bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of combining valsartan and amlodipine in the treatment of type 2 diabetes mellitus complicated by hypertension
Authors: Chen Hongyan , Niu Wenfang , Liu Chunling , Yin Xiuxiu
Published: January 2024

Purpose: To investigate the efficacy of combining valsartan and amlodipine on patients who were co-morbid with type 2 diabetes mellitus (T2DM) and hypertension.

Methods: The medical records of 110 patients treated in North China Electric Power University Hospital, Beijing, China from July 2018 to October 2022 were retrospectively analyzed. Control group (CG; n = 50) was administered oral amlodipine (5 mg daily for 6 months), while the study group (SG; n = 60) received one tablet of co-formulated valsartan (80 mg)) and amlodipine (5 mg) daily for 6 months. All the patients, in addition to the above drugs, were also placed on insulin and atorvastatin calcium. After a 6-month treatment period, the therapeutic effect and incidence of adverse effects were compared between CG and SG. Blood glucose-related indices (glycosylated hemoglobin (HbA1c), 2 h postprandial blood glucose (2 h PG), and fasting blood glucose (FBG)) and blood pressure indices, viz, (diastolic blood pressure (DBP), systolic blood pressure (SBP)) were compared.

Results: Compared to the pre-treatment values, both groups showed significant decrease in 2 h PG, FBG, HbA1c, SBP and DBP after treatment (p < 0.05), but the 2 h PG, FBG, HbA1c, SBP and DBP in SG were significantly lower in comparison to CG (p < 0.05). The overall response rate (ORR) of CG was significantly lower in comparison to SG (p < 0.05). In SG, there was significant reduction in the incidence of adverse effects compared to CG (p < 0.05).

Conclusion: The combination of valsartan and amlodipine is effective in treating T2DM co-morbid with hypertension, and satisfactorily controls blood glucose level and blood pressure with a relatively high level of safety. Further experiments would be required to ascertain the reliability of these findings.
Effect of Dentong Xiaoyanling and tinidazole gargle on periodontal parameters in chronic periodontitis, gingival sulcus factor and oral health
Authors: Xu Junxian , Lu Lanfang
Published: January 2024

Purpose: To investigate the effect of concentrated tinidazole gargle combined with Dentong Xiaoyanling on chronic periodontitis.

Methods: Ninety-six (96) patients with chronic periodontitis admitted in Chun’an County Traditional Chinese Hospital, Qiandaohu Town, China between January 2021 and December 2022 were randomly divided into two groups: control group (treated with concentrated tinidazole gargle) and study group (treated with concentrated tinidazole gargle + Dentong Xiaoyanling). Periodontal indicators, Gingival sulcus factor (GSF), oral health status, clinical efficacy and adverse reactions were compared between the two groups.

Results: There were no significant changes (p > 0.05) in periodontal indicators, GSF or oral health score between the two groups prior to therapy. However, following treatment with Dentong Xiaoyanling and/or concentrated tinidazole gargle, the periodontal indicators, GSF and oral health score of the two groups reduced significantly (p < 0.05), with more pronounced reductions in the study group. Clinical efficacy in the group treated with a combination of concentrated tinidazole gargle and Dentong Xiaoyanling was 91.67 %, which was significantly higher (p < 0.05) than that of control group (75 %). Furthermore, there was no significant difference in the incidence of adverse reactions between the two groups pre- and post-treatment (p > 0.05).

Conclusion: Treating chronic periodontitis with concentrated tinidazole gargle + Dentong Xiaoyanling alleviates local inflammatory reaction of gums, enhances recovery from symptoms and improves oral health. Future approaches will require a larger sample size from diverse clinical settings to confirm the effectiveness of this approach.
Effect of peri operative whole high quality nursing care on psychological status, vital signs and anesthetic medication of patients undergoing painless gastrointestinal endoscopy : A systematic review and meta analysis
Authors: Huang Qian , Li Yu , Luo Xi , Luo Rong , Zhang Hao
Published: January 2024

Purpose: To investigate the impact of perioperative whole high-quality nursing care on psychological status, vital signs and anesthetic medication of patients undergoing painless gastrointestinal endoscopy, and also to provide a reference for reducing adverse risks and improving safety of painless gastrointestinal endoscopy.

Methods: Databases such as Pubmed, Embase, Web of Science, and Cochrane Library were retrieved. Literature was selected based on established standards, and quality evaluations were performed to extract required data. Finally, 13 pieces of literature were included for meta-analysis of relevant data.

Results: In a meta-analysis of 13 relevant randomized controlled trials (RCTs), patients receiving high-quality perioperative nursing care experienced significant improvements in self-reported anxiety and depression levels, vital signs indicators such as systolic and diastolic blood pressure, mean arterial pressure, and heart rate, as well as decrease in narcotic drug dosage. Diagnosis and treatment time also significantly decreased (p < 0.05). Additionally, the incidence of respiratory depression was reduced (p < 0.00001).

Conclusion: This meta-analysis suggests that perioperative high-quality nursing care alleviates the psychological stress of patients with painless gastrointestinal endoscopy, reduces the amount of anesthesia, and effectively reduces application time of endoscopy
Volumetric modulated arc therapy as an alternative to intensity modulated radiotherapy for primary tumors of advanced non small cell lung cancer: A multicenter retrospective analy sis based on propensity score matching
Authors: Liu Jie Nhan , Li Tao , Wang Xiaohu Nhan , Su Shengfa , Li Qingsong , Geng Yichao , Yang Wengang , Chen Xiaxia , Ouyang Weiwei , Zhang Wei , Lu Bing
Published: January 2024

In the earlier published article, the affiliations of the first author were not completely provided. The correct affiliations are provided above.

 

New citation: Liu J, Li T, Wang X, Su S, Li Q, Yang W, et al. Volumetric-modulated arc therapy as an alternative to intensity-modulated radiotherapy for primary tumors of advanced non-small-cell lung cancer: A multicenter retrospective analysis based on propensity score matching. Trop J Pharm Res 2022; 21(10):2233-2240 doi: 10.4314/tjpr.v21i10.26  Erratum: 2023; 22(11): 2415 doi:10.4314/tjpr.v22i11.23

 

Earlier citation: Liu J, Li T, Wang X, Su S, Li Q, Yang W, et al. Volumetric-modulated arc therapy as an alternative to intensity-modulated radiotherapy for primary tumors of advanced non-small-cell lung cancer: A multicenter retrospective analysis based on propensity score matching. Trop J Pharm Res 2022; 21(10):2233-2240  doi: 10.4314/tjpr.v21i10.26
Investigation into Online English Learners’ L2 Motivation Using Imagery and Online Counselling Sessions
Authors: Bae Yeonsuk , Lee Eun-Hye
Published: January 2024

In this study, a motivational program using imagery and online counselling sessions was designed based on the theory of the L2 Motivational Self System. This study aimed to investigate the effectiveness of the program by conducting a mixed-method approach, 50 participants took part in 7 imagery training sessions and a pre-post survey. Additionally, among these participants, 20 also engaged in 2 online counseling sessions and focus group interviews. The motivational program using imagery and online counseling sessions was seen to have a significant positive effect on students' L2 Motivational Self System. In particular, as a result of comparing the average values of the pre-post questionnaire, the biggest changes were shown in the categorizes of Ideal Self, Imagery and Visualization, and Attitudes toward Learning English. By utilizing imagery training and online counselling sessions along with English learning, not only were the students' capability of visualizing the image of themselves enhanced, but also positive attitudes towards English education were induced. This led to the fostering of students' motivation in learning English and to the improvement of their L2 Ideal Self Image. Of significant note are the findings in the qualitative data analysis, which show that emotional difficulties in students' English learning, such as academic stress and anxiety, can be alleviated through online counseling sessions, thereby helping them to sustain their learning motivation, Implications of the study are presented and discussed.
A Qualitative Study on the Empathy Formation Process of Nursing Students Participating in Small Group Discussion Classes
Authors: Yun Soojin , Kim Youngsoon
Published: January 2024

The purpose of this study is to explore the process of forming empathy shown in the experiences of participating in small group discussion classes of nursing students, who are the main caring subjects in a multicultural society. To this end, the researcher participated as a teaching assistant in the ‘Multicultural Society and Humanities of Coexistence’ class, which is a required liberal arts course in the nursing department of I University. The research participants were five students who voluntarily expressed their intention to participate after the class. The transcripts of the interviews, each class reflection journal, and midterm and final exams were collected as data. Data analysis analyzed the collected data inductively and analyzed it from the viewpoint of the empathy formation process. As a result of the study, responses such as ‘recognizing differences and experiencing conflict’, ‘discussion became smoother through mutual respect’, ‘my perspective changed through various perspectives’, and ‘practice for coexistence’ were signified by themes. These results suggest that the value of empathy is extended to multicultural acceptance through the process of forming empathy through small group discussion classes, contributing to the practice of coexistence.
A Case Study of Experience-Based Liberal Arts Curriculum Converging Music Listening and Philosophical Thinking
Authors: Lee Irene Eunyoung
Published: January 2024

For current college students and later generations, it was natural to communicate through digital network-based smart media from childhood. Furthermore, amid the COVID-19 era, they became more familiar with the non-face-to-face communication culture in their daily lives. In the future, when they act as the main contributors of society, the advanced AI technology will replace human work more than it has already. Thus, this future social environment makes us recognize the crisis of human dominance, competitiveness, and the loss of our humanity. It is no wonder then that there is a growing voice among educators to emphasize teaching students to strengthen their creativity, communication, and collaboration skills, and to enhance their human emotional intelligence. The purpose of this paper is to present a course example of how to cultivate feeling, intuition, insight, and thinking for ordinary college students in the university with the aim of fostering learners' humanity, emotions, and creativity. In other words, this study introduces examples of designing, operating, and improving a new convergent general elective college course that combines the experience of art appreciation through music listening and the conceptual learning of ideas in the fields of art and philosophy as a class model for holistic education. After operating the first semester in face-to-face lectures, the teaching method was revised to combine face-to-face and non-face-to-face lectures, otherwise known as “Blended Learning”. After running the second semester of a revised curriculum, analysis of this study was conducted to derive educational meaning and values out of the two courses by identifying and comparing the class reactivity, quality, and artistic characteristics of each semester. It is believed that some educational utility and teaching implications obtained in the process of improving and operating these subject designs will prove useful as a reference for course model design and experience-oriented evaluation of some experience-based art elective subjects.
The KAGEDU : Its History, Structure, and Domestic and International Academic Exchange Activities
Authors: Hong Seok Min
Published: January 2024

This paper first examines the history and development of the Korean Association of General Education (hereafter KAGEDU, 2006), which represents the Korean liberal/general education community, in the context of its close relationship with the Korean Council for University General Education (hereafter KCUGE, 2001) and the Korea National Institute for General Education (hereafter KONIGE, 2011). It then examines in detail the number and characteristics of the KAGEDU's members as well as its constituent organizations, operating principles, and the interrelationships among them. Next, this paper finds that the KAGEDU’s The Korean Journal of General Education (hereafter KJrGE, 2007), a first-class academic journal recognized by the NRF (National Research Foundation) of Korea, is a unique national academic journal in Korea that encompasses all aspects of liberal/general education. It is an outstanding leader in terms of publication frequency, number of published articles, and influence index, dominating its field. As a result, the Journal serves as the best public platform for liberal/general education in Korea. This paper also deals with the main features of the KAGEDU's domestic academic activities (Spring and Fall National Conferences, LACs, Seminar 21, Publication of ‘Collected Works of Liberal Education Classics,’ and Selection of Excellent Books) and its activities for international academic exchange (holding international forums and conferences, Blue Waves Lectures, and Libeducols). In particular, it explains that the KAGEDU initiated the establishment of the Asian Liberal Education Network (ALEN) and the holding of the first Asian Liberal Education Conference (ALEC) in late 2023. According to this paper, the two academic events symbolize a very significant outcome of the joint Asian international academic exchange efforts that the KAGEDU, as the hub for liberal education in East Asia, has been leading since 2018. Finally, this article examines the challenges facing the KAGEDU in terms of the ambivalent effects of its relationship with the KCUGE and the KONIGE, its financial independence, modernization of its administration, its under-researched areas, and its need to nurture the next younger generation of scholars. Then, it proposes measures to promote international academic exchange including the establishment of a common Asian liberal education university/college.
The Effects of University Students' Team Efficacy on Learning Engagement and Learning Outcomes in Team-Based Learning of General Education
Authors: Sim Hwayoung , Kim Sehyun
Published: January 2024

The purpose of this study is to examine the effects of team efficacy on learning engagement and learning outcomes in team-based learning. For this purpose, we analyzed class cases conducted through team-based learning at C University's College of General Education. To achieve our purpose, the results of team efficacy, learning engagement, and learning outcomes of 130 learners who experienced team-based learning were analyzed. As a result of the study, first, from analyzing the correlation between team efficacy, learning engagement, and learning outcomes, we found that there was a significant positive correlation between the differences among the three variables. Second, in team-based learning, team efficacy had a positive effect on learning engagement and learning outcomes. Third, from analyzing whether there were differences in team efficacy, learning engagement, and learning outcomes by gender and field in team-based learning, we found that female students partook in higher learning engagement than their male counterparts. However, we also found the same statistically significant difference between female and male students in regards to their majors, as the data showed that female students enrolled in the humanities scored higher when it came to their learning engagment, but not as high as male students taking science and engineering courses. Based on the results of this study, we suggest that systematic instructional design is needed to promote the formation and development of team efficacy in order to increase learner engagement in team-based learning and to maximize learning outcomes.
Humanity Education as Liberal Arts Education Through the Operation of University Students Overseas Volunteer Activities
Authors: Lee Jae-Hyun
Published: January 2024

In the 21st century era of science and technology, the importance of humanity education is becoming more prominent. Humanity education is mainly conducted by the person in charge of liberal arts education at any given university. Among humanity education as liberal arts education, this thesis focused on subjects related to university student volunteer activities and non-subject activities. Volunteer work often stems from spontaneity. However, the reality is that in the Korean educational field, volunteer work is regarded as either an anti-arbitrary and compulsory activity allowing for the attainment of favorable scores for university entrance exams, or to meet university graduation requirements. However, it should not be overlooked that service can be strengthened through education and training, and spontaneity can be established. In this respect, overseas volunteer activities for university students can be said to be a very important extracurricular endeavors when it comes to training the basic training of services, such as sharing and serving and cultivating the leadership of serving. In this paper, the actual operation of overseas volunteer activities through Dongduk Womens University and a university council called the Korean University Council For Social Service were examined as humanity education for university students. In addition, in this study we examined how volunteer work has a positive effect on individual character growth and humanity education of university student volunteers. We also confirmed that university students overseas volunteer activities are very useful educational tools for the development of humanity education, which functions as one of the pillars of liberal arts education.
Transformation and Expansion of Liberal Education in Japanese Universities : With the Activities of the Japan Association for College and University Education
Authors: Toru Hayashi
Published: January 2024

The generalization of the Standards for the Establishment of Universities in 1991 was an important turning point in transformation process for general education of Japanese Universities. Following the 1991 introduction of the general standards for the establishment of universities and the 2012 qualitative shift in university education (especially the spread of active learning), Japanese university education is currently facing the third wave of the education that integrates humanities and sciences, and STEAM education. As this approach to human resource development is about to undergo a major shift, Japanese opinion leaders have presented the basic liberal arts in the new era.The Liberal and General Education Society of Japan, founded in 1979, changed its name to the current Japan Association for College and University Education in 1997. It has been active for more than 40 years while increasing its membership. The Association’s history has been influenced by major changes in Japanese university education since the 1990s.As good examples of undergraduate and graduate education reforms emphasizing Liberal Education, Kanazawa University has been reforming its educational system based on the concept of interdisciplinary integration and collaboration among different fields. The key point of Kanazawa University’s efforts to reorganize the curriculum for liberal and common education is that, in undergraduate courses, opportunities to cultivate a broad range of cultures and diverse perspectives has been established in the liberal arts and common education courses to develop the learning strength for specialized education.Liberal education is an important theme related to the raison d’etre of the university. In this borderless era, we believe that it is time to objectively look at the current state of liberal education in our countries and improve it through further enhancing comparative research in South Korea, Taiwan, and Japan on the theme of liberal education.
Near chromosome-level and highly repetitive genome assembly of the snake pipefish Entelurus aequoreus (Syngnathiformes: Syngnathidae)
Authors: Wolf Magnus , Ferrette Bruno Lopes da Silva , Coimbra Raphael T. F. , de Jong Menno , Nebenführ Marcel , Prochotta David , Schöneberg Yannis , Zapf Konstantin , Rosenbaum Jessica , Mc Intyre Hannah A. , Maier Julia , de Souza Clara C. S. , Gehlhaar Lucas M. , Werner Melina J. , Oechler Henrik , Wittekind Marie , Sonnewald Moritz , Nilsson Maria A. , Janke Axel , Winter Sven
Published: January 2024

The snake pipefish, Entelurus aequoreus (Linnaeus, 1758), is a northern Atlantic fish inhabiting open seagrass environments that recently expanded its distribution range. Here, we present a highly contiguous, near chromosome-scale genome of E. aequoreus. The final assembly spans 1.6 Gbp in 7,391 scaffolds, with a scaffold N50 of 62.3 Mbp and L50 of 12. The 28 largest scaffolds (>21 Mbp) span 89.7% of the assembly length. A BUSCO completeness score of 94.1% and a mapping rate above 98% suggest a high assembly completeness. Repetitive elements cover 74.93% of the genome, one of the highest proportions identified in vertebrates. Our demographic modeling identified a peak in population size during the last interglacial period, suggesting the species might benefit from warmer water conditions. Our updated snake pipefish assembly is essential for future analyses of the morphological and molecular changes unique to the Syngnathidae.
Resenha do Livro – Sinfonia inacabada: a política dos comunistas no Brasil
Authors: Figlino Anna Paula
Published: January 2024

Resenha do Livro:

MAZZEO, Antonio Carlos. Sinfonia Inacabada: a política dos comunistas no Brasil. 2ª edição. São Paulo: Boitempo, 2022.
Editorial
Authors: Abad Seminario Víctor
Published: January 2024

Luego de varios meses de marcado esfuerzo, nos complace presentar a nuestros lectores el octavo número de Giuristi: Revista de Derecho Corporativo, que cierra su cuarto año desde que fue fundada en el 2020, y cuyo primer número fue publicado en junio de ese mismo año. Este nuevo ejemplar refleja el empeño de una parte importante de profesores y personal administrativo a cargo de la edición y publicación de la revista, la cual se ha convertido en un elemento de vital importancia para el desarrollo de la carrera de Derecho Corporativo en la Universidad ESAN, que se continúa afianzando en el mercado jurídico como un líder del sector.
Una peculiar visión del derecho. ¿y si por unos minutos nos apartamos de Kant y nos aproximamos a Nietzsche?
Authors: Da Giau Roose Piero
Published: January 2024

El presente trabajo expone reflexiones sobre la vinculación entre el derecho con la sociología, la ética, la moral, la religión, la literatura y la filosofía; y en laza los conceptos jurídicos —asumidos a priori— en su acepción no filosófica. Plantear cuestionamientos derivados de otras ramas del saber humano nos permitirá asumir y entender el carácter multidisciplinario del derecho, par tiendo de situaciones jurídicas que se contrastan con el campo eminentemente sociológico. Asimismo, reflexionaremos sobre asuntos religiosos, morales y éticos, a las luces de la filosofía que todo lo cuestiona —en especial, una visión nietzscheana— y desde el enfoque de la literatura, que todo lo aborda.
Cuando el derecho procesal y el arbitraje se encuentran*
Authors: Pulido Del Pino Natalí Juliana
Published: January 2024

El presente artículo es una reflexión que, valiéndose de la doctrina y la juris prudencia, tiene como finalidad evaluar qué ocurre con la determinación de la competencia cuando estamos ante cláusulas patológicas. Si bien, en principio, deberíamos remitirnos a la vía arbitral, en algunos casos excepcionales las controversias terminarán siendo dirimidas por el Poder Judicial. Para tales efectos, partimos desde el concepto de la cláusula arbitral; luego, trataremos la excepción del convenio arbitral, donde se desarrollan los tipos de patologías que se pueden encontrar; y analizaremos qué ha pasado, en la práctica, en las cortes nacionales peruanas, para finalmente determinar quién será la autoridad competente en cada caso concreto.
Desarrollo sostenible en las empresas del Perú: ¿voluntario u obligatorio?
Authors: Ruiz Vásquez Úrsula Patricia
Published: January 2024

El objetivo de este artículo es determinar si el cumplimiento del concepto de desarrollo sostenible, por parte de las empresas del Perú, es voluntario u obligatorio, a partir de la revisión detallada de bibliografía relacionada a responsabilidad social corporativa, memorias o reportes de sostenibilidad, empresas con certificación B y sociedad BIC; así como del análisis de diversas sentencias del Tribunal Constitucional acerca de algunos de estos conceptos y de nuestro régimen de economía social de mercado.
A partir de los resultados del citado análisis, será posible determinar que las empresas peruanas, además de generar rentabilidad económica, necesitan incorporar dentro de su gestión los componentes social y ambiental, a través de acciones absolutamente medibles, comprobables y sostenibles que contribuyan a que las generaciones presentes y futuras del país puedan gozar de una vida digna.
Análisis jurisprudencial de la introducción del derecho penal del enemigo en delitos económicos
Authors: Ahomed Omar
Published: January 2024

El objetivo del presente análisis es identificar cómo los tribunales de justicia peruanos emplean elementos del derecho penal del enemigo para resolver delitos económicos. Para ello, se examina la incorporación de algunos aspectos distintivos del derecho penal que los tribunales de justicia peruanos están utilizando en la resolución de delitos económicos, con el fin de demostrar cómo los principios clásicos del derecho penal del ciudadano, como son la mínima intervención, la lesividad y la presunción de inocencia, son limitados en delitos económicos mediante el derecho penal del enemigo.
El artículo tiene trascendencia social porque aborda la justicia pedida por agentes económicos, usuarios y consumidores para lograr las condiciones básicas de seguridad ciudadana en las que puedan desarrollar sus actividades económicas.
Lessons from the past for future directions
Authors: Topliceanu Stefan Catalin
Published: January 2024

Migration is a continued process that causes both positive and negative effects. This study investigates the EU’s resilience to migration challenges taking into consideration a comparative analysis of the European refugee crisis of 2015 and the influx of refugees from Ukraine due to the Russian invasion. On the one hand, the European refugee crisis of 2015 raised doubts about the EU’s ability to manage a humanitarian crisis, highlighting the necessity for enhancing its crisis management. However, the EU learned valuable lessons from that crisis, leading to a decrease in illegal border crossings and an improvement of its ability to anticipate future im migration patterns, and its resilience against migration challenges.
The economic impact of international travelers in the hospitality industry of Austin, Texas, USA in 2021: a regional input-output and data visualization approach
Authors:   Colorado Mountain College, Steamboat Springs, Colorado, USA, Perez Pena Rafael Perez
Published: January 2024

The purpose of this paper is to estimate the economic impact of departing international flights in the hospitality industry and other related industries of Austin, Texas, USA in 2021 using an input-output approach and to present the results using data visualization tools. The estimated total economic impact of the international flights departing from Austin, Texas in its economy is around $77 million USD in business sales. The total impact is comprised by the direct, indirect, and induced effects in the regional economy. The indirect and induced effects are estimated to be $26 million in output and a direct effect of $51 million. These estimates imply an estimated output multiplier of 1.6. For every $100 USD spent in the air passenger industry, $60 additional USD are generated due to related industries to the air transportation industry. While the literature on regional economic impact of the hospitality industry is extensive, this paper intends to present a holistic and integrated approach by attempting to present a bridge between travelers’ sentiments, patterns in preferences, and the economic impact of international flight in the regional economy.
Sentiment analysis of reviews of spa hotels in Serbia
Authors:   University of Novi Sad, Faculty of Science, Department of Geography, Tourism and Hotel Management, Serbia, Tepavčević Jelena , Blešić Ivana ,   University of Novi Sad, Faculty of Science, Department of Geography, Tourism and Hotel Management, Serbia, Vučenović Danijel
Published: January 2024

An important but underutilized new resource for gathering input on customer experience for the hospitality industry is consumer reviews posted on Internet travel portals. These data are frequently large and unstructured, which makes analysis difficult for conventional techniques because they were made for well-structured, quantitative data. Data obtained from customers can be used to assess satisfaction and dissatisfaction, with the aim of improving hotel services. Spa hotels offer an exclusive experience for their guests by offering plenty of additional services such as pools, saunas, massages, and various treatments. This research focused on examining textual online reviews of spa hotels in Serbia. A total of 20 hotels were included in the research, with 319 online reviews to be processed. Word frequency analysis, sentiment analysis, and analysis of the distribution of helpful votes were performed. Considering that spa hotels offer their guests specific services, by analyzing the frequency of words, key words that describe the services and experience in spa hotels were singled out. Sentiment analysis showed that there are no extremely negative sentiment values, which indicates a lower presence of negative feelings, but the highest sentiment value does not indicate the presence of extremely positive feelings either. By performing an analysis of helpful votes in reviews, it was found that the majority of reviews are not classified as helpful.
The development of circular economy in Western Balkan countries
Authors:   University of Belgrade, Faculty of Economics and Business, Belgrade, Serbia, Mitrović Đorđe , Pešalj Biljana ,   Rotterdam University of Applied Sciences, Rotterdam Business School, Netherlands
Published: January 2024

The circular economy implies that the primary source of economic growth is the maximum reuse of many materials obtained from products at the end of their life cycle and the minimum extraction of new resources. In contrast to it, the traditional linear economy follows a simple path “take - produce - dispose”, i.e., it is based on the constant extraction of new resources and the disposal of used products as waste without the possibility of their reuse as inputs in the production of the same or another product. In Western Balkans countries, this paper reviews the degree of progress made in developing Circular Economy. The efficiency of Western Balkan countries when it comes to developing and implementing a circular economy will be demonstrated in the DEA analysis. The key trends in the evolution of circular economies in the Western Balkan countries, as well as the most important elements hindering its faster development and mutual convergence with the countries of European union will be highlighted in this paper.
Impact of the COVID-19 pandemic on international freight transport in Slovenia and EU
Authors:   University of Maribor, Faculty of Logistics, Slovenia, Rosi Maja , Škrjanec Gabrijela ,   University of Maribor, Faculty of Logistics, Slovenia, Rosi Bojan ,   University of Maribor, Faculty of Logistics, Slovenia
Published: January 2024

The sudden emergence of COVID-19 and the declaration of a pandemic in the year 2020 has significantly impacted all factors of the economy, including international trade of goods. International freight transport (road, rail, air, and maritime) was also affected. The research analyses the changes in the implementation of international freight transport during the COVID-19 pandemic in EU countries. The main research question was: How did the COVID-19 pandemic impact international freight transport in Slovenia and selected EU member countries? According to the results, we can see that the pandemic outbreak had a different impact on each type of transport. Some modes of transport were more negatively affected by the pandemic than others. In the case of international road freight transport, the pandemic positively affected it (both in Slovenia and at the EU level) since the volume of transported goods increased.
The impact of TikTok on travel decision
Authors:   University of Kragujevac, Faculty of Hotel Management and Tourism in Vrnjačka Banja, Dramićanin Sandra , Perić Goran ,   Toplica Academy of Applied Studies, Department of Business School Blace, Serbia, Gašić Marko ,   Toplica Academy of Applied Studies, Department of Business School Blace, Serbia
Published: January 2024

Social media is becoming an essential source of travel information for potential travelers. By using the functions of social networks, identifying the target audience, and creating exciting content, tourism offer holders can promote the offer and activities to a broader audience and cultivate meaningful relationships with potential and loyal users. Offer holders in modern business must accept the opportunity that TikTok, as currently the most visited social network, offers and add this platform to their marketing strategies on social networks. TikTok's influence on the travel industry is growing, with tourists increasingly turning to the platform to find travel inspiration, discover their next vacation destination, or plan their next trip. The paper explores TikTok’s impact on tourists' travel decisions. People from the millennials (1980-1994) and the Z generation (1995-2009) in the Republic of Serbia represent 113 respondents. The analysis results show significant differences in the factors influencing the decision to travel according to the age structure of respondents who use TikTok. This paper enriches existing domestic and foreign research on the topic of tourists' travel decision-making based on the use of social networks. The results of this research can help tourism offer owners use TikTok and short videos more effectively to promote their offer.
The evolving interaction between traditional marketing channels and the digital age
Authors:   Toplica Academy of Applied Studies, Department of Business Studies Blace, Serbia, Zlatanov Sonja , Đuričanin Jasminka ,   Toplica Academy of Applied Studies, Department of Business Studies Blace, Serbia
Published: January 2024

In an era defined by digital transformation, this paper investigates the enduring impact of traditional marketing channels on consumer behavior within contemporary markets. It investigates the complex interaction between traditional marketing channels and the digital age, considering how these channels persist and adapt in the era of digitalization. A group of 248 respondents from Serbia participated in a questionnaire-based study, capturing engagement, preferences, and interactions with messages sent via traditional marketing channels. The study investigates how engagement levels are affected by factors such as recalling traditional marketing messages and engaging in digital actions following exposure. The results showed that traditional marketing remains relevant, with television commercials and print advertisements being encountered and recalled most frequently.
Compromiso organizacional en la gestión administrativa de la Universidad Nacional Hermilio Valdizán, Huánuco, Perú
Authors: Pillco Primo Susan Carol
Published: January 2024

Objetivo. El estudio buscó evaluar la influencia del compromiso organizacional en la gestión del personal administrativo de la Universidad Nacional Hermilio Valdizán, Huánuco, 2022. Métodos. El tipo de estudio fue aplicado, de nivel explicativo y diseño no experimental - transversal. La muestra quedó constituida por 30 trabajadores administrativos y fue obtenida por muestreo no probabilístico de tipo intencional, teniendo en cuenta los criterios de selección. Se utilizaron dos instrumentos para la recolección de datos; el primero fue el inventario de compromiso organizacional, con 21 preguntas, y el segundo fue el cuestionario para la gestión administrativa, con 40 preguntas. Ambos fueron validados por el juicio de expertos para determinar su validez de contenido y se aplicó el coeficiente alfa de Cronbach para determinar la confiabilidad, obteniendo un índice de 0,985 para el instrumento de compromiso organizacional y de 0,988 para el instrumento de gestión administrativa. Resultados. Los resultados muestran un compromiso organizacional saludable en un 90 %, una gestión administrativa excelente en un 49 % y una relación entre las variables de un nivel alto con 97,2 %. Debido a que p = 0,000 < 0,05 y r = 0,972, se aceptó la hipótesis del estudio. Conclusión. En relación al objetivo general se determinó que el compromiso organizacional influye en la gestión administrativa del personal administrativo de la Universidad Nacional Hermilio Valdizán, Huánuco, 2022, ya que existe entre las variables una relación en un nivel alto con 97,2 %.
Predictors of Mortality in Acute Coronary Syndrome Patients: A Literature Review
Authors: Azzahra Fadhila Nafilah , Adnan Nurhayati
Published: January 2024

Acute coronary syndrome (ACS) is a serious medical condition that includes myocardial infarction and unstable angina. This study aimed to determine the factors that can predict mortality in ACS patients. This study used qualitative research methods. Data collection techniques in this study use literature study research methods obtained from Google Scholar. The data that has been collected in this study is then analyzed using three stages, namely data reduction, data presentation and conclusions. The results showed that Acute Coronary Syndrome (ACS) occurs because the coronary arteries experience the thickening of lipid plaques and can develop into Unstable Angina Pectoris (UAP), Non-ST Elevation Myocardial Infarction (NSTEMI), or ST Elevation Myocardial Infarction (STEMI). Risk factors involve age, sex, smoking, dyslipidemia, diabetes, hypertension, and obesity. Symptoms of Acute Myocardial Infarction (IMA) include chest pain, shortness of breath, and fatigue. Prognosis is influenced by treatment speed, left ventricular ejection fraction (FEVKi), and risk factors for comorbidities. Initial therapy of MONACO (Morphine, Oxygen, Nitrate, Aspirin, Clopidogrel/Ticagrelor) with statins. Administration of anticoagulants and reperfusion measures such as fibrinolysis or percutaneous coronary intervention (IKP) is important. Therapy options are adjusted to risk factors to improve prognosis.
Dataset of U.S. School Bus Depots
Authors: Shao Yang , Lazer Leah , Taff Gregory
Published: January 2024

This technical note describes the methods used to create a dataset of school bus depot locations in the United States. There are nearly half a million school buses in the country but almost no public information about where they are kept. Environmental justice literature describes how school bus depots may create air pollution hotspots for underserved communities that lead to health harms and may require grid infrastructure upgrades for future bus electrification.
Investigation of Some Autosomal Recessive Inherited Diseases (BLAD, DUMPS, CVM, and FXID) in Holstein Cattle
Authors: TÜRKMEN Döne , DEMİR Eymen , BİLGİNER Ümit , KARSLI Taki
Published: January 2024

Genetic disorders are often transmitted via autosomal recessive inheritance, which negatively affect health, welfare, and yield traits in farm animals such as cattle. In this study, a total of 80 animals belonging to Holstein Friesian (HF) reared in the dairy farm of Akdeniz University were investigated in terms of Bovine Leukocyte Adhesion Deficieny (BLAD), Deficiency of Uridine Monophosphate Synthase (DUMPS), Factor XI Deficiency (FXID), and Complex Vertebral Malformation (CVM) via three molecular genotyping methods such as Polymerase Chain Reaction (PCR), PCR-Restriction Fragment Length Polymorphism (PCR-RFLP), and Allele-Sprcific PCR (AS-PCR). BLAD and DUMPS were analysed by PCR-RFLP, while PCR and AS-PCR were utilized to investigate FXID and CVM disorders, respectively. Based on fragment patterns on agarose gel electrophoresis, animals were genotyped as normal, mutant, and carrier. In this study, no carrier or mutant animals were detected for BLAD, CVM, DUMPS, and FXID diseases in HF cattle, since these animals were previously imported from disease-free dairy farms located in different provinces of Türkiye. Nevertheless, this population should be periodically checked for autosomal genetic disorders, since inherited diseases may be observed in the next generations due to causative mutations in the related genomic regions.
Pengaruh Pemberian Tepung Daun Talas (Colocasia esculenta L) dalam Ransum Terhadap Bobot Karkas dan Persentase Karkas Itik Mojosari
Authors: Johan Johan , Kadir Muhammad Jurhadi , Rasbawati Rasbawati
Published: January 2024

Penelitian ini bertujuan untuk mengetahui pengaruh penambahan tepung daun talas (Colocasia esculenta L.) dalam ransum terhadap bobot karkas dan persentase karkas itik Mojosari. Penelitian ini menggunakan rancangan acak lengkap (RAL) dengan 4 taraf perlakuan dan 3 ulangan. Perlakuan yang digunakan yaitu P0: (kontrol) tanpa perlakuan, P1 : pakan ternak itik + 1 % tepung daun talas, P2 : pakan ternak itik + 3 % tepung daun talas, P3 : pakan ternak itik + 5 % tepung daun talas. Berdasarkan hasil yang didapat maka diketahui bahwa penambahan tepung daun talas pada pakan menunjukkan berpengaruh sangat nyata (P<0.01) terhadap bobot karkas dan persentase karkas itik Mojosari. Adapun perlakuan terbaik pada perlakuan P3 dengan penambahan tepung daun talas 5 %.
Uji Kualitas Fisik Es Krim dengan Penambahan Tepung Bunga Telang (Clitoria ternatea L.)
Authors: Yusmaniar Yusmaniar , Faridah Rajmi , Hermawansyah Hermawansyah
Published: January 2024

Perkembangan penerapan bunga telang (Clitoria ternatea L.)  pada pengolahan makanan belum banyak dimanfaatkan. Upaya yang mungkin dilakukan adalah penggunaan bunga telang sebagai pewarna biru alami dalam produksi es krim. Penelitian ini bertujuan untuk mengetahui pengaruh penambahan tepung bunga telang  terhadap nilai fisik (overrun dan resistensi pelelehan) es krim.  Penelitaian ini menggunakan Rancangan Acak Lengkap (RAL) dengan 4 perlakuan (0%, 5%,10% dan 15% penambahan tepung bunga telang) dan 3 kali ulangan. Parameter yang diukur yaitu overrun dan resistensi pelelehanHasil penelitian menunjukkan bahwa penambahan tepung bunga telang pada es krim berpengaruh sangat nyata (P<0.01) terhadap overrun dan resistensi pelelehan. Nilai overrun dan resitensi tertinggi pada perlakuan yaitu pada penambahan 15% tepung bunga telang. Kesimpulan penelitian ini yaitu peningkatan konsentrasi penambahan tepung bunga telang dalam pembuatan es krim menyebabkan overrum es krim bunga telang meningkat dan memperlambat daya lelehnya.
Mekanisme dan Manfaat Kompresi Dingin dalam Pengobatan Segera Cedera Jaringan Lunak
Authors: Rafyansyah Albany , Ardiansyah Daffa , Agatha Syahnoeran Putra
Published: January 2024

Olahraga merupakan gerakan yang menggunakan berbagai struktur pada tubuh manusia, seperti sendi, otot, meniscus/discus, kapsuloligamenter, dan otot. Oleh karena itu, risiko cedera pada saat berolahraga tidak dapat dihindari. Jika cedera tidak diperoleh dengan cepat dan tepat, dapat menyebabkan gangguaan keterbatasan terhadap fisik, dalam aktivitas sehari-hari maupun olahraga terkait. Jenis cedera dapat dikelompokkan menjadi cedera langsung, cedera tidak langsung, cedera karena penggunaan berlebihan, cedera jaringan keras, dan cedera jaringan lunak. Cedera ini melibatkan kulit, otot, tendon, dan ligamen. Oleh karena itu, penanganan cedera harus dilakukan dengan cermat, dan terapi serta rehabilitasi yang sesuai harus diterapkan. Salah satu alternatif pengobatan yang sederhana adalah menggunakan kompresi dingin. Dalam konteks ini, penulis akan menjelaskan manfaat penggunaan kompresi dingin dalam pengobatan cedera pada jaringan lunak.
UTILIDADES DE LA ESPIRONOLACTONA COMO FÁRMACO ANTIANDROGÉNICO
Authors: Teruel Ginés Rolando , Leyva Montero María de los Ángeles , Tamayo Calle Ana Victoria , Minda Valverde Itaty Jaelinne , Morales Freire Kevin Fernando
Published: January 2024

Introducción. La espironolactona es un medicamento utilizado principalmente como diurético ahorrador de potasio, ya que actúa como antagonista competitivo de los receptores de los mineralocorticoides, pero también puede ser utilizado como agente cardiovascular, agente endócrino metabólico y como antiandrógeno. Objetivo. Describir otras acciones farmacológicas de la espironolactona desde su acción antiandrogénica. Metodología. Revisión bibliográfica de tipo narrativa realizada. Se incluyó la información de libros, artículos científicos, revisiones y tesis acerca de la espironolactona y sus otros posibles usos en enfermedades tegumentarias, utilizando bases de datos como: medicap, Medscape, Medigraphic, SciELO, entre otras; además. Se utilizaron distintas revistas como la revista nefrológica, revista Urología y Nefrología, entre otras. Resultados. Se encontraron 46 fuentes de información de los cuales 2 son libros de farmacología y 44 artículos científicos de los cuales solamente se utilizaron 33 referencias que contenían la información necesaria y cumplían con los criterios de selección. Discusión: La acción de la espironolactona debida a sus características antiandrogénicas puede utilizarse en el tratamiento para la alopecia androgénica, hirsutismo y acné, ya que este va a actuar sobre los receptores de andrógenos periféricos inhibiendo la 5α-reductasa, 17α-hidroxilasa y la 17,20-liasa. Conclusión: La espironolactona es un medicamento seguro y eficaz para el tratamiento enfermedades dermatológicas como la alopecia androgénica, acné e hirsutismo ya sea en monoterapia o combinado con otros medicamentos. Sin embargo, se debe prestar atención a los efectos adversos y contraindicaciones que este posee.