bluuebunny/crossref_metadata_2025 huggingface dataset:
SOSIALISASI SOFTWARE ACCURATE ACCOUNTING KEPADA SISWA SMAN 1 RANCAH CIAMIS-JAWA BARAT
Authors: Kristianto Giovanny Bangun , Istiningrum RR Farida , Yuliarti Lusi
Published: October 2022

Accounting is one of the financial procedures that should be prepared by every business that is carried out. However, accounting is also useful for learning for the academic world. The world of technology is developing, so that accounting is currently being updated with an accounting system, which will make it easier for users to compile accounting reports more precisely. In this community service, the participants are students of SMAN 1 Rancah, Ciamis, West Java. The material given is the socialization of the Accurate Accounting system. Accurate Accounting is a software that is able to help its users to compile a complete, informative and easy to use accounting financial report. So that the material provided will be easily absorbed by the participants. Constraints faced such as the lack of knowledge about basic accounting and ignorance of the Accurate Accounting software became the basis for community service to be carried out. The limited implementation time can be an important concern, because the scope of the accounting world is quite broad, starting from the basics of accounting and developing accounting as a system within the company and becoming an excellent learning medium for educational development. Keywords: financial statement, accounting, accurate, system
Literasi Ekonomi dan Keuangan Syariah bagi Santriwati di Pondok Pesantren Al Falah Puteri Banjarbaru
Authors: Anwar Mukhlis Kaspul , Ma'mun Muhammad Yulian , Malihah Lola , Taufiq Ahmad , Murliana Mera , Maharani Dewi
Published: October 2022

This community service aims to provide knowledge and skillset for the pesantren community to make well-informed and wise decisions regarding Islamic financial matters. This program was conducted at the Al Falah Islamic Boarding School for Girls (Pondok Pesantren Al Falah Puteri) in Banjarbaru. The target audience of this campaign is 12th-grade students majoring in social sciences. A total of 35 female students that were representatives from 3 different classrooms, took part in this program. Lecturers of the Islamic Banking Department, Islamic Institute of Darussalam Martapura, acted as speakers at this event. The material they deliver relates to the economy in general, a glance of Islamic economics, and introduction to Islamic financial institutions. Discussion and Q & A sessions were held as an addition to this presentation to enrich the understanding and insights of financial literacy. It was seen that the students were very excited about involving in the discussion, especially when discourse the differences between conventional economics and Islamic economics. The enthusiasm of the participants showed that they were aware of the importance of understanding Islamic economics and Islamic finance in their life.
Estrutura da população adulta e regenerante de Cynophalla flexuosa (L.) J.Presl em área de mata ciliar degradada no semiárido Paraibano.
Authors:   , Firmino Nunes Guthyerres
Published: October 2022

Objetivou-se neste trabalho analisar os parâmetros fitossociológicos dos indivíduos adultos e jovens regenerantes de Cynophalla flexuosa (L.) J.Presl em mata ciliar degradada de um sistema ribeirinho intermitente no município de Serra Branca, Cariri paraibano. A avaliação ocorreu no período de fevereiro a março de 2021 e abrangeu a área ciliar degradada do riacho Lagoa da Serra (7°30’04.32’’ S e 36°42’13.12’’ W, com 511 m de altitude) pertencente à sub-bacia do Rio Taperoá. Nesse espaço foram demarcadas para a pesquisa 50 parcelas contíguas de 10 x 20 m. Foram calculados os parâmetros absolutos de densidade (DA) e frequência (FA). Foram elaboradas classes de regeneração e construídos histogramas de frequência para a definição das classes de distribuição de altura e diâmetro. Relacionado ao levantamento de jovens regenerantes foram identificados 255 indivíduos. Os indivíduos jovens da população foram registrados em 34 parcelas representando 68% do total amostrado. A altura média registrada para os jovens regenerantes foi de 0,89 m e diâmetro médio de 1,02 cm. Considerando os parâmetros fitossociológicos de densidade absoluta e frequência absoluta por classes de tamanho da regeneração natural, os maiores valores foram encontrados na Classe 1 (0,05 - 0,50 m) com 118 ind./ha. Na distribuição percentual do número de indivíduos por classe de tamanho da regeneração natural foi observado CT1 (0,05 - 0,50 m) com o maior percentual de indivíduos (46,27%). No levantamento de adultos da população foram identificados 19 indivíduos estando estes distribuídos 11 parcelas representando 22% do total de parcelas amostrado. A altura média registrada para adultos foi de 3,30 m e diâmetro médio de 5,61 cm. A classe de altura que apresentou o maior número de indivíduos foi à classe II (2,1-3,0 m), representado por 7 indivíduos amostrados. Para as classes de diâmetro a maior quantidade de indivíduos foi identificada na classe I (3,0-6,0 cm) com 16 indivíduos amostrados representando 84,21% do total de indivíduos adultos estiveram presentes nesta classe. Portanto, os dados gerados neste trabalho sobre a estrutura de jovens regenerantes e adultos de C. flexuosa em áreas de mata ciliar degradada ofertam importantes subsídios para a definição de planos de gestão de recursos naturais em bacias hidrográficas no contexto do Semiárido brasileiro propiciando desta maneira o fortalecimento das ações voltadas para a conservação dos recursos hídricos e estando assim em aderência aos objetivos 6 e 15 dos ODS 2030.
Разработка направлений развития тарифного регулирования естественных монополий
Authors: Краснова Татьяна Александровна
Published: October 2022

В статье на основе практического опыта исследуется влияние действующего тарифного регулирования естественных монополий на политику менеджмента компаний. Представлены приемы компаний естественных монополий для манипулирования исходными данными при формировании тарифа с использованием своего преимущества в виде асимметричности исходной информации. Ключевые аспекты сгруппированы по видам, исследовано преимущество, которое компания предполагает получить при их использовании. Кроме того, обоснована необходимость аудита процесса регулирования территориальных уполномоченных органов с целью обобщить и выявить основные проблемы при ошибочно принимаемых решениях. Предложены превентивные меры для предотвращения недобросовестного поведения как хозяйствующих субъектов, так и представителей государственного органа, которому делегировано право утверждения тарифа. Разработана карта направлений по векторам совершенствования регулирования естественных монополий.
Исследование и анализ цифровых валют центральных банков (CBDC)
Authors: Ваганова Оксана Валерьевна , Сидибе Махамаду , Прядко Евгения Андреевна
Published: October 2022

Современная мировая экономика развивается в условиях цифровизации, поэтому феномен цифровых валют центральных банков приобретает все более актуально-значимую роль. Центральные банки различных стран мира стали системно работать над выпуском виртуальных национальных денег, т. к. убедились в успехе внедрения криптовалют в мировую экономику. Активизация банков в этом направлении началась примерно с 2018 года после введения централизованных цифровых валют в прогресс реализации глобальных проектов. Авторы статьи исследуют основные модели цифровых валют центральных банков, разделяют эти валюты на розничные и оптовые, приводят аргументированные выводы о возможных последствиях введения цифровых валют для экономических, финансовых и платежных систем.
New Phytologist Now - Tansley Medal winner Anna Trugman
Authors: Trugman Anna
Published: October 2022

Integrating plant physiology and community ecology across scales through trait-based models to predict drought mortality

Forests are a critical carbon sink and widespread tree mortality resulting from climate-induced drought stress has the potential to alter forests from a carbon sink to a source, causing a positive feedback on climate change. Process-based vegetation models aim to represent the current understanding of the underlying mechanisms governing plant physiological and ecological responses to climate. Yet model accuracy varies across scales, and regional-scale model predictive skill is frequently poor when compared with observations of drought-driven mortality. Anna proposes a framework that leverages differences in model predictive skill across spatial scales, mismatches between model predictions and observations, and differences in the mechanisms included and absent across models to advance the understanding of the physiological and ecological processes driving observed patterns drought-driven mortality.

Hosted by New Phytologist Editor Nate McDowell

Banner image by David Tip on Unsplash
Xác định hiệu quả phối hợp hai carbapenem in vitro trên các chủng K. Pneumoniae sinh carbapenemase
Authors: Nhung Phạm Hồng , Linh Nguyễn Mỹ
Published: October 2022

Thử nghiệm đánh giá hiệu quả phối hợp hai carbapenem bằng Etest trên 50 chủng K. pneumoniae đề kháng carbapenem ở các mức độ khác nhau được cho thấy cặp phối hợp ertapenem + meropenem có hiệu quả hiệp đồng tác dụng trên 3 chủng, cộng tác dụng trên 47 chủng còn cặp cặp phối hợp ertapenem + imipenem có hiệu quả hiệp đồng tác dụng trên 7 chủng, cộng tác dụng trên 43 chủng. Không có hiện tượng đối kháng tác dụng khi phối hợp các cặp kháng sinh khác nhau trên cả 50 chủng. Khả năng hiệp đồng tác dụng của phối hợp ertapenem + imipenem có xu hướng tăng lên khi MIC carbapenem thấp. Phối hợp hai carbapenem là một lựa chọn điều trị có thể cân nhắc cho các nhiễm trùng K. pneumoniae kháng carbapenem.
Tác dụng giảm đau của TD0015 trên thực nghiệm
Authors: Hà Nguyễn Thị Thanh , Trang Trần Quỳnh , Vân Anh Phạm Thị , Liên Nguyễn Thị Hương
Published: October 2022

TD0015 là chế phẩm gồm nhiều dược liệu đã được biết có tác dụng giảm đau và chống viêm, nhằm mục đích điều trị giảm triệu chứng trong bệnh lý thoái hóa khớp. Nghiên cứu được thực hiện trên chuột nhắt trắng chủng Swiss nhằm đánh giá tác dụng giảm đau của TD0015 với ba mô hình tương ứng ba tác nhân gây đau khác nhau (nhiệt độ, cơ học, hóa học). Các thuốc đối chứng trong nghiên cứu gồm có: Aspirin đường uống liều 150 mg/kg, codein phosphat đường uống liều 20 mg/kg. Chế phẩm nghiên cứu TD0015 được sử dụng đường uống với liều 2,4 g/kg và 7,2 g/kg. Kết thúc nghiên cứu, TD0015 liều 2,4 g/kg và 7,2 g/kg có tác dụng giảm đau với tác nhân hóa học trên mô hình gây đau bằng acid acetic, với tác nhân cơ học trên máy đo ngưỡng đau, không có tác dụng giảm đau với tác nhân nhiệt độ khi nghiên cứu trên mô hình mâm nóng (hot plate). TD0015 có tác dụng giảm đau cả trung ương và ngoại biên.
Định danh đến cấp độ loài một số chủng Mycobacteria bằng phương pháp giải trình tự gen
Authors: Hà Nguyễn Thị , Hưng Nguyễn Văn , Châu Trần Minh , Nhung Phạm Hồng
Published: October 2022

Mặc dù có liên quan rất gần gũi về mặt di truyền, các loài trong chi Mycobacterium lại có sự khác biệt rất lớn về hình thái, tính chất, sự phân bố và khả năng gây bệnh cho người. Thử nghiệm sắc ký miễn dịch định danh vi khuẩn lao (TBc ID của hãng Becton Dickinson, Sparks, MD) không phát hiện được một số chủng Mycobacterium tuberculosis complex (MTBC) và không phân biệt được đến loài các chủng non-tuberculous mycobacteria (NTM). Phương pháp phân tích trình tự các đoạn gen đích (16S rRNA, gyrB, rpoB, hsp65 và ITS) trên các chủng mycobacteria có thử nghiệm TBc ID âm tính không những khắc phục được các nhược điểm nêu trên mà còn cho phép định danh đến loài cả các chủng NTM không phổ biến. Trong số 105 chủng có TBc ID âm tính thì quan sát được 56 chủng (53,3%) là MTBC và 49 chủng (46,7%) là NTM. Trong số 56 chủng MTBC, chiếm đa số là loài M. tuberculosis, chỉ có 1 chủng thuộc về loài M. bovis. Trong số 49 chủng NTM, chiếm đa số là phức hợp M. abscessus/ M. chelonae tiếp đến là phức hợp M. avium và 13 loài NTM khác chiếm tỉ lệ nhỏ.
Báo cáo ca lâm sàng: Viêm da hình roi do Bleomycin trên bệnh nhân U lympho Hodgkin
Authors: Hường Nguyễn Thị Thu , Nga Đỗ Huyền , Linh Lê Khánh
Published: October 2022

Bleomycin là một lại kháng sinh chống ung thư có nguồn gốc Streptomyces Verticillus. Độc tính trên da của Bleomycin không thường gặp như độc tính trên phổi. Viêm da hình roi là một độc tính hiếm gặp nhưng đặc trưng, với tỉ lệ xuất hiện khoảng 8 - 22%. Sau đây, chúng tôi xin báo cáo một trường hợp viêm da hình roi do Bleomycin. Bệnh nhân nữ, 20 tuổi, vào viện vì hạch cổ to kèm sốt thất thường, gầy sút cân. Bệnh nhân được chẩn đoán: U lympho Hodgkin giai đoạn IVBS (gan, lách, xương, hạch ổ bụng) và bệnh nhân được điều trị phác đồ AVBD. Sau 2 chu kỳ, bệnh nhân phàn nàn về các tổn thương tăng sắc tố da ở vùng lưng và đùi. Một chẩn đoán viêm da hình roi do Bleomycin được thiết lập và bệnh nhân được điều trị tiếp phác đồ không có bleomycin. Viêm da hình roi do Bleomycin là một tác dụng phụ hiếm gặp. Phát hiện sớm các tác dụng phụ trên da của Bleomycin giúp các bác sĩ lâm sàng có chiến lược điều trị thích hợp cho bệnh nhân.
Tác dụng chống xơ gan của viên nang cứng Silymax Complex trên mô hình gây xơ gan bằng carbon tetrachloride trên chuột nhắt trắng
Authors: Thanh Mai Phương , Vân Anh Phạm Thị , Hằng Đinh Thị Thu , Nguyệt Nguyễn Thị Minh , Thu Phạm Thị , Thúy Trần Thị
Published: October 2022

Nghiên cứu được tiến hành nhằm đánh giá tác dụng chống xơ gan của viên nang cứng Silymax Complex ở các mức liều 1,44 viên/kg/ngày và 4,32 viên/kg/ngày trên mô hình thực nghiệm gây xơ gan bằng tiêm màng bụng dung dịch CCl4 liên tục trong 19 tuần trên chuột nhắt trắng chủng Swiss. Các chỉ số đánh giá bao gồm trọng lượng gan tương đối, hoạt độ enzym gan, nồng độ MDA và hydroxyproline trong gan, và mức độ xơ gan trên hình ảnh vi thể. Kết quả nghiên cứu cho thấy viên nang cứng Silymax Complex chưa làm thay đổi rõ rệt mức độ xơ gan trên hình ảnh vi thể, tuy nhiên đã thể hiện một số tác dụng có thể giúp hạn chế tổn thương gan do CCl4 gây ra như làm giảm hoạt độ các enzym gan, xu hướng làm giảm nồng độ Bilirubin toàn phần và làm tăng nồng độ Albumin và Cholesterol toàn phần, và xu hướng làm giảm nồng độ MDA trong dịch đồng thể gan.
Đánh giá phân suất tống máu thất phải bằng siêu âm tim 3D ở bệnh nhân tăng áp lực động mạch phổi
Authors: Hiệu Hoàng Huy , Nhơn Bùi Văn , Hiển Trần Thị , Hiếu Nguyễn Lân , Việt Nguyễn Lân , Lý Nguyễn Thị Minh
Published: October 2022

Tăng áp lực động mạch phổi (TALĐMP) là bệnh lý nặng nề, gây suy thất phải, là yếu tố chính gây tử vong. Siêu âm Doppler tim ba chiều (3D) là kĩ thuật mới được áp dụng tại Bệnh viện Đại học Y Hà Nội. Nghiên cứu được thực hiện nhằm đánh giá phân suất tống máu thất phải bằng siêu âm tim 3D và mô tả sự tương quan với một số chỉ số đánh giá chức năng tâm thu thất phải trên siêu âm tim 2D. Kết quả cho thấy phân suất tống máu thất phải trên siêu âm 3D trung bình ở bệnh nhân TALĐMP là là 40,1 ± 10,6%. Phân suất tống máu thất phải ở TALĐMP tiên phát thấp hơn so với TALĐMP thứ phát. Tỷ lệ phát hiện rối loạn chức năng tâm thu thất phải trên siêu âm cao nhất khi đánh giá bằng phân suất tống máu thất phải (3D RVEF) với 63,6%. 3D RVEF tương quan rất chặt chẽ với phân suất diện tích thất phải (p = 0,7587), tương quan chặt chẽ với chỉ số vận động vòng van 3 lá ( p = 0,6834). Kết luận: Phương pháp siêu âm Doppler tim 3D thất phải là một kĩ thuật mới, không xâm lấn, có thể thực hiện lặp lại, giúp tăng giá trị chẩn đoán chính xác chức năng tâm thu thất phải ở bệnh nhân TALĐMP.
Tình trạng dinh dưỡng của học sinh 11 - 14 tuổi tại hai quận nội thành Hà Nội năm 2020
Authors: Hường Lê Thị Thu , Ngọc Trịnh Bảo
Published: October 2022

Nghiên cứu mô tả cắt ngang được thực hiện năm 2020 nhằm đánh giá tình trạng dinh dưỡng của 2452 học sinh từ 11 - 14 tuổi tại 6 trường THCS thuộc hai quận nội thành Hà Nội. Số liệu được thu thập bằng phương pháp cân đo trực tiếp tại trường học. Kết quả cho thấy tỷ lệ suy dinh dưỡng thấp còi của học sinh là 0,9%, gầy còm là 2,7%. Tỷ lệ thừa cân là 25,2%, giảm dần theo tuổi từ 11 - 14 tuổi lần lượt là 28,4%; 27,9%; 20,9%; 17,8% (p < 0,05). Tỷ lệ thừa cân ở trẻ nam cao hơn ở trẻ nữ (28% và 22,1%) với p < 0,05. Không có sự khác biệt về tỷ lệ thừa cân giữa quận Ba Đình và quận Long Biên (26,1% và 24,3% với p > 0,05). Tỷ lệ béo phì là 13,2% cũng giảm dần theo tuổi từ 11 - 14 lần lượt là 21%; 13,1%; 7,7%; 7,3% với p < 0,05; ở trẻ nam cao hơn ở trẻ nữ (19,9% và 5,6%) với p < 0,05; Có sự khác biệt về tỷ lệ béo phì giữa 2 quận, quận Ba Đình cao hơn quận Long biên (15,7% và 10,6%) với p < 0,05. Một số yếu tố liên quan đến tình trạng thừa cân, béo phì như độ tuổi, giới tính, địa điểm (p < 0,05). Tỷ lệ thừa cân, béo phì đang tăng cao ở mức đáng báo động nên cần có những biện pháp can thiệp để cải thiện tình trạng này.
Báo cáo ca bệnh: Rối loạn nhân dạng phân ly (đa nhân cách)
Authors: Hà Lê Thị Thu , Hà Nguyễn Việt , Hạnh Vũ Thị Mỹ , Tuấn Nguyễn Văn
Published: October 2022

Rối loạn nhân dạng phân ly là rối loạn nặng nhất và hiếm gặp nhất trong số các rối loạn phân ly, thường xuất hiện ở các nước Châu Âu, Mỹ hơn khu vực Châu Á. Chúng tôi báo cáo một ca bệnh rối loạn nhân dạng phân ly, điều trị nội trú tại Viện Sức khỏe Tâm thần. Chẩn đoán được xác định qua quá trình thăm khám và theo dõi, loại trừ các yếu tố liên quan đến dùng chất và bệnh lý cơ thể, lợi ích thứ phát. Quá trình điều trị, quản lý cần sát sao với người bệnh mắc rối loạn này.
Thực trạng công việc và khả năng sẵn sàng ứng phó với dịch COVID-19 của nhân viên y tế Bệnh viện Đống Đa - Hà Nội năm 2021
Authors: Anh Nguyễn Ngọc , Lam Định Thị , Thảo Trần Thị Phương , Xuân Lê Thị Thanh , Thảo Nguyễn Thanh , Quân Phạm Thị , Nhung Tạ Thị Kim , Hương Phan Thị Mai , Doanh Nguyễn Quốc , Loan Nguyễn Thị , Quỳnh Nguyễn Thị
Published: October 2022

Nghiên cứu được thực hiện nhằm mô tả thực trạng công việc và khả năng sẵn sàng ứng phó với dịch Covid-19 của nhân viên y tế. Nghiên cứu được tiến hành trên 225 nhân viên y tế làm việc tại Bệnh viện Đống Đa, Hà Nội có tuổi nghề tối thiểu 2 năm, thời gian nghiên cứ từ tháng 5/2021 đến tháng 5/2022. Kết quả cho thấy phần lớn đối tượng phải làm thêm giờ (56%), tăng khối lượng công việc (55,1%), căng thẳng khi làm việc (56,4%), hầu hết đối tượng tham gia nghiên cứu sẵn sàng và tự tin tham gia chăm sóc và điều trị bệnh nhân Covid-19 (lần lượt là: 92,0% và 93,3%) và đa số mong muốn được hỗ trợ trang thiết bị bảo hộ cá nhân (85,3%), tài chính (84,0%) và chuyên môn (76,4%).
Changes in Mobile Broadband Infrastructure in Georgia During the COVID−19 Pandemic
Authors: Nazareno Luísa , Zegura Ellen , Yang Liu Cathy
Published: October 2022

The COVID−19 pandemic brought the digital divide to center stage. This article investigates whether the crisis disrupted mobile broadband infrastructure, taking Georgia as a case study. We hypothesize that the pandemic could have slowed down ongoing infrastructure provision initiatives, as in other segments of the economy, or spurred them by bringing renewed attention and resources to overcoming the digital divide. We find that the per capita antenna gap between rural and micropolitan areas as compared to metropolitan has drastically reduced during the pandemic. Long−Term Evolution expansion was positively associated with the presence of vulnerable populations with variation across areas.
A Cross-Sectional Study on Inter-Arm Blood Pressure Difference among Healthy Young Adults
Authors: Khan Munazza , Din Zafarud , Farooq Saba , Mobin Ahsan , Hasan Fareeha , Idrees Syed Hassan
Published: October 2022

Introduction: The inter arm difference of blood pressure is the alteration in DBP and SBP between individuals’ both arms. IAD researches have been conducted in the pregnant women, elderly and subjects with DM and cardiovascular disease, but the number of studies in healthy young adults is very limited. Aim: Therefore, this analysis intended to assess the inter-arm difference in blood pressure in healthy young adults and its relation with gender, age, family history of hypertension and BMI. Study Design: A cross-sectional study. Place and Duration: In the Physiology Department of Saidu Group of Teaching Hospital Swat and Medicine department of MTI LRH, Peshawar for duration from October 2021 to March 2022. Methods: This study was held among 150 individuals. A mercury sphygmomanometer was used for measuring blood pressure. Statistical analysis was performed by means of the chi-square, paired t and SPSS 21.0 test and the Pearson correlation test. Results: The IAD absolute mean for systolic blood pressure was 6.02 ± 4.10 mm Hg, and 3.90 ± 2.79 mm Hg for DBP. There is a substantial IAD for SBP (t = 4.701, p <0.001), but no variance DBP. The IAD in SBP was suggestively related to patient’s arterial hypertension and with their family history (χ2 = 6.50, p = 0.01) but insignificantly related to age (r = +0.140, p = 0.05). The inter-arm systolic blood pressure has no substantial variance with respect to BMI and gender. Meanwhile, no statistically substantial association between gender, age, family history of hypertension, BMI, and interarm DBP. Conclusions: There is a substantial inter-arm difference in SBP amongst healthy young adult and related with age and positive hypertension family history. Keywords: Young adults, Inter-arm difference and Blood pressure.
Comparison of Efficacy of Conventional Triple Therapy and Non Bismuth Quadruple Therapy for Helicobacter Pylori Eradication
Authors: Sohail Muhammad , Fahim Muhammad , Khan Fahim Ullah , Khan Muhammad Sajjad , Akhter Shakeel , Shahab Muhammad , Naeem Sundus
Published: October 2022

Objective: To compare the efficacy of conventional triple therapy and non bismuth quadruple therapy for helicobacter pylori eradication. Setting: Gastroenterology Department, Lady Reading Hospital Peshawar. Study Design: Randomized control trial. Duration: 6 months 15th August, 2018 to 15th February 2019. Materials and Methods: In this study a total of 111 patients were observed. Patients were put in two groups, group A triple Helicobacter pylori eradication therapy and group B non-bismuth quadruple Helicobacter pylori eradication therapy. Randomization of patients to either treatment group was done through lottery method. All patients were worked up with detailed history and clinical examination to look for any known allergy to drugs used in this study, to document any comorbidity and to exclude alarm features, baseline investigations including complete blood count, Random blood sugar, liver function tests and renal function tests. H pylori stool antigen was reported from Lady Reading Hospital laboratory at time of inclusion and four weeks after completion of therapy. The purpose and benefits of study was explained to patients and written consent for participation in study was obtained. Patients were asked on follow up about adherence to the treatment. Results: In this study mean age in Group A was 44 years with SD ± 2.77. Whereas mean age in Group B was 42 years with SD ± 3.12. In Group A 55% patients were male and 45% patients were female. Where as in Group B 58% patients were male and 42% patients were female. More over Group A (triple Helicobacter pylori eradication therapy) was effective in 75% patients. Where as Group B (non-bismuth quadruple Helicobacter pylori eradication therapy) was effective in 94% patients and was not effective in 6% patients. Conclusion: Our study concludes that non bismuth quadruple therapy is more effective than triple therapy in the treatment of Helicobacter pylori eradication. Keywords: Conventional triple therapy, Non-bismuth quadruple therapy, Helicobacter pylori eradication
Diagnostic Accuracy of Multislice CT Scan in the Detection of Cervical Lymph Node Metastasis in Head and Neck Cancers
Authors: Nasrullah Zahra , Seyal Sidra , Arsalan Muhammad , Hukamdeen Sajida , Rashid Fatima , Ibrahim Anam
Published: October 2022

Objectives: To determine the diagnostic accuracy of multislice CT scan in the detection of cervical lymph node metastasis in head and neck cancers, taking histopathology as gold standard. Study design: Descriptive, cross-sectional study. Settings: Department of Radiology, Jinnah Hospital, Lahore Study duration: 8th January 2018 to 7th July 2018 Materials & Methods: Total 95patients with squamous cell carcinoma of head and neck, 15-55 years of age of both genders were selected. All the patients with prior radiation to head and neck, already proven histopathology, CRF and claustrophobic patients were excluded. Multislice computed tomography of neck was performed on Toshiba Aquilion Multislice CT scanner before and after intravenous contrast administration. Each multislice CT scan findings were looked for malignant cervical lymph nodes. Multislice CT scan findings were compared with histopathology findings. Results: Mean age was 43.21 ± 8.16 years. Out of these 95 patients, 54 (56.84%) were males and 41 (43.16%) were females with ratio of 1.3:1.All the patients were subjected to CT of neck and found that 48 were True Positive and 04 were False Positive. Among 43, CT negative patients, 04 (False Negative) had malignant cervical nodes on histopathology whereas 39 (True Negative) had benign cervical nodes on histopathology (p=0.0001). Overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of multislice CT scan in the detection of cervical lymph node metastasis in head and neck cancers, taking histopathology as gold standard was 92.31%, 90.70%, 92.31%, 90.70% and 91.58% respectively. Conclusion: This study concluded that multislice CT scan is a highly sensitive and accurate non-invasive modality for detecting cervical lymph node metastasis in head and neck cancers. Keywords: Head and Neck Cancers, Cervical Lymph Node Metastasis, Computed Tomography.
Knowledge and Practice of Vitamin D Deficiency and Risk of Depression Among Population in Makkah City, Saudi Arabia
Authors: Dagnah Rimah , Alotaibi Ozuf , Alasmari Nada Ali , Alsulami Bayan , Alzamzami Bashaer , Alhindi Yosra
Published: October 2022

Background: Depression can be correlated with severe disability, mortality, and significant healthcare costs. It is the third leading cause of disability in worldwide affecting around 840 million people1. Vitamin D, which is a distinctive hormone with target receptors found in many areas in the body and in human brain, plays an important role in the development of depression through many physiological processes. In Saudi Arabia we found that the prevalence of depression is high, however, the exact cause is unknown. Moreover, there are many risk factors that can trigger the onset of depression such as chronic infection diseases, low socio-economic statue, stressful life events, family history, traumatic experience, all these associated with risk of depression. Objective: The aim of the study was to identify and to assess the knowledge and practice of vitamin D deficiency and risk of depression among the adult population in Makkah city. Methods: This is a cross-sectional descriptive study that was done in Makkah holey city, in the western region of Saudi Arabia. Results and conclusions: The majority of this study's participants were familiar with vitamin D, with the media serving as the most prevalent source of this information. Our participants also had substantial experience with vitamin deficiency. Similarly to a study conducted in Riyadh, our findings showed that medical experts were the most often cited information source. Overall, we found that the group we examined had a strong grasp of the relationship between vitamin D insufficiency and the recognition of depressive symptoms and put that understanding into practise. Additional research into the correlation between vitamin D and depression is warranted. Keywords: Vitamin D, Depression, Knowledge, Practice, Makkah
Early Lateral Internal Sphincterotomy Versus Conservative Treatment; Our Experience in Treatment of Chronic Anal Fissure in Qazi Hussain Ahmed Medical Complex Nowshera Pakistan
Authors: Ghani Fazal , Khan Kamran Hakeem , Ahmed Kamran , Shahzad Mudassar , Khan Shahid , Khan Waseem Yar
Published: October 2022

Background: A chronic anal fissure is a longitudinal tear in the anorectal area beneath the dentate line contributing to chronic pain and emotional stress during defecation. The present study aimed to assess early surgery versus conservative treatment for managing chronic anal fissures. Methodology: This randomized control trial was carried out on 150 chronic anal fissures patients at the Department of General Surgery, Qazi Hussain Ahmed Medical Complex, Nowshera, Pakistan from March 2020 to September 2021. Patients were divided into two groups; Group-I comprised of patients who were treated conservatively and Group II consisted of patients who underwent surgical intervention. Patients above 15 years of age and fit for surgery were enrolled. A Chi-square test was used for correlating the results using SPSS version 24. Results: Of the total patients, there were 132 (88%) male and 18 (12%) female patients. The overall mean age of Group-I and Group-II was 38.7± 6.5 years and 39.6±3.67 years. The prevalence of posterior and anterior located fissures were 136 (90.7%) and 14 (9.3%) respectively. About 86 patients underwent closed LIS, out of which 77 were male and 9 were female. The patient’s main complaints were anal pain followed by bleeding. The response rate to pain relief treatments was 79% in group-I, I, and I and 97% in group II. Conclusion: Our study found that lateral internal sphincterotomy remains the gold standard for the treatment of chronic anal fissures. To avoid recurrence and obtain the best pain relief, LIS remains the gold standard for the treatment of chronic anal fissures. Keywords: Chronic anal fissure, Conservative treatment, surgical intervention
Covid-19 Association with Mucormycosis (CAM): An Experience from Single Hospital Based Study
Authors: Salam Sana , Ahmad Miraj , Alam Shaista , Ghulam Sumiyya , Qureshi Muhammad Sheraz , Abbas Bangash Aqsa Aslam,Sudhair , Khalid Aqsa , Ullah Irfan
Published: October 2022

Objective: This study aimed to assess the outcomes experienced by patients diagnosed with mucormycosis linked with COVID-19 while they were hospitalized. Study Design: Retrospective study Place and Duration: This study was carried out at Sardar Begum Dental College from January, 2022 to June 2022. Methods: There were 215 patients of both genders had age 18-80 years were presented in this study. Included patients had confirmed coronavirus disease with symptoms of mucormycosis. Patients were provided informed written consent for detailed demographics. Clinical and laboratory outcomes among all cases were assessed. We used SPSS 22.0 to analyze all data. Results: There were majority males 165 (76.7%) and 50 (23.3%) females in this study. Mean age of the patients was 45.6±17.53 years and had mean BMI 26.13±8.17 kg/m2. We found that diabetes mellitus was the most common co morbidity in 140 (65.1%) cases, followed by hypertension in 85 (39.5%) cases. Frequency of rhino orbital mucormycosis was found in 110 (51.2%) cases, sinuses in 70 (32.6%) cases and cerebral in 35 (16.3%) cases. Majority of the cases were treated by steroid. Mean hospitalization was 16.8±7.67 days. Frequency of died patients was 28 (13.02%) because of CKD, renal dysfunction and orbital involvement. Conclusion: We concluded in this study that rhino-orbital involvement, CKD and renal dysfunction were a significantly risk factors for mortality among patients of COVID-19 with mucormycosis. Keywords: Mucormycosis, Covid-19, Mortality, Hospitalization, Steroids
Uterine Artery Doppler Indices in the Various Causes of Abnormal Uterine Bleeding Confirmed with Histopathology
Authors: Amin Saira , Bacha Raham , Farooq Syed Muhammad Yousaf , Ali Tayeba , Fatima Mehreen , Noreen Sarwat , Manzoor Iqra
Published: October 2022

Background: All disturbed pattern of bleeding which arises due to different reasons such as anovulation, pregnancy, uterine abnormalities and coagulopathies is termed as abnormal uterine bleeding (AUB). Abnormal uterine bleeding is present in many forms such as heavy bleeding, short menstrual cycle, excessive and heavy menstruation, uterine bleeding at irregular period, excessive and prolonged uterine bleeding. Abnormal uterine bleeding is mostly caused by benign findings such as endometrial hyperplasia or atrophy or benign polyps. Around 5–12% of Abnormal uterine bleeding results from Endometrial Cancer. Objective: Uterine artery Doppler indices in various causes of abnormal uterine bleeding confirmed with histopathology. Methodology: A Cross-sectional Analytical study was conducted at Shireen Ultrasound Clinic Peshawar, Pakistan. This study enrolled a purposive sample of 162 patients presenting with abnormal uterine bleeding with the age between 18 to 80 years. The examination was performed with Toshiba Nemio 20(Xario Prime with TVS Probe frequency range 7-14MHz) .The Resistive index(RI), Pulsatility index(PI), mean and standard deviation were calculated for the continuous variables. Results: A total of 162 patients were enrolled in our study. The mean age of patients was recorded 38±5 years. In this study, the histopathological findings were as follow, 8.6% adenomyosis,12.3% endometrial hyperplasia, 43.3% leiomyoma’s, 17.3% polyp, 2.5% endometrial carcinoma and 16% non-specific findings so the most common cause of abnormal uterine bleeding was leiomyoma’s with mean of Right Uterine artery (U-A) PI and RI was 3.33±1.23 and 0.83±0.03 respectively and left U-A PI and RI was 2.95±1.17 and 0.84±0.03 respectively while the least common cause was endometrial carcinoma with mean of Right U-A PI and RI was 2.54±1.08 and 0.52±0.01 respectively and of Left U-A PI and RI was 1.62±0.00 and 0.52±0.00 respectively. Conclusion: From our study we concluded that the uterine artery RI in endometrial carcinoma causing abnormal uterine bleeding is low and in benign condition like polyp, hyperplasia and fibroids is high. Keywords: Uterine bleeding, Carcinoma, Fibroids, Hyperplasia, Trans-vaginal ultrasound
Comparison of Transvaginal Sonographic Doppler Indices Between Normal Intrauterine and Extrauterine Pregnancies Confirmed by Maternal Serum Beta-HCG in the First Trimester of Pregnancy
Authors: Ali Tayeba , Bacha Raham , Amin Saira , Farooq Syed Muhammad Yousaf , Fatima Mehreen , Manzor Iqra
Published: October 2022

Background: Transvaginal Sonography provides high-resolution images with high reliability and is typically used for the diagnosis of intrauterine pregnancy and ectopic conception. The extra-uterine pregnancy responsible for morbidity and mortality in First Trimester and is 80 percent accounts for maternal death. Doppler ultrasound is a safe and non-invasive technique in the evaluation of uterine artery flow patterns. It can calculate the indices like Resistivity index and Pulsatility index in numerical value. It is also observed that there are changes noted between the uterine artery indices in normal intrauterine and extrauterine pregnancies. However, it is important to compare them in normal intrauterine and extrauterine pregnancies. Objective: To compare the trans-vaginal sonographic Doppler indices of the uterine artery between normal and ectopic pregnancies confirmed by maternal serum Beta-hCG. Methodology: This case-control study was conducted at Shireen Ultrasound Clinic Peshawar, KPK Pakistan. This study enrolled a purposive sample of 80 (40 ectopic & 40 intrauterine) pregnant female patients with age 18 to 45 years. The examination was performed with Toshiba Nemio 20(Xario Prime with TVS Probe frequency range 7-14MHz). The Resistive index, Pulsatility index, mean and standard deviation were calculated for the continuous variables. Results: In normal early pregnancy, the mean RI of the right uterine artery was 0.53±0.10 and the mean RI of the left uterine artery was 0.52±0.07. In the cases of (ectopic pregnancy), the mean RI of the right uterine artery was 0.73±0.08 and the mean RI of the left uterine artery was 0.78±0.10. The p-value of the right and left uterine arteries in normal intrauterine and extrauterine ectopic pregnancies were significant at 0.05 level. Conclusion: The resistivity index of uterine arteries is significantly high in ectopic conceptions than in normal intrauterine pregnancies. But there was no significant change in PI of normal intrauterine and ectopic pregnancies. Keywords: adnexal mass, ectopic pregnancy, Transvaginal ultrasound, tubal pregnancy.
To Compare Outcome of Open Versus Laproscopic Repair for Primary Ventral Hernias
Authors: Khalid Sahibzada Saifullah , Amin Bahrul , Tahir Ahmad Arsalan , Khan Asad Ullah , Mustafa Muhammad , Alam Muhammad
Published: October 2022

Background: Primary ventral and incisional abdominal wall hernias are frequent conditions that necessitate surgery, and both types of hernias can be treated utilizing an open or laparoscopic technique. Improvements in laparoscopy have also been linked to a decrease in pain scores. Methodology: A dual setting study was conducted from July 2017 to June 2019 at Peshawar medical college with collaboration of Lady Reading Hospital and Hayatabd Medical Complex, Peshawar and was conducted on a total of 120 patients who were diagnosed with ventral hernia. A random number table created by a computer indicated repair of an open ventral hernia technique (group 1, n = 60) or laparoscopy (group 2, n = 60). Results: Among 60 patients in the laparoscopy group, there were 37 cases of PUH, 15 cases of epigastric hernia, 8 cases of umbilical hernia, and among 60 cases of open abdominal hernia, including 31 cases of PUH, 19 cases of hernia in the abdomen. upper abdomen, and 10 cases of umbilical hernia. Wound-related complications were most commonly seen in the open procedure group of patients. Conclusion: This has led to broad acceptance of the laparoscopic surgery, and advantages particularly in order to decrease the post-operative mortality and morbidity, time of operation, bleeding and the duration of hospital stay along the ability to execute the surgery on the obese people and with abdominal scarred individuals. Keywords: Incisional hernia, Laparoscopic mesh repair, Open mesh repair, Primary ventral hernia.
Compare Heart Rate Recovery and Cardiopulmonary Endurance of Badminton and Squash Player
Authors: Obaid Sumaiyah , Nasir Maham , Younis Ateeqa , Ahmad Mian Waleed , Ahmad Mian Awais , Khalid Nandisha , Zahra Fatima-Tul-
Published: October 2022

Background: Cardiopulmonary endurance is the ability to pump blood rich with oxygen to working muscles and this oxygen during exercise works and enhance period of activity. Regular aerobic exercises and sports can enhance cardiovascular endurance. Previous work in the field of physical science reveals that physical activity manage to advance and sustain higher levels of physical as well as cardiovascular fitness. Objectives: The main objectives of study were to compare heart rate recovery in badminton and squash healthy young adult players and to compare cardiopulmonary endurance among badminton and squash players. Methodology: 20 players with the age of 20-40 years playing badminton and squash for more than a yearfrom Liaquat Bagh Sports Complex, Rawalpindi were selected for this study. Subjects performed two tests for cardiopulmonary fitness testing i.e. Rockport walk test and 3 minutes step test. Subjects then played their regular game for 10 minutes. Heart rate, blood pressure, SpO2 were measured before the start of game, immediately after play and 5 minutes after cessation of game and heart rate recovery was calculated. Independent T test and Chi square test were applied to analyze the data. Results: When comparing heart rate recovery, results showed that people who were playing regular badminton showed faster heart rate recovery as compared to those individuals who were playing squash regularly. According to results of cardiopulmonary fitness test badminton players showed better result than squash players. Conclusion: Playing regular badminton for fitness purposes showed better results in cardiovascular health and heart rate recovery than playing squash Keywords: Badminton, Body Mass Index, Blood Pressure, Cardiopulmonary, Endurance, Heart Rate, Heart Rate Recovery, RatePerceived Exertion.
Comparison of Physical Activity Among Private and Public Undergraduates Medical Students
Authors: Ashfaq Mansab , Tariq Waleed , Ishfaq M. Ahsan , Khan Aliza , Hassan Mahnoor
Published: October 2022

Medical students and other health care professionals have substantial knowledge of the benefits of regular physical activity. Furthermore, as they have an ethical obligation to prescribe suitable exercises, they can influence their patients’ attitude toward physical activity and can become role models for their patients. Study design is cross-sectional. The questionnaire of research was distributed among 200 private medical students and 200 public medical students from different medical. Non Probability Convenience Sampling Technique was adopted to select the study population. International Physical Activity Questionnaire (IPAQ) (10) was developed which consists of different questions about their routine physical activities. Data was recorded anonymously, and we respected the confidentiality of the respondents. In our basic study there were a total of 400 medical. The study subjects included 26 % males and 74 % females in private sector and 19 % males and 81 % females in public sector. 29.5 % population belonged to 1st professional year and 70.5 % senior years in private sector whereas in public sector 69.5 % population belonged to 1st professional years and 30.5 % in senior years. The mean age of students is 21.9. And results obtained were not significant statistically and there was a lack in physical activity of both sectors almost on a par. The corresponding comparison of knowledge, attitude and practices of medical students between private and public sectors suggests that adequate knowledge about physical activity is not sufficient. There were a large number of medical students of both sectors who, despite being aware of benefits of physical activity, did not meet the recommended level of physical activity the reason as to why the results obtained were not significant statistically. Keywords: medical,physical,undergraduates,activity
Frequency of Musculosketelal Problems in Beauticians of Rawalpindi and Islamabad
Authors: Anjum Huda , Qazi Wardah , Rehman Hadiya , Shafique Muhammad Saad
Published: October 2022

Background: Many factors affect patient adherence to physical therapy treatment like unavailability of space and tools, lack of funding and awareness etc. Recognition of these barriers may help the physiotherapists to overcome these hurdles and ultimately improve treatment outcomes. The purpose of this study was to determine common MSK problems in beauticians, to identify the cause of MSK disorders, common spine deformity and awareness level of physical therapy among beauticians. Methodology: A descriptive cross-sectional survey was conducted using a self-structured questionnaire which was generated after literature review. 300 beauticians were considered for data collection. Result: Our study revealed that 59.9% of beauticians were having back pain,66% of them were having pain due to prolonged standing,49.3% of them were having normal posture,21.8% were having hyperextended knee and only 19% of them were aware of physical therapy treatment. Conclusion: It is concluded that the presence of back pain due to prolong standing was evident in beauticians. The most common MSK postural problem was found to be rounded shoulder. The awareness of physical therapy amongst beauticians was less evident and those who were aware were also not consulting physical therapists for their MSK problems. Keywords: beauticians, MSDs, posture, work-related disorders, musculoskeletal system.
Changes in Corneal Astigmatism after Closing Clear Corneal Incision by Simple Hydration Undergoing Phacoemulsification at the Department of Ophthalmology JPMC
Authors: Kanwal Maria , Tahir Muhammad Ali , Rabani Arif , Rehman Aziz Ur , Cheema Alyscia , Ateeq Asim
Published: October 2022

Purpose: To determine the mean changes of corneal astigmatism after closing clear corneal incision by simple hydration undergoing phacoemulsification in the eye department of a tertiary care hospital. Methodology: This was a Quasi experimental study conducted at the department of Ophthalmology, Jinnah Postgraduate Medical Center, Karachi, from 30th October 2020 to 29th April 2021. Total 100 patients who underwent phacoemulsification surgery for cataract were included. Changes of astigmatism were measured with Auto-refractometer. Fundus examination was done using +90D lens with a slit lamp. Mean changes in corneal astigmatism were calculated. Pre and post operatively change in astigmatism was compared using paired t-test. Stratification was done. P value ≤0.05 was considered as statistically significant. Results: Mean age was 43.47±11.13 years. There were 54% male and 46% female patients. Mean change of corneal astigmatism was 0.23±0.44 diopter. Mean corneal astigmatism, preoperatively, after 1 week and after 1 month were 1.05±0.05 diopter, 0.69±0.34 diopter and 1.28±0.44 diopter respectively. Highly significant mean difference of corneal astigmatism was observed between preoperatively and after 1 week, preoperatively and after 1 month and also observed between 1 week and 1 month. Conclusion: Closing clear corneal incision by simple hydration undergoing phacoemulsification was found an effective technique for treatment of corneal astigmatism. Keywords: Mean Changes, Corneal Astigmatism, Closing Clear Corneal Incision, Simple Hydration, Phacoemulsification
Tuboplasty/Tubal Surgery in the ERA of IVF
Authors: Sultana Ruqqia , Irum Sadia , Zafar Seemab , Nazir Qurat Ul Ain , Ijaz Omair
Published: October 2022

Aim: The detach of this research was to expand the relatively limited database on the efficiency of tubal surgery for the treatment of female sterility in Pakistan. Methodology: It was a qualitative descriptive series that took place at the Gynecology Unit of Ayub Teaching Hospital Abbottabad from May 2020 to April 2021. The research comprised 25 individuals who had tubal obstruction due to tubal illness or prior tubal ligation and were unwilling or unable to pay for assisted reproductive treatments. After a thorough assessment and evaluation of the pair, patients who presented with Fibroidectomy and azoospermia were eliminated from the research. Tuboplasty was performed on individuals utilizing open laparotomy procedures such as tubal excision and anastomosis, aerolysin, fimbriate, and salpingostomy. HSG examined the relatively brief result at three months and the lengthy result in the form of conceptions. The analytical program SPSS version 24 was used to look into the information. For constant factors like age and gender, standard deviations and means have been computed, whereas rates and percentages were determined for categorical data including such research outcomes. Results: Absolute effectiveness was reported in 11 patients (53%), with 8 (36%) produced owing to restoration of sterilization,2 (9%) produced after a combined of acheilia's as well as fimbriate on one side and salpingostomy on the other, and the second three (19%) produced after fimbriate and adhesiolysis. Conclusion: Tuboplasty proved effective in regaining fertility in individuals who were unable to afford IVF due to expense, societal standards, or religious principles. Keywords: Tuboplasty, IVF, Subfertility, Tubal patency test.