bluuebunny/crossref_metadata_2025 huggingface dataset:
CLOUD SECURITY: A REVIEW OF CURRENT ISSUES AND PROPOSED SOLUTIONS
Authors:   Azerbaijan State Oil and Industry University, Ismayilov Elviz
Published: October 2022

Cloud technologies are currently one of the fastest growing directions in the IT field. This architecture uses virtualization technology in several computing paradigms (distributed systems, grid and service computing, etc.). It is possible to reach the goal using the unlimited possibilities of the Internet. It should be noted that most companies have transferred their resources and capabilities to cloud technology. According to Check Point Software Technologies Ltd 2020 statistics, 39% of enterprises said that security is important in cloud technology, and 52% said that public and hybrid cloud technologies have become more critical in the direction of security over the past two years. Enterprises are concerned about personal data storage and using special software enabled by cloud technologies. They are considering these points. This paper also discusses the various benefits of the cloud with its challenges and applications
A COMPARATIVE ASSESSMENT OF MACHINE LEARNING MODELS FOR PREDICTING WIND SPEED
Authors:   North Tehran Branch Azad University, Gholamrezaie Faezeh , Hosseini Arash ,   Shahed University,   Azerbaijan State Oil and Industry University, Ismayilova Nigar
Published: October 2022

Renewable energy is one of the most critical issues of continuously increasing electricity consumption which is becoming a desirable alternative to traditional methods of electricity generation such as coal or fossil fuels. This study aimed to develop, evaluate, and compare the performance of Linear multiple regression (MLR), support vector regression (SVR), Bagging and random forest (R.F.), and decision tree (CART) models in predicting wind speed in Southeastern Iran. The data used in this research is related to the statistics of 10 minutes of wind speed in 10-meter, 30-meter, and 40-meter wind turbines, the standard deviation of wind speed, air temperature, humidity, and amount of the Sun's radiation. The bagging and random forest model with an RMSE error of 0.0086 perform better than others in this dataset, while the MLR model with an RMSE error of 0.0407 has the worst.
The Association Between Cognition of Obstructive Sleep Apnea Patients and Urinary AD7c-NTP Level: Investigation and Application
Authors: Guo Yumiao , Kang Meimei , Hui Xinjie , Fan Xiaojun , Zhang Lianguo , Wang Yejun , Wang Rong , Nie Xiuhong
Published: October 2022

Background: Obstructive sleep apnea (OSA) is a multi-component disorder, which has many comorbidities, including cognitive impairment. Although its potential risk factors were unknown, they could affect the patient’s quality of life and long-term prognosis. Objective: The purpose of this study was to investigate the application of urinary Alzheimer’s disease-associated neurofilament protein (AD7c-NTP) levels in the assessment of cognitive impairment in OSA patients, and to analyze the predictive value of potential high-risk factors on cognitive impairment in OSA patients. Methods: 138 young and middle-aged adults were recruited and underwent overnight polysomnographic recording, Montreal Cognitive Assessment (MoCA), and urinary AD7c-NTP test. AD7c-NTP and other factors were further applied as biomarkers to develop a cognition risk prediction model. Results: Compared with the control, OSA patients showed significantly lower MoCA scores and higher urinary AD7c-NTP concentrations, while the severe OSA group appeared more significant. The urinary AD7c-NTP level of the OSA cognitive impairment group was higher than that of the non-cognitive impairment group. The results of regression analysis showed that urinary AD7c-NTP level was an independent predictor of cognitive impairment in OSA patients. Based on urinary AD7c-NTP levels and other selected factors, a multimodal prediction model for assessing the risk of cognitive impairment in OSA patients was initially established. Conclusion: The increased urinary AD7c-NTP level could be used as a relevant peripheral biomarker of cognitive impairment in OSA patients. A model using urinary AD7c-NTP combined with other factors was developed and could accurately assess the cognition risk of OSA patients.
Natural language processing (NLP) aided qualitative method in health research
Authors: Cheligeer Cheligeer , Yang Lin , Nandi Tannistha , Doktorchik Chelsea , Quan Hude , Zeng Yong , Singh Shaminder
Published: October 2022

Qualitative data analysis is produced frequently in healthcare settings, which is a time-consuming and skilled analytic task. The use of qualitative research findings in clinical settings takes years, which is sometimes obsolete knowledge as the health context is dynamic. Artificial Intelligence (AI)-based qualitative data analysis might present with rapid analysis of text-based data in real-time, thereby empowering qualitative researchers to expedite their analysis and facilitate timely use of the research findings. We tested an AI-based method to complement the manual analysis of text-based data from the verbatim transcripts of seven mall managers’ interviews. First, we prepared text data into a machine-calculable format and employed BERT model to extract sentence-level features in our case. Second, we implement TF-IDF-based keywords mining techniques to extract the main candidate themes from the interview transcripts to support text-based analysis, including: 1) primary cluster detection algorithm, and 2) keyword extraction algorithm. The extracted core themes provide qualitative researchers with a more comprehensive overview of the qualitative data. Most of the sentences clustered in meaningful short topics or sentences carrying independent and clear information. The extracted topics and clustered sentences reduced qualitative researchers’ workload by condensing and identifying meaningful concepts and naming them. This method combining contextualized word embeddings, unsupervised clustering, and keyword extraction techniques can significantly reduce the overall workload and time consumed in qualitative research using conventional methods.
Consequences of Neglecting Epidemiology by Global Polio Eradication Initiative
Authors: John T Jacob , Dharmapalan Dhanya
Published: October 2022

Global Polio Eradication Initiative (GPEI) was assigned the task of eliminating polio in low income countries in Africa and Asia. GPEI did not apply epidemiological guidance in designing vaccination tactics while aiming to achieve the laudable goal of ‘no child ever should get polio paralysis’. The force of infection of polio was even higher than that of measles, evidenced by its younger age distribution. Epidemiology taught that a vaccine of very high vaccine efficacy (VE) was required to prevent polio in vaccinated infants. GPEI chose to use trivalent oral polio vaccine (tOPV) exclusively (ignoring its very low VE in low income countries of Africa and Asia), instead of inactivated poliovirus vaccine (IPV) that has very high VE. The reasons were ease of giving and low cost. While every epidemiological observation pointed to respiratory transmission of wild polioviruses, GPEI maintained it was faecal-oral, ostensibly to justify the promotion of OPV.

Consequently, eradication of poliovirus type 1 is yet to be achieved; type 3 was eradicated 12 years beyond target; only type 2 could be eradicated before the set target year of 2000. These delays could have been avoided by using IPV (with or without OPV).

When using vaccines, not only VE but also safety had to be assured. GPEI ignored the safety problems of OPV. During the last 22 years vaccine-virus has caused polio outbreaks in 34 countries, the epidemiological warnings of which had been ignored by GPEI. Vaccine viruses are genetically unstable and regain virulence and transmission efficiency – the two properties that were minimised by attenuation. The many thousands of children paralysed by vaccine viruses remind the promoters and donors of GPEI that their goal ought to be that every child is hereafter protected from polio by giving just 3 doses of IPV.
Incorporating ‘Effort’ into Communication Models: An Exploratory Study
Authors: Rausch Anthony
Published: October 2022

This paper proposes that _effort_ must be taken into account in both theorization and assessments of communication and, accordingly, offers an exploratory consideration of effort in communication encounters. As a subjective element of communication, operationalizing effort in communication encounters is very difficult. As a result, there has been very little research taking up effort as a factor in communication. The present research proposes that effort be viewed in communication as one element to be contrasted with others. In this research, effort is cast as one of four communication encounter success factors, along with topic knowledge, communication skill and comfortable communication. As a means of preliminarily testing the proposition, research participants were asked to assess these four factors—effort, knowledge, skill and cordiality—both for themselves and for the other in their communication interaction and as reflective of success in a professional communication encounter (or not) or satisfaction with a personal communication encounter (or not). The research tentatively points toward effort as a meaningful construct in interpersonal communication studies, with indication of several identifiable patterns. However, as preliminary research, the paper concludes by noting that the concepts must be more clearly delineated and the methodology and tools more robustly designed.
Monopsony and Gender Wage Discrimination in the Philippines
Authors: Lanzona, Jr. Leonardo A.
Published: October 2022

Based on a selection bias corrected model using a multinomial logit, the study estimated wage elasticities of labor supply between men and women to measure the degree of monopsony in a less developed economy. Data from pooled Philippine Labor Force Surveys show a greater tendency for women to not be involved in local labor markets and not as engaged as men in alternative work arrangements. While monopsony is detected in both male and female labor markets, the degree of the market imperfections is greater in the latter as wage elasticity is not significantly different from zero for women. Women tended to be less mobile in shifting to labor market arrangements, and a negative self-selection bias is found in the wages of women engaged in permanent labor arrangements.
Regression dependence between the falling number of the gluten-free flour mixture and composition of the components
Authors:   Kuban State Technological University, Shmalko N. A. , Nikitin I. A. ,   K.G. Razumovsky Moscow State University of technologies and management
Published: October 2022

Modern technologies for the production of gluten-free flour products founded on flour mixtures are based on the processing of raw materials of plant origin, mainly flour with a high content of starch polysaccharides. A wide range of gluten-free bakery mixes has been developed, formulations for semi-finished and finished products have been designed by optimizing the chemical composition and nutritional value. The solution of the technological problem provides for multidimensional modeling of the relationship of a certain tightness between the studied quantitative characteristics by means of regression analysis. The regression dependence was studied using computer statistical analysis in the STATICTICA program by obtaining a Piece linear regression model with user-defined break-point. The break point (250 s) corresponded to the lower limit of the falling number for baking flour with normal autolytic activity. Regression analysis of the falling number of a gluten-free flour mixture with a break point made it possible to obtain two analytical linear dependencies for predicting the parameter values in separate areas up to the break point of the function. The constructed regression model is distinguished by high prediction accuracy (the multiple correlation coefficient R = 0,99981) and adequacy when the model residuals correspond to a normal distribution. The optimal amount of components in a gluten-free flour mixture with nor-mal autolytic activity (at 330 c in the experiment) was 20 % CMGP and 80 % ACM.
Use of plant raw materials in the technology of flour confectionery products
Authors:   Kazan National Research Technological University, Borisova S. W. , Mingaleeva Z. Sh. ,   Kazan National Research Technological University, Muhammatchina N. U. ,   Kazan National Research Technological University, Starovoitova O. V. ,   Kazan National Research Technological University, Sagdeeva G. S. ,   Nizhnekamsk Chemical-Technological Institute
Published: October 2022

The article presents the results of using coconut sugar and coconut oil in the recipe for making cupcakes. The organoleptic and physico-chemical parameters (humidity, acidity, wetness, specific volume and density) of finished products prepared using coconut sugar and coconut oil were studied. The consumer properties of cupcakes during storage are determined.
STRATEGI PEMASARAN PT SANGHIANG PERKASA DALAM MENINGKATKAN PENJUALAN PRODUK
Authors: Nugroho Muhammad Awal Satrio , Istriana Istriana
Published: October 2022

Persaingan adalah hal yang sangat penting bagi keberhasilan atau kegagalan perusahaan. Persaingan perusahaan untuk berprestasi atau mencapai kinerja yang tinggi dengan menerapkan strategi, bertujuan mencapai posisi yang menguntungkan dan kuat untuk membendung persaingan dalam industri. PT. Sanghiang Perkasa (Kalbe Nutritionals). Pada masa pandemi saat ini perusahaan PT. Sanghiang Perkasa (Kalbe Nutritionals) Yogyakarta sedang merencanakan strategi agar mampu bertahan dalam menghadapi persaingan dengan pelaku bisnis yang lain dan mampu meningkatkan penjualan produk. Untuk mengetahui strategi pemasaran PT Sanghiang Perkasa dalam meningkatkan penjualan Produk. Penelitian ini menggunakan jenis penelitian kualitatif yang bersifat deskriptif. Teknik pengumpulan data menggunakan wawancara, observasi dan dokumentasi. Pada penelitian ini analisis dilakukan dengan cara mendeskripsikan strategi pemasaran pemasaran PT Sanghiang Perkasa dalam Meningkatkan Penjualan Produk. Posisi strategi keberlanjutan usaha PT Sanghiang Perkasa melalui analisis SWOT berada pada kuadran I, dengan kekuatan sebesar 0,5 (5%) dan peluang sebesar 0,4 (4%). Hal ini menunjukkan bahwa kekuatan dan peluang masih dibawah 50%, artinya PT Sanghiang Perkasa memiliki kekuatan dan peluang namun berada dititik rendah sehingga membutuhkan alternatif strategi untuk PT Sanghiang Perkasa jangka menengah strategi SO. Strategi yang bisa diterapkan antara lain strategi Strenghts Opportunities (SO) dengan memaksimalkan kekuatan yang dimiliki dan memperhatikan peluang pasar. Alternatif strategi yang dapat diterapkan oleh PT Sanghiang Perkasa setelah mengetahui posisi pemasaran usaha yang dimilikinya yaitu dengan mempertahankan dan meningkatkan kualitas produk dan layanan kepada konsumen. Meningkatnya penjualan PT. Sanghiang Perkasa mengindikasikan adanya kinerja pemasaran yang baik, dan tentunya sangat berpengaruh positif bagi kelangsungan hidup perusahaan.
PENGARUH STRES KERJA DAN KEPUASAN KERJA TERHADAP KINERJA GURU SMA NEGERI 1 PUNDONG
Authors: Nurwahyudi Muhammad Robi , Astuti Dwi
Published: October 2022

Penelitian ini bertujuan untuk mengetahui pengaruh stres kerja dan kepuasan kerja terhadap kinerja guru SMA Negeri 1 Pundong. Penelitian ini menggunakan pendekatan kuantitatif. Sampel dalam penelitian ini adalah seluruh populasi guru SMA Negeri 1 Pundong yang berjumlah 40 guru. Pengumpulan data menggunakan kuesioner. Teknik analisis data yang digunakan dalam penelitian ini adalah analisis regresi berganda dengan menggunakan software SPSS versi 25.

Hasil penelitian ini menunjukkan bahwa stres kerja dan kepuasan kerja secara bersama-sama memiliki pengaruh yang signifikan terhadap kinerja guru ditunjukkan dengan f hitung (24,833) > f tabel (3,25) dengan taraf signifikansi 0,000 < 0,05. Demikian pula dengan Uji T (Parsial) untuk variabel kepuasan kerja (X2) berpengaruh positif dan signifikan terhadap kinerja guru diperoleh nilai t hitung (5,146) > t tabel (2,026) dengan taraf signifikansi 0,000 < 0,05, akan tetapi terdapat variabel stres kerja (X1) yang tidak berpengaruh negatif dan signifikan terhadap kinerja guru diperoleh nilai t hitung (1,995) < t tabel (2,026) dengan taraf signifikansi 0,053 > 0,05. Sedangkan besarnya hubungan stres kerja dan kepuasan kerja terhadap guru diperoleh nilai R2 sebesar 0,573 atau 57,3% sedangkan sisanya 42,7% dipengaruhi oleh variabel lain yang tidak dimasukkan dalam penelitian ini.
PENGARUH MONITORING, MOTIVASI DAN EVALUASI KINERJA TERHADAP PRODUKTIVITAS KARYAWAN PADA THE RICH JOGJA HOTEL
Authors: Damayanti Dila , Pamungkas Andre Bayu
Published: October 2022

Penelitian ini bertujuan untuk mengetahui pengaruh monitoring, motivasi, dan evaluasi kinerja terhadap produktivitas karyawan pada The Rich Jogja Hotel Mlati Sleman, Yogyakarta. Sampel dalam penelitian ini berjumlah 40 orang yang diperoleh dengan teknik purposive sampling, Data hasil isian kuisioner yang disebar melalui Google form lalu diuji validitasnya dan realibilitasnya, Teknik analisis data menggunakan regresi linier berganda menggunakan perangkat lunak SPSS versi 22.

Hasil penelitian ini menunjukan bahwa secara keseluruhan ketiga variabel memiliki pengaruh terhadap produktivitas karyawan, ditunjukan dari hasil uji secara parsial yang hasilnya dari setiap variable memiliki hasil thitung lebih besar dari nilai t-tabel (1,68709), dan uji F diperoleh hasil Fhitung sebesar 8,98. Berdasarkan hasil tersebut peneliti menyimpulkan bahwa nilai Fhitung lebih besar Ftabel, (8,98>1,98) pada taraf signifikansi 5%. Hal tersebut menunjukan bahwa monitoring, motivasi dan evaluasi kinerja terdapat pengaruh yang positif signifikan terhadap produktivitas karyawan.
Benefícios e Segurança dos Exercícios Físicos em Pacientes com Metástases Ósseas: Revisão Sistemática da Literatura e Metanálise
Authors: Siiss Letícia Antoniolli , Guarda Amanda , Graeff Daniela Bertol , Cecagno-Zanini Sheila Cristina
Published: October 2022

Introdução: A expectativa de vida de pessoas com câncer metastático está aumentando, mas esse grupo de pacientes corre um risco considerável de apresentar problemas psicológicos e de saúde física. Nesse sentido, o exercício físico tem sido um aliado no tratamento de pacientes com metástases ósseas. Objetivo: Realizar uma revisão sistemática e metanálise sobre a segurança e os benefícios do exercício físico em pacientes com metástases ósseas. Método: Metanálise com pesquisa bibliográfica realizada nas bases eletrônicas: PubMed, LILACS, PEDro e Embase. Resultados: Dos 396 estudos, somente dez foram incluídos, com um total de 531 indivíduos. Não foi observado nenhum efeito adverso musculoesquelético durante a intervenção, sendo significativamente seguro o exercício em indivíduos com metástases ósseas. Não houve melhora considerável na capacidade aeróbica, progressão da doença, qualidade de vida, massa magra e gordura corporal. Três dos estudos incluídos avaliaram a dor durante e após a intervenção, demonstrando melhora no escore de dor, assim como a diminuição do uso do analgésico no grupo intervenção. Conclusão: A terapia com exercícios aeróbicos e isométricos e segura para pacientes com metástases ósseas, além de apresentar melhora da dor, mas sem evolução relevante na capacidade aeróbica, na progressão da doença, na massa corporal e na qualidade de vida.
THE MOLECULAR MECHANISM OF PYROPTOSIS AND ITS RELATED DISEASES
Authors: Касяненко Оксана Іванівна , Люй Мінченг
Published: October 2022

Cells are the basic unit of life, and cell death plays an important role in the body’s metabolism, the occurrence and development of diseases. Pyroptosis is a form of programmed cell death. Pyroptosis is significantly different from other cell death methods (such as apoptosis, necrosis, etc.) in morphological characteristics, occurrence mechanism, and mechanism of action. When a cell undergoes pyroptosis, the nucleus condenses to form a pyroptotic body, numerous pores appear in the cell membrane, the cell swells and ruptures, releasing its contents. Caspase family is a homologous and structurally similar proteolytic enzyme in cytoplasm, which selectively recognizes and cleaves peptide bonds behind downstream target aspartic acid residues. Canspase 1,4,5,11 can induce pyroptosis through different pathways. Besides caspases, gasdermin also plays an important role in pyroptosis. Gasdermins (GSDMs) are a family of functionally diverse proteins expressed in a variety of cell types and tissues. The Gasdermin family includes 6 members, of which gasdermin D is the executor of pyroptosis. Upon cleavage by activated capsese, gasdermen D can be divided into N and C segments. Among them, the N fragment can form pores in the cell membrane, leading to cell swelling, rupture, outflow of cytokines and other contents, triggering the body’s immune response, and leading to pyroptosis. The occurrence of pyroptosis can be divided into the classical pathway and the non-classical pathway. The classical pathway mainly depends on caspase-1, while the non-canonical pathway depends on the activation of Caspase-4/5/11. In addition, there are uncommon Caspase-3/8- mediated pathway and Granzyme-mediated pathway. As a way of cell death, pyroptosis is inextricably linked to disease. Inflammasomes and cytokines produced in the process of pyroptosis can trigger an inflammatory response in the body, and an excessive inflammatory response can lead to diseases, such as infectious diseases, neurological diseases, and tumors. In infectious diseases, pyroptosis is closely related to the infection of a variety of bacteria, fungi and viruses, and PAMPs and LPS can be recognized by corresponding inflammasomes and caspases, respectively, and activate the downstream pyroptotic pathways. Pathogen infection is the main way to induce pyroptosis. In cardiovascular diseases, a high-fat environment can induce an increase in reactive oxygen species (ROS), trigger endothelial cell pyroptosis, and exacerbate the development of atherosclerosis (AS). In the nervous system, cell death is involved in the pathogenesis of the progression of degenerative diseases of the central nervous system, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and stroke. In terms of tumors, pyroptosis can inhibit the occurrence and development of tumors, and at the same time, as a pro-inflammatory death, pyroptosis can form a microenvironment suitable for tumor cell growth, thereby promoting tumor growth.
ВИЗНАЧЕННЯ АНТАГОНІСТИЧНОЇ АКТИВНОСТІ ПРОБІОТИЧНОГО ПРЕПАРАТУ «БІОЗАПІН»
Authors: Чечет Ольга Миколаївна , Коваленко Вячеслав Леонідович , Горбатюк Ольга Іванівна , Гайдей Ольга Сергіївна , Кравцова Оксана Леонідівна , Андріящук Валентина Олександрівна , Мусієць Ірина Володимирівна , Ординська Діана Олександрівна
Published: October 2022

За сучасного розвитку птахівництва пріоритетним є органічне ведення галузі. Тому питання забезпечення епізоотичного благополуччя птиці потребують глибокого вивчення і корекції в нових умовах господарювання. За даними вчених, особливо це стало актуальним після впровадження новітніх енергозберігаючих технологій та прийняття інноваційних рішень щодо утримання та годівлі птиці, пріоритетним із яких є корекція біоценозів шлунково-кишкового тракту птиці. Найбільш економічно вигідним є застосування препаратів на основі речовин природного походження, якими є новітні пробіотики, одержані на основі представників нормальної коменсальної мікрофлори. Тому, інтерес до пробіотиків, в т.ч. на основі Bacillus subtilis, пов’язаний із можливістю впливу на формування нормофлори шлунково-кишкового тракту птиці, підтриманні її сталого балансу та біобезпеки навколишнього середовища, в якому вона перебуває. Розроблений нами новий пробіотик «Біозапін», складовими компонентами якого є бактерії Bacillus subtilis і Bacillus amiljliquefaciens, здатний забезпечувати означені вимоги. Метою роботи було дослідити антагоністичну активність нового пробіотику «Біозапін» за його взаємодії з грамнегативними та грампозитивними тестовими бактеріями «in vitro». Випробування пробіотику «Біозапін» проведено двома методами – методом відтермінованого антагонізму та методом блоків з триразовими повторюваностями дослідів. За виконання обох методів в якості індикаторів використані тестові мікроорганізми Pseudomonas aeruginosa АТСС 15442, Escherichia coli АТСС 25922, Salmonella typhimurium АТСС 29630 та Staphylococcus aureus АТСС 6538. Облік результатів проведено за величиною діаметрів зон пригнічення росту тестових культур мікроорганізмів. Аналіз результатів випробувань пробіотику «Бозапін», за використання означених методів, показав ефективну антагоністичну активність препарату за його взаємодії з тестовими культурами грампозитивних і грамнегативних бактерій. Доведено методом відтермінованого антагонізму та методом блоків дуже високий та високий рівні антагоністичної активності пробіотичного препарату «Біозапін» щодо дії на тестові бактерії, зокрема на Escherichia coli АТСС 25922 з діаметрами зон інгібування росту 39,1±0,13 і 35,8±0,13 мм відповідно до методу; Pseudomonas aeruginosa АТСС 15442 – 30,1±0,07 і 31,5±0,87; Salmonella typhimurium АТСС 29630 – 37,3±0,27 і 36,7±0,13 і Staphylococcus aureus АТСС 6538 – 38,9±0,07 і 37,7±0,13 аналогічно. Перспективність застосування пробіотику «Біозапін» у сучасному птахівництві полягає у підтриманні біологічним способом стабільної епізоотичної ситуації щодо бактеріальних інфекцій серед птиці та правильному формуванню мікробіоценозу у шлунково-кишковому тракті птиці від народження, особливо за технологій підлового утримання.
Declaratorias de veda en la subcuenca de Chapala: ¿medidas preventivas para la sobreexplotación de acuíferos subterráneos o incentivos para la industria?
Authors:   Universidad  de  Guadalajara, Rangel Muñoz José Luis , Sánchez Andrade Diana Elizabeth ,   Universidad  de  Guadalajara
Published: October 2022

La crisis de agua que presenta la subcuenca de Chapala desde mediados del siglo xx se puede explicar, en gran medida, a partir de la aplicación de una política hidráulica orientada por el gobierno federal sobre la cuenca del río Lerma para generar energía eléctrica y satisfacer las necesidades industriales de las ciudades de México y Guadalajara, además de una agricultura comercial impulsada sobre la parte media de esta área. Otra medida que explica esta crisis es la sobreexplotación, hasta ahora poco explorada, de acuíferos subterráneos. Es por ello que la presente comunicación tiene como objetivo central dar cuenta del sentido que tomaron las declaratorias de veda para la extracción de aguas del subsuelo en la subcuenca de Chapala, jurisdicción de los estados de Jalisco y Michoacán.
Cuando la multiplicidad se despliega en el tiempo: memorias indígenas en espacios desmarcados en la Comarca Andina del Paralelo 42°, Patagonia argentina
Authors:   Universidad Nacional de Río Negro, Alma Tozzini María
Published: October 2022

Construida la Comarca Andina del Paralelo 42°, Patagonia, Argentina, como una región sin origen indígena desde los discursos hegemónicos, el presente escrito persigue ahondar en un postulado metodológico que, para estos casos, propone abordar la historia indígena desde los bordes, esto es, desde historias, espacios, lugares y memorias a priori no marcados étnicamente. Para esto, me centraré en el análisis de dinámicas de memoria y de (re)territorialización operadas en espacios aparentemente desmarcados étnicamente, como son plantaciones abandonadas de pinos realizadas por consorcios madereros que operaron en la región entre la década de 1970 y 1990. Tras el intento de desalojo de una campesina en dicha región de las tierras que históricamente pertenecieron a su familia, y en las cuales se encuentran parcelas que habían pertenecido a estas forestaciones, di- chos espacios aparentemente neutrales fueron tomando nuevos sentidos históricos situados en el proceso de resistencia al desalojo. Aquellas fo restaciones se fueron convirtiendo en lugares de enunciación del despojo territorial de indígenas y campesinos pobres que los enhebraban a otros espacios a los que se les adjudicaban similares sentidos.
Fully Convolutional Architecture for Low-Dose CT Image Noise Reduction
Authors: Badretale Seyyedomid , Shaker F. , Babyn Paul , Alirezaie Javad
Published: October 2022

One of the critical topics in medical low-dose Computed Tomography (CT) imaging is how best to maintain image quality. As the quality of images decreases with lowering the Xray radiation dose, improving image quality is extremely important and challenging. We have proposed a novel approach to denoise low-dose CT images. Our algorithm learns directly from an end-to-end mapping from the low-dose Computed Tomography images for denoising the normal-dose CT images. Our method is based on a deep convolutional neural network with rectified linear units. By learning various low-level to high-level features from a low-dose image the proposed algorithm is capable of creating a high-quality denoised image. We demonstrate the superiority of our technique by comparing the results with two other state-ofthe-art methods in terms of the peak signal to noise ratio, root mean square error, and a structural similarity index. 
ANALISIS MODEL TARIKAN PERGERAKAN KENDARAAN MENUJU KAWASAN EKONOMI KHUSUS (KEK) WISATA TANJUNG GUNUNG KABUPATEN BANGKA
Authors: Gunawan Indra , Sandy Boy Dian Anugra
Published: October 2022

Di masa New Normal Pandemi Covid-19 kegiatan di sektor ekonomi, sosial, dan budaya mulai beraktifitas kembali. Begitu juga dengan kegiatan di sektor pariwisata yang mulai aktif kembali, didukung dengan Moda transportasi darat, laut, dan udara juga mulai giat kembali. Hal ini sesuai dengan keinginan Presiden untuk melakukan percepatan pemulihan ekonomi di masa pandemi Covid-19. Upaya ini juga merupakan salah satu komitmen Pemerintah Provinsi Kepulauan Bangka Belitung untuk fokus mengembangkan sektor pariwisata. Terdapat beberapa Kawasan Ekonomi Khusus Wisata di Provinsi Kepulauan Bangka Belitung, salah satunya ialah Wisata Tanjung Gunung. Tujuan dari penelitian ini adalah membuat suatu model yang digunakan untuk menghitung besar tarikan pergerakan kendaraan dan untuk mengidentifikasi dan menganalisis faktor-faktor yang mempengaruhi untuk mendapatkan model tarikan pergerakan kendaraan dan pengunjung di kawasan wisata Tanjung Gunung Kabupaten Bangka Tengah. Di area tersebut terdapat 3 detinasi wisata yang dapat dituju yakni Pantai Pan Semujur, Bukit Angsa Emas, dan Pantai Tapak Antu. Data yang diperoleh dengan melakukan uji korelasi dan kemudian dilakukan analisis regresi untuk mendapatkan model equations. Variabel bebas yang ditinjau antara lain: total luas Musholla (X1), total luas WC (X2), total luas Pondokan (X3), total luas Tempat Makan (X4), dan total luas Area Parkir (X5). Dari analisis regresi, ditemukan model yang baik untuk menarik gerakan adalah:  Y = -37,423 + 0,7203X4 dengan koefisien determinasi (R2) = 0,99, Model tersebut  menjelaskan bahwa variabel bebas yang mempengaruhi besar tarikan pergerakan kendaraan menuju kawasan wisata Tanjung Gunung adalah total luas tempat makan (X4).
ANALISIS KETERSEDIAAN AIR DAN KEANDALAN KULONG PL KECAMATAN PANGKALAN BARU MENGGUNAKAN MODEL SARIMA DAN SOR
Authors: Pririzki Sisillia Jesika , Adriyansyah Adriyansyah , Stevanus Hendy , Lusia Rohil Agatha
Published: October 2022

Desa Air Mesu dan Desa Jeruk merupakan dua desa yang terletak di Kecamatan Pangkalan Baru, Kabupaten Bangka Tengah, Provinsi Kepulauan Bangka Belitung. Jumlah penduduk di desa tersebut meningkat setiap tahunnya sehingga menimbulkan permasalahan yaitu bertambahnya kebutuhan air bersih di desa tersebut. Solusi dari permasalahan tersebut adalah memanfaatkan air Kulong PL sebagai sumber air baku untuk memenuhi kebutuhan air bersih di Desa Air Mesu dan Desa Jeruk. Untuk memastikan ketersediaan air Kulong PL mampu mencukupi kebutuhan air bersih di Desa Air Mesu dan Desa Jeruk maka akan dilakukan prediksi (forecasting) selama 10 tahun kedepan yaitu tahun 2021 sampai tahun 2030. Dari hasil analisis didapatkan model terbaik untuk memprediksi debit bangkitan yaitu SARIMA (0,0,0)(1,1,0)12 . Berdasarkan analisis SOR, pilihan terbaik dalam pemanfaatan Kulong PL difokuskan dalam satu desa saja. Jika penggunaan Kulong PL menginginkan keandalan 100%  maka penggunaan air yang diperbolehkan yaitu sebesar 3,06 l/det. Sedangkan untuk Desa Jeruk, Kulong PL mampu menyuplai 100% kebutuhan dengan tingkat keandalan 99%.
ANALISIS STABILITAS DINDING PENAHAN TANAH TERHADAP DRAWDOWN PADA LERENG SUNGAI AREA DAM BADENG KECAMATAN SONGGON, BANYUWANGI.
Authors: Nurshinta Holis , Putra Paksitya Purnama , Nurtjahjaningtyas Indra
Published: October 2022

Sungai Badeng yang berlokasi di Kecamatan Songgon Kabupaten Banyuwangi mempunyai debit yang sering meluap sehingga menyebabkan rusaknya dinding penahan tanah dan terkikisnya lereng tepi sungai area Dam Badeng.  Hal ini menjadi permasalahan bagi warga sekitar karena pemanfaatan air menjadi kurang maksimal dan dapat meningkatan resiko terjadinya banjir didaerah hilir sungai. Untuk mencegah agar tidak terjadi kelongsoran pada tepi sungai, maka dilakukan analisis stabilitas lereng dengan menggunakan dinding penahan tanah tipe gravitasi yang dapat menahan gaya guling, gaya geser, dan aman terhadap daya dukung serta memperhatikan drawdown. Analisis drawdown dimodelkan selama 20 jam pada kondisi awal muka air sungai surut menuju banjir lalu kembali pada kondisi semula. Pemodelan dilakukan dengan program bantu Geoslope studio.

Hasil analisis stabilitas gravity wall terhadap drawdown dinyatakan aman. Saat muka air sungai semakin tinggi, maka nilai safety factor lereng akan bertambah. Dan saat muka air sungai semakin turun, maka nilai safety factor lereng akan berkurang. Hal ini terjadi karena dipengaruhi oleh naik dan turunnya nilai tekanan pasif yang diberikan air terhadap lereng. Kondisi safety factor paling kritis terjadi saat kondisi surut karena masih adanya residu air sungai yang masuk kedalam pori-pori tanah. Analisis stabilitas terhadap  gaya guling, gaya geser, dan aman terhadap daya dukung juga dinyatakan aman.
Competence development as a tool to ensure social projects effective management
Authors: Rudych L. , Stetsenko V. , Shapovalov V.
Published: October 2022

Modern realities have many challenges for society and the economy, as the global economic crisis and Ukraine's internal economic and political problems are not conducive to development. Against the background of these challenges, the support of the whole population, the desire to improve the quality of life, in particular in socially vulnerable groups, is becoming important. Social projects in such conditions are designed to maintain social stability, improve the quality of life, and in turn require professional staff. The article examines the essence and features of social projects as a tool to improve the quality of life, ensuring the social effect of implementation, as well as the role of competence development in the context of ensuring effective management of social projects. The content of social project management in modern conditions as organization, planning, management, coordination of labor, financial and logistical resources during the project cycle, aimed at effectively achieving their goals and a certain social effect. Some principles of successful social projects are defined, which allows to increase the efficiency of their management. A certain algorithm of social project management has been formed, which includes: analysis of social sphere problems, determination of social sphere priorities, formation of social project management structure, development and implementation of social projects, achievement of results and social effect. The role of competencies, in particular managerial ones, in ensuring the effectiveness of social project management is determined. Based on the definition of the concept of «competence», the hierarchy of management staff competencies of the social project is revealed. The key competencies of the social projects management stafff, including leadership, discipline, forecasting social development, empathy, emotional intelligence, etc. are identified. Taking into account the specifics of managerial competencies, an algorithm for their development was formed to ensure the effectiveness of social project management in modern conditions, which involves certain stages from analysis of existing competencies of management staff to new competencies goals and objectives of the social project.
水质检测方法应用分析研究
Authors: 王 立航
Published: October 2022

随着人们对用水质量要求的提升，国家也越来越注重对水质的检测。水质检测是环境检测中最重要的部分，严重影响了我国绿色发展。调查表明我国水污染情况非常严重，因此加强水质的监测，并采用一定的措施减少水污染，是我们当下最重要的任务。本篇文章基于此，说明了水质检测的意义，简单介绍了检测的技术和方法，并分析了当下存在的问题，最后提出一些处理方法和相关注意事项。希望可以推动我国水资源的保护力度，改善我国水污染的现状。
探讨电力业扩报装流程的精细化管理
Authors: 王 举
Published: October 2022

近几年来，无论是生活用电还是工业用电，各行各业对于电力用量也在逐步增加。电力相对人们来说是极其重要的，如果没有了电，那么人们的生活将受到非常大的影响，因此电力不仅对于国家来说是一种很重要的能源，也关系到人们的日常生活，国家为了促进我国经济和社会的可持续性发展，鼓励大力开展可再生能源的发掘，电力能源正好符合这一要求。但是由于电力在人们生活和工作中广泛被应用，对于其服务质量和发展的要求也越来越高，于是，电力公司需要有一套完整的扩报装流程，而且还要对该扩报装地进行精细化管理的研究。针对电力业扩报装流程的精细化管理进行相关问题的分析和探讨，希望对电力企业的扩报装流程具有一定的指导性。
探讨输变电工程建设项目施工质量管理
Authors: 毕 清文
Published: October 2022

随着社会的不断发展，让人们对电能的需求也在增加，逐渐成为日常生活必不可少的重要能源，为了保证生产设备的正常运行和满足人们的基本需求，所以要加大输变电工程输电线路的建设规模，这样才能将电力能源进行合理的调配，以满足城市用电的需求，还可以提升传输质量。要重视输电线路的施工技术，不仅可以保证其安全性和有效性，而且还能为社会发展提供技术保障工作。
浅谈水质检测对人类生活的重要性
Authors: 崔 彩霞
Published: October 2022

最近这几年来，我们国家在经济领域当中做出了很多改革和创新，社会的整体实力越来越强，人们的生活水平相对于过去有了很大的提高，当前的水质检测工作受到越来越多人的关注和重视，饮用水水质的优劣其实和人们的日常生活有着非常紧密的联系，根据目前的实际调查看出，我们国家在这方面水质检测当中还有一些问题和需要改善的地方，针对这种情况我们必须要充分的意识到水质检测对于人类生活的重要意义，只有这样才能够更好的做出改善和调整，保证水体的质量。
低压管道输水灌溉在农田建设中的应用
Authors: 黄 赛雄 , 潘 国坠
Published: October 2022

低压管道输水灌溉是一种新型农业节水技术，也是一种管道供水的工程形式，在农田灌溉中能够提高灌溉的效果，而不是明渠配水系统，在与水源相同条件下，低压管道输水灌溉具有明显优势，能够起到高效节水的目的，这种高效的节水，既能有效满足作物生长的基本要求，又能增加产量和收入。
新时期农田水利建设的发展困境与对策
Authors: 张 丹
Published: October 2022

随着我国经济继续增长，为了加快农业建设，国家增加了农田水利建设，从而为农业生产提供了保障。农田水利是农业发展和建设的一个非常重要的组成部分。必须通过建设农田水利系统提高农业生产水平。但是，我们现在正处于一个新的阶段。在建设新农村的背景下，我国农田水利建设遇到了严重阻碍我国农田水利建设发展的问题。因此，在新时代背景下，分析我国农田水利建设目前面临的困难尤为重要。在此基础上，着重分析新时期我国农田水利建设发展面临的困难，提出相应对策。
浅析水利大坝工程防渗面板的施工技术
Authors: 买买提 米克仁沙 •
Published: October 2022

随着我国科技经济的快速发展，水利大坝工程领域的技术也同样发展迅速。我国的国土广袤，河流众多，这众多的河流流域情况各异十分复杂，这就需要河流开发建设多种多样的水利大坝工程。防渗面板施工内容是该工程施工中非常重要的环节，若该环节质量把控不到位，容易降低工程整体建设效果。文章对防渗面板施工技术流程进行探讨，加大质量管理控制，旨在提高水利大坝工程防渗能力进行分析。
提高小型水库运行管理模式初探
Authors: 李 晓杰
Published: October 2022

水库是用来储存水、输送水以及拦截和调节水流的建筑设施。这些技术广泛用于防洪、灌溉和水力发电等领域，为人民的生产生活带来了巨大的便利和经济利益。水库的储水能力很强，使人们能够在干旱时临时供水和灌溉农田。此外，水库可以截留水流，有效减缓水的传播，避免洪水泛滥。有效管理直接关系到水库的作用及其使用寿命。分析了水库运行管理的现状和问题，并提出了提高管理水平的技术措施。
水利工程建设管理中存在的问题与对策探究
Authors: 李 晓杰
Published: October 2022

在人们的日常生活以及具体的工作当中，对于水资源的应用都是非常频繁的，可以说水就是人们生命的支柱，如果离开了水，那么人们的生存也会成为一个难题。对于人们来说水的安全性对于人们的身体健康所产生的影响是非常严重的，人们的身体健康也会受到水资源的成分影响，针对水的质量属性可以通过水质监测这项工作，来对此进行有效的监督和严格的管理。确保经过了一定处理后，水质可以直接达到一定的标准和要求，可以尽量的减少对于人体的伤害，保证人们的生存。在进行检测工作的时候，需要对水的属性和指标进行更加全面的分析，确保水的属性质量，因此在当下进行水质检测工作的有效加强也非常的重要。
加强小型水利工程管理及节水灌溉技术研究
Authors: 依米提 阿同古力 •
Published: October 2022

水利工程是我国工程的重要组成部分，对提高农业效益、增加农民收入具有重要意义，因此，在建设小型水电站时，要注意加强项目管理，通过不断创新和应用节水灌溉技术，促进农业灌溉水平的有效提高，更好地促进农业经济发展，充分发挥水资源管理项目的作用，在此基础上，文章重点对当前小型水利工程项目管理和节水灌溉技术的应用进行了分析和探讨。
农田水利工程高效节水灌溉分析
Authors: 苏力坦 阿曼古丽 •
Published: October 2022

在国家政策和科技的支持下，农田灌溉正在蓬勃发展，但与实际需求相差甚远。特别是在水资源严重短缺的情况下，节能理念仍然是人们关注的焦点。必须采取具体的科学措施，在改善农业节水的项目中实施水保护。中国目前面临着日益严重的水资源短缺问题。因此，使用有效的灌溉方法对农业灌溉项目的有效实施非常重要。节水灌溉系统不仅是中国农业发展的标志，也是提高农业发展速度的一种手段。加强农业水文、高效灌溉和节水对促进农村经济发展和增加人民收入发挥了重要作用。因此，文章通过分析这些问题，提出了提高农村经济和农业供水水平的有效对策。本研究探讨了农业水文学中高效经济的灌溉方法，并介绍了改进灌溉技术和有效提高农业灌溉效率的措施。
试论电力新能源的开发利用及节能措施
Authors: 王 鹏举
Published: October 2022

电力新能源的开发利用是我国社会主义经济发展的必要工作，随着人民生活水平的不断提高，人民对电力的需求不断提高，但由于我国主要以火力发电方式，不仅能源的消耗，也会对环境造成破坏，所以需要减少电力的浪费。电力节能技术在电力技术中可以减少用电量，本文将主要研究电力新能源的开发利用及节能措施。
浅谈水利工程设计阶段的造价控制与管理
Authors: 邹 雷
Published: October 2022

伴随社会的不断进步和发展，各地水利工程建设速度越来越快。相关部门在开展水利工程建设工作时，必须切实掌握工程设计阶段的造价控制与管理工作。准确把握工程设计阶段的重点，降低施工建设的成本支出，全面提高水利工程建设的质量和效果。本篇文章将针对水利工程设计阶段的造价控制与管理的相关内容进行简单分析。
我国水资源管理及相关技术问题探讨
Authors: 张 丽娅
Published: October 2022

伴随着社会经济的发展与进步，水资源管理工作的价值与作用也愈加凸显。近年来，我国水资源匮乏问题成为社会各界高度关注的话题，同时加强节水工作的呼声也越来越高。水对于人类而言具有重大意义，既是生活的必需品，也在经济发展过程中具有关键作用。目前，我国面临着非常严重的水资源短缺问题，水污染情况十分严重。要想解决这一问题，提升水资源的利用率，就要针对水资源做好保护措施。随着人类数量的持续增多，对水资源需求的不断增大，传统的水资源管理模式已经不符合当今时代的发展，需要建立一套与时俱进的管理模式，从而实现水资源的可持续利用。文中分析现代水资源管理主要存在的问题，并对现代水资源管理中进行深入分析，从而提高现代水资源利用率，实现人类社会的可持续发展。
Upaya Preventif Penanggulangan Penyebaran Virus Covid-19 di Kelurahan Beringin Raya
Authors: Izharudin  , Antoni Sitorus  , Romi Gunawan
Published: October 2022

Beringin Raya has a vulnerability to the spread of the covid-19. This is because Beringin Raya come from various regions, especially boarding house residents, this area is the entrance to Bengkulu City which is directly adjacent to Mukomuko to West Sumatra Province. The purpose of this activity is as an effort to prevent the spread of the Covid-19 in the Beringin Raya Village and to support government programs in overcoming the Covid-19. The activity is in the form of socialization about California papaya cultivation which has benefits for the health (nutrition) of the residents of the Beringin Raya Village. The results that the community in Beringin Raya understands and uses the California Papaya as a medicinal plant in preventing the spread of the covid-19.
Error Elimination From Bloom Filters in Computer Networks Represented by Graphs
Authors: CAYLAK KAYATURAN Gokce
Published: October 2022

An undirected mathematical graph, $G = (V, E)$ where $V$ is a set of vertices and $E = V \times V$ is the set of edges, can model a computer network. By this consideration we search for solutions to real computer network problems with a theoretical approach. This approach is based on labelling each edge by a subset of a universal set, and then encoding a path as the union of the labels of its edges. We label each vertex $v \in V$ by using a subset of universal set $U$, then we present a way to encode shortest paths in the graph $G$ by using a way optimizing the data. By mathematical approach, it is provable that the labelling method we introduced eliminates the errors from the shortest paths in the graph. We aim to obtain the results in a more efficient use of network resources and to reduce network traffic. This shows how our theoretical approach works in real world network systems.
The Refractive Outcomes of Sutured and Sutureless Scleral Fixation (the Yamane Technique)
Authors: Lee Jae Hun , An Seoung Hyun
Published: October 2022

Purpose: To evaluate the pre- and post-operative refractive powers of patients undergoing sutured and sutureless scleral fixation (the latter: the Yamane technique).Methods: Patients who had undergone sutured or sutureless scleral fixation to treat intraocular lens (IOL) dislocation or phacodonesis at Dong-A University Hospital from January 2017 to December 2021 were retrospectively investigated. The preoperatively predicted spherical equivalents (derived using the radii of corneal curvature) were measured via optical coherence topography and the axial lengths were determined using an IOL master ® (Zeiss, Carl Zeiss Meditec, Jena, Germany) device and A-scan biometry (AL-100; Tomey, Nagoya, Japan) ultrasound. The spherical equivalent was measured 1 month after surgery employing an automatic refractive keratometer. The extent of agreement between the predicted and actual spherical equivalents were compared between the sutured and sutureless scleral fixation groups.Results: The sutured scleral fixation group included 20 eyes and the sutureless group 12 eyes. The preoperatively predicted spherical equivalent of the sutured group was -0.158 ± 0.577 diopters (D) on A-scan (Tomey) ultrasound and -0.143 ± 0.617 D employing the IOL master ® (Carl Zeiss Meditec); both correlated poorly with the postoperatively measured spherical equivalent of -0.400 ± 0.923 D (p = 0.903, 0.563). However, the predicted spherical equivalent of the group undergoing sutureless fixation was -0.340 ± 0.368 D on A-scan ultrasound and -0.183 ± 0.251 D using the IOL master ® (Carl Zeiss Meditec); both correlated significantly with the postoperatively measured spherical equivalent of -0.313 ± 1.129 D (p = 0.038, 0.005).Conclusions: The preoperatively predicted refractive power correlated significantly with the postoperative refractive power after sutureless but not sutured scleral fixation. Sutureless fixation was safe and the postoperative refractive power was comparable to that of sutured fixation.
Long-term Outcomes of Vitrectomy with Internal Limiting Membrane Removal to Treat Macular Hole Retinal Detachment
Authors: Jeon Young Joon , Kim Jong Woo , Kim Chul Gu , Yoo Su Jin , Kim Hyeong Seok , Kim Joo Yeon , Kim Jae Hui
Published: October 2022

Purpose: To evaluate the long-term clinical outcomes of vitrectomy with internal limiting membrane (ILM) removal for patients with macular hole retinal detachment (MHRD).Methods: We retrospectively reviewed the medical records of patients with MHRD who underwent vitrectomy with ILM removal. The incidence of retinal re-attachment and MH closure at 1 month were calculated. Factors associated with RD recurrence were investigated. Visual acuity before surgery was compared to that at the final visit.Results: Forty-two eyes were included; the mean follow-up period was 38.5 ± 19.1 months. Twenty-three eyes received gas injections and 19 silicone oil injections. Retinal re-attachment occurred in 41 (97.6%). Type 1 closure was noted in 21 eyes (51.2%) and type 2 in 20 (48.8%). Recurrent RD was noted in five eyes (14.6%) within 3 months of initial surgery. Type 2 closure was a risk factor for recurrence (p = 0.021). The logarithm of the minimum angle of resolution best-corrected visual acuity improved significantly from 1.79 ± 0.79 before surgery to 1.30 ± 0.75 after surgery (p < 0.001).Conclusions: Retinal re-attachment was noted in most patients and the MH closed in approximately half of all patients after vitrectomy with ILM removal to treat MHRD. RD did not recur later than 3 months after initial surgery. Further efforts to increase the rate of type 1 closure are required.
A Case of Nonarteritic Anterior Ischemic Optic Neuropathy after Intravitreal Aflibercept Injection
Authors: Joo Sungjun , Lee Joo Yeon , Baek Sung Uk
Published: October 2022

Purpose: To report a case of nonarteritic anterior ischemic optic neuropathy (NAION) development after intravitreal injection of aflibercept.Case summary: A 71-year-old female presented with decreased visual acuity and was diagnosed with wet macular degeneration in the right eye. She received two intravitreal aflibercept injections. After 1 month, the best-corrected visual acuity (BCVA) had improved. However, the inferior rim of the optic disc was blurred and an inferior retinal nerve fiber layer (RNFL) swelling was observed. The patient received one more intravitreal aflibercept injection (a loading dose). After 2 weeks, the patient presented with sudden vision loss and the BCVA was finger-counting at 50 cm. Fundus examination revealed that the total optic disc rim was blurred and optical coherence tomography demonstrated diffuse RNFL swelling. The patient was diagnosed with NAION. After 2 months, the optic disc appeared pale but without blurring of the rim, and diffuse thinning of the RNFL was observed. Her BCVA had not improved up to 6 months of follow-up.Conclusions: Although NAION after intravitreal injection is uncommon, physicians should not only examine the macula but also comprehensively assess the intraocular pressure, the RNFL profile, and the optic disc head, especially in patients with NAION risk factors.
Treatment Options in Eosinophilic Oesophagitis
Authors: Lipowska Anna M. , Kavitt Robert T. , Vaezi Michael F.
Published: October 2022

Eosinophilic oesophagitis (EoE) is an increasingly prevalent chronic inflammatory disorder diagnosed by the presence of oesophageal symptoms and eosinophilic inflammation on endoscopic histology. Treatment of EoE centres around the ‘3 D’s’: drugs, diet, and dilation, which aim to both improve symptoms and prevent potential complications. Potential pharmacologic therapies include acid suppressing agents and corticosteroids, among others. Dietary strategies comprise the elemental diet, the empiric elimination diet, and the allergy testing-directed elimination diet. The therapeutic landscape of EoE is rapidly changing as our understanding of the disease evolves. This review aims to provide a comprehensive discussion of existing EoE therapies and to outline an approach to EoE management.