bluuebunny/crossref_metadata_2025 huggingface dataset:
Follistatin-like I promotes endometriosis by increasing proinflammatory factors and promoting angiogenesis
Authors: Lei Sha-Ting , Li Ming-Qing , Cao Yan-Ling , Hou Shu-Hui , Peng Hai-Yan , Zhao Dong , Sun Jing
Published: December 2021

Endometriosis (EMS) is a chronic benign inflammatory disease characterized by the growth of endometrial-like tissue in aberrant locations outside of the uterine cavity. Angiogenesis and abnormal immune responses are the fundamental requirements of endometriotic lesion survival in the peritoneal cavity. Follistatin-like I (FSTL1) is a secreted glycoprotein that exhibits varied expression levels in cardiovascular disease, cancer and arthritis. However, the role of FSTL1 in the development of EMS remains to be fully elucidated. Results of the present study demonstrated that the expression of FSTL1 was significantly increased in ectopic endometrial stromal cells (ESCs) and peritoneal fluid from patients with EMS, compared to the control group. Both conditions of hypoxia and estrogen treatment induced human ESCs to produce increased levels of FSTL1 and disco-interacting protein 2 homolog A (DIP2A). Furthermore, the expression levels of DIP2A, IL8 and IL1β were increased in FSTL1 overexpressed HESCs. Additionally, FSTL1 treatment increased the proliferation of HUVECs in a dose-dependent manner in vitro and markedly increased the tube formation of HUVECs. Moreover, treatment with FSTL1 facilitated M1 polarization of macrophages, increased the secretion of proinflammatory factors and inhibited the expression of scavenger receptor CD36. Results of the present study suggested that the elevated expression of FSTL1 may play a key role in accelerating the development of EMS via enhancing the secretion of proinflammatory factors and promoting angiogenesis.
Dimensional stability improvement of corn stalk biocomposites using two-part lignin-derived binder optimized with response surface methodology
Authors: Yuan Yuan , Li Sidan , Jiao Feng , Shen Guinan , Yan Lei , Wang Weidong
Published: December 2021

To strengthen the dimensional stability of enzymatically treated corn stalk (ECS) biocomposites, hybrid modified lignosulfonate (HML) was used as a binder to fabricate reinforced ECS/HML composites with evaluation by response surface methodology. The effects of the preparation treatment on the enzymatic conditions, as well as the modified lignosulfonate dosage on the physicomechanical properties of the ECS/HML composites, were all evaluated. The optimum preparation parameters were determined via the Box-Behnken experimental design. High mass concentrations of laccase-vanillin and an appropriate modified lignosulfonate dosage for a relatively short enzymatic pretreatment time led to reduced residual stresses and improved dimensional properties. The optimum conditions that minimized thickness swelling (TS) and water adsorption (WA) without significantly compromising the biocomposite mechanical properties were determined to be 25 g/L laccase-vanillin, 118.8 min enzymatic pre-treatment time, and 15 wt% modified lignosulfonate. The ECS/HML composites that were treated under the optimal conditions resulted in an approximate 42% reduction in the dimensional properties without any significant decline in mechanical properties when compared to ECS panels. Unlike the loose structure of ECS biocomposites, the ECS/HML composites had a laminar shape with firm morphology.
Design of a modified charcoal production kiln for thermal therapy and evaluation of the charcoal characteristics from this kiln
Authors: Lee Hui Su , Jeon Woo Seok , Kim Yun Ki , Purusatama Byantara Darsan , Kim Ah Ran , Cho Jae Ik , Kim Wae Jung , Kim Hyung Chun , Kim Nam Hun
Published: December 2021

A modified charcoal kiln was developed for both thermal therapy and charcoal production. The design of a modified kiln for thermal therapy focused on safety and cleanliness, plus the production of good quality charcoal. Two entrances in the kiln were designed for convenient charcoal production and thermal therapy. A barrier wall designed for noxious gases was installed between the adjoining charcoal kilns for safe thermal therapy. Additionally, a fine dust collector was installed to remove the fine dust generated during charcoal production. To verify the safety of the kiln, fine dust and harmful gases, such as carbon monoxide (CO), carbon dioxide (CO2), nitrogen dioxide (NO2), and radon (Rn), were measured after the charring process. The quality of the charcoal produced in the thermal therapy kiln was also examined. To evaluate charcoal quality, some physical properties and results from a proximate analysis were evaluated using Korean standards. The measurements of harmful substances and fine dust in the modified charcoal kiln met the criterion of the Ministry of Environment Clean Air Conservation Act in Korea. In addition, there were no noticeable differences in the monthly charcoal characteristics prepared from the thermal therapy kiln, and the charcoal characteristics also met the reference values of the Korea Forest Service.
Evaluation of hemolysis during storage of red blood cell concentrates processed by centrifugation and settling method by simple gravity in Burkina Faso
Authors: Sawadogo Salam , Moindze Aboudou , Nebie,  Koumpingnin , Kafando Amadou , Sawadogo Abdoul-Guaniyi , Ouili Patrice , Kafando Eléonore
Published: December 2021

Background: Hemolysis is one of the red blood cell concentrates (RCCs) storage concerns. In Burkina Faso, hemolysis rate was not routinely assessed in RCCs. Our study aimed at assessing the degree of hemolysis in RCCs processed by centrifugation (centrifuged RCCs) and whole blood settling by simple gravity (Sedimented RCCs) in Burkina Faso. Methods: We conducted a cross-sectional comparative study on 46 prepared by centrifugation and 46 prepared by sedimentation, matched on their collection date and initial volume of whole blood. The hemolysis percent was measured on Days 0, 7, 14, 21, 28 and 32. Results: In the centrifuged RCCs, the hemolysis percent on D0 was 0.232% versus 0.199% for the sedimented RCCs (p = 0.046). At D32, the average hemolysis percent was 835% for the sedimented RCCs and 0.779% for the centrifuged RCCs (p = 0.042). The degree of hemolysis increased gradually between D0 and D32 with an average increase of 0.120% for centrifuged RCCs and 0.116% for sedimented RCCs. Conclusion: The degree of hemolysis at D32 in both centrifuged RCCs and sedimented RCCs falls below standards. Therefore, it necessary to revisit blood components processing procedures, focusing on the centrifugation parameters and the handling conditions.
Dubin Johnson Syndrome associated with defective ristocetin – induced platelet agglutination
Authors: Elfiky Samar Mohamad , Sahmoud Shaimaa Ismail
Published: December 2021

Background: This is the first reported case of platelet aggregation defect in association with Dubin-Johnson Syndrome. Case presentation: We reported a 14 months old female infant with recurrent attacks of mild to moderate ear and nose bleeding and moderate amount of subarachnoid hemorrhage with ristocetin induced platelet agglutination other than Von Willebrand Factor disease and Bernard–Soulier syndrome. The patient also had fluctuating bilirubin level (Maximum of 15 mg/dl) and remaining liver function tests were normal; the patient diagnosed as Dubin Johnson Syndrome by liver biopsy. Conclusions: Dubin-Johnson Syndrome may be associated with platelet aggregation defect.
Skin and subcutaneous cell tissue bacterial infections in newborns
Authors: Oliveira Rocha Bruno de
Published: December 2021

Bacterial skin infections are especially common in children of tropical regions, varying clinically from a process superficial (such as folliculitis), to a deeper infection (such as necrotizing fasciitis). Infections of skin and subcutaneous tissue are frequent reasons for medical consultations in primary health care services and hospitalization in pediatric patients. In neonates several factors confer an increased susceptibility to bacterial infections of the skin and its complications. Herein, we review essential aspects of the main bacterial skin infections in newborns and nurselings.
Mas Receptor Agonist AVE0991 increases surfactant protein expression under hyperoxic conditions in human lung epithelial cells
Authors: Thiruvenkataramani Ranga Prasanth , Abdul-Hafez Amal , Gewolb Ira , Uhal Bruce
Published: December 2021

Background: Hyperoxia in pre-term neonates is a known risk factor of bronchopulmonary dysplasia (BPD). Hyperoxia is known to cause oxidative stress, inflammatory changes that leads to surfactant deactivation, and decreased surfactant expression. The previous research has shown short term exposure to hyperoxia increases surfactant protein expression but decreased expression in long term exposure. Local tissue renin-angiotensin system (RAS) is associated with tissue injury and repair and it may play a role in BPD. Endogenous peptide angiotensin 1-7 acts on the MAS receptor. The activation of the MAS receptor was previously shown to have protective pulmonary responses. However, the effect of MAS receptor activation on surfactant proteins in hyperoxic conditions has not been tested. Objective: To determine the effects of hyperoxia with or without MAS receptor activation on Surfactant proteins. Methods: Human epithelial cell line A549 and human primary alveolar epithelial cells (AECs) were cultured to sub-confluence (60-75%) and treated with hyperoxia (95% oxygen) and normoxia (21% oxygen) for 72 hours with or without the MAS receptor agonist (AVE0991) in serum-free F-12 nutrient media. Cells were lysed and cell lysates were collected for western blot. The statistical analysis was done using Student-Newman-Keuls Multiple comparison test. Results: Surfactant protein concentration increased in AVE treated group under the hyperoxic condition when compared to the control group in both A549 cells and human primary AECs. Surfactant protein was in higher concentration in AVE0991 treated cells in both hyperoxic and normoxic conditions when compared to the non-treated control group. Conclusions: MAS receptor activation via AVE0991 causes an increase in Surfactant protein concentration in both hyperoxic and normoxic conditions. As per our experiments, hyperoxic conditions decrease the production of surfactant protein when compared to normoxic conditions. These results may reveal a novel potential drug for BPD treatment and decrease its severity.
Cardio-Respiratory tolerability of perfluoropropaneEnhanced MRI of pulmonary ventilation
Authors: Mammarappallil, MD, PhD Joseph , Moon MD Richard E. , MacIntyre MD Neil R. , Foster PhD W. Michael , Womack MS Samantha J. , Ainslie MS RT(R)MR Maureen D. , McAdams, MD H. Page , Halaweish PhD Ahmed F. , Choudury PhD Kingshuk , Charles PhD H. Cecil
Published: December 2021

Rationale: Recent advances in perfluoropropane magnetic resonance imaging of the lung have provided the means to assess pulmonary ventilation and gas distribution throughout the pulmonary airways and acini in a non-invasive manner. Objectives: The increased density of the inhaled PFP/O2 gas mixture generates longer wash-in times compared to wash-out while breathing room air and leads to slight increases in airway resistance (Raw) and respiratory effort by the subject during imaging. As a consequence of these gas-related effects, we sought to evaluate the cardio-respiratory tolerability of the PFP/O2 gas mixtures in our sequential breath-hold imaging protocol in normal subjects and subjects with obstructive lung disease. Methods: Tolerability was determined by evaluation of changes in vital signs (Heart Rate, Systolic and Diastolic Blood Pressure, Respiratory Rate and Temperature (otic)) at 3 time points (screening, pre-imaging and post-imaging) Measurements and Main Results: Assessment of vital signs before and after the administration of perfluoropropane gas mixture by matched pair analysis demonstrated statistically different values for Heart rate (Mean Difference =-2.417 bpm), Systolic BP (Mean Difference=6.95 mmHg), Diastolic BP (Mean Difference=3.86 mmHg) and SpO2 (Mean Difference=0.56%) even though these do not represent physiologically significant differences compared to activities of daily living such as climbing a flight of stairs. Conclusions: Our data demonstrate no negative outcomes in using PFP gas to image pulmonary ventilation. The PFP gas mixture is safe, well tolerated, and provides a three dimensional ‘picture’ (representation) of inhaled gas distribution for subject cohorts of normal and obstructive lung disease.
Utilization of pulmonary rehabilitation for everyone
Authors: McCain Kent
Published: December 2021

Knowledge and therapy for patients with respiratory illnesses has been ongoing in the medical world. Assisting with the patient’s quality of life and possible recovery is a type of rehab that includes education as well as monitored exercise. This rehab notably labeled Pulmonary Rehab is managed by healthcare workers with the intent on assisting the patient to not only get up and move, but to remain social. Quarantine and the threat of being infected with Covid-19 put a halt to programs like this. As people were searching for ways to see their physicians for appointments and telehealth was approved for most, it was not for Pulmonary Rehab. These patients that had been placed in a program to ensure they would have interaction, were now just shut in their homes. Pulmonary Rehab should be open to all not being approved now because of insurance or other details such as financial or telehealth issues.
Warning with chronic subdural hematomas in the elderly
Authors: Phuong Hoai Dinh Thi , Dung Nguyen Thi My , Cuong Hoang Manh , Kieu Oanh Huynh Thi , Tram Ngo Thuy , Nhung, Nguyen Thi , Lac Nguyen Vinh , Minh Nguyen Thanh
Published: December 2021

Chronic subdural hematoma (cSDH) is a disorder in which blood collects between the dura and arachnoid mater of meninges around the brain. It's more common among the elderly and usually triggered by a head injury. We report a case of a 78-year-old male patient who had previously been diagnosed with a left hemisphere subdural hematoma for no apparent reason with a history of hypertension. Two days before hospitalizing, he had a symptom of weakness in the right extremities. Non-contrast CT of head reveals a crescent-shaped, heterodense lesion over the lateral aspect of the left hemisphere measuring 11x5x1 cm with mass effect to the adjacent brain parenchyma. Burr hole drainage was performed for the patient. His symptoms improved after the surgery.
New approach of chemotherapy for the treatment of retinoblastoma: a review
Authors: AK Ghosh , Gupta SP Das
Published: December 2021

Retinoblastoma is the most common primary intraocular malignancy of childhood. A potentially curable cancer, its treatment has improved significantly over the last few decades. In developed world current treatment options aim to preserve the globe as well as vision with minimum morbidity. High resolution imaging has improved tumor detection and is useful for prognosticating cases and monitoring response to treatment. Targeted chemotherapy has shown promising results and these routes are being increasingly employed world-wide for globe preservation. Chemotherapy is currently used as a first line approach for children with this malignancy and can be delivered by intravenous, intra-arterial, periocular, and intravitreal routes. The choice of route for chemotherapy administration depends upon the tumor laterality and tumor staging. This review aims to highlight newer advancements in the field of management of retinoblastoma that have been introduced in recent times, with a special emphasis on globe-preserving therapy.
Migration of urolift clip into the bladder causing haematuria 3-years after insertion: a rare delayed complication of prostatic urolift
Authors: Krishnendu Biswas , Rajiv Pillai
Published: December 2021

Prostatic UroLift placement as a minimally invasive technique for the treatment of bladder outlet obstruction due to benign enlargement of prostate has been well accepted in literature and is practised with minimal post-operative complications. We present an unusual cause of haematuria due to migration of one of the prostatic UroLift clips into the bladder after 3 years from its insertion and its subsequent endourological management. To our knowledge, delayed migration of UroLift clip causing haematuria has not been reported in literature in the past. Urologists should be aware of this possible situation while dealing with patients with UroLift implanted.
Sharika D. Crawford. The Last Turtlemen of the Caribbean.
Authors: Leal Claudia
Published: December 2021

La gran mayoría de los colombianos vive entre paisajes andinos y pisando siempre tierra firme. Los intelectuales de “la” costa (así conocida, aunque no tenemos una sino dos) llevan décadas insistiendo en que el país no es solo andino sino también caribeño. Nos han recordado que, para aprehender cabalmente nuestro territorio y reconocer quiénes somos, debemos tener en cuenta las complejas redes que desde el siglo xvi le han dado forma al Gran Caribe insular y continental. Para quienes, como yo, estamos alejados del mar en cuerpo y espíritu (por hermoso que nos parezca), el libro The Last Turtlemen de Sharika Crawford nos sumerge en el territorio acuático del Caribe y nos permite pensar a Colombia desde una perspectiva inusual: de la mano de los cazadores de tortugas oriundos de las Islas Caimán.
Joanne Rappaport. El cobarde no hace historia. Orlando Fals Borda y los inicios de la investigación-acción participativa.
Authors: Archila Neira Mauricio
Published: December 2021

Este nuevo libro de Joanne Rappaport continúa su acercamiento a las luchas agrarias —especialmente indígenas— en Colombia y a las formas de conocimiento que se producen en torno a ellas. Lo define como una historia etnográfica de los inicios de la Investigación Acción Participativa (IAP) impulsada por Orlando Fals Borda en el sur de la costa atlántica a principios de los años setenta. A nuestro juicio, esta obra es un ejercicio de IAP sobre los orígenes de la IAP, aunque no en sentido literal, pues muchos de los interlocutores, comenzando por Fals Borda, ya no están entre nosotros.
Real-time implementation of Fuzzy Logic Controller based on chicken swarm optimization for the ball and plate system
Authors: Oglah Ahmed A. , Msallam Mohammed Majid
Published: December 2021

The ball and Plate (BaP) system is the typical example of the nonlinear dynamic system that is used in a wide range of engineering applications. So, many researchers in the control field are using the Bap system to check robust controllers under several points that challenge it, such as internal and external disturbances. Our manuscript proposed a position control intelligent technique with two directions (2D) for the BaP system by optimized multi Fuzzy Logic Controllers (FLC’s) with Chicken Swarm Optimization (CSO) for each one. The gains and rules of the FLC’s can tune based on the CSO. This proposal utilizes the ability of the FLC’s to observe the position of the ball. At our work, the BaP system that belonged to Control Laboratory/Systems and Control Engineering department is used for real-time proposal implementation. The results have been showing a very good percentage enhancement in settling time, rise time, and overshoot, of the X-axis and Y-axis, respectively.
Use of algorithms in BIM-based audit processes
Authors: Máder Patrik Márk , Rák Olivér , Bakai Nándor , Etlinger József , Zagorácz Márk , Háber István Ervin
Published: December 2021

Building information modeling is a complex and structure-based methodology. It applies predefined steps and frameworks; however, an audit procedure can be complicated and time-consuming. The steps of the evaluations are based on logical connections that also form algorithms in a manual workflow. Algorithms can be interpreted by computers with the help of software languages. A higher level of automation, more efficient workflows, and more economical and accurate results can be developed by using algorithms.
Influence of the Pandemic on Change of Everyday Practices of Volgograd Residents: Gender Differences (Based on the Results of Applied Sociological Research)
Authors: Dulina Nadezhda , Anufrieva Eugeniya
Published: December 2021

The coronavirus pandemic (COVID-19), which swept the whole, at the very beginning of its spread (early 2020) created an almost experimental situation in which "border practices" were fully revealed, demonstrating the attitude of the population to issues of morality and law. The COVID-19 pandemic that swept the whole word is viewed by us a factor provoking human behavior. The article presents the results of an applied sociological study of changes in the daily practices of Volgograd residents. The results of a sociological study conducted among the residents of Volgograd are presented. Information gathering method – focus group discussion. The main technical parameters of the study are indicated. The formulated conclusions make it possible not only to record the change in the habitual practices of townspeople, but also to present the socioeconomic situation as a whole. Similarities and differences in the behavior of men и women are indicated. So women are more inclined to demonstrate behavior, which can be described as "everything doubtful is prohibited", while men are inclined to a different model – "much controversial is acceptable". Citizens assess the pandemic as a non-standard, undetermined situation, contradictory and inconsistent decisions are made in this case. citizens describe the situation of the pandemic in a negative aspect: distrust of the authorities through the refusal to view the news, violation of personal space, difficulties of interaction and communication in a confined space of the home, fighting their own fears, spending on the purchase of medical devices, antiviral drugs, paying for the Internet. Passive survival models are common, these models are aimed at saving money, more rational spending of the family budget. Active models are not involved due to the lack of jobs in the city. The most unexpected conclusion was that the biggest fear that haunts the city dwellers are the fear of lack of money, which even supplants the fear of contracting the COVID-19.
Social Readiness for the Consequences of the Pandemic: Sociological View
Authors: Voytov Alexander , Gladkov Dmitry
Published: December 2021

The speed of development and transformation of modern society is directly related to the conditions in which people live. The development of science and technology leads to transformations in social structures. The article analyzes the concept of social readiness in relation to the consequences of a number of social transformations, in particular, the coronavirus infection pandemic. Connections, interactions and relationships in all spheres of society have changed dramatically over the past year. These changes in the article are compared with the consequences of the Spanish Flu pandemic, which took place more than a hundred years ago. The article reveals the peculiarities of the perception of quarantine measures, distance learning and other consequences of self-isolation due to coronavirus infection by various categories of citizens, these conclusions are made based on the analysis of qualitative and quantitative sociological data. When disclosing the concept of «social readiness», attention is paid to both internal and external factors - factors of the social environment. Among the external factors, as an example, the measures introduced after the start of the pandemic by the governments of different countries, including the Russian Federation, are given in relation to various categories of citizens. Elderly citizens, the working-age population and students are the object of research of this article. The features of the perception of work in the online format, compulsory and voluntary self-isolation, distance education in departmental and civil universities by students are considered. The empirical basis of the work was semi-structured interviews with representatives of these social groups, a questionnaire survey among one of the categories of citizens, as well as a secondary analysis of sociological research. The conducted research allowed us to conclude that the age and perception of the threat of coronavirus infection for oneself are important internal factors affecting social readiness for the consequences of the pandemic; among the external factors, socialization agents and government measures have a great influence. Promising directions for further research are indicated.
Consolation by Justice: Religious Consciousness of Pandemic Traumatic Events
Authors: Makarov Andrey , Spirin Tikhon
Published: December 2021

The article reviews secular and religious consciousness of the traumatic events of the coronavirus pandemic. Authors use the theory of cultural secularization for distinction of these two types of consciousness. In the modern age, the theory of "multiple worlds" developed, whose authors proved that people live in different worlds, realities and belong to different types of consciousness. The article analyzes two types of consciousness that create different life worlds of those who have these consciousnesses. The ethical component of understanding the universal traumatic event is analyzed in the aspect of the problem of connection between the concepts "consolation" and "justice". Consolation practices have been known since antiquity, and justice as an effect of establishing cosmic order is considered in many world cultures. In times of crisis, archaic layers of social consciousness become actualized, since it is required to use all resources of collective memory. The secular consciousness is characterized by the idea of man-made immanent justice: justice is established by the creators of human laws. Religious consciousness is based on the idea of a transcendental source of justice that is Creator of being who is a transcendental subject. Comprehension of a traumatic event for religious consciousness is a process of its normalization by giving it the quality of a just event that is necessary for ordering the world, restoring balance between the actions of people and the actions of nature. The psyche is calmed down by giving a just meaning by correlating it with the universal law of the Cosmos or the Creator's plan. Religious consciousness will always seek consolation in the aspect of the relationship between the immanent and transcendental levels of being, since its world is fundamentally dual, metaphysical.
Social Isolation Challenge: Russian Context
Authors: Strizoe Alexander
Published: December 2021

The article considers the main trends and features of the impact of social isolation measures in a global pandemic on the life of modern society. The author notes that the practice of implementing measures of social isolation distinguishes certain social strata, pushing others to the periphery of managerial attention and support; aggravates feelings of social inequality of opportunity, changes space and intensity of individual and social mobility; affects the authority of local and regional government and attitudes towards them. The article describes various aspects and difficulties of individual and social adaptation to the pandemic. The carried out comparative analysis of European and Russian sociocultural context, in which social challenges of the pandemic are manifested, shows their common features: aggravation of problems of social adaptation, different degrees of readiness for it, an asynchronous development of integration processes, an authoritarian-conservative turn in the mass consciousness. The characteristic of the main trends of changes in consciousness and behavior is given, in which the response of Russian society to the challenges of new living conditions and the pandemic reformatting of the social communications space is manifested. The attention to the multidirectional character of adaptation strategies of the population is drawn. The author expresses the opinion that the choice of the optimal variant of society's adaptation to global environmental, including pandemic, challenges is determined both by the elite's ability to transform social institutions and by a change in the dominant personality type. An atomized type of individual, focused on the values of early modernity, in whose subconsciousness authoritarian-paternalistic attitudes are preserved, should be replaced by a type of personality, with qualities and abilities corresponding to the imperatives of a complex and dynamically changing modern society.
Forecasting the Risks of an Organization Operating Natural Gas Vehicles Using a Scoring Model of Logistic Regression in the Presence of Expert Restrictions
Authors: Evstifeev Andrey
Published: December 2021

The paper proposes a method and describes a mathematical model for express analysis of the attractiveness of the operation of vehicles running on natural gas for a motor transport company. The proposed solution is based on a logistic regression scoring model used by banks to assess the creditworthiness of a borrower. To improve the quality of the results, the model is extended with a set of expert restrictions formulated in the form of rules. During the analysis, signs were identified that require quantization, since individual intervals of values ??turned out to be associated with risk in different ways. The developed mathematical model is implemented in the form of software in a high-level programming language, the information of the model is stored in a database management system and is integrated with an information system for supporting management decisions when operating vehicles on natural gas. The developed athematical model was tested on a test training sample. The test results showed a satisfactory accuracy of the proposed model at the level of 77 % without the use of expert restrictions and 79 % with their use. At the same time, the share of Type II errors was 2.7 %, and Type I errors were 7.2 %, which indicates that the model is quite conservative, and a relatively high proportion of vehicles that meet the requirements were rejected.
Simplified assessment of central auditory processing in individuals presented with trisomy 21
Authors: Lima Daviany Oliveira , Rosa Marine Raquel Diniz da , Buriti Ana Karina Lima , Silva Marllon dos Santos Moura e , Miranda Amanda Camâra , Delgado Isabelle Cahino , Araújo Aline Menezes Guedes Dias de
Published: December 2021

ABSTRACT Purpose: to analyze the performance of individuals with trisomy 21 (T21) in the simplified assessment of central auditory processing, identify the impaired skills, and compare it with the results of the hearing self-perception questionnaire administered to the parents. Methods: a descriptive, observational, quantitative study conducted at the Speech-Language-Hearing Teaching Clinic of a public university. The sample comprised 16 individuals with T21, aged 8 to 33 years. Simplified assessment tests of central auditory processing were conducted, namely, sounds localization and sequential memory for verbal and nonverbal sounds, diotically. Then, the Scale of Auditory Behaviors (SAB) was administered to the subjects’ parents/guardians. The descriptive statistical analysis with the chi-square test considered p<0.05. Results: in the simplified assessment, 81.3% had abnormal results in the memory tests for verbal sounds; 75%, in the memory tests for nonverbal sounds; and 37.5%, in the sound localization test. In the Scale of Auditory Behaviors, 62.5% of the answers indicated changes in the central auditory processing, demonstrating that the scale can be useful to identify such changes. However, there was no significant association between the questionnaire and the behavioral test results. Conclusion: the results point to impaired sequential memory skills for verbal and nonverbal sounds in most individuals assessed. The simplified assessment results indicate the need for assessments of central auditory processing. Hence, the simplified assessment is highly important to detect possible changes in the central auditory processing that might interfere with the communication and overall learning of individuals presented with trisomy 21.
Scale of Perception and Analysis of Reading Fluency - SOLAR: usability and consistency
Authors: Alves Luciana Mendonça , Dias Rafael Teixeira Scoralick , Lara Júlia Barcelos , Santos Luiz Felipe dos , Celeste Leticia Corrêa , Martins-Reis Vanessa de Oliveira
Published: December 2021

ABSTRACT Objective: to analyze the consistency of responses of evaluators and to verify the usability of the perception and analysis of SOLAR (Science of Language and Reading) Methods: a non-experimental descriptive cross-sectional study. Elementary school teachers and undergraduate students of speech therapy and pedagogy participated as the judges. The judges used the SOLAR Scale as an instrument to analyze the reading fluency of twenty audios recorded by elementary school students. Usability comparisons were performed using the Kruskal Wallis test and two-by-two comparisons using the Mann Whitney test. To analyze the consistency of the responses between the judges, the calculation of the interclass correlation coefficient was used. Results: the analysis of the reliability of the answers showed an excellent intraclass correlation coefficient for all the skills of the Scale. As for the usability of the Scale, more than 80% of the participants positively evaluated the assessment. This was verified through the usability questionnaires which confirmed that it was easy to use, with clear guidelines and that users felt comfortable and confident using it. Conclusion: SOLAR obtained good results in reliability and consistency with excellent agreement between the evaluators. These results indicated satisfactory reliability of the SOLAR items and favorable qualitative ratings from users.
GUSTAVO CAPANEMA E O ENSINO SECUNDÁRIO NO BRASIL: A INVENÇÃO DE UM LEGADO
Authors: Montalvão Sérgio de Sousa
Published: December 2021

Resumo Este artigo coloca um problema para a história política da educação: qual seria o indicativo da opção em fazer do ensino secundário o ramo mais atrativo do ensino médio, em um tempo de mudança acelerada para um protótipo de uma sociedade de massas, organizada em torno de um incipiente mercado de trabalho livre, alavancado pelo crescimento da produção industrial e do modo de vida urbano? Apesar dos resultados controversos dessa opção, incapaz de romper com o modelo educacional elitista, um trabalho de construção social da memória fez com que a reforma organizada pelo ministro Gustavo Capanema em 1942 fosse reconhecida como sinônimo da educação de qualidade. Neste sentido, entender as relações do Estado modernizador com os setores mais conservadores da sociedade, fortemente representados pelas instituições educacionais privadas, reprodutoras dos processos escolares de seletividade social, pode ser um caminho frutífero de pesquisa.
Utilização de software para terapia fonoaudiológica com crianças surdas
Authors: Delsin Patrícia Vilela , Lima Maria Cecília Marconi Pinheiro , Constantini Ana Carolina
Published: December 2021

RESUMO Na perspectiva de se trabalhar o aprimoramento da fala de crianças com surdez, a atuação fonoaudiológica busca novas ferramentas condizentes com o cenário tecnológico atual, utilizando-se de aplicativos tecnológicos no auxílio de suas intervenções, pois os jogos digitais, além de estimular a percepção visual, favorecem momentos interativos como etapas do processo de aprendizagem. O presente estudo se propôs a analisar estratégias terapêuticas mediadas pelo uso de software na reabilitação das habilidades vocais e articulatórias de fala de crianças com surdez, usuárias de implante coclear. Tratou-se de pesquisa do tipo estudo de caso com três crianças, realizada por meio do levantamento de prontuário; avaliação da voz e da articulação e análise acústica das produções vocais das vogais [a], [i] e [u] e dos sons oclusivos [p] e [b]; aplicação do jogo digital VoxTraining para aprimoramento de aspectos vocais e de fala, realizada em cinco sessões terapêuticas. Observou-se que todas as crianças tiveram diagnóstico de perda auditiva e início de reabilitação tardios, estavam em fase de aquisição da Língua Brasileira de Sinais como língua materna e apresentavam alterações vocais e articulatórias. Os resultados sugerem que os participantes se interessaram pelo software devido às solicitações de repetição dos jogos e estes contribuíram para melhor entendimento sobre o exercício vocal e articulatório realizado, devido ao estímulo do feedback visual. Conclui-se que o trabalho com crianças surdas utilizando jogos digitais facilitam a terapia e proporcionam melhora na qualidade da voz e da fala.
La Seguridad Social llegó al campo: resistencias y limitaciones en la España del segundo franquismo (1959-1975)
Authors: Bueno-Vergara Eduardo , Perdiguero-Gil Enrique
Published: December 2021

El objetivo del artículo es analizar dos aspectos de la asistencia sanitaria en el medio rural español durante el segundo periodo de la dictadura franquista (1959-1975). Primero analizamos la implantación del Régimen Especial Agrario de la Seguridad Social (1966), que proporcionó asistencia sanitaria a los trabajadores del campo. Hasta entonces, habían sido excluidos del Seguro Obligatorio de Enfermedad (1944), destinado a obreros industriales y otros asalariados con bajos ingresos. En segundo lugar, analizamos la oposición de los médicos rurales a la ampliación de la cobertura sanitaria a los trabajadores agrícolas. Para lograr ambos objetivos analizamos las limitaciones del ejercicio médico en el ámbito rural y cómo la Dictadura intentó solucionar infructuosamente estos problemas. Las fuentes empleadas han sido: disposiciones legislativas, publicaciones de los colegios profesionales oficiales, prensa dedicada a discutir problemas del ejercicio médico, informes sociológicos y documentación de archivo.
JUSTIÇA DE PRIMEIRA E DE SEGUNDA-ORDEM
Authors: Campello Filipe
Published: December 2021

(Este artigo faz parte de um projeto da Trans/Form/Ação: revista de filosofia da Unesp. Trata-se do Dossiê Filosofia Autoral, a ser publicado em 2022.)

Nas últimas décadas, diferentes abordagens ligadas à tradição de(s)colonial têm movido o pêndulo da crítica de pretensões de universalidade para relatos e experiências particulares. Contudo, nisso que podemos chamar de virada narrativa, não é sempre evidente as justificativas morais de perspectivas em primeira pessoa. A questão que gostaria de explorar neste artigo é se seria possível encontrar relevância epistêmica de relatos e experiências subjetivas na crítica de injustiça. Começo por inverter a questão, partindo do problema da objetividade na crítica diante da particularidade das experiências. A questão, neste caso, é de onde fala o filósofo ou a filósofa na sua intenção de descrever experiências de sofrimento de outras pessoas. Se falamos sempre em primeira pessoa, e se existe algum limite cognitivo ou epistêmico de experiências, de onde viria a capacidade de criticar experiências que não são os nossos? Afinal, como podemos compartilhar experiências de injustiça? Em seguida, defendo que podemos avançar se distinguimos duas dimensões de justiça. Seguindo distinções conhecidas de teorias de primeira e segunda ordem, defendo que reinvindicações ligadas à virada narrativa se referem a demandas de justiça de primeira ordem: trata-se de reconhecer moralmente a pretensão epistêmica dos sujeitos, vendo ali a possibilidade de confrontar noções falhas de universalidade e pontos cegos em teorias da justiça. Contudo, essas pretensões não possuem em si próprias critérios de justificação, requerendo dependências normativas que são externas às próprias experiências – essas, sim, situadas em justiça de segunda ordem. Proponho que esse modelo tem a vantagem de tanto incorporar as vantagens teóricas de teorias de(s)coloniais sem negligenciar os potenciais da crítica da injustiça.
CONSCIÊNCIA E CÉREBRO
Authors: Coelho Jonas Gonçalves
Published: December 2021

(Este artigo faz parte de um projeto da Trans/Form/Ação: revista de filosofia da Unesp. Trata-se do Dossiê Filosofia Autoral, a ser publicado em 2022.) A questão sobre a qual me propus a refletir neste artigo é se, e em caso afirmativo, em que termos, uma abordagem fisicalista não-reducionista e interacionista explica a relação entre consciência e cérebro. Para tanto, tomei como fio condutor o problema da lacuna explicativa em sua relação com o problema da lacuna ontológica, o que envolveu duas questões entrelaçadas: 1. A existência de uma lacuna explicativa implica a existência de uma lacuna ontológica? 2. A inexistência de uma lacuna ontológica implica a inexistência de uma lacuna explicativa? Acredito que essa reflexão seja bem-vinda, uma vez que essas duas perspectivas, a epistemológica e a ontológica, muitas vezes se confundem e não são compreendidas.
INTELIGÊNCIA CONTÍNUA
Authors: Santaella Lucia
Published: December 2021

(Este artigo faz parte de um projeto da Trans/Form/Ação: revista de filosofia da Unesp. Trata-se do Dossiê Filosofia Autoral, a ser publicado em 2022.) Minha formação no campo das linguagens, musicais, visuais e verbais foi sempre marcada pela atenção à materialidade das próprias linguagens e aos meios pelos quais elas são transmitidas para permitir suas funções comunicativas. Desde o aparelho fonador, instalado no próprio corpo, esses meios constituem-se como tecnologias que foram evoluindo através dos séculos, trazendo consigo novas formas de linguagem, tais como as distintas formas de escrita, a galáxia de Gutenberg e, do século 19 para cá, as revoluções industrial, eletrônica e digital, cada qual introduzindo tecnologias que lhes são próprias. Quando as questões de linguagem são colocadas no foco da atenção, o que importa, desde a revolução industrial, é o advento de tecnologias cognitivas, como são a fotografia, o cinema, seguidas das tecnologias eletrônicas, rádio e televisão, e, por fim, a explosão da revolução digital com todas as suas novas formas de linguagens e consequentemente de cognição que hoje se distribuem pelos mais distintos aplicativos e plataformas. O estudo dessa evolução levou-me a postular, a partir da inspiração colhida em alguns autores, que a cognição humana está, desde as primeiras formas de escrita, crescendo fora da caixa craniana. Portanto, uma proposta que diz respeito à exossomatização da inteligência e da cognição humana com todas as contradições que isso traz. Este artigo está dedicado à explicitação dessa proposta com atenção ao modo como ela foi se desenvolvendo no meu pensamento.
POR QUE SOMOS O NOSSO CÉREBRO
Authors: Pereira Roberto Horácio de Sá , Souza Filho Sérgio Farias de , Barcellos Victor Machado
Published: December 2021

(Este artigo faz parte de um projeto da Trans/Form/Ação: revista de filosofia da Unesp. Trata-se do Dossiê Filosofia Autoral, a ser publicado em 2022.)

Neste ensaio defenderemos as seguintes teses: 1- o know-how não é uma forma de saber prático destituído de sentido proposicional; 2- a relação entre cada percepção e o corpo próprio é metafisicamente contingente (os organismos e corpos podem variar, como podem inclusive variar os espaços que ocupam em uma mesma experiência), 3- cabe ao cérebro configurar ou moldar um corpo físico (Körper) em um corpo vivo (Leib) e não o inverso; 4- o externismo fenomenal de base enativista, mesmo na sua forma branda, é empiricamente implausível: a correlação entre o caráter consciente da experiência sensorial com padrões neuronais espaço-temporais é muito mais sistemática e regular do que com a correlação com qualquer coisa fora do cérebro. Mas sua na sua forma radical é inteiramente implausível: duplicatas fenomenais não são necessariamente duplicatas de agência; em suma, 5-somos o nosso próprio cérebro que possui um corpo, avatares, e artefatos, devidamente configurados e moldados pelo cérebro, e não um corpo que possui um cérebro dentre outros órgãos.
UMA VISÃO DE MUNDO FILOSÓFICA
Authors: Cid Rodrigo Reis Lastra
Published: December 2021

(Este artigo faz parte de um projeto da Trans/Form/Ação: revista de filosofia da Unesp. Trata-se do Dossiê Filosofia Autoral, a ser publicado em 2022.) O objetivo deste artigo é apresentar uma visão de mundo filosófica, especificamente metafísica. A importância disso é justamente obter uma visão generalista da realidade, em um momento em que as discussões filosóficas se tornam cada vez mais especializadas. A visão de mundo metafísica apresentada aqui é uma perspectiva geral sobre o tempo, o espaço, a matéria, as leis da natureza, a mente e a normatividade. Para realizar esse objetivo, (1) falaremos um pouco sobre a natureza da filosofia e sobre sua relação com a construção de uma visão de mundo, (2) abordaremos alguns argumentos para tratar da natureza das entidades mencionadas, e (3) concluiremos, (a) apresentando uma visão de mundo metafísica unificada, que leva em consideração tais argumentos, e (b) indicando algumas de suas dificuldades adicionais, que se relacionam com a compatibilidade das teorias metafísicas com as melhores teorias científicas.
O PERSPECTIVISMO NEUTRO E A FUNÇÃO BIOLÓGICA DA CONSCIÊNCIA
Authors: Stein Sofia Inês Albornoz
Published: December 2021

(Este artigo faz parte de um projeto da Trans/Form/Ação: revista de filosofia da Unesp. Trata-se do Dossiê Filosofia Autoral, a ser publicado em 2022.)

Neste artigo argumento em favor de uma posição acerca da natureza da mente humana que não é um fisicalismo reducionista e nem tampouco qualquer tipo de dualismo, seja de substância ou de propriedade. Sustento o perspectivismo neutro, inspirado no monismo neutro, de teor cientificista e materialista, que permite incluir experiências fenomênicas conscientes como parte de cadeias causais de processos perceptivos, emocionais, cognitivos e deliberativos. Embora não existam ainda teorias, leis e dados que permitam uma decisão final sobre qual o papel das experiências fenomênicas conscientes em processos físico-químicos do corpo, evidências coletadas nas últimas décadas não apenas fortalecem nossa crença na correlação entre eventos físico-químicos e experiências qualitativas conscientes como também aumentam o número de razões em favor da tese de que essas experiências realmente têm um papel funcional importante nos processos de coleta e uso de informações pelo organismo.
Incidencia de la política monetaria y la tasa de cambio en el crecimiento económico de Colombia
Authors: Martínez Linero Omaira
Published: December 2021

La política monetaria es un instrumento de la política económica de un país que, junto con la política fiscal, la política cambiaria y la política de comercio, utilizan los gobiernos para alcanzar los objetivos económicos de aumentar la riqueza nacional, y contribuir al desarrollo y al bienestar de todos sus nacionales. En este sentido, la política monetaria contribuye a través de la estabilización del valor del dinero en el tiempo y de la balanza de pagos para procurar un crecimiento del producto interno bruto.