bluuebunny/crossref_metadata_2025 huggingface dataset:
It’s Time to Entrust Saint Januarius’s Blood to Microchemistry
Authors:   University of Campania Luigi Vanvitelli, I-80138 Napoli, Italy, Bruno M Strangio , Francesca Riotto ,   Diocese of Oppido Mamertina-Palmi, Via Rocco Pugliese38, I-89015 Reggio Calabria, Italy, Fazio Giovanni ,   3 University of Messina. Department of Mathematical and Computer Sciences, Physics Sciences and Earth Sciences. Viale Ferdinando Stagno d’Alcontres 31, I-98166 Messina, Italy
Published: January 2025

This article, which follows two of our previous writings, emphasizes the need to analyze a small sample
from the ampoules containing the blood of Saint Januarius, preserved in the Cathedral of Naples, through
microchemical methods. This step is essential to definitively determine the nature of the substance
within. This action would be in the interest of both the Roman Catholic Church and the faithful. Saint
Januarius was martyred at the beginning of the 4th century AD, and the first blood liquefaction event
occurred at the end of the 14th century AD. Therefore, this event took place in the Middle Ages, a time
when many false relics were circulating in Europe. We believe this request should be granted, at the very
least, it should be possible to implement the recommendations outlined in our first article.
A Novel Transthyretin Variant (p.Phe-84-Tyr) for Hereditary Transthyretin Amyloidosis with Polyneuropathy and Early Ocular Findings
Authors:   Department of Neurology, Instituto Nacional De Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, Cárdenas-Soto Karla , Arumir-Lira Alechka ,   Department of Neurology, Instituto Nacional De Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, Gonzalez-Duarte Alejandra ,   Department of Neurology, Instituto Nacional De Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico,   Department of Cardiology, Instituto Nacional De Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico,   Centro de atención integral del paciente con diabetes. Instituto Nacional De Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico,   Instituto de Oftalmología Fundación Conde de Valenciana. I.A.P., Mexico City, Mexico,   Department of Neurology, New York University School of Medicine New York, New York, New York, USA, Rivera-De La Parra David ,   Instituto de Oftalmología Fundación Conde de Valenciana. I.A.P., Mexico City, Mexico,   Department of Neurology, New York University School of Medicine New York, New York, New York, USA, Reyes Pablo Hernandez ,   Department of Cardiology, Instituto Nacional De Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico
Published: January 2025

Hereditary transthyretin amyloidosis (hATTR) is a rare disease that affects multiple systems and is
triggered by a mutation in the transthyretin (TTR) gene. This report introduces a new pathogenic
variant, Phe84Tyr, identified in a patient with no known family history of amyloidosis. The patient
exhibited polyneuropathy, cardiomyopathy, and significant ocular involvement, potentially a unique
characteristic of this variant.
Putting on a “Human Face” for Medical Experience Using AI: The Case of Prescription Weight Loss Drugs
Authors:   Tactical Data Group, Stafford, Virginia, USA, Moskowitz Howard R ,   Mind Genomics Associates, Inc., White Plains, New York, USA, Wingert Sharon ,   Tactical Data Group, Stafford, Virginia, USA, Anderson Tonya ,   Tactical Data Group, Stafford, Virginia, USA, Rappaport Stephen D ,   Stephen D. Rappaport Consulting LLC, Norwalk, Connecticut, USA, Saharan Sunaina ,   Global Medical Health Forum, Brooklyn, New York, USA,   Experience Transformation, Humana, San Diego, California, USA, Bayad Jana ,   Experience Transformation, Humana, San Diego, California, USA
Published: January 2025

This paper introduces the use of AI as a potential tool for education of medical professionals. The
specific topic is the case of prescription (Rx) weight loss drugs commonly marketed directly to patients
in a variety of media. The paper introduces the method of a “fly on the wall,” which brings to life
the interaction among professionals dealing with specific medical issues, with simulations of patient
reactions woven into the simulation. The paper then brings to life the organizing principle of mind-sets
and how they deal with the topic. The paper finishes by instructing AI to create a set of 10 issues and
comparing the full narrative format to a more conventional clinical description. The contribution of the
paper is the effort to give medical professionals a sense of the personal experiences of those involved in
the topic, doing so by AI simulation using ChatGPT 3.5 and accessed through the Idea Coach feature of
the Mind Genomics platform, BimiLeap.com.
Expediente
Authors: Paubrasilia Revista
Published: January 2025

Expediente da revista Paubrasilia. Ano 2025. Publicação contínua.
Overview and trends in forensic palynology based on a scientometric study in the PubMed database
Authors: Silveira Agna Souza , Novais Jaílson Santos de
Published: January 2025

Pollen grains found on human bodies, objects, and in the environment can correlate and reveal potential forensic significance. Understanding the evolution of production and scientific information in this field contributes to the real-world application of evidence gathered through research. This study analyzes scientific literature on forensic palynology indexed in the PubMed database to outline a scientometric overview of the area. Bibliometric indicators from the retrieved publications were systematically organized and analyzed descriptively. Simple textual statistics, word clouds, and similarity analyses were applied to the corpus generated from the abstracts of the studies using IRaMuTeQ. The search yielded 73 publications, published between 1997 and May 2022. The most frequently cited terms were pollen (n = 261) and forensic (n = 144). Research in this field expanded from 2006 onward, with a notable contribution from P. Wiltshire, who authored 11 papers, and from the journals Forensic Science International (n = 19), Journal of Forensic Sciences (n = 16), and Science & Justice (n = 8). Forensic palynology research is expanding and can support professional practice in the criminal field.
THE USE OF DEIXIS IN EFL CLASSROOM INTERACTION: A PRAGMATIC STUDY OF SIXTH-SEMESTER STUDENTS OF THE ENGLISH EDUCATION STUDY PROGRAM AT NUSA NIPA UNIVERISTY
Authors: Timbu Maria Elisabeth Ina , Balik Lusiana Mariyeta , Kartini Maria
Published: January 2025

Research has shown that EFL learners often face challenges with deictic expressions, leading to communication errors. The author wanted to examine whether similar problems exist among sixth-semester English Education students at Nusa Nipa University by analyzing the types and dominant deixis in classroom interactions. Applying Levinson's (1983) theory, this research uses Creswell's (2009) method for in-depth analysis. Data were collected through audio recordings and field notes during eight class meetings, then transcribed and coded for thematic analysis. Miles & Huberman's (1994) technique and Walizer's (1990) formula were used to measure the types of deixis and the dominant deixis used. This analysis reveals that five types of deixis are used: person deixis, time deixis, place deixis, discourse deixis, and social deixis. A total of 979 deixis were identified, with person deixis being the most dominant with 70.48%, accounting for 690 occurrences. “We” was used 194 times, reflecting the collaborative nature of group work, while ‘you’ appeared 132 times, indicating direct engagement with the audience. The findings highlight the role of deixis in shaping academic communication and interaction, emphasizing its importance in effective classrooms.
A SOCIOLINGUISTICS ANALYSIS OF SPEECH STYLE IN ELLEN'S BRIELLE INTERVIEW
Authors: Hasan Hani Firlyali , S Dwi Triana , Matanari Desna Uli , Simangunsong Anisyah Srirezeki , Rangkuti Rahmadsyah
Published: January 2025

This study conducts a sociolinguistic analysis of the speech styles exhibited during the interview between Ellen DeGeneres and three-year-old Brielle on The Ellen Show. Utilizing a qualitative case study approach, the research examines the dynamics of spoken language within a popular media context, focusing on how age and social context influence communication styles. The analysis identifies five distinct speech styles based on Joos's (1967) classification: formal, casual, consultative, intimate, and frozen. The findings reveal that Ellen employs a blend of formal and casual styles when introducing Brielle, transitioning to a more relaxed and engaging tone as the conversation progresses. Brielle's responses reflect a casual style that fosters relatability while showcasing her knowledge of complex subjects like the periodic table. The consultative style emerges during educational exchanges, where both speakers engage in informative dialogue. Additionally, intimate moments are highlighted through interactions with Brielle's mother, emphasizing familial closeness. This study contributes to the understanding of how speech styles adapt in response to varying social contexts and age differences, illustrating the intricate relationship between language and interpersonal dynamics in televised interviews. The results underscore the effectiveness of Ellen's communicative approach in creating an inviting atmosphere that resonates with a diverse audience, ultimately enhancing viewer engagement and understanding of complex topics through accessible dialogue
MENJADI ETNOGRAFER TRANSMANUSIA UNTUK PENELITIAN HUMANIORA MULTISEMESTA
Authors: Saputra Ardi Wina
Published: January 2025

Saat ini kita sedang berada pada era revolusi digital, tepatnya revolusi kuantum kedua. Perlahan manusia mulai meninggalkan era revolusi industri 4.0 dan beranjak ke tahap selanjutnya yaitu masyarakat cerdas (smart society) 5.0. Virtualitas menjadi kunci utama, ranah konvensional perlahan telah berubah menjadi ranah multisemesta. Ranah yang sangat digandrungi oleh generasi figital (fisik dan digital). Menghadapi ranah yang terkoneksi melalui web 3.0 itu, segala kajian ilmu ditunutut untuk beradaptasi agar tetap eksis, salah satunya adalah etnografi. Tujuan penelitian ini adalah untuk untuk mengurai kembali kajian etnografi di wilayah digital serta menemukan alternatif yang dapat dilakukan oleh etnograf agar mampu beradaptasi menjadi etnografer transmanusia demi memasuki ranah penelitian baru, ranah multisemesta. Metode penelitian ini adalah penelitian kualitatif dengan pendekatan grounded theory. Hasil penelitian ini adalah menemukan jenis kajian etnografi yang dapat digunakan di ranah multisemesta, dan menemukan usaha untuk menjadi etnografer transmanusia yang dapat melakukan penelitian pada ranah daring.
UNCOVERING HIDDEN MESSAGES: AN ANALYSIS OF METAPHORS IN JKT48'S "MAHAGITA" ALBUM
Authors: Zahra Intan Karima , Wibowo Hanafi
Published: January 2025

This research examines the metaphorical language in JKT48's Mahagita album to explore how figurative expressions convey deeper emotions and themes within the lyrics. By applying Lakoff and Johnson's Conceptual Metaphor Theory, the study classifies metaphors from selected songs into three types: structural, ontological, and orientational, each contributing to themes such as love, hope, struggle, and personal development. This qualitative descriptive analysis focuses on the lyrics of eleven songs to uncover how these metaphors enhance listeners' emotional engagement and comprehension. Findings indicate that ontological metaphors represent the largest segment, accounting for 47.5%, illustrating abstract feelings through tangible comparisons, such as “Hidup bagaikan pesawat kertas” (Life is like a paper airplane), which highlights the unpredictability and fragility of life. Through metaphor, the lyrics of JKT48 establish a profound emotional connection that resonates with listeners, demonstrating the effective application of figurative language in music to convey intricate emotions and concepts.
PERGANTIAN TOKOH UTAMA DALAM PERANAN NARATIF PADA NOVEL TEMPAT PALING SUNYI KARYA ARAFAT NUR: KAJIAN NARATOLOGI A.J. GREIMAS
Authors: Firismanda M.A. Haris , Maghfiro Nuzula
Published: January 2025

Kajian ini menganalisis mengenai pergantian tokoh utama Mustofa ke tokoh “Aku” yang memiliki peran penting. Utamanya  dalam upaya membangun unsur-unsur naratif pada novel Tempat Paling Sunyi karya Arafat Nur melalui perspektif naratologi AJ Greimas dengan memperhatikan skema aktan yang saling terjalin terhadap suatu teks naratif tersebut. Selain itu, pembahasan ini juga melihat posisi Mustofa sebagai tokoh utama dalam kaitannya dengan upayanya mencapai objek. Dalam analisis ini, dijelaskan mengenai berbagai bentuk penghalang ketercapaian objek tersebut, serta peran "Aku" sebagai pihak yang membantu Mustofa untuk mewujudkan objek. Hal ini menjadi bagian dari usaha untuk membangun kelanjutan unsur naratif dalam cerita, terutama dalam konteks hilangnya keberadaan tokoh utama dalam novel tersebut. Selain itu, ditemukan adanya relasi tokoh “Aku” terhadap Mustofa dalam proses identifikasi tokoh untuk meneruskan terhadap pencapaian objek.
A EUPHEMISM ANALYSIS IN THE 2024 INDONESIAN PRESIDENTIAL ELECTION DEBATE
Authors: Siahaan Rachel Pratiwi , Bacas Chintami Angelica , Daulay Olga Adelia , Sembiring Teresia Anjelina , Rangkuti Rahmadsyah
Published: January 2025

This study analyzes the use of euphemisms in the debate of the 2024 Indonesian presidential candidates. Candidates used euphemisms to discuss sensitive issues such as corruption, human rights, and social inequality without causing conflict or harming certain parties. Using a qualitative approach, data were taken from the transcript of the debate broadcast on the official YouTube channel of the Indonesian General Elections Commission (KPU RI). The euphemisms presented were based on Warren’s theory (1992), including derivation, compounding, and blending. The results showed that 15 euphemisms were identified from the debate; 8 derivations, 5 compoundings, and 2 blends, of which derivation was the most dominant euphemism. Euphemisms helped candidates convey criticism and sensitive issues more subtly, maintain their public image, and create a more friendly and non-confrontational debate atmosphere. Euphemisms are essential in political communication, especially in Indonesian culture, which priorities gentle and indirect communication. This study contributes to understanding how language can be used to influence public perception and voter decision-making in important political events.
STRATEGI KRITIK DALAM DEBAT CALON PRESIDEN DAN WAKIL PRESIDEN 2024: KAJIAN PRAGMATIK
Authors: Khoironi Haris , Mahbub Moh. Tarojjil , Nugroho Miftah
Published: January 2025

Penelitian ini mengulas strategi kritik yang muncul dalam debat calon presiden dan wakil presiden 2024 dengan menggunakan metode deskriptif kualitatif. Sumber data pada penelitian ini adalah video youtube berjudul “[ FULL ] DEBAT PERTAMA CALON PRESIDEN 2024” yang dirilis pada tanggal 12 Desember 2023, “[ FULL ] DEBAT KEDUA CALON PRESIDEN 2024”, yang dirilis pada tanggal22Desember 2024, “[ FULL ] DEBAT KETIGA CALON PRESIDEN 2024”, yang dirilis pada tanggal 7 Januari 2024,  dan “[FULL ] DEBAT KEEMPAT CALON PRESIDEN 2024” yang dirilis pada tanggal 21 Januari 2024. Video tersebutdiakses pada tanggal 12 April 2024. Hasil analisis di atas, didapati bahwa terdapat 23 data ujaran kritik. Dalam konteks debat calon presiden dan calon wakil presiden, sebanyak 9 ujaran kritik ditemukan, baik yang dilakukan secara langsung maupun tidak langsung. Dari ujaran yang kritik tersebut, 3 di antaranya menggunakan penilaian negatif secara langsung, 1 menunjukkan ketidaksetujuan, 2 menyederhanakan masalah, 2 menyampaikan keraguan, dan hanya 1 mengajukan pernyataan memancing. Di sisi lain, strategi kritik tidak langsung mencakup 14 data, dengan penggunaan koreksi pada 2 data, indikasi standar pada 2 data, pengajaran pada 3 data, permintaan perubahan pada 1 data, saran untuk perubahan pada 2 data, ekspresi ketidakpastian pada 1 data, dan petunjuk lainnya pada 3 data.
KONSEP PENDIDIKAN MENURUT IBNU KHALDUN DALAM KERANGKA PRAGMATIS-INSTRUMENTALIS
Authors: Mahmudah Umi , Mardiatul Hayat  , Yuangga Kurnia Yahya
Published: January 2025

The study aims to analyze Ibn Khaldun's (1332-1404) thoughts on education and relate them to the pragmatic-instrumental perspective initiated by John Dewey (1859-1952), especially to become the basis for innovation in contemporary Islamic education. This study is a qualitative study with data sources from the library. This study concludes that Ibn Khaldun's thinking has educational goals, output, processes and content that overlap with pragmatic education initiated by John Dewey. Another important thing is that the relationship of thought between the two shows that educators and managers of Islamic educational institutions do not need to feel unfamiliar with the instrumental pragmatism approach which is government policy and society's demands. However, as Ibnu Khaldun did, they can formulate innovations in education according to the context of the needs of the times and the basis of Islamic epistemology.
MENGHIDUPKAN ILMU AGAMA DI LEMBAGA PENDIDIKAN TINGGI
Authors: Priyono Sugeng
Published: January 2025

This study aims to explore strategic approaches in learning Islamic religious education in higher education to improve the integration of knowledge, charity, and ikhlas in the lives of students. Using a descriptive qualitative method, this study analyzes the implementation of practice-based learning in Trilogi University, including audiences to MUI, halal product assistance training, and seminars related to national values and technology. The findings show that practice-focused learning methods are able to build students' spiritual awareness, strengthen national values, and improve understanding of the concept of maqashid sharia in daily life. A visit to MUI enriched students' insights into the role of ulama in maintaining community harmony, while halal training emphasized the importance of the halal industry in a global context. The religion and technology seminar provided a critical perspective on the integration of Pancasila values in the development of modern technology. In conclusion, a holistic approach in learning Islamic religious education not only improves theoretical understanding, but also prepares students to become individuals with character, competitiveness, and social responsibility.
ISLAMIC PARENTING ANAK USIA DINI DALAM PERSPEKTIF JAMAL ABDURRAHMAN
Authors: Nuraini Suci
Published: January 2025

This study aims to analyse the application of prophetic parenting in early childhood based on the views of Jamal Abdurrahman. The research was conducted through a literature study with a qualitative approach and is descriptive-analytical in nature. Primary data was obtained from the book Islamic Parenting: Child Education The Prophet's Method. The research was conducted by content analysis of Jamal Abdurrahman's work. The results showed that prophetic parenting aims to form children who are devoted to Allah SWT, shalih/shalihah, noble, obedient, responsible, and brave. The material taught includes faith education, morals, worship, and science. The methods used by the Prophet include setting an example, giving advice, getting used to goodness, utilising free time, giving punishment, and instilling motivation. Evaluation is carried out systematically through daily observations, weekly and monthly records with indicators that refer to the target learning material. This research confirms the importance of applying Islamic values in educating children.
METAVERSE TEKNOLOJİSİNİN FİKRİ MÜLKİYET HUKUKUNDA DOĞURABİLECEĞİ OLASI SORUNLAR
Authors: Özkan Üner Zehra
Published: January 2025

Sanal evren veya dijital evren olarak da anılan metaverse gelişmekte olan teknolojilerden biridir. Bu teknolojinin hukukun tüm alanlarını oluğu gibi fikri mülkiyet hukukunda yansımaları olmuştur. Önceleri sadece fiziki varlığı olan mal veya hizmetler söz konusu iken bu teknolojilerle birlikte sanal mallar, hizmetler ve tasarımlar gündeme gelmiştir. Bunların fiziki dünyada karşılığı olmak zorunda değildir ancak karşılığı da olabilir. Günümüzde artık fiziksel dünya ile dijital/sanal evren çok daha fazla etkileşim içerisindedir. Hatta Türkçe’ye fijital olarak da tercüme edilen phygital kelimesi doğmuştur. Tüm bu hususlar özellikle marka ve tasarım hukukunda ele alınması gereken sorunlar olarak karşımıza çıkmaktadır. Bunun dışında avatarlar, sınırsızlık, kullancılar tarafından yaratılan içerikler ve elbette NFT’ler telif hakları bakımından yeniden değerlendirilmesi gereken sorunlardır. Tüm bunların yanı sıra fiziki dünyada öngörülen sınırlamaların metaverse ortamında hangi kapsamda uygulanacağı da bir başka sorun olarak karşımıza çıkmaktadır. Bu çalışmada bütüncül bir yaklaşımla metaverse teknolojisinin fikri mülkiyet hukuku alanında doğurduğu tüm bu soru ve sorunlar tespit edilmiştir.
Criminal liability of an accomplice in bribery without criminal liability of the perpetrator – pro et contra
Authors: Zahyney-Zabolotenko Zoya
Published: January 2025

Extended Abstract. The article highlights the question of whether it is possible to pass a guilty verdict against an accomplice in bribery in the event that the executor - an oﬃcial who allegedly received an illegal benefit through the accomplice, was not brought to criminal liability. That is, in the case when there is no indictment of the court regarding the oﬃcial’s criminal liability under Art. 368 of the Criminal Code of Ukraine. It has been established that aiding and abetting in the commission of a criminal oﬀense should be considered exclusively within the scope of complicity, and therefore aiding and abetting, like complicity in general, should be characterized by both objective and subjective signs, in particular, such an objective sign as joint activity accomplices The indicated sign follows from such a feature of complicity as conspiracy to commit the relevant criminal oﬀense, which is inherent even in the case of bribery with the use of an accomplice.

Two levels of the commission of a criminal oﬀense are distinguished if an accomplice is involved in the performance of the objective party, namely the primary level of receiving an unlawful benefit by an oﬃcial, and the secondary level — the actual assistance in bribery. The indicated levels form a single criminal oﬀense for accomplices — bribery, the commission of which is determined by the signs of complicity of an objective and subjective nature.

The absence of a properly confirmed fact of committing the primary level of bribery (the fact that the oﬃcial received an unlawful benefit) indicates that there is no secondary level of committing bribery, namely aiding and abetting bribery. It was concluded that aiding and abetting bribery is a type of complicity in the commission of a criminal oﬀense, it should have objective and subjective signs of complicity. Accordingly, the conviction of a person for aiding and abetting an illegal benefit by an oﬃcial without a properly established fact that he received such an illegal benefit contradicts established approaches in the theory of criminal law and violates the principle of presumption of innocence.

Key words: complicity, aiding and abetting bribery, mediation, criminal responsibility, criminal oﬀense, corruption criminal oﬀense, bribery, mediation, conspiracy, presumption of innocence, qualification.
Selected legislation problems in Poland
Authors: Niesiołowski J.
Published: January 2025

The author presents selected problems regarding the legislative process. Those issues include:
◦ the system of sources of law in Poland as the outcome of the legislative process,
◦ the impact of Poland’s membership in the European Union on the legislative process,
◦ the preparation of parliamentary bills by the Council of Ministers
Legal monitoring as a component of scientific support for the law-making process
Authors: Parkomenko N. M.
Published: January 2025

The necessity and importance of monitoring the current legal framework in the course of scientific support for the preparation of the Scientific Concept for the Development of Legislation of Ukraine for the Cabinet of Ministers of Ukraine were emphasized. This is due to the urgent need to strengthen the quality of bills, their objective predetermination; reduction of excessive activity of parliamentarians; the predicted development of the system of law and the system of legislation of Ukraine in accordance with the constitutionally enshrined strategy of state-legal development, the activities of the Cabinet of Ministers of Ukraine.

Accordingly, the entire legal array requires an audit of compliance with objectively existing social relations (identification of outdated legal acts); the existence of an objective need for legal influence; constitutionality and compliance with international principles and European standards; consistency between legal acts of different legal force and different subjects of law-making; ability to exercise regulatory influence on social relations; the existence of mechanisms for implementing legal provisions and overcoming the declarative nature of law, etc.

That is why legal monitoring is used as a systematic comprehensive control legal tool, which should be aimed not only at tracking, analyzing and evaluating the implementation of adopted normative legal acts, but also predicting the consequences of the adoption of normative legal acts in their preparation.

Legal monitoring has several stages, according to which the object, subject and purpose, methods of monitoring, form and content of the Concept, a list of means and techniques necessary to achieve the goal are determined. The subject of legal monitoring is the essence and content of existing legal acts, legal acts of the EU, the practice of the European Court, law enforcement practice, judicial practice, acts of official interpretation of the norms of law, legal doctrine, etc.

Appropriate legal monitoring will contribute to the definition of optimal and rational ways of legal development, which includes not only the system of law and the system of legislation, but also legal consciousness, legal culture and law and order.
Criminal law protection of state security of Ukraine
Authors: Kvasha O. O.
Published: January 2025

The ten-year-long Russian-Ukrainian war actualized not only the problem of improving domestic criminal legislation, but also the revision of established concepts and approaches in legal science. First of all, it is about the criminal law protection of the foundations of national security. Since 2014, the number of crimes against the foundations of Ukraine’s national security has increased exponentially. The history of Ukraine in the 21st century shows that a weak state is unable to protect the rights and freedoms of its citizens guaranteed by the Constitution of Ukraine. Therefore, the priority goal of the national security strategy is undoubtedly the security of the state. It is the state that is the imperative of the hierarchy of values of criminal law protection, because its vulnerability and insecurity causes threats to every person and poses a danger to Ukrainian society as a whole. The state has the duty to create an effective system of protection of its own security to ensure the rights and freedoms of its citizens, guaranteed by the Constitution of Ukraine.
There is a need to revise the structure of the Criminal Code of Ukraine and its terminological apparatus, in particular the title of the first section of the Special Part. Ukrainian realities show that the activities of criminal organizations such as «DPR» and «LPR» are directed against the Ukrainian state, and therefore they cannot be recognized as purely terrorist. «State security» and «state security» in the criminal law dimension are identical, like «human rights» and «human rights». In this context, the position of the developers of the new Criminal Code of Ukraine, where book entitled «Criminal offenses against the state and national security of Ukraine» takes place, is important. The importance of the state as an object of criminal law protection has been downplayed at all levels in an extremely dangerous and short-sighted way for many years. A weak and unprotected state is unable to protect its citizens, their rights and freedoms guaranteed by the Constitution of Ukraine. Effective criminal law protection of state security is a «conditio sine qua non» for the protection of human rights and freedoms in Ukraine. Reasonable expediency of changing the title of Chapter I of the Special Part of the Criminal Code to «Crimes against the State», which, in particular, should provide for the criminal liability of criminal organizations of anti-state/anti-Ukrainian orientation.
The Hubble Sphere Mass-Gap Leads to a Gravitational Acceleration Gap That Could be Linked to Milgrom MOND
Authors: Haug Espen
Published: January 2025

The Hubble sphere leads to a mass gap that could potentially explain Milgrom's MOND from a new perspective. Haug [1] has recently demonstrated that the Hubble sphere likely must have a mass gap equal to m_g=m_p^2/M_u approx 10^{-69} kg, where M_u is the mass in the Reissner-Nordström extremal universe. Alternatively, m_g=m_p^2/2 M_c, where M_c is the critical Friedmann mass. This leads to a gravitational gap of about 10^{-10} m/s^2. The gravitational gap is also identical to Gm_g/l_p^2=GM_u/R_H^2=cH_0=a_p/f_{c,p}}, where a_p is the Planck acceleration and f_{c,p}=c/lambda_u t_p=l_p/lambda_u is the reduced Compton frequency over the Planck time window. This seems to provide a plausible explanation for the minimum acceleration, similar in value to found by Milgrom \cite{Mil83} MOND from calibration to galaxy rotation observations. This seems to implies that dark matter is not needed, but that the universe has a minimum gravitational acceleration due to a Hubble sphere mass gap.
Classification by magnetic susceptibility and petrography of NWA 17204, polymict eucrite.
Authors: Garcia Jose , Pérez Sonia
Published: January 2025

In September 2024, a grey rock, weighing 670 grams, arrived at our laboratory, on which numerous dark clasts and metallic particles could be seen, within a fine-grained, dispersed, fragile and easily disintegrable matrix. The analyses concluded that it was a polymictic eucrite, and its official classification was presented, which ends on December 9, 2024 with the name NWA 17204.
Financial Performance: Pasuruan Regional Revenue and Expenditure in 2018-2023
Authors: Wibisono D. , Annisa I. D. , Almanikma M. , Wanodya R. A. , Ningtyas S. F. , Hapsari M. T.
Published: January 2025

This research effort aims to conduct a comprehensive analysis on the fiscal performance of Pasuruan Regency from 2018 to 2023 and to evaluate the efficiency of regional budget management. The results of the decentralization ratio calculation get an average of 20.92% with a sufficient performance. The results of the calculation of the expenditure growth ratio got an average of 3.45% with poor performance. The ratio of operational expenditure to capital expenditure received an average of 65.36% with good performance. The ratio of capital expenditure to total expenditure got an average of 13.16% with good performance. The ratio of direct and indirect spending to total spending has poor performance results. The tax effectiveness ratio got an average of 97.50% with quite effective performance. The results of this study are expected to be an input for the Pasuruan Regency government which aims to improve budget efficiency and strengthen regional financial autonomy.
Perilaku Penggunaan Gawai pada Kualitas Hafalan Santriyah Rumah Qur'an Hafidzatun Qanitaat
Authors: Harum Kusumanafisa Shabira , Nuraryo Imam
Published: January 2025

Penelitian ini bertujuan untuk mengidentifikasi faktor-faktor internal dan eksternal yang mempengaruhi kualitas hafalan Al-Qur'an di kalangan santriyah Rumah Qur'an Hafidzatun Qanitaat, serta melepaskan peran gawai dalam mendukung atau menghambat proses hafalan. Penelitian dilakukan dengan metode deskriptif kualitatif melalui wawancara terbuka dengan santriyah yang berusia 18–27 tahun. Teori yang digunakan adalah Teori Komunikasi Transendental yang bermakna perilaku komunikasi yang terjalin antara seorang hamba dengan Tuhannya. Hasil penelitian menunjukkan bahwa faktor internal seperti rasa malas, bosan, dan hubungan yang tidak harmonis dengan orang lain menjadi hambatan utama dalam proses hafalan. Sedangkan faktor eksternal meliputi tuntutan perkuliahan, lingkungan pertemanan yang kurang mendukung, serta penggunaan gawai yang tidak terkontrol. Meski gawai sering menjadi sumber distraksi, hasil wawancara juga mengungkapkan manfaat positif seperti kemudahan mengakses aplikasi Al-Qur'an untuk muroja'ah dan mendengar murottal, serta penggunaan untuk kebutuhan akademik. Pengaruh negatif gawai lebih dominan ketika penggunaan tidak diatur, dengan banyak santriyah melaporkan penurunan kualitas hafalan akibat godaan media sosial dan hiburan digital. Beberapa santri melaporkan perbedaan signifikan dalam kecepatan dan fokus hafalan antara saat menggunakan gawai dan tanpa gawai. Namun, sebagian besar mengakui bahwa gawai juga menjadi alat bantu yang berguna jika digunakan secara bijak. Penelitian ini menyimpulkan bahwa keberhasilan hafalan dipengaruhi oleh pengendalian diri para santriyah dalam mengelola waktu, emosi, dan teknologi. Selain itu, dukungan lingkungan yang positif, baik dari asrama maupun pertemanan, juga menentukan keberhasilan program hafalan. Diperlukan strategi manajemen waktu dan regulasi penggunaan gawai yang lebih efektif untuk meningkatkan kualitas hafalan santriyah.
Hubungan Dukungan Keluarga Terhadap Kualitas Hidup Lansia Penderita Penyakit Jantung Hipertensi di RSI Siti Rahmah Padang
Authors: Sjaaf Fidiariani , Khansa Indi Dinah , Maribeth Annisa Lidra
Published: January 2025

Latar belakang: Hipertensi merupakan penyakit tidak menular dengan kejadian tertinggi pada lanjut usia. Hipertensi yang tidak terkontrol akan merusak organ target salah satunya pada penyakit jantung hipertensi. Manifestasi klinis dan pengobatan berpengaruh terhadap kualitas hidup seseorang. Dukungan keluarga berperan dalam meningkatkan kualitas hidup. Tujuan: Untuk mengetahui hubungan dukungan keluarga terhadap kualitas hidup lansia penderita penyakit jantung hipertensi di RSI Siti Rahmah. Metode: Ruang lingkup penelitian ini adalah ilmu kardiovaskular, ilmu psikiatri dan ilmu kesehatan masyarakat. Penelitian dilakukan pada bulan Agustus sampai dengan September 2023. Jenis penelitian adalah kuantitatif. Populasi terjangkau pada penelitian adalah penderita penyakit jantung hipertensi di RSI Siti Rahmah berusia 60 tahun ke atas sebanyak 46 sampel dengan teknik purposive sampling. Analisis data univariat disajikan dalam bentuk distribusi frekuensi dan analisis bivariat menggunakan uji chi-square, pengolahan data menggunakan komputerisasi program SPSS versi IBM 25.0. Hasil: Gambaran dukungan keluarga dan kualitas hidup lebih banyak adalah buruk dengan nilai masing-masing 25 dan 34 orang, terdapat hubungan bermakna dukungan keluarga dengan kualitas hidup lansia penderita penyakit jantung hipertensi di RSI Siti Rahmah (p=0,001). Kesimpulan: Umumnya dukungan keluarga dan kualitas hidup pasien penyakit jantung hipertensi di RSI Siti Rahmah Padang dalam kategori buruk dengan hubungan bermakna secara statistik.
Profile of Skin Diseases in The Ederley at Nursing House Surakarta
Authors: Mawardi Prasetyadi , Oktavriana Triasari , Murastami Ammarilis , Murasmita Alamanda , Pradestine Sesia , Esa Putri Osdatilla Esa , Lidjaja Lifesia Natali , Alia Vrenda , Kusumasari Nila
Published: January 2025

Background: The elderly population has been rapidly increasing over the past few decades. In Indonesia, the percentage of elderly residents is 8.75% of the total population. Aging is an unavoidable process, but it requires care to ensure a good quality of life for the elderly. One of the issues affecting the quality of life in the elderly is skin aging. Skin aging causes various complaints, especially itching or pruritus, which can reduce the quality of life for the elderly. Knowledge of the pathophysiology of skin diseases and skin aging, as well as the factors that affect them, particularly skin hydration, is necessary. This research is expected to be beneficial for medical professionals as well as family members of the elderly. The elderly residents at Wreda Griya PMI Peduli and Aisyiyah Nursing Home come from various regions and economic backgrounds. Therefore, the researchers consider the nursing home to be an appropriate place to conduct this study, as it can represent the elderly population from diverse backgrounds across Indonesia.Objective: This study aims to analyze the various skin disease profiles at the Griya PMI Peduli and Aisyiyah nursing homes in the city of Surakarta. Methods: This type of research is a survey using an observational study method with a descriptive design. Results: There were a total of 45 subjects at the Wreda PMI Peduli and Aisyiyah Nursing Home in Surakarta. Among them, 34 subjects had skin complaints, while 11 subjects were excluded because they did not have any skin complaints (7 subjects) or were uncooperative (4 subjects). The most common diagnosis was xerosis cutis (53%). The majority of patients did not have comorbidities (65%), with the most common comorbidity being hypertension (26%). Conclusion: The results of this study indicate that all the main skin complaints among the elderly at Panti Wreda in Kota Surakarta were dominated by itching or pruritus, with xerosis cutis being the primary etiology of pruritus in the elderly subjects of the study, accounting for 53%.
The relationship between different ventricular rate control levels and cardiac remodeling in early persistent atrial fibrillation: a prospective cohort study
Authors: Liu Yongrong , Liu Jun , Wang Dan
Published: January 2025

Background

Atrial fibrillation (AF) is a prevalent cardiac arrhythmia, with ventricular rate control being a critical therapeutic target. However, the optimal range for ventricular rate control remains unclear. Additionally, the relationship between different levels of ventricular rate control and cardiac remodeling in patients with atrial fibrillation remains unclear.

Objective

This study aims to explore the relationship between different levels of heart rate control and cardiac remodeling in patients with early persistent atrial fibrillation.

Methods

A bi-center prospective cohort study was conducted, enrolling patients with newly diagnosed persistent AF and rapid ventricular rates, yet with a normal cardiac size, from March 2019–May 2020 at the people's hospital of Chongqing Hechuan and the First Affiliated Hospital of Zhengzhou University. Patients were divided into four groups based on their average ventricular rate levels from 24 h Holter monitoring: Group I (40 ≤ average rate < 60 bpm), Group II (60 ≤ average rate <80 bpm), Group III (80 ≤ average rate < 100 bpm), and Group IV (average rate ≥ 100 bpm).The study tracked changes in left atrial diameter (LAD), left ventricular end-diastolic diameter(LVEDD),left ventricular ejection fraction(LVEF), and the severity of mitral regurgitation over one year.

Results

A total of 764 patients were enrolled. We found that there were no significant differences in cardiac remodeling among the groups of patients before the observation. However, after one-year follow-up observation, there were significant differences in the degree of cardiac remodeling among the groups (p < 0.001). Specifically, the severity of cardiac remodeling, including LVEDD, LAD, LVEF, and mitral regurgitation, showed the following trend: Group II < Group I < Group III < Group IV. Further regression analysis indicated that body mass index (BMI) might be related to changes in LAD. Additionally, the use of digoxin could affect changes in left ventricular ejection fraction. At the same time, the use of diltiazem, bisoprolol, as well as factors like hypertension, coronary artery disease, smoking, diabetes, and chronic obstructive pulmonary disease, might be closely associated with the worsening of mitral regurgitation.

Conclusion

This study shows that in early persistent AF patients, different levels of heart rate control are related to varying degrees of cardiac remodeling. These results suggest that maintaining an average ventricular rate within the range of 60–80 beats per minute may be associated with milder cardiac remodeling. On the other hand, an average heart rate greater than 100 bpm appears to be associated with the most severe cardiac remodeling.

Registration Number

ChiCTR2400079978; Registered 17 January 2024–Retrospectively registered: https://www.chictr.org.cn/showproj.html?proj=198684.
Therapeutic potential and pharmacological insights of total glucosides of paeony in dermatologic diseases: a comprehensive review
Authors: Wang Huige , Yu Wenchao , Wang Tong , Fang Dianwei , Wang Zeyun , Wang Yuanhong
Published: January 2025

Total glucosides of paeony (TGP) are a group of monoterpenes extracted from Paeonia lactiflora Pall., primarily including metabolites such as paeoniflorin and oxypaeoniflorin. Modern pharmacological studies have shown that TGP possesses a variety of biological effects, including immunomodulatory, anti-inflammatory, hepatoprotective, nephroprotective, antidepressant, and cell proliferation regulatory activities. In recent years, clinical research has demonstrated favorable therapeutic effects of TGP on disorders of the liver, cardiovascular, nervous, endocrine, and skeletal systems. Particularly in dermatological treatments, TGP has been found to significantly improve clinical symptoms and shorten the course of the disease. However, there are still certain limitations in the scientific rigor of existing studies and in its clinical application. To assess the potential of TGP in treating dermatologic diseases, this article provides a review of its botanical sources, preparation and extraction processes, quality control, and major chemical metabolites, as well as its pharmacological research and clinical applications in dermatology. Additionally, the mechanisms of action, research gaps, and future directions for TGP in the treatment of dermatologic diseases are discussed, offering valuable guidance for future clinical research on TGP in dermatology.
Digital business, work and consumption in a service relation: a case study of a delivery platform company
Authors: Cruz Sofia Alexandra , Sales Oliveira Catarina
Published: January 2025

The platform economy has contributed to new ways of organising business, work, and consumption. To understand the shape and scope of these changes, it is crucial to pay simultaneous attention to these three domains. The new ways of organising, dividing and coordinating work are interlinked with specific ways of consuming services made available by digital platforms. This article analyses a case study of a delivery platform company with a specific business model marked by strong territorial roots and promoting relational proximity between the platform, workers, and clients. It proposes an approach to the service relation between the platform, workers, and clients allowing to explore institutional, intersubjective and spatial–temporal dimensions that shape it. Intersubjective, because they point to particular modes of communication and involvement between the parties. Institutional, as the platform reflects the organisational environments within which it operates. Spatio-temporal, as this service relation promotes flexible spatial and temporal arrangement that articulates various urban actors.
Optimal Multi-Physics Synthesis of a Dual-Frequency Power Inductor Using Deep Neural Networks and Gaussian Process Regression
Authors: Di Barba Paolo , Ghafoorinejad Arash , Mognaschi Maria Evelina , Dughiero Fabrizio , Forzan Michele , Sieni Elisabetta
Published: January 2025

In this paper, a multi-physics case study belonging to the class of induction heating problem is considered. Finite Element Analysis is used to evaluate the temperature along a line on a graphite disk heated by two power inductors. In order to build a surrogate field model of the device, i.e., to compute the temperature profile on the disk, given the amplitudes and frequencies of the supply currents, three methods have been used (Support Vector Regression (SVR), fully connected Neural Network (NN) and Gaussian Process Regression (GPR)). In turn, to solve the inverse problem, i.e., to identify frequencies and currents of the two coils, given a prescribed temperature profile, two approaches have been implemented. The former is an optimization approach based on a multi-objective formulation, solved by means of the NSGA-II algorithm; the latter is a two-step procedure, based on fully connected Deep Neural Networks (DNNs), solving an optimal design problem first and, subsequently, an optimal control problem.
Anomaly Detection and Root Cause Analysis for Energy Consumption of Medium and Heavy Plate: A Novel Method Based on Bayesian Neural Network with Adam Variational Inference
Authors: Guo Qiang , Li Fenghe , Liu Hengwen , Guo Jin
Published: January 2025

Anomaly detection and root cause analysis of energy consumption not only optimize energy use and improve equipment reliability but also contribute to green and low-carbon development. This paper proposes a comprehensive diagnostic framework for detecting anomalies, conducting causal analysis, and tracing root causes of energy consumption in medium and heavy plate manufacturing, integrating process mechanisms, expert knowledge, and industrial big data. First, a two-stage anomaly detection method based on box plot analysis is developed to identify energy consumption irregularities. Next, a weighted Granger causality analysis method based on LSTM is introduced, which effectively captures the nonlinear and temporal relationships of process variables, enabling the identification of abnormal causal pathways. Finally, a root cause tracing algorithm using an Adam-based variational inference Bayesian neural network is proposed to pinpoint the underlying factors responsible for the anomalies. Experimental results validate the effectiveness of the proposed methods.
Navigating the Complexities of HIV Prevention for Adolescents and Young Persons: A Science-to-Program and Systems Approach
Authors: Dzinamarira Tafadzwa , Moyo Enos , Murewanhema Grant
Published: January 2025

This opinion paper dives into the crucial but challenging space of HIV prevention for adolescents and young persons (AYPs). While their vulnerabilities may be heightened, so too is their potential for resilience, innovation, and positive change. To safeguard their health and empower them to make informed choices, a comprehensive science-to-program and systems approach to HIV prevention is paramount. Recognizing their unique vulnerabilities and immense potential, these authors advocate for a multifaceted approach that bridges the gap between scientific evidence and program implementation within a robust healthcare system. This opinion unpacks how leadership, governance, health policies, human resources, health information systems, and HIV surveillance can be strengthened to create a supportive ecosystem where AYPs have the knowledge, resources, and services they need to thrive. This collective effort, involving policymakers, healthcare providers, educators, and AYPs themselves, is critical to a future where no young person is left behind in the fight against HIV.