bluuebunny/crossref_metadata_2025 huggingface dataset:
Interpretando Modelos de IA en Cáncer de Mama con SHAP y LIME
Authors: Guzmán Ponce Angélica , López-Bautista Joana , Fernandez-Beltran Ruben
Published: July 2024

La Inteligencia Artificial (IA) ha transformado múltiples disciplinas, en concreto en el área médica se ha distinguido por su capacidad de mejorar diagnósticos y tratamientos.  No obstante, la falta de transparencia en los sistemas ha generado desafíos prácticos. La Inteligencia Artificial Explicable (XAI) ha surgido como una solución para abordar estos problemas, permitiendo a los profesionales de la salud comprender y verificar las decisiones de los algoritmos. En este trabajo se aplicarán dos técnicas comúnmente usadas de XAI, específicamente SHapley Additive exPlanations (SHAP) y Local Interpretable Model-Agnostic Explanations (LIME), para interpretar un modelo de red neuronal convolucional usado en el diagnóstico de cáncer de mama a partir de imágenes histológicas del Carcinoma Ductal Invasivo (IDC). Los resultados muestran que ambas técnicas son efectivas para identificar las contribuciones individuales de las características en las predicciones del modelo, resaltando que LIME ofrece una granularidad detallada a nivel de píxel.
Evaluación Sísmica del Tren Interurbano México-Toluca con simulaciones de carga viva y Ciencia de Datos
Authors: Arellano Magdaleno Osmar David , Valdovinos Rosas Rosa Maria , Delgado Hernández David Joaquin
Published: July 2024

El Gobierno Federal de México está construyendo el Tren Interurbano México-Toluca para abordar el desafío de transportar a más de 230 mil personas diariamente entre las ciudades de México y Toluca. Esta construcción comenzó en enero de 2015 y está a cargo de la Secretaría de Comunicaciones y Transportes. Para evaluar la construcción del tren, diversos estudios se han propuesto, de los cuales, la mayoría son realizados a base de simulaciones debido a la poca disposición de datos reales. En este artículo se realiza el análisis del modelo estructural del tren interurbano México-Toluca al ser sometido a un sismo considerando simulaciones ejecutadas con el programa SAP 2000.
El interés en este estudio se centra en identificar la respuesta estructural en caso de un terremoto de magnitud similar al del 22 de mayo de 1960 en Chile y del 19 de septiembre de 1985 en México, mientras el tren se encuentra en movimiento a una velocidad determinada y transportando 711 personas simultáneamente. Para la investigación se utiliza el lenguaje de programación Python y el software libre WEKA siguiendo el proceso general de ciencia y analítica de conglomerados.
Un modelo de Red Bayesiana para datos cualitativos de Vaginosis Bacteriana en mujeres embarazadas
Authors: Bautista Hernández Carlos Mario , Canul Reich Juana
Published: July 2024

La Vaginosis Bacteriana BV es un factor de riesgo para el parto prematuro. La Organización Mundial de la Salud OMS, destaca que a pesar que la BV ya se considera una afección más común y de no tratarse puede provocar problemas en el embarazo como aborto espontáneo y parto prematuro así como mayor riesgo de otras infecciones de transmisión sexual. Las técnicas computacionales de Inteligencia Artificial como Redes Bayesianas Causales CBNs, se han utilizado en diferentes estudios con el objetivo de análisis de diagnóstico de enfermedades. Este estudio tiene la finalidad de compartir como una CBN puede identificar que bacterias coexisten y la relación que tienen frente a un diagnóstivo positivo DxBV+. Los datos que se utilizaron para este estudio tienen como base una recolección de datos reales por parte de personal investigador de la División Académica Multidisplinaria de Comalcalco DAMC formando un dataset de casos positivos, negativos e indeterminados de BV en mujeres embarazadas. El resultado que se obtuvo dio un modelo gráfico causal que es presentado como una CBN y su tabla de probabilidad condicional que detalla el porcentaje de relación con el DxBV+.
ORGANIZATIONAL AND ECONOMIC TRANSFORMATIONS OF THE AGRICULTURAL SECTOR IN THE POST-WAR PERIOD OF ECONOMIC DEVELOPMENT OF UKRAINE
Authors: Shust Olena ,   Bila Tserkva National Agrarian University, Nykonenko Oksana , Czipa Nikolett ,   Bila Tserkva National Agrarian University,   University of Debrecen
Published: July 2024

The agricultural sector in Ukraine plays a pivotal role in the country's socio-economic stability and food security. However, the full-scale war with Russia has significantly impacted this sector, necessitating comprehensive organizational and economic transformations to restore and enhance its functionality in the post-war period. This study aims to propose practical recommendations for the organizational and economic transformations required in the agricultural sector of Ukraine during the post-war economic revival period. The research employs a combination of general scientific methods, including abstract-logical reasoning, monographic and terminological analysis, theoretical generalization, economic and statistical analysis, abstraction, and formalization. These methods facilitate the substantiation of theoretical approaches, formation of conceptual frameworks, identification of development trends, and justification of strategic directions for the agricultural sector's transformation. Despite the crisis induced by the war, the agricultural sector in Ukraine has demonstrated financial stability and adaptability. In 2022, agriculture contributed 8.6% to GDP, though this was a decline from previous years. The sector's share in export structure increased, becoming a crucial source of foreign currency inflows despite logistical challenges. The study identifies structural issues such as over-reliance on low-value-added exports, technological dependencies, and economic vulnerabilities tied to the raw material orientation. Recommendations include diversifying production, enhancing value-added processing, fostering technological advancements, and creating investment funds for structural economic reforms. Further research should explore the long-term impacts of proposed transformations, the role of technological integration in agriculture, and the development of policies that balance agricultural productivity with environmental sustainability. Additionally, investigating the effectiveness of investment funds and economic incentives in achieving structural changes will be critical to ensuring the resilience and growth of Ukraine's agricultural sector.
NAVIGATING THE SOCIAL MEDIA MAZE: ASSESSING THE EVOLVING RELEVANCE OF PUBLIC RELATIONS IN A DIGITAL LANDSCAPE
Authors: Agarwal Vedika ,   CMR University, Narendra Puppala Venkatram ,   CMR University
Published: July 2024

In today's digital age, social media has revolutionized communication, becoming an integral part of daily life. This transformation has profoundly impacted the field of public relations (PR), as organizations now have unprecedented opportunities to connect with audiences through various social media platforms. Understanding how PR professionals can effectively leverage social media is crucial for navigating the complexities of this digital landscape. The aim of this article is to explore and critically evaluate how the advent and proliferation of social media platforms have transformed public relations practices. This study seeks to understand the impact of social media on PR strategies, communication dynamics, and the professional skill set required in the digital age. This study employs a mixed-methods research design to assess the evolving relevance of public relations (PR) in the digital landscape shaped by social media. This article gives a brief understanding of current trends and best practices in integrating social media into PR strategies to provide insights into navigating the social media maze. The evolution of PR in the digital age and the shift towards social media as a primary means of communication, assisted in the understanding of the challenges and opportunities presented by social media for PR professionals, including managing online conversations, engaging with influencers, and measuring the impact of PR efforts. Furthermore, the strategies for effective PR in a digital landscape, include the development of comprehensive social media strategies, engagement with influencers, and monitoring of online conversations. The emphasis is on the importance of staying informed about emerging trends and best practices to successfully navigate the ever-changing social media maze. This article contributes to the understanding of the evolving relevance of PR in a digital landscape dominated by social media. By adopting effective strategies and embracing innovation, PR professionals can navigate the social media maze and build stronger relationships with their audiences in today's dynamic digital environment.
DEMOCRATIZING INDIA: THE ROLE OF MEDIA IN POLITICAL ACTIVISM AND YOUTH EMPOWERMENT
Authors: Bansal Nishika ,   CMR University, Selvi S Pynthami , P Shreelakshmi ,   CMR University,   CMR University
Published: July 2024

The democratization of media in India has ushered in a dynamic era marked by both challenges and opportunities, particularly in the realms of political activism and youth empowerment. The primary aim of this article is to investigate the impact of media on political activism and the empowerment of youth within the Indian democratic context. It seeks to explore how various media platforms, including digital and social media, contribute to shaping political opinions and facilitating civic engagement among India’s younger population. This article delves into the multifaceted role of media in shaping India's democratic landscape, with a specific focus on its impact on political discourse, citizen engagement, and youth empowerment. Through a comprehensive review of existing literature and empirical evidence, the article explores the challenges posed by the spread of misinformation, regulatory constraints, and digital inequalities, while also highlighting the opportunities presented by citizen journalism initiatives, alternative media outlets, and social media platforms. By equipping citizens, especially the youth, with critical media literacy skills and promoting digital citizenship, India can navigate the complexities of media democratization to foster a more inclusive, participatory, and resilient democracy. Through this analysis, the article contributes to a deeper understanding of the intricate interplay between media, politics, and youth empowerment in the context of India's evolving democratic landscape. The future of Indian democracy will significantly depend on how well the nation manages to harness the potential of media platforms to foster informed political participation while mitigating the risks associated with digital media proliferation. As this article illustrates, nurturing a resilient and inclusive democratic process is contingent upon empowering the youth with the tools to critically engage with media and actively participate in the democratic governance of their country.
THE IMAGE OF A POSITIVE HERO IN THE UKRAINIAN MAGICAL TALE
Authors: Кyrychenko Vita ,   Pavlo Tychyna Uman State Pedagogical University, Denisyuk Oksana , Osipenko Natalia , Yovenko Larysa ,   Pavlo Tychyna Uman State Pedagogical University,   Pavlo Tychyna Uman State Pedagogical University,   Pavlo Tychyna Uman State Pedagogical University
Published: July 2024

The article examines the features of the image of a positive hero of a magical fairy tale, its content, context, and educational potential. The purpose of this article is to study of the characteristic features of the image of the positive hero of the Ukrainian fairy tale and the identification of his educational potential. The study of the image of the positive hero in Ukrainian magical fairy tales employs a multidisciplinary approach, incorporating folklore studies, literary criticism, and cultural anthropology. This method allows for an in-depth examination of the narrative structures, thematic elements, and cultural significance of the tales. The primary sources for this study include a comprehensive collection of Ukrainian magical tales, scholarly articles, and historical texts that provide insights into the evolution of these stories and their roles within Ukrainian culture. The types of heroes of magical tales are highlighted, their national and universal virtues are analyzed. Mythologemes and archaisms of the fairy tale "Kotygoroshko" were studied. It was concluded that the images of positive heroes of fairy tales in their own actions, activities, exploits, communication with other characters appear as integral human characters, exponents of the best virtues of the Ukrainian people. Heroes are consistent in their actions, value honor, justice, loyalty to family, people, and Motherland above all else. They wage an implacable struggle against evil in all its forms and always win. These are strong, courageous, honest, reliable knights, devoted to the end of the fight for the truth.
IMPACTO DA SÍNDROME DOS OVÁRIOS POLICÍSTICOS NA SAÚDE METABÓLICA: UMA REVISÃO ABRANGENTE
Authors: Mardini Lanzarini Giovanna , Naves Parreira Lívia , Silva Bertulucci Angotti Fernanda , Curado de Oliveira Maria Eduarda , Rodrigues Lara Gabrielly , Rodrigues Lara Winicius , Da Silva Geovana Mikaela da Silva , Corado Mendonça Matheus Henrique , Moura Gomes Guilherme Sabino , Keyd dos Santos Kallinne Keyd dos Santos
Published: July 2024

A Síndrome dos Ovários Policísticos (SOP) é uma endocrinopatia comum que afeta de 6% a 15% das mulheres em idade reprodutiva, dependendo dos critérios diagnósticos utilizados, como os de Rotterdam. A SOP é caracterizada por hiperandrogenismo, disfunção ovulatória e/ou ovários policísticos, apresentando sintomas como irregularidades menstruais, hirsutismo, acne e alopecia, afetando a qualidade de vida das pacientes. Além das implicações reprodutivas, a SOP está associada a significativos riscos metabólicos e cardiovasculares, incluindo resistência à insulina, obesidade central, dislipidemia e hipertensão, aumentando os riscos de diabetes tipo 2 e doenças cardiovasculares. A relação entre a SOP e a saúde metabólica é complexa, envolvendo resistência à insulina, hiperinsulinemia compensatória, inflamação crônica e disfunção endotelial, o que enfatiza a necessidade de uma abordagem terapêutica multifacetada. Este estudo objetiva analisar e sintetizar a literatura existente sobre a relação entre a SOP e a saúde metabólica, destacando os impactos metabólicos, mecanismos fisiopatológicos e abordagens terapêuticas. Foi realizada uma revisão abrangente, selecionando artigos relevantes das bases de dados, focando em termos como "Síndrome dos Ovários Policísticos" e "saúde metabólica". A análise revelou temas como resistência à insulina, obesidade central, dislipidemia, e os impactos na saúde cardiovascular e reprodutiva a longo prazo. Os achados sublinham a importância de intervenções farmacológicas, como metformina e anticoncepcionais orais, e não farmacológicas, como mudanças na dieta e exercício físico, além de novas terapias emergentes. A compreensão dos mecanismos subjacentes e a aplicação de estratégias terapêuticas eficazes são cruciais para melhorar os resultados de saúde das mulheres com SOP.
ROLE OF PROBIOTICS IN DENTISTRY: A QUESTIONNAIRE BASED STUDY
Authors: Diya Bhatia  , Aman  , Sahil  , Shivam  , Dr. Shourya Tandon  , Dr. Rangoli Srivastava
Published: July 2024

Aim: To assess the awareness and knowledge of dental students and practitioners regarding the role of probiotics in dentistry.
Methods: Questionnaire was administered to the students of a SGT University, Gurgaon and general practitioners to assess their knowledge, attitude and practice about rational use of probiotics with respect to oral health. Data was analysed after entering in to a Microsoft excel sheet and by using descriptive statistics.
Results : The study found that practicing dentists had the highest knowledge of probiotics, followed by postgraduates and undergraduates. Enhancing education on probiotics is necessary to improve their integration into dental practice.
Conclusion: The study underscores the need for improved probiotic education across all levels of dental training to enhance clinical integration. By addressing knowledge gaps, dental professionals can better utilize probiotics to improve patient care. The survey indicates a broad acceptance and awareness of probiotics among dental professionals, with significant emphasis on their benefits for oral and overall health. Both male and female respondents show strong support for incorporating probiotics into oral care, highlighting the potential for greater educational outreach and product development to meet this interest.
KEYWORDS: Probiotics, Oral health, Knowledge Aptitude Practice, Questionnaire
Peculiarities of physical therapy of chronic obstructive pulmonary disease: practical experience
Authors: Zhamardiy Valeriy O. , Kletsenko Liudmyla V. , Vyshar Yevheniia V. , Harkusha Sergii V. , Donchenko Viktoriia , Hordiienko Oksana V. , Voronetskyi Vadym B.
Published: July 2024

Aim: The aim of the study is todetermine the feasibility of using a home pulmonary rehabilitation program and evaluate its impact on patients with COPD in the GOLD B group
Materials and Methods: The study was conducted on the basis of the «Healthy Movements» studio (Poltava). Patients were involved in the study after receiving secondary (specialized) medical care, the basis of which was physical therapy treatment and exercise therapy in accordance with the clinical protocol approved by the internal order of the health care institution. A total of 30 people (aged 59 to 68.4 years) with II degree chronic obstructive pulmonary disease (50 % ≤ FEV1 < 80 % of normal) in remission took part in the study. Research methods: pedagogical, medical and biological , methods of mathematical statistics.
Results: Each patient confirmed the achievement of the general goal, namely, increasing the number of therapeutic exercises from 3 to 5 times a week, improving the quality of life, more active participation in improving their health and awareness of the disease. The patients considered self-management training to be the most valuable
Conclusions: Pulmonary rehabilitation is indicated for all patients, regardless of the degree of the disease. The most ef f ective are 6-12 week programs that include breathing exercises, self-management training and training of the patient’s environment, strengthening exercises, psychological support, diet therapy
Comparative analysis of the inf l uence of the shapes and dimensions of dental arches on the morphotopogeometric characteristics of the facial area
Authors: Potapchuk Anatoliy , Almashi Vasyl , Horzov Arsenii , Kostenko Svitlana
Published: July 2024

Aim: The aim of the article is a comparative analysis of the main aspects of existing medical and diagnostic measures in patients with abnormal types of occlusal relationships and methods of mathematical and graphic reproduction of the shape of the dental arches, taking into account the individual characteristics of the maxillofacial area.
Materials and Methods: The search for relevant publications related to the objective topic was carried out through scientific databases: Scopus, PubMed, BVS and Scielo.
Conclusions: The analysis of regression models of the reproduction of individual characteristics of the dental arch of the jaws will avoid errors that occur when comparing the actual sizes with their statistical norm, which will allow to correctly determine the proportionality and ratio of dif f erent departments of the dental and jaw system, the necessary amount of orthodontic measures in the treatment of anomalies of the dental arches.
Assessment of socio-demographic characteristics and social status of patients with negative symptoms in schizophrenia at different stages of the disease
Authors: Kushnir Yurii A. , Kozhyna Hanna M. , Abdryakhimova Tsira B. , Panko Tamara V.
Published: July 2024

Aim: To determine the features of socio-demographic characteristics of patients with negative symptoms of schizophrenia.
Materials and Methods: 252 patients with negative symptoms of schizophrenia took part in the study: 83 patients with the first episode of schizophrenia, 88 patients with schizophrenia in a state of exacerbation, and 81 patients with schizophrenia in a state of remission. During the research, a comprehensive approach was used, which consisted in the use of clinical-psychopathological, clinical-anamnestic and statistical research methods.
Results: Socio-demographic characteristics of patients with negative symptoms in schizophrenia were established. Among patients with the first episode of schizophrenia, the majority were of 20-29 years old, mostly with secondary education, unmarried, with a mental labor, with low and average levels of a material well-being, poor and satisfactory living conditions. Among patients with negative symptoms of schizophrenia in an exacerbation state, the majority was of persons of 30-49 years old, with a special secondary education, mostly divorced, with a disability, with a low and extremely low level of material well-being, with poor and very poor living conditions prevailed. Among patients with negative symptoms of schizophrenia in a state of remission, there was a predominance of persons of 30-39 and 50-60 years old, with a special secondary education, divorced, mainly with a physical labor, with a low and average level of material well-being and poor living conditions.
Conclusions: The obtained data can be used to establish diagnostic criteria for patients with negative symptoms in schizophrenia, depending on the dynamics of the disease.
An early detector of anastomosis leakage following colorectal cancer surgery in intensive care
Authors: Mungan İbrahim , Bostancı Erdal Birol , Türksal Erbil , Tezcan Büşra , Turan Sema
Published: July 2024

Colorectal cancer, comprising 10% of global cancer cases, often leads to anastomosis leakage (AL), a significant post-operative complication. Previous research on AL has highlighted the inflammatory response as a common risk factor and a potential diagnostic tool. This study aimed to investigate the inflammatory markers linked to AL and their prospective use as predictors of AL. This retrospective study was conducted in the intensive care unit of a state hospital in Ankara, Turkey. AL was detected through computed tomography and clinical evaluation (e.g., peritonitis and clinical deterioration). Inflammatory markers, including C-reactive protein and neutrophil-to-lymphocyte ratio (NLR), were examined in this study. A total of 410 patients were included in this study, among whom AL was observed in 26 cases (6.3%). The pre-operative levels of inflammatory markers did not differ between AL-positive and AL-negative groups, whereas the post-operative levels significantly differed between the groups (P < 0.05), particularly regarding post-operative NLR levels (P < 0.001). The predictive power of the difference in NLR was more prominent than the other inflammatory markers. In addition, the area under the curve of the NLR difference was sufficient to effectively predict AL. As the manifestation of AL signs and symptoms often occur in the later stages of inflammation, the early detection of inflammatory marker changes could signal the pre-emptive development of AL and enhance its management. In summation, the findings of this study further established the clinical potential of inflammatory markers for the early detection of AL, albeit requiring validation and support from additional prospective studies.
Successful treatment of vaccine-induced thrombotic thrombocytopenia in a patient with contraindication to standard-of-care early anticoagulation: A case report
Authors: Bhargava Anika , Chan Abigail
Published: July 2024

Vaccine-induced thrombotic thrombocytopenia (VITT) is a rare yet fatal side effect associated with adenoviral vector vaccines for coronavirus disease of 2019. We report a case of VITT in a previously healthy 43-year-old woman occurring 10 days after receiving the Johnson and Johnson (Ad26.COV2.S) vaccine. She presented with right-sided weakness, aphasia, and left gaze deviation. Computed tomography angiography of the head and neck revealed complete occlusion of the left internal carotid artery, left anterior carotid artery, and left middle cerebral artery with hemorrhagic conversion and midline shift. Pertinent laboratory results revealed acute thrombocytopenia and an elevated d-dimer level. She tested positive for platelet factor 4 (PF-4) antibodies, and a Doppler ultrasound revealed a deep vein thrombosis of the right femoral and popliteal veins. With these findings and the timing of vaccine administration, she had met the full criteria for VITT. While the crucial immediate treatment of VITT is therapeutic anticoagulation, its application for this case was contraindicated due to evolving hemorrhage and the need for an urgent decompressive craniectomy. An inferior vena cava filter was inserted, and intravenous immunoglobulin was administered, resulting in a suboptimal rise in platelet counts. She was then successfully treated with the addition of high-dose steroids and rituximab, eventually displaying therapeutic anticoagulation more than 2 weeks after the diagnosis. Two years after this diagnosis, she had slowly recovered from VITT. Her PF-4 antibodies are negative, and she remains only on prophylactic anticoagulation. This case highlights the importance of early recognition of symptoms to establish the correct diagnosis and the complexities of acute treatment of VITT in patients with contraindications to early therapeutic anticoagulation.
Regulatory role of lncRNA MALAT1 and miR-150-3p interaction in breast cancer progression and therapeutic implications
Authors: Vignesh Krishnamoorthy , Thangamalar Pattusamy
Published: July 2024

Long non-coding RNAs (lncRNAs) play crucial roles in cancer progression and metastasis. However, the precise regulatory mechanisms of MALAT1, an lncRNA, in breast cancer remain elusive. Consequently, this study explored the specific role of MALAT1 as a tumor promoter in breast cancer. Initially, MALAT1-small interfering RNA (siRNA) transfection resulted in the inhibition of breast cancer cell migration, colony formation, and invasion. Real-time polymerase chain reaction analysis also revealed increased E-cadherin expression and decreased vimentin and vascular endothelial growth factor (VEGF) mRNA levels subsequent to the transfection. Bioinformatic analysis further uncovered a specific interaction between MALAT1 and miR-150-3p, indicating elevated MALAT1 expression in breast cancer with a negative correlation to miR-150-3p expression. Furthermore, the overexpression of MALAT1 markedly suppressed miR-150-3p expression, indicating a reciprocal inhibition between the two. Luciferase reporter assays confirmed the specific association between miR-150-3p and MALAT1 at the sequence level. Furthermore, transfection with miR-150-3p mimic inhibited breast cancer cell migration, colony formation, and invasion, along with increased E-cadherin expression and decreased Vimentin and VEGF mRNA levels. Conversely, miR-150-3p inhibitor transfection led to opposing effects, reducing E-cadherin expression, and elevating vimentin and VEGF mRNA levels, while also inhibiting migration, colony formation, and invasion. Functionally, MALAT1 siRNA restrained breast cancer cell proliferation and migration while enhancing cellular apoptosis on administration to breast cancer cells, primarily mediated through miR-150-3p. Our findings delineate MALAT1 as a tumor growth-promoting gene antagonized by miR-150-3p. Building on these insights, this study proposes a potential therapeutic avenue for breast cancer treatment.
Zur Diagnose der gegenwärtigen Situation der Fachdidaktiken in der Lehrerbildung
Authors: Wyss Heinz , Reusser Kurt
Published: July 2024

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Fortbildungskurse für Praktikumslehrerinnen: Eine Nahtstelle von Theorie und Praxis in der Lehrerinnenbildung
Authors: Anliker Hans
Published: July 2024

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Advances in polymer micro needle technology for transdermal medication administration
Authors: Balusupati Balaraju , Balusupati Tarun , Budagala Gayathri , Chandu Babu Rao
Published: July 2024

By placing a medication plan into healthy, unblemished skin, the Transdermal Drug Delivery System (TDDS) is a simple method of delivering medications topically. The drug enters through the cuticle and then passes through the epidermis and dermis without entering the drug, primarily concentrating in the dermal layer. The use of microneedles for transdermal medicine delivery is becoming more and more popular due to problems associated with oral medication delivery methods. The medication's digestive tract exposes it to corrosive and catalytic substances found in the stomach, which causes the compound to denaturate and results in low bioavailability. This review focuses solely on the accessible literature from the past ten years in order to assess the various fabrication techniques, provide an update on the progress made in the creation of polymeric MNs, discuss the difficulties encountered in the process, and assess the potential uses of polymeric MNs in the healthcare industry. Microneedles are regarded as sturdy.
Pedagogical Perspectives in the Filmography of Lucian Pintilie
Authors: Coman Elena
Published: July 2024

Model for an entire generation Lucian Pintilie, a creative genius, takes on the role of revealing the world as it is, with all its shadows and ambiguities, as depicted in his films through absurdity, grotesque or farcical elements. The artistic approach of director Lucian Pintilie becomes redemptory, aiming to foster responsibility and awaken a collective consciousness. Lucian Pintilie’s intellectual preoccupation provides solid study material for the creators of the New Wave in the Romanian cinema, both through his films and through the volume Bricabrac, which includes his directorial poetics.
Uses of Cinematography and Theatre in Developing History Competencies. Proposals for Supporting Film-Making as Mainstream Teaching Strategy of Human Sciences
Authors: Răducanu Cristian
Published: July 2024

History lessons, in particular, and human sciences, in general, tend to be more appealing to students when film analysis or filmmaking and role play are regularly integrated in the teaching process. In the wake of the recent pandemic, which imposed remote learning, multimodal teaching strategies have gathered momentum due to their potential of increasing student creativity and insight into the topics under research, and of developing the formative goals of education. Expanding history lesson competencies, values and skills into an interdisciplinary approach to the humanities field by incorporating methods from cinematography and theatre is been proven to stimulate the authenticity of education, thus teaching sustainable citizenship. The article presents two examples on the use of film analysis and dramatization of source information as part of history lessons, which were applied successfully in the case of high school students. By aiming to implement multimodal digital methods of teaching, learning, and assessment at a systemic level, the article demonstrates that experimenting with and using the language and tools of filmmaking and improvisational theatre and dramatization has helped increase student intrinsic motivation to explore their potential vocation, has decreased absenteeism, has raised achievement levels, and enhanced the students’ overall understanding of life and wellbeing.
Cruising Corpoliterate Art Mediation. Reflections on the Mediation Program of Adina Pintilie’s ”You are Another me. A Cathedral of the Body”
Authors: Neugebauer Daniel
Published: July 2024

The study1 contextualises Adina Pintilie ́s recent work within the framework of corpoliteracy. To accomplish this, I introduced the concept of corpoliteracy as proposed by Bonaventure Soh Bejeng Ndikung, followed by my own expansion of the term as it applies to educational practices in art institutions. Body-semiotics and body- epistemologies will serve as entry points into a corpoliterate analysis of Pintilie’s work. This is a partial analysis that focuses on the body as a site for learning and unlearning but cannot cover all aspects of the multi-year, multi-media research conducted by Pintilie and her team. First, I chose an educational perspective, informed by recent methodologies and practices of museum education and artistic research, which are founded on practices of inclusion. Nevertheless, this perspective intersects with political, aesthetic, social, and institutional factors. Therefore, this approach is effective in terms of describing an artwork that manifests in domains before or beyond language. Second, I explored institutions as “social power plants” in order to examine how Pintilie’s practice relates to theories of radical museology. By applying the lens of corpoliteracy to Pintilie’s work as well as to the mediation practices of its exhibitions, the artistic quality and societal potency of the work can be addressed. Simultaneously, her artistic vision contributes to the expansion of corpoliteracy as a theoretical framework by continually challenging the institutions the projects manifest in. In the final section, I reflected on the mediation programme for Pintilie’s work, “You are another me. A Cathedral of the Body”, which attempted to put the aforementioned theory into practice.
The Politics of Transgression in De Humani Corporis Fabrica
Authors: Mihalcea Andreea
Published: July 2024

The film De Humani Corporis Fabrica has repeatedly been dubbed in the English-speaking film criticism media as a “non-fiction shocker” (Chang, 2023), a sample of “tactile cinema” (Mullen, 2023) with “ample gore on display” (Mintzer, 2022). This paper, firstly, aims to contradict these claims, as the film’s goal is not to elicit an immersive representation of the human body but a reflection on how it is instead objectified, abstracted, and interpreted by means of deconstructing the medical gaze and via a complex interplay between the viewer’s quasi-identification and alienation. To this end, it closely analyses the patterns in the camerawork, the various degrees of remediation of the medical imagery, and the relationships between denotation and connotation, highlighting the prevalence of de-dramatization strategies, which run counter to societal taboos and conventional representations of the hospital in popular culture as a sensationalized site of emergencies. As such, we argue that De Humani Corporis Fabrica is an essay film that seeks neither to “shock” viewers nor to mount a narrow institutional critique of the French sanitary system. By delving into the film’s intricate biopolitics, we outline how the various levels of transgression, the emphasis on “malfunction,” and the pervasiveness of technology are framed as symptoms of broader tensions between paternalistic modes of interaction and patient-centred approaches within the Western sanitary system at large. Finally, by interpreting the ending as a counterpoint to the objectifying gaze that the film lures us into adopting throughout, we consequently stress the film’s defiant sense of “anarchy,” as it urges us to reclaim “our” bodies, be them individual or collective.
Impact of Sex, Posture, and Phase on Back and Lower Extremity Moments and Muscle Excitation during Lifting Task: A Cross-sectional Study
Authors: Torres Rhodora Therese G. , Rui-xue Yan  , Chang Yoon Baek  , Hyeong-Dong Kim
Published: July 2024

Purpose

To investigate and compare back and lower extremity joint moments and muscle excitation during stoop and squat postures by incorporating sex-based differences and analyzing lifting phases.

Methods

18 healthy adults (9 males and 9 females; age: 24.44 ± 4.96 years, body mass: 66.00 ± 12.10 kg, height: 170.11 ± 9.20 cm, lean body mass: 48.46 ± 7.66 kg) lifted an object 30% of their lean body mass using squat and stoop postures. Marker-based motion capture, force plate, and surface electromyography were synchronously used to acquire joint moments and muscle excitation. A 3-way mixed model analysis was performed to determine the effects of sex, posture, and phase on internal joint moments and muscle excitation of the lower back and extremities.

Results

Significant differences were observed in the interaction of lifting posture and phase on lower extremity moments and excitation of rectus femoris and medial gastrocnemius. Individual effects of posture were significant for peak internal joint moments of the lower extremities only. Anterior lower extremity muscles showed significantly increased excitation during squat, whereas medial gastrocnemius was higher in stoop. Joint moments and muscle excitations were all higher during the lifting than the bending phase. Sex differences were found only in the peak lumbosacral sagittal plane moment and rectus femoris muscle excitation.

Conclusions

The study identified significant variations in the joint moments and muscle excitation in lifting, influenced by sex, posture, and phase, highlighting its complex nature. Overall interactions were lacking, however individual effects were evident, necessitating larger future studies.
Impact of Lower Limb Movements on Iliac Vein Stenting in Iliac Vein Compression Syndrome Patients: Insights from Computational Modeling
Authors: Jian Lu  , ZhenMin Fan  , Xia Ye  , Xiaoyan Deng  , Hai Feng  , Mingyuan Liu
Published: July 2024

Purpose

Iliac vein stenting is the primary treatment for patients with iliac vein compression syndrome (IVCS). However, post-stent placement, patients often experience in-stent restenosis and thrombosis. Despite this, the role of lower limb movements in the functioning of stents and veins in IVCS patients remains unclear. This study aimed to address this knowledge gap by developing a computational model using medical imaging techniques to simulate IVCS after stent placement.

Methods

This research used a patient-specific model to analyze the effects of lower extremity exercises on hemodynamics post-stent placement. We conducted a comprehensive analysis to evaluate the impact of specific lower limb movements, including hip flexion, ankle movement, and pneumatic compression, on the hemodynamic characteristics within the treated vein. The analysis assessed parameters such as wall shear stress (WSS), oscillatory shear index (OSI), and residence time (RRT).

Results

The results demonstrated that. Bilateral and left hip flexion were associated with pronounced regions of low WSS and high OSI at the iliac-vena junction and the stent segment. Additionally, active ankle exercise (AAE) and intermittent pump compression (IPC) therapy were found to enhance the occurrence of low WSS regions along the venous wall, potentially reducing the risk of thrombosis post-stent placement.

Conclusions

The exploration of the impact of lower limb movements on hemodynamics provides valuable insights for mitigating adverse effects associated with lower limb movements post iliac-stenting. Bilateral and left hip flexions negatively impacted blood flow, increasing thrombosis risk. However, active ankle exercise and intermittent pump compression therapies effectively improve the patency.
Shear rate induced viscosity change of human blood samples and blood mimicking fluids
Authors: Szabó Eszter , Baka Ernő Z. , Tamás Kornél
Published: July 2024

Purpose

The aim of this study was to measure blood and blood mimicking fluids viscosity at different shear rates (on the interval of 0.1-5000 1/s and 0.1-10000 1/s) while taking into consideration the measuring device’s capability and blood’s characteristics. We also provided the measurement results of the most accurate measuring program.

Methods

We measured blood samples from five donors, and four different blood mimicking fluid compositions. The measurements were done on an Anton Paar Physica MCR301 rotational rheometer with two measuring programs varying in the shear rate intervals, the number of measuring points and the measuring point durations.

Results

The results confirmed the significant shear thinning and thixotropic effects of blood. Blood mimicking fluids also had these characteristics. The measured blood viscosity values are in agreement with those of the literature.

Conclusions

It can be concluded that the step test program was able to give more stable results as the measured torque was over the nominal limit of 0.05 μNm over 0.1 1/s and over the selected torque limit of 0.5 μNm over 31.6 1/s. Blood mimicking fluid measurement results were different from that of the literature due to different measuring conditions. The sample consisting of water, glycerol and starch mimicked well blood’s behaviour and viscosity values at 37 degrees Celsius.
Gobernar por proyectos: el otro modelo de gobernanza territorial en México
Authors: Ugalde Vicente
Published: July 2024

El Gobierno federal mexicano ha publicado durante la última década distintos instrumentos de planificación para promover el ordenamiento del territorio y desarrollo regional. Su elaboración, a cargo de varias instancias administrativas, revelaría una gestión fragmentada y desarticulada. Este artículo indaga si la Estrategia Nacional de Ordenamiento Territorial (ENOT) 2020-2040, instrumento vigente en esta materia, logra restituirle al Estado mexicano la rectoría en la gobernanza territorial. Luego de una revisión de las herramientas normativas que constan en el Diario Oficial de la Federación, los hallazgos sugieren que la ENOT privilegia una gobernanza basada en proyectos prioritarios. El Tren Maya, el Programa de Desarrollo para el Istmo de Tehuantepec y el Programa Zona Libre de las Fronteras Norte y Sur son indicios de que otro modelo de gobernanza territorial ha surgido en México.
Indicadores sociodemográficos de población migrante venezolana en Ecuador y elementos para una política pública, 2015-2022
Authors: Varela Enríquez Marcelo , Salazar Espinoza Gustavo Adrián
Published: July 2024

El acercamiento econométrico que propone este artículo a indicadores sociodemográficos del Instituto Nacional de Estadística y Censos, como nacimientos, defunciones y egresos hospitalarios de la población venezolana en Ecuador entre 2015 y 2022, muestra un impacto notable en el saldo migratorio de esta comunidad. El crecimiento sostenido de migrantes venezolanos en el país subraya la importancia de diseñar políticas públicas que atiendan la evidencia de los datos obtenidos y apliquen un enfoque en derechos humanos. El estudio muestra que una de las necesidades más urgentes de esta población es el acceso a la salud pública.
Describing the play of three-year-old children in the home context
Authors: Varttinen Petra , Pihlaja Päivi , Af Ursin Piia
Published: July 2024

This study examines play in the Finnish home context by specifically concentrating on the forms of play, quality factors of play and social nature of play. It is of particular interest to study play especially of three-year-olds, because the research on play for this group, in home environment is scarce especially in the Finnish context. This study is part of longitudinal, multidisciplinary study (STEPS) and is based on the responses from 921 families who answered the questionnaires both at the study recruitment point and at three years. The data were gathered during the years 2011–2013 for the first time ever from the Finnish home context and are a basis for research to be done later. There is a need for this kind of descriptive and identifying study to understand play in the home context. The results suggest that play, and especially playing outdoors, had a strong position in children’s lives. Some forms of play were clearly gender-based and some demographic factors had a connection to the social nature of play. In addition, the level of participation in early childhood education and care was associated with play. No earlier studies have been conducted on the associations between participating in ECE and an increase in the sociability of play in the home context. Participating in ECE expands children´s social network and promotes possibilities to form friendships. In public discourse, the need to increase children's participation in ECEC has been strongly emphasized. This research supports these views.
Children’s everyday lifeworlds out of school, in Hong Kong, Melbourne, and Singapore: Family, enrichment activities, and local communities
Authors: Yelland Nicola , Chan Anita Kit-Wa , Bartholomaeus Clare
Published: July 2024

Children’s everyday lives beyond school need to be considered holistically, in a way which moves beyond time use. In this article we draw on our adaptation of Sarah Pink’s (e.g. 2012) video re-enactment methodology for considering children’s out-of-school lifeworlds with Year 4 children (9 and 10 years old) in the global cities of Hong Kong, Melbourne, and Singapore. The data presented and discussed here was part of a larger Global Childhoods Project with children in the three global cities of Melbourne, Hong Kong, and Singapore. We use video re-enactment methodology to ‘think with’, to open up lines of inquiry and create conversations about children’s lives in and between the cities. Through these we consider the specifics of each city context, as well as socioeconomic and sociocultural contexts and factors that may impact differently on children’s everyday lifeworlds out-of-school within the same city. In order to focus the scope of the article, we consider family routines, enrichment activities and local communities, as aspects that we find useful to reflect on when exploring what children’s lives look like, in and across locations. We focus on these as we are interested in how they might add to the complexities of thinking about children in each location. We move between thinking about the re-enactments themselves and broader literature to explore children’s out-of-school lifeworlds in the three cities, painting a picture of children’s lives and considering the contexts which make particular activities and practices possible and desirable.
A systematic review on factors influencing the development of children’s creativity
Authors: Smare Zaina , Elfatihi Mohamed
Published: July 2024

No one can deny that creativity is essential for survival and a key skill for prosperity in the 21st century. In an era where the skill of creativity is the pathway to development, it is crucial that we nurture children's creativity to better prepare them for academic, professional, and personal success. Systematic reviews on factors that could support or impede children’s creativity is scarce. The present review was conducted to fill this gap. Major electronic databases were searched and studies meeting predetermined selection criteria were analyzed. The search yielded 55 studies published between 2010 to 2022 in English. We classified influencing factors into four types: individual, family, educational, and socio-cultural factors. We concluded by discussing recommendations for parents, educational stakeholders and researchers.
Meta-Analisis Pengembangan Media Pembelajaran Android Pada Materi Koloid
Authors: Putri Larasati Ayu Putri , Fatah Abdul Hadjranul , Asi Nopriawan Berkat
Published: July 2024

Meta-Analisis merupakan kegiatan mengidentifikasi, mengevaluasi, menginterpretasi penelitian relevan untuk mengkombinasikan hasil studi yang telah ada dan dilakukan secara sistematis. Penelitian ini bertujuan untuk menganalisis kecenderungan sentral, variasi dan kesalahan dalam penelitian. Pada penelitian ini menggunakan sebanyak empat skripsi yang berkaitan dengan pengembangan media pembelajaran android pada materi koloid. Penelitian ini menggunakan metode penelitian meta-analisis kuantitatif dimana langkah-langkah dalam penelitian sebagai berikut 1) Penelusuran sumber dan identifikasi dokumen skripsi, 2) Penilaian ahli media, ahli materi dan peserta didik dianalisis nilai N dan I, 3) Menghitung effect size dan standard error,4) Nilai effect size  dan standard error dibuat menjadi forest plot. Penelitian mendapatkan hasil 1) Pada studi pengembangan media pembelajaran android pada materi koloid nilai ahli media, ahli materi dan peserta didik memiliki tingkat persentase yang berbeda disebabkan karena perbedaan lokasi, subjek penelitian, media yang digunakan, 2) Penilaian ahli media dan materi yang paling cocok digunakan dalam pembelajaran koloid dalam basis android ditinjau dari effect size dan forest plot yaitu pada studi atau penelitian NA-22, 3) Pada penilaian ahli materi studi RS-19 merupakan penilaian yang paling cocok untuk mendapatkan respon peserta didik pada pengembangan media pembelajaran androi pada materi koloid.