bluuebunny/crossref_metadata_2025 huggingface dataset:
The Hemoglobin-to-Red Cell Distribution Width Ratio to Predict All-Cause Mortality in Patients with Sepsis-Associated Encephalopathy in the MIMIC-IV Database
Authors: Huang Xiaxuan , Yuan Shiqi , Ling Yitong , Tan Shanyuan , Huang Tao , Cheng Hongtao , Lyu Jun
Published: January 2023

Objective. The hemoglobin-to-red cell distribution width ratio (HRR) is associated with the prognosis of sepsis-associated encephalopathy (SAE). This study aimed to determine the relationship between HRR and SAE and to clarify the possible mechanism of HRR as a prognostic factor for SAE. Methods. A multivariate Cox proportional-hazards regression model was used to assess the correlation between HRR and all-cause mortality. Piecewise linear regression and smooth-curve Cox proportional-hazards regression models were used to observe whether there was a nonlinear relationship between HRR and all-cause mortality in SAE. Results. This study included 8853 patients with SAE. A nonlinear relationship between HRR and SAE was observed through a two-segment regression model. The left inflection point for the HRR threshold was calculated to be 15.54, which was negatively correlated with all-cause mortality (HR = 0.83, 95% CI = 0.76–0.91,

p
<
0.001

). Subgroup analyses revealed significant interactions between white blood cell count, glucose, and patients who received dialysis and HRR. The inverse correlation between HRR and SAE was more pronounced in patients who did not receive vasopressin (HR = 0.91, 95% CI = 0.87–0.96,

p
<
0.001

) than in those who did receive vasopressin (HR = 0.94, 95% CI = 0.88–1.02,

p
=
0.152

) and was significantly more pronounced in patients without myocardial infarction (HR = 0.91, 95% CI = 0.88–0.96,

p
<
0.001

) than in those with myocardial infarction (HR = 0.94, 95% CI = 0.87–1.02,

p
<
0.114

). Conclusion. This large retrospective study found a nonlinear relationship between all-cause mortality and HRR in patients with SAE in intensive care units, with low HRR being inversely associated with increased all-cause mortality in patients with SAE.
Antiacne and Anti-Inflammatory Effects of Phenolic Compounds from Quercus acutissima Carruth. Leaves
Authors: Kim Eun Bin , Lee Eun Kyung , Son Se Yeon , Lee Min Won
Published: January 2023

Quercus plants are widely distributed in Korea and have been used for their antiallergic and anti-inflammatory properties to treat dermatitis. The phenolic compounds of Quercus acutissima Carruth (QA) are estimated to have antioxidant and anti-inflammatory activities, based on the results of previous studies with Quercus mongilica, Quercus stenophylla, Quercus gilva Blame., and Quercus acuta Thunb. We yield QA extract and the isolated phenolic compounds (hyperoside (1), astragalin (2), kaempferol 3–O-(6″- galloyl)–β–D–glucopyranoside (KGG) (3), quercetin 3–O-(6″-O-galloyl)-β–D–glucopyranoside (QGG) (4), pedunculagin (5), and casuarinin (6)) and were identified using NMR. Among them, KGG (3) and QGG (4) were isolated for the first time from QA. QA extract and the isolated phenolic compounds demonstrated antioxidative, anti-inflammatory, and antiacne activities in RAW 264.7 mouse macrophage cells in vitro. 3–6 demonstrated strong inhibitory activities in the DPPH scavenging and NO production assay and anti-inflammatory and antiacne activities through western blotting (NLRP3, IL-1β, and 5α-reductase). The most outstanding activity in all experiments was casuarinin (6). The study findings suggest potential therapeutic candidates for acne.
Egg Freshness Indexes Correlations with Ovomucin Concentration during Storage
Authors: Jiang Yajun , Fu Dandan , Ma Ming
Published: January 2023

The relationship between protein changes and egg quality during storage is a critical area of investigation in both basic science and egg product preservation. Viscosity changes in albumen are a sensitive sign of the deterioration process. Ovomucin, which is present in albumen, plays an important role in the gelation of the albumen. Egg freshness indices and ovomucin concentration will alter in response to storage time. This paper analyzed the correlation and gray relational degree between the Haugh unit (HU), yolk index, albumen pH, and ovomucin concentration. We studied the differences in the ovomucin concentration at different levels of HU, yolk index, and pH during storage. We established an equivalent egg age prediction model using ovomucin concentration as the independent variable. The findings indicated a correlation between the freshness indices and the ovomucin concentration. There was a good, significantly positive relationship between HU and ovomucin concentration (r = 0.713,

P
<
0.01

), a positive correlation between the yolk index and ovomucin concentration (r = 0.699,

P
<
0.01

), and a negative correlation between albumen pH and ovomucin concentration (r =  −0.683,

P
<
0.01

). The highest Pearson correlation coefficient (r = 0.970,

P
<
0.01

) was obtained between the albumen and ovomucin concentration. Significant differences in ovomucin concentration were observed when HU, yolk index, and pH were varied. The gray relational degree between each freshness parameter and ovomucin concentration was greater than 0.8. Between the HU and ovomucin concentration, there was a gray correlation degree of 0.885, indicating that the HU was the primary factor affecting ovomucin concentration variation during storage. During storage, at 22°C, the ovomucin concentration in albumen was significantly and negatively related to storage time (r = −0.926,

P
<
0.05

). The coefficient of determination for the equivalent egg age prediction model with ovomucin concentration as the independent variable was 0.985 (

P
<
0.05

), indicating strong reliability. The study’s findings show the possibility of nondestructive prediction of an egg’s internal microscopic protein composition using its freshness index value.
Model of physical self-development of girls - future officers in the physical education at the military academy
Authors: Sliusarchuk Victor
Published: January 2023

The conducted research was aimed at designing a model of physical self-development of girls - future officers, which occurs in the process of their physical education during training at the military academy. To achieve this goal, adequate research methods were used, preference was given to general scientific methods, in particular analysis and synthesis, systematization, generalization, and theoretical modeling. Sources of information were selected from scientometric databases Scopus, SPORT Discus, Web of Science, using keywords. The study of information from literary sources proved the formation of readiness of girls - future officers for physical self-development during training at the military academy at a level that differs from the appropriate one. This made it necessary to design an appropriate structural and functional model. Such a model combined methodological, organizational-methodical, functional, diagnostic and evaluation components and adequate pedagogical conditions, criteria, indicators and levels of readiness of girls - future officers for physical self-development during training at the military academy. The projected model is consistent with others available in pedagogical science, but requires experimental verification of its effectiveness in terms of achieving the set goal.
A Review on Cytogenetically Studied Species of Family Coenagrionidae (Odonata: Zygoptera)
Authors: Hallan Harkiran Kaur , Walia Gurinder Kaur , Dhillon Gagandeep Kaur
Published: January 2023

ABSTRACT: Cytotaxonomy is useful for separating sister and cryptic species as well as for figuring out the evolutionary relationship between taxa. Family Coenagrionidae is considered as one of the largest zygopteran families under order Odonata. Globally, a lot of investigation has been undertaken on the family Coenagrionidae and significantly contributed by biologists throughout the world. Type number of the family Coenagrionidae is n=14 with XO-XX type of sex determining mechanism. Karyotypic variations within and between species are observed due to chromosome breaks and fusions, absence/presence of m chromosomes because of the holokinetic nature of chromosomes. Cytogenetically, 107 coenagrionid species have been studied all over the world which also includes 37 species from India. Among these, most of the species possesses n=14 haploid complement, while variation in chromosome number has been observed in 25% species.
Antibacterial and Anti-Quorum Sensing Studies of Extracellularly Synthesized Silver Nanoparticles from Azadirachta indica (Neem) Leaf Extract
Authors: Mishra Rajni , Gwalani Ketki , Nashikkar Nandiata , Bundale Sunita
Published: January 2023

Azadirachta indica (Neem ) is an important medicinal plant with proven strong antiseptic, antiviral, antifungal and antibacterial properties. The study here presents the antibacterial and QS (Quorum Sensing) inhibitory potential of biogenic Silver nanopaticles (AgNPs) from Azadirachta indica leaf extracts. The nanoparticles were synthesized using an aqueous extract of Azadirachta indica leaves and silver nitrate solution. The size, crystal structure, elemental composition and other physical properties of nanoparticles were determined using different microscopic and spectroscopic techniques. The average diameter of the nanoparticles was found to be between 20-43 nm with crystalline morphology. These extracellularly synthesized AgNPs strongly inhibited Gram negative pathogenic species and exhibited demonstrable anti- Quorum Sensing (QS) activity as evident from pigment inhibition and 75- 80% decrease in biofilm mass on AgNPs treatment in a dose dependent manner.
Diversity and Extracellular Enzyme Production of Fungal Endophytes from the Genus Ocimum L.
Authors: Karthika M Karthika M , A. R Rasmi
Published: January 2023

Ocimum tenuiflorum, O. gratissimum, and O. basilicum are medicinal plants extensively used in the traditional medicine of Kerala. The study is aimed at investigating the endophytic mycoflora associated with these Ocimum species and their ability to produce enzymes in vitro. A total of 149 fungal endophytes were isolated from roots, stems, and leaf segments from July to November 2021. They were grouped into 27 morphotypes, including five non-sporulating taxa. The highest number of isolates were obtained from the plant O. basilicum. An equally lower number of isolates were obtained from O. gratissimum and O. tenuiflorum. A greater number of fungal endophytes were obtained from the leaf segments of O.basilicum and least number of isolates obtained from the leaf segments of O.gratissimum. Isolates of Aspergillus niger complex, Diaporthe sp., and Daldinia eschscholtzii showed the highest colonizing frequency. In vitro analysis for enzyme production by all morphotypes was done and, except for laccase, all tested enzymes showed positive results.
Rehabilitation in digital environments – biophysiologically motivated gamification
Authors: Wojciechowski Adam , Korjonen-Kuusipuro Kristiina
Published: January 2023

Nowadays, the process of cognitive or motor rehabilitation is mostly implemented in a traditional form. Paper-pencil cognitive exercises or physical exercises with instruments still dominate over digital environments. However, they require constant supervision by professionals, whose availability is relatively decreasing in an ageing society. Lack of supervision, in turn, results in a loss of motivation to exercise or, at the very least, ineffective, sometimes incorrect, exercise. In addition, traditional rehabilitation mechanisms are often repetitive and tedious. Sometimes a lack of supervision or routine results in a failure to adapt the challenges to the user's current needs.

Digital environments and modern technology have much to offer in this regard. One aspect is gamification mechanisms, which work well in video games and allow players to be engaged for hours in challenges of modulated difficulty. Another aspect is the rapidly developing biosensors and tracking systems that allow the user's activity and biophysiological parameters to be monitored in real time. However, the combination of the benefits of technology and gamification stimulus mechanisms must be done in strict accordance with the user's capabilities in order to make the challenges constructive rather than destructive for the user's body and mental conditions. Ongoing monitoring of effort and mental workload and their synchronization with fatigue in the digital environment, supported by motivational gamification mechanisms, form the foundation of the correct and controlled exercises and rehabilitation.
Bilim Sanat Merkezlerine Devam Eden Özel Yetenekli Öğrencilerin Müdür Kavramına İlişkin Metaforik Algıları
Authors: DOĞAN Ümit
Published: January 2023

Bu çalışma Bilim ve Sanat Merkezlerine devam eden özel yetenekli öğrencilerin ’’Müdür” kavramına yönelik sahip
oldukları algıları metaforlar aracılığıyla ortaya çıkarmak amacıyla yapılmıştır. Çalışma nitel araştırma desenlerinden
olgubilim desenine göre yürütülmüştür. Araştırmanın verileri 2019-2020 eğitim öğretim yılında, Şanlıurfa Bilim ve Sanat
Merkezinde eğitim görmekte olan 24 kız, 30 erkek toplam 54 özel yetenekli öğrenciden toplanmıştır. Veriler,
öğrencilerce “Müdür...….…gibidir. Çünkü……....…” ifadesini tamamlamasıyla elde edilmiştir. Elde edilen bulgulara
göre özel yetenekli öğrenciler “Müdür” kavramı için 54 geçerli metafor üretmiştir. Özel yetenekli öğrenciler tarafından
oluşturulan metaforlar benzerlik yönlerine göre kategorileştirildiğinde 8 kategori elde edilmiştir. Bu kategoriler; ‘’Varlığı
Belli Olmayan Unsur Olarak Müdür’’, ‘’Üretkenlik Unsuru Olarak Müdür’’, ‘’Danışman-Yol Gösterici Liderlik Unsuru Olarak
Müdür’’, ‘’Değerli Unsur Olarak Müdür’’, ‘’Ciddiyet-Kural Unsuru Olarak Müdür’’, ‘’Koruyucu Unsur Olarak Müdür’’, ‘’Sorun
çözen ve gerekli ve Gerekli Unsur Olarak Müdür’’ ve ‘’Sertlik-Otorite Unsuru Olarak Müdür’’ şeklinde belirlenmiştir Çıkan
sonuçlara göre de yapılan çıkarımlar ve tartışmalar makale sonunda paylaşılmıştır.
Indigenous knowledge systems for land condition assessment and sustainable land management in the Talensi District, Ghana
Authors: Nasare Latif Iddrisu , Rahman Latifa Abdul , Darko Francis Diawuo
Published: January 2023

The quest for sustainable land management has led to the development of modern technologies for land condition assessment and management, but these approaches have often failed in rural contexts due to their high complexity and incompatibility with the socio-economic conditions of land users. Although indigenous systems are known to be accessible, compatible, and economically affordable for rural farmers, less is known about indigenous technologies for the assessment of the land condition and sustainable land management. The present study identified indigenous indicators for the assessment of land degradation and examined indigenous practices for sustainable land management in the Talensi district of the Upper East region of Ghana. The study employed a qualitative approach in which interviews were conducted with sixty farmers in three selected communities of the Talensi district. Generally, land degradation was observed by respondents in the form of soil degradation or loss of vegetative cover. Among indigenous indicators of land degradation, soil erosion emerged as the most frequent indicator (75%), while the proliferation of mining pits (10%) was the least observed indicator. Indigenous practices for sustainable land management in the district include stone bunding, contour ploughing and zero tillage. The most used soil fertility improvement practice identified was crop rotation (47%) while the application of compost/manure occurred as the least (18%) practice. The study recommends that the Ministry of Food and Agriculture incorporate indigenous knowledge and technologies into land management programmes.
Understanding The Sustainable Development Goals Concept: Malaysia Report and Trend
Authors: Nik Mahdi Nik Athirah , Fernando Yudi , Abdalla Yousif Abdelbagi
Published: January 2023

The desire to go even further in eradicating poverty in all aspects, dealing with climate change and eliminating inequalities has established the 2030 Agenda of Sustainable Development Goals (SDGs) in September 2915. The world leader adopted it at the historic UN summit. Malaysia has long sought to achieve the 2030 Agenda. The satisfaction degree of accomplishment of sustainable development the still low. Thus, this paper aims to shed light on the trend of sustainable development goals in Malaysia, which provides the community with information on a council's sustainable development goals. This has concluded Malaysia's three main SDG patterns, including reducing inequalities, climate action, and zero hunger. This study has concluded that the SDGs are crucial for achieving a better quality of life and sustainability. The SDGs' achievement does not solely depend on the government and its responsibility to all stakeholders. It is suggested that the better improvement of SDGs and better achievement, this study argue that government, industry, community and civil society organisations to work together to achieve shared and sustainable prosperity.
Prosopographical Method and Data of Central, Administrative, and Judicial Officers of the GDL in the Lithuanian Metric, 1528–1564
Authors: Vaitkus Tomas
Published: January 2023

In the digital age, databases are becoming a much more valuable recource for historians. From the abstract perspective, as an archive of the Grand Duchy of Lithuania, the Lithuanian Metrica has signs indicating that it is a massive database. Appropriate methods are needed to command such a large amount of information. A prosopography questionnaire lets us pick up data points from the Lithuanian Metrica, which is very useful for researching groups of persons from the governing body of the Grand Duchy of Lithuania. For example, with the help of a prosopographical questionnaire, we can extract specific data – personal, biographical, political career, social, economical – regarding officers who served under the Grand Duchy of Lithuania in the sixteenth century. LM’s judicial documents, privileges, and testaments are a great source of data for onomastics and reconstructions of marital statuses and social networks. Testaments also accurately indicate dates of death as well as the economical capital of the deceased. Military lists also give us a massive amount of information regarding the economical and political influence of a person. Unfortunately, the amount of type of sources are inconsistent, and a lot of persons from the researched group have “blind spots” on their prosopographical questionnaires. This reason can be partially resolved, as different types of sources in the LM can provide similar data, and thus make the prosopographical method a very useful tool for working with the LM.
Role of the Clergy of Vilnius St. John’s Church in the Life of the City’s Beggars in the 18th Century
Authors: Miškinytė Rūta
Published: January 2023

This paper examines an aspect of the functioning of the organization of Vilnius’ beggars that has not yet been sufficiently covered in the historiography: the role of the clergy of St. John’s Church in the life of the city’s beggars. This text focuses on the relationship between the clergy and the beggars during the 18th century. By using the personal documents of bishops, registers of the masses held in the church, and sources written by the beggars themselves or related to the aforementioned organization, it is shown that the clergy of Vilnius’ parish church not only took care of the spiritual needs of the beggars, but also looked after the finances of the organization and actively participated in its internal life, with their influence on the beggars manifesting itself in their personal relations with beggars beyond the scope of the organization.
Management of Hepatitis B and C during Pregnancy: Neonatal Implications
Authors: Pressman Katherine , Ros Stephanie
Published: January 2023

Over the last several decades, we have seen increased rates of infants born to persons with chronic hepatitis B virus (HBV) and hepatitis C virus (HCV). Due to this, many obstetric and pediatric organizations have updated their guidelines about screening and management of HBV and HCV during pregnancy, as well as the management of the exposed infant. Current guidelines suggest that all pregnant individuals should be screened for both HBV and HCV during each pregnancy. Appropriate medical care of pregnant persons and the newborn can significantly reduce the risk of vertical transmission.
The Role of Education Against Bullying Cases in Indonesia
Authors: Annisa Neng Nur , Aprilianto Dimas Sakti , Suhandani Maulana , Jayanti Maya Putri
Published: January 2023

The act of bullying is an attempt by an individual or group to suppress someone with the aim that the person being bullied feels hurt either mentally or physically and this is very dangerous, of course, because if the act of bullying has reached an extreme level, the result is that the victim being bullied can stress to commit suicide, and it's no secret that the school environment is one of the places where bullying often occurs. This study uses qualitative data collection techniques with a content approach. The data from the research results that we collected based on the Google form platform that we used, among others, obtained as many as 32 respondents in this bullying case study. In the results of our research we found various kinds of problems that respondents had experienced related to bullying starting from the form of bullying treatment in 4 forms namely Physical, Cyber, Mental and Verbal, then how did they respond to the bullying they had experienced to the role in the environment around the respondents in overcoming and overcome the problem of bullying.
Effects of Silica/Clay Nanoparticles on Microstructural and Mechanical Properties of Epoxy Based Adhesives
Authors: DİZECİ Şehram , KANDEMİR Ayse Cagil
Published: January 2023

Improving the mechanical properties of the epoxy-based adhesives with nanoparticles is one of the methods which justifies the use of adhesive joints significantly. This work studies the strength of adhesively bonded single-lap joints (SLJs) considering the pure adhesive, the reinforced adhesive with nano-silica particles (NSPs), nano-clay particles (NCPs), and a combination of both nano particles. Uniaxial tensile testing of the SLJs was conducted to reveal the failure loads of the joints and their elongations at failure. Furthermore, Scanning electron microscope (SEM) images and X-ray Diffraction (XRD) Analyses were used to investigate dispersion quality. It was observed that the use of just 1 wt.% NCPs or 2 wt.% NSPs improve the failure load significantly whereas the combination of both particles generally leads to large agglomerations. It is also concluded that the dispersion quality is a key to improve the strength by shifting the failure mechanism from adhesion to cohesion type.
Tėvų patirtys ruošiantis vaikui, turinčiam autizmo spektro sutrikimą, lankyti pradinę bendrojo ugdymo mokyklą
Authors: Raudeliūnaitė Rita , Gudžinskienė Vida
Published: January 2023

Straipsnyje pateikiami kokybinio tyrimo rezultatai, atskleidžiantys autizmo spektro sutrikimą (toliau ASS) turinčių vaikų tėvų patirtis rengiantis vaikui pradėti lankyti pradinę bendrojo ugdymo mokyklą. Tyrime išryškėjo keturi svarbūs ASS turinčių vaikų rengimosi mokyklai aspektai: mokyklos pasirinkimo dilemos ir kriterijai, bendradarbiaujančio santykio su mokykla užmezgimas prieš pradedant vaikui lankyti mokyklą bei vaiko pasirengimas mokyklai.
Cálculo de la velocidad de desgaste abrasivo en engranajes de dientes rectos y helicoidales con perfil evolvente, utilizando una GUI de Matlab
Authors: Mena Chavarrea José Miguel , Antonio Granizo José , Hernández Dávila Eduardo Segundo , Audelo Guevara Mario Efraín
Published: January 2023

La presente investigación se originó con el objetivo de diseñar un \emph{software} con Matlab que permita calcular la velocidad de desgaste abrasivo de engranajes rectos y helicoidales de perfil evolvente. Donde, las generalidades no estudiadas sobre el diseño de engranajes han generado consecuencias negativas en la funcionalidad y fallas catastróficas que han producido paras improvistas de procesos mecánicos, por lo cual entender las causas de los mismos se vuelve fundamental. El cálculo del desgaste abrasivo de los pares tribológicos en maquinaria pesada dependerá del grado de trituración o tamaño de las partículas abrasivas, la dureza, el material del engrane base, el régimen de lubricación y las condiciones geométricas que determinen la naturaleza del contacto tribológico, así como el tiempo y velocidad de uso de la maquinaria pesada. Inicialmente, se establece el entorno teórico que compone el estudio basado en los principales componentes como engranajes, lubricación, el acero, los tratamientos térmicos y, al final, Matlab.
Seguidamente, se establecieron los modelos matemáticos de Archard y Kraglesky que fueron adaptadas a las circunstancias del problema y en función de esta información formular un software capaz de calcular la velocidad de desgaste abrasivo mediante una herramienta gráfica de usuario de Matlab. Se procede a ejecutar el cálculo manual con las variables determinadas, tomando datos experimentales obtenidos de investigaciones previas y que cumplan con las variables determinadas para la ejecución del proceso matemático, dado que los resultados generados a través del software puedan ser tabulados, graficados en Excel y comprobados con el desarrollo matemático manual. Buscando la comparación, diferenciación y tendencia del comportamiento de la velocidad de desgaste, variando los parámetros involucrados en el proceso utilizando los dos modelos matemáticos planteados.
Rendimiento para la interoperabilidad entre Rasperry pi, ESP8266 y PLC con Node-RED para el IIoT
Authors: Torres Ventura J. , Ruelas Puente A. H. , Herrera García J. R.
Published: January 2023

Este trabajo evalúa la viabilidad de integrar en una red descentralizada las placas de bajo costo Raspberry pi, microcontroladores ESP8266 con equipos industriales de Controladores Lógicos Programables (PLC). Estos dispositivos serán los nodos que participan en el intercambio de datos entre el piso de manufactura y los servicios empresariales de manera simple, fiable y económica. Los nodos de la red producen y consumen datos que son intercambiados por un nodo gestor de protocolos open source llamado Node-RED. El gestor de protocolos es un servidor con núcleo de Linux sobre un microprocesador RISC (Reduced instruction set computing). Los sensores en los nodos de manufactura utilizan microcontroladores SoC (System On Chip) y mediante el concepto de Edge computing adquieren, procesan y envían sus datos al gestor de protocolos. Así, mediante la herramienta Iperf3, Wireshark y MTR, mediremos el rendimiento del enlace de comunicaciones y el estado que guardan los nodos participantes en sus procesos producción/consumo de datos.
Sentimental analysis of COVID-19 twitter data using deep learning and machine learning models
Authors: Darad Simran , Krishnan Sridhar
Published: January 2023

The novel coronavirus disease (COVID-19) is an ongoing pandemic with large global attention. However, spreading fake news on social media sites like Twitter is creating unnecessary anxiety and panic among people towards this disease. In this paper, we applied machine learning (ML) techniques to predict the sentiment of the people using social media such as Twitter during the COVID-19 peak in April 2021. The data contains tweets collected on the dates between 16 April 2021 and 26 April 2021 where the text of the tweets has been labelled by training the models with an already labelled dataset of corona virus tweets as positive, negative, and neutral. Sentiment analysis was conducted by a deep learning model known as Bidirectional Encoder Representations from Transformers (BERT) and various ML models for text analysis and performance which were then compared among each other. ML models used were Naïve Bayes, Logistic Regression, Random Forest, Support Vector Machines, Stochastic Gradient Descent and Extreme Gradient Boosting. Accuracy for every sentiment was separately calculated. The classification accuracies of all the ML models produced were 66.4%, 77.7%, 74.5%, 74.7%, 78.6%, and 75.5\%, respectively and BERT model produced 84.2%. Each sentiment-classified model has accuracy around or above 75%, which is a quite significant value in text mining algorithms. We could infer that most people tweeting are taking positive and neutral approaches.
Glotopolítica de la lengua occitana en diacronía: tres actos y una incógnita
Authors: Boyer Henri
Published: January 2023

La historia del occitano, de sus usos, sus representaciones y sus estatutos glotopolíticos, no puede reducirse simplemente al relato de un largo proceso de sustitución. Bien es cierto que la normalización no pudo llevarse a cabo, a pesar de una resiliencia incontestable, pero sin embargo la muerte de esta lengua, anunciada desde hace mucho tiempo, sigue sin producirse: daremos una prueba de ello en esta intervención.

Los diferentes Actos de esta muerte anunciada se terminan con una incógnita: ¿qué revela el síntoma del retorno de la lealtad de ciertos occitanos en el siglo XXI? Los resultados de una encuesta sociolingüística reciente nos permitirán dar elementos de respuesta a esta interrogación.
Lengua vernácula y dimensión pedagógica en la teología mística: una nota breve
Authors: Lázaro Pulido Manuel
Published: January 2023

La teología mística se desenvuelve en una teología interior y desarrollará toda una labor pedagógico-pastoral dentro de su metodología de acercamiento a Dios. Frente al escolasticismo y la teología dogmática explicada en latín en las cátedras universitarias para formar a teólogos y pastores, el ideal místico tiene conciencia de constituirse en un itinerario espiritual para la formación interior de los religiosos y del pueblo con el que conviven, tal como señala “Juan de la Cruz, O.P., en 1555: “En nuestra edad y en nuestras tierras el Señor despierta muchos hombres y mujeres… Y los esfuerza para vida y ocupaciones espirituales”. Este deseo universal en el que cada uno de los que inician el camino místico sigue su propio recorrido desde la Edad Media exigirá un cambio metodológico en el que se incluye el uso de la lengua vernácula, en este caso el español, en un contexto de humanismo castellano y de una Reforma en ciernes.
The first living newborn case with 7706G˃A missense mutation: Alpers-Huttenlocher syndrome
Authors: ÖZDEMİR Mustafa , HAMİTOĞLU Şerif , ÖZLÜ Ferda , YAPICIOĞLU Hacer , GÜL MERT Gülen , SATAR Mehmet
Published: January 2023

Alpers-Huttenlocher syndrome (AHS) is an uncommon autosomal recessive mitochondrial DNA depletion disease. The classic clinical triad of progressive developmental regression, liver degeneration, and seizures helps define the disorder, but a wide range of clinical expressions occur. The most common mutations in childhood have been identified in the cytochrome c oxidase Ⅰ and Ⅳ genes. The 7706G˃A missense mutation in the Cox Ⅱ gene was previously reported in one case after postmortem histological study. Consequently, our patient is the first patient diagnosed with AHS with a 7706G˃A missense mutation in the Cox Ⅱ gene while alive. We proposed that 7706G˃A missense mutation is rare and should be more lethal than other mutations that cause Alpers-Huttenlocher syndrome.
Highlighting steroid indications for Kikuchi Fujimoto disease: a case report
Authors: GRANİT SEMAVİ Deniz , ULAŞ Turgay
Published: January 2023

Kikuchi Fujimoto disease (KFD) is a rare, generally benign and self limited condition with an unknown etiology. There isn’t a guideline for treatment of KFD, recommendations for treatment are based on clinical experience and management is typically supportive. However, sometimes more ominous course of the disease may be experienced. Thus, for the patients with severe disease, refractory symptoms and recurrences, more definite and efficient treatment options are required. Here, we aimed to emphasize the indications of steroid treatment via a case of KFD resolved after systemic steroids.
The Prediction of Quality of Life - based on Personality Traits and Spiritual Intelligence in the Elderly
Authors: Farmani Fardin , Gholami Sehchek Shabnam , Sarmadi Maryam , Jahanshahloo Morteza
Published: January 2023

Introduction: Considering the increasing trend of the elderly population in Iran, attention paid to this critical phase, both socially and psychologically, is essential in improving their quality of life. The present study aimed to investigate prediction of quality of life - based on personality traits and spiritual intelligence in the elderly.
 
Methods: This correlational study  carried out on older adults in Tehran who lived in nursing homes in 2020 and 182 of them were selected by convenience sampling. The NEO Personality Inventory (NEO-PI), The Spiritual Intelligence Self-Report Inventory (SISRI-24) and Leiden-Padua Questionnaire (LEIPAD questionnaire) were used for data collection. Descriptive statistics (mean, standard deviation) and inferential statistics (correlation and stepwise regression analysis) were used for data analysis. The correlation matrix and stepwise regression were used to predict the quality of life scores based on personality and spiritual intelligence.
 
Results: There was a significant relationship between personality traits with spiritual intelligence and quality of life (r: 0.361, p < 0.05). Also, there was a significant relationship between spiritual intelligence and quality of life (p < 0.05). Personality traits of neuroticism, extraversion, and spiritual intelligence could predict a total of 38.5% of the variance in quality of life (p < 0.05).
 
Conclusion: The quality of life has a significant relationship with both spiritual intelligence and personality traits, so, spiritual intelligence and personality components can predict the quality of life in the elderly.
Critical Organ Dose Estimation from Tc-99m-MIBI in Nuclear Medicine Cardiology Based on Distribution Data in Rats
Authors: Fallah Mohammadi Gholamreza , Khorrami Moghadam Alireza , Abaszadeh Fariba , Mahdavi Mohammad
Published: January 2023

Purpose: Calculating the organs' radiation dosage in cardiac nuclear medicine procedures is essential in order to identify critical organs, radiation risk assessment and optimization dose value in the injection of radiopharmaceutical drugs. In this study, the biological distribution of 99mTc-2-Methoxyisobutylisonitrile) 99mTc-MIBI as the most common radiopharmaceutical in a cardiac study in human organs based on animal samples was investigated.
Materials and Methods: After 99mTc-MIBI preparation, radiopharmaceutical was injected into 15 rats. After sacrificing rats, the uptake of radiopharmaceuticals in critical organs at 15, 30, and 45 minutes was measured using an High Purity Germanium (HPGE) detector and the percentage of injected dose per gram of organs was calculated. The cumulative activity was calculated from the radiopharmaceutical transformation diagram with time. The absorption of a radioactive complex in human organs based on animal data was calculated by applying a correction factor. The organs dose was calculated using S factor and the effective dose was calculated using tissue weighting factors.
Results: The mean effective dose per unit of activity was 0.0062 mSv/MBq. The mean effective dose of 27.5 mCi radiopharmaceutical injection was 6.3 mSv. In this study, the absorbed dose in blood, heart, lung, thyroid, liver, spleen, stomach wall, muscle, and bone was calculated as 0.28, 2.92, 1.85, 24.82, 11.13, 7.03, 20.95, 1.11, 4.97, and 22.22 mGy, respectively.
Conclusion: The effective dose of human organs based on the animal model in the study of cardiac nuclear medicine was evaluated by injection of 99mTc-MIBI radiopharmaceutical. The kidneys, salivary glands, thyroid, and spleen were the most critical organs that should be considered in dose optimization studies. The effective dose limit was 28% lower than the values reported in international references.
Biological Features of CD5+ CD19+ B1 Cell and Natural IgM (VH4-34) in Chronic Lymphocytic Leukemia vs. Multiple Sclerosis
Authors: Pezeshki Shaghayegh , Jazayeri Mir Hadi , Chahardouli Bahram , Tajik Nader , Nabavi Seyed Massood , Akbarzadeh Mahdi
Published: January 2023

Chronic lymphocytic leukemia (CLL) is the clonal expansion of mature CD5+ B cells and the most common lymphoproliferative disease in adults (B1-CLL). B1 cells' anti-inflammatory effects include the production of natural IgM (nIgM) by the spleen and bone marrow, decreased inflammatory cytokines as a primary response to maintaining tissue homeostasis, and enhanced release of transforming growth factor β (TGFβ).
We used the flow cytometry technique in peripheral blood from patients with CLL and multiple sclerosis (MS) to immunophenotype B cells and their subpopulations. Whole blood from CLL and MS patients, as well as healthy controls, was used to detect nIgM using the VH4-34 gene copy number and real-time RT-PCR.
We found that the proportion of CD5+ B cells was significantly lower in MS patients than in the control group and that CD5+ B lymphocytes were significantly higher in CLL patients than in the control group. Compared to the control group, CLL patients had significantly higher levels of the VH4-34 gene copy number. On the contrary, MS patients had significantly lower VH4-34 gene copy number levels compared to the control group.
As the number of antibodies in CLL patients increases due to the high number of B1 cells, we propose a new way to treat MS by extracting this natural antibody from the sera of CLL patients and injecting it into MS patients.
Honouring Water: The Mistawasis Nêhiyawak Water Governance Framework
Authors: Mora Maria , Johnston Anthony , Watson Michelle , Bharadwaj Lalita
Published: January 2023

Collaborative water governance in Indigenous territories requires the building of a nation-to-nation relationship where different water worldviews and knowledges are acknowledged, valued, and included in water governance. This article presents the Mistawasis Nêhiyawak Honour the Water Governance Framework, an alternative collaborative water governance approach in Saskatchewan, Canada. The Nêhiyawak principles, identity, knowledge, and self-determination are its foundation. Equitable dialogue is the central axis. The framework represents an alternative water governance structure to the current Canadian system that may more effectively respond to the water challenges of this First Nation. This framework supports the appeal from Mistawasis First Nation and other Nations, for the de-construction of hegemonic colonial water governance systems towards the co-construction of shared processes of water participation, decision-making, and responsibility.
Proposing a New Managerial Model for Digital Transformation
Authors: Tayazime Jihane , Moutahaddib Aziz
Published: January 2023

Digital transformation is a gateway to innovation and new models of organization, operations, and business models. The quick response of managers and leaders is becoming the key to successful digital transformation, followed by strategic flexibility according to data testing results. These results highlight the importance of agile leadership in today’s changing organizational environment (Fachrunnisa et al., (2020). Hence why it is imperative to take into consideration all employees’ perceptions of management to avoid resistance to change. Thus, in this research paper, we analyze the current managerial environment to better guide digital transformation through a survey destined for both managers and employees, assessing the current situation of organizational management from a diversity of perspectives. We then propose a new digital transformation managerial model based on significant correlations between the models’ variables using the Chi-squared test.
The Comparison Between the Hungarian and Romanian National Security Strategies
Authors: Veress Csongor Balazs
Published: January 2023

In 2020 first Hungary, later Romania, two member states of NATO, EU and PESCO adopted their own Nation Security Strategies. There was a need in both mentioned countries for new defense strategies because in recent years new challenges and threats have emerged, like the annexation of Crimea, the destabilization of Ukraine, and the migration crisis. These documents describe the two countries’ place in the international system, list the threats and challenges to their security, and finally try to give a solution based on their possibilities and capabilities. The strategies also carry a message to neighbors, allies, and future rivals. The document's aim is the protection of core national values. In this paper, my goal is to offer an overview of the strategic documents and to analyze first the Romanian National Defense Strategy. The Hungarian National Security Strategy, and finally to highlight the similarities and find the differences like national sovereignty, protection of Christian values, or the importance of a European army. In both security documents old and new threats appear like terrorism, climate change, migrant problems, hybrid warfare, arms, and drug trafficking. Each strategy is an official communication tool, an official policy message to external and internal actors at different levels and of different types that influence national security. To achieve my goal, I used the methods of document analysis and content analysis on the primary sources. The purpose of the research is to compare two neighboring countries' strategies, and how they react to their national threats.
Interaction between Food and Anticoagulants in Patients with Cardiovascular Diseases
Authors: Prifti Rudina , Kreka Manika
Published: January 2023

Cardiovascular diseases are one of the most common diseases in the world. Anticoagulants and other drugs are prescribed as a treatment for these diseases. However, polypharmacy may increase the risk of drug-drug or food-drug interactions and decrease patient compliance. Food-drug interactions may put the patient at risk for serious adverse effects and reduce the safety and efficacy of treatment. Food‐drug interaction is a common problem that has occurred as a result of the concomitant use of multiple drugs with food. Food-drug interaction is the term used to describe how food affects a medication in the body. Food can alter the effectiveness of the medication, make unwanted side effects better or worse, or even bring on brand-new negative effects. Drugs may alter how the body processes food. Consumption of foods that contain vitamin K makes anticoagulant therapy less effective. On the other hand, patients should be careful when consuming foods like garlic, ginseng, ginger, and ginkgo to avoid the undesirable effect of hemorrhage. Among the medical records examined, no advice or recommendations were provided regarding anticoagulant-food interactions, no details about the time of taking anticoagulant drugs and the exact time of eating meals were given and there were few instances in which medicine dosage was altered due to a food association.  A majority of patients who completed an anonymous survey in community pharmacies were not informed about food-drug interactions. Healthcare professionals should advise patients taking anticoagulants to be careful with the food they consume and clinicians should manage the time and dose variability of the medicine so a successful therapy can be achieved.
Étude des Réservoirs Gréseux des Zones Sud et Sud-Est de la Marge d’Abidjan (Côte d’Ivoire)
Authors: Jonas Ablé Guiako , Issac Féa , N’Goran Yao , Kader Bamba Moritié , Mamery Doukouré
Published: January 2023

Les réservoirs gréseux des puits Yans 1, 2, 3, 4, 5, 6 et 7 du bassin offshore de Cote d’Ivoire ont fait l’objet d’analyse à l’aide du granulomètre, du diffractomètre de rayon X et du spectromètre de fluorescence à rayon X. Les réservoirs gréseux des puits Yans 1 et 2 d’âge Albien et des puits Yans 3, 4 et 5 d’âge Campanien-Cénomanien sont constitués de sables moyens à grossiers et médiocrement triés, tandis que ceux des puits Yans 6 et 7 d’âge Turonien-Cénomanien sont silteux et bien trié. La minéralogie et la composition chimique des grès réservoirs des puits Yans 1, 2, 6 et 7 montrent qu’ils sont moins matures que ceux des puits Yans 3, 4 et 5. La dissolution des feldspaths et la formation du quartz et de la kaolinite secondaires impactent sur la qualité des réservoirs. Ainsi, la qualité des réservoirs gréseux des puits Yans 3, 4 et 5 est meilleure que celle des puits Yans 1, 2, 6 et 7. Les minéraux lourds sont plus abondants dans les sables grossiers et moyens que dans les sables fins. Seul, le zircon est fréquent dans les réservoirs silteux. Les rapports des éléments chimiques Al2O3/TiO2 et Zr2O3/Y indiquent que tous les sédiments détritiques meubles (sables et siltites) qui constituent les réservoirs gréseux de tous les puits Yans prennent leur source du démantèlement du socle birimien. La chloritisation et l’illitisation sont les processus qui ont été à la base de la transformation des smectites en minéraux simples et interstratifiés.

 

The sandstone reservoirs of Yans 1, 2, 3, 4, 5, 6 and 7 drillings in the offshore basin of Ivory Coast were analyzed using the particle sizer analyzer, X-ray diffractometer and X-ray fluorescence spectrometer. The sandstone reservoirs of Yans drillings 1 and 2 of Albian age and Yans drillings 3, 4 and 5 of Campanian-Cenomanian age are constituted of medium to coarse and poorly sorted sands, While those of Yans drillings 6 and 7 of Turonian-Cenomanian age are silty and well sorted. The mineralogy and chemical composition of the reservoir sandstones from Yans 1, 2, 6 and 7 drillings show that they are less mature than those from Yans 3, 4 and 5 drillings. The dissolution of feldspars and the formation of secondary quartz and kaolinite have an impact on the quality of reservoirs. Thus, the quality of the sandstone reservoirs of Yans 3, 4 and 5 drillings is better than that of Yans 1, 2, 6 and 7 drillings. Heavy minerals are more abundant in coarse and medium sands than in fine sands. Alone, zircon is common in silty reservoirs. The ratios of the chemical elements Al2O3/TiO2 and Zr2O3/Y indicate that all the loose detrital sediments (sands and siltstones) which constitute the sandstone reservoirs of all the Yans drillings originate from the dismantling of the Birimian bedrock. Chloritization and illitization are the processes that have been at the basis of the transformation of smectites into simple and interstratified minerals.
Tingkat Pemahaman Moderasi Beragama Mahasiswa di Perguruan Tinggi Umum dan Perguruan Tinggi Keagamaan Islam Negeri
Authors: Selvia Sasmi , Rahmat Munawar , Anwar Saepul
Published: January 2023

Penelitian ini bertujuan untuk membandingkan tingkat pemahaman tentang moderasi beragama mahasiswa di perguruan tinggi umum dan keagamaan. Penelitian ini menggunakan pendekatan kuantitataif dengan desain komparatif. Dengan menggunakan teknik sample random sampling, terpilih sampel sebanyak 160 orang dengan rincian 80 sampel dari mahasiswa Perguruan Tinggi Umum (PTU), dan 80 orang dari mahasiswa Perguruan Tinggi Keagamaan Islam Negeri (PTKIN). Hasil penelitian menunjukkan bahwa rata-rata skor tingkat pemahaman mahasiswa PAI di PTU sebesar 131,76 atau berada pada kategori sedang. Sedangkan, rata-rata skor tingkat pemahaman mahasiswa PAI di PTKIN sebesar 128,01 yang juga berada pada kategori sedang.  Kemudian hasil tersebut dianalisis dengan menggunakan Uji Mann Whitney U. Berdasarkan hasil uji tersebut, diperoleh hasil asymp. Sig. (2-tailed) sebesar 0,006 yang lebih kecil dari 0,025. Maka, dapat disimpulkan bahwa terdapat perbedaan rata-rata yang cukup signifikan antara tingkat pemahaman mahasiswa PAI di PTU dan PTKIN terhadap konsep moderasi beragama. Dimana, rata-rata pemahaman mahasiswa PAI di PTU lebih besar 3,69 poin daripada pemahaman mahasiswa PAI di PTKIN. Namun pemahaman mahasiswa PAI terhadap moderasi beragama baik di PTU maupun PTKIN berada pada kategori sedang. Artinya pemhaman mereka terhadap moderasi beragama cukup moderat.