bluuebunny/crossref_metadata_2025 huggingface dataset:
Drugit: Crowd-sourcing molecular design of non-peptidic VHL binders
Authors: Scott Thomas , Smethurst Christian Alan Paul , Westermaier Yvonne , Mayer Moriz , Greb Peter , Kousek Roland , Biberger Tobias , Bader Gerd , Jandova Zuzana , Schmalhorst Philipp S. , Fuchs Julian E. , Magarkar Aniket , Hoenke Christoph , Gerstberger Thomas , Combs Steven A. , Pape Richard , Phul Saksham , Kothiwale Sandeepkumar , Bergner Andreas , Waterson Alex G. , Players Foldit , Weinstabl Harald , McConnell Darryl B. , Böttcher Jark , Meiler Jens , Moretti Rocco
Published: May 2023

Given the role of human intuition in current drug design efforts, crowd-sourced 'citizen scientist' games have the potential to greatly expand the pool of potential drug designers. Here, we introduce ‘Drugit', the small molecule design mode of the online ‘citizen science’ game Foldit. We demonstrate its utility for design with a use case to identify novel binders to the von Hippel Lindau E3 ligase. Several thousand molecule suggestions were obtained from players in a series of 10 puzzle rounds. The proposed molecules were then evaluated by in silico methods and by an expert panel and selected candidates were synthesized and tested. One of these molecules, designed by a player, showed dose-dependent shift perturbations in protein-observed NMR experiments. The co-crystal structure in complex with the E3 ligase revealed that the observed binding mode matched in major parts the player’s original idea. The completion of one full design cycle is a proof of concept for the Drugit approach and highlights the potential of involving citizen scientists in early drug discovery.
Revising the formation of β-hematin crystals from hemin in aqueous-acetate medium containing chloroquine: modeling the kinetics of crystallization and characterizing their physico-chemical properties
Authors: Leidy J. Herrera , Cristian A. Parra , Daniel Coronado , Perez Valentina , Zapata Julian A , Pabón Adriana L. , Lopez-Acevedo Olga , García Karen E. , Barrero César A.
Published: May 2023

We investigated the kinetics of conversion of hemin to β-hematin in aqueous-acetate medium in absence and in presence of two concentrations of chloroquine by using eleven reported kinetic equations. The two best kinetic equations are the combination of order 1 and Avrami and the combination of second order and logistic equations, based on the statistical parameters variance and overall errors. The best fitted equations are composed of two terms from which we model the formation of β-hematin as the result of two processes: the availability of reactive precursors and the formation of nucleation and growth sites. The crystals exhibit needle-like morphologies of about 760 nm long and 140 nm wide. However, the increment of chloroquine favors the formation of crystal twinning with non-homogenous distribution, crystals with lower sizes of similar heights and widths, and crystals symmetrically tapered at the ends of the needles. The lattice volumes, obtained from Rietveld analysis of powder X-ray diffraction patterns, were not regularly affected by chloroquine. The main IR absorption bands did not appreciably change in positions nor in intensities with varying chloroquine concentration. However, important changes were observed in the 2000-4000 cm-1 region. We used Density Functional Theory calculations to understand these changes.
On degree of approximation of conjugate series of a Fourier series by product summability
Authors: Mahendra Misra  , B. P. Padhy  , Dattaram Bisoyi  , U. K. Misra
Published: May 2023

In this paper a theorem on degree of approximation of a function $f \in \operatorname{Lip}(\alpha, r)$ by product summability $(E, q)\left(\bar{N}, p_n\right)$ of conjugate series of Fourier series associated with $f$ has been proved.
Application of random fixed point theorems in solving nonlinear stochastic integral equation of the Hammerstein type
Authors: Debashis Dey  , Mantu Saha
Published: May 2023

In the present paper, we apply random analogue Kannan fixed point theorem [10] to analyze the existence of a solution of a nonlinear stochastic integral equation of the Hammerstein type of the form$$x(t ; \omega)=h(t ; \omega)+\int_S k(t, s ; \omega) f(s, x(s ; \omega)) d \mu(s)$$where $t \in S$, a $\sigma$-finite measure space with certain properties, $\omega \in \Omega$, the supporting set of a probability measure space $(\Omega, \beta, \mu)$ and the integral is a Bochner integral.
Analysis of Forecast and Early Warning of Flood in Medium and Small Rivers
Authors: Cai Yaxi , Yang Xiaodong , Zhao Binhua
Published: May 2023

Flooding of small and medium rivers is caused by environmental factors like rainfall and soil loosening. With the development and application of technologies such as the Internet of Things and big data, the disaster supervision and management of large river basins in China has improved over the years. However, due to the frequent floods in small and medium-sized rivers in our country, the current prediction and early warning of small and medium-sized rivers is not accurate enough; it is difficult to realize real-time monitoring of small and medium-sized rivers, and it is also impossible to obtain corresponding data and information in time. Therefore, the construction and application of small and medium-sized river prediction and early warning systems should be further improved. This paper presents an analysis and discussion on flood forecasting and early warning systems for small and medium-sized rivers in detail, and corresponding strategies to improve the effect of forecasting and early warning systems are proposed.
Integração e diversidade: articulações entre a Etnomatemática e as questões étnico-raciais
Authors: Diogenes Adriana Lúcia Brandão , Almeida Shirley Patrícia Nogueira de Castro e
Published: May 2023

Objetivamos, aqui, analisar o que dizem as teorias acerca da Etnomatemática, suas práticas, bem como a legislação brasileira sobre as questões étnico-raciais e a Educação Quilombola. A construção do nosso aporte teórico foi subsidiada por autores que discutem a Educação Matemática, como D’Ambrosio (2009, 2019); as questões das relações raciais, como Gomes (1997, 2005) e Munanga (2001); além da legislação brasileira (1988, 1996, 1999, 2003, 2004, 2007, 2012, 2015, 2018). Os resultados apontaram que é complexo abordar as relações étnico-raciais e as diferentes maneiras de construir conhecimento, pois, mesmo em instituições de ensino situadas em Comunidades Quilombolas e havendo determinações legais que as amparem, as temáticas relacionadas aos saberes e fazeres matemáticos afro-brasileiros ainda são pouco tratadas. Nesse sentido, buscamos ressaltar como o Programa Etnomatemática pode favorecer tal discussão, a partir do lugar que reserva aos saberes e fazeres matemáticos das populações tradicionais dessas instituições educacionais.
Representações sociais e formação docente em Química
Authors: Fonseca Carlos Ventura
Published: May 2023

São investigadas as representações sociais de estudantes universitários da área de Química, matriculados em uma disciplina denominada Introdução ao Campo da Docência, acerca de temas concernentes ao magistério. Foi realizada a coleta de dados via questionário e a interpretação destes ocorreu por meio de análise de conteúdo. As reflexões construídas têm potencial para aperfeiçoar o planejamento e o desenvolvimento da formação docente, com foco reorientado para a racionalidade crítica.
formação continuada para uma educação humanizadora
Authors: Dalla Valle Paulo Roberto , Strieder Roque , Delgado Ana Cristina Coll
Published: May 2023

O presente artigo constitui-se em um ensaio teórico, com abordagem crítico-reflexiva, e tem por objetivo, refletir sobre os desafios e possibilidades de pensar e propor coletivamente a formação continuada para uma educação na perspectiva humanizadora. Aprofunda-se o olhar sobre as práticas de formação estabelecendo nexos com questões subjetivas, intersubjetivas, alteridade, as vivências e experiências formativas e aprendentes, como caminhos e possibilidades de pensar outros horizontes e perspectivas para além dos tradicionais processos de formação. Reconhece-se nesta perspectiva um potencial gerador de inúmeras e tantas outras possibilidades de vir a ser e reconhecer-se no outro através da formação continuada.
Formação de professores surdos em Rio Branco, Acre
Authors: Santos Junior João Renato dos , Sousa Alexandre Melo de
Published: May 2023

Este artigo apresenta uma pesquisa sobre a formação de professores surdos na cidade de Rio Branco, Acre, a partir da perspectiva dos sujeitos (docentes) surdos. Serão descritas as trajetórias de formação de seis participantes surdos (três homens e três mulheres). O estudo é do tipo aplicado, empírico e de abordagem qualitativa. Os objetivos são de natureza analítico-descritiva, uma vez que analisamos as falas dos participantes surdos quanto aos seus processos de formação e os desafios enfrentados. A fundamentação teórica tomou por base os estudos de Mendes e Pereira (2017), Nóvoa (1995; 2019); Vilhalva (1994), Quadros e Stumpf (2014) e Stumpf e Linhares (2019). Os resultados mostraram que a trajetória foi permeada de lutas e esforços para vencer os desafios, especialmente quanto à comunicação. O desconhecimento da Libras nos espaços de formação é uma barreira para os surdos, e a inclusão fica na intenção. Com isso, percebemos que há ainda muito a avançar no que diz respeito à formação de professores surdos no estado do Acre, mas os caminhos estão se abrindo e o docente surdo está, pouco a pouco, construindo seu protagonismo na educação de surdos, a partir de uma formação consolidada em áreas específicas da Libras, nas formações em nível de pós-graduação, nas aprovações em concursos públicos para o magistério básico e superior, nas presenças em espaços sociais e políticos diversos, entre outros. Desse modo, vislumbramos uma formação mais humana, inclusiva e bicultural, em que o surdo encontre espaço para a valorização da sua cultura e a consolidação da sua identidade (humana e profissional).
Rethinking assessment in teacher education
Authors: Lopes Juliana Crespo , Stará Jana , Krčmarová Tereza
Published: May 2023

This action research in education discusses the relationship between learning assessments and students' mental health, focusing on a Teacher Education course at a university in the Czech Republic. Institutional and relational practices are identified to foster better assessment opportunities.
BNCC e BNC-formação
Authors: Santos Elaine Fernanda dos , Silva Maria do Socorro Ferreira da , Santos Sindiany Suelen Caduda dos
Published: May 2023

O processo de formação de professores tem sido redesenhado para atender as exigências impostas pela Base Nacional Comum Curricular (BNCC). Este artigo, de natureza teórica, objetiva discutir como a BNC-formação contempla o desenvolvimento das competências gerais e específicas, articuladas com as práticas pedagógicas docentes, de modo a garantir a construção de aprendizagens essenciais preconizadas pela BNCC e possibilitar a democratização do ensino e a educação integral. Para isso, são discutidos os pressupostos teórico-metodológicos desses documentos que orientam os currículos da educação básica e formação dos professores, fazendo articulação com as práticas pedagógicas para o ensino integral e humano. Por meio da discussão, é possível refletir sobre uma série de encontros e desencontros entre a BNCC e BNC-formação, no que diz respeito ao desenvolvimento de competências, habilidades, educação integral, formação humana e saberes experienciais. Defendemos ao final que, para alcançar o processo de ensino e aprendizagem, que considere as singularidades dos estudantes, é basilar pensar na formação humana e democrática.
Conceito de práticas pedagógicas transformadoras
Authors: Da Costa Maria Adélia , Santos Guerra Lícia Flávia , Seabra Filipa
Published: May 2023

Apresenta-se neste manuscrito percepções docentes e discentes sobre práticas pedagógicas desenvolvidas num curso técnico, visando a convergência destas percepções para a formação do pensamento crítico, do sujeito autônomo e criativo, que associamos ao conceito de práticas pedagógicas transformadoras. Trata-se de uma pesquisa qualitativa e descritiva cujos resultados indicaram que a maioria dos professores sente necessidade de formação continuada para aprimoramento de suas práticas pedagógicas. Na subjetividade dos discentes, observou-se que eles valorizavam mais recursos didáticos diversificados que estratégias de ensino pautadas pelo requerimento do papel autônomo no processo de aprendizagem. Infere-se que os alunos apreciam aulas tradicionais que exigem pouco esforço cognitivo.
Fundação Lemann e o capital educador
Authors: Raimann Elizabeth Gottschalg , Castro Leislainy  Moraes , Machado Bruna Ferreira Bispo
Published: May 2023

O artigo problematiza quem educa o educador no contexto capitalista. Mediante pesquisa exploratória, busca-se analisar as conexões entre a Fundação Lemann e oito universidades norte-americanas na oferta da formação continuada de professores, nível pós-graduação stricto sensu. A análise aponta que as parcerias entre a fundação e as universidades objetivam formar um corpo técnico-político alinhado às diretrizes do capital, propalando o ideário empresarial na educação. Esta fundação se constitui no que se denomina por Aparelho Privado de Hegemonia empresarial no campo educacional desde a década de 2000, apoiada pelos governos federais de lá para cá.
Educação para estudantes surdos no Brasil
Authors: Hojas Viviani Fernanda , Silva Rubia Carla Donda da
Published: May 2023

Orientado pelos pressupostos bakhtinianos, o artigo objetiva compreender o embate em torno da educação para estudantes surdos gerado na Conferência Nacional de Educação, com repercussões no Plano Nacional de Educação e na Lei de Diretrizes e Bases da Educação Nacional.
Formação de professores e estágios supervisionados no âmbito da residência pedagógica
Authors: Gomes Yana Liss Soares , De Araújo Souza Jordânia
Published: May 2023

O presente artigo apresenta uma análise das contribuições do projeto piloto de Residência Pedagógica (RP) da Universidade Federal de Alagoas (UFAL), a partir da ótica dos preceptores participantes. Para esta discussão utilizou-se a análise do relatório parcial do Programa Residência Pedagógica (PRP), a partir de quatro indicadores: de quantidade, de processo, de formação e de qualidade. Os dados revelam que na avaliação dos preceptores há o destaque para o grande potencial das propostas de estágios supervisionados da RP para a formação docente (inicial e continuada).
PRELIMINARY RESULTS OF LABORATORY INVESTIGATIONS OF THE EVOLUTION OF NON-FRONTAL EDDIES IN A TWO-LAYERED ROTATING FLUID
Authors: Zatsepin A. G. , Elkin D. N. , Shvartsman D. R.
Published: May 2023

In this work, by means of laboratory modeling, the patterns of evolution (baroclinic instability and/or viscous degeneration) of mesoscale non-frontal baroclinic eddies, or open ocean eddies (without a core with the water of different density) were revealed. The experiment was provided in a two-layer salinity-stratified aquatic environment in a cylindrical tank located on a rotating platform. Using the original application of the “cylinder method”, single axisymmetric cyclonic and anticyclonic eddies were produced in the upper layer, and their evolution was traced over 100 or more platform rotation periods (laboratory days). It has been established that the vortices lose their stability if the value of the defining parameter representing the ratio of the Burger and Froude numbers is less than the critical one. In this case, eddies either fall apart into two or more secondary vortices (strong instability) or acquire an elongated shape (weak instability). The slope of the bottom and its roughness increase the stability of eddies. For values of the determining parameter greater than the critical one, the vortices are stable and gradually degenerate due to viscous friction. In the case of a large difference in salinity (density) between the layers, the bottom roughness does not have a significant effect on the rate of upper layer eddy damping, which, apparently, is determined by the friction in this layer. A parametrization is proposed that describes the exponential law of eddy decay, which is tested on the example of the Black Sea mesoscale eddy.
SCIENCE AND POETRY: TO THE 90th ANNIVERSARY OF ALEXANDER GORODNITSKY
Authors: Palshin N. A. , Shishkina N. A.
Published: May 2023

A brief summary of the life path and main scientific works in the field of geology and geophysics of the ocean A. M. Gorodnitsky – geophysicist, doctor of geological and mineralogical sciences (1982), professor (1991), academician of the Russian Academy of Natural Sciences (1993), Honored Scientist of the Russian Federation (2005), chief researcher of the Laboratory of Geophysical Fields, an interesting and versatile gifted person – also widely known as a poet, songwriter and marine painter.
ANALYSIS OF T, S-CHARACTERISTICS OF THE ATLANTIC WATER MASS IN THE EURASIAN BASIN USING THE CLUSTER METHOD
Authors: Lyzhkov D. A. , Zhurbas N. V. , Kuzmina N. P.
Published: May 2023

Cluster analysis was performed using CTD data from transects across continental slope of the Eurasian Basin collected within the NABOS (Nansen and Amundsen Basins Observing System) project in 2002–2015. The most commonly used k-means clustering method was applied for calculations. Two cases were considered: division into two and three clusters. The identified clusters which united points on the θ, S-diagrams (θ, S are potential temperature and salinity, respectively) satisfactorily corresponded to the θ, S-values of the Fram and Barents branches of the Atlantic water. For each cluster the thermohaline characteristics of centroids (cluster centers) were calculated, that is, the average values at the same time of temperature, salinity and potential density of each water mass. The thermohaline characteristics of centroids, estimated from the available data obtained in different years of observation, were presented in θ, S-coordinates and θ, σ-coordinates (σ is potential density). Additionally, dependences of temperature, salinity, and potential density of centroids on the year of observation were analyzed. The final results made it possible to obtain estimates of the average thermohaline characteristics of Atlantic water in different years of observation and the variability of these estimates from year to year. In particular, it was found that the values of the average thermohaline characteristics of the AW indicated a strong warming and salinization of the AW in 2006–2009 (sections along 126° E), and the response to warming was observed in all AW clusters. An interpretation of the obtained results was given. Approaches to the choice of the most optimal method of cluster analysis were considered. The results of estimating the influence of temperature and salinity variability ranges in the analyzed CTD data on the accuracy of centroids evaluations were presented.
PLANKTONIC AND BENTHIC COMMUNITIES OF THE SOUTHEASTERN PART OF THE BALTIC SEA IN THE SUMMER PERIOD 2018–2019
Authors: Aleksandrov S. V. , Gusev A. A. , Semenova A. S.
Published: May 2023

During the expeditions in July 2018 and 2019 data were obtained on the state of summer plankton and benthos over the entire Russian water area in the southeastern part of the Baltic Sea. The highest abundance of phytoplankton (in terms of chlorophyll “a”) is typical for the coastal region, where it reaches the eutrophic state, and decreases in the seaward zone to the mesotrophic state. Brackish water conditions determined a rather small number of species of zooplankton (36 taxa) and zoobenthos (40 taxa), including invading species (4 in zooplankton and 6 in benthos). Copepoda dominated in zooplankton in the deep-water zone, while the proportion of Cladocera and Rotifera increased in the coastal zone. The abundance and biomass of zooplankton corresponded to the maximum level observed in recent years in the SouthEastern Baltic. Zooplankton was more abundant from the coast to depths of 40 m, as a result, the best feeding conditions for planktophagous fish extended at this area. In benthos, Polychaeta and Bivalvia dominated in abundance, and Bivalvia dominated in biomass. The hydrological conditions in the Russian zone determine the development of zoobenthos in two regions separated by the Gdansk depression, which is characterized by benthic “desert” conditions. The largest region extends from the coast to depths of 70–80 m, and the second – in the deep northwestern part and is confined to the Gdansk-Gotland Sill. High abundance and biomass of zoobenthos are characteristic of the Gdansk basin down to depths of 60 m, where favorable conditions are formed for benthophage fish. The species composition and abundance of zoobenthos on the Gdansk-Gotland Sill much lower and is determined by the presence of North Sea waters inflows, in particular, in 2019 there was an increase in the abundance and distribution of benthos as a result of the inflow of North Sea waters.
How Many Likes?
Authors: De Moura Domingos Wendell , Souza Silva Adrielly , Freitas da Costa Marconi , Gomes Fialho Regina Gabriela
Published: May 2023

The aim of this study was to measure the influence of Electronic Word of Mouth (eWOM), Social Return (SR) and Symbolic Image (SI) on the intention to visit a conspicuous tourist destination. The research had a quantitative approach; thus, data were collected through an online survey and the analysis realized by multiple linear regression. The results revealed that eWOM and SI have no influence on the intention to visit a destination. These findings are not in line with most academic researches, but may be associated with the degree of intangibility of tourism activity and the subjectivity of the individual consumer experience. SR demonstrated a positive influence on the intention to visit a conspicuous destination. Such result is congruent with and reinforces the findings obtained by previous researches on consumer behavior. The main contribution of this study consists in confirming the influence of social media on the intention to visit a tourism destination, in search of visibility, distinction and social prestige. Travel has become a tool for displaying status.
Marketing Strategies to Achieve and Promote Events at Brazilian Conventions & Visitors Bureau
Authors: Ferreira Austregesilo Williany Loren Gaia , Soares Jakson Renner Rodrigues , Macedo Castro Gabriel Larissa Paola , Perinotto André Riani Costa
Published: May 2023

The objective of this study is to identify the Marketing strategies used by the Conventions&Visitors Bureau (CVBs) to attract and retain customers. For the preparation of this study, the Delphi Method was applied using information provided by informants selected from CVB specialists registered at UNEDESTINOS. Based on the results of this research, the strengths, and critics of the CVBs performance are exposed, in addition to mapping the points to be improved and allowing for proposals for solutions and improvement in the CVBs performance to attract and promote events and customer loyalty. Thus, this work brings to the light of CVBs throughout Brazil the need to always innovate in their working methods to, through customer loyalty, obtain a greater reach of business, ensuring the stability of events and the viability of destinations by through the responsible exploitation of regional resources and wealth to attract and promote events.
Evaluasi aktivitas penyembuhan luka menggunakan krim campuran ekstrak teripang laut dan kunyit
Authors: Alpayet Rahmat , Mustika Aulia Andi , Rahma Anisa , Andriyanto  , Sutardi Lina Noviyanti
Published: May 2023

Background: Skin is a layer of tissue from body that covers and protects the body from the danger that comes from outside and the environment. Skin is very susceptible to trauma, which is a cut wound.  Objective: The purpose of the study was to determine the effectiveness of the mixture from sea cucumber and turmeric extract in cream dosage on rat’s cut wounds. Methods: This study used 15 white rats which were given a cut and the treatments of mixed cream with the different concentrations. The treatments were given by to dab the mixed cream on the wound area each day. The wound healing was observed on days 1, 7, 14 and 21, then the researchers gave scores on those wounds. The researcher measured the wound healing through the acceleration parameters of wound closure and inflammation reduction. Results: The results of this study showed that the rats wound completely closed on all area treatments and also showed that the healing time is faster than those who did not receive treatment.  Conclusion: This result indicates that sea cucumber and turmeric extract have the potential and effective for heals the wounds and then can be used as an alternative for wound medicine.
Penerapan Strategi Pembelajaran REACT Untuk Meningkatkan Kemampuan Berpikir Kritis Siswa dalam Pembelajaran Sosiologi Pada Siswa Kelas XI IPS 1 di SMA Negeri 1 Lingsar
Authors: Puspa Dewi Ni Wayan Ayu , Suryanti Ni Made Novi , Nursaptini Nursaptini
Published: May 2023

Penelitian ini bertujuan untuk meningkatkan kemampuan berpikir kritis siswa dalam pembelajaran sosiologi dengan penerapan strategi pembelajaran REACT pada peserta didik kelas XI IPS 1 di SMA Negeri 1 Lingsar. Metode penelitian ini merupakan penelitian tindakan kelas (PTK). Penelitian ini dilakukan selama dua siklus, masing-masing siklus terdapat dua kali pertemuan dan memiliki 4 langkah-langkah dalam penelitian yaitu: (1) perenanaan; (2) tindakan; (3) observasi; (4) refleksi. Analisa data pada penelitian ini menggunakan reduksi data, pemaparan data dan menarik kesimpulan. Instrumen dalam penelitian ini dengan observasi, tes dan dokumentasi. Berdasarkan hasil penelitian dari siklus I, jumlah indikator yang muncul dalam observasi proses pembelajaran dengan penerapan strategi REACT sebanyak 32 indikator (91%) dari jumlah total 35 indikator. Data kemampuan berpikir tingkat tinggi peserta didik pada siklus I pada proses pembelajaran menunjukan ketuntasan sebesar 79% dan hasil tes kemampuan berpikir tingkat tinggi menunjukkan ketuntasan 26%. Sedangkan data observasi siklus dua pelaksanaan tahapan pembelajaran sosiologi dengan penerapan strategi REACT terlaksana (100%) dari 35 indikator. Kemudian meningkat pada siklus dua pada tahapan pembelajaran dengan ketuntasan mencapai 82% dan hasil tes kemampuan berpikir kritis menunjukkan ketuntasan 82%. Berdasarkan penelitian ini, maka dapat dinyatakan bahwa penerapan strategi pembelajaran REACT dapat menumbuhkan kreahlian berpikir kritis peserta didik kelas XI IPS 1 di SMA Negeri 1 Lingsar dalam pembelajaran sosiologi.
Construcción de una Celda de Combustible de Óxido Sólido para la Producción de Electricidad, Mediante el Uso y Optimización de la Perovskita La1-xSrx MnO3 (x = 0.2, 0.4) como Material Constituyente del Electrodo de Oxígeno.
Authors:   , Ramón Guillermo Cobo Rendón
Published: May 2023

La perovskita La1-xSrxMnO3 (x = 0.2, 0.4) (LSM) como material de electrodo de oxígeno para las celdas de combustible de óxido sólido (SOFC) se sintetizó por el método de combustión rápida en solución y se evaluaron sus características estructurales, morfológicas, mecánicas, eléctricas y ópticas mediante las herramientas de caracterización correspondientes. Los resultados de DRX mostraron la coexistencia de los polimorfos romboédricos R-3c y Pm-3m para la fase perovskita, corroboradas por imágenes HR-TEM, mostrando que el método de combustión rápida no permitió la formación pura de la fase La1-xSrxMnO3 (x = 0.2, 0.4) para las temperaturas de calcinación inferiores a 1400 y 1500°C respectivamente, debido a la rapidez de la síntesis de combustión 500°C durante 5 min. Se observó que el tamaño medio de los granos aumentaba con el tiempo de calcinación. El análisis EDS mostró una mejor concordancia de la estequiometría con la composición teórica. La porosidad aparente disminuyó con el aumento de la temperatura y el tiempo de calcinación debido a la coalescencia de los poros de sinterización. La dureza mejoró con el aumento del tiempo y la temperatura de calcinación y alcanzó un valor máximo de 5.7 GPa que coincidía simplemente con la densidad aparente. Se observó una tendencia similar en los estudios de resistividad en función de la temperatura y todas las muestras presentaron una resistividad baja de ~1.2 Ω-cm en el rango de temperaturas de 600-700°C. Para la muestra La0.6Sr0.4MnO3 la brecha de banda calculados oscilan entre 3.71 y 3.95 eV, lo que demuestra que el compuesto también puede ser un candidato adecuado para el desarrollo de dispositivos optoelectrónicos de alta frecuencia. A partir de estos fue construido una SOFC con diseño planar soportado sobre electrolito mediante la técnica de Screen Printing, tomando como electrolito el LSGM (La0.8Sr0.2Ga0.8Mg0.2O3) y electrodo de combustible LSCM (La0.75Sr0.25Cr0.5Mn0.5O3). La celda fue evaluada a 600 y 700 °C con 100 ml.min-1 de H2. La curva IV indicaba que el OCV aumentaba ligeramente al aumentar la temperatura, mientras que en circuito cerrado se obtenía una mayor potencia a temperaturas más elevadas. La potencia máxima alcanzada fue de 4.3 mW.cm-2 a 700°C, que correspondía al intervalo más bajo señalado en la bibliografía para este tipo de celdas de combustible. Los posibles factores que afectan al rendimiento son las perdidas por polarización debido al grosor de las capas de electrodos depositadas y la existencia de micro fisuras en el electrodo de combustible LSCM.
Simulação de trânsitos intraurbanos a partir da modelagem baseada em agentes: inferências para o planejamento urbano sustentável da cidade de Uberlândia, Minas Gerais, Brasil
Authors: Ferreira Raphaela , Dias Passos Karen Santini , de Araujo André Luís
Published: May 2023

Os caóticos processos de urbanização no Brasil acarretaram em inúmeros problemas no espaço urbano atual, como o espraiamento das cidades. A partir desta problemática, emerge a necessidade de se aperfeiçoar métodos de planejamento urbano capazes de garantir o desenvolvimento sustentável. Nesse sentido, entendendo que uma possível solução seja a densificação urbana, o presente trabalho com recorte no bairro Santa Maria em Uberlândia-MG, Brasil, simula com base em agentes a repercussão desta densificação, mais especificamente seus impactos diretos no trânsito local. Os resultados obtidos expressam que a infraestrutura urbana atual não seria capaz de comportar tal crescimento populacional, ocasionando novos problemas como conurbação e sobrecarregamento dos serviços. Portanto, apesar de assertivo, o adensamento deverá ocorrer em etapas e com distribuição uniforme pela cidade, garantindo que nenhuma região sobrecarregue outra para compensar.
Review on fluid-structure interaction problem modeling and recent developments
Authors: Ghazwan Alwan  , Aws Anaz  , Saif Sabah Irhayyim
Published: May 2023

The fluid-structure interaction (FSI) problem plays significant roles in engineering simulations and design. This problem considers the interaction between the fluid domain and structural domain with one-way or two-way data transfer. There are several algorithms to solve the problem, mainly numerical duo to the complexity and nonlinearly. The numerical schemes focus on the modeling method of the coupling interface. However, there are several algorithms that merge the interface in the equations and deal with the domains as a unified set of equations. Future development could include artificial intelligence modeling and the inclusion of more physical domains into the systems.
Dichrostachys cinerea (L.) Wight and Arn. (Fabaceae), a plant used in the traditional treatment of lymphatic filariasis in Côte d'Ivoire: Ethnopharmacological characteristics
Authors: Kouadio Bene  , Yomeh Cynthia Viviane Yapo  , Yao Kanga
Published: May 2023

Dichrostachys cinerea (L.) Wight & Arn. (Fabaceae) is a plant used in the traditional treatment of lymphatic filariasis. It was revealed following a recent ethnomedicinal survey. The present study aims to highlight the distinctive ethnopharmacological characteristics of Dichrostachys cinerea. The aim was to identify some groups of chemical compounds by thin layer chromatography, to assay some minerals and finally to characterise the specific anatomical and micrographic features of the plant. Terpenes and sterols, saponosides, flavonoids and tannins are the main phytocompounds revealed. Magnesium with 110.4 mg/100 g dry matter is the most abundant mineral. Anatomical sections revealed from the periphery to the interior of the organs, epidermis, collenchyma, cortical parenchyma, sclerenchyma, liber or phloem, the wood or xylem and the medullary parenchyma. In the plant powder, it was observed starch grains and calcium oxalate crystals. These results add to the data on Dichrostachys cinerea, a taxon much used in traditional Ivorian medicine for the treatment of lymphatic filariasis.
Recycling floral waste from temple using different techniques of eco-printing on cotton fabric
Authors: Meena Batham  , Sonali Mandhary
Published: May 2023

Today’s generation is becoming more environmentally conscious and shifting towards sustainable fashion. Unfortunately, synthetic dye is being dominantly used as they produce bright color and are cheap but are hazardous to health and as compared synthetic dye natural dye are chemical free, biodegradable and eco-friendly. Role of natural dye has been increased as preservation of traditional heritage is also one of the important sustainable development goals to which every country is trying to abide. Natural dyes are considered for their endurance and soft lustrous coloring. This research work focused on the extraction of natural dye by recycling floral waste from temples by using different techniques of Eco-printing on cotton fabric. Marigold and rose flowers were commonly used in India for worship. Pre-mordanting method was used for dyeing purposes, in which fabric was first mordant then used for printing. Commercially available tea powder (5gram) was used as Natural source of mordant. Further samples were tested on the basis of wash fastness and rub fastness properties. It was found that samples exhibit good wash and rub fastness.
Soil erosion hazard assessment using the RUSLE model for the Taung Watershed of Ramotswa Agricultural District in Botswana
Authors: Motshereganyi Sylvester Moesi  , Benedict Kayombo  , Rejoice Tsheko  , Emmanuel Setlhabi
Published: May 2023

The Revised Universal Soil Loss Equation (RUSLE) model integrated with Remote Sensing (RS) and Geographical Information Systems (GIS) was positively validated to spatially assess soil erosion risk in the Taung Watershed of Ramotswa Agricultural District during the period 2000 – 2020. The estimated annual soil erosion averaged 12.04 and 12.74 t/ha/year in 2000 and 2020, respectively. The Land Use/Land Cover (LULC) and soil type were found to be key determinants of high soil erosion hazard when using RUSLE. The soil erosion assessment tools enabled prioritization of high erosion prone areas in the study area for soil conservation planning and watershed management.
A rare case of Cushing syndrome ectopic-ACTH: A case report
Authors: Hassan Aden Neima  , S.Bammou  , S RAFI  , G El MGHARI  , N El ANSARI
Published: May 2023

Malignant tumors, nevertheless, have been associated with extremely high circulating ACTH and cortisol levels, and short duration of symptoms of Cushing syndrome (CS) besides atypical clinical phenotype, when compared with pituitary-dependent Cushing. A 33-year-old woman with a history of insulin-induced diabetes admitted to our department for suspicion of ACTH-dependent Cushing's syndrome held in front of : a Cushing's syndrome clinic, biological Cushing's syndrome, CLU : 2894ug/24h, minute braking : negative, cortisolemia 32.1ug/dl, ACTH : 232ng/l, CT scan of the adrenal glands in favor of moderate adrenal hyperplasia. MRI Pituitary without anomaly, strong negative braking. An Octreoscan objectified the presence of two thyroid nodules of hypodense generation moderately fixing the radiotracer, measuring respectively 1.9*1.2cm on the right and 1.5*1.1cm on the left. The focus intensely fixes the retrotracheal radiotracer and the right paravertebral retrotracer. Tumor markers are negative. The patient was operated on for anopathy : thyroid nodular dystrophy, reactive lymphadenitis, a review of the anopathy with iminohistochemistry is requested results in progress. The patient comes to our training 1 month post-operative, the patient reports a regular cycle return, the clinical examination shows a disappearance of purple stretch marks and bruises. Control octreoscan shows the absence of signs in favor of a neuroendocrine tumor at the pleuro-pulmonary, digestive or thyroid level. The nodule resected to objective the presence of anti-ACTH antibodies in immunohistochemistry. . Identification of the source of ACTH can be challenging, as sometimes the primary lesion is not identified even after prolonged and repeated follow-up.
Office information technologies and performance of Tertiary institutions in Southeast Nigeria
Authors: Anikeze Nnaemeka Hillary  , Abonyi Jonas Uchenna  , Okafor Ifeoma Cordelia
Published: May 2023

The study examined office information technologies and performance of Tertiary institutions in Southeast Nigeria. Specifically, the study sought to: investigate the influence of printer on employee job performance of tertiary institutions and ascertain the influence of photocopy machine on quality job delivery of tertiary institutions. Research design was descriptive survey research. Sample size of 378 respondents were drawn from 5,503 academic staff of three selected tertiary institutions in Southeast Nigeria namely University of Nigeria Nsukka, Nnamdi Azikiwe University Awka, Michael Okpara University of Agriculture Umudike and Ebonyi State University Abakiliki. The hypotheses were tested with regression analysis comprising student-t statistics. The empirical results show printer has significant influence on employee job performance of tertiary institutions in Southeast in Nigeria (t-statistics (9.292) > P-value (0.000) and photocopy machine has significant influence on quality job delivery of tertiary institutions in Southeast in Nigeria (t-statistics (6.312) > P-value (0.000). The study recommended that management of tertiary institutions in Nigeria should adopt the idea of using up-to-date information technology devices/tools so as avoid obsolescence so as to improve the service delivery.
SPBCSEV: Solar Power Based Charging Station for Electric Vehicles
Authors: Sunilkumar M. Hattaraki  , Achyut S Yaragal  , Rani U.Rotti  , Pavitra A.Hiremath
Published: May 2023

Electric vehicles, which are in high demand these days, emit no talipipe emissions, significantly reducing smog and greenhouse gas emissions. Electric vehicles use electricity to recharge their batteries rather than fossil fuels such as petrol and diesel. Electric vehicles are more efficient, and when combined with the cost of electricity, charging an electric vehicle is less expensive than filling up with petrol or diesel. With the growing demand for electric vehicles, there is a greater need for dependable and long-term charging infrastructure or systems. The purpose of this paper is to provide a sustainable and convenient charging solution for electric vehicles by utilizing renewable energy sources such as solar power. Furthermore, an electric vehicle charging station is created using an Arduino microcontroller, wireless charging coil modules, a solar panel, and an ESP8266 Wi-Fi module.
RP UFLC method for estimation of valsartan chemometricaly
Authors: SREEJANARDHANAN.V  , SHINE SUDEV
Published: May 2023

A simple, sensitive, rapid, precise and economical reverse phase HPLC method has been developed for the estimation of valsartan from pharmaceutical dosage forms. The method was carried out using Chromatographic conditions were established by employing a C18 analytical phenomenal (Kinetex) column (5micron -C18, 250x4.6mm) with a mobile phase of phosphate buffer (PH 3.5) and acetonitrile in a 60:40 ratio. The sample was injected at a volume of 20 microliters, and the mobile phase was degassed using a Sonica ultrasonic sonicator before being pumped into the HPLC system. The flow rate was set at 1 ml per minute, and the wave length 273 nm was chosen for detection. The column temperature was kept at 25oC respectively. The developed method was validated in terms of accuracy, precision, linearity, limit of detection, limit of quantitation and solution stability. The proposed method can be used for the estimation of these drugs in dosage forms.
Pengaruh Realisasi Pajak Kendaraan Bermotor (PKB) Dan Bea Balik Nama Kendaraan Bermotor (BBN-KB) Terhadap Pendapatan Asli Daerah Kabupaten Bangka
Authors: Sudarcun Sudarcun , Fikri Zakiyudin , Marlina Marlina
Published: May 2023

This study aims to determine the effect of the Realization of Motorized Vehicle Tax (PKB) and Motorized Vehicle Ownership Fee (BBN-KB) on Bangka Regency Regional Original Income. The research method used is quantitative research with an associative approach. The data used are primary data obtained from data on the realization of Motor Vehicle Taxes and Transfer Fees for Motorized Vehicles and the Realization of Local Own Revenue in Bangka Regency. The data analysis technique uses multiple regression with hypothesis testing using the t test and determination test. The results showed that the variable X1 (motor vehicle tax) obtained a significance value of 0.002, less than 0.05. it can be concluded that the variable X1 (Motor Vehicle Tax) has a positive and significant effect on Y (Local Original Income). Likewise, the X2 variable (Motor Vehicle Transfer Fee) obtains a significance value or Prob of 0.000 less than <0.05 (5%), the X2 variable (Motor Vehicle Transfer Fee) has a positive and significant effect on Y (Regional Original Income) ). Based on the results of the F test, it shows that the effect of X1 and X2 simultaneously on Y is 0.000, less than <0.05 and the calculated F value of 330,749 is greater than F table 5.75. this means that there is an effect of X1 and X2 simultaneously (simultaneously) on Y (Regional Own Revenue. The test results terminate in the R-squared value of 0.994 (99.4%) which means that the variables X1 (Motor Vehicle Tax) and X2 (motorized vehicle transfer fee) affect the Y variable (local original income) by 99.4%, the remaining 1.6% is influenced by other variables not included in the model.The conclusion is that the realization of motorized vehicle taxes and transfer of title fees has a significant effect on regional original income in Bangka Regency.
Politik Lokal: Komoditi Lokal dan Globalisasi ( Lumbung Ikan Nasional Sebagai Strategi Lompatan Glokalisasi di Maluku
Authors: Sigmarlatu Hendriyani
Published: May 2023

Abstract :

Penulisan ini akan mendiskusikan proses komoditas lokal sebagai lompatan skala dengan menyoroti lumbung ikan nasional Maluku sebagai strategi lompatan glokalisasi. Penulisan ini akan ada pada rujukan konseptual dan teori globalisasi atau glokalisasi. Jaringan teritorial dan penskalaan ulang yang ditulis dari Erik Swyngedouw. Penulisan ini menggunakan strategi pembahasan yang dibagi menjadi beberapa bagian pertama, membahas globalisasi dan dinamikanya kedua, memahami glokalisasi dan adaptasinya ketiga, membahas dinamika lompatan skala keempat, membahas strategi lumbung ikan nasional sebagai proses adaptasi skala kenakalan di Maluku. Penulisan ini hendak berangkat dari pemikiran Erik Swyngedouw di mana komunitas lokal dikelola menjadi nilai pasar global, sehingga menarik dikontekskan dengan Lumbung Ikan Nasional yang ada di Maluku

Kaca Kunci : LIN Maluku, Erik Swyngedouw, Komunitas Lokal, Globalisasi.
Memórias na velhice e narrativas de si a partir de objetos biográficos
Authors: NOGUEIRA Leila Mara Oliveira , GRANADO Laura Carmilo , MARQUES Bruna Gabriela , SALLES Rodrigo Jorge
Published: May 2023

O objetivo deste estudo foi analisar o papel dos objetos biográficos na velhice, tendo como campo teórico-metodológico o referencial psicanalítico sobre memória, velhice e narrativas de si. Os objetos biográficos são objetos pessoais que acompanham o idoso ao longo de sua trajetória de vida, possuindo um importante valor afetivo e pessoal. Estes objetos configuram-se como testemunhas de experiências subjetivas por acompanharem os indivíduos no processo de constituição de memórias, histórias e identidades individuais e coletivas. A relação entre indivíduo e o objeto biográfico faz-se importante para o envelhecimento, pois permite conectar o idoso com a sua própria história em um momento da vida marcado por diferentes alterações físicas, psíquicas e sociais. A presente investigação caracteriza-se como uma pesquisa de campo de natureza qualitativa. Participaram deste estudo seis idosos, três homens e três mulheres, com idade superior a 60 anos, que apresentaram um ou mais objetos biográficos que fazem parte da sua história de vida. Foram utilizados como instrumentos um questionário sociodemográfico e uma entrevista semiestruturada. Os dados foram avaliados através da técnica de análise de conteúdo proposta por Bardin (2016), adotando as seguintes etapas: (1) préexploração do material; (2) seleção de unidades temáticas relacionadas com o objetivo de analisar a relação entre os idosos, os objetos biográficos e suas memórias; (3) a construção de quatro categorias temáticas: objetos que compõem memórias; os objetos que marcam um tempo nas memórias; os objetos que integram memórias, e os objetos que perpetuam histórias. Os resultados da pesquisa evidenciam que os objetos biográficos têm a importante função de serem mediadores do tempo no resgate e perpetuação das reminiscências. Observou-se que a partir do narrar, o idoso pode integrar o passado com o presente, bem como o desejo de perpetuar histórias permeadas de saberes para gerações futuras. Este movimento permitiu a construção de narrativas que fortaleceram suas memórias e solidificaram as suas identidades pela integração de sua história. Destaca-se ainda que o processo de compor memórias possibilita ao idoso o reconhecimento de sua trajetória de vida, fato que o permite se localizar como sujeito apesar das diferentes marcas atribuídas pelo tempo, tais como mudanças físicas, sociais e vinculares presentes na velhice.
[Recebido em: 29 jul. 2021 – Aceito em: 30 out. 2021]
Carbono e as memórias dos outros
Authors: SILVA Breno Luiz Thadeu
Published: May 2023

O livro Carbono foi feito a partir de caminhadas, observações nas ruas, álbuns de família e conversas com moradores do São Benedito. Ele é uma das resultantes do projeto Espaço da Memória, que atua desde 2017, produzindo narrativas dos moradores do São Benedito, com ênfase nas constituições desse território do município de Santa Luzia na divisa com Belo Horizonte. Frequentando os arquivos digitais do Espaço da Memória é fácil perceber que muitas narrativas se cruzam, evidenciando pontos em comum. Tão comuns que poderiam ser sintetizados nas dificuldades de implantação das periferias metropolitanas brasileiras, com as questões de carências de infraestrutura e de acesso precário à moradia. Associando os “documentos” dispersos pelo São Benedito com os sistematizados nos arquivos do Espaço da Memória, a questão inicial, posta para a escrita do Carbono, foi a de como realizar uma narrativa coletiva a partir de fragmentos de memórias dos outros, de si mesmo e de “documentos” como achados imagéticos, conversas soltas, impressões dos espaços e referências dispersas no tempo. E o que resultaria dessas associações, com certeza seria uma memória dessusbtancializada, mas sem a mesma certeza, ela tenderia para algum sentido coletivo. Talvez, esse sentido coletivo saia da transmigração do trauma para figurar uma pós-memória num tempo-espaço mítico, como o entende Furio Jessi, enquanto locus da revolta. Carbono traz sete narrativas tangenciando o São Benedito. Esse artigo é um esboço reflexivo do próprio autor, desdobrando a trama da realização do livro. E, fundamentalmente, trata-se de uma digressão sobre o processo da escrita sobre as memórias dos outros.
[Recebido em: 29 jul. 2021 – Aceito em: 30 out. 2021]