bluuebunny/crossref_metadata_2025 huggingface dataset:
Radiology Performed Fluoroscopy-Guided Lumbar Punctures Decrease Volume of Diagnostic Study Interpretation – Impact on Resident Training and Potential Solutions
Authors: Richards Tyler John , Schmitt James Eric , Wolansky Leo J. , Nayate Ameya P.
Published: July 2021

Objectives:

Lumbar punctures performed in radiology departments have significantly increased over the last few decades and are typically performed in academic centers by radiology trainees using fluoroscopy guidance. Performing fluoroscopy-guided lumbar punctures (FGLPs) can often constitute a large portion of a trainee’s workday and the impact of performing FGLPs on the trainee’s clinical productivity (i.e. dictating reports on neuroradiology cross-sectional imaging) has not been studied. The purpose of the study was to evaluate the relationship between the number of FGLPs performed and cross-sectional neuroimaging studies dictated by residents during their neuroradiology rotation (NR).

Material and Methods:

The number of FGLPs and myelograms performed and neuroimaging studies dictated by radiology residents on our neuroradiology service from July 2008 to December 2017 were retrospectively reviewed. The relationship between the number of FGLPs performed and neuroimaging studies (CT and MRI) dictated per day by residents was examined.

Results:

Radiology residents (n = 84) performed 3437 FGLPs and myelograms and interpreted 33402 cross-sectional studies. Poisson regression demonstrated an exponential decrease in number of studies dictated daily with a rising number of FGLPs performed (P = 0.0001) and the following formula was derived: Number of expected studies dictated per day assuming no FGLPs × e-0.25 x number of FGLPs = adjusted expected studies dictated for the day.

Conclusion:

We quantified the impact performing FGLPs can have on the number of neuroimaging reports residents dictate on the NR. We described solutions to potentially decrease unnecessary FGLP referrals including establishing departmental guidelines for FGLP referrals and encouraging bedside lumbar punctures attempts before referral. We also emphasized equally distributing the FGLPs among trainees to mitigate procedural burden.
Haptic virtualisation of surfaces: feeling textiles on your phone
Authors: Braune Annerose , Martin Christopher , Le Tung
Published: July 2021

The haptic impression of textile surface properties has a decisive influence on its evaluation and ultimately on its acceptance and usability.  Many solutions are used to replicate a static contour or shape, e.g. to feel controls on common touch displays. In contrast, this project investigates whether it is possible to simulate the roughness or friction behaviour of a textile surface using a commercially available mobile device.
Tricuspid Annular Plane Systolic Excursion as a Potential Marker of Hospital Utilization in Patients with Sickle Cell Disease
Authors:   University of Illinois at Chicago, College of Medicine, Chicago, USA, HR Seyller , AP Harkins ,   University of Illinois at Chicago, College of Medicine, Chicago, USA, A Rodriguez ,   University of Illinois at Chicago, College of Medicine, Chicago, USA, S Mahrat ,   University of Illinois at Chicago, College of Medicine, Chicago, USA, D Gutierrez ,   Department of Emergency Medicine, University of Illinois at Chicago, Chicago, IL, USA, J Colla ,   Department of Emergency Medicine, University of Illinois at Chicago, Chicago, IL, USA, HT Khong ,   University of Illinois at Chicago, Internal Medicine-Pediatrics, Chicago, IL, USA
Published: July 2021

Objective: Pulmonary Artery Hypertension (PAH) is an independent risk factor for increased morbidity in Sickle Cell Disease (SCD) patients. Tricuspid Annular Plane Systolic Excursion (TAPSE) can be used as a surrogate measure for PAH. The objective of this study was to determine whether lower TAPSE values are associated with increased Emergency Department (ED) and hospital utilization. Methods: TAPSE measurements were retrospectively obtained from bedside echocardiograms from a convenience sample of 28 SCD patients presenting to the ED with SCD pain. TAPSE was considered abnormal if <24.9mm, one standard deviation below the mean TAPSE for SCD patients. Medical records were reviewed to determine ED visits and hospital overnight stays over a two-year period. A t-test analysis and Pearson’s correlation were used for each variable. Results: The initial sample included 28 SCD patient encounters. TAPSE measurements were abnormal in 5 patients and normal in 23 patients. The mean number of ED visits/year for the abnormal and normal TAPSE group were 23.00 and 16.87, respectively (p=0.57) with moderate negative linearity (p=0.03). The mean number of hospitalized days for abnormal and normal TAPSE groups was 108.8 and 59.6, respectively (p=0.10) with moderate negative linearity (p=0.07). Conclusion: Lower TAPSE values (<24.9mm) in SCD patients were associated with higher ED and hospital utilization. If findings are replicated in larger studies, TAPSE may serve as a marker of morbidity in SCD patients presenting to the ED.
SudoQ -- a quantum variant of the popular game
Authors: Nechita Ion , Pillet Jordi
Published: July 2021

(pp781-799) doi: https://doi.org/ Abstracts: We introduce SudoQ, a quantum version of the classical game Sudoku. Allowing the entries of the grid to be (non-commutative) projections instead of integers, the solution set of SudoQ puzzles can be much larger than in the classical (commutative) setting. We introduce and analyze a randomized algorithm for computing solutions of SudoQ puzzles. Finally, we state two important conjectures relating the quantum and the classical solutions of SudoQ puzzles, corroborated by analytical and numerical evidence.
VIVIR EN TIEMPOS CONVULSIONADOS. REFLEXIONES SOCIOCRÍTICAS PARA PROPUESTAS DE INTERVENCIÓN SOCIAL
Authors: Iturrieta Sandra
Published: July 2021

Existen múltiples razones por las cuales un grupo de personas se da a la tarea de escribir un libro. En nuestro caso, “Vivir en tiempos convulsionados: desde reflexiones sociocríticas hacia propuestas para la intervención social”, que es el primer libro producido por el Núcleo de Investigación Sobre las Profesiones en las Sociedades Contemporáneas, de la Pontificia Universidad Católica de Valparaíso, responde a un doble interés. Por una parte, en los tiempos políticamente agitados que corren en Chile y Latinoamérica, queremos ser partícipes de la construcción de las subjetividades con que enfrentaremos el entramado sociocultural y político futuro. En tal escenario nos interesa problematizar las encrucijadas, oportunidades, interespacios, desafíos, límites, y las fronteras o grietas de la intervención social, desde distintas miradas polidimensionales e interdisciplinarias. Por otro lado, con una escritura comprometida con pensamientos sociocríticos, queremos dar voz a las experiencias, logros y desvelos, que profesionales de intervención social directa, o cara a cara, nos han relatado a través de diversas instancias. Su coraje para desafiar la vida en tiempos convulsionados nos ha inspirado para ponernos como meta, en la escritura de cada uno de los capítulos, la elaboración de propuestas vinculadas a la intervención social y a la formación profesional en ciencias sociales, y en particular en Trabajo Social.
SEMIÓTICA JURÍDICA COMO PARTE DA SEMIÓTICA GERAL: INTERTEXTUALIDADES E INFLUÊNCIAS
Authors: Maia Vinícius Wagner De Sousa
Published: July 2021

Este trabalho parte da hipótese de que o direito pode ser investigado pela abordagem semiótica, mas para isso é preciso inicialmente compreender que existem diferentes teorias e modelos explicativos semióticos, o que é tratado no tópico 1.1 em sua dimensão conceitual. Adiante, no tópico 1.2, aprofunda-se a análise a partir dos desdobramentos teóricos de Saussure, Jakobson, Peirce e Greimas. No tópico 1.3 apresenta-se uma análise desenvolvida por Greimas e outros investigadores envolvendo A construção de objetos semióticos: análise semiótica de um discurso jurídico: a lei comercial sobre as sociedades e os grupos de sociedades. A conclusão confirma a hipótese.
DEMOCRACIA ILIBERAL E SOCIEDADE EM REDE: A era das redes sociais e seus impactos na democracia.
Authors: Pereira Filho Rainel Batista , Diógenes João Victor De Hollanda , De Goes Ricardo Tinoco
Published: July 2021

Este texto investiga, com base em recentes acontecimentos jurídicos e políticos, elementos causadores de uma crise na democracia representativa com base na diminuição do apoio popular e no abalo às suas instituições garantidoras, indagando-se, ademais, acerca de em que medida as redes sociais contribuíram para este quadro. Para tanto, utilizou-se revisão bibliográfica no âmbito nacional e alienígena, utilizando-se do método hipotético-dedutivo. Ao final, busca-se refletir sobre a importância da democracia, enquanto tutela das minorias e como as redes sociais vêm sendo utilizadas principalmente por um espectro do debate público para angariar apoio popular a uma pauta contra o liberalismo político.
Public understanding of climate change-related sea-level rise
Authors: Priestley Rebecca , Heine Zoë , Milfont Taciano L
Published: July 2021

Sea-level rise resulting from climate change is impacting coasts around the planet. There is strong scientific consensus about the amount of sea-level rise to 2050 (0.24–0.32 m) and a range of projections to 2100, which vary depending on the approach used and the mitigation measures taken to reduce carbon emissions. Despite this strong scientific consensus regarding the reality of climate change-related sea-level rise, and the associated need to engage publics in adaptation and mitigation efforts, there is a lack of empirical evidence regarding people’s understanding of the issue. Here we investigate public understanding of the amount, rate and causes of sea-level rise. Data from a representative sample of New Zealand adults showed a suprising tendency for the public to overestimate the scientifically plausible amount of sea-level rise by 2100 and to identify melting sea ice as its primary causal mechanism. These findings will be valuable for scientists communicating about sea-level rise, communicators seeking to engage publics on the issue of sea-level rise, and media reporting on sea-level rise.
Variation and extrema of human interpupillary distance
Authors: Dodgson Neil
Published: July 2021

No description supplied
Creases and boundary conditions for subdivision curves
Authors: Kosinka J , Sabin M , Dodgson Neil
Published: July 2021

Our goal is to find subdivision rules at creases in arbitrary degree subdivision for piece-wise polynomial curves, but without introducing new control points e.g. by knot insertion. Crease rules are well understood for low degree (cubic and lower) curves. We compare three main approaches: knot insertion, ghost points, and modifying subdivision rules. While knot insertion and ghost points work for arbitrary degrees for B-splines, these methods introduce unnecessary (ghost) control points. The situation is not so simple in modifying subdivision rules. Based on subdivision and subspace selection matrices, a novel approach to finding boundary and sharp subdivision rules that generalises to any degree is presented. Our approach leads to new higher-degree polynomial subdivision schemes with crease control without introducing new control points. © 2014 The Authors. Published by Elsevier Inc.
Example-based terrain synthesis with pit removal
Authors: Scott Joshua J , Dodgson Neil
Published: July 2021

No description supplied
Drenagem de tórax em pacientes com COVID-19
Authors: Reinaldo Luis Gustavo Cavalcante , Alencar Auriane de Sousa , Leite Camila Botelho Campelo , Silva Ilana de Meneses , Martins Tarso Buaiz Pereira , Lima Maria de Fátima de Brito Coutinho Nogueira , Cardoso Virgínia Portela
Published: July 2021

Objetivos: descrever a experiência e os resultados da equipe cirúrgica do Hospital Universitário da Universidade Federal do Piauí (HU UFPI) na realização de drenagem torácica na unidade de terapia intensiva (UTI) covid. Métodos:  estudo retrospectivo que se analisou os prontuários médicos dos pacientes submetidos à drenagem torácica no período de abril a agosto de 2020. Durante esse período, 13 pacientes com exames positivos para Covid 19 foram submetidos ao procedimento. Variáveis estudadas: idade, gênero, indicação da drenagem de tórax, uso ou não de ventilação mecânica, desfecho (alta da UTI ou óbito). A drenagem de tórax foi realizada sempre por um residente de cirurgia geral, sob orientação de um cirurgião geral. Resultados: idade média dos pacientes foi de 67.7 anos, sendo que 69.2% eram do sexo masculino. A indicação mais frequente foi pneumotórax espontâneo com 61.5% dos casos, pneumotórax secundário 15.38% e derrame pleural em 15.38%. Uso de ventilação mecânica em 84.6%. Melhoria do padrão respiratório e da expansibilidade pulmonar ocorreu em 61.5%. Não houve complicações e mortalidade relacionada ao procedimento. Tais pacientes tiveram como desfecho óbito em 76.9% e melhora clínica em 23.1% dos casos. Conclusão: concluímos que a drenagem de tórax, quando realizado com base em protocolos, é segura e altamente eficaz para o tratamento de complicações pulmonares do Covid-19, como pneumotórax e derrame pleural.
Preditores de endometriose em mulheres atendidas em um Hospital Universitário
Authors: Morais Ronisa Leal de , Rosal Marta Alves
Published: July 2021

INTRODUÇÃO: A endometriose afeta o bem-estar físico e mental da mulher, porém, sua etiopatogenia ainda não foi completamente explicada e engloba sintomas que também se apresentam em outras doenças, podendo ser subdiagnosticada. OBJETIVO: Avaliar os preditores de endometriose em mulheres atendidas em um hospital universitário. MÉTODO: Delineamento transversal controlado, desenvolvido no setor da saúde da mulher de um hospital universitário do nordeste do Brasil. A população do estudo compreendeu mulheres que realizaram histopatológico para investigação de endometriose. A amostra foi composta por 24 pacientes com diagnóstico de endometriose e 24 sem endometriose, totalizando 48 participantes. A amostragem foi censitária para o grupo de estudo e aleatória simples para o grupo de comparação. Foram coletados dados sociodemográficos, hábitos de vida, antecedentes gineco-obstétricos e características clínicas. Os preditores foram avaliados por meio do modelo de regressão de Poisson no software IBM® SPSS® 26.0. O estudo foi aprovado por Comitê de Ética. RESULTADOS: Quinze variáveis atenderam aos requisitos do modelo multivariado e oito apresentaram relação significativa com endometriose, confirmada por histopatológico. Mulheres na menacme (p=0,020), baixa escolariade (p=0,006), baixa paridade (p<0,001), tempo de amamentação inferior a 6 meses ou ausência de amamentação (p=0,007), aumento de 1 kg no peso ideal (p=0,004), presença de dor pélvica crônica (p=0,016) e a queixa de dor urinária cíclica (p=0,049) foram preditores da endometriose, enquanto a realização de laqueadura tubária apresentou-se como fator protetor (p=0,011). CONCLUSÃO: Foram identificados preditores socioeconômicos e clínicos para endometriose confirmada por meio de exame histopatológico. Os resultados fornecem respostas fidedignas, tendo em vista que foram baseados no padrão-ouro para diagnóstico da doença, dessa maneira, podem subsidiar a elaboração de protocolos de triagem ajudando a agilizar o diagnóstico da endometriose.
Mensagem do Superintendente
Authors: Nunes Paulo Márcio Sousa
Published: July 2021

É com muita satisfação que apresentamos o novo volume do Jornal de Ciências da Saúde do Hospital Universitário da Universidade Federal do Piauí (JCS HU-UFPI), lançado em formato digital em 2018, com periodicidade quadrimestral. Este periódico é um marco de importância para a comunidade acadêmica do HU-UFPI/EBSERH, assim como para todo o Piauí, tornando públicas as pesquisas desenvolvidas dentro e fora do hospital. Dessa forma, o JCS HU-UFPI atinge o objetivo de divulgação da produção acadêmica e aquisição de conhecimentos que possibilitam a construção de novas práticas, apoiadas em tecnologias já existentes e exercitando a implementação de novas práticas, atendendo critérios de qualidade, exigidos para tais periódicos. Destacamos, ainda, a importância singular das produções científicas multidisciplinares durante a pandemia de Covid-19, que acomete a humanidade desde 2020, o que iniciou uma corrida por descoberta de terapêuticas eficazes na prevenção, tratamento e reabilitação da doença. Parabenizo o corpo editorial do periódico e à Gerência de Ensino e Pesquisa do HU-UFPI por todos os esforços empreendidos em prol de ofertar à comunidade acadêmica a difusão de material científico de qualidade na área da saúde, com base nos preceitos éticos e humanistas.
Anais de Eventos
Authors:   Hospital Universitário da UFPI
Published: July 2021

Jornada Científica da Residência Médica da Universidade Federal do Piauí é um dos principais eventos científicos da UFPI. Nessa Jornada, os médicos que estão concluindo seus programas de residência apresentarão pesquisas científicas de excelente qualidade, que retratam a excelência do ensino e da pesquisa médica na UFPI. Neste evento estarão reunidos todos os médicos residentes, preceptores e supervisores dos diversos programas, compartilhando conhecimento médico e inovação em saúde. Convidamos todos a participarem da XII Jornada Científica da Residência Médica da UFPI e prestigiarem os novos profissionais especialistas oriundos da nossa Instituição. Agradecemos a colaboração de todos que estiveram e continuam envolvidos com as Residências Médicas da UFPI.
LIMITACIONES Y PRINCIPALES RETOS DE LA ORALIDAD CIVIL EN EL SISTEMA JUDICIAL PERUANO
Authors:   UNIVERSIDAD CATÓLICA DE SANTA MARÍA, AREQUIPA – PERÚ, RAMIREZ CUEVA GELBER , CHAVEZ SALINAS GERALDINE ,   UNIVERSIDAD CATÓLICA DE SANTA MARÍA, AREQUIPA – PERÚ
Published: July 2021

ABSTRACT: The article presented contains an analysis of the main challenges that the implementation of the Civil Oral Litigation model in the Peruvian Judicial System represents, through the identification of recurrent challenges previously identified through the 1993 Civil Procedure Code, as well as the description of some possible limitations of the Peruvian Judicial System; to conclude with recommendations and practical actions to be taken by magistrates, lawyers and law students, as well as politicians, legislators and academics in the area. Key words: Oral litigation, Civil Law, civil reform.
LA (IN)DEBIDA REGULACIÓN DE LA TUTELA CAUTELAR EN EL PROCESO DE AMPARO PERUANO
Authors:   UNIVERSIDAD CATÓLICA DE SANTA MARÍA, AREQUIPA – PERÚ, CAMARGO RIEGA ALBERTO VITTORIO , VALDIVIA CORZO MARIA GRACIA ,   UNIVERSIDAD CATÓLICA DE SANTA MARÍA, AREQUIPA – PERÚ
Published: July 2021

ABSTRACT: This article is about the study of the regulation of measures in the amparo process in Peru; A review of historical character is made. In addition, a doctrinal and jurisprudential analysis of the characteristic "inaudita altera pars" is carried out. Likewise, a study of this characteristic is carried out in relation to the nature of the amparo process against regional and local governments. Keywords: Interim measure, amparo, inaudita altera pars, process, constitutional
¿ES POSIBLE LA PROTECCIÓN INTERNACIONAL DE LOS DERECHOS DE LOS CONTRIBUYENTES?
Authors:   UNIVERSIDAD CATÓLICA DE SANTA MARÍA, AREQUIPA – PERÚ, VALDEZ VELAZCO SILDA
Published: July 2021

ABSTRACT: In the present investigation, we seek to describe and establish how two international organizations such as the Inter-American Court of Human Rights and the European Court of Human Rights, precisely responsable for the protection of the human rights of the citizens of their member states, have managed to concretize the protection of the rights of taxpayers despite their poor regulation in international treaties base on those that impart justice. Thus, some of the cases in which there has been a ruling on tax issues are analyzed, the facts, the rights protected and how this protection has finally been materialized in specific cases. Key words: Human Rights, taxpayers, American Convention on Human Rights, European Convention on Human Rights, taxation.
Multiple septic emboli and myocardial infarction due to vaso-invasive Rhizomucor pusillus infection in a hematologic patient
Authors:   1Department of Intensive Care, Radboud University Medical Centre Nijmegen, The Netherlands,   2Department of Pathology,Radboud University Medical Centre Nijmegen, The Netherlands,   3 Department of Cardiology, Radboud University Medical Centre Nijmegen, The Netherlands
Published: July 2021

We present a case of a 63-year-old hematologic patient with pulmonary vaso-invasive zygomycosis with Rhizomucor pusillus after a second stem cell transplantation (SCT) for myelodysplastic syndrome, complicated by multi organ failure, myocardial ischemia and infarction. Zygomycosis is common in immunocompromised patients, especially after hematopoietic stem cell transplantation (HSCT). Mucor species have devastating vaso-invasive properties causing hematogenic dissemination. Antemortem diagnosis may be difficult due to negative cultures. Despite adequate treatment outcome tends to be poor. Cardiac zygomycosis is rare. In our patient, the clinical course and imaging results of the myocardial infarction are most consistent with coronary plaque rupture possibly provoked by severe vaso-invasive pulmonary infection and multi-organ failure.
Theory of the Evolution of Nurse Practitioner Practice
Authors: Heale Roberta
Published: July 2021

Aim: To determine the nurse practitioner's perception of scope of practice and understanding of changes to practice over time.

Background: A great deal of research about nurse practitioners has been conducted related to such things as role clarity, transition, or preparedness to practice and job satisfaction. Conceptual models of nurse practitioner practice have been developed to highlight practice processes, interprofessional relationships and more. However, none of this literature addresses nurse practitioner's perception of scope of practice, the impact of their changing practice experiences and how the understanding of their practice changes over time.

Methods: This grounded theory study was undertaken in Ontario, Canada, with interviews of primary health care nurse practitioners which resulted in the Theory of the Evolution of Nurse Practitioner Practice.

Conclusion: Within this theory, scope of practice is defined as nurse practitioners working to their maximum potential.  There are both intrinsic and extrinsic elements which render maximum practice potential a fluid and changing state.
Emphasizing the Nurse Practitioner Role in Addressing Unique Challenges Associated with Benzodiazepine use among the Elderly
Authors: Fournier Jennifer Lynn , Gorham Robyn
Published: July 2021

Aim: The aim of this paper is to discuss the use of benzodiazepine medications among the elderly, and the role of a nurse practitioner within this patient population. 

Background: Benzodiazepines are well known to have a negative impact on the mobility of elderly patients and to contribute to increased falls. These medications also have an impact on elderly patients’ ability to perform activities of daily living and to drive. Nurse practitioners offer holistic care to elderly patients. This includes prescribing medications, monitoring therapy, deprescribing medications and identifying opportunities for safe alternatives to treat a variety of conditions.

Methods: This paper presents a narrative review focused on the effect of benzodiazepine medications on the elderly patient population, with an emphasis on the use of benzodiazepines in insomnia. 

Conclusions: Findings of this review confirm the known risks associated with the use of benzodiazepines in the elderly and that these medications should be carefully considered in ongoing management.  The conclusions of this review support the use of nurse practitioners in the enhancement of the healthcare of the elderly through the continuum of assessment, monitoring, deprescribing of benzodiazepine medications when appropriate, as well as opportunities to implement alternative treatments.
Transparência das Instituições Particulares de Solidariedade Social na Região Autónoma da Madeira
Authors: Bandeira Ana , Ornelas Tomásia , Meira Deolinda , Azevedo Graça
Published: July 2021

Por imposição legal, as Instituições Privadas de Solidariedade Social (IPSS) necessitam de reforçar as exigências da transparência relativamente às atividades que realizam e aos recursos que utilizam. As contas do exercício destas instituições obedecem ao regime da normalização contabilística para as Entidades do Setor Não Lucrativo, devendo ser publicadas obrigatoriamente no seu sítio institucional eletrónico até ao dia 31 de maio do ano seguinte a que dizem respeito (art.º 14.º-A do Decreto-Lei n.º 172-A/2014, de 14 de novembro). O objetivo principal deste trabalho é o de analisar qual o nível de transparência das IPSS na Região Autónoma da Madeira (RAM). Para o efeito realizou-se um estudo empírico, tendo como população-alvo oitenta e cinco entidades, registadas naquela região e com o estatuto de IPSS. Metodologicamente, conjugaram-se dois métodos de investigação, o método quantitativo e o método qualitativo para aferir o grau de transparência destas entidades na RAM. Os resultados mostraram que existem entidades que, mesmo tendo site, continuam a não publicar os seus relatórios de contas. É uma situação preocupante, uma vez que muitas das entidades não cumprem os requisitos legais impostos na última alteração dos seus Estatutos, com penalizações daí decorrentes, nomeadamente a suspensão dos apoios do Estado e a impossibilidade de celebrar acordos de cooperação.
O setor empresarial nas regiões ultraperiféricas portuguesas Uma década em perspetiva
Authors: Luís Sardinha , Áurea Sousa , Eduardo Leite , Paulo Fernandes
Published: July 2021

O objetivo do presente trabalho é aprofundar o conhecimento e descrever a evolução do setor empresarial na Regional Autónoma dos Açores (RAA) e na Região Autónoma da Madeira (RAM). De salientar que na União Europeia (UE) existem nove regiões ultraperiféricas (RUP), sendo a RAA e a RAM duas delas. As RUP apresentam diversas especificidades que limitam o seu desenvolvimento económico e social, mas a sua importância estratégica é significativa face à Zona Económica Exclusiva (ZEE), pelo que importa conhecer. Através de um estudo descritivo e recorrendo a dados secundários publicados pelo Serviço Regional de Estatística dos Açores, Direção Regional de Estatística da Madeira e Instituto Nacional de Estatística, foi possível verificar que na RAA e na RAM, entre 2008 e 2017, existiu inicialmente uma regressão no número de empresas e posteriormente uma recuperação até 2017. Contudo, na RAA o número total de empresas em 2017 ainda não iguala o de 2008. Acresce que em ambas as regiões os números totais de pequenas, médias e grandes empresas em 2017 ainda não perfazem os números de 2008. Quanto à forma jurídica, na RAA as empresas individuais apresentam uma diminuição da sua expressão, enquanto na RAM a tendência é inversa. Relativamente aos setores de atividade económica, ocorreram algumas variações ao longo deste período, designadamente, em ambas as regiões, o setor da construção, tem vindo a diminuir a sua expressão e o setor do alojamento, restauração e similares tem aumentado a sua expressão em relação ao global de empresas, evidenciando uma mudança de paradigma.
THE EFFECTS OF SHORT TERM AND LONG TERM NAAD YOGA MEDITATION TRAINING ON MINDFULNESS IN UNIVERSITY STUDENTS
Authors: Joshi Navdeep , Sahrawat Mamta , Singh Vikram
Published: July 2021

Introduction: Meditation has been practiced since times immemorial consciously or unconsciously by the people from different origins and the trend has caught more attention of the researchers worldwide due to popularity of yoga in the recent years.
Method: Internet-delivered online NAAD yoga meditation training for 6 weeks was being imparted to the university level participants (n = 67) and were assessed before, during and after treatment, and their compliance with the intervention they received was tracked online. In the randomized controlled trail (RCT) study, the treatments were received at a time, place, and computer of the participants’ choosing with the proviso that the training be completed live and online during each of 6 successive weeks (6 days a week with a 32 minutes session each day). The trait MAAS, a 15-item scale designed to assess individual differences in the frequency of mindful states over time questionnaire was being used as tool to assess (also known as trait) mindfulness amongst all the participants.
Results: Both a short term (3 weeks) long-term (6 weeks) NAAD yoga meditation programs elicited a statistically significant improvement on MAAS scores (p<.000).
Metal ion chelation and anti-glycation properties of polysaccharides of Phyllanthus amarus plant
Authors: Dinesha R  , Santhosh Kumar N  , Chikkanna D  , Vedamurthy Joshi
Published: July 2021

The study was conducted to investigate the in vitro anti-glycation activity of Phyllanthus amarus plant extract. The above plant has been used for centuries for its useful health benefits in variety of inflammatory diseases. In current study, antioxidant, metal chelating and ferric ion reducing and antiglycation property was studied for the polysaccharides isolated from Phyllanthus amarus plant extract. At 25 μg/mL sugar concentration and Vitamin C, gave 57 % and 65 % inhibition in hydroxyl radical scavenging assay and in Antiglycation assay the extract and vitamin C showed 65% and 87% respectively. It also had metal ion chelating (PAPE 74%, Ascorbic acid 88%) and ferric ion reducing activity showed by PAPE IS about 68% when compared to standard metal ion chelator EDTA 90%. It inhibited fructosamine formation by 52% after 3 days of incubation. The above studies gave an opinion that the inhibition of glycation exhibited by extract was due to its free radical scavenging property but also due to the modification in the amino or carbonyl groups resulted in the inhibition of fructosamine formation. The polysaccharides of the extract may be donating the hydrogen atom to the free radical, and exhibiting the antioxidant activity. So polysaccharide isolated from Phyllanthus amarus plant may use in preventing many free radicals induced diseases and also in delaying or preventing complications of diabetes.
Leucas zeylanica is a Bangladeshi plant with significant medicinal prospect: A review
Authors: Md. Islam Molla  , Sabiha Parvin Ela
Published: July 2021

Leucas zeylanica is one of the most precious gifts of nature to the entire civilization. It offers folkloric system a dependable option to heal numerous diseases like- burning urination, toothaches, common skin diseases, gout, inflammatory conditions, rheumatic diseases, abdominal pain, worms, anorexia, colic, flatulence, etc. Many of these ancient practices have got their scientific resemblances like- using as an agent for treating common pains, oxidative stresses, microbial infections, sleep disorders, inflammations, gout associated pains, thrombosis and sunlight related skin damages. Some researchers also isolated a huge bunch of vital phytochemicals like- torosaﬂavone A, drymariatin C, daidzein, luteolin 3′,4′-dimethyl ether, apigenin, tricin, chrysoeriol, linarigenin, β-sitosterol, stigmasterol, hexadecanoic acid, octadecanoic acid, 9,12,15- octadecatrienoic acid, farnesene, β-caryophyllene, caryophyllene oxide, phytol, β-cubebene, α-selinene, α-tocopherol etc. from different crude extracts of Leucas zeylanica. Making proper correlation between these phytoconstituents with the general utilizations of this plant will assist scientists to develop auspicious lead compounds. This review covers a summary of ethnomedicinal, phytochemical and biological studies of several crude preparations of Leucas zeylanica.
Influence of social entrepreneurs on community development in Enugu west senatorial district of Enugu state, Nigeria
Authors: Nweke Prince Onyemaechi  , Micheal Temitope Elesho  , Imo Onyeodiri Charity  , Matthias U Agboeze  , Igwe Ngozi Justina  , Eze Georgina Chinagorom  , Okengwu Mary Chinyere  , Nwankwo Benedict Chimezie
Published: July 2021

Social entrepreneurship is not a new-fangled observable fact in Nigeria. Though the practice has constantly existed, for countless reasons, the concept is gaining reputation in current years. Although the focus has been on business entrepreneurship as a tool for economic development, the light is now on social entrepreneurship, which entails attempting to serious social issues for sustainable community development. Community development efforts have met with diverse challenges that hamper sustainability of the society. The appearance of social entrepreneurship as a cross move towards positive force for transforming communities put forwards the prospects of dealing with the key challenges of lack of support by government, deficiency of financial assistant, changing environment, out of pocket work, domination by wealthy founders and philanthropists, lack of skilled manpower, poverty, unemployment, illiteracy, climate changes, health care challenges, insecurity and other social and economic issues. This paper throws light on who social entrepreneurs are what they do and the role they play in achieving sustainable community development. Using a conceptual framework defined social entrepreneurs, characteristics, principles and role of social entrepreneurs towards community development process. The paper concludes with suggestive principles that could provide an enhanced insight on the role of social entrepreneurs in community development. To enhance their impact, social entrepreneurs should involve beneficiaries trapped within socio-economic problems in the process of community development.
Strategies for coping with frontier technologies and innovations in Africa
Authors: Felix Chukwuma Aguboshim  , Ifeyinwa Nkemdilim Obiokafor  , Irene Nkechi Onwuka­
Published: July 2021

Recent advancements in Frontier Technologies and Innovations (FTI), including artificial intelligence, robotics, and biotechnology have shown significant and tremendous potentials for sustainable development globally. Despite this, Africa appears to be unprepared to equitably use or adopt these technological innovations. Evidence has shown that the ongoing global growth in FTI negatively impacts Africa with multifaceted inequalities ranging from poor global class, persistent poverty, disparities in income-earning opportunities, internet usage, pay gap, poor standards of education and health, etc., resulting majorly from poor adoption of technological innovations and favorable Information and Communication Technology (ICT) policies, culture, ethics, and values. Significant digital divides were evident between the technologically advanced countries and backward countries such as Africa during the COVID-19 pandemic because technological innovations have become critical tools for addressing the spread of the disease. This study highlights the strategy for coping with FTI for sustainable development in Africa. The Unified Theory of Acceptance and Use of Technology (UTAUT) was adopted as the study conceptual framework. UTAUT model claims that users' acceptance behavior toward technology is determined by users' decision to use technology and the perceived benefits thereof. The researchers explored a narrative review, analysis, and synthesis of vast works of literature that revealed significant information on strategies for coping with FTI in Africa. The researchers also conjointly extracted peer-reviewed articles among the last five years from electronic databases, engaging some keywords like "Frontier Technologies and Innovations in Africa' 'Coping with Frontier Technologies and Innovations' leveraging resources of Africa via Technology and Innovation", etc. Results show that global progress was associated with sharper inequality between countries, with widening disparities in FTI adoption, literacy level, and access to products, social services such as ICT infrastructure, electrification, education, and health. Results also show that literacy empowerment in Africa especially among women, on technology adoption, policies, culture, ethics, and values may advance sustainable goals, leverage their literacy abilities for FTI adoption, and close widening gaps and inequalities in global FTI.
Ameliorative effect of sodium carbonate on phytotoxicity of palm oil mill effluent
Authors: Nicholas Chinedu Ewelike  , Jude N Ogbulie  , Justina C Orji  , Ifechi Adieze  , Adanma Ukaoma  , Vincent Ezechukwu Ogwudire
Published: July 2021

This study aims to evaluate the impact of palm oil mill effluent treated with sodium carbonate on the growth of maize. The experiment consisted of eight treatments of concentrations of palm oil mill effluent viz 1.0%, 2.0%, 3.0%, 4.0%, 5.0%, 6.0%, 7.0% and 8.0%. The treatment was carried out on potted maize plants with six replications. Four kilograms of soil was weighed into each pot. Six pots were labelled as control with untreated palm oil mill effluent added to them. Eight other groups consisting of six pots each were treated with 1.0%, 2.0%, 3.0%, 4.0%, 5.0%, 6.0%, 7.0% and 8.0% concentrations of the effluent. The maize seeds were planted one in each pot to avoid overcrowding. The pots were transferred to greenhouse and moistened daily with the effluent. The growth rate, plant height and leaf length of the maize plants were thereafter determined. The 8.0% concentration of sodium carbonate in the effluent had the highest expected effect on the parameters whereas the control gave the lowest expected effect. The effects increased as the concentration of sodium carbonate in the effluent increased, indicating that increased concentration of sodium carbonate recorded significant increase in growth rate, height and leaf length of maize. The analysis of variance for the obtained data showed that the effects of the different concentrations were significantly different. This study provides an alternative and cost effective method of ameliorating the toxicity of palm oil mill effluent to plants.
Pengaruh Hedonic Shopping Motivation, Shopping Lifestyle Dan Visual Merchandising Terhadap Impulse Buying (Pada Produk Fashion Mahasiswa Universitas Muhammadiyah Purwokerto)
Authors: Hidiani Agnes , Rahayu Tri Septin Muji
Published: July 2021

Penelitian ini bertujuan untuk mengetahui pengaruh Hedonic Shopping Motivation, Shopping Lifestyle dan Visual Merchandising Terhadap Impulse Buying. Penelitian ini menggunakan metode kuantitatif. Populasi dalam penelitian ini adalah Mahasiswa Universitas Muhammadiyah Purwokerto.Teknik pengambilan sampel menggunakan purposive sampling. Sampel pada penelitian ini adalah sebesar 110 responden. Alat analisis yang digunakan dalam penelitian ini adalah regresi berganda. Hasil dari penelitian ini menunjukkan bahwa variabel Hedonic Shopping Motivation, Shopping Lifestyle, dan Visual Merchandising secara parsial dan simultan berpengaruh positif dan signifikan terhadap Impulse Buying.
Vaccine Design, Adaptation, and Cloning Design for Multiple Epitope-Based Vaccine Derived From SARS-CoV-2 Surface Glycoprotein (S), Membrane Protein (M) and Envelope Protein (E): In silico approach
Authors: Habib Peter T.
Published: July 2021

Introduction: The SARS Coronavirus-2 (SARS-CoV-2) pandemic has become a global epidemic that has increased the scientific community's concern about developing and finding a counteraction against this lethal virus. So far, hundreds of thousands of people have been infected by the pandemic due to contamination and spread. This research was therefore carried out to develop potential epitope-based vaccines against the SARS-CoV-2 virus using reverse vaccinology and immunoinformatics approaches.Material and Methods: The material of SARS-COV2 Surface Glycoprotein (S), Membrane Protein (M), and Envelope Protein (E) were downloaded from the NCBI protein database. Each protein has undergone epitopes prediction for MHC class I epitopes, MHC class II epitopes, and Antibody of B-cell epitopes. Selected epitopes according to their antigenicity score was tested for allergenicity and toxicity. Finally, filtered epitopes were used in vaccine construction. Vaccines were constructed, docked against Toll-like receptor 3, and undergone Molecular Dynamic simulation. The vaccine with the best scores, subjected to immune stimulation and cloning design.Results: Three vaccines were constructed, COVac-1, COVac-2, and COVac-3. Each vaccine was submitted into a deep investigation. The molecular dynamic simulation determines the stability and physical movement of protein atoms and molecules. After Molecular dynamics simulation, COVac-1 was having the best scores. COVac-1 was then subjected to immune simulation analysis to insure the stimulation of innate and adaptive immunity. After passing the immune simulation, COVac-1 was integrated into E.coli pET-30b plasmid using in silico cloning design.Conclusion:Viral pandemics are threatened to face humanity today. The best scenario to fight against any pandemic is utilizing the full power of computational biology, especially immune-informatics, to design and discover in silico new vaccines or molecules that may stimulate the immune system against the invader pathogens or inhibit the pathogen life cycle.
Evaluation of the effect of informing patients through text messaging on antibiotic prescription by physicians in outpatient setting: a study protocol
Authors: Vakili Arki Hassan , Nabovati Ehsan , Saberi Mohammad Reza , Eslami Pourya , Taherzadeh Zhila , Eslami Saeid
Published: July 2021

Introduction: Irrational prescription of antibiotics has become a major global concern, and not only does it have health-related consequences, but it also affects countries’ overall economy. Based on reports and studies, antibiotics are prescribed in approximately 50% of prescriptions in Iran which can demand by patients as a major cause. It is anticipated that increasing the awareness and understanding of both physicians and patients, regarding the antibiotic use and resistance, could play an important role in the rational prescription of antibiotic medications. In this study, we will examine the effect of informing patients via text message right before their appointment on the proportion of prescribed antibiotic medications.Material and Methods: In this study, a randomized control trial (RCT) will be conducted. The setting in which the study will be carry out, consists of 64 physicians (29 general physician and 35 specialist). Unit of randomization will be physicians based on the proportion of their prescriptions that include antibiotic medications (PIA). The first arm of the study is the intervention group, which consists of the patients receiving three text messages in the clinic’s waiting rooms. The second arm is the control group, and consists of the patients who won’t be receiving any text messages. The content of the text messages focuses on the consequences of self-medication with antibiotics, the fact that the use of antibiotics is not an option for curing viral diseases including cold, and it also asks the patients not to demand antibiotics by trusting their physicians.Results: The main variable that will be measured is the proportion of prescriptions that include antibiotic medications.Conclusion: This trial will be the first one to evaluate the patients’ role in the proportion of prescriptions that include antibiotic medications. It is hypothesized that patients’ demand for antibiotic medication is one of the main causes of irrational antibiotic prescription by physicians.
Designing an Intelligent System for Diagnosing Type of Sleep Apnea and Determining Its Severity
Authors: Kohzadi Zeinab , Safdari Reza , Sadeghniiat Haghighi Khosro
Published: July 2021

Introduction: Sleep apnea syndrome can be considered as one of the most serious risk factors of sleep disorder. Due to the lack of information about this disease, many causes of unexpected deaths have been identified. With increasing the number of patients with this disease around the world, many patients suffer apnea complications.  Most of them are not treated because of the complex and costly and time-consuming polysomnography (PSG) diagnostic procedure.Material and Methods: This descriptive-analytical study was performed on 50 patients referred to sleep clinic of Imam Khomeini Hospital in Tehran,  Attempts to design, and develop a system for detection of sleep apnea and its severity using ECG signals, RR intervals and airflow. The random forest algorithm and MATLAB2016 were used in the design of the system that the algorithm inputs are extracted 8 features nonlinear in time-frequency domain from airflow and ECG signals and 10 nonlinear features of RR intervals.Results: The accuracy for normal, obstructive, central and mixed apnea was obtained at 95.3%, 97.92%, 99.60%, and 97.29%, respectively, and the accuracy For detection of normal, mild, moderate and severe apnea was obtained 96%, 94%, 94%, 96% respectively. According to the results, the proposed system can correctly classify the types of sleep apnea and its severity.Conclusion: The proposed system, which has high performance capability in addition to increasing the physician speed and accuracy in the diagnosis of apnea can be used in home systems and the areas where healthcare facilities are not sufficient.
Bactria in the Greek literature of the Classical epoch
Authors:   federal state budget educational institution of higher education «Saint Petersburg State University of Culture», Popov Artem A.
Published: July 2021

The article is dedicated to the appearance and the development of the Greeks’ knowledge about Bactria in the literature of the Classical epoch (V–IV centuries BC). Herodotus, Ctesias, Xenophon give us the most important information about Bactria. Ctesias’ «The Persian History» as the most significant work studying Ancient Bactria does not remain. The works by Diodorus of Sicily and Patriarch Photius are the main research on Ctesias’ work. Much more before the Eastern Campaign of Alexander, the Hellenes had the information about Bactria geography, its population, military forces and economic potential, the largest cities and their role in the Achaemenid Empire. Such information competently allowed to assess the perspectives during Alexander’s conquering of the Bactrian territories, for example, the strategic location of Bactria in his wide Empire. Beginning from Herodotus, some classical authors have formed the critical view about the Asiatic statehood. On the other side Ctesias promoted the compromise ideas, directing to cooperation with the «barbarian» East. In the same time Bactria and Bactrians became the background to advance all these ideologies.