bluuebunny/crossref_metadata_2025 huggingface dataset:
Seroprevalence of Maedi-Visna Infection in Sheep in the Central Black Sea Region of Türkiye
Authors: Kuruçay Hanne Nur , Müftüoğlu Bahadir , Gözel Seda , Elhag Ahmed Eısa , Tamer Cüneyt , Gümüşova Semra , Albayrak Harun
Published: July 2024

Maedi-Visna is a slowly progressive infection of sheep that affects the respiratory and nervous systems and causes significant yield losses worldwide. This study was conducted to assess the seroprevalence of Maedi-Visna infection in sheep across several provinces in the Central Black Sea region of Türkiye, namely Samsun, Sinop, Ordu, Giresun, Amasya and Tokat. A total of 476 sheep serum samples were collected for further analysis. The presence of antibodies in the sera was determined by Ab ELISA. As a result of the study, 263 (55.25%) blood serum samples were positive for the presence of MVV antibodies. Seropositivity rates by province were as follows: Samsun 45%, Sinop 80%, Ordu 58.75%, Giresun 35%, Amasya 38.75%, Tokat 75%. Notably, our findings suggest a significantly high seroprevalence of Maedi-Visna infection in this region compared to other studies conducted in different parts of Türkiye This information is pivotal for understanding the extent of the infection in the sheep population of the Central Black Sea region and can contribute to the development of strategies for disease management and control.
Preduvjeti uspješnog ostvarenja nastave na
orguljama
Authors: Ljubenko Božidar
Published: July 2024

Postoje različiti pristupi, postupci i razmišljanja oko pitanja orguljske nastave te o tome koji su preduvjeti potrebni za kvalitetu njezinog uspješnog ostvarenja. Shodno tome „nameće“ se pitanje Kad je podobno vrijeme za početi s nastavom ovog instrumenta? U ovom radu literarno-empirijskim istraživanjem kroz analizu i tumačenje različitih pristupa i praksi nastavnika pokušat će se doprinijeti razjašnjavanju te problematike. Ovim istraživanjem iskazat će se mišljenja nastavnika koji predaju orgulje u glazbenim školama republike Hrvatske te kako o određenoj temi i problematici pišu glazbeni pedagozi u znanstvenim publikacijama. Na temelju istražene literature i provedenog empirijskog istraživanja možemo zaključiti kako je prethodno klavirsko znanje potrebno da bi se orguljske tehnike i vještine mogle lakše i uspješnije usvajati te je shodno tome srednjoškolsko vrijeme najproduktivnije za učenje orgulja. Doduše, u povijesti postoje slučajevi kada su talent/nadarenost, okolnosti i ustrajnost rezultirali uspješnošću. No, i dalje je neosporno kako klavirsko (pred)znanje pospješuje uspješnost, a time i kvalitetu nastave na orguljama. Nadalje, klavirsko znanje koje će učenik „donijeti/unijeti“ u srednjoškolsku nastavu orgulja pomoći će u uspješnijoj izgradnji njegovih znanja i umijeća potrebnih za ovladavanje tim kompleksnim instrumentom.
Probir kao prevencija slabog vida u obrazovnom procesu
Authors: Koca Saša , Radžo Alibegović Dženana
Published: July 2024

Prema podacima Svjetske zdravstvene organizacije, samo su dvije bolesti značajne u dječjoj dobi koje bi zadovoljile kriterije probira opravdane u medicinskom i ekonomskom smislu: prije svega ambliopija ili slabovidnost, a zatim oštećenje sluha. Za razliku od skrininga na oštećenje sluha, koji se već dugo provodi na Klinici za uho, grlo, nos KB Tuzla odmah po rođenju djeteta, skrining na ambliopiju se provodi periodično, točnije u sklopu projekata. Ambliopija je najčešća patologija vida u djece i vodeći je uzrok monokularne sljepoće. Ako se ne prepozna i ne liječi u ranom razdoblju djetetovog životnog razvoja, slabovidno oko više nikada neće moći dobro vidjeti, odnosno može postati funkcionalno slijepo. Sve navedeno od nemjerljive je važnosti za odgoj i obrazovanje djece oštećena vida. Pažljivim pregledom i procjenom vida tijekom redovitih sistematskih pregleda u primarnoj zdravstvenoj zaštiti djece pedijatar može otkriti rizične čimbenike za razvoj slabovidnosti, međutim ako prođu nezapaženo, to će se svakako odraziti na vizualnu oštrinu i dalji odgojno-obrazovni proces. Odgojno-obrazovni proces slabovidne djece zahtijeva multidisciplinarni pristup i timski rad kako nastavnog osoblja tako i edukatora-rehabilitatora, tiflologa, zatim roditelja i svakako djeteta koje pohađa odgojno-obrazovni proces prema prilagođenom planu i programu uz uključivanje u redoviti odgojno-obrazovni proces. Idealno bi bilo da se oštećenje vida otkrije najkasnije do šeste godine života, s obzirom na to da se razvoj vizualne oštrine završava do 7. godine života pri polasku u školi.
Copaiba oil on dentistry: a scoping review
Authors: Lima Cássia Cunha de , Barbosa Maria Helena Rocha , Guiotti Aimeé Maria , Gonçalves José Guilherme Pereira , Goiato Marcelo Coelho , Ribeiro Rayssa , Veiga Junior Valdir Florêncio da , Santos Daniela Micheline dos
Published: July 2024

Copaiba oil is a natural product commonly employed in traditional medicine due to qualities as anti-inflammatory and antimicrobial mainly. On dentistry, studies have focused on the use of copaiba in cavity varnishes, endodontic cements, bacterial biofilm control and even in the composition of local anesthetics. The aim of this study was to investigate on the use of copaiba oil within dental specialties. The search was conducted on databases using the primary keywords ‘Copaifera’ and ‘Dentistry’ resulting in 687 studies. Was observed that Copaifera multijuga was the most prevalent species in the evaluated articles, endodontics was the most presente dental specialty in publications. Antimicrobial tests and biocompatibility tests was most prevalents. Based on the results of this study, despite the limited number of evaluated works, it can be concluded that over the years, copaiba has been increasingly used in dentistry, yielding promising results such as the development of new bioproducts that combine copaiba's pharmacological characteristics without compromising the necessary physical attributes for clinical use.
Bioactivity of hydrolysates obtained from buffalo caseinate using macambira (Bromelia laciniosa L.) proteases
Authors: Silva Dafné , Silva Izaqueu , Barbosa José , Santos Wellington , Leite Tonny , Moreira Keila , Sena Amanda Reges de
Published: July 2024

Bromelain refers to a set of proteases with the ability to break peptide bonds, presenting several industrial applications. The present work aimed to obtain and evaluate protein hydrolysates from buffalo casein after the action of bromelain extracted from macambira (Bromelia laciniosa). Proteolytic activity was determined using azocasein as substrate. Total protein was determined using the Lowry method. The enzyme extract was partially purified and protein hydrolysates were obtained from buffalo caseinate through experimental design. It was found that bromelain promoted hydrolysis that varied between 14.47 and 19.43% and only the caseinate concentration was significant in the experimental field studied. All hydrolysates showed antioxidant activity by two methods used. The hydrolysates obtained did not show antimicrobial activity against the microorganisms tested. The bromelain obtained has the potential to obtain protein hydrolysates, with antioxidant activity, which can, after further studies, be added to functional foods.
Palliative care in patients with diabetes mellitus: integrative review
Authors: Timóteo Francina Silva , Costa Gabriel , Donega Gustavo Vieira , Sakamoto Nicole Yoshie Gonçalves , Souza Mariana Cristina dos Santos
Published: July 2024

Objective: To synthesize scientific publications related to palliative care for patients with Diabetes Mellitus. Method: Integrative Review guided by the question “‘what is the influence of palliative care on the comfort, quality of life and glycemic control of patients with DM1 and DM2?”. Articles published in the last ten years (2013-2023), in 8 libraries and databases, were reviewed. Results: After searching and applying the inclusion and exclusion criteria, 6,443 were found and, after the screening and eligibility steps, 3 were included for analysis. Four thematic classes emerged: Reluctance and taboo in Palliative Care; Glycemic control and quality of life; Family and professional involvement; Reception and Health Care Networks in the context of Diabetes Mellitus. Conclusion: It is emphasized how beneficial early adherence to palliative care can be for a diabetic patient, aiming for better comfort and quality of life. Some factors limited the referral of these patients to palliative care: patient and family acceptance, resource limitations in palliative care programs and difficulties in pathological prognosis. Encouraging research related to this topic would significantly strengthen the debate on effective reception and better monitoring in palliative care.
Visual diagnosis of açaí trees under soilless cultivation in the Amazon
Authors: Silva André Luiz Pereira da , Silva Breno Marques da Silva e , Lima Junior Joaquim Alves de , Sena Welliton de Lima
Published: July 2024

The açaí tree culture is extremely important for the Northern Region of Brazil, therefore, the aim of this work was to evaluate the nutritional status through visual diagnosis of açaí tree leaves. Therefore, the objective of the work was to analyze the development of açaí seedlings, with the omission of macro and micronutrients, characterizing the visual symptoms observed on the leaves of the plants, in this case only for N, P and K. The study was carried out in a greenhouse, which is located at the Federal Institute of Pará (IFPA), Campus Castanhal – PA. A completely randomized experimental design (DIC) was used, with 11 treatments and 5 replications, totaling 55 experimental units. The treatments were: Complete treatment (With all nutrients), Omission of Nitrogen (-N), Omission of Phosphorus (-P), Omission of Potassium (-K), Omission of (-Ca), Omission of Magnesium (-Mg ), Sulfur Omission (-S), Iron Omission (-Fe), Zinc Omission (-Zn), Boron Omission (-B) and Copper Omission (-Cu). The results after application were that the characterization of the visual symptoms of deficiencies that were evident in the leaves of the açaí seedlings, a limitation in the development of the seedlings was observed.
Histomorphological spectrum of uterine leiomyoma and its secondary changes
Authors: Kale Vidya G , Deore Bharati S , Nathe Neha S , Phadol Jyoti N , Meher Akshaya P
Published: July 2024

Aim and Background: Leiomyoma is one of the most common causes for abnormal uterine bleeding in females. Furthermore, sometimes leiomyoma is clinically, radiologically, and histologically believed to be malignancy. Thus, there is a need for more studies to know the different variants and secondary changes occurring in leiomyoma. Methods: This study was carried out at the Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital, and Research Centre. Over a period from January 2019 to June 2023, 355 cases were received and included in this study. The specimen was examined grossly, processed, stained, and studied microscopically. Results: In the current study, cellular leiomyoma was the most common variant and the hyaline degeneration was the most common secondary change identified. Conclusion: The current study gives insights into the clinicopathologic spectrum of uterine leiomyoma along with their clinical presentation, variants and associated secondary changes, in comparison with the findings from similar studies of different areas.
Pendampingan Pembuatan Dompok Durian di Desa Tampumia, Kabupaten Luwu
Authors: Sunarni Yassa  , Marlina Bakri  , M. Nur Hakim  , Gita Srihidayati  , Suparman Suparman
Published: July 2024

Buah durian mempunyai banyak manfaat yang mengandung senyawa yang di butuhkan oleh tubuh manusia, karena dalam durian mengandung beberapa nutrisi penting, diantaranya: Kalori, Lemak, Karbohidrat, Serat, Protein, Vitamin, Tiamin, Mangan, Vitamin, Kalium, Kalsium, Zat besi, Riboflavin, Tembaga, Folat, Magnesium, Niasin. Sehingga buah durian dapat mendukung kesehatan tubuh secara menyeluruh karena dapat mencegah perubahan sel abnormal kanker, meningkatkan kesehatan pencernaan, mencegah munculnya nyeri, mencegah penuaan dini, menjaga kesehatan tulang, mencegah penyakit jantung, mengatur tekanan darah, mencegah diabetes, mencegah anemia, mengatasi insomnia, meningkatkan kesehatan kulit, mencegah depresi, mengatasi disfungsi seksual. Kemudian sebagai kuliner durian dapat dibuat menjadi ‘Dompok’ yang dapat menjadi cemilan manis di Palopo, serta Dompok juga kerap dijadikan sebagai salah satu oleh-oleh khas yang digemari banyak orang. Karena selain memiliki cita rasa yang enak dan legit, harga dompok durian juga relatif terjangkau, penjual dompok pun juga mudah ditemukan di toko-toko oleh-oleh di pasar tradisional
Pemeriksaan Anti-Rhesus pada Golongan Darah Mahasiswa D4 TLM Angkatan 2022 Kelas A di Universitas Megarezky Makassar
Authors: Runimeirati
Published: July 2024

Pemeriksaan Anti-Rhesus pada golongan darah A, B, AB, O menggunakan reagen Rh. Penelitian ini bertujuan untuk mengetahui apakah jenis Rhesus yang dimiliki mahasiwa kelas A Angkatan 2022 PRODI D-IV TEKNOLOGI LABORATIUM MEDIK, Jika Rhesusnya postif (+) ditandai dengan terjadinya prinsip aglutinasi pada darah dan geagen yang telah dihomogenkan yang menimbulkan tekstur seperti pasir, sedangkan jika Rhesusnya negative (-) ditandai dengan tidak terjadinya prinsip aglutinasi pada darah dan Reagen yang telah dihomogenkan. Data di olah dengan menggunakan metode slide dari anak kelas A Angkatan 2022 PRODI D-IV TEKNOLOGI LABORATURIUM MEDIK (TLM).
Meningkatkan Aksesibilitas dan Efisiensi Layanan Publik Melalui Program Pengaduan Online di Desa Paomacang Kecamatan Sukamaju Selatan
Authors: Iin Indrianto  , Zidan Ramdhan  , Kasih Nur Cahaya  , Besse Herdiana  , Haspida Nur
Published: July 2024

Desa Paomacang di Kecamatan Sukamaju Selatan masih menghadapi kendala dalam aksesibilitas dan efisiensi layanan publik. Hal ini disebabkan oleh beberapa faktor, seperti jarak tempuh yang jauh ke kantor desa, keterbatasan waktu masyarakat, dan kurangnya informasi tentang layanan yang tersedia. Penelitian ini bertujuan untuk meningkatkan aksesibilitas dan efisiensi layanan publik di Desa Paomacang melalui program pengaduan online. Program ini memungkinkan masyarakat untuk menyampaikan pengaduan dan keluhan tentang layanan publik secara online melalui platform website dan aplikasi mobile. Penelitian ini menggunakan pendekatan partisipatif. Program pengaduan online dirancang dan diimplementasikan dengan melibatkan masyarakat secara aktif. Hasil penelitian menunjukkan bahwa program pengaduan online efektif dalam meningkatkan aksesibilitas dan efisiensi layanan publik di Desa Paomacang.
Yield advantage and profitability of selected climate-smart technologies: Findings from demonstration plots in Northern Uganda
Authors: Okao Moses ,   Department of Crop Science and Agroforestry, Faculty of Tropical AgriSciences, Czech University of Life Sciences, Prague-Suchdol, Czech Republic, Godfrey Otim Anyoni , Mutonyi Gloria , Ogwal Lawrence , Komakech Alfred , Frank Turyagyenda Laban , Bharati Rohit ,   Ngetta Zonal Agricultural Research and Development Institute, National Agricultural Research Organisation, Lira, Uganda,   Ngetta Zonal Agricultural Research and Development Institute, National Agricultural Research Organisation, Lira, Uganda,   Ngetta Zonal Agricultural Research and Development Institute, National Agricultural Research Organisation, Lira, Uganda,   Project for the Restoration of Livelihoods in Northern Region (PRELNOR), Gulu Regional Branch, Ministry of Local Government, Kampala, Uganda,   Ngetta Zonal Agricultural Research and Development Institute, National Agricultural Research Organisation, Lira, Uganda,   Department of Crop Science and Agroforestry, Faculty of Tropical AgriSciences, Czech University of Life Sciences, Prague-Suchdol, Czech Republic
Published: July 2024

Climate-smart agriculture (CSA) is viewed as a potentially effective intervention to address low agricultural productivity in Sub-Saharan Africa (SSA), while strengthening farmers’ capacity to adapt to the effects of climate change. We therefore conducted a study to examine maize yield response to three CSA practices – ripping, permanent planting basins and alley cropping. The profitability of their use with and without fertiliser application was also evaluated. It was deduced from the study that ripping, planting basins and alley cropping with Gliricidia (Gliricidia sepium) gave the greatest yield advantageof 457.1 kg/acre, 456.7 kg/acre and 437.2 kg/acre respectively. Fertiliser application significantly increased the yield advantage, but this increment did not necessarily translate into cost-effectiveness due to the associated costs. In fact, minimum tillage interventions were more profitable without fertiliser application, and at some locations responded poorly to fertiliser application. These variable responses indicate the need for developing site-specific CSA interventions for improved maize productivity and profitability.
Effect of participation in goat keeping on household food security:A case study of Dowa district, Malawi
Authors: Kachingwe Lovemore M ,   Department of Agricultural and Applied Economics, Bunda College, Malawi, Mangisoni Julius H , Katengeza Samson P , Kachule Richard ,   Department of Agricultural and Applied Economics, Bunda College, Malawi,   Department of Agricultural and Applied Economics, Bunda College, Malawi,   Department of Agricultural and Applied Economics, Bunda College, Malawi
Published: July 2024

Goat keeping is a common practice among rural farmers due to the adaptability of goats to harsh environments, their efficient forage conversion and rapid growth, and their multiple benefits, including the production of manure and high-quality milk. However, limited research has been done on the direct effect of participation in goat keeping on food security in Malawi. Therefore, this study investigated the effect of participation in goat keeping on household food security in Dowa district in Malawi using the propensity score-matching technique. The results reveal a positive correlation between goat farming and household food security. This was evident from the significant average treatment effect on the treated (ATT), which indicated a lower value of the Household Food Insecurity Access Scale (HFIAS) for goat keepers compared to non-keepers. These findings highlight the potential of goat farming to enhance food security among rural households, emphasising the importance of promoting this type of farming at the household level.
Peran Artificial Intelligence Dalam Transformasi Sumber Daya Manusia Pendidikan: Peningkatan Kualitas Vs Penggantian
Authors: Wakhidah Esti Nur , Sulaeman Maman , Metris Diksi , Priambodo Aji , Prakoso Riyan Dwi Yulian
Published: July 2024

Artificial Intelligence (AI) sangat penting untuk mempersiapkan sumber daya manusia (SDM) dalam menghadapi perubahan yang cepat dan dinamis di dunia kerja. AI adalah teknologi yang semakin berkembang dan digunakan dalam berbagai sektor, termasuk pendidikan. Pendidikan harus beradaptasi dengan perkembangan teknologi AI dan memanfaatkannya untuk meningkatkan kualitas pembelajaran. Tujuan penelitian ini untuk menganalisis pendidikan di era AI apakah dapat meningkatkan kualitas sumber daya manusia atau menggantikannya. Metode penelitian yang diguanakan pada penelitian ini adalah literatur review. Hasil penelitian menunjukkan bahwa walaupun teknologi AI dapat membantu dalam mengoptimalkan pembelajaran, sumber daya manusia dalam bidang pendidikan tetap sangat diperlukan. Keterampilan manusia dalam kreativitas, empati, komunikasi, dan pemecahan masalah masih sangat penting dalam menciptakan pengalaman pembelajaran yang efektif dan menyenangkan bagi siswa.
Pengaruh Aset, Ekuitas, Dan Liabilitas Terhadap Laba Perusahaan Sub Sektor Perbankan Yang Terdaftar Di Bursa Efek Indonesia Tahun 2021-2022
Authors: Nisa Afifatun , Yulianisa Dwi , - Marsela , Pramudiah Ilham , Saputra Ogi
Published: July 2024

Tujuan penelitian ini yaitu untuk mengetahui pengaruh aset, ekuitas, dan liabilitas terhadap laba perusahaan subsektor perbankan yang terdaftar di Bursa Efek Indonesia. Penelitian ini menggunakan data sekunder yang bersifat kuantitatif. Metode analisis yang digunakan yaitu analisis regresi data panel dengan menggunakan aplikasi Eviews12. Populasi dalam penelitian ini adalah perusahaan subsektor perbankan yang terdaftar di Bursa Efek Indonesia selama dua tahun (2021-2022). Sedangkan sampel yang digunakan dalam penelitian ini adalah 20 perusahaan sektor keuangan yang terdaftar di Bursa Efek Indonesia selama dua tahun (2021-2022). Hasil penelitian dengan pengujian hipotesis menguanakan uji statistic t menunjukan bahwah rasio aset dan liabilitas berpengaruh tidak signifikan terhadap laba,sedangkan ekuitas berpenggaruh signifikan terhadap aset.
Analisis Pengaruh Jumlah Umkm Dan Tenaga Kerja Terhadap Pertumbuhan Ekonomi Kabupaten/Kota Di Provinsi Jambi Periode 2021–2023
Authors: Husen Muhamad , Mubarak Dzaki , Rusmanto Hendi , Wahyudi Muhamad Insan , Oktavia Dini , Saputra Ogi
Published: July 2024

Pertumbuhan ekonomi Indonesia dalam beberapa tahun terakhir menunjukkan fluktuasi, yang menjadi perhatian penting bagi pemerintah dalam upaya menstabilkan ekonomi baik di tingkat nasional maupun daerah. Penelitian ini bertujuan untuk mengevaluasi dampak jumlah UMKM dan tenaga kerja terhadap peningkatan ekonomi di Kabupaten/Kota Provinsi Jambi pada tahun 2021-2023. Sampel penelitian mencakup 11 Kabupaten/Kota di Provinsi Jambi, dipilih melalui metode random sampling. Data yang digunakan adalah data sekunder dari Badan Pusat Statistik. Hasil analisis menunjukkan bahwa jumlah UMKM tidak memiliki pengaruh signifikan terhadap perekonomian Provinsi Jambi, sementara jumlah tenaga kerja secara parsial memiliki pengaruh signifikan. Secara keseluruhan, variabel bebas tidak mempengaruhi variabel terikat secara simultan. Variabel bebas hanya menjelaskan 13% dari variabel terikat, sementara sisanya dipengaruhi oleh variabel lain yang tidak dibahas dalam studi ini.
Aspectos gerais sobre o tratamento e complicações da apendicite aguda: análise abrangente de literatura
Authors: Linhares Mateus Rodrigues , Oliveira Gabriella Mendonça Leão de , Godoy André Brasil Cardoso de , Ruy Bruna Tainah , Pereira Sarah Diniz , Moreira Brenda Rafaela Cordeiro , Sodré Rhaissa Carvalho , Nogueira Ana Beatriz Silveira , Oliveira Vitória Beatriz Secchinatto Brito , Santos Neto Nilo Gonçalves dos , Almeida Luisa Gabriela Português , Filgueira Rayssa Nascimento , Santos Felippo Ataide dos , Duarte Aline Cristina , Rodrigues Thales do Vale , Demeneghi Maria Lara Beraldo
Published: July 2024

A apendicite aguda (AA) é uma inflamação aguda do apêndice, podendo ser classificada como “não complicada” ou “complicada”. A forma não complicada é definida como inflamação na ausência de gangrena, fluido purulento livre ou abscesso. Já a complicada é acompanhada por todas essas características inflamatórias, com ou sem perfuração. Essa patologia é a causa mais comum de abdome agudo, e tem uma incidência maior em homens do que em mulheres, com estas últimas tendo um risco maior de passar por apendicectomia. Assim, com o crescente corpo de literatura sobre a apendicite aguda, seu tratamento e suas possíveis complicações, foi possível a realização de uma revisão integrativa de literatura por meio da plataforma pubmed, com seleção e análise criteriosa dos artigos, a fim de revisar e analisar as evidências atuais sobre o impacto do tratamento da AA e de suas complicações e consequências para os pacientes. Nesta revisão foi identificado que existem diversos tipos de tratamento para a apendicite aguda, como o tratamento conservador com antibióticos; apendicectomia, aberta ou videolaparoscópica; tratamento associando cirurgia e antibioticoterapia; e até o tratamento endoscópico. Ademais, foram analisadas as complicações e consequências da AA em relação ao tipo de tratamento adotado, portanto, não houve diferença significativa na taxa de complicações após o tratamento em participantes tratados com antibióticos em comparação com aqueles que foram randomizados para a apendicectomia. Logo, os estudos mostraram que não houve diferença significativa nas complicações pós-tratamento.
Análise geral sobre a gestão de doenças crônicas: revisão de literatura
Authors: Pontes Melliza Barbosa , Linhares Mateus Rodrigues , Vasconcelos Laís de Lima , Espírito Santo Giovanna Lopes do , Andrade Geovana Fernandes , Castro Ana Luiza , Souza Fernanda Guimarães de , Nogueira Ana Beatriz Silveira , Ribeiro Júnior José Ronilson Carlos , Oliveira Gabriella Mendonça Leão de , Santos Felippo Ataide dos , Durão Gabriel Gonçalves , Gomes Bernardo Tanure , Demeneghi Maria Lara Beraldo , Duarte Aline Cristina , Sales Ana Beatriz Coelho
Published: July 2024

A gestão de doenças crônicas é crucial para melhorar a qualidade de vida dos pacientes e reduzir custos de saúde globais. Estratégias integradas, como cuidados primários coordenados e tecnologias de saúde, são essenciais, entretanto, barreiras como fragmentação do sistema de saúde e desigualdades socioeconômicas persistem. Contudo, a integração de tecnologias avançadas e cuidados centrados pode transformar a gestão de doenças crônicas, promovendo melhores resultados e qualidade de vida. Assim, com o crescente corpo de literatura sobre a gestão de doenças crônicas, como diabetes e hipertensão, foi possível a realização de uma revisão integrativa de literatura por meio da plataforma pubmed, com seleção e análise criteriosa dos artigos, a fim de revisar e analisar as evidências atuais sobre o impacto e a necessidade de se ter uma gestão de doenças crônicas para um melhor prognóstico aos pacientes. Nesta revisão foi possível concluir que gerir as doenças crônicas é um desafio crescente para os sistemas de saúde globalmente. Desse modo, este artigo revisou estratégias como a telemedicina e a autogestão do paciente, destacando sua eficácia na melhoria dos resultados de saúde. A pandemia de COVID-19 acelerou a adoção de tecnologias digitais, mas também evidenciou desafios como resistência cultural e desigualdades socioeconômicas. Logo, superar esses obstáculos requer políticas públicas robustas e investimentos em infraestrutura. Portanto, abordagens integradas que combinem cuidados diversificados e tecnologias inovadoras são essenciais para promover um sistema de saúde sustentável e centrado no paciente, melhorando assim a qualidade de vida e reduzindo custos associados ao tratamento de complicações crônicas.
Atualizações sobre o tratamento e complicações da colecistite aguda: uma revisão de literatura
Authors: Linhares Mateus Rodrigues , Godoy André Brasil Cardoso de , Ruy Bruna Tainah , Pontes Melliza Barbosa , Oliveira Gabriella Mendonça Leão de , Pereira Sarah Diniz , Moreira Brenda Rafaela Cordeiro , Sodré Rhaissa Carvalho , Paula Carla Queiroz Fernandes de , Oliveira Vitória Beatriz Secchinatto Brito , Santos Neto Nilo Gonçalves dos , Almeida Luisa Gabriela Português , Teodoro Clarice Rodrigues , Rodrigues Thales do Vale , Gomes Bernardo Tanure , Fernandes Jacob Ricardo Pereira de Carvalho
Published: July 2024

A Colecistite Aguda (CA) é uma doença inflamatória da vesícula biliar com fisiopatologia na obstrução da via de drenagem ou na dismotilidade das paredes da vesícula, condicionando aumento da pressão intraluminal, edema da parede, alteração da vascularização com isquemia ou necrose, proliferação bacteriana e perfuração do mesmo. É possível classificar a gravidade da doença em leve (grau I), moderada (grau II) e grave (grau III). Assim, com o crescente corpo de literatura sobre a colecistite aguda, seu tratamento ideal e suas possíveis complicações, foi possível a realização de uma revisão integrativa de literatura por meio da plataforma pubmed, com seleção e análise criteriosa dos artigos, a fim de revisar e analisar as evidências atuais sobre o impacto do tratamento da CA e de suas complicações e consequências para os pacientes. Nesta revisão foi identificado que existem diversos tipos de tratamento para a colecistite aguda, incluindo colecistectomia laparoscópica (LC) e aberta com ou sem exploração do ducto biliar, colangiografia retrógrada endoscópica e pancreatografia (CPRE), colecistostomia percutânea, colecistectomia subtotal, e até tratamento endoscópico. Assim, foram analisadas as complicações da CA em relação ao tipo de tratamento adotado. Dessa maneira, quanto às complicações, conclui-se que a drenagem percutânea tem sido associada a taxas de mortalidade semelhantes às da colecistectomia, e o tratamento conservador com ou sem drenagem percutânea não afeta a doença do cálculo biliar subjacente. Portanto, as consequências mais comuns são o empiema e a perfuração espontânea da vesícula biliar, os quais são fruto de uma colecistite não resolvida.
Propriedades mecânicas de argamassas sustentáveis, utilizando resíduos de celulose, cinza volante e lama de cal, da Amazônia, em substituição parcial do clínquer
Authors: Silva Kleber Roberto Matos da , Fernandez Oscar Jesus Choque , Cunha Rodrigo Rodrigues da , Picanço Marcelo de Souza
Published: July 2024

As indústrias cimentícias são responsáveis pela emissão de 8% do CO2 lançado na atmosfera global, provenientes da reação química envolvida na produção do clínquer, razão pela qual busca alternativas para mitigar esse passivo ambiental. Esta pesquisa tem por objetivo analisar as propriedades mecânicas de argamassas sustentáveis, utilizando resíduos de celulose, cinza volante e lama de cal, da Amazônia, em substituição parcial do clínquer, a partir da otimização de misturas cimentícias para obter argamassas com características de resistência e fluidez comparáveis ​​à argamassa de referência de cimento Portland comum. As misturas cimentícias utilizadas foram obtidas através de composições binárias e ternárias com o clínquer, sendo a cinza volante utilizada como material pozolânico e a lama de cal como material carbonático. As composições químicas das misturas foram determinadas por espectrometria de fluorescência de raios-X (FRX) e a determinação das fases presentes foram realizadas através de análises mineralógicas por difração de raios-X (DRX). As misturas foram caracterizadas no tocante a granulometria a laser, massa específica, área superficial e consistência. As propriedades mecânicas foram determinadas através da moldagem de corpos de prova cilíndricos para verificar a resistência à compressão. As resistências à compressão variaram de 55% a 103% em relação à argamassa de referência aos 28 dias e 73% a 105% aos 91 dias, comprovando a viabilidade do uso de lama de cal e cinzas volantes como adições minerais para misturas cimentícias, com menor consumo de clínquer, reduzindo custos, promovendo a economia circular com o aproveitamento de resíduos, que seriam descartados em aterros sanitários.
A new approximation to the first order fractional derivative in the Caputo-Fabrizio sense using Haar Wavelet integration formula
Authors: Dehda Bachir , Gao Jianqiang
Published: July 2024

Decades ago, fractional calculus arose to generalize ordinary derivation and integration, and then became a means of modeling and interpreting many phenomena in various fields such as engineering, physics, chemistry, biology and signal processing. The definition of the fractional derivative began with a derivative with a singular kernel, such as the Riemann-Liouville and Caputo derivative. Due to the singularity of the kernel, the definition of Caputo-Fabrizio appeared, which has a non-singular kernel and mathematical properties similar to the derivative of the integer order. This last definition attracted many mathematicians and researchers to use it in modeling phenomena and obtaining historical information about the development of the studied phenomena, but usually the analytical solution does not exist, which necessitated numerical methods to find an approximate solution. These approximate methods depend on finding an approximate formula for the fractional derivative, and then the problem is transformed into a system of algebraic equations that is easy to solve. In fact, all the numerical methods that have been used have a polynomial rate of convergence, which calls for thinking about a new method that is more effective and has a better rate of convergence.  For this reason, in this paper, we propose an efficient numerical method to approximate the first order fractional derivative in the Caputo-Fabrizio sense. This method develops a new quadratic formula using Haar wavelet integration method. Error analysis of our proposed method gives an exponential convergence rate of  . To check the effectiveness of the proposed method, we examine some examples with different fractional orders. The quantative results demonstrated the stability and efficiency of the proposed method.
Exploring the relationship between gut microbial ecology and inflammatory disease: An insight into health and immune function
Authors: Marik Akashlina , Biswas Saheli , Banerjee Ena Ray
Published: July 2024

The immune system, host brain development, and general metabolism are all influenced by the gut bacteria. Bacteria make up the majority of the gut microbiota in mammals. The mouse has been the most often used animal model in preclinical biological research. In mice, Firmicutes and Clostridiales are prominent. On the other hand, Bacteroidaceae , Prevotellaceae , and Firmicutes are commonly found in humans. In this review, we performed a detailed study by focusing on a comparison between human and murine gut microbiomes, role of the microbiome and their secreted metabolites in regulating gut immunity to maintain homeostasis, and changes in the microbial composition in the dysbiotic state.
COMPARATIVE EFFICACY OF INTRACORONARY VERAPAMIL AND ADRENALINE IN MANAGING CORONARY NO-REFLOW DURING PRIMARY PCI IN STEMI PATIENTS AT A TERTIARY CARE HOSPITAL
Authors: KHAN S , REHMAN SU , SAJJAD W , BEGUM S , YASMIN R , ADIL IU
Published: July 2024

Coronary No-Reflow (CNR) is a significant complication during Primary Percutaneous Coronary Intervention (PPCI) for ST-Elevation Myocardial Infarction (STEMI), often leading to poor clinical outcomes. Management strategies for CNR include various pharmacological agents, among which intracoronary verapamil and intracoronary adrenaline are commonly used alongside Glycoprotein IIb/IIIa inhibitors. Objective: This study aims to compare the effectiveness of intracoronary verapamil versus intracoronary adrenaline, alongside Glycoprotein IIb/IIIa inhibitors, in managing Coronary No-Reflow (CNR) during Primary Percutaneous Coronary Intervention (PPC1) for STEMI patients. Methodology: This randomized-control-trial was conducted at the Department of Cardiology, MTI Lady Reading Hospital Peshawar, Pakistan, from May 2023 to April 2024. Fifty patients diagnosed with CNR during PPC1 were randomised into two groups: adrenaline and verapamil. The primary outcome measures were TIMI Flow Grade (TFG) and Myocardial Blush Grade (MBG) immediately post-intervention. In contrast, secondary outcomes included Major Adverse Cardiovascular Events (MACE), myocardial infarction, stroke, target vessel revascularisation, mortality, and Left Ventricular Ejection Fraction (LVEF) assessed at baseline and one-month follow-up. Statistical analyses were performed using IBM SPSS version 20, with significance at P<0.05. Results: Baseline characteristics, procedural details, and initial TIMI flow grades were similar between groups. Adrenaline achieved universal TIMI 3 flow compared to 84% with verapamil (p=0.049), but no significant differences were noted in myocardial blush grades. Adrenaline led to significantly higher follow-up LVEF (45.0 ± 9.0 vs. 39.0 ± 9.0, p=0.027) and a more significant percentage change in LVEF (20.97% vs. 8.94%, p=0.042) than verapamil. Adverse event rates were comparable except for lower MACE incidence at 30 days with adrenaline (8.0% vs. 24.0%, p=0.039). Conclusion: Adrenaline notably enhanced TIMI 3 flow rates, improved left ventricular ejection fraction, and decreased significant adverse cardiovascular events at 30 days compared to verapamil. These findings suggest that adrenaline may be a superior option for improving coronary blood flow and early clinical outcomes in this patient population.
THE LEVEL OF ANTI-TPO ANTIBODIES IN IBD PATIENTS: A CASE SERIES
Authors: RAHMAN AA , WAQAS M , MOHSIN Z , HAMEED Z , JUNAID M , SHERBANO . , SIRI G
Published: July 2024

Inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), are chronic conditions characterized by intestinal inflammation. Autoimmune thyroid diseases (AITDs), such as those involving anti-thyroid peroxidase (anti-TPO) antibodies, have been noted as common comorbidities in IBD patients. Despite this, comprehensive data on anti-TPO antibodies' prevalence and clinical significance in IBD, particularly about disease type and location, remain limited. Objective: This study aims to determine the prevalence of anti-TPO antibodies among patients with IBD, primarily focusing on UC, and to compare these findings with the prevalence of anti-TPO antibodies in the general Iranian population. Methods: A cross-sectional study was conducted at Amir Alam Hospital, Tehran University of Medical Sciences, in 2022. The study included 98 patients diagnosed with IBD, using convenient sampling. Gender, age, anti-TPO levels, Free T4, and TSH were measured through questionnaires, serological tests, and imaging. Statistical analyses involved descriptive statistics, Chi-square tests, Pearson correlation coefficients, independent samples t-tests, and ANOVA, performed using SPSS software. Results: No significant differences were observed in anti-TPO levels between genders (p = 0.844). Additionally, no significant difference was found in Free T4 and TSH levels based on gender (p = 0.396 and p = 0.260, respectively). A significant correlation was identified between TSH levels and disease location (p < 0.05), while anti-TPO levels showed no significant correlation with disease type or location. Conclusion: The prevalence of anti-TPO antibodies in IBD patients was notable, with no significant differences observed between UC and CD or between genders. The study underscores the importance of regular thyroid function monitoring in IBD patients, particularly considering the significant association between TSH levels and disease location. Further research is needed to explore the underlying mechanisms and clinical implications of thyroid dysfunction in IBD.
Assessment of the Knowledge and Practice on Safe Handling of Anticancer Drugs among Pharmacists in Iraqi Healthcare Settings
Authors: Khadim Mayada Qasim , Kadhim Dheyaa Jabbar
Published: July 2024

Background: Occupational exposure to hazardous drugs occurs in all aspects of anticancer drug handling. Proper recommendations and guidelines should be applied to control and reduce exposure. Objective: To assess pharmacists' knowledge and practice regarding the safe handling of anticancer drugs. Methods: A cross-sectional study was conducted at seven major hospitals in Baghdad City, Iraq, from December 2023 to February 2024. A pre-designed questionnaire was given to pharmacists who handled anticancer drugs in chemotherapy units. The questionnaire comprises sociodemographic data, knowledge of the safe handling of cytotoxic drugs and thoughts about exposure and risk, practices for safely handling cytotoxic drugs, and challenges for safely handling cytotoxic drugs. Results: A total of 126 pharmacists were enrolled in the study. Less than half of the participants (46%) received training on anticancer drugs. While more than a third (42.9%) of the pharmacists were handling more than 100 cytotoxic preparations weekly, the total knowledge score was 7.14, while the total practice score was 73.36, with less than half of the pharmacists having good knowledge (44.44%) or practice (48.41%). Pharmacists who received training had significantly higher total practice scores than those who did not. Pharmacists with more than 100 weekly preparations were more knowledgeable than those with 50–99 preparations. Conclusions: The majority of participating pharmacists had fair to excellent knowledge and practice regarding the safe handling of cytotoxic medications. However, there were some gaps regarding important knowledge and practice issues. To improve knowledge and practices regarding anticancer handling, training is necessary.
Welkom in mijn wereld: ondersteuningsbehoeften van ouderen met een verstandelijke beperking
Authors: Thalen Marloes
Published: July 2024

Mensen met een verstandelijke beperking worden steeds ouder door verbeterde levensomstandigheden en betere medische zorg. Dit komt overeen met de toenemende vergrijzing in de algemene bevolking. Hoewel de levensverwachting van zowel mensen met als zonder verstandelijke beperking toeneemt, verschilt het verouderingsproces van mensen met een verstandelijke beperking van dat van ouderen in de algemene bevolking. Het verouderingsproces van mensen met een verstandelijke beperking begint vaak al vanaf de leeftijd van 50 jaar. Bij mensen die functioneren op (zeer) ernstig verstandelijk beperkt niveau of mensen met downsyndroom, kan veroudering zelfs al vanaf de leeftijd van 40 jaar optreden. Daarnaast hebben ouderen met een verstandelijke beperking een verhoogd risico op het ontwikkelen van gezondheidsproblemen, zoals diabetes, depressie, obesitas, visuele beperkingen, slikproblemen, angststoornissen en dementie.
Micro Study on the Impact of the Digital Economy on Income from the Perspective of Labor Matching
Authors: Li Yuxuan , Wang Xintao
Published: July 2024

As the digital economy continues to develop, the socio-economic structure and lifestyle have undergone significant changes, which have had a profound impact on the labor market. To explore the mechanism of the digital economys impact on income, this study builds a personal panel data model from a micro perspective and conducts an empirical analysis. The matching situation of individuals in terms of employment and income is assessed through the skill-job matching degree and skill-income matching degree. A bidirectional fixed-effects model is used for calculation and analysis, comprehensively considering individual characteristics, skill levels, job requirements, and other factors. This study examines the direct and indirect effects of the digital economy on income and explores its influencing mechanisms.
Urgensi Pemberian Izin Pengelolaan Tambang bagi Organisasi Kemasyarakatan "Keagamaan" di Indonesia: Analisis Regulasi dalam PP Nomor 25 Tahun 2024
Authors: Prastika Amanda , Mutiara Fajriatul Izza Putri  , Viorelia Nabila Tasya
Published: July 2024

Government Regulation No. 25/2024 on the Amendment to Government Regulation No. 96/2021 on the Implementation of Mineral and Coal Mining Business Activities has sparked heated debate in Indonesia. One of the controversial points is the provision that allows religious community organizations to obtain mining business licenses, which is contrary to Law No. 3 of 2020 concerning Mineral and Coal Mining. The writing of this research uses normative legal research methods that emphasize in-depth study of laws and regulations that exist in society. This research was conducted to find out how the form of decisions on mass organizations that apply for licenses in PP No. 25 of 2024 and how efforts to apply for WIUPK by mass organizations according to PP No. 25 of 2024 and Law No. 3 of 2020. The research that will be outlined in the form of this article is entitled "The Urgency of Granting Mining Management Permits for "Religious" Mass Organizations in Indonesia: Regulatory Analysis in Government Regulation Number 25 of 2024" aims to examine these provisions in depth. This journal will analyze the urgency of granting mining permits for religious mass organizations, with an emphasis on the regulatory aspects contained in PP No. 25 of 2024.
Nutritionist’s Role in Dietary Management of Patients with Cancer
Authors: Amal Agila
Published: July 2024

This study is to know the effect of appropriate nutrition on developing the health of children with cancer during their treatment. Also, it is to investigate personal dietary counseling by a nutritionist to maintain body weight. and to prevent malnutrition compared to standard medical care. A cross-sectional study was conducted on 100 children with cancer aged from 1 to 15 years in Tripoli, Libya from 1 March to 30 August, 2023. The cross-sectional study also involved 100 parents of children with cancer aged from 23 to 68 years old. Results showed that about 51% of cases had leukemia and 70 % of cancers were hereditary. Most cases in stage II (47%) and 44% of cases underwent chemotherapy dose treatment. Before treatment, 20% of children with cancer had normal BMI and 40% were underweight. But, 49% of children with cancer gained weight after treatment and they ate hospital diet. There was a slight increase in the values of BMI before and after treatments. The values of the BMI measurements before and after cancer treatment were a statistically significant different (P=0.047). Endpoints were weight loss before treatment, Low BMI and malnutrition. Consequently, early and intensive individualized dietary counseling by a nutritionist help promoting healthy weight.
Manajemen Strategis Pengelolaan Sampah di Sekolah: Studi Tentang Pembentukan Karakter Peduli Lingkungan SMPN 13 Sijunjung
Authors: Gumsi Putri Eka , Hendriani Suswati
Published: July 2024

This study aims to evaluate the environmental care character formation program at SMPN 13 Sijunjung, describe effective strategies, and identify efforts to reduce plastic waste in schools. Using a descriptive qualitative method, the study involved the principal, vice principal, teachers, students, and parents. Data were collected through interviews, observations, and document reviews, analyzed using the Miles and Huberman model. The results show that environmental care characters have been formed through daily habits, supported by strategic school management including teacher training, socialization campaigns, curriculum integration, recycling facilities, collaboration with related parties, and periodic evaluations. This article is expected to increase environmental awareness and actions among junior high school students
Analisis Startegi Pemasaran dalam Meningkatkan Penjualan Blooming Bouquet di Kabupaten Bengkayang
Authors: Nilviana Juniarti , Atlantika Yeremia Niaga , Vuspitasari Benedhikta Kikky , Beni Sabinus
Published: July 2024

This research aims to find out marketing strategies to increase sales and develop blooming bouquet products. This research uses a descriptive method through a qualitative approach. The data collection techniques for this research are observation, interviews, and research documentation by means of interviews conducted in Bengkayang and its surroundings, there are several informants who will be interviewed, with 3 aspects of questions, the research results obtained are regarding marketing strategies in improving and developing Blooming products. bouquets use marketing strategies, there are several things that must be done by business actors, namely carrying out product innovations in terms of shapes and variants requested by consumers as well as displaying more attractive packaging.
Impact of Community Empowerment Training on Cadets' Work-Study Balance and Leadership Development in Jakarta's Maritime Education Institutions
Authors: Laksamana Boy
Published: July 2024

This qualitative study investigates the impact of community empowerment training on cadets' work-study balance and leadership development within Jakarta's maritime education institutions. Through in-depth interviews with 10 cadets engaged in internships alongside their academic studies, the study identifies key themes. These include the development of time management skills, enhancement of communication abilities, and opportunities for leadership growth facilitated by the training programme. Findings highlight the crucial role of practical skills development in equipping cadets to manage academic and professional responsibilities effectively. Recommendations for educational practices include integrating practical skills training, expanding leadership initiatives, fostering industry collaboration, implementing feedback mechanisms, and promoting lifelong learning among cadets and faculty. These initiatives aim to prepare cadets to meet the challenges of the maritime industry and contribute to its sustainable growth. The study contributes to enhancing educational strategies in maritime education and underscores the importance of holistic development in shaping future maritime leaders