bluuebunny/crossref_metadata_2025 huggingface dataset:
A Quantitative Comparison between Shannon and Tsallis–Havrda–Charvat Entropies Applied to Cancer Outcome Prediction
Authors: Brochet Thibaud , Lapuyade-Lahorgue Jérôme , Huat Alexandre , Thureau Sébastien , Pasquier David , Gardin Isabelle , Modzelewski Romain , Gibon David , Thariat Juliette , Grégoire Vincent , Vera Pierre , Ruan Su
Published: March 2022

In this paper, we propose to quantitatively compare loss functions based on parameterized Tsallis–Havrda–Charvat entropy and classical Shannon entropy for the training of a deep network in the case of small datasets which are usually encountered in medical applications. Shannon cross-entropy is widely used as a loss function for most neural networks applied to the segmentation, classification and detection of images. Shannon entropy is a particular case of Tsallis–Havrda–Charvat entropy. In this work, we compare these two entropies through a medical application for predicting recurrence in patients with head–neck and lung cancers after treatment. Based on both CT images and patient information, a multitask deep neural network is proposed to perform a recurrence prediction task using cross-entropy as a loss function and an image reconstruction task. Tsallis–Havrda–Charvat cross-entropy is a parameterized cross-entropy with the parameter α. Shannon entropy is a particular case of Tsallis–Havrda–Charvat entropy for α=1. The influence of this parameter on the final prediction results is studied. In this paper, the experiments are conducted on two datasets including in total 580 patients, of whom 434 suffered from head–neck cancers and 146 from lung cancers. The results show that Tsallis–Havrda–Charvat entropy can achieve better performance in terms of prediction accuracy with some values of α.
Sample Entropy as a Tool to Assess Lumbo-Pelvic Movements in a Clinical Test for Low-Back-Pain Patients
Authors: Thiry Paul , Nocent Olivier , Buisseret Fabien , Bertucci William , Thevenon André , Simoneau-Buessinger Emilie
Published: March 2022

Low back pain (LBP) obviously reduces the quality of life but is also the world’s leading cause of years lived with disability. Alterations in motor response and changes in movement patterns are expected in LBP patients when compared to healthy people. Such changes in dynamics may be assessed by the nonlinear analysis of kinematical time series recorded from one patient’s motion. Since sample entropy (SampEn) has emerged as a relevant index measuring the complexity of a given time series, we propose the development of a clinical test based on SampEn of a time series recorded by a wearable inertial measurement unit for repeated bending and returns (b and r) of the trunk. Twenty-three healthy participants were asked to perform, in random order, 50 repetitions of this movement by touching a stool and another 50 repetitions by touching a box on the floor. The angular amplitude of the b and r movement and the sample entropy of the three components of the angular velocity and acceleration were computed. We showed that the repetitive b and r “touch the stool” test could indeed be the basis of a clinical test for the evaluation of low-back-pain patients, with an optimal duration of 70 s, acceptable in daily clinical practice.
Relative Entropy of Correct Proximal Policy Optimization Algorithms with Modified Penalty Factor in Complex Environment
Authors: Chen Weimin , Wong Kelvin Kian Loong , Long Sifan , Sun Zhili
Published: March 2022

In the field of reinforcement learning, we propose a Correct Proximal Policy Optimization (CPPO) algorithm based on the modified penalty factor β and relative entropy in order to solve the robustness and stationarity of traditional algorithms. Firstly, In the process of reinforcement learning, this paper establishes a strategy evaluation mechanism through the policy distribution function. Secondly, the state space function is quantified by introducing entropy, whereby the approximation policy is used to approximate the real policy distribution, and the kernel function estimation and calculation of relative entropy is used to fit the reward function based on complex problem. Finally, through the comparative analysis on the classic test cases, we demonstrated that our proposed algorithm is effective, has a faster convergence speed and better performance than the traditional PPO algorithm, and the measure of the relative entropy can show the differences. In addition, it can more efficiently use the information of complex environment to learn policies. At the same time, not only can our paper explain the rationality of the policy distribution theory, the proposed framework can also balance between iteration steps, computational complexity and convergence speed, and we also introduced an effective measure of performance using the relative entropy concept.
Analysis of Fault Characteristics of Distribution Network with PST Loop Closing Device under Small Current Grounding System
Authors: Xu Zhi , Tang Jianxiong , Jiang Yupeng , Qin Risheng , Ma Hongsheng , Yang Yongchun , Zhao Chengyong
Published: March 2022

With the rapid development of cities and the increasing complexity of distribution network systems, the cableization of transmission lines and the diversification of power users have brought new challenges to the supply reliability of distribution networks. Short-time outages caused by power outages and maintenance are one of the factors that affect the reliability of the power supply in the distribution network. The non-stop load transfer through a phase-shifting transformer (PST) operation can effectively improve the reliability of power supply to complex distribution systems. Considering the operation mode and structure form and fault type of the urban distribution network in China, comparing and analyzing the applicable scenarios of different neutral grounding methods, and based on the structure and zero sequence path characteristics of PST, an improved PST-based phase shifting and grounding transformer loop closing device with low power consumption is proposed. The fault characteristics of the PST-based loop closing device under the small current grounding system are also analyzed by the sequence component method, and, finally, the effectiveness of the phase-shifting and grounding transformer device is verified by simulation under PSCAD/EMTDC for fault routing and protection configuration of the urban distribution network in China.
Pre-Normative Charging Technology Roadmap for Heavy-Duty Electric Vehicles in Europe
Authors: Farzam Far Mehrnaz , Pihlatie Mikko , Paakkinen Marko , Antila Marko , Abdulah Aida
Published: March 2022

This paper presents a pre-normative roadmap that foresees the developments in the charging of heavy-duty electric vehicles (HD-EVs). It supports and facilitates the future standardization efforts of charging technologies by creating an overview of the popularity of charging technologies and the end users’ needs. The required input for the work was collected using a comprehensive investigation on the available charging technologies and their standardization, reviewing the existing roadmaps and research work, and conducting surveys and interviews of end users and technical stakeholders. According to the findings, a pantograph on the roof of a vehicle and plug-based charging are currently the most used charging interfaces. This trend is likely to continue in the future, since (1) pantographs on vehicle roofs, (2) pantographs on infrastructure, and (3) plugs were graded as charging interfaces with the highest potential by the participants of the technical survey. Static and conductive charging technologies show more potential than dynamic and wireless charging technologies. Nevertheless, inductive charging may be a future charging solution for HD-EVs if the current bottlenecks in the technology can be addressed. These bottlenecks include high prices, slightly lower efficiency, lack of standardization, the maximum achievable power, and safety concerns. Furthermore, interoperability was repeatedly mentioned as the main challenge for today’s charging technologies.
Analyzing Intersectoral Benefits of District Heating in an Integrated Generation and Transmission Expansion Planning Model
Authors: Schwaeppe Henrik , Böttcher Luis , Schumann Klemens , Hein Lukas , Hälsig Philipp , Thams Simon , Baquero Lozano Paula , Moser Albert
Published: March 2022

In the field of sector integration, the expansion of district heating (DH) is traditionally discussed with regard to the efficient integration of renewable energy sources (RES) and excess heat. But does DH exclusively benefit from other sectors or does it offer advantages in return? So far, studies have investigated DH only as a closed system or determined intersectoral benefits in a highly aggregated approach. We use and expand an integrated generation and transmission expansion planning model to analyze how the flexibility of DH benefits the energy system and the power transmission grid in particular. First of all, the results confirm former investigations that show DH can be used for efficient RES integration. Total annual system cost can be decreased by expanding DH, due to low investment cost and added flexibility, especially from large-scale heat storage. The high short-term efficiency of heat storage—in combination with electric heating technologies—can be exploited to shift heat demand temporally and, using multiple distributed units, locally to solve electric grid congestion. Although it is unclear whether these results can be replicated in the real world, due to the aggregation and detail of the model, further research in this direction is justified.
Accurate Calculation of Iron Loss of High-Temperature and High-Speed Permanent Magnet Synchronous Generator under the Conditions of SVPWM Modulation
Authors: Zhuo Liang , Yang Du , Sun Ruolan , Sun Lu , Zou Jibin
Published: March 2022

The high-temperature and high-speed permanent magnet synchronous generator (HTHSPMSG) is the core component ensuring the efficient and safe operation of the high-speed aircraft power supply system. At present, the existing iron loss model fails to meet the requirements for the precise calculation of the iron loss of HTHSPMSG under high-temperature and high-frequency conditions. In this paper, a 40 kW, 18,000 rpm HTHSPMSG is used to study the accurate calculation of iron loss at an ambient temperature of 350 °C. Considering the influence of high temperature and high frequency on the loss and performance of electromagnetic materials, a test platform for the loss performance of the magnetic core materials is established. Then, according to the loss performance of the electromagnetic material, the corresponding iron loss coefficient is fitted by the variable coefficient iron loss separation model. In addition, the digital twin field-circuit co-simulation method is proposed to guarantee the accuracy of the iron loss calculation. Then, the influence of carrier frequencies and modulation ratios on the iron loss characteristics of the HTHSPMSG under the conditions of SVPWM modulation is studied. Lastly, the effectiveness of the proposed method is verified by the experimental results, which provide a reference for the accurate analysis of iron loss of the same type of HTHSPMSG.
Tools for Network Smart City Management—The Case Study of Potential Possibility of Managing Energy and Associated Emissions in Metropolitan Areas
Authors: Makieła Zbigniew J. , Kinelski Grzegorz , Stęchły Jakub , Raczek Mariusz , Wrana Krzysztof , Michałek Janusz
Published: March 2022

The article uses the case study of a polycentric metropolitan area as a starting point for a debate about the available tools for managing the network aspects of intelligent cities. We show that the construction of talents, the development of knowledge among officials and inhabitants, and technological tools such as Hubgrade (which allows for heat delivery process control, supervision, inspection, and results in emission reduction) are prerequisites for the sustainable development of cities. It is critical to understand that technological solutions are insufficient to accomplish such a task. Relevant stakeholders need to consciously take advantage of technological tools and build and utilise 4T potential and the self-learning capabilities of the organisations. An inherent feature of an organisation, such as a city, is cooperation between the people who build it. The main challenges of cities includes the reduction of pollutants resulting from the use of transport, heat sources, or energy production. In many cities, an efficient manner of reducing carbon dioxide emissions is to limit the consumption of thermal energy. In order to simultaneously maintain thermal comfort, in this situation, it is necessary to use intelligent technologies. The paper includes research related to the knowledge and development of 4T potentials (technology, trust, talent, tolerance) and to networking expansion by introducing the automated Hubgrade system, used in Warsaw district heating, into a similar metropolitan area. Along with an increase in the significance of relations, information, and knowledge as a key organisational resource, cities, as organisations, have become an important element of contemporary communities and organisations. They have the possibility of a positive climate change. The possibility of cooperation and networking between people forming an organisation is its inherent feature, such as in the Hubgrade project. Conclusions and recommendations are drawn for the analysed case—linking 4T potentials and the Hubgrade system—with the potential for future generalisations and extrapolations. The authors performed a simulation of possible energy savings and the reduction of harmful emissions in Metropolis GZM.
Habitat Suitability Modeling of Rare Turkeybeard (Xerophyllum asphodeloides) Species in the Talladega National Forest, Alabama, USA
Authors: Bektas Volkan , Bettinger Pete , Nibbelink Nate , Siry Jacek , Merry Krista , Henn Katrina Ariel , Stober Jonathan
Published: March 2022

This study focused on the rare and threatened plant species eastern turkeybeard (Xerophyllum asphodeloides (L.) Nutt.) and its presence or absence in the Talladega National Forest in Alabama, USA. An ensemble suitable habitat map was developed using four different modeling methods (MaxEnt, Generalized Linear Model, Generalized Additive Model, and Random Forest). AUC evaluation scores for each model were 0.99, 0.96, 0.98, and 0.99, respectively. Biserial correlation scores for models ranged from 0.71 (GLM) to 0.94 (RF). The four different models agreed suitable habitat was found to cover 159.57 ha of the land. The ground slope variable was the most contributive variable in the MaxEnt and RF models and was also significant in the GLM and GAM models. The knowledge gained from this research can be used to establish and implement habitat suitability strategies across the Talladega National Forest and similar ecosystems in the southern United States.
Tree-Ring Stable Carbon Isotope as a Proxy for Hydroclimate Variations in Semi-Arid Regions of North-Central China
Authors: Kang Shuyuan , Loader Neil J. , Wang Jianglin , Qin Chun , Liu Jingjing , Song Miao
Published: March 2022

Carbon and oxygen isotope ratios (δ13C and δ18O) were measured in annual tree-ring cellulose samples dated from 1756 to 2015 CE. These samples were extracted from Chinese pine (Pinus tabulaeformis Carr.) trees located in a semi-arid region of north-central China. We found that tree-ring δ13C and δ18O values both recorded similar climatic signals (e.g., temperature and moisture changes), but found that tree-ring δ13C exhibited a stronger relationship with mean temperature, precipitation, average relative humidity, self-calibrating Palmer drought severity index (scPDSI), and standard precipitation evaporation index (SPEI) than δ18O during the period 1951–2015 CE. The strongest correlation observed was between tree-ring δ13C and scPDSI (previous June to current May), which explains ~43% of the variance. The resulting 130-year reconstruction reveals severe drought events in the 1920s and a sustained drying trend since the 1980s. This hydroclimate record based on tree-ring δ13C data also reveals similar dry and wet events to other proxy data (i.e., tree-ring width and historical documentation) that have allowed reconstructions to be made across the northern fringe of the Asian summer monsoon region. Our results suggest that both large-scale modes of climate variability (e.g., El Niño-Southern Oscillation, Pacific Decadal Oscillation, and North Atlantic Oscillation) and external forcing (e.g., solar variability) may have modulated moisture variability in this region. Our results imply that the relationship between tree-ring δ18O and local climate is less well-characterized when compared to δ13C and may be affected more strongly by the influences of these different atmospheric circulation patterns. In this semi-arid region, tree-ring δ13C appears to represent a better tool with which to investigate historical moisture changes (scPDSI).
Effect of Climate Change on the Growth of Tree Species: Dendroclimatological Analysis
Authors: Gauli Archana , Neupane Prem Raj , Mundhenk Philip , Köhl Michael
Published: March 2022

Tree ring analyses can assist in revealing the effect of gradual change in climatic variables on tree growth. Dendroclimatic analyses are of particular importance in evaluating the climate variables that affect growth significantly and in determining the relative strength of different climatic factors. In this study, we investigated the growth performance of Pinus sylvestris, Picea abies, and Pseudotsuga menziesii in northern Germany using standard dendrochronological methods. The study further analyzed tree growth responses to different climatic variables over a period of a hundred years. Both response function analysis and moving correlation analysis confirmed that the climate and growth relationship is species-specific and variable and inconsistent over time. Scots pine and Douglas fir growth were stimulated mainly by the increase in winter temperatures, particularly the January, February, and March temperatures of the current year. In contrast, Norway spruce growth was stimulated mainly by the increase in precipitation in May, June, and July and the increase in temperature in March of the current year. Climate projections for central Europe foresee an increase in temperature and a decrease in the amount of summer precipitation. In a future, warmer climate with drier summers, the growth of Norway spruce might be negatively affected.
Predicting Dog Emotions Based on Posture Analysis Using DeepLabCut
Authors: Ferres Kim , Schloesser Timo , Gloor Peter A.
Published: March 2022

This paper describes an emotion recognition system for dogs automatically identifying the emotions anger, fear, happiness, and relaxation. It is based on a previously trained machine learning model, which uses automatic pose estimation to differentiate emotional states of canines. Towards that goal, we have compiled a picture library with full body dog pictures featuring 400 images with 100 samples each for the states “Anger”, “Fear”, “Happiness” and “Relaxation”. A new dog keypoint detection model was built using the framework DeepLabCut for animal keypoint detector training. The newly trained detector learned from a total of 13,809 annotated dog images and possesses the capability to estimate the coordinates of 24 different dog body part keypoints. Our application is able to determine a dog’s emotional state visually with an accuracy between 60% and 70%, exceeding human capability to recognize dog emotions.
Value of Acute Kidney Injury in Predicting Mortality in Vietnamese Patients with Decompensated Cirrhosis
Authors: Nguyen Nghia N. , Mai Tan H. N. , Vo Nghia H. , Vo Cuong T. , Ngo Nhi T. Y. , Vi Mai T. , Nguyen Thang
Published: March 2022

Background: Acute kidney injury remains a common complication with a poor prognosis, and is a significant predictor of mortality in cirrhosis patients. We aimed to determine the percentage of acute kidney injury in decompensated cirrhosis patients and evaluate the treatment results of acute kidney injury as well as several factors related to the mortality of decompensated cirrhosis patients. Methods: A prospective study was conducted on decompensated cirrhosis patients in Can Tho City, Vietnam, from 2019 to 2020. Decompensated cirrhosis patients were found to have acute kidney injury on admission by a blood creatinine test. They were treated according to ICA 2015 standards, after which they were monitored and evaluated for treatment outcomes during hospitalization. Results: Of 250 decompensated cirrhosis patients, 64 (25.6%) had acute kidney injury and 37.5% died. Several factors were associated with mortality in decompensated cirrhosis patients, such as Child–Pugh C (p = 0.02; OR = 3, 95% CI 1.5–6.3), acute kidney injury (p < 0.0001; OR = 9.5, 95% CI 4.3–21.1), hyponatremia (p = 0.01; OR = 2.5, 95% CI 1.2–5.1), elevated total bilirubin > 51 µmol/L (p = 0.03; OR = 2.2, 95% CI 1.1–4.6), and prothrombin < 70% (p = 0.03; OR = 6.8, 95% CI 1–51.6). Hypoalbuminemia was unrelated to mortality in these patients (p = 0.8; OR = 1.2, 95% CI 0.5–2.7), but gastrointestinal bleeding significantly increased mortality in these patients up to 2.3 times (p = 0.03; OR = 2.3, 95% CI 1.1–4.9). Three independent factors regarding mortality in decompensated cirrhosis patients included acute kidney injury, hepatic encephalopathy, and gastrointestinal bleeding. The rate of acute kidney injury in patients with decompensated cirrhosis was 25.6%; the mortality rate was 37.5%. Conclusions: Acute kidney injury was a valuable predictor of mortality in Vietnamese patients with decompensated cirrhosis.
Clinical Characteristics in the Longitudinal Follow-Up of APECED Syndrome in Southern Croatia—Case Series
Authors: Skrabic Veselin , Skrabic Ivna , Skrabic Roko , Roje Blanka , Simunovic Marko
Published: March 2022

Background: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a rare monogenetic autosomal recessive disorder caused by a mutation in the autoimmune regulator (AIRE) gene characterized by complex phenotypic characteristics discovered over years of follow-up. Methods: 7 patients were recruited in this case series in a period of the last 37 years from Southern Croatia. All patients were screened for AIRE R257X mutations. Results: This study group had a mean current age of 25.3 years (age range from 5.4 to 40.2 years), while the mean age at the onset of the disease was 6.5 years (age range from 0.7 to 9.2 years) and with a mean follow-up period of 17.8 years. The overall prevalence of APECED syndrome is estimated to be 1 in 75,000. The most common initial manifestation of the disease was onychodystrophy, while the first major component of APECED syndrome was chronic mucocutaneous candidiasis. Conclusions: APECED is a ‘‘multi-faced’’ disease based on the very unpredictable and inconsistent onset of major components. Furthermore, based on our results, we suggest that onychodystrophy could be included as a warning sign of APECED syndrome.
Variable Clinical Appearance of the Kir2.1 Rare Variants in Russian Patients with Long QT Syndrome
Authors: Zaklyazminskaya Elena , Polyak Margarita , Shestak Anna , Sadekova Mariam , Komoliatova Vera , Kiseleva Irina , Makarov Leonid , Podolyak Dmitriy , Glukhov Grigory , Zhang Han , Abramochkin Denis , Sokolova Olga S.
Published: March 2022

Background: The KCNJ2 gene encodes inward rectifier Kir2.1 channels, maintaining resting potential and cell excitability. Presumably, clinical phenotypes of mutation carriers correlate with ion permeability defects. Loss-of-function mutations lead to QTc prolongation with variable dysmorphic features, whereas gain-of-function mutations cause short QT syndrome and/or atrial fibrillation. Methods: We screened 210 probands with Long QT syndrome for mutations in the KCNJ2 gene. The electrophysiological study was performed for the p.Val93Ile variant in the transfected CHO-K1 cells. Results: We found three rare genetic variants, p.Arg67Trp, p.Val93Ile, and p.R218Q, in three unrelated LQTS probands. Probands with p.Arg67Trp and p.R218Q had a phenotype typical for Andersen-Tawil (ATS), and the p.Val93Ile carrier had lone QTc prolongation. Variant p.Val93Ile was initially described as a gain-of-function pathogenic mutation causing familial atrial fibrillation. We validated electrophysiological features of this variant in CHO-K1 cells, but no family members of these patients had atrial fibrillation. Using ACMG (2015) criteria, we re-assessed this variant as a variant of unknown significance (class III). Conclusions: LQT7 is a rare form of LQTS in Russia, and accounts for 1% of the LQTS cohort. Variant p.Val93Ile leads to a gain-of-function effect in the different cell lines, but its clinical appearance is not so consistent. The clinical significance of this variant might be overestimated.
Identification of the Complete Chloroplast Genome of Malus zhaojiaoensis Jiang and Its Comparison and Evolutionary Analysis with Other Malus Species
Authors: Wang Xun , Wang Daru , Gao Ning , Han Yuepeng , Wang Xiaofei , Shen Xiang , You Chunxiang
Published: March 2022

The genus Malus is rich in species and many of its plastid genomes have been released. However, limited resources and few markers are not conducive to the comparison of differences among species and resource identification and evaluation. In this study, the complete chloroplast genome of Malus zhaojiaoensis was studied by NGS sequencing, with a total length of 159998 bp. It consists of four regions, LSC (88,070 bp), IRB (26,359 bp), SSC (19,210 bp) and IRA (26,359 bp). M. zhaojiaoensis cp genome contained a total of 111 genes made up of three classes: 78 coding sequences, 29 tRNA genes, and four rRNA genes. In addition, a total of 91 SSRs and 43 INEs were found in the M. zhaojiaoensis cp genome, which was slightly different from M. baccata and M. hupehensis in number. The analysis of codon usage and RNA editing showed that high-frequency codons tended to end at A/U bases and RNA editing mainly occurred at the second codon. Comparative genome analysis suggested that the cp genomes of eight Malus species had higher overall similarity, but there were more variation hotspots (rps16_trnK-UUU, trnG-UCC_atpA, atpH_atpF, trnT-GGU_psbD, etc.) in the LSC region. By building evolutionary trees, it can be clearly observed that M. zhaojiaoensis formed a large group with eight species of Malus, but was relatively independent in differentiation. In conclusion, this study provides high-quality chloroplast genome resources of M. zhaojiaoensis and discusses the genetic variation characteristics of Malus genus. The findings of this study will provide a good reference for plastid genome assembly and interspecific comparison in the future.
Spiritual Care: A Description of Family Members’ Preferences of Spiritual Care Nursing Practices in Intensive Care Units in a Private Hospital in Kwa-Zulu Natal, South Africa
Authors: Zambezi Mercy , Emmamally Waheedha , Mooi Nomaxabiso
Published: March 2022

Background: Spiritual care is a part of the holistic care that enables family members in intensive care units to find meaning in their life events and simultaneously bolsters their resilience and coping tools. Objective: To determine family members’ preferences of spiritual care practices that they require from nurses working in intensive care units. Methods: A quantitative, descriptive, cross-sectional study was conducted in the intensive care units of a private hospital in the province of KwaZulu-Natal. Data, using the Nurse Spiritual Therapeutic Scale, were collected from a purposive sample of family members (n = 47). Data were analyzed using descriptive statistics. Results: The mean overall Nurse Spiritual Therapeutic Scale was 58.4 (20–80). The most preferred and least preferred spiritual care practices by family members were “to be helped to have quiet time and space”, (M = 3.32, SD = 0.59) and “to arrange for a chaplain to visit them” (M = 2.70, SD= 0.91), respectively. Conclusion: The mean overall NSTS score indicated that there was a strong preference among family members for nurses to provide them with spiritual care in the intensive care units. However, due to the diversity of family members’ preferences it remains important that family members guide intensive care nurses in their spiritual care.
Influence of Climate Change on Metabolism and Biological Characteristics in Perennial Woody Fruit Crops in the Mediterranean Environment
Authors: Medda Silvia , Fadda Angela , Mulas Maurizio
Published: March 2022

The changes in the state of the climate have a high impact on perennial fruit crops thus threatening food availability. Indeed, climatic factors affect several plant aspects, such as phenological stages, physiological processes, disease-pest frequency, yield, and qualitative composition of the plant tissues and derived products. To mitigate the effects of climatic parameters variability, plants implement several strategies of defense, by changing phenological trends, altering physiology, increasing carbon sequestration, and metabolites synthesis. This review was divided into two sections. The first provides data on climate change in the last years and a general consideration on their impact, mitigation, and resilience in the production of food crops. The second section reviews the consequences of climate change on the industry of two woody fruit crops models (evergreen and deciduous trees). The research focused on, citrus, olive, and loquat as evergreen trees examples; while grape, apple, pear, cherry, apricot, almond, peach, kiwi, fig, and persimmon as deciduous species. Perennial fruit crops originated by a complex of decisions valuable in a long period and involving economic and technical problems that farmers may quickly change in the case of annual crops. However, the low flexibility of woody crops is balanced by resilience in the long-life cycle.
Characterization of Young Shoot Population, Yield, and Nitrogen Demands of Tea (Camellia sinensis L.) Harvested under Different Standards
Authors: Long Lizhi , Shi Yuanzhi , Ma Lifeng , Ruan Jianyun
Published: March 2022

The quality of green tea is greatly influenced by the harvest standards for young shoots. The present field experiment was conducted to characterize the young shoot populations, yields, and nitrogen (N) demands of tea plants subjected to four different harvest standards, i.e., buds with one, two, or three young expanding leaves (referred to as B1L, B2L, and B3L, respectively) and a combination of B1L and B3L (B1L/B3L) throughout the year. Weight per shoot was closely related to the number of expanding leaves and was greater in B3L than B1L and B2L, and also greater in summer and autumn than in spring, whereas B1L revealed the greatest young shoot density and highest N concentration. Annual shoot yield and shoot N content were largest in B3L and decreased in the following order: B3L > B2L ≈ B1L/B3L > B1L. However, in the early spring the shoot density, yield, and shoot N content of B1L were much higher than those of B3L. The harvest of B3L significantly reduced the biomass of brown roots and its ratio against the above-ground biomass compared to other harvest standards, suggesting a decreased allocation of carbon to the root system due to seasonal removal. The N dilution curve (Nys = a × Yysb, where Nys is the shoot N content and Yys is the shoot yield) of spring tea differed markedly from those of summer and autumn teas, suggesting different coordination properties for shoot growth and N supply among the seasons. The annual harvest index (NHI) measured by 15N traces ranged between 0.18 and 0.23, indicating relatively low N allocation to young shoots, whereby large proportions (58.2–66.9% of the total 15N absorption) remained in the plant at the end of the experiment. In conclusion, the seasonal distribution of the shoot density, weight per shoot, yield, and N demands vary with harvest standards and highlight the importance of N precision management in tea production to be finely tuned to meet the changes in harvest season and requirements.
Mobile Health (m-Health) in Retrospect: The Known Unknowns
Authors: Istepanian Robert S. H.
Published: March 2022

For nearly two decades, mobile health or (m-Health) was hailed as the most innovative and enabling area for the digital transformation of healthcare globally. However, this profound vision became a fleeting view since the inception and domination of smart phones, and the reorientation of the concept towards the exclusivity of global smart phone application markets and services. The global consumerization of m-Health in numerous disciplines of healthcare, fitness and wellness areas is unprecedented. However, this divergence between ‘mobile health capitalism’ and the ‘science of mobile health’ led to the creation of the ‘m-Health schism’. This schism was sustained by the continued domination of the former on the expense of the latter. This also led to increased global m-Health inequality and divide between the much-perceived health and patient benefits and the markets of m-Health. This divergence was more evident in low and middle income (LMIC) countries compared to the developed world. This powerful yet misguided evolution of the m-Health was driven essentially by complex factors. These are presented in this paper as the ‘known unknowns’ or ‘the obvious but sanctioned facts’ of m-Health. These issues had surreptitiously contributed to this reorientation and the widening schism of m-Health. The collateral damage of this process was the increased shift towards understanding ‘digital health’ as a conjecture term associated with mobile health. However, to date, no clear or scientific views are discussed or analyzed on the actual differences and correlation aspects between digital and mobile health. This particular ‘known unknown’ is presented in detail in order to provide a rapprochement framework of this correlation and valid presentations between the two areas. The framework correlates digital health with the other standard ICT for the healthcare domains of telemedicine, telehealth and e-health. These are also increasingly used in conjunction with digital health, without clear distinctions between these terms and digital health. These critical issues have become timelier and more important to discuss and present, particularly after the world has been caught off guard by the COVID-19 pandemic. The much hyped and the profiteering digital health solutions developed in response of this pandemic provided a modest impact, and the benefits were mostly inadequate in mitigating the massive health, human, and economic impact of this pandemic. This largely commercial reorientation of mobile health was unable not only to predict the severity of the pandemic, but also unable to provide adequate digital tools or effective pre-emptive digital epidemiological shielding and guarding mechanisms against this devastating pandemic. There are many lessons to be learnt from the COVID-19 pandemic from the mobile and digital health perspectives, and lessons must be learnt from the past and to address the critical aspects discussed in this paper for better understanding of mobile health and effective tackling of future global healthcare challenges.
Pre- and Postnatal Fine Particulate Matter Exposure and Childhood Cognitive and Adaptive Function
Authors: McGuinn Laura A. , Wiggins Lisa D. , Volk Heather E. , Di Qian , Moody Eric J. , Kasten Eric , Schwartz Joel , Wright Robert O. , Schieve Laura A. , Windham Gayle C. , Daniels Julie L.
Published: March 2022

Increasing evidence exists for an association between early life fine particulate matter (PM2.5) exposure and several neurodevelopmental outcomes, including autism spectrum disorder (ASD); however, the association between PM2.5 and adaptive and cognitive function remains poorly understood. Participants included 658 children with ASD, 771 with a non-ASD developmental disorder, and 849 population controls from the Study to Explore Early Development. Adaptive functioning was assessed in ASD cases using the Vineland Adaptive Behavior Scales (VABS); cognitive functioning was assessed in all groups using the Mullen Scales of Early Learning (MSEL). A satellite-based model was used to assign PM2.5 exposure averages during pregnancy, each trimester, and the first year of life. Linear regression was used to estimate beta coefficients and 95% confidence intervals, adjusting for maternal age, education, prenatal tobacco use, race-ethnicity, study site, and season of birth. PM2.5 exposure was associated with poorer VABS scores for several domains, including daily living skills and socialization. Associations were present between prenatal PM2.5 and lower MSEL scores for all groups combined; results were most prominent for population controls in stratified analyses. These data suggest that early life PM2.5 exposure is associated with specific aspects of cognitive and adaptive functioning in children with and without ASD.
Validation of the Therapeutic Self-Care Scale-European Portuguese Version in Primary Care Type 2 Diabetes Adults
Authors: Cardoso Ana Filipa , Queirós Paulo , Amaral António Salgueiro , Fontes-Ribeiro Carlos , Rosa Amorim , Cruz Rui , Neto Matilde Agostinho , Felizardo Helena , Sidani Souraya
Published: March 2022

Self-care is an important nursing-sensitive outcome. Reliable and valid measures are needed for therapeutic self-care assessment that may inform the development and evaluation of individualized nursing interventions co-created with type 2 diabetes mellitus (T2DM) adults. The therapeutic self-care scale European Portuguese version (TSCS-EPV) is a validated generic measure that may be used to assess self-care in T2DM adults. Aim: To examine the psychometric properties of the TSCS-EP version in T2DM adults, in primary health care. Methods: A cross-sectional pilot study in a convenience sample of 80 adults with T2DM from two primary health care centers in Portugal was conducted. Individuals completed the Portuguese version of the TSC scale. Results: A three-factor solution emerged from the principal component analysis: “Recognizing and managing signs and symptoms”; “Managing changes in health condition” and “Managing medication”, explaining 75% of the total variance. Total scale Cronbach’s alpha was 0.884 and for the three factors ranged from 0.808 to 0.954. Conclusion: the therapeutic self-care scale European Portuguese version is a promising scale for assessing therapeutic self-care abilities in adults with T2DM in primary care settings. More consistent results on its validity and reliability are needed for it to be used in the country.
Adjusting the Canadian Healthcare System to Meet Newcomer Needs
Authors: Lane Ginny , Vatanparast Hassan
Published: March 2022

Newcomers’ ability to access healthcare can be impacted by cultural, religious, linguistic, and health status differences. A variety of options are available to support the development of healthcare systems to equitably accommodate newcomers, including the use of basic English and other languages in public health information, engagement with immigrant communities to advise on program development, offering culturally competent health services, interpretation services, and through creating space to collaborate with traditional practitioners. This study employed in-depth interviews with newcomer families from the Healthy Immigrant Children Study that had been living in Regina or Saskatoon, Saskatchewan, Canada, for less than 5 years, as well as with healthcare providers and immigrant service providers to understand how to improve healthcare services. Analysis of participant quotes related to accessible healthcare services revealed five main themes: (1) responsive, accessible services, (2) increasing cultural competence, (3) targeted newcomer health services, (4) increasing awareness of health services, and (5) newcomer engagement in planning and partnerships. An accessible healthcare system should include primary healthcare sites developed in partnership with newcomer service organizations that offer comprehensive care in a conveniently accessible and culturally responsive manner, with embedded interpretation services. The Saskatchewan healthcare system needs to reflect on its capacity to meet newcomer healthcare needs and strategically respond to the healthcare needs of an increasingly diverse population.
Management Decisions: The Effectiveness and Size of the Emergency Medical Team
Authors: Robakowska Marlena , Ślęzak Daniel , Żuratyński Przemysław , Krzyżanowski Kamil , Tyrańska-Fobke Anna , Błażek Magdalena , Woroń Jarosław
Published: March 2022

In Poland, often for economic reasons, the staffing of medical rescue teams is limited to the legally required minimum. This gives rise to problems related to the effectiveness and efficiency of medical rescue teams. A literature review did not find any sources addressing the issue of the verification of the effectiveness of paramedic teams depending on the personnel composition of units. The aim of the study was to analyze the effectiveness of resuscitation depending on the size of the medical rescue team, comparing the work of two- and three-person teams. In total, 100 two-person teams and an analogous number of three-person units were studied. Statistical analyses were performed using the IBM SPSS Statistics 24 package. The results showed that the assessment of the condition of the victim as well as the ability to assess the heart rhythm and monitor the condition during advanced measures were more effective in three-person teams; three-person teams also used oxygen more frequently during advanced life support (ALS). Most of the elements influenced the quality of resuscitation and it can be unequivocally stated that the work of three rescuers is more efficient and definitely more effective.
Evaluation of Tourism Development Efficiency and Spatial Spillover Effect Based on EBM Model: The Case of Hainan Island, China
Authors: Zhang Pengfei , Yu Hu , Shen Mingzhe , Guo Wei
Published: March 2022

Tourism development efficiency is one of the key scales to measure the development quality of tourism destination. This study improves the existing input–output index system of tourism efficiency evaluation; knowledge innovation is introduced into the input index, and environmental health pressure is introduced into the output index. Based on the case of Hainan Island, we used the EBM model compatible with radial and non-radial data to evaluate the tourism development efficiency. In order to make up the deficiency of spatial effect analysis based on the geographical distance weight matrix, the spatial spillover effect of tourism development in Hainan Island was analyzed based on a geographical distance weight matrix and an economic distance weight matrix. The findings indicate that nearly 20 years of the Hainan tourism development efficiency mean value was 0.7435, represented by Sanya, and Haikou city of Hainan’s tourism industry development level was higher. However, the spatial spillover effect of Hainan’s overall tourism development is not good. In addition to Tunchang, Ledong city suggests that an appropriate increase in tourism elements, such as investment, expands the scale of the tourism industry, and most cities follow the law of diminishing marginal utility and inappropriate scale blindly. Especially in the face of knowledge innovation becoming the main factor hindering the efficiency of tourism development, we should pay more attention to technological innovation and management reform and coordinate the relationship between tourism development and ecological environment protection.
Violent Behaviours among Adolescents and Young Adults: Association with Psychoactive Substance Use and Parenting Styles
Authors: Benedetti Elisa , Colasante Emanuela , Cerrai Sonia , Gerra Gilberto , Tadonio Leonardo , Pellegrini Pietro , Molinaro Sabrina
Published: March 2022

This study extends existing research on the relationship between psychoactive substance use among young people and violent behaviour, by evaluating the possible effect of the modification of parenting in a nationally representative sample of 14,685 Italian students drawn from the 2019 wave of the ESPAD Italia survey (51% male; mean age about 17 years). Parental dimensions considered in the study were rule-setting, monitoring, and emotional support, as well as the possible absence of a parent. Relative risk ratios and binary logistic regressions were used to estimate the associations separately for adolescents (15–17) and young adults (18–19). Overall, parental rule-setting, perceived parental monitoring, and emotional support were protective factors for substance use, and the strength of this relationship increased with the frequency of use. Among adolescents, the absence of a parent represented a risk factor. In both age groups, the odds of engaging in violent behaviour was increased among those reporting alcohol intoxication and substance use and the greater the frequency of use, the greater the increase in the odds. As parental monitoring and emotional support decreased, the odds of engaging in violent behaviour increased (except in the case of lower parental support among young adults), while the opposite applies to parental rule-setting. The odds of engaging in violent behaviour were increased among those reporting the absence of a parent only in the adolescent age group. Parental rule-setting was found to have an effect only among adolescents, increasing the odds of violent behaviour among frequent drinkers. Our results might be helpful to signal adolescents who would be more prone to adopt violent behaviour in order to target prevention policies.
The #StopAsianHate Movement on Twitter: A Qualitative Descriptive Study
Authors: Cao Jiepin , Lee Chiyoung , Sun Wenyang , De Gagne Jennie C.
Published: March 2022

Evidence-based intervention and policy strategies to address the recent surge of race-motivated hate crimes and other forms of racism against Asian Americans are essential; however, such efforts have been impeded by a lack of empirical knowledge, e.g., about racism, specifically aimed at the Asian American population. Our qualitative descriptive study sought to fill this gap by using a data-mining approach to examine the contents of tweets having the hashtag #StopAsianHate. We collected tweets during a two-week time frame starting on 20 May 2021, when President Joe Biden signed the COVID-19 Hate Crimes Act. Screening of the 31,665 tweets collected revealed that a total of 904 tweets were eligible for thematic analysis. Our analysis revealed five themes: “Asian hate is not new”, “Address the harm of racism”, “Get involved in #StopAsianHate”, “Appreciate the Asian American and Pacific Islander (AAPI) community’s culture, history, and contributions” and “Increase the visibility of the AAPI community.” Lessons learned from our findings can serve as a foundation for evidence-based strategies to address racism against Asian Americans both locally and globally.