bluuebunny/crossref_metadata_2025 huggingface dataset:
Ecoturismo e imaginarios sociales.
Authors: Galimberti Cecilia
Published: January 2024

Los imaginarios sociales y el ecoturismo actualmente registran un papel clave en la transformación sostenible de nuestros entornos, siendo de gran relevancia para detener acciones extractivas y de alta vulnerabilidad socioambiental. Este artículo, a través del caso de la ribera de la ciudad de Rosario y el amplio delta del Paraná en Argentina, se propone indagar críticamente sobre el rol de los imaginarios sociales en torno al desarrollo de políticas y lineamientos turísticos basados en la revalorización del patrimonio y la sostenibilidad territorial. A través de una investigación cualitativa de estudio de caso se busca interpretar los procesos y fenómenos socio-territoriales. El delta del Paraná y ribera central de Rosario consisten en un ámbito representativo de revalorización del patrimonio cultural, edilicio y natural en las últimas décadas, así como, también, sus imaginarios sociales en la actualidad poseen un potencial fundamental para frenar procesos de destrucción de la biodiversidad del delta debido a incendios intencionales extensivos que se han incrementado aceleradamente en los últimos años. En dicho contexto, se considera que el ecoturismo contribuye a incrementar el conocimiento y el vínculo afectivo con el ambiente, posibilitando el desarrollo de prácticas sostenibles e integrales entre la cultura y naturaleza.
Düşey Elektrik Sondajı Verilerinin Genelleştirilmiş Regresyon Sinir Ağları ile Ters Çözümü
Authors: DURDAĞ Doğukan , PEKŞEN Ertan
Published: January 2024

Düşey elektrik sondajı (DES) verilerinin ters çözümü doğrusal olmayan bir problem olması nedeniyle zor bir işlemdir. Bu çalışmada, genelleştirilmiş regresyon sinir ağlarının özdirenç problemine uygulanabilirliği araştırılmıştır. Genelleştirilmiş regresyon sinir ağları (GRNN) ile düşey elektrik sondajı verilerinin ters çözümü test edilmiştir. Sinir ağı düz çözüm ile oluşturulan yapay verilerle eğitilmiştir. Ağ hem eğitim seti içinde bulunmayan diğer yapay veriler ile hem de arazi verisi ile test edilmiştir. Ayrıca GRNN parametresi olan yayılım parametresi de farklı değerler kullanılarak karşılaştırılmıştır. En düşük hata oranını veren yayılım parametresi kullanılmıştır. Yapay veriler 3 tabakalı modellerdir. Arazi verisi ise 4 tabakalı olarak değerlendirilmiştir. GRNN çıktısı yapay verilerde 3 tabakalı model için 3 özdirenç ve 2 tabaka kalınlığı olmak üzere 5 parametredir. Arazi verisinde ise 4 tabakalı bir model için 4 özdirenç ve 3 tabaka kalınlığı olmak üzere 7 parametredir. GRNN ile ters çözüm sonuçları çok düşük hata oranları ile başarılı olmuştur. DES verilerinin kalınlık ve özdirenç kestirimleri için GRNN yöntemi performansı yüksek bir oranda başarılı olmuştur.
Invasive lobular breast carcinoma presenting hepatic carcinomatosis: A case report
Authors: Marques Lays Costa , Barbosa Lizzia Rabelo , Paiva Yasmin Batista de , Guimaraes Isabella Miranda , Salustiano Luciana Ximenes , Gusmão Danilo Araújo
Published: January 2024

Metastatic carcinomatosis to the liver is a pattern of malignant infiltration that tends to provoke liver fibrosis. It is a rare complication of multiple types of solid tumors and often seen in the absence of a discrete tumor mass in the liver. We report the case of a patient who presented the rare diagnosis of metastatic carcinomatosis for liver from breast cancer. A woman at the age of 42 years presented invasive lobular carcinoma, pT3 pN0 M0, positive immunohistochemistry 70% for estrogen receptor and 30% progesterone, HER2 and E-cadherin negative, and Ki67 of 5%. The patient during the fourth year of adjuvant hormone therapy with tamoxifen presented an increase in serum tumor marker (CA 125: 17–130), with no evidence of systemic disease on imaging tests. Due to the slightly cirrhotic contour of the liver on a computed tomography, a liver biopsy was performed for investigation. The early diagnosis of occult and diffuse dissemination to the liver was made by means of a percutaneous liver biopsy showing invasive breast cancer cells, with immunohistochemistry compatible with metastasis of lobular breast carcinoma, positive for hormone receptors, and doubtful for HER-2, with KI67 of 20%. Metastatic carcinomatosis, unlike lesions of discrete liver masses, may not be detectable with imaging tests, and often biopsy or autopsy is needed to confirm the diagnosis. This case highlights a rare and difficult to early diagnosis pattern of hepatic carcinomatosis due to lobular breast carcinoma.
Multidisciplinary treatment after doxorubicin extravasation: Improvement of range of motion in the elbow joint
Authors: Soares Leonardo Ribeiro , Silva Nathállia Alamino , Souza Pedro Vinicyus Novais e , Blumenschein Alexandre Roriz , Lemos Nayara Alves Freitas
Published: January 2024

Introduction: Chemotherapy extravasation is an infrequent complication with challenging consequences for the patient and the care team. Doxorubicin is a chemotherapeutic used in the treatment of breast cancer, being classified as a DNAbinding vesicant agent, and its spillage into the interstitial space can lead to severe tissue damage. The acute condition includes pain, hyperemia, edema, ulceration, and necrosis in the region, evolving with fibrosis, restriction of range of motion (ROM), and other chronic sequelae. Objective: The objective of this study was to describe the multidisciplinary treatment of a case of Doxorubicin extravasation with ROM restriction in the elbow joint. Report: A female, 29 years old, with invasive ductal carcinoma, cT2N1M0, with luminal phenotype B. Neoadjuvant chemotherapy was initiated with AC scheme (Doxorubicin + Cyclophosphamide). There was a suspicion of extravasation in the peripheral access (cubital fossa) during the application of Doxorubicin in the first cycle. Topical treatment with corticosteroids was started, but the patient developed burning sensation, edema, and local hyperemia. In the following days, oral corticosteroids, antibiotics, and dimethylsulfoxide (DMSO) were added, followed by physiotherapy. Despite partial improvement, the patient evolved with skin hyperpigmentation, tissue fibrosis, restriction of elbow extension movement, and arm retraction at 90º, making it difficult to perform domestic and daily activities. After oncological surgical treatment, zetaplasty was performed on the affected arm, with an increase in ROM of about 20º. Subsequently, with the intensification of physiotherapy and pilates sessions, the patient achieved a global improvement of 30º and returned to most daily activities. Thus, we describe a case of Doxorubicin extravasation with chronic sequelae, which was managed by a multidisciplinary team. In this context, physiotherapy played a key role in improving the patient’s ROM and returning to daily activities.
The influence of neoadjuvant chemotherapy response in local recurrence of breast cancer patients undergoing nipple-sparing mastectomy
Authors: Lichtenfels Martina , Malhone Carolina , Miranda Isabela , Falcone Ana Beatriz , Kobe Luiza , Barbosa Fernanda , Vollbrecht Betina , Frasson Antônio Luiz
Published: January 2024

Objective: Our study aimed to examine the influence of response to neoadjuvant chemotherapy (NACT) in local recurrence (LR) of o heterogeneous cohort of breast cancer patients who underwent nipple-sparing mastectomy (NSM) with immediate breast reconstruction. Methodology: We evaluated 101 breast cancer patients undergoing 194 NSM after NACT between January 2004 and December 2020. The data were retrospectively evaluated by the medical chart, and the patient’s follow-up was updated during the appointments. Results: The patient’s median age was 42.9 years. The majority of patients (90.2%) underwent bilateral procedures, and the reasons for the surgery in the contralateral breast were 18.8% diagnosis of high penetrance gene mutation, 4.9% breast cancer in both breasts, 2% atypia, and 74.3% asymmetry/ patient option. Breast reconstruction was performed using silicon prosthetic implants for 98 (97%) patients and with a tissue expander for only 3 (3%) patients. Luminal tumors were more prevalent (43.5%), followed by triple-negative (32.8%), luminal/HER2 (17.8%), and HER2 (5.9%). A complete response to NACT was observed in 23.5% of the patients, and 76.5% presented a partial response. In the mean follow-up of 50 months, 6 (5.9%) patients were diagnosed with LR as the first event, and achieving a partial response to NACT was not correlated to local relapse (p=0.5). When analyzing luminal and triple-negative tumors separately, we observed RPC in 9% of luminal and 36.5% of TN tumors, and all LRs occurred in patients with incomplete response. In luminal tumors with incomplete response to NACT was observed 2.5% of LR versus 9.5% in TN demonstrating an increased LR in triple-negative tumors without RPC to NACT. However, the statistical analysis did not demonstrate significance because of the small sample size. Conclusion: A complete response to NACT is associated with a better prognosis; however, in our mixed cohort, it does not interfere with the chance of developing LR. Further studies with more patients analyzing separately the breast cancer molecular subtypes are needed to verify this preliminary result.
Olaparib in the treatment of leptomeningeal carcinomatosis
Authors: Marques Lays Costa , Lima Ana Claudia Gonçalves , Freitas Nilceana Maya Aires , Abreu Deidimar Cassia Batista , Portela Rafael Gonçalves , Oliveira Felipe Marcio Araujo , Oliveira Leandro Gonçalves
Published: January 2024

Leptomeningeal carcinomatosis (LC) is a complication of breast cancer that carries a poor prognosis. The median overall survival was only 3.8 months. Due to the scarcity of data on therapeutic interventions, patterns of practice vary widely. Preclinical studies have shown that PARP inhibitors penetrate the central nervous system, suggesting a possible role in treatment. We report a case of a patient with BRCA2 and LC mutation who demonstrated an excellent clinical response to Olaparib. A woman had classic lobular carcinoma in the right breast at the age of 50 years. Immunohistochemistry was positive 100% for estrogen receptor and 70% for progesterone, HER2, and E-cadherin negative. Treatment was carried out initially with quadrantectomy and expanded to axillary dissection with 37/39 lymph nodes compromised, pT2 pN3 M0, adjuvant chemotherapy with 4 cycles ACdd and 12 paclitaxel, radiotherapy, and letrozole since March 2019. The genetic panel had a pathogenic mutation in BRCA2. At the age of 53 years, she presented with a headache of strong intensity, peripheral facial paralysis on the right, diplopia, syncope, asthenia, and loss of performance status (ECOG: 3, previous 0). There was negative systemic staging of the occasion and magnetic resonance of the skull with nonspecific white matter enhancement. There was lumbar puncture with positive cerebrospinal fluid for oncotic cytology. He underwent radiotherapy in the total skull with 30 Gy, followed by Olaparib. After 5 months, she presented complete remission of symptoms and negative oncotic cytology of cerebrospinal fluid. Our patient with leptomeningeal metastasis in the context of breast cancer with BRCA2 mutation maintained a complete clinic to Olaparib after 22 months of therapy, her response suggests the efficacy of Olaparib, and its survival far exceeds the reported medians for CL in breast cancer. In conclusion, the present process supports the potential role of PARP inhibitors in the treatment of LC and other CNS metastases of breast cancer in patients with hereditary BRCA mutations.
Hereditary cancer syndromes in patients with second primary breast cancer
Authors: Rodrigues Milena de Freitas , Rocha Ariane Silva da , Gonçalves David Siqueira , Curado Maria Paula , Formiga Maria Nirvana da Cruz
Published: January 2024

Objective: The objective of this study was to evaluate the presence of hereditary cancer syndromes (HCS) in patients with a diagnosis of two primary breast carcinomas and analyze the frequency of pathogenic variants in high- and moderatepenetrance genes. Methodology: This is a retrospective unicentric cohort study on patients with a diagnosis of two primary breast cancers, diagnosed between January 2000 to December 2020, at A.C. Camargo Cancer Center, Brazil. The association between categorical variables was analyzed by the chi-square test or Fisher’s exact test. For survival curves, the Kaplan-Meier method and log-rank test were used to describe the survival curve differences. Results: Medical records of breast cancer patients were reviewed from 2000 to 2020, and a frequency of 600 patients with two primary breast tumors (metachronous or synchronous) was observed. In total, 190 (31.7%) patients performed genetic testing and 35 (5.8%) patients presented a pathogenic or likely-pathogenic germline variant in cancer predisposing genes. Conclusion: Our results revealed a low rate of genetic testing among patients with two primary breast cancers in a cancer center and a frequency of carrier patients lower than expected.
Emotional support for women with breast cancer: New approaches
Authors: Gengo Gisele de Cassia Sales , Makdissi Fabiana Baroni , Sanches Solange Moraes , Santos Silvana Soares
Published: January 2024

Objective: The objective of the Overcoming Project (OS) was to work alongside integrative medicine to increase the perception of personal well-being, quality of life, resilience, and happiness in women diagnosed with breast cancer (CM). Focused on emotional education, it is structured by support groups that promote positive psychology training and coaching sessions. Methodology: Based on prospective methodology focused on expanding emotional awareness for personal growth, it uses the following initial assessments and outcome measures as scales: Hope—Snyder, collaborators (2007) Satisfaction with Life (SWLS) — Diener, collaborators (1985) PANAS — Watson, D., Clark, and collaborators (2011) Achievements — Latham, Gary Flourishing — Diener, E.R. (2010). The work applies 30 concepts of positive psychology distributed in the acronym: O – Objectives, dreams, human being; V – Values, mission, engagement; E – Energy, positive Emotions; R – Roadmap, Planning; C – Comunication, relationships; O – Outlier Minds; M – Making decisions, solve problems; E – Emotional remeaning. The training lasts for 7 months, and 30 tools are worked on in 1h30 online classes, where women express thoughts, feelings, behaviors, and remeanings, creating bonds of friendship and joint development. The classes are followed by individual coaching sessions. The classes and written records of coaching sessions are recorded on a proprietary technological platform, which women have access to for 1 year. Results: Overall average results of the 55 women served: Increase: Hope: 9.45%; Life satisfaction: 8.23%; Achievements: 3.56%; Flourishing: 5.42%; Motivation: 5.45; Positive emotions: 8.3%. Decrease: Negative emotions: -14.3% Conclusion: The work has immense potential to contribute to the emotional health and quality of life of women with CM as emotional awareness causes significant transformations for patients in physical, emotional, social, relationship, and career levels, contributing to healthier and more adherent lifestyle habits to treatment needs, in addition to the ease of scale delivery.
Cohort study on patients with breast cancer treated by neoadjuvant endocrine therapy at hospital nossa Senhora da Conceição, Porto Alegre, RS
Authors: Pedrini José Luiz , Severo Caio Caloca , Veiga Marco Aurélio , Ávila Gustavo Alberto Ozol de , Lichtenfels Martina , Schorr Mário Casales
Published: January 2024

Objective: Our study aimed to analyze the outcomes of a cohort study on patients in Hospital Nossa Senhora da Conceição, Porto Alegre, RS, undergoing neoadjuvant endocrine therapy (NET) for breast cancer. Methodology: A retrospective cohort study was conducted on 28 patients diagnosed with luminal tumors (ER+/HER2–) in a tertiary care center. The patients were treated with NET based on tamoxifen, anastrozole, or letrozole and subsequently operated on or not at clinical discretion. The data on histological classification, treatment time and response, and tumor progression rate were evaluated by the medical chart. Results: The mean patient age was 78 (45–91) years. The most common histological type was ductal (85.7%), followed by lobular (7.1%) and mucinous (7.1%). Low tumor grade (G1) was observed in 14.2% of cases, grade 2 in 71.4%, and grade 3 in 7.1%. Regarding lymph node involvement, 64.2% were NO, 32.1% N1, and 3.6% N2. The mean duration of NET was 22 months, and most patients presented tumor downstaging, with an initial mean tumor size of 3.2 cm and a final mean of 1.8 cm. At the end of the treatment, 60.7% of the patients showed a decrease in tumor size, 28.5% disease stability, and 10.7% disease progression. Of the patients with tumor regression, 21.4% had a complete pathological response to NET. These data are in line with previous literature reporting response rates between 20% and 70% after 3–4 months of NET, which can increase to up to 88% in 12 months. Conclusion: Our cohort corroborates previous literature and supports the effectiveness of NET for the downstaging of luminal breast cancer.
One-STEP TechniqueTM for harvesting fat graft: A new technology to improve the outcome in breast reconstruction
Authors: Gonçalves Bruno Garcia , Zarur Helena Barbosa de Cerqueira , Tumeh Rafael Alves , Montag Eduardo
Published: January 2024

Objective: The authors present a new technique that provides the harvest of the fat graft and conduct its immediate grafting in the breast reconstructed, after the treatment of breast cancer. Methodology: A total of 42 cases were performed by the senior author from April 2019 to December 2022, in patients submitted to breast reconstruction procedures in private hospitals in Goiânia, Goiás, Brazil. All patients have been submitted to surgical treatment of breast cancer in the past, whether by conservative treatment with partial resection and radiotherapy or any kind of mastectomy and implantbased breast reconstruction. Some patients had adjuvant radiotherapy. The Selective Tissue Engineering Photostimulation Technique (One-STEP TechniqueTM) involves using a diode laser with a wavelength of 1,210 nm applied to the subcutaneous tissue from the abdomen, hips, medial thighs, or axillary extension, before harvesting the fat grafts. The fat graft obtained by the One-STEP technique has innovative characteristics; as the laser is specific for the subcutaneous tissue, it reaches its maximum energy at the adipocytes causing them to vibrate, denaturing the connective tissue and releasing the adipocytes and stromal vascular fraction. The fat grafting was carried out immediately after the fat extraction, as an adjunct to improve the quality of the usual results, and no additional processing steps are required. The evaluation of results was performed at 40 and 90 days postoperatively. Results: The technique features make it easier to aspirate the graft and preserve the viability of cells. The authors observed an excellent take of the grafted fat showing great improvement in the skin quality and reduced formation of oil cysts and calcifications. Some patients showed great improvement even in radiated skin. Conclusion: The One-STEP TechniqueTM is an excellent alternative to improve the quality of the fat graft in order to achieve a more aesthetic breast reconstruction.
Special breast tumors: Clinical–epidemiological profile in a reference oncology reference oncology clinic in the capital of Piauí
Authors: Barros Emanuelle de Lima , Machado André Silva , Paranaguá Josie Haydeé Lima Ferreira , Oliveira Marcos Josué Rocha Cabral de , Reis Adaíla Carnib Bemvindo Lima , Meneses Camila Araújo Nery Oliveira , Carvalho Débora Medeiros de , Vieira Sabas Carlos
Published: January 2024

Objective: The objective of this study was to identify the clinical and epidemiological profile of patients diagnosed with special breast tumors, in the period from December 2006 to January 2023, in a reference oncology clinic in the city of Teresina, PI. Methodology: This is an observational, descriptive, quantitative, and retrospective study carried out through data collection from medical records. A total of 982 medical records of female patients with breast cancer were analyzed. Variables such as age, personal and family history of cancer, presence of pathogenic variants in the panel tested, and pharmacological and surgical interventions were analyzed, tabulated, and analyzed descriptively in Microsoft Excel. The study included all the medical records of patients seen in this period, excluding those who did not have breast cancer or whose records did not provide sufficient information. The study was approved by the Research Ethics Committee, advice number 30154720000005209. Results: Of the patients diagnosed with breast cancer, those with special breast tumors represented 1.42% of the total, with a mean age of 56 years. Four types of incident diagnoses were found: papillary carcinoma (35.7%), mucinous (28.6%), metaplastic (21.4%), and medullary (14.2%). Among the clinical characteristics, the most common stage was stage IIA (78.6%), followed by stage IIB (7.1%). Most patients had well-differentiated (50%) or moderately differentiated (21.4%) tumors with negative lymph node involvement. In two of the three cases diagnosed as metaplastic carcinoma, large tumors 9.2 and 15.5 cm in length were observed, with recurrence in both cases. All cases of mucinous carcinoma had the RE+/RP+ pattern. Conclusion: In this study, the cumulative incidence of special breast tumors in women diagnosed with breast cancer in the study population from December 2006 to January 2023 was 1.42%, and of this total, 35.7% were of the carcinoma type papillary carcinoma.
Pengembangan LKPD Berbasis Engineering Design Process (EDP) untuk Meningkatkan Keterampilan Berpikir Kreatif Siswa SMP
Authors: Dila Anisa Ratna , Putra Pramudya Dwi Aristya , Ahmad Nur
Published: January 2024

Tujuan dari penelitian ini untuk mengkaji validitas, efektivitas, dan kepraktisan LKPD Berbasis Engineering Design Process (EDP) untuk meningkatkan keterampilan berpikir kreatif pada siswa SMP. Penelitian ini menggunakan metode pengembangan atau Research and Development (R & D) dengan adaptasi model ADDIE. Lokasi penelitian di SMP Negeri 7 Jember dengan subjek kelas VII D yang berjumlah 36 siswa. Instrumen pengumpulan data meliputi angket validasi, lembar wawancara, lembar tes, lembar keterlaksanaan pembelajaran, dan angket respon siswa. Data yang dianalisis meliputi angket validasi untuk mengukur validitas, lembar keterlaksanaan pembelajaran untuk mengukur kepraktisan, serta angket respon siswa dan lembar tes untuk mengukur keefektifan LKPD yang dikembangkan. Hasil penelitian menunjukkan LKPD yang dikembangkan valid, praktis, dan efektif dengan skor N-Gain sebesar 0,40 dengan adanya peningkatan keterampilan berpikir kreatif pada siswa.
Konsep dan Implementasi Pendidikan Keagamaan Nonformal: Analisis Terhadap Pasal 52 RUU Sisdiknas Vesri Agustus 2022
Authors: Jumaah Jumaah , Mukhlis Mukhlis , Jamaluddin Jamaluddin
Published: January 2024

The purpose of this research is to analyze the concept and implementation of non-formal religious education, with a focus on Article 52 in the Draft Law on the National Education System as of August 2022. The research method employs document text analysis by reading and critically evaluating the provisions of Article 52 in the Draft National Education System Law. Data for this study were collected through documentary research, gathering various documents related to the Draft National Education System Law as of August 2022. Data analysis was conducted by comparing and contrasting the content of Article 52 with the objectives of existing non-formal religious education and within the context of national education. The results of this analysis provide a comprehensive understanding of the concept and potential implementation of non-formal religious education within the proposed legal framework. The findings also illustrate potential implications in the context of national education. This research is expected to contribute to a better understanding of the development of non-formal religious education in the Draft National Education System Law as of August 2022 and provide important insights into changes in religious education in Indonesia.
Membangun Karakter Santun Melalui Kultur Sekolah dalam Kegiatan 5S (Senyum, Sapa, Salam, Sopan, dan Santun)
Authors: Winanda Felia Ayu , Lisdayanti Septina , Kusumaningsih Dewi , Paulina Yanti , Rustinar Eli
Published: January 2024

Penelitian ini mengkaji tentang pembentukan karakter sopan santun melalui budaya sekolah dalam kegiatan 5S. Penelitian ini bertujuan untuk untuk menganalisa secara mendalam bagaimana implementasi kegiatan 5S di sekolah dapat menjadi sarana efektif untuk mengajarkan dan meresapi nilai-nilai karakter santun dalam kehidupan sehari-hari peserta didik,untuk mengetahui cara sekolah membangun karakter santun siswa dalam kegiatan 5S.Kajian ini diteliti menggunakan pendekatan kualitatif dengan metode studi kasus untuk mendeskripsikan kultur sekolah dalam kegiatan 5S (Senyum, Sapa, Salam, Sopan, dan Santun) di SMPN 09 Kota Bengkulu. dikumpulkan melalui melalui observasi, wawancara, dan dokumentasi. Uji keabsahan data menggunakan teknik analisis interaktif Miles & Huberman, kegiatan 5S di SMPN 09 Kota Bengkulu memberikan dampak positif terhadap karakter sopan santun siswa. Beberapa faktor yang menghambat pembentukan karakter sopan santun siswa adalah lingkungan dan keberagaman. Oleh karena itu, pemberian peringatan dan hukuman atau teguran dalam bentuk rambu-rambu dapat diterapkan untuk meminimalisir permasalahan tersebut. Dengan adanya peningkatan karakter, maka kualitas pembelajaran juga dapat meningkat dan menjadi lebih menyenangkan, memotivasi, menginspirasi, dan bermakna. Selain itu, siswa juga terinspirasi untuk menerapkan nilai-nilai karakter santun dalam kehidupan sehari-hari.
Pembinaan Civic Disposition Siswa Melalui Kegiatan Organisasi Pramuka
Authors: Ningsih Ika Juwita , Sumardi Lalu , Sawaludin Sawaludin , Kurniawansyah Edy
Published: January 2024

Organisasi pramuka adalah kegiatan ekstrakurikuler yang dilaksanakan sebagai bagian dari pembinaan karakter di sekolah. Tujuan penelitian ini untuk mengetahui strategi pembinaan civic disposition siswa melalui kegiatan organisasi pramuka serta factor pendukung dan penghambat pembinaan civic disposition siswa melalui kegiatan organisasi pramuka di SMAN 1 Gunungsari. Pendekatan ini menggunakan pendekatan kualitatif dengan jenis penelitian studi kasus. Teknik pengumpulan data menggunakan teknik observasi, wawancara dan dokumentasi. Berdasarkan hasil penelitian bahwa terdapat beberapa civic disposition yang muncul dalam organisasi pramuka antara lain: tanggung jawab individu, disiplin diri, menghormati harkat dan martabat kemanusiaan tiap individu, berpartisipasi dalam urusan kewarganegaraan, dan mengembangkan fungsi demokrasi konstitusional yang sehat. Adapun kegiatan yang di dalamnya mencakup civic disposition pada organisasi pramuka adalah: 1) pionering, 2) Peraturan Baris Berbaris (PBB), 3) Pertolongan Pertama Pada Kecelakaan (P3K), 4) upacara, dan 5) perkemahan. Faktor pendukung pembinaan civic disposition siswa antara lain ketersediaan fasilitas kegiatan organisasi pramuka, dan ketegasan Pembina pramuka. Adapun hambatan yang diterima adalah kurangnya partisipasi siswa.
ANALISIS BUDIDAYA PEMBENIHAN IKAN LELE DI KAWASAN AGRIBISNIS HORTIKULTURA DESA BANGUN SARI
Authors: Tarigan Mhd. Rafi’i Ma’arif , Nasution Alma Salsabila , Saragih Deva Herdina , Yurinanda Salwa , Aqmarina Tadzkia Nasywa , Fadillah Neska
Published: January 2024

Ikan lele merupakan salah satu ikan yang hidup di air tawar yang sudah banyak dibudidayakan oleh masyarakat luas terutama di indonesia. Berkembangnya pembudidayaan ikan lele dikarenakan ikan lele dapat dibudidayakan di lahan yang kecil sekalipun seperti menggunakan terpal dan sumber air yang terbatas. Penelitian ini dilakukan bertujuan untuk mengetahui kendala dan masalah pada kegiatan usaha budidaya pembenihan ikan, sehingga dapat di tentukan strategi guna mengembangkan usaha budidaya ini. Penelitian dilakukan di Jl. Rasmi, Desa Bangun Sari, Kecamatan Tanjung Morawa, Kabupaten Deli Serdang, Kota Medan, Provinsi Sumatera Utara. Adapun metode penelitian yang digunakan dalam kegiatan ini menggunakan metode kulitatif, dimana teknik pengumpulan data menggunakan teknik observasi, wawancara dan dokumentasi yang dilakukan langsung ke desa bangun sari. Adapun hasil data yang diperoleh yaitu terdapat dua jenis ikan yang dibudidayakan pembenihannya yaitu jenis ikan lele pyton dan mutiara. Dari hasil penelitian yang dilakukan ini dapat disimpulkan bahwa penyusunan proses juga harus di perhitungkan dalam sebuah usaha terlebih lagi dalam usaha budidaya perikanan.
ANALISIS USAHA DAN SALURAN PEMASARAN KERUPUK KEPITING BAKAU (Scylla serrata) PRODUKSI MULIA SUMBER REZEKI DI DESA MUARA BENGALON KECAMATAN BENGALON KABUPATEN KUTAI TIMUR
Authors: Baharuddin Dhea Fhernanda B , Helminuddin Helminuddin , Purnamasari Elly
Published: January 2024

Usaha Kerupuk Kepiting ini tidak dapat terlepas dari aspek kelayakan yang meliputi biaya investasi, biaya operasional, produksi dan harga jual. Aspek tersebut sangat mempengaruhi kelayakan usaha. Tujuan penelitian untuk menganalisis kelayakan usaha pengolahan kerupuk kepiting bakau (Scylla serrata) Produksi Mulia Sumber Rezeki di Desa Muara Bengalon Kecamatan Bengalon dengan indikator R/C Ratio, Break Even Point (BEP) dan Payback Period (PP). Penelitian ini dilaksanakan sejak September 2022 sampai dengan April 2023 di Desa Muara Bengalon Kecamatan Bengalon Kabupaten Kutai Timur. Sampel yang digunakan sebanyak 2 responden dengan menggunakan metode pengambilan sampel jenuh (sensus sampling). Hasil penelitian ini menunjukkan pada usaha olahan kerupuk kepiting bakau produksi Mulia Sumber Rezeki di Desa Muara Bengalon Kecamatan Bengalon Kabupaten Kutai Timur berdasarkan analisis kelayakan usaha menguntungkan dan layak untuk dijalankan dengan melihat indikator R/C Ratio, Break Even Point (BEP), Payback Period (PP).
VARIASI SPASIAL KEPADATAN DAN DISTRIBUSI KERANG KIJING (Anodonta woodiana) DI SUNGAI LAHUMBUTI KABUPATEN KONAWE SULAWESI TENGGARA
Authors: Bahtiar Bahtiar , Ernawati Wa , Ramadhan Ramadhan , Purnama Muhammad Fajar
Published: January 2024

Kijing Taiwan merupakan salah satu jenis kerang Asia invasif di beberapa negara yang kepadatan dan distribusinya berbeda-beda di setiap wilayah ekologi. Penelitian ini bertujuan untuk mengetahui variasi kepadatan dan distribusi kerang kijing di Sungai Lahumbuti Konawe Sulawesi Tenggara. Penelitian ini menggunakan metode systematic random sampling dalam proses pengambilan sampel dan purposive sampling untuk penetapan stasiun. Kerang diambil didalam transek kuadrat 1x1 m2 pada 8 stasiun yang dilakukan secara sistematis dalam jarak tertentu antar setiap stasiun.  Kerang terambil di hitung jumlahnya dalam setiap transek dan diukur panjangnya menggunakan jangka sorong ketelitian 0.5 mm. Kualitas perairan diambil bersamaan dengan pengambilan kerang kijing. Data dianalisis dengan formula baku dan kepadatan di setiap tempat diuji dengan Mann Whitney test. Hasil uji Mann Whitney  menunjukkan bahwa kepadatan kerang kijing di stasiun I dan stasiun IV lebih tinggi dibanding stasiun lainnya. Kepadatan terendah ditemukan pada stasiun III, VII dan VIII. Kerang cenderung terdistribusi dari berbagai kelas ukuran di setiap stasiun, namun ukuran kecil terdistribusi pada bagian sungai ke arah hulu, sedangkan ukuran besar relatif terdistribusi pada bagian sungai ke arah muara.  Kerang dominan ditemukan pada ukuran 5,8-7.5 sampai 7,6-9,3 cm. Parameter perairan yang berpengaruh terhadap kepadatan kerang kijing di Sungai Lahumbuti adalah bahan organik perairan.
INKLUSIFITAS SEKTOR PERIKANAN DALAM PEMBANGUNAN BERKELANJUTAN DI PROVINSI SUMATERA SELATAN
Authors: Heirina Anna , Ayub Ayub
Published: January 2024

Sektor perikanan di Provinsi Sumatera Selatan merupakan sektor unggulan. Sektor tersebut selain memberikan sumber bahan pangan yaitu protein hewani, juga memberikan lapangan pekerjaan. Penelitian ini bertujuan untuk melihat peran sektor perikanan dalam struktur perekonomian di Provinsi Sumatera Selatan. Selanjutnya untuk melihat inklusifitas antara Nilai Tukar Petani (NTP) khusus sektor perikanan dilihat hubungannya dengan Produk Domestik Regional Bruto (PDRB) khususnya sektor perikanan, serta nilai inflasi. Metode yang digunakan untuk melihat peran sektor perikanan dalam perekonomian menggunakan analisis deskiptif. Sedangkan, untuk melihat hubungan antara NTP, inflasi, dan PDRB dengan metode statistik yaitu korelasi bivariate pearson. Berdasarkan hasil penelitian, dihasilkan bahwa PDRB sektor perikanan menyumbang 2,90% pada PDRB total Provinsi Sumatera Selatan. Terdapat korelasi yang signifikan pada inflasi dan PDRB sektor perikanan.
Implementation of Patient Safety Program at Hospital Royal Prima Medan in 2021
Authors: Calvin David , Ginting Chrismis Novalinda , Nasution Sri Wahyuni
Published: January 2024

This research aims to know and analyze the implementation of the Patient Safety program and the factors that influence it at the Royal Prima Hospital Medan in 2021. This research is a mixed methods research that is a combination of qualitative and quantitative research. The research informants consisted of 1 person from the hospital health committee, 1 head of the inpatient ward, and 4 implementing nurses in the inpatient ward. The population is all implementing nurses in the inpatient rooms as many as 319 people. the sample was taken using the Taro Yamane formula for as many as 76 people. Data collection techniques through interviews, questionnaires, and documentation. Data analysis methods consist of qualitative analysis with descriptive methods and quantitatively using univariate, bivariate, and multivariate analysis using p multiple linear regression equation. The results of the study that the implementation of the patient safety program at the Royal Prima Hospital Medan in 2021 is quite good; there is an influence of the knowledge, attitude, workload, and supervision of the head of the room on the implementation of the Patient Safety program at the Royal Prima Hospital Medan in 2021.
Understanding the Needs of Institutional Stakeholders in Participatory Cultural Heritage and Social Innovation Projects
Authors: Giglitto Danilo , Ciolfi Luigina , Lockley Eleanor , Cesaroni Francesca
Published: January 2024

This article investigates the current practices and needs of institutional actors operating at the intersection of cultural heritage and social innovation. Through a mixed-methods approach that includes a survey and in-depth interviews, responses have been collected from GLAMs (Galleries, Libraries, Archives, and Museums), social enterprises, public administration, cultural and artistic associations, and educational institutes. A key focus is given to exploring cultural-based participatory practices aimed at engaging disadvantaged communities. The article explores problems and barriers hindering quality engagement, beneficial participation, and impactful outputs, as well as collecting instances of good practice, suggestions, and lessons learnt. The overall goal of this work is to outline the lessons learnt from fields of action to develop guidelines and recommendations for facilitating participatory, collaborative, and inclusive cultural heritage initiatives, including when planning for the use and adoption of digital tools and technologies.
From Crafts to Agency: The Legacy of Colonial Discourses in Exhibiting the Ainu in the Tokyo National Museum and National Museum of Ethnology at Osaka between 1977 and 2017
Authors: Pietersma Edwin
Published: January 2024

The Ainu are indigenous groups of people found in Hokkaido and northeast Honshu, Japan. During the nineteenth century, their land was integrated into the Japanese empire and the people redefined and assimilated. While intended to erase the Ainu as distinct groups, policies and discourses also showed that Ainu communities were not accepted as belonging to the category of ‘Japanese’, with the notions that they lacked Japanese ingenuity and civilization, were stuck in a prehistoric past, and lived in terra nullius. These discourses influenced the formation of museums’ collections in Japan, such as the Tokyo National Museum (TNM) and the National Museum of Ethnology in Osaka (Minpaku). By offering a reading of exhibitions on the Ainu and their accompanying catalogues between 1977 and 2017, this research sheds light on how colonial legacies continue to be shaped and challenged in representing Ainu communities in museums. The TNM seems unable to challenge tropes of this colonial discourse due to their intricate connection with the government, their notion of political neutrality, and their focus on art that tends to exclude the Ainu from the museum. Minpaku, on the other hand, has tried to introduce notions of cultural relativism and centre cooperation with Ainu communities to facilitate best practices.
What Can Museum Anthropology Do in the Twenty-first Century?
Authors: Schorch Philipp
Published: January 2024

This article sets out to tackle the question: ‘what can museum anthropology do in the twenty-first century?’ It does so by focusing on the doing in a double-sense: on what museum anthropology can do, as in affecting, impacting and achieving, as well as on museum anthropology’s own doing, as a particular set of knowledge practices brimming with methodological, epistemological and ontological potentials to be harnessed for its own renewal and for cross-disciplinary fertilization across the academy and beyond the museum itself. The character of the article is programmatic, laying out the program of museum anthropology being developed at LMU Munich, Germany. The article begins by pondering this question explicitly. Then it proceeds by mapping out what has been done, what is being done, and what will be done to address this question at LMU Munich in collaboration with other universities and museums. At the end, the article draws out some of the implications of answering that question for an anthropology not only of and in but through museums, which intervenes in the fields that it studies.
Book Review: Adina Langer (ed.) Storytelling in Museums
Authors: Karbe Ariane
Published: January 2024

The concept of narrative expresses that a representation is not a mere reproduction of facts, but an interpretation of a happening. Within the museum field, this concept has become very popular because two perceptions intersect within the discourse. The first one emphasizes that interpretations are shaped by the perspective of the narrator, which implies the exclusion of other perspectives. The second one sees stories as an effective means of communicating content to an audience. Both ideas are suitable for breaking the exclusivity of museums and giving a voice to marginalized social groups. This close interweaving of political and pedagogical ambitions also characterizes Storytelling in Museums, edited by Adina Langer, which excellently reflects the discourse around the concept of narrative. The eighteen chapters present a broad range of museum and public history projects.
Impacto da Inteligência Artificial na Tomada de Decisões Clínicas: Uma Revisão Abrangente
Authors: Romeiro Edenilze Teles
Published: January 2024

Esta revisão científica oferece uma análise abrangente do impacto da Inteligência Artificial (IA) na tomada de decisões clínicas, explorando os avanços, desafios e implicações associados a essa convergência inovadora entre tecnologia e prática médica. Os resultados revelam avanços significativos, evidenciando a capacidade da IA no diagnóstico preciso, personalização de tratamentos e previsão de desfechos clínicos. No entanto, desafios éticos, regulatórios e práticos surgem, destacando a necessidade de uma abordagem equilibrada. A mudança na dinâmica médico-paciente, os desafios de interpretação clínica e a importância da educação continuada são considerados. As considerações finais enfatizam a necessidade de uma implementação responsável, orientada pela ética, equidade e segurança, enquanto a colaboração interdisciplinar é destacada como crucial para impulsionar pesquisas contínuas e inovação. Este resumo fornece uma visão crítica do estado atual da IA na tomada de decisões clínicas, orientando futuras práticas e pesquisas na busca por uma integração ética e eficaz dessa tecnologia na assistência à saúde.
Isolamento social na pandemia da COVID-19 e a importância da atividade física para a qualidade de vida das crianças.
Authors:   , Lima Sergio Ricardo de
Published: January 2024

A necessidade do isolamento social durante a pandemia da COVID-19 gerou mudanças importantes nas relações humanas, econômicas e políticas, afetando a rotina de todos. Particularmente, as crianças deixaram de ir as escolas, parques e espaços de lazer públicos e privados, os quais permitiam a brincadeira e a interação social. O isolamento social trouxe reflexos profundos na qualidade de vida das crianças, especialmente em função dos impactos causados no hábito alimentar, no sono, na diminuição expressiva do nível de atividade física e no aumento de tempo diante de telas, induzindo a um comportamento sedentário. Tais fatores suscitaram uma preocupação recorrente em relação ao público infantil, que é a obesidade, que diante das restrições impostas pela pandemia contribuem para um balanço energético positivo, ou seja, ganho de peso corporal em razão do maior consumo calórico aliado a redução da prática regular de atividade física. Estratégias para combater os efeitos da quarentena na qualidade de vida tem sido discutida, e uma delas é a manutenção prática da atividade física. Assim, o objetivo do presente trabalho foi realizar uma revisão de literatura sobre as repercussões do isolamento social na pandemia e a importância da atividade física para a qualidade de vida das crianças.
INTERAÇÕES ENTRE O SAGRADO E O PROFANO NO CIBERESPAÇO: AS NOVAS FORMAS DE CONEXÃO ENTRE O SANTUÁRIO DE NOSSA SENHORA DE APARECIDA E OS FIÉIS EM TEMPOS DE PANDEMIA DE COVID-19 NO MUNICÍPIO DE MANAUS-AM
Authors: Carvalho Maria Mayara Rodrigues , Diniz Raphael Fernando
Published: January 2024

Há um ditado popular que diz que futebol, política e religião não se discutem. No entanto, no âmbito da religião, torna-se cada vez mais necessário aprofundar-se em suas questões para expandir o conhecimento acerca da realidade do mundo contemporâneo. Para isso, cumpre, de imediato, reconhecer que o estudo das religiões é um exercício intelectual complexo e que abrange questões históricas e atuais, envolvendo a fé, a crença e a visão particular dos devotos.
No Brasil, existe, por questões culturais, sociais e históricas, a presença de diversas religiões, as quais estão fundamentadas em diferentes crenças. Por muito tempo a Geografia esteve distante do estudo dessas religiões, em suma por muitos intelectuais acreditarem que não possuíam nada em comum com essa ciência. Com o passar do tempo, essa visão acabou sendo abandonada pelas geógrafas e geógrafos que imergiram nos estudos culturais, pois, conforme afirmado por Rosendahl (1995, p. 45): “ambas, geografia e religião, se encontram através da dimensão espacial, uma porque analisa o espaço, a outra porque, como fenômeno cultural, ocorre espacialmente”.
Markov Chains of Molecular Processes of Biochemical Materials
Authors: Orchidea Maria Lecian
Published: January 2024

Biochemical systems are analytically investigated after encoding the properties of the dynamics, which rule the time evolution of the transition properties, using some Markov models, such as the Hierarchical Markov-State Models. The present paper is aimed at analytically writing the (finite) Markov chain originating from the considered Markov models. Within this framework, the interaction with the environment is considered, and the ergodicity of the systems obtained from numerical simulation is controlled and compared with the qualities of the Markov chain. The (von Neumann) conditions to be imposed on the Bloch equations for the biomaterial structures to be described analytically in a consistent way are governed. The formalisms of the ’heat bath’ and that of the control of the numerical errors ensure the good measure-theoretical framework and the ergodicity of the finite chain, respectively. The finite Markov chains are investigated and the analytical expressions are presented, after which the Hierarchical Markov-State-Model provides the time evolution of the transition probabilities in biochemical systems. The notion of heat bath is used to describe the interactions of the biomaterial with the environment and thus to control the uses of the projection operators in the Markovian processes where the appropriate measure is defined; the stochastic equations allow one to obtain the wanted measure from the probability spaces. The cases in which a violation of the Markov property of the process occurs, i.e. in open systems, or dissipative processes are also considered. Furthermore, in complex molecules in biological systems, these features are investigated to be possibly even more dramatic. As far as molecular processes are concerned, this occurrence is associated with the appearance of chaotic effects with certain characteristics of potential surfaces: rather than the technique of isocommittors, the method of projectors in measure spaces is used for the Nakajima-Zwanzig paradigm for the density operator; this latter method complementary compares the time-convolution-less technique. The finite Markov chains are finally proven to be ergodic after the control of the numerical errors which provide the Sinai-Markov partitions to be applied for the analysis of the measure space of the Markov chain, that is, one endowed with a Hilbert measure. The von Neumann conditions are therefore newly demonstrated to be apt to be applied to the Bloch equations for biomaterial structures after the use of the notion of heat bath, from which the measure space arises. The qualities of the Hierarchical Markov-Sate Models which bring the analytical expression of the time evolution of probabilities of biomaterials are therefore newly analytically studied.
Late Presentation of Early-onset Sarcoidosis: A Case Report
Authors: Mutibah Ali Al-essi , Lujain Salah Binkhamis , Samah Mohammed Aljohani , Nora Mohammad Alzahrani
Published: January 2024

Background: Early-onset sarcoidosis is a rare systemic inflammatory granulomatous disease, distinguished by onset before the age of 4 and notably lacking pulmonary involvement. Unfortunately, the condition often shows clinical features similar to juvenile idiopathic arthritis, resulting in the misdiagnosis of numerous patients. This case report delves into the challenges associated with the delayed diagnosis of early-onset sarcoidosis, with a particular focus on the diagnostic methods employed to address this delayed recognition. Case presentation: A 15-year-old girl presented with a history of recurrent fever since infancy, accompanied by rash, arthritis, and joint deformity. Previously misdiagnosed with juvenile idiopathic arthritis, she underwent management with steroids and methotrexate, yielding no improvement. The diagnosis of early-onset sarcoidosis was made during adolescence based on serial examinations, comprehensive laboratory and radiological evaluations, and subsequent histopathology findings. Presently, the patient is receiving treatment with low-dose steroids and biologic therapy (Tocilizumab) and experiencing no disease progression. Conclusion: This case report underscores the importance of considering early-onset sarcoidosis in the differential diagnosis of pediatric patients exhibiting persistent arthritis from an early age. Early detection and treatment are crucial in averting complications and enhancing the overall quality of life.