bluuebunny/crossref_metadata_2025 huggingface dataset:
Handgebaren in interacties met anderstaligen: een detailanalyse
Authors: Prové Valentijn , Feyaerts Kurt , Oben Bert
Published: May 2023

Foreigner Talk refers to a repertoire of linguistic and non-verbal strategies that a language community regards as appropriate in interactions with less proficient L2 speakers. Such adaptations often include the use of hand gestures, as illustrated by different communication guidelines. However, research on gestures in Foreigner Talk has almost exclusively focused their ability to illustrate concrete actions and objects, limiting our understanding of how more abstract gestures can be helpful in interactions with L2 speakers. In this paper, we propose a qualitative analysis of gestures in four excerpts from a corpus of semi-spontaneous conversations between L1 and L2 speakers and we highlight gestures that motivate their meaning at different degrees of abstraction.
Non-EFL students’ perspectives on English learning in higher education institution: The case of Indonesian non-English major
Authors: Putra Rizky Anugrah , Suparni Suparni
Published: May 2023

The annulment of English subject at the elementary and tertiary levels harms the absorption of graduates. This decision needs to be reviewed whether it follows current conditions where graduates are required to be able to compete globally. Competition becomes increasingly problematic because students lack continuous English learning. This study aims to reveal the perspectives of non-EFL students on learning English in their faculties and how the association between English learning achievement scores and their perspectives on the language they are learning is related. It involved 45 students from two non-English faculties who studied English only as a general course. Our statistical calculations using correlation analysis found that most non-EFL students had an optimistic viewpoint on English and hoped to be provided with it continuously. In addition, the analysis also found that the achievement scores in English lessons had a significant positive correlation with their perspectives.
Tailoring EFL lessons through materials adaptation: A look into an Acehnese teacher’s experiences
Authors: Hanifa Rizaldy , Yusra Siti Rahimah
Published: May 2023

This study focused on teachers’ materials adaptation as a part of teaching strategies to ensure learning success. Given that such activity is not something light to engage in and requires expertise, the researchers looked at how the process of materials adaptation was carried out. These included what was added, removed, and modified as well as the challenges confronted during the adaptation process and classroom implementation. This study sought perspective from a qualitative case study approach. Documents, classroom observations, and interview were employed to gather data from one senior high school teacher in Aceh, Indonesia. The results were analyzed based on frameworks of language teaching materials analysis, principles of teaching materials, and materials adaptation. Research findings suggested that materials adaptations mostly concentrated on adding and modifying, with less emphasis on eliminating, simplifying, and rearranging. Furthermore, the altered materials aided language learning in various ways. Nevertheless, several modifications made raised issues, such as the lack of a feeling-sharing session with the materials and an inappropriate difficulty level. Inaccessible sources of materials, fear of producing irrelevant information, time constraints, a lack of professional training and school assistance, learners’ uncooperative behavior and low competences were also identified as problems in materials adaption.
The integration of intercultural communicative competence in ELT settings: A systematic review
Authors: Permatasari Indah
Published: May 2023

Intercultural communicative competence, commonly known as ICC, refers to the ability to respectfully compare and mediate between different cultural values. This study aims to systematically review the current trends and main findings of the studies focusing on the integration of ICC in ELT settings. A total of 17 peer-reviewed articles published between 2018 and 2022 were analysed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) items. The results showed that there has been a fluctuation in the number of studies published during the last four years. From the reviewed articles, it was found that most of the studies were conducted in Asia and used a qualitative method in examining the higher education students’ skills and perspectives on ICC. Additionally, it was reported that using intercultural teaching and learning practices was effective in improving the participants’ ICC. Nonetheless, many studies found it difficult to implement intercultural teaching and learning practices, particularly when it came to time constraints, learning material availability, and establishing success criteria. This underlines the necessity of creating a comprehensive instructional learning model that can help ESL and EFL teachers, as well as other educational practitioners, integrate ICC.
The effectiveness of using multiple intelligence activities in listening comprehension and improving students' interest
Authors: Alilateh Atikah , Widyantoro Agus
Published: May 2023

This study aims to find out (1) the effectiveness difference between the use of multiple intelligence activities and the conventional activities in listening comprehension, and in the students’ interest in learning English. This study used the quantitative method. The study design was quasi- experimental with the pre-test and the post-test group design. The experimental class used 5 categories of multiple intelligences namely; linguistic intelligence, logical/mathematical intelligence, visual intelligence, musical intelligence, and naturalist intelligence. This study used a listening comprehension test and a questionnaire as the research instruments for collecting the data. The technique of the data analysis in this study was MANOVA. The result shows that: (1) the use of multiple intelligence in listening comprehension is more effective than the conventional activities with sig 0.000; (2) the use of multiple intelligence activities in students’ interest in learning English is more effective than the conventional activities with sig 0.000.
Interferensi sintaksis Bahasa Indonesia dalam Abstrak Prosiding ICOBAME 2018
Authors: Pratiwi Berlin Insan
Published: May 2023

Penelitian ini dilakukan dengan tujuan menemukan bentuk interferensi sintaksis yang terdapat pada prosiding International Conference on Banking, Accounting, Management, and Economics (ICOBAME) 2018. Peneli-tian ini merupakan penelitian deskriptif. Desain yang digunakan dalam penelitian ini adalah desain penelitian kualitatif dan jenis penelitian analisis isi. Terdapat 13 bentuk interferensi sintaksis yang terjadi dalam objek penelitian yang terdiri dari 8 bentuk interferensi dalam tataran frasa, 4 bentuk interferensi dalam tataran klausa, dan 7 bentuk interferensi dalam tataran kalimat. Wujud perbedaan paling mendasar antara bahasa Indonesia dan bahasa Inggris, yaitu kaidah DM-MD, terealisasi dalam objek penelitian. Ditemukan data yang menunjukkan interferensi kaidah DM terhadap perwujudan yang seharusnya MD. Selain itu perbedaan tata bahasa yang lain yang terwujud dalam objek penelitian adalah bentuk-bentuk interferensi yang disebabkan oleh ketidaktepatan penggunaan preposisi, ketidaktepatan penggunaan definitive word, ketidaktepatan pemilihan kata dan kelas kata, ketidaktepatan penggunaan kata ‘no’ dan ‘not’, ketidaktepatan subject-verb agreement, ketidaktepatan penggunaan v-ing, ketidaktepatan bentuk paralelisasi, serta ketidaktepatan bentuk kata yang dipengaruhi kala dan penjamakan. Indonesian syntaxis interference of the ICOBAME 2018 Proceeding abstracts AbstractThis research was conducted with the aim of finding the syntaxis interference in the proceeding of the International Conference on Banking, Accounting, Management, and Economics (ICOBAME) 2018. This research was descriptive research. The design employed in this study was qualitative research design specifically content analysis. There were 13 syntaxis interference forms occur in the object of research consisting of 8 forms in phrasal level, 4 forms in clause level, and 7 forms in sentence level. The fundamental difference between Indonesian and English, that is the DM-MD rules, was barely anticipated. Other grammatical differences manifested in the research object were syntaxis interference caused by the inaccurate use of prepositions, inaccurate use of definitive words, inaccurate choice of words and class of words, inaccurate use of 'no' and 'not', inaccurate use of the subject-verb agreement, inaccurate use of v-ing, inaccurate forms of parallelization, and inaccurate use of word choice depending on the tense and pluralization.
Graduate students’ attitudes & self-directed for lifelong learning in foreign language environment
Authors: Sari Desy Mutia , Ashadi Ashadi
Published: May 2023

The student’s attitude is needed to be self-directed learners to maintain lifelong learning in the ever-changing world. Thus, this study aimed to reveal whether graduate students’ self-directed skills and attitudes vary based on university type and gender. Also, this study explored the relationship between graduate students’ attitudes and self-directed lifelong learning skills then, further identified the lowest attitudes predictors for SDL, and analyzed how the students perceive the lecturer’s role in self-directed learning. In a mixed-method study, 92 students from two selected public universities took questionnaires to measure their attitudes and self-directed learning and four students involved in the semi-structured interview. The obtained results showed that SDL and attitudes were found not to vary based on the university type. However, gender made a significant difference in SDL in favour of female students. Then, attitudes variable statistically significantly predicted students’ SDL and perceptions of confidence and ability that emerged as the attitude dimension, seemed to be the lowest associated with the students’ SDL. The majority of the students are still unaware of the SDL behaviour and see the lecturer as a factor that decisively affects them in developing greater independence. Further theoretical and practical implications are discussed.
The effectiveness of project-based learning to teach writing in relation to students’ creativity
Authors: Soffiany Nur Kartika , Purbani Widiastuti
Published: May 2023

This research was aimed to find out whether: (1) the use of project-based learning is more effective than direct instruction in the teaching of writing skills; (2) the students having high creativity have better writing skills than those having low creativity; (3) there is a correlation between teaching methods and creativity in teaching writing. This quasi-experimental research was conducted at SMP N 1 Yogyakarta in the academic year of 2016/ 2017. The sample was taken by using cluster random sampling. To collect the data, two instruments were employed. The data were analyzed by Multifactor Analysis of Variance ANOVA 2x2 and Tukey Test by IBM SPSS 22. The findings of this research can be stated as follow: (1) Project-Based Learning is more effective than direct instruction in teaching writing and it is indicated by the value of sig. (0.048); (2) the students who have high creativity have better writing achievement than the achievement of those who have low creativity and it is indicated by the value of sig. (0.000); (3) there is an interaction between teaching methods and students’ creativity in teaching writing and it is indicated by the value of sig. (0.033). It means that the effect of methods and writing skills depends on the level of creativity of the students.
The translation quality of speech acts on the label of product packaging
Authors: Setyowati Lilis , Nababan Mangatur
Published: May 2023

The translation of speech acts on product packaging labels was the object of this research. This study aimed to analyze the types of speech acts, translation techniques used by translators to translate label text, and to identify how these techniques affected changing speech acts on product packaging labels. A qualitative descriptive approach was used in this study. The data was presented in the form of utterances on packaging labels that included speech acts and their translations. Document analysis and focus group discussion were used to gather the data. According to the findings, the researcher discovered 94 different forms of speech acts. The translator used 14 different translation techniques in translating the label. Several translation techniques used in this study affect the changing of speech acts in the target language. Deletion, reduction, modulation, paraphrase, and compensation techniques were found to induce a change in speech acts. There were 12 data of the speech acts shifting. The cumulative score for the quality of the translation on the product packaging label was 2.75.
The effectiveness of edmodo and schoology in descriptive writing for Universitas Muhammadiyah Yogyakarta students
Authors: Oktaviani Rizki Dwi , Widyantoro Agus
Published: May 2023

This research was aimed to figure out (1) the students’ achievement in descriptive writing taught by using Edmodo and Schoology, (2) the differences of students’ achievement in descriptive writing taught by using Edmodo, Schoology, and the conventional media, and (3) the most effective media among the media compared in descriptive writing for the students of Yogyakarta Muhammadiyah University. This research was a quasi-experiment study with a nonequivalent (pretest and posttest) control group design. The data were collected through written tests. The reliability of the instruments was gained using inter-rater reliability. The data were analyzed using the covariant analysis (ANCOVA) and the Scheffe test. The results of the study showed that: (1) the use of Edmodo and Schoology gave a positive contribution to students’ achievement in descriptive writing, (2) there were differences among students’ achievement in descriptive writing taught by using Edmodo, Schoology and the conventional media, (3) the use of Edmodo and Schoology was more effective than the conventional media.
Ideologi perlawanan dalam bahasa humor politik pada buku Republik Badut karya Darminto M. Sudarmo
Authors: Ameliya Rizqi , Sayuti Suminto A
Published: May 2023

Penelitian ini bertujuan untuk mengungkap: (1) konstruksi teks humor; (2) konstruksi wacana perlawanan; (3) ideologi yang tersembunyi dalam wacana humor politik pada buku Republik Badut karya Darminto M. Sudarmo. Penelitian ini merupakan penelitian kualitatif dengan paradigma kritis. Teknik analisis data dalam penelitian ini menggunakan analisis tiga dimensi Norman Fairclough: (1) analisis teks, (2) analisis discourse practice, (3) analisis sosiocultural discourse. Hasil penelitian yang diperoleh menunjukkan bahwa: (1) konstruksi teks humor dalam buku Republik Badut karya Darminto M. Sudarmo cenderung menggambarkan Republik Badut sebagai analogi dari Republik Indonesia, (2) konstruksi wacana perlawanan disampaikan dalam bentuk kritik dan humor yang menyuarakan perlawanan terhadap ketidakadilan, ketimpangan, dan kecurangan yang dilakukan para elit penguasa terhadap rakyat, dan (3) Ideologi perlawanan yang disuarakan Darminto M. Sudarmo dalam buku Republik Badut, yakni: a) perlawanan teradap kejahatan atau kecurangan (korupsi), b) perlawanan terhadap elit penguasa, c) perlawanan terhadap tindak represif, d) perlawanan terhadap retorika para politisi, e) perlawanan terhadap pencitraan presiden, f) dan penyatuan gagasan senasib sepenanggungan dari kaum proletar. Rebellion ideology of political humour language in Darminto M. Sudarmo’s Republik Badut Abstract: The research aims to reveal: (1) the constructed text humour, (2) the constructed rebellion discourse, (3) the hidden ideology in political humour discourse in Darminto M. Sudarmo’s Republik Badut. This research was qualitative with the critical paradigm. The data were collected through Norman Fairclough three-dimensional analysis: (1) text analysis, (2) the analysis of discourse practices, (3) sociocultural discourse analysis. The research results show that: (1) the construction of the text humour in Darminto M. Sudarmos’s Republik Badut tend to depict Republik Badut as an analogy of the Republic of Indonesia, (2) the construction rebellion discourse delivered in the criticism and humour were submitted rebellion to injustice, inequality, and the fraud by the government to the people, (3) the rebellion ideology of Darminto M. Sudarmo’s Republik Badut convey: a) rebellion against crime and corruption, b) rebellion against the government, c) rebellion against repressive acts, d) rebellion against the rhetoric of politicians, e) rebellion against president’s self-image, f) and ideas-unity among ordinary people to live in the same boat.
Korean wave’s influences on Indonesian beauty standard depicted in skincare advertisements: Critical discourse analysis
Authors: Pramusita Santa Maya
Published: May 2023

This research aims to disclose the influence of the Korean wave toward the Indonesian beauty standards reflected in the skincare advertisements. A descriptive qualitative method with the approach of critical discourse analysis is employed to obtain the research objective. The media are Viva moisturizer advertisement appeared in the early 2000s, Wardah White Treatment Essence advertisement published in 2019, and Laneige BB Cushion Korean advertisement as a part of intertextuality. The 19 year-publication gaps is deliberately presented to show how the shift of beauty myth takes place. The data taken were in words, phrases, and sentences, which were then analyzed using Fairclough's three-dimensional approach. The results showed that Viva attracted consumers’ attention using similes, simple present tense, keywords repetition, and positive adjectives. On the other side, Wardah used hyperbole, possessive pronoun, and scientific terminology to convince the consumers of their product’s superiority, in line with Laneige's advertisement. Regarding the discursive features, these three advertisements were similar in that they used logos, flattery, puffery, and positive image representation. Lastly, the analysis of social practice indicated that the influence of the Korean wave was clearly seen on Wardah’s commercial, which portrayed beauty as Laneige did. They tried shaping consumers’ beliefs that beauty means having a white, flawless, and glowing face. Thus, the beauty myth had changed from the previous era. This resembles Bourdieu’s notion of field, capital, and Doxa.
Critical discourse analysis of all will be fine by Buju Banton: An inspirational song
Authors: Hasibuan Hapni Nurliana H.D , Triyono Sulis , Sahayu Wening
Published: May 2023

Song lyrics have some purposes, reasons, and messages. It contains various themes such as current and social issues and issues that the songwriter wants to share through the ideology, thoughts and feelings expressions. This research aims at finding out the text analysis, social cognition and social context of the All Will Be Fine song. The research used a qualitative research design. The key instrument of the research is human instrument. In validating the data, this research used the triangulation technique. Further, the data were analyzed using Van Djik’s analysis model. It was analyzed through the dimensions of text (macrostructure, superstructure, and microstructure), social cognition and social context. The research used Agih method to analyze three stages of text dimensions and Padan method to determine the social cognition and social context of the song lyric. Based on the analysis that has been done, the results provided that the words of discourse were cohesive, coherent and communicative. In addition, the social cognition diction of the song lyrics has been relatable to the current condition and Covid-19 all around the world as social context.
Pre-service English teachers’ practices of designing and implementing lesson plans for teaching practicum
Authors: Lestari Anes Eka , Lestari Sri
Published: May 2023

It is consequential for pre-service English teachers to be able to construct lesson plans as well as to implement those plans in the classroom. Such skills will help them teach more effectively when they become English teachers in the future. This study aims to investigate pre-service English teachers’ practices in developing lesson plans for their teaching practicum during the pandemic. Employing a qualitative approach, the data were collected from document analyses and interviews involving students majoring in English Education who had completed their teaching practicum at a private junior high school. The findings revealed that the implemented activities in the English teaching practicum were mostly consistent with the lesson plans. This study also found that, despite the general consistency, the pre-service English teachers struggled to develop their lesson plans as they had to adjust the number of activities with the reduced time allotment due to the pandemic. In conclusion, the pre-service English teachers in this study were able to create lesson plans adapting to the limited duration of the English sessions for the practicum during the pandemic, but they were still unable to implement all the activities written on the plans due to the constraints of time and classroom management skills.
Divergensi modalitas Charles J. Fillmore dalam novel terjemah "Sayap-Sayap Patah" karya Kahlil Gibran
Authors: Fatmawati Fatmawati , Zaini Hisyam , Ngarifah Imroatul
Published: May 2023

Penelitian ini bertujuan untuk menganalisis bentuk-bentuk divergensi modalitas dari Charles J. Fillmore dan maknanya dalam novel terjemahan “Sayap-Sayap Patah” karya Kahlil Gibran agar terhindar dari kesalahpahaman dalam memaknai bahasanya. Jenis penelitian ini adalah penelitian kualitatif deskriptif. Sumber data primernya adalah terjemahan novel “Sayap-Sayap Patah”, sedangkan sumber data sekundernya adalah referensi yang mendukung sumber data primer, yaitu buku-buku semantik khususnya tentang teori tata bahasa kasus Charles J. Fillmore. Dalam pengumpulan data, peneliti menggunakan teknik baca-catat. Dari penelitian ini dapat diketahui bahwasanya dalam terjemah novel tersebut terdapat empat bentuk modalitas yaitu (1) intensional, yang memiliki makna keinginan, harapan, ajakan, pembiaran, dan permintaan; (2) epistemik, yang terdiri dari makna kemungkinan, keteramalan, keharusan dan kepastian; (3) deontik, yang bermakna perintah; dan (4) dinamik, yang bermakna kemampuan. Berdasarkan hasil terebut dapat diketahui bahwa novel terjemah “Sayap-Sayap Patah” menggunakan modalitas yang kompleks, akan tetapi lebih banyak menggunakan modalitas intensional. Tokoh yang tercermin dalam karya sastra ini cenderung tidak memiliki sifat otoriter, melainkan demokratis.This study analyses Fillmore's modality variances and their meaning in the Indonesian translation of the novel “Broken Wings” by Kahlil Gibran. This is a descriptive qualitative research. The translated novel, “Sayap-Sayap Patah” is the primary data while the secondary data are taken from the literature on the semantic theory of Charles J. Fillmore. The researchers used the close reading technique to collect the data. From this research, it can be inferred that in the Indonesian translation of the novel, there are four forms of modalities namely (1) intentional modality, which conveys desire, hope, invitation, neglect, and request; (2) epistemic modality, which deals with the ideas of possibility, practicality, necessity, and certainty; (3) deontic modality, meaning commands; and (4) dynamic modality, which concerns the idea of abilities. These results indicate that the Indonesian translation of the novel “Broken Wings” uses complex modalities with the majority being intentional modalities. The main character reflected in this novel tends not to have an authoritarian nature but a democratic one.
Minimal residual disease in acute leukemia based on the insight of molecular genetics monitoring
Authors:   Department of Biology, College of Science, University of Jeddah, Jeddah 21493, Saudi Arabia, Alyamani Najiah M.
Published: May 2023

Patients with acute leukemia port 10 malignant cells at presentation. Following chemotherapy or stem cell transplant, patients in complete remission by conventional analyses may still harbor 106/108 malignant cells below the detection limit of standard clinical assessment. Minimal residual disease (MRD) monitoring is one of the most powerful predictors of disease-free and overall survival, particularly for children with acute lymphoblastic leukemia (cALL), the percent annual of cALL increase in the incidence of cALL in Saudi Arabia. Breakpoint fusion regions of chromosomal aberrations can be used as tumor-specific targets for MRD detection by polymerase chain reaction. Levels of MRD, measured at critical time points, significantly correlate with clinical outcomes. Previous works investigated the prognostic significance of leukemia-associated immunophenotypes (LAIPs) as an assessment of the index of MRD in 125 adult B-ALL patients by eight-colour flow cytometry. More advanced molecular and genetics studies are so necessary to identify the mechanisms and cellular structure of the minimal-level disease. Selecting molecular methods for minimal residual disease detection have a much higher sensitivity and precision (100-fold or more) than others. This review highlights the minimal residual disease molecular detection to demonstrate the characterization of the lymphoblastic leukemia gene. Precise MRD monitoring predicts disease relapse after chemotherapy or SCT, provides early intervention, and may result in the rescue of many patients and improvement in the probability of long-term disease-free survival.
Recomendaciones tecnológicas para el mejoramiento del sistema productivo de caña de azucar para panela en el occidente de Nariño
Authors: Díaz Montilla Ana Elizabeth , Peñaranda Rolón Andrea María , Benavides Cardona Carlos Andrés , Espinel Correal Carlos , González Chavarro Carlos Felipe , Serralde Ordóñez Diana Paola , Lagos Burbano Elizabeth , Igua Urbano Erika Paola , Rodríguez Borray Gonzalo Alfredo , Gavilanes Bravo Jacqueline Lucia , Rodríguez Cortina Jader , Ángel Juan Carlos , Cardona Iglesias Juan Leonardo , Romero Juan Vicente , Ramírez Durán Julio , España Pantoja Lucio Exequiel , Narváez Morales Luis Hernando , Prada Forero Luz Esperanza , Murcia Pardo Magda Liliana , Ramírez Gómez María Margarita , Polo-Murcia Sonia Mercedes , Quevedo Amaya Yeison Mauricio
Published: May 2023

El manual, resultado del proyecto, está dirigido, principalmente, a los productores de caña de azúcar para panela y los trapicheros de la región occidente, a los asistentes técnicos y a todos aquellos actores interesados en el cultivo de la caña de azúcar para panela y su agroindustria. Con un lenguaje sencillo, se desarrollan los principales temas de interés para el sector panelero de Nariño: la caracterización socioeconómica, el manejo agronómico de la caña, el proceso para obtención de panela y los costos de producción. Con el fin de fortalecer la cadena productiva, hacer más atractivo el campo a la población de jóvenes agricultores y contribuir al relevo generacional necesario para la sostenibilidad y competitividad del campo, se espera que estas recomendaciones aporten a la reconversión y modernización tecnológica del subsector panelero del departamento.
Misinformation and Public Health Messaging in the Early Stages of the Mpox Outbreak: Mapping the Twitter Narrative With Deep Learning
Authors: Edinger Andy , Valdez Danny , Walsh-Buhi Eric , Trueblood Jennifer S , Lorenzo-Luaces Lorenzo , Rutter Lauren A , Bollen Johan
Published: May 2023

Background

Shortly after the worst of the COVID-19 pandemic, an outbreak of mpox introduced another critical public health emergency. Like the COVID-19 pandemic, the mpox outbreak was characterized by a rising prevalence of public health misinformation on social media, through which many US adults receive and engage with news. Digital misinformation continues to challenge the efforts of public health officials in providing accurate and timely information to the public. We examine the evolving topic distributions of social media narratives during the mpox outbreak to map the tension between rapidly diffusing misinformation and public health communication.

Objective

This study aims to observe topical themes occurring in a large-scale collection of tweets about mpox using deep learning.

Methods

We leveraged a data set comprised of all mpox-related tweets that were posted between May 7, 2022, and July 23, 2022. We then applied Sentence Bidirectional Encoder Representations From Transformers (S-BERT) to the content of each tweet to generate a representation of its content in high-dimensional vector space, where semantically similar tweets will be located closely together. We projected the set of tweet embeddings to a 2D map by applying principal component analysis and Uniform Manifold Approximation Projection (UMAP). Finally, we group these data points into 7 topical clusters using k-means clustering and analyze each cluster to determine its dominant topics. We analyze the prevalence of each cluster over time to evaluate longitudinal thematic changes.

Results

Our deep-learning pipeline revealed 7 distinct clusters of content: (1) cynicism, (2) exasperation, (3) COVID-19, (4) men who have sex with men, (5) case reports, (6) vaccination, and (7) World Health Organization (WHO). Clusters that largely communicated erroneous or irrelevant information began earlier and grew faster, reaching a wider audience than later communications by official instances and health officials.

Conclusions

Within a few weeks of the first reported mpox cases, an avalanche of mostly false, misleading, irrelevant, or damaging information started to circulate on social media. Official institutions, including the WHO, acted promptly, providing case reports and accurate information within weeks, but were overshadowed by rapidly spreading social media chatter. Our results point to the need for real-time monitoring of social media content to optimize responses to public health emergencies.
De fronteras, documentos y experiencias de movilidad laboral entre México-Guatemala / Borders, documents and labor mobility experience in the Mexico-Guatemala región
Authors: Velasco Ortiz Laura
Published: May 2023

El propósito del presente artículo es comprender el efecto de las políticas de control fronterizo —centradas en la documentación migratoria— sobre la experiencia de la movilidad laboral transfronteriza en el estado de Chiapas, México, a través de una investigación cualitativa en la localidad de Frontera Comalapa. El análisis de los resultados señala la existencia de una zona libre, donde el estatus migratorio aún parece tener una influencia incipiente en la calidad de la experiencia del cruce fronterizo entre la población guatemalteca que cruza constantemente y en la inserción e integración laboral, a la inversa de lo que sucede con el tránsito hacia el norte de México y Estados Unidos de América, donde hay una mayor vigilancia del Estado.Abstract: The aim of this article is to understand the effect of border control policies —focused on migrant documentation— on the experience of cross-border labor migration in the state of Chiapas, Mexico, through a qualitative research at the town of Frontera Comalapa. The analysis of the results indicates the existence of a free zone, where the migratory status still seems to have an incipient influence on the quality of the border crossing experience and in the labor integration process; the reverse of what happens with the transit to the north of Mexico and the United States, where there is greater surveillance by the State.Keywords: borders; identity documentation; transborder labor mobility; immigration status; Mexico-Guatemala border; Guatemalan migration.Résumé : Le but de cet article est de comprendre l’effet des politiques de contrôle aux frontières — axées sur la documentation d’migrate — sur l’expérience de la migration de main-d’oeuvre transfrontalière dans l’État du Chiapas, au Mexique, à travers une enquête qualitative de la ville de Frontera Comalapa. L’analyse des résultats indique l’existence d’une zone franche, où le statut migratoire semble encore avoir une influence naissante sur la qualité de l’expérience de passage des frontières ou en insertion dans l’emploi; l’inverse de ce qui se passe avec le transit vers le nord du Mexique et des États-Unis, où il y a une plus grande surveillance par l’État.Mots-clés : double frontière ; mobilité transfrontalière de la main-d’oeuvre ; documents d’immigration ; frontière Mexique-Guatemala ; migration guatémaltèque.
Control coercitivo social como factor de riesgo de violencia de pareja / Social coercive control as a risk factor for intimate partner violence
Authors: Huerta Mata Rosa María
Published: May 2023

El objetivo de este trabajo es analizar el control coercitivo social como factor de riesgo de violencia en la pareja. Empleando la metodología cualitativa, se investigó el control coercitivo sobre las jóvenes universitarias de la Escuela Superior de Actopan de la Universidad Autónoma del Estado de Hidalgo, en México. En septiembre y octubre de 2017 se llevaron a cabo tres grupos focales de hombres y cuatro de mujeres, donde participaron 48 estudiantes de las licenciaturas en Psicología y Derecho.Se encontró que los hombres despliegan control coercitivo sobre las jóvenes universitarias cuando ellas interactúan socialmente en el espacio público con otros hombres. Así, día a día se configura el riesgo en la integridad de las mujeres. Lo anterior demanda la necesidad de establecer acciones para desarrollar la empatía entre todas las personas involucradas, como estrategia para generar sensibilidad social en torno a la violencia en la pareja.Abstract: The objective of this paper is to analyze coercive social control as a risk factor in intimate partner violence. Through qualitative methodology, the coercive control of the young university students of the Actopan High School, at the Autonomous University of the State of Hidalgo, Mexico, was investigated. In September and October 2017, 3 focus groups of men and 4 of women were carried out with a total of 48 undergraduate students in Law and Psychology.It was found that men display coercive control over their partners, when the female university students interacted socially in a public place with other men. Thus, day by day the risk in the women’s integrity is configured. This situation demands the need to establish actions for developing empathy among all parts involved, as a strategy for generating social sensitivity surrounding partner violence.Keywords: intimate partner violence; coercive social control; risk factor; female; university students.Résumé : L’objectif de cette étude est d’analyser le contrôle coercitif social comme facteur de risque de violence entre partenaires intimes. Grâce à la méthodologie qualitative, le contrôle coercitif sur les jeunes étudiants universitaires de l’École Actopan, à l’Université autonome de l’État d’Hidalgo, au Mexique, a été étudié. En septembre et octobre 2017, 3 groupes de discussion d’hommes et 4 de femmes ont eu lieu, auxquels ont participé 48 étudiants de licence en psychologie et en droit.Il a été constaté que les hommes exercent un contrôle coercitif sur les étudiantes lorsqu’elles interagissent socialement dans l’espace public avec d’autres hommes. Ainsi, jour après jour, le risque pour l’intégrité des femmes est configuré. Cela exige la nécessité d’établir des actions pour développer l’empathie entre toutes les personnes impliquées, comme stratégie pour générer une sensibilité sociale autour de la violence dans le couple.Mots-clés : violence conjugale ; contrôle coercitif social ; facteur de risque ; femmes ; étudiants universitaires.
Звернення головного редактора
Authors: Zotov Alexey
Published: May 2023

No abstract
Аденокарцинома порожньої кишки при PMS2-асоційованому синдромі Лінча. Огляд літератури та клінічний випадок
Authors: Kropelnytskyi V.O. , Zaivelieva I.I. , Kondratenko B.M.
Published: May 2023

Пухлини тонкої кишки — це рідкісна патологія. За даними українського канцер-реєстру, вони становлять 0,2% усіх злоякісних новоутворень. Аденокарциноми становлять 40,9% усіх пухлин цієї локалізації. Частіше вони виявляються у дванадцятипалій кишці, рідше у здухвинній, і найбільш рідкісна локалізація — порожня кишка (5,9%). Аденокарцинома тонкої кишки може бути пов’язана із синдромом Лінча. Синдром Лінча — гетерогенна патологія, зумовлена гермінальними мутаціями у генах, що кодують білки MMR-системи: MLH1, PMS2, MSH2, MSH6, EPCAM. Частіше при цьому синдромі зустрічаються пухлини колоректальної зони, ендометрія, шлунка, проте рідше можуть виявлятися пухлини багатьох локалізацій, у тому числі тонкої кишки. Залежно від того, у якому саме гені відбулася мутація, прояви синдрому Лінча можуть варіювати. PMS2-асоційовані випадки характеризуються більш старшим віком виникнення пухлин, меншою пенетрантністю, меншою кількістю випадків колоректального раку та раку ендометрія. Це призводить до того, що такі пацієнти не підпадають під класичні клінічні критерії діагностики синдрому Лінча. Усі випадки пухлин при синдромі Лінча характеризуються мікросателітною нестабільністю. Наявність мікросателітної нестабільності впливає на прийняття рішення про післяопераційну тактику лікування. У нашій роботі наведено огляд літератури та клінічний випадок діагностики та лікування аденокарциноми порожньої кишки у пацієнта з PMS2-асоційованим синдромом Лінча. Пропонуємо тестувати усі випадки аденокарцином тонкої кишки на наявність мікросателітної нестабільності.
Перихілярна холангіокарцинома, або пухлина Клацкіна: погляд з точки зору японських рекомендацій
Authors: Rozhkova V.O.
Published: May 2023

Перихілярна холангіокарцинома (пухлина Клацкіна) залишається однією з пухлин, які важко піддаються лікуванню. Основними причинами є розташування в зоні зі складною анатомією і відносна резистентність до хіміопроменевої терапії через біологію пухлин жовчних протоків. Отже, хірургічне втручання є основою радикального лікування, яке дозволяє досягти 5-річної виживаності в 55,4 %, згідно з ретроспективними дослідженнями на великих когортах пацієнтів у Японії. Це одні з найбільш вражаючих результатів у сучасній літературі, тож ми поставили за мету дослідити японський підхід до ведення пацієнтів зі злоякісними новоутвореннями перихілярної зони, проаналізувавши рекомендації The Japanese Society of Hepato-Biliary-Pancreatic Surgery. По-перше, увага приділяється ретельному селекціонуванню пацієнтів і передопераційній підготовці, включно з лікуванням жовтяниці й оцінкою залишкового об’єму печінки. По-друге, хоча близькість пухлини до основних судинних структур у воротах печінки збільшує ризик інвазії, це не виключає можливості хірургічного втручання, але робить його технічно складним. Команда з Університету Нагої (Японія) була першою, хто продемонстрував, що одночасна резекція і реконструкція печінкової артерії та ворітної вени покращують довгострокову виживаність пацієнтів і можуть бути виконані командою досвідчених хірургів з прийнятним рівнем післяопераційної летальності. По-третє, адекватна хіміопроменева терапія доповнює радикальну резекцію і вірогідно покращує виживаність пацієнтів.
FORMULATION OF SODIUM ASCORBYL PHOSPHATE (SAP) INTO O/W NANOEMULSION
Authors: RAHMA HANIFA , SUCIATI TRI
Published: May 2023

Objective: Wrinkles are a natural aging consequence that are most visible on sun-exposed skin, such as the face, neck, hands, and forearms. To meet the demands of the aesthetic market, anti-wrinkle active substances have been produced. Due to its capacity to shield skin from free radicals and promote collagen activity, water-soluble vitamin c has emerged as one of the essential anti-wrinkle options. Vitamin c as an antioxidant, can reduce damage caused by free radicals.
Methods: The aim of this study was to develop a water-soluble vitamin c nanoemulsion, identify the optimum formulation, and do stability tests. The method is to mix the ingredients with the same phase first, then mix the two and stabilize with surfactant. A standard procedure was used to produce the nanoemulsion, with the variation ratio of tween 80 to PEG 400 and glycerin. Then, the research went on to the evaluation involved a physical stability test utilizing centrifugation at 3375 rpm, six cycles of freeze-thaw and a thermal stability test at three distinct temperatures for four weeks.
Results: The results showed that the 10% glycerin increased SAP's solubility in the oil phase. A clear and transparent nanoemulsion with fine physical and thermal stability and globule sizes less than 200 nm was produced by the optimum formula, which contained Tween 80, PEG 40, glycerin, VCO, and phosphate buffer at pH 6 in a ratio of 17:9:10:3:61.
Conclusion: The formulation of Sodium Ascorbyl Phosphate has the good physical, chemical characteristic, and stability properties that makes it acceptable to use it as the primary or supplemental therapy for an anti-wrinkle agent with good efficacy and low side effects.
AN OVERVIEW ON ULTRA DEFORMABLE VESICULAR DRUG DELIVERY SYSTEMS IN TRANSDERMAL DRUG DELIVERY
Authors: POLA KRANTHI KUMAR , KUMAR RADA SANTOSH
Published: May 2023

Transfersomes are emerging carriersin transdermal applications owing to numerous benefits like ease of application, reduction in dose frequency, In this review, we will describe about the penetration mechanism of transfersomes, method to prepare the formulation and characterization of transferosomal formulation, like thin film hydration, vortexing sonication, modified handshaking, suspension homogenization, centrifugation, and ethanol injection apart from these characterizations include, vesicle size, shape zeta potential, in vitro, and in vivo to find out the optimized formulation charactering the transferosomal preparations chemical, physical and miscellaneous properties to meet the ideal requirements of formulation and achieve the grater bioavailability and to attain good stability. These formulations are gaining good importance as Novel Drug Delivery Systems because of their patient compliance, ultra deformable and flexible nature due to the presence of surfactants and other pharmaceutical excipients like cholesterol, phospholipids in the formulation; hence these are known as first-generation liposomes.
DEVELOPMENT, CHARACTERIZATION AND ANTIBACTERIAL PROPERTIES OF SILVER NANOPARTICLES LOADED SODIUM ALGINATE/XANTHAN GUM MICROBEADS FOR DRUG DELIVERY APPLICATIONS
Authors: RAMANA E. VENKATA , NASEEM
Published: May 2023

Objective: The aim of this study is to create pH-responsive drug carriers, which are useful because they have the potential to improve treatment efficacy by controlling the release rate of ofloxacin from the polymer matrix.
Methods: In the first step, silver nanoparticles (Ag NPs) were synthesized from silver nitrate using leaf extract of phyllanthus urinaria L as a reducing agent. In the second step, Ag-NPs-loaded polymeric microbeads were synthesized using sodium alginate (SA) and xanthan gum (XG) for controlled release of ofloxacin (OFLX). The developed microbeads were characterized by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (X-RD), transition electron microscopy (TEM), Selected Area Electron Diffraction (SAED), and scanning electron microscopy (SEM). Swelling and in vitro release studies were performed at pH 2.0 and 7.4 at 37 °C. The in vitro antibacterial activity of microbeads were tested against S. mutans, K. pneumoniae, and B. subtilis. The release kinetics and mechanism were analyzed by fitting the release data into different kinetic models and the korsmeyer-peppas equation.
Results: FTIR confirms the generation of silver nanoparticle and also the generation of polymeric microbeads. SEM studies reveal the developed microbeads are spherical in shape with rough surfaces. TEM studies reveal the size of 20-40 nm. XRD analysis reveals the molecular dispersion of DOX and the presence of silver nanoparticles in the polymeric matrix. Investigations of in vitro release and swelling studies show that the developed microbeads are relatively suitable for intestinal drug delivery because higher release rate was observed at pH 7.4. The developed microbead follows non-Fickian diffusion drug release mechanism. The created samples exhibited antimicrobial activity against S. mutans, K. pneumoniae, and B. subtilis.
Conclusion: The results indicate that microbeads containing OFLX and silver nanoparticles are effective drug-delivery vehicles. A further warrant is required for the use of manufactured microbeads in drug delivery applications.
SPRAY-DRIED CHITOSAN MICROSPHERES FOR SUSTAINED DELIVERY OF TRIFLUOPERAZINE HYDROCHLORIDE: FORMULATION AND IN VITRO EVALUATION
Authors: PARAMBIL ANJU , MAANVIZHI SABA , KUTTALINGAM ARUL , CHITRA VELLAPANDIAN
Published: May 2023

Objective: Sustained release systems have the potential to enhance the therapeutic responses in the long-term management of psychiatric disorders. In the present study, cross-linked microspheres of the antipsychotic drug Trifluoperazine (TFP) were prepared using biodegradable polymer-chitosan and various in vitro evaluations were performed on the prepared microspheres.
Methods: The spray drying technique was used to prepare TFP-loaded chitosan microspheres. Tripolyphosphate (TPP) was incorporated into the chitosan solutions as a cross-linking agent in varying concentrations. Different evaluations like production yield, encapsulation efficiency, drug-polymer compatibility, Scanning Electron Microscopy (SEM), X-ray diffraction studies (XRD), Differential Scanning Colorimetry (DSC), particle size, zeta potential analysis and in vitro drug release studies were performed on the developed formulations.
Results: The formulated microparticles exhibited production yields ranging from 38.51 to 57.21% and had reasonably good encapsulation efficiencies (54.52-78.35%). The drug excipient compatibility was confirmed by Infrared Spectroscopy. All the microspheres showed positive zeta potential with a mean diameter ranging from 1.45-3.61µ. SEM images revealed the formation of spherical particles with indentations on the surface. XRD and DSC studies confirmed the presence of an amorphous form of the drug inside the microspheres. The in vitro release profile of TFP from cross-linked chitosan microspheres was influenced considerably by changing the concentration of polymer and crosslinking agent in the formulation. The drug release from (0.5%) chitosan microspheres reduced from 91% to 79%, when TPP concentration was increased from 10% w/w to 30% w/w. All the formulations clearly showed a burst release of the drug in the initial hours and a subsequent sustained release profile.
Conclusion: The results of this study suggest that TPP crosslinked spray-dried chitosan microparticles could be a promising method for developing a long-acting drug delivery system intended to effectively treat schizophrenia.