bluuebunny/crossref_metadata_2025 huggingface dataset:
Two cases of hepatoblastoma with neonatal necrotizing enterocolitis
Authors: He Sidou , Wang Xisi , Duan Chao , Zhao Wen , JIANG CHIYI , Zhang Shihan , Jian Binglin , yang wei , Yu Tong , Fu libing , Wang Huanmin , Ma Xiaoli
Published: March 2022

Hepatoblastoma (HB) is the most common liver malignant tumor in
childhood and is related to premature delivery and low birth weight.
Neonatal necrotizing enterocolitis (NEC) is also related to premature
delivery and low birth weight. We report two patients who were diagnosed
as hepatoblastoma after having a history of NEC, and they are not common
in hepatoblastoma due to their particularity. Premature delivery and low
birth weight are the common factors leading to the onset of HB and NEC.
The correlation between the two needs further study.
Communities, ecosystem engineers, and functional domains
Authors: Ponge Jean-Francois
Published: March 2022

Communities are shaped by the activity of ecosystem engineers, which
modify their environment to their benefit and that of subordinate
species within their functional domain. Communities are defined as
embedded assemblages of interactions, from cells to landscapes. They are
threatened by present-day global changes which trigger the invasive
nature of ecological engineers, with cascading effects.
Limited evidence of vertical root segregation in a subtropical forest
Authors: Luo Wenqi , Ni Ming , Wang Youshi , Lan Run , Eissenstat David , Cahill James , Li Buhang , Chu Chengjin
Published: March 2022

Vertical root segregation can be a key underpinning of species
co-existence through below-ground niche partitioning but has rarely been
tested in diverse forest communities. We randomly sampled >
4000 root samples from 625 0-30 cm soil profiles in a subtropical forest
in China to determine the degree of vertical root segregation among 109
woody species and rooting plasticity in response to edaphic
heterogeneity and root neighbours. Over 85% of species were
predominantly distributed in the 0-10 cm soil zone, exhibiting low and
inconsistent rooting plasticity in response to either edaphic
heterogeneity or root neighbours. There was no evidence of vertical root
segregation among co-occurring species. Contrastingly, the increase of
one species’ root abundance tended to increase, but not reduce other
species’ root abundance within soil zones. These findings suggest that
interspecific differentiation of resource acquisition strategies might
be more important than root segregation in mediating species
co-existence in diverse forests.
LAPAROSCOPY ASSISTED ABDOMINAL COLPOPEXY: (PROPOSED) GOKHALE TECHNIQUE: NOVEL AND SIMPLE TECHNIQUE FOR PREVENTION AND TREATMENT OF VAULT PROLAPSE : A SURGICAL TECHNIQUE Dr Asha Niranjan Gokhale Department of Obstetrics & Gynecology , Deenanath Mangeshkar Hospital and research center, Pune, Maharashtra, India ashagokhale17@gmail.com
Authors: Gokhale Asha
Published: March 2022

The gold standard technique for treatment of vault prolapse is a
laparoscopic sacro colpopexy, which requires advanced surgical skill in
endoscopy. We present a new surgical technique for treatment of vault
prolapse namely “laparoscopic assisted abdominal colpopexy “. This
technique involves skills of a vaginal surgery and basic skill of
laparoscopy to give an option for treatment of vault prolapse at lesser
equipped centers. Technique involves suspension of vaginal vault by
fixing mersilene tape vaginally and guiding It under laparoscopic vision
extraperitoneally to anchor it to inturned part of inguinal ligament
near the anterior superior ischial spine.
Combining QTL mapping and transcriptomics to decipher the genetic architecture of phenolic compounds metabolism in a conifer
Authors: Laoué Justine , Depardieu Claire , Gérardi Sébastien , Lamothe Manuel , Bomal Claude , Azaiez Aida , Gros-Louis Marie-Claude , Boyle Brian , Hammerbacher Almuth , Isabel Nathalie , Bousquet Jean
Published: March 2022

Conifer forests worldwide are becoming increasingly vulnerable to the
effects of climate change. Although phenolic compounds (PCs) have been
shown to be modulated by biotic and abiotic stresses, the genetic basis
underlying the variation in their basal composition remains poorly
documented in conifers. We used QTL mapping and RNA-Seq to explore the
complex polygenic network underlying the constitutive production of PCs
in white spruce (Picea glauca) full-sib progeny for two years. QTL
detection was conducted for nine PCs and differentially expressed genes
(DEGs) were identified between individuals with high and low PC contents
for five PCs exhibiting stable QTLs across time. A total of 17 QTLs were
detected for eight metabolites, including one major QTL explaining up to
91.3% of the neolignan-2 variance. The RNA-Seq analysis highlighted 50
DEGs associated with phenylpropanoid biosynthesis, several key
transcription factors, and 137 genes showing opposite expression
patterns in individuals with high levels of the flavonoids gallocatechin
and taxifolin glucoside. A total of 19 DEGs co-localised with QTLs. Our
findings represent a significant step towards resolving the genomic
architecture of PC production in spruce and enhancing the functional
characterization of genes and transcriptional networks responsible for
differences in constitutive production of PCs in conifers.
Aging Kinetics on Silver-Functionalized Silica Aerogel in Off-Gas Streams including Dry Air, Humid Air, NO and NO2
Authors: Choi Seungrag , Nan Yue , Tavlarides Lawrence
Published: March 2022

Aging impact on silver-functionalized silica aerogel
(Ag-aerogel) in the off-gas streams including dry
air, humid air, 1% NO/N, and 2%
NO/dry air were studied. Aged
Ag-aerogel was prepared through a continuous-flow
aging system by exposing Ag-aerogel (unaged) to the
off-gas streams at different aging temperatures and time. Iodine loading
capacity on the aged Ag-aerogel was obtained through
a continuous-flow adsorption system. Iodine loading capacity losses were
observed after the Ag-aerogel was exposed to the
off-gas streams. Characterization studies were conducted to observe the
physical and chemical changes of the Ag-aerogel after
exposed to gas streams. According to iodine adsorption data and
analyses, it was revealed that iodine loading capacity on the aged
Ag-aerogel in the off-gas streams decreases with
increasing aging temperatures and time. The pseudo reaction model
describes experimental data well and the oxidation of
Ag is the rate determining step in the aging process.
Lorentzian signatures and Quantum Kerr-(A)Ds Galilean Myers–Perr driven gravitational transformations for the anti-COVID-19 RoccuffirnaTM evolutionary drug design.
Authors: Grigoriadis Ioannis
Published: March 2022

It is thought that all of the rich content in the present-day Universe
based on an array of recent observations developed through gravitational
amplification of primeval density fluctuations generated in the very
early phase of cosmic evolution. In this paper, we strongly combine
machine learning characteristics to achieve very high accuracy levels
for the in-silico generation of the RoccuffirnaTM small molecule, a
ligand targeted the SARS-COV-2 virus main protease (M pro ) using
Quantum Kerr-(A)dS and Myers–Perry black microBlackHole-Inspired
Gravitational for both Euclidean and Lorentzian signatures in Practice.
We provide also an extensive toolbox of methods for performing quantum
schrodinger inspired docking algorithms, teleportation and other
information-theoretic tasks in MathCast programming language, and
compared these algorithms by means of mean percentile free energy
ranking, in a new recall-based evaluation metric for the in-silico
design of the Novel Series of the RoccuffirnTMQMMMCoRoNNARRFr
anti-(nCoV-19) ligands. In this paper we in-silico designed new drug
leads that target the COVID-19 virus main protease (M pro ). M pro, a
key CoV enzyme, which plays a pivotal role in mediating viral
replication and transcription, and discuss various general results
including Galilean transformation to a rigid QMMM heuristic horizon
topology, and near-horizon fragmentation symmetry ranging from
supergravity theories to Lorentzian signatures in order to enhance the
Roccuffirna’s gravity to trap the SARS-COV-2 viruses in practice.
Re-emergence of Avian leukosis virus subgroup J in the rooster of Hy-line brown and its transmission pattern in flocks
Authors: Meng Fanfeng , Li Qiuchen , Gao Xintao , Luo Fubing , Liu Xiaodong , Shen Guangnian , Zhang Zhifang , Zhang Guozhong , Zhao Peng
Published: March 2022

Avian leukosis virus subgroup J (ALV-J) is the most prevalent subgroup
in chickens and exhibits increasing pathogenicity and stronger
horizontal and vertical transmission ability in different kinds of
chicken. Although vertical transmission of ALV-J from hens infected
through artificial insemination with ALV-J infected semen was reported
before by the detection of swabs and serum, there was no further
research on the trasmission pattern of ALVs in the roosters. In the
present study, the introduction of Hy-line brown roosters infected with
ALV-J significantly increased the p27 positive rate of ALV in a
indigenous flock detected by virus isolation. Sequence analysis and IFA
showed that it is classified into ALV-J subgroup, locating in a new
branch compared with the domestic and foreign referential sequences.
Meanwhile, the gp85 gene of the ALV-J isolated in the hens and its
albumens had a homology of 94.1-99.7% with that in the roosters, which
means that the strain is quite likely transmitted to the hens and their
offspring through insemination of the roosters. Moreover, Semens are
directly detected by ELISA method is not completely accurate. There are
four ALV-J infection status in plasma and semen of rooster (V+S+, V-S+,
V+S-, V-S-), so the eradication of ALV in rooster requires simultaneous
virus isolation of semen and plasma. Therefore, we speculate that the
reason why there are still some sporadic findings of ALV-J in laying
hens is probably due to the incomplete eradication process of roosters.
ECTHYMA GANGRENOSUM IN CHILDREN WITH CANCER: DIAGNOSIS AT A GLANCE. A retrospective study form the Infection Working Group of Italian Pediatric Hematology Oncology Association.
Authors: Muggeo Paola , Zama Daniele , Decembrino Nunzia , Onofrillo Daniela , Frenos Stefano , Colombini Antonella , Perruccio Katia , Calore Elisabetta , Giurici Nagua , Ficara Monica , Spina Milena La , Mura Rosamaria , Santis Raffaela De , Santoro Nicola , Cesaro Simone
Published: March 2022

Purpose. To describe ecthyma gangrenosum (EG) characteristics and
complications in a large multicenter pediatric retrospective collection
of children with malignancies or bone marrow failure syndromes. Methods.
EG episodes diagnosed in the period 2009-2019 were identified by a
retrospective review of clinical charts at centers belonging to the
Italian Pediatric Hematology Oncology Association. Results. EG occurred
in 38 children (male/female 16/22; median age 5.2 years) with
hematological malignancy (33), allogeneic stem cell transplantation (2)
or relapsed/refractory solid tumor (3). The involved sites were:
perineal region (19), limbs (10), trunk (6), head and the iliac crest
(3). Bacteremia was present in 22 patients. Overall, the germs isolated
were Pseudomonas aeruginosa (34), Stenotrophomonas maltophilia (3) and
Escherichia Coli (1); 31% of them were MDR. All patients received
antibacterial treatment while surgery was performed in 24 patients
(63.1%). Predisposing underlying conditions for EG were: severe
neutropenia (97.3%), corticosteroid treatment (71%), iatrogenic
diabetes (23.7%). All patients recovered, but EG recurred in 5
patients. Nine patients (24%) showed sequelae (deep scars, with muscle
atrophy in 2). Four patients (10.5%) died, 1 due to relapse of EG with
KPC co-infection, 3 due to the underlying disease. Conclusions. EG
requires early recognition and a proper and timely treatment to obtain
the recovery and to avoid larger necrotic evolution. The occurrence of
scarring sequelae might affect the quality of life of patients.
Plant regeneration through somatic embryogenesis in two cultigroups of Pineapple (Ananas comosus L.)
Authors: Cacaï Gilles , Ahokpossi Brunith A.M. , Houédjissin Serge S. , Houngue Jerome Anani , Badou Bienvenue T. , Ahanhanzo Corneille
Published: March 2022

Pineapple production is mostly constrained by unavailability of
high-performance suckers. However, somatic embryogenesis (SE) have been
revealed the most rapid and controllable method for Pineapple
propagation than conventional sucker production methods. The aim of this
study was to evaluate the responses of two cultivars of pineapple
regenerated through somatic embryogenesis. Thus, calli were induced from
crown leaf and plantlets leaf of Smooth Cayenne and Sugar Loaf
cultivars. Murashige and Skoog base medium supplemented with vitamins B5
and different in hormonal combinations: Auxins / Cytokins. BAP and / or
2,4-D have been added to base medium for calli maturation and BAP and
GA3 for plant regeneration. The results indicated a significant
influence of type of explant and copper on callus induction in pineaple
cultivars. Likewise, The medium MS with growth regulator combination NAA
(0.5 mg/l) + BAP (1mg / l (BAP) has a highly significant influence with
8.8 mature somatic embryos. Also, the growth regulator combinations and
the cultivars have significantly influenced somatic embryos regeneration
with a high rate of 55.25% shoots by using the hormonal combination BAP
(3 mg/l) + GA3 (2 mg/l) for the smooth Cayenne. The protocol developed
is a key study for successful mass propagation of the pineapple and
genetics transformation of pineapple.
An unusual Presentation of Rheumatoid Arthritis with a two years bilateral Knee swelling in a young Sero-negative patient; A case report
Authors: saad abubakr gumaa balal , Essa Mohammed Elmujtba Adam , Moawia Walied , Babker Atif Elhadi Abdalla , Hassan Abubkar
Published: March 2022

Rheumatoid arthritis (RA) is an autoimmune multi-systemic inflammatory
disease affecting joints result in dysfunction and ultimately damage,
seronegative RA has the clinical manifestations but negative diagnostic
markers of RA. A 24 years old male presented with bilateral knee
swelling.
Desarrollo de sistemas de fertirriego por goteo superficial localizado en el cultivo de gulupa bajo invernadero
Authors: Carvajal Caballero Rubén
Published: March 2022

En el sector fruticola con fines de exportación en la provincia de García Rovira, en el departamento de Santander, se presentan niveles bajos de eficiencia en el uso del agua y los nutrientes que se suministran a cultivos como la uchuva, el maracuyá, la granadilla y para el caso específico del presente documento la gulupa. Al respecto, en los municipios de Concepción y Molagavita se llevó a cabo el diseño y la implementación de sistemas de fertirriego por goteo localizado superficial en el cultivo de gulupa bajo invernadero. Primero se realizó el diseño del sistema de riego que permite la distribución uniforme del agua mediante el goteo y posteriormente, se efectuó la dosificación de la nutrición mineral necesaria para el cultivo de acuerdo con su etapa fenológica y los requerimientos nutricionales para tener un plan de riego y fertilización adecuado para su posterior aplicación mediante el fertirriego. Como resultado se logró el establecimiento de 4 modelos en Concepción y 2 en Molagavita que promueven la mejora del proceso productivo y así obtener mayor productividad y mejores oportunidades de acceso a mercados y las condiciones socioeconómicas del productor. Se busca que a través del proceso de extensión tecnológico liderado por el Centro Agroempresarial y Turístico de los Andes (SENA-Málaga) replicar los modelos descritos para generar mayor productividad y competitividad de los productos obtenidos en los proyectos productivos de los agricultores e impulsar así, el sector fruticola en García Rovira.
Desarrollo del turismo en el Huila: Situación actual 2021 y desafíos futuros
Authors: Mora Natalia , Vargas Marby , Trujillo Lina
Published: March 2022

El turismo se menciona a menudo como uno de los principales motores del desarrollo económico en el departamento del Huila. Esto como resultado de una nueva concepción del mundo globalizado, facilidad de acceso a la información, mejores ingresos y mayor disponibilidad de tiempo que designan las personas para viajar y descubrir nuevos destinos. En ese sentido y dada la importancia del turismo para la economía regional, se hace necesario conocer de primera mano el estado actual del turismo después de la pandemia, así como analizar las tendencias del mercado turístico nacional e internacional con el fin de obtener información significativa, completa y oportuna para el entorno turístico regional altamente cambiante y complejo, lo cual será de gran consideración a la hora de tomar decisiones asertivas que permitan reactivar y estimular el mejoramiento y/o crecimiento de este sector económico en el departamento.
Declaratorias repetidas en los discursos políticos latinoamericanos
Authors: Herrera Diego
Published: March 2022

Entre las declaratorias más repetidas en los discursos políticos latinoamericanos están frases como “la salud es un derecho”, pero esto no es completamente cierto. Existen determinantes que junto a las condiciones socioeconómicas propias de los países en vías de desarrollo, ponen en duda la universalidad de esta aseveración.
Actualización Covid 19: terapia ambulatoria y variantes
Authors: Gaus David
Published: March 2022

Se realiza una actualización del conocimiento medico científico sobre el COVID-19 en relación, a la farmacología, tratamiento ambulatorio, y variantes.
PEMBEKALAN KETERAMPILAN KERAJINAN TANGAN DAN MANAJEMEN USAHA KREATIF PADA IBU-IBU RUMAH TANGGA
Authors: Agustina Yenni
Published: March 2022

Ibu-ibu rumah tangga memiliki peranan yang penting dalam membantu perekonomian keluarga.  Pemberdayaan masyarakat khususnya kaum wanita dalam kegatan ekonomi kreatif dapat memberikan dampak yang sangat besar dalam mengurangi angka tingkat kemiskinan sebagai salah satu dampak dari pandemi covid 19.  Fenomena ini terjadi di hampir di setiap Negara tak terkecuali Bandar Lampung khususnya kecamatan Kedamaian.  Kecamatan Kedamaian merupakan kecamatan yang berlokasi sangat strategis karena berdekatan dengan pusat pemerintahan kota Bandar Lampung.  Permasalahan ekonomi yang melanda tentu saja memerlukan solusi yang tepat salah satunya yaitu dengan pemberdayaan kaum perempuan melalui kegiatan ekonomi kreatif.  Kurangnya keterampilan akan pembuatan produk yang bernilai jual tentu saja menjadi kendala tersendri bagi kaum wanita untuk dapat berdikari dalam kegiatan ekonomi kreatif, selain itu juga kendala masih lemahnya wawasan manajemen usaha seperti cara memperoleh modal akibat masih minimnya modal atau ketidak tersediaan modal, pemasaran barang, hingga pembukuan laporan keuangan.  Oleh karena itu, pemberdayaan wanita sangat diperlukan dalam masyarakat untuk mengurangi angka tingkat kemiskinan melalui kegiatan PkM, sehingga diharapkan kegiatan ini dapat menjadi awalan akan berkembangnya ekonomi kreatif di wilayah tersebut.  Kegiatan PkM dilakukan di RT 015 kelurahan Tanjung Raya dengan ibu-ibu pkk yang berjumlah sebanyak 10 orang sebagai peserta dalam kegiatan pengabdian ini.  Kegiatan ini menggunakan bahan sisa seperti botol kaca menjadi produk yang bernilai guna dengan mengolah menjadi decoupage.

 

Kata Kunci: Pemberdayaan Perempuan, Ekonomi Kreatif, Manajemen Usaha, Decoupage
PENYULUHAN MANAJEMEN REPRODUKSI DAN KESEHATAN SERTA PENGOBATAN MASSAL TERNAK SAPI DI DESA PURWOREJO, KECAMATAN NEGERI KATON, KABUPATEN PESAWARAN
Authors: Sirat Muhammad Mirandy Pratama , Hartono Madi , Ermawati Ratna , Santosa Purnama Edy , Nisak Rohmatin , Regisa Adek Rayhan , Irawan Bayu Hadi Setya , Widowati Mia , Hardiyanti Cici , Hanafi Riyan
Published: March 2022

Peternakan sapi rakyat merupakan salah satu penopang ekonomi di Provinsi Lampung namun kondisi tatalaksana manajemen reproduksi dan kesehatannya belum optimal sehingga terjadi gangguan reproduksi dan kesehatan ternak. Desa Purworejo, Kecamatan Negeri Katon, Kabupaten Pesawaran, Provinsi Lampung merupakan salah satu desa yang masyarakatnya banyak memelihara sapi. Berdasarkan survei pendahuluan tampak bahwa pengetahuan dan wawasan peternak tentang manajemen reproduksi dan kesehatan sehingga produktivitas ternak sapi masih rendah. Tim Pengabdian Kepada Masyarakat melalui penyuluhan terkait manajemen reproduksi dan kesehatan sapi bertujuan meningkatkan pengetahuan, pemahaman serta cara pemeliharaan ternak rakyat secara konvensional menjadi berbasis ilmu pengetahuan dan meningkatkan kesehatan ternak melalui pengobatan massal ternak. Sasaran kegiatan pengabdian ini yaitu masyarakat peternak sapi di Desa Purworejo Kecamatan Negeri Katon Kabupaten Pesawaran. Kegiatan pengabdian ini dilakukan dengan metode 1) Penyuluhan meliputi kegiatan penyuluhan dan diskusi mengenai manajemen reproduks dan kesehatan; dan 2) Pemeriksaan kesehatan dan pengobatan massal ternak sapi. Evaluasi kegiatan dilakukan untuk mengetahui sejauh mana respon peserta penyuluhan terhadap pelaksanaan kegiatan pengabdian dengan cara membandingkan perubahan nilai pada evaluasi awal (pre-test) dan evaluasi akhir (post-test). Kesimpulan kegiatan ini yaitu 1) kegiatan penyuluhan diikuti oleh 14 peternak dengan pemeriksaan kesehatan dan pengobatan massal dilakukan pada 23 ekor sapi; dan 2) kegiatan pengabdian masyarakat meningkatkan pengetahuan dan kemampuan peternak dengan skor tinggi pada sisi pengetahuan kesehatan ternak sapi sebesar 86,43%; sisi reproduksi sebesar 82,86%; dan sisi pengetahuan sanitasi kandang sapi sebesar 91,27%.
Feline gastrointestinal eosinophilic sclerosing fibroplasia
Authors:   Animal Sciences Faculty, University of Nariño, Pasto, Colombia, Enríquez Montenegro Nicolás , Ríos Castro Diana A. ,   Animal Sciences Faculty, University of Nariño, Pasto, Colombia, Bedoya López Paola A. , Chaves Velásquez Carlos A. , Paz Calvache Tatiana G. ,   Animal Sciences Faculty, University of Nariño, Pasto, Colombia,   Animal Sciences Faculty, University of Nariño, Pasto, Colombia
Published: March 2022

A female Persian cat arrives for clinical assessment with a 3-month history of weight loss and sporadic vomiting. The clinical and paraclinical findings were hypodynamia cachexia, leukocytosis and presence of a mass in duodenum. Histopathological evaluation revealed a non-neoplastic tumor proliferation, which was organized into dense, sclerotic-like connective tissue trabeculae that anastomosed, with cells of spindle-shaped morphology, elongated and rounded nuclei with prominent nucleoli and fine granular chromatin. These cells were intermingled with abundant eosinophils and in smaller proportion lymphocytes, macrophages, plasma cells, with transmural distribution. Masson's trichrome differential staining trabeculae of collagen fibers. Based on the clinical and microscopic findings, the diagnosis of feline eosinophilic sclerosing fibroplasia is established, being this pathology’s first documented report in Colombia.
Oleander (Nerium oleander) intoxication in a bison
Authors:   California Animal Health and Food Safety Laboratory System, San Bernardino Branch, University of California-Davis, Streitenberger Nicolás , Asin Javier ,   California Animal Health and Food Safety Laboratory System, San Bernardino Branch, University of California-Davis, Navarro Mauricio A. ,   Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Poppenga Robert H. ,   California Animal Health and Food Safety Laboratory System, Davis Branch, University of California-Davis, Uzal Francisco A. ,   California Animal Health and Food Safety Laboratory System, San Bernardino Branch, University of California-Davis
Published: March 2022

Clinical History: Two 18-month-old female bison and a heifer died suddenly in the same ranch. The three animals were submitted for postmortem examination and diagnostic workup. The changes of one of the bison are presented here. Necropsy Findings: The carcass was in fair nutritional condition, with small amount of fat reserves, but still well fleshed, and in mild state of post-mortem decomposition. There was a small amount of clotted dark-red blood in the nostrils and anus. The heart presented extensive sub-endocardial hemorrhages in all four chambers. These lesions were most pronounced in both ventricles where they extended deep into the underlying myocardium (Figs. 1 and 2). The mucosa of the abomasum was diffusely and mildly congested, and the mucosa of the small and large intestine was diffusely and severely congested (Fig. 3). There was a moderate amount of red fluid in the lumen of the small intestine, cecum, and colon. Both lungs had a few, small, welldelineated, deep, firm, multifocal dark-red areas in all pulmonary lobes, but lung tissue samples floated when placed into formalin.
Analisis Berpikir Aljabar dan Kesalahan Peserta Didik dalam Menyelesaikan Soal Pemecahan Masalah pada Materi SPLDV
Authors: Kosasih Nadia Zulfa
Published: March 2022

Tujuan penelitian ini untuk menganalisis kemampuan berpikir aljabar dan kesalahan peserta didik dalam menyelesaikan soal pemecahan masalah pada materi sistem persamaan linear dua variabel. Penelitian ini menggunakan metode penelitian kualitatif. Teknik pengumpulan data menggunakan triangulasi dengan pemberian soal tes, wawancara secara tidak terstruktur dan menulis catatan lapangan. Instrumen utamanya peneliti sendiri dengan instrumen bantuan soal tes dan catatan lapangan. Sumber data penelitian peserta didik kelas 8 SMP Negeri 6 Tasikmalaya yang melakukan kesalahan dalam menyelesaikan soal pemecahan masalah pada materi aljabar. Teknik analisis data yang dilakukan dimulai dari reduksi data, penyajian data, dan penarikan kesimpulan. Berdasarkan hasil penelitian ini dikemukakan bahwa pada kemampuan berpikir aljabar peserta didik tidak memenuhi indikator generasional, diakibatkan oleh kesalahan prosedural, dan pada indikator transformasional peserta didik dinilai memenuhi karena mampu melakukan kedua aktivitas yang ada, untuk indikator level-meta global peserta didik tidak memenuhi karena tidak mampu melakukan aktivitas pemecahan masalah menemukan konsep penyelesaian, hal ini diakibatkan oleh kesalahan konseptual
Artificial Neural Network Training Algorithm for Factor-Based Prediction of Electricity Consumption in the Household Sector
Authors:   Tajik Technical University named after Academician M.S., TAVAROV Saidjon Sh.
Published: March 2022

An analysis of the known methods for forecasting electricity consumption in urban distribution electric networks has shown that they are all based on the availability of sources of both electric and thermal energy. Reduction or complete absence of heat sources leads to significant forecast errors, which entails a drop in the energy efficiency of urban electrical networks and degraded reliability of power supply system individual components. Theoretical, computer, and neural network models that help achieve more accurate forecasting of electricity consumption in the household sector are proposed. Based on the developed mathematical model and taking into account the factor coefficients obtained for 2020 for nine cities of the Republic of Tajikistan, monthly values of the coefficient characterizing the terrain conditions were calculated. The results obtained using the proposed mathematical model were compared with the data of computer and neural network models. A method that helps obtain more accurate forecasting of electricity consumption in the household sector is proposed. To automate the monitoring and control of electricity generated by renewable energy sources, an algorithm for training an artificial neural network for factor-based forecasting of electricity consumption is proposed, the use of which will help improve the forecasting accuracy owing to the possibility of constantly training the neural network. The algorithm efficiency is confirmed by good agreement between the results obtained both using the proposed models and based on the readings of electricity meters.
Combating DDoS Cyberattacks in the Energy Sector
Authors:   Nizhny Novgorod State Technical University n.a. R.E. Alekseev, DMITRIEV Dmitriy V. , LYAKHMANOV Dmitriy A. ,   Nizhny Novgorod State Technical University n.a. R.E. Alekseev, SOKOLOVA Eleonora S. ,   Nizhny Novgorod State Technical University n.a. R.E. Alekseev
Published: March 2022

Digitalization of infrastructures with the use of information technologies for efficient intelligent management of power systems and their having rather poor cybersecurity are factors provoking a growing number of cyberattacks in the energy sector. At the same time, the energy sector structural units are critically important facilities malfunctioning of which compromises the national security. The problem has become so serious that cyberattacks on the energy sector infrastructural facilities are seen by the governments of many states as real threats leading to malfunctioning of the fuel and energy complex facilities. There is a steady growth of distributed denial-of-service (DDoS) attacks targeted on energy sector facilities. Electric energy building and control automation systems and call centers of power generating companies are attacked, causing power supply to entire regions become upset for a long period of time. At present, there are no reliable and universal technologies capable to block DDoS attacks. The article describes a method for combating DDoS attacks in power systems based on non-semantic filtering of traffic. The article also presents a new approach to combating DDoS attacks, which protects servers and traffic bandwidth. The proposed approach is based on the interaction of users with server equipment by dynamically changing the IP addresses of the attacked resources according to a pseudo-randomly generated schedule. The developed technology for filtering the network traffic makes it possible to combat DDoS attacks, reducing their intensity by about 92 %. As a result, the loss of legitimate packets, which is unavoidable in implementing any DDoS combating technology, makes less than 2 %.
Minimization of Technical Active Power Losses in Extra-High Voltage Overhead Power Lines Taking the Corona Effect into Account
Authors:   NRU MPEI, Zarudskiy Georgy K.
Published: March 2022

A technique has been developed to minimize active power losses that takes into account the corona effect on extra-high voltage overhead power transmission lines in normal modes of their operation. The corona effect is modeled by a specific conductivity, which is a nonlinear function of the voltage level. The equivalent conductivity value is corrected for the actual weather conditions iteratively by changing the r.m.s. voltage value. A universal expression for estimating the effect of operating parameters on the change of voltage along the line length and a graphic illustration of this effect are presented. By differentiating the functional dependence of the total active power losses, formulas are obtained for calculating the operating parameters corresponding to the minimum loss values, assuming that the conductivity does not depend on voltage. It is shown that the operating and technical limitations on the voltage values at the line ends and in its intermediate sections significantly reduce the range of transmitted power with minimal losses. The iterative calculation sequence for determining the reduced voltage level corresponding to the lowest total losses is outlined. The transmitted power values at different corona intensities are calculated. The study results have shown the need to take into account the nonlinear dependence of equivalent conductivity on the r.m.s. voltage value.
Technical Solutions to Detect Overheating of 0.4–10 kV Switchgear Components
Authors:   PJSC of Power Engineering and Electrification ", OHLOPKOV Andrey V. ,   Mosenergo", SIGITOV Oleg Yu. ,   PJSC of Power Engineering and Electrification "Mosenergo", BITNEY Vladislav D. ,   PJSC of Power Engineering and Electrification "Mosenergo", LAPUKHIN Sergey N. ,   PJSC of Power Engineering and Electrification "Mosenergo", KUNITSKIY Andrey G. ,   PJSC of Power Engineering and Electrification "Mosenergo"
Published: March 2022

The article addresses matters concerned with safe monitoring of the electrical equipment technical condition and transfer of the majority of electrical installations operated by PJSC Mosenergo to the category of low-maintenance ones. A comparative analysis of technologies for automatically monitoring the heating of contact connections, including radio-channel, pyrometric and gas-analytical automatic overheating detection systems (AODS) is carried out. It has been shown that gas-analytical systems have both technical and economic advantages, which makes them a preferred choice when equipping 0.4–10 kV switchgears with systems for automatically detecting the overheating of contact connections. Criteria for selection of existing electrical installations recommended for being fitted with AODS have been developed. Technical requirements for automatic overheating detection systems of 0.4–10 kV switchgear components have been determined, and technical solutions have been developed for their application at PJSC Mosenergo facilities and for setting up automated monitoring of the technical condition of 0.4–10 kV switchgear components and transmission of data on the revealed defects to control centers. It has been planned to put the developed gas-analytical automatic overheating detection system in pilot operation at existing electrical installations of PJSC Mosenergo’s CHPP-12 branch.
Identifying Critical Success Factors for Effective Development of E-monitoring
Authors: Shahoozadeh Sadegh
Published: March 2022

Electronic government has been among certain concepts and strategies facilitating public management in most societies. Thus, being concerned about the said concept and making its infrastructure thought operational have always been of great interest. Methodology: The essential part and the most important pyramid of e-government have been devoted to e-monitoring. Essentially, such kind of supervision has been made toward the general idea of the e-government and includes the most important means for the materialization of its goals accordingly. This research has been conducted aiming at identifying key factors, which influence effective development of e-supervision in four structural, technical, strategic and human dimensions. The statistical population of this research includes all experts from State General Inspection Organization (Khorasan Razavi, South Khorasan, North Khorasan, Golestan, and Sistan Va Baluchestan Provinces) consisting of 110 persons; the entire persons have been chosen as sample going through statistical method. Data collection means of this research is a questionnaire consisting of 40 measurements, classified on the basis of the Likert Scale. Results: Collected data by the said questionnaire has been processed using the Spss method. Chi-Squared and Friedman’s Test has been used for the analysis of data. According to the rating of the said four dimensions, technical dimension has been the most effective one in effective development of e-monitoring and structural, strategic and human dimensions stand next. Conclusion: The research results indicate that all dimensions, subject of study, are effective on the effective development of e-supervision. In concluding, certain guidelines have been presented for the effective development of e-monitoring accordingly.
The Impact of Voluntary Disclosure of Intellectual Capital on the Stock Return in Listed Companies of Tehran Stock Exchange
Authors: Ghasemi Ali , Rostami Vahab , Ghorbani Behzad
Published: March 2022

In this Study, the effect of voluntary disclosure of Intellectual capital information on the stock return of the listed companies in Tehran Stock Exchange will be discussed. A dummy variable was defined and the required items for intellectual disclosure were designed. By referring to the financial statements and reports of the board of directors wanted data for companies were collected.  Data analysis included multiple regressions using panel data and fixed effects. Methodology: Then, by assessing the items in the board directors’ report, number 1 was assigned to the items evident and zero to those forgone. In the end, a score for each company was determined to expose the intellectual capital disclosure. 137 companies were selected by systematic samplings for a period of 5 years (2010-2014) and appropriate statistical tests were applied. Results: The results showed that voluntary disclosure of intellectual capital has a positive and significant impact on the stock return of those companies. This result is in compliance with the past finding. Conclusion: in this study, the positive effect of these intangible assets on the return on equity was observed. Based on the results, the professional accounting bodies are recommended to develop standards and mechanisms for continuous disclosure in the notes to the financial statements disclose information.
An Investigation of Effectiveness of Agriculture Sector Development Fund of Yazd Province on Shareholder Associations from Perspective of Shareholders
Authors: Farashah Davud Dehghanpur , Salem Jalal , Islami Mohamadreza
Published: March 2022

According to Iranian government’s politics to support agriculture sector and by considering this that it is required to have capital of private sector along with the capital of public capital in this sector, the government has initiated to establish funds to support agriculture sector development on national, product, province, town and rural and tribal women levels. This survey-descriptive research aims to investigate the effectiveness of the Agriculture Sector Development Fund of Yazd Province on shareholder associations in perspective of shareholders. Methodology: Statistical population of this study includes shareholders of Agriculture Sector Development Fund of Yazd Province that were 226 persons. 110 samples were selected by the simple random method using Cochran’s formula. To analyze data, descriptive and analytical statistics were utilized. Results: After analyzing by SPSS software, findings indicated that there is a positive and meaningful relationship between variables of effectiveness scope of covered companies including improvement of position, employment, income, development of activities of shareholders, development of agriculture activities with the effectiveness of this fund. Conclusion: Making payment facilities purposeful in advantageous fields of the province such as greenhouse and also models of serving patterns and formation of production chains are some approaches.
Providing a structured approach for evaluating and selecting suppliers in a supply chain
Authors: Goli A , Ahmadi S.A. , Azadani M. Nasr , Rezaei H.
Published: March 2022

Supply chain management (SCM) is one of the important competitive strategies used by modern organizations. The main objective of supply chain management is to integrate various suppliers in order to satisfy market demand.  Selecting and evaluating suppliers plays an important role in creating a supply chain. The old method of selecting and evaluating suppliers is focused on the needs of businesses and considering it for the entire supply chain of an organization fails to work. So this study presents a structured approach for selecting and evaluating suppliers based on the integrated supply chain structure. For establishing a procedure for the selection and evaluation of suppliers in the supply chain, first, the competitive strategy of the organization by analyzing the strengths, weaknesses, opportunities, and threats (SWOT) is specified. Based on competitive strategy, supplier selection criteria and indicators in order to establish a framework for selecting suppliers are elected. Subsequently, potential suppliers through Data Envelopment Analysis (DEA) are monitored. Finally, the techniques of Multi-Criteria Decision Making (MCDM) is used to rank suppliers. In this paper, a structured approach to select suppliers in an industry will be examined.
New approaches for solving the old problem
Authors: Khachatryan L. A. , Shcherbakov А. P. , Chikvina I. I. , Nikolaeva D. M.
Published: March 2022

Infantile hemangioma (IH) is a benign vascular tumor with abnormal proliferation of endothelial cells and impaired vascular architecture. It is believed that the pathogenesis of IH is based on angiogenesis impairment caused by imbalance between angiogenic and anti-angiogenic factors. Despite spontaneous regression, which is observed in 90% of cases of IH, several tumor localizations may indicate the possibility of systemic manifestations or lead to the development of complications that require medical interventions. Here we report 2 cases of the most frequent and severe complications of IH and the first successful use of combined treatment strategy including metronomic chemotherapy (cyclophosphamide plus vinblastine) and nonselective b-blocker (propranolol) in IH. The parents of the patients agreed to use the information, including the photographs of children, in scientific research and publications. In contrast to glucocorticoids commonly used in clinical practice for complicated forms of IH, metronomic chemotherapy showed high efficacy and safety. It led to a rapid, within the first two weeks, clinical improvement resulting not only in stopping tumor growth, but even in size reduction. Such a rapid response to therapy allowed to stop the development of ulcers and necrosis with secondary infection, and to prevent severe vital complications of IH such as the upper respiratory tract compression.
A case of medulloblastoma in a patient with hereditary angioedema with C1 inhibitor deficiency
Authors: Viktorova E. A. , Salnikova E. A. , Papusha L. I. , Shchukin V. V. , Nechesnyuk A. V. , Gornostaev V. V. , Kuzmenko N. B.
Published: March 2022

Hereditary angioedema (HAE) is a disease characterized by edema of various localizations. Though classified as primary immunodeficiencz the disease lacks manifestations characteristic for primary/secondary immunodeficiencies. Medulloblastoma is one of the most frequent central nervous system tumors in children. The presence of a hereditary orphan disease (HAE) does not contradict the development of oncological process of any localization. The combination of two different diseases in a particular patient requires special approaches to the treatment of each of them. In this article we describe a clinical case of medulloblastoma in a patient with HAE. We also describe our approach to preventive therapy in a patient with a genetically confirmed HAE with C1 inhibitor deficiency before the manifestation of clinical symptoms which was implemented in order to apply program complex therapy of medulloblastoma in his entirety, including surgical procedures and radiation therapy, under general anesthesia. The patient’s parents gave consent to the use of their child's data, including photographs, for research purposes and in publications.
The outcomes of children with acute myeloid leukemia treated in accordance with the AML–MM-2006 protocol
Authors: Kalinina I. I. , Venyov D. A. , Olshanskaya Yu. V. , Sadovskaya M. N. , Goronkova O. V. , Salimova T. Yu. , Petrova U. N. , Baidildina D. D. , Suntsova E. V. , Evseev D. A. , Matveev V. E. , Antonova K. S. , Khamin I. G. , Dubrovina M. Е. , Zerkalenkova E. A. , Gaskova M. V. , Popov A. M. , Kashpor S. A. , Mandzhieva A. I. , Konyukhova T. V. , Khachatryan L. A. , Litvinov D. V. , Balashov D. N. , Shelikhova L. N. , Maschan M. A. , Novichkova G. A. , Maschan A. A.
Published: March 2022

Over the past years, the outcomes of patients with acute myeloid leukemia (AML) have significantly improved due to the use of intensive chemotherapy, more effective supportive therapy, and the availability of allogeneic hematopoietic stem cell transplantation. This article presents the outcomes of children with AML treated in accordance with the AML-MM-2006 protocol. Our study was approved by the Independent Ethics Committee of the Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology. The study included 233 patients with a median age of 6.5 years (7 days – 18 years) who were stratified into the following risk groups: standard risk, intermediate risk, and high risk. The 5-year event-free survival (EFS) was 0.64 ± 0,14, 0.49 ± 0.05, and 0.43 ± 0.05 for standard-risk (n = 12), intermediate-risk (n = 106), and high-risk (n = 115) patients, respectively (p = 0.14), while the 5-year overall survival (OS) was 1.0 year, 0.7 ± 0.05 and 0.55 ± 0.05, respectively (p = 0.001). The OS in the entire cohort was 0.68 ± 0.032. Factors associated with poor prognosis included hyperleukocytosis, the presence of extramedullary lesions, and age < 1 year. The overall survival rates in these patient groups were 0.55 ± 0.08, 0.39 ± 0.09 and 0.49 ± 0.08, respectively. The worst prognosis was for patients with monosomy 7 and t(7;12) whose OS rates were 0.25 ± 0.2 and 0.4 ± 0.2, respectively. For non-responders and patients with relapsed AML, the OS was 0.33 ± 0.08 and 0.54 ± 0.06, respectively. Early death (before remission could be achieved) occurred in 4% of patients, and 3.8% of patients died in first remission. Sixtytwo percent of deceased patients died of disease progression. In the entire cohort of patients, the five-year EFS was 0.53 ± 0.047, the cumulative risk of relapse after 3 years of remission was 40%, the confidence interval was 23–89%.
Hodgkin's lymphoma in children and adolescents in Belarus Republic: 23-year survival rate of 606 pediatric patients
Authors: Markavets A. F. , Bydanov O. I. , Kisialeu L. P.
Published: March 2022

The article presents an analysis of treatment outcomes of pediatric patients with classical Hodgkin's lymphoma (HL) in the Republic of Belarus over more than a 20-year period. Patients aged 0 to 18 years with HL received therapy according to the DALHD-90(m) protocol. Therapy modifications involved the use of systemic chemotherapy according to the OPPA regimen (vincristine, procarbazine, prednisone and doxorubicin) for patients of both sexes and dose-reduced involved-field radiotherapy (20 Gy) for patients with early or intermediate stage HL. The aim of our study was to analyze the survival and clinical characteristics of pediatric patients with HL. The study was approved by the Independent Ethics Committee and the Scientific Council of Belarusian Research Center for Pediatric Oncology, Hematology and Immunology of the Ministry of Health of the Republic of Belarus. The analysis included 606 patients with HL, who had received treatment at the Belarusian Research Center for Pediatric Oncology, Hematology and Immunology from January 1, 1998 until December 31, 2020. The median age was 15.3 years. At 23 years, the event-free survival of the study patients was 85 ± 2%, the overall survival was 93 ± 1%, and the cumulative recurrence rate was 10 ± 1.3%. The long-term treatment results of pediatric patients with HL in the Republic of Belarus indicate that the protocol therapy is highly effective and can achieve outcomes that are equivalent to those in countries with a developed healthcare system. The applied therapeutic strategy demonstrates clinical efficacy in stage I–III HL. About 15% of patients with advanced HL (stage IV) constitute the main target group for which a search for new treatment approaches improving treatment outcomes is required.