bluuebunny/crossref_metadata_2025 huggingface dataset:
Surgical Approach to the Treatment of Upper Eyelid Retraction Caused by Prominent Filtration Bleb
Authors: Drabkin Elena , Andron Aleza
Published: April 2022

Objective: To report on the technique of upper eyelid lengthening in patients with upper eyelid retraction not associated with Graves' disease but associated with bleb exposure and exposure keratitis. Case series: We present three patients (four eyes) with a history of glaucoma who underwent trabeculectomy with an active bleb with symptoms associated with bleb and corneal exposure due to retraction of the upper eyelid not associated with Graves' disease. All patients underwent surgical treatment to lengthen the upper eyelid by percutaneous complete blepharotomy with complete dissection of the orbicularis muscle, aponeurosis of levator palpebral muscle, Muller’s muscle and dissection of nasal and temporal conjunctiva reaching the superior border of the tarsus. In addition, the lateral horns of the levator muscle were resected, while preserving a strip of intact conjunctiva directly above the bulging bleb. Before and after surgery, the following measurements were made: including, visual acuity, retraction measurement, presence symptoms of dry cornea and bleb, MRD, and upper eyelid contour. Results: Preoperative upper lid marginal reflex distance (MRD) was measured. In addition, conjunctival staining of the bleb and cornea was recorded. Visual acuity ranged from 6/12 to 6/36. Upper eyelid retraction ranged from 3mm to 7.5mm, this was measured by calculating the marginal reflex distance (MRD) of the upper retracted eyelid minus 4.5 mm, representing the normal MRD. Amounts of lubricating drops used by patients per day was also recorded and quantified. The following postoperative measurements were recorded: MRD of upper eyelid; specifically including upper eyelid contour and position, present or absence of upper eyelid ptosis. Visual acuity improved by one line in the first postoperative week and maximum up to three lines after a month. A good cosmetic result was achieved. Conclusion: Blepharotomy is a surgical procedure suitable for the treatment of severe eyelid retraction. Preservation of the bridge of the intact conjunctiva over the bleb protects the bleb from traumatization in the postoperative period. This makes possible to use the blepharotomy in cases of eyelid retraction with exposure of the filtration bleb, and also maintain the correct contour of the upper eyelid.
Effect of bioactive glass-based composite and low energylaser on bone regeneration in an experimentally induced bone defect
Authors: Konovalenko Sergey , Protsenko Volodymyr , Solonitsyn Yevgen , Osadchuk Taras , Konovalenko Volodymyr , Omelchenko Taras
Published: April 2022

In vivo experimental study was conducted to investigate the effect of bone regeneration under the use of a bioactive glass-based composite as well as the use of laser irradiation in the presence of the bioactive glass-based composite. In 16 white non-inbred rats, with a body weight of 300–350 g the bioactive glass-based composite was implanted into the tibial metaphysis. Besides, 90 female rats of the Wistar line weighing 250–270 g underwent laser irradiation on an artificially created tibial bone defect filled with the bioactive glass-based composite. The period of observation lasted respectively 2 and 4 weeks. It was found that application of the bioactive glass promotes bone regeneration, which is noticeably enhanced with the use of low energy laser. The combining effect leads to a significant increase in bone regeneration and the expression of bone tissue metabolic markers: osteocalcin and alkaline phosphatase. The most pronounced effect of the laser on bone regeneration occurred at a wavelength of 810 nm, which opens up prospects for the use of this technique in clinical practice.
IMPLEMENTATION OF NEUROMUSCULAR DENTISTRY PRINCIPLES IN REHABILITATION OF PATIENTS WITH COMPLETE ADENTIA
Authors: Domenyuk Dmitry , Kochkonyan Taisiya , Rozhkova Maria , Fischev Sergey , Lepilin Alexandr , Sevastyanov Arkady , Orlova Irina , Puzdyreva Margarita , Subbotin Roman , Dmitrienko Sergei , Domenyuk Stanislav
Published: April 2022

According to World Health Organization about 15% of the world’s adult population suffer from complete adentia, with a steady growth in the number of patients affecting not only the elderly which is accounted for by an increase in life expectancy, yet also among people in their working age. Apart from disturbed chewing and speech functions, complete adentia leads to altered anatomical and topographic proportions of the face and facial skeleton, progressive atrophy and osteoporosis of the jaws, masticatory and mimic muscle atrophy, as well as to dysfunction affecting these muscles and temporomandibular joints. Due to lack of proper nutrition, changed exterior, issues in interaction with others, this group of patients develop a whole set of psychosomatic reactions finally causing social withdrawal. Rehabilitation of patients with complete loss of teeth is an urgent issue. However, the effectiveness of prosthetic treatment depends not only on the denture manufacturing technology, but on the quality of functioning involving the maxillofacial organs in combination with the respective orthopedic appliances. Whereas precise and reliable assessment of the maxillofacial neuromuscular balance enables to predict immediate and long-term outcomes of orthopedic treatment. Employing the principles of neuromuscular dentistry allows us to assess reliably the changes in the reflex mechanisms of muscular apparatus. This was carried out throughout all the stages of prosthetic treatment in patients with complete adentia with intraosseous implants with fixed bridges and conditionally removable denture.
La esfera de lo femenino. La introducción de detectives mujeres en Tuya, de Claudia Piñeiro
Authors: Bracamonte Jimena
Published: April 2022

En este artículo nos proponemos aplicar una categoría propia, la esfera de lo femenino. Esta noción hace referencia a la modelización de un mundo creado a partir de la escritura de mujeres con perspectiva de género, en la que se construyen y deconstruyen, aceptan y rechazan modelos de mujer y, en consecuencia, modos de ser, de estar y de devenir en la sociedad. Para ello abordaremos la escritura de la argentina Claudia Piñeiro, en particular de Tuya (2005), que presenta a una mujer detective. Centraremos la atención en el establecimiento de interrelaciones entre cuatro aspectos complejos del orden cultural: el género policial literario, su contexto actual de producción, los estudios de género y la perspectiva semiótica de Iuri Lotman.
La sexualidad del rostro: revelación artificial y desprogramación material
Authors: Voto Cristina
Published: April 2022

El artículo propone, desde una perspectiva de género, un análisis semiótico de la performatividad de la visión artificial en el ámbito de la producción de imágenes en la era digital. A partir de una puesta en diálogo entre la investigación basada en la inteligencia artificial Deep Neural Networks are More Accurate Than Humans at Detecting Sexual Orientation From Facial Images, de Michal Kosinski y Yilun Wang, de la Universidad de Stanford y la exhibición “Sexo, imagen y algoritmos: homosexual data”, del artista chileno Felipe Rivas San Martín, se busca reflexionar sobre el actual proceso de algoritmización de la identidad sexual y genérica y opacar las retóricas transparentes y reveladoras de la inteligencia artificial por medio de la práctica artística.
¿Feminismo y gestos vacíos? Series de TV y desbordes de la condición femenina
Authors: Ponce Ariel Gómez
Published: April 2022

El artículo problematiza el modo en que las series televisivas actuales escenifican ciertos desbordes subjetivos en su lectura de la condición femenina. Se propone un acercamiento transversal a los estudios de género recuperando aportes de la semiótica de Yuri Lotman, enclave fértil para interpelar una memoria cultural que ha modelizado el empoderamiento femenino como desborde afectivo y tiranía política. En torno al desenlace de Game of Thrones, el trabajo se interroga por ficciones populares que encierran la promesa de un feminismo y de alternativas a una heteronormatividad tradicional, pero que terminan volviendo esta demanda social y política una operación de mercado.
https://www.designisfels.net/capitulo/i36-18-la-recepcion-de-teoria-king-kong-de-virginie-despentes-en-espana-clubs-de-lectura-y-emancipacion-en-la-era-post-metoo/
Authors: Marc Isabelle
Published: April 2022

En el contexto de la denominada era post #MeToo (Murat, 2018), este trabajo pretende explorar cómo se ha recibido en España Teoría King Kong, de Virginie Despentes, uno de los libros sobre feminismos más polémicos y más leídos en los dos últimos años. El estudio de dicha recepción se realizará, por un lado, a partir de la cobertura del texto por parte de los medios españoles y, por otro, y principalmente, por medio del análisis de una serie de clubs de lectura realizados en Madrid en 2018 y en 2019. Se analizarán así los asuntos que suscitan mayor interés y debate en el libro, principalmente la violencia sexual y la prostitución, y cómo reaccionan lxs lectorxs en función de repertorios ideológicos y emocionales previos a la lectura. El objetivo consiste, pues, en entender en qué medida textos como Teoría King Kong funcionan a la vez como causa y como efecto de las reivindicaciones feministas, convertidas en problemas públicos (Cefaï, 2016) en la actualidad.
Más allá del lenguaje. La contribución de la semiótica al movimiento feminista a partir del estudio de las prácticas
Authors: Barreneche Sebastián Moreno
Published: April 2022

Partiendo de una discusión sobre el rol protagónico que el feminismo tiene en el escenario político contemporáneo, en este artículo se argumenta cómo la semiótica puede contribuir con el proyecto feminista mediante la identificación, el análisis y el desmontaje de las estructuras profundas de sentido subyacentes a los roles de género (especialmente el femenino). A partir de la concepción del movimiento feminista como una identidad política colectiva enmarcada en una disputa por el significado, se propone una expansión de la mirada semiótica más allá del lenguaje y se abarcan prácticas significantes y otros niveles de inmanencia. El argumento se ilustra mediante el ejemplo de las prácticas de autosexualización.
“Ahora que sí nos ven”: categorías para el abordaje semiótico de las movilizaciones feministas
Authors: Bucio Claudia Ivette Pedraza , Aguilar Raúl Roydeen García
Published: April 2022

La pugna semio-discursiva por el espacio público que suponen las acciones y lecturas de las movilizaciones feministas suscita la necesidad de un conjunto de categorías mínimas para su abordaje teórico y analítico, tanto en el ámbito del reconocimiento como en el del compromiso existencial. A partir de la contextualización histórica y conceptual, proponemos para la comprensión de la movilización feminista los siguientes aspectos: identidades múltiples en espacios fractales; el conflicto entre la búsqueda de reconocimiento de las mujeres versus las representaciones habituales de la mujer; las relaciones entre signos indiciales y simbólicos; y la consideración complementaria de la acción estratégica y la experiencia de las participantes
Los acuerdos afectivos y el desarrollo de las controversias públicas. La rabia feminista
Authors: Echezarreta Vanesa Saiz , Lorenzini Paulina Gómez
Published: April 2022

La controversia sobre la prostitución se articula en diversas arenas públicas (académicas, activistas e institucionales) siguiendo patrones de actuación ritualizados que derivan de un estilo y de una resonancia afectivos marcados, desde la Conferencia de Barnard, de 1982, por la ira y la indignación. Esta tonalidad o flow afectivo, que desde el enfrentamiento define la relación entre el movimiento abolicionista y el proderechos en el seno del feminismo, genera un acuerdo afectivo que modula las disposiciones emocionales de los participantes y la intensidad afectiva del debate. Desbloquear la controversia implica cuestionar el acuerdo vigente, indagar en los afectos y emociones comunes, para abrir espacios desde los cuales imaginarse un horizonte compartido.
Perspectivas semióticas de feminificción: voces femeninas en la minificción hispanoamericana (Argentina, México, Chile)
Authors: Bustamante Luisa Marisol Fuentes , Paleologos Konstantinos , Xouplidis Panagiotis
Published: April 2022

Durante el siglo XX, en el continente americano floreció la narrativa hiperbreve, la minificción, mientras en el siglo XXI las escritoras se involucran activamente en la creación de minicuentos. A través de la crítica feminista, este artículo ofrece una perspectiva semiótica sobre la minificción en español por escritoras de Argentina, México y Chile en el siglo XXI. Su objetivo es promover el diálogo crítico sobre un género literario pionero con una presencia significativa en la literatura hispanoamericana, con el fin de destacar su importante contribución en la reivindicación de la voz del sujeto femenino en América Latina.
Cytotoxicity of plasma-irradiated lactate solution produced under atmospheric airtight conditions and generation of the methyl amino group
Authors: Ito Daiki , Iwata Naoyuki , Ishikawa Kenji , Nakamura Kae , Hashizume Hiroshi , Miron Camelia , Tanaka Hiromasa , Kajiyama Hiroaki , Toyokuni Shinya , Mizuno Masaaki , Hori Masaru
Published: April 2022

Ringer’s lactate solution was irradiated with non-equilibrium plasma under airtight conditions. The plasma-activated lactate (PAL) was produced with argon, oxygen, and nitrogen gases following purging of Ar. Cytotoxicity could be controlled by diluting PAL, and a killing effect was selectively obtained on cancer cells compared to normal cells for Ar+O2+N2 PALs. Nonetheless, cytotoxicity was partly reproduced by similar concentrations of H2O2 and NO2
− in the PALs. The organics produced by plasma irradiation to lactate were investigated using nuclear magnetic resonance, and the generation of methyl amino species was confirmed.
Risiko Politik Identitas Terhadap Pluralisme Di Indonesia
Authors: Basri Junaidin , Basri Syakira Ainun Nisa , Indriyani Irma
Published: April 2022

Penelitian ini bertujuan untuk mengungkap gambaran risiko yang terjadi ketika politik identitas berkembang di Indonesia. Untuk mweujudkan tujuan penelitian, metode yang digunakan adalah kualitatif dengan pendekatan deskriptif. Hasil penelitian menyimpulkan bahwa: Politik identitas adalah politik yang pada dasarnya menganut persamaan identitas untuk menaikkan derajat suatu kelompok karena adanya rasa tidak berharga, politik ini telah mengalami perkembangan yang sebelumnya mengangkat derajat kelompok tertentu menjadi alat politik yang ditunggangi. oleh elit politik untuk keuntungan pribadi dan untuk mendapatkan suara pada saat pemilu, sedangkan Pluralisme adalah kondisi masyarakat yang dapat hidup berdampingan dalam masyarakat yang beragam sehingga masyarakat dapat hidup rukun. Pluralisme dalam suatu bangsa cukup penting, terutama di wilayah yang multi etnis, agama, ras, dan antar golongan agar dapat hidup berdampingan satu sama lain, sedangkan risiko yang dapat ditimbulkan dari politik identitas menuju pluralisme adalah hilangnya atau memudarnya pluralisme itu sendiri. menimbulkan risiko lain, seperti hilangnya toleransi antar masyarakat, dapat menimbulkan kekerasan fisik maupun non fisik, munculnya gerakan disintegrasi rumah tangga, dan risiko terburuk adalah kehancuran suatu negara.
Determination of Higher Heating Value by calculation based on elemental analysis
Authors: Kalivodová Markéta , Baláš Marek , Milčák Pavel , Lisá Hana , Lisý Martin , Lachman Jakub , Kracík Petr , Križan Peter , Vejražka Karel
Published: April 2022

Biomass has increasingly been used as a renewable energy source, and the possibility of using waste ma-terials for energy purposes has recently been highlighted. Therefore, it is necessary to know the properties of these fuels. The most important is the Higher Heating Value (HHV), and also the Lower Heating Value (LHV), which expresses the amount of energy stored in the fuel. These are determined by an experiment but can also be determined by calculation. This paper deals with the comparison of existing equations for the calculation of HHV with the value determined experimentally by a calorimetric method. The suitability of using the given equation for the given fuels is evaluated. Based on the results of the applied equations, some of them are selected and recommended for the calculation of certain fuels.
Relating Mandelbrot and Barnes-Jarvis Power Law Noise State Space Models using Partial Fractions
Authors:   Department of Physics and Electronics, National University of Lesotho (NUL), Roma, Lesotho., Matjelo Naleli Jubert , Moeti Sekhonyana ,   Department of Engineering, Minopex Lesotho Pty (LTD), Mokhotlong, Lesotho., Mokhomo Molise ,   Mukuru, Cape Town, Western Cape, South Africa.
Published: April 2022

This paper addresses two state space models for generating approximate power law noise and shows that these models are related through partial fractions in frequency domain.
Exploration on Document Taxonomy by Ganb Algorithm
Authors:   Assistant Professor, Department of Computer and Information Science, Annamalai University, Annamalai Nagar, India., Babu Dr. R. Sathish
Published: April 2022

In this research, we propose an integrated classification GANB algorithm that combines a feature extractor with a classifier to construct a classification model. The feature extractor automates the examination of raw pre-processed unstructured documents. Following feature extraction, categorization generates meaningful classes based on the supplied features. The study uses a genetic algorithm (GA) for feature extraction and Naïve Bayes(NB) for classification purposes. The simulation evaluates the suggested classification model's accuracy, sensitivity, specificity, and f-measure using various performance indicators. Over the Medline cancer datasets, the suggested GANB gets a higher classification rate than existing approaches.
Effect of Local Coarse Aggregate Type on Concrete Mechanical Properties in Bangladesh
Authors:   Department of Civil Engineering, Ahsanullah University of Science and Technology, Dhaka-1208, Bangladesh., Patowary Faruk , Mahmood Raqib Al ,   Department of Civil Engineering, Ahsanullah University of Science and Technology, Dhaka-1208, Bangladesh.
Published: April 2022

Different types of natural coarse aggregate are available in the local market of Bangladesh, which are primarily imported from several regions of the neighboring country, India. This paper aims to find the best locally available natural coarse aggregate for concrete preparation in terms of mechanical strength. It also reports on the results of an experiment investigation that looked at the effects of six different types of natural coarse aggregate, namely Burimari, Bhurungamari, Bholaganj, Tamabil, Jaflong and Dinajpur Hili (Indian Black Stone), available in the local market of Bangladesh on the mechanical properties of concrete. Concrete cylindrical specimens of 100mm diameter were prepared by each type of natural coarse aggregate keeping other ingredients constant. Concrete mix ratio and water/cement ratio adopted for the study were 1:1.5:3 and 0.48, respectively. The Compressive strength, splitting tensile strength and modulus of elasticity were investigated at 7, 14 and 28 days of curing age. The obtained results showed Dinajpur Hili (Indian Black Stone) is most suitable for concreting having distinguished variation in compressive strength, splitting tensile strength and modulus of elasticity compared to other types of natural coarse aggregates used in the research.
Feedabck Analysis: A Process Definition
Authors:   Faculty Member, Department of Business Administration, University of Kalyani, West Bengal, India, Biswas Mr. Biswaji , Rakshit Mr. Debjit ,   P.G. Student, Department of Business Administration, University of Kalyani, West Bengal, India.
Published: April 2022

Customers Feedbacks take an important role for any business. It gives information to the new customers about their interactions with product or service. The objectives of this research work are to find out the degree of happiness of the customers and assist marketing teams in determining the gap between customers’ acceptance and product or service quality. From this gap marketers can improve their product and service quality. Customers share their reviews, ideas, experiences about the product and service quality. In this research work, authors have chosen an automobile service station named Mohan Automobile Service Station, West Bengal. In this research work authors have collected the customers feedback through questioners created in Google form. The collected feedbacks are validated and analyzed to know the insight sentiment using Python Monkey Learn tools. The result of the collected feedback is shown as positive, negative, or neutral based on the polarity of the feedback. The result will be helpful for the service station to know their weak point and they can update their service quality.
Raga Classification Based on Novel Method of Pitch Co-Occurrence
Authors:   Department of E&TC, Modern College of Engineering, Pune (Maharashtra), India., Rajadnya Vibhavari , Joshi Dr. Kalyani ,   Department of E&TC, Modern College of Engineering, Pune (Maharashtra), India.
Published: April 2022

Automatic identification of raga is a growing research area and has captured significant attention from movie making industry. It is the need of time to develop efficient tools for data mining the vast audio visual data on internet. In particular, to search for a specific raga. Applications of raga search are in musicological studies, similarity based search. Ascending and descending pattern of swaras is an important feature in the raga classification. Pitch tracks of swaras are obtained from raw audio recordings. This research has utilised the pattern developed due to co-occurrence of pitches of swaras for classification. This pattern gives a concise representation of the signal which contains time and frequency information of the raga. K Nearest Neighbour (KNN) has been used as the classifier.
Artificial Intelligence and Machine Learning Based Models for Prediction and Treatment of Cardiovascular Diseases: A Review
Authors:   Associate Professor, Department of Electronics & Communication Engineering, Siddartha Educational Academy Group of Institutions, C. Gollapalli, Tirupati (A.P), India., Gandham Dr. Sreedevi , Meriga Dr. Balaji ,   Associate Professor, Department of Biochemistry, Sri Venkateswara University, Tirupati (A.P), India.
Published: April 2022

Advances in Machine Learning (ML) algorithms, computing and Artificial Intelligence (AI)-based systems have been gradually finding applications in several domains including medical and health care systems. By using big data analytics and machine learning methodologies, AI has become a promising tool in the diagnosis and treatment of cardiovascular diseases. AI-ML based applications enhance our understanding of different parameters and phenotypes of heart diseases and lead to newer therapeutic strategies to tackle different types of cardiovascular ailments, a newer approach to cardiovascular drug therapy and a post-marketing survey of prescription drugs. Although AI has wide range of applications, it is in infant stage and has certain limitations in the clinical use of results and their interpretations such as data privacy, selection bias etc, which may result in wrong conclusions. Thus, AI-ML is a transformative technology and has immense potential in health care systems. This review covers various aspects of cardiovascular diseases (CVDs) and illustrate AI and ML based methods including supervised, unsupervised and deep learning and their applications in cardiovascular imaging, cardiovascular risk prediction and newer drug targets.
Channel Estimation for DS-CDMA Rake Receiver using Sparse Recovery Approach
Authors:   Department of E&TC, Sanjivani Engineering College, Kopargaon (Maharashtra), India., Zope Rajendrakumar Govinda , Agarkar Balasaheb Shrirangrao ,   Department of E&TC, Sanjivani Engineering College, Kopargaon (Maharashtra), India.
Published: April 2022

In the literature of direct-sequence code-division multiple-access (DS-CDMA), for issues related to channel estimation, some exclusive architectures have been proposed, which are characterized by known channel noise statistics and noise observation. But in reality, the channel parameters are frequently assessed utilizing training sequences that lead to difficulty in obtaining the channel noise statistics. Channel estimation quality has been proved to play an important role in the performance of rake receiver. This paper addresses the issues of optimizing DS–CDMA rake receiver channel estimation equipped with an Iterative least square sparse recovery (IL2SR) channel estimator. Moreover, the ambient noises corrupt the signal received and multiple-access interference further aggravates it. Because of this observation noises become hard to acquire. Hence this paper proposes as an iterative least square structure for channel estimation algorithm in rake receiver employed in DS-CDMA communication systems. Further, examination of blind channel estimation problem for rake-based DS-CDMA communication framework having multi-path fading channels with time variation is also attempted. The validity of the proposed techniques has been verified through results obtained from simulation for different channel parameters and spreading codes. Further exploration has been carried out with execution of the IL2SR with Rake receiver in DS-CDMA framework for multi-path fading channels. It is found that better performance is obtained with this framework under various channels with different spreading codes. The proposed system is compared with Kalman based techniques and it was found that DS-CDMA framework under additive white gaussian noise (AWGN)channel with IL2SR receiver reveals better outcomes in terms of bit error rate (BER). Also, there has been improvement in video quality while using the proposed IL2SR receiver with increase in the values of ratio of signal to noise ratio.
Bistability of Cavity Magnonics System with Magnon Kerr Effect
Authors:   Department of Physics, Vidyasagar University, Midnapore, India., Ganthya Debabrata , Parai Arumay ,   Department of Physics, Vidyasagar University, Midnapore, India., Jana Paresh Chandra ,   Department of Physics, Vidyasagar University, Midnapore, India.
Published: April 2022

In this study a comprehensive theory is developed for a hybrid cavity magnonics system consisting of a microwave cavity strongly coupled to spin excitations or magnons in a single-crystal yttrium iron garnet (YIG) sample with the magnons exhibiting nonlinear Kerr effect caused by magnetocrystalline anisotropy in YIG. The system dynamics is analysed in Hamilton Langevin formulation and it is shown that the magnon frequency shift due to Kerr nonlinearity is bistable with a upper and a lower branch of cavity magnon polaritons (CMP). Further by analytically and graphically studying different conditions imposed on the bistability equation it is demonstrated that the bistability is controllable by tuning the system parameters involved.
Interpreting the predictions of Deep Network build to identify early detection of Covid-19 in X-Ray Images
Authors: bansal Vipin
Published: April 2022

AI is proven technology which is currently serving many different industries. Weather forecasting, recommendation system, autonomous car are few of the examples where AI driven solutions are successfully used. Availability of intensive computing makes it possible to design and develop highly complicated deep learning architecture which is desire to reach human level of accuracy. Because of this reason it become possible to utilize AI technology in healthcare industry where accuracy is utmost important. Healthcare industry generates various types of Electronic Health Records (EHR) like patient medical history, hospital administration data, biological data, radiological data etc. These type of EHR data can have huge potential in diagnosis various diseases and potentially avoiding any critical risk. AI is also contributing significantly on drug discovery, understanding genetic disorder, cancer detection and many more. All such complex use case needs a complex AI-Deep Neural Network (DNN). Due to its complex architecture these DNN models considered as black box and it became difficult to explain the outcome of such models. Entrust on such solutions considered as a major concern area. Various techniques have been evolved that try to explain the reasoning behind the outcome of such DNN. On this paper two such explanation techniques LIME and LRP is used on explain the prediction made on custom build CNN model. Custom CNN model is trained on Covid-19 patients X-RAY images. The main objective of this paper is to present the explanation difference made by LIME and LRP. Later domain experts can analyze the model predictions and facilities in improving the explanation techniques.
The Morphology of Lymphatic Endothelial Microchannels in the Renal Cortex of the Mouse
Authors: Pan Wei-Ren , Hu Nai-Ying , Liu Zhi-An , Ma Chuan-Xiang , Liu Zhi-Wei , Zhen Fei , Ge Yuhang , Ma Rui , Ni Kai-Xiang , Zeng Fan-Qiang
Published: April 2022

Background: The knowledge of the intrarenal lymphatic vasculature, especially the lymphatic endothelial microchannel, still remains unclear, that restricts the development of modern scientific research to support clinical management. Methods: Twelve kidneys harvested from 6 white mice were used for the investigation. Four kidneys were histologically sliced for hematoxylin-eosin, immunohistochemistry and immunofluorescence staining examinations. Four of them were sliced horizontally and coronally into 1mm thick tissues after ventricular perfusion was performed by a solution of 4% paraformaldehyde mixed with Indian ink, and then were inspected by a confocal laser scanning microscope after immunofluorescence staining followed by tissue clearing. Four were sliced and examined by scanning electron microscope. Results: The lymphatic vasculature has been detected in the renal tissue of the mouse. The arrangement of renal lymphatic vessels of the mouse was irregular in the cortex. In the 3-dimensional confocal image, many lymphatic endothelial microchannels were visible in the wall of segmental vessels. The ultra-structural feature of the lymphatic endothelial microchannel was noticed in the SEM image. Conclusion: The intrarenal lymphatic vascularture in the renal cortex of the mouse has been presented and the lymphatic endothelial microchannel has been described in detail. The results will provide basic knowledge of animal experiment for further scientific study and clinical applications.
Sleep Deprivation Affects Brain Acetylcholinesterase Activity and Cognitive Ability in Young and Aged Rats
Authors: Raina Neha , Chauhan Dushyant Singh , Tripathi Sandeep
Published: April 2022

Sleep plays an important role in maintaining neuronal circuitry, signalling and helps maintain overall health and wellbeing. Sleep deprivation (SD) disturbs the circadian physiology and exerts a negative impact on brain and behavioural functions. SD impairs the cellular clearance of misfolded neurotoxin various proteins which are involved in major neurodegenerative diseases like Alzheimer’s disease and Parkinson’s disease. SD aﬀects the immunological and redox system resulting in neuroinﬂammation and oxidative stress. The aim of the present study is to investigate sleep deprivation (SD) induced oxidative stress in different parts of the brain and in vivo behavioural changes associated with aging. Lipid peroxidation and reduced antioxidant status were significantly (p<0.05) increased along with the altered learning and memory ability. The most affected part of the brain was hippocampus followed by cerebral cortex. Acetyl cholinesterase was found to be altered in SD treated rats. These are remarkably correlated with the cognitive impairment. Aging is the affects more deleterious effect. It is also evident that SD induces premature aging in the study.
An Analysis of the Drug Distribution Model in the Public Health Services in Tamil Nadu
Authors: Manimegalai A. P.
Published: April 2022

Based on the field work in Tamil Nadu, this article analyses the procurement and dissemination functioning of the Tamil Nadu Medical Services Corporation (TNMSC), including the problems faced by different stakeholders’ viz. doctors, patients and pharmaceutical companies and also the stakeholders outside Tamil Nadu. The Tamil Nadu model of procurement and distribution of medicines under TNMSC is acclaimed as a successful model for its centralized-swift actions. However there were some inconsistencies hampering TNMSC to remain a model as there were the no availability of drugs as per approved essential drugs list, shortage and incomplete availability of drugs, and a shift from centralized procurement to local purchase arrangement of some drugs across Tamil Nadu. It also observed not only the quantity, quality and number of drugs procured and distributed, not matching with the health need of patients, but also the doses are not effective. In order to do that there is a need to revamp its centralized procurement pattern and dissemination of drugs to various public health systems in Tamil Nadu. By doing this, it can avoid the high-cost private medicines being promoted even by government doctors, and truly make the public health system successful and a top model in this country.
Lymphoepithelial Cyst of the Parotid Gland Revealing an HIV Infection: A Pediatric Case Report
Authors: H Lhajoui , S Salam , H Safieddine , H Guezri , D Laoudiyi , K Chbani , L Ouzidane
Published: April 2022

Benign lymphoepithelial cyst is an uncommon lesion that usually occurs in the parotid gland or lateral cervical area, including the lymph nodes. In adults, It often reveals an HIV infection. Very few cases in children are reported in the literature. We report the case of a girl, aged 7 years, who consulted for bilateral parotid swelling. Parotid ultrasound and MRI revealed multilocular cystic lesions of both parotids suggestive of lymphoepithelial cysts, who had objectified multiloculate cystic lesions in both parotid. Confirmed by anatomopathological study of the superficial parotidectomy part. The search for anti-HIV-1 and anti-HIV-2 antibodies requested postoperatively came back positive. The patient was referred for care and follow-up in a specialized service.
Pulmonary Involvement in TAKAYASU Disease: From Medical Treatment to Surgery? A Case Report and Review of the Literature
Authors: A Bachar , A Marion , A Karimou , R Diatta , H Dib , Z Nadhil , S Moughil , A Bensouda , N Fellat , R Fellat
Published: April 2022

Background: Takayasu disease is a nonspecific inflammatory arteritis occurring in young people and affecting large arteries. Pulmonary involvement is well documented during the course of the disease but may pose a problem of diagnostic delay. Case Description: We report a case of pulmonary artery involvement following exertional dyspnea in a context of fever with arthralgia revealing Takayasu disease and we will detail the different cardiovascular and pulmonary manifestations of this disease. Conclusion: Takayasu arteritis (TA) is a rare disease that commonly affects women in their second or third decade. The manifestations are highly polymorphic, ranging from asymptomatic presentations to catastrophic neurological presentations. Pulmonary involvement may be a challenge for diagnosis.
Ultrasonic and Microwave Co-Extraction Optimization of Polysaccharide of Portulaca oleracea L. Technology and its Effect on Ulcerative Colitis
Authors: Liu Yu-Peng , Qi Xin , Ma Yi-xuan , zhou Li-jun , Yang Yang , Kong Sheng-nan , Liu Meng-zhen , Zhao Rui , Jia Gui-yan
Published: April 2022

The extraction conditions of polysaccharides from Portulaca oleracea L.（POP） were optimized and its effects on the colonic mucosa of mice with ulcerative colitis were studied. In this study, POP were extracted by ultrasonic and microwave synergism. The extraction process of POP was optimized by a single factor experiment and orthogonal design. HE staining was used to evaluate the pathological changes of colon tissues in mice. The results showed that the optimal extraction conditions were as follows: extraction time was 550 s, microwave power was 40 W, solid-liquid ratio (W/V) was 1:35, and extraction times were 3. Under these conditions, the extraction rate of POP was 3.80%. POP could improve the disease state of UC mice, and the high dose group could significantly reduce the DAI index. The results of the HE experiment showed that POP could reduce inflammatory infiltration and tissue damage of the colon in UC mice. This study provided a theoretical basis for the preparation of POP and its clinical application in the treatment of ulcerative colitis.
Small Duct Primary Sclerosing Cholangitis Ducts: Review and a Case Report
Authors: N’khaili Asmaa , Semlali Riad , Chakor Fatima Ezzahra , Aouroud Meryem , Errami Adil Ait , Oubaha Sofia , Zouhour Zouhour , Samlani Samlani , Krati Khadija
Published: April 2022

Primary sclerosing cholangitis is a rare disease characterized by inflammation, fibrosis, and narrowing of the intrahepatic or extrahepatic bile ducts .Small bile duct PSC(SDPSC) is a subtype of PSC, the prevalence of which is estimated to be around 10% of all CSPs. We report the case of a patient 36 years old, admitted for generalized mucocutaneous jaundice and cholestasis, the etiology was not determined according to the assessments carried out, The MR cholangiography did not reveal any abnormalities explaining the cholestasis, the diagnosis of CSP was made according to the liver histology.
Reconstruction of Post-Burn Flexion Contractures of the Knee Joint with Perforator plus Fasciocutaneous Flaps
Authors: Maitra Dr. Jayabrata , Sethia Dr. Saurav , Chilbule Dr. Priyanka
Published: April 2022

A post-burn flexion contracture of the knee joint is a disabling condition which interferes with an upright posture and a bipedal locomotion. Islanded perforator flaps have been used to resurface the tissue defect which is produced as a result of the contracture release. Despite their various advantages, they are limited by an increased tendency to undergo venous congestion. Perforator-plus flaps can be used to overcome this limitation, while retaining the merits of the islanded perforator flaps.Fifty four patients with post flame burn flexion contractures of the knee joints underwent surgical releases and coverages by various local fasciocutaneous perforator-plus flaps. The patients were followed up for 6 months and the various aspects of the functional and the aesthetic rehabilitations were assessed. All the local fasciocutaneous perforator-plus flaps resurfaced the tissue defect over popliteal fossa with good colour and texture match and maintenance of the contour. None of the flaps had any significant early or delayed complications which necessitated reoperations. All the patients were satisfied with the functional and aesthetic outcomes. Local fasciocutaneous perforator-plus flaps can be considered as one of the primary treatment modalities for the surgical release and reconstruction of post burn flexion contractures of the knee.
Sinonasal Schwannoma: Retrospective Review of Cases from 1997-2016 at A Tertiary Referral Centre
Authors: YK Bobby Lee , JCE Ooi , BS Gendeh , K Jeevaratnam
Published: April 2022

Sinonasal schwannomas (SNS) are benign neoplasms of peripheral nerve sheaths within sinonasal cavities and little is known about them. We aim to expand current literature by analysing all cases of SNS at the National University of Malaysia Medical Centre (UKMMC). There were five females and one male in this study. Mean age was 52.3±2.1 years (range 42-75). The mean tumour size was 3.6cm±0.1 (range 1.50-5.90cm). Tumours originated from outside the sinonasal cavities (n=4) and inside (n=2). Extension was present in five patients. The sinonasal cavity most frequently involved is the maxillary sinus (n=3). Clinical presentation corresponded to site of involvement with facial numbness being the most common presentation. All histopathologically diagnosed cases showed regions of Antoni A, Antoni B, Verocay Bodies and immunoreactivity with S100 protein. Four patients underwent Functional Endoscopic Sinus Surgery (FESS). The presentation of SNS corresponds to their site. Site of involvement is more informative than the site of origin. Endoscopy, CT scans and MRIs are helpful in facilitating an accurate diagnosis. SNS show specific histopathological findings and its main treatment is FESS.
Social Repercussions of Labial-Alveolar-Palatal Clefts in African
Authors: A Coulibaly , S Maïga A. , D Sow , Y Sidibé , I Kansaye , A Salami , M Traoré , R Koné , O Koita , B Ba , S Diop , H Traoré
Published: April 2022

Labial-alveolar-palatal clefts (LAPC) remain a wide spread congenital malformation throughout the world, the psychological impact of its diagnosis notification whether it is antenatal or postnatal period, could lead to emotional upheaval and vulnerability in parents. The objective of this work was to describe the impact of labial-alveolar-palatal clefts on the social behaviors of parents of children suffered from this malformation in our context. This was a descriptive cross-sectional study conducted in Mali from March 2020 to February 2021 and involved mothers of children with labial-alveolar-palatal clefts who agreed to participate in the study. The sample consisted of 60 cases, The mean age of the patients was 7 years and 8 months with a standard deviation of 5.85, The male sex accounted for 68% of cases with a sex ratio of 2.15, The unilateral labial-alveolar cleft was the most met with 55% of cases. Obstetrical ultrasound made the diagnosis in two mothers, The announcement of the malformation was made with tact and respect in 52 cases, The majority of the parents (58 cases) decided to look after their child. Fourteen mothers reported a negative impact on their household activities, In 39.4 per cent of the cases, the respondents stated that they felt responsible for the occurrence of the malformation and did not wish to have a child afterwards for fear of reliving this experience. This study made possible to highlight particular experiences and parenthood during the birth of a flap-bearing child.
Outcome of Intraarticular Steroid Injection and Physical Therapy in Osteoarthritic Knees: A Study on Tertiary Hospital in Bangladesh
Authors: Uddin Dr. M. Sharif , Parvin Dr. Shahana
Published: April 2022

Introduction: An estimated 30% of all general follow-up are due to osteoarthritis (OA). For decades, medical experts have used intraarticular (IA) corticosteroid injections to treat the pain and inflammation associated with osteoarthritis (OA). Objective: To evaluate the patient's functional improvement and clinical result, Evaluations of Intraarticular Steroid Injection Therapy in Osteoarthritis Knee were conducted. Methods: A prospective interventional non-randomized clinical study was conducted in the Department of Orthopaedic surgery, Rajshahi Medical College & Hospital, Bangladesh, from June 2019 to December 2020. A total number (n=54) of patients between 35 and 75 years with knee discomfort for at least three months with radiographic evidence of primary osteoarthritis, male or female, were included in the study. Then, they were split into A and B groups. They had 27 patients in each group, with each group being assigned a random number. There were 6 weeks of follow-up in both groups of patients. Results: 9 (33.3%) were male in group A, and 18 (66.7%) were female. In group B, 10 (37.0%) were male and 18 (63.0%) were female. The mean visual analogue scale (VAS) in group A and group B during pre-treatment were 6.22±1.60 and 7.15±1.56, respectively. The mean age of patients in groups A and B were 52.33±9.62 years and 52.29±9.67 years, respectively. The mean range of motion (ROM) during pre-treatment in group A and group B were 117.33±13.05 and 112.37±19.01, respectively. Meantime taken to walk 50 feet during pre-treatment in group A and group B were 18.22±2.39 and 18.81±2.13 minutes, respectively. After treatment in both groups, visual analogue scale (VAS), range of motion (ROM), time taken to walk 50 feet and range of motion (ROM) gradually increased, which were statistically significant. Conclusion: Steroid injection remains a regular feature in the management of osteoarthritis, particularly osteoarthritis of the knee, despite the lack of strong, ...............
Varicose Vein Stripping with Perforator Ligation Combined With Skin Grafting For Treatment of Venous Ulcers
Authors: T Dr. Narayanswamy , Mali Dr. Chethan , Baig Dr. Mohammed Daanish Subhan
Published: April 2022

Objective: To demonstrate the possibility of combining two procedures, GSV stripping with perforator ligation for varicose veins and skin grafting, to treat patients with venous ulcers related to reflux in saphenous vein. Combined procedure give early better disease free life and reduces ulcer related morbidity, socio economic burden, heath care burden. Methods: A total of 30 patients were treated during the study period of which of which 22 were male and 08 were females. Among 30 patients 26 had unilateral and 4 had bilateral ulcer. Ulcers were associated with concomitant reflux of the great saphenous vein. All 30 patients underwent GSV stripping with perforator ligation and split skin grafting in same sitting of surgery. The strategy employed began by harvesting skin from the donor area from the same limb. Great saphenous vein ligation with perforator ligation was done and skin graft placed over the varicose ulcer in the same sitting of surgery. Results: In all cases there was improvement of ulcer-related symptoms and healing of the lesion. In 28 cases we achieved full skin grafting viability. In 2 cases there was graft failure due to infection. Conclusion: This combination of procedures is a valid option, with the potential to provide quicker and less expensive treatment. Combined procedure give early better disease free life.
Indications of Selling Loss of Hotel Business Personnel in Badung Regency during the COVID-19 Pandemic
Authors: Putra Komang Satria Wibawa , Permana Gusi Putu Lestara
Published: April 2022

Predatory pricing is the action of a company setting prices below production costs with the intention of getting rid of competitors. Business actors are prohibited from supplying goods and or services by selling at a loss or setting a very low price with the intention of getting rid of their competitors in the relevant market so that it can result in monopolistic practices and or unfair competition, this is stated in Article 20 of the Anti-Monopoly Law. The purpose of this study is to examine and analyze the selling price set by several hotel business actors in Badung Regency during the Covid-19 Pandemic based on Article 20 of the Anti-Monopoly Law. There are indications as well as some hotel business actors in Badung Regency. This type of research is a type of empirical juridical research based on legal rules in examining existing social problems or facts and is associated with its implementation in society. By using 3 kinds of legal materials, primary, in the form of facts that occur in the field, secondary, in the form of anti-Monopoly Laws and other regulations, and tertiary, legal materials that support and explain primary and secondary legal materials. They practice selling at a loss by decreasing the selling price of hotel rooms, which can reach 60% of the normal price, resulting in unhealthy business competition during the Covid-19 Pandemic. In addition, there is a legal or regulatory vacuum related to the lowest standard selling price for hotel room occupancy rates which can result in the absence of legal certainty among hotel business actors and can make it difficult for supervision that the government can carry out.