bluuebunny/crossref_metadata_2025 huggingface dataset:
Charging electric cars as a way to increase the use of energy produced from RES
Authors: Małek Arkadiusz , Caban Jacek , Wojciechowski Łukasz
Published: March 2020

The article contains an analysis of charging electric cars as a way to increase the use of energy produced from a photovoltaic system. A photovoltaic system is described, consisting of two micro installations, with a power output of up to 40 kWp each, supplying two sectors of the building of the Lublin Science and Technology Park. An internet platform for monitoring the operation of a photovoltaic system is presented. Next, an innovative system for monitoring, consumption and production analysis of electric energy in individual building sectors is described. A surplus of energy produced in one of the sectors was found. It was proposed that this excess energy would be used to charge electric vehicles. An analysis of the surplus power generated by the photovoltaic system in excess of the energy consumed by the building sector was used to determine the power available to the wall charger. The surplus of energy produced was used for calculations related to the amount of charging the electric vehicle required and the cost of traveling 100 km. Charging an electric car not only provides a faster return on investment in the installation, but also presents drivers with a very ecological and economical transport solution.
The oxidative coupling between benzaldehyde derivatives and phenylacetylene catalyzed by rhodium complexes via C-H bond activation
Authors: Zhao Xinyi , Jia Hongge , Wang Qingji , Song Heming , Tang Yanan , Ma Liqun , Shi Yongqiang , Yang Guoxing , Wang Yazhen , Zang Yu , Xu Shuangping
Published: March 2020

This paper reports the use of rhodium (Rh) catalysts for the oxidative coupling reaction between phenylacetylene and benzaldehyde derivatives via C-H bond activation. These reactions were catalyzed by Rh(l-amino acid)(cod) (the l-amino acid is l-phenylalanine, l-valine or l-proline; cod is 1,5-cyclooctadiene) to obtain chromones in 12.7–88.3% yield. These new Rh catalysts have excellent activity for the coupling reaction between phenylacetylene and different benzaldehyde derivatives. It was found that the electronic effects of the benzaldehyde derivative substituent affected the reaction yield, which is in accordance with the proposed mechanism.
The effects of circuit resistance training on plasma progranulin level, insulin resistance and body composition in obese men
Authors: Safarzade Alireza , Alizadeh Hamid , Bastani Zainab
Published: March 2020

Background

Progranulin (PGRN) is implicated in obesity and insulin resistance (IR). The aim of this study was to evaluate the effects of 8 weeks of circuit resistance training (CRT) on plasma PGRN, IR and body composition in obese men.

Materials and methods

Twenty-eight healthy obese men [age: 36 ± 7.7 years, body weight (BW): 96.4 ± 15.6 kg, body mass index (BMI): 32.4 ± 4.5 kg/m2] completed the study. Subjects were randomly assigned to two groups of control and training. Subjects in the training group underwent training for 8 weeks, 3 times a week. Blood samples and anthropometric characteristics were taken before the commencement of the exercise protocol and 72 h after the last training session. The homeostatic model assessment of insulin resistance (HOMA-IR) was used to measure IR.

Results

BW, BF%, BMI, waist-hip ratio (WHR), HOMA-IR and plasma PGRN levels except lean body mass (LBM) were significantly reduced in the training group (p < 0.05). Additionally, except for LBM, subjects in the training group had significantly decreased BW, BF%, BMI, WHR, HOMA-IR and plasma PGRN levels compared to changes in those in the control group (p < 0.05). Significant correlations were found between the changes in plasma PGRN and the changes in insulin, HOMA-IR and BMI (p < 0.05).

Conclusions

The findings showed that 8 weeks of CRT improved body composition and IR which were accompanied by reduced plasma PGRN levels. This study suggests that CRT has the potential for obese individuals to counteract obesity-associated health impairments.
Utility of MR proton density fat fraction and its correlation with ultrasonography and biochemical markers in nonalcoholic fatty liver disease in overweight adolescents
Authors: Netaji Arjunlokesh , Jain Vandana , Gupta Arun Kumar , Kumar Udit , Jana Manisha
Published: March 2020

Background

Clinical or biochemical markers that have good correlation with magnetic resonance proton density fat fraction (MR PDFF) can be used as simple tools for the screening for nonalcoholic fatty liver disease (NAFLD) and in determining the degree of fatty infiltration of the liver. The objective of this study was to determine the degree of relationship between MR PDFF and ultrasonography (USG) grades of fatty liver, and clinical and biochemical parameters of adolescents and to determine the sensitivity and specificity of USG for diagnosis of NAFLD.

Methods

This prospective study included 34 overweight adolescents (mean age, 12.1 ± 1.5 years; range, 10–15.1 years; 10 girls and 24 boys) who underwent both USG and magnetic resonance imaging (MRI). Correlation analysis was performed between MR fat fraction and USG grades of fatty liver, and clinical and biochemical parameters of fatty liver disease.

Results

MR fat fraction had a moderate positive correlation with serum alanine transaminase (ALT) and aspartate transaminase (AST) (ρ = 0.634, p < 0.001, ρ = 0.516, p = 0.002, respectively) and had a negligible or weak correlation with body mass index (BMI), BMI standard deviation score (SDS), waist circumference (WC), fasting insulin, homeostatic model assessment of insulin resistance (HOMA-IR), serum triglyceride, low-density lipoprotein (LDL), high-density lipoprotein (HDL) and total cholesterol levels. The sensitivity and specificity of USG in the diagnosis of NAFLD were 81% (95% confidence interval 54%–95%) and 50% (27%–73%), respectively. The MR fat fraction had a moderate positive correlation with ultrasound grades of fatty liver (ρ = 0.487, p = 0.003).

Conclusions

Serum ALT and AST are potential biochemical markers to assess the degree of hepatic steatosis in NAFLD, which needs validation in further studies. USG can be used as a screening tool for NAFLD, but the diagnosis should be confirmed by estimating the MR fat fraction.
The number of negative lymph nodes is positively associated with survival in esophageal squamous cell carcinoma patients in China
Authors: Yu Lan , Zhang Xiao-Tao , Guan Shang-Hui , Cheng Yu-Feng , Li Lin-Xi
Published: March 2020

Background

There is a controversial relationship between the negative lymph nodes (NLNs) and survival in patients with esophageal squamous cell carcinoma (ESCC). This study investigates the implications of total number of NLNs on thoracic ESCC patient prognosis.

Methods

579 thoracic ESCC patients were categorized into four groups (0-9, 10-14, 15-19 and ≥20 NLNs). Univariate analysis was done by the log-rank tests while multivariate analysis was undertaken using Cox regression models. Survival analysis was determined employing the Kaplan-Meier method.

Results

When the numbers of NLNs were 9 or less, 10 to 14, 15 to 19 and 20 or more, patients of 3-year survival rates were 21.7%, 40.0%, 61.2% and 77.5%, respectively (P<0.001). In the node-negative and node-positive subgroups, 3-year survival rates were 34.9% and 14.3%, 50.9% and 19.3%, 65.6% and 51.8%, 81.4% and 68.9% respectively (P<0.001). Gender, tumor length, tumor differentiation, T and N stage as well as the total NLNs were found to be significantly linked to survival rates. Multivariate analysis showed tumor length, T stage, N stage and total NLNs were independent prognostic factors for ESCC patients.

Conclusion

NLNs numbers is a significant independent prognostic indicator for thoracic ESCC patients’ survival after curative esophagectomy.
RAF1 expression is correlated with HAF, a parameter of liver computed tomographic perfusion, and may predict the early therapeutic response to sorafenib in advanced hepatocellular carcinoma patients
Authors: Tian Ninzi , Wu Dong , Tang Ming , Sun Huichuan , Ji Yuan , Huang Cheng , Chen Lingli , Chen Gang , Zeng Mengsu
Published: March 2020

Objectives

Monitoring the early treatment effect of sorafenib in advanced hepatocellular carcinoma (HCC) patients is a diagnostic challenge. In a previous study, we reported the potential role of liver computed tomography perfusion (CTP) in the assessment of the response to sorafenib therapy in HCC. The present study aims to investigate whether sorafenib-targeted genes is correlated with CTP parameter, and investigate the potential of sorafenib-targeted genes in early prediction of therapeutic response to sorafenib in advanced HCC.

Methods

A total of 21 HCC patients were enrolled. Sorafenib was administered orally at a dose of 400 mg twice daily continuously. Treatment response was assessed using modified response evaluation criteria in solid tumors (mRECIST) criteria. CTP scanning was performed before and after two weeks of sorafenib treatment using a 320-detector row CT scanner. The perfusion parameters of portal vein flow (PVF), hepatic artery flow (HAF), and perfusion index (PI) were acquired by CTP. The expression levels of several sorafenib-targeted genes were assayed using real-time quantitative PCR and western blot analysis. Logistic regression was performed to analyze the relationship between HAF values and RAF1 expression levels.

Results

According to mRECIST, the disease control rate (CR+PR+SD) of treatment group was 70.5% after two months of treatment. Compared to background controls, tumor tissues exhibited higher HAF. A sorafenib-targeted gene, RAF1 expression, was increased in tumor tissues especially in the sorafenib-resistant group. The sorafenib-resistant group exhibited a significantly higher RAF1 expression and HAF than the sensitive group. Moreover, the RAF1 expression is positively correlated with the HAF value.

Conclusion

RAF1 expression might predict therapeutic effects of sorafenib in advanced HCC, where RAF1 could potentially serve as a molecular marker for monitoring early therapeutic effects after sorafenib treatment.
Differentiation of pontine infarction by size
Authors: Yang Lei , Qin Wei , Li Yue , Yang Shuna , Gu Hua , Hu Wenli
Published: March 2020

Purpose

We hypothesized that the current criteria may be unsuitable for lacunar pontine infarctions (LPI) diagnosis and that size criteria may indicate different stroke mechanisms.

Methods

A total of 102 patients with isolated pontine infarctions were divided into a parent artery disease (PAD) and non-PAD groups according to stenosis of basilar artery. Further, 86 patients from the non-PAD group were divided into paramedian pontine infarction (PPI) and LPI groups. Data were collected from the three groups. The “golden” criterion for LPI was established based on the location of the infarction. A receiver operating characteristic (ROC) curve were used to evaluate the optimal cutoff value to use as an LPI diagnostic indicator.

Results

There was a high prevalence of patients with PAD in both asymptomatic carotid atherosclerosis (ACAS) and PPI groups. Patients with PPI had a higher prevalence in diabetes and ACAS than those with LPI. Based upon the ROC curve, the optimal lesion size cutoff value for use as an LPI diagnostic indicator was 11.8 mm.

Conclusions

Diffusion weighted imaging (DWI) cutoff points for predicting LPI may differ from that of the middle cerebral artery territory. The diameter of LPI may also indicate different stroke mechanisms.
LncRNA ZEB1-AS1 regulates colorectal cancer cells by miR-205/YAP1 axis
Authors: Jin Zhong , Chen Bing
Published: March 2020

Background

Recent studies demonstrated that long non-coding RNAs (lncRNAs) were involved in many biological processes. Dysregulated lncRNAs are related to many cancers, including colorectal cancer (CRC). However, the molecular mechanism of lncRNA ZEB1-AS1 in CRC is not clear.

Methods

LncRNA ZEB1-AS1, miR-205, and YAP1 expression were measured by quantitative reverse transcriptase PCR (QRT-PCR). YAP1 protein expression was measured by western blotting. Cell viability was measured by MTT assay. Cell apoptosis was detected by flow cytometry. Luciferase reporter assay was used to confirm the relationship between ZEB1-AS1, miR-205, and YAP1.

Results

LncRNA ZEB1-AS1 and YAP1 was upregulated in CRC tissues. The expression of YAP1 was positively correlated with ZEB1-AS1. Knockdown of ZEB1-AS1 inhibited cell viability and induced apoptosis in CRC cell line SW480 and HCT116 which could be reversed by overexpression of YAP1. ZEB1-AS1 targeted and regulated miR-205 which could directly bind to YAP1. Meanwhile, ZEB1-AS1 regulated the expression of YAP1 via modulating miR-205.

Conclusion

Long non-coding RNA ZEB1-AS1 silencing could inhibit cell proliferation and induce apoptosis of colorectal cancer via regulating miR-205 and YAP1.
Tissue coagulation in laser hemorrhoidoplasty – an experimental study
Authors: Danys Donatas , Pacevicius Julius , Makunaite Gabija , Palubeckas Rolandas , Mainelis Antanas , Markevicius Narimantas , Strupas Kestutis , Poskus Tomas
Published: March 2020

Background

Laser hemorrhoidoplasty (LHP) is a new technique for treatment of hemorrhoids. The exact extent of coagulation is not visible at the time of the procedure. There currently is no experimental or clinical data on the subject.

Objective

To evaluate the length of coagulation defect according to power and activation time of 1470nm diode laser on the perianal tissue model.

Methods

Fresh anorectal tissue of twenty-four pigs was used to produce 54 experimental samples. Each sample was randomly assigned to the laser power of 6, 8 and 10 W and 1, 2 or 3-second pulses. The procedure was performed using Biolitec Ceralas © diode laser with 1.85 mm optical fiber. The fiber was inserted in a manner, similar to intrahemorrhoidal laser application. Samples were evaluated using low-power and high-power light microscopy by a single pathologist. The length of tissue injury was measured on high-magnification microscopy.

Results

The longest tissue injury (mean 3.93 mm) was caused by the longest laser exposure time (3 sec) with no significant difference between laser power used.

Conclusions

8 W 3-second application of the 1470nm diode laser results in coagulation area approximately 4 mm, and further coagulation should be initiated approximately 5 mm from the first one.
Classification of pathological types of lung cancer from CT images by deep residual neural networks with transfer learning strategy
Authors: Wang Shudong , Dong Liyuan , Wang Xun , Wang Xingguang
Published: March 2020

Lung cancer is one of the most harmful malignant tumors to human health. The accurate judgment of the pathological type of lung cancer is vital for treatment. Traditionally, the pathological type of lung cancer requires a histopathological examination to determine, which is invasive and time consuming. In this work, a novel residual neural network is proposed to identify the pathological type of lung cancer via CT images. Due to the low amount of CT images in practice, we explored a medical-to-medical transfer learning strategy. Specifically, a residual neural network is pre-trained on public medical images dataset luna16, and then fine-tuned on our intellectual property lung cancer dataset collected in Shandong Provincial Hospital. Data experiments show that our method achieves 85.71% accuracy in identifying pathological types of lung cancer from CT images and outperforming other models trained with 2054 labels. Our method performs better than AlexNet, VGG16 and DenseNet, which provides an efficient, non-invasive detection tool for pathological diagnosis.
Broadband nonlinear optical response in GeSe nanoplates and its applications in all-optical diode
Authors: Tang Jie , Zhang Feng , Zhou Feng , Tang Xian , Dai Xiaoyu , Lu Shunbin
Published: March 2020

Germanium selenide nanoplates (GeSe NPs) are considered to have broadband nonlinear optical (NLO) properties and great potential for applications in nanophotonic devices. In this work, we systematically studied the NLO response of GeSe NPs by the open-aperture Z-scan technique. GeSe NPs exhibit strong saturable absorption at wavelengths of 400, 800, and 1064 nm with different pulse durations. Furthermore, we investigated the excited carrier dynamics of GeSe NPs by the non-degenerate pump-probe technique. The fast and slow relaxation times at different wavelengths of 800, 871, 1064, and 1100 nm were components with lifetimes of about 0.54–1.08 and 52.4–167.2 ps, respectively. The significant ultrafast NLO properties of GeSe NPs imply their potential in the development of nanophotonic devices. Here, we designed and fabricated the all-optical diode by means of the GeSe/C60 tandem structure and demonstrated that the saturable absorption behavior of GeSe NPs can be used to fabricate a photonic diode, which exhibits nonreciprocal transmission of light similar to that of an electron diode.
Recent progress of pulsed fiber lasers based on transition-metal dichalcogenides and black phosphorus saturable absorbers
Authors: Liu Xing , Gao Qun , Zheng Yang , Mao Dong , Zhao Jianlin
Published: March 2020

Transition-metal dichalcogenides (TMDCs) and black phosphorus (BP) are typical 2D materials with layer-dependent bandgaps, which are emerging as promising saturable absorption materials for pulsed fiber lasers. In this review, we discuss the nonlinear saturable absorption properties of TMDCs and BP, and summarize the recent progress of saturable absorbers from fabrication methods to incorporation strategies. The performances of saturable absorbers and the properties of Q-switched/mode-locked fiber lasers at different wavelengths are summarized and compared to give a comprehensive insight to optical modulators based on TMDCs/BP, and to promote their practical applications in nonlinear optics.
Crystal structure of (E)-4-hydroxy-3-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)pent-3-en-2-one, C13H12N2O3S
Authors: Zou Juan , Zhao Chen-Liang , Zhang Qi-Long , Pan Lu-Tai , He Kang
Published: March 2020

C13H12N2O3S, monoclinic, P21/c (no. 14), a = 12.3541(8) Å, b = 14.3818(10) Å, c = 7.3757(5) Å, β = 96.471(2)°, V = 1302.12(15) Å3, Z = 4, R
gt(F) = 0.0417, wR
ref(F
2) = 0.1080, T = 293(2) K.
The crystal structure of (E)-2-((2-hydroxy-4-ethoxybenzylidene)amino)-2-methylpropane-1,3-diol monohydrate, C13H21NO5
Authors: Liguo Yang , Zhen Zhang , Yongsheng Niu , Fang Wang , Dayong Tian
Published: March 2020

C13H21NO5, orthorhombic, Pca21 (no. 29), a = 19.718(8) Å, b = 9.102(4) Å, c = 8.091(4) Å, V = 1452.1(11) Å3, Z = 4, R
gt(F) = 0.0452, wR
ref(F
2) = 0.1289, T = 298 K [1–3].
A Syntactic Approach to Meillassoux’s Concept of Hyper-Chaos
Authors: Orensanz Martin
Published: March 2020

Axiomatic systems can be understood as subsets of syntactic systems. By a process of increasing abstraction, the notion of a syntactic system can become useful for understanding Meillassoux’s concept of hyper-Chaos.
Towards a green and sustainable fruit waste valorisation model in Brazil: optimisation of homogenizer-assisted extraction of bioactive compounds from mango waste using a response surface methodology
Authors: Zuin Vânia G. , Segatto Mateus L. , Zanotti Karine
Published: March 2020

Food waste valorisation is currently at the core of discussions and development of future economic models which, allied to the application of green and sustainable technologies, offers a viable alternative to shift industrial practices towards a circular bioeconomy. The feasibility and technological possibilities based on an integrated mango waste biorefinery concept, focusing on the extraction of bioactive compounds, are discussed in this paper. Additionally, a statistically robust methodology is presented as a green approach to optimise the variables of a sustainable, low time and energy consumption extraction technique (homogenizer-assisted extraction). Maximum concentrations of the bioactive compounds were obtained in similar values of parameters ethanol/water concentration (67.73 and 70.11 %), sample/solvent ratio (29.33 and 28.17 %) and time (4.47 and 5.00 min) for mangiferin (354.4 mg/kg DW) and hyperoside (258.7 mg/kg DW), respectively. These results demonstrated the efficiency of the proposed green and sustainable method to obtain bioactive compounds from a very common and significant tropical fruit waste in Brazil, based on an integrated mango biorefinery concept.
A combination of experimental and computational methods to study the reactions during a Lignin-First approach
Authors: Kumaniaev Ivan , Subbotina Elena , Galkin Maxim V. , Srifa Pemikar , Monti Susanna , Mongkolpichayarak Isara , Tungasmita Duangamol Nuntasri , Samec Joseph S. M.
Published: March 2020

Current pulping technologies only valorize the cellulosic fiber giving total yields from biomass below 50 %. Catalytic fractionation enables valorization of both cellulose, lignin, and, optionally, also the hemicellulose. The process consists of two operations occurring in one pot: (1) solvolysis to separate lignin and hemicellulose from cellulose, and (2) transition metal catalyzed reactions to depolymerize lignin and to stabilized monophenolic products. In this article, new insights into the roles of the solvolysis step as well as the operation of the transition metal catalyst are given. By separating the solvolysis and transition metal catalyzed hydrogen transfer reactions in space and time by applying a flow-through set-up, we have been able to study the solvolysis and transition metal catalyzed reactions separately. Interestingly, the solvolysis generates a high amount of monophenolic compounds by pealing off the end groups from the lignin polymer and the main role of the transition metal catalyst is to stabilize these monomers by transfer hydrogenation/hydrogenolysis reactions. The experimental data from the transition metal catalyzed transfer hydrogenation/hydrogenolysis reactions was supported by molecular dynamics simulations using ReaXFF.
A narrative approach to human-robot interaction prototyping for companion robots
Authors: Koay Kheng Lee , Syrdal Dag Sverre , Dautenhahn Kerstin , Walters Michael L.
Published: March 2020

This paper presents a proof of concept prototype study for domestic home robot companions, using a narrative-based methodology based on the principles of immersive engagement and fictional enquiry, creating scenarios which are inter-connected through a coherent narrative arc, to encourage participant immersion within a realistic setting. The aim was to ground human interactions with this technology in a coherent, meaningful experience. Nine participants interacted with a robotic agent in a smart home environment twice a week over a month, with each interaction framed within a greater narrative arc. Participant responses, both to the scenarios and the robotic agents used within them are discussed, suggesting that the prototyping methodology was successful in conveying a meaningful interaction experience.
Simultaneous separation of Am and Cm from Nd and Sm by multi-step extraction using the TODGA-DTPA-BA-HNO3 system
Authors: Sasaki Yuji , Morita Keisuke , Matsumiya Masahiko , Nakase Masahiko
Published: March 2020

The simultaneous separation of Am and Cm from lanthanides is important for atomic energy fields. However, the process is difficult owing to the chemical behavior of trivalent metal ions with similar ionic radii. All lanthanides, Am, and Cm can be extracted by diglycolamide (DGA). In addition, relatively high separation factors between An and Ln were obtained by the extraction system of TODGA, DTPA (diethylenetriamine-N,N,N′,N″,N″-pentaacetic acid) and HNO3. In this work, DTPA-BA (diethylenetriamine-N,N′,N″-triacetic-N,N″-bisamide), which is an improved version of DTPA, was employed for the separation of Ln and An. After performing a basic study on DTPA-BA, a relatively high separation factor (approximately 8) for actinides/lanthanides was obtained. Then, the multi-step extraction was performed. Thus, the recoveries of 94.7 % for Nd and 4.7 % for Am and Cm in organic phase, and 5.3 % Nd and 95.3 % for Am and Cm in aqueous phase were obtained.
The use of nanotechnology to prevent and mitigate fine migration: a comprehensive review
Authors: Madadizadeh Ali , Sadeghein Alireza , Riahi Siavash
Published: March 2020

Fine migration is a serious problem in petroleum reservoir that causes damage to the reservoir and production equipment. One of the methods to solve this problem is using nanotechnology. Nanoparticles can reduce fine migration by various mechanisms such as reducing the zeta potential, changing the total interaction energy between surfaces, pH, and roughness of the particle’s surfaces. This study presents a review of the methods such as sand pack test, core flood test, and proppant test that study the nanoparticles’ influence on fine migration. Also, there are two different scenarios for the use of nanoparticles to mitigate fine migration. One of these scenarios is the co-injection of nanoparticles and particles suspended fluid, and another scenario is the initial injection of nanoparticles into the porous media (pre-flush). The results of the studies have shown that pre-flush of nanoparticles has a better effect on the control of fine migration.
Thermodynamic models applied to CO2absorption modelling
Authors: N. Borhani Tohid , Nabavi Seyed A. , Hanak Dawid P. , Manovic Vasilije
Published: March 2020

Carbon capture, utilisation, and storage (CCUS) is considered as the least cost-intensive option towards achieving the emission reduction target by 2050. One of the important technologies to remove CO2from different gas streams is solvent-based CO2capture. Modelling and simulation of solvent-based CO2capture processes have been attracting a lot of attention in recent years. Thermodynamic models play a vital role in these modelling and simulation studies. Hence, this study critically reviews the thermodynamic models applied in the modelling of solvent-based CO2capture systems over the past years, to provide a guideline for the selection of the optimum models for future studies. These models have wide applications in two main areas: equilibrium modelling [vapour-liquid equilibrium (VLE) (physical) and speciation equilibrium (chemical)], and calculation of some thermodynamic properties. VLE and speciation modelling methods are classified rigorously. VLE modelling methods are classified as homogeneous, heterogeneous, and empirical, and speciation modelling methods are classified as iterative (which could be stoichiometric and non-stoichiometric) and non-iterative. Thermodynamic models are categorised into three key families: activity-coefficient based, equation of state based, and quantum mechanical based. Theory and concepts of different thermodynamic models are presented. Some selected studies that used each family of thermodynamic models are reviewed.
Vietnam: country report on children’s environmental health
Authors: Thai Ha Le
Published: March 2020

As a developing country, Vietnam is facing many problems such as environmental pollution caused by industrialization, urbanization and the ethnic minority gap. Besides, Vietnam is one of the 10 countries most vulnerable to the effects of climate change and natural disasters. Vietnam has more than 26.3 million children under 16 years of age, with the ratio being 114 boys/100 girls. Children are especially vulnerable to environmental risks. This review includes much data collected during 2010–2018 on children’s environmental health in Vietnam.
Doing Age zwischen Selbstoptimierung und Selbstermächtigung durch die Arbeit am Körper im Fitnessstudio
Authors: Sobiech Gabriele , Hartung Sebastian
Published: March 2020

Der demografische Wandel stellt Staat und Politik vor neue, vor allem finanzielle Herausforderungen. Im Zuge einer Rekonfiguration des Ruhestands wird im neoliberalen Sinn die Übernahme von Verantwortung für finanzielle, soziale und körperliche Risiken des Alter(n)s vom Staat zu den Individuen hin verschoben. Alter(n) (doing age) ist als soziales Konstrukt aufzufassen, das durch die ihm innewohnenden machtgeladenen Zuschreibungen und Symboliken, Selbstermächtigungschancen bereithält, vor allem dann, wenn dem Trend zur Altersaktivierung gefolgt wird. Die im Rahmen einer qualitativen Interviewstudie erhobenen Selbsttechniken (Foucault) der im Fitnessstudio aktiven, älteren Frauen zeigen, dass damit einerseits die eigene, soziale Positionierung gestärkt wird, andererseits kann mit der Abwertung anderer, die dem Trend nicht folgen, eine neue Form des ‚Lookism‘ entstehen.
On Canons as Music and Muse
Authors: Grasso Julianne
Published: March 2020

Canons—of music, video games, or people—can provide a shared pool of resources for scholars, practitioners, and fans; but the formation of canons can also lead to an obscuring or devaluing of materials and people outside of a canon. The four authors in this colloquy interrogate issues of canons relating to video game music and sound from a variety of perspectives. Each author considers an aspect of canonization and argues for a wider purview. In “Rewritable Memory: Concerts, Canons, and Game Music History,” William Gibbons examines the ways in which concerts of video game music may create canons and reinforce particular historical narratives. In “On Canons as Music and Muse,” Julianne Grasso views the music originally presented in a video game as itself a type of canon and argues that official and fan arrangements of original game music may provide windows into lived experiences of play. In “The Difficult, Uncomfortable, and Imperative Conversations Needed in Game Music and Sound Studies,” Hyeonjin Park highlights issues of diversity and representation in the field of video game music and sound studies, with respect to the people and music that make up the subjects of the field, the people who produce scholarship in the field, and the people who engage with game music and sound. In “Canon Anxiety?” Karen Cook pulls together various issues of academic canons to question the scope, focus, and diversity of the growing field in which the Journal of Sound and Music in Games exists.
Lokálisan és lokoregionálisan előrehaladott, magas kockázatú endometriumtumorok műtét előtti szisztémás előkezelése
Authors: Kalincsák Judit , Gőcze Péter , Bohonyi Noémi , Bárdos Nikoletta , Koppán Miklós , Kovács Krisztina , Toller Gábor Lénárd , Csima Melinda , Papp Szilárd
Published: March 2020

Absztrakt:

Bevezetés: A méhtestrák a fejlett országokban a leggyakoribb
invazív nőgyógyászati daganat. A legjobb túlélési eredmények a tumor műtéti
eltávolítása után várhatók, ezért a komplex ellátás célja a lokálisan és
lokoregionálisan előrehaladott betegség reszekábilissé tétele.
Célkitűzés: A jelen közleményben azt vizsgáljuk, hogy a
neoadjuváns kemoterápiával kezelt és műtéten átesett betegek teljes túlélése
jobb-e a csak sugárkezelést kapott páciensekéhez képest.
Módszer: 2015. január és 2018. december között 28,
lokálisan, illetve lokoregionálisan előrehaladott, primeren irreszekábilis,
magas kockázatú méhtesttumoros betegnél végeztünk neoadjuváns szisztémás
kezelést paklitaxel-karboplatin alkalmazásával. Ezt követően radikális
hysterectomia, kétoldali petefészek-eltávolítás történt lymphadenectomiával.
Eredmények: A 6 ciklus kemoterápia után készült
kontroll-MR-vizsgálat minden esetben méretbeli csökkenést igazolt. Minden
betegnél véghez vihető volt a teljes tumoreltávolítás. A szövettani leletek
alapján 4 páciens esetében igazolódott maradék tumor az eltávolított
nyirokcsomókban. A 2 éves túlélési arány 65,5%, a 2 éves progressziómentesség
66,1% volt. A medián teljes túlélés 16,5 hónap volt. Mindegyik érték jobbnak
bizonyult a csak sugárkezelést kapó csoportnál. Következtetés:
A neoadjuváns kezelés hatékony módja lehet a reszekabilitás feltételeinek
megteremtésében, ami túlélésbeli előnnyel járhat. A komplex ellátás ellenére a
betegek túlélése továbbra is szerény. Orv Hetil. 2020; 161(11): 425–433.
Postdissectiós aortaaneurysma endovascularis kezelése „candy-plug” technikával perzisztáló állumen esetén
Authors: Hidi László , Csobay-Novák Csaba , Juhász Viktória , Suhai Ferenc , Szeberin Zoltán , Sótonyi Péter
Published: March 2020

Absztrakt:

Teljes aortára kiterjedő, A-típusú dissectio miatt Bentall-műtéten, mellkasi
aortoaorticus interpositum implantáción és mellkasi sztentgraftbeültetésen
átesett 79 éves férfi betegnél perzisztáló állumen miatt kialakult, krónikus, 60
mm-es, thoracoabdominalis postdissectiós aortaaneurysma megoldásaként, hazánkban
először, az ún. „candy-plug” technikát alkalmaztuk. Az aortadissectio proximalis
berepedésének lefedésével az endovascularis mellkasi aortarekonstrukció (TEVAR)
elősegíti az állumen thrombosisát és az aorta remodellálódását, a thrombosis
azonban gyakran – az esetek kb. 60%-ában – csak részleges, és az állumen
keringése a TEVAR mellett is fennmaradhat. Ezekben az esetekben az aorta további
jelentős tágulásával kell számolnunk, amely gyakran csak nagy kockázatú nyitott
műtéti vagy endovascularis beavatkozásokkal kezelhető. Ezeknek az eseteknek a
biztonságosabb megoldása érdekében fejlesztették ki a standard TEVAR és az
állumen zárását szolgáló módszerek kombinációját. Ilyen új eljárás az esetünkben
is alkalmazott „candy-plug” technika, amely minimálinvazív úton megszüntetve az
állumen keringését és megállítva ezzel az aneurysma progresszióját, hatékony és
biztonságos megoldást jelenthet az aortadissectiók késői szövődményeként
megjelenő postdissectiós aortaaneurysmák ellátásában. Orv Hetil. 2020; 161(11):
437–439.
Az e-cigarettázással összefüggésbe hozható tüdőbetegség
Authors: Xantus Gábor , Kanizsai Péter
Published: March 2020

Absztrakt:

Több mint ezer olyan légúti megbetegedést tart számon a Centers for Disease
Control and Prevention (Atlanta, GA, USA), amelynek köze lehet az elektromos
cigaretta használatához. Több mint nyolcszáz esetről bizonyosodott be (közülük
18 halálos kimenetelű volt), hogy vaporizálással összefüggő tüdősérülésről
(vaping-associated lung injury – VALI) van szó. Bizonyosnak látszik az is, hogy
az e-cigarettákban (mind a nikotin-, mind a kannabiszpatronokban) használt
folyadékok több alkotóeleme potenciálisan mérgező. Még nem pontosan tisztázott
ugyan, hogy mely komponens(ek) felelősek(ek) az esethalmozódásért, de a
vizsgálatok fókuszában főleg olyan folyadékpatronok állnak, amelyek
kannabiszszármazékokat tartalmaznak, a betegek nagy része ugyanis legális vagy
illegális kannabiszolajat használt. A közegészségügyi hatóságok az e-pöfékelést
világszerte mindeddig a dohányzás biztonságos alternatívájaként jegyezték.
Azokban az országokban, ahol a kannabisz használata legális, az e-cigaretták
hallatlan népszerűségre tettek szert diszkrét használatuk okán, humán
vizsgálatok azonban még nem történtek a kannabisz-hatóanyagok e-cigarettával
történő porlasztásával kapcsolatban, ezért ennek a beviteli útnak a
biztonságossága nem ismert. Egy 2017-ben megjelent áttekintő cikk azzal a
következtetéssel zárta értekezését, hogy az e-cigaretták biztonságossága
ismeretlen ugyan, ám feltételezhető, hogy kevésbé káros, mint a
kannabisztartalmú cigaretták szívása. Magyar, amerikai, ausztrál és európai
szakmai szervezetek 2015 óta figyelmeztettek a szabályozatlan terjesztésben
rejlő veszélyekre, ugyanakkor elkötelezték magukat a jövőbeli alapos klinikai
vizsgálatok szükségessége mellett. Amennyiben a jelenlegi vizsgálatok
kimutatják, hogy az e-cigarettázás maga nem feltétlenül káros, akkor alkalmasint
új út nyílhat a kannabisz orvosi célú kutatásában és alkalmazásában, ellenkező
esetben azonban jelentős változások várhatók a dohánytermékek piacán és a
leszoktatást segítő programokban. Orv Hetil. 2020; 161(11): 413–418.
A De Quervain-féle tendinopathia kezelése konzervatív módszerekkel
Authors: Földvári-Nagy László , Takács Johanna , Hetthéssy Judit Réka , Mayer Ágnes Andrea , Szakács Noémi , Szávin-Pósa Ágnes , Lenti Katalin
Published: March 2020

Absztrakt:

Bevezetés: A De Quervain-féle tendinopathia a csukló-kéz
régióját érintő betegség. A hüvelykujj mozgatása fájdalmassá válik, a kéz
funkciója jelentősen romlik. A betegség a legújabb kutatások szerint inkább
degeneratív, semmint gyulladásos eredetű. Első lépésként a kéz sínezése,
nemszteroid gyulladáscsökkentő szerek és különböző fizikoterápiás kezelések
alkalmazása javasolt. Hatástalanságuk esetén további lehetőség az ínhüvelybe
fecskendezett szteroidinjekció és a műtéti úton végzett ínhüvelybemetszés.
Célkitűzés: Kutatásunkban megvizsgáltuk, hogy az
excentrikus tréninggel kibővített konzervatív kezelés megfelelő alternatíváját
nyújthatja-e a jelenleg elfogadott kezelési lehetőségeknek.
Módszer: Az excentrikus tréning 8 hétig tartott, melyet
indokolt esetben 12 hetesre bővítettünk. A betegek (n = 9) a betanítást követően
naponta többször végezték a tréninget, amit a heti találkozók alkalmával
kontrolláltunk. Az 1., a 8., valamint a 12. heti találkozó során az inspekciót
követően mértük az ízületi mozgástartományt, az izomerőt, a fájdalmas régiók
számát, illetve elvégeztük a ’Numeric Pain Rating Scale’, a ’Quick Disabilities
of the Arm, Shoulder and Hand’, valamint a ’Patient-Rated Wrist Evaluation’
kérdőívek felvételét. A méréseket páros mintás t-teszttel és ismételt méréses
varianciaanalízissel elemeztük. Az elemzéseket IBM SPSS Statistics 25.0 és
Microsoft Office Excel Professional Plus 2016 programmal végeztük; p<0,05
esetén tekintettük statisztikailag szignifikánsnak eredményeinket.
Eredmények: Szignifikáns javulást mértünk a fájdalom
intenzitása (’Numeric Pain Rating Scale’ p = 0,005, n = 9) és a kéz, valamint a
csukló funkciója terén (’Quick Disabilities of the Arm, Shoulder and Hand
Outcome Measure’ kérdőív 1. rész p<0,001, 2. rész p<0,001, ’Patient-Rated
Wrist Evaluation’ kérdőív p<0,001; n = 9). Következtetés:
Eredményeink alapján megfelelő betegbeválasztás mellett az excentrikus
tréninggel kibővített konzervatív kezelés valós alternatívája lehet a jelenleg
alkalmazott kezeléseknek. Orv Hetil. 2020; 161(11): 419–424.
A cirkuláris ribonukleinsav és tumorbiológiai jelentősége
Authors: Turai Péter , Igaz Péter
Published: March 2020

Absztrakt:

Az utóbbi évek molekuláris biológiai kutatásainak egyik legjelentősebb fejezete a
nem kódoló ribonukleinsavak (RNS-ek) kutatása. A nem kódoló RNS-ek csoportján
belül külön csoportot képeznek a cirkuláris RNS-ek, amelyek jelentőségét
mostanában kezdjük megismerni. E rendkívül stabil molekulák többféle
mechanizmuson keresztül – például a szintén nem kódoló RNS-ek családjába tartozó
mikro-RNS-ek megkötése vagy a transzláció befolyásolása révén – vesznek részt a
génexpresszió szabályozásában. A cirkuláris RNS-ek kifejeződésének megváltozását
több daganatban leírták, ami stabilitásuk révén biomarkerként történő
alkalmazásukat vetíti előre, illetve molekuláris célpontként is szóba jöhetnek.
Összefoglaló cikkünkben a cirkuláris RNS-ek általános jellemzőit és
tumorbiológiai jelentőségét mutatjuk be. Orv Hetil. 2020; 161(11): 403–412.
EKG-gyöngyszem: acut coronaria szindrómát utánzó sinuscsomó-betegség – az aVR-jel
Authors: Tomcsányi János
Published: March 2020

Absztrakt:

Az aVR-jel főtörzs-, illetve súlyos háromér-betegségnek lehet az EKG-jele, de nem
egyenlő a STEMI-vel, és nem szenzitív jele a coronariabetegségnek. Erre mutat
példát a következő eset. Egy 89 éves nőbeteget mellkasi fájdalommal,
pitvarfibrillációval és sok elvezetésre kiterjedő ST-depresszióval vettünk fel.
Az aVR-elvezetésben azonban ST-eleváció volt. Az aVR-jelre való tekintettel
urgens coronarographia történt, negatív eredménnyel. Később a sinusrhythmus
helyreállt. A repolarizációs zavarok megszűntek a sinusrhythmus alatt. A
monitorelvezetések váratlan hosszabb pauzákat mutattak, ami az EKG alapján
változó SA-blokknak felelt meg. Mindezek alapján sinuscsomó-betegség állt a
háttérben, amelyben a pitvarfibrilláció alatti repolarizációs zavar acut
coronaria syndromát mimikázott. A beteg pacemakerbeültetés után orális
antikoaguláns kezeléssel távozott otthonába. Orv Hetil. 2020; 161(11):
434–436.
Penangkapan Udang Penaeid Pasca Moratorium dan Pelarangan Kapal Trawl di Kabupaten Kaimana Propinsi Papau Barat
Authors: Sururi Misbah , Razak Abudarda , Simau Silvester , Gunaisah Endang , Ulat M Ali , Sudirman Sudirman , Handayani Handayani , Suruwaky, Amir , Sumbung Sepri , Suryono Muh , Mustasim Mustasim , Muhfizar Muhfizar , Muhamad Samsul
Published: March 2020

Penelitian ini mendiskripsikan penangkapan udang penaeid di Kabupaten Kaimana setelah moratorium dan Pelarangan Penangkapan ikan dengan Pukat Hela/Pukat Tarik untuk memberi gambaran dalam perencanaan pengelolaan perikanan udang yang berkelanjutan.  Metode yang digunakan dalam pengumpulan data penelitian adalah metode survei lapangan dengan mengikuti langsung kegiatan operasi penangkapan oleh nelayan, pengukuran alat tangkap dan wawancara yang dilakukan mulai bulan September – November 2017 kemudian diolah dan di bahas secara deskriptif.  Penangkapan udang penaeid di Kabupaten Kaimana setelah moratorium dan Pelarangan Penangkapan ikan dengan Pukat Hela/Pukat Tarik dilakukan oleh nelayan skala kecil yang berasal dari daerah Arguni dan Nelayan Kaimana  menggunakan trammel net dan jaring udang monofilament dengan menggunakan perahu katinting dan longboat motor tempel. Penangkapan udang dengan jaring udang PA monofilament dilakukan pada perairan pesisir pantai pada kedalamanan 1 – 5 meter dan penangkapan udang dengan trammel net dilakukan pada perairan pesisir pantai pada kedalamanan 5 – 20 m. Umumnya dasar perairan lumpur berpasir dengan warna perairan keruh abu-abu, dan sepanjang pantai terdapat hutan mangrove dengan hasil tangkapan didominasi udang banana. Musim penangkapan  terjadi pada bulan November – April untuk Perairan Arguni, dan Juni – Oktober di Perairan Teluk Kaimana.
PENGARUH PADAT TEBAR UNTUK MENINGKATKAN PRODUKTIVITAS BUDIDAYA IKAN NILEM (Osteochilus hasseltii) DENGAN PENGGUNAAN BATU AERASI HIGH OXY
Authors: Herawati Heti , Yulianti Rini , Zahidah Zahidah , Sahidin Asep
Published: March 2020

Sistem budidaya ikan secara konvensional untuk ikan nilem yang saat ini banyak dilakukan dengan padat penebaran yang tinggi agar dapat dihasilkan produksi yang tinggi pula. Hal tersebut tentu saja akan berdampak pada ketersediaan oksigen terlarut dalam kolam budidaya yang akan mengakibatkan produksi menjadi menurun. Penggunaan batu aerasi high oxy dapat meningkatkan kadar oksigen terlarut dalam kolam budidaya ikan nilem sistem konvensional sehingga produktivitas budidaya ikan nilem akan meningkat pula dengan berkurangnya tingkat kematian ikan nilem tersebut. Penelitian ini bertujuan untuk mengetahui sejauh mana pengaruh penambahan batu aerasi high oxy untuk meningkatkan kadar oksigen terlarut yang dapat menunjang keberhasilan dan produktivitas dalam system budidaya ikan nilem secara konvensional. Penelitian dilakukan di Laboratorium Fisiologi Hewan Air FPIK Unpad dengan metode eksperimental Rancangan Acak Lengkap dengan tiga perlakuan yaitu kepadatan ikan 100 ekor, 200 ekor dan 300 ekor/m2 dan empat kali ulangan. Hasil penelitian didapatkan perlakuan 200 ekor/m2 memberikan hasil yang paling baik ditunjukan dari laju pertumbuhan bobot harian dan kelangsungan hidup tertinggi selama penelitian sebesar 2,7% dan 75,4%.
Kesesuaian Penanganan Ikan di Kapal pole and line
Authors: Rossarie Dheni , Darmanto Yudhomenggolo Sastro , Swastawati Fronthea
Published: March 2020

Ikan merupakan hasil tangkapan laut yang sangat penting, disamping sebagai sumber utama protein hewani juga merupakan obyek mata pencaharian pokok bagi nelayan. Penanganan ikan di atas kapal meliputi segala tindakan terhadap hasil tangkapan di kapal, mulai dari tindakan awal sampai dengan penyimpanan. Penurunan mutu dan tingginya kerusakan pascapanen diakibatkan oleh cara penangkapan, cara penanganan yang buruk, panjangnya rantai suplai, tidak memadainya fasilitas penanganan. Kepedulian pemerintah terhadap jaminan mutu pada produk hasil perikanan sudah cukup tinggi yaitu dengan telah ditetapkan Keputusan Menteri Kelautan dan Perikanan Nomor 52A/Kepmen-KP/2013 Tentang Persyaratan Jaminan Mutu dan Keamanan Hasil Perikanan. Penelitian ini dilakukan di dermaga PT Citra Raja Ampat Canning kota Sorong yang merupakan tempat berlabuhnya kapal pole and line.  Metode penelitian yang digunakan yaitu dengan metode deskriptif dan metode survey. Metode pengambilan sampel yaitu dengan purposive sampling. Hasil penelitian menunjukkan kesesuaian penanganan ikan cakalang di kapal pole and line dengan kebijakan manajemen mutu yang telah diatur pada KEPMEN-KP 52A/2013 dari elemen yang meliputi fasilitas, peralatan, cara penanganan di atas kapal, dan peran anak buah kapal (ABK), pada kapal 1, kapal 2 dan kapal 3 yaitu sebesar 61%, sehingga dapat disimpulkan bahwa penanganan di atas kapal pole and line kurang sesuai standar.
Karakteristik Minyak Ikan Nila (Oreochromis niloticus) Hasil Pemurnian Menggunakan Arang Aktif dan Bentonit pada Hasil Samping Limbah Fillet Ikan Nila PT. Aquafarm Nusantara Semarang
Authors: Sumartini  , Supriyanto  , Pudji Hastuti
Published: March 2020

PT. Aquafarm Nusantara adalah  industri pengolahan ikan modern berbasis fillet ikan Nila  yang rutin melakukan ekspor ke berbagai negara. Daging ikan Nila merupakan bagian utama yang dijadikan produk fillet ikan dan diekspor, sehingga masih banyak limbah yang dihasilkan seperti tulang, sisik, kulit, isi perut, dan kepala ikan. Penelitian ini bertujuan untuk mengetahui karakteristik dan kualitas minyak ikan dari hasil samping industri fillet ikan nila setelah mengalami pemurnian. The method used was an experimental laboratory using eight different treatments on pale dose (charcoal) 1%, 2%, 3%, bentonite 1%, 2%, 3%, active charcoal 2% : 1%, and bentonite:active charcoal 1%, 2%. Parameters used are moisture content, melting point, free fatty acid, peroxide and iodin value, brightness and clarity. The best result of parameter analysis was showed by combining betonit: actice charcoal (2%:1%), it showed the moisture content 0.05 ± 0,02%, iodin number 121,87±2,55, peroxide number 7,92±0,00%, FFA 0,23±0,05, brightness 55,67±0,09% (L*),-1,09±0,03 (a*), 23,36 ±0.03(b*), and clarity 82,79 ± 0.51%T.
'The History and Archaeology of Jaffa 2', edited by Aaron A. Burke, Katherine Strange Burke and Martin Peilstöcker. 2017
Authors: Erker Lauren K.
Published: March 2020

The History and Archaeology of Jaffa 2, edited by Aaron A. Burke, Katherine Strange Burke and Martin Peilstöcker. Monumenta Archaeologica 41. Cotsen Institute of Archaeology Press, 2017. 472pp., Hb $98.00, ISBN-13: 9781938770111.
Competition in Aedes aegypti larvae: the effects of distributing food inputs over time v1
Authors: Steinwascher Kurt
Published: March 2020

This protocol details the three experiments analyzed in the manuscript, "Competition in Aedes aegypti larvae: the effects of distributing food inputs over time.
Canal cholesteatoma in canal stenosis: a case report
Authors: Abdullah Asma , Wan Mansor Wan Nabila , Paul Mark , Hashim Noor Dina
Published: March 2020

Purpose :

We present a-12-year old female with canal stenosis and canal cholesteatoma. We discuss the clinical, radiological and treatment option for canal cholesteatoma in canal stenosis

Discussion :

Congenital canal atresia is a failure of the development of the external auditory canal which comprises anomalies of variable severity involving pinna, external acoustic canal, middle ear structures and rarely inner ear leading to hearing impairment. Congenital canal stenosis is considered to be a subset of congenital canal atresia. This malformation results in mild to severe conductive hearing loss. Furthermore, risk of cholesteatoma increased when it is associated with stenotic ear. Radiological evaluation in the form of HRCT scan of temporal bones should always be done in these patients during their initial presentation and surgery should be planned accordingly. Their presence should be rule out prior any corrective surgery.

Conclusion :

Although the incidence of canal cholesteatoma is rare in congenital canal stenosis, all patients presenting with canal atresia or stenosis should be evaluated thoroughly due to their potential to develop cholesteatoma as it may be challenging to treat at an advanced stage in view of morbid complications.