bluuebunny/crossref_metadata_2025 huggingface dataset:
El espíritu de lo poético: hacia un diálogo entre Japón y la Amazonía
Authors: Melchy Ramos Yaxkin
Published: January 2025

¿Qué tipo de pensamiento sobre la naturaleza de la palabra conecta las animaciones japonesas del estudio Ghibli con los cantos medicinales amazónicos? Este artículo delinea el parentesco poético entre los pueblos de la Amazonía y del Japón para responder a la pregunta ¿Cómo se podría emparentar la poética del Este de Asia con la amerindia amazónica? Concretamente este artículo se centrará en ejemplos de la cultura japonesa y shipibo-konibo desde una perspectiva etnográfica y ecopoética. La tesis de este artículo es que hay tres puntos de similitud evidentes: la concepción del panlingüísmo (que todos los seres tienen la facultad de expresarse mediante el lenguaje); la concepción de una potencia realizativa de la palabra sobre la materia y el corazón de los seres; y la figura del poeta-sabio que incorpora estas dos concepciones en su expresión. Primero, se trazan algunos principios de la concepción japonesa del panlingüísmo poético (hangengoron) y del espíritu de la palabra (kotodama) y dos modelos que sitúan estos conceptos en diálogo con Occidente basándose en los trabajos de autores japoneses y según el marco interpretativo del animismo japonés. En segundo lugar, se realiza una exposición comparativa entre ejemplos japoneses y shipibos, acompañada de reflexiones a partir de la etnografía y la semiótica cósmica shipibo-konibo de Pedro Favaron y la teoría de la innovación indígena por medio de la creación vocal de Bernd Brabec. A partir de esta exposición se plantean similitudes entre el pensamiento del koshi joi (palabra fuerte) y el pensamiento del kotodama (espíritu de la palabra) y la concepción en ambas culturas de que los seres vivientes poseen un grado de conciencia y expresión que los habilita como sujetos que participan de un diálogo cósmico. Estas similitudes se evidencian entre las narraciones de los médicos tradicionales shipibo-konibo (onanyabo) sobre encuentros con los dueños espirituales (ibo) de plantas medicinales y obras dramáticas japonesas sobre encuentros entre hombres santos japoneses (hijiri) y los espíritus (kami) de plantas; entre los ritos agrícolas que suponen el entendimiento de que árboles frutales comprenden y responden a las palabras humanas, y entre la poética de la recitación rítmica de los cantos (bewa), cantos medicinales (rao bewabo) y la recitación rítmica de poemas-cantos (waka), invocaciones arcaicas (norito), bendiciones budista-sintoístas llamadas kajikito e invocaciones budistas llamadas nenbutsu; así como en un recato lingüístico y la conciencia del peligro de la brujería. Finalmente se presentan las conclusiones y una reflexión sobre los aportes ecológicos de un diálogo entre poéticas y etnolingüísticas del Sur y el Este global.
"Monilla Amena". Principios amazónicos para entender la producción cultural del mundo amerindio – Abiayalense
Authors: Rojas-Sotelo Miguel
Published: January 2025

Usando una de las historias de origen Amazónico, Monilla Amena (el árbol de la vida y abundancia), se puede insertar críticamente la producción cultural y artística de este territorio transnacional y dar cuenta de artistas-territorio amazónicos que con agencia actúan sobre espacios hegemónicos de producción cultural. Este texto ofrece unos principios para entender la producción cultural del mundo amazónico, usa este mito como línea de tiempo y espacio, y pone a la estética situada y la práctica encarnada como ejes metodológicos. Esta aproximación, en tres dimensiones, contextualiza y sitúa cada práctica a su lugar de enunciación y enfatiza cómo el sujeto productor cultural encarna, literalmente, su territorio como interrupción colectiva y no solo  individual. Adicionalmente introduce las nociones de fábula, diálogo, escucha en una suerte poliglotismo humananimal y vegehumano del mundo amazónico. Esta es una lectura crítica a las disciplinas académicas que miran a los productos culturales, categorizándolos y separándolos en ejercicios taxonómicos de captura y control. Para este ejercicio, los productores culturales son denominados artistas-territorio, pues trabajan situada y contextualmente y en continuo diálogo intercultural. Sus prácticas encarnadas son actos y eventos de tipo documental simbólico (político-estético) que interrumpen espacios dentro y fuera del mundo del arte y la cultura como estrategias para ejercer soberanía cultural desde el mundo amazónico. El corpus a tratar son pinturas rupestres ubicadas en los tepuyes precámbricos del Amazonas colombiano. Que se contrasta con el análisis de una pieza audiovisual contemporánea que representa al pueblo shipibo-konibo del noreste de Perú (Favarón, Bensho). Finalmente, el texto introduce a la generación emergente de artistas-territorio Pan Amazónicos. Entiéndase esta contribución también como un homenaje al maestro Fernando Urbina Rangel, guía al mundo amazónico y como una práctica cultural encarnada, ritualizada, situada y contextual que, de otra forma, sería un simple ejercicio académico.
Pintar un nuevo kené en territorios de migración y crisis medioambiental: Olinda Silvano "Reshinjabe" y el colectivo "Soi Noma"
Authors: Vidarte Basurco Giuliana
Published: January 2025

El presente artículo propone analizar las prácticas de creación, inspiradas en los diseños del kené, de la artista del pueblo shipibo-konibo Olinda Silvano Reshinjabe y del colectivo Soi Noma. A través de una revisión de las transformaciones que se han generado en el estudio y comprensión de los patrones tradicionales de esta nación amazónica —que han pasado de ser exhibidos como una expresión colectiva de arte popular a ser identificados como un medio de expresión de creadores indígenas contemporáneos— se contextualiza y analiza cómo estas artistas han sido partícipes de este proceso. Asimismo, se concluye que hoy en día ellas llevan los diseños del kené a la superficie de murales y a los lienzos, dentro de la institucionalidad y los medios de la creación contemporánea peruana, con la intención de difundir el valor de su identidad shipibo-konibo y de ser generadoras de ingresos económicos para sus familias y su comunidad. Además, afirman una crítica a las problemáticas medioambientales propias de la región amazónica y de la crisis climática global, así como visibilizan las situaciones de precariedad y violencia sufridas por las colectividades migrantes de la Amazonía en la ciudad de Lima y contribuyen en ampliar los límites de lo que es definido y comprendido como arte contemporáneo en el Perú.
Palabras que honran y sanan. Poética en el canto visionario de Inin Niwe, Amazonía Perú
Authors: Parga-León Angela Laura
Published: January 2025

Bajo la investigación amplia acerca de la obra visual y literaria vegetalista de una familia medicinal shipibo konibo en Santa Clara de Yarinacocha, Ucayali, Amazonía, Perú, se ha madurado desde la antropología del arte y en convergencia metodológica con la filosofía de la imaginación, el acercamiento etnográfico y estético al texto literario Ikaro (2018) del poeta Pedro Favaron Peyón. Este último, es también un visionario Onanya, quien ha recibido los conocimientos medicinales ancestrales de su familia política, cultivados desde antiguo. Atendiendo a las figuras imaginales y ascensionales que el registro escrito evoca y traslada desde el canto curativo, se establece el régimen diurno del poema cimentado por dicho visionario en su rol de sabio curativo y vidente. Su nombre shipibo, Inin Niwe, testifica la experiencia trascendente de su imaginación creadora, imaginación alada y perfumada.
Quispe-Agnoli, R. y Brian, A. (ed.) (2022). "Latin American Literature in Transition Pre 1492-1800". Cambridge: Cambridge University Press.
Authors: Soro Cuesta Esther
Published: January 2025

Reseña del libro Quispe-Agnoli, R. y Brian, A. (ed.) (2022). Latin American Literature in Transition Pre 1492-1800. Cambridge: Cambridge University Press, 385 pp, ISBN: 9781108976893.
Gobeo de Vitoria, P. (2023). "Naufragio y peregrinación". Edición y actualización del texto a cargo de Miguel Zugasti. Prólogo de Luis Gorrochategui. Barcelona: Editorial Crítica.
Authors: Aracil Varón Beatriz
Published: January 2025

Reseña del libro Gobeo de Vitoria, P. Naufragio y peregrinación. Edición y actualización del texto a cargo de Miguel Zugasti. Prólogo de Luis Gorrochategui. Barcelona: Editorial Crítica, 2023, 264 pp, ISBN 978-84-9199-527-2.
SOME PROPERTIES OF ALMOST JOINTLY PRIME (R,S)-SUBMODULES
Authors: Yuwaningsih Dian Ariesta , Nurnugroho Burhanudin Arif , Sholiha Diniar Mar’atus , Lolita Lolita
Published: January 2025

Let 𝑅 and 𝑆 be rings with identity. The definition of prime submodule has been generalized to the almost prime submodule. In addition, the definition of prime submodule has also been carried over to the (𝑅,𝑆)-module structure, which is called jointly prime (𝑅,𝑆)-submodules. However, as a generalization of prime submodules, the concept of almost prime submodules has not been carried over to (𝑅,𝑆)-module structures. In this paper, we construct the definition of almost jointly prime (𝑅,𝑆)-submodules as the generalization of jointly prime (𝑅,𝑆)-submodules. We also present several necessary and sufficient conditions for an (𝑅,𝑆)-submodule to be an almost jointly prime (𝑅,𝑆)-submodule.
Recognizing the Spatial Distribution and Voronoi Patterns of the Recorded Earthquake Epicenters in Sunda Strait, Indonesia
Authors: Muliawati Triyana , Lestari Fuji , Alvionita Mika , Satria Ardika , Harbowo DG
Published: January 2025

Currently, Sunda Strait is one of the most active transportation hubs. However, this region also bears a notable history of geohazards associated with the dynamics of tectonic activity of the Eurasian and Indo-Australian tectonic plates, such as the super-eruption of Krakatoa volcano in 1883, the Sunda Strait tsunami in 2018, and decades of frequent earthquakes. To address these challenges, this study conducted a statistical analysis of the frequency and distribution of seismic activities in the Sunda Strait region based on recorded epicenter data in the United States Geological Survey's (USGS) Earthquake catalog. We assembled 440 multivariate earthquake data points between 1990 and 2023 (over three decades). The results of this study indicate that the machine learning approach precisely identifies four relevant parameters for -means clustering, followed by an analysis of silhouette values to recognize Voronoi patterns. These statistical patterns also have significant implications for the number of epicenter clusters and recognizing their spatial distribution. It provides a new understanding of the spatial-temporal characteristics and locates the list of frequent earthquake regions. Having all the necessary information would help to comprehensively evaluate geohazard risks in Sunda Strait region.
E-FLOATING EXECUTION: INOVASI EKSEKUSI ELEKTRONIK PENGADILAN TATA USAHA NEGARA DALAM PEMBANGUNAN HUKUM PROGRESIF
Authors: Lumbanraja Brata Yoga
Published: January 2025

Technological developments influence the State Administrative Court system. Forming the E-Court from a progressive legal perspective is an effort by the law itself to adapt to the times. The aim of writing this article is to provide innovative electronic systems for administrative courts in Indonesia. The concept of E-Floating Execution (Electronic Floating Execution) will be developed with the help of progressive legal theory thinking.  doctrinal research method with a conceptual and comparative approach. This concept refers to using digital technology to automate and speed up the process of executing court decisions. The French state has the application "Télérecours" serving as an important tool to facilitate electronic communication at every stage of procedures before administrative courts. The Concept of E-Floating Execution (Electronic Floating Execution) Innovation in Electronic Execution of State Administrative Courts in Progressive Legal Development has the potential to Increase Accessibility, Speed Up Legal Processes, and Transparency and Accountability.
KEDUDUKAN PEMERINTAH DALAM SISTEM PENGEMBANGAN E-COMMERCE DARI SEGI KEPERDATAAN BERDASARKAN ASAS KEPASTIAN HUKUM
Authors: Marbun Bachtiar , Santoso Budi , Yunanto Yunanto
Published: January 2025

This research aims to analyze the position of the government in the e-commerce development system by providing legal certainty in e-commerce development and creating a civil perspective to develop the system from a civil perspective based on the principle of legal certainty. The method used is normative juridical using three types of legal materials: primary, secondary and tertiary materials. Data collection by analyzing materials used in the library, using descriptive qualitative methods. The results show that from a civil aspect, the government's role in the development of the e-commerce system is based on the principle of legal certainty regulated in the 7th edition with the 2014 Trade Code. The E-Commerce Regulation provides a clear understanding of the Electronic Transaction System (ETS).
Pembentukan Lembaga Peradilan Khusus Pemilihan Umum dalam Rangka Mewujudkan Electoral Justice System
Authors: Zulkarnain Muhammad Haris
Published: January 2025

Objective: The aim of this research is to identify the urgency of establishing a special election justice institution in order to realize an election justice system in Indonesia.Methodology/Approach/Design: This research uses a normative juridical method with a qualitative approach. This method allows researchers to analyze statutory regulations, the role and authority of institutions that handle electoral disputes and disputes in Indonesia so far, as well as case studies of the form of special election judicial institutions in other countries.Results and Discussion: In facing every problem related to holding elections in Indonesia, effective efforts and systems are needed to overcome them. Realizing an electoral justice system in elections, one of which is through the establishment of a special election justice institution. Special election institutions are tasked with completing resolutions and election cases more quickly, effectively and focused because they are carried out by just one institution. The format and form of special election judicial institutions can be adapted to the interests and electoral problems that exist in Indonesia.Practical Implications: This research has practical implications for realizing an electoral justice system in the implementation of democratic parties in Indonesia. The existence of a special election judicial institution can help change the current state's legal and institutional practices to be better, integrated and not overlapping between institutions in their authority to handle electoral disputes and disputes, whether in presidential elections, legislative elections, or regional head elections. It is hoped that efforts to establish a special election judicial institution can provide justice, benefit and legal certainty regarding disputes and disputes in elections in Indonesia.Novelty/Value: This research contributes to providing new ideas in handling election cases and disputes in Indonesia through a special election judicial institution. The value of this research lies in a better understanding of the importance of the electoral justice system so that the quality of the implementation of democracy in Indonesia can continue to be improved. Efforts to create an effective legal system based on the legal system theory of Lawrence Mier Friedman and the goals to be achieved from this system based on Satjipto Rahardjo's legal political theory are the added value of this research.Keywords: General Elections. Special Judicial Institutions. Electoral Justice System.
Život a dílo Josepha Flavia
Authors: Mason Steve
Published: January 2025

The works of Josephus (37 – ca. 100 CE) have been extensively cited ever since he wrote them. Strangely enough, however, hardly any of his many users, prior to the 1980s, asked basic questions about the structures, themes, and audiences of these compositions – about what he meant to convey, using his typical language, rhetoric, and contexts guides. Yet how can we use his material if we do not know what he meant by it? This essay provides a brief orientation to Josephus’ life and to reading his works as intelligent compositions. It is not meant to be definitive on any point, but it provides enough documentation that readers may further investigate these questions without limit, for their own purposes.
John Barton: Historie Bible
Authors: Hejzlar Pavel
Published: January 2025

Book review on John Barton: Historie Bible, Praha: Kalich, 2022, ISBN 978-80-7017-315-2
The Impact of the Transatlantic Educators Dialogue on the Contemporary Educational Process in Schools Collaborating in the United States and Europe
Authors: Olędzka Monika , Oldham Rhett
Published: January 2025

This article explores the impact of the Transatlantic Educators Dialogue (TED) Program on modern educational practices in schools across the US and Europe, analyzing survey results from participants. It highlights how global education shapes attitudes among students and educators. The TED Program aims to cultivate responsible, culturally aware global citizens through interdisciplinary learning that integrates diverse fields of knowledge. It promotes cultural, linguistic, and social competencies through international collaboration. Surveyed teachers and students report significant social and linguistic development, appreciating the chance to compare educational systems globally. Both data and testimonials underscore TED’s profound influence on international education, fostering personal growth and enhancing global citizenship.
Integration of neuromuscular control for multidirectional horizontal planar reaching movements in a portable upper limb exoskeleton for enhanced stroke rehabilitation
Authors: Zhao Yongkun , Mao Juzheng , Zhang Mingquan , Wu Haijun , Jiang Jiatong , Jing Shibo
Published: January 2025

Globally, the prevalence of stroke is significant and increasing annually. This growth has led to a demand for rehabilitation services that far exceeds the supply, leaving many stroke survivors without adequate rehabilitative care. In response to this challenge, this study introduces a portable exoskeleton system that integrates neural control mechanisms governing human arm movements. This design leverages neuroplasticity principles to simulate natural movements, aiming to reactivate and strengthen neuromuscular connections and thus enhance rehabilitation outcomes. A tailored musculoskeletal model of the human arm and an associated cost function were developed to accurately replicate the planar motion trajectories of a healthy human arm across 32 directions. The application of a Proportional-Derivative (PD) controller enables precise tracking of these trajectories by the exoskeleton. Individual testing has demonstrated high consistency between the exoskeleton-driven motion paths and the simulated trajectories, especially in trajectory accuracy along the X and Y axes. These findings support the efficacy of integrating advanced neural control strategies with practical exoskeleton designs in stroke rehabilitation.
Implementing a radial basis function model to anticipate the outcomes of the gasification
Authors: Cui Hongfang , Su Ning , Cui Hongyan
Published: January 2025

Hydrogen (H₂) and nitrogen (N₂) are both critical components in gasification processes, making efficient conversion of carbonaceous feedstocks into valuable gases with reduced environmental impact indispensable. This study demonstrates a state-of-the-art approach to predictive modeling for these quantities at high accuracy while allowing cost-effective solutions under a variety of operational conditions, enhancing safety, and enabling data-driven optimization. This work develops a new framework that incorporates the radial basis function model with two state-of-the-art optimization algorithms, namely the Zebra Optimization Algorithm (ZOA) and Flow Direction Algorithm (FDA), to enhance the predictive accuracy of gasification processes. This is a new frontier in optimizing the sustainable conversion of carbonaceous feedstocks, demonstrating the potential of data-driven methodologies in process efficiency and environmental sustainability. The RBFD model resulted in outstanding anticipation capability for H2, reaching an exceptional R
2 value of 0.997 during the whole period of testing. On the other hand, the RBZO framework proved to be the strongest predictor for N2 anticipation, presenting an outstanding R
2 of 0.994 during the testing and validation phases. The RBFD and RBZO frameworks showed significantly higher productivity compared to the conventional RBF model, as evidenced by accuracy metrics like MSE, RMSE, and WAPE.
Medical education embraces new transformative opportunities
Authors: Wang Weimin
Published: January 2025

With the development of technologies such as artificial intelligence (AI), big data, and virtual reality, medical education is facing significant reform opportunities. The fourth-generation medical education reform emphasizes interdisciplinary cooperation, focuses on health rather than just disease treatment, and uses AI technology to enhance the quality of education. The reform requires cooperation from multiple parties, including government top-level design, optimization of medical school organizational structures, and the cultivation of medical students’ sense of responsibility and mission. The goal is to build a fair and efficient health service system.
MitoStores: stress-induced aggregation of mitochondrial proteins
Authors: Kaushik Pragya , Herrmann Johannes M. , Hansen Katja G.
Published: January 2025

Most mitochondrial proteins are synthesized in the cytosol and post-translationally imported into mitochondria. If the rate of protein synthesis exceeds the capacity of the mitochondrial import machinery, precursor proteins can transiently accumulate in the cytosol. The cytosolic accumulation of mitochondrial precursors jeopardizes cellular protein homeostasis (proteostasis) and can be the cause of diseases. In order to prevent these toxic effects, most non-imported precursors are rapidly degraded by the ubiquitin-proteasome system. However, cells employ a second layer of defense which is the facilitated sequestration of mitochondrial precursor proteins in transient protein aggregates. The formation of such structures is triggered by nucleation factors such as small heat shock proteins. Disaggregases and chaperones can liberate precursors from cytosolic aggregates to pass them on to the mitochondrial import machinery or, under persistent stress conditions, to the proteasome for degradation. Owing to their role as transient buffering systems, these aggregates were referred to as MitoStores. This review articles provides a general overview about the MitoStore concept and the early stages in mitochondrial protein biogenesis in yeast and, in cases where aspects differ, in mammalian cells.
A Conjectural Variations Approach to Detecting Collusion: The Broiler Chicken Antitrust Litigation Case
Authors: Sheng Qiwen , Vukina Tomislav
Published: January 2025

In this paper we investigated the dynamic of competition in the U.S. broiler chicken industry from 2000 to 2023, focusing on the detection and the implications of alleged collusive behaviour. By employing a structural econometrics approach, we estimated the conjectural elasticities, offering an explanation for how potential collusive arrangements evolved over time. Our most important results show that the alleged collusion period elevated the conjectural elasticities for all defendants but increased the conjectural elasticity of the group of three largest publicly traded broiler companies the most. These results suggest that the industry tacit collusion could have morphed into explicit collusion, with the largest three firms being the likely leaders of the conspiracy. In addition, the computed Lerner indexes show that the market power has increased during the collusion period relative to the pre-collusion period and remained elevated afterwards, suggesting stubborn impact of collusion on competition even during the post collusion period.
Clinical and genetic diagnosis of first cohort of differences of sexual development in the Iranian population
Authors: Rastari Mandana , Askari Masomeh , McElreavey Kenneth , Bashamboo Anu , Rokhsattalab Zeinab , Razzaghy-Azar Maryam , Bakhshi Mahdieh , Totonchi Mehdi
Published: January 2025

Differences of sex development (DSD) refer to various congenital conditions affecting the urogenital and hormonal systems. Accurate diagnosis and personalized management are crucial for supporting patients through complex decisions, such as those related to gender identity. This study represents the first comprehensive investigation into DSD in Iran, analyzing patient’s clinical and genetic data between 1991 and 2020. Karyotype analysis was performed on 69 patients without a molecular diagnosis, with sex chromosome DSD excluded. Presence of SRY gene evaluated in all sex reversal patients. Whole exome sequencing (WES) was used for 26 undiagnosed patients, revealing pathogenic variants in WT1, NR5A1, DHX37, AR, CYP17A1, and LHCGR genes. The most common diagnosis was testicular TDSD, identified in 42 patients (60.86 %), with the SRY gene being the primary cause in 36 of these patients. The study highlights the importance of genetic analysis in identifying novel and rare gene variants, particularly within the steroid hormone and gonad differentiation pathways, for both 46, XY and 46, XX DSD. These findings emphasize the need for genetic analysis in providing personalized patient care and tailored counseling to help individuals navigate complex decisions, including those involving gender identity.
Elastographic evaluation for fatty liver disease in north Indian children and adolescents with type 1 diabetes
Authors: Gupta Vinod , Dayal Devi , Bhatia Anmol , Sachdeva Naresh , Lal Sadhna , Bala Anju , Attri Savita Verma
Published: January 2025

Objectives

The prevalence and predisposing factors to metabolic dysfunction-associated fatty liver disease (MAFLD) in children with type 1 Diabetes (T1D) living in developing countries are unknown.

Methods

A cross-sectional study was conducted in children with T1D. The presence of liver fat and tissue stiffness were assessed by ultrasonography and shear-wave elastography (SWE), respectively. The SWE values were correlated to body mass index (BMI), glycemic control, disease duration, and gamma-glutamyl transferase (GGT). Healthy non-obese children (n=36) were recruited as controls.

Results

One hundred children with T1D were grouped (Group A-C) according to the disease duration (<5, 5–10, and >10 years, respectively). The mean diabetes duration and glycated hemoglobin were 5.9 ± 4.0 years and 8.2 ± 0.55 %, respectively. The mean SWE values were significantly higher in the patient groups compared to controls (5.07 ± 0.67, 5.27 ± 0.65, 5.16 ± 0.50, vs. 4.80 ± 0.82 kPa, p-value 0.006). The liver stiffness based on SWE showed a positive but weak relationship with BMI, diabetes duration, glycemic control, and GGT levels. A significantly higher number of children with T1D had MAFLD [9(20 %), 7(24.1 %), 7(26.9 %), vs. 1(3 %), p-value <0.001] based on ultrasonography.

Conclusions

Children with T1D showed higher liver stiffness values than controls. A weakly positive relationship of liver stiffness was observed with BMI, duration of diabetes, glycemic control, and serum GGT. Approximately one-fourth of children with diabetes showed sonographic evidence of hepatic steatosis. Larger studies are needed to ascertain the effects of obesity, diabetes duration, and metabolic control on the prevalence and progression of MAFLD in children with T1D.
Recent advances on brain drug delivery via nanoparticles: alternative future materials for neuroscience applications; a review
Authors: Razavi Razieh , Khajouei Ghazal , Divsalar Fatemeh , Dawi Elmuez , Amiri Mahnaz
Published: January 2025

Essentially, the blood–brain barrier (BBB) serves as a line of demarcation between neural tissues and the bloodstream. A unique and protective characteristic of the blood–brain barrier is its ability to maintain cerebral homeostasis by regulating the flux of molecules and ions. The inability to uphold proper functioning in any of these constituents leads to the disruption of this specialized multicellular arrangement, consequently fostering neuroinflammation and neurodegeneration. Recent advancements in nanomedicine have been regarded as a promising avenue for improving the delivery of drugs to the central nervous system in the modern era. A major benefit of this innovation is that it allows drugs to accumulate selectively within the cerebral area by circumventing the blood–brain barrier. Although brain-targeted nanomedicines have demonstrated impressive achievements, certain limitations in targeting specificity still exist. In this examination, we scrutinize the distinctive physical and chemical attributes of nanoparticles (NPs) contributing to their facilitation in BBB traversal. We explore the various mechanisms governing NP passage over the BBB, encompassing paracellular conveyance, mediated transport, as well as adsorptive- and receptor-mediated transcytosis. The therapeutic success of NPs for the treatment of brain tumors has been extensively investigated through the use of various categories of NPs. Among these are polymeric nanoparticles, liposomes, solid lipid nanoparticles, dendrimers, metallic nanoparticles, quantum dots, and nanogels. The potential utility of nanoparticles goes beyond their ability to transport pharmaceuticals. They can serve as adept imaging contrast agents, capable of being linked with imaging probes. This will facilitate tumor visualization, delineate lesion boundaries and margins, and monitor drug delivery and treatment response. Versatile nanoparticles can be engineered to effectively target neoplastic lesions, serving dual roles in diagnostic imaging and therapeutic interventions. Subsequently, this discourse explores the constraints associated with nanoparticles in the context of treating brain tumors.
The interplay between gut microbiota composition and dementia
Authors: Ghannadzadeh Kermani pour Rad , Kamali Zounouzi Sara , Farshbafnadi Melina , Rezaei Nima
Published: January 2025

Recently, researchers have been interested in the potential connection between gut microbiota composition and various neuropsychological disorders. Dementia significantly affects the socioeconomics of families. Gut microbiota is considered as a probable factor in its pathogenesis. Multiple bacterial metabolites such as short-chain fatty acids, lipopolysaccharides, and various neurotransmitters that are responsible for the incidence and progression of dementia can be produced by gut microbiota. Various bacterial species such as Bifidobacterium breve, Akkermansia muciniphila, Streptococcus thermophilus, Escherichia coli, Blautia hydrogenotrophica, etc. are implicated in the pathogenesis of dementia. Gut microbiota can be a great target for imitating or inhibiting their metabolites as an adjunctive therapy based on their role in its pathogenesis. Therefore, some diets can prevent or decelerate dementia by altering the gut microbiota composition. Moreover, probiotics can modulate gut microbiota composition by increasing beneficial bacteria and reducing detrimental species. These therapeutic modalities are considered novel methods that are probably safe and effective. They can enhance the efficacy of traditional medications and improve cognitive function.
Recepción gramatical y actitudes ante la lengua a través de fuentes marginales de la América colonial hispana y de los primeros años de independencia
Authors: Rivas Zancarrón Manuel
Published: January 2025

The main objective of this work is to contribute to the study of grammatical reception and linguistic attitudes by examining some marginal sources of the Spanish language in Colonial America and during the first years of independence. The temporal delimitation that underlies this geographical space is another variable for determining the traces that grammatical thought has left in its historical development, since it seems that its transmission was justified or modified by certain socio-cultural and political conditions that have little to do with the successes or failures manifested in a specific grammatical theory. In other words, an approach to the allusions to grammatical treatises manifested in the different spaces of public opinion of a specific time and place, as well as to the set of linguistic attitudes that determine the concern for the methods leading to the teaching of languages, both dead and living, as well as languages in contact, would entail the study of a set of socio-cultural and ideological variables that will undoubtedly help to clarify why and how the transmission and reception of grammatical theories and linguistic attitudes was channeled in the period and geographical space under study.
El centro y la periferia: ideas y actitudes lingüísticas en torno al andalucismo lingüístico en la prensa decimonónica
Authors: Bastardín Candón Teresa
Published: January 2025

This article examines the spread of mainly lexical andalusianisms in the 19th century and their perception in the press. On the basis of various journalistic texts, the ideas and linguistic attitudes towards these provincialisms and their place in the general language will be analysed with the usual reference to academic work and its criteria. The conclusions underline the importance of these textual sources for the study of the history of linguistic dialectalisms in relation to the creation of a national linguistic standard and show the emergence of a centralist ideology and its multiple contradictions.
Zur Wortgeschichte von dt. Kartaune ‘Feldgeschützʼ
Authors: Schweickard Wolfgang
Published: January 2025

Germ. Kartaune ‘a siege gunʼ is based neither on Italian cortana nor on Italian or Medieval Latin quartana, as has been unanimously assumed up to now in German historical lexicography. In actual fact, it is a borrowing from the synonymous French courtal, pl. courtaux. The earliest German evidence appears – in the context of the Burgundian Wars – in the form kortauwen and cortauw in 1475 and in the form curtal and curtan in 1476. The variant with the final -n, which is limited to southern Germany, constitutes the basis for the later German standard form Kartaune. In the late 15th century, the term also passed from French into Italian, where the types cortaldi < French courteaux and cortale < French courtel can be distinguished.
Las estrategias de enseñanza del profesor como eje de investigación en Didáctica de Nivel Superior
Authors: Del Regno Dr.ª Patricia Mariel
Published: January 2025

Este artículo presenta algunas consideraciones en torno a la cuestión de las estrategias de enseñanza del profesor en el aula de nivel superior, basándose en algunas conceptualizaciones teóricas provenientes de la Didáctica de Nivel Superior y en algunos análisis y reflexiones en torno a determinados casos áulicos de investigación que la autora ha desarrollado en torno a dicho eje temático en los últimos años. En tal sentido, se consideran y resumen tres investigaciones realizadas por la autora –desde un enfoque cualitativo de estudio de casos – en aulas de instituciones públicas de educación superior, de diversas carreras, de la ciudad de Buenos Aires y del conurbano bonaerense. Una de dichas investigaciones ha sido realizada para la Tesis Doctoral, dirigida por el Dr. Miguel Fernández Pérez, presentada en Noviembre de 2011 en la Facultad de Educación de la Universidad Complutense de Madrid (UCM) y las otras dos investigaciones, dirigidas por la Dra. Elisa Lucarelli, se realizaron respectivamente durante el bienio 2012-2013 y posteriormente en el bienio 2014-2015 para la programación científica de la Universidad Nacional de Tres de Febrero (UNTREF). Se expondrán en este artículo algunas consideraciones sintéticas, tanto de marco teórico como de resultados empíricos de dichas investigaciones, con la intención de plantear –a partir de allí – algunas reflexiones sobre la enseñanza en el nivel superior y sobre la construcción disciplinar del campo de la Didáctica de Nivel Superior.
The Formation of Modern HighTech Industrial Production Within the "Industry 4.0" Concept Implementation
Authors:   Dnipro University n. Alfred Nobel, Dubnitskyi Volodymyr , Zakharchenko Vitaly ,   Odesa Polytechnic National University
Published: January 2025

The key technologies analysis of modern high-tech production
digitalization within the "Industry 4.0" concept implementation is proposed,
related to its organization, hardware and software automation, creation of
new mechanisms of inter-machine interaction, taking into account the place
and functions of such technologies in the structure of the general scientific
and technological development of high-tech enterprises. The concept, essence
and application potential of following basic tools are considered - digital
transformation as a cyber-physical system, Industrial IoT, product life cycle
management system, collaborative work, technological analysis of big data,
artificial intelligence and adaptive 3D printing technologies. The deep
interconnection and mutual influence of such technologies in high-tech
production reflects the systemic nature of the industrial structures
transformation and complex application in accordance with the level of
automation and robotics.
Modern aspects of innovative marketing. Problems and prospects of using innovative marketing by business in Ukraine
Authors:   Dnipro National University named after Oles Honchar, Smyrnova Tetiana
Published: January 2025

The article discusses modern aspects of innovative marketing.
The existing definitions of the term "innovative marketing" are
analyzed, the author's definition is proposed, the essence and main
goals are indicated. General aspects of innovative marketing are
analyzed: application of new technologies, orientation to changes in
consumer behavior, integration of digital platforms for product
promotion, adaptation to changes in the competitive environment. A
comparison of innovative marketing with traditional marketing is
made, the advantages and disadvantages of innovative marketing are
highlighted. The tools of innovative marketing, possible strategies,
as well as the stages of developing an innovative marketing strategy
are indicated. The problems of the implementation of innovative
marketing at the enterprises of Ukraine are highlighted, and the
prospects are encouraging, taking into account the global trends of
digitization and the growing interest in new technologies in business.
Investment Priorities for Agribusinesses in Ukraine's Recovery Process
Authors:   Odesa Polytechnic National University, Tetiu Andrii
Published: January 2025

The paper identifies the main investment priorities for agroindustrial enterprises in Ukraine that will contribute to the effective
recovery of the sector under wartime conditions. Strategies and
approaches to investing in the agro-industrial complex are analyzed,
particularly in the context of adaptation to European standards and
environmental requirements. The main problems and constraints for
the agricultural sector of Ukraine in wartime conditions are
identified. The role of international financial institutions and donors
in supporting agro-industrial enterprises is assessed, and
recommendations for improving cooperation and utilizing
international assistance are developed. The impact of environmental
and climatic factors on the recovery of the agro-industrial sector is
examined, and recommendations for implementing sustainable
practices are formulated. Recommendations are developed to
improve access to financing for small and medium-sized agricultural
enterprises to ensure their sustainable development. Strategies are
formulated to enhance the competitiveness of Ukrainian agroindustrial enterprises in the international market through the
implementation of innovations, improvement of production
processes, and adaptation to European standards.
Theoretical Foundations of the Organizational and Economic Mechanism of Enterprise Management
Authors:   Odesa Polytechnic National University, Kalinin Denys
Published: January 2025

The research is dedicated to the theoretical foundations of
the organizational and economic mechanism of enterprise
management, analyzing key factors that determine the
effectiveness of management in modern conditions. The main
elements of the organizational and economic mechanism, its
structure, functions, and the influence of external and internal
factors on the functioning of the enterprise are highlighted. The
role of adaptability of the mechanism in a changing environment
and the necessity for continuous monitoring and adjustment of
management strategies are emphasized. Practical
recommendations for improving the organizational and
economic mechanism are proposed, including the
implementation of integrated management systems that ensure
the efficient use of resources and processes, as well as support
for the innovative development of the enterprise. The importance
of risk management as a tool for minimizing the negative impact
of external and internal factors is also emphasized.
Flexibility of the Labor Market as a Tool for Effective and Development of Human Capital
Authors:   SO "Institute of Economics and Forecasting of the NAS of Ukraine", Blyzniuk Viktoriia , Yatsenko Lyubov ,   National Institute for Strategic Studies
Published: January 2025

The article is devoted to consideration of the issues of flexibility
and adaptability of the national labor market. It is noted that the
modern globalized labor market, which is actively developing in the
conditions of digital technologies, requires the adoption of effective
management decisions at all administrative levels in order to ensure
productive employment and provide signs of flexibility. The use of
the subject approach made it possible to consider various
manifestations of the flexibility of the labor market and to determine
the management mechanisms of its regulation. Modern
manifestations of the flexibility of the national labor force in the
conditions of a long war are given. The analysis of threats and
possibilities of flexibility of the labor market to ensure the conditions
for the realization and development of human capital made it
possible to propose effective management mechanisms in the
conditions of a protracted war.
Activity of Small Enterprises During the Period of Full-Scale Invasion in the Context of Restoration of Territorial Communities
Authors:   Odesа Polytechnic National University, Rudyk Oleh
Published: January 2025

The article examines the impact of Russia's full-scale
military invasion on small businesses, with a focus on small
private enterprises in Ukraine, which have suffered significant
losses and forced relocation. Despite the difficulties, small
businesses demonstrated the ability to adapt flexibly, which
contributed to their survival and even an increase in the number
of new registrations. The author finds that in 2022, after the
resumption of registration processes, more than 200 thousand
new small businesses were opened, and in 2023 the number of
registrations exceeded 300 thousand. The article emphasizes the
importance of studying the state of small business, and in
particular small private enterprises, during the war to predict its
role in the post-war recovery of Ukraine's territorial
communities.
Ethics in doctorate research: A journey through research paradigms
Authors: Mat Razali Nur Nadiah Salihah , Fernando Yudi
Published: January 2025

This study aims to explore the ethical research elements that doctorate students need to comply with in their research journey. This study will elucidate five philosophical paradigms in management research which are, positivism, critical realism, post modernism, interpretivism, and pragmatism. Examining critical aspects of positivism, critical realism, postmodernism, interpretivism, and pragmatism involved reviewing information from publications as part of the contextual analysis process. The research findings show there are five paradigm shifts in Business management studies and each of the paradigm have their uniqueness which assist the doctoral study to adopt and adapt the ethical research value their research process.  The implication of this study will enhance the mastery of knowledge about the research paradigms. Hence, the doctorate students may have proper guideline in bring out their research ideas until research discussion with a well direction. Research paradigms known as the best research procedures to use when doing research in each of the paradigms under discussion were identified, along with suggested solutions to obstacles in this regard. It was recommended that prospective researchers be provided with suitable direction on selecting research paradigms for doctoral studies that comply with ethical standards. The research paradigm as one of the ways to comprehend the clear whole research direction including research design, research methodology, statistical analysis and etc.
Identification of supplier partnership critical success factors in the construction industry
Authors: Mahmud Fatimah , Syed Abu Bakar Sharifah Nora Fadiani
Published: January 2025

In the construction industry, supplier partnerships and collaboration are crucial for overcoming competing objectives and fostering growth. Challenges such as interpersonal conflicts, lack of trust, unequal risk sharing, overdependence, cultural barriers, inefficient problem-solving, communication breakdowns, insufficient effort to sustain long-term cooperation, inadequate training, and exclusion can disrupt these partnership and hinder project progress. Thus, this paper aims to investigate the critical success factor (CSF) of supplier partnerships in the construction industry. The survey-based study was conducted using purposive sampling among top management in construction companies, resulting a final sample of 190 respondents. The study highlights the importance of trust, mutual commitment, and effective dispute resolution in shaping key relationship traits linked to successful supplier partnerships in the construction industry. The findings on CSFs in supplier partnerships provide valuable insights for construction practitioners, helping them prevent disputes, improve partnership efficiency, and eliminate adversarial interactions.
Ignoring the Urgent Needs of the Real Estate Market by Chinese Banks
Authors:   Ivan Franko National University of Lviv, Hurnyak Ihor , Proniewski Marek ,   University of Bialystok, Niedźwiecki Arkadiusz ,   University of Bialystok
Published: January 2025

Purpose – The main purpose of this article is to demonstrate the growing gap between China’s banking sector and the real estate market, and the emergence of rationality in their interaction. A related goal is to reveal the primacy of institutional reforms as a tool for solving problems of insufficient business financing. Research method – For the analysis of the dynamics of the real estate and banking services markets, the toolkit of the optimal portfolio is used. Manipulation of financial indicators is an attempt to vary the influence of the ratio of profitability and risk. To demonstrate the comparability of the results based on other methods, the ARIMA method was used. All the mentioned tools are implemented on the basis of Python packages. Results – At the moment, the problem of insufficient capital in the Chinese RE development market cannot be restored by the national stock market and an increasingly autonomous banking sector. At the same time, European stock markets still have a negative perception of Chinese business, which is reflected in the results of the investment portfolios. As the rules of the game (institutional environment) remain unchanged, there are no special prospects for the Chinese real estate development sector.