bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS LUAS PENGELOLAAN WILAYAH LAUT JAWA TENGAH PADA BEBERAPA SISTEM PROYEKSI DAN SISTEM KOORDINAT
Authors: Awaluddin Moehammad , Ammarohman Fauzi Janu , Nugraha Arief Laila , Sasmito Bandi , Azizah Khofifatul
Published: September 2022

Permendagri No. 141 tahun 2017 menyebutkan bahwa Peta Batas Daerah termasuk Peta Batas Pengelolaan Wilayah Laut menggunakan sistem proyeksi Transverse Mercator dan sistem koordinat UTM. Sistem proyeksi ini bersifat konform yang mempertahankan bentuk (sudut) tetapi tidak mempertahankan luas dan jarak. Penelitian ini menghitung perbedaan luas pada beberapa sistem proyeksi dan sistem koordinat di batas pengelolaan wilayah laut Provinsi Jawa Tengah. Sistem proyeksi dan sistem koordinat yang digunakan adalah: Proyeksi Lambert Silinder Equal Area, Proyeksi UTM Zona 49 Selatan, Proyeksi Transverse Mercator dan Proyeksi Mercator dengan dua sistem koordinat yang berbeda. Selisih luas dihitung terhadap luas hasil proyeksi Lambert Silinder Equal Area yang mempertahankan luas pada sistem proyeksinya. Luas daerah pengelolaan wilayah laut Provinsi Jawa Tengah pada proyeksi UTM dan Transverse Mercator mempunyai persentasi selisih luas yang kecil jika dibandingkan dengan luas proyeksi Lambert Silinder Equal Area. Besarnya persentase selisih luas tidak signifikan sehingga penarikan batas pengelolaan wilayah laut Provinsi Jawa Tengah dapat dilakukan pada sistem proyeksi konform UTM. Perbedaan persentasi luas yang besar pada proyeksi Mercator dibandingkan dengan proyeksi UTM dan Transverse Mercator disebabkan letak daerah yang berjarak paling jauh pada garis yang mempunyai distorsi nol.Permendagri No. 141 of 2017 states that the regional boundary map including the maritime area management boundary map uses the Transverse Mercator projection system and the UTM coordinate system. This projection system is conform projection which maintains shape (angle) but does not maintain area and distance. This study calculates the area differences in several projection systems and coordinate in the management boundaries of the sea territory of The Central Java Province. The projection system and coordinate system used are: Equal Area Cylindrical Lambert Projection, UTM Projection zone 49 south, Transverse Mercator Projection and Mercator Projection with two different coordinate systems. The difference in area is calculated against the projected area of the Lambert Cylindrical Equal Area which maintains the area of the projection system. The area of the sea management area of Central Java Province in the UTM and Transverse Mercator projections has a small percentage difference in area when compared to the projected area of the Lambert Cylindrical Equal Area. The magnitude of the percentage difference in area is not significant so that the drawing of boundaries for the management of the sea area of Central Java Province can be carried out on the UTM conforming projection system. The bigger percentage of area difference of the Mercator projection compared to the UTM and Transverse Mercator projections is due to the location of the area that is the farthest away from the line which has zero distortion.
Evaluation of the effect of Castanea sativa extracts on lipoxygenase activity
Authors: Al-lehebe Nashwan Ibrahem , Hameed Hamza Namiq , Al-sadoon Mohammed Bahry
Published: September 2022

Lipoxygenase LOX is a lipolysis enzyme that oxidises unsaturated fatty acids like arachidonic and linoleic acids to form unhealthy chemicals such as dienes, leukotrienes and malondialdehyde in advanced oxidation, which is harmful to cells. In this study, the polyphenols and saponins compounds were extracted from Castanea sativa using Soxhlet for 3 days. Colourimetric and HPLC techniques were used to identify polyphenols and saponins in the extracts respectively. The effects of these extracts were evaluated on LOX activity, which was purified from the liver of Iraqi Cows (AL-Sharabi Cows) as well as on E. coli and Pseudomonas bacteria resistance. According to the LOX purification procedures, the specific activity increased from 0.001 to 0.03 U/mg with a purification fold of 30 times and a yield percentage of 174. Gallic acid 7.72 mg, Rutin 29.25 mg, Quercetin 27.6 mg, kaempferol 34.42 mg, Apigenin 5.25 mg and Catechin 25.8 mg/100 gm of Castanea fruit was obtained. The inhibitory effect of polyphenol and saponin extracts on LOX activity was at 100 and 40 µg respectively. Line weaver-Burk plot was used to investigate the type of inhibition that was found non-competitive. However, these extracts were studied at concentrations of 500, 250 and 125 µg on bacteria resistance. Polyphenols had the best effect at 500 and 125 µg on E. coli and Pseudomonas bacteria respectively. Whereas, saponin had the best effect at 250 and 125 µg for E. coli and 125 µg for Pseudomonas.
Acute effects of euglycemic‐hyperinsulinemia on myocardial contractility in male mice
Authors: Tadinada Satya Murthy , Grzesik Wojciech J. , Kutschke William , Weiss Robert M. , Abel E. Dale
Published: September 2022

Type 2 diabetes and obesity are associated with increased risk of cardiovascular disease, including heart failure. A hallmark of these dysmetabolic states is hyperinsulinemia and decreased cardiac reserve. However, the direct effects of hyperinsulinemia on myocardial function are incompletely understood. In this study, using invasive hemodynamics in mice, we studied the effects of short‐term euglycemic hyperinsulinemia on basal myocardial function and subsequent responses of the myocardium to β‐adrenergic stimulation. We found that cardiac function as measured by left ventricular (LV) invasive hemodynamics is not influenced by acute exposure to hyperinsulinemia, induced by an intravenous insulin injection with concurrent inotropic stimulation induced by β‐adrenergic stimulation secondary to isoproterenol administration. When animals were exposed to 120‐min of hyperinsulinemia by euglycemic‐hyperinsulinemic clamps, there was a significant decrease in LV developed pressure, perhaps secondary to the systemic vasodilatory effects of insulin. Despite the baseline reduction, the contractile response to β‐adrenergic stimulation remained intact in animals subject to euglycemic hyperinsulinemic clamps. β‐adrenergic activation of phospholamban phosphorylation was not impaired by hyperinsulinemia. These results suggest that short‐term hyperinsulinemia does not impair cardiac inotropic response to β‐adrenergic stimulation in vivo.
Viscosity method for random homogenization of fully nonlinear elliptic equations with highly oscillating obstacles
Authors: Lee Ki-Ahm , Lee Se-Chan
Published: September 2022

In this article, we establish a viscosity method for random homogenization of an obstacle problem with nondivergence structure. We study the asymptotic behavior of the viscosity solution

u

ε

{u}_{\varepsilon }

of fully nonlinear equations in a perforated domain with the stationary ergodic condition. By capturing the behavior of the homogeneous solution, analyzing the characters of the corresponding obstacle problem, and finding the capacity-like quantity through the construction of appropriate barriers, we prove that the limit profile

u

u

of

u

ε

{u}_{\varepsilon }

satisfies a homogenized equation without obstacles.
Die Entwicklung von Qalamos – das neue Portal für Handschriften aus asiatischen und afrikanischen Schrifttraditionen
Authors: Schmid Larissa
Published: September 2022

Im Juni 2022 startete Qalamos, das neue Portal für Handschriften aus asiatischen und afrikanischen Schrifttraditionen. Erstmalig sind nun die Metadaten und Digitalisate von orientalischen Handschriften aus mehr als 20 deutschen Institutionen in einem gemeinsamen Portal zugänglich. Im Beitrag wird das Forschungsprojekt „Orient-Digital“ vorgestellt und der Entwicklungsprozess des Portals unter Einbezug von Nutzenden dargestellt.
Forschungsdatenmanagement im Verbund weiterentwickeln – ein Einblick in das Projekt FDNext
Authors: Augsten Marie Theres , Fischer Patryk , Kienbaum Janna , Lehmann Anna , Paßmann Sven , Schmiederer Simon
Published: September 2022

Im DFG-Forschungsprojekt FDNext arbeiten sechs Universitäten aus Berlin und Brandenburg zusammen, um im Verbund ein nachhaltiges institutionelles Forschungsdatenmanagement mit der Entwicklung verschiedener Tools für Fachbereiche, Rechtsberatung, Policies und Service Management auszubauen. In der dreijährigen Förderphase werden Werkzeuge und Konzepte für Fachbereiche, Rechtsberatung, Policies und Service-Management im engen Austausch mit Projektpartner*innen aus Fakultäten, Fachbereichen und der Forschung erarbeitet, (weiter-)entwickelt und abschließend mit Akteur*innen der bundesweiten FDM-Community evaluiert. In dem Artikel werden die sechs Arbeitsschwerpunkte und ihre Zwischenergebnisse nach Ablauf der ersten Hälfte der Projektlaufzeit vorgestellt.
Ein Bibliotheksbrand und ein Raubzug durch Europa
Authors: Trzaska Lisa
Published: September 2022

Während des Zweiten Weltkriegs erworbene Bestände in der Bibliothek des Botanischen Gartens Berlin werden in einem aktuellen Projekt auf NS-Raubgut untersucht. Der Artikel erläutert, wie nach dem Verlust der Bibliothek durch einen Bombentreffer 1943 unmittelbar große Mengen botanischer Fachliteratur als Ersatz beschafft werden konnten, die teils mit Raubgut durchsetzt sind. Dabei geraten nicht nur die am Raub beteiligten staatlichen und politischen Institutionen in den Blick, sondern mehr und mehr auch der antiquarische Buchmarkt in der NS-Zeit.
Progressiver Konservatismus oder die Ethik der Öffentlichen Bibliothek
Authors: Kubíček Tomáš
Published: September 2022

Der Beitrag thematisiert die Schlüsselrollen von Öffentlichen Bibliotheken in Beziehung zu ihren diskutierten sozialen Rollen. Er macht sich Gedanken über das System von sozialen Institutionen und aus dieser Perspektive über die Rolle der Funktion und Identifikation der Bibliothek und ihrer Beziehung zu Gesellschaft. Er blickt kritisch auf die Erweiterung von Bibliotheksdiensten, welche nicht die primär soziale und systematische Funktion von Öffentlichen Bibliotheken berücksichtigen und daher einen negativen Einfluss auf das ganze System von öffentlichen Institutionen haben. Der analytische Teil des Beitrags beschäftigt sich mit dem Grund für die Entstehung von Öffentlichen Bibliotheken in der Tschechoslowakei nach 1918, der aktuell aufgenommenen Konzeption der Entfaltung von Bibliotheken in der Tschechischen Republik und der Erfahrung, die die Öffentlichen Bibliotheken während des sogenannten Lockdowns aufgrund der Pandemie 2020–2021 gemacht haben. Am Schluss macht sich der Autor Gedanken über die Identität und der gesellschaftlichen Verantwortung der Öffentlichen Bibliothek.
Genome-wide identification of MAPK family genes and their response to abiotic stresses in tea plant (Camellia sinensis)
Authors: Liu Xinhao , Zhao Min , Gu Caihua , Jiang Haodong , Sun Junyan , Li Jie
Published: September 2022

Mitogen-activated protein kinase (MAPK) cascades are conserved and universal signal transduction modules that play important roles in regulating stress responses in plants. Although MAP3K, MP2K, and MPK family in tea plant (Camellia sinensis) have been investigated, little is known about MPK family genes responding to various abiotic stresses in tea plant. In this study, we performed a comprehensive genome-wide analysis of the tea plant MAPKs (CsMPKs) family gene based on the genomic data of tea plants by bioinformatics-based methods. Here, 21 putative CsMPK genes were identified in the tea plant and divided into 4 subfamilies according to the homologous to Arabidopsis and their phylogenetic relationships. The gene structure and conserved motifs of these CsMPKs in the same group showed high similarity, suggesting that they were highly conserved and might have a similar function. The expression profiles of the CsMPK genes were further investigated by quantitative real-time reverse transcription PCR, indicating that many CsMPK genes were involved in response to cold, drought, heat, or heat combined with drought treatment, suggesting their potential roles in abiotic stress responses in tea plant. These results would provide valuable information for further exploring the functional characterization of CsMPK genes in tea plants.
Defining Migration Writing
Authors: Kosmalska Joanna
Published: September 2022

With a view to extending and enriching the vibrant, ongoing debate about migration and literature, this article makes an attempt to define »migration writing«. Using three perspectives – the theme-oriented, ethnic-oriented and text-oriented approaches – the paper examines the concept of »migration writing« in relation to other literary terms. Therefore, the starting point for the discussion is a brief comparison of migration writing with autobiography, travel writing and postcolonial literature. Then some useful comparisons are made to other related literary concepts, such as exile literature, refugee literature, foreigners’ literature, guest worker literature, Kanake literature, »allochthonous« literature, ethnic literature, minority literature, diasporic literature, hyphenated literature, multicultural literature, intercultural literature, émigré literature/emigrant literature, immigrant literature, migrant literature, the literature of migration. From these concepts, there emanates what I call »migration writing«.

The label is used by me as a term for a whole variety of different types of literary and non-literary texts that have been published since the 1990s. These texts either tackle the topic of migration or emerge from the experience of migration (but not necessarily address the subject of migration). It is also not necessary for the author to be a migrant: it is enough that his or her work is inspired or influenced by the experience of migration and is imbued with a vision of cosmopolitan, transnational, hybrid society and the globalised world. Given the large scope of this definition, it seems best to define the genre as a constellation of many different types of text which are connected to one another by a set of characteristic features. Some of these features include: the real-life nature of the writing, creolization and multilingualism in the text, references to multiple cultures and/or geographic locations, impact of the Internet and online communication on the structure of the work, common themes and motifs.

The article ends by illuminating the research potential of migration writing. Among other things, it gives highly informative accounts of migration experience, exposes the stereotypical representations of migrants, gives piercing insights into migrants’ host and home cultures, explores the issues of identity, nationality, borders and belonging, provides alternative knowledge about current social and cultural transformations. Acting as a counterweight to the dominant narratives, migration texts often make visible the phenomena that are unintentionally ignored or wilfully excluded from the mainstream public discourse. Consequently, they provide alternative knowledge that can be a useful research material in all kinds of areas, such as sociological, political, economic or culture studies.
Psychic consequences of infertility on couples: A short commentary
Authors: Ara Irfat , Maqbool Mudasir , Zehravi Mehrukh
Published: September 2022

Infertility is a reproductive system condition defined by the failure to carry a clinical pregnancy following a period of 12 months or more of unprotected regular intercourse. Despite the fact that infertility is not a life-threatening condition, it is still a stressful life event for couples or people owing to the high value placed on having a child by individuals or society in general. Infertile couples are dealing with a variety of emotional issues in addition to a medical ailment. Infertile couples’ emotions, feelings, and beliefs frequently alter as a result of their infertility diagnosis. Due to the extreme seclusion of the subject, infertile couples may resort to hiding the problem if they are under a lot of societal pressure. The inability to conceive has been regarded as a stressful situation for both the person and the couple. The news of infertility elicits the same emotional responses as a death or catastrophic sickness. The medical treatment of infertility causes anxiety and pain, and this suffering and anxiety can have an impact on the treatment’s outcomes. Failed attempts result in major narcissistic injuries, which are frequently compounded by sexuality issues and relationship difficulties.
Handlungsfähigkeit und systemische Gewalt: Weibliche Erotik und Macht am Beispiel der Mystikerin Andal
Authors: Poggendorf-Kakar Katharina
Published: September 2022

Ist emanzipatorisches Handeln von Frauen innerhalb einer religiös-patriarchalen Kultur möglich? Wird es gesucht? Es löst oft ein Unbehagen aus, wenn Frauen ihre Identität und Macht in anderen Kontexten verorten als in säkularen Vorstellungen von Begehren und Freiheit. Anhand der tamilischen Mystikerin Andal (9. Jh.) und Beispielen der gegenwärtigen hinduistischen Kultur wird Fragen nach Widerstand, Unterwerfung und systemischer Gewalt nachgegangen.
Avatar of Desire: Das Begehren des ganz Anderen als Einfühlungs-Erotik
Authors: Loew Léonard
Published: September 2022

Im Folgenden geht es um die erotische Komponente von Erkenntnis und Erkenntnisästhetik im Hinblick auf das Gewahr-Werden und Ergriffen-Sein des Gläubigen durch Gott. In diesem Sinne impliziert der Topos der Gotteserkenntnis auch eine körperlich fundierte Semantik, als Nähe zu Gott, die ein Verlangen nach (An-)Erkannt-Sein und Verstanden-Werden auf der einen Seite wie auch nach Gottes-Erkenntnis auf der anderen Seite beinhaltet. Das Begehren des Gläubigen nach einer Einfühlung in Gott (der seinerseits all-empathisch, also all-begehrend ist

Vgl. Loew 2021a; b.

) kann als der Versuch einer Herstellung von Beziehung und körperlicher wie geistiger Intimität, aber auch als mögliche Form der Überwältigung verstanden werden. Gottvater als elterliche Figur des Begehrens (Ödipus)

Vgl. Freud 1972.

, als unerreichbarer und zugleich geliebt-liebender Vater

Vgl. Bartholomäus 1982.

, bildet insofern immer den transzendenten Fixpunkt des Gläubigen und seiner Einfühlungs-Erotik. Dies soll theoretisch v.a. unter Rückgriff auf Freuds Libido-Theorie sowie Liebes- und Mimesis-Konzeptionen und empirisch durch die Auswertung mittelalterlicher Gotteserkenntnis-Diskurse aufgezeigt werden.
Was ist das eigentlich: Sexualität?
Authors: Rugenstein Kai
Published: September 2022

Ausgehend von einer historischen Verortung wird dargestellt, welchen spezifischen Beitrag die Psychoanalyse zum Verständnis dessen, was Sexualität ist, leisten kann. Dabei rückt eine andere, eine sprachlose (infantile) und noch nicht genital organisierte Form der Sexualität in den Blick, welche nicht biologisch-angeboren sondern intersubjektiv-erworben ist. Das die Psychoanalyse besonders interessierende unbewusste Sexuelle zentriert sich nicht um instinkthafte Bedürfnisse, sondern um triebhafte Wünsche. Hier ergibt sich eine überraschende Überschneidung mit der psychoanalytischen Auffassung von Religion, welche Freud als eine von infantilen Wünschen getriebene Illusion verstanden wissen wollte. Religion und Sexualität führen uns – bei allen offensichtlichen Unterschieden – beide vor das In-fantile, vor das Sprach-lose. Es wird diskutiert, inwieweit dies mit erwachsener Wortgewalt aus der Welt zu schaffen oder nicht vielmehr doch als ein eigenständiger Bereich zur Geltung zu bringen sei.
Der Glanz der Körper
Authors: Bieler Andrea
Published: September 2022

Christliche Sexualitätsdiskurse sind sowohl auf der Ebene der theologischen Reflexion als auch in der Artikulation religiöser Akteur*innen mehrheitlich Regel- bzw. Regulationsdiskurse. Die Frage nach dem, was erlaubt und was verboten ist, lässt dabei nur wenig Raum für ein differenziertes Sprechen über sexuelles Begehren, Wünsche und Erfahrungen. Vielmehr lässt sich in der Geschichte des Christentums ein Sprechen identifizieren, das sich im Spannungsfeld von religiöser Dämonisierung und Überhöhung bewegt. Dabei wird ein binär strukturiertes Diskursfeld produziert, in dem durch verschiedene religiös legitimierte Normalisierungspraktiken die Heterosexualität als exklusive Norm hervorgebracht wird. Auch wenn diese heteronormative Orientierung in liberalen Varianten des Christentums inzwischen abgelehnt wird, bleibt es eine Herausforderung, die Argumente kritisch zu analysieren. Vor diesem Hintergrund werden biblisch-hermeneutische Vermittlungsversuche sowie ethische Kriterienbildung reflektiert. Abschließend wird für die Entwicklung einer vertieften Ambiguitätstoleranz plädiert.
Warum es „Sexualität im Islam“ nicht gibt
Authors: Ghandour Ali
Published: September 2022

Der Artikel versteht sich als kritische Aufarbeitung essentialistischer Vorstellungen über das Muslimentum am Beispiel der Diskussionen um Sexualität und Gender, mit besonderem Augenmerk auf die derartigen essentialistischen Ansätzen eigenen Probleme. Da für diese Auseinandersetzung mit dem Essentialismus eine vor mir vorgeschlagene Differenzierung zwischen drei Begriffen, nämlich zwischen islām (kleingeschrieben), Islam (großgeschrieben) und Muslimentum, eine fundamentale Rolle spielt, steht am Beginn eine Definition dieser Begriffe. Daran anschließend wendet sich der Beitrag drei Formen des Essentialismus zu (wobei ich auch die dritte Form, die eigentlich als Reaktion auf den abstrakten Essentialismus entstanden ist und „den Islam“ als Diskurs begreift, als eine Spielart des Essentialismus betrachte, weil sie viele für diesen charakteristische Züge annimmt). Am Beispiel der muslimischen LGBTQQIA (lesbische, schwule, bisexuelle, transsexuelle, queere, questioning, intersexuelle und asexuelle Menschen) sollen dann im letzten Punkt die methodischen Schwierigkeiten, die mit den erörterten Ansätzen einhergehen, veranschaulicht werden.
The use of animal classifiers as a stance negotiation strategy in Cantonese interactional discourse
Authors: Chan Ariel
Published: September 2022

This study adopts the idea of ‘stance triangle’ and ‘double dialogicality’ and examines the use of animal classifiers for human referents in the stance negotiation process in Cantonese. Drawing on the data from a Corpus of Mid-twentieth-century Hong Kong Cantonese, this study explores how participants deploy two animal classifiers (i.e., tiu4, a classifier forfish, andzek3, a classifier foranimal) to express their negative stance towards another person. The present study specifically analyzes three examples where the relationships between the stance subjects (SS1-SSn) and stance objects (O) are different: O is present in the interaction in one instance, and absent in the other two instances. My analysis suggests that upon the display of negative stance towards O by the original stance subject, other stance subjects can deny the ‘joint attention’ to avoid establishing any alignment link with the original stance taker as a way of negotiating their stance. I propose an extended model of ‘stance triangle’ which better captures the fluidity and dialogicality in the stance negotiation process.
Modeling and simulation of CZTS based solar cells with ZnS buffer layer and ZnO:F as a window layer using SCAPS-1D
Authors:   LNCSM, Department of physics, ENSKouba, Alger, Algeria, Yassine B. , Tahar B. ,   LNCSM, Department of physics, ENSKouba, Alger, Algeria, Fathi G. ,   LNCSM, Department of physics, ENSKouba, Alger, Algeria
Published: September 2022

ZnS is an excellent candidate for the substitution of the CdS buffer layer inCZTS based solar cells, is nontoxic and is relatively less costly.It has been shown that a surface composition adaptation is favorable for the replacement of the buffer layer CdS by ZnS so as to obtain an interface quality with the CZTS layer that makes it possible to control the diffusion phenomenon of faults to this interface. SCAPS-1Dsoftware is used to simulate CZTS/ZnS/ZnO:F thin-film solar cell where the key parts are p-CZTS absorber layer and n-ZnS buffer layer.
Cellular specificity of androgen receptor, coregulators, and pioneer factors in prostate cancer
Authors: Leach Damien A , Fernandes Rayzel C , Bevan Charlotte L
Published: September 2022

Androgen signalling, through the transcription factor androgen receptor (AR), is vital to all stages of prostate development and most prostate cancer progression. AR signalling controls differentiation, morphogenesis, and function of the prostate. It also drives proliferation and survival in prostate cancer cells as the tumour progresses; given this importance, it is the main therapeutic target for disseminated disease. AR is also essential in the surrounding stroma, for the embryonic development of the prostate and controlling epithelial glandular development. Stromal AR is also important in cancer initiation, regulating paracrine factors that excite cancer cell proliferation, but lower stromal AR expression correlates with shorter time to progression/worse outcomes. The profile of AR target genes is different between benign and cancerous epithelial cells, between castrate-resistant prostate cancer cells and treatment-naïve cancer cells, between metastatic and primary cancer cells, and between epithelial cells and fibroblasts. This is also true of AR DNA-binding profiles. Potentially regulating the cellular specificity of AR binding and action are pioneer factors and coregulators, which control and influence the ability of AR to bind to chromatin and regulate gene expression. The expression of these factors differs between benign and cancerous cells, as well as throughout disease progression. The expression profile is also different between fibroblast and mesenchymal cell types. The functional importance of coregulators and pioneer factors in androgen signalling makes them attractive therapeutic targets, but given the contextual expression of these factors, it is essential to understand their roles in different cancerous and cell-lineage states.
ACTIVE REPENTANCEIN TERMS OF THE OFFENCE OF TAX EVASION
Authors: ŞİŞMAN Gülden , SARSIKOĞLU Şenel
Published: September 2022

With the Law No. 7394 on the Amendments of Treasury-Owned Immovable Property Valuation and the Value Added Tax Law and Article 4 of the Law No. 375 on the Amendments of Certain Other Laws and Decrees and with the paragraphs added to Article 359 of the Tax Procedure Law with the characterization of remission, a new state of active repentance has been prescribed apart from the repentance and amendment institution regulated in Article 371 of the Tax Procedure Law. To take advantage of active repentance , the loss of tax arising from the acts caused by the offence of smuggling, the assessed tax, the late fee and interest must be paid within a certain period of time. Also, administrative proceedings regarding the imposition and assessment of tax penalties must not be sued, and if a suit has been filed, it should be waived. There will be reduced sentence for taxpayers who commit an offense but regret it, as well as the damage suffered by the treasury will be eliminated. There will be reduced sentences for taxpayers who commit an offense but regret it, as well as the damage suffered by the treasury will be eliminated.
Die neue Vertikal-Gruppenfreistellungsverordnung (EU) 2022/720 nebst Vertikal-Leitlinien – Kontinuität und Umbruch in der Vertriebspraxis
Authors: Wegner Anne C. , Schwenker Benjamin , Altdorf Samira
Published: September 2022

Nachdem die Vertikal-Gruppenfreistellungsverordnung 330/2010 (i. F. VGVO 2010) und die dazugehörigen Leitlinien (i. F. V-LL 2010) seinerzeit nur wenige Änderungen zu ihren Vorgängerversionen aufwiesen, stellen die Vertikal-Gruppenfreistellungsverordnung 2022/720 (i. F. Vertikal-GVO) sowie die diesbezüglichen Leitlinien (i. F. Leitlinien) eine tiefgreifendere Reform dar. Zwar haben die Leitlinien massiv an Umfang zugenommen, allerdings ist die Verordnung insgesamt praxisnäher geworden und gibt klarere Hinweise für eine Vielzahl von Einzelproblemen in Handels- und Liefervereinbarungen. Der Beitrag soll wichtige Änderungen im Lichte der Gesetzgebungshistorie aufzeigen und einordnen.
Clinical-endocrinological and echografical aspects of good-quality dysplasia of mammary glands at women of reproductive age
Authors:   Shupyk National Medical Academy of Postgraduate Education of MH of Ukraine, Kiev, Gladenko S.E. , Dovgan A.A. ,   Shupyk National Medical Academy of Postgraduate Education of MH of Ukraine, Kiev
Published: September 2022

The objective: to study modern clinical-endocrinologic and echografical aspects of good-quality dysplasia of mammary glands at women of reproductive age. Materials and methods. Were surveyed 90 patients aged from 22 till 45 years which are divided into 3 groups on 30 women: 1 group - group of control - the woman without pathology in mammary glands. The 2nd group included patients with diffuse form of good-quality dysplasia of mammary glands. The 3rd group was made by patients with a nodal form of a good-quality dysplasia of mammary glands. The complex the researches included clinical, echografical, endocrinologic and statistical methods. Results. Results of the conducted researches testify that it is possible to refer existence of chronic extragenital diseases, smoking, an early menarche to risk factors of development of a good-quality dysplasia of mammary glands, disturbances of a menstrual cycle, hysteromyoma and an adenomyosis, an artificial or spontaneous abortion. Disturbance of ratio of LG/FSG is characteristic for all patients with diseases of mammary glands. For these patients as the hypoprogesteronemia is characteristic. Disturbance of ratio of levels of Gonadotropinums in combination with hypoprogesteronomia can be referred to risk factors of development of good-quality dysplasia of mammary glands. Conclusion. The received results needs to be considered when developing algorithm of diagnostic and treatment-and-prophylactic actions. Key words: good-quality dysplasia of mammary glands, clinic, endocrinology, echography.
Tactics of surgical treatment of congenital spinal deformities in children
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Levytskyi A.F. , Burianov O.A. ,   Bogomolets National Medical University, Kyiv, Ukraine, Benzar I.M. ,   Bogomolets National Medical University, Kyiv, Ukraine,, Omelchenko T.M. ,   Bogomolets National Medical University, Kyiv, Ukraine, Ovdii M.O. ,   Bogomolets National Medical University, Kyiv, Ukraine,   Consultative and Diagnostic Polyclinic of the University Clinic of the Bogomolets National Medical University, Kyiv, Ukraine
Published: September 2022

Progress in spinal surgery during the second half of the twentieth century was made possible by a deeper study of the three-dimensional nature of the normal and pathological architecture of the spine. The problem of complex spinal deformities remains one of the most important in clinical vertebrology. In Ukraine, more than 9,000 children need surgery for scoliosis spinal deformities. Of these, more than 15% of children have congenital scoliosis deformities. Purpose - to conduct a retrospective analysis of the results of surgical treatment of congenital spinal deformities in children. Materials and methods. A retrospective analysis of the results of treatment of 36 patients (from 9 to 12 years) with congenital spinal deformities who received treatment at the Department of Pediatric Surgery of the Bogomolets National Medical University (National Children's Specialized Hospital «OHMATDYT», Kyiv) in the period from 2008 to 2018. Patients were divided into two groups: I (staged treatment) - 18 children who received treatment using halo-gravity traction (HGT), followed by spinal instrumentation; II (one-time treatment) - 18 children who underwent surgical correction with osteotomies (4-6 levels according to Ponte, VCR osteotomy at 1-2 levels). Results. Two groups of patients were studied. According to HGT, the main arc deformation improved to 55±25%. HGT - complications were observed in 12% (transient neurological disorders). In patients who underwent spinal instrumentation without prior traction complications were observed in 37% of patients (neurological transient disorders in the form of spinal cord dysfunction). In children with congenital spinal deformities, simultaneous implantation of the structure in comparison with staged treatment with HGT increases the risk of neurological deficits by 25%, HGT allows greater correction and adapt the spinal cord to further correction. Conclusions. In the surgical treatment of congenital spinal deformities, HGT reduces the risk of neurological complications, reduces the time of surgery and the amount of blood loss, allows us to get better results of correction. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of all participating institutions. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the authors. Keywords: halo-gravitational traction, scoliotic deformation, surgical treatment.
EN PRENSA Efecto de la suplementación de Selenio en algunos atributos y contenido de minerales esenciales en la semilla de frijol (Phaseolus vulgaris L.) EN PRENSA
Authors: Azpilcueta-Pérez Ma. Elizabeth , Pedroza Sandoval Aurelio , Sánchez-Cohen Ignacio , Trejo-Calzada Ricardo , Jacobo-Salcedo María del Rosario
Published: September 2022

El objetivo de este estudio fue evaluar el efecto del Selenio en las características morfológicas, físicas, peso y contenido de minerales esenciales en la semilla del frijol (Phaseolus vulgaris L.). Se usó un diseño experimental en bloques completos al azar con siete repeticiones. Los tratamientos fueron tres formulaciones químicas de Selenio: selenito de sodio (Na2SeO3), dióxido de selenio (SeO2) y selenato de sodio (Na2SeO4) a tres concentraciones cada una: 5,10 y 20 mg L-1 más el testigo (sólo agua des-ionizada). La aplicación de 10 mg L-1 de Na2SeO3 mejoró la anchura y longitud del grano, con valores de 7.22 y 12.68 mm, respectivamente y la aplicación de 5 y 20 mg L-1 de SeO2, mejoró el espesor y diámetro del grano, con valores de 7.68 y 5.09 mm, respectivamente. Consecuentemente, el peso de 100 semillas, fue significativamente mayor cuando se suplementó 5 mg L-1 de Na2SeO3 o SeO2, con valores de 30 y 30.99 g, respectivamente. Las formulaciones Na2SeO3 y SeO2 a concentraciones de 5 mg L-1, mejoraron el radio aspecto, volumen y área superficial del grano. Finalmente, la aplicación de SeO2 y Na2SeO3 a concentraciones de 10 y 20 mg L-1,aumentaron moderadamente el contenido de Ca y Cu, respectivamente. Las formulaciones Na2SeO3 y SeO2 a dosis entre 5 a 20 mg L-1 fueron los más consistentes en mostrar un mejor efecto en mejorar los atributos dela semilla de frijol, respecto a la formulación Na2SeO4 en cualquiera de las formulaciones usadas en este estudio.
Modern aspects of diagnosis and treatment of patients with spontaneous coronary artery dissection
Authors: Zainobidinov Sh. Sh. , Khelimsky D. A. , Baranov A. A. , Badoyan A. G. , Krestyaninov O. V.
Published: September 2022

Spontaneous coronary artery dissection (SCAD) is one of the rarest causes of acute coronary syndrome. SCAD is most common in women <60 years of age (≥90% of cases) compared with men (10-12%). The rapid development of technologies used in interventional cardiology has made it possible to improve diagnostics and understand the pathogenesis. The management strategy in patients with SCAD is debatable and differs significantly from approaches to coronary atherosclerosis treatment. The review presents the results of recent studies. The angiographic classification of SCAD, the diagnostic algorithm and the choice of optimal treatment depending on clinical manifestations are also described.
Effective drug modification of risk factors in a patient with coronary artery disease: a case report
Authors: Galyavich A. S. , Baleeva L. V. , Galeeva Z. M. , Sabirzyanova A. A.
Published: September 2022

The basis of conservative treatment of stable coronary artery disease is the elimination of modifiable risk factors and complex drug therapy for hypertension, diabetes, and dyslipidemia. The rates of awareness, treatment and control of these parameters in Russia remain low. In this regard, current guidelines suggest a step-by-step personalized approach to achieve optimal risk factor control. The aim of this work was to demonstrate that the modification of therapy to achieve the targets of blood pressure, low-density lipoprotein cholesterol and glycated hemoglobin, lifestyle change with smoking cessation, increased physical activity and weight loss led to improvement of coronary circulation and elimination of angina episodes.
Comparison of inhospital outcomes after open thrombectomy versus conservative therapy in patients with acute lower limb artery thrombosis and COVID-19
Authors: Abdullaev I. A. , Abasova S. V. , Danilchuk L. B. , Shramko V. A. , Sokolova E. V. , Korotkikh A. V. , Zharova A. S. , Kokaya R. V. , Kazantsev A. N.
Published: September 2022

Aim. Comparative analysis of inhospital outcomes after open thrombectomy versus conservative in patients with acute lower limb artery thrombosis and coronavirus disease 2019 (COVID-19).

Material and methods. In this retrospective, comparative study for the period from April 1, 2020 to December 1, 2021, 167 patients with acute lower limb artery thrombosis and COVID-19 were included. Depending on the treatment strategy, two following groups were formed: group 1  — open thrombectomy (n=136) + drug treatment (anticoagulant (unfractionated heparin) and antiplatelet (acetylsalicylic acid 125 mg 1 time per day) therapy; group 2  — only drug therapy (n=31). This group consisted of patients who refused surgical revascularization. In all cases, a psychiatrist examined for personality disorders that did not allow a critical assessment of their condition and the consequences of refusing surgical treatment. At admission to the hospital, all patients received prophylactic-dose unfractionated heparin (5000 IU 3 times/day). In the development of acute arterial thrombosis, 80 IU/kg (maximum 5000 IU) of unfractionated heparin was administered intravenously, followed by transfer to intravenous infusion at an initial rate of 18 IU/kg per hour with the partial thromboplastin time monitoring. Analgesic and antiplatelet therapy (acetylsalicylic acid 125 mg 1 time/day) was also prescribed.

Results. Myocardial infarctions, ischemic strokes were not recorded. There were no significant intergroup differences in mortality rates (group 1: n=52, 38,2%; group 2: n=7, 22,6%; p=0,09; odds ratio (OR)=2,12; 95% confidence interval (CI): 0,85-5,27), limb amputation (group 1: n=63, 46,3%; group 2: n=9, 29,0%; p=0,07; OR=2,11; 95% CI: 0,9-4,91). However, there was a trend towards a decrease in the frequency of these events in the conservative therapy group. After open thrombectomy, retrombosis developed in 50,7% (n=69) of cases, whilethrombosis after retrombectomy followed by amputation  — in 46,3% (n=63). There were no hemorrhagic complications in both groups.

Conclusion. Open thrombectomy with concomitant medical therapy and single conservative therapy without surgical revascularization in the present study showed comparable rates of death and lower limb amputations in patients with COVID-19.
The Undergraduate Games Corpus: A Dataset for Machine Perception of Interactive Media
Authors: Anderson Barrett R. , Smith Adam M.
Published: September 2022

Machine perception research primarily focuses on processing static inputs (e.g. images and texts). We are interested in machine perception of interactive media (such as games, apps, and complex web applications) where interactive audience choices have long-term implications for the audience experience. While there is ample research on AI methods for the task of playing games (often just one game at a time), this work is difficult to apply to new and in-development games or to use for non-playing tasks such as similarity-based retrieval or authoring assistance. In response, we contribute a corpus of 755 games and structured metadata, spread across several platforms (Twine, Bitsy, Construct, and Godot), with full source and assets available and appropriately licensed for use and redistribution in research. Because these games were sourced from student projects in an undergraduate game development program, they reference timely themes in their content and represent a variety of levels of design polish rather than only representing past commercial successes. This corpus could accelerate research in understanding interactive media while anchoring that work in freshly-developed games intended as legitimate human experiences (rather than lab-created AI testbeds). We validate the utility of this corpus by setting up the novel task of predicting tags relevant to the player experience from the game source code, showing that representations that better exploit the structure of the media outperform a text-only baseline.
Differentially Private Link Prediction with Protected Connections
Authors: De Abir , Chakrabarti Soumen
Published: September 2022

Link prediction (LP) algorithms propose to each node a ranked list of nodes that are currently non-neighbors, as the most likely candidates for future linkage. Owing to increasing concerns about privacy, users (nodes) may prefer to keep some of their connections protected or private. Motivated by this observation, our goal is to design a differentially private LP algorithm, which trades off between privacy of the protected node-pairs and the link prediction accuracy. More specifically, we first propose a form of differential privacy on graphs, which models the privacy loss only of those node-pairs which are marked as protected. Next, we develop DPLP, a learning to rank algorithm, which applies a monotone transform to base scores from a non-private LP system, and then adds noise. DPLP is trained with a privacy induced ranking loss, which optimizes the ranking utility for a given maximum allowed level of privacy leakage of the protected node-pairs. Under a recently introduced latent node embedding model, we present a formal trade-off between privacy and LP utility. Extensive experiments with several real-life graphs and several LP heuristics show that DPLP can trade off between privacy and predictive performance more effectively than several alternatives.
Community-Aware Multi-Task Transportation Demand Prediction
Authors: Liu Hao , Wu Qiyu , Zhuang Fuzhen , Lu Xinjiang , Dou Dejing , Xiong Hui
Published: September 2022

Transportation demand prediction is of great importance to urban governance and has become an essential function in many online applications. While many efforts have been made for regional transportation demand prediction, predicting the diversified transportation demand for different communities (e.g., the aged, the juveniles) remains an unexplored problem. However, this task is challenging because of the joint influence of spatio-temporal correlation among regions and implicit correlation among different communities. To this end, in this paper, we propose the Multi-task Spatio-Temporal Network with Mutually-supervised Adaptive task grouping (Ada-MSTNet) for community-aware transportation demand prediction. Specifically, we first construct a sequence of multi-view graphs from both spatial and community perspectives, and devise a spatio-temporal neural network to simultaneously capture the sophisticated correlations between regions and communities, respectively. Then, we propose an adaptively clustered multi-task learning module, where the prediction of each region-community specific transportation demand is regarded as distinct task. Moreover, a mutually supervised adaptive task grouping strategy is introduced to softly cluster each task into different task groups, by leveraging the supervision signal from one another graph view. In such a way, Ada-MSTNet is not only able to share common knowledge among highly related communities and regions, but also shield the noise from unrelated tasks in an end-to-end fashion. Finally, extensive experiments on two real-world datasets demonstrate the effectiveness of our approach compared with seven baselines.
Asynchronous Stochastic Gradient Descent for Extreme-Scale Recommender Systems
Authors: Liu Lewis , Zhao Kun
Published: September 2022

Recommender systems are influential for many internet applications. As the size of the dataset provided for a recommendation model grows rapidly, how to utilize such amount of data effectively matters a lot. For a typical Click-Through-Rate(CTR) prediction model, the amount of daily samples can probably be up to hundreds of terabytes, which reaches dozens of petabytes at an extreme-scale when we take several days into consideration. Such data makes it essential to train the model parallelly and continuously. Traditional asynchronous stochastic gradient descent (ASGD) and its variants are proved efficient but often suffer from stale gradients. Hence, the model convergence tends to be worse as more workers are used. Moreover, the existing adaptive optimizers, which are friendly to sparse data, stagger in long-term training due to the significant imbalance between new and accumulated gradients.

To address the challenges posed by extreme-scale data, we propose: 1) Staleness normalization and data normalization to eliminate the turbulence of stale gradients when training asynchronously in hundreds and thousands of workers; 2) SWAP, a novel framework for adaptive optimizers to balance the new and historical gradients by taking sampling period into consideration. We implement these approaches in TensorFlow and apply them to CTR tasks in real-world e- commerce scenarios. Experiments show that the number of workers in asynchronous training can be extended to 3000 with guaranteed convergence, and the final AUC is improved by more than 5 percentage.
RareBERT: Transformer Architecture for Rare Disease Patient Identification using Administrative Claims
Authors: Prakash PKS , Chilukuri Srinivas , Ranade Nikhil , Viswanathan Shankar
Published: September 2022

A rare disease is any disease that affects a very small percentage (1 in 1,500) of population. It is estimated that there are nearly 7,000 rare disease affecting 30 million patients in the U. S. alone. Most of the patients suffering from rare diseases experience multiple misdiagnoses and may never be diagnosed correctly. This is largely driven by the low prevalence of the disease that results in a lack of awareness among healthcare providers. There have been efforts from machine learning researchers to develop predictive models to help diagnose patients using healthcare datasets such as electronic health records and administrative claims. Most recently, transformer models have been applied to predict diseases BEHRT, G-BERT and Med-BERT. However, these have been developed specifically for electronic health records (EHR) and have not been designed to address rare disease challenges such as class imbalance, partial longitudinal data capture, and noisy labels. As a result, they deliver poor performance in predicting rare diseases compared with baselines. Besides, EHR datasets are generally confined to the hospital systems using them and do not capture a wider sample of patients thus limiting the availability of sufficient rare dis-ease patients in the dataset. To address these challenges, we introduced an extension of the BERT model tailored for rare disease diagnosis called RareBERT which has been trained on administrative claims datasets. RareBERT extends Med-BERT by including context embedding and temporal reference embedding. Moreover, we introduced a novel adaptive loss function to handle the class imbal-ance. In this paper, we show our experiments on diagnosing X-Linked Hypophosphatemia (XLH), a genetic rare disease. While RareBERT performs significantly better than the baseline models (79.9% AUPRC versus 30% AUPRC for Med-BERT), owing to the transformer architecture, it also shows its robustness in partial longitudinal data capture caused by poor capture of claims with a drop in performance of only 1.35% AUPRC, compared with 12% for Med-BERT and 33.0% for LSTM and 67.4% for boosting trees based baseline.