bluuebunny/crossref_metadata_2025 huggingface dataset:
Thực trạng tuân thủ quy trình chăm sóc thiết yếu cho bà mẹ và trẻ sơ sinh trong và sau mổ lấy thai tại Khoa Phụ sản, Bệnh viện Trung ương Quân đội 108 năm 2021
Authors: Thanh Thuiy Nguyen , Quoc Kham Tran
Published: January 2022

Mục tiêu: Mô tả việc tuân thủ quy trình chăm sóc thiết yếu (CSTY) cho bà mẹ và trẻ sơ sinh trong và sau mổ lấy thai. Đối tượng và phương pháp: Các ca mổ đẻ và lãnh đạo các khoa phòng. Phương pháp nghiên cứu: Phương pháp dịch tễ học mô tả qua cuộc điều tra cắt ngang. Kết quả: Có 61,6% thực hiện tốt các bước chuẩn bị trước trước mổ, 94,4% thực hiện tốt việc tiến hành chăm sóc thiết yếu và theo dõi biến chứng đạt 100%. Tỷ lệ thực hiện tốt quy trình chăm sóc thiết yếu trong và ngay sau mổ lấy thai tại tất cả các bước chiếm 61,6%. Thuận lợi trong việc thực hiện quy trình CSTY: 7/7 ý kiến phỏng vấn sâu đều cho rằng: Cơ sở vật chất trang thiết bị đầy đủ, nhân viên y tế được đào tạo bài bản. Khó khăn trong việc thực hiện quy trình CSTY: Thiếu nhân lực CSTY khi mổ cấp cứu, hạn chế về chăm sóc chuyên khoa. Kết luận: Việc tăng cường giám sát chặt chẽ trong các ca mổ đẻ và cử nhân viên y tế tham dự các khóa học tập nâng cao năng lực là rất cần thiết.
Kết quả nghiên cứu ứng dụng và phát triển kỹ thuật ghép mô, bộ phận cơ thể người tại Bệnh viện Trung ương Quân đội 108 giai đoạn 2016 - 2021
Authors: Bàng Mai Hồng , Sơn Phạm Nguyên , Hoàng Nguyễn Thế , Khánh Lâm , Song Lê Hữu , Ngọc Nguyễn Hoàng , Lý Nguyễn Minh , Phương Lê Lan , Hải Ngô Vi , Thành Lê Văn , Viện Mai Văn , Đức Trần , Khoa Bùi Tuấn , Dũng Nguyễn Mạnh
Published: January 2022

Năm 2020 là một năm đầy khó khăn, thách thức đối với ngành Y tế Việt Nam và thế giới khi phải chiến đấu với đại dịch COVID-19. Trong tình hình đó, các nhà khoa học Việt Nam vẫn nỗ lực không ngừng nghỉ, lần lượt chinh phục những đỉnh cao của y học, được giới chuyên môn trong nước và cộng đồng quốc tế đánh giá cao. Tiêu biểu trong những thành tích đó là hai ca ghép chi thể được thực hiện tại Bệnh viện Trung ương Quân đội 108 (BV TWQĐ 108): Một ca ghép được thực hiện bằng cách sử dụng chi thể lấy từ người cho sống đầu tiên trên thế giới và một ca ghép hai cẳng bàn tay lấy từ người cho chết não lần đầu được thực hiện ở khu vực Đông Nam Á. Thông tấn xã Việt Nam đã bình chọn đây là một trong 10 sự kiện nổi bật của Việt Nam năm 2020.

Thực hiện các nội dung của Đề án khoa học công nghệ “Tăng cường năng lực nghiên cứu để phát triển kỹ thuật ghép mô, bộ phận cơ thể người tại BV TWQĐ 108”, trong giai đoạn 2016 - 2021, Bệnh viện đã triển khai nhiều đề tài nghiên cứu ứng dụng, tập trung đào tạo đội ngũ nhân lực chất lượng cao, bổ sung nhiều trang thiết bị hiện đại, đồng bộ đảm bảo thực hiện thành công các kỹ thuật ghép mô, tạng. Tính đến tháng 3/2021, Bệnh viện TWQĐ 108 đã thực hiện thành công kỹ thuật ghép 7 loại mô, tạng khác nhau trên 316 bệnh nhân, bao gồm: Ghép tế bào gốc 130 ca, ghép tủy 16 ca, ghép giác mạc 18 ca, ghép phổi 03 ca, ghép thận 78 ca, ghép gan 70 ca, ghép chi thể 02 ca, lấy - ghép đa tạng từ người cho chết não 05 ca; chức năng các tạng sau ghép tốt, kéo dài thời gian và chất lượng sống cho bệnh nhân, mang lại nhiều giá trị khoa học và giá trị nhân văn sâu sắc.

Hướng đi trọng tâm của Bệnh viện trong thời gian tới đó là tiếp tục phát triển các kỹ thuật ghép, triển khai thêm nhiều kỹ thuật khó như ghép mặt, ghép tụy, ghép ruột… nghiên cứu tạo nguồn mô tạng sinh học và vật liệu thay thế (công nghệ sao chép cơ quan 3D), tạng nhân tạo; kiểm soát vấn đề thải ghép; ứng dụng công nghệ thông tin, trí tuệ nhân tạo trong ghép tạng; tăng cường công tác tổ chức- điều phối ghép tạng, xây dựng nhiều chương trình vận động và vinh danh người hiến tạng.

Bài báo này tổng kết đánh giá các kết quả chính của quá trình triển khai nghiên cứu, ứng dụng kỹ thuật ghép mô, bộ phận cơ thể người của Bệnh viện TWQĐ 108 trong giai đoạn (2016-2021) - giai đoạn 1 của Đề án khoa học công nghệ “Tăng cường năng lực nghiên cứu để phát triển kỹ thuật ghép mô, bộ phận cơ thể người tại BV TWQĐ 108” và phương hướng phát triển kỹ thuật ghép tạng trong tương lai.
Xác định nồng độ kẽm, đồng, canxi trong huyết thanh và mối liên quan với lâm sàng ở bệnh nhân vảy nến mụn mủ toàn thân
Authors: Trang Nguyễn Thị Quỳnh , Em Đặng Văn , My Lê Huyền
Published: January 2022

Mục tiêu: Đánh giá nồng độ kẽm, đồng, canxi huyết thanh ở bệnh nhân vảy nến mụn mủ toàn thân. Xác định mối liên quan giữa nồng độ kẽm, đồng, canxi huyết thanh với lâm sàng ở bệnh nhân vảy nến mụn mủ toàn thân. Đối tượng và phương pháp: 49 bệnh nhân vảy nến mụn mủ toàn thân khám tại Bệnh viện Da liễu Trung ương thời gian từ tháng 07/2019 đến tháng 04/2020, 49 người khỏe mạnh nhóm chứng với tỉ lệ 1:1 về tuổi, giới. Nghiên cứu mô tả, cắt ngang, có nhóm đối chứng. Kết quả: Nồng độ kẽm huyết thanh: 0,85 ± 0,27mg/l thấp hơn có ý nghĩa so với nhóm chứng (p<0,001). Nồng độ đồng huyết thanh: 1,32 ± 0,26mg/l, tăng có ý nghĩa (p<0,001) so với nhóm chứng. Nồng độ canxi huyết thanh: 109,49 ± 11,15mg/l không khác biệt so với nhóm chứng (p>0,05). Không có mối liên quan giữa nồng độ kẽm, đồng, canxi với tuổi, giới, thời gian mắc bệnh, mức độ bệnh ở bệnh nhân vảy nến mụn mủ toàn thân. Kết luận: Ở bệnh nhân vảy nến mụn mủ toàn thân, nồng độ kẽm huyết thanh giảm, nồng độ đồng tăng, trong khi nồng độ canxi giảm không có ý nghĩa và không thấy mối liên quan giữa nồng độ các chất này với các yếu tố lâm sàng: Tuổi, giới, thời gian mắc bệnh và mức độ bệnh.
Nghiên cứu giá trị tiên lượng tử vong của troponin T độ nhạy cao ở bệnh nhân nhiễm khuẩn huyết
Authors: Hải Phạm Đăng
Published: January 2022

Mục tiêu: Xác định giá trị tiên lượng tử vong của troponin T độ nhạy cao (hs-cTn T) huyết tương ở bệnh nhân nhiễm khuẩn huyết. Đối tượng và phương pháp: 109 bệnh nhân nhiễm khuẩn huyết theo tiêu chuẩn của Hội Hồi sức châu Âu (SCCM/ESICM) năm 2016, điều trị tại Khoa Hồi sức tích cực - Bệnh viện Trung ương Quân đội 108 từ tháng 6/2017 đến tháng 12/2018. Nồng độ hs-troponin T huyết tương được định lượng bằng phương pháp miễn dịch điện hóa phát quang vào thời điểm 24 giờ đầu chẩn đoán nhiễm khuẩn huyết. Nghiên cứu tiến cứu, mô tả cắt ngang. Kết quả: Nồng độ hs-cTn T huyết tương có giá trị tiên lượng tử vong, với diện tích dưới đường cong ROC 0,65 (p<0,01), điểm cắt 35,5ng/L có độ nhạy là 84,6% và độ đặc hiệu 42%. Kết luận: Nồng độ hs-cTn T huyết tương có giá trị trong tiên lượng tử vong ở bệnh nhân nhiễm khuẩn huyết.
Đặc điểm tổn thương võng mạc mắt đái tháo đường ở bệnh nhân đái tháo đường tuýp 2 tại Bệnh viện Đại học Y Thái Bình
Authors: Bình Vũ Thanh , Quang Phan Ngọc , Tuân Lê Đình , Sơn Nguyễn Tiến
Published: January 2022

Mục tiêu: Tìm hiểu đặc điểm tổn thương võng mạc mắt và một số yếu tố liên quan ở bệnh nhân đái tháo đường týp 2. Đối tượng và phương pháp: Nghiên cứu mô tả cắt ngang trên 80 bệnh nhân đái tháo đường týp 2 đến khám và điều trị tại Khoa Nội, Bệnh viện Đại học Y Thái Bình từ tháng 1/2019 đến tháng 12/2019. Kết quả: Tỷ lệ bệnh nhân tổn thương võng mạc chiếm 42,5%; bệnh lý võng mạc không tăng sinh chiếm 38,8%, bệnh lý hoàng điểm chiếm 17,5%, bệnh lý võng mạc tiền tăng sinh 2,5% và bệnh lý võng mạc tăng sinh 1,2%. Nguy cơ tổn thương võng mạc mắt tăng cao hơn ở nữ so với nam; tuổi ≥ 70 năm; thời gian phát hiện đái tháo đường ≥ 10 năm; BMI ≥ 23 (kg/m2), nhóm tăng huyết áp với hệ số OR lần lượt là: 1,4, 2,5, 4,0, 4,5, 2,5. Bệnh nhân có nồng độ glucose máu ≥ 7mmol/L, nồng độ HbA1c ≥ 7%; nồng độ cholesterol > 5,2mmol/L, nồng độ triglycerid  > 1,88mmol/L có nguy cơ tổn thương võng mạc mắt cao hơn với hệ số OR lần lượt là: 2,3, 2,5, 3,2, 2,0. BN không tuân thủ điều trị có nguy cơ tổn thương võng mạc mắt lớn gấp 3,8 lần BN tuân thủ điều trị. Kết luận: Tỷ lệ bệnh nhân có tổn thương võng mạc mắt là 42,5%, nguy cơ tăng cao ở nhóm bệnh nhân nữ; tuổi ≥ 70 năm; thời gian phát hiện đái tháo đường ≥ 10 năm; BMI ≥ 23 (kg/m2), tăng huyết áp; nồng độ glucose máu ≥ 7 mmol/L, HbA1c ≥ 7%; cholesterol > 5,2mmol/L, triglycerid  > 1,88mmol/L.
Một số kết quả nghiên cứu ghép tạng thực nghiệm tại Học viện Quân y
Authors: Hai Đỗ Xuân , Đức Ngô Minh , Viện Mai Văn
Published: January 2022

Mục tiêu: Tổng hợp một số kết quả ghép tạng thực nghiệm tại Học viện Quân y. Đối tượng và phương pháp: Các nghiên cứu ghép tạng thực nghiệm: Ghép tim, ghép tụy - thận, ghép phổi, thực hiện trong giai đoạn 2010 - 2020. Phương pháp hồi cứu, tổng hợp một số kết quả theo tiêu chí đánh giá đề tài đã được thông qua. Kết quả: Tỷ lệ sống sau ghép cao (≥ 75%), nguyên nhân thất bại chủ yếu do tắc mạch ghép và hẹp miệng nối. Các công bố Quốc tế: Ghép tim: Truyền rửa qua tĩnh mạch chủ hiệu quả hơn qua động mạch chủ. Ghép tụy - thận: Xây dựng nhiều mô hình ghép tụy và ghép tụy với mạch máu đảo chiều. Ghép phổi: Xây dựng nhiều mô hình ghép, trong đó có tái tạo khí quản từ vạt da và sụn sườn tự thân. Truyền rửa lấy đa tạng theo phương pháp hòa loãng máu: Là mô hình mới, bước đầu có kết quả tạng tốt trên đại thể và vi thể. Kết luận: Ghép tạng thực nghiệm có vai trò quan trọng góp phần vào thành công cho ghép tạng trên người
Thủng chỗ nối xích ma trực tràng do xương vịt gây viêm phúc mạc: Thông báo 1 trường hợp
Authors: Tâm Nguyễn Thanh
Published: January 2022

Nuốt phải dị vật là một tình huống không hiếm gặp trong cuộc sống đặc biệt là ở trẻ em, người nghiện rượu, người thiểu năng trí tuệ, người móm răng hoặc mang răng giả... Trong phần lớn các trường hợp dị vật sẽ bị thải ra ngoài theo đường tiêu hóa trong khoảng 1 tuần mà không gây ra bất kỳ biến chứng nào. Chỉ một số ít trường hợp (dưới 1%) gây biến chứng thủng ruột. Các dị vật có thể gây thủng ở mọi vị trí của đường tiêu hóa như thực quản, tá tràng, ruột non, đại tràng… Tuy nhiên, thủng đại tràng do dị vật là rất hiếm gặp và ít được thông báo. Trong bài báo này chúng tôi thông báo một bệnh nhân nam 84 tuổi, móm răng, nghiện rượu bị thủng ở chỗ nối xích ma trực tràng do vô tình nuốt phải xương vịt, gây viêm phúc mạc. Bệnh nhân được mổ nội soi cấp cứu lấy dị vật, khâu kín lỗ thủng, lau rửa dẫn lưu ổ bụng. Sau mổ bệnh nhân diễn biến tốt và ra viện an toàn sau 10 ngày nằm viện.
Thực trạng và hiệu quả điều trị sâu răng sớm ở trẻ 36 đến 71 tháng tại Thành phố Hà Nội
Authors: Hưng Hà Văn , Ngọc Võ Trương Như , Tới Chu Đình
Published: January 2022

Mục tiêu: Mô tả thực trạng sâu răng sớm và đánh giá hiệu quả điều trị sâu răng giai đoạn sớm bằng vecni fluor. Đối tượng và phương pháp: Nghiên cứu mô tả cắt ngang thực hiện trên 200 trẻ, tuổi từ 36 đến 71 tháng tại trường Mầm Non xã Châu Can, huyện Phú Xuyên, thành phố Hà Nội, phân loại sâu răng dựa theo tiêu chuẩn đánh giá và phát hiện sâu răng quốc tế ICDAS II. Nghiên cứu can thiệp không đối chứng trên 150 răng được chẩn đoán là sâu răng giai đoạn sớm từ nhóm nghiên cứu mô tả cắt ngang trên và được điều trị bằng MI vanish fluor với liệu trình điều trị một tuần một lần trong 4 tuần liên tục, đánh giá kết quả điều trị sau 6 tháng. Kết quả: Tỷ lệ sâu răng sớm là 82%, sâu răng nghiêm trọng (S-ECC) là 65,2%. Sau 6 tháng mức độ phục hồi hoàn toàn (D0) tổn thương là 120 (80%), D1 là 20 (13,33%) và D2 chỉ còn 10 (6,67%). Kết luận: Tỷ lệ trẻ mắc sâu răng sớm khá cao và mức độ sâu răng nghiêm trọng khá nặng nề, tuy nhiên với những trẻ được điều trị bằng MI vanish fluor với liệu trình mỗi tuần một lần trong 4 tuần liên tục thì tỷ lệ bệnh sâu răng giảm và giảm cả mức độ của bệnh.
Impact of Lockdown during COVID-19 pandemic on psychological wellbeing among healthy working adults
Authors: RAJU Janula , ASİRVATHAM Raju , MADANİ Amna Hussian
Published: January 2022

The aim of this study was to assess the impact of lockdown during COVID-19 pandemic on psychological wellbeing among healthy working adults. This qualitative, cross-sectional study was conducted in Kanyakumari District, Tamilnadu, and the southernmost state of India. A convenient sample of 610 healthy working adults was participated and completed a self-administered questionnaire. The data collection tool contains two sections including baseline information, assessment of psychological wellbeing. Chi-square χ² test was used to test the association between demographic variables and scores of psychological wellbeing. One way ANOVA test was used to compare the mean score between groups. Descriptive statistics were used to describe the frequencies of variables. A significant P value was set at 0.05 at 95% confidence interval. The majority of participants (31.8%) belonged to 41-50 years of age. More than half (56.9%) of participants were females. The study findings revealed that 16.4% were had poor psychological wellbeing, 53.8% were had an average level, 21.3% had a good level and 8.5% were had an excellent level of psychological wellbeing. Additionally, gender, age, monthly income, history of quarantine, tested positive for the Corona Virus had a strong association with Psychological wellbeing. The study results concluded that the lockdown during the COVID-19 pandemic had a strong association with the psychological wellbeing of working adults. It also suggested having highly prioritized actions for early recognition of psychological problems, expanding counseling activities by the health authorities to avoid negative outcomes due to the Covid-19 pandemic lockdown.
نسق السلطة عند العسكريين : دراسة تطبيقية على الجيش السوداني
Authors: نبيل محمد دقيل
Published: January 2022

نسق السلطة عند العسكريين : دراسة تطبيقية على الجيش السوداني

This study tries to shed some light on the theme: system of authority in the military.

Much discussion has taken place about the usefulness of the rigid and restricted way of power and authority in the Armed Forces.

Some writers were in favor (pro), while others were against the implementation of authority and power in the Military in such a rigid way.

Many writers pointed out a distinction between Military bureaucracy and the civilian counterpart.

It is clear that authority and power in the Army is legitimate and has its justification
Lingkungan Pendidikan Islam Dalam Perspektif Al Qur’an
Authors: Bt Abdul Rahman Waheeda
Published: January 2022

Human caliph, has a big and important responsibility in protecting and preserving everything on this earth. To be able to create humans as caliphs or leaders who are fathonah, mandate, siddiq for tabligh, of course it requires knowledge and education, especially those based on the Qur'an and Hadiths, it must be applied from an early age.Feathered birds gather together. Birds with the same feathers will gather together. Shows how the importance of the environment affects a human being. Nature versus nurture is a fun thing that is often done by psychologists, educationists, sociologists and anyone with knowledge related to humans. Will a human being know more about his seeds or heredity, namely nature, or care, from the environment, education, family upbringing and government? The two terms above indicate the role that the environment affects on an individual's personality, especially the educational environment.The Islamic education environment in the perspective of the Qur'an can be a solution to form perfect human resources, which are beneficial to Islam and the nation. Like the adage, "Baldatun toyyibatun wa robun ghofur" in a good country, Allah SWT. will give forgiveness. Human resources formed from a good environment and country will be the basis for forgiveness and compassion from Allah SWT.In order to understand more clearly about what and how the nature of the educational environment is extracted from the verses of the al-Qur'an, it is necessary to conduct an in-depth study of the educational environment according to the al-Qur'an.
Wawasan Al-Qur’an Tentang Respon Iblis Terhadap Perintah Sujud
Authors: Muhtolib Muhtolib , Fauzi Umar
Published: January 2022

Iblis is a creature of Allah SWT, who created from fire while Adam was created from the ground. His story is mentioned repeatedly in several surahs in the Qur’an. When Iblis was ordered by Allah SWT to prostrate to Adam, the Iblis was arrogant and considered himself better than Adam. So that Iblis becomes a group of infidels. This is expressed by Theological commentator based on QS. al-Baqarah [2]: 34. While according to Sufistic scholars, the Iblis is a creature of Allah SWT, who has ever had the most noble position and the highest monotheism towards Allah SWT. His reluctance to carry out Allah's command to prostrate to Adam is as proof that Iblis truly tawheed to Allah SWT and does not want to prostrate to other than Allah SWT.When rejecting the command to prostrate to Adam, Iblis considered the commandment of prostration as a form of test of monotheism. In the end, Allah SWT will forgive his sins and put them in heaven. The author tries to analyze these two problems by using the method of interpretation maudhu 'i, namely by collecting verses related to the story of Iblis in the Qur’an.
Peran Citra Destinasi Pada Hubungan E-Wom Dengan Minat Kunjungan Wisatawan Di Pantai Losari, Kota Makassar
Authors: Sarapang Vinny Corylitha , Surata I Ketut , Utama I Putu
Published: January 2022

This study sees and analyzes the direct effect of e-WOM on visit intention and destination image, the direct effect of destination image on visit intention, and the indirect effect of e-WOM on visit intention through destination image. The methods of this study used a quantitative approach. I collected data through online questionnaires with a total sample of 200 respondents. The sampling technique used is purposive accidental sampling. Data analysis used the SEM-PLS method. The results showed that e-WOM has no direct effect and an insignificant positive relationship on visit intention, e-WOM has a positive and significant direct effect on destination image, destination image has a positive and significant direct effect on visit intention, and e-WOM has a positive and significant indirect effect on visit intention through destination image or destination image became a mediator between e-WOM and visit intention.
Analisis Penerapan Cleanliness, Health, Safety and Environmental Sustainability di Kawasan Wisata Kuliner Pasar Lama Tangerang
Authors: Indra Febryola
Published: January 2022

Kebijakan Cleanliness, Health, Safety, dan Environmental Sustainability (CHSE) ini dibagi berdasarkan panduan umum dan khusus yang menjadi syarat pengaplikasian pada rumah makan yang kemudian dilanjutkan dengan uji verifikasi oleh Kementerian Pariwisata dan Ekonomi Kreatif dan Lembaga Sertifikasi dari Indonesia Sustainable Tourism Certification (ISTC) baik oleh Global Sustainable Tourism Council (GSTC) atau Komite Akreditasi Nasional (KAN) untuk memperoleh legalitas rumah makan dapat beroperasi selama kondisi pandemi dengan adanya bukti labelling/sertifikasi. Adapun tujuan dari penelitian ini adalah untuk menganalisis penerapan cleanliness, health, safety dan environmental sustainability di Kawasan Wisata Kuliner Pasar Lama Tangerang. Jenis penelitian yang tim peneliti gunakan dalam penelitian ini adalah penelitian deskriptif kualitatif. Berdasarkan hasil penelitian dan pembahasan pada bab sebelumnya dapat ditarik beberapa kesimpulan guna menjawab rumusan masalah. Beberapa kesimpulan tersebut terdiri dari :Sebagian besar pedagang yang berjualan di Wisata Kuliner Pasar Lama sudah memahami konsep dari penerapan CHSE yang dianjurkan pemerintah, para pedagang yang berjualan di Wisata Kuliner Pasar Lama dapat memahami, menyatakan pengetahuannya serta menjalankannya mengenai penerapan cleanliness atau kebersihan, para pedagang yang berjualan di Wisata Kuliner Pasar Lama dapat memahami, menyatakan pengetahuannya serta menjalankannya mengenai penerapan health atau Kesehatan, sebagian pedagang yang berjualan di Wisata Kuliner Pasar Lama dapat memahami, menyatakan pengetahuannya serta menjalankannya mengenai penerapan safety atau keselamatan.para pedagang yang berjualan di Wisata Kuliner Pasar Lama dapat memahami, menyatakan pengetahuannya serta menjalankannya mengenai penerapan Environmental sustainability atau kelestarian lingkunga, sosialisasi tentang CHSE belum dilakukan secara menyeluruh, berdasarkan hasil wawancara sebagian Narasumber belum mendapat sosialisasi mengenai penerapan CHSE.
Deriving topological relations from topologically augmented direction relation matrices
Authors: Dube Matthew P.
Published: January 2022

Topological relations and direction relations represent two pieces of the qualitative spatial reasoning triumvirate. Researchers have previously attempted to use the direction relation matrix to derive a topological relation, finding that no single direction relation matrix can isolate a particular topological relation. In this paper, the technique of topological augmentation is applied to the same problem, identifying a unique topological relation in 28.6% of all topologically augmented direction relation matrices, and furthermore achieving a reduction in a further 40.4% of topologically augmented direction relation matrices when compared to their vanilla direction relation matrix counterpart.
Små barns kulturskapande och kamratsocialisation
Authors: Michélsen Elin
Published: January 2022

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Metformin related adverse events: A prospective observational study in health care centers of western Odisha
Authors: Kar Sanjeeb Kumar , Khuntia Susovita , Nayak Shubhrata
Published: January 2022

Introduction: The most common adverse drug reactions were lactic acidosis followed by hypoglycemia, hypersensitivity reactions, nausea, decreased appetite, vomiting, weakness, and diarrhea.

Objectives: The study was done to explore the management of the patients having diabetes by primary care physicians, and the adverse reactions associated with the dose regimens. This study provided information regarding the adverse drug reactions that could be developed in any patient and increases the risk to the patient.

Methods: A qualitative In-Depth Interview study was conducted among the primary care physicians at ten primary health care centers at Sambalpur city of Odisha, India. The data were analyzed using content analysis. This was a prospective observational study (March 2019 - September 2019) among diabetes patients receiving metformin. Data were collected and analyzed to find out the demographic characteristics, causality, and severity of adverse events with metformin regimens.

Results: It was seen that 8 % of cases could be assessed as certain and 24 % could be assessed as probable. Most (60 %) cases were assessed as possible. Severity assessment of ADRs by modified Hart wig and Siegel's severity Scale (n=143) indicates 64% of the case were mild and 34% of cases are moderately severe.

Conclusions: Hence with an aim of patient safety quality of the drug formulations has to be improved that could ultimately improve drug safety.
Nevirapine induced Stevens Johnson syndrome
Authors: Prajapati Himani , Neetu Bala  , Kansal Dinesh
Published: January 2022

Introduction: Severe and life-threatening SJS is more common with nevirapine than with other NNRTIs

Case presentation: A 56-year-old male patient presented with a complaint of lesions all over the body with a burning sensation for 4 days. He was on an ART regimen, containing zidovudine, lamivudine, and efavirenz combination for 4 years. But patient accidentally started nevirapine and after 10 days he developed maculopapular lesions which were diagnosed as SJS syndrome. There was a history of rash with nevirapine when ART was started initially in 2012. This incident of an adverse event could be assigned a term "probable" according to the WHO-UMC scale for causality assessment as the re-challenge was found positive.

Conclusion: Physicians and patients must be aware of this adverse effect on early diagnosis and treatment.
Ecopharmacovigilance: Perspectives, concepts, applications, and relationships in modern context
Authors: Prachi Khamkar  , Debarshi Kar Mahapatra  , Atul Kadam
Published: January 2022

Introduction: Environmental scientists have made great strides to regulate pharmaceutical waste. However, the monitoring of emerging environmental problems induced by drugs should attract the further interest of pharmacy and pharmacovigilance scientists. Ecopharmacovigilance (EPV) as a kind of pharmacovigilance for the atmosphere is widely recognized as essential to minimize the environmental impact of pharmaceutical toxins.

Methods: In efforts to answer the environmental issues created by medications, the constructive involvement of the pharmaceutical sector is essential. On a prioritized basis, EPV can target individual pharmaceuticals. For EPV deployment targeting pharmaceutical contamination, certain advice and management practice solutions are recommended. On administration certain drugs are metabolized throughout the bloodstream, being inert or becoming converted to metabolites, whereas others are excreted in the urine or liver and excreted in the sewage. The substances that are released into drainage can be processed into a number of chemicals by a sewage treatment process.

Results: The involvement of different drugs and their components have been found in the marine world, with the aquatic environment being the most researched to date. Nanostructure materials have been around for a long time, and their interactions with biological processes have been discussed in various applications to enhance the understanding and importance of environmental and health effects.

Conclusions: In order to regulate pharmaceutical residues in effluents, Technologies for sewage water management should be applied.  In particular, the presence of pharmacy including pharmacovigilance professionals is also important for enhancing multidisciplinary collaboration.
A two-year retrospective observational study of adverse drug reactions related to intravenous drug formulations
Authors: Ramani Gade  , Neeraj Sadiq  , Shivaraj B Patil  , Venkata Rao Y  , Raghuveer B  , Yamini V  , Sindhu P
Published: January 2022

Introduction: Adverse drug reactions are the major obstacles to patient safety and drug therapy monitoring.

Objectives: The present article provides information on intravenous products induced adverse drug reactions collected by spontaneous reporting method through an established pharmacovigilance wing working under NCC-PVPI in an Adverse Drug reaction monitoring center-Nalgonda, Telangana.

Methods: A total number of 100 intravenous products induced ADRs were collected from different age groups by observational retrospective study for the year January 2018 to December 2019.

Results: The results showed that the most affected age group was 20-29 yrs (28 %). The major contribution of the gender that exposed to ADRs was female- 73 % Most intravenous product induced ADRs were reported from the Department of OBG (46 %). Drug: Ceftriaxone-induced ADRs were (38 %). The most frequently reported ADR was fever and chills (56 %). Out of 100 ADRs, one was certain, 90 were probable/likely, and the remaining 9 were possible as per the WHO-causality scale.

Conclusions: In the present work, most of the ADRs were because of intravenous antibiotics followed by anesthetic agents, antiepileptic drugs, ringer lactate, dextrose normal saline, and H2 blockers.
Geotecnologias como ferramenta a serviço do planejamento urbano: Uma análise para implantação de UBS em Boa Vista (Roraima) - 2019
Authors: Oliveira Nikson , Silva Adriano , Borges Elton
Published: January 2022

O presente estudo aborda a demanda pela implantação de Unidades Básicas de Saúde (UBS) localizadas sobre o perímetro urbano de Boa Vista, capital do estado de Roraima, em julho de 2019. Assim, buscou-se indicar, ao longo do tempo e do espaço, a evolução da implantação de novas UBS’s, e identificar por meio de um índice a demanda por setores censitários os territórios com maior demanda pela implantação de novas unidades básicas de saúde, a partir de um levantamento da distribuição das mencionadas unidades de atenção primária à saúde e de variáveis demográficas e infraestruturas urbanas, para que então, possa traçar proposituras para a implantação de novas UBS em áreas até então desassistidas. A metodologia aplicada foi da pesquisa geográfica, descritiva, analítica e propositiva, baseada em dados quantitativos. A análise dos resultados identificou em um universo de 389 setores censitários utilizando 6 variáveis e um perfil que possibilita a instalação de UBS’s com maior equidade para os habitantes do perímetro urbano da cidade de Boa Vista, capital do estado de Roraima, locus desta pesquisa. Ainda foram apresentadas proposições contra alguns dos principais entraves ao Planejamento Urbano da Assistência à Saúde neste que pode ser reconhecido como mais um esforço para a promoção de maior justiça socioespacial empreendido pela Geografia da Saúde para a melhoria da saúde coletiva em Boa Vista. Dessa forma espera-se que este estudo possa contribuir para reflexões e melhor planejamento da Saúde Coletiva no Brasil e em Roraima.
ARABIC-2 The Chapter of Fatiha; Its Names, Objectives, Virtues and Features: Analytical Study of the Relevant Hadith Literature
Authors: Majid Ghouri Dr Syed Abdul
Published: January 2022

The Chapter of Fatiha is conceived as one of the paramount chapters of the Holy Qur’an; rather, it is unprecedented one in the sense that not a similar chapter has been revealed in any of revealed Books including the Qur’an itself. Also, as many prophetic traditions have been narrated with regard to its virtues as not narrated concerning any other chapter; the objectives of this chapter have extensively been discussed more than other chapter; and this chapter is characterized by having many names more than all other chapters. Moreover, this chapter, despite of being conciseness, comprises of three types of Tawhid (Oneness of God); namely, Oneness in terms of Lordship, Oneness in terms of Divinity, and Oneness in terms of Names and Attributes. Similarly, this chapter is characterized with many other features: such as the role of this chapter in attracting benefits and removing harms, healing of deceased, (getting divine) guidance, and fulfilling necessities. In addition to this, the Qur’an begins with this chapter. It is stated that it is one of the basic elements of the prayer without which prayer does not stand valid. It, by all means, indicates to the sublime nature, great features and magnificent virtues that this chapter holds. This work analyses the prophetic traditions narrated concerning this chapter and focuses over its objectives, names, virtues and characteristics in the light of authentic prophetic traditions. Meanwhile, the researcher adopts hybrid methodology: namely inductive one and critical one. On the one hand, critical method is adopted for searching and gathering all relevant traditions that discuss in one way or another this chapter; and, on the other hand, inductive method is adopted for analyzing the relevant traditions and drawing significant conclusions therefrom. At the end, a conclusion is added that contains several important remarks which have been drawn while this study.
Editorial Foreword
Authors: Leon Crina
Published: January 2022

The second issue of volume 11 of The Romanian Journal for Baltic and Nordic Studies includes on the one hand topics of interest for scholars focusing on Medieval Studies, and on the other hand, further approaches aspects related to dissent and conformism, which were tackled during the tenth annual international conference on Nordic and Baltic studies in Romania. The conference entitled Dissent versus Conformism in the Nordic, Baltic and Black Sea Areas was held in Constanţa between June 6-8, 2019.
Finnish Literature Meets Romanian Literature in Hungarian. The case of the La Fontaine Literary Society
Authors: Varga Ildikó P.
Published: January 2022

In this study, I examine how Finnish literature meets Romanian literature in the activities of a literary society based in Hungary, the La Fontaine Society. Using André Lefevere’s concepts (literary system, rewriting, patronage, institutions, poetics, ideology, manipulation), I am looking for the answer to what motivated the selection of works for translation and publication.
My aim is to show and point out the factors that facilitate the meeting of two peripheral or small literatures, literary systems in a third language, which can also be considered peripheral and small – through translations.
Economic relations between Sweden and Romania during the Second World War
Authors: Dahlquist Andreea
Published: January 2022

The growth of Swedish-Romanian trade increased after Sweden opened its first diplomatic representation on Romanian soil in Galați (1851), Brăila (1852), Bucharest (1852), and Constanța (1880). In 1922, Sweden and Romania signed the first convention that regulated commerce. Later, in 1929, Romania took a loan of 30 million dollars from a Swedish concern in what proved to be a significant moment in the history of Swedish-Romanian economic relations.During the Second World War, both countries faced difficulties maintaining stable trade as a result of economic pressure from Germany and, eventually, the Soviet Union. Despite the challenges, Sweden succeeded in importing Romanian oil products, fodder, and grains – essential products for their economy – while Romania purchased Swedish agricultural machinery and other technologies.By the end of the war, several Swedish companies had established operations in Romania; among them, internationally recognized companies such as Swedish Matches, Kullager, Elektrolux, L.M. Ericsson, and Elektro-Invest.
Norwegian emigration and the emergence of modernity in Norway: America letters and the cases of Knut Hamsun and Sigbjørn Obstfelder
Authors: Mureșan Ioana-Andreea
Published: January 2022

Norway was going through important changes in the 19th century. It was a time of disruption, when the old rural society was transformed by the growing industrialisation, by the development of transportation and the expansion of free trade, when internal migration reached its peak as farmers struggled to survive using the old ways of living that had been passed on from generations and that no longer seemed to work in the modernized world. This paper argues that, although the need for change of the old habits was at the basis of the mass exodus to the New World, migration facilitated the emergence of modernity in Norway. America letters played an important role, as they both convinced the families and friends of the emigrants to embark for America, but they also helped increase the literacy rate in the homeland. Further on, the discussion will focus on the American experience of Knut Hamsun and Sigbjørn Obstfelder, which helped them gain recognition as forerunners of modernism in Norway
The sense of space and Arctic nature in Cora Sandel’s Kranes konditori: interiør med figurer (Krane’s Café: An Interior with Figures)
Authors: Răduț Raluca-Daniela
Published: January 2022

The paper combines the close reading technique of the novel Kranes konditori: Interiør med figurer (Krane’s Café: An Interior with Figures, 1946), written by the classic Norwegian writer Cora Sandel (1880-1974) with a spatial approach which aims to present the past and the present of the novel’s main character, Katinka Stordal. The action takes place in a small town situated in northern Norway, at Krane’s Café. It is worth noting how topography, the seasons of the year, the Arctic climate and nature are gradually reflected in the novel. On the one hand, the novel is placed at the crossroads of a spatial perspective and the literary criticism, which has in its centre Krane’s Café, the place where almost all the characters are brought together and which is the most suggestive and representative interior space of the novel. On the other hand, the subtitle An Interior with Figures strengthens the idea of a mixture of literary genres which includes elements from novel and drama. Moreover, it resembles the title of a work of art, for instance, a painting where all the characters are simply figures animated by the beauty of the Arctic scenery.
Combining soft power with the geopolitical approach – how difficult is for the EU to change its attitude?
Authors: Carp Radu
Published: January 2022

After gradually evolving from an economic project to a political one, European Union leaders declare nowadays that it is time to go forward and to build a geopolitical actor on the international stage. This paper does make an account on the current stage of relevant geopolitical actors and how they view EU. In order to address this issue, EU have to focus more on its soft power instruments, like multilateralism and the promotion of democracy, rule of law and human rights, and also climate change, apart from hard power instruments like trade, security and defense, cybersecurity and data privacy.
Paths to Learning Second Languages in Finland
Authors: Furu Adél
Published: January 2022

This article is concerned with comparative approaches to second language instruction and second language choices in Finland and describes the challenge of preserving Finland’s language and culture while facing the globalization process. The article discusses the success of Finnish second language learning and aims to investigate how Finnish and English as second languages are taught and learnt in Finland compared to other countries as well. The goal of this study is to discuss issues related to teacher training and its role in second- or even third language acquisition.
We articulate the following research questions: How does the English-language teaching line serve the international families? How does Finland develop successful teaching practices and what problems of implementation does it face? What are the challenges of teaching the pupils’ mother tongue and a second language (L2) (Finnish, Swedish, English, Russian etc.) at different levels of education? What are the differences between acquiring a Finnish or an international degree concerning adult education?
The methodology chosen for this article is a comparative study and it is used to showcase the differences between the Finnish and English second language instruction in Finland. In regard to the theoretical framework to second or foreign language acquisition, learning and teaching, I embrace linguistic, cognitive and sociocultural frameworks and approaches
Association of Serum Ferritin with Risk of Anemia in Non-Diabetic Adolescents with Family History of Type 2 Diabetes Mellitus
Authors: Mahmood Maira , Ashraf Huma , Qayyum Anoosh , Sijjeel Farwa , Ahmad Nizami Naim , Rashid Shazia
Published: January 2022

Background: Controversy occurs in the relationship between serum ferritin levels, insulin resistance and risk of developing anemia in adolescents with family history of diabetes.
Aims & Objectives: This study was designed to find out the association between serum ferritin levels with risk of developing anemia in non-diabetic adolescents with family history of type 2 diabetes mellitus (T2DM).
Materials & Methods: A descriptive cross-sectional was conducted in a local medical institute of Lahore. Study included 50 non-diabetic, non-obese male / female adolescent with family history of type 2 diabetes mellitus and 50 healthy male/female non-obese adolescents without family history of T2DM considered as controls. Level of serum ferritin and serum insulin was estimated by Enzyme Linked Immunosorbent Assay. Blood glucose was estimated by auto-analyzer. Insulin resistance was calculated by HOMA-IR index and beta cell function was assessed by HOMA- beta index.
Results: Levels of fasting blood sugar, insulin resistance were found to be increased with decreased level of serum ferritin and decrease beta cell function in both male as well as female cases as compared to controls. Negative correlation was found between serum ferritin and insulin resistance while a positive correlation was found between serum ferritin and beta cell function.
Conclusions: Low level of serum ferritin is associated with reduced beta cell function and increased insulin resistance. This may increase the risk of developing iron deficiency anemia that can affect both immune system as well as increase susceptibility to infections.
Booster Dose of COVID 19 and Ethical Issues
Authors: Shahid Adeela
Published: January 2022

COVID 19 is a recent and global pandemic. Preventive medicine is not very popular in Pakistan. With the limited resources, an average Pakistani would spend on a medical treatment rather than on a preventive drug. In Pakistan, booster shots are recently made available only to those who can pay for the cost of the vaccine. A Utilitarian approach has been adopted at various levels since the pandemic emerged by health care organizations and the government. The purpose was to maximize the benefits and minimize the risk of harm. It is the need of the hour to think about health equity and justice in a pluralistic way and refrain from initiating booster shots for elite of a resource-poor country. This pandemic will never end if a maximum number of people are not vaccinated in each country. This is only possible if there is an equitable distribution of vaccines.
SELECTION OF BEST CRYSTAL STRUCTURE FOR INITIATING DOCKING-BASED VIRTUAL SCREENING STUDIES OF CDK2 INHIBITORS: A CROSS-DOCKING AND DUD SET VALIDATION APPROACH
Authors: Joshi A. , Bhojwani H , Joshi U ,   Department of Pharmaceutical Chemistry, Prin. K. M. K-undnani College of Pharmacy, Cuffe Parade, Mumbai - 400 005, Maharashtra, India
Published: January 2022

A total of 95 crystal structures of CDK2 were selected after considering criteria such as resolution and absence of missing residues in the active site; and subjected to cross-docking. 14 out of 95 crystal structures exhibited docking accuracy for greater than 70% of ligands at RMSD cut off 2Å in the cross- docking studies. These 14 crystal structures were selected for the second part of the study, which included validation using DUD sets and enrichment calculations. 8 out of 14 crystal structures possessed the enrichment factor of >10 at 1% of the ranked database. ROC-AUC, AUAC, RIE, and BEDROC were calculated for these 8 crystal structures. 2WXV produced maximum BEDROC (0.768, at α=8) and RIE (11.22). 2WXV as a single initial crystal structure in the virtual screening protocol is likely to produce more accurate results than any other single crystal structure.
Improved Deep Hiding/Extraction Algorithm to Enhance the Payload Capacity and Security Level of Hidden Information
Authors: Ahmad Marwa , EL-Emam Nameer N. , AL-Azawi Ali F.
Published: January 2022

Steganography algorithms have become a significant technique for preventing illegal users from obtaining secret data. In this paper, a deep hiding/extraction algorithm has been improved (IDHEA) to hide a secret message in colour images. The proposed algorithm has been applied to enhance the payload capacity and reduce the time complexity. Modified LSB (MLSB) is based on disseminating secret data randomly on a cover-image and has been proposed to replace a number of bits per byte (Nbpb), up to 4 bits, to increase payload capacity and make it difficult to access the hiding data. The number of levels of the IDHEA algorithm has been specified randomly; each level uses a colour image, and from one level to the next, the image size is expanded, where this algorithm starts with a small size of a cover-image and increases the size of the image gradually or suddenly at the next level, according to an enlargement ratio. Lossless image compression based on the run-length encoding algorithm and Gzip has been applied to enable the size of the data that is hiding at the next level, and data encryption using the Advanced Encryption Standard algorithm (AES) has been introduced at each level to enhance the security level. Thus, the effectiveness of the proposed IDHEA algorithm has been measured at the last level, and the performance of the proposed hiding algorithm has been checked by many statistical and visual measures in terms of the embedding capacity and imperceptibility. Comparisons between the proposed approach and previous work have been implemented; it appears that the intended approach is better than the previously modified LSB algorithms, and it works against visual and statistical attacks with excellent performance achieved by using the detection error (PE). Furthermore, the results confirmed that the stego-image with high imperceptibility has reached even a payload capacity that is large and replaces twelve bits per pixel (12-bpp). Moreover, testing is confirmed in that the proposed algorithm can embed secret data efficiently with better visual quality.
Preventing data leakage by securing chat session with randomized session ID
Authors: Husin Husna Sarirah
Published: January 2022

Messaging applications have become one of the largest and most popular smartphone applications. It includes the capacity for the users to communicate between themselves via text messages, photos and files. It is necessary to safeguard all messages. Privacy is one of the biggest issues which most individuals in the world of instant messaging ignore. Although several instant messaging applications offer varying security for users, the weaknesses and danger of data assault are increasing. Not just business discussions, our data must also be safeguarded during everyday discussions since data is very sensitive for everybody, and data protection is very crucial to prevent undesired loss of information. To address these types of weaknesses and hazards associated with data attacks, we require an encrypted messaging protocol and also hide IP address method for a safe interaction. This paper's goal is to protect conversations from targeted attacker by securing the communication between user and hide IP address from unauthorized access.
Design and Development of Novel Hybrid Precoder for Millimeter-Wave MIMO System
Authors: K SRINIVAS , Srinivasulu T
Published: January 2022

Power consumption and hardware cost reduction with the use of hybrid beamforming in large-scale millimeter wave MIMO systems. The large dimensional analog precoding integrates with the hybrid beamforming based on the phase shifters including digital precoding with lower dimensionality. The reduction of Euclidean distance between the hybrid precoder and fully digital is the major problem to overcome the minimization of resultant spectral efficiency. The issue formulates as a fully digital precoder’s matrix factorization problem based on the analog RF precoder matrix and the digital baseband precoder matrix. An additional element-wise unit modulus constraint is imposed by the phase shifters on the analog RF precoder matrix. The traditional methods have a problem of performance loss in spectral efficiency. In the processing time and iteration, high complexities result in optimization algorithms. In this paper, a novel low complexity algorithm proposes which maximizes the spectral efficiency and reduces the computational processing time.
Penggunaan Media Sosial oleh Mahasiswa sebagai Upaya Sosialisasi Kegiatan Kuliah Kerja Nyata selama Pandemi COVID-19 di Kecamatan Pedurungan Semarang
Authors: Mandaka Mutiawati , Wardianto Gatoet , Affandi Ovariszar Bagus
Published: January 2022

Tujuan dari Kuliah Kerja Nyata (KKN) adalah untuk mengimplementasikan ilmu yang diterima mahasiswa di bangku kuliah serta mendidik mahasiswa untuk bisa bersosialisasi dengan warga. Sejak pandemi COVID-19 muncul tahun 2020, pelaksanaan KKN berubah mengikuti protokol yang berlaku. Hal ini mengakibatkan pelaksanaan KKN semakin terbatas. Dengan pembatasan yang cukup ketat, mahasiswa yang terjun ke lapangan sangat dibatasi. Mereka menggunakan media sosial sebagai alternatif untuk melaksanakan program kegiatan KKN selama pandemi. Tujuan pengabdian ini adalah untuk mengetahui bagaimana mahasiswa menggunakan media sosial sebagai upaya mensosialisasikan kegiatan KKN selama pandemi di Kecamatan Pedurungan. Metode yang digunakan adalah dengan deskriptif kualitatif dengan studi literatur dan survei ke lapangan dan menyebarkan kuesioner untuk mendapatkan data. Hasilnya adalah media sosial yang digunakan untuk mensosialisasikan kegiatan KKN selama pandemi paling banyak digunakan adalah media whatshap 60%, instagram 20%, youtube 15%  dan 5% menggunakan facebook. Media whatshap dianggap yang paling efektif dalam penyampaian sosialisasi kegiatan KKN di kecamatan Pedurungan.