bluuebunny/crossref_metadata_2025 huggingface dataset:
LEVEL OF P-SELECTIN AND INTEGRIN-Β3 IN BLOOD PLASMA OF PATIENTS WITH STENOTIC ATHEROSCLEROSIS OF CORONARY ARTERIES
Authors:   Addis Ababa Silk Road General Hospital, A. Chernyak , V. A. Snezhitskiy ,   Grodno State Medical University, A. V. Yanushka ,   Grodno Regional Clinical Cardiology Center, V. R. Shulika ,   Grodno State Medical University
Published: January 2025

Introduction. The problem of stenotic atherosclerosis remains one of the leading causes of morbidity and mortality worldwide, significantly impacting healthcare systems and patient quality of life. This disease is characterized by the accumulation of atheromatous plaques in the arterial walls, leading to their narrowing and eventual obstruction of blood flow. Major risk factors include hyperlipidemia, hypertension, diabetes mellitus, and smoking. The pathogenesis of atherosclerosis is multifactorial, involving complex interactions between lipid metabolism, inflammatory processes, endothelial dysfunction, and genetic predispositions. Diagnosis and treatment of atherosclerosis include both non-invasive imaging techniques and invasive procedures such as percutaneous coronary intervention (PCI). Personalized medicine and new biomarkers play a crucial role in improving treatment outcomes. Aim of the Study. To determine the levels of biochemical markers (P-selectin and integrin-β3) in the plasma of patients with ischemic heart disease (IHD) who underwent PCI, in order to assess their potential as predictors of the development of coronary artery stenosing atherosclerosis. Materials and Methods. The study was conducted at the Grodno Regional Clinical Cardiology Center from 2017 to 2023. The study included 209 patients, divided into three groups: – Group 1 (n = 31) – healthy individuals. – Group 2 (n = 30) – patients with chronic ischemic heart disease without indications for invasive coronary angiography (CAG). – Group 3 (n = 148) – patients with ischemic heart disease who underwent invasive coronary angiography and percutaneous coronary intervention (PCI). Plasma levels of P-selectin and integrin-β3 were measured using enzyme-linked immunosorbent assay (ELISA). Statistical data analysis was performed using the STATISTICA 10.0 software package.Results. Key clinical and anamnestic data showed significant differences between patient groups in terms of age, body mass index, blood pressure, and the presence of comorbidities. Levels of integrin-β3 and P-selectin were significantly higher in Group 3 compared to Group 2 and Group 1, respectively. This indicates higher inflammatory activity in patients with clinically significant stenotic atherosclerosis. Conclusions. Our study revealed differences in the clinical and anamnestic characteristics and the levels of integrin-β3 and P-selectin markers between groups of patients who developed clinically significant coronary artery atherosclerosis and those who, due to stenotic atherosclerosis, underwent PCI.
Hemispheric asymmetry in recent stratospheric age of air changes
Authors: Dubé Kimberlee , Tegtmeier Susann , Ploeger Felix , Walker Kaley A.
Published: January 2025

Abstract. Many stratospheric trace gases, including O3, HCl, and NOy, have had opposing trends in the Southern Hemisphere (SH) compared to the Northern Hemisphere (NH) during the last 2 decades. Some of this difference is due to hemispherically asymmetric changes in the rate of transport by the Brewer–Dobson circulation (BDC), and some is due to ozone depletion and recovery. The mean age of air (AoA) is a common proxy for the transport rate by the BDC in models; however it cannot be directly measured. We use observations from the Atmospheric Chemistry Experiment Fourier transform spectrometer (ACE-FTS) along with results from the Chemical Lagrangian Model of the Stratosphere (CLaMS) to derive AoA anomalies and AoA trends. The AoA is derived using observations of N2O, CH4, and CFC-12, all long-lived trace gases with tropospheric sources. We also consider CLaMS simulations driven with four different reanalyses (ERA5, ERA-Interim, JRA-55, MERRA-2). We find that, irrespective of which trace gas or reanalysis is used, air in the NH aged by up to 0.3 years per decade relative to the SH over 2004–2017. The maximum hemispheric difference in aging occurs in the middle stratosphere, near 30 hPa (∼ 24 km). We also show that the aging rate in the NH becomes smaller when the analysis is extended to 2021. The observed aging in the NH middle stratosphere contradicts model predictions of a decrease in stratospheric AoA in response to rising atmospheric greenhouse gas levels. However, the smaller aging rate during 2004–2021 compared to 2004–2017 provides some evidence that the NH aging is impacted by decadal variability and the limited length of the observation period.
The Implementation of Deep Learning Method for Disease Detection in Tomato Plants Based on Leaf Images via Web
Authors: Rachmadi Chaeru
Published: January 2025

Agriculture plays a vital role in supporting the economy. Optimally and wisely managed agricultural development can encourage sustainable economic growth and equity. One example is tomato production, which has great potential to be developed. In 2021, the production of tomatoes in all Indonesian provinces reached a total of 1,114,401 tons. However, tomato production often decreases due to disease attacks on plants. Therefore, this research aimed to identify plant diseases by utilizing deep learning methods applied to web applications, so that they can be easily accessed by farmers. Its use only requires uploading images of plants to be identified into the web application. Based on the results of training and testing conducted at Google Collaboratory using two model architectures, the findings highlight that VGG16 and DenseNet121, the DenseNet121 architecture provides higher accuracy reaching 100%, while VGG16 reaches 98.58%. In addition, in web application implementation and testing with primary data, the DenseNet121 model also showed high accuracy of 92%.
THE CULTURAL WAR IN ECONOMIC SCIENCE
Authors: Huerta de Soto Jesús
Published: January 2025

The cultural war in economic science is a conflict that revolves around the fundamental principles of liberty, free markets, and the role of the state. Economic science, primarily advanced by the Austrian School, reveals that human society, when left free from state coercion, spontaneously organizes itself into a prosperous, voluntary order. The Austrian School’s theory challenges various pseudoscientific schools that defend the state’s necessity, such as positivism, neoclassical economics, Keynesianism, and Marxism. These schools of thought, though differing in their specifics, share a common agenda: justifying coercive state intervention in the economy. The war for economic freedom requires a comprehensive intellectual strategy, one that dismantles the pseudoscientific foundations of statism and promotes the libertarian ideals encapsulated in anarcho-capitalism. The paper argues that only through the full implementation of a free market system can humanity unlock its potential for unprecedented prosperity and social harmony, moving away from the inefficiencies and violence inherent in state intervention.
PENGGUNAAN ARTIFICIAL INTELLIGENCE (AI) DALAM PEMBELAJARAN PENDIDIKAN AGAMA ISLAM: MANFAAT DAN TANTANGAN
Authors: Muchlis Muchlis
Published: January 2025

Seiring dengan perubahan dan perkembangan zaman serta semakin pesatnya globalisasi disegala bidang kehidupan, maka seluruh sektor masyarakat harus mampu bertransformasi menuju digitalisasi disegala aspek, salah satunya adalah duni pendidikan. Di antara hasil perkembangan teknologi yang semakin canggih adalah hadirnya artificial intelligence. Kecerdasan buatan (AI) telah membawa perubahan besar dalam banyak aspek kehidupan manusia. Pendidikan Islam sebagai salah satu bidang yang terkena dampak juga mengalami perubahan signifikan dalam hal metode pengajaran dan pembelajaran. Artikel ini bertujuan untuk mengeksplorasi bagaimana manfaat dan tantangan penggunaan artificial intelligence dalam pendidikan Islam dan bagaimana hal ini berpengaruh dalam proses pembelajaran di institusi pendidikan Islam.
IMPLEMENTASI PEMBELAJARAN PKN DALAM MENANAMKAN NILAI-NILAI KARAKTER BERBASIS KEARIFAN LOKAL BUDAYA BIMA
Authors: Wahyuningsih Nurul , Mahmudah Husnatul , Kusumawati Yayuk , Maulana Ikhsan
Published: January 2025

Pendidikan Pancasila merupakan aspek penting dalam pembentukan karakter dan nilai-nilai yang kuat dalam diri individu. Salah satu pendekatan yang efektif dalam mengintegrasikan nilai-nilai karakter ke dalam pembelajaran Pancasila adalah dengan memanfaatkan kearifan lokal budaya. Sebagai kearifan lokal yang kaya, budaya Bima memiliki nilai-nilai yang relevan dan dapat menjadi sumber inspirasi untuk pembentukan karakter. Penelitian ini bertujuan untuk menjelaskan implementasi pembelajaran Pendidikan Pancasila dengan memanfaatkan kearifan lokal budaya Bima dalam menanamkan nilai-nilai karakter. Pendekatan yang digunakan dalam penelitian ini adalah studi literatur dan analisis konten. Berdasarkan penelitian ini, ditemukan bahwa pendekatan yang mengintegrasikan pembelajaran Pancasila dengan kearifan lokal budaya Bima dapat secara efektif meningkatkan pemahaman dan penerapan nilai-nilai karakter pada siswa. Hasil penelitian menunjukkan bahwa implementasi pembelajaran Pendidikan Pancasila dengan pendekatan kearifan lokal budaya Bima memungkinkan siswa untuk menginternalisasi nilai-nilai seperti gotong royong, kejujuran, tanggung jawab, rasa menghargai, dan toleransi. Melalui kegiatan pembelajaran, pembiasaan-pembasaan dan  nilai-nilai yang karakter yang terdapat pada   budaya Bima, siswa dapat memahami dan mengaplikasikan nilai-nilai tersebut dalam kehidupan sehari-hari.
KREATIVITAS GURU DALAM MENANAMKAN SIKAP DISIPLIN MELALUI MANAJEMEN KELAS
Authors: Mulyadi Wahyu , Maulana Ikhsan
Published: January 2025

Dewasa ini, permasalahan kehidupan manusia mengalami perubahan yang sangat pesat. Segala macam penyimpangan-penyimpangan terjadi dalam kehidupan manusia yang disebabkan dari berbagai faktor. Penanaman sikap disiplin sangat diperlukan serta diprioritaskan dalam proses belajar mengajar dilingkungan sekolah terutama pada jenjang kelas bawah (SD/MI). Berangkat dari persoalan ini SDN 3 Kore Sanggar mengambil langkah dalam meminimalisir persoalan yang timbul dengan menanamkan serta membina sikap disiplin dalam diri siswa melalui Manajemen kelas. Jenis penelitian yang digunakan adalah penelitian kualitatif. Teknik pengambilan data melalui observasi, wawancara, dan dokumentasi. Setelah melakukan penelitian, peneliti menemukan beberapa bentuk peranan guru dalam menanamkan sikap disiplin melalui manajemen kelas yaitu; memberikan arahan, menjadi motivator, menjadi model atau panutan serta mengelola kelas, memberikan aturan pada kelas IV melalui manajemen kelas. Terlepas bentuk peranan, ada beberapa faktor yang menghambat penanaman sikap disiplin seperti kecenderungan bersikap masabodoh, pergaulan, perilaku dan keterlambatan siswa masuk sekolah. Berdasarkan faktor demikian tentu ada bentuk penguatan dalam menanamkan sikap disiplin yaitu; penguatan motivasi, pendekatan sosio- emosional, pendekatan melalui hukuman dan kerjasama guru.
Normal Gelişim Gösteren Çocukların Özel Gereksinimli Kardeşlerine Yönelik Davranışları ve Ebeveynlerin Çocuk Yetiştirme Tutumları
Authors: Laloğlu Şeyma , Karakurt Nurgül
Published: January 2025

Amaç: Araştırmada normal gelişim gösteren çocukların özel gereksinimli kardeşlerine yönelik davranışları ile ebeveynlerin çocuk yetiştirme tutumları arasındaki ilişki incelenecektir.
Yöntem: Araştırmanın evrenini, A ilinde Milli Eğitim Müdürlüğü’ ne bağlı Özel Eğitim Rehabilitasyon Merkezinde yer alan özel gereksinimli çocukların ebeveynlerinden ve normal gelişim gösteren kardeşlerinden (1073) oluşmaktadır. Araştırmada herhangi bir örnekleme seçme yöntemine gidilmeden çalışmaya gönüllü olarak katılmayı kabul eden 304 normal gelişim gösteren çocuk ve ebeveynleri araştırmanın örneklemini oluşturmuştur. Sosyo demografik Veri Formu, Aile Hayatı ve Çocuk Yetiştirme Tutum Ölçeği, Schaeffer Kardeş Davranışı Değerlendirme Ölçeği kullanılmıştır.
Bulgular: Çalışma bulguları incelendiğinde; “Aşırı Annelik Boyutu” ile “Birliktelik İlgili Olma Boyutu” ve “Empati Boyutu” arasındaki korelasyon değerleri p
Premenstrual Syndrome: Non-pharmacological Management and Recommendations
Authors: Sezer Yıldız Merve , Çağan Özlem
Published: January 2025

Premenstrual Syndrome (PMS) is characterized by physical, behavioral, and psychological symptoms that manifest during the premenstrual phase. Symptoms include irritability, mood swings, anxiety, depression, fatigue, sleep disturbances, difficulty concentrating, bloating, and headaches. PMS symptoms can adversely affect women's daily activities and disrupt their social relationships. In students, it can lead to a decline in academic performance. In Turkey, the prevalence of PMS is 52.2%, and globally, approximately one in every two women is affected by PMS. While the exact etiology of PMS remains unclear, hormonal and neurotransmitter interactions are believed to play a role. Factors such as educational level, socioeconomic status, dietary habits, stress levels, and family history of PMS may contribute to its development. Although there is no specific blood test for diagnosing PMS, diagnosis can be made by monitoring symptoms and assessing their adherence to specific criteria. Non-pharmacological management of PMS includes lifestyle modifications, traditional and complementary medicine practices, psychotherapy, support systems, and patient education. This review aims to enhance awareness among healthcare professionals regarding non-pharmacological management and recommendations for PMS, aiming to develop effective intervention strategies.
Respiratory Functions, Physical Activity and Quality of Life in A Child with Iron Deficiency Anaemia: An Evaluation-Case Report
Authors: Gökçek Özden , Çam Yağmur , Başer Miray , El Çiğdem
Published: January 2025

Childhood iron deficiency anemia (IDA) is one of the most common disorders worldwide, causing fatigue and respiratory distress. These negative symptoms of childhood IDA significantly affect the quality of life (QoL). This case report aims to evaluate pulmonary function, physical activity, and QoL in IDA. A 13-year-old girl diagnosed with childhood IDA ten years ago was admitted to the hospital. The patient's demographic information and hemogram values were recorded. Respiratory function tests (PFTs), respiratory muscle strength (RMS), and a 6-minute walk test (6MWT) were performed. Physical activity and QoL were assessed with the Children's Leisure Activities Study Questionnaire (CLASS) and Pediatric Quality of Life InventoryTM (PedsQL) 4.0, respectively. The patient's PFTs, RMS, and 6 MWT values were lower than expected. Additionally, the patient's QoL was negatively affected. This case report suggests that patients with childhood IDA should undergo physiotherapy evaluation in addition to medical treatment and be included in pulmonary rehabilitation programs.
Identification of Actionable Insights from Online Data Sources by using the Hashed Coherence Frequency Calculator (HCFC) Algorithm
Authors: B. Srinivasan
Published: January 2025

The present contemporary world is propelled by data. Everyone in society makes decisions based on the existing data and proceeds accordingly. Furthermore, all machinery is automated using advanced technologies such as Artificial Intelligence (AI), Internet of Things (IoT), Machine Learning (ML), and Data Science (DL), which predominantly harness data-driven insights for daily operations. Business organizations, social media, healthcare, big data analytics, and locality mapping are just a few modern industries that rely heavily on data-driven strategies. These areas utilize Cloud Computing (CC) to store the data in the cloud and allow access to data on any device. The primary consideration in data-driven terminology is that not all available data is utilized for decision-making. Hence, before adopting a data-driven process, it is essential to identify a collection of trustworthy and actionable insights that will enable better decision-making. This paper proposes a novel algorithm, the Hashed Coherence Frequency Calculator (HCF), for segregating actionable and non-actionable insights from the given dataset and enabling better decision-making. The algorithm is applied over two case studies containing Amazon product reviews and Google Play Store Apps review datasets.  The coherent frequency count statistical measure is mainly applied to identify actionable insights, and the outcomes will also be compared with the existing approaches.
Reversed Degree-Based Topological Indices of Alkane Line Graphs
Authors: Divya L
Published: January 2025

This paper investigates the topological indices based on reversed degree of the alkane line graph. The least reactive and most basic hydrocarbons found in organic compounds are alkanes, which are made up only of carbon and hydrogen atoms and lack any additional functional groups. In this work, the topological indices listed below were computed, specifically, the Reverse Randic index  , Reverse atom bond connectivity index  , Reverse geometric arithmetic index  , Reverse first and Reverse second Zagreb indices  , Reverse first and Reverse second Zagreb co-indices  ,Reverse hyper Zagreb index  , Reverse forgotten index  , Reverse Balaban index  ,Reverse first multiplicative-Zagreb indices  , Reverse second multiplicative-Zagreb index   and Reverse redefined first, second, and third Zagreb indices  for the alkane line graph   . The comparison of the topological indices has also been shown graphically. The results show that the Zagreb index with reverse first multiple has the highest value. It is demonstrated that the reverse first multiple Zagreb index has the best prediction performance among all the computed molecular descriptors. Additionally, a numerical and graphical comparison of these topological indices is included in this investigation.
transformación de la experiencia urbana a través del marketing inmobiliario de la ciudad de Medellín, Colombia
Authors: Menéndez García Deva
Published: January 2025

La presente investigación exploró cómo el marketing inmobiliario, mediante el uso de productos visuales como simulaciones 3D e imágenes, ha reconfigurado la dimensión socio-afectiva y la percepción urbana en Medellín, Colombia. A través de una metodología mixta, este estudio profundizó en el análisis visual y estético de imágenes provenientes de cinco portales inmobiliarios, evaluando procedencia, temáticas, estéticas e ideas subyacentes. Los hallazgos revelaron un predominio de representaciones visuales genéricas y descontextualizadas, junto con modelos 3D poco realistas que minimizan la importancia de la arquitectura en favor de la promoción estilos de vida aspiracionales. Estas estrategias de marketing optaron por una simplificación conflictiva del concepto de vida urbana, oscilando entre lo tradicional y lo global, reflejando una tensión entre la identidad local y las aspiraciones mundiales. Este fenómeno sugirió una transformación profunda de la interacción entre los individuos y el espacio urbano, mediada por narrativas visuales que enfatizaron un ideal de vida distanciado de la realidad arquitectónica y social de Medellín. La investigación concluyó afirmando que estas prácticas de marketing no solo delinean preferencias de consumo; también indican cambios en la estructura social y el tejido urbano, moldeando la experiencia y la identidad de la capital antioqueña en el contexto neoliberal.
xto neoliberal.
Hubungan biaya produksi, harga jual dan etos kerja islam dengan pendapatan petani padi dengan daya produksi sebagai variabel mediasi
Authors: Fathi Faiz Aslahul , Iskandar Iskandar
Published: January 2025

This study aimed to determine the Effect of Production Costs, Selling Prices, and Islamic Work Ethics on Farmers’ Income with Production Capacity as a Mediating Variable. This study is quantitative; the object of this study is rice farmers in Ngambakrejo Village. The population is farmers in Ngambakrejo Village; the sample taken is 83 people. Data collection was carried out by distributing questionnaires. The study results indicate that income is influenced by selling prices and Islamic work ethics, Islamic work ethics influence production capacity, production capacity affects income, and only Islamic work ethics influence income through production capacity.
Kerja jarak jauh dan produktivitas karyawan: Mengevaluasi dampak jangka panjang dari telecommuting pasca Covid-19
Authors: Sumarno Sumarno , Karsim Karsim , Dwiyanto Dwiyanto , Ekobelawati Fransiska , Christian Ferdinandus
Published: January 2025

This study evaluates the long-term impact of telecommuting post-COVID-19 on employee productivity. With the increased adoption of telecommuting during the pandemic, companies worldwide have transformed work models, necessitating an assessment of this approach’s sustainability. The study employs a literature review method, analyzing 74 articles published between 2020-2024. The study focuses on understanding the influence of telecommuting on productivity, employee well-being, and performance management strategies. The findings reveal that telecommuting offers benefits such as flexible working hours, improved work-life balance, and enhanced efficiency, particularly with adequate technological support. However, challenges such as limited communication, social isolation, and technostress pose significant barriers. To maximize the advantages of telecommuting, organizations need to provide proper technological infrastructure, training, and effective communication policies. A hybrid work model is recommended as a more flexible and inclusive approach to boost productivity while maintaining employee well-being. Telecommuting has the potential to become an integral part of modern, sustainable work strategies if managed with appropriate and adaptive policies that address employees’ needs.
Inovasi entrepreneurship business model canvas dalam membangun ekonomi berkelanjutan
Authors: Sukendri Nengah
Published: January 2025

This research aims to analyze the Entrepreneurship Business Model Canvas innovation in building a sustainable economy in the Hampers business in Mataram City. The method in this research uses a qualitative approach using literature review methods and non-participant observation. Data analysis techniques are carried out by carrying out data reduction, data presentation, inference and data verification. The Business Model Canvas is a strategic tool in an effort to build a holistic sustainable economy that allows an organization to map, analyze and redesign business models by considering sustainability aspects comprehensively. The BMC strategy with nine important elements, namely Customer Segments, Value Proposition, Channels, Customer Relationship, Revenue Streams, Key Resources, Key Activities, Key Partnership, Cost Structure can help identify opportunities to increase resource efficiency, reduce environmental impacts, and be able to create value social. BMC can not only improve a company's individual competitiveness, but can also contribute to broader changes towards a sustainable economy. Therefore, the BMC concept is an important instrument for aligning business goals with environmental and social needs in shaping a more responsible and regenerative future economic landscape.
Masa depan dimulai hari ini: Membangun kebiasaan positif pada anak TK
Authors: Katili Kevin , Godwin Danniel Tristano L. , Pertiwi Dewi , Rahardjo Richie Farandy
Published: January 2025

This community service aims to introduce the concept of diligence and laziness to students of Bethel Sulung 3 Kindergarten, Surabaya, through an interactive approach designed to attract attention and facilitate student understanding. The methods include guessing games, education with puppet stages, coloring activities, and spelling and reading simple sentences. The guessing game involves classifying daily activities based on the concept of diligent and lazy, accompanied by explanations and collecting points as motivation. The puppet stage shows animal stories about diligence and laziness. Continued with a question and answer session to strengthen student understanding. Coloring activities using characters from the puppet storyline, ants and bees, to hone creativity and instill the value of hard work. Simple literacy, introducing new vocabulary about diligence and laziness, spelling exercises, and student reading. The data was obtained from observations and analysis of children’s work results, such as the number of points received and the quality of students’ coloring. Using methods in this interactive learning has proven effective in improving students’ understanding of the concept of diligent and lazy and motivating kindergarten students to participate in activities actively.
Peningkatan pemasaran produk turunan peternakan dan pertanian melalui pemanfaatan marketplace digital di Desa Mundu Kabupaten Klaten
Authors: Susilawati Sukma Ayu , Oftasari Yosi , Salsabila Fina , Andriyani Nur
Published: January 2025

Developing rural economies that focus on village independence through small and medium-sized enterprises (SMEs) entrepreneurship provides significant benefits for the community and local government. By improving access to production resources, technology, and capital, it is hoped that the production and productivity of the community will increase, along with the realization of welfare through product sales and the creation of new jobs in the agrotourism, handicrafts, and tourism sectors. Mundu Village, Tulung District, Klaten Regency, has entrepreneurial potential from livestock and agricultural products. However, low digital literacy among business actors poses a major challenge. This community service aims to enhance digital literacy through training and assistance in creating WhatsApp Business, TikTok, and Instagram accounts. The methods of socialization and training are expected to encourage improved product marketing, ultimately enhancing the welfare of the village community. Program results indicate a 40% increase in understanding of social media marketing, a 32.4% increase in the use of digital marketplaces, and a 13.4% increase in WhatsApp Business. With support from digital technology, local products from Mundu Village are expected to compete in a broader market.
Edukasi diabetes pada remaja sebagai upaya pemeliharaan kesehatan remaja
Authors: Halimatushadyah Ernie , Lukitasari Nurraya , Yuliana Agnes , Putri Dinda Widia Aprilina , Suharto Muhammad Aldila
Published: January 2025

Diabetes mellitus (DM) is a chronic disease caused by the inability of the body to produce sufficient insulin or to use insulin effectively. The prevalence of diabetes among young people in Indonesia, based on doctor diagnoses, remained unchanged from 2013 to 2018 (0.5%). However, the percentage of young diabetes patients who do not receive treatment is 18.5% (highest). Young adults also represent the age group with the highest percentage of individuals who have never had their blood sugar levels checked (86.6%). This activity aims to provide adolescents with basic knowledge about the definition of diabetes, available therapies for young diabetes patients, and preventive measures. The method used in this community service activity involved delivering material in person and distributing brochures on diabetes prevention among adolescents at SMK Bhumi Husada. The target participants were adolescents aged 17–19 years. The activity proceeded smoothly, and the students comprehended the educational material provided. Adolescents gained an understanding of diabetes prevention, leading to healthier lifestyle behaviors.
Factores de riesgo asociados al síndrome de burnout en docentes de la provincia del Carchi
Authors: Velasco-Benavides Juan , Herrera Erick
Published: January 2025

Resumen. El síndrome de burnout es ampliamente conocido como un motivo de problema laboral que aqueja al personal docente a nivel mundial. Este problema relacionado con factores de riesgo que generan estrés surge debido al entorno laboral y diversas situaciones ligadas al trato con personas que demandan un alto nivel de dedicación e involucramiento. El presente estudio se centró en identificar factores de riesgo asociados al síndrome de burnout en docentes de la provincia del Carchi. El objetivo principal fue validar la adaptación del Inventario de Burnout de Maslach (MBI) al contexto educativo específico, y proponer un modelo de análisis de resultados basado en inteligencia artificial. Al validar el instrumento se identificó que este no se adaptaba completamente al contexto local por lo que el instrumento fue modificando, teniendo que removerse 5 preguntas que fueron identificadas como no relevantes mediante el Análisis Factorial Confirmatorio, y se incorporó información demográfica de los participantes considerada de interés para las instituciones participantes. De esta manera, para la extracción de resultados a partir del test, se diseñó un nuevo modelo de procesamiento de resultados basado en técnicas multivariantes, contemplando 37 variables de entrada. Para esto se consideraron múltiples alternativas, incluidos clasificadores binarios, redes neuronales poco profundas y cinco modelos de aprendizaje profundo, encontrando que el aprendizaje profundo, especialmente un modelo de cinco capas desarrollado con TensorFlow y Keras, ofrecía las predicciones más precisas sobre el agotamiento emocional, una dimensión clave del síndrome de burnout. Este modelo alcanzó una precisión del 86% y un MSE de 0.1193604, demostrando su fiabilidad para la detección automática del síndrome sin necesidad de diagnóstico profesional. La investigación valida la adaptación del instrumento al contexto objetivo y resalta la importancia de establecer nuevos modelos de análisis cuando se emplean instrumentos modificados a partir del MBI, asegurando su relevancia y aplicabilidad en contextos específicos.
 
Palabras Clave: Síndrome de Burnout, Factores de Riesgo, Red Neuronal Artificial
Bioactivación del quimioterapéutico ciclofosfamida mediada por citocromos P450 con fines de uso en terapia génica de cáncer
Authors: Carrera-Pacheco Saskya , Zúñiga-Miranda Johana
Published: January 2025

Esta revisión examina el papel de las enzimas del citocromo P450 en la bioactivación del agente quimioterapéutico ciclofosfamida (CPA) para uso en la terapia génica del cáncer. El estudio explora enzimas específicas del citocromo P450, como CYP2B6, CYP2C9 y CYP3A4, encargadas de metabolizar la CPA en su forma activa, destacando su potencial en la terapia del gen suicida o GDEPT. La revisión también analiza las modificaciones genéticas realizadas para mejorar la eficiencia catalítica de estas enzimas y aborda los desafíos y las direcciones futuras de la integración de GDEPT con otras terapias contra el cáncer para mejorar la especificidad y eficacia del tratamiento.
Mindfulness and Work Engagement: How Emotional Intelligence Bridges the Gap
Authors: Abaker Mostafa , Noureldin Amr , Aboueldahab Mohamed , Fakhfakh Atef , Al-Hariry Basma
Published: January 2025

This study investigates the interplay between mindfulness, emotional intelligence (EI), and work engagement, focusing on the mediating role of EI. Utilizing Conservation of Resources (COR) Theory as a theoretical framework, the research explores how mindfulness enhances employee engagement by fostering emotional regulation, resilience, and attentional stability. Conducted within the Saudi Arabian context, the study employs a cross-sectional survey of 329 employees from diverse sectors, offering culturally specific insights into these relationships. The findings reveal that mindfulness positively influences both EI and work engagement, while EI significantly mediates this relationship, amplifying the positive effects of mindfulness on engagement. These results underscore the critical role of mindfulness and EI in fostering a resilient and motivated workforce. Practical implications suggest that organizations can enhance employee well-being and productivity by integrating mindfulness and EI training into workplace development programs. This study contributes to existing literature by extending the application of COR Theory and addressing the contextual nuances of Saudi Arabia, offering actionable insights for improving employee engagement in diverse organizational settings.
Participative Leadership as a Catalyst for Digital Transformation: Building Digital Organizational Culture and Identity
Authors: Alotaibi Majad
Published: January 2025

This study explores the critical role of participative leadership in shaping digital organizational culture (DOC) and its subsequent impact on digital organizational identity (DOI), with a specific focus on the Saudi telecommunications sector and its alignment with Vision 2030. Using a quantitative research design, the study investigates the direct influence of participative leadership on DOC and DOI, as well as the mediating role of DOC in this relationship. Data were collected through a structured survey distributed to 317 employees across three major Saudi telecommunications organizations, focusing on perceptions of leadership practices, cultural integration, and digital identity. A cross-sectional approach was employed, and structural equation modeling (SEM) was used to analyze direct, indirect, and mediating relationships. Findings reveal that participative leadership fosters trust, collaboration, and inclusivity, which significantly contribute to building a robust DOC. This culture promotes technological integration, continuous learning, and innovation, aligning employee behaviors with organizational technological goals and enhancing DOI. The results also underscore the transformative potential of DOC as a mediating variable that bridges leadership strategies with organizational identity, highlighting the synergistic effects of leadership and culture in driving organizational success. By contextualizing these relationships within Saudi Arabia’s digital transformation agenda, the research provides actionable insights for leveraging leadership and culture to achieve Vision 2030 objectives, including fostering innovation, developing digital infrastructure, and enhancing competitiveness. These findings contribute to existing literature on leadership, culture, and identity in digital transformation, offering a strategic framework for organizations seeking to adapt and excel in the digital age.
Information Modeling Methodology in the Distance Learning Process
Authors: Kryshtanovych Myroslav , Noskova Margaryta , Gavrysh Iryna , Kholtobina Oleksandra , Solovyov Valeriy , Polets Mariia-Viktoriia
Published: January 2025

This article explores the development and application of an information modeling methodology in the distance learning process. The aim is to provide an integrated framework that encapsulates theoretical underpinnings, empirical insights, and practical procedures for designing, implementing, and evaluating an information model suitable for contemporary distance learning environments. In doing so, this paper draws on a broad range of literature related to digital technologies in education, socio-economic transformations, sustainable development, and security considerations. Beginning with an introduction to distance learning and the role of information modeling, the article proceeds to review significant scholarly contributions. It then outlines a comprehensive methodology centered on model design, data gathering, and validation. The results section provides insights gleaned from real-world contexts and case studies, while the discussion underscores the challenges, opportunities, and best practices for stakeholders in distance learning. Finally, the paper concludes with an emphasis on future prospects, policy recommendations, and the role of interdisciplinary collaboration. This examination stands on the foundation of multiple studies, including those addressing the development of modern socio-economic systems under global digitalization, the integration of digital technologies in education, modeling approaches in sustainable development, and strategic management considerations in times of crisis or warfare.
Enhancing Concrete Performance in Marine Environments: Insights into Seawater Effects and Cement Optimization
Authors:   Department of Civil Engineering, Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State, Nigeria., Dim Bonaventure C. , Mmonwuba Nwanneka C. ,   Department of Civil Engineering, Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State, Nigeria.
Published: January 2025

This study investigates the effects of seawater on the compressive strength of concrete through experimental analysis. Experimental cement concrete cubes of 150mm x 150mm x 150mm were cast using diﬀerent mixes of concrete mixed and cured in seawater in order to determine the compressive strength. All the mixes were prepared using various water-cement ratios (w/c) ranging from 0.5 to 0.6 by weight. A total of 60 concrete cubes were made in twenty batches; the cubes were cast and cured in sea water. The curing was done for 21days, and then crushed using the Compressive Strength Test Apparatus at the prescribed age. The study shows an increase in the compressive strength of concrete for concrete specimens mixed with seawater during the early stages of curing, up to 14 days. However, after 28 days and beyond, the compressive strength of concrete mixed and cured with seawater begins to decrease.
Margaritasita: Un mineral exclusivamente Chihuahuense
Authors: Faudoa Gómez Fabián Guadalupe , Montero Cabrera María Elena , Esparza Ponce Hilda Esperanza , Fuentes Cobas Luis Edmundo , Canche Tello Jesús Gonzalo
Published: January 2025

La margaritasita [Cs2(UO2)2(VO4)2·nH2O] es un uranovanadato descrito hasta el día de hoy únicamente en la Sierra Peña Blanca, Chihuahua. En este trabajo se comparten los resultados obtenidos de la caracterización de margaritasita, empleando las técnicas de difracción de rayos X de alta resolución (DRX-AR) y espectroscopía de estructura fina por la absorción de rayos X (EXAFS), las cuales utilizan luz sincrotrón. Para este trabajo se realizó la caracterización en el sincrotrón de Diamond Light Source estación B18 (en Reino Unido) y en el difractómetro de alta precisión de Elettra en Triestre (Italia). 
La margaritasita, con hábito tabular micrométrico entre 1 y 3 μm, presenta las fases margaritasita pura y carnotita en solución sólida desordenada con una relación de potasio (K) y cesio (Cs) de 1:1, acompañadas de cuarzo, montmorillonita, feldespato potásico y calcita. Mediante estructura de los rayos X cerca del borde de absorción (por sus siglas en inglés XANES) y EXAFS se comprobó la asociación de vanadio y cesio con uranio en la fase margaritasita. En el estudio se caracterizó la estructura del prisma pentagonal uranilo determinando las distancias de unión entre el uranio y el oxígeno U-O, característica de los uranovanadatos.
DOI: https://doi.org/10.54167/tch.v19i1.1675
Humedales construidos de flujo subsuperficial horizontal como alternativa para la remoción de metales pesados en efluentes de minería aurífera
Authors: Sierra Gaviria Edwin Fernando , Fernández Vargas Karol Daniela , Fernández Morantes César , Arias Hoyos Arnol
Published: January 2025

En la actualidad, uno de los problemas con mayor connotación que acarrea la humanidad se encuentra centralizado en la contaminación ambiental, donde la calidad del recurso hídrico, el aire y el suelo se encuentran en constante detrimento, influyendo sustancialmente en la salud pública y el bienestar y forma de vida de los individuos. Así pues, la minería aurífera artesanal desata diversos problemas de índole ambiental, principalmente a la matriz hídrica, dado que los residuos líquidos producto del beneficio de oro son vertidos al suelo y cuerpos de agua sin ningún tipo de tratamiento. De acuerdo con lo anterior, el objetivo de esta investigación es evaluar la eficiencia de un humedal construido de flujo subsuperficial horizontal en la remoción de metales pesados presentes en efluentes mineros. La ejecución del estudio consistió en tres fases, integradas por una caracterización fisicoquímica del efluente, posteriormente, el diseño y construcción del humedal a escala piloto, finalmente, la operación y seguimiento para la evaluación de la eficiencia de remoción. Se lograron detectar trazas de mercurio y plomo que no cumplen con la normativa colombiana para vertimientos (Resolución 0631 de 2015). Así mismo, se diseñó un sistema de humedales construidos que permitieron evaluar la eficiencia de dos tipos de macrófitas para la remediación ambiental del efluente.
Caso de aprendizaje para la asignatura de seguridad operacional para el programa de ciencias militares aeronáuticas de la Escuela Militar de Aviación “Marco Fidel Suárez”
Authors: Duarte Gallo Jorge Armando , García Alarcón Cristian David
Published: January 2025

Este estudio de caso tiene como objetivo estructurar una estrategia didáctica para la toma de decisiones de la Asignatura electiva “Crew Resource Management (CRM)” en la instrucción de vuelo, dentro del programa académico de Ciencias Militares Aeronáuticas, en el cual se forman los futuros pilotos de la Fuerza Aérea Colombiana FAC.
La investigación de enfoque mixto, combinando métodos cuantitativos y cualitativos. En el análisis de información se consideran manuales y otros documentos institucionales, además de experiencias de empresas nacionales e internacionales. Entre las técnicas para la recolección se utilizan entrevistas a expertos, que por su capacitación y experiencia han utilizado estos conocimientos en el FAC; se entrevistaron oficiales activos y en retiro, de la Oficina de Seguridad Operacional del Comando Aéreo de Combate No. 7, pilotos que formaban parte de grupos de combate y de entrenamiento de vuelo, y personal experto en psicología aeronáutica, con varios años de trayectoria en el campo del CRM. Los resultados de esta investigación se orientan a mejorar las comunicaciones, externas e internas, de las tripulaciones desde la Seguridad Operacional con temas de CRM para evitar la menor cantidad de accidentes posibles, logrando así vuelod seguros y eficientes.
PELATIHAN PENANAMAN TANAMAN OBAT KELUARGA (TOGA) UNTUK MENINGKATKAN PENGETAHUAN MASYARAKAT DESA PLAOSAN SIDOARJO
Authors: Wahyu Budi Pratama Muhamad Dion , Claresta Nathania Resty , Hakim Luqmanul , Khusna Asmaul , Yeyen Tua Mariana Anjali , Arditiya Rheyna Putri , Nasrullah Rachmad , Alfarisi Muhammad Salman , Safitri Avida Nurisa , Prajitno Sunyoto Hadi
Published: January 2025

Abstract: The program implemented by KKN students Family medicinal plants (TOGA) are being planted and used in an attempt to enhance family health, particularly in the food industry. program. In this program students use methods including (1) preparation, preparing what will be done and what items will be used. (2) debriefing, providing debriefing through socialization at one of the RW village halls. And (3) implementing the KKN program, planting each RW with 10 TOGA plant seeds consisting of three tomato seeds, three eggplant seeds and 4 chili seeds. The benefits and properties of TOGA that are cultivated are not yet known, therefore outreach is needed to the local community to better understand and know the benefits of the TOGA plant for our body's health, although the benefits of TOGA have been known for a long time, its use is limited to a concoction that has been prepared as a family medicine for many years. But few individuals are aware of the advantages. of the TOGA plant, therefore this outreach can help people become more familiar with the TOGA plant and its benefits for the body to maintain health. Keywords: Plants; TOGA; Plaosan Village  Abstrak: Inisiatif penanaman dan konsumsi Tanaman Obat Keluarga (TOGA) mahasiswa KKN bertujuan untuk meningkatkan kesehatan keluarga, khususnya di sektor pangan. Dalam program ini mahasiswa menggunakan metode yang dilakukan antara lain (1) persiapan, mempersiapkan apasaja yang akan dilakukan dan apasaja barang yang digunakan. (2) pembekalan, memberikan pembekalan melalui sosialisasi di salah satu balai desa RW. Dan (3) pelaksanaan program KKN, melakukan penanaman per RW dengan masing-masing terdapat 10 bibit tanaman TOGA yang terdiri dari tiga bibit tomat, tiga bibit terong dan 4 bibit cabai. Meskipun manfaat TOGA bagi kesehatan telah lama diketahui, penggunaannya terbatas pada ramuan yang dibuat sebagai obat keluarga yang diwariskan secara turun-temurun. Oleh karena itu, perlu dilakukan edukasi kepada masyarakat setempat tentang manfaat tanaman TOGA karena khasiat dan manfaatnya belum diketahui. Namun, belum banyak masyarakat yang mengetahui khasiat tanaman TOGA, oleh karena itu melalui sosialisasi ini, masyarakat akan lebih mampu memahami tanaman TOGA dan bagaimana tanaman tersebut dapat membantu menjaga kesehatan tubuh. Kata kunci: Tanaman; TOGA; Desa Plaosan
BERKEBUN DAN BUDIDAYA IKAN DI KAWASAN PERKOTAAN: APLIKASI BUDIKDAMBER SEBAGAI SOLUSI PENINGKATAN KEMANDIRIAN PANGAN UPAYA MENDUKUNG GREEN ECONOMY
Authors: Karina Indira , Ikhlas Boni , Desmiati Ira , Aisyah Siti , Munzir Abdullah
Published: January 2025

Abstract: The Lubuk Tempurung Indah Fish Farming Group mainly cultivates tilapia. Since the last 5 years, agricultural land and fish farms in Kuranji Village have been disappearing and replaced by housing complexes. This has caused production from farmers and fish farmers to decline. To overcome this problem, the solution designed is skills training on the technical aspects of BUDIKDAMBER or fish farming in a bucket with a hydroponic system at the top. Assistance in BUDIKDAMBER and hydroponic business management starting from planning, organizing, directing to supervising the products produced and assistance in product marketing through improving marketing strategies by utilizing internet networks or websites (e-commerce). The result of this activity is the emergence of new products resulting from the diversification of the application of Budikdamber science and technology, namely live stalls (vegetables and fruits) and growing TOGA (family medicinal plants) and catfish from Budikdamber. The formation of business management ranging from planning, organizing, directing to supervising the products produced. Partners are able to make well-organized financial and administrative bookkeeping, and are able to market products utilizing the internet network or website (e-commerce).Keywords: BUDIKDAMBER, Hydroponics, Marketing, Business Development. Abstrak: Kelompok Budidaya Ikan Lubuk Tempurung Indah sebagian besar hanya membudidayakan ikan nila. Sejak 5 tahun terakhir lahan pertanian dan budidaya ikan di Kelurahan Kuranji semakin menghilang dan berganti dengan komplek perumahan. Ini menyebabkan produksi dari petani dan pembudidaya ikan semakin menurun. Untuk mengatasi masalah tersebut solusi yang dirancang adalah pelatihan keterampilan pada aspek teknis BUDIKDAMBER atau budidaya ikan dalam ember dengan sistem hidroponik di bagian atasnya. Pendampingan dalam manajemen usaha BUDIKDAMBER dan hydroponic mulai dari perencanaan, pengorganisasian, pengarahan hingga pengawasan terhadap produk yang dihasilkan dan pendampingan pada pemasaran produk melalui peningkatan stategi pemasaran dengan memanfaatkan jaringan internet atau website (e-commerce). Hasil dari kegiatan ini adalah munculnya produk baru hasil diversifikasi penerapan IPTEK Budikdamber yaitu warung hidup (sayur dan buah-buahan) dan menanam TOGA (tanaman obat keluarga) serta lele hasil Budikdamber. Terbentuknya manajemen usaha mulai dari perencanaan, pengorganisasian, pengarahan hingga pengawasan terhadap produk yang dihasilkan. Mitra mampu membuat pembukuan keuangan dan administrasi yang tertata baik, dan mampu memasarkan produk memanfaatkan jaringan internet atau website (e-commerce).Kata kunci: Budikdamber, Hidroponik, Pemasaran, Pengembangan Usaha.