bluuebunny/crossref_metadata_2025 huggingface dataset:
Extensive and Intensive Agricultural Supply Response
Authors: Babcock Bruce A.
Published: June 2015

Interest in agricultural supply response increased dramatically after model predictions of land use change were used to estimate biofuel greenhouse gas emissions. The models divide crop response into higher yield—the intensive margin—or more land—the extensive margin. Input adjustments are assumed to drive yield response. But most yield changes result from adoption of technology. Regulators and modelers assume that increased harvested area implies conversion of land from forest or pasture to crops. With the notable exception of African countries, recent expansion of harvested area is due to more intensive use of existing agricultural land through multiple cropping and technology improvement. A lack of response at the extensive margin is consistent with inelastic estimates of land use change estimated by using time-series data. Option value is one reason for this inelastic response. Predictions of land use change based on cross-section data imply much higher land use elasticities than are consistent with recent data.
Separating the roles of nitrogen and oxygen in high pressure-induced blood-borne microparticle elevations, neutrophil activation, and vascular injury in mice
Authors: Yang Ming , Bhopale Veena M. , Thom Stephen R.
Published: June 2015

An elevation in levels of circulating microparticles (MPs) due to high air pressure exposure and the associated inflammatory changes and vascular injury that occur with it may be due to oxidative stress. We hypothesized that these responses arise due to elevated partial pressures of N2 and not because of high-pressure O2. A comparison was made among high-pressure air, normoxic high-pressure N2, and high-pressure O2 in causing an elevation in circulating annexin V-positive MPs, neutrophil activation, and vascular injury by assessing the leakage of high-molecular-weight dextran in a murine model. After mice were exposed for 2 h to 790 kPa air, there were over 3-fold elevations in total circulating MPs as well as subgroups bearing Ly6G, CD41, Ter119, CD31, and CD142 surface proteins—evidence of neutrophil activation; platelet-neutrophil interaction; and vascular injury to brain, omentum, psoas, and skeletal muscles. Similar changes were found in mice exposed to high-pressure N2 using a gas mixture so that O2 partial pressure was the same as that of ambient air, whereas none of these changes occurred after exposures to 166 kPa O2, the same partial pressure that occurs during high-pressure air exposures. We conclude that N2 plays a central role in intra- and perivascular changes associated with exposure to high air pressure and that these responses appear to be a novel form of oxidative stress.
Identification of Oncogenic and Drug-Sensitizing Mutations in the Extracellular Domain of FGFR2
Authors: Tanizaki Junko , Ercan Dalia , Capelletti Marzia , Dodge Michael , Xu Chunxiao , Bahcall Magda , Tricker Erin M. , Butaney Mohit , Calles Antonio , Sholl Lynette M. , Hammerman Peter S. , Oxnard Geoffrey R. , Wong Kwok-Kin , Jänne Pasi A.
Published: June 2015

The discovery of oncogenic driver mutations and the subsequent developments in targeted therapies have led to improved outcomes for subsets of lung cancer patients. The identification of additional oncogenic and drug-sensitive alterations may similarly lead to new therapeutic approaches for lung cancer. We identify and characterize novel FGFR2 extracellular domain insertion mutations and demonstrate that they are both oncogenic and sensitive to inhibition by FGFR kinase inhibitors. We demonstrate that the mechanism of FGFR2 activation and subsequent transformation is mediated by ligand-independent dimerization and activation of FGFR2 kinase activity. Both FGFR2-mutant forms are predominantly located in the endoplasmic reticulum and Golgi but nevertheless can activate downstream signaling pathways through their interactions with fibroblast growth factor receptor substrate 2 (FRS2). Our findings provide a rationale for therapeutically targeting this unique subset of FGFR2-mutant cancers as well as insight into their oncogenic mechanisms. Cancer Res; 75(15); 3139–46. ©2015 AACR.
Using CellMiner 1.6 for Systems Pharmacology and Genomic Analysis of the NCI-60
Authors: Reinhold William C. , Sunshine Margot , Varma Sudhir , Doroshow James H. , Pommier Yves
Published: June 2015

The NCI-60 cancer cell line panel provides a premier model for data integration, and systems pharmacology being the largest publicly available database of anticancer drug activity, genomic, molecular, and phenotypic data. It comprises gene expression (25,722 transcripts), microRNAs (360 miRNAs), whole-genome DNA copy number (23,413 genes), whole-exome sequencing (variants for 16,568 genes), protein levels (94 genes), and cytotoxic activity (20,861 compounds). Included are 158 FDA-approved drugs and 79 that are in clinical trials. To improve data accessibility to bioinformaticists and non-bioinformaticists alike, we have developed the CellMiner web–based tools. Here, we describe the newest CellMiner version, including integration of novel databases and tools associated with whole-exome sequencing and protein expression, and review the tools. Included are (i) “Cell line signature” for DNA, RNA, protein, and drugs; (ii) “Cross correlations” for up to 150 input genes, microRNAs, and compounds in a single query; (iii) “Pattern comparison” to identify connections among drugs, gene expression, genomic variants, microRNA, and protein expressions; (iv) “Genetic variation versus drug visualization” to identify potential new drug:gene DNA variant relationships; and (v) “Genetic variant summation” designed to provide a synopsis of mutational burden on any pathway or gene group for up to 150 genes. Together, these tools allow users to flexibly query the NCI-60 data for potential relationships between genomic, molecular, and pharmacologic parameters in a manner specific to the user's area of expertise. Examples for both gain- (RAS) and loss-of-function (PTEN) alterations are provided. Clin Cancer Res; 21(17); 3841–52. ©2015 AACR.
FDA Approval Summary: Ramucirumab for Gastric Cancer
Authors: Casak Sandra J. , Fashoyin-Aje Ibilola , Lemery Steven J. , Zhang Lillian , Jin Runyan , Li Hongshan , Zhao Liang , Zhao Hong , Zhang Hui , Chen Huanyu , He Kun , Dougherty Michele , Novak Rachel , Kennett Sarah , Khasar Sachia , Helms Whitney , Keegan Patricia , Pazdur Richard
Published: June 2015

The FDA approved ramucirumab (CYRAMZA; Eli Lilly and Company) for previously treated patients with advanced or metastatic gastric or gastroesophageal junction adenocarcinoma initially as monotherapy (April 21, 2014) and subsequently as combination therapy with paclitaxel (November 5, 2014). In the monotherapy trial, 355 patients in the indicated population were randomly allocated (2:1) to receive ramucirumab or placebo, 8 mg/kg intravenously every 2 weeks. In the combination trial, 665 patients were randomly allocated (1:1) to receive ramucirumab or placebo, 8 mg/kg intravenously every 2 weeks, in combination with paclitaxel, 80 mg/m2 on days 1, 8, and 15 of 28-day cycles. Overall survival (OS) was increased in patients who received ramucirumab in both the monotherapy [HR, 0.78; 95% confidence interval (CI), 0.60–0.998; log rank P = 0.047] and combination trials (HR, 0.81; 95% CI, 0.68–0.96; P = 0.017). The most common adverse reactions were hypertension and diarrhea in the monotherapy trial and fatigue, neutropenia, diarrhea, and epistaxis in the combination trial. Because of concerns about the robustness of the monotherapy trial results, FDA approved the original application after receiving the results of the combination trial confirming the OS effect. Based on exploratory exposure–response analyses, there is residual uncertainty regarding the optimal dose of ramucirumab. Clin Cancer Res; 21(15); 3372–6. ©2015 AACR.
Melanoma Induces, and Adenosine Suppresses, CXCR3-Cognate Chemokine Production and T-cell Infiltration of Lungs Bearing Metastatic-like Disease
Authors: Clancy-Thompson Eleanor , Perekslis Thomas J. , Croteau Walburga , Alexander Matthew P. , Chabanet Tamer B. , Turk Mary Jo , Huang Yina H. , Mullins David W.
Published: June 2015

Despite immunogenicity, melanoma-specific vaccines have demonstrated minimal clinical efficacy in patients with established disease but enhanced survival when administered in the adjuvant setting. Therefore, we hypothesized that organs bearing metastatic-like melanoma may differentially produce T-cell chemotactic proteins over the course of tumor development. Using an established model of metastatic-like melanoma in lungs, we assessed the production of specific cytokines and chemokines over a time course of tumor growth, and we correlated chemokine production with chemokine receptor–specific T-cell infiltration. We observed that the interferon (IFN)-inducible CXCR3-cognate chemokines (CXCL9 and CXCL10) were significantly increased in lungs bearing minimal metastatic lesions, but chemokine production was at or below basal levels in lungs with substantial disease. Chemokine production was correlated with infiltration of the organ compartment by adoptively transferred CD8+ tumor antigen-specific T cells in a CXCR3- and host IFNγ-dependent manner. Adenosine signaling in the tumor microenvironment (TME) suppressed chemokine production and T-cell infiltration in the advanced metastatic lesions, and this suppression could be partially reversed by administration of the adenosine receptor antagonist aminophylline. Collectively, our data demonstrate that CXCR3-cognate ligand expression is required for efficient T-cell access of tumor-infiltrated lungs, and these ligands are expressed in a temporally restricted pattern that is governed, in part, by adenosine. Therefore, pharmacologic modulation of adenosine activity in the TME could impart therapeutic efficacy to immunogenic but clinically ineffective vaccine platforms. Cancer Immunol Res; 3(8); 956–67. ©2015 AACR.
Feasibility of the Ultrasonic Bone Aspirator in Retrosigmoid Vestibular Schwannoma Removal
Authors: Golub Justin S. , Weber Jon D. , Leach James L. , Pottschmidt Natalie R. , Zuccarello Mario , Pensak Myles L. , Samy Ravi N.
Published: June 2015

Objective:

Postoperative headache is an undesirable consequence of retrosigmoid vestibular schwannoma (VS) removal. An ultrasonic bone aspirator (UBA) may reduce headache by minimizing subarachnoid bone dust dispersion. The feasibility of removing internal auditory canal (IAC) bone with a UBA is unknown. This study assessed volume and duration of IAC bone removal in clinical and laboratory settings.

Study Design:

(1) Retrospective review of radiologic data and intraoperative videos. (2) Cadaveric temporal bone model.

Setting:

(1) Tertiary care medical center. (2) Laboratory.

Subjects Methods:

We calculated the volume of IAC bone drilled during retrosigmoid VS removal using postoperative computed tomography scans. We then measured the time spent actively drilling IAC bone by analyzing operative videos. Finally, we measured bone ablation rates in a cadaveric temporal bone model using a drill and UBA.

Results:

The mean ± SD volume of IAC bone removed during surgery was 0.32 ± 0.17 mL (n = 9). The time spent actively removing IAC bone with a drill was only 10.4 ± 3.5 minutes, less than a third of the total IAC opening time of 34.2 ± 13.1 minutes (n = 5). On cadaveric specimens, the UBA removed bone at 0.21 ± 0.03 or 0.35 ± 0.07 µL/s at 15% or 50% power, respectively (n = 4). This extrapolates to 15.0 ± 3.0 to 25.0 ± 3.9 minutes to remove the same 0.32 mL from surgery.

Conclusions:

The volume and duration of IAC bone removal during retrosigmoid VS surgery are small. Using a UBA at low power instead of a drill would extend the length of surgery by 5 to 15 minutes, with the theoretical potential for reducing headache.
High performance chrome free coating for white rust protection of zinc
Authors: Bera S. , Udayabhanu G. , Narayan R. , Rout T. K.
Published: June 2015

Development of chrome free coatings for white rust (corrosion) protection of galvanised steel is a key concern for scientists worldwide. The present work presents the results of an investigation on the effect of amine and thiol functional groups bearing silane coupling agents such as 3-phenyl-aminopropyl-triethoxy silane and mercapto-propyl-tri methoxysilane respectively on anticorrosion properties of a reference sol–gel solution. Anticorrosion performance of the coatings was evaluated by potentiodynamic polarisation method and AC impedance spectroscopy. Accelerated corrosion test was performed using salt spray chamber and compared with a chromate coated galvanised sheet. The results clearly revealed that the addition of silane containing thiol group to the reference coating solution produced remarkable improvement in hydrophobicity and corrosion resistance compared to amine group.
Mucin 1 is a potential therapeutic target in cutaneous T-cell lymphoma
Authors: Jain Salvia , Stroopinsky Dina , Yin Li , Rosenblatt Jacalyn , Alam Maroof , Bhargava Parul , Clark Rachael A. , Kupper Thomas S. , Palmer Kristen , Coll Maxwell D. , Rajabi Hasan , Pyzer Athalia , Bar-Natan Michal , Luptakova Katarina , Arnason Jon , Joyce Robin , Kufe Donald , Avigan David
Published: June 2015

Key Points

MUC1-C oncoprotein contributes toward maintenance of redox balance in CTCL. Targeting the MUC1-C oncoprotein in CTCL cells induces ROS-mediated death highlighting its potential as an effective strategy.
Severe but not mild hypercapnia affects the outcome in patients with severe cardiogenic pulmonary edema treated by non-invasive ventilation
Authors: Contou Damien , Fragnoli Chiara , Córdoba-Izquierdo Ana , Boissier Florence , Brun-Buisson Christian , Thille Arnaud W
Published: June 2015

Background

Patients with severe cardiogenic pulmonary edema (CPE) are frequently hypercapnic, possibly because of associated underlying chronic lung disease (CLD). Since hypercapnia has been associated with outcome, we aimed to identify factors associated to hypercapnia and its role on outcome of patients with CPE and no underlying CLD.

Methods

Observational cohort study using data prospectively collected over a 3-year period. After excluding patients with any CLD or obstructive sleep apneas, all patients treated by non-invasive ventilation (NIV) for severe CPE were included. Hypercapnia was defined as PaCO2 >45 mmHg and non-rapid favorable outcome was defined as the need for intubation or continuation of NIV for more than 48 h.

Results

After excluding 60 patients with underlying CLD or sleep apneas, 112 patients were studied. The rates of intubation and of prolonged NIV were 6.3 % (n = 7) and 21.4 % (n = 24), respectively. Half of the patients (n = 56) had hypercapnia upon admission. Hypercapnic patients were older, more frequently obese, and were more likely to have a respiratory tract infection than non-hypercapnic patients. Hypercapnia had no influence on intubation rate or the need for prolonged NIV. However, patients with severe hypercapnia (PaCO2 >60 mmHg) needed longer durations of NIV and intensive care unit (ICU) stay than the others.

Conclusions

Among the patients admitted for severe CPE without CLD, half of them had hypercapnia at admission. Hypercapnic patients were older and more frequently obese but their outcome was similar compared to non-hypercapnic patients. Patients with severe hypercapnia needed longer durations of NIV than the others without increase in intubation rate.
The poorly known genus Ventrifurca Roewer, 1913 revisited (Opiliones: Cranaidae)
Authors: Villarreal M Osvaldo , Kury Adriano B , Pinto-da-Rocha Ricardo
Published: June 2015

Background

The distinction of genera in Cranaidae (as in many other Gonyleptoidea) is traditionally made on the basis of a combination of armature of scutal areas, tarsomere counts, and some secondary sexual structures (which may vary among males). This historically led to the creation of non-natural groups of species as meaningless genera. Here some nominal genera of Cranaidae are addressed, and this paucity of diagnostic characters is alleviated with more detailed diagnoses and descriptions.

Results

The poorly known genusVentrifurcaRoewer, 1913, hitherto monotypic, is revisited. The generaMicrocranausRoewer, 1913 (with three species),CayabeusRoewer, 1932 (monotypic), andAngistrius(monotypic) are here proposed as junior subjective synonyms ofVentrifurca. Both type species ofMicrocranausandCayabeusare considered junior subjective synonyms ofVentrifurca albipustulata; thus,Cayabeus perlatusRoewer, 1932 andMicrocranaus pustulatusRoewer, 1913 = Ventrifurca albipustulataRoewer, 1913.Ventrifurca abnormiscomb. nov. is proposed forAngistrius abnormisRoewer, 1932.Rhopalocranaus dybasiGoodnight & Goodnight, 1947, currentlyNeocranaus dybasi, is transferred toVentrifurca, and the new combinationVentrifurca dybasicomb. nov. is herein proposed for it.Ventrifurca albipustulatais redescribed, and for the first time, the male genitalia is described and illustrated, and SEM pictures are offered. The new speciesVentrifurca caffeinicasp. nov. is described from Quindío department, Colombia. A new diagnosis toVentrifurcais proposed. The relationships ofVentrifurcaare discussed. The remaining two species ofMicrocranausare transferred to the family Manaosbiidae: (1)Microcranaus columbianusnewly combined asRhopalocranaus columbianus(Roewer, 1963) and (2)Microcranaus gracilisnewly combined asCamelianus gracilis(Roewer, 1913). New diagnoses are given for both species.

Conclusions

A non-monotypic genus of Andean Cranaidae is defined, associated with a well-defined geographic region, and unloaded of extraneous species which belong to another family. Recognition of variation in heteromorphic males reveals past errors of assignment when only limited samples were available for study.
Fenologia e modos de polinização e dispersão de Fabaceae em floresta ciliar, Chapada Diamantina, Nordeste do Brasil
Authors: Souza Isys Mascarenhas , Funch Ligia Silveira
Published: June 2015

Phenological patterns have been described based on frequency, period and duration of the events and analyzed as a function of biotic and abiotic factors with the vegetative and reproductive cycles of plant species commonly related to the precipitation and day length. In this work, we describe the phenological strategies of 11 Fabaceae species present in gallery forests along the Lençóis River, Chapada Diamantina, Bahia State, Brazil, and investigate the environmental factors influence and pollination and dispersal modes on the phenological patterns. Observations of vegetative (leaf flushing and leaf fall) and reproductive (bud, flower, immature fruit and mature fruit) phenology were made among a group of 75 individuals based on Fournier index (24 months). Interspecific synchrony was determined based on the presence or absence of each phenophase in the individuals. Multiple linear regression analyses were conducted to investigate the influence of environmental variables on the phenophases, and Pearson correlation analysis between vegetative and reproductive events. Pollination and dispersal syndromes were defined based on field observations and literature. The species demonstrated non-seasonal vegetative and reproductive events, different of the expected for the family. However, the flowers and mature fruits (i.e., resources for pollinators and dispersal agents) were seasonal. The correlation with precipitation was positive to the leaf flush and negative to leaf fall and diaspore propagation. The leaf flushing, flowering and fruit maturation are correlated to day length. Our study reveals the occurrence of different groups of Fabaceae with distinct flowering and fruiting peaks related to pollination and dispersal syndromes, which minimize the niche overlapping among them.
Lipid Profiles of Adipose and Muscle Tissues in Mouse Models of Juvenile Onset of Obesity without High Fat Diet Induction: A Fourier Transform Infrared (FT-IR) Spectroscopic Study
Authors: Sen Ilke , Bozkurt Ozlem , Aras Ebru , Heise Sebastian , Brockmann Gudrun Anni , Severcan Feride
Published: June 2015

The current study aims to determine lipid profiles in terms of the content and structure of skeletal muscle and adipose tissues to better understand the characteristics of juvenile-onset spontaneous obesity without high fat diet induction. For the purposes of this study, muscle (longissimus, quadriceps) and adipose (inguinal, gonadal) tissues of 10-week-old male DBA/2J and Berlin fat mouse inbred (BFMI) lines (BFMI856, BFMI860, BFMI861) fed with a standard breeding diet were used. Biomolecular structure and composition was determined using attenuated total reflection Fourier transform (ATR FT-IR) spectroscopy, and muscle triglyceride content was further quantifed using high-performance liquid chromatography (HPLC) coupled with an evaporative light scattering detector (ELSD). The results revealed a loss of unsaturation in BFMI860 and BFMI861 lines in both muscles and inguinal adipose tissue, together with a decrease in the hydrocarbon chain length of lipids, especially in the BFMI860 line in muscles, suggesting an increased lipid peroxidation. There was an increase in saturated lipid and triglyceride content in all tissues of BFMI lines, more profoundly in longissimus muscle, where the increased triglyceride content was quantitatively confrmed by HPLC-ELSD. Moreover, an increase in the metabolic turnover of carbohydrates in muscles of the BFMI860 line was observed. The results demonstrated that subcutaneous (inguinal) fat also displayed considerable obesity-induced alterations. Taken together, the results revealed differences in lipid structure and content of BFMI lines, which may originate from different insulin sensitivity levels of the lines, making them promising animal models for spontaneous obesity. The results will contribute to the understanding of the generation of insulin resistance in obesity without high fat diet induction.
Optical Absorption Measurements of Hydrogen Chloride at High Temperature and High Concentration in the Presence of Water Using a Tunable Diode Laser System for Application in Pyrohydrolysis Non-Ferrous Industrial Process Control
Authors: Tzanetakis Tommy , Susilo Robin , Wang Zhenyou , Padmanabhan Arathi , Davis Boyd R. , Thomson Murray J.
Published: June 2015

A tunable diode laser (TDL) was used to measure hydrogen chloride (HCl) spectra at 5747 cm−1 (1.74 μm) and temperatures of 25–950 °C in a quartz cell. The purpose was to evaluate the capability of monitoring HCl concentration under pyrohydrolysis conditions using a near-infrared (NIR) laser. These conditions are characterized by 20–40% HCl, 2–40% H2O, and the presence of metal chloride vapors at temperatures of 600–1000 °C. Spectral peak area measurements of HCl–N2 mixtures at atmospheric pressure and a path length of 8.1 cm showed linear absorption behavior between concentrations of 5–95% and temperatures of 25–950 °C. Results from the addition of 2–40% water (H2O) indicate that the HCl peak area relationships are not affected for temperatures of 350–950 °C. Evaporating NiCl2 within the cell did not show spectral interference effects with HCl between 650 and 850 °C. The results from this work indicate that a near-infrared optical sensor is capable of measuring high HCl concentrations at high temperatures in the presence of high H2O content during pyrohydrolysis process conditions.
Effect of the Solvent on the Size of Clay Nanoparticles in Solution as Determined Using an Ultraviolet–Visible (UV-Vis) Spectroscopy Methodology
Authors: Alin Jonas , Rubino Maria , Auras Rafael
Published: June 2015

Ultraviolet–visible (UV-Vis) spectroscopy methodology was developed and utilized for the in situ nanoscale measurement of the size of mineral clay agglomerates in various liquid suspensions. The clays studied were organomodified and unmodified montmorillonite clays (I.44p, Cloisite 93a, and PGN). The methodology was compared and validated against dynamic light scattering (DLS) analysis. The method was able to measure clay agglomerates in solvents in situations where DLS analysis was unsuccessful due to the shapes, polydispersity, and high aspect ratios of the clay particles and the complexity of the aggregates, or dispersion medium. The measured clay agglomerates in suspension were found to be in the nanometer range in the more compatible solvents, and their sizes correlated with the Hansen solubility parameter space distance between the clay modifiers and the solvents. Mass detection limits for size determination were in the range from 1 to 9 mg/L. The methodology thus provides simple, rapid, and inexpensive characterization of clays or particles in the nano- or microsize range in low concentrations in various liquid media, including complex mixtures or highly viscous fluids that are difficult to analyze with DLS. In addition, by combining UV-VIS spectroscopy with DLS it was possible to discern flocculation behavior in liquids, which otherwise could result in false size measurements by DLS alone.
What are you looking at?: Staring down notions of the disabled body in dance
Authors: Durham-Wall Meghan
Published: June 2015

This article considers the display of the disabled body in dance performance. I use Heidi Latsky’s Five Open Mouths as an example of how staging physical otherness can be an act of provocation that reframes conventional perceptions of the disabled dancing body. I draw on cultural critic Rosemarie Garland-Thomson’s construct of the ‘baroque stare’ as a prolonged and engaged visual encounter between seer and seen. Used productively in dance, this stare helps viewers recognize how they experience seeing and holds potential as a generative site for renegotiating social, cultural and aesthetic assumptions about the disabled body.
Waltzing disability culture: Moving history with Raimund Hoghe
Authors: Kuppers Petra
Published: June 2015

This article speaks about transmission and disability culture, and about a dance created by a disabled person, German choreographer Raimund Hoghe, in order to excavate something lost: disability culture’s history, disabled people’s sense of a particular history that pertains to them and that puts their unique embodiment and enmindment into a wider temporal perspective. Waltzing and turning are dancerly metaphors throughout this article, ways in which language and movement join in dance work about that which has vanished.
Validation and virtuosity: Perspectives on difference and authorship/control in dance
Authors: Whatley Sarah , Waelde Charlotte , Brown Abbe , Harmon Shawn
Published: June 2015

This article brings together two different perspectives, dance and law, to ask questions about authorship and ownership in disabled dance. The focus is on Caroline Bowditch’s short film project, A Casting Exploration, in which she is recast as the female dancer in a duet section from Joan Cleville’s choreography for Scottish Dance Theatre, Love Games. We explore what medical law, human rights law and intellectual property law might say about Bowditch’s role. We show how the film project raises questions about the aesthetic properties of the double duet, the politics of sameness and difference, and who can claim ‘ownership’ of the dance.
Disabling ability in dance: Intercultural dramaturgies of the Thikwa plus Junkan Project
Authors: Nakajima Nanako
Published: June 2015

From 2008 to 2012, I worked as a dramaturge in Japan and Germany, developing an international dance project titled Thikwa plus Junkan Project with Osamu Jareo, a choreographer based in Japan. This project, involving Japanese and German differently abled performers, was created and performed in both countries. This article highlights our experiences while designing and implementing this mixed-ability, intercultural project. Stretching across disciplines and code systems, this project reveals cultural construction of dis/ability and dance aesthetics and provides an alternative concept for dancing bodies. To avoid using the other culture for one’s own benefit as well as to avoid being consumed as its others in the international dance market, I consider, in this article, how the intercultural dramaturgy of this project aims to realize a cultural ecology of dance by switching our cultural frames to balance the power.
Simon Hantaï Editorial
Authors: Finch Mick , Lisbon Laura , Sturgis Daniel
Published: June 2015

Simon Hantaï’s reputation was established from the early 1960s, with regular exhibitions up until his withdrawal from the art world in 1982. His work had a consistent impact in France where he is regarded as a major post-war artist who initiated a crucial rethinking of painting in the wake of Pollock and Matisse, influencing most specifically the generation epitomized by the groups Buren, Mosset, Parmentier and Toroni and Supports/Surfaces. More recently, however, an exhibition at the Paul Kasmin Gallery in New York (2010) and a major retrospective at the Centre Pompidou in Paris (2013) have contributed to a growing interest in, and recognition of, Hantaï’s work outside of France. This issue of the Journal of Contemporary Painting is an intervention within this emerging reception.
Simon Hantaï’s personal archives
Authors: Hantaï Anna
Published: June 2015

This article deals with the results of a preliminary catalogue of Simon Hantaï’s wonderfully rich collection of personal archives, left untouched in his studio at the time of his death. From 1984, as he voluntarily withdrew from the artistic scene and the public arena, Hantaï never actually ceased working. In the last fifteen years of his life, when he was particularly active, a large part of the work archived was created or else collected, manipulated and reused. These archives are part and parcel of Hantaï’s original creative process at the time, as he reassessed and continued his work.
Contemporary responses to the work of Simon Hantaï by Andy Harper, Marjorie Welish, Joe Fyfe, Amélie De Beauffort and Stuart Elliot
Authors: Lisbon Laura , Harper Andy , Welish Marjorie , Fyfe Joe , Beauffort Amélie de , Elliot Stuart
Published: June 2015

The Journal of Contemporary Painting invited five contemporary artists to reflect on the work of Simon Hantaï. Reflections by British artists, Stuart Elliot and Andy Harper; Belgian artist, Amelie de Beauffort; and American artists, Joe Fyfe and Marjorie Welish, are collected here. Each artist wrote from a different proximity to the work of Simon Hantaï – through seeing the work in recent exhibitions or catalogues – but always grounded by engagements with their own studio practices. A brief introduction by Laura Lisbon offers a glimpse at one of the many provocations that Hantaï’s work offers through viewing in person the major retrospective exhibition at the Centre Pompidou, Paris, in 2013. The viewing of the exhibition acted as the initial prompt to invite contemporary artists to reflect on Simon Hantaï at this point in time. The artists’ reflections collected here explore insights into the aleatory, temporal, topological and historical dimensions of Hantaï’s work.
The Effects of Team-Based Learning on Students’ Attitudes and Students’ Performances in Introductory Sociology Classes
Authors: Killian Mark , Bastas Hara
Published: June 2015

Relevant in many academic contexts, recent scholarship in sociology has challenged departments to improve the public face of the discipline through introductory classes. However, this scholarship has not addressed how departments can improve the discipline’s public face while maintaining student performance. It is one thing to create an engaging introductory class; it is another to create an engaging introductory class that ensures student learning. One way to possibly achieve the latter is to implement innovative instructional methods that promote active learning. As documented in various fields, one such method is Team-Based Learning (TBL), an active-learning strategy that uses student groups to teach concepts and their applications. Literature has highlighted the success of TBL on students’ perceptions of classes, but reported ambiguous results concerning improved students’ performances. In this article we deviate from previous research, by examining the effect of TBL on students’ attitudes toward sociology (e.g. the public face of the discipline) as well as students’ performances. Results indicate that, as opposed to lecture-based classes, students in TBL classes have much more positive attitudes toward the discipline, while demonstrating equivalent performances. Consequently, we argue that, as long as students’ performances are maintained, academic departments should put time and effort into converting introductory courses into environments of active learning in order to improve the discipline’s public face.
Instructional Internships: Improving the teaching and learning experience for students, interns, and faculty
Authors: Hemmerich Abby L. , Hoepner Jerry K. , Samelson Vicki M.
Published: June 2015

Students training for clinical careers must acquire skills for teaching clients, their families, and fellow professionals. Guidelines for training programs in Communication Sciences and Disorders (Speech-Language Pathology), however, do not currently include standards for pedagogy. The aim of this study was to measure changes in undergraduate students' perceptions of teaching and learning following an Instructional Internship experience, where they served as teaching assistants for foundational knowledge courses in the major. Using a qualitative research design, we coded 31 participants' statements from pre- and post-internship essays and identified major themes and sub-themes.                Our results indicate that by participating in a teaching experience, students develop a deeper appreciation for the relationships between classroom pedagogy, their own learning, and clinical practice. While this study focuses on a pedagogical experience for undergraduate students in a Communication Sciences and Disorders program, the principles and results are generalizable to other professions that train students to provide clinical and educational services.Keywords: teaching assistants, instructional interns, mentoring, doctoral shortage, undergraduates
The effects of acute hyperinsulinemia on bone metabolism
Authors: K Ivaska Kaisa , K Heliövaara Maikki , Ebeling Pertti , Bucci Marco , Huovinen Ville , Kalervo Väänänen H , Nuutila Pirjo , A Koistinen Heikki
Published: June 2015

Insulin signaling in bone-forming osteoblasts stimulates bone formation and promotes the release of osteocalcin (OC) in mice. Only a few studies have assessed the direct effect of insulin on bone metabolism in humans. Here, we studied markers of bone metabolism in response to acute hyperinsulinemia in men and women. Thirty-three subjects from three separate cohorts (n=8, n=12 and n=13) participated in a euglycaemic hyperinsulinemic clamp study. Blood samples were collected before and at the end of infusions to determine the markers of bone formation (PINP, total OC, uncarboxylated form of OC (ucOC)) and resorption (CTX, TRAcP5b). During 4 h insulin infusion (40 mU/m2 per min, low insulin), CTX level decreased by 11% (P<0.05). High insulin infusion rate (72 mU/m2 per min) for 4 h resulted in more pronounced decrease (−32%, P<0.01) whereas shorter insulin exposure (40 mU/m2 per min for 2 h) had no effect (P=0.61). Markers of osteoblast activity remained unchanged during 4 h insulin, but the ratio of uncarboxylated-to-total OC decreased in response to insulin (P<0.05 and P<0.01 for low and high insulin for 4 h respectively). During 2 h low insulin infusion, both total OC and ucOC decreased significantly (P<0.01 for both). In conclusion, insulin decreases bone resorption and circulating levels of total OC and ucOC. Insulin has direct effects on bone metabolism in humans and changes in the circulating levels of bone markers can be seen within a few hours after administration of insulin.
Prey suitability of Tuta absoluta larvae (Lepidoptera: Gelechiidae) for three predatory phytoseiid mites (Acari: Phytoseiidae) under laboratory conditions
Authors: Metwally A. M. , Momen F. M. , Nasr A. K. , Abdallah A. A. , Ebadah I. M. , Saleh Kh. M.
Published: June 2015

Tomato crop in the Mediterranean Basin has been recently affected by the exotic pest Tuta absoluta (Meyrick), which is difficult to control due to its high reproduction rate and potential to develop resistance to insecticides. In this paper, the suitability and effectiveness of three predatory phytoseiid mites Cydnoseius negevi (Swirski and Amitai), Neoseiulus barkeri (Hughes) and Amblyseius largoensis (Muma), an indigenous species, were evaluated on larvae of T. absoluta under laboratory conditions. First instar larvae of T. absoluta proved to be possible food source for tested phytoseiid mites under laboratory conditions.

Females of C. negevi, A. largoensis and N. barkeri were able to feed and sustain oviposition on unfed, first instar larvae of T. absoluta. A diet of insect larvae provided the shortest oviposition period and adult longevity of C. negevi and A. largoensis, while N. barkeri showed the longest corresponding periods. The total and daily number of insect larvae consumed was significantly higher in N. barkeri than in A. largoensis and C. negevi. Likewise, N. barkeri laid significantly higher number of eggs (23.6 eggs / female) than that deposited by C. negevi and A. largoensis (2.5 and 3.9 eggs / female). The sex ratio of the progeny was female biased and ranged: (females / total=0.62-0.68%) when insect larvae were provided for females of C. negevi, A. largoensis and N. barkeri.
Emergence of new virulence in Plasmopara halstedii (sunflower downy mildew)
Authors: Sakr N.
Published: June 2015

The fast evolution of Plasmopara halstedii (downy mildew) remains a major risk for sunflower crop, as new races of the pathogen are bypassing the resistance of sunflower hybrids. In order to understand the processes which led a new virulence to appear in a local P. halstedii population, the genetic relationships were studied using 12 EST (Expressed Sequence Tag)-derived markers between five progeny isolates of races 300, 304, 314, 704 and 714 and two parental ones of races 100 and 710. All genetic analyses were carried out using five single zoosporangium isolates per P. halstedii isolate. There was no intra-isolate genetic variation among the seven pathogen isolates and five multilocus genotypes (MLG) were identified among the 35 P. halstedii single zoosporangium isolates. The single zoosporangium isolates of races 314, 704 and 714 had an intermediary genetic position between the single zoosporangium isolates of two parental isolates. The single zoosporangium isolates of three isolates of races 100, 300 and 304 were localized in the same genetic clade. Two genetic mechanisms could explain the emergence of new virulence in P. halstedii as a recombination between races and mutations in a clonal lineage.
Brachycaudus species on herbaceous plants along highways in Hungary
Authors: Basky Zs.
Published: June 2015

Survey of aphids on dicotyledonous herbaceous plants along the Hungarian highways on 33 sampling points revealed the presence of four holocyclic Brachycaudus species. The monoecious B. lychnidis L. 1758 was the most frequently collected species. It colonised the perennial Silene alba (Mill.) E. H. L. Krause 1893 on the youngest highway section around Budapest (5 locations). The frequency of this species is due to frequent occurrence of its host plant on this section compared to other host species. New record for the Hungarian fauna is the occurrence of monoecious B. setosus Hille Ris Lambers 1948 on the biennial or perennial Tragopogon orientalis L. 1753 on two locations on the southern part of the country. The heteroecious B. cardui L. 1758 was found on biennial or perennial Senecio jacobaea L. 1753 in one location on north-western part of Hungary. On the north-eastern part of the country the perennial Symphytum officinale subsp. bohemicum (F. W. Schmidt) Čelak 1891 occurred on a damp area. The monoecious B. mordvilkoi Hille Ris Lambers 1931 colonised this Boraginaceae species.
Monitoring and testing different doses of disparlure for Indian gypsy moth, Lymantria obfuscata, in a temperate region of India (Kashmir Valley)
Authors: Hussain B. , War A. R. , Ganie S. A. , Bilal S.
Published: June 2015

Pheromone traps with different doses of disparlure [(Z)-7,8-epoxy-2-methyloctadecane] were tested for a local strain of the Indian gypsy moth (Lymantria obfuscata) at Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir (India). Disparlure at 500 µg dose proved to be effective in trapping gypsy moth populations. The first adults were caught on the third week of June in 2007-2009 with peak catches a week later. Catches in disparlure-baited traps at all dosage levels (0.5, 50 and 500 µg) were significantly higher as compared to control traps. The regression equation revealed strong (99%) correlation between moth catches and applied doses. The accumulated degree day model predicted 65.31 to 117.97 heat units for larval hatch and 794.66 to 928.15 heat units for adult emergence. The principal component analysis showed significant variability between weather variables and adult L. obfuscata population.
Location and locatum verbs revisited: Evidence from aspect and quantification
Authors: Acedo-Matellán Víctor , Real-Puigdollers Cristina
Published: June 2015

In this paper we claim that location and locatum verbs are grammatically different, contrary to some recent analyses (Mateu 2001; 2008; Harley 2005). While aspectual tests are known to distinguish both classes, we adduce new evidence from degree quantification tests pointing in the same direction. In particular, location verbs seem to be change-of-state verbs, and locatum verbs behave rather like degree achievements and unergative verbs of variable telicity. We claim that these differences must be accounted for in the syntactic representation of locative verbs. While location verbs involve an abstract bounded path, articulated through the combination of a Path preposition and a Place preposition, locatum verbs involve an abstract predicative preposition that allows for degree quantification of the root and contextually determined (a)telicity.
Dynamic mode III interface crack in aluminum matrix composites
Authors: Lü Nianchun , Xiang Qian , Hao Guodong , Wang Yuntao
Published: June 2015

By means of the theory of complex variable functions, dynamic extension queries on symmetrical mode III interface crack in aluminum alloys and aluminum matrix composite materials were studied. The crack extension should also appear in the format of self-similarity because interface failure is ascertained by the maximum tensile stress. The formulation involves the development of a Riemann–Hilbert problem. The queries, considered in this study, can be very readily translated into Riemann–Hilbert problem by ways of self-similar functions. The general representations of analytical solutions of stresses, displacements and dynamic stress intensity factors, for the edges of symmetrical mode III interface crack, subjected to motive enhanced loadings, Px5/t5 and Pt6/x5, respectively, were obtained. In light of the correlative material properties, the changeable law of dynamic stress intensity factor was illustrated very well. After the solutions were utilized by the use of superposition principle, the solutions of discretionally complicated problems were easily acquired.
Taipei et son patrimoine (Taipei and its heritage)
Authors: Böse Margot
Published: June 2015

Résumé. - Taipei, capitale de la République de Chine est située sur l'île de Formose. Cette île dont les habitants indigènes ne sont pas des Chinois a vu croître sa population chinoise depuis le XVIIe siècle. Parallèlement, l'île a connu des tentatives de colonisation par les Hollandais et les Espagnols. Les Chinois ont gouverné Formose dès 1683. La ville de Taipei ne fut fondée qu'en 1875 comme siège préfectoral. Son plan rectangulaire, encore bien visible, a été élargi au cours de l 'urbanisation de tout le bassin dans lequel elle se trouve. Pendant l'époque japonaise (1895-1945), Taipei a été considérablement agrandie. Les bâtiments des institutions éducatives ainsi que les bâtiments gouvernementaux ont toujours marqué de leur empreinte la ville de Taipei. Après la création de la République de Chine en 1949, Chiang Kai Shek avait également choisi cette ville comme capitale. Au cours des deux dernières décennies, Taipei a joué le rôle d'un noyau d'urbanisation rapide pour sa banlieue. Taipei, cette ville moderne, ce centre éducatif et de commerce international, est un mélange intéressant où se côtoient la modernité d'une capitale de puissance économique et les traditions chinoises.
Russie : de la « grande stratégie » à la « guerre limitée »
Authors: Gomart Thomas
Published: June 2015

Au service d’une « grande stratégie », Moscou dispose d’abord de l’arme énergétique : mais l’effondrement des cours du pétrole et le conflit avec l’Ukraine la relativisent fortement. La dimension militaire, traditionnelle, est aujourd’hui limitée à la capacité de mener de « petites guerres » localisées. Reste la volonté d’ériger la Russie en puissance de valeurs contestant la primauté occidentale. Moscou joue ses cartes, mais il s’agit des cartes d’une puissance faible.
Le système Poutine : bâti pour durer ?
Authors: Kastouéva-Jean Tatiana
Published: June 2015

L’annexion de la Crimée et la crise ukrainienne ont permis à Vladimir Poutine d’incarner de nouveau une Russie dominante, autour de valeurs conservatrices rassemblant la nation. Le système politique se crispe en jouant l’opposition vis-à-vis de l’extérieur. L’économie est en crise, mais la population reste encore relativement épargnée. Pour le régime, le danger n’est pas la formation d’une opposition politique, mais l’aggravation de la situation économique, en particulier dans les régions.
Les enjeux du chaos libyen
Authors: Gallet Archibald
Published: June 2015

Clivages géographiques, ethniques, économiques, religieux, dessinent une Libye en plein chaos, disputée par deux gouvernements soutenus par des milices en compétition pour la manne pétrolière. L’installation du djihadisme, le développement de contrebandes multiples, l’exploitation des flux migratoires, sont autant de facteurs qui imposent le désordre libyen comme un enjeu régional décisif. Si les dirigeants politiques libyens semblent s’accommoder de cet état de fait, les États européens sont ici en première ligne.
Défaire Daech : une guerre tant financière que militaire
Authors: Benraad Myriam
Published: June 2015

L’État islamique dispose de revenus importants tirés notamment de sa prise de contrôle de banques, de sa maîtrise des réseaux de contrebande, en particulier d’hydrocarbures, et de soutiens externes. Cependant, son projet politico-militaire lui coûte cher : il doit payer des milliers de combattants et administrer les territoires qu’il contrôle. Pour s’assurer de nouvelles sources de revenus, il cherche à se lancer dans d’autres conquêtes, au-delà de l’Irak et de la Syrie.
Soudan du Sud : de l’État en faillite à l’État chaotique
Authors: Lagrange Marc-André
Published: June 2015

Le Soudan du Sud n’est encore ni un État ni une nation. Déchiré par les rivalités ethniques, divisé entre conceptions diverses de l’organisation de l’État, il ne connaît que la guerre comme moyen de dialogue politique. La gestion de la question pétrolière par les actuels dirigeants a été catastrophique, conduisant le pays à une quasi banqueroute, et touchant gravement le Soudan lui-même. Le Soudan du Sud devient ainsi un élément préoccupant de déstabilisation pour toute la région.
Terrorisme et contre-radicalisation : le modèle danois
Authors: Andersen Lars Erslev
Published: June 2015

Le terrorisme n’a frappé que deux fois au Danemark au cours des 30 dernières années : en 1985 et en 2015. D’autres attaques ont été déjouées, notamment contre les dessinateurs ayant publié des caricatures du prophète Mahomet dans le Jyllands-Posten . Pour faire face au terrorisme, le Danemark a été à l’avant-garde du développement de programmes de contre-radicalisation. Il n’est toutefois pas certain que ces programmes soient efficaces. Ils pourraient même être contre-productifs.