bluuebunny/crossref_metadata_2025 huggingface dataset:
Seeking a More Ethical Future for Ethnobiology Publishing: A 40-Year Perspective from Journal of ethnobiology
Authors: Lepofsky Dana , Heckelsmiller Cynthiann , Fernández-Llamazares Álvaro , Wall Jeffrey
Published: July 2021

The academic publishing world is rapidly changing. These changes are driven by and have implications for a range of intertwined ethical and financial considerations. In this essay, we situate Journal of Ethnobiology (JoE) in the discourse of ethical publishing, broadly, and in ethnobiology, specifically. We consider it an ethical imperative of JoE to promote the core values of the field of ethnobiology as a platform for scholarship that is both rigorous and socially just. We discuss here the many ways JoE addresses this imperative, including issues of diversity, accessibility, transparency, and how these efforts contribute to our ongoing relevance. We find that JoE has achieved high ethical standards and continues to raise the bar in our field. However, the growing incongruity between monetary solvency and best practices could threaten JoE's longevity unless we keep adapting to the changing landscape. Looking to the future, we encourage all ethnobiologists to participate in the ongoing process of improving ethics in publishing, including careful consideration of where to publish precious ethnobiological knowledge.
Pencarian Data Barang Produk Atribut Sekolah Menggunakan Algoritma Binary Search
Authors: Aviantika Risma Dara Awal , Kustanto Kustanto , Hasbi Muhammad
Published: July 2021

ABSTRACTTechnology and information that is growing and sophisticated must be balanced according to the needs. For it was made the application of binary algorithms for the search data goods production of school attributes. Many methods in search with the goal of making it easier to search, e.g. search data of production items of school attributes with binary search method. Convection in the search of production goods using the manual way by looking for the archive data written in the notebook, the purpose of this research is to create a data retrieval system of goods that will be applied as a data retrieval tool of goods, as well as change the system manual to the computing system. In this research using Binary Search algorithm. Binary search algorithm is a technique applied only on the sorted element (sorted). This research using method of binary search algorithm with analysis stage, system design, coding/construction, testing, and implementation. In the analysis stage, the collection of data conducted is observation and literature study. At the system design stage using Unified Modelling Language (UML) include the use case diagram, activity diagram, Sequence diagram, and Diagram class. At the construction stage using the Java programming language using Netbeans and MySQL Server tools while the implementation of this system is the application of data retrieval of goods. To know the eligibility of a system, it is necessary to test against the search time of 210 data each time duration, 0.0004 seconds, 0.0005 seconds, 0.0006 seconds, 0.0007 seconds, 0.0008 seconds, 0.0009 seconds, 0.0010 seconds, 0.0012 seconds, 0.0014 seconds, 0.00117 seconds. The final result of this study is the application of search for production goods with Binary Search Algorithm Method.
Lo spagnolo che traduce nella storia
Lettura critica di El tabaco que fumaba Plinio
Authors: Patat Alejandro
Published: July 2021

This chapter aims to analyse the hypotheses and theses of El tabaco que fumaba Plinio. Escenas de la traducción en España y América: relatos, leyes y reflexiones sobre los otros, edited by Marietta Gargatagli and Nora Catelli and published in 1998 by Ediciones del Serbal (Barcelona). The book is an anthology in Spanish and not only does it include texts translated into Spanish, but multiple documents (premises, laws, reflections, myths) on the act of translating. According to the editors, the long history of the relationship between the Spaniards and the Other highlights from the outset different strategies of appropriation, domestication, acclimatisation and rewriting which also drew on the domination, exclusion and omission of the Other’s voice.
List of Books from the Port of Piraeus
Authors: Dardano Valentina
Published: July 2021

The inscription, carrying part of a list of books, was found in the surroundings of the port of Piraeus. Some scholars think that it belongs to a library’s catalogue; according to others, it might record a donation offered to a gymnasium’s library. The inscription is of great interest as both a historical and paraliterary document. On the one hand, it is an asset for the study of book circulation and the emergence of public libraries in the Hellenistic age. On the other hand, it provides useful data about otherwise unknown or highly fragmentary texts, and it is a key witness in the history of tradition of all the books mentioned.
TINJAUAN SINGKAT TEKNOLOGI PRODUKSI BIOHIDROGEN MELALUI KONVERSI BIOMASSA
Authors: Amalia Rafika , Sinaga Nazaruddin , Suedy Sri Widodo Agung
Published: July 2021

Kekhawatiran akan emisi gas rumah kaca dan krisis energi yang semakin dirasakan negara-negara didunia khususnya di Indonesia menyebabkan perlu dilakukan pengembangan energi alternatif yang bersih dan ramah lingkungan. Biohidrogen yang diperoleh dari biomassa dapat menjadi alternatif terbaik untuk  mengatasi permasalaan tersebut. Penelitian ini dilakukan dengan tujuan untuk memberikan gambaran dari produksi biohidrogen berdasarkan penilitian-penelitian yang sudah ada sehingga dapat dilakukan pengembangan produksi biohidrogen melalui konversi biomassa di Indonesia. Penelitian ini dilakukan dengan studi literatur, pengumpulan data dilakukan dari penelitian-penelitian yang sudah ada untuk mengetahui proses yang sesuai dan bisa diterapkan untuk produksi biohidrogen melalui konversi biomassa di Indonesia. Analisis dalam penelitian dilakukan menggunakan perbandingan dari setiap literatur, sehingga diperoleh proses dan teknologi yang sesuai untuk produksi biohidrogen. Hasil penelitian menunjukkan pemanfaatan teknologi biohidrogen melalui konversi limbah biomassa dengan proses fermentasi anaerob pada kondisi termofilik adalah pilihan yang tepat, karena dapat menghasilkan yield yang tinggi. Untuk menunjang produksi biohidrogen yang optimal perlu diperhatikan beberapa faktor diantaranya yaitu pH, substrat, suhu, dan kondisi operasi. Jumlah biomassa yang melimpah di Indonesia dapat memudahkan produksi biohidrogen secara berkelanjutan.Kata kunci : krisis energi, biohidrogen, dark fermentation
EVALUASI PENGARUH PRODUCT QUALITY, PRODUCT INNOVATION DAN MARKETING PROMOTION TERHADAP BRAND IMAGE IKEA
Authors: Putra I Gede Wisnu Satria Chandra
Published: July 2021

Penelitian ini bertujuan untuk menganalisis pengaruh Kualitas Produk, Inovasi Produk dan Promosi Pemasaran terhadap Citra Merek. Objek penelitian ini adalah konsumen IKEA di Alam Sutra - Tangerang. Penelitian ini dilakukan pada 100 responden dengan menggunakan teknik convenience sampling dan menggunakan program SPSS 22.00 sebagai alat pengolahan data. Hasil penelitian ini menunjukkan bahwa secara simultan variabel Kualitas Produk, Inovasi Produk, dan Promosi Pemasaran memengaruhi Citra Merek IKEA di Alam Sutra - Tangerang. Ini telah dibuktikan dari hasil uji simultan (F). Namun hasil (t) uji parsial menunjukkan titik signifikan pada salah satu dari tiga variabel independen yang mendukung hipotesis. Oleh karena itu, asumsi yang diterima adalah, hanya ada pengaruh antara Inovasi Produk dengan Citra Merek IKEA di Alam Sutra – Tangerang

Kata kunci: Kualitas Produk, Inovasi Produk, Promosi dan Pemasaran, Citra Merek

 

This research aimed to analyze the influence of Product Quality, Product Innovation and Marketing Promotion to Brand Image. The object of this research is consumer of IKEA in Alam Sutra - Tangerang. This research was done to 100 respondents by using convenience sampling technique and using the SPSS 22.00 program as a data processing. The result of this research shows that simultaneously, the variable of Product Quality, Product Innovation and Marketing Promotion influence the Brand Image of IKEA in Alam Sutra - Tangerang. It has been proven from the result of (F) simoultant test.  However the result of (t) partial test shows significant point on one of three independent variables that supports the hipothesis. Therefore, the accepted assumption is, there is influence only between Product Innovation to Brand Image of IKEA in Alam Sutra – Tangerang

Keywords:  Product Quality, Product Innovation, Marketing Promotion, Brand Image
Randomized Clinical Trial to Evaluate the Effect of Canephron N in Comparison to Ciprofloxacin in the Prevention of Postoperative Lower Urinary Tract Infections after Midurethral Sling Surgery
Authors: Rechberger Ewa , Rechberger Tomasz , Wawrysiuk Sara , Miotla Pawel , Kulik-Rechberger Beata , Kuszka Andrzej , Wróbel Andrzej
Published: July 2021

Urinary tract infections (UTIs) are one of the most common reasons for antibiotic prescriptions among women worldwide. UTIs are also associated with intra- and postoperative catheterization, which is an essential component of many gynecological surgical procedures, including midurethral sling (MUS) placement.

The aim of this study was to compare the incidence of UTI subsequent to a MUS procedure.

The study involved 562 female patients who underwent MUS procedures due to stress urinary incontinence (SUI). Patients were assigned in a 1:1 ratio to two study groups: patients receiving 500 mg of ciprofloxacin three times a day for 3 consecutive days after surgery or patients receiving 5 mL of Canephron taken orally three times a day for 3 weeks.

After analyzing the collected data, it was found that in the group of patients receiving ciprofloxacin, 29 women (10.98 %) had a UTI, whereas in the group of patients receiving Canephron, 36 women (13.64 %) had a UTI within 6 months after the patient’s MUS procedure. No statistically significant difference between the two groups was noted. Postoperative prophylaxis with a phytodrug can be perceived as an attractive option in the reduction of antibiotic consumption among female patients after a MUS procedure.
Features of the Course and Treatment of Osteoarthritis in Patients with Osteoporosis and Obesity
Authors: Tsymbaliuk Tetiana , Krylova Anna , Dubkova Antonina
Published: July 2021

The objective: features of the course and clinical manifestations of the joint syndrome and increase the effectiveness of treatment in patients with OA with osteoporosis and obesity.
Materials and methods. The study included 134 patients (88 women and 46 men), aged 30 to 80 years. Depending on the body mass index, patients were divided into 2 groups: obese and normal weight. Peculiarities of the course and effectiveness of treatment were assessed using questionnaires VAS, WOMAC, Lekens. Levels of nonspecific inflammatory parameters (ESR and CRP), cytokines (IL-1, IGF-1, NO), uric acid level and bone mineral density were also studied. SPSS Statistics was used for statistical data processing.
Results. The study revealed a statistically significant difference in the indicators of the questionnaires VAS, WOMAC and Leken, levels of immunological (IL-1, IGF-1, NO) and nonspecific (ESR, CRP) indicators of inflammation between the 2 groups of patients. Patients with osteoporosis and obesity had the worst questionnaires and indicators of inflammation, compared with patients with normal BMD and osteopenia. In obese patients, the dynamics of treatment was significantly worse, according to questionnaires, immunological and nonspecific indicators of inflammation.
Conclusions. Patients with OA and obesity, compared with normal weight, had more severe joint damage, more intense pain, stiffness and reduced functional activity, as well as more intense inflammation. The most severe course of the disease was observed in patients with osteoporosis and obesity, compared with normal BMD and osteopenia. The dynamics of SYSADOA treatment is impaired in patients with osteoarthritis and obesity: less intense reduction of knee stiffness, pain and poorer functional activity, as well as less effective anti-inflammatory effect.
Efficiency of Using Vita-melatonin in Patients with Non-alcoholic Fatty Liver Disease in Combination with Chronic Pancreatitis and Type 2 Diabetes Mellitus
Authors: Sirchak Yelizaveta , Hryha Vasyl , Barani Vasyl , Reho Oleksandra
Published: July 2021

The objective: to analyze the effectiveness and feasibility of complex therapy with the use of a melatonin preparation in patients with nonalcoholic fatty liver disease (NAFLD) in combination with chronic pancreatitis (CP) and type 2 diabetes mellitus (DM).
Materials and methods. We examined 64 patients with NAFLD in combination with CP and type 2 diabetes (mean age – 48.9 ± 5.4 years). The control group included 20 practically healthy individuals: 12 (60.0 %) men and 8 (40.0 %) women (average age – 47.6 ± 5.8 years). The patients were divided into two groups depending on the prescribed treatment: Group I (n = 30) – patients received only basic therapy (BT), Group II (n = 34) – patients were prescribed melatonin in addition to BT (Vita-melatonin, firm PJSC «Kiev Vitamin Plant», Ukraine) at a dose of 3 mg per day 30 minutes before bedtime for 1 month. All patients with NAFLD in combination with CP and type 2 diabetes before and after treatment were examined by general clinical, anthropometric, instrumental and laboratory methods. To verify the diagnosis, attention was paid to the nature of the complaints, the medical history.
Results. The results of the study make it possible to recommend the melatonin preparation as part of the complex treatment of patients with NAFLD in combination with CP and type 2 diabetes due to its antioxidant, anti-inflammatory properties, as well as its ability to influence cognitive changes in these patients.
Conclusion. The drug melatonin (Vita-melatonin) is an effective, safe agent for the complex treatment of patients with NAFLD in combination with CP and type 2 diabetes. Normalization of the serum melatonin level in patients with NAFLD in combination with CP and type 2 diabetes with the use of melatonin leads to a decrease and / or normalization of the indicators of cognitive status in these patients.
Polypharmacy in the Treatment of Arterial Hypertension and Heart Failure
Authors: Dolinska Sofiia , Potaskalova Viktoriia , Khaitovych Mykola
Published: July 2021

Due to the development of the pharmaceutical industry, today there are a large number of drugs with similar properties and efficacy, but little-studied pharmacodynamics and pharmacokinetics. There fore many medicines are prescribed more often and in larger quantities than necessary. That is why patients and doctors often face the problem of polypharmacy in various fields of medicine including cardiology.
The paper presents the results of the analysis of 249 case histories of inpatients with cardiac profile. All patients with underlying cardiac pathology (arterial hypertension, ischemic heart disease) had concomitant diseases. Patients with arterial hypertension had other concomitant diseases, most often gout, diseases of the digestive system, anemia. Chronic heart failure was found in the majority of patients with arterial hypertension, ischemic heart disease, chronic rheumatic heart disease.
We have determined which pharmacological groups of drugs are prescribed to patients with arterial hypertension or chronic heart failure and concomitant diseases: more than 60 % of patients are prescribed drugs that are unsuitable for their condition. We analyzed and compared treatment standards in Ukraine and the world and carried out that doctors in Ukraine use modern and effective methods of treatment. The risks of prescribing a large number of drugs to patients are analyzed and the risks of dangerous drug interactions that can threaten the life or health of the patient are identified. In particular, in the treatment of cardiac patients, doctors used combinations of calcium antagonists and beta-blockers, NSAIDs and antithrombotic drugs, corticosteroids and antibacterial drugs of the fluoroquinolone group, ACE inhibitors and potassium-preserving diuretics, antiarrhythmic drugs and highly active diuretics, etc.
We compared medicinal prescriptions for the treatment of cardiovascular diseases with an interval of 10 years and revealed that in 2008 the therapy often did not comply with the international and Ukrainian treatment protocols, however, in 2018, unwanted drug interactions were found 4 times less often. That reflects the trend of doctors’ awareness of pharmacology and evidence-based medicine.
Elderly Patient with Hypertension in General Practice: Clinical Features and Antihypertensive Therapy
Authors: Zhdan Viacheslav , Kitura Yevdokiia , Babanina Maryna , Kitura Oksana , Tkachenko Maksym
Published: July 2021

The prevalence of arterial hypertension (AH) increases with age: among people over 60 years old this index is more than 2 times higher in the general population, 2/3 of people over 65 years old suffer from hypertension. Among patients 65–89 years old with hypertension, 2/3 patients have isolated systolic hypertension (ISAG).
Features of hypertension in the elderly patients are: lability of blood pressure (BP), increasing frequency of pseudohypertension, high frequency of «white coat hypertension», decreased sensitivity of pressor factors for antihypertensive drugs, high frequency of resistant to treatment of hypertension.
The new recommendations of the European Society of Cardiology for the diagnosis and treatment of hypertension emphasize 2 groups of elderly patients: 65–79 years old and ≥80 years old, which described the epidemiological features, the prevalence of risk factors for cardiovascular events, blood pressure levels for antihypertensive therapy and target blood pressure, and the recommended principles of drug therapy that are different from young and middle-aged patients. For most patients, fixed combinations are indicated as starting AGT, but monotherapy is recommended for the treatment of hypertension in very elderly patients (over 80 years old) and elderly patients over 65 years old with senile asthenia. The decreasing of blood pressure should be gradual, taking into consideration the increased risk of orthostatic reactions at this age.
European and American experts recommend os first-line drugs low doses of thiazide diuretics and calcium channel antagonists (mainly dihydropyridine), which are especially indicated in isolated systolic arterial hypertension to effectively reduce the frequency of cardiovascular complications in the treatment of elderly patients with hypertension.
Ultrasound Diagnosis of Abnormalities in the Development of the Uterus and Vagina with Impaired Menstrual Blood Flow in Girls
Authors: Sadovoy Andrii
Published: July 2021

The objective: to study and analyze the indicators of the diagnostic informativeness of the echographic study of anomalies in the development of the uterus and vagina with impaired outflow of menstrual blood in girls.
Materials and methods. For the study, a group of 37 patients (n=37), from 10 to 19 years old, was selected, who were divided into 2 subgroups: 1 subgroup – patients with doubling of the uterus and vagina without disturbing the outflow of menstrual blood (n=25), 2 subgroup – patients with doubling uterus and vagina with partial aplasia of one vagina (n=12). Most of the subjects – 26 girls (10,3 %) – applied for a referral to clarify the diagnosis, 11 (29,7 %) – without complaints from the genitals for differential diagnosis.
Results. At vaginoscopy at all patients the mucous membrane of pink color with well expressed folding. According to ultrasound of the pelvic organs in 1 subgroup in 17 patients the vagina was divided into 2 parts full, and in 8 – incomplete septum, two uteruses were located, parallel to each other, the contours were smooth, clear, M-echo was determined in both uteruses, two cervix with cervical canals. In subgroup 2, 9 patients showed protrusion of different sizes of one of the walls of the vagina, 2 patients in the lateral, 1 – in the upper lateral zone of the vagina was determined by a punctate hole with an inflammatory roller – fistulous entrance to the second vagina. In all patients from the side of the aplasia of the vagina, the uterine cavity is expanded from 10 to 25 mm, filled with echonegative contents. The reliability of the results of ultrasound scanning of anomalies of genital development is equal: the sensitivity of the method – 84,0 %, specificity – 90,9 %, accuracy – 89,1 %.
Conclusions. Manifestation of malformations of the genitals with impaired outflow of menstrual blood occurs at puberty, as after menarche above the aplastic segment of the genital tract accumulates menstrual blood and tumor formation, accompanied by characteristic clinical manifestations. Diagnosis of this pathology is quite complex, which can lead to errors in determining the nature of the pathological condition and, as a consequence, unwarranted surgery. Thus, the need to further improve the methods of diagnosis and management of patients with doubling of the uterus and vagina with impaired menstrual blood flow remains relevant, which will identify diseases at an earlier age or immediately after the appearance of complaints and symptoms.
Clinical Case of Fetal Lymphangioma
Authors: Sukhanova Aurika , Karlova Olena , Bankovska Nataliia , Kuzminska Olena
Published: July 2021

Lymphangioma is a benign lymphatic system tumor, often congenital, mainly affecting lymph nodes in various anatomic localizations. Postnatally mostly common lymphangioma manifestation occurs during the first year of life.
Today it can be readily diagnosed prenatally.
Diagnosis is based on non-invasive visualization, such as sonography and computed tomography.
The objective: is to present clinical case of manifest fetal lymphangioma diagnosed during pregnancy.
Fetal ultrasound (US) was performed at 28, 32, 34 weeks of gestation. As a result fetus was diagnosed with hypoechogenic mass in right axillary region, growing in dynamics gradually from 34×28 mm, 38×34 mm to 49×37 mm. Mass had clear even contours, hyperechogenic capsule with fine dispersed suspension content. Color doppler imaging showed avascular mass character.
After delivery at 37–38 weeks of gestation (planned Cesarean section) at newborn examination we visualized asymmetric soft elastic consistency protrusion along right midclavicular and anterior axillary region.
Described clinical case of fetal lymphangioma is a good illustration of dynamic prenatal and postnatal dynamic observation and its US interpretation.
The Efficacy and Safety of Using a Combined Iron Supplement in Children with Community-acquired Pneumonia and Anemia
Authors: Marushko Yurii , Hyshchak Tetiana , Khomych Olha
Published: July 2021

The article summarizes the own data and presents a scientific review of the medical literature devoted to the analysis of the problem of treatment of community-acquired pneumonia associated with anemia in children.

The objective: to optimize the treatment of community-acquired pneumonia associated with anemia in children.

Materials and methods. There were examined 100 children (53 girls and 47 boys) aged 9–17 years (the average age was 12.96 ± 0.07 years), who were treated for community-acquired pneumonia in the children’s clinical hospital No. 5 in Kiev. Children were divided into two groups: Group I – 70 patients with community-acquired pneumonia and normal levels of hemoglobin and erythrocytes; Group II – 30 children with pneumonia and anemia of the I – II stages.

Results. During the study of the localization of the pathological process in the lungs, it was found that in children of group II compared with group I, bilateral lung damage was more common (33.3 % compared to 12.9 %; p <0.05). The main indicators of peripheral blood in patients with community-acquired pneumonia and anemia were lower than in patients with community-acquired pneumonia. The clinical picture of community-acquired pneumonia with anemia and also there was analyzed the possibility of using a combined preparation of ferrous iron, manganese and copper for treatment.

Conclusion. It was found that in patients with community-acquired pneumonia and anemia, compared with patients with community-acquired pneumonia, there is a more widespread and severe inflammatory process in the lungs with prominent signs of intoxication. However, when using a medication of ferrous iron with trace elements, an improvement in indicators and the course of the disease is observed.
Thyroid Lesion as a Manifestation of Comorbidity in Patients with Diabetic Polyneyropathy
Authors: Chupryna Hennadii , Dubynetska Viktoriia
Published: July 2021

The study of clinical and anamnestic and paraclinical characteristics, highlighting their dominant features in patients with DP and existing thyroid diseases occupies an important place in modern neuroendocrinology and requires more focused attention of clinicians.

The objective: to determine the leading clinical and laboratory-instrumental parameters in patients with DP and thyroid pathology, to analyze the mutual influence of neuroendocrine pathology on the patient’s somatoneurological condition.

Materials and methods. Was done a clinical examination of 64 patients with DP , in 27 (42 %) of them was diagnosed the comorbid thyroid pathology, in 37 (58 %) it was absent. All patients were divided into two groups: with DP in the background of type I, II DM and thyroid pathology (A) and with DP in the background of type I, II DM without thyroid pathology (B). During the examination of patients were used clinical-anamnestic, clinical-neurological, laboratory-instrumental, neurophysiological methods of examination. Pain characteristics were assessed using the McGill Pain Questionnaire (MPQ). Statistic calculation was done in MS Excel 2003 and using the package for statistical analysis STATISTICA 10.

Results. In patients of both groups comorbidly were dominated diseases of the cardiovascular system, in group A, increasingly was revealed gastrointestinal pathology. Polyneuritic disorders of sensitivity and autonomic-trophic disorders are more common in persons of group B, they have a higher frequency of comorbid pathology and longer duration of DM. In group A lack of Achilles and knee reflexes was recorded more often than in comparison group. In 18 (65 %) of the examined persons of group A was detected a fatty liver dystrophy by ultrasound scanning of the abdominal organs, which exceeds the number in group B – 13 (35 %). There is an inverse average dependence between the level of TSH and BMI (correlation coefficient = –0,65). The general index of pain rating (Pain Rating Index – PRI) in group A is higher (30,62±2,64 scores).

Conclusions. Among the thyroid diseases in the examined patients of group A hypothyroidism was most often detected, so 30 % of patients had a pronounced violation of lipid metabolism in the form of obesity, besides, in this group the number of people with type II DM was prevailed. The influence of thyroid pathology on the manifestations of DP is reflected in the intensification of neuropathic pain syndrome. There is also a significant effect on the metabolism of fats and carbohydrates, which aggravate and sometimes deepen the somatic condition of the patient.
Influence of the Plant-citrate Complex on Indicators of Systemic Inflammation in Patients with Urolithiasis
Authors: Karpenko Olena , Petrova Anna
Published: July 2021

Treatment of urolithiasis is a complex task of modern medicine. The search for non-invasive methods of treatment, prevention of relapses and complications, slowing down the development of renal failure is an urgent issue of our time. The study demonstrated a comprehensive analysis of indicators of systemic inflammation in patients with urolithiasis and the effectiveness of using the plant-citrate complex.

The objective: to conduct a clinical assessment of systemic inflammation in patients with urolithiasis, to determine the effectiveness of the use of the plant-citrate complex of the drug Uriklar on the indicators of systemic inflammation.

Materials and methods. There were examined 52 (55.6 %) patients with urolithiasis, which were divided into two groups: Group I (main group) – 32 patients with urolithiasis who received the herbal citrate complex and Group II (comparison group) – 20 patients with urolithiasis. The control group included 20 almost healthy individuals. All patients underwent clinical and laboratory tests: general and biochemical blood tests to determine the parameters of iron metabolism, lipid profile, CRP, determination of the levels of cytokines in the blood, blood pressure, body mass index.

Results. The results of this study demonstrate the development of systemic inflammation in patients with urolithiasis, determined by a decrease in GFR. Against the background of the treatment with Uriklar, a decrease in the levels of pro-inflammatory cytokines, CRP and ferritin is observed, which indicates the anti-inflammatory properties of the drug.

Conclusion. Such properties of the plant-citrate complex are pathogenetically substantiated and can be recommended for urolithiasis, which, along with the therapeutic properties, allows to obtain the provision of metaphylaxis of urolithiasis and to slow down the rate of development of chronic kidney disease.
Topical Issues in Diagnosis of Coagulopathies and Prevention of Thromboembolic Complications of Atrial Fibrillation in Patients with Liver Cirrhosis
Authors: Chernyavsky Volodymyr , Baylo Alina
Published: July 2021

Nowadays the comorbid pathology of liver cirrhosis and atrial fibrillation has been widely discussed and reported in the literature in the light of recent findings from the study of the effectiveness and safety of anticoagulants in this category of patients. The review is devoted to summarizing the existing data on the comorbid course of these diseases from the point of view of the impact of bleeding and thrombosis on the quality of life and mortality of patients and the possibility of using new methods of diagnosis and prevention of these complications.
The purpose of the review is to focus the attention of physicians and researches on the relevance and prevalence of comorbid course of liver cirrhosis and atrial fibrillation, their complications, and discuss the benefits and possibilities of applying global methods of hemostasis assessment and anticoagulants in clinical practice.
This article examines the main pathophysiological aspects of «rebalanced hemostasis» theory in liver coagulopathies, its effect on the onset of bleeding and thrombotic events, and considering the clinical benefit of the use of anticoagulants. The disadvantages of traditional coagulation assessment tests compared to the benefits of thromboelastometry (ROTEM) and thromboelastography (TEG), general fulfilling principles and evaluation of their indicators are discussed. Existing research findings on the safety and efficacy of warfarin and direct oral anticoagulants in patients with liver cirrhosis and atrial fibrillation compared with no treatment are highlighted.
Diagnostic Value of Heart-type Fatty Acid Binding Protein in Group of Patients with NSTEMI at the Time of Application for Medical Care
Authors: Sid Yevhen , Kulbachuk Oleksandr
Published: July 2021

The relevance of the early detection of myocardial necrosis is due to the difficulties of differential diagnosis in the first hours of the development of acute coronary syndrome. Therefore, the doctors of the first contact, as before, are interested in an early cardiac marker and the presence of tests based on it. Heart fatty acid binding protein (h-FABP) is a cardiac marker that increases in the blood to diagnostic values after just one hour from the beginning of clinical manifestations.

The objective: to determine the diagnostic value of heart fatty acid binding protein in group of patients with NSTEMI.

Materials and methods. We examined 280 patients with STEMI, 91 patients with NSTEMI, 76 with stable angina pectoris. Blood samples were taken from all patients at the first contact to determine troponin I, a heart fatty acid binding protein and CPK-MB. Patients with NSTEMI were divided into three subgroups: the first – up to 3 hours from the onset of symptoms, the second – from 3 to 6, the third from 6 to 12. The level of heart fatty acid binding protein in plasma was determined by enzyme immunoassay.

Results. The early detection of AMI in people visiting primary care doctors with chest pain continues to be a challenge. Undoubtedly, cardiac troponins are the “gold standard” for the diagnosis of AMI, but early detection of these can give a negative result. The results of the studies show a high diagnostic efficacy of h-FABP in the early diagnosis of AMI, and it is superior in sensitivity (in the first hours from the onset of the disease) to cardiac troponins. So, for example, in the subgroup of patients with the onset of symptom manifestation up to 3 hours for h-FABP with a cut-off >0,48 ng/ml, the sensitivity was 92.7 % and specificity was 97,3 % (AUC=0,99; 95 % CI AUC 0,942–0,998). In the same subgroup, troponin I had a specificity of  22,0 %, with cut off >0,84 ng/ml (AUC=0,71; 95 % CI AUC 0,615–0,787).

Conclusions. The level of cardiac protein that binds fatty acids is significantly increased in patients with acute myocardial infarction compared with stable coronary heart disease.
Parameters of Quality of Life and Metabolic Disorders in Women Who Underwent on Hysterectomy with Uterine Myoma
Authors: Proshchenko Olha , Ventskivsky Borys , Ventskivska Iryna
Published: July 2021

Today, there are more and more reports of an increase in the proportion of patients with uterine fibroids (up to 45 %), in whom hysterectomy (HE) remains the only radical method of recovery. Over the past decades, views on this operation have changed significantly. HE and its influence on somatic and psychological status, psychogenic changes and vegetative-neurotic manifestations associated with postoperative acute circulatory ischemia of ovarian tissue have become the subject of scientific exchange in many discussion panels.The article presents data from an experimental psychological study, assessment of the severity of urogenital dysfunction using the standardized POP-Q system, characteristics of quality of life parameters, indicators of carbohydrate and lipid metabolism both at the stage of preoperative followup and within 12 months, 3 and 5 years after surgery. in 80 women of reproductive age with uterine fibroids who underwent vaginal hysterectomy.The comparison group included 60 patients with abdominal hysterectomy. As a result of the studies carried out using experimental psychological methods, the dominance of asthenic, anxiety and depressive disorders should be noted. The most common symptoms were decreased performance, mood, emotional lability, dyssomnia, decreased memory and concentration.The study of the parameters of the quality of life made it possible to note the lowest indicators in the older age category of the main group, low levels of parameters were recorded in relation to «physical» and «sexual health», the sphere of interpersonal relationships suffered less.After GE, an increase in body mass index, systolic and diastolic blood pressure, an increase in proinsulin and HOMA index, as well as very low density lipoprotein cholesterol and an atherogenic index were recorded.
Determination of Anthracene Derivatives in Herbal Medicines
Authors: Evdokimova O. V. , Beketova A. V. , Lyakina M. N.
Published: July 2021

The relevance of this study stems from the need for alignment of test methods used for identification and assay of anthracene derivatives in herbal preparations and herbal medicinal products. The aim of the study was to analyse Russian and international quality standards and to identify the most specific and sensitive test methods that could be used for herbal medicines containing anthracene derivatives. The comparative analysis of requirements in the Identification, Determination of major classes of bioactive compounds, and Assay parts of the Russian and foreign pharmacopoeial monographs for herbal preparations and herbal medicinal products containing anthracene derivatives, demonstrated that the main test method used for identification is thin layer chromatography, while assays most often rely on spectrophotometry. The so-called “consistent standardisation” principle is implemented in the Russian quality standards as regards alignment of methods used for anthracene derivative determination in herbal preparations (i.e. active pharmaceutical ingredients, APIs) and herbal medicinal products containing these APIs. The comparative analysis of requirements in the Russian and foreign quality standards for herbal medicines containing anthracene derivatives demonstrated the need for elaboration of two general chapters: Qualitative analysis of anthracene derivatives in herbal medicines and Quantitative analysis of anthracene derivatives in herbal medicines.
Hatay İli Dörtyol İlçesinde Portakal Üretim ve Pazarlaması
Authors: ATLI Hüseyin Fatih , SAHİN Ahmet
Published: July 2021

Dünyada turunçgil üretiminin yaklaşık %50’sini portakal oluşturmaktadır. Türkiye dünya portakal üretiminde 7. sırada yer almakta ve portakal üretiminin yaklaşık %4’ünü karşılamaktadır. Tüketim artışına bağlı olarak ekonomik değeri de sürekli artan portakal dış pazarlarda daha çok portakal suyu olarak rağbet görmektedir. Türkiye’nin portakal üretimi ağırlıklı olarak, Washington, Yafa ve diğer portakal çeşitlerinden oluşmaktadır. Portakal üretiminin %83’ünün yapıldığı Akdeniz Bölgesinde üretim sırasıyla Antalya, Adana, Hatay ve Mersin illerinde daha çok yapılmaktadır. Türkiye’de portakal üretiminin %17’sinin yapıldığı Hatay ilinde üretim Dörtyol ve Erzin ilçelerinde yoğunlaşmaktadır. Bu çalışmada portakal üretiminin Dörtyol ilçesindeki durumu ve pazarlanma ile ilgili sorunlara çözüm önerilerinin ortaya konulması amaçlanmıştır. Dörtyol ilçesinde portakal üretimi yapan 91 üreticiyle yapılan anketler sonucu elde edilen veriler çalışmanın ana materyalini oluşturmuştur. Araştırma sonuçlarına göre işletmelerde turunçgil arazi varlığı ortalama 47,31 da olarak belirlenmiştir. Portakal üretiminde dekara düşen ağaç sayısı 20,94 adet/da ve ortalama ağaç verimi 160,00 kg/adet olarak saptanmıştır. Portakal üretiminde ağaç başına brüt kâr 52,13 TL/adet olarak saptanmıştır. Araştırma sonuçlarına göre ürün pazarlamada en önemli risk faktörünün %17,31 ile fiyat belirsizliği olduğu ve üretimde ise en önemli üretim risk faktörünün %10,67 ile üretim teknolojisi olduğu belirlenmiştir. Sonuç olarak fiyat belirsizliğini ortadan kaldıracak şekilde tüketimi 12 aya çıkaracak çeşitlerin geliştirilmesi ve tüketimi arttıracak şekilde üretimin işlenmesine yönelik çalışmalar yapılmasına ihtiyaç vardır.
Quince A Anacının Çöğür Anacı Olarak Kullanım Potansiyelinin Belirlenmesi
Authors: ŞAHİN Müge
Published: July 2021

Yumuşak çekirdekli meyve türleri içerisinde üretimi en yüksek olan 3. tür ayvadır ve artan üretim ile birlikte uygun anaçlara olan ihtiyaçta artış göstermektedir. Son zamanlarda anaç üretiminde vejetatif yöntemlerin yaygın olarak kullanılmasının yanı sıra bu yöntemdeki bazı dezavantajlardan dolayı generatif yöntemlerinde kullanımı yüksektir. Bu çalışmada, dünyada yaygın olarak hem ayva hem de armut ve yenidünya için anaç olarak kullanılan Quince A anacının çöğür anacı olarak kullanım potansiyeli araştırılmıştır. Tohumlara + 4 C0 de 8 hafta soğuk katlama uygulaması yapılmış ve maksimum çimlenme oranına (% 73.5), tohum ekiminden 25. gün sonra ulaşılmıştır. Çöğür gelişimi ile ilgili gövde çapı, sürgün boyu ve pişkinlik oranı parametreleri ve bunların minimum, maksimum, ortalama, standart sapma ve varyasyon katsayıları belirlenmiştir. Gövde çapı 4.91-7.98 mm, sürgün boyu 20.02-46.60 cm, pişkinlik oranı ise 2.86-8.34 cm/mm arasında değişim göstermiştir. Varyasyon katsayıları, gövde çapı için % 11.99, sürgün boyu için % 23.48 ve pişkinlik oranı için ise % 22.80 olarak belirlenmiştir ve hem çimlenme hem de homojen çöğür gelişimi açısından Quince A’nın çöğür anacı olma potansiyelinin yüksek olduğu tespit edilmiştir.
Kırşehir’de Yetiştirilen Cemele Biberinin Biyoaktif Bileşenlerinin ve Antioksidan Kapasitesinin Belirlenmesi
Authors: ERGÜN Fatma
Published: July 2021

Canlılar, yaşamsal faaliyetlerinin sağlıklı bir şekilde devamı için metabolik faaliyetleri sonucu veya dış etkilere bağlı olarak bünyelerinde oluşan zararlı serbest radikalleri organizmalarından uzaklaştırmak zorundadırlar. Bunu antioksidanlar sayesiyle yapabilirler. Ayrıca antioksidanlar gıdaların bozulmasını engelleyerek raf ömrünün artmasına neden olurlar. Bu durum doğal veya sentetik antioksidanlara olan ilginin artmasına sebep olmuştur. Ancak sentetik antioksidanların kanserojen ve toksik özelliklerinin olduğunun bilinmesi doğal antioksidanlara olan ihtiyacın artmasına ve önem kazanmasına neden olmuştur. Cemele biberi hafif acı tadıyla Kırşehir’de yaygın olarak üretilen, yaş ve kuru olarak tüketilen biber çeşididir. Bu çalışmada Cemele biberinin hekzan ve metanol ekstraklarının toplam fenolik ve flavonoid madde miktarları tayin edildi. Hekzan ekstraklarında fenolik ve flavonoid madde miktarlarının metanol ekstraklarına göre daha fazla olduğu belirlendi. Antioksidan kapasitesi 1,1-Difenil-2-pikrihidrazil (DPPH) Radikal süpürücü kapasite yöntemi (DPPH) ile belirlenerek IC50 değerleri hekzan ekstraktı için 242.52 g mL-1, metanol ekstraktı için 195.85 g mL-1 olarak hesaplandı. Ayrıca indirgeme gücünün hekzan ekstraktında daha fazla olduğu Fe3+-Fe2+ İndirgeyici antioksidan gücü (FRAP) yöntemi ile belirlendi. Sonuç olarak, Cemele biberinin günlük diyetimize taze ve kurutulmuş şekilde dahil edilmesinin organizmamız için gerekli olan antioksidan ihtiyacının bir kısmının karşılanması açısından önemli olabileceği, ayrıca endüstriyel kullanımının ve sağlık üzerine etkilerinin belirlenmesi için yeni çalışmaların yapılmasının gerekliliği düşünülmektedir.
Exploring Apology Strategy by Indonesian Public Figures: A Pragmatic Study in Social Media
Authors: Abudin Budi , Sundari Hanna
Published: July 2021

Public figures tend to use social media platforms to apologize in public due to its practicality and effectiveness. Although public apology as a social phenomenon has been extensively studied in the English-speaking world, Indonesian public apologies have less attention from linguists and management scientists. This paper examines the speech act of apologizing made by Indonesian Public Figures in 2020 by analyzing videos collected from YouTube. The data of the study was analyzed based on Murphy’s framework of formulate (2015). Findings include that Indonesian public figures prefer all three categories of apology strategy: explicit, conventional-indirect, and non-conventional-indirect strategies. Mover, explanation, account, or excuse become the most frequent used to express their apology. It was then followed by expression of lack of intent and statement of repair.

 

Keywords: Pragmatic, Apology, Indonesia, Youtube, Public Figures

 
RANCANG BANGUN PENGELOMPOKAN BAKAT KEMAMPUAN BEKERJA BERBASIS DEKSTOP PADA TELKOMSIGMA JAKARTA
Authors: Triansyah Jully , Aji Dicky Rodika
Published: July 2021

Abstract : With the existence of highly advanced information technology as it is today, it is certainly very helpful for human work in creating, changing and seeking information. The process of searching for information at Telkomsigma Jakarta still uses a system that is not well computed. In designing this talent grouping application, the author uses the C # language as a language to compile logic and uses visual studio as an application to display C # language logic lines and acts as an IDE so that the logic lines that have been compiled can be processed into an application, and use devexpress as an additional application for visual studio which contains controls that can help to create an application.The method used in developing this system uses the Extreme Programming method, while the methods for collecting the funds use observation, interviews and literature study.By utilizing this work ability grouping application, it makes it easier for users to map the information needed about the ability of each employee to work. Keyword : Ability, C#, DevExpress, Extreme Programming, IDE
Sistem Informasi Penerimaan Pegawai Pada PT.Sianyu Perkasa
Authors: Saputra Rama , Handayani Tuti , Rosdiana Rosdiana
Published: July 2021

Tujuan utama dari proses penerimaan pegawai adalah untuk mendapatkan orang yang tepat pada penempatan yang tepat pula sehingga sesuai dengan kondisi dan kebutuhan organisasi atau perusahaan. Permasalahan yang dihadapi perusahaan dimulai dengan bagaimana menyajikan informasi yang dapat mempermudah bagian perekrutan tenaga kerja dalam menangani proses penerimaan pegawai. Penulis melakukan beberapa batasan antara lain sistem pendukung ini digunakan oleh HRD selaku bagian perekrutan tenaga kerja. Serta Sistem ini hanya digunakan sebagai proses penerimaan tenaga kerja di PT. Sianyu Perkasa. Model pengembangan sistem yang digunakan adalah model proses waterfall yang bersifat sistematis dan berurutan. Perancangan sistem ini menggunakan bahasa pemrograman Java dan XAMPP sebagai web server yang didukung dengan MySQL sebagai pengolah datanya. Beberapa hal yang didapat dari penelitian ini adalah sistem informasi ini dapat memudahkan penyajian informasi mengenai penerimaan pegawai yang diolah oleh bagian HRD. Serta sistem informasi ini mempermudah proses penyeleksian data calon pegawai dan pembuatan laporan. Saran yang dapat penulis sampaikan dalam penelitian ini adalah perlu adanya pelatihan penggunaan sistem informasi ini kepada bagian HRD dan sistem informasi dapat dikembangkan sesuai dengan perubahan kebutuhan perusahaan nantinya.
Rancang Bangun Aplikasi Sistem Informasi Kegiatan dan Transparansi Keuangan Rukun Warga 04 Graha Mitra Citra Panongan
Authors: Rusdianto Hengki , Destriana Rachmat , Prastyawan Bayu Enggar
Published: July 2021

Rukun Warga (RW) adalah lembaga masyarakat yang dibentuk melalui musyawarah dengan masyarakat setempat untuk memberikan layanan kepada warga. Rukun Warga (RW) memiliki peran penting dalam menjaga dan melestarikan nilai-nilai kehidupan masyarakat berdasarkan kerjasama dan kekerabatan. Dalam memfasilitasi pelaksanaan pekerjaan pemerintahan dalam pembangunan dan masyarakat pedesaan atau perkotaan, dan kesejahteraan masyarakat. Oleh karena itu, Rukun Tetangga (RT) dan Rukun Warga (RW) harus memberikan layanan yang baik bagi warga yang menciptakan masyarakat yang kondusif. Masyarakat membutuhkan layanan serta transparansi keuangan setiap saat, tetapi layanan hanya dapat diberikan kepada warga di siang hari atau pada hari libur saja karena Pengurus Rukun Warga (RW) memiliki kepentingan pribadi. Masalah-masalah ini dapat diatasi dengan membangun sistem informasi berbasis website yang mampu menjadi media komunikasi antara Warga dan Pengurus Rukun Warga (RW). Dalam hal ini penulis menggunakan bahasa Unified Modelling Language (UML) digunakan untuk menganalisis desain sistem yang akan dibuat, untuk pengujian dilakukan dengan menggunakan metode pengujian Black Box, serta MySql sebagai database dan bahasa pemrograman yang digunakan adalah PHP.
PERANCANGAN APLIKASI INFORMASI BENGKEL MOBIL DAERAH JAKARTA BARAT BERBASIS ANDROID
Authors: Usup Rizky Muhammad , Susafaati Susafaati
Published: July 2021

The vehicel describe wrong one tool transportation that most needed as a means transportation in activity daily. Driver or riders normally have desire while driving i.e comfort in driving. driver could get comfort in driving with service vehicle an routine. car workshop is a place to fix vehicle that broke down or do service an rutin. author aims designing application this to assist driver get information abbout car workshop nearby and prevent occurrence accident result rarely do service vehicle car. Method algorithm that used in designing application this i.e use method algorithm djikstra. Algorithm Dijkstra is algorithm determine distance shortest from point A to point B. Application this also use google maps as map that could ease users to location car workshop that headed. With availabity application is be expected can help and facilitate consumer within doing activity in Jakarta Barat, if having problems vehicle to heave. Keywords : Djikstra, Car Workshop, Android