bluuebunny/crossref_metadata_2025 huggingface dataset:
Resource-saving Technical Means for Soil Maintenance in the of Orchard and Vineyard Spacings
Authors:   Federal Scientific Center for Biological Plant Protection, Ponomarev A.V. , Kremneva O. Yu. ,   Federal Scientific Center for Biological Plant Protection, Danilov R.Yu. ,   Federal Scientific Center for Biological Plant Protection
Published: September 2021

The results of testing a resource-saving technical means for soil maintenance in the orchard and vineyard spacings are presented. The tests have performed according to two options for completing the chisel working bodies, that is to say, fitted with a chisel and sweeps, and fitted with a chisel without sweeps, on two backgrounds in order to determine the agro-engineering and energy indicators of the technical means.
Development Trends of Current Agricultural Tractors of Traction Class 3
Authors:   VIM, Starostin I.A. , Davydova S.A. ,   VIM, Eshchin A.V. ,   VIM, Goltyapin V. Ya. ,   Rosinformagrotekh
Published: September 2021

Specifications of current agricultural tractors of traction class 3 are analyzed, their distinctive features and main development trends are identified.
Investigation of the disinfecting properties of low-frequency electromagnetic oscillations
Authors:   Donskoy Agrarian Scientific Center, Pakhomov A.I. , Maksimenko V.A. ,   Donskoy Agrarian Scientific Center, Bukhantsov K.N. ,   Donskoy Agrarian Scientific Center, Vatutina N.P. ,   Donskoy Agrarian Scientific Center
Published: September 2021

The drawbacks of the existing methods of disinfection of grain and seeds are shown, a conclusion is made about the absence of a highly effective “green” method, which may be based on low frequency electromagnetic oscillations (up to 1 kHz), which have an inhibitory me chanism. The possibility of deep disinfection and an increase in laboratory germination of seed satcertain low frequencies has been investigated; thanks to their directional (resonant) action, energy savings and other advantages are achieved.
Enhancement of dissolution profile of poorly aqueous soluble atorvastatin calcium by binary and ternary solid dispersion techniques
Authors: Sarkar MR , Hossin A , Al Hossain ASMM , Sikdar KMYK , Raihan SZ , Hossain MH
Published: September 2021

Atorvastatin calcium (ATV) is an HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase inhibitor commonly known as a cholesterol-lowering agent. As a poorly water-soluble drug its absolute bioavailability is very low. To increase the water solubility as well as oral bioavailability, different hydrophilic carriers were used in different ratios (1:0.5, 1:1 and 1:2) to prepare reproducible binary and ternary solid dispersion formulations of ATV by simple physical mixing (PM) and fusion or melting technique. In vitro dissolution studies results revealed that in all cases, the cumulative percent drug release from ATV ternary SD formulations were greater than binary formulations, some marketed products and pure ATV powder. The order of the carriers in enhancing the drug release was found as kollidon 90F > pregelatinized starch > lutrol> kollidon 12F (99.1%, 98.8%, 96% and 95% respectively) for ternary SD formulations whereas pure ATV powder and marketed products showed cumulative percentage release 70.8%, 68.9% (B1) and 73.1% (B2), respectively. The best-out performed ternary SD formulation ATV:Kollidon 90 F (1:2) were further characterized using FT-IR and SEM. SEM analyses indicated conversion of crystal drug to amorphous form and FT-IR data suggested that little or no interaction between the drug and polymer.
Bangladesh J. Sci. Ind. Res.56(3), 165-176, 2021
Flowering attributes of Henckelia Royal Queen influenced by pinching and Paclobutrazol application
Authors: Wickramasinghe1 NPCH , Seran TH , Senarathne MMDJ
Published: September 2021

An experiment was carried out to determine the effect of pinching practice and different concentrations of Paclobutrazol (PBZ) on the flowering of Henckelia Royal Queen plants.Completely randomized design with eight treatment combinations of pinching or non-pinching and different concentrations of Paclobutrazol (0, 15, 30and 60 ppm) soil drenchwas usedwith eight replicates for each treatment. Pinching was practiced twice at two weeks intervals. Flowering parameters viz. number of flower buds, days taken to flowering, number of flowers, pedicel length, corolla length and corolla width were measured at two weeks intervals from 9thweek after the treatment application. Results disclosed that plants showed better flowering performances (P<0.05) with increasing concentrations of PBZ, but degree of leaf deformation was increased. Therefore, the application of 15 ppm PBZ with pinching showed better to obtain dwarf Henckelia Royal Queen plants with improved flowering quality as commercial potted plants.
Bangladesh J. Sci. Ind. Res.56(3), 177-184, 2021
Acute Small Gut Obstruction as an Atypical Presentation of Acute Appendicitis without Rupture or Perforation of the Appendix
Authors: Moniruddin ABM , Chowdhury Salma , Hasan Tanvirul , Mahmudul Hasan Kazi Muhammad , RounakJahan - , Hossain Kabir Ashfaque
Published: September 2021

Acute appendicitis is a very common surgical emergency. It has got diverse presentations and various complications. Here, we report case history of a young male patient with a 2- year history of recurrent abdominal pain, who presented to our center with a 4-day history of increasing abdominal pain, constipation and vomiting. Clinical and radiological evaluation revealed it as a case of acute intestinal obstruction preoperatively. Per-operative findings suggested acute appendicitis without perforation, small gut obstruction by adhesions, appendicular lump or internal herniation. Appendicectomy was done along with other necessary procedures. His post-operative period was uneventful. This case is reported here to highlight that acute appendicitis may present with atypical features like acute small gut obstruction.
J Bangladesh Coll Phys Surg 2021; 39: 261-265
Penerapan Strategi Pembelajaran Flipped Classroom Sebagai Implementasi dari Blended Learning pada Pembelajaran di Masa Pandemi Covid-19 dI MI NU Miftahul Falah Undaan Tengah
Authors: Elya Umi Hanik  , Dita Ramadhani Annisa
Published: September 2021

This study aims to determine the process of implementing learning strategies with flipped classrooms as the implementation of blended learning in learning during the Covid-19 pandemic at MI NU Miftahul Falah Undaan Tengah. The research method used is descriptive qualitative method by conducting interviews with class teachers. The learning process is carried out by combining online and offline learning with 50% online and 50% offline presentations. Students who do offline learning are divided into 2 stages, where 50% of the students leave on the first day, and the other 50% on the second day and so on. With data collection techniques in the form of interviews and documentation, the results of the study indicated that the learning carried out with the flipped classroom blended learning strategy had several advantages and obstacles.

[Penelitian ini bertujuan untuk mengetahui proses penerapan strategi pembelajaran dengan flipped classroom sebagai implementasi dari blended learning pada pembelajaran di masa pandemi covid-19 di MI NU Miftahul Falah Undaan Tengah. Metode penelitian yang digunakan adalah metode kualitatif deskriptif dengan melakukan wawancara kepada guru kelas. Proses pembelajaran dilakukan dengan memadukan pembelajaran secara daring dan luring dengan presentasi 50% secara daring dan 50% secara luring. Peserta didik yang melakukan pembelajaran secara luring dibagi menjadi 2 tahapan, dimana 50% jumlah peserta didik berangkat pada hari pertama, dan 50% yang lain pada hari kedua dan seterusnya. Dengan teknik pengumpulan data berupa wawancara dan dokumentasi, hasil penelitian menunjukkan bahwa pembelajaran yang dilakukan dengan strategi flipped classroom blended learning ini terdapat beberapa keunggulan dan hambatan]
Manajemen Pendidikan Karakter pada Kegiatan Intrakurikuler, Kokurikuler dan Ekstrakurikuler di MI Pembangunan UIN Jakarta
Authors: Muslim Bukhori
Published: September 2021

Character education is one part of national development that is prioritized by the current government. In character education, every school/madrasah must integrate character values through activities, such as intra-curricular, co-curricular and extra-curricular activities. However, the fact is that the character education implemented by schools/madrasas has not been implemented properly. One of the causes is the implementation of management functions in schools/madrasa that are less than optimal. The purpose of this study was to analyze and describe the implementation of character education management in intra-curricular, co-curricular and extra-curricular activities at MI Pembangunan UIN Jakarta. This research uses a qualitative approach with a descriptive method. Data collection techniques through observation, interviews, and documentation. The data analysis technique uses the Miles and Huberman model, namely data reduction, data presentation, and drawing conclusions. The results of this study are; Character education management refers to the management function, namely planning, organizing, implementing and supervising the 5 main values of education, namely religious, nationalist, independent, mutual cooperation and integrity in every intracurricular, cocurricular, and extracurricular activity.

[Pendidikan karakter menjadi salah satu bagian dari pembangunan nasional yang diprioritaskan pemerintah saat ini. Dalam pendidikan karakter setiap sekolah/madrasah harus mengintegrasikan nilai-nilai karakter melalui kegiatan, seperti intrakurikuler, kokurikuler dan ekstrakurikuler. Namun faktanya pendidikan karakter yang diterapkan oleh sekolah/madrasah belum terlaksana dengan baik. Salah satu penyebabnya adalah penerepan fungsi manajemen di sekolah/madrasah yang kurang optimal. Tujuan penelitian ini untuk menganalisis dan mendeskripsikan pelaksanaan manajemen pendidikan karakter pada kegiatan intrakurikuler, kokurikuler dan ekstrakurikuler, di MI Pembangunan UIN Jakarta. Penelititan ini menggunakan pendekatan kualitatif dengan metode deskriptif. Teknik pengumpulan data melalui observasi, wawancara, dan dokumentasi. Teknik analisis data menggunakan model Miles dan Huberman, yaitu reduksi data, penyajian data, serta penarikan kesimpulan. Hasil penelitian ini adalah; manajemen pendidikan karakter mengacu pada fungsi manajmen yaitu perencanaan, pengorganisasian, pelaksanaan dan pengawasan yang terintegrasi pada 5 nilai utama pendidikan, yaitu religius, nasionalis, mandiri, gotong royong dan integritas di setiap kegiatan intrakurikuler, kokurikuler, dan ekstrakurikuler]
ESSENTIAL FATTY ACIDS IN DIET AND THEIR ROLE IN IMPROVING PHYSICAL PERFORMANCE OF SKI RACERS
Authors: Lyudinina A. Yu. , Garnov I. O. , Bojko R. Rafailovich
Published: September 2021

Introduction: Associations between nutrition and physical performance among elite sportsmen have been extensively studied, although not all nutrients have been covered by these studies. For example, there is still lack of information on the levels of consumption of essential fatty acids (FAs) and their influence on the physical performance among high-performing ski racers. Aim: To study associations between consumption of essential fatty acids and indicators of physical performance Russian ski-racers. Methods: Thirty seven male members of the Komu republic team the Russian national team in cross-country ski aged 17- 33 years took part in this study. To assess physical performance, athletes underwent a test VO2 max, on the Oxycon-Pro ergospirometric system in the "breath-by-breath" mode. Indicators of oxygen consumption (VO2), oxygen utilization ratio, VO2 max, heart rate (HR), blood pressure (BP), anaerobic threshold (AnT), Watt/pulse were estimated. Consumption of different classes of FAs was assessed using the on-line service "Fatty acids in food items". Results: High variability in the consumption of difference classes of Fas was observed. Most ski racers reporten and higher consumption of n-6 linoleic acid and saturated fats compared to the recommended values. At the same time, consumption of n-3 eicosapentaenoic and docosahexaenoic acids was lower than recommended. Singificant correlations were observed between essential а-linolenic acid cnosumption and VO2 max and watt/pulse AnT in the studied sample. Conclusion: Our results suggest an association between the indicator of the efficiency of autonomic support for muscle work -the watt/pulse AnT and insufficient consumption of а-linolenic acid. The results of the study can be applied to optimize the diet and increase the functional reserves and physical performance in athletes.
Detecting Land Use Change in The Jordan University District During the Period of (1985-2019) Using GIS and Remote Sensing
Authors: Salameh Lina Ahmad Ali Bany , Al-Sagarat Associated Prof. OMAR Farhan
Published: September 2021

This study aimed to evaluate the changes in usage patterns of lands in Jordan University district for the period (1985-2019), demonstrate the impact of natural factors, humans, in the use of change, and identify the trend of urbanization. To achieve the study objectives, the analytical method, descriptive method, and historical method were used, it also relied on Landsat satellite images, images by Google Earth Pro, and metadata serving the subject of study.
The study findings demonstrated the changing in the land use due to increasing urban lands by 12.5% during the study period, decreasing agricultural lands by –40%, decreasing rangeland by -49%, decreasing barren lands by -42.6%, and decreasing forest area by -50.5%. The study used logistic regression, to predict the usage area of urban and agriculture aspects, and it is demonstrated increasing the urban land by (110823donums) of the district's area, and decreasing the agriculture lands by 2029.
Development of Community Tourism Services in Ha Giang Province
Authors: Thuy Nguyen Thu , Van Anh Tran Thi , Nguyen Nguyen Thao
Published: September 2021

Ha, Giang has become an increasingly attractive destination for both domestic and foreign tourists, thanks to its unique natural and social conditions. In particular, community-based tourism is the highlight of the province's tourism when there is a connection of indigenous people to develop tourism. In order for community-based tourism to really develop, tourism services need to be focused on improving quality and diversifying in order to make a difference and retain visitors. The article finds that Ha Giang's tourism products are quite rich but have not yet created specific features and are copied, so they have not increased the spending level of tourists coming to Ha Giang's community-based tourism. Therefore, the group suggested a number of solutions such as: Organizing to upgrade and expand community-based tourism activities, Strengthen and improve the effectiveness of state management of tourism, promote the participation of the local communities in tourism development…Hopefully, these changes will help improve the quality of tourism services and satisfy visitors to Ha Giang.
Determination of failure rate function on the basis оf the markovian process
Authors:   National Transport University, Bashkevych Iryna , Yevseichyk Yurii ,   National Transport University, Medvediev Kostiantyn ,   National Transport University, Yanchuk Leonid ,   National Transport University
Published: September 2021

The life cycle of a construction (or its element) is considered as markovian process with discrete states and continuous time. Five operational states have been accepted, in which the construction may be. The corresponding system of differential equations is obtained for the case of a homogeneous markovian process with a constant conversion rate (Kolmogorov system). The method of uncertain coefficients is applied to solve the system of equations in analytical form. The obtained solutions make it possible to determine the probability of finding the construction in a particular state as well as the most likely transition time from one operational state to another. Security function defined as the probability of not finding the construction in its last (inoperable) state and the failure rate function. The graphs of the probability of finding a construction in each of the five states, reliability and failure rate functions are presented and investigated. The obtained analytical dependences make it possible to determine the longevity and residual life of the work both individual elements and structures as a whole and optimize scheduling for ongoing maintenance work, significantly improve the performance of the structure, reduce the cost of repair work and extend the life of the structure.
The paradox and paradigm of educational, scientific and applied activities in conditions of uncertainty (part 1)
Authors:   National Transport University, Gameliak Igor , Vakarchuk Ihor ,   National Transport University, Ivanova Oleksandra ,   National Transport University
Published: September 2021

The article reveals the paradox and paradigm of educational, scientific and applied activities on the example of the Airports Department of the National Transport University during the specialists for the transport and road complex training in the field of «Airports, aerodrome constructions and structures» and «System analysis in transport infrastructure» in conditions of coronavirus pandemic uncertainty. The presented author's model is based on the principles of establishing the systematic competency approach implementation mechanism and innovative technologies of distance learning application, which was obtained in the process of domestic and foreign experience analysis under coronavirus pandemic uncertainty. The research object – educational, research and applied activities of the Airports Department, as a Laboratory of Systems Knowledge and Rational Infrastructure Solutions within the National Transport University, which is positioned as a Regional Educational and Research Logistics Center on the basis of outsourcing in distance learning and coronavirus pandemic uncertainty. The purpose of the work is to establish a mechanism for competency approach systematic implementation and innovative technologies application for the «teacher–student–employer» relationship, which allows to determine the most effective ways and means to achieve the ultimate goals of educational, scientific and applied activities in the coronavirus pandemic uncertainty. providing highly qualified personnel to the transport and road complex of the country. Research methods – system, conceptual, methodological and program approaches. Establishing of a mechanism for the model «teaching methods–learning outcomes–assessment» applying innovative technologies according to the competency algorithm «knowledge of theory–application skills–technology skills» to strengthening the relationship «teacher–student–employer», will bring the results of the educational process to employers requirements and provide the transport and road complex with highly qualified personnel. Further development of the study object – the introduction of educational, scientific and applied activities «Laboratory of Systems Knowledge and Rational Infrastructure Solutions» as part of the «Regional Educational and Scientific Logistics Center», will achieve the ultimate goals of providing transport complex by highly qualified personnel in terms of distance learning and coronavirus pandemic uncertainty.
Influence of road conditions on vehicles’ fuel consumption
Authors:   National Transport University, Dodukh Kateryna , Palchyk Anton ,   National Transport University
Published: September 2021

The article deals with the influence of road conditions on fuel consumption by vehicles when transporting goods and passengers, which depends on the speed of movement. The optimum fuel consumption corresponds to the optimum speed of movement which is distinctive for each type of car. Increase or decrease of the optimum speed leads to increased fuel consumption. Elevations reduce the speed and increase fuel consumption by up to 30%. Road conditions (width of roadway, condition of surface, presence of horizontal curves, longitudinal slopes, pedestrian crossings, settlements) cause a change in the speed of movement and consumption of fuel and lubricants. It is possible to take into account the road conditions by plotting the speed of movement along the route, the change in the speed occuring during the travel time and socio-economic indicators of the route. Based on this chart, fuel costs and route times are calculated. Since the cost of fuel is 50-52% of the cost of transportation of goods and passengers, the cost will be roughly 2 times higher. The cost of transportation of goods by trucks is characterized by the cost of transportation, and the transportation of passengers by the cost and time spent by passengers when traveling the route.
Proposals for improving of transport systemological terminology (part 4)
Authors:   National Transport University, Petrashevskyi Oleh , Popelish Ivan ,   National Transport University, Alieksieienko Oleksandr ,   National Transport University, Koritchuk Sergey ,   National Transport University, Artemchuk Yuliia ,   National Transport University
Published: September 2021

We continue to publish proposals for improving transport systems. This article defines the 4th part of a large topic on the creation and adjustment of terms and definitions required for communication processes of communication, primarily researchers in this field of subject activity "researcher of transport systems (theorist) - researcher of transport systems (practitioner)". The second aspect of verвal interaction is to establish a communication relationship between "man - computer", which is important in modern conditions.
The emergence of free intervals in the traffic flow depending on the intensity of movement and speed
Authors:   National Transport University, Sokolenko Tetiana , Palchyk Anatoliy ,   National Transport University
Published: September 2021

The movement of single and group cars in traffic flows was investigated during the work. These studies are used to calculate the vehicle delay time during maneuvers through crossings and adjacencies at the same level. On the basis of the data obtained, the technical and economic discussion of the cross-sectional or adjoining parameters under consideration can be made. In the course of the study, examination will be conducted on the influence of intensity, velocity and traffic flow on the distribution intervals between cars and a graph of this effect for different traffic intensities is to be constructed. On the basis of the provided charts, the dependence of the free interval, necessary for maneuvering, on the traffic flow intensity is described. Using this dependence, you can figure out the number of cars that can be transported continuously. Knowing the traffic flow, its intensity and the distribution of free intervals between cars and groups of vehicles, the lag time of cars that are waiting for the ability to maneuver as well as their quantity can be calculated with the help of the proposed method.
Risks assessment on business planning
Authors:   National Transport University, Kozarchuk Ihor
Published: September 2021

The article studies issues related to risks in entrepreneurial activity. The factors and reasons for its occurrence are analyzed. Methods for risk assessment are reviewed, among which special attention is paid to methods based on mathematical statistics and expert assessments. It is concluded that risk has a positive effect – it stimulates enterprises to improve the business planning system.
Functioning of the system of comprehensive analysis of the activity of the production enterprise
Authors:   National Transport University, Lykhostup Mykola , Gorban Irina ,   National Transport University
Published: September 2021

The article considers the basics of the system of complex analysis of the enterprise engaged in transport construction, which is proposed to be implemented in three stages. The idea of ​​allocating such stages determines the needs of the enterprise in obtaining decisions not only about the current shortcomings in its activities, but also about the positive directions of its development. At each stage of the analysis, it is proposed to use relatively simple, but effective and accessible to employees of the enterprise methods. The first, which is generally presented as a rapid analysis, uses relatively simple expert methods. At the second stage, when it comes to the analysis of current activities of the enterprise, it is recommended to use calculation and analytical methods, which are developed in official methods and recommendations. The third stage is the stage of conducting scientific and practical work and research, which are aimed at obtaining important decisions in the field of significant change and improvement of the enterprise. Each stage of the analysis of activity of the enterprise is shown in article by examples of the decision of its component problems.
Temperature oscillations influence in asphalt concrete layers on stress-deformed condition of road pavement
Authors:   National Transport University, Baran Serhii , Bilobrytska Olena ,   National Transport University, Hrynchak Ilona ,   National Transport University, Kutsman Oleksandr ,   National Transport University, Shevchuk Lyudmila ,   National Transport University
Published: September 2021

The durability of asphalt pavement depends on the stress-strain state of the pavement structure, which is significantly affected by temperature fluctuations. The calculation and analysis of the stress-strain state of typical pavement structures with asphalt concrete pavement for roads at different temperatures of their operation are performed. It is established that a significant role in predicting the strength and durability of asphalt pavement is played by temperatures that vary in annual and daily conditions. Tensile stresses in the coating occur not only at low temperatures during the spring waterlogging of soils, but also at other temperatures. Thus, with increasing temperature, the modulus of elasticity of asphalt concrete naturally decreases, which leads to a decrease in the value of horizontal normal tensile stresses of asphalt concrete layers during their bending during transport, but at the same time more significantly reduces the tensile strength of asphalt concrete.
Investigation of the thermally stressed state of shallow shells on a rigid base with a sliding contact layers using analytic solutions of equations оf elasticity theory
Authors:   National Transport University, Marchuk Alexander , Levkivskiy Sergii ,   National Transport University, Gavrilenko Elena ,   National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”
Published: September 2021

Modern calculations of layered plates and shells in a three-dimensional formulation are based on a technique where the distribution of the desired functions over the thickness of a structure is sought by the method of discrete orthogonalization. In this article, based on the approaches developed by the authors, the thermally stressed state of layered composite shallow shells with a rigidly fixed lower surface is analyzed. The distribution of the desired functions over the thickness of the structure is found based on the exact analytical solution of the system of differential equations. An approach to the study of the thermal stress state of shallow composite shells is considered, and an analytical model is constructed for calculating the thermal stress state of shallow shells on a rigid base with a sliding contact of the layers. Currently, this is a very urgent task when calculating the pavement of bridges. A feature of this approach is the assignment of the desired functions to the outer surfaces of the layers, which allows one to break the layer into sublayers, reducing the approximation error to almost zero. Using the model in question, an analysis of flat layered composite shells on a rigid base with a sliding contact of the layers under the influence of temperature loading was carried out. To build a spatial model, a load option is selected with temperature loads (according to the sine law) and boundary conditions (Navier), which lead to the distribution of the desired functions in terms of a plate with trigonometric harmonics of the Fourier series. A polynomial approximation of the desired functions by thickness is involved. Using the model in question, an analysis of flat layered composite shells on a rigid base with a sliding contact of the layers under the influence of temperature loading was carried out. The considered example showed that the proposed model provides sufficient accuracy in the calculations of layered shallow shells when considering each layer within one sublayer. The proposed approach can be used as a reference method for testing applied approaches in calculating various stress states of layered flat composite shells.
Investigation of the influence of surfaces between basic stations and satisfactory recognition on the accuracy of coordinating definitions
Authors:   National Transport University, Neizvestna Natalia , Khomiak Anna ,   National Transport University, Omelchuk Sibilla ,   National Transport University, Malko Marya ,   National Transport University
Published: September 2021

The distance between different base stations and the mobile receiver, as well as errors of coordinate definitions at different distances between the base station and the mobile receiver are investigated. For realization of the set tasks the following methods of research were applied: field measurements, mathematical modeling method and methods of mathematical statistics for the processing of experimental data. The degree of influence of distances between the base station and the satellite receiver on accuracy of coordinate definitions in RTK-mode is established.
Research of environmental risk factors in estimation of real estate
Authors:   National Transport University, Bondarenko Liudmyla , Kushnirova Oksana ,   National Transport University
Published: September 2021

The paper investigates environmental risk factors that determine the value of real estate assets and make valuation decisions. It is determined that the components of the environment are the object of the cumulative impact of environmental risk, and indirectly through them are real estate objects and people. Among all the environmental components, the most decisive is the atmosphere, as the harmful substances coming from the atmospheric air into the human body are absorbed most intensely. The main criterion for environmental risk assessment is the degree of influence of harmful substances on the health of the population. The systematization of environmental risk factors, which provides an analysis of the causes, sources and significance of negative material and physical impact in the study area with the separation of two qualitatively different types of environmental risk: direct and indirect. Both positive and negative environmental factors that affect the value of real estate are listed. It is proposed to determine environmental risk as part of a probabilistic approach to assess the deterioration of life due to the deterministic and stochastic effects of environmental pollution surrounding a real estate object. Dependencies for quantitative estimation of direct and indirect environmental risks are determined. Conceptual bases for objective consideration of negative environmental factors of material and physical nature in the developed territories have been developed.
The paradox and paradigm of educational, scientific and applied activities in conditions of uncertainty (part 2)
Authors:   National Transport University, Gameliak Igor , Vakarchuk Ihor ,   National Transport University, Ivanova Oleksandra ,   National Transport University
Published: September 2021

The article reveals the paradox and paradigm of educational, scientific and applied activities on the example of the Airports Department of the National Transport University during the specialists for the transport and road complex training in the field of «Airports, aerodrome constructions and structures» and «System analysis in transport infrastructure» in conditions of coronavirus pandemic uncertainty. The presented author's model is based on the principles of establishing the systematic competency approach implementation mechanism and innovative technologies of distance learning application, which was obtained in the process of domestic and foreign experience analysis under coronavirus pandemic uncertainty. The research object – educational, research and applied activities of the Airports Department, as a Laboratory of Systems Knowledge and Rational Infrastructure Solutions within the National Transport University, which is positioned as a Regional Educational and Research Logistics Center on the basis of outsourcing in distance learning and coronavirus pandemic uncertainty. The purpose of the work is to establish a mechanism for competency approach systematic implementation and innovative technologies application for the «teacher–student–employer» relationship, which allows to determine the most effective ways and means to achieve the ultimate goals of educational, scientific and applied activities in the coronavirus pandemic uncertainty. providing highly qualified personnel to the transport and road complex of the country. Research methods – system, conceptual, methodological and program approaches. Establishing of a mechanism for the model «teaching methods–learning outcomes–assessment» applying innovative technologies according to the competency algorithm «knowledge of theory–application skills–technology skills» to strengthening the relationship «teacher–student–employer», will bring the results of the educational process to employers requirements and provide the transport and road complex with highly qualified personnel. Further development of the study object – the introduction of educational, scientific and applied activities «Laboratory of Systems Knowledge and Rational Infrastructure Solutions» as part of the «Regional Educational and Scientific Logistics Center», will achieve the ultimate goals of providing transport complex by highly qualified personnel in terms of distance learning and coronavirus pandemic uncertainty.
EMOCIONES MOSTRADAS POR LOS ESTUDIANTES ANTE LA SITUACIÓN DEL COVID-19, ISFODOSU, RECINTO LUIS NAPOLEÓN NÚÑEZ MOLINA
Authors:   Instituto Superior de Formación Docente Salomé Ureña, Bennasar García Miguel Israel , Blanco Pérez Judit Del Carmen , Gómez Lora Jonathan De Jesús , Vargas Jean Carlos
Published: September 2021

La presente investigación se orientó a indagar las emociones mostradas por los estudiantes ante la situación del Covid-19, Instituto Superior de Formación Docente Salomé Ureña, Recinto Luis Napoleón Núñez Molina y su impacto en el estrés, ansiedad y depresión provocando la falta de interés en aprender, desfavoreciendo su proceso de enseñanza y aprendizaje. El Objetivo General consistió en crear estrategias que ayuden a controlar las emociones mostradas por los Estudiantes ante la situación de la pandemia. El itinerario metodológico utilizado fue el estudio de campo en su nivel descriptivo y como técnica de recolección de información el cuestionario tipo encuesta, que de acuerdo a su naturaleza da cuenta de la necesaria búsqueda de elementos y teorías, que tratan y exponen el tema, lo que sirvió de bases para el ulterior análisis, sobre la naturaleza de este asunto tan vital para la sociedad y la universidad. Dentro de los resultados se logró establecer y aplicar estrategias de juegos mentales para restablecer los niveles de concentración en los estudios de manera adecuada, a propósito de la pandemia. Dentro de las conclusiones: La realización de entrenamiento mental que se adecúe a la situación que se vive con el Covid-19, ha sido de utilidad, lo que ha permitido obtener un buen avance en el nivel académico de los estudiantes y el liberar el estrés que han tenido por la pandemia.
INTERVENCIÓN EDUCATIVA BASADA EN LA APLICACIÓN DE METODOLOGÍAS ACTIVAS EN EL APRENDIZAJE DE LA LECTOESCRITURA EN ESTUDIANTES DE EDUCACIÓN INICIAL.
Authors:   Universidad Nacional de Chimborazo, Alvear Ortiz Luis Fernando , Hernández Zumba Inés María ,   Universidad Nacional de Chimborazo, Chacaguasay Quishpe Betty Maribel ,   Unidad Educativa "Camilo Gallegos Toledo", Allauca Salguero Rosa Elizabeth ,   Universidad Nacional de Chimborazo, Bonilla Gavino Mario Fabian ,   Unidad Educativa "Camilo Gallegos Toledo"
Published: September 2021

El proceso educativo en edades tempranas de la vida se basa en la adquisición de habilidades y destrezas. La lectoescritura es considerada como la actividad educativa fundamental a cumplir durante el inicial 2. El objetivo del estudio fue implementar una intervención educativa, basada en la aplicación de metodologías activas, en el aprendizaje de la lectoescritura de estudiantes de inicial 2 de la unidad educativa Vygotsky. Para esto se realizó una investigación aplicada, con un diseño cuasi experimental en la que la población estuvo constituida por los 31 estudiantes, se aplicó una prueba diagnóstica (pretest) al comenzar la investigación y después de terminar de implementar la intervención educativa (postest). Se utilizó la prueba no paramétrica de McNemar para determinar el efecto causado por la intervención aplicada en el nivel de habilidades, destrezas y conocimientos relacionados con la lectura y la escritura. Los principales resultados muestran un promedio de edad de 4,75 años, con predominio de niños (61,29%). Predominaron durante el pretest niveles medios de conocimientos (51,61%), habilidades (51,61%) y destrezas (48,39%) en la lectura y niveles medios de conocimientos (45,16%), habilidades (48,39%) y destrezas (51,61%) en la escritura. Durante el postest aumentaron los porcientos de estudiantes con niveles altos de conocimientos habilidades y destrezas tanto en la lectura como en la escritura y disminuyeron los porcientos de estudiantes con niveles bajos. Se concluye que la intervención educativa aplicada provocó cambios positivos en los niveles de habilidades, destrezas y conocimientos de los estudiantes investigados.
USO DE LAS TIC COMO ESTRATEGIA EDUCATIVA EN BENEFICIO DEL APRENDIZAJE SIGNIFICATIVO
Authors:   Universidad Nacional de Chimborazo, Alvear Ortiz Luis Fernando , Torres Peñafiel Jhonny Santiago ,   Universidad Nacional de Chimborazo, Janeta Patiño Paco Fernando ,   Universidad Nacional de Chimborazo, Román Proaño Jimmy Vinicio ,   Universidad Nacional de Chimborazo
Published: September 2021

El uso de las Tecnologías de la Información y las Comunicaciones es considerado como recursos y herramientas tecnológicas cuya utilización en el sistema educativo aporta beneficios a pesar de que aun su implementación es insuficiente. La presente investigación tuvo como objetivo dar a conocer la importancia del uso de las TIC como estrategia educativa en beneficio del aprendizaje significativo. Para esto se realizó una investigación básica, no experimental, de corte transversal en 20 docentes universitarios de la carrera de Educación Inicial de la Facultad de Ciencias de la Educación Humanas y Tecnologías de la Universidad Nacional de Chimborazo; se aplicó una encuesta para obtener información relacionada con las características generales de los docentes y elementos relacionados con el uso de las Tecnologías de la Información y las Comunicaciones. Los principales resultados incluyen promedio de edad de 41,76 años, predominio de docentes masculinos (70,0%), entre 2 y 5 años de experiencia en docencia (55,0%) que utilizan diariamente el servicio de internet y que consideran que estas técnicas ayudan al aprendizaje significativo (85,0%). Se concluye que el uso de las TICs por parte de los docentes aun es irregular e insuficiente, a pesar de las claras ventajas que ofrece su utilización en la generación y consolidación del conocimiento en los estudiantes
LA POBREZA Y LA INCLUSIÓN PRODUCTIVA EN LA PROVINCIA DE TUNGURAHUA
Authors:   Universidad Técnica de Ambato, Barrera Erreyes Helder Marcell ,   Pontificia Universidad Católica del Ecuador, Cruz Lascano Mary Elizabeth ,   Universidad Técnica de Ambato, Valle Álvarez Alexandra Tatiana ,   Universidad Técnica de Ambato, Valencia Nuñez Edison Roberto ,   Universidad Técnica de Ambato
Published: September 2021

La pobreza por ingresos es sinónimo de carencia y privación, que limita a una persona para alcanzar un mínimo nivel de vida, y según estimaciones de nuevos estudios se prevé que llegará a 68 y 135 millones de personas para el 2030. A esto acompaña la pandemia del COVID-19 y según los pronósticos tendremos entre 703 y 729 millones. Los “nuevos pobres” probablemente vivirán en entornos urbanos superpoblados y trabajarán en sectores más afectados por el confinamiento, además trabajarán en servicios informales y manufactura pero menos personas se dedicarán a la agricultura. Tungurahua que es una provincia del Ecuador, que ocupa el tercer lugar en índices de pobreza, esto por la frágil situación del país y la falta de empleo, por eso se cree que es importante apoyar a la empresa privada y a los emprendimientos cuyo objetivo es promover el desarrollo de unidades productivas de pequeño y mediano porte, provenientes de la economía social y diversas figuras de trabajo asociado. Como parte de la reactivación económica en esta provincia y por sus características agrícolas y productivas se hará partícipes a todos los emprendedores, quienes tendrán asistencia técnica, capacitación, ayuda a la comercialización de productos, seguimiento y evaluación por parte de las entidades gubernamentales, para ello se empezará con un diagnóstico y se planteará una planificación de fortalecimiento económico.
ESTILOS DE VIDAS DE LOS ADULTOS MAYORES RESIDENTES EN PARROQUIAS RURALES DEL CANTON RIOBAMBA
Authors:   Escuela Superior Politécnica de Chimborazo, Yaulema Brito Lorena Patricia , Parreño Urquizo Ángel Floresmilo ,   Escuela Superior Politécnica de Chimborazo, Ríos Guarango Patricia Alejandra ,   Escuela Superior Politécnica de Chimborazo
Published: September 2021

Los estilos de vida son conceptualizados como las acciones que caracterizan las actividades diarias de una persona. Juegan un papel fundamental en la prevención o aparición de enfermedades; mantener estilos de vida saludables constituye una prioridad en los adultos mayores. El objetivo de esta investigación fue describir el comportamiento de los estilos de vida en adultos mayores residentes en parroquias rurales del cantón Riobamba, Chimborazo, Ecuador. Para esto se realizó una investigación descriptiva. El universo estuvo constituido por 730 adultos mayores. La muestra quedó conformada por 225 personas. A todos se les aplicó un cuestionario que permitió obtener la información necesaria. Los principales resultados incluyeron un promedio de edad de 67,44 años con predominio de féminas (60,44%). El 76,00% de los ancianos viven solos y el 79,11% presentó diagnóstico de enfermedad crónica. El 94,22% realizan actividades físicas menos de 2 veces por semana y el 92,44% consumía una alimentación inadecuada en el momento de realizar la investigación; el 79,11% acude a controles de salud menos de 2 veces al año. Se concluye que existe un elevado por ciento de adultos mayores con estilos de vida poco saludables caracterizado principalmente por elevada presencia de enfermedades crónicas, alimentación poco saludable y baja práctica de actividades físicas.
Tumor Microenvironment Responsive Pepper Mild Mottle Virus-Based Nanotubes for Targeted Delivery and Controlled Release of Paclitaxel
Authors: Peng Jiejun , Yin Yueyan , Liang Hongze , Lu Yuwen , Zheng Hongying , Wu Guanwei , Rao Shaofei , Chen Jianping , Yan Fei , Hu Jingbo
Published: September 2021

Plant virus nanoparticles (PVNPs) have been widely used for drug delivery, antibody development and medical imaging because of their good biodegradation and biocompatibility. Particles of pepper mild mottle virus (PMMoV) are elongated and may be useful as drug carriers because their shape favours long circulation, preferential distribution and increased cellular uptake. Moreover, its effective degradation in an acidic microenvironment enables a pH-responsive release of the encapsulated drug. In this study, genetic engineering techniques were used to form rod-shaped structures of nanoparticles (PMMoV) and folated-modified PMMoV nanotubes were prepared by polyethylene glycol (PEG) to provide targeted delivery of paclitaxel (PTX). FA@PMMoV@PTX nanotubes were designed to selectively target tumor cells and to release the encapsulated PTX in response to pH. Efficient cell uptake of FA@PMMoV@PTX nanotubes was observed when incubated with tumor cells, and FA@PMMoV@PTX nanotubes had superior cytotoxicity to free PTX, as reflected by cell survival and apoptosis. This system is a strong candidate for use in developing improved strategies for targeted treatment of tumors.
Quorum Sensing Inhibiting Activity of Cefoperazone and Its Metallic Derivatives on Pseudomonas aeruginosa
Authors: Naga Nourhan G. , El-Badan Dalia E. , Rateb Heba S. , Ghanem Khaled M. , Shaaban Mona I.
Published: September 2021

The last decade has witnessed a massive increase in the rate of mortalities caused by multidrug-resistant Pseudomonas aeruginosa. Therefore, developing new strategies to control virulence factors and pathogenicity has received much attention. One of these strategies is quorum sensing inhibition (QSI) which was developed to control Pseudomonas infection. This study aims to validate the effect of one of the most used β-lactam antibiotics; cefoperazone (CFP) and its metallic-derivatives on quorum sensing (QS) and virulence factors of P. aeruginosa. Assessment of quorum sensing inhibitory activity of CFP, cefoperazone Iron complex (CFPF) and cefoperazone Cobalt complex (CFPC) was performed by using reporter strain Chromobacterium violaceum ATCC 12472. Minimal inhibitory concentration (MIC) was carried out by the microbroth dilution method. The influence of sub-MICs (1/4 and 1/2 MICs) of CFP, CFPF and CFPC on virulence factors of P. aeruginosa was evaluated. Data was confirmed on the molecular level by RT-PCR. Also, molecular docking analysis was conducted to figure out the possible mechanisms of QSI. CFP, CFPF, and CFPC inhibited violacein pigment production of C. violaceum ATCC 12472. Sub-MICs of CFP (128- 256 μg/mL), and significantly low concentrations of CFPC (0.5- 16 μg/mL) and CFPF (0.5- 64 μg/mL) reduced the production of QS related virulence factors such as pyocyanin, protease, hemolysin and eliminated biofilm assembly by P. aeruginosa standard strains PAO1 and PA14, and P. aeruginosa clinical isolates Ps1, Ps2, and Ps3, without affecting bacterial viability. In addition, CFP, CFPF, and CFPC significantly reduced the expression of lasI and rhlI genes. The molecular docking analysis elucidated that the QS inhibitory effect was possibly caused by the interaction with QS receptors. Both CFPF and CFPC interacted strongly with LasI, LasR and PqsR receptors with a much high ICM scores compared to CFP that could be the cause of elimination of natural ligand binding. Therefore, CFPC and CFPF are potent inhibitors of quorum sensing signaling and virulence factors of P. aeruginosa.