bluuebunny/crossref_metadata_2025 huggingface dataset:
Using Response Surface for Searching the Nearly Optimal Parameters Combination of the Foam Concrete Muffler
Authors: Lin Teng-Hsuan , Deng Jyhjeng , Chen Yi-Ching
Published: November 2022

A car muffler is a device to improve car noise emission. Some conventional mufflers use layers of glass fiber as a material to absorb noise. However, filling glass fiber is an environmentally unfriendly work, mainly manually filling with chop strand fiber. This research selected a composite material of glass fiber and foam concrete to replace chop strand fiber to avoid this hazard and maintain the muffler’s good noise reduction performance. A response surface methodology with a two-way factorial experimental design repeated the center point twice is performed. The density of the foamed concrete and the weight of the glass fiber is being considered in order to determine the nearly optimal combination of the values in two factors. The response variable is the loudness sensation in Sone of the noise generated from the muffler. At present, the lowest loudness sensation from the two-way factorial design is 16.6494 Sones, which occurred for a muffler with a formula combination of a density of 0.2 g/cm3 and 40 g of glass fiber. The significance of this paper is the presentation of a new application of foam concrete to the green muffler design. To the best of our knowledge, this unique area has never been tackled in the material application of concrete. We have discovered that foam concrete indeed does an excellent job in terms of noise reduction as compared with that of a market muffler.
Mouldability of Additively Manufactured Attachments on Multipoint Tools
Authors: Herzog Thomas , Tille Carsten , Seitz Hermann
Published: November 2022

Enhanced multipoint moulding with additive attachments (EMMA) is a process combining vacuum-assisted multipoint moulding (VAMM) and additively manufactured moulding attachments for carbon fibre reinforced plastics (CFRP) component production. The aim of this initial study is to investigate the mouldability of the additively manufactured attachments on the multipoint tool. For this purpose, two different test specimens were defined, the VAMM machine was adjusted, the attachments were additively built with the robot on the curved silicone interpolation layer and lastly, the CFRP specimens were moulded. The fabrication results were analysed with surface comparisons to check that there was no displacement of the attachments during moulding. A visual evaluation of the manufactured components was carried out, and the overall dimensional accuracy was assessed by comparing the surface with the target geometry. The results showed a very good agreement between the shapes before and after the moulding and thus prove that the attachments were not postponed in the moulding process. The optical evaluation confirms good moulding results for the parts manufactured with the enhanced multipoint moulding with additive attachments. Moreover, the evaluation shows that the major parts of the specimens comply with the permissible tolerance of t = 6 mm defined in ISO 20457. To the authors’ best knowledge, this is the first study that has investigated the entire EMMA process and systematically proved the mouldability of the additively manufactured attachments on multipoint tools.
Erosion Resistance of Valve Core Surface Combined with WC-10Co-4Cr Coating Process under Different Pretreatments
Authors: Zhong Lin , Li Zhichao , Wang Guorong , He Haiyang , Wei Gang , Zheng Sijia , Feng Guihong , Xie Nana , Zhang Rongyao
Published: November 2022

The erosion of the valve core causes valve failure problems. Thus, a novel method to extend the erosion resistance of the valve was innovatively proposed, namely, nanosecond laser ablation micro-pits on the substrate surface and high velocity oxygen fuel (HVOF) spraying WC coating to extend the erosion resistance of the valve. The characterization and evaluation of the erosion resistance of the WC-sprayed coating after the pretreatment of the 3Cr13 substrate surface polishing/grit blasting/nanosecond laser ablation circular micro-dimple were conducted using the unit coupon erosion test of liquid–solid two-phase flow, followed by the test evaluation and analysis of the erosion resistance test of the WC coating after different pretreatments of the full-size valve core. Results showed that the micro-dimple pretreatment on the surface of the 3Cr13 substrate increased the contact area rate and bonding strength of the substrate and the WC coating. By taking erosion volume loss as the evaluation index, the erosion resistance of the micro-dimple pretreatment on the surface of the 3Cr13 substrate was increased by about 31.98% compared with that of the polishing pretreatment. Therefore, the new method of surface nanosecond laser texture pretreatment and HVOF-spraying WC coating can effectively improve the erosion resistance of the valve.
Polymeric Orthosis with Electromagnetic Stimulator Controlled by Mobile Application for Bone Fracture Healing: Evaluation of Design Concepts for Medical Use
Authors: Vilela Filipe Bueno , Silva Eduardo Serafim , de Lourdes Noronha Motta Melo Mirian , Oliveira Rochelly Mariana Pedroso , Capellato Patricia , Sachs Daniela
Published: November 2022

Background: The occurrence of bone fractures is increasing worldwide, mainly due to the health problems that follow the aging population. The use of additive manufacturing and electrical stimulators can be applied for bioactive achievements in bone healing. However, such technologies are difficult to be transferred to medical practice. This work aims to develop an orthosis with a combined magnetic field (CFM) electrostimulator that demonstrates concepts and design aspects that facilitate its use in a real scenario. Methods: A 3D-printed orthosis made of two meshes was manufactured using PLA for outer mechanical stabilization mesh and TPU for inner fixation mesh to avoid mobilization. A CFM stimulator of reduced dimension controlled by a mobile application was coupled onto the orthosis. The design concepts were evaluated by health professionals and their resistance to chemical agents commonly used in daily activities were tested. Their thermal, chemical and electrical properties were also characterized. Results: No degradation was observed after exposure to chemical agents. The CMF achieved proper intensity (20–40 µT). The thermal analysis indicated its appropriate use for being modelled during clinical assessment. Conclusion: An orthosis with a coupled electrostimulator that works with a combined magnetic field and is controlled by mobile application was developed, and it has advantageous characteristics when compared to traditional techniques for application in real medical environments.
Heuristic Optimization of a New Type of Prestressed Arched Truss
Authors: Partskhaladze Gaioz , Alcala Julian , Medzmariashvili Elguja , Chavleshvili Gocha , Surguladze Bichiko , Yepes Víctor
Published: November 2022

This paper represents new approaches for calculating, designing, and optimizing prestressed arched trusses with a tie member. Structural systems with long spans, such as trusses, beams, frames, etc., are subjected to a considerable/substantial risk of losing load-carrying capacity because of the different types of loads used. Some traditional design methods define the values of prestressing force in the tie member and internal forces in the truss elements to avoid this load capacity loss. However, the accuracy and limits of the determination of the forces are not necessarily known. The authors offer a new type of prestressed arched truss and some new approaches in the design and calculation process to solve these disadvantages. The study’s main objectives were to design an innovative and new geometric form of prestressed arched truss, which allows the development of high-value prestressing force, to optimize a new truss for reducing self-weight, increasing load-carrying capacity compared to its analogs. The force, stiffness matrix, and simulated annealing methods were used during the study. A new advance to the optimization of prestressed arched truss suggested by the authors reduces the self-weight and improves the load capacity of the truss by 8–17%, depending on the span.
Synthetic Sulfide Concentrate Dissolution Kinetics in HNO3 Media
Authors: Dizer Oleg , Karimov Kirill , Kritskii Aleksei , Rogozhnikov Denis
Published: November 2022

The nature of tennantite (Cu12As4S13), chalcopyrite (CuFeS2) and sphalerite (ZnS) particles’ mixture dissolution in nitric acid (HNO3) media was investigated in this study. The effects of temperature (323–368 K), HNO3 (1–8 mol/L) and Fe3+ (0.009–0.036 mol/L) concentrations, reaction time (0–60 min) and pyrite (FeS2) additive (0.5/1–2/1; FeS2/sulf.conc.) on the conversion of the minerals were evaluated. It has been experimentally shown that the dissolution of the mixture under optimal conditions (>353 K; 6 mol/L HNO3; FeS2/synt. conc = 1/1) allows Cu12As4S13, CuFeS2 and ZnS conversion to exceed 90%. The shrinking core model (SCM) was applied for describing the kinetics of the conversion processes. The values of Ea were calculated as 28.8, 33.7 and 53.7 kJ/mol, respectively, for Cu12As4S13, CuFeS2 and ZnS. Orders of the reactions with respect to each reactant were calculated and the kinetic equations were derived to describe the dissolution rate of the minerals. It was found that the interaction between HNO3 solution and Cu12As4S13, CuFeS2 and ZnS under the conditions investigated in this are of a diffusion-controlled nature. Additionally, the roles of Fe(III) in the initial solution and FeS2 in the initial pulp as catalysts were studied. The results indicated that the increase in Fe3+ concentration significantly accelerates the dissolution of the mixture, while the addition of FeS2 forms a galvanic coupling between FeS2, and Cu12As4S13 and CuFeS2, which also accelerates the reaction rate. The results of the study are considered useful in developing a hydrometallurgical process for polymetallic sulfide raw materials treatment.
Characterization of a Biocomposite of Electrospun PVDF Membranes with Embedded BaTiO3 Micro- and Nanoparticles
Authors: Almeida Sérgio D. , Silva Jorge C. , Borges João P. M. R. , Lança M. Carmo
Published: November 2022

Damage to bone tissue is a common health issue that tends to increase in severity with age and other underlying conditions. To take advantage of the piezoelectric effect on bone remodulation, piezoelectric materials can be used to fill patients bone defects. Polyvinylidene fluoride (PVDF) and barium titanate (BaTiO3) are both well-known polymeric and ceramic biomaterials, respectively, as well as piezoelectric at room temperature. To mimic the extracellular matrix, PVDF membranes were produced by electrospinning onto a rotating drum to promote the alignment of fibers and micro- and nano-sized tetragonal BaTiO3 particles were embedded into these membranes to try to enhance the piezoelectric response and, therefore, bioactivity. After defining the best deposition parameters to produce pure PVDF membranes, the same parameters were carried over for the embedded membranes and both were characterized, revealing that the proposed method for obtaining β-phase PVDF (the polymer phase with highest piezoelectric coefficient) through electrospinning is viable, producing fibers with coherent diameters and alignment. The presence of barium titanate conferred bioactivity to the membranes and caused a decrease in fibers’ diameter and in superficial charge density.
Preparation and Hepatoprotective Activities of Peptides Derived from Mussels (Mytilus edulis) and Clams (Ruditapes philippinarum)
Authors: Wang Qian , Liu Fu-Jun , Wang Xin-Miao , Zhao Guan-Hua , Cai Dong , Yu Jing-Han , Yin Fa-Wen , Zhou Da-Yong
Published: November 2022

Low molecular weight (<5 kDa) peptides from mussels (Mytilus edulis) (MPs) and the peptides from clams (Ruditapes philippinarum) (CPs) were prepared through enzymatic hydrolysis by proteases (dispase, pepsin, trypsin, alcalase and papain). Both the MPs and the CPs showed excellent in vitro scavenging ability of free radicals including OH, DPPH and ABTS in the concentration range of 0.625–10.000 mg/mL. By contrast, the MPs hydrolyzed by alcalase (MPs-A) and the CPs hydrolyzed by dispase (CPs-D) had the highest antioxidant activities. Furthermore, MPs-A and CPs-D exhibited protective capabilities against oxidative damage induced by H2O2 in HepG2 cells in the concentration range of 25–800 μg/mL. Meanwhile, compared with the corresponding indicators of the negative control (alcohol-fed) mice, lower contents of hepatic MDA and serums ALT and AST, as well as higher activities of hepatic SOD and GSH-PX were observed in experiment mice treated with MPs-A and CPs-D. The present results clearly indicated that Mytilus edulis and Ruditapes philippinarum are good sources of hepatoprotective peptides.
New Polyketides from a Hydrothermal Vent Sediment Fungus Trichoderma sp. JWM29-10-1 and Their Antimicrobial Effects
Authors: Lai Changrong , Chen Jiayi , Liu Jing , Tian Danmei , Lan Donghe , Liu Tongzheng , Wu Bin , Bi Hongkai , Tang Jinshan
Published: November 2022

Marine fungi-derived secondary metabolites are still an important source for the discovery of potential antimicrobial agents. Here, five new polyketides (1, 2, and 6–8) and seven known compounds (3–5 and 9–12) were obtained from the culture of the marine-derived fungus Trichoderma sp. JWM29-10-1. Their structures were identified by extensive spectrographic data analyses, including 1D and 2D NMR, UV, IR, and HR-ESI-MS. Further, the absolute configurations of new compounds were determined by circular dichroism (CD) spectrum and alkali-hydrolysis in combination with the in situ dimolybdenum CD method. Subsequently, the antimicrobial effects of these isolated compounds were assessed by examining the minimal inhibition concentration (MIC) with the broth microdilution assay. Compounds 1 and 2 exhibited potent antimicrobial activity against Helicobacter pylori, including multidrug-resistant strains, with MIC range values of 2–8 µg/mL. Moreover, compound 1 showed significant inhibitory effects on the growth of Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA), Enterococcus faecalis, and vancomycin-resistant Enterococcus faecium, which greatly threaten human health. This study demonstrates that chromone derivatives 1–2, especially for 1, could be potential lead compounds for the development of new antimicrobial agents and provides insight for future medicinal chemistry research.
The Relationship between Nrf2 and HO-1 with the Severity of COVID-19 Disease
Authors: Mihić Damir , Loinjak Domagoj , Maričić Lana , Smolić Robert , Šahinović Ines , Steiner Kristina , Viland Sven , Šerić Vatroslav , Duvnjak Mario
Published: November 2022

Nuclear factor erythroid 2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1) have significant roles in the development of a hyperinflammatory state in infectious diseases. We aimed to investigate the association of the serum concentrations of Nrf2 and HO-1 with the severity of COVID-19 disease. The study included 40 subjects with mild and moderately severe forms of the disease (MEWS scoring system ≤2). Twenty of the subjects had MEWS scores of 3 or 4, which indicate a severe form of the disease, and twenty subjects had a MEWS score of ≥5, which indicates a critical form of the disease. HO-1 and Nrf2 were measured using the commercially available Enzyme-Linked Immunosorbent Assay (ELISA). Subjects with the most severe form of COVID-19 (critically ill) had a lower concentration of Nrf2 that negatively correlated with the markers of hyperinflammatory response (CRP, IL-6, ferritin). This observation was not made for HO-1, and the correlation between Nrf2 and HO-1 values was not established. In the mild/moderate form of COVID-19 disease, Nrf2 was associated with an increased 1,25 dihydroxy vitamin D concentration. The results of this study show that Nrf2 has a role in the body’s anti-inflammatory response to COVID-19 disease, which makes it a potential therapeutic target.
Interleukin-6 and Outcome of Chronic Hemodialysis Patients with SARS-CoV-2 Pneumonia
Authors: Donati Gabriele , Gasperoni Lorenzo , Zappulo Fulvia , Scrivo Anna , Napoli Marianna , Di Filippo Federica , Cappuccilli Maria , Mancini Rita , La Manna Gaetano
Published: November 2022

Background and Objectives: Chronic hemodialysis (CHD) patients are at increased risk of SARS-CoV-2 infection and the related complications and mortality of COVID-19 due to the high rate of comorbidities combined with advanced age. This observational study investigated the clinical manifestations of SARS-CoV-2 infection in CHD and the risk factors for patients′ death. Materials and Methods: The study included 26 CHD patients with SARS-CoV-2 pneumonia detected by positive RT-PCR on nasopharyngeal swabs and high-resolution computed tomography at hospital admission, aged 71 + 5.9 years, 14 of which (53.8%) were male, 20 (77%) under hemodiafiltration, and 6 (23%) on standard hemodialysis, with a median follow-up of 30 days. Results: Simple logistic regression analysis revealed that the factors associated with a higher risk of death were older age (OR: 1.133; 95%CI: 1.028–1.326, p = 0.0057), IL-6 levels at admission (OR: 1.014; 95%CI: 1.004–1.028, p = 0.0053), and C-reactive protein (OR: 1.424; 95%CI: 1.158–2.044, p < 0.0001). In the multiple logistic regression model, circulating IL-6 values at admission remained the only significant prognosticator of death. The ROC curve indicated the discriminatory cut-off value of 38.20 pg/mL of blood IL-6 for predicting death in chronic hemodialysis patients with SARS-CoV-2 pneumonia (sensitivity: 100%; specificity: 78%; AUC: 0.8750; p = 0.0027). Conclusions: This study identified a threshold of IL-6 levels at hospital admission for death risk in CHD patients with SARS-CoV-2 pneumonia. This might represent a valuable outcome predictor, feasibly better than other clinical, radiological, or laboratory parameters and preceding the IL-6 peak, which is unpredictable.
Glutathione Transferase P1: Potential Therapeutic Target in Ovarian Cancer
Authors: Simic Petar , Pljesa Igor , Nejkovic Lazar , Jerotic Djurdja , Coric Vesna , Stulic Jelena , Kokosar Nenad , Popov Dunja , Savic-Radojevic Ana , Pazin Vladimir , Pljesa-Ercegovac Marija
Published: November 2022

Chemotherapy resistance of ovarian cancer, regarded as the most lethal malignant gynecological disease, can be explained by several mechanisms, including increased activity of efflux transporters leading to decreased intracellular drug accumulation, increased efflux of the therapeutic agents from the cell by multidrug-resistance-associated protein (MRP1), enhanced DNA repair, altered apoptotic pathways, silencing of a number of genes, as well as drug inactivation, especially by glutathione transferase P1 (GSTP1). Indeed, GSTP1 has been recognized as the major enzyme responsible for the conversion of drugs most commonly used to treat metastatic ovarian cancer into less effective forms. Furthermore, GSTP1 may even be responsible for chemoresistance of non-GST substrate drugs by mechanisms such as interaction with efflux transporters or different signaling molecules involved in regulation of apoptosis. Recently, microRNAs (miRNAs) have been identified as important gene regulators in ovarian cancer, which are able to target GST-mediated drug metabolism in order to regulate drug resistance. So far, miR-186 and miR-133b have been associated with reduced ovarian cancer drug resistance by silencing the expression of the drug-resistance-related proteins, GSTP1 and MDR1. Unfortunately, sometimes miRNAs might even enhance the drug resistance in ovarian cancer, as shown for miR-130b. Therefore, chemoresistance in ovarian cancer treatment represents a very complex process, but strategies that influence GSTP1 expression in ovarian cancer as a therapeutic target, as well as miRNAs affecting GSTP1 expression, seem to represent promising predictors of chemotherapeutic response in ovarian cancer, while at the same time represent potential targets to overcome chemoresistance in the future.
Determination of Elastic Parameters of Lipid Membranes with Molecular Dynamics: A Review of Approaches and Theoretical Aspects
Authors: Pinigin Konstantin V.
Published: November 2022

Lipid membranes are abundant in living organisms, where they constitute a surrounding shell for cells and their organelles. There are many circumstances in which the deformations of lipid membranes are involved in living cells: fusion and fission, membrane-mediated interaction between membrane inclusions, lipid–protein interaction, formation of pores, etc. In all of these cases, elastic parameters of lipid membranes are important for the description of membrane deformations, as these parameters determine energy barriers and characteristic times of membrane-involved phenomena. Since the development of molecular dynamics (MD), a variety of in silico methods have been proposed for the determination of elastic parameters of simulated lipid membranes. These MD methods allow for the consideration of details unattainable in experimental techniques and represent a distinct scientific field, which is rapidly developing. This work provides a review of these MD approaches with a focus on theoretical aspects. Two main challenges are identified: (i) the ambiguity in the transition from the continuum description of elastic theories to the discrete representation of MD simulations, and (ii) the determination of intrinsic elastic parameters of lipid mixtures, which is complicated due to the composition–curvature coupling effect.
Functionalized GO Membranes for Efficient Separation of Acid Gases from Natural Gas: A Computational Mechanistic Understanding
Authors: Liu Quan , Yang Zhonglian , Liu Gongping , Sun Longlong , Xu Rong , Zhong Jing
Published: November 2022

Membrane separation technology is applied in natural gas processing, while a high-performance membrane is highly in demand. This paper considers the bright future of functionalized graphene oxide (GO) membranes in acid gas removal from natural gas. By molecular simulations, the adsorption and diffusion behaviors of several unary gases (N2, CH4, CO2, H2S, and SO2) are explored in the 1,4-phenylenediamine-2-sulfonate (PDASA)-doped GO channels. Molecular insights show that the multilayer adsorption of acid gases evaluates well by the Redlich-Peterson model. A tiny amount of PDASA promotes the solubility coefficient of CO2 and H2S, respectively, up to 4.5 and 5.3 mmol·g−1·kPa−1, nearly 2.5 times higher than those of a pure GO membrane, which is due to the improved binding affinity, great isosteric heat, and hydrogen bonds, while N2 and CH4 only show single-layer adsorption with solubility coefficients lower than 0.002 mmol·g−1·kPa−1, and their weak adsorption is insusceptible to PDASA. Although acid gas diffusivity in GO channels is inhibited below 20 × 10−6 cm2·s−1 by PDASA, the solubility coefficient of acid gases is certainly high enough to ensure their separation efficiency. As a result, the permeabilities (P) of acid gases and their selectivities (α) over CH4 are simultaneously improved (PCO2 = 7265.5 Barrer, αCO2/CH4 = 95.7; P(H2S+CO2) = 42075.1 Barrer, αH2S/CH4 = 243.8), which outperforms most of the ever-reported membranes. This theoretical study gives a mechanistic understanding of acid gas separation and provides a unique design strategy to develop high-performance GO membranes toward efficient natural gas processing.
A Novel Membrane-like 2D A’-MoS2 as Anode for Lithium- and Sodium-Ion Batteries
Authors: Sukhanova Ekaterina V. , Bereznikova Liudmila A. , Manakhov Anton M. , Al Qahtani Hassan S. , Popov Zakhar I.
Published: November 2022

Currently, new nanomaterials for high-capacity lithium-ion batteries (LIBs) and sodium- ion batteries (SIBs) are urgently needed. Materials combining porous structure (such as representatives of metal–organic frameworks) and the ability to operate both with lithium and sodium (such as transition-metal dichalcogenides) are of particular interest. Our work reports the computational modelling of a new A’-MoS2 structure and its application in LIBs and SIBs. The A’-MoS2 monolayer was dynamically stable and exhibited semiconducting properties with an indirect band gap of 0.74 eV. A large surface area, together with the presence of pores resulted in a high capacity of the A’-MoS2 equal to ~391 mAg−1 at maximum filling for both Li and Na atoms. High adsorption energies and small values of diffusion barriers indicate that the A’-MoS2 is promising in the application of anode material in LIBs and SIBs.
Microstructure and Hydrogen Permeability of Nb-Ni-Ti-Zr-Co High Entropy Alloys
Authors: Kashkarov Egor , Krotkevich Dmitriy , Koptsev Maxim , Ognev Sergei , Svyatkin Leonid , Travitzky Nahum , Lider Andrey
Published: November 2022

Hydrogen separation membranes are one of the most promising technologies for hydrogen purification. The development of high-entropy alloys (HEAs) for hydrogen separation membranes is driven by a “cocktail effect” of elements with different hydrogen affinities to prevent hydride formation and retain high permeability due to the single-phase BCC structure. In this paper, equimolar and non-equimolar Nb-Ni-Ti-Zr-Co high entropy alloys were fabricated by arc melting. The microstructure and phase composition of the alloys were analyzed by scanning electron microscopy and X-ray diffraction, respectively. The hydrogen permeation experiments were performed at 300–500 °C and a hydrogen pressure of 4 bar. In order to estimate the effect of composition and lattice structure on hydrogen location and diffusivity in Nb-Ni-Ti-Zr-Co alloy, ab initio calculations of hydrogen binding energy were performed using virtual crystal approximation. It was found that Nb-enriched and near equimolar BCC phases were formed in Nb20Ni20Ti20Zr20Co20 HEA while Nb-enriched BCC and B2-Ni(Ti, Zr) were formed in Nb40Ni25Ti18Zr12Co5 alloy. Hydrogen permeability tests showed that Nb20Ni20Ti20Zr20Co20 HEA shows lower activation energy and higher permeability at lower temperatures as well as higher resistance to hydrogen embrittlement compared to Nb40Ni25Ti18Zr12Co5 alloy. The effect of composition, microstructure and hydrogen binding energies on permeability of the fabricated alloys was discussed.
Residual Stress Properties of the Welded Thick Underwater Spherical Pressure Hull Based on Finite Element Analysis
Authors: Wang Fang , Kong Pinpin , Sun Zhongzhou , Zhang Jinfei , Chen Fengluo , Wu Yu , Wang Yongmei
Published: November 2022

Residual stress inevitably occurs at the weld in the process of manufacturing thick pressure hulls for manned submersibles, which affects the bearing capacity of the hull. In this study, an electron-beam-welded 32 mm-thick Ti-6Al-4V plate specimen is first tested, then the measured data of residual stress distribution is applied to validate the accuracy of the simulation method. Accordingly, three-dimensional numerical analysis on the equator welding by electron beam method of a 32 mm-thick Ti-6Al-4V spherical pressure hull is conducted to obtain the variation tendency of residual stress during the welding process. The results indicate that both compressive and tensile stresses exist along the weld path on the outer surface of the hull comparing to total tensile stresses on the inner surface. The maximum tensile stress that occurs on the inner surface approximates to 850 MPa, which is almost equivalent to the yield stress of the material. Based on the acceptance criterion that the peak value of residual stress due to weld technique is restricted to be less than 40% of the material yield strength in room temperature, post-weld heat treatment must be performed. Simulation on post-weld heat treatment for optimizing process parameters can be done by taking the results of welding simulation in the present study as input.
YOLOv4-Tiny-Based Coal Gangue Image Recognition and FPGA Implementation
Authors: Xu Shanyong , Zhou Yujie , Huang Yourui , Han Tao
Published: November 2022

Nowadays, most of the deep learning coal gangue identification methods need to be performed on high-performance CPU or GPU hardware devices, which are inconvenient to use in complex underground coal mine environments due to their high power consumption, huge size, and significant heat generation. Aiming to resolve these problems, this paper proposes a coal gangue identification method based on YOLOv4-tiny and deploys it on the low-power hardware platform FPGA. First, the YOLOv4-tiny model is well trained on the computer platform, and the computation of the model is reduced through the 16-bit fixed-point quantization and the integration of a BN layer and convolution layer. Second, convolution and pooling IP kernels are designed on the FPGA platform to accelerate the computation of convolution and pooling, in which three optimization methods, including input and output channel parallelism, pipeline, and ping-pong operation, are used. Finally, the FPGA hardware system design of the whole algorithm is completed. The experimental results of the self-made coal gangue data set indicate that the precision of the algorithm proposed in this paper for coal gangue recognition on the FPGA platform are slightly lower than those of CPU and GPU, and the mAP value is 96.56%; the recognition speed of each image is 0.376 s, which is between those of CPU and GPU; the hardware power consumption of the FPGA platform is only 2.86 W; and the energy efficiency ratio is 10.42 and 3.47 times that of CPU and GPU, respectively.
Analysis of Sequential Micromixing Driven by Sinusoidally Shaped Induced-Charge Electroosmotic Flow
Authors: Sun Haizhen , Li Ziyi , Wu Yongji , Fan Xinjian , Zhu Minglu , Chen Tao , Sun Lining
Published: November 2022

Multi-fluid micromixing, which has rarely been explored, typically represents a highly sought-after technique in on-chip biochemical and biomedical assays. Herein, we propose a novel micromixing approach utilizing induced-charge electroosmosis (ICEO) to implement multicomplex mixing between parallel streams. The variations of ICEO microvortices above a sinusoidally shaped floating electrode (SSFE) are first investigated to better understand the microvortex development and the resultant mixing process within a confined channel. On this basis, a mathematical model of the vortex index is newly developed to predict the mixing degree along the microchannel. The negative exponential distribution obtained between the vortex index and mixing index demonstrates an efficient model to describe the mixing performance without solving the coupled diffusion and momentum equations. Specifically, sufficient mixing with a mixing index higher than 0.9 can be achieved when the vortex index exceeds 51, and the mixing efficiency reaches a plateau at an AC frequency close to 100 Hz. Further, a rectangle floating electrode (RFE) is deposited before SSFE to enhance the controlled sequence for three-fluid mixing. One side fluid can fully mix with the middle fluid with a mixing index of 0.623 above RFE in the first mixing stage and achieve entire-channel mixing with a mixing index of 0.983 above SSFE in the second mixing stage, thereby enabling on-demand sequential mixing. As a proof of concept, this work can provide a robust alternative technique for multi-objective issues and structural design related to mixers.
Formation Techniques Used in Shape-Forming Microrobotic Systems with Multiple Microrobots: A Review
Authors: Konara Menaka , Mudugamuwa Amith , Dodampegama Shanuka , Roshan Uditha , Amarasinghe Ranjith , Dao Dzung Viet
Published: November 2022

Multiple robots are used in robotic applications to achieve tasks that are impossible to perform as individual robotic modules. At the microscale/nanoscale, controlling multiple robots is difficult due to the limitations of fabrication technologies and the availability of on-board controllers. This highlights the requirement of different approaches compared to macro systems for a group of microrobotic systems. Current microrobotic systems have the capability to form different configurations, either as a collectively actuated swarm or a selectively actuated group of agents. Magnetic, acoustic, electric, optical, and hybrid methods are reviewed under collective formation methods, and surface anchoring, heterogeneous design, and non-uniform control input are significant in the selective formation of microrobotic systems. In addition, actuation principles play an important role in designing microrobotic systems with multiple microrobots, and the various control systems are also reviewed because they affect the development of such systems at the microscale. Reconfigurability, self-adaptable motion, and enhanced imaging due to the aggregation of modules have shown potential applications specifically in the biomedical sector. This review presents the current state of shape formation using microrobots with regard to forming techniques, actuation principles, and control systems. Finally, the future developments of these systems are presented.
A Multi-Point Contact Model Considering Rough Surface for Linear Ultrasonic Motors: Validation and Simulation
Authors: He Ying , Yao Zhiyuan , Xu Hao
Published: November 2022

The performance and wear life of linear ultrasonic motors are directly determined by the stator–mover frictional contact behaviors. A complete contact model is important to clearly understand the stator–mover contact mechanism and accurately estimate the motor performance. In this paper, a multi-point frictional contact model considering the roughness of contact interfaces is presented based on a finite model of the stator and an analytical model of the mover. The static/dynamic contact behaviors and output performance of the motor can be simulated efficiently. A quantitative measuring methodology for the dynamic contact forces between the stator and mover is developed. The effectiveness of the contact model for simulating the stator–mover contact forces is first evaluated by experiment. Based on the developed model, several dynamic characteristics of a linear ultrasonic motor are discussed: (a) the static force transferred between contact interfaces under pre-pressure; (b) the transient forces and energy exchange between contact interfaces; (c) the steady-state output performance of motor under different electric excitation parameters; (d) the effects of micro-topography parameters on the output performance of the motor and the force transmission of the contact interface.
Hierarchical Activated Carbon–MnO2 Composite for Wide Potential Window Asymmetric Supercapacitor Devices in Organic Electrolyte
Authors: Diantoro Markus , Istiqomah Istiqomah , Fath Yusril Al , Mufti Nandang , Nasikhudin Nasikhudin , Meevasana Worawat , Alias Yatimah Binti
Published: November 2022

The consumption of electrical energy grows alongside the development of global industry. Generating energy storage has become the primary focus of current research, examining supercapacitors with high power density. The primary raw material used in supercapacitor electrodes is activated carbon (AC). To improve the performance of activated carbon, we used manganese dioxide (MnO2), which has a theoretical capacitance of up to 1370 Fg−1. The composite-based activated carbon with a different mass of 0–20% MnO2 was successfully introduced as the positive electrode. The asymmetric cell supercapacitors based on activated carbon as the anode delivered an excellent gravimetric capacitance, energy density, and power density of 84.28 Fg−1, 14.88 Wh.kg−1, and 96.68 W.kg−1, respectively, at 1 M Et4NBF4, maintaining 88.88% after 1000 test cycles.
Magnetic Interconnects Based on Composite Multiferroics
Authors: Khitun Alexander
Published: November 2022

The development of magnetic logic devices dictates a need for a novel type of interconnect for magnetic signal transmission. Fast signal damping is one of the problems which drastically differs from conventional electric technology. Here, we describe a magnetic interconnect based on a composite multiferroic comprising piezoelectric and magnetostrictive materials. Internal signal amplification is the main reason for using multiferroic material, where a portion of energy can be transferred from electric to magnetic domains via stress-mediated coupling. The utilization of composite multiferroics consisting of piezoelectric and magnetostrictive materials offers flexibility for the separate adjustment of electric and magnetic characteristics. The structure of the proposed interconnect resembles a parallel plate capacitor filled with a piezoelectric, where one of the plates comprises a magnetoelastic material. An electric field applied across the plates of the capacitor produces stress, which, in turn, affects the magnetic properties of the magnetostrictive material. The charging of the capacitor from one edge results in the charge diffusion accompanied by the magnetization change in the magnetostrictive layer. This enables the amplitude of the magnetic signal to remain constant during the propagation. The operation of the proposed interconnects is illustrated by numerical modeling. The model is based on the Landau–Lifshitz–Gilbert equation with the electric field-dependent anisotropy term included. A variety of magnetic logic devices and architectures can benefit from the proposed interconnects, as they provide reliable and low-energy-consuming data transmission. According to the estimates, the group velocity of magnetic signals may be up to 105 m/s with energy dissipation less than 10−18 J per bit per 100 nm. The physical limits and practical challenges of the proposed approach are also discussed.
Engineering Atomic-to-Nano Scale Structural Homogeneity towards High Corrosion Resistance of Amorphous Magnesium-Based Alloys
Authors: Qin Yuan , Zhang Wentao , Li Kanghua , Fu Shu , Lou Yu , Liu Sinan , Ge Jiacheng , Ying Huiqiang , Liu Wei-Di , Zuo Xiaobing , Shen Jun , Wei Shao-Chong , Hahn Horst , Ren Yang , Wu Zhenduo , Wang Xun-Li , Zhu He , Lan Si
Published: November 2022

Magnesium-based amorphous alloys have aroused broad interest in being applied in marine use due to their merits of lightweight and high strength. Yet, the poor corrosion resistance to chloride-containing seawater has hindered their practical applications. Herein, we propose a new strategy to improve the chloride corrosion resistance of amorphous Mg65Cu15Ag10Gd10 alloys by engineering atomic-to-nano scale structural homogeneity, which is implemented by heating the material to the critical temperature of the liquid–liquid transition. By using various electrochemical, microscopic, and spectroscopic characterization methods, we reveal that the liquid–liquid transition can rearrange the local structural units in the amorphous structure, slightly decreasing the alloy structure’s homogeneity, accelerate the formation of protective passivation film, and, therefore, increase the corrosion resistance. Our study has demonstrated the strong coupling between an amorphous structure and corrosion behavior, which is available for optimizing corrosion-resistant alloys.
Black Quartz from the Burano Formation (Val Secchia, Italy): An Unusual Gem
Authors: Caucia Franca , Scacchetti Maurizio , Marinoni Luigi , Gilio Mattia
Published: November 2022

The Burano Formation in Val Secchia in the province of Reggio Emilia is rich in black or very dark quartz. The crystals are often pitted by scars, rarely shiny, often opaque, rarely translucent, and about 3 cm long. However, they have a beautiful color and are generally euhedral and bi-terminate with simple habitus and well developed faces—for these characteristics, they are very sought after by collectors. Micro-Raman analyses showed the quartz contains abundant inclusions of anhydrite and graphite. The inclusions of anhydrite are responsible for the chromatic inhomogeneity, while the black color is linked to the presence of disordered graphite inclusions. LA-ICP-MS analyses did not show a significant presence of chromophore elements. Black quartz formed in the original evaporite deposits of gypsum, which, due to diagenesis and the increase in temperature during deep tectonic burial conditions, lost water of crystallization and subsequently transformed into anhydrite. After the formation of quartz crystals, the Burano Formation was exhumated and rehydrated, resulting in gypsification at conditions close to the surface. The black quartzes of the Burano Formation represent an appreciable gemological material for the development of local craftsmanship, even if the difficulties in reaching the deposit limit their marketing.
Recent Research Agendas in Mining Equipment Management: A Review
Authors: Liu Shi Qiang , Lin Zhaoyun , Li Debiao , Li Xiangong , Kozan Erhan , Masoud Mahmoud
Published: November 2022

Nowadays, with the advancement of technological innovations and wide implementation of modern mining equipment, research topics on mining equipment management are attracting more and more attention from both academic scholars and industrial practitioners. With this background, this paper comprehensively reviews recent publications in the field of mining equipment management. By analysing the characteristics of open-pit mine production and haulage equipment types, problem definitions, formulation models and solution approaches in the relevant literature, the reviewed papers are classified into three main categories, i.e., shovel–truck (ST); in-pit crushing–conveying (IPCC); and hybrid IPCC-ST systems. Research progress and characteristics in each categorized mining equipment system are discussed and evaluated, respectively. With a thorough assessment of recent research agendas, the significance of developing state-of-the-art mining equipment scheduling/timetabling methodologies is indicated, based on the application of classical continuous-time machine scheduling theory. Promising future research directions and hotspots are also provided for researchers and practitioners in the mining industry.
Comprehensive Metabolite Profiling of Four Different Beans Fermented by Aspergillus oryzae
Authors: Lee Yeon Hee , Lee Na-Rae , Lee Choong Hwan
Published: November 2022

Fermented bean products are used worldwide; most of the products are made using only a few kinds of beans. However, the metabolite changes and contents in the beans generally used during fermentation are unrevealed. Therefore, we selected four different beans (soybean, Glycine max, GM; wild soybean, Glycine soja, GS; common bean, Phaseolus vulgaris, PV; and hyacinth bean, Lablab purpureus, LP) that are the most widely consumed and fermented with Aspergillus oryzae. Then, metabolome and multivariate statistical analysis were performed to figure out metabolite changes during fermentation. In the four beans, carbohydrates were decreased, but amino acids and fatty acids were increased in the four beans as they fermented. The relative amounts of amino acids were relatively abundant in fermented PV and LP as compared to other beans. In contrast, isoflavone aglycones (e.g., daidzein, glycitein, and genistein) and DDMP-conjugated soyasaponins (e.g., soyasaponins βa and γg) were increased in GM and GS during fermentation. Notably, these metabolite changes were more significant in GS than GM. In addition, the increase of antioxidant activity in fermented GS was significant compared to other beans. We expect our research provides a basis to extend choice for bean fermentation for consumers and food producers.
Biological Assessment of the NO-Dependent Endothelial Function
Authors: Boughaleb Hasnae , Lobysheva Irina , Dei Zotti Flavia , Balligand Jean-Luc , Montiel Virginie
Published: November 2022

Nitric oxide (NO) is implicated in numerous physiological processes, including vascular homeostasis. Reduced NO bioavailability is a hallmark of endothelial dysfunction, a prequel to many cardiovascular diseases. Biomarkers of an early NO-dependent endothelial dysfunction obtained from routine venous blood sampling would be of great interest but are currently lacking. The direct measurement of circulating NO remains a challenge due by its high reactivity and short half-life. The current techniques measure stable products from the NO signaling pathway or metabolic end products of NO that do not accurately represent its bioavailability and, therefore, endothelial function per se. In this review, we will concentrate on an original technique of low temperature electron paramagnetic resonance spectroscopy capable to directly measure the 5-α-coordinated heme nitrosyl-hemoglobin in the T (tense) state (5-α-nitrosyl-hemoglobin or HbNO) obtained from fresh venous human erythrocytes. In humans, HbNO reflects the bioavailability of NO formed in the vasculature from vascular endothelial NOS or exogenous NO donors with minor contribution from erythrocyte NOS. The HbNO signal is directly correlated with the vascular endothelial function and inversely correlated with vascular oxidative stress. Pilot studies support the validity of HbNO measurements both for the detection of endothelial dysfunction in asymptomatic subjects and for the monitoring of such dysfunction in patients with known cardiovascular disease. The impact of therapies or the severity of diseases such as COVID-19 infection involving the endothelium could also be monitored and their incumbent risk of complications better predicted through serial measurements of HbNO.
Antioxidant Properties of Hemp Proteins: From Functional Food to Phytotherapy and Beyond
Authors: Zhang Jiejia , Griffin Jason , Li Yonghui , Wang Donghai , Wang Weiqun
Published: November 2022

As one of the oldest plants cultivated by humans, hemp used to be banned in the United States but returned as a legal crop in 2018. Since then, the United States has become the leading hemp producer in the world. Currently, hemp attracts increasing attention from consumers and scientists as hemp products provide a wide spectrum of potential functions. Particularly, bioactive peptides derived from hemp proteins have been proven to be strong antioxidants, which is an extremely hot research topic in recent years. However, some controversial disputes and unknown issues are still underway to be explored and verified in the aspects of technique, methodology, characteristic, mechanism, application, caution, etc. Therefore, this review focusing on the antioxidant properties of hemp proteins is necessary to discuss the multiple critical issues, including in vitro structure-modifying techniques and antioxidant assays, structure-activity relationships of antioxidant peptides, pre-clinical studies on hemp proteins and pathogenesis-related molecular mechanisms, usage and potential hazard, and novel advanced techniques involving bioinformatics methodology (QSAR, PPI, GO, KEGG), proteomic analysis, and genomics analysis, etc. Taken together, the antioxidant potential of hemp proteins may provide both functional food benefits and phytotherapy efficacy to human health.
Nitrogen-Doped Titanium Dioxide as a Hole Transport Layer for High-Efficiency Formamidinium Perovskite Solar Cells
Authors: Pochont Nitin Ralph , Sekhar Yendaluru Raja , Vasu Kuraganti , Jose Rajan
Published: November 2022

Perovskite solar cells (PSCs) offer advantages over widely deployed silicon solar cells in terms of ease of fabrication; however, the device is still under rigorous materials optimization for cell performance, stability, and cost. In this work, we explore a version of a PSC by replacing the polymeric hole transport layer (HTL) such as Spiro-OMeTAD, P3HT, and PEDOT: PSS with a more air-stable metal oxide, viz., nitrogen-doped titanium dioxide (TiO2:N). Numerical simulations on formamidinium (FA)-based PSCs in the FTO/TiO2/FAPbI3/Ag configuration have been carried out to depict the behaviour of the HTL as well as the effect of absorber layer thickness (∆t) on photovoltaic parameters. The results show that the cell output increases when the HTL bandgap increases from 2.5 to 3.0 eV. By optimizing the absorber layer thickness and the gradient in defect density (Nt), the device structure considered here can deliver a maximum power conversion efficiency of ~21.38% for a lower HTL bandgap (~2.5 eV) and ~26.99% for a higher HTL bandgap of ~3.0 eV. The results are validated by reproducing the performance of PSCs employing commonly used polymeric HTLs, viz. Spiro-OMeTAD, P3HT, and PEDOT: PSS as well as high power conversion efficiency in the highly crystalline perovskite layer. Therefore, the present study provides high-performing, cost-effective PSCs using TiO2:N.