bluuebunny/crossref_metadata_2025 huggingface dataset:
Insulin secretion, sensitivity, and kidney function in young persons with type 2 diabetes
Authors: Bjornstad Petter , Ji Choi Ye , Platnick Carson , Gross Susan , Narongkiatikhun Phoom , Melena Isabella , Remmers Lauryn , Baca Mayra , Schutte Grant , Dobbs Tyler , Vigers Tim , Pyle Laura , Driscoll Lynette , Tommerdahl Kalie , Kendrick Jessica , C Looker Helen , Dart Allison , Cherney David , H van Raalte Daniel , Srivastava Anand , Li Luping , Prasad Pottumarthi , Saulnier Pierre , G Nelson Robert , J Johnson Richard , J Nadeau Kristen
Published: December 2023

Objective: β-cell dysfunction and insulin resistance magnify risk for kidney injury in type 2 diabetes. The relationship between these factors and intraglomerular hemodynamics and kidney oxygen availability in youth with type 2 diabetes remains sparsely explored. Research Design and Methods: Fifty youth with type 2 diabetes (age: 16±2 years, diabetes duration: 2.3±1.8 years, 60% female, HbA1c: 6.4 [5.9, 7.6]%, body mass index (BMI): 36.4±7.4kg/m2, urine albumin-to-creatinine ratio (UACR): 10.3 [5.9, 58.0]mg/g), 21 controls with obesity (OC) (age: 16±2 years, 29% female, BMI: 37.6±7.4kg/m2), and 20 controls in normal weight category (NWC) (age: 17±3 years, 70% female, BMI: 22.5±3.6kg/m2) underwent iohexol and p-aminohippurate clearance to assess glomerular filtration rate (GFR) and renal plasma flow (RPF), kidney MRI for oxygenation, hyperglycemic clamps for insulin secretion (acute c-peptide response to glucose [ACPRg]) and disposition index (DI, x103 mg/kg lean/min), and dual-energy X-ray absorptiometry for body composition. Results: Youth with type 2 diabetes exhibited lower DI (0.6 [0.0, 1.6] vs. 3.8 [2.4, 4.5] x103 mg/kg lean/min, p<0.0001) and ACPRg (0.6 [0.3, 1.4] vs. 5.3 [4.3, 6.9] nmol/L, p<0.001), and higher UACR (10.3 [5.9, 58.0] vs. 5.3 [3.4, 14.3]mg/g, p=0.003), and intraglomerular pressure (77.8±11.5 vs. 64.8±5.0 mmHg, p<0.001) compared to OC. Youth with type 2 diabetes and OC had higher GFR and kidney oxygen availability (relative hyperoxia) than NWC. DI associated inversely with intraglomerular pressure and kidney hyperoxia. Conclusion: Youth with type 2 diabetes demonstrated severe β-cell dysfunction that associated with intraglomerular hypertension and kidney hyperoxia. Similar but attenuated findings were found in OC youth.
Análisis Pseudo tridimensional de una estructura porticada de tres pisos en la ciudad de Chanchamayo
Authors:   Universidad Nacional Intercultural Juan Santos Atahualpa, Chanchamayo, Perú., Rupay Vargas Marcos Josue , Lopez Yarango Jorge Santiago ,   Universidad Nacional Intercultural Juan Santos Atahualpa, Chanchamayo, Perú, Gonzales Huaman Carlos Bryan ,   Universidad Nacional Intercultural Juan Santos Atahualpa, Chanchamayo, Perú, Casimiro Minaya Juan Pablo ,   Universidad Nacional Intercultural Juan Santos Atahualpa, Chanchamayo, Perú
Published: December 2023

El presente artículo científico consiste en calcular las deformaciones y desplazamientos por cada entrepiso, hallar las fuerzas en cada pórtico, encontrar las cortantes en cada uno de los pórticos y comprobar los resultados mediante el software estructural Etabs. La metodología aplicada es de carácter cuantitativo, el proceso de solución y los resultados fueron descritos por fórmulas matemáticas, además se agregó los apuntes de clases de la asignatura de Análisis Estructural II brindada en la Universidad Nacional Intercultural de la Selva Central Juan Santos Atahualpa, donde se pudo extraer pasos para lograr desarrollar el ejercicio planteado por los integrantes que desarrollan este artículo, se considera también los criterios y enseñanzas brindadas por el ingeniero a cargo de la asignatura. Para concluir, se tiene planeado plasmar un esquema del desarrollo del ejercicio, donde se va visualizar el método utilizado para el desarrollo del artículo de investigación. Los resultados se van a plasmar a detalle para que pueda ser interpretados por los lectores de este artículo científico. En conclusión, se observará los resultados que se obtuvo del ejercicio aplicativo, hechos manualmente y comparados con el software Etabs para tener una comparación sobre lo resuelto manualmente.
Isoprene and its Overall Impacts: Review
Authors: YK Lahir
Published: December 2023

A clean environment is a suitable medium for providing requirements that sustain the organisms living therein. Hence, it is a ‘natural-store house’ to receive and provide the metabolic needs of the biotic and abiotic systems. It also accomplishes the crucial geochemical cycles that maintain their appropriate balance. The metabolites may be quantitatively and qualitatively meagre but cause good and bad impacts. The organisms also contribute to these metabolites. The anthropogenic interference a prime causes of environmental disturbances and renders the environment unsuitable. Isoprene is one of the biogenic and abiogenic volatile organic compounds prominently present in the lower troposphere. Normally, this volatile compound interacts with ozone, hydroxyl and oxides of nitrogen and causes depletion of ozone. Trees that combat unfavorable fluctuations in environmental parameters like high winds, tornadoes, extreme temperature, drought (a complex impact), flood, wild fires, and deficiency of nutrition, experience the influence of isoprene. Mostly the developing countries encounter poor air quality that contains particulate matter, pollutants resulting in respiratory illness, cardiovascular and cancerous ailments. The presence of volatile organic components in human exhaled air indicates their metabolic or the ambient environmental origin. The endogenous organic volatile compounds present in human breath are the biomarkers for the pathophysiological conditions and are of clinical and biomedical significance, specifically during non-invasive estimations. Although, isoprene has attracted researchers but its pathophysiological impacts need more investigations, hence, this presentation to evaluate the effects of isoprene in biosphere.
Multimetallic Approach of Essential and Toxic Residual Elements in Placenta, Amniotic Membrane, and Umbilical Cord of Human Beings
Authors: Veas Isabel Pizarro
Published: December 2023

The environmental impact of metallic pollutants due to the overload of essential metals and the enrichment of heavy metals on the biological species and human beings, it is determined by the genetic patrimony and environmental factors. Feeding, quality of water consumption, quality of the air, habits and geological ambient. Due their volcanic soil origin and its mining growing activity, the ecosystem of the region of Antofagasta in Chile has seen increased their industrial ecology complexity at cost of its natural ecosystems. In this work it is assumed that the human placenta and their related tissues such as amniotic membranes and umbilical cord, can be “good bio – markers tissues” to the metal exposure. Li, Cr, Mn, Fe, Co, Ni, Cu, Zn, Cd, Hg, Pb, As and Se residuals concentrations were determined in amniotic membranes, placentas and umbilical cords of newly normal born and newly born with congenital anomalies of mothers from region of Antofagasta in Chile. Significant enrichments in Li, Cr, Ni, Hg and Pb they were found in placentas and umbilical cords of the group of malformed newly born (MB), regarding the same tissues of the normal newly born group (NB). The values of the metal concentration quotients among the tissues, metal in cord / metal in placenta can be considered as an index of the transfer of heavy metals toward the foetus. The application of clustering techniques to the association among the metal concentration results regarding the demographic variables, allowed to infer that in general, the distribution of the metals in the studied tissues seem to be quite independent of the demographic variables considered, that which implies that more traverse factors that those discriminated against with these variables would be more important for the risk of developmental disorder due the metals and metalloids exposure in the region of Antofagasta.
Evaluation of Synergistic Formulation Extract of Traditional Contraceptive Plants for Acute Oral Toxicity
Authors: Kadam Asha Bhausaheb
Published: December 2023

In folk medicine, certain plants are used to prevent pregnancy. The purpose of the study was to evaluate the synergistic formulation of conventional contraceptive herb’s acute toxicity. Acute toxicity refers to a negative change that happens right away after exposure to a drug. Using OECD-423 recommendations, the acute toxicity of crude oil and its aqueous extract was assessed after oral administration to female mice. 2000mg/kg of a high extract was provided as a single dosage, and the effects on mortality, behavioural pattern, and spontaneous movement (Locomotor activity) of the body were assessed. The upper limit of 2000 mg/kg did not result in any fatalities. The results indicated that both aqueous and petroleum ether had LD50 values more than 2000 mg/kg. Consequently, plant synergistic extract is safe. This research can be used to determine the dose structure for future experiments evaluating the efficacy of natural contraceptive herbs.
Molecular-Engineered Nanoparticle’s Intensive Use in Nanotechnology Challenges like Nanotoxicity and Breakthrough Opportunities
Authors: Devi Salam Himika
Published: December 2023

This critical review focuses on Engineered nanoparticles (ENPs) types, properties, toxicities, applications, and future scopes. ENPs are specially designed chemical substances or materials with a particle size between 1 and 100 nm in at least one dimension, while the term Engineered nanomaterials (ENMs) is used collectively for ENPs and nanostructured materials. They can be classified into different classes based on their properties, shapes, or sizes. The different groups include fullerenes, metal NPs, ceramic NPs, and polymeric NPs. NPs possess unique physical and chemical properties due to their high surface area and nanoscale size. NPs like carbon nanotubes (CNTs), quantum dots (QDs), fullerenes, nanocomposites, metal-oxide nanoparticles (TiO2, ZnO, and iron oxides), and fibrous nanomaterials (NMs). Exposure to such ENP increases as nanotechnology advances, though it is an emerging field with a wide range of applications as an interdisciplinary, integrated science with huge potential. Aims to present a comprehensive review of nanotoxicity to human health and impact on the environment, future aspects breakthrough opportunities. Nanowaste as a new and challenging research topic is also highlighted. NPs’ intensive use, persistence, and retention in the environment need to evaluate nanogenotoxicity to humans and other organisms. ENMs used in therapeutic targeted drug delivery, their toxicokinetic, surface chemistry, mechanism of cellular interactions, effect on chromosomes, and DNA started being studied by researchers, however, not fully understood. Nano genotoxicity assessment should be done thoroughly following regulatory guidelines in order to safeguard humans from its harmful effects like cancer and reduce fertility. ENM retention time in the environment should be traced keeping in mind Eco nanotoxicity, bioaccumulation, and biomagnification in aquatic and forest ecosystems. The unique properties of NPs can be utilized fully by knowing all useful characteristics for breakthrough inventions in health care, cancer treatment, anti-aging (longevity), aeronautics, illuminating diodes, nanofertilizers and Artificial Intelligence (AI)-powered robotics for noble innovations for human use. Finally, the challenges of nanowaste management and gaps in breakthrough opportunities are highlighted to reflect the need for more serious action and advancement in nanoscience with novel inventions.
Cannabidiol Decreases Neuropathic Pain in Mice by Release of Opioid Peptides
Authors: MGM Castor
Published: December 2023

Background: More than 100 phytocannabinoids have already been identified present in varying percentages of composition in the various plants of the genus Cannabis, including cannabidiol (CBD). Some evidences have demonstrated the effectiveness of CBD in treating neuropathic pain. We evaluated the participation of the opioid system in peripheral antinociception induced by the administration of CBD in the face of neuropathic pain induced by constriction of the sciatic nerve. Methods: Neuropathic pain was induced with the constriction of the sciatic nerve while the nociceptive threshold was measured using the pressure test of the mice paw. All drugs were administered by intraplantar injections in the right hind paw of mice. Results: Bestatin, an inhibitor of the enzyme aminopeptidase N, which degrades opioid peptides, potentiated the antinociceptive effect of the lowest administered dose of CBD (5 μg/paw). The antinociceptive effect of CBD was reversed by the administration of naloxone, a non-selective antagonist for opioid receptor. The selective antagonist for μ opioid receptor, clocinnamox, reversed the antinociceptive effect of CBD. Naltrindole, a selective antagonist for δ opioid receptors, and nor-binaltorphymine, a selective antagonist for κ opioid receptors, partially reversed the antinociception induced by CBD. Conclusions: Our data suggest the participation of the opioid system in CBD-induced peripheral antinociception in the model of neuropathic pain induced by sciatic nerve constriction in mice. Keywords: Cannabidiol; Neuropathic Pain; Peripheral Antinociception; Opioid System
Pre-Clinical Evaluation for Anti-Inflammatory, Antioxidant and Antibacterial Potential of Boswellia seratta
Authors: T Satapathy
Published: December 2023

Objective: The present study was undertaken to evaluate the anti-inflammatory, anti-oxidant and antibacterial potential of Boswellia serrata extract. Methods: Antioxidant activity was determined using DPPH, Hydroxyl, and Total antioxidant capacity and nitric oxide radical scavenging activities. Anti-inflammatory activity was determined using hyaluronidase enzyme inhibitory assay in which Indomethacin was taken as a reference drug. Agar diffusion was used as a test for antibacterial activity. Grampositive (Staphylococcus aureus) and gram-negative (Escherichia coli) bacteria were chosen for the experiment. As a standard medication, ciprofloxacin was used. Results: Test sample free radical scavenging activity was assessed at 10μg, 50μg, and 100μg concentrations. Results demonstrated dose-dependent inhibition (75.90% at 100μl concentration). Results for hydroxyl radical scavenging activity were compared to Ascorbic acid at concentrations of 10μl, 50μl, and 100μl. Hydoxyl radical scavenging activity was dosedependent like free radical scavenging activity. Inhibition was highest at 100μl concentration (89%), while standard medication Ascorbic acid demonstrated 94.84%.Sample concentrations (10μg, 50μg, and 100μg) were tested for nitric oxide scavenging activity, with maximal scavenging reported. Obtained 87.64% at 100μl concentration, compared to 89.73% for reference medication BHA. Hyaluronidase enzyme inhibition testing results show 84.84 % inhibition at 100μl concentration (Maximum inhibition). Conclusions: Boswellia serrata standard extract shows dose-dependent free radical scavenging and hyaluronidase inhibitory activities.
IMPLEMENTASI SISTEM MUTU INTERNAL UNTUK MENINGKATKAN MUTU PENDIDIKAN DASAR
Authors: Abdullah Dede , Pasaribu Rhendivan , Ninda A Anggistia , Dominico P S Claudi
Published: December 2023

To implement state education goals, internal quality assurance is carried out in relation to national education standards. Internal quality is now applied not only to higher education, but also to primary and secondary education. We continue to ensure and lead educational quality assurance and compliance in primary and secondary school units. The aim of this research is to determine and describe the implementation of the internal quality system cycle. The techniques used in data collection are: Observation, interviews, documentary research. The results of the research show that the quality improvement steps implemented at Bawamai Pontianak Elementary School are in accordance with the SPMI cycle steps including: First, school self-evaluation based on education quality certificates; second, a plan to improve quality through the formation of a quality committee and analysis of the results of the Kermbali School self-evaluation; Implementation of quality improvement, fourth, evaluation of follow-up and results of quality improvement after quality improvement, and fifth, return to next year's quality plan. The results of implementing internal quality assurance influence a more innovative learning process, student and school performance, satisfaction and success of internal and external customers. Eight national education standards.
Investigation of the Complex Formation Process of Lead (II) with Natural Macromolecular Organic Substances (Fulvic Acids) by the Solubility and Gel Chromatographic Methods
Authors:   IvaneJavakhishvili Tbilisi State University R.Agladze Institute of Inorganic Chemistry and Electrochemistry, 11 Mindeli St., Tbilisi0186, Georgia, Makharadze Tamar , Makharadze Giorgi ,   IvaneJavakhishvili Tbilisi State University, 3 Ilia Chavchavadze Ave., Tbilisi0179, Georgia
Published: December 2023

Fulvic acids are one ofthe most important ligands, governingthe geochemical cycling of metals in the environment. The objective of the work was to investigate the complex formation process between fulvic acids and Pb(II).The complex formation processwas studied by the solubility and gel chromatographic methods at pH 5.0 and 8.0.
Design, Synthesis and Biological Activity of the 4-Thioquinoline Derivative
Authors:   Zaporizhzhia National University, Faculty of Biology, 66, Zhukovs’ky St., Zaporizhzhia, 69095, Ukraine, Bohdan Anna , Romanenko Yanina ,   Zaporizhzhia National University, Faculty of Biology, 66, Zhukovs’ky St., Zaporizhzhia, 69095, Ukraine, Zavhorodnii Mikhail ,   Khortytsia National Academy, 59, Naukovemistechko St., Khortytsiaisland, Zaporizhzhia, 69017, Ukraine, Kornet Maryna ,   Zaporizhzhia National University, Faculty of Biology, 66, Zhukovs’ky St., Zaporizhzhia, 69095, Ukraine,   Institute of Organic Chemistry and Macromolecular Chemistry, Heinrich-Heine-University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany, Shupeniuk Vasyl ,   VasylStefanykPrecarpathian National University, 57, Shevchenko St., Ivano-Frankivsk, 76018, Ukraine, Nepolraj Amaladoss ,   Department of Chemistry, PGP College of Arts and Science Paramathi, Namakkal, Tamil Nadu, India, Klimova Olena ,   Zaporizhzhia National University, Faculty of Biology, 66, Zhukovs’ky St., Zaporizhzhia, 69095, Ukraine, Brazhko Oleksandr ,   Zaporizhzhia National University, Faculty of Biology, 66, Zhukovs’ky St., Zaporizhzhia, 69095, Ukraine
Published: December 2023

One of the promising areas in the creation of bioregulators is the modeling of compounds that combine several pharmacophores. The design of new highly efficient and low-toxic cytoprotectors is largely based on the derivatives of nitrogen-containing heterocycles, and quinoline plays a significant role among these compounds. The researchers evaluated the toxicity of the tested compounds in silico, in vitro, and in vivo, which allowed determiningseveral factors that affect the level of toxic action of 4-thioquinoline derivatives and the direction of non-toxic substances in this sequence. The studied 4-thioquinolines showed a moderate antiradical action in the experiment, inferior to the reference antioxidant Acetylcysteine. The most active compounds are 7-chloro-4-thioquinoline derivatives with propanoic acid residues in the 4th position. 2-(7-chloroquinolin-4-ylthio)propanoic acid and sodium salt of 2-amino-3-((7-chloroquinolin-4-yl)thio)propanoic acid showed the most promising results and their antioxidant action was higher than Tiotriazolin (the comparator) by 27 % and 41 %, respectively. The studied compounds showed a protective effect under H2O2-induced oxidative stress against male sperm according to the main indicators of sperm fertility. It was found that the compounds withresidues of succinic acid, cysteamine, or cysteine in the molecule structure are not inferior to reference drugs. On average, 2-((7-chloroquinolin-4-yl)thio)succinic acid and 2-((quinolin-4-yl)thio)ethanaminedihydrochloride exceeded the comparison drug Acetylcysteine and were on a par with the effect of Ascorbic acid.
Spontaneous Polymerization of 4-Vinylpyridine Monomer on Micron-Sized Mica Platelets
Authors:   Centre de Recherche Scientifique et Technique en Analyses Physico-Chimiques. BP 384, zone industrielle 42004 Tipaza, Algérie, Dergal Fayçal ,   Laboratoire de Catalyse et Synthèse en Chimie Organique, Faculté des Sciences, Université de Tlemcen, BP 119, 13000 Tlemcen, Algérie, Lerari Djahida ,   Centre de Recherche Scientifique et Technique en Analyses Physico-Chimiques. BP 384, zone industrielle 42004 Tipaza, Algérie, Bachari Khaldoun ,   Centre de Recherche Scientifique et Technique en Analyses Physico-Chimiques. BP 384, zone industrielle 42004 Tipaza, Algérie
Published: December 2023

In this study, we reported the spontaneous polymerization of two composite materials based on P4VP and mica at two different ratios, 4VP/mica/R=5 and 4VP/mica/R=10, noted as P4VP5@mica and P4VP10@mica, respectively. The obtained composites were characterized using thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). The polymerized P4VP on the inorganic surface has potential interest for the modification of the interfacial properties of the mica.
MEDIATION OF PERCEIVED VALUE ON THE EFFECT OF SERVICE QUALITY AND OBJECT UNIQUENESS ON CUSTOMER SATISFACTION AT TENAYAN RAYA AGROTOURISM PEKANBARU
Authors: Putri Amanda Dwi , Miran Ikas
Published: December 2023

This research aims to analyze the influence of service quality and object uniqueness on perceived value and consumer satisfaction and then to analyze the role of perceived value as a mediator on the influence of service quality and object uniqueness on consumer satisfaction at Tenayan Raya Agrotourism. This research quantitative research by distributing questionnaires to visitors of the Tenayan Raya Agrotourism. The sample for this research consisted of 142 respondents. Data analysis uses the Structural Equation Model (SEM) with AMOS. The research results show that service quality has a positive and significant effect on perceived value, object uniqueness has an insignificant effect on perceived value, service quality has a positive and significant effect on consumer satisfaction, and object uniqueness has an insignificant effect on customer satisfaction. Then, perceived value is able to mediate the influence of service quality on consumer satisfaction, but it can’t be able to mediate the influence of object uniqueness on customer satisfaction.
BEHAVIORAL ANALYSIS OF VEGETARIANS: THE ROLE SOCIAL MEDIA BUMI RESTO AND FORTUNATE COFFEE PEKANBARU
Authors: Irawati Irawati , Triyonowati Triyonowati
Published: December 2023

This study aims to describe the behaviour of vegetarians in using social media, to serve vegetarians and non-vegetarians. Bumi Resto and Fortunate Coffee with a universal happiness mission can help everyone to be healthy and happy. The research design is a combination of qualitative and quantitative, managers and visitors as respondents. Data analysis with interactive model, data validity with triangulation validation and member check. The results showed that the behavior of vegetarians with three models, the first behaviour change, namely vegetarianism of conditioning or habits, second behavior change understanding, and third behaviour by giving concrete examples. The behaviour of a person with knowledge, attitudes, or traditions of life. The role of social media adds business value in supporting product sales that are promoted and become a development trend.
BUSINESS ETHICS: A REVIEW OF IMPORTANT VALUES IN THE BUDDHIST PERSPECTIVE
Authors: Sonika Sonika , Irawati Irawati
Published: December 2023

This article approaches the Buddhist moral (sila) to business ethics, with moral values of innate sense of moral dread and shame (hiri-ottappa) as the basis for doing business. Buddhist philosophy originates with the teachings of the Buddha (588 BCE). Every human has free will to think, speak, and act ethically by undoing evil, cultivating goodness, and purifying the mind as the core of the Buddha Dharma. This literature review emphasizes Buddhist virtues with a naturalist focus, the value of compassion for all life; humanist, human values; and altruist, caring values to benefit others. The impact of these values (Tzu Kuang, 2015) is called the ten globally shared, which are build upon the equality and dignity of humanity by mutual co-existence, the honor, riches, joy, serenity, awakening, ownership, achievements; prosperity and success are shared mutual.
EMPLOYEE ENGAGEMENT, COMPENSATION, AND WORK DISCIPLINE ON EMPLOYEE PERFORMANCE
Authors: Jauhari Ahmad , Pribadiyono Pribadiyono
Published: December 2023

The issue addressed in this research focuses on the declining employee performance, which is indicated by factors such as employee engagement, compensation, and work discipline. The research was conducted at CV. Asia Paramitha, a company engaged in the distribution of agricultural pharmaceutical products in Kediri Regency. The population consisted of 89 respondents, and a sample of 53 individuals who met the criteria was obtained using purposive sampling. Data collection was conducted through a survey with a questionnaire as the primary instrument. The data were analyzed using inferential statistical methods, specifically multiple linear regression analysis to test hypotheses. The research results indicate that employee engagement has a partial, positive, and significant influence on employee performance. Compensation, on the other hand, has no significant influence on employee performance when considered separately. Work discipline, when examined separately, has a partial, positive, and significant influence on employee performance. Simultaneously, employee engagement, compensation, and work discipline have a positive and significant impact on employee performance at CV. Asia Paramitha.
CHARACTERIZATION OF MIXTURES OF NATURAL POLYMERIC MATERIALS FOR ENCAPSULATION, BY SPRAY DRYING
Authors: Caballero Pérez Luz Alba , Hernández Monzón Aldo , Tejedor Arias Rene , Montes Montes Everaldo Joaquin
Published: December 2023

Antecedentes: Las actuales tendencias están orientadas al uso de polímeros naturales como material encapsulante en la búsqueda de nuevas alternativas que mantengan la viabilidad de microorganismos a encapsular mediante el secado por aspersión. La caracterización de los materiales encapsulantes a emplear es muy importante para obtener resultados adecuados. Objetivos: El objetivo de esta investigación fue caracterizar una mezcla de polímeros naturales como material encapsulante de una mezcla de cultivos probióticos mediante uso de un equipo de secado por aspersión, marca© Vibrasec. Métodos: La parte experimental se realizó en las Instalaciones del Laboratorio de Ingenierías, Universidad de Córdoba, Montería Colombia. Se realizó la caracterización fisicoquímica del material encapsulante (almidón de yuca nativo, harina de avena y alginato de sodio): análisis granulométrico, temperatura vítrea, análisis a las suspensiones: pH, acidez, contenido de humedad, densidad aparente y viscosidad aparente, se evaluó la temperatura de gelatinización a diferentes concentraciones (3 ,5 y 7 %) y temperaturas (27, 60 y 90 °C) con el fin de determinar las temperaturas y concentraciones de sólidos adecuados del material encapsulante en mezcla para preparar las suspensiones que cumplan las restricciones del equipo de secado (700 mPas) © Vibrasec. Resultados: Los resultados indicaron que el alginato de sodio debe trabajarse máximo al 2 % de concentración de sólidos y una temperatura de 85 °C, mientras que la harina de avena (7 %) y el almidón de yuca nativo (10 %) deben trabajarse a una temperatura de 60 °C.  En la preparación de las disoluciones de las mezclas del material encapsulante se estableció que la máxima concentración de las mezclas debía ser del 12 % para obtener una buena homogenización de las mezclas y una viscosidad (700 mPas) dentro de la restricción de uso del equipo de secado © Vibrasec. Conclusiones: Se logró caracterizar el material encapsulante conformado por harina de avena, alginato de sodio y almidón de yuca nativo estableciendo las condiciones adecuadas para ser sometidos al secado por aspersión en el equipo Marca © Vibrasec.
GENERACIÓN DE DATOS SINTETICOS PARA EVALUAR LA ENFERMEDAD INFECCIOSA LEUCOSIS BOVINA
Authors: Ballesteros-Ricaurte Javier Antonio , González- Sanabria Juan Sebastián , Ordóñez Hugo
Published: December 2023

Los proyectos que se desarrollan en el sector de salud animal se enfrentan a limitaciones tecnológicas y científicas debido a la falta de información consistente y confiable, y a los altos costos que supone la recolección de información para los ganaderos. Así mismo, las limitaciones jurídicas en la divulgación de información por razones como las leyes de protección de datos conllevan atrasos en el desarrollo de políticas y estrategias, lo mismo que en la toma de decisiones. Ante esta falta de disponibilidad de información surge como solución la generación de datos sintéticos a partir de un conjunto de datos originales. Así, en este artículo se presenta un estudio a través del cual se valoraron tres métodos para generar datos sintéticos que reflejan el comportamiento de una enfermedad bovina en un conjunto de datos reales. El trabajo se basó en comparar algoritmos de aprendizaje automático, herramientas y métodos basados en modelos para mejorar el realismo de los datos sintéticos referidos al comportamiento de la enfermedad. El objetivo trazado fue encontrar el mejor modelo para la generación de datos sintéticos utilizando el caso de la enfermedad infecciosa mastitis bovina, ya que no se cuenta con suficientes datos sobre ella. Para validar los datos sintéticos fue necesario contrastar el conjunto de datos original y la información sintética, en busca de que el método seleccionado generara datos sintéticos con cualidades similares a las del conjunto de datos original.
ENERGÍA RENOVABLES Y MEDIDAS DE EFICIENCIA ENERGÉTICA APLICABLES A LAS INSTITUCIONES PRESTADORAS DE SALUD EN COLOMBIA
Authors: Hernández Palma Hugo , Novoa Dairo J. , Mendoza Cásseres Daniel
Published: December 2023

El contexto global actual ha incrementado la demanda y el uso de la energía eléctrica, ya que la mayoría de las herramientas o maquinarias que se utilizan en todos los sectores del mercado dependen de la electricidad. Por esta razón las energías renovables se han convertido en un elemento clave para garantizar la sostenibilidad. Las Instituciones Prestadoras de Servicio de Salud (IPS) requieren un alto consumo de energía por lo que incorporar fuentes de energía renovables es una oportunidad importante para diversificar la infraestructura energética. El objetivo es identificar los tipos de energía renovables incorporables en medidas de eficiencia energética en las IPS de Salud de Barranquilla.Método: La investigación fue de tipo descriptiva acompañada de una revisión documental. Las técnicas de recolección de datos utilizadas fueron la observación y matrices documentales.Resultados: Se considera la energía solar como una oportunidad para brindar beneficios económicos importantes a las IPS con la incorporación de un sistema mixto con módulos o celdas solares FV, cuyos costos resultan atractivos en comparación con las tarifas energéticas de compañías prestadora de servicio eléctrico y promover la cultura de ahorro energético.Conclusiones: La masificación del uso de las energías renovables para su uso en todos los sectores y actividades de la humanidad se presenta como urgente y las IPS son fundamentales para dicho cometido, tanto a nivel público como privado, debido a que estas deben potenciar el desarrollo y aplicación de estas desde la inversión planificada, garantizando una gestión eficiente de las mismas.
VISUALIZACIÓN GENERAL DE LAS CAPACIDADES DINÁMICAS: BASADO EN UN ANÁLISIS BIBLIOMÉTRICO
Authors: Garay Suárez Cindy Paola , Santamaría Escobar Álvaro , Martínez Benítez Jhon Pablo , D´luis Flórez Dani Daniel
Published: December 2023

Se analiza la producción científica relacionada con capacidades dinámica mediante el análisis bibliométrico realizado a partir de documentos recuperados de la base de datos SCOPUS correspondientes al período 2017- 2020, implementando una metodología cuantitativa de similitudes y representación de relaciones entre términos o palabras mediante mapas bibliométricos usando el software VOSviewer. La realización del estudio logró como resultado las visualizaciones de estructuras temáticas en las áreas de investigación de capacidades dinámica, permitiendo la identificación nueve (9) clusters que definen las principales corrientes de investigación. Los mapas revelan para el período analizado, una existencia de macrolínea de investigación robusta, que encierra trabajos sobre capacidad dinámica, adaptabilidad, integración, reconfiguración, estrategia, planeación estratégica, trabajo en equipo, transformación, capacidad de: absorción, adaptación, innovación; rendimiento financiero, desarrollo de nuevos productos, cultura organizacional, productividad, resiliencia, estrategia de flexibilidad, entre otros; sin embargo a nivel global, en especial en Latinoamérica, se muestra una incipiente investigación respecto a Capacidades Dinámicas específicas; en este caso las relacionadas con la gestión del talento humano. Asimismo, se identificó un eje de investigación consolidado en las ciencias de gestión. Se propone a futuro construir mapas bibliométricos, con otras bases de datos de forma comparativa que permitan analizar las capacidades dinámicas, sus elementos constituyentes y su evolución.
ARQUITECTURA PARA IMPLEMENTACIÓN DE SERVICIOS DE VIDEO SOBRE REDES MÓVILES MEDIANTE REDES DEFINIDAS POR SOFTWARE Y SEGMENTACIÓN DE RED
Authors: Chavez-Picon José Luis , Campo-Muñoz Wilmar Yesid , Chanchí-Golondrino Gabriel Elías
Published: December 2023

El presente artículo propone el diseño de una arquitectura para el despliegue de servicios de videostreaming sobre una infraestructura de redes móviles teniendo en cuenta los conceptos de redes definidas por software, radio definida por software y segmentación de red, con el objetivo de que sea flexible y escalable. Como principal contribución de este artículo, se presenta una arquitectura para el despliegue y consumo de servicios de videostreaming sobre infraestructura de red móvil basada en enfoques de redes definidas por software y segmentación de red. La arquitectura propuesta se especificó a través de la vista funcional y la vista de implementación, las cuales definieron los módulos funcionales extremo a extremo del servicio de videostreaming, así como las tecnologías utilizadas para la implementación de estas funcionalidades. El prototipo obtenido como instancia de la arquitectura propuesta permitió demostrar que puede ser considerado como un referente en diferentes entornos académicos y empresariales
DESARROLLO DE BLOQUES DE CONCRETO LIVIANOS UTILIZANDO RESIDUOS DE CONSTRUCCIÓN Y DEMOLICIÓN, Y CENIZAS DE TERMOELECTRICA
Authors: Molina Salazar David Leonardo , Lara Córdoba Angelica Lizbeth , Sánchez Molina Jorge
Published: December 2023

Los residuos de la construcción y demolición (RCD) representan un serio problema medioambiental global, debido a su elevado volumen e impacto en nuestro entorno. Este documento muestra la fabricación de bloques de concreto utilizando RCD, una opción tanto ecológica como económica que podría minimizar la cantidad de desechos que acaban en los vertederos y disminuir la explotación de nuevos materiales naturales. En Colombia, especialmente en el departamento del Norte de Santander, la gestión de RCD plantea importantes retos, aunque se están realizando esfuerzos para mejorar su manejo y fomentar una economía circular en el sector de la construcción. La meta de esta investigación fue incorporar RCD y ceniza de central termoeléctrica en la mezcla de agregados para la fabricación de bloques de concreto en el área metropolitana de Cúcuta, con el fin de fomentar la sostenibilidad en el sector constructor y minimizar el impacto medioambiental de los residuos procedentes de construcción y demolición. Se tiene la esperanza de que este estudio incentive el uso de RCD en la creación de bloques de concreto tanto en Colombia como en toda Latinoamérica.
CARACTERIZACIÓN MECÁNICA DE MICROCONCRETO FIBRO-REFORZADO CON FIBRAS DE GUADUA Y FIBRAS DE FIQUE
Authors: Palacios Pabón José Daniel , Capacho Carvajal María Alejandra , Sánchez-Molina Jorge
Published: December 2023

Las fibras son un material para reforzamiento de concreto que ha sido utilizado desde la antigüedad. El objetivo es desarrollar mezclas de microconcreto fibro-reforzados con fibras naturales. Se realizó un tratamiento químico con hidróxido de sodio para eliminar la lignina de las fibras disminuyendo la reacción alcalina entre el cemento y las fibras. Se realizaron dos mezclas de microconcreto: con fibras de guadua y fique. Para cada una de las mezclas se varió la cantidad de fibras entre 1 y 3% con el fin de determinar la proporción con mejores resultados. 12 réplicas se realizaron para cada una de las muestras. Se obtuvo que las fibras de fique con adición del 1% presenta resultados similares a microconcretos fibro-reforzado con fibras de vidrio. Mientras que las muestras reforzadas con fibras de guadua no presentan un comportamiento característico y por lo tanto no se puede identificar una adición de fibras óptima.
Features of Stress and Basic Beliefs of Parents of Children with Normative Development and with Disabilities
Authors:   Kostroma State University, Sevastyanova Ulyana Yu.
Published: December 2023

The article presents the results of the study of stress level of parents of children with typical development and with disabilities (mental retardation, autism spectrum disorders, cerebral palsy, visual and hearing impairment). The specificity of the expression of attitudes towards intensive parenting, basic personal and parental beliefs is analyzed. The study involved 190 respondents: 125 parents of children with normal development and 65 parents of children with disabilities. A high level of parental stress was identified among parents of children with disabilities. The data obtained allow us to say that there are such features of parental stress as an in-creased experience of loss of control over one’s life as a result of the birth of a child with disabilities, increased demands for development and upbringing, lack of pleasure, a reduction in the positive emotions that the ful-fillment of the parental role brings, a decrease satisfaction with oneself as a parent. Specific personal attitudes toward the experience of traumatic parenting have also been identified. Adults raising children with disabilities are dissatisfied with themselves, do not approve of their actions, and tend to consider themselves less success-ful than parents of children with normal development.
Regional System of Scientific and Methodological Support of Pedagogical and Managerial Personnel of Educational Institutions of General Education
Authors:   Moscow City University, Vachkova Svetlana N. , Gevorkyan Elena N. ,   Moscow City University, Salakhova Valentina B. ,   Moscow City University,   Centre for Security Studies of the Russian Academy of Sciences, Fedorovskaya Maria N. ,   Moscow City University
Published: December 2023

The effectiveness of the education system in general and general education in particular depends on highly qualified teaching staff carrying out educational activities. A high level of professional training of pedagogical staff implies their continuous professional development (training). In order to create an effective system of ad-vanced training for teachers and school leaders, it is necessary to have a comprehensive system of scientific and methodological support for this activity. Relevance of the problem under study. The relevance of the devel-opment of the system of support for the professional development of teaching staff is due to the lack of a uni-fied approach to the organization of the activities of methodological support services, as well as insufficient scientific methodological justification of this activity, the lack of connection between science and practice. Mate-rials and methods of research. Analysis of normative legal acts on the problem; official websites of federal and regional executive authorities managing in the field of education; analysis of domestic and foreign academic research on the problem. The results of the research and their discussion. The comparative analysis of the im-plementation of the system of scientific and methodological support of professional activity of teachers and school managers was carried out; the main directions of activity for the improvement and development of the system of scientific and methodological support of professional activity of teaching staff were determined; the system of professional development of teaching staff in educational organizations of general education was proposed.
Implementation of Health-Saving Technology in the Educational Process of Students of Higher Education
Authors:   Lipetsk State Pedagogical University named after P.P. Semenov-Tyan-Shansky, Kozub Marina V. , Ovchinnikova Aleksandra Zh. ,   Lipetsk State Pedagogical University named after P.P. Semenov-Tyan-Shansky
Published: December 2023

The article gives the author’s definition of health-saving technology; from the standpoint of the system-activity approach, its characteristics are given and the possibilities of implementation in the educational process of higher school are shown; the conceptual idea of implementing this technology in the process of working with students of higher education has been determined; the content of the targeted, content, practical and diagnostic components based on physical, mental and social health is revealed; motivational, cognitive, practical and re-flexive criteria are described, the levels of health-saving activity of higher school students are determined on the basis of these criteria and methods of M.V. Antropov, C. Spielberg, N.B. Stambulova, M. Rokich. The au-thor’s program of the elective course is proposed: “Organization of health-saving activities among students of higher education”. With the help of the criterion φ* – Fisher’s angular transformation, the effectiveness of the implementation of the developed health-saving technology was proved.
Alternative School Education: Approaches to Defining the Concept
Authors:   Moscow City Pedagogical University, Petryaeva Elena Yu.
Published: December 2023

The world community’s hopes for the formation of new institutional alternatives to existing school education are linked to alternative education. It is considered as a research field for exploring new ways of teaching children in a changing world. The aim of the article is to present approaches to the definition of the concept of alterna-tive education, to show its evolution from the late XX century to the modern stage. The main research methods are the analysis of scientific literature, in-depth interviews, and focus groups. It is emphasized that alternative education differs from public education by the style of interaction between the student and the teacher, the child and his environment. It assumes the subjectivity of the learner, individualization of the content of the educa-tional process, flexible training programs. Parents act as the main clients of education. Alternative educational projects lack a license. Unlike the late XX century, modern alternative practices are implemented not only by education specialists, but also by parents. It is legal and often features a synthesis of different methodologies, programs, and is supported by educational resources and digital tools, along with event-based educational formats. Alternative schools today are created not only by specialists in the field of education.
Social Well-Being of Buryatia Residents (Based on the Materials of a Sociological Study in 2023)
Authors:   Institute for Mongolian, Buddhist and Tibetan Studies of the Siberian Branch  of the Russian Academy of Sciences, Petrova Elena V. , Biltrikova Ayuna V. ,   Institute for Mongolian, Buddhist and Tibetan Studies of the Siberian Branch  of the Russian Academy of Sciences, Dashibalova Irina N. ,   Institute for Mongolian, Buddhist and Tibetan Studies of the Siberian Branch  of the Russian Academy of Sciences
Published: December 2023

The article deals with the social well-being of the residents of Buryatia in modern socio-political conditions. The content and conclusions are based on the results of a sociological study conducted in Buryatia in 2023. The article analyzes the indicators characterizing the social well-being of the respondents: the level of social opti-mism, social security, satisfaction with living conditions, the rating of the most serious problems that cause con-cern. It has been established that despite the difficult situation in general within the country and in the world, the existing problems, residents of the republic demonstrate optimism in assessing their future, without feeling much concern for the safety of themselves and their families. At the same time, in the ranking of the main re-gional problems and aspects of life that cause the least satisfaction, the leaders are such as increasing prices for food and essential goods; medical care, its quality, payment; increasing tariffs for housing and communal services; pollution environment, environmental problems; availability of money. It is concluded that it is neces-sary to implement measures to improve the level and quality of life in the region, which will contribute to main-taining a high level of social well-being and reducing the degree of migration attitudes of the population.
From the Experience of Organizing Pedagogical Support Adaptation of Students – Future Architects through Extracurricular Activities of the College
Authors:   Independent researcher, Igoshin Sergey N.
Published: December 2023

The article updates the importance of activities for pedagogical support of adaptation of college students in the context of growing interest among young people in secondary vocational education. The necessity of providing pedagogical support for the adaptation of students – future architects to the educational environment of the college, taking into account the specifics of their future specialty, is substantiated. It is proposed to use the pos-sibility of extracurricular activities as a means of ensuring the effectiveness of organizing pedagogical support for the adaptation of future architects. An analysis of the current state of knowledge of the problem in the scien-tific literature was carried out. On the basis of scientific positions determined based on the analysis of psycho-logical and pedagogical literature, a program of pedagogical support for the adaptation of first-year students of the specialty 02/07/01 was developed and tested at the State Educational Institution of Professional Education “Penza College of Architecture and Construction”. Architecture through extracurricular activities. The stage-by-stage organization and content of activities for pedagogical support of adaptation of future architects to the ed-ucational environment of the college through extracurricular activities in areas corresponding to the compo-nents of adaptation: educational-professional, socio-psychological and psychophysiological are characterized. The results of the program implementation are presented.