bluuebunny/crossref_metadata_2025 huggingface dataset:
Chronic obstructive pulmonary disease and miocardial revascularisation outcomes: relationship with self-reported quality of life
Authors: Kamenskaya O. V. , Loginova I. Yu. , Klinkova A. S. , Porotnikova S. S. , Lomivorotov V. N. , Lomivorotov V. V. , Cherniavsky A. M.
Published: December 2022

Aim. To assess the impact of chronic obstructive pulmonary disease (COPD) on the outcomes of myocardial revascularisation and the self-reported quality of life (QoL) during long-term follow-up. Methods. This prospective cohort study included 454 consecutive patients who underwent scheduled myocardial revascularisation. The follow-up continued for 3 years after the surgery. All patients underwent pulmonary functional tests before the surgery. The diagnosis of COPD was verified according to the Global Initiative for Obstructive Lung Disease criteria. QoL assessment was performed before and 3 years after the surgery using the 36-Item Short-Form Health Survey (SF-36). Results. In the study group, the diagnosis of COPD was verified in 14.5% of cases. The mortality rate was 5%, and was significantly higher in patients with COPD. The baseline QoL level was reduced in all patients, regardless of the presence of COPD, with an average of 50 points both in the physical and mental health scores of the SF-36 questionnaire. COPD had a significant negative impact on the QoL physical health score after myocardial revascularisation (odds ratio (OR) 0.95 (0.91 - 0.99), p = 0.043). The forced expiratory volume in the first second (OR 1.02 (1.00 - 1.07), p = 0.048) and new-onset atrial fibrillation in the early postoperative period (OR 0.54 (0.33 - 0.88), p = 0,036) were predictors of lack of QoL improvement. COPD did not correlate with the changes in the psychoemotional component of QoL. Conclusion. COPD has an independent negative impact on the clinical outcomes of myocardial revascularisation, including survival and health-related QoL (physical health score). Thereby, preoperative assessment of the respiratory function is important in these patients.
The upper respiratory tract microbiome and its role in human health: barrier function
Authors: Starikova E. V. , Galeeva Yu. S. , Il’ina E. N.
Published: December 2022

The human respiratory tract is a complex system characterized by a series of niches colonized with specific microbial communities. Until recently, researchers were mostly interested in lung microbiomes associated with acute and chronic infections. The upper respiratory tract microbiota has gained attention during COVID-19 (COronaVIrus Disease 2019) pandemic because it was suspected to influence the course and the outcome of viral infections. Aim. In this two-part review (see part 1, Pul’monolog;iya. 2022; 32 (5): 745-754), we summarize current knowledge of the microbial communities at each upper respiratory tract location, considering the proposed barrier function of the respiratory microbiome. Conclusion. Based on the evidence presented in this review, we can see how the respiratory microbiome is involved in the pathogenesis of viral respiratory infections, including SARS-CoV-2 (Severe Acute Respiratory Syndrome CoronaVirus 2).
Bilateral diaphragm paralysis: a clinical case
Authors: Uryasev O. M. , Zhukova L. A. , Glotov S. I. , Alekseyeva E. A. , Ponomareva I. B. , Almazova E. V.
Published: December 2022

Diaphragm dysfunction is a rare cause of respiratory distress with a variety of clinical manifestations that complicate diagnosis and treatment. The given clinical case demonstrates the possibility of detecting bilateral diaphragm paralysis using available general clinical and instrumental diagnostic methods. Among the physical data, high standing of the lower borders of the lungs with limited mobility and paradoxical movement of the diaphragm during the Mueller test have a high diagnostic value. Chest X-ray demonstrates the high standing of both domes of the diaphragm and subsegmental atelectasis in the basal parts of the lungs. Severe hypoxemia developed: oxygen saturation in clino- and orthostasis was 72 and 96%, respectively. The tests of pulmonary function showed significant restrictive impairments, a decrease in the vital capacity of the lungs was also determined. Ultrasound examination of the diaphragm revealed hyperechogenicity, lack of inspiratory thickening, and respiratory mobility of the domes of the diaphragm. Electromyography confirmed gross right and left phrenic nerve axonopathy. An idiopathic variant of diaphragm dysfunction can be assumed based on the patient stabilization during CPAP therapy, physiotherapy exercises, chest massage, followed by the disappearance of signs of bilateral diaphragm paralysis. Conclusion. The presented case demonstrates the difficulties of diagnosing bilateral diaphragm paralysis. The final diagnosis was made through the use of specific research methods recommended for suspected diaphragm dysfunction. The prognosis of the idiopathic variant of bilateral diaphragm paralysis, as in this case, is favorable. Spontaneous remission was observed.
Diálogos sobre el morir en tiempos de pandemia
Authors: Luque-Núñez Ricardo
Published: December 2022

Propósito/Contexto. Este texto introduce una reflexión sobre temas como la muerte, la pandemia y cómo, desde la simbiosis entre salud pública y Bioética, se puede evitar que el drama sea mayor en este tipo de situaciones.
Metodología/Enfoque. Se realiza una reflexión personal y se establecen como ejes temáticos los cuidados paliativos, el duelo y la salud pública, para conversar con tres investigadores sobre su visión de la pandemia por COVID-19.
Discusión/Conclusiones/Contribuciones. La conversación con tres expertos nos da una perspectiva sobre cómo, en medio de una pandemia, se pueden tomar acciones en las que prevalezcan, por encima de intereses económicos, la solidaridad y la búsqueda de las mejores condiciones de salud y apoyo social para los más vulnerables.
Biomass Assessment of Peach Trees in the Ecuadorian Andes
Authors: Velázquez-Martí Borja , Vega Chariguaman Jorge Efraín , Gutiérrez Albán Alberto Cristobal , Cazco-Logroño Carlos , Chandi Mora Henry Rolando
Published: December 2022

This work focused on the evaluation of four essential aspects of biomass based on peach trees grown in the Andean region of Ecuador. In one case, mathematical models have been developed allowing the amount of lignocellulosic material to be quantified from easily measurable parameters such as crown diameter, stem diameter and plant height. Performing quick surveys, these equations led to obtain the amount of biomass contained in a plot. In a second case, elemental analysis of biomass was performed in order to determine the amount of CO2 captured from the atmosphere through photosynthesis during its growth, and thus to assess the contribution of these plots in mitigating climate change. Afterwards, residual biomass from pruning was quantified and a proximal analysis was carried out. This allowed us to assess the suitability of these materials as solid biofuels. The models obtained to determine the volume of the branches gave determination coefficients of 0.98. Models to quantify the biomass of the whole plant had r2 of 70%. The density of the dried material was 0.92 g/cm3, obtaining an average dry wood weight of 44.8 kg per plant. This represents a content of 1682 moles of captured CO2 of a developed plant crop (3 years). The average ash on dry wood was 3%, fixed carbon content on dry wood was 7%, and volatile content dry wood was 78%. The moisture content of waste materials after pruning was 45.96%. The drying time in store for humidity below 10%, suitable for burning boiler, was 15 days. The higher heating value of peach wood was 18.92MJ/kg.
Hospitalismo
Authors: Escardó Florencio , Giberti Eva
Published: December 2022

Este libro, publicado en 1964, constituye una pieza histórica, que problematiza las consecuencias de la internación hospitalaria en la infancia, y la importancia de la teoría del apego, discusiones iniciadas en el debate internacional por René Spitz y John Bowlby. Eran tiempos que, en general, la internación distaba mucho de ser una práctica humanizada. Durante la primera mitad del siglo XX se dio una importante discusión sobre las consecuencias de la internación prolongada en la niñez y la separación de la madre de su hija o hijo. Este libro recoge esos antecedentes desde las primeras décadas del siglo XX en países de distintos continentes, con posiciones a favor y en contra de la internación conjunta. Escardó y Giberti aportan una rica discusión sobre la importancia de la internación conjunta de la madre con su hijo o hija, postulando la unidad psicofísica en la niñez y poniéndola en práctica en el Hospital de Niños Ricardo Gutiérrez. Jorge Arakaki, Hugo Spinelli Fragmentos del Prólogo
Reimplantation of Tooth after Avulsion - A Case Report
Authors: Yadav Madhukar , Gupta Sonal , Dutta Shilpi
Published: December 2022

An avulsion is the most common of all dental injuries in a pediatric patient. Its prognosis depends on time management and a proper treatment plan. The most favoured treatment of choice after avulsion is reimplantation, but cannot always be carried out immediately. A case of reimplantation of maxillary central incisors which got accidentally avulsed in a 14-yearold boy is reported. The teeth were reimplanted back into the alveolar socket and splinting with 23 gauge stainless steel wire and composite was performed. Follow-up at 7 and 15 months of the interval was done. After 15 months of follow-up, no symptoms of pain or mobility of the teeth were seen. The reimplanted teeth were firm and there was no sign of infection, inflammation or resorption radiographically.
Correlation between BOD/COD Ratio and Octanol/Water Partition Coefficient for Mixture Organic Compounds
Authors: Al-Rosyid Latifa Mirzatika , Santoso Irwan Bagyo , Titah Harmin Sulistiyaning , Mangkoedihardjo Sarwoko , Trihadiningrum Yulinah , Hidayati Dewi
Published: December 2022

Correlation between the BOD/COD ratio and Partition coefficient of octanol/ water (Pow) on a single organic substance shows that the Pow value is directly proportional to the toxicity level and inversely proportional to BOD/COD ratio. This research examined the correlation to a mixture of organic substances. The objective is to obtain a varied range of substances, as well as determining the quality of wastewater discharging to fresh waters. Need for analysis of organic substances used as antiseptics during the Covid-19 pandemic. In addition, organic substances from the organophosphate pesticide class, diazinon, were used. BOD5, COD, Pow, and LC50-96h toxicity tests using Daphnia magna were used. Six types of the mixture of organic substances included diazinon-formaldehyde-isopropyl alcohol, ethanol-oxalic acid-formaldehyde, isopropyl alcohol-glycerol-lactose, acetic acid-isopropyl alcohol-formaldehyde, sucrose-glycerol-acetic acid, and oxalic acid-formaldehyde-diazinon, with 3 different concentrations of 10, 100, and 1000 mg/L, three repetitions. The lowest BOD/COD ratio (<0.2) and the highest Pow value (>4) are found in diazinon-formaldehyde-IPA. Its toxicity in D. magna also showed the lowest LC-50 (11.82 mg/L). Whereas, sucrose-glycerol-acetic acid had the highest BOD/COD ratio (>0.7) and lowest Pow (<0.7) with the highest LC- 50 (567.88 mg/L). Other organic substances mixtures have characteristics in the range of these mixtures. Pow variability and the BOD/COD ratio have a negative correlation. A mixture of organic matter is more biodegradable making it has a higher tendency to dissolve in water.
Newborn Hearing Screening at a Single Tertiary Care Hospital in the United Arab Emirates
Authors: Al Shamisi Ahmed Mohamed , Roy Merry Elizabeth
Published: December 2022

Background and Aim: The United Arab Emirates has been successfully identifying and rehabilitating children having congenital hearing loss. A dearth of published data regarding the newborn hearing screening programs in the country demands the current study. The study aimed to find incidence of hearing loss and impact of known risk factors for hearing loss in a cohort of newborn babies in a single tertiary hospital in the United Arab Emirates.
Methods: A retrospective analysis of hearing screening from January 2010 to December 2019 on a total of 37661 newborn babies were conducted using a screening protocol in auditory brainstem responses.
Results: We report an overall incidence of 0.16% for congenital hearing loss in the current study population. Babies with prolonged stay in Newborn Intensive Care Unit (NICU) had an incidence of 0.87% and in babies with positive family history of hearing loss, it was as high as 2.2%. Chi square analysis revealed the significance of these risk factors (p<0.001). 72% (44.61) received hearing rehabilitation by being fitted with cochlear implants and hearing aids except in few having other comorbidities.
Conclusion: The newborn screening program has run a successful journey since the beginning in the country and the current study is an example. A majority of children identified has received early audiological rehabilitation helping the country in promoting inclusive education and better quality of life for them. Further studies may be implicated to see the outcome of early rehabilitation initiated in the identified population.
Keywords: Hearing loss; newborn screening; newborn intensive care unit; family history; risk factors
The Effectiveness of Mindfulness-Based Cognitive Therapy on Negative Automatic Thought, Psychological Symptoms, Severity of Pain and Quality of Life in Female Patients with Fibromyalgia: A Randomized Controlled Trial
Authors: Shokouhi Nejad Naghmeh , Bayat Mohammadreza , Zangeneh Motlagh Firoozeh
Published: December 2022

The Article Abstract is not available.
Prediction of Quality of Life Using Dermatology Life Quality Index in Iranian Patients with Neurofibromatosis Type 1
Authors: Foji Samira , Sanagoo Akram , Sharif Nia Seyed Hamid , Jouybari Leila
Published: December 2022

Background: Neurofibromatosis type 1 (NF1), a genetic condition most commonly characterized by the presence of dermal neurofibromas and café au lait macules, has a significant impact upon the Quality of Life (QoL). The purpose of this study is to predict the QoL with Dermatology Life Quality Index (DLQI) in Iranian patients with neurofibromatosis type  .1
Methods: This cross-sectional study was conducted on 223 patients with neurofibromatosis type 1 using available sampling. Data collection tools were demographic information form, SF-36 and DLQI questionnaires. Quality of life was predicted by DLQI. Linear and multiple regression tests were utilized to analyze the data.
Results:  Predicting the quality of life by dermatology quality of life showed that the physical function by the variable “work and school” and treatment, role limitations due to physical health by the variable of work and school, the role limitations due to emotional problems by the variable of treatment, emotional well-being by the variable of interpersonal relationships, pain by the variable of symptoms and feelings, daily activities, and personal relationships were predictable. Finally, social function, general health and fatigue cannot be predicted by any variable.
Conclusion: The results of this study indicated that the quality of dermatology life is able to predict some aspects of quality of life. These findings can be used to provide better health services to this group of patients and improve their quality of life.
Corticosteroid Versus Dextrose Ultrasound-Guided Injection in the Treatment of Sacroiliac Joint Dysfunction: A Randomized Double-Blinded Clinical Trial
Authors: Raissi Gholamreza , Ahadi Tannaz , Forogh Bijan , Moradi Katayoun , Madani Seyed Pezhman , Yousefi Naseh , Foroumadi Roham , Rahimi-Dehgolan Shahram
Published: December 2022

Background: Sacroiliac Joint (SIJ) dysfunction, a common etiology of Low Back Pain (LBP), is a challenging diagnosis. There is controversy over the efficacy of prolotherapy and corticosteroid injections in relieving SIJ dysfunction. Inconsistent success rates reported in previous studies can be due to heterogeneity in selecting the patients and procedures between studies. This study was conducted to compare the efficacy of local injection of dextrose prolotherapy and corticosteroid in treating the SIJ dysfunction.
Methods: This 36-week, double-blind, Randomized Controlled Trial (RCT) included 40 patients with SIJ dysfunction. The clinical impression was confirmed by the use of a diagnostic injection of local anesthetic inside SIJ. Participants received a single injection of either hypertonic dextrose solution or triamcinolone under Ultrasound (US) guidance. The primary outcome measurement tools, including the Visual Analog Scale (VAS) for pain and the Dallas Pain Questionnaire (DPQ), were evaluated initially and after 2, 8, and 36 weeks.
Results: In both prolotherapy and corticosteroid groups, VAS significantly declined within 36-weeks of follow-up. However, there was no remarkable difference between the two groups at any follow-up timepoints. Similarly, DPQ revealed a remarkable improvement in the corticosteroid group while it did not show any meaningful change in the prolotherapy group.
Conclusion: Both local injections of dextrose and corticosteroids can successfully reduce pain in patients with SIJ dysfunction without significant superiority between the two treatments. However, corticosteroid injection was slightly more effective in terms of improvement of functional status. Further investigations are required to extend these results to SIJ dysfunction treatment more reliably.
Clinimetric Properties of the Persian Handwriting Assessment Tool as a Screening Tool for Children with Specific Learning Disorder
Authors: Meimandi Mahsa , Azad Akram , Havaei Naser , Zareiyan Armin
Published: December 2022

Background: The Persian Handwriting Assessment Tool (PHAT) evaluates speed and legibility in copying and dictation domains. The aim of the present study was to determine psychometric validation and diagnostic accuracy features of the PHAT for students with specific learning disorder.
Methods: In this cross-sectional study, handwriting of 120 participants (typically developing students, N= 60; students with specific learning disorder, N= 60; mean age (SD): 9.23 ± 0.53 years and 9.13±0.56 years, respectively) were assessed with PHAT. Receiver Operating Characteristics (ROC) curve analysis was carried out to derive validity parameters and Area Under the Curve (AUC) for diagnostic accuracy. Discriminative validity, internal consistency, test-retest reliability and absolute reliability were examined.
Results: The PHAT had significant ability to discriminate typically developing students from students with specific learning disorder in formation, spacing and alignment (AUC= 0.78-0.95) and moderate accuracy (AUC= 0.61-0.66) in text slant in both domains. Acceptable discriminative validity (P< 0.01), internal consistency (copying: α= 0.80-0.98; dictation: α= 0.83-0.98), and test-retest reliability (copying: ICC2,1= 0.75-0.98; dictation: ICC2,1= 0.78-0.98) were also obtained.
Conclusion: The current study suggests that the PHAT has satisfactory reliability, validity and high to acceptable diagnostic accuracy for students with specific learning disorder.
Molla Sadrâ’nın İdealar İspatlaması
Authors: YİĞİT Fevzi
Published: December 2022

Bu makalede Molla Sadrâ’nın idealar ispatlaması -onun Fârâbî, İbn Sînâ ve Sühreverdî’nin görüşleri hakkındaki değerlendirmeleri de esas alınarak- konu edilmiştir. Makalenin amacı Sadrâ’nın yapmaya çalıştığı ispatlama hakkında belirli bir kanaatin oluşmasını sağlamaya çalışmaktır. Sadrâ’nın genel olarak idealar hakkında ikili bir tavır sergilediği görülür. Sadrâ’nın birinci tavrı kelamcıların isimler öğretisini, Sühreverdî’nin türlerin efendisi görüşünü, tasavvufçuların a’yân-ı sâbite teorisini ve Meşşâîlerin türsel küllî anlayışını idealar ile eşleştirmektir. Onun ikinci tavrı, Eflâtun’u anlama ve meselenin künhüne erme noktasında yalnız kaldığı yönündedir. Başka bir ifadeyle o, kendisine kadar meseleyi olması gerektiği biçimde anlayan ve anlatan birisinin olmadığını dile getirir. Sadrâ konuyla ilgili kendi başarısını hem keşif ve ilhama hem de varlık merkezli aklî araştırmalarına bağlar. Sadrâ’nın amacı Eflâtun ve Aristoteles arasını birleştirmeye çalışmaktır. Dolayısıyla o, kendisinden önce bu amaca sahip olan Plotinos ve Fârâbî’yi de takip eder. Konuyla ilgili olarak İbn Sînâ’yı eleştiren Sadrâ, doğruya en yaklaşan filozof olarak Sühreverdî’yi görür ancak onun da bazı noktalarda yetersiz kaldığını dile getirir.
A necessidade de assistência ao cuidador familiar do paciente com Doença de Alzheimer
Authors: Zuehl Dal Toé Helena Cristina , Rosa Pacheco Tamires , Andrade Quadros Luiz Felipe , Vicente Bavaresco Daniela , Budni Josiane , Tuon Talita , Da Silva Valvassori Samira , Marlaine Xavier Kuerten Claudia
Published: December 2022

A Doença de Alzheimer (DA), é um tipo de demência progressiva, que se agrava ao longo do tempo, apresentando perda das funções cognitivas, reduzindo assim a capacidade do indivíduo no trabalho e nas relações sociais de forma gradativa. O acompanhamento de um idoso com DA produz desgaste psicológico, físico e financeiro para o cuidador, pois o tratamento é dispendioso e o paciente irá evoluir para um quadro de total dependência. Nos casos em que o cuidador também é membro familiar questões emocionais e psicológicas mais complexas e fortes são somadas. Entender essa realidade é o ponto de partida para melhorar as condições do cuidador familiar. Percebeu-se a importância de enfatizar a necessidade de uma assistência ao membro familiar e cuidador do indivíduo com DA.
Fidelização de clientes no laboratório de análises clínicas: uma revisão bibliográfica sobre as inovações na prestação de serviço em saúde
Authors: Steckert da Silva Candice , Borba Vefago Raupp Cristiani
Published: December 2022

O presente estudo tem como plano de fundo a explicitação da globalização e do aumento crescente da competitividade nos mercados, trazendo à tona a necessidade constante atuação das empresas pelas melhores práticas organizacionais, tendo em vista a manutenção de competitividade sustentável de longo prazo. Esta pesquisa visou analisar abordagens da literatura relacionadas a inovação para fidelização de clientes no laboratório de análises clínicas, e para isso fez uma explanação sobre as iniciativas de padronização que buscam a promoção da melhoria da qualidade no âmbito dos serviços de saúde; debatendo os conceitos e a aplicabilidade da inovação e discutindo como a inovação pode agregar valor aos serviços no laboratório clinico que pretende fidelizar seus clientes. Trata-se de uma pesquisa qualitativa, que se utilizou do estudo bibliográfico como forma de coleta e análise de dados. As contribuições geradas a partir da literatura compreendem a inovação como fator de grande relevância para a construção de uma vantagem competitiva para a fidelização de clientes
CAPSULITE ADESIVA DE OMBRO UMA REVISÃO: INTERVENÇÕES FISIOTERAPÊUTICAS ISOLADAS OU ASSOCIADAS AO BLOQUEIO ANESTÉSICO
Authors: Longen Willians Cassiano , De Assis do Canto Daiana , Honorato da Luz Morgana
Published: December 2022

A capsulite adesiva de ombro (CAO) é caracterizada por dor crônica espontânea e perda funcional do movimento. Um dos principais tratamentos para CAO é a terapia conservadora que inclui exercícios de Fisioterapia e analgesia. O Objetivo desta revisão sistemática foi descrever a evolução do tratamento da CAO utilizando Fisioterapia isolada ou associada à técnica de bloqueio anestésico. Os resultados demonstram que ambos os tratamentos para CAO, tanto os fisioterapêuticos como o bloqueio anestésico possuem evidencias a favor ou contra. O estudo sugere que a Fisioterapia convencional, utilizando exercícios passivos e ativos combinados, pode ser considerada como estratégia importante no manejo conservador da CAO. Em casos adversos, o uso associado do bloqueio anestésico pode ajudar no tratamento.Palavras-chave: Dor Crônica; Ombro; Analgesia; Fisioterapia.
O uso de antidepressivos na gestação
Authors: Dotto Bethina Segabinazzi , Dal Bó Silvia
Published: December 2022

A depressão está diretamente relacionada com quadros de alterações psicopatológicas diversas, porém diferenciam-se consideravelmente em relação à sintomatologia, gravidade, curso e prognóstico. O aparecimento e a presença de transtornos psiquiátricos no período reprodutivo são comuns em mulheres e seu tratamento no ciclo gestacional é complexo, necessitando tomada de decisões clínicas difíceis. Sabe-se também que o período perinatal é desencadeador ou reativador de quadros depressivos assim como a depressão pós-parto que se inicia durante a gestação e não é reconhecida. O acompanhamento do obstetra durante o pré-natal é essencial para o reconhecimento de sintomas que permitam intervenções precoces e para prevenção dos quadros mais graves. Apesar da morbidade associada às doenças psiquiátricas, existe uma prevalência em se evitar o uso de psicofármacos durante a gestação. Diante disso, este trabalho objetivou por meio de revisão de artigos e a análise dos dados, procurar evidenciar os riscos e benefícios do uso de antidepressivos no período gestacional, bem como de alguma forma, procurar identificar os mais indicados para uso nesse período. Palavras chaves: depressão, antidepressivo, gravidez.
Evaluation of intravarietal polymorphism of tomato fungal disease resistance genes in Michurinsky State Agrarian University breeding varieties
Authors: Shamshin I. N. , Ilyichev A. S. , Grosheva E. V.
Published: December 2022

Relevance. The studies are aimed at assessing the intravarietal allelic diversity of genes for resistance to fusariosis and cladosporiosis of tomato cultivars bred at the Michurinsky State Agrarian University using molecular markers.

Methods. The biological objects of the study are tomato varieties bred at the Michurinsky State Agrarian University. A total of 10 varieties were analyzed. The assessment of intravarietal polymorphism was determined on a sample of 10 plants of each variety. DNA extraction was performed using a Quick-DNA Plant/Seed Miniprep Kit (Zymo Research, USA) for DNA extraction according to the manufacturer's protocol. The P7 DNA marker was used to identify the cladosporosis resistance gene Cf-19. The presence of the fusarium wilt resistance gene I-2 was determined using the marker I-2/5. Amplification results were visualized by electrophoresis in 2% agarose gel.

Results. 10 plants of 10 varieties of Michurinsky GAU selection tomato were analyzed using molecular markers of genes for resistance to cladosporiosis and fusariosis. An assessment of intravarietal polymorphism was carried out. In most of the varieties studied, the genes analyzed are identified in a heterozygous state. Three varieties (Vivat, Carotinka, Krasavets) containing only alleles of susceptibility to the causative agent of the disease in the genotype I-2 identified by the gene. Individual samples were homozygous for the fusariosis resistance allele. Analysis of the gene for Cf-19 resistance to cladosporiosis showed that most of the varieties studied are heterozygous forms. In some varieties, all ten plants were heterozygous. These include Krasavets, Vivat, Orlik, Bui Tour. The remaining samples had different allelic compositions. The pathogen resistance allele has been identified in plants of the Nepryadva and Chernysh varieties. The dominant allele in the homozygous state was detected in the Japanese variety. At the same time, all the analyzed plants of this variety were monotonous.

Conclusion. It has been established, but a significant part of the varieties of tomato selection of Michurinsky GAU is polymorphic in the genes for resistance to cladosporiosis and fusariosis. In this case, a significant part of the varieties can be used in selection during preliminary molecular analysis. According to the gene for resistance to fusariosis, the following varieties are identified sources of the resistance allele: Sokol, Nepryadva, Yaponchik, Orlik, Zolotnichok, Chernysh. In them, the gene is I-2 represented in a heterozygous state. Intraortic polymorphism was also noted for the Cf-19 gene. Most samples have two alleles. The exception is the Japanese variety, which is the dominant homozygote for this gene.
Precision farming technologies in vegetable growing
Authors: Fedosov A. Yu. , Menshikh A. M.
Published: December 2022

Precision farming technologies can help mitigate the environmental impact of agriculture by reducing the use of fertilizers and irrigation while reducing costs. Vegetable precision farming technology uses geographic positioning system (GPS), geographic information system (GIS), artificial intelligence (IoT), robotics, sensor technology, data-based genome editing, etc. to improve the production and quality of vegetables. Digital genome sequencing, developed over the past decade, has greatly reduced the cost and time required to map the DNA of plants and other organisms. Digital genome sequencing methods generate vast amounts of genome sequence data, which in turn aid in plant breeding for specific field conditions or desired traits. This maintains excellent prospects for growing vegetables in the current farming scenario, when climate change is forcing a rethink of all agricultural practices. This article provides useful information about precision farming technologies for vegetable growers, enthusiasts, farmers and researchers. Economic factors are important drivers and barriers to technology adoption. The practical significance of new technologies provided through communication and education has additional potential in terms of their promotion.
Spotlights: Faculty, Alum, Kaigler Children's Book Festival
Authors: Creel Stacy
Published: December 2022

Meet Dr. Brendan Fay, new Associate Director, and alumni Kristen Hillman, and get insights on the Fay B. Kaigler 2023 Children's Book Festival.
A Bibliometric Study of the Research on Instructional Uses for Nonfiction Graphic Novels
Authors: Markulike Tiffany
Published: December 2022

The intention of this bibliometric study is to examine the research on the use of graphic novels in classrooms and libraries during the past two decades to highlight how this topic has changed and developed over time. The focus of the research is on the use of nonfiction graphic novels in the English Language Arts, Writing, Social Studies, History, Science, and Math classrooms. This study notes similarities in the research on uses for graphic novels and identifies the prevailing journals which have published articles on this topic. The authors who have written about this topic the most frequently are identified. This study also provides a list of some highly recommended nonfiction graphic novels cited in the research by authors for classroom use.
​Optimization of Sowing Density for Improving Fruit Yield of Tomatoes Grown in Open-field Crop
Authors: Dinh Kim Hao Thi , Dang Truong An
Published: December 2022

Background: Sowing density optimal is rated a less expensive solution for enhancing the output of tomato yield in the background of extending food requirements worldwide. Methods: The main objective of this study is to investigate the sowing density effect on the growth and tomato yield planted in Don Duong district of Lam Dong province, Vietnam. The study was conducted during the spring tomato crop (January to June 2020) with five different sowing densities varying from 33000 to 50000 plants/ha based on drip irrigation system supply approximately 100% of actual evapotranspiration. Result: Results pointed out that among investigated sowing densities, sowing density 45830 plants/ha obtained the optimal fruit yield (OFY) up to 87.8 tons/ha compared with different sowing densities while other observed variations as the number of bunches, fruit weight per plant and diameter were no significant difference. Based on the findings, tomato growers can sow with a density 45830 plants/ha to obtain the OFY thereby contributing to increase profits.
Estimation of Combining Ability for Yield Traits in Groundnut using Genetic Variance-covariance among Relatives
Authors: Barsalia Ramandeep Kaur , Brar Khushwinder Singh , Singh Pritpal , Sandhu Surinder
Published: December 2022

Background: In standard mating designs, the suitability of a line as a parent is generally assessed by examining its overall genetic effects. However, if the given attributes of a line are due to gene interaction (epistasis), this approach becomes less reliable. As the performance of the line will exceed the sum of alleles, thereby inflating its breeding potential. The current study aimed to partition these genetic effects into additive and non-additive effects and their interaction with the environment for authentic selection of parental line(s) having high additive effects. Methods: In this study, genetic effects of 40 advanced breeding lines (ABLs) of groundnut developed through pedigree method were partitioned into additive and non-additive effects by incorporating the pedigree information into analysis. These effects and their interactions were further modelled by incorporating variance-covariance structures constructed as Kronecker product across sites. Result: The merit of 40 ABLs of groundnut was demarcated based on their breeding values. The differential ranking based on both genetic values and additive effects led to conclude that selection for parents should be preferred on breeding values for high genetic gains.
Capacidades técnicas y educativas del profesorado de establecimientos de Enseñanza Media Técnico Profesional
Authors: Constenla Núñez Jaime , Jara Coatt Pilar , Vera Sagredo Angélica
Published: December 2022

La Educación Media Técnico Profesional (EMTP) en Chile aún no ha logrado ajustar sus programas de estudio para responder a las necesidades del mercado laboral actual. Si bien se ha ofrecido perfeccionamiento a los docentes de la EMTP, no existe un seguimiento y monitoreo para determinar si efectivamente estos esfuerzos han permitido mejorar los aprendizajes propios de esta formación. El propósito del estudio considera tres objetivos de investigación: el primero es analizar las capacidades técnicas y educativas de profesores de establecimientos técnico profesional, el segundo identificar las posibles diferencias respecto a variables sociodemográficas y el tercero examinar las correlaciones existentes entre todas las variables revisadas. El estudio contempló un enfoque cuantitativo no experimental, con un diseño descriptivo correlacional de tipo transversal. La muestra correspondió al tipo no probabilístico por conveniencia intencionada y quedó constituida por 179 docentes de ocho establecimientos de la provincia del Biobío, Chile. En el estudio se examinaron cuatro áreas estratégicas: Gestión pedagógica, Liderazgo escolar, Convivencia y Gestión de recursos. Con la finalidad de cuantificar las dimensiones del instrumento, se realizaron análisis comparativos de diferencias de media, a través de Anova y prueba t, así como correlaciones mediante el coeficiente de Pearson. Los principales resultados dan cuenta que no existirían diferencias estadísticamente significativas respecto a las horas de trabajo de los profesores, pero sí se evidencia diferencia en cuanto al sexo y los años de experiencia. A modo de conclusión, se advierte que los docentes valoran positivamente alguna de las prácticas instauradas en los centros educativos como la enseñanza y aprendizaje en el aula, el liderazgo directivo, la convivencia la gestión de recursos financieros. Sin embargo, existirían dificultades en lo referido a la toma de decisiones que los directivos realizan con base en los resultados obtenidos en evaluaciones internas o externas de su institución educativa. Del mismo modo, se evidenciaron resultados negativos en cuanto a la gestión de recursos educativos para mejorar los procesos de enseñanza y aprendizaje del estudiantado.
Multi-Regression Analysis of Factors Influencing Perceived Academic Writing Competence (PAWC) of Vocational School Students
Authors: Prihandoko Lastika Ary , Ahmad Ana Shohibul Manshur Al , Fredy Fredy , Rahman Fathu
Published: December 2022

Most upper-semester students who fail to graduate have an issue with their perceived academic writing competence (PAWC). PAWC is associated with writing self-efficacy (WSE) and writer's block (WB). Thus, improving WSE and decreasing WB are crucial for succeeding in the final project writing of the upper-semester students. Only limited studies focused on exploring academic writing practice for vocational students by survey strategy. This study used a quantitative approach to test the hypothesis that WSE and WB positively affect PAWC. Respondents were selected using random sampling involving 200 students from a vocational school in Surakarta. Respondents filled survey about PAWC, WSE, and WB consisting of 18 items. The hypothesis was tested by multiple regression analysis. The study results revealed that WSE and WB are positively correlated with PAWC. This research implies that faculty members are advised to focus on encouraging WSE and reducing WB to improve AW competence through curriculum improvements. With the increase in students' academic writing skills, the classic problem of late completion of studies due to late writing of the final project can be solved.
İnsansız Hava Araçları (İHA) ile Arkeolojik Alanlarda Belgeleme: Sarıkaya Roma Hamamı (Therma Basilica) Örneği
Authors: Akın Emine Saka , Erdoğan Alperen
Published: December 2022

Arkeolojik alanlarda belgeleme çalışmaları son yıllarda kullanılan yeni teknikler sayesinde daha kolay, hassas, ekonomik ve kısa sürede yapılmaktadır. Bu çalışmada bu tekniklerden İnsansız Hava Araçları (İHA) Fotogrametrisinin arkeolojik alanlarda belgeleme çalışmalarında kullanılmasının Yersel Lazer Tarama (YLT) tekniğine göre avantajlarının tartışılması amaçlanmıştır. Yozgat İli, Sarıkaya İlçe merkezinde bulunan ve M.S. 1. Yüzyıla dayandırılan Sarıkaya Roma Hamamı çalışmada örnek alan seçilmiştir. İHA ile belgelemeye yönelik kazı alanında uçuş öncesinde araziye Yer Kontrol Noktaları (YKN) işaretlenmiş ve GPS (Global Positioning System) ile koordinatlandırılmıştır. İHA ile elde edilen görüntüler ile çalışma alanının ortofotosu ve nokta bulutu verileri Structure From Motion (SFM) tekniği ile üretilerek Sarıkaya Roma Hamamı’nın Üç Boyutlu (3B) modeli yaklaşık 4 cm. hassasiyetinde üretilmiştir. Bu veriler aynı alanda daha önce YLT tekniği ile yapılan verilerle karşılaştırılmış ve birbirleri ile benzer hassasiyete ulaştığı görülmüştür. Sonuç olarak İHA Fotogrametri tekniğinin arkeolojik alana zarar vermeden kullanılabilmesi, kısa zaman, az uzman gerektirmesi ve daha ekonomik olması YLT tekniğine göre avantajlı yönleridir. Zengin bir kültürel mirasa sahip Türkiye’de pek çok eserin ivedilikle belgelenmesinde İHA Fotogrametri tekniği büyük katkı sağlayacaktır.
AGE-RELATED ADAPTATION OF PORTAL HEMODYNAMICS IN RATS DURING 75 DAY FOLLOW-UP
Authors: Vinogradov Alexander A. , Andreeva Irina V. , Simakova Evgeniya S.
Published: December 2022

The age-related adaptation of portal hemodynamics was studied in young rats by ultrasound methods. In the mode of color Doppler mapping, a color signal was visualized in the projection of the portal vein, and in the spectral Doppler mode, the spectrum of blood flow in the portal vein was visualized. The diameter and cross-section of the portal vein, linear and volumetric blood flow rates were determined. The study was performed at the beginning and after 60- and 75-day follow-up. It was found that the portal hemodynamics parameters were influenced by a change in the diameter of the portal vein. With an increase in the diameter of the portal vein, the linear velocity of blood flow in the portal vein decreased, but the volumetric velocity of blood flow in the portal vein increased. Conclusions. The mechanisms of age-related adaptation of portal hemodynamics include compensation for a decrease in the linear velocity of blood flow by increasing the volumetric velocity of blood flow in the portal vein.
ASSESSMENT OF ANXIOLYTIC POTENTIAL OF NEW С2,С3- QUINOXALINE DERIVATIVES
Authors: Maltsev Dmitry V. , Spasov Alexander A. , Skripka Maria O. , Miroshnikov Mikhail V. , Divaeva Lyudmila N. , Morkovnik Anatoly S. , Zubenko Alexander A. , Klimenko Alexander I.
Published: December 2022

The anxiolytic effect of a new series of C2,C3-quinoxaline derivatives was studied using the "Anxious-phobic state" and "Light/Dark chamber" techniques in comparison with diazepam. It was noted that the presence of a phenyl substituent at the C3 position, which did not contain elements with a distinct electronegativity, as well as 2-methyl-(4,5-dimethoxyphenyl)-N-methylethane-1-amine at the C2 position, had a positive effect on the manifestation of the antianxiety activity of new derivatives of C2,C3-quinoxaline. For the most active compound under the code ZDM-4, the conflict method "Vogel Conflict test" was additionally carried out to confirm the anxiolytic effect of the substance. The tranquiLizing potential of the ZDM-4 compound is of interest for further study.
REVIEW OF RUSSIAN AND INTERNATIONAL CLINICAL GUIDELINES FOR THE MANAGEMENT IN PATIENTS WITH DIABETIC FOOT SYNDROME
Authors: Rogova Natalia V. , Kuzmina Tatiana N.
Published: December 2022

The review presents an analysis of Russian and international clinical guidelines that may guide the doctor in their professional activities in the management of patients with diabetic foot syndrome and its prevention. The purpose of the work is an extended normative support for the decisions made by doctors in the diagnosis and detection of diabetic foot syndrome. Based on the results, an algorithm was developed to support decisions used by doctors in the diagnosis and treatment of patients with diabetic foot syndrome.
PHARMACOLOGISTICS - A NEW PARADIGM IN CLINICAL PHARMACOLOGY
Authors: Petrov Vladimir I.
Published: December 2022

The penetration of business trends in the medical context is sometimes justifiably irritating and frustrating for clinicians. Nevertheless, economic realities demand that the current paradigm of clinical thinking should be supplemented with elements to ensure the rationality of treatment options for patients with various diseases. In these circumstances, the familiar "efficacy-safety" coordinate system is insufficient. The integration of the concept of pharmacologistical paradigm into our medical lexicon is an urgent necessity. We will try to show in a few sentences how reasonable this is, and how it is already present in today's circulation of medications.
DENTAL AND ELEMENTAL STATUS OF ADOLESCENTS LIVING ON THE TERRITORY OF YAMAL
Authors: Oslina Alexandra N. , Nagaeva Marina O. , Koipakov Viktor V.
Published: December 2022

The lack of information on the relationship between the indicators of micro, macronutrient and dental status of adolescents living in Yamal was the basis for analyzing these indicators. A comprehensive dental examination of 112 adolescents aged 12 and 15 years, from among the indigenous peoples living in the territory of the Yamalo-Nenets Autonomous District, an assessment of the actual nutrition and elemental composition of blood serum was carried out. The analysis of the data showed that the prevalence of dental caries among the examined exceeds 99 %. The CPI index ranged from 4,6-7,7. The imbalance of micro- and macroelements involved in ontogenesis and providing the processes of remineralization of hard tooth tissues was revealed. Correction of the elemental status should be included in the complex of therapeutic and preventive measures that increase caries resistance.
CONTRAST-INDUCED NEPHROPATHY: PREVALENCE, DIAGNOSIS, PREVENTION AND TREATMENT
Authors: Petrov V. I , Kudasheva A. A , Frolov D. V
Published: December 2022

Resume. Medical imaging has become an important diagnostic and therapeutic tool in clinical medicine in the era of great technological advances. One of the most frequent and important adverse drug reactions during angiographic studies is contrast-induced nephropathy. Study of epidemiology, risk factors for the development of contrast-induced nephropathy, possible ways of prevention and treatment to reduce the frequency and severity of this complication, improve the quality of patient therapy and reduce the cost of treating complications. Materials and methods. The search for information in the database PubMed, Scopus, Web of Science, e-library, etc. was carried out using the following words and phrases: percutaneous coronary intervention, coronary angiography, contrast-induced nephropathy. Results. The incidence of contrast-induced nephropathy during coronary angiography varies from 2 to 25 %, however, in high-risk groups it can reach 50 %. To prevent the development of contrast-induced nephropathy, there are a number of pharmacological and non-pharmacological approaches. Its prevention is most relevant in high-risk patients. Conclusions. Minimizing the volume of the radiopaque agent, preventing and correcting hypovolemia, preventing the activation of vasoconstriction are the most effective measures to prevent contrast-induced nephropathy.
GENDER FEATURES OF THE AREAS OF ATTACHMENT OF THE ANTERIOR CRUCIATE LIGAMENT TO THE LATERAL FEMORAL CONDYLE FROM THE POSITION OF SURGICAL ANATOMY
Authors: Volodin Ilya V. , Malanin Dmitry A. , Suchilin Ilya A. , Demeshchenko Maxim V. , Zhulikov Alexander L.
Published: December 2022

Injury of the anterior cruciate ligament (ACL) remains the most common cause leading to limited knee function and earlier development of gonarthrosis. The results of ACL repair in male and female patients remain heterogeneous. Women have worse results of surgical treatment, as well as higher risks of ACL injuries (from 1,5 to 10 times) when playing sports. It is assumed that the features of the anatomical structure of the knee play the key role in this joint. We have studied 40 unpaired anatomical preparations of the human knee joint obtained from women and men.The morphometry of the distal femoral epiphysis was performed using a digital sliding caliper according to 16 parameters. When examining the areas of femoral ACL attachment, their shape, size, area, and center distance from individual bone structures were assessed. The data obtained were correlated with the type of structure of the knee joint. Were studied the anatomical features characteristic of the "female" type of structure of the knee joint. It was found that the type of structure of the knee joint affects the topography of the femoral attachment area of the ACL, which must be taken into account in anatomical ligament reconstruction.