bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of β-Adrenergic Blockade on Metabolic and Inflammatory Responses in a Rat Model of Ischemic Stroke
Authors: Lin Shih-Yi , Wang Ya-Yu , Chang Cheng-Yi , Wu Chih-Cheng , Chen Wen-Ying , Kuan Yu-Hsiang , Liao Su-Lan , Chen Chun-Jung
Published: June 2020

Ischemic stroke provokes an inflammatory response concurrent with both sympathetic nervous system activation and hyperglycemia. Currently, their crosstalk and consequences in stroke outcomes are of clinical attraction. We have provided experimental evidence showing the suppressive effects of the nonselective β-adrenoreceptor antagonist propranolol on hyperglycemia, inflammation, and brain injury in a rat model experiencing cerebral ischemia. Pretreatment with propranolol protected against postischemic brain infarction, edema, and apoptosis. The neuroprotection caused by propranolol was accompanied by a reduction in fasting glucose, fasting insulin, glucose tolerance impairment, plasma C-reactive protein, plasma free fatty acids, plasma corticosterone, brain oxidative stress, and brain inflammation. Pretreatment with insulin alleviated—while glucose augmented—postischemic brain injury and inflammation. Additionally, the impairment of insulin signaling in the gastrocnemius muscles was noted in rats with cerebral ischemia, with propranolol improving the impairment by reducing oxidative stress and tumor necrosis factor-α signaling. The anti-inflammatory effects of propranolol were further demonstrated in isoproterenol-stimulated BV2 and RAW264.7 cells through its ability to decrease cytokine production. Despite their potential benefits, stroke-associated hyperglycemia and inflammation are commonly linked with harmful consequences. Our findings provide new insight into the anti-inflammatory, neuroprotective, and hypoglycemic mechanisms of propranolol in combating neurodegenerative diseases, such as stroke.
PD-1: Its Discovery, Involvement in Cancer Immunotherapy, and Beyond
Authors: Ishida Yasumasa
Published: June 2020

On December 10, 2018, I was sitting among the big crowd of audience, as one of the invited guests to the ceremony, in the Stockholm Concert Hall. When King of Sweden Carl XVI Gustaf bestowed the diploma and medal of Nobel Prize of Physiology or Medicine 2018 on Dr. Tasuku Honjo and shook his hand for a while, surrounded by the thunderous applause and energetically blessing orchestral music, I thought that it had been a long journey for the molecule that we had first isolated in the early 1990s. Although it was truly a commemorable moment in the history of the programmed death-1 (PD-1) research, I believe we still have a long way to go. In this review article, I will explain why I think so, particularly by focusing on the potential role(s) that PD-1 appears to play in self-nonself discrimination by the immune system.
Comparison of Multiscale Imaging Methods for Brain Research
Authors: Tröger Jessica , Hoischen Christian , Perner Birgit , Monajembashi Shamci , Barbotin Aurélien , Löschberger Anna , Eggeling Christian , Kessels Michael M. , Qualmann Britta , Hemmerich Peter
Published: June 2020

A major challenge in neuroscience is how to study structural alterations in the brain. Even small changes in synaptic composition could have severe outcomes for body functions. Many neuropathological diseases are attributable to disorganization of particular synaptic proteins. Yet, to detect and comprehensively describe and evaluate such often rather subtle deviations from the normal physiological status in a detailed and quantitative manner is very challenging. Here, we have compared side-by-side several commercially available light microscopes for their suitability in visualizing synaptic components in larger parts of the brain at low resolution, at extended resolution as well as at super-resolution. Microscopic technologies included stereo, widefield, deconvolution, confocal, and super-resolution set-ups. We also analyzed the impact of adaptive optics, a motorized objective correction collar and CUDA graphics card technology on imaging quality and acquisition speed. Our observations evaluate a basic set of techniques, which allow for multi-color brain imaging from centimeter to nanometer scales. The comparative multi-modal strategy we established can be used as a guide for researchers to select the most appropriate light microscopy method in addressing specific questions in brain research, and we also give insights into recent developments such as optical aberration corrections.
Urban Particulate Matter Enhances ROS/IL-6/COX-II Production by Inhibiting MicroRNA-137 in Synovial Fibroblast of Rheumatoid Arthritis
Authors: Tsai Ming-Horng , Chi Miao-Ching , Hsu Jen-Fu , Lee I-Ta , Lin Ko-Ming , Fang Mei-Ling , Lee Ming-Hsueh , Lee Chiang-Wen , Liu Ju-Fang
Published: June 2020

Background: Rheumatoid arthritis (RA) has been associated with air pollution, possibly due to the augmentation of inflammatory effects. In this study, we aimed to determine the roles of inflammatory pathways and microRNA involved in the pathogenesis of RA fibroblast-like synoviocytes (FLS) inflammation induced by particulate matter. Methods: The inflammatory mediators, messenger RNAs, microRNAs and their interrelationships were investigated using western blotting, QPCR, ELISA and immunohistochemistry. Results: Particulate matter (PMs) induced an increase in the expression of interleukin-6 (IL-6) and cyclooxygenase-II (COX-II) in RA-FLS and microRNA-137 was found definitely to mediate the inflammatory pathways. PMs-induced generation of reactive oxygen species (ROS) in RA-FLS was attenuated by pretreatment with antioxidants. Nox-dependent ROS generation led to phosphorylation of ERK1/2, p38 and JNK, followed by downregulation of microRNA-137. In vivo studies, the joints of rats exposed to PMs revealed synovial fibroblast inflammation under pathologic examination and the expressions of IL-6 and COX-II were obviously increased. PMs exposure results in activated ROS-mediated mitogen-activated protein kinase (MAPK) signaling pathways and cause increased IL-6 and COX-II through downregulation of hsa-miRNA-137, which lead to inflammation and RA exacerbation. Conclusions: microRNA-137 plays an important role in PMs-induced RA acute exacerbation through MAPK signaling pathways and IL-6/COX-II activation. Targeting these mechanisms can potentially be used to develop new therapeutic strategies and prevention of RA inflammation in the future.
Analysis of the Spatio-Temporal Variability of Precipitation and Drought Intensity in an Arid Catchment in South Africa
Authors: Mengistu Achamyeleh G. , Tesfuhuney Weldemichael A. , Woyessa Yali E. , van Rensburg Leon D.
Published: June 2020

Water deficit is high and precipitation varies spatio-temporally in arid areas. This study was conducted to analyse the spatio-temporal variability of precipitation and drought intensity in an arid catchment in South Africa. The Soil and Water Assessment Tool (SWAT) was used to estimate the spatio-temporal precipitation where nine meteorological stations were used as input to the model. The model was calibrated and validated by regionalization with a physical similarity approach. SWAT only predicts precipitation at sub-basin level. Hence, the mean precipitation was further interpolated by using the inverse distance weighted method (IDW). The Mann–Kendall trend test shows that there was no trend in annual precipitation whereas in the monthly precipitation there was a 0.01 mm decrease. Daily precipitation varied from 0.1 to 4 mm whereas in a monthly basis, it varied from 6 mm (September) to 43.4 mm (February). The annual precipitation varied from 169 mm (1983) to 415 mm (2003) with a long-term mean of 280.8 mm. Precipitation is also highly variable in space throughout the catchment. Generally, annual precipitation decreased from north to south; however, during the winter season, the reverse was true due to the influence of rain-bearing condition from the south- western direction. Based on the aridity index (AI), the catchment is categorized as arid. The SPI shows that the 1983 drought was the worst whereas the 2003 and 2004 years were relatively wet. The results from this study provide baseline information for further research in climate change adaptation and environmental monitoring programs in the region.
Effect of SiC/Fly Ash Reinforcement on Surface Properties of Aluminum 7075 Hybrid Composites
Authors: Patil Namdev Ashok , Pedapati Srinivasa Rao , Mamat Othman Bin , Hidayat Syah Lubis Abdul Munir
Published: June 2020

Friction stir processing (FSP) has emerged as a valuable technique in the surface metal matrix composite fabrication field. In this process, solid-state processing mostly avoids the formation of detrimental phases inside composites. Despite having a high specific strength, further extensive Al alloy applications are limited due to their poor surface properties. A hybrid reinforcement approach can be used to improve surface properties. In this study, industrial waste fly ash material is mixed with hard SiC ceramic particles. The main focus of this research is to improve wear resistance under dry sliding conditions and microhardness of aluminum 7075-T651 by dispersion of silicon carbide-fly ash (SiC/fly ash) powder in a base alloy by FSP. The parameters used for this investigation are: tool rotation rpm (500, 1000 and 1500), the tool traverse mm/min (20, 30 and 40), the reinforcement’s hybrid ratio HR (60:40, 75:25 and 90:10) and the volume percentage vol.% (4%, 8% and 12%). The influence of these parameters on the resultant composite’s microstructure, dry sliding wear rate and micro-hardness was studied. By using response surface methodology (RSM), desirable ranges of process parameters for lower wear rate and higher microhardness were obtained. The interaction effect of SiC/fly ash volume percentage and hybrid ratio had the most influential effect on the wear rates, as well as microhardness of composites. Moreover, microhardness increased with an increase in the volume percentage of SiC/fly ash powders towards high SiC content in hybrid ratio. Interestingly, among stirring parameters, tool traverse speed was found to be more influential than tool rotational speed. The minimum wear rate was observed for the Run 20 sample (w: 1000 rpm, v: 40 mm/min, HR: 75:25, vol.%: 8). A maximum microhardness of 241.20 HV was achieved for Run 15 (w: 500 rpm, v: 40 mm/min, HR: 90:10, vol.%: 12) sample. Mainly, reinforcement distribution—in accordance with the stirring action generated by the tool—had a major role in controlling the surface properties of the resultant composites.
Ternary Aluminides of a New Homologous Series—CePt2Al2 and CePt3Al3: Crystal Structures and Thermal Properties
Authors: Murashova Elena , Morozova Yuliya , Dunaev Sergey , Kurenbaeva Zhanafiya , Tursina Anna
Published: June 2020

In the process of studying the Ce–Pt–Al system, we identified CePt2Al2 and CePt3Al3, two new ternary intermetallic compounds. CePt2Al2 aluminide undergoes a structural phase transition from a low-temperature orthorhombic modification (of its own structure type, Cmme, a = 5.84138(2) Å, b = 6.39099(3) Å, c = 10.11611(5) Å) to a high-temperature tetragonal modification (CaBe2Ge2 type, P4/nmm, a = 4.3637(9) Å, c = 10.0925(14) Å) at 280(1) °C. CePt3Al3 crystallizes with a new type of structure (Cmme, a = 6.36548(6) Å, b = 5.78301(6) Å, c = 13.36245(19) Å) built of structural units of low-temperature orthorhombic CePt2Al2-type and CsCl-type.
Quaternary Misfit Compounds—A Concise Review
Authors: Aliev Sokhrab B. , Tenne Reshef
Published: June 2020

Misfit layered compounds (MLCs) have been studied in the literature for the last 40 years. They are generally made of an alternating sequence of two monolayers, a distorted rocksalt structure, and a hexagonal layered compound. In a typical MLC, the c-axis is common to the two monolayers and so is one of the axes in the layer plan. However, the two compounds are non-commensurate along at least one axis, and the ratio between the two axes is an irrational number making the MLC a non-stoichiometric compound. The two main families of MLC are those based on metal dichalcogenides and CoO2 as the hexagonal layered compound. Traditionally, ternary MLCs were prepared and studied, but some quaternary and multinary MLC minerals have been known for many years. Over the last few years, interest in MLCs with four and even larger number of atoms has grown. Doping or alloying of a ternary MLC permits precise control of the charge carrier density and hence the electrical, thermoelectric, catalytic, and optical properties of such compounds. In this short review, some of these developments will be discussed with the main emphasis put on quaternary MLC nanotubes belonging to the chalcogenide series. The synthesis, structural characterization, and some of their properties are considered. Some recent developments in quaternary cobaltite MLCs and recent studies on exfoliated MLCs are discussed as well.
Phenotypically Induced Intraspecific Variation in the Morphological Development of Wetland and Stream Galaxias gollumoides McDowall and Chadderton
Authors: Dunn Nicholas R. , O’Brien Leanne K. , Closs Gerard P.
Published: June 2020

The hypothesis that contrasting hydrology induces divergent intraspecific phenotypic plastic responses in non-migratory freshwater fish was investigated. Morphologies of wetland and stream Galaxias gollumoides from South Island, New Zealand, at different stages of ontogeny, were examined. Phenotypic responses were tested for in a 2 × 2 factorial laboratory based controlled reciprocal transplant experiment with flow (current or no current) and source habitat (wetland or stream), as treatments. There was a shift in the overall head morphology of wetland current treatment G. gollumoides away from the wetland no current treatment, and toward the stream current treatment, demonstrating convergence in head morphology in the presence of flow of wetland and stream sourced captive G. gollumoides. Morphologies of captive reared G. gollumoides were also compared to developmental trajectories of morphological characters during the ontogeny of field reared first year, and adult conspecifics. In combination, experimental and field results support the hypothesis, finding habitat hydrology to be the potential mechanism inducing and maintaining intraspecific morphological divergence in G. gollumoides. Recognition of this mechanism inducing morphological divergence between populations also aids the taxonomic description of long genetically recognised lineages of co-members of the Galaxias vulgaris species complex.
Development of Stiffness Measurement Program Using Color Mapping in Shear Wave Elastography
Authors: Lee Haneul , Kim Kyuseok , Lee Youngjin
Published: June 2020

Shear wave elastography with ultrasound is a noninvasive method used for measuring stiffness in the human body. Shear wave elastography can be used for accurately and quantitatively measuring stiffness. However, its disadvantage is that the stiffness value can vary significantly because the region of interest (ROI) setting depends on the diagnostic operator. In this study, a stiffness measurement program using color mapping in shear wave elastography was developed to address the above-mentioned disadvantage. Color map and color ratios were obtained and evaluated for major lower limb muscles (i.e., biceps femoris, medial gastrocnemius, rectus femoris, and tibialis anterior) at active voluntary contraction. According to the result, when the developed program was used, a small standard deviation compared to the conventional stiffness measurement method, such as kilopascal or meter per second unit using ROIs, was measured in all cases. In conclusion, our results demonstrate that the stiffness measurement method using our program is expected to improve reliability in shear wave elastography ultrasound imaging.
Empirical Measurement of Competition in the Thai Banking Industry
Authors: Prayoonrattana Jirawan , Laosuthi Thanarak , Chaivichayachat Bundit
Published: June 2020

The degree of competition in the banking industry can be observed and measured by two approaches, structural and nonstructural. Based on these two approaches, there are various indicators, which are different factors and methods. This paper aims to provide calculations, determine a good indicator, and assess the competitive environment of the Thai banking industry. Specifically, there are four indicators—concentration ratio, Herfindahl–Hirschman Index, Lerner Index, and Panzar–Rosse H statistic—which are widely used to examine the efficiency and effectiveness of policies in the banking industry. The findings indicate that the Lerner Index, calculated by stochastic frontier analysis, is the most reliable indicator of the banking competition environment in Thailand. It has a range of 0.36 to 0.60 and an average value of 0.40. Furthermore, during the period of study, the degree of Thai banking competition had a tendency to increase over time, which reflects an increase in allocative efficiency of resources in the banking industry. This is in accordance with the Financial Sector Master Plan of the country. However, this result probably leads to instability of the financial system. Therefore, policy-makers should carefully regulate competition policy by considering the systematic risk of the banking system at the same time.
Optical Transmission of an Analog TV-Signal Coded at 2.24 GHz and Its Distribution by Using a Radiating Cable
Authors: Correa-Mena Ana Gabriela , Seseña-Osorio Jorge Alberto , Diago-Mosquera Melissa Eugenia , Aragón-Zavala Alejandro , Zaldívar-Huerta Ignacio Enrique
Published: June 2020

In this work, an alternative technology to extend wireless coverage beyond the conventional methods of providing radio propagation coverage is presented. The use of a radiating cable is proposed for difficult-to-reach areas. In this regard, an indoor radiating cable is successfully employed for the distribution of an analog electric signal in a fiber-radio scheme using a microwave photonic filter. A filtered microwave band-pass window located at 2.24 GHz is used as an electrical carrier to transmit an analog TV-signal of 67.25 MHz over an optical link of 25.28 km. Measurements are carried out in an indoor environment. Experimental results demonstrate that the recovered signal is of good quality in each measurement location, exhibiting on average a signal-to-noise-ratio (SNR) of around 31.60 dB.
Smartphone-Based Evaluation of Postural Stability in Parkinson’s Disease Patients During Quiet Stance
Authors: Borzì Luigi , Fornara Silvia , Amato Federica , Olmo Gabriella , Artusi Carlo Alberto , Lopiano Leonardo
Published: June 2020

Background: Postural instability is one of the most troublesome motor symptoms of Parkinson’s Disease (PD). It impairs patients’ quality of life and results in high risk of falls. The aim of this study is to provide a reliable tool for the automated assessment of postural instability. Methods: Data acquisition was performed on 42 PD patients and 7 young healthy subjects. They were asked to keep a quiet stance position for at least 30 s while wearing a waist-mounted smartphone. A total number of 414 features was extracted from both time and frequency domain, selected based on Pearson’s correlation, and fed to an optimized Support Vector Machine. Results: The implemented model was able to differentiate patients with mild postural instability from those with severe postural instability and from healthy controls, with 100% accuracy. Conclusion: This study demonstrated the feasibility of using inertial sensors embedded in commercial smartphones and proposed a simple protocol for accurate postural instability scoring. This tool can be used for early detection of PD motor signs, disease follow-up and fall prevention.
Energy Multiphase Model for Biocoal Conversion Systems by Means of a Nodal Network
Authors: Paredes-Sánchez Beatriz M. , Paredes-Sánchez José P. , García-Nieto Paulino J.
Published: June 2020

The coal-producing territories in the world are facing the production of renewable energy in their thermal systems. The production of biocoal has emerged as one of the most promising thermo-energetic conversion technologies, intended as an alternative fuel to coal. The aim of this research is to assess how the model of biomass to biocoal conversion in mining areas is applied for thermal systems engineering. The Central Asturian Coal Basin (CACB; Spain) is the study area. The methodology used allows for the analysis of the resource as well as the thermo-energetic conversion and the management of the bioenergy throughout the different phases in a process of analytical hierarchy. This is carried out using a multiphase mathematical algorithm based on the availability of resources, the thermo-energetic conversion, and the energy management in the area of study. Based on the working conditions, this research highlights the potential of forest biomass as a raw material for biocoal production as well as for electrical and thermal purposes. The selected node operates through the bioenergy-match mode, which has yielded outputs of 23 MWe and 172 MWth, respectively.
Biorefining of Pigeon Pea: Residue Conversion by Pyrolysis
Authors: Rowena C. Tanquilut Mari , Genuino Homer C. , Wilbers Erwin , Amongo Rossana Marie C. , Suministrado Delfin C. , Yaptenco Kevin F. , Elauria Marilyn M. , Elauria Jessie C. , Heeres Hero J.
Published: June 2020

Pyrolysis is an important technology to convert lignocellulosic biomass to a renewable liquid energy carrier known as pyrolysis oil or bio-oil. Herein we report the pyrolysis of pigeon pea wood, a widely available biomass in the Philippines, in a semi-continuous reactor at gram scale. The effects of process conditions such as temperature (400–600 °C), nitrogen flow rate (7–15 mL min−1) and particle size of the biomass feed (0.5–1.3 mm) on the product yields were determined. A Box-Behnken three-level, three-factor fractional factorial design was carried out to establish process-product yield relations. Of particular interest is the liquid product (bio-oil), of which the yield was shown to depend on all independent variables in a complex manner. The optimal conditions for highest bio-oil yield (54 wt.% on dry feed intake) were a temperature of 466 °C, a nitrogen flow rate of 14 mL min−1 and a particle size of 1.3 mm. Validation of the optimized conditions proved that the average (n = 3) experimental bio-oil yield (52 wt.%) is in good agreement with the predicted value from the model. The properties of product oils were determined using various analytical techniques including gas chromatography-mass spectrometry (GC–MS), gel-permeation chromatography (GPC), nuclear magnetic resonance spectroscopy (13C- and HSQC-NMR) and elemental and proximate analyses. The bio-oils were shown to have low ash content (0.2%), high heating value (29 MJ kg−1) and contain high value-added phenolics compounds (41%, GC peak area) as well as low molecular weight aldehydes and carboxylic acids. GPC analysis indicated the presence of a considerable amount of higher molecular weight compounds. NMR measurements showed that a large proportion of bio-oil contains aliphatic carbons (~60%), likely formed from the decomposition of (hemi)cellulose components, which are abundantly present in the starting pigeon pea wood. Subsequent preliminary scale-up pyrolysis experiments in a fluidized bed reactor (~100 gfeed h−1, 475 °C and N2 flow rate of 1.5 L min−1) gave a non-optimized bio-oil yield of 44 wt.%. Further fractionation and/or processing are required to upgrade these bio-oils to biofuels and biobased chemicals.
Potentiality of Waste-to-Energy Sector Coupling in the MENA Region: Jordan as a Case Study
Authors: Thabit Qahtan , Nassour Abdallah , Nelles Michael
Published: June 2020

Population growth, urbanization, and changes in lifestyle have led to an increase in waste generation quantities. The waste management system in the Middle East and North Africa (MENA) region is still considered an adolescent system, while developed countries have made great progress in this field, including regulation, financing, administration, separation at source, recycling, and converting waste to energy. At the same time, in the MENA region, the best performance of the recycling process is around 7–10% of total waste. Nowadays, many developed countries like Germany are shifting from waste management to material flow systems, which represent the core of a circular economy. Also, it should be stated here that all countries that have a robust and integrated waste management system include waste-to-energy (W-to-E) incineration plants in their solutions for dealing with residual waste, which is still generated after passing through the entire treatment cycle (hierarchy). Therefore, this paper illustrates the potentiality of embedding waste incineration plants in the MENA region, especially in large cities, and addressing the economic and financial issues for the municipalities. Cities in these countries would like to build and operate waste treatment plants; however, municipalities do not have the sustainable investment and operating costs. The solution is to maximize the income from the output, such as energy, recycling materials, etc. In addition, the MENA region is facing another dilemma, which is water scarcity due to climate change, increasing evaporation, and reduction of precipitation. This research illustrates a simulated model for a waste incineration plant in the MENA region. The EBSILON 13.2 software package was used to achieve this process. Furthermore, the simulated plant applies the concept of waste-to-energy-to-water, so that not only is waste converted to energy but, by efficient usage of multi-stage flash (MSF) technology, this system is able to generate 23 MWe of electric power and 8500 m3/day of potable water. A cost analysis was also implemented to calculate the cost of thermal treatment of each ton of municipal solid waste (MSW) during the life span of the plant. It was found that the average cost of treatment over 30 years would be around US$39/ton.
A Fuzzy-PID Scheme for Low Speed Control of a Vehicle While Going on a Downhill Road
Authors: Jin Liqiang , Zhang Ronglin , Tang Binghao , Guo Hao
Published: June 2020

We explored a vehicle hill descent control (HDC) system based on an electronic stability program (ESP) and applied this system to brake cars. The experimental results reveal that our system can effectively reduce the workload of a driver during a downhill journey. In the first phase of our work, the control strategy of the HDC system based on fuzzy-PID (Proportion Integral Differential) was built by MATLAB/Simulink. Then, the co-simulation based on MATLAB/Simulink, CarSim and AMESim was carried out. Finally, a real vehicle test was conducted to further verify the feasibility of the strategy. A series of simulation experiments and real vehicle tests show that the HDC system can assist the driver to control the vehicle while driving downhill at low speed, thus effectively improving the safety of the vehicle and reducing the workload of driver.
Hydrogen Fuel Cell and Ultracapacitor Based Electric Power System Sliding Mode Control: Electric Vehicle Application
Authors: Shtessel Yuri B. , Ghanes Malek , Ashok Roshini S.
Published: June 2020

Control of a perturbed electric power system comprised of a hydrogen fuel cell (HFC), boost and boost/buck DC–DC power converters, and the ultra-capacitor (UC) is considered within an electric vehicle application. A relative degree approach was applied to control the servomotor speed, which is the main controllable load of the electric car. This control is achieved in the presence of the torque disturbances via directly controlling the armature voltage. The direct voltage control was accomplished by controlling the HFC voltage and the UC current in the presence of the model uncertainties. Controlling the HFC and UC current based on the power balance approach eliminated the non-minimum phase property of the DC–DC boost converter. Conventional first order sliding mode controllers (1-SMC) were employed to control the output voltage of the DC–DC boost power converter and the load current of the UC. The current in HFC and the servomotor speed were controlled by the adaptive-gain second order SMC (2-ASMC). The efficiency and robustness of the HFC/UC-based electric power systems controlled by 1-SMC and 2-ASMC were confirmed on a case study of electric car speed control via computer simulations.
Coordinated Control of Active and Reactive Power Compensation for Voltage Regulation with Enhanced Disturbance Rejection Using Repetitive Vector-Control
Authors: Zimann Felipe J. , Stangler Eduardo V. , Neves Francisco A. S. , Batschauer Alessandro L. , Mezaroba Marcello
Published: June 2020

Voltage profile is one of many aspects that affect power quality in low-voltage distribution feeders. Weak grids have a typically high line impedance which results in remarkable voltage drops. Distribution grids generally have a high R/X ratio, which makes voltage regulation with reactive power compensation less effective than in high-voltage grids. Moreover, these networks are more susceptible to unbalance and harmonic voltage disturbances. This paper proposes an enhanced coordinated control of active and reactive power injected in a distribution grid for voltage regulation. Voltage drop mitigation was evaluated with power injection based on local features, such loads and disturbances of each connection. In order to ensure disturbances rejection like harmonic components in the grid voltages, a repetitive vector-control scheme was used. The injection of coordinated active and reactive power with the proposed control algorithm was verified through simulations and experiments, demonstrating that it is a promising alternative for voltage regulation in weak and low-voltage networks subject to inherent harmonic distortion.
Effects of Different Bamboo Forest Spaces on Psychophysiological Stress and Spatial Scale Evaluation
Authors: Lin Wei , Chen Qibing , Zhang Xiaoxia , Tao Jinying , Liu Zongfang , Lyu Bingyang , Li Nian , Li Di , Zeng Chengcheng
Published: June 2020

Forests are large-scale green space resources that may exert a positive impact on human physiology and psychology. Forests can be divided into mixed forest and pure forest, according to the number of dominant tree species. Pure forest offers specific advantages for the study of spatial structure and scale. In this study, a type of pure forest (i.e., bamboo forest) was adopted as a research object to investigate differences in the physiological and psychological responses of psychologically pressured college students to different types of forest space. We recruited 60 participants and randomly assigned them to three experimental groups: forest interior space (FIS), forest external space (FES) and forest path space (FPS). All participants were asked to perform the same pre-test task but different post-test tasks. The pre-test involved performing a pressure-inducing task, whereas the post-test involved viewing photographs of each space type. The same indicators were measured in both the pre- and post-test, including a β/α index from each lobe, positive emotion, negative emotion and total mood disturbance (TMD) values, according to the profile of mood states (POMS), in addition to spatial scale preferences obtained through a questionnaire and interviews. We analysed brain waves and mood indicators through analysis of covariance (ANCOVA), whereby the FES group exhibited the best physiological and psychological relaxation effect. The FPS group displayed a medium effect, and the FIS group exhibited the worst effect. Analysis of variance (ANOVA) was used to analyse the spatial scale scores. The FPS and FES types achieved a higher spatial scale preference scores than the FIS type. Based on a comparison of the psychophysiological results with the spatial scale preference results, spatial structure and scale are considered to be important intrinsic factors that influence the health effects of pure forest. The results can provide guidance for forest-related human health activities and their management.
Lessons from the Frontline: Exploring How Stakeholders May Respond to Emerald Ash Borer Management in Europe
Authors: Marzano Mariella , Hall Clare , Dandy Norman , LeBlanc Fisher Cherie , Diss-Torrance Andrea , Haight Robert G.
Published: June 2020

The emerald ash borer (EAB) has caused extensive damage and high mortality to native ash trees (Fraxinus; sp.) in North America. As European countries battle with the deadly pathogen Hymenoscyphus fraxineus (ash dieback) affecting European ash (Fraxinus excelsior), there is concern that the arrival of EAB will signal the demise of this much-loved tree. While Europe prepares for EAB it is vital that we understand the social dimensions that will likely influence the social acceptability of potential management measures, and experiences from the USA can potentially guide this. We draw on differing sources including a literature review, documentary analysis, and consultation with key informants from Chicago and the Twin Cities of Minneapolis and St. Paul. In this paper, we focus on EAB management responses that involve chemical applications, tree felling and replanting, and biological control, and assess their likely social acceptability to stakeholders based on the perceived risks and benefits. Benefits involve protecting specific ash trees and slowing the spread of EAB across the landscape. Risks include collateral harm from insecticide use on human and environmental health, financial costs and liabilities, and the effectiveness of each approach. Biological control and replacing ash with other species are likely to be largely acceptable across contexts and stakeholder groups but pre-emptive felling and insecticide application could be more problematic if seeking widespread social acceptance. Based on our observations from the evidence collected we offer suggestions for approaching EAB management in Europe with a focus on improving prospects of social acceptability. Strong engagement will be necessary to establish the relevance and reason for using different management approaches and to build awareness and trust.
Canopy Opening and Site Preparation Effects on Conifer and Understory Establishment and Growth after an Uneven-Aged Free Selection Regeneration Harvest in the Northern Rocky Mountains, USA
Authors: Jain Theresa B. , Graham Russell T. , Byrne John C. , Bright Benjamin C.
Published: June 2020

Research Highlights: Forest management is trending toward creating multi-aged forest structures and diverse vegetative compositions. The challenge is successfully designing and implementing treatments that create these diverse forests. Regeneration establishment is the most important step when applying a silvicultural system because it determines future treatments and optimizes management options. This study provided the minimum canopy openings that favor the establishment of shade-tolerant and shade-intolerant tree species to inform the implementation of uneven-aged management. Background and Objectives: A replicated study was implemented in 2007 in moist mixed-conifer forests to design, apply, and test two silvicultural concepts, canopy opening size and site preparation. Our objective in 2015 was to evaluate tree regeneration establishment and growth and understory vegetation in relation to these two silvicultural concepts. Materials and Methods: Canopy opening sizes as measured by lidar ranged from 15% to 100%; and through the application of prescribed fire, mastication, pile and burn, or no site preparation, different combinations of forest floor substrates were created. We stratified our study area into five canopy opening classes and four site preparation treatments. Using this stratified sampling scheme, we located 65 plots and measured tree species, abundance, 5-year height growth, and vegetative lifeforms. Results: The pile and burn site preparation favored the establishment of all six tree species. The canopy opening size of 55% to 92% favored the regeneration of both shade-tolerant and shade-intolerant species. Grand-fir 5-year height growth was significantly influenced by site preparation and canopy opening, and western white pine 5-year height growth was only influenced by canopy opening. Treatments did not influence vegetative richness. Conclusions: This study provided key treatment parameters in designing the regeneration step for uneven-aged management strategies with the goal of creating vegetative diversity and establishing shade-intolerant tree species in moist mixed-conifer forests.
Bird Assemblage Recovery in a Chronosequence of Tropical Dry Forests in Costa Rica
Authors: Hilje Branko , Sánchez Natalie V. , Bayne Erin M. , Sánchez-Azofeifa Arturo
Published: June 2020

Research Highlights: While forest structure recovery in successional tropical forests is well studied, the recovery of fauna and changes in species composition and assemblage along forests succession is not well understood in many areas of the Neotropics like tropical dry forests (TDFs). Background and Objectives: To compare bird species richness and assemblage in tropical dry forests (TDFs) of different ages of recovery from cattle ranching and relate both to forest structural characteristics. Materials and Methods: To sample bird species richness and assemblage in 16 successional forest of different ages (i.e., 20, 30, 40, and 60 years old) using autonomous sound recording units in the TDFs in Costa Rica. Results: A total of 64 species of birds was detected across all forest age classes. The highest species richness was found in the 20-year-old class. Species richness decreased as canopy openness increased, suggesting low forest structural complexity and low availability of perches, nesting sites and food sources. However, bird assemblages were similar among the different forest age classes, suggesting that age itself was not a strong predictor, likely because of high variation in structure within age classes. Conclusions: TDFs can recover structural characteristics important to birds in only a few decades, supporting a rapid bird species assemblage recovery. However, this seems to depend on the starting conditions of the site prior to being recovered. Young TDFs, 20 years old, provide similar habitats for birds as 60-year-old forests do. These findings provide relevant information on the influence of TDF recovery after severe human impact on a highly threatened ecosystem.
An Effect of Urban Forest on Urban Thermal Environment in Seoul, South Korea, Based on Landsat Imagery Analysis
Authors: Lee Peter Sang-Hoon , Park Jincheol
Published: June 2020

The urban heat island effect has posed negative impacts on urban areas with increased cooling energy demand followed by an altered thermal environment. While unusually high temperature in urban areas has been often attributed to complex urban settings, the function of urban forests has been considered as an effective heat mitigation strategy. To investigate the cooling effect of urban forests and their influence range, this study examined the spatiotemporal changes in land surface temperature (LST) of urban forests and surrounding areas by using Landsat imageries. LST, the size of the urban forest, its vegetation cover, and Normalized Difference Vegetation Index (NDVI) were investigated for 34 urban forests and their surrounding areas at a series of buffer areas in Seoul, South Korea. The mean LST of urban forests was lower than that of the overall city, and the threshold distance from urban forests for cooling effect was estimated to be roughly up to 300 m. The group of large-sized urban forests showed significantly lower mean LST than that of small-sized urban forests. The group of urban forests with higher NDVI showed lower mean LST than that of urban forests with lower mean NDVI in a consistent manner. A negative linear relationship was found between the LST and size of urban forest (r = −0.36 to −0.58), size of vegetation cover (r = −0.39 to −0.61), and NDVI (r = −0.42 to −0.93). Temporal changes in NDVI were examined separately on a specific site, Seoul Forest, that has experienced urban forest dynamics. LST of the site decreased as NDVI improved by a land-use change from a barren racetrack to a city park. It was considered that NDVI could be a reliable factor for estimating the cooling effect of urban forest compared to the size of the urban forest and/or vegetation cover.
Consumer Preferences and Acceptance of Meat Products
Authors: Garmyn Andrea
Published: June 2020

At the point of purchase, consumers often use extrinsic cues such as color, marbling, leanness, packaging, and price to determine which meat product(s) to buy [...]
Identification of the Ovine Keratin-Associated Protein 2-1 Gene and Its Sequence Variation in Four Chinese Sheep Breeds
Authors: Wang Jianqing , Zhou Huitong , Hickford Jon G. H. , Luo Yuzhu , Gong Hua , Hu Jiang , Liu Xiu , Li Shaobin , Song Yize , Ke Na , Qiao Lirong , Wang Jiqing
Published: June 2020

Keratin-associated proteins are important components of wool fibers. The gene encoding the high-sulfur keratin-associated protein 2-1 has been described in humans, but it has not been described in sheep. A basic local alignment search tool nucleotide search of the Ovine Genome Assembly version 4.0 using a human keratin-associated protein 2-1 gene sequence revealed a 399-base pair open reading frame, which was clustered among nine previously identified keratin-associated protein genes on chromosome 11. Polymerase chain reaction–single strand conformation polymorphism analysis revealed four different banding patterns, with these representing four different sequences (A–D) in Chinese sheep breeds. These sequences had the highest similarity to human keratin-associated protein 2-1 gene, suggesting that they represent variants of ovine keratin-associated protein 2-1 gene. Nine single nucleotide variations were detected in the gene, including one non-synonymous nucleotide substitution. Differences in variant frequencies between fine-wool sheep breeds and coarse-wool sheep breeds were detected. The gene was found to be expressed in various tissues, with the highest expression level in skin, and moderate expression levels in heart and lung tissue. These results reveal that the ovine keratin-associated protein 2-1 gene is variable and suggest the gene might affect variation in mean fiber diameter.
The Location of the Pseudoautosomal Boundary in Silene latifolia
Authors: Krasovec Marc , Zhang Yu , Filatov Dmitry A.
Published: June 2020

Y-chromosomes contain a non-recombining region (NRY), and in many organisms it was shown that the NRY expanded over time. How and why the NRY expands remains unclear. Young sex chromosomes, where NRY expansion occurred recently or is on-going, offer an opportunity to study the causes of this process. Here, we used the plant Silene latifolia, where sex chromosomes evolved ~11 million years ago, to study the location of the boundary between the NRY and the recombining pseudoautosomal region (PAR). The previous work devoted to the NRY/PAR boundary in S. latifolia was based on a handful of genes with locations approximately known from the genetic map. Here, we report the analysis of 86 pseudoautosomal and sex-linked genes adjacent to the S. latifolia NRY/PAR boundary to establish the location of the boundary more precisely. We take advantage of the dense genetic map and polymorphism data from wild populations to identify 20 partially sex-linked genes located in the “fuzzy boundary”, that rarely recombines in male meiosis. Genes proximal to this fuzzy boundary show no evidence of recombination in males, while the genes distal to this partially-sex-linked region are actively recombining in males. Our results provide a more accurate location for the PAR boundary in S. latifolia, which will help to elucidate the causes of PAR boundary shifts leading to NRY expansion over time.
Efficacy and Safety of Holmium Laser Lithotripsy Under Local Anesthesia in the Treatment of Urethral Stones in Elderly Male Patients
Authors: Atılgan Dogan , Kölükçü Engin , Fırat Fatih , Kölükçü Vildan
Published: June 2020

The elderly population has been increasing significantly in our century. In our study, it was aimed to analyze the treatment results of elderly male patients who underwent holmium laser lithotripsy (HLL) for urethral stones under local anesthesia. We evaluated a total of 31 male patients, aged ≥65 years, diagnosed with urethral stones and treated with HLL under local anesthesia. We noted the demographic data and visual pain scores (VAS) of the patients and the duration of the operation and hospital stay. Our analysis involved both the success rates of the surgical procedure and the complication rates according to the modified Clavien classification. In addition. we determined the patients’ preoperative clinical status using the Charlson comorbidity index (CCI). The mean age of the patients was 71.65 ± 8.19 years. Acute urinary retention was the most common complaint (45.2%). Their mean scores were 7.68 ± 2.53 according to CCI. The average operation time was 15.48 ± 5.22 min and the VAS was 2.03 ± 1.08. All patients were stone-free and there was a marked improvement in their symptoms None of them stayed in the hospital for more than one day. We did not observe any Grade 3 or higher complications. In light of the data obtained in our study, we concluded that HLL is an effective and reliable method to treat urethral stones under local anesthesia in elderly male patients.
The Impact of Emotional Symptoms and Family Support on the Association Between Homophobic Bullying and Sedative/Hypnotic Use among Gay and Bisexual Men in Taiwan: A Moderated Mediation Model
Authors: Li Dian-Jeng , Chang Yu-Ping , Chen Yi-Lung , Yen Cheng-Fang
Published: June 2020

Sedative/hypnotic use and homophobic bullying have become a big mental health concern for gay and bisexual men. However, few studies have investigated the mediators and moderators of the association between them. The current study aimed to build a conceptual model to estimate the mediating effect of emotional symptoms and the moderating effect of family support on this association among gay and bisexual men in Taiwan. A total of 500 gay or bisexual men were recruited for the study. Their history of homophobic bullying, their experience of sedative/hypnotic use, their perceived family support, and their current emotional symptoms were evaluated using self-reporting questionnaires. A moderated mediation model was developed to test the mediating effect of emotional symptoms and the moderating effect of family support. A higher level of homophobic bullying was significantly associated with sedative/hypnotic use among gay and bisexual men and this was mediated by a higher severity of emotional symptoms. A moderating effect of family support was identified, wherein the mediating effect of emotional symptoms was weaker when there was a higher level of perceived family support, thus revealing the protective effect of family support. The significant impact of emotional symptoms and family support on the association between homophobic bullying and sedative/hypnotic use was identified. Timely interventions for emotional symptoms and the enhancement of family support are crucial for gay and bisexual men.