bluuebunny/crossref_metadata_2025 huggingface dataset:
Preliminary Wound Healing Activity of Polyherbal Formulation Containing Cinnamon zeylanicum, Centella asiatica and Moringa oleifera
Authors: UBHRANİ Gautami , TALATİ Het , BHATT Punitkumar , SORATHİA Kishorkumar , SUHAGİA Bhanubhai
Published: August 2023

In the present work, a polyherbal gel formulation for wound healing activity was developed using 70% methanolic extract of Centella asiatica leaves, methanolic extract of Cinnamomum zeylanicum Nees stem bark as well as oil of Moringa olifera seed. The developed formulation was evaluated for organoleptic parameters like colour, odour, texture and physicochemical parameters like a loss on drying (LOD), pH, viscosity, spreadability, skin irritation study, etc. In-vitro antibacterial activity of both the extracts and oil of M. oleifera was carried out against two pathogenic bacteria Escherichia coli and Staphylococcus aureus by disc diffusion assay using tetracycline as a standard. Apart from that, the wound healing activity of a polyherbal formulation was evaluated by an incision model in Wistar rats. The results showed that the polyherbal formulation exhibited dark brown colour with a smooth texture and cinnamon-like odour. The gel showed 9% LOD, pH was found to be 7.5±0.3, viscosity was 4609.5± 13.44 cps at 10 rpm with spindle number 63, and spreadability was found to be 19.44±0.26 (g.cm/s), and no irritation was found on the healthy volunteer's skin. In the wound healing activity, polyherbal did not affect the normal feed and water uptake. The wound did not show any pus formation throughout the treatment period. In the Planimetry assessment, wounds treated with polyherbal formulation showed a good score at the end of the treatment. Results showed that polyherbal formulation containing 70% methanolic extract of C. asiatica leaves, methanolic extract of C. zeylanicum stem bark as well as oil of M. olifera seed have good wound healing activity.
Novel imidazole 2-amino pyrimidine deivatives: Insilico studies, evaluation of their anti-cancer activity against human-CDK2
Authors: OLETİ Navneetha , SATTU Hemalatha , SUNKARA Munı Sıreesha , KURELLA Pranitha , MANCHI Sahithi
Published: August 2023

In drug discovery process the identification of lead compounds by virtual screening is a novel approach. From the literature it is understood that imidazoles and pyrimidines have gained much importance among the medicinal chemists because of their flexible structure and varied pharmacological activities. In present study imidazole and 2-amino pyrimidine derivatives were designed, subjected to the structure based virtual screenings in order to find the novel anticancer agents against human CDK2 protein. The molecular properties and molecular toxicity prediction was done using various online softwares like Molinspiration, Molsoft, OSIRIS, pkCSM along with bioactivity properties. The derivatives which exhibited drug like property were further subjected to molecular docking studies using Autodock Vina. Hits are identified, the basic pharmacophoric features responsible for the anticancer activity were predicted. Based on docking results the compound 24, which exhibited highest binding interaction with receptor will be further synthesized and can be novel lead for the development of anticancer agents.
UNDERSTANDING VACCINATION HESITATION FROM OBSERVATIONS OF FAMILY HEALTH CENTER WORKERS
Authors: DUACI Alişan , ŞAHİN Menduha , BABAOĞLU Ülken Tunga
Published: August 2023

Objective: Family health centers are the first place for healthcare providers and vaccine-hesitant parents who need information. Healthcare providers can play an important role in mitigating vaccine hesitancy by providing accurate information to parents. This study aims to determine the prevalence of vaccine hesitancy or refusal among parents encountered by healthcare workers in family health centers in Kırşehir, and to identify associated factors.

Method: The study population consisted of family health workers working in Family Health Centers at the Kırşehir Center (N=101). The data form used in the descriptive study was prepared by the researchers by reviewing the literature. The data were collected by aplying face-to-face question and answer technique during the visits of the researchers to the family health centers.

Results: When asked about the rate of vaccine hesitancy/refusal in the past year, 13.2% (n=10) reported that they had encountered it frequently, and 28.9% (n=22) reported that they had encountered it at least once. 61.8% (n=47) of the participants, reported that the socioeconomic level of families experiencing vaccine refusal was high. When the participants met with a parent who refused vaccination, 98.7% (n=75) stated that they would explain the necessity of vaccines and encourage them to receive them, and 1.3% (n=1) stated that they would respect this decision. 84.1% (n=64) stated that the family with vaccine hesitancy/refusal changed their decision after their information they provided. The most common reason given to the participants by families who were undecide or refusal vaccine was objections to the ingredients in the vaccine (mercury, thimerosal, etc.) with rate of 71.1% (n=54).

Conclusion: Vaccine ambivalence was found to be against all vaccines and the act of vaccination, not against a specific vaccine. It was observed that when families who were hesitant about vaccination were informed by healthcare proffessionals, their attitudes changed. For this reason, it is important that parents with vaccine hesitancy are adequately and accurately informed about vaccines. It is thought that regular trainings should be organized for both healthcare professionals and families on vaccination in Turkey and the health literacy level of the society should be increased.
THE RELATIONSHIP OF HOUSING STATUS, NUTRITIONAL HABITS AND FOOD CONSUMPTION WITH CONSTIPATION IN UNIVERSITY STUDENTS
Authors: SEREMET KÜRKLÜ Nilgün , ALOĞLU Bengi , ÜNAL Eda , ÇOŞKUN Melek , DEMİR Nisa , GÜDÜK Nüket
Published: August 2023

Objective: This study was conducted to investigate the relationship between university students' housing status (at home and in dormitory), eating habits and food consumption amounts with constipation.
Method: The study was conducted cross-sectionally with students (n=382) studying at Akdeniz University. Data including sociodemographic information and dietary habits of the participants were collected by face-to-face interview method using a questionnaire. Anthropometric measurements including height, body weight and waist circumference were taken and body mass index (BMI) was calculated. 24h dietary recall of the participants was taken by the researchers, and the Bristol defecation scale and constipation severity scale were used to evaluate the constipation status.
Results: The mean age of the participants was 21.5±1.48 years. The mean BMI was 21.9±3.38 kg/m2, and it was determined that about three quarters of them (75.0% female and 73.3% male) had normal BMI. In both groups, white bread, 1 serving of fruit or vegetables per day, and 1-2 servings of legumes and vegetable dishes per week were consumed predominantly. In general, approximately two-thirds of both home and dormitory students were found to have ideal colonic transit according to the Bristol Stool Scale and had a low constipation severity scale score. When individuals were evaluated according to the constipation pain scale, a significant difference was found between students living at home and dormitory (p<0.001). Although a significant difference was observed for saturated fatty acids and polyunsaturated fatty acids (p<0.05), no significant differences were found in the daily intake of other constipation-realated nutrients including dietary fiber, soluble and insoluble fiber.
Conclusion: Although both home and dormitory students had low fiber intake, the number of individuals with slow colonic transit was low. More studies are needed to evaluate the relationship between nutrition, lifestyle and constipation by including other factors affecting constipation.
Policy and implementation
Authors: Palmer James
Published: August 2023

Water policy must reflect national values and aspirations, but it is implemented regionally across the country, to an important extent by landowners. James, who until March, was Chief Executive of the Hawke’s Bay Regional Council, will discuss how the implementation conundrum looks to someone returning to central government after a spell in an important agricultural region – one recently devastated by floods.
Te Awa Tupua—ko te Awa te tuatahi, ko te Awa te tuarua
Authors: Tuaine Nancy
Published: August 2023

In 2017 for the first time in Aotearoa New Zealand a river was granted legal recognition. This recognition included a set of values, Tupua Te Kawa which now guide the way in which decisions are made across the Whanganui River catchment. For this reason, Te Awa Tupua (the Whanganui River Claim Settlement) provides one of the most striking departures in water governance this century in recent history. In this seminar, Nancy will talk about Te Awa Tupua and what we can learn from its approach.
The Role of Errors in Fallibilist Theories of Knowledge
Authors: Golden Dániel
Published: August 2023

Fallibilism in epistemology is the view that we as human beings can never be in the position of acquiring ultimate truth, there is always a chance for discovering that we were in error. Nevertheless, fallibilists are not sceptics: they still stick to the idea that we are always in the position of holding a set of temporary truths, prevalent until the moment of getting denied and replaced by a better or more attractive candidate. On the other hand, fallibilists do side with the sceptics in their opposition to dogmatics, since they do not find compelling closed systems of knowledge, as they plea constantly for genuinely new insights.

According to the presented fallibilist models of knowledge, trials are necessary steps in acquiring new knowledge; there is no growth of knowledge without exercising the practice of trial and error. Errors are the necessary components of the procedure, since the usability of deductive and inductive methods getting to necessary truths in real life are strongly limited. In practice alternative strategies, like abductive reasoning, are coming to the front in our pursuit for maintainable propositions.
Análisis genético de un ensayo de progenies de ulmo (Eucryphia cordifolia) en un sitio degradado de la región de Los Ríos, Chile.
Authors: Ipinza Carmona Roberto , Ortega Zúñiga Alicia , Molina Brand María
Published: August 2023

Se evalúan las mediciones anuales de altura, hasta los 47 meses de edad, de plantas de 9 progenies de ulmo (Eucryphia cordifolia) incluidas en un ensayo de métodos de plantación establecido en tres quilantales del predio Pumillahue en la comuna de Mariquina en la región de los Ríos.  Se calculan los valores medios de altura a cada edad y se determinan valores de heredabilidad y correlaciones fenotípicas y genéticas entre las alturas medidas a diferentes edades. Se identifican familias de crecimiento sobresaliente, especulándose respecto a su eventual propagación clonal y recomendando continuar el estudio hacia edades más avanzadas.
Crecimiento y supervivencia de cinco especies nativas en un ensayo de plantación con consideraciones genéticas, en bosque siempreverde estructuralmente alterado.
Authors: Gutierrez Caro Braulio
Published: August 2023

Se analizó una medición de altura y supervivencia, al tercer año de crecimiento en terreno, de un ensayo de plantación de cinco especies nativas: ulmo (Eucryphia cordifolia) y lingue (Persea lingue) a nivel de progenies, y tepa (Laureliopsis philippiana), roble (Nothofagus obliqua) y olivillo (Aextoxicon punctatum) como grupos diversos representativos del bosque local. Todas ellas plantadas en fajas habilitadas en quilantales de un bosque siempreverde severamente degradado en la provincia de Valdivia, Chile. Con los datos de la medición se efectuó el análisis descriptivo del ensayo y una evaluación estadística usando análisis de varianza y pruebas de comparación múltiple (Tuckey), para evaluar el efecto de la densidad de plantación y de la proporción de especies intolerantes/tolerantes sobre el crecimiento y supervivencia de las plantas, para un nivel de significancia de 0,05%. Se concluye que el ensayo presenta en general una alta supervivencia (86,4%). Las plantas se encuentran creciendo activamente, observándose mayor altura en las intolerantes o pioneras que en las tolerantes. No se observó efecto de los tratamientos sobre la supervivencia (p-value > 0,05), pero se detectan diferencias significativas de altura particularmente para roble y olivillo. En general los tratamientos con mayor proporción de especies pioneras intolerantes, mostraron significativamente más crecimiento que aquellos en que estaban en igual proporción (p-value = 0,0003). En cualquier caso, las evaluaciones son tempranas por lo que es necesario conservar y hacer labores de mantención del ensayo para continuar con evaluaciones en estados de desarrollo más avanzados.
The Determinants of Central Bank Efficiency Scores: The Case of Tunisia
Authors: Ines Abdeltif Andrea , Faiza Bouhouch , Daly Lamia
Published: August 2023

The global financial crisis of 2007 and the recent health crisis of 2019 revealed the inefficiency of the pure status of central banks. They have also prompted reflection on the question of a new "central banking". If the challenge for academic work is to redraw the theoretical contours, it is rather a question for central bankers to redefine the new framework of their action. In this sense, abundant literature has emerged examining the institutional arrangements most likely to make central banks effective. On the other hand, and to our knowledge, few analyses have focused on delineating a new intermediate status that would allow central banks to be more efficient.It is in this perspective of research on the efficiency of central banks that our article is written. The latter is an evaluation of the evolution of the efficiency scores of the Central Bank of Tunisia (BCT) with the change of its status, over the period from 2000 to 2020. The first part of the paper is a review of the theoretical and empirical literature on the issue of measuring central bank efficiency. In the second part, we propose to calculate and interpret the evolution of the BCT's efficiency, with its change of status.The calculation of the efficiency scores leads to an average score of 0.765 and also reveals frequent changes in scores and alternating periods of increase and decrease. Our economic analysis, split into two periods before and after the BCT's independence, allows us to show that the efficiency scores recorded are not linked to its status, but rather are explained by macroeconomic, financial, monetary, and institutional variables.
Sexual Haunting in Randall Kenan’s “Cornsilk”
Authors: Harris Trudier
Published: August 2023

Breaking with traditional representation in African American literature, Randall Kenan portrays raw sexuality in “Cornsilk” in a brother’s romantic engagement with his sister over two years. Previous writers touched gingerly upon sexuality with Black characters, but Kenan foregrounds it. In so doing, he fills a gap in representation that has been visible for decades, yet the story has received little scholarly attention, a fact that needs redressing in serious literary studies.
Disputing Historical Invisibility: Cherokee Removal and Barbara Kingsolver’s “Homeland”
Authors: Fraser Sarah
Published: August 2023

Barbara Kingsolver first story in her only volume of short fiction set the spectrum of values for her entire career. It deals with place and family, their sense of belonging, and the history of her Cherokee ancestors. Central to the plot is the issue of identity formation in the conflict between her people and the dominant culture. The commercialization of Native culture has created a artificial picture of the tragic reality of the removal of this society from their ancient lands.
Analysis of CBDC Narrative OF Central Banks using Large Language Models
Authors: Alonso-Robisco Andres , Manuel Carbo Jose
Published: August 2023

Central banks are increasingly using verbal communication for policymaking, focusing not only on traditional monetary policy, but also on a broad set of topics. One such topic is central bank digital currency (CBDC), which is attracting attention from the international community. The complex nature of this project means that it must be carefully designed to avoid unintended consequences, such as financial instability. We propose the use of different Natural Language Processing (NLP) techniques to better understand central banks’ stance towards CBDC, analyzing a set of central bank discourses from 2016 to 2022. We do this using traditional techniques, such as dictionary-based methods, and two large language models (LLMs), namely Bert and ChatGPT, concluding that LLMs better reflect the stance identified by human experts. In particular, we observe that ChatGPT exhibits a higher degree of alignment because it can capture subtler information than BERT. Our study suggests that LLMs are an effective tool to improve sentiment measurements for policy-specific texts, though they are not infallible and may be subject to new risks, like higher sensitivity to the length of texts, and prompt engineering.
Use of econometric models for solvency analysis and estimation of probability of bankruptcy of the enterprise
Authors: Пугачева Ольга
Published: August 2023

The article is devoted to the analysis of modern approaches to assessing the solvency and probability of bankruptcy of the enterprise using econometric models. An example of building an econometric model based on the national methodology for analyzing the solvency of a business entity is given
Evolution of legislation on the consolidated accounts of financial-industrial groups
Authors: Curagău Natalia , Popovici Angela
Published: August 2023

The current legislation establishes the conditions for the creation, state registration, operation and liquidation of financial and industrial groups, the rights and obligations of their members, and also ensures the protection of the rights and legitimate interests of members of financial and industrial groups, including regulating the aggregation and presentation of information about the companies of the group in consolidated financial statements. The company that controls the financial and industrial group is liable for its obligations with all property belonging to it on the basis of property rights and is not responsible for the obligations of the members of the financial and industrial group. The specifics of the responsibility of the parent organization and members of the financial and industrial group are established in the agreement on the creation of the group.
Aspects of accounting and taxation of donated goods sent fee of charge
Authors: Bulgaru Veronica
Published: August 2023

For the support and social protection of different categories of legal persons or individuals, as well as for the promotion of goods and services, entities offer free goods, services and cash. Depending on the type and purposes of the donation, their accounting and tax treatment differ. Although some theoretical and practical aspects of these operations are examined in the works of some local scientists, they do not fully address the particularities of accounting and presentation in tax reports of operations of assets free transfer. Therefore, the purpose of the study is to exhaustively disclose the content, manner of evidence and declaration of donation operations of various goods. The methodological basis of the research was the dialectical method of knowing the matter with its main components: analysis, synthesis, the reciprocal connection between primary and secondary, the manifestation of the particular in general, etc. The study made it possible to highlight through the prism of normative and legislative acts the aspects of accounting and taxation of assets donated and transmitted free of charge by types of recipients.
Issues of development of accounting systems of innovative economy
Authors: Щербатюк Василий
Published: August 2023

Some topical problems of the development of foreign (ukrainian) accounting, including its social and managerial aspects, are presented. The objective necessity of accounting accounts is substantiated, their deep and comprehensive characteristics are given. For the first time, the existence of an important problem of the structure of accounts was established and noted, and its solution was proposed. Presented are the exact (correct) definitions of active and passive accounts, the general scheme of accounts on them, vertical and horizontal types of accounts, a unified procedure for determining their balances at the end of the reporting period and important information of a historical nature. Proposals were made for the improvement and use of accounting accounts in the modern conditions of the development of an innovative economy.
Effects of integrated reporting in the stajeholder communication process
Authors: Cojocaru Ana-Carolina , Mihailă Svetlana , Grosu Veronica
Published: August 2023

Financial and non-financial reporting has been the primary means of communication between the firm and its stakeholders from its inception. Over the years, businesses and organizations have evolved to meet the everchanging demands of the commercial and social environment. The integration and reciprocal connection of both financial and non-financial data is now the final link in the evolution of reporting. Integrated reporting is undoubtedly a significant step forward in the evolution of corporate reporting; nonetheless, it is critical to examine if stakeholders' information demands are sufficiently met and whether they will function as a universal communication tool for businesses and their stakeholders. The purpose of this study is to identify and assess the benefits and drawbacks of using integrated reporting as a tool for communicating with stakeholders. The examination of the literature, comparative analysis, as well as induction and deduction are the research methods utilized to attain the specified aim.
The impact of the quality characteristics of the financial-accounting information on financial control and decision-making
Authors: Rotaru Daria
Published: August 2023

In recent decades, due to economic progress the role of accounting information has increased significantly, affecting more and more user’s behaviour in the process of making business decisions. Thus, the decision-making process must be supported by an adequate informational system able to reflect the real activity of the entity expressed in comparable, relevant, accurate, verifiable, timely and understandable figures. The efficiency of the entity’s future strategy is directly influenced and estimated based on accounting financial information, affected by the qualitative characteristics which evolved during the history of accounting. The use of accounting information quality, promote an efficient deployment of existing conditions of business. The study aims to operationalize financial reporting quality in terms of the qualitative characteristics as well as to investigate their influence on the financial control and decision making process.
Generating of hamilton full favoring apportionments
Authors: Bolun Ion
Published: August 2023

Aspects of full favoring of small beneficiaries in apportionments using Hamilton method are discussed. For this purpose, the requirements of full favoring Hamilton apportionments were defined and the AHS algorithm for determining such apportionments is described. Then, calculations which confirm the opportunity of using the AHS algorithm in this aim were performed.
The role of RPO and RTO in disaster recovery planning
Authors: Zgureanu Aureliu
Published: August 2023

As multiple research and surveys published in recent years show, disaster recovery is becoming an increasingly important factor in business continuity. Renowned British information provider IHS Markit states that organizations experience an average of 5 downtime events per month which is equivalent to 27 hours. This turns into significant losses or even leads to business closure. Careful disaster recovery planning is required to reduce losses, and two of the most important attributes used to measure the efficiency of the data protection and recovery process are the recovery time objective (RTO) and the recovery point objective (RPO). Based on the analysis of some recognized technical disaster recovery solutions, their related documentation and some publications of important specialists in the field, this article emphasizes the role of RTO and RPO in disaster recovery planning. As a result of the research, the place of RTO and RPO in information disaster recovery was highlighted, as well as the key elements in the calculation process of these two strategic recovery objectives.
Mathematical methods for evaluating the effectiveness of it investment projects
Authors: Ghetmancenco Svetlana
Published: August 2023

In order to ensure the long-term financial stability of investment projects, it is necessary to use mathematical models. Mathematical models allow the optimization of decisions in strategic investment management. There are examined mathematical models that can be used in determining the efficiency of investment projects in computerization.
Management of sales on banking products at Romanian commercial bank
Authors: Oancea Negescu Mihaela Diana , Buzoianu Ovidiu Andrei Cristian , Guţu Corneliu , Sarbu Maria Alexandra
Published: August 2023

A study on sales management was inspired by reality, taking into account the fact that modern companies have it as an essential function. In this context, the sales activity and its management have acquired their essential role in the activity of a competitive company. The present study thus starts from the idea that sales means a vital problem for companies, a problem that must be solved through an appropriate approach. We are practically witnessing a transition from a transactional to a relational attitude. The present study proposes for analysis a topic intensely discussed in almost all media in Romania. The services segment is a basic lever of the economy and also the most difficult area to follow from a fiscal point of view, precisely due to the diversity that marks this segment of activity. Over time, the services have undergone numerous changes, both from a legislative and organizational point of view, both nationally and internationally. Services currently tend to encompass broader categories of domains, targeting all social and age classes. The different levels of training, as well as the vast aspect of the professions involving the provision of services, have contributed decisively to the development of this segment in the second area of interest in the contemporary world after the production segment. Sales management is important for meeting customer needs and ensuring the quality of services provided.
Ways of growth of revenue of the public national budget In the Republic of Moldova
Authors: Sviridenco Lidia
Published: August 2023

At the present stage of development of our country, there is a need to improve the level of economic stability. One of the links that can ensure this phenomenon is the public national budget, namely the optimization of revenues and expenditures in it, because they ensure the social and economic development of the Republic of Moldova and its regions. The public national budget deficit has been observed in the Republic of Moldova for several years in a row, which indicates a lack of revenues to cover all expenditures. Therefore, it is necessary to direct all efforts to find sources of growth of its revenues and their rational use.
The evolution of global financial imbalances in conditions of pandemic crisis
Authors: Luchian Ivan , Filip Angela
Published: August 2023

Global imbalances combine all forms of relations between different elements of the world economy, which have a certain negative impact, ie they bring some negative consequences for the global economy as a whole or for certain regions and countries. Based on the recognition of their existence and their interconnection through different transmission channels, the Generalized Model of Global Imbalances Synergy was elaborated by authors Kovalev and Paseko, which in our opinion could be adjusted to the current situation. The application of this model makes the onset of new financial crises predictable. The purpose of this research was to test this hypothesis. Research on the applicability of the mentioned model started from the works of Model’s authors and continued by examining of international financial institutions reports, statistical reports published on the Internet, as well as analyses of experts in this field from different countries. The International Monetary Fund specialists’ works confirm, to a certain extent, the viability of nominated model. The research carried out allows highlighting of some global imbalances in the context of the COVID-19 crisis. It is about global monetary imbalances, imbalance between income and consumption in certain categories of countries, the imbalance between the size of world economy and global debt, the imbalance between the excess liquidity and investment mechanisms functioning. The pandemic crisis in turn contributed to creation of new global imbalances of anti-crisis economic and financial measures. It must be mentioned the discrepancy between developed and developing countries through the prism of economic-financial intervention as anti-crisis measures. However, undertaking these activities require the attracting of additional funds, which in itself generates new problems. The results of conducted research allow drawing certain conclusions regarding current trends in the functioning of global financial mechanisms and their impact on financial market in the Republic of Moldova.
SEVERE CORONAVIRUS INFECTIONS IN PREGNANCY: A SYSTEMATIC REVIEW
Authors: Putri Nurfauzia Yunike
Published: August 2023

Introduction: A systematic literature review was undertaken to examine case reports pertaining to Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome coronavirus (SARS-CoV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, in the context of pregnancy.

Objective: The objective was to provide a comprehensive overview of the clinical manifestations, disease progression, and outcomes for both pregnant individuals and their neonates.

Methods: A comprehensive search was conducted on the MEDLINE and ClinicalTrials.gov databases, covering the period from their establishment up until August 3, 2023. The author incorporated articles that present case-level data about the infection of pregnant women with MERS-CoV, SARS-CoV, and SARS-CoV-2. The course of sickness, markers of severe disease, maternal health outcomes, and pregnancy outcomes were extracted from the articles that were included.

Results: A total of 1,328 distinct publications were found, with 1,253 articles being removed based on the evaluation of their titles and abstracts. A comprehensive examination was conducted on a total of 75 publications, out of which 29 papers were deemed ineligible and hence eliminated from the analysis throughout the full-text review process. Out of the 46 papers that provided case-level data, eight publications presented information on 12 instances of MERS-CoV infection, seven publications discussed 17 cases of SARS-CoV infection, and 31 publications detailed 98 cases of SARS-CoV-2 infection. The clinical presentation and progression of the illness varied over a spectrum, ranging from individuals who showed no symptoms to those who experienced severe and ultimately deadly disease. This pattern was consistent with what is typically observed in the broader population of patients. The occurrence of significant morbidity and mortality in women who contract MERSCoV, SARS-CoV, or SARS-CoV-2 during pregnancy has been documented. Adverse pregnancy outcomes such as pregnancy loss, preterm delivery, and laboratory findings indicating vertical transmission have also been recorded.

Conclusion: The available data on SARS-CoV, MERS-CoV, and SARS-CoV-2 infections during pregnancy are currently inadequate. However, these data can still provide valuable insights for informing early public health interventions and clinical decision-making in the context of COVID-19. It is important to note that more comprehensive and systematically gathered data are needed to further enhance our understanding of this topic.
ONE- STEP COMPARED WITH TWO-STEP GESTATIONAL DIABETES SCREENING AND PREGNANCY OUTCOMES : A SYSTEMATIC REVIEW
Authors: Putri Nurfauzia Yunike
Published: August 2023

Background: Carbohydrate disorders, including gestational diabetes mellitus (GDM) and pregestational diabetes, have significant impacts on maternal, fetal, and neonatal health.

Aim: This study aims to conduct a systematic review and analyze pooled data to evaluate how the choice of GDM testing strategy influences pregnancy outcomes.

Methods: This systematic review adhered to the PRISMA guidelines. The study question and eligibility criteria were defined using the PICOT method, focusing on pregnant patients and comparing IADPSG one-step to Carpenter-Coustan two-step testing in the late mid-trimester

Results: Three randomized controlled trials (RCTs) were included, involving a total of 2,333 participants. The one-step approach demonstrated a non-significant difference in GDM incidence compared to the two-step approach. However, the one-step approach was associated with significantly improved maternal and perinatal outcomes

Conclusion: This systematic review provides insights into the comparison of One Step versus Two Step approaches for gestational diabetes screening and their impact on maternal and perinatal outcomes. While the incidence of GDM did not significantly differ between the two approaches
PREVALENCE OF DEPRESSION OR ANXIETY DURING ANTEPARTUM HOSPITALIZATIONS FOR OBSTETRIC COMPLICATIONS : A SYSTEMATIC REVIEW
Authors: Putri Nurfauzia Yunike
Published: August 2023

Introduction: Women with pregnancy problems are more likely to develop perinatal mood disorders or relapse into underlying mood disorders. 

Objective: This study aimed to look at the prevalence of prenatal depression and anxiety in women admitted to an antepartum ward for obstetric problems. 

Methods: We searched Pubmed, Embase, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsycINFO, and ClinicalTrials.gov for English-language papers published between establishing the database in July 2023. The cross-sectional, cohort, case-control, quasi-experimental, and randomized-controlled designs used in the selected studies were all related to the research goal. 

Results: We discovered 8.799 papers and reviewed 7.918, included in the primary outcome systematic review. Using a 14-question checklist is used to assess the quality of each study. Depression was 34% (95% CI 27-41%), while anxiety was 29% (95% CI 16-43%). Significant clinical and methodologic heterogeneity between trials was expected, and it persisted even after planned a priori subgroup analysis and meta-regression. Nonetheless, the effect direction was constant across trials. There was no evidence of publication bias. 

Conclusion: According to the current systematic review, one in every three pregnant women hospitalized for obstetric difficulties has clinical depression or anxiety symptoms, double the reported prevalence of prenatal depression or anxiety in the general obstetric population.
Kültür Kavramı ve Müslüman Toplumun Kültür Sorunu
Authors: ADIGÜZEL Muhammet Metin , KOYUNCU Ahmet Ayhan
Published: August 2023

Batılı bir kavram olan kültür çeşitli anlam katmanlarından geçerek günümüzde nihai karşılığını toplumun yaşam tarzı ifadesinde bulmuştur. Aydınlanma ve modernite süreci ile birlikte Batı dünyası seküler bir yaşam tarzı geliştirerek kültürü metafizik bağlarından koparıp maddi bir zemine oturtmuştur. 1950 sonrası dönemde bazı eleştirilerle karşı karşıya kalan modernite yerini postmoderniteye bırakırken, kültür kavramı da postmodern bir anlayış paralelinde kültürel çoğulculuk söylemine bağlanmıştır. Batı dünyasında mevcutta karşılığı olan bir kültürel süreç yaşanırken, Müslüman toplum geleneksel din anlayışını mutlaklaştırmakla mevcut şartlara yabancılaşmış ve bir kültür, bir yaşam tarzı geliştirememiştir. Geleneği taklitten ileri gelen denge bozucu durum kimi noktalarda Batı dünyasını taklitle aşılmaya çalışılsa da sorun daha da derinleşmiştir. Makale, kültür kavramına yönelik betimsel bir araştırmadır. Kültür kavramının tarihsel arka planı, Batı dünyasındaki kültürel dönüşüm ve Müslüman dünyasının kültür kavramına yaklaşımı analiz edilmeye çalışılmıştır. Müslüman toplumun alternatif bir modernite geliştirme yeteneği kültürel gelişimine bağlıdır. Müslüman toplum yenilik hareketlerinde teorik tasarımlara bağlı kalmış, kültürün önemini göz ardı etmiştir. Çalışma, kültür sahibi olmanın önemine dikkati çekmesi açısından önem arz etmektedir. Araştırma, hissedilen ancak tanımlanması zor olan sıkıntıyı kültürel kriz olarak tanımlamaktadır. Krizin aşılmasının eğitim, dini yorum ve pratik yaşam arasındaki uyumla sağlanabileceği sonucuna varmaktadır.
Sicill-i Ahvâl Defterlerine Göre Osmanlı Bürokrasisinde Görev Yapan İşkodralı Devlet Memurları
Authors: ATABAY Ahmet Murat
Published: August 2023

Sicill-i Ahvâl Komisyonu, 1879 senesinde Osmanlı Devlet Kurumlarında sayıları 35.000’i bulan memurların özgeçmişlerini ve işyerlerindeki çalışma durumlarını tespit etmek ve bu memurları denetlemek amacıyla II. Abdülhamid zamanında kurulmuştur. Memurlar hakkında tutulan bu defterlere de Sicill-i Ahvâl denilmektedir. 1879-1909 yılları arasında tutulan bu defterler bugün Türkiye Cumhuriyeti Cumhurbaşkanlığı Devlet Arşivleri Başkanlığı Osmanlı Arşivinde bulunmaktadır. 201 defterden oluşan ve toplamda da 56.652 memur hakkında tutulan bu kıymetli veriler çalışmamızın ana kaynağını oluşturmaktadır. Yaptığımız araştırma neticesinde İşkodra’da doğan memurlara ait 241 kayıt tespit edilmiştir. Bu çalışma ile İşkodra doğumlu memurların sosyal statüleri, ekonomik ve eğitim durumları hakkında çeşitli veriler elde edilmiş olup o dönemdeki memurların söz konusu durumları aydınlatılmaya çalışılmıştır
Evaluation of the in vivo and in vitro effect of Libidibia ferrea on Leishmania (Leishmania) amazonensis
Authors: De Jesus Bacha Thiago , Bezerra Jensen Bruno , Silva de Jesus Amanda , Torres Iwabuchi Pamela Emily , Cardoso Rodrigues dos Santos Geraldi Katia Solange , Gomes Pinheiro Francimeire , Kima Peter , Ramos Franco Antonia Maria
Published: August 2023

Currently, the therapeutic arsenal available for the treatment of leishmaniasis is limited. Thus, the aim of this study was to evaluate the in vitro and in vivo antileishmanial efficacy of the methanolic extract and dichloromethane fraction of Libidibia ferrea (DCM). To achieve this goal, the cytotoxicity of these extracts was determined in in vitro assays. Subsequently, its effects on a Leishmania (Leishmania) amazonensis infection of macrophages were evaluated. In vivo studies were performed with golden hamsters infected with L. (L.) amazonensis, which were treated with a microemulsion containing DCM. Furthermore, this fraction was also evaluated in combination with Glucantime®. The extracts reduced macrophage infections and induced reversal of IL-6 suppression in infected cells. There was a significant reduction in the volume of the lesion in the animals treated intralesionally with the combination of DCM+20 mg/SbV/kg/day. Taken together, the results obtained show that L. ferrea extracts (DCM) were not cytotoxic to macrophages and limited macrophage infection. The microemulsion containing the dichloromethane fraction of L. ferrea enhanced the curative effects of Glucantime®
Los cañones de La Sabana y la patrimonialización en contextos afrodescendientes de Venezuela
Authors: Altez Yara , Páez Leonardo
Published: August 2023

Este artículo sintetiza la experiencia de activación patrimonial de unas antiguas piezas de artillería sumergidas en la costa central de Venezuela, producto de un naufragio en las inmediaciones marinas de una comunidad afrodescendiente llamada La Sabana. Las piezas fueron sustraídas para su comercialización fraudulenta y a partir de ese momento, antropólogos, instituciones públicas venezolanas y la propia comunidad, se involucraron en un proceso de activación patrimonial. El caso permite comprender algunas características de la patrimonialización en la Venezuela contemporánea. Palabras Clave: patrimonio cultural, comunidad, afrodescendientes, Venezuela.
ANÁLISE COMPARATIVA DO VPM AUTOMATIZADO COM A MICROSCOPIA UTILIZANDO O ANALISADOR NIHON KOHDEN CELLTAC G
Authors: JAEGER Gregory , ZiITTEL Luis Fernando , GASPARELO Maicon Adriano , GREGÓRIO Paulo Cézar , HENNEBERG Railson
Published: August 2023

Os parâmetros plaquetários avaliados pelos analisadores hematológicos, tem sido amplamente utilizado, principalmente para correlacionar o volume plaquetário médio (VPM) com situações clínicas que envolvem o aumento do tamanho das plaquetas. O objetivo deste estudo foi comparar os valores do VPM liberados pelo analisador Nihon Kohden Celltac G modelo MEK 9.100 com a avaliação do tamanho das plaquetas em extensões sanguíneas. Foram avaliados dados de 400 hemogramas de pacientes saudáveis ou em acompanhamento terapêutico ambulatorial. As amostras foram divididas em dois grupos: (i) VPM normal (7 a 11fL) (n=200) e (ii) VPM acima do intervalo de referência (> 11 fentolitro (fL)) (n=200). A análise do VPM e a confecção da lâmina foram realizadas em até 2 horas após a coleta. Foram contadas 100 plaquetas por lâmina e classificadas de acordo com a porcentagem de macroplaquetas e plaquetas gigantes encontradas. O intervalo de valores do VPM no grupo estudado foi de 7,6 e 16,3 fL (10,6 ± 1,6). No grupo (i), 92% das extensões sanguíneas não apresentaram alterações plaquetárias; em 10 amostras a alteração encontrada foi classificada como discreta e apenas 1 lâmina apresentou a presença de macroplaquetas. No grupo (ii), 134 amostras foram classificadas pela presença de macroplaquetas; 17 amostras apresentaram tanto macroplaquetas quanto plaquetas gigantes e 32 lâminas foram classificadas como presença discreta. Apenas 8% das amostras (n=16) com VPM alto foram classificadas como ausente. Os resultados indicam que há correlação entre o VPM e a presença de alterações de tamanho das plaquetas quando a mesma é realizada de forma padronizada. Palavras-chave: Volume plaquetário médio, Plaquetas, Macroplaquetas, Plaqueta gigante, Nihon Kohden Celltac G.
ANÁLISE DE PARÂMETROS DE POTABILIDADE DA ÁGUA PARA CONSUMO HUMANO OBTIDA DE BEBEDOUROS
Authors: ADAM Isadora Padilha , OLIVEIRA Cristiane Da Silva Paula de
Published: August 2023

A água é um recurso essencial à vida e tem papel fundamental no funcionamento do organismo humano. Porém, pode conter microrganismos patogênicos e se tornar um veículo para transmissão de doenças. Por isso, a água destinada ao consumo humano deve seguir um padrão de potabilidade, que é atualmente estabelecido pela Portaria Nº 888, de 4 de maio de 2021. Para atender ao padrão exigido, a água passa por processos de tratamento e sua qualidade é avaliada através de parâmetros físico-químicos, organolépticos e microbiológicos, que devem ser monitorados periodicamente ao longo da rede de distribuição e nos pontos de consumo. O objetivo deste trabalho é analisar os parâmetros físico-químicos de potabilidade da água de bebedouros de uma instituição de ensino localizada na cidade de Curitiba, Paraná. Os parâmetros analisados foram cloro residual livre, pH, cloretos e dureza total, de acordo com os métodos descritos no Manual Prático de Análise de Água, da Fundação Nacional de Saúde. Os resultados obtidos demonstraram que três amostras não atenderam ao valor mínimo exigido de cloro residual livre (< 0,2 mg/L) e uma apresentou valor de dureza total acima do máximo permitido (> 300 mg/L CaCO3), enquanto os demais resultados estavam de acordo com o estabelecido pela Portaria e com dados encontrados na literatura. É necessária a manutenção e higienização periódica dos bebedouros, que podem influenciar a qualidade da água disponível para consumo por serem potenciais fontes de contaminação.
Brief reflection on ageing, public policies, and social work intervention
Authors: Carvalho Helena
Published: August 2023

With the conception of the Welfare State in Portugal, although late compared to the other countries of the European Union, it was possible to agree to a series of measures that provided an aging process with the dignity that was once unthinkable. However, these measures cannot be watertight, and it is possible to verify the evolution of social policies over the years to allow for adaptation to the times and needs that arise. Alongside this evolution and these changes, we have been witnessing the adaptation by the Social Service to a new reality, arming itself with tools that accompany this evolution, and which are essential for the area of aging. Defying its own policies and measures, the social service stands out for its diagnostic capacity, allowing for an adequate intervention, seeking the most appropriate answers, respecting the elderly, the family, and the community itself.
The role of Activities of Daily Living in the empowerment process of people with disabilities
Authors: Ribeiro Duarte Sara Isabel , Teixeira Mónica , Dias Almeida Cristiana
Published: August 2023

The conceptual model of disability is based on the expression of limitations of a person's individual functioning in a social context that clearly represents a disadvantage for the subject himself. The importance of social inclusion and the promotion of the autonomy of people with intellectual disabilities are two crucial aspects of the intervention and, at the same time, they are conceptually interconnected. This synergy makes it possible to understand the connection between both and the importance that each one represents in the lives of people with intellectual disabilities. In this way, generically, inclusion confers the notion of belonging, equality and responsibility towards the other elements and, in turn, autonomy confers freedom of choice and the satisfaction of a personal desire. This conceptual exploration work has as its central objective, to emphasize the importance of the existence of integrated intervention in terms of maintenance and training of Activities of Daily Living and their constituents in people with intellectual disabilities. It is concluded that the achievement of overcoming the difficulties of individuals with intellectual disabilities integrates individual involvement supported by their personal networks and the mobilization of society.