bluuebunny/crossref_metadata_2025 huggingface dataset:
Combined Prediction of PM10 Concentration at Smart Construction Sites Based on Quadratic Mode Decomposition and Deep Learning
Authors: Li Ming , Li Xin , Kang Kaikai , Li Qiang
Published: January 2025

The accurate prediction of PM10 concentrations at smart construction sites is crucial for improving urban air quality, protecting public health, and advancing sustainable development in the construction industry. PM10 concentrations at construction sites are influenced by the interaction of construction intensity and environmental meteorological factors, resulting in nonlinear and volatile data. To improve prediction accuracy, this paper presents a two-stage mode decomposition method that integrates Complementary Ensemble Empirical Mode Decomposition with Adaptive Noise (CEEMDAN) and Variational Mode Decomposition (VMD). This method is combined with a Bidirectional Long Short-Term Memory (BiLSTM) neural network, optimized using the Sparrow Search Algorithm (SSA), to establish a hybrid model for forecasting PM10 concentrations at construction sites. Initially, CEEMDAN decomposes the original sequence into several Intrinsic Mode Functions (IMFs). The sample entropy of each component is then calculated, and K-means clustering is used to group them. VMD is applied to further decompose the high-frequency components obtained after clustering. SSA is then employed to optimize the parameters of the BiLSTM network, which models all the components with the optimized predictive model. The predicted values of all components are aggregated to generate the final forecast. Real-time monitoring data from Construction Site A in Nanjing are used for case study validation. The empirical results demonstrate that the proposed hybrid prediction model outperforms comparison models on all evaluation metrics, offering a scientific foundation for sustainable and automated dust reduction decision-making at smart construction sites, thereby facilitating the shift toward greener, smarter, and more digitized construction practices.
Price Interaction Between Crude Oil, Selected Grains, and Oilseeds in South Africa
Authors: Ledwaba Kgabo Lucracia , Muchopa Chiedza L. , Belete Abenet
Published: January 2025

The dynamic interaction between crude oil prices and the prices of grains and oilseed is critical yet a complex issue in agriculture given the potential impact of the energy sector price fluctuations on production costs, transportation, and processing. This study explores the interactions between prices of crude oil, key grains, and oilseeds (maize, soybean, and wheat) in South Africa from 2018 to 2022. Utilising monthly data, this study employs the Auto-Regressive Distributed Lag (ARDL) model to assess the short-term and long-term relationships, and the Granger causality test to determine the causality directions. Results revealed a mixed long-term cointegration wherein crude oil prices and the prices of maize as well as soybean have a relationship, but no evidence of such a relationship exists for wheat prices. Additionally, no short-term effects were observed, suggesting that immediate fluctuations in crude oil prices do not influence the prices of maize, soybean, and wheat. Instead, short-term prices movements of the grains and oilseeds may be driven by other factors that could be of interest to policymakers. Furthermore, the Granger causality findings show no causality direction between prices of crude oil and the selected grain and oilseed. These findings challenge the presumed direct connection between energy and agricultural prices, thus offering policymakers a perspective to redirect their focus to formulate short-term price policy strategies that decrease dependability on crude oil to promote sustainability in the agricultural sector without disrupting the progress towards achieving Sustainable Development Goal 2 of ending hunger.
Bringing Sustainable Practices, Fashion Shows, and Sociological Insights Together to Reinvigorate Sustainable Fashion Education
Authors: Wang Mengyuan , Murphy Richard , Christie Ian
Published: January 2025

This study explores the intersection of sustainable fashion practices, fashion shows, and sociological insights to develop sustainable fashion education. It investigates how sustainable practices are integrated into the fashion industry and education programs. Moreover, it critically analyses the evolving role of the fashion show in a time when sustainability takes a central position. Additionally, this study shows the possibilities and problems presented by the emergence of virtual fashion experiences. The literature review investigates the difficulties the fashion industry faces when moving towards sustainability. It systematically explores a range of innovative solutions put forth by scholars and practitioners. Moreover, this report delves into the core principles of sociological perspectives, particularly in fashion sociology. It explores the emerging trend of virtual fashion, emphasising the essential role that fashion education plays in promoting sustainability awareness among designers, industry professionals, and consumers. Ultimately, this study aims to encourage the fashion industry towards a more sustainable future by decreasing the traditional tensions between sustainability and fashion. It highlights the urgent need for the industry to embrace sustainable practices and prioritise sustainability in fashion education.
Fusarium Head Blight in Argentina, a Profile of Produced Mycotoxins and a Biocontrol Strategy in Barley During Micro-Malting Process
Authors: Alaniz-Zanon María Silvina , Bossa Marianela , Rosales Cavaglieri Lorenzo Antonio , Palazzini Juan Manuel , Sulyok Michael , Chulze Sofía Noemí , Chiotta María Laura
Published: January 2025

Barley (Hordeum vulgare L.) is the second winter crop in Argentina. In the national market, grains are mainly destined to produce malt for beer manufacture. Fusarium species are common, causing Fusarium Head Blight (FHB) in barley, which generates yield and quality losses, as well as mycotoxin occurrence. The aims of this study were to determine (a) the incidence of the main species causing FHB in different locations of the barley-growing region of Argentina, (b) their ability to produce mycotoxins, and (c) the levels of deoxynivalenol (DON) and nivalenol (NIV) natural occurrence in grains at the harvest stage. Additionally, a strain of Bacillus velezensis was studied as a biocontrol agent in order to control F. graminearum sensu stricto and mycotoxin accumulation during the malting process, with the final objective being to reduce DON contamination in the beer manufacture chain. Fusarium graminearum ss was the most prevalent species causing FHB, with Fusarium poae being less distributed. Both species produced several mycotoxins, including NX-2 and NX-3, which is the first report of their production by strains isolated from barley in Argentina. Deoxynivalenol contamination was found in 95% of barley grains during the 2016 harvest season (mean: 0.4 mg/kg), while NIV contamination was present in 29% of samples (mean: 0.49 mg/kg). In the 2017 harvest season, 53.6% of grains were contaminated with DON (mean: 0.42 mg/kg), and 21% with NIV (mean: 0.8 mg/kg). Quantification of F. graminearum ss by real-time PCR during the micro-malting process showed that application of the biocontrol agent before the germination stage was the most effective treatment, with a 45% reduction in fungal DNA levels. Reduction in DON contamination (69.3–100%) in artificially infected grains with F. graminearum ss, was also observed. The present work contributes to the knowledge of FHB in Argentina and to the development of a strategy to control this disease and mycotoxin contamination in barley, promoting at the same time food security.
Genomic, Evolutionary, and Pathogenic Characterization of a New Polerovirus in Traditional Chinese Medicine Viola philippica
Authors: Chen Yuanling , Chen Gaoxiang , Yu Jiaping , Zhou Yali , Fei Shifang , Chen Haorong , Wu Jianxiang , Fu Shuai
Published: January 2025

Viola philippica, a medicinal herbaceous plant documented in the Chinese Pharmacopoeia, is a promising candidate for research into plant-derived pharmaceuticals. However, the study of newly emerging viruses that threaten the cultivation of V. philippica remains limited. In this study, V. philippica plants exhibiting symptoms such as leaf yellowing, mottled leaves, and vein chlorosis were collected and subjected to RNA sequencing to identify potential viral pathogens. A novel polerovirus, named Viola Philippica Polerovirus (VPPV), was identified in V. philippica. VPPV possesses a linear, positive-sense, single-stranded RNA genome consisting of 5535 nucleotides (nt) and encodes seven highly overlapping open reading frames (ORFs). Two potential recombination events were identified within ORF2, ORF3a, and ORF3, providing insights into the genetic diversity and evolution history of this novel polerovirus. An infectious cDNA clone of VPPV was successfully constructed and shown to infect Nicotiana benthamiana. Using a PVX-based heterologous expression system, the VPPV P0 protein was shown to trigger a systemic hypersensitive response (HR)-like reaction in N. benthamiana, indicating that P0 functions as the main pathogenicity determinant. These findings contributed to the detection and understanding of pathogenic mechanisms and control strategies for VPPV in V. philippica.
Single Dose of Attenuated Vaccinia Viruses Expressing H5 Hemagglutinin Affords Rapid and Long-Term Protection Against Lethal Infection with Highly Pathogenic Avian Influenza A H5N1 Virus in Mice and Monkeys
Authors: Yasui Fumihiko , Munekata Keisuke , Fujiyuki Tomoko , Kuraishi Takeshi , Yamaji Kenzaburo , Honda Tomoko , Gomi Sumiko , Yoneda Misako , Sanada Takahiro , Ishii Koji , Sakoda Yoshihiro , Kida Hiroshi , Hattori Shosaku , Kai Chieko , Kohara Michinori
Published: January 2025

Background/Objectives: In preparation for a potential pandemic caused by the H5N1 highly pathogenic avian influenza (HPAI) virus, pre-pandemic vaccines against several viral clades have been developed and stocked worldwide. Although these vaccines are well tolerated, their immunogenicity and cross-reactivity with viruses of different clades can be improved. Methods: To address this aspect, we generated recombinant influenza vaccines against H5-subtype viruses using two different strains of highly attenuated vaccinia virus (VACV) vectors. Results: rLC16m8-mcl2.2 hemagglutinin (HA) and rLC16m8-mcl2.3.4 HA consisted of a recombinant LC16m8 vector encoding the HA protein from clade 2.2 or clade 2.3.4 viruses (respectively); rDIs-mcl2.2 HA consisted of a recombinant DIs vector encoding the HA protein from clade 2.2. A single dose of rLC16m8-mcl2.2 HA showed rapid (1 week after vaccination) and long-term protection (20 months post-vaccination) in mice against the HPAI H5N1 virus. Moreover, cynomolgus macaques immunized with rLC16m8-mcl2.2 HA exhibited long-term protection when challenged with a heterologous clade of the HPAI H5N1 virus. Although the DIs strain is unable to grow in most mammalian cells, rDIs-mcl2.2 HA also showed rapid and long-lasting effects against HPAI H5N1 virus infection. Notably, the protective efficacy of rDIs-mcl2.2 HA was comparable to that of rLC16m8-mcl2.2 HA. Furthermore, these vaccines protected animals previously immunized with VACVs from a lethal challenge with the HPAI H5N1 virus. Conclusions: These results suggest that both rLC16m8-mcl2.2 HA and rDIs-mcl2.2 HA are effective in preventing HPAI H5N1 virus infection, and rDIs-mcl2.2 HA is a promising vaccine candidate against H5 HA-subtype viruses.
Effect of Time and Temperature on the Detection of PRRSV RNA and Endogenous Internal Sample Control in Porcine Tongue Fluids
Authors: Machado Isadora F. , Osemeke Onyekachukwu H. , Doolittle Kent , Moura Cesar A. A. , Galina Pantoja Lucina , Trevisan Giovani , Gauger Phillip , Linhares Daniel C. L.
Published: January 2025

Population-based sampling has improved pathogen monitoring in the US swine industry by increasing sensitivity while reducing costs. Postmortem tongue fluids (TF) have emerged as a practical option for monitoring porcine reproductive and respiratory syndrome virus (PRRSV) in breeding herds, but limited data exist on optimal storage conditions. This study evaluated PRRSV RNA detection via RT-qPCR in TF samples under various storage times, temperatures, and viral loads. Additionally, the porcine endogenous reference gene (internal sample control, ISC) was assessed for monitoring sample quality. Three studies were conducted: Study 1 compared fresh TF samples to freeze–thaw TF samples, with significantly lower cycle threshold (Ct) values in fresh samples. Studies 2 and 3 evaluated PRRSV RNA stability across six time points (0 to 336 h) and four temperatures (−20 °C, 4 °C, 22 °C, and 34 °C). At 4 °C, Ct value variation was minimal (≤1.1) over 14 days (336 h), with no significant changes within 48 h. In contrast, storage at 22 °C and 34 °C resulted in increased Ct values. The ISC RNA showed similar stability patterns, maintaining quality at 4 °C but degrading at higher temperatures. In conclusion, storing TF at ≤4 °C for up to 14 days for PRRSV and ISC RNA detection is the best scenario, ensuring optimal diagnostic quality.
Tidal Effects on Dissolved Organic Matter Dynamics in a Brackish Water Front Adjacent to Yangtze River Estuary
Authors: Wang Yasong , Peng Niting , Liu Zhiliang , Liu Liang , Pan Sishang , Duan Dayu , Xu Yunping
Published: January 2025

A brackish water front, where river water meets seawater, is a hotspot for biogeochemical processes. In this study, we examined the quantity and composition of dissolved organic matter (DOM) over a 24 h tidal cycle at a brackish water front near the Yangtze River estuary. Utilizing elemental analysis, fluorescence and ultraviolet spectroscopy, and ultra-high-resolution mass spectrometry, we observed rapid fluctuations in DOM throughout the tidal cycle. The dissolved organic carbon (DOC) and total nitrogen (TN) concentrations ranged from 0.70 to 1.5 mg/L and 0.43 to 0.94 mg/L, respectively. Water samples during low tide exhibited a higher fractional abundance of CHON (17.2 ± 0.1% vs. 14.6 ± 0.4%), CHOS (14.6 ± 4.5% vs. 9.1 ± 3.1%), and CHONS (1.6 ± 0.5% vs. 0.5 ± 0.3%) formulas, and a higher aromatization and average molecular weight, which is consistent with a stronger terrestrial influence. In contrast, at high tide, the water samples contained a greater abundance of CHO compounds (75.7 ± 3.8% vs. 66.5 ± 4.1%), a humic-like fluorescent C1 component, and carboxyl-rich alicyclic molecules (CRAMs), indicating a greater release of refractory DOM from resuspended sediments. However, variations in the DOC concentrations and several optical spectral parameters did not correlate with the changes in the salinity and tidal height. The results of the principal component analysis revealed different controls on specific fractions of DOM that are related to variable DOM sources or biogeochemical processes. The complexity of DOM dynamics underscores the necessity of elucidating DOM compositions at varying levels to enhance our understanding of carbon cycling in estuarine and coastal ecosystems.
January 10 – Houseplant Appreciation Day
Authors:   SBHI RR Kerch City Children Hospital, Rybachok O. A.
Published: January 2025

Which month of the year is the busiest for holidays and celebrations? Of course, January, you can
easily answer, and you will be absolutely right. The New Year holidays usually last more than a week, we spend a lot of time with our family and friends, and the most active individuals do not imagine themselves locked within four walls and enjoy communication with nature. But January is not rich in professional medical holidays: probably because cheerful holidaymakers prefer not to get sick on these days. It was all the more interesting to learn that on January 10, it is customary worldwide to celebrate an unusual date – the Houseplant Appreciation Day.
This holiday was approved by the initiative of the Gardener’s Network, which provided an official opportunity to
remind people of the benefits of the indoor plants around us. It turns out that small representatives of the flora are capable of not only pleasing the eye with their beauty, but also helping in the treatment of various diseases.
Managing the product range of an industrial enterprise in the context of digitalization
Authors:   FSBEI HE Ural State University of Economics, Ekaterinburg, Kondratenko. Yu. N.
Published: January 2025

The article discusses approaches and methods for managing the product range at industrial
enterprises, identifies problems in the use of digital technologies on the case of one of the largest industrial enterprises in the Sverdlovsk Region, suggests ways to improve the efficiency of product range management through the integration of the systems and technologies used into a single PLM system,
and makes recommendations on the choice of PDM systems.
Fe-supported perlite applied for the degradation of Rhodamine B dye by Heterogeneous Fenton reaction
Authors: Oliveira Aguiar Perez Jessica , Tuono Martins Xavier Gabriela , Felix Bitencourt Gustavo , Dos Santos Andrade Luana , Alves Carvalho Wagner , Jesus Olortiga Asencios Yvan
Published: January 2025

This study aimed to evaluate a technique of Fe ion impregnation on perlite mineral and assess its behavior in a heterogeneous Fenton-like reaction, at room temperature and under acidic and alkaline conditions in the removal of Rhodamine B dye. For the catalyst preparation, a suspension of heptahydrated ferrous sulfate (FeSO4.7H2O) was used, followed by thermal treatment (calcination). Different doses of H2O2  (35% v/v) were applied to evaluate dye removal rates. Fe leaching in reaction media was analyzed. Rhodamine B removal at pH 4, 7, 9, 10, and 11 had the respective removal rates of 99.8%, 57.4%, 73.1%, 77.5%, and 96.9% in 240 minutes of reaction. At pH 12, there was 99.7% removal in 110 minutes of reaction. Reactions performed with low dosages of hydrogen peroxide showed, at pH 4 and 11, removal percentages of 95.8% and 90.2%, respectively, in 150 minutes of reaction. Under the same conditions, at pH 12, the removal percentage was 98.6% in 105 minutes. The synthesized catalyst exhibited satisfactory activity under acidic and alkaline conditions, for three cycles, showing promise for applications in heterogeneous Fenton reactions on a large scale.
Impactos do diagnóstico tardio no desenvolvimento cognitivo e psicossocial em pacientes com Transtorno do Espectro Autista (TEA)
Authors: Abrantes Ester Emanuele , Silva Ana Karolina Alves da , Ramalho Marianna Adijuto de Oliveira , Guedes Tâmara Albuquerque Leite
Published: January 2025

Objetivo: Relatar os impactos do diagnóstico precoce e tardio no desenvolvimento cognitivo e psicossocial em pacientes com TEA. Métodos: Trata-se de uma pesquisa do tipo exploratório-descritivo, realizada em centros de referência em atendimento ao paciente com TEA em João Pessoa, na Paraíba. O público-alvo foram crianças com diagnóstico tardio, após os 36 meses, e a ferramenta utilizada foi um questionário semiestruturado com 16 perguntas que abordavam características sociais e cognitivas. Resultados: Através de uma análise descritiva simples foram analisados os questionamentos onde foi observado prevalência no sexo masculino e diagnóstico entre os 3 e 7 anos de idade. Quanto as características sociais, o contexto mais afetado foi o convívio social e familiar. No cognitivo, o maior impacto foi na alfabetização e, consequentemente, na atenção, concentração e articulação das palavras. Conclusão: Conclui-se a necessidade contínua de investigação do tema, a fim de acompanhar a evolução da implementação de políticas públicas e formação de trabalhadores da saúde preparados para tornar o diagnóstico mais precoce possível, pois foi notório os impactos cognitivos e psicossociais com atraso do diagnóstico.
O papel dos agentes comunitários de saúde no combate à desinformação: desafios e oportunidades em diálogo com estudantes de Medicina
Authors: Frezer Amanda , Belmonte Isadora Bortolon , Bogus Eduardo Muchalak , Leite Juliana Murta , Soares Luiza Barbosa , Oliveira Rosagela Ziggiotti de
Published: January 2025

Embora um fenômeno antigo, a desinformação em saúde foi intensificada na pandemia e seu combate continua sendo um desafio para os trabalhadores da saúde pública. Nesse contexto, acadêmicos de medicina da Pontifícia Universidade Católica de Curitiba, PR, mediaram uma roda de conversa sobre a temática com Agentes Comunitários de Saúde. Os participantes discutiram os impactos da desinformação na saúde das pessoas e nos princípios do SUS. A atividade permitiu identificar os principais desafios enfrentados pelos profissionais no combate à desinformação e a importância da educação permanente para qualificar sua atuação junto à população.
Prevalência e resistência antimicrobiana de Streptococcus agalactiae em gestantes da Rede Pública de Barreiras, Bahia
Authors: Silva Sarah Moura da , Mendes Daniela Silva , Bortoli Gabriela Lopes De , Matos Giovana Carvalho Maganhoto de , Menezes Lainara Hanna Bastos da Silva , Meneses Isabella Santos Barreto , Dobrachinski Marilissa Maciel Maineri , Dobrachinski Leandro
Published: January 2025

O Streptococcus agalactiae (EGB) é uma bactéria gram-positiva que coloniza o trato genital feminino e constitui uma das principais causas de infecções neonatais graves, como sepse e meningite. A colonização materna representa um fator de risco significativo para a transmissão vertical durante o parto, resultando em complicações perinatais. Este estudo investigou a prevalência e o perfil de resistência antimicrobiana de S. agalactiae em gestantes atendidas na rede pública de saúde de Barreiras, Bahia, além de fatores associados à colonização. Entre março e outubro de 2024, 200 gestantes entre a 35ª e a 37ª semana de gestação foram avaliadas. Amostras vaginais e retais foram coletadas para análise microbiológica, e a resistência a antimicrobianos foi determinada por difusão em disco. A prevalência de colonização foi de 41,5%, com resistência elevada à tetraciclina (81,9%) e eritromicina (25,3%), enquanto todos os isolados foram suscetíveis à penicilina, ampicilina, cefazolina e ceftriaxona. Fatores sociodemográficos, como idade entre 20-30 anos, estado civil e escolaridade, e aspectos obstétricos, como corrimento vaginal e infecções urinárias, mostraram associação com a colonização. Os resultados ressaltam a importância do monitoramento contínuo da prevalência e resistência antimicrobiana do EGB, especialmente em regiões com características específicas, como Barreiras. A identificação precoce e a profilaxia intraparto são essenciais para prevenir a transmissão vertical e complicações neonatais. Ademais, o estudo reforça a necessidade de políticas públicas voltadas à triagem universal e ao uso racional de antimicrobianos.
Avaliação da Segurança Alimentar e Nutricional em trabalhadores de um complexo industrial no município do interior do estado de São Paulo: um estudo transversal
Authors: Dorta Murillo Cesar Holtz , Aranha Flávia Queiroga
Published: January 2025

Considerando a relevância da Segurança Alimentar e Nutricional (SAN) no ambiente de trabalho, especialmente em complexos industriais, verifica-se a necessidade de avaliar as condições alimentares e o impacto das refeições fornecidas no local de trabalho na alimentação diária dos funcionários. Objetiva-se investigar a prevalência de SAN e Insegurança Alimentar (IA), bem como a percepção da importância da refeição realizada no Serviço de Alimentação (SA) entre trabalhadores de um complexo industrial em São Paulo. Para tanto, realizou-se um estudo transversal com 175 participantes que responderam a um questionário contendo a Escala Brasileira de Insegurança Alimentar (EBIA), questões sociodemográficas e uma avaliação sobre a importância das refeições no SA. Os dados foram analisados com auxílio do Excel e do software R. Desse modo, observou-se que 70,3% dos participantes estavam em SAN, enquanto 29,7% apresentavam algum grau de IA. A refeição no SA foi considerada muito importante ou importante por 83,43% dos trabalhadores, indicando sua relevância para a alimentação diária. Conclui-se que, embora a maioria dos trabalhadores esteja em SAN, a refeição no SA desempenha um papel essencial na alimentação diária, especialmente para aqueles em situação de IA. Estudos futuros devem investigar a relação entre características sociodemográficas, IA e a qualidade nutricional das refeições fornecidas.
Tuberculose laríngea em paciente hídiga - um relato de caso
Authors: Merlos Fernando , Merlos Priscila Gabriella Carraro , Oliveira Gabriela Rossetto de
Published: January 2025

Objetivo: Relatar caso de paciente hígida com Tuberculose laríngea primária erroneamente diagnosticada. Método: Estudo descritivo, tipo relato de caso através da coleta de informações contidas em prontuário do Hospital Regional Hans Dieter Schmidt, localizado no município de Joinville – Santa Catarina. Para a revisão bibliográfica, foi realizada uma pesquisa envolvendo a análise de artigos digitais disponíveis em plataformas de bases de dados como Scientific Electronic Library Online (SCIELO), PubMed e Google Acadêmico. Resultado: Relata-se o caso de uma paciente de 30 anos com quadro de disfonia intensa, associado à dor na garganta, odinofagia e tosse secretiva. Ao exame físico Laringoscópio notável a presença de leucoplasia em cordas vocais. Durante o episódio, foi erroneamente diagnosticada como Infecção Fúngica por Candida albicans e posteriormente como Doença de Refluxo Gastroesofágico. Após sete meses sem significativas melhoras a repetição da Laringoscopia mostrou-se sugestivo de doença granulomatosa, cultura positiva para Micobactéria e PCR com identificação do complexo Mycobacterium tuberculosis, confirmando o diagnóstico de Tuberculose Laríngea. Discussão: Tuberculose Laríngea raramente é apontada como diagnóstico pela sintomatologia descaracterizada apresentada, com a mudança do padrão clínico ao longo dos anos frequentemente é confundida com outras patologias laríngeas. Conclusão: Deve-se enquadrar os novos aspetos clínicos, diagnósticos e terapêuticos da tuberculose laríngea e alertar para considerar esta doença como uma hipótese diagnóstica em casos de manifestações clínicas.
Avanços em biomarcadores plasmáticos e do líquido cefalorraquidiano para a detecção precoce da doença de Alzheimer
Authors: Vieira Lemuel Kalil da Silva , Silva Giulia Germano de Azevedo , Oti Isabella Ayka Melo , Vale Tereza Cristina Barbosa Ribeiro do , Gurgel Aneybh Oliveira , Calixto Renata Alcântara , Mesquita Dominique Cardoso Passos , Castro Isadora Fontenelle Carneiro de , Araújo Eva Karem Morais de , Passos Raissa Marinho Lima dos , Lemos Caio Vinícius de Carvalho , Sousa João Victor Costa Lacerda de , Junior Fernando Pinheiro Costa , Galvão Natália Feitosa Teixeira , Barroso Sara Miranda da Silva , Bringel Dayane de Oliveira Martins , Oliveira Mayara Maia , Bringel Ingryd de Oliveira Martins , Abdala Olivia Rachel Fernandes , Freire Maria Luyza de Maranhão Condé
Published: January 2025

A Doença de Alzheimer (DA) é a principal causa de demência em idosos, causada pelo acúmulo de β-amiloide e emaranhados neurofibrilares no cérebro. Novas terapias, como anticorpos monoclonais, destacam a importância de identificar a doença cedo. O futuro do tratamento da DA depende de biomarcadores acessíveis e não invasivos. Este estudo revisou a literatura sobre biomarcadores na Doença de Alzheimer (DA) em bases de dados de 2021 a 2024. Incluiu estudos que avaliaram biomarcadores sanguíneos, como β-amiloide e tau, com desfechos clínicos. A busca nas bases de dados resultou em 351 artigos. Após a aplicação dos critérios de elegibilidade, 6 artigos foram analisados e 4 selecionados. A pesquisa destacou a importância de biomarcadores como p-tau e β-amiloide no diagnóstico precoce e acompanhamento da Doença de Alzheimer (DA). O uso de algoritmos e biomarcadores, como GFAP e YKL-40, mostrou potencial para reduzir procedimentos invasivos e melhorar a identificação precoce da doença, facilitando intervenções terapêuticas e ensaios clínicos. Contudo, ainda há desafios éticos e a necessidade de mais pesquisas para validar o uso desses biomarcadores na prática clínica. Biomarcadores como p-tau e GFAP são fundamentais no diagnóstico precoce e monitoramento da Doença de Alzheimer, ajudando a identificar riscos e possibilitar intervenções preventivas. Mais pesquisas são necessárias para validar esses biomarcadores na prática clínica.
Efeito da liberação miofascial e dry needling na dor, força muscular, amplitude de movimento e temperatura superficial dos músculos isquiotibiais em praticantes de futebol: estudo piloto
Authors: Penteado Leonardo Solano , Gomes Guilherme Gallo Costa , Fabrin Saulo Cesar Vallin , Manoel Lucas Sartori , Siéssere Selma , Regalo Simone Cecílio Hallak , Verri Edson Donizetti
Published: January 2025

Este estudo observacional, experimental e piloto investigou e comparou as duas abordagens terapêuticas como o dry needling (n=4) e liberação miofascial (n=4) no comportamento da dor, amplitude de movimento, força muscular e repercussões termográficas dos músculos isquiotibiais de atletas amadores de futebol. Os participantes foram submetidos a avaliação da amplitude de movimento pelo goniômetro convencional manual. A força muscular dos isquiotibiais foi usado o Hand-held Dinamometer Laffayette Instrument. Para avaliar a temperatura superficial muscular foi usado a câmera FLIR C3. Por fim, para avaliar a dor foi usado a Escala Visual Analógica de Dor. Os dados foram analisados pelo Teste t-pareado (p ​< ​0,05). Diferenças significativas foram observadas no grupo dos indivíduos que passaram por aplicação de dry Needling e liberação miofascial, apresentaram diminuição da dor e aumento da ADM com diferença significativa (p<0,05) pós-intervenção. Não houve diferença significativa na avaliação entre as técnicas. A liberação miofascial e o Dry Needling apresentaram defechos semelhantes com o aumento da amplitude de movimento de diminuição da dor contribuindo para melhor desesempenhos dos praticantes. Mas em relação a força e temperatura superficial dos músculos isquitibiais não foi observado diferença significativa. Contudo, mais estudos devem ser desenvolvidos para investigar o potencial efeito e as diferenças individuais das técnicas na periodização de treinamento.
Consumo de dexametasona em um hospital municipal antes, durante e depois da pandemia COVID-19
Authors: Santana Janaina , Oliveira Matheus Deda de , Souza Eloísa Portugal Barros Silva Soares de , Pietro Giuliano Di
Published: January 2025

Introdução: Em 2020, o mundo enfrentava uma pandemia de COVID-19, causada pelo SARS-CoV-2, tendo sintomas como febre, cansaço e tosse seca, podendo ocasionar perda temporária do olfato, com agravamentos respiratórios, desencadeando internações e mortes. Segundo o estudo da RECOVERY, foi sugerido que a dexametasona deveria ser usada para tratar COVID-19 grave. Objetivos: Esta pesquisa teve como objetivo identificar as mudanças nas prescrições de dexametasona ocorridas durante o enfrentamento da pandemia de Covid-19 com relação em um hospital municipal de Aracaju. Metodologia: Foi realizado um levantamento quantitativo, exploratório em relação a utilização do corticoide durante o período entre 2019 a 2022. Resultados: Diante da importância do acompanhamento e das competências dentro das organizações de saúde, o presente trabalho buscou por analisar as mudanças ocorridas neste período, quantificando e estabelecendo uma relação direta sob o consumo do medicamento dexametasona com o panorama epidêmico. Conclusão: Dessa forma, foi possível observar as mudanças, tanto na quantidade utilizada de dexametasona, quanto nas suas indicações clínicas na unidade de saúde pesquisada.
ANALISIS PERAN MEGA, MACRO, DAN MICRO INFLUENCER DALAM PROMOSI PRODUK KECANTIKAN (STUDI PADA KONTEN INFLUENCER DI TIKTOK)
Authors: Marchella Sinolungan  , Suryanto  , Arianis Chan
Published: January 2025

This research discusses the role of mega, macro, and micro influencers in promoting beauty products through the TikTok platform using the AISAS (Attention, Interest, Search, Action, and Share) approach. The purpose of this study is to analyze the role of influencers in attracting attention, building interest, encouraging information search, triggering purchases, and encouraging audiences to share promotional content. This research uses a descriptive qualitative method with a literature study approach and content analysis from TikTok social media. The results show that each level of influencer has a significant role in increasing consumer buying interest. Micro-influencers can reach specific audiences with authentic content, macro-influencers are trusted to provide in-depth reviews that are educative, while mega-influencers help increase brand awareness with a wider audience reach. This promotional strategy is proven to increase engagement, build trust, and impact sales of beauty products
SOCIAL MEDIA INFLUENCER AUTHENTICITY MENDORONG NIAT BELI KONSUMEN PADA PRODUK DESIGNER BRANDS MELALUI SOCIAL MEDIA INFLUENCER INSPIRATION
Authors: Dexi Triadinda  , Dwi Epty Hidayati
Published: January 2025

The purpose of this study is to analyze the influence of Social Media Influencer Authenticity on Purchase Intention of Designer Brand Products with Social Media Influencer Inspiration as a mediator. This study uses a quantitative method. The data used are primary data and secondary data. The research instrument was distributed to 140 respondents, the calculation of the number of samples using the Lamseshow method. The sampling method was collected by purposive sampling. Data analysis in this study used SEM PLS (Structural Equation Modeling). The results of the study stated that SMI Authenticity does not have a direct effect on consumer purchase intention on designer brand products, but its influence is indirect and mediated through SMI Inspiration
PENINGKATAN DAYA SAING MELALUI PLATFORM SHOPEE DENGAN ANALISIS SWOT (STUDI KASUS : MTRSTORE.ID)
Authors: Sahlul Haq Robbani  , Aries Kurniawan
Published: January 2025

MTRSTORE.ID is a thrift shop business operating in the fashion industry, offering imported thrift products such as jeans, chinos, and cargo pants. This business was chosen due to the rapid trend growth in the sector, particularly among teenagers. This study aims to analyze the competitiveness of MTRSTORE.ID, a thrift shop operating on the Shopee e-commerce platform, using the SWOT analysis approach. In the context of globalization and advancements in information technology, businesses like MTRSTORE.ID face challenges to remain relevant and competitive in an increasingly tight market. The analysis results show that MTRSTORE.ID has strengths, including high sales potential through Shopee's large user base and attractive promotions. However, the business also faces weaknesses, such as intense competition and high administrative costs. Opportunities to boost sales include participating in discount programs and utilizing Shopee's advertising features, while threats such as price competition and challenges in maintaining product quality need to be addressed. This research employs a qualitative methodology with a case study approach. It recommends that MTRSTORE.ID implement these strategies to enhance its competitiveness on Shopee, utilizing the SWOT (Strengths, Weaknesses, Opportunities, Threats) analysis framework.
EVALUASI EFEKTIVITAS SERVANT LEADERSHIP DAN MOTIVASI KERJA TERHADAP KINERJA PERSONIL SATPAS DALAM MENINGKATKAN PELAYANAN PENERBITAN SIM DI WILAYAH HUKUM POLRESTABES PALEMBANG
Authors: Novi Indah Earlyanti  , Fausiah Tamal  , Yoeliastuti
Published: January 2025

This research is motivated by the quality of the National Police's Human Resources (HR) and public services which are not yet optimal, Standard Operating Procedures (SOP) which are still complicated, vocational school-based assessments which are still not running well, the integrity of officers is weak, and leadership style is something that must continue to be improved in the SIM service. The purpose of this research is to determine the evaluation of the effectiveness of servant Leadership and work motivation on the performance of Satpas personnel in improving SIM issuance services in the Palembang Police Legal Area. The concept or theory of Servant Leadership (X1) from Yulk (2016:62), work motivation (X2) is explained by Uno's theory (2017:53) and performance (Y) uses Robbins' theory (2015:76). This research uses quantitative methods with a cross-sectional research design. The target population in this research is the Palembang Police Traffic Unit personnel, 176 people who work at the Palembang Police. Meanwhile, the target population is 36 Satpas personnel. The data collection technique uses a 50-item questionnaire with a Likert scale. The data analysis technique used is Multiple Linear Regression Analysis. The research results show that the calculated F value is 425.013 with a significance level of 0.000. The t value is 7.538 with a significance value between Servant Leadership and the performance of Satpas personnel in improving SIM issuance services of 0.000. The multiple linear regression equation is ????̂ = 0.453 + 0.615X1 + 0.241
Arab countries and efforts in investing in renewable energy – an analytical study of mechanisms to enhance cooperation for the expansion of renewable energy systems use
Authors: Hicham Benazza , Ali Boukhari , Laamari Imane , Samah Boudoukha , Mohamed Trifa
Published: January 2025

The expansion of energy consumption cannot proceed without limits, due to the finite nature of conventional energy sources. The warning bell has been sounded, and most Arab governments have begun their relentless efforts to address the increasing energy consumption and find possible solutions and alternatives. The most appropriate and optimal solution, which has been acknowledged by all countries around the world, is to establish a sustainable energy system within the framework of implementing a long-term strategy that allows for the development and growth of various renewable energy sources at the local and national levels. In this context, this research aims to address the following issue: What are the efforts of Arab countries towards investing in renewable energy? This study relies on a descriptive-analytical approach, and the findings emphasize that Arab countries are making significant efforts to enhance cooperation for expanding the use of renewable energy systems.
The auditor and his role as a watchdog on the interests of stakeholders: the case of transactions between related parties and regulated agreements in Algeria
Authors: Ayachi Fela , Mouffok Benichou
Published: January 2025

Regulated agreements and transactions between related parties are common practices in the life of companies. However, it can be misused by the parties controlling the company or managers to the detriment of its shareholders and stakeholders. Directors may also be tempted to put their personal interests ahead of the company's corporate interest. In addition to the objective of transparency ensured by the traceability required by formalism on regulated agreements through the Commercial Code, the IASB has developed IAS 24, which aims to improve the transparency of transactions between related parties by providing relevant information on related parties in order to facilitate the control of corporate governance structures. Also, for their part, the statutory auditors draw up two reports throughout the process, one addressed to the Board of Directors to enable them to authorize the agreement, the other called the "Special Report" to the General Meeting on the authorized agreements.
Some nitroborazines – A DFT treatment
Authors: Türker Lemi
Published: January 2025

Borazine is an inorganic analogue of benzene and its nitro derivatives recently found some applications. Presently some nitro derivatives of borazine have been considered within the restrictions of density functional theory at the level of B3LYP/6-311++G(d,p) level. It has been found that all the structures of consideration have thermo chemically exothermic heat of formation and favorable Gº values at the standard states and energetically stable. Various structural and quantum chemical data have been collected and discussed, including UV-VIS spectra. Also the NICS (0) data have been obtained for the species which suggest that the structures are aromatic irrespective of whether nitro groups are linked to nitrogen or boron atoms.
Gestión del talento humano y satisfacción laboral
Authors: Minaya-Serna Aníbal Edwin , Ruíz-Gómez Andrés Alberto , Concha-Huarcaya Manuel Alejandro , Alva-Olivos Manuel Antonio
Published: January 2025

El objetivo general del estudio fue determinar la relación entre la gestión del talento humano y la satisfacción laboral de las enfermeras del Hospital Víctor Ramos Guardia, Huaraz. El estudio según su carácter fue correlacional, la población estuvo constituida por 120 profesionales de enfermería. Se evidencia relación estadística entre la GTH y la satisfacción laboral en las enfermeras, con un valor de p= 0,00002. La GTH se considera como uno de los aspectos importantes a impulsar a nivel de las organizaciones, sobre todo en la atención de salud donde se trata directamente con los individuos, es por ello por lo que el usuario interno debería tener las mejores condiciones de trabajo para que de esta manera se sienta cómodo al desarrollar sus labores y esto se vea reflejado en la calidad con que se le atiende al usuario externo de los establecimientos de salud
El desarrollo socio-emocional: Un acercamiento hermenéutico desde la música
Authors: Acosta-Montiel Yaneth Patricia
Published: January 2025

En la actualidad, se considera la música una herramienta necesaria para la educación, ya que no solo enriquece la vida de los estudiantes a nivel artístico, sino que también tiene un impacto positivo en su desarrollo socioemocional. A partir de esta premisa, se despliega este artículo con el propósito de develar hermenéuticamente categorías teóricas que resignifican a la música como herramienta para el desarrollo socioemocional de los estudiantes de la Institución Educativa Palo Alto, de Colombia.  El mismo es una investigación interpretativista, guiada por el método fenomenológico hermenéutico con un diseño de metodologías cualitativas. Finalmente, se puede enunciar que el proceso hermenéutico permitió el develamiento de dos categorías teóricas emergentes, con las que se puede resignificar la música en la medida de que se asuma como herramienta pedagógica y holística, con la que se puede activar el desarrollo de los procesos socioemocionales en los estudiantes desde tempranas edades
Digitalización en la gestión del impuesto al valor agregado en Ecuador: desafíos y oportunidades
Authors: Vizhñay-Aguilar Lorena del Carmen , Zapata-Sánchez Pedro Enrique
Published: January 2025

El estudio aborda la digitalización en la gestión del Impuesto al Valor Agregado (IVA) en Ecuador, evaluando el conocimiento, percepciones y desafíos de los contadores de empresas bajo el régimen general. De tipo descriptivo y se aplicó un cuestionario de 25 ítems como principal instrumento de recolección de datos. Los resultados revelan un nivel medio de conocimiento digital del IVA, con una percepción positiva sobre su impacto. Sin embargo, existe preocupación por la preparación de las empresas para la transición digital, así como por la eficacia de las estrategias gubernamentales y los obstáculos regulatorios. Se destaca la necesidad de educación digital, colaboración público-privada y políticas fiscales adaptativas. En conclusión, la digitalización del IVA presenta beneficios potenciales, así también desafíos que requieren acciones concertadas para una implementación efectiva y equitativa.
Surface roughness assessment of zinc oxide nanostructures formed on biomedical steel
Authors: Estrada-Martínez Fortino Fabián , Melo-Máximo Dulce Viridiana , Arzate-Vázquez Israel , Vega-Morón Roberto Carlos
Published: January 2025

This investigation explores the effect of hydrothermal time on the topographical
characteristics of zinc oxide nanostructures-based coating formed on AISI 316L
steel. First, a Zn adhesion layer was deposited and later a ZnO film. Next, the ZnO
nanostructures were grown by the hydrothermal method at a temperature of 90 °C
for 60 and 120 minutes. Elemental analysis was conducted at the surface and its
topographic characteristics were assessed by atomic force microscopy. After
images acquisition of the surface of the samples, arithmetic roughness (Ra), root
mean square roughness (Rq), kurtosis (Rk) and skewness (Rsk) were determined.
The arithmetic roughness Ra varied from ~26 nm to ~41 nm when hydrothermal
time increased from 60 to 120 min, whereas Rq increased from ~35 nm to ~53 nm.
Regarding the kurtosis and skewness parameters, when varying the hydrothermal
time, a decrease in their values was found.
Expansion and improvement of modular workstation for advanced PLC analysis and operation
Authors: Rodríguez-Franco Martín Eduardo , Jara-Ruiz Ricardo , Zacarías-Rodríguez Luis Gerardo , López-Álvarez Yadira Fabiola
Published: January 2025

This work provides continuity to the development of a modular workstation for the
advanced operation of the programmable logic controller (PLC), through
incorporation of the functions of master-slave communication, proportionalintegral-derivative (PID) controller and high-speed counters (HSC); and its use as
a support element for teaching process of related topics. The operation of the
workstation constituted from the integration of a speed control system in a threephase alternating current motor is analyzed; whose test parameters are entered from
a graphical interface executed through a touch screen. Such application was
implemented through a communication network between controllers; in addition, it
uses a variable frequency drive (VFD) and an encoder as power and perception
elements, respectively. The performance observed during the tests carried out
confirms an adequate follow-up of assigned parameters, by reaching and settling
real response of system in these. While, with regard to the use of the developed
modular workstation as a teaching tool for analysis of advanced automation
solutions, its relevance is confirmed.
Doğanın Yapıbozumuna Karşı İyileştirici Güç Olarak Ekolojik Sanat
Authors: Özer Yıldız
Published: January 2025

İnsan-doğa ilişkisi, tarih boyunca farklı evrelerden geçmiştir. Başlangıçta, insanlar doğayı doğal kaynakları kullanarak ve koruyucu bir şekilde işleyerek benimsemiştir. Ancak, İnsanmerkezcilik, Aydınlanma Çağı ve Sanayi Devrimi ile birlikte, insan-doğa ilişkisi kökten değişime uğramıştır. İnsanın kendini doğanın üstünde bir varlık olarak görmesi beraberinde Sanayi devrimi ve aydınlanma düşüncesi, akılcılığı öne çıkararak doğayı bir sömürü nesnesi olarak görmeye yol açmıştır. Bu yaklaşımların ve gelişmelerin sonucunda, küresel boyutta bir ekolojik sorunlar ortaya çıkmıştır. Bu sorunlar, çevre bilincinin artmasına yol açmıştır ve 1960'lardan itibaren, ekoloji ve çevrecilik hareketleri ortaya çıkmıştır. Doğanın ekolojisinin insan faaliyetleri sonucu kirlenmesi ve ekolojik yapısının bozulması, sanatçıların bu konuya eğilmesine ve doğayı kurtarmak için doğal malzemelerle projeler geliştirmesine yol açmıştır. Ekolojik sanatçılar, sanatın ekolojik sorunlara dikkat çekme ve çözüm sunma potansiyelini kullanarak, toplumun ekolojik bilincini artırmaya ve ekolojik dengeyi yeniden sağlamaya çalışmışlardır. Ekolojik sanat uygulamalarının temel amacı, toplumu doğaya karşı bilinçlendirmek, tahrip olmuş alanları onarmak ve ekoloji konusunda kalıcı çözümler üreterek dünyanın ekolojik bütünlüğünü korumak olmuştur.
Sanatın nesnesi artık doğanın ta kendisidir ve aynı zamanda doğanın özne konumuna yeniden getirilmesidir. Bu yaklaşımlar, insanın doğayla olan ilişkisini yeniden düşünmeye, doğaya olan saygıyı artırmaya ve ekolojik dengeyi yeniden sağlamaya yöneliktir. Bu şekilde, sanat doğayı sadece bir kaynak değil, aynı zamanda bir yaşam alanı ve ortak bir miras olarak görme eğilimini yansıtması bakımından önemlidir.