bluuebunny/crossref_metadata_2025 huggingface dataset:
MRI-guided cryoablation for metastatic spine disease: intermediate-term clinical outcomes in 14 consecutive patients
Authors: Moses Ziev B. , Lee Thomas C. , Huang Kevin T. , Guenette Jeffrey P. , Chi John H.
Published: January 2020

OBJECTIVE

Minimal access ablative techniques have emerged as a less invasive option for spinal metastatic disease reduction and separation from neural tissue. Compared with heat-based ablation modalities, percutaneous image-guided cryoablation allows for more distinct visualization of treatment margins. The authors report on a series of patients undergoing MRI-guided cryoablation as a feasible method for treating spinal metastatic disease.

METHODS

A total of 14 patients with metastatic spine disease undergoing MR-monitored cryoablation were prospectively enrolled. Procedures were performed in an advanced imaging operating suite with the use of both CT and MRI to gain access to the spinal canal and monitor real-time cryoablation.

RESULTS

The average age was 54.5 years (range 35–81 years). The mean preoperative Karnofsky Performance Status score was 79.3 (range 35–90). The average radiographic follow-up was 7.1 months (range 25–772 days), and the average clinical follow-up was 9.8 months (range 7–943 days). In 10 patients with epidural disease, 7 patients underwent postprocedural imaging, and of these 71% (5/7) had stable or reduced radiographic disease burden. Bone regrowth was observed in 63% (5/8) of patients with bone ablation during the treatment who had postoperative imaging. Pre- and postoperative visual analog scale scores were obtained, and a significant reduction in these scores was found following ablation. There were no complications.

CONCLUSIONS

MR-guided cryoablation is a minimally invasive treatment option for metastatic spine disease. In patients with epidural disease, the majority experienced tumor reduction or arrest at follow-up. In addition, pain was significantly improved following ablation. The average hospital stay was short, and the procedure was safe in a range of patients who are otherwise not ideal candidates for standard treatment.
FAKTOR MANUSIA DAN FAKTOR PEKERJAAN YANG BERHUBUNGAN DENGAN KECELAKAAN KERJA PT XY TAHUN 2016
Authors: Herdianti  , Hamdani
Published: January 2020

Kecelakaan kerja merupakan suatu rentetan kejadian atau suatu kecelakaan kerja yang terjadi karena akibat dari pekerja pada waktu melaksanakan pekerjaan dan juga disebabkan oleh adanya faktor-faktor atau potensi bahaya yang satu sama lain saling berkaitan. Desain penelitian menggunakan metode cross sectional dan jenis penelitian ini adalah penelitian kuantitatif. Populasi dalam penelitian ini adalah seluruh pekerja yang bekerja di bagian produksi di PT XY kabupaten bungo. Pengambilan sampel dilakukan dengan teknik proportional random sampling dan didapat jumlah sample sebanyak 58 responden. Proses pengumpulan data dilakukan dengan cara membagikan kuesioner kepada responden.Untuk menguji ada tidaknya keterkaitan umur, masa kerja dan unit kerja dengan kecelakaan kerja , peneliti menggunakan uji Chi-Square dengan P-value sebesar < 0,05 . Hasil penelitian antara variabel umur pekerja dengan kecelakaan kerja nmenunjukan P-value sebesar (0,000 < 0,05) yang menunjukkan adanya hubungan , variabel masa kerja dengan kecelakaan kerja menunjukkan P-value sebesar (0,000<0,05) yang menunjukkan adanya hubungan, dan variabel unit kerja dengan kecelakaan kerja menunjukkan adanya P-value sebesar (0,004 < 0,05) yang menunjukkan adanya hubungan dengan kecelakaan kerja. Mengadakan pelatihan untuk menambah wawasan dan skill bagi tenaga kerja serta pengawasan yang lebih intensif agar dapat meminimalisir dan menekan angka kecelakaan kerja
HUBUNGAN PENGALAMAN KERJA DAN ASUPAN KALORI DENGAN PRODUKTIVITAS KERJA PADA PEKERJA MEUBEL DI KABUPATEN MAJENE
Authors: Maarifah Dahlan  , Samsir
Published: January 2020

Produktivitas merupakan fungsi perkalian dari usaha yang didukung dengan motivasi yang tinggi dengan kemampuan yang di peroleh melalui proses latihan. Banyaknya permintaan dan harus diselesaikan dalam batas waktu tertentu menuntut pekerja meubel yang ada di Kabupaten Majene untuk tetap bisa mempertahankan produktivitas kerja. Rumusan masalah yaitu Hubungan pengalaman kerja dan asupan kalori dengan produktivitas kerja pada pekerja meubel di Kabupaten Majene. Tujuan penelitian untuk mengetahui hubungan pengalaman kerja dan asupan kalori terhadap produktivitas kerja pada pekerja meubel di Kabupaten Majene. Penelitian ini merupakan survey analitik dengan menggunakan metode pendekatan studi Cross Sectional. Populasi pada penelitian ini adalah pekerja meubel yang ada di Kabupaten majene. Sampel dalam penelitian ini sebanyak 31 responden dengan menggunakan Cluster Sampling. Tekhnik analisis data menggunakan uji kolmogorov-smirnov untuk mengetahui hubungan pengalaman kerja dan asupan kalori terhadap produktivitas kerja pada pekerja meubel di Kabupaten Majene.Berdasarkan hasil penelitian menunjukkan bahwa ada hubungan asupan kaloriterhadap produktivitas nilai p= 0,020< α= 0,05. Ada hubungan asupan kaloriterhadap produktivitas kerja meubel di nilaip=0,007< α= 0,05. Sehingga dapat disimpulkan bahwa ada hubungan Asupan Kalori terhadap Produktivitas kerja pada pekerja meubel dan juga ada hubungan pengalaman kerja terhadap produktivitas kerja pada pekerja Meubel di Kabupaten Majene p<α. Disarankan kepada pemilik usaha industri meubel untuk memperhatikan menu makanan yang bervariasi dengan porsi makan yang sesuai dengan beban kerja dan bahwa pengalaman kerja merupakan salah satu komponen yang sangat penting agar produktivitas kerja bisa meningkat
ANALISIS PENERAPAN ETIKA DAN HUKUM KESEHATAN PADA PEMBERIAN PELAYANAN KESEHATAN DI RUMAH SAKIT NENE MALLOMO KABUPATEN SIDENRENG RAPPANG
Authors: Anggie Septie Aningrum AN Anggie Septie Aningrum AN
Published: January 2020

Dalam pelayanan kesehatan perilaku petugas kesehatan harus tunduk pada etika profesi (kode etik profesi) dan juga tunduk pada ketentun hukum, aturan, dan perundang-undangan.. Penelitian ini merumuskan masalah yaitu bagaimana pelayanan kesehatan di Rumah Sakit Nene Mallomo Kab.Sidrap, bagaimana penerapan etika dalam pemberian pelayanan kesehatan di Rumah Sakit Nene Mallomo Kab.Sidrap, dan bagaimana penerapan hukum kesehatan dalam pemberian pelayanan kesehatan di Rumah Sakit Nene Mallomo Kab.Sidrap. tujuan dari penelitian ini adalah untuk mengetahui pelayanan kesehatan di Rumah Sakit Nene Mallomo Kab.Sidrap,  penerapan etika dalam pemberian pelayanan kesehatan di Rumah Sakit Nene Mallomo Kab.Sidrap, dan mengetahui penerapan hukum kesehatan dalam pemberian pelayanan kesehatan di Rumah Sakit Nene Mallomo Kab.Sidrap.

Penelitian ini dengan metode survei deskriptif yang dilakukan di Rumah Sakit Nene Mallomo Kab. Sidrap menggunakan kuesioner yang diberikan ke sampel yaitu 99 pasien rawat inap yang ditentukan dengan teknik Accidental Sampling. Data diolah dengan bantuan aplikasi SPSS 24 dan di analisis secara univariate sehingga menghasilkan frekuensi distribusi setiap variabel.

Berdasarkan analisis data didapatkan bahwa Pelayanan kesehatan yang diberikan di Rumah Sakit Nene Mallomo Kab.Sidrap dalam kategori memuaskan  pasien, penerapan etika dalam pemberian pelayanan kesehatan sudah baik dan sesuai dengan aturan kode etika dan, Penerapan hukum kesehatan dalam pemberian pelayanan di Rumah Sakit Nene Mallomo Kab. Sidrap sudah baik dan sesuai dengan aturan perundang-undangan yang berlaku.
PENGARUH PEMBERIAN AIR KELAPA MUDA TERHADAP PENURUNAN TEKANAN DARAH PADA PENDERITA HIPERTENSI DI WILAYAH KERJA PUSKESMAS LANRISANG KABUPATEN PINRANG
Authors: Fandi Andika1 Fandi Andika , Haniarti  , Amir Patintingan
Published: January 2020

Penyakit hipertensi dapat dikendalikan dengan pengobatan non farmalokogis salah satunya air kelapa muda,  karena  kandungan kalium yang terdapat dalam air kelapa muda  sangat bermanfaat untuk menurunkan tekanan darah sistolik dan diastolik. Tujuan penelitian adalah untuk mengetahui pengaruh pemberian air kelapa muda terhadap penurunan tekanan darah pada penderita hipertensi di Wilayah Kerja Puskesmas Lanrisang Kabupaten Pinrang.Jenis penelitian yang digunakan adalah eksprimen kuasi (quasi ekspriment).  Dengan rancangan one group pre test – post test. Variabel independen adalah pemberian air kelapa muda dan variabel dependen adalah penurunan tekanan darah pada penderita hipertensi. Sampelnya sebanyak 52 responden dan teknik sampling yang digunakan adalah accidental sampling. Penelitian ini dilakukan di Wilayah Kerja Puskesmas Lanrisang Kabupaten Pinrang pada Tanggal 25 Maret sampai 30 Juli 2018. Hasil penelitian  ini dapat disimpukan bahwa  ada pengaruh pemberian air kelapa muda terhadap penurunan tekanan darah pada penderita hipertensi di Wilayah Kerja Puskesmas Lanrisang Kabupaten Pinrang.
PENGARUH SISTEM ANTRIAN DAN PELAYANAN DALAM MENINGKATKAN EFEKTTIFITAS PELAYANAN PASIEN RAWAT JALAN DI PUSKESMAS MADISING NA MARIO KOTA PAREPARE
Authors: Santi Milanda  , Usman  , Darmawan Ukkas
Published: January 2020

Loket pendaftaran pasien menjadi ujung tombak pelayanan rawat jalan karena merupakan pelayanan pertama dan secara langsung berinteraksi dengan pasien, sehingga dapat memberikan kesan kepada pasien terhadap mutu pelayanan secara umum. pelayanan yang diberikan di loket pendaftaran  belum optimal, maka menimbulkan waktu tunggu yang lama kepada pasien, kondisi ini dapat memicu rendahnya kepuasan  pasien.  Pada masalah ini, aspek cepat dan tepat sangat diperhitungkan dalam penyelenggaraan jasa pelayanan, artinya membiarkan konsumen menunggu tanpa alasan yang jelas akan menyebabkan persepsi yang negatif dalam mutu atau kualitas pelayanan. Rendahnya mutu pelayanan pada suatu puskesmas akan berkaitan dengan citra puskesmas sekaligus penentu terhadap pemanfaatan ulang pelayanannya. Tujuan penelitian adalah untuk mengetahui sistem antrian dan pelayanan dalam meningkatkan efektifitas pelayanan  pasien rawat jalan. Metode yang digunakan penelitian survey analitik dengan pendekatan cross sectional study. Teknik pengambilan Accidental Random Sampling dengan jumlah sampel 100 orang yang berobat ke Puskesmas Madising Na Mario Kota Parepare. Hasil penelitian berdasarkan hasil uji statistic dengan menggunakan chi square, maka diperoleh p (value) = 0,03 untuk sistem antrian dan untuk pelayanan diperoleh p (value) = 0,04. Kesimpulan penelitian adalah ada pengaruh sistem antrian dan pelayanan dalam meningkatkan efektifitas pelayanan pasien rawat  jalan di Puskesmas Madising Na Mario Kota Parepare
HUBUNGAN DUKUNGAN SOSIAL DENGAN KUALITAS HIDUP ORANG DENGAN HIV/AIDS (ODHA) DI RUMAH SAKIT UMUM LASINRANG KABUPATEN PINRANG
Authors: Rasni Jumliarni  , Usman  , Henni Kumaladewi Hengky
Published: January 2020

HHIV/AIDS saat ini bukan hanya berupa penyakit menular saja, tetapi menjadi masalah kesehatan masyarakat yang sangat luas. Berdasarkan data dari Dinas Kesehatan Kabupaten Pinrang mengenai jumlah kasus HIV/AIDS dari tahun 2013 sampai dengan 2017 sebanyak 50 kasus. Sedangkan data dari Rumah Sakit Umum Lasinrang Kabupaten Pinrang, diketahui bahwa 22 orang yang rutin mengambil ARV.HIV tidak hanya berdampak pada kesehatan fisik tetapi juga berdampak pada psikologis ODHA karena adanya diskriminasi di masyarakat. Dengan kondisi seperti ini, maka perlunya menciptakan lingkungan yang kondusif yaitu dengan cara meningkatkan dukungan sosial bagi ODHA. Tujuan penelitian ini untuk mengetahui hubungan dukungan keluarga, teman dan petugas kesehatan dengan kualitas hidup Orang dengan HIV/AIDS (ODHA) di Rumah Sakit Umum Lasinrang Kabupaten Pinrang. Metode yang digunakan dalam penelitian ini adalah metode deskriptif korelasi dengan rancangan penelitian Cross Sectional Study.Peneliti mengidentifikasi melalui observasional dengan menggunakan kuesioner pada sampel, dimana sampel dalam penelitian ini sebanyak 22 orang. Data dianalisis secara univariat dan bivariat  menggunakan uji statistik Chi Square  melalui SPSS Versi 24. Hasil penelitian menunjukkan bahwa ada hubungan dukungan keluarga (p = 0,010), tidak ada hubungan dukungan teman (p = 0,115), dan ada hubungan dukungan petugas kesehatan (p = 0,046) dengan kualitas hidup Orang dengan HIV/AIDS (ODHA) di Rumah Sakit Umum Lasinrang Kabupaten Pinrang. Penelitian ini menyarankan agar teman ODHA meningkatkan pemahaman dan pengetahuan mengenai HIV/AIDS serta lebih menghargai status ODHA
HUBUNGAN STATUS GIZI DENGAN KUALITAS HIDUP LANSIA DI WILAYAH PUSKESMAS MADISING NA MARIO KOTA PAREPARE
Authors: Indah Pratiwi  , Haniarti  , Herlina Muin
Published: January 2020

Status gizi dikatakan baik bila pola makan kita seimbang. Artinya, asupan, frekuensi dan jenis makanan yang dikomsumsi harus sesuai dengan kebutuhan tubuh. Menurut World Health Organization Quality of Life (WHOQOL), Kualitas Hidup adalah kondisi fungsional lansia yang meliputi Kesehatan fisik, kesehatan psikologis, hubungan sosial, dan hubungan lingkungan.Tujuan penelitian ini untuk menunjukkan adakah hubungan status gizi dengan kualitas hidup lansia di tinjau dari kesehatan fisik, kesehatan psikologis, kondisi sosial, kondisi lingkungan di Wilayah Kerja Puskesmas Madising Na Mario Kota Pare – Pare. Metode yang digunakan dalam penelitian ini adalah metode analitik dengan pendekatan cross sectional study. Peneliti mengidentifikasi melalui obeservasional dengan menggunakan kuesioner pada sampel, dimana sampel dalam penelitian ini sebanyak 89 orang. Data dianalisis secara univariat dan bivariat menggunakan uji chi square melalui SPSS Versi 24.Hasil penelitian menunjukkan bahwa ada hubungan kesehatan fisik (0,009<0,05), tidak ada hubungan kesehatan psikologis (0,450>0,05), ada hubungan kondisi sosial (0,014<0,05), tidak hubungan kondisi lingkungan (0,241>0,05) dengan status gizi lansia di Wilayah Kerja Puskesmas Madising Na Mario Kota Parepare
HUBUNGAN PEKERJAAN DAN KONDISI SOSIAL BUDAYA DENGAN STATUS GIZI MASYARAKAT DI DESA LAWALLU KECAMATAN SOPPENG RIAJA KABUPATEN BARRU
Authors: Nursamsi  , Haniarti  , Abidin
Published: January 2020

Masalah gizi masyarakat di Desa Lawallu Kecamatan Soppeng Riaja Kabupaten Barru, bukan menyangkut aspek kesehatan saja, melainkan aspek kondisi sosial budaya, dan sebagainya. Kasus gizi/status gizi masyarakat akhir-akhir ini di Indonesia telah menyadarkan pemegang kebijakan untuk melihat lebih jelas bahwa orang dewasa sebagian kekurangan gizi. Penyebab kurang gizi, pertama makanan yang kurang dan penyakit infeksi yang di derita masyarakat, ketahanan pangan di keluarga, pola pengasuhan anak, pelayanan kesehatan dan kesehatan lingkungan, dan kondisi sosial budaya.Tujuan penelitian ini adalah untuk mengetahui adakah hubungan pekerjaan dan kondisi sosial budaya dengan status gizi masyarakat. Jenis penelitian survey analitik dengan pendekatan cross sectional study. Populasi dalam penelitian adalah semua masyarakat yang berumur 21-65 tahun yang berjumlah 1190 orang di Desa Lawallu dan sampel 92 orang. Data dianalisis secara univariat dan bivariat menggunakan uji statistic Chi Square melaliu SPSS Versi 24.Hasil penelitian menunjukkan bahwa tidak ada hubungan antara pekerjaaan terhadap status gizi masyarakat di Desa Lawallu Kecamatan Soppeng Riaja Kabupaten Barru berdasarkan hasil Uji Chi Square, yang di peroleh dengan taraf signifikan (0.089) > a (0.05), sedangkan kondisi sosial budaya terhadap status gizi masyarakat di Desa Lawallu Kecamatan Soppeng Riaja Kabupaten Barru di peroleh dengan taraf Signifikan (0.479) > a (0.05), maka H0 di tolak. Disarankan perlunya pendidikan gizi kepada masyarakat sebagai pengolahan menu keluarga untuk meningkatkan status gizi masyarakat.
β-Lactolin, a Whey-Derived Lacto-Tetrapeptide, Prevents Alzheimer’s Disease Pathologies and Cognitive Decline
Authors: Ano Yasuhisa , Ohya Rena , Takaichi Yuta , Washinuma Terukatsu , Uchida Kazuyuki , Takashima Akihiko , Nakayama Hiroyuki
Published: January 2020

The prevention of age-related memory decline and dementia has been becoming a high priority because of the rapid growth in aging populations. Accumulating epidemiological and clinical studies indicate that intake of fermented dairy products rich in β-lactolin improves memory retrieval and executive function and attenuates cognitive decline in the elderly. However, the effects of long-term consumption of β-lactolin on Alzheimer’s disease (AD) pathologies have not been investigated. In the present study, we examined the effects of β-lactolin and whey digestion rich in β-lactolin on AD pathology in 5×FAD transgenic mice and PS19 tauopathy mice. Intake of β-lactolin and whey digestion rich in β-lactolin reduced the levels of inflammatory cytokines, suppressed the infiltration of activated microglia, decreased the levels of amyloid-β, ameliorated impaired long-term object memory, and attenuated decreased synaptophysin, dopamine, brain-derived neurotrophic factor, and insulin-like growth factor 1 levels in the cortex in 5×FAD transgenic mice. In addition, intake of β-lactolin and whey digestion rich in β-lactolin improved behavioral abnormality and reduced the ratio of phosphorylated tau to total tau in the cortex in PS19 tauopathy mice. These findings indicate that consumption with β-lactolin and whey digestion rich in β-lactolin suppresses inflammation and attenuates AD pathology and cognitive impairment.
The Association of Post-Stroke Cognitive Impairment and Gut Microbiota and its Corresponding Metabolites
Authors: Liu Yongqiang , Kong Cheng , Gong Li , Zhang Xiaohui , Zhu Yuefei , Wang Haichao , Qu Xiao , Gao Renyuan , Yin Fang , Liu Xueyuan , Qin Huanlong
Published: January 2020

Background:

Post-stroke cognitive impairment (PSCI) is an important factor causing disabilities after acute ischemic stroke (AIS). Emerging evidence suggested that gut microbiota play an important role in cognitive impairment.

Objective:

This study aimed to explore the association between PSCI and gut microbiota.

Method:

65 patients with newly diagnostic AIS finished the fecal collection on admission and cognitive assessment 3 months later in the clinic. Fecal samples were subjected to 16SrRNA gene sequencing and gas chromatography-mass spectrometry analysis. Additionally, we enrolled new 18 AIS patients, whose treatment was supplemented by probiotics, to assess the potential of microbial treatment in PSCI.

Results:

PSCI patients were characterized by the significantly decreased alpha-diversity, disturbed microbial composition, and corresponding metabolites compared with non-PSCI patients. Increased Fusobacterium and deficiency of microbial metabolized short-chain fatty acids (SCFAs) were significantly associated with PSCI. A model based on gut microbiota and SCFAs could predict 3 months or longer PSCI early and accurately after stroke onset. While traditional probiotic administration had little effect on PSCI, it could ameliorate patients’ mood, including depression and anxiety in the 3 months after stroke.

Conclusion:

Our study revealed the association between PSCI and gut microbiota and its corresponding metabolites for the first time, suggesting the potential for applying microbiota and its corresponding metabolites to early clinical diagnosis and treatment of PSCI.
Chromogranin A Analysis in the Differential Diagnosis Across Lewy Body Disorders
Authors: Gmitterova Karin , Varges Daniela , Schmitz Matthias , Zafar Saima , Maass Fabian , Lingor Paul , Zerr Inga
Published: January 2020

Background:

Chromogranin A (CgA) is a general marker of gut endocrine cells, which are part of the “gut-brain axis” in Parkinson’s disease (PD).

Objective:

We analyzed CgA as a marker of synaptic dysfunction to assess its role in the differential diagnosis across different Lewy body disorders.

Methods:

We analyzed the CgA levels in the cerebrospinal fluid (CSF) and serum from 54 patients covering the spectrum of Lewy body disorders [13 Parkinson’s disease (PD), 17 Parkinson’s disease dementia (PDD), 24 dementia with Lewy bodies (DLB)] and 14 controls using an ELISA.

Results:

A positive correlation was noted between CSF and serum CgA levels ( ρ= 0.47, 95% CI: 0.24 to 0.65, p < 0.0001). The highest values of CgA in CSF and in serum were measured in DLB and there was a significant difference between DLB and PDD ( p = 0.03 and p = 0.004). The serum levels of CgA in controls achieved lower values compared to DLB ( p = 0.006). There was a gradual increase in serum levels from PD to PDD and DLB. An inverse correlation was seen between the CSF level of CgA and Aβ42 ( ρ  = –0.296, 95% CI: –0.51 to –0.04, p = 0.02).

Conclusion:

The incorporation of CgA analysis as an additional biomarker may be useful in the diagnostic work-up of Lewy body dementia. CgA analysis may be relevant in distinguishing DLB from PDD patients and presumably early stages of PD. Our data on altered serum levels in DLB pave the way to the development of blood-based parameters for the differential diagnosis, which however needs to be confirmed in a prospective study.
Directly use conductive materials in tissue engineering applications
Authors: Feng Ke , Wei Wenbo , Yang Chen , Dong Shaozheng
Published: January 2020

Artificial scaffolds play an important role in tissue engineering, which is used to mimic extracellular matrix (ECM) and provide a suitable microenvironment for cell growth. Many natural and synthetic biomaterials have been used to fabricate two dimensional or three dimensional scaffolds. However, missing electrical conductivity of these materials is one of the disadvantages. Recently, conductive polymers (CPs) and conductive nanomaterials (CNMs) have been chosen for doping into scaffolds to improve their conductivity. This review focuses on conductive scaffolds design, fabrication and application in tissue engineering for enhancing cell attachment and proliferation, promoting differentiation and maturation with and without electrical stimulations.
A novel three-market view of price competitiveness
Authors: Felettigh Alberto , Giordano Claire
Published: January 2020

A country’s price competitiveness is generally proxied by the real effective exchange rate of its currency. In this article we present a novel three-market breakdown (domestic, euro-area and non-euro area markets) of this measure, with an application to the four main euro-area countries. Price-competitiveness developments are indeed found to be heterogeneous across markets, thereby confirming the usefulness of this decomposition. In particular, we find that in the 1999–2018 period only Germany recorded comparable (large) gains in both euro and non-euro area markets. France posted a larger gain, and Spain marked a smaller loss, in euro-area markets; conversely, Italy’s mild improvement was greater in non-euro area markets. Finally, competitiveness in the domestic market and that in non-euro area markets are found to be the main, equally important, drivers of overall developments since 1999 in Italy and in Germany.
Ohio medicaid expansion enrollees: Impact of loss of coverage on access to care, 2018
Authors: Nau Michael , Cohen Steven B.
Published: January 2020

This study investigates the extent to which former Medicaid expansion enrollees transition to other forms of health insurance coverage, and whether loss of Medicaid is associated with greater difficulties accessing health care. Findings from a 2018 survey of current and former enrollees in Ohio’s Medicaid expansion program revealed that nearly two-thirds of respondents no longer covered by Medicaid had transitioned to another form of insurance coverage. The most prevalent reason for not having coverage among the remaining one-third was affordability. Former Medicaid enrollees that obtained other sources of coverage also reported greater difficulties accessing health care services than their counterparts remaining on Medicaid. The prevailing explanation as to the cause of experiencing difficulties in accessing health care was the expense. These findings demonstrate that for former Medicaid enrollees, perceived high costs are a significant barrier to obtaining non-Medicaid coverage and accessing health care services.
Violência entre Parceiros Íntimos, Gênero e Saúde: a Integralidade, a Interseccionalidade e a Pedagogia Feminista no Acolhimento às Mulheres e na Educação em/na Saúde
Authors: Dantas-Berger Sônia Maria
Published: January 2020

A partir de breve demarcação e conceituação do problema da violência contra mulheres, sob as perspectivas de gênero, direitos humanos e saúde pública e, da constatação de sua persistente invisibilidade na assistência em saúde, o artigo aponta algumas consequências para a saúde das mulheres, problematiza o modo como profissionais  lidam com tal fenômeno social e, sinaliza limites e demandas abarcados no processo de educação em/na saúde frente ao tema da violência entre parceiros íntimos (VPI), apostando-se na potencialidade do diálogo entre os pressupostos feministas e freirianos para o acolhimento das mulheres em situação de violência, orientado pelos princípios  da integralidade e da interseccionalidade.
Efisiensi Kompor Surya Parabola Berreflektor Cermin Untuk Menunjang Ketahanan Energi
Authors: Subarjo Abdul Haris , Mardwianta Benedictus , Wicaksono Anugrah Budi
Published: January 2020

Radiasi matahari menghasilkan kalor sebagai sumber energi yang dapat dikumpulkan menjadi satu titik sehingga mampu untuk memasak air menggunakan alat bernama Reflektor cermin parabolic. Untuk memperbesar perpindahan kalor menyeluruh (Qm) maka dipilih bahan reflector yang mudah memantulkan sinar matahari. Tujuan yang dilakukan pada penelitian ini adalah untuk mengetahui daya dan efisiensi termal kolektor pada kompor tenaga surya. Metodologi penelitian ini dengan cara pengambilan data dengan parameter waktu yang sudah ditentukan sesuai kondisi  lingkungan untuk memanaskan air 1000 gram. Subyek penelitian ini adalah parabolic solar cooker dengan diameter 84 cm. Hasil daya kompor yang diperoleh sebesar 36,59 Watt dan efisiensi termal kompor sebesar 6,18 %. Daya kompor dipengaruhi oleh selisih temperatur air setelah dipanaskan dengan temperatur air sebelum dipanaskan. Semakin besar temperatur air setelah dipanaskan maka akan memperbesar daya kompor tersebut. Semakin besar perpindahan kalor menyeluruh Qm dan semakin kecil intensitas radiasi matahari pada reflector yang menggunakan cermin maka efisiensi termal semakin besar.Kata kunci: kompor parabola tenaga surya, daya kompor, efisiensi termalABSTRACTSolar radiation generates the heat as a source of energy that can be collected into a single point so that it is able to cook water using a tool named mirror parabolic reflector. To enlarge the whole heat transfer (QM) then selected reflector material that easily reflects the sunlight. The purpose of this study is to find out the power and efficiency of thermal collectors on solar power stoves. This research methodology by means of data retrieval with specified time parameters according to environmental conditions to heat water 1000 grams. The subject of this study is the parabolic solar cooker with a diameter of 84 cm. Results of stove Power obtained at 36.59 Watt and thermal efficiency of the stove amounted to 6.18%. The cooker's power is influenced by the water temperature difference after heated with water temperature before heated. The larger the water temperature after heated it will enlarge the stove's power. The larger the overall heat transfer of the Qm and the smaller the intensity of the solar radiation on the reflector using the mirror hence the greater the thermal efficiency.
Non-neutralizing Antibodies Directed at Conservative Influenza Antigens
Authors: Sedova E. S. , Scherbinin D. N. , Lysenko A. A. , Alekseeva S. V. , Artemova E. A. , Shmarov M. M.
Published: January 2020

At the moment, developing new broad-spectrum influenza vaccines which would help avoid annual changes in a vaccines strain set is urgency. In addition, developing new vaccines based on highly conserved influenza virus proteins could allow us to better prepare for potential pandemics and significantly reduce the damage they cause. Evaluation of the humoral response to vaccine administration is a key aspect of the characterization of the effectiveness of influenza vaccines. In the development of new broad-spectrum influenza vaccines, it is important to study the mechanisms of action of various antibodies, including non-neutralizing ones, as well as to be in the possession of methods for quantifying these antibodies after immunization with new vaccines against influenza. In this review, we focused on the mechanisms of anti-influenza action of non-neutralizing antibodies, such as antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), and antibody-mediated complement-dependent cytotoxicity (CDC). The influenza virus antigens that trigger these reactions are hemagglutinin (HA) and neuraminidase (NA), as well as highly conserved antigens, such as M2 (ion channel), M1 (matrix protein), and NP (nucleoprotein). In addition, the mechanisms of action and methods for detecting antibodies to neuraminidase (NA) and to the stem domain of hemagglutinin (HA) of the influenza virus are considered.
DARPins: Promising Scaffolds for Theranostics
Authors: Shilova O. N. , Deyev S. M.
Published: January 2020

Monoclonal antibodies are the classical basis for targeted therapy, but the development of alternative binding proteins has made it possible to use non-immunoglobulin proteins as targeting modules. The advantages of DARPins, scaffold proteins based on ankyrin repeats, over antibodies are as follows: small size, stability over a wide range of temperatures and pH values, low aggregation tendency, and ease of production in heterologous expression systems. The differences in the structure of the paratope of DARPin and antibodies broaden the spectrum of target molecules, while the ease of creating hybrid fusion proteins allows one to obtain bispecific and multivalent constructs. In this article, we summarize recent data on the development of therapeutic and imaging compounds based on DARPins.
The Role of Heritable Tumors in Evolution of Development: a New Theory of Carcino-evo-devo
Authors: Kozlov A P
Published: January 2020

The hypothesis of evolution by tumor neofunctionalization (the main hypothesis) describes the possible role of hereditary tumors in evolution. The present article examines the relationship of the main hypothesis to other biological theories. As shown in this paper, the main hypothesis does not contradict to the existing biological theories, but fills the lacunas between them and explains some unexplained (or not completely understood) questions. Common features of embryonic development and tumorigenesis are described by several recognized theories. Similarities between normal development and tumorigenesis suggest that tumors could participate in the evolution of ontogenesis and in the origin of new cell types, tissues and organs. A wide spectrum of non-trivial explanations and non-trivial predictions in different fields of biology, suggested by the main hypothesis, is an indication of its fundamental nature and the potential to become a new biological theory, a theory of the role of tumors in evolution of development, or carcino-evo-devo.
Tear Fluid Catecholamines As Biomarkers of the Parkinson’s Disease: A Clinical and Experimental Study
Authors: Kim A. R. , Nodel M. R. , Pavlenko T. A. , Chesnokova N. B. , Yakhno N. N. , Ugrumov M. V.
Published: January 2020

An important approach to an early diagnosis of Parkinsons disease (PD) is screening for peripheral biomarkers in patients at the early clinical stage. In this study, we evaluated catecholamine concentration changes in the tear fluid of untreated PD patients as biomarkers. Norepinephrine and dopamine concentrations in the tear fluid of patients were found to increase compared to those in age controls, which was especially pronounced on the side where motor symptoms appeared. On the contrary, the epinephrine concentration in the tear fluid of patients was reduced bilaterally. Since there was no reason to consider the markers found in the clinical stage of PD as markers of the preclinical stage, we additionally studied the tear fluid composition in mouse neurotoxic models of PD preclinical and clinical stages. The norepinephrine concentration in the tear fluid of mice from the clinical stage model was found to be higher than that in controls; in the preclinical stage model, the norepinephrine concentration had a tendency to increase. Therefore, both PD patients and mice from PD preclinical and clinical stage models manifest unidirectional changes in their tear fluid compositions, which may be considered as promising biomarkers for the development of early diagnosis.
基于Mugeda平台课程在职业院校中的教学探索与实践
Authors: 袁 博
Published: January 2020

互联网的飞速发展促进了新媒体营销的腾飞,HTML5的作品已经成为社交媒体时代的营销代表。随着HTML5在互联网的普及,交互设计师逐渐成为稀缺人才。我院开设的Mugeda平台课程主要针对Mugeda平台进行系统学习,Mugeda平台是一个专业级HTML5交互动画制作云平台。本文主要围绕Mugeda平台课程在职业院校中的教学做出研究和讨论。
民办高校班级日常事务精细化管理
Authors: 梁 瑞娜 , 赵 效鹏
Published: January 2020

民办高校班级的日常事务管理需要高度重视,因为不仅关系到学生在校的学习环境和生活,而且影响着学生的未来发展。目前,民办高校在班级日常事务管理上仍然存在诸多问题,比如忽视班级日常事务管理、管理不够全面等,导致了班级日常事务管理的效率与学校的发展进度相脱节。为提高民办高校班级日常事务的精细化管理,本文针对其进行深入探究并提出相应的解决措施。
民族乐器促进国学传播的研究
Authors: 杨 浩 , 周 博 , 王 春龙
Published: January 2020

民族乐器作为当代社会小众群体喜爱的艺术形式,与中国艺术文化的历史息息相关。中国对民族乐器艺术非常重视,并且将民族乐器纳入中国传统文化保护中,这使民族乐器艺术迎来了另一个春天。民族乐曲的曲目创作者们更是深入大众基层生活之中,体验生活、享受生活、为人民服务,并把真正的民族乐器艺术根植在人民当中。中国有着五千年的文明历史,各种文化遗产层出不穷,国学作为多元文化遗产之一尤为重要。在信息化时代发展的今天,国学文化的传播与发展具有着十分重要的战略意义。
高职院校大学生思想政治教育调查结果及归因
Authors: 徐 梦潇 , 刘 新春
Published: January 2020

大学生思想政治教育是我国高校教育中极为重要的内容,但随着全球化的加深和信息技术的不断发展,当代大学生的思想也不断受到影响。通过对湖南2所高职院校调研发现,当前高职院校学生对于思政课的参与度不高,并且欠缺主动学习的积极性,从而制约了思想政治教育课教学的有效性。本文以问卷的形式通过对学生的到课率、课内课后思考情况以及学生对于教师教学反馈等调研内容数据汇总,揭示了当前高职院校学生思想政治教育的现状,并分析了其原因。
Características produtivas de cultivares de cebola no submédio do Vale do São Francisco
Authors: Yuri Jony Eishi , Costa Nivaldo Duarte , Resende Geraldo Milanez de
Published: January 2020

O uso de cultivar adaptada às condições locais é um dos principais fatores que contribuem para o maior rendimento da cebola. Com o objetivo de avaliar a produtividade de cultivares de cebola mais adaptados e produtivas, e que atendam o mercado consumidor nacional nas condições do Submédio do Vale do São Francisco, foi conduzido um experimento no período de julho a novembro de 2016. Usou-se o delineamento experimental de blocos ao acaso, com 20 cultivares e quatro repetições. A produtividade total de bulbos variou de 37,6 a 89,7 t ha-1. As cultivares Luana (89,2 t ha-1), Luana 1205 (85,6 t ha-1), Atacama (83,2 t ha-1), Fernanda (83,1 t ha-1) e Serena (82,5 t ha-1) foram as mais produtivas comercialmente, sem evidenciar diferenças significativas entre si. A massa fresca do bulbo variou entre 92 e 159 g bulbo-1. As cultivares Serena, Atacama, Luana, Fernanda e Mata Hari apresentaram os melhores resultados em termos de classificação de bulbos comerciais, com a maioria dos bulbos classificada nas classes 3, 4 e 5. Pelos resultados, em função das diferentes características avaliadas, as cultivares Luana, Luana 1205, Atacama, Fernanda e Serena foram as mais adaptadas e com maior produtividade, para as condições de cultivo no Submédio do Vale do São Francisco.
PENGARUH REGULASI DAN KOLABORASI TERHADAP LITERASI KEUANGAN DALAM UPAYA PENERAPAN FINANCIAL TECHNOLOGY PADA USAHA KECIL DAN MENENGAH
Authors: Herdinata Christian , Kohardinata Cliff
Published: January 2020

Financial Technology (Fintech) telah memberikan akses kepada banyak pihak yang tidak memiliki rekening bank untuk masuk ke sektor usaha formal. Penerapan Fintech terbukti mampu membuka akses yang lebih besar terhadap layanan jasa keuangan formal, mendorong pertumbuhan ekonomi, serta pembangunan inklusif dan berkelanjutan. Untuk mendukung penerapan Fintech di Indonesia, maka tujuan penelitian ini adalah mengetahui pengaruh regulasi dan kolaborasi terhadap literasi keuangan pada usaha kecil dan menengah di Jawa Timur - Indonesia. Penelitian ini dilakukan melalui pendekatan kuantitatif dengan menggunakan teknik analisis regresi berganda. Hasil dari penelitian ini yaitu regulasi dan kolaborasi berpengaruh signifikan terhadap literasi keuangan. Maka dari itu, penelitian ini dapat membantu banyak pihak yaitu pemerintah, pengusaha, dan konsumen dalam memberikan pemahaman secara lengkap dan menyeluruh berkaitan dengan literasi keuangan pada usaha kecil dan menengah berkaitan penerapan financial technology.
EFFECT OF WORK STRESS, WORK MOTIVATION, AND WORK ENVIRONMENT TO EMPLOYEE PERFORMANCE PRODUCTION PART
Authors: Kristanti Desi , Pangastuti Ria Lestari
Published: January 2020

This research was conducted to test work stress, work motivation, work environment on employee performance. The research sample was 50 respondents and used a total sampling method. This study uses a quantitative approach, data for this study were obtained through a research questionnaire that was filled out by predetermined respondents. Variables are measured with a Likert scale. Hypothesis testing using SPSS V20 tools with multiple linear regression analysis methods.The findings about the effect of work stress, work motivation, work environment on the performance of employees of UD. Patama Karya city of Kedirir. First, work stress and work motivation have no significant impact on employee performance. Second, the work environment has a significant effect on employee performance. Third, the work stress silmultually variable work motivation and work environment significantly influence employee performance.

The results of this study are expected to be the basis for developing new strategies in an effort to improve work stress, work motivation, work environment on employee performance.
Strategi Pemilihan Proyek Pembangunan Pembangkit Listrik dengan Metode Analytical Hierarchy Process (AHP) di PT Pembangkitan Jawa Bali (PT PJB)
Authors: Pratomo Heru Budi , Tjahjadi Bambang
Published: January 2020

The government launched a 35,000 MW program based on the Decree of the Minister of Energy and Mineral Resources of the Republic of Indonesia especially for outside Java region as part of development of country infrastructure. To be able to continue to grow and compete, PT PJB as a company engaged in the field of electric power producers must have good investment plan, one of the investments that can be made is through participation in electric power plant development projects. The purpose of this study is to find out the influential criteria in making decisions and provide recommendations to PT PJB in the formulation of alternative priority scales for power plant development projects selection strategy. This study uses a qualitative approach with a case study approach. Samples from this study were key informants using purposive sampling and filling out questionnaires. The results of this study are the formation of 3 criteria which are the best priorities, namely generating new revenue with a weight of 0.177, market share with a weight of 0.134 and increasing opportunities in the future with a weight of 0.127. While the determination of the main alternative for the construction of the Power Plant Project is the Java 7 PLTU of 16.3%, the Java 8 PLTU of 12.9% and the Java 3 PLTGU of 10%.
Bentuk Kekerasan Pada Sinetron Anak Langit
Authors: Berthniastuti Matau Jubaidah , Ghofur M. Abdul
Published: January 2020

Anak Langit soap opera is a soap opera broadcast by sctv stations produced by sinemart. The program is very popular with the audience, especially among teenagers who are still sitting on the school bench. This soap opera shows many events that are not educational to the audience such as scenes of violent acts in the form of brawls, reckless wild races on the highway and scenes of love outside the boundaries as school children. The focus of the problem that will be examined is the meaning of icons, indexes and symbols, and also forms of violence in the soap opera shows. In this study using qualitative research methods by collecting data through observation, interviews and documentation.The results of this study can be concluded that every scene that is in the soap opera child sky has a meaning that affects the assumptions for the community because not only adults who watch this program, but also many children who watch the show moreover this soap opera airing on primetime. These things tarnished the meaning of love in the soap opera anak langit.
Implementasi Kinerja Bagian Humas dalam Menyebarluaskan Informasi Tentang Program Spirit 99 Hari Kerja Walikota Malang
Authors: Aris Arlinda Silvi , Prasetya Widodo Herru
Published: January 2020

This study aimed to find out how the implementation of the Public Relations Officers in disseminating information about the Spirit 99 Days Work Program from the city Mayor of Malang, and to find out what obstacles occured in the implemention. This study used a qualitative method and the determination of respondents used a snowball sampling. The data collection techniques were through interviews, observation, documentation and the data analysis techniques included reduction, presentation, and verification. From the results of the study showed that the implementation of the public relations performance department in disseminating information, seen from the organization was effective and efficient. In the preparation of the public relations department did two approaches, namely based on the quantity and quality of its human resources, but in a communication policy Public Relations Section has not yet applied the basic tasks of government public relations. Directing the Public Relations Section was through formal and informal forms. While the supervision was through the IMM (Intelligence Media Management) software system which can monitor, collect online, printed and TV media content. From the assessment, the public relations department got some big problems with the existence of Spirit 99Work Days programs that have not been implemented. The inhibiting factors were inadequate funding and human resources and also the ineffective communication.
Pesan Moral Dalam Film Yowis Ben
Authors: Andy Wicaksono Galuh , Qorib Fathul
Published: January 2020

The number of movies made in Indonesia there are several films that give a good moral message in it. Through the movie "Yowis Ben" the director tried to make something new and different from the comedy genre films on previous comedy films. The purpose of this research is to know and understand the moral messages contained in the movie Yowis Ben. In this study used qualitative research method by using the research object of the Film Yowes Ben. While the data analysis technique uses the semiotic analysis of Charles Sander Pierce which is based on logic, with reasoning through the signs. The Model that shows the three main elements of the marking forming is representament, object and Interpretant. The results of this research show that the YOWIS BEN film has a moral message in various sides of life through signs that are munncul both visual and verbal in their respective stories. There is a moral message related to Bayu's life. It can therefore be concluded that the figures and the talks that exist in each scene are a representation of the moral message.
Memperkokoh Posisi Tawar Politik Pegiat Sistem Penyediaan Air Minum Berbasis Masyarakat Lewat Komunikasi Lingkungan
Authors: Effendy Rochmad , Amin Rofikul , Indra Kusuma Ginanjar
Published: January 2020

The limited ability in providing a good water services to all citizens, as well as the fact that water is a public good, the involvement of citizens in drinking water supply is one way to achieve this goal. The existence of a community-based drinking water supply system in the form of the Community Drinking Water User Association (HIPPAM) needs to be maintained to ensure the sustainability of its social services. The sustainability of the HIPPAM social enterprise is determined by internal aspects such as governance and institutional performance, financial management, technical performance of water distribution services. Other things related to external aspects such as the support of stakeholders such as customers, community members, environment activist and village government related to the issue of conservation as well as environmental sustainability and good water governance. Discussing these issues with all stakeholders in drinking water in the available local public space can be referred to as environmental communication that is hoped will be able to create awareness and citizen’s collective action citizens on the importance of good water governance. This study uses qualitative data with interviews and in-depth interviews as data collection techniques, the informants of this study consisted of the management of the HIPPAM Mangga Dua. The result showed that administrators had sufficient environmental and ecological literacy. For them, water is spiritual and social energy sources that enable them to develop dan enhance the community’s social capital.
Pola Komunikasi Keluarga Antara Menantu dan Mertua yang Tinggal dalam Satu Rumah
Authors: Saro Elisabeth , Ghofur M. Abdul , Rakhim Syahida Amanah
Published: January 2020

The study used qualitative research methods. The research is intended to know and understand in more detail related to the phenomenon of what is experienced by the subject to be investigated, through various data collection techniques conducted by researchers to obtain data on "Family Communication Patterns between Daughter-in-law and In-laws who live in one house in Bendrong Village Jabung District”. The problem is analyzed using the Rogers and Kincaid paradigms. The research method used was descriptive qualitative and the sampling technique used was puposive sampling by interviewing 6 informants in Bendrong village. Data collection taken using interview guides, observations and documentation. While data analysis is collecting data, reducing data, presenting data and drawing and conclusions. The results of the study revealed that where the pattern of communication between in-laws and in-laws often exchanges information, as shown in the chart above, where in-laws are usually the speakers or can be referred to as communicators, while the sons-in-law as recipients of messages or communicants, but usually often exchange positions within the period specific time and situation. Messages or information conveyed both by in-laws and in-laws are usually spoken directly or face to face or indirectly such as through social media mobile phones. In this case there is a reciprocal relationship between the two. Thus, the relationship between the daughter-in-law and the mother-in-law who tends to conflict will get worse if the two of them live together, because the high intensity of confusion results in a higher chance of friction.
Practice and Discussion on Lighting Design of Urban Landscape Bridge
Authors: ZHANG Wenting , WANG Jianjun
Published: January 2020

The design status of an urban landscape bridge lighting system was analyzed via system analysis. Through the evaluation of eight twolevel, 24 three­level, and five four­grade indexes on the basis of three aspects, namely, design process, electricity consumption calculation, and lighting effect. The hierarchy framework and index relationship of the entire system were clearly defined. Many angles reflected the links involved in the design of bridge lighting system. The neural network method was used in verifying the screening results to provide a comprehensive indicator specimen for establishing the evaluation system of the system. On the basis of the knowledge and experience of experts, information was processed, and the subjective influence and uncertainty of human calculation could then be reduced.
Cari Açığın Finansmanı: Türkiye için Bir Model Önerisi
Authors: KUZU Mehmet
Published: January 2020

2000’li yılların başından bu yana
gelişmekte olan piyasa ekonomileri düşük kur-yüksek faiz politika çerçevesi ve
cari açığa dayalı büyüme politikası uygulamışlardır. Bunun sonucu olarak bu
ekonomiler yüksek cari açık vermişlerdir. Yüksek cari açık ve bunun finanse
edilememesi döviz kuru riskinin arttığı dönemlerde kur, enflasyon ve faiz
arasındaki etkileşimlerdeki dengelenmeyi bozarak ekonominin ısınmasına neden
olmuştur. Bu çalışmanın amacı; cari işlemler dengesini ve cari açık sorununu
teorik olarak analiz edip Türkiye için cari açık sorununun çözümü için bir
program ve politika çerçevesi içeren model önerisi yapmaktır. Önerilen program
rekabetçi ve istikrarlı ekonomiye geçiş programı olarak adlandırılmış programın
içeriğinde yer alan politika çerçevesi düşük enflasyon yüksek finansal istikrar
politika çerçevesi olarak isimlendirilmiştir.