bluuebunny/crossref_metadata_2025 huggingface dataset:
Trauma-Informed Nutrition Education for Black/African American Perinatal Women with Substance Use Disorder: A Pilot Study
Authors: Rodriguez de Lisenko Norma , Gray Heewon L. , Bohn Joseph
Published: December 2024

Background: Trauma-informed nutrition practices can enhance the physical and mental health of perinatal women of color with substance use disorder (SUD). This pilot study explored the organization's and participants' readiness for a trauma-informed intervention and its effectiveness in improving food resilience among perinatal Black and African American women (BAAW) in a multidisciplinary SUD treatment program. The goal was to establish preliminary research and expand existing literature on trauma-informed nutrition education interventions.
Methods: The study was conducted in three phases: assessing organizational readiness, evaluating participant readiness, and measuring the effectiveness of the intervention. Members of the organization’s leadership and fifteen individuals enrolled in a SUD outpatient program participated. The study used questionnaires to assess the organization's and participants' readiness and six human-food interfaces: family food habits, food-related feelings and thoughts, nourishment, individual food habits, food skills, and personal nutrition. Both qualitative and quantitative data were gathered, and a paired t-test was used to evaluate improvements in these interfaces.
Results: Findings showed that the organization was prepared to adopt the innovative trauma-informed intervention. Participants showed readiness to engage, indicating a positive sign for adapting to change. There was significant improvement in food skills (p < .04), while other food interaction behaviors showed positive trends that were not statistically significant.
Conclusion: This pilot study provided baseline data on the significance of organizational support in adopting an innovative trauma-informed intervention and its effectiveness in promoting behavioral changes in BAAW with SUD. Future research should address the identified limitations and challenges related to implementation.
Effect of Tax Audit on Turnover Tax Compliance among Small and Medium Enterprises in Langata Sub-County, Nairobi, Kenya
Authors: Oringo Leonard Juma , Baimwera PhD Dr. Benard , Kirui PhD Dr. Daniel
Published: December 2024

Purpose: The implementation of turnover tax compliance (TOT) in Kenya was aimed at enhancing revenue collection and improvements in the tax system, the effectiveness of tax administration, and lowering the collection costs in the SME sector. However, over the past decade, the KRA has visibly struggled to implement the tax regime as well as collecting the returns. One of the major shortfalls of the TOT has been its collection due to its dependence on the goodwill among the affected taxpayers. Therefore, the main aim of the study was to establish the effect of tax audit on turnover tax compliance among small and medium enterprises in Langata sub-county, Nairobi, Kenya. The study was anchored on the Economic Deterrence theory.
Methods: The study adopted an explanatory research design. The sample size for this study was 353 derived from 3,061 registered SMEs of the population using Yamane (2012) formulae and the responses by owners/managers of the firms. The study targeted 353 questionnaires with each target firm, 268 respondents managed to fill and return the questionnaires showing a 76% response rate.
Results: The analysis of the hierarchical model found that tax audit has a significant positive effect on TOT compliance (B = 0.373, p = 0.006). In a nutshell, the study found that there is a significant relationship between tax audit and TOT compliance among small and medium enterprises in Langata Sub County, Nairobi, Kenya.
Conclusion: The study recommends conducting frequent tax audits to enhance Turnover tax compliance.
Analisis Dampak Implementasi Norma Penjelasan Dalam Peraturan Perundang-Undangan Terhadap Kepastian dan Efektivitas Penegakan Hukum di Indonesia
Authors: Mery Herlina
Published: December 2024

Norma penjelasan dalam peraturan perundang-undangan di Indonesia dirancang untuk memberikan kejelasan dan panduan dalam implementasi hukum, namun sering kali menghadapi tantangan seperti multitafsir, formulasi yang kurang spesifik, dan rendahnya pemanfaatan oleh penegak hukum. Kondisi ini berdampak negatif pada kepastian hukum, konsistensi putusan pengadilan, dan legitimasi sistem peradilan. Penelitian ini bertujuan untuk mengevaluasi dampak implementasi norma penjelasan terhadap praktik penegakan hukum di Indonesia dan memberikan rekomendasi strategis untuk optimalisasi perannya. Penelitian menggunakan metode yuridis normatif dengan analisis kualitatif terhadap sumber hukum primer, sekunder, dan tersier, serta studi kasus pada putusan pengadilan yang relevan. Hasil penelitian menunjukkan bahwa kelemahan dalam formulasi dan implementasi norma penjelasan sering kali menyebabkan ketidakpastian hukum dan konflik interpretasi. Namun, reformulasi berbasis partisipasi, pelatihan bagi penegak hukum, harmonisasi peraturan, pengawasan implementasi, dan integrasi teknologi terbukti sebagai strategi efektif untuk memperkuat fungsi norma penjelasan dalam mendukung penegakan hukum. Implikasi penelitian ini memberikan kontribusi teoretis dalam pengembangan hukum normatif dan kontribusi praktis bagi pembuat kebijakan dan penegak hukum dalam meningkatkan efektivitas dan legitimasi sistem hukum di Indonesia.
Applications, Risk, Challenges, and Future Prospects of ChatGPT in Electronic Records Management
Authors: Lin Duo , Zou Ruolan
Published: December 2024

The widespread application and rapid development of ChatGPT are disrupting traditional models across industries, bringing revolutionary changes to electronic records management. ChatGPT can be applied in the following scenarios within electronic records management: intelligent classification and archiving, automatic summarization and information extraction, knowledge-based question answering, information retrieval, and semantic analysis with association building. Meanwhile, attention should be given to the following risks and challenges: data privacy and security concerns, legal and ethical issues, and technical sustainability and reliability challenges. Looking forward, the application of ChatGPT in electronic records management is expected to trend toward focusing on core archival areas, innovating record management methods, strengthening regulatory compliance, and enhancing personnel’s data literacy.
Strengthening Nomad as a means of research communication in the Nordic region
Authors: Editors The
Published: December 2024

Ledare / Editorial
The Nordic graduate school in mathematics education – planning for the future
Authors: Grevholm Barbro
Published: December 2024

The ninth seminar for supervisors of doctoral students took place in Tallin in April ...
Omtale av Identitet og forskning
Authors: Gjone Gunnar
Published: December 2024

Wedege, T. (red) (2008). Identitet og forskning: ni essays om at blive matematikdidaktisk forsker. København: Navimat. ISBN 978-87-92397-00-3
Several Nordic research initiatives to follow up the funding of the Nordic Graduate School in Mathematics Education
Authors: Grevholm Barbro
Published: December 2024

Planning for future NoGSME-activities ...
An anthropological approach to a transitional issue – analysis of the autonomy required from mathematics students in the French lycee
Authors: Castela Corine
Published: December 2024

This paper intends to contribute to the process of theoretical networking within the mathematics education research community. Some key elements of the Anthropological Theory of Didactics are recalled and used to deal with the issue of French students’ transitional difficulties in mathematics between Collège (lower secondary school) and Lycée (upper secondary school). The intention is showing how this theoretical framework, in contrast with a theoretical framework of Advanced Mathematical Thinking, provides tools to analyse the changes between these two institutions and thus supports the following assumption: An increasing autonomy as problem solvers as well as mathematics learners is required from the upper secondary school students. This hypothesis led to a clinical investigation on high school students’ homework. This paper addresses the hypothesis by drawing on the case of three high-achieving students.
The role of research in mathematics education reform work
Authors: Editors The
Published: December 2024

Ledare / Editorial
Practical activities in mathematics teaching – mathematics teachers’ knowledge based reasons
Authors: Haara Frode Olav , Smith Kari
Published: December 2024

The current article assumes that mathematics teachers’ understanding of mathematics and professional beliefs are integrated into their professional knowledge. The focus of the article is on teachers’ knowledge based explanations and reasons for choosing practical activities in the teaching of mathematics. Based on interviews of eight mathematics teachers in Norwegian elementary school (where the pupils are 6 to 16 years old), the article analyses and discusses relations between mathematics teachers’ professional knowledge and choice of using practical activities. The findings give grounds for suggesting that both disciplinary and didactical knowledge have an impact on teachers’ choice, and that inexperienced teachers do not have clear knowledge based explanations or reasons for using practical activities at the level of experienced teachers. However, the inexperienced, yet acknowledged teacher will, regardless of high or minimal disciplinary knowledge in mathematics, develop a more thorough and clear opinion on about practical activities as the pedagogical content knowledge deepens through experience.
Future activities in the Nordic graduate school in mathematics education network?
Authors: Grevholm Barbro
Published: December 2024

Another summer school ...
Convergences and influences of discourses in an online professional development course for mathematics teachers
Authors: Erixon Eva-Lena
Published: December 2024

Despite the ever-increasing number of online professional development (OPD) courses, few studies have examined online education for mathematics teachers. This article reports on a case study of discourses in an OPD course for mathematics teachers concerning the convergence and influence of discourses in course seminar discussions and in mathematics teaching in school when course participants are given the task of translating their insights into actual teaching, with a focus on the participants’ discussions of their own and one another’s video-recorded lessons. The analy- sis shows that there is a convergence of discourses in the seminars and in the school context related to a focus on concepts and everyday life connections. However, the study also suggests that there is a risk of students remaining outside in an ”everyday discourse”, in which knowledge of mathematics might be useful, but mathematics is discussed in imprecise and simplified terms.
Finnish entry-level students’ views of teacher knowledge and the characteristics of a good mathematics teacher
Authors: Asikainen Mervi A. , Viholainen Antti , Koponen Mika , Hirvonen Pekka E.
Published: December 2024

This paper reports a study of the views held by Finnish students at the start of their university studies concerning their understanding of the knowledge and characteristics of a good mathematics teacher. A total of 97 students following a basic university course responded to a questionnaire. The results showed that a knowledge of teaching mathematics was more often used to describe the good mathematics teacher than a knowledge of mathematics. According to the students’ views, mathematics teachers need to be able to take the level of understanding of individual students into account in their teaching. Good mathematics teachers were also considered to be skilled in explaining, simplifying and transforming mathematical contents for their students. A good mathematics teacher was often described by the respondents as a patient, clear, inspiring and consistent person. On the other hand, characteristics such as humorous, likeable, empathetic, or fair were seldom used in the students’ responses to describe a good mathematics teacher. Those respondents who planned to become teachers demonstrated a more learner-centred concept of a good mathematics teacher than did those who were aiming at some other subject specialist profession than that of teaching.
Peer assessment of mathematical understanding using comparative judgement
Authors: Jones Ian , Sirl David
Published: December 2024

It is relatively straightforward to assess procedural knowledge and difficult to assess conceptual understanding in mathematics. One reason is that conceptual understanding is better assessed using open-ended test questions that invite an unpredictable variety of responses that are difficult to mark. Recently a technique, called comparative judgement, has been developed that enables the reliable and valid scoring of open-ended tests. We applied this technique to the peer assessment of calculus on a first-year mathematics module. We explored the reliability and criterion validity of the outcomes using psychometric methods and a survey of participants. We report evidence that the assessment activity was reliable and valid, and discuss the strengths and limitations, as well as the practical implications, of our findings.
Seventh-graders 'experiences and wishes about mathematics teaching in Finland
Authors: Pehkonen Erkki
Published: December 2024

The experiences and wishes of about fivehundred Finnish seventh-graders towards mathematics teaching are surveyed using a postal questionnaire. The pupils' responses to three open-ended questions in the questionnaire are classified into six categories: Teacher/teaching, Mathematical topics, Learning control, Pupil, Interaction and working forms, and Resources. Most of the responses (65 - 70 %) are in the first two categories. In addition, a significant percentage (more than 10 %) of the responses are in the class "Pupil" for experiences and in "Interaction and working forms" for wishes. Differences in responses given by boys and girls are discussed and some general suggestions for change in mathematics instruction, based on pupils' experiences and wishes, are put forward.
Dagens gode gerning
Authors: Jensen Stine Grønbæk
Published: December 2024

Hvordan skaber ældre mennesker - der en stor del af livet har været vant til, at det var dem, der skulle tage sig af andre - mening med slægtens hjælp og omsorg for dem? Det er omdrejningspunktet i artiklen, der undersøger, hvordan ældres erfaringer med at modtage hjælp formes af specifikke historiske vilkår indenfor den danske velfærdsstat. Men også gennem en aktiv forhandling af mening, og et vedvarende moralsk arbejde. Jeg argumenterer for, at de ældre til dels håndterer slægtens omsorg ved at vriste sig fri af dominerende dyder knyttet til idealet om aktiv og vellykket aldring – så som selvstændighed. I stedet skaber de mening og handler ud fra dyder som tilhører tidligere perioder af deres liv og som kredser om opofrelse for familien.
HOLISTIC HUMAN CAPITAL DEVELOPMENT: DRIVER OF SUSTAINABLE SUPPLY CHAIN MANAGEMENT IN AFRICA IN THE 4IR ERA
Authors: Maisiri Whisper
Published: December 2024

The future of supply chain management (SCM) has dawned, with global supply chains evolving from traditional linear models to dynamic demand-driven systems. Digitalisation and the advanced technologies of the Fourth Industrial Revolution (4IR) are transforming SCM, which is a crucial specialisation area in industrial engineering, and in which industrial engineers play a significant role in meeting SCM human capital requirements. This discussion paper explores SCM’s holistic human capital development in the 4IR and its potential for driving sustainable SCM in Africa. The study employed a qualitative research approach, using a literature review to examine SCM competency requirements and development, and proposes holistic approaches and strategies for developing SCM competency. In addition, it aims to provoke enquiry and discussion among academics, practitioners, and policymakers to reimagine SCM competency development. The paper could enhance industrial engineers’ specialisation and contributions to SCM.
DEVELOPING AN INDUSTRIAL ENGINEERING CAPABILITIES FRAMEWORK FOR THE ADOPTION OF ENGINEERED WOOD PRODUCTS IN THE SOUTH AFRICAN CONSTRUCTION INDUSTRY
Authors: Hassan Ferdinand , Grobbelaar Schalk
Published: December 2024

The construction industry is embracing sustainable practices to combat environmental degradation and climate change, and engineered wood products (EWPs) offer promise as structural materials for sustainable infrastructure. Despite the benefits of EWPs, challenges such as supply chain integration and market acceptance have limited their use. This paper explores how industrial engineering could facilitate the adoption of EWPs in the South African construction industry, and provides a framework for developing critical industrial engineering capabilities that the South African timber construction sector should possess to integrate EWPs efficiently into construction projects. We used a comprehensive literature review and a curriculum analysis to achieve the study’s objectives. By drawing upon these capabilities, the study identified where industrial engineering as an expertise could drive innovation adoption.
ILLUMINATING A NOVEL ENTERPRISE ENGINEERING METHOD MAKING ARCHITECTURE PRACTICAL – PART TWO
Authors: Auret Marius , Erasmus Louwrence
Published: December 2024

The current work expands on previous practical experience, and presents a practical engineering method to define enterprises. This method employs a series of architecture reference models to create an optimised enterprise free of legacy problems and hidden agendas. Building on the performance and organisation reference models (PRM and ORM), as previously discussed, the method examines the design of the ORM and clarifies the derivation of the business reference model (BRM) from it. By relying on heuristics and self-discovery, this method offers significant potential for optimising organisations. This previously unpublished engineering approach, which has a proven track record, provides a notable, novel, and practical means of designing a fit-for-purpose enterprise architecture.
La transition vers les études postsecondaires : point de vue d’étudiante·s collégien·ne·s et universitaires ayant un TDAH
Authors: Dubuc Majorie , Lagacé-Leblanc Jeanne , Massé Line
Published: December 2024

Chez les étudiant⋅e⋅s ayant un trouble de déficit de l’attention/hyperactivité (TDAH), l’adaptation au contexte d’études postsecondaires comporte des défis supplémentaires par rapport à leurs pairs sans cette condition. Cet article présente les résultats d’une étude qualitative exploratoire visant à décrire l’expérience de la transition chez cette population étudiante au Québec. Des entretiens semi-dirigés ont été menés auprès de 29 étudiant⋅e⋅s ayant un TDAH provenant d’un cégep (n = 10) ou d’une université (n = 19). Les participant⋅e⋅s ont rapporté de nombreux défis liés notamment au nouvel environnement scolaire et aux exigences pédagogiques élevées, ainsi que des facteurs ayant facilité leur adaptation (soutien des proches, acceptation du TDAH). De plus, l’adaptation au contexte collégial semble davantage avoir été une période exigeante et déstabilisante, en comparaison avec le contexte universitaire. Les résultats offrent des cibles d’intervention pour préparer et soutenir ces étudiant⋅e⋅s à la transition.
L’esthétigramme comme outil méthodologique pour la documentation des processus d’apprentissage en recherche qualitative : constats des travaux de recherche disciplinaires
Authors: Lemieux Amélie , Dufour Sarah
Published: December 2024

Dans cet article, les auteures proposent un regard transdisciplinaire sur l’esthétigramme, un outil méthodologique de recherche qui sert aussi de dispositif d’enseignement et d’apprentissage. Leur revue de la littérature fait la lumière sur les apports de l’esthétigramme dans les domaines de l’enseignement des arts visuels, de la littérature, de la littératie numérique et des mathématiques. Cet article vise à montrer le potentiel d’application transversale de l’esthétigramme, à la fois comme outil méthodologique de recherche et comme dispositif d’enseignement dans différentes disciplines.
D’une vague à l’autre… la contribution de l’organisation communautaire en CISSS et en CIUSSS en temps de pandémie
Authors: Deshaies Marie-Hélène , Fournier-Dufour Laurie , Morin Paul , Desgagnés Jean-Yves , Cloutier Suzie
Published: December 2024

Basé sur une recherche qualitative partenariale menée avec le Regroupement québécois des intervenantes et intervenants en CISSS et en CIUSSS (RQIIAC), cet article documente les impacts de la pandémie de COVID-19 sur les pratiques des organisatrices et organisateurs communautaires (OC) du réseau québécois de santé et de services sociaux. L’analyse des entretiens réalisés auprès de 42 OC provenant de 12 établissements révèle d’importantes disparités dans la reconnaissance accordée à cette pratique professionnelle lors de cette crise. Les récits d’expérience indiquent également que certain.e.s ont été en mesure d’apporter une contribution spécifique et originale lors de la pandémie.
Regards d’intervenant·e·s et de gestionnaires sur l’accompagnement des résident·e·s qui
consommaient des substances psychoactives dans les milieux d’hébergement et de soins de
longue durée pour aîné·e·s durant la crise de COVID-19
Authors: Wagner Vincent , Guertin David , Beausoleil Julie , Aubut Valérie , Blanchette-Martin Nadine , Ferland Francine , Huỳnh Christophe , L’espérance Nadia , Flores-Aranda Jorge
Published: December 2024

Cette étude décrit les effets de la pandémie de COVID-19 sur les pratiques
d’accompagnement de l’usage de substances psychoactives dans les établissements
d’hébergement et de soins de longue durée pour personnes âgées au Québec. Nous avons réalisé
48 entrevues individuelles semi-dirigées avec des intervenant·e·s et gestionnaires. Un
ajustement des pratiques s’est observé au fil de la pandémie, incluant des stratégies
d’approvisionnement pouvant s’inscrire dans le champ de la réduction des méfaits. Ces
données soutiennent la nécessité d’offrir une meilleure formation aux équipes sur ces enjeux
de consommation et le développement d’une meilleure collaboration avec les ressources en
dépendance.
¿Por qué justificamos la evasión fiscal? Evidencia empírica a partir de una encuesta factorial en España
Authors: Bartolomé Peral Edurne , Dülmer Hermann , Coromina Lluís
Published: December 2024

Los Estados están obligados a recaudar fondos para financiar bienes y servicios públicos. Al reducir la renta disponible de los contribuyentes, estos impuestos representan cargas que los individuos intentan reducir. El modelo económico estándar explica la evasión fiscal en función de probabilidades de  inspección, riesgo, sanciones, tipos impositivos y renta. Sin embargo, el cumplimiento es mayor que el previsto en este modelo. Para resolver este puzle, la literatura distingue entre cumplimiento coercitivo (modelo económico estándar) y cumplimiento voluntario (modelo basado en legitimidad). Estos y otros elementos se analizan en una encuesta factorial realizada en 2017 a ciudadanos españoles con el objetivo de identificar qué factores influyen en la justificación de la evasión fiscal. Entre los factores situacionales, la renta familiar bruta y el nivel de corrupción del país fueron los que más influyeron en la justificación de la evasión fiscal. Al nivel de los encuestados, el análisis multinivel confirmó que las cohortes de mayor edad, las personas con mayor nivel educativo y los encuestados que creían en principios morales básicos justificaban mucho menos la evasión fiscal. Por lo tanto, nuestro estudio confirma que el cumplimiento de las obligaciones fiscales va más allá del mero cálculo de las ganancias y pérdidas materiales personales. Una implicación práctica es que el Estado debería esforzarse cada vez más por ejercer la transparencia y transmitir eficazmente a los ciudadanos que el uso de los impuestos es justo, equitativo y libre de corrupción.
Sustainable improvement of nutrition quality and biological activity from cassava residue and okara through solid-state fermentation by Pleurotus citrinopileatus mycelium
Authors: Thi Bich Hang Nguyen , Doan Cuong Chi , Khanh Phan Uyen Nguyen , Vu Le Khanh Trang , Bui Thang Duc , Tanaka Munehiro , Vo Minh Van
Published: December 2024

Vietnam's agri-food sector produces 1.64 million tons of byproducts yearly and contributes almost 26% of the country's GDP in 2023. A very small portion of this waste was turned into compost, with the majority being disposed of as waste in the environment. However, there has not been much done in the way of research or technical applications to utilize this residue up to this point. Hence, this study investigated the effect of solid-state fermentation with Pleurotus citrinopileatus mycelia on polysaccharide (PS) and protein contents, antioxidant properties, probiotic growth stimulation, pathogenic inhibition, and bio-physicochemical properties of extracts from culture medium before and after fermentation was investigated. The findings indicated that when cassava (CASS) residue and okara are mixed in a 1:1 ratio, the mycelium develops swiftly uniform, even white, very thick, and high density. The total protein, ash, and PS contents from this fermented mixture were raised by 65.12%, 70%, and 57.24%, respectively. The PS extract inhibited the growth of Escherichia coli and Staphylococcus aureus with sterile ring diameters of 3.47 ± 0.38 and 3.06 ± 0.27 cm, respectively; stimulated the growth of Lactiplantibacillus plantarum with a colony density of 9.34 logCFU/ml after 24 hours of culture; and increased antioxidant capacity with IC50 = 3,287.62 g/ml. Heavy metals content, bacteria, yeasts, and mold levels were all lower than the allowable thresholds as recommended for animal feed purposes. The results show that P. citrinopileatus mycelium can ferment CASS residue and okara to produce a safe and nutritious source of animal feed supplements. This offers a viable approach for enhancing the added value of agricultural residue. Thus, more research is required to assess the financial viability of using fermented substrates produced by oyster mycelium as an additional feed source for animals. Researchers can also concentrate on conducting additional studies on the safety, use, and biological activity of the isolated PS fractions in the functional food sector.
The effect of Citrus reticulata peel extract containing hesperidin on inhibition of SARS-CoV-2 infection based on pseudovirus entry assays
Authors: Septisetyani Endah Puji , Harsan Hayfa Salsabila , Kumara Dennaya , Prasetyaningrum Pekik Wiji , Paramitasari Komang Alit , Cahyani Anisa Devi , Anam Khairul , Kastian Ria Fajarwati , Santoso Adi , Ikawati Muthi , Meiyanto Edy
Published: December 2024

Orange (Citrus reticulata Blanco) peel contains a flavonoid glycoside hesperidin (HSD) as the primary component. Upon enzymatic hydrolysis, HSD forms a flavonoid aglycone derivative, hesperetin (HST). These two flavonoids have been predicted to have in-silico affinities for human Angiotensin Converting Enzyme 2 (hACE2) and SARS-CoV-2 spike, crucial proteins involved in the SARS-CoV-2 infection mechanisms. However, in vitro antiviral testing of orange peel extract, HSD, and HST has not been reported. This study presents for the first time a pseudovirus entry assay approach to test the anti-SARS-CoV-2 effect of HSD, HST, and orange peel extract prepared by hydrodynamic cavitation (HCV). We used a nonvirulent pseudovirus model as an alternative to the original SARS-CoV-2 wild-type virus to target the entry point and enable research to be conducted in a lower biosafety level laboratory (BSL-2). Based on HPLC analysis of 1,000 μg/mL HCV, we observed that our HCV contained HSD at about 4% w/w. Moreover, HSD 1 and 10 μM, HST 10 μM, and HCV 1 μg/mL showed inhibition of pseudovirus entry in 293/hACE2 cells with percentages inhibition 25.92%, 37.40%, 27.32%, and 38.97%, respectively. Despite HCV 1 μg/mL showing about 6 % lower inhibitory activity than HSD 1 μM in pseudovirus entry assay, it holds potential as a supplement or source of raw material for HSD as a SARS-CoV-2 antiviral.
Exploration of the Metabolomic Mechanisms of Postmenopausal Hypertension Induced by Low Estrogen State
Authors: Li Yao , Xin Hui , Lian Zhexun , Zhang Wei
Published: December 2024

Estrogen significantly impacts women’s health, and postmenopausal hypertension is a common issue characterized by blood pressure fluctuations. Current control strategies for this condition are limited in efficacy, necessitating further research into the underlying mechanisms. Although metabolomics has been applied to study various diseases, its use in understanding postmenopausal hypertension is scarce.An ovariectomized rat model was used to simulate postmenopausal conditions. Estrogen levels, blood pressure, and aortic tissue metabolomics were analyzed. Animal models were divided into Sham, OVX, and OVX+E groups. Serum estrogen levels, blood pressure measurements, and aortic tissue metabolomics analyses were performed using radioimmunoassay, UHPLC-Q-TOF, and bioinformatics techniques.The study successfully established a correlation between low estrogen levels and postmenopausal hypertension in rats. Notable differences in blood pressure parameters and aortic tissue metabolites were observed across the experimental groups. Specifically, metabolites that were differentially expressed, particularly L-alpha-aminobutyric acid (L-AABA), showed potential as a biomarker for postmenopausal hypertension, potentially exerting a protective function through macrophage activation and vascular remodeling. Enrichment analysis revealed alterations in sugar metabolism pathways, such as the Warburg effect and glycolysis, indicating their involvement in postmenopausal hypertension.This research provides insights into the metabolic changes associated with postmenopausal hypertension, highlighting the role of AABA and sugar metabolism reprogramming in aortic tissue. The findings suggest a potential link between low estrogen levels, macrophage function, and vascular remodeling in the pathogenesis of postmenopausal hypertension. Further investigations are needed to validate these findings and explore their clinical implications for postmenopausal women.
Genome-wide identification of stable RNA-chromatin interactions
Authors: Wen Xingzhao , Zhong Sheng
Published: December 2024

RNA-chromatin interactions play crucial roles in gene regulation and genome organization, but the interaction landscape remains poorly understood. In this study, we conducted an in-depth analysis of a previously published dataset on RNase-treated in situ mapping of the RNA–genome interactome in human embryonic stem cells. This dataset globally profiles RNase-insensitive RNA-chromatin interactions. Our analysis revealed that RNase treatment selectively preserved long-range RNA-chromatin interactions while removing promiscuous interactions resulting from the local diffusion of nascent transcripts. RNase-insensitive chromatin-associated RNAs (RI-caRNAs) exhibited high sequence conservation and preferentially localized to functional genomic regions, including promoters, transcription factor binding sites, and regions with specific histone modifications. Interestingly, coding and non-coding RNA transcripts showed distinct sensitivities to RNase, with lncRNAs and disease-associated transcripts being enriched among RI-caRNAs. Furthermore, we identified specific caRNA classes associated with individual transcription factors and histone modifications. Altogether, our findings reveal a RNase-inaccessible regulatory RNA-chromatin interactome and provide a resource for understanding RNA-mediated chromatin regulation.
Mütoloogiline tegelane tšokmor udmurtide traditsioonilises maailmavaates
Authors:   Institute of Udmurt Philology, Finno-Ugric Studies and Journalism, Udmurt State University, Russia, Gluhhova Galina
Published: December 2024

Based on linguistic data and ritual practices of the Udmurts, the article explores the etymology of the word chokmor. The analysed material indicates that the term chokmor/chokmorskon is used in the local traditions of both southern (Kiyasovo district) and northern (Kez district) Udmurts during winter and spring-summer ceremonies. The study of the term chokmor in the traditional worldview of the Udmurts allows for the hypothesis that the word is derived from the term chek or cheke, and in this context, in the rituals of commemoration, it serves as a symbol of contact with the otherworldly realm. In the rituals of spring and winter masquerades, it personifies the soul of a deceased ancestor, “appearing” in this world in the form of a masqueraded character.
Estereótipos de gênero no curso de secretariado executivo: uma revisão bibliográfica contemporânea
Authors: Tassi Glauciene Izaltina , Gomes Nicole Schobiner da Costa , Ferreira Thaíssa Mantovani , Ferreira Thiago Spiri
Published: December 2024

Com a predominância feminina no âmbito profissional e acadêmico por quase um século, os estudantes de Secretariado Executivo se deparam com desafios específicos, como o de desmistificar estereótipos historicamente construídos sobre esse ofício e incentivar pessoas do gênero masculino a ingressarem na área. Neste sentido, este estudo busca compreender, com base em estudos na área secretarial, como estudantes e profissionais de Secretariado Executivo enxergam os desafios relacionados ao curso e à atuação no mercado de trabalho. O procedimento metodológico adotado neste estudo trata-se de análise empírica em dados secundários, por se tratar de dados coletados usamos fontes já disponíveis. Como achados da pesquisa, destacam-se a imposição de estereótipos ao Secretariado Executivo, caracterizando a formação acadêmica e o mercado de trabalho como uma relação de gênero, atribuindo a profissão como feminina. A imposição de gênero gera desequilíbrio de oportunidades de trabalho no mercado secretarial para os profissionais que não se enquadram no padrão disseminado, afetando os poucos homens que atuam na área e as mulheres que não se enquadram no estereótipo de beleza.
Compliance trabalhista: auditoria estratégica para mitigação de passivos
Authors: Afonso Marcio , Bofinger Bruna Piegat , Kumm Fernanda Marcia , Souza Leonor Venson de
Published: December 2024

Nos últimos anos, as relações trabalhistas no Brasil passaram por mudanças significativas, marcadas pelas alterações nas leis e no aumento dos litígios entre empregados e empregadores. Este estudo visou criar uma ferramenta baseada em procedimentos de auditoria interna trabalhista para a conformidade e prevenção do passivo trabalhista nas empresas. A metodologia adotada foi descritiva e exploratória, com abordagem qualitativa, combinando análise documental dos relatórios da Justiça do Trabalho de 2020 a 2023 e análise bibliográfica das leis e normas sobre os assuntos mais recorrentes nas causas do passivo trabalhista. O Relatório Anual da Justiça do Trabalho de 2023 indicou um aumento no número de processos trabalhistas em relação ao ano anterior, destacando os principais fatores que geram litígios no país. Com base nas análises realizadas, foram elaborados roteiros de procedimentos destinados a facilitar a implementação nas empresas, com foco na conformidade e na prevenção de passivos trabalhistas. Esses roteiros são particularmente valiosos para empresas com recursos limitados ou que estão em fase inicial, auxiliando-as no cumprimento das exigências legais e, ao mesmo tempo, na redução do risco de ações trabalhistas, o que contribui para a proteção da saúde financeira da organização.
In vitro Study on Fungicide Sensitivity of Alternaria brassicicola for Managing Leaf Blight in Mustard (Brassica juncea)
Authors: Kiran Amita , Mandal Devendra , Kumar Sanjeev
Published: December 2024

Alternaria brassicicola, a phytopathogenic fungus, incites Alternaria leaf blight in mustard, leading to substantial yield and quality losses. This study aimed to investigate the efficacy of seven chemical fungicides against A. brassicicola in vitro. Seven chemical fungicides were assessed at 50, 100, 250, and 500 ppm concentrations using the poisoned food technique and Completely Randomized Design (CRD). Tebuconazole + Trifloxystrobin and Tebuconazole exhibited 100 per cent growth inhibition at 100-500 ppm. Mancozeb + Metalaxyl and Mancozeb demonstrated 100% growth inhibition at 250-500 ppm. Chlorothalanil displayed 83.33% growth inhibition at 500 ppm, while Thiophanate methyl showed the least efficacy (48.00% growth inhibition) at 50 ppm. The findings suggest that Tebuconazole-based fungicides are highly effective against A. brassicicola. Lower concentrations (50-100 ppm) of certain fungicides also exhibited promising results.
Optimizing the Protocol for In vitro Regeneration through Callus in Rice Varieties, viz; Ratnagiri-8, Karjat Shatabdi and Karjat-3
Authors: T. B. Kamble , S. V. Sawardekar , M. G. Palshetkar , S. S. Chavan , K. M. Lonare , A. S. Sarangkar , S. H. Sherkar
Published: December 2024

The investigation entitled “In vitro regeneration studies in rice (Oryza sativa L.)” was carried out in tissue culture laboratory at Plant Biotechnology Centre, College of Agriculture, Dapoli-Ratnagiri (M.H.) in Completely Randomized Design with 3 replications. The aim of the research was to set up the in vitro regeneration protocol in the three rice varieties, viz, Ratnagiri-8, Karjat Shatabdi, Karjat-3 with an objective to investigate suitable callus induction medium and develop an efficient regeneration technique for genetic transformation. Mature seed embryo was used as explant for callus initiation. The callusing ability of the varieties was tested on 12 medium combinations with different concentrations of 2,4-D and NAA, their combinations and one control treatment. Medium combination T2: MS + 2,4-D (2.0 mg/l) + NAA (0.5 mg/l) gave the highest callus induction in Ratnagiri-8 and Karjat Shatabdi with a callus induction frequency of 66.67 % and 53.33 % respectively and callus weight of 0.367 g and 0.290 g respectively. Karjat-3 showed highest callus induction for medium combination T3: MS + 2,4-D (2.0 mg/l) +NAA (1.0 mg/l) with a callus induction frequency of 68.33 % and callus weight of 0.392 g. Embryogenic, soft, friable callus with granular texture and yellowish white colour was obtained from all media combinations in all three varieties. The regeneration ability of the varieties was tested on 15 medium combinations with different concentrations of BAP and Kinetin, their combinations and one control treatment. The shoot and root induction was obtained on same medium. The highest regeneration was observed for T5: MS + BAP (2.5 mg/l) in Ratnagiri-8 and Karjat Shatabdi with a shoot induction frequency of 83.33% and 73.67% respectively and root induction frequency of 76.33% and 64.67% respectively. In Karjat-3, highest regeneration was observed for T6: MS + BAP (3.0 mg/l) with a shoot and root induction frequency of 78.33% and 69.00% respectively.
Photoreduction of CO2 to Formic Acid in Aquatic Phase Using Layer Double Hydroxide (LDH) Catalyst
Authors: Rizkiana Jenny , Auliardi Dzaky , Az Zahra Aghietyas Choirun , Thadeo Francesco , Saputera Wibawa Hendra , Soerawidjaja Tatang Hernas , Devianto Hary
Published: December 2024

The increasing accumulation of CO2, the primary greenhouse gas (GHG), in the Earth's atmosphere has caused significant environmental problems and adverse climate change. Photoreduction offers promising method to convert CO2 into high value chemical compounds, such as formic acid, which can serve as a hydrogen carrier. The process of photoreduction efficiency can be enhanced by using photocatalyst capable of operating across two distinct photosystems each having a different spectrum based on the sensitivity of light. This study aims to investigate the impact of the photocatalyst preparation conditions on the activity of the resulting photocatalyst and identify which is the most effective one on the formic acid production. Photocatalysts based on Layered Double Hydroxide (LDH) composed of zinc and chromium was synthesized, resulting in Zn-Cr LDH, which was subsequently enhanced by incorporating Cu and Cu₂O. The operating temperature varied at 60 ℃ and 100 ℃. The highest yield of formic acid of 21,62 μmol.gcat-1.hr-1 was obtained at a reaction temperature of 100 ℃ using 0.3Cu@Zn-Cr LDH. This photocatalyst shows increased activity when the reaction temperature is increased to 60 ℃ and 100 ℃. In contrast, 0.3Cu2O@Zn-CrLDH showed a decreased activity at the elevated temperatures. This discrepancy attributed to the self-oxidation mechanism of Cu and Cu2O; while the oxidation of 0.3Cu@Zn-CrLDH results in Cu2O which retains photocatalytic activity, the oxidation of 0.3Cu2O@Zn-CrLDH leads to inactive CuO. This study provides valuable insight into the material design and demonstrates the potential of Cu-modified Zn-Cr LDH for sustainable CO2 reduction applications. Copyright © 2024 by Authors, Published by BCREC Publishing Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).
ANÁLISE DA DINÂMICA DE ESTABILIDADE E VAZÕES MÁXIMAS, MÉDIAS E MÍNIMAS DA SUB-BACIA HIDROGRÁFICA DO RIO VERDE-BA
Authors: Martins Cleysla , Gonçalves Mário Mário Jorge de Souza , Puentes Antonio
Published: December 2024

Os estudos hidrológicos são essenciais para melhor uso dos recursos hídricos. Nessa perspectiva, este artigo analisa a dinâmica da estabilidade fluvial e vazões do rio Verde, curso de água principal da sub-bacia hidrográfica do rio Verde (SBHRV), tributária do rio São Francisco, buscando observar mudanças temporais e efeitos da barragem Manoel Novais (Mirorós) na dinâmica fluvial do rio. A metodologia Hidrologia Avançada Experimental (HAE), desenvolvida por Gonçalves (2021), foi utilizada para a avaliação quantitativa das águas, através de dados estatísticos hidrológicos do período de 06/1977 a 12/2021 da Estação fluviométrica 47249000, localizada em Itaguaçu da Bahia. Os gráficos possibilitaram observar variações na dinâmica da estabilidade fluvial, predominando momentos de erosão e assoreamento. Ademais, percebeu-se com a análise temporal significativa redução nas vazões, podendo ter como motivo o impacto da operação e construção da barragem Manoel Novais (Mirorós), bem como outros elementos antrópicos e naturais que constituem a SBHRV.
O ACESSO A ÁGUA NO SEMIÁRIDO: UMA ANÁLISE DA TRANSPOSIÇÃO DO RIO SÃO FRANCISCO
Authors: Oliveira Alana , Jesus Gilda
Published: December 2024

O presente trabalho tem como intenção trazer uma análise de como vem ocorrendo o acesso à água no semiárido, sobretudo tendo como foco a transposição do Rio São Francisco. Teve como principal objetivo a busca por respostas que justifiquem essa escassez de água no semiárido nordestino, e como a água vira palco de mercadoria tanto para o agronegócio, quanto para o Estado, fazendo uma análise da transposição do Rio São Francisco e impactos e conflitos que envolveram essa questão. Para enriquecimento do estudo, se fez uso da metodologia qualitativa de caráter bibliográfico, pois, ela se mostrou de melhor contribuição para a pesquisa, ao fornecer uma base rica e ampla de referências, para se fazer uma investigação aprofundada. Chegou-se à conclusão de que a crise que o semiárido sofre em escassez de água é resultado de disputas capitalistas, de interesses privados e particulares.
BREVE CARACTERIZAÇÃO EM BARRAGENS NO ESTADO DA BAHIA: CATEGORIAS DE RISCO, DANOS POTENCIAIS ASSOCIADOS E USOS
Authors: Oliveira Nilton de Oliveira , Puentes Antonio Puentes Torres , Gonçalves Mário Jorge de Souza Gonçalves , Oliveira Anne Danielle D. de Oliveira , Santos Tiago Ribeiro Santos
Published: December 2024

O presente texto é resultado de diálogos com diferentes segmentos sociais que se preocupam cotidianamente com o expressivo quantitativo de barramentos existentes em municípios baianos a exemplo da porção alta da bacia hidrográfica do rio Paraguaçu onde se encontra o polo agrícola da Chapada Diamantina. O estudo foi norteado no  o Relatório de Segurança de Barragens (RSB) da Agência Nacional de Águas - ANA, ano 2018, e teve como objetivo relacionar os dez municípios da Bahia que mais possuíam barragens naquele ano e, identificar as categorias de riscos, os danos potenciais associados e modos de usos dessas barragens; com os resultados, verificou-se que tanto o critério categoria de risco quanto o dano potencial associado são preocupantes, uma vez que a classificação (alta) predomina em mais de cinquenta por cento (50%) dos empreendimentos cadastrados até o ano (2018). Sobre os modos de usos, a irrigação predomina entre os três municípios baianos que mais possuem barragens cadastradas (Mucugê, Ibicoara e Juazeiro), situação que já se caracteriza como conflituosa em diferentes espaços nesses municípios uma vez que, nos períodos de estiagens prolongadas a oferta de água está se tornando cada vez mais escassa para os pequenos e médios produtores de alimentos.
Der Anwendungsbereich des Ausgleichsanspruchs nach § 255 Abs. 4 AktG – ein unlösbares Puzzle?
Authors: Mock Sebastian
Published: December 2024

Zusammenfasung

Der Ausschluss der Anfechtbarkeit von Kapitalerhöhungsbeschlüssen wegen eines unangemessen niedrigen, auf eine Aktie entfallenden Werts der Einlage nach § 255 Abs. 2 AktG stellt eines der zentralen Reformanliegen des ZuFinG dar. Der Ausgleichsanspruch nach § 255 Abs. 4 AktG soll die sich daraus für die von der Kapitalerhöhung ausgeschlossenen Aktionäre ergebenden Vermögensverminderung ausgleichen; dessen genauer Anwendungsbereich bleibt aber unklar.
Kapitalerhöhungen nach dem ZuFinG — Praxisrelevante Zweifelsfragen
Authors: Hoppe Axel , Knop Johannes
Published: December 2024

Durch das Zukunftsfinanzierungsgesetz wurde u.a. der Rechtsschutz der Bestandsaktionäre bei Kapitalerhöhungen gegen Einlagen völlig neu gefasst. Die Verfasser stellen in ihrem Beitrag dar, welchen Einfluss die Neuerungen auf die Praxis haben und diskutieren zugleich sich aus der Anwendung der Neuregelungen ergebende Zweifelsfragen.
Das neue Recht auf Reparatur – Was ändert sich im digitalen Verbrauchergewährleistungsrecht? — Ein Überblick zu Voraussetzungen und Umfang des Rechts auf Reparatur und zum Pflichtenkreis für Hersteller
Authors: Kapoor Arun , Leucuta David
Published: December 2024

Der Elektroschrott in Europa nimmt stetig zu, während gleichzeitig nach wie vor wenig davon recycelt wird. Und das, obwohl scheinbar ein Großteil der Verbraucher mangelhafte Waren lieber reparieren würde, als neue zu kaufen. In diesem Kontext wurde am 10.7.2024 im Amtsblatt der Europäischen Union die Richtlinie (EU) 2024/1799 über gemeinsame Vorschriften zur Förderung der Reparatur von Waren und zur punktuellen Änderung des Verbraucherschutzrechts veröffentlicht. Dieser Beitrag beleuchtet den Regelungsgehalt der neuen „Recht auf Reparatur“- Richtlinie, wobei ein Hauptaugenmerk darauf liegt, welche Änderungen im digitalen Verbrauchergewährleistungsrecht vorgenommen werden sollen.
Reformbedarf im Gemeinnützigkeitsrecht, Statement
Authors: Weitemeyer Birgit
Published: December 2024

Die Verfasserin würdigt die schwebenden Gesetzesänderungen durch das JStG 2024 und das SteFeG kurz und prägnant. Sie weist auf weiteren Bedarf aus ihrer Sicht zur Reform des Gemeinnützigkeitsrechts hin.
Eigenbedarf: Die sog. Vorratskündigung des Vermieters
Authors: Adam Roman F.
Published: December 2024

In sämtlichen Rechtsgebieten entspricht es allgemeiner Meinung, dass keine Kündigung „auf Vorrat“ erklärt werden darf, d. h. gewartet werden muss, bis ein Grund zur Beendigung von Vertragsverhältnissen tatsächlich vorliegt, wobei vor allem der sog. Vorratskündigung wegen Eigenbedarfs des Vermieters erhebliche Bedeutung zukommt; häufig ist die Bewertung der zugrunde liegenden Umstände, insbesondere im Hinblick auf den Bedarfszeitpunkt und die Eintrittsprognose mit Schwierigkeiten verbunden. Der folgende Beitrag befasst sich zunächst mit verschiedenen Fallgruppen einer unwirksamen Eigenbedarfskündigung, um sich danach ausführlich der sog. Vorratskündigung zu widmen.