bluuebunny/crossref_metadata_2025 huggingface dataset:
Transtorno alimentar, percepção da imagem corporal e estado nutricional em estudantes de uma instituição no interior da Paraíba
Authors: Morais Marcos Garcia Costa , Menezes Micaela de Sousa , Morais Tâmara Larryanne Costa , Santos Priscila Antão dos , Conceição Beatriz Souza de , Silva Edivania Mayara Mizael da , Costa Maysla Rayssa Silva , Lima Taisa Paiva de
Published: February 2023

O sexo feminino de maneira geral é muito suscetível à aceitação das pressões sociais, torna-se comum observar mulheres tendo alterações psiquiátricas e alimentares os transtornos alimentares são caracterizados como um distúrbio psiquiátrico, por apresentar alterações graves na conduta alimentar e muitas vezes estão associadas com a distorção de imagem corporal. O objetivo deste estudo foi analisar as relações entre imagem corporal e estado nutricional, e avaliar a prevalência de distúrbios emocionais, em estudantes. Trata-se de um estudo do tipo transversal, descritivo com abordagem quantitativa. A pesquisa foi realizada entre os meses de setembro a novembro de 2019, com estudantes, do sexo feminino, na faixa etária de 18 a 59 anos, que estavam regularmente matriculadas em instituição privada de ensino superior na cidade de Campina Grande-PB. Os dados foram coletados por meio de um questionário contendo desde a identificação do paciente, com informações pessoais, sociais, emocionais, demográficas e estilo de vida; Questionário de Autopercepção de Imagem; Escala de compulsão alimentar periódico (ECAP) e Patient Health Questionnaire-9 (PHQ-9). Além disso, foi realizada avaliação nutricional, para obtenção de Índice de Massa Corporal (IMC) e Circunferência da Cintura (CC). A partir dos resultados da presente pesquisa conclui-se que mesmo tendo sido considerado eutrófico na sua totalidade, o grupo estudado refere uma imagem corporal incompatível com a realidade, apresentando elevado índice de distorção da imagem corporal atual. Por fim, este estudo chama atenção para a parcela de estudantes jovens apresentando depressão e insatisfação com a imagem corporal.
Educação alimentar e nutricional como uma prática na escola: A visão do professor
Authors: Lorenzi Hayde Raquel , Del Pino José Claúdio , Oliveira Luciana Dias de
Published: February 2023

O presente artigo é oriundo de uma pesquisa de mestrado, para a qual foi realizado o método de um grupo focal aplicado a professoras de uma instituição privada do município de Porto Alegre. O trabalho teve como objetivo geral investigar o conhe-cimento e a adesão às práticas de Educação Alimentar e Nutricional (EAN) no ambiente escolar privado. Para dar sustenta-ção ao estudo, utilizou-se um referencial teórico baseado principalmente na legislação brasileira e em autores da área da edu-cação. Os resultados do grupo focal foram analisados em três eixos de discussão: eixo 1: a referência do adulto como exem-plo para a formação do sujeito; eixo 2: a importância da formação docente para estabelecer a EAN no ambiente escolar; eixo 3: a importância da EAN no ambiente escolar. A partir da análise realizada, aponta-se a importância da formação ade-quada para os profissionais da educação e do estabelecimento da EAN de maneira organizada no currículo escolar com es-tratégias que incluam tais saberes como parte da cultura escolar, buscando atingir toda a comunidade como um todo.
Possíveis mecanismos fisiopatológicos da disgeusia associada à infecção por SARS-CoV-2 – Revisão de literatura
Authors: Bueno Marcus Vinícius , Galvão Gustavo Souza , Neves Itamara Lucia Itagiba , Schröter Gabriella Torres , Moreira Maria Stella , Santos-Paul Marcela Alves dos , Carvalho Cíntia Maria Alencar de , Neves Ricardo Simões , Montano Tânia Cristina Pedroso
Published: February 2023

Desde o início da pandemia da COVID-19, em dezembro de 2019, muitos pacientes infectados relataram alterações de paladar e olfato como primeiros sintomas. O cirurgião-dentista deve estar capacitado para diagnosticar esta sintomatologia e encaminhar o paciente para serviços de saúde especializados. O presente estudo se propôs a realizar uma revisão narrativa sobre a possível patogênese da disgeusia e ageusia em pacientes infectados pelo SARS-CoV-2. Os dados foram coletados a partir de estudos identificados nos bancos de dados BVS, Google Acadêmico, LILACS, PubMed, SciELO e Web of Science, utilizando-se como descritores: disgeusia, ageusia, fisiopatologia e coronavírus. Dentre os possíveis mecanismos para a disgeusia, destacam-se a invasão viral em tecido nervoso, acometimento secundário às alterações de olfato, relação com comorbidades e medicamentos, associação à grande presença do vírus na saliva e sua alta afinidade pelos diversos receptores da enzima conversora de angiotensina-2 presentes na cavidade bucal. Portanto, alterações de paladar são sintomas típicos em pacientes infectados pelo SARS-CoV-2 e que tendem a regredir com o tempo. Entretanto, sua fisiopatologia, mecanismo de ação e prognóstico ainda não são bem estabelecidos, exigindo mais estudos experimentais.
Molecular detection and genotype analysis of Kudoa septempunctata from food poisoning outbreaks in Korea
Authors: Sung Gyung-Hye , Park In-Ji , Koo Hee-Soo , Park Eun-Hee , Lee Mi-Ok
Published: February 2023

Concerns about foodborne illnesses caused by Kudoa septempunctata are steadily growing, but reports of K. septempunctata in clinical and food specimens related to food poisoning in Korea are limited. This study aimed to genetically identify K. septempunctata in patients with acute diarrhea and in clinical and food samples related to food poisoning caused by sashimi consumption. Both real-time and nested polymerase chain reaction assays were performed to detect K. septempunctata 18S and 28S rDNA genes in the stools of 348 patients with acute diarrhea, 11 samples (6 stool and 5 rectal swab samples) from patients with food poisoning, and 2 raw Paralichthys olivaceus samples collected from a restaurant where a food poisoning incident occurred. K. septempunctata was identified in 5 clinical specimens (4 stools and 1 rectal swab) and 1 P. olivaceus sashimi sample. All detected K. septempunctata were of genotype ST3. This is the first study to identify K. septempunctata in both patients and food samples with epidemiological relevance in Korea, providing evidence that it is a pathogen that causes food poisoning. Also, this is the first study to confirm the presence of K. septempunctata genes in rectal swabs. Despite continuing suspected occurrences of Kudoa foodborne outbreaks, the rate of identification of K. septempunctata is very low. One reason for this is the limitation in obtaining stool and vomit samples for the diagnosis of Kudoa infection. We strongly suggest the inclusion of rectal swabs among the diagnostic specimens for Kudoa food poisoning.
Antimalarial effect of synthetic endoperoxide on synchronized Plasmodium chabaudi infected mice
Authors: Aly Nagwa S. M. , Matsumori Hiroaki , Dinh Thi Quyen , Sato Akira , Miyoshi Shin-Ichi , Chang Kyung-Soo , Yu Hak Sun , Kobayashi Fumie , Kim Hye-Sook
Published: February 2023

The discovery of new antimalarial drugs can be developed using asynchronized Plasmodium berghei malaria parasites in vivo in mice. Studies on a particular stage are also required to assess the effectiveness and mode of action of drugs. In this report, we used endoperoxide 6-(1,2,6,7-tetraoxaspiro [7.11] nonadec-4-yl) hexan-1-ol (N-251) as a model antimalarial compound on P. chabaudi parasites. We examined the antimalarial effect of N-251 against ring-stage- and trophozoite-stage-rich P. chabaudi parasites and asynchronized P. berghei parasites using the 4-day suppressive test. The ED50 values were 27, 22, and 22 mg/kg, respectively, and the antimalarial activity of N-251 was verified in both rodent malaria parasites. To assess the stage-specific effect of N-251 in vivo, we evaluated the change of parasitemia and distribution of parasite stages using ring-stage- and trophozoite-stage-rich P. chabaudi parasites with one-day drug administration for one life cycle. We discovered that the parasitemias decreased after 13 and 9 hours post-treatment in the ring-stage- and trophozoite-stage-rich groups, respectively. Additionally, in the ring-stage-rich N-251 treated group, the ring-stage parasites hindered trophozoite parasite development. For the trophozoite-stage-rich N-251 treated group, the distribution of the trophozoite stage was maintained without a change in parasitemia until 9 hours. Because of these findings, it can be concluded that N-251 suppressed the trophozoite stage but not the ring stage. We report for the first time that N-251 specifically suppresses the trophozoite stage using P. chabaudi in mice. The results show that P. chabaudi is a reliable model for the characterization of stage-specific antimalarial effects.
DETEKSI PILIHAN JAWABAN OTOMATIS PADA LEMBAR JAWABAN KOMPUTER MENGGUNAKAN METODE IMAGE THRESHOLDING DAN CONTOUR SORTING
Authors: Oktagalu Pratamasunu Gulpi Qorik , Pawening Ratri Enggar , Wulandari Uky Novita
Published: February 2023

Penggunaan lembar jawaban komputer mengalami peningkatan di berbagai instansi seperti halnya pendidikan sedangkan informasi dalam lembar jawaban komputer harus terekam secara sempurna. Pihak sekolah harus memiliki alat scanner tertentu dengan harga yang mahal untuk mendeteksi pilihan jawaban. Padahal saat ini banyak alternatif lain untuk memindai bisa menggunakan scanner biasa yang harganya jauh lebih murah atau menggunakan aplikasi android yang dapat mengambil foto dengan kamera dan merubahnya menjadi menyerupai hasil scan, tetapi baik scanner biasa atau pun aplikasi android tersebut tidak dapat langsung mendeteksi pilihan jawaban secara otomatis. Dari permasalahan di atas, dibutuhkan suatu metode untuk mendeteksi pilihan jawaban dan mengevaluasi pilihan jawaban tersebut. Dengan penelitian ini diharapkan dapat mengembangkan suatu metode untuk mendeteksi pilihan jawaban pada lembar jawaban komputer secara otomatis sehingga akan mendapatkan hasil yang lebih akurat. Pada penelitian ini dikembangkan sebuah metode yang dapat mendeteksi pilihan jawaban secara otomatis dengan menggunakan metode image thresholding dan contour sorting. Maka dapat disimpulkan, bahwasanya 95% metode image thresholding dan contour sorting berhasil mendeteksi pilihan jawaban secara otomatis pada lembar jawaban komputer
DOMPET SANTRI DI PONDOK PESANTREN RIYADLUS SHOLIHIN BERBASIS MOBILE
Authors: Shudiq Wali Ja'far , Hasyim Fuadz , Najiburrahman Moh Faiz
Published: February 2023

Pesantren Riyadlus Sholihin adalah institusi pendidikan agama berbasiskan pondok maupun non-pondok yang mengatur segala hal yang berkaitan dengan penyelenggaraan pendidikan keagamaan dan keuangan santri. Pada saat ini proses penyimpanan data keuangan santri masih berupa lembaran kertas sehingga pada saat pencarian data santri atau berkas-berkas masih membutuhkan waktu yang lama, karena masih harus membuka dan mencari satu persatu domumen atau data-data yang ada juga seringnya terjadi kehilangan atau kesalahan penghitungan dari petugas.. Pada saat ini orang tua juga tidak bisa mengontrol rekapitulasi keuangan putranya sehingga masih harus bertanya kepada petugas setiap kali menyetor uangnya ke pondok juga terdapat masalah ketika uang putranya habis terkadang orang tua lupa untuk mengirim putranya. Penelitian ini menggunakan metode Waterfall atau metode yang dalam pengerjaannya berurutan atau prosedural. Adapun sumber data yang digunakan adalah data – data wawancara dan observasi.Berdasarkan analisa data yang dilakukan, bahwa telah dihasilkannya aplikasi dompet santri di Pondok Pesantren Riyadlus Sholihin berbasis mobile, sehingga proses sehingga proses pencatatan dan pelaporan keuangan kepada wali santri bisa terwujud. Kesimpulan dari penelitian ini adalah  aplikasi dompet santri yang dirancang dengan menggunakan bahasa pemrograman Android pada software Android Studio ini dapat memberikan informasi kepada wali santri mengenai keuangan putranya. Berdasarkan hasil pengujian dan perhitungan  disimpulkan bahwa persentase yang diperoleh berjumlah 80,62% yaitu adalah sangat baik.
Pengembangan Pembelajaran Game Edukasi Aritmatika Dasar untuk Anak Madrasah Ibtida’iah Nurul Mun’im PP. Nurul Jadid
Authors: Shudiq Wali Ja'far , Fila Nining , Khotimah Putri Dwi Chusnul
Published: February 2023

Perkembangan game saat ini kebanyakan hanya digunakan untuk kesenangan dan hiburan semata, kurang menekankan pada sisi edukasi. Pendidikan berhitung pada kalangan anak-anak sekolah dasar dirasa masih sangat kurang, apalagi game yang ada saat ini hanya merujuk kepada kekerasan inilah yang menyebabkan anak-anak mejadi kecanduan dalam bermain game dan akhirnya berujung menjadi malas dalam belajar. Aplikasi Game Edukasi Matematika Dengan Konsep Aritmatika Anak Berbasis Android ini bertujuan untuk Menghasilkan sebuah aplikasi game yang dapat melatih anak ataupun siswa untuk belajar berhitung dengan mudah dan menyenangkan sehingga anak tidak bosan dengan metode pembelajaran yang monoton. Diciptakannya dalam bentuk mobile bertujuan supaya mudah untuk dibawa kemana saja. Dengan diciptakannya game ini memungkinkan pengguna untuk belajar berhitung atau aritmatika lebih menyenangkan karena didukung dengan desain yang menarik. Hasil tersebut menunjukkan bahwa  game  edukasi android dapat digunakan sebagai fasilitas media pembelajaran pengenalan bilangan untuk siswa SD/MI
Implementasi Algoritma Convolutional Neural Networks (CNN) Untuk Klasifikasi Batik
Authors: Rizal Fathur , Hasyim Fuadz , Malik Kamil , Yudistira Yudistira
Published: February 2023

Batik adalah salah satu budaya khas Indonesia dan sudah diakui sebagai warisan budaya Internasional oleh UNESCO (The United Nations Educational, Scientific and Cultural Organization) pada tanggal 2 Oktober 2009. Batik telah menjadi warisan budaya turun temurun di seluruh Indonesia khususnya di daerah Jawa. Saat ini ada ratusan motif kain batik dari seluruh penjuru Indonesia. Banyaknya pola batik di Indonesia mengakibatkan sulitnya masyarakat mengidentifikasi motif pada batik.  penelitian ini dapat mempermudah pengenalan pola batik. Salah satu teknologi kecerdasan buatan dengan sebutan artiﬁcial intelligence (AI) adalah pembelajaran mesin dengan menggunakan metode computer vision Salah satu model pembelajaran mesin tersebut adalah jaringan syaraf tiruan (JST) dengan menggunakan banyak lapisan, sehingga dengan adanya model tersebut maka dapat lebih baik lagi performa komputasi dengan menggunakan teknik Deep Learning. Metode yang digunakan adalah Convolutional Neural Networks (CNN) dengan melakukan klasiﬁkasi gambar pada batik berbasis komputer dengan memanfaatkan kecerdasan buatan (artiﬁcial intelligence). Hasil dari penelitian yang telah dilakukan pada pengujian terhadap 200 dataset dan 20 label diperoleh nilai akurasi yang tertinggi adalah “Batik Megamendung dan Batik Celup” dengan nilai akurasi 80% dan 60%, hasil accuracy yang diperoleh dari proses pelatihan model dari 200 epoch yang tertinggi adalah 90%.
Pengembangan Aplikasi Pelaporan Absensi Siswa Via Whatsapp DI MI Raudlatul Ulum Karanggeger
Authors: Maulidiansyah Maulidiansyah
Published: February 2023

MI Raudlatul Ulum adalah sekolah tinggat dasar di desa Karanggeger Kec. Pajarakan Kab. Probolinggo. Untuk menjaga kedisiplinan siswa, MI Raudlatul Ulum ingin melakukan monitoring dan pelaporan rekap absensi siswa kepada wali murid. Hal ini berguna agar wali murid tahu kerajinan putra/putrinya disekolah. Dan untuk mempermudah pengiriman laporan absensi, pihak sekolah ingin menggunakan media Whatsapp. Hanya saja butuh waktu lama dan tidak mudah jika pelaporan dilakukan secara manual, mengingat jumlah siswa pada MI Raudlatul Ulum yang tidak sedikit. Maka dari itu, penelitian ini bertujuan untuk mengembangkan aplikasi yang bisa mengirim banyak pesan via WhatsApp secara otomatis. Dengan aplikasi ini diharapkan akan mempermudah dan mempercepat pihak sekolah dalam melakukan pengiriman laporan absensi siswa via WhatsApp. Metode pengumpulan data yang digunakan dalam penelitian ini adalah observasi dan wawancara kepada bagian tata usaha pada sekolah MI Raudlatul Ulum. Adapun output dari penelitian ini adalah aplikasi pengirim pesan otomatis via WhatsApp. Dan diharapkan aplikasi ini bisa membantu pihak sekolah dalam melakukan pelaporan absensi siswa
APLIKASI E-MAN (MANAJEMEN, ANALISIS DAN NAVIGASI) INVENTARIS DI SMK NEGERI 1 KOTAANYAR BERBASIS WEBSITE DENGAN CODEIGNITER 4
Authors: Hudaya Kharisman Kholid , Sya'roni Wahab
Published: February 2023

Pengelolaan data Inventaris pribadi SMK Negeri 1 Kotaanyar saat ini masih memiliki banyak permasalahan seperti pemanfaatan aset untuk kegiatan belajar mengajar tidak terpantau yang disebabkan data aset yang belum tersinkron dengan data pegawai dan sistem pencatatan yang dilakukan masih menggunakan pencatatan manual dan menginput data pada aplikasi Excel sehingga pihak-pihak pengurus aset sekolah mengalami kendala dalam meninjau langsung detail data aset yang dimiliki sekolah. Berdasarkan uraian tersebut maka perlu dibangun suatu sistem inventarisasi yang dapat mengatasi permasalahan yang ada dan memudahkan sekolah memanajemen, menganalisis dan memonitor inventaris dengan cepat saat dibutuhkan. Hasil dari penelitian ini yaitu Sistem Pengelolaan Inventaris di SMKN 1 Kotaanyar yang telah dibangun mempermudah pihak sekolah dalam melakukan proses Inventarisasi dan penyajian data yang cepat karena permasalahan seperti data aset yang tidak tersinkronisasi dan metode pencatatan sistem lama yang diterapkan sudah teratasi dengan adanya Aplikasi E-MAN yang berbasis website dengan Codeigniter 4.
Membangun Aplikasi Pengajuan Surat di Fakultas Teknik Universitas Nurul Jadid Berbasis Frontend Web
Authors: HAKIM LUKMAN , Arifin Zainal , Sya'roni Wahab
Published: February 2023

Pelayanan surat menyurat di Fakultas Teknik saat ini dilakukan secara langsung dengan pemohon datang ke fakultas teknik dan proses penerbitannya menggunakan Microsoft Word, dalam pengajuan surat yang dilakukan perubahan dalam satu file word dan masih belum memanfaatkan fitur Mail Merge yang ada di Microsoft Excel, sehingga apabila ada pengajuan surat lainnya akan menghilangkan histori surat sebelumnya, kondisi tersebut menyulitkan kepala tata usaha atau sekretaris Prodi tidak bisa memonitoring pengajuan surat oleh mahasiswa atau dosen. Tujuan penelitian ini adalah membangun sistem monitoring pengajuan surat berbasis web yang dapat diakses dimanapun dan kapanpun. Penelitian ini menggunakan metodologi R&D (Research and Development) dengan model pengembangan Scrum. Desain sistem yang digunakan dalam penelitian ini menggunakan prosedural yaitu flowchart, data flow diagram dan entity relationship diagram. Sistem berbasis web ini dapat membantu memudahkan kepala tata usaha dalam memonitoring pengajuan surat yang diajukan mahasiswa. Berdasarkan hasil penelitian yang dilakukan dengan menggunakan pengujian eksternal diperoleh nilai 78,3% yang dapat disimpulkan bahwa aplikasi tersebut dikategorikan layak untuk digunakan dalam monitoring pengajuan surat di Fakultas Teknik Universitas Nurul Jadid Paiton.
ANALISIS IMPLEMENTASI BUDAYA 5S DALAM PENATAAN LABORATORIUM TEKNIK INDUSTRI UNIVERSITAS HASYIM ASYâ€™ARI
Authors: Ardi Setiawan  , Sulung Rahmawan Wira Ghani
Published: February 2023

Industrial engineering is an engineering field that includes the knowledge of design, repair, and manufacture integrated systems consisting of people, raw materials, information, equipment, and energy. The laboratory is used to complete the observed research, especially industrial problems in the industrial engineering department. Based on previous research, as many as 62.5% of lecturers found it difficult to store laboratory equipment in the workspace and 81.25% suggested to rearrange the layout of the laboratory. This study aimed to design the layout of laboratory equipment by using the 5S method. The first step to do the research was reducing laboratory activities, initial identifying of laboratory layouts, grouping the machines and tools, designing the laboratory layouts, implementing 5S, and evaluating new designs by using the Self-Assessment Form. The resulting layout is in accordance with the 5S principle, the design of the wardrobe is relatively small, and the design adapts to the space and equipment stored. The results then showed that 5S performance data in the laboratory before the implementation was 0.71 which in the fair rating category, and after the application of 5S the average score becomes 1.5 which in the excellent rating category. However, it shows that there is two-fold increase before the implementation 5S method.
Overview of results from continuous GPS observations in Iceland from 1995 to 2010
Authors: Geirsson Halldór , Árnadóttir Thóra , Hreinsdóttir Sigrún , Decriem Judicael , LaFemina Peter C. , Jónsson Sigurjón , Bennett Richard A. , Metzger Sabrina , Holland Austin , Sturkell Erik , Villemin Thierry , Völksen Christof , Sigmundsson Freysteinn , Einarsson Páll , Roberts Matthew J. , Sveinbjörnsson Hjörleifur
Published: February 2023

Iceland is a natural laboratory for a variety of processes associated with crustal deformation, such as earthquakes, magmatic events, tectonic plate motions, and glacial load changes. Continuous GPS (CGPS) measurements started in Iceland in 1995, and since then data from the network have helped to shed light on many different active deformation processes. The number of CGPS sites in Iceland tripled during 2006–2008, as a result of an international collaborative effort coordinated by Icelandic scientists. By early 2010 the number of CGPS stations in Iceland had reached 64, located primarily around and within the North-American–Eurasian plate boundary zone. Since its initiation, the CGPS network has played an important role in monitoring volcanoes and seismogenic areas, most notably during the 2009–2010 Eyjafjallajökull volcano unrest. Plate spreading of up to 2 cm per year usually dominates the horizontal motion observed at the CGPS sites, while uplift is observed at many of the stations due to recent retreat of the Icelandic ice caps. Co-seismic and post-seismic deformation of the largest earthquakes in 2000 and 2008 in the South Iceland Seismic Zone were captured by the network, and high-rate (1 Hz) CGPS observations helped to identify two magnitude 6 mainshocks in 2008 that were separated in time by only 2–3 seconds. The CGPS network has thus enabled us to monitor deformation occurring over days to months caused by migration of magma or fluids, post-seismic transients, rapid deformation caused by earthquakes and eruptions, as well as the long term plate spreading signal.
The Kerlingar fault, Northeast Iceland: A Holocene normal fault east of the divergent plate boundary
Authors: Hjartardóttir Ásta Rut , Einarsson Páll , Brandsdóttir Bryndís
Published: February 2023

The Kerlingar fault is a ∼30 km long fault located at the boundary between the Northern Volcanic Rift Zone, and the Tertiary Eastern Fjords Block in Iceland. The fault has a throw of 2–9 m down to the east and is most likely a normal fault. It probably ruptured in several earthquakes over extended time, but assuming it ruptured in one event it would have a magnitude of about $M_w$ = 6.7. The Kerlingar fault forms a sharp offset in a flat moraine, showing that the fault was active in the Holocene. Several characteristics of the fault are different from that of the presently active fissure swarms of the NVZ. It is unusually long, straight and continuous, and it is parallel with the boundary between the NVZ and EFB not perpendicular to the plate spreading. We consider three possible explanations for the existence of the fault. It may be formed in a rifting event, by stress transfer in relation to the Húsavík transform, or by a stress field caused by rapid crustal unloading during the last deglaciation. We favour the third explanation but note that the other two cannot be excluded. Differential movements at the NVZ–EFB boundary during deglaciations can occur as the two crustal blocks have different density, Young’s modulus, thickness, and subcrustal viscosity. They therefore respond differently to the unloading. This may explain why the fault is parallel with the NVZ–EFB boundary and not with the Holocene fissure swarms in the NVZ. Other faults at the NVZ–EFB boundary may be formed in a similar manner. Magma may have intruded some of them to form the distinct arcuate pattern of hyaloclastite ridges at the boundary between the NVZ and the EFB. Future model calculations could constrain better the effects this process has on the formation of faults.
Geomorphic implications of the retreat of Breiðamerkurjökull in the southern part of the Skálabjörg ridge, Esjufjöll, Iceland
Authors: Dabski Maciej , Angiel Piotr
Published: February 2023

The Skálabjörg nunatak, one of the summits of the Esjufjöll central volcano (SE Iceland), has been glacially eroded by the Breiðamerkurjökull outlet glacier for thousands of years. Since the end of the Little Ice Age, six to eight lateral moraine ridges have formed on the slopes of Skálabjörg. Ice-dammed lakes have also developed in the southernmost part of Skálabjörg and in Fossadalur. The highest and largest moraine ridge is situated 85–98 m above the contemporary glacier margin. Dating based on lichenometry, cartographic and photographic documentation indicates that the initial exposure of the highest moraine ridge occurred between AD 1896 and 1930 along its eastern margin and between AD 1915 and 1930 along its southwestern margin, giving an average glacier surface lowering rate of 0.8–1.3 m/yr in the southern hills of Skálabjörg. Hills above the highest moraine ridge bear imprints of earlier glaciation, most notably glacially abraded rock outcrops and transported boulders. Small active solifluction tongues and lobes with stone-armoured fronts cover the surface above the LIA limit. Small-scale and large-scale stripes exhibiting sorting down to c. 15 cm are abundant. The uppermost parts of the Skálabjörg nunatak are heavily frost-weathered bedrock outcrops, and can be classified as a typical periglacial domain.
Improved precision of delay times determined through cross correlation achieved by out-member averaging
Authors: Menke William , Menke Hannah
Published: February 2023

The estimation of differential time delays between similar but noisy time series by cross-correlation is an important component of many data processing applications. In many cases, delays are determined for every pair of time series drawn from a large set of them. For instance, modern earthquake location techniques utilize the differential delays between all P waves (or S waves) observed at a common station, sets that could have thousands of members (one for each earthquake pair). We show that the variance of delay time estimates can be reduced by a factor of 2 to 4 through a process we term out-member averaging. It utilizes an estimate of the delay time constructed by adding together the delays between each member of the pair and a third time series. In addition to decreasing the variance of the estimates, thus potentially improving the accuracy of earthquake locations by a factor of 2–4, it also demonstrates that data from an earthquake can contribute to the location process, even when insufficient data are available to locate that particular earthquake.
Volume estimates of nine prehistoric (~1860 BC – 870 AD) Katla tephra layers
Authors: Óladóttir Bergrún Arna , Larsen Guðrún , Sigmarsson Olgeir
Published: February 2023

Activity of the Katla volcano, under the Mýrdalsjökull ice cap, is characterized by explosive basaltic eruptions and occasional silicic eruptions. Tephrochronology indicates that it has erupted over 300 times during the last ∼8400 years. About 40 soil sections, distributed around the volcano although the majority are located to the east and northeast, have been measured in order to map the thickness of nine selected prehistoric Katla tephra layers, younger than ∼1860 BC (Hekla-S tephra) but older than ∼870 AD (Settlement tephra, Bárðarbunga–Veiðivötn volcanic system). The volume of these layers was calculated from isopach maps, using the Surfer© Golden Software, and compared to published volume estimates of eight historical tephra layers (younger than ∼870 AD), all of which are ≤1 km³ of freshly fallen tephra. Maximum thickness values similar to those applied in the volume estimates of the historical tephra were used. The volume range of the prehistoric tephra layers on land is from 0.2–2.7 km³, with the more voluminous layers being significantly larger and more frequent than those produced by historical eruptions at Katla. The observed volume difference between the two time periods could be related to changes to the magma plumbing system under the Katla volcano.
ASSESSORIA/CONSULTORIA NA POLÍTICA NACIONAL DE ASSISTÊNCIA SOCIAL:
Authors: Barbosa Camila Castelari , Ávila Maria Auxiliadora , Moreira Alessandro Messias
Published: February 2023

Busca-se discutir a atuação de Assistentes Sociais no campo das assessorias e consultorias na Política Nacional de Assistência Social (PNAS), enquanto espaço de atuação profissional, se não recente, mas que ainda demanda estudos, pois a produção sobre o tema (embora pertinente e densa) ainda é restrita. Apresenta-se o desenvolvimento histórico da Política de Assistência Social, assim como os argumentos e também as preocupações dos principais autores que tratam do tema. Os argumentos refletem a importância da assessoria/consultoria para os profissionais do Serviço Social, embora sejam objeto de preocupação os riscos decorrentes de lacunas na formação inicial e continuada, relativos à atuação em consultorias e assessorias.
ENSINO HÍBRIDO NA GRADUAÇÃO
Authors: Quintairos Paulo
Published: February 2023

A pandemia da covid-19 impôs às instituições de ensino um longo período de ensino totalmente remoto. Nesse período, a continuidade das atividades didático-pedagógicas foi possível com a adoção de ferramentas digitais aliadas a métodos ativos de ensino. Após o período das aulas totalmente remotas, o retorno presencial trouxe à tona a necessidade de incorporar as melhores práticas e ferramentas ao processo regular de ensino aprendizagem. A busca pelo melhor modelo que incorpore essas práticas e ferramentas digitais ao modelo de ensino é uma tarefa árdua e que certamente levará a uma diversidade de modelos, adaptados as necessidades e peculiaridades dos cursos e das instituições. Neste artigo será apresentada uma proposta de projeto de adaptação e incorporação das ferramentas digitais para um curso superior presencial, sujeito ao teto máximo de atividades remotas estabelecido pelo MEC. O método de pesquisa será documental e baseado na experiência do autor em instituições de ensino superior. O resultado esperado é um projeto flexível de implementação das ferramentas digitais para cursos superiores, partindo-se do estágio de nenhuma carga horária remota e sem propor alterações da grade curricular ou da estrutura do curso. A implementação levará em conta as melhores práticas de gestão de projetos, sendo baseada no PMBOK.
O EMPREGO DA LOUSA DIGITAL NA EDUCAÇÃO INFANTIL PÚBLICA DO MUNICÍPIO DE ARGIRITA/MG - BRASIL
Authors: Zaiter Alessandra Rezende Caçador , Santos Priscila Costa , Santos André Felipe Costa
Published: February 2023

A presença e o uso frequente das Tecnologias Digitais da Informação e Comunicação (TDIC) na atualidade tem provocado transformações na sociedade, facilitando a troca de informações e conhecimento. E, para acompanhar esses caminhos inovadores, a educação necessita acompanhar tais mudanças. Nesse sentido, este artigo tem por objetivo apresentar as práticas pedagógicas inovadoras integradas ao uso da lousa digital na Educação Infantil, no contexto de uma escola pública do município de Argirita, Minas Gerais. A pesquisa segue uma abordagem qualitativa com a adoção do método Estudo de Caso. Para a análise dos dados, foram utilizadas entrevistas, observações e reflexões dos autores que nortearam o estudo. Como resultado, verificou-se que a integração da lousa digital nas práticas pedagógicas dos professores da Educação infantil é favorável como apoio e motivação para professores e alunos, contribuindo para a construção de novas formas de ensino e aprendizagem através das linguagens digitais.
Fossil Diatoms Reveal Natural and Anthropogenic History of Jackson Lake (Wyoming, USA)
Authors: Dilworth John , Stone Jeffery R. , Yeager Kevin M. , Thigpen J. Ryan , McGlue Michael M.
Published: February 2023

Jackson Lake supplies valuable cultural and provisioning ecosystem services to the Upper Snake River watershed in Wyoming and Idaho (western USA). Construction of Jackson Lake Dam in the early 20th century raised lake level by ∼12 m, generating an important water resource supporting agriculture and ranching, as well as tourism associated with Grand Teton National Park. Outlet engineering drastically altered Jackson Lake’s surface area, morphology, and relationship with the inflowing Snake River, yet the consequences for nutrient dynamics and algae in the lake are unknown. Here, we report the results of a retrospective environmental assessment completed for Jackson Lake using a paleolimnological approach. Paleoecological (diatoms) and geochemical datasets were developed on a well-dated sediment core and compared with available hydroclimate data from the region, to assess patterns of limnological change. The core spans the termination of the Little Ice Age and extends to the present day (∼1654–2019 CE). Diatom assemblages prior to dam installation are characterized by high relative abundances of plankton that thrive under low nutrient availability, most likely resulting from prolonged seasonal ice cover and perhaps a single, short episode of deep convective mixing. Following dam construction, diatom assemblages shifted to planktic species that favor more nutrient-rich waters. Elemental abundances of sedimentary nitrogen and phosphorous support the interpretation that dam installation resulted in a more mesotrophic state in Jackson Lake after ∼1916 CE. The data are consistent with enhanced nutrient loading associated with dam emplacement, which inundated deltaic wetlands and nearshore vegetation, and perhaps increased water residence times. The results of the study highlight the sensitivity of algal composition and productivity to changes in nutrient status that accompany outlet engineering of natural lakes by humans and have implications for water resource management.
Effects on rumen microbiome and milk quality of dairy cows fed a grass silage-based diet supplemented with the macroalga Asparagopsis taxiformis
Authors: Krizsan Sophie J. , Ramin Mohammad , Chagas Juana C. C. , Halmemies-Beauchet-Filleau Anni , Singh Abhijet , Schnürer Anna , Danielsson Rebecca
Published: February 2023

The objective was to determine the effects on rumen microbiome and milk quality of reducing the methane (CH4) produced from enteric fermentation by the addition of Asparagopsis taxiformis (AT) to the diets of dairy cows. Six Nordic Red cows at 122 ± 13.7 (mean ± SD) days in milk, of parity 2.7 ± 0.52 and producing 36 kg ± 2.5 kg milk per day at the start of the trial were divided into three blocks by milk yield and assigned to an extra-period Latin-square change-over design comprising two dietary treatments. An extra period of observation was added to the Latin-square change-over design to control for carry-over effects. The dietary treatments were a diet consisting of grass silage and a commercial concentrate mixture (60:40) either not supplemented or supplemented with 0.5% AT on an organic matter intake basis. On average, daily CH4 production, CH4 yield, and CH4 intensity decreased by 60%, 54%, and 58%, respectively, in cows fed the diet supplemented with AT. Furthermore, hydrogen gas emitted by cows fed diets supplemented with AT increased by more than five times compared with cows fed a non-AT-supplemented diet. Feed intake was decreased and milk production altered, reflecting a decreased yield of milk fat in cows fed an AT-supplemented diet, but feed efficiency increased. Rumen fermentation parameters were changed to promote propionate rather than acetate and butyrate fermentation. The most prominent change in milk quality was an increase in bromine and iodine when the diet was supplemented with AT. The reduction in CH4 was associated with a shift from Methanobrevibacter to Methanomethylophilaceae in the archaeal population and a lower relative abundance of Prevotella in the bacterial population. Changes in milk fat odd-numbered and branched-chain fatty acids in the current study of AT supplementation support observed differences in ruminal archaeal and bacterial populations.
Worldwide productivity and research trend of publications concerning electroactive materials and spinal cord injury: A bibliometric study
Authors: Liu Sirui , Song Lin , Dai Weishu , Liu Mengdie , Zhang Huijing , Zhang Xueyan , Li Hongyu , Liu Xiu , Lv Yan , Hu Ying
Published: February 2023

Purpose: We investigated the current state and trends in the area during the previous 10 years using bibliometric approaches to evaluate the global scientific output of research on electroactive materials and spinal cord injury.

Methods: Studies on spinal cord injury in electroactive materials that were published between 2012 and 2022 were located using the Web of science (WOS) datebase. The software programs bibliometrix R-package and CiteSpace were used to do quantitative analyses of annual publications, nation, author, institution, journal source, co-cited references, and keywords. The studies were categorized by the research’s main points using a qualitative analysis, and publications having more than 10 citations each year.

Results: In the final analysis, 1,330 relevant papers or reviews were included. There is an increased tendency in both the average annual citation rate and the number of publications in the discipline. The United States and the University of Toronto are the countries and institutions that have contributed the most to this discipline, respectively. The majority of authors are from the China and United States. Zhang Y is the author with the most published articles and holds the top position in the cited author h-index species. The journal with the highest number of published articles is “Disability and rehabilitation”; the journal is divided into four main areas including physics, materials, chemistry, molecular, and biology. The keyword analysis revealed a shift in research hotspots from schwann cell, fracture, and urinary disorders to carbon-based materials, functional recovery, and surgery. Analysis of qualitative data revealed that the role and mechanism of injectable conductive hydrogels in spinal cord healing after damage is a hot topic of current study, with the mechanism primarily focusing on the inhibition of oxidative stress (Nrf2) and apoptosis (Casepase 3).

Conclusion: Our bibliometric analysis indicates that research on electroactive materials for spinal cord injury remains an active field of study. Moreover, contemporary research is concentrated on carbon-based materials, functional rehabilitation, and surgery.
A three-dimensional actively spreading bone repair material based on cell spheroids can facilitate the preservation of tooth extraction sockets
Authors: Guo Xinwei , Zheng Huimin , Guo Yusi , Heng Boon Chin , Yang Yue , Yao Weitong , Jiang Shengjie
Published: February 2023

Introduction: Achieving a successful reconstruction of alveolar bone morphology still remains a challenge because of the irregularity and complex microenvironment of tooth sockets. Biological materials including hydroxyapatite and collagen, are used for alveolar ridge preservation. However, the healing effect is often unsatisfactory.

Methods: Inspired by superwetting biomimetic materials, we constructed a 3D actively-spreading bone repair material. It consisted of photocurable polyether F127 diacrylate hydrogel loaded with mixed spheroids of mesenchymal stem cells (MSCs) and vascular endothelial cells (ECs).

Results: Biologically, cells in the spheroids were able to spread and migrate outwards, and possessed both osteogenic and angiogenic potential. Meanwhile, ECs also enhanced osteogenic differentiation of MSCs. Mechanically, the excellent physical properties of F127DA hydrogel ensured that it was able to be injected directly into the tooth socket and stabilized after light curing. In vivo experiments showed that MSC-EC-F127DA system promoted bone repair and preserved the shape of alveolar ridge within a short time duration.

Discussion: In conclusion, the novel photocurable injectable MSC-EC-F127DA hydrogel system was able to achieve three-dimensional tissue infiltration, and exhibited much therapeutic potential for complex oral bone defects in the future.
Machine learning in concrete technology: A review of current researches, trends, and applications
Authors: Gamil Yaser
Published: February 2023

Machine learning techniques have been used in different fields of concrete technology to characterize the materials based on image processing techniques, develop the concrete mix design based on historical data, and predict the behavior of fresh concrete, hardening, and hardened concrete properties based on laboratory data. The methods have been extended further to evaluate the durability and predict or detect the cracks in the service life of concrete, It has even been applied to predict erosion and chemical attaches. This article offers a review of current applications and trends of machine learning techniques and applications in concrete technology. The findings showed that machine learning techniques can predict the output based on historical data and are deemed to be acceptable to evaluate, model, and predict the concrete properties from its fresh state, to its hardening and hardened state to service life. The findings suggested more applications of machine learning can be extended by utilizing the historical data acquitted from scientific laboratory experiments and the data acquitted from the industry to provide a comprehensive platform to predict and evaluate concrete properties. It was found modeling with machine learning saves time and cost in obtaining concrete properties while offering acceptable accuracy.
Biophysics at the edge of life and death: Radical control of apoptotic mechanisms
Authors: Hack Samantha J. , Beane Wendy S. , Tseng Kelly Ai-Sun
Published: February 2023

Recent studies have furthered our understanding of how dying and living cells interact in different physiological contexts, however the signaling that initiates and mediates apoptosis and apoptosis-induced proliferation are more complex than previously thought. One increasingly important area of study is the biophysical control of apoptosis. In addition to biochemical regulation, biophysical signals (including redox chemistry, bioelectric gradients, acoustic and magnetic stimuli) are also known yet understudied regulators of both cell death and apoptosis-induced proliferation. Mounting evidence suggests biophysical signals may be key targets for therapeutic interventions. This review highlights what is known about the role of biophysical signals in controlling cell death mechanisms during development, regeneration, and carcinogenesis. Since biophysical signals can be controlled spatiotemporally, bypassing the need for genetic manipulation, further investigation may lead to fine-tuned modulation of apoptotic pathways to direct desired therapeutic outcomes.
Bioengineered MSC-derived exosomes in skin wound repair and regeneration
Authors: Zhao Hanxing , Li Zhengyong , Wang Yixi , Zhou Kai , Li Hairui , Bi Siwei , Wang Yudong , Wu Wenqing , Huang Yeqian , Peng Bo , Tang Jun , Pan Bo , Wang Baoyun , Chen Zhixing , Zhang Zhenyu
Published: February 2023

Refractory skin defects such as pressure ulcers, diabetic ulcers, and vascular ulcers represent a challenge for clinicians and researchers in many aspects. The treatment strategies for wound healing have high cost and limited efficacy. To ease the financial and psychological burden on patients, a more effective therapeutic approach is needed to address the chronic wound. MSC-derived exosomes (MSC-exosomes), the main bioactive extracellular vesicles of the paracrine effect of MSCs, have been proposed as a new potential cell-free approach for wound healing and skin regeneration. The benefits of MSC-exosomes include their ability to promote angiogenesis and cell proliferation, increase collagen production, regulate inflammation, and finally improve tissue regenerative capacity. However, poor targeting and easy removability of MSC-exosomes from the wound are major obstacles to their use in clinical therapy. Thus, the concept of bioengineering technology has been introduced to modify exosomes, enabling higher concentrations and construction of particles of greater stability with specific therapeutic capability. The use of biomaterials to load MSC-exosomes may be a promising strategy to concentrate dose, create the desired therapeutic efficacy, and maintain a sustained release effect. The beneficial role of MSC-exosomes in wound healing is been widely accepted; however, the potential of bioengineering-modified MSC-exosomes remains unclear. In this review, we attempt to summarize the therapeutic applications of modified MSC-exosomes in wound healing and skin regeneration. The challenges and prospects of bioengineered MSC-exosomes are also discussed.
Roles of STAT3 in the pathogenesis and treatment of glioblastoma
Authors: Fu Weijia , Hou Xue , Dong Lihua , Hou Wei
Published: February 2023

Glioblastoma (GBM) is the most malignant of astrocytomas mainly involving the cerebral hemispheres and the cerebral cortex. It is one of the fatal and refractory solid tumors, with a 5-year survival rate of merely 5% among the adults. IL6/JAK/STAT3 is an important signaling pathway involved in the pathogenesis and progression of GBM. The expression of STAT3 in GBM tissues is substantially higher than that of normal brain cells. The abnormal activation of STAT3 renders the tumor microenvironment of GBM immunosuppression. Besides, blocking the STAT3 pathway can effectively inhibit the growth and metastasis of GBM. On this basis, inhibition of STAT3 may be a new therapeutic approach for GBM, and the combination of STAT3 targeted therapy and conventional therapies may improve the current status of GBM treatment. This review summarized the roles of STAT3 in the pathogenesis of GBM and the feasibility of STAT3 for GBM target therapy.
Coordinated regulation of Cdc42ep1, actin, and septin filaments during neural crest cell migration
Authors: Kho Mary , Hladyshau Siarhei , Tsygankov Denis , Nie Shuyi
Published: February 2023

The septin cytoskeleton has been demonstrated to interact with other cytoskeletal components to regulate various cellular processes, including cell migration. However, the mechanisms of how septin regulates cell migration are not fully understood. In this study, we use the highly migratory neural crest cells of frog embryos to examine the role of septin filaments in cell migration. We found that septin filaments are required for the proper migration of neural crest cells by controlling both the speed and the direction of cell migration. We further determined that septin filaments regulate these features of cell migration by interacting with actin stress fibers. In neural crest cells, septin filaments co-align with actin stress fibers, and the loss of septin filaments leads to impaired stability and contractility of actin stress fibers. In addition, we showed that a partial loss of septin filaments leads to drastic changes in the orientations of newly formed actin stress fibers, suggesting that septin filaments help maintain the persistent orientation of actin stress fibers during directed cell migration. Lastly, our study revealed that these activities of septin filaments depend on Cdc42ep1, which colocalizes with septin filaments in the center of neural crest cells. Cdc42ep1 interacts with septin filaments in a reciprocal manner, with septin filaments recruiting Cdc42ep1 to the cell center and Cdc42ep1 supporting the formation of septin filaments.