bluuebunny/crossref_metadata_2025 huggingface dataset:
Atherogenicity of blood plasma lipid spectrum during sugar-reducing therapy in patients with noninsulin-dependent diabetes mellitus
Authors: Ametov A. S. , Perova N. V. , Vinnitskaya N. L. , Topchiashvili V. Z.
Published: October 2019

Blood plasma lipoprotein spectrum and phospholipid spectrum of high density lipoproteins (HDLP) was studied in patients with newly detected noninsulin-dependent diabetes mellitus (NIDDM) and in patients with "secondary failure" of sulfanilamide drugs. Hyperlipidemia, mainly at the expense of increased concentration of triglycerides, very low density lipoproteins, total cholesterol, and low density lipoprotein cholesterol, was detected in the patients. HDLP phospholipid composition was disturbed, with sphyngomyelin level increased and lecithin content decreased. Glurenorm therapy led to reduction of the atherogenicity of blood plasma lipid spectrum despite the persistent basal and postload hyperinsulinemia, thus indirectly indicating an improved function of endogenous insulin. Antiatherogenic effect of glurenorm is evidently mediated by reduction of insulin resistance due to extrapancreatic effect of the drug. Intensive insulin therapy of patients with secondary failure led to a marked reduction of atherogenic components of lipid spectrum. The hypolipidemic effect of insulin therapy seems to be due to recovery of the inhibitory effect of insulin on lipolysis against the background of improved sensitivity to insulin and reduced insulin resistance. A positive effect of insulin therapy on lipid metabolism should not be regarded as an evidence in favor of theoretical assumptions and apprehensions about increased risk of atherogenesis as a result of exogenous hyperinsulinemia.
Hyperhomocysteinemia: a risk factor for vascular complications of diabetes
Authors: Bondar' I. A. , Klimontov V. V.
Published: October 2019

Vascular complications are a leading cause of reduced quality and longer life of patients with diabetes mellitus (DM). The mechanisms of development of these complications are not fully disclosed. It is known that in not all cases the occurrence and progression of diabetic angiopathies can be explained by traditional risk factors, such as hyperglycemia, arterial hypertension, smoking or dyslipidemia. Therefore, the search for the missing links in the pathogenesis of angiopathy remains an extremely urgent task.
Paraoxonase activity and lipid peroxidation in female patients with type 2 diabetes mellitus and without coronary heart disease
Authors: Gorshunskaya. M. Yu.
Published: October 2019

The rate of lipid peroxidation and the parameters of antioxida- tive defense, including the activity of paraoxonase that is essen­tial for the prevention of low-density lipoprotein oxidation, was studied in 229female patients with type 2 diabetes mellitus with and without coronary heart disease (CHD) under varying glyc­emic control. Carbohydrate and lipid metabolisms were explored by unified biochemical studies, blood insulin levels were meas­ured by radioimmunological assay. The activity of paraoxonase associated with high-density lipoproteins of ester hydrolase was spectrophotometrically determined by using paraoxan as a sub­strate. Along with dyslipoproteinemia and insulin resistance, there was a drastically reduced paraoxonase activity that was as­sociated with the high-density lipoproteins of the antioxidant en­zyme and more pronounced in diabetics with CHD. A highly sig­nificant inverse correlation of the activity of the enzyme with the rate of lipid peroxidation and a less close relationship to basal glycemia have been verified, which substantiates the polygenic nature of decreased paraoxonase activity in diabetes mellitus.
A fragment of apolipoprotein B with insulin-like immunoreactivity
Authors: Panin L. Ye , Poteryaeva O. N. , Voronova O. S. , Shevkoptyas O. P. , Polyakov L. M.
Published: October 2019

The purpose of this study was immunochemical analysis of a fragment of apolipoprotein В with insulin-like immunoreactivity. We denoted it as peptide B. The peptide isolated by electrophoretic elution was used to obtain specific antibodies. Antibodies to peptide В reacted with apolipoprotein B-100, whole serum, serum after precipitation of β-lipoproteins, and with supernatant after removal of all lipoproteins by ultracentrifugation. Enzyme immunoassay was optimized for evaluation of serum peptide В after precipitation of β-lipoproteins. Serum concentrations of peptide В were increased in patients with type 2 diabetes mellitus in comparison with donors. The content of peptide В increased with increase of body weight index and disease duration.
Digitopalmar dermatoglyphics in patients with diffuse toxic goiter
Authors: Kalinin A. P. , Sidorova О. P. , Kamynina T. S. , Tsyplakova G. Yu. , Golubeva L. B.
Published: October 2019

Dermatoglyphic parameters were studied in 86 patients with diffuse toxic goiter (66 women and 20 men). Palmar impressions were obtained with printing ink by contact method on paper. The position of the axial palmar triradius, skin pattern on the fingers and palm surfaces were assessed, digital and palmar crest count was analyzed. A statistically reliable distal dislocation of the axial palmar triradius and low incidence of patterns on the thenar were detected. Dermatoglyphic parameters characteristic of diffuse toxic goiter indicate that it is a genetically determined disease and may be used in medicogenetic counselling.
Hormonal analysis in the diagnosis of thyroid diseases: A lecture
Authors: Goncharov N. P.
Published: October 2019

The creation of methods of radioimmunological analysis (RIA) to determine hormones had a decisive influence on the development of modern endocrinology and especially thyroidology. Since 1973, RIA methods have become routine diagnostic methods for the determination of thyroxine (T4), triiodothyronine (T3) and thyroid stimulating hormone (TSH). However, for a long time they made it possible to determine only the fractions of hormones associated with transport proteins, and RIA methods for determining TSH did not allow to determine its low (< 0.1 Mme/l) concentrations. Later, variants of RIA were developed based on the immunometric principle, using solid-phase carriers and monoclonal antibodies. This made it possible to determine, along with the general T4 and T3, also their free forms. Namely free T4 and T3 (FT4 and FT3) provide the entire spectrum of biological activity. Their definition is the most informative in assessing the functional state of the hypothalamus-pituitary-thyroid gland. The IRMA principle allowed to increase the sensitivity of the method for determining TSH to 0.16 mIU/L. This level of sensitivity satisfied clinicians in assessing the euthyroid state and hypothyroidism, but it did not allow to differentiate the normal level of TSH from subnormal in patients with thyrotoxicosis. In the last decade, fundamentally new non-isotopic technologies of hormonal immunoassay have been created. The sensitivity of this method in determining TSH was brought to 0.03 mIU/L. Currently, the determination of FT4 and TSH using the hypersensitive method is a strategic diagnostic approach to assessing the hormonal status of the thyroid gland.
Involvement of progesterone in thermoregulation disorders in rats treated with complete Freund's adjuvant
Authors: Gurin V. N. , Semenenya I. N.
Published: October 2019

Changes in blood serum progesterone, thyrotropic and thyroid hormone levels in white outbred rats during development of a subfebrile state induced by a single injection of complete Freund's adjuvant containing killed and dried Mycobacteria butyricum were studied. A rise of body temperature in males and females was associated with an increased level of progesterone and a decreased content of thyrotropic and thyroid hormones in the blood. After normalization of body temperature (4 days after drug injection), the content of progesterone did not differ from the baseline level. Hyperthermia arrest by indomethacin failed to appreciably influence the blood level of this hormone.
Laser therapy of diabetics with dyslipemia
Authors: Kovaleva T. V.
Published: October 2019

This paper sums up the results of 3-year observation of 59 patients with diabetes mellitus in an outpatient setting. 37 of these patients received combined laser therapy and 22 were controls. A significant prolonged clinical effect was observed in the patients treated by combined laser therapy. These results can be useful in follow-up of diabetics in an outpatient setting.
Magnetic resonance imaging in the diagnosis of hypothalamopituitary diseases in patients with true premature sexual development
Authors: Vorontsov A. V. , Semicheva T. V. , Peterkova V. A.
Published: October 2019

То evaluate the incidence of different types of organic abnormal­ities occurring in premature sexual development (PSD) of central genesis and to study a role of magnetic resonance imaging (MRI) in the diagnosis of PSD, MRI was used in 33 patients with a clin­ically established diagnosis of true (gonadotropin-dependent) PSD of central genesis. Among the examined children with PSD, hypothalamic hamartoma was detected in 27.3%) of the patients; there were no MRI data suggesting hypothalamopituitary abnor­malities in 72.7%o. On the MRI images, a hypothalamic hamar­toma appeared as a round or oval mass having a well -defined outlines, a homogeneous structure, 3 to 15 mm in size, which is located in the projection of mamillary bodies or retrochiasmally. Patients with PSD were found to have an increased volume of the adenohypophysis mainly due to the vertical size as compared with a group of healthy children of the same age.
Enfoque Histórico-Cultural como estrategia en la formación de Pedagogos en una Universidad Privada de San Luis Potosí, México
Authors: Tovar Mónica Guadalupe Hernández , Loredo Montserrat Cañedo
Published: October 2019

En el siguiente artículo se presenta una pesquisa teórica que sustenta el aprendizaje social basado en el Enfoque Histórico-Cultural, iniciado por Vygotsky, con la cual trabaja desde una Didáctica Desarrolladora con los estudiantes de la Licenciatura en Pedagogía en la Universidad Tangamanga, Campus Tequis en San Luis Potosí, México. Estas ideas brindan al docente la posibilidad de generar, desde el aula donde trabaja, las situaciones precisas que fomenten el aprendizaje colaborativo a través de una orientación activo-transformadora para la adquisición del conocimiento y los aprendizajes reales en los estudiantes.
Por uma Didática Desenvolvimental da subjetividade no ensino de Música na escola
Authors: Farias Lucielle Arantes
Published: October 2019

Este texto trata-se de um resumo da tese "Por uma Didática Desenvolvimental da subjetividade no ensino de Música na escola". Situada no campo da Didática, a pesquisa de Doutorado teve a Didática Desenvolvimental da Subjetividade no ensino de Música como seu objeto, assumindo como objetivo geral "implementar uma proposta didática ao ensino de Música na escola favorecedora do desenvolvimento integral de estudantes considerados em seu potencial ativo e gerador de realidades subjetivas", e, como objetivos específicos, definir princípios de uma Didática Desenvolvimental aportada na Teoria da Subjetividade; construir um olhar sobre expressões de sentidos subjetivos envolvidos em processos de ensino-aprendizagem musicais de estudantes do ensino fundamental e desenvolver estratégias didáticas para aulas de Música comprometidas com a produção de sentidos subjetivos.
Educação musical na perspectiva histórico-cultural: uma didática para o desenvolvimento da musicalidade
Authors: Pederiva Patrícia Lima Martins , Gonçalves Augusto Charan Alves Barbosa
Published: October 2019

O presente texto busca compartilhar reflexões e práticas pedagógicas em educação musical alicerçadas na Psicologia Histórico-Cultural de Lev Semionovich Vigotski. Nele apresentamos formulações de processos didático-pedagógicos específicos em música orientados para o desenvolvimento da musicalidade, relativos à atividade musical e ao conhecimento nessa atividade educativa que se fundamentam nos pressupostos epistemológicos da Teoria Histórico-Cultural. Busca-se desta maneira, contribuir com as discussões existentes no âmbito acadêmico e com o compartilhamento de conhecimentos constituídos até aqui e caminhar para uma didática específica em educação musical de base histórico-cultural.
La Didáctica en la Investigación Administrativa en la Educación Superior, desde un Enfoque Sociocultural
Authors: Sánchez-Macías Armando , Toruncha José Zilberstein , Pugliese Virginia Azuara
Published: October 2019

Ante una nueva realidad basada en avances tecnológicos, globalización y cambios en la sociedad del conocimiento, la Pedagogía y la Didáctica deben transformarse. El objetivo de este artículo es presentar la caracterización de principios y prácticas del Modelo Pedagógico y la Concepción Didáctica en la Investigación Administrativa, a través de la revisión teórica contextualizada. Planteando lineamientos en el proceso enseÃ±anza-aprendizaje, proponiendo al Diagnóstico Organizacional y las propuestas basadas en la Administración Estratégica, como los ejes didácticos en la Investigación Administrativa. Las Instituciones de Educación Superior, deben asumir el compromiso y la responsabilidad de convertirse en formadores de recursos humanos comprometidos con la sociedad, formando profesionales competentes a través de una educación retomando la perspectiva Sociocultural.
Formação de professores:
Authors: Torres Mônica Moreira de Oliveira
Published: October 2019

O texto aborda a formação de professores, as políticas curriculares e reflexos nas licenciaturas. A partir das Diretrizes Curriculares de Formação de Professores vigentes, reflete sobre projetos pedagógicos de curso para formação profissional do professor, as possibilidades de estruturas curriculares mais híbridas de formação em articulação com espaços profissionais. Objetiva identificar contribuições das Diretrizes para formação profissional do professor. Nesse sentido, identifica dispositivos que favorecem a essa formação. Dentre eles destacamos: dimensão pedagógica, práticas de ensino, estágio; iniciação à docência; articulação com as escolas e professores regentes na formação, dentre outros.
Inventory of poisonings and toxicological studies carried out on Atractylis gummifera L.: A review
Authors: Bouabid Khadija , Lamchouri Fatima , Hamid Toufik , Faouzi My El Abbes
Published: October 2019

Atractylis gummifera L. belongs to the family Asteraceae is widely used in traditional Moroccan medicine for its therapeutic effects (diuretic, purgative, emetic, abortive), but it causes serious and fatal poisonings, hence the objective of this work is to describe the current state of intoxication caused by A. gummifera in the Mediterranean and to summarize the toxicological studies carried out on this plant. The working methodology we adopted consisted in collecting data published in Arabic, French and English in specialized articles, books and on websites. Research results showed that the Centre Anti Poison and Pharmacovigilance of Morocco declared A. gummifera was in second place in the occurrence of poisonings in between January 1980 and December 2008. The synthesis of experimental work on plant toxicology showed that the lethal dose of A. gummifera varies according to the animal model used (rat or mouse), the route of administration (intraperitoneal, oral or intravenous) and the part of the plant used. The root has been found to be the most toxic part of the plant. The toxicity of A. gummifera is due to atractyloside and gummiferine, which are inhibitors of oxidative phosphorylation that prevent the formation of ATP from ADP in intracellular organelles. This study shows the interest in raising public awareness of the toxicity of A. gummifera and in rationalizing its use in traditional medicine.
Arsenic stress on photosynthesis and growth in Ipomoea aquatica
Authors: Joardar Jagadish Chandra , Afrin Nishad , Halder Milton
Published: October 2019

An experiment was conducted to understand the effect of arsenic (As) on photosynthetic pigments in Ipomoea aquatica leaves, its growth performance and As uptake in edible plant parts. The experiment was designed with three levels of As treatments, viz. 10, 20, and 40 mg As kg-1 soil along with control, and three biological replications. I. aquatica was grown for six weeks after seed germination. Chlorophyll-a, chlorophyll-b, carotenoid, plant height and weight increased at lower rate of As application (10 mg kg-1) in soil. Higher As (20 and 40 mg As kg-1 soil) in soil significantly decreased all the parameters except carotenoid. Both plant height and weight were significantly reduced at 20 mg As kg-1 in soil. Chlorophyll-a and chlorophyll-b content were significantly reduced at 40 mg As kg-1 in soil. Arsenic concentration in plant parts increased significantly at higher As concentration and exceeded the maximum limit of As (0.5 mg kg-1) for vegetables at 20 mg As kg-1 soil and above. Arsenic uptake (µg plant-1) also increased significantly with elevated levels of soil As (40 mg kg-1). Considering the growth performance, I. aquatica should not be recommended to grow where the soil As concentration is 20 mg kg-1 and above.
Lehya formulations for mother and child care in Havyak community of Uttara Kannada district, Karnataka, India
Authors: Hegde Shruthi V , Bhat Pradeep B. , Hegde Ganesh R
Published: October 2019

The period between pregnancy and the child birth is a critical phase in the lives of mothers and newborn babies. In most of the Asian countries including India, the use of medicinal plants, cultural traditions and the diets practiced by the ethnic groups have their age old histories. Present study was carried out to compile the traditional knowledge of the age old practitioners on pre and postnatal remedies. The survey was carried out in the areas of Sirsi, Siddapur and Mundgod taluks of Uttara Kannada district, Karnataka state, India. Medicinal plants were collected and quantitative data analyses like Use Value (UV), Relative frequency citation (Rfc) and Family Importance Value (FIV) have been provided to analyze the importance of reported plants. The study revealed the use of 28 plant species belonging to 19 families. The home remedies for pregnant women are in the form of paste, called ‘Lehya’ in local language. Habit-wise analysis of the plants indicate that herbs are highly used (35.71%) and in most of the case fruits (32.14%) and seeds (25%) are frequently used plant parts in ‘Lehya’ preparation. The most important plant species according to the quantitative data analysis are Cassia sophera, Centella asiatica, Cocos nucifera, Cucumis melo var. acidulus, Curcuma longa, Phoenix dactylifera and Syzygium aromaticum.
Jakość rządzenia i sprawność biurokratyczna a polityka spójności na tle tradycji kulturowej Europy Środkowo-Wschodniej
Authors: Hryniewicz Janusz T.
Published: October 2019

Przedmiotem badań była hipoteza dotycząca wpływu polityki spójności na jakość rządzenia i sprawność biurokratyczną na tle uwarunkowań społeczno-kulturowych. Jednostkami obserwacji były regiony i państwa Europy Środkowo-Wschodniej. Czynniki kulturowe opisano w kategoriach historycznej ewolucji korelatów kapitału społecznego. Obliczenia przeprowadzono w oparciu o międzynarodowe bazy danych dla państw i regionów. Do pomiaru jakości rządzenia użyto wskaźników: QoG (Quality of Gowernace) i regionalnego wskaźnika jakości rządzenia EQI (European Quality Index). Jakość rządzenia mierzona wskaźnikiem QoG jest funkcją kapitału społecznego i wyposażenia w zasoby finansowe administracji publicznej. Zapoczątkowane w 2015 r. w Polsce modyfikacje trójpodziału władzy, nie przełożyły się, jak na razie, na wskaźniki jakości rządzenia. Natomiast na Węgrzech zmiana rządu i późniejszy spadek jakości rządzenia były poprzedzone głębokim kryzysem społeczeństwa obywatelskiego. Polityka spójności została potraktowana jako szczególny przypadek importu kulturowego. Badania regionalne w oparciu o wskaźnik EQI pokazały, że środki polityki spójności przyczyniły się do poprawy funkcjonowania organów administracji publicznej, ale nie wpłynęły na poprawę wskaźnika EQI. Znaczenie zmian czynników społeczno-kulturowych dla poprawy sprawności biurokratycznej jest ambiwalentne. Zmiany czynników zewnętrznych (kapitał społeczny) sprzyjają poprawie funkcjonowania administracji publicznej w krajach Europy Środkowo-Wschodniej. Natomiast styl kierowania będzie stanowił wyraźną barierę wobec tych oddziaływań. Import kulturowy nie spowodował wyraźnych przemian kultury organizacyjnej.
Multi-level governance in local governments in the Federal Republic of Germany
Authors: Balcerek-Kosiarz Marta
Published: October 2019

Samorząd gminny w Niemczech, wykonując zadania publiczne w ramach multilevel governance, pełni najważniejszą rolę w układzie sieciowym. Jako organ państwa inicjuje i zmienia formy koordynacji działań zbiorowych. Głównym problemem, jaki legł u podstaw artykułu jest używanie siatki pojęciowej, występującej w zdekoncentrowanej strukturze administracji publicznej w krajach anglosaskich, do opisu multi-level governance w zdecentralizowanych formach administracji publicznej. Celem głównym artykułu jest zaprezentowanie w jaki sposób koncepcja multi-level governance została dostosowana do specyfiki niemieckiego samorządu gminnego oraz na czym polega jej istota. Celowi głównemu podporządkowano następujące pytania badawcze: Jaka jest różnica w genezie governance w Niemczech w porównaniu do tradycji państw anglosaskich? W jaki sposób są realizowane zadania publiczne w ramach multi-level governance w Niemczech? Jakie są formy organizacyjno-prawne wykonywania zadań publicznych? Artykuł został przygotowany według założeń nowego instytucjonalizmu. W celu zaprezentowania sposobów wykonywania zadań publicznych w koncepcji multi-level governance zastosowano metodę funkcjonalną, która umożliwiła wyłonienie tych zadań, które mogą być realizowano zarówno przez jednostki samorządu terytorialnego, jak i instytucje samorządu gospodarczego. Uzupełniając rozważania zastosowano również metodę instytucjonalną pokazującą specyfikę współpracy samorządu gminnego z innymi podmiotami publicznoprawnymi i prywatnoprawnymi. Z badań nad multi-level governance w Niemczech autorka wyciągnęła trzy wnioski, wokół których powstał artykuł. Po pierwsze, powstanie multi-level governance w Niemczech oparte jest na działaniach odgórnych i następuje od kraju związkowego do gmin (top-down). Tworzenie układu sieciowego wynika wówczas z przekonania władz państwowych o efektywniejszej realizacji zadań publicznych opartej na współpracy z podmiotami prywatnymi, których działania moderowane są przez podmioty władcze. Po drugie, wprowadzenie multi-level governance na poziomie lokalnym poprzedzone jest regional governance na szczeblu krajów związkowych stanowiącą dostosowanie koncepcji governance do specyfiki państwa federalnego. Po trzecie, multi-level governance zostało wprowadzone w strukturę samorządu gminnego za pośrednictwem specjalnego typu zadań publicznych (Gemeinschaftsaufgaben).
The Future of Central Banking
Authors: Yamaoka Hiromi
Published: October 2019

Compared to the history of money and banking, the history of central banking is fairly brief and has been influenced by the development of modern nation states, by the economic environment and by technological advances. Accordingly, on-going innovations in digital technologies and the globalization of the economy are expected to have significant impacts on central banking in the future. Since all the core activities of central banking, such as the issuance of money, the operation of settlement systems, its function as lender of last resort and its monetary policy, are based upon “trust”, its history has been, and its future will also be, closely linked to the most efficient framework in terms of building trust and reflecting changing technological and institutional conditions. Even though digital innovation may influence the styles of central banks in the future, the relevance and effectiveness of their payment and settlement infrastructures, their function as lenders of last resort and their monetary policies will be maintained. Besides, the need for risk-free central bank money will remain strong on account of its capacity to reduce risks in economic transactions, and central banks will have to continue making efforts to meet these demands through the enhancement of the utility of their infrastructure, including real-time gross settlement systems. Regarding central bank digital currencies, many issues require further examination. The future of central banking will be closely interlinked with that of nation states and depends on its capacity to identify the ideal mode of utilizing information and data in the economy.
Modellbasierte Online-Trajektorienplanung für zeitoptimale Rennlinien
Authors: Gundlach Ingmar , Konigorski Ulrich
Published: October 2019

Der Beitrag beschreibt eine zeitoptimale Trajektorienplanung, die eine simultane Quer- und Längsplanung auf Basis eines nichtlinearen Einspurmodells durchführt. Das Optimierungsproblem wird vom Zeit- in den Ortsbereich transformiert. Die Planung wird sowohl für Rundkurse als auch zur zyklischen Planung mit statischen Objekten eingesetzt. Neben der Rundenzeit stehen Komfort und Rechenzeit im Fokus.
Curing behaviors, mechanical properties, dynamic mechanical analysis and morphologies of natural rubber vulcanizates containing reclaimed rubber
Authors: Zhao Xipo , Hu Huan , Zhang Dengke , Zhang Zhen , Peng Shaoxian , Sun Yiming
Published: October 2019

Ground tire rubber (GTR) with crosslinked structure shows hardly any plasticity and processability, giving rise to its relatively poor properties. The thermal-mechanical shearing devulcanization can effectively break the three-dimension crosslinked network structure and restore a certain extent of plasticity and processability. In this work, reclaimed rubber (RR) was obtained by thermal-mechanical shearing devulcanization as a potential filler for natural rubber. The vulcanization process, mechanical properties, microstructure of RR/natural rubber (NR) compounds composites were investigated. It was found that the NR vulcanizates containing 30 phr of RR as filler showed the higher tensile strength and elongation at break. Microstructural characterization analysis on a sample containing 30 phr of RR revealed the existence of strong interactions between the natural rubber matrix and RR, suggesting that RR and NR appeared to be well-matched, undergoing simultaneous curing and forming a continuous phase.
Application of antioxidant and ultraviolet absorber into HDPE: Enhanced resistance to UV irradiation
Authors: Jiang Tiankai , Qi Yanli , Wu Yuchen , Zhang Jun
Published: October 2019

Herein, high density polyethylene (HDPE) matrix was applied as the polymer matrix for its excellent overall performance and low price. In the study, antioxidants (0.5 phr) and ultraviolet absorber (1 phr) were added into the polymer matrix (100 phr) to investigate their influence on UV resistance, respectively. The macroscopic properties and microstructure changes of the samples were both investigated through the characterizations of Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), mechanical properties and thermogravimetric analysis (TGA). This work also conceived the three methods of capturing free radicals generated by photoaging, decomposing peroxides generated by photoaging, and absorbing ultraviolet light to achieve anti-aging effects. The results showed that the UV absorber improves the UV resistance of the material better than the antioxidant. After irradiation for 600 h under the aging condition of 0.51 w/m2@λ = 340 nm, the samples added with UV absorber also still maintain their mechanical properties at a high level. For comparison, the samples added with antioxidants presents poor mechanical properties only after irradiation for 200 h. Besides, the crystallinity of HDPE and HDPE added with antioxidant significantly increased after irradiation, but the crystallinity of HDPE introduced with UV absorber presents slight changes before and after irradiation. Meanwhile, all the irradiated samples also maintained the original excellent thermal stability. According to the obtained results, the aging mechanism was also analyzed.
On a class of critical Robin problems
Authors: Leonardi Salvatore , Papageorgiou Nikolaos S.
Published: October 2019

We consider a nonlinear parametric Robin problem.
In the reaction, there are two terms, one critical and the other locally defined.
Using cut-off techniques, together with variational tools and critical groups, we show that, for all small values of the parameter, the problem has at least three nontrivial smooth solutions all with sign information, which converge to zero in

C
1

⁢

(

Ω
¯

)

{C^{1}(\bar{\Omega})}

as the parameter

λ
→

0
+

{\lambda\to 0^{+}}

.
„Neue Zeitungen“ über Ungarn. Ein frühneuzeitliches Informations- und Unterhaltungsmedium
Authors: Lichnerová Lucia , Špániová Marta
Published: October 2019

„Neue Zeitungen“ sind ein Medium mit unregelmäßiger Periodizität, das sich im 16. Jahrhundert aus dem deutschsprachigen Raum in ganz Europa verbreitete und bis zum Ende des 17. Jahrhunderts dokumentiert ist. Die Veröffentlichung der „Neuen Zeitungen“ stieg mit der Nachfrage der potenziellen Leser nach Informationen über die Ereignisse in Europa und der ganzen Welt. Viele „Neue Zeitungen“ zu ungarischen Ereignissen wurden auf der Grundlage von Korrespondenzen und handgeschriebenen Meldungen erstellt, die entweder direkt an den Drucker oder an einen bekannten Adressaten geschickt wurden. In der Zeit von 1515 bis 1652 lassen sich etwa neunzig erhaltene „Neue Zeitungen“ zu Ereignissen in Ungarn identifizieren. Diese Publikationen stammen von mehr als fünfzig Druckern, die in 29 Städten in Deutschland, Österreich, Frankreich, Schlesien, Böhmen und Ungarn tätig waren. Eine geografische Verknüpfung zwischen dem Ort des Ereignisses, dem Ort der Entstehung des Berichts und dem Ort der Veröffentlichung kann nur in Ausnahmefällen ermittelt werden. Sehr häufig wurden dieselben Zeitungen mit identischen oder fast identischen Inhalten gleichzeitig an verschiedenen Orten veröffentlicht. Häufige Nachdrucke von „Neuen Zeitungen“ sind in vielen Fällen die einzige Informationsquelle über die Existenz von nicht erhaltenen Erstausgaben. „Neue Zeitungen“ wurden hauptsächlich von den Druckern, Verlegern, Verfassern oder Boten vertrieben. „Neue Zeitungen“ zu ungarischen Ereignissen enthielten vor allem politische Berichte, aber auch Nachrichten über Wunder und Naturkatastrophen. „Neue Zeitungen“ können deshalb mit heutigen Boulevardzeitschriften verglichen werden. Die Glaubwürdigkeit der „Neuen Zeitungen“ zu ungarischen Ereignissen wurde mit Hilfe eines vertrauten Autors, Titels, Druckers oder Augenzeugen der beschriebenen Ereignisse verstärkt. Die „Neuen Zeitungen“ erfüllten die Funktion eines Informations-, Bildungs- und Unterhaltungsmediums, aus dem sich später die periodische Presse entwickelte.
Language policy and language planning in mainland Southeast Asia: Myanmar and Lisu
Authors: Bradley David
Published: October 2019

Most nations in mainland Southeast Asia and elsewhere have one national language as a focus of national identity and unity, supported by a language policy which promotes and develops this language. Indigenous and immigrant minority groups within each nation may be marginalized; their languages may become endangered. Some of the official national language policies and ethnic policies of mainland Southeast Asian nations aim to support both a national language and indigenous minority languages, but usually the real policy is less positive. It is possible to use sociolinguistic and educational strategies to maintain the linguistic heritage and diversity of a nation, develop bilingual skills among minority groups, and integrate minorities successfully into the nations where they live, but this requires commitment and effort from the minorities themselves and from government and other authorities. The main focus of this paper is two case studies: one of language policy and planning in Myanmar, whose language policy and planning has rarely been discussed before. The other is on the Lisu, a minority group in Myanmar and surrounding countries, who have been relatively successful in maintaining their language.
Appendix bleeding with painless bloody diarrhea: A case report and literature review
Authors: Chen Wanqun , Qiu Hong , Yang Xiaojun , Zhang Jinwei
Published: October 2019

Appendix bleeding is an uncommon clinical phenomenon. In this article, we reported a case of appendix bleeding with painless bloody diarrhea. With the analysis of clinical features, clinical examination, experimental test and literature review, we diagnosed that the appendix bleeding might be caused by granulomatous appendicitis. This successfully cured case might be a reference for later diagnosis and treatment of appendix bleeding with painless bloody diarrhea.
The crystal structure of poly[(m4-4-bromoisophthalato-κ4
O: O′:O′′:O′′′)zinc(II)], C8H3BrO4Zn
Authors: Chang Xin-Hong
Published: October 2019

C8H3BrO4Zn, monoclinic, P21/c (no. 14), a = 4.7134(4) Å, b = 15.4354(13) Å, c = 12.0064(9) Å, β = 98.942(8)°, V = 862.89(12) Å3, Z = 4, R
gt(F) = 0.0445, wR
ref(F
2) = 0.1193, T = 292.67(10) K.
Crystal structure of cyclo[tetra(μ2-cyanido)-tetracyanido-bis(1,4,7,10-tetraazacyclododecane-κ4
N,N′,N′′,N′′′)dinickel(II)dipalladium(II)] hexahydrate, C24H52N16Ni2O6Pd2
Authors: Ha Kwang
Published: October 2019

C24H52N16Ni2O6Pd2, monoclinic, P21/c (no. 14), a = 8.6416(3) Å, b = 14.2237(5) Å, c = 15.5573(5) Å, β = 93.8054(12)°, V = 1908.02(11) Å3, Z = 2, R
gt(F) = 0.0312, wR
ref(F
2) = 0.0915, T = 223(2) K.
Hemispheric Asymmetry of Globus Pallidus Relates to Alpha Modulation in Reward-Related Attentional Tasks
Authors: Mazzetti Cecilia , Staudigl Tobias , Marshall Tom R. , Zumer Johanna M. , Fallon Sean J. , Jensen Ole
Published: October 2019

Whereas subcortical structures such as the basal ganglia have been widely explored in relation to motor control, recent evidence suggests that their mechanisms extend to the domain of attentional switching. We here investigated the subcortical involvement in reward related top-down control of visual alpha-band oscillations (8–13 Hz), which have been consistently linked to mechanisms supporting the allocation of visuospatial attention. Given that items associated with contextual saliency (e.g., monetary reward or loss) attract attention, it is not surprising that the acquired salience of visual items further modulates. The executive networks controlling such reward-dependent modulations of oscillatory brain activity have yet to be fully elucidated. Although such networks have been explored in terms of corticocortical interactions, subcortical regions are likely to be involved. To uncover this, we combined MRI and MEG data from 17 male and 11 female participants, investigating whether derived measures of subcortical structural asymmetries predict interhemispheric modulation of alpha power during a spatial attention task. We show that volumetric hemispheric lateralization of globus pallidus (GP) and thalamus (Th) explains individual hemispheric biases in the ability to modulate posterior alpha power. Importantly, for the GP, this effect became stronger when the value saliency parings in the task increased. Our findings suggest that the GP and Th in humans are part of a subcortical executive control network, differentially involved in modulating posterior alpha activity in the presence of saliency. Further investigation aimed at uncovering the interaction between subcortical and neocortical attentional networks would provide useful insight in future studies.

SIGNIFICANCE STATEMENTWhereas the involvement of subcortical regions into higher level cognitive processing, such as attention and reward attribution, has been already indicated in previous studies, little is known about its relationship with the functional oscillatory underpinnings of said processes. In particular, interhemispheric modulation of alpha band (8–13 Hz) oscillations, as recorded with magnetoencephalography, has been previously shown to vary as a function of salience (i.e., monetary reward/loss) in a spatial attention task. We here provide novel insights into the link between subcortical and cortical control of visual attention. Using the same reward-related spatial attention paradigm, we show that the volumetric lateralization of subcortical structures (specifically globus pallidus and thalamus) explains individual biases in the modulation of visual alpha activity.
Wide. Fast. Deep: Recent Advances in Multiphoton Microscopy ofIn VivoNeuronal Activity
Authors: Lecoq Jérôme , Orlova Natalia , Grewe Benjamin F.
Published: October 2019

Multiphoton microscopy (MPM) has emerged as one of the most powerful and widespread technologies to monitor the activity of neuronal networks in awake, behaving animals over long periods of time. MPM development spanned across decades and crucially depended on the concurrent improvement of calcium indicators that report neuronal activity as well as surgical protocols, head fixation approaches, and innovations in optics and microscopy technology. Here we review the last decade of MPM development and highlight howin vivoimaging has matured and diversified, making it now possible to concurrently monitor thousands of neurons across connected brain areas or, alternatively, small local networks with sampling rates in the kilohertz range. This review includes different laser scanning approaches, such as multibeam technologies as well as recent developments to image deeper into neuronal tissues using new, long-wavelength laser sources. As future development will critically depend on our ability to resolve and discriminate individual neuronal spikes, we will also describe a simple framework that allows performing quantitative comparisons between the reviewed MPM instruments. Finally, we provide our own opinion on how the most recent MPM developments can be leveraged at scale to enable the next generation of discoveries in brain function.
PERFORMANCE OF EINKORN (Triticum monococcum L.) FLOUR IN THE MANUFACTURE OF TRADITIONAL TURKISH NOODLE
Authors: LEVENT Hacer
Published: October 2019

Wheat flour used in traditional
Turkish noodle formulation was replaced with einkorn wheat flour (EWF) at 0,
20, 40, 60, 80 and 100% levels. The effects of EWF on some properties of noodle
samples were evaluated. The use of EWF resulted in significant increases in the
ash, protein, total phenolic content and antioxidant activity of noodle (P<0.05). Volume and weight increase values increased as EWF ratio
increased. The lowest cooking loss value (5.85%) was obtained in noodle
containing 100 EWF%.  Ca, Fe, Cu and Mg
contents of noodle samples increased 1.41, 3.27, 1.45 and 2.66 times at 100%
EWF compared to control sample. The use of 100% EWF decreased the taste and
chewiness scores of cooked noodle. Considering the physicochemical, sensory
properties and cooking quality of the samples, it can be concluded that the EWF
can be used successfully up to 60% level in the Turkish noodle formulation.
“No Amount of Baths Is Gonna Make You Feel Better”: Seeking Balance, Wholeness, and Well-being in Everyday Self-Care
Authors: Adams Quinci
Published: October 2019

Recently, the concept of “self-care” has shifted from the sphere of biomedicine into popular discourse; rather than indicating the practice of maintaining physical health, the term has come to represent a set of broader and more commonplace practices aimed at achieving balance, wholeness, and overall well-being. Drawing from interviews and participant observation with young adult respondents both in college and recently graduated, this study explores what it means to practice this type of “everyday self-care.” Those who practice everyday self-care do so to seek out a holistic sense of happiness and well-being; they value self-care that engages their “whole” self – one conceptualized as made up of both mind and body. They strive for balance in tensions between self-control and indulgence, long-term well-being and immediate gratification, and selfishness and community. Self-care cannot be summed up in a list of activities or practices; rather, it necessitates an ongoing production of moral, economic, and social meanings.
Genomics Analysis of L-DOPA Exposure inDrosophila sechellia
Authors: Lanno Stephen M , Lam Ivy , Drum Zachary , Linde Samuel C , Gregory Sara M , Shimshak Serena J , Becker Mariel V , Brew Kerry E , Budhiraja Aashli , Carter Eliza A , Chigweshe Lorencia , Collins Keagan P , Earley Timothy , Einstein Hannah L , Fan Angela A , Goss Sarah S , Hagen Eric R , Hutcheon Sarah B , Kim Timothy T , Mitchell Mackenzie A , Neri Nola R , Patterson Sean E , Ransom Gregory , Sanchez Guadalupe J , Wiener Bella M , Zhao Dacheng , Coolon Joseph D
Published: October 2019

Drosophila sechellia is a dietary specialist fruit fly that evolved from a generalist ancestor to specialize on the toxic fruit of Morinda citrifolia. This species pair has been the subject of numerous studies where the goal has largely been to determine the genetic basis of adaptations associated with host specialization. Because one of the most striking features of M. citrifolia fruit is the production of toxic volatile compounds that kill insects, most genomic studies in D. sechellia to date have focused on gene expression responses to the toxic compounds in its food. In this study, we aim to identify new genes important for host specialization by profiling gene expression response to 3,4-dihydroxyphenylalanine (L-DOPA). Recent work found it to be highly abundant in M. citrifolia, critical for reproductive success of D. sechellia, and supplementation of diet with the downstream pathway product dopamine can influence toxin resistance phenotypes in related species. Here we used a combination of functional genetics and genomics techniques to identify new genes that are important for D. sechellia ecological adaptation to this new niche. We show that L-DOPA exposure can affect toxin resistance phenotypes, identify genes with plastic responses to L-DOPA exposure, and functionally test an identified candidate gene. We found that knock-down of Esterase 6 (Est6) in a heterologous species alters toxin resistance suggesting Est6 may play an important role in D. sechellia host specialization.
Genome Assemblies of Two Rare Opportunistic Yeast Pathogens:Diutina rugosa(syn.Candida rugosa) andTrichomonascus ciferrii(syn.Candida ciferrii)
Authors: Mixão Verónica , Saus Ester , Hansen Antonio Perez , Lass-Florl Cornelia , Gabaldón Toni
Published: October 2019

Infections caused by opportunistic yeast pathogens have increased over the last years. These infections can be originated by a large number of diverse yeast species of varying incidence, and with distinct clinically relevant phenotypic traits, such as different susceptibility profiles to antifungal drugs, which challenge diagnosis and treatment. Diutina rugosa (syn. Candida rugosa) and Trichomonascus ciferrii (syn. Candida ciferrii) are two opportunistic rare yeast pathogens, which low incidence (< 1%) limits available clinical experience. Furthermore, these yeasts have elevated Minimum Inhibitory Concentration (MIC) levels to at least one class of antifungal agents. This makes it more difficult to manage their infections, and thus they are associated with high rates of mortality and clinical failure. With the aim of improving our knowledge on these opportunistic pathogens, we assembled and annotated their genomes. A phylogenomics approach revealed that genes specifically duplicated in each of the two species are often involved in transmembrane transport activities. These genomes and the reconstructed complete catalog of gene phylogenies and homology relationships constitute useful resources for future studies on these pathogens.
A clinical and radiographical comparison of buccolingual crestal bone changes after immediate and delayed implant placement
Authors: Amin Viraj , Kumar Santosh , Joshi Surabhi , Hirani Tanvi , Shishoo Deepak
Published: October 2019

Aim. The study aims to clinically and radiographically compare the bucco-lingual crestal bone changes after immediate and delayed placement of implants.

Methods. Two groups that consisted of fifty implants were considered for this study. In group A the implants were placed immediately post extraction, whereas, in group B implants placement were delayed by four to six weeks. All the implants were submerged within the alveoli confines. Bone grafts were only placed if the jumping distance was more than 1.5 mm. Barrier membrane was not placed in any of the cases. Bucco-lingual width was measured at the time of implant placement and during abutment placement after four to six weeks. Primary flap closure was ensured in all the cases.

Results. Thirty-one implants were placed in the mandible and nineteen were placed in the maxilla. All the implants achieved osseointegration. Immediate implant group showed a mean width of 8.80 mm (SD2.280) at the time of implant placement whereas, 7.60 mm (SD 1.871) after six months. Delayed implant group showed a mean width of 8.40 mm (SD1.673) at the time of implant placement, and 7.40 mm (SD 1.658) after six months. Intragroup showed statistically significant data (P<0.05). When the intergroup comparison of group 1 and group 2 was made at implant placement day and abutment placement day, it was found to be statistically non-significant.

Conclusion. This study suggests that circumferential defect heals on itself without any guided bone regeneration in both the groups. The data suggests that the healing in both the group were equally good. The equally good results suggest placing the implant immediately post extraction. This saves the cost, time and most importantly the need for an extra surgery.
Diagnostic dilemma in soft tissue swelling over finger
Authors: Nagpal Ruchi , Ahuja Arvind
Published: October 2019

Myopericytoma is a benign tumor that shows a pericytic line of differentiation. The lesion is generally located in the dermis and subcutaneous tissue and has a predilection for distal extremities, but may be found in any part of the body. We present a case of 48-year old male who came with painful swelling in right middle finger for the past 2 years. Histopathology showed proliferation of spindle-shaped cells exhibiting a hemangio-pericytomatous pattern with various sized vessels lined by flattened endothelium and surrounded by a concentric arrangement of spindle-shaped cells. Tumor cells show membranous positivity for smooth muscle actin but negative for desmin and CD 34. Hence diagnosis of intravenous myopericytoma was established.
Pengaruh Motivasi Pengurus DKM Mesjid dan Kepemimpinan Ketua DKM Mesjid terhadap Kompetensi Manajerial Ketua DKM Mesjid di Kota Bogor
Authors: Hidayatulloh M Taufik
Published: October 2019

Penelitian ini membahas tentang pengaruh motivasi pengurus DKM mesjid dan kepemimpinan ketua DKM mesjid terhadap kompetensi manajerial ketua DKM mesjid. Penelitian dilakukan dari bulan Mei-November 2015 di Kota Bogor, Provinsi Jawa Barat. Pengurus DKM mesjid jami merupakan populasi yang diamati pada penelitian ini yang berjumlah 456 orang. Sampel ditetapkan tiap kecamatan dengan menggunakan teknik proportionate stratified random sampling yang berjumlah 215 orang. Data dikumpulkan dengan menggunakan kuesioner, observasi, wawancara semi terstruktur dan studi dokumentasi. Analisis statistik menggunakan analisis regresi linier berganda. Hasilnya menunjukkan bahwa motivasi pengurus DKM mesjid berada pada kategori sedang dengan dorongan berafiliasi menempati skor lebih tinggi dibandingkan dengan subpeubah motivasi lainnya, kepemimpinan ketua DKM mesjid berada pada kategori sedang dengan skor tertinggi ada pada kemampuan berhubungan dengan orang lain dan skor terendah ada pada kemampuan teknis, kompetensi manajerial ketua DKM mesjid menurut penilaian responden secara umum berada pada kategori sedang dengan kompetensi kerjasama internal dinilai paling tinggi. Hasil analisis regresi linier bergdana menunjukkan bahwa motivasi pengurus DKM mesjid dan kepemimpinanan ketua DKM mesjid memberikan pengaruh nyata positif terhadap kompetensi manajerial ketua DKM mesjid.