bluuebunny/crossref_metadata_2025 huggingface dataset:
Psychiatric Morbidity in Elderly Patients attending OPD of Lumbini Medical College and Teaching Hospital
Authors: Sharma Bhaskkar , Shrestha Rajesh
Published: January 2022

INTRODUCTION: Geriatric psychiatry patients are increasing but enough work has not been done in this area of Nepal. We conducted this study to find out the prevalence of different psychiatric morbidities in elderly population and to find out if there are any age and gender specific differences.
MATERIAL AND METHODS: Medical records of psychiatric patients above 65 years of age visiting outpatient department of Lumbini Medical College and Teaching Hospitalfrom April 1, 2018 to March 31, 2019 were reviewed. Risks of having different psychiatric disorders was estimated using odds ratio.
RESULTS: A total of 300 cases were enrolled in the study. Mean age of the study group was 71.49(SD=6.99). There were more females. Depressive disorderwas the most common diagnosis followed by somatoform disorder, anxiety disorder, dementia and others. Depressive disorder was higher in females and in younger subgroup of the elderly patient.The risk of having dementia was higher in older group.
CONCLUSION: Depressive disorder was the most common psychiatric disorderfollowed by somatoform disorder in elderly patients above 65 years of age. Male patients were more likely to suffer psychiatric disorder as compared to females in this age.
Analgesic Effect of Ethanolic Extract of Seeds and Leaves of Coriandrum Sativum on Swiss Albino Mice
Authors: Yadav Chandrajeet Kumar , Tiwari Poonam , Mehta Roshan , Shrivastava Amit Kumar , Palikhey Anjan
Published: January 2022

INTRODUCTION: Pain has been described by the International Association for the Study of Pain as an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. Although NSAIDS and OPIOIDS are available for the treatment, still pain (chronic) is major problem. The present study was designed to study the analgesic effect of ethanolic extract of Coriandrum sativum using hot plate method and acetic acid induced writhing method in experimental animals (Swiss albino mice).
MATERIAL AND METHODS:The analgesic effect of leaves and seeds of Coriandrum sativum was assessed using hot plate method and acetic acid induced writhing method in Swiss albino mice. The animals were treated with the ethanolic extract of leaves and seeds of Coriandrum sativum orally at two doses of 100, 500 mg/kg body weight after electric heat and acetic acid induced pain in mice.
RESULTS: The study showed that ethanolic extract of leaves and seeds of Coriandrum sativum presented significant (p<0.05) and (p<0.05) analgesic activity in mice simultaneously. The data were analyzed by one-way ANOVA followed by Dunette's multiple comparison test. The results demonstrate that ethanolic extract of leaves and seeds of Coriandrum sativum has got analgesic potential.
CONCLUSION: The results demonstrate that ethanolic extract of leaves and seeds of Coriandrum sativum has got significant analgesic effect.
Increased Serum Ferritin Levels in Type 2 Diabetes Mellitus Patients: A Hospital Based Cross-Sectional Study
Authors: Chaudhari Rajendra Kumar , Niraula Apeksha , Gelal Basanta , Baranwal Jouslin Kishore , Sarraf Deependra Prasad , Maskey Robin , Lamsal Madhab Lamsal
Published: January 2022

INTRODUCTION: Type 2 diabetes mellitus is a metabolic disorder of multiple etiology characterized by chronic hyperglycemia with a derangement in carbohydrate, fat and protein metabolism resulting from defects in insulin secretion and action. Ferritin is a ubiquitous intracellular protein complex that reflects the iron stores of the body. Studies have shown that the increased body iron stores are associated with the development of glucose intolerance often leading to metabolic syndrome and type 2 diabetes (T2DM). The objective of the study was to find out association of serum ferritin level with T2DM and assess the correlation between serum ferritin and HbA1c.
MATERIAL AND METHODS: A hospital based comparative cross-sectional study was conducted in 43 diabetic patients and 42 age and sex matched healthy controls. Fasting blood glucose (FBG), postprandial blood glucose (PBG), Glycated hemoglobin (HbA1c) and serum ferritin were estimated in cobas c311 autoanalyser using standard protocol.
RESULTS: Mean age of healthy control and T2DM were found 54.83 ± 6.48 and 55.95±10.92 years respectively. Mean FBG (mg/dL) (170.41 ± 71.7 v/s 98.38 ± 9.7), PBG (mg/dL) (266.16 ± 110.09 v/s 123.20 ± 17.0), HbA1c (%) (8.17 ± 1.83 v/s 4.9 ± 0.29 and median ferritin (μg/L) 207.90 (138, 306.0) v/s 127.95 (85.75, 210.25) were significantly higher in T2DM compared to the healthy controls. Spearman’s correlation depicted that ferritin level was positively correlated with HbA1c level but the correlation was statistically insignificant.
CONCLUSION: Serum ferritin level was found significantly higher in T2DM compared to healthy age and sex matched controls in our study.
Mental Health of Health Science Students during COVID-19 Pandemic: A Cross-Sectional Study in a Medical College of Nepal
Authors: Mahotra Narayan Bahadur , Kandel Sabita , Gurung Sanyukta , Joshi Bishal , Pant Sagun Ballav , Pradhan Sait
Published: January 2022

INTRODUCTION: Mental health impact of COVID-19 is a well-known entity. Health science students are among the high risk groups for developing mental health issues due to lengthy and rigorous studies they undertake. This study aims to explore the mental health of health science undergraduate students of Maharajgunj Medical Campus, and Maharajgunj Nursing Campus during the COVID pandemic in Nepal.
MATERIAL AND METHODS: A descriptive cross-sectional study was conducted from February 2021 to July 2021 using convenience sampling technique using Nepali version of DASS-21 to undergraduate health science students of Maharajgunj Medical Campus and Maharajgunj Nursing campus.
RESULTS: Out of 164 participants, depression, anxiety and stress was seen in 43%, 33% and 29% respectively. Females showed more depression (47.6%) and anxiety (38.8%) and stress (32%) as compared to males
CONCLUSION:Mental health of health science students is adversely affected during the COVID-19 pandemic.
An Emerging, Neglected and Underestimated Zoonotic Parasitic Ocular Infestation: A Comprehensive Review on Thelaziasis
Authors: Kasarla Rajeshwar Reddy , Adhikari Shristi Raut , Ghimire Kripa , Pathak Laxmi
Published: January 2022

Human thelaziasis is an emerging insect-borne zoonotic ocular parasitic infestation, occur more commonly in rural communities with poor living and low socioeconomic living, and mainly affects the children and old age people, where humans live in close proximity with animals. Human thelaziasis is caused by both Thelazia callipaeda and Thelazia californiensis. T. callipaeda lives under the eye lids, nictitating membranes, orbit, conjunctival sac, lachrymal glands, and lacrimal ducts of cats, dogs, rabbits, horses, cattle, deer, badgers, monkeys, wolves, foxes (definitive hosts) and man being an accidental host. The vectors (intermediate hosts) are non-biting, tear-seeking, diptera flies of family Drosophilidae (fruit flies) Phortica variegata, which feeds on tears of their definitive hosts, including humans. Clinical manifestations include conjunctivitis, lacrimation, itching or pain with foreign body sensation, epiphora, follicular hypertrophy, and less often with severe signs and symptoms such as keratitis, photophobia, ectropion, corneal opacities (due to the migration of worm across the cornea), floaters within the eye chamber leading to visual impairment/blindness. The knowledge and scientific information on human thelaziasis is still unknown or relatively limited to many ophthalmologists and clinicians, and received little attention; hence this comprehensive and systematic review of human thelaziasis, is undertaken to highlight its importance and further research.
Spectrum and Presentation of Urinary Bladder Growth: a Single-Center Retrospective Study
Authors: Paudel Deliya , Regmi Himanshu , Bajracharya Uspal , Shrestha Guna K
Published: January 2022

Introduction: Urinary bladder cancers are heterogeneous diseases consisting of a divergent group of tumors.  Diseases of the urinary bladder, both neoplastic and nonneoplastic contribute to notable mortality and morbidity. Histopathology remains the gold standard of diagnosis. Bladder transurethral resection of the tumor is a therapeutic procedure that ensures the material necessary for histopathological diagnosis because it allows assessment of the degree of differentiation, depth of tumor invasion, parameters useful in the elaboration of diagnosis and prognosis assessment

Material and Methods: All the urinary bladder biopsies submitted in the pathology laboratory during 1 year time period were included in the study.

Results: Among the 51 total cases in the study, the male to female ratio was 4.67:1 with the age group of 22-96 years. Among the study population, 30 (52.7%)  presented with hematuria, 10 (19.2%)  with burning micturition, frequent urination, and lower abdominal pain. In the study, 44 (86%) showed neoplastic lesions while 7(14%) remaining were non-neoplastic lesions. Infiltrative urothelial carcinoma with low and high grades was diagnosed in  23% (12/51)

Conclusions: This study has revealed that neoplastic lesions are more common than non-neoplastic lesions. A great majority of neoplastic lesions are of urothelial origin. Majority of which are invasive urothelial neoplasm. All urothelial neoplasms are more common in males. Cystoscopic studies and biopsies help in the early detection of bladder neoplasms and they form the mainstay of the diagnosis and follow-up.
RECYCLING OF WASTE TIRES FOR BIO CRUDE FUEL PRODUCTION THROUGH A PYROLYSIS SYSTEM
Authors:   Environmental  Engineering  Department,  College of Engineering, Mustansiriyah University, Baghdad, Iraq, A. Khalaf Dunya , N. Aboodi Zaidoon ,   Environmental  Engineering  Department,  College of Engineering, Mustansiriyah University, Baghdad, Iraq, M. Daher Saadi ,   Environmental research center, University of Technology, Baghdad, Iraq
Published: January 2022

Recycling of solid waste is one of the most valuable method which is used in worldwide for integral solid waste management. Waste tires are considered to be a source of energy and valuable chemical products. In this study waste tire samples of mixed types (passenger, truck, and heavy vehicles etc.) were decomposed thermally in a fixed bed reactor made up of stainless steel placed inside an electrical heater. Thermal pyrolysis on tire waste samples with (1-2) cm of particle size was carried out at temperatures of 330 ᵒC, 430ᵒC, 530ᵒC, and 630 ᵒC under Argon flow rate of 0.5 L/min and retention time of 15 min to study the effect of temperature on the distribution of pyrolysis products yield. Three main products were obtained by tire pyrolysis pyro oil, gas, and solid residue. Chemical compositions of pyrolysis oil product were characterized by Gas chromatography mass and Fourier transform infrared spectroscopy analyses, it is a complex mixture of alkane, alkene, cycloalkane, cycloalkane, alcohol, ester, and aromatic compounds which are preferable in fuel. If found that a limonene compound occupies the largest proportion of the oil product which is considered as a more valuable compounds.
LAND USE IN THE BAB AL-MOADHAM AREA
Authors:   Highway and Transportation  Engineering  Department,  College of Engineering, Mustansiriyah University, Baghdad, Iraq, Al-Zahraa H. Majeed Noor , J. Qasim Gofran ,   Highway and Transportation  Engineering  Department,  College of Engineering, Mustansiriyah University, Baghdad, Iraq
Published: January 2022

The Bab al- moadham area is distinguished by the diversity of land uses, and the main objective of this is to study the land uses in the region. To achieve the study objective, the study area is divided into two zones. A conversation mechanism has been adopted to collect data. The data collection included all education centers, state institutions, shopping centers and health centers, and their numbers were 21 educational centers, 10 centers belonging to state institutions, 5 shopping centers, 12 health centers. The use of land for educational purposes is very wide compared to the rest of the types of land uses, and the study area is a non –residential area. The number of daily personal trips for educational use is 51549 between students and employees. Because of this varied use of land in the study area, it is considered a high attraction for trips, which helps this study to create an attraction model for the Bab al-Moadham area.
REMOVAL OF FORMALDEHYDE FROM WASTEWATER AND AIR: REVIWE
Authors:   Environmental  Engineering  Department,  College of Engineering, Mustansiriyah University, Baghdad, Iraq, A.Shamkhi Toka , N.Abas Mohamed ,   Environmental  Engineering  Department,  College of Engineering, Mustansiriyah University, Baghdad, Iraq, E.Sachit Dawood ,   Environmental  Engineering  Department,  College of Engineering, Mustansiriyah University, Baghdad, Iraq
Published: January 2022

Formaldehyde is one of the most widely used and widespread aldehydes, and it has been classified as a toxic chemical and may be carcinogenic. Millions of tons of it are released annually into the environment, whether the environment is internal or external, as it is included in many industries in which it and its products are in direct contact with humans. It became necessary to remove formaldehyde, whether from air or water contaminated with it. The main purpose of preparing this paper is to review previous research in removing formaldehyde from waste water and the air by various methods and techniques, including chemical, biological and physical.
COAGULATION/FLOCCULATION PROCESS FOR OILY WASTEWATER TREATMENT
Authors:   Environmental  Engineering  Department,  College of Engineering, Mustansiriyah University, Baghdad, Iraq, A. Jabbar Hussein , J. Alatabe Mohammed ,   Environmental  Engineering  Department,  College of Engineering, Mustansiriyah University, Baghdad, Iraq
Published: January 2022

Oily wastewater is one of the most dangerous forms of environmental pollution, it is large amount of water that is wasted petrochemical industries, oily waste water contains oil, suspended solids, and dissolved solids. The study investigates the treatment of real oily waste water that was collected from al-Dura refinery (Iraq) /Middle Refineries Company from oil and suspended solid contamination for re-use and environmental consideration using coagulation and flocculation processes. Coagulation /flocculation is a common method used as primary purification processes to oily wastewater treatment due to its usability, performance, and low cost. Coagulation experiments were completed by the Jar Test device. The additives coagulants of ferric sulfate and aluminum sulfate were in a range about (10- 25) ppm, as well as polyelectrolyte- (polyacrylamide) as an additional flocculent in the range (1-4) ppm. The results show that ferric sulfate was more efficient in removing turbidity than Aluminum sulfate under the same conditions, with the best removal of turbidity at dose concentration 20 ppm of Ferric sulfate and a flocculent dose concentration of 3 ppm of polyacrylamide, also with oil content decreasing from 288 ppm to 14.4 ppm and the turbidity removal from 187 to 8.5 NTU.
TEMPERATURE AND HUMIDITY FORECASTING IN IRAQ
Authors:   Environmental  Engineering  Department,  College of Engineering, Mustansiriyah University, Baghdad, Iraq, M. Mohammed Zahraa , A. Khaleefa Seroor ,   Environmental  Engineering  Department,  College of Engineering, Mustansiriyah University, Baghdad, Iraq
Published: January 2022

This review targets predicted the change in temperature and humidity in previous studies. Objectives of the present study establish what is known about moisture and temperature conditions in climate and any measurable shifts in Iraq's mean monthly temperatures over the last few decades are assessed.
Male Writers of Dānměi Literature: An Analysis of Fēitiānyèxiáng
Authors: Wang Aiqing
Published: January 2022

In this paper, I investigate dānměi as a ground-breaking literary genre by means of scrutinising an illustrious male writer pseudonymed Fēitiānyèxiáng, and I propound that his works are exemplary as online writing. As a growing Chinese Internet literature, the female-oriented dānměi genre, aka Boys Love, has attracted legions of heterosexual fangirl producers and consumers as well as a meagre amount of their male counterparts. Among male dānměi writers, who are in an absolute minority, Fēitiānyèxiáng is celebrated for a wide range of innovative themes and magnificent storylines, and his fiction is replete with profound literary and historical allusions and elaborate and meticulous depictions. Furthermore, notwithstanding a non-reversible bipartite dichotomy between seme (top) and uke (bottom) roles, Fēitiānyèxiáng’s writing is not featured by feminisation of uke, which is clichéd characterisation in not only the dānměi subculture, but also classical and modern Chinese literature. More significantly, Fēitiānyèxiáng’s narratives are reality-oriented, addressing adverse circumstances in a real-world context and hence rendering characters more multi-faceted, and he does not circumvent realistic issues or create over-romanticised representation, analogous to his equivalent pseudonymed Nánkāngbáiqǐ.
Report from the Middletown Study: The Gradual Progress of Equality in Middletown: A Tocquevillean Theme Re-examined
Authors: Caplow Theodore
Published: January 2022

“The gradual progress of equality,” wrote Tocqueville in his introduction to the first edition of Democracy in America, “is something fated. The main features of this progress are the following: it is universal and permanent; it is daily passing beyond human control, and every event and every man help it along.” That intentionally sweeping generalization has not been disproven by the events of the ensuing century and a half, and the gradual progress of equality continues to be observable in every modern society. Indeed, we are so much further along in that progress that it is now reasonable to inquire about the end-condition toward which it leads us. Will it be a condition of absolute equality or something quite different?
Commentarie : Déviation ou autre modèle
Authors: Reynaud Jean-Daniel
Published: January 2022

A lire l’excellent article de Martin A. Schain, je souhaite, après avoir rendu hommage à l’étendue de l’information et la qualité de l’analyse qu’il présente, pousser plus loin la question qu’il pose. Il veut montrer en effet que le cas de la France, déviant par rapport au modèle de relations professionnelles caractéristique des économies avancées, permet de mieux comprendre les conditions qui permettent le fonctionnement de ce modèle. Ne pourrait-on soutenir qu’en mettant en lumière que ces conditions sont très particulières (et très restrictives) il montre aussi qu’on a prêté peut-être un peu vite à ce modèle une universalité bien discutable, et que d’autres sont possibles ?
Comment
Authors: Brown Bernard
Published: January 2022

There is one respect in which American democracy differs from both the British and French versions : it has no mass social democratic party. The story is long and complicated, but sufficiently well known so that facile generalizations may be avoided. There was a strong socialist movement in America in the early 20th century ; and at one point it might have succeeded in creating a mass party. But the Democratic party under Woodrow-Wilson captured its social base ; the trade union leaders decided their interests could be better served through the existing system. Has American democracy suffered as a result ? Is there a pressing need for a Labor party — such as the one now led by James Callaghan (to say nothing of Anthony Benn) ; or a Socialist party — like the PS led by Guy Mollet in the past, or the one being torn apart by personality rivalries today ? That would be a difficult case to prove. And what is social democracy anyway ? European socialist parties have abandoned nationalization, and for compelling reasons (let us not bother to explain French exceptionalism). Nor is the recent discovery or invention of autogestion likely to win mass support in America. Autogestion is a vague, undefinable scheme that admittedly does not now exist, and has never existed, anywhere in the world. Samuel Gompers had some choice remarks to make about similar utopian proposals in his day.
A return to the Golden Age of Laissez Faire ?
Authors: Solo Robert A.
Published: January 2022

At the base of event, problem and policy in the American economy today is a deep ideological dilemma. To understand it one must recall that from the days of the founding of the Republic and even earlier. American thought. American policy and formation of American institutions, as Tocqueville knew, were dominated by an ideological liberalism that conceived a world of self-seeking, rational individuals, self-sufficient, free and able to control their private destinies ; the liberties of each based upon the perogatives of ownership ; the volition of each in the quest for happiness and affluence expressed through the powers of property ; with the energies of all fused and channelized as a force for efficiency and progress through market competition ; and with resources allocated and income distributed through the autonomous movements of market price — for market price was seen as the true and beneficent « invisible hand » that equated price to cost, and income to reward, value for value. The state was not to impose its clumsy hands into the operations of such a marvel of natural harmony nor had individuals the right to conspire to constrain its operation. Such, then, was the prevailing image of the way things were and, even more, how they ought to be. Correspondingly, the American state was thus designed to constrain collective action ; it was designed for inaction, designed to stumble over itself no matter what its chosen direction ; and the Supreme Court imposed absolute constitutional barriers against virtually any positive action by the state vis à vis the private economy and the prerogatives of property. So it was up until that virtual collapse of Western Capitalism in the 1930’s that we call the Great Depression.
Lettre de Paris 3 Octobre 1982
Authors: Crozier Michel
Published: January 2022

En Mars, je vous écrivais au retour de Los Angeles. Aujourd’hui c’est de Washington que je reviens pour essayer de comprendre. A Washington. Paris est beaucoup plus proche, pas seulement parce que le subway s’y appelle métro, que les restaurants chics y sont nouvelle cuisine et les boutiques à la mode dans Les Champs, mais parce que l’afflux des personnalités politiques et financières y crée une rumeur internationale dont la France n’est pas aussi absente que sur les autoroutes de Californie.
The First Year of Socialist Government in France
Authors: Balassa Bela
Published: January 2022

With the election of Francois Mitterrand to the Presidency on May 10, 1981. and the subsequent election of an overwhelming socialist majority in the National Assembly, the French electorate not only turned its back on twenty-three years of government by the center-right but it brought to power a party that clearly delineated itself from the old socialist party, the SFIO. which had led several governments during the Fourth Republic. In his speeches and writings between 1977 and 1981, Mitterrand repeatedly expressed the view that the social democracy, represented by the SFIO, “has not gone far enough in the reforms and, in particular, it has not appropriated the means to create a radical break with capitalism, by taking away its most
Le Syndicalisme face au changement
Authors: Landier Hubert
Published: January 2022

L’évolution de la situation économique, le changement de majorité politique et les modifications intervenues dans la législation sociale depuis deux ans représentent, pour le syndicalisme français, une véritable mutation par rapport aux conditions dans lesquelles s’exerçait jusqu’alors son action.
Efficient Fishing Method to Control the Population of Rice Eel, Monopterus albus (Synbranchidae) in Rice Fields in Cagayan Valley, Philippines
Authors: Ame Evelyn , Mayor Aeron
Published: January 2022

Rice eel (Monopterus albus) was introduced in the Philippines in 1905 as an aquaculture species without a thorough evaluation of its possible negative impact on the environment. In Cagayan Valley Region, it is being considered as a pest due to the economic loss it brought to farmers as it bore holes on the dikes, draining the water from the rice field, thus, contributing to the additional expense of the farmers. However, from the economic point of view, the species offered great potential as an export commodity due to its broad export market in East Asian countries. Hence, this study was conducted to determine the most efficient and effective method of controlling the proliferation of rice eel in rice fields in the Cagayan Valley region while preserving its integrity as an export commodity. Twelve (12) municipalities were chosen as the study sites based on validated reports of the high occurrence of rice eel. Three fishing methods, namely, fish trap (FT), hook and line (HL), and electrofishing (EF) gadget, were utilized. These gears were set during the dry and wet seasons. Catch and catch per unit effort (CPUE) were used to determine gear efficiency, while monetary values, net income, and ROI were used to assess the profitability of the gears. Results showed that electrofishing gadgets exhibit greater efficiency among the three fishing gears. The EF gadget also has the highest CPUE (4 individuals) per hour while only around 0–1 per hour for FT and HL. Seasonality does not affect the efficiency of the three fishing gears. Also, there is no significant interaction between seasons and fishing gears (p = 0.525). Computed annual net income and return on investment (ROI) is also greater using EF (PHP 407,630.40/ha/year with 569% ROI) compared to HL and FT (net incomes of PHP 113,244.68/ha/year and PHP 161,618.99/ha/year, and 261% and 309% ROI, respectively). However, the use of EF as a control measure should entail restrictions such that only within rice farm areas and not in open waters and only after harvest or before planting with issued EF licenses and permits from BFAR and local ordinances. Higher penalties should also be imposed for illegal use of EF such as use in open waters. As an alternative to EF, a combination of FT and HL with modifications or more environment-friendly fishing gears can be explored to catch and control the rice eel population.
Population Density, Distribution, and Species Composition of Sea Cucumbers in Pagasinan Tidal Flat, Bongao, Tawi-Tawi, Philippines
Authors: Ajik Jaro , Ajik Mohammad-Norodom , Tahiluddin Albaris
Published: January 2022

This study investigated the population density, distribution, and species composition of sea cucumbers in Pagasinan Tidal Flat, Bongao, Tawi-Tawi, Philippines. Sea cucumbers were collected in the night along the tidal flat and by snorkeling along the reef area. The study recorded seven species belonging to genera Holothuria (five species), Bohadschia (one species), and Stichopus (one species). The population densities ranged from 0.09 ± 0.5 to 3.85 ± 1.67 individuals per 100 m2 each with varying habitat preferences.
Legal Regulation Development of Innovative Entrepreneurship and Innovative Markets
Authors: Isaev M. N.
Published: January 2022

The article considers the directions of development of legal regulation of innovative entrepreneurship and innovative markets in the digital age. World practice shows that there is a distortion of competition in digital markets, prerequisites for some form of monopolization of markets arise. This damages producers, consumers, and the country as a whole. Therefore, as shown in the article, the state can develop antimonopoly regulation in a number of directions, depending on the specifics of the market.
Livedo of the Forearm in the Aftermath of Forearm Erysipelas
Authors: E. Naschitz Jochanan
Published: January 2022

Livedo is an ischemic dermopathy caused by vasculopathies or prothrombotic states, and characterized by the violaceous lace-like mottling of the skin. We report on a patient who developed livedo reticularis – livedo racemosa overlap syndrome as a late sequel of erysipelas, the livedo being restricted to the limb segment affected earlier by erysipelas and devoid of systemic vasculopathy. Though erysipelas and livedo are common disorders, we could not find in the literature reports of an occurrence like that observed in this patient. In this case a favorable prognosis of livedo could be predicted. In a different context, livedo may be the alarming signal of an undiagnosed systemic disease.
The Bacterial Cytoskeleton based on Bacterial Translation Elongation Factor EF-Tu: Novel Insights
Authors: Mayer Frank
Published: January 2022

Bacteria possess an EF-Tu-based cytoskeleton.This article presents a short review. A number of questions which are not discussed in the former publications can be asked, such as: all bacteria possess a ribosomal protein synthesis system and, hence, also EF-Tu. EF-Tu is produced in an amount that is higher than the need for a function as translation elogation factor in ribsomal protein synthesis. This article tries to answer the question regarding the surplus of EF-Tu: formation of a "cell-wide web" by self-assembly as a feafure that stabilizes cell integrity. An additional question can be asked: what is the origin of this bacterial cytoskeleton? This article contains a speculation on this topic. A third question regards the'ntteructjon of ribosomes in the process of protemsynthesis: does the EF-Tu protein move to the ribosome, or does the ribosome move to the EF-Tu intergated in a fibril of the bacterial cytoskeleton? The former publication depicts electron micrographs which show colocalizatton of botth entities. EF-Tu is an example for aprotein with two independent functions: participation in the ribosomal protein synthesis as a kanslation elongation factor, and component of a bacterial cytoskeleton. This situation can open up a discussion ofthe sequence of events and states of early cells during evolution.
STRUCTURE OF EXCRETORY DUCTS OF EXTRAAND INFRAORBITAL GLAND OF LABORATORY RATS
Authors: Katsenko A. L.
Published: January 2022

The aim of the study. To find out and compare the structure of the excretory ducts of the extraand infraorbital lacrimal gland of the laboratory rat. Object and methods. Five male laboratory rats were examined by dissecting the lacrimal glands, from which a series of thin paraffin sections were obtained for histological examination. Micropreparations were stained with hematoxylin and eosin and examined under a light microscope. Results. It was found that the tubular-alveolar epithelial components of the extraorbital gland of rats inside the lobe are even denser than in the infraorbital gland, as evidenced by very narrow interstitial fissures. The lacrimal glands of laboratory rats have an individual well-defined connective tissue capsule. Inside and between the lobes there are slit-like interpithelial interstitial spaces, in which we do not detect an accumulation of lipocytes, as occurs in the lacrimal glands of man. In the volume of lobes such as the extraorbital and infraorbital glands, the interpithelial interstitial spaces contain vessels of the hemicrocirculatory tract, mainly capillaries, precapillary arterioles and postcapillary venules. Arterioles and venules are usually visualized outside the lobes in more pronounced interstitial spaces. Conclusions. 1. The epithelial tubular structures of the lacrimal gland of the laboratory rat form a complex-branched system of excretory ducts, in which there are no typical intercalated ducts, which would be the connecting component between the terminal section and the excretory duct system. 2. The absence of intercalated ducts leads to a change in the appearance on histological specimens of tubulo-acinar aggregates of the lacrimal glands of rats in favor of tubuloalveolar assemblages. 3. Among the excretory ducts of the lacrimal glands of the laboratory rat, the following can be distinguished: intra-lobular, lobular and common excretory ducts, through which the secret is produced. The common ducts of the extraand infraorbital lacrimal glands, as a rule, combine to form their common duct.
LAPAROLIFTING IN PERFORMING LAPAROSCOPIC CHOLECYSTECTOMY IN PATIENTS WITH COVID-19
Authors: Zaiets S.M. , Dudchenko M.O. , Ivashchenko D.M.
Published: January 2022

Starting in March 2020, when doctors faced the onset of the coronavirus disease (SARS-CoV-2) pandemic, the surgical service faced new challenges: the growth in abdominal emergencies and the presence of the COVID-19 as a concomitant disease. Respiratory infection requires finding ways to improve the performance of surgical laparoscopic interventions, since all patients have respiratory disorders. One method that can help is laparolifting or "gasless laparoscopy." The aim of the study was to investigate the efficacy and safety of the gasless laparoscopy (laparolifting) method for endoscopic cholecystectomy in patients with COVID-19 co-infection. We analyzed the clinical data of patients with acute destructive cholecystitis and COVID-19 co-infection who underwent laparoscopic cholecystectomy by applying a laparolifting device and compared them with standard surgery by using carboxy-peritoneum. According to the data obtained, we can suggest that the use of "gasless laparoscopy" method in the presence of respiratory distress syndrome in patients with COVID-19 reduces the need to increase the peak inspiratory pressure during intubation anesthesia, and over the postoperative period this method has a positive effect on the patients’ need in oxygen to achieve the good saturation. Having analyzed laboratory parameters, we can conclude that both methods are comparable and do not cause critical shifts in the body's homeostasis. According to our study, laparolifting is a safe technique that also reduces pain syndrome intensity after surgery and does not seriously restrain the patient's activity. Therefore, we can recommend the use of laparolifting when performing laparoscopic cholecystectomy in patients with COVID-19.
CURRENT ASSESSMENT OF DIAGNOSIS AND INTEGRATED TREATMENT OF LIVER ECHINOCOCCOSIS
Authors: Abbasalieva P.M. , Nasirova M.Y.
Published: January 2022

Purpose: to improve the results of diagnostics and treatment of patients with liver echinococcosis by applying the most appropriate methods and means of integrated therapy. Methods. When analyzing the material of conservative treatment using Immunofan, attention was drawn to the dynamic changes in the laboratory parameters under the study during and after the treatment. On the 1st, 3rd, 5th, 10th days of the postoperative period, we investigated the functional state of the liver in the patients by the level of total protein and its fractions and a blood test for bilirubin content, amylase, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase, gamma-glutamine transferase (GGT). Results. Some biochemical indices and red blood indices revealed that there was an increase in the level of cytolytic enzymes (AsAt, AlAt) under moderate hyperbilirubinemia. The results of the use of the drug Immunofan in the treatment of patients with severe liver echinococcosis demonstrated a significant decrease in cytolysis and cholestasis indicators, as well as an increase in the albumin content over all stages of laboratory studies; moreover, its indicators significantly grew up from 38.5±0.3 g/L to 40, 7±0.2 g/L, respectively, on the 1st and 5th day after the beginning of the course of standard therapy (t=3.2; p <0.001). At the final stage of the research, the protein content increased to 41.9±0.3 g/L, versus 42.6±0.6 g/L, which were reference values for this factor in the control group of healthy individuals (p >0.05). We observed a decrease in cholestasis indices in the patients: cholesterol in the main group significantly lowered from 210.5±1.9 mg/dL to 205.6±0.8 mg/dL, respectively, before the treatment and in 5 days of the therapy (t=4,9; p <0.001), but was still higher compared to the control group at the initial stages of observation, when the dynamics of the decline was significantly slower. There was a significant (t=18.0; p <0.001) increase in C-reactive protein (CRP) values on day 1 of the postoperative rehabilitation period in the main group of patients with liver echinococcus (from 9.5±0.4 mg/L to 12.6±0.5 mg/L, respectively, before treatment and at the indicated time) compared to the control group, where the indicators were 3.6±0.2 mg/L. Conclusions. This study has proven the diagnostic and prognostic significance of the proposed method for the treatment of liver echinococcosis and prevention of its complications. Their efficacy has been supported by the analysis of laboratory data reflecting the capability of the biosynthetic function of the liver.
SURGICAL TREATMENT OF LOCAL PURULENT-SEPTIC COMPLICATIONS OF ACUTE SEVERE PANCREITIS
Authors: Cherkun O.Yu.
Published: January 2022

In the past decades, mortality in acute pancreatitis ranges from 3 to 15 % and depends mainly on the specific weight of severe forms of morbidity, which is characterized by the development of necrotic processes in the pancreas and systemic complications. Despite the large number of studies on severe forms of acute pancreatitis, a significant improvement of results of treatment of this category of patients is not observed. The integrated diagnosis and treatment of this pathology, prognosis and prevention of purulentseptic complications are relevant today. The aim of the study was to evaluate the effectiveness of surgical tactics depending on the nature and prevalence of local purulent-septic complications of acute pancreatitis. To solve this problem, the results of treatment were analyzed the results of treatment of 422 patients with acute pancreatitis who were treated in the surgical Department of the Poltava regional clinical hospital in the period from 2010 to 2015. All patients were admitted to hospital for 1-7 days after infection. 315 (74.6 %) of them are diagnosed as having acute pancreatitis easy, patients received conservative therapy and 7-10 days was discharged from the hospital. Moderate and severe pancreatitis with the development of local parapancreatic complications were diagnosed in 107 patients (25, 4%), 67 (62.6%) men and 40 (37, 4%) women. Their age ranged from 22 to 81 years (47, 9±1.5 years). The severity of the patients was determined by the BISAP scale, the presence of organ failure was diagnosed by applying the Marshal scale (modification 2012) [5]. The patients were examined according to the order Ministry of Healthcare of Ukraine № 297 dated 2 April 2010. Moderate acute pancreatitis is characterized by localization of purulent-septic complications in 12 anatomical areas with a predominantly liquid component. Severe acute pancreatitis is characterized by the localization of purulent-septic complications in more than 2 anatomical sites with primarily tissular component. Efficacy of simple drainage procedures depended on the incidence of fluid accumulations in the 1-2 anatomical region and presence of a predominantly liquid component. Among the patients with predominant tissue component in the liquid accumulation and the prevalence of local parapancreatic complications in more than two anatomic sites, the performance of open necrosectomy seems to be the most appropriate.
Recidiva paraesofágica de hernia hiatal. Diagnóstico radiológico y resolución quirúrgica laparoscópica
Authors: Varela Martín , Muniz Nicolás , Pouy Andrés , Haro Camila , Mansilla Sofía
Published: January 2022

La tasa de recidiva radiológica luego de la cirugía de las hernias hiatales grandes tipo IV es cercana al 50%. La mayoría de las veces la recidiva supone un ascenso parcial de la funduplicatura al tórax (telescopaje), y si no tiene expresión clínica puede optarse por un manejo conservador (solo 3-6% requieren cirugía de revisión). Sin embargo, en ocasiones hay otro tipo de recidivas (paraesofágicas) que deben valorarse mediante estudios funcionales, endoscópicos y radiológicos, que dan disfagia con mayor frecuencia.

Un tránsito contrastado digestivo superior permite en este caso identificar el tipo de recidiva herniaria, con migración parcial del fundus gástrico hacia el tórax paraesofágico izquierdo, y una funduplicatura continente pero realizada técnicamente en por debajo de lo deseable (cuerpo alto) (figura).

La resolución del cuadro implica la reducción de la hernia a la cavidad abdominal, con cierre del defecto diafragmático, desmontar la funduplicatura anterior anatomizando la zona y la reconfección de una nueva funduplicatura.
ESTIMATION OF HYPERTENSION RISK FROM LIFESTYLE FACTORS IN COASTAL POPULATIONS
Authors: Ismah Zata , Purnama Tri Bayu , Falefi Reinpal , Mawar Luthfiah , Lestari Cindy , Nst Citra Cahyati
Published: January 2022

The prevalence of hypertension in coastal areas was still high between 2007 and 2018 with the highest prevalence in 2007 at 53.3%. The purpose of this research was to analyze the prediction of hypertension based on the determinants of the lifestyle of the coastal population. The type of this research is using cross-sectional research design, with a total sample of 210 people in the coastal area of Medan Belawan. The data were collected using an instrument in the form of a questionnaire, body mass index measurement using a manual weight balance and a stature meter and blood pressure using an sphygmomanometer aneroid. The selection of candidates as predictive variables is carried out by chi-square test analysis, followed by multivariate analysis using binary logistic regression test and the formulation model to find predictions hypertension, namely age â‰¥ 45 years has a 3.040 times greater risk of suffering from hypertension than age < 45 years (p = 0.001; 95% CI = 1.549-5.966) and obesity nutritional status has a large 2.284 times greater risk of suffering from hypertension than nutritional status was not obese (p = 0.028; 95% CI = 1.091-4.780). The results of the calculation of the probability from the modeling, it is found that if a person is â‰¥ 45 years old and has a nutritional status of obesity, the probability of suffering hypertension is 99.99%.
Niveles de actividad física y uso del smartphone en estudiantes de pedagogía en educación física: estudio comparativo en dos momentos de la pandemia
Authors: Etchevers-Rivas Valentina , Navarrete Oviedo Michael , Valdés Rojas Gabriel , Merellano Navarro Eugenio
Published: January 2022

La pandemia ha generado que la práctica de actividad física disminuya por las medidas sanitarias y el tiempo de uso de los dispositivos móviles incremente significativamente para diversas funciones. Objetivo: comparar y relacionar los niveles de actividad física y tiempo de uso del smartphone. Método: los instrumentos que se utilizaron para la recolección de datos fueron el cuestionario internacional de actividad física (IPAQ) en su versión corta validada en el contexto chileno y la aplicación “Tiempo en pantalla, restricción y control parental” disponible para usuarios Android y iPhone. La primera muestra estuvo compuesta por 127 estudiantes y la segunda, que se recolectó un mes después, alcanzó un número de 68 estudiantes. Resultados: Los principales hallazgos de este estudio fueron que más del 60% de los estudiantes de Pedagogía en Educación Física que participaron de esta investigación presentan moderados y altos niveles de actividad física durante las dos mediciones. El tiempo promedio diario de uso del smartphone durante las dos mediciones se mantuvo en una media superior a 350 minutos diarios. Para efectos de este estudio no hubo una correlación entre los niveles de actividad física y tiempo de uso del smartphone. Conclusión: Más del 70% de los estudiantes cumplen con las recomendaciones de actividad física de la OMS durante las dos mediciones. El tiempo de uso del smartphone es moderado en las dos mediciones y no influyó en la práctica de actividad física de los estudiantes.
Can fear of failure predict academic procrastination? A study of Indonesian university students
Authors: Karim Nur Fauziah , Minarni  , Alim Syahrul
Published: January 2022

This study aims to determine the ability of fear of failure in predicting academic procrastination in students in Indonesia by involving 428 respondents (male = 52.63%). The instruments used are the academic procrastination scale and the fear of failure scale. Analysis of this research data uses a simple linear regression technique. This study showed that fear of failure affected academic procrastination significantly with a contribution value of 38.6% positive direction, while 61.4% was influenced by other factors not studied. Research confirms that students with high levels of fear of failure tend to have high levels of academic procrastination and vice versa
Synthesis and Biological Evaluation of N-Heterocyclic Substituted Fluoro-Benzothiazole Sulphonamido Analogs as a Potential Therapeutic Agents
Authors: T Sri Ranga. , Chaubey Neelesh
Published: January 2022

The present investigation is aimed to synthesize fluorobenzothiazole comprising sulphonamido pyrazole analogs starting from fluoro-chloroaniline  to get 2-amino-6-fluoro-7-chloro (1,3) benzothiazole (I), this was treated with anilino-s-methyl ethylene cyanoacetamide  in the presence of ethanol to get desired molecules. The synthesized targeted molecules are characterized, docked and screened  for their invitro antidiabetic properties.

Keywords: Fluorobenzothiazole, Docking, antidiabetic
Gestión de proceso en la Universidad Politécnica Estatal del Carchi
Authors: Díaz Cabezas Hernán Rodrigo
Published: January 2022

El presente trabajo de investigación se realizó como finalidad, diseñar una propuesta de mejora para el proceso de evaluación del docente de la Universidad Politécnica Estatal del Carchi (UPEC), que permita integrar las actividades de docencia, investigación y gestión académica. Para lo cual, se recurrió a la aplicación de la metodología QFD. Los principales resultados sugieren que las necesidades (los QUÉ) más relevantes, que los clientes esperan satisfacer del proceso de mejora son docentes más responsables (4,368), docentes más dedicados (4,345) y docentes más actualizados (4,291); después, el análisis de los requerimientos técnicos (los CÓMO) reveló que, para satisfacer las expectativas de los clientes la Comisión General de Evaluación Interna, debe enfocarse en las especificaciones técnicas de la metodología de la CGEI (17,28%), debido a que el 73% de los estudiantes y el 6,56% de los docentes desconocen cómo se valora el desempeño del docente. Con base a los resultados anteriores, en la propuesta de mejora se introdujo la socialización y los fines del proceso de evaluación del docente. Finalmente, si se implementara la propuesta, la UPEC estaría ahorrando anualmente el 23,85% de los costos actuales, es decir, $9.300,00 que puede destinarse para otras actividades que garanticen la calidad de la educación superior.