bluuebunny/crossref_metadata_2025 huggingface dataset:
Extraction of Lipopeptide from Bacillus subtilis and Histological Study on Albino Rats Tissue
Authors: Ghofran Filaih Abd AL-Hussan  , Waleed Jaleel Abed AL-Kelaby  , Ali Yas Khudhair AL-Ameri
Published: November 2021

Introduction and Aim: An extract of the lipopeptides from Bacillus subtilis has been found to be extremely useful in antimicrobial applications. Specifically, the goal of this study is to manufacture lipopeptide and assess the safety of this substance on the tissues and organs of laboratory rats.

Materials and Methods: Bacillus subtilis bacteria were isolated and identified at the postgraduate microbiology laboratory in the department of biology at Kufa University's College of Science. The bacteria became active after 24 hours of growth in the brain broth infusion broth medium. In order to determine the bacteria's capacity to produce lipopeptide. On nutrient agar medium, a quantity of lipopeptide was synthesized utilizing HCL for sediment, yielding an estimated amount of 1.5 gm during a two-month period, then the product was partially purified and lyophilized using a lyophilizer. For one week, the lipopeptide was administered on albino rat tissues such as the kidney, liver, spleen, and small intestine to determine its safety.

Results: The results showed no damage or any changes on tested tissues compared with control treatment and all of the previously mentioned organ tissues were completely intact and this is evidence of the safety of the lipopeptide extract for use.

Conclusions: It was discovered that lipopeptide had no effect on the organs that were utilized in the experiment and that it is safe for human consumption.
Supporting Students with Sex Chromosome Aneuploidies in Educational Settings
Authors: Thompson Talia , Davis Shanlee , Janusz Jennifer , Frith Erin , Pyle Laura , Howell Susan , Boada Richard , Wilson Rebecca , Tartaglia Nicole
Published: November 2021

Children with sex chromosome aneuploidies (SCAs) are at an increased risk for neurocognitive and behavioral disorders that may interfere with academic success, including early developmental delays, learning disabilities, executive function problems, and social communication deficits. The present national survey aimed to update and extend our understanding of school supports and educational outcomes for students with these increasingly common genetic diagnoses. Parents of children with a diagnosed SCA, birth to 21 years, living in the United States (N = 248), responded to an electronic survey with questions focused on school support plans, academic accommodations, educational therapies, school completion, and perceptions of educator awareness of SCAs. Results revealed high rates of delayed kindergarten, grade retention in primary years, and educational support plans (IEPs = 71%; Section 504 Plans = 26%). A majority (73%) of respondents with children over age 18 years (N = 41) reported their children successfully completed high school, and nearly half (46%) pursued post-secondary education opportunities. Many parents reported their children’s educators had little to no knowledge of SCA conditions, justifying a need to train teachers and policy makers in the unique educational needs of children and adolescents with SCAs. School psychologists should be aware of the frequent need for accommodations and individualized support plans in this population so they can support children and families by advocating for early and comprehensive evaluations and intervention plans.
The upstanding for promotion–prevention (UPP) program: A motivation science approach to encourage active bystanding
Authors: McCarty Shane , Pacque Kyle , Booker Jordan Ashton , Liskey Megan , Arnold Megan
Published: November 2021

Social problems and harmful behaviors can be prevented or mitigated when active bystanders intervene to help. As a result, prevention bystander intervention programs aim to prevent problems related to safety (e.g., sexual violence), health (e.g., injury or death), and justice (e.g., racial discrimination). In contrast, promotion bystander intervention programs aim to promote aspirations and desirable behaviors. This reality led us to develop an integrative Upstanding for Promotion-Prevention (UPP) program based on the decision-making steps of a revised bystander intervention model (i.e., notice an opportunity; interpret the situation; assume responsibility; select a promotion or prevention strategy; take action: Latané & Darley, 1970; McCarty, Arnold, Booker, Pacqué, & Liskey, 2021). Program participants experience a promotion track or prevention track to impact either the promoting pathway by changing assets or the protecting pathway by addressing risks and protective factors. The UPP program offers a motivation science approach to encourage upstanders to promote benefit and prevent harm in schools and on college campuses, within workplaces, online, and throughout communities. Ultimately, existing prevention bystander programs could adopt promotion elements to address safety through peace promotion and violence prevention, health through health promotion and disease prevention, and justice through antiracism promotion and racism prevention.
Mixed Union Formation among 1.5 and Second-generation Immigrants in Denmark: The Role of Cultural Proximity and Opportunity Structures
Authors: Qvist Hans-Peter Y. , Qvist Jeevitha Yogachandiran
Published: November 2021

Immigrants’ likelihood of mixed union formation differs depending on their country of origin for unclear reasons. Cultural proximity theory suggests that immigrants’ likelihood of mixed union formation depends on the cultural proximity between their country of origin and the receiving country. Opportunity structure theory, on the other hand, suggests that immigrants’ likelihood of mixed union formation depends on their opportunities to find suitable partners from their own national origin group in local partner markets in the destination country. This study uses administrative register data to examine union formation patterns among 1.5 and second-generation immigrants in Denmark. We follow 71,122 1.5 and second-generation immigrants from 120 different national origin groups residing in 11 local partner markets in Denmark from age eighteen until they form their first union or right censoring occurs. Our results using multilevel discrete-time event history analysis suggest that differences in the likelihood of mixed union formation are explained partly by cultural factors, such as religion, language, and degree of globalization, and partly by the opportunity structures in local partner markets, such as group size, sex ratio, and within-group educational similarity. However, cultural proximity explains a much larger proportion of the variation in mixed union formation between national origin groups than opportunity structures do.
Opinia konstytucyjna w sprawie poselskiego projektu ustawy o zasadach wykonywania orzeczeń Europejskiego Trybunału Praw Człowieka (wątki prawnomiędzynarodowe)
Authors: Mik Cezary
Published: November 2021

The author acknowledges the necessity for a comprehensive regulation of the implementation of judgments of the European Court of Human Rights in Polish law. However, he remains critical towards the bill in question. He considers the solutions concerning the concept of implementing judgments to be defective. The author also indicates errors related to the proposed manner of implementing judgments, in particular to the problem of issue of individual and general measures, the so-called just satisfaction, as well as to determining the scope of executive duties of the state.
Możliwość zrzeczenia się alimentów przez uprawnionego
Authors: Tomaszewska Agnieszka
Published: November 2021

The obligation to provide maintenance is created ex lege, regardless of parties’ will. Both the maintenance obligation and the corresponding right to maintenance are strictly personal and inalienable. However, it is possible to conclude a contract between the obligee and the obligor concerning the maintenance obligation.
STUDI EKSPERIMENTAL PENGARUH FREKUENSI GELOMBANG DAN DIAMETER KAWAT GENERATOR DC TERHADAP DAYA BANGKITAN MODEL MEKANISME PLTGL TIPE APUNG
Authors: Ulum Miftahul , Noerpamoengkas Ardi
Published: November 2021

Indonesia adalah negara maritim yang kaya akan sumber daya laut, lautan Indonesia terbentang luas dan memiliki potensi sumber daya energi terbarukan yang mumpuni dalam segi pemanfaatan energi gelombang laut. Dinegara maju sudah banyak pengamplikasian model pembangkit listrik dengan memanfaatkan gelombang laut diantaranya Canada, Portugal dan Amerika utara. Untuk itu pada penelitian ini akan di lakukan pemodelan prototipe mekanisme pembangkit listrik tenaga gelombang laut dengan model mekanisme apung, diharapkan penelitian ini berguna untuk pengembangan model-model alat konversi energi gelombang laut yang dapat diaplikasikan dilautan Indonesia kedepannya. Metode yang akan digunakan adalah metode eksperimen dengan alat bantu kolam prototipe skala laboratorium, dengan variasi yang digunakan pada mekanisme adalah frekuensi gelombang dan diameter kawat pada generator DC. Besar variasi pada gelombang adalah 0.8, 1, dan 1.4 Hz, sedangkan diameter kawat 0.6, 0.7, dan 0.8 mm. Tujuan dari penelitian ini adalah untuk mendapatkan daya bangkitan energi listrik dalam volt. Hasil dari penelitian ini didapat hasil terbesar pada variasi frekuensi gelombang ialah 0.05526 volt pada frekuensi 1.4 Hz. Begitu pula dengan variasi diameter kawat dimana daya tertinggi pada kawat diameter 0.6 mm.
Studi Eksperimental Pengaruh Kecepatan Engkol dan Variasi Diameter Disk terhadap Amplitudo, Frekuensi dan Daya pada Mekanisme Pembangkit Gelombang
Authors: Ulum Miftahul , Noerpamoengkas Ardi , Arifin Ahmad Anas , Firmansyah Hanif Darmawan
Published: November 2021

Kebutuhan akan energi yang terbarukan di Indonesia perlu dikembangkan salah satunya adalah energi  yang berasal dari pembangkit listrik mikrohidro karena dapat meminimalisir penggunaan sumber energi yang berasal dari fosil. Penggunaan gelombang air sebagai seumber energi juga dirasa memiliki dampak resiko yang relatif kecil, serta pemanfaatannya yang mudah diperbarui. Pada penelitian ini akan dilakukan studi eksperimental dengan simulasi pada alat pembuat gelombang air. Studi eksperimental ini menggunakan metode variasi frekuensi kecepatan motor dan jarak engkol terhadap amplitudo dan frekuensi gelombang. Variabel bebas yang digunakan dalam penelitian ini adalah tinggi gelombang atau amplitudo dan panjang gelombang yang dihasilkan. Dengan membuat  prototype  wave  tank  dan  melakukan  pengukuran  dan  perbandingan antara parameter-parameter yang berpengaruh terhadap perhitungan gelombang air yaitu amplitude gelombang (A), periode gelombang (T), dan panjang gelombang (?), kecepatan putaran motor dan diameter poros engkol maka didapatkan parameter apa saja parameter yang saling berpengaruh serta bagaimana variasi kecepatan dan variasi poros engkol berpengaruh terhadap parameter-parameter yang ada. Sehingga dari penelitian ini didapatkan Frekuensi terbesar pada crank nomor 1 dengan kecepatan 120 rpm dengan frekuensi sebesar 2.83 Hz, amplitudo terbesar didapatkan pada crank nomor 3 kecepatan 1 dan 2 dengan amplitudo sebesar 30 mm, dan daya terbesar didapatkan pada crank nomor 3 kecepatan 1 dan 2 dengan energi bangkitan 4.41 watt
Gross regional product: study of influencers
Authors: Karpenko Elena , Rasseko Yuliya
Published: November 2021

The relevance of the research topic is determined by special attention to issues of regional development in the state policy of the Republic of Belarus, the quality of life of 78.6% of the country's population depends on the level of development of the regions under study. The problem of regional development is the growing imbalances in development between the regions of the country and, as a result, undesirable interregional migration flows of the population and a reduction in the demographic potential of a number of territories, as well as the emergence of signs of depression in a number of areas. The analysis of recent publications makes it possible to verify an ongoing interest in the issue, but the drawback of most studies is the disclosure of the issue within one particular region, or the study of the growth of grp due to conventional factors. According to the authors, until the end of the unexplored, the dependence of the gross regional product on indirect, implicit factors remains. Particular attention is drawn to the author's indicators and their place in the GRP growth model. The aim of the study is to establish the influence of unconditional and indirect factors on the magnitude and dynamics of gross regional product, which will provide an opportunity to formalize the dependence of grp on these factors and subsequently apply the built model in practice. The study methods used in the work are comparison, grouping, correlation-regression analysis, econometric modeling, and a systemic approach. Results of work. The present study considers a set of indicators for six regions of the republic of belarus for the period from 2013 to 2019. Using econometric methods of analysis, the authors built a regression model of the dependence of grp per capita on four exogenous variables, analyzed the degree of influence of these variables and the possibility of impact on them by the state. The area of application of the study results is state policy aimed at the sustainable growth of the economies of the regions. Conclusions. In the constructed model of four exogenous variables, the unemployment rate and the rate of life of the population are most significant. However, according to the authors, in order to achieve the desired level of gross regional product, it is necessary to have a comprehensive impact on all variable models, among which, in descending order of importance, the level of unemployment, the rate of life of the population, the amount of industrial production per person employed in the economy, investment in fixed assets.
Comparative analysis of classifications of public procurement
Authors: Hruzky Yuriy
Published: November 2021

Relevance of the research topic. The article is devoted to theoretical and practical aspects of classification of public procurement in Ukraine. Formulation of the problem. The development of a scientifically sound classification of procurement, which would provide a combination of theory and practice of public procurement, allowed for a more accurate assessment of the effectiveness of the use of budget funds. Analysis of recent research and publications. The article provides an overview of current publications on public procurement management, as well as scientific approaches to the classification of public procurement. Selection of unexplored parts of the general problem. The author emphasizes the insufficiency of domestic works on the classification of public procurement, taking into account the latest changes in the legislation of our state. The purpose of the article is to analyze the classification criteria of public procurement, as well as to find ways to improve the classification of public procurement. Research methods: dialectical, analysis and synthesis, empirical, statistical. Work results and conclusions. The article considers the theoretical and practical principles of classification of public procurement, analyzes scientific approaches to the classification of public procurement, identifies the main criteria for the classification of procurement, improved the classification of public procurement. Field of application of results. The obtained results can be used primarily in procurement procedures, as well as in improving the economic policy of the state. Novelty: The proposed classification of public procurement, which corresponds to the modern stage of the formation of the sphere of public procurement, reproduces the structure and organization of procurement activities in Ukraine.
Covid -19 – A Few Words - The Way to Come Out
Authors: Shraddhamayananda Swami
Published: November 2021

There are some anecdotal remedies from time immemorial in our country. The Vedas and Upanishads have been documented and has inspired Manu and Sushrut in culminating medicine into an evolved concept steeped in belief, common faith and evidence based practices. Some herbs, some vegetables, some condiments and certain spices have been the bane of ayurveda and has helped with digestive disorders, hypertension , insomnia and some memory kinetics - which has also propelled us as a nation into an involvement with homeo medicines. All these with the recent advances of technology and medicine can combat the raging pandemic of COVID 19. The role of food - fruits, vegetables and certain dairy products does have different roles to play in gaining over the virus . With tea it has been a century old belief that it holds a key to the immune response of mankind and the Orient stands by this at all times for many many years since mankind first saw the blue moon.
Hereditary disorders of blood coagulation factors amongst Jews!
Authors: Denis Solomons Hilary
Published: November 2021

This is picked up on routine bloods such as partial thromboplastin times. The prothrombin time is usually normal. There is no excess bleeding after trauma. They may however still bleed excessively after surgery. In terms of treatment or therapy the factor XI level must be kept at greater than 30 % with fresh frozen plasma 5-20 ml./kg./ day. The inheritance is autosomal recessive.In Israel the incidence is 8% amongst Ashkenazi Jews. FactorXI deficiency is also known as; Rosenthal Syndrome or Haemophilia C. Sometimes the child may bleed excessively e.g. at circumcision but they do not bleed as severely as haemophiliacs (factor VIII deficiency) and rarely present with haemarthroses. Haemorrhage is usually from mucousal surfaces.
Problems in the Estimation of the Key Parameters using MLE in Lung Cancer Screening
Authors: Wu Dongfeng
Published: November 2021

We have been working in the area of cancer screening modeling for many years. A well-known and frequently used model in cancer screening is the progressive three-state model [1], where all cancer patients are assumed to go through three states: the disease-free state when one is cancer-free or the cancer is in an early stage that no technology can find; the preclinical state when one without symptom but cancer could be detected by screening, and the clinical state when cancer related symptoms show up. There are three key parameters in the model: a) the screening sensitivity, the probability of a positive screening result given that one is in the preclinical state; b) the distribution of sojourn time, which measures the time duration in the preclinical state; and c) the transition density, which measures the time duration in the disease-free state, or the onset age of the preclinical state. These three parameters are called the key parameters since they determines the screening processes and all other terms, for example, lead time (diagnosis time advanced by screening), probability of over-diagnosis, etc., are functions of these three. Therefore accurate estimation of these three key parameters is critical and lays a foundation for all other estimations.
Centrifugal and Centripetal Thinking About the Biopsychosocial Model in Psychiatry
Authors: Tabb Kathryn
Published: November 2021

The biopsychosocial model, which was deeply influential on psychiatry following its introduction by George L. Engel in 1977, has recently made a comeback. Derek Bolton and Grant Gillett have argued that Engel’s original formulation offered a promising general framework for thinking about health and disease, but that this promise requires new empirical and philosophical tools in order to be realized. In particular, Bolton and Gillett offer an original analysis of the ontological relations between Engel’s biological, social, and psychological levels of analysis. I argue that Bolton and Gillett’s updated model, while providing an intriguing new metaphysical framework for medicine, cannot resolve some of the most vexing problems facing psychiatry, which have to do with how to prioritize different sorts of research. These problems are fundamentally ethical, rather than ontological. Without the right prudential motivation, in other words, the unification of psychiatry under a single conceptual framework seems doubtful, no matter how compelling the model. An updated biopsychosocial model should include explicit normative commitments about the aims of medicine that can give guidance about the sorts of causal connections to be prioritized as research and clinical targets.
ANALISIS KEDALAMAN AKUIFER AIR TANAH DENGAN METODE GEOLISTRIK DI DISTRIK SENTANI KOTA KABUPATEN JAYAPURA
Authors: DAMAYANTI BLESKADIT CHATERINE , VIRMAN VIRMAN , SIALLAGAN JOHNSON
Published: November 2021

Geophysical research on geoelectric method configuration schlumburger has been carried out in Sentani Kota area, Jayapura district to analyze the depth of groundwater aquifers. The data consisted of seven points measurement spread in Sentani Kota areas namely Kampung Harapan, Hawaii, Kampung Sereh, Kompleks 751, Pasar Lama, Doyo Baru, and Kampung Toware. The data obtained was done by processing data with IP2WIN software, and then made a subsurface profile likes log. Based on data processing, the results obtained showed that in Kampung Harapan the potential groundwater aquifer was found with a resistivity value of 18 Ωm at a depth of > 17.9 m. In the Hawaiian area potential groundwater aquifers are found with resistivity values of 8.92 Ωm at a depth of 64.7 m. In the Kampung Sereh area potential groundwater aquifers were found with resistivity values of 14 Ωm at a depth of 24 m. In the complex area of 751 a depressed groundwater aquifer is found in two layers with a third layer resistivity value of 106 Ωm at a depth of 13.3 m and a fifth layer 81.8 Ωm at a depth of >28.6 m. In the Pasar Lama area groundwater aquifers were found with resistivity values of 102 Ωm at depths > 17.4 m. In the Doyo Baru area, a potential depressed groundwater aquifer was found with a resistivity value of 50.1 Ωm at a depth of 123 m. And in the Kampung Toware a potential groundwater aquifer is found with a resistivity value of 11.5 Ωm at a depth of >27.7 m. From the results of the study, in the Sentani City area, groundwater aquifers were arranged by lithology of sandstone.
Ordering of Warships for the Brazilian Navy Using the New Method: AHP-Gaussian with Pearson’s Correlation
Authors: Gomes Carlos Francisco Simões , Rodrigues Marcus Vinícius Gonçalves , Costa Igor Pinheiro de Araújo , dos Santos Marcos
Published: November 2021

This paper aims to support the selection decision of a medium-sized warship (between 2,000 and 3,000 tons), to be built in Brazil, presenting the alternatives in a hierarchical manner. Among the various multicriteria decision analysis (MCDA) methods, we used the analytic hierarchy process (AHP) as a basis. Throughout the study, we will propose some adjustments to the AHP in order to make the decision more robust (such as the use of the Gaussian factor and Pearson’s correlation). The criteria were listed and their respective weights were assigned in light of the National Defense Strategy, the Navy’s Strategic Program and interviews carried out with Brazilian navy officers with more than twenty years of career. To list the criteria, we adopted the critical incident technique. The use of the adapted AHP method in choosing the unit to be built can be considered as a transparent way, with a clearly scientific bias, for the Brazilian society to have the perception that the best option was made among the three models of warships presented.
Study on Cross-Basin Ecological Compensation Mechanism and Compensation Standard
Authors: Luo Jinren , Sun Yizhi , Zhao Yihu , Fu Qinyao , Li Jiayin
Published: November 2021

Water resources in China’s river basins are scarce, and the pollution that shrouds them is serious. Constant disputes have emerged between the upstream and downstream sectors due to the contamination of river basins. Moreover, China’s research on ecological compensation mechanisms and compensation standards is still immature at present. Thus, this study establishes a compensation model and introduces the compensation coefficient K, including the compensation coefficient K1 between the upstream and downstream governments and the compensation coefficient K2 between the upstream government and the central government. This paper adopts the Bargain Game Model and obtains the value of K2 through the decision-making process between the central government and the upstream local government. In addition, amendment to the final offer arbitration law is used to acquire the value of K1 by proving the existence and uniqueness of equilibrium. Then, this paper takes the Taohe River Basin as an example and combines the compensation model to analyze, using the simplified compensation function to determine the amount of emission pollution from upstream to downstream and the compensation that upstream should receive.
Soil CEC Predicting Model of Tobacco-Planting Fields in Chenzhou, South Hunan Province
Authors: Xiao Y S , Cao Z H , Li W J , Liao Y H , He B , Li L J , He Z H , Zhong Q
Published: November 2021

Background: Cation exchange capacity (CEC) is a basic but important soil property of soil fertility or quality, CEC predicting model is often derived from other soil properties measured more easily because the traditional method determining CEC is time-consuming and laborious. It is necessary to establish a new CEC prediction model for a new region because CEC predicting model usually is dependent on the study region. Objective: Chenzhou City is the most important and typical tobacco-planting region with tobacco-rice rotation in Hunan province and China, this study was conducted to establish CEC predicting model for the tobacco-planting fields in Chenzhou because so far no CEC predicting model is available for tobacco-planting fields in Chenzhou and in China. Method: In total 1055 topsoil samples (0∼20 cm) were collected in 2015 from the tobacco-planting fields in Chenzhou, soil properties included the particle size composition, pH, soil organic matter and various nutrients were determined, the status of CEC were assessed, and then CEC predicting models were setup in different regions in Chenzhou. Result: The results showed that CEC in Chenzhou was ranged from 3.50 to 48.50 cmol (+) kg-1 with a mean of 22.05 cmol (+) kg-1, averagely belonged to the very high grade (>20 cmol(+) kg-1). There were significant differences in CECs in different regions in Chenzhou, which was the highest in Jiahe (23.83 cmol(+) kg-1) but the lowest in Anren (15.78 cmol(+) kg-1). CEC was significantly correlated with different soil properties in different regions, which was significantly correlated with coarse sands, fine sands, clays, pH and total P in Chenzhou (R= 0.312**∼0.445**), significantly correlated with coarse sands, silts, fine sands, clays, pH, total P, exchangeable Ca2+, Mg2+ and available Zn in Suxian (R= 0.430**∼0.684**), significantly correlated with coarse sands, fine sands, silts, clays, pH, total P, available B and Cu in Yongxing (R=0.321**∼0.605**), significantly correlated with coarse sands, fine sands and clays and total P in Guiyang (R=0.330**∼0.477**), significantly correlated with coarse sands, silts and total K in Yizhang (R=0.326**∼0.466**), and only significantly correlated with fine sands in Jiahe (R=0.350**). The accuracy of CEC predicting model usually was lower when less properties involved. Based on the comparison of the R2 and RMSE of the established CEC predicting models, it is recommended that the total model for Chenzhou could be used for Guiyang, Jiahe and Yizhang, while the regional models should be selected for Yongxing, Anren and Suxian. Conclusion: This study proves further that different soil properties were most important for CEC predicting models in different regions, new CEC predicting models must be setup for a new study region, and soil organic matter is not a variable in soil CEC predicting models for tobacco-planting fields in Chenzhou, which are different from some previous studies.
Employee satisfaction, employee engagement and turnover intention: The moderating role of position level
Authors: Wen Decheng , Yan Dongwei , Sun Xiaojing
Published: November 2021

BACKGROUND:

Employee satisfaction, employee engagement and turnover intention have always been hot issues in the study of sustainable human resource management. Understanding the relationship among the three is critical for both researchers and human resource practitioners.

OBJECTIVE:

This study aims to distinguish the effects of employee satisfaction on employee engagement and turnover intentions, and explore the mediating roles of employee engagement and the moderating effects of position level.

METHODS:

Structural equation modelling and questionnaire.

RESULTS:

Pay satisfaction, satisfaction with supervisor, satisfaction with work itself, and satisfaction with promotion have positive impacts on employee engagement significantly. Pay satisfaction, satisfaction with supervisor, satisfaction with promotion, satisfaction with co-workers have negative impacts on turnover intention. Employee engagement has a negative impact on turnover intention. Employee engagement partially mediates the relationships between satisfaction with supervisor and turnover intention as well as satisfaction with promotion and turnover intention. The moderating roles of position level between satisfaction with supervisor, satisfaction with co-workers and turnover intention have been supported by data.

CONCLUSIONS:

This paper validates the relationship among employee satisfaction, employee engagement and turnover intention, and the moderating role of position level systematically. Some suggestions are provided for practitioners in the area of human resource management.
Formation of bone extracellular matrix in a rotational bioreactor: Preseeding of human mesenchymal stromal cells on a thin polymer scaffold
Authors: Larionov Peter Mikhailovich , Maslov Nikolai Anatolevitch , Ganymedov Vladimir Leonidovitch , Tereshchenko Valeriy Pavlovitch , Samokhin Alexander Gennadevitch , Tsibulskaya Elena Olegovna , Tikhonovich Titov Anatoly
Published: November 2021

BACKGROUND: Periprosthetic osteolysis is known to be the main reason for aseptic instability after the arthroplasty or dental implantation. The use of tissue-engineered scaffolds that allow bone formation area, produced using flow or rotational bioreactor, seems to be a promising approach for such bone lesions treatment. OBJECTIVE: To evaluate the bone neo-extracellular matrix formation within the three-week culture of a scaffold in a coaxial rotational bioreactor generating the preliminary mathematically modelled FSS values with the aim to develop a tissue-engineered scaffold for periprosthetic osteolysis prevention, but reactor critical characteristics like fluid shear stress (FSS) should be fine-tuned to achieve good cell density and prevent cell loss by the scaffold. METHODS: Thin film biodegradable polymer carrier, produced with electrospun and then seeded with hMSCs (human mesenchymal stromal cell) and culture for three weeks in rotational bioreactor, which generates the preliminary math model-calculated FSS from 4 to 8 mPa. Results were assessed with laser scanning confocal microscopy with immunofluorescence, and electron scanning microscopy with spectroscopy. RESULTS: After two weeks of culture, there were no significant differences between the density of hMSC cultured in the static conditions and bioreactor but after 3 weeks the cell density in the bioreactor increased by 35% compared to the static conditions (up to 3.53×106±462 per 1 cm2, P < 0.001). The immunofluorescence intensity exhibited by type I collagen after two and three weeks of culture increased 2.5-fold (48.3±0.39 a.u., P < 0.001) and 1.31-fold (74.0±0.29 a.u., P < 0.001) in the bioreactor, but for osteopontin after 3 weeks of culture in the static conditions was similar to those in the bioreactor. CONCLUSIONS: Optimization of the reactor characteristics with the mathematically modelled FSS values could significantly improve cell proliferation, differentiation, and enhanced formation of the neo-extracellular matrix within 3 weeks in the rotational bioreactor.
Point mutation of COVID-19 proteins: A study on noval corona virus (nCov) correlation with MERS and H1N1 viruses and in silico investigation of nCoV proteins for future applications
Authors: Kaushik Akansha , Kasana Swati , Verma Priyanka , Singh Anuj Kumar
Published: November 2021

Coronavirus disease (COVID 19) which is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) was first reported in Wuhan, China in December 2019. The disease transformed to a pandemic and affected people’s lives all over the world. It caused death to millions of people all over the world. In this project we focused on finding out the correlation of SARS-CoV2 with other respiratory diseases causing viruses like MERS and H1N1 influenza viruses. We further investigated to understand the mutations that occur in the sequences of the SARS-CoV2 during the spread of the disease and correlated it with the functional domains of proteins. The resulted phylogenetic tree indicated that SARS-CoV2 is closely related to the MERS and H1N1 viruses are distantly related. The mutation analysis of 10 different proteins of the SARS-CoV2 shows that there were more than 50 point-mutations among 34 countries sequences for six proteins. Interestingly, four proteins did not any mutation during the analysis. Therefore, these four proteins may be taken into consideration during the development of the diagnostics or therapeutics against this disease.
Role of reactive oxygen species and antioxidants in periodontal disease
Authors: Saluja Harish M. , Sachdeva Shivani , Mani Amit
Published: November 2021

Recent epidemiological studies reveal that more than two-third of the world’s population suffers from one of the chronic forms of periodontal disease. The primary etiological agent of this inflammatory disease is a polymicrobial complex, predominantly Gram negative anaerobic or facultative bacteria within the sub-gingival biofilm. These bacterial species initiate the production of various cytokines such as interleukin-8 and TNF-α, further causing an increase in number and activity of polymorphonucleocytes (PMN) along with these cytokines, PMNs also produce reactive oxygen species (ROS) superoxide via the respiratory burst mechanism as the part of the defence response to infection. ROS just like the interleukins have deleterious effects on tissue cells when produced in excess. To counter the harmful effects of ROS, human body has its own defence mechanisms to eliminate them as soon as they are formed. The aim of this review is to focus on the role of different free radicals, ROS, and antioxidants in the pathophysiology of periodontal tissue destruction.
Ideal ratio mask estimation using supervised DNN approach for target speech signal enhancement
Authors: Selvaraj Poovarasan , Chandra E.
Published: November 2021

The most challenging process in recent Speech Enhancement (SE) systems is to exclude the non-stationary noises and additive white Gaussian noise in real-time applications. Several SE techniques suggested were not successful in real-time scenarios to eliminate noises in the speech signals due to the high utilization of resources. So, a Sliding Window Empirical Mode Decomposition including a Variant of Variational Model Decomposition and Hurst (SWEMD-VVMDH) technique was developed for minimizing the difficulty in real-time applications. But this is the statistical framework that takes a long time for computations. Hence in this article, this SWEMD-VVMDH technique is extended using Deep Neural Network (DNN) that learns the decomposed speech signals via SWEMD-VVMDH efficiently to achieve SE. At first, the noisy speech signals are decomposed into Intrinsic Mode Functions (IMFs) by the SWEMD Hurst (SWEMDH) technique. Then, the Time-Delay Estimation (TDE)-based VVMD was performed on the IMFs to elect the most relevant IMFs according to the Hurst exponent and lessen the low- as well as high-frequency noise elements in the speech signal. For each signal frame, the target features are chosen and fed to the DNN that learns these features to estimate the Ideal Ratio Mask (IRM) in a supervised manner. The abilities of DNN are enhanced for the categories of background noise, and the Signal-to-Noise Ratio (SNR) of the speech signals. Also, the noise category dimension and the SNR dimension are chosen for training and testing manifold DNNs since these are dimensions often taken into account for the SE systems. Further, the IRM in each frequency channel for all noisy signal samples is concatenated to reconstruct the noiseless speech signal. At last, the experimental outcomes exhibit considerable improvement in SE under different categories of noises.
Low illumination image enhancement based on multi-scale CycleGAN with deep residual shrinkage
Authors: Zhou Daxin , Qian Yurong , Ma Yuanyuan , Fan Yingying , Yang Jianeng , Tan Fuxiang
Published: November 2021

Low-illumination image restoration has been widely used in many fields. Aiming at the problem of low resolution and noise amplification in low light environment, this paper applies style transfer of CycleGAN(Cycle-Consistent Generative Adversarial Networks) to low illumination image enhancement. In the design network structure, different convolution kernels are used to extract the features from three paths, and the deep residual shrinkage network is designed to suppress the noise after convolution. The color deviation of the image can be resolved by the identity loss of CycleGAN. In the discriminator, different convolution kernels are used to extract image features from two paths. Compared with the training and testing results of Deep-Retinex network, GLAD network, KinD and other network methods on LOL-dataset and Brightening dataset, CycleGAN based on multi-scale depth residuals contraction proposed in this experiment on LOL-dataset results image quality evaluation indicators PSNR = 24.62, NIQE = 4.9856, SSIM = 0.8628, PSNR = 27.85, NIQE = 4.7652, SSIM = 0.8753. From the visual effect and objective index, it is proved that CycleGAN based on multi-scale depth residual shrinkage has excellent performance in low illumination enhancement, detail recovery and denoising.
Effect of organic additives on storage stability of camel liver catalase against environmental conditions
Authors: Zeyadi Mustafa
Published: November 2021

The storage stability of catalase is very low under practical reaction conditions. Therefore, this study is aimed to evaluate the storage stability of catalase from camel liver by treated it with polyethylene glycol (PEG), glycerol, bovine serum albumin (BSA) and glucose against different storage conditions. The effect of some additives as stabilizers on the storage stability of camel liver catalase at 4°C and 30°C after 30 and 90 days was studied. The enzyme with additives at 5%concentration was more stable at 4 and 30°C for 90 days of incubation than native enzyme. The activity of catalase was more thermal stable in presence of 5%additive. The activity of enzyme with 5%BSA and glucose was retained 60%of its activity at 60°C. At pH 11 the catalase with glucose retained 30%of its activity. The native enzyme lost 80%of its activity in presence of 5 mM β-mercaptoethanol, where the enzyme with additive retained 30–46%of its activity. At 8 M urea, the native enzyme and enzyme with 5%of all additives retained 28%and 61–77%of its activity, respectively. The catalase with additives retained 50–90%of its activity in presence of different dyes. The results appeared that the catalase with additives may be used for elimination of excess of hydrogen peroxide after bleaching of textile.
Quantum processing of cytidine derivatives and evaluating their in silico interactions with the COVID-19 main protease
Authors: Harismah Kun , Hajali Narjes , Mirzaei Mahmoud , Salarrezaei Elham
Published: November 2021

This work was performed by the importance of exploring possible medications for COVID-19 pandemic. In this regard, cytidine (Cyd) derivatives were investigated to reach a point to see their benefit of employing for the purpose. Each of halogenated models of Cyd including CydF, CydCl, CydBr, and CydI were investigated in addition to the original CydH model. Density functional theory (DFT) based quantum processing were performed to obtain stabilized structures in addition to evaluation of frontier molecular orbitals features. Next, molecular docking (MD) simulations were performed to reach a point of formations of interacting ligand-target complexes. Among the investigated models CydH and CydI were working better than other model for reaching the purpose of this work, in which the derived CydI model was indeed the ligand with the highest suitability for formation of ligand-target complexes. As a consequence, such ligands of original and halogenated Cyd models might work for inhibition of main protease (MPro) enzyme of COVID-19 based on the obtained meaningful vales for complex strengths in addition interacting with the amino acids of active site. More precisely, the CydI model could be proposed as promising ligand for showing the inhibitory effects towards the MPro target of COVID-19.
Mauritania’s internal migration dynamics and trends in response to rainfall variability and change1
Authors: El Vilaly Mohamed Abd Salam M. , Jones Maureen , Tankari Mahamadou R. , Mahe Gil , Juran Sabrina
Published: November 2021

The northwest African country of Mauritania is a vast, desert territory, which was historically been dominated by pastoral nomads. Since independence in 1960, the country has witnessed a dramatic sedentarization of its nomadic population, as well as settlements in and movements to urban centers. This vast sedentarization movement coupled with internal and interregional migration has resulted in the growth of Mauritania’s urban population from less than 10 percent of the total population in 1965 to nearly 90 percent in 2013. Factors that have caused this rapid urbanization, include the droughts that spanned the late 1960s through to the early 1980s, and the turbulent transformation of Mauritania’s political economy. The aim of this study is to determine and examine internal migration flows to analyze the relationship between long-term rainfall changes and dynamic spatial demographic shifts in terms of movements toward urban centers. In this regard, we propose an assessment approach that integrates official statistics from the decennial census and rainfall data, with available socioeconomic variables, to characterize interregional migration flows. Our result confirms that rates of interregional migration remain elevated and are expected to increase. In 2013, 702,575 individuals were documented as having participated in interregional migration, comprising 17.5 percent of the total population. In comparison, there were 477,814 individuals, which migrated inter-regionally in 2000, and 208,039 in 1988. These results demonstrate distinct interactions between climate variability and interregional migration in Mauritania throughout the past four decades.
Big Data adoption in official statistics in Kenya: Challenges, opportunities and determinants
Authors: Moturi Christopher A. , Wairimu Allan Gathuru
Published: November 2021

The data revolution has increased data demands for leveraging on Big Data in the production of statistics. The paper assesses the adoption of Big Data in research institutes in Kenya. Data were collected from 64 data practitioners based in the 24 research institutes that have a mandate to produce and analyse official statistics. The paper establishes the risks and challenges of using Big Data in statistics, identifies the determinants of adoption of Big Data in statistics and validates the relevance of a Technology Adoption Model (TAM) for predicting the adoption. It is the conclusion that there are immense opportunities for Big Data in statistics if the associated risks and challenges are addressed and the identified key determinants prioritized to promote the adoption.
Central perforated VRAM flap and neurostimulated levator augmentation for functional and aesthetical reconstruction after abdominoperineal excision in cancer
Authors: Bernuth Silvia , Jakubietz Michael , Isbert Christoph , Reibetanz Joachim , Meffert Rainer , Jakubietz Rafael , Schmidt Karsten
Published: November 2021

BACKGROUND: Preservation of quality of life regarding fecal continence after abdominoperineal excision (APE) in cancer is challenging. Simultaneous soft tissue coverage and restoration of continence mechanism can be provided through an interdisciplinary collaboration of colorectal and plastic reconstructive surgery. OBJECTIVE: Evaluation of surgical procedure and outcome combining soft tissue reconstruction using a central perforated vertical rectus abdominis myocutaneous flap (VRAM), implementing a perineostoma and restoring anorectal angle augmenting the levator ani by neurostimulated graciloplasty. METHODS: 14 Patients underwent APE due to cancer. In all patients coverage was achieved by pedicled VRAM and simultaneous pull-through descendostomy (perineostoma). 10 of those patients received a levator augmentation additionally. Postoperative complications, functional measures of continence as well as quality of life were obtained. RESULTS: Perineal minor complication rate was 43% without need of surgical intervention. All but one VRAM survived. Continence measures and disease specific life quality showed a good preservation of continence in most patients. CONCLUSION: The results present a complex therapy option accomplished by a collaboration of two highly specialized partners (visceral and plastic surgery) after total loss of the sphincter function and consecutive fecal insufficiency after APE.
Use of bean grain-based mixtures in the baking industry
Authors:   All-Russian Scientific and Research Institute for Grain and Products of its Processing – Branch of V.M. Gorbatov Federal Research Center for Food Systems of RAS, Zverev S.V. , Bondarenko Yu.V. ,   K.G. Razumovsky Moscow State University of technologies and management (the First Cossack University), Glukhova E.V. ,   K.G. Razumovsky Moscow State University of technologies and management (the First Cossack University)
Published: November 2021

The article presents the results of research aimed at the development of flour mixtures. The interval of variation of the addition of flour from leguminous crops was estimated. According to a specially developed program, the values of the addition of flour from leguminous grain to traditional baking flour were obtained. The intervals of variation of these additives, in which the mixture has a complete protein, have been revealed.
Technical solutions for intensification dough kneading and improving bread quality
Authors:   Saratov State Agrarian University named after N. I. Vavilov, Dem’yanyuk A.V. , Sadygova M.K. ,   Saratov State Agrarian University named after N. I. Vavilov, Rustemova A.Zh. ,   Kazakh National Agrarian University, Yanitsyna Yu.Yu. ,   JSC "Tsel`"
Published: November 2021

The article presents the results of the development of a pilot model of a kneading machine with a volumetric-inertial working body and studies its influence on the quality of semi-finished products, finished products made of wheat and rye flour. Rational and optimal parameters of the dough kneading process are obtained due to the peculiarities of the biochemical and colloidal processes in wheat and rye dough. The efficiency of the design of the spherical tips of the kneading blades of the volumetric – inertial working body is proved, which allows for kneading up to 0.95 of the diameter of the inner surface of the bowl, while taking into account that S of the surface of the sphere is greater than S of the projection on the walls of the bowl.