bluuebunny/crossref_metadata_2025 huggingface dataset:
P.55 Dietary Nitrate Prevents Progression of Carotid Subclinical Atherosclerosis Through BP-Independent Mechanisms in Patients with or at Risk of Type 2 Diabetes Mellitus: Results from the Double-Blind, Randomized-Controlled, Factorial Vasera Trial
Authors: Morselli Franca , Faconti Luca , Mills Charlotte E , Morant Steve , Chowienczyk Philip J , Cruickshank J Kennedy , Webb Andrew J , Cavarape Alessandro
Published: December 2020

Background

Epidemiological and animal studies suggest the potential of dietary nitrate (NO3− ) to inhibit atherogenesis. Spironolactone may improve arterial stiffness. We tested if 6 months’ intervention with dietary nitrate and spironolactone could affect carotid subclinical atherosclerosis and stiffness versus placebo/doxazosin, to control for blood pressure (BP), in a population with or at risk of type 2 diabetes [1].

Methods

A subgroup of participants in our double-blind, randomized-controlled, factorial VaSera trial were randomized to nitrate-containing beetroot juice or nitrate-depleted juice, and spironolactone or doxazosin. Ultrasound for carotid diameter (CD, mm) and intima-media thickness (CIMT, mm) was performed at baseline, 3- and 6-months.

Carotid stiffness (CS, m/s) was estimated from aortic pulse pressure (Arteriograph®) and carotid lumen area. Data was analysed by modified intention-to-treat and mixed-model effect, adjusted for confounders.

Results

93 participants had a baseline evaluation; 86% had follow-up data. No statistical interactions occurred between the juice and drug arms. BP was similar between the juices and between the drugs. CIMT was significantly lower following nitrate-containing, compared with placebo juice [−0.06 (95% Confidence Interval −0.12, −0.01), p = 0.022], with no effect on CD. CS reduction was similar between juices [−0.38(−0.67, −0.10) with placebo, −0.13 (−0.42, 0.16) with active juice] and the drugs [−0.30(−0.58, −0.02) with doxazosin, −0.21(−0.51, 0.09), with spironolactone]. No differences were detected between spironolactone or doxazosin on CIMT and CD.

Conclusion

6 months’ intervention with dietary nitrate influences vascular remodelling, but not carotid stiffness or diameter. Neither spironolactone nor doxazosin had a BP-independent effect on carotid structure and function.
STRATEGI PENGEMBANGAN USAHATANI BAWANG MERAH DI KELURAHAN MALUMBI, KECAMATAN KAMBERA, KABUPATEN SUMBA TIMUR
Authors: Wadu Junaedin , Linda Anggreni Madik
Published: December 2020

Penelitian ini bertujuan untuk menganalisis faktor internal dan eksternal serta menetapkan strategi bagi pengembangan usahatani bawang merah di Kelurahan Malumbi, Kecamatan Kambera. Jenis penelitian yang digunakan adalah penelitian eksploratif dengan menggunakan metode survei. Jumlah responden dalam penelitian ini adalah 10 orang. Metode yang digunakan untuk penentuan sampel adalah metode accidential sampling. Data dianalisis dengan menggunakan analisis Internal Factor Evaluation (IFE), External Factor Evaluation, Internal-Eksternal (IE), Matriks Strenghts, Weakness, Opportunities, Treats (SWOT), dan Quantitative Strategic Planning Matrix (QSPM). Hasil penelitian menunjukkan bahwa faktor internal adalah ketersediaan air yang cukup memadai, sistem pemasaran yang tidak efektif. Sedangkan, faktor eksternal adalah permintaan bawang merah tinggi, serta persaingan dan fluktuasi harga jual. Strategi utama pengembangan usahatani bawang merah adalah memperluas lahan usahatani bawang merah dalam rangka meningkatkan kapasitas produksi dan merebut peluang pasar.
ANALISIS PRODUKSI DAN PENDAPATAN PETANI PALA (Myristica fragrans) DI NEGERI HILA, KECAMATAN LEIHITU, KABUPATEN MALUKU TENGAH
Authors: Ridjayanti Risna , Pattiasina Margaretha , Kembauw Esther
Published: December 2020

Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi produksi dan  pendapatan petani pala di Negeri Hila Kecamatan Leihitu Kabupaten Maluku Tengah. responden dipilih dengan menggunakan  metode purposive sampling (sengaja). Alat analisis yang digunakan dalam penelitian ini adalah analisis regresi linear berganda dan analisis pendapatan. Hasil penelitian menunjukkan bahwa modal (X1), luas lahan (X2), penggunaan benih (X3), dan tenaga kerja (X4) berpengaruh nyata secara simultan terhadap produksi pala (Y) dan modal (X1), luas lahan (X2), penggunaan benih (X3), dan tenaga kerja (X4) berpengaruh nyata secara parsial terhadap  produksi pala (Y) di Negeri Hila, Kecamatan Leihitu, Kabupaten Maluku Tengah. Hasil penelitian juga menunjukkan bahwa total pendapatan responden sebesar Rp. 409.990.750,- per tahun dengan rata-rata pendapatan sebesar Rp. 11.080.831,- per tahun.
Manajemen Pembelajaran Berbasis Sekolah di SMK Muhammadiyah 1 Playen Gunungkidul
Authors: Purbadi Purbadi
Published: December 2020

Tujuan penelitian ini adalah untuk mendeskripsikan (1) Manajemen pembelajaran berbasis sekolah di SMK Muhammadiyah 1 Playen Gunungkidul, meliputiperencanaan, pelaksanaan, pengorganisasian, pengwasan/ kontroling, dan evaluasi; (2) faktor-faktor yang mendukung dan menghambat serta solusinya; (3) hasil dalam manajemen pembelajaran berbasis sekolah di SMK Muhammadiyah 1 Playen Gunungkidul. Penelitian ini menggunakan pendekatan kualitatif. Hasil penelitian ini menunjukkan bahwa (1) Manajemen pembelajaran berbasis sekolah di SMK Muhammadiyah 1 Playen Gunungkidul sudah cukup optimal,baik dalam perencanaan, pelaksanaan, pengorganisasian, pengawasan/kontroling, dan evaluasi; (2) faktor-faktor yang mendukung Manajemen pembelajaran berbasis sekolah di SMK Muhammadiyah 1 Playen Gunungkidul meliputi dukungan dari kepala sekolah,guru,karyawan staf TU,komite sekolah,wali murid,siswa,dunia usaha dan dunia industri, rekomendasi dinas Dinas Pendidikan,serta dukungan dari Persyarikatan Muhammadiyah,faktor-faktor yang menghambat Manajemen pembelajaran berbasis sekolah di SMK Muhammadiyah 1 Playen meliputi kurangnya kompetensi guru dalam mengelola pembelajaran,rendahnya kesadaran orang tua terhadap pendidikan anak,dan seringnya pelanggaran yang dilakukan siswaatau indisipliner; (3) Pengelolaan pembelajaran secara optimal di SMK Muhammadiyah 1 Playen Gunungkidul dapat menghasilkan lulusan yang unggul.
Antropologi Politik Helmuth Plessner
Authors: Runesi Yasintus T.
Published: December 2020

In the contexts of contemporary social and political thought, a fundamental anthropological and political problem is thedebate about how deeply the essence of the human related to political praxis. The purpose of this article is to explore the idea ofHelmuth Plessner’s political anthropology as the middle paradigm, between political theology and economic theology. In thefirst and second parts of this article, Plessner’s philosophical anthropology will be presented, which focuses on the concept of theeccentric position of human being. Based on this concept, Plessner attempted to show the mutual interpenetration of philosophyand politics, which will be described in the third part of this article. Plessner insists on the importance of a philosophicalanthropology of the political for practical politics itself. Some conclusion will be drawn concerning the importance of smalldimensions of Plessner’s political anthropology in relation to the current political context.
Inklusivitas Pengelolaan Alokasi Dana Desa (ADD) Berbasis Partisipasi Masyarakat di Desa Air Mata, Kabupaten Kupang
Authors: Pariangu Umbu TW
Published: December 2020

Community participation in the management of village allocation fund in the Village of Mata Air is still far from the requiredstandards. At the planning stage, the management of the fund is deemed as too “technocratic” in which only village elites areinvolved, while the poor segment of the village residents as well as women are not involved. At the implementation stage, thefund management has neither been institutionalized nor determined by the mobilization of government instruments andvillage administrative personnel. So far the community participation only goes in a spontaneous way and as such has reducedthe degree of inclusiveness. As a result, the continuity of villagers’ initiatives is cut off and therefore it does not nurture thesense of belonging in the whole village development. At the supervision level, the fund is controlled in a structural-hierarchicalway without involving the village residents. The residents are not given access to the village fund management. The villagehead, village finance technical executive, and the village treasurer are still considered the most responsible persons in themanagement of village allocation fund.
POPULISME, PILKADA DAN MASA DEPAN DEMOKRASI
Authors: Tan Peter
Published: December 2020

Abstract

Populism has risen to become a contemporary political phenomenon at both the global, national and local levels. Electoral contestations, including the election of district heads or “Pilkada”, were infiltrated by populist political practices. In this paper, I mostly use the perspective of political philosophy on populism. The main thesis of this paper is that populism threatens the existence of democracy when populist actors and politicians exploit the ethnic and religious sentiments of the voters, or exploit the people's vulnerabilities as mere populist narratives and rhetoric to win the electoral support. On the other hand, the discourse on antagonism in left populism is able to make a positive contribution to democracy as long as it is always placed within the framework of an antagonistic democratic discourse. Within the framework of antagonistic democracy, left populism consistently exposes the depravity of power, constructs the “people” as a group that opposes the oligarchic and neoliberal elites, and struggles for the right to social justice of the oppressed. This politico-philosophical analysis of populism is relevant in reflecting on the moments of electoral contestations such as the election of district heads (Pilkada) and on the  fight for a better future of democracy.
Phytoterapy combined with prostate chronic inflammatory diseases and their complications in persons with diabetes mellitus
Authors: І. І. Горпинченко  , Ю. М. Гурженко  , В. В. Спиридоненко
Published: December 2020

The combination in patients with diabetes and chronic prostatitis, demonstrated lower urinary tract symptoms is urgent health and social issue and requires adequate diagnostic measures and medication adjustment. The aim of the study: to determine the long-term application of a combination of phytotherapy in men with lower urinary tract symptoms chronic prostatitis (CP) and diabetes mellitus (DM). Materials and methods. In the -Institute of urology of NAMS of Ukrainewere examined 63 patients with CP on the background of diabetes of 1-St and 2-nd type (mean age of 42.3±0.9 years). In the 1st group patients (n=30) were administered Pravenor 2 capsules per day after meals for 4 months with three 10-day intervals; in the 2nd group (n=33) patients taking the extract of pumpkin seeds ordinary 500 mg 2 times a day for 4 months. Control group (n=32) included almost healthy patients who did not receive treatment during the investigation period. The history of the disease CP amounted to an average of 5.2±0.8 years, SD of 12.8±0.9 years, the ratio of DM 1st / DM 2nd type 70:30%. Results. The use of drugs Pravenor® capsules and suppositories Pravenor was based on long-term medical effects on the inflammatory factor in the tissues of the pancreas. At the control examination one of the most significant indicators was the compensation of carbohydrate metabolism. During the inspection of patients of the 1st group in the control time (30 day) it was found that the use of herbal remedies Pravenor® capsules and suppositories Pravenor® provides a good clinical effect, improve the health and quality of life. Patients 1st clinical group receiving continuous combined therapy and improved almost all the indicators in comparison with the 2nd group. Thus, the maximum flow rate Vmax in patients of the 1st group improved by 24.8%, of urination for IPSS – by 20.6%, QoL – 46.5%, respectively (p<0.05). Patients of the 2nd group of such dynamics have been identified. Conclusion. The use of medicinal herbal remedies Pravenor® capsules and Pravenor suppositories in patients with CP with concomitant DM is a reasonable treatment strategy, contributing to the reduction of dysuric phenomena. The obtained results allow to recommend the use of Pravenor® capsules and suppositories Pravenor for the integrated treatment of patients with chronic pancreatitis on the background of diabetes.
Erectile dysfunction in a progressive mental disorder
Authors: Ю. В. Кукурекін  , В. М. Акулінін  , О. М. Бушученко
Published: December 2020

A study of the nature of sexual disorders in schizophrenia patients, pathogenetic mechanisms of disintegration of the sexual sphere in the presence of a schizophrenic process. The methods of treatment of dis" orders of the copulative function in patients with progressive mental disorders and their efficacy, depending on the particularities of patho" genetic mechanisms of forming sexual disorders.
Experience using selective coagulation nerve branches nervus dorsalis penis in complex therapy premature ejaculation in men
Authors: Ю. М. Гурженко  , Ю. Ю. Синицький
Published: December 2020

The aim of the study: to assess the effectiveness of treatment of premature ejaculation using the minimally invasive method of selective coagulation of the nerve branches n. dorsalis penis (fallonevroramidorzo coagulation) together with the subsequent adaptation therapy. Materials and methods. Under the outpatient and inpatient were examined 343 sexually active men with the syndrome of premature ejaculation. Of them were operated on 172 (50.1 per cent) of the face. The average age of patients amounted to 34.5±2.4 years. Before treatment patients had a diagnosis of premature ejaculation, according to conventional classification they were distributed as follows: еjaculatio praecox relative 91 (52,9%) patients, еjaculatio praecox absoluta 76 (44,2%) and еjaculatio ante portas 5 (2,9%) surveyed. Results. Changes of the clinical picture of the disease in the minimally invasive treatment by means of selective coagulation of the nerve branches n. dorsalis penis (fallonevroramidorzo coagulation) together with the subsequent adaptation of the treatment was analyzed after 3 months. Sex life returned to normal in 143 (82,3%) patients, improved in 18 (10,5%) patients, the clinical efficacy of treatment amounted to 92.5%. 11 (6,4%) patients the improvement is not marked. Conclusion. The use of minimally invasive method of selective coagulation of the nerve branches n. dorsalis penis (fallonevroramidorzo coagulation) together with the subsequent adaptation of therapy in the treatment of premature ejaculation is highly effective. Clinical efficacy amounted to 92.5%. The obtained results allow recommending the use in the treatment of men with premature ejaculation.
Effect of long-term treatment with Kanefron® H on the risk factors of the urinary system, associated with idiopathic calcium urolithiasis
Authors: А. А. Гайбуллаев  , С. С. Кариев
Published: December 2020

Urolithiasis - nephrolithiasis, causes the formation of calculi in the kidneys and efferent urinary ducts due to the substances that form calculi. Idiopathic calcium urolithiasis - the most common form of the disease. Modern herbal medicine can play an important role in primary and secondary prevention of stone formation. Combination Kanefron® herbal drug H (drops: Centaurii herba, 1,8 g / 100 mL; Levistici radix, 1,8 g / 100 mL; Rosmarini folium, 1,8 g / 100 mL; Bionorica SE, Neumarkt / Germany) approved as a drug of vegetable origin. The aim of this study was to investigate risk factors for renal stone formation and activity in patients with idiopathic calcium urolithiasis during long herbal medicine. Thirty-two patients with idiopathic calcium urolithiasis received a daily dose of the drug plant 50 drops three times a day for two months. In another study, 18 patients with similar inclusion criteria were treated for 4 months. In both treatment groups receiving combination herbal preparation contributed to the increase in diuresis and increasing the pH of urine. Within 1 month after treatment, the stone formation (UFL) have improved, which is considered a lower risk. Compared with the 2 = month follow-up in patients who received 4 = monthly treatment, noted a significant improvement in the observed indicators. Adverse events were observed.
Study of the efficacy of the drug Novirin in the treatment of men with HPV infection
Authors: Є. А. Литвинець  , О. О. Козак  , В. Є. Литвинець-Кондрат  , О. В. Кондрат  , А. І. Федорів
Published: December 2020

The aim of the study: to study the efficacy and safety of drug Novirin produced by «Kyiv vitamin factory» and the radio-wave knife for the treatment of men with HPV infection.Materials and methods. Under observation there were 68 patients with genital warts (GW) aged from 19 to 44 years. The duration of the disease was from 1 year to 4 years. Patients were divided into three groups: group 1 received treatment with ostonecrosis drugs; in the 2nd group patients underwent removal GW radio-wave knife; group 3 patients received complex therapy with the use of the drug Novirin and deleting GW radio-wave knife.Results. It is proved that in the 3rd group of patients compared to the 1st and 2nd groups received the most positive results of treatment: a significant decrease in the number of relapses are OK, and no chemical burns to surrounding healthy tissues during treatment.Conclusion. As a result of researches it is established that the use of the drug Novirin and the latest technology radio-wave surgery allows achieving positive clinical results and sustained clinical effect in the treatment of patients with GW. The big advantage of this type of treatment is well tolerated and ease of execution that allows the use of this method in ambulatory practice.
Detection of anti-Hsp60 antibodies in the serum of patients with prostate cancer
Authors: В. М. Григоренко  , Л. Ф. Яковенко  , М. В. Вікарчук  , Р. О. Данилець  , М. О. Косюхно  , І. В. Крупська  , Л. Л. Сидорик
Published: December 2020

A detection of the level of antibodies to heat shock protein Hsp60 in the serum of 55 prostate cancer patients who performed a radical prostatectomy was done. Donor’s blood serum was used as control (n=67). It’s found that the anti-Hsp60 antibodies level were increased in prostate cancer patient’s serum in comparison with the control samples. No consistent correlation was found between the levels of antiHsp60 antibodies and the clinical and morphological characteristics of the tumor (stage, PSA level, Gleason score). It has been found the tendency to increasing of the anti-Hsp60 antibodies level in the patient serum who had the prostate cancer recurrence.
Experience of Furamag usage in postoperative treatment of urological patients
Authors: А. З. Журавчак  , М. П. Мельничук  , М. Д. Дячук
Published: December 2020

еstablising efficacy of Furamag treatment by clinical and laboratory data in operated urological patients
Magnicor is effective and safe domestic drug for prophylaxis of cardiovascular diseases
Authors: А. В. Зайченко  , А. В. Файзуллін
Published: December 2020

Data about pathogenetically justification of use, efficiency and safety of acetylsalicylic acid as antiplatelet agents in cardiology practice are analysed in the article. The article contains short analysis of the domestic market of acetylsalicylic acid preparations, that are used in cardiology practice. The article also contains recommendation of practical character for optimization of choice of acetylsalicylic acid preparations. The authors of the article pay great attention to the analysis of data about influence of medicinal form of acetylsalicylic acid preparations and composition of the combined preparations that contain it on pharmacokinetic parameters and profile of their safety. Based on these data the authors of the article come to the conclusion that one of the most safe and effective preparations of acetylsalicylic acid that is presented today at the market of Ukraine there is Magnicor.
Age characteristics of childhood in terms of flow and physical diagnosis of emergency conditions in primary health care
Authors: Д. А. Шкурупій
Published: December 2020

This paper analyzes the anatomical and functional characteristics of childhood from the prognosis of emergency conditions. Understanding of these characteristics allows to predict and optimize the diagnosis for emergency conditions in children in.
SOLIDIFYING TOURISTS’ POST-TRAVEL MEMORIES THROUGH SOUVENIR
Authors:   Durban University of Technology, Department of Visual Communication Design, Anton Lembede St, Greyville, Durban 4023, South Africa, OLALERE Folasayo E.
Published: December 2020

This paper explores how souvenir can be designed as a means of promoting tourism destinations and experiences. To achieve the research aim, the study first conducted a survey to determine the attributes that influence tourists’ souvenir purchase preferences. A Likert scale questionnaire was used, comprising of questions that cut across the design performance and cultural evaluation indices. The results, which were analysed using descriptive statistics, indicate that the top three attributes that tourists look for in souvenir are features that evoke travel experience, usability and branding with destination features. Based on these findings, experimental research was further conducted to develop a series of souvenir with the attributes embedded. The outcome suggests that the approach could help promote the cultural aspects and also convey the essence of tourism destination to potential visitors.
THE POTENTIAL OF AFRICAN RELIGIOUS PILGRIMAGES AS A TOOL FOR TOURISM DEVELOPMENT IN KWAZULU-NATAL, SOUTH AFRICA
Authors:   University of Zululand, Department of Recreation and Tourism, KwaDlangezwa, South Africa, NOMPUMELELO Linda
Published: December 2020

Religious pilgrimages are components of religious tourism and a revenue generator for different countries. The study aims to explore the contribution of African religious pilgrimages towards tourism development of the study areas. Sequential exploratory mixed method research design was applied in this paper. The study used a convenience sampling method of the non-probability sampling design in selecting 210 respondents. Additionally, convenience sampling was used in selecting 40 participants that were readily and easily accessible in the study area. Lastly, the elucidates that there is a need for tourism development for African religious pilgrimages.
THE EFFECT OF ATTITUDES TOWARD GREEN BEHAVIORS ON GREEN IMAGE, GREEN CUSTOMER SATISFACTION AND GREEN CUSTOMER LOYALTY
Authors:   Bingol University, Management and Organization Department, Bingol, Turkey, ÇAVUSOGLU Sinan , DEMIRAG Bülent ,   Gaziantep University, Department of Property Protection and Security, Gaziantep, Turkey, JUSUF Eddy ,   Universitas Pasundan, Faculty of Engineering, Indonesia, GUNARDI Ardi ,   Universitas Pasundan, Faculty of Economics and Business, Indonesia
Published: December 2020

The research was carried out to determine the effect of attitude towards green behavior on green image, green customer satisfaction and green customer loyalty. The universe of the study consists of customers who have visited green hotels in Turkey. In order to test the hypotheses, Smart PLS 3 (Partial Least Squares) statistics program was used in the research. Bootstrapping technique was used to test the hypotheses that were aimed to be measured in the research. According to the results of the analysis, the attitude towards green behavior is on the green image; the green image has also been found to have a positive effect on green customer satisfaction and green customer loyalty. In addition, as a result of the analysis, it was determined that green customer satisfaction positively affected green customer loyalty.
THE SOCIAL RESPONSIBILITY OF TOURISM AND HOTEL ESTABLISHMENTS AND THEIR ROLE IN SUSTAINABLE TOURISM DEVELOPMENT IN AL-AHSA, SAUDI ARABIA
Authors:   King Faisal University, Department of Social Science, College of Arts, P.O. Box 380, Al Ahsa 31982, Saudi Arabia, e-mail: thassan@kfu.edu.sa Helwan University, Faculty of Tourism and Hotel Management, P.O. Box 12612, Cairo, Egypt, HASSAN Thowayeb H. , SHEHATA Hossam S. ,   King Faisal University, Department of Social Science, College of Arts, P.O. Box 380, Al Ahsa 31982, Saudi Arabia, Alexandria University, Faculty of Tourism and Hotels, P.O. Box21526, Egypt, EL-DIEF Mohammed ,   Umm AL-Qura University, College of Business, Makkah Al Mukramah, Saudi Arabia, Helwan University, Faculty of Tourism and Hotel Management, P.O. Box 12612, Cairo, Egypt, SALEM Amany E. ,   King Faisal University, Department of Social Science, College of Arts, P.O. Box 380, Al Ahsa 31982, Saudi Arabia, e-mail: asalem@kfu.edu.sa Helwan University, Faculty of Tourism and Hotel Management, P.O. Box 12612, Cairo, Egypt
Published: December 2020

This study aims to assess the impact of implementing corporate social responsibility (CSR) practices on sustainable tourism development in Al-Ahsa city, Saudi Arabia. A survey was electronically distributed to the managers of hotels and travel agencies in Al-Ahsa City. A total of eight CSR strategies, including information analysis, compensation, system, delegation, prevention, education, regulation, and marketing, were extracted from the literature, and their effects on overall, economic, ecological, and social sustainability were investigated in hotels and tourism establishments. The results showed that promoting CSR adoption (marketing) and providing sustainability-related educational materials to customers were the most influential CSR practices on sustainability (mean scores±SD were 13.75±1.73 and 12.82±1.98 out of 15, respectively). Sustainable development of hospitality and tourism corporates could be enhanced by implementing marketing and educational CSR practices, which ultimately support the rising trend of sustainable tourism in the Kingdom.
New machine learning based method for identifying objects in biomedical images obtained by photon counting detectors.
Authors:   Kotelnikov Institute of Radioengineering and Electronics of the Russian Academy of Sciences, Mokhovaya 11-7, Moscow, 125009, Russia, Antsiperov V.E.
Published: December 2020

The article discusses a new approach to the problem of recognition, or rather the identification of objects by the shape of their intensity in images formed by photon counting detectors or those close to them. The main problem analyzed within the framework of the approach proposed is related to the quantitative estimation of similarity between the form of radiation intensity of the object in the image and the forms of intensity of previously observed objects (precedents), providing that all of them are given by the registered sets of discrete photocounts (~ photons). It is shown that when the intensity shape is approximated by a mixture of components of an exponential family, for the implementation of the approach proposed in this work a recurrent PM algorithm for estimating the parameters of the intensity shape from a finite sample of counts associated with radiation can be synthesized. The PM algorithm turns out to be a close analogue of the well-known K-means algorithm, which is one of the most popular in the field of machine (statistical) learning. The main features of the method and its implementation are illustrated by the example of applying the method to the problem of image fragments identification for the COVID ‒ CT ‒ Dataset database.
Liability in Russian Corporate Law
Authors: Orlov Vladimir
Published: December 2020

Liability issues related to corporate activities are primarily regulated by general and special rules of the Civil Law in Russia that are mainly dispositive. The general liability rules consist of tort and contract liability provisions of the Civil Code. Special corporate norms are, in turn, included in the Civil Code provisions on juristic persons and legislation regulating corporate forms, and they concern liability of founders, shareholders and corporation as well as executives of corporation. The main form of civil liability is compensation for damages, the award for which generally requires that the illegal action and the caused damages as well as their causal relationship and the fault for causing the damages is proved in accordance with the rules on presumptions and burden of proof provided by the procedural rules. Traditionally, Russian civil liability rules have relied on the concept of illegality of an action (or breach of an obligation) that is to cause liability, which reflects the dominant role of legal supervision in the Russian legal system. However, in the event of liability of corporate executives, a breach of fiduciary duties could be regarded sufficient as a ground to qualify their actions as illegal without particular reference to concrete legal norms. Keywords: Civil liability; Corporation; Corporate executives; Illegality
Features of the visual perception of information and communication object
Authors: Vehter Evgeniya , Efremenko Anastasia , Radchenko Valeria , Shklyar Aleksey
Published: December 2020

This article discusses the basic principles of visual perception of information with objects of sign communication. The features of visual communication, the features of the perception of information, the main criteria and rules for the design of signs of visual communication are highlighted. The article discusses the role of cognitive ergonomics and psychology of perception, as well as the initial set of criteria and techniques that provides an effective and functional process for designing visual communication signs. The main groups of users of children's art schools are considered and options for the design of visual communication for a children's art school are proposed.
Auto-Audit of Digital Earth and Beyond
Authors: Baturin Yuri
Published: December 2020

The question is posed: "If we use the Digital Earth to verify the results of an audit (e.g. land cadastre) conducted in a traditional format, who can verify the Digital Earth itself?" The answer is, "The Digital Earth can audit itself. Only you have to teach it to do it". The mechanism of self-checking is proposed to be realized through autoreflexion. If Digital Earth is "taught" autoreflexion, there are no obstacles to the transition to peer-to-peer reflexion and multirange reflexion. The reflexive model of the Digital Earth is discussed both in the case of ordinary introspection (auto-audit) and in the case of multiple ranks of reflexion. The way of inclusion of the person in the digital network as a support structure of the Digital Earth is discussed. At the next level of development the reflexive Digital Earth becomes recursive, which means development toward the noosphere as understood by academician Vladimir I. Vernadsky – the thinking Digital Earth. Finally, at the highest stage of development Digital Earth will understand man and humanity.
THE INFLUENCE OF MOTIVATION AND DIRECTION FUNCTION ON EMPLOYEE WORK DISCIPLINE IN THE DEPARTMENT OF TOURISM AND CULTURE OF SOUTH OKU DISTRICT
Authors: Margahana Helisia
Published: December 2020

This research study aims to partially and jointly analyze the influence of Motivation, Guidance Function on employee work discipline, and to analyze the most dominant variables in influencing employee work discipline at the Office of Tourism and Culture of South OKU Regency. Results of regression analysis and the correlation between motivation and discipline Employee employment shows a regression model ? = 3.987 + 0.958X1 + e with a correlation coefficient of 0.900. The results of the regression analysis and the correlation between direction on employee work discipline show the regression model ? = 16,805 + 0.665X2 + e with a correlation coefficient of 0.825. The results of multiple regression analysis and the correlation between motivation and direction together on work discipline show the regression model ? = 2.817 + 0.675X1 + 0.300X2 + e with a correlation coefficient of 0.937 at the 95% confidence level, it is found that motivation and direction can simultaneously predict employee work discipline. Motivation and direction simultaneously have a strong positive effect with work discipline of 86.9% and have a significant effect. The effect of motivation and direction simultaneously on the work discipline of the employees of the South OKU Regency Tourism and Culture Office is 2,817, so if there is an increase in motivation and direction together then this will increase the work discipline of the OKU Regency Tourism and Culture Office employees South with significant .. This research was conducted on 28 respondents with the analytical method used is path analysis using SPSS software.
CIVIL SERVICE CANDIDATE TRUST IN GOVERNMENT PERFORMANCE IN IMPLEMENTATION OVERCOMING CORONA VIRUS POLICY IN TANAH LAUT REGENCY
Authors: Mahalayati Bornea Retno , Noveriyadie M. , Sadikin Hanil , Hayat Muzahid Akbar
Published: December 2020

The purpose of this policy communication study was to determine the effect of Mata Najwa's impressions on September 28, 2020, on 17 respondents of CPNS Formation 2019 in Tanah Laut Regency. The focus of the research was determined on the influence of Mata Najwa on the trust of 17 respondents of the 2019 CPNS Formation in Tanah Laut Regency on the performance of the government in dealing with the Corona Virus using the Hypodermic Needle Theory, this theory includes Cognitive Effects, Affective Effects, Behavioral Effects. Policy communication study is a qualitative descriptive study. Data collection was carried out by interview, questionnaire, observation, and documentation. The results of research on 17 2019 CPNS Formation Respondents in Tanah Laut Regency show that there are passive audiences who in different situations can become active audiences. All informants get cognitive effects and affective effects, but on behavioral effects, not all informants experience these effects, but only slightly.
THE IMPORTANCE OF PUBLIC TRUST IN GOVERNMENT POLICIES IN EFFORTS TO ACCELERATE THE MANAGEMENT OF THE COVID 19 PLAGUE
Authors: Hidayat Mahyuni , Wijaya Bambang Adi , Samudro Bayu Lintang , Hayat Muzahid Akbar
Published: December 2020

Corona Virus Disease 2019 (Covid-19) is a pandemic that is being felt by almost all countries, including Indonesia. Apart from having an impact on the safety of people's lives, it also has an impact on the political and economic aspects. There have been many efforts and policies taken by the central and regional governments to date, but it is still felt that they have not given the public hope when this pandemic will end soon. This has the potential to harm public trust (Trust Public) in the performance of the government to handle the covid-19 outbreak. The purpose of this paper is to describe the alternatives that the government should try to do to increase public trust.
IMPACT OF FEMALE SCHOOL TEACHERS’ DRESS CODE ON JOB PERFORMANCES: A CROSS-SECTIONAL STUDY IN SAGA CITY, JAPAN
Authors: Jayasooriya U.G.L.B. , De Silva Saliya , Wanigasundera Wanigasundera Appuhamillage Don Padmasiri
Published: December 2020

The dress is an integral part of a profession. The research focuses on the dress codes of school teachers in Japan. Japan has relaxed the dress norms of school teachers over the years from a traditional/formal dress to a casual dress. We intended to examine if this change has a significant effect on the self-perceived job performance among school teachers in Japan with the purpose of seeking recommendations for many Asian countries like Sri Lanka in which traditional dress norms applied to teachers have not changed much or at all. A combined qualitative and quantitative study was conducted with three chosen prefectural schools in the Saga city, Japan. The qualitative study was a thematic analysis based on in-depth interviews with five selected school teachers. The quantitative study (n=30) was a descriptive cross-sectional study. A culturally validated, self-administered questionnaire was used to collect data on socio- demographic characteristics and dress code from the study sample. Self-perceived comfort level and effect of the dress code on performing their jobs were assessed on a set of given scenarios related to their profession. The responses were recorded on a five-point Likert scale. The subjects aged from 26 to 61 years old (mean =44±8 years).  Wilcoxon Signed- Rank test indicated that the self-reported mean comfort score for casual dress of 25.75 is significantly higher than that of Kimono (mean score =10.77, p=.000). Most respondents believed that their job performance could be affected by the way they dress. According to the in-depth interviews, it was revealed that, compared to the traditional Kimono, the casual dress is convenient and comfortable for the duties they perform.  Thus, the study reveals that Japan sets an example for the countries that are more concerned about embodying cultural symbols in the appearance of teachers rather than their convenience and efficiency: Japan has been successful in relaxing dress norms while sustaining the quality of education and cultural values.
Effects of stifled cooking on the quality and lipid-lowering potential of oils extracted from two species of pumpkin seeds (Citrullus lanatus and Cucumeropsis mannii)
Authors: Nameni Rosine O. , Woumbo Cerile Y. , Kengne Anne P. N. , Zokou Ronice , Tekou Florian A. , Nguekouo Philippe T. , Dongmo Patrick F. , Kuate Dieudonne
Published: December 2020

Abstract Background: Hyperlipidemia is a major risk factor for cardiovascular diseases. Cucumeropsis mannii and Citrullus lanatus commonly called pumpkin seeds or egussi, the oil-rich seeds, have already demonstrated hypolipidemic activity. In Africa, these seeds are popularly used in the preparation of local foods. During that thermal process, the fatty acid content of pumpkin seeds’ oils may be altered in their functionality. Thus, this work aims at studying the effect of stifled cooking on the quality and the lipid-lowering potential of oils’ extracts from Citrullus lanatus (CL) and Cucumeropsis mannii (CM). Methods: The oils were extracted from the pumpkin seeds (raw and cooked) by a mixture of chloroform and methanol (2/1). The acid, iodine, peroxide and thiobarbituric acid value of the oils were assessed. For 28 days, the oils were subsequently administered by oral intubation to high-fat diet induced hyperlipidemic rats. At the end of the experimentation, the lipid profile, the markers of the hepatic and kidney function were determined. Results: The oils extracted from raw CL and CM significantly reduced (p˂0,05) serum triglyceride, total cholesterol, Low Density Lipoprotein (LDL) cholesterol, uric acid, serum transaminases, creatinine, urea and increases the serum High Density Lipoprotein (HDL)cholesterol level relative to the oils extracted from cooked CM and CL. Moreover, the oil from cooked CL significantly (p<0.05) reduced some lipid profile and toxicity parameters (triglycerides and Alanine animotransferase) while increasing the serum HDL compared to the oil extracted from cooked CM. On the other hand, all the quality parameters of the raw materials followed the limits for vegetable oils, as opposed to cooked samples. Conclusion: Stifled cooking affects the lipid-lowering potential of CM oil compared to that of CL oil. Keywords: Citrullus lanatus; Cucumeropsis mannii; Cucurbitaceae, Hyperlipidemia, Stifled cooking.
The Strategy to Build Educative Interaction in Islamic Education on Online Learning Setting
Authors: Zebua Rony Sandra Yofa
Published: December 2020

Nowadays, online learning has forced educational stakeholders to sufficiently involve online learning by handling the fundamental difference from traditional learning platforms. While educative interaction is vital but very limited to online learning, the teachers should condition the new environment to enable the learning process. However, educative interaction on online learning requires exact syntax to help the teachers implement it correctly. Therefore, this study aimed to identify the implementation of educative learning on online learning and formulate the syntax to help teachers create educative interaction. The study focused on Islamic and Character Education subjects. The research method is qualitative, using in-depth interviews to gather the data. The informants were from 2 different elementary schools. The study result revealed two types of syntax for educative interaction on online learning: the syntax of educative interaction on real-time chatting app and syntax of educative interaction on the video conference app. Every syntax has similar general phases: preparation, introduction, core, and closing. However, every phase has different details, adjusted to the service provided by the application used. Eventually, the teachers' competence and spirit and supporting infrastructure become the primary factors in maximizing the interaction. Besides, application choice determines the strategy that will be done.
BNT162b2 Vaccine: possible codons misreading, errors in protein synthesis and alternative splicing's anomalies
Authors: Smith Kira
Published: December 2020

BNT162b2 vaccine against Covid-19 is composed of an RNA having 4284 nucleotides, divided into 6 sections, which bring the information to create a factory of S Spike proteins, the ones used by Sars-CoV-2 (Covid-19) to infect the host. After that, these proteins are directed outside the cell, triggering the immune reaction and antibody production.The problem is the heavy alteration of the mRNA: Uracil is replaced to fool the immune system with Ψ (Pseudouridine); the letters of all codon triplets are replaced by a C or a G, to extremely increase the speed of protein synthesis; replacement of some amino acids with Proline; addition of a sequence (3'-UTR) with unknown alteration. These impairments could cause strong doubts about the presence of codon usage errors. An eventual mistranslation has consequences on the pathophysiology of a variety of diseases.In addition, mRNA injected is a pre-mRNA, which can lead to the multiple mature mRNAs; these are alternative splicing anomalies, direct source of serious long-term harm on the human health.In essence, what will be created may not be identical with protein S Spike: just an error in translational decoding, codons misreading, production of different amino acids, then proteins, to cause serious long-term damage to human health, despite the DNA is not modified, being instead in the cell nucleus and not in the cytoplasm, where the modified mRNA arrives.However, in this case, the correlation between speed of synthesis and protein expression with synthesis errors, as well as the mechanism that could affect the translation of the sequence remain obscure, many trials have not yet been performed.
Hay không hay nhất
Authors: Khuc Quy Van
Published: December 2020

Hay không hay nhất. Hay không hay nhất. Hay không hay nhất
Pentingnya Materi Lingkungan dalam Pembelajaran Bahasa Indonesia di Lingkungan Sekolah
Authors: izzah Rahmil
Published: December 2020

Esai ini dibuat untuk mengetahui Pentingnya Materi Lingkungan dalam Pembelajaran Bahasa Indonesia di Lingkungan Sekolah karena Materi lingkungan di dalam pembelajaran bahasa Indonesia menjadi salah satu topic penting yang perlu dibahas karena pada dasarnya lingkungan menjadi topik yang sebagian besar memenuhi buku teks pembelajaran Bahasa Indonesia. Di dalam pembelajaran bahasa Indonesia, materi lingkungan yang biasanya dibahas yaitu mengenai lingkungan sekitar yang ada di masyarakat. Pada penelitian yang saya lakukan terhadap pembelajaran bahasa Indonesia jugalah yang menjadikan materi lingkungan sebagai tema atau topic yang perlu ditelaah, dianalisis dan harus dipahami oleh peserta didik atau siswa di sekolah.
Merefleksi Kembali Buku Berkonten Misteri
Authors: Firdiansyah Deski
Published: December 2020

Buku ini memberikan gambaran yang cukup terang dan boleh dikatakan kesimpulan (conclusion) terhadap beberapa “misteri besar dunia” yang sampai sekarang belum terungkap. Di samping menyajikan kesimpulan terhadap tokoh-tokoh yang diangkat, buku ini juga menyajikan berbagai referensi mengenai informasi sejarah maupun informasi terkait lainnya dari setiap tokoh. Hal itulah yang membuat buku ini semakin menarik dan selalu asyik untuk diikuti dari awal sampai akhir.
Swipe kinematic differences in young children with autism spectrum disorders are task- and age-dependent: A smart tablet game approach
Authors: Lu Szu-Ching , Rowe Philip , Tachtatzis Christos , Andonovic Ivan , Anzulewicz Anna , Sobota Krzysztof , Delafield-Butt Jonathan
Published: December 2020

The motor system is becoming increasingly recognized as an important site of disruptions in autism spectrum disorders (ASD). However, the precise nature of this motor disruption remains unclear with some conflicted reports between papers. A bottleneck in kinematic studies of children with ASD has been the use of laboratory-based motion tracking systems and experimental paradigms that require didactic instructions. Thus, we employed an attractive smart tablet gameplay methodology to engage children’s interest without complicated verbal instruction. Children’s movements on the touch screen were recorded as they engaged in gameplay of their own volition, enabling improved ecological validity in data capture. Swipe kinematics were computed from two games that afforded goal-directed and free-style scribbling, respectively. 82 children aged 2-6 years were tested, including 37 children with ASD and 45 typically developing (TD) children. Kinematic analyses revealed significant age, group, and task differences. In comparison to aged-matched TD children, children with ASD under 5 years old performed faster goal-directed movements, whereas those over 5 years old performed slower goal-directed movements. In contrast, children with ASD moved faster than TD children irrespective of age during creative scribbling. Interestingly, movement speed increased with age in TD children in both game contexts, likely due to motor skill and confidence development, but this was not true for children with ASD, who moved slower in the case of goal-directed swipes or with no difference in the case of creative scribbling. These findings support emerging evidence for differences in maturation of visuomotor integration in preschool children with ASD.
Evidence for Neuropsychological Health Disparities in Black Americans with HIV Disease
Authors: Thompson Jennifer L. , Beltran-Najera Ilex , Johnson Briana , Morales Yenifer , Woods Steven Paul
Published: December 2020

Objective: Black Americans are at high risk for HIV disease and associated morbidity. However, we know little about the neuropsychological impact and correlates of HIV disease among Black Americans. Methods: Participants included 40 Black persons with HIV (PWH), 83 White PWH, 28 Black HIV- and 64 White HIV- individuals. Neurocognition was measured with raw, sample-based z-scores from a clinical battery. Everyday functioning was assessed using self- and clinician-rated measures of cognitive symptoms and activities of daily living. HIV-associated neurocognitive disorders were classified using the Frascati criteria. Results: We observed a significant three-way interaction between HIV, race, and domain on neurocognitive z-scores. This omnibus effect was driven by large effect size decrements in semantic memory and processing speed in Black PWH compared to the other groups. Black PWH participants also demonstrated higher frequencies of HIV-associated neurocognitive disorders as compared to White PWH. Unexpectedly, global neurocognition was negatively related to everyday functioning for White PWH, but not for Black PWH. Conclusions: Systemic disadvantages for Black Americans may combine with HIV disease to compound some neurocognitive impairments in this vulnerable population. Prospective studies are needed to identify better ways to prevent and manage HIV-associated neurocognitive disorders among Black Americans.