bluuebunny/crossref_metadata_2025 huggingface dataset:
Mathematical cardiology – history, status, prospects
Authors: Lishchuk V.A.
Published: December 2024

Mathematical models are used for therapy of acute heart failure, when activity of the central nervous system (CNS) is suppressed. Combinatory complexity CNS limits the use of mathematical models for therapy of chronic illnesses of heart. Goal: - the relationship definition between cardiovascular system (CVS) and CNS. A material. 101 research of animals. The intellectual control of 12000 patients. Methods. The AIBOLIT technology and LabVIEW. Results. Interdependence of functions and properties is determined by functions if the weak narcosis takes place. Interdependence of functions and properties is caused by properties if the deep narcosis takes place. Imitation on models has revealed a probable explanation: CNS increases the opportunities of systems with greater mistakes of regulation and reduces opportunities of systems with smaller mistakes of regulation. The conclusion. CNS does not control (if it is not the behavioral reactions) functional systems of blood circulation, but will organize interaction functional systems according to the principle of equilibration. It generates integrity: every system is necessary for all systems and all are necessary for every system. Therefore СVS together with contours CNS – is not a system, but organization This result allows overcoming «a damnation of complexity» - the basic obstacle on the way to mathematical cardiology. References to the results of clinical use are given
Informativeness of Doppler and B-mode ultrasound studies of neoplasms of the thyroid gland
Authors: Kovalenko M.M. , Kovtunenko D.V. , Kohut I.I.
Published: December 2024

The possibilify of thyroid gland disease diagnostics is presented. Comparative survey of usual and Doppler modes of ultrasonic analysis with cytological results verification was performed
Comparative analysis of breathing monitor designs
Authors: Kovalenko M.M. , Kutsyak O.A. , Lopata V.O. , Yanchiy R.I.
Published: December 2024

The article deals with issues related to the constructions of the respiratory monitoring devices (respiratory monitors). A comparison of its functionality is done. The using of certain respiratory monitor for diagnosis of sleep apnea in children of preschool age is emphasized
Application of the “cross-cutting problem” method to research mechanical characteristics of the receiving piezoceramic converter with split electrodes
Authors: Korzhyk A.V.
Published: December 2024

In a boundaries of hydro - electroelastics tasks the AFCh for mechanic fields of piezoelectric cylindrical transducer - reciver with disconnect electrodes are calculated and described. The solution are obtained for symmetrical electrical conditions. The full field, modes structure and modes AFCh and FFCh of mechanic fields is detected and described.
Stationary oscillations of the boundaries of the elastic layer, under the action uniformly distributed heat sources over the interval along the longitudinal coordinate
Authors: Bogdanov A.О.
Published: December 2024

The stationary thermoelastic vibrations analysis of the plain layer boundary is conducted. The problem is solved within the framework of disjoint thermoelasticity theory for the case when thermal sources concentrated in the layer -a £ x £ a (axis x is located along the half-space boundary). A method for solving of the indicated problem is developed, the calculation of the elastic characteristics is conducted and their analysis is executed in relation to remoteness from the source of excitation.
Sound emission by a cylindrical piezoceramic a transducer placed in a layer of sound-transparent material
Authors: Leyko O.H. , Pleskach M.H.
Published: December 2024

Based on a computational model in a form of an equivalent electromechanical circuit of a piezoceramic cylindrical transducer, placed in a layer of a sound transparent material, analytical expressions are obtained, describing the transducer’s sound field in its whole domain of existence. A calculating experiment is performed, allowing to analyze the mechanical impedance’s dependence on the frequency and the matching layer’s thickness. Some conclusions about the matching layer’s influence on the transducer’s sound field are made
Low power and high speed testing operating modes of Bluetooth devices
Authors: Sergiyenko P.Yu. , Savyn K.H. , Prokopenko Yu.V.
Published: December 2024

The aim of this work is discussing about peculiarities of radiofrequency characteristics measurement for Low Energy and High Speed Bluetooth devices. Measurement technique was implemented in the TC-3000C tester platform. Some practical measurements have been performed. A number of characteristics which give the opportunity to determine main radiofrequency parameters have been achieved
Interchannel interference and a method for assessing its impact to receive a signal
Authors: Sunduchkov A.K. , Ostrolutskaya Ye.A. , Fadeyeva Ye.A. , Sunduchkov K.S.
Published: December 2024

Inter-channel interference is a subject of investigation in this article. Article object is method creation for estimation inter-channel interference effect and its verification using specific examples. Research method consists of analytic model development and inter-channel interference impact for signal receiving calculation. Revealed that changing channel number from 24 to 96 with fixed transmit date rate can decrease noise to signal ration (ξ%) from 3% to 0.8% and at the same time increasing transmit data rate with all other parameters fixed leads to increasing ξ% from 0.8% up-to 4.5 % (e.g. 96 channels). Most significant noise reduction from 3% to 1.4%, W=196, occurs with increasing transmit data rate up to 48 Mbit/sec (QAM64) and increasing K=6 at the expense of increasing timing interval and guard interval simultaneously
A model of the space of thematic telegram channels based on contextual links
Authors: Puchkov Oleksandr , Lande Dmytro , Subach Ihor
Published: December 2024

The paper analyzes the existing models for describing the topology of the news web space, which reflect its division into coherent components such as its central part and peripheral areas, and proposes a new network model of thematic Telegram channels based on the idea of assessing the level of citation of individual information channels and taking into account direct links in messages from Telegram channels. It combines the content aspect of messages with the ability to take into account quantitative parameters. The study focuses on channels dedicated to cybersecurity and covers the first quarter of 2024. Based on the analysis of about 3,500 Telegram channels, more than 1,000 hyperlinked channels were identified and key areas of the information space, such as the communication zone, the communication core, and incoming and outgoing source segments, were outlined. The formed network is defined as a scale-free, structural network with self-similar properties and a power law distribution of node degrees, which confirms the applicability of the Pareto law to describe this space. A mathematical model is proposed that allows estimating the polynomial relationship between the volume of the communication area and the total number of sources. On the example of the CyberAggregator content monitoring system for information sources, a methodology for automated expansion of the database of target sources in the system is proposed, which provides dynamic enrichment of the list of information resources through the analysis of new contextual references in messages and an algorithm for its implementation.
Modeling of a Glow Discharge in a Coaxial System of Electrodes
Authors: Andriienko Olha Volodymyrivna , Sydorenko Serhii Volodymyrovych , Maikut Serhii Oleksiiovych , Tsybulskyi Leonid Yuriiovych , Kuzmichev Anatoly Ivanovich
Published: December 2024

Modeling of a glow discharge in a cylindrical coaxial system with dielectric ends of electrodes in the hydrodynamic drift-diffusion approximation was performed. Model parameters: outer cathode diameter 10 and 13 mm, anode diameter 2 mm, voltage 2800 V, gas temperature 300 K. pd ~ 1 Pa∙m, which corresponds to the left side of the minimum area of the Paschen curve for discharge ignition. Reactions of ionization of atoms by electron impact, generation and quenching of metastable atoms, elastic collision of electrons with atoms and elastic collision of ions, resonant recharging of ions, Penning ionization, as well as secondary ion-electron emission of the cathode were taken into account. The distribution of potential and concentration of charged particles in the interelectrode space, the density of ion and electron currents were calculated within the framework of a self-consistent problem, and the current-voltage characteristics for two modes of discharge - plasma and plasma-free - were presented. The effect of pd on the parameters and discharge mode is determined. The obtained results can be used in plasma technologies for modification of the internal surfaces of metal, hollow, long parts with a small cross-sectional size, that is, in conditions close to those complicated by the occurrence of a discharge.
Identification of Helicobacter pylori by polymerase chain reaction in saliva of pediatric patients with abdominal pain
Authors: Pérez Luz Elena Espinosa de los Monteros , Moreno Silvia García , Montaño Alfonso Galván , Rodríguez Araceli Contreras , Villegas Miguel Ángel De la Cruz , Roa María de Lourdes Suarez , García José Antonio Ibarra
Published: December 2024

Introduction: Helicobacter pylori is a Gram-negative bacterium, which has been linked to many gastrointestinal diseases and has been shown to be a causative of gastrointestinal cancer. Aim: The purpose of study was to identify Helicobacter pylori and its virulence factors (cagA and vacA) by PCR in saliva samples of pediatric patients with abdominal pain. Methodology: A total of 150 patients were included in this study, of whom 74 were females and 76 males. Sublingual saliva was collected, which was inoculated into urea Christensen broth for enrichment, and then PCR was used to amplify the glmM, ureA, cagA, and vacA genes. Results: The glmM gene was identified in 60 (40%) of the patients, while the ureA gene was identified in only 3 (2%). In those samples positive for glmM and ureA, the cagA gene was identified in 17 (28.3%) and vacA in 26 (43.3%). Conclusion: Our results show that it is possible to identify H. pylori in the saliva of pediatric patients with abdominal pain, and this was achieved through subcultures in enrichment media and the subsequent PCR of the glmM gene.
Utilizing computational approaches for the prediction of alpha-PPAR inhibitors from baobab (Adansonia digitata) against non-alcoholic fatty liver disease
Authors: AbdelGader Asia Awad , Al Bakry Afra M. , Elnasri Hind A. , Yahia Dawelbiet Abdelaal , Khaier Mona Abdelrahman Mohamed
Published: December 2024

Non-alcoholic fatty liver disease (NAFLD), a silent killer, lacks a specific treatment because there is currently no medication approved by the Federal Drug Administration (FDA) for its treatment. So, this serious situation requires the use of all resources to remedy this problem. Reducing triglyceridemia may be a promising strategy to lower the risk of NAFLD. So, the aim of the present study was to predict a new potential alpha-PPAR agonist as a drug for NAFLD from baobab fruit (Adansonia digitata) using molecular docking. Compounds from baobab fruit using the PubChem database were selected. Filtration of compounds was carried out using the Lipinski rules and ADME parameters. Then, Molecular Operating Environment (MOE) software was used to prepare these compounds as ligands for docking simulations. The 3D structure of the PPAR-alpha receptor was retrieved from the Protein Data Bank (PDB) database for docking simulations. The analysis of Adansonia digitata fruit showed the presence of 102 compounds using PubChem database. When filtering these compounds using the Lipinski rule, only 23 compounds were recorded with 0 violations. After docking through MOE software, one compound, namely the carbohydrate, D-Glucitol, 1, 3:2, 4-bis-O-((4-ethylphenyl) methylene) gave the least negative score of energy complex (about −8.2333 Kcal/mol) while the reference Pioglitazone drug gave a score of −7.7763 Kcal/mol. RMSD for the carbohydrate compound was 1.4141, while in the reference drug, it was 1.9589. The amino acid (THR) in the carbohydrate, D-Glucitol, is hydrophilic and neutrally charged at a physiological pH, suggesting better absorption, while in the reference drug, the amino acid (HIS) is hydrophobic at a physiological pH, potentially limiting the drug’s absorption. Additionally, the ADME properties of the carbohydrate showed good pharmacokinetic properties. The D-Glucitol, 1,3:2,4-bis-O-((4-ethylphenyl)methylene) compound, isolated from baobab fruit, shows promising potential as a novel agonist for the PPAR-alpha receptor responsible for non-alcoholic fatty liver disease (NAFLD). Further in vivo studies are necessary to investigate this compound’s therapeutic efficacy.
‘I don’t think I really realised how different the ‘new normal’ would be’—a qualitative study with cancer survivors to inform the development of survivorship centres
Authors: Barnhart Molly K. , Fong Eric , Botes Leon , Mulder Stella , Angell Blake , Jan Stephen , Tang Monica , Chua Boon
Published: December 2024

Many people experience a wide range of health and wellbeing issues after cancer, which could be addressed by various supportive care services. The purpose of this study was to identify the needs of cancer survivors and carers by exploring their personal experiences and access to these services to inform planning for a cancer survivorship centre in Sydney, Australia. Semi-structured interviews with patients who had completed active treatment and carers were conducted. A thematic analysis of the interviews was undertaken. Three main themes were identified from 40 interviews: access to support, supportive care services and irreversible impact on life. The access to support theme identified various facilitators and barriers that participants experienced in accessing services, particularly the lack of awareness about available services. The supportive care services theme highlighted a range of physical, psychological and social/practical services which were critical for addressing needs, and the importance of carers’ involvement with services. The irreversible impact on life theme underscored the permanent changes that participants experienced, both positive and negative, as a result of having cancer. The life-altering changes patients experience after cancer should be taken into consideration alongside service development. The study outcomes of patients’ and carers’ needs and experiences can influence the range of services and expertise considered to be integrated as part of cancer survivorship centres in similar settings. Implementing these recommendations may improve the uptake of supportive care services, self-empowerment, and patients’ wellbeing.
Optimizing Virtual Power Plants with Parallel Simulated Annealing on High-Performance Computing
Authors: Abbasi Ali , Alves Filipe , Ribeiro Rui , Sobral Joao Luis , Rodrigues Ricardo
Published: December 2024

This work focuses on optimizing the scheduling of Virtual Power Plant (VPP) to maximize social welfare and improve energy trading with the grid. Considering distributed energy resources (DERs) and battery lifespan limitations, we address the problem as a Mixed Integer Linear Programming (MILP) using a parallelized Simulated Annealing algorithm implemented on High-Performance Computing (HPC). This parallelization accelerates the exploration of the solution space, improving computational efficiency and enabling the system to handle larger networks of DERs and more complex scheduling decisions. The approach is evaluated through rigorous simulations, highlighting its effectiveness in reducing optimization time while maintaining high-quality solutions. The results demonstrate that our method significantly enhances the scalability of VPP scheduling and facilitates more responsive and efficient energy market participation, particularly in scenarios with stringent operational constraints and dynamic energy pricing. All experiments were conducted following a systematic pipeline, including hyperparameter optimization, to ensure that the configurations were optimized for efficient and effective performance.
Deep Learning Autoencoders for FFT-Based Clustering and Temporal Damage Evolution in Acoustic Emission Data from Composite Materials
Authors: Moustakidis Serafeim , Stergiou Konstantinos , Gee Matthew , Roshanmanesh Sanaz , Hayati Farzad , Karlsson Patrik , Papaelias Mayorkinos
Published: December 2024

Structural health monitoring (SHM) in Composite Fiber Reinforced Polymer (CFRP) structures is essential to ensure safety and reliability during service, particularly in critical industries such as aerospace and wind energy. Traditional methods of analysing Acoustic Emission (AE) signals in the time domain often fail to accurately detect subtle or early-stage damage, limiting their effectiveness. The present study introduces a novel approach that integrates frequency-domain analysis using Fast Fourier Transform (FFT) with deep learning techniques for more accurate and proactive damage detection. AE signals are first transformed into the frequency domain, where significant frequency components are extracted and used as input for an autoencoder network. The autoencoder reduces the dimensionality of the data while preserving essential features, enabling unsupervised clustering to identify distinct damage states. Temporal damage evolution is modeled using Markov chain analysis to provide insights into how damage progresses over time. The proposed method achieves a reconstruction error of 0.0017 and a high R-squared value of 0.95, indicating the autoencoder's effectiveness in learning compact representations while minimising information loss. Clustering results, with a silhouette score of 0.37, demonstrate well-separated clusters that correspond to different damage stages. Markov chain analysis captures the transitions between damage states, providing a predictive framework for assessing damage progression. These findings highlight the potential of the proposed approach for early damage detection and predictive maintenance, significantly improving the effectiveness of AE-based SHM systems in reducing downtime and extending component lifespan.
Study Thermal Behavior of White Light Emitting Diodes at Different Injection Electrical Current
Authors: Tran Trong-Nam , Nguyen Quang-Khoi
Published: December 2024

We study the thermal behavior of white LEDs by using the efficient stable thermal model. The sample of white LEDs with a correlated color temperature of 6500K is utilized in this study. The relation of forward current on the thermal behavior in encapsulanted volume is studied in both theoretical and empirical ways. Simulation and experimental results have indicated the advantages of the thermal model not only in studying thermal behavior but also in thermal management and packaging of white light-emitting diodes.
A Modified Acrylic Binder Used for the Graphite Negative Electrode in Lithium Ion Batteries
Authors: Feng Lianxiang , Chen Wenting , Hai Feng , Gao Xin , Ban Yuyu , Xue Weicheng , Yan Wentao , Yang Yunxiao , Li Mingtao
Published: December 2024

The water-based binder has the advantages of non-toxic, non-flammable, small odor and no pollution to the environment. However, there are problems such as low bond strength and poor battery cycle life of commonly used binders on the market. In this paper, the acrylic binder is modified. Acrylic acid/methacrylic acid, acrylonitrile, and octadecyl acrylate/octadecyl methacrylate are copolymerized at high temperature, and a new binder for graphite anode is successfully developed. The binder can significantly improve the affinity between the graphite anode and the electrolyte and the integrity of the graphite particles during the cycle, so that the battery has better electrochemical performance. During the charge and discharge cycle of 1 C, the graphite anode coated with PAANa as a binder was able to cycle 360 cycles and remain stable, far better than the 192 cycles of the commercial binder LA133. It is proved that the experimental formula has a certain commercial application prospect.
Assessing Senior High School Students’ Critical Thinking Skills on Global Warming in Samarinda
Authors: Syam Muliati , Efwinda Shelly , Putri Dinda Ar-Rizalah Pujie Rahmayana , Habibah Habibah , Hakim Abdul , Damayanti Puardmi
Published: December 2024

Global warming is a problem that has received attention from various countries because it can cause climate change accompanied by extreme natural disasters and threats to human health and survival on Earth. The problems of global warming will continue if not critically considered by the next generation. This study aimed to explore the level of critical thinking skills of high school students in Samarinda City and whether there are significant differences between the essential skills of thinking of public and private high school students and between male and female students. This research was an exploratory study using the survey method. The population in this study was all grade X high school students in Samarinda City, and a sample of 5 schools with details of 3 public and two private high schools totaled 274 students. The results showed that students' critical thinking skills were in the less crucial category, with the highest score on the likelihood and uncertainty analysis indicator of 63.89 and the lowest score on the problem-solving and decision-making indicator of 40.21. Public high school students demonstrated significantly higher critical thinking skills than their private school peers, while no significant difference was found between male and female students. The results of this study can be used as a reference for stakeholders to find out which indicators of critical thinking skills still need to be developed and take practical actions for the development of climate change education, especially in Samarinda. These findings highlight the need for targeted interventions to improve critical thinking skills in climate change education among high school students, particularly in Samarinda.
STEM-Based Physics Modules with CK-12 Simulations for High School Students: Development and Implementation
Authors: Nurlina Nurlina , M. Musdar , Hajati Kartika , Zulfiani Ulfa
Published: December 2024

Research has been conducted to develop STEM-based physics modules with CK-12 simulations for high school students. This study evaluates the STEM-based physics module’s validity, practicality, and effectiveness with CK-12 simulations for grade X students. The research employed research and development (R&D), utilizing the ADDIE model, which includes the stages of analysis, design, development, implementation, and evaluation. The study involved three expert validators and students from two schools to assess the module’s validity, practicality, and effectiveness. The participants comprised grades X MIA students from SMAN 1 Alu and X IPA students from MAN 2 Polewali Mandar. The validity of the developed physics modules, presented as a practical module, was assessed through expert validation, while practicality was evaluated using response questionnaires completed by students and teachers. Effectiveness was determined based on student learning outcome tests. The results indicate that the physics module was highly valid, with an overall validity score of 87.78%. Practicality was also rated highly, with scores of 90.29% from students and 99.00% from teachers. Furthermore, the module demonstrated effectiveness, as evidenced by student learning outcomes meeting the established criteria, with an effectiveness score of 79.17%. These findings suggest that STEM-based physics modules with CK-12 simulations can significantly enhance the quality of physics teaching and learning for high school students. In addition, this research should be explored for other topics.
Bioelectrical impedance analysis in monitoring dogs with myxomatous mitral valve disease: a preliminary study
Authors: Nisini Noemi , Birettoni Francesco , Porciello Francesco , Caivano Domenico , Corda Andrea
Published: December 2024

Bioelectrical Impedance Analysis (BIA) is a simple, non-invasive, real-time diagnostic technique routinely used in human clinical practice to assess body composition and hydration status. BIA raw parameters, particularly the Phase Angle (PhA), are gaining attention as markers of congestive states in humans, as body electrical impedance can be affected by variations in body water content. This study aimed to assess whether changes in BIA raw parameters in dogs with myxomatous mitral valve disease (MMVD) could be linked to disease progression. Nine Cavalier King Charles Spaniels (CKCS) with MMVD were prospectively recruited in a longitudinal study design. During the clinical follow-up of each dog, BIA raw parameters - Impedance (Z), Resistance (R), Reactance (Xc), and PhA - were recorded alongside NT-proBNP assessments at two time points. A reduction in PhA recorded at 50 kHz (P = 0.03) and an increase in NT-proBNP concentrations (P = 0.02) were observed in parallel with the progression of MMVD in this group of CKCS between the two time points. These preliminary findings suggest the potential clinical application of BIA in dogs, emphasizing the need for further research to determine whether PhA could serve as a valuable diagnostic and prognostic marker in cardiac diseases, as has already been established in human patients.
Automated material handling for inventory management system
Authors: Pinagapani Arun Kumar , G Abhishek , S Athipathi , R V Nithin Karthik , G B Pragatheesh
Published: December 2024

Industry 4.0 has improved productivity, facilitated work automation and simplified job augmentation. The rising deployment of robotic systems for warehouse automation is primarily responsible for the consistent growth of the Automated Material Handling Systems (AMHS) market. The emergence of Industry 4.0 has facilitated sustainability and ongoing technical breakthroughs. The design and construction of a material-handling prototype robot and monitoring system are described in this work. By reducing the need for humans, this system enables the effective transportation of commodities in the manufacturing area, inventory storage area, and warehouses. Robot mobility is the major emphasis of automated material handling systems, which combine mechanical and electrical components and link hardware and software. The adoption of this system is largely due to the ongoing developments in technologies like the Internet of Things (IoT), which allow for the easy integration of controllers with automated material handling equipment as well as the ability to control machines using a human-machine interface (HMI) by using an application with the additional specification of visualizing the management system by the user, which will retrieve data from the machine using the thing speak platform. Furthermore, continuous automatic staking and unstacking can be achieved in a loop using queuing technology. According to the weight of the materials, using HMI one can select the appropriate slots and place it, which can able to withstand the strain of the rack for a long duration of time.
Exploring the operational limits of a bolometric camera for thermoelastic stress measurementes using a photonic reference camera
Authors: Tribbiani Giulio , Truffarelli Tiberio , Zara Tommaso , Marsili Roberto , Gaspari Antonella , Fabbiano Laura , Rossi Gianluca
Published: December 2024

Image analysis-based measurement techniques are gaining popularity thanks to their ability of measuring different kinds of mechanical fields without interfering with the measurand. Thermoelastic Stress Analysis is a full field, non-contact technique that uses IR images and the principle of thermoelasticity to measure stress distributions. The low amplitude of the temperature variations and the high frequency excitations required, make it mandatory to use fast and expensive IR imaging systems. Using systems based on micro-bolometers instead of photonic sensor, could significantly reduce the cost of the instrumentation. The aim of this study is to understand how to tune the acquisition parameters of a bolometric thermal camera (i.e., the length of the thermal video) and set the right excitation frequency, to match the stress measurement obtained using a state of art photonic thermal camera. The stress concentration around the hole of a PVC sample was used to quantify the difference between the measurement results obtained by the two IR systems. The results showed how having more frames allowed to obtain more detailed maps of stress distribution and to reduce the gap between the bolometric camera and the reference one. The gap increased when the sample was tested with a frequency near the limit set by Nyquist’s theorem.
The development of measuring setup for electrical noise research in two-dimensional semiconductor structures for quantum Hall resistance standard
Authors: Wojciechowski Marcin , Hovorova Kateryna
Published: December 2024

This paper describes setups for measuring electrical noise in the frequency range from 10 kHz to 100 MHz of semiconductor structures made of new Dirac- materials - 2D-COF/MOF intended for the construction of quantum Hall resistance standard (QHRS). In measurement systems consisting of a spectrum analyzer working with a preamplifier, an input noise value of approximately 1 nV/√Hz at 100 kHz was achieved at a preamplifier gain of 400 V/V, and the noise figure (NF) of the entire measurement system was reduced to below 0.4 dB for higher frequencies, where this coefficient for the spectrum analyzer itself was of the order of 7 dB.
Comparative analysis of physical models of two-electrode conductivity cells with end and lateral liquid supplies
Authors: Stennik Oleksii
Published: December 2024

This article presents a physical model of a two-electrode conductivity cell with holes for filling located in the electrodes. The study investigates the non-uniformity of the current density distribution within the cell, caused by the presence of these holes. Using the finite element method (FEM), the electrical resistance bias of the cell is calculated and compared to an idealized model - a liquid column with specific geometric dimensions and a uniform field inside. A comparison of the resistance bias values between two models - one with end holes (located in the electrodes) and one with lateral liquid supply - is conducted. The results demonstrate that the resistance bias is highly dependent on the diameter of the holes and is mostly unaffected by their position. In most cases, the resistance bias of the model with holes in the electrodes is 3–6 % lower in absolute value compared to the model with side holes, assuming identical geometric parameters for the cell; meanwhile, the bias signs are opposite for these models.
Modified vehicle architecture for rapid prototyping
Authors: Sobotka Jan , Novák Jiří , Pinkava Jiří
Published: December 2024

A modern car is made up of a considerable amount of software running on many Electronic Control Units interconnected by communication infrastructure. Together, it creates a rigid system that is not easy to modify to run modified or custom code to implement new vehicle functions or collect scientific data. The paper presents a modified (electric) vehicle architecture that allows rapid prototyping of new software-oriented features. The architecture enables the control of a specific vehicle, the acquisition of arbitrary vehicle data, and offers an interface for communication with the driver. The solution is based on the hardware modification of the production car. The vehicle is equipped with an Advantech industrial computer, which creates an environment to run the prototyped software. All platform services are available through the REST API.
Pulse transit time estimation methods in a novel arterial simulator with variable pulse wave velocity
Authors: Filippi Federico , Fiori Giorgia , Bocchetta Gabriele , La Battaglia Vincenzo , Marini Stefano , Sciuto Salvatore Andrea , Scorza Andrea
Published: December 2024

Arterial stiffness is one of the key indicators of cardiovascular diseases, for which an early identification is crucial. Pulse Wave Velocity (PWV) is a widely used parameter to assess arterial stiffness. In clinical practice, it is common use to measure the PWV through the estimation of the Pulse Transit Time (PTT). In this study a comparison among three PTT estimation methods (peak-to-peak, tangent-secant, and cross-correlation) is proposed and applied to waveforms acquired on a novel arterial simulator able to change the stiffness of an arterial surrogate by varying the transmural pressure. After a measurement campaign carried out for several pressure values, the cross-correlation method has been confirmed to be the most robust, with uncertainties below 1.3 %. The operating principle of the arterial simulator has been confirmed since a change in transmural pressure of 25 kPa resulted in a change in PWV mean values of up to 1.7 m/s.
Soil chemistry analysis of the Orgéres site (La Thuile, AO - Italy) as a reference for archaeological interpretation
Authors: Ginepro Marco , Di Gangi Giorgio , Lebole Chiara Maria , Berto Silvia , Alchera Federica
Published: December 2024

Archaeology is the discipline that studies past human civilizations by collecting, documenting and analysing the traces left by the ancestors. The cross-contamination of different scientific fields such as geology, chemistry and physics endorsed a more accurate analysis of the archaeological sites. This work analysed samples from the archaeological site of Orgères, located near La Thuile (Valle d'Aosta) through the following methodologies: ICP-OES (Inductively Coupled Plasma-Optical Emission Spectroscopy), and CHNS analyser. Inside the site artefacts from the Roman era and structures from the 17th century were found. Results of four different areas were compared with samples taken outside the site. The main soil constituents were analysed through principal component analysis that allowed an in-depth study of the relationships between the samples and highlighted the variables that most influenced the observed relationships. By evaluating the data set, it has been possible to date the site and the activities that were carried out at the archaeological site.
From archaeological data to statistical analysis
Authors: Vacatello Federica
Published: December 2024

A doctoral research project, discussed in May 2022, has led to a greater understanding of the settlement dynamics that took place in the Mignone Valley over the long chronological period between the 6th and 11th centuries AD. This understanding has been achieved through the recent topographical investigations conducted in the context of the Mignone Valley. The research employed the ancient land uses, the road system and the exploitation of the rich mineral deposits of the ‘Monti della Tolfa’ as 'keys' for understanding the change, employing a statistical analysis method for the evaluation of the input data on which the overall assessment of the settlement dynamics in the area was based. The contribution that will be presented here is intended to analyse the type of statistical method that underlies the evaluation of the data collected and the preliminary results that have been arrived at through the realisation of particular spatial analyses calculated in a GIS environment on the data to which the logic-statistical process has attributed the greatest 'weight'.
Antimicrobial Susceptibility Pattern of Escherichia Coli (E-Coli) and Association of Infections in Immune-Compromised Cancer Patients
Authors:   Department of Microbiology, Sir Syed College of Medical Science for Girls, Karachi, Pakistan., Alvi Amber Yasmeen , Faisal Hina ,   Department of Microbiology, Sir Syed College of Medical Science for Girls, Karachi, Pakistan., Idris Azra ,   Department of Microbiology, Sir Syed College of Medical Science for Girls, Karachi, Pakistan., Yasmeen Maliha ,   Department of Microbiology, Sir Syed College of Medical Science for Girls, Karachi, Pakistan., Mushtaq Naseha ,   Department of Physiology, University of Karachi, Karachi, Pakistan., Siddiqui Hira Zafar ,   Department of Microbiology, Dow University of Health Sciences, Karachi, Pakistan.
Published: December 2024

Abstract: Background: Incidents of infections in immune-compromised patients are the cause of increased morbidity and mortality, this study aims to determine the microbial spectrum of Cancer patients with urinary tract infections, respiratory tract infections, and gastrointestinal tract infections.
Materials and Methods: This is a cross-sectional study conducted at a Layari General Hospital, in Karachi from March 2022 till May 2023. Patients from the oncology department were recruited in the study, Sputum, urine (mid-stream), or stool samples were collected for analysis. SPSS 22 was used to analyze the data. Effect modifiers were controlled through stratification. To assess the association between two variable mean values, a chi-square test was performed keeping the p-value ≤0.05 as significant.
Result: A total of 170 patients were included in the study, with a mean age of 36.8 ± 12.9 years and, a mean weight of 66.8 ± 14.2 kgs. Gender distribution indicated higher incidents in male patients with 95 (%) while 80 (%) females were included in the study. Escherichia Coli (E-Coli) was the most frequently reported organism 133 (78.2%) in Urinary tract infection, similarly Staphylococcus aureus was most frequently reported in Respiratory tract infection with 86 (50.4%), and Salmonella spp. and Shigella Spp. were reported with equal frequency in Gastrointestinal infection with 26 (15.6%) and 26 (15.6%) respectively. Conclusion: According to this study’s findings, urinary tract infections are the most frequently reported illness in immune-compromised patients, with Escherichia Coli (E-Coli) being the most widely reported microorganism. Broad-spectrum antibiotic overuse causes antibiotic resistance and increases illness rates.
Job Stress in Administrative Employees of Public Medical Institutes in Punjab, Pakistan
Authors:   Faculty of Management, Virtual University, Lahore, Pakistan., Rashid Ahmad , Arif Muhammad Maaz ,   Department of Medical Education, University of Health Sciences, Lahore, Pakistan., Mazhar Nauman ,   Department of Psychiatry, Services Institute of Medical Sciences, Lahore, Pakistan., Hassan Hammad ,   Department of Science of Dental Materials, University of Health Sciences, Lahore, Pakistan., Khalid Saira ,   Department of Science of Dental Materials, University of Health Sciences, Lahore, Pakistan., Bukhari Noreen Maqbool ,   Department of Community Medicine, Khawaja Muhammad Safdar Medical College, Sialkot, Pakistan.
Published: December 2024

Abstract: Background: Job stress arises when job demands exceed an individual’s coping capacity, leading to physical and psychological strain. Factors include excessive workload, tight deadlines, and lack of support.
Objective: To measure the job-related stress in the administrative employees in public medical institutes of Punjab.
Materials and Methods: This descriptive cross-sectional study took place at three public medical institutes in Punjab from Nov 2022 to July 2023, after the approval of the ethical review board. The data was collected through an interview-administered questionnaire. A well-structured questionnaire was devised using the Likert scale to collect the required data, with a score of 1 denoting no stress and 5 denoting extreme stress. A sample of 150 subjects was taken by purposive sampling technique. The collected data was entered and analyzed on SPSS software version 20.
Result: The mean age was 31.03±8.90. The overall mean job stress score reported in the present study was 3.35±0.59. The mean stress score regarding the nature of the task was 3.56±0.68, for the boss behavior was 3.30±0.36; regarding the organizational environment, it was 3.10±0.67; and for job-related tension, the mean stress score was 3.69±0.68, indicating that the participants were experiencing moderately to higher stress levels. Factors like workload, irritating noisy environment, lack of appreciation, and critical boss significantly contributed to higher stress levels.
Conclusion: The study indicated that most employees had moderate to high levels of job stress during work owing to several factors such as working overtime, unfamiliar duty, excessive criticism, heavy workload, and lack of authority.
Effect of Nasal Deviation on the Perception of Upper Dental Midline by General Dentists and Orthodontists
Authors:   Department of Orthodontics, Margalla Institute of Health Sciences, Rawalpindi, Pakistan., Haider Ittrat , Shaheed Mehwish ,   Department of Orthodontics, Margalla Institute of Health Sciences, Rawalpindi, Pakistan., Shaukat Yusra ,   Department of Orthodontics, Margalla Institute of Health Sciences, Rawalpindi, Pakistan., Tahir Wardah ,   Department of Orthodontics, Margalla Institute of Health Sciences, Rawalpindi, Pakistan., Arshad Hafiz Muhammad Talha ,   Department of Orthodontics, Margalla Institute of Health Sciences, Rawalpindi, Pakistan., Ilyas Kausar ,   Department of Orthodontics, Margalla Institute of Health Sciences, Rawalpindi, Pakistan.
Published: December 2024

Abstract: Background: Establishing the relationship between dental and facial midlines aids in achieving the desired dentofacial aesthetics post-orthodontic treatment.
Objective: The primary objective of this study was to assess the effect of nasal deviation on the perception of maxillary dental midline by the orthodontic practitioners and general dentists. Secondary objectives were to see if there was any significant difference between the perception of female and male participants, and orthodontic practitioners and general dentists.
Materials and Methods: This cross-sectional study was conducted in Margalla Institute of Health Sciences (MIHS) Rawalpindi after obtaining ethical approval. Morphed frontal smiling photographs of a female subject were used to assess the perception of the participants. The nasal midline was progressively altered at every 1 mm from 0 mm to 4 mm towards left while keeping the upper dental midline on. The data were analyzed by using SPSS version 26.0. P-values of < 0.05 were taken as significant.
Result: Out of 200 study subjects, 106( 53%) were general dentists and 94 (47%) were orthodontic practitioners. There was a significant increase in the misperception of upper dental midline with an increase in the nasal deviation. There was no statistically significant difference found between the findings of general dentists and orthodontists, with the exception of one image (Image 2), for which the p value was 0.017. Statistically, no significant difference was observed between male and female participants’ results.
Conclusion: The nasal deviation affects dental midline perception, with only minor differences between general dentists and orthodontists underscoring the necessity for comprehensive facial evaluations in dental practice to ensure accurate aesthetic and functional assessments.
Sudden Unilateral Loss of Vision in a Young Girl: A Case Report
Authors:   Department of Pediatric, Azra Naheed Medical College, Lahore, Pakistan., Saeed Mahnoor , Al-Ali Jamilah Hadi ,   Department of Pediatric, Batterjee Medical College, Khamis Mushait, Saudi Arabia., Saeed Muhammad ,   Department of Neurology, Armed Forces Hospital Southern Region, Khamis Mushait, Saudia Arabia., Al-Sumaili Mohammad ,   Department of Neurology, Armed Forces Hospital Southern Region, Khamis Mushait, Saudia Arabia., Al-Asmari Badriah ,   Department of Pediatric Medicine, Armed Forces Hospital Southern Region, Khamis Mushait, Saudia Arabia.
Published: December 2024

Abstract: A casual association seems to exist between the onset of intracranial hypertension (IH) and growth hormone (GH) therapy. Children receiving GH treatment, if they complain of headaches or visual difficulties, should undergo detailed ophthalmological evaluation. Herein, we report a young girl who was receiving GH treatment for idiopathic short stature, and due to the adverse effects of GH, she developed intracranial hypertension, as a result of which, she developed unilateral blindness.
El uso del sistema láser de diodo infrarrojo en la retracción gingival para la toma de impresión: una revisión de la literatura
Authors:   , Ponceca Contreras Silvia
Published: December 2024

La presente revisión bibliográfica tuvo como objetivo describir sobre el uso del sistema láser de diodo infrarrojo para la técnica de retracción gingival lo cual ayudara en la impresión en prótesis fijas. Métodos: La búsqueda se realizó en las siguientes fuentes de datos disponible tales como: MEDLINE vía PubMed, SCOPUS, Science direct y SciELO con las palabras claves: laser diode, Gingival Retraction techniques, dentistry: desde el año 2003 hasta septiembre del 2023. Resultados: Se encontraron 93 artículos de los cuales se incluyeron 14 publicaciones para su revisión. Los sistemas láser de diodo infrarrojo son eficientes en la técnica retracción gingival, se han descrito una buena hemostasia, menor tiempo de trabajo, descontaminación del surco gingival, menor recesión gingival, confort para el paciente y dolor posoperatorio mínimo. Conclusiones: El sistema láser diodo infrarrojo de acuerdo a la revisión de la literatura actualizada, se presenta como una buena alternativa de uso para la retracción gingival en la toma de impresión, proporcionando una base para la aplicación clínica de esta técnica que puede contribuir al éxito en prótesis fija.
Asociación entre los conocimientos sobre SARS-COV-2 y la identificación del mecanismo de acción de las vacunas disponibles en Perú contra SARS-COV-2 en estudiantes de la Facultad de Medicina Humana de la Universidad Científica del Sur
Authors:   , Macha Quispe Ashley Johanna , Ferri Perez Renato
Published: December 2024

Introducción: Cuando se dio el SARS-Cov-2 la sociedad no estaba preparada para una pandemia de tal magnitud es por eso que debido desinformación se fue creando una gigantesca nube de falsas noticias lo cual preocupo y alarmó a la población, por eso el rol de nosotros como parte del sistema de salud influimos en la promoción de la vacunación y del SARS-Cov-2 dentro de la sociedad. Objetivos: Determinar si existe asociación entre conocimientos sobre Sars-Cov-2 con la capacidad de identificar el mecanismo de acción de las vacunas disponibles en el Perú contra SARS-Cov-2 dentro de estudiantes de la facultad de medicina humana. Metodología: Estudio transversal, analitico y observacional, como población se tomó a los matriculados del ciclo lectivo 2023 que fueron los alumnos de la facultad de medicina humana de la Universidad Científica del Sur. Resultados: En este estudio participaron 206 estudiantes de Ciencias de la Salud. El conocimiento sobre SARS-CoV-2 fue evaluado con una escala de 14 preguntas y el promedio fue de 10.81 y sobre vacunas se utilizó una escala de 5 vacunas utilizando las que estaban disponibles en el Perú en ese entonces y el promedio fue 2. Discusión: Por consiguiente, el modelo ajustado y especialmente en estratos de sexo masculino y el antecedente de no haber sufrido COVID-19 se contrasto que un mayor conocimiento sobre el virus se asocia con un mayor conocimiento sobre los mecanismos de acción de las vacunas contra el SARS-Cov-2. Esto resalta la importancia dentro de la carrera de medicina humana de impartir una educación enfocada en el realce de conocimientos sobre SARS-Cov-2 y sobre los mecanismos de acción de las vacunas.