bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Methods from Novel Targeting of Phospho-cMET Overcomes Drug Resistance and Induces Antitumor Activity in Multiple Myeloma
Authors: Moschetta Michele , Basile Antonio , Ferrucci Arianna , Frassanito Maria Antonia , Rao Luigia , Ria Roberto , Solimando Antonio Giovanni , Giuliani Nicola , Boccarelli Angelina , Fumarola Fabio , Coluccia Mauro , Rossini Bernardo , Ruggieri Simona , Nico Beatrice , Maiorano Eugenio , Ribatti Domenico , Roccaro Aldo M. , Vacca Angelo
Published: April 2023

PDF file, 121K.
Supplementary Figure 3 from Clinical Significance and Prognostic Value of microRNA Expression Signatures in Hepatocellular Carcinoma
Authors: Wei Rongrong , Huang Guo-Liang , Zhang Mei-Yin , Li Bin-Kui , Zhang Hui-Zhong , Shi Ming , Chen Xiao-Qian , Huang Long , Zhou Qing-Ming , Jia Wei-Hua , Zheng X.F. Steven , Yuan Yun-Fei , Wang Hui-Yun
Published: April 2023

PDF file, 118K, The relationship between 20-miRNA signature risk score and survival status of HCC patients.
Supplementary Table 1 from Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents
Authors: Mao Muling , Tian Feng , Mariadason John M. , Tsao Chun C. , Lemos Robert , Dayyani Farshid , Gopal Y.N. Vashisht , Jiang Zhi-Qin , Wistuba Ignacio I. , Tang Xi M. , Bornman William G. , Bollag Gideon , Mills Gordon B. , Powis Garth , Desai Jayesh , Gallick Gary E. , Davies Michael A. , Kopetz Scott
Published: April 2023

PDF file - 30K, BRAF mutant cell lines utilized in the RPPA analysis. Cells were lysed at approximately 70% confluence in 10% serum. Of note, Colo201 and Colo205 are derived from the same colon cancer patient, as are HT29 and WiDr. Cell lines were obtained from the American Type Culture Collection, or the Ludwig Institute of Cancer Research. Cell line identities were confirmed by STR testing, and were verified to be Mycoplasma-free. All lines were grown in DMEM/F-12, or RPMI1640 medium supplemented with 10% FBS and 2 mmol/L glutamine or MEM, (10�S, sodium pyruvate, L-glutamine, vitamins, and nonessential amino acids). Cells were incubated in 5% CO2 at 37{degree sign}C.
Supplementary Figure 8 from MicroRNA-494 Downregulates KIT and Inhibits Gastrointestinal Stromal Tumor Cell Proliferation
Authors: Kim Won Kyu , Park Misun , Kim Young-Kook , Tae You Kwon , Yang Han-Kwang , Lee Jae Myun , Kim Hoguen
Published: April 2023

PDF file - 823K
Supplementary Figure 4 from Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents
Authors: Mao Muling , Tian Feng , Mariadason John M. , Tsao Chun C. , Lemos Robert , Dayyani Farshid , Gopal Y.N. Vashisht , Jiang Zhi-Qin , Wistuba Ignacio I. , Tang Xi M. , Bornman William G. , Bollag Gideon , Mills Gordon B. , Powis Garth , Desai Jayesh , Gallick Gary E. , Davies Michael A. , Kopetz Scott
Published: April 2023

PDF file - 44K, The combination therapy with PLX4720 and azacytidine was repeated in HT29 cells first treated with siRNA to PTEN . Silencing PTEN was not sufficient to fully abolish the synergy seen with the combination (* P<0.05).
Supplementary Figure 6 from MicroRNA-494 Downregulates KIT and Inhibits Gastrointestinal Stromal Tumor Cell Proliferation
Authors: Kim Won Kyu , Park Misun , Kim Young-Kook , Tae You Kwon , Yang Han-Kwang , Lee Jae Myun , Kim Hoguen
Published: April 2023

PDF file - 1.8MB
Supplementary Figure 4 from A Randomized Phase II Trial of Vismodegib versus Placebo with FOLFOX or FOLFIRI and Bevacizumab in Patients with Previously Untreated Metastatic Colorectal Cancer
Authors: Berlin Jordan , Bendell Johanna C. , Hart Lowell L. , Firdaus Irfan , Gore Ira , Hermann Robert C. , Mulcahy Mary F. , Zalupski Mark M. , Mackey Howard M. , Yauch Robert L. , Graham Richard A. , Bray Gordon L. , Low Jennifer A.
Published: April 2023

PDF file - 30K, Estimated maximal concentration (Cmax) and total area under the concentration-time curve (AUClast) of total and free oxaliplatin with and without vismodegib
Supplementary Table 3 from Integrative Array-Based Approach Identifies MZB1 as a Frequently Methylated Putative Tumor Suppressor in Hepatocellular Carcinoma
Authors: Matsumura Satoshi , Imoto Issei , Kozaki Ken-ichi , Matsui Takeshi , Muramatsu Tomoki , Furuta Mayuko , Tanaka Shinji , Sakamoto Michiie , Arii Shigeki , Inazawa Johji
Published: April 2023

PDF file, 55KB, Positive (methylated) and negative (unmethylated) control gene set for MeDIP-chip analysis.
Supplementary Table 1 from Mapping of Chromosome 1p Deletions in Myeloma Identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as Being Genes in Regions Associated with Adverse Survival
Authors: Boyd Kevin D. , Ross Fiona M. , Walker Brian A. , Wardell Christopher P. , Tapper William J. , Chiecchio Laura , Dagrada GianPaolo , Konn Zoe J. , Gregory Walter M. , Jackson Graham H. , Child J. Anthony , Davies Faith E. , Morgan Gareth J.
Published: April 2023

PDF file - 26KB
Supplementary Methods and Figure Legends from Integrative Array-Based Approach Identifies MZB1 as a Frequently Methylated Putative Tumor Suppressor in Hepatocellular Carcinoma
Authors: Matsumura Satoshi , Imoto Issei , Kozaki Ken-ichi , Matsui Takeshi , Muramatsu Tomoki , Furuta Mayuko , Tanaka Shinji , Sakamoto Michiie , Arii Shigeki , Inazawa Johji
Published: April 2023

PDF file, 179KB.
Supplementary Figures 1 - 4 from Integrative Array-Based Approach Identifies MZB1 as a Frequently Methylated Putative Tumor Suppressor in Hepatocellular Carcinoma
Authors: Matsumura Satoshi , Imoto Issei , Kozaki Ken-ichi , Matsui Takeshi , Muramatsu Tomoki , Furuta Mayuko , Tanaka Shinji , Sakamoto Michiie , Arii Shigeki , Inazawa Johji
Published: April 2023

PDF file, 245KB, S1 Determination of the cut-off value to accurately distinguish methylated genes in MeDIP-chip analyses.; S2 Profiles of relative expression of 11 candidates determined by quantitative real-time RT-PCR in three hepatoma cell lines (Hep3B, HepG2, and HuH-7) treated with 1, 5, and 10 μM of 5-aza-dCyd.; S3 Representative results of the methylation status of Region 3 of FAR1 CpG-island determined by COBRA (upper) and the relative expression level of FAR1 mRNA determined by quantitative real-time RT-PCR (lower) in surgically resected primary HCC tumors (T) and corresponding non-cancerous liver tissues (N).; S4 Representative results of BGS of the MZB1 CpG island (Region 1-8) in HLE cells without and with 10 μM 5-aza-dCyd.
Supplementary Tables 1 - 5 from Tumor-Associated Macrophages in Pediatric Classical Hodgkin Lymphoma: Association with Epstein-Barr Virus, Lymphocyte Subsets, and Prognostic Impact
Authors: Barros Mário Henrique M. , Hassan Rocio , Niedobitek Gerald
Published: April 2023

PDF file, 93KB, Table S1: Antibodies used for immunohistochemical staining of tissue microarray slides; Table S2: Clinical, histological and Epstein-Barr virus data at diagnosis; Table S3: Description of the macrophages, dendritic cells and lymphocytes by age-group, histological subtype and Epstein-Barr virus association in pediatric classical Hodgkin lymphoma; Table S4: Partial rank correlation controlled by age between macrophages/dendritic cells and lymphocytes from the tumor microenvironment; Table S5: Overall survival according CD163/CD8 and CD83/CD20 ratios, stratified by Epstein-Barr virus status, in pediatric classical Hodgkin lymphoma.
Supplementary Figure 2 from Tumor-Associated Macrophages in Pediatric Classical Hodgkin Lymphoma: Association with Epstein-Barr Virus, Lymphocyte Subsets, and Prognostic Impact
Authors: Barros Mário Henrique M. , Hassan Rocio , Niedobitek Gerald
Published: April 2023

PDF file, 241KB, Kaplan-Meier curves in pediatric classical Hodgkin lymphoma, according to histological subtype and age-group, stratified by EBV-association.
Related Article from BEAMing Sheds Light on Drug Resistance
Authors: Lauring Josh , Park Ben Ho
Published: April 2023

Related Article from BEAMing Sheds Light on Drug Resistance
Supplementary Table 4 from Circulating miRNAs as Surrogate Markers for Circulating Tumor Cells and Prognostic Markers in Metastatic Breast Cancer
Authors: Madhavan Dharanija , Zucknick Manuela , Wallwiener Markus , Cuk Katarina , Modugno Caroline , Scharpff Martina , Schott Sarah , Heil Jörg , Turchinovich Andrey , Yang Rongxi , Benner Axel , Riethdorf Sabine , Trumpp Andreas , Sohn Christof , Pantel Klaus , Schneeweiss Andreas , Burwinkel Barbara
Published: April 2023

XLS file, 19K, Interaction of miRNA levels and age in cases-control comparison.
Supplementary Figure 4 from Biological and Clinical Relevance of miRNA Expression Signatures in Primary Plasma Cell Leukemia
Authors: Lionetti Marta , Musto Pellegrino , Di Martino Maria Teresa , Fabris Sonia , Agnelli Luca , Todoerti Katia , Tuana Giacomo , Mosca Laura , Gallo Cantafio Maria E. , Grieco Vitina , Bianchino Gabriella , D'Auria Fiorella , Statuto Teodora , Mazzoccoli Carmela , De Luca Luciana , Petrucci Maria Teresa , Offidani Massimo , Di Raimondo Francesco , Falcone Antonietta , Caravita Tommaso , Omede' Paola , Morabito Fortunato , Tassone Pierfrancesco , Boccadoro Mario , Palumbo Antonio , Neri Antonino
Published: April 2023

PDF file - 133K, Differentially expressed miRNAs identified by supervised analysis of pPCL patients stratified according to response rate.
Supplementary Table 2 from Circulating miRNAs as Surrogate Markers for Circulating Tumor Cells and Prognostic Markers in Metastatic Breast Cancer
Authors: Madhavan Dharanija , Zucknick Manuela , Wallwiener Markus , Cuk Katarina , Modugno Caroline , Scharpff Martina , Schott Sarah , Heil Jörg , Turchinovich Andrey , Yang Rongxi , Benner Axel , Riethdorf Sabine , Trumpp Andreas , Sohn Christof , Pantel Klaus , Schneeweiss Andreas , Burwinkel Barbara
Published: April 2023

XLS file, 15K, Inter-run control variations.
Supplementary Figure 2 from Biological and Clinical Relevance of miRNA Expression Signatures in Primary Plasma Cell Leukemia
Authors: Lionetti Marta , Musto Pellegrino , Di Martino Maria Teresa , Fabris Sonia , Agnelli Luca , Todoerti Katia , Tuana Giacomo , Mosca Laura , Gallo Cantafio Maria E. , Grieco Vitina , Bianchino Gabriella , D'Auria Fiorella , Statuto Teodora , Mazzoccoli Carmela , De Luca Luciana , Petrucci Maria Teresa , Offidani Massimo , Di Raimondo Francesco , Falcone Antonietta , Caravita Tommaso , Omede' Paola , Morabito Fortunato , Tassone Pierfrancesco , Boccadoro Mario , Palumbo Antonio , Neri Antonino
Published: April 2023

PDF file - 395K, Expression plots and functional annotations charts of miRNAs identified as differentially expressed between pPCL and MM patients.
Supplementary Figure 1 from Biological and Clinical Relevance of miRNA Expression Signatures in Primary Plasma Cell Leukemia
Authors: Lionetti Marta , Musto Pellegrino , Di Martino Maria Teresa , Fabris Sonia , Agnelli Luca , Todoerti Katia , Tuana Giacomo , Mosca Laura , Gallo Cantafio Maria E. , Grieco Vitina , Bianchino Gabriella , D'Auria Fiorella , Statuto Teodora , Mazzoccoli Carmela , De Luca Luciana , Petrucci Maria Teresa , Offidani Massimo , Di Raimondo Francesco , Falcone Antonietta , Caravita Tommaso , Omede' Paola , Morabito Fortunato , Tassone Pierfrancesco , Boccadoro Mario , Palumbo Antonio , Neri Antonino
Published: April 2023

PDF file - 358K, MiRNA expression profiles in pPCL patients.
Supplementary Figure 1 from Circulating miRNAs as Surrogate Markers for Circulating Tumor Cells and Prognostic Markers in Metastatic Breast Cancer
Authors: Madhavan Dharanija , Zucknick Manuela , Wallwiener Markus , Cuk Katarina , Modugno Caroline , Scharpff Martina , Schott Sarah , Heil Jörg , Turchinovich Andrey , Yang Rongxi , Benner Axel , Riethdorf Sabine , Trumpp Andreas , Sohn Christof , Pantel Klaus , Schneeweiss Andreas , Burwinkel Barbara
Published: April 2023

PDF file, 490K, Clustering of samples.
Supplementary Figure 6 from The Effects of Chemotherapy on Cognitive Function in a Mouse Model: A Prospective Study
Authors: Winocur Gordon , Henkelman Mark , Wojtowicz J. Martin , Zhang Haibo , Binns Malcolm A. , Tannock Ian F.
Published: April 2023

PDF file, 300KB, Figure S6. Comparison of the CHEMO and SAL groups averaged anatomical brain MRI scans after treatment and behavioral testing. There are no visible differences and none identified by statistical analysis.
Supplementary Figure 1 from A Functional Variant at 19q13.3, rs967591G>A, Is Associated with Shorter Survival of Early-Stage Lung Cancer
Authors: Jeon Hyo-Sung , Jin Guang , Kang Hyo-Gyoung , Choi Yi Young , Lee Won Kee , Choi Jin Eun , Bae Eun Young , Yoo Seung Soo , Lee Shin Yup , Lee Eung Bae , Kim Young Tae , Lee Jaehee , Cha Seung-Ick , Kim Chang Ho , Jheon Sanghoon , Kim In San , Park Jae Yong
Published: April 2023

PDF file - 92K, Kaplan-Meier plot of overall survival according to the rs1005165C>T (A), rs967591G>A (B) rs735482A>C (C), rs3212986G>T (D) and rs11615G>A (E) genotypes in the stage I study, and the rs967591G>A (F) genotypes in the stage 2 validation study. P-values, Log-Rank test (*P-values in A, B, C and F: in recessive models for the variant allele).
Supplementary Figure 2 from The Effects of Chemotherapy on Cognitive Function in a Mouse Model: A Prospective Study
Authors: Winocur Gordon , Henkelman Mark , Wojtowicz J. Martin , Zhang Haibo , Binns Malcolm A. , Tannock Ian F.
Published: April 2023

PDF file, 20KB, Figure S2. Performance of CHEMO and SAL groups on the spatial memory test administered at baseline. Errors represent the mean number of errors /day in finding the submerged platform over 5 days of testing. (Error bars denote � SEM)
Supplementary Table 6A from AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
Authors: Yap Timothy A. , Walton Mike I. , Grimshaw Kyla M. , te Poele Robert H. , Eve Paul D. , Valenti Melanie R. , de Haven Brandon Alexis K. , Martins Vanessa , Zetterlund Anna , Heaton Simon P. , Heinzmann Kathrin , Jones Paul S. , Feltell Ruth E. , Reule Matthias , Woodhead Steven J. , Davies Thomas G. , Lyons John F. , Raynaud Florence I. , Eccles Suzanne A. , Workman Paul , Thompson Neil T. , Garrett Michelle D.
Published: April 2023

XLS file - 66K, Genes that showed at least a 1.5 Fold Change in at least one treated sample compared to vehicle control and were differentially expressed between the treatment groups (Welch ANOVA FDR5%) for both CCT128930 and AT13148
Supplementary Figures 1-3 from BCL2 Predicts Survival in Germinal Center B-cell–like Diffuse Large B-cell Lymphoma Treated with CHOP-like Therapy and Rituximab
Authors: Iqbal Javeed , Meyer Paul N. , Smith Lynette M. , Johnson Nathalie A. , Vose Julie M. , Greiner Timothy C. , Connors Joseph M. , Staudt Louis M. , Rimsza Lisa , Jaffe Elaine , Rosenwald Andreas , Ott German , Delabie Jan , Campo Elias , Braziel Rita M. , Cook James R. , Tubbs Raymond R. , Gascoyne Randy D. , Armitage James O. , Weisenburger Dennis D. , Chan Wing C.
Published: April 2023

PDF file - 106K
Supplementary Figure Legends 1-3, Tables 1-3 from BCL2 Predicts Survival in Germinal Center B-cell–like Diffuse Large B-cell Lymphoma Treated with CHOP-like Therapy and Rituximab
Authors: Iqbal Javeed , Meyer Paul N. , Smith Lynette M. , Johnson Nathalie A. , Vose Julie M. , Greiner Timothy C. , Connors Joseph M. , Staudt Louis M. , Rimsza Lisa , Jaffe Elaine , Rosenwald Andreas , Ott German , Delabie Jan , Campo Elias , Braziel Rita M. , Cook James R. , Tubbs Raymond R. , Gascoyne Randy D. , Armitage James O. , Weisenburger Dennis D. , Chan Wing C.
Published: April 2023

PDF file - 134K
Supplementary Figures 1-7, Tables 1-4 from AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
Authors: Yap Timothy A. , Walton Mike I. , Grimshaw Kyla M. , te Poele Robert H. , Eve Paul D. , Valenti Melanie R. , de Haven Brandon Alexis K. , Martins Vanessa , Zetterlund Anna , Heaton Simon P. , Heinzmann Kathrin , Jones Paul S. , Feltell Ruth E. , Reule Matthias , Woodhead Steven J. , Davies Thomas G. , Lyons John F. , Raynaud Florence I. , Eccles Suzanne A. , Workman Paul , Thompson Neil T. , Garrett Michelle D.
Published: April 2023

PDF file - 553K, Supplementary Figure 1. Phosphorylation of AKT substrates remains suppressed, despite pSer473 AKT induction. Supplementary Figure 2. The pharmacokinetic-pharmacodynamic profile and antitumor activity of AT13148 in PTEN-deficient PC3 human prostate cancer xenografts. Supplementary Figure 3. Pharmacodynamic biomarker study of AT13148(40mg/kg) in MES-SA human tumor xenografts. Supplementary Figure 4. The antitumour activity of AT13148 in mutant KRAS A549 human lung cancer xenografts. Supplementary Figure 5. Mouse body weight data for the MES-SA (Figure 4B) and BT474 (Figure 4C) efficacy studies. Supplementary Figure 6. The effect of AT13148 versus CCT128930 on apoptosis and cell cycle distribution in U87MG human glioblastoma cells. Supplementary Figure 7. Differential effects of 24h treatment of 10M each of the AGC kinase inhibitor AT13148 and the selective AKT inhibitor CCT128930 on cell cycle effects in PTEN-deficient U87MG human glioblastoma cells. Supplementary Table 1. Summary of the inhibitory activity of 10��M AT13148 against in vitro. Supplementary Table 2. Summary of the inhibitory activity of AT13148 against a panel of protein kinases Supplementary Table 3. Summary of the in vitro cytotoxicity of AT13148 against a panel of human tumor cell lines harboring different defects in the PI3K-AKT signaling pathway. Supplementary Table 4. Summary of the pharmacokinetics of AT13148 in mouse plasma and tissues following iv or oral administration
Supplementary Table 1 from Large-scale Analysis of PDGFRA Mutations in Melanomas and Evaluation of Their Sensitivity to Tyrosine Kinase Inhibitors Imatinib and Crenolanib
Authors: Dai Jie , Kong Yan , Si Lu , Chi Zhihong , Cui Chuanliang , Sheng Xinan , Mao Lili , Li Siming , Lian Bin , Yang Ruifeng , Liu Shujing , Xu Xiaowei , Guo Jun
Published: April 2023

PDF file - 121K, Supplementary Table S1. Primers and annealing temperatures for the sequencing of PDGFRA.
Supplementary Methods and Tables from Loss of NAPRT1 Expression by Tumor-Specific Promoter Methylation Provides a Novel Predictive Biomarker for NAMPT Inhibitors
Authors: Shames David S. , Elkins Kristi , Walter Kimberly , Holcomb Thomas , Du Pan , Mohl Dane , Xiao Yang , Pham Thinh , Haverty Peter M. , Liederer Bianca , Liang Xiaorong , Yauch Robert L. , O'Brien Thomas , Bourgon Richard , Koeppen Hartmut , Belmont Lisa D.
Published: April 2023

PDF file 141K, Supplementary methods for NAD quantification and the QMSP assay. Table S1 GNE-617 IC50 and mRNA Levels of NAMPT and NAPRT1, Table S2 Cell Lines Not Rescued with 10uM NA, Table S3 Cell Lines with Low NAPRT1 Expression
Supplementary Figure 4 from Large-scale Analysis of PDGFRA Mutations in Melanomas and Evaluation of Their Sensitivity to Tyrosine Kinase Inhibitors Imatinib and Crenolanib
Authors: Dai Jie , Kong Yan , Si Lu , Chi Zhihong , Cui Chuanliang , Sheng Xinan , Mao Lili , Li Siming , Lian Bin , Yang Ruifeng , Liu Shujing , Xu Xiaowei , Guo Jun
Published: April 2023

PDF file - 373K, Figure S4. Effects of imatinib and crenolanib on activation of mutational PDGFRA.
Supplementary Figure 1 from Large-scale Analysis of PDGFRA Mutations in Melanomas and Evaluation of Their Sensitivity to Tyrosine Kinase Inhibitors Imatinib and Crenolanib
Authors: Dai Jie , Kong Yan , Si Lu , Chi Zhihong , Cui Chuanliang , Sheng Xinan , Mao Lili , Li Siming , Lian Bin , Yang Ruifeng , Liu Shujing , Xu Xiaowei , Guo Jun
Published: April 2023

PDF file - 1363K, Figure S1. Genetic mutations in exon 12 of PDGFRA.
Supplementary Figure 2 from Skin Tumors Induced by Sorafenib; Paradoxic RAS–RAF Pathway Activation and Oncogenic Mutations of HRAS, TP53, and TGFBR1
Authors: Arnault Jean Philippe , Mateus Christine , Escudier Bernard , Tomasic Gorana , Wechsler Janine , Hollville Emilie , Soria Jean-Charles , Malka David , Sarasin Alain , Larcher Magalie , André Jocelyne , Kamsu-Kom Nyam , Boussemart Lise , Lacroix Ludovic , Spatz Alain , Eggermont Alexander M. , Druillennec Sabine , Vagner Stephan , Eychène Alain , Dumaz Nicolas , Robert Caroline
Published: April 2023

PDF file - 1.4MB
Supplementary Figure 1 from Skin Tumors Induced by Sorafenib; Paradoxic RAS–RAF Pathway Activation and Oncogenic Mutations of HRAS, TP53, and TGFBR1
Authors: Arnault Jean Philippe , Mateus Christine , Escudier Bernard , Tomasic Gorana , Wechsler Janine , Hollville Emilie , Soria Jean-Charles , Malka David , Sarasin Alain , Larcher Magalie , André Jocelyne , Kamsu-Kom Nyam , Boussemart Lise , Lacroix Ludovic , Spatz Alain , Eggermont Alexander M. , Druillennec Sabine , Vagner Stephan , Eychène Alain , Dumaz Nicolas , Robert Caroline
Published: April 2023

PDF file - 208K
Supplementary Data from The Telomerase Antagonist, Imetelstat, Efficiently Targets Glioblastoma Tumor-Initiating Cells Leading to Decreased Proliferation and Tumor Growth
Authors: Marian Calin O. , Cho Steve K. , Mcellin Brian M. , Maher Elizabeth A. , Hatanpaa Kimmo J. , Madden Christopher J. , Mickey Bruce E. , Wright Woodring E. , Shay Jerry W. , Bachoo Robert M.
Published: April 2023

Supplementary Data from The Telomerase Antagonist, Imetelstat, Efficiently Targets Glioblastoma Tumor-Initiating Cells Leading to Decreased Proliferation and Tumor Growth
Supplementary Figure 6 from Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
Authors: Zhong Cuiling , Wang Jianyong , Li Bing , Xiang Hong , Ultsch Mark , Coons Mary , Wong Terence , Chiang Nancy Y. , Clark Suzy , Clark Robyn , Quintana Leah , Gribling Peter , Suto Eric , Barck Kai , Corpuz Racquel , Yao Jenny , Takkar Rashi , Lee Wyne P. , Damico-Beyer Lisa A. , Carano Richard D. , Adams Camellia , Kelley Robert F. , Wang Weiru , Ferrara Napoleone
Published: April 2023

PDF file, 26K, Comparison of PK in Balb c/nude mice of three hamster antibodies with similar binding affinity toward human CXCL12.
Information of Microarray Data from Differential Response to Neoadjuvant Chemotherapy Among 7 Triple-Negative Breast Cancer Molecular Subtypes
Authors: Masuda Hiroko , Baggerly Keith A. , Wang Ying , Zhang Ya , Gonzalez-Angulo Ana Maria , Meric-Bernstam Funda , Valero Vicente , Lehmann Brian D. , Pietenpol Jennifer A. , Hortobagyi Gabriel N. , Symmans W. Fraser , Ueno Naoto T.
Published: April 2023

Information of Microarray Data - PDF file 31K, Gene expression data have been deposited into the GEO database
Supplementary Figure 5 from Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
Authors: Zhong Cuiling , Wang Jianyong , Li Bing , Xiang Hong , Ultsch Mark , Coons Mary , Wong Terence , Chiang Nancy Y. , Clark Suzy , Clark Robyn , Quintana Leah , Gribling Peter , Suto Eric , Barck Kai , Corpuz Racquel , Yao Jenny , Takkar Rashi , Lee Wyne P. , Damico-Beyer Lisa A. , Carano Richard D. , Adams Camellia , Kelley Robert F. , Wang Weiru , Ferrara Napoleone
Published: April 2023

PDF file, 28K, Effects of 30D8 on CXCL12 and VEGF serum levels in HM7 tumor bearing mice.
CCR Translation for This Article from Quantitative Detection of EGFR Mutations in Circulating Tumor DNA Derived from Lung Adenocarcinomas
Authors: Taniguchi Kazuya , Uchida Junji , Nishino Kazumi , Kumagai Toru , Okuyama Takako , Okami Jiro , Higashiyama Masahiko , Kodama Ken , Imamura Fumio , Kato Kikuya
Published: April 2023

CCR Translation for This Article from Quantitative Detection of EGFR Mutations in Circulating Tumor DNA Derived from Lung Adenocarcinomas
Supplementary Figure 4 from Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
Authors: Zhong Cuiling , Wang Jianyong , Li Bing , Xiang Hong , Ultsch Mark , Coons Mary , Wong Terence , Chiang Nancy Y. , Clark Suzy , Clark Robyn , Quintana Leah , Gribling Peter , Suto Eric , Barck Kai , Corpuz Racquel , Yao Jenny , Takkar Rashi , Lee Wyne P. , Damico-Beyer Lisa A. , Carano Richard D. , Adams Camellia , Kelley Robert F. , Wang Weiru , Ferrara Napoleone
Published: April 2023

PDF file, 38K, Sequence alignment of 30D8 and humanized 30D8 (hu30D8).
Supplementary Table 3 from Increased miR-708 Expression in NSCLC and Its Association with Poor Survival in Lung Adenocarcinoma from Never Smokers
Authors: Jang Jin Sung , Jeon Hyo-Sung , Sun Zhifu , Aubry Marie Christine , Tang Hui , Park Cheol-Hong , Rakhshan Fariborz , Schultz Debra A. , Kolbert Christopher P. , Lupu Ruth , Park Jae Yong , Harris Curtis C. , Yang Ping , Jen Jin
Published: April 2023

PDF file, 58KB, Potential Target Genes of miR-708.
Supplementary Figure 2 from Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
Authors: Zhong Cuiling , Wang Jianyong , Li Bing , Xiang Hong , Ultsch Mark , Coons Mary , Wong Terence , Chiang Nancy Y. , Clark Suzy , Clark Robyn , Quintana Leah , Gribling Peter , Suto Eric , Barck Kai , Corpuz Racquel , Yao Jenny , Takkar Rashi , Lee Wyne P. , Damico-Beyer Lisa A. , Carano Richard D. , Adams Camellia , Kelley Robert F. , Wang Weiru , Ferrara Napoleone
Published: April 2023

PDF file, 20K, Effects of 30D8 on 4T1 cell migration in vitro.
Supplementary Figure 1 from Development and Preclinical Characterization of a Humanized Antibody Targeting CXCL12
Authors: Zhong Cuiling , Wang Jianyong , Li Bing , Xiang Hong , Ultsch Mark , Coons Mary , Wong Terence , Chiang Nancy Y. , Clark Suzy , Clark Robyn , Quintana Leah , Gribling Peter , Suto Eric , Barck Kai , Corpuz Racquel , Yao Jenny , Takkar Rashi , Lee Wyne P. , Damico-Beyer Lisa A. , Carano Richard D. , Adams Camellia , Kelley Robert F. , Wang Weiru , Ferrara Napoleone
Published: April 2023

PDF file, 869K, Proliferation and apoptosis analysis by IF staining in EL4 tumor sections.
Supplementary Table 1 from Increased miR-708 Expression in NSCLC and Its Association with Poor Survival in Lung Adenocarcinoma from Never Smokers
Authors: Jang Jin Sung , Jeon Hyo-Sung , Sun Zhifu , Aubry Marie Christine , Tang Hui , Park Cheol-Hong , Rakhshan Fariborz , Schultz Debra A. , Kolbert Christopher P. , Lupu Ruth , Park Jae Yong , Harris Curtis C. , Yang Ping , Jen Jin
Published: April 2023

PDF file, 69KB, Clinical Information of the three lung adenocarcinoma Cohorts.
Supplementary Table 2 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models
Authors: Rosa Roberta , Marciano Roberta , Malapelle Umberto , Formisano Luigi , Nappi Lucia , D'Amato Claudia , D'Amato Valentina , Damiano Vincenzo , Marfè Gabriella , Del Vecchio Silvana , Zannetti Antonella , Greco Adelaide , De Stefano Alfonso , Carlomagno Chiara , Veneziani Bianca Maria , Troncone Giancarlo , De Placido Sabino , Bianco Roberto
Published: April 2023

PDF file - 908K, Multivariate analysis correlating the response to cetuximab-based regimens to different factors
Supplementary Table 1 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models
Authors: Rosa Roberta , Marciano Roberta , Malapelle Umberto , Formisano Luigi , Nappi Lucia , D'Amato Claudia , D'Amato Valentina , Damiano Vincenzo , Marfè Gabriella , Del Vecchio Silvana , Zannetti Antonella , Greco Adelaide , De Stefano Alfonso , Carlomagno Chiara , Veneziani Bianca Maria , Troncone Giancarlo , De Placido Sabino , Bianco Roberto
Published: April 2023

PDF file - 427K, Effects of the combination cetuximab plus fingolimod on tumor growth of mice xenografted with GEO-CR resistant tumors
Supplementary Methods from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models
Authors: Rosa Roberta , Marciano Roberta , Malapelle Umberto , Formisano Luigi , Nappi Lucia , D'Amato Claudia , D'Amato Valentina , Damiano Vincenzo , Marfè Gabriella , Del Vecchio Silvana , Zannetti Antonella , Greco Adelaide , De Stefano Alfonso , Carlomagno Chiara , Veneziani Bianca Maria , Troncone Giancarlo , De Placido Sabino , Bianco Roberto
Published: April 2023

PDF file - 39K
Supplementary Figure 1 from Increased miR-708 Expression in NSCLC and Its Association with Poor Survival in Lung Adenocarcinoma from Never Smokers
Authors: Jang Jin Sung , Jeon Hyo-Sung , Sun Zhifu , Aubry Marie Christine , Tang Hui , Park Cheol-Hong , Rakhshan Fariborz , Schultz Debra A. , Kolbert Christopher P. , Lupu Ruth , Park Jae Yong , Harris Curtis C. , Yang Ping , Jen Jin
Published: April 2023

PDF file, 147KB, Validation of miR-708 Overexpression by Real-Time qPCR in Lung Squamous cell carcinoma. Non-paired mostly smoker Squamous cell carcinomas and normal FFPE tissues from the National Cancer Institute cohort were examined. Sample numbers (n) and tissue types are indicated on each graph. P values are as shown by unpaired 2-tailed t test.
Supplementary Figure Legend from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models
Authors: Rosa Roberta , Marciano Roberta , Malapelle Umberto , Formisano Luigi , Nappi Lucia , D'Amato Claudia , D'Amato Valentina , Damiano Vincenzo , Marfè Gabriella , Del Vecchio Silvana , Zannetti Antonella , Greco Adelaide , De Stefano Alfonso , Carlomagno Chiara , Veneziani Bianca Maria , Troncone Giancarlo , De Placido Sabino , Bianco Roberto
Published: April 2023

PDF file - 32K
Supplementary Figure 5 from Predictive Biomarkers of Sensitivity to the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Preclinical Breast Cancer Models
Authors: Diamond Jennifer R. , Eckhardt S. Gail , Tan Aik Choon , Newton Timothy P. , Selby Heather M. , Brunkow Kelsey L. , Kachaeva Maria I. , Varella-Garcia Marileila , Pitts Todd M. , Bray Mark R. , Fletcher Graham C. , Tentler John J.
Published: April 2023

PDF file - 247K, Heatmap for the two most sensitive versus the two most resistant TNBC cell lines and Gene Set Enrichment Analysis (GSEA) of ENMD-2076 sensitivity
Supplementary Figure 5 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models
Authors: Rosa Roberta , Marciano Roberta , Malapelle Umberto , Formisano Luigi , Nappi Lucia , D'Amato Claudia , D'Amato Valentina , Damiano Vincenzo , Marfè Gabriella , Del Vecchio Silvana , Zannetti Antonella , Greco Adelaide , De Stefano Alfonso , Carlomagno Chiara , Veneziani Bianca Maria , Troncone Giancarlo , De Placido Sabino , Bianco Roberto
Published: April 2023

PDF file - 5320K, Validation of antibodies for analysis of SphK1 expression on FFPE colorectal cancer tissues
Supplementary Figure 4 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models
Authors: Rosa Roberta , Marciano Roberta , Malapelle Umberto , Formisano Luigi , Nappi Lucia , D'Amato Claudia , D'Amato Valentina , Damiano Vincenzo , Marfè Gabriella , Del Vecchio Silvana , Zannetti Antonella , Greco Adelaide , De Stefano Alfonso , Carlomagno Chiara , Veneziani Bianca Maria , Troncone Giancarlo , De Placido Sabino , Bianco Roberto
Published: April 2023

PDF file - 1047K, Effects of the combination cetuximab plus fingolimod on apoptosis of GEO-CR tumor xenografts
Supplementary Figure 3 from Predictive Biomarkers of Sensitivity to the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Preclinical Breast Cancer Models
Authors: Diamond Jennifer R. , Eckhardt S. Gail , Tan Aik Choon , Newton Timothy P. , Selby Heather M. , Brunkow Kelsey L. , Kachaeva Maria I. , Varella-Garcia Marileila , Pitts Todd M. , Bray Mark R. , Fletcher Graham C. , Tentler John J.
Published: April 2023

PDF file - 121K, Heatmap of the 580 differentially expressed genes between ENMD-2076-sensitive and -resistant cell lines as identified by the Significance Analysis of Microarrays (SAM) with FD
Supplementary Figure 3 from Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models
Authors: Rosa Roberta , Marciano Roberta , Malapelle Umberto , Formisano Luigi , Nappi Lucia , D'Amato Claudia , D'Amato Valentina , Damiano Vincenzo , Marfè Gabriella , Del Vecchio Silvana , Zannetti Antonella , Greco Adelaide , De Stefano Alfonso , Carlomagno Chiara , Veneziani Bianca Maria , Troncone Giancarlo , De Placido Sabino , Bianco Roberto
Published: April 2023

PDF file - 503K, Effects of SphK1 modulation on cetuximab sensitivity in resistant colorectal cancer cell lines
Supplementary Figure legend from Weekly nab-Rapamycin in Patients with Advanced Nonhematologic Malignancies: Final Results of a Phase I Trial
Authors: Gonzalez-Angulo Ana M. , Meric-Bernstam Funda , Chawla Sant , Falchook Gerald , Hong David , Akcakanat Argun , Chen Huiqin , Naing Aung , Fu Siqing , Wheler Jennifer , Moulder Stacy , Helgason Thorunn , Li Shaoyi , Elias Ileana , Desai Neil , Kurzrock Razelle
Published: April 2023

Supplementary Figure legend
Supplementary Methods, Tables 1-5, Figures 1-6 from The 2-Nitroimidazole EF5 Is a Biomarker for Oxidoreductases That Activate the Bioreductive Prodrug CEN-209 under Hypoxia
Authors: Wang Jingli , Foehrenbacher Annika , Su Jiechuang , Patel Rita , Hay Michael P. , Hicks Kevin O. , Wilson William R.
Published: April 2023

PDF file - 370K
CCR Translation for This Article from The 2-Nitroimidazole EF5 Is a Biomarker for Oxidoreductases That Activate the Bioreductive Prodrug CEN-209 under Hypoxia
Authors: Wang Jingli , Foehrenbacher Annika , Su Jiechuang , Patel Rita , Hay Michael P. , Hicks Kevin O. , Wilson William R.
Published: April 2023

CCR Translation for This Article from The 2-Nitroimidazole EF5 Is a Biomarker for Oxidoreductases That Activate the Bioreductive Prodrug CEN-209 under Hypoxia
Supplementary Fig 1 from Weekly nab-Rapamycin in Patients with Advanced Nonhematologic Malignancies: Final Results of a Phase I Trial
Authors: Gonzalez-Angulo Ana M. , Meric-Bernstam Funda , Chawla Sant , Falchook Gerald , Hong David , Akcakanat Argun , Chen Huiqin , Naing Aung , Fu Siqing , Wheler Jennifer , Moulder Stacy , Helgason Thorunn , Li Shaoyi , Elias Ileana , Desai Neil , Kurzrock Razelle
Published: April 2023

Mesothelioma patient molecular profile from biopsy: A) Immunohistochemical staining of phosphatase and tensin homolog (PTEN); B) Single-nucleotide polymorphism on PH domain leucine-rich repeat protein phosphatase 2 (PHLPP2)
Supplementary Table 1 from Src Inhibition with Saracatinib Reverses Fulvestrant Resistance in ER-Positive Ovarian Cancer Models In Vitro and In Vivo
Authors: Simpkins Fiona , Hevia-Paez Pedro , Sun Jun , Ullmer Wendy , Gilbert Candace A. , da Silva Thiago , Pedram Ali , Levin Ellis R. , Reis Isildinha M. , Rabinovich Brian , Azzam Diana , Xu Xiang-Xi , Ince Tan A. , Yang Ji-Yeon , Verhaak Roel G.W. , Lu Yiling , Mills Gordon B. , Slingerland Joyce M.
Published: April 2023

PDF file, 46K, List of genes which have one or more ERE in the promoter upstream 10kb region in 111 genes that overlapped in the High ERα and High p416Src groups.
Data Supplement from Evidence for Molecular Differences in Prostate Cancer between African American and Caucasian Men
Authors: Khani Francesca , Mosquera Juan Miguel , Park Kyung , Blattner Mirjam , O'Reilly Catherine , MacDonald Theresa Y. , Chen Zhengming , Srivastava Abhishek , Tewari Ashutosh K. , Barbieri Christopher E. , Rubin Mark A. , Robinson Brian D.
Published: April 2023

Supplemental Figure S1: Heat Map of All Molecular Alterations Observed in Each Cohort.
Data Supplement from Evidence for Molecular Differences in Prostate Cancer between African American and Caucasian Men
Authors: Khani Francesca , Mosquera Juan Miguel , Park Kyung , Blattner Mirjam , O'Reilly Catherine , MacDonald Theresa Y. , Chen Zhengming , Srivastava Abhishek , Tewari Ashutosh K. , Barbieri Christopher E. , Rubin Mark A. , Robinson Brian D.
Published: April 2023

Supplementary Figure Legend
Supplementary Table 1 from A Phase I Single-Agent Study of Twice-Weekly Consecutive-Day Dosing of the Proteasome Inhibitor Carfilzomib in Patients with Relapsed or Refractory Multiple Myeloma or Lymphoma
Authors: Alsina Melissa , Trudel Suzanne , Furman Richard R. , Rosen Peter J. , O'Connor Owen A. , Comenzo Raymond L. , Wong Alvin , Kunkel Lori A. , Molineaux Christopher J. , Goy Andre
Published: April 2023

PDF file, 79K, Treatment-emergent Adverse Events, Regardless of Relationship to Carfilzomib Treatment, Reported in ≥10% but <20% of Patients or Related to Carfilzomib Occurring in ≥5% of Patients.
Supplementary Table 1 from Interleukin 15 Provides Relief to CTLs from Regulatory T Cell–Mediated Inhibition: Implications for Adoptive T Cell–Based Therapies for Lymphoma
Authors: Perna Serena K. , De Angelis Biagio , Pagliara Daria , Hasan Sayyeda T. , Zhang Lan , Mahendravada Aruna , Heslop Helen E. , Brenner Malcolm K. , Rooney Cliona M. , Dotti Gianpietro , Savoldo Barbara
Published: April 2023

PDF file - 55K, Suppl. Table 1. Recovery of Tregs from healthy donors and from HL patients
Data Supplement from Influence of Biospecimen Variables on Proteomic Biomarkers in Breast Cancer
Authors: Meric-Bernstam Funda , Akcakanat Argun , Chen Huiqin , Sahin Aysegul , Tarco Emily , Carkaci Selin , Adrada Beatriz E. , Singh Gopal , Do Kim-Anh , Garces Zerzhinski M. , Mittendorf Elizabeth , Babiera Gildy , Bedrosian Isabelle , Hwang Rosa , Krishnamurthy Savitri , Symmans William F. , Gonzalez-Angulo Ana Maria , Mills Gordon B.
Published: April 2023

Supplementary Table 1. Biopsies acquired in each patient
Data Supplement from Influence of Biospecimen Variables on Proteomic Biomarkers in Breast Cancer
Authors: Meric-Bernstam Funda , Akcakanat Argun , Chen Huiqin , Sahin Aysegul , Tarco Emily , Carkaci Selin , Adrada Beatriz E. , Singh Gopal , Do Kim-Anh , Garces Zerzhinski M. , Mittendorf Elizabeth , Babiera Gildy , Bedrosian Isabelle , Hwang Rosa , Krishnamurthy Savitri , Symmans William F. , Gonzalez-Angulo Ana Maria , Mills Gordon B.
Published: April 2023

Supplementary Table 2. Antibodies used in RPPA
Supplementary Table 1 from Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells
Authors: Koochekpour Shahriar , Majumdar Sunipa , Azabdaftari Gissou , Attwood Kristopher , Scioneaux Ray , Subramani Dhatchayini , Manhardt Charles , Lorusso Giovanni D. , Willard Stacey S. , Thompson Hillary , Shourideh Mojgan , Rezaei Katayoon , Sartor Oliver , Mohler James L. , Vessella Robert L.
Published: April 2023

PDF file - 66K, Descriptives of the study cohort used for serum glutamate quantification
Data Supplement from Influence of Biospecimen Variables on Proteomic Biomarkers in Breast Cancer
Authors: Meric-Bernstam Funda , Akcakanat Argun , Chen Huiqin , Sahin Aysegul , Tarco Emily , Carkaci Selin , Adrada Beatriz E. , Singh Gopal , Do Kim-Anh , Garces Zerzhinski M. , Mittendorf Elizabeth , Babiera Gildy , Bedrosian Isabelle , Hwang Rosa , Krishnamurthy Savitri , Symmans William F. , Gonzalez-Angulo Ana Maria , Mills Gordon B.
Published: April 2023

Supplementary Table 5: The tumor cellularity of each biospecimen as assessed by H&E Supplementary Table 6: Correlation of protein expression by RPPA between different biospecimens (Spearman's correlation). Analysis was conducted in samples with ï‚³20% cellularity as well as in all samples separately. Supplementary Table 7: Comparison of protein expression by RPPA between different biospecimens (Student's t-test) Supplementary Table 8: Correlation of biomarker expression by RPPA between CNB, central and peripheral samples based on biospecimen variables Supplementary Table 9: Correlation of biomarker expression by RPPA and tumor cellularity in CNB, central and peripheral samples. Analysis was conducted in samples with ï‚³20% cellularity as well as in all samples separately. Supplementary Table 10: Correlation of biomarker expression by RPPA in CNB and FNA with central and peripheral samples based on whether neoadjuvant chemotherapy had been administered.
Supplementary Figure Legend from Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells
Authors: Koochekpour Shahriar , Majumdar Sunipa , Azabdaftari Gissou , Attwood Kristopher , Scioneaux Ray , Subramani Dhatchayini , Manhardt Charles , Lorusso Giovanni D. , Willard Stacey S. , Thompson Hillary , Shourideh Mojgan , Rezaei Katayoon , Sartor Oliver , Mohler James L. , Vessella Robert L.
Published: April 2023

PDF file - 83K
Data Supplement from Influence of Biospecimen Variables on Proteomic Biomarkers in Breast Cancer
Authors: Meric-Bernstam Funda , Akcakanat Argun , Chen Huiqin , Sahin Aysegul , Tarco Emily , Carkaci Selin , Adrada Beatriz E. , Singh Gopal , Do Kim-Anh , Garces Zerzhinski M. , Mittendorf Elizabeth , Babiera Gildy , Bedrosian Isabelle , Hwang Rosa , Krishnamurthy Savitri , Symmans William F. , Gonzalez-Angulo Ana Maria , Mills Gordon B.
Published: April 2023

Supplementary Table 11. Comparison of the correlation of biomarker expression by RPPA in CNB and FNA with central and peripheral samples based on whether neoadjuvant chemotherapy had been administered.
Supplementary Figure 4 from Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells
Authors: Koochekpour Shahriar , Majumdar Sunipa , Azabdaftari Gissou , Attwood Kristopher , Scioneaux Ray , Subramani Dhatchayini , Manhardt Charles , Lorusso Giovanni D. , Willard Stacey S. , Thompson Hillary , Shourideh Mojgan , Rezaei Katayoon , Sartor Oliver , Mohler James L. , Vessella Robert L.
Published: April 2023

PDF file - 34K, Effect of BAY36-7620 on prostate cancer cells proliferation
Supplementary Methods from Noninvasive Detection of HER2 Amplification with Plasma DNA Digital PCR
Authors: Gevensleben Heidrun , Garcia-Murillas Isaac , Graeser Monika K. , Schiavon Gaia , Osin Peter , Parton Marina , Smith Ian E. , Ashworth Alan , Turner Nicholas C.
Published: April 2023

PDF File - 177K, Supplementary methods, tables, and figures legends.
Supplementary Figure 3 from Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells
Authors: Koochekpour Shahriar , Majumdar Sunipa , Azabdaftari Gissou , Attwood Kristopher , Scioneaux Ray , Subramani Dhatchayini , Manhardt Charles , Lorusso Giovanni D. , Willard Stacey S. , Thompson Hillary , Shourideh Mojgan , Rezaei Katayoon , Sartor Oliver , Mohler James L. , Vessella Robert L.
Published: April 2023

PDF file - 80K, Immunohistochemical staining of metabotropic glutamate receptor 1 (GRM1) in selected prostate cancers
Supplementary Figure 6 from Noninvasive Detection of HER2 Amplification with Plasma DNA Digital PCR
Authors: Gevensleben Heidrun , Garcia-Murillas Isaac , Graeser Monika K. , Schiavon Gaia , Osin Peter , Parton Marina , Smith Ian E. , Ashworth Alan , Turner Nicholas C.
Published: April 2023

PDF File - 694K, Comparison between EFTUD2 and UBBP4 reference probes on patient plasma samples.
Supplementary Figure 5 from Noninvasive Detection of HER2 Amplification with Plasma DNA Digital PCR
Authors: Gevensleben Heidrun , Garcia-Murillas Isaac , Graeser Monika K. , Schiavon Gaia , Osin Peter , Parton Marina , Smith Ian E. , Ashworth Alan , Turner Nicholas C.
Published: April 2023

PDF File - 883K, Bio-informatic comparison of different reference probes.
Supplementary Figure 4 from Noninvasive Detection of HER2 Amplification with Plasma DNA Digital PCR
Authors: Gevensleben Heidrun , Garcia-Murillas Isaac , Graeser Monika K. , Schiavon Gaia , Osin Peter , Parton Marina , Smith Ian E. , Ashworth Alan , Turner Nicholas C.
Published: April 2023

PDF File - 438K, HER2 : EFTUD2 copy number ratio in validation cohort.
Supplementary Figure 3 from Noninvasive Detection of HER2 Amplification with Plasma DNA Digital PCR
Authors: Gevensleben Heidrun , Garcia-Murillas Isaac , Graeser Monika K. , Schiavon Gaia , Osin Peter , Parton Marina , Smith Ian E. , Ashworth Alan , Turner Nicholas C.
Published: April 2023

PDF File - 854K, Digital PCR analysis by droplet digital PCR.
Supplementary Tables 1 - 9 from The Critical Role of Dysregulated FOXM1–PLAUR Signaling in Human Colon Cancer Progression and Metastasis
Authors: Li Dawei , Wei Ping , Peng Zhihai , Huang Chen , Tang Huamei , Jia Zhiliang , Cui Jiujie , Le Xiangdong , Huang Suyun , Xie Keping
Published: April 2023

PDF file - 113K, Table S1. Different FOXM1 protein expressions in primary colon cancer and matched lymph node metastasis; Table S2. FOXM1 expression and clinicopathologic characteristics; Table S3. Correlation of FOXM1 expression with metastasis of colon cancer patients after radical colectomy (n = 185); Table S4. Multivariate analyses of overall survival and metastasis free survival of colon cancer patients; Table S5. Different PLAUR protein expressions in primary colon cancer and matched lymph node metastasis; Table S6. PLAUR expression and clinicopathologic characteristics; Table S7. Multivariate analyses of overall survival and metastasis free survival of colon cancer patients; Table S8. Correlation of PLAUR expression with metastasis of colon cancer patients after radical colectomy (n = 185); Table S9. Correlation between FOXM1 and PLAUR protein expressions in primary colon cancer (n = 203)
Supplementary Table 3 from Predicting Drug Responsiveness in Human Cancers Using Genetically Engineered Mice
Authors: Usary Jerry , Zhao Wei , Darr David , Roberts Patrick J. , Liu Mei , Balletta Lorraine , Karginova Olga , Jordan Jamie , Combest Austin , Bridges Arlene , Prat Aleix , Cheang Maggie C. U. , Herschkowitz Jason I. , Rosen Jeffrey M. , Zamboni William , Sharpless Norman E. , Perou Charles M.
Published: April 2023

XLSX file - 32K, Modules/expression signatures analysis of carboplatin/paclitaxel treated C3(1)-T-antigen mouse tumors.
Supplementary Figure Legend from Predicting Drug Responsiveness in Human Cancers Using Genetically Engineered Mice
Authors: Usary Jerry , Zhao Wei , Darr David , Roberts Patrick J. , Liu Mei , Balletta Lorraine , Karginova Olga , Jordan Jamie , Combest Austin , Bridges Arlene , Prat Aleix , Cheang Maggie C. U. , Herschkowitz Jason I. , Rosen Jeffrey M. , Zamboni William , Sharpless Norman E. , Perou Charles M.
Published: April 2023

PDF file - 68K
Supplementary Figure Legend 1 from Single-Cell Pharmacodynamic Monitoring of S6 Ribosomal Protein Phosphorylation in AML Blasts during a Clinical Trial Combining the mTOR Inhibitor Sirolimus and Intensive Chemotherapy
Authors: Perl Alexander E. , Kasner Margaret T. , Shank Doris , Luger Selina M. , Carroll Martin
Published: April 2023

PDF file - 58K
CCR Translation for This Article from Single-Cell Pharmacodynamic Monitoring of S6 Ribosomal Protein Phosphorylation in AML Blasts during a Clinical Trial Combining the mTOR Inhibitor Sirolimus and Intensive Chemotherapy
Authors: Perl Alexander E. , Kasner Margaret T. , Shank Doris , Luger Selina M. , Carroll Martin
Published: April 2023

CCR Translation for This Article from Single-Cell Pharmacodynamic Monitoring of S6 Ribosomal Protein Phosphorylation in AML Blasts during a Clinical Trial Combining the mTOR Inhibitor Sirolimus and Intensive Chemotherapy
Supplementary Figure 1 from Predicting Drug Responsiveness in Human Cancers Using Genetically Engineered Mice
Authors: Usary Jerry , Zhao Wei , Darr David , Roberts Patrick J. , Liu Mei , Balletta Lorraine , Karginova Olga , Jordan Jamie , Combest Austin , Bridges Arlene , Prat Aleix , Cheang Maggie C. U. , Herschkowitz Jason I. , Rosen Jeffrey M. , Zamboni William , Sharpless Norman E. , Perou Charles M.
Published: April 2023

PDF file - 1229K, Paclitaxel drug concentrations were measured by mass spectroscopy and samplings of MMTV-Neu tumors and plasma. The results show significant systemic delivery of this drug when administered using intraperitoneal injections, both in the tumor and in the plasma.
Data Supplement from CSPG4-Specific Immunity and Survival Prolongation in Dogs with Oral Malignant Melanoma Immunized with Human CSPG4 DNA
Authors: Riccardo Federica , Iussich Selina , Maniscalco Lorella , Lorda Mayayo Saray , La Rosa Giuseppe , Arigoni Maddalena , De Maria Raffaella , Gattino Francesca , Lanzardo Stefania , Lardone Elena , Martano Marina , Morello Emanuela , Prestigio Simone , Fiore Alessandra , Quaglino Elena , Zabarino Sara , Ferrone Soldano , Buracco Paolo , Cavallo Federica
Published: April 2023

Supplementary Materials and Methods and Figure Legends