bluuebunny/crossref_metadata_2025 huggingface dataset:
HIMS-Net: Horizontal-vertical interaction and multiple side-outputs network for cyst segmentation in jaw images
Authors: Jiang Xiaoliang , Zheng Huixia , Yuan Zhenfei , Lan Kun , Wu Yaoyang
Published: February 2024

Jaw cysts are mainly caused by abnormal tooth development, chronic oral inflammation, or jaw damage, which may lead to facial swelling, deformity, tooth loss, and other symptoms. Due to the diversity and complexity of cyst images, deep-learning algorithms still face many difficulties and challenges. In response to these problems, we present a horizontal-vertical interaction and multiple side-outputs network for cyst segmentation in jaw images. First, the horizontal-vertical interaction mechanism facilitates complex communication paths in the vertical and horizontal dimensions, and it has the ability to capture a wide range of context dependencies. Second, the feature-fused unit is introduced to adjust the network's receptive field, which enhances the ability of acquiring multi-scale context information. Third, the multiple side-outputs strategy intelligently combines feature maps to generate more accurate and detailed change maps. Finally, experiments were carried out on the self-established jaw cyst dataset and compared with different specialist physicians to evaluate its clinical usability. The research results indicate that the Matthews correlation coefficient (Mcc), Dice, and Jaccard of HIMS-Net were 93.61, 93.66 and 88.10% respectively, which may contribute to rapid and accurate diagnosis in clinical practice.
A stochastic Gilpin-Ayala mutualism model driven by mean-reverting OU process with Lévy jumps
Authors: Gao Meng , Ai Xiaohui
Published: February 2024

By using the Ornstein-Uhlenbeck (OU) process to simulate random disturbances in the environment, and considering the influence of jump noise, a stochastic Gilpin-Ayala mutualism model driven by mean-reverting OU process with Lévy jumps was established, and the asymptotic behaviors of the stochastic Gilpin-Ayala mutualism model were studied. First, the existence of the global solution of the stochastic Gilpin-Ayala mutualism model is proved by the appropriate Lyapunov function. Second, the moment boundedness of the solution of the stochastic Gilpin-Ayala mutualism model is discussed. Third, the existence of the stationary distribution of the solution of the stochastic Gilpin-Ayala mutualism model is obtained. Finally, the extinction of the stochastic Gilpin-Ayala mutualism model is proved. The theoretical results were verified by numerical simulations.
Predicting nonradiative decay barrier of BODIPY dye in polar environment by applying ONIOM multiscale method
Authors: Narkevičius Domantas , Toliautas Stepas
Published: February 2024

Fluorescent molecular sensors are widely used in biological research. They allow straightforward viscosity, temperature or polarity measurements at the microscopic level, including live cells. Maps of desired physical properties can be obtained by applying fluorescence lifetime imaging microscopy (FLIM) to cells.

One of the most important properties of a cell is viscosity, as it affects other parameters, such as the rate of biochemical reactions and particle diffusion. Boron-dipyrromethene (BODIPY) compounds are widely used for viscosity measurements, but current variants have the undesirable sensitivity to polarity, and more suitable alternatives are being sought using theoretical computations. The polarizable continuum model (PCM) used in previous studies did not adequately take into account the influence of the polar environment when calculating the BODIPY activation energy associated with polarity sensitivity.

After applying the multilayer ONIOM method in polar and non-polar environments, the calculated maximum wavelengths of the fluorescence spectra of the 8PhBODIPY compound were closer to the experimental results compared to PCM. The activation energy was also calculated, its value in polar and non-polar environments qualitatively corresponded to the experimental results, and the quantitative agreement was reached using the empirical correction.
Optical characteristics of structures with silicon nanowires and metal nanoparticles
Authors: Havryliuk Oleksandr O. , Tkachuk Olha , Terebinska Mariia , Semchuk Oleksandr , Biliuk Anatolii
Published: February 2024

To calculate the optical parameters, the finite difference method in the time domain (FDTD) was used, which can be applied to solve Maxwell’s equations. A large number of combinations of a planar structure with metal nanoparticles and a structure with nanowires and metal nanoparticles (NPs) were calculated. The height of nanowires h varied from 50 to 3000 nm, the period of the structure P was 100–600 nm, and the diameter of metal nanoparticles d was 50–400 nm. The reduction of light reflection was determined by the anti-reflection effect of the Si-NWs array itself and the direct scattering effect of metal nanoparticles. It was shown that all structures gave significantly lower reflection coefficients compared to that of a solid silicon plate.
Continuous Glucose Monitoring with Real-Time Readings
Authors: Mohan Viswanathan , Unnikrishnan Ranjit , Mithal Ambrish
Published: February 2024

With 74.2 million people affected, diabetes represents a major burden on India's health-care system and economy. Effective diabetes management is based on diet, lifestyle, pharmacotherapy, and glucose monitoring that are to be individualized for every patient. However, glucose monitoring rates in India are abysmal. The available monitoring techniques have limitations with respect to mostly being single point-in-time readings that may not be entirely reflective of the state of diabetes control. With advancements in technology, the new monitoring tool – continuous glucose monitoring (CGM) – provides visibility into the glycemic profile 24 × 7 with user-friendly reports that provide information much beyond the glycated hemoglobin (HbA1c) and self-monitoring of blood glucose. This innovative tool also detects the time spent in range by the individual with diabetes. This is the new metric endorsed by all reputed medical organizations for diabetes management with multiple benefits ranging from helping slow down the progression to diabetes-related complications to enabling improvement in overall glycemic control. CGM can be classified into personal and professional types based on its usage. Certain types of CGM can also provide real-time (RT) readings either automatically or on-demand. This review article explores the CGM technologies with RT readings in the context of diabetes care in India. These new technologies have the potential to change the way diabetes is managed today including making smart decisions such as the right choice of diet, apt lifestyle modification, and adequate titration of pharmacotherapy (including insulin) while monitoring glucose levels continuously anytime anywhere without a prick.
Positioning “Time-in-Range” in the Treatment of Diabetes in India
Authors: Mohan Viswanathan , Unnikrishnan Ambika G. , Kesavadev Jothydev , Saboo Banshi
Published: February 2024

Recent increases in the usage of continuous glucose monitoring technology have provided people living with diabetes and health-care professionals with access to a variety of novel glucose control indicators. Some of these indicators are valuable for research, while others are useful clinically. Time-in-range (TIR) is a metric that denotes the proportion of time per day that a person's glucose level is within a specified goal range. There is evidence relating TIR to risk of complications and it is becoming an excepted endpoint in clinical trials. There is an inverse relationship between TIR and glycated hemoglobin. In addition, the duration and severity of time below range and time above range are also discussed. This paper summarizes recent guidelines regarding the “TIR” goals for different individuals with different types of diabetes. As is always the case, glycemic objectives should be tailored to the individual. Finally, this article discusses the tool of TIR's positioning in India and the specific populations/patient profiles that will benefit from the intervention.
Glucagon-Like Peptide-1 Receptor Agonists and Thyroid Disorders
Authors: Kesavadev Jothydev , Kovil Rajiv , Basu Debasis , Chaudhuri Soumyabrata Roy , Bhartia Mithun
Published: February 2024

GLP-1 hormone secreted by L cells of intestine increases the glucose mediated insulin release, delay the gastric emptying and increases satiety by central mechanisms. Thus, a potential candidate for treatment of type 2 diabetes mellitus. Various GLP-1receptor analogues with longer half-life were introduced for the benefit of type 2 diabetes management. But animal studies of liraglutide showed increased incidence of thyroid cancers especially C cell hyperplasia in mice. This led to the safety concern of GLP-1RAs in terms of thyroid cancers. But further investigation showed that risk of thyroid cancers in humans is not significant as the receptor mapping in in vitro studies showed that in thyroid glands of humans and primates GLP-1 receptors were not expressed. Considering the safety, the drug was labelled as a contraindication for patients with MEN 2 syndrome or family history of Medullary thyroid cancer. Data from phase 3 trials of all the GLP-1RAs did not show any significant increase in thyroid cancer or any cancer with GLP-1 usage. Meta-analysis of the trials also showed no significant increase in thyroid or any other cancer in comparison to comparators. But two observational studies showed the increase in incidence of thyroid cancers among patients on GLP-RAs, but the studies showed limitations like study design limitation, unaccounted biases, over reporting etc. Surveillance data and review of all available data shows that there is no significant increase in risk of any thyroid disorder and treatment decision to be on risk benefit basis.
Noninvasive Drug Delivery System Progress in Protein and Peptide Delivery
Authors: Jayakrishnan B.
Published: February 2024

Protein and peptide drugs have tremendous therapeutic potential, and their usage in the treatment of various severe diseases has revolutionized the fields of pharmaceuticals and biotechnology. For successful therapeutic effects, several efforts have been made to deliver protein/peptide drugs through various routes of administration. Parenteral and nonparenteral drug deliveries are regarded as significant routes of drug absorption. However, there is a need to improve nonparenteral drug delivery systems (DDSs) through subsequent routes, including buccal, pulmonary, oral, ocular, transdermal, and nasal routes to increase drug absorption effectively. The study evaluated various DDS routes proposed for the distribution of proteins and peptides in terms of both parenteral and nonparenteral delivery systems. For this purpose, numerous research articles were searched from the year 2000 to 2021 using search engines such as PubMed, Google Scholar, Medline, ISI Web of Knowledge, and Bioline International while applying different keywords such as “protein and peptide drugs,” “drug delivery systems,” “parenteral and nonparenteral routes of drug delivery,” and “physicochemical barriers.” The invasive/parenteral routes have several limitations associated with drug delivery, such as poor patient compliance and the pain and discomfort associated with these routes inconvenience in treating the pediatric population. The oral route is one of the most convenient routes of noninvasive or nonparenteral drug administration; here, no pain and discomfort arise, thus helping in maintaining higher patient compliance or acceptance. The other routes of administration of proteins and peptides through buccal, intranasal, pulmonary, transdermal, rectal, and ocular routes have also been showing successful results. The success of the therapeutics is strongly influenced by the differential delivery of the targeted antigen, the choice of targeting protein or peptide, and the drug-release characteristics of the linker used. Furthermore, there should be an improvement in nonparenteral DDSs so that the drugs might be administered appropriately.
Managing Coronavirus Disease – Success Stories from Kerala
Authors: Kesavadev Jothydev , Raj Sumesh , Shiji P. V. , Kumar B. Padma , Raveendran Arkiath Veettil , Moses Bobby , Pillai Anand Marthanda , Prasobh Sunil , Ashik Asha , Krishnan Gopika , Basanth Anjana
Published: February 2024

The coronavirus disease 2019 (COVID-19) pandemic has wreaked havoc on our lifestyle and habits. India, being a highly populated nation, has put up several efforts in the battle against COVID, through the state and national governing bodies. A small, southern state of India, Kerala, gained a worldwide appreciation for its stupendous toil against the COVID attacks. Kerala also achieved impressive milestones in the areas of education and maternal health. Spontaneous measures taken for quarantine, isolation, treatment drugs, and therapeutic facilities have definitely helped during the course. Even so, with the onset of different variants of COVID, Kerala could not contain the rise in cases during the third phase. The stress and social isolation have created a negative impact on livelihood. This paper discusses the impact of COVID on different aspects including metabolic and systemic diseases, treatment, medical education, government measures, and case surge.
One Hundred and One Years of Insulin Delivery with Transition from Syringes to User-Friendly Technologies
Authors: Kesavadev Jothydev , Saboo Banshi , Benny Nelena , Basanth Anjana , Krishnan Gopika , Shankar Arun , Jothydev Sunitha
Published: February 2024

In people with diabetes, the most efficient therapeutic option available to reduce hyperglycemia continues to be insulin, even though they experience numerous challenges with the use of insulin. Beginning with the syringe for injecting insulin, progressing to insulin pens, insulin pumps, and sensor-augmented pumps, the growth of diabetes technologies accelerated with the introduction of hybrid closed-loop systems, integration with consumer electronics, and cloud-based data systems. There has been a high-speed evolution in diabetes technologies to improve the quality of life and to extend the endurance of subjects with diabetes. Although there were commendable developments in the currently available devices, many of those were prohibitively expensive. The ultimate dream is to develop an artificial pancreas capable of 100% time in range and 0% time below range and affordable to everyone. Even though the mission demands enormous commitment and time, it has the potential to transform diabetes therapy.
Constrictive Pericarditis: An Update on Noninvasive Multimodal Diagnosis
Authors: Restelli Davide , Carerj Maria Ludovica , Bella Gianluca Di , Zito Concetta , Poleggi Cristina , D’Angelo Tommaso , Donato Rocco , Ascenti Giorgio , Blandino Alfredo , Micari Antonio , Mazziotti Silvio , Minutoli Fabio , Baldari Sergio , Carerj Scipione
Published: February 2024

Constrictive pericarditis (CP) is a rare condition that can affect the pericardium after every pericardial disease process and has been described even after SARS-CoV-2 infection or vaccine. In CP, the affected pericardium, usually the inner layer, is noncompliant, constraining the heart to a fixed maximum volume and impairing the diastolic function. This leads to several clinical features, that, however, can be pleomorphic. In its difficult diagnostic workup, noninvasive multimodal imaging plays a central role, providing important morphological and functional data, like the enhanced ventricular interdependence and the dissociation between intrathoracic and intracardiac pressures. An early and proper diagnosis is crucial to set an appropriate therapy, changing the prognosis of patients affected by CP. In this review, we cover in detail the main elements of each imaging technique, after a reminder of pathophysiology useful for understanding the diagnostic findings.
A Case of Late Presentation of Supracardiac Total Anomalous Pulmonary Venous Connection in an Adult
Authors: Prakash Avinash , Jhalani Ishan , Darbari Anshuman , Kumar Ajay
Published: February 2024

Total anomalous pulmonary venous connection (TAPVC) is a rare cyanotic congenital heart disease and their survival into adulthood is even rarer. Here, we present the case of a 26-year-old female who was incidentally diagnosed with a case of supracardiac TAPVC during her pregnancy. All four pulmonary veins were joining to form a common venous confluence which drained into a left-sided vertical vein which drained into the innominate vein.
Can Global Longitudinal Strain Assess Asymptomatic Subtle Left Ventricular Dysfunction in Recovered COVID-19 Patients?
Authors: Mansour Hazem , Abdelhady Aly Osama , Reheim Walaa Adel Abdel , William Viola
Published: February 2024

Background:

Coronavirus disease 2019 (COVID-19) might be associated with cardiac injury as a part of multisystem affection in response to cytokine storms. However, left ventricular (LV) function appears preserved in most of the cases, whereas subtle LV dysfunction might happen in others. Hence, we tried to detect subtle LV dysfunction in patients with COVID-19 using global longitudinal strain (GLS).

Patients and Methods:

We performed a single-center observational study on 90 stable patients who were recently recovered from mild to moderate COVID-19 infections. A transthoracic echocardiographic examination was done for all patients, and GLS assessment was used as an indicator of LV function.

Results:

The population age ranged from 27 to 66 years, and the majority of patients were males (54, 73.3%). Besides, 46.7% of the included patients were smokers, 33.3% had hypertension, and 23.3% were diabetics. All the patients had normal LV internal dimensions and ejection fractions. However, 33.3% of them had subclinical LV dysfunction as expressed by reduced GLS. There was no statistically significant correlation between GLS and age, gender, or other risk factors, whereas troponin and C-reactive protein significantly correlated with GLS.

Conclusions:

Recovered patients from recent mild to moderate COVID-19 infections might show subtle LV dysfunction as manifested by reduced GLS.
Percepții ale studenților din anul I din domeniul silvicultură privind gestionarea pădurilor
Authors: Barbu Cătălina , Scriban Ramona-Elena , Horodnic Sergiu-Andrei
Published: February 2024

Asigurarea unei gestionări durabile a pădurilor este principiul fundamental al managementului forestier și e adresată la nivel legislativ în România, silvicultorii fiind provocați să răspundă și să se adapteze cerințelor și condițiilor unei societăți moderne, societate aflată într-o continuă evoluție. Astfel, competențele oferite de învățământul superior silvic trebuie în permanentă adaptate pentru a ține pasul cu evoluția societății. Prezentul studiu are drept scop analiza percepțiilor studenților anului I din cadrul Facultății de Silvicultură din Suceava asupra gestionării pădurilor din România. Pentru realizarea studiului s-a folosit metoda anchetei pe bază de chestionar. Studiul a fost realizat pe un eșantion de 252 de studenți (197 băieți și  55 fete) în perioada 2015-2020. 75% dintre respondenți consideră că pădurile României nu sunt gestionate corespunzător, că aceste păduri sunt tăiate abuziv și ilegal (84%) și mult mai mult decât în ​​alte țări europene (75%). În ceea ce privește tăierile de pădure în următorii 10 ani, 56% sunt de părere că acestea ar trebui oprite total în timp ce 23% consideră că mai degrabă nu. Părerile studenților anului I asupra imaginii gestionării pădurilor private sunt împărțite în mod egal. Astfel 34% consideră că imaginea s-a deteriorat, 33% consideră că imaginea s-a îmbunătățit și 33% că a rămas la fel. În cazul gestionării pădurilor de stat procentul celor care cred că situația s-a deteriorat este identic cu al celor care cred că situația a rămas la fel (38%). Doar 24% consideră că situația s-a îmbunătățit. Studiul oferă  informații esențiale atât pentru direcțiile de comunicare cu publicul larg și de îmbunătățire a educației forestiere la nivel pre-universitar pentru de-mitizarea unor teme percepute distorsionat față de realitățile datelor statistice existente, dar și asupra direcțiilor de îmbunătățire a curriculei universitare necesar a fi adaptate pentru a adresa cu fundamente științifice preocupările studenților privind problematicile de gestionare a pădurilor naționale.
Rolul serviciilor ecosistemice culturale în managementul sustenabil – studiu de caz în pădurile administrate de ocoale silvice de regim din România
Authors: Scriban Ramona-Elena , Drăgoi Marian , Bădăluță Carmen , Bouriaud Laura
Published: February 2024

Serviciile ecosistemice culturale oferă o serie de beneficii pentru bunăstarea umană, dar dintr-o perspectivă identitară. Aceste beneficii includ experiențe estetice, cunoștințe și abilități, spiritualitate, implicarea în conservarea naturii, ceea ce înseamnă că, indirect, serviciile culturale asigură conservarea tuturor formelor de viață. Conceptul de servicii culturale ale ecosistemelor a devenit din ce în ce mai important în ultimii ani, deoarece ajută la înțelegerea valorii socio-culturale a pădurilor și la echilibrarea intereselor părților interesate în gestionarea pădurilor. În România, serviciile ecosistemice sunt recunoscute prin funcțiile de protecție și de producție atribuite pădurilor. Din fericire, sistemul forestier românesc integrează numeroase servicii ecosistemice în procesul de elaborare a managementului forestier, prima corelație între categoriile funcționale specifice fiecărui tip de arboret și măsurile silvice propuse. Mai mult decât atât, instrumentele de politică Forestiera mixtă pentru serviciile ecosistemice forestiere fac referire la documentele necesare privind armonizarea planificării silvice cu planul de management al ariilor naturale protejate și cu cele complementare oferite de sistemul de certificare FSC. Serviciile ecosistemice culturale se confruntă cu mai multe provocări, una dintre acestea fiind lipsa unor concepte coerente care împiedică evaluarea și integrarea serviciilor ecosistemice forestiere în proiectarea arhitecturii peisajului. Rezultatele analizei arată că pădurile cu rol cultural identificate prin procesul de certificare se referă, în general, la pădurile din apropierea clădirilor culturale și/sau de patrimoniu (cum ar fi bisericile și mănăstirile) sau la pădurile care oferă valori estetice și/sau recreative importante. În mod evident, certificarea managementului forestier contribuie, printr-o abordare metodologică simplă, la identificarea pădurilor cu rol cultural, în special în situațiile în care planurile de management forestier nu le acordă prioritate din cauza limitărilor impuse de criteriile de zonare funcțională. Mai mult de 40% din pădurile culturale analizate au un rol recreativ și ecoturistic, urmate de cele cu valoare spirituală sau religioasă, cu 18% din suprafața totală a pădurilor culturale analizate. Deși prin acest studiu au fost identificate șapte tipuri de servicii ecosistemice culturale, componenta de diversitate culturală este imposibil de diferențiat la nivel național, deoarece diversitatea culturală implică existența populațiilor indigene. În schimb, studiul poate fi extins la o scară mai mare pentru a identifica mai multe păduri cu valoare inspirațională sau estetică, ambele valorificate la nivel de peisaj.
Conferința internațională "Integrated Management of Environmental Resources" – a VI-a ediție
Authors: Nichiforel Liviu , Duduman Gabriel
Published: February 2024

Desfășurată în 23-24 Noiembrie 2023, cea de a șasea conferință "Integrated Management of Environmental Resources" organizată de Facultate de Silvicultură din Suceava a adus în atenția participanților 46 de prezentări şi 17 postere, acoperind subiecte precum conservarea biodiversităţii, utilizarea durabilă a pădurilor, evaluarea şi modelarea ecosistemelor forestiere, gestionarea resurselor de apă şi adaptarea la schimbările climatice. De asemenea, în cadrul conferinței s-a organizat o vizită practică în Codrul Secular Slătioara, unde principalele instituţii de învăţământ superior silvic şi de cercetare din ţară au discutat problematica transferului tehnologic şi a unei abordări holistice, orientate spre practică, în gestionarea resurselor forestiere
Un colocviu de succes în lumea Regelui-Soare...
Authors: Nicolescu Valeriu-Norocel
Published: February 2024

Cronica prezintă cele mai importante rezultate ale colocviului intitulat „Le bois, source de ressource durable - un acteur de la transition” și realizat în cadrul schimburilor existente din anul 2019 între SCNF (Société nationale des chemins de fer français) și Societatea franco-japoneză de tehnici industriale.

Colocviul a inclus conferința propriu-zisă, găzduită la Versailles (23-25 octombrie), precum și două zile pe teren, în regiunea lorenă (nord-estul Franței) (26-27 octombrie).

            Gazda colocviului a fost École nationale supérieure de paysage (ENSP), instituție de învățământ superior creată în anul 1976 și care funcționează în spațiile fostei École nationale supérieure d’horticulture, înființată la Versailles în anul 1874.

Manifestarea de la Versailles a urmărit să abordeze problema asigurării și utilizării raționale și durabile a resurselor de lemn, ținând cont și de aspecte legate de biodiversitate și de funcțiile sociale ale pădurilor. În consecință, colocviul și-a propus un schimb de idei intre „actorii” care participă la producerea și transformarea „acestui material cu calități excepționale” și utilizatorii lui finali.

            Cele trei zile de conferință s-au desfășurat în trei direcții: (1) Abordarea istorică și socială a pădurilor, (2) Reconcilierea resurselor de lemn cu biodiversitatea și (3) Anticipare, cu numeroase prezentări în legătură cu temele amintite.

            Colocviul a continuat cu o deplasare pe teren în zona lorenă a Franței, unde gazda primei zile a vizitei pe teren a fost stațiunea de la Champenoux a Centrului de cercetări Grand Est-Nancy din cadrul INRAe, organismul de cercetare agricolă, alimentară și de mediu, inclusiv forestier, al Franței. Aici ni s-a prezentat activitatea stațiunii, care găzduiește trei unități de cercetare Forestiera, laboratoarele din incinta acesteia, precum și Arboretumul Amance, aflat în proximitate.

În ultima zi, participanții s-au deplasat în Forêt de Haye, un masiv forestier de cca 11.000 ha, din care 6500 ha păduri de stat, situat în apropiere de Nancy. Dintre aspectele cele mai sugestive ale vizitei pe teren se pot aminti (i) posibilitatea exploatării arborilor din rărituri  cu ajutorul harvesterelor (combine de exploatări), după însemnarea cu vopsea a exemplarelor de extras și deschiderea culoarelor de acces, (ii) problemele deosebite cu fenomenul de uscare a fagului, mai ales pe soluri foarte superficiale (doar 20-30 cm de orizont mineral), pe fondul absenței de lungă durată a precipitațiilor în decursul sezonului de vegetație, (iii) interesul special acordat speciilor rare și cu lemn prețios gen Sorbus torminalis sau Sorbus domestica în timpul aplicării operațiunilor culturale, specii a căror creștere în grosime este favorizată prin intervenții de sus, urmărind situarea lor în condiții de creștere liberă (fără competiție) la nivelul coroanei.
Using a Blended Learning Approach to Encourage Course Interaction in a First-Year Business Communication Module
Authors: Mdletye Zizipho , Usadolo Sam Erevbenagie
Published: February 2024

The aim of the study is to examine the effectiveness of blended learning in encouraging course interaction amongst first-year students studying a business communication module. The COVID-19 pandemic resulted in the increased use of blended learning as a teaching approach to encourage learning regardless of the location. Existing research on blended learning suggests its value in promoting increased student engagement, ultimately contributing to positive educational outcomes. Data was collected through a cross-sectional survey whereby a questionnaire was distributed to the respondents using Google Forms. Data was analysed on the same platform. Cross-tabulation was used to understand the relationships between factors in participants’ responses to the questions. Results indicate that blended learning successfully drives course interaction because the combination of class-based and online engagement positively impacts how likely students are to engage in course content. This paper makes a valuable contribution in the form of underscoring a pressing need for research that is aimed at understanding how blended learning shapes the experiences students have with their modules, as well as how these factors may shape current practices in blended learning. Most students indicated that they would recommend blended learning as it increased participation and engagement with their course content.
Pelatihan Pengolahan Makanan Lokal untuk Peningkatan Gizi dan Pendapatan Keluarga di Desa Pantai Labu
Authors: Mahdiah Mahdiah , Nurhayati Ida , Nasution Zuraidah
Published: February 2024

Pantai Labu Pekan Village, Pantai Labu District, Deli Serdang Regency, is one of the villages whose area is located on the coast. According to the research conducted, there are still toddlers who experience stunting and malnutrition, the low coverage of poverty, and the low knowledge of pregnant women in toddlers causes the growth and development of toddlers to be disrupted and this can affect their health status broadly. The purpose of this research is to apply science and technology to the community to increase knowledge and skills in the health sector, form/develop community groups in the health sector, apply research results to improve public health for the welfare of public health. This research is observational research with a descriptive research design. The research was conducted in June 2023 in Pantai Labu Pekan Village, Pantai Labu District. In this Community Service activity, the methods carried out were training in local pagan-based snack food processing for pregnant women and WUS and conducting demonstrations on making sukahitu cookies, moringa leaves, fish nuggets, fish sandwiches, rebon shrimp crackers and satay donuts. This program to increase the knowledge of pregnant women and wus starts from 4 stages, namely licensing, preparation, implementation and evaluation. The results of community service activities are that there is an increase in the knowledge of pregnant women and WUS about snack foods which can help in efforts to deal with stunting and there is an increase in the knowledge of pregnant women and WUS about snack foods. From snack foods that are highly nutritious to prevent stunting and snacks containing moringa leaves as a way to overcome anemia and breast milk production.
Conhecimento dos acadêmicos a cerca do diagnóstico e tratamento precoce da HMI na infância
Authors: Marinho Rebeca Bastos Vasconcelos , Vasconcelos Raquel Bastos , Aguiar Lila Parente
Published: February 2024

A Hipomineralização Molar Incisivo (HMI) é uma displasia que ocorre no esmalte dentário que afeta principalmente os primeiros molares permanentes e podem ter uma associação aos incisivos permanentes, apresentando-se de forma demarcada, opaca e possui colorações brancas, amarronzadas ou amareladas. O objetivo deste trabalho foi analisar o conhecimento dos acadêmicos do curso de Odontologia, acerca do diagnóstico e tratamento da HMI na infância. Trata-se de uma pesquisa do tipo quantitativa, descritiva e transversal realizada no Centro Universitário Christus com discentes do curso de odontologia, que cursavam do oitavo ao décimo semestre durante o período de levantamento da pesquisa. A coleta de dados foi através de um questionário estruturado e enviado através do Google Forms. Os dados quantitativos foram tabulados, e foram calculadas as frequências absolutas e percentual de acertos de cada questão associadas ao semestre. Dos 83 discentes que responderam a pesquisa, o acerto predominante em relação ao diagnóstico foi o da hipomineralização molar incisivo moderada onde 98,8% acertaram o diagnóstico. Enquanto o acerto predominante em relação ao tratamento foi de 92,8%, em que optaram por restauração direta com resina composta ou CIV. A HMI permanece ainda relativamente subdiagnosticada e de etiologia não totalmente definida, tornando o diagnóstico e tratamento na infância mais dificultado. Percebeu-se que os discentes ainda possuem dificuldade no diagnóstico diferencial e na escolha da melhor opção terapêutica, assim, novas pesquisas são necessárias para estimular e difundir o conhecimento dentre os cirurgiões-dentistas desde sua formação acadêmica, com o objetivo de melhorar o prognóstico desses pacientes infantis.
Use of potassium iodide in the treatment of sporotrichosis in dog after failure treatment with ketoconazole and itraconazole – a case report
Authors: Hathaway Grassani Martha , Crissiuma de Azevedo Juppa Ana Lucia
Published: February 2024

Sporotrichosis is a disease that affects humans and animals in a subacute or chronic form. It is considered the most common subcutaneous mycosis in Latin America, having reached epidemic proportions in the state of Rio de Janeiro. The infected cat is the main transmitter of the disease. Although it occurs less frequently in dogs, studies report an increase in the number of cases since 1998. The treatment of fungal infections in animals is a challenge for veterinarians, since the majority of systemic antifungal agents have significant adverse effects. This study reports a case of canine sporotrichosis that was refractory to the use of ketoconazole and itraconazole that was treated with potassium iodide. We conclude that potassium iodide in capsules is an alternative for the treatment of canine sporotrichosis in cases that are refractory to conventional treatment with ketoconazole and itraconazole.
An update on inflammatory bowel disease
Authors: Ricart María Cecilia , Feijoó Silvia Martha , Gómez Nélida Virginia
Published: February 2024

Inflammatory bowel disease is a chronic disorder in dogs and cats characterized by gastrointestinal signs, inflammatory mucosal changes detected on histopathology and inadequate response to anthelmintics or dietary therapies. Etiopathogenesis is unknown, but it is believed that the condition could be caused by abnormal function of the gut-associated lymphoid tissue, or by an overtly aggressive immunological response against inflammation-causing luminal antigens, which would in turn affect intestinal motility. Diagnosis is achieved through fecal parasitological examination, blood analysis, abdominal ultrasonography, endoscopy or laparotomy for retrieval of samples from the complete intestinal wall, and histopathology. The aim of this article is to provide an update about this complicated disease.
A descriptive study on anxiety separation syndrome (ASS) in dogs
Authors: Spiller Paulo Roberto , Alonso Novais Adriana , Mota dos Santos Moretto Viviane
Published: February 2024

The aim of this study was to verify the occurrence of anxiety separation syndrome (ASS) in dogs from Sinop/MT, Brazil. For this purpose, a questionnaire was developed and applied to owners of one hundred male and female dogs of both pure breed and mixed breeds from local veterinary clinics or from the Veterinary Hospital of UFMT, Campus Sinop. Results showed 28% prevalence of ASS among the studied population. Most frequent symptoms were excessive vocalization (60.7%), inappropriate urination (50%), destructive behavior (35.7%) and inappropriate defecation (17.8%). All positive dogs showed owner hyperattachment, and 32.1% (9 animals) had compulsive disorder. Results indicated a significant prevalence of ASS in dogs from Sinop; further research should be developed to measure its impact on animals and human society.
Erythrocyte oxidative changes in dogs – retrospective study of 62 cases (2009-2011)
Authors: Spina Artacho Nathália , Bacic Angela , Aravena Claudia , Balda Ana Cláudia
Published: February 2024

Oxidative erythrocyte alterations may result from the ingestion of toxins, oxidants in the diet, metabolic and neoplastic diseases, as well as drugs. The aim of this study is to report the prevalence of erythrocyte oxidative changes in a veterinary hospital and its possible association with drug use and associated diseases. After analysis of 3,300 reports of blood counts, we identified 62 (1.8%) cases of eccentrocytes and/or Heinz bodies. In most of these, a combination of drugs was used, including dipyrone, in animals with chronic diseases such as infections, neoplasia and degenerative diseases. We suggest careful hematologic follow-up of animals with such diseases, especially those with prior anemia and hyporexia that may need longterm treatment with a combination of drugs, and which are also at risk of being given oxidant substances in their diet to stimulate food ingestion.
Grape intoxication in a dog – case report
Authors: Pereira Luiz Carlos , Sarkis Vieira Ana Luiza , Brillante Cardinot Cinthya , de Carvalho Guedes Roberto Maurício
Published: February 2024

Animal poisoning by consumption of human food occurs often and is generally caused by owners themselves. The grape (Vitis vinifera) can cause poisoning in dogs both in natura and in its dehydrated form (raisin), but its potential toxicity is still little known by veterinarians. This paper reports the case of a fivemonth-old Spitz that developed clinical signs of acute renal failure after eating a bunch of grapes. The clinical course was characterized by vomiting, diarrhea, anuria and increased levels of creatinine and urea. The animal died 18 hours after admission. Anatomical and histopathological exams showed acute tubular necrosis with foci of mineralization. Together, the clinical, laboratory and pathological findings are consistent with a case of renal failure caused by grape ingestion.
Diagnostic imaging of thyroid diseases in dogs – review
Authors: Müller Thiago Rinaldi , Pasini Souza Livia , Pulz Doiche Danuta , Mamprim Maria Jaqueline , Bertelis Merlini Natalie
Published: February 2024

The diagnosis of various diseases has become more accessible and accurate with the rapid development of imaging modalities aiming to assist in medical diagnosis, and thereby in veterinary medicine. Different diagnostic imaging modalities such as ultrasonography, computed tomography, magnetic resonance imaging and scintigraphy can be performed to obtain information about thyroid diseases, each one with advantages and disadvantages, depending on the thyroid disease in question. Diagnostic imaging is a tool that not only assists in the diagnosis, but also helps treatment and assessment of prognosis of thyroid diseases. The aim of this article is to discuss the limitations and benefits of each diagnostic imaging modality available in the veterinary medical field, and also to present the newest diagnostic imaging modalities in order to maximize and make more accurate diagnosis of thyroid diseases.
Biogás: análise dos pontos positivos e negativos e sua contribuição para atingir os Objetivos do Desenvolvimento Sustentável (ODS)
Authors: Ferreira Glaucia Lorena , Masetto Antunes Sandra Regina , Ferreira de Souza Eder Carlos
Published: February 2024

O crescimento populacional reflete-se no aumento da demanda energética, no esgotamento de recursos naturais, na geração de resíduos e no aumento da emissão de gases de efeito estufa. Estes fatores causam impactos ambientais e desequilíbrio do meio. Uma forma de minimizar esses impactos é o aproveitamento do biogás. Com o crescimento do número de unidades geradoras em território nacional, o objetivo dessa revisão é avaliar os pontos positivos do biogás, bem como os pontos negativos (presença de H2S no biogás), avaliando as técnicas disponíveis para a dessulfurização do biogás. A versatilidade de aplicação do biogás, aliada a possibilidade de gestão correta de resíduos orgânicos, contribui para a inserção e cumprimento dos Objetivos do Desenvolvimento Sustentável (ODS).
Modelagem, simulação e análise de desempenho de uma planta solar com módulos mono e bifaciais em distintos tipos de solo
Authors: Lamas Dias Douglas , Arns Rampinelli Giuliano
Published: February 2024

O desenvolvimento sustentável é um dos desafios da sociedade contemporânea. Nesse contexto, a inserção de energias renováveis é uma importante estratégia para a transição energética. A energia solar fotovoltaica é uma tecnologia madura, confiável, economicamente competitiva e sustentável. Os módulos fotovoltaicos convertem energia solar em energia elétrica. Ao longo dos anos, o desenvolvimento tecnológico tem sido fundamental para aumentar a eficiência e o desempenho desses módulos. Em particular, os módulos fotovoltaicos bifaciais estão em destaque por serem capazes de aproveitar melhor a radiação solar. Eles aproveitam o albedo do solo, podendo captar energia tanto na parte frontal quanto na parte traseira dos módulos, ao contrário dos módulos monofaciais comumente encontrados no mercado, que aproveitam apenas a energia solar na face frontal. No Centro de Ciências, Tecnologias e Saúde (CTS) da Universidade Federal de Santa Catarina (UFSC), foi instalada uma planta solar composta por dois sistemas fotovoltaicos. Um sistema utiliza módulos monofaciais e apresenta potência nominal de 5,52 kWp, enquanto o outro sistema utiliza módulos bifaciais e apresenta potência nominal de 6,36 kWp. Esses sistemas estão instalados em diferentes tipos de solo: areia clara, brita escura e brita branca, cujos albedos são, respectivamente, 0,4, 0,1 e 0,45. O objetivo do estudo é modelar, simular e analisar o desempenho da planta solar com módulos monofaciais e bifaciais nos diferentes tipos de solo. Os resultados foram comparados com base na irradiação solar global do plano inclinado, na produtividade do sistema, na produtividade do arranjo fotovoltaico e na produtividade de referência. Além disso, foram analisados a razão de desempenho do sistema, o desvio padrão e o ganho bifacial. Os dados utilizados foram provenientes de simulações e obtidos por meio da modelagem no software System Advisor Model (SAM), desenvolvido pelo Laboratório Nacional de Energias Renováveis (NREL). Os resultados mostraram que a irradiação solar global do plano inclinado foi maior para os módulos bifaciais, devido à captação da radiação frontal e traseira. Em relação à produtividade, foram observados ganhos bifaciais, em média mensal anual, de 10,7% para o solo de brita branca, de 9,6% para o solo de areia clara e 2,7% para o solo de brita escura. A razão de desempenho dos dois sistemas da planta solar variou entre 87% e 91%, valores considerados aceitáveis para módulos fotovoltaicos atuais.
Comparison of Log and Empirical High Function Saturation and It’s Effect on Volumetric Calculations
Authors:   Trisakti University,Jalan Letjen S Parman no 1 Kampus AJakarta Indonesia, Benyamin Benyamin , Burhannudinnur M ,   Trisakti University,Jalan Letjen S Parman no 1 Kampus AJakarta Indonesia, Ayu Dyah ,   Trisakti University,Jalan Letjen S Parman no 1 Kampus AJakarta Indonesia, Guntoro Agus ,   Trisakti University,Jalan Letjen S Parman no 1 Kampus AJakarta Indonesia, Djambak Ali ,   Trisakti University,Jalan Letjen S Parman no 1 Kampus AJakarta Indonesia, Hendrasto Fajar ,   Trisakti University,Jalan Letjen S Parman no 1 Kampus AJakarta Indonesia, Rendy Rendy ,   Trisakti University,Jalan Letjen S Parman no 1 Kampus AJakarta Indonesia
Published: February 2024

This paper discusses the comparison of the Saturation Height Function between the saturation calculation method based on log data using various equations such as Archie, Indonesia and Dual Water with the empirical method which is popularly used in the oil and gas industry, namely the Cuddy method. The advantages and disadvantages of each method will be discussed. Each method of calculating saturation with log data is compared with the Cuddy method to get an idea of ​​which geological conditions are most suitable for the Cuddy method. This study was carried out by modeling the well oil saturation height profile from an Oligocene well from the North West Java Basin of Indonesia. This well was chosen because it did not have complete data, only a series of Electrical logs and no conventional core and SCAL data. Apart from comparing each method on the well, this paper also compares volumetric calculations based on the resulting oil saturation height profile model.By comparing the results of each volumetric calculation, we can find out which method gives better results so that without core data we can still make STOIIP predictions quite validly.
Upper Limb Reconstruction with Latissimus Dorsi Flap
Authors:   Centro Médico Nacional Lic. Adolfo López Mateos Toluca Estado de México, Ortega Dr. Héctor Manuel Suarez , Garcia Dr. Williams Antonio Barrios ,   Instituto Superior de Ciências da saude Carlos Chagas, Mercado Dr. Sergio Domínguez ,   Centro Médico Issemym Toluca, González Dr. Román Esteban Hernandez ,   Hospital General de Zona 1 IMSS Tlaxcala, Brito Piñan Dra. Lourdes Montserrath ,   Universidad Autónoma del Estado de Morelos, Castañeda Dra. Michell Flores ,   Centro Médico Nacional Lic. Adolfo López Mateos Toluca Estado de México, Trejo Rubio Dra. Marisela Estefhanía ,   Hospital de Especialidades Centro Médico Nacional la Raza, Robles Dra. Bárbara Alejandra Niño ,   Hospital General "Gral. José María Morelos y Pavón" ISSSTE, Zarate Dr. Ricardo Rene Arrazola ,   Hospital Regional de alta Especialidad Dr. Gustavo A. Rovirosa Pérez
Published: February 2024

The latissimus dorsi flap (LDF) is a surgical technique used by surgeons to rebuild many different types of breast cancer surgical defects, such as modified radical mastectomy, quadrantectomy, and lumpectomy. The LDF can be utilized as an autogenous flap alone, in conjunction with implant-based immediate reconstruction, in conjunction with tissue expanders for a phased reconstruction, or in either case, either immediately or later. During breast reconstruction, the LDF is a dependable soft tissue covering option that offers shape and function with manageable short- and long-term morbidities. When tissue is scarce, the LDF can help by providing tissue volume in autologous reconstruction. It can also serve as a dependable vascular pedicle for implant-based repair in situations when the tissue has been exposed to radiation.
Forearm Position Influences Triceps Brachii Activation During Triceps Push-Down Exercise
Authors: Villalba Marina Mello , Fujita Rafael Akira , Iossi Junior Claudinei , Machado Gomes Matheus
Published: February 2024

Introduction: This study investigated the influence of forearm position (supinated or pronated) on the EMG activity of the triceps brachii lateralis head (TLA), triceps brachii longus head (TLO), flexor carpi radialis (FR), and extensor carpi radialis (ER) muscles during the triceps push-down exercise. Also, we analyzed the effect of different grips (handle vs standard padded pulley strap) to verify EMG activity of these muscles. Methods: Twenty-two adults participated in this study. They performed the single-arm triceps push-down exercise in four conditions: pronated forearm with handle (PRON-H), supinated forearm with handle (SUP-H), pronated forearm with standard padded pulley strap (PRON-S), and supinated forearm with standard padded pulley strap (SUP-S). Surface electrodes were placed over the TLA, TLO, FR, and ER on the dominant side. Results: The TLO showed higher EMG activity for SUP-H compared to all other conditions (p<0.001). Also, the FR EMG activity was higher with PRON-H condition (p<0.001), while the ER EMG activity was higher with SUP-H condition (p<0.001). Regarding the number of repetitions, participants performed fewer repetitions in the SUP-H condition compared to the PRON-H (p<0.001). Conclusion: Our study suggests that the position of the forearm during the triceps push-down exercise has a significant impact on the recruitment of specific muscles and overall exercise performance.