bluuebunny/crossref_metadata_2025 huggingface dataset:
Dominios de competencias básicas para la inclusión del enfoque
Authors: Felipe Antonio E. , Chiapparrone María Laura , Caselli Andrea
Published: November 2023

Una amplia diversidad de organizaciones a nivel internacional se ha abocado a identificar los conocimientos, las capacidades, las habilidades y las actitudes que puedan considerarse fundamentales para que las personas contribuyan con éxito a los esfuerzos que requiere mirar nuestro planeta desde el enfoque de Una Salud. Este enfoque integrado, interdisciplinario, multisectorial y preventivo para proteger la salud humana, animal y ambiental lleva a considerar el desarrollo de competencias para la construcción de una identidad profesional integral. El objetivo de este trabajo es efectuar una revisión de las propuestas de competencias con enfoque Una Salud en el campo de la educación veterinaria. Los resultados obtenidos indican un consenso internacional en torno a dominios básicos o centrales de competencias Una Salud, denominados: Gestión, comunicación e informática, valores y ética, cultura, creencias y género, liderazgo, trabajo en equipo, colaboración y asociación, responsabilidad, pensamiento sistémico, políticas, promoción e investigación. Los países africanos incorporan género cultura y creencias, y los dominios: política y promoción e investigación. Para los dominios se proponen subdominios y ejemplos. Tanto las competencias como los atributos personales promovidos por el enfoque Una Salud, orientan la construcción integral de la identidad profesional.
Introducción a una semiótica de la distinción. Oposición, marcación y definición conceptual en la teoría de la cultura
Authors: Ibero Álvaro
Published: November 2023

En este texto se propone una aproximación a los mecanismos de producción de significación conceptual en el lenguaje y, por extensión, en las diciplinas que participan de la teoría de la cultura. A partir de los postulados de la Lingüística Estructural, se establece una introducción semiótica a la distinción, entendida como el sistema de correlación entre dos conceptos disyuntiva y exclusivamente opuestos, por el cual es posible producir —por oposición a lo conocido—significación para entidades extrañas. Se sostiene aquí que, lejos de tratarse de un «universal del lenguaje», este binarismo semiótico es propio de un sujeto sociohistórico particular, como resultado del ejercicio meta–reflexivo en el que participa el inconsciente individual. Finalmente, se sugiere que es a través de este proceso cómo los elementos de la alteridad de la cultura son construidos y conceptualizados por la Modernidad.
Una experiencia de implementación de la oralidad sincrónica en la evaluación de asignaturas de matemática en carreras de ingeniería
Authors: Garelik Mario Darío , Acosta María Florencia , Demarchi Analía Raquel
Published: November 2023

El trabajo se enmarca en un proyecto CAI+D 2020 que analiza el uso de distintos recursos lingüísticos, entre ellos la oralidad, en los procesos de enseñanza y aprendizaje en años iniciales de las carreras de ingeniería. La situación de salud que a nivel mundial se originó a inicios del año 2020 precipitó por completo la irrupción de la virtualidad en las prácticas de enseñanza. En este marco, la inexorable incorporación de tecnologías a la educación cobró protagonismo en los procesos de enseñanza y aprendizaje en general y, en particular, en la evaluación en la universidad. De manera específica, el presente trabajo describe la implementación de instancias orales sincrónicas en las evaluaciones finales de asignaturas de matemática de primer y segundo año de las carreras de ingeniería de la Facultad de Ingeniería y Ciencias Hídricas de la Universidad Nacional del Litoral y las implicancias de las mismas tanto en la enseñanza como en el aprendizaje. A partir del análisis cualitativo de los resultados de la experiencia, se evidencian tanto las potencialidades como los aspectos a mejorar de esta particular metodología de evaluación en la disciplina.
A Multistage High Capacity Reversible Data Hiding Technique Without Overhead Communication
Authors: Kumar Sanjay , Walia Gurjit Singh , Gupta Anjana
Published: November 2023

Reversible Data Hiding(RDH) has been extensively investigated, recently, due to its numerous applications in the field of defence, medical, law enforcement and image authentication. However, most of RDH techniques suffer from low secret data hiding capacity and communication overhead. For this, multistage high-capacity reversible data hiding technique without overhead is proposed in this manuscript. Proposed reversible data hiding approach exploits histogram peaks for embedding the secret data along with overhead bits both in plain and encrypted domain. First, marked image is obtained by embedding secret data in the plain domain which is further processed using affine cipher maintaining correlation among the pixels. In second stage, overhead bits are embedded in the encrypted marked image. High embedding capacity is achieved through exploiting histogram peak for embedding multiple bits of secret data. Proposed approach is experimentally validated on different datasets and results are compared with the state-of-the-art techniques over different images.
Feasibility Study of Lithium Ion Batteries for Torpedo Applications
Authors: Ragit Sumeet Sunilrao , Singh Karandeep , Srinivas M.
Published: November 2023

A comprehensive study on the feasibility of Lithium (Li)-ion battery technology for Light Weight Torpedoes (LWT) and Heavy Weight Torpedoes (HWT) applications are reported in this article. The global scenario of Li-ion battery technology for torpedo applications and current Indigenous Li-ion battery developments in India are studied. Configuration study of Li-ion battery for LWT and HWT with commercial cells was carried out and it is found feasible to partially meet the required power for LWT and HWT applications. A comparison of the cost per cycle of Li-ion battery versus AgO-Zn battery indicates that Li-ion batteries work out to be cheaper beyond 100 cycles of use and by an order of magnitude cheaper on average. The detailed survey on Indigenous developments reveals that cell-level development is predominant in public sector agencies, whereas the private sector is mostly focussed on the assembly of imported cells and BMS.
Nomographs for Polymeric Material Selection for Environmental Conscious Design of Industrial Products
Authors: Pandey Vidya Shanker , Agrawal Anil Kumar , Dubey Ashish
Published: November 2023

Environmentally-conscious product design using Life Cycle Assessment (LCA) deserves the utmost attention to save and sustain our planet’s lives, flora and fauna. The choice of materials during the design stage needs to address environmental concerns from their sourcing to production and ultimately going up to the disposal stage. A good majority of industrial products are still not designed, focusing the environmental concerns. The inclusion and practice of the LCA approach during product designing are in a nascent stage not only in India but even over the rest of the world. Nowadays, polymers share a major chunk of the volume of goods produced worldwide and thus have a significant effect on the environment. The available design books or nomographs guide the selection of materials considering several criteria but not considering the related environmental issues. This paper attempts to bridge this gap only for the selection of polymeric materials by providing some easily interpretable and visually ready reckoners in the form of 3-D nomographs. These 3-D nomographs, graphical representations developed using the Solidworks software, echo the material’s Environmental Impact (EI) potential on an axis with some two material properties (e.g., tensile strength and density) on the other two axes. 3-D nomographs are suitably transformed into 2-D nomographs without the loss of any information. EIs on these nomographs were computed using SimaPro software. The potential EI of any product and the overall environmental burden due to them can be significantly reduced, and more so when they are mass-produced, by selecting the right materials using these nomographs. Such an approach will help in fulfilling long-term sustainable development goals of society and the globe.
A strategy to recover a poor-quality ligase product
Authors: Prete Sonia Del , Gogliettino Marta , Palmieri Gianna , Cocca Ennio
Published: November 2023

Over the last decades, PCR and molecular cloning have profoundly impacted various biological areas, from basic to pharmaceutical sciences. Presented in this study is a simple and step-by-step protocol that uses PCR to recover a poor-quality ligase product. In fact, a classic step that can be problematic in typical recombinant DNA manipulations can be the recovery of a product from a T4 DNA ligase reaction between two or more suitably prepared DNA fragments (sticky ends, blunt ends, TA cloning, etc.). This reaction can result in poor yields of the ligation product, due to various causes, mainly the preparation of the DNA fragments, and the poor yield can severely invalidate all subsequent steps. To overcome this problem, we designed a pair of PCR primers to amplify the entire ligase product into satisfactory amount. Of course, high-fidelity DNA polymerase must be used to obtain a faithful copy of the DNA of interest. The fragment thus amplified can then be inserted into a suitable vector and propagated by bacterial transformation.We applied this procedure to modify a synthetic gene by adding a His-Tag to its 5’ end, and to insert this new construct into an expression cassette. This last step was achieved by employing a PCR cloning system. In our practical example, comprehensive PCR-based protocol with important tips were introduced. This methodological paper can serve as a roadmap for biologists who want to quickly/fully exploit the potential of the PCR-cloning to get desired constructs.
SOFTWARE-ALGORITHMIC COMPLEX OF FORECASTING THE DYNAMICS OF ARCTIC LAKES IN RUSSIA BASED ON SATELLITE IMAGES AND ENTROPY-RANDOMIZED APPROACH
Authors:   Ugra Research Institute of Information Technologies, Khanty-Mansiysk, Russia, Sokol E.S. , Togachev A.A. ,   Ugra Research Institute of Information Technologies, Khanty-Mansiysk, Russia, Popkov A.Yu. ,   Federal Research Center Computer Science and Control of the Russian Academy of Sciences, Moscow, Russia, Dubnov Yu.A. ,   Federal Research Center Computer Science and Control of the Russian Academy of Sciences, Moscow, Russia; National Research University Higher School of Economics, Moscow, Russia, Polishchuk V.Yu. ,   Institute of Monitoring of Climatic and Ecological Systems of the Siberian Branch of the Russian Academy of Sciences, Tomsk, Russia, Popkov Yu.S. ,   Federal Research Center Computer Science and Control of the Russian Academy of Sciences, Moscow, Russia; V.A. Trapeznikov Institute of Control Sciences of Russian Academy of Sciences, Moscow, Russia, Melnikov A.V. ,   Ugra Research Institute of Information Technologies, Khanty-Mansiysk, Russia, Polishchuk Yu.M. ,   Ugra Research Institute of Information Technologies, Khanty-Mansiysk, Russia
Published: November 2023

The article is devoted to the problem of predicting the evolution of thermokarst lakes in permafrost zones as intensive sources of natural emissions of greenhouse gases into the atmosphere in the Arctic territories. Goal of the work. The purpose of the work was to consider the issues of creating a software-algorithmic complex for predicting the spatio-temporal dynamics of lakes in the Russian Arctic based on methods and algorithms of randomized machine learning. Materials and methods. For forecasting, time series of satellite measurements of the areas of thermokarst lakes in the Arctic zone of Russia and data on the average annual temperature and annual precipitation obtained on the basis of the ERA-5, ERA-Interim, etc. reanalysis systems are used for forecasting. Methods of entropy-randomized dynamics modeling are used fields of thermokarst lakes, allowing to predict changes in the areas of lakes in the Arctic zone. For the software implementation of a complex for predicting the evolution of the area of thermokarst lakes, modern geographic information systems are used. Results. The architecture of the software-algorithmic complex has been developed, based on the use of entropy-randomized modeling algorithms. The software-algorithmic forecasting complex makes it possible to train and test the model based on available historical data on the dynamics of the area of thermokarst lakes and climate changes in the Russian Arctic. Conclusion. The implementation of a software package based on the NextGIS Web geographic information system allows you to include forecasting applications in Python. The developed software package can be used in assessing and forecasting the dynamics of greenhouse gas emissions from lakes, which influence changes in air temperature in the northern regions.
THE REVENUE FORECASTING MODEL OF FAST-GROWING ORGANIZATION
Authors:   V.A. Trapeznikov Institute of Control Sciences of Russian Academy of Sciences, Moscow, Russia, Dranko O.I. , Taroyan K.K. ,   Moscow Institute of Physics and Technology (National Research University), Moscow, Russia
Published: November 2023

We consider a revenue forecasting model for fast-growing organizations. We use the logistic curve for approximation of the growth curve. The purpose of the work is to predict the development of fast-growing organizations using the logistic curve function. Materials and methods. A set of system dynamics simulation models is used to predict the indicators of organizations. A particular case of approximating the revenue forecast is the logistic curve as a variant of the sigmoid. The information basis of the study was the open data of the Federal State Statistics Service (Rosstat), the State Information Resource of accounting (financial) statements of the Federal Tax Service. The least squares method was used to identify the parameters. Results. We identified more than 1200 fast-growing organizations of all industries with revenue of more than 1000 million rubles. The criterion for identifying fast-growing organizations is a compound annual growth rate of revenue of more than 50% per year. According to the actual data, the following parameters of the logistics curve were identified: growth potential, growth rate, and inflection point. The example of a fast-growing food delivery company, “SberMarket” is considered in more detail. According to the model forecast, the marginal value of the logistics revenue curve will be about 700 billion rubles. Conclusion. A study of fast-growing organizations in Russia has been conducted. The logistics curve model is applied to fast-growing companies. The approximation of the company’s growth by the logistics curve allowed us to assess of the growth of a sample of organizations. The growth assessment of “SberMarket” shows that the organization could become one of the dominant participants in the retail market with the current forecasting parameters.
APPLICATION OF MULTIPLE LINEAR REGRESSION MODEL FOR POTASH PRICES SHORT-TERM FORECASTING
Authors:   Perm National Research Polytechnic University, Berezniki Branch, Berezniki, Russia, Kopoteva A.V. , Zatonskiy A.V. ,   Perm National Research Polytechnic University, Berezniki Branch, Berezniki, Russia
Published: November 2023

The modern economy instability due to global and regional conflicts and contradictions leads to significant fluctuations in commodity markets. The demand and prices unpredictability leads to the raw materials in-dustries risks increase and limits their successful functioning and development. The purpose of the study. In this paper, we made an attempt of a multiple linear regression model application to obtain a forecast price of potash products acceptable quality. Despite the wide application and simplicity of construction and interpretation, the forecasting properties of such models are usually unsatisfactory. Nevertheless, an adequate selection of factors and the sample size used to estimate unknown parameters of the model, al-lows to achieve an acceptable forecasting quality. Materials and methods. In the issue the evaluation of the multiple linear regression model unknown parameters is performed on the basis of United States of America Geological Survey data. The sample contains information about the American potash market in the period from 1900 to 2020. The quality of forecasting is tested using the post-forecast method for years 2019 and 2020. The model built using the entire dataset gives an unsatisfactory relative prediction error. To reduce its value, a search of the sample volumes of data used for model parameters estimation was per-formed, and the one with the minimal forecast error was selected as optimal. The calculations were per-formed using MS Excel and Jupyter Notebook 6.1.4 environment for Python 3.8.5. Results. The conducted research allowed us to determine that in order to minimize the US domestic market potash products price relative error, it is necessary to use from 9 to 13 years time intervals for modeling. By doing that it is possi-ble to improve the 118-year time interval forecast for 2019 year by 23.9%, and a similar forecast for 2020 by 83.70%. Conclusion. Based on the results of the work done, it can be stated that the multiple linear re-gression model can be successfully used for short-term forecasting of the potash products price, and by an adequate modeling interval length choice it is possible to achieve acceptable forecasting quality.
Management of Artistic Practice Pedagogies of Interdisciplinary Art Students With Critical Analysis Learning Method
Authors: YAĞMUR Önder
Published: November 2023

This study aims to ensure that graduate students from plastic arts disciplines (sculpture, graphics, painting, ceramics) can develop their critical analysis skills through their jewelry design practices from the perspective of their own art disciplines. A group of 25 students participated in the study, which was planned for three hours a day, one day a week, for a total of 28 weeks during the autumn and spring semesters of 2021-2022. In the study, we conducted interviews with designers, artists, and academicians about their production processes. The participants in the study were given the opportunity to experience jewelry design projects in a digital environment by teaching and using the “Nomad Sculpt” software. The participants presented their own jewelry design projects with the criticism system developed by Feldman which consists of description, formal analysis, interpretation and judgement stages, and dialogues in which learning processes questioned with this research program were also included in the evaluation process. This process was evaluated with an analytical approach by a committee of faculty members involved in the project. The study aimed to explore and reveal the efficiency of the interdisciplinary working processes of the participating students across all artistic production stages, the awareness of the principles and elements of art, and the connections between artistic production and theoretical knowledge. Some of the results obtained from the study were that the participants who expected to improve their design skills met these expectations, and that the participants in the study were able to produce discourse on their artistic productions with the attainment of interdisciplinary work.
The Investments Efficiency Toward Economic Growth: ICOR of the Republic of Croatia and Slovenia - Comparative Analysis
Authors: Mazllami Jeton
Published: November 2023

: Most developing and developed countries, today are faced with a lot of economic, social, and political challenges as a result of internal or external factors such as the World Financial Crisis and Covid19. In these circumstances, the crucial objective of any government is to improve the national economic performance by increasing domestics and foreign investments. Investments efficiency is the main pillar in the increase of the economic growth of any economy. This paper aims to measure the efficiency of the investments towards economic growth in the Republic of Croatia and Slovenia by applying a comparative analysis. The specific objective of our paper is to determine the best ICOR level, the correlation between ICOR and GDP, and the impact on the economic growth of both countries. The research methodology will include the analysis of the efficiency of the investment measured by the indicators Incremental Capital-Output Ratio (ICOR) based on the World Bank approach. The period of observation includes the period from the year 1995 to 2020. The investment efficiency (ICOR) in both countries is expected to move between 1 and 6. The findings of this research are that each one-point decrease of the ICOR level of Croatia increases the economic growth by 1.961 percent, while the ICOR level of Slovenia increases less the Economic growth by 0.259 percent.
Because Tumblr-Internet-Speak: Four Assumptions of Discourse Analysis Within New Rules of the English Language
Authors: Krndzija Nedima
Published: November 2023

The literature has described linguistic deviations from the conventional use of English in Computer-Mediated Communication (CMC) as distinguishing aspects of language used on the Internet. (Page, Barton, Unger, Zappavigna, 2014) The purpose of this paper is to analyse the unique language patterns seen on Tumblr, a popular microblogging platform, and how these patterns fit into four assumptions of discourse analysis as described by Rodney H. Jones (2009). Using a textual analysis method on a corpus of 60 texts extracted from Tumblr, this paper shows how four assumptions of discourse analysis can be found in Tumblr posts. The four assumptions of discourse analysis are that language is ambiguous, it is always in the world, it is used to show belonging to social groups, and it is never used alone. The ambiguity of language is taken advantage of, and Tumblr users use this ambiguity as a way of creating new vocabulary. New terms on Tumblr are coined and used by different social groups to show their association or aversion to said groups. Furthermore, textual analysis shows how Tumblr users mostly use language such as contractions, abbreviated forms, and acronyms in their blogs, which indicates that the said language is always in the world - the context in which, when, and for what a language is used determines what it signifies. Lastly, the analysis shows that the language is never used all by itself: non-standard use of punctuation adds tone to the text, and it functions as a ranting tone that impersonates rhetorical speech.
War in Afghanistan: A Look Back at Twenty Years of American Presence
Authors: Baĝ Mustafa , Delalić Selma , Tandir Nataša , Olovčić Adem
Published: November 2023

The history of Afghanistan is abundant in crises, coups, assassinations, political intrigues, as well as invasions and conquests. The last 40 years have been marked by long crises and conflicts: Soviet invasion 1979-1989, the civil war 1989-2001, the American invasion 2001-2021 with disastrous consequences for the country and the people. The invasion carried out in the name of ‘war on terrorism’, ‘bringing democracy’ and ‘freedom’, as a matter of fact, led to instability, turmoil, sectarian wars, deaths of tens of thousands of civilians and the formation of new terrorist organizations in the country, rather than peace and stability. War has become commonplace in Afghanistan. Once seen as the ‘shining star’ of Central Asia, Afghanistan is now known as the country exporting terrorism, drugs and refugees. The paper aims at showing causes and consequences of two decades long American presence in Afghanistan that left lasting imprint on Afghan society.
HALAL CRITICAL POINT ANALYSIS OF SOME TOAST SAMPLES IN CIBIRU DISTRICT, BANDUNG CITY
Authors: Mumtazah Muna , Wardatul Jannah Annisa , Mauludiyyah Inayatulloh Hilma , Supriyatna Ateng
Published: November 2023

Abstract : The halalness of a food product is still a hot topic in public discussion. The halal quality of food and beverage products does not always depend on the raw materials used. However, it can be known from the mixing materials used, starting from the production process to the distribution process. Muslims are required to eat food that is halal and thoyyib, the critical point of an important product. The critical point of halal is a stage of food production where there is a possibility for a product to become haram. The purpose of this study is to determine the critical point of halal toast products in the Cibiru area, Bandung City. The method used is direct field research by way of observation, interviews, and documentation related to the required data. Furthermore, data analysis was carried out and described in accordance with data collection when in the field. So that the results show that there are critical points in the composition of toast, namely plain bread, jam, and margarine as well as critical points in the tools used, namely baking sheets and brushes.
Historical Context and Culture of Remembrance and they Signifi- cance for Comparative Education
Authors: Nowakowska-Siuta Renata
Published: November 2023

The article presents a new approach to comparative education in the Polish comparative discourse, based primarily on the ideas of pedagogical constructivism, opening a discussion on a new method- ological paradigm, which is the place of historical context and memory in comparative research. In Polish comparative education there is a tendency to attach less importance to the role of history and memory for a comprehensive grasp of the meaning of the phenomena analyzed and the search for answers to important cognitive problems. The traditional approach is focused on the present and fu- ture perspective and this is how educational problems are perceived in the discourse of comparative education. Taking into account the importance of historical thinking in the methodology of compara- tive education is important insofar as it shows a wide context and helps understand rather than only present phenomena. The contextual analysis, including the embedding of phenomena in their logic of historical events, is the basic task of comparative education.
Serial jako medium edukacyjne, czyli młodzież i rodzina w serialach „Euforia” i „13 powodów”
Authors: Płowuszyńska Martyna
Published: November 2023

Popular culture surrounds us all and becomes an indispensable part of our lives, which is why it      is important to conduct research in this field. The article is based on two series dedicated to youth, Euforia and 13 Reasons Why. In this text, I described the educational potential of popular culture, introduced the phenomenon of the series and mentioned these types. Moreover, I included information about what attracts the viewer to this type of audiovisual messages. The dominant topic in this analysis of the series is the intra-family relations of young people. I described parenting styles, relationships in adolescent families, family types, conflict issues in families, and the trust and au- tonomy of adolescents. The crucial important issue of social, emotional and spiritual orphanage was raised, too.
Konteksty regionalne i tożsamościowe w tekstach piosenek śląskich raperów
Authors: Stępień Patryk
Published: November 2023

The article is devoted to identify the regional and identity contexts in the lyrics of songs by Silesian rappers. The selection of artists was based on two criteria: they were born or raised in Silesian district and they still live there and the second is the most popular (as an Silesian rapper) by listeners on Spotify.com in June 2022. Rap is a unique kind of music with a lot of listeners. Rap as a part of popular culture would be useful in education as an example of sharing regional values, mentality, desirable behaviors, and the position of the Silesian identity in their lives. The lyrics contain the artists’ points of view on reality, the living conditions, and probably include guidance for listeners. Silesian rappers and their experience of being Silesian and a sense of Silesian identity could be part of the lyrics.
Profilaktyka antymobbingowa – faktyczne działanie pracodawców czy fikcja?
Authors: Szczęsna Iwona
Published: November 2023

Mobbing as a pathological social phenomenon destroys the values that professional work offers people and violates their dignity. Therefore, the experience of mobbing in the workplace can with out doubt be classified as a critical life event. Analysis of the mobbing situation in terms of a critical life event helps to conclude that it carries the risk of regression, destabilization in personal and professional life, and halts development if a person does not cope with the effects and consequences of the situation. That is why anti-mobbing prevention in the workplace is so important. Unfortunately, the provision of article 94 §1 of the Labor Code, regulating the employer’s obligations in the field of mobbing in the work environment, is relatively general and is limited to indicating that the employer is obliged to prevent mobbing. There is no need to look for a provision in the labor code that would specify exactly what the employer’s actions should be understood under the obligation defined in this way. The article presents the results that are part of a broader study on anti-mobbing prevention in the workplace. The narratives of the respondents were analyzed through the prism    of the actual actions taken by employers in the context of anti-mobbing prevention. The research areas concerned: application of internal anti-mobbing policy, implementation of preventive training on mobbing and combating negative effects and other psychosocial risks in the workplace, and employers’ other anti-mobbing policies.
Młodzież NEET we fragmentarycznej rzeczywistości społecznej – próba charakterystyki
Authors: Stawska Marta
Published: November 2023

The following article is devoted to a social phenomenon that is increasingly becoming a point of interest to many research communities. It is a NEET youth Not in Employment, Education or Training), who simultaneously meet three conditions: they are not studying, not working and not training in formal education system. On the basis of literature on the subject and available data, the article discusses the theoretical aspects of the NEET phenomenon and fragmented social reality. In addition, statistics and methods of reintegration to facilitate re-entry into the labor market are presented.
Calibration – an under-appreciated component in the analytical process of the medical laboratories
Authors: Sonntag Oswald , Loh Tze Ping
Published: November 2023

Calibration of an analytical measurement procedure is an important basis for the reliability of patient results. Many publications and as well as procedures on how to estimate quality control and interpret those results have been become available over the years. In this publication we are focusing on the critical part of the calibration as there are no clear communication or guidelines on how to perform it. Usually only the recommendation of the reagent or instrument manufacturer is available. We would like to point out this gap to invite for a discussion and improvement of the current situation.
Molecular mechanism of colorectal cancer and screening of molecular markers based on bioinformatics analysis
Authors: Zhao Jikun , Kuang Dadong , Cheng Xianshuo , Geng Jiwei , Huang Yong , Zhao Haojie , Yang Zhibin
Published: November 2023

Genomics and bioinformatics methods were used to screen genes and molecular markers correlated with colorectal cancer incidence and progression, and their biological functions were analyzed. Differentially expressed genes were obtained using the GEO2R program following colorectal cancer chip data GSE44076 retrieval from the Gene Expression Omnibus gene expression comprehensive database. An online database (David) that combines annotation, visualization, and gene discovery was utilized for investigating genes. Pathway and protein analyses were performed via resources from the Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG). Visual analysis of the KEGG pathway was carried out according to ClueGO and CluePedia to establish the PPI network of gene interaction between pathways; the genes with the highest connectivity were screened by the molecular complex detection analysis method as Hub genes in this study; gene expression was verified by GEPIA online analysis tool, and Kaplan–Meier survival curve was drawn for prognosis analysis. By analyzing GSE44076 microarray data, 86 genes were selected, and colorectal cancer tissues’ upregulation was observed in 27 genes and downregulation in 59 ones. GO assessment revealed that the differentially expressed genes were basically correlated with retinol dehydrogenase activity, carbon dehydrogenase activity, collagen-containing extracellular matrix, anchored component of memory, and cellular hormone metabolic process. Moreover, the KEGG assessment revealed that the differential genes contained various signal pathways such as retinol metabolism, chemical carotenogenesis, and nitrogen metabolism. Through further analysis of the PPI protein network, 4 clusters were obtained, and 16 Hub genes were screened out by combining the degree of each gene. Through the analysis of each gene on the prognosis of colon cancer through the GEPIA online analysis website, it was found that the expression levels of AQP8, CXCL8, and ZG16 genes were remarkably associated with colon cancer prognosis (P < 0.05). Genomics and bioinformatics methods can effectively analyze the genes and molecular markers correlated with colorectal cancer incidence and progression, help to systematically clarify the molecular mechanism of 16 key genes in colorectal cancer development and progression, and provide a theoretically valid insight for the screening of diagnostic markers of colorectal cancer and the selection of accurate targets for drug therapy.
A layer potential approach to inverse problems in brain imaging
Authors: Asensio Paul , Badier Jean-Michel , Leblond Juliette , Marmorat Jean-Paul , Nemaire Masimba
Published: November 2023

We study the inverse source localisation problem using the electric potential measured point-wise inside the head with stereo-ElectroEncephaloGraphy (sEEG), the electric potential measured point-wise on the scalp with ElectroEncephaloGraphy (EEG) or the magnetic flux density measured point-wise outside the head with MagnetoEncephaloGraphy (MEG).
We present a method that works on a wide range of models of primary currents; in particular, we give details for primary currents that are assumed to be smooth vector fields that are supported on and normally oriented to the grey/white matter interface.
Irrespective of the data used, we also solve the transmission problem of the electric potential associated with a recovered source; hence we solve the cortical mapping problem.
To ensure that the electric potential and normal currents are continuous in the head, the electric potential is expressed as a linear combination of double layer potentials and the magnetic flux density is expressed as a linear combination of single layer potentials.
Numerically, we solve the problems on meshed surfaces of the grey/white matter interface, cortical surface, skull and scalp.
A main feature of the numerical approach we take is that, on the meshed surfaces, we can compute the double and single layer potentials exactly and at arbitrary points.
Because we explicitly study the transmission of the electric potential in head when using magnetic data, the coupling of electric and magnetic data in the source recovery problem is made explicit and shows the advantage of using simultaneous electric and magnetic data.
We provide numerical examples of the source recovery and inverse cortical mapping using synthetic data.
Reuocat tua forma parentem – Hasdrubals Fest, Scipios Besuch bei Syphax und ihre epischen Bezüge
Authors: Schwameis Christoph
Published: November 2023

This paper considers two scenes in Books 15 and 16 of the Punica of Silius Italicus: Hasdrubal’s celebration of the founding of Carthage with the ecphrasis of the general’s cloak (Sil. 15,410–440) and Scipio’s visit to the court of King Syphax (16,170–276). For both passages there are important reference texts in scenes of Vergil’s Aeneid and Statius’ Thebaid that have until now received no, or not enough, attention: Aeneas’ visit to the future Rome (Aen. 8,102–553) and the sacrifice of Eteocles (Theb. 11,205–238). After a brief assessment of the historiographical basis, I set out the influence in content and language of these reference texts on the two scenes. Further, I consider the adaptation of other epic pre-texts in the ecphrasis of Hasdrubal’s cloak and propose a new interpretation: the ecphrasis links Hasdrubal to Ganymede, Polyphemus and Cacus, and Scipio with Jupiter, Odysseus and Hercules. The study highlights positive and negative aspects of the pre-texts and shows the ambivalent characterisation of Silius’ Scipio, who is associated both with positive figures (Hercules and Aeneas) and with the sinister Polynices. The shared reference of the two scenes of the Punica has a linking, framing and preparatory function.
Kroatische Sprichwortvarianten bei der Erstellung des kroatischen parömiologischen Thesaurus
Authors: Varga Melita Aleksa , Babić Snježana
Published: November 2023

The project establishing the Croatian paremiological minimum and optimum began in 2014 during which valuable data was collected from 1,585 informants, who completed two sets of field questionnaires – the first and the second final text presentation of the proverbs occurring most frequently in the three biggest Croatian corpora (see Aleksa Varga and Keglević 2020a). The questionnaires were analyzed using the model analysis developed by Chlosta and Grzybek (see Chlosta and Grzybek 2005, 2015 and Grzybek 2012), based on a 4-code system. Since part of the analysis of both studies regarding the zero variant and the familiarity of Croatian proverbs have already been published (see Aleksa Varga and Keglević 2020b), the scope of this paper lies in analyzing the variations of the first, second, or third degree. As one of the goals of the research, apart from establishing the Croatian paremiological minimum and/or optimum, is also the construction of an electronic Croatian paremiological thesaurus, it is of utmost importance to analyze the proverb variations from the field questionnaires for inclusion in the database as well; i.e., to determine if they appear frequently enough alongside or instead of the proposed zero variant. Therefore, the present paper analyzes the Croatian proverb variants of the first, second, and third degree from the quantitative, qualitative, and corpus linguistic point of view, providing suggestions on further steps in constructing the Croatian proverbial thesaurus.
Process intensification in biopharmaceutical process development and production – an industrial perspective
Authors: Schaub Jochen , Ankenbauer Andreas , Habicher Tobias , Löffler Michael , Maguire Nicolas , Monteil Dominique , Püngel Sebastian , Stepper Lisa , Stiefel Fabian , Thoma Judith , Unsöld Andreas , Walther Julia , Wayne Christopher , Wucherpfennig Thomas
Published: November 2023

Process intensification aims to increase productivity in biologics manufacturing. Significant progress has been made in academia, the biopharmaceutical industry, and by the regulatory guidance since the 2000s. Process intensification can include all unit operations of a drug substance manufacturing process. The applied upstream concepts have consequences on the downstream process (DSP). The DSP process must manage larger product amounts while ensuring the required quality and impurity profiles, and cope with the available time frame as per scheduling requirements in a facility. Further, intensification in DSP is not based on a single technology only but rather on various technologies. This contribution provides an industry perspective on process intensification, describing basic concepts, technical and engineering aspects as well as the impact on the manufacturing process given existing facilities and a product portfolio to be manufactured. It also covers scientific approaches that support understanding and design of intensified bioprocesses. From an implementation perspective, the technologies used for intensification must be robust, scalable, and suitable for commercial manufacturing. Specific examples for a high seeding density fed batch (using N-1 perfusion) and a continuous process are provided for Chinese hamster ovary (CHO) cells producing therapeutic antibodies. Economic and sustainability aspects are addressed as well. Process intensification in an industrial environment is complex and many factors need to be considered, ranging from characteristics of a specific molecule to its commercial manufacturing at internal or external sites for global or regional markets.
Re-membering Publicness
Authors: Cooper Jayson
Published: November 2023

In this short multimodal text I scratch away and make visible the colonial and consumerist ideals of ownership that are etched over Southern landscapes; shaping the cultural commons and common worlds (Bowers, 2009; Hodgins, 2019). Colonial structures advance the enclosure and erasure of public spaces via a rhetoric of turning the earth to your advantage (Cooper, 2015). This views the South—Indigenous minds, bodies, and territories (Tuck & Yang, 2014) — as a table rasa waiting to be developed. The colonial project’s terraforming practices of places has distorted natural systems and patterns that manifest a public pedagogy of forgetting. This is more complex than environmental education and related discourses as it seeps across the political, social, environmental, ethical and the identities of contemporary Australian publicness (Fletcher et al., 2020). Refusing this narrative this text makes visible some wounds inflicted by the ongoing advancement of colonisation. Storying Country (Phillips & Bunda, 2018) through multimodality re-members and re-turns (Barad, 2014) the complexities of Place; to decolonise settler notions (Hamm, 2017). Decolonising publics is complex work. For sustainable futures all narratives of Place are important. This ethic calls for the refusal, resistance, and rejection of forgetting in order to come alongside Indigenous and Southern ways of knowing, being and doing (Martin, 2006). Staying with the always-already constitutions that generate public pedagogy learning ecologies relations with Country can be made visible to create new discursive practices through the arts. Doing this with Place allows for discourse on decolonising the public sphere. In this text I compose a multimodal text (Arnott & Yelland, 2020) that stories the palimpsestsous nature of being in relation-with Place through a pedagogy of intra-action (Cooper & Sandlin, 2020). Staying with the scarification and development of Joan’s/Jones creek; a seasonal creek in Wurundjeri Country (in the western suburbs of Naarm (Melbourne), Australia).
Study of eigen frequency In1-xGaxAsyP1-y 1.55 µm VCSEL with SiO2 /TiO2 dielectric Bragg reflector
Authors:   Laboratory of physics and semiconductor devices (LPDS),University of Bechar, P.O.BOX 417, Bechar 08000, Algeria, Missoum A. , Sabri N. G. ,   Laboratory of information processing and telecommunication (LTIT), University of Bechar, P.O.BOX 417, Bechar 08000, Algeria, Daoudi M. ,   Laboratory of physics and semiconductor devices (LPDS),University of Bechar, P.O.BOX 417, Bechar 08000, Algeria, Guedaouria H. ,   Laboratory of physics and semiconductor devices (LPDS),University of Bechar, P.O.BOX 417, Bechar 08000, Algeria, Benamara A. ,   Laboratory of Advanced Materials Physical Chemistry (LPCMA), University of Djillali Liabes, BP 89, Sidi-Bel-Abbes 22000, Algeria
Published: November 2023

In this work, we focused on investigating the eigen frequency and internal standing wave characteristics of a vertical surface cavity emitting laser operating at a wavelength of 1.55 µm. The design of the cavity involved determining the cavity length, selecting the material for the cavity spacer, and carefully placing the quantum wells within the cavity to achieve maximum overlap with the electric field. In our case, the choice of the dielectric Bragg mirror with SiO2/TiO2 layers helps in achieving high reflectivity and low optical losses. The quantum wells are strategically placed within the cavity to ensure maximum overlap with the electric field. This allows for efficient carrier injection and recombination, leading to laser emission. The specific composition of the quantum wells, In0.54Ga0.46As0.99P0.01 / In0.75Ga0.25As0.55P0.45, indicates the proportions of indium (In), gallium (Ga), arsenic (As), and phosphorus (P) in the material. These compositions are chosen to achieve the desired electronic band structure and emission wavelength. By studying the eigen frequency and internal standing waves in our designed laser cavity, our aim is to understand the resonant modes and behavior of light within the device. This knowledge is crucial for optimizing the laser's performance and improving its efficiency for various applications.
Effect of ratio gold nanoparticles on the properties and efficiency photovoltaic of thin films of amorphous tungsten trioxide
Authors:   Department of Physics, College of Education for Pure Science / Ibn Al-Haitham, University of Baghdad, Baghdad, Iraq, Mustafa M. H. , Shihab A. A. ,   Department of Physics, College of Education for Pure Science / Ibn Al-Haitham, University of Baghdad, Baghdad, Iraq
Published: November 2023

At a substrate temperature of 320 o C, a chemical spray pyrolysis approach was applied. to create tungsten oxide thin films on glass substrates with varying Au nanoparticle doping concentrations (0, 0.04 and 0.08 M) that have a thickness of roughly 250 nm. Investigated were the structural and optical characteristics. The films were amorphous to the pure films at the substrate temperature (320 °C), according to X-ray diffraction and remain so even after adding GNPs, because the WO3 structure is amorphous in all samples, whereas the cubic structure of the gold nanoparticles. The morphology of the films was examined using atomic force microscopy (AFM), which showed a decrease in the grain size of the films doped with gold compared to the thin films before the doping process. a UV-Vis spectrophotometer was used to examine the membranes' optical characteristics between the wavelengths of (300-1000) nm. was the optical energy gap of the films (3.23) eV for tungsten oxide film and decreased after adding nanoscale gold to (3.04, 2.95) eV for films doped with different proportions of Au NPs (0.04, 0.08 M), respectively. Hall testing confirms that with 8 (mM) Gold (Au) doping, WO3 material of the n type was obtained with a maximum carrier mobility of 219.92(cm2 /Vs) and conductivity of 6.52 (Ω.cm)-1 . The I-V characteristics of the photovoltaic formed under illumination were determined by measuring the incident power density (100 mW/cm2 ) at varied Au doping levels.
Radicle emergence test for soybean vigour testing
Authors: Gallo Carina , Magnano Luciana
Published: November 2023

This study was carried out to determine the use of single counts of radicle emergence to test seed vigour and estimate seedling field emergence of soybean (Glycine max) seed lots. Results of radicle emergence (RE) (production of 2 mm radicle) at 20°C for 48 hours and 25°C
for 24 hours, mean germination time (MGT), tetrazo lium vigour test (TZ) and field emergence (FE) were compared using nine soybean seed lots with standard germination above 80%. The single counts of RE performed at 20 and 25°C were significantly correlated with the MGT at the same temperature
(R2 = 0.82 and 0.89, respectively) and with the TZ vigour (R2 = 0.96 and 0.93, respectively). The RE counts at both temperatures also estimated the field emergence of the seed lots (R2 = 0.74 at 20°C and 0.68 at 25°C). The TZ vigour
results had a significant correlation with the seedling field emergence (R2 = 0.70). Results indicate that a single count of radicle emergence after 48 hours at 20°C or 24 hours at 25°C is an efficient option for soybean seed vigour assessment.