bluuebunny/crossref_metadata_2025 huggingface dataset:
Carbon Dioxide Capture by Adsorption in a Model Hydroxy-Modified Graphene Pore
Authors: Freyre Paige , St. Pierre Emalee , Rybolt Thomas
Published: July 2023

Concerns regarding the environmental impact of increasing levels of anthropogenic carbon dioxide have led to a variety of studies examining solid surfaces for their ability to trap this greenhouse gas (GHG). Atmospheric or post-combustion carbon capture requires an efficient separation of carbon dioxide and nitrogen gas. We used the molecular mechanics MM3 parameter set (previously shown to provide good estimates of molecule–surface binding energies) to calculate theoretical surface binding energies for carbon dioxide ∆E(CO2) and nitrogen ∆E(N2). For efficient separation, differentiation of these two gas-surface adsorption energies is required. Examined structures based on graphene, carbon slit width pore, and carbon nanotube gave ∆E(CO2) to ∆E(N2) ratios of 1.7, 1.8, and 1.9, respectively. To enhance the CO2 adsorption, we developed a model graphene surface pore lined with four hydroxy groups whose orientation allowed them to form hydrogen bonds with the oxygens in CO2. Both the single-layer and double-layer versions of this pore gave significant enhancement in the ability to trap CO2 preferentially to N2. The two-layer version of this pore gave ∆E(CO2) = 73 and ∆E(N2) = 6.8 kJ/mol. The one- and two-layer versions of this novel pore averaged a ∆E(CO2) to ∆E(N2) ratio of 12.
The Application of Z-Numbers in Fuzzy Decision Making: The State of the Art
Authors: Alam Nik Muhammad Farhan Hakim Nik Badrul , Ku Khalif Ku Muhammad Naim , Jaini Nor Izzati , Gegov Alexander
Published: July 2023

A Z-number is very powerful in describing imperfect information, in which fuzzy numbers are paired such that the partially reliable information is properly processed. During a decision-making process, human beings always use natural language to describe their preferences, and the decision information is usually imprecise and partially reliable. The nature of the Z-number, which is composed of the restriction and reliability components, has made it a powerful tool for depicting certain decision information. Its strengths and advantages have attracted many researchers worldwide to further study and extend its theory and applications. The current research trend on Z-numbers has shown an increasing interest among researchers in the fuzzy set theory, especially its application to decision making. This paper reviews the application of Z-numbers in decision making, in which previous decision-making models based on Z-numbers are analyzed to identify their strengths and contributions. The decision making based on Z-numbers improves the reliability of the decision information and makes it more meaningful. Another scope that is closely related to decision making, namely, the ranking of Z-numbers, is also reviewed. Then, the evaluative analysis of the Z-numbers is conducted to evaluate the performance of Z-numbers in decision making. Future directions and recommendations on the applications of Z-numbers in decision making are provided at the end of this review.
Smart Wearable to Prevent Injuries in Amateur Athletes in Squats Exercise by Using Lightweight Machine Learning Model
Authors: Arciniega-Rocha Ricardo P. , Erazo-Chamorro Vanessa C. , Rosero-Montalvo Paúl D. , Szabó Gyula
Published: July 2023

An erroneous squat movement might cause different injuries in amateur athletes who are not experts in workout exercises. Even when personal trainers watch out for the athletes’ workout performance, light variations in ankles, knees, and lower back movements might not be recognized. Therefore, we present a smart wearable to alert athletes whether their squats performance is correct. We collect data from people experienced with workout exercises and from learners, supervising personal trainers in annotation of data. Then, we use data preprocessing techniques to reduce noisy samples and train Machine Learning models with a small memory footprint to be exported to microcontrollers to classify squats’ movements. As a result, the k-Nearest Neighbors algorithm with k = 5 achieves an 85% performance and weight of 40 KB of RAM.
Exploitation of Vulnerabilities: A Topic-Based Machine Learning Framework for Explaining and Predicting Exploitation
Authors: Charmanas Konstantinos , Mittas Nikolaos , Angelis Lefteris
Published: July 2023

Security vulnerabilities constitute one of the most important weaknesses of hardware and software security that can cause severe damage to systems, applications, and users. As a result, software vendors should prioritize the most dangerous and impactful security vulnerabilities by developing appropriate countermeasures. As we acknowledge the importance of vulnerability prioritization, in the present study, we propose a framework that maps newly disclosed vulnerabilities with topic distributions, via word clustering, and further predicts whether this new entry will be associated with a potential exploit Proof Of Concept (POC). We also provide insights on the current most exploitable weaknesses and products through a Generalized Linear Model (GLM) that links the topic memberships of vulnerabilities with exploit indicators, thus distinguishing five topics that are associated with relatively frequent recent exploits. Our experiments show that the proposed framework can outperform two baseline topic modeling algorithms in terms of topic coherence by improving LDA models by up to 55%. In terms of classification performance, the conducted experiments—on a quite balanced dataset (57% negative observations, 43% positive observations)—indicate that the vulnerability descriptions can be used as exclusive features in assessing the exploitability of vulnerabilities, as the “best” model achieves accuracy close to 87%. Overall, our study contributes to enabling the prioritization of vulnerabilities by providing guidelines on the relations between the textual details of a weakness and the potential application/system exploits.
Poverty Traps in Online Knowledge-Based Peer-Production Communities
Authors: Vargo Andrew , Tag Benjamin , Blakely Chris , Kise Koichi
Published: July 2023

Online knowledge-based peer-production communities, like question and answer sites (Q&A), often rely on gamification, e.g., through reputation points, to incentivize users to contribute frequently and effectively. These gamification techniques are important for achieving the critical mass that sustains a community and enticing new users to join. However, aging communities tend to build “poverty traps” that act as barriers for new users. In this paper, we present our investigation of 32 domain communities from Stack Exchange and our analysis of how different subjects impact the development of early user advantage. Our results raise important questions about the accessibility of knowledge-based peer-production communities. We consider the analysis results in the context of changing information needs and the relevance of Q&A in the future. Our findings inform policy design for building more equitable knowledge-based peer-production communities and increasing the accessibility to existing ones.
Field and Laboratory Observations on the Biology of Aceria angustifoliae with Emphasis on Emergence of Overwintering Mites
Authors: Lotfollahi Parisa , Mehri-Heyran Hosein , Azimi Solmaz , de Lillo Enrico
Published: July 2023

Data on the life strategy of A. angustifoliae (population fluctuation in buds and on leaves, emergence and migration to the overwintering sites), as well as its temperature-dependent emergence from overwintering sites at constant temperatures, were determined. The eriophyid mite overwintered into buds and the density of active mites inside them from winter 2017 to spring 2018 was higher than that in winter 2018–spring 2019. In the second half of March 2018 and in winter 2018–spring 2019, the mite density inside the buds decreased gradually with a peak of emergence occurring at the beginning of plant blossoming. Population density on leaves increased in summer, reaching a higher and later peak in 2018, and gradually decreased in autumn with mites migrating to overwintering sites. A lower developmental threshold of 4.5 °C was calculated. About half of the mite population was estimated to emerge from the overwintering sites at an accumulation of degree days ranging, on average, between 85.5 (at 20 °C) and 104.4 (at 10 °C) degree days above the assessed threshold.
A New, Non-Invasive Methodology for the Molecular Identification of Adult Sarcophagidae from Collections
Authors: Giordani Giorgia , Whitmore Daniel , Vanin Stefano
Published: July 2023

Correct species identification is the cornerstone of all scientific studies that involve insects. Alongside traditional morphological identification techniques, molecular identification based on the characterization and analysis of specific mitochondrial or nuclear gene regions is becoming commonplace. Despite the good results that can be achieved, DNA extraction usually involves invasive techniques that lead to the partial or total destruction of specimens. In this work, a non-invasive DNA extraction technique is described. The technique was tested on the abdomens of dry-preserved Sarcophagidae (Diptera) specimens collected between 1889 and 2015. This allowed for the correct identification of species without impairing diagnostic morphological structures useful for further studies.
Essential Oils and Their Components Control Behaviour of Yellow Mealworm (Tenebrio molitor) Larvae
Authors: Bumbulytė Gabrielė , Būdienė Jurga , Būda Vincas
Published: July 2023

Beetle Tenebrio molitor L. (Coleoptera, Tenebrionidae) is a well-known pest of grain and flour in food stores and grocery shops. Recently, commercial cultivation of the insect was started for human food and animal feed. Behaviour control of this insect using natural repellents is promising both for grain protection and commercial cultivation. We analysed if natural products of plant origin, namely essential oils (EOs), could be used for this purpose. Behavioural tests were performed using EOs of six plants: thymus (Thymus vulgaris), eucalyptus (Eucalyptus globulus), spearmint (Mentha spicata), lavandin (Lavandula × hybrida), East-Indian lemongrass (Cymbopogon flexuosus), and clove (Eugenia caryophyllus). The most effective repellent for mealworm larvae was EO of spearmint, moderate activity showed that of clove and the least repellent were EOs of lemongrass thymus and lavandin. EO of eucalyptus caused almost no or very low effect. Six of the most abundant compounds of the EOs were selected for testing. The most effective single compounds were terpinene-4-ol and carvone, low-effective cis-sabinene hydrates and those of no significant activity were limonene, myrcene and γ-terpinene.
Performance Analysis of Harmonic-Reduced Modified PUC Multi-Level Inverter Based on an MPC Algorithm
Authors: Krishnamoorthy Umapathi , Pitchaikani Ushaa , Rusu Eugen , Fayek Hady H.
Published: July 2023

Renewable and distributed energy generation includes wind turbines, fuel cells, solar cells, and batteries. These distributed energy sources need special power converters in order to connect them to the grid and make the generated power available for public use. Solar energy is the most readily available energy source; hence, if utilized properly, it can power up both domestic and industrial loads. Solar cells produce DC power, and this should be converted to an AC source with the help of inverters. A multi-level inverter for an application is selected based on a trade-off between cost, complexity, losses, and total harmonic distortion (THD). A packed U-cell (PUC) topology is composed of power switches and voltage sources connected in a series-parallel fashion. This basic unit can be extended to a greater number of output voltage levels. The significance of this design is the reduced use of power switches, gate drivers, protection circuits, and capacitors. The converter presented in this paper is a 31-level topology switched by a variable switching frequency-based model predictive controller that helps in achieving optimal output with reduced harmonics to a great extent. The gate driver circuit is also optimized in terms of power consumption and size complexity. A comparison of the 9-level and the 31-level PUC inverters is carried out to study the impact of the number of levels on the total harmonic distortion. The simulation results depict that the total harmonic distortion (THD) for a nominal modulation index of 0.8 is 11.54% and 3.27% for the 9-level multi-level inverter (MLI) and the 31-level modified packed U-cell multi-level inverter (MPUC-MLI), respectively. The reduction in THD is attributed to the increased number of steps in the output when using the model predictive controller.
Comparison of Two Techniques Performing the Supine-to-Sitting Postural Change in Patients with Sternotomy
Authors: Giardini Marica , Guenzi Marco , Arcolin Ilaria , Godi Marco , Pistono Massimo , Caligari Marco
Published: July 2023

Patients with sternotomy are advised to follow sternal precautions to avoid the risk of sternal complications. However, there are no standard recommendations, in particular to perform the supine-to-sitting postural change, where sternal asymmetrical force may be applied. The aim of this study was to compare the rotational movement and the use of a tied rope (individual device for supine-to-sitting, “IDSS”) to perform the supine-to-sitting postural change. A total of 92 patients (26% female) admitted to a rehabilitative post-surgery ward with sternotomy were assessed for sternal instability. Levels of pain and perceived effort during the two modalities of postural change and at rest were assessed. Patients reported higher values of pain and perceived effort (both p < 0.0005) during rotational movement with respect to the use of the IDSS. Moreover, patients with sternal instability (14%) and female patients with macromastia (25%) reported higher pain than those stable or without macromastia (both p < 0.05). No other risk factors were associated with pain. Thus, the IDSS seems to reduce the levels of pain and perceived effort during the supine-to-sitting postural change. Future studies with quantitative assessments are required to suggest the adoption of this technique, mostly in patients with high levels of pain or with sternal instability.
Interaction of Diamine Oxidase with Psychostimulant Drugs for ADHD Management
Authors: Tobajas Yaiza , Alemany-Fornés Marc , Samarra Iris , Romero-Giménez Jordi , Tintoré Maria , del Pino Antoni , Canela Núria , del Bas Josep M. , Ortega-Olivé Nàdia , de Lecea Carlos , Escoté Xavier
Published: July 2023

Histamine intolerance occurs when there is an imbalance between histamine production and the capacity for histamine degradation. Diamine oxidase (DAO) is the main enzyme for the catabolism of ingested histamine degradation in the gastrointestinal tract and its deficiency has been linked to allergy-like symptoms. Psychostimulant drugs are commonly used to treat Attention Deficit Hyperactivity Disorder (ADHD), but their interaction with DAO is not well characterized. In this work, we evaluated the effects of psychostimulant drugs (methylphenidate and lisdexamfetamine) on in vitro DAO activity and in the human cell line of enterocytes (Caco-2), evaluating DAO expression (mRNA and protein) and DAO activity. Methylphenidate and lisdexamfetamine did not repress the in vitro DAO activity. In addition, in Caco-2 cells, lisdexamfetamine promoted a strong upregulation of DAO mRNA levels, whereas methylphenidate tended to induce DAO activity. To sum up, methylphenidate and lisdexamfetamine treatments do not reduce DAO activity. These findings could be useful for physicians prescribing these two drugs to ADHD patients affected by DAO deficiency.
Comparison of Blood and Blood Product Transfusion in COVID-19 and Non-COVID-19 Patients Requiring Extracorporeal Membrane Oxygenation for Severe Respiratory Failure
Authors: Fernando Malindra C. , Hayes Tim , Besser Martin , Falter Florian
Published: July 2023

COVID-19 has resulted in an exponential increase in patients with severe respiratory failure requiring extracorporeal membrane oxygenation (ECMO). Patients on ECMO regularly require high volumes of blood and blood products but, so far, there has been no comparison of transfusion requirements between COVID-19 and non-COVID-19. Using electronic patient records at two major UK ECMO centres, Royal Papworth Hospital and University Hospital South Manchester, we reviewed the transfusion requirements of patients requiring ECMO between January 2019 to December 2021. A total of 271 patients, including 168 COVID-19 patients were available for analysis. Since COVID-19 patients spent almost twice as long on ECMO (27.1 vs. 14.16 days, p ≤ 0.0001) we indexed transfusion in both groups to days on ECMO to allow comparison. COVID-19 patients required less red blood cells (RBC) per day (0.408 vs. 0.996, p = 0.0005) but more cryoprecipitate transfusions (0.117 vs. 0.106, p = 0.022) compared to non-COVID-19 patients. COVID-19 patients had more than double the mortality of non-COVID-19 patients (47% vs. 20.4%, p = 0.0001) and those who died during the study period had higher platelet transfusion requirements (p = 0.007) than their non-COVID-19 counterparts. Transfusion requirements and coagulopathy differ between COVID-19 and non-COVID-19 patients. The distinctly different transfusion patterns between the two groups remain difficult to interpret, but further investigations may help explain the haematological aspects of severe COVID-19 infection.
Prospects for Precision Medicine in Acute Myocardial Infarction: Patient-Level Insights into Myocardial Injury and Repair
Authors: Alkhalil Mohammad , De Maria Giovanni Luigi , Akbar Naveed , Ruparelia Neil , Choudhury Robin P.
Published: July 2023

The past decade has seen a marked expansion in the understanding of the pathobiology of acute myocardial infarction and the systemic inflammatory response that it elicits. At the same time, a portfolio of tools has emerged to characterise some of these processes in vivo. However, in clinical practice, key decision making still largely relies on assessment built around the timing of the onset of chest pain, features on electrocardiograms and measurements of plasma troponin. Better understanding the heterogeneity of myocardial injury and patient-level responses should provide new opportunities for diagnostic stratification to enable the delivery of more rational therapies. Characterisation of the myocardium using emerging imaging techniques such as the T1, T2 and T2* mapping techniques can provide enhanced assessments of myocardial statuses. Physiological measures, which include microcirculatory resistance and coronary flow reserve, have been shown to predict outcomes in AMI and can be used to inform treatment selection. Functionally informative blood biomarkers, including cellular transcriptomics; microRNAs; extracellular vesicle analyses and soluble markers, all give insights into the nature and timing of the innate immune response and its regulation in acute MI. The integration of these and other emerging tools will be key to developing a fuller understanding of the patient-level processes of myocardial injury and repair and should fuel new possibilities for rational therapeutic intervention.
Does Robot Assisted Laparoscopy (RAL) Have an Advantage in Preservation of Ovarian Reserve in Endometriosis Surgery? Comparison of Single-Port Access (SPA) RAL and SPA Laparoscopy
Authors: Kang Jun-Hyeok , Chang Chi-Son , Noh Joseph J. , Kim Tae-Joong
Published: July 2023

The purpose of this study was to compare single-port access (SPA) laparoscopy and SPA robot assisted laparoscopy (RAL) for endometriosis with respect to ovarian reserve preservation and surgical outcomes. Clinical factors affecting any reduction in ovarian function after surgery were also evaluated. Patients with endometriosis who underwent SPA laparoscopy (n = 87) or RAL (n = 78) were retrospectively reviewed. Patients’ baseline characteristics, including the severity of endometriosis and surgical outcomes including surgical complexity, were collected. To assess the preservation of ovarian reserve after surgery, serum anti-Müllerian hormone (AMH) levels before surgery, at two weeks, and at three months after surgery were collected. Age, ovarian cyst size, location of cyst, complexity of surgery, and the severity of endometriosis were associated with the reduction in AMH levels after surgery. The severity of endometriosis was higher in the RAL group than in the SPA group. There were no significant differences in other clinical baseline characteristics, including preoperative AMH levels. For surgical outcomes, radical surgery was more frequently performed in the RAL group. In univariate and multivariate linear regression analyses, age, ovarian cyst size, location of cyst, complexity of surgery, and the severity of endometriosis were associated with the reduction in AMH levels after surgery. Incorporating surgical approaches and risk factors for postoperative ovarian function decrease, RAL was more beneficial than SPA laparoscopy for the preservation of ovarian reserve in patients with mild endometriosis (stage I/II) (postoperative 3 month AMH reduction rate (%), SPA laparoscopy vs. RAL, 33.51 ± 19.98 vs. 23.58 ± 14.98, p = 0.04) and in patients who underwent non-complex surgery (postoperative 3 month AMH reduction rate (%), SPA laparoscopy vs. RAL, 37.89 ± 22.37 vs. 22.37 ± 17.49, p = 0.022). SPA RAL may have advantages over SPA laparoscopy in ovarian function preservation, especially in patients with mild endometriosis and patients who have undergone a non-complex surgery.
Exploring the Relationship between Anti-VEGF Therapy and Glaucoma: Implications for Management Strategies
Authors: Daka Qëndresë , Špegel Nina , Atanasovska Velkovska Makedonka , Steblovnik Tjaša , Kolko Miriam , Neziri Burim , Cvenkel Barbara
Published: July 2023

A short-term increase in intraocular pressure (IOP) is a common side effect after intravitreal anti-VEGF therapy, but a sustained increase in IOP with the development of secondary glaucoma has also been reported in some studies after repeated intravitreal anti-VEGF injections. The aim of this review is to present and discuss the possible pathophysiological mechanisms and factors contributing to a sustained rise in IOP, as well as treatment strategies for patients at risk. Close monitoring and adjustable IOP-lowering treatment are recommended for high-risk patients, including those with glaucoma, angle-closure anomalies, ocular hypertension or family history of glaucoma; patients receiving a high number of injections or at shorter intervals; and patients with capsulotomy. Strategies are needed to identify patients at risk in a timely manner and to prevent sustained elevation of IOP.
Patient Perspectives on Digital Interventions to Manage Heart Failure Medications: The VITAL-HF Pilot
Authors: Samsky Marc D. , Leverty Renee , Gray James M. , Davis Alexandra , Fisher Brett , Govil Ashul , Stanis Tom , DeVore Adam D.
Published: July 2023

Use of guideline-directed medical therapy (GDMT) for treatment of heart failure with reduced ejection fraction (HFrEF) remains unacceptably low. The purpose of this study was to determine whether a digital health tool can augment GDMT for patients with HFrEF. Participants ≥ 18 years old with symptomatic HFrEF (left ventricular ejection fraction ≤ 40%) and with access to a mobile phone with internet were included. Participants were given a blood pressure cuff, instructed in its use, and given regular symptom surveys via cell-phone web-link. Data were transmitted to the Story Health web-based platform, and automated alerts were triggered based on pre-specified vital sign and laboratory data. Health coaches assisted patients with medication education, pharmacy access, and lab access through text messages and phone calls. GDMT titration plans were individually created in the digital platform by local clinicians based on entry vitals and labs. Twelve participants enrolled and completed the study. The median age and LVEF were 52.5 years (IQR, 46.5–63.5) and 25% (IQR, 22.5–35.5), respectively. There were 10 GDMT initiations, 52 up-titrations, and 13 down-titrations. Five participants engaged in focus-group interviews following study completion to understand first-hand perspectives regarding the use of digital tools to manage GDMT. Participants expressed comfort knowing that there were clinicians regularly reviewing their data. This alleviated concerns of uncertainty in daily living, led to an increased feeling of security, and empowered patients to understand decision-making regarding GDMT. Frequent medication changes, and the associated financial impact, were common concerns. Remote titration of GDMT for HFrEF is feasible and appears to be a patient-centered approach to care.
The Effect of Transcutaneous Electrotherapy on Lumbar Range of Motion and Paraspinal Muscle Characteristics in Chronic Low Back Pain Patients: A Systematic Review and Meta-Analysis
Authors: Wolfe Daniel , Rosenstein Brent , Fortin Maryse
Published: July 2023

Chronic low back pain (CLBP) affects paraspinal muscle size, quality (e.g., fatty infiltration), range of motion (ROM), and strength. Although transcutaneous electrotherapies are used to treat CLBP, their effects on paraspinal-related outcomes are not fully known. The aim of this systematic review and meta-analysis was to assess the overall effect of transcutaneous electrotherapies on trunk/lumbar ROM, paraspinal muscle morphology, and trunk muscle function (including strength and endurance) in CLBP patients. A systematic search of four databases and two study registers was conducted between 1 February 2022 and 15 September 2022. Two reviewers were responsible for screening and data extraction. Of the 3939 independent records screened, 10 were included in the systematic review and 2 in the meta-analysis. The results suggest there is limited evidence that both EMS and EMS plus exercise are superior to passive and active controls, respectively, for improving trunk muscle endurance. There is limited evidence that neither TENS nor mixed TENS are superior to controls for improving trunk muscle endurance. There is limited evidence that NMES is superior to passive controls for improving trunk muscle strength. The effect of transcutaneous electrotherapy on the other investigated outcomes was inconclusive. Future transcutaneous electrotherapy studies should focus on paraspinal-based outcomes that are under-studied.
Single versus Dual-Operator Approaches for Percutaneous Coronary Interventions within Chronic Total Occlusion—An Analysis of 27,788 Patients
Authors: Januszek Rafał , De Luca Giuseppe , Siłka Wojciech , Bryniarski Leszek , Malinowski Krzysztof Piotr , Surdacki Andrzej , Wańha Wojciech , Bartuś Stanisław , Piotrowska Aleksandra , Bartuś Krzysztof , Pytlak Kamil , Siudak Zbigniew
Published: July 2023

(1) Background: Since the treatment of chronic total occlusion (CTO) with percutaneous coronary intervention (PCI) is associated with high procedural complexity, it has been suggested to use a multi-operator approach. This study was aimed at evaluating the procedural outcomes of single (SO) versus dual-operator (DO) CTO-PCI approaches. (2) Methods: This retrospective analysis included data from the Polish Registry of Invasive Cardiology Procedures (ORPKI), collected between January 2014 and December 2020. To compare the DO and SO approaches, propensity score matching was introduced with equalized baseline features. (3) Results: The DO approach was applied in 3604 (13%) out of 27,788 CTO-PCI cases. Patients undergoing DO CTO-PCI experienced puncture-site bleeding less often than the SO group (0.1% vs. 0.3%, p = 0.03). No differences were found in the technical success rate (successful revascularization with thrombolysis in myocardial infarction flow grade 2/3) of the SO (72.4%) versus the DO approach (71.2%). Moreover, the presence of either multi-vessel (MVD) or left main coronary artery disease (LMCA) (odds ratio (OR), 1.67 (95% confidence interval (CI), 1.20–2.32); p = 0.002), as well as lower annual and total operator volumes of PCI and CTO-PCI, could be noted as factors linked with the DO approach. (4) Conclusions: Due to the retrospective character, the findings of this study have to be considered only as hypothesis-generating. DO CTO-PCI was infrequent and was performed on patients who were more likely to have LMCA lesions or MVD. Operators collaboratively performing CTO-PCIs were more likely to have less experience. Puncture-site bleeding occurred less often in the dual-operator group; however, second-operator involvement had no impact on the technical success of the intervention.
Characteristics of Preoperative Arteriosclerosis Evaluated by Cardio-Ankle Vascular Index in Patients with Osteoarthritis before Total Knee Arthroplasty
Authors: Ishii Yoshinori , Noguchi Hideo , Sato Junko , Takahashi Ikuko , Ishii Hana , Ishii Ryo , Ishii Kei , Ishii Kai , Toyabe Shin-ichi
Published: July 2023

Purpose: Cardiovascular disease (CVD) is a major risk factor for mortality in patients with osteoarthritis, and comorbidities increase postoperative complications after total knee arthroplasty (TKA). Arteriosclerosis plays a main role in hemodynamic dysfunction and CVD; however, arteriosclerosis has not been preoperatively evaluated before TKA using the cardio-ankle vascular index (CAVI). In this study, we evaluated the degree of preoperative arteriosclerosis using the CAVI in patients undergoing TKA, as well as its correlations with several preoperative patient factors. Methods: Arteriosclerosis was evaluated in 209 consecutive patients (251 knees) with osteoarthritis who underwent TKA at our institution between May 2011 and June 2022. The CAVI was measured in the supine position 1 day before TKA, and the correlations between the CAVI and several clinical factors were analyzed. Results: The CAVI was normal in 62 knees (25%), borderline in 71 knees (28%), and abnormal in 118 knees (47%). Univariate analysis revealed a moderate positive correlation between preoperative CAVI and age (r = 0.451, p < 0.001) and a weak negative correlation between preoperative CAVI and body weight (r = −0.306, p < 0.001) and body mass index (BMI) (r = −0.319, p < 0.001). Multivariate analysis showed that age (β = 0.349, p < 0.001) and BMI (β = −0.235, p < 0.001) were significantly correlated with preoperative CAVI. Conclusion: Arteriosclerosis should be carefully managed intraoperatively and postoperatively in patients with osteoarthritis undergoing TKA, particularly in older patients and patients with a low BMI.
Role of Selected Circulating Tumor Biomarkers in Patients with Skeletal Metastatic Pancreatic Neuroendocrine Neoplasms
Authors: Rosiek Violetta , Janas Ksenia , Witkowska Magdalena , Kos-Kudła Beata
Published: July 2023

We investigated the diagnostic capacity of selected circulating biomarkers (CBMs) for the early detection of bone metastasis (BMets) in patients with pancreatic neuroendocrine neoplasms (PanNENs). A total of 115 patients with PanNENs and 40 controls were enrolled. We measured the serum levels of ferritin, cytokeratin 18 (CY18), CA19-9, CA125, AFP, CEA, and beta-2 microglobulin (B2M). A total of eight PanNEN patients developed BMets, and one hundred seven remained BMets-free. We observed a significantly higher level of CA125 and CY18 in BMets patients vs. non-BMets patients (p = 0.01 and p = 0.04, respectively). CA125, CY18, and B2M area under receiver operator characteristic (AUROC) analyses differentiated both patients groups; CA125 area under the curve (AUC) 0.77, p < 0.01; CY18 AUC data were 0.72, p = 0.03, and B2M AUC 0.67, p = 0.02. On the basis of CBM metrics in both subgroups, we reached a sensitivity/specificity for CA125 of 75/76%; for CY18 of 75/69%, for B2M of 100/50%, for CA125, and the CY18 combination of 93/90%, respectively. According to current results, CA125 and CY18 seem to have the potential capacity as fair biomarkers for BMets detection, despite the small number of cases. Further studies are warranted in the larger PanNEN patient group.
Interventional Radiology for High-Flow Aneurysm of the Pancreaticoduodenal Arcades with Median Arcuate Ligament Syndrome: Review of 14 Patients
Authors: Siauve Valentin , Chevallier Olivier , Mazit Amin , Falvo Nicolas , Comby Pierre-Olivier , Loffroy Romaric
Published: July 2023

Transarterial embolization (TAE) for high-flow pancreaticoduodenal artery (PDA) aneurysms in patients with celiac-trunk stenosis by the median arcuate ligament (MAL) has been found effective both after rupturing and to prevent rupture. The objective was to describe the TAE techniques used and their effectiveness in excluding PDA aneurysms due to MAL syndrome. This single-center retrospective study done at the Dijon-Bourgogne University Hospital included all patients treated by TAE in 2010–2022 for ruptured or unruptured high-flow PDA aneurysms caused by MAL syndrome. We identified 14 patients (7 women and 7 men; mean age, 64 years). Packing and trapping techniques were used alone or together. Occlusion was with microcoils, co-polymer, or cyanoacrylate glue, used separately or combined. Technical success was achieved in 13 (93%) patients. Clinical success was achieved in 12 (86%) patients. One major and two minor complications were recorded within the first 30 days. No complications occurred after 30 days. Follow-up ranged from 1 to 84 months. No cases of aneurysm recanalization have been recorded to date. TAE had high technical and clinical success rates in our patients with unruptured or ruptured PDA aneurysms due to MAL syndrome.
Experimental Investigation of Aloe Vera-Treated False Banana (Ensete Ventricosum) Fibre-Reinforced Polypropylene Composite
Authors: Shimels Hailu G. , Ketema Sisay , Trzepieciński Tomasz , Batu Temesgen
Published: July 2023

This research work investigates the effects of the concentration and treatment of chopped false banana (Ensete ventricosum) fibres on the mechanical properties of a polypropylene matrix. The chopped false banana fibres (FBFs) were modified using Aloe Vera gel following treatment with 5% NaOH for 12 h at room temperature, with 1% acetic acid used to neutralise the remaining NaOH. FBF-reinforced polypropylene composite plates were then manufactured with 10, 20, 30, and 40 wt.% of chopped FBF. The mechanical properties were investigated using the compressive, impact, and three-point bending tests. Regarding the mechanical properties of the FBF-reinforced polypropylene composites, it was found that they have a maximum average compressive strength of 17.2 MPa. A maximum bending strength of 12.109 MPa was found for the Aloe Vera gel-treated composite with 30 wt.% of FBF. The maximum average compressive strength for this composite was 17.19 MPa. A maximum bending strength of 9.97 MPa for untreated composites was recorded for the composite with 10 wt.% of FBF. Finally, Aloe Vera-treated FBF-reinforced composites have better mechanical properties than untreated ones. The mechanical properties of Aloe Vera-treated FBF-reinforced polypropylene composites, as determined via impact, compressive and flexural tests, were superior for composites with 30 wt.% of FBF.
Effect of ECAP on Microstructure, Mechanical Properties, Corrosion Behavior, and Biocompatibility of Mg-Ca Alloy Composite
Authors: Huang Song-Jeng , Wang Chih-Feng , Subramani Murugan , Fan Fang-Yu
Published: July 2023

This study investigates the effects of incorporating MgO into magnesium–calcium (Mg-Ca) alloy composites and subjecting them to the equal channel angular pressing (ECAP) process on the resulting mechanical and corrosive properties, as well as biocompatibility. Initially, the incorporation of MgO into the Mg-Ca alloy composites did not yield significant improvements in grain refinement, tensile strength, or corrosion rate reduction, despite exhibiting improved biocompatibility. However, upon subjecting the Mg-Ca-MgO alloy composites to the ECAP process, noteworthy outcomes were observed. The ECAP process resulted in substantial grain refinement, leading to significant improvements in tensile strength. Furthermore, a marked decrease in corrosion rate was observed, indicating enhanced corrosion resistance. Additionally, the biocompatibility of the Mg-Ca-MgO alloy composites improved after undergoing the ECAP process. These findings highlight the synergistic effect of incorporating MgO and employing the ECAP process, providing valuable insights into the development of advanced magnesium-based materials with superior mechanical properties, reduced corrosion rates, and improved biocompatibility.
Decontaminative Properties of Cold Atmospheric Plasma Treatment on Collagen Membranes Used for Guided Bone Regeneration
Authors: Gülses Aydin , Dohrmann Lina , Aktas Oral Cenk , Wagner Juliane , Veziroglu Salih , Tjardts Tim , Hartig Torge , Liedtke Kim Rouven , Wiltfang Jörg , Acil Yahya , Flörke Christian
Published: July 2023

Background cold atmospheric plasma (CAP) is known to be a surface-friendly yet antimicrobial and activating process for surfaces such as titanium. The aim of the present study was to describe the decontaminating effects of CAP on contaminated collagen membranes and their influence on the properties of this biomaterial in vitro. Material and Methods: A total of n = 18 Bio-Gide® (Geistlich Biomaterials, Baden-Baden, Germany) membranes were examined. The intervention group was divided as follows: n = 6 membranes were treated for one minute, and n = 6 membranes were treated for five minutes with CAP using kINPen® MED (neoplas tools GmbH, Greifswald, Germany) with an output of 5 W, respectively. A non-CAP-treated group (n = 6) served as the control. The topographic alterations were evaluated via X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM). Afterward, the samples were contaminated with E. faecalis for 6 days, and colony-forming unit (CFU) counts and additional SEM analyses were performed. The CFUs increased with CAP treatment time in our analyses, but SEM showed that the surface of the membranes was essentially free from bacteria. However, the deeper layers showed remaining microbial conglomerates. Furthermore, we showed, via XPS analysis, that increasing the CAP time significantly enhances the carbon (carbonyl group) concentration, which also correlates negatively with the decontaminating effects of CAP. Conclusions: Reactive carbonyl groups offer a potential mechanism for inhibiting the growth of E. faecalis on collagen membranes after cold atmospheric plasma treatment.
Self-Efficacy and the Digit Ratio in a Group of Sports University Students
Authors: Massimino Simona , Rinella Sergio , Guerrera Claudia Savia , Di Corrado Donatella , Astuto Romina , Sorbello Alessia , Reina Francesca , Perciavalle Vincenzo , Buscemi Andrea , Coco Marinella
Published: July 2023

Self-efficacy is one’s awareness of being able to cope optimally with different situations. Perceived self-efficacy is a belief that closely involves emotional and personological functioning. In fact, when one perceives oneself as capable, the likelihood of success increases significantly. The aim of this research was to verify a possible correlation between self-efficacy and the Digit Ratio (2D:4D), referred to as prenatal androgen levels, and whether these correlate with some psychological variables, considering possible gender differences. This study involved 56 sports university students, whose 2D:4D ratio was calculated. Moreover, self-assessment questionnaires: the Self-efficacy Scale (SES), the Big Five Questionnaire-2 (BFQ-2), the Profile of Mood State (POMS), the State–Trait Anxiety Inventory Form Y (STAI-Y) and the Emotional Regulation Questionnaire (ERQ) were administered. The data show that the perceived levels of self-efficacy seem to be influenced by an innate predisposition linked to prenatal androgen values to which the subjects were exposed during uterine life (2D:4D). This negative correlation indicates that the higher the value of the digit ratio, the more likely it is that the level of perceived self-efficacy will be lower. Finally, the degree of perceived self-efficacy also seems to depend on the levels of subjective anxiety, understood both as a personological disposition and a contingent condition, and the latter also seems to be influenced by prenatal androgen levels, particularly in women.
Contact Temperature Measurements on Hybrid Aluminum–Steel Workpieces in a Cross-Wedge Rolling Process
Authors: Merkel Paulina , Kruse Jens , Kriwall Mareile , Behrens Bernd-Arno , Stonis Malte
Published: July 2023

The Collaborative Research Center 1153 is investigating a novel process chain for manufacturing high-performance hybrid components. The combination of aluminum and steel can reduce the weight of components and lead to lower fuel consumption. During the welding of aluminum and steel, a brittle intermetallic phase is formed that reduces the service life of the component. After welding, the workpiece is heated inhomogeneously and hot-formed in a cross-wedge rolling process. Since the intermetallic phase grows depending on the temperature during hot forming, temperature control is of great importance. In this paper, the possibility of process-integrated contact temperature measurement with thin-film sensors is investigated. For this purpose, the initial temperature distribution after induction heating of the workpiece is determined. Subsequently, cross-wedge rolling is carried out, and the data of the thin-film sensors are compared to the temperature measurements after heating. It is shown that thin-film sensors inserted into the tool are capable of measuring surface temperatures even at a contact time of 0.041 s. The new process monitoring of the temperature makes it possible to develop a better understanding of the process as well as to further optimize the temperature distribution. In the long term, knowledge of the temperatures in the different materials also makes it possible to derive quality characteristics as well as insights into the causes of possible process errors (e.g., fracture of the joining zone).
A Machine Learning-Based Approach for Multi-AGV Dispatching at Automated Container Terminals
Authors: Gao Yinping , Chen Chun-Hsien , Chang Daofang
Published: July 2023

The dispatching of automated guided vehicles (AGVs) is essential for efficient horizontal transportation at automated container terminals. Effective planning of AGV transportation can reduce equipment energy consumption and shorten task completion time. Multiple AGVs transport containers between storage blocks and vessels, which can be regarded as the supply sides and demand points of containers. To meet the requirements of shipment in terms of timely and high-efficient delivery, multiple AGVs should be dispatched to deliver containers, which includes assigning tasks and selecting paths. A contract net protocol (CNP) is employed for task assignment in a multiagent system, while machine learning provides a logical alternative, such as Q-learning (QL), for complex path planning. In this study, mathematical models for multi-AGV dispatching are established, and a QL-CNP algorithm is proposed to tackle the multi-AGV dispatching problem (MADP). The distribution of traffic load is balanced for multiple AGVs performing tasks in the road network. The proposed model is validated using a Gurobi solver with a small experiment. Then, QL-CNP is used to conduct experiments with different sizes. The other algorithms, including Dijkstra, GA, and PSO, are also compared with the QL-CNP algorithm. The experimental results demonstrate the superiority of the proposed QL-CNP when addressing the MADP.
A COLREGs-Compliant Ship Collision Avoidance Decision-Making Support Scheme Based on Improved APF and NMPC
Authors: Li Haibin , Wang Xin , Wu Tianhao , Ni Shengke
Published: July 2023

In this paper, combined with the improved artificial potential field (IAPF) method and the nonlinear model predictive control (NMPC) algorithm, a collision avoidance decision-making support scheme considering ship maneuverability and the International Regulations for Preventing Collisions at Sea (COLREGs) is proposed. First, to comply with the requirements of COLREGs, an improved repulsive potential field is presented for different encounter scenarios when the ship detects the risk of collision, and the coordinated ship domain is applied to provide safety criteria for collision avoidance. Then, by transforming the MMG model to a discrete-time nonlinear system, the NMPC is utilized to predict the future state of the ship according to the current state, and the IAPF method is incorporated to calculate the potential field in each future state as the objective function. Following this approach, the action taken to avoid collision is more effective, the ship motion in avoiding collision is more accurate, and the collision avoidance decision making is more reasonable. Finally, two simulation examples of multi-ship encounter scenarios are applied to illustrate the merits and effectiveness of the proposed collision avoidance decision-making support scheme.
Cross-Coupled Dynamics and MPA-Optimized Robust MIMO Control for a Compact Unmanned Underwater Vehicle
Authors: Tanveer Ahsan , Ahmad Sarvat Mushtaq
Published: July 2023

A compact, 3-degrees-of-freedom (DoF), low-cost, remotely operated unmanned underwater vehicle (UUV), or MicroROV, is custom-designed, developed, instrumented, and interfaced with a PC for real-time data acquisition and control. The nonlinear equations of motion (EoM) are developed for the under-actuated, open-frame, cross-coupled MicroROV utilizing the Newton-Euler approach. The cross-coupling between heave and yaw motion, an important dynamic of a class of compact ROVs that is barely reported, is investigated here. This work is thus motivated towards developing an understanding of the physics of the highly coupled compact ROV and towards developing model-based stabilizing controllers. The linearized EoM aids in developing high-fidelity experimental data-driven transfer function models. The coupled heave-yaw transfer function model is improved to an auto-regressive moving average with exogenous input (ARMAX) model structure. The acquired models facilitate the use of the multi-parameter root-locus (MPRL) technique to design baseline controllers for a cross-coupled multi-input, multi-output (MIMO) MicroROV. The controller gains are further optimized by employing an innovative Marine Predator Algorithm (MPA). The robustness of the designed controllers is gauged using gain and phase margins. In addition, the real-time controllers were deployed on an onboard embedded system utilizing Simulink′s automatic C++ code generation capabilities. Finally, pool tests of the MicroROV demonstrate the efficacy of the proposed control strategy.
Hydrodynamic Response Analysis of a Fixed Aquaculture Platform with a Horizontal Cylindrical Cage in Combined Waves and Currents
Authors: Shen Kanmin , Bi Chunwei , Jiang Zhenqiang , Guo Shouan , Wang Bin
Published: July 2023

Biofouling on net cages adversely affects structural safety and the growth of aquacultural fish. Therefore, a novel fixed aquaculture platform with a rotatable horizontal cylindrical cage is proposed in this study, which is convenient for the cleaning of biofouling. Based on ANSYS, the numerical model of the fixed aquaculture platform was established. The response results of the strain, acceleration, and displacement of the structure under the combined action of waves and currents at three typical attack angles were calculated. The effects of water depth and cage rotation on the hydrodynamic response of the structure are discussed. The results show that the strain, acceleration, and displacement of the cage increase with the increase in wave height; however, the change with the wave period is not obvious. The direction perpendicular to the long axis of the cage is the most unfavorable load direction. The acceleration of each position increases with the increase in water depth; however, the strain response has the opposite trend. When the rotation constraint of the horizontal cylindrical cage is released, the acceleration of the cage is larger than that when the cage is fixed. The rotation of the cage has a tiny effect on the structural strain and load acting on the structure.