bluuebunny/crossref_metadata_2025 huggingface dataset:
Makedonya Örme Kültüründe Hayvan Figürlü Çoraplar
Authors: EROĞLU Mehmet Ali , AKPINARLI Feriha
Published: September 2023

Türk sanatının kökenleri Orta Asya Bozkırlarından başlayarak, günümüz Anadolu topraklarına ve Balkanlara kadar uzanmaktadır. Uzun yıllar Osmanlı hakimiyetinde kalan Balkan coğrafyasının bir çok ülkesinde Türk sanatının izlerini görmek mümkündür. Türk sanatının Balkanlarda uzun bir süre görüldüğü ülkelerden birisi de Makedonya’dır. Özellikle Üsküp, Osmanlı Mimari eserlerinin günümüze kadar ulaştığı ve Osmanlı el sanatlarının görüldüğü bir yerleşim yeridir. Osmanlı’nın Balkanları fethi ile birlikte Anadolu’dan Balkanlara kültür-sanat göçü de yaşanmıştır. Bu kültür-sanat göçüyle Kuzey Makedonya’da Osmanlı sanatının izleri görülmüştür. Bu izler günümüzde Kuzey Makedonya’nın önemli simgelerinden biri olan Üsküp Türk Çarşısında günümüze kadar devam etmektedir. Üsküp Türk çarşısında, Türk el sanatlarının izlerinin görüldüğü birçok işyeri bulunmaktadır. Bu iş yerlerinde gerek Türk kültürü gerekse Balkan kültürünün özelliklerini yansıtan ürünlerin teşhir ve satışı yapılmaktadır. Mayıs 2022’de Türk sanatının Balkanlardaki izlerini tespit etmek amacıyla Kuzey Makedonya’da Üsküp ve Kalkandelen, Kosova’da Prizren ve Priştine, Karadağ’da ise Rojea, Akova ve Berane bölgelerinde alan araştırması yapılmıştır. Alan araştırmasının bir bölümünü oluşturan Kuzey Makedonya Üsküp çarşısında Türk kültürü ile benzerlik gösterebilecek örme çoraplar ve el dokumaları ile ilgili araştırmalar yapılmıştır. Alan araştırması esnasında Hamza Murat isimli koleksiyonerin örme çorap arşivi fotoğraflanarak incelenmiştir.

Bu çalışmada Kuzey Makedonya folklorunun bir parçası olan el örmesi hayvan figürlü çoraplar; desen, renk, kompozisyon, hammadde ve teknik özellikleri açısından incelenmiş, literatür bilgileri ile desteklenerek kataloglanmıştır.
Removal of Manganese Ion Using Integral Membrane Incorporated with Rice Husk Ash
Authors: Kassim Shaari Norin Zamiah
Published: September 2023

Wastewater treatment is a method of ensuring that the water supply is clean and free from contaminants. Manganese is a pollutant that needs to be removed from the water as it is harmful and usually triggers concern about water quality and water distribution system issues. Besides the adsorption method, membrane technology is efficient due to its mild and environmentally friendly process. This research focused on the production of integral membranes from a blend of polyvinyl alcohol/chitosan/polysulfone/polyethylene glycol cross-linked with silica extracted from rice husk ash (RHA) by using the phase inversion method. The silica was incorporated into the membrane formulation through a sol-gel reaction. The goal of this research was to determine the potential utilization of silica from RHA in the membrane’s formulation to remove manganese ions from various concentrations of manganese solutions. The loadings of RHA were varied at 2, 3 and 5 % wt./wt. polymer. The formulated membranes were then characterized in terms of thermal stability by Thermogravimetric analysis, functional group by Fourier Transform Infrared Spectroscopy, and surface morphology by Scanning Electron Microscopy. The performances of the membranes were tested through filtration of manganese ions solutions and antifouling analysis. The results showed that all membranes including membranes from the polymer blend were able to remove more than 94 % manganese ions. However, the membrane incorporated with 2 % RHA portrayed the best performance in terms of obtaining the highest flux for both water and manganese as feed solution respectively, which also resulted in the highest relative flux recovery ratio at 62.50 % from the antifouling analysis. These findings have proven the successful incorporation of RHA in the form of silica powder, which shows the potential utilization of RHA in membrane fabrication.
Fabrication and Characterization of Polyurethane/Graphene Composite: Study on Conductivity and Thermal Properties
Authors: Syed Ismail Sharifah Nafisah
Published: September 2023

This study investigated the potential of graphene for improvement of properties of thermoplastic polyurethane (PU) composites in sight of thermal property, electrical conductivity, hardness, gel content and bonding spectra (FTIR). Polyurethane/graphene (PU/G) composites were synthesized by exfoliating graphene with DMF and then blending it with PEG and IPDI via in-situ addition polymerization with varying graphene concentrations (0–0.18 wt %), resulting in uniform dispersion and partial exfoliation of graphene-sheets in PU matrix. The PU/G synthesis was analyzed by IR spectra analysis, which revealed apparent urethane connections and hydrogen bonding. Glass transition temperature (Tg) property of PU exceeded by around 55 % with the addition of graphene, and it improved steadily as graphene concentration increased. 7B pencil hardness replicated the hardness of the PU/G2, indicating an improvement in hardness. The inclusion of graphene had less of an influence on the gel content of PU, with a proof showing that all of the results gel content was between 80 – 90 %. With the addition of 0.088 % graphene to PU, the electric conductivity improved to 76 %. The composite's conductivity was improved due to graphene's capacity to conduct electricity and the covalent link between PU and graphene.
Seleksi Marka SSR untuk Toleransi Terhadap Cekaman Suhu Tinggi pada Populasi F2 Padi
Authors: Manalu Victor Manotar Pademan , Wirnas Desta , Sudarsono Sudarsono
Published: September 2023

Penelitian ini bertujuan untuk memperoleh primer SSR terpaut toleran terhadap suhu tinggi dengan menggunakan bulked segregant analysis (BSA) dan dilanjutkan dengan single marker analysis (SMA). Penelitian dilakukan di Laboratorium Biologi Molekuler Tanaman, Departemen Agronomi dan Hortikultura, Institut Pertanian Bogor (IPB). Bahan genetik yang digunakan DNA tetua IPB 4S, Situ Patenggang, DNA dari genotipe F2, 12 Primer SSR. Hasil penelitian menunjukkan primer SSR RM 337 mengikuti segregasi hukum Mendel, kemudian berdasarkan  single marker analysis dengan menggunakan karakter bobot gabah bernas menunjukkan primer SSR RM 337 terpaut toleran terhadap suhu tinggi dengan nilai peluang yang sangat nyata. Genotipe F2 yang memiliki pola pita DNA seperti Situ Patenggang (Tetua toleran) dan daya hasil tinggi menghasilkan 54 genotipe F2. Diferensial seleksi berdasarkan genotyping dengan menggunakan primer RM 337 menghasilkan kenaikan bobot gabah bernas sebesar 37.96%.
On the Formalization of Gram-Schmidt Process for Orthonormalizing a Set of Vectors
Authors: Okazaki Hiroyuki
Published: September 2023

In this article, we formalize the Gram-Schmidt process in the Mizar system [2], [3] (compare another formalization using Isabelle/HOL proof assistant [1]). This process is one of the most famous methods for orthonormalizing a set of vectors. The method is named after Jørgen Pedersen Gram and Erhard Schmidt [4]. There are many applications of the Gram-Schmidt process in the field of computer science, e.g., error correcting codes or cryptology [8]. First, we prove some preliminary theorems about real unitary space. Next, we formalize the definition of the Gram-Schmidt process that finds orthonormal basis. We followed [5] in the formalization, continuing work developed in [7], [6].
Denture Base Polymer Biodegradation: In Vitro Study
Authors: Cerghedi Alessandra-Aniela , Fazakas Zita , Székely Melinda , Biriș Carmen , Molnar-Varlam Cristina
Published: September 2023

Introduction

Acrylic resins are the most frequently used materials for the bases of prostheses, and are also used in the re-optimization and the repair of prostheses.

The aim

of our study was to investigate whether direct contact with the resin causes decomposition of methyl methacrylate and formation of ketone bodies in the oral cavity.

Material and methods

The in vitro study included 12 samples of autopolymerized polymethyl methacrylate and 8 samples of thermopolymerized polymethyl methacrylate. Some of the resin samples were intentionally prepared incorrectly, with modified powder to liquid ratios or thermal regime, to be able to compare them with samples prepared according to the manufacturer’s instructions. Some of the samples were immersed in gastric juice or alcohol for 48 h at 37 °C in a thermostatic bath to simulate the environment and temperature of the oral cavity, while others were kept at room temperature. The Legal reaction was used to identify the presence of ketone bodies in the solutions.

Results

The samples that were prepared incorrectly and were kept at 37 °C were the most affected. The presence of ketone bodies was demonstrated by the formation of a precipitate on the bottom of the test tube and the color change of the solution. Samples that were kept at room temperature were less affected, both from a spectrophotometric and biochemical point of view.

Conclusion

The quality of polymethyl methacrylate can be improved by respecting the manufacturer’s instructions and work protocols, and by avoiding substances that are considered aggressive, such as gastric juice, alcohol, and local factors in the oral cavity.
ТЕХНОЛОГИЯ СОЗДАНИЯ ПРОСТРАНСТВЕННЫХ ДАННЫХ В РЕГИОНАЛЬНЫХ ИНФОРМАЦИОННЫХ СИСТЕМАХ В ЦЕЛЯХ УСТОЙЧИВОГО РАЗВИТИЯ КОРЕННЫХ МАЛОЧИСЛЕННЫХ НАРОДОВ СЕВЕРА
Authors: Павлова Мария Борисовна
Published: September 2023

В последнее время резко возрос интерес к освоению природных ресурсов севере-восточной части России. Рост деятельности горнодобывающей отрасли в этом направлении обусловлен увеличением потребности в промышленном производстве в мире. Добывающие компании ежегодно вовлекают в свою деятельность все больше территорий исконных угодий коренных малочисленных народов, в результате происходит нарушение среды обитания биологических ресурсов, обеспечивающих развитие их традиционной хозяйственной деятельности.
Исследование направлено на изучение современного состояния объектов традиционного природопользования объединений коренных малочисленных народов в Республике Саха (Якутия) и их формализацию в виде пространственных данных.
В статье показан порядок организации исследований по составлению пространственных данных традиционного природопользования коренных народов Анабарского и Оленекского районов республики. Представлен обзор видов традиционной хозяйственной деятельности коренных малочисленных народов, проживающих на обследуемых территориях. Рассмотрены проблемы, с которыми столкнулись при сборе информации у родовых общин. Составлены пространственные данные по результатам обследования родовых общин коренных малочисленных народов по районам исследования. Научная новизна исследования в том, что впервые проведена работа по систематизации объектов традиционной хозяйственной деятельности коренных малочисленных народов на региональном уровне и уточнены факторы, влияющие на наполняемость тематической базы пространственных данных.
Erkek askeri personelin human papilloma virüsü tarama testi ve aşısına ilişkin bilgi düzeyleri
Authors: Okan Fatih , Kavici Sümeyye , Dincel Işıl Miray , Topcu Kübra , Üstün Sümeyya , Akkoç Merve
Published: September 2023

OBJECTIVES: The aim of the study was to determine the level of knowledge of male military personnel about Human Papillomavirus, screening tests, and vaccination. MATERIALS and METHODS: The descriptive cross-sectional study was conducted with 390 male military personnel working in Provincial Gendarmerie Command between December 2022 and January 2023. Data were obtained using the descriptive information form and the human papillomavirus knowledge scale. Mann-Whitney U test and Kruskall-Wallis test were used to evaluate the data. RESULTS: The mean the human papillomavirus knowledge scale total score of the male military personnel included in the study was 4.89±6.43. In the study, it was found that the total score of the human papilloma virus knowledge scale varied significantly according to marital status, educational status, place of residence, presence of reproductive organ cancer in first-degree relatives or themselves, having received previous education about sexually transmitted diseases and having information about human papillomavirus and sexually transmitted diseases. CONCLUSION: It was found that the total score of the human papillomavirus knowledge scale of male military personnel was quite low. Health professionals who play an important role in protecting and promoting health should plan awareness trainings on human papillomavirus infection and vaccine for military personnel who are among the risky groups and lead the establishment of human papillomavirus vaccination programs for the male population. Keywords: knowledge, military personnel, human papillomavirus, vaccine
Peyronie hastalığı: Cerrahi dışı tedavi yaklaşımları
Authors: Kol Arif , Ateş Erhan
Published: September 2023

Peyronie’s disease is a condition characterized by progressive fibrosis in the tunica albuginea, resulting in deformities such as penile shortening and curvature. This situation not only causes sexual problems, but also can cause an increase in sexual performance anxiety, difficulty in relationship and depression. The course of the disease consists of two periods, acute and chronic. In the acute phase and in the stable disease period, while non-surgical treatments are used to relieve symptoms and regress fibrosis, surgical treatments are on the agenda, especially after serious deformities develop. Non-surgical treatment methods are oral treatments, intralesional injection treatments, topical treatments, vacuum and traction devices and shock wave treatments. Intralesional clostridium histolyticum collagenase treatment has been approved by the US-FDA and it’s indicated in patients with noncalcified plaques. For multimodal treatments, there is no clear consensus yet. Keywords: Peyronie’s disease, penil curvature, medical therapy, vacuum device
The impact of social assistance on households’ transfer behavior: A micro data analysis
Authors: Kristina Anita , Rasyid Mohtar , Purwanti Putu Ayu Pramitha
Published: September 2023

This paper investigates whether public transfers crowd-out inter-household transfers in Indonesia. Using household data from Indonesia Family Life Survey (IFLS-3 & IFLS-4), this study evaluates the impact of direct cash transfer programs (Bantuan Langsung Tunai, BLT) on inter-family transfer (i.e., monetary transfer from parents, siblings, child, and other family members who do not live co-residently). The results indicate that, in general, the crowding-out effect is relatively small. This effect is statistically significant only in urban households but not rural ones. This finding suggests that expanding public transfer under formal social security programs to cover poor households does not significantly reduce the existence of informal transfers. Further, public transfers potentially improve the distribution of household income.
Corporate tax planning, the use of SPV, board independence, and firm value
Authors: Suriawinata Iman Sofian , Almurni Siti
Published: September 2023

Although many studies discuss the significant role of special purpose vehicles (SPVs) in the corporate tax planning context, no prior empirical research exists on the value relevance of such use. Our study fills the gap by investigating the impact of the use of SPVs in corporate tax planning on firm value. Since tax planning is a risky endeavor, of particular interest is the role of corporate governance mechanisms in ensuring that firms select optimal levels of corporate tax planning activities and preventing managerial diversion of tax-saving related cash flows. Using moderated regression analysis on a sample of 119 listed non-financial firms from 2013 to 2017, we find that the use of SPVs in corporate tax planning enhances firm value and that corporate tax planning moderated by board independence also increases firm value.
POLITIK HUKUM HAK PENGELOLAAN ATAS TANAH SESUDAH BERLAKUNYA UU NO 11 TAHUN 2020 TENTANG CIPTA KERJA
Authors: Pradipa Ignatius
Published: September 2023

Hak Pengelolaan merupakan bagian dari hak menguasai dari negara. Isi dari hak pengelolaan mengalami perkembangan sebagaimana tertera dalam regulasi mengenai hak pengelolaan sebelum berlakunya Undang Undang Nomor 11 Tahun 2020 tentang Cipta Kerja dan sesudah berlakunya Undang Undang Nomor 11 Tahun 2020 tentang Cipta Kerja. Seiring dengan politik hukum lahirnya Undang Undang Nomor 11 Tahun 2020 untuk menciptakan lapangan kerja dan investasi, maka khusus pertanahan diaturlah penguatan hak pengelolaan. Diketahui bahwa terdapat perbedaan ketentuan mengenai hak pengelolaan sebelum dan sesudah berlakunya Undang Undang Cipta Kerja mengenai definisi, obyek, subyek, kewenangan, hak atas tanah dan jangka waktu hak atas tanah di atas hak pengelolaan
PELUANG DAN TANTANGAN PELAKSANAAN PATEN ESENSIAL STANDARD (STANDARD ESSENTIAL PATENT/SEP) DI INDONESIA
Authors: Nuradi Rani
Published: September 2023

Standards are technical requirements or something that is standardized, including procedures and methods that are formulated based on the consensus of all parties, the government, and international decisions related to safety, security, health, environmental conditions, advancements in science and technology, experience, as well as current and future developments to achieve maximum benefits. In the current development of technology and global economic competition, patented technologies often serve as standards (Standard Essential Patent, or SEP). The implementation of SEP itself is possible as long as the patent holder agrees and adheres to the principles of fair, reasonable, and non-discriminatory terms, also known as FRAND (Fair, Reasonable, and Non-Discriminatory) principles. When the FRAND principles are not followed, for example, when the patent holder is unwilling to provide a license or sets the licensing fee too high, issues may arise. This paper discusses examples of SEP implementation in Indonesia through two case studies, aiming to provide insights for policymakers, particularly the Directorate General of Intellectual Property and the National Standardization Agency, to take appropriate steps in maintaining a balance between the rights and obligations of patent holders and the public
REKONSTRUKSI KEBIJAKAN TERHADAP PENETAPAN SAKSI PELAKU YANG BEKERJASAMA PADA PERKARA TINDAK PIDANA KORUPSI DITINJAU DARI ASPEK KEPASTIAN HUKUM DAN ASPEK KEMANFAATAN DALAM SISTEM PERADILAN PIDANA TERPADU
Authors: Setiyono Setiyono , Supartono Sugeng , Keumala Dinda , Bakri Khairani
Published: September 2023

Salah satu dari permasalahan yang muncul dalam proses penegakan hukum di bidang pemberantasan tindak pidana korupsi adalah permasalahan yang terkait dengan penetapan status tersangka atau terdakwa sebagai saksi pelaku yang bekerjasama atau justice collaborator. Adanya beberapa permasalahan yang bersumber dari adanya ketidaksamaan pemahaman atau tidak adaya unifikasi kebijakan dalam menetapkan status pelaku sebagai saksi pelaku yang bekerjasama atau justice collaborator oleh para penegak hukum. Selain itu, adanya permasalahan mengenai ketiadaan manfaat yang dialami oleh tersangka atau terdakwa dari penetapan saksi pelaku yang bekerja sama atau justice collaborator tersebut tentunya menimbulkan adanya ketidakpastian hukum dan juga tidak memberikan kemanfaatan atau utilitas bagi pihak yang ditetapkan sebagai saksi pelaku yang bekerja sama atau justice collaborator. Rumusan permasalahan dalam tulisan ini adalah bagaimana pengaturan tentang kebijakan penetapan saksi pelaku yang bekerjasama atau justice collaborator dalam perkara tindak pidana korupsi dan bagaimana rekonstruksi kebijakan penetapan Saksi Pelaku Yang Bekerjasama (Justice Collaborator) dalam perkara tindak pidana korupsi yang memberikan aspek kepastian hukum dan aspek kemanfaatan dalam sebuah sistem peradilan pidana terpadu. Tipe penelitian yang digunakan adalah normatif, dengan menggunakan pendekatan Undang-Undang dan regulasi lainnya. Sifat penelitian deskriptif, dengan menggunakan data sekunder. Analisis penelitian dilakukan dengan cara kualitatif dan metode penarikan kesimpulan secara deduktif. Pada prakteknya terdapat berbagai maca regulasi yang mengatur tentang tentang kebijakan penetapan saksi pelaku yang bekerjasama atau justice collaborator dalam perkara tindak pidana korupsi. Pengaturan tersebut mulai dalam bentuk Undang-Undang sampai dengan bentuk Peraturan Bersama dari lembaga penegak hukum dan Surat Edaran. Berpedoman dari adanya keanekaragaman pengaturan maka diperlukan rekonstruksi kebijakan pembentukan norma hukum baru dalam bentuk Undang-Undang yang menjadi pedoman mengikat terhadap pengakuan atau rekognisi dan pemahaman atau persepsi yang sama secara hukum mengenai penetapan status saksi pelaku yang bekerjasama atau justice collaborator yang berlaku sejak mulai tahapan pemeriksaan di tingkat penyidikan sampai dengan tahapan pemeriksaan di tingkat pengadilan bahkan sampai dengan pelaksanaan eksekusinya demi terciptanya asas kepastian hukum dan memberikan kemanfaatan atau utilitas bagi tersangka atau terdakwa yang ditetapkan sebagai saksi pelaku yang bekerjasama atau justice collaborator
O PROCESSO DE ADEQUAÇÃO À LEI GERAL DE PROTEÇÃO DE DADOS: UM ESTUDO DE CASO EM UMA EMPRESA DO SEGMENTO DA SAÚDE
Authors: Quintanilha Fabiano Santos , Da Silva Vinicius Barcelos
Published: September 2023

Após a criação em 2018 da Lei Geral de Proteção de Dados (LGPD), as organizações brasileiras iniciaram projetos de adequação à LGPD, visando melhorar a segurança da informação, evitando incidentes que possam comprometer a continuidade do negócio e gerar penalidades conforme a lei. O objetivo deste artigo é mostra na íntegra o processo de adequação à LGPD de uma empresa no seguimento da saúde localizada no estado do Rio de Janeiro, com levantamento dos problemas existentes e aplicação das melhores práticas de segurança da informação. Esta adequação ocorreu em um período conturbado de pandemia, onde os custos operacionais no seguimento da saúde foram elevados, o que tornou este trabalho ainda mais difícil. O estudo de caso foi a metodologia empregada neste trabalho, que permitiu uma investigação aprofundada das medidas adotadas pela empresa em seu processo de adequação a nova lei.  Após diversas ações/mudanças organizacionais, culturais e tecnológicas, a empresa conseguiu alcançar o mínimo de adequação às boas práticas de segurança da informação. Como resultado, após o trabalho realizado, não foi identificado nenhum incidente grave relacionado à segurança dos dados na empresa em questão.
Manejo clínico para o transtorno de personalidade borderline
Authors: Martinho Junior Eduardo , Brañas Marcelo José Abduch Adas , Croci Marcos Signoretti
Published: September 2023

O borderline é um tipo de transtorno de personalidade, caracterizado por um padrão generalizado de instabilidade e hipersensibilidade nos relacionamentos interpessoais, instabilidade na autoimagem, flutuações extremas de humor e impulsividade. Por muito tempo, este transtorno foi considerado intratável, mas hoje sabemos que existem métodos eficazes para fornecer melhores condições de vida ao paciente. No ABP TV de hoje, vamos debater o tema "manejo clínico para o transtorno de personalidade borderline". O programa será baseado no artigo Manejo clínico geral para o transtorno de personalidade borderline: um modelo generalista para a América Latina, publicado na revista Debates em Psiquiatria.
Artificial Intelligence vs Human in Advertisement Text Writing
Authors: YILMAZ Aykut
Published: September 2023

This research was conducted to compare the effectiveness of human-generated advertisement text and artificial intelligence (AI)-generated advertisement texts. In this context, data were collected by applying a questionnaire to 208 university students using convenience sampling method. In the questionnaire form, consumer involvement and purchase intention scales were included. Two advertising texts produced by AI and the text used in the original advertisement of the company were presented to the participants. They were asked to answer the scale statements for each ad text. Regression analysis was applied on the collected data. According to the results of the analysis, the most effective ad text on the participants is the ad text printed on ChatGPT, even if with a small difference. As a result, AIs have shown close to human-like success in ad text writing despite using limited data. It is thought that the use of AI in ad text writing will bring efficiency and productivity to the sector.
Computational Characterization of the Reactivity of Compound I in Unspecific Peroxygenases
Authors: Costa Gustavo , Egbemhenghe Abel , Liang Ruibin
Published: September 2023

Unspecific peroxygenases (UPOs) are emerging as promising biocatalysts for selective oxyfunctionalisation of unactivated C-H bonds. However, their potential in large-scale synthesis is currently constrained by their suboptimal chemical selectivity. Improving the selectivity of UPOs requires a deep understanding of the molecular basis of their catalysis. Recent molecular simulations have sought to unravel UPO’s selectivity and inform their design principles. However, most of these studies focused on the substrate binding poses. Few have investigated how the reactivity of CpdI, the principal oxidizing intermediate in the catalytic cycle, influences selectivity in a realistic protein environment. Moreover, the influence of protein electrostatics on the reaction kinetics of CpdI has also been largely overlooked. To bridge this gap, we used multiscale simulations to interpret the regio- and enantioselective hydroxylation of the n-heptane substrate catalyzed by Agrocybe aegerita UPO (AaeUPO). We comprehensively characterized the energetics and kinetics of the hydrogen atom transfer (HAT) step, initiated by the CpdI, and the subsequent oxygen rebound step forming the product. Notably, our approach involved both free energy and potential energy evaluations in a quantum mechanics/molecular mechanics (QM/MM) setting, mitigating the dependence of results on the choice of initial conditions. These calculations illuminate the thermodynamics and kinetics of the HAT and oxygen rebound steps. Our findings highlight that both the conformational selection and the distinct chemical reactivity of different substrate hydrogen atoms together dictate the regio- and enantioselectivity. Building on our previous study on CpdI’s formation in AaeUPO, our results indicate that the HAT step is the rate-limiting step in the overall catalytic cycle. The subsequent oxygen rebound step is swift and retains the selectivity determined by the HAT step. We also pinpointed several polar and charged amino acid residues whose electrostatic potentials considerably influence the reaction barrier of the HAT step. Notably, the Glu196 residue is pivotal for both the CpdI’s formation and participation in the HAT step. Our research offers in-depth insights into the catalytic cycle of AaeUPO, which will be instrumental in rationally designing UPOs with enhanced properties.
Ultrafast 3MLCT quenching and vibrational coherence: excited-state dynamics of the first-discovered Fe(II)-carbene sensitiser resolved
Authors: Pápai Mátyás , Rozgonyi Tamás , Vankó György
Published: September 2023

The application of N-heterocyclic carbene (NHC) ligands represents a groundbreaking advance towards environment-friendly light-harvesting complexes, yet, even the excited-state dynamics of the first-discovered Fe-NHC photosensitiser [Fe(bmip)2]2+ (bmip = 2,6-bis(3-methyl-imidazole-1-ylidine)-pyridine) remain controversial. Using full-dimensional trajectory surface hopping (TSH) spin-vibronic dynamics simulations, we fully resolve and clarify the deactivation mechanism of [Fe(bmip)2]2+. In agreement with the most recent fs-resolved X-ray experiments, we find the excited-state population branches into triplet metal-to-ligand charge transfer (3MLCT) and metal-centered states (3MC) on early sub-ps timescales ~200 fs. The ultrafast 3MLCT quenching by 3MC is driven by multidimensional excited-state ligand motion; it is this deactivation process that ultimately weakens the photosensing efficiency of [Fe(bmip)2]2+. Crucially, the preservation of vibrational coherence along the covalent Fe-C bonds (~300 fs vibrational period) and the appearance of resulting coherent oscillations in various time-resolved experimental data unambiguously evidences the presence of the early sub-ps 3MC component.
Improving Wastewater-Based Epidemiology for New Psychoactive Substance Surveillance by Combining a High-Throughput In Vitro Metabolism Assay and LC−HRMS Metabolite Identification
Authors: Bade Richard , Huchthausen Julia , Huber Carolin , Dewapriya Pradeep , Tscharke Benjamin , Verhagen Rory , Puljevic Cheneal , Escher Beate , O'Brien Jake
Published: September 2023

One of the primary criteria for a suitable drug biomarker for wastewater-based epidemiology (WBE) is having a unique source representing human metabolism. For WBE studies, this means it is important to identify and monitor metabolites rather than parent drugs, to capture consumption of drugs and not fractions that could be directly disposed. In this study, a high-throughput workflow based on a human liver S9 fraction in vitro metabolism assay was developed to identify human transformation products of new chemicals, using α-pyrrolidino-2-phenylacetophenone (α-D2PV) as a case study. Analysis by liquid chromatography coupled to high resolution mass spectrometry identified four metabolites. Subsequently, a targeted liquid chromatography – tandem mass spectrometry method was developed for their analysis in wastewater samples collected from a music festival in Australia. The successful application of this workflow opens the door for future work to better understand the metabolism of chemicals and their detection and application for wastewater-based epidemiology.
Regulating Access to Active Sites via Hydrogen Bonding and Cation-Dipole Interactions: A Dual Cofactor Approach to Switchable Catalysis
Authors: Acosta-Calle Sebastian , Huebsch Elsa , Kolmar Scott , Whited Matthew , Chen Chun-Hsing , Miller Alexander
Published: September 2023

Hydrogen bonding networks are ubiquitous in biological systems and play a key role in controlling the conformational dynamics and allosteric interactions of enzymes. Yet in small organometallic catalysts, hydrogen bonding rarely controls ligand binding to the metal center. In this work, a hydrogen bonding network within a well-defined organometallic catalyst works in concert with cation-dipole interactions to gate substrate access to the active site. An ammine ligand acts as one cofactor, templating a hydrogen bonding network within a pendent crown ether in the secondary coordination sphere, an interaction which prevents the binding of nitriles to the nickel center. Sodium ions are a second cofactor, disrupting hydrogen bonding to enable ligand substitution reactions and substrate binding. Thermodynamic analyses provide insight into the energetic requirements of the different supramolecular interactions enabling substrate gating. Switchable ligand substitution and switchable hydroamination catalysis illustrate the dual cofactor approach.
Power quality improvement in power electronics systems using machine learning
Authors: Jyotsana Kaiwart , Anupama Huddar
Published: September 2023

This study focuses on improving power electronic components and devices, which have gained popularity due to their compact size and precise control over the output voltage and current. They are widely used in renewable energy systems, such as converters and inverters, and in industrial drives as control devices. However, the switching process in power electronic components introduces nonlinear behavior, leading to the generation of harmonics and power quality problems. To address these issues, various methods and techniques recommended by industry standards have been proposed to mitigate or eliminate harmonics and ensure the power quality. These standards provide limits and guidelines for assisting customers and manufacturers in maintaining acceptable power quality levels. Machine-learning algorithms offer a promising approach for improving power quality by leveraging data from a system to make predictions or classifications. In the context of power electronics, machine-learning algorithms can be trained to classify fault types, identify the exact location of faults, predict the remaining life of power electronic components, and detect voltage disturbances. Different machine learning techniques can be employed, depending on the specific application. For example, fault classification and fault location identification can be achieved through supervised learning algorithms, whereas predicting component life and detecting voltage disturbances can utilize techniques such as regression or anomaly detection. By leveraging the power of machine learning, enhanced reliability, performance, and efficiency can be achieved in various applications, thereby contributing to the overall advancement of power electronics technology.
A comparative analysis of different current mirror techniques in 65nm technology
Authors: A. Ashok Kumar , Balaji Narayanam
Published: September 2023

The Current Mirror (CM) technique is widely used in mixed-mode and analog integrated circuits for tasks such as current amplification, biasing, and active loading. The overall effectiveness of these circuits relies heavily on their efficient designs. Current mirrors are primarily employed to accurately replicate currents in a circuit, offering high stability, simplicity, and scalability. They have become indispensable building blocks in analog and mixed-signal circuits, with their significance growing along with the demand for high-performance and low-power designs. Numerous techniques have been proposed to improve the performance metrics of current mirrors, including accuracy, input resistance, output resistance, and bandwidth. This study compares the advantages and disadvantages of these different current mirror techniques on a unified platform. It includes a comprehensive analysis of various contemporary mirror topologies, and classifies them based on their distinct characteristics. The performances of different current mirrors, including the basic CM, Wilson CM, cascode CM, and folded cascode CM circuits, were thoroughly examined in this analysis. The objective of this study is to select an appropriate current mirror for specific applications. The circuits considered in this study accurately mirror a current of 100 µA with a ±2% error using the Cadence Virtuoso software and UMC 65 nm technology. Process, Voltage, and Temperature (PVT) analysis, along with Monte Carlo simulations, were conducted under similar conditions using a supply voltage of 1.2V to ensure a fair comparison across the various current mirror approaches.
SOCIEDADE LIMITADA UNIPESSOAL: DA LIMITAÇÃO DE RESPONSABILIDADE DO EMPRESÁRIO INDIVIDUAL ÀS PERSPECTIVAS DE DESENVOLVIMENTO SOCIAL E ECONÔMICO NO ESTADO DO PARÁ
Authors: Gluck Luciana Neves , Américo Gladson Pereira
Published: September 2023

RESUMO: O presente artigo se propõe a analisar de que maneira de que maneira a Sociedade Limitada Unipessoal pode contribuir para o desenvolvimento social e econômico no Estado do Pará. Para alcançar esse objetivo, contempla, na primeira seção, contextualização da discussão jurídico/doutrinária da limitação de responsabilidade da figura empresarial concretizada sem multiplicidade de sócios. Em um segundo momento, investiga-se a forma de aplicação dessa discussão no Ordenamento Jurídico Brasileiro, em especial com a Lei nº 12.441/2011, que instituiu a EIRELI e a Lei nº 13.874/2019, que viabilizou o surgimento das Sociedades Limitadas Unipessoais. Em seguida será apresentado o diálogo entre o debate estritamente jurídico e as razões que conduziram à sua aceitação, para, por fim, indicar a relevância do recente permissivo legal para o estado do Pará, representativo dentro da realidade amazônica, com potencial repercussão na estruturação de negócios e produtividade no setor privado local, a ser apurado nos próximos anos, também enquanto fomento da Responsabilidade Social Empresarial e dos fatores Ambientais, Sociais e de Governança.
Designing a social exercise app to combat the negative effects of social media on body image amongst young Chinese woman
Authors:   , Yu Yi
Published: September 2023

This study aims to design an app to alleviate the negative impact of social media on young Chinese women's body image, and instead, strengthen their connection to others through a digital design that matches individuals with a workout partner and promotes their physical activity. Human-centered design methodology and methods such as literature review, interviews, rapid prototyping and user testing helped to gain understanding of young Chinese women and develop guidelines and a prototype that matches those. The prototype iterations were designed based on knowledge from the literature and then refined through interviews and user testing. Self-Determination Theory, alongside research on social media, social comparison and social support guided the design. Furthermore, interviews and user testing with participants highlighted important aspects for the design. This study offers a possible way to mitigate the negative impact of social media on body image amongst young Chinese women. The final prototypes alongside the design guidelines can help designers gain understanding of the negative influences of social media and mitigate those through design. Future research could explore further the long-term impact of the design and the social comparison and social support influences on one’s well being and body image.
Application of Unilateral Double-Channel Endoscopic Lamina Fenestration Decompression in Lumbar Spinal Stenosis
Authors: Wei Bo
Published: September 2023

Objective: This paper aims to observe and explore the application effect of unilateral double-channel endoscopic lamina fenestration decompression in the clinical treatment of patients with lumbar spinal stenosis. Methods: The study period is from January 2020 to December 2022, 60 patients with lumbar spinal stenosis were recruited and divided into the control group (traditional interlaminar fenestration) and the study group (unilateral double-channel endoscopic lamina fenestration decompression) according to the method of coin tossing, with 30 cases in each group. The operation time, perioperative blood loss, incision diameter, total hospitalization time, postoperative complications, Japanese Orthopedic Association (JOA), Numerical Rating Scale (NRS) pain score, and excellent rate of lumbar recovery were compared. Results: The operation time of the study group was longer than that of the control group, the amount of perioperative blood loss was lower than that of the control group, the incision diameter was smaller than that of the control group, and the total hospitalization time was shorter than that of the control group (P < 0.05). Postoperative complications such as dural tear, cerebrospinal fluid leakage, infection, and paravertebral muscle injury in the study group were less than those in the control group (P < 0.05). The JOA score of the study group was higher than that of the control group, and the NRS score was lower than that of the control group 6 months after operation (P < 0.05). The operation effect was evaluated according to the modified MacNab standard 6 months after operation, and the excellent rate of lumbar spine recovery in the study group was higher than that in the control group (P < 0.05). Conclusion: Unilateral double-channel endoscopic fenestration decompression of the lamina has a definite application effect, it can significantly reduce postoperative complications of lumbar spinal stenosis, and promote the recovery of lumbar spine function. It has the advantages of mild pain, high safety, less bleeding, small incision, and other advantages, which can be recommended in the treatment of lumbar spinal stenosis.
IDENTIFYING FRAUD IN ONLINE TRANSACTIONS
Authors: Sen Sneha
Published: September 2023

Fraudulent credit card transactions must be when customers are charged for items that they did not purchase. Such problems can be tackled with Data Science and its importance, along with Machine Learning, cannot be overstated. This project intends to illustrate the modelling of a data set using machine learning with Identifying Fraud in Online Transactions. The Identifying Fraud in Online Transactions problem includes modelling past credit card transactions with the data of the ones that turned out to be a fraud. This model is then used to recognize whether a new transaction is fraudulent or not. Our objective here is to detect 99.99% of the fraudulent transactions while minimizing the incorrect fraud classifications. Identifying Fraud in Online Transactions is a typical sample of classification. In this process, we have focused on analyzing and pre-processing data sets by using a Random Forest Algorithm.
OSCILLATION OF HYDROLOGICAL PARAMETERS IN SHRIMP PONDS WITHIN MANGROVE-DOMINATED INDIAN SUNDARBANS
Authors: Samanta Suvadeep
Published: September 2023

The survival rate of Penaeus monodon was monitored for a decade (2010-2019) in two shrimp culture ponds at Chemaguri located at Sagar Island in the Indian Sundarbans delta complex. The two ponds exhibited significant variations in terms of the survival rate of the cultured species, which is attributed to variations in nitrate, phosphate, and dissolved oxygen. The root cause of such difference is related to variation in stocking density of the cultured species (10 PL20/m2 in pond 1 and 25 PL20/m2 in pond 2) which resulted in the generation of nutrients (except silicate) and alteration of Dissolved Oxygen (DO). Optimization of stocking density and introduction of a biotreatment pond may restore and ecologically balance the situation in the shrimp culture sector of the Sundarban region.
METODE PENGGARAPAN MUSIK ILUSTRASI THE SOUND OF CRUSADES
Authors: Widianto M. Iqbal , Emridawati Emridawati , HR Hafif
Published: September 2023

The Sound of Crusades merupakan sebuah komposisi musik ilustrasi yang dibuat untuk mengekspresikan dan menghadirkan suasana perang salib melalui musik kepada para pendengarnya. Penggarapan komposisi ini berasal dari peristiwa perang salib, yaitu perang agama antara umat Islam dengan Kristen Eropa selama dua abad (akhir abad ke-11 sampai abad ke-13). Musik ini diolah dengan menggunakan perangkat elektronik seperti; hardware dan software untuk memproduksi musik multimedia, diantaranya; komputer, speaker monitor, midi controller, headset monitor, software Digital Audio Workstation, Virtual Studio Technology dan Virtual Studio Technology Instrument serta fitur Automation, Velocity dan Fx. Musik ini tergolong musik programa, dimana di dalamnya terdapat adegan dan cerita dengan visual slide gambar. Komposisi musik ini dibagi menjadi tiga bagian sesuai dengan alur cerita yang terjadi pada perang salib. Hasil akhir dari komposisi musik ilustrasi ini, berupa visualisasi video yang berisikan slide ilustrasi gambar perang salib.
JALUAR GANJIAL MUSIK DENGAN PENDEKATAN RE- INTERPRETASI TRADISI
Authors: Sukma Dio Puja , Yurnalis Yurnalis , Elizar Elizar
Published: September 2023

Karya komposisi musik ini bersumber dari Repertoar Kendidi yang terdapat pada Kesenian Celempong Rarak Godang di Kabupaten Kuantan Singingi, setelah pengkarya melakukan analisa terhadap Repertoar Kendidi tersebut pengkarya menemukan adanya perbedaan dua birama atau dissebut dengan Poly meter yang terdapat pada frase pertama pada repertoar Kendidi. Perbedaan birama itu lah yang menjadi ketertarikan pengkarya untuk ditafsirkan kembali ke dalam bentuk komposisi musik dengan judul “Jaluar Ganjial”, dalam penggarapannya pengkarya lebih cenderung menggunakan beberapa teknik garap seperti : permainan tempo, call and repons, unisoso, hocketting, sehingga terjadi permainan poly meter
PEMERANAN TOKOH GARENG DALAM NASKAH PENJUAL BENDERA KARYA WISRAN HADI DENGAN METODE STANISLAVSKY
Authors: Fajar Muhammad
Published: September 2023

Pemeran tokoh Gareng dalam naskah Penjual Bendera karya Wisran Hadi merupakan penciptaan seni peran yang dilakukan untuk mewujudkan tokoh Gareng pada sebuah pertunjukan diatas panggung. Penciptaan pemeran tersebut diawali dengan analisis naskah sesuai dengan tokoh yang akan di perankan. Bagian dari analisis tokoh Gareng meliputi aspek Psikologi, Fsiologi, Sosiologi. Hasil dari analisis tersebut menjadi pedoman bagi pemeran untuk mewujudkan tokoh Gareng, dengan menggunakan metode Akting Stanislavsky. Disini pemeran menggunakan Magic If atau Pengandaiaan yang berguna bagi pemeran untuk membangun bentuk keaktoran dan menyatukan karakter pemeran dengan karakter tokoh yang diperankan
PERTUNJUKAN SOLO PIANO REPERTOAR TOCCATA IN D MINOR BWV 565, PARTITA IN C MINOR BWV 826, MAK INANG PULAU KAMPAI
Authors: Haris Rizki Isman , Hendri Yon , Warhat Zainal
Published: September 2023

Pada penyajiannya, Toccata in D Minor BWV 565 yang merupakan salah satu karya popoler zaman barok yang diciptakan oleh J.S Bach pada kisaran tahun 1730-1735. Karya ini banyak mengandung Chord  dengan interval diminis yang dimainkan dalam bentuk Broken Chord dan penggandaan nada yang selaras dengan jarak satu oktave yang dimainkan dengan tempo cepat. Pada tahun 1899 Ferruccio Busoni menulis transkrip Toccata in D Minor BWV 565 kebentuk solo piano. Partita No. 2in C Minor BWV 826 adalah sebuah karya yang ditulis oleh J.S Bach untuk solo Harpsikord, karya ini ditulis pada tahun 1726. Partita adalah karya instrumental multi gerakan yang isinya beberapa gerakan yang relatif singkatyang di awali dengan Sinfonia.Sinfonia dimainkan dengan pengembangan dari Broken Chord pada tangan kanan dan diringi dengan glissando pada tangan kiri yang dimainkan pada tempo Gruve Adagio. Gerakan kedua dimainkan dengan not sepertigapuluhduaan dan seperenambelasan pada tangan kanan yang diringi dengan not seperdelapan tanpa jeda pada tangan kiri. Mak Inang Pulau Kampai adalah sebuah karya melayu dengan komposer NN yang diaransemen oleh Bapak Rizaldi S.Kar M. Hum kebentuk solo piano. Karya ini cukup populer di Indonesia dan juga di Malaysia. Kata “mak inang”artinya ialah pengasuh, jadi “mak inang” disini adalah seorang memiliki provesi sebagai pengasuh putra dan putri bangsawan pada zaman dahulu. Karya ini dimainkan dengan not seperenambelasan pada tangan kanan dan diringi dengan not seperdelapan yang menyerupai pola ritme Bass pada tangan kiri, dimainkan dengan tempo cepat dan memberikan suasana ceria senang, bahagia, damai dan tenang bagaikan ombak Pulau Kampai, sebuah pulau yang terletak di Muara sungai Besitang yang menghadap ke Selat Malaka.Kata kunci : Solo Piano; Pertunjukan; Klasik; Modern.
KOMPOSISI TARI DI BAWAH 35°C KLASIFIKASI GEJALA HIPOTERMIA DALAM PENGGARAPAN TARI TUNGGAL KONTEMPORER
Authors: Putri Dini Indah , Riswani Riswani , Syahril Syahril
Published: September 2023

Karya tari ini berjudul Di Bawah 35°C terinspirasi dari sebuah fenomena yang dialami oleh penanjak gunung yaitu hipotermia. Hipotermia adalah keadaan suhu tubuh yang turun di bawah 35°C yang menyebabkan fungsi sistem saraf dan organ tubuh lainnya mengalami gangguan. Gejala yang terjadi pada penderita hipotermia yang menjadi ketertarikan dan fokus pada karya ini. Untuk menggarap konsep menjadi sebuah karya tari maka pengkarya meggunakan salah satu metode untuk penggarapan karya yaitu pengumpulan data atau observasi, pengolahan data, studi pustaka, eksplorasi, penataan gerak, improvisasi, pembentukan dan evaluasi melalui konsep pendekatan inovasi dan interpretasi. Karya Di Bawah 35°C terdapat tiga bagian. yaitu bagian pertama hipotermia dengan klasifikasi ringan dengan gerak bergetar dengan postur mengecil atau menringkuk menggunakan musik iringan suara angin dan piano, bagian dua hipotermia dengan klasifikasi sedang, tubuh kaku, postur tubuh tegang dengan tenaga yang kuat menggunakan musik pengiring suara hujan, petir dan cello, pada bagian tiga yaitu hipotermia dengan klasifikasi berat, kesulitan bernafas, menggunakan gerak-gerak kontrek menggunakan musik iringan suara elektrocardiogram, alunan suara wanita, dan suara angin. Karya ini di pertunjukkan di pentas arena gedung Boestanul Arifin Adam dan menggunakan rias cantik panggung melalui rias korektif dengan kostum jaket bulu berwarna ungu, baju kaos turtleneck berwarna ungu, celana cargo panjang berwarna hitam, sarung tangan berwarna hitam, kaos kaki berwarna hitam mengkilap dan ungu. Kata kunci : Gejala, hipotermia, klasifikasi.