bluuebunny/crossref_metadata_2025 huggingface dataset:
EFFECT OF PREVIOUS SCORPION BITE ON THE EFFICACY OF INTRATHECALLY ADMINISTERED LEVOBUPIVACAINE IN SUBARACHNOID BLOCK
Authors: TRIPATHI SONALI , BADLANI BHARTI , JAIN AMIT KUMAR , MERAVI JYOTI
Published: February 2023

Objectives: Local anesthetics administered by spinal anesthesia acts through sodium channels. Mutations of sodium channels may be responsible for resistance to local anesthetic agents. The scorpion venom contains neurotoxins that block the sodium channels. In view of the high prevalence of scorpion stings in our region and observation of failure of spinal anesthesia in patients with a history of scorpion stings in routine practice, the present study is planned.
Methods: Forty patients of the American Society of Anesthesiologists Grade I or II who were undergoing infraumbilical surgery were divided into two groups as S (patients with h/o scorpion bite) and C (patients with no such history). The subarachnoid block was given with 3.2 ml of injection Levobupivacaine 0.5% heavy using 26 gauzes Quincke spinal needle. A blind observer recorded a sensory block using a needle prick and a motor block using the Bromage scale. Onset of sensory and motorized block, time to peak of sensory, and motor block and its relation to number of scorpion bites were observed in both the groups.
Results: The onset of sensory (2.61±1.68 mins) and motor blockade (2.91±1.80 mins) was significantly delayed in Group S (p=0.010 and 0.004, respectively). Time to peak of sensory and motor blockade was also prolonged in Group S (6.45±2.83 mins and 7.8±3.95 mins) compared to Group C (3.60±0.84 mins and 4.56±1.30 mins) which was statistically significant (p<0.05). Patients who had previous scorpion bites (Group S) had a significant failure rate of spinal anesthesia compared to the control group.
Conclusion: In this study, it was observed that the patients with scorpion bites had a significant failure rate of spinal anesthesia, suggesting probable resistance to the local anesthetic agents.
A PROSPECTIVE STUDY FOR THE EVALUATION OF NERVE CONDUCTION ABNORMALITIES IN NEWLY DIAGNOSED TYPE 2 DIABETIC PATIENTS
Authors: GOVINDARAJU LORD KRISHNA , VADIVEL KAMALAKANNAN , TALIKOTI PRASHANTH , T RAVI KUMAR , D JEYALAKSHMI , PRABHU V VENGADESH
Published: February 2023

Objectives: Peripheral neuropathy is the one of the frequently encountered complication of type 2 diabetes mellitus (T2DM). Although, the prevalence of diabetic peripheral neuropathy is associated with the diabetes duration, in some cases, the state of neuropathy is evident at the time of diagnosis. In this backdrop, the present study was carried out to evaluate the nerve conduction abnormalities in newly diagnosed T2DM.
Methods: This was a prospective study carried out on 30 newly diagnosed T2DM within a time range of 1 month. The patient symptoms such as weakness, burning and tingling senzation, hyperesthesia, and foot ulcer and gait abnormalities were recorded. Nerve conduction analysis of upper limb and lower limb of non-dominant hand side was done using neuro pack S1 machine.
Results: Thirty newly diagnosed T2DM patients were enrolled in the present study. The mean age of the patients was found to be 58.12±15.28 years. Distal motor latencies were elevated in T2DM patients as compared to the controls (p<0.05). Further, there was significant prolongation of F-wave latencies in the upper and Lower limbs of the patients as compared to the controls (p<0.05). In addition, there was a significant decrease in sensory conduction velocities in T2DM patients as that of the controls (p<0.05).
Conclusion: The study concludes that newly diagnosed T2DM is susceptible to DPN with high incidence rates. Hence, it is essential to perform the nerve conduction studies in newly diagnosed T2DM patients for the early detection and better management and also to prevent the complications.
Herramientas digitales para estudiar la cultura náhuatl
Authors:   Miembro honorario del Centro Nacional de la Investigación Científica de Francia a través del Centro de Estudios de Lenguas Indígenas de América, Thouvenot Marc , Acevedo Frómeta Ónix ,   Instituto de Investigaciones Históricas
Published: February 2023

Este libro presenta un conjunto de herramientas digitales para que quienes se interesan en la cultura náhuatl tengan a la mano recursos documentales y metodologías útiles que sirvan para solventar problemas de diversa índole en su proceso de investigación. A lo largo del texto se le sigue la pista al chalchihuitl, “jade”, y se utilizan estas herramientas para interrogar a las fuentes, tanto las alfabéticas como las pictográficas, y de este modo sacar a la luz sus significados. Se crea así un gran campo semántico desde donde se construyen y articulan los sentidos de la palabra. El contenido interactivo ofrece cientos de enlaces a sitios de interés o bases de datos con fuentes primarias o estudios que ayudarán a localizar estos materiales con gran facilidad. También se incluye más de una decena de tutoriales que favorecen la comprensión de algunas de las herramientas.
The Effects of Job Stress on Burnout among Military Officers: The Mediated Moderation Effect of Emotional Intelligence through Cognitive Emotion Regulation Strategies
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kim Haesung , Lee Jaeeun
Published: February 2023

Objectives This study aimed to investigate the mediated moderation effect to confirm whether emotional intelligence moderates the effect of job stress on burnout among military officers by mediating effect of cognitive emotion regulation strategies.
Methods The Job Stress Scale, Exhaustion Scale, Cognitive Emotional Control Strategy Scale, and Emotional Intelligence Scale were all surveyed in this study. The data collected from 359 military executives was analyzed. SPSS/WIN 25.0 was used for basic statistical processing such as descriptive statistics and correlation analysis. And the statistical results of Hayes' (2018) model 15 analysis using SPSS PROCESS MACRO V3.4 were examined using a step-by-step approach suggested by Muller et al. (2005) to verify the mediated moderating effect.
Results In the relationship between job stress and burnout, the mediated moderating effect of emotional intelligence through the cognitive emotion regulation strategy was found to be significant. The moderating effect of emotional intelligence, in particular, was significant in the positive relationship between job stress and burnout. This moderating effect was confirmed through the mediation of cognitive emotion regulation strategies.
Conclusions These findings explain why there is a relatively weak link between job stress and burnout in the group with high emotional intelligence because cognitive emotion regulation mechanisms are employed. In other words, the employment of positive emotion management techniques lessens the impact of work stress under circumstances of high emotional intelligence. Burnout results from not using the proper emotion regulation mechanisms for job stress in low emotional intelligence environments. This implies that improving emotional intelligence through the use of adaptive cognitive emotion regulation mechanisms is required to lessen burnout among military officers brought on by job stress.
A Consensual Qualitative Research on Learning Experience of Special Graduate School Students
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lim Yooha , Kim Jinsun , Chung Yoonkyung
Published: February 2023

Objectives The aim of the study is to analyze the learning experience of adult learners in professional counseling program based on the expectancy-value theory.
Methods Focus group interviews were conducted with ten students in the program and the data was analyzed using Consensual Qualitative Research(CQR) method. Consensual Qualitative Research is a method in which a research team consisting of evaluators and one supervisor analyzes data and checks the overall pattern through consensus.
Results The major results are as follows. First, most of the students had a motivation to go to graduate school by recognizing the intrinsic value such as interest in counseling, the desire to learn, and the utility value such as the second job preparation and center opening plan. However, there was no expectancy belief for success that the degree course would be completed successfully. Second, the anticipated cost before entering the program is the opportunity cost incurred by not being able to participate in work or family life as before and the effort cost from engaging in the program. Despite of the cost perception, they decided to participate in the program. After entering the program, these anticipated cost perceptions partly continued with other newly emerged costs, such as doubts and concerns about ability in counseling and counseling research methodology. Third, emotional support from the interpersonal relationships, interest and mastery experience in the counseling domain were the most influential sources for being continuously engaged in the program, compared to the perceptions of utility values such as obtaining a license or preparing for a second job were dominant before entering the program.
Conclusions This research allowed exploration of adult learner's various difficulties and sources of continuing study during attending a special graduate school majoring in counseling. Implications for further research and practices were provided.
A multi-case study on the development and implementation of convergence curriculum for pre-service teachers: Focusing on the three instructors’ experiences
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Choi Seyoung , Yoon Chaeyoung , Cho Hyunhee
Published: February 2023

Objectives The purpose of this study is to examine the development, implementation, and evaluation process of convergence curricular for pre-service teachers, and to analyze the instructors’ internal and external factors that influenced their practice of the curricula along with the related difficulties.
Methods In this study, three cases of developing and implementing convergence curriculum for pre-service teachers were explored. First, individual interviews were conducted with the instructor in charge of each case, and various literature data were collected for a comprehensive understanding and explanation of each case. The collected data were analyzed in inductive methods and procedures focusing on the development-implementation- evaluation process and related factors of the convergence curriculum for pre-service teachers.
Results The convergence curricula for pre-service teachers were practiced in various ways in the form of interdisciplinary content integration(webbed, integrated, shared), learner needs survey, evaluation method(criteria- based evaluation, relative evaluation, alleviated relative evaluation), collaboration between instructors, connection with various sites including school sites, and evaluation-and-feedback. Next, the instructors' perceptions of teacher education and convergence education, the form of subjects(liberal arts, major subjects), and human and material support emerged as factors influencing the practice of the convergence curriculum. Finally, communication and collaboration between instructors were identified as one of the biggest difficulties in the practice of convergence curriculum for pre-service teachers, which was closely related to the fragmented culture and system in the current teacher preparation programs.
Conclusions For further development and implementation of convergence curriculum for pre-service teachers, first, in the development stage of the convergence curriculum, teacher educators need to select academic (curricular) integration models, and actively reflect the learner's needs in designing their instruction contents and methods. Second, it is necessary to expand the criteria-based evaluation system to facilitate the practice of the convergence curriculum (i.e., increasing the preference of pre-service teachers for convergence education subjects and the flexibility of teaching and learning). Third, in order to invigorate the convergence curriculum for pre-service teachers, it is necessary to promote cooperation between instructors from various academic backgrounds, expand opportunities to apply what they learned to the context of school and classroom, and provide opportunities to get involved in diverse field experiences.
An Action Research Study on Applying Mobile-App-Based English Activities to Develop 26 4th Graders’ Interest in English Learning
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Oh Maria , Chae Songhwa
Published: February 2023

Objectives In this study, for the purpose of improving 26 4th graders’ English learning interest, a homeroom teacher conducted an action research study and helped their mobile-app-based English learning and her adviser supervised the teacher to conduct the research study successfully, according to qualitative research tradition. Although many theorists and scholars propose promising effects of mobile-app-based English learning there is not much mobile-app-based English learning research conducted with primary school students and teachers at public primary school settings. This is an action research study to fill the gap in the previous studies.
Methods During the spring semester of 2022, 26 elementary school students in a southern province performed mobile-app-based English learning activities with their homeroom teacher in a 30-minute morning-class session and in a 40-minute club activity session. Teacher observation reports, survey results and interview data are collected before, in or after the mobile-app-based English teaching/learning class.
Results The first result is that almost all of the 26 students liked the English learning activity of singing English songs using YouTube app. As for the second result, among the four English learning apps applied in the study, most of the students liked the Dino Buddies series of the Little Fox app and the Kahoot word quiz app the most, and low-English-learning-autonomy students liked the ‘FunEasyLearn’ English app the most. The third result is that all 26 students' interest in learning English improved while participating in the study, with varying degrees of improvement. The fourth result is that the preference for mobile-app-based English learning activities varies greatly by student according to the level of English-learning interest improvement.
Conclusions The results of the study showed that 26 students who conducted English learning using mobile apps for one semester developed interests in learning English and that they all had various preferences for mobile-app-based English learning activities. Based on the study results, it can be predicted that the learning effect will be maximized if mobile-app-based English teaching is carefully planned and implemented according to the characteristics, autonomy, personality, and English proficiency levle of each student as a learner. In particular, when carrying out mobile-app-based English teaching for students with low autonomy, it would be very helpful if an individual learning helper or an assistant teacher helps their learning. It seems that further research is still needed to know how to implement mobile-app-based primary English education for Korean learners.
An Analysis of Factors on Low Academic Achievement in Mathematics in Middle School Years
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lim Hyejung , Choi Yunjin
Published: February 2023

Objectives The purpose of this study is to identify the factors affecting the low mathematical achievement of middle school students and to derive effective implications for the basic academic achievement guarantee policy.
Methods This study used the 4th to 6th data of the 4th-grade panel of the Gyeonggi Education Longitudinal Study (GEPS). For 5,376 middle school students, we specified a hybrid model that combines both fixed and random effect. The low achievement level represents the lowest 20% in the group. Since this is a binary variable, the panel logit model was applied. Based on previous research, personal characteristics, family background, and school context factors were put as independent variables.
Results Among the intra-individual effects, the changes in academic amotivation and math class attitude showed significant influence on the possibility of low achievement in math. Among the inter-individual effects, variables such as expected level of education, the degree of smart devices usage for learning and non-learning, family income level and parents' educational background, private tutoring in mathematics, attitude in mathematics class had a significant effect on the possibility of low performance in mathematics. In addition, discriminatory atmosphere based on school achievement, participation in after-school classes, and location of school are identified as significant influencing factors.
Conclusions Focusing on the variables that had a significant influence on the possibility of low achievement in mathematics, suggestions were made on the effective educational intervention, and on the policy such as the 『Comprehensive Plan for Guaranteeing Basic Academic Achievement』.
Mind Wandering of Elementary School Pre-service Teachers according to the Video Type during Earth Science Video Lecture
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Minha , Kim Seongun , Yang Ilho
Published: February 2023

Objectives This study examines the attention of elementary school pre-service teachers according to the two types of lectures, Picture-In-Picture (PIP) and Lecture Capture (LC), while watching science video lecture s using a eye-tracking device. Mind Wandering (MW) was collected and analyzed for this purpose.
Methods The participants were 18 pre-service teachers (12 women, 6 men), and the task was a video lecture for a university earth science education lecture, and the theme was a lecture on how to guide the rotation of the earth, orbit, and phase change of the moon to elementary school students. Data were collected with the Tobii Pro Spectrum eye- tracking device, and when sections with a fixed duration of 400 ms or more lasted for more than 2 seconds were determined as the MW section. The MW was analyzed according to two image types. Attention and MW inducing factors were identified through interviews and screen analysis.
Results As a result, it was found that the LC type had a shorter MW Duration due to a significant difference than the PIP type. This suggests that the LC type is more effective in maintaining the learner's attention than the PIP type. The gaze plot during MW shows a phenomenon in which gaze movement is fixed to one place, and in the LC type, gaze fixing to the instructor was remarkable. During video lectures, factors such as repeated explanations, static screens, difficulty of learning tasks, and task familiarity were identified as factors that could cause MW. In addition, pre-service teachers preferred the LC type to the PIP type.
Conclusions Developing video lectures in LC type will help maintain attention, and the design of video lectures should avoid repeated explanations, static screens, high-level cognitive load presentations, and learning tasks that can cause students to get tired of, and should be developed to continuously provide visual or auditory stimuli.
Aspects of song making in 5-year-old children's free play
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Bo-Ram , Baek Jee-Hea
Published: February 2023

Objectives This study observed the musical expression and musical play of 5-year-old children in free play, and examined the genre of songs and the aspects of song-making in the process.
Methods The researcher was participatory observation 16 5-year-old children from A daycare center located in D city for about 6 months from March to August 2021. Data were collected through video recording and recording of the process of making songs spontaneously appearing in children's free play, and data such as teacher's observation diary and researcher's diary were additionally collected and analyzed.
Results First, song-making in the free play of 5-year-olds started with various genres of music, and appeared as trot singing, changing the words of a song while singing a cartoon theme, and making a new song with a nursery rhyme. Second, the aspects of children's voluntary song-making were expressed by expressing rhythm, playing scales with melodic instruments, and changing the words of the song, and they made Bora class battle cry, our class songs, and welcome songs.
Conclusions This suggests that educational support for the provision and utilization of various music genres is necessary for young children's creative music-making experience, and music utilizing musical elements such as rhythm, melody, tone, and form to develop musical expression and cognitive ability. It suggests that there is a need to actively provide activities. In addition, it suggests that teachers should be sensitive to children's active musical expressions and reactions, focus on children's creativity in musical activities, and pay attention to new music created by children.
Nutrient intake by body image distortion in Korean adolescents: Based on the 6th and 7th Korea National Health and Nutrition Examination Survey
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Jinhyun , Kye Seunghee
Published: February 2023

Objectives This study was conducted to examine why Korean adolescents have a distorted body image and assess the nutrient intake according to their body image recognition status.
Methods Data of 2,337 adolescents aged 12-18 years who participated in the 6th and 7th Korea National Health and Nutrition Examination Survey conducted from 2013 to 2017 were analyzed. The body image distortion status of the participants was determined using the body mass index (BMI) and body image responses as objective and subjective indicators, respectively. The participants were divided into groups based on their body image recognition status: under-distorted group, normal group, and over-distorted group. The energy intake, three major nutrient intake and, nutrient intake to the dietary reference intake ratio, and proportion of patients with intakes below the dietary reference intake were calculated for each body image recognition group.
Results Among the male adolescents, 24.3% were included in the under-distorted group and 9.2% in the over-estimated group, thus showing that the proportion of adolescents in the under-distorted group was higher. Among the female adolescents, 13.2% were included in the under-distorted group and 15.6% in the over-distorted group, thus showing that the proportion of adolescents in the over-distorted group was higher. The proportion of male adolescents who consumed less than the estimated average requirement (EAR) of riboflavin and that of female adolescents who consumed less than the EAR of protein and thiamine were significantly higher in the over-distorted group than those in the under-distorted group and the normal group, respectively. The NAR of vitamin A, vitamin C, and calcium were low (0.44-0.62) in all three body image recognition groups regardless of sex.
Conclusions Thus, continuous education on healthy, well-balanced eating habits and body image is necessary for Korean adolescents to develop healthy mental and physical body image.
Система образования в Египте во время правления хедива Исмаила (1863–1879)
Authors: Moskalets O. V.
Published: February 2023

The article discusses the period of the reign of Khedive Isma‘il from the standpoint of his influence on the formation of the education system in Egypt. The author gives a brief overview of Khedive’s socio-economic reforms, especially noting his achievements in the field of education. This article analyzes the “Law of Rajab 10th” (1868), the main purpose of which was to promote public education and establish a new type of school under the auspices of the state. The law developed plans for the construction of modern schools of a new type in each city, prepared projects for the reorganization of Koranic schools (kuttabs) and set the task of expanding the state education system. In addition, textbooks were unified and were now published after the approval of the Ministry of Education. The author elaborates on the structure of the education system formed during this period, noting the cultural continuity and historical educational traditions that had not been sacrificed to new knowledge, but were joined in a single model, representing the convergence of religious and secular education. The article points out that during the reign of Khedive Isma‘il the first public schools for girls were opened, and since that female education has become popular among the upper classes of Egyptian society. At the same time, with the support and encouragement of the Khedive, there was a growth of schools of foreign communities. Ultimately, the author comes to the conclusion that despite the financial difficulties that prevented the implementation of all planned educational reforms, this reform proved to be the most useful and necessary at that time. During this period, a clear and orderly system of education management was created, and a plan for a unified state education that should work for the benefit of society was developed.
Konsep Belajar Syaikh Az-Zarnuji dan Relevansinya terhadap Pendidikan Modern
Authors: Abdullah Zakie
Published: February 2023

This article focuses on Shaykh Az Zarnuji's book Ta'lim al-Muta'allim. Shaykh Az Zarmuji explained that learning is an obligation that has been prescribed by religion both through the Al-Quran and Hadith, and all of this is done through a teaching process that is both divine and basyariyah in nature. This study shows that there are two learning methods of Shaykh Az Zarnuji, namely, the ethical method in the form of intention to learn and the strategic method, which includes how to choose lessons, choose teachers, choose friends, and take study steps. In general, the book of Ta'lim Muta'allim is still very relevant to be applied in the contemporary world of education, especially in terms of aqidah and morals, as well as mutual respect between students and educators for the knowledge gained in the teaching and learning process carried out in an educational institution.AbstrakKajian ini berusaha memfokuskan pada tulisannya Syaikh Az Zarnuji yang berjudul Ta’lim Al Muta’allim. Syaikh Az Zarmuji menjelaskan bahwa belajar merupakan sebuah kewajiban yang telah di syariatkan oleh agama baik melalui Al-Quran maupun Hadist, dan semua ini melalui proses pengajaran yang bersifat Ilahiyah maupun Basyariyah. Kajian ini menunjukkan bahwa terdapat dua metode belajar Syaikh Az Zarnuji yaitu metode bersifat etik yang berupa niat dalam belajar dan metode bersifat strategi yang mencakup cara memilih pelajaran, memilih guru, memilih teman, dan langkah langkah belajar. Secara umun kitab Ta’lim Muta’allim masih sangat relevan untuk diterapkan di dalam dunia pendidikan kekinian, terutama pada sisi aqidah dan akhlak serta saling menghargai antara peserta didik dengan tenaga pendidik atau peserta didik terhadap ilmu yang didapatkan dalam proses belajar mengajar yang di laksanakan pada suatu lembaga pendidikan.
Efek Ekstrak Etanol Daun Kelor terhadap Kadar Kreatinin Serum dan Superoksida Dismutase Tikus Model 5/6 Subtotal Nefrektomi
Authors: Kuncorojati Raden Alif , Afifaningrum Haniy Thri , Swastika Anis , Afifah Afifah
Published: February 2023

Chronic Kidney Disease (CKD) is still a major problem in the health sector in the world, including in Indonesia. One of the main pathomechanisms in CKD is oxidative stress. Superoxide dismutase (SOD) is an enzyme that plays a role in fighting oxidative stress. Oxidative stress can be overcome with antioxidants both from inside the body and from the outside obtained from natural materials. Moringa leaves (Moringa oleifera L.) have the potential to prevent the progressivity of CKD because of their flavonoid content which has an antioxidant effect. This study aimed to analyze the effect of Moringa leaf ethanol extract (MLEE) on serum creatinine and SOD levels in rat model 5/6 subtotal nephrectomy. This research is an experimental study with a post-test only with a control group design. A total of 30 male white rats were randomly divided into 5 groups. Group A: sham control, B: subtotal nephrectomy, C, D, and E: treatment groups with MLEE of 200, 400, and 800 mg/kg BW, respectively. On the 15th day after the administration of extracts or aqua dest, sham surgery was carried out in group A, and 5/6 of subtotal nephrectomy in groups B, C, D, and E continued to administer extracts and aqua dest until the 21st day. A blood sample is taken on the 22nd day after surgery, checked serum creatinine levels and SOD. Data were analyzed using One-way ANOVA. The results showed that there was a significant difference in the average serum creatinine levels (p
The stimulus of factors in implementing the e-governance concept in the emerging economy
Authors: Mutasa Laizah Sashah , Iyamu Tiko
Published: February 2023

This paper reports on a case study where the Namibian environment is used, to gain a deeper understanding of the factors that influence e-governance and how those factors manifest themselves. This study is motivated by the continuous challenges that are encountered by many African countries, either in the development or implementation or both, of the e-governance solution. The interpretive approach was employed, and qualitative data were gathered using the semi-structured interview technique. Activity theory was used as a lens to guide the analysis of the data, from which six factors were found to influence the implementation of e-governance in the country. The factors are 1) know-how; 2) requirements of both technical and non-technical components; 3) political will, which draws on power to make decisions; 4) heterogeneity; a repertoire of actors; 5) power relationship and 6) governance, which includes standards, policies, and principles. The empiricism nature of the study enhances the implementation of the e-governance solution, which can result in improved service delivery in the country.
Incidence, hospitalization, and mortality in children aged five years and younger with respiratory syncytial virus-related diseases: A systematic review and meta-analysis
Authors: Duan Yuping , Jiang Mingyue , Huang Qiangru , Jia Mengmeng , Yang Weizhong , Feng Luzhao
Published: February 2023

Objectives: Respiratory syncytial virus (RSV) is a leading cause of
lower respiratory tract infection in young children. We aimed to analyze
the factors affecting the estimation of RSV-related disease burden, and
furthermore, to provide evidence to help establish a surveillance
system. Methods: We searched for literature published in English or
Chinese between 1 January, 2010 and 2 June, 2022. The quality of the
included articles was assessed using the Agency for Healthcare Research
and Quality scale. Random-effects models were used for data synthesis
and subgroup analyses. This review was registered in the Prospective
Register of Systematic Reviews (PROSPERO: CRD42022372972). Results: We
included 44 studies (149,321,171 participants), all of which were of
medium or high quality. The pooled RSV-associated disease incidence,
hospitalization rate, in-hospital mortality, and overall mortality rates
in children aged 5 years and younger were 9.0% (95% confidence
interval [CI]: 7.0–11.0%), 1.68% (95% CI: 1.30–2.05%), 0.45%
(95% CI: 0.38–0.52%), and 0.05% (95% CI: 0.04–0.06%),
respectively. Age, economics, surveillance types, case definition, and
data source were all influencing factors. Conclusions: A standardized
and unified RSV surveillance system is required. Case definition and
surveillance types should be fully considered for surveillance of
different age groups.
Dual-slit confocal light-sheet microscopy using birefringent crystals
Authors: Xu Xin , Ye Hone , Wang Jixiang , Zhang Xin , Shi Guohua
Published: February 2023

We present a method to use a birefringent crystal for generating two
illumination beams in a digital scanned laser light-sheet microscopy
(DSLM) system. Upon this, a conventional confocal DSLM can be easily
upgraded to a dual-slit confocal DSLM with two-fold imaging speed. We
have implemented this method to our bidirectional DSLM system, locating
two identical calcite crystals on both illumination paths from both
sides of the sample. The neurons of in vivo larval zebrafish have
been fast imaged with sterling image quality, especially
~2.5 times higher contrast, compared to the conventional
DSLM.
A Novel PFM/PWM Hybrid Modulated Single-stage FSBB-LLC AC-DC Converter
Authors: Yi Junhong , Ma Hongbo , Lu Song , Li Xiaobin , Chen Zhe
Published: February 2023

By integrating the Four Switch Buck-Boost (FSBB) PFC and full-bridge LLC
resonant converter, a novel single-stage FSBB-LLC AC-DC converter is
proposed. Moreover, a dual-loop feedback control strategy based on
PFM/PWM hybrid modulation is proposed for obtaining the desired bus
voltage and stable output voltage. The bus voltage feedback loop is
utilized to regulate the bus voltage by selecting the boost or
buck-boost mode; the output voltage feedback loop is employed to
stabilize the output voltage by adjusting the switching frequency or
phase shifting angle. Furthermore, an optimal parameter design based on
power balance principle is also derived. The experimental results of an
85~300V input, 12V/25A output prototype demonstrate
that: (1) low and narrow bus voltage of 240~340V is
achieved under the entire input and output condition; (2) the LLC cell
operates as a DCX converter over the whole load range as the input
voltage exceeds 120V; (3) the output voltage is well regulated even
under the no-load condition; (4) ZVS feature for the shared main
switches is still maintained; (5) a peak efficiency of 90.9% and PF
values above 0.987 are achieved.
Hyper IgE Syndrome Related Disease Treated with Dupilumab: A Case Report
Authors: Kao Andrew , Deirawan Hany , Poowuttikul Pavadee , Daveluy Steven
Published: February 2023

We describe a case of a 2-month-old female displaying clinical phenotype
of HIES related disease with severe eczematous dermatitis recalcitrant
to corticosteroids. Genetic panel showed a variant of unknown
significance in key immune regulator of PGM3. Patient achieved nearly
complete response from off-label use of dupilumab.
No Substitute for Hard Work: Dedication to the Diabetes Community
Authors: Kirksey Otis
Published: February 2023

Editor’s Note

This article is adapted from a speech Dr. Kirksey delivered in June 2022 as President, Health Care & Education of the American Diabetes Association. He delivered his address at the Association’s 82nd Scientific Sessions in New Orleans, LA. A webcast of this speech is available for viewing on the DiabetesPro website (https://professional.diabetes.org/webcast/president-health-care-education-address-and-outstanding-educator-diabetes-award-lecture).
Safety and Efficacy of the Omnipod® 5 Automated Insulin Delivery System in Adults with Type 2 Diabetes: From Injections to Hybrid Closed-Loop Therapy
Authors: Davis Georgia M , Peters Anne L. , Bode Bruce W. , Carlson Anders L. , Dumais Bonnie , Vienneau Todd E. , Huyett Lauren M. , Ly Trang T.
Published: February 2023

  

Objective: Automated insulin delivery (AID) has rarely been studied in adults with type 2 diabetes. We tested the feasibility of using AID for type 2 diabetes with the Omnipod 5 System in a multicenter outpatient trial. 

Research Design and Methods: Participants were previously on either basal-only or basal-bolus insulin injections, with or without the use of continuous glucose monitoring (CGM), and had a baseline HbA1c ≥8% (≥64mmol/mol). Participants completed 2 weeks of CGM sensor data collection (blinded for those not previously using CGM) with their standard therapy (ST), then transitioned to 8 weeks of AID. Prior basal-only participants used the AID system in Manual Mode for 2 weeks prior to starting AID. Anti-hyperglycemic agents were continued at clinician discretion. Primary safety outcomes were percent time with sensor glucose ≥250mg/dL and <54mg/dL during AID. Additional outcomes included HbA1c and time in target range [70-180mg/dL (TIR)]. 

Results: Participants (N=24) had a mean (±SD) age of 61±8 years with baseline HbA1c 9.4±0.9% (79±10mmol/mol), and diabetes duration of 19±9 years. Percent time ≥250mg/dL decreased with AID by 16.9±16.2% (p<0.0001) while percent time <54mg/dL remained low during both ST and AID (median [interquartile range] 0.0% [0.00%, 0.06%] vs. 0.00% [0.00%, 0.03%], p=0.4543). HbA1c decreased by 1.3±0.7% (14±8mmol/mol, p<0.0001) and TIR increased by 21.9±15.2% (p<0.0001) without a significant change in total daily insulin or body mass index with AID.

Conclusions: Findings from this feasibility trial of AID in adults with type 2 diabetes with sub-optimal glycemic outcomes justify further evaluation of this technology in this population. 
Glomerular hyperfiltration predicts kidney function decline and mortality in type 1 and type 2 diabetes: a 21-year longitudinal study
Authors: Moriconi Diego , Sacchetta Luca , Chiriacò Martina , Nesti Lorenzo , Forotti Giovanna , Natali Andrea , Solini Anna , Trico Domenico
Published: February 2023

  

Objective. To evaluate the prognostic value of glomerular hyperfiltration on long-term kidney-related outcomes and mortality in subjects with diabetes.

Methods. We retrospectively analyzed 21-year longitudinal data from 314 patients with long-standing type 2 or type 1 diabetes. Glomerular hyperfiltration was identified based on the age- and sex-specific distribution of the glomerular filtration rate measured by 99mTc-DTPA dynamic renal scintigraphy (mGFR). The primary outcome was a composite of doubling of serum creatinine, end-stage kidney disease (ESKD), or cardiorenal death. The kidney-specific outcome was a composite of doubling of serum creatinine, ESKD, or renal death.

Results. Over a median of 21.0 years, the primary composite outcome occurred in 25 (39.7%), 24 (38.1%), and 46 (24.5%) participants with high (H-mGFR, n=63), low (L-mGFR, n=63), or normal glomerular filtration (N-mGFR, n=188), respectively. Compared with N-mGFR, the hazard ratio [95% confidence interval] for the primary composite outcome was 2.09 [1.25–3.49] in H-mGFR and 1.81 [1.05–3.16] in L-mGFR. The hazard ratio for the kidney-specific composite outcome was 4.95 [2.21–11.09] in H-mGFR and 3.81 [1.70–8.56] in L-mGFR. The hazard ratios for doubling of serum creatinine and cardiorenal death were 4.86 [2.18–10.90] and 2.18 [1.24–3.83] in H-mGFR, respectively, and 4.04 [1.77–9.20] and 2.26 [1.27–4.01] in L-mGFR. 

Conclusions. Glomerular hyperfiltration, similar to hypofiltration, increases the combined risk of worsening kidney function and mortality from cardiovascular or renal causes in patients with diabetes. These findings encourage the active screening of these patients to optimize risk stratification and treatment of subclinical kidney disease.  
Effects of Intensive Systolic Blood Pressure Lowering on End-Stage Kidney Disease and Kidney Function Decline in Adults with Type 2 Diabetes Mellitus and Cardiovascular Risk Factors: A Post-hoc Analysis of ACCORD-BP and SPRINT
Authors: Tawfik Yahya M.K. , W. Van Tassell Benjamin , Dixon Dave L , Baker William L. , Fanikos John
Published: February 2023

  

Objective: To determine the effects of intensive systolic blood pressure (SBP) lowering on the risk of major adverse kidney outcomes in people with type 2 diabetes mellitus (T2DM) and/or prediabetes and cardiovascular risk factors. 

Research Design and Methods: This post-hoc ACCORD-BP subgroup analysis included participants in the standard glucose-lowering arm with cardiovascular risk factors required for SPRINT eligibility. Cox proportional hazards regression models compared the hazard for the composite of dialysis, kidney transplant, sustained eGFR <15 ml/min/1·73 m2, serum creatinine >3·3 mg/dL, or a sustained eGFR decline ≥57%, between the intensive (<120 mm Hg) and standard (<140 mm Hg) SBP lowering arms.

Results: The study cohort included 1,966 SPRINT-eligible ACCORD-BP participants (40% women) with a mean age of 63 years. The mean SBP achieved after randomization was 120 ± 14 mm Hg and 134 ± 15 mm Hg in the intensive and standard arms, respectively. The kidney composite outcome occurred at a rate of 9.5 events and 7·2 events per 1,000 person-years in the intensive and standard BP arms (HR [95% CI]: 1·35 [0·85-2.14]; P = 0·20). Intensive SBP lowering did not have an effect on the risk of moderately (HR [95% CI]: 0·96 [0·76-1·20]) or severely (HR [95% CI]: 0·92 [0·66-1·28]) increased albuminuria. Including SPRINT participants with prediabetes in the cohort did not change the overall results.

Conclusion: This post-hoc subgroup analysis suggests that intensive SBP lowering does not increase the risk of major adverse kidney events in individuals with T2DM and cardiovascular risk factors.
La gran renuncia, aspectos psicológicos, económicos, y la resiliencia organizacional en EUA y México
Authors: Guerrero-Sánchez Pablo , Guerrero-Grajeda José
Published: February 2023

El presente trabajo se ubica dentro de los estudios organizacionales, económico-administrativos; busca explicar el fenómeno de la gran renuncia y su comportamiento complejo en la sociedad actual. El objetivo es analizar las percepciones de los trabajadores mediante una metodología cualitativa, así como de los empleadores en algunas organizaciones de Estados Unidos y de México de distintos tamaños por medio de gráficas estadísticas y fórmulas matemáticas que explican la relación entre el comportamiento organizacional y social estructural. En las conclusiones resalta que la percepción entre trabajadores y empleadores es diferente, por lo tanto, las estrategias implementadas por los empleadores para lograr la resiliencia no corresponden con lo percibido por los empleados.
Information system project for startup of supporting internet tourism in Ukrainian territory
Authors:   Lviv Polytechnic National University, Borovets Nazar , Rishnyak Ihor ,   Lviv Polytechnic National University, Chyrun Lyubomyr ,   van Franko National University of Lviv
Published: February 2023

oday, the issue of tourism, travel, research of the city or its history remains quite relevant. Awareness of one’s identity, learning the history of one’s people are important aspects of life, or learning the culture of other peoples. Although the Covid-19 pandemic and the war have put this issue on the back burner, it adds new challenges to it. On the one hand, interest in research and learning something new is enhanced by isolation, both internal - limiting people’s personal contacts, and external – closed borders and a limited flow of tourists. On the other hand, it creates new requirements for providing and using tourism as a product. But these are only additional time factors. The essence of tourism, travel and research is not going anywhere. The goal of the project: to create a new information system that will help in the formation of the tourism product of small towns.
Speech intelligibility of English spoken by Indonesian and Taiwanese speakers and judged by Taiwanese listeners: application of TOCS+ automatic software
Authors: Windiahsari Windiahsari , Chen Li-Mei
Published: February 2023

Former investigations were about the familiarity advantage that people with the same language backgrounds are more intelligible. Besides, particular English was most intelligible to participants with high certain English familiarity. This study investigated how Taiwanese listeners judge the English speech intelligibility of Taiwanese and Indonesian speakers. Thirty Indonesian speakers and thirty Taiwanese speakers participated in this study. Ninety Taiwanese listeners were recruited to judge speech intelligibility. The recording and judging process used the TOCS+ software (Hodge et al., 2009). The software provided 124 contrast items of minimal pairs for the recognition task, including contrast of syllable shape, vowels, and consonants. The listeners' judgments were then analyzed by the TOCS+ software automatically. It was found that Taiwanese English speaker is more intelligible to Taiwanese listeners. The variables that predict intelligibility for Indonesian speakers are syllable shape contrast item correct (SSIC) and consonant item correct (CIC), while Taiwanese speakersâ€™ SSIC and vowel item correct (VIC) did not predict intelligibility. Only CIC predicts intelligibility. Both groups made similar errors in consonant voicing. The study's findings contribute to the teaching materials for the English preparation of students who will study abroad.Â Â Â
PENGARUH TRUNK BALANCE EXERCISE DALAM MENINGKATKAN KESEIMBANGAN KINERJA OTOT ERECTOR SPINE PADA PENGHOBI FUTSAL
Authors: Nasirudin Yusuf , Yudistira Efraldo , Khasanah Al Um Aniswatun
Published: February 2023

Di dalam permainan futsal, keseimbangan kinerja otot postural dibutuhkan untuk menjaga kestabilan tubuh untuk menerima operan dan memasukkan bola ke gawang tim lain pada saat menyerang, mengubah arah gerakan dengan cepat ketika kembali ke posisi masing–masing serta menghindari gangguan pada punggung..Penelitian ini adalah bentuk penelitian eksperimental yang akan menguji efektifitas dari pemberian trunk balance exercise dalam  meningkatkan  keseimbangan kinerja otot erector spine pada pemain futsal pemula,  pada penelitian ini sampel akan diberikan trunk balance exercise untuk meningkatkan keseimbangan kinerja otot erector spine pada pemain futsal pemula. Penelitian ini dilakukan selama 6 minggu  dan intervensi dilakukan sebanyak 18 kali selama periode penelitian. Sampel diukur dengan surface electromyography dengan mengukur kerja dari otot erector spine kanan dan kiri dengan menghitung proporsi kerja pada otot tersebut , di ukur pada sebelum intervensi kemudian dilakukan intervensi kemudian setelah dilakukan intervensi, sampel di ukur kembali untuk mendapatkan nilai hasil intervensi.Hasil dari pemberian trunk balance exercise menunjukkan nilai rerata pada sebelum perlakuan dengan nilai (83,82±2,94) % dan nilai rerata pada setelah perlakuan sebesar (96,74 ±2,39) %, dengan nilai probailitas pada sampel  adalah 0,000 (p<0,05) dan dinyatakan ada perbedaan yang signifikan pada penelitian tersebut. dan dapat dinyatakan secara analisis statistik ada perbedaan yang signifikan antara sebelum dan sesudah perlakuan yang dilakukan dan artinya pemberian trunk balance exercise dapat  meningkatkan  keseimbangan kinerja otot erector spine pada pengghobi futsal.
MENURUNKAN NYERI PADA OSTEOARTHRITIS GENU DENGAN MICRO WAVE DIATHERMY
Authors: Ikrom Al Hazmi Dhofirul Fadhil Dzil , Yuliana Sri
Published: February 2023

Advances in science and technology or digital developments are increasingly advanced today, making it easierfor people to get what they want without moving much, this condition is often encountered today. That way aperson's tendency to experience osteoarthritis due to an unhealthy lifestyle is often found. These factors willresult in the development of diseases experienced by the public due to biological, physical, chemical anddegenerative processes. In the case of osteoarthritis is often also referred to as a degenerative disease.Physiotherapy in this case will look at the effect of giving micro wave diathermy in cases of genu osteoarthritisin reducing pain. This research design is a randomized pre and post test group design. The sample in thisstudy was 10 people who experienced genu osteoarthritis and felt pain. The age of the sample in this studywas 40-60 years. The test used to collect pain data in this study was the visual analog scale / VAS. Where thesample is measured its VAS value before (0-session) and after treatment (6 sessions) on each subject. Theresults of the average VAS in the sample experienced a decrease in pain.