bluuebunny/crossref_metadata_2025 huggingface dataset:
Career Women’s Perception of Social Attractiveness and Appearance Management Behavior
Authors: Lee Goeun , Lee Yoon-Jung , Lee Minsun , Hwang Jung-Sun
Published: February 2023

This study focused on working women’s perceptions of social attractiveness and their appearance management behavior. Social attractiveness is defined as individuals’ achieved attractiveness which can be expressed through social expressive power or social skills rather than innate physical appearance. This study was empirically conducted through questionnaires distributed to 200 working women in South Korea. According to the results, the participants recognized four factors constituting social attractiveness: physical appearance management, business manners, social skills, and sexual attractiveness. When they were asked to assess themselves on the same measures, these characteristics were further classified into six factors: business manners, feminine attractiveness, fashion sense, sociability, communication skills, and active appearance management. Their self-perceived social attractiveness was found to be influenced by all these factors in the order of feminine attractiveness, business manners, sociability, communication skills. Based on the self-presentation tendencies, the participants were classified into various groups, including the passive management group, daily life-oriented management group, work-oriented management group, neutral group, and active management group. The relative importance of the social attractiveness components was found to differ by group, although working women in all groups rated weight management higher than appearance management behavior. This study has implications in that it facilitates an understanding of the concept of social attractiveness and also provides a foundation base in terms of beauty consulting and marketing for working women to improve their social attractiveness.
WhoseEgg: classification software for invasive carp eggs
Authors: Goode Katherine , Weber Michael J. , Dixon Philip M.
Published: February 2023

The collection of fish eggs is a commonly used technique for monitoring invasive carp. Genetic identification is the most trusted method for identifying fish eggs but is expensive and slow. Recent work suggests random forest models could provide an inexpensive method for identifying invasive carp eggs based on morphometric egg characteristics. While random forests provide accurate predictions, they do not produce a simple formula for obtaining new predictions. Instead, individuals must have knowledge of the R coding language, limiting the individuals who can use the random forests for resource management. We present WhoseEgg: a web-based point-and-click application that allows non-R users to access random forests via a point and click interface to rapidly identify fish eggs with an objective of detecting invasive carp (Bighead, Grass, and Silver Carp) in the Upper Mississippi River basin. This article provides an overview of WhoseEgg, an example application, and future research directions.
The prognostic and clinicopathological significance of SLC7A11 in human cancers: a systematic review and meta-analysis
Authors: Wang Jiantao , Hao Siyuan , Song Guojiao , Wang Yan , Hao Qiukui
Published: February 2023

Objective

It is of great importance to recognize bio-markers for cancer prognosis. However, the association between solute carrier family 7 member 11 (SLC7A11) and prognosis is still controversial. Therefore, we conducted this systematic review and meta-analysis to identify the prognostic and clinicopathological significance of SLC7A11 in human cancers.

Methods

PubMed, Web of Science, Scopus, the Cochrane Library and Embase database were searched from database inceptions to March 19th 2022. Hand searches were also conducted in references. Prognosis and clinicopathological data were extracted and analyzed.

Results

A total of 12 eligible studies with 1,955 patients were included. The results indicated that SLC7A11 expression is associated with unfavorable overall survival (OS), unfavorable recurrence-free survival (RFS) and unfavorable progression free survival (PFS). And SLC7A11 expression is also associated with more advanced tumor stage.

Conclusions

SLC7A11 expression is associated with more unfavorable prognosis and more advanced tumor stage. Therefore, SLC7A11 could be a potential biomarker for human cancer prognosis.
Differential lncRNA/mRNA expression profiling and ceRNA network analyses in amniotic fluid from foetuses with ventricular septal defects
Authors: Wang Huaming , Lin Xi , Wang Zecheng , He Shaozheng , Dong Bingtian , Lyu Guorong
Published: February 2023

Background

Long noncoding RNAs (lncRNAs) have been shown to be involved in the regulation of numerous biological processes in embryonic development. We aimed to explore lncRNA expression profiles in ventricular septal defects (VSDs) and reveal their potential roles in heart development.

Methods

Microarray analyses were performed to screen differentially expressed lncRNAs (DE-lncRNAs) and mRNAs (DE-mRNAs) in the amniotic fluid between the VSD group and the control group. Bioinformatics analyses were further used to identify the functional enrichment and signaling pathways of important mRNAs. Then, a coding–noncoding gene coexpression (CNC) network and competitive endogenous RNAs (ceRNA) network were drawn. Finally, qRT‒PCR was performed to verify several hub lncRNAs and mRNAs in the network.

Results

A total of 710 DE-lncRNAs and 397 DE-mRNAs were identified in the VSD group. GO and KEGG analyses revealed that the DE-mRNAs were enriched in cardiac development-related biological processes and pathways, including cell proliferation, cell apoptosis, and the Sonic Hedgehog signaling pathway. Four VSD related mRNAs was used to construct the CNC network, which included 149 pairs of coexpressing lncRNAs and mRNAs. In addition, a ceRNA network, including 15 lncRNAs, 194 miRNAs, and four mRNAs, was constructed to reveal the potential regulatory relationship between lncRNAs and protein-coding genes. Finally, seven RNAs in the ceRNA network were validated, including IDS, NR2F2, GPC3, LINC00598, GATA3-AS1, PWRN1, and LINC01551.

Conclusion

Our study identified some lncRNAs and mRNAs may be potential biomarkers and therapeutic targets for foetuses with VSD, and described the lncRNA-associated ceRNA network in the progression of VSD.
A Two-stream Convolutional Neural Network-based Pornography Recognition Method
Authors: He Congcong , Huang Qinglin , Luo Jieyuan
Published: February 2023

The main approach taken to identify pornographic video content is achieved by performing pornography detection on the video content. By extracting features from video key frames and using some common neural network models to recognize the extracted key frame images, a certain accuracy rate can be obtained. However, another key information of video recognition, action information, is ignored, which leads to misclassification of some indistinguishable videos such as sumo wrestling and boxing. A dual-stream convolutional neural network-based pornographic video recognition method is proposed to address this problem. The experimental results show that the dual-stream convolutional neural network effectively improves the recognition rate of indistinguishable pornographic videos.
Knowledge of Nurses, Attitudes and Practices Related to Blood Transfusion at the Neonatal and Pediatric Intensive Care Unit at University Hospital Mohammed VI Marrakech Morocco
Authors: Tahiri F. , Lalaoui A. , Bennaoui F. , Slitine N. El Idrissi , Younous S. , Maoulainine F. M. R.
Published: February 2023

Blood transfusion is a therapeutic substitute, saving millions of lives each year.

This practice is common at the neonatal and pediatric intensive care levels.

In order to ensure transfusion safety, control of all stages of the transfusion chain is essential from the collection of blood, its preparation and its biological qualification to the completion of the transfusion procedure and even the follow-up of recipients.

With this in mind, the purpose of this study is to describe the state of knowledge of nursing practice in the area of blood transfusion at the level of neonatal and pediatric intensive care unit at Mohammed VI University Hospital in Marrakech, based on a descriptive approach guided by a frame of reference from the literature review.

We collected our results based on an annotated questionnaire, we found that nurses who had already received specialized training in transfusion rules had a satisfactory level of knowledge compared to those who had not received any training For this we recommend through our survey the importance of continuing training of nursing staff.
A Study of Perception and Acceptance of COVID 19 Vaccination by Pregnant Women in a Tertiary Health Centre in Delhi, India
Authors: Fatima Faeza , Khan Muntaha , Puri Manju , Chaudhary Kamran
Published: February 2023

The pandemic has led to a major change of focus in the healthcare system. The pandemic that started in December 2019 in Wuhan rapidly became a global health crisis. Pregnant women fall under the high risk category and the infection endangers two lives. Vaccination appeared as the only hope at the peak of pandemic.

Materials and Methods: 650 pregnant women at a tertiary care centre in New Delhi were interviewed objectively irrespective of gestational age and educational status.

Results and Discussion: 383 women(58.9%) pregnant women were willing to get the vaccine. 267 (41.1%) were not willing to the get the vaccine. 91.5 % women were aware that covid-19 vaccine is available for pregnant women. 90.3% women knew that covid 19 infection can be dangerous for pregnant women. Only 75.7 % women thought covid 19 infection can be dangerous for new born and children. Women who were aware that the infection can be dangerous for pregnant women and newborn were more willing to get the vaccine compared to women who were not aware. Women who thought the vaccine could be harmful for the fetus were reluctant to get the vaccine.

Conclusion: Increasing awareness and knowledge in the pregnant population would lead to better vaccine acceptability. Vaccination status among pregnant population is still poor and with better awareness drives we can improve the vaccination statistics. The results can be extrapolated for other health drives and health seeking behavior development.
Effect of Different Organic Manures and Varieties on Growth Parameter of Sprouting Broccoli (Brassica oleracea var. Italica plenck)
Authors: Kumar Mukesh , Lata Rubee , Verma Subhash , Kumar Shani , Kishor Braj , Veersain . , Sangam Surabhi
Published: February 2023

Studies on the effect of different organic sources (soil, FYM, cocopeat, vermicompost, neem cake, and poultry manure) and varieties (V2 Pusa KTS-1 and V1 Green Head) on different growth attributes in sprouting broccoli (Brassica oleracea var. italica Plenck). Experiment was carried out in a randomized block design with three replications at the Department of Horticulture, Babasaheb Bhimrao Ambedkar University Lucknow, 226025 (U P), India, during the Rabi season of 2019-2020. We examined different growth parameters such as Plant height, Number of leaves per plant, Stem diameter (mm), Plant spread east-west (cm), Plant spread north-south (cm), Length of leaves, and Width of leaves. We found that growth parameter are highly effected by vermicompost over the poultry manure, while minimums were reported for S (soil) or control, as well as Neemcake, FYM, and cocopeat at all stages. Hence, organic manure (vermicompost) had the highest effects on growth attributes. We found that variety V2 (Pusa KTS-1) has a significantly greater effect on vermicopost than variety V1 (Green Head).
Effect of Pre-sowing Seed Treatments and Synthetic Polymer Coating on Seed Quality and Storability in Redgram (Cajanus cajan. L.)
Authors: Swarnalatha V. , Parimala K. , Prabhavathi K. , Pradeep T.
Published: February 2023

Successful agriculture depends on high-quality seed, which is a fundamental and important ingredient. Under unfavourable environmental conditions like drought, pre-sowing seed treatment such as seed coating and seed priming could boost the seed germination and seedling vigour. The coating agents often include plant growth regulators, micro-fertilizers, pesticides, and insecticides. The present investigation was carried out to assess the impact of seed treatment and polymer coating on seed quality parameters of pigeon pea cv PRG 176 during 2018 to 2021 at Seed Research and Technology Centre, Rajendranagar, Hyderabad. The trail was laid out in randomized block design with four replications. Freshly harvested redgram variety Ujwala Seeds were treated for Seed hardening with ZnSO4 @100ppm + Seed coating with Polymer 3ml/kg + Bavistin 2g/kg + Imidacloprid 1ml/kg + Pseudomonas fluorescens 10 g/kg + Rhizobium in different combinations. The treated seeds were shade dried, packed in gunny bags, and stored at room temperature to assess the impact of various treatments on seed quality metrics under ambient storage conditions. The results of bimonthly observations on seed quality parameters showed that there were substantial differences between the treatments for the characters under study. The T7 treatment recorded highest germination percentage (98 and 70.67), speed of emergence (12.1 and 10.1), electrical conductivity (0.169 and 0.292), seedling shoot length (14.9 and 8.65cm), seedling root length (14.5 and 8.52cm), seedling length (29.4 and 17.17cm), seedling fresh weight (5.55 and 2.5g), seedling dry weight (0.40 and 0.21g), seed vigour index-I (2881 and 1213), seed Vigour Index-II (53.9 and 14.84) over other treatments under study at initiation of studies (2MAS) and at 28 months of storage period respectively. The current study's findings showed that T7 treatment greatly outperformed all other treatments for all characters, maintaining an optimal germination percentage (70.67%) even up to 28 months of storage under ambient storage conditions.
Effect of Vermicompost and Organic Formulations on Yield and Quality of Soybean Grown on Vertisol
Authors: Lokhande P. B. , Dhamak A. L. , Todmal S. M. , Patil N. M.
Published: February 2023

The field experiments were conducted during kharif-2020 and kharif-2021 at Research Farm, Department of Soil Science and Agril. Chemistry, College of Agriculture, VNMKV Parbhani, to study the effect of vermicompost and organic formulations on yield and quality of soybean grown on Vertisol. The experiment was laid in factorial randomized block design with twelve treatments and three replications. Experimental treatments consist of two factors in which one factor consist of vermicompost consist of three levels C1-RDF, C2- Vermicompost eq. to RDN, C3- Vermicompost eq. to RDN + RD of vermicompost @ 5 t ha-1, another factor organic formulations consist of four levels OF0- control, OF1- Pancahgavya, OF2- Beejamruth + Jeevamruth, OF3-Beejamruth + Jeevamruth + Pancahgavya. The yield parameters like no. of pods, seed and straw yield and quality parameters like protein content and test weight showed significant increased with the application of RDF as compared to other treatments. Among organic formulations treatments highest value was recorded in combined application of Beejamruth + Jeevamruth + Pancahgavya (OF3) as compared to alone application. The significant increase in seed and straw yield was recorded in treatment receiving RDF (C1) along with combined application of Beejamruth + Jeevamruth + Pancahgavya (OF3). The result of the experiment revealed that application of RDF along with combined application of Beejamruth + Jeevamruth + Pancahgavya was found beneficial for increase in yield and quality of soybean grown in Vertisol.
Incorporation of Glass from Used Photovoltaic Solar Modules into the Concrete Matrix of Construction as a Partial Replacement of Cement in Burkina Faso
Authors: Ouiminga Abdoul Aziz , Kaboré Boureima , Ouedraogo Germain Wende Pouiré , Kam Sié
Published: February 2023

Several wastes can be recycled and used in the field of civil engineering. The incorporation of glass waste into the concrete matrix allows us to sustain and preserve natural resources. The aim of this study is to efficiently recycle glass waste from photovoltaic solar modules, for use in concrete as a partial replacement for cement. We obtained in this work different results depending on the amount of glass added to replace the cement. The tests began on the 7th day of concrete production and we waited until the twenty-eighth of concrete production, which is 10/29/2022, for the final compressions to be carried out. The control concrete P1 gives a value of 23.88MPa or 95.52% of 25MPa, the glass-enhanced concrete 10% of the weight of cement P2 presents a value of 24.66MPa or 99.04% of 25MPa, for the glass-enhanced concrete 15% of the weight of P3 cement we obtain 20.36MPa or 81.44% of 25MPa, Glass-enhanced concrete 20% of the weight of P4 cement gives a value of 17.88MPa or 71.52% of 25 MPA. P2 presents a higher result than that of the control concrete (24.66MPa > 19.49 MPa). We also note that the value of P2 is very close to the normal fixed during the formulation of the concrete. Therefore, we can say that the compression result of the 28th day of the improved concrete of the glass 10% of the P2 cement is acceptable compared to the others (P1, P3, P4). As the PV solar module has several components such as resin, Tedlar, solar cells and aluminum, it is not excluded to make a hypothesis on the chemical impact of these in the glass powder. This requires full-fledged research on the properties of used glass in order to improve the values of the compressive strength and to draw a conclusion on the incorporation of glass into the concrete matrix in Burkina Faso. The use of waste glass in              concrete will contribute to sustainable development. The incorporation of glass waste into the concrete matrix allows us to reduce associated carbon dioxide emissions and lower cement production costs.
Born in ’47
Authors: Sandle Rod
Published: February 2023

Just like a personal ego, the zeitgeist of a practice such as psychotherapy is constantly changing, influenced by both internal and external events. As with the personal ego, not only is it changing but it is also resisting change, leading to a state of imbalance and potential conflict. A psychotherapeutic relationship can help an individual re-establish balance in the changing world and live more fully in the present, but the relationship with an organisation or group can be more challenging. Just as we can identify with our ego, so can we identify with a group: does the onus fall more on the individual or the group to adapt, both to change and to the resistance to change? What can help in this process of adaptation? With the Freudian concept of the erotic bonds of love and hate in the background, I will call on my personal story as a psychotherapist born in the year the New Zealand Association of Psychotherapists (NZAP) was founded, with the aim of exploring these questions with a focus on the changing zeitgeist of NZAP.
Opportunities and challenges for psychotherapy in Aotearoa New Zealand’s new health system
Authors: Whisker Craig
Published: February 2023

The dawning of a new national public health system in Aotearoa New Zealand offers opportunities and challenges for psychotherapists. This paper discusses these against three data sets, namely, a 2022 national District Health Board psychotherapy workforce survey, a video recording of the Psychotherapy and Public Worlds panel event at the 2022 New Zealand Association of Psychotherapists’ (NZAP) conference, and psychotherapist registration statistics supplied by The Psychotherapists Board of Aotearoa New Zealand (PBANZ). The expansion of short-term, risk-based, manualised interventions during the former DHB era did not improve mental health at a community level (Mulder et al., 2022) nor promote equity and sustainability (Berg et al., 2022). Placing Te Tiriti o Waitangi, the Treaty of Waitangi (1840) (Te Tiriti) at the centre of the new health system suits psychotherapy, whose wholistic worldview of health and wellbeing aligns with te ao Māori better than most other Western psychological approaches. Kōrero about the indigenising of psychotherapy in Aotearoa has been around since at least the 1980s. The Ministry of Health (the Ministry) has recently invited psychotherapists’ advice on workforce policy development and how to promote psychotherapy in the new health system. This task will largely fall on the psychotherapy associations and some psychotherapy training organisations. A major challenge may be whether these entities can sustain the expenditure of human and other resources necessary to represent their memberships in continuing dialogue with the Ministry and its operational partners, Te Whatu Ora, Health New Zealand (Te Whatu Ora) and Te Aka Whai Ora, Māori Health Authority (Te Aka Whai Ora). Key opportunities include the recruitment of overseas psychotherapists and the greatly expanded provision of psychotherapy student placements in public health services to stimulate new psychotherapy training programmes and workforce growth.
Notes on notes
Authors: Tudor Keith , Gledhill Kris
Published: February 2023

This article offers information and views about note-taking and record-keeping in the practice of psychotherapy in this country, in the context of the limited literature on the topic. It provides a brief review of what principal figures wrote about taking notes and making records, specifically Sigmund Freud and Eric Berne. It considers the purpose of making notes and keeping records, and presents key terms and conditions on the subject. Finally, it reviews relevant declarations and legislation regarding notes and records pertinent to the practice of psychotherapy in Aotearoa New Zealand.
Between the Harbour and the Mountain: Reflections on the Ordinary and the Profound
Authors: O'Connor John
Published: February 2023

In this beautifully written and elegantly presented book the author, Patricia Williams, offers us her contemplations on the everyday world she encounters, with particular attention to the natural world and its ordinary and wondrous manifestations. Whilst many of us in today’s technological age allow our attention to be distracted from the intimate detail of the natural world that enables life on this planet, Williams invites us to notice the extraordinary and sometimes frightening detail of this world within which we are all embedded, indeed intimately interconnected, as she brings her piercingly attentive gaze to the everyday. In doing so Williams reflects upon the meaning she has drawn from her rich and courageous life, allowing us not only to encounter the natural world through her eyes, but also to enter into the mind of a woman, now formally retired, who has spent her life reflecting upon and engaging with the deep questions of meaning with which we all might grapple, should we have the courage to do so.
Evaluation of Carbon Emissions According to the Steep Slope Maintenance Project
Authors: Joo Jingul , Lee Jungmin , Park Moojong
Published: February 2023

Reducing carbon emissions due to climate change has emerged as a national objective. To achieve carbon-free emissions nationally by 2050, evaluating and reducing carbon emissions is essential for efficient disaster management. In this study, a method for quantitatively evaluating carbon emissions in disaster management projects was proposed. Disaster management projects were divided into detailed processes, and in each process, the extent of equipment operation and amount of raw material used for unit construction work were presented using standard production of construction work. The carbon emissions resulting from equipment operation and material usage were based on the standards given by the Ministry of Land, Infrastructure, and Transport. Finnally, amount of carbon emissions for unit construction volume during each detailed process were estimated. Using developed methods, carbon emissions were calculated at the steep slope maintenance project. The results indicated that 89.4% of the total carbon emissions were generated from pouring concrete, such as cement and ready-mixed concrete. Thus, reduction of cement and concrete usage is essential for reducing carbon emissions in disaster management projects.
Race-Based Equations Delayed Black Patients From Getting Onto Kidney Transplant Lists—An Unprecedented New Policy Seeks to Undo the Damage
Authors: Abbasi Jennifer
Published: February 2023

This Medical News article is an interview about new policy from the US Organ Procurement and Transplantation Network to address the harms of race-based kidney function estimation.
Holding Medical Professional Society Scientific Meetings Only in States That Protect Abortion Rights—Clinical and Ethical Considerations
Authors: Gross Cary P. , Kraschel Katherine L. , Emanuel Ezekiel J.
Published: February 2023

This Viewpoint suggests that professional societies should continue to advocate for equitable access for patients to all necessary medical care including abortion care.
Integrating Alcohol-Related Prevention and Treatment Into Primary Care
Authors: Lee Amy K. , Bobb Jennifer F. , Richards Julie E. , Achtmeyer Carol E. , Ludman Evette , Oliver Malia , Caldeiro Ryan M. , Parrish Rebecca , Lozano Paula M. , Lapham Gwen T. , Williams Emily C. , Glass Joseph E. , Bradley Katharine A.
Published: February 2023

Importance

Unhealthy alcohol use is common and affects morbidity and mortality but is often neglected in medical settings, despite guidelines for both prevention and treatment.

Objective

To test an implementation intervention to increase (1) population-based alcohol-related prevention with brief interventions and (2) treatment of alcohol use disorder (AUD) in primary care implemented with a broader program of behavioral health integration.

Design, Setting, and Participants

The Sustained Patient-Centered Alcohol-Related Care (SPARC) trial was a stepped-wedge cluster randomized implementation trial, including 22 primary care practices in an integrated health system in Washington state. Participants consisted of all adult patients (aged ≥18 years) with primary care visits from January 2015 to July 2018. Data were analyzed from August 2018 to March 2021.

Interventions

The implementation intervention included 3 strategies: practice facilitation; electronic health record decision support; and performance feedback. Practices were randomly assigned launch dates, which placed them in 1 of 7 waves and defined the start of the practice’s intervention period.

Main Outcomes and Measures

Coprimary outcomes for prevention and AUD treatment were (1) the proportion of patients who had unhealthy alcohol use and brief intervention documented in the electronic health record (brief intervention) for prevention and (2) the proportion of patients who had newly diagnosed AUD and engaged in AUD treatment (AUD treatment engagement). Analyses compared monthly rates of primary and intermediate outcomes (eg, screening, diagnosis, treatment initiation) among all patients who visited primary care during usual care and intervention periods using mixed-effects regression.

Results

A total of 333 596 patients visited primary care (mean [SD] age, 48 [18] years; 193 583 [58%] female; 234 764 [70%] White individuals). The proportion with brief intervention was higher during SPARC intervention than usual care periods (57 vs 11 per 10 000 patients per month; P < .001). The proportion with AUD treatment engagement did not differ during intervention and usual care (1.4 vs 1.8 per 10 000 patients; P = .30). The intervention increased intermediate outcomes: screening (83.2% vs 20.8%; P < .001), new AUD diagnosis (33.8 vs 28.8 per 10 000; P = .003), and treatment initiation (7.8 vs 6.2 per 10 000; P = .04).

Conclusions and Relevance

In this stepped-wedge cluster randomized implementation trial, the SPARC intervention resulted in modest increases in prevention (brief intervention) but not AUD treatment engagement in primary care, despite important increases in screening, new diagnoses, and treatment initiation.

Trial Registration

ClinicalTrials.gov Identifier: NCT02675777
Prevalence, Timing, and Network Localization of Emergent Visual Creativity in Frontotemporal Dementia
Authors: Friedberg Adit , Pasquini Lorenzo , Diggs Ryan , Glaubitz Erika A. , Lopez Lucia , Illán-Gala Ignacio , Iaccarino Leonardo , La Joie Renaud , Mundada Nidhi , Knudtson Marguerite , Neylan Kyra , Brown Jesse , Allen Isabel Elaine , Rankin Katherine P. , Bonham Luke W. , Yokoyama Jennifer S. , Ramos Eliana M. , Geschwind Daniel H. , Spina Salvatore , Grinberg Lea T. , Miller Zachary A. , Kramer Joel H. , Rosen Howard , Gorno-Tempini Maria Luisa , Rabinovici Gil , Seeley William W. , Miller Bruce L.
Published: February 2023

Importance

The neurological substrates of visual artistic creativity (VAC) are unknown. VAC is demonstrated here to occur early in frontotemporal dementia (FTD), and multimodal neuroimaging is used to generate a novel mechanistic hypothesis involving dorsomedial occipital cortex enhancement. These findings may illuminate a novel mechanism underlying human visual creativity.

Objective

To determine the anatomical and physiological underpinnings of VAC in FTD.

Design, Setting, and Participants

This case-control study analyzed records of 689 patients who met research criteria for an FTD spectrum disorder between 2002 and 2019. Individuals with FTD and emergence of visual artistic creativity (VAC-FTD) were matched to 2 control groups based on demographic and clinical parameters: (1) not visually artistic FTD (NVA-FTD) and (2) healthy controls (HC). Analysis took place between September 2019 to December 2021.

Main Outcomes and Measures

Clinical, neuropsychological, genetic, and neuroimaging data were analyzed to characterize VAC-FTD and compare VAC-FTD with control groups.

Results

Of 689 patients with FTD, 17 (2.5%) met VAC-FTD inclusion criteria (mean [SD] age, 65 [9.7] years; 10 [58.8%] female). NVA-FTD (n = 51; mean [SD] age, 64.8 [7] years; 25 [49.0%] female) and HC (n = 51; mean [SD] age, 64.5 [7.2] years; 25 [49%] female) groups were well matched to VAC-FTD demographically. Emergence of VAC occurred around the time of onset of symptoms and was disproportionately seen in patients with temporal lobe predominant degeneration (8 of 17 [47.1%]). Atrophy network mapping identified a dorsomedial occipital region whose activity inversely correlated, in healthy brains, with activity in regions found within the patient-specific atrophy patterns in VAC-FTD (17 of 17) and NVA-FTD (45 of 51 [88.2%]). Structural covariance analysis revealed that the volume of this dorsal occipital region was strongly correlated in VAC-FTD, but not in NVA-FTD or HC, with a volume in the primary motor cortex corresponding to the right-hand representation.

Conclusions and Relevance

This study generated a novel hypothesis about the mechanisms underlying the emergence of VAC in FTD. These findings suggest that early lesion-induced activation of dorsal visual association areas may predispose some patients to the emergence of VAC under certain environmental or genetic conditions. This work sets the stage for further exploration of enhanced capacities arising early in the course of neurodegeneration.
Myocarditis or Pericarditis Events After BNT162b2 Vaccination in Individuals Aged 12 to 17 Years in Ontario, Canada
Authors: Buchan Sarah A. , Alley Sarah , Seo Chi Yon , Johnson Caitlin , Kwong Jeffrey C. , Nasreen Sharifa , Thampi Nisha , Lu Diane , Harris Tara M. , Calzavara Andrew , Wilson Sarah E.
Published: February 2023

Importance

The risk of myocarditis or pericarditis after COVID-19 messenger RNA vaccines varies by age and sex, and there is some evidence to suggest increasing risk with shorter intervals between dose 1 and 2 (ie, interdose interval).

Objective

To estimate the incidence of reported myocarditis or pericarditis after BNT162b2 vaccine among adolescents and to describe the clinical information associated with these events.

Design, Setting, and Participants

This was a population-based cohort study using passive vaccine safety surveillance data linked to the provincial COVID-19 vaccine registry. Included in the study were all adolescents aged 12 to 17 years in Ontario, Canada, who received 1 or more doses of BNT162b2 vaccine between December 14, 2020, and November 21, 2021, and reported an episode of myocarditis or pericarditis. Data were analyzed from December 15, 2021, to April 22, 2022.

Exposure

Receipt of BNT162b2 (Comirnaty [Pfizer-BioNTech]) vaccine.

Main Outcomes and Measure

Reported incidence of myocarditis or pericarditis meeting level 1 to 3 of the Brighton Collaboration case definition per 100 000 doses of BNT162b2 administered by age group (12-15 years vs 16-17 years), sex, dose number, and interdose interval. All clinical information associated with symptoms, health care usage, diagnostic test results, and treatment at the time of the acute event were summarized.

Results

There were approximately 1.65 million doses of BNT162b2 administered and 77 reports of myocarditis or pericarditis among those aged 12 to 17 years, which met the inclusion criteria during the study period. Of the 77 adolescents (mean [SD] age, 15.0 [1.7] years; 63 male individuals [81.8%]), 51 (66.2%) developed myocarditis or pericarditis after dose 2 of BNT162b2. Overall, 74 individuals (96.1%) with an event were assessed in the emergency department, and 34 (44.2%) were hospitalized (median [IQR] length of stay, 1 [1-2] day). The majority of adolescents (57 [74.0%]) were treated with nonsteroidal anti-inflammatory drugs only, and 11 (14.3%) required no treatment. The highest reported incidence was observed among male adolescents aged 16 to 17 years after dose 2 (15.7 per 100 000; 95% CI, 9.7-23.9). Among those aged 16 to 17 years, the reporting rate was highest in those with a short (ie, ≤30 days) interdose interval (21.3 per 100 000; 95% CI, 11.0-37.2).

Conclusions and Relevance

Results of this cohort study suggest that there was variation in the reported incidence of myocarditis or pericarditis after BNT162b2 vaccine among adolescent age groups. However, the risk of these events after vaccination remains very rare and should be considered in relation to the benefits of COVID-19 vaccination.
Distributed adaptive estimation without persistence of excitation: An online optimization perspective
Authors: Garg Tushar , Basu Roy Sayan
Published: February 2023

This work proposes a distributed adaptive estimation algorithm for multi‐agent system (MAS) architecture using online measurements in a continuous‐time setting. Classical adaptive parameter estimation algorithms demand to satisfy persistence of excitation (PE) or its distributed variant cooperative persistent of excitation (C‐PE) for parameter convergence. PE, C‐PE, are restrictive in nature since it requires excitation (richness of information content) over the entire time span of the signal/data, making it unrealistic in most real‐world applications, especially in robotics and cyber‐physical systems. Unlike past literature, the proposed work ensures parameter convergence under a slackened condition, coined as cooperative initial excitation (C‐IE), which demands information richness only in the initial time‐window (transient period) suitable for practical scenarios. A distributed differential parameter estimator algorithm is designed, which with the help of stable closed‐loop filter dynamics and strategic switching guarantees global exponential stability (GES) of the parameter estimation error dynamics in the sense of Lyapunov. The formulation is further augmented by providing an online optimization perspective. A novel cost function is constructed in such a way that the proposed distributed parameter estimator acts as a distributed continuous‐time gradient‐descent algorithm based on the cost function and the true uncertain parameter vector is the global minima of the cost function. Simulation results validate the efficacy of the proposed algorithm in contrast to the PE/C‐PE based methods.
Mo‐Modified ZnIn2S4@NiTiO3 S‐Scheme Heterojunction with Enhanced Interfacial Electric Field for Efficient Visible‐Light‐Driven Hydrogen Evolution
Authors: Zhu Jiafeng , Bi Qingyuan , Tao Yinghao , Guo Wenyao , Fan Jinchen , Min Yulin , Li Guisheng
Published: February 2023

Designing and developing visible‐light‐responsive materials for solar to chemical energy is an efficient and promising approach to green and sustainable carbon‐neutral energy systems. Herein, a facile in situ growth hydrothermal strategy using Mo‐modified ZnIn2S4 (Mo‐ZIS) nanosheets coupled with NiTiO3 (NTO) microrods to synthesize multifunctional Mo‐modified ZIS wrapped NTO microrods (Mo‐ZIS@NTO) photocatalyst with enhanced interfacial electric field (IEF) effect and typical S‐scheme heterojunction is reported. Mo‐ZIS@NTO catalyst possesses wide‐spectrum light absorption properties, excellent visible light‐to‐thermal energy effect, electron mobility, charges transfer, and strong IEF and exhibits excellent solar‐to‐chemical energy conversion for efficient visible‐light‐driven photocatalytic hydrogen evolution. Notably, the engineered Mo1.4‐ZIS@NTO catalyst exhibits superior performance with H2 evolution rate of up to 14.06 mmol g−1 h− 1 and the apparent quantum efficiency of 44.1% at 420 nm. The scientific explorations provide an in‐depth understanding of microstructure, S‐scheme heterojunction, enhanced IEF, Mo‐dopant facilitation effect. Moreover, the theoretical simulations verify the critical role of Mo element in promoting the adsorption and activation of H2O molecules, modulating the H adsorption behavior on active S sites, and thus accelerating the overall catalytic efficiency. The photocatalytic hydrogen evolution mechanism via S‐scheme heterojunction with adjustable IEF regulation over Mo1.4‐ZIS@NTO is also demonstrated.
Self‐Rolling‐Up Enabled Ultrahigh‐Density Information Storage in Freestanding Single‐Crystalline Ferroic Oxide Films
Authors: Guo Yunting , Peng Bin , Qiu Ruibin , Dong Guohua , Yao Yufei , Zhao Yanan , Zhou Ziyao , Liu Ming
Published: February 2023

Ferroelectric memory is one of the most attractive emerging nonvolatile memory. Conventional methods to increase storage density in ferroelectrics include reducing the storage bit size or fabricating 3D stacks. However, the former will face a physical limit finally, and the integration of single‐crystalline ferroelectric oxide following the latter still remains a great challenge. Here, a new method is introduced to construct a scroll‐like 3D memory structure by self‐rolling‐up single‐crystalline ferroelectric oxides. PbZr0.3Ti0.7O3 single‐crystalline thin film is chosen as a prototype and epitaxially grown on another oxide stressor layer with a few lattice‐mismatch. Releasing such “Pb(Zr, Ti)O3/stressor” bilayered structure from the substrate induces self‐rolling‐up due to the internal stress from the lattice‐mismatch. High‐density information can be written in the form of switched ferroelectric domains on those flat “Pb(Zr, Ti)O3/stressor” membranes via piezoelectric force microscopy. In self‐rolling‐up membranes, information density can be experimentally enhanced up to 45 times. Theoretically, the freestanding “Pb(Zr, Ti)O3/stressor” membranes have a strongly driven force to self‐rolling‐up, and the area ratio can enhance 100–450 times, corresponding to an ultra‐high density information storage of 102 Tbit In−2. This study provides a new and general method to develop compact, high‐density, and 3D memories from oxide materials.
Composition and Structure Design of Poly(vinylidene fluoride)‐Based Solid Polymer Electrolytes for Lithium Batteries
Authors: Zhou Shengyu , Zhong Shijie , Dong Yunfa , Liu Zhezhi , Dong Liwei , Yuan Botao , Xie Haodong , Liu Yuanpeng , Qiao Liang , Han Jiecai , He Weidong
Published: February 2023

Solid‐state lithium batteries have become the focus of the next‐generation high‐safety lithium batteries due to their dimensional, thermal, and electrochemical stability. Thus, the progress of solid electrolytes with satisfactory comprehensive performances has become the key to promoting the development of solid batteries. Herein, poly(vinylidene fluoride) (PVDF) solid polymer electrolytes (SPEs) possess excellent flexibility, mechanical property, and high electrochemical and thermal stability, which show huge application potentiality in solid‐state lithium batteries and obtain extensive research. But the PVDF SPEs have been suffering from low ionic conductivity, high crystallinity, and low reactive sites. The development of PVDF‐based composite solid polymer electrolytes (CSPEs) has been confirmed to be a forceful strategy to optimize the performance of electrolytes. In this review, based on different design strategies, the recent progress of PVDF‐based SPEs is introduced in detail, especially in the mechanism of ionic conductivity enhancement and interface regulation by modified fillers. Besides, the applications of PVDF‐based SPEs in Li‐S and Li‐O2 battery systems are also introduced. Finally, this review presents some insights for promoting the development of high‐performance PVDF‐based SPEs.
n‐Type Glycolated Imide‐Fused Polycyclic Aromatic Hydrocarbons with High Capacity for Liquid/Solid‐Electrolyte‐based Electrochemical Devices
Authors: Yu Yaping , Zhu Genming , Lan Liuyuan , Chen Junxin , Zhu Xiuyuan , Duan Jiayao , Cong Shengyu , Li Zhengke , Wang Yunxia , Wang Zhaohui , McCulloch Iain , Yue Wan
Published: February 2023

Currently, n‐type small‐molecule mixed ionic‐electronic conductors remain less explored and their molecular design rules are not mature enough. Herein, two n‐type glycolated imide‐fused polycyclic aromatic hydrocarbons (IPAHs), d‐gdiPDI and t‐gdiPDI, are developed to probe the effects of molecular conformation on the electronic, electrochemical, morphological, and coupled ionic‐electronic transport properties. It is found that the highly twisted scaffold in d‐gdiPDI, compared to the nearly planar one of t‐gdiPDI, has a strong positive effect on the charge storage properties and thus the performance of organic electrochemical transistors (OECTs). d‐gdiPDI exhibits a volumetric capacitance of 657 F cm−3, obviously outperforming that of t‐gdiPDI (261 F cm−3), which is the highest value reported to date for small‐molecule OECT materials. Moreover, a high charge‐storage capacity of up to 479 F g−1 is observed for d‐gdiPDI. Arising from such high ionic‐electronic coupling characteristic, d‐gdiPDI‐based OECTs present a ≈2 × times higher geometry‐normalized transconductance (gm,norm) of 105.3 mS cm−1 relative to that of t‐gdiPDI counterparts. Significantly, further application of d‐gdiPDI in solid‐electrolyte OECTs delivers a gm,norm of 142.4 mS cm−1. These findings indicate that IPAHs are very promising candidates for n‐type small‐molecule OECTs and highlight the superiority of twisting conformation manipulation in materials design toward high‐performance electrochemical devices.
Incorporating Tantalum Oxide Nanoparticles into Implantable Polymeric Biomedical Devices for Radiological Monitoring
Authors: Pawelec Kendell M. , Tu Ethan , Chakravarty Shatadru , Hix Jeremy M. L. , Buchanan Lane , Kenney Legend , Buchanan Foster , Chatterjee Nandini , Das Subhashri , Alessio Adam , Shapiro Erik M.
Published: February 2023

Longitudinal radiological monitoring of biomedical devices is increasingly important, driven by the risk of device failure following implantation. Polymeric devices are poorly visualized with clinical imaging, hampering efforts to use diagnostic imaging to predict failure and enable intervention. Introducing nanoparticle contrast agents into polymers is a potential method for creating radiopaque materials that can be monitored via computed tomography. However, the properties of composites may be altered with nanoparticle addition, jeopardizing device functionality. Thus, the material and biomechanical responses of model nanoparticle‐doped biomedical devices (phantoms), created from 0–40 wt% tantalum oxide (TaOx) nanoparticles in polycaprolactone and poly(lactide‐co‐glycolide) 85:15 and 50:50, representing non, slow, and fast degrading systems, respectively, are investigated. Phantoms degrade over 20 weeks in vitro in simulated physiological environments: healthy tissue (pH 7.4), inflammation (pH 6.5), and lysosomal conditions (pH 5.5), while radiopacity, structural stability, mechanical strength, and mass loss are monitored. The polymer matrix determines overall degradation kinetics, which increases with lower pH and higher TaOxcontent. Importantly, all radiopaque phantoms could be monitored for a full 20 weeks. Phantoms implanted in vivo and serially imaged demonstrate similar results. An optimal range of 5–20 wt% TaOxnanoparticles balances radiopacity requirements with implant properties, facilitating next‐generation biomedical devices.
Influence of Pore Size in Protein G'‐Grafted Mesoporous Silica Nanoparticles as a Serum Pretreatment System for In Vitro Allergy Diagnosis
Authors: Paris Juan L. , Monío Cristina , Pérez‐Moreno Ana M. , Jurado‐Escobar Raquel , Bogas Gador , Fernández Tahía D. , Montañez María I. , Mayorga Cristobalina , Torres María J.
Published: February 2023

Particles with the capacity to bind to immunoglobulin G (IgG) can be used for the purification of IgG or to process clinical samples for diagnostic purposes. For in vitro allergy diagnosis, the high IgG levels in serum can interfere with the detection of allergen‐specific IgE, the main diagnostic biomarker. Although commercially available, current materials present a low IgG capture capacity at large IgG concentrations or require complex protocols, preventing their use in the clinic. In this work, mesoporous silica nanoparticles are prepared with different pore sizes, to which IgG‐binding protein G’ is grafted. It is found that for one particular optimal pore size, the IgG capture capacity of the material is greatly enhanced. The capacity of this material to efficiently capture human IgG in a selective way (compared to IgE) is demonstrated in both solutions of known IgG concentrations as well as in complex samples, like serum, from healthy controls and allergic patients using a simple and fast incubation protocol. Interestingly, IgG removal using the best‐performing material enhances in vitro IgE detection in sera from patients allergic to amoxicillin. These results highlight the great translation potential of this strategy to the clinic in the context of in vitro allergy diagnosis.
Coupled Tamm Phonon and Plasmon Polaritons for Designer Planar Multiresonance Absorbers
Authors: He Mingze , Nolen Joshua Ryan , Nordlander Josh , Cleri Angela , Lu Guanyu , Arnaud Thiago , McIlwaine Nathaniel S. , Diaz‐Granados Katja , Janzen Eli , Folland Thomas G. , Edgar James H. , Maria Jon‐Paul , Caldwell Joshua D.
Published: February 2023

Wavelength‐selective absorbers (WS‐absorbers) are of interest for various applications, including chemical sensing and light sources. Lithography‐free fabrication of WS‐absorbers can be realized via Tamm plasmon polaritons (TPPs) supported by distributed Bragg reflectors (DBRs) on plasmonic materials. While multifrequency and nearly arbitrary spectra can be realized with TPPs via inverse design algorithms, demanding and thick DBRs are required for high quality‐factors (Q‐factors) and/or multiband TPP‐absorbers, increasing the cost and reducing fabrication error tolerance. Here, high Q‐factor multiband absorption with limited DBR layers (3 layers) is experimentally demonstrated by Tamm hybrid polaritons (THPs) formed by coupling TPPs and Tamm phonon polaritons when modal frequencies are overlapped. Compared to the TPP component, the Q‐factors of THPs are improved twofold, and the angular broadening is also reduced twofold, facilitating applications where narrow‐band and nondispersive WS‐absorbers are needed. Moreover, an open‐source algorithm is developed to inversely design THP‐absorbers consisting of anisotropic media and exemplify that the modal frequencies can be assigned to desirable positions. Furthermore, it is demonstrated that inversely designed THP‐absorbers can realize same spectral resonances with fewer DBR layers than a TPP‐absorber, thus reducing the fabrication complexity and enabling more cost‐effective, lithography‐free, wafer‐scale WS‐absorberss for applications such as free‐space communications and gas sensing.