bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of Cascara Business Competition Using Porter’s Five Forces Model at PT Agritama Sinergi Inovasi
Authors: Gika Eline Nuha Nurrohmah , Purwaamijaya Btari Mariska , Maesaroh Syti Sarah
Published: February 2025

The cascara market in Indonesia has great potential due to the increasing interest in health-oriented beverages. However, PT Agritama Sinergi Inovasi (AGAVI) faces competitive challenges in the form of high supplier bargaining power, lack of awareness of the domestic market, and threats from substitute products such as tisane and herbal tea. This study aims to analyze the level of competition in the cascara business of PT Agritama Sinergi Inovasi (AGAVI) using Porter's Five Forces model. The research method used is a qualitative approach through interviews, observations, and documentation to collect data. Data analysis was carried out descriptively with source triangulation to ensure the validity of the findings. The results of the analysis show that the bargaining power of suppliers is at a high level, while the bargaining power of buyers and the threat of newcomers are at a medium level. The threat of substitute products is at a low level, while the level of competition between competitors is at a medium level, providing innovation opportunities for AGAVI. This research contributes to enriching the understanding of business competition in the health-based beverage market, especially in the sustainability-based beverage industry. These findings provide insights for AGAVI to improve competitiveness by expanding markets, especially for customer loyalty in the B2C segment, market education, and strengthening partnerships with local coffee farmers, while creating additional income opportunities for coffee farmers and supporting industry sustainability.
Plan de negocios para la creación de una barbería móvil innovadora: Barber Truck, Lima Metropolitana
Authors:   , Aguirre Requena Jorge Augusto , Ahuanari Ochovano Joel Fernando , Diestra Ortiz Rodrigo Armando , Jara Tumbalobos Anabel Patricia , Zavala Agapito de Zavala Lourdes Karina
Published: February 2025

"Barbertruck se establece con la visión de convertirse en la marca líder en servicios de barbería móvil en Perú, ofreciendo una experiencia de cuidado personal para hombres que combina innovación, confort y alta calidad. Su misión es proporcionar servicios de barbería personalizados y de alta calidad directamente a los clientes, con el objetivo de mejorar su confianza e imagen personal. La propuesta de valor de Barbertruck se distingue al ofrecer una experiencia única de barbería móvil que elimina las molestias asociadas a las barberías tradicionales, tales como las largas esperas y desplazamientos. Este enfoque se centra en la conveniencia, llevando el servicio directamente al cliente, ya sea en su hogar, oficina o durante eventos, todo en un ambiente exclusivo y personalizado que realza la experiencia del usuario.
El análisis de mercado revela que el público objetivo son hombres entre 18 y 45 años en Lima, que están interesados en el cuidado personal y las tendencias de moda. Se estima un mercado total direccionable (TAM) anual de S/127,800,000, con un enfoque particular en los segmentos socioeconómicos A y B, lo que indica un alto potencial de crecimiento. En cuanto a las estrategias de marketing, el plan contempla el desarrollo de una sólida presencia digital que incluirá un programa de fidelización para mantener a los clientes comprometidos, el establecimiento de alianzas estratégicas con marcas afines, y el lanzamiento de una línea de productos de cuidado personal que complemente los servicios ofrecidos.
Por lo tanto, con estas estrategias, se espera incrementar la participación de mercado en un 25% y alcanzar un reconocimiento de marca del 70% en el primer año de operaciones..."
Determinación de cristaluria de cistina en caninos asintomáticos en dos distritos de Lima metropolitana - Perú
Authors:   , Albines Santolalla Liz Dianeth Noemi
Published: February 2025

La presencia de cristales de cistina se origina por una alteración genética a nivel renal, generando una mala reabsorción de esta en el túbulo renal y como consecuencia se da una sobreacumulación de este aminoácido, formando los cristales. El objetivo del presente estudio transversal fue evaluar la presencia de cristales de cistina en caninos asintomáticos en dos distritos de Lima Metropolitana. Se colectaron 161 muestras de orina de canes asintomáticos de manera aleatoria. Las muestras fueron procesadas en el laboratorio clínico de la Clínica Veterinaria Municipal de San Miguel mediante microscopía directa para la detección de los cristales de cistina. También, se consideraron otras covariables como el sexo, edad, raza, tipo de alimentación y capacidad reproductiva. Dentro de los resultados, el total de participantes fue de 161 caninos que, procedieron de los distritos del Rímac (60) y San Miguel (101). Con relación a la presencia de cristales de cistina en perros no se encontró a ningún positivo, pero si se evidenció a cristales de bilirubina (0.6%), oxalato de calcio (1.2%) y fosfato triple o estruvita (19.3%).
Evaluación del desempeño de la gestión ambiental en seis municipalidades de Lima en el año 2023, en base al análisis comparativo de la norma ISO 14001:2015 y de la guía para el funcionamiento del sistema local de gestión ambiental
Authors:   , Diez Torricelli Jose Antonio
Published: February 2025

"El Sistema de Gestión Ambiental debe integrarse plenamente en la función municipal, considerándose desde la planificación de la Programación Multianual Presupuestaria y en la Formulación Presupuestaria anual (Ministerio de Economía y Finanzas, 2022), para su posterior ejecución a través de sus respectivos planes estratégicos y operativos institucionales. Además, se requiere un seguimiento y control constante para garantizar una implementación efectiva de la gestión ambiental a nivel municipal. Esto implica realizar evaluaciones periódicas del desempeño mediante auditorías, con el objetivo de fomentar la mejora continua.
Mediante la presente investigación, se realizó un análisis comparativo entre la Guía para el funcionamiento del Sistema Local de Gestión Ambiental aprobada por el Ministerio del Ambiente, con Resolución Ministerial Nº 131-2021-MINAM, y la norma ISO 14001:2015 – SGA, estándar internacional de carácter voluntario, para el análisis del funcionamiento del Sistema Local de Gestión Ambiental de las siguientes seis (6) municipalidades distritales de Lima Metropolitana: Cercado de Lima, San Borja, Carabayllo, La Victoria, Santa María del Mar, y Magdalena del Mar.
Inicialmente, para el análisis se utilizó la estructura de la ISO 14001:2015 – SGA, que permitió ordenar los criterios para la posterior evaluación, separándolo en seis (6) apartados. Dicho análisis reveló un desempeño general similar, entre los seis municipios. Sin embargo, al disgregar la evaluación por apartado, se identificaron las problemáticas internas y externas que presentaron cada municipalidad, ayudando a entender la raíz de la problemática ambiental en cada una de ellas. Asimismo, se evidenció que el inadecuado análisis del contexto de sus respectivos distritos y la mala planificación ambiental, reflejaron la falta de un adecuado liderazgo por parte de la alta dirección (alcalde y consejo municipal) en la gestión ambiental..."
Analítica aplicada al Plan Nacional de Desarrollo 2022-2026: “Colombia, potencia mundial de la vida”
Authors: Arrieta-Díaz Enrique , Maldonado-Agudelo Rafael , Vargas-Prieto Amanda
Published: February 2025

Teniendo en cuenta la importancia de los planes de desarrollo para un país, y las dificultades de entender las propuestas de manera objetiva y neutra. Este artículo propone el análisis del PND 2022-2026: “Colombia, potencia mundial de la vida”, a través de la minería de texto. Los principales resultados fueron: la identificación de los 23 temas dentro del PND y los términos que incluyen. El término más importante es Colombia, seguido de paz, discapacidad, género y alimentos. Los dos primeros representan los temas con el mismo nombre. Siendo coherente con el eje transversal del PND, la consecución de la paz total en Colombia. Los otros tres términos están dentro de los temas de mujeres e inclusión, alimentación y mujeres, nuevamente. El análisis permitió la identificación de los bigramas y trigramas con mayor frecuencia en el PND. Siendo el más frecuente gobierno-nacional, mientras que el trigrama más frecuente es: plan-nacional-desarrollo. Este análisis evidencia que en el PND, la paz, las minorías, la alimentación, la educación, el transporte y los derechos humanos son protagonistas. La inversión es de los temas más relevantes en el PND. Los dos aspectos centrales del tema educación y salud se encuentran en una variedad de aspectos que hacen que su especificidad sea baja y su relevancia sea media. Sin embargo, es un tema transversal en el PND. Al revisar la correlación de los temas se observa que los temas fundamentales del PND son: infraestructura, paz, agua, desarrollo rural y cultura y recreación.
Artificial Intelligence for Root Canal Segmentation on Radiographic Images: A Scoping Review
Authors: Ghiasi Maryam , Zaboli Ava , Mahdian Mina , Mallya Sanjay M.
Published: February 2025

Objectives: The number, size, patency, and location of pulp canals are critical in endodontic treatment planning. This information is currently obtained through visual radiographic assessment, which is time-consuming and labor-intensive. Artificial intelligence (AI) could automate this task via accurate segmentation of root canals providing efficiency and consistency. This scoping review maps existing literature on the use of AI to automate root canal segmentation on radiographic images.
Materials and Methods: We searched MEDLINE (Ovid), Embase, Scopus, and Web of Science for relevant studies up to January 8, 2025. Studies that used AI for root canal segmentation were included. Study selection was not limited by design, language, or date. Commentaries, retracted articles, and inaccessible full-text articles were excluded. Titles and abstracts were screened based on eligibility criteria, and the full-text of potentially relevant studies was assessed. Screening and data extraction were conducted in duplicate by independent reviewers, with disagreements resolved via consensus or a third-reviewer if necessary.
Results: Out of 836 articles identified, 35 studies met the eligibility criteria and were retained for synthesis. Data extraction focused on the country of origin, study design, imaging modalities, obturation status, type of teeth analyzed, AI models used, and results. Modalities included were mostly cone beam computed tomography (CBCT, 51%), followed by panoramic (17%) and periapical (14%). AI-based models, particularly those employing CNNs, reported accuracies ranging from 0.73 to 0.99 and sensitivities from 0.72 to 1. These models were effective across all imaging modalities with most studies reporting improved diagnostic precision and reduced time compared with manual methods.
Conclusions: AI-based root canal segmentation has clinical value by increasing accuracy in identifying root canal anatomy prior to treatment. This will preserve clinicians' time and reduce the risk of treatment failure. This review highlights current status of this technological application and identifies areas to refine these technologies for broad clinical application to enhance patient outcomes in endodontic care.
Clinical Relevance: The application of AI in root canal segmentation offers significant clinical benefits by improving the accuracy and efficiency of identifying root canal anatomy. This can lead to better treatment planning, reduced procedure times, and lower risk of endodontic failure. As AI technology continues to evolve, its integration into endodontic practice has the potential to enhance patient outcomes and streamline clinical workflows.
Projecting the impacts of future climate change on precipitation in the Kashafrud catchment in Iran
Authors: Imanipour Hossain , Karami Mokhtar , Kashki Abdolreza , Esmailnejad Morteza
Published: February 2025

Climate change is known as one of the most critical challenges facing humanity. These changes seriously threaten the Kashafrud River, a significant water resource in northeastern Iran. This study aims to project the impact of climate change on precipitation in the Kashfrud catchment in Iran. The output data of global climate models, including ACCESS-ESM1-5, MRI-ESM2-0, and MIROC6 from the sixth-generation models (CMIP6), have been used to project future climate changes. Based on the accuracy of statistical criteria, the linear scaling (LS) method was employed to do the bias correction of precipitation data. Then, using the CMhyd model, the precipitation data were simulated for the two future periods (2025-54) and (2055-84) under the SSP1_2.6 and SSP5_8.5 scenarios. The average KGE and RMSE coefficients for the precipitation of the selected MIROC6 model were obtained as 0.91 and 21.09, respectively. Average annual rainfall under the scenarios of SSP1_2.6 and SSP5_8.5 in the near future period decreased by 2.92% and increased by 3.44%, respectively. Average annual rainfall was projected as follows: under the SSP1_2.6 and SSP5_8.5 scenarios in the near future period, it decreased by 2.96% and increased by%3.44, and under the SSP1_2.6 و SSP5_8.5 scenarios in the middle future period, it increased by 2.96% and 8.79%, respectively compared to the observation period (1991–2020). In terms of seasonal comparison, in most of the scenarios of the future periods, in the spring and autumn seasons, precipitation will decrease between 1.51% and 8.18%. Precipitation in the future seasons in summer and winter was projected with a slight increase. The results showed that climate change will have a significant impact on the precipitation of the study area. This can have severe consequences for different sectors, including agriculture, industry, and the environment. The research results can be employed as a management tool in the direction of water resources management.
Acute Myocardial Infarction Revealing a Patent Foramen Ovale in a 37-Year-Old with a History of Unexplored Transient Ischemic Attack: A Case Report
Authors: Obeidat Saleh muhammed , Elkerrami Khlid , Lemaitre Ann-Iris , Himeur Yazid
Published: February 2025

Introduction
A patent foramen ovale (PFO) is a common congenital anomaly that can lead to severe complications through paradoxical embolism, particularly in young patients with no classical cardiovascular risk factors. Myocardial infarction with non-obstructive coronary arteries (MINOCA) represents a minority of acute coronary syndrome cases but is clinically significant due to its heterogeneous and often unclear etiologies. Among these, PFO-related paradoxical embolism is a rare but critical cause requiring prompt recognition and management.
Case Presentation
We report the case of a 37-year-old man with no cardiovascular risk factors, presenting with acute chest pain and dyspnea. His medical history revealed a transient ischemic attack (TIA) at age 25, which had remained unexplored. At presentation, the patient exhibited signs of an acute myocardial infarction (ST-elevation in inferior leads and elevated troponin). Coronary angiography revealed non-obstructive coronary lesions, confirming MINOCA. Echocardiographic evaluation identified a PFO with a right-to-left shunt, while cardiac MRI findings were consistent with ischemia in the infero-basal myocardium. The diagnosis of MINOCA secondary to paradoxical embolism through the PFO was established. The patient was treated with anticoagulation (Rivaroxaban) and underwent successful percutaneous PFO closure.
Discussion
MINOCA is a multifactorial clinical entity requiring advanced diagnostic tools to uncover its etiology. In this case, the detection of a PFO linked the myocardial infarction to the patient’s prior unexplained TIA, supporting a paradoxical embolic mechanism. Cardiac magnetic resonance imaging played a pivotal role in confirming the ischemic nature of the event, while intracoronary OCT ruled out significant plaque instability. Percutaneous closure of the PFO was performed to prevent recurrent embolic events. Although commonly indicated for cryptogenic strokes, PFO closure in MINOCA patients remains less established and highlights the need for further research to guide management.
Conclusion
The discovery of a PFO in the context of myocardial infarction in a young patient without pre-existing coronary disease highlights the need for thorough evaluation of underlying causes. Management includes pharmacological treatment and close monitoring, with PFO closure as a potential option to prevent future thromboembolic events.
Understanding the role of traditional healers in the Malawian healthcare system: a qualitative study
Authors: Master Riya , Mguntha Andrew , Baltzell Kimberly , Bandawe Gama , Hooft Anneka
Published: February 2025

Introduction
Malawi is a pluralistic health system, where people seek care from both formal (e.g. biomedical) and informal (e.g. traditional medicine) sources. An estimated 80% of the population utilizes traditional healers (TH) for care, particularly in rural areas. Given their strong community presence, TH may be able to bridge gaps in the healthcare system, however, data on barriers and facilitators to this relationship are limited. Understanding TH perspectives on disease processes and their role in the community is critical to integrating TH into the biomedical system.
Methods
We conducted a qualitative study using semi-structured interviews of TH in Thyolo District, Malawi in May 2024. Participants were identified and recruited using purposive sampling. Interviews were conducted in Chichewa, translated into English, and coded for themes.
Results
We interviewed a total of 25 TH: 17 male and 8 female, age 25 to 84 years. Time in practice ranged from 8 months to 60 years. Major themes identified included: 1. Relationship-building for diagnosis and treatment; 2. Trust and willingness to collaborate with biomedicine; 3. Compensation for gaps in the biomedical system; 4. Recognition of causes and risk factors for infection; and 5. Leadership role in the community.
Conclusions
In Malawi, TH demonstrate a strong desire for recognition, training, and integration into the biomedical system. Understanding of disease processes outside of traditional vs. biomedical illnesses is variable, but most TH trust biomedicine and feel comfortable referring clients. Given their respected role in society, TH may provide a useful adjunct to biomedical care in rural Malawi.
Dynamics based screening of Therapeutic compounds against Helicobacter pylori targeting TNF-α inducing protein
Authors: Raj Divya S , Priyadarshini K. Chidhambara , Yadav Shalini , Singh Sukriti , Dwivedi Manish
Published: February 2025

In about half of the world's population, Helicobacter pylori (H. pylori) is the cause of stomach ulcers. Due to the extensive use of different drugs to treat H. pylori infections, multidrug resistance has developed, making treatment more difficult. Finding a viable therapeutic target becomes increasingly important as antibiotic resistance keeps increasing. A distinct protein of H. pylori called Tumour Necrosis Factor-alpha Inducing Protein (Tip-α) is important in the development of gastric cancer, especially in patients with chronic ulcers. Because of its vital role, Tip-α may be a good target for medication. Using molecular docking experiments, two different binding sites on Tip-α were found, and possible inhibitors were assessed. ZINC11981988 and ZINC04243820, two ZINC database hits among the screened compounds, showed a significant binding affinity to Tip-α, with glide scores of -9.116 kcal/mol and -10.455 kcal/mol, respectively. A MM-GBSA analysis was conducted to have a better understanding of their binding mechanisms. The findings showed that the selectivity of Tip-α inhibitors was more influenced by electrostatic energy contributions than by van der Waals interactions. The stability of these ligands in their respective binding sites was evaluated using molecular dynamics (MD) simulations upto 100 ns. In contrast to ZINC11981988, ZINC04243820 showed a more stable binding association with Tip-α, according to the MD analysis. According to this, ZINC04243820 exhibits excellent binding stability and is therefore a promising candidate for additional research. Considering these results, ZINC04243820 could be proposed as potential lead to construct Tip-α inhibitors against H. pylori which shows favourable interaction properties and persistent binding. Further, in vivo and in vitro investigations are required to examine and validate its therapeutic potential.
Wired for Risk: ADHD’s Influence on Financial Behavior in Stock Trading
Authors: Witry Max , Schulze Marcel , Braun Niklas , Rohner Henrik , Weller Johannes , Philipsen Alexandra , Kölle Markus
Published: February 2025

Importance
Attention Deficit Hyperactivity Disorder (ADHD) is highly prevalent and presents significant health, social and economic risks. However, its impact on long-term financial strategies and personal financial management remains poorly understood. Gaining deeper insight is essential due to its wide-ranging societal implications.
Objective
To investigate the impact of ADHD on financial behavior and individual portfolio performance in a trading community.
Methods
A cross-sectional survey was conducted in 1520 individuals interested in stocks and finance, recruited through financial and health-focused online platforms. After excluding incomplete or ineligible responses, 945 participants were included in the analysis. ADHD traits and financial risk tolerance (FRT) were assessed using standardized, validated self-report questionnaires. Data on trading frequency, portfolio performance and other variables were based on participant’s individual reports.
Results
The study examined 945 participants, with a median age of 34 years and 74.5% male. Among them, 54 individuals (5.7%) met DSM-5 criteria for an ADHD diagnosis and were classified as ADHD positive. This group demonstrated greater FRT (p=0.025) and speculative risk-taking (p=0.015). ADHD traits showed a positive correlation with FRT (r = 0.079, p = 0.015) and a negative correlation with portfolio returns (r = -0.075, p = 0.02). Regression analyses identified trading frequency (B=0.769, p=0.046), speculative risk-taking (B=0.675, p=0.034) and higher portfolio expectations (B=1.237, p=0.041) as positive predictors of ADHD symptom scores. In contrast, higher portfolio returns (B=-1.067, p=0.019) and the investment risk score (B=-0.590, p=0.034) were negative predictors of ADHD traits.
Conclusions
The study revealed a higher than expected ADHD prevalence among participants, along with above-average FRT scores. Increased ADHD traits were associated with higher trading frequency and speculative risk-taking, while investment risk and portfolio returns were negatively impacted. These findings suggest that individuals with a high burden of ADHD traits may face significant challenges in financial decision-making, particularly in high risk trading settings such as speculative stock trading, where the potential for losses is heightened.
Asymptotic symmetries in the $TsT/T\bar{T}$ correspondence
Authors: Du Zhengyuan , Lai Wen-Xin , Liu Kangning , Song Wei
Published: February 2025

Starting from holography for IIB string theory on AdS_3× \mathcal N3×𝒩 with NS-NS flux, the TsT/T\bar TTT‾ correspondence is a conjecture that a TsT transformation on the string theory side is holographically dual to the single-trace version of the T\bar TTT‾ deformation on the field theory side. More precisely, the long string sector of string theory on the TsT-transformed background corresponds to the symmetric product theory whose seed theory is the T\bar TTT‾-deformed CFT_22. In this paper, we study the asymptotic symmetry of the string theory in the bulk. We find a state-dependent, non-local field redefinition under which the worldsheet equations of motion, stress tensor, as well as the symplectic form of string theory after the TsT transformation are mapped to those before the TsT transformation. The asymptotic symmetry in the auxiliary AdS basis is generated by two commuting Virasoro generators, while in the TsT transformed basis is non-linear and non-local. Our result from string theory analysis is compatible with that of the T\bar TTT‾ deformed CFT_22.
A HOLISTIC APPROACH TO HPLC TECHNIQUEFOR ADDRESSING PROCESS IMPURITIES: REVIEW ONMETHOD DEVELOPMENT, OPTIMIZATION, AND VALIDATION
Authors:   Department of Chemistry, Anurag University, Hyderabad, India., Chandrashekhar Reddy P. , Sampath Kumar Reddy G. ,   Analytical Research and Development, Aurore Life Sciences Private Limited, Hyderabad, India., Jainendra Kumar B. ,   Department of Pharmacy, Anurag University, Hyderabad, India.
Published: February 2025

High-Performance Liquid Chromatography (HPLC) has become an indispensable analytical tool in pharmaceutical, environmental, and food sciences due to its precision, sensitivity, and versatility. A holistic approach to HPLC method development, optimization, and validation ensures reliable and reproducible results while meeting regulatory requirements. This review outlines the critical steps in HPLC method development, emphasizing the importance of understanding analyte properties, selecting appropriate chromatographic conditions, and fine-tuning parameters for optimal performance. Key aspects of method optimization, such as mobile phase composition, column selection, flow rate, and pH, are discussed to enhance resolution and reduce analysis time. Additionally, the article delves into the rigorous validation process, which includes assessing accuracy, precision, specificity, linearity, and robustness in compliance with International Council for Harmonisation (ICH) guidelines. By integrating systematic method development, experimental optimization, and thorough validation, this holistic framework ensures efficient and high-quality analytical methods, driving advancements in research and quality assurance across various industries.
Impact of knowledge management, knowledge sharing, and mental accounting on farmer performance in Sasi culture in Maluku Islands, Indonesia
Authors: Handayani Amaliah Tri
Published: February 2025

The welfare of farmers and agricultural productivity are significantly influenced by challenges in business and financial management. This study investigates how knowledge management, knowledge sharing, and mental accounting impact farmer performance within the unique context of Sasi culture in Maluku Islands, Indonesia. Knowledge management provides farmers with the tools to acquire, utilize, and apply agricultural insights, while mental accounting shapes their financial decision-making and resource allocation. Using a mixed-method approach that combines WarpPLS and ethnomethodology, data were gathered through questionnaires distributed to 65 respondents and in-depth interviews with selected participants. The analysis revealed that knowledge management significantly impacts farmer performance with a path coefficient of 0.717 (p < 0.001), while mental accounting also has a positive effect with a coefficient of 0.164 (p = 0.050). However, knowledge sharing did not significantly affect performance (coefficient = 0.372, p = 0.382). The results suggest that Sasi culture, deeply rooted in local wisdom, helps integrate knowledge management and mental accounting to improve farmer welfare and agricultural income. Despite the ineffectiveness of formal knowledge sharing, the cultural practice of Sasi inherently promotes the sharing of knowledge within the community, enhancing the overall management of agricultural practices. This study emphasizes the role of local wisdom in creating sustainable agricultural practices and highlights the potential of Sasi culture to synergize modern knowledge management with traditional financial behaviors.
Effect of dietary Azolla supplementation on growth performance and histomorphometric features of the small intestine in broilers
Authors: KESER ONUR , YİGİT FUNDA , BİLGİN AYSE SEBNEM , ABAS ISMAİL , BİLAL TANAY , KUTAY HALİL CAN
Published: February 2025

This study was carried out to investigate the effects of Azolla pinnata supplementation on growth performance and intestinal histomorphometric parameters in broilers. A total of 480 day-old male broiler chicks (BW = 38.85 ± 0.16 g) were assigned to four groups for eight replicates (15 chicks for each). Chicks in the control group were fed basal diet, and experimental groups were fed diets containing Azolla (AZL) at a rate of 3% (AZL3), 4% (AZL4) and 5% (AZL5), respectively during 21 days. At the end of the experiment (day 21), the AZL3 group had significantly higher body weight than the control and other experimental groups. A significant decrease in body weight values was found when the amount of Azolla in the diets increased above 3%. No significant difference between the control and AZL3 group for average daily gain between days 0-21, but AZL4 and AZL5 groups had a significantly lower average daily gain compared to these two groups. Compared to the other experimental groups and the control group, the feed conversion rate significantly improved in the AZL3 group. According to histomorphometric data of duodenum, jejunum and ileum tissue samples obtained from the groups at the end of the experiment, it was determined that AZL3 had significantly higher villus height, villus width, villus surface area, villus height to crypt depth ratio, thickness of Tunica muscularis and Tunica mucosa, and lower crypt depth than the control and other experimental groups. As a result of this sudy, Azolla supplementation exceeding 3% to broiler diets had no significant advantage on both performance and intestinal histomorphometric parameters.
Emociones en campaña: Impacto de la influencer Mariana Rodríguez en las elecciones de Nuevo León
Authors: López-Aguirre José-Luis , López-Arce Selena-Sarai
Published: February 2025

This research analyzed the emotional contagion of posts by the Mexican influencer Mariana Rodríguez on Instagram during the 2021 electoral campaign for the governorship of Nuevo León, in which her husband, Samuel García, was elected. Using a mixed-methods approach that combined quantitative and qualitative analysis, the emotions expressed in both Rodríguez’s posts and user comments were examined. The findings show that the predominant emotion was happiness, a high-arousal positive emotion, which prompted followers to actively engage through “likes,” comments, and shares. This emotional contagion not only enhanced the candidate Samuel García’s image but also positioned the couple as significant figures in the campaign’s political narrative. Additionally, emojis and specific expressions like “fosfo fosfo” emerged as symbols of party support, highlighting the importance of linguistic and visual resources in building political identity on social media. This study underscores the role of influencers in digital political communication and calls for updating emotional analysis tools to reflect the evolution of digital language on social platforms.
Multiresidue Pesticide Analysis in Cereal Grains Using Nanosized γ‑Aluminum Oxide as Effective Purification Material
Authors: Guan Wenbi , Lian Hengrui , Cai Yunjin , Yao Su , Wang Hongwu
Published: February 2025

This study demonstrated the application of nanosized γ-aluminum oxide as dispersive
solid-phase extraction (d-SPE) sorbent to pesticides multi-residue analysis in cereal grains by gas
chromatography combined with orbitrap mass spectrometry (GC-Orbitrap-MS). The influence of
structural phase, particle size, and usage amount of nanosized aluminum oxide were investigated
on d-SPE cleanup performance. The ability of nanosized γ-aluminum oxide to clean up interfering
substances from ethyl acetate extracts of cereal grains was also evaluated. Compared with common
d-SPE sorbents (i.e., primary secondary amine (PSA), basic alumina, neutral alumina, acidic
alumina, octadecylsilane (C18), florisil, graphitized carbon black (GCB), and nanosized ferroferric
oxide (Fe3O4)), 10 nm γ-aluminum oxide was cost-effective and exhibited much better cleanup
performance with 99.72% removal of eluting matrix components for wheat kernel. Meanwhile,
a multiresidue method was validated on 24 representative pesticide residues in three cereal
grains (wheat kernel, rice, and corn). Acceptable average recoveries of 71.1-117.0% and relative
standard deviations (RSDs) < 12.7% were obtained for all target pesticides. The method met the
5-10 μg L−1 limit of detection and 10-20 μg kg−1 limit of quantification. The results indicated that
10 nm γ-aluminum oxide represented an affordable and effective d-SPE adsorbent for pesticides
multiresidue analysis in cereal grains.
Spatiotemporal variations of nitrogen-nitrate in groundwater and health risk in the parts of Mu Us sandy land, NW China
Authors: Duan Rui , Gu Xiaofan , Chang Liang , Cui Xudong , Li Xiaodeng , You Xiangzhi , Zhang Qunhui
Published: February 2025

Nitrate pollution is a major threat caused by intensive agricultural activities in semi-arid regions. This study focuses on the Da Niudi Gas Field in the Mu Us Sandy Land. Groundwater quality dynamics were assessed through analysis of 100 sampling points from 2012, 2015, and 2022. The maximum concentrations recorded were 476 mg/L for NO3−, 0.26 mg/L for NO2−, and 1.61 mg/L for NH4+. Principal component analysis (PCA) and correlation analysis reveal that groundwater chemistry is influenced by mineral dissolution, agricultural activities, and wastewater discharge. The Entropy Water Quality Index (EWQI) was used to evaluate groundwater quality, indicating an overall decline with nitrate pollution showing spatial variability. A health risk assessment model was developed to evaluate health risks for local residents. Results show significant health risks from elevated concentrations of NO3−, NO2−, and NO4+. In 2012, health risks were within acceptable limits, but by 2015, 50% of children and 12.5% of adults exceeded these limits. In 2022, these percentages decreased to 5.36% for children and 1.79% for adults. These findings emphasize the urgent need for measures to reduce nitrate pollution in the area.
Os gêneros discursivos emergentes da internet no ensino de língua portuguesa
Authors:   , Trajano Maria Francileide de Oliveira
Published: February 2025

Nesta dissertação, abordamos a inclusão dos gêneros discursivos emergentes da internet no livro didático para o ensino e à aprendizagem da Língua Portuguesa, cujo suporte apresenta-se como um dos principais recursos didáticos de atividades do professor de Língua Portuguesa do Ensino Médio da rede pública e como material de aprendizagem mais distribuído aos alunos, nacionalmente. Na pesquisa, indagamos: Como os gêneros discursivos emergentes da internet podem ser utilizados para o ensino de Língua Portuguesa? A partir dessa questão, objetivamos analisar como os gêneros discursivos emergentes da internet são trabalhados no livro didático “Português: contexto, interlocução e sentido”, de Abaurre; Abaurre; Pontara (2013). Com abordagem qualitativa, a presente pesquisa fundamenta-se nas teorias de autores que possibilitaram evidenciar a importância das Tecnologias da Informação e Comunicação para o desenvolvimento da sociedade e a formação do cidadão para sua inserção; o constante uso dos gêneros discursivos emergentes da internet pelos alunos da primeira série do Ensino Médio e a apresentação de alguns deles; a possibilidade de utilização desses gêneros para o desenvolvimento do processo de ensino-aprendizagem na disciplina de Língua Portuguesa, e; a necessidade de capacitação dos professores nesses meios tecnológicos como forma enriquecedora de suas práticas e experiências contextualizadas. No que toca à metodologia, caracteriza-se sob a forma de análise documental do livro didático da primeira série do Ensino Médio, com a finalidade de saber se as propostas dos documentos oficiais quanto à importância das tecnologias para o ensino de Língua Portuguesa são atendidas, e como é feita a contextualização sobre o uso de novos gêneros discursivos em sala de aula. Os dados obtidos, apontam para uma superficial e limitada presença desses gêneros discursivos emergentes da internet na coleção examinada, com atividades didáticas propostas apenas para o gênero e-mail, com centralização em gêneros discursivos oriundos das esferas literária, jornalística e publicitária, e a predominância e valorização do suporte impresso. No geral, podemos concluir que o livro não apresentou nenhuma proposta inovadora que acompanhe as mudanças sociais, culturais e tecnológicas da sociedade atual e da emergência dos múltiplos conhecimentos possíveis de serem construídos na escola através dos gêneros discursivos emergentes da internet
Jogos digitais no ensino de história: uma análise do jogo tríade - igualdade, liberdade e fraternidade
Authors:   , Mota Marcos César Alves da
Published: February 2025

Os jogos digitais, em especial os educativos, são assinalados como uma ferramenta
viável para a utilização no ambiente escolar, visto que insere os discentes em um momento
lúdico de aprendizagem, possibilitando o desenvolvimento de diversas habilidades. Todavia,
há vezes que não é possível para o docente a obtenção de jogos que adequem-se à finalidade
escolar, tanto no que diz respeito ao público quanto aos recursos disponíveis, inviabilizando o
uso desses recursos no contexto escolar. Baseado nesse contexto, objetivamos analisar quais as
contribuições do jogo Tríade - Igualdade, Liberdade e Fraternidade para o ensino de História.
A abordagem da pesquisa é qualitativa, de naturezas exploratória e explicativa. A investigação
ocorreu de forma participativa, tanto pelo pesquisador como pelos partícipes da pesquisa, o que
proporcionou uma compreensão mais ampla não apenas quanto ao uso dos jogos digitais no
ensino, mas também as limitações e os percalços para o uso. A pesquisa, iniciou com a
realização de uma análise acerca do que é considerado jogo e quais as contribuições dessa
ferramenta para o processo de ensino. Para isso, nos amparamos em Arruda (2011), Petry
(2016) e Alves (2015) cujas leituras percebemos o jogo Tríade - Igualdade, Liberdade e
Fraternidade dentro dos padrões relatados pelos autores. Posterior à fase de análise e a escolha
do jogo, iniciamos a etapa de revisão de documentos disponibilizados pelos seus idealizadores
para entender o desenrolar do fato histórico usado como cenário para a trama do jogo e, na
sequência, realizar sua aplicação e os efeitos do uso dessa ferramenta no que toca à
aprendizagem. Os resultados, cooperam para as futuras pesquisas, tanto no que diz respeito ao
fator teórico quanto prático, na definição de jogos digitais educativos e suas contribuições para
o processo de ensino-aprendizagem. Consideramos que o jogo utilizado nesta pesquisa é uma
possibilidade viável a ser empregada no ambiente escolar, visto que foi desenvolvido com fim
educativo e cujo cenário é composto por evento histórico, no qual o aluno poderá imergir ao
jogá-lo. Esta pesquisa visou proporcionar a professores e alunos a possibilidade de aprender
brincando/jogando, a colaborar de forma eficaz nos resultados dos alunos/jogadores, resultando
em uma aprendizagem significativa, a reforçar os conceitos já abordados nas aulas expositivas,
assim como estimular o aluno/jogador a buscar novos conhecimentos acerca do tema abordado
no jogo, conhecimento este que poderão ser aproveitados por aqueles em situações fora do jogo
Educação estatística na perspectiva CTS: uma proposta de sequência didática para o ensino de estatística no ensino médio
Authors:   , Nascimento Augusto Sávio Guimarães do
Published: February 2025

Este trabalho tem como objetivo geral apresentar uma proposta de sequência didática numa abordagem Ciência-Tecnologia-Sociedade (CTS) para o ensino de estatística no Ensino Médio. Compreende-se que o produto de ensino adotado é uma alternativa a qual contribui na formação de atitudes crítico-reflexivas em relação à ciência e à tecnologia, permitindo aos alunos elucidar o comprometimento do conhecimento estatístico para com o contexto social. As principais âncoras teóricas relacionas à Educação Estatística, que dão sustentação a esta pesquisa, baseiam-se em Campos, Wodewotzki e Jacobini (2011), Cazorla, Kataoka e Silva (2010), Delmas (2002), Gal (2002), Runsey (2002), Costa e Capovilla (1997), Walton (1990), Nisbett (1993), Garfield (2002), Delmas (2002), entre outros. Os encaminhamentos metodológicos fundamentam-se em uma abordagem de cunho quantitativa-qualitativa de acordo com o paradigma emergente, cujas análises levaram a estruturar a sequência didática para ensinar Estatística com abordagem CTS no Ensino Médio. Os fundamentos metodológicos da natureza da pesquisa estão apoiados nas argumentações de Moreira (1990), Minayo (1993), Filho e Gamboa (1997), Grecca (2002), Günther, 2006, Tonzoni-Reis (2009), Gerhardt e Silveira (2009) e Silveira e Córdova (2009). Assim, foi desenvolvido, neste trabalho, na modalidade de estado da arte, a partir de teses e dissertações, um estudo sobre as produções acadêmicas no campo da Educação Estatística no ensino médio em programas brasileiros de pós-graduação. Os dados foram abordados segundo a análise de conteúdo, com categorias que emergiram da leitura dos trabalhos localizados. Os resultados dessa pesquisa mostraram uma descontinuidade das produções na área. Além disso, uma segunda pesquisa buscou Conhecer as atitudes de alunos de ensino médio sobre o Ensino de Estatística. Nessa etapa, foi utilizado um questionário, compostos por questões abertas e uma escala de Likert. A confiabilidade dos dados quantitativos foi estimada pelo método do alfa de Cronbach e os dados tratados segundo a estatística descritiva. Por fim, foi desenvolvido uma proposta de sequência didática a ser usada na disciplina de Matemática no Ensino Médio. O material está estruturado sob o enfoque CTS, a fim de oportunizar um aprendizado dinâmico dos conteúdos de estatística, explorando um tema estruturante e de formação crítico-reflexivo para o aluno
Synthesis of Novel Derivatives of Dissymmetric Bisarylidene of Tetrahydro-4Hpyran-4-one
Authors: Abaee M. Saeed , Afshinpoor Leila , Mojtahedi Mohammad M.
Published: February 2025

Several studies have reported that aldol condensation of various cyclic and acyclic ketones with aromatic aldehydes leads to the formation of symmetrical bisarylidene derivatives, while efficient synthesis of mono- and dissymmetric bisarylidenes is not very common and only a limited number of related reports are available. In the present work, a new one-pot method is designed and performed to synthesize dissymmetric bisarylidene derivatives of tetrahydro-4H-pyran-4-one heterocyclic system. Under the optimized conditions, the first aldehyde reacts with the starting ketone to give the corresponding monoarylidene. This monoarylidene can be either isolated as product 2 or used as the intermediate for a subsequent condensation with the second aldehyde to produce the respective derivative of 3. Both steps can take place in one pot, and high yields of either the monoarylidene intermediates or the final dissymmetric bisarylidene products would be obtained in short time intervals. The method is amenable to the synthesis of both mono- and dissymmetric bisarylidenes of the target compounds. New products of the reaction are fully characterized based on their 1H NMR, 13C NMR, IR, and mass spectroscopic data. The purity of these products is confirmed by elemental analyses. The results are promising to expand the outcome by applying the conditions to the synthesis of the respective derivatives of other heterocyclic systems.
Design of a System for Managing Complex Shift Patterns and Related Stress Levels for Blue Light Forces in the UK (Preprint)
Authors: Ayorinde Olumuyiwa , Dogan Huseyin , Adedoyin Festus Fatai , Jiang Nan , Bitters Fiona , Dempley Sara
Published: February 2025

UNSTRUCTURED

Blue Light services, such as police officers and emergency responders, face challenges in managing complex shift patterns and elevated stress levels. Despite these challenges, limited research explores how technology can help manage wellbeing while reducing stress. This paper presents the co-creation of a wellbeing app that integrates shift pattern system to support the work of blue-light forces. Data from interview and focus groups discussions with five participants, including police officers and shift management experts, were analysed using thematic coding. Results show that bulk creation of shifts, flexible start and finish times and manual editing of individual days are vital features for effective work schedule management. The research shows that integrating schedule management into a wellbeing app can deliver personalized health and wellbeing support, such as hydration reminders and relaxation techniques, based on users' specific shift schedules. In the UK, a case study of a home counties police force emphasized the need for user-friendly and privacy-conscious solution tailored to the complexity of Blue Light shift work. As a recommendation, designers, developers, blue light workers, and wellbeing professionals can collaborate to create an effective wellbeing solution that manages schedules and addresses occupational stress and shift-work-related challenges in high-stress occupations like policing.
One Digital Health - Wearable Technologies bridging the gap between Humans and Pets: A Viewpoint towards Healthcare 5.0 (Preprint)
Authors: Haghi Mostafa , Abani Samira , Khooyooz Soheil , Jahanjoo Anice , Rashidibajgan Samaneh , TaheriNejad Nima , Deserno Thomas , Volk Holger
Published: February 2025

UNSTRUCTURED

This viewpoint explores the transformative potential of integrating health monitoring
between humans and pets through wearable technology, underscoring the
interconnected nature of human-pet health. Wearable technologies mark a transition
in healthcare evolution, from paternalistic (Healthcare 1.0) to reactive (Healthcare
2.0), proactive (Healthcare 3.0), and data-integrated care (Healthcare 4.0). The next
stage, Healthcare 5.0, envisions the seamless integration of human and pet health
data, fostering a more holistic approach to disease prevention and management. This
paper examines the parallel evolution of human and pet health monitoring, assessing
current technologies and their potential to enhance both fields. We structure our
discussion around five key themes: (i) managing chronic conditions, (ii) monitoring
physical activity, (iii) behavioral and mental health, (iv) early disease detection, and
(v) clinical applications. Wearable technologies not only improve chronic disease
management but also enable early detection of zoonotic and emerging diseases,
contributing to public health strategies. Additionally, we highlight the reusability of
human wearable devices for pets, which can reduce costs and accelerate
implementation. This symbiotic approach fosters mutual benefits. The necessity of an integrated, linked platform is emphasized, as it enables real-time data analysis and
health insights, ultimately leading to better diagnostic accuracy, optimized treatment
plans, and enhanced quality of life for both humans and pets.
By repurposing wearable devices and advancing interconnected human-pet health
monitoring, we contribute to real-time data collection, patient-centered care,
predictive analytics, and preventive healthcare—ultimately accelerating the
realization of Healthcare 5.0.