bluuebunny/crossref_metadata_2025 huggingface dataset:
INTRACEREBRAL HAEMORRHAGE - THE LONG ODD OF MITRAL CLIP IMPLANTATION FOR MITRAL REGURGITATION - A CASE REPORT
Authors: Sanklecha Shika , ArjunDas Deepak
Published: September 2023

Mitral valve regurgitation is a disease attributable to defective closure of mitral valve, leading to back-
ow of blood across the valve. It is the commonest variant of valvular heart disease. In cases with severe
regurgitation, the circulating blood volume gets severely scarce, owing to regurgitation within left heart chambers. In
individuals over the age of 65, who are at high risk of surgical intervention, the Mitraclip technique is a successful and minimally
invasive treatment option for mitral regurgitation. However, despite FDA approval for the treatment of high-risk individuals with
primary mitral regurgitation (MR), neurological complications such as intracerebral haemorrhage (ICH), cardiac
complications like atrial brillation (AF) have been reported. The major goal of this case report is to draw attention to the
prospect of intracerebral haemorrhage (ICH) following mitraclip implantation. As of this case, A 78-year-old female with
multiple co-morbidities such as systemic hypertension and peripheral neuropathy presented with severe chest pain and was
found to have severe MR, severe pulmonary arterial hypertension, normal left ventricular function, an ejection fraction of 68%,
and underwent mitraclip implantation. The patient developed right occipital ICH following mitral clip implantation.
COMPARATIVE EVALUATION OF UREA NITROGEN LEVEL IN SERUM AND SALIVA OF CHRONIC KIDNEY DISEASE PATIENTS
Authors: Kuravatti Shilpa , Priscilla David Maria , Saxena Runjhun
Published: September 2023

Background and Objectives: Kidney disease is a worldwide public health problem, with increasing
incidence and prevalence, high costs, and poor outcomes. Chronic Kidney Disease involves an
irreversible loss of renal function. This results in increased Blood Urea Nitrogen (BUN) levels which may lead to high
concentration of salivary urea nitrogen (SUN) levels. BUN is directly related to the excretory function of the kidney. Salivary
based investigation provide an attractive alternative for blood, as it is a safe, noninvasive, cost effective technique for
screening, detection and monitoring of disease with good cooperation by patients. This study was undertaken to estimate and
correlate urea nitrogen levels in serum and saliva of CKD patients and to evaluate the use of salivary urea nitrogen as an
effective alternative biomarker to serum urea nitrogen in CKD patients. A total of 40 subjects comp Methods: rising of 20 healthy
controls (Group I) and 20 cases of CKD (Group II) were selected. The selected cases were clinically diagnosed and conrmed
cases of various stages of chronic kidney disease. 2ml of stimulated saliva and blood samples were collected from both the
groups. Using urease/glutamate dehydrogenase method, the concentration of urea nitrogen levels in serum and saliva was
evaluated. In the present study we found signicant correlation of serum urea nitrogen and salivary Results: urea nitrogen in
both controls and CKD cases. Serum urea nitrogen and salivary urea nitrogen were both increased in CKD cases. Serum urea
nitrogen and salivary urea nitrogen increased as CKD progressed. We therefore recommend, salivary u Conclusion: rea
nitrogen as a biomarker in CKD. We also recommend the use of salivary urea nitrogen as an alternative biomarker to serum
urea nitrogen in CKD. We suggest the use of salivary urea nitrogen to diagnose, stage and monitor management of CKD.
Salivary urea nitrogen can also be used as a prognostic indicator in evaluating adequacy of dialysis and monitoring renal
disease status.
A COMPARATIVE STUDY OF HEALTH CARE SEEKING BEHAVIOUR AMONG ADULT MALE AND FEMALE POPULATION RESIDING IN SLUMS OF GUWAHATI CITY
Authors: Sarma Subhra , Hazarika Jhankar , Goswami Kumaril , Ojah Jutika , Chandra Baishya Achyut
Published: September 2023

Primary Health Care is a whole-of-society approach to health
that aims at ensuring the highest possible level of health and
well-being and their equitable distribution by focusing on
people's needs and as early as possible along the continuum
from health promotion and disease prevention to treatment,
rehabilitation and palliative care, and as close as feasible to
.(1) people's everyday environment . In spite of large number of
doctors and para-clinical staffs in urban areas, the existing
health care infrastructure in urban areas is insufcient to meet
the basic health care needs of growing urban poor
population. Health of an individual is inuenced by lot of
factors including social, environmental, genetic and others.
Current views of health and illness recognize health as more
(2) than absence of disease.
FACTORS FAVORING COMPLIANCE TO THE MINIMAL INTER PREGNANCY INTERVAL OF 24 MONTHS AFTER VAGINAL DELIVERY IN YAOUNDÉ
Authors: Ymele Floren Fouelifack , Theodore Tameh , Edwige Djukem , Mosman Ofeh Anyimbi , Fouelifa Loïc Dongmo , Pierre Marie Tebeu
Published: September 2023

Introduction. The inter-pregnancy interval is the period between two consecutive full-term births. The
World Health Organization recommends a minimum inter-pregnancy interval of 24 months between two
live births in order to reduce materno-fetal and perinatal risks. In Cameroon, little is known of the factors favoring compliance to
this interval. Our objective was to determine factors that promote compliance to the minimum inter-pregnancy of 24 months
following vaginal delivery. Methods. We conducted a descriptive cross-sectional study at the Yaoundé Central Hospital from
March 1, 2019 to June 31, 2019. We included every pregnant woman having at least one child who came to consult at the
maternity. A consecutive sampling technique was used. The data were entered and analyzed using Epi Info version 7.2.2.6
software. Our results were expressed as frequency, mean, odds ratio (OR) with its 95% condence interval. P was signicant for
any value strictly lower than 5%. Results. Of 300 participants, 213 (71%) kept the minimum inter-pregnancy of 24 months. The
factors that independently favored this compliance were secondary [AOR (CI): 2.88(1.62-5.10); p<0.001] and higher education
[AOR (CI): 11.91(6.09-23.28); p<0.001], civil servant status [AOR (CI): 4.92(3.13-7.74); p<0.001], modern contraceptive use [AOR
(CI): 3.33(2.36-4.68); p<0.001], and having children with good nutritional status [AOR (CI):14.77(3.31-65.82); p<0.001].
Conclusion. Compliance to the minimum inter-pregnancy of 24 months was inuenced by the mother's educational status,
employment status, use of contraceptive methods, and good nutritional status of the preceding child. It would therefore be
imperative to take this into account during behavior change communication
MYCOLOGICAL PROFILE OF CLINICAL SPECIMENS OF A NEWLY ESTABLISHED TERTIARY CARE CENTRE IN NORTH INDIA – STUDYING THE EPIDEMIOLOGICAL TREND
Authors: Islahi Sana , Singh Sweta , Upadhyay Amrita , Mukherjee Anirudh , Gupta Shefali
Published: September 2023

Background: Fungal infections are emerging as an important cause of morbidity and mortality in critical
patients. For optimal therapy of fungal infections, it is crucial to understand the local etiology as they
exhibit a wide range of diversity based on climatic or geographical factors. Aim of Study: This study was planned with an aim to
study local fungal prole of various clinical specimens received in our Medical College Hospital. Material and Method: This
study is conducted at AIIMS Raebareli. Samples were taken between August 2021 to October 2022. Total 460 samples were
included in the study. Direct microscopy with 10% potassium hydroxide was done to visualize the presence of fungal elements,
and Gram staining was done for any suspected yeast infection. India ink stain was done for cerebrospinal uid. The samples
were inoculated on Sabouraud's Dextrose Agar and kept at 22°C and 37°C. Fungal isolates were identied and documented.
Results: Most common specimen was skin scrapping and isolate was Trichophyton 66.66% followed by Aspergillus, Candida
and Fusarium. Among Trichophyton most common species were T mentagrophytes and T rubrum. Non albicans candida
(58.33%) were common as compared to Candida albicans from pus/aspirates. More fungal infections were found in males
53.7% and in age group of 21-50 (90.5%). Conclusion:It is important to know the local etiology for proper management of fungal
infections. The virulence of many illnesses is greatly inuenced by the fungal isolates, which can now infect both
immunocompetent and immunocompromised people.
KNOWLEDGE AND PRACTICES TOWARDS RABIES, ITS TREATMENT AND PREVENTION AMONG URBAN SLUM DWELLERS RESIDING IN GUWAHATI CITY – A CROSS SECTIONAL STUDY
Authors: Lagashu Sujata , Goswami Kumaril , Hazarika Jhankar , Ojha Jutika , Chandra Baishya Achyut
Published: September 2023

Rabies is one of the neglected tropical diseases (NTD) that
predominantly affects already marginalized, poor and
vulnerable populations. It is transmitted after the bite of a
rabid animal, which are 99% cases of dog bite and is 100 %
fatal if the timely intervention in terms of appropriate
management of wound and Rabies post exposure prophylaxis
is not given to the animal bite victims. Transmission can also
occur if saliva of infected animals comes into direct contact
[1] with mucosa (e.g. eyes or mouth) or fresh skin wounds. As per
WHO estimates, globally, there are 59,000 human deaths due
to dog-mediated rabies. India contributes to one third of the
total global burden due to rabies and two-third of rabies
burden in the South East Asia Region as per the WHO-APCRI
[2] 2004 Survey. In 2015, the world called for action by setting a
goal of “Zero human deaths due to dog-mediated rabies by
[2] 2030”, worldwide. To achieve this target, the most important
strategy should be to continuously and consistently raise
mass awareness campaigns on health seeking behavior
during the animal bites, proper animal bite wound
management, and vaccination strategies among the general
[3] public. Countries like Western Europe, Canada, the US,
Mexico, Japan & Latin America have already eliminated dogmediated Rabies through successful canine rabies
[2] vaccination and one health approach
CLEARING THE AIR: LESSONS FROM GLOBAL AIR POLLUTION POLICIES FOR INDIA'S SUSTAINABLE FUTURE
Authors: C. M Chaitra , M Ananthakrishnan
Published: September 2023

Air pollution poses a pressing challenge to global environmental sustainability and public health, with
India being one of the most affected countries. This review article critically examines the lessons that can
be drawn from international air pollution policies to pave the way for a sustainable future in India. The study delves into the
complexities of air quality management, exploring successful policies implemented across various nations to combat air
pollution. By analyzing the policy frameworks, regulatory strategies, technological innovations, and behavioral changes that
have shown promise in different contexts, this article offers a comprehensive overview of potential pathways for India.
PIRRT (PROLONGED INTERMITTENT RENAL REPLACEMENT THERAPY ) AND SLED ( SUSTAINED LOW EFFICIENCY DIALISIS)
Authors: Tarigan Jerahim
Published: September 2023

Patients with kidney disorders, both acute kidney disorders
(GGA) and chronic kidney disease (CKD), continue to grow.
New patients keep coming to the dialysis unit to get dialysis
services. Often we nd these patients in severe pain with
unstable hemodynamics, making conventional hemodialysis
impossible. For this reason, we are required to learn other
dialysis techniques as a development of the techniques we
have used so far. One of the options is the SLED technique
(Sustained low efciency dialysis). In 1998 Marshal et al at the
University of Arkansas, USA, reported on the SLED (Sustained
Low Efciency Dialysis) technique performed with hybrid
techniques. The rst clinical report on SLED was published in
Kidney International magazine, volume 60, Year 2001.
Marshal et al, managed 37 GgGA patients in critical condition
using the SLED technique. At that time they used a regular
dialysis machine, but slowed down Qd and Qb, and
prolonged tD. This is probably the rst report to suggest that
the SLED technique has an efciency close to that of CRRT.
UNVEILING THE DARK SIDE OF CLINICAL TRIALS
Authors: Rao M.V Raghavendra , Sen Sumana , Pavani G. , Rekha A. , Rangisetty Sindhuja , Anantha Lakshmi G. , Kudari RajKumar. , Kumar Verma Mahendra
Published: September 2023

There is an old saying-“public health is public wealth”.The evolution of drug discovery traverses a long and fascinating
journey.The security of drugs is pivotal because no drug is absolutely safe for all people,in all places,at all times.In the
last few decades,biomedical research has grown tremendously and the use of animals has also increased as a research
model for clinical trials.Clinical trials are crucial for identifying novel disease treatments as well as innovative methods
of disease detection,diagnosis, and risk reduction.Researchers can learn things about what works and doesn't work in
humans through clinical trials that cannot be discovered through laboratory or animal testing.Biomedical research also
assists medical professionals in determining whether a novel treatment's adverse effects are tolerable in comparison to
its potential benefits.There should be strong reasons based on laboratory,animal,and human trials if greater doses are
to be examined. But there would also be a higher chance of adverse outcomes. Management of Drug Disasters among
the human population remains a major therapeutic challenge throughout the world.
MIFEPRISTONE AND MISOPROSTOL VS MISOPROSTOL ALONE IN SECOND TRIMESTER TERMINATION OF PREGNANCY.
Authors: Vani Challa , Pranavi Vamanagunta
Published: September 2023

Introduction: During the last decade, medical methods for second trimester abortion have considerably improved and
become safe and more accessible. The combination of mifepristone and misoprostol is now an established and highly
effective method for second trimester abortion. But where mifepristone is not available or affordable, misoprostol alone
has also been shown to be effective. The objective of this study is to compare the efficacy of mife Objective: pristone with
misoprostol and misoprostol alone for second trimester termination of pregnancy. It is a comparativ Methods: e study
conducted on 60 patients from 13 to 18 weeks of gestation admitted for second trimester termination on legal
indications. Mean induction abortion interval was comparable in both the groups. Of the 30 cases in Results: each group,
nine cases in each Group A and six cases in Group B had incomplete/failed expulsion. Among these 15 cases, only nine
required check curettage for complete evacuation while others received oxytocic's only for completion. The distribution
of these cases was also comparable in both the groups. Only one patient in Group B had complete failure of expulsion
and underwent surgical evacuation. However, the difference in dosage of misoprostol required for complete expulsion
and incidence of side effects were significantly higher in the group B. Mifepristone and misoprosto Conclusions: l
combined is now an established, highly effective and safe method for medical method of second trimester termination.
However, when mifepristone is not available or affordable, misoprostol alone can also be used effectively, although a
higher total dose is needed, and side effects are higher than with the combined regimen
COMPARATIVE STUDY OF CONVENTIONAL AND TOPICAL HEPARIN DRESSING IN LOWER
LIMB DIABETIC ULCERS IN TERTIARY CARE HOSPITAL.
Authors: R. Ekbote G. , Bhat Gautham , Ghuge Kiran
Published: September 2023

Aims And Objectives: Primary: To prospectively compare the healing of lower limb diabetic ulcers in patients with
conventional saline dressing and topical heparin saline dressing. Secondary : To analyze and compare the parameters of
1. hospital stay
2. antibiotic requirements based on culture and sensitivity and
3. analgesia requirement.
Methods: Patients admitted with diabetic ulcer of lower limb are included in the study. By systemic random sampling
and single blinding, those patient will be divided into two groups. (H) group- wound will be dressed with heparinized
saline using 1000 IU/ml sodium aqueous heparin solution USP (heparin) dripped on the ulcer surfaces. (C) groupwound will be dressed with conventional way of normal saline or Povidone Iodine dressing. Analysis of the data is
focused on the outcome measures.
1.Proportion of people whose ulcers have healed completely within the trial period by the end of treatment.
2.Proportion of people whose ulcers have healed completely in the trial period by the end of follow up (trial period).
3.Time to complete healing, or reduced size at end of treatment.
4.Change in area of ulcer within a specific time period (the period of time will be the duration of the study unless
otherwise stated)
Results And Conclusion: Using heparinized saline for dressing the lower limb diabetic ulcers provided peripheral
arterial occlusion ruled out, the wound healing rate is expected to be faster compared to regular saline dressing.
Requirement and change of antibiotics would be less and due to faster recovery, duration of hospital stay would also
significantly reduce.
HYPOGLYCEMIA PRESENTING AS BEHAVIORAL SYMPTOMS
Authors: Sharma Nrupa , Bhambure Narendra
Published: September 2023

An 80 years old male presented with six months history of paroxysmal disorganized behavior. He had hypertension,
diabetes and ischaemic heart disease for the past three decades. Treatment with antipsychotics was not beneficial.
Medical history revealed hypoglycemic dips as the culprit factor.
KUFOR RAKEB SYNDROME
Authors: S Ashok Arya , Gopalkrishna Vishnuvardhan
Published: September 2023

Kufor rakeb syndrome (Parkinson 9 ) is a rare autosomal recessive , juvenile onset disease. It may present as typical
parkinsonism disease or with symptoms not associated such as paraplegia, ataxia supranuclear upgaze palsy. People
with this condition also experience symptoms including anxiety,learning difficulties,visual and auditory hallucinations,
and dementia and depression. World-wide prevalence of KRS is unknown, with only case reports/series being
published.Here we report a case of the same.
THE PRIMITIVE PANIYAN TRIBES IN NILGIRIS WITH REFERENCE TO CULTURES, CONFLICTING SOCIOECONOMIC OUTLOOKS, TRADITIONS, AND DWELLING CONDITIONS - AN ASSESSMENT
Authors: Yoganandham G.
Published: September 2023

The Paniyan tribe in Tamil Nadu, which coexists in remote highlands with Aboriginal and hill tribes, has poor living
conditions, is vulnerable, and is indebted. The Nilgiris region in Tamil Nadu , India, is a well-known tourist attraction and
is home to a diversified population, a mountainous landscape, and numerous Tamil Nadu tribes. The Paniyan, a primitive
Tamil Nadu tribe, face difficulties from newer generations who are adopting varied customs and socioeconomic
advances. They are impacted by industrialization and urbanization and engage in agriculture, hunting, and hunting
skills. They follow odd religions, have negotiated unions, and prefer monogamous partnerships; however some tiny
towns continue observing homosexuality.Paniyan members' relationships include spouses, relatives, and
consanguineous ties. Kinship language is descriptive and divided into statuses. Many Paniyas follow local religions such
as Hinduism. The study paper investigates the Paniyan Tribe's cultural and socioeconomic traditions, focusing on their
level of living, income, and health. The study emphasizes the Paniyan tribal tribe's socioeconomic and cultural presence
in Nilgiri communities. There are 36 scheduled tribal communities in Tamil Nadu, and the rest are unrecognized. The
districts of Selam, Nilgiris, Tharmapuri, and Thiruvannamalai have the highest tribal populations, accounting for 80% of
the total. Their principal source of revenue is physical labour, and they have limited work habits and economic
possibilities. Notwithstanding what was previously stated, the main focus of this study the article is to examine how the
Paniyan Tribe's significant socioeconomic circumstances influence their standard of life, income, and behaviour while
involves seeking health from a variety of theoretical standpoint points. This point of view makes the current issue both
historically and economically relevant, and it also contributes to its growing recognition as a crucial requirement.
PRODUCTION OF FLOWERS CULTIVATION IN ANDRA PRADESH
Authors: Jayalakshmi K.
Published: September 2023

As demand for flowers has gradually increased, floriculture has become an important trade in agriculture in the
commercial sector. Therefore in controlled climatic conditions, commercial flower farming has become a high-tech
operation inside the greenhouse.Floriculture in India,as a high-growth industry,has become significant from the export
point of view.The liberalization of industrial and commercial policies has covered the way for exportation-orienting cut
flowers to grow.It has been grown into the key floriculture centres of Maharashtra,Karnataka,Andhra Pradesh,Haryana,
Tamil Nadu,Rajasthan and West Bengal. On the export front,there has been steady growth in floriculture by 20 percent
last year. In terms of quantity and volume, the domestic flower trade has seen a significant increase in the last decade.
Floriculture in agriculture has been one of the main trades in society both traditionally and seasonally.
“MAXILLARY SINUS FLOOR ELEVATION USING A PRESS-FIT BONE BLOCK IN A CRESTAL
APPROACH FOR DENTAL IMPLANTS-A PROSPECTIVE STUDY.”
Authors: Mangalgi Anand , Ingleshwar Nagesh , T Sowmya , Patil Supriya , Manthale Aishwarya
Published: September 2023

Background :Autogenous bone grafts have been proven to be the gold standard for bone grafting. Although several
techniques for sub-antral bone augmentation have been proposed in the literature, the current trend is towards a less
invasive procedure in sinus lifting and reducing the complications like membrane perforation and sinusitis. Crestal
approach for sinus floor elevation along with an autogenous bone grafting is one such procedure which would give the
desired results with minimum complications. Materials and methods : This study was performed on a total of 10
patients (7 females and 3 males) with the age ranging from 26 to 58 years.The clinical efficacy of maxillary sinus floor
elevation with a crestal approach using a press-fit bone block for dental implants was evaluated in terms of Pre and Postoperative Residual Bone Height,Bone density in Hounsfield Units, Intra-operative and Post-operative Complications.
Results :Study revelaed bone augmentation varied from 9 to 13 mm,with a mean of 10.60 mm. The length of the implants
placed ranged from 8 to 11 mm and the diameter 4.5 mm .Intra-operatively 2 patients had sinus perforation.1 case had
graft resorption and 1 case showed non-union of the graft.None of the cases had any signs of wound dehiscence or donor
site morbidity. Conclusion : In our experience, we believe that there are negligible disadvantages to the crestal
approach for sinus lifting,if performed meticulously with sound knowledge of anatomy of maxillary sinus.
CARIES SUSCEPTIBILITY OF INDIVIDUAL TYPES OF PERMANENT TEETH IN CHILDREN: A
CROSS SECTIONAL STUDY
Authors: Sai Harshitha Sunkavally , Kalla Kamakshi
Published: September 2023

Background: Dental caries is a multifactorial disease, but due to anatomy, differences in time of eruption and other
factors, the susceptibility of individual types of teeth to caries varies. The aim of the study is t Aim: o determine the caries
susceptibility of individual types of permanent teeth This study was conducted by OroGlee Materials and Methods:
Solutions Private Limited, Hyderabad. A total of 5332 subjects aged 8-16 years were examined. Oral examination was
done using an intraoral camera. At 16.39%, molars are the most commonly affected teeth. Premolars, c Results: anines,
and incisors all have a relatively low distribution of caries, with respective caries susceptibility of 1.05%, 0.1%, and 0.7%.
Conclusion: The etiology of caries is multifactorial. However, this study shows that molars are more susceptible to caries
because of their morphology, post-eruptive enamel maturation, and early eruption. Public awareness should be raised
by educating people about proper brushing technique and preventive treatments for caries of molars such as pit and
fissure sealant applications.
A CASE REPORT OF ANNULAR PALMOPLANTAR SYPHILS IN THIS POST COVID 19 ANTIBIOTIC
ERA
Authors: Nikhat Nikhat , Meher Huma
Published: September 2023

Syphilis is an age old major sexually transmitted disease caused by treponema pallidum which can't be forgotten in the
differential diagnosis even in this 21st century of wide antibiotics usage era specially in the post covid 19times.
Conclusion Syphilis shows a good response to penicillin treatment and requires vigilance on the part of practitioners.
We are reporting a High Index of suspicion arises with atypical clinical manifestations, Specific localized atypical, almost
rare form of annular syphilis case in a world of widely antibiotic usage era mostly post covid 19. Henceforth all the
healthcare providers should be consulted by public health professionals who are following up on a patient with a
positive syphilis (or other Sexually Transmitted Infections) case. Dermatologists play an important role in the
recognition and management of syphilis. Timely diagnosis, appropriate management as well as public health
interventions are key in controlling syphilis infection and its spread. Finally, Annular secondary syphilis has a good
response to penicillin treatment. Aim Early diagnosis of syphilis is vital as it is easily treated in its early stages with a
single dose of benzathine penicillin. Timely and effective treatment of early syphilis is important to prevent onward
transmission and progression to tertiary syphilis or the mucocutaneous lesions of secondary syphilis (“syphilids”).
Objectives Syphilis cases should be reported by stage to the local or state health department as soon as possible
Background Syphilis is an infection caused by Treponema pallidum, mainly transmitted by sexual contact [1]. Since
2001, primary and secondary syphilis rates started to rise, with an epidemic resurgence. Syphilis is global prevalence
and incidence remain high in post COVID19. It is divided into primary syphilis, secondary syphilis, tertiary syphilis, and
neurosyphilis. Its florid presentation renders the name “the great imitator” great mimicker “Lues” “THE GREAT POX” [2]
DIGITAL BUREAUCRACY IN MSMES OF TELANGANA TO BE SELF RELIANT
Authors: Raju Kommu , Peri Pinakapani
Published: September 2023

In today's rapidly evolving Telangana business landscape,Micro,Small,and Medium Enterprises (MSMEs) play a crucial
role in fostering economic growth and generating employment opportunities. The Telangana state has been at the
forefront of embracing digital technologies to streamline bureaucratic processes and excel in the ease of doing
business.This paper explores into the concept of "Digital Bureaucracy" and its impact on the self-reliance of MSMEs in
Telangana. The study adopts a mixed-methods approach, merging qualitative interviews with MSME holders and
quantitative analysis of government data. It explores how the implementation of digital solutions in bureaucratic
procedures has influenced the operational efficiency, cost-effectiveness, and overall competitiveness of MSMEs. The
research investigates key areas such as online business registration, licenses and permits acquisition, tax compliance,
and access to financial services. The analysis reveal that the digitalization of bureaucratic processes has led to
substantial improvements in the ease of business operations for MSMEs. Moreover, digital platforms have facilitated
better communication and collaboration between MSMEs and government authorities. The paper also discusses
challenges faced during the transition to digital bureaucracy,including issues related to digital literacy, cybersecurity,
and unequal access to technology.It emphasizes the need for targeted interventions to ensure that all MSMEs can fully
harness the benefits of digitalization. The implications of the study underscore the importance of continued investment
in digital infrastructure, training programs, and policy frameworks that support MSMEs in their journey towards selfreliance. The success of Telangana's initiatives serves as a model for other regions looking to enhance MSME
competitiveness through digital bureaucracy. In conclusion, this paper contributes to the literature on digital
transformation in MSMEs by providing empirical insights into the transformative effects of digital bureaucracy on selfreliance. It offers recommendations for policymakers, business associations, and other stakeholders to foster an
ecosystem conducive to the growth of MSMEs in an increasingly digital world
Diagnostic Overview of Foot-And-Mouth Disease Viruse (FMDV)
Authors: Shimelis Ephrem , Tesfaye Shimels , Tadesse Fanos
Published: September 2023

Foot-and-mouth disease (FMD) is one of the highly contagious diseases of domestic animals. Sensitive, speciﬁc, and quick detection of FMD virus antigens and antibodies is an essential corner stone diagnostic tool at each tier of control strategy. Continued development of molecular and genetic technologies combined with novel analytical techniques will benefit many areas of FMD research and understanding. Genome sequencing provides excellent insight into the evolutionary and epidemiological dynamics of such viruses. The advent of next generation sequencing (NGS) technologies enables evolutionary studies of the entire viral swarm. Sequencing technologies have advanced uses of viral genomic data; which helps to understand the global distribution and Trans-boundary movements of Foot-and-mouth virus disease. Also sequencing information can be used to understand antigenic change within virus strains; therefore, the aim of this review is to assess various diagnostic techniques including conventional and advanced techniques both from agent and host response sides. Among the agent side virus isolation, RT-PCR, antigen ELISA and immune-chromatography strips are commonly used diagnostic tests. Whereas from the host side: infrared thermo gram, antibody ELISA and Virus neutralization are some mentions. Owing to current technological advancement: DNA sequencing and microarray, expressing a luciferase reporter and quantitative proteomics were reviewed. Therefore, potential confirmatory diagnostic test should be in combination with each other.
Evaluation of Improved Malt Barley Varieties in North Shewa Zone, Oromia, Ethiopia
Authors: Negash Geleta , Sefera Gashawu
Published: September 2023

Malting barley is barley that will produce high quality malt. It is a specialty crop for which a premium price is paid by domestic maltters and exporters. Quality requirements for malting barley are reasonably strict and are directly related to processing efficiency and product quality in the malting and brewing industries. Many of the characteristics required are under the control of the producer. Others are determined by weather conditions during the growing and harvesting season. So this trial was conducted on eleven improved malt barley varieties at Fitche Agricultural Research Center for two consecutive years with the objective to identify adaptable, stable, high yielding and its malting potential. The experiment was layout in Randomized Complete Block Design with three replications. Nine agronomic traits data and four major malt quality parameters were evaluated. Analysis of variance detected significant difference among varieties for most observed traits both separated and combined analysis. Observation attained significant differences over years and locations for most traits. The combine ANOVA and the AMMI analysis for grain yield across environments revealed significantly affected by environments that hold 40.42% of the total variation. Genotype and genotype by environmental interaction were significant and accounted 38.11 % and 19.10 % respectively. Principal component 1 and 2 accounted 10. 9 % and 4.19 % of the GEI respectively with a total of 15.09 % variation, the interaction effect of variety by year and variety by location imposed significant effect on most traits. Among evaluated varieties; Singiten and EH1847 had significantly higher mean value of grain yield. Malt quality parameters were conducted in the laboratory of Food Technology and Process Engineering at Holleta Agricultural research center. The mean values of malt quality parameter had malt hot water extract, malt Friability, malt protein content and malt beta-glucan, 78.32%, 58.42%, 10.27% and 492.13mg/L respectively. The results obtained showed that most malt quality had differences among the varieties and some of the results found were within the acceptable limit of EBC (European Brewery Convention) standard even if a single variety may not fulfill all the quality requirements. Based on these findings, the Traveler and the HB1963 varieties fulfill some of the quality parameters that are specified in the EBC range.
Challenges in Celiac Disease Diagnosis
Authors: Hashim Ali Fadhil , Mjeed Maha Sabah
Published: September 2023

Celiac disease (CD) is the most common immune-related gastroenterology which is evoked by the ingestion of gluten peptides found in several types of grains, a condition that rises up both intestinal and extra-intestinal manifestations. Multiple disease may simulate the CD both in the clinical or pathological diagnosis. This issue should be remembered in dealing with suspicious patients having CD. This article focuses on the main pathologies that may pose similarities with CD.
Special Pattern and Distribution Land Suitability for Moringa (Moringa Oleifera) in Kupang District
Authors: Makaborang Marthen , Datta Frans Umbu , Kleden Markus Miten , Mulyantini N.G.A
Published: September 2023

The Kupang Regency in East Nusa Tenggara, Indonesia, experiences 8-9 dry months annually and relies heavily on agricultural and livestock activities, integral to its population. Moringa cultivation for livestock feed is interconnected with these activities. To assess the spatial suitability of moringa plantations, a descriptive study utilized GIS software and overlay methods, incorporating elevation, slope, annual rainfall, temperature data, and land use maps. After excluding forested, residential, and other areas, Kupang Regency's total land area was 288,497 ha. Of this, 114,239 ha were found highly suitable, 138,040 ha moderately suitable, and 36,218 ha unsuitable for moringa cultivation. East Kupang Subdistrict ranked highest in suitable land (16,232 ha), followed by Takari (11,932 ha), Sulamu (9,281 ha), and West Kupang (8,208 ha). Conversely, Fatuleu Tengah (27 ha), Amfoang Tengah (96 ha), and Amfoang Selatan (409 ha) had the least very suitable land. Similarly, Takari (18,279 ha), West Fatuleu (15,784 ha), Fatuleu (14,194 ha), West Amarasi (10,620 ha), and South Amfoang (10,130 ha) excelled in moderately suitable land. In contrast, South Semau (246 ha), East Kupang (434 ha), and Central Kupang (960 ha) had the smallest moderately suitable areas. Unsuitable land for moringa, like South Amfoang (10,270 ha) and Amfoang Tengah (8,932 ha), were prominent. This research aids in identifying optimal locations for moringa cultivation, aligning farming practices with the region's agricultural needs.
The Effect of Smoking Duration Use of Kesambi Leaf Biobriquette-Processed Torrefaction on Cooking Shrinkage and Characteristics Organoleptic Sei's Meat
Authors: S Dethan J. J. , F Bale-Therik J. , S Telupere Franky M. , D Lalel Herianus J.
Published: September 2023

Study this aim for knowledge of the influence of smoking time, use biobriquettes of leaf kesambi torrefied against shrinking, as well as the characteristics of organoleptic colour and texture of sei meat. The study used a random design complete with durations of 60 minutes, 90 minutes, and 120 minutes. Meat weighs 8 kg, is sliced transversely 2-3 cm thick, and is soaked with 16 grams of salt, 2.4 grams of saltpetre, and 2 cloves of white onion. The meat was then hushed up for 2 hours inside a Sokal (a basket made of palm leaves) and closed thermocouple meat entered into meat For measuring internal temperature. Temperature room smoking is guarded between 100°C and 150°C and controlled by four thermocouple sensors. The internal temperature of meat is monitored between 63°C and 77°C. Analysis results show that old curing is influential in shrinking Cook's meat. shrink cooks highest found in the long smoking treatment of 60 minutes (22.96%), and no different with the long curing treatment of 90 minutes. The curing time also affects the colour and texture parameters. Long smoking treatment of 60 minutes No different real with a long smoking treatment of 90 minutes, however different real with a long smoking treatment of 120 minutes. The highest colour parameter value was obtained in the long smoking treatment of 60 minutes (4.50), while the lowest value was obtained in the long smoking treatment of 120 minutes (3.70). The highest colour score was achieved in the long smoking treatment of 60 minutes (4.57), and the lowest score was obtained in the long smoking treatment of 120 minutes (3.33). Long smoking affects shrinkage as well as characteristic organoleptic colour and texture. The treatment that works best is the long smoking time of 60 minutes, which produces shrinkage of 8.6430% as well as colour and texture.
Study of Prevalence and Management of Dental Caries in India: A Systematic Review
Authors: Balwan Wahied Khawar , Saba Neelam
Published: September 2023

Oral cavity is the mirror which reflects general health. Dental caries is widely prevalent globally but the distribution and severity of dental caries varies across countries and regions. Dental caries is a microbial disease of the teeth that results in decalcification of calcified tissue & dissolution of the softened tissue of the teeth. Dental caries has affected the teeth of all nations, irrespective of geographic and bio-cultural differences. Prevalence of dental caries is a pressing health concern affecting at least half of the Indian population.
Stunting Prevention Through Promoting Fish Consumption
Authors: Rindawati Rindawati , Widjajani Roos
Published: September 2023

Implementation of Malang Regent's Regulation Number 33 of 2018 Concerning Stunting Prevention Efforts with the Fish-Eating Socialization Movement is an effort by the Malang District Government through the Fisheries Service to educate the public on the benefits and significance of consuming fish and increase the Fish Consumption Rate in Malang Regency. This study seeks to increase fish consumption in the community, particularly among those suffering from stunting, and to determine the Malang Regency government's strategy for educating the public about the benefits and significance of consuming fish. The researchers employ qualitative research methods. The research was conducted in Sananrejo Village, Turen District, Malang Regency, with data collection techniques including observation, documentation, interviews, and the distribution of questionnaires to pregnant women and breastfeeding mothers participating in the Integrated healthcare center village of Sananrejo Village, Turen District, in order to determine how much they know about the nutrition contained in fish. The findings of this study indicate that a high intake of fish will reduce the incidence of stunting because fish is a rich source of protein and Omega 3, both of which are essential for the growth and development of children. To support the priority program for addressing stunting, you can begin ingesting fish in a variety of fish-based processed diets at an early age.
The Effect of Smoking Durations on pH and Sei Meat Protein
Authors: S Dethan J. J. , F Bale-Therik J. , S Telupere Franky M. , D Lalel Herianus J.
Published: September 2023

The study aims to know the influence of smoking time using bio briquettes leaf kesambi torrefied on pH and meat protein content sei cow. The study used a design complete with a duration of smoking 60 minutes, 90 minutes, and 120 minutes. piece meat weighing 8 kg sliced transverse 2-3 cm thick and soaked in a mixture of 16 grams of salt, 2.4 grams of saltpetre, and 2 cloves of onion white. The meat was then soaked for 2 hours inside a sokal (a basket made of palm leaves) and closed thermocouple meat entered into in meat for measuring internal temperature. Temperature room smoking guarded between 100°C and 150°C, monitored by 4 thermocouple sensors. The internal temperature of meat was monitored between 63°C and 77°C. Analysis variance shows that old curing is influential on the pH and protein content of meat sei cow. The highest protein value was found in the long smoking treatment of 60 minutes (26.13%), different real with the long smoking treatment of 90 minutes. Duration Smoking also affects pH parameters. The pH value of the 60 minutes smoking treatment (7.10) was different real with longer smoking treatments 90 minutes and 120 minutes. Treatment best is the long smoking time of 60 minutes which produces the highest protein content of 26.13% with a pH of 7.10.
Evaluation of the Efficacy of Artemether/Lumefantrine/Doxycycline Combination against Plasmodium berghei in Mice
Authors: Ameja Charity Nnenna , Ogbe Preye David , Ibubeleye Victor Tamunotonye , Georgewill Udeme Owunari
Published: September 2023

Background: Malaria is common in regions like sub-Saharan Africa and South East Asia, where it results in millions of mortalities per year. Resistance to currently available antimalarials further compounds the problem. Drug combination has been demonstrated to be effective in overcoming resistance to antimalarials. This study aimed to assess the efficacy of the combination of Artemether/Lumefantrine (AL) and Doxycycline (DX) against Plasmodium berghei infection in mice. Methods: Thirty Adult Swiss albino mice were inoculated with the chloroquine (CQ)-sensitive P. berghei NK65 strain. The curative test involved oral administration of any of DX, AL, AL/DX, or Chloroquine (CQ) to mice with established infections, while the suppressive test was performed by treating mice shortly after parasite inoculation. Parasitemia levels were monitored using thin smears stained with Giemsa solution. Mean Survival Time (MST) was determined for each group. Results: In the curative test, DX, AL, and AL/DX exhibited parasitemia inhibitions of 81.4%, 94.5%, and 93.2%, respectively, while CQ achieved 93.5% inhibition. MST was significantly extended by DX, AL, and AL/DX treatments compared to negative control (NC). In the suppressive test, parasitemia inhibitions were 79.9%, 96.1%, 95.5%, and 94.9% for DX, AL, AL/DX, and CQ, respectively. The administration of DX, AL, and AL/DX also significantly prolonged MST compared to NC. Conclusion: The study demonstrates that the drug combination, particularly AL/DX, exhibits significant antimalarial effects in both curative and suppressive tests. The combination treatments led to substantial reductions in parasitemia levels and extended mean survival time, indicating their potential as effective antimalarial strategies. These findings highlight the promising role of drug combinations in addressing malaria infections and suggest avenues for further investigation and development of combination therapies.
The Influence of Emotional Intelligence on Learning Motivation for Students at Buddhist College
Authors: Seneru Wistina , Gautama Sidartha Adi , Widiyanto Widiyanto , Andriyaningsih Ayu , Yudhawati Ine
Published: September 2023

The research aims to investigate the influence of emotional intelligence on students' learning motivation. Conducted at Jinarakkhita Buddhist College among second-semester students, this study seeks to establish the significant relationship between emotional intelligence and the level of learning motivation. Utilizing a quantitative approach, the study involves data collection from second-semester students at Jinarakkhita Buddhist College using a research instrument that has undergone validity and reliability testing. Statistical analysis is performed to test hypotheses and assess the association between emotional intelligence and learning motivation. The findings of this research will contribute to a deeper comprehension of the significance of emotional intelligence in shaping students' learning motivation. The implications of this study can provide valuable information for educational institutions to enhance the development of students' emotional intelligence and learning motivation.
Analisa Pemahaman Masyarakat terhadap Ekonomi Syariah
Authors: Nasution Nuriyah , Rahmayati
Published: September 2023

The lack of academic or professional outreach from related institutions, the existence of Islamic Financial Institutions (LKS) does not necessarily play an active role. Not to mention the lack of knowledge of Islamic economics in society, which encourages public perception that the Islamic and Western economic systems are equal. Even though there are many LKS in the area, people's understanding of Islamic economics is still very minimal. This case study was carried out partly because of the concern of the residents of Pangulah Selatan hamlet. The purpose of this research is to increase public awareness and understanding of the fundamental ideas of Islamic economics, support local community economic development, and protect against usury debt (including loan sharks). The author's research methodology is qualitative.
Peluang dan Hambatan Dinas Komunikasi Informatika Statistik dan Persandian dalam mendukung program pembangunan Gubernur Sulawesi Selatan (2018-2023)
Authors: Pangerah Andi Baso Achmad , Cangara Hafied , Arianto
Published: September 2023

The world of global information is experiencing very rapid development, which is marked by the massive and widespread use of information and communication technology by the public and makes it easier for state administrators to serve the community. Enhancement of quality management based on technology, information, and communication is the wrong effort by the government to create transparency and not quite enough to answer maintenance. Matter This is required to increase the ability of the government to provide services to the public. The priority program of the South Sulawesi Provincial Communication Informatics and Encoding Office in an effort to support the vision and mission of the Governor of South Sulawesi in the Regional Medium Term Development Plan (RPJMD) of the South Sulawesi Province is "South Sulawesi that is Innovative, Productive, Competitive, Inclusive, and Characteristic". Program Development and Implementation for e-Government as well as the ‘Baruga Layanan publik’ Development Program Local government must improve the quality of communication related to various programs and activities and ensure that they are accepted, followed, and obeyed by the community. So far, the use of the media is still lacking, especially in the South Sulawesi Provincial Government. Several local and national media outlets are increasingly dominated by leader news, while OPD activities that are directly related to people's lives are not well coordinated and distributed. Especially when it comes to the realization of priority programs.