bluuebunny/crossref_metadata_2025 huggingface dataset:
Philippine Retirement Authority Policy Development with Impact Assessment
Authors: Patalinghug Epictetus , Tabuga Aubrey , Baiño Madeleine Louise , Ruiz Mark Gerard , Ortiz Ma. Kristina , Astilla-Magoncia Danika ,   Philippine Institute for Development Studies,   Philippine Retirement Authority
Published: October 2024

This study's third phase evaluates the regulatory impact analysis (RIA) of policy recommendations aimed at enhancing the Philippine Retirement Authority's (PRA) retirement program, focusing on competitiveness and sustainability. Utilizing methodologies such as benefit-cost analysis, breakeven analysis, cost-effectiveness analysis, and regression analysis, the study compares targeting foreign retirees aged 40 and above with those aged 50 and above, assesses the cost-effectiveness of current PRA policies, and determines breakeven volumes. Findings reveal that lowering the minimum retirement age to 35 (as a proxy for 40) improved the benefit-cost ratio compared to when the age requirement was 50. However, since 2017, the benefit-cost ratio for the 35+ program has declined due to rising costs outpacing benefits. Cost-effectiveness analysis shows a significant increase in cost-to-retiree ratios post-2017. Breakeven analysis indicates that the number of retirees required ranges from 652 to 759, with breakeven sales volumes between PHP 35 million and PHP 39 million, though these figures have escalated post-2017. Regression analysis identifies that consumer sentiment, exchange rates, and real estate expenditures positively impact foreign retiree volumes, with forecasts showing an upward trend, though lower than pre-pandemic levels. The study concludes that the Philippine retirement industry remains economically viable and attractive. It suggests that PRA's competitiveness does not hinge on being a low-cost provider but rather on a targeted market strategy that builds customer loyalty. Embracing a younger retiree age requirement should be balanced with managing public perceptions and legislative concerns regarding program viability and social impacts.
Teachers’ Practice of Teaching Advanced Speech: The Case of Debre Markos University, Ethiopia
Authors:   Addis Ababa University, Addis Ababa, Ethiopia;, Tessera Endalew Molla , Anteneh Kassa Animaw ,   Addis Ababa University, Addis Ababa, Ethiopia;
Published: October 2024

Different studies have disclosed that most university students in Ethiopia lack communicative competence, and hence they cannot communicate effectively in English. This is caused by a number of factors, the major ones having to do with the curriculum, the process of teaching and learning, or the methods used in the assessment. This inquiry was made to look into the practice of teaching the Advanced Speech course. Forty-three students and six teachers were included in the study. Data were collected through in-depth interviews and classroom observation. The data revealed that most of the teachers were assigned to teach the Advanced Speech course against their will. Moreover, the student class size and seating arrangement were not appropriate for spoken courses. Teachers were not creating a conducive environment for the students to use the target language in real-life communication. The teachers’ main role was giving lectures; they were not supervising and guiding the students. Activities used to teach advanced speech were dull and pitched at the wrong level. This implies that teachers’ teaching practices were not effective to improve the students’ skill.
Campaña XXXII-2022 de excavaciones arqueológicas en Pintia (Padilla de Duero/Peñafiel. Valladolid)
Authors: Sanz Mínguez Carlos , Rodríguez Gutiérrez Elvira , Coria Noguera José Carlos
Published: October 2024

El trabajo ofrece los resultados de las excavaciones desarrolladas en diversos puntos de la Zona Arqueológica Pintia durante el año 2022. En primer lugar, se retomaron los trabajos en el área urbana de Las Quintanas, dentro de un proyecto de recuperación y puesta en valor que busca mostrar las sucesivas fases de ocupación del oppidum a través de la ventana estratigráfica que supuso la apertura de un pozo artesiano fallido en época romana. Paralelamente a este proyecto museístico, otro de los objetivos en esta zona es el acceso a estructuras termoalteradas para poder datar cada uno de los niveles mediante paleomagnetismo. Por todo ello, en esta campaña se abrió una cata en el poblado para documentar el nivel indígena ubicado por debajo del último vacceo excavado en extensión en 2006. En segundo lugar, se llevaron a cabo sondeos arqueológicos en distintas áreas periurbanas de la ciudad con el objeto de documentar y evaluar los daños efectuados por acciones furtivas con detector de metales en septiembre de 2021. Los resultados de estas catas han permitido certificar el uso como vertederos, áreas de trabajo y/o frecuentación de estas zonas periféricas de la ciudad vacceo-romana de Pintia.
Assessing stochastic dominance of downside and upside financial risk profiles using the block maxima method in extreme value theory
Authors: Li Simon
Published: October 2024

This paper aims to assess the stochastic dominance of the extreme downside (negative return) and upside (positive return) risk profiles of three US stock market indices, namely NASDAQ Composite, S&P 500 and Dow Jones Industrial Average (DJIA) based on the block maxima method in extreme value theory. The extreme downside and upside risk profiles were developed using two datasets of 360 monthly minimum and maximum daily log returns respectively (from January 1992 to December 2021). Extreme losses beyond the 80th percentile (corresponding to a tail probability of less than 0.2) of the theoretical extreme risk profiles were adopted to investigate stochastic dominance. Pairwise comparisons show that the DJIA stochastically dominates the other two indices in both extreme negative and positive returns. Moreover, the extreme upside risk profile of the DJIA stochastically dominates its extreme downside risk profile. The paper finds that investment in short positions (encountering upside risk) provides the least extreme risk compared with long positions (encountering downside risk) for the DJIA, as well as both short and long positions for the S&P 500 and NASDAQ Composite.
Silicon Valley Bank: What can be learned from its collapse
Authors: Lindo Steve
Published: October 2024

The collapse of Silicon Valley Bank (SVB) in March 2023 and its resulting impact on global banking markets have already been exhaustively reported and analysed. This paper examines these events through two different but complementary lenses, root cause analysis and key assumptions check. Together, these methods provide a detailed picture of the causes and derive fact-based conclusions intended to prevent repetition of the mistakes made by SVB's executives and the US banking authorities.
Clinical Psychology Interns' Lived Experiences With Suicidal Clients
Authors: Elayda Elaine , Distor John Mark
Published: October 2024

This paper explores the lived experiences of clinical psychology interns who have encountered suicidal clients during their internship. Employing qualitative phenomenological investigation, semistructured interviews were conducted and analyzed using interpretative phenomenological analysis (IPA). The study employed purposive sampling and gathered valuable data from 8 clinical psychology interns who were all taking a master's degree in Clinical Psychology. The results highlighted that those encounters with suicidal clients triggered various reactions among interns, leading to self-doubt and a sense of unpreparedness in handling such cases. Many interns struggled with managing their emotions, especially when clients' traumas mirrored their experiences. The study emphasized the importance of a robust support system in helping interns cope with the challenges of their work. The results included a heightened need for supervision among interns, as they faced intense emotional challenges when working with suicidal clients. Supervision emerged as a critical component in helping them process these experiences. Regular check-ins with supervisors not only provided emotional support but also offered practical strategies for managing client interactions. This guidance helped interns develop coping mechanisms and build resilience, fostering their professional growth and confidence in handling difficult cases. Despite the challenges, the interns found purpose in witnessing significant client progress and emphasized the importance of self-care and ongoing training to prepare future clinicians for similar experiences.
Macrocriminalidad y desastres
Authors: García Álvarez Pastora
Published: October 2024

La presente obra colectiva abre una línea de investigación interdisciplinaria sobre la macrocriminalidad en sentido amplio, a la que han contribuido estudiosos de España e Italia, y que se concreta en este caso en el estudio de los desastres naturales desde las perspectivas jurídica y criminológica. Los distintos capítulos analizan temas concretos que se sitúan en la intersección entre «macrocriminalidad» y «desastres», tales como el modelo de tipificación de los delitos medioambientales en España; la Directiva europea para la protección del medio ambiente a través del Derecho penal desde una perspectiva Victimológica; el nexo de riesgo y el ámbito de tutela en la imputación del resultado de desastre en el Derecho penal italiano; la multidireccionalidad del riesgo en los delitos de desastre medioambiental en el Derecho penal italiano; la victimización medioambiental estudiada a través de la metodología de los «soliloquios itinerantes»; y la gestión de los riesgos naturales como una cuestión de derechos humanos.
Macrocriminalidad y desastres
Authors: Natali Lorenzo
Published: October 2024

La presente obra colectiva abre una línea de investigación interdisciplinaria sobre la macrocriminalidad en sentido amplio, a la que han contribuido estudiosos de España e Italia, y que se concreta en este caso en el estudio de los desastres naturales desde las perspectivas jurídica y criminológica. Los distintos capítulos analizan temas concretos que se sitúan en la intersección entre «macrocriminalidad» y «desastres», tales como el modelo de tipificación de los delitos medioambientales en España; la Directiva europea para la protección del medio ambiente a través del Derecho penal desde una perspectiva Victimológica; el nexo de riesgo y el ámbito de tutela en la imputación del resultado de desastre en el Derecho penal italiano; la multidireccionalidad del riesgo en los delitos de desastre medioambiental en el Derecho penal italiano; la victimización medioambiental estudiada a través de la metodología de los «soliloquios itinerantes»; y la gestión de los riesgos naturales como una cuestión de derechos humanos.
Macrocriminalidad y desastres
Authors: Zango-Pascual Marga
Published: October 2024

La presente obra colectiva abre una línea de investigación interdisciplinaria sobre la macrocriminalidad en sentido amplio, a la que han contribuido estudiosos de España e Italia, y que se concreta en este caso en el estudio de los desastres naturales desde las perspectivas jurídica y criminológica. Los distintos capítulos analizan temas concretos que se sitúan en la intersección entre «macrocriminalidad» y «desastres», tales como el modelo de tipificación de los delitos medioambientales en España; la Directiva europea para la protección del medio ambiente a través del Derecho penal desde una perspectiva Victimológica; el nexo de riesgo y el ámbito de tutela en la imputación del resultado de desastre en el Derecho penal italiano; la multidireccionalidad del riesgo en los delitos de desastre medioambiental en el Derecho penal italiano; la victimización medioambiental estudiada a través de la metodología de los «soliloquios itinerantes»; y la gestión de los riesgos naturales como una cuestión de derechos humanos.
ЎЗБЕКИСТОНДА СОВЕТ ДАВРИ МЕЪМОРЧИЛИГИ ВА ҚУРИЛИШ МАДАНИЯТИНИНГ ЎЗИГА ХОС ХУСУСИЯТЛАРИ
Authors: Haydarov Zuhriddin
Published: October 2024

This article reveals the main features of construction work carried out in Uzbekistan under Soviet rule, the subordination of this construction culture to ideology, the consolidation of national construction culture and traditions.
ASSISTÊNCIA DE ENFERMAGEM NA SAÚDE MENTAL DOS PORTADORES DE LINFANGIOLEIOMIOMATOSE
Authors:   Jose Willian de Aguiar, Santos Vitória Godoi dos , Mota Mariana Macedo
Published: October 2024

The importance of providing quality and knowledgeable care, and recognizing the impact generated on the mental health of patients with a rare disease, such as Lymphangioleiomyomatosis or LAM, advocating nursing care as essential. Objective: to highlight and inform the need for nursing care in the mental health of patients with LAM. Method: this is a bibliographic review, based on articles selected from the databases: Scientific Electronic Library (SciELO), Brazilian Society of Pulmonology and Tisiology, Google Scholar and the Ministry of Health. The inclusion criteria were articles that were published in the year 2020 to 2024, except for some cases where it was necessary to search for slightly older articles for a more complete research. Results: the nursing team, because it is on the front line of care and has a greater bond with patients, becomes responsible for providing proper care to people who have a rare disease, such as LAM, as this generates psychological illness. Knowing the subject, studying it and providing adequate assistance, thus reducing the impacts generated by this disease. Thus, providing guidance regarding the concept of LAM, the symptoms that may arise, how to reduce them, respecting the entire process and providing the emotional support they need. Conclusion: the presence of a nurse is necessary to provide the appropriate assistance to these patients. It is extremely important to have knowledge of LAM and its harms to the mental health of patients, enabling this professional to be able to provide the best possible care to a patient with a rare disease.
CINEMA, ARTE E VIRADAS ONTOLÓGICAS CINEMA, ART AND ONTOLOGICAL TURNINGS
Authors: Pontes Glycia Ruthênia Tomaz , Rocha Julianne do Nascimento , Chellappa Thiago
Published: October 2024

In this essay, we will explore the interrelationship between cinema, art and ontological turns, going through the concept of ontology, ontological turns, the importance of cinema and art as language builders and influence in relation to the fundamental understanding of existence, as we also seek illustrate the complexity and interdependence of these elements in the human experience. The methodology used is based on bibliographical research, bringing together information gathering through books and articles. In view of this, putting on the agenda the importance of the relationship between cinema, art and the ontological turn as a reflection on the nature of being and reality.
TRATAMENTO MULTIMODAL DE MASTOCITOMA CUTÂNEO CANINO: CIRURGIA RECONSTRUTIVA E QUIMIOTERAPIA ADJUVANTE – RELATO DE CASO
Authors: Christ Quezia Silva , Rosestolato Lucas
Published: October 2024

A oncologia é considerada de grande importância na medicina veterinária, onde as neoplasias estão relacionadas como a primeira causa de morte de animais de companhia. O mastocitoma canino é um dos tumores de pele mais comum em cães e gatos, sendo considerada a segunda neoplasia maligna mais frequente em cães. Os sinais clínicos são variados e vão depender da localização e do avanço da doença. O diagnóstico é baseado na anamnese, histórico e evolução da lesão, realização de exames complementares como análises citopatológica e histopatológica. O principal método de tratamento em casos de mastocitoma canino é a excisão cirúrgica, outras abordagens terapêuticas estão relacionadas com controle local como eletroquimioterapia ou sistêmicos, como a quimioterapia. Sendo assim o objetivo deste trabalho foi relatar o tratamento cirúrgico para excisão de mastocitoma cutâneo grau II alto grau, associado a técnica reconstrutiva, seguido de quimioterapia para controle sistêmico. O tratamento multimodal se mostrou eficiente, onde a paciente teve uma recuperação satisfatória não demonstrando sinais de metástase até o final do tratamento.
A SEGURANÇA DO PACIENTE
Authors: Pantoja Mateus Farias , Pinheiro Keniellry Daris
Published: October 2024

Objective: Promote training for nursing team professionals to reduce the risks of infections caused by invasive procedures. Methods: This study was based on a quantitative research, of an exploratory nature, conducted through field research. Results: The aim was to decrease hospital-acquired infections by raising awareness among the nursing team about the importance of following safety protocols. This included reducing the percentage of devices that could potentially aggravate risks for clients/patients. Final Considerations: The study highlighted the need for targeted training using the presented approach. It emphasized the importance of the entire team remaining vigilant in hygiene practices, handwashing, equipment cleaning, and proper execution of invasive procedures to minimize the risks of infection transmission and spread.
THOMAS HOBBES CONTRATO SOCIAL
Authors: Lima Leonardo Noro De
Published: October 2024

Este artigo fala sobre um dos principais filósofos políticos modernos: Thomas Hobbes e sua teoria do Contrato Social. Hobbes, em Leviatã, define o estado de natureza como um estágio pré-político onde a falta de poder centralizado resulta em uma guerra de todos contra todos. Nessa visão, para evitar enfrentar uma realidade tão caótica quanto a descrita acima, os indivíduos são forçados pelo medo e pela necessidade de autopreservação a entrar em um pacto social por meio do qual transferem seus direitos a um soberano absoluto cuja autoridade assegura a paz e a ordem. O estudo vai expor as principais ideias dessa teoria: o estado de natureza, o pacto social e o papel do soberano; além de sua aplicabilidade em contextos da política contemporânea. A pesquisa foi feita por meio de bibliografia e revisões das obras de ambos os críticos originais.
CONSIDERAÇÕES SOBRE O CONSERVADORISMO DE BURKE À LUZ DA SUA OBRA REFLECTIONS ON THE REVOLUTION IN FRANCE
Authors: Lima Leonardo Noro De
Published: October 2024

The paper  investigates the thought of Edmund Burke, trying to understand and giving special attention to the conservative philosophy by which the author underlies within his political philosophy. The research here described focuses especially on the analysis and approach present in the author's edifying work, Reflections on the Revolution in France, and how these approaches have contributed to spread and generate modern conservatism, relying on its approaches as values, such as tradition, defense of order, hierarchy, communitarianism and opposition to rationalism, for the idea of the people assuming power as a fundamental part of a conservative policy, thus against monarchical absolutism, which went against Burke's thought in the sense that power should be dissolved among all, and decision-making exercised taking into account multi-generational events, thus valuing traditions, so that these important ingredients construct Burke's arguments, which remains present in modern conservative thinking.
DIAGNÓSTICO CLÍNICO MOLECULAR DAS SÍNDROMES FEBRIS NA AMAZÔNIA OCIDENTAL: REVISÃO SISTEMÁTICA
Authors: Melo Jose Johnata Paiva de , Soares Carolina Pontes , Lobato Cirley Maria Oliveira
Published: October 2024

Introdução:As síndromes febris dengue, chikungunya e zika são consideradas arboviroses que podem ser transmitidas pelo mesmo vetor em regiões tropicais e subtropicais do mundo. Objetivo: Este trabalho de pesquisa tem como objetivo pesquisar e descrever sobre as arboviroses, incluindo as classificações e características que implicarão nas sintomatologia desta patologia que possui uma alta incidência no Brasil. Resultados: O Dengue vírus (DENV) e Zika vírus (ZIKV) pertencem ao mesmo gênero Flavivirus, possuem em sua estrutura genômica um RNA envelopado, em sentido positivo e de fita simples. Adicionalmente, o Chikungunya vírus (CHIKV) é um RNA vírus envelopado, em senso positivo e de cadeia simples, pertencente ao gênero Alphavirus. No Brasil o DENV circula desde a década de 80, com surtos anuais facilitado pela circulação de quatro sorotipos (DENV1- 4) com infecções, geralmente, sintomáticas podendo evoluir para manifestações hemorrágicas ou neurológicas fatais. O CHIKV foi inserido em 2014 causando epidemias e surtos, de uma doença debilitante podendo cursar em intensa artralgia, enquanto que o ZIKV ficou bastante conhecido depois do surto brasileiro em 2015, estando associado às consequências mais graves da infecção pelo vírus, com a Síndrome de Guillain-Barré e vários casos registrados de microcefalia em neonatos no surto. No estado do Acre há circulação simultânea dos três vírus, com predominância dos sorotipos DENV1-2, e foram registrados alguns casos de coinfecção. Conclusão: As arboviroses constituem um grave problema de saúde pública nas regiões subtropicais e tropicais por oferecem condições ecológicas favoráveis e apresentarem expressividade em morbidade e/ou mortalidade, sendo  necessário estudos que fortaleçam e contribuam para melhoria da qualidade das informações e conscientização da população sobre as arboviroses e suas sintomatologias.
A IMPORTÂNCIA DOS PROJETOS DE EXTENSÃO UNIVERSITÁRIA NO ENSINO TEÓRICO E PRÁTICO NOS CURSOS DA MEDICINA: USO DA FERRAMENTA CONSCIENTIZAÇÃO DA PRÁTICA DE UMA ROTINA SAUDÁVEL PARA PREVENÇÃO DE DOENÇAS.
Authors: Lopes Romário Mascena Amorim , Silva Filho Markinokoff Lima e , Alves Débora Larissa Rufino , Vasconcelos Kleber Vinicius Rodrigues de , Melo Klary Gheorgia Silveira Medeiros , Absalão André Cordeiro de Sousa , Lima Márcio José de Carvalho , Carvalho Louise Santana de , Teixeira Neto João Bosco Antunes , Nascimento Loreanne Gomes , Pereira Suzy Mary Ferreira
Published: October 2024

RESUMO: A educação nos cursos da área da saúde pode ser compreendida como um conjunto de saberes teóricos passados em sala de aula e práticas em laboratório, sendo ainda possível acumular experiências ainda como acadêmico, para além das horas de estágio regular, por meio de projetos voltados para atender a comunidade,  prevenção de doenças e promoção da saúde. (SILVA, et al. 2007; BRITO, 2021). Essas práticas educativas nesta área devem ser direcionadas para o desenvolvimento de capacidades individuais e coletivas visando do acadêmico, bem como para população à melhoria da qualidade de vida e saúde e melhora no autogerenciamento, principalmente quando relacionamos as doenças crônico-degenerativas. (BARROS, CARNEIRO, 2011).OBJETIVOS: Descrever o que é projeto de extensão universitária e os benefícios para o ensino superior, acadêmico e comunidade.  METODOLOGIA: Trata-se de uma revisão de literatura em bases indexadas scielo, pubmed, lilacs, utilizando os descritores Formação em saúde; Ensino, Pesquisa e Extensão; Interdisciplinaridade; Humanização do cuidado, Medicina, no período de 2004 a 2024.  RESULTADOS E DISCUSSÃO: Os artigos selecionados corroboram com a cerne dessa revisão que a trabalhos em grupos para realizar educação em saúde e favorecer a inter-relação profissional-usuário-família, e resultados positivos em auxiliar os mesmos a enfrentar de forma mais adequada às doenças crônicas e possibilitando o empoderamento de seu autocuidado. (SANTOS. 2011; NOVAES, 2021). CONCLUSÃO:É inquestionável que a Extensão Universitária  dispõe  de  um  potencial transformador das estruturas acadêmicas e sociais, uma vez que, as instituições garantem que os discentes obtenham uma formação mais integral, com o devido alinhamento do tripé: Ensino, Pesquisa e Extensão.
CRIAÇÃO DE UM PROTÓTIPO DE REVEZAMENTO DE BOMBAS COM RELÉ DO TIPO RVB
Authors: Gomes Rodrigo Santos , Pacheco Maria dos Anjos Fernandes
Published: October 2024

Um dos problemas mais críticos do século XXI diz respeito a uma possível escassez dos recursos naturais para as gerações futuras. Um destes recursos é a água, a qual vem apresentando redução quanto a sua disponibilidade em condições de potabilidade. O estudo apresenta como objetivo geral criar um sistema de comando de revezamento de bombas de água com o relé RVB. Em termos metodológicos, é um estudo bibliográfico, explicativo, qualitativo, sendo apoiado por um processo de prototipagem. Os protótipos são artefatos ainda não finalizados, mas cujo estado é o mais próximo possível de um produto. Neste estudo, é descrita a finalidade, os materiais e apresentado o painel elétrico, onde para duas bombas, o relé aciona a bomba 1, com a bomba 2 ficando inoperante e assim sucessivamente. Este protótipo é aplicável para sistemas de abastecimento de água residenciais, sendo que seu uso reduz o desperdício de água, colaborando assim para um futuro mais sustentável do planeta.
Clinical and epidemiological profiles of newborns from twin pregnancies in Hassan II University Hospital of Fez, Morocco
Authors: Rahmouni Safae , Skalli Houssaini Khadija , Ouanouche El Hassan , Stati Soukaina , Oukachou Driss , Hmami Fouzia
Published: October 2024

Twin pregnancies are high-risk pregnancies, and delivery of twins poses variable difficulties due to the complexity of obstetrical mechanics and the frequency of dystocic presentations. Twin births represent a real public health issue and are responsible for a high rate of perinatal mortality. This study aims to report on newborns' epidemiological, clinical, therapeutic, and evolutionary aspects from twin pregnancies hospitalized in the Neonatal Intensive Care and Neonatology Department of the Hassan II University Hospital, Fez. A cross-sectional, retrospective, and descriptive study was conducted on newborns from twin pregnancies hospitalized in the neonatal and neonatal intensive care unit over two and a half years. Statistical analyses were performed using the JAMOVI software. Qualitative variables were expressed as frequencies and percentages, while quantitative variables were presented as means with standard deviations (SD) or medians with interquartile ranges (IQR). A total of 96 newborns from twin pregnancies were collected. The average maternal age was 29.7 years. Maternal complications during pregnancy were dominated by the threat of premature delivery (38.77%), premature rupture of membranes 5.49%), and urinary and cervicovaginal infectious complications (12.24%).89.8% of deliveries were medicalized, with vaginal delivery being the most common (69.39%).91.67% of newborns were premature, thus dominating neonatal morbidity. The average weight was 1585g +/- 425g.76.04% of newborns presented with neonatal respiratory distress, the most frequent etiology of which was hyaline membrane disease. These neonates presented other complications: neonatal jaundice (62.5%), perinatal anoxo-ischemia (6.25%), and transfusion-transfusion syndrome (6.25%). The neonatal mortality rate was 31.25%, with the leading cause being severe neonatal infection (56.67%). The prevalence of twin pregnancies is on the rise, with a high prevalence of prematurity among newborns, requiring special attention to limit complications.
Optimization and Validation of Extrusion Process Parameters for the Sensory Characteristics of Extruded Aerial Yam and Soybean Flour Blends
Authors: Umoh Enobong Okon , Iwe Madu Ofo , Ojimelukwe Philippa C.
Published: October 2024

The aim of this study was to optimize and validate the extrusion process parameters (barrel temperature, screw speed, and feed moisture) for the sensory properties (texture, taste, appearance, and aroma) of extrudates made from blends of soybean and aerial yam flours. Five levels of barrel temperature (95, 100, 105, 110, and 115 °C), screw speed (85, 100, 115, 130, and 145 rpm), and feed moisture (31, 33, 35, 37, and 39%) were employed in 20 runs of the response surface methodology (RSM), which was based on the Box-Behnken design with three variables. A single-screw extruder at the laboratory scale was used to carry out the extrusion procedure. A high regression coefficient (R2 ≥ 0.9) indicates that the models are useful for navigating the design space. Numerical optimization results indicated that the optimal extrusion process parameters - barrel temperature of 114.12 °C, screw speed of 100.56 rpm, and feed moisture of 38.02% - produced extrudates with optimal sensory property scores of 5.34 for texture, 4.91 for taste, 6.97 for appearance, and 5.80 for aroma, with a desirability of 0.943. The correlation between the predicted and experimental values yielded a high coefficient of determination, indicating a good correlation. The “Fit and Diagnostic Case” statistics showed a low range of deviations between the predicted and observed values for the sensory characteristics. Therefore, the generated quadratic model accurately predicts the sensory characteristics of aerial yam-soybean flour blends and is thus validated.
Kebijakan Zonasi Sekolah di Indonesia: Kajian Literatur Mengenai Penyimpangan dan Implikasinya
Authors:   Universitas Muria Kudus, Sutanto Sutanto
Published: October 2024

Kebijakan zonasi sekolah di Indonesia diimplementasikan untuk meningkatkan pemerataan akses pendidikan dan mengurangi kesenjangan antar sekolah. Namun, implementasi kebijakan ini sering kali mengalami penyimpangan yang menghambat pencapaian tujuan utamanya. Penelitian ini bertujuan untuk mengkaji literatur yang ada mengenai penyimpangan dalam implementasi kebijakan zonasi sekolah di Indonesia. Metode penelitian yang digunakan adalah kajian literatur dengan mengumpulkan dan menganalisis berbagai sumber yang relevan. Hasil penelitian menunjukkan bahwa penyimpangan seperti pemalsuan alamat domisili, manipulasi dokumen administrasi, kurangnya sosialisasi, infrastruktur teknis yang tidak memadai, serta pengawasan yang lemah merupakan beberapa tantangan utama. Penyimpangan ini memiliki implikasi serius terhadap pemerataan akses dan kualitas pendidikan. Rekomendasi kebijakan yang diusulkan meliputi peningkatan sosialisasi, penguatan pengawasan, peningkatan infrastruktur teknologi, pemerataan kualitas sekolah, partisipasi masyarakat, fleksibilitas dalam kebijakan zonasi, evaluasi berkala, dan kolaborasi antar lembaga. Penelitian ini juga memiliki beberapa keterbatasan, termasuk ketergantungan pada sumber sekunder dan kurangnya analisis statistik mendalam. Oleh karena itu, diperlukan penelitian lebih lanjut untuk memahami lebih dalam mengenai implementasi kebijakan zonasi sekolah di Indonesia.
Efektivitas Penerapan Metode Teaching at the Right Level dalam Meningkatkan Kemampuan Literasi Siswa di Kelas 2 SD Negeri 2 Plosorejo: Studi Kasus
Authors:   Dinas Pendidikan Kabupaten Grobogan, Susanti Susanti
Published: October 2024

Penelitian ini bertujuan untuk mengevaluasi efektivitas penerapan metode Teaching at the Right Level (TaRL) di kelas 2 SD Negeri 2 Plosorejo, Kecamatan Tawangharjo. Pendekatan yang digunakan adalah studi kasus dengan metode kualitatif, di mana data dikumpulkan melalui observasi, wawancara mendalam, dan analisis dokumen. Hasil penelitian menunjukkan bahwa penerapan metode TaRL meningkatkan kemampuan literasi siswa dan motivasi belajar. Siswa yang dikelompokkan berdasarkan tingkat kemampuan mereka menunjukkan peningkatan signifikan dalam kemampuan membaca dan pemahaman teks. Meskipun terdapat tantangan dalam implementasi, seperti kebutuhan pelatihan guru dan keterbatasan sumber daya, manfaat yang diperoleh lebih besar. Penelitian ini memberikan bukti empiris yang mendukung penggunaan metode TaRL dalam meningkatkan kualitas pendidikan dasar di Indonesia.
Po-éticas pretas de [re] existência
Authors: Caetano Nina , Sousa Marcia
Published: October 2024

Brasil. Dezembro de 2020. Aqui, como em outras partes do mundo, explodem manifestações e protestos bradando: Vidas Negras Importam! Intelectuais negras e negros, aqui, como em outras partes do mundo, ocupam as redes sociais, abrindo espaços de fala para a denúncia do racismo estrutural. Artistas negras e negros ocupam a cena, numa efervescência política e estética inegável. Aqui, como em outras partes do mundo, é perceptível a urgência da produção de novos futuros e de possibilidades de existência para vidas negras. E é deste desejo, do desejo de cimentar ficções capazes de nos fazer projetar sonhos coletivos (Mombaça, 2016), que nasce o dossiê Po-éticas Pretas de [Re]Existência.
Especificamente, optamos por publicar aqui materiais que estão para além dos formatos usuais encontrados em pesquisas acadêmicas na área das artes, como artigos e resenhas, e trouxemos também relatos de experiência, narrativas autobiográficas, poemas-canções e fotomontagens de artistas e escritoras negras e negros que abordam o tema da (re)existência preto-po-ética.
Coletânea de Poemas e narrativas autobiográficas
Authors: Sousa Marcia , Caetano Nina , Da Iola Luiza , Sabino Nívea , Gravano Joyce , Mariano Bárbara , Shinzato Batia Jello
Published: October 2024

Coletânea de Poemas e narrativas autobiográficas.   Org: Nina Caetano e Márcia Sousa Autoras convidadas: Luiza da Iola, Nívea Sabino, Joyce Gravano, Bárbara Mariano e  Batia Jello (Iyalorixa Sandide). Diagramação: Deyla Dayanne Rabelo Silva.
Das Imagens da Sociedade do Espetáculo às Imagens Vaga-lumes
Authors: Bortolini Neide
Published: October 2024

Este texto trata das contingências atuais da sociedade brasileira, em face da pandemia mundial causada pela COVID19, à luz de elementos como negacionismo, neofascismo e o caos político presente em uma sociedade espetacularizada. Tais situações são analisadas pela perspectiva da imagem, à luz de pensamentos que fizeram a resistência ao fascismo, na Europa no século passado. Esta fala retrata uma participação em uma das mesas promovida pelo VII Seminário de Pesquisa do Programa de Pós-Graduação em Artes Cênicas da Universidade Federal de Ouro Preto, em 2020.
Yahudilikte Şiddetin Meşrulaştırıcı Unsuru Tanah
Authors: Sayar Serkan
Published: October 2024

Bu çalışmada, Yahudi geleneği-şiddet ilişkisi Tanah bağlamında incelenmiştir. Tanah literatüründe yer alan şiddete yönelik mesajların analiz edilmesi hem Yahudi geleneği-şiddet ilişkisinin açıklığa kavuşturulması açısından hem de İsrail-Filistin çatışmasının dayandığı zeminin tespit edilmesi açısından önem arz etmektedir. Zira yaklaşık bin sekiz yüz yıldır pasifist olarak tanımlanan Yahudi kimliği, Siyonist ideolojinin ortaya çıkmasıyla militarist bir niteliğe bürünmüş, binlerce yıldır devam eden apokaliptik beklentiler yerini büyük oranda onarıcı/aktivist mesihçi anlayışa bırakmıştır. Bu süreçte, Siyonist ideolojinin kurucularının ve destekçilerinin seküler dünya görüşüne sahip olmalarına rağmen toprak üzerindeki iddialarını desteklemek için Tanah’a başvurmaları, bu literatürde yer alan seçilmiş ırk inancı ve vaad edilmiş toprak düşüncesi temalarının araçsal kullanımını gündeme getirmiştir.
The effect of firms’ entrepreneurial orientation on innovation performance through business process innovation
Authors:   Korean Academy for Leaders of Management, Kim Baegun , Park Jihoon , Kim Jaemoon
Published: October 2024

The manufacturing sector in Korea had a more severe fall in labor productivity during the global financial crisis than most OECD countries. As a result, the manufacturing sector in Korea is in danger of becoming less competitive. Additionally, due to the Fourth Industrial Revolution and the advancement of intelligent technology, several forms of corporate innovation are becoming more significant. The assessment is that, in light of the alterations in the external milieu and the circumstances confronting the Korean manufacturing sector, domestic manufacturing enterprises must fortify their entrepreneurial orientation and enhance their capacity for innovation to augment the efficacy of their innovation endeavors. As a result, this study looked at the relationship between entrepreneurial orientation and product innovation and considered business process innovation as a multifaceted innovation skill. This study's empirical testing used the Science and Technology Policy Institute's 2020 Korean Innovation Survey data on manufacturing industries. It was discovered that, as a result of business process innovation, entrepreneurial attitude positively impacted product innovation. Furthermore, incremental product innovation was positively impacted by entrepreneurial attitude, whereas radical product innovation was negatively impacted.
Self, Society, and the Passions: Reading Late Eighteenth-Century British Women’s Plays
Authors:   , Hilton Rose Mary
Published: October 2024

This thesis argues for a connection between later eighteenth-century women’s literary dramaturgy and medical and philosophical writing on the topics of self and sociality, in ways that have yet to receive sufficient critical attention. This thesis features close readings of eight play texts written by four female playwrights of the eighteenth century: Joanna Baillie, Elizabeth Griffith, Elizabeth Inchbald, and Hannah More. This research sits at an intersection between literary, dramatic, medical, and philosophical writing as I place the works of the female dramatists examined here in contrast and conversation with the male-dominated fields of medicine and philosophy, and it is through a close reading of various texts that this work investigates the non-linear relationship between theories of self in each field. While critical interest in eighteenth-century female playwrights has increased since the 1980s, attention to male authors and playwrights from this period remains significantly higher, affecting the ways in which women of this period are positioned in relation to perceived ‘male’ fields of knowledge. This thesis demonstrates an original contribution to studies of eighteenth-century drama by focusing on these connections in literary analyses of these plays, building on scholarship that provides the groundwork for the historical and biographical contexts for these dramatists and eighteenth-century theatre more broadly. The hybrid space of the theatre and the very different discursive space of the dramatic text afforded women a unique opportunity to engage with and participate in public discussions about the self and society. Drawing on a keen awareness of their contemporary moments and a clear interest in both philosophical concepts and social questions of ‘performance’, these texts offer a negotiation between philosophy, medicine, and popular discourse. I argue that eighteenth-century British female playwrights were active participants in the social examination and (re)conceptualisation of the self that was also taking place in other fields and that their works are deserving of greater critical attention, particularly using the framework that I showcase in this thesis. In analysing these plays I demonstrate that the self and ideas of social behaviour and performance were central to the writing of dramatists, philosophers, and physicians in the eighteenth century, and I argue that close readings of these plays illuminate how these women were engaging in public discourse on the self. This study, therefore, contributes to the critical re-positioning of women in literary and dramatic studies particularly on the history of the self.
Permissive and instructive Hox codes govern limb positioning
Authors: Wang Yajun , Hintze Maik , Wang Jinbao , Petzsch Patrick , Köhrer Karl , Tao Hengxun , Cheng Longfei , Zhou Peng , Wang Jianlin , Liao Zhaofu , Qi Xufeng , Cai Dongqing , Bartolomaeus Thomas , Schilling Karl , Wilting Joerg , Kuerten Stefanie , Koentges Georgy , Patel Ketan , Pu Qin , Huang Ruijin
Published: October 2024

The positioning of limbs along the anterior-posterior axis varies widely across vertebrates. The mechanisms controlling this feature remain to be fully understood. For over 30 years, it has been speculated that
Hox
genes play a key role in this process but evidence supporting this hypothesis has been largely indirect. In this study, we employed loss- and gain-of-function
Hox
gene variants in chick embryos to address this issue. Using this approach, we found that
Hox4/5
genes are necessary but insufficient for forelimb formation. Within the
Hox4/5
expression domain,
Hox6/7
genes are sufficient for reprogramming of neck lateral plate mesoderm to form an ectopic limb bud, thereby inducing forelimb formation anterior to the normal limb field. Our findings demonstrate that the forelimb program depends on the combinatorial actions of these
Hox
genes. We propose that during the evolutionary emergence of the neck,
Hox4/5
provide permissive cues for forelimb formation throughout the neck region, while the final position of the forelimb is determined by the instructive cues of
Hox6/7
in the lateral plate mesoderm.
A host enzyme reduces non-alcoholic fatty liver disease by inactivating intestinal lipopolysaccharide
Authors: Wang Zhiyan , Ojogun Nore , Liu Yiling , Gan Lu , Xiao Zeling , Feng Jintao , Jiang Wei , Chen Yeying , Zou Benkun , Yu Cheng-Yun , Li Changshun , Ashuo Asha , Li Xiaobo , Fu Mingsheng , Wu Jian , Chu Yiwei , Munford Robert , Lu Mingfang
Published: October 2024

The incidence of Non-alcoholic Fatty Liver Disease (NAFLD) has been increasing world-wide. Since gut-derived bacterial lipopolysaccharides (LPS) can travel via the portal vein to the liver and play an important role in producing hepatic pathology, it seemed possible that (1) LPS stimulates hepatic cells to accumulate lipid, and (2) inactivating LPS can be preventive. Acyloxyacyl hydrolase (AOAH), the eukaryotic lipase that inactivates LPS and oxidized phospholipids, is produced in the intestine, liver, and other organs. We fed mice either normal chow or a high-fat diet for 28 weeks and found that

Aoah
−/−

mice accumulated more hepatic lipid than did

Aoah
+/+

mice. In young mice, before increased hepatic fat accumulation was observed,

Aoah
−/−

mouse livers increased their abundance of Sterol Regulatory Element-Binding Protein 1 (SREBP1) and the expression of its target genes that promote fatty acid synthesis.

Aoah
−/−

mice also increased hepatic expression of CD36 and Fabp3, which mediate fatty acid uptake, and decreased expression of fatty acid-oxidation-related genes Acot2 and Ppar-α. Our results provide evidence that increasing AOAH abundance in the gut, bloodstream and/or liver may be an effective strategy for preventing or treating NAFLD.
Robust optogenetic inhibition with red-light-sensitive anion-conducting channelrhodopsins
Authors: Oppermann Johannes , Rozenberg Andrey , Fabrin Thomaz , González-Cabrera Cristian , Parker Rafael , Béjà Oded , Prigge Matthias , Hegemann Peter
Published: October 2024

Channelrhodopsins (ChRs) are light-gated ion channels widely used to optically activate or silence selected electrogenic cells, such as individual brain neurons. Here, we describe identifying and characterizing a set of anion-conducting ChRs (ACRs) from diverse taxa and representing various branches of the ChR phylogenetic tree. The Mantoniella squamata ACR (MsACR1) showed high sensitivity to yellow-green light (λmax at 555 nm) and was further engineered for optogenetic applications. A single amino-acid substitution that mimicked red-light-sensitive rhodopsins like Chrimson shifted the photosensitivity 20 nm toward red light and accelerated photocurrent kinetics. Hence, it was named red and accelerated ACR, raACR. Both wild-type and mutant are capable optical silencers at low light intensities in mouse neurons in vitro and in vivo, while raACR offers a higher temporal resolution.
Optimization of ultrasonic-assisted debittering of Ganoderma lucidum using response surface methodology, characterization, and evaluation of antioxidant activity
Authors: Chen Shuting , Song Shiying , Tan Yumei , He Shengling , Ren Xiyi , Li Zhu , Liu Yongxiang
Published: October 2024

Background

Ganoderma lucidum (G. lucidum) has gained increasing attention as a potential health care product and food source. However, the bitter taste of G. lucidum has limited its development and utilization for the food industry.

Methonds

The response surface methodology was employed to optimize the inclusion conditions for the debittering of G. lucidum. The effects of 2-hydroxypropyl-β-cyclodextrin concentration (12–14 g/mL), ultrasound temperature (20–40 °C and host—guest ratio (1:1–2:1) on response variables were studied. The physical characteristics of inclusion complexes prepared through spray drying and freeze drying were analyzed. The antioxidant activity of the different treated samples was subsequently investigated.

Results

Study results showed that, in comparison to the control group, the inclusion solution displayed a significantly enhanced taste profile under optimal processing conditions, exhibiting an 80.74% reduction in bitterness value. Fourier transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance (NMR) studies indicated the successful formation of inclusion compounds. The moisture content and bulk density of spray-dried powder were found to be significantly superior to those of freeze-dried powder (p < 0.05). In comparison to the diluted solution, the inclusion liquid demonstrated a 20.27%, 30.01% and 36.55% increase in ferric ion reducing antioxidant power (FRAP), hydroxyl radical scavenging and 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) scavenging respectively. Further, the DPPH clearance of microencapsulated powder was not significantly different from that of tocopherol at a concentration of 25 mg/mL.

Conclusions

In summary, the study provides theoretical basis and methodological guidance to eliminate the bitterness of G. lucidum, and therefore provide potential options to the use of G. lucidum as a food source.
The effects of resistance training to near volitional failure on motor unit recruitment during neuromuscular fatigue
Authors: Beausejour Jonathan P. , Knowles Kevan S. , Pagan Jason I. , Rodriguez Juan P. , Sheldon Daniel , Ruple Bradley A. , Plotkin Daniel L. , Smith Morgan A. , Godwin Joshua S. , Sexton Casey L. , McIntosh Mason C. , Kontos Nicholas J. , Libardi Cleiton A. , Young Kaelin , Roberts Michael D. , Stock Matt S.
Published: October 2024

Background

It is unclear whether chronically training close to volitional failure influences motor unit recruitment strategies during fatigue.

Purpose

We compared resistance training to near volitional failure vs. non-failure on individual motor unit action potential amplitude (MUAP) and surface electromyographic excitation (sEMG) during fatiguing contractions.

Methods

Nineteen resistance-trained adults (11 males, 8 females) underwent 5 weeks (3×/week) of either low repetitions-in-reserve (RIR; 0–1 RIR) or high RIR training (4–6 RIR). Before and after the intervention, participants performed isometric contractions of the knee extensors at 30% of maximal peak torque until exhaustion while vastus lateralis sEMG signals were recorded and later decomposed. MUAP and sEMG excitation for the vastus lateralis were quantified at the beginning, middle, and end of the fatigue assessment.

Results

Both training groups improved time-to-task failure (mean change = 43.3 s, 24.0%), with no significant differences between low and high RIR training groups (low RIR = 28.7%, high RIR = 19.4%). Our fatigue assessment revealed reduced isometric torque steadiness and increased MUAP amplitude and sEMG excitation during the fatiguing task, but these changes were consistent between groups.

Conclusion

Both low and high RIR training improved time-to-task failure, but resulted in comparable motor unit recruitment during fatiguing contractions. Our findings indicate that both low and high RIR training can be used to enhance fatiguability among previously resistance-trained adults.