bluuebunny/crossref_metadata_2025 huggingface dataset:
Galactic Cosmic-Ray Anisotropy in the Northern Hemisphere from the ARGO-YBJ Experiment during 2008–2012
Authors: Bartoli B. , Bernardini P. , Bi X. J. , Cao Z. , Catalanotti S. , Chen S. Z. , Chen T. L. , Cui S. W. , Dai B. Z. , D’Amone A. , Danzengluobu  , De Mitri I. , Piazzoli B. D’Ettorre , Di Girolamo T. , Di Sciascio G. , Feng C. F. , Feng Z. Y. , Gao W. , Gou Q. B. , Guo Y. Q. , He H. H. , Hu Haibing , Hu Hongbo , Iacovacci M. , Iuppa R. , Jia H. Y. , Labaciren  , Li H. J. , Liu C. , Liu J. , Liu M. Y. , Lu H. , Ma L. L. , Ma X. H. , Mancarella G. , Mari S. M. , Marsella G. , Mastroianni S. , Montini P. , Ning C. C. , Perrone L. , Pistilli P. , Ruffolo D. , Salvini P. , Santonico R. , Shen P. R. , Sheng X. D. , Shi F. , Surdo A. , Tan Y. H. , Vallania P. , Vernetto S. , Vigorito C. , Wang H. , Wu C. Y. , Wu H. R. , Xue L. , Yang Q. Y. , Yang X. C. , Yao Z. G. , Yuan A. F. , Zha M. , Zhang H. M. , Zhang L. , Zhang X. Y. , Zhang Y. , Zhao J. , Zhaxiciren  , Zhaxisangzhu  , Zhou X. X. , Zhu F. R. , Zhu Q. Q. ,   (The ARGO-YBJ Collaboration)
Published: July 2018

This paper reports on the observation of the sidereal large-scale anisotropy of cosmic rays using data collected by the ARGO-YBJ experiment over 5 years (2008–2012). This analysis extends previous work limited to the period from 2008 January to 2009 December, near the minimum of solar activity between cycles 23 and 24. With the new data sample, the period of solar cycle 24 from near minimum to maximum is investigated. A new method is used to improve the energy reconstruction, allowing us to cover a much wider energy range, from 4 to 520 TeV. Below 100 TeV, the anisotropy is dominated by two wide regions, the so-called “tail-in” and “loss-cone” features. At higher energies, a dramatic change of the morphology is confirmed. The yearly time dependence of the anisotropy is investigated. Finally, no noticeable variation of cosmic-ray anisotropy with solar activity is observed for a median energy of 7 TeV.
Cyclic Changes of the Sun’s Seismic Radius
Authors: Kosovichev Alexander , Rozelot Jean-Pierre
Published: July 2018

The questions asking whether the Sun shrinks with the solar activity and what causes this have been a subject of debate. Helioseismology provides a means to measure with high precision the radial displacement of subsurface layers, the so-called “seismic radius,” through the analysis of oscillation frequencies of surface gravity (f) modes. Here, we present results of a new analysis of 21 years of helioseismology data from two space missions, the Solar and Heliospheric Observatory and the Solar Dynamics Observatory, which allow us to resolve previous uncertainties and compare variations of the seismic radius in two solar cycles. After removing the f-mode frequency changes associated with the surface activity, we find that the mean seismic radius is reduced by 1–2 km during the solar maxima and that most significant variations of the solar radius occur beneath the visible surface of the Sun at a depth of about 5 ± 2 Mm, where the radius is reduced by 5–8 km. These variations can be interpreted as changes in the solar subsurface structure caused by the predominately vertical ∼10 kG magnetic field.
X-Ray and Optical Studies of the Redback System PSR J2129–0429
Authors: Al Noori Hind , Roberts Mallory S. E. , Torres Rodrigo A. , McLaughlin Maura A. , Gentile Peter A. , Hessels Jason W. T. , Ray Paul S. , Kerr Matthew , Breton Rene P.
Published: July 2018

PSR J2129−0429 is a 7.62 ms eclipsing millisecond pulsar (MSP) with a non-degenerate binary companion star that is likely in an early stage of the recycling process. It has one of the largest companion masses of a so-called “redback” (0.4 M
⊙) and has an unusually high surface magnetic field (1.6 × 109 G) for an MSP. We present here an X-ray and optical study of PSR J2129−0429 using new NuSTAR and LCOGT data of the system in addition to archival Swift and XMM-Newton data. Its X-ray light curve shows strong orbital variation from the intra-binary shock, about five times greater than is typical for other systems, and is clearly and persistently double-peaked. Its X-ray spectrum has a very hard power-law component (Γ = 1.1–1.2) which extends to ∼40 keV and exhibits an efficiency of up to a few percent in the X-ray band. The X-ray spectrum at the second peak of the light curve exhibits strong variability, while the spectrum of the first peak remains constant across observations. The hardness of the spectrum is suggestive of driven magnetic reconnection occurring at the shock. In addition, we observe the companion to be currently optically brightening after a multi-year period where it was dimming. The changes in color suggest that it has been continually cooling, implying that the companion is currently expanding.
A new species of the genus Blaptogonia from the Himalayas with four DNA markers (Coleoptera, Tenebrionidae, Blaptini)
Authors: Li Xiu-min , Bai Xing-long , Ren Guo-dong
Published: July 2018

A new species of the genusBlaptogoniaMedvedev, 1998,B.zhentangasp. n., is described from the southern Himalayas of China. Two fragments of mitochondrial protein-coding genes (COI, Cytb), one fragment of mitochondrial ribosomal RNA gene (16S), and one fragment of nuclear rRNA gene (28SD2) of the new species were obtained. A key to the known species of the genus is presented.
Emotional responses to innovative Science teaching methods: Acquiring emotional data in a General Science teacher education class
Authors: Sanchez-Martin Jesus , Cañada-Cañada Florentina , Dávila-Acedo María Antonia
Published: July 2018

The current work tries to inquiry how different teaching methods affect on the student’s emotional performance. The traditional questionnaire for data collection has been replaced by in-situ, on-line-assisted, survey. This instrument was continoulsy applied over the course of 17 General Science lessons.  The experiment involved 120 prospective primary education teachers. Emotions to choose: rejection, boredom, satisfaction, surprise and the teaching methods involved were pure oral presentation, oral presentation with gamification, oral presentation with audiovisual support, oriented research, and hands-on activities.  When the teaching method was changed to gamification or hands-on activities, the prospective teachers felt dynamic emotions, whereas they generally felt satisfaction or boredom (static emotions) with a traditional pure oral presentation.  The students mainly identified the teaching method as being the most influential reason for having chosen their prevalent emotion, reflected in a dramatic increase in emotional performance when they were taught with innovative methods.
La escalera del Real Colegio Seminario de Corpus Christi de Valencia (1599-1601): hipótesis de traza
Authors: Marín R. , López M.ª C.
Published: July 2018

Las escaleras claustrales con tramos volados representan la aportación más relevante del brillante episodio de la estereotomía valenciana de la Edad Moderna.
Este artículo muestra los resultados del análisis gráfico realizado a la escalera del Real Colegio de Corpus Christi de Valencia, su ejemplar más representativo, para determinar su posible traza. Con el apoyo de un levantamiento telemétrico mediante escáner láser 3D se ha constatado la existencia de un logrado método gráfico de diseño. El estudio ha considerado las operaciones que recomiendan los manuscritos de cantería y la tradición constructiva de sus predecesoras, las escaleras «de honor» de las casas nobles mediterráneas.
Esto ha permitido calibrar una estrategia de análisis útil para el estudio de otros ejemplos análogos; ponderar las informaciones ofrecidas por los tratadistas y confirmar la vigencia de los procedimientos tardomedievales de control de la forma mediante curvas directrices.
Caminos frustrados hacia la prefabricación arquitectónica. Estudio del sistema murario en las construcciones asociadas a la línea ferroviaria Teruel-Alcañiz
Authors: Verdejo P. , López G. , Mocholí G.
Published: July 2018

La historia de la construcción no siempre ha estado repleta de éxitos en el desarrollo de nuevos sistemas constructivos, sin embargo, todos ellos han servido para desarrollar los avances que hoy en día conocemos. A finales del siglo XIX y principios de XX, la incipiente industria comenzará a dotar de nuevos materiales hacia la optimización constructiva. La arquitectura industrial hará uso de todos estos nuevos productos, formulándose como crisol de experimentación y desarrollo. El estudio de estos elementos prefabricados que materializaron las edificaciones hoy abandonadas de la línea ferroviaria Teruel-Alcañiz, permite, además de comprobar su estrategia para hacer frente a la ejecución de un elevado número de edificaciones en tempo y presupuesto limitados, afrontar bajo su conocimiento futuros trabajos de intervención.
Dimensionado de las escaleras protegidas en caso de incendio: un reto para los métodos prescriptivos (El modelo del CTE)
Authors: Echeverría J. B. , Fernández-Vigil M. , Gil B.
Published: July 2018

El dimensionado de las escaleras en caso de incendio se encuentra entre las características más importantes del diseño arquitectónico actual. La mayor complejidad de los edificios (usos mixtos, espacios con alta ocupación, personas con discapacidad, edificios en altura, etc.) se suma a nuevos hábitos sociales, y las actividades que se desarrollaban tradicionalmente en las partes bajas de los edificios, tienden a ocupar los pisos más altos. Este artículo muestra que los cálculos prescriptivos para el dimensionado de las escaleras protegidas son incapaces de enfrentarse a este reto por estar basados en modelos simplificados, solamente válidos para edificios y distribuciones convencionales. Analiza el caso del Código Técnico de la Edificación español, mostrando su debilidad, e introduce los conceptos de diseño prestacional necesarios para entender el problema. Concluye que cualquier diseño complejo debe abordarse estudiando el movimiento real de los ocupantes, que puede ser modelizado con la ayuda de herramientas computacionales.
Aplicación del ajuste de Rietveld para correlacionar la evolución microestructural de fundiciones blancas con 18 y 25% en Cromo, templadas en aceite y sucesivos revenidos, con el comportamiento frente al desgaste abrasivo y esfuerzos de flexión
Authors: Álvarez Antolín José F. , Francos Garrote Laura , Asensio Lozano Juan
Published: July 2018

Mediante la aplicación del método de afinamiento estructural de Rietveld se identificaron y cuantificaron las fases presentes en fundiciones blancas hipoeutécticas con 18 y 25% en Cromo, templadas en aceite y tras sucesivos revenidos a 500 ºC. Se correlacionaron los resultados con su comportamiento frente al desgaste abrasivo y bajo esfuerzos de flexión. En ambos casos el porcentaje de austenita retenida tras el temple resultó mínima. Durante los sucesivos revenidos, se constató en la calidad con 18% en Cromo una redisolución parcial de los carburos M7C3 junto a una transformación entre carburos mixtos secundarios M7C3 y M2C. La Martensita tras temple resultó un factor clave frente a la resistencia al desgaste abrasivo, resultando los revenidos tras el temple en aceite desfavorables para esta propiedad. La calidad con 25% en Cromo fue la que presentó un mayor contenido en martensita tras el temple, y por tanto la que mejor comportamiento presentó frente a este tipo de desgaste. Esta misma calidad, tras el doble revenido, fue la que mayor resistencia y capacidad de deformación alcanzó bajo esfuerzos a flexión. La fractura resultó frágil y mayoritariamente transgranular. Sin embargo, pudo observarse la presencia de zonas con fractura dúctil asociadas a martensita doblemente revenida.
A visão clássica da ameaça do desemprego tecnológico
Authors: Couto Joaquim Miguel , Freitas Carlos Eduardo de , Couto Ana Cristina Lima
Published: July 2018

A questão do desemprego tecnológico preocupou a mente de dois dos maiores pensadores da ciência econômica: David Ricardo e Karl Marx. Ambos acreditaram que a introdução de novas máquinas poderia causar uma situação de desemprego crônico durante certo período de tempo, prejudicial a classe trabalhadora. O movimento luddita do início do século XIX deixou claro que o desemprego tecnológico era um fenômeno real. No entanto, os autores reconheceram que o desemprego tecnológico poderia ser evitado caso novos investimentos absorvessem a mão-de-obra dispensada pela introdução de nova maquinaria. Ou seja, tudo dependeria da velocidade do desenvolvimento da tecnologia e do crescimento da economia, aliada ainda ao crescimento da população e da redução da jornada de trabalho.
Avaliação de Indicadores Socioeconômicos dos Grupos 1 e 5 de Municípios Paulistas com o Uso da Análise de Regressão Logística
Authors: Gouvêa Maria Aparecida , Farina Milton Carlos , Varela Patrícia Siqueira
Published: July 2018

Este trabalho faz parte de um amplo estudo que combina diversos grupos de municípios paulistas analisados mediante técnicas estatísticas multivariadas.Este trabalho objetivou indicar se os municípios paulistas, caracterizados pelo Índice de Responsabilidade Social Paulista (IPRS) como “municípios-polo” (grupo 1) e municípios de baixo desenvolvimento econômico e social (grupo 5), podem ser diferenciados pelos valores per capita de transferência do Fundo de Participação dos Municípios (FPM), quota-parte do Imposto sobre Circulação de Mercadorias e Serviços (ICMS) e receita tributária arrecadada, com base na regressão logística. Esta técnica estatística sinalizou que a variável Receita Tributária é a que mais discrimina os dois grupos de municípios. É possível dizer que, no caso destes dois grupos, os critérios de distribuição do FPM também são aplicados de forma diferenciada, contribuindo de forma efetiva para a eqüidade das receitas disponíveis, apoiando os governos municipais no desenvolvimento de suas políticas públicas.
Razões do endividamento público federal (1995-2006)
Authors: Couto Joaquim Miguel , Couto Ana Cristina Lima , Custódio Marlon Saturnino
Published: July 2018

Um dos pontos mal explicados e desconhecidos da macroeconomia brasileira é o crescimento da Dívida Pública Mobiliária Federal interna (DPMFi). Entre o final de 1994 e o final de 2006, a DPMFi elevou-se de forma extraordinária: de R$ 61,782 bilhões para R$ 1.094,724 bilhões. As razões mais comentadas do seu crescimento (déficit fiscal, esqueletos, esterilização monetária, entre outros) não são a principal causa. Existe um responsável oculto que tem passado despercebido pelos analistas do setor público. Trata-se do chamado “ajuste de liquidez”, operações realizadas pelo Banco Central para enxugar o excesso de liquidez dos bancos brasileiros. Ao utilizar títulos públicos para enxugar a liquidez do sistema financeiro, o Banco Central tornou-se o principal responsável pelo crescimento da DPMFi no período.
A PRODUÇÃO DO CONHECIMENTO CIENTÍFICO E DA CIÊNCIA ECONÔMICA: UMA PERSPECTIVA HISTÓRICA
Authors: Izepão Rosalina Lima , Almeida Virgílio de
Published: July 2018

Resumo: O artigo apresenta a história da produção do conhecimento científico e da Economia, com o objetivo de evidenciar, neste contexto, a evolução das discussões metodológicas e de algumas controvérsias que têm envolvido a investigação econômica ao longo do tempo. Trata-se de uma pesquisa exploratória, na qual se utilizou fontes bibliográficas, por meio das quais se analisou diferentes abordagens sobre o tema de estudo, concluindo-se que: assim como ocorre nas demais ciências, na Ciência Econômica, os métodos e as leis estão em constantes transformações, pois, os critérios de cientificidade são historicamente abrangentes e controversos. De forma que, ao mesmo tempo, geram e são gerados pelas transformações históricas e culturais de cada época.  conhecimento científico, Ciência Econômica, metodologia.
O PIB VERDE INDUSTRIAL DO ESTADO DO PARANÁ
Authors: Godoi Gonzalez Marcos Henrique , De Albuquerque Marcela Ribeiro
Published: July 2018

Este trabalho busca oferecer uma medida do grau de sustentabilidade da atividade industrial no estado do Paraná no período de 1996 a 2005, por meio da metodologia do PIB verde. Esta metodologia deduz do PIB normalmente estimado a depleção mineral e o custo de controle da degradação ambiental, sendo o primeiro igual ao valor da produção mineral comercializada e o segundo calculado através da aplicação das proxys da metodologia do International Pollution Projection System (IPPS) do Banco Mundial, a cada um dos setores da indústria. Fora aplicada apenas ao setor secundário da economia, devido a limitações da própria metodologia. A comparação entre o PIB convencional e o PIB verde nos permite ter uma noção da sustentabilidade da economia, pois quanto maior a distância entre o PIB verde e o PIB convencional, menos sustentável é a economia. No estado do Paraná, averiguou-se que a sustentabilidade da indústria é alta, entretanto, tal resultado pode ter refletido, em parte, limitações da metodologia, que não consideram a depleção mineral feita fora do território paranaense, mas que é indispensável para parte considerável de suas indústrias, principalmente das indústrias da transformação.
DETERMINANTES MACROECONÔMICOS DA TAXA DE SACRIFÍCIO DO CONTROLE INFLACIONÁRIO NO BRASIL: EVIDÊNCIAS EMPÍRICAS UTILIZANDO O MODELO VEC.
Authors: Ramalho Ribeiro da Fonseca Mateus , De Araujo Eliane Cristina
Published: July 2018

O presente artigo tem por objetivo analisar a taxa de sacrifício do controle da inflação no Brasil, pós-implantação do regime de metas de inflação (RMI). Primeiramente, a pesquisa aborda uma investigação teórica sobre os tipos existentes de inflação, as relações entre taxa de juros, inflação e crescimento econômico, os tipos de expectativas que regem as condutas dos agentes, e a forma de cálculo da taxa de sacrifício. Em seguida, expõe o comportamento histórico das principais variáveis macroeconômicas no Brasil, que compreende o período de 2000 a 2012. Após a discussão teórica, faz-se uma pesquisa empírica, utilizando um modelo econométrico de vetores autoregressivos (VAR), que evidencia a taxa de sacrifício do controle da inflação imposta no Brasil, através da política monetária. Como resultado, este trabalho conclui que a política monetária tem gerado um alto custo para a sociedade brasileira, e consequentemente, uma elevada taxa de sacrifício do controle da inflação, como também, reflete em vários âmbitos da economia brasileira. A politica monetária tem como principal instrumento de condução as taxas de juros, que quando elevadas, produzem alguns efeitos: (i) a redução lenta da inflação; (ii) redução quase que imediata do crescimento do PIB; (iii) o aumento da dívida pública federal; e (iv) e uma crescente apreciação cambial. Devido à defasagem temporal da política monetária, eleva-se algum tempo para surtir efeito, quando tal política é feita, principalmente sobre a inflação. Contudo, sobre o produto e câmbio, o efeito é sentido quase que imediato, gerando aspectos negativos em nossa economia.
Qualidade e Equidade na Educação: A Hipótese da Curva de Kuznets Educacional
Authors: Neves Leonardo , Almeida Eduardo
Published: July 2018

Este artigo objetivou compreender o relacionamento entre eficácia e qualidade educacionais, considerando, por base teórica a função-produção educacional. O trabalho consistiu na estimação de um painel de efeitos fixos, tendo o desvio-padrão das notas médias na Prova Brasil de 2007 e 2009 por variável dependente, controlada para um conjunto de variáveis explicativas socioeconômicas e educacionais, em médias municipais. A hipótese central testada foi a existência de uma relação em formato de U invertido entre a equidade e eficácia educacionais, seguindo a proposição da Curva de Kuznets, adaptada para mensurar a qualidade educacional. Os resultados indicaram que, embora não tenha se confirmado a hipótese da Curva de Kuznets, não foi verificada a existência de um trade-off  entre desigualdade e qualidade educacionais.
Comparison of calcaneus joint internal and external fractures in open surgery and minimal invasive methods in patients
Authors: Amani Alireza , Shakeri Vahid , Kamali Alireza
Published: July 2018

Surgical management of calcaneal fractures has various complications. In recent years, minimally invasive surgeries have been utilized for a wide range of surgical procedures on different body parts significantly declining complications. This paper compares surgical outcomes of calcaneal fracture management between the open reduction and internal fixation technique (ORIF) and the MIS technique. In this randomized clinical trial forty patients with calcaneus fractures were randomly assigned to two equal groups; ORIF group and MIS group. Patients were followed for 1 year post-operatively. Gissane and Bohler’s angles, AOFAS questionnaire, pain intensity, ability to conduct previous activities and various complications like wound healing complications and irritation with shoe wear were assessed in the final post-operative visit. Eventually data obtained from the two groups were compared. All patients obtained fracture union. Bohler’s and Gissane angles significantly increased and decreased, respectively, after the operation in both groups (p<0.05), however, no significant difference was found between the two research groups. AOFAS scores and pain intensity was similar in both groups, however, surgical duration in the MIS group was significantly less than the ORIF group (P=0.021). Only one patient from the ORIF group was not able to resume his previous occupation. 12 patients from the ORIF group and five patients from the MIS group experienced irritation from shoe wear (p=0.025). In the ORIF group, 4 patients suffered from wound healing complications, however, none of the patients of the MIS group had wound complications (p=0.035). In conclusion, based on the results, it can be concluded that the MIS technique demonstrated better functional and radiographic outcomes as well as a more favorable complication profile, thus, it is recommended for the management of calcaneus fractures.
Analysis of correlation between estradiol and fracture of femur neck
Authors: Sharifi Mohammad Davood , Mohebbi Masoud , Farrokhfar Mahmood , Farzaneh Roohie , Disfani Hamideh Feiz , Hashemian Amir Masoud
Published: July 2018

Osteoporosis is a major public health challenge all over the world. Estrogen hormone was cited amongst other hormones to be an efficient hormone for the production and maintenance of bone density. This study was designed with the purpose of evaluating and analyzing the estradiol effect on fractures of femur neck in the Iranian society. This study evaluated men over 50 years of age suffering with mild trauma (falling off the same level height or lower) and with a fracture on their femur neck. Also, their serum level of estradiol was measured with an ELISA method. Using this procedure, the patients were assigned into groups with either normal estradiol serum level (10pg/ml and higher) or with lower than normal level (lower than 10 pg/ml). A control group including 50-year-old and older men without hip fracture, or its history, was chosen to access their estradiol serum level. Data collected from these two groups were statistically compared. A total of 120 patients were evaluated (60 in the control and 60 in the test group). The mean age of patients in the control and test groups were 67.9±10.22 and 69.5±8.84 years, respectively (p=0.376). Smoker patients’ percentages in the control and test groups were 35% and 31.7%, respectively (p=0.699). On the basis of the serum estradiol level, patients’ percentages with low estradiol level in control and test groups were 10% and 16.7%, respectively (p=0.283). The only significant factor in predicting serum estradiol level was smoking. In conclusion, in this study it was observed that fractures of the femoral neck following a mild trauma were not correlated to low level of serum estradiol.
Anti-bacterial properties of calcium hydroxide in combination with silver, copper, zinc oxide or magnesium oxide
Authors: Yousefshahi Hazhir , Aminsobhani Mohsen , Shokri Mehdi , Shahbazi Razieh
Published: July 2018

Prevention of bacterial growth among root canal treatment sessions is a prerequisite for successful root canal treatment. The most common way to achieve this is to use calcium hydroxide in the treatment sessions. Some studies have shown calcium hydroxide inefficiency in this field. The aim of this study was to investigate and compare the effects of silver, copper, zinc oxide and magnesium oxide nanoparticles on the inhibitory effects of calcium hydroxide based on Enterococcus faecalis species. Enterococcus faecalis bacteria having 0.5 McFarland concentration were prepared. Plates containing BHI agar medium were prepared. In each plate, four wells were created and the plate was cultured using a sterile swab. Afterwards, calcium hydroxide composition of 1% and 2% concentration from silver, copper, zinc oxide and magnesium oxide nanoparticles were prepared separately, as well as the combination of calcium hydroxide with 1% silver in combination with 1% of copper, zinc oxide and magnesium oxide nanoparticles, which were then transferred to the wells. After 24 hours of incubation, the inhibition zone diameter was measured. Data were analyzed by Mann-Withney test. At 1% concentration, only the combination of copper nanoparticles with calcium hydroxide could significantly create an inhibition zone larger than calcium hydroxide alone (P<value 0.5). At 2% concentration, the combination of copper nanoparticles with calcium hydroxide, and the combination of silver nanoparticles with calcium hydroxide, were significantly higher than calcium hydroxide alone (P<value 0.5). The calcium hydroxide composition containing 1% silver nanoparticles in combination with 1% copper, zinc oxide and magnesium oxide nanoparticles significantly increased the growth inhibition zone more than calcium hydroxide alone. (P<Value 0.5). Copper nanoparticles showed the best antibacterial properties among silver, copper, magnesium oxide and zinc oxide nanoparticles in combination with calcium hydroxide. Also, the combination of 1% of nanoparticles with each other increases antibacterial properties.
Chemotherapy-induced muscle wasting: an update
Authors: Coletti Dario
Published: July 2018

The majority of cancers are associated to cachexia, a severe form of weight loss mostly accounted for by skeletal muscle wasting. Cancer patients are often treated with chemotherapy, whose side effects are at times neglected or underestimated. Paradoxically, chemotherapy itself can induce muscle wasting with severe, cancer-independent effects on muscle homeostasis. Since muscle wasting is a primary marker of poor prognosis for cancer patients and negatively affects their quality of life, the systemic consequences of chemotherapy in this context must be fully characterized and taken into account. Ten years ago a precursor study in an animal cancer model was published in the European Journal of Translation Myology (back then, Basic and Applied Myology), highlighting that the side effects of chemotherapy include muscle wasting, possibly mediated by NF-κB activation. This paper, entitled «Chemotherapy-induced muscle wasting: association with NF-κB and cancer cachexia», is now being reprinted for the inaugural issue of the «Ejtm Seminal Paper Series». In this short review we discuss those results in the light of the most recent advances in the study of chemotherapy-induced muscle wasting.
Myeloid sarcoma without circulating leukemia mimicking gastrointestinal malignancy and lymphoma
Authors: Ravulapati Sravanthi , Siegel Craig , Dara Ameesh , Lionberger Jack M.
Published: July 2018

We present an unusual case of myeloid sarcoma with ascites and abdominal pain in which initial clinical, laboratory, and imaging studies suggested a gastrointestinal malignancy or lymphoma. Subsequent detection of leukemic ascites and blasts in a gastric, small bowel, and skin biopsy supported a diagnosis of myeloid sarcoma. Bone marrow biopsy revealed 15% blasts, and cytogenetics with an inversion 16 rearrangement was diagnostic of acute myeloid leukemia (AML). Positron emission tomography-computed tomography performed at presentation to stage a presumptive lymphoma found later utility in following the burden of extramedullary disease. Standard AML induction chemotherapy resulted in complete remission and was followed by three rounds of high dose cytarabine consolidation. The patient unfortunately relapsed leading to re-induction followed by allogeneic stem cell transplantation. This report describes the presentation, assessment, and management of myeloid sarcoma.
Evaluation of post-fermentation heating times and temperatures for controlling Shiga toxin-producing Escherichia coli cells in a non-dried, pepperoni-type sausage
Authors: Shane Laura E. , Porto-Fett Anna C.S. , Shoyer Bradley A. , Phebus Randall K. , Thippareddi Harshavardhan , Hallowell Ashley , Miller Kelsey , Foster-Bey Lianna , Campano Stephen G. , Taormina Peter J. , Glowski Daniel L. , Tompkin Robert B. , Luchansky John B.
Published: July 2018

Coarse ground meat was mixed with non-meat ingredients and starter culture (Pediococcus acidilactici) and then inoculated with an 8-strain cocktail of Shiga toxinproducing Escherichia coli (ca. 7.0 log CFU/g). Batter was fine ground, stuffed into fibrous casings, and fermented at 35.6°C and ca. 85% RH to a final target pH of ca. pH 4.6 or ca. pH 5.0. After fermentation, the pepperoni- like sausage were heated to target internal temperatures of 37.8°, 43.3°, 48.9°, and 54.4°C and held for 0.5 to 12.5 h. Regardless of the heating temperature, the endpoint pH in products fermented to a target pH of pH 4.6 and pH 5.0 was pH 4.56±0.13 (range of pH 4.20 to pH 4.86) and pH 4.96±0.12 (range of pH 4.70 to pH 5.21), respectively. Fermentation alone delivered ca. a 0.3- to 1.2-log CFU/g reduction in pathogen numbers. Fermentation to ca. pH 4.6 or ca. pH 5.0 followed by post-fermentation heating to 37.8° to 54.4°C and holding for 0.5 to 12.5 h generated total reductions of ca. 2.0 to 6.7 log CFU/g.
Change of macrobenthic communities in the 1930s, 1970s and 2015 in the mesotrophic Lake Nojiri, Central Japan
Authors: Hirabayashi Kimio , Ichikawa Makoto , Okada Shunsuke , Yamamoto Masaru
Published: July 2018

We documented the current status of the macrobenthic community of Lake Nojiri (surface area: 4.56 km2; maximum depth: 38.5 m; altitude: 654 m above sea level; mesotrophic lake), and examined changes over time in the densities of chironomids and oligochaetes, by comparison with previous quantitative data of the lake reported in 1931 and 1973. We discussed the succession of benthic macroinvertebrates in relation to changes in the lake bottom environment, as evidence of lake eutrophication. On March 10, 2015, a bathymetrical sampling survey was carried out using a standard Ekman grab at each of the 5 stations (min. ca. 6 m – max. ca. 27 m) in Lake Nojiri. The average densities of the benthic communities for all the stations were ca. 5000m-2, comprised principally of oligochaetes ca. 2800 m-2 (57%) and chironomids ca. 2100 m-2 (43%), whereas their benthic biomass averaged ca. 9.7 g m-2, chironomids ca. 7.6 g m-2 (77%) and oligochaetes ca. 2.3 g m-2 (23%). In the shallower stations, the dominant species was Heterotrissocladius sp., but Chironomus nipponensis Tokunaga was the dominant species in the deeper stations. The densities of C. nipponensis was ca. 14 times higher than those reported by Miyadi in 1931 and 4 times higher than reported by Kitagawa in 1973a. In recent years the density of the oligochaete Tubifex tubifex, has tended to increase and the anoxic- and anaerobic-layer have thickened, especially in deeper regions where they are widely distributed. Moreover, we found differences in the C. nipponensis larval growth rate with water depth, i.e., small IV-instar larvae that dominated at the deepest Station 5. At this station, we suggest that low dissolved oxygen concentration and low water temperature during summer-fall suppresses growth of C. nipponensis. Large environmental changes must have affected chironomid and oligochaete densities and growth rate of C. nipponensis, especially in the deeper regions with low dissolved oxygen concentrations, low water temperature and high organic matter (ignition loss; 15.0% in St. 4 and 13.9% in St. 5) in the sediments. This is a strong evidence that the eutrophication of this lake is continuing.
Infant psychomotor development in cases of maternal postpartum depression: Observation of a mother and baby unit
Authors: Le Treut Laure , Poinso François , Grandgeorge Pauline , Jouve Elisabeth , Dugnat Michel , Sparrow Joshua , Guivarch Jokthan
Published: July 2018

Studies of the first year of infant psychomotor development in cases of maternal postpartum depression are lacking. The mother and baby unit (MBU) is a healthcare system available to infants and their mothers during the postpartum period in a psychiatric hospital, which provides support and preserves the parent’s role in the child’s daily care. The aim of the paper is to describe the developmental profile of babies of mothers with severe postpartum depression treated in an MBU through the developmental quotients. Using the Brunet- Lézine scale, we studied six-month-old infants whose mothers were hospitalized. The study population consisted of 15 infants. The mean global developmental quotient score was 96.7. A developmental quotient lower than 80 was not observed for any of the children. We found no global psychomotor developmental delays. Despite this, the posture subscore was the area in which we observed the most difficulties. It is possible that the tonic dialogue between the mother and infant is disrupted by maternal depression.
Anti-stress effects of simplified aroma hand massage
Authors: Komori Teruhisa , Kageyama Mutsumi , Tamura Yuko , Tateishi Yuki , Iwasa Takashi
Published: July 2018

In order to be able to use the aroma hand massage as a skill that can be done by a nurse who does not have a special aromatherapy technique, we examine antistress effects of simplified aroma hand massage for healthy subjects. We evaluated the anti-stress action of aroma hand massage and the different components of the procedure in 20 healthy women in their twenties. We used autonomic nervous function measured via electrocardiogram as an index of stress. After conducting a baseline electrocardiogram, we induced stress in the participants by asking them to spend 30 minutes completing Kraepelin’s arithmetic test. We then administered various treatments and examined the anti-stress effects. Kraepelin’s test significantly increased sympathetic nervous function and significantly reduced parasympathetic nervous function. Compared with massage without essential oil or aroma inhalation, aroma hand massage significantly increased parasympathetic nervous function and significantly decreased sympathetic nervous function. The effect of the aroma hand massage persisted when the procedure was simplified. The anti-stress action of the aroma hand massage indicates that it might have beneficial application as a nursing technique. There are several limitations in this study; ambiguities of low component/high component ratio of heart rate variability and bias by small subjects groups of the same women.
The relaxation effect of prolonged expiratory breathing
Authors: Komori Teruhisa
Published: July 2018

This study was performed to confirm that autonomic nervous activity is affected by breathing speed. I hypothesized that prolonged expiratory breathing would promote parasympathetic dominance, whereas rapid breathing would promote sympathetic dominance. Ten healthy men, ages 21–28 years old, were instructed to perform prolonged expiratory breathing (6 seconds expiration, 4 seconds inspiration) after spontaneous breathing and rapid breathing (1 second expiration, 1 second inspiration) after spontaneous breathing; changes in high frequency (HF) and low frequency (LF)/HF of heart rate variability (HRV) were measured during each type of breathing. During prolonged expiratory breathing, parasympathetic nervous function was significantly activated. Conversely, during rapid breathing, parasympathetic nervous function was significantly suppressed. The HRV method assessing sympathetic and parasympathetic modulation in this study is an indirect, non-invasive method with clear limitations. The use of additional techniques should be considered to clarify the relationships between the breathing speed and the mind.
Bubbles and droplets in a singular limit of the FitzHugh–Nagumo system
Authors: Chen Chao-Nien , Choi Yung-Sze , Ren Xiaofeng
Published: July 2018

The FitzHugh–Nagumo system gives rise to a geometric variational problem, when its parameters take values in a particular range. A stationary set of the variational problem satisfies an Euler–Lagrange equation that involves the curvature of the boundary of the set and a nonlocal term that inhibits unlimited growth and spreading. The nonlocal term is the solution of a nonhomogeneous modified Helmholtz equation with the characteristic function of the stationary set as the inhomogeneous term. Two types of stationary sets are studied: disc shaped stationary sets in the plane, termed bubbles, and unions of perturbed small discs, termed droplet assemblies, in bounded domains. A complete description of the existence and the stability of bubbles is established. Depending on the parameters, there may be zero, one, two, or even three bubbles. Droplet assemblies are constructed by a reduction argument. Each droplet in a stationary assembly is close in size and shape to the corresponding bubble in the plane. The locations of the droplets in the assembly are determined by the Green’s function of the modified Helmholtz equation.
The calculus of thermodynamical formalism
Authors: Giulietti Paolo , Kloeckner Benoît R. , Lopes Artur O. , Marcon Diego
Published: July 2018

Given an onto map

T

acting on a metric space

\Omega

and an appropriate Banach space of functions

\mathcal X(\Omega)

, one classically constructs for each potential

A \in \mathcal X

a transfer operator

\mathscr L_A

acting on

\mathcal X(\Omega)

. Under suitable hypotheses, it is well-known that

\mathscr L_A

has a maximal eigenvalue

\lambda_A

, has a spectral gap and defines a unique Gibbs measure

\mu_A

. Moreover there is a unique normalized potential of the form

B=A+f-f\circ T+c

acting as a representative of the class of all potentials defining the same Gibbs measure.

The goal of the present article is to study the geometry of the set of normalized potentials

\mathcal N

, of the normalization map

A\mapsto B

, and of the Gibbs map

A\mapsto \mu_A

. We give an easy proof of the fact that

\mathcal N

is an analytic submanifold of

\mathcal X

and that the normalization map is analytic; we compute the derivative of the Gibbs map; last we endow

\mathcal N

with a natural weak Riemannian metric (derived from the asymptotic variance) with respect to which we compute the gradient flow induced by the pressure with respect to a given potential, e.g. the metric entropy functional. We also apply these ideas to recover in a wide setting existence and uniqueness of equilibrium states, possibly under constraints.
Volume conjectures for the Reshetikhin–Turaev and the Turaev–Viro invariants
Authors: Chen Qingtao , Yang Tian
Published: July 2018

We consider the asymptotics of the Turaev–Viro and the Reshetikhin–Turaev invariants of a hyperbolic 3-manifold, evaluated at the root of unity exp

({2\pi\sqrt{-1}}/{r})

instead of the standard exp

({\pi\sqrt{-1}}/{r})

. We present evidence that, as

r

tends to

\infty

, these invariants grow exponentially with growth rates respectively given by the hyperbolic and the complex volume of the manifold. This reveals an asymptotic behavior that is different from that of Witten's Asymptotic Expansion Conjecture, which predicts polynomial growth of these invariants when evaluated at the standard root of unity. This new phenomenon suggests that the Reshetikhin–Turaev invariants may have a geometric interpretation other than the original one via

SU(2)

Chern–Simons gauge theory.
The classification of $3^n$ subfactors and related fusion categories
Authors: Izumi Masaki
Published: July 2018

We investigate a (potentially infinite) series of subfactors, called

3^n

subfactors
, including

A_4

,

A_7

, and the Haagerup subfactor as the first three members corresponding to

n=1,2,3

. Generalizing our previous work for odd

n

, we further develop a Cuntz algebra method to construct

3^n

subfactors and show that the classification of the

3^n

subfactors and related fusion categories is reduced to explicit polynomial equations under a mild assumption, which automatically holds for odd

n

. In particular, our method with

n=4

gives a uniform construction of

4

finite depth subfactors, up to dual, without intermediate subfactors of index

3+\sqrt{5}

. It also provides a key step for a new construction of the Asaeda–Haagerup subfactor due to Grossman, Snyder, and the author.
Aula Faesa e storytelling: um estudo de caso sobre os impactos no rendimento escolar
Authors: de Moura Ralf Luiz
Published: July 2018

ThehighereducationstudentskillsinBrazilhaschangedandtheschoolsandtheteachingpracticeitselfarealsochanging.Schoolsthatofferhighereducationcoursesareincreasinglyconcernedwiththepotentialoflearningthathasbeencreatingtheir own methodologies or different ways of dealing with this new student. The use of active methodologies, diagnosticevaluations and dynamic planning, are some of the encouraged guidelines for improving learning and consequentlyschoolperformance.ThepurposeofthisstudywastoanalyzetheAulaFaesaguidelinesandproposeatheoreticalmodeltovalidate the impact of some Faesa guidelines on a causal relation to student achievement, including the use of an activemethodology known as Storytelling. A quantitative research using questionnaires submitted to students from two classesof the Faesa Information Systems course was carried out in 2017. The results showed that all aspects of the Faesa Classcontribute positively to the student’s performance, except for the use of the forum that may was not well adapted to thediscipline.Attendancewasthemostimportantelementinthecontributionofstudentachievement
Estudando na prática: como motivar os alunos a estudarem a teoria por meio da verificação das práticas de mercado
Authors: Lobo Veríssimo da Silva Gustavo
Published: July 2018

Thepurposeofthisarticleistopresentateachingmethodthatwasappliedinundergraduateclassesandtodisseminatethepractice of innovative methodologies in the classroom, making the educational process more effective. It will be demonstratedto the reader the whole process involving the adopted method, going through the planning, execution and obtained results. Thereader will note that the employed practices took into account the directives of the higher education institution, FAESA, andhavingadoptedtheprinciplessetoutfor“FAESACLASS”,involvingthestudent’sexperimentationwithmarketpractices,but also focusing on the student’s own role in the construction of knowledge, having been involved in the planning and execu-tionofactivities,writingreport,presentationofthelivedexperienceanddebatesonthepracticesexperiencedbyothergroups.It will be noticed that the change of posture of the teacher, with adoption of more dynamic teaching methods, allowingthestudenttobeanactoroftheprocess,facilitatetheachievementoftheobjectivesdefinedbytheteacherforthefutureprofessionalformation,besidesbeingabletoverifythatitisn’taspecificmethod,butthecombinationofvariousteachingtechniquesadaptedtothesituationexperienced,withelementsofgroupwork,theFlippedClassroom,theseminarandthetechnicalvisit
Planejamento integrado e nova prática entre cursos: a experimentação como processo de transformação de sujeitos e saberes
Authors: Ramos Parpaiola de Menezes Alessandra , Bravo de Souza Bonella Mirella
Published: July 2018

This paper presents the practical experience of a project that integrated two undergraduate courses, from FAESAUniversity Center’s different teaching units and areas: Journalism and Dentistry. The original objective was to make thefuturedentiststhefuturejournalists’clients,bythelatterhavingthetaskofdevelopingInternalCommunicationPlansforthe Dental Clinic where Dentistry Students develop a series of practical activities. However, within the perspective thatthese organizations are unique, since they are formed by individuals, and the understanding that interaction process andsocial organization are fundamental to establish plans’ production correct guiding diagnosis, it was not possible to limit theCommunication Products’ creation involvement. Dentists and journalists experimented together. There is a clear percep-tion that more than good posters, videos and photographs, the project resulted in the exchange of experiences, knowledge,respectandappreciationofthedifferentareas
Project Oriented Learning: Uma Aplicação à Disciplina de Sistemas Distribuídos
Authors: Roatti Howard
Published: July 2018

In 2017, an intervention was made in the various FAESA Centro Universitário courses, through 40 teachers ready fornewchallenges. The objective was: to apply in practice the three pillars of the FAESA Class (Personalization, Experimen-tation, Technology). They were instigated to remodel the classes of their disciplines, during the period, in search of impro-ving the teaching-learning process. In this report, we highlight the discipline called Distributed Systems that permeatesthecoursesofBachelorinComputerScience,BachelorinInformationSystems,TechnologyinAnalysisandDevelopmentofSystemsandTechnologyinComputerNetworks.Itisanimportanttheoretical-practicaldisciplinefortheformationof these courses, since it deals with a current topic of Information Technology. Applying a diagnosis in the class, it wasobserved the opportunity to apply the active methodology called Project Oriented Learning, which aims to learn about theperspective of projects, being based on some guidelines that allow the student to be the center of their learning, in a waythat builds their knowledge seeking solutions to theproblems that occur in the course, until the conclusion of the project.Thesuccessofthisworkisobservedintheapprovalratingoftheclassthatwasabove70%.