bluuebunny/crossref_metadata_2025 huggingface dataset:
The schistosomicidal activity of ethanolic extracts from branches, leaves, flowers and fruits of Handroanthus impetiginosus (Mart. ex DC.) Mattos (Bignoniaceae) plant and metabolic profile characterization by UPLC-ESI-QTOF analysis
Authors: Montagnini D. L. , Katchborian-Neto A. , Tahan M. P. M. , Oliveira N. D. , Magalhães L. G. , Januário A. H. , Pauletti P. M. , Cavallari P. S. S. R. , Cunha W. R , Araujo O. P. , Soares M. G. , Ferreira M. S. , Andrade J. V. , Miranda G. S. , Santos M. F. C , Silva M. L. A. e
Published: November 2023

Abstract Schistosomiasis, caused by Schistosoma mansoni Sambon, 1907, is a severe and widely distributed parasitic disease, affecting about 200 million people worldwide. The disease is recognized by elevated mortality rates, especially among those living in areas of poor sanitation. Currently, the chemotherapeutic treatment is solely based on using the praziquantel drug. Therefore, there is a need for the discovery of new medicines for the treatment of this parasitosis. Thus, this work aimed to evaluate the schistosomicidal activity of ethanolic crude extracts from the branches, leaves, flowers, and fruits of Handroanthus impetiginosus (Mart ex DC.) Masttos and characterize its metabolic profile by UPLC-ESI-QTOF analysis. Evaluation of plant extract on S. mansoni was carried out in adult worms in vitro, in which the mortality rate was quantified, and the damages in the tegument of the worms were monitored. All extracts induced changes in the viability of adult males of S. mansoni, causing the death of the parasites, which was directly dependent of the concentration.
Use of organic fertilizers with microbes for improving maize growth, physiology and soil properties
Authors: Flores D. D. Corilla , More López J. M. , Mamani C. M. Caira , Mallma N. E. Saavedra , Cervantes G. M. Manyari , Dominguez J. A. Julcahuanga , Paucarpura V. A. Zarate , Huayhua L. L. Aguirre , García J. V. Nunja , Alejo G. S. Pacovilca , Araujo V. G. Sánchez , Angoma A. Perales , Areche F. Ore
Published: November 2023

Abstract Integrated nutrient management is a promising way to avoid plant nutrient shortages because of the positive relationship between the bioavailability of nutrients and greater economic interest in their application through organic amendments and microbial application. To examine how compost, charcoal, and rhizobium influence maize development, an experiment was set up in a container. In addition to the appropriate amounts of nitrogen, phosphorous, and potassium, the soil in the allotted pots was treated with 50 ml of rhizobium, 5 tonnes of compost, and 2.5 tonnes of biochar before maize seeds were planted. A total of nine treatments (with three replicates each) were arranged in a completely randomized design for this experiment. Various agronomic, chemical, and physiological data were measured and recorded after the crop was harvested 110 days after sowing. The results showed that when biochar, compost, and rhizobium were applied together, the root fresh biomass rose by 43.4%, the root dry biomass increased by 38.3%, and the shoot length increased by 61.7%, compared to the control treatment. Chlorophyll content (41.3% higher), photosynthetic rate (58.5% higher), transpiration rate (64.4% higher), quantum yield (32.6% higher), and stomatal conductivity (25.3% higher) were all significantly improved compared to the control. Soil levels of nitrogen, phosphorus, and potassium were also improved with this treatment compared to the control. The combined use of biochar, compost, and rhizobium was more successful than any of the components used individually in boosting maize yields. Based on the findings of our study, the integration of rhizobium, biochar, and compost within a unified treatment shown a substantial enhancement in both the growth and yield of maize.
Insect galls from the Serra da Bandeira (Barreiras, Western Bahia, Brazil)
Authors: Menezes Jeferson Brito de , Lima Valdeir Pereira , Calado Daniéla Cristina
Published: November 2023

Abstract Understanding the diversity of insect galls is pivotal to the establishment of conservation planning in different Brazilian ecosystems. Here, we (1) characterize the insect galls found on plant host species, (2) identify the gall-inducing insects to the lowest possible taxonomic level, and (3) record the presence of gall-associated fauna. Our study was carried out monthly from August, 2017 to July, 2018 along nine trails in Serra da Bandeira, which is located in an area of Cerrado stricto sensu over a year. We found 48 distinct gall morphotypes, belonging to 12 botanical families. The most morphotypes commonly found were globoid (27.1%), lenticular (27.1%) and cylindrical (25%). The plant organs most affected by galling insects were the leaves (73%), followed by the stem (19%), flower (4%), inflorescence (2%) and fruits (2%). The host botanical families holding the highest number of galls were Fabaceae (26), Malpighiaceae (5) and Anacardiaceae, Combretaceae and Euphorbiaceae (3). We observed that the genus Copaifera Lindl. (Fabaceae) had the greatest diversity of gall morphotypes, harboring 19 morphotypes distributed in three species that occur sympatrically - Copaifera sabulicola J. Costa (Fabaceae), Copaifera depilis Dwyer (Fabaceae) and Copaifera luetzelburgii Harms (Fabaceae). For the first time in Brazil, we recorded the occurrence of galls on flowers of Manihot caerulescens (Euphorbiaceae), on inflorescences of Mimosa acutistipula (Fabaceae) and flower buds of Anacardium humile (Anacardiaceae), which were induced by Cecidomyiidae. Inducers of the order Diptera (Family Cecidomyiidae) were the most abundant, found in 14 morphotypes of galls. Regarding the associated fauna, we found insects primarily belonging the order Hymenoptera, and identified them as parasitoids. The information provided can be used highly by decision makers for conservation programs, as well as in other strategies for the conservation of biological diversity in the Brazilian Cerrado.
Evaluation of genome stability of bone marrow cells of dogs with naturally infected visceral leishmaniasis
Authors: Silva P.M.P. , Pessatto L.R. , Baranoski A. , Oliveira R.J. , Souza A.I.
Published: November 2023

ABSTRACT The aim of this article is to identify and evaluate the genomic stability of visceral leishmaniasis in naturally infected dogs. A total of 32 dogs participated in the study, 24 of which were asymptomatic animals, naturally infected, and 8 uninfected, used as a control group. The comet and micronucleus assay tests were performed on bone marrow cells obtained by means of aspiration puncture. For data analysis, the Shapiro-Wilk test was used to verify the normality of the data, and then the Mann-Whitney and T-tests for the comparison between the infected and control groups. The analysis of samples from naturally infected animals and healthy animals showed that the infection caused by the protozoan responsible for leishmaniasis was not able to induce DNA damage in the cells of the infected animals. In the results obtained through the micronucleus test, an increase in the number of micronuclei were observed in polychromatophilic erythrocytes in the medullary tissue of the infected group, when compared to the control group. As a main contribution, the results expressed in this study, consider that the comet and micronucleus assays are suitable for the biomonitoring of genomic stability in bone marrow cells of naturally infected dogs with visceral leishmaniasis.
Morphological and molecular studies of the nematode parasite Heterakis gallinarum (Heterakidae) infecting the cattle egret Bubulcus ibis (Ardeidae)
Authors: Abdel-Gaber R. , Kamel R. , Maher S. , Fergani Y.A. , Abdel-Gaber R.
Published: November 2023

ABSTRACT Parasites infecting migratory birds all over the world are still under investigation. The identification of parasitic taxa infecting ardeids was done concerning their morphological and morphometric features. A total of 20 Bubulcus ibis (Ardeidae) specimens were collected and investigated for nematode parasites. Only one nematode species, belonging to the Heterakidae family, has been identified, with a prevalence rate of 40% (8/20) among infected egrets. The Heterakis species isolated from the lumen of the ceca of the egret host is morphologically and morphometric compatible with Heterakis gallinarum. Additionally, utilizing the partial small subunit ribosomal RNA (18S rRNA) and mitochondrial cytochrome c oxidase subunit I (COI) genes, maximum parsimony based on the Tamura-Nei model was used to infer the phylogeny of the recovered Heterakis species. The query sequences revealed 99.61% and 97.11% identities for the 18S (MK844591.1) and COI (MF066715.1) genes of the previously mentioned H. gallinarum. In addition to clarifying several morphological features of H. gallinarum, this study also provided new DNA data for this species. The combination of morphological and molecular data could be helpful to other veterinaries in finding a way to treat and control this infection in the cattle egret.
The epidemiological burden of reducing salt intake in Paraguay: A modeling study
Authors: Burgos Rodrigo , Santacruz Ethel , Duarte-Zoilan Derlis , Turnes Catherine , Benitez Gilda , Nilson Eduardo Augusto Fernandes
Published: November 2023

ABSTRACT Objective This study aims to estimate the epidemiological burden of excessive salt intake reduction and achieve the World Health Organization salt reduction target for 2025 in Paraguay, in 2019. Methods We used the Preventable Risk Integrated Model, a comparative risk assessment macro-simulation model, to estimate the averted deaths, disease incidence, and disability-adjusted life years from cardiovascular disease attributable to salt intake in the population of Paraguay for different salt reduction policy scenarios. Results As a result, in Paraguay, excessive salt intake (over 5 g/day) is responsible for approximately 2,656 cardiovascular disease deaths (95% Uncertainty Interval: 1,250-3,765), 4,816 cardiovascular disease cases (95% UI: 2,251-6,947), and 60,529 disability-adjusted life years (95% UI: 27,828-86,258) per year. By reducing salt consumption by 30%, as recommended by the World Health Organization until 2025, approximately 1,188 deaths (95% UI: 520 to 1,820), 2,100 incident cases (95% UI: 923-3,234), and 27,272 disability-adjusted life years (95% UI: 11,999-41,675) from cardiovascular disease could be averted every year. Conclusion In conclusion, the burden of cardiovascular disease attributable to excessive salt intake is significant and salt reduction policies must become a priority in Paraguay.
Assessment of eating habits of preschool children and parent attitudes
Authors: Erdem Feyzanur , Arıca Seçil
Published: November 2023

ABSTRACT Objective The purpose of this study is to investigate preschoolers’ eating behaviors and parents’ attitudes. Methods This descriptive observational study employed a convenience sampling method to investigate the eating behavior of preschool children aged 3-6 years. Data was collected through a Personal and Parent Information Form and the Children’s Eating Behavior Inventory. The study included 206 participants, and the findings provide insights into parental attitudes toward feeding and children’s eating behaviors in 3-6 age group. Results The study sample included 206 parents of children between the ages of 3 and 6, with the majority of children having a normal weight. Parents’ responses to the survey questions revealed significant correlations between children’s weight percentiles and parental education level, maternal body mass index level, and income level. Positive eating behaviors in children were positively correlated with parental age and education level, income level, child age, and child percentile level, while negative eating behaviors were negatively correlated with parental age, educational status, income level, and positively correlated with maternal body mass index level. Gender differences were observed, with male children exhibiting lower mean scores in negative eating behaviors, maternal views and behaviors, child food preparation behavior, and negative meal situations compared to female children. Conclusion We found that parental education level and income level were correlated with children’s positive eating behavior, while they were negatively associated with negative eating behavior. Negative eating behavior and food preparation behavior were lower in boys than in girls.
Antileishmanial and cytotoxic activity of dillapiole n-butyl ether
Authors: BARROS Angela Maria Comapa , PINTO Ana Cristina da Silva , SIMPLICIO Fernanda Guilhon , CHAVES Francisco Célio Maia , SILVA Noam Gadelha da , OLIVEIRA Kelson Mota Teixeira de , LIMA Emersom Silva , FRANCO Antonia Maria Ramos
Published: November 2023

ABSTRACT Among the neglected diseases, American cutaneous leishmaniasis (ACL) still remains highly endemic in some tropical regions. The currently available drugs for treatment are highly toxic, prompting the search for new therapeutic options. The aim of this study was to evaluate the toxic potential of dillapiole n-butyl ether (DBE) against Leishmania amazonensis and L. guyanensis, as well as its toxicity on human peripheral blood mononuclear cells (PBMCs) in vitro. For cell cytotoxicity, concentrations of DBE that ranged from 7.8 to 500 µM were used for 48 and 72 h. For the evaluation of the antileishmanial activity, DBE was tested at concentrations of 0.28 to 18 µM for 24, 48, and 72 h. A value of 36 µM was used for the amastigote assay. The selectivity index (SI) was determined by dividing the CC50/IC50 (macrophages/promastigotes). DBE exhibited a CC50 of 203.9 ± 0.5 µM in 72 h. DBE inhibited promastigote forms with an IC50 of 3.0 µM for both Leishmania species for 72 h. The standard, Pentacarinat®, showed an IC50 of 2.9 µM and 0.3 µM, respectively. The SI of DBE for both species was 67.9 for 72 h. DBE inhibited intracellular forms of L. amazonensis by 65.5% after 48 h. In molecular modeling, DLpOl-F showed two hydrogen bonds (SER418 and 421). DBE demonstrated promising in vitro antileishmanial potential.
Stygocampsomeris manauara (Hymenoptera: Scoliidae: Scoliinae), a new scoliid from the Amazon forest
Authors: GOLFETTI Ivan Fernandes , NOLL Fernando Barbosa
Published: November 2023

ABSTRACT A new species of Amazonian ectoparasitoid wasp, Stygocampsomeris manauara sp. nov., is described almost 50 years after being collected in the region of Manaus, in the central Brazilian Amazon, and stored in the invertebrate collection of the Instituto Nacional de Pesquisas da Amazônia (Brazil). We provide a detailed morphological description and illustrations of the female, a diagnostic comparison of the new species with Stygocampsomeris servillei Lepeletier, and a key for the identification of females of Stygocampsomeris.
NEIKO-ERÓTICA: A LITERATURA ERÓTICA CONTEMPORÂNEA À LUZ DA PSICANÁLISE FREUDIANA
Authors: Teodoro Elizabeth Fátima , Chaves Wilson Camilo
Published: November 2023

RESUMO: Este texto objetiva apresentar uma leitura da literatura erótica contemporânea a partir da teoria psicanalítica de Sigmund Freud. Percorrendo a história da escrita feminina e da literatura erótica, verifica-se o surgimento da chamada literatura erótica contemporânea. Entre as características desse gênero, destaca-se o cenário das tramas eróticas que torna central um eixo sombrio no qual gravita a sexualidade das personagens que, à luz da teoria freudiana, pode ser lida como um caráter disruptivo, característica fundamental das relações amorosas. Nesse viés, para que a erótica se valha como tal, torna-se necessária a presença de um traço discordante que nomeamos de neiko-erótico.
Validation of the brazilian version of the Penn State College of Medicine Professionalism Questionnaire
Authors: Valadão Patrícia Aparecida Silva , Lins-Kusterer Liliane , Silva Mary Gomes , Aguiar Carolina Villa Nova , Mendonça Dilton Rodrigues , Menezes Marta Silva
Published: November 2023

Abstract Introduction: Assessing professionalism represents a challenge for medical educators given the nature of its construct, which comprises diverse values, beliefs, and principles. Understanding this psychological phenomenon is fundamental for reaching the goals in medical education. Objective: This study aimed to translate into Brazilian Portuguese and to validate the Penn State College of Medicine Professionalism Questionnaire. Method: The questionnaire was translated, and cross-culturally adapted into Brazilian Portuguese using data from 249 medical students. An exploratory factor analysis was conducted, using a polychoric matrix and the Robust Diagonally Weighted Least Squares method of extraction. The following model adequacy indexes and criteria were used: Root Mean Square Error of Approximation (RMSEA) adjustment indexes <0.08, Comparative Fit Index (CFI) and Tucker-Lewis Index (TLI) >0.90. Result: The exploratory factor analysis obtained a KMO = 0.920, and a significant Bartlett’s test of sphericity (2719.0, gl = 630; P <0.001). The parallel analysis yielded a three-factor solution, which showed adequate levels of reliability: Professional-Patient Relationship, Professional Development and Ethical Commitment. The three-factor solution was the best one found to represent the data. Conclusion: The questionnaire evidenced good psychometric properties and appropriateness to evaluate medical students’ professionalism, contributing to reach more desirable ethical standards in medical education.
Monitoria acadêmica: uma formação docente para discentes
Authors: Souza João Pedro Nunes de , Oliveira Silvia de
Published: November 2023

Resumo Introdução: A monitoria acadêmica é um processo de formação e introdução à docência que é prevista nas Diretrizes Curriculares Nacionais de 2014 e tem o potencial de conferir maior competência à área de educação em saúde a qual é valorizada pelo Sistema de Acreditação de Escolas Médicas como um indicador internacional de qualidade. Objetivo: O estudo buscou identificar as principais potencialidades e desafios da monitoria acadêmica na formação médica. Método: Trata-se de um estudo observacional descritivo de caráter transversal realizado com 11 estudantes de Medicina, por meio de entrevistas semiestruturadas e com análise de dados feita a partir de uma abordagem qualitativa do tipo textual-discursiva. Resultado: Os códigos foram reunidos em quatro categorias: 1. motivações para participação, 2. desafios enfrentados, 3. aprendizados desenvolvidos e 4. carreira docente. A principal motivação foi currículo, seguido de interesse em aprender conteúdo. Os maiores desafios foram o desenvolvimento da responsabilidade e a explicação do conteúdo. Dentre os aprendizados, habilidades didáticas, aprendizagem significativa e metodologias de ensino foram as mais prevalentes. Em termos de carreira, a monitoria ao menos apresentou a docência como possibilidade para além da prática médica assistencial, e os aspectos ser facilitador, ter habilidades interpessoais e preocupar-se com o aluno constituíram a tríade - na visão dos monitores - de um “bom professor”. Conclusão: A monitoria acadêmica é uma prática didático-pedagógica capaz de estimular o interesse e a profissionalização da carreira docente. Além disso, deve ser incentivada pelas políticas públicas e institucionais com o objetivo de qualificar futuros médicos para que possam atuar como educadores em e na saúde.
Cross-Cultural Adaptation and Validation of the Emotional Intelligence Self-Perception Questionnaire
Authors: Teques Andreia Patrícia de Sousa Pereira , Cavalcanti Helton Alexsandro Firmino , Barbosa Leopoldo Nelson Fernandes , Teques Pedro Humberto Araújo
Published: November 2023

Abstract The assessment of emotional intelligence is limited by the lack of psychometrically valid instruments. The present study aimed at cross-culturally adapting and validating the Emotional Intelligence Self-perception Questionnaire (EIQ-SP) in samples of Brazilian and Portuguese university students. Within this scope, in a sample of 1,074 students, reliability, construct-related validity, and criterion-related validity were analyzed. Additionally, metric invariance between the two samples and between genders was assessed. EIQ-SP showed appropriate psychometric qualities in its validation for use in Brazil, maintaining Mayer and Salovey’s four-branch model. With a short application time, simple and objective language, its small number of questions makes it an attractive and valuable instrument to investigate Emotional Intelligence.
AVALIAÇÃO EXTERNA E AVALIAÇÃO INSTITUCIONAL: EMBATES E DIÁLOGOS PARA CONSTRUÇÃO DA QUALIDADE SOCIAL
Authors: Sordi Mara Regina Lemes de , Oliveira Sara Badra de , Almeida Luana Costa
Published: November 2023

RESUMO O presente artigo estabelece um diálogo entre os processos de avaliação externa de larga escala e de avaliação institucional participativa, a partir da análise de quatro modelos de avaliação à luz de categorias consideradas importantes dentro da lógica emancipatória vista como contraposta à lógica mercadológica. Com isso, propõe-se uma forma de análise dos modelos avaliativos que, longe de ser norteada pelas díades quantitativo/qualitativo, externo/interno, filie-se à lógica emancipatória. Por fim, discute-se a importância de eleger indicadores de qualidade coerentes à epistemologia decolonial, construindo rotas de fuga a uma leitura de qualidade educacional ainda marcada pelo imperialismo cultural e econômico. Trata-se, pois, de um trabalho contra regulatório que subsidiará a reflexão e ação dos profissionais da educação, devidamente articuladas com as forças vivas da escola e expressas num pacto de qualidade negociado, responsavelmente administrado em nome de um futuro comprometido com a justiça social.
Controlando o Protesto: Repertório, Estratégias e Aprendizagem no Policiamento do Ciclo de Protestos de 2013-2014
Authors: Fernandes Eduardo Georjão , Silva Marcelo Kunrath
Published: November 2023

Resumo Entre 2013 e 2014, com o ápice em junho de 2013, Porto Alegre foi palco de um conjunto de protestos, caracterizados pela heterogeneidade de reivindicações, de grupos mobilizados e de interações táticas entre policiais e manifestantes. O objetivo deste artigo é analisar, com base nesse caso, como o repertório e as estratégias de policiamento de protestos mantêm-se ou transformam-se durante um ciclo de protestos. A investigação foi realizada por meio da análise de eventos de protesto em jornais e de entrevistas com agentes policiais. Sob a perspectiva relacional da teoria do confronto político, foram identificados quatro mecanismos que conformam o processo de aprendizagem vivenciado pelas forças policiais durante o ciclo: problematização do repertório de policiamento; identificação de alternativas; experimentação tática; incorporação das mudanças. As transformações resultaram na ampliação do uso de táticas policiais de monitoramento, combinada à estratégia de antecipação à ação dos manifestantes.
Intensive fish farming: changes in water quality and relationship with zooplankton community
Authors: Storck Tamiris Rosso , Sippert Leticia Raquel , Seben Débora , Lazarotto Dinei Vitor , Helfenstein Júlia , Luz Jheniffer dos Santos da , Cerezer Felipe Osmari , Schneider Silvana Isabel , Wastowski Arci Dirceu , Clasen Barbara , Golombieski Jaqueline Ineu
Published: November 2023

Abstract Aim This study aimed to evaluate the interference of intensive fish farming in the physicochemical variables of water and in the zooplankton community from a tilapia (Oreochromis niloticus Linnaeus, 1758) pond in southern Brazil. In addition, it was verified whether the analyzed zooplankton groups could be bioindicators of changes in the quality of pond water. Methods The water and zooplankton sample collections were carried out monthly in different places of the pond: at the water supply site (affluent), in the middle of the pond and at the water outlet site (effluent). Analyzes related to nitrogen series (total nitrogen, total ammonia, nitrite + nitrate), dissolved oxygen, total hardness, total alkalinity, total phosphorus, pH, turbidity and water temperature were performed at all sampling sites. In addition, the density of the zooplankton groups Copepoda (adults and nauplii), Rotifera and Cladocera was determined. Results Regarding the changes between the quality variables of the affluent and effluent water of the pond, the outlet water showed a significant increase only in the variable total alkalinity. Rotifers were the most abundant organisms, and nauplii Copepoda showed a significant increase in the density of organisms in the middle of the pond compared to the inlet water. Both the redundancy analysis (RDA) and the Spearman correlation matrix revealed that zooplanktonic groups are associated with certain physicochemical variables of the water. According to the Analysis of Indicator Species (IndVal), the evaluated organisms are not related to bioindicator species in this environment. Conclusions Therefore, intensive production of O. niloticus caused changes only in the total alkalinity of the pond water. The zooplanktonic organisms correlated with the physicochemical variables of the water and between the groups, and did not show potential for bioindicators of water quality in the different locations of the pond.
EXPLORING INSIGHTS FROM ONLINE STUDENTS: ENHANCING THE DESIGN AND DEVELOPMENT OF INTELLIGENT TEXTBOOKS FOR THE FUTURE OF ONLINE EDUCATION
Authors: Lee Jeonghyun , Soylu Meryem Yilmaz , Ou Chaohua
Published: November 2023

The global pandemic accelerated the shift to remote teaching, leading to a rise in digital course materials such as textbooks. However, existing literature indicates that there is limited research on how online students utilize digital textbooks as well as on the features they find valuable for their online learning experiences and desire to aid their learning. Therefore, the purpose of this research was to explore the experiences and perceptions among diverse online students and then draw implications for the design of future intelligent textbooks. This study surveyed online degree-seeking students (n = 1236) from three different institutions in the United States in 2022. Based on the mixed-method research design, this exploratory study used qualitative data from open-ended questions and quantitative data from closed-ended questions to theme patterns of response. The results indicated that most participants have used at least one digital textbook, and in general they were familiar with such features as searching, visuals, and embedded assessments. These features, associated with self-directed and multimedia learning, received more positive ratings compared to adaptive or personalized learning features such as chatbots and recommended content. In the findings of the study, surveyed participants described future intelligent digital textbooks to be ideal for self-directed learning, since they can accommodate diverse learning needs and are flexible and affordable. Overall, this study provides insights into future intelligent textbooks and other digital materials as a comprehensive learning system and supports their use for empowering online learners to go beyond text-based learning and enhancing their digital learning experience.
ENVIRONMENTAL GOVERNANCE IN RUSSIA: DYNAMICS OF THE INTENSITY OF ENVIRONMENTAL REGULATION
Authors:   Perm State University, Turceva K. P.
Published: November 2023

Environmental governance is one of the practices of the regional authorities' activities to influence various categories of nature users in order to change their behavior. Various methods are used to quantify the process of environmental governance, among which is the assessment of the intensity of environmental regulation, focused on identifying the degree of activity and effectiveness of measures taken by the state to prevent damage to the environment. In this paper, we will attempt to adapt this indicator to the analysis of the environmental activities of the constituent entities of the Russian Federation. Furthermore, we will try to demonstrate that the change in its value is influenced by the degree of development of regional environmental legislation, the effectiveness of the implementation of regional state programs and environmental cooperation between neighboring regions. It is proposed to analyze the intensity of environmental regulation in the Russian context as an assessment of the effectiveness of direct measures of regional authorities to prevent and eliminate environmental pollution.
POLITICAL REALISM AS THE EMBODIMENT OF CHRISTIAN POLITICS: THE CONCEPT OF F.A. STEPUN
Authors:   National Research University “Higher School of Economics”, Girinsky A. A.
Published: November 2023

This article analyzes the political and philosophical views of the Russian philosopher and sociologist F.A. Stepun. The study briefly outlines his views on the nature of politics, as well as the basic principles of building it in the era of ideocracies and the triumph of ''secular utopias''. Stepun's article "Christianity and Politics'' (1933), where he proclaims the basic principles of his political doctrine, forms the basis for this study. Stepun argues that Western modernity, due to its abandonment of Christian cultural foundations, is at risk of "sacralization" of the political, turning politics into a tool for radical correction of human life on secular grounds. Stepun believes this view is dangerous, as it leads to an increase in violence and the emergence of radical utopian ideologies. Instead, Stepun proposes a return to the principles of "political realism". The study presents the point of view that Stepun's idea is an organic continuation and development of the main line of Russian political philosophy. Its main objective used to be the "conservative legitimization" of the Western project of modernity, designed to find the necessary philosophical tools for the rehabilitation of the Christian foundations of culture in the world of "modernity".
Population of the Bratsk-Ust-Ilimsk Complex: The Making and Current Demographic Situation
Authors: Tsykunov Grigory
Published: November 2023

The article deals with the historical and current problems of the population of the Bratsk-Ust-­Ilimsk territorial production complex, located in the Middle Angara region of the Irkutsk region. The main stages of the settlement of the territory associated with the economic development of the region are singled out. The author notes the special role of the state in attracting and resettling the population, providing financial, material and other assistance to migrants. The author focuses on the formation of the population of the Bratsk-Ust-­Ilim complex in the Soviet period, reveals the relationship between the processes of industrial development of the region and demographic processes. This is confirmed by the dynamics of the population, which is closely related to the main stages in the formation of the territorial production complex. The article examines the features of the natural and mechanical movement of the population, their share in the dynamics of the population, the impact of the industrial complex on the urban development of the region, which led to a sharp reduction in the rural population. The article analyzes the current demographic situation, characterized by a large migration outflow and natural population decline, which ultimately affected the progressive decline in the total population of the territorial production complex.
Achieving the Purpose of Criminal Proceedings in the Conditions of Digitalization: Analysis of Russian and Foreign Experience
Authors: Mironova Ekaterina
Published: November 2023

Digitization has certainly become a trend in the last decade, it has been consistently strengthening on a worldwide scale and its potential has been growing unstoppably. Digital technologies, which have become common in different spheres, are being gradually introduced in the work of law enforcement and judiciary bodies. In connection with these processes, there is a necessity to study the impact of digital technologies on the purpose, goals, and tasks of criminal proceedings. The need for such research is all the more evident in light of the problems of comparative law studies as different countries are currently at different stages of digitization, so the experience of more advanced countries is relevant for those with fewer achievements in digitization. In this article, the author analyzes the impact of digitization on the purpose, goals, and tasks of criminal proceedings in Russia, China, the UK and the USA. It was established that there have been no changes in the legislative regulation of their basic clauses. Currently, the legal regulation of the goal-setting of criminal proceedings remains stable in the face of recent digital trends. The main object of the research is to study how the purpose of criminal proceedings could be reached in view of the influence of digital transformations that the society is going through. It is concluded that such influence fluctuates from totally positive to extremely negative, associated with unstudied (insufficiently studied) risks and threats to the rights of a person in the criminal process and, consequently, to the purpose of criminal proceedings. The greatest threats are associated with the so-called end-to-end digital technologies, which include artificial intelligence, neural technologies, big data, blockchain, and others. The necessity of international and national ethical and legal regulation of the development and use of the abovementioned digital technologies is proven. The author analyzes the existing acts of regulating the ethical aspects of using digital technologies with cognitive functions. It is concluded that the documents that have already been adopted are mostly acts of soft law, and that it is necessary to adopt corresponding ethical and legal norms of a universally binding nature.
MAXILLOFACIAL RADIOLOGY Nevoid Basal Cell Carcinoma Syndrome
Authors: Merbold Lené , Yakoob Zarah
Published: November 2023

An 18-year-old male patient presented at our dental clinic in 2009 for a dental assessment. A panoramic radiograph was taken to evaluate dental crowning (Figure 1). An incidental finding was noted in the right maxilla, presenting as a well-demarcated, round, unilocular, radiolucent lesion with a corticated rim extending from the right maxillary tuberosity area to distal of the 16 causing. impaction of the 18. A biopsy was taken and diagnosed as an odontogenic keratocyst (OKC) that was subsequently enucleated. In 2021 the patient returned, and another panoramic radiograph (Figure 2) and a Waters view was taken where calcification of the falx cerebri was seen (Figure 3). On the panoramic radiograph an additional mandibular lesion was visible that presented as a well-demarcated, round, unilocular, radiolucent lesion with a corticated rim extending from distal of the 46 into the missing 47, 48 area. A CBCT was then. taken to further analyse the lesions (Figure 4). A biopsy was taken in the right posterior mandible and diagnosed as an OKC. In 2023 the patient returned and a CBCT was taken. The right maxilla showed increased bone density adjacent to the enucleated lesion (Figure 5).
Working with patient-derived intestinal/colonic fibroblasts v1
Authors: Karakasheva Tatiana
Published: November 2023

This is a protocol for working with patient-derived fibroblasts isolated from intestinal or colonic biopsies.
Immunohistochemistry on free-floating and paraffin-embedded tissue sections v1
Authors: Chou Ching-Chieh , Frydman Judith
Published: November 2023

This protocol is used for free-floating frozen (30-50 microns) and paraffin-embedded (10 microns) tissue sections.
Rapid Staining Technique for Visualizing Arbuscular Mycorrhizal Fungi (AMF) Colonization in Legume Roots v1
Authors: Arthikala Manoj-Kumar , Nanjareddy Kalpana
Published: November 2023

This protocol outlines a rapid staining technique for visualizing Arbuscular Mycorrhizal Fungi (AMF) colonization in legume roots. Careful sample selection is emphasized, avoiding stressed or diseased plants that may compromise mycorrhizal associations. Root sampling involves gentle extraction to prevent damage to mycorrhizal structures. The FAA fixative is recommended for preserving roots before staining. Following fixation, a meticulous staining process involves successive treatments with KOH, HCl, Trypan Blue stain, and an acetic acid:glycerol:distilled water solution. Stained roots, mounted on microscopic slides with 30% glycerol, are examined under a light microscope. The protocol provides detailed steps, from sample collection to microscopic observation, allowing researchers to efficiently visualize and document fungal structures, including extra-radicle hyphae, intra-radicle structures, vesicles, and arbuscules. This technique facilitates accurate assessment of mycorrhizal colonization in legume roots, contributing to a better understanding of plant-fungal symbiotic interactions.
Rye Broth Recipe v1
Authors: Lee Diana
Published: November 2023

This method describes the systematic preparation of a Rye-Based Broth for use in microbiological cultures. The broth consists of rye flour, sucrose, and, optionally, B-sitosterol dissolved in dichloromethane. The method involves the careful mixing of ingredients, filtration, and handling of dichloromethane (optional), followed by autoclaving to sterilize the broth.
A RESEARCH ON THE HAY YIELD AND QUALITY OF ALFALFA CULTIVARS WITH DIFFERENT FALL DORMANCY RATES UNDER MEDITERRANEAN CLIMATE CONDITIONS
Authors: DÖNMEZ Hasan Beytullah , HATİPOĞLU Rüştü
Published: November 2023

This research was carried out as two separate trials established in two different years to determine the effects

of different seed ratios and harvest stages of different annual companion crop species on the hay yield and

botanical composition of a pasture mixture under Mediterranean climate conditions. The field trials were

established in a randomized complete block with a split-plot arrangement in three replications. The research

results showed that barley, annual ryegrass, and berseem clover can be utilized as companion crops in

artificial pasture systems. The inclusion of these companion crop species in the pasture mixture resulted in an

increase in forage yield and a significant decrease in weed infestation. While delaying the harvest stage of the

companion crop does not have a notable effect on the proportion of legumes and weeds in the total biomass, it

significantly enhances the dry forage yield and the proportion of grasses in the overall biomass of the mixture.
Выделение микроорганизмов, способных продуцировать биосурфактанты, из органических отходов
Authors:   Казанский (Приволжский) федеральный университет, Бикташева Л.Р. , Кириченко А.А.
Published: November 2023

Биосурфактанты, они же биологические поверхностно-активные вещества, образуемые микроорганизмами, пользуются все возрастающим интересом благодаря широким возможностям их применения. Преимуществами этих веществ является высокая биоразлагаемость и безопасность для окружающей среды. В сельском хозяйстве существуют несколько областей их применения. Во-первых, биосурфактанты, обладая способностью к изменению поверхностного натяжения, возможно применять в качестве адъювантов. Во-вторых, биосурфактанты могут быть использованы в качестве фунгицидов, благодаря их способности подавлять рост фитопатогенных грибов. Массовое применение биосурфактантов, однако ограничено высокой стоимостью их производства. Одним из факторов высокой стоимости является цена субстратов для роста микроорганизмов. Решением этой проблемы может стать использование органических отходов в качестве субстратов. Применение отходов будет способствовать как снижению издержек при производстве биосурфактантов, так и повторному применению данных отходов. Среди отходов, исследуемых в качестве субстратов, можно выделить промышленные, сельскохозяйственные и пищевые отходы. В ходе нашей работы был проведен скрининг микроорганизмов из органических отходов, способных продуцировать биосурфактанты. Для исследования были выбраны и отобраны следующие виды отходов – сырая нефть, нефтезагрязненные почвы, жмых подсолнечника, масло после жарки и отработанное моторное масло. Микроорганизмы культивировали на минеральной среде, используя отход в качестве единственного источника углерода. Был выделен 21 изолят микроорганизмов, продуцирующих биосурфактанты, которые были охарактеризованы с точки зрения изменения поверхностного натяжения воды и эмульгирующих способностей. Установлено, что наиболее эффективными штаммами с точки зрения уменьшения поверхностного натяжения были – Amo (моторное масло), Csc и Esc (жмых подсолнечника), Ao и Bo (сырая нефть), показывая поверхностное натяжение в диапазоне 21,6-35,8 мН/м. Данные штаммы имеют значения поверхностного натяжения, сравнимые с показателями химических ПАВ, что указывает на их высокую эффективность. Отмечено, что наибольшей эмульгирующей активностью, по данным индекса эмульгирования равному 50%, обладают штаммы Bmo, Cmo (моторное масло), Csc (жмых подсолнечника), Bo (сырая нефть). Штамм Awfo показывают минимальную эмульгирующую активность равную 0%. В результате данной работы из маслосодержащих органических отходов были выделены микроорганизмы, обладающие способностью к синтезу биосурфактантов. Наибольшей эффективностью согласно высоким индексам эмульгирования и уровням снижения поверхностного натяжения, обладают биосурфактанты, произведенные штаммами Csc, Esc, Ao и Bo. Работа выполнена при финансовой поддержке Российского научного фонда, грант № 23-24-00611.
Graduate School Professor’s Perception Towards Teaching Public Ethics
Authors: Rome B. Moralista  , Roger B. Rueda
Published: November 2023

In the dynamic landscape of higher education, the teaching of public ethics in graduate programs has gained increasing significance. Graduate school professors play a pivotal role in shaping the ethical perspectives and practices of future professionals and leaders. This study delves into the attitudes, beliefs, practices, and challenges encountered by these professors in the domain of public ethics education. A mixed-method research approach was employed, encompassing surveys and in-depth interviews with a diverse group of graduate school professors. The study explored their attitudes towards public ethics education, the perceived relevance of ethics across academic disciplines, pedagogical approaches employed, and challenges faced in integrating ethics into their curriculum. The study employed thematic analysis to uncover nuanced insights from qualitative data and statistical analysis to derive quantitative trends. Quantitative analysis revealed a prevailing positive attitude among graduate school professors towards the importance of teaching public ethics. However, variations in perceived relevance across academic disciplines were observed. Professors reported diverse pedagogical approaches, ranging from case studies to ethical discussions, highlighting a rich educational landscape. Challenges included resource constraints and time limitations. The results underscore the commitment of graduate school professors to ethics education and the need for tailored approaches to address disciplinary variations. Diverse pedagogical approaches enrich the educational experience, while challenges present opportunities for institutional support and resource allocation. Interdisciplinary collaboration is recommended to bridge the gap between ethics education and various academic disciplines. This study illuminates the crucial role of graduate school professors in shaping ethical competencies among graduate students. Their positive attitudes, diverse teaching practices, and commitment to ethics education form a solid foundation for the continued integration of public ethics into graduate programs. Addressing challenges and promoting interdisciplinary collaboration will be instrumental in advancing ethics education and fostering ethically responsible professionals and leaders.
Jurassic heritance of the geomorphology in Mid Norway
Authors: Olesen Odleiv , Rueslåtten Håkon G. , Schönenberger Jasmin , Smelror Morten , van der Lelij Roelant , Larsen Bjørn Eskil , Olsen Lars , Baranwal Vikas , Bjørlykke Arne , Brönner Marco , Gellein Jomar , Rønning Jan Steinar
Published: November 2023

The age and formation of the Scandinavian mountains and the Norwegian strandflat have long been the subject of dispute. Some researchers argue that the present-day mountains are remains of the Caledonian orogen while others claim that the Caledonian nappes after erosion were buried by Mesozoic sediments and subsequently exhumed. In order to clarify these issues, we have studied remains of chemically weathered rocks (saprolites) from the coast to the interior of central Norway. The multidisciplinary study includes digital topography, electrical resistivity tomography (ERT), XRD, XRF, palynological analyses and K–Ar dating of samples from outcrops, trenches and core drilling. The coastal areas are dominated by an outer strandflat and an inner joint-valley landscape, while the interior is characterised by smoother landscapes referred to as palaeo-surfaces. Remnants of pre–Tertiary weathering occur in the joint valley landscape as well as on the palaeo-surfaces. The saprolites are found within fault- and fracture-zones and at depths exceeding 50 m in drillholes. It is suggested that the old saprolites were strongly eroded along the coast and in the fjords and valleys such as in Orkdalen and Sunndalen. K–Ar dating of mainland clay alteration most frequently yielded Jurassic ages along a profile extending from the coast to the Dovrefjell mountains (c. 1400 m a.s.l.). The formation age of the smectite- and kaolinite-containing saprolites seems to be almost contemporaneous along this profile implying that the entire area was subject to weathering in a warm and humid climate, such as prevailed during the Late Triassic and Jurassic. Palynological residues containing thermally altered Triassic and Jurassic pollen and spores in the clay-infected bedrock lend support to the saprolite interpretation. The Mesozoic landscape in central Norway was consequently shaped by uplift and deep weathering in the Jurassic. The entire Trøndelag county was most likely covered by Mesozoic sedimentary rocks until Cenozoic exhumation. The landscape was modified by Cenozoic tectonic uplift and erosion, and finally reworked by Pleistocene glacial erosion. We therefore conclude that both the observed saprolites and the shape of the present-day landscape in central Norway give a strong impression of the original Jurassic weathering surface.
Control and management of water quality for Nile tilapia fish in net tanks based on fuzzy modeling
Authors: Mastelini Vinícius , Ramos Queiroz Timóteo , Almeida Gabriel Filho Luís Roberto , Mollo Neto Mario
Published: November 2023

Being classified as one of the most important species for fish farming, the Nile tilapia has seen a huge increase in breeding worldwide. As in any cultural medium, dealing with the quality of the medium in which it is grown guarantees a large part of the success of the process, being of equal importance, in this case, the quality of the water. Taking advantage of existing mathematical models, humans were able to measure and design best practices in virtually all areas, pointing to its great functionality, this article used the Fuzzy logic mathematical model together with Mamdani inference to analyze water quality scenarios and their consequences, various environments, variables, capable of directly affecting fish farming. The purpose was to use the MatLab scientific software to cross these variables with the possible output scenarios, facilitating the producer's decision-making. As a result of the research, it was possible to develop an algorithm to be embedded in a mobile application in the future with fuzzy mathematical modeling, with a Mamdani inference system for management and control of water quality in Nile Tilapia fish farming. The same will be made available to these breeders, since it has a structure of rules, aiming at the delivery of scientific information that collaborates with the best cultivation practices, improving production and profitability, through decision support to fish farmers.