bluuebunny/crossref_metadata_2025 huggingface dataset:
Ouvindo a Voz do Mercado: O Varejo e os Clientes Portadores de Deficiência Auditiva
Authors: Meira Paulo Ricardo , Amaro Luiz Eduardo , Almeida Carolina Quadros
Published: March 2023

A presente pesquisa qualitativa busca subsídios para o entendimento de como o varejo pode satisfazer a necessidade de uma parcela de consumidores normalmente esquecida: os consumidores portadores de deficiência auditiva. É histórica no mundo negócios a recomendação druckeriana de que as empresas devam ser efetivas, contribuindo para uma sociedade melhor. Por outro lado, no aspecto de cidadania, uma melhor qualidade de vida pode ser produzida para segmentos da sociedade desprovidos da integralidade sensorial. Este projeto, baseado em metodologia de influência fenomenológica, explora a interface entre o papel das empresas e o consumo, enquanto interação social, ao analisar a qualidade das interações de consumo das pessoas portadoras de deficiência auditiva. Como resultado, identificou-se, efetivamente, diversas dificuldades dos clientes com deficiência auditiva nas suas interações de compra e, a partir disso, no final deste texto estão relacionadas algumas implicações gerenciais.
Consumo Ecológico entre as Mulheres: Análise de Antecedentes
Authors: Battistella Luciana Flores , Grohmann Márcia Zampieri , Mello Carolina Iuva , Radons Daiane Lindner
Published: March 2023

Neste estudo busca a conhecer as crenças, comportamento e consumo ecológicos entre as mulheres. Os modelos utilizados foram de Dunlap & Van Liere, (1978) e RSW Green Gauge (Ottman, 1998), ambos estudados previamente por Pikett-Baker e Ozaki (2008). Nessa pesquisa, o ajuste do modelo, através da fatorial confirmatória, foi satisfatório. Foram testadas seis hipóteses de relações causais. Os resultados demonstraram que: as crenças ambientais apresentam relação com o consumo ecológico e o comportamento ecológico possui relação com o consumo ecológico.
O posicionamento epistemológico das pesquisas brasileiras no campo da estratégia voltadas às instituições de ensino superior.
Authors: Heinzen Daiane Aparecida de Melo , Marinho Sidnei Vieira , Nascimento Sabrina do
Published: March 2023

Este artigo tem por objetivo analisar o posicionamento epistemológico das pesquisas brasileiras no campo da estratégia, voltadas às instituições de ensino superior (IES) por meio de um estudo bibliométrico nos periódicos nacionais classificados pela Qualis/CAPES nos estratos “A1”, “A2” e “B1” da área de Administração, Ciências Contábeis e Turismo, correspondente ao último triênio de 2012, além dos anais da Associação Nacional dos Programas de Pós-Graduação em Administração (ANPAD), no período de 1999 a 2011. A amostra deste estudo é composta por 14 artigos científicos que abordam a temática “Instituição de Ensino Superior” e “Estratégia”. Na metodologia, optou-se por uma pesquisa documental por meio de uma pesquisa bibliométrica e, para análise dos dados, realizou-se uma abordagem quantitativa das informações dispostas nos artigos científicos e uma breve análise de conteúdo. Conclui-se, a partir dos resultados, uma carência de pesquisas que abordam esta temática no cenário nacional e as poucas pesquisas existentes apresentam um posicionamento epistemológico predominantemente positivista a partir de uma perspectiva objetivista e de cunho quantitativo. Ressalta-se, ainda, que o autor da área de estratégia mais referenciado foi Mintzberg.
Empreendedoras escrevem a própria história: estudo realizado a partir do teste de complemento de frases.
Authors: Ferreira Jane Mendes , Rese Natália , Nogueira Eloy Eros
Published: March 2023

Objetivo deste artigo é apresentar o teste de complemento de frases como um aliado nas pesquisas de cunho qualitativo, comprometidas com os pressupostos da teoria sócio-histórica. Esta possibilidade apresenta-se tanto como um método de pesquisa quanto como uma abordagem. A base teórica é a teoria da subjetividade de González Rey que trata da relação dialética entre polos interno-externo, intra-intersubjetivo, trazendo os conceitos de subjetividade individual e social. Ao fazer isso, o pensador cubano coloca no centro da análise a concepção de configurações subjetivas. Para alcançar o objetivo foi realizada uma pesquisa operacionalizando o instrumento proposto e demonstrando sua utilidade para pesquisas de cunho qualitativo. Tal ação permitiu chegar às seguintes considerações a respeito do empreendedorismo feminino: i) empreendedores se auto referenciam; ii) a família e os negócios são imbricados; iii) o empreendedorismo não é maniqueísta; iv) a ação empreendedora assume o caráter de um fim em si mesmo; v) a atividade empreendedora é uma atividade de feitos heroicos; e vi) a visão sobre a mulher ainda é naturalizada. De forma, geral, ao viver e empreender elas constroem suas identidades, quebram alguns padrões e reforçam outros e se constituem sujeitos da própria história. Elas vivem o empreendedorismo no seu dia-a-dia, na concretude de sua experiência, e, sem diluir-se em grupos protetores, guardam sua configuração subjetiva de forma única. Palavras-chaves: Complemento de Frases; Subjetividade, Empreendedorismo.
Fatores de Influência no Desempenho em Redes de Colaboração Interorganizacional Horizontal: Um Estudo no Segmento de Autopeças
Authors: Xavier Filho Jose Lindenberg Julião , Soares Francisco de Assis , Dos Santos Sandra Maria , Cabral Augusto Cézar de Aquino , Pessoa Maria Naíula Monteiro , Roldan Vivianne Pereira Salas
Published: March 2023

O segmento do aftermarket de autopeças nacional vive uma profunda mudança em seus canais de distribuição, comprimindo a figura do varejo que, para responder a tais mudanças, tem se unido e constituído diversas ações, dentre elas a formação da Rede Âncora de Autopeças. As redes de colaboração interorganizacional têm o potencial de contribuir para a competitividade das empresas que a integram, uma vez que permitem acesso a informações, recursos, mercados e tecnologias, que ampliam as vantagens econômicas no tocante ao aprendizado, às escalas e escopo de produção ou de comercialização. Nesse contexto, o objetivo geral deste trabalho foi verificar a influência dos fatores estruturais e relacionais na percepção do desempenho pelos gestores das empresas que integram a Rede Âncora de Pernambuco. Trata-se de uma pesquisa de natureza explicativa, com abordagem quantitativa. Foi realizada  uma pesquisa de campo junto às empresas participantes dessa rede, sendo utilizados como instrumentos de coleta um questionário aplicado junto aos gestores dessa empresas e uma entrevista semi-estruturada com o atual presidente da Rede Âncora de Pernambuco.  Para o tratamento dos dados advindos do questionário, foram usadas estatística descritiva e regressão múltipla. Na análise da regressão múltipla, foi utilizado o modelo o recíproco uma vez que a literatura não apontava um modelo empírico já testado. Com os resultados obtidos, confirma-se estatisticamente a relação entre a dimensão estrutural e a dimensão relacional com o desempenho percebido pelos gestores.
Condições Causais e Efeitos Físicos, Cognitivos e Sociais do Uso da Internet por Idosos: Um Estudo Netnográfico em Redes de Comunicação On-line
Authors: Godoi Christiane Kleinübing , Machado Vanessa Vieira , Mastella Adriano
Published: March 2023

Uma combinação de fatores, tais como, dificuldades físicas, mentais, educacionais e situação econômica são responsáveis pela exclusão dos idosos da tecnologia da informação. Estudos anteriores indicam que a Internet pode contribuir para o movimento de inclusão social dos idosos. Tomando as redes de comunicação online - fundamentalmente as comunidades virtuais - como objeto, este estudo objetiva compreender os impactos físicos, cognitivos e sociais gerados pelo uso da Internet por idosos. A estratégia de pesquisa utilizada foi a netnografia – termo cunhado por Kozinets, em 1998 – que surgiu do encontro entre a antropologia e cibercultura com a finalidade de estudar o imaginário virtual e seus atores, por meio da observação participante. Realizou-se o monitoramento sistemático de comunidades virtuais puras – aquelas se estabelecem somente pela mediação do computador, especificamente, trabalhou-se com a comunidade Orkut. O estudo identificou quatro tipos de causas que funcionam como obstáculo ao acesso dos idosos à Internet, sendo três de ordem cognitiva: a Dificuldade de Compreensão; o Disfarce de Identidade; a Deconfiança; e a Escassez de Idosos que Utilizam a Internet. Acerca dos impactos de efeito negativo produzidos pelo uso da Internet, entre aqueles que já utilizam a rede, foram encontrados os seguintes fatores: Conseqüências Físicas; Diminuição das Relações Presenciais, bem como, inúmeros outros fatores de impacto positivo, tais como, a Redução do Sentimento de Solidão; o Resgate de Antigas Amizades, e a oportunidade de Novas Aprendizagens por meio da tecnologia e de reingresso ao universo do conhecimento – fatores importantes no processo de inclusão social dos idosos.
Geração de valor na cadeia de suprimentos: um teste empírico das funções diretas e indiretas no fomento de relacionamentos business to business
Authors: Luiz Adão Alves , Monteiro Plínio Rafael Reis , Moura Tiago Bastos
Published: March 2023

Este artigo busca compreender como as funções que determinam a geração de valor interagem como variáveis relacionais e atuam no fortalecimento dos elos entre fornecedores e compradores, sob uma perspectiva business to business, na cadeia de suprimentos. O objetivo foi verificar a influência das funções diretas e indiretas de valor sobre a satisfação, a confiança e o comprometimento e seu impacto na intenção de manutenção de relacionamentos e de comunicação positiva entre uma rede varejista e seus fornecedores. A metodologia compreende a concepção de um modelo de marketing de relacionamento voltado ao comércio varejista supermercadista que contempla construtos relacionais típicos e as funções diretas e indiretas de geração de valor. A coleta de dados foi realizada através de um questionário on-line aplicado aos fornecedores ativos do supermercado estudado, resultando em 109 respostas. Os resultados suportam 12 hipóteses do total de 21 propostas de acordo com a revisão da literatura. Os achados demonstram que a qualidade do processo, o comportamento unilateral e as funções de valor direto do relacionamento são o ponto de partida para a construção de relacionamentos duradouros com os fornecedores, sendo a confiança e o comprometimento os mediadores-chave para fomentar relacionamentos e promover uma imagem positiva para a rede de supermercados.
IDENTIDADES CULTURAIS DE CONSUMIDORES DA PITÚ EM SUA COMUNIDADE DE MARCA: UMA NETNOGRAFIA DA COMUNICAÇÃO
Authors: Leão André Luiz Maranhão de Souza , Camargo Thiago Ianatoni , Cavalcanti Rodrigo César Tavares
Published: March 2023

Hoje em dia o consumo tem papel fundamental no processo de construção de identidades. Nessa dinâmica, a marca se tornou um signo pelo qual os indivíduos se apresentam uns para os outros. Paralelamente, os avanços na tecnologia dão origem a ambientes virtuais onde diferentes pessoas interagem em torno de assuntos que lhes interessam. Com base nisto, o presente artigo tem por objetivo analisar como consumidores da Pitú constroem identidades culturais em interações sociais ocorridas em uma comunidade virtual da marca. Para tal, realizamos uma netnografia da comunicação das interações ocorridas na comunidade. A partir de uma análise do discurso funcional que toma por base a noção de relações de equivalências e diferenças, foram encontradas seis identidades culturais de consumidores. Os resultados contribuem com a academia ao apresentarem uma diferente visão de como as relações humanas podem ser mediadas pelas marcas. Por outro lado, os achados também servem de base para o gerenciamento de marcas e marketing de relacionamento.
TRANSPARÊNCIA NO PODER LEGISLATIVO MUNICIPAL: UMA ANÁLISE DOS PORTAIS ELETRÔNICOS DAS CÂMARAS DE VEREADORES DAS CAPITAIS BRASILEIRAS
Authors: Campagnoni Mariana , Carvalho Rodrigo Dornelles , Lyrio Maurício Vasconcellos Leão , Lunkes Rogério João , Rosa Fabrícia Silva da
Published: March 2023

O presente artigo se insere no contexto do uso das Tecnologias de Informação e Comunicação no setor público, objetivando verificar e analisar os níveis de transparência apresentados pelos portais eletrônicos das Câmaras de Vereadores das capitais brasileiras. Em relação à sua metodologia, a pesquisa possui caráter descritivo, com abordagem qualitativa e quantitativa. Para a coleta de dados, observaram-se as informações apresentadas nos portais da transparência das Câmaras de Vereadores com base em um modelo multicritério de avaliação proposto por Nunes (2013). A amostra é constituída por 24 capitais nacionais. Os resultados apontam níveis de transparência aquém do que se espera em relação a Câmaras de Vereadores de capitais brasileiras. Com relação aos 24 municípios analisados, 54,17% apresentaram portais com nível de transparência insuficiente para disponibilização de informações de interesse da população. Conclui-se que o conteúdo apresentado nos portais da transparência, em geral, tendem a cumprir mínimo exigido pela lei, mas com pouco indício de maiores incentivos à participação popular e à promoção da accountability.
ANÁLISE DE VIABILIDADE ECONÔMICA DOS ESTÁDIOS DA COPA DO MUNDO FIFA 2014
Authors: Barros Thiago de Sousa
Published: March 2023

Este artigo busca apresentar um estudo de viabilidade econômica das doze arenas multiuso da Copa do Mundo FIFA 2014, que aconteceu no Brasil durante os meses de junho e julho. Para este efeito, foram utilizados os métodos convencionais de avaliação de investimento – Projeções de Fluxo de Caixa, o Valor Presente Líquido (VPL) e Taxa Interna de Retorno (TIR). Ademais, foi realizada uma análise de sensibilidade dos projetos em relação a variações do cenário econômico. Os resultados apontam que as arenas Pernambuco, Beira Rio e Baixada se mostraram economicamente viáveis, enquanto o Maracanã apresenta viabilidade somente em alguns cenários: quando há aumento das receitas ou redução do investimento. Os demais estádios se mostraram como projetos sem viabilidade, o que enfatiza os prejuízos que deverão ser assumidos pelo Estado e a importância de se utilizar essas ferramentas de engenharia econômica no processo de decisão de investimento, pois evita aplicação de capital em empreendimentos não rentáveis e de alto risco.
Cooperative quantum information erasure
Authors: Buffoni Lorenzo , Campisi Michele
Published: March 2023

We demonstrate an information erasure protocol that resets N qubits at once. The method displays exceptional performances in terms of energy cost (it operates nearly at Landauer energy cost kTln⁡2), time duration (∼μs) and erasure success rate (∼99,9%). The method departs from the standard algorithmic cooling paradigm by exploiting cooperative effects associated to the mechanism of spontaneous symmetry breaking which are amplified by quantum tunnelling phenomena. Such cooperative quantum erasure protocol is experimentally demonstrated on a commercial quantum annealer and could be readily applied in next generation hybrid gate-based/quantum-annealing quantum computers, for fast, effective, and energy efficient initialisation of quantum processing units.
Их номч багш Намсрайн Содном
Authors: О Лхагва
Published: March 2023

Цэг мэтэд хурсан гаргууд нягтрая дэлбэрч үүссэн бараагүй холхи цагаас инагш ирчлон урт ужиг хувьслыг туулжээ. Хүмүүний оюун ухаан, нийгмийн өрнөлийн өнөөгийн өндөрлөгт хүртэл дэвжихдээ хорвоогийн түг түмэн юмс нь тасралтгүй төрлийг олох хийгээд бас түүнийг арилжсаар иржээ. Нөгөөтэйгүүр атом, цөмийн ертөнцийн зүй жамыг судлах хувь тохиосон бидний хэн маань ч аливаа юмс, үзэгдэл хязгаартай огторгуйд, төгсгөлөг хугацаанд бүрэлдэж. хувирдагийг гүнээ мэдэрдэг билээ.
Создание и исследование стримерной камеры-мишени с лазерным освещением для излучения взаймодействий элементарных частиц
Authors: С Энхбат
Published: March 2023

Использование трекового детектора с лазерной стримерной камерой повышенного давления в магнитном поле позволит детально исследовать угловые распределения и угловые корреляции заряженных и нейтральных частиц, а также их импульсные спектры. В качество мишени используется газ, наполняющий камеру, что даст возможность наблюдать взаимодействие с вылетом даже малоэнергичных частиц и регистрировать акты взаимодействия пионов с ядрами водорода, дейтерия, гелия - 3, гелия — 4 и углерода.
Coal structure in the oxidation
Authors: S Munkhtsetseg , B Munkh-Orchlon
Published: March 2023

In the current paper we present the experimental results of Nuurstkhotgor coals in the original (as received) and with low temperature treatment and compared those experimental with the theoretical ones for the observing coal molecule structure specifics in the oxidation. Three groups of the paramagnetic centres are responsible for one narrow Lorentz 1 (0.18 mT), three broad Gaussian 1 and 2 (0.30-0.62 mT), three broadest Gaussian 3 and 4 (0.85-1.05 mT) lines found in the EPR spectrums in the two coal samples. An infrared spectrum obtained experimentally from the heated coal has established several differences from the spectra of the original coal by its number of the bands and the intensities. Main differences are located in the 3000 and 1000 cm-1 absorption region where the vibrations from the O-H and C-O bonding.
Дейтрон Дээр Явагдах Фото Урвалуудын Огтлолын Туршлагын Дүнг Шалгах Асуудалд
Authors: Б Отгоолой , Г Дамдинсүрэн , Д Баатархүү
Published: March 2023

Цэвэр ус H2O болон хүнд ус D2O-ыг тормозын гамма цацрагийн ижилхэн урсгалд шарсан. Фото протоноор явагдах O16(p,a) N13 урвалаар үүссэн N13 (Т1/2=9,97минут )цацраг идэвхт изотопын бета идэвхжилийн хугацаанаас хамаарлыг ус ба хүнд усны хувьд хэмжсэн .Эдгээр дээжний идэвхжилийн харьцаагаар дейтрон дээр явагдах фото урвалуудын огтлолд үнэлгээ өгсөн.
Микротрон Дээр Гамма-Нейтроны Холимог Орноор Шарах Төхөөрөмж
Authors: Б Отгоолой , П Зузаан , Г Дамдинсүрэн
Published: March 2023

Энэ ажлаар МТ-22 микротроны гамма суваг дээр нейтрон болон гамма цацрагаар нэгэн зэрэг судалгаа хийхэдзориулсан төхөөрөмжийн хамгийн тохиромжтой геометрийн болон бүтцийн тооцоонуудыг хийж, зохион бүтээсэн. Төхөөрөмжийн үндсэн физик үзүүлэлтүүдыг бүрэн тодорхойлсон. Энэхүү төхөөрөмж зохион бүтээгдсэнээр гамма болон нейтроноор явагдах зарим цөмийн урвалуудын огтлолыг харьцангуй аргаар, нэг элементийг хоёр аргаар зэрэг тодорхойлох шинэ аргууд боловсруулсан. Энэ ажлыг “Хрэглэгээний цөмийн физикийн судалгаа” сэдэвт ажлын хүрээнд гүйцэтгэв.
Улаанбаатар орчмын агаар мандлын оптик зузааны судалгааны зарим үр дүн
Authors: Т Нарангарав , Г Батсүх
Published: March 2023

Энэ ажлаар шилэн шүүлтүүрүүд бүхий актинометрээр Улаанбаатарт 1979-2009 онд хийсэн нарны шулуун цацрагийн хэмжилтээр спектрийн фотосинтезийн идэвхит цацраг (ФИЦ, 380нм≤λ<710нм), биологийн идэвхит цацраг (БИЦ, λ≤510нм) болон инфра улаан цацраг (ИУЦ, λ≥710нм)-ийн муж дахь агаар мандлын оптик зузааныг нарны өндрийн янз бүрийн утганд жилийн улирал бүрт тодорхойлон тэдгээрийн дундаж утгыг үнэлэв. Тухайн нутаг дахь агаар мандлын оптик зузааны жилийн турш дахь өөрчлөлтийг спектрийн дээрх муж тус бүрт гарган харуулав.
Хурдан нейтроны үйлчлэлээр цөмөөс альфа бөөм гарах урвалын энерги
Authors: Ж Бадамсамбуу , Г Хүүхэнхүү
Published: March 2023

Цөмийн урвалын статистик загварт тулгуурлан гаргасан (n,α) урвалын огтлолын томъёонууд дахь С, К параметрүүдийг үнэлэв. Эдгээр параметрүүдээ ашиглан (n,α) урвалын энергийг бодож туршлагын утгуудтай харьцуулав.
Ургамлын фитометрийн үзүүлэлтүүд
Authors: Д Аззаяа , Э Эрдэнэбат
Published: March 2023

Агро цаг уурын судалгаанд ургамлын фитометрийн үзүүлэлтүүдийг 1990 оны үеэс тодорхойлж эхэлсэн билээ. Ургамлын фитометрийн үзүүлэлтүүдэд ургамлын өндөр, ишний урт, эрхтнүүдийн (иш, навч, түрүү г.м) талбай, жин, ургамлын ногоон ба шар хэсгийн эзлэх хувь зэрэг орно. Энэхүү ажилд Агро цаг уурын шинжилгээний Дархан станцад хийгдсэн ургамлын фитометрийн ажиглаптын дүнг нэгтгэн тэдгээр үзүүлэлтүүдийн хандлагыг судлах зорилго тавилаа.
Effectiveness of Gong’s Mobilization Over Myofascial Release Technique in Patients with Adhesive Capsulitis.
Authors: Challey Tilling , Dutta2 Abhijit , Kalita Abhijit , Pyngrope4 Hormot Ryniaw
Published: March 2023

Adhesive Capsulitis, also known as frozen shoulder, is a severe condition of the shoulder characterized by pain, severe stiffness and restriction of movements in the shoulder joint. We aim to evaluate the effect of Gong's Mobilization with conventional therapy versus the Myofascial release technique with conventional treatment in subjects with Adhesive capsulitis; Objectives that were assessed are Shoulder pain, disability and range of motion. Thirty subjects completed the study. The subjects were randomly assigned into two groups. Group A Received Gong's Mobilization with conventional therapy, and Group B received Myofascial Release technique with traditional treatment. Both groups received ten intervention sessions (5 sessions/week) in 2 weeks. Outcome Parameters: Pain intensity was measured by Visual Analogue Scale (VAS), ROM of the shoulder by universal goniometer & functional disability by shoulder pain and disability index (SPADI). These parameters were measured pre-intervention and after ten sessions of intervention. Analysis using paired t-test and independent-test found no statistically significant difference (p<0.05) between Gong's mobilization with the conventional therapy group and Myofascial release technique with the traditional group of therapy on improving pain, ROM and decreasing the functional deficit. Gong's mobilization with conventional therapy and Myofascial release with the standard treatment technique with conventional therapy is equally effective in improving pain and ROM and decreasing the functional deficit.
Evaluating structural relations between money demand and its determinants
Authors: Umoru David , Effiong Solomon Edem , Ugbaka Malachy Ashywel , Iyaji Danjuma , Okpara Enyinna , Ihuoma Chineleobi Chris , Tedunjaiye Olawale Hezekiah , Omoluabi Ehis Taiwo , Omomoh Oseni Hussein
Published: March 2023

The relationship between money demand and specific macroeconomic predictors has been explained by a number of money demand theories. Panel structural vector autoregressive (SVAR) and generalized autoregressive conditional heteroskedasticity (GARCH) techniques were deployed to analyze the data on money demand with lag adjustment in relation to inflation uncertainty, interest rate variations, household consumption, and exchange rate depreciation in Africa. The study which covers 30 African nations discovered a two way relationship between money demand and price level variation. While higher prices would increase demand for money, the same demand also influences changes in a nation’s price level, such that in the long run, inflation would result from more money held by economic units. With a standard deviation of 5.51, Guinea had the most erratic money demand, followed by Sierra Leone at 5.29. A variance of inflation uncertainty ranged from 9.45 percent to an extremely high proportion for Congo. Exchange rate devaluation is found to be considerably impactful in determining money demand. Results show that as more of the units of the local currency is used to exchange a unit of foreign currency such as the dollar, local economic units are discouraged to increase demand for money in local money and thus hold fewer local currencies while investing in foreign exchange investments
Severe burn-induced mitochondria recruitment of calpain causes aberrant of mitochondrial dynamics and heart dysfunction
Authors: Zhou Jing-Jun , Ran-Ran Zhang , Jing-Long Zhang , Qiao Li , Shu-Miao Zhang , Gu Xiao-Ming , Wen Niu , Lyu-Chen Zhou
Published: March 2023

Mitochondria damage is an important cause of heart dysfunction after
severe burn. However, the pathophysiological process remains unclear.
This study aims to examine the mitochondrial dynamics in the heart after
severe burn, and the role of μ-calpain, a cysteine protease, in this
scenario. Rats were subjected to thermal injury treatment, and calpain
inhibitor MDL28170 was given intravenously 1 h before burn injury.
Compared with the sham group, the rats in the burn group displayed
weakened heart performance and decreased mean arterial pressure, which
was accompanied by a diminishment of mitochondria function. Furthermore,
severe burn increased the level of calpain in mitochondria, reflected by
immunofluorescence staining and activity test. In contrast, treatment
with MDL28170 diminished these responses to a severe burn. Severe burn
induced morphological defects of mitochondria, and decreased the
abundance of mitochondria. Of note, severe burn increased the percentage
of the mitochondria with bigger size, but decreased the smaller ones.
Analysis of dynamic proteins revealed that severe burn caused an
increase of fission protein DRP1 in the mitochondria and a decrease of
inner membrane fusion protein OPA1. Similarly, these alterations were
also blocked by MDL28170. Last but not the least, inhibition of calpain
yielded the emergence of more elongated mitochondria along with membrane
invagination in the middle of the longitude, an indicator of the fission
process. Overall, these results for the first time provide evidence that
mitochondria recruitment of calpain confers heart dysfunction after
severe burn, which involves mitochondrial dynamics damage.
Dissociations between spontaneous EEG features and the Perturbational Complexity Index in the minimally conscious state
Authors: Casarotto Silvia , Hassan Gabriel , Rosanova Mario , Sarasso Simone , Derchi Chiara-Camilla , Trimarchi Pietro , Viganò Alessandro , Russo Simone , Fecchio Matteo , Devalle Guya , Navarro Jorge , Massimini Marcello , Comanducci Angela
Published: March 2023

The analysis of spontaneous EEG is a cornerstone in the assessment of
patients with disorders of consciousness (DoC). Alterations in specific
frequency bands have been reported, including a predominance of delta
power in vegetative state/unresponsive wakefulness syndrome (VS/UWS)
patients in contrast with a predominance of alpha activity in minimally
conscious state patients (MCS). Although preserved EEG patterns are
highly suggestive of consciousness even in unresponsive patients,
moderately or severely abnormal patterns are difficult to interpret.
Indeed, growing evidence shows that consciousness can be present despite
either large delta or reduced alpha activity in spontaneous EEG.
Quantifying the complexity of EEG responses to direct cortical
perturbations (Perturbational Complexity Index; PCI) may complement the
observational approach and provide a reliable assessment of
consciousness even when spontaneous EEG features are inconclusive. To
systematically test this hypothesis, we compared PCI to EEG spectral
measures in the same population of MCS patients (n=40) hospitalized in
rehabilitation facilities. We found a remarkable EEG background
variability across MCS patients as compared to healthy controls and a
non-negligible number of patients with predominant delta and highly
reduced alpha power in spontaneous EEG. Conversely, PCI values
invariably suggested a capacity for consciousness in all MCS patients,
consistent with the presence of clearly discernible, albeit fleeting,
behavioral signs of awareness. These results confirm that spontaneous
EEG rhythms may dissociate from the actual capacity for consciousness
and suggest that a perturbational approach can effectively compensate
for this pitfall with practical implications for the individual
patient’s stratification and tailored rehabilitation.
Impact of an Integrative Clinical Pharmacy Model on the Occurrence of Complications in Patients implanted with a PICC Line
Authors: POUGET Alix Marie , MOUNIE Michael , LEPAGE Benoît , CIVADE Elodie , CESTAC Philippe , MOLINIER Laurent , ROUZAUD-LABORDE Charlotte
Published: March 2023

Background Clinical pharmacy is an effective pharmaceutical discipline
in drug therapy management and in preventing iatrogenic events. Clinical
pharmacy studies in the medical device context are, however, rare in the
current literature. Purpose The purpose of this study is to prove that
clinical pharmacy is effective in the medical device context by reducing
PICC line complications post-implantation. Methods CLIPICC is a
prospective before-and-after single-centre study conducted in a
University Hospital. The study comprised two successive phases: an
initial observational phase (OP), where no clinical pharmacy activities
were carried out, followed by an interventional phase (IP), where
clinical pharmacy activities were implemented along the patient’s
hospital and primary care pathway. The key outcome of the study was the
number of complications per month and per patient in each phase.
Comparisons were made using negative binomial regression. Univariate and
multivariate analyses were performed with R software. Results A total of
138 patients were enrolled in the study. In the OP, 40 patients (59.7%)
presented at least one complication with 80 complications being recorded
overall in 67 patients. In the IP, 30 patients (45.5%) had at least one
complication with a total of 39 complications documented in 66 patients.
The number of complications per patient and per month was halved in the
interventional phase. Conclusion Clinical pharmacy interventions along
the entire care pathway are effective in preventing complications
following implantation of PICC lines. Trial registration: NCT04359056.
Transforming Lives: How Comprehensive Community-Based Rehabilitation Hospital in Tanzania is Combating Obstetric Fistula.
Authors: Kessy Ambrose T. , Madale Mpamila M.
Published: March 2023

Obstetric fistula (OF) is a physically and psychologically debilitating
medical condition that impacts vulnerable women in Tanzania. It occurs
primarily as a result of prolonged labor, which leads to the formation
of an abnormal opening between the bladder or rectum and the vagina, and
can cause severe incontinence, stigma, and social isolation.
Non-governmental organizations (NGOs) have been instrumental in
providing assistance and support to vulnerable women with obstetric
fistula in Tanzania. This study investigated the various interventions
implemented by NGOs in Tanzania to help women suffering from obstetric
fistula. The study aimed to identify the strategies employed by NGOs to
address obstetric fistula among vulnerable women, as well as explore
factors that influence the delivery of obstetric fistula services. By
using the Comprehensive Community-Based Rehabilitation in Tanzania
(CCBRT) as a case study, the study establishes that Tanzania’s largest
provider of fistula surgery (CCBRT) has implemented various initiatives,
including expansion of joint delivery services, an m-pesa mobile
outreach program, an ambassadorial network, and an improvement of
service quality, to assist vulnerable women, particularly those in
remote areas. The study concludes that obstetric fistula is a
debilitating condition that continues to affect vulnerable women in
Tanzania, and NGOs have played a critical role in providing
interventions to alleviate the impact of this condition on women in the
country.
A managerial approach in resource allocation models: An application in US and Canadian oil and gas companies
Authors: Mohamadinejad Hengameh , Amirteimoori Alireza , Kordrostami Sohrab , Hosseinzadeh Lotfi
Published: March 2023

In resource allocation and target setting problems, a central decision
makers? managerial standpoint has a pivotal role, especially when we
encounter undesirable outputs such as the greenhouse gas (GHG) emissions. In
such circumstances, firms have to cooperate with each other, to achieve the
central planner?s aims. Looking into literature reveals that the existing
resource allocation models based on data envelopment analysis (DEA) have not
aptly considered the influence of managerial efforts and technological
innovations in this sense. This study proposes a centralized model
incorporating managerial disposability. This model not only reflects the
leadership performance of the central planner and the technological novelty
perspective in the resource allocation and target setting problem, but also
has a positive modification against an environmental adaptation change. In
order to illustrate the applicability of our resource allocation and target
setting model, a case study of 23 US and Canadian oil and gas companies has
been conducted. Analysis of the results reveals the appropriacy and
efficiency of our proposed model in dealing with the current perspectives
concerning the issue of resource allocation and target setting.
Implicit Tax, Tax Incidence, and Pretax Returns
Authors: Guenther David A. , Sansing Richard C.
Published: March 2023

We investigate the relation between tax rates and pretax returns by showing how implicit tax, tax incidence, and tax capitalization change in response to a tax rate change. We examine these issues in the context of both financial assets and real investments made by corporations in a competitive equilibrium in which all investments earn the same after-tax rate of return. Results show that the pretax return increases in the statutory tax rate due to an explicit tax rate effect and decreases due to a cost of capital effect; the net effect is ambiguous. In contrast, the implicit tax rate is weakly increasing in the statutory tax rate. We also relate our findings to the empirical literature on the effects of taxes on pretax returns.

JEL Classifications: H22; H25.
Structural Racism as an Upstream Social Determinant of Diabetes Outcomes: A Scoping Review
Authors: Egede Leonard E. , Campbell Jennifer A. , Walker Rebekah J. , Linde Sebastian
Published: March 2023

OBJECTIVE

To evaluate the evidence on the role of structural racism as an upstream factor impacting diabetes outcomes, identify current gaps, and recommend areas for future work.

RESEARCH DESIGN AND METHODS

A reproducible search of Medline and Ovid was used. Structural factors based on the World Health Organization social determinants of health framework (governance, macroeconomic policy, social policy, public policy, and cultural and societal values) had to be included as measured variables or contextual factors discussed as upstream influences. Outcomes included 1) hemoglobin A1c (HbA1c), 2) LDL, 3) BMI, 4) quality of life, 5) self-efficacy, 6) mortality, 7) years of life lost, and 8) self-care behaviors.

RESULTS

Thirteen articles were included for final synthesis. Ten studies focused on governance, two on social policies, one on public policies, and one on cultural and societal values. Results highlight significant associations between structural racism and poorer clinical outcomes (HbA1c and blood pressure), worse self-care behaviors (diet and physical activity), lower standards of care, higher mortality, and more years of life lost for adults with diabetes.

CONCLUSIONS

There is a paucity of work investigating the relationship between structural racism and diabetes outcomes. Five areas for future work include 1) more rigorous research on the relationship between structural racism, downstream social determinants, and health outcomes in diabetes, 2) policy assessments specific to diabetes outcomes, 3) research designed to examine pathways and mechanisms of influence, 4) intervention development to mitigate the impact of structural racism, and 5) tracking and monitoring of change over time.
O PROCESSAMENTO SENSORIAL E A APRENDIZAGEM DE CRIANÇAS COM TEA DURANTE A PANDEMIA POR COVID-19
Authors: Maia Joycy Beatriz Moreira , Lustosa Ana Valéria Marques Fortes
Published: March 2023

O processamento sensorial constitui elemento imprescindível para compreender o Transtorno do Espectro Autista. Não obstante essa consideração, observa-se que há poucos estudos relativos ao tema na área da educação. O presente estudo consiste em uma parte do resultado de dissertação, e teve como objetivo compreender como o ensino remoto afetou o processo de aprendizagem e o processamento sensorial de crianças com TEA. Este trabalho foi realizado seguindo uma abordagem qualitativa e, como instrumento de coleta de dados foi adotada a entrevista semiestruturada com 11 familiares que acompanharam suas crianças com TEA no ensino remoto emergencial durante a pandemia de COVID-19. Como resultado, foi possível constatar que as crianças enfrentaram diferentes dificuldades decorrentes da quebra de rotina, como perda de habilidade e aumento das crises devido ao desafio que foi conviver com estímulos relacionados ao consumo de tela diariamente, com objetivo de promover a aprendizagem, dentro do ambiente domiciliar.
Influence of Cigarette Smoking on Liver Function and Lipids Levels Tests: A comparative Study Directed among Smokers and Non-smokers in Babylon Governorate
Authors: Al-Mousawi Haider Turky Mousa , Ali Alia Hussein , Hashim Nadhim
Published: March 2023

Cigarette smoking currently is considered as one of the greatest problems in public health worldwide and is risk factor for peripheral vascular disorders and heart disease. The monitoring of liver function and total cholesterol are very important to give an estimation of the future cardiovascular diseases among smokers. The objective of this study is to evaluate the effect of cigarette smoking on the serum levels of liver enzymes: aspartate aminotransferase (GOT), alanine transaminase (GPT) and cholesterol activities among Iraqi smokers in Babylon City, compared to apparently healthy individuals (non-smokers) as a control group (all were males). A case- control study was carried out on forty Iraqi male smokers who smoke at least 10 cigarettes per day for at least15 years. The group includes smokers with age range between 15-55 years. Non-smokers, (control, n= 20) group were collected with the same range of age for statistical comparison.  The whole blood samples were drawn by venipuncture from each individual; levels of cholesterol and liver functions test were estimated in the blood serum of smokers and non-smokers by diagnostic kit (Randox corporation-UK) using automatic analyzer.The findings of this study showed that there was a significant higher level of total cholesterol, ALT, and AST in the smokers group compared to non-smokers (P<0.05). As well as, the results showed a significant positive correlation between the smokers’ age and serum GOT, GPT and cholesterol activity (Increasing) especially in age between 45 to 55 years old, as compared to control. In addition, total cholesterol and liver function enzymes were significantly positive correlated with the duration of smoking (P<0.05).Cigarette smoking leads to oxidative stress by free radical generation by the mechanism of lipid peroxidation that is affected by the heaviness of smoking. Smoking exerts negative influence on liver functions test that should be carefully interpreted and preventive strategies needed to avoid the future cardiovascular diseases.
Hematological Regulation Using β-aminobutyric Acid In Staphylococcus aureus infected Rats
Authors: Agab Zainab , Jasim Mohammed A. , Zgair Atheer
Published: March 2023

Several studies have directed the use of different chemicals as an antibiotics alternative that kills bacteria or may lead to stimulating the body's resistance against infections, such as organic acids that include non-protein amino acids especially β-aminobutyric acid (ΒABA), which  has proven in this study its ability  to increase  the systemic resistance of male rats against  Staphylococcus aureus. As well as increasing the numbers of white blood cells and lymphocytes and their positive effect on improving the immune complement system . The aim of study was to know the effect of  β-aminobutyric Acid on the response immune system of animals that was infected  with   s. aureus bacteria

Objectives of the study

Study of hematological parameters of animals treated with BABA, including:

WBC ,RBC , Hb , PCV ,LYM ,GRA

 

 

Materials used in  this experiment mannitol salt field, as well as blood agar and MacConkey agar were used for the development of Staphylococcus aureus bacteria, as well as amino acid β-aminobutyric Acid with different concentrations

Prepare the first solution of amino acid concentration (20 mg/ml).The other amino acid was prepared at a concentration of (40 mg/ml)Then the required doses for each animal were prepared according to the weight of each animal

Results:

The effect of BABA on the level of  (RBC – WBC – PLT –LYM –GRA)

The results showed that there was no effect of the amino acid BABA on the level of (RBC-MCV-PLT) in groups infected with bacteria and treated with BABAThe results showed that there was no effect of the amino acid BABA on the level of (WBC) in the groups infected with bacteria and treated with BABA, while the percentage of (LYM-GRA) increased.
The effect of Alloxan induced diabetes on baseline comet test in male laboratory mice fed on different feeding systems
Authors: Hassan Mina N. , Hussein Ferial F. , Al-Ahmad Hazem I.
Published: March 2023

Background: The comet analysis (electromagnetic relay analysis of a single cell) is ahighly sensitive method for determining DNA damage because to exposure tocarcinogens and other substances that consequently affect fertility.Objective: the aim of this study is to Evaluation the broken DNA in male diabeticmice. Created by alloxan and knowledge of the effect of some nutritional systems onthe treatment and repair of genetic material due to diabetes.Materials and methods: In this study were used, 42 male Albino mice labs at the ageof 2-3 months and weight (25-30) g then 6 animals were isolated to represent thecontrol group, The remaining animals were injected between the thighs by alloxan 150mg / kg and left the next day to make sure hit by diabetes and randomly distributed tosix groups in addition to a set of Not affected control transactions.Results and conclusion: It was found from the results of the statistical analysis shownin figure(1) showed the presence of the highest percentage of injuries in the geneticmaterial that was in the group of animals with diabetes and untreated for the durationof the experiment, as it was clear from the photos of this group that the tail lengthresulting from the migration of the genetic material DNA to outside the nucleusbecause to its damage, as well as the results showed that the group of animals affectedby diabetes and the treatment by adding the Salvia officinalis plant to both plant andanimal nutrition had a significant decrease (<0.05> P) in the proportion of geneticmaterial injuries where the proportion of high (long guilt) infections was low in thesetwo The two groups compared to the group of animals with diabetes and untreated forthe duration of the experiment.
Kinetic and thermodynamic aspects of the process of thermal inactivition of kluyveromyces marxianus inulinase
Authors: Коvаlеvа Т.А. , Taha Abdul Sattar J. , Abdulaziz Firas A. , Al-Dhahir Rashid k.
Published: March 2023

Background: Inulinase is widely found in microorganisms and higher plants. It catalyzes the reaction of the hydrolysis of inulin, which is present in the tubers and roots of many plants, to fructose and a small amount of glucose.

Inulin is one of several plant-based polysaccharides that contain glucose or fructose. It is used as a substrate in industrial fermentation processes and in the food industry due to its relatively cheap and abundant source for the microbiological production of high fructose juices, ethanol, acetone and butanol. Inulin-derived oligosaccharides are also used in the medical and food sectors. Inulinase which produced from the yeast K. marxianus at levels close to commercial use. This indicates that inulinase can be used in the production of fructose and fructose syrups. So our main object is to study the effect of different temperatures on the conformation of the Kluyveromyces marxianus inulinase macromolecule, to provide optimal conditions for aniline hydrolysis by inulinase.

Materials and method: Method of isolation and purification of the inulinase enzyme from Kluyveromyces marxianus, as well as the determination of the protein content and enzyme activity as mentioned in the context of the research. Experiments were carried out to study the thermal stability of enzyme. For this, an enzyme solution at a concentration of 5•10-5 mol / l was incubated in a time interval of 10-60 min at different temperatures, followed by determination of the catalytic activity.

It is known that different types of bonds and interactions participate in the formation of the molecular structure of enzymes, which are covalent bonds, hydrogen bonds, salt bridges, hydrophobic interactions, so our main goal is to study the effect of different temperatures on the formation of the enzyme molecule in order to provide optimal conditions for aniline hydrolysis. by enzyme.

Results: of this study revealed that the residual activity of the enzyme after 60 minutes of incubation at 50 °C was 10% of the initial activity at 60 °C 7%. As for the Rate Constants of thermal inactivation of Inulinase at 70 °C were 3.45.

Conclusions: Results of this study were important and useful in determining parameters of inulinase enzyme. Based on the shape of the curves of the dependence of the catalytic activity of Kluyveromyces marxianus inulinase on the time of thermal inactivation in the temperature range of 20-80 ° C.
Study to investigate the concentration of sodium in bread for some Baghdad bakeries
Authors: Dawood Abdulsalam T. , Thabit Zaid A. , Shlahi Sattar A. , AL-Ahmed Hazim I . , Salman Israa H.
Published: March 2023

Cardiovascular disease is the leading cause of premature death due to dietaryfactors such as high salt intake. Bread is one of the most important of these sources, asit causes high blood pressure. In this study, 48 samples of three types of bread werecollected from different bakeries in Baghdad regions, namely white bread, brownbread and local bread, with an average of 16 samples for each type. This study is thefirst in Iraq for the purpose of determining the level of sodium concentration added tothe three types of bread. The aim of this study is to establish the approved controlsand standards for adding sodium to bread. The sodium concentration in the samplesmentioned in this study was calculated, using a dedicated sodium concentration kit,produced by Agappe Diagnostics Switzerland. The maximum value of SodiumConcentration for white bread was in AlShaeb Region (3.555gm), while themaximum value of the Sodium Concentration for the Barley Bread type was in theAlghazalia region (3.518gm) and Mahmudiyah (3.496gm) .The maximum value forthe Sodium Concentration was for the third type, which is the local Bread in theAssadar City region (3.604gm).and the a minimum value of the SodiumConcentration for white bread was in Abu Ghareeb region (3.099gm), while the aminimum value of the Sodium Concentration for the Barley Bread type was in theAbu Ghareeb region (3.093gm) , Palestine Str. (3.133gm) And Karrada region(3.188gm ) and the a minimum value of the Sodium Concentration for Local Breadwas in Palestine Str. (3.186gm) and Abu Ghareeb region (3.208gm).Keywords: white bread, brown bread, local bread, Sodium Concentration