bluuebunny/crossref_metadata_2025 huggingface dataset:
Relationship between Scabies and Quality of Life in Islamic Boarding School X Surabaya
Authors: Audhia Rizqita Salsabilla  , Zulfa Labibah
Published: June 2023

Quality of life is individual’s perception of their existence in life. A person’s quality of lide can be affected by several things, including scabies. This research was conducted to analyze the relationship between scabies and the quality of life of students in one of islamic boarding school in Surabaya. This research is a cross-sectional study with primary data obtained through scabies examination and quality of life measurement using WHOQOL questionnaire. The result of this study was that there was no relationship between scabies and quality of life (p=0,057).
Dynamically selected watermark insertion using machine learning
Authors: Soppari. Kavitha  , T Sri Vinay  , G Sai Teja  , P H Rohith
Published: June 2023

Watermarking is a process of embedding one image into another image, used to protect the image from copyright infringement; the main aim of this watermarking is to provide ownership assertion- only rightful owner can extract the watermark from image to prove the ownership. Day-to-day the attacks on digital content (like images) are increasing, but still the same traditional watermarking process is used to for content protection. In traditional watermark embedding process static watermarks are used at the source which may lead to compromise of algorithm. To avoid this, in this paper a very new way of watermarking is introduced with the help of object detection, along with the concept of content-related watermarking by dynamically selecting the watermark image.
KaSAYSAYan: The integration of Philippine history as an interactive and informative mobile game application using unity game engine
Authors: CENTENO CRISELLE J  , MASANGKAY MIGUEL T  , MENDOZA HANNAH ROSE S  , MERCADO MARK ANTHONY S  , NULUD MARY GRACE D  , PACHECO MA SOFIA I
Published: June 2023

A positive outlook on learning is crucial in achieving one’s success. An apparent thing is that students lose motivation in learning Philippine History. They either find it hard to understand, or end up forgetting what they have learned when time goes by. The aim of this study is to create an Android-based adventure trivia game that teaches students about the Philippines while making it interactive. The content of the game is directly referenced from learner’s modules already implemented into the elementary curriculum.
Road construction analysis using regression technique
Authors: JHERIMAE C. ANCHETA  , PRIMO IVAN D. LAZO  , LLOVELYN B. MEDINA  , CRISELLE J. CENTENO  , ARIEL ANTWAUN ROLANDO C. SISON  , MARK ANTHONY S. MERCADO
Published: June 2023

Estimating cost in construction is important to the city's design and planning management hence, the construction cost estimate must not be overpriced which may cause corruption or underpricing that leads to unreliable or low-quality road projects. The total estimated cost is only valid in the same year it was proposed because of the inflation rate the costs may change. The researchers applied Multiple Linear Regression technique in predicting total estimated cost for road construction analysis. The model is evaluated by the means of R-squared to determine the variables if they are correlated or overfitting. The calculated R-squared is equals to 0.696598 with the predictor variables (x1 & x2) Roadbed width and Net length and it means that the predictors (Xi) explain 69.7% of the variance of Y. The higher the R-squared result, the better fit it is for the Multiple Linear Regression model. It also shows that X1 and X2 are significant predictor variables. The coefficient of multiple correlation (R) is equals to 0.834624 and it means that there is a very strong correlation between the predicted data and the observed data whereas the dependent variable (y) is the Estimated cost. CCS CONCEPTS: Multiple Linear Regression • Construction Estimation • Engineering
Breastfeeding in peripartum cardiomyopathy mothers: A systematic review
Authors: Dike Izza Maulaadianovi  , Fatimah Zahra Almashur
Published: June 2023

Introduction: Peripartum cardiomyopathy (PPCM) develops around the end of pregnancy or in the initial months after delivery. PPCM is induced by vasculotoxic chemicals secreted from the placenta and pituitary. Prolactin is one of these hormones that could be harmful. The maternal pituitary release prolactin in response to breastfeeding. The advantages of nursing for both mother and child must be taken seriously while deciding whether to breastfeed with PPCM. This systematic review aims to analyze the existing scientific evidence on breastfeeding in PPCM patients. Method: To ensure comprehensive retrieval of relevant research we search the following key databases: PubMed and ScienceDirect through 1000 for peer reviewed articles (in all languages) evidence related to breastfeeding in peripartum cardiomyopathy. Results: The studies suggest that PPCM influenced by the hormone prolactin which related to breastfeeding. Therapy of prolactin inhibitors is given to inhibit the worsening of PPCM patients, but with side effects patients cannot provide exclusive breastfeeding. From the study, breastfeeding has no significant effect on the LVEF of mothers with PPCM, but in PPCM conditions that are not well compensated, breastfeeding is not recommended and patients should undergo therapy with bromocriptine. Conclusion: Breastfeeding and bromocriptine go opposite but both have benefits for PPCM patients, consideration for breastfeeding or bromocriptine administration must considering the patient's condition. Administration of bromocriptine for certain conditions such as severe PPCM can accelerate LV function recovery. There will be side effects for both children and mothers who are not breastfed.
Abroma augusta (L.) L. f.: An ethno pharmacological review of its traditional uses and modern applications
Authors: Rakesh Goswami  , Priyajit Chatterjee  , Tanmoy Sinha
Published: June 2023

Abroma augusta (L.) L. f. has been used as traditional medicine by tribal women in India, Bangladesh forms ancient times. Ayurvedic medicine, derived from herbal plants is used to reduce the gamble effects of the synthetic drugs. In homeopathy, it has been using successfully for a long period. Major Phytochemicals such as, Taraxerol, Friedelin, β-Sitosterol, α-Amyrin, Lupeol, Octacosanol, have potentialities to control diabetes, anti-inflammation, gynecological disorders etc. Root extract has given fruitful effect in menstrual disorder. It has anti-fertility activity, and it is a prominent uterine tonic. In gonorrhea treatment, leaf and stem extract in cold water is very effective. Acetone extract of leaf showed high anti-microbial effect against Gram-positive bacteria. Simultaneously, acetone leaf extracts shown anti-fungal activity against Candida albicans, Rhizopus oryzae, Aspergillus fumiguts. According to various reports regarding its phytochemical profiling and medicinal properties, it can be said that Abroma augusta should be used broadly for future drug development programmed.
HUBUNGAN SIKAP KERJA DENGAN KELELAHAN OTOT PUNGGUNG PADA KARYAWAN PROSES PACKING PT. BAGINDO TUBAN
Authors: Utami Nizal Dwi , Syarifah Has, S.KM., M.Epid Dwi Faqihatus
Published: June 2023

Sikap kerja yang berdiri secara continue dapat sering menimbulkan nyeri pada otot punggung dan jika diabaikan tanpa pemulihan yang cukup akan menciderai sistem rangka (musculoskeletal disorders).

Tujuan penelitian menganalisis hubungan sikap kerja dengan kelelahan otot punggung pada karyawan proses Packing PT. Bagindo Tuban. Desain penelitian adalah analitic observasional dengan pendekatan cross sectional. Populasi adalah seluruh karyawan bagian proses packing PT. Bagindo Tuban sejumlah 126 orang. Jumlah sampel sebanyak 96 orang diambil dengan random sampling. Variabel bebas penelitian ini adalah sikap kerja, sedangkan variabel terikat yaitu kelelahan otot punggung. Instrumen yang digunakan penelitian ini adalah lembar kuesioner. Analisis menggunakan uji Chi-Square pada tingkat kepercayaan 95% (p<0,05). Hasil menunjukkan bahwa sikap kerja karyawan sebagian besar (60,4%) kategori risiko tinggi dan mengalami kelelahan otot punggung sebagian besar (56,3%) kategori sedang. Ada hubungan sikap kerja dengan kelelahan otot punggung pada karyawan proses packing PT. Bagindo Tuban dengan nilai p = 0,000 < 0,05. Penerapan sikap kerja dinamis (duduk, berdiri, membungkuk, tegap) dalam satu waktu dalam bekerja dapat memberikan keuntungan pada bagian sistem muskuloskeletal
Comparing Symmetric-Asymmetric Decentralization for Reducing Regional Tension: Indonesia and Thailand Experience
Authors: Khairul Muluk M. R. , Anantanatorn Anurat
Published: June 2023

In recent years, the growing number of public administration literature has concerned the effectiveness of decentralization to deal with ethnic conflicts. This issue is rising up due to the several failure reports of decentralization to manage the social conflicts and regional tension that possibly evolve into secessionism. This paper intended to explore the performance of symmetric and asymmetric decentralization to manage social conflicts that occurred in Indonesia and Thailand. This descriptive study was conducted through a qualitative approach and strengthened by analytical thinking exposure. Papua province, Indonesia, and some provinces in southern Thailand had been selected as the case study due to their political decision for implementing asymmetric and symmetric decentralization to manage ethnic conflict in each region. The result shows that either symmetric or asymmetric decentralization might be thought of as one of the viable solutions to managing social conflicts. However, both of these decentralization configurations may generate pros and cons impact. It is suggested that policy makers recognize the consequence of each implementation to consider appropriate decision- making. The analysis of this paper shows that symmetric decentralization tends to promote effectiveness and efficiency while asymmetric decentralization will be closer to tolerance and equality.
The The Impact of the E-Government Development Index (EGDI) on the Worldwide Governance Indicator (WGI) in European Union Countries
Authors: Sophia Yuliantini Lisa , Nurmandi Achmad
Published: June 2023

This study aims to analyze the impact of the e-Government Development Index (EGDI) on the Worldwide Governance Indicator (WGI) in European Union member countries. The EGDI is an index measurement that displays conditions related to the development of e-Government implementation in the member country of the United Nations, while the WGI is a series of governance indicators issued by the world bank that measures six dimensions of governance. The research method used in this research is a mixed method with collecting and analyzing data quantitatively by using Smart PLS 0.3 version, then collecting qualitative data analysis data by using qualitative methods collecting data from relevant scientific articles. The data sources for this research were obtained from the official website of the EGDI, the official website of the WGI, and literature studies of relevant scientific articles. The result of this study shows that the implementation of e-Government based on EGDI data in European Union countries has no impact on the six indicators of WGI as a whole. This is based on the results showing that the influence of the EGDI of European Union member countries on corruption control, government effectiveness, and voice of accountability is accepted, while the impact of the EGDI of European Union member countries on political stability and the absence of violence/terrorism, the quality of regulation and the rule of law is rejected. This research contributes to complement existing research by looking at the impact of implementing e-Government in European Union countries. This research is expected to be a reference in studying the implementation of e-Government in European Union countries so that it can be implemented effectively and efficiently.
DYNAMICAL SYSTEM FOR EBOLA OUTBREAK WITHIN QUARANTINE AND VACCINATION TREATMENTS
Authors: Nurwijaya Sugian , MA Ratnah Kurniati , Sugiarto Sigit
Published: June 2023

Ebola Virus Disease (EVD) is an infectious disease with a high mortality rate which is caused by the virus from the family of Filoviridae, genus of Ebolavirus. Therefore, this research works on the developing model of Ebola disease spread with SLSHVEQIHR type. The purpose of this study is to analyze the spread of Ebola disease with the treatments, which are quarantine and vaccination. Then determine the equilibrium point and basic reproduction number (R0). There are two equilibrium points, the disease free equilibrium point and the endemic equilibrium point. The analysis results in the model show that if R0<1 than the disease free equilibrium point is locally asymptotically stable. If R0>1 than the endemic equilibrium point is locally assymptotically stable. Numerical simulations are performed to show the population dynamics when R0<1and R0>1.
G-OPTIMAL DESIGN OF NON-LINEAR MODEL TO INCREASE PURITY LEVELS OF SILICON DIOXIDE
Authors: Wulandari Nindya , Erfiani Erfiani , Irzaman Irzaman , Syafitri Utami Dyah
Published: June 2023

Silicon Dioxide (SiO2) is one of the most abundant minerals found on earth. SiO2 is widely used in various fields, so its availability as a finite natural resource diminishes. A purity procedure can raise the purity of low-quality silica by altering the temperature and rate of temperature rise. This study aims to obtain the best design for increasing SiO2 levels—the G-optimal design on a non-linear model using the Variable Neighborhood Search (VNS) algorithm. The VNS algorithm employs two types of neighborhoods, one acquired by replacing one design point with a candidate set and the other by replacing two design points with two points in the candidate set. The model used to increase silicon dioxide's purity is a non-linear model that follows the exponential decay distribution. The best design points obtained from the G-optimal design on the relationship between temperature (oC) and the rate of temperature increase (oC/min) 800 oC to 900 oC is a pair of points 800 oC and 1,67 oC /min, 800 oC and 2,17 oC/min, 815 oC and 2,50 oC/min, 825 oC and 2,00 oC/min, 845 oC and 2,34 oC/min, 895 oC and 3,34 oC/min 900 oC and 3,50 oC/min with a G-efficiency of 96,41%.
BIPARTITE GRAPH ASSOCIATED WITH ELEMENTS AND COSETS OF SUBRINGS OF FINITE RINGS
Authors: Muhammad Hubbi , Qonita Niswah , Wahyu Fibriyanti R A , Susanti Yeni
Published: June 2023

Let  be a finite ring. The bipartite graph associated to elements and cosets of subrings of  is a simple undirected graph  with vertex set , where  is the set of all subrings of , and two vertices  and  are adjacent if and only if  In this study, we investigate some basic properties of the graph . In particular, we investigate some properties of , where  is the ring of matrices over  Also, we study the diameter of the bipartite graph associated to the quaternion ring
RAINBOW VERTEX-CONNECTION NUMBER ON COMB PRODUCT OPERATION OF CYCLE GRAPH (C_4) AND COMPLETE BIPARTITE GRAPH (K_(3,N))
Authors: Yahya Nisky Imansyah , Fatmawati Ainun , Nurwan Nurwan , Nasib Salmun K
Published: June 2023

Rainbow vertex-connection number is the minimum colors assignment to the vertices of the graph, such that each vertex is connected by a path whose edges have distinct colors and is denoted by . The rainbow vertex connection number can be applied to graphs resulting from operations. One of the methods to create a new graph is to perform operations between two graphs. Thus, this research uses comb product operation to determine rainbow-vertex connection number resulting from comb product operation of cycle graph and complete bipartite graph  & . The research finding obtains the theorem of rainbow vertex-connection number at the graph of  for  while the theorem of rainbow vertex-connection number at the graph of  for  for .
GENERALIZED CONFIRMATORY FACTOR ANALYSIS FOR KNOWING IMPACT OF KNOWLEDGE, ATTITUDES, AND BEHAVIORAL FACTORS HIV/AIDS IN INDONESIA
Authors: Rahmi Nur Silviyah , Astutik Suci , Astuti Ani Budi , Muhammad Alifiandi Rafi , Maisaroh Ulfah , Handayani Sri
Published: June 2023

The cumulative number of detected HIV/AIDS cases in the January – March 2021 period is 9,327, consisting of 7,650 HIV and 1,677 AIDS reported by 498 districts and cities from 514 districts and cities in Indonesia. Human Immunodeficiency Virus (HIV) is the virus that causes Acquired Immunodeficiency Syndrome (AIDS). Several factors that influence the spread of HIV/AIDS include knowledge, attitudes and behavior about HIV/AIDS. Someone who gains knowledge about HIV/AIDS will have high self-confidence and a positive outlook on life and be more optimistic in taking HIV/AIDS prevention actions. The main objective of this study is to determine the influence of external factors which include demographic, social and economic aspects, as well as internal factors which include knowledge, attitudes and behavior to the level of transmission of HIV/AIDS. By using the CFA approach, it can be seen which indicators have the greatest influence on the latent variables of knowledge, attitudes, and behavior or called loading factors. The data used is secondary data from a 5-year survey from the Central Statistics Agency, namely the 2017 Indonesian Demographic and Health Survey (IDHS) published at the end of 2018. The CFA results show that the P11 variable (about known infections) has the largest loading factor value, which is 0.613 in the variable. . hidden. knowledge. In the latent variable of attitude, the S1 variable (about identifying how the respondent knows someone is infected with HIV-AIDS) has the largest loading factor value of 0.514. While the behavioral latent variable, the variable R8 (whether men have been infected with sexually transmitted diseases (STI) with symptoms) has the largest loading factor value, which is 0.954.
APPLICATION OF FUZZY TIME SERIES WITH FIBONACCI RETRACEMENT FOR FORECASTING STOCK PRICE PT. BANK RAKYAT INDONESIA
Authors: Dwi Miranda Anggel , Yosmar Siska , Damayanti Septri
Published: June 2023

Stock can be defined as securities that indicate the ownership of a person or legal entity to the company issuing the shares. Good stocks for long-term investment are stocks that have good fundamentals and large market capitalization. The purpose of investing is to make a profit. In investing in stocks, investors need to know the risk management that can affect the ups and downs of a stock. Forecasting or forecasting is an analysis to predict everything related to the production, supply, demand, and use of technology in an industry or business. One of the forecasting methods is using fuzzy time series. The primary purpose of fuzzy time series is to predict time series data that can widely use on any real-time data, including capital market data. In this study, we will discuss the evolution of the time series model in overcoming fluctuations that often occur in stock prices by using a fuzzy time series that combines a stock analysis approach, namely Fibonacci retracement. The stock data used in this study is the close price of BBRI for October 2021 to March 2022. Forecasting results for 1 April 2022 are IDR 4660.49 with a Mean Absolute Percentage forecasting accuracy value of 1.034%.
COMPARISON OF RESAMPLING EFFICIENCY LEVELS OF JACKKNIFE AND DOUBLE JACKKNIFE IN PATH ANALYSIS
Authors: Papalia M. Fikar , Solimun Solimun , Nurjannah Nurjannah
Published: June 2023

The assumption of normality is often not fulfilled, this causes the estimation of the resulting parameters to be less efficient. The problem with assuming that normality is not satisfied can be overcome by resampling. The use of resampling allows data to be applied free of distributional assumptions. In this study, a research simulation was carried out by applying Jackknife resampling and Double Jackknife resampling in path analysis with the assumption that the normality of the residuals was not fulfilled and the number of resampling was set at 100 with the degree of closeness level of relationship between variables consisting of low closeness, medium closeness, and high closeness. Based on the simulation results, resampling with a power of 100 can overcome the problem of unfulfilled normality assumptions. In addition, the comparison of the relative efficiency level of the resampling jackknife and double jackknife in the path analysis obtained by the resampling double jackknife has more efficiency than the resampling jackknife
APPLICATION OF THE BLACK SCHOLES METHOD FOR COUNTING AGRICULTURAL INSURANCE PREMIUM PRICE BASED ON RAINFALL INDEX IN KAPUAS HULU REGENCY
Authors: Marola Geby , Satyahadewi Neva , Andani Wirda
Published: June 2023

High-intensity rainfall is one of the factors that can interfere with the state of agriculture. Agricultural insurance is an insurance that can be used to reduce risks related to agricultural losses such as rice production. Climate-based agricultural insurance is a management of climate-related risks. This study aims to determine the rainfall index and calculate the value of agricultural insurance premiums based on the climate index (rainfall) in Kapuas Hulu Regency using the Black Scholes method. In calculating the value of agricultural insurance premiums based on the rainfall index, it starts by calculating the value of the correlation coefficient between rainfall and rice production. Then the value of the rainfall index is obtained, which then the value of the index is tested for lognormality to meet the assumptions on the Black Scholes method, after which it calculates the ln return value of the index value obtained, the last step is to calculate the value of agricultural insurance premiums. Based on case studies, the results obtained are when the risk-free interest rate is 3.5% and rainfall is 54.23 mm the premium paid is Rp 2,386,824 and when the rainfall is 75.39 mm the premium paid is Rp 3,898,142. If the risk-free interest rate is 4% and the bulk is 54.23 mm, the premium paid is IDR 2,383,842, and when the rainfall is 75.39 mm the premium paid is IDR 3,893,272. When the risk-free interest rate is 5% and rainfall is 54.23 mm the premium paid is Rp 2,377,890 and if the rainfall is 75.39 mm the premium paid is Rp 3,883,551. So, the higher the rainfall, the greater the premium value payment. If the risk-free interest rate gets bigger then the premium payment will be smaller.
COVID-19 PROJECTIONS ON JAVA AND BALI ISLANDS INVOLVING VACCINATION AND TESTING INTERVENTIONS USING VARI-X MODEL
Authors: Ibrahim Riza Andrian , Ruchjana Budi Nurani
Published: June 2023

The Indonesian government implemented the policy of increasing vaccination and testing of Covid-19 for travel from or to the Java and Bali Islands to reduce the Covid-19 projected spread in there. As participation in these efforts, this study aims to project the Covid-19 spread measured by the active case rates by involving the intervention of vaccination and testing of Covid-19 in the two islands. Projections are performed using a vector of autoregression integrated with the exogenous variables (VARI-X) model. This model is used because it can simultaneously project the Covid-19 spread in the two islands by involving interventions of vaccination and testing of Covid-19 as exogenous variables. The most suitable model obtained is VARI-X (4, 2, 0). The mean-absolute-percentage error (MAPE) of the model for the Java and Bali Islands is 5.3027% and 3.0301%, respectively. Based on the MAPE value, the model is very accurate for projecting the future Covid-19 spread on the two islands. This accuracy can be seen practically from the Covid-19 spread projection results in the next four days, which are very close to the actual data. This research is expected to help the Indonesian government project the spread of Covid-19 on the Java and Bali Islands.
CABLE NEWS NETWORK (CNN) ARTICLES CLASSIFICATION USING RANDOM FOREST ALGORITHM WITH HYPERPARAMETER OPTIMIZATION
Authors: Saputro Dewi Retno Sari , Sidiq Krisna
Published: June 2023

The growth of news articles on the internet occurs in a short period with large amounts so necessary to be grouped into several categories for easy access. There is a method for grouping news articles, namely classification. One of the classification methods is random forest which is built on decision tree. This research discusses the application of random forest as a method of classifying news articles into six categories, these are business, entertainment, health, politics, sport, and news. The data used is Cable News Network (CNN) articles from 2011 to 2022. The data is in form of text and has large amounts so good handling is needed to avoid overfitting and underfitting. Random forest is proper to apply to the data because the algorithm works very well on large amounts of data. However, random forest has a difficult interpretation if the combination of parameters is not appropriate in the data processing. Therefore, hyperparameter optimization is needed to discover the best combination of parameters in the random forest. This research uses search cross-validation (SearchCV) method to optimize hyperparameters in the random forest by testing the combinations one by one and validating those. Then we obtain the classification of news articles into six categories with an accuracy value of 0.81 on training and 0.76 on testing.
IMPLEMENTATION OF THE DBSCAN METHOD FOR CLUSTER MAPPING OF EARTHQUAKE SPREAD LOCATION
Authors: Bariklana Muhammad , Fauzan Achmad
Published: June 2023

West Java area is located on the Pacific Circum and Mediterranean Circum routes, this causes West Java area to be an unstable area that is characterized by many active working volcanoes and frequent earthquakes. An analysis of the grouping of earthquake data in West Java Province area is urgently needed. The purpose of this study was to classify areas based on the density of earthquake occurrence areas in West Java using Density-Based Spatial Clustering of Application with Noise (DBSCAN). The population in this study are all earthquake events occurred in 2021. While the sample used in this study is data on the location of the distribution of earthquakes in West Java Province in 2021 taken from the BMKG online data website at dataonline.bmkg.go.id. This research began with nearest-neighbor analysis to see patterns of data distribution. If the data distribution pattern is grouped, then DBSCAN analysis can be continued. The DBSCAN algorithm uses a combination of parameters, namely minimum points (MinPts) and epsilon (Eps). Cluster results are evaluated using the silhouette coefficient. Then, in this study, deeper data exploration was carried out in three ways, namely: (1) Clustering based on the highest silhouette value, (2) clustering by lowering the MinPts value, and (3) clustering based on the smallest upper limit (supremum) value of the silhouette coefficient. The data exploration here aimed to form more clusters while still considering the silhouette coefficient value limits so that there are more areas prone to earthquakes but also maintaining the validity of the results obtained. Next, determine the best cluster results by comparing the cluster results obtained. The best cluster results were obtained at Eps=10000 and MinPts=3 which formed 12 clusters with a silhouette coefficient value of 0.713, which means that the clusters have a strong structure. It is hoped that the information regarding the grouping of areas where earthquakes frequently occur can be used as a form of earthquake disaster mitigation and minimize the impact of losses due to the earthquake.
DYNAMICAL SYSTEM FOR COVID-19 OUTBREAK WITHIN VACCINATION TREATMENT
Authors: Sugiarto Sigit , MA Ratnah Kurniati , Nurwijaya Sugian
Published: June 2023

Covid-19 is a deadly infectious disease that occurs throughout the world. Therefore, it is necessary to prevent the transmission of Covid-19 such as vaccination. The purpose of this research is to modify the model of the spread of the Covid-19 disease from the previous model. The equilibrium points and the basic reproduction number ( ) of the modified model is determined. Then a stability analysis was carried out and a numerical simulation was carried out to see the dynamics of the population that occurred. The analysis performed on the model obtained two equilibriums, namely the disease-freeequilibrium and the endemic equilibrium. Disease-free equilibrium are locally asymptotically stable if . Meanwhile, the endemic equilibrium is locally asymptotically stable if . The numerical simulation results show the same results as the analytical results.
NET SINGLE PREMIUM ON CRITICAL ILLNESS INSURANCE WITH MULTI-STATE MODEL
Authors: Taraly Inggriani Millennia , Satyahadewi Neva , Perdana Hendra , Tamtama Ray , Aprizkiyandari Siti
Published: June 2023

The chances of someone getting a disease or suffering from a critical illness are very large, especially when they get older, the chances of getting a critical illness will be higher. A guarantee of the future is indispensable if a person suffers from a critical illness at any time and requires considerable costs to undergo treatment. Insurance is one of the right choices and is beneficial for people with critical illnesses. In this study, the calculation of Critical Illness insurance premiums was carried out to determine the value of premiums that must be paid by a person when suffering from a critical illness. The types of critical illnesses used include cancer, heart disease, stroke, kidney failure, diabetes mellitus, and hypertension. Health insurance that protects insureds suffering from critical illnesses is Long Term Care insurance with the Annuity as A Rider Benefit product. The multi-state model is used to determine the probability of a person suffering from a critical illness. The benefits obtained are in the form of death compensation, and treatment costs when the insured is diagnosed with a critical illness. The data used are data on the prevalence of critical illnesses and the percentage of deaths due to critical illnesses. In this study, we will compare the amount of premium that must be paid by the insured with different interest rates, gender, coverage period, and age. The higher the age at the beginning of following the insurance, the higher the premium. The higher the interest rate during the payer's period, the lower the premium.
CROSS PRODUCT OF IDEAL FUZZY SEMIRING
Authors: Abdurrahman Saman
Published: June 2023

If one of the axioms in the ring, namely the inverse axiom in the addition operation, is omitted, it will produce another algebraic structure, namely a semiring. Analogous to a ring, there are zero elements, ideal (left/right) in a semiring, and the cross product of the semiring ideal. The analog of the fuzzy semiring has zero elements, ideal (left/right), and the cross product of the semiring fuzzy ideal associated with the membership value. This paper will discuss the cross-product of two (more) fuzzy ideals from a semiring. Furthermore, the cross-product of two (more) fuzzy ideals from a semiring will always be a semiring fuzzy ideal. But the converse is not necessarily true.
Hankalan maailman kulttuuriteoriaa
Authors: Salonen Tuukka
Published: June 2023

Lauren Berlant 2022: On the Inconvenience of Other People. Durham & London: Duke University Press. 238 s.
Kirjallisuus eläimiä sijaistamassa
Authors: Ääri Helinä
Published: June 2023

Pirjo Suvilehto 2022: Inspiroivat ja parantavat eläimet. Helsinki: Avain, 200 s.
Reconstructing a Site of Memory: Korolev Old Believers’ Prayer House
Authors: Vladimir Vladimirovicn Petrankin
Published: June 2023

This article is dedicated to a little studied problem of the 19th century Old Believers’ prayer houses localization on the cultural map of St. Petersburg. The theoretical and methodological basis of the research is Pierre Nora’s theory of lieux de mémoire, which shows the process of memory revival in spite of the history of oblivion. An overview of the most significant loci in the history of a historical and cultural phenomenon of Old Believers’ Saint-Petersburg was undertaken. There were presented data from various sources casting light on the circumstances of the Old Believers’ Korolev Prayer House functioning and closure, based on the analysis of which an attempt to relate this significant site of memory in the cultural history of St. Petersburg to a specific building in urban sprawl was undertaken for the first time. Interdisciplinary culturological methodology makes it possible not only to verify the address of the prayer house, which has not been considered determined with adequate accuracy until now, but also to raise an issue of studying the cultural history of the Old Believer St. Petersburg at the Pushkin era.
THE EFFECT OF THE UNITED STATES PRESIDENTIAL POLICY ON TÜRKIYE–IRAN RELATIONS IN 1970s
Authors: OZDEMİR Secil
Published: June 2023

The American Presidential Doctrines play a crucial role in international politics because they provide a general strategy for United States’ (U.S.) allies to follow. The United States' international policies, like the policies of all states, are complicated and broad-based. Presidential doctrines, on the other hand, reveal a basic strategy framework.

This study examined the events that occurred in the axis of Iran-Türkiye-Northern Iraq from President Richard Nixon to Jimmy Carter's administration and investigated the main outline of the American presidential doctrines that focused on the 1970s.

Poppy cultivation, the Cyprus issue, and the embargo crisis, which caused the crisis between Türkiye and the US in the 1970s, together with the policies implemented by the US to maintain balance in Northern Iraq and Iran, were all evaluated with a holistic approach.

In this study, it was determined that the international crises of the 1970s engendered a significant level of mistrust between regional countries, specifically in relation to the United States, as well as among various regional actors. During this time, the United States implemented a policy of supporting the Northern Iraq region and Kurdish elements in order to create a balance of power between Iran and Türkiye. This policy had the consequence of increasing feelings of insecurity among neighboring countries, but also created opportunities for non-regional actors to devise new strategies.
Vírgenes, madres y apóstoles de la moral. La Asociación de Mujeres de la Acción Católica Argentina durante las décadas de 1930 y 1940
Authors: Bertolotto María Alejandra
Published: June 2023

Este trabajo analiza el activismo y los discursos de la Asociación de Mujeres de la Acción Católica Argentina (AMAC) durante las décadas de 1930 y 1940. Una de las hipótesis de trabajo es que la institución se construyó a partir de matrices de género, de clase y de militante católica que funcionaron, sin embargo, con limitaciones e incluso acompañaron las transformaciones del período. Asimismo, se presta especial atención a la actividad de la institución en relación a las transforma- ciones de la cultura de masas. Se sostiene que la AMAC tuvo una actitud rígida y al mismo tiempo flexible en este campo, en el marco de los procesos de modernización de la cultura que desafiaron la actualidad del catolicismo y su potencial para interpelar a los fieles.
La huerta de autoconsumo en la Sierra de Huelva: calidad, soberanía y apego alimentario
Authors: García Martín Miguel
Published: June 2023

El actual modelo de producción y consumo ha convertido los alimentos en un bien mercancía más del complejo engranaje económico capitalista y globalizado. En tal contexto, ser capaz de alimentarse al margen de este sistema —esto es, cultivar, cosechar y consumir la propia comida— se ha convertido en toda una aspiración social y en un alegato ideológico. En esta contribución se investiga el papel de las huertas de autoconsumo que hay repartidas por la Sierra de Huelva, analizando las diversas dimensiones que las componen más allá de su estricta función productiva. Por medio de encuestas, entrevistas y observaciones de campo se han obtenido resultados relevantes que ayudan a caracterizar estos sistemas agroalimentarios como espacios multifuncionales, marginales en lo espacial aunque paisajísticamente singulares en un territorio dominado por la dehesa. Se llega a la conclusión de que los hortelanos que habitan estos pequeños núcleos serranos le otorgan un significado especial a la huerta y su cosecha, no solo por la calidad de los alimentos que obtienen, sino también por el afecto, el valor simbólico y el bienestar emocional que les proporcionan.
Comparative Assessment of Canephron® N and Ciprofloxacin as Monotherapy of Acute Uncomplicated Cystitis in Women
Authors: М. І. Давідов  , Н. Є. Бунова
Published: June 2023

The objective: to compare the efficacy and safety of Canephron® N and ciprofloxacin as monotherapy in the management of mild forms of acute uncomplicated cystitis in women of working age.Materials and methods. A prospective, randomized study of Canephron® N and ciprofloxacin for treating mild forms of acute uncomplicated cystitis (ACSS score <10) comprising 160 women aged 18-55 years was conducted from 2015 to 2017. Group I consisted of 80 women, who received oral Canephron® N 2 tablets 3 times daily for 30 days. Group II included 80 women who took oral ciprofloxacin0.5 g twice daily for 3 days. The results were assessed using the ACSS scale, urinalysis by microscopy, bacteriological examination ofurine, etc. The outcomes were evaluated at 3, 6 and 30 days, and one year after the treatment initiation.Results. In group I, monotherapy with Canephron® N resulted in a marked improvement in symptoms, a decrease in the ACSS scores from 7.9 at baseline to 0.1 at day 30. The indicator of clinical efficacy (recovery) was 93.75%, bacteriological efficiency was 91.3%, relapse of cystitis within one year was observed in 5% of patients; no side effects were registered. In group II, the symptoms and bacteriuria decreased more rapidly in the early periods, but after 30 days the results of clinical and bacteriological efficacy did not differ from the group I (93.75 and 91.3%, respectively). Side effects and cystitis relapses were noted in 18.8% and 12.5% of patients, respectively.Conclusion. The findings of the study show that Canephron® N is an effective and safe alternative to treating mild forms (ACSS score <10) of acute uncomplicated cystitis in women, allowing the use of antibiotics to be reduced. In our opinion, patients with more severe forms of acute uncomplicated cystitis should be treated with traditional antibiotic therapy.
COVID-19 mimicked fetal hemolytic disease: a case report
Authors: Lakhno I.V.
Published: June 2023

The pandemic of COVID-19 changed the traditional approaches to the management of gestational complications. Today there is still a lack of information about the impact of COVID-19 on the pregnancy course, in particular, about its role in relation to Rh-conflict during pregnancy.The paper focused on a rare presentation of Rh-conflict pregnancy and COVID-19. 32 years old G3 P2 pregnant women with Rh-negative had a third pregnancy. The injection of anti-D immunoglobulin after the first abortion was not performed. The second pregnancy finished with a term delivery and the birth of a fetus with hemolytic disease. During the third pregnancy, the woman fell ill with COVID-19 in the 26th week. The bilateral pneumonia was diagnosed.The treatment included antibiotics, antiviral, antithrombotic, and anti-inflammatory drugs. No signs of fetal hemolytic disease were found via ultrasonography. But the abnormal level of anti-D antibodies – 1:1024 was detected. From the 28th weeks of pregnancy till the delivery the test for anti-D antibodies was constant – 1:4. The variables of utero-placental, fetal (blood flow velocity in a middle cerebral artery), and umbilical hemodynamics were normal during the third trimester. But fetal moderate hepato- and splenomegaly were found at 36 weeks of gestation. The patient delivered at 38 weeks of gestation a female newborn 3100 g, 52 cm with a 7→8 Apgar score. The laboratory investigation detected a hemoglobin value of 202.6 mg/dL in a child. The blood analysis showed total bilirubin of 44.2 mg/dL, direct bilirubin of 1.0 mg/dL, and a negative result on the direct Coombs test. The baby received phototherapy for 3 days. Total bilirubin was decreased (15.2 mg/dL). The newborn was discharged from a hospital with the mother on the fifth day.COVID-19 could change the placental permeability and increase the titer of anti-D antibodies. But it did not contribute to fetal and newborn hemolytic disease.
Hemoperitoneum as a result of bleeding from a vein lying on the capsule of subserous leiomyoma of uterus (Clinical case)
Authors: Bila V.V. , Kostenko O.Yu. , Slobodianik O.Ya. , Leush S.S. , Ter-Tumasova A.G.
Published: June 2023

Leiomyoma is a benign tumor of the uterus and it is considered to be the most sensitive tumor of the female genital organs. The tumor can have submucosal, intramural, and subserosal localizations, each of which has specific features of the course and complications. The article describes the clinical observation of a case of intra-abdominal bleeding, which was caused by the rupture of a vein lying on the capsule of a subserous uterine leiomyoma.Literature data about the leiomyoma frequency and its localization are presented in the article, as well as an explanation of the complexity of the true assessment of the frequency of this pathology, the peculiarities of a described case from a clinical and pathomorphological point of view. A review of the literature allowed to find 125 descriptions of clinical cases of bleeding from the vessel of the subserosal node during the last 100 years.The presented clinical case is interesting from the point of diagnosis. The picture of an “acute abdomen” by leiomyoma is most often associated with a blood circulation disorder of the node, and in this case it was caused by a rupture of a vessel due to twisting of the node and bleeding from the vessel. The patient with a history of subserous leiomyoma of the uterus was hospitalized with complaints of discomfort in the lower abdomen.During the objective examination, an enlarged uterus up to 16 weeks of pregnancy was diagnosed, and during ultrasound examination a leiomyoma node in the uterine fundus, which was twice larger than the uterus size itself, and up to 500 ml of blood in the abdominal cavity were found. During surgery, a subserous node in the uterus fundus with partial torsion was found, the source of bleeding was established – a vein on the posterior wall of the uterus. The patient was operated by conservative myomectomy, histological examination confirmed uterine leiomyoma, the patient was discharged in satisfactory condition.Recent systematic literature reviews have shown that myomectomy is a better surgical procedure compared to hysterectomy, as it reduces the prevalence of shock and blood loss in patients.
Новый потенциометрический сенсор для количественного определения ибупрофена
Authors: Кормош Жолт , Горбатюк Наталия , Кормош Наталия , Шевчук Николай , Люшук Катерина , Коцар Валентина , Бохан Юлия , Боркова Светлана
Published: June 2023

Разработан потенциометрический ибупрофен-чувствительный сенсор с пластифицированной поливинилхлоридной мембраной. Сенсор содержит ионный ассоциат ибупрофена с кристаллическим фиолетовым. Отклик линеен в пределах изменения концентрации ионов ибупрофена 9 · 10–5 – 1 · 10–1 М с крутизной электродной функции, характерной для однозарядного аниона — 56 ± 2 мВ/pC, минимальная концентрация определения составляет 4 · 10–5 М (pH 8 – 11). Данный сенсор может быть использован для обнаружения и количественного определения ибупрофена в лекарственных средствах (RSD = 0,29 – 4,23 %).
Перспективный стимулятор когнитивных функций на основе производного биспидина (OSPL-502)
Authors: Григорьев Владимир Викторович , Лавров Мстислав Игоревич , Палюлин Владимир Александрович , Гарибова Таисия Леоновна , Бачурин Сергей Олегович
Published: June 2023

Фармакологическое вещество на основе нового производного биспидина — 3,7-бис(1,3-бензодиоксол-5-илкарбонил)-1,5-диметил-3,7-диазабицикло[3.3.1]нонан-9-он (OSPL-502) обладает выраженным когнитивно-стимулирующим эффектом у крыс. Этот эффект выявлен на модели амнезии у крыс, вызванной хроническим введением скополамина (1,2 мг/кг, внутрь в течение 20 дней) в тесте «Условный рефлекс активного избегания». Выявлено достоверное улучшение памяти в диапазоне доз 0,25 – 0,5 мг/кг (на 47 %, p < 0,05), по сравнению с активным контролем (воздействие скополамина). Соединение OSPL-502 превосходило по активности мемантин (2 мг/кг) в этой же модели амнезии.
Влияние 4-(2-метил-6-этил-4-оксо-5-фенил-4H-пиримидин-1-ил)- бензсульфамида на параметры антиоксидантной системы головного мозга в условиях экспериментальной хронической травматической энцефалопатии у крыс
Authors: Потапова Анна Александровна , Мирошниченко Кирилл Александрович
Published: June 2023

При экспериментальной хронической травматической энцефалопатии у крыс отмечено развитие окислительного стресса в головном мозге: повышает содержание продуктов перекисного окисления липидов в среднем на 92,1 % (p < 0,05) и снижается активность ферментов антиоксидантной защитной системы: супероксиддисмутазы, глутатионпероксидазы, глутатионредуктазы — на 150,4, 167,7 и 320 % (p < 0,05) соответственно. Соединение 4-(2-метил-6-этил-4-оксо-5-фенил-4H-пиримидин-1-ил)-бензсульфамид (100 мг/кг внутрь 7 дней) вызывает снижение концентрации продуктов перекисного окисления на 116,8 % (p < 0,05), что сравнимо с действием гопантеновой кислоты (100 мг/кг внутрь, 7 дней), и увеличение активности супероксиддисмутазы на 113 % (p < 0,05), что превосходит эффекты всех препаратов сравнения. Под влиянием исследуемого соединения достоверно возрастала активность глутатионпероксидазы на 94,4 %, что сопоставимо с действием препарата сравнения — цитруллина малата (25 мг/кг внутрь, 7 дней), а наблюдаемое при этом повышение активности глутатионредуктазы на 185 % сопоставимо с действием гопантеновой кислоты.
Влияние производных хиназолинона на митохондриальную функцию клеток головного мозга крыс с фокальной церебральной ишемией
Authors: Поздняков Дмитрий Игоревич
Published: June 2023

Изучаемые производные хиназолинона в дозах 40 мг/кг и препарат сравнения этилметилгидроксипиридина сукцинат в дозе 100 мг/кг вводили крысам внутрь на протяжении 3 дней с момента моделирования ишемии. Установлено, что в условиях фокальной ишемии головного мозга у крыс в митохондриальной фракции мозговой ткани уменьшается активность цитратсинтазы, цитохром с-оксидазы и сукцинатдегидрогеназы на 73, 67 и 49 % (p < 0,05) соответственно, что сопровождалось увеличением концентрации митохондриального пероксида водорода в 2,8 раза и апоптоз-индуцирующего фактора — в 7,1 раза (p < 0,05), при угнетении аэробного и активации анаэробного дыхания на 31 % и в 4,3 раза (p < 0,05) соответственно. Применение этилметилгидроксипиридина сукцината приводило к повышению активности митохондриальных ферментов в среднем на 59 % (p < 0,05), уменьшению содержания митохондриального пероксида водорода и апоптоз-индуцирующего фактора на 40 и 26 % (p < 0,05), а также повышению аэробного дыхания на 34 % (p < 0,05), при снижении анаэробного дыхания на 50 % (p < 0,05). Вещества под шифрами РП-4 и РП-5 (2-[[2-(2-изопропил-6,7-диметокси-4-оксохиназолин-3-ил)ацетил]амино]уксусная кислота и 2-[[2-(2- пропил-6,7-диметокси-4-оксо-хиназолин-3-ил)ацетил]амино]уксусная кислота, соответственно) в митохондриальной фракции мозговой ткани повышали активность митохондриальных ферментов, аэробного обмена на 23,9 и 30,3 % (p < 0,05) при уменьшении анаэробного обмена на 32,4 и 24,5 % (p < 0,05), снижали концентрацию митохондриального пероксида водорода на 20,7 и 19,5 % (p < 0,05) и апоптоз-индуцирующего фактора в супернатанте мозговой ткани — на 23,4 и 21,1 % (p < 0,05).