bluuebunny/crossref_metadata_2025 huggingface dataset:
Trifluoroacetic Acid Hydroxylamine System as Organocatalyst Reagent in a One-Pot Salt Free Process for the Synthesis of Caprolactam and Amides of Industrial Interest
Authors: Manente F. , Pietrobon L. , Ronchin L. , Vavasori A.
Published: March 2021

In this work we studied the reactivity of the Trifluoroacetic acid hydroxylamine system in the one step salt free synthesis of amides from ketones. A particular regards was paid to the caprolactam synthesis because of its industrial relevance. Synthesis, reactivity and characterization of the hydroxylamine trifluoroacetate is given. Fast oximation reaction of several ketones was gained at room temperature (1 h of reaction quantitative conversion for several ketones). In the same reactor, by raising the temperature at 383 K, the Beckmann rearrangement of the so obtained oximes is easily accomplished in the presence of three equivalent of TFA. The possibility of obtaining the trifluoroacetate of the hydroxylamine with a modified nitric acid hydrogenation reactions was verified, too. Reuse of solvent and trifluoroacetic acid is easily achieved by distillation.

Graphical abstract

Salt free one-pot caprolactam and amides process catalyzed by CF3COOH, in the presence of NH2OH TFA as the oximation agent.
Evaluating the potential of soil management to reduce the effect of Fusarium oxysporum f. sp. cubense in banana (Musa AAA)
Authors: Segura-Mena R. A. , Stoorvogel J. J. , García-Bastidas F. , Salacinas-Niez M. , Kema G. H. J. , Sandoval J. A.
Published: March 2021

Fusarium oxysporum f. sp. cubense (Foc) causes Fusarium wilt in banana (Musa AAA). Foc Race 1 devastated the subgroup Gros Michel during the first half of the twentieth century. The Gros Michel was largely replaced by the resistant subgroup Cavendish in the 1950s. However, in the 1980s, Foc Tropical Race 4 started to spread affecting Cavendish bananas. No proper control measures have been found to deal with the disease. This paper re-takes an important research line from the 1950s to evaluate the potential of soil management for Fusarium wilt management. The role of soil properties on Fusarium wilt in bananas was studied in two greenhouse experiments. It was evaluated whether the influence of two main soil properties (pH and N) on Fusarium wilt is similar for Race 1 and Tropical Race 4. Two soil pH levels (lower than 5.2 and higher than 6.0) respectively ensured through acidification and liming; and three levels of N (ammonium nitrate, 33.5% N) weekly doses (low:0 N g, medium: 0.08 N g and high: 0.25 N g per plant) were achieved. The first experiment in Costa Rica confirmed the earlier results about the influence of soil pH and nitrogen on Fusarium wilt (Race 1) on Gros Michel bananas. The second experiment in The Netherlands evaluated the influence of pH and N on interactions between Foc (both Race 1 and Tropical Race 4) and Cavendish bananas. Results in both experiments showed that soil pH affected crop development and the disease. Besides, the interaction of the lower pH x the higher N accelerated the infection and reduced plant development. As such, the results showed that soil management has the potential to reduce the impacts of Fusarium wilt while dealing with Race 1 and Tropical Race 4 although it requires confirmation and further evaluation under field conditions.
Effectiveness of Community-Delivered Functional Power Training Program for Frail and Pre-frail Community-Dwelling Older Adults: a Randomized Controlled Study
Authors: Tou Nien Xiang , Wee Shiou-Liang , Seah Wei Ting , Ng Daniella Hui Min , Pang Benedict Wei Jun , Lau Lay Khoon , Ng Tze Pin
Published: March 2021

Translation of community-based functional training for older adults to reduce frailty is still lacking. We evaluated the effectiveness and implementation of a community-delivered group-based functional power training (FPT) program for frail older adults within their neighborhoods. A two-arm, multicenter assessor-blind stratified randomized controlled trial was conducted at four local senior activity centers in Singapore. Sixty-one community-dwelling older adults with low handgrip strength were randomized to intervention (IG) or control (CG) group. The IG underwent the FPT program (power and balance exercises using simple equipment) delivered by a community service provider. The 12-week program comprised 2 × 60 min sessions/week. CG continued usual activities at the centers. Functional performance, muscle strength, and frailty status were assessed at baseline and 3 months. Program implementation was evaluated using RE-AIM framework. The program was halted due to Coronavirus Disease 2019-related suspension of senior center activities. Results are reported from four centers, which completed the program. IG showed significantly greater improvement in the Short Physical Performance Battery test as compared to CG (p = 0.047). No effects were found for timed up and go test performance, muscle strength, and frailty status. The community program exhibited good reach, effectiveness, adoption, and implementation. Our study demonstrated that FPT was associated with greater improvement in physical function in pre-frail/frail participants as compared to exercise activities offered at local senior activity centers. It is a feasible intervention that can be successfully implemented for frail older adults in their neighborhoods.

Trial registration ClinicalTrials.gov, NCT04438876. Registered 19 June 2020–retrospectively registered.
Non-Boolean classical relevant logics II: Classicality through truth-constants
Authors: Øgaard Tore Fjetland
Published: March 2021

This paper gives an account of Anderson and Belnap’s selection criteria for an adequate theory of entailment. The criteria are grouped into three categories: criteria pertaining to modality, those pertaining to relevance, and those related to expressive strength. The leitmotif of both this paper and its prequel is the relevant legitimacy of disjunctive syllogism. Relevant logics are commonly held to be paraconsistent logics. It is shown in this paper, however, that both E and R can be extended to explosive logics which satisfy all of Anderson and Belnap’s selection criteria, provided the truth-constant known as the Ackermann constant is available.   One of the selection criteria related to expressive strength is having an “enthymematic” conditional for which a deduction theorem holds. I argue that this allows for a new interpretation of Anderson and Belnap’s take on logical consequence, namely as committing them to pluralism about logical consequence.
Promoting regulation of equal participation in online collaboration by combining a group awareness tool and adaptive prompts. But does it even matter?
Authors: Strauß Sebastian , Rummel Nikol
Published: March 2021

Unequal participation poses a challenge to collaborative learning because it reduces opportunities for fruitful collaboration among learners and affects learners’ satisfaction. Social group awareness tools can display information on the distribution of participation and thus encourage groups to regulate the distribution of participation. However, some groups might require additional explicit support to leverage the information from such a tool. Therefore, this study investigated the effect of combining a group awareness tool and adaptive collaboration prompts on the distribution of participation during web-based collaboration. In this field experiment, students in a university level online course collaborated twice for two-weeks (16 groups in the first task; 13 groups in the second task) and either received only a group awareness tool, a combination of a group awareness tool and adaptive collaboration prompts, or no additional support. Our results showed that students were more satisfied when the participation in their group was more evenly distributed. However, we only found tentative support that the collaboration support helped groups achieve equal participation. Students reported rarely using the support for shared regulation of participation. Sequence alignment and clustering of action sequences revealed that groups who initiated the collaboration early, coordinated before solving the problem and interacted continuously tended to achieve an equal distribution of participation and were more satisfied with the collaboration. Against the background of our results, we identify potential ways to improve group awareness tools for supporting groups in their regulation of participation, and discuss the premise of equal participation during collaborative learning.
Collaborative note-taking affects cognitive load: the interplay of completeness and interaction
Authors: Costley Jamie , Fanguy Mik
Published: March 2021

Studies showing improved learning performances for students who take notes collaboratively have speculated that sharing this task among group members may reduce the extraneous cognitive burden placed on each member. Therefore, a study (n = 171) was conducted in the context of a flipped scientific writing course to examine the effects of collaborative note-taking on student’s levels of cognitive load. Students in the course were divided into two groups, with members of the treatment group being directed to take collaborative notes in a shared online document and members of the control group receiving no such instructions. The study also measured the level of collaboration the collaborative note-takers engaged in, as well as the level of completeness of the notes that they produced. The results showed that, firstly, the treatment group reported higher levels of both germane and extraneous cognitive load compared to those of the control group, meaning that collaborative note-takers experienced higher levels of understanding of course content as well as increased confusion. Secondly, the level of collaboration was positively and significantly correlated with levels of germane load (understanding), but not with extraneous load (confusion). Thirdly, no correlation was found between completeness of notes and cognitive load. Accordingly, the authors suggest that collaborative note-taking is worthwhile, as the gains to students’ understanding of course content outweigh the disadvantages of increased confusion.
Breaking monologues in collaborative research: bridging knowledge systems through a listening-based dialogue of wisdom approach
Authors: Moreno-Cely Adriana , Cuajera-Nahui Darío , Escobar-Vasquez Cesar Gabriel , Vanwing Tom , Tapia-Ponce Nelson
Published: March 2021

The urgent need to address the sustainability issues of the Anthropocene requires a dialogue capable of bridging different knowledge systems, values, and interests. This dialogue is considered one of the most crucial challenges in collaborative research approaches. With this research, we seek to break with monologues in collaborative research by offering a decolonising methodological approach that combines the notion of dialogue of wisdom, communication theories and ethical principles of Andean philosophy. The methodological framework, the circle of dialogue of wisdom, is the result of an iterative action–reflection process developed in a North–South collaborative research project for territorial planning in Bolivia. Our praxis confirms the potentials offered by a listening-based dialogue for (i) dealing with knowledge–power relations in collaborative research projects, (ii) promoting mutual learning and knowledge co-creation between different knowledge systems, (iii) re-valuating local and Indigenous knowledge, and (iv) decolonising the society–science–policy dialogue.
Comments on: Recent advances in directional statistics
Authors: Huckemann Stephan F.
Published: March 2021

Inspired by this felicitous, highly concentrated and rather exhaustive review of a rapidly growing field, many larger research areas that warrant further investigation come to mind. In this comment, three areas are selected: fully satisfactory PCA on tori and polyspheres, harnessing linearity through Lie algebras underlying homogeneous spaces such as those for directional data, and statistical analysis based on critical points (e.g. mode and antimodes) of Fréchet $$L^p$$

L
p

-functions.
Chia Seed Oil Ameliorates Doxorubicin-Induced Cardiotoxicity in Female Wistar Rats: An Electrocardiographic, Biochemical and Histopathological Approach
Authors: Ahmed Akheruz Zaman , Mumbrekar Kamalesh D. , Satyam Shakta Mani , Shetty Prakashchandra , D’Souza Melanie Rose , Singh Varun Kumar
Published: March 2021

Doxorubicin (DOX) is a potent anti-cancer antibiotic that was widely used for treatment of various cancers. It produces free radicals which result in extreme dose-limiting cardiotoxicity. This study investigated the cardioprotective potential of chia seed oil, an active polyphenolic nutraceutical against doxorubicin-induced cardiotoxicity in Wistar rats. Twenty-four female Wistar rats were divided into four groups (n = 6) which consist of normal control, DOX control, test-A and test-B group. Animals were prophylactically treated with two different doses of test drug, i.e. chia seed oil 2.5 ml/kg/day and 5 ml/kg/day in test-A and test-B groups orally for 7 days. Doxorubicin (25 mg/kg; single dose) was administered intraperitoneally to DOX control, Test-A and Test-B animals on the seventh day to induce cardiotoxicity. ECG analysis was done before and after treatment. Besides ECG, CK, CK-MB, LDH, AST, MDA and GSH were analyzed. DOX had significantly altered ECG, CK, CK-MB, LDH, AST, MDA and GSH. Pre-treatment with chia seed oil significantly alleviated DOX-induced ECG changes and also guarded against DOX-induced rise of serum CK, CK-MB and AST levels. Chia seed oil alleviated histopathological alteration in DOX-treated rats. It also significantly inhibited DOX-induced GSH depletion and elevation of MDA. The present study revealed that chia seed oil exerts cardioprotection against doxorubicin-induced cardiotoxicity in female Wistar rats. Our study opens the perspective to clinical studies to precisely consider chia seed oil as a potential chemoprotectant nutraceutical in the combination chemotherapy with doxorubicin to limit its cardiotoxicity.
Exploring the relationship between mindfulness and rock-climbing: a controlled study
Authors: Wheatley Katherine A.
Published: March 2021

Mindfulness is a meditative practice that has received increasing attention within positive psychology as an effective tool to increase wellbeing and decrease anxiety. Previous research has demonstrated that rock-climbers have a higher endorsement of mindfulness and life satisfaction than the general population; yet to date, no research has empirically explored the relationship between mindfulness and rock-climbing. In the current study fifty-nine participants ($$ \overline{\mathrm{x}} $$

x
¯

= 20.63, SD = 1.60) were asked to complete measures of mindfulness, wellbeing and anxiety before and after participating in an ‘intervention’. The intervention consisted of a mindfulness activity followed by either indoor bouldering (a form of rock-climbing) versus a physical activity control. A mixed ANOVA revealed that participation in bouldering increased the measure of mindfulness significantly more than the control activity; however, no significant group differences were found for the measures of wellbeing and anxiety. A regression analysis then revealed that group condition accounted for 33% of the variance in post-intervention mindfulness levels when controlling for baseline levels of mindfulness. This is the first study to experimentally demonstrate that engagement with rock-climbing increases mindfulness in young adults. Theoretically, the results have implications for our understanding of “flow” and optimal human experience. Practically, the study highlights the potential to implement rock-climbing as a resilience-building activity and integrate the sport within therapeutic frameworks.
Tensors with eigenvectors in a given subspace
Authors: Ottaviani Giorgio , Shahidi Zahra
Published: March 2021

The first author with B. Sturmfels studied in [16] the variety of matrices with eigenvectors in a given linear subspace, called the Kalman variety. We extend that study from matrices to symmetric tensors, proving in the tensor setting the irreducibility of the Kalman variety and computing its codimension and degree. Furthermore, we consider the Kalman variety of tensors having singular t-tuples with the first component in a given linear subspace and we prove analogous results, which are new even in the case of matrices. Main techniques come from Algebraic Geometry, using Chern classes for enumerative computations.
Historical and projected precipitation extremes over Pare watershed in Arunachal Pradesh, India
Authors: Singh W. R. , Barman S. , Sharma S. K. , Taggu A. , Bandyopadhyay A. , Bhadra A.
Published: March 2021

The aim of this paper is to understand the historical and future climate change situation using 15 extreme precipitation indices in the Pare watershed of Arunachal Pradesh, India. Historical period (1981–2019) and future period (2021–2050) precipitation data are used to compute extreme precipitation indices in RClimDex software. The Pare watershed was divided into 13 subwatersheds; however, the results of the study showed no significant spatial variation. This study found that majority of the precipitation extreme indices are showing decreasing trends during the historical period and most of them are statistically insignificant at 95% confidence level. Only three indices such as SDII, CWD and MRI are found significant at 0.05 level in the Pare watershed. Though not significant, the annual precipitation amount in the Pare watershed was found decreasing at the rate of 3.3 mm per year during the study period. The trend analysis over the whole watershed indicated significant decreasing trends for CWD and MRI while indicating significant increasing trend for SDII. The representative concentration pathway (RCP) 4.5 and 8.5 projected the extreme precipitation indices in a very similar way. The results of the trend analysis under RCP 8.5 showed significant decreasing trend only at SW10 for the index-moderate rainfall index (MRI). Various cases of RX1DAY and RX5DAY not falling during the months of monsoon were observed in both the historical and future periods. The percentage departures of the monsoon from its annual total had increased in RCP 4.5 and RCP 8.5 scenarios as compared to the historical periods. The results of this climatic investigation suggest that the precipitation regime in the study area had been accompanied and also expected by overall reduction in precipitation amount, milder rainfall events, reduction in monsoon (June–September) rainfall and drier climatic conditions. With the prevalent historical scenario and future projected scenarios of the extreme precipitation indices, the water resource potential in the study area is expected to be greatly reduced, for which the authors seek the attention of various stakeholders in water and allied sectors to come together and discuss on the construction of water conservation structures so that agricultural activities can be expanded and remain sustainable.
Demonstration of a Polymer-Based Single Step Waveguide by 3D Printing Digital Light Processing Technology for Isopropanol Alcohol-Concentration Sensor
Authors: Swargiary Kankan , Jolivot Romuald , Mohammed Waleed Soliman
Published: March 2021

A polymer based horizontal single step waveguide for the sensing of alcohol is developed and analyzed. The waveguide is fabricated by 3-dimensional (3D) printing digital light processing (DLP) technology using monocure 3D rapid ultraviolet (UV) clear resin with a refractive index of n = 1.50. The fabricated waveguide is a one-piece tower shaped ridge structure. It is designed to achieve the maximum light confinement at the core by reducing the effective refractive index around the cladding region. With the surface roughness generated from the 3D printing DLP technology, various waveguides with different gap sizes are printed. Comparison is done for the different gap waveguides to achieve the minimum feature gap size utilizing the light re-coupling principle and polymer swelling effect. This effect occurs due to the polymer-alcohol interaction that results in the diffusion of alcohol molecules inside the core of the waveguide, thus changing the waveguide from the leaky type (without alcohol) to the guided type (with alcohol). Using this principle, the analysis of alcohol concentration performing as a larger increase in the transmitted light intensity can be measured. In this work, the sensitivity of the system is also compared and analyzed for different waveguide gap sizes with different concentrations of isopropanol alcohol (IPA). A waveguide gap size of 300 µm gives the highest increase in the transmitted optical power of 65% when tested with 10 µL (500 ppm) concentration of IPA. Compared with all other gaps, it also displays faster response time (t = 5 seconds) for the optical power to change right after depositing IPA in the chamber. The measured limit of detection (LOD) achieved for 300 µm is 0.366 µL. In addition, the fabricated waveguide gap of 300 µm successfully demonstrates the sensing limit of IPA concentration below 400 ppm which is considered as an exposure limit by “National Institute for Occupational Safety and Health”. All the mechanical mount and the alignments are done by 3D printing fused deposition method (FDM).
Addressing the Disproportionate Impact of COVID-19 on Communities of Color
Authors: Graham Garth
Published: March 2021

With Black and Hispanic communities across the USA experiencing more detrimental negative effects from the COVID-19 pandemic as compared with other demographic groups, the virus has exposed the racial and ethnic disparities in treatment and care that public health experts have been grappling with for years. This paper explains how the systematic collection of racial and ethnic data gleaned from COVID-19 testing in underserved communities can be used to better understand this pandemic and inform measures within our control to prevent the spread of disease in the future.
Thermal kinetics of micro-defects in He-ion implanted W and W5Re alloys
Authors: Liu Yong-Li , Song Ya-Min , Li Lei , Bai Ruo-Yu , Zhang Peng , Zhang Qiao-Li , Jin Shuo-Xue , Zhu Te , Lu Er-Yang , Cao Xing-Zhong , Wang Bao-Yi
Published: March 2021

To investigate the thermal evolution of vacancy-type defects in He-ion irradiated W and W5Re alloy, different isochronal annealing treatments from 373 to 1273 K were conducted on the irradiated materials. Positron annihilation spectroscopy including positron annihilation lifetime spectroscopy and Doppler broadening spectroscopy were mainly used to characterize the micro-defects evolution. The results showed that the thermal evolution characteristics of defects in both W and W5Re were similar. After He-ion irradiation, mono-vacancies with positron annihilation lifetime of ~ 190 ps were detected in W, together with a large amount of dislocation loops with positron annihilation lifetime of ~ 150 ps in W5Re alloys. The coarsening of vacancy clusters at the expense of small vacancy clusters was the main thermal evolution feature of vacancy-type defects in both W and W5Re when annealing temperature increased to 1073 K. In this progress, the positron annihilation lifetime increased to ~ 350 ps (clusters composed of 4 –8 mono-vacancies) in both W and W5Re. As the temperature increased to 1273 K, the positron annihilation lifetime decreased to ~ 240 ps, which was attributed to a significant population reduction of the dislocation loops, the dissociation of large HenVm complexes and the annealing of micro-voids in both W and W5Re. The vacancy-type defects in W5Re were more susceptible to the annealing temperature because of the formation of vacancy cluster-Re complexes. Re clusters in irradiated W5Re alloy could serve as the nucleation sites of He bubbles, which promoted the swelling and protrusion formation on the surface.
Exergy Analysis for Energy Conversion Systems
Authors: Michaelides Efstathios
Published: March 2021

Discover a straightforward and holistic look at energy conversion and conservation processes using the exergy concept with this thorough text. Explains the fundamental energy conversion processes in numerous diverse systems, ranging from jet engines and nuclear reactors to human bodies. Provides examples for applications to practical energy conversion processes and systems that use our naturally occurring energy resources, such as fossil fuels, solar energy, wind, geothermal, and nuclear fuels. With more than one-hundred diverse cases and solved examples, readers will be able to perform optimizations for a cleaner environment, a sustainable energy future, and affordable energy generation. An essential tool for practicing scientists and engineers who work or do research in the area of energy and exergy, as well as graduate students and faculty in chemical engineering, mechanical engineering and physics.
Oil, Wine, and the Cultural Economy of Ancient Greece
Authors: Pratt Catherine E.
Published: March 2021

In this book, Catherine E. Pratt explores how oil and wine became increasingly entangled in Greek culture, from the Late Bronze Age to the Archaic period. Using ceramic, architectural, and archaeobotanical data, she argues that Bronze Age exchange practices initiated a strong network of dependency between oil and wine production, and the people who produced, exchanged, and used them. After the palatial collapse, these prehistoric connections intensified during the Iron Age and evolved into the large-scale industries of the Classical period. Pratt argues that oil and wine in pre-Classical Greece should be considered 'cultural commodities', products that become indispensable for proper social and economic exchanges well beyond economic advantage. Offering a detailed diachronic account of the changing roles of surplus oil and wine in the economies of pre-classical Greek societies, her book contributes to a broader understanding of the complex interconnections between agriculture, commerce, and culture in the ancient Mediterranean.
Play in the Early Years
Authors: Fleer Marilyn
Published: March 2021

Play is crucial to the learning and development of children in the early years. The third edition of Play in the Early Years is a comprehensive introduction to the theory and practice of play for children from birth to 8 years old. Drawing on classical and contemporary theories, this text examines social, cultural and institutional approaches to play, and explores a range of strategies for successfully integrating play into early years settings and primary classrooms. This edition features a new chapter on conceptual playworlds, which demonstrates what conceptual playworlds look like to infants and toddlers, pre-schoolers, and children transitioning into school. The text features classroom vignettes and photographs designed to help students connect theory to practice, and reflection questions and research activities encourage in-depth reflection and extend learning. Highly regarded by early childhood researchers and practitioners alike, Play in the Early Years remains an essential resource for pre-service students.
India and the World
Authors: Markovits Claude
Published: March 2021

In this pioneering history of modern India, Claude Markovits offers a new interpretation of events of world importance, focusing on the multiplicity of connections between India and the world. Beginning with an examination of India's evolving role in the world economy, he deals successively with the movement of people out of and into India, the role played by Indian soldiers in a series of conflicts from the mid-eighteenth to the late twentieth century, the place of India in the global circulation of ideas and cultural productions and the relationships established between Indians and others both abroad and at home. Challenging dominant state-centred histories by focusing on the lived experiences of people, Markovits demonstrates that the multiple connections established between India and other lands did not necessarily result in mutual knowledge, but were often marked by misunderstanding.
Policymaker perceptions of citizen needs: heuristics, accuracy, and partisan differences
Authors: BERGAN DANIEL E. , FITZPATRICK NATALIE
Published: March 2021

Do policymaker perceptions reflect actual citizen needs? A vast literature has explored the extent to which policy is responsive to public opinion, but there is little systematic work on policymaker perceptions of socialproblems. We quantify social problems with a unique dataset of the number of phone calls placed by citizens to a free service that connects Michigan residents to service providers. We combine these data with a survey of local policymakers’ perceptions of social problems facing their own city shows, consistent with theories of bounded rationality, that policymakers use heuristics to make judgments about the extent of constituent needs in their city, and that policymaker perceptions reflect the prevalence of needs. However, partisan perceptions of needs diverge, with Democrats consistently perceiving greater needs than Republicans. There is no evidence that policy activity on the needs in the sample is responsive to constituent needs. We conclude with implications for theories of policy making and avenues for future research.
Hayekian behavioral economics
Authors: Sunstein Cass R.
Published: March 2021

One of Friedrich Hayek's most important arguments pointed to the epistemic advantages of the price system, regarded as an institution. As Hayek showed, the price system incorporates the information held by numerous, dispersed people. Like John Stuart Mill, Hayek also offered an epistemic argument on behalf of freedom of choice. A contemporary challenge to that epistemic argument comes from behavioral economics, which has uncovered an assortment of reasons why choosers err, and also pointed to possible distortions in the price system. But, even if those findings are accepted, what should public institutions do? How should they proceed? A neo-Hayekian approach would seek to reduce the knowledge problem by asking what individual choosers actually do under epistemically favorable conditions. In practice, that question can be disciplined by asking five subsidiary questions: (1) What do consistent choosers, unaffected by self-evidently irrelevant factors, end up choosing? (2) What do informed choosers choose? (3) What do active choosers choose? (4) When people are free of behavioral biases, including (say) present bias or unrealistic optimism, what do they choose? (5) What do people choose when their viewscreen is broad, and they do not suffer from limited attention? These questions are illustrated with reference to the intense controversy over fuel economy standards.
Between the High Ideals and Reality: Managing COVID-19 Vaccine Nationalism
Authors: GRUSZCZYNSKI Lukasz , WU Chien-huei
Published: March 2021

This report examines what has come to be known as “vaccine nationalism” through the lens of the early experience with the COVID-19 vaccination process. After explaining the meaning of the term, this report investigates how this phenomenon has manifested during the COVID-19 pandemic, identifying its epidemiological, economical, ethical and legal aspects. It also looks at the different international initiatives that have been adopted to deal with it, concentrating in this context on the COVAX project. The report concludes that the success of these initiatives has been limited. It also observes that COVID-19 vaccine nationalism appears to be a phenomenon that is characteristic of the high-income Western countries, while in aspiring non-Western powers the vaccine crisis is primarily seen as a way to advance their geopolitical goals.
The incubatory chamber of marsupial carditids (Bivalvia: Carditidae: Thecaliinae) as an exaptation
Authors: Pérez Damián Eduardo , Soto Ignacio María
Published: March 2021

Marsupial carditids of the subfamily Thecaliinae are characterized by the presence of an “incubatory chamber” in female shells, where the eggs hatch and develop during their first stages. According to recent phylogenetic studies, Thecaliinae are closely related to Carditinae, a group that has a byssal gape. This structure occurs in the same area as the incubatory chamber, and both structures could be evolutionarily related. Using the newest phylogenetic context for the subfamilies, we test whether the incubatory chamber of Thecaliinae is related to characters present in Carditinae. We also provided a more precise definition of the implied structures. Two distinct morphologies for the incubatory chamber are described: one with an exteriorly opened pouch (present in the generaPowellinaandMilneria) and the other with a completely internal funicular infold (present inThecalia). The byssal gape is present in the Cardiobyssata clade (Carditamerinae + (Carditinae + Thecaliinae)), and we discuss whether the incubatory chamber could be the result of an exaptation event, and the possible evolutionary pathways implied. According to the present evidence, we propose a co-optation of the byssal gape into a new function (brooding of larvae) at some point during the transition from the Carditinae to the Thecaliinae lineages, thus determining an exaptation. Adaptative processes probably modified this structure into the incubatory chamber (an external pouch first, and a funicular infold later). We discuss alternative scenarios and implications on phylogenetic studies and the importance of considering non-adaptative evolutionary scenarios in the study of evolutionary narratives.
Managing the observatory: discipline, order and disorder at Greenwich, 1835–1933
Authors: Johnston Scott Alan
Published: March 2021

This article presents a case study of life and work at the Royal Observatory at Greenwich (1835–1933) which reveals tensions between the lived reality of the observatory as a social space, and the attempts to create order, maintain discipline and project an image of authority in order to ensure the observatory's long-term stability. Domestic, social and scientific activities all intermingled within the observatory walls in ways which were occasionally disorderly. But life at Greenwich was carefully managed to stave off such disorder and to maintain an appearance of respectability which was essential to the observatory's reputation and output. The article focuses on three areas of management: (1) the observatory's outer boundaries, demonstrating how Greenwich navigated both human and environmental intrusions from the wider world; (2) the house, examining how Greenwich's domestic spaces provided stability, while also complicating observatory life via the management of domestic servants; and (3) the scientific spaces, with an emphasis on the work and play of the observatory's boy computers. Together, these three parts demonstrate that the stability of the observatory was insecure, despite being perpetuated via powerful physical and social boundaries. It had to be continually maintained, and was regularly challenged by Greenwich's occupants and neighbours.
Answering for the past: Exploring the conditions of answerability over time
Authors: Ramsoomair Nicole
Published: March 2021

Whether seen after a vehement denunciation of one's former values or a subtle change of heart, it is often thought that significant change to one's evaluative character could undermine responsibility for past wrongdoing. In this article, I explore this intuition by analyzing Angela Smith's concept of “responsibility as answerability.” I introduce an alteration/replacement distinction to define the limits of answerability over time. These limits are then further qualified by drawing on Delia Graff's work on Sorites type cases to argue that persons are answerable for past wrongdoing if they remain “saliently similar” in some relevant respects
Weak recovery of epiphytic lichen communities in Sweden over 20 years of rapid air pollution decline
Authors: Weldon James , Grandin Ulf
Published: March 2021

Epiphytic lichens are sensitive to deteriorating air quality, but levels of nitrogen and especially sulphur deposition have been in decline over most of Europe in recent decades. We assessed the response of epiphytic lichens to this decline, using data from long-term monitoring sites in Sweden. We analyzed 20 years of data to investigate temporal trends in lichen communities’ sensitivity to sulphur, nitrogen preference, species richness and alpha and beta diversity. We found only limited and partial evidence of recovery in the area that previously had high levels of deposition, and a decline in mean sulphur sensitivity at a northern site with low deposition levels throughout the monitoring period. The slow recolonization of sensitive species, even where environmental conditions are now suitable, is probably a result of impoverished regional species pools and the inherent limited dispersal capacity of many lichen species. We suggest due consideration of these factors in the use of epiphytic lichens as environmental indicators in a period of improving air quality.
The independent and combined effects of cannabis use and systemic inflammation during the early stages of psychosis: exploring the two-hit hypothesis
Authors: Corsi-Zuelli Fabiana , Marques Leonardo , da Roza Daiane Leite , Loureiro Camila Marcelino , Shuhama Rosana , Di Forti Marta , Menezes Paulo Rossi , Louzada-Junior Paulo , Del-Ben Cristina Marta
Published: March 2021

Background

Cannabis consumption is a modifiable risk factor associated with psychosis, but not all cannabis users develop psychosis. Animal studies suggest that an antecedent active immune system interacts with subsequent cannabis exposure and moderates the cannabis–psychosis association, supporting the two-hit hypothesis. The clinical investigations are few, and it is unclear if the immune system is a biological candidate moderating the cannabis–psychosis association or whether cannabis increases inflammation, which in turn, augments psychosis likelihood.

Methods

We explored the mediating and moderating role of blood inflammation using PROCESS macro. We used data from a cross-sectional study, including 153 first-episode psychosis patients and 256 community-based controls. Participants answered the Cannabis Experience Questionnaire (cannabis frequency, age of onset, and duration), and plasma cytokines were measured [interleukin (IL)-1β, IL-6, IL-4, IL-10, tumour necrosis factor-α (TNF-α), interferon-γ (IFN-γ), transforming growth factor-β (TGF-β); multiplex]. We computed an inflammatory composite score (ICS) to represent the systemic inflammatory state. Confounders included sex, age, ethnicity, educational level, body mass index, tobacco smoking, lifetime use of other drugs, and antipsychotic treatment.

Results

Mediation: Cannabis consumption was not associated with increased inflammation, thus not supporting a mediating effect of inflammation. Moderation: Daily use and age of onset <17 interacted significantly with the ICS to increase the odds of psychosis beyond their individual effects and were only associated with psychosis among those scoring medium–high in the ICS.

Conclusions

Immune dysregulation might be part of the pathophysiology of psychosis, not explained by cannabis use or other confounders. We provide the first and initial evidence that immune dysregulation modifies the cannabis–psychosis association, in line with a two-hit hypothesis.
An Ethiopian Scholar in Tridentine Rome: Täsfa Ṣeyon and the Birth of Orientalism
Authors: Salvadore Matteo , De Lorenzi James
Published: March 2021

This article surveys the diasporic life and legacy of the Ethiopian ecclesiastic Täsfa Ṣeyon. After examining his origins in the Christian kingdom of Ethiopia and the circumstances of his arrival in mid-sixteenth-century Rome, the article outlines his contributions to the evolving Latin Catholic understanding of Ethiopia. Täsfa Ṣeyon was a librarian, copyist, teacher, translator, author, and community leader, as well as a prominent adviser to European humanist scholars and Church authorities concerned with orientalistphilologia sacraas it pertained to Ethiopian Orthodox (täwaḥedo) Christianity. As such, he was a key extra-European agent in the Tridentine project of Ethiopianist and Eastern Christian knowledge production. The article also surveys the complex modern legacy of Täsfa Ṣeyon's career, documenting his posthumous influence in the fields of Ethiopianist Semitic studies and Ethiopian vernacular historiography.
The Ugandan hip-hop image: the uses of activism and excess in fragile sites
Authors: Singh Simran
Published: March 2021

This article discusses the characteristics of image in Ugandan hip-hop with a particular focus on representations of activism and excess. Locating Uganda as a fragile site on the basis of widespread political, social and economic marginalisation, this examination considers members of Uganda's first generation of hip-hop artists, to argue that both activism and excess act in singular response to these circumstances. Finding articulation in strivings for economic freedom and social justice, the Ugandan hip-hop image reveals negotiations of histories of colonialism and of contemporary neoliberal capitalism: in doing so, it raises intersections of race and gender, informed by hip-hop's significance as a multi-billion-dollar global industry. This cross-disciplinary inquiry combines ethnomusicology with media, cultural and visual studies in dialogue with political economy.
‘I say high, you say low’: the Beatles and cultural hierarchies in 1960s and 1970s Britain
Authors: Collins Marcus
Published: March 2021

The debate over the cultural value of the Beatles was as vehement as it was significant in 1960s and early 1970s Britain. Lennon and McCartney's early compositions received some early critical plaudits,Sgt. Peppersought to blur distinctions between high and low culture and the band members’ side projects forged links with the avant garde. To accept the Beatles as artists, however, required critics to rethink how art was created, disseminated and evaluated and how it interacted with contemporary social, economic and technological change. This article makes extensive use of contemporary journalism, scholarship and fan literature, much of it unstudied, to demonstrate that the rethinking process was contested and protracted. No consensus emerged. Claims made for their artistry, which contributed to a wider discourse elevating ‘rock’ over ‘pop’, were countered by cultural conservatives who defended their own status as artists and intellectuals by exposing the Beatles as kitsch.
Claire Kramsch in conversation with Zhu Hua
Authors: Kramsch Claire , Hua Zhu
Published: March 2021

The following conversation between Zhu Hua (ZH) and Claire Kramsch (CK) was conducted on 27 October 2020 at a webinar organized by Rebecca Taylor and Rachel Tonkin from Cambridge University Press on the occasion of the impending publication of Claire's book Language as Symbolic Power and in the shadow of the imminent presidential American election. What follows are extracts from the conversation in which we have incorporated some of the questions sent in by the attendees.ZH:

What motivated you to choose this topic for your book?
Physical parameters of bovine activated oocytes and zygotes as predictors of development success
Authors: Timlin Claire L. , Lynn Alexa , Wooldridge Lydia K. , Uh Kyungjun , Ealy Alan D. , White Robin R. , Lee Kiho , Mercadante Vitor R.G.
Published: March 2021

The worldwide production of in vitro-produced embryos in livestock species continues to grow. The current gold standard for selecting quality oocytes and embryos is morphologic assessment, yet this method is subjective and varies based on experience. There is a need for a non-invasive, objective method of selecting viable oocytes and embryos. The aim of this study was to determine if ooplasm area, diameter including zona pellucida (ZP), and ZP thickness of artificially activated oocytes and in vitro fertilized (IVF) zygotes are indicative of development success in vitro and correlated with embryo quality, as assessed by total blastomere number. Diameter affected the probability of development to the blastocyst stage in activated oocytes on day 7 (P < 0.01) and day 8 (P < 0.001), and had a tendency to affect IVF zygotes on day 8 (P = 0.08). Zona pellucida thickness affected the probability of development on day 7 (P < 0.01) and day 8 (P < 0.001) in activated oocytes, and day 8 for IVF zygotes (P < 0.05). An interaction between ZP thickness and diameter was observed on days 7 and 8 (P < 0.05) in IVF zygotes. Area did not significantly affect the probability of development, but was positively correlated with blastomere number on day 8 for IVF zygotes (P = 0.01, conditional R2 = 0.09). Physical parameters of bovine zygotes have the potential for use as a non-invasive, objective selection method. Upon further development, methods used in this study could be integrated into embryo production systems to improve IVF success.
The Michigan Appropriateness Guide for Intravenous Catheters in children with congenital heart disease: miniMAGIC-CHD
Authors: Perry Tanya , Ullman Amanda J , Aiyagari Ranjit , Pitts Stephanie , Jacobs Jeffrey P , Cooper David S
Published: March 2021

Background:

The approach to vascular access in children with CHD is a complex decision-making process that may have long-term implications. To date, evidence-based recommendations have not been established to inform this process.

Methods:

The RAND/UCLA Appropriateness Method was used to develop miniMAGIC, including sequential phases: definition of scope and key terms; information synthesis and literature review; expert multidisciplinary panel selection and engagement; case scenario development; and appropriateness ratings by expert panel via two rounds. Specific recommendations were made for children with CHD.

Results:

Recommendations were established for the appropriateness of the selection, characteristics, and insertion technique of intravenous catheters in children with CHD with both univentricular and biventricular physiology.

Conclusion:

miniMAGIC-CHD provides evidence-based criteria for intravenous catheter selection for children with CHD.
RECIPROCITY SHEAVES AND THEIR RAMIFICATION FILTRATIONS
Authors: Rülling Kay , Saito Shuji
Published: March 2021

We define a motivic conductor for any presheaf with transfersFusing the categorical framework developed for the theory of motives with modulus by Kahn, Miyazaki, Saito and Yamazaki. IfFis a reciprocity sheaf, this conductor yields an increasing and exhaustive filtration on$F(L)$, whereLis any henselian discrete valuation field of geometric type over the perfect ground field. We show that ifFis a smooth group scheme, then the motivic conductor extends the Rosenlicht–Serre conductor; ifFassigns toXthe group of finite characters on the abelianised étale fundamental group ofX, then the motivic conductor agrees with the Artin conductor defined by Kato and Matsuda; and ifFassigns toXthe group of integrable rank$1$connections (in characteristic$0$), then it agrees with the irregularity. We also show that this machinery gives rise to a conductor for torsors under finite flat group schemes over the base field, which we believe to be new. We introduce a general notion of conductors on presheaves with transfers and show that on a reciprocity sheaf, the motivic conductor is minimal and any conductor which is defined only for henselian discrete valuation fields of geometric type withperfectresidue field can be uniquely extended to all such fields without any restriction on the residue field. For example, the Kato–Matsuda Artin conductor is characterised as the canonical extension of the classical Artin conductor defined in the case of a perfect residue field.