bluuebunny/crossref_metadata_2025 huggingface dataset:
Servitisierung im Rahmen der Fabrikplanung/Industrial challenges and needs for service integration in the context of factory planning
Authors: Burggräf Peter , Adlon Tobias , Beyer Moritz , Koc Rana
Published: January 2023

Cyber-Physische-Produkt-Service-Systeme (CPSS) bilden die Grundlage zur Befähigung von Industrie 4.0 Use-Cases. Unter diese fallen auch digitale, vernetzte und intelligente Services, welche im Rahmen des Fabrikbetriebes Anwendung finden. Auf einem anbietergetriebenen Markt werden Services von Providern heutzutage in die Fabrik „gepusht“. Die Betrachtung der Service-Dimension aus der Planungsperspektive („Pull“) einer Fabrik findet in der Theorie und Praxis wenig Beachtung. Es wurden Bedarfe identifiziert, das Themenfeld in der Fabrikplanung der Zukunft zu verankern.

 

Cyber-physical product service systems (CPSS) form the basis for enabling Industrie 4.0 use cases. These include digital, networked and intelligent services that are consumed as part of factory operations. In a provider-driven market, services are nowadays „pushed“ into the factory by providers. Consideration of the service dimension from the planning perspective („pull“) of a factory receives little attention in theory and practice. Needs have been identified to anchor this topic in the factory planning of the future.
Additive Fertigung individualisierter Sensorgehäuse/Additive manufacturing of individualised sensor housings
Authors: Pfeffer Stefan , Springer Patrick , Granse Tobias , Neff Martin , Leitl Simon , Dorneich Albert , Fritton Markus , Geiger Frank
Published: January 2023

Induktive Sensoren werden in Einschraubgehäusen als Standardkomponenten eingesetzt. In einem Verbund aus Fraunhofer-Institut für Produktionstechnik und Automatisierung IPA sowie den Firmen Arburg GmbH und Balluff GmbH wurde ein Ansatz entwickelt, um derartige Sensoren in individualisierbaren Gehäusen zu fertigen. Dieser Beitrag beschreibt wie Gehäuse additiv gefertigt und vergossen werden können. Zusätzlich werden Ergebnisse industrieller Qualifikationstests zur Evaluation der Sensoren beschrieben.

 

Inductive sensors are used in screw-in housings as standard components. In an alliance of Fraunhofer IPA and the companies Arburg GmbH und Co. KG and Balluff GmbH, an approach was developed to manufacture such sensors in customizable housings. The publication describes how housings can be additively manufactured and molded. In addition, results of industrial qualification tests for the evaluation of the sensors are described.
Überwachung der Randzone beim Unrundschleifen/Method for monitoring the workpiece‘s surface integrity during non-circular grinding
Authors: Rößler Maximilian , Jedamski Rahel , Heinzel Jonas , Karpuschewski Bernhard , Epp Jérémy , Dix Martin
Published: January 2023

Die gezielte Einstellung von Randzoneneigenschaften (unter anderem Eigenspannungszustand) beim Unrundschleifen stellt eine Herausforderung dar. In der vorliegenden Arbeit wird die kombinierte Anwendung eines auf dem mikromagnetischen Barkhausenrauschen basierenden Messsystems und einer thermischen Prozessgrenze zur Detektion lokaler Randzonenbeeinflussungen beim Unrundschleifen untersucht. Das Barkhausenrauschsignal wird unter Berücksichtigung der variierenden Bauteilkrümmung ausgewertet.

 

The adjustment of the surface and subsurface state (e.g. residual stresses) during non-circular grinding is challenging. In the present work, the combined application of a measurement system based on the micromagnetic Barkhausen noise and a thermal process limit for the detection of local near-surface disturbances during non-circular grinding is investigated. The Barkhausen noise signal is evaluated considering the varying workpiece curvature.
Einfluss von Spanleitstufen auf die Oberfläche/Thermomechanical aspects in turning of high-strength aluminum alloys – Influence of chip breaker on the surface
Authors: Schubert Andreas , Nestler Andreas , Junge Thomas , Lampke Thomas , Mehner Thomas
Published: January 2023

Das Einsatzverhalten von Bauteilen wird von deren Oberflächenzustand bestimmt. In diesem Zusammenhang haben bei der spanenden Endbearbeitung die Werkzeuggeometrie und der daraus resultierende Spanfluss beziehungsweise -bruch eine große Bedeutung. Im Rahmen der experimentellen Untersuchungen werden die Auswirkungen der Spanleitstufengeometrie auf Temperaturen und Kräfte beim Drehen der Aluminiumlegierung EN AW-2017 sowie die resultierenden Eigenspannungen und die Oberflächenrauheiten vertieft betrachtet.

 

The performance of parts is significantly influenced by their surface condition. In this context, the tool geometry and the resulting chip flow or chip breakage are of great importance in finish machining. The experimental investigations focus on the impact of the chip breaker geometry considering temperatures and forces during turning of the aluminum alloy EN AW-2017 as well as the resulting residual stresses and surface roughness.
Steigerung der Datenqualität in der Montage/Checklist for measurement and data planning in machine learning – Increasing data quality in assembly lines
Authors: Schnur Christopher , Klein Steffen , Blum Anne , Schütze Andreas , Schneider Tizian
Published: January 2023

Daten sind eine wichtige Grundlage für die Anwendung von maschinellem Lernen (ML) in der Industrie, zum Beispiel für die Zustandsbewertung in der Montage. Insbesondere bei Brownfield-Anlagen ist die Datenqualität für einen zuverlässigen Einsatz von ML-Methoden häufig nicht ausreichend. Im Rahmen dieses Beitrags wird eine open-source Checkliste, basierend auf dem CRISP-DM Referenzmodell, vorgestellt, die die kritischen Punkte bei ML-Projekten abdeckt und so die Datenqualität sicherstellen und steigern soll.

 

Data is an important basis for the application of machine learning (ML) in industry, e.g., for condition monitoring in assembly lines. Especially in brownfield systems, the data quality is often not sufficient for a reliable application of ML algorithms. This paper presents an open-source checklist, based on the established CRISP-DM reference model, covering critical points in machine learning projects to ensure data quality.
Werkzeugintegrierte Dünnschichtsensorik/Tool-integrated thin-film sensors – Temperature, force and wear measurement for the digitalization of cutting processes
Authors: Plogmeyer Marcel , González Germán , Schulze Volker , Bräuer Günter
Published: January 2023

Mit Dünnschichtsensoren werden die Temperaturen, Kräfte und der Werkzeugverschleiß in Zerspanungsprozessen in unmittelbarer Nähe zur Wirkzone erfasst. Dadurch können zum einen analytische Modelle zur Beschreibung von Randschichtzuständen präzise kalibriert werden. Zum anderen kann mit den in-process erfassten Kenngrößen ein sogenannter Softsensor zur Regelung der Prozessstellgrößen implementiert werden, um gezielt Randzoneneigenschaften des Werkstücks einzustellen.

 

Thin film sensors are used to record temperatures, forces and tool wear in machining processes in the immediate vicinity of the contact zone between tool and workpiece. On the one hand, this makes it possible to precisely calibrate analytical models for describing boundary layer conditions. On the other hand, the parameters recorded in-process can be used to implement a so-called soft sensor for controlling the process parameters in order to specifically adjust the properties of the subsurface layer of the workpiece.
In-situ Materialanalyse mit Mikromagnetik und ML-Verfahren/In-situ material analysis with micromagnetics and ML methods – Detection of quality-critical features on AISI4140 with micromagnetic NDT
Authors: Böttger David , Strass Benjamin , Wolter Bernd , Güray Alpan , Gauder Daniel , Schulze Volker , Lanza Gisela
Published: January 2023

In diesem Beitrag wird das Detektionsvermögen der in-situ Hochgeschwindigkeits-3MA-Prüftechnik hinsichtlich qualitätskritischer Merkmale an AISI4140 mittels maschineller Lernverfahren wie der kanonischen Diskriminanzanalyse (CDA) und die Bewertung von dessen in-situ Fähigkeit erläutert. Abschließend wird das Potenzial in Bezug einer Steuerung und Regelung des Prozesses mithilfe von Softsensorik gezeigt.

 

The detection capability of the in-situ high-speed 3MA inspection technique with respect to quality-critical features on AISI4140 using maschine learning techniques such as canonical discriminant analysis (CDA) and the evaluation of its in-situ capability are shown. The potential regarding control and regulation of the process by means of softsensors is shown in conclusion.
Funktionalisieren von Faser-Kunststoff-Verbunden/Functionalized fiber-reinforced plastic composites
Authors: Franke Volker , Gebauer Jana
Published: January 2023

Im Projekt „Chimera“ wird zur Gewichtsreduktion im Fahrzeugbau ein faserverstärktes Kunststoffbauteil auf innovative Weise mit metallischen Eigenschaften versehen. Durch die Kombination zweier Teilprozesse, dem Laserstrukturieren und dem thermischen Spritzen, sollen optimale Verbundfestigkeit und Langzeitbeständigkeit hergestellt werden. Demonstrator im Projekt ist ein Gehäusebauteil zur elektromagnetischen Abschirmung in einem Elektrofahrzeug.

 

Within the “Chimera“ project weight reduction for automotive applications is addressed by further development of fiber-reinforced plastic components which are functionalized by means of metallic coatings. By combining two sub-processes, laser structuring and thermal spraying, optimized bond and composite strength as well as long-term durability will be realized. The project demonstrator is a housing component for electromagnetic shielding in an electric vehicle.
ANALISIS HUKUM ISLAM TERHADAP PERBEDAAN PEMAHAMAN TENTANG NIKAH KEKERABATAN
Authors: Nilhakim
Published: January 2023

The purpose of this research is to know how the concept of kinship marriage in Islamic law. The research method used is the content analysis method, with the primary source being the source of Islamic law (hadith) regarding the prohibition of marrying a woman who is still a family relationship. analysis steps, namely: first, formulate the problem to be studied. Second, the author determines the authenticity of the hadith as a source of Islamic law. Furthermore, in the third step, the author categorizes the views of the ulama on the argument of the hadith regarding the prohibition of marrying a woman who is still a family relationship. Furthermore, the data is described. The trick is to compare the opinions of the scholars about the hadith prohibiting marriage with women who are still related to the family. The results showed that, the prohibition of marrying a woman who is still a family relationship, the textual text of the original law is that it is permissible to marry her.
VALIDITAS HADIS TENTANG JUAL BELI GHARAR
Authors: Hamnah Hamnah
Published: January 2023

The Qur'an is a source of Islamic law that is Qath'I, where all of its people must obey the laws that exist in it and no one disagrees or refutes it. Hadith is a source of Islamic teachings, which is second to the Qur'an. From the point of view of the narration, it is clear that there is a difference between the Hadith and the Qur'an. For the Qur'an, all its narrations are mutawatir. While the narration of Hadith takes place in part mutawatir and partly takes place on a week. So starting from here arise various opinions in assessing the quality of hadith.            Hadith, even though it is the second source of Islamic law, is still disputed by scholars about its validity to be used as a legal basis, especially those related to vague cases both in the fields of aqidah, worship and muamalah. Currently, what is being discussed a lot is about the validity of the hadith in terms of trade law (buying and selling), especially vague buying and selling (gharar) because it will have an impact on aspects of the sale and purchase results are halal or haram to be used (used and eaten).            The validity of this hadith in terms of buying and selling gharar needs to be re-analyzed in terms of its narration, which is related to the sanad and matan aspects. Hadith can only be said to be the second source of Islamic law when its quality is valid, both in terms of sanad and matan. A hadith can only be said to be valid if it meets the criteria for the validity of the hadith sanad, namely: the chain is continued, the narrator is 'fair, the narrator is dhabit, avoids syaz and avoids 'illat. In addition to the validity of the sanad, the validity of the matan is also important to prove the quality of a hadith, according to the jurists, the rules of the validity of the matan hadith are: Not maqlub, not mudraj, not experiencing ziyadah al-Tsiqah, not mudhtarib and not mushahhaf and muharraf.
STATUS PERJANJIAN HUTANG PIUTANG YANG DILAKUKAN OLEH RENTENIR SEBAGAI KREDITUR DITINJAU DARI FIKIH MUAMALAH ( Studi Kasus Pada Putusan Nomor 202/Pdt.G/2020/PN Mlg )
Authors: Hambali Muhammad
Published: January 2023

Beberapa tahun terahir perkembangan perekonomian Islam sangat pesat sekali. Kemudian untuk mengikuti perkembangan perekonomian yang berbasis Islam tersebut berdirilah lembaga keuangan syariah dengan system pengolaan yang sesuai dengan syaiat. Tetapi masih saja banyak masyarakat yang melakukan transaksi hutang piutang kepada rentenir dengan tidak adanya kesepakatan yang jelas tentu dengan pengembalian dengan tambahan yang besar. Hal seperti ini sangat meresahkan, dan banyak menimbulkan kerugian kepada debitur. Penelitian ini berfokus pada kasus yang ada dalam putusan Nomor 202/Pdt.G/2020/PN Mlg. Penelitian ini dilakakukan dengan menggunakan pendekatan literature review hutang piutang dalam fikih muamalah. Kemudian dianalisa dengan materi-materi yang telah ada sehingga dapat menguraikan permasalahan ini dengan jelas. Suatu hutang piutang yang dilakukan seseorang harus mempunyai perjanjian yang jelas. Baik perjanjian itu dilakukan secara lisan maupun dengan cara tertulis dengan menghadirkan sejumlah saksi. Sangat banyak sekali manfaat yang didapat jika suatu hutang piutang dituangkan dalam tulisan. Semua itu dijelaskan secara langsung dalam QS. Al Baqarah Ayat 282 yang terkenal dengan ayat Muamalah.
EMAS SEBAGAI INSTRUMEN INVESTASI JANGKA PANJANG
Authors: Nudia Dina
Published: January 2023

Penelitian ini mengobservasi hubungan kebijakan moneter dengan investasi emas di Indonesia dalam  jangka panjang.Penelitian ini bertujuan untuk mengetahui kapan waktu yang tepat untuk berinvestasi emas. Emas suatu benda yang sangat bernilai. Berinvestasi emas merupakan salah satu langkah tepat untuk menghindari kerugian akibat dari perekonomian yang terkadang tidak menentu, invetasi emas merupakan instrument investasi yang rendah resiko, emas merupakan pilihan lindung nilai yang baik karna emas tidak terpengaruh kepada inflasi.Selama berabad-abad telah diakui sebagai logam mulia, yang mendapatkan tempat tertinggi sebagai pilihan investasi masyarakat. Logam mulia tersebut banyak dipilih karena mayoritas masyarakat telah familiar terhadap emas serta mudah dijangkau. Selain itu, dikarenakan harga emas cenderung stabil dan jarang mengalami penurunan harga, justru saat ini mengalami peningkatan harga dalam waktu yang singkat. Perlindungan hukum bagi para investor emas telah diatur oleh Otoritas Jasa Keuangan (OJK).
ANALISIS FAKTOR-FAKTOR YANG MEMENGARUHI INDEKS PEMBANGUNAN MANUSIA DALAM PEMBANGUNAN EKONOMI DI KALIMANTAN BARAT
Authors: Sukmawati U. Sulia , Ana Putri , Trisna Deea
Published: January 2023

Kualitas Manusia sangat penting untuk diperhatikan oleh pemerintah, untuk meningkatkan pembangunan ekonomi. Adapun kualitas sumbaer daya manusia dapat dilihat melalui beberapa indikator diantaranya pendidikan dan kesehatan. Pendidikan merupakan faktor utama dalam membangun daerah bahkan bangsa, sehingga tinggi rendahnya indeks pendidikan memberikan salah satu indikator dalam kemajuan suatu daerah. Sedangkan, kesehatan merupakan modal awal dan paling penting bagi manusia untuk melaksanakan kehidupan sosial ekonomi. Pendidikan dan kesehatan menjadi salah satu kunci untuk meningkatkan kualitas sumber daya manusia dimasa pendemi Covid-19 sekarang ini, karena tanpa pendidikan dan kesehatan manusia tidak akan bisa untuk tumbuh dan berkembang untuk meningkatkan perekonomian diri, keluarga maupun wilayahnya. Sehingga, Tujuan dari penelitian yaitu ingin mengetahui bagaimana pengaruh tingkat pendidikan dan kesehatan terhadap kualitas sumber daya manusia dan dapat menjadi roda penggerak di dalam proses pembangunan manusia yang lebih baik lagi dengan kata lain sumber daya manusia yang lebih berkualitas khusunya Kalimantan Barat. Metode yang digunakan di dalam penelitian ini adalah penelitian kuantitatif dengan pendekatan elucidation dengan menggunakan studi literatur. Hasil penelitian menunjukan bahwa tingkat pendidikan dan kesehatan menjadi penggerak indeks pembangunan manusia ini bersifat benar bahwasanya jika aspek pendidikan dan kesehatan suatu daerah sudah maksimal dirasa indeks pembangunan manusia juga dirasa akan maksimal. Dengan demikian dampak penelitian ini adalah proses pembangunan aspek pendidikan dan kesehatan yang di laksanakan secara maksimal akan mendapatkan hasil yang maksimal pula untuk indeks pembangunan manusia yang ada di Kalimantan Barat.
CYTOLOGICAL CHARACTERISTICS OF EXPERIMENTAL PURULENT NON-HEALING WOUNDS IN THE TREATMENT OF SILVER NANOPARTICLES
Authors: Myronov P. F. , Bugaiov V. I. , Medvedieva I. M. , Myronova M. M. , Gift A. B.
Published: January 2023

Summary. The purpose of the work is to conduct a cytological examination of swabs-imprints of experimental purulent wounds that have not healed for a long time, when treated with silver nanoparticles in comparison with 0.05 % Chlorhexidine solution.

Research materials and methods. The study of the features of the cytological picture of skin regeneration was carried out on 60 white non-linear laboratory rats.

Research results. The obtained results of the cytological examination of purulent wounds that did not heal for a long time indicate faster wound healing processes in the group using nanostructured silver compared to the control group: there was a faster decrease in the number of leukocytes in the field of view and the percentage of their destruction, faster activation of monocyte-macrophage cells series, the appearance of fibroblasts and epithelial cells and, as a result, a faster change in the types of cytograms from necrotic to regenerative.

Conclusions. It was established that the presented method of using nanostructured silver contributes to a better elimination of microbial insemination, leads to a significant decrease in the number of neutrophil leukocytes and leukocytes in the stage of destruction, an increase in the percentage of phagocytic leukocytes, fibrocytes, fibroblasts, endotheliocytes and epithelial cells, which indicates a better antibacterial and anti-inflammatory effect and indicates much faster processes of cleaning and regeneration of purulent wounds. The use of silver nanoparticles has significant advantages compared to traditional treatment with a 0.05 % solution of Chlorhexidine and is promising for use in the practice of purulent surgery.
INTRAOPERATIVE SIGNS OF ACUTE BILIARY PANCREATITIS
Authors: Vasyliuk S. M. , Prudnikov O. V. , Ivanyna V. V. , Tkachuk O. S. , Pavliuk N. M. , Krysa B. V. , Atamaniuk V. M.
Published: January 2023

Summary. Introduction. According to the opinion of a number of experts, acute biliary pancreatitis should be considered a combination of acute pancreatitis with chronic or acute diseases of the biliary tract.

Aim. To assess intraoperative morphological changes during laparoscopy in patients with acute biliary pancreatitis.

Materials and methods. We treated 65 patients with acute biliary pancreatitis who had isolated cholecystolithiasis. Forty-two patients had acute calculous cholecystitis, twenty-three patients had chronic calculous cholecystitis. All patients underwent laparoscopy, which included diagnostic and treatment stages.

Results. Signs of acute biliary pancreatitis were: serous fluid (6.2 %), fibrinous fluid (10.8 %), hemorrhagic fluid (41.5 %), fatty spots (7.7 %), mesenteric hemorrhagic edema of the large intestine (64.6 %), pancreas edema (23.1 %), omentum edema (50.8 %), vitreous edema of the hepatoduodenal ligament (36.9 %), enlarged gallbladder (60.0 %), destructive acute cholecystitis (9.2 %). When the head of the pancreas was damaged, we observed hemorrhagic fluid, hepatoduodenal ligament edema, an enlarged gallbladder, and acute cholecystitis. When the body of the pancreas was damaged, we observed serous fluid, fatty spots, mesenteric edema of the large intestine, and parapancreatic infiltrate. In the inflammatory process of the pancreas tail, we often observed fibrinous fluid in the abdominal cavity.
DIAGNOSTIC MONITORING OF TRAUMATIC LIVERIN JURIES
Authors: Kapshitar O. V. , Tantsura P. Yu. , Kapshitar O. О.
Published: January 2023

Summary. Goal. Develop tactics for diagnostic monitoring of traumatic liver injuries.

Materials and methods of research.The study is based on an analysis of 56 victims with liver damage. A set of studies, including clinical, laboratory, and instrumental methods, was used to examine victims with abdominal injuries.

Research results and their discussion.The tactics of treatment for patients were primarily determined by the results of ultrasound and CT scans. Diagnostic monitoring was carried out in several stages: the first immediately after hospitalization in the admission department or intensive care unit, then, as is, taking into account the data found during the initial examination. The decision to choose conservative tactics was made within the first 3 hours after admission to the clinic. In the future, the patient’s management tactics will be determined depending on the severity of his condition, volume of hydroperitoneum, the intensity of blood loss, and hemodynamic parameters. In the case of hematomas of the liver, in the absence of signs of hydroperitoneum and stable hemodynamics, conservative therapy was performed with dynamic instrumental control over the condition of the hematoma.

Conclusions. Predicting the outcome of liver damage largely depends on the correct choice of methods of instrumental diagnosis and consistency in the analysis of information obtained from dynamic monitoring. This makes it possible to predict the severity of the condition and tactics of the patient, expanding the indications for conservative therapy. Conservative tactics are allowed only with repeated instrumental monitoring.
OPTIMIZATION OF TREATMENT OF PATIENTS WITH PANCREATIC CANCER COMPLICATED BY MECHANICAL JAUNDICE
Authors: Parkhomenko K. Yu. , Drozdova A. G. , Payunov K. Ye. , Shadrin O. V.
Published: January 2023

Summary. The aim of the study was to improve the results of surgical treatment of patients with malignant neoplasms of the pancreas complicated by mechanical jaundice, as well as to prove the feasibility of combined treatment and staged approach to it using minimally invasive technologies.

Materials and methods of the study. The results of treatment of 112 patients with pancreatic cancer who were treated in the surgical department of the Municipal non-commercial enterprise of the Kharkov regional council «Regional Clinical Hospital» from 2018 to 2021 were analyzed. The age of the examined patients averaged (53,2 ± 12,7) (from 37 to 88 years), of which women — 43 (38,0 %), men — 69 (62,0 %). All patients were examined in the laboratory and instrumentally.

Results of the study. Mechanical jaundice was observed in 81 (72,0 %) patients. According to the classification of VE Smirnov (1974), in 16 (14,2 %) patients acute jaundice was observed, in 56 (50 %) — acute prolonged and in 40 (35,8 %) — chronic mechanical jaundice. Among the results of the study of the analyzed patients, the minimum level of total bilirubin in mechanical jaundice was 44 μmol/l, the maximum — 546 μmol/l. All patients with mechanical jaundice underwent endoscopic retrograde cholangiopancreatography. Eight (9,8 %) patients developed complications after endoscopic retrograde cholangiopancreatography: bleeding from a papillotomy wound (4), clinic of acute pancreatitis (3), injury of the posterior wall of the duodenum (1). In 2 cases, the procedure failed due to total obstruction of the large duodenal nipple. Among the 79 patients who managed to undergo endoscopic intervention, only 5 cases, according to the commission on cancer care, were recognized as resectable in the future.

Conclusions. Minimally invasive methods of restoring bile in mechanical jaundice caused by cancer of the pancreas are effective as independent treatment procedures, staged, which may precede laparotomy.
THE ROLE OF ENDOSCOPIC ULTRASONOGRAPHY IN THE DIAGNOSIS OF CYSTIC FORMULATIONS OF THE PANTACRATIC GLAND
Authors: Нoncharov A. S. , Нoncharova N. M. , Teslenko S. M.
Published: January 2023

Summary. Differential diagnosis of cystic lesions of the pancreas remains one of the most problematic sections of abdominal surgery. Endoscopic ultrasonography is gaining more and more importance in the diagnosis and determination of treatment tactics of cystic lesions.

The goal is to determine the place of endoscopic ultrasonography in the diagnosis of patients with cystic lesions of the pancreas.

Materials and methods. Analyzed literary sources that were devoted to the use of endoscopic ultrasonography for the diagnosis of cystic lesions of the pancreas.

Results and their discussion. Endoscopic ultrasonography, thanks to its high resolution and the absence of interposition of air-containing organs, allows you to visualize both the characteristic features of the structure of the cystic tumor itself and the ductal system of the pancreas, as well as to evaluate the thickness of the cyst wall, the presence of intracystic membranes and a solid component, the nature of the contents, the number of cystic cavities in the lesions.

Conclusions. Endoscopic ultrasonography is a clarifying method of diagnosis, which should be used in all patients at the stages of examination, planning treatment tactics and choosing a surgical intervention method.
OPTIMIZATION OF SURGICAL TACTICS IN PATIENTS WITH POSTNECROTIC PANCREATIC CYSTS
Authors: Merkulov A. O. , Shevchenko O. M.
Published: January 2023

Summary. The predominance of people of working age (21–60 years) among patients with pancreatic necrosis, the occurrence of permanent disability in a significant part of patients, high overall and postoperative mortality (20–85 %), due to various complications, turns the treatment of pancreatic necrosis into an important social problem. The frequency of formation of false cysts in acute pancreatitis is 5–16 %, and in destructive forms it increases to 60–80 %.

Materials and methods. The scope of endoscopic interventions in the treatment of 16 patients with pancreatic cysts of the pancreas directly depended on the preoperative findings and, first of all, on the presence of the connection of the cyst with the pancreatic ducts. Favorable conditions for endoscopic correction in the treatment of pancreatic pseudocysts were a small (less than 10 mm) distance between their cavity and the lumen of the gastrointestinal tract, minimal thickness of the capsule (no more than 2 mm), large dimensions (over 6 cm), as well as localization in the projection body and isthmus of the pancreas.

Research results. When analyzing the results of the treatment of complications of pancreatic necrosis, we formulated an algorithm for the rational choice of operative interventions. We believe that rational treatment is based on early diagnosis of PN complications, including hemorrhagic ones.

Conclusions. The use of the developed algorithm allowed us to reliably reduce postoperative mortality among patients of this category.
ADVANTAGES OF VAC POSTOPERATIVE ABDOMINAL WALL WOUND COMPLICATIONS TREATMENT IN CANCER PATIENTS
Authors: Lykhman V. M. , Ketsman R. V. , Postolov O. M. , Chemadura V. Yu. , Ievtushenko D. V. , Osokin A. E. , Levenets T. V. , Suprun O. S. , Bogodenko K. S.
Published: January 2023

Summary. Introduction. Postoperative abdominal wall wound infevtions became significant problem om modern surgery impacting approximatly 110,800 patients in 2015.

Aim of study. Comparison of postoperative abdominal wall wound complications treatment methods in cancer patients.

Materials and method. 24 cases of patients with purulent-septic complications of postoperative wounds were analised. 10 (41,6 %) — men and 14 (58,4 %) — women. The average age of patients was 63,8±17,1 years. Patients were divided into two groups: a comparative group — 12 patients (routine treatment), and an experimental group — 12 patients, which was treated using the VAC system. Both groups received infusion and antibacterial therapy.

Research results. In cultures of wound contents, the following were found: (1) Staphylococcus aureus — 38,9 %, (2) Staphylococcus epidermidis — 19,5 %, (3) Enterococcus faecalis — 19,1 %, (4) Escherichia coli — 15,4 %, (5) Pseudomonas aeruginosa — 5,8 %, (6) Proteus vulgaris — 0,9 %, as well as (7) gram-positive aerobic and facultatively anaerobic pathogens — 0,4 %.

According to the results of bacteriological examination of the wound contents in the patients of the experimental group, the microbial count decreased statistically significantly (to 105-106, p>0,05) starting from the third day of treatment. In the comparative group — all indicators remained at the previous levels (108-109).

Conclusions. VAC-therapy appeared superior in postoperative abdominal wall wound complications treatment in cancer patients. VAC significantly reduces both duration of hospital stay and mortality.
THE RELATIONSHIP BETWEEN CENTRAL BLOOD FLOW AND MICROCIRCULATION WITH THE AMOUNT OF ELASTIC COMPRESSION IN POST-THROMBOPHLEBOTIC SYNDROME IN THE STAGE OF DECOMPENSATION
Authors: Rusyn V. I. , Pavuk F. M. , Fedusyak V. Yа.
Published: January 2023

Summary. Aim. To determine the influence of elastic compression on the venous and arterial velocity of the main blood flow of the lower limb and the skin microcirculation of the anterior part of the foot in patients with a decompensated form of postthrombophlebotic syndrome.

Materials and methods. 21 patient with post-thrombophlebotic syndrome in the stage of decompensation participated in the study. Among them were 12 (57 %) women and 9 (43 %) men. The average age of the patients was (58.5±6.4) years. All subjects of the study were measured for the ankle-brachial pressure index, deep femoral-popliteal index, regional perfusion index, tcpO2, tcpCO2, arterial blood flow velocity in the femoral artery, and venous blood flow velocity distal to the saphenofemoral junction. After the measurements, the following measurements were performed after using elastic medical knitwear of different compression classes.

Research results. With I class compression, the venous blood flow rate was (0.064±0.007) (p=0.0001). The venous velocity of the femoral blood flow significantly decreased, on average, by 7.4 times compared to the initial conditions when using class IV compression (p=0.0001). values of tcpCO2 increased significantly already at the 1st compression class. (p=0.0001) and continued to increase until the end of the study. Analyzing the changes in tcpO2 and tcpCO2, it was established that at the 3rd compression class, there was a cross between the oxygen and carbon dioxide tension indicators, which was accompanied by the predominance of tcpCO2 pressure over tcpO2 at the next increase in the compression class.

Conclusions. The arterial blood flow rate decreased by 8.5 times compared to the input data at the maximum pressure of the fourth compression class (p=0.0001). Venous velocity of blood flow in the femoral vein at the maximum pressure of elastic compression decreased venous velocity by 7.4 times compared to the initial normal (p=0.0001). tcpCO2 significantly increases at compression of 15 mmHg (p=0.0001).
ANALYSIS OF POSTOPERATIVE COMPLICATIONS IN THE TREATMENT OF PATIENTS WITH LUNG CANCER
Authors: Trunov G. V. , Havrylov A. Yu. , Petrychenko S. R.
Published: January 2023

Summary. The aim of the study. Based on the analysis of the nature and course of postoperative complications in the treatment of patients with lung cancer, to improve the results of surgical treatment of this category of patients.

Materials and methods. The results of the analysis of postoperative complications of 363 patients with lung cancer who were treated in the oncological department of the thoracic cavity of the clinic of the Communal Non-Commercial Enterprise «Regional Center of Oncology» in Kharkiv for the period from 2017 to 2021 are presented. There were 234 men (64.6 %) , women - 128 (35.4 %), the age of patients ranged from 43 to 84 years, the average age was (59.8±2.4 years). All patients underwent radical surgery for primary lung cancer. Lobectomies were performed most often. In this volume, 296 patients were operated on, which was 81.5 %. Pneumonectomy was performed on 51 patients, which was 14.1 %. Anatomical segmentectomy was performed in 16 patients (4.4 %). Postoperative complications and factors causing them were analyzed.

Research results and their discussion. The main complications typical for the postoperative period of lung cancer patients are highlighted. Complications in the postoperative period occurred in 10.5 % of patients. Complications related to failure of bronchus stump sutures and tracheobronchial tree anastomoses occurred in 8 patients (2.2 %). In two patients, this led to the development of pleural empyema and death.Thanks to early diagnosis, 4 patients underwent rethoracotomy, bronchus stump suturing, resection or final pneumonectomy.

Cardiovascular complications (acute myocardial infarction, acute cardiovascular failure, stroke, pulmonary embolism) were found in 5 patients (1.4 %). 3 patients died of stroke, acute myocardial infarction and acute cardiovascular failure. Two patients survived, and one of them was diagnosed with Pulmonary embolism (PE), COVID-19 and bilateral pneumonia.

Postoperative mortality was 2.5 % (9 patients died). Two patients (0.6 %) died from failure of the bronchus stump sutures, which led to empyema of the pleura. Two patients (0.6 %) died from the consequences of intrapleural bleeding. Another 2 (0.6 %) patients died of acute myocardial infarction. One patient each (0.3 %) died of stroke, postoperative pneumonia, and pericux abscess, which led to empyema of the pleura.

Conclusions. The surgical method of treating patients with lung cancer remains the main one despite the number of postoperative complications, the majority of which are «non-surgical». Analysis of the nature and course of postoperative complications in the treatment of patients with lung cancer, and the improvement of the method of determining functional operability, made it possible to reduce the frequency of complications and form a concept for improving the results of surgical treatment of this category of patients.
RISKS OF DEVELOPMENT OF ANASTOMOTIC SUTURE FAILURE DEPENDING ON THE METHOD OF DISSECTION OF THE TISSUES OF THE ORGANS OF THE GASTROINTESTINAL TRACT AND THE FEATURES OF THEIR FORMATION
Authors: Tsivenko O. I. , Bichkov S. O. , Grynyov R. M. , Dushyk L. M. , Cherkova N. V.
Published: January 2023

Summary. The purpose of the study: experimental and clinical study of the peculiarities of the course of reparative processes in the area of gastro- and colostomy wounds after carrying out various types of dissection and justification of the technique of forming anastomoses of the gastrointestinal tract.

Research materials and methods. The paper presents the results of an experimental and clinical study of the processes occurring in the area of gastro-, entero-, and colostomy wounds made with electrosurgical or ultrasonic scalpels, immediately after exposure to tissues and within thirty days.

Research results. Data were obtained that indicate a significant difference in destructive and reparative processes after various types of dissection. The use of ultrasonic dissection made it possible to maximally reduce ischemia of tissues and the internal ridge of anastomoses, in connection with which the reparative processes proceeded favorably and the patency through the anastomosis was not disturbed. The obtained results made it possible to scientifically substantiate the necessary distance of the needle from the edge of the dissection, depending on the type of dissection of the wall of the gastrointestinal tract.

Conclusions. Ultrasonic dissection of the gastrointestinal tract is characterized by a relatively gentle effect on biological tissues, which is accompanied by the formation of much smaller areas of necrosis and necrobiosis than with electrosurgical exposure. In addition, biological welding of the edges of the wound, reliable hemostasis is achieved; there are no carbonization of fabrics, their sticking to the surface of the manipulator, smoke, sparks and other effects.

It was established that after electrosurgical dissection, the phenomenon of prolonged necrosis develops, i.e., the necrosis zone spreads within three days, including due to the necrobiosis zone. This fact must be taken into account when applying seams.

Adherence to the technical rules for the formation of gastrointestinal anastomoses, based on experimental data, made it possible to eliminate the risks of developing postoperative complications, first of all, their failure.
PATHOMORPHOLOGICAL ASPECTS OF THE PERITONEAL CAVITY ADHESION PROCESS DEVELOPMENT I N ACUTE SURGICAL PATHOLOGY
Authors: Polyovyy V. P. , Sydorchuk R. I. , Savchuk A. Yu. , Palyanytsia A. S. , Volanyuk P. M.
Published: January 2023

Summary. The aim of the study. To study the pathomorphological changes in adhesion formation, and to determine the main critical moments of adhesiogenesis in adhesion disease due to acute inflammatory injuty to the peritoneum.

Materials and methods. The study included 28 cases of adhesion formation in operated patients (average age — 27.91±4.61 yrs). The material was collected intraoperatively in accordance with standard requirements for the production of histological preparations. To obtain differentiated polychromy of tissues, staining of micropreparations with hematoxylin-eosin and the van Gieson method were used.

Results and their discussion. The histological picture varied from immature granulation tissue to signs of degenerative changes in the tissue of the formed adhesions. In some cases, the development of the adhesion process acquired features of combined fibrous and fatty degeneration. The obtained data showed a clear phasic development of adhesiogenesis from the inflammatory process to the formation of powerful connective tissue structures with the phenomena of hyalinosis and secondary degenerative changes.

Conclusions. The study of the patterns of formation of the adhesion process showed that adhesion disease is characterized by a certain phasic development of changes from alternative damage and non-specific inflammation to the formation of sufficiently differentiated connective tissue and changes of a secondary degenerative nature. The obtained data create prerequisites for the development of methods of influence (prevention) at each stage of the development of adhesion disease and adhesiogenesis.
JUSTIFICATION OF THE FEATURES OF ANTIBACTERIAL THERAPY IN CIVILIAN AND COMBAT TRAUMA
Authors: Duzhyi I. D. , Shymko V. V. , Kononenko M. H. , Piatykop H. I.
Published: January 2023

Summary. Traumatism around the world is taking on unmanageable proportions. Suffice it to say that every year on a global scale, several million people die from traffic accidents and industrial and domestic injuries. Some die from the actual damage, and most die from purulent-inflammatory complications.

The urgency of the problem. Treatment of inflammatory complications requires significant funds for antibacterial drugs, but their more considerable amount is insufficient given the resistance of the microflora.

Aim. To substantiate the expediency of antibacterial therapy and methods of its application.

Materials and methods. Several experimental studies were conducted on rabbits to reveal the inhibitory effect of antibacterial drugs that enter the internal organs with various administration methods.

Results and their discussion. It turned out that after intramuscular administration, ceftriaxone accumulates in the organs of the abdominal cavity in an insufficient amount to inhibit the growth of microflora. After intravenous administration, ceftriaxone gets in the appendix in 60 % of the control after 1 hour, and after 2 hours, it decreases to 30 %, which is not very effective. After lymphotropic administration, the antibiotic accumulates after 1 hour in an amount sufficient for antibacterial action (70 %) and after 2 hours — in 95 %, which is evidence of the targeting and accumulation of antibiotics with such administration of the drug.

Conclusions. Taking into account the significant disruption of microcirculation in the impression zone, the «mileage» of the vascular bed, the aggregation of formed blood elements in microvessels, and the formation of microthrombi, the intravenous method of drug administration in traumatic disease cannot be considered optimal. This need is met by the lymphotropic way of delivering antibiotics to various organs of the abdominal and thoracic cavities.
ERGOTHERAPY AND REHABILITATION OF PATIENTS WITH COLOSTOMES AS A FACTOR AFFECTING THE QUALITY OF LIFE
Authors: Lupaltsov V. I.
Published: January 2023

Summary. The analysis of medical rehabilitation of patients with colonic stoma was carried out, the ultimate goal of which is to improve their quality of life. The relevance of these events is evidenced by the creation in many countries of public associations of stoma patients, the opening of societies for the care of patients with colonic stoma. In the USA, specialized medical schools for the training of stoma-therapists are even being created. Medical rehabilitation should become the main component of the comprehensive rehabilitation of stoma patients with financial support from the state.
DIFFERENT ANATOMY OF EXTRAHEPATIC BILE DUCT IN PATIENTS WITH CALCULOUS CHOLECYSTITIS: CLINICAL OBSERVATIONS
Authors: Vansovich V. Ye. , Kotik Yu. M. , Pshenichnyi V. I. , Vastyanov R. S.
Published: January 2023

Summary. The aim of investigation – to get acquainted with the possibilities of variant anatomy of the extrahepatic bile ducts location.

Results and their discussion. In our own practice, we observed two patients with the extrahepatic bile ducts atypical anatomy.

Patient G. was operated because of chronic calculous cholecystitis. During laparoscopic cholecystectomy, we encountered the following situation: it was found that the gallbladder has a very short duct directly in the region of the portal of the liver. After dissection it was found that d. cysticus flows into the right hepatic duct. Timely establishment of this variant anatomy, which was achieved by careful dissection of the junction area d. cysticus and d. hepaticus dexter, allowed to prevent (in this case) wrong clipping of the right hepatic duct. In this example the possibility of timely establishing the presence of anatomical features of the extrahepatic bile ducts made it possible to prevent their damage.

Patient K. was operated because of calculous cholecystitis, choledocholithiasis (without clinical and laboratory signs of mechanical jaundice). During laparoscopic cholecystectomy, it was established that the patient has variant anatomy of the extrahepatic bile ducts, when the right hepatic duct drains directly into the gallbladder. This anomaly was discovered after the separation of the gallbladder from its bed, as a result of which this duct was damaged. The access conversion was performed, the place of exit from the liver in the area of the gallbladder of the anomalous right hepatic duct was established. In order to restore the outflow of bile, a right-sided hepaticojejunostomy was performed on a Roux loop, external drainage of the choledoch according to Ker, drainage of the abdominal cavity.

Conclusions. Although laparoscopic cholecystectomy is a standard routine operation, the variability of extrahepatic bile duct location should be considered.

We consider it expedient during dissection in the area of the transition of the vesical duct to the hepaticocholedoch to carefully isolate all anatomical structures until their absolute identification.
Obstetric outcome after uterus transplantation
Authors:   University of Gothenburg, Brännström Mats , Carlsson Ylva , Hagberg Henrik
Published: January 2023

Review question / Objective: Is delivery by elective cesarean section as safe for the mother and the neonate after uterus transplantation as after delivery by elective cesarean section for reasons such as breech and psychological indication regarding stillbirth/neonatal mortality, neonatal morbidity, maternal mortality, and morbidity? Rationale: To compare pregnancy, obstetrical and neonatal complications at delivery by cesarean section in patients that have undergone uterus transplantation and in a normal groups of women.
Systematic Review on Digital Literacy Predictors
Authors:   Lusofona University, Farias Ana Rita , Sôro Jerónimo , Cabral Joana , Pereira da Costa Leonor , Ferreira Maria José , Loureiro Ana , Hugo Vitor
Published: January 2023

Review question / Objective: What are the predictors of digital literacy in the general population? Condition being studied: This review's objective is to pinpoint and assess the factors that predict digital literacy in the general public. Eligibility criteria: Primary, correlational or experimental studies with a focus on digital literacy, published in English.
Transcranial Magnetic Stimulation for the treatment of Gambling Disorder: a systematic review
Authors:   University of Catania, Concerto Carmen , Signorelli Maria Salvina , Natale Antimo , Di Francesco Antonio , Chiarenza Cecilia , Torrisi Giulia , Ciancio Alessia , Mineo Ludovico , Aguglia Andrea , Rodolico Alessandro , Lanza Giuseppe , Battaglia Fortunato
Published: January 2023

Review question / Objective: What is the effect of Transcranial Magnetic Stimulation on Gambling Disorder? Condition being studied: Gambling Disorder. Eligibility criteria: Inclusion criteria: studies evaluating the use of Transcranial Magnetic Stimulation for the treatment of Gambling Disorder including randomized and non-randomized studies; studies written in English; studies exploring an adult population, over the age of 18. Esclusion criteria: patients with other psychiatric disoders.
Obesity, adipokines and their relationship with insulin resistance
Authors: García-Ortega Wendy A. , Angulo-Camacho José Ángel , Ibarra-Sánchez Alfredo
Published: January 2023

Obesity is one of the main health problems worldwide. It is a disease that is associated with excessive food consumption, although it is also associated with a process of chronic inflammation and with a group of disorders known as metabolic syndrome. Some of the most distinctive characteristics of obesity are that the individual's adipocytes are hypertrophied, have an irregular adipokine secretion profile, have increased recruitment of inflammatory cells, and altered metabolic homeostasis; which eventually results in the development of various important pathologies or conditions, such as insulin resistance and mitochondrial dysfunction. This review aims to present the current knowledge on inflammation of adipose tissue associated with obesity.