bluuebunny/crossref_metadata_2025 huggingface dataset:
Construction of a VPN System for Remote Programming and Monitoring of Environmental Parameters for Serving Plant Production in Greenhouses
Authors: Dieu Nguyen Van , Ngo Duong Tri
Published: June 2019

This article introduces a virtual private network (VPN) system deployed in a 70m2 operator station and greenhouse at Vietnam National University of Agriculture. The VPN system was not limited by geographical distance and allowed for remote monitoring of environmental parameters, viz. light (10-16000lux), soil moisture (20-100%), temperature (20-60oC), and ambient humidity (30-90%) with tolerances of ± 5% of the set/measured values. The signals from the sensor system were recorded with a sampling time of 6 seconds. The designed interface made it easy for Vietnamese users. The system was initially established, and tested successfully with Gerbera in the greenhouse. The VPN system allowed for remote programming, stable operation, and no loss of data during the signal collecting process, and allowed users to fully and quickly react when the system crashed or when the user needed to upgrade or maintain the greenhouse system.
Asymmetry of jet streams formed under nonlinear geostrophic adjustment in shallow water
Authors: Kalashnik M. V.
Published: June 2019

The process of geostrophic adjustment in a rotating layer of shallow water is considered. For initial distributions of the fluid depth in the form of a step and a localized rectangle, this process results in the formation of an isolated jet stream and a system of two counter jet streams, respectively. In this paper, the features of these flows structure, related to the nonlinearity of the adjustment process, are studied. The main feature for an isolated jet stream is the horizontal asymmetry of its velocity profile. For a system of two opposing flows, a mirror asymmetry is characteristic, which is caused by the dependence on the sign of the amplitude of the initial disturbance of depth. The velocity of flows with a negative sign (depression) always exceeds the velocity with a positive sign (elevation).
Dynamics of organic matter in bottom sediments on the cut Razdol'naya River-Amur Bay (Sea of Japan)
Authors: Polyakov D. M. , Maryash A. A. , Khodoeenko N. D.
Published: June 2019

Contents of Corg, as well as humine (HA) and fulvic (FA) acids, have been investigated within soil, riverine and marine sediments along the profile, joining the Razdolnaya River and the Amur Bay. The elevated contents of the Corg. have been elucidated within soil deposits against to riverine and marine sediments, and it is associated with peatlands. There has been noted, that the increase of HA contents against FA ones has been taken place just within those sediments, that has been corresponded the initial period of the water mixing, and it has been connected with flocculation. There have been established the riverine sediments with extended contents of FA, Fe, Mn, and it has testified about the active processes of flocculation and Fe-Mn oxihydroxides forming. It has been noted, that the soil sediments have contained more humiphicated organic matter than marine ones. To a great extent, marine sediments have contained not biogeochemically processed organic matter.
Spatial variability of phytoplankton primary production characteristics in the North Atlantic in summer 2013
Authors: Demidov A. B. , Mosharov S. A. , Gagarin V. I. , Gladyshev S. V. , Dukhova L. A. , Romanova N. D. , Mosharova I. V.
Published: June 2019

Spatial variability of phytoplankton primary production characteristics has been studied along the transects between Shetland Islands and Iceland (transect I) and along 59.5° N (transect II) from 30 June to 16 July 2013. It has been shown that surface chlorophyll a concentration (Chl0) varied more than two order of magnitude from 0.07 to 6.67 mg/m3 (transect I) and from 0.02 to 3.63 mg/m3 (transect II). Water column integrated primary production (IPP) changed by a factor of 3.8 from 273 to 1040 and by a factor of 5.6 from 68 to 379 mgC/m2 per day along transects I and II, respectively. It has been established that spatial variability of Chl0 and IPP was consistent with distribution of the main surface flows and thermohaline fronts. That conclusion was made on the basis of reliable positive correlation between Chl0 and the zonal potential temperature gradient (R = 0.43, p < 0.01, N = 65). Phytoplankton assimilation activity along transect II depends on nutrients concentration. That conclusion was confirmed by reliable positive correlation between optimum chlorophyll specific carbon fixation rate (Pbopt) and phosphate concentration (R = 0.58, p < 0.05, N = 76) and between Pbopt and dissolved silica (R = 0.51, p < 0.05, N = 76).
Complex research during the 33-rd cruise of research vessel “Akademik Nikolaj Strakhov”
Authors: Sivkov V. V. , Peyve A. A. , Bubnova E. S. , Akhmedzyanov V. R. , Kreehik V. A. , Sukhih E. A.
Published: June 2019

The 33rd cruise of the R/V “Akademik Nikolaj Strakhov” was in the Atlantic Ocean and the Baltic Sea, and included a complex of geological, hydrological and hydrochemical works. According to the results of a multibeam echo sounder survey of the bottom, digital models of bottom landscapes were constructed. Using the dredging method, new geological samples were obtained, and the values of geothermal flows in the Atlantic Ocean were measured.
In memory of A.S. Selivanov
Authors: «Earth observation and remote Sensing» Board of the journal
Published: June 2019

In memory of A.S. Selivanov
RETRACTED: EDAS method for multiple criteria group decision making under 2-tuple linguistic neutrosophic environment
Authors: Wang Ping , Wang Jie , Wei Guiwu
Published: June 2019

This article has been retracted. A retraction notice can be found at https://doi.org/10.3233/JIFS-219433.
Impulse Noise Parameter Assessment in a Batch Radio Channel
Authors: Bekkiev A. Yu. , Makoviy V. A.
Published: June 2019

Modern radio communication means to provide safe data transmission due to adapting radio channel to the actual noise environment. It is impossible to conduct proper comparative tests on various radio stations offered by manufacturers and to compare objectively the results obtained in field without actual signal parameters and noise environment instrument inspection at the reception point. The paper considers tactical level radio communications system operation when jammed with powerful impulse noise of various nature. It suggests a device enabling to assess the main parameters of impulse noise, namely desired signal and additive noise mixture envelope effective value, impulse noise envelope effective value, impulse noise duty factor. To provide measurement independence from a specific realization of a decoder it is suggested to use the envelope of a signal received by a radio station. The developed device uses standard radio channel data batches as measuring signals and does not require changing radio channel or radio network algorithms and timing charts. A method to assess the effective value of desired signal envelope and additive noise mean-square value when the received signal involves impulse noise is suggested. The paper demonstrates that valid assessment of desired signal and additive noise mixture is possible in case of setting aside selection values affected by impulse noise. A device separating symbols affected by impulse noise from those that are not affected is suggested. Formulas that allow synthesizing the device operation algorithms are obtained. The structure chart of the measurer is developed; the algorithms used to assess measured parameters are given.
The Stand for Research of Positional-Sensitive Photosensor
Authors: Chukita V. I. , Senokosov E. A. , Feshchenko V. S.
Published: June 2019

The paper considers position-sensitive photodetectors (PSP), which are designed to detect the source of electromagnetic radiation in the optical range and determine the coordinates of the irradiated area in real time, as well as to track moving optical objects. In particular, data are presented on photodetectors based on photosensitive epitaxial CdSe/mica layers with an unconventional layout and switching of electrical contacts. The output signal of such PSP is the transverse potential difference that appears between its two contacts after exposure of one of the areas of the photodetector. These PSPs can be an alternative or competition to existing photocells due to high accuracy, speed, ease of manufacture and low cost. But there are significant obstacles for their wide application. First, it is an analog type of output signal, which prevents its further processing. And, second, it is difficult to calibrate “manually” a newly made photosensor: it takes a long time associated with the accumulation and processing of large amounts of data. The introduction of computer technology and the creation of an information-measuring system allow us to process the output signals of such photodetectors with high accuracy and speed in  real time. To solve this problem we have developed a stand for the study of position-sensitive photodetectors, which is presented in this paper. This stand allows digitizing the signal received from the photodetector, in real time, with high accuracy to determine the coordinates of the irradiated area on the photodetector and explore its characteristics such as the specified value of the dark current of the photodetector, light current at a certain illumination, and output voltage. At this stand, position-sensitive photodetectors based on the CdS/mica system were studied. It is shown that the characteristics and parameters of photoreceivers measured on this stand coincide with theoretical ones, within the error limits. Recommendations on the use of the standare given.
Stochastic and Percolating Models of Blocking Computer Networks Dynamics during Distribution of Epidemics of Evolutionary Computer Viruses
Authors: Lesko S. A. , Alyoshkin A. S. , Filatov V. V.
Published: June 2019

The paper presents a complex model of the dynamics of virus epidemies propagation in computer networks, based on topological properties of computer networks and mechanisms of the viruses spread. On one hand, this model is based on the use of percolation theory methods, which makes it possible to determine such structural-information characteristics of networks as the dependence of the percolation threshold on the average number of connections per one node (network density). On the other hand, the dynamic processes of stochastic propagation in computer networks of evolving viruses are observed when anti-virus programs become outdated and postponed. The paper discusses the concept of percolation threshold, provides an equation for the dependence of the percolation threshold of a network on its density obtained by analyzing numerical simulation data. The dynamics of virus epidemies were studied through two approaches. The first one is based on the description of transition diagrams between states of nodes, after which a system of kinetic differential equations for the virus epidemies is constructed. The second is based on considering the probabilities of transitions between possible states of the entire network. A second-order differential equation is obtained in this article, and a boundary value problem is formulated. Its solution describes the dependence of the network blocking probability on the blocking probability of an individual node. The solution also makes it possible to estimate the time required to reach the percolation threshold. The model incorporates the evolutionary properties of viruses: previously immunized or disinfected nodes can be infected again after a certain time interval. Besides, the model incorporates a lag of the anti-virus protection. Analysis of the solutions obtained for the models created shows the possibility of various modes of virus propagation. Moreover, with some sets of values of differential equation coefficients, an oscillating and almost periodic nature of virus epidemies is observed, which largely coincides with real observations.
Dynamic Programming as a Method of Spline Approximation in the CAD Systems of Linear Constructions
Authors: Karpov D. A. , Struchenkov V. I.
Published: June 2019

Under study is a problem of the line structure routing of roads, railways and other linear constructions. Designing a trace plan and longitudinal profile are considered as non-linear programming tasks. Since the number of elements of the plan and the longitudinal profile is not known, the problem is solved in three stages. First, a search is performed for a polyline consisting of short elements. On the second stage it is used to determine the initial approximation of the desired line, which is optimized at the last stage. The required line consists of a given type elements and it is a spline with a number of features:- In contrast to the polynomial elements considered in the theory of splines, when designing roads unknown spline is a sequence of elements: straight, clothoid, circle, clothoid, straight and so on.- In this task, the spline does not have to be a single-valued function.- The parameters of the elements of the desired spline must satisfy the constraints in the form of inequalities.These features of the task do not allow the use of non-linear programming methods to solve it. Converting a broken line to a spline is carried out using dynamic programming. For this purpose a special formalization of this task is proposed. A new algorithm of dynamic programming is given. The result is used as an initial approximation to optimize the parameters of the spline using a previously developed non-linear programming program.
高中语文教学中渗透德育教育的途径思路分析
Authors: 徐 武平
Published: June 2019

随着我国教育改革的不断深入与发展，德育教育已由传统教育中次要目标向现代化教育中的主要目标进行转移，大多数学校均将德育教育视作学校教育教学工作的主要内容，同时也是时下高中素质教育的一个重要目标。从落实语文科目素质教育要求的角度上来谈，如何在高中语文教学活动之中渗透德育教育，是目前高中语文教师所亟需思考的问题。本文对如何在高中语文教育教学活动之中渗透德育教育的途径及思路进行了简要分析，从德育教育于高中语文教学的意义谈起，陈述了目前高中语文德育教育之中尚存的问题，并提出了针对性的德育教育渗透途径与教育思路，希望能够对广大高中语文教育工作者以一定的帮助。
土木类专业人才沟通能力培养体系的研究与实践
Authors: 蒋 玉飞 , 刘 杞威 , 李 倩
Published: June 2019

随着建筑人才市场对专业从业人员技术交流能力要求的不提高，高校对土木类专业学生沟通能力的培养也日益关注。文章通过四川大学锦江学院多年来在土木类专业学生沟通能力培养中的研究与实践，对土木类专业学生沟通能力培养体系和培养路径进行了论述。
“一带一路”背景下重庆民办高校教育国际化发展研究
Authors: 夏 冬梅 , 陈 维
Published: June 2019

习近平主席先后在2013年9月与10月将建设“新丝绸之路经济带”和“21世纪海上丝绸之路”的战略构想提出，并将其视为“一带一路”的合作理念或倡议。倡议必定会增强西部地区的对外开放成都，从而进一步影响重庆地区教育国际化的深层次改革。而面对重庆地区的民办高校国际化发展不均衡等问题，本文试论述重庆地区国际化与民办高等教育发展之间的联系，进一步提出民办高校国际化发展的策略。
基于士官院校电工技术课程的研究与思考
Authors: 黄 艳艳 , 侯 慧娜
Published: June 2019

电工技术是士官高等职业技术教育各专业任职基础的主干课程,也是一门抽象难懂的课程,对学员后续的学习有着重要的作用。本文针对电工技术在教学中出现的问题,通过大量的调查研究发现想要提高士官学员学习本门课的兴趣,提高实践能力,教员应该改变原有的教学方法,整合教学内容,优化考核模式,提高自身素质等方面入手。
旧社区住宅空间适老性改造及陈设应用研究——以湖南省某厂矿生活区住宅为例
Authors: 贾 思怡
Published: June 2019

基于对于湖南省株洲市某旧社区住宅调研,发现该类住宅空间适老性问题非常突出,继续改善。为此本论文探讨如何简便、实惠、快捷提高老年人居住需求满意度的方法,提出与适老性陈设品结合对旧社区住宅进行改造的思路。
高职学生职业技能与职业精神的有机结合的相关思考
Authors: 王 米雪 , 圣 志存 , 岳 丽佳 , 吴 萌 , 张 继玲
Published: June 2019

在社会经济不断发展的大背景下,现代企业已经不仅仅通过职业技能这个单一方面来衡量一个人才,而是设置了职业技能与职业精神的双重标准。在我国现代教育体系当中,高职院校的地位正在不断上升,成为了为国家建设培养实践型人才的主要平台。要想充分适应社会发展的步伐,培养出更多符合用人单位要求的优秀毕业生,高职院校就必须针对培养计划和目标这两个方面做出改革。对培养学生的职业技能与职业精神实施“两手抓”。本文就高职学生职业技能与职业精神的有机结合路径展开了一系列的思考。
基于职业汉语能力培养的职业汉语教学改革
Authors: 杜 丽丽
Published: June 2019

本文主要通过文献资料法对基于职业汉语能力培养的职业汉语教学改革进行研究,首先分析了提升职业汉语能力的重要意义,然后对海南省职业汉语课程教学现状做进一步分析,发现目前高职院校职业汉语课程出现的问题主要有：职业汉语课程处于边缘化、相关教师知识结构单一、学生文化基础差、职业汉语课程内容与职业汉语能力不契合,结合实际提出解决策略：准确把握职业汉语课程目标、围绕职业汉语能力开发兼具听说读写的职业汉语教材、运用项目式教学激发学生学习主动性、采用科学和合理的考核方式。
“互联网+”时代下中职学校创业教育实践模式探索——以洛阳铁路信息工程学校为例
Authors: 王 楠
Published: June 2019

随着技术的进步,“互联网+”已经融入到生活的各个层面,本文紧密结合时代特征,从中职学校学生的创业实践教育入手,以本校为例,分别从工科类专业和经管类专业两个方面探索了适合我校发展的创业教育实践模式,为中职学校创业实践教育提供了一定的现实意义。
论教练技术在高校辅导员学生工作中的应用研究
Authors: 温 裕峰
Published: June 2019

教练技术是教练者通过教练式提问,帮助被教练者探索自我,激发个人无限潜能,促使自己去寻求资源,找到解决问题的技术。本文通过一名辅导员与学生沟通的案例阐述如何将教练技术应用在学生工作中,关注学生的内在需求,促使学生自我反思,帮助学生实现自我成长,进而改善学生管理工作的方式,提高学生工作的有效性,扩宽辅导员工作的模式。
心态积极与行为颓废——当代大学生中“积极废人”群体的现象解读
Authors: 刘 柯婷
Published: June 2019

“积极废人”是一个网络流行词,它指那些爱给自己树目标,立标签,但却永远做不到的人。这个词汇的产生和使用主要表现在80后、90后、甚至是00后的年轻人身上。这个现象中的群体在日常生活中心态积极向上,行动却颓废不为。这个组合词生动形象地概括了大学生某个群体的心理状态和行为模式的矛盾作用下产生的结果,传递着他们的自嘲信息,鲜明地反映了当代大学生的性格特点,形成了一种独特的社会景观。
基于社会主义核心价值观在高职院校思想政治教育中的探讨
Authors: 肖 盛
Published: June 2019

随着我国社会主义现代化道路的不断发展,教育行业的地位也逐渐开始提高,高职院校关于思想政治教育的要求也越来越严厉。社会主义核心价值观对高职院校进行思想政治教育工作是必不可少的,具有重要意义。而目我国很多高职院校的思想政治教育都存在一些问题,为了有效解决这些问题,需要高职院校融入社会主义核心价值观的思想。针对如何基于社会主义核心价值观进行高职院校的思想政治教育,本文进行了简单的研究和分析,并提出了相关的看法。
浅谈微课制作的几种方法
Authors: 马 玉桂
Published: June 2019

随着时代的发展,微课作为一种新的学习资源形式,已经成为了课堂教学和课后辅导的重要组成部分。我们一线教师对微课的制作也产生了浓厚的兴趣和热情,微课的制作,不仅仅能够提升教师的信息技能,也能提高教师专业综合素养。那么,怎么进行微课的制作呢？本文围绕常用的几种微课的制作方法来探讨微课。
高职院校校内实训基地管理及运行机制研究
Authors: 彭 绮伦
Published: June 2019

高职院校校内实训基地目前所普遍存在的问题是效率低下,主要表现在实训基地建设缺乏先进性以及系统性,实训项目设置不科学,实训基地管理方式不合理等。要对高职院校内实训基地的管理以及运行机制实行创新,保证充分发挥高职院校实训基地的功能性,以此提高校内实训基地的建设完善程度。本文主要探讨高职院校内实训基地管理以及与运行机制,并提出几点建议。
基于现代教育技术环境下高职《机械制图》课程教学模式的相关分析
Authors: 冯 琴
Published: June 2019

《机械制图》是机械工程的语言,涉及到机械的设计、制造、维修等多方面,对将来从事机械行业的学生来说非常重要。但是由于传统的高职《机械制图》课程教学方法比较单一、落后,而且教学课程没有与实际的工程操作练习起来,让学习理解起来非常困难,导致学生失去学习的积极性。而基于现代教育技术环境下高职《机械制图》课程教学模式的引入可以有效改变这种教学现状,大大提高教学质量和学生的学习效率。因此,本文就对基于现代教育技术环境下高职《机械制图》课程教学模式做了一些相关分析。
基于“诊改”的高职院校校本数据平台框架体系搭建研究
Authors: 徐 娟
Published: June 2019

本文从高校信息化存在的问题出发,提出建设基于“诊改”的校本数据平台的重要意义,在深入思考如何搭建校本数据平台的基础上搭建了校本数据平台的框架体系并对校本数据平台各模块功能进行简单介绍。最后对如何更加合理利用校本数据平台、进一步发挥其价值提出了思考。
在美术课堂中放飞快乐
Authors: 陈 琳
Published: June 2019

成功的美术教育教学应该让学生有意识地参与课堂教学,让学生集中注意力并对所学内容感兴趣。让学生体验艺术在欣赏和创造中带来的快乐,让孩子们用画笔自由表达情感,展现各自的内心世界,提高审美能力。通过愉快的教学,教师可以让学生在艺术课堂上感到快乐。
高校社团管理与改革问题探究
Authors: 葛 孟瑶
Published: June 2019

基于高校“立德树人”的根本任务,高校社团的管理与改革问题成为了近些年我国高等学校亟待研究和讨论的命题。如何整合资源,搭建合理的社团组织架构,需要进一步完善社团联合会的职能,规范社团的运行模式。
中职钳工项目化教学研究
Authors: 田 义
Published: June 2019

进入新时期后,我国教育教学体制改革日趋深入,对中职教育也提出了更高的要求。传统中职钳工教学模式下,学生的学习兴趣不高,难以有效培养学生的实践能力和创新能力,降低了课堂教学效率,不利于中职人才培养目标的顺利实现。针对这种情况,需要积极引入项目化教学,并结合教学内容与学生的实际情况,合理设计项目化教学实施方案,力争在提升中职钳工教学质量的同时,也能培养学生的动手实践能力和创新能力。
信息焦虑视角下浙江省高职青年教师自我效能感提升对策研究
Authors: 向 科衡
Published: June 2019

高等职业教育的重点是面向企业培养从业就业型工作人才,这与高等职业教育的培养目标相一致,而人才的培养离不开教师的教育。高职院校本身科研项目的运作难度高,投入产出比低,加上不对称的晋升、科研、职称等信息的刺激,使得高职青年教师容易产生信息焦虑,进而降低自我效能感和职业满足感。本文从信息焦虑视角出发,以浙江省高职青年教师为研究主体,分析信息焦虑对高职青年教师自我效能感产生的原因和影响因素,并结合内部环境和外部环境提出高职青年教师自我效能感的提升对策。
全球化战略下跨境企业案例研究与人才培养策略
Authors: 王 杰 , 屠 诗 , 袁 江军 , 卢 静宜
Published: June 2019

当前,在“一带一路”及全球化战略的引导下,越来越多的中国企业走出了国门,走向了非洲、亚洲等海外市场。然而由于国家政治体制、经济发展水平、社会文化制度、法律制度、公司监管环境等方面存在差异,众多企业在开展跨境业务的同时,遇到了众多棘手的问题。本研究课题从中国跨国企业国际化扩张过程中面临的治理难题出发,立足不同国家间制度距离等客观情景,通过分析典型的跨境企业并购案例,揭示其内在的规律,提出相应的跨境人才培养策略。
创新创业导向的专业课程体验式教学设计——以高职印刷媒体技术专业为例
Authors: 赵 韵姬 , 党 亚男 , 李 伟
Published: June 2019

如何通过实践体验促进学生掌握专业相关知识与技能,培养创新创业意识,使其更好适应实际工作岗位,是如今高职教育的重要命题。本文对高职印刷技术专业课程进行了创新创业视角下的体验式教学设计,并通过具体教学流程的实施来探讨该模式应用的有效性。
翻转课堂在大学体育教学中的应用探索
Authors: 张 玉玺
Published: June 2019

翻转课堂是指调整教学模式,转化师生角色,改善课堂时间分配的一种教学模式。翻转课堂以合作探究为核心,以强化学生综合素养为目标,是推动教育教学体制深化变革的重要举措。本文简要介绍了翻转课堂的基本概念,综合论述了推广翻转课堂的实际意义,并围绕翻转课堂在大学体育教学中的实践应用展开系统探究。
Introduction: the use of corpora for language teaching and learning
Authors: Casas-Pedrosa Antonio Vicente , Fernández Domínguez Jesús , Alcaraz Sintes Alejandro
Published: June 2019

This paper aims at contextualizing and presenting the first volume of the journal Research in Corpus Linguistics and is, therefore, divided into two main parts. First of all, it provides an introduction to the field ofcorpus linguistics and its increasingly relevant role in language teaching and learning. Secondly, it briefly introduces and discusses the six articles of the volume. Stemming from oral presentations delivered at the 4th International Conference on Corpus Linguistics (CILC2012, Jaén, Spain), these articles have a number of features in common. They all make extensive use of corpora and at the same time deal with language teachingand language learning, the underlying assumption being that a genuine and mutually beneficial connection can be established between teaching and research. For this reason, each of them constitutes an illustrative sample of how different corpora can be exploited for different research purposes.
Lexicalization and Spanish derivational morphology
Authors: Benavides Carlos
Published: June 2019

In this study lexicalization refers to derivation where an idiosyncratic component of meaning has been acquired. Being non-compositional, lexicalized items are usually considered irregular. In accordance with an emerging view that irregularity should take a place as one of the central issues in linguistic theory, this article deals with lexicalized derivatives in Spanish within the framework provided by the dual-route model. On the basis of intuitive speculation and an exploratory search of a Spanish corpus, the hypothesis was formulated that a significant majority of derivatives in Spanish are compositional; therefore, lexicalization is a secondary process in Spanish word formation. A corpus study comparing results from two large Spanish corpora was conducted to test the hypothesis. The results, based on an analysis of over 10,000 derivatives confirm the hypothesis, supporting the author’s intuitions and providing additional support for the dual-route model. In addition, the corpus findings suggest that metaphor in Spanish derivation is not as common as may previously have been thought.
Modeling for Copper Ablation by Ultrashort Laser Bursts-Train
Authors: Abdelmalek Ahmed , Bedrane Zeyneb , Amara El-Hachemi
Published: June 2019

Ablation of copper using multipulse femtosecond laser irradiation with an 800 nm wavelength and 900-fs pulse duration is investigated theoretically using a dynamic tow temperature model. Our results show that the irradiation of a metal film by burst femtosecond laser with a separation time between pulses less than the thermal relaxation time can dramatically enhance the irradiated focal volume without a significant dissipation of the energy inside the material. We demonstrate the advantage of burst irradiation at low fluence where the cooper can be ablated below single ablation threshold. We also suggest that at high fluence, irradiation with a burst-train may give rise to a cleaner ablation than with a pulse-train.
Water Framework Directive and Modelling Using PEGOPERA Simulation Software
Authors: Everbecq Etienne , Grard Aline , Magermans Pol , Deliège Jean-François
Published: June 2019

The Water Framework Directive 2000/60/EC (WFD) established a framework for community action in the field of water policy. To implement the WFD, the competent authorities for watershed management should use modelling techniques to establish, for example, the pressure/impacts relationship. The PegOpera modelling tool (composed of the water quality model Pegase and a friendly Graphical User Interface), has been developed in order to be compliant with the requirements of the WFD. Pegase is a physicochemical model describing the behaviour of whole river systems, at various scales, from tens to tens of thousands km². The specificity of the model is its ability to work at a high spatial resolution not only for small river basins (water body level), but also for large drainage networks. Already used by several basin management competent authorities, the PegOpera modelling tool proved to be an efficient tool for helping in surface water management from local up to the international district level and is therefore an operational numerical tool for WFD implementation.
The anxiolytic and analgesic effects of melatonin: a study protocol for a randomized, double-blind, placebo-controlled study
Authors: Kollerup Madsen Bennedikte , Zetner Dennis , Andersen Lars Peter Kloster , Rosenberg Jacob
Published: June 2019

Anxiety and pain are both significant clinical challenges following surgery. Melatonin has been demonstrated to have both anxiolytic and analgesic effects in numerous experimental and clinical studies. This study protocol aims to present the design of a randomized study investigating the anxiolytic and analgesic effects of exogenous melatonin in cosmetic breast augmentation.     The study will be a randomized, double-blind, placebo-controlled trial. Included patients are candidates for primary breast augmentation or replacement of existing implants. Patients receive a standardized general anesthetic and postoperative analgesic regimen. The study medication includes 4 separate doses, containing either 10 mg of melatonin or placebo. Doses are administered orally at 21:00 hours of the night before surgery, 120 minutes before surgery, immediately after surgery in the post-anesthesia care unit, and at 21:00 hours of the night following surgery.      The two primary outcomes are preoperative anxiety, assessed by the State-Trait Anxiety Inventory and pain, measured by an integrated assessment of longitudinally measured pain intensity and opioid consumption. Secondary outcomes are VAS anxiety, and VAS pain, sleep quality, general fatigue and wellbeing.      This study protocol presents in detail the design of a randomized, double-blind, placebo-controlled study investigating the anxiolytic and analgesic effects of repeated doses of exogenous melatonin in patients undergoing cosmetic breast augmentation.
2-Hydroxymelatonin confers tolerance against combined cold and drought stress in tobacco, tomato, and cucumber as a potent anti-stress compound in the evolution of land plants
Authors: Lee Hye-Jung , Back Kyoungwhan
Published: June 2019

Melatonin (M) is an endogenous molecule found ubiquitously in animals and plants that helps maintain various biological functions. Unlike animals, plants preferentially synthesize 2-hydroxymelatonin (2M) over M, but the biological functions of 2M remain largely unknown. Here, we found that exogenous foliar application of 2M conferred tolerance against combined cold and drought stress in tobacco (Nicotiana benthamiana), tomato (Solanum lycopersicum L. cv. Micro-Tom), and cucumber (Cucumis sativus L. cv. Baecdadaki), whereas no such tolerance was observed against these stresses applied individually. Accordingly, endogenous 2M was induced in tobacco and tomato leaves in response to combined stress, whereas M levels remained unchanged in tobacco leaves and decreased in tomato leaves. After challenging tobacco and tomato leaves with prohexadione-calcium, an inhibitor of 2M synthesis, 2M levels decreased and led to hypersensitivity to combined stress. Because the gene encoding 2M is found only in land plants, and is absent in cyanobacteria and algae, we propose that 2M may have evolved as aquatic plants invaded land to overcome the stressors of virgin terrestrial environments, such as cold and drought.
Are melatonin doses employed clinically adequate for melatonin-induced cytoprotection?
Authors: Cardinali Daniel Pedro
Published: June 2019

This review article discusses the special role that melatonin, a molecule with

chronobiotic/cytoprotective properties, may have in prevention and treatment of

the metabolic syndrome (MS), ischemic and non-ischemic cardiovascular diseases

and Alzheimer´s disease (AD). Prevention of these diseases is a major goal for

governmental and non-governmental organizations, and melatonin, an unusual

phylogenetically conserved molecule present in all aerobic organisms, merits

consideration in this respect. In humans, circulating melatonin levels are consistently

reduced in MS, ischemic and non-ischemic cardiovascular diseases and AD, the

potential therapeutic value of melatonin being suggested by a limited number of

clinical trials generally employing melatonin in the 2-5 mg/day range. In

animal model studies of MS, ischemic and non-ischemic cardiovascular diseases

and AD melatonin was very effective to curtail symptomatology. However,

calculations derived from animal studies indicate projected cytoprotective

melatonin doses for humans in the 40-100 mg/day range, doses that are rarely

employed clinically. Hence, controlled studies employing melatonin doses in

this range are urgently needed. Since the pharmaceutical industry is refractive

to support them because of the lack of protective patents for a natural

compound, only the involvement of governmental and non-profit organizations can

achieve that goal. Within this prospect, the off-label use of melatonin is

discussed.
Clock genes and the role of melatonin in cancer cells: an overview
Authors: Chuffa Luiz Gustavo de Almeida , Seiva Fábio Rodrigues Ferreira , Cucielo Maira Smaniotto , Silveira Henrique Spaulonci , Reiter Russel J , Lupi Luiz Antonio
Published: June 2019

Circadian rhythms control most biological processes in every organism and their disruption or an aberrant function in the expression of clock genes are associated with a number of cancers including some hormone-dependent and independent cancers. The processes involved in carcinogenesis and tumor progression are complex, but understanding the daily profiles of the core clock genes and their clock-controlled genes is essential to evaluate specifically the molecular program of the cancer phenotype; this may be helpful in providing a more realistic strategy for both diagnosis and treatment during the course of the disease. Because melatonin production and secretion oscillates rhythmically through the light:dark cycle and is related to the circadian machinery genes (Clock, Bmal1, Periods, and Cryptochromes), its regulatory role on clock genes in cancer cells may bring additional evidence regarding the mechanism(s) by which melatonin is involved. Mechanistically, melatonin acts via proteasome inhibition and sirtuins to indirectly modulate clock genes in cancer; however, melatonin seems to be capable of directly altering the expression of clock genes to affect cancer development. Depending on cancer cell type, melatonin might up or downregulate specific clock genes to control cell cycle, survival, repair mechanisms, etc. In parallel, melatonin exerts pro-apoptotic, anti-proliferative and pro-oxidative effects, metabolic shifting, reduction in neovasculogenesis and inflammation, and restores chemosensitivity of cancer cells. Finally, melatonin improves the life quality of patients. This review focuses on the main functions of melatonin on clock genes, and reviews, from a clinical and experimental standpoint, how melatonin regulates the expression of clock genes in some prevalent cancer types such as breast, prostate, liver, and colon cancers, leukemia and melanoma. We further emphasized possible signaling mechanisms whereby melatonin interferes with clockwork genes and circadian-controlled genes within cancer cells.
Analisa dan Perancangan Sistem Keuangan Tandan Buah Sawit (TBS) pada Koperasi Sumber Rezeki Kampung Rantau
Authors: Hasan Mhd Arief , Rianto Rianto
Published: June 2019

This study aims to analyze the financial system of Bunch Palm Fruit (TBS) in the Cooperative Source Rezeki Kampung Rantau Minas District Siak District. Basically Koperasi Sumber Rezeki is a cooperative that runs a community plantation business but now Sumber Rezeki Cooperative is progressing so that Sumber Rezeki Cooperative opens units such as savings and loan units and fertilizer sales unit. Management of the administrative system to date in the Cooperative Resources Rezeki still done manually with the number of cooperative management is very limited. This leads to slow performance of the cooperative and allows for the mistakes that are not desired by the manager of the cooperative. Therefore, the need for a new system more efficient in reducing the problem of this problem. The system developed is an application of savings and loan, recording, and calculation of the sale of FFB, and the sale of fertilizer. The design of this application is made for the purpose of facilitating the cooperative managers in monitoring the existing finances without having to examine every manual book written by its members.
Aplikasi Pelaporan Aktivitas Siswa kepada Orang Tua Berbasis Web dan SMS Gateway
Authors: Turaina Rifa , Putri Nency Extise , Anwar Novia
Published: June 2019

Good human resources are created thanks to education. In order to have good education resources as expected, parents' control of student behavior in schools is required. In order for student activities in SMK N 1 Kinali can be controlled by parents well, then needed an application that can be used for parents. The purpose of this study is to create user information applications for web-based parents and SMS Gateway. This app can be used to report how many points students do at school to parents. Any difficulties done by students will be used for their parents via SMS Gateway. The design of this application using the technique. And PHP Programming and MySQL database. With this application can help parents to be able to further improve supervision and can also affect student learning.
Sistem Informasi Geografis Pemetaan Lokasi Kandang Peternakan Sapi di Kabupaten Lima Puluh Kota
Authors: Defiariany Defiariany , Putra Ilham Eka , Putra Andreo Permana
Published: June 2019

This research aims to design Geographic Information System mapping of cow shed location in fifty cities district. This system is used to facilitate the Department of Animal Husbandry and Animal Health of West Sumatra Province in managing and categorizing the data location of cattle ranch in Lima Puluh District. In addition, this system can facilitate the agency in preparing reports and delivering information to the cattle cattle location through better media. Given this geographic information system, there will be no duplicate data recording, and all data will be stored neatly in the database so that when needed the data can be retrieved easily.
Sistem Informasi Geografis Jaringan Tiang Listrik dan Trafo Pada PT. PLN (Persero) Rayon Tabing
Authors: Suryani Ade Irma , Aswin Arief Rahmadian , Khabibi Imamul
Published: June 2019

PT. PLN (Persero) Rayon Tabing is a company that serves the distribution of electrical power throughout the customer which is included in the scope of rayon tabing. This streaming system is assisted by a distribution tool that is a transformer. Research conducted at PT. PLN (Persero) Rayon Tabing, found the problems that serve as the basis in the writing of this thesis is Geographic Information System of Electric Pipelines and Trafo. GIS has the ability to provide information and display in map form. Currently the information about the transformer data map obtained is still a manual map, only limited to the image display and location plan without including a database that shows the attributes of each object. Therefore it is necessary to have GIS easily digested and mutually integrated both for personnel involved in PLN party and society. The method used in this research is by interview, observation. GIS is designed using Google Maps API and PHP Programming Language and MySQL Database. By using internet connection, GIS is able to help PLN to find the location of the transformer and the information needed.
Hand, Foot, and Mouth Disease Caused by Coxsackievirus A6: A Preliminary Report from Istanbul
Authors: CEYLAN AYSE N. , TUREL OZDEN , GULTEPE BILGE SUMBUL , INAN ELIF , TURKMEN AYSEL VEHAPOGLU , DOYMAZ MEHMET Z.
Published: June 2019

Hand, foot, and mouth disease (HFMD) is caused by various serotypes of Enterovirus genus. Coxsackievirus A16 (CV-A16) and enterovirus A71 (EV-A71) were known to be the only responsible agents for these epidemics; however, this opinion was challenged after the detection that coxsackievirus A6 (CV-A6) was the responsible species for the outbreak in Finland in 2008. HFMD is frequently seen in Turkey, and no detailed study on its clinical and microbiological epidemiology has previously been reported. The present study addresses this question. Twenty-seven patient samples collected between 2015 and 2017 were included in the study. Typing was conducted by RT-PCR and the sequencing applied directly to patient’s samples and as well as to the viral cultures with pan-enterovirus and serotype-specific primers. The presence of Enterovirus in 12 of 27 HFMD samples was shown with RT-PCR. The causative agent for three of these 12 samples was CV-A16, one of the most frequent two serotypes around the world, and the remaining nine samples was CV-A6. The findings of the study are relevant since it pertains to the molecular epidemiology of HFMD in Turkey, a gateway country where different serotypes might be circulating and transmitted. The findings also support the notion that CV-A6 cases are rising in number, which has caused more severe clinical features and widespread rashes in recent outbreaks.
Evaluation of a Salmonella Strain Isolated from Honeybee Gut as a Potential Live Oral Vaccine Against Lethal Infection of Salmonella Typhimurium
Authors: ZAFAR HASSAN , RAHMAN SAJJAD UR , ALI SULTAN , JAVED MUHAMMAD TARIQ
Published: June 2019

In this research, Salmonella species were isolated from the animal, insect and human enteric sources in Faisalabad, Punjab, Pakistan. These species were characterized by different microbiological and molecular techniques including polymerase chain reaction (PCR) by amplification of the 16S rRNA gene. Furthermore, sequencing of the amplicons confirmed all ten isolates as Salmonella strains. The antigenic cross-reactivity was found maximum between the HB1 (strain isolated from honeybee) antiserum and its antigen with an antibody titer of 1:128, while the HB1 antiserum showed a cross-reactive titer range of 1:8 to 1:64. On the basis of the highest geometric mean titer (GMT) shown by the antiserum of the HB1 antigen, it was selected as the best candidate for a cross-reactive live Salmonella oral antigen. Moreover, the HB1 antigen was used a live oral antigen (1 × 1010 CFU/ml) in a safety test in rabbits and proved to be avirulent. During the animal trial, three different oral doses of the HB1 live oral antigen were evaluated in four different rabbits’ groups (R1, R2, R3, and R4). The dose number 2 of 0.5 ml (two drops orally and repeated after one week) gave the best GMT measured by indirect hemagglutination (IHA) as compared to the other two doses, while R4 group was kept as control. Results of the challenge protection test also validated the efficacy of the double dose of the HB1 live vaccine, which gave the highest survival percentage. Results of this study lay the foundation for a potential cross-reactive live oral Salmonella vaccine that has proved to be immunogenic in rabbits.
Evaluation of The Pathogenic Potential of Insecticidal Serratia marcescens Strains to Humans
Authors: KONECKA EDYTA , MOKRACKA JOANNA , KRZYMIŃSKA SYLWIA , KAZNOWSKI ADAM
Published: June 2019

We observed the death of insect caterpillars of Spodoptera exigua in the laboratory culture line and identified Serratia marcescens as the bacterial causative agent of the insect death. We confirmed that S. marcescens had insecticidal activity against S. exigua and caused high mortality of larvae. The LC50 values of S. marcescens CFU per 1 cm2 of insect diet surface were similar for all isolates. Our research reports novel strains with high pesticidal activity as candidates for future research on a new bioinsecticide. As bioinsecticides cannot be harmful to non-target organisms, we determined the pathogenic properties of S. marcescens to humans. We proved the ability of S. marcescens to damage mammalian epithelial cells. All strains had cytopathic effects to Vero cells with a cytotoxic index ranging from 51.2% ± 3.8% to 79.2% ± 4.1%. We found that all of the strains excreted catecholate siderophore – enterobactin. All isolates were resistant to sulfamethoxazole, tobramycin, gentamicin, cefepime, and aztreonam. We did not observe the ESBL phenotype and the integrons’ integrase genes. Resistance to sulfamethoxazole was due to the presence of the sul1 or sul2 gene. The use of resistant S. marcescens strains that are pathogenic to humans in plant protection may cause infections difficult to cure and lead to the spread of resistance genes. The results of our study emphasize the necessity of determination of the safety to vertebrates of the bacteria that are proposed to serve as biocontrol agents. The novelty of our study lies in the demonstration of the indispensability of the bacteria verification towards the lack of hazardous properties to humans.
Campylobacter fetus is Internalized by Bovine Endometrial Epithelial Cells
Authors: CAMPOS-MÚZQUIZ LIZETH GUADALUPE , MÉNDEZ-OLVERA ESTELA TERESITA , ARELLANO-REYNOSO BEATRIZ , MARTÍNEZ-GÓMEZ DANIEL
Published: June 2019

Campylobacter fetus is an important venereal pathogen of cattle that causes infertility and abortions. It is transmitted during mating, and it travels from the vagina to the uterus; therefore, an important cell type that interacts with C. fetus are endometrial epithelial cells. Several virulence factors have been identified in the genome of C. fetus, such as adhesins, secretion systems, and antiphagocytic layers, but their expression is unknown. The ability of C. fetus to invade human epithelial cells has been demonstrated, but the ability of this microorganism to infect bovine endometrial epithelial cells has not been demonstrated. Bovine endometrial epithelial cells were isolated and challenged with C. fetus. The presence of C. fetus inside the endometrial epithelial cells was confirmed by the confocal immunofluorescence. C. fetus was not internalized when actin polymerization was disturbed, suggesting cytoskeleton participation in an internalization mechanism. To evaluate the intracellular survival of C. fetus, a gentamicin protection assay was performed. Although C. fetus was able to invade epithelial cells, the results showed that it did not have the capacity to survive in the intracellular environment. This study reports for the first time, the ability of C. fetus to invade bovine endometrial epithelial cells, and actin participation in this phenomenon.
Bacterial Diversity in Soybean Rhizosphere Soil at Seedling and Mature Stages
Authors: WANG LIN , LI ZHIYING , LIU RUIRUI , LI LULU , WANG WEIWEI
Published: June 2019

Changes in the structural diversity of bacterial communities in soybean rhizospheres play important roles in plant growth and crop productivity. However, there are only a few studies on different soybean growth stages. Here, we investigated the changes in the bacterial community of soybean rhizosphere soil at two stages using Illumina high-throughput sequencing. The results showed that the bacterial abundance and diversity in the seeding stage were higher than those in the mature stage and that the diversity changed significantly. Actinobacteria, Acidobacteria, and Proteobacteria were the dominant bacteria in the soybean rhizosphere soil. Additionally, changes in Actinobacteria and Proteobacteria abundances showed opposite trends.
Patterns of Drug-Resistant Bacteria in a General Hospital, China, 2011–2016
Authors: MAO TINGTING , ZHAI HUIJUAN , DUAN GUANGCAI , YANG HAIYAN
Published: June 2019

Drug-resistant bacteria has been a threat to public life and property. We described the trends and changes in antibiotic resistance of important pathogens in a general hospital in Zhengzhou, China from 2011 to 2016, to control antimicrobial-resistant bacteria in hospital and provide support to clinicians and decision-making departments.

Five dominant bacteria were enrolled based on the data from the general hospital during 6 years. The results of antimicrobial susceptibility testing were interpreted according to Clinical and Laboratory Standards Institute (CLSI). From 2011 to 2016, a total of 19,260 strains of bacteria were isolated, of which Klebsiella pneumoniae, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Acinetobacter baumannii accounted for 51.98%. The resistance rate of K. pneumoniae and E. coli to carbapenem was less than 15%, but resistance of K. pneumoniae to carbapenems increased with time and resistance of E. coli to meropenem increased. The rate of extended-spectrum beta-lactamase (ESBL) production among K. pneumoniae and E. coli was decreasing. For most antibiotics, the resistance rate of ESBL-positive isolates was higher than that of ESBL-negative isolates, excluding carbapenems and cefoxitin. For S. aureus, the rate of methicillin-resistant S. aureus (MRSA) was stable. Resistance of S. aureus to mostly antibiotics decreased with time. Besides polymyxin B, P. aeruginosa and A. baumannii showed high resistance to other antibiotics. For A. baumannii, the resistance rate to mostly antibiotics was increasing. The bacteria showed high levels of resistance and multiple drug resistance. Continuous surveillance and optimizing the use of antibiotics are essential.
Gastric Microbiota Alteration in Klebsiella pneumoniae-Caused Liver Abscesses Mice
Authors: CHEN NAN , JIN TONG-TONG , LIU WEN-NING , ZHU DONG-QING , CHEN YING-YING , SHEN YUE-LIANG , LING ZONG-XIN , WANG HONG-JIE , ZHANG LI-PING
Published: June 2019

Gastric microbiota provides a biological barrier against the invasion of foreign pathogens from the oral cavity, playing a vital role in maintaining gastrointestinal health. Klebsiella spp. of oral origin causes various infections not only in gastrointestinal tract but also in other organs, with Klebsiella pneumoniae serotype K1 resulting in a liver abscess (KLA) through oral inoculation in mice. However, the relationship between gastric microbiota and the extra-gastrointestinal KLA infection is not clear. In our study, a 454 pyrosequencing analysis of the bacterial 16S rRNA gene shows that the composition of gastric mucosal microbiota in mice with or without KLA infection varies greatly after oral inoculation with K. pneumoniae serotype K1 isolate. Interestingly, only several bacteria taxa show a significant change in gastric mucosal microbiota of KLA mice, including the decreased abundance of Bacteroides, Alisptipes and increased abundance of Streptococcus. It is worth noting that the abundance of Klebsiella exhibits an obvious increase in KLA mice, which might be closely related to KLA infection. At the same time, the endogenous antibiotics, defensins, involved in the regulation of the bacterial microbiota also show an increase in stomach and intestine. All these findings indicate that liver abscess caused by K. pneumoniae oral inoculation has a close relationship with gastric microbiota, which might provide important information for future clinical treatment.
The State of Research on Antimicrobial Activity of Cold Plasma
Authors: NIEDŹWIEDŹ IWONA , WAŚKO ADAM , PAWŁAT JOANNA , POLAK-BERECKA MAGDALENA
Published: June 2019

Microbiological contamination is a big challenge to the food industry, medicine, agriculture, and environmental protection. For this reason, scientists are constantly looking for alternative methods of decontamination, which ensure the effective elimination of unwanted biological agents. Cold plasma is a new technology, which due to its unique physical and chemical properties becomes a point of interest to a growing group of researchers. The previously conducted experiments confirm its effective action, e.g. in the disinfection of skin wounds, air, and sewage treatment, as well as in food preservation and decontamination. The reactive compounds present in the plasma: high-energy electrons, ionized atoms and molecules, and UV photons are the key factors that cause an effective reduction in the number of microorganisms. The mechanism and effectiveness of the cold plasma are complex and depend on the process parameters, environmental factors and the type and properties of the microorganisms that are to be killed. This review describes the current state of knowledge regarding the effectiveness of the cold plasma and characterizes its interaction with various groups of microorganisms based on the available literature data.