bluuebunny/crossref_metadata_2025 huggingface dataset:
Mental Health Experiences With COVID-19 Public Health Measures in an Alberta First Nations Community
Authors: Lee Cerina , Wozniak Lisa A , Soprovich Allison L , Sharma Vishal , Healy Bonnie , Samanani Salim , Eurich Dean T
Published: September 2021

Background: The First Nations (FN) peoples of Canada have experienced health inequalities intergenerationally and life course due to colonization, significant social, physical and economic challenges. Consequently, the COVID-19 pandemic has resulted in an exacerbation of health inequities and mental health issues for FN communities around the world. This study aims to understand their experiences related to mental health in an Alberta FN community during the early stages of the pandemic. Methods: In partnership with FN leadership, the study implemented an online cross-sectional survey. Adults from a large FN community in Alberta, Canada, were asked to complete a survey, including two mental health-related screening questionnaires: 1) Generalized Anxiety Disorder-2 item; and 2) Patient Health Questionnaire-2 item. In addition, respondents could provide responses to open-ended questions about their experiences. Results: Among 106 respondents, 95 (89.6%) finished the survey; 18% of adults screened positive for depressive symptoms (score of 3 or greater) and reported difficulty following public health advice for using hand sanitizer, maintaining social distancing, or self-isolating. 21% of adults screened positive for symptoms of anxiety (score of 3 or greater) and reported difficulty maintaining social distance, self-isolating, obtaining food and clothing, or meeting other basic living requirements. Conclusions: FN communities may be disproportionately affected by COVID-19, and may experience exacerbated symptoms of anxiety, depression and overall poor mental health and well-being in response to public health advice. Additional supports and services, including for mental health, should be considered for FN in the context of COVID-19 public health measures.
Based on network pharmacology, using methods such as molecular docking and gene difference analysis, small molecule compounds for the treatment of lung adenocarcinoma and lung squamous cell carcinoma were screened in saussurea involucrata, and new therapeutic targets were discovered
Authors: Zhang Dongdong , Zhang Tieying , Zhang Yao , Li Zhongqing , Li He , Zhang Yueyang , Liu Chenggong , Han Zichao , Li Jin , Zhu Jianbo
Published: September 2021

Purpose: Based on systemic pharmacology and network pharmacology, to evaluate the therapeutic effect of saussurea involucrata (SAIN) on lung adenocarcinoma and lung squamous cell carcinoma (LUAD&LUSC) through clinical sample genetic difference analysis and compound-target molecular docking, and discover new The target of prevention or treatment of LUAD&LUSC. Materials and methods: Using the TCM System Pharmacology Database (TCMSP) as the starting point for preliminary selection of ingredients and targets (OB≥30%, DL≥0.18, n=9), with the GDC database as the end point, using Cytoscape 3.8, TBtools 1.082, AutoDock 4.2.6, R 4.0.4, PyMol and other tools have conducted a preliminary screening of the ingredients and targets of SAIN. In order to further screen the effective ingredients and targets, we used clinical samples from LUAD and LUSC from TCGA and GEPIA to perform genetic difference analysis (n=6), and perform biological process (BP) analysis (FDR) on these targets. ≤0.05, n=6), KEGG pathway analysis (FDR≤0.05, n=6), protein interaction network (PPI) analysis (n=6) and compounds-targets-pathways network analysis (n=6), obtain biological processes, disease pathways and various compounds regulated by targets-the relationship between targets and pathways. Through the precise molecular docking of ingredients and targets, we further screened the targets of the effective ingredients of SAIN (affinity≤-7.0 kcal/mol, H-Bond dist≤3.0, n=6) and visualized the data, Then these targets were verified by using PSORTⅡ, CELLO and BUSCA databases for subcellular localization prediction (n=6). Finally, use the large amount of TCGA clinical data provided by Cbiportal for the prognostic survival analysis of LUAD and LUSC for the genes obtained through the screening. , And consult a large number of documents to verify the results.Results: After screening, comparing, analyzing and verifying a series of data, it is finally confirmed that there are three main active ingredients in SAIN. They are Quercetin, Luteolin and Kaempferol, which mainly act on 6 protein targets. The target mainly regulates 20 signal pathways including Pathways in cancer, Transcriptional misregulation in cancer, EGFR tyrosine kinase inhibitor resistance, Adherens junction, IL-17 signaling pathway, Melanoma, Non-small cell lung cancer and MicroRNAs in cancer. The preventive or therapeutic effects of LUSC. Conclusion: There are three active compounds of Q, L and K in SAIN, which play a role in the treatment and prevention of NSCLC by directly or indirectly regulating the expression of genes such as MMP1, MMP3 and EGFR.
Environmental quality standards for diclofenac derived under the european water framework directive: 1. Aquatic organisms
Authors: Leverett Dean , Merrington Graham , Crane Mark , Ryan Jim , Wilson Iain
Published: September 2021

Diclofenac is a nonsteroidal anti-inflammatory human and veterinary medicine widely detected in European surface waters, especially downstream from Wastewater Treatment Plants. Veterinary uses of diclofenac in Europe are greatly restricted, so wastewater is the key exposure route for wildlife. Proposed Environmental Quality Standards (EQS) which include an assessment of toxicity to aquatic organisms are under consideration by the European Commission (EC) to support the aims of the Water Framework Directive (WFD). The EC approach favours the use of a deterministic (single test value and an assessment factor) approach to the derivation of a direct toxicity EQS for diclofenac, resulting in an EQS of 0.040 µg L− 1 based on a single mesocosm study. In this paper, we discuss potential issues with this approach with respect to the EC’s own guidance on EQS derivation and derive an evidence-driven alternative EQS of 0.126 µg L− 1 using a probabilistic (Species Sensitivity Distribution) approach that accounts for all of the reliable and relevant data and is in accordance with the guidance. Europe-wide freshwater monitoring data for diclofenac are used in an indicative compliance assessment using the EC and the alternative evidence-driven EQS. The implications of using only some data to derive an EQS that does not adhere to the guidance, compared to a guidance compliant approach that uses all the data available is also discussed.
Adherence with COVID-19 Preventive Measures and Associated Factors Among Residents of Shashemane, Central Ethiopia
Authors: Tesfaye Adane , Asefa Banchiwosen , Gebremeskel Girum , Washo Asefa , Muche Temesgen
Published: September 2021

Introduction:Covid 19 pandemic can seriously affect African nations because of the weak health care system, crowding, poor hygiene in the cities, and the random mobility of people. Hospital-based interventions are not a good choice for resource-scarce countries which have shortages of hospital beds, ventilators, and oxygen; rather practicing preventive measures at a community level is the best strategy. There is a shortage of evidence about current public adherence with COVID-19 preventive strategies in Ethiopia, therefore this study helps to target health education messages to groups of populations with poor compliance to specific prevention measures, which also contribute to decreasing the magnitude and duration of the pandemic.Methods:A Community based cross-sectional study was done on 405 participants selected by systematic random sampling in Shashemane. Data was collected using A pretested structured tool comprising socio-demographic characteristics, knowledge, attitude, and adherence with COVID-19 prevention practice. Participants who practiced ≥ 75% of the COVID-19 preventive practices were labeled as having “good adherence”. Bivariate and multivariable logistic regression was used to determine the associated variables. Odds ratios along with 95%CI were estimated to identify associated factors and a level of statistical significance was decided at p -value less than 0.05.Result:The practice of COVID-19 preventive measures was 19.5%, (95% CI: 15–24.5%). Having a favorable attitude (AOR = 5, 95% CI: 3.3–8.41), having good knowledge of the disease (AOR = 3, 95% CI: 2.74– 9.3) and educational status (Diploma and above) (AOR = 5.5, 95% CI: 2– 9.39) were significantly associated factors with the practice of COVID-19 preventive measures.Conclusion:The Adherence to COVID-19 preventive practices was very low, educational status above Diploma, good knowledge, and Favorable attitude were the factors positively and independently associated with good adherence to Covid-19 prevention practices. Behavioral change communication and Strict government law and implementing it are highly required.
The impact of armed conflict on the prevalence and transmission dynamics of HIV Infection in Libya.
Authors: DAW Mohamed Ali , El-Bouzedi Abdallah Hussean , Ahmed Mohamed Omar
Published: September 2021

The interrelationships between HIV/AIDS and armed conflict are a complex phenomenon and studies are rarely devoted to this area of research. Libya is the second-largest country in Africa that has been evoked with war since NATO intervention in 2011. The country has also experienced one of the largest HIV outbreaks associated with the Bulgarian Nurses saga. The effect of the armed conflict on the dynamic spread of HIV is not well known. The objectives of this study were to determine the impact of armed conflict on the epidemiological situation of HIV infection in Libya and analyze the transmission dynamics of HIV strains during the conflict. We investigated the movement of HIV-infected people during the Libyan armed conflict and analyzed the HIV subtypes reported from 2011 to 2020 and followed up the infected cases all over the country. The patterns of HIV spread within the Libyan regions were traced and risk factors were determined during the conflict period. A total of 4539 HIV/AIDS patients were studied from the four regions during the Libyan conflict. Our data analysis indicated that Benghazi the biggest city in the Eastern region was the significant exporter of the virus to the rest of the country. Viral dissemination changes were observed within the country particularly after 2015. A major virus- flow from the Eastern region during the armed conflict associated with internally displaced people. This resulted in a dissemination of new HIV strains and accumulations of HIV cases in Western and Meddle regions. Although, there were no significant changes in the national prevalence of HIV/AIDS. Our data highlights the factors that complicated the spread and dissemination of HIV during the armed conflict which provides a better understanding of the interaction between them. This could be used to plan for effective preventive measures in tackling the spread of HIV in conflict and post-conflict settings.
Post COVID-19 Guillain Barre Syndrome in Immunocompromised Children - A report of two cases and review of literature
Authors: Goel Neha , Mehndiratta Sumit , Singh Amitabh
Published: September 2021

IntroductionSevere acute respiratory syndrome Coronavirus 2 (SARS-CoV 2) is a novel coronavirus that caused an outbreak since 31 December 2019. Although the most commonly noted symptoms were fever and respiratory illness, a wide variety of other symptoms have also been seen. There has been increasing number of cases of neurological manifestations of Covid –19. Further, there has been growing association between Covid-19 and Guillain Barre Syndrome (GBS).Case presentationIn this report, we present two cases of acute lymphoblastic leukemia affected by Covid-19 who after recovery from Covid-19 developed symptoms of GBS. They presented with complaints of bilaterally symmetrical ascending motor paralysis and were diagnosed with Guillain Barre Syndrome by electrophysiological tests and were started on intravenous immunoglobins for five days @ 0.4mg/kg/day after which the condition of both children gradually improved.ConclusionThis case report adds to the emerging evidence that suggests the association of GBS post Covid infections. COVID-19 can result in several autoimmune neurological phenomena including GBS. In the setting of the pandemic, COVID-19 as an underlying trigger should be considered in all immunologic phenomena. This applies to all patients, including children.
Surveillance of emerging infectious diseases in wild non-human primates in Kenya: Successes and challenges
Authors: Akinyi Mercy Y. , Kivai Stanislaus , Mbuthia Peris , Kiragu David , Wango Tim , Shikoli Cedrick , Ochola Lucy
Published: September 2021

Emerging infectious diseases (EIDs) originating from wildlife present a significant threat to global health, security, and economic growth, thus combatting their emergence is a public health priority. Humans and non-human primates (NHPs) exhibit a high degree of overlap in their genetic and physiological similarities, hence making them susceptible to majority of pathogens that can cross the primate species boundaries. However, efforts to understand the potential infectious disease-causing pathogens harbored by wild primate populations has lagged and is yet to be fully explored. Disease surveillance in wildlife to identify probable infectious disease outbreaks has remained a challenge especially in developing countries due to logistical and financial constrains associated with both periodic and longitudinal sample collection. Such loopholes have hampered the preparedness to handle the emerging infectious diseases whenever they arise. In this review we focus on successes, challenges, and proposed solutions for EID surveillance in non-human primate populations in Kenya. We discuss,1) mechanisms of cross species transmission of EIDs, 2) the role of NHPS in EID transmission, 3) results from past NHP pathogen surveillance projects in Kenya and 4) challenges and proposed solutions for NHP-EID surveillance. Finally, we propose that more studies need to include investigations into understanding how cross species transmission occurs in diverse NHP populations and how this impacts one health.
Dor pós-operatória em Endodontia: revisão de literatura
Authors: Sousa Tamires Vieira de , Cruz Jose Henrique de Araújo , Sousa Kamilla Alencar , Sarmento Tássia Cristina de Almeida Pinto , Rosendo Rosana Araújo
Published: September 2021

Introdução: A endodontia é um ramo da odontologia baseado na saúde do sistema de canais radiculares, promovendo limpeza destes, frequentemente associada a eventos de dor pós-operatória. Vários fatores têm sido sugeridos como propiciadores deste sintoma. Objetivo: Este trabalho visa reunir dados da literatura que possam explicitar a ocorrência e intensidade da sintomatologia dolorosa pós-operatória em endodontia e quais variáveis podem estar envolvidas neste processo. Material e Método: Utilizou-se de 43 artigos científicos retirados das bases de dados: SciELO, MEDLINE, Lilacs, PubMed, BBO e BVS, encontrados em português, inglês e espanhol, usando os descritores: Dor Pós-Operatória, Endodontia, Polpa Dentária; com restrição de período de 2009 a 2019. Resultados: A dor pós-operatória em endodontia é relatada em aproximadamente metade dos casos, sendo a dor pré-operatória um fator fortemente associado. O número de sessões clínicas não exerceu diferenças na dor, bem como o uso de diferentes técnicas de instrumentação avaliadas. Polpas vitais exercem maior incidência deste sintoma. Ampliação de forame demonstrou-se mais associada à dor, enquanto a execução da patência foraminal mostrou capacidade de não produzi-la. Hidróxido de cálcio, clorexidina e pasta de antibiótico mostraram-se importantes medicações intracanal, bem como hipoclorito de sódio, clorexidina e ácido etilenodiaminotetracético foram soluções irrigadoras satisfatórias. Conclusão: Todas as variáveis evidenciaram alguma relação com a dor pós-operatória em endodontia, no entanto não se exibiram de forma expressiva, sugerindo que mais estudos são necessários sobre este tema.
Positioning of the knot in the steel wire in relation to the tooth and the Erich bars. Technical note
Authors: Simões Gabriela Maffeis D’Assumpção , Berardi Rogerio Henrique , Ogoshi José Lineu Pereira , Horikawa Fernando Kendi , Snidei Iron Ricardo Machado , Shinohara Elio Hitoshi
Published: September 2021

Erich bar is a basic technique for restoring occlusal alignment in patients with facial fractures. Although this method is used worldwide, there is no description of what is the best way to stabilize the bar that should be anchored tooth to tooth with steel wire. We describe the method of stabilizing the bar of current use in our Service. We indicate the use of this technique because it stabilizes the bar and, in our opinion, it reduces the need to twist the knots during the patient's return.
Open tray impression technique using a silica-nylon mesh for splitting implants: a case report
Authors: Paes-Junior Tarcisio José de Arruda , Freitas Paolo , Nishioka Renato Sussumu , Nishioka Gabriela Nogueira de Melo , Nakano Leonardo Jiro Nomura
Published: September 2021

This article describes an alternative open tray technique for implant impressions using a novel reinforced silica-nylon mesh covered with acrylic resin as a splitting system in assembling the abutment complex. The purpose of the procedure is to simplify the technique and improve the resin contraction during clinical procedure, and also optimizes and reduces the chairside time for the patient. The clinical report was supported by an in vitro study where an analysis tool, Strain Gauge Analysis, was used to prove the clinical effectiveness of the technique. The peri-implant strain was determined on polyurethane casts with the torqued prosthesis, and statistically there was no difference in strain under torque of transfers or in the final prosthesis. The nylon mesh attached to acrylic resin represents a promising option for open tray impression technique, creating a resistant union to transfer in an excellent procedure time.
Tratamento cirúrgico de sialólito no ducto da parótida: relato de caso
Authors: Nogueira Emerson Filipe de Carvalho , Nascimento Yasmin Lima , Lôbo Maelly Vicente , Espíndola Rebeca Pereira , Sampaio Diogo de Oliveira , Araújo Fábio Andrey da Costa
Published: September 2021

Introdução: Os sialólitos são lesões mineralizadas nas glândulas salivares que causam obstrução total ou parcial do ducto, acometendo comumente a glândula submandibular. Sua abordagem varia de pouco invasiva à cirúrgicas, a depender do número, localização e dimensões dos cálculos. Objetivo: Esse estudo teve como objetivo relatar um caso clínico raro de sialólito no ducto da glândula parótida tratado através da remoção cirúrgica. Relato De Caso: Paciente compareceu ao ambulatório com história de dor e edema em face com 2 meses de evolução, referindo piora da sintomatologia após alimentação. Ao exame físico apresentou edema endurecido em região pré-auricular esquerda e ausência de drenagem no ducto da parótida ipsilateral. Foi realizado uma radiografia de tecidos moles com filme periapical, que revelou imagem radiopaca circunscrita sugestiva de um sialólito no ducto da glândula parótida esquerda. Assim, foi realizada excisão cirúrgica do cálculo seguida do reestabelecimento da patência ductal através da instalação de cateter venoso. Paciente evoluiu bem e segue em acompanhamento sem recidiva dos sinais e sintomas. Considerações Finais: O presente estudo revela que o diagnóstico precoce da sialolitíase e a escolha do plano de tratamento adequado estão associados a um bom prognóstico, e o reestabelecimento da patência ductal, quando danificado, é imprescindível para o sucesso do tratamento.
Neurological manifestations and pathophysiological mechanisms of Covid-19
Authors: Gaujac Cristiano , Amaral Regiane Cristina
Published: September 2021

Background - Severe acute respiratory syndrome coronavirus-2 is a novel, highly infectious coronavirus and the etiologic agent of Covid-19. The course of Covid-19 can range from mild flu-like symptoms to severe, life-threatening symptoms, especially when comorbidities are present. Increasing studies have reinforced the association between SARS-CoV-2 and various neurological manifestations, although the pathophysiological mechanisms remain uncertain. Objective - The aim of this paper was to briefly describe current findings on the relationship between SARS-CoV-2 pathophysiology and major CNS and Peripheral Nervous System (PNS) manifestations. Methods and Material - This work consists of a literature review based on the study of academic papers. To this end, the Pubmed platform was used to search for scientific articles, using the keywords: covid-19, coronavirus, physiopathology, neuronal symptoms. Results - out of 114,660 articles found, 94 were selected for this review. Conclusions - Periodic reviews collaborate in the constant updating and summarization of findings. Understanding the pathophysiology of SARS-CoV-2 on the SN and the link between the systems may lead to earlier and earlier diagnoses of neurological involvement, guide therapeutic management, prevent sequelae, and preserve lives.
Editorial: Systemic Perspectives on New Alignments During COVID-19: Digital Challenges and Opportunities
Authors: Laferrière Thérèse , Cox Margaret
Published: September 2021

This overview of the articles presented in this issue considers the digital challenges and opportunities of the systemic perspectives on new alignments resulting from the onset of the COVID-19 pandemic. New challenges and opportunities were addressed by the 13 working groups of EDUsummIT2019 prior to the pandemic. However, the evidence and analyses presented in this issue have built on those originally identified perspectives by reviewing recent (2020/2021) research, development and practice across many educational sectors and contexts. We have shown that the status quo in the majority of education systems across the world has been thrown out of kilter. This has resulted in new alignments needing to be made to take account of the enforced remote learning when schools have been closed and blended learning has become widely practised even at school level. The most prominent of these have been caused by changes in digital equity which consequently imposes new challenges to policy makers, teachers and learners. This special issue stimulates reflection in and on practice as well as help problematizing new research challenges.
Franchise business sustainability model: Role of conflict risk management in Indonesian franchise businesses
Authors: Prihandono Dorojatun , Wijayanto Andhi , Cahyaningdyah Dwi
Published: September 2021

Franchising is one of the most trustworthy strategic alliance formations to start or expand businesses. Like many other business formations, franchise businesses need sustainable and long-term running; these objectives can be reached by a proper relationship between partners – the franchisor and the franchisee – in the alliances. Both partners’ perspectives are valuable inputs to provide insight into understanding the sustainability of Indonesian franchise businesses. Furthermore, in any type of strategic alliances conflict is a risk that needs to be managed properly. This study aims to examine the relationships of determinants that influence franchise business sustainability. The determinants are risk management, trust, satisfaction, and sustainability. The study applies confirmatory factor analysis using structural equation modeling (SEM) AMOS software. Respondents in this study are franchisors and franchisees in the Indonesian retail and food and beverages (F&B) sectors, the study accommodates 204 respondents. Based on the analysis the study reveals that there is a positive relationship between risk management and satisfaction. Risk management also has a positive relationship with survivability; trust and satisfaction also have a positive relationship. Meanwhile, there is no relationship between satisfaction and survivability and the last relationship is between trust and survivability that has no positive relationship between the determinants. This study provides clearer insight to understand the relationships between determinants that influence franchise business survivability in Indonesia, especially based on both parties’ perspectives.
Employee engagement and best practices of internal public relations to harvest job performance in organizations
Authors: Nu Ngoc Ton Han , V. Nguyen Phuong , The Vuong Luan , Quynh Tran Hoa
Published: September 2021

Internal public relations are used to control the relationship between the organization and its employees. The paper explored whether and how internal public relations stimulate employees’ life satisfaction and job performance. The conceptual framework was built to link internal social media, perceived organizational transparency (POT), organizational identification, employee engagement, life satisfaction, and job performance. Using the hierarchical component model with employee engagement measured by job engagement and organizational engagement is a nascent point from this study. A mass survey was distributed to employees working in the aviation industry in southern Vietnam. Partial least squares structural equation modeling was used to analyze primary data from 193 valid respondents. It reveals that POT, internal social media, and organizational identification significantly positively impact employee engagement. It shows that employee engagement has significantly positive impacts on life satisfaction and job performance. It indicates that both organizational identification and POT are partial mediators intervening in the strong relationship between employee engagement and internal social media. It also indicates that life satisfaction is a partial mediator intervening the positive linkage between employee engagement and job performance. Practical implications and theoretical contributions were suggested for using internal public relations to enhance employees’ life satisfaction, and job performance.
AcknowledgmentThis study is funded by Vietnam National University of Ho Chi Minh City (VNU-HCMC) under grant number B2020-28-02.
Challenges and Solutions for Keeping Maternity and Gynecology Services Functioning Comprehensively in Secondary Level Health Care Facility in COVID-19 Pandemic Situation Using a Clinical Spproach
Authors: Biswas Jayanta Kumar , Lall Pratistha , Poddar Soumen Das , Srivastava Vikas , Nilakantan Ajith
Published: September 2021

OBJECTIVE: With the nationwide lockdown in India, and with a near-exclusive focus on the novel coronavirus disease (COVID-19) there has been a great deal of neglect in the management of other illnesses leading to significant mortality and morbidity. We aimed to assess the feasibility of keeping obstetrics & gynecology services in a secondary care hospital functioning (in terms of regional experiences and comprehensive patient care measures) in the COVID-19 pandemic situation using a clinical approach.
STUDY DESIGN: All policies of the World Health Organization and other international obstetrics- gynecological recommendations or guidelines were followed in keeping the services functional. Hospital data of obstetrics and gynecology services were maintained and compared with the previous year’s data of the corresponding period (January to December) through a retrospective observational study.
RESULTS: Compared to figures for 2019, in-patient admissions, surgeries, and daycare procedures performed, and deliveries conducted were reduced in total but almost approached previous levels. The number of out-patient attendance and gynecologic laparoscopic surgeries were significantly reduced mostly in the initial month of lockdown (April 2020) and thereafter. Only limited COVID-19 testing was done and there was no mortality in patients or health care workers (HCW) in the obstetrics and gynecological department.
CONCLUSION: COVID-19 pandemic had caused an unprecedented global healthcare crisis. The experience and data collected from our hospital in the study period validate the ‘clinical’ working protocol that enables comprehensive maternity and gynecology care at secondary level care centers even in a pandemic situation without adverse outcomes on patients or the hospital staff.
In memory of A.M. Zamyshliaev
Authors: Editorial Article
Published: September 2021

.
A Concise and Efficient CuI-catalyzed Synthesis of Diimino Dihydroquinazoline
Derivatives from Isocyanides and Guanidines Derivatives
Through Intramolecular C-H Activation
Authors: Nematpour Manijeh , Dastjerdi Hossein Fasihi , Mahboubi-Rabbani Mohammad
Published: September 2021

:

A novel series of diimino dihydroquinazoline derivatives were synthesized from isocyanides and guanidine analogs in quantitative yields by applying an efficient, inexpensive, one-pot copper-catalyzed intramolecular C-H activation reaction under mild conditions. The structures were confirmed on the basis of IR, 1HNMR, 13C NMR, mass spectral and elemental analysis data. The protocol offers advantages like short reaction time, simple workup process, high yields, and an environmentally benign methodology. Interestingly, better results (yield = 82%) were observed in terms of the yield obtained by using a mixture of CuI, Cs2CO3 and acetonitrile as the catalyst, base and solvent, respectively. The data also suggested that compound 5i is produced with the highest yield (87%) from the corresponding diisopropyl carbon diimide, 4-nitroaniline and phenyl isocyanide. Finally, a mechanistic explanation for the reaction promoted by cuprous iodide (CuI) was proposed on the basis of previous investigations and our experimental observations.
Energy Efficiency in IoT Based on Sensor Node Deployment Pattern
Authors: Gupta Sunita , Gupta Sakar
Published: September 2021

:

IoT becomes more complicated due to its large size. The existing techniques of
Wireless Sensor Networks (WSN) are not useful directly to the IoT; that is why using energyefficient
schemes for the IoT is a challenging issue. Due to battery-constrained IoT devices,
energy efficiency is of great importance. This paper gives an overview and broad survey on IoT,
WSN in IoT, challenges in IoT and WSN, energy-conserving issues and solutions and different
Node Deployment patterns. This paper addresses energy competence issues for green IoT by
proposing an energy-efficient heuristic for a regular and particular deployment scheme. QCMCSC
heuristic is implemented for Strip Based Deployment Pattern and analyzed in terms of
Energy Efficiency and Life Time of a sensor on Energy Latency Density Design Space, a
topology management application that is power efficient. QC-MCSC for Strip-based deployment
patterns and random deployment patterns are compared.
Management of Rhegmatogenous Retinal Detachment during COVID-19 Pandemic
Authors: AlAkeely Adel G. , Habeeb Abeer
Published: September 2021

Patients with primary Rhuegmatougenous Retinal detachment during COVID-19 pandemic were more likely to present late, have macula involving disease secondary and to show poor visual outcomes. Pneumatic Retinopexy (PR) is a procedure that eliminates the need for admission and limits the duration of contact with patients. Hence, more feasible during periods of shortage in hospital beds and medical personnel in the pandemic. In our experience, we successfully performed pneumatic retinopexy on two confirmed COVID-19 cases with favourable visual outcomes. We would recommend retina surgeons be familiar with such procedure as it may be a good alternative to conventional treatment while minimizing the risk of transmitting COVID-19.
Ultra-low dioxane in ethoxy sulphate products
Authors:   Desmet Ballestra, Sebastiani Ilio , Milicia Antonio , Adami Icilio
Published: September 2021

The progressive reduction of the permitted content of 1,4-dioxane in ethoxy sulphates presents an increased challenge for surfactant producers. This article discusses technical solutions that can be put in place based on the chemistry of the 1,4-dioxane molecule and its formation mechanism during surfactant production. Desmet Ballestra’s “ultra-low dioxane technology” is discussed in detail, with emphasis on the technical features, advantages, and achievable quality. Technologies for 1,4-dioxane degradation and disposal into water effluent streams are also illustrated.
The dynamics of jama (jamu madura-madurese traditional herbal medicine) in the viewpoint of public woman: a phenomenology study
Authors: Salat Sri Yunita Suraida , Ahmaniyah Ahmaniyah , Suprayitno Emdat
Published: September 2021

Background: With the progress and development of medicine that is currently happening, there are still many people in Sumenep who choose Madurese traditional herbal medicine in an effort to prevent and to cure disease, in the process of pregnancy, childbirth and the postpartum period. This habit was inherited from their ancestors. Jamu is supposed to provide benefits and safe with no side effects. People in Sumenep still consuming herbal medicine during postpartum period as habit.

Objectives: This study aimed to describe views and opinions of postpartum mothers on the puerperal herbal medicine that they consumed during the postpartum period.

Methods: This study exploring the local culture, postpartum mothers’ knowledge about postpartum herbal medicine and their perception about its benefits. This study design was qualitative study with a phenomenological approach with total participants were 20 postpartum mothers and their families and 2 postpartum herbal medicine makers. Data were collected by direct observation through in-depth interviews.

Results: The results showed 5 themes describing the dynamics of the Madurese traditional herbal medicine in the viewpoint of post-partum mothers, namely their reasons for consuming postpartum traditional herbal medicine, the form of the herbal traditional medicine consumed, their knowledge of postpartum herbal medicine, the benefits of postpartum traditional herbal medicine, and the mother's desire to consume the puerperal herbal medicine in the future.

Conclusions: It can be concluded that there was different viewpoint that described by postpartum women about consuming postpartum herbal medicine. In general, they found that postpartum herbal medicine had benefits directly in the recovery process of the postpartum period and increasing breast milk production.
Potencial agronómico, productivo, nutricional y económico de cuatro genotipos de maíz forrajero en el valle de Chancay, Perú
Authors: Maguiña-Maza Rufino Máximo , Francisco Perez Sharon Carolyn , Pando Cárdenas Gerardo Luis , Sessarego Dávila Emmanuel , Chagray Ameri Néstor Humberto , Pujada Abad Hilario Noberto , Airahuacho Bautista Félix Esteban
Published: September 2021

El objetivo de la investigación fue comparar las características agronómicas, productivas, nutricionales y económicas de cuatro genotipos de maíz forrajero: INIA 617 Chuska, M28T Marginal 28 Tropical, Atlas 777 e INIA 619 Megahíbrido, en el valle de Chancay - Perú. Para ello, se estableció cuatro repeticiones por genotipo; cada repetición en un surco de 29 m de longitud, con distanciamientos 0.85 m. entre surco, 0.30 m. entre golpe de siembra y utilizando tres semillas/golpe en cada repetición. Las características agronómicas se evaluaron a los 93 días de siembra, mientras que el rendimiento productivo, nutricional y económico fueron estimados a los 110 días post siembra. Los genotipos INIA 617 y M28 alcanzaron la mayor altura de planta, mientras que el N° hojas/planta y N° mazorcas/planta fueron similares en todos los genotipos. El mayor rendimiento de forraje verde, proteína, grasa y ceniza del genotipo atlas 777 se reflejó en su tendencia de mejor potencial lechero y utilidad. No hubo diferencias significativas para el rendimiento de materia seca entre los cuatro genotipos. Entre los genotipos cosechados en estadio maduro, la tendencia de mayor contenido en CNF del INIA 617 se relaciona con la tendencia de mejor potencial lechero, mientras la tendencia de mayor contenido en fibra del M28T sugiere menor disponibilidad de nutrientes y se relaciona con el menor potencial lechero mostrado.
Effect of virtual reality hypnosis on pain threshold, neurophysiological and autonomic biomarkers in healthy volunteers: a prospective randomized cross-over study. (Preprint)
Authors: Terzulli Claire , Melchior Meggane , Goffin Laurent , Faisan Sylvain , Gianesini Coralie , Graff Denis , Dufour André , Laroche Edouard , Chauvin Chloé , Poisbeau Pierrick
Published: September 2021

BACKGROUND

Virtual reality hypnosis (VRH) is a promising tool to reduce pain. However, VRH benefits on pain perception and on the physiological expression of pain still require further investigation.

OBJECTIVE

In this study, we characterized the effects of VRH on heat pain threshold in adult healthy volunteers and simultaneously monitored several physiological and autonomic functions.

METHODS

60 healthy volunteers were prospectively included to receive nociceptive stimulations. The first series of thermal stimuli consisted of 20 stimulations at 60°C (duration: 500 ms) to trigger contact heat evoked potentials (CHEPs). The second series of thermal stimuli consisted of temperature ramps (1°C/sec) to determine the thermal pain thresholds of the participants. Electrocardiogram, electrodermal conduction, respiration rate as well as the analgesia nociception index were also recorded throughout the experiment.

RESULTS

Data from 58 participants were analysed. There was a significant increase in pain threshold in VRH compared to NoVRH (p<0.001, Wilcoxon matched-pairs signed ranks). No significant effect of VRH on CHEPs and heart rate parameters was observed. Compared to control, VRH subjects display a clear reduction in their autonomic sympathetic tone as seen by the low number of non-specific skin conductance peak responses (p = 0.0007, 2-way ANOVA) and the analgesia nociception index increase (p = 0.0005; paired t-test).

CONCLUSIONS

The results obtained in this study support the idea that VRH administration to healthy volunteers is effective at increasing heat pain thresholds and impacts autonomic functions. As a non-pharmacological intervention, VRH has beneficial action on acute experimental heat pain. This beneficial action will now need to be evaluated for the treatment of other types of pain including chronic pain.
Performance of Light Weight Concrete with Coconut Shell and Fly Ash
Authors: Kulkarni Vani
Published: September 2021

Abstract: The major factor that affects the housing delivery is high cost of materials for any conventional concrete. This has lead to find an alternative. An attempt has been made to find an alternative by using partial replacement of coarse aggregate by coconut shell aggregate and cement by fly ash. This report provides the information obtained from a literature search. And also provides laboratory experiments on Cement, Sand, Coarse aggregate and Coconut shell. This project is done using partial replacement of coarse aggregate by coconut shell aggregate and cement by fly ash.10 % of fly ash was kept constant as replacement for cement. And Coarse aggregate was replaced by 5%, 10%, 15%, and 20% of coconut shell aggregate.30 concrete cubes of 150x150x150 mm size were casted and 3 cubes were tested after 7 days of curing and 3 cubes were tested after 28 days of curing for each percentage.30 concrete Cylinders of 150x300 mm size were casted and 3 Cylinders were tested after 7 days of curing and 3 Cylinders were tested after 28 days of curing for each percentage.15 concrete Beams of 100X100X500 mm size were casted and 3 beams were tested after 28 days of curing for each percentage. Two models were done using ANSYS Software using the same failure loads from the experimental part. Keywords: Light weight concrete, coconut shell, Fly-ash, experimental.
Analysis and Stabilization of Dredged Material Using Marble Dust for Its Potential Use in Sub-Grade
Authors: Altaf Hamid
Published: September 2021

Abstract: This research paper deals about the experimental study on the stabilization of dredged material for its potential use in sub-grade. Large amounts of sediments are dredged from rivers and lakes as a result of environmental dredging in India. These dredged materials have poor geotechnical properties and are treated as wastes, On the other hand, there is a huge demand of sub-grade materials due to the increasing number of highway construction projects, so therefore it forms the significant topic for research. The stabilization of dredged material by marble dust is considered as an environmentally friendly option and economical because both marble dust and dredged material are waste products. Marble dust is formed by the cutting and polishing of marble stone. Marble dust contains high amount of calcium, silica, alumina which aids in the stabilization of the dredged material. Thus, the use of DM as sub-grade material may be considered as an environmentally friendly and economical option. Keywords: Dredged material, stabilization, environmental dredging, Subgrade etc
REPRESENTASI “NAZAR” DALAM FILM INSYA ALLAH SAH KARYA BENNI SETIAWAN
Authors: Giovani Giovani
Published: September 2021

Pada saat ini kebudayaan dan sebuah realitas sosial adalah seuah ideologi yang sering direpresentaikan dalam sbuah film atupun media lainnya, tidak terlepas itu hanya untuk kepentingan individu maupun kelompok.  Representasi adalah sbuah penggambaran, perwakilan atau gambaran. Secara sederhana, representasi dapat diartikan sebagai gambaran mengenai suatu hal yang terdapat dalam kehidupan yang digambarkan melalui suatu media.Film Insya Allah Sah adalah salah satu dari sekian banyak film dan media televisi lainya yang  mengadopsi dan memasukan nilai-nilai dari sebuah realitas sosial, yang  mana di dalam film Insya Allah sah menggambarkan ulaung konsep Nazar yang terdapat di tengah masyarakat untuk dijadikan sebuah representasi dalam film. Penggambaran ulang Nazar yang muncul dan konsep pelaksanaan Nazar yang muncul dalam film Insya Allah Sah memberikan sebuah pesan terhadap masyarakat dalam menepati dan merealisasikan Nazar yang telah diucapan. Dalam kasus Representasi Nazar pada film Insya Allah Sah karya Benni steiawan , representasi yang di munculkan melibatkan karakter wanita yang memberikan efek hijrah pada seorang wanita dan memberikan pesan bahwa Sangat penting dalam menepati sebuah Nazar
BRANDING SANGGAR REOG SINGO BARONG PASAR GUNUNG KABUPATEN LANGKAT MELALUI PERANCANGAN LOGO
Authors: Bintarto Joko , Warhat Zainal , Waspada Agung Eko Budi
Published: September 2021

Penelitian ini berjudul Branding Sanggar Reog Singo Barong Pasar Gunung Kabupaten Langkat Melalui Perancangan Logo. Sanggar Reog Singo Barong merupakan Sanggar Reog yang sudah lama berdiri di Pasar Gunung Kecamatan Secanggang Hilai Hilir Kabupaten Langkat. Sejak berdiri tahun 1956 sampai saat ini sanggar ini belum mempunyai brand identity berupa logo, sehingga perkembangan Sanggar Reog Singo Barong mengalami hambatan misalnya permasalahan perizinan dan ketenarannya belum tertanam dalam pikiran masyarkat. Untuk itu salah satu solusi masalahnya adalah dengan Branding Sanggar Reog SIngo Barong melalui perancangan logo, Adapun branding melalui logo dibuat meningkatkan citra dan sekaligus sebagai identitas Sanggar Reog Singo Barong. Branding Sanggar berupa perancangan logo beserta aplikasinya spanduk, poster, kartu nama, mug, pin, stiker, kaos, x-banner, jam, stempel, kepala surat, amplop dan gantungan kunci. Semua media tersebut merupakan proses branding Sanggar Reog Singo Barong. Didalam perancangannya pesan yang akan ditanamkan dalam pikiran masyarakat sesuai dengan rasa kidung yang berarti penyampaian tradisi reog dalam memelihara dan mempertahankan tradisi reog. Dari pesan komunikasi tersebut, maka dirancanglah bentuk visual yang mampu sebagai branding dalam memberikan citra yang positif dipikiran masyarakat.
ANALISIS ELEMEN PEMBENTUK RUANG PADA CUSTOMER SERVICE UNIVERSITAS POTENSI UTAMA
Authors: Lestari Siti Indah
Published: September 2021

Ruangan merupakan tempat ataupun wadah yang memiliki nilai timbal balik yang sangat kuat serta tempat orang melakukan interaksi yang memberikan dampak reaksi dan aksi. Aksi dan reaksi manusia bisa dipengaruhi oleh elemen pembentuk ruangnya, elemen pembentuk ruang dapat menciptakan suasana dan karakter pada ruangan tersebut. Pada studi kasus ini ruangan yang akan di bahas yakni Customer Service Universitas Potensi Utama dimana merupakan tempat melayani pihak internal Universitas dan eksternal Universitas. Pengaruh suasana ruang pada Customer Service dapat memberikan kepuasan dalam menyelesaikan masalah dengan memuaskan pelayanan yang diberikan termasuk menerima keluhan atau masalah yang sedang dihadapi. Pada penelitian ini bertujuan mengidentifikasi elemen pembentuk ruang customer service Universitas Potensi Utama yang dapat mempengaruhi reaksi dan aksi pada pengguna ruang tersebut. Pada penelitian ini metode yang digunakan yaitu metode kualitatif, metode ini sebagai landasan penelitian yang dapat menghasilkan data deskriptif dari perilaku orang yang mengamatinya baik berupa lisan dan tulisan. Adapun bentuk penelitian yang digunakan adalah penelitian deskriptif, dimana jenis penelitian ini menjabarkan berupa fenomena-fenomena yang ada pada ruang lingkup studi penelitian tersebut baik yang bersifat alamiah maupun buatan. Fenomena ini banyak memiliki rupa seperti: kegiatan/aktivitas, karakteristik, perubahan serta fenomena lain yang berhubungan dengan fenomena lainnya.
INFOGRAPHIC SILSILAH SULTAN YANG PERNAH MEMERINTAH DI KESULTANAN DELI
Authors: Purba Rinanda , Irwansyah Irwansyah
Published: September 2021

Kesultanan Deli adalah salah satu dari empat Kesultanan Besar yang ada di Sumatera Utara. Nama Deli sendiri diambil dari sejarah Raja Deli I yakni Tuanku Gotjah Pahlawan yang merupakan keturunan dari Raja Delhi Akbar (Hindusta, India). Deli merupakan sebuah kerajaan dengan konsep Kesultanan, dimana pewarisan tahta akan dilanjutkan oleh keturunan laki-laki dari Sultan sebelumnya. ini dirasa penting untuk dipecahkan dan diberikan solusi dengan membuat sebuah buku infographic wisata sejarah Sultan-Sultan yang pernah memerintah di Kesultanan Deli. Tujuannya dapat digunakan oleh wisatawan dan masyarakat untuk lebih mengenal dengan baik dan mengetahui informasi tentang Sultan yang pernah memerintah di Kesultanan Deli dari Sultan pertama hingga Sultan saat ini. Dalam melakukan analisis penelitian ini menggunakan Teknik analisis 5W+1H. Dengan menggunakan media infographic lebih menarik dan kreatif agar dapat menarik minat masyarakat sehingga dapat dijadikan media promosi untuk memperkenalkan sejarah Istana Maimoon.
PERANCANGAN DESAIN INTERIOR KLINIK KECANTIKAN LANTAI 1 MENARA MAIMI
Authors: Panjaitan Sri Wahyuni
Published: September 2021

Perkembangan bisnis klinik kecantikan di kota besar seluruh Indonesia berkembang pesat dan memiliki jumlah yang banyak. Salah satu perkembangan bisnis klinik kecantikan di kota besar adalah Kota Medan. Kondisi ini membuat semakin bertambah pesaing produsen klinik kecantikan. Para pebisnis klinik kecantikan bersaing ketat untuk mencerminkan kelebihan masing-masing usaha klinik kecantikan. Setiap pebisnis klinik kecantikan berusaha untuk menarik perhatian dari setiap konsumen dan akan memberikan rasa kepuasan terhadap konsumen. Para pebisnis klinik kecantikan memiliki strategi dalam pemasaran bisnis klinik kecantikan agar dapat berjalan dan sukses untuk menghadapi persaingan bisnis klinik kecantikan tersebut, mendapatkan dan menambah konsumen, serta dapat mempertahankan konsumen tersebut. Strategi pemasaran yang bisa digunakan oleh pebisnis klinik kecantikan salah satunya adalah layanan lingkungan fisik (servicescape). Maka dari itu akan dirancangan desain interior Klimik Kecantikan.