bluuebunny/crossref_metadata_2025 huggingface dataset:
A Tool to Measure Nurses' Perceptions of Electronic Documentation: Exploratory Factor Analysis
Authors: Schenk Elizabeth C. , Brunelli Vanessa , Burduli Ekaterina
Published: March 2020

Background and Purpose

Electronic Health Records (EHRs) have been widely adopted in US hospitals. EHRs have changed workflow and time allocation and have broad impacts on staff. We adapted an existing instrument to measure nurses' perceptions of a newly adopted EHR.

Methods

The 11-item survey was administered to approximately 500 registered nurses in a mid-sized regional hospital in western US, with 153 responses received. Exploratory factor analysis (EFA) assessed the factor structure and Cronbach's α estimated internal consistency.

Results

A 3-factor model was retained through the EFA, and items were internally consistent (Cronbach's alpha for each subscale > .80).

Conclusions

Survey adaptation was iterative and resulted in a psychometrically sound and thematically relevant measure of nurses' EHR perceptions. Next steps include further psychometric evaluation and testing with additional samples.
Workplace Conflicts Among Emergency Department Nurses: Instrument Development and Psychometric Properties
Authors: Ganjizadeh Mohsen , Rahemi Zahra , Tafreshi Mansoureh Zagheri , Hajibagheri Ali , Ajorpaz Neda Mirbagher
Published: March 2020

Background and Purpose

Conflicts in nursing workplace are frequent and can be resolved by individuals or groups. The purpose of this study was to develop a valid and reliable measure for the Workplace Conflicts among Emergency Department Nurses (WCEDN).

Methods

A three-stage mixed methods study was conducted: (a) In-depth interviews with emergency department (ED) nurses were performed and themes were extracted from the data (b) Findings of the content analysis in combination with results of a literature review were examined, and preliminary instrument items were developed. The initial instrument comprised 50 items. (c) Content validity, face validity, content validity ratio, content validity index, and construct validity using exploratory factor analysis were performed.

Results

Subscales in the final instrument included Intrapersonal Conflict, Intragroup Conflict, Intergroup Conflict, and Causes of Conflict. Reliability of the instrument was .86, and the feasibility was 96.8%.

Conclusions

The final 40-item WCEDN demonstrated strong psychometric properties.
Psychometric Evaluation of the Caring Behaviors Inventory in Turkish Nurses and Patients
Authors: Gul Senay , Dinc Leyla
Published: March 2020

Background and purpose

Instruments developed specifically to measure nurse caring behaviors need to be assessed in different cultural contexts. The purpose was to translate the Caring Behaviors Inventory (CBI) into Turkish and evaluate its psychometric properties.

Methods

This was a methodological study with 356 nurses and 363 patients. Linguistic, content validity, and construct validity tested for the validity of scale. Internal consistency and test–retest were calculated for reliability of scale.

Results

Exploratory factor analysis identified 30 items that could be categorized under three factors. Cronbach's α for the CBI was .97 for nurses and .99 for patients.

Conclusions

The Turkish version of the CBI is a valid and reliable instrument for measuring caring behaviors.
Negative Behavior Among Healthcare Professionals: Integrative Review of Instruments
Authors: Layne Diana M. , Nemeth Lynne S. , Mueller Martina
Published: March 2020

Background

Behaviors that undermine a culture of safety pose a serious threat to the overall wellbeing of healthcare workers as well as to patient outcomes.

Purpose

The purpose of this integrative review is to compare reported psychometrics, feasibility, and identify commonalities among available instruments measuring negative behaviors among healthcare professionals.

Methods

Whittemore and Knafl's integrative review methods were used to analyze pertinent instruments designed to measure negative behaviors among healthcare professionals. Multiple computerized databases including CINAHL, MEDLINE, and Scopus databases were searched in the fall of 2017 without date restrictions.

Results

Violence, incivility, and bullying are the most frequently measured behaviors in healthcare workers, and a robust number of valid and reliable instruments are available.

Conclusions

To date a comprehensive review of psychometric properties and feasibility of administration is lacking. This review synthesizes the instruments measuring these behaviors, providing a resource for future research focused on mitigation and intervention strategies
A Practical Guide for Item Generation in Measure Development: Insights From the Development of a Patient-Reported Experience Measure of Compassion
Authors: Sinclair Shane , Jaggi Priya , Hack Thomas F. , McClement Susan E. , Cuthbertson Lena
Published: March 2020

Background and Purpose

Although various measure development guidelines exist, practical guidance on how to systematically generate items is nascent. This article provides practical guidance on item generation in measure development and the use of a Table of Specifications (TOS) in this process.

Methods

In addition to a review of the literature, the item generation process within an ongoing study to develop a valid and reliable patient-reported measure of compassion is provided.

Results

Consensus on an initial pool of 109 items and their response scale was achieved with the aid of a TOS.

Conclusions

Dynamic, experiential, and relational care constructs such as compassion lie at the heart of nursing. Practical guidance on item generation is needed to allow nurses to identify, measure, and improve compassion in research and practice.
#NotOkay: Stories About Abuse on Instagram and Twitter
Authors: Guidry Jeanine P.D. , Sawyer Ashlee N. , Burton Candace W. , Carlyle Kellie E.
Published: March 2020

Social media platforms like Twitter and Instagram have recently been used as venues for discussing abusive relationships and sexual violence. This study examines the ways in which social media users and how Twitter and Instagram users engaged with these posts by analyzing 500 Twitter and 500 Instagram posts focused on #NotOkay using a quantitative content analysis. There were marked differences between the posts on the two platforms as well as between engagement with these posts: Instagram overall elicited a higher median level of engagement than Twitter as well as more frequent expressions of social support; in addition, #NotOkay posts on Instagram were more likely to focus on specific acts of sexual assault. On Twitter, posts that included expressions of instrumental social support produced higher engagement. However, mentioning sexual assault produced higher engagement on both platforms. Providers and other interacting with sexual assault survivors should be aware of how these types of violence may be framed and expressed by different populations on different social media platforms.
Attitudes Toward Intimate Partner Violence in Muslim Society in Israel: Tragedy or Comedy
Authors: Sowan-Basheer Wafaa , Weinberg Michael
Published: March 2020

The purpose of the current study is to examine attitudes toward two types of violence—that perpetrated by men and that perpetrated by women—among a community of well-educated Muslims living in a Western country. Accordingly, two hypotheses were postulated, the first focusing on attitudes regarding men who perpetrate violence against women and the second focusing on attitudes toward women who perpetrate violence against men. The sample included 420 Muslim students who were studying in Arab institutions of higher education in northern Israel. The findings show that significant rates of both men and women think that “a woman hitting a man” might be seen as funny by their acquaintances. Meanwhile the vast majority of both men and women think that “a man hitting a woman” might be seen as sad by their acquaintances. However, the tendency to believe that such behavior would be viewed with sadness was stronger among women. The study helps to understand what the prevalent attitudes in society are, and has practical implications for raising public awareness around contexts of gender violence, as well as toward attitudes regarding violence among populations in transition from a traditional societal structure to a modern one.
Aggression in the Context of Partner Threat: The Role of Trauma Exposure
Authors: Mattern Alexandra C. , Marshall Amy D.
Published: March 2020

Trauma-related biased perception of threat, typically defined in terms of physical danger or harm, is associated with intimate partner aggression perpetration. Yet, it is unclear if such threat (a) functionally motivates aggression and (b) includes diverse forms of threat. Theory and limited research suggest that threats of rejection/abandonment and social dominance may be two distinct functional precipitants of aggression among trauma-exposed individuals. Sixty-four heterosexual couples (N = 128 individuals) selected for elevated symptoms of posttraumatic stress disorder in either partner were observed during conflict discussions. Small correlations between men's and women's engagement in threats of rejection/abandonment and social dominance suggest that they reflect distinct types of threat. Partners' rejection/abandonment threats and social dominance threats were more strongly associated with engagement in aggression among men with a relatively high frequency of trauma exposure, compared to men with a low frequency of trauma exposure and all women. Women with a high, relative to low, frequency of trauma exposure behaved more aggressively in the context of their partners' social dominance threats; women's aggression was not associated with the severity of their partners' rejection/abandonment threats. Results align with research suggesting that highly traumatized men's misperceptions of threat may motivate their aggression, and indicate that aggression may also be used in the context of accurately detected threat. Integration of methods to alter contextual and individual factors influencing aggression perpetration may improve intervention outcomes. Compared to individually-based interventions, conjoint couple interventions may be better poised to address maladaptive contextual processes that contribute to relationship aggression perpetration.
Hilmi Yavuz Şiirinde Geleneğin Bir Unsuru Olarak Türküler
Authors: ÖZ Mehmet
Published: March 2020

Edebiyatın gelişimi geçmişten bugüne uzanan kesintisiz bir çizgi olarak tanımlandığında ve edebiyata bu gözle bakıldığında elbette bir gelenekten söz edildiği açıktır. Çünkü bu noktada bu çizgi üzerindeki her durağın önceki duraklardan kimi izleri bünyesinde barındırdığı anlayışı ön plana çıkmaktadır. Geleneği önemseyen, ondan az veya çok faydalanmayı, bu iz üzerinden yürüyerek onu yeni bir bakış açısıyla geleceğe taşımayı kayda değer bir ölçü kabul eden şairler ve anlayışlar açısından gelenek vazgeçilemez bir kaynaktır. Elbette edebiyat tarihi içinde geleneği eleştiren, onu reddeden şair ve anlayışlar da kimi zaman var olagelmiştir. Geleneği reddedenlerin aksine Hilmi Yavuz, geleneği önemseyen, ondan faydalanarak onu şiirinin önemli bir kaynağına dönüştüren şairlerdendir. Yavuz; gerek klasik Türk şiirinden, gerek halk şiirinden, gerekse de Batı şiirinden faydalanmaya çalışanlardandır. Bu yüzden onun şiirlerinde geleneğin çeşitli izlerine çokça rastlanmaktadır. Bu makalede önce gelenek, gelenek ve Hilmi Yavuz ilişkisi üzerinde durulacak; daha sonra Hilmi Yavuz’un şiirlerine, geleneğin önemli unsurlarından biri olan türküler açısından yaklaşılacaktır.
Serviço Social no âmbito hospitalar
Authors: Vidal Michelli Ferrioli , Guilherme Rosilaine Coradini
Published: March 2020

O presente artigo foi elaborado a partir da experiência como assistente social residente junto ao Programa de Residência Multiprofissional Integrada em Saúde da Universidade Federal do Pampa, Campus Uruguaiana-RS, especificamente na ênfase Urgência e Emergência, Turma 2017-2019. Objetiva-se explicitar os atuais desafios à materialização das Atribuições Privativas e Competências Profissionais do Assistente Social em Unidades de Pronto Socorro no âmbito hospitalar, a fim de relacioná-los a identidade atribuída ao profissional de Serviço Social nestas unidades. A discussão tornar-se relevante na medida em que tenciona dar visibilidade ao trabalho do profissional de Serviço Social no âmbito hospitalar, especificamente em Unidades de Pronto Socorro. Neste sentido, o presente artigo foi elaborado com base em uma pesquisa documental, a qual se caracterizou como qualitativa de natureza exploratória, assim como se estruturou baseada no método dialético-crítico. Ao final do estudo foi possível evidenciar que o Assistente Social encontra diversos desafios em seu espaço sócio ocupacional. Tendo que lidar com a contradição das ações médico assistenciais e as ações voltadas as proposições do Sistema Único de Saúde –SUS, que faz com que alguns  profissionais que atuam em Unidade de Pronto Socorro não entendam o papel do profissional do Serviço Social. Em virtude disto o Assistente Social tem em seu contexto de trabalho uma realidade de resistência na defesa de sua identidade profissional, no intuito de materializar as suas Atribuições e Competências no âmbito hospitalar.
Emotional well-being and social support as important factors affecting the quality of life of parents of a child with cerebral palsy
Authors: Letovancová Katarína Molnárová , Slaná Miriam , Hromková Michaela
Published: March 2020

The birth of a child with cerebral palsy is an enormous challenge for the parents which has a direct impact on their quality of life. Therefore, we believe it is important to pay attention to this topic. To that end, we conducted research on the quality of life of parents of children with cerebral palsy in 2018. To achieve our goal, we applied quantitative research strategy and used a valid research tool, i.e. a standardized quality of life questionnaire – Family Quality of Life Scale ("FQOL"). The average score reached by respondents was 94.0918 points which indicates a higher quality of life in respondents than expected. The evaluation of the average score for each dimension of the scale showed that respondents scored the lowest in the "Emotional Well-Being" dimension (13.2551 points) and "Social Support" (15.6429 points). The research further confirmed that there were statistically significant differences in the quality of life of respondents depending on their age (t = -2.341, p = 0.021), marital status (F = 3.476, p = 0.019) and the territorial region (χ2 = 15.39, p = 0.031). A statistically significant relationship between the quality of life of respondents and the age of the child with cerebral palsy (0.288 **, p = 0.004) was confirmed. Despite a relatively high score that indicated a higher quality of life in respondents, the research identified two areas in which parents of children with cerebral palsy had a lower quality of life, namely, their emotional well-being and social support.
Etnia indígena Warao
Authors: González Muñoz Jenny
Published: March 2020

Los pueblos indígenas del Abya Yala a lo largo de la historia iniciada con la invasión colonizadora del siglo XV, han estado en constante periodo de resistencia cultural y social frente a los ataques directos e indirectos de la sociedad occidental que forma parte de su entorno. A partir de las luchas reivindicativas progresivamente han ganado espacio sobre todo en el aspecto jurídico, con la inclusión de leyes que velan tanto por la salvaguarda de estos pueblos como de sus bienes y manifestaciones culturales. No obstante, las emergencias contemporáneas relacionadas con crisis político-sociales y el crecimiento de actitudes discriminatorias hacia los pueblos ancestrales, los ha obligado a emprender una especie de diáspora interna y externa en procura de nuevas alternativas de vida. El presente trabajo pretende mostrar diversos aspectos del pueblo warao, oriundo del Delta del Orinoco, Venezuela, desde su entorno y contexto hasta la situación contemporánea como inmigrantes a Brasil desde la cual develamos algunas interrogantes con la intención de fomentar la reflexión.
Recursos públicos e a reabilitação da criança com implante coclear
Authors: Pereira Maria Rosa , Lopes Natália Barreto Frederigue , Mesquita Sonia Tebet de
Published: March 2020

Objetivo: Verificar a existência de recursos de apoio à reabilitação nas regiões de procedência dos pacientes em acompanhamento na Seção de Implante Coclear (IC) do Hospital de Reabilitação de Anomalias Craniofaciais da Universidade de São Paulo, e se estes estavam contribuindo com o processo de reabilitação e com a efetivação das políticas públicas. Método: O estudo envolveu análise documental de 87 prontuários de crianças usuárias de IC, com idade entre 1 a 12 anos incompletos. A caracterização dos sujeitos considerou o perfil socioeconômico e os recursos públicos disponibilizados. Resultados: A Faixa etária predominante foi de 42,5% entre 7 a 12 anos incompletos; 67% procedentes da região sudeste e 69% pertenciam à classe social Baixa Superior. A participação dos responsáveis na reabilitação foi dada como boa, 71,2% dos casos. Quanto aos recursos públicos disponíveis notou-se que: apenas 12,6% tinham o acesso a benefícios assistenciais; a maioria estava inserida na rede pública de ensino; utilizando do Tratamento Fora do Domicílio de forma parcial para o acompanhamento no serviço e 58,7% realizavam terapias fonoaudiológicas via Sistema Único de Saúde. Conclusão: constatou-se a existência e acesso aos recursos públicos, no entanto sem contemplar qualitativamente as exigências da reabilitação para as crianças usuárias de IC.
Editorial: Serviços Social & Saúde: aspectos estruturais e conjunturais
Authors: Joazeiro Edna Maria Goulart
Published: March 2020

O Conselho Editorial e o Conselho Científico do periódico Serviço Social & Saúde apresentam à Comunidade Científica e aos leitores um novo exemplar no ano em que se comemora o décimo oitavo ano de publicação ininterrupta do periódico. O volume foi organizado com base nas discussões oriundas do campo da Saúde, que são inelutavelmente atravessadas pelas demais políticas sociais e pelos desafios relativos à ampliação das desigualdades no acesso ao direito e a redução do financiamento das políticas sociais públicas. Nessa perspectiva, a publicação contribui para pensar como aspectos estruturais e conjunturais podem colocar em risco o direito e o acesso às políticas públicas universais, historicamente, construídas. Aproveitamos o momento de encontro com os leitores para explicitar que a partir do ano de 2019 o periódico adotou a periodicidade de publicação contínua (PC) em consonância com a necessidade de dar ampla visibilidade às publicações num tempo marcado pela premência da produção e da socialização do conhecimento.
Tinjauan Penerapan Sita Jaminan (Conservatoir Beslag) Dalam Tindak Pidana Korupsi
Authors: Mahardika Muhammad Dzakir Gusti
Published: March 2020

Jaksa sebagai pelaksana dari putusan pengadilan sering mendapati kesulitan untuk merampas hasil tindak pidana yang merugikan keuangan negara dikarenakan aset yang hendak dirampas tidak ditemukan. Penyebabnya adalah sempitnya rezim hukum benda yang dapat dikenakan penyitaan dan juga ada kecendrungan bagi Terpidana untuk tidak membayar uang pengganti. Dengan demikian, diperlukan upaya maupun metode baru yang dianggap efektif untuk meningkatkan nilai aset yang berhasil dikembalikan kepada negara. Dengan diterapkannya conservatoir beslag yang ada pada ranah hukum perdata ke dalam ranah hukum pidana, diyakini oleh sarjana maupun praktisi hukum dapat menjadi solusi yang dibutuhkan untuk mengatasi kendala asset recovery. Akan tetapi, terdapat perbedaan-perbedaan yang mendasar dalam karakteristik hukum perdata dan hukum pidana, yang tentunya tidak dapat membuat penerapan dapat dilakukan secara serta merta. Oleh karena itu, bentuk kualifikasi conservatoir beslag agar dapat diterapkan dalam ranah hukum pidana juga perlu dianalisis lebih lanjut. Dalam menjawab permasalahan tersebut, penelitian ini menggunakan tipe penelitian yuridis normatif dengan pendekatan melalui peraturan perundang-undangan, pendekatan konsep, pendekatan kasus, serta pendekatan perbandingan. Penelitian ini berkesimpulan bahwa conservatoir beslag sepatutnya dipertimbangkan untuk dapat diterapkan di Indonesia mengingat adanya hukum internasional, sumber hukum negara asing, yurisprudensi Mahkamah Agung yang mendorong diterapkannya conservatoir beslag guna meningkatkan efektivitas asset recovery di Indonesia.
Pulsa Telepon Seluler sebagai Alat Pembayaran
Authors: Zaki Muhammad
Published: March 2020

Penetrasi Kartu Kredit yang rendah mengakibatkan operator jasa telekomunikasi untuk memberikan layanan pembayaran menggunakan pulsa telepon seluler di Aplikasi Google Play. Terdapat empat pelaku usaha jasa telekomunikasi yang menyediakan alternatif pembayaran menggunakan pulsa telepon seluler yaitu PT. Telkomsel, PT. Indosat, PT. XL dan PT Hutchison 3 Indonesia (Tri). Metode yang digunakan oleh operator jasa telekomunikasi untuk menjadikan pulsa telepon seluler alat pembayaran di aplikasi Google Play Store adalah metode pemotongan pulsa. Transaksi jual beli di Google Play Store dengan menggunakan pulsa telepon seluler mempermudah masyarakat yang ingin membeli perangkat lunak berbayar dan fitur berbayar yang ditawarkan di Google Play Store tanpa harus menggunakan kartu kredit. Penggunaan pulsa telepon seluler pada transaksi jual beli ini menimbulkan pertanyaan baru dikarenakan operator telepon seluler yang awalnya tidak menyediakan jasa pembayaran selain uang elektronik, seperti yang diatur pada Peraturan Bank Indonesia Nomor 20/6/PBI/2018 tentang Uang Elektronik, menerbitkan pulsa telepon seluler sebagi alat pembayaran. Sehingga penelitian lebih lanjut terkait karakteristik pulsa telepon seluler dan perlindungan hukum pengguna pulsa telepon seluler terhadap operator telepon seluler perlu dilakukan. Penelitian tersebut menyimpulkan bahwa pulsa telepon seluler bukan merupakan bukan merupakan uang elektronik dan belum ada legal framework yang tepat untuk mengakomodir karakteristik dari pulsa tersebut.
Perlindungan Hukum Pihak Pemberi Pinjaman pada Layanan Pinjaman Pendidikan Berbasis Teknologi Informasi terhadap Risiko Gagal Bayar
Authors: Rahmahafida Nadia Intan
Published: March 2020

Bisnis Finansial Teknologi kini sangat marak di Indonesia, khususnya layanan peer to peer lending. Dalam perkembangannya, hadir pula layanan peer to peer lending yang dikhususkan untuk dana pendidikan. Tujuan hadirnya layanan peer to peer lending yakni untuk mempermudah penerima pinjaman dalam mengajukan pinjaman tanpa tatap muka. Akan tetapi, dalam pelaksanaan peer to peer lending, pemberi pinjaman memiliki kemungkinan mengalami risiko gagal bayar yang diakibatkan oleh penerima pinjaman, sehingga perlu dianalisis mengenai hubungan hukum antara para pihak dalam perjanjian pinjaman untuk menentukan pihak yang bertanggungjawab. Lebih lanjut lagi, bentuk perlindungan hukum preventif dan represif bagi pihak pemberi pinjaman terhadap risiko gagal bayar perlu dianalisis lebih lanjut. Dalam menjawab permasalahan tersebut, penelitian ini menggunakan tipe peneilitian doktrinal dengan pendekatan melalui pendekatan peraturan perundang-undangan dan pendekatan konsep. Penelitian ini berkesimpulan bahwa pada perjanjian peer to peer lending, terdapat beberapa pihak yang terlibat yakni penyelenggara, pemberi pinjaman, dan penerima pinjaman serta penjamin apabila ada yang dibuat secara elektronik melalui sistem elektronik. Dalam hal terjadi gagal bayar, pada perjanjian pinjaman terdapat upaya-upaya yang dapat ditempuh oleh pemberi pinjaman. Lebih lanjut lagi, pada perlindungan hukum preventif bagi pemberi pinjaman, penyelenggara wajib untuk melakukan evaluasi terkait dengan data penerima pinjaman. Sedangkan terkait dengan perlindungan hukum represifnya, terdapat upaya penyelesaian sengketa secara damai dan penyelesaian sengketa di Pengadilan.
Upaya Diversi oleh Penuntut Umum Dalam Undang-Undang Nomor 11 Tahun 2012 Tentang Sistem Peradilan Pidana Anak
Authors: Bemba Riana Kusuma Putri
Published: March 2020

Artikel ini membahas mengenai diversi oleh Penuntut Umum. Tipe penulisan penelitian ini adalah reform-oriented research, dengan menggunakan pendekatan undang-undang dan pendekatan konseptual. Penelitian ini akan membahas mengenai: (1) ratio legis dari ketentuan Pasal 42 Undang-Undang Nomor 11 Tahun 2012 tentang Sistem Peradilan Pidana Anak; dan (2) akibat hukum dari diversi oleh Penuntut Umum yang lewat batas waktu 7 (tujuh) hari. Dari penelitian ini, disimpulkan bahwa ratio legis dari Pasal 47 UU SPPA berangkat dari pemahaman bahwa UU SPPA merupakan hukum pidana khusus, yang mana mengatur secara khusus proses peradilan pidana anak. Kekhususan tersebut terlihat dengan adanya keadilan restoratif, yang menjadi jiwa dan dasar dari ketentuan-ketentuan dalam UU SPPA yang menyimpang undang-undang umum, yaitu KUHAP. Salah satu ketentuan tersebut adalah dengan adanya diversi, dimana Pasal 47 mengatur diversi oleh penuntut umum. Karena adanya perbedaan penyelesaian perkara pidana dalam KUHAP dan Undang-Undang Nomor 11 Tahun 2012 tentang Sistem Peradilan Pidana Anak., mengakibatkan diversi yang wajib diupayakan oleh Penuntut Umum dapat melebihi batas waktu yang diatur dalam Pasal 42Undang-Undang Nomor 11 Tahun 2012 tentang Sistem Peradilan Pidana Anak tersebut, yaitu 7 (tujuh) hari. Akibat hukum dari diversi oleh Penuntut Umum yang lewat batas waktu 7 (tujuh) hari adalah batal demi hukum.
Perlindungan Hukum bagi Pemegang Kartu Kredit Atas Fasilitas Tambahan Asuransi yang Diberikan Oleh Penerbit Kartu Kredit
Authors: Kurniansyah Ryan
Published: March 2020

Asuransi menurut Pasal 246 KUHD adalah suatu perjanjian dengan mana seseorang mengikatkan diri kepada seseorang tertanggung, dengan menerima suatu premi untuk memberikan suatu pergantian kepadanya karena suatu kerugian, kerusakan, atau kehilangan keuntungan yang diharapkan, yang mungkin diderita karena suatu peristiwa tak menentu. Asuransi dibedakan menjadi 3 golongan yaitu: asuransi kerugian, asuransi jiwa dan asuransi sosial. Asuransi digunakan sebagai fasilitas tambahan terhadap pemegang kartu kredit yang diberikan kepada nasabah melalui telemarketing dari perusahaan asuransi yang menjadi mitra bank, Peraturan Bank Indoesia Nomor 14/2/PBI/2012 Tentang Penyelenggaraan Kegiatan Alat Pembayaran Dengan menggunakan kartu menjelaskan mengenai kartu kredit yaitu alat pembayaran dengan menggunakan kartu yang dapat digunakan untuk melakukan pembayaran atas kewajiban yang timbul darisuatu kegiatan ekonomi, termasuk transaksi pembelanjaan dan/atau untuk melakukan penarikan tunai, dimana kewajiban pembayaran pemegang kartu dipenuhi terlebih dahulu oleh acquirer atau penerbit, dan pemegang kartu berkewajiban untuk melakukan pembayaran pada waktu yang disepakati baik dengan pelunasan secara sekaligus (charge card) ataupun dengan pembayaran secara angsuran.Perlindungan hukum bagi pemegang kartu kredit terhadap klaim atas penggunaan fasilitas tambahan dalam kartu kreditpoin ke-7 Surat Edaran Bank Indonesia Nomor 14/17/DASP Tahun 2012 menyatakan bahwabank dilarang untuk memberikan fasilitas tambahan yang dapat berdampak pada penambahan biaya yang ditanggung oeh nasabah tanpa persetujuan tertulis dari nasabah.
Different Approaches of Continuous Fascial Iliaca Compartment Block Under Ultrasound-Guidance for Hip Arthroplasty: Short axis vs long axis in-Plane Techniques
Authors: Ahmed Ali Ebshena  , Mei Wei
Published: March 2020

Continuous Fascia iliaca compartment block provides effective analgesia by effective blockade of the femoral and lateral femoral cutaneous (LFC) in patients undergoing hip orthopedic surgeries. We compared analgesic effect of ultrasound-guided continuous fascia iliaca compartment block using either a short-axis in-plane technique or a long-axis in-plane technique for patients undergoing hip arthroplasty.In this prospective double-blind study, twenty-six ASA- I and II patients undergoing hip orthopedic surgeries were enrolled and randomly assigned to receive continuous fascia iliaca compartment block with either a short axis in-plane or a long-axis in- plane technique. The perineural catheter was attached to an electronic infusion pump. Ropivacaine 0.2% was administered through the catheter for 48 hours (4 mL/h). The primary outcome was ropivacaine consumption within 48h in the two groups. Secondary outcomes included the procedural time, success rate of block, postoperative pain score evaluated by NRS score at rest and movement. There was no significant difference in the consumption of ropivacaine during the 48 postoperative hours (P>0.05). Short-axis in-plane group need less procedural time for catheterization insertion than long-axis group. Compared with the short-axis in-plane technique, long-axis in-plane continuous fasicia iliaca compartment block had no ropivacaine-sparing effect on patient-controlled analgesia for hip arthroplasty.
Physical-Chemical Characterization and Thin Layer Chromatographic Comparison of a Local Propolis with the Mangifera indica Resin
Authors: Dailen Guanche Gallardo  , Mario Fajardo  , Yaneisy Naranjo Alonso  , Lilian San Martín Echemendía  , Jam Montalvan Copello
Published: March 2020

Mango (Mangifera indica) is an abundant tree of Cuban flora that is known for many healing properties and a deposit of bees as a source of raw materials for the propolis production. This work aimed to determine if the resin of mango felled bark was used by honeybees in the elaboration of a specific type of propolis. This could be possible by qualitatively comparison of its samples with the mango resin and the quality of this propolis through its physicochemical characteristics. To do this, propolis was collected and hydroalcoholic extracts were prepared. From this, botanical origin was determined by the technique of thin layer chromatography. Humidity, oxidation index, wax, resin and mechanical mixtures were evaluated from raw material. Results demonstrated that the samples of propolis collected presented a chromatographic profile similar to mango resin. In the samples of propolis, it was determined that quercetin and mangiferin are present in their qualitative composition of secondary metabolites. On the other hand, the mango propolis satisfies the requirements established by international regulations for good quality propolis in terms of humidity, oxidation index and mechanical mixtures.
Analysis of Some Hematological and Biochemical Markers in Women Cancer Patients Receiving Doxorubicine Chemotherapy
Authors: Boulaares Islam  , Guemari Imane Yousra  , Derouiche Samir
Published: March 2020

The goal of this study is to evaluate the effect of Doxorubicine chemotherapy on some biochemical and hematological markers in female cancer's patients. 22 cases of women cancer and control were chosen, Blood samples were collected from them and lipid profile, creatinine, urea levels and enzyme activities were measured. Also, erythrocyte and leucocyte line levels in blood was measured. Results of biochemical parameters revealed that a significant increase in serum lipid profile, creatinine level, LDH, GOT, GPT and GGT activities and no significant change in serum urea level in women with cancer compared to controls. On the other hand,  Results of the haematological analysis show that RBC, HGB, HCT and lymphocyte (p <0.01) level are significant decreased in patients compared to control group and no significant change in WBC, Neutrophil , Monocyte , Eosinophil and basophile in patients compared to control group. In conclusion, the present study suggests that doxorubicin affect some biochemical and hematological marker of cardiac function indicating the cardiotoxic as a side effect of this treatment in cancer patients.
Interpreting f-Statistics and Admixture Graphs: Theory and Examples
Authors: Lipson Mark
Published: March 2020

A popular approach to learning about admixture from population genetic data is by computing the allele-sharing summary statistics known as f-statistics. Compared to some methods in population genetics, f-statistics are relatively simple, but interpreting them can still be complicated at times. In addition, f-statistics can be used to build admixture graphs (multi-population trees allowing for admixture events), which provide more explicit and thorough modeling capabilities but are correspondingly more complex to work with. Here, I discuss some of these issues to provide users of these tools with a basic guide for protocols and procedures. My focus is on the kinds of conclusions that can or cannot be drawn from the results of f4-statistics and admixture graphs, illustrated with real-world examples involving human populations.
A Putative Prophylactic Solution for COVID-19: Development of Novel Multiepitope Vaccine Candidate against SARS‐COV‐2 by Comprehensive Immunoinformatic and Molecular Modelling Approach
Authors: Rehman Hafiz Muzzammel , Mirza Muhammad Usman , Saleem Mahjabeen , Froeyen Matheus , Ahmad Sarfraz , Gul Roquyya , Aslam Muhammad Shahbaz , Sajjad Muhammad , Bhinder Munir Ahmad
Published: March 2020

The outbreak of 2019-novel coronavirus (SARS-CoV-2) that causes severe respiratory infection (COVID-19) has spread in China, and the world health organization declared it pandemic. However, no approved drug or vaccines are available, and treatment is mainly supportive and through a few repurposed drugs. In this urgency situation, development of SARS-CoV-2 based vaccines is immediately required. Immunoinformatic and molecular modelling are generally used time-efficient methods to accelerate the discovery and design of the candidate peptides for vaccine development. In recent years, the use of multiepitope vaccines is proved to be a promising immunization strategy against viruses and pathogens, which induce more comprehensive protective immunity. The current study demonstrated a comprehensive in-silico strategy to design stable multiepitope vaccine construct (MVC) from B-cell and T-cell epitopes of essential SARS-CoV-2 proteins with the help of adjuvants and linkers. The integrated molecular dynamics simulations analysis revealed the stability of MVC and its interaction with human Toll-like receptors (TLRs), which trigger an innate and adaptive immune response. Later, the in-silico cloning in a known pET28a vector system also estimated the possibility of MVC expression in E. Coli. Despite this study lacks validation of this vaccine construct in terms of its efficacy, the current integrated strategy encompasses the initial multiple epitope vaccine design concepts. After validation, this MVC can present to be a better prophylactic solution against COVID-19.
Empirical Evidence Demonstrating Injection Containment and Absence of Injection-Induced Fracturing, Wilmington Oil Field Case Study
Authors: Kellogg Ryan P. , Mercier David
Published: March 2020

Waterfloods in California operate under the US Environmental Protection Agency's Class II underground injection control regulations, which are tasked with the protection of underground sources of drinking water (USDW) within the state. A key aspect of this regulatory framework is the operation of water injection wells under a maximum allowable surface pressure (MASP) to ensure that injected water does not induce and/or extend formation fractures that could create a potential conduit connecting the hydrocarbon zone with identified USDWs. Determination of the MASP for individual injection wells has typically been calculated using a step rate test (SRT), but this method has been shown to be inappropriate for multilayered, unconsolidated sandstone reservoirs (Ershaghi and Ershaghi 2018), which are prevalent in Wilmington Field. To avoid the potential for misinterpretation of SRTs to imply fracturing in this context, in this paper we summarize the evidence demonstrating both the effective geologic containment of injected fluid in the hydrocarbon-bearing zones and the absence of injection-induced fracturing. In addition, a series of field tests were conducted to assess the stress sensitivity of the Wilmington reservoirs and investigate in-situ changes in the reservoir at higher injection pressures by combining multirate injection tests with injection profile surveys. These results provide data supporting the noted challenges associated with MASP determination for multilayered, unconsolidated reservoirs. In this paper, we give operators and regulators working in these types of fields a framework for assessing both injection containment and injection-induced fracturing that account for the unique properties of these formations.
Coiled Tubing Adaptability in the Development of Shale Plays: 81 Days of Continuous Operation in the First UK Land Gas Shale Project
Authors: Fernandez C Diego A. , Franco D. Ernesto , Villagrana P. Carlos , Machado Ángel
Published: March 2020

This paper presents the procedures, best practices and results of a coiled tubing project on the first unconventional completion using the multistage fracturing technique onshore in the United Kingdom, to achieve commercial gas flow rates from the inland shale formations. The main goal of the coiled tubing operations was to deliver multiple hydraulic fracturing stages through the CT/tubing annulus in a single run; but the versatile technology was used for a wide range of intervention activities during the project.
Association of built environment with physical activity and among Chinese women
Authors: Sun Yuliang , He Chunzhen , Cheng Zhiwei , Hou Jianyu , Sun Fangjun , Zhang Xinxin , Zhu Wenfei
Published: March 2020

The authors have withdrawn this preprint from Research Square
Nilotinib, a Discoidin domain receptor 1 (DDR1) inhibitor, induces apoptosis and inhibits migration in breast cancer
Authors: Yu Shufang , Wang Shuang , Xie Yanping , Bao Aina , Li Jing , Ye Tingting , Yang Chu , Lin Bin , Yang Minghua
Published: March 2020

Background: Overexpression of Discoidin domain receptor 1(DDR1) is known to enhance the malignancy of breast cancer considerably. This study reports the identification of a potent DDR1 inhibitor, Nilotinib for the treatment of breast cancer.
Methods: MTT assay was used to evaluate the inhibitory activity of Nilotinib and meantime we used flow cytometry to evaluate the pro-apoptotic activity of Nilotinib against MCF-7 and MDA-MB-231. Expression of DDR1 was manipulated in MCF-7 cell lines with low level DDR1 expression by transfecting with plasmids containing by shRNA. The effect of DDR1 or treatment with Nilotinib on cell migration was assayed. The expression of p-DDR1, DDR1, p-ERK1/2, ERK1/2 and E-cadherin，Vimentin, Snail1 were detected by western blot and immuno-fluorescent staining .
Results: Nilotinib against MCF-7 (IC 50 =0.403 μM) and MDA-MB-231 (IC 50 =0.819 μM) and also indicated induced apoptotic cell death after co-cuturing with Nilotinib (500 nM), apoptosis rate is 29.60 % ± 2.19% and 18.75 % ± 2.30% respective ly. Moreover, Nilotinib effectually blocked cellular migration of MCF-7. Interestingly, Knock-down DDR1 could significantly block the migration of breast cancer, meantime the sensitivity of Nilotinib to MCF-7 was reduced.
Conclusion: Targeting DDR1 therapeutically could potentially affect survival and influence metabolism in breast cancer, and Nilotinib could as a candidate for the treatment of breast cancer.
Adipose-Derived Mesenchymal Stem Cells Attenuate Acute Lung Injury Through Regulation of the Gut Microbiota in Septic Rats
Authors: Sun Jun-Yi , Ding Xian-Fei , Liu Shao-Hua , Duan Xiao-Guang , Liang Huo-Yan , Sun Tong-Wen
Published: March 2020

Background: We hypothesized that adipose-derived mesenchymal stem cells (ADMSCs) may ameliorate sepsis-induced acute lung injury (ALI) by increasing or decreasing microorganism populations in the gut microbiota, such as that of Firmicutes and Bacteroidetes.Methods: A total of 60 male adult Sprague-Dawley (SD) rats were separated into three groups: the sham control (SC) group, the sepsis induced by cecal ligation and puncture (CLP) group, and the ADMSC treatment (CLP-ADMSCs) group, in which rats underwent the CLP procedure and then received 1 × 106 ADMSCs. Rats were sacrificed 24 hours after the SC or CLP procedures. To investigate the relationship between sepsis-induced ALI and the gut microbiota, rat lungs were histologically evaluated using hematoxylin and eosin (H&E) staining, serum levels of pro-inflammatory factors were detected using enzyme-linked immunosorbent assay (ELISA), and fecal samples were collected and analyzed using 16S rDNA sequencing.Results: The serum levels of inflammatory cytokines, tumor necrosis factor (TNF)-α and interleukin (IL)-6, were significantly increased in rats after the CLP procedure, but were significantly decreased in rats treated with ADMSCs. Histological evaluation of the rat lungs yielded results consistent with the changes in IL-6 levels among all groups. Treatment with ADMSCs significantly increased the diversity of the gut microbiota in rats with sepsis. The principal coordinates analysis (PCoA) results showed that there was a significant difference between the gut microbiota of the CLP-ADMSCs group and that of the CLP group. In rats with sepsis, the proportion of Bacteroides related to energy consumption and Escherichia–Shigella related to lipopolysaccharide production increased, and the proportion of Akkermansia related to the regulation of intestinal mucosal thickness and the maintenance of intestinal barrier function decreased. Furthermore, the proportion of Firmicutes related to energy storage, such as Verrucomicrobia, decreased. These changes in the gut microbiota break the energy balance, aggravate inflammatory reactions, reduce intestinal barrier functions, and promote the translocation of intestinal bacteria. Intervention with ADMSCs increased the proportion of beneficial bacteria, reduced the proportion of harmful bacteria, and normalized the gut microbiota, thus, improving the sepsis-induced ALI.Conclusions: Therapeutically administered ADMSCs may improve CLP-induced ALI by regulating the gut microbiota, providing a potential mechanism by which mesenchymal stem cells treat sepsis.
Interventions Carried Out In Primary Health Care To Deal With Overweight And Obesity - A Scoping Review
Authors: Souza Rafaela , Davies Vanessa Fernandes , Silva Rosana Mara da , Ferreira Joel Carlos Valcanai , Nickel Daniela Alba , Calvo Maria Cristina Marino , Lacerda Josimari Telino de
Published: March 2020

Introduction and objectives: overweight and obesity are important public health problems which have a negative impact on the quality of life of individuals and on health systems around the world. Primary Health Care (PHC) becomes a crucial health care model for addressing the problem of overweight and obesity. This study presents the protocol of a scoping review that aims to describe the interventions related to dealing with overweight and obesity in PHC, identifying the obstacles and facilitators for their implementation.Methods and Analysis : the scoping review protocol presented was based on the recommendations of the Prisma Extension for Scoping Reviews (PRISMA-SCR), as well as the framework proposed by Arksey and O’Malley. The research questions were elaborated by a multidisciplinary team of researchers, graduate students and professors belonging to a research group working in the area of ​​health policy and program evaluation. In addition, two pilot studies were carried out to refine the questions and to improve the online article research and consequently the protocol. The bibliometric databases that will be used are PUBMED, EBSCO, SCOPUS, WEB OF SCIENCE; using specific keywords for each database to orientate the search for original articles written in English. Every step of the research will be carried out by two researchers working independently. The steps include: searching the selected databases with the keywords; reading the title and summary of the articles found; reading the selected articles in full and transferring the data extracted from the articles to a table; a thematic analysis of the results.Ethics and Dissemination : the results of the scoping review will be published in a scientific journal and presented at conferences and other scientific events. It is hoped that the presentation and discussion of the findings of the scoping review proposed in this protocol can help researchers, health professionals and planners of PHC policies and programs to identify gaps in the literature, to reflect upon the experiments conducted around the world, and to explore possibilities for adapting successful interventions to varied geographical and cultural contexts.
SCO-AN:Improve Secrecy Capacity for Secure Transmission Using Power Allocation
Authors: Gu Yebo , Wu Zhilu , Yin Zhendong , Huang Bowen
Published: March 2020

Artificial noise(AN) is a core technique in physical layer security field which has been widely studied.AN reduces the channel capacity of eavesdroppers without affecting the channel capacity of the communicator so that AN can increase secrecy capacity.Secrecy capacity is defined as channel capacity of the communicator minus channel capacity of eavesdroppers.The AN is prohibited from affecting the channel capacity of the legal receiving channel. This condition brings good performance to AN as well as limitations.Recently, the secrecy capacity optimization artificial noise (SCO-AN) is proposed to increase the secrecy capacity more effectively.SCO-AN can reduce the channel capacity of the communicator to a small extent while greatly reducing the channel capacity of the eavesdropper. So, SCO-AN can further expand the secrecy capacity on the basis of AN. Due to the limitation of transmit power, SCO-AN cannot be added indefinitely, so it is an important issue to increase the secrecy capacity as much as possible under a certain power limit.In this paper, a secrecy capacity function with SCO-AN added under certain power constraints is established.Because this function is non-convex, the traditional convex optimization algorithm cannot be applied. A sequence quadratic program(SQP) is adopted to solve this power allocation problem.Simulation results show that SQP can effectively improve the secrecy capacity under a certain power limit.
Study on long noncoding RNA in enterovirus 71-induced severe hand-foot-mouth disease
Authors: Fang Fang , yi He , feng Xu
Published: March 2020

Background: To identify the critical type of severe hand-foot-mouth disease (HFMD) in early stage, long noncoding ribonucleic acid (LncRNA) microarray was used to screen specific LncRNA and to predictpossible pathogenesis and target genes of HFMD. Methods: Twenty cases of EV71-induced severe HFMD were collected in Children’s Hospital of Chongqing Medical University from September 2015 to September 2016. LncRNA microarray was used to analyze the expression of LncRNA and mRNA in peripheral blood of children between severe type and critical type, and then verify the validity by real-time polymerase chain reaction. Bioinformatic methods were used to investigate differentially expressed mRNA by gene ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis. Results: We obtained differentially expressed profiles of LncRNA and mRNA from peripheral blood of children with EV71-induced severe HFMD, and the number of LncRNA was 1949, the total mRNA profiles were 1422. GO analysis found that differentially expressed mRNAs were involved in the processes of immune response, immune defense, nucleic acid metabolism, and protein and molecule binding. KEGG analysis revealed that the differentially expressed mRNAs were involved in the p53 signaling pathway, NOD-like receptor signaling pathway, osteoblast differentiation, and so on. The target gene SLPI was closely related to the critical type of severe HFMD by cis/trans target gene prediction, and the pathogenic processes was regulated by LncRNA NR_038337. Conclusion: Since differentially expressed LncRNAs and mRNAs are present in severe HFMD, our findings provide a new method to explore the pathogenesis of the critical type of severe HFMD, andfurther study on specific LncRNA and target genes in critical type has great significance for diagnosis and treatment of severe HFMD. Keywords: Long noncoding RNA; Enterovirus 71; Severe hand-foot-mouth disease; Target gene Trial registration:ChiCTR-DCD-15007192.Registered 8 October,2015, http://www.chictr.org.cn/ ChiCTR-DCD-15007192