bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of merits of DNA sequencing, PCR-SSCP and MFP assays in the detection of drug resistance in Mycobacterium leprae
Authors: Long Fan , Li JiuLong , Jia Jiedeng
Published: March 2022

Purpose: To compare the merits of conventional Mouse Foot Pad (MFP) assay, Polymerase Chain Reaction-Single Strand Conformation Polymorphism (PCR-SSCP) analysis, and Direct-DNA sequencing in identification of drug resistance in M. leprae.

Methods: A total of 41 leprosy cases were investigated for drug resistance using MFP assay, whereby growth results were obtained in 23 cases. The DNAs extracted from these samples were amplified in polymerase chain reaction (PCR) using specific primers in order to determine the drug resistance-loci. Furthermore, PCRSSCP analysis was carried out using PCR amplicons, while gel electrophoresis was performed to identify any shift in mobility in any one of the DNA strands, as well as the pattern of mutation.

Results: A total of 5 isolates exhibited the highest degree of resistance R100, whereas 4 isolates showed intermediate level of resistance R10. In contrast, the least resistance was seen in R1. There were no mutations in 4 out of 10 strains which were dapsone-resistant, i.e., 1 HR, 2 IR and 1 LR. Moreover, there was no mutation in 305 bp sequence of the rpoB gene. DNA sequencing sensitivity was 60 %, whereas the sensitive isolates tested in the experiments exhibited no mutation, resulting in 100 % specificity.

Conclusion: These results indicate the advantages of molecular techniques over conventional MFP technique. The study has revealed that PCR-SSCP analysis, a rapid, specific and less expensive method, has greater potential for use in routine testing of the susceptibility of M. leprae to rifampicin and dapsone, than the other tests.
A Scalable Algorithm for Decentralized Actor Termination Detection
Authors: Plyukhin Dan , Agha Gul
Published: March 2022

Automatic garbage collection (GC) prevents certain kinds of bugs and reduces
programming overhead. GC techniques for sequential programs are based on
reachability analysis. However, testing reachability from a root set is
inadequate for determining whether an actor is garbage: Observe that an
unreachable actor may send a message to a reachable actor. Instead, it is
sufficient to check termination (sometimes also called quiescence): an actor is
terminated if it is not currently processing a message and cannot receive a
message in the future. Moreover, many actor frameworks provide all actors with
access to file I/O or external storage; without inspecting an actor's internal
code, it is necessary to check that the actor has terminated to ensure that it
may be garbage collected in these frameworks. Previous algorithms to detect
actor garbage require coordination mechanisms such as causal message delivery
or nonlocal monitoring of actors for mutation. Such coordination mechanisms
adversely affect concurrency and are therefore expensive in distributed
systems. We present a low-overhead deferred reference listing technique (called
DRL) for termination detection in actor systems. DRL is based on asynchronous
local snapshots and message-passing between actors. This enables a
decentralized implementation and transient network partition tolerance. The
paper provides a formal description of DRL, shows that all actors identified as
garbage have indeed terminated (safety), and that all terminated actors--under
certain reasonable assumptions--will eventually be identified (liveness).
Dosis, intervalos de aplicación y rotación de cuatro plaguicidas granulados, registrados para el control de nematodos y el picudo negro (Cosmopolites sordidus Germar) en plátano
Authors: José A. Chavarría-Carvajal  , Héber Irizarry
Published: March 2022

Se estudió la eficacia de los plaguicidas granulados aldicarb, carbofuran, etoprop y fenamifos en plátano, usando las dosis recomendadas en la etiqueta del producto y dosis e intervalos de aplicación más bajos que los recomendados. También, se probaron estos plaguicidas en rotación. Todos los compuestos fueron efectivos en reducir las poblaciones de Radopholus similis y Pratylenchus coffeae cuando se aplicaron en dosis más bajas que las recomendadas en la etiqueta y a intervalos de cuatro meses, o cuando se aplicaron en rotación Excepto por etoprop, los demás compuestos fueron efectivos en reducir el daño causado por el picudo negro, cuando se aplicaron en dosis más bajas y a intervalos más cortos que lo recomendado en la etiqueta, o en rotación. Sin embargo, los tratamientos con mayor eficacia como insecticidas fueron fenamifos y la rotación de aldicarb, fenamifos y carbofuran aplicados a la siembra y a intervalos de seis meses. Ninguno de los tratamientos afectó significativamente los componentes de rendimiento en la cosecha de plantilla.
Bioreguladores y la calidad de la planta de pascua
Authors: Gerardo Ruiz-Sifre  , Luis R. Santiago-Santos  , Lucas V. Ramírez-Ramos
Published: March 2022

Se aplicó paclobutrazol a 0, 12.5, 25 y 37.5 mg/L y uniconazole a 0, 5, 10 y 15 mg/L a las plantas de pascua 'Eckespoint Freedom Red' y 'Gross Supjibi Red', mediante aspersiones al follaje o empapando el suelo. En ambos cultivares el tamaño de las plantas de pascua se redujo significativamente cuando el suelo se empapó con cualesquiera de las tres concentraciones de paclobutrazol o uniconazole. Cuando se empapó el suelo con paclobutrazol (12.5 mg/L) o uniconazole (5 mg/L) se redujo el tamaño de la planta de pascua por un período más prolongado que cuando se asperjó el follaje. Los reguladores de crecimiento aplicados empapando el suelo causaron una reducción en el diámetro de las bracteas de ambos cultivares. El uso de reguladores de crecimiento como paclobutrazol y uniconazole en la planta de pascua puede mejorar la calidad (tamaño) de éstas en Puerto Rico.
Transforming Data for Reuse and Re-publication with XML and XSL
Authors: Beals M. H.
Published: March 2022

This tutorial will provide you with the ability to convert or transform historical data from an XML database (whether a single file or several linked documents) into a variety of different presentations—condensed tables, exhaustive lists or paragraphed narratives—and file formats.
Assessment of Flood Hazard Zonation Using Geographic Information System and Analytical Hierarchy Process: A Case Study of Tlawng River Watershed in Sairang, Mizoram, India
Authors: Malsawmtluanga . , Vabeihmo Ch.
Published: March 2022

Flood occurs when the water inundates normally dry ground, which could happen in a variety of ways like excessive rainfall, overflowing of embankments, dams, rivers, snowmelt, and other factors. Floods are one form of a natural hazard which are difficult to contain and control. A flood susceptibility mapping using Geographic Information System (GIS) and Analytical Hierarchy Process (AHP) techniques were carried out at Sairang village in Aizawl, Mizoram in Northeast India. The study area Sairang is situated on the banks of the Tlawng river, the longest river in Mizoram. Floods have wreaked havoc in Sairang frequently resulting in huge losses and damage to property with numerous loss of life over the years. The total study area is 131.27 sq km and the resulting flood hazard potential zonation map shows that 1/3 of the watershed area falls in Vey High and High Potential Flood Hazard Zonation areas.
Experimental Studies on Concrete by Replacing Natural Sand with M-Sand
Authors: Kanchikere Abdulsattar , . Madhukaran , Eramma H
Published: March 2022

As a result of the increasing usage of concrete, globalization has increased the demand for cement and sand. The cement industry is the second greatest CO2 emitter after the petroleum and oil sectors, and the civil industry is responsible for global warming due to misuse of river sand, depletion of river sand courses, and lower water levels at the surface. In this project, 0%, 25%, and 50% river sand is replaced by an M-sand, which minimizes the consumption of river sand and assists in the recovery of water levels from the surface. In this project M50, M55, and M60 grade concrete was used and compared the outcomes to normal concrete by running an experimental program for Seven and Twenty-eight days of curing period. When 50% of the manufacturing sand is replaced with natural sand, excellent strength parameters are achieved after 28 days. And it is more economical than River sand.
Efecto del riesgo de liquidez en el costo de financiamiento del sistema financiero: un análisis para el caso peruano, periodo 2015-2020
Authors: Quispe Mamani Julio Cesar , Flores Turpo Giovana Araseli , Velásquez Velásquez Wily Leopoldo , Quispe Lino Carmen Nievez , Choque Alanoca Daysy Silvia , Huarcaya Yana Edgar Rolando
Published: March 2022

La rentabilidad de las entidades financieras a través del costo de financiamiento puede verse afectada por escenarios de tensión de riesgos de liquidez, por lo que la presente investigación busca responder la pregunta ¿El riesgo de liquidez diferenciado en financiamiento jurídico, natural, en moneda extranjera y nacional tienen algún efecto sobre el costo de financiamiento de las entidades bancarias de la banca múltiple, periodo setiembre 2015-noviembre 2020?; el objetivo fue analizar el riesgo de liquidez de la banca múltiple del sistema financiero peruano a través de la volatilidad de los depósitos y estimar el efecto sobre la rentabilidad de la banca múltiple a través del costo de financiamiento, teniendo en consideración las diferencias entre financiamiento jurídico, financiamiento natural, financiamiento en moneda extranjera y en moneda nacional. El método que se aplicó es un modelo de vectores autorregresivos (VAR) y funciones impulso respuesta, además de aplicar el modelo GARCH para hallar el nivel de volatilidad de los datos. Se trabajó con datos de la Superintendencia de Banca, Seguros y AFP (SBS), utilizando el Eviews 10. Se determinó que la volatilidad de depósitos en moneda nacional explica el comportamiento del costo de financiamiento, es decir, a mayor volatilidad de depósitos en moneda nacional genera mayores costos de financiamiento, asimismo; se obtuvo que la volatilidad de depósitos de personas jurídicas, la volatilidad de depósitos de personas natural y la volatilidad de depósitos en moneda extranjera no explican el comportamiento del costo de financiamiento.
EROTISMO E IDENTIDADE
Authors: Mineiro Daniel
Published: March 2022

À sociedade atual, dizia Byung-Chul Han, falta erotismo. Estamos todos envoltos numa estética, que não nos deixa ver esta necessidade. Por isso, por meio de uma atenção fenomenológico hermenêutica, é preciso mudar o estatuto da realidade, o modo como percecionamos a realidade e apontar as consequência antropológicas desta mudança, que é erótica. Só desta forma, o homem se vê a braços com a densidade do real e ganha sentido o simbolismo erótico, que é utilizado na nova forma de espiritualidade que é o ato de tatuar a pele.
A SACRALIDADE DA SIMBÓLICA E OS NOVOS MODELOS DO SAGRADO
Authors: Mineiro Daniel , Pinto Paulo Mendes
Published: March 2022

No horizonte católico, a simbólica assume a perspetiva dos discursos apo fáticos. Toda a comunicação decorre das “provas”, mesmo que negativas, de uma figura de tipo divino. Nas espiritualidades e religiões ancestrais, é possível falar de uma vivência de uma experiência do sagrado, que é mais libertadora. Otto, Eliade, Durkheim, Hulin falaram da fruição, mas na cultura urbana atual, a cultura das tatuagens permite reconfigurar o horizonte do conceito de sagrado. Mimetizando outras culturas, os conceitos de corpo, de vivência, de poder, de desejo, de simbólica, de imaginário coletivo e de transformação do sujeito apresentam uma fenomenologia da identidade, uma recuperação do poder da simbólica e uma responsabilização do sujeito pela sua identidade, que nada tem que ver com a crença.
Storying Ways to Reflect on Power, Contestation, and Yarning Research Method Application
Authors: Murrup-Stewart Cammi , Atkinson Petah , Adams Karen
Published: March 2022

Internationally within academia settler-colonial processes occur in various ways alongside a growth in the use of research methods conceived with Indigenous knowledges. However, most research environments and practices are built upon and privilege dominant non-Indigenous settler-colonial knowledge systems. It is within this power imbalance and contested space that Yarning research method is being applied and interpreted. Underpinned by an Indigenous Research Paradigm, we employed storying ways to examine researcher experiences of settler-colonialism and the Yarning research method. The story outlines challenges and pitfalls that researchers can fall into and critically examines how researchers can fail to recognise the depth of Indigenous knowledge embedded within the practice. This story is gifted by creating an imagined narrative interview with a character called Settler-Colonisation, whereby we identify a litany of settler-colonial processes impacting Yarning research. Scrutinising the epistemological and methodological practices and processes enacted in academia is imperative for better-informed application of Indigenous research methods and create sustainable research more generally.
OTOMATISASI TEKNOLOGI SMART HOME MENGGUNAKAN ARDUINO BERBASIS INTERNET OFF THINGS (IoT)
Authors: Suhendar Benny , Fatullah Rizki
Published: March 2022

"IOT-based Interactive Monitoring and Monitoring System for home automation" is another technological advance that can control and filter gadgets or other devices to control home automation remotely. Every automation business that uses an inserted system such as a PIC microcontroller provides an intelligent, inexpensive energy protection system, for homes, schools, hospital facilities or others. The main objective of this research is to plan and provide an interesting implementation point of IoT for home applications and also other means to control or control existing equipment in the house such as turning on / off lights, fans, gas, patterns, doors and others by using sensors, which serve to control. In general, we know that we use a number of equipment in homes, theaters, shopping centers, Convention Centers, Hotels and other facilities whose equipment we connect directly to electricity and consume power. Because of this, some equipment has failed due to excess voltage. Here, we use several components to control the excess voltage. In this model we use a micro controller (ATMEGA328P), which is connected to a nodemcu, 4-channel relay board, and liquid crystal display (LCD). Here the input is given to the micro controller via the LCD to display the temperature. The output of this signal is given to the micro controller where the pin becomes active when there is a problem finding room temperature. A 4-channel relay board is connected to control large equipment, meanwhile we connect switches to operate and nodemcu (Wi-Fi module) to control with remote access.
PERANCANGAN SISTEM INFORMASI PENJUALAN BERBASIS WEB PADA BENGKEL KARUNIA BAN PAMULANG
Authors: Effendi Rustam , Efendi Yasin , Najib Ainun , Najib Ainun , Najib Ainun
Published: March 2022

The use of technology in the company not only supports business processes but also very important on corporate earning. Business ownerhave always pay attention to the development of the existing technology in order to improve their business success. Therefore many companies want to implement the technology edgein every aspect ofits business processes. Karunia Ban machine shop is a trading company that sells a wide range of tires, especially for goods and service fees. Sales transactions that occur on Karunia Ban shop are still being done manually. Companies often find it difficult to know which sales transaction that are for spare parts or for repair services, so we need an information system tosolve the problem. Information systems is expected to optimize the sales in Karunia Ban machine shop. The methodology that we used to analysis and to develop the structured system are using UML (Unified Modelling Laguage). The expected results from this paper is to establisha procedure that describes a system using UML analysis and design a system that runs the system, the draft also produced a web-based sales application using php and my sql.
EFFECT OF NaCl CONCENTRATION ON THE PRODUCTION OF Arthrospira maxima CULTIVATED IN THE HUMID TROPICS
Authors: Fernández-Corte Baruc , Hernández-Cázares Aleida Selene , Gómez-Merino Fernando Carlos , De Cangas Ramón , Rodríguez-Palacio Mónica , García-Gómez Oscar , Ríos-Corripio María Antonieta
Published: March 2022

The production of microbial biomass can be affected by the composition of the culture medium, including the content of salts and there is little information in terms of the NaCl concentration. Therefore, in this study, the effect of the addition of different NaCl concentrations (0.0, 2.0, 2.5, and 3.0 g L-1) in a Jourdan medium was evaluated on cell growth and physical and chemical properties of Arthrospira maxima cultivated in the region of Cordoba, Veracruz, Mexico. The experiment was established under a completely randomized design with a factorial arrangement (AxB). During the production stage, cell growth and morphology of filaments were evaluated, and after harvesting, the physical and chemical analysis (moisture, crude fiber, total protein and lipid content, mineral composition, photosynthetic compounds, antioxidant activity, and structural composition through FTIR-Spectroscopy analysis) of A. maxima was performed. Results obtained show that the addition of NaCl did not affect cell development, the morphology of the filaments, or the content of photosynthetic compounds. The maximum rate of biomass production in all treatments was at 6 d, without significant differences (p > 0.05) among treatments. In all treatments, A. maxima showed adequate concentrations of protein and minerals, as well as antioxidant activity. FTIR spectra showed absorption bands associated with proteins, carbohydrates, lipids, and nucleic acids. A decrease in the amide I and amide II bands of the proteins was observed with the addition of NaCl. A. maxima cultivated in these tropical climatic conditions had excellent properties to be used as a functional ingredient in the development of innovative and biotechnological food products for human consumption.
TWG Tea-Exploring the Case Study on Innovation Diffusion of Taiwan Tea
Authors: Chang Chih-Chao , Kao Fang-Chen , Chang Justine S. , Chien Charles S.
Published: March 2022

Abstract

In Taiwan the geography, climax and environment are suitable for growing tea plants. Delicate agricultural planting techniques and exquisite tea making skills have allowed Taiwan tea to stand in world arena as early as more than one hundred year ago. The whole world knows that Taiwan has very excellent and high economical value tea products like Oolong tea, Oriental Beauty tea, and Paochong tea, etc. However, until today Taiwan tea still doesn’t have international famous brand. England, France and USA don’t grow tea leaves, but they all can create world famous tea brand, of which main products are in tea bag types.
The study would look into brand constructing process of a case company, TWA Tea, to study and analyze how TWG Tea successfully broke the traditional constraint with innovation thoughts to establish new business model and lock in high consumption groups, creating a luxurious tea brand. The study would also deconstruct TWA tea model in strategic positioning, cost, organization, process flow, aesthetics, and brand, etc., thus such successful experience can reflect on Taiwan tea innovation to expand to the entire world, hoping to create golden opportunity for Taiwan tea industry once more.

Keywords: Tea bag, Strategic positioning, Brand construction, Innovation diffusion, Aesthetics.
Virovitička hrvatska nacionalna omladina između dva svjetska rata do pristupa Ustaškoj mladeži 1941.
Authors: Pilić Stipe
Published: March 2022

Rad se bavi nastankom hrvatske omladine u Virovitici 1920-ih godina, daljnjim razvojem nakon tih godina, revolucionarnim djelovanjem po uspostavi šestosiječanjske diktature i sudbinama pojedinaca kroz individualne terorističke akcije. Poslije kratkotrajnog gotovo prestanka rada omladine u zemlji, njen se rad prvo pojačava kroz djelovanje u nelegalnim poluvojnim i paravojnim postrojbama Hrvatske seljačke i građanske zaštite. Nastankom Banovine Hrvatske (BH) osniva se Hrvatski Junak, najmasovnija organizacija hrvatske nacionalne omladine od 7 do 21. godine koja je pod utjecajem i vodstvom Hrvatske seljačke stranke (HSS). Nastankom Nezavisne Države Hrvatske (NDH) Hrvatski Junak u kratkom vremenu, do rujna 1941. kompletno prilazi ustaškoj mladeži. Nova država u ustašku mladež nastoji okupiti cjelokupnu mladež od 7 do 21 godinu, što će joj administrativno i poći za rukom. U svim razdobljima omladina je predstavljala borbene dijelove stranaka ili države i najčešće bila svojevrsna paramilitarna, poluvojna organizacija.
The implications of active blended learning for English teaching in a Chinese university
Authors: Zhang Huan , Fisher Bob
Published: March 2022

Blended Learning (BL), which is usually defined as a combination of face to face (F2F) and online instruction, has attracted considerable interest in recent years and has been increasingly adopted within the higher education sector. In this research, a thematic inductive analysis was conducted to explore how the practice of Active Blended Learning (ABL) at a British university, University of Northampton (UON) might inform the BL College English teaching curriculum design at a Chinese university, Henan Normal University (HNU), so that students may enjoy a more enhanced learning experience in both online and F2F contexts. In the study, 10 teachers from different disciplines at UON and 10 College English teachers from HNU were interviewed for between 45 and 60 minutes. The findings of this study suggest that the implementation of BL in College English courses at HNU should be supported by the institution in terms of pedagogical design, policy, staff development, technical infrastructure and small class size.
Between the office and the coffee shop: an examination of spaces used for research degree supervision
Authors: Specht Doug
Published: March 2022

The last two decades have seen increased attention given to the role of space within the university campus, with numerous new learning spaces forming part of both the physical and the digital campus. Much of the focus of how these spaces work to create supportive learning environments has been on undergraduate teaching. However, these spaces offer a great opportunity to also enhance the doctoral researcher’s supervision process through the creation of new learning spaces that break away from the traditional office setting. In taking the coffee shop as the antithesis of the office, this paper examines theories around space-making in relation to doctoral research, adding in the experiences of UK doctoral researchers to provoke further thought and discussion about how new spaces within a university and outside the campus might be considered part of the pedagogical approach to supervision. Results suggest that although there is much to be considered, doctoral researchers spend the majority of their time in traditional spaces—where they feel the most comfortable—and become progressively less comfortable the further supervision moves towards public spaces.
Keputusan Pembelian Produk Garnier Ditinjau Dari Kualitas Produk, Citra Merek dan Harga (Studi Kasus Mahasiswa Universitas Islam Batik Surakarta)
Authors: Tanjung Sari Nikmah Ayu , Kustiyah Eny , Istiqomah Istiqomah
Published: March 2022

Abstrak. Tujuan penelitian guna melihat pengaruh variabel kualitas produk, citra merek dan harga terhadap keputusan pembelian produk Garnier di Universitas Islam Batik Surakarta secara simultan serta parsial. Deskriptif ialah jenis dari penelitian ini mempergunakan metode kuantitatif. Mengumpulkan data lewat studi kepustakaan serta kuesioner. Instrumen pada penelitian ini penyebaran kuesioner kepada 100 responden konsumen produk Garnier yang ditentukan mempergunakan teknik Purposive Sampling. Peneliti mempergunakan analisis uji regresi linier beranda. Uji tersebut meliputi koefisien determinasi, uji hipotesis, uji asumsi klasik, uji reliabilitas, dan uji validitas. Penelitian membuktikan dari hasil uji hipotesis yaitu dengan penyebaran kuesioner. Hasil kuesioner tersebut membuktikan hasil penelitian reliabel serta valid. Hasil uji asumsi klasik menyatakan penelitian ini tidak terjadi multikolinieritas serta heterokedastisitas. Hasil uji F didapatkan dari    perihal ini menandakan bahwasanya kualitas produk, secara simultan citra merek serta harga berdampak signifikan dan positif pada variabel terikatnya yaitu keputusan pembelian. Sementara hasil uji t ditunjukkan kualitas produk dan citra merek secara positif serta signifikan berdampak pada keputusan pembelian produk Garnier di Universitas Islam Batik Surakarta, kemudian variabel harga secara tidak signifikan serta positif berpengaruh terhadap keputusan pembelian produk Garnier di Universitas Islam Batik Surakarta.
Analisis Pemberdayaan Pegawai dan Kinerja Pegawai Terhadap Kesejahteraan Pegawai di UMKM Galeri Belva Batik Kecamatan Burneh Kabupaten Bangkalan
Authors: Bulqiyah Mochammad Hazanal , Sukarno Gendut
Published: March 2022

Usaha Mikro Kecil dan Menengah (UMKM) saat ini mempunyai peran yang penting untuk meningkatkan perekonomian negara, baik negara yang sudah maju maupun negara yang sedang berkembang. Tujuan dari diadakannya studi ini yakni agar dapat mengetahui korelasi daripada pemberdayaan pegawai dan kinerja pegawai terhadap kesejahteraan pegawai di UMKM Galeri Belva Batik. Selanjutnya peneliti menggunakan penelitian kuantitatif sebagai jenis penelitian ini yang mana kuesioner sebagai alat pengukur jawaban dari responden. Populasi yang dipergunakan oleh peneliti yakni para pegawai UMKM Galeri Belva Batik sebanyak 100 orang. Yang kemudian dalam mengumpulkan sampel yakni teknik non probability sampling dan metode purposive sampling, sehingga sampel yang dipergunakan peneliti sebanyak 80 pegawai dan margin eror 5%. Setelah dijawab oleh responden, jawaban tersebut akan dianalisis dengan mempergunakan Smart PLS (Partial Least Square) untuk menguji tingkat kevalidan dan reliabelnya suatu indikator dan variabel penelitian yang mana hal tersebut termasuk kedalam outter dan inner model. Hasil penelitian ini menyimpulkan bahwa pemberdayaan pegawai berpengaruh positif tidak signifikan pada kesejahteraan pegawai dan kinerja pegawai berpengaruh positif pada kesejahteraan pegawai.
Assessment of the posterior risk of sudden death due to cardiovascular diseases at the workplace
Authors: Chashchin Maxim V. , Lezhnev Oleg K. , Atabekov Anton I. , Kajk Elena A. , Bolshakova Ekaterina G.
Published: March 2022

Introduction. The aim of the study was to find the associations between cardiovascular disease and occupational risk factors of sudden death in the context of the St. Petersburg population. It remains relevant and is part of the problem of a significant mortality rate among working-age people in the Russian Federation. Materials and methods. Methods adopted in the study of non-infectious diseases were selected as the primary research methods. The analysis of deaths of employees of enterprises was carried out based on a retrospective cohort. Results. There has been a marked increase in sudden cardiac death (SCD) in the workplace from cardiovascular diseases. The calculation of mortality rates per 10000 workers from cardiovascular diseases showed that the first ranking place in the period since 2016 until 2018 in St. Petersburg was occupied by such types of economic activities as administrative activities (6,05 cases); construction (4,23 cases); provision of electricity, gas and steam (3,63 cases); land transport activities (3,26 cases); financial and insurance activities (3,02 cases) and manufacturing (1,97 cases). The posterior risk of death from diseases of the circulatory system was established to be 1.67 times higher for workers employed in jobs with harmful working conditions. The analysis of SCD showed that the high level of risk for workers is recorded at the age of 50 to 59 years, reaching values of 27,72 (11,33-67,81) (p <0,001). In the course of the study, it was found that the organization of timely medical care in the conditions of health centres of industrial enterprises in the acute period of the development of cardiovascular insufficiency will contribute to a decrease in mortality rates at the workplace by more than three times. Limitations. The study of the causes and indicators of 347 deaths at the workplace was carried out based on official statistics provided by the State Labor Inspectorate in St. Petersburg and registered at industrial enterprises in the period from 2016 to 2018. The study does not include small and medium-sized businesses. Conclusion. The results of assessing the risk of death in the workplace of industrial enterprises in St. Petersburg indicate the need to improve the organization and procedure for investigating, recording and registering such cases in order to establish cause-and-effect relationships.
Influence of the composition of atmospheric air pollution on genotoxic effects in the buccal epithelial cells in children
Authors: Yurchenko Valentina V. , Ingel Faina I. , Malysheva Alla G. , Akhaltseva Lyudmila V. , Krivtsova Elena K. , Yurtseva Nadezda A. , Nikitina Tatiana A. , Ivanova Svetlana M. , Shishkin Dmitry I. , Budarina Olga V.
Published: March 2022

Introduction. This publication presents the third fragment of a comprehensive multi-parameter pilot study to create a methodology for assessing the open-air odor’ impact on human’s adaptive potential. The pilot study was carried out in the little town (50 thousands of inhabitants), mainly the food industry and agro-industrial complex work, but enterprises of 1-2 classes of danger are absent. Air emissions from operating enterprises have a specific odor that causes complaints of inhabitants. Materials and methods. The effects of genome instability (EGI) in children attending kindergartens located at a distance of 1.7-5.9 km from enterprises - the primary sources of odor - were assessed. EGI was determined non-invasively using a micronucleus test on exfoliating cheek epithelial cells. The epitheliocytes from 112 children of 5 -7 years old were examined simultaneously with a collection of atmospheric air samples from the walking areas of the kindergartens which the examined children attended. These atmospheric air samples were taken for gas chromatography-mass spectrometric determination of their chemical composition. Results. Seventy-eight chemical compounds belonging to different classes of chemicals were identified in the air samples. The groups of children from different kindergartens did not differ statistically in any of the 13 assessed indicators of the cytome analysis of the buccal mucosa epithelium cells, and the levels of genotoxic and toxic effects did not go beyond the average expected values presented in literature and our studies for differents groups of comparison. High-level and statistically significant direct correlations between the total content of air pollutants with proven genotoxic activity and the two main indicators of the micronucleus test on cheek epithelial cells: the frequencies of cells with micronuclei and cells with accepted apoptotic bodies were revealed. No correlation was found between summarized levels of the detected chemicals limited concentrations and the results of cytome analysis of children’s buccal epithelial cells. Limitations. correct formation of groups for examination, the severity of the criteria for cytotome analysis and identity of cytogenetic effects identification in the course of cytotome analysis by different researchers. Conclusion. The effects of genome instability in the buccal epithelial cells in children were shown to be mainly associated with the presence of substances with proven mutagenic, carcinogenic and neogenic activities, but not with the total excess of hygienic standards for the content of chemical compounds in the air.
The Mitigating Effect of Supply Chain Risk Management in Marginal Field Oil and Gas Companies in Nigeria
Authors: Erakpotobo Vincent Oyovwevotu , Omo OKEI Justice Oborakpororo
Published: March 2022

Historically, oil and gas was discovered in Nigeria in 1956 by Shell petroleum at Oloibiri now Bayelsa state. The oil and gas industry is divided into upstream, downstream and mid-stream respectively in Nigeria. Each of the petroleum sectors performs different functions in terms of exploration, refining and distributions and with respective supply chains. In course of the supply chain distribution, distractions in form of turbulence and disruption can occur which could have serious effects on operations and performance. Hence this study focused on the mitigating effect of supply chain risk management in marginal field oil and gas companies in Nigeria. It is field survey and case type of research. A total of 687 Management and Senior staff of nine marginal filed oil and gas companies constituted that population while 325 formed that sample size. The main instrument was questionnaire administration and analysed using descriptive statistics. The study found that application and proper management of supply, demand, information, transportation and monitoring risk mitigation strategies are critical factors enhancing reduction of risks in marginal field oil and gas in Nigeria. It therefore recommended that there should proper coordination of information, monitoring, demand and supply chain risk management in order to reduce vulnerability of disruptions and distraction in operations.
CAUSAS DA EVASÃO ESCOLAR NO ENSINO MÉDIO E ENSINO SUPERIOR: QUAL A INTERSEÇÃO?
Authors: Borges Monteiro Vitor , Wagner Martins João
Published: March 2022

Uma série de estudos se dedicam ao estudo da evasão escolar na etapa de ensino fundamental e médio, indubitavelmente devido ao apelo constitucional da universalização do ensino nestes ciclos educacionais. Entretanto, deixa uma lacuna que vem sendo preenchida lentamente por estudos recentes que se dedicam a entender o comportamento da evasão no ensino superior.  Apesar de evidente que houve uma mudança significativa do perfil do universitário brasileiro a partir do sistema de cotas, sabe-se que a heterogeneidade dentro das universidades ainda prevalece. Nesse sentido, o objetivo do trabalho consiste em realizar um levantamento bibliográfico sobre a evasão nos ensinos médio e superior no Brasil e discutir as causas da evasão e comparar suas peculiaridades em cada etapa. Através de um infográfico que mapeia as variáveis por etapa de ensino no tempo, conclui-se que no Ensino Médio as causas da evasão estão relacionadas aos problemas externos ao aluno, como ambiente socioeconômico e cultural, políticas públicas educacionais e também àqueles pertinentes a escola, como relação professor e aluno e tamanho da escola. Já a evasão universitária absorve problemas relacionados a questões pessoais, como aptidão ao curso, filhos, trabalho, distancia etc.
EFFECT OF LASER SHOTS ON THE OPTICAL PROPERTIES OF FE2O3: CUO THIN FILMS PREPARED BY PULSE LASER DEPOSITION TECHNIQUE
Authors: NAEEMA Nadia , JASIM Hanaa E. , HUSSEIN Ahmed Shaker
Published: March 2022

CuO-doped Fe2O3 thin films were deposited onto glass substrates using the Pulsed Laser Deposition (PLD) process at room temperature and a vacuum of 10-2 mbar, utilizing a Nd:YAG laser with a wavelength of 1064 nm, an average frequency of 6 Hz, and a pulse duration of 10 at various laser pulses (300,400 and 500 and).The effect of number of pulsed laser shots on the optical properties of the films was invesigated. UV-VIS spectrophotometer mentioned that the transmittance increases to 90 % when decresing the number of the laser shots. Furthermore, The optical measurements indicate that the Fe2O3:CuO films have a direct Egopt that diminishes as the number of laser pulses increases. The band gap energy of the Fe2O3:CuO found was 3.01 eV. This value was reduced significantly to 3.0 by increasing the number of laser blasts. However, optical constants such as the refractive index (n), the extinction coefficient (k), and the dielectric constant (r, I rise in a predictable manner as the number of laser flashes increases. Key words: CuO –doped Fe2O3; PLD technique ; Thin Film; Optical Properties; Band Gap.
EFFECT OF DIFFERENT FREEZING PERIODS OF SERUM SAMPLES ONCOMMON BIOCHEMICAL TESTS
Authors: SALMAN Alea Farhan , ABD-AL-LATTEF Huda Ibraheem , KHAZEEM Mushtaq Mufleh
Published: March 2022

Blood samples are often collected, stored for certain periods and analyzed in the laboratory, and this affects the results of the analysis. The aim of this study was to determine the analytical persistence of serum samples expose to storage temperature range and times prior to analysis. Materials and methods: Serum samples were obtained from 36 persons. After measuring the fresh sample, the rest of the serum sample was divided into 5 groups and stored at -20 ˚C. A group of sera was kept frozen for up to 42 days then analyzed for stability. A total of 9 chemistry analytics were assayed(glucose, urea, uric acid, total protein, albumin, calcium, lactate dehydrogenase (LDH), and alkaline phosphatase) at each time point. The results were compared with those obtained from the initial analysis of fresh samples. Results: Among the analytics studied, cholesterol was stable in all conditions. Glucose, urea, uric acid, total protein, albumin, calcium, lactate dehydrogenase (LDH), and alkaline phosphatase were changed significantly (P < 0.005). Conclusions: These results can be used to determine which chemical analysis gives incorrect results when exposed to different storage times but some of the chemical analysis was not affected by the delay and storage conditions for up to 6 weeks prior to analysis. Key words: Serum, Stability, Storage Time, Storage Temperature Range.
BURNOUT PARENTAL NO CONTEXTO DA PANDEMIA DE COVID-19
Authors: Alkimim Bruno Melo , Santos Alcione Oliveira dos
Published: March 2022

Introdução: A pandemia da COVID-19 trouxe mudanças relevantes no cenário global, alterando o estilo de vida e o cotidiano dos cidadãos. Nessa perspectiva, medidas como o isolamento social, trabalho remoto e ensino à distância foram adotadas, o que afetou diretamente a saúde mental dos indivíduos. Em consequência disso, destaca-se a síndrome de burnout parental como um dos transtornos frequentes apresentado por alguns pais diante da atual conjuntura, caracterizado pelo cansaço extremo, cobranças pessoais e sentimentos de ineficiência, que comprometem a relação com os filhos. Objetivos: Analisar o burnout parental, de modo a destacar suas causas e impactos durante a pandemia de COVID-19. Material e métodos: Este estudo foi elaborado através do método de revisão integrativa, utilizando ferramentas online de busca de artigos científicos e/ou clínicos publicados entre os anos 2020 e 2021, indexados em fontes multinacionais. Resultados: Dados obtidos de um estudo global envolvendo 42 países, publicado na revista Affective Science, apontam que os desafios na conciliação de tarefas, a sobrecarga e o aumento das responsabilidades culminaram no esgotamento parental. Verificou-se também que países com culturas individualistas são mais propensos ao desenvolvimento de burnout de pais e mães. Já em uma pesquisa realizada pela Universidade do Porto, no período entre a primeira e segunda onda da COVID -19, comparou-se um grupo de pais e mães que viviam com um filho ou mais, observou-se que na segunda onda houve aumento da exaustão, do distanciamento emocional, do contraste e da despersonalização, os quais são características marcantes dessa psicopatologia. Outrossim, uma investigação executada pela Faculdade de Medicina de Ribeirão revelou que, das mães entrevistadas, 34% tiveram sentimentos negativos durante a pandemia, já 47% que não tinham sinais de depressão passaram a apresentá-los, corroborando o impacto negativo do isolamento social em indicadores de saúde mental materna. Conclusão: Nota-se, portanto, que essa mudança na dinâmica familiar presenciada tem levado a um o aumento da incidência de burnout parental, caracterizando um problema de saúde pública. Nesse contexto, mostra-se a importância da busca por ajuda profissional, aliada à uma rotina com introdução de atividades individuais e coletivas que aliviem o estresse, conforme a realidade de cada família.
FATORES DE RISCO PARA O DESENVOLVIMENTO DO MAL DE ALZHEIMER EM POPULAÇÃO GERIÁTRICA
Authors: Fonseca Maria de Fatima Araujo da , Simões Bruno Sena , Amaral Bianca Azevedo Berger , Dias Camila de Faria , Gonçalves Rayane Do Nascimento
Published: March 2022

Introdução: O Alzheimer é uma doença neurodegenerativa que acomete idosos no mundo todo, comprometendo a memória e a cognição dos portadores. Com a expansão da longevidade, a prevalência da doença continua a aumentar, dificultando a rotina de ainda mais famílias e a capacidade funcional dos idosos. Assim, vê-se a importância de compreender os fatores multicausais, como forma de prevenir a doença de Alzheimer. Objetivos: O presente estudo visa realizar uma revisão de literatura acerca dos principais fatores de risco para o desenvolvimento do mal de Alzheimer, a fim de compreender os mecanismos que contribuem para o declínio cognitivo. Material e métodos: Foram realizadas pesquisas no mês de janeiro de 2022 e selecionados artigos na língua inglesa usando os descritores "Alzheimer", "neurology", "geriatric" e "risk factors" entre os anos de 2016 a 2022 em bases de dados da Biblioteca de Saúde Virtual (BVS) e PUBMED. Resultados: Foram analisados 36 artigos relacionados ao tema, sendo que apenas 12 foram selecionados e 24 foram descartados por não tratarem diretamente do tema ou não abordarem o contexto desejado. Dos que foram analisados, elencaram-se que fatores de risco como idade, sexo, hábitos alimentares (micro e macronutrientes dietéticos), estilo de vida, doenças preexistentes (a exemplo de Diabetes Mellitus 2), gene ApoE e outros genes específicos, ainda sob estudo, contribuem para a afecção neurodegenerativa progressiva e sua prevalência. Conclusão: Portanto, conclui-se que a doença de Alzheimer afeta a população em proporções cada vez maiores, haja vista que decorre de múltiplos fatores de risco são comuns na sociedade atual e de demais que ainda estão sob estudo. Além disso, essa doença compromete as estruturas relacionadas com a integração da cognição e do comportamento no indivíduo diagnosticado, também compromete a qualidade de vida daqueles que fazem parte de seu convívio. Nesse sentido, o conhecimento da fisiopatogênia da doença de Alzheimer se mostra muito importante para o desenvolvimento de possíveis diagnósticos precoces e de novas terapêuticas que foquem na origem da doença a fim de evitar sua manifestação.
ANÁLISE DA QUALIDADE DE VIDA DE PACIENTES EM ATENDIMENTO DOMICILIAR ATRAVÉS DOS QUESTIONÁRIOS WHOQOL
Authors: Sousa Letícia Cristina Alves de , Ferreira Bruno Rogério , Tassara Kennia Rodrigues , Moraes Jonathan Ballico de , Wastowski Isabela Jubé
Published: March 2022

Introdução: No Brasil, a saúde é direito de todos e dever do Estado, sendo oferecida através do Sistema Único de Saúde (SUS). O SUS abrangendo desde a Atenção Primária, até o transplante de órgãos, garantindo acesso integral, universal e gratuito para toda a população do país. O atendimento domiciliar tem sido amplamente difundido no mundo e tem como pontos fundamentais o paciente, a família, o contexto domiciliar, o cuidador e a equipe multiprofissional. Objetivo: O presente estudo visa mensurar a qualidade de vida (QV) dos pacientes atendidos pelo Programa Melhor em Casa (MemC) em uma cidade do interior do estado de Goiás. Material e métodos: O projeto de pesquisa foi submetido à Plataforma Brasil e aprovado pelo Comitê de Ética, sob o número 4.348.814. A pesquisa foi desenvolvida em 3 (três) etapas com 28 pacientes. A primeira etapa foi a entrevista inicial do paciente sobre sua percepção de qualidade de vida, utilizando os módulos WHOQOL-OLD e WHOQOL-BREF. A segunda etapa foi a entrevista final do paciente sobre sua percepção de qualidade de vida, utilizando os módulos validados. A terceira etapa foi a análise estatística. Resultados: A maioria dos pacientes em atendimento domiciliar são do gênero feminino e com idade acima de 60 anos. As patologias mais frequentes foram a Hipertensão Arterial (53,6%), Acidente Vascular Cerebral - AVC (46,4%) e Diabetes (35,7%), todas Doenças Crônicas Não-transmissíveis (DCNT). O aumento do escore da QV foi observada na maioria dos pacientes entrevistados. Pacientes com doenças crônicas e/ou degenerativas, geralmente vivenciam piora progressiva, pois estas não permitem que haja recuperação do que foi perdido pelo paciente, como autonomia e realização das atividades diárias. Todavia é possível estacionar a progressão da doença, com as condutas realizadas no atendimento domiciliar. Conclusão: Sugere-se que o atendimento domiciliar proporcionado pelo MemC impeça a progressão das patologias, principalmente pela adoção de medidas paliativas e reabilitação através do atendimento multidisciplinar, além de proporcionar estabilidade no quadro patológico do paciente, o que se torna positivo do ponto de vista da qualidade de vida.
IINTERVENÇÕES DE UMA EQUIPE DE SAÚDE DO TRABALHADOR EM TEMPOS DA COVID-19: RELATO DE EXPERIÊNCIA.
Authors: Ramos Adinaura da Gama , Santos Ana Lidia Coutinho dos , Araujo Erizani Sampaio , Pureza Rosireno Alfaia , Moraes Alda Do Socorro Cardoso
Published: March 2022

Introdução: O Setor Saúde do Trabalhador - SESAT é composto por equipe multiprofissional que atua nos eixos de promoção e vigilância em saúde e perícia médica. Com o advento da pandemia da COVID-19 e a necessidade de manter o distanciamento social, diversas atividades planejadas para o ano de 2020 precisaram ser interrompidas para evitar aglomerações. Serviços presenciais de perícia médica deram lugar aos atendimentos psicológicos na modalidade remota. Ações de vigilância dos ambientes laborais foram intensificadas através de restrições de uso de áreas comuns, como refeitórios, auditórios e consultórios, a bem da saúde pública. Objetivo: Relatar a experiência laboral de uma equipe de servidores de instituição pública federal acerca das demandas de trabalho vivenciadas no contexto da pandemia da COVID-19. Material e métodos: O estudo consiste em um relato de experiência das ações vivenciadas em um setor de saúde do trabalhador de uma instituição pública de pesquisa em saúde no período de março de 2020 a janeiro de 2022. Participaram do estudo os profissionais do setor que atuam nos eixos de promoção e vigilância em saúde. Resultados: Realizadas diversas reuniões com grupo estratégico da instituição para implantação do Plano de Contingenciamento para contenção da pandemia da COVID-19 no ambiente laboral com base no modelo dialogado com Ministério da Saúde. Dentre as prioridades do Plano definiu-se pela modalidade de revezamento de trabalho remoto e presencial, bem como o afastamento das gestantes, puérperas, idosos e portadores de doença crônica. As ações de educação em saúde foram restritas às modalidades virtuais com elaboração de banners digitais com orientações sobre distanciamento social; uso adequado de EPIs; lavagem correta das mãos; uso de álcool em gel a 70% e uso obrigatório de máscaras. Foram realizados testes de COVID, RT-PCR em parceria com a seção de virologia, assim como a imunização dos trabalhadores contra gripe sazonal e COVID-19 com o apoio da Secretaria Municipal de Saúde de Ananindeua. Conclusão: A atuação da equipe de saúde do trabalhador contribuiu de maneira crucial para a efetivação das medidas de controle e prevenção da pandemia no ambiente laboral.