bluuebunny/crossref_metadata_2025 huggingface dataset:
Low Neonatal Circumcision Bleeding Rate in Patients Diagnosed with Delta-Storage Pool Deficiency Later in Life
Authors: Absi Hebah Al , Dagmar Stein
Published: September 2021

Introduction male circumcision is a common procedure, generally
performed during the newborn period. Few reports have described
circumcision in patients with bleeding disorders. Aim to determine
bleeding rate after circumcision in neonatal male subjects who were
diagnosed later in life with delta-storage pool disease (SPD). Methods
we retrospectively reviewed the medical records of male subjects
(<18 years of age) who were diagnosed with SPD later in life
and were circumcised at birth without hemostatic prophylaxis due to lack
of family history at that time from 2000-2020.
Intraoperative/postoperative bleeding and bleeding severity were the
main outcomes evaluated. Results 153 male subjects were included.
Circumcision was performed at a median age of 2 days (range, 1 day-4
months). The main indication for circumcision was parental request.
Median severity of granule deficiency was 2.76 dense granules/platelet
(range, 1.12-3.82 DG/Plt). None of the subjects had intraoperative
bleeding. Three subjects (2%) had postoperative bleeding and only one
(0.65%) required ER intervention to stop bleeding. Conclusion the
overall incidence of bleeding in our subjects with SPD who were
undiagnosed and untreated at circumcision, is comparable to that
reported for patients without a bleeding disorder.
The role of phylogeny and ecological opportunity in host-parasite interactions: network metrics, host repertoire, and network link prediction.
Authors: Cruz-Laufer Armando , Artois Tom , Koblmüller Stephan , Pariselle Antoine , Smeets Karen , Steenberge Maarten Van , Vanhove Maarten
Published: September 2021

Hosts and parasites have often intimate associations. Therefore, the
evolution of their interactions is crucial for understanding
species-rich host-parasite communities. Yet relatively few studies
investigate eco-evolutionary feedbacks in these systems as large
datasets remain scarce. Here, we explore African cichlid fishes and
their flatworm gill parasites (Cichlidogyrus spp.) including 9901
reported infections and 473 different host-parasite combinations
collected through a survey of peer-reviewed literature. We apply network
metrics, estimate host repertoires, and use network link prediction
(NLP) algorithms to investigate meta-community structures and their
predictors including evolutionary, ecological, and morphological
parameters. Host repertoire was mostly determined by the hosts’
evolutionary history. Both ecological and evolutionary parameters
predicted host parasite associations but many interactions remain
undetected according to NLP. We conclude that ecological opportunity
paired with ecological fitting has shaped interactions. The
cichlid-Cichlidogyrus network is a suitable study system for
eco-evolutionary feedbacks but taxonomic research remains key to finding
undetected interactions.
Outcome and safety of intracardiac echocardiography guided left atrial appendage closure within zero-fluoroscopy atrial fibrillation ablation procedures
Authors: chen yi he , Wang Liangguo , Zhou Xiaodong , fang ying , Su Lan , Wu Shengjie , huang weijian , Xiao Fangyi
Published: September 2021

Background: Simultaneous atrial fibrillation (AF) catheter ablation and
left atrial appendage closure (LAAC) is sometimes recommended for both
rhythm control and stroke prevention. However, the advantages of
intracardiac echocardiography (ICE) guidance for this combined procedure
have been scarcely reported. To evaluate the clinical outcomes and
safety of ICE guided LAAC within a zero-fluoroscopy catheter ablation
procedure. Methods and Results:From April 2019 to April 2020, 56
patients with symptomatic AF underwent concomitant catheter ablation and
LAAC. ICE with a multi-angled imaging protocol mimicking the TEE echo
windows was used to guide LAAC. Successful radiofrequency catheter
ablation and LAAC was achieved in all patients. Procedure-related
adverse event rate was 3.6%. During the 12-month follow-up, 77.8% of
patients became free of arrhythmia recurrences and oral anticoagulants
were discontinued in 96.4% of patients. No ischemic stroke occurred
despite two cases of device-related thrombosis versus an expected stroke
rate of 4.8% based on the CHA2DS2-VASc score. The overall major
bleeding events rate was 1.8%, which represented a relative reduction
of 68% versus an expected bleeding rate of 5.7% based on the HAS-BLED
score of the patient cohort. The incidence of iatrogenic atrial septal
defect secondary to a single transseptal access dropped from 57.9% at 2
months to 4.2% at 12 months TEE follow-up. Conclusion:The combination
of catheter ablation and LAAC under ICE guidance was safe and effective
in AF patients with high stroke risk. ICE with our novel protocol was
technically feasible for comprehensive and systematic assessment of
device implantation.
Diabetes, Drug Treatment and Mortality in COVID-19: A Multinational Retrospective Cohort Study
Authors: Nyland Jennifer E. , Raja-Khan Nazia T. , Bettermann Kerstin , Haouzi Philippe A. , Leslie Douglas L. , Kraschnewski Jennifer L. , Parent Leslie J. , Grigson Patricia Sue
Published: September 2021

Patients with type 2 diabetes mellitus (T2DM) are at
increased risk of severe COVID-19 outcomes possibly due to dysregulated
inflammatory responses. Glucose-regulating medications such as glucagon-like
peptide-1 receptor (GLP-1R) agonists, dipeptidyl peptidase-4 (DPP-4)
inhibitors, and pioglitazone are known
to have anti-inflammatory effects that may improve outcomes in patients with
SARS-CoV-2 infection. In a multinational retrospective cohort study, we used
the TriNetX COVID-19 Research Network of 56 large healthcare organizations to
examine these medications in relation to the incidence of hospital admissions,
respiratory complications, and mortality within 28 days following a COVID-19 diagnosis.
After matching for age, sex, race, ethnicity, body mass index, and significant
comorbidities, use of GLP-1R agonists and/or pioglitazone was associated with
significant reductions in hospital admissions (GLP-1R: 15.7% vs 23.5%; RR, 0.67
[95% CI, 0.57-0.79]; P <.001; pioglitazone: 20.0% vs 28.2%; RR, 0.71
[95% CI, 0.54-0.93]; P =.01). Use of GLP-1R agonists was also associated
with reductions in respiratory complications (15.3% vs 24.9%; RR, 0.62 [95% CI,
0.52-0.73]; P <.001) and incidence of mortality (1.9% vs 3.3%; RR, 0.58
[95% CI, 0.35-0.97]; P =.04). Use of DPP-4 inhibitors was associated
with a reduction in respiratory complications (24.0% vs 29.2%; RR, 0.82 [95%
CI, 0.74-0.90]; P <.001), and continued use of DPP-4 inhibitors after
hospitalization was associated with a decrease in mortality compared with those
who discontinued use (9% vs 19%; RR, 0.45 [95% CI, 0.28-0.72]; P
<.001). In conclusion, use of glucose-regulating medications such as
GLP-1R agonists, DPP-4 inhibitors, or pioglitazone may improve outcomes for COVID-19 patients with T2DM; randomized clinical
trials are needed to further investigate this possibility.
Samarbeid om rus- og psykiske helsetjenester – erfaringer fra en innovasjonsprosess i en storbykommune
Authors: Røste Rannveig , Bjørkquist Catharina
Published: September 2021

Collaboration has been emphasized as a solution for many complex problems, in both political agendas and research literature. Public reforms aim at coordination and integration of services for people with complex health and social challenges, such as addiction and mental health problems. How to organize services in a coordinated and integrated manner is for each local authority to determine. In this chapter, we examine an innovation process initiated by a large city in order to develop integrated services. By using the process approach as a method, this chapter provides in-depth insight into how different actors meet and collaborate on reorganizing the services and the challenges they encounter in their collaboration.
Bolig til brukere med omfattende rus- og psykiske lidelser
Authors: Hansen Gunnar Vold
Published: September 2021

This chapter addresses one of the biggest challenges for persons with dual diagnoses – the need for adapted housing. We take a close look at how housing needs are defined, allocation processes, and coordination with other relevant services. A major challenge is allocation of adapted housing, partly because many people with dual diagnoses are unable to function adequately in the housing they have at their disposal. The chapter concludes with the suggestion that one of the reasons why housing is so challenging is that those responsible for allocation do not have sufficient knowledge of the housing users and their needs. This challenge could be resolved by enabling more extensive cooperation between the various actors who provides services to the end users.
«Det nye paradigmet» i rus- og psykiske helsetjenester – utfordringer og muligheter
Authors: Bjørkquist Catharina , Ramsdal Helge
Published: September 2021

The purpose of this book has been to show how the challenges associated with services for people with complex needs, exemplified here by addiction and mental health disorders, are handled at the local level. The starting point was three characteristics of trends in national policy and organization of services for people with complex needs: decentralization, user participation and coordination. We argue that these characteristics represent conditions within the services for such disorders and also provide a framework for development within them. The characteristics are understood as entangled processes that constitute elements in the emergence of a “new paradigm” in the services, what is described as a focus on “locally based services”. The processes for change at the local level which we have studied show that institutional characteristics, based on different histories and traditions in the work with addiction and mental health disorders, are important for understanding how these change processes are organized. The three municipalities we studied all recognize that addiction and mental health disorders and illness are important societal problems that must be addressed locally. We can also state, however, that local strategies for achieving the goal of better coordination and integrated services evolve in very different ways.
Nasjonale veiledere – «soft governance» og «nudging»?
Authors: Ramsdal Helge , Bjørkquist Catharina
Published: September 2021

This chapter examines how addiction and mental health policy can be designed to meet the objective of the new paradigm of community-based services applying soft governance tools while maintaining the balance between hierarchical governance and local autonomy. Nudging is a specific tool within the framework of soft governance. Furthermore, such instruments leave great latitude for local authorities. We explore how we can understand the development towards today’s dominant ideological perspectives, i.e. normalization, empowerment, towards recovery and “the patient first”, as a development process where soft governance is the overriding concept, increasingly providing room for development of more specific strategies characterized by nudging. Finally, we discuss some implications of using such instruments in practice.
Trenger ROP-brukere en individuell plan?
Authors: Hansen Gunnar Vold
Published: September 2021

In this chapter, we take a closer look at experiences using individual plans and the role of the coordinator responsible for those participating in such plans. The starting point is that only a small number of service recipients with dual diagnoses have individual plans, while more than half of them have an appointed coordinator. This raises several questions. One is whether individual plans are a tool for service recipients or for service providers; another question is how coordinators can best assist service recipients with their daily challenges. The chapter concludes that the best help for service recipients with dual diagnoses is to have a coordinator who works as a “boundary spanner”.
Helhetlige tjenestetilbud i en liten kommune
Authors: Hansen Gunnar Vold
Published: September 2021

One of the three municipalities that participated in the ROPIT project was a relatively small one. In this chapter, we take a closer look at how the distinctive features of a small municipality can affect how services are provided to persons with dual diagnoses. It seems as though the work is characterized by collaboration between service providers and service recipients as well as a flexible and pragmatic approach within the services, but such flexibility is not explicit in the relation between the municipality’s other services. However, this is not a unique situation for small municipalities. There is reason to believe that larger municipalities do not necessarily provide better services for persons with dual diagnoses. Yet how they choose to organize their services according to given goals and priorities in order to achieve coordinated services will vary.
Molecular genetic methods in biomedical research. Part III: human gene diagnostics in clinical practice
Authors: Volkov A. N. , Nacheva L. V.
Published: September 2021

Application of molecular genetic methods in the diagnosis and treatment of human diseases is extremely wide due to a huge amount of hereditary information contained in the human genome. Gene diagnostics allows establishing predisposition to diseases, identification of genetic abnormalities and prediction of pathological outcomes. In addition, gene diagnostics also enables prediction of the individual response to treatment in order to achieve the maximum therapeutic effect. Among all molecular genetic methods, polymerase chain reaction (PCR) diagnostics is a leading approach. Technical simplicity, low cost, high sensitivity and reliability of the method have made PCR diagnostics a routine modality for the risk assessment, diagnostics, and monitoring of the treatment efficiency. Here, we consider the application of PCR diagnostics for the abovementioned tasks and talk about the real-life examples of detecting mutations and chromosomal aberrations which may cause a disease. Further, we discuss the prospects of using a semi-quantitative PCR in medical practice and focus on pharmacogenetics as a key component of a personalised therapy. The lecture is aimed primarily at biomedical students and physicians and represents a continuation of the previous lectures published in Fundamental and Clinical Medicin.
Persisting multiple organ dysfunction syndrome in a patient with severe polytrauma: a case report
Authors: Grigoriev E. V. , Voevodin S. V. , Kovalenko A. V. , Rudakova D. A.
Published: September 2021

Persistent multiple organ failure is a new phenotype of a critical patient capable of leveling all the initial successes in treating a patient in the intensive care unit, which is associated with an increase in the need for methods of organ function replacement, the development of cognitive deficits, muscle weakness and polyneuropathy of critical care. A case study is presented that demonstrates the effectiveness of primary resuscitation of a patient with severe polytrauma with further persistence of multiple organ failure and the need for long-term therapy aimed at recovering a critical patient and with an emphasis on drugs affecting cognitive function.
COVID-19 in patients with tuberculosis: epidemiological and clinical features
Authors: Lebedeva I. B. , Osintseva I. Yu. , Bondarenko T. E. , Pyanzova T. V. , Brusina E. B.
Published: September 2021

Aim. To study the epidemiological and clinical features of COVID-19 among patients with tuberculosis.

Materials and Methods. We studied the incidence of COVID-19 in various population groups in Kemerovo Region in 2020 (from March, 13 to December, 31). The study cohort consisted of 3929 tuberculosis patients, including 113 with a verified COVID-19 diagnosis. The control cohort included tuberculosis-free subjects with COVID-19 (25,774 individuals). Out of these subjects, we enrolled 71 patients with tuberculosis and 71 age- and gender-matched controls. All patients underwent complete blood count, urinalysis, biochemical analysis, and coagulation testing.

Results. The incidence of COVID-19 in patients with tuberculosis was 2.96-fold higher than in the tuberculosis-free population (2876.05 and 971.17 per 100,000 population, respectively). In patients with tuberculosis, the highest incidence of COVID-19 was recorded in two age categories: from 18 to 29 years and ≥ 65 years of age. In tuberculosis patients, COVID-19 was mostly mild, was characterised by a 9.2-fold lower frequency of pneumonia, 11.8-fold less use of antibiotics, and oxygen therapy was required only in 1.41% of cases in comparison with 16.9% in the tuberculosis-free subjects. In addition, patients with tuberculosis less often suffered from hyperthermia, cough and weakness. Regarding the comorbid conditions, patients with tuberculosis showed lower prevalence of arterial hypertension, chronic heart failure, peripheral artery disease, and obesity. Further, patients with tuberculosis generally had higher glomerular filtration rate and rarely had neutrophilia or lymphopenia when compared with the control individuals with COVID-19, although having higher fibrinogen and aspartate aminotransferase serum levels.

Conclusion. Tuberculosis is a risk factor of COVID-19 but not a predictor of morbidity and mortality from this disease.
Epidemiological features of community-acquired mycoplasma pneumonia
Authors: Koshkarina E. A. , Strazhnova O. A. , Sharabakina M. A. , Chekanina O. M. , Krasnov V. V. , Zubarov P. G. , Kovalishena O. V.
Published: September 2021

Aim. To analyse an epidemic process of community-acquired mycoplasma pneumonia in the Volga Federal District and the Nizhny Novgorod Region.

Materials and Methods. We retrospectively analysed statistical reporting forms and electronic databases for 2012-2019 which included 443 cases of community-acquired mycoplasma pneumonia (349 foci and 4 outbreaks). In 2020, we assessed aetiology of community-acquired pneumonia in hospitalized patients of all ages who were diagnosed with a radiologically confirmed pneumonia (152 cases). In 2021, we carried out a microbiological study of pneumonia-causing pathogens in the nasopharynx among the healthy population (325 cases).

Results. Average long-term incidence of community-acquired pneumonia in Nizhny Novgorod Region for 2012-2019 was 3.4 per 100,000 population (95% CI = 0.3-6.5, p < 0.001), with a pronounced upward trend. In general, the aetiology of community-acquired pneumonia in the Nizhny Novgorod Region in 2019 was established at 25.81 ± 0.7% cases. M. pneumoniae accounted for 8.00 ± 0.43% cases (56.72 ± 2.53%) of all aetiologically defined communityacquired pneumonias. In children, the aetiology was determined in 93.1 ± 2.5% cases, of which M. pneumoniae accounted for 13.8 ± 3.5% cases (14.6 ± 3.74% of all community-acquired pneumonias).

Conclusion. Mycoplasma pneumonia is responsible for a significant proportion of all community-acquired pneumonias in Nizhny Novgorod Region. Notably, there is a low detection rate of mycoplasma pneumonia in certain territories that might explain an uneven distribution of associated morbidity.
Innovations in higher education in Ukraine (2011-2021): trend analysis
Authors: Ridei Nataliia , Viktorova Lesia Viktorivna , Chumak Mykola Yevgeniyovych , Kondur Oksana , Kanova Liudmyla Petrivna
Published: September 2021

Innovation - an important aspect of the functioning of the modern education system. The article analyzes innovative trends in higher education in Ukraine over the past 10 years. Ukrainian innovations in higher education are considered in the context of European and world trends and standards. The analysis and generalization of materials on the subject revealed five educational trends: convergence of academic training in professional practice, application of competence approach in assessing learning outcomes, growth of students' independent work, increase of creative component in learning, readiness to function in conditions of uncertainty. Each trend is analyzed according to the scheme: necessity of innovations, content of trends, specific variants of trend implementation. In recent years, higher education institutions have been increasingly stimulating both students and teachers to innovate.
What drives the dividend decisions in BRICS countries?
Authors: Mrzygłód Urszula , Nowak Sabina , Mosionek-Schweda Magdalena , Kwiatkowski Jakub M.
Published: September 2021

Research background: We examine the dividend payout policies across companies listed on the main stock exchanges in Brazil, Russia, India, China, and South Africa (BRICS). Unlike the highly developed capital markets, the literature regarding dividend policy on BRICS? stock exchanges is scarce. 

Purpose of the article: The purpose of this paper is threefold: verification of the existence of dividend smoothing pattern; selection of the significant drivers that affect both dividend levels and dividend smoothing; examination of differences between dividend policy of cross- and single-listed companies.

Methods: Based on a dataset of 564 companies that paid dividends for at least 11 consecutive years in the period of 1995?2015, we apply a GMM two-step estimator to assess the speed of dividend adjustment (SOA) coefficient. Further we employ the linear panel regression to indicate the individual and market determinants of the dividend levels and SOAs. In the latter case, we base on time series of the SOAs obtained from the rolling estimation technique. Finally, we conduct separate estimations for cross-listed companies.

Findings & value added: We confirm a moderate level of dividend smoothing within BRICS countries. Among the firm-level characteristics affecting the SOA the most important are: ownership dispersion, age and size of a firm, retained earnings, leverage, long term debt, asset tangibility, liquidity risk ratio, and issuing the depositary receipts (DR). Two relevant market factors are found: market capitalisation and turnover in relation to GDP. Similar characteristics have a significant impact on dividends? levels in the entire sample, whereas in the subsample of cross-listed companies fewer variables are significant. Our paper is the first comprehensive attempt to investigate the dividend policy and determinants of dividend smoothing among BRICS countries.
Quo Vadis, earnings management? Analysis of manipulation determinants in Central European environment
Authors: Valaskova Katarina , Adamko Peter , Frajtova Michalikova Katarina , Macek Jaroslav
Published: September 2021

Research background: The paper investigates the earnings management phenomenon in the context of Central European countries, attempting to identify the factors and incentives that can influence earnings management behavior on a sample of 8,156 enterprises from Slovakia, the Czech Republic, Hungary, and Poland.

Purpose of the article: The main purpose of the manuscript is to prove that there are significant differences in earnings management practices (measured by discretionary accruals) across the countries and to find the firm-specific features that influence the way enterprises manage their earnings.

Methods: The modified Jones model was used to calculate the discretionary accruals, which are further analyzed across the countries. The statistically significant differences were confirmed across the countries. Thus, the impact of the economic sector, firm size, firm age, legal form, and ownership structure on earnings management behavior is studied by the Kruskal-Wallis test. The Dunn-Bonferroni post hoc tests then revealed the significant differences across the categories of the investigated earnings management determinants. To find the association between the particular earnings management practice (income-increasing or income-decreasing manipulation), correspondence analysis was used to visualize the mutual relations.

Findings & value added: The results of the realized investigation revealed that the economic sector is one of the most important earnings management determinants, as its statistical significance was confirmed in each analyzed country. The correspondence analysis determined specific sectors, where income-increasing manipulation with earnings is practiced (NACE codes F, J, K, M, N), and vice versa, income-decreasing earnings management is characteristic for enterprises in sectors A, C, D, G or L. In specific economic conditions, firm size is also a relevant indicator (Hungary), or firm age and legal form and ownership structure (Poland). The recognition of crucial earnings management incentives may be helpful for authorities, policymakers, analysts and auditors when identifying various techniques and practices of earnings manipulation which could vary across the sectors and taking necessary measures to mitigate potential financial risks.
Numerical simulation and calibration of a single seam WAAM process with a commercial and an open source software
Authors:   Professorship of Virtual Production Engineering, Chemnitz University of Technology, Bauer Alexander , Scharf Ronny ,   Professorship of Welding Engineering, Chemnitz University of Technology, Hälsig André ,   Professorship of Welding Engineering, Chemnitz University of Technology, Awiszus Birgit ,   Professorship of Virtual Production Engineering, Chemnitz University of Technology
Published: September 2021

This paper is dealing with the comparison of the FEM result quality between a commercial tool and an open source software with regards to the numerical simulation of a single seam WAAM process. For this purpose, an experimental WAAM process was conducted by a welding robot on a 1.4404 (316L) base plate with a 1.4404 (316L) welding wire, connected with the associated measurement equipment. Furthermore, the equivalent setup was transferred in the FEM tools Simufact Welding and Elmer FEM, using the same parameters for both simulations. The calculations show, that both programs are able to generate high quality results with a good accordance to the temperature development within the experimental processes. In summary it can be said, that both programs offer advantages and the decision what tool has to be used depends on the requirements and the possibilities of the user.
Effects of high-temperature operating conditions on the through-plane gas permeability of gas diffusion layers used in PEFCs
Authors:   School of Mechanical Engineering, College of Engineering, Universiti Teknologi MARA, Pasir Gudang Campus, Malaysia, Raja Arif Raja Muhammad Aslam
Published: September 2021

In order to simulate the effects of high-temperature operating conditions on the through-plane gas permeability of gas diffusion layers (GDLs) used in polymer electrolyte fuel cells, uncoated and coated GDLs were heated at various temperatures (i.e. 200, 500 and 800 °C). The results show that the through-plane gas permeability of the uncoated GDLs generally increases after higher temperature treatment. However, the coated GDL displays a different trend: the through-plane gas permeability increases with increasing temperature treatment to 200 and 500 °C, but then decreases after heat treatment at 800 and 1000 °C. With the assistance of SEM images, the above results are discussed.
Evaluation of Students’ Performance in Poster Presentations Using Fuzzy Evaluation Method
Authors: Abd Aziz Khairu Azlan , Mohd Idris Mohd Fazril Izhar , Wan Daud Wan Suhana , Sudin Muhamad Amirul
Published: September 2021

Poster presentation encompasses many elements such as the organization of poster, the content related to the title proposed, the appearance and the written word. Usually, the poster presentation is used as a platform for student to present their final year project or any other competitions. Students will be evaluated based on the criteria that meets the requirements proposed by the panels or judges. However, their performance in poster presentations does not provide the suitable techniques to estimate the actual value since it involves the elements of fuzziness.  In this study, the fuzzy evaluation technique will be applied to measure the performance of the poster presentation. The motivation behind poster presentation is to determine the performance of students using fuzzy evaluation method. The objective of this study is to compare the results between using conventional method and fuzzy evaluation method.  The method consists of normalizing the marks, developing the graph of fuzzy membership function, calculating the degree of satisfaction, and finalizing the actual marks. We believed that the result from this study could be able to measure the better output with the consideration of linguistic terms includes excellent, good, moderate, satisfactory, and so on. This method also can be an alternative way to evaluate the performance of the poster presentation.
Performance of Unit Trust Funds between Conventional and Islamic Funds in Malaysia using Data Envelopment Analysis
Authors: Maamor Nahamizun , Fathul Ariffin Anas , Teoh Yeong Kin  , Abu Hasan Suzanawati
Published: September 2021

This study aims to analyse the current performance of unit trust funds between conventional and Islamic funds using data envelopment analysis because most Malaysians are incapable to distinguish between conventional and Islamic unit trust funds performances since they tend to assume both funds perform similarly. This paper uses 20 authorised funds by the Securities Commission Malaysia (SC) for three years by using trailing data that consists of volatility element as input and total return as output. Indeed, the funds selected do not mix asset classes of funds, instead relying solely on equity funds to create a fair and reasonable ranking. The study employs Data Envelopment Analysis by testing two different models, namely Charnes, Cooper, and Rhodes input oriented (CCR-I) model and Banker, Charnes, and Cooper input oriented (BCC-I) model. The use of two models in this study is to ensure that the results of the ranking analysis are more accurate and precise. Both models employ the input-oriented model function as a means of maximising efficiency in order to increase the number of fairies. The efficiency of Islamic funds is more consistent than that of conventional funds for both models, as several Islamic funds maintain their position at the top of the efficient rank. However, there is a significant increase in conventional funds because 80% of the selected conventional funds that are not efficient in the CCR-I model achieve the efficiency level in the BCC-I model. As a result, there are four unit trust funds that are consistent in occupying efficiency level when tested for both CCR-I model and BCC-I model whereby three out of four are Islamic funds while the other is conventional fund. The Islamic funds consist of Apex Dana Aslah, BIMB i Growth Fund, and Maybank Malaysia Growth-I Fund while KAF Tactical Fund is conventional fund. Ultimately, it is concluded that Islamic funds perform better than conventional funds in Malaysia for the 3 years period ending 31 March 2021.
Interactive Design in Enhancing User Experience in Museum
Authors: Md Nor Romiza , Abdul Razak Muhammad Hafizuddin
Published: September 2021

A museum can be a suitable context to experiment with a new interaction technique which guiding visitors and improving their experience for a successful learning environment also to enrich user experience. Mobile technology is used to enhance user experience in a cultural environment that offers more information than physically exposed technology. Therefore, the introduction of augmented reality (AR) that allow visitor to experience interaction in a way that increased knowledge, learning and give additional information with any artefact exhibitions they interact in the museum is applied in this project. The objectives of this research are to develop an interactive design in enhancing user experience in artefact display and evaluate user experience. ADDIE Model is applied as the methodology that consists of five phases which are analysis, design, development, implementation, and evaluation. Principles of Interactive Design is utilized in designing the mobile AR application and developed using Unity, Blender and Vuforia. User Experience evaluation method is conducted where findings shows that most respondents are satisfied, and usage of mobile AR has enhanced their experience through navigation during museum visit that also give a lot of new insight on historical artefact that being displayed.
Integrating Constructivist Learning Environments (CLEs) in Designing a Multimedia Learning Application for Cyber-Bullying Intervention
Authors: Abdul Wahab Nadia , Osman Aznoora , Ibrahim Norfiza , Md Ilyas Siti Sarah
Published: September 2021

Constructivism is a learning theory that emphasizes learners’ intervention through self-guided exploration, reflection, and evaluation. This study discusses on the integration of the Constructivist Learning Environments (CLEs) in designing a multimedia learning application for cyber-bullying intervention among adolescents. The application has been evaluated using Alpha Testing and Beta Testing technique to ensure its quality. From this evaluation, the researcher was also able to identify weaknesses or problems associated with the usage of the application, from the viewpoint of the content and multimedia expert and also the target user group which are the adolescents. By integrating CLEs, it is expected that knowledge and awareness is constructed by the learners as they reconcile new information with past experiences, analyze various source materials, and work collaboratively with others. As CLEs stimulates active learning, it is hoped that leaners will develop advanced skills such as critical thinking, analysis, evaluation, and creation. As CLEs promotes diverse viewpoints, it encourages students to reflect, evaluate their work, and identify intermediary skills to acquire based on their needs. It is also expected that the development of the multimedia app in this study will contributed to an increase in the number of computer-based applications intended to expose adolescents to the issue of cyber-bullying, which is still under-developed, particularly in the context of adolescents in Malaysia.
Healthy Management of Menopause: Exploring Issues and User Requirements for Mobile Intervention
Authors: Osman Aznoora , Ahmad Noraimi Nur Emieliana Izzatie , Abdul Wahab Nadia
Published: September 2021

Designing and developing a mobile health intervention that focuses on menopausal symptom management and emotional support for women should be grounded by some knowledge about their problems and needs. Therefore, to gather information about the issues surrounding women in their menopausal phase, review of literatures pertaining to the topic was conducted, followed by a brief preliminary investigation (PI) using online survey method which was administered to Malaysian women for two weeks.  The purpose of PI was to examine their awareness about menopause, namely its phases and symptoms management, as well as methods of information searching on menopause. Respondents were also inquired about their requirements from mobile app to support management of menopause. A total of 30 respondents answered the survey, with majority of them were between the ages of 40 and 59 years old. It was discovered that menopausal women had experienced variety of symptoms, some could be intense more often than the others, and they use diary or book to record these symptoms, which is deemed ineffective. It is imperative to help Malaysian women to manage this unavoidable phase of their lives in a more convenient approach. Therefore, a mobile app that supports symptoms management, and provides educational and motivational tips in Malay language is proposed.
El carácter múltiple de la racionalidad estatal: ministerios, funcionarios y desafíos de gobierno en la Argentina
Authors: Gené Mariana , Heredia Mariana , Perelmiter Luisina
Published: September 2021

Los trabajos que describen el sistema político en la Argentina suelen asumir o subrayar la concentración de la toma de decisiones y el carácter presidencialista de la autoridad pública. Sin embargo, la actividad de gobierno conlleva una complejidad y una diversidad de mediaciones que este supuesto no capta. Considerando a los ministerios como una de las principales mediaciones de la decisión gubernamental, y sobre la base de tres estudios de caso en áreas muy distintas del gabinete nacional –Economía, Interior y Desarrollo Social–, este artículo analiza los saberes y destrezas que caracterizan a los funcionarios, los interlocutores relevantes de cada cartera, los atributos institucionales de las mismas y los desafíos de gobierno que enfrentan en diversas situaciones históricas. A partir de ese análisis se identifican tres tipos de racionalidades –experta, pragmática y sensible– y se destacan las ventajas de una concepción plural de la racionalidad estatal.
Discusiones doctrinales y problemas de traducción. La representación de la Santísima Trinidad, la virgen María y los ángeles en La fazienda de Ultramar
Authors: Marti Melisa Laura
Published: September 2021

La fazienda de Ultramar es un texto del siglo XIII que traduce la Biblia a la manera de los itinerarios o guías de peregrinos medievales: en él, la selección de pasajes de la Escritura está motivada por la geografía de Tierra Santa, que orienta el recorrido por los relatos bíblicos. El objetivo de este trabajo será profundizar en las operaciones discursivas que diferencian a La fazienda de Ultramar de sus fuentes y de otros romanceamientos, y que reflejan las dificultades que enfrentaban los primeros traductores de la Biblia a las lenguas vernáculas. Nos centraremos específicamente en los aspectos que se vinculan con los debates de índole doctrinal y las discusiones teológicas propias del momento de redacción de la obra. Por ello, analizaremos la representación de la Santísima Trinidad, la Virgen María y los ángeles, augurando que nos permitirá conocer el sistema cultural en que se ubicaba el autor y su modo de trabajo en tanto traductor.
Experimental Research of Paperboard Cutting in Die Cutting Press with the Screw–Nut Transmission of Drive Mechanism of a Movable Pressure Plate
Authors: Ternytskyi Serhii , Rehei Ivan , Kandiak Nazar , Radikhovskyi Ihor , Mlynko Oksana
Published: September 2021

This paper reports experimental research of torques during paperboard cutting in the die cutting press with the screw–nut transmission in the drive mechanism of the movable pressure plate. The purpose of the study is to substantiate the practical implementation of the pressure plate drive mechanism with the use of screw–nut transmission for the production of cartons of paperboard blanks. The manufactured experimental bench for the research of paperboard blanks provides the possibility of getting dependencies of loads on different parameters of the die cutting process. The developed method of the experimental research envisages the use of the strain gauge method and the wireless module for data measurement and software for its processing that allow getting trustworthy results with minimum faults. As a result of experimental research studies, the impact of paperboard thickness and cutting velocity on torque values has been established. Results of experimental research allow getting trustworthy and systematised information about torque values depending on the thickness of the paperboard, the paperboard fibre direction and pressure plate displacement velocity. It is established that torque values on drive shaft during die cutting of paperboard blanks made of folding boxboard with thickness that lay in range of 0.3–0.7 mm. Experimental research studies show the impact of rotation speed of a drive shaft of the pressure plate drive mechanism on the torque value. The article shows the workability of the designed device with screw–nut transmission in the drive mechanism of a movable pressure plate.
Psychopathological conditions and somatic consequences of a suicide attempt with a corrosive substance in a patient suffering from long-lasting paranoid schizophrenia - a case study
Authors: Romaniuk Małgorzata , Poleszak-Szabat Julita , Krukow Paweł
Published: September 2021

Background: Schizophrenia is a chronic mental illness that affects 20 million people worldwide. Patients diagnosed with paranoid schizophrenia are characterized by cognitive deficits and the so-called negative symptoms, which significantly lower their quality of life and have implications for their independence and ability to fulfill various social roles.

Aim: This study aims to present the case of a 49-year-old woman who has been suffering from schizophrenia for a long time and, due to a psychotic exacerbation with delusions and auditory hallucinations in the form of ordering voices, attempted suicide by ingesting a highly corrosive chemical agent used for unblocking pipes (the so-called “mole”).

Case report: The patient was admitted to the 1st Department of Psychiatry, Psychotherapy and Early Intervention of SPSK 1 in Lublin for psychiatric treatment, after being transferred from the SPSK 1 Surgery Clinic, where she was initially admitted after the suicide attempt.

Discussion: The psychotic exacerbation in the patient could have resulted from sensory deprivation due to her feeling of loneliness and deep social isolation.
Constraints on the use of the plural morpheme men in spoken Mandarin
Authors: Cook Angela
Published: September 2021

This study returns to the oft-debated question of grammatical number and plurality in Modern Standard Chinese and attempts to shed new light on the constraints operating on the plural marker men by analysing its use in a corpus of half a million characters of spoken data. Data from the present research indicate that the plural morpheme men is less sensitive than previously assumed to a number of constraints outlined in the standard literature, including structural constraints involving NPs with quantifiers and explicit number expressions. At the same time, it is also more sensitive to a range of other factors that have hitherto been largely overlooked, including parallelism, the length of NP modifiers and lexical diffusion. The findings also suggest that the morpheme men is not used only to indicate plurality and collectivity but may have a number of other roles as well, such as functioning like a diminutive suffix and contributing to the organization of discourse and information structure.
Efektivitas Sistem Pengelolaan Sampah Berbasis Masyarakat (Studi Kasus: Desa Sanur Kaja Kota Denpasar)
Authors: Dewi Ni Putu Amelia Panida , Madrini Ida Ayu Gede Bintang , Tika I Wayan
Published: September 2021

ABSTRAK

Desa Sanur Kaja memiliki satu depo pengelolaan sampah khusus untuk menangani sampah yang dihasilkan oleh masyarakat desa yang bernama Depo Cemara. Berdasarkan penelitian sebelumnya diketahui bahwa kegiatan yang berjalan di Depo Cemara menjadi kurang efisien karena tidak semua masyarakat desa memilah dan menerapkan prinsip 3R (reduce, reuse, dan recycle) dalam pengelolaan sampah rumah tangga. Penelitian ini bertujuan untuk mengidentifikasi sejauh mana efektivitas sistem pengelolaan sampah yang sudah dilakukan oleh masyarakat Desa Sanur Kaja dengan membandingkan jumlah sampah yang dikelola oleh rumah tangga dengan prinsip 3R dengan jumlah sampah yang terbuang sehingga diperoleh persentase reduksi sampah. Pengumpulan data diperoleh dengan menyebar kuesioner kepada responden yang ditentukan dengan teknik purposive sampling. Data yang diperoleh kemudian dihitung dengan analisis kesetimbangan massa sampah lalu dianalisis lebih lanjut dengan metode analisis statistik deskriptif. Hasil penelitian terhadap 96 rumah tangga menunjukkan bahwa pengelolaan sampah berbasis masyarakat memiliki efektivitas yang rendah karena reduksi sampah yang terjadi hanya 22,5 persen dalam satu hari dan responden yang melakukan pemilahan sampah rumah tangga sebanyak 44 persen. Masyarakat menyatakan setuju terhadap rencana penerapan prinsip 3R dalam pengelolaan sampah rumah tangga serta menganggap penting ditambahkannya fasilitas-fasilitas pendukung pengelolaan sampah.

 ABSTRACT

Sanur Kaja Village has a special waste management facility for processing waste produced by the village community, namely Depo Cemara. Based on previous research, it is known that activities that are running at Depo Cemara are less efficient because not all village communities sort waste and apply the 3R (reduce, reuse, and recycle) principle in household waste management. This study aims to identify the effectiveness of the waste management system that has been implemented by the people of Sanur Kaja Village by comparing the amount of waste managed by households with the 3R principle with the amount of waste wasted in order to obtain a percentage of waste reduction. Data collection was obtained by distributing questionnaires to respondents who were determined by purposive sampling technique. The data obtained were then calculated by analyzing the mass balance of waste and then further analyzed using descriptive statistical analysis methods. The results of research on 96 households show that community-based waste management is still not effective because the percentage of waste reduction that occurs in one day only 22,5 percent and respondents who sort household waste are 44 percent. The community agreed to the plan to implement the 3R principle in household waste management and considered it important to add supporting facilities for waste management.
A Patient with Typhoid Hepatitis
Authors: Arfijanto M Vitanata , Rindryastuti Isty
Published: September 2021

Typhoid hepatitis is typhoid fever accompanied by symptoms of jaundice, hepatomegaly and abnormal liver function tests. The incidence varies between 0.4% -26% of typhoid fever patients. We report a case of a 34-year-old male, presented with fever, epistaxis, gastrointestinal symptoms, thrombocytopenia and elevated AST/ ALT, thus the patient was first diagnosed as dengue hemorrhagic fever grade II. On day 9th the signs and symptoms were persisted, Ig M and Ig G Dengue was negative. Then we evaluated the virus marker for hepatitis and blood culture. The results were negative for HBsAg, anti HCV and Ig M anti HAV, but Salmonella typhi detected on blood culture. The patient was treated with ceftriaxone 1000mg bid iv and get better then discharged from hospital.
Features of ozone effect on oxygen-dependent processes in the blood under hypoxic conditions
Authors: Zinchuk V. V. , Biletskaya E. S.
Published: September 2021

Introduction. Ozone is a physiological factor that can change hemoglobin oxygen affinity and the formation of gaseous transmitters (NO, H2S). The aim is to study the effect of ozone with gaseous transmitters donors on oxygen-dependent processes in the blood under hypoxic conditions in vitro. Materials and methods. Blood samples were divided into 6 groups of 3 ml each. Groups 2, 4, 5, 6 were pretreated with a deoxygenating gas mixture (5.5 % CO2; 94.5 % N2). In groups 3, 4, 5, 6, ozonized isotonic sodium chloride solution (with an ozone concentration of 6 mg/l) was added, and in groups 5 and 6, the donors of gas transmitters nitroglycerin and sodium hydrosulfide, respectively, were additionally introduced. Results. Pre-deoxygenation reduces the effect of ozone on oxygen transport in the blood. Nitroglycerin prevents this effect. The action of ozone under hypoxic conditions leads to an increase of content of NO3-/NO2- and H2S, and combination with nitroglycerin and sodium hydrosulfide increase these parameters. Deoxygenation due to ozone reduces parameters of lipid peroxidation (malonic dialdehyde, diene conjugates), retinol and α-tocopherol, and the same result in the nitroglycerin group. Conclusion. Under hypoxic conditions, a decrease in the effect of ozone on oxygen-dependent processes is reported. Nitroglycerin reduces its manifestation, while sodium hydrosulfide does not have a similar effect.