bluuebunny/crossref_metadata_2025 huggingface dataset:
Cana-de-Açúcar e Café na Região Extremo Sul da Bahia, Brasil: Uma Análise Espaço-Temporal e dos Fatores Socioeconômicos
Authors: Almeida Regiane Oliveira , Cruz Thyane Viana , Crepaldi Maria Otávia , Silva Leonardo Thompson , Sousa Ana Cristina , Cerqueira Everton Mateus Santos , Sena Anderson
Published: March 2023

A Região Extremo Sul da Bahia (RESB) possui aptidão agrícola para diversas culturas e já foi sujeita à expansão da cana-de-açúcar e do café. Assim, esse trabalho analisa a dinâmica espacial e temporal das monoculturas da cana-de-açúcar e do café na RESB e sua relação com índices socioeconômicos. A metodologia consiste em coleta e análise dos dados junto ao Instituto Brasileiro de Geografia e Estatística (IBGE), que é o principal provedor de informações geográficas e estatísticas do Brasil, a Companhia Nacional de Abastecimento (CONAB), que é responsável por fornecer informações técnicas para apoiar a tomada de decisão sobre a elaboração de políticas voltadas para a agricultura, e a Plataforma Atlas Brasil. Foram coletados dados sobre a área plantada e a quantidade produzida de cana-de-açúcar e de café na região entre os anos 1988 e 2019. Para compreender a relação entre a expansão e os fatores socioeconômicos, foram levantados dados referentes ao Produto Interno Bruto (PIB) e Índice de Desenvolvimento Humano Municipal (IDHM). Este trabalho identificou os principais municípios produtores de cana-de-açúcar (Caravelas, Mucuri, Medeiros Neto, Nova Viçosa, Lajedão, Ibirapuã e Santa Cruz Cabrália) e de café (Prado, Itamaraju, Porto Seguro, Eunápolis, Teixeira de Freitas e Itabela), e a expansão desses cultivos apresenta importância econômica para a região, porém apresenta pouca contribuição para a melhoria dos diversos fatores que compõem o IDHM dos municípios. Esse estudo concluiu que a expansão desses cultivos alterou a matriz agrícola da região devido a sua especialização na produção desses cultivos em detrimento de outros como o cacau, por exemplo.
Solos de ambientes lacustres do Pantanal Sul-Mato-Grossense
Authors: Nascimento Diogo Costa , Corrêa Guilherme Resende , Gradella Frederico Santos , Campos Prímula Viana , Koch Viviane Arantes , Vasconcelos Bruno Nery Fernandes
Published: March 2023

O Pantanal compreende um conjunto de paisagens heterogêneas e biodiversas de estimado valor ambiental, econômico e social. O estudo dos solos é efetivo para estratificar e compreender o funcionamento desses ambientes. Objetivou-se caracterizar e comparar solos de paisagens lacustres do Pantanal Sul-Mato-Grossense: baías (lagos de água doce), salinas (lagos alcalinos) e suas respectivas cordilheiras (cordões arenosos originalmente com vegetação florestal). Para tanto, realizou-se trabalho de campo com amostragens, em triplicata, de camadas superficiais do solo em 12 áreas representativas da baixa e alta Nhecolândia; procedeu-se determinações analíticas de 26 atributos do solo, totalizando 936 variáveis resposta e; análises estatísticas foram realizadas visando a síntese dos dados e apresentação dos resultados. Em ambas as paisagens predomina a fração areia fina na granulometria do solo. A classe textural dos solos variou de muito arenosa, arenosa média e média arenosa para as baías; muito arenosa para as cordilheiras, com Dp relacionada a presença do quartzo; e muito arenosa, arenosa média, média argilosa e argilosa para as salinas. Com relação aos atributos químicos e matéria orgânica, as baías se destacam pela maior acidez potencial (H+Al), teores de MO ligeiramente elevados e disponibilidade de íons metálicos, sobretudo Fe; nas cordilheiras, maiores médias de P-rem são mais evidentes; já os solos de salinas se relacionam a valores de pH mais alcalinos, elevada saturação por bases e altos índices de saturação por Sódio (ISNa). Paisagens de salinas apresentaram a maior variabilidade de dados e possuem atributos do solo que remetem a ação de diferentes processos ambientais.
Perceived Patient Safety Culture among Healthcare Providers in Southern Jordanian Hospitals during COVID-19 Pandemic
Authors:   Jordan University of Science and Technology, Alamsidin Asma , Alyahya Mohammad , Suliman Mohammad , Al-Sheyab Nihaya , ALBashtawy Mohammed
Published: March 2023

Background: The first step towards creating safe circumstances for patient care is to conduct thorough and ongoing assessments of the safety culture in the healthcare sector. Purpose: The purpose of this study was to assess healthcare professionals’ perceived culture of patient safety during the 2019 corona virus disease (COVID-19) outbreak in southern Jordanian hospitals. Methods: A descriptive, cross-sectional research of healthcare professionals (physicians, nurses and their administrators) was carried out. An Arabic translation of the Hospital Survey of Patient Safety Culture (HSPSC) questionnaire was used to collect information from 531 healthcare providers between July and November 2021 in four hospitals in Southern Jordan. Results: Nurses perceived ‘staffing’ as the highest dimension of the twelve dimensions of safety culture. However, they perceived ‘reporting patient safety events’ as the lowest dimension. The results show that healthcare providers perceived the twelve dimensions of patient safety culture as weakness areas that need improvement. The number of patient safety events reported by respondents in public hospitals was significantly (p<0.05) higher than the number of those reported by respondents in private ones (2.4±0.71 vs. 2.8±0.98, respectively). Conclusions: Hospitals in southern Jordan need to improve their patient safety culture procedures as well as patient safety aspects, such as personnel, handoffs and reporting-related components. Implications for Nursing: Hospital policies need to be adopted in a way that enhances a blame-free culture and an organized safety education program for all healthcare providers, especially new staff. Healthcare providers should be motivated to work as a team through a more reasonable allocation of authority and commission of work. Keywords: Patient safety, Safety culture, Southern Jordan, COVID-19 pandemic
Effect of Visiting Restrictions in the NICU during the Pandemic: A Literature Review
Authors:   Liberty University, Joseph Rachel A.
Published: March 2023

Background: Parents of infants in the neonatal intensive care unit (NICU) experienced a tremendous amount of stress with the changing policies which added to the trauma of having an infant in the NICU. While family-centered and developmental care are the norms in the NICU, the ‘visiting’ policy that involved complete lockdown, one parent at a time, restrictions on partners and extended families including grandparents, no kangaroo care, no breastfeeding, … etc. affected women emotionally, impacting breast milk production, breastfeeding and increased incidence of postpartum depression. Purpose: The purpose of this literature review is to explore the consequences of visiting restrictions in NICUs during the pandemic. Methods: Search terms, such as NICU, neonatal intensive care unit, parents, COVID-19 and visit, were used to search databases, such as CINAHL, PubMed and EBSCOhost, to identify peer-reviewed publications in English. The publications were after March 2020 by nature of the topic. Results: Visiting restrictions have a ripple effect on the infant and the family, where breastfeeding, milk production and parental mental health were affected. The changing policies have affected nurses too. Conclusion: Families are affected by the rapidly changing visiting policies during the COVID-19 pandemic. This has a ripple effect on mental health, bonding, breast milk production and family dynamics. Implications for Nursing: Babies born during these challenging times must be followed-up for their developmental milestones and social and educational achievement. Keywords: Neonatal intensive care unit: NICU, Parents, Visit, Pandemic, COVID-19.
An Evaluation of a 1/18o Resolution Regional Ocean Circulation Model of CROCO in the Southern Sunda Shelf
Authors: Apriansyah Apriansyah , Atmadipoera Agus S. , Jaya Indra , Nugroho Dwiyoga , Akhir Mohd. Fadzil
Published: March 2023

The Coastal and Regional Ocean Community Model (CROCO) was applied to simulate the three dimensional ocean circulation on the southern Sunda Shelf with a horizontal resolution of 1/18o and 40 vertical layers. This configuration is called as CROCO18-SSS. The initial and open boundary conditions were derived from a global reanalysis product at a resolution of 1/12o from the Copernicus Marine Environment Monitoring Service (CMEMS). The regional model was driven by atmospheric, tides, and river discharges data from a wide variety of datasets, each with a different resolution. To test the model performance and capabilities of the CROCO18-SSS model outputs including sea level anomaly, current velocity, temperature, salinity, and volume transport, we have compared in the simulation results with other reanalysis product and satellite-derived datasets. The CROCO18-SSS model outputs reproduced the regional ocean circulation well from observations and reanalysis products. For example, the reversal of the monsoonal current in the southern sunda shelf, as well as strong persistent southward Makassar throughflow and their interaction in the southern Makassar Strait, can be seen clearly. The vertical structure of the zonal current component was comparable to that of the reanalysis product reference. The seasonal shift in temperature and salinity, with the water becoming colder and saltier during the northwest monsoon and warmer and fresher during the southeast monsoon, was also accurately reproduced by the  CROCO18-SSS model.  Additionally, the mean volume transport calculated by the CROCO18-SSS model for the Makassar and Karimata Straits was comparable to that reported in previous studies.
Artificial Propagation of Pomadasys hasta (Bloch, 1790): A Key to Reach Sustainable Aquaculture
Authors: Ahmmed Shawon , Washim Mizanur Rahman , Rubel AKM Shafiqul Alam , Mondal Debashis Kumar , Sakib Md. Hashmi , Mahmud Yahia , Islam Md. Latiful
Published: March 2023

Reproduction of Pomadasys hasta was studied in captivity to establish an induced breeding protocol and larvae rearing tactics. Three distinct hormones viz., human chorionic gonadotropin (HCG), luteinizing hormone-releasing hormone analogues (LHRHa) and salmon gonadotropin hormone-releasing hormone (S-GnRHa) were injected to matured brooders in treatment 1 (T1), treatment 2 (T2) and treatment 3 (T3) but only 0.9% NaCl used in T4 as a control. In each treatment, three experimental trails, E1 (♀40:♂20 µg.kg-1), E2 (♀50:♂25 µg.kg-1) and E3 (♀60:♂30 µg.kg-1) were conducted along with three replications of each trail in order to optimize the hormone dose for the target species. The obtained results have aroused much attention as this is the first breakthrough on induced breeding of a grunter in the Indian subcontinent. Variation in fertilization rate, latency period, egg output and hatching rate in response to different treatments and trails were revealed here. Spawning was occurred between 33-48 h of injection in all the experiments at 17-25°C water temperature. Above all, the highest fertilization (95.45±2.34) and hatching (75.45±4.07) rates were observed in E2 of T2. After 22-26 h of fertilization, the larvae emerged from the egg membrane and the newly hatched larvae were 1.6-1.8 mm in length. Turning larvae into juveniles was noticed by 40–45 days post-hatch (dph) with scales on the entire body surface. The total length was recorded as 43.5±2.1 mm and average body weight as 0.7±0.2 g at 95 dph. This investigation unlocked a track for producing seed of P. hasta in a commercial hatchery for a sustainable aquaculture without hampering their wild stock.
Sexual Maturity and Macronutrient Contents in Diopatra sp. (Onuphidae, Polychaeta) Maintained at Different Salinity Levels
Authors: Wibowo Eko Setio , Pitriani Mellya Rizki , Rachmawati Farida Nur , Susilo Untung , Setiyono Eko , Atang Atang , Sucharitakul Phuping , Pamungkas Joko
Published: March 2023

Diopatra sp. (Onuphidae, Polychaeta) is an economically important polychaete species commonly used as a fishing bait by local anglers in Cilacap, Central Java Province. Some biological aspects of this local species, however, have not been studied yet. The aim of this research was to see the effect of salinity levels on the sexual maturity and the macronutrient contents of the animals. Diopatra specimens in the present study were collected from the intertidal mangrove habitats of Jeruklegi Village, Cilacap, in sexually immature condition. The worms were then transported to the laboratory and were maintained in containers with four different salinity levels, i.e. 10, 15, 20 and 25 ppt over the next two months. The sexual maturity of the animals were observed based on the presence or absence of coelomic gametes. Proximate analysis was performed to determine macronutrient contents of the animals. The effect of salinity levels on the animals' sexual maturity and macronutrient contents was analyzed using one-way ANOVA. The results showed that salinity levels did not significantly affect the sexual maturity level of Diopatra worms (p > 0.05). Similarly, they did not affect the protein and fat contents, but impacted the carbohydrate content of the animals (p < 0.05). The protein and the fat contents in Diopatra sp., i.e. 41–43% and 6–9%, respectively, met the amount required to be used as shrimp broodstock and fish feeds. While the species has the potential for use in local aquaculture, the annual reproductive cycle as well as the identity of the species, however, require further research.
A strophe, a chorus, and a bridge walk into a bar…
Authors: Martinelli Dario
Published: March 2023

Building up on Paul Cobley’s work on narrativity in film and literature, the present article aims at exploring how pop songs convey narrative elements via their own structure (or “format,” as it shall be called here), and their single components (intro, outro, bridge, refrain, etc.). Some of the most recurrent formats (particularly Strophe–Refrain and Chorus–Bridge) as well as some of the most unusual ones (e.g. the suite) are discussed within the framework of the three main narrative movements analyzed by Cobley (realism, modernism, and postmodernism), and additional parallels with literature and cinema will be proposed in the area of what here will be called “conceptual space” (diegesis, non-diegesis, fourth wall, etc.).
Transcending the mid-most target: Paul Cobley and the cultural implications of biosemiotics
Authors: Favareau Donald
Published: March 2023

Having been intimately aligned with the research agenda of biosemiotics since his colleague Thomas Sebeok first started using the term in 1992, Paul Cobley has consistently argued against the idea that the primary aim of biosemiotics is to make an intervention in the discourse and epistemology of the life sciences. Instead, he argues for the potential of a biosemiotically informed humanities for refashioning the ways in which we humans come to understand our situation within a world of signs and other organisms – as well as our existential duty of care for preserving the diversity and flourishing of both through the development of an anti-volunteerist ethics. Paul Cobley’s 2016 Cultural implications of biosemiotics fills a much-needed lacuna in the literature of biosemiotics in focusing with laser-like precision on those aspects of our human being – politics and aesthetics, education and ideology – that, Cobley rightly claims, have gone disproportionately under-analyzed and even under-appreciated in biosemiotics, due to its competing emphasis on reformulating biology. As one of the justly accused, I would like to take the occasion of this Festschrift to show the extent to which I now believe that Paul’s more expansive understanding of the purview of biosemiotics is, indeed, the proper one.
Living the duty of care: languaging in semiotic fields
Authors: Cowley Stephen J.
Published: March 2023

New hope can draw on anti-humanist duty of care. Turning from debate about how oneoughtto act in discursively produced “realities,” Paul Cobley advocates a bioethics of living in semiotic fields. Thanks to observership, humans can make good use of both the known and howthings appear as signs. For Cobley, the latter are “mind independent.” Once deemedreal, semiosis can unite the lawful, the perceivable and, at least, some of the unknown. However, skeptical as I am about metaphysics and mind, I shift the focus to languaging in semiotic fields: human perceiving, doing, and saying entangle languaging with nature’s simplex tricks (Berthoz, Alain. 2012.Simplexity: Simplifying principles for a complex world. New Haven, CT: Yale University Press). An ethical dimension runs through how we feel, speak and, thus, actualize practices. The duty of care, the known, the knowable, and the unknowable unite inthingishness. What appear to us as signs ensure that perceiving-acting can draw, at times, on fictions and, at others, precision tools. Humans tether sense to wordings as, without end, we actualize practices. Stories bring ethical awareness to attitudes, action, and the due care that shapes understanding and response to institutions. In offering a distributed perspective on language, one makes possible an ecolinguistics that works for life-sustaining relations between humans, nonhumans and what we call “things.”
Hyers-Ulam stability of isometries on bounded domains-II
Authors: Choi Ginkyu , Jung Soon-Mo
Published: March 2023

The question of whether there is a true isometry approximating the

ε

\varepsilon

-isometry defined in the bounded subset of the

n

n

-dimensional Euclidean space has long been considered an interesting question. In 1982, Fickett published the first article on this topic, and in early 2000, Alestalo et al. and Väisälä improved Fickett’s result significantly. Recently, the second author of this article published a paper improving the previous results. The main purpose of this article is to significantly improve all of the aforementioned results by applying a basic and intuitive method.
Asymptotic study of Leray solution of 3D-Navier-Stokes equations with exponential damping
Authors: Blel Mongi , Benameur Jamel
Published: March 2023

We study the uniqueness, the continuity in

L

2

{L}^{2}

, and the large time decay for the Leray solutions of the 3D incompressible Navier-Stokes equations with the nonlinear exponential damping term

a

(

e

b
∣
u

∣

2

−
1

)

u

a\left({e}^{b| u{| }^{{\bf{2}}}}-1)u

, (

a
,
b
>
0

a,b\gt 0

).
Lack of exposure to pharmacogenomics education among the health care providing students in the West Bank of Palestine
Authors: Jarrar Yazun , Musleh Rami , Hamdan Anas , Ghanim Mustafa , Alqub Malik , Abudahab Sara
Published: March 2023

Objectives

Evaluating the knowledge in pharmacogenomics (PGx) is the first step toward the implementation of PGx testing in clinical practice. This survey aimed to evaluate the knowledge of PGx testing among healthcare providing students at the top-ranked university in the West Bank of Palestine.

Methods

First an online questionnaire consisting of 30 questions regarding the demographic, knowledge, and attitude toward pharmacogenomics testing was structured and validated. Then the questionnaire was distributed to 1,000 current students from different fields.

Results

696 responses was received. The results showed that almost half of the participants (n=355, 51.1%) have never took any courses about PGx during their university training. Only 81 (11.7%) of the students who took the PGx course stated that it helped them understanding how genetic variations affect drug response. The majority of the students were uncertain (n=352, 50.6%) or disagreed (n=143, 20.6%) that the lectures during university education described the effects of genetic variants on drug response. Although most of the students (70–80%) answered that genetic variants can indeed affect the drug’s response, only 162 students (23.3%) responded that VKORC1 and CYP2C9 genotypes influence the response to warfarin. In addition, only 94 (13.5%) students were aware that many medicine labels include clinical information about PGx testing provided by the FDA.

Conclusions

It is concluded from the results of this survey that there is a lack of exposure to PGx education associated with poor knowledge of PGx testing among the healthcare providing students in the West Bank of Palestine. It is recommended to include and improve the lectures and courses regarding PGx as this will have a major impact on precision medicine.
Isolation and purification of high-molecular weight hemicelluloses from radiata pine wood chips prior to thermo-mechanical pulp (TMP) production
Authors: Widsten Petri , Murton Karl , Thumm Armin , Bridson James H.
Published: March 2023

A novel thermo-mechanical pulping (TMP) process has been developed to produce a by-product rich in high-molecular weight (MW) hemicelluloses, a potential raw material for barrier coatings and films. This process uses prehydrolysis to solubilise the hemicelluloses followed by chip compression to separate the soluble material from the wood matrix. The pressate from the chip compression stage was dark-coloured and had a high content of high-MW hemicelluloses and lignin. However, isolating the high-MW material from the pressate directly by ultrafiltration was not feasible because of membrane fouling by dissolved lignin and wood extractives, while coloured impurities are undesirable for many potential applications. To solve these problems the pressate was purified using XAD adsorbent resin to remove low-MW lignin, extractives and colour. Ultrafiltration of the purified pressate yielded lightly coloured high-MW hemicellulose with a low content of lignin and well suited for barrier films and coatings.
Synthetic biology open language (SBOL) version 3.1.0
Authors: Buecherl Lukas , Mitchell Thomas , Scott-Brown James , Vaidyanathan Prashant , Vidal Gonzalo , Baig Hasan , Bartley Bryan , Beal Jacob , Crowther Matthew , Fontanarrosa Pedro , Gorochowski Thomas , Grünberg Raik , Kulkarni Vishwesh , McLaughlin James , Mısırlı Göksel , Oberortner Ernst , Wipat Anil , Myers Chris
Published: March 2023

Synthetic biology builds upon genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. When designing a synthetic system, synthetic biologists need to exchange information about multiple types of molecules, the intended behavior of the system, and actual experimental measurements. The Synthetic Biology Open Language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, following an open community process involving both bench scientists and scientific modelers and software developers, across academia, industry, and other institutions. This document describes SBOL 3.1.0, which improves on version 3.0.0 by including a number of corrections and clarifications as well as several other updates and enhancements. First, this version includes a complete set of validation rules for checking whether documents are valid SBOL 3. Second, the best practices section has been moved to an online repository that allows for more rapid and interactive of sharing these conventions. Third, it includes updates based upon six community approved enhancement proposals. Two enhancement proposals are related to the representation of an object’s namespace. In particular, the Namespace class has been removed and replaced with a namespace property on each class. Another enhancement is the generalization of the CombinatorialDeriviation class to allow direct use of Features and Measures. Next, the Participation class now allow Interactions to be participants to describe higher-order interactions. Another change is the use of Sequence Ontology terms for Feature orientation. Finally, this version of SBOL has generalized from using Unique Reference Identifiers (URIs) to Internationalized Resource Identifiers (IRIs) to support international character sets.
Comparison of regular with NPH insulin vs. premix insulin in children and adolescents with type 1 diabetes in a resources-limited setting: a retrospective data analysis
Authors: Sagna Yempabou , Bagbila Wend Pagnangde Abraham Hermann , Bognounou René , Ilboudo Alassane , Sawadogo Nongoba , Kyelem Carole G. , Guira Oumar , Ouedraogo Macaire S. , Drabo Joseph Y.
Published: March 2023

Objectives

Few studies addressed the efficacy of human insulin regimens (mostly premix insulin) used in many low-and-middle income countries on glycemic control of children and adolescents with diabetes. The aim of this study was to assess the efficacy of the premix insulin on the glycated hemoglobin (HbA1c) in comparison to the regular with NPH insulin scheme.

Methods

A retrospective study was carried out from January 2020 to September 2022 on patients with type 1 diabetes aged below 18 years followed in Burkina Life For A Child program. They were categorized into three groups, on regular with NPH insulin (Group A), on premix insulin (Group B) and on regular with premix insulin (Group C). Outcome was analyzed based on HbA1c level.

Results

Sixty-eight patients with a mean age of 15.38 ± 2.26 years and the sex ratio (M/W) 0.94 were studied. There were 14 in Group A, 20 in Group B, and 34 patients in Group C. The mean HbA1c value in the corresponding insulin regimen was 12.8 ± 1.39%, 9.87 ± 2.18%, and 10.66 ± 2.1%, respectively. Glycemic control was better in Groups B and C than Group A (p<0.05) but there was no difference between groups B and C.

Conclusions

Our results indicate that the use of premix insulin gives a better glycemic control than NPH insulin. However, further prospective study of these insulin regimens with a strengthening education strategy and glycemic control by continuous glucose monitoring and HbA1c is required to corroborate these preliminary findings.
On the persistence of SVO: the case of Modern Eastern Armenian
Authors: Samvelian Pollet , Faghiri Pegah , Khurshudyan Victoria
Published: March 2023

This study addresses the issue of unmarked word order in Modern Eastern Armenian (MEA), typologically considered a flexible (S)OV language due to its being strongly left-branching as well as the syntactic properties of its VP (focus, bare objects, low adverbs). However, Armenian grammars generally consider (S)VO to be the canonical order. We have conducted a corpus study and two sentence production experiments to tackle this controversy. These studies show that the placement of direct objects (DOs) is mainly triggered by definiteness. While definite DOs are overwhelmingly postverbal, indefinite DOs display a strong preference for preverbal placement. This implies a “typological discrepancy”: although MEA is a strongly left-branching language, the unmarked placement of definite DOs is postverbal. We account for this “discrepancy” based on areal, historical and cognitive factors. Contact with OV languages has resulted in a consistent shift from right to left-branching in Armenian, whereas word order at the clausal level has resisted the shift because MEA makes optimal use of each order in accordance with their cognitive advantages. The evolution of word order in MEA is an illustration of the universal crosslinguistic bias toward SVO.
Mechanical degradation of sugar palm crystalline nanocellulose reinforced thermoplastic sugar palm starch (TPS)/poly (lactic acid) (PLA) blend bionanocomposites in aqueous environments
Authors: Nazrin Asmawi , Sapuan Salit Mohd , Zuhri Mohamed Yusoff Mohd , Tawakkal Intan Syafinaz Mohamed Amin , Ilyas Rushdan Ahmad
Published: March 2023

The concerning issue regarding petrochemical plastic wastes had prompted scientists and researchers to develop biodegradable plastic in effort to tackle environmental pollution. Alternative bioresources such as poly (lactic acid), sugar palm starch and nanocellulose fibre were utilized in producing cheap, biodegradable and sustainable plastic with satisfactory mechanical properties for food packaging application. In this study, sugar palm crystalline nanocellulose (SPCNC) was priorly dispersed in thermoplastic sugar palm starch (TPS) before melt blended with poly (lactic acid) (PLA) and later compress moulded into a sheet form. Initial biodegradation test of PLA100 and all PLA/TPS blends bionanocomposite samples indicated that PLA60TPS40 has the least variation in weight loss due to the good miscibility between TPS and PLA promoting the reinforcement of SPCNC. Greater weight losses in seawater (17.54%), river water (18.97%) and sewer water (22.27%) result in greater mechanical degradation as observed at the reduction of tensile strength from 12.11 MPa to 2.72 MPa in seawater, 1.48 MPa in river water and 0.40 MPa in sewer water. Similarly, higher weight losses in seawater (22.16%), river water (21.6%) and sewer water (23.09%) correlated with the reduction of flexural strength from 18.37 MPa to 3.5 MPa in seawater, 3.83 MPa in river water and 3.6 MPa in sewer water. The scanning electron microscope (SEM) images of tensile fracture morphology demonstrated clear porous structure due to the removal of starch particles by microbial activity. The homogenous structure of PLA60TPS40 had a steady and consistent degradation, which wholly diminished the interfacial adhesion that led to mechanical properties losses. The mechanical strength reduction clarified that the biodegradation rate within the media used might be able to resolve the excessive non-biodegradable plastic waste in open waters.
A Halpern-type algorithm for a common solution of nonlinear problems in Banach spaces
Authors: Zegeye Habtu , Boikanyo Oganeditse A.
Published: March 2023

In this article, we propose a Halpern-type subgradient extragradient algorithm for solving a common element of the set of solutions of variational inequality problems for continuous monotone mappings and the set of f-fixed points of continuous f-pseudocontractive mappings in reflexive real Banach spaces. In addition, we prove a strong convergence theorem for the sequence generated by the algorithm. As a consequence, we obtain a scheme that converges strongly to a common f-fixed point of continuous f-pseudocontractive mappings and a scheme that converges strongly to a common zero of continuous monotone mappings in Banach spaces. Furthermore, we provide a numerical example to illustrate the implementability of our algorithm.
Association between Percentage of Neutrophils at Admission and in-Hospital Events in Patients ≥75 Years of Age with Acute Coronary Syndrome
Authors: Tian Cuihong , Zhu Zhaowei , Xie Hebin , Wei Cheng , Fang Zhenfei , Hu Xinqun , Zhou Shenghua
Published: March 2023

Objective: The study aimed to evaluate the role of the neutrophil percentage (N%) at admission in predicting in-hospital major adverse cardiovascular events (MACE) in patients ≥75 years of age with acute coronary syndrome (ACS).

Methods: A total of 1189 patients above 75 years of age with ACS hospitalized at the Second Xiangya Hospital between January 2013 and December 2017 were enrolled in this retrospective study. Receiver operator characteristic curve analysis was performed to calculate the optimal N% cut-off value for patient grouping. The in-hospital MACE consisted of acute left heart failure, stroke and any cause of death. Multivariable logistic analyses were used to assess the role of N% in predicting MACE in older patients with ACS.

Results: The patients were divided into a high N% group (N% ≥74.17%, n=396) and low N% group (N%<74.17%, n=793) according to the N% cut-off value (N%=74.17%). The rate of MACEs during hospitalization was considerably higher in the high N% group than the low N% group (27.5% vs. 9.6%, P<0.001). After adjustment for other factors, high N% remained an independent risk factor for in-hospital MACE in older patients with ACS (odds ratio 1.779, 95% confidence interval 1.091–2.901, P=0.021).

Conclusion: High N% at admission is an independent risk factor for in-hospital MACE in patients above 75 years of age with ACS.
PIF7‐mediated epigenetic reprogramming promotes the transcriptional response to shade in Arabidopsis
Authors: Yang Chuanwei , Zhu Tongdan , Zhou Nana , Huang Sha , Zeng Yue , Jiang Wen , Xie Yu , Shen Wen‐Hui , Li Lin
Published: March 2023

For shade‐intolerant plants, changes in light quality through competition from neighbors trigger shade avoidance syndrome (SAS): a series of morphological and physiological adaptations that are ultimately detrimental to plant health and crop yield. Phytochrome‐interacting factor 7 (PIF7) is a major transcriptional regulator of SAS in Arabidopsis; however, how it regulates gene expression is not fully understood. Here, we show that PIF7 directly interacts with the histone chaperone anti‐silencing factor 1 (ASF1). The ASF1‐deprived asf1ab mutant showed defective shade‐induced hypocotyl elongation. Histone regulator homolog A (HIRA), which mediates deposition of the H3.3 variant into chromatin, is also involved in SAS. RNA/ChIP‐sequencing analyses identified the role of ASF1 in the direct regulation of a subset of PIF7 target genes. Furthermore, shade‐elicited gene activation is accompanied by H3.3 enrichment, which is mediated by the PIF7‐ASF1‐HIRA regulatory module. Collectively, our data reveal that PIF7 recruits ASF1‐HIRA to increase H3.3 incorporation into chromatin to promote gene transcription, thus enabling plants to effectively respond to environmental shade.
Recycling of the actin monomer pool limits the lifetime of network turnover
Authors: Colin Alexandra , Kotila Tommi , Guérin Christophe , Orhant‐Prioux Magali , Vianay Benoit , Mogilner Alex , Lappalainen Pekka , Théry Manuel , Blanchoin Laurent
Published: March 2023

Intracellular organization is largely mediated by actin turnover. Cellular actin networks continuously assemble and disassemble, while maintaining their overall appearance. This behavior, called “dynamic steady state,” allows cells to sense and adapt to their environment. However, how structural stability can be maintained during the constant turnover of a limited actin monomer pool is poorly understood. To answer this question, we developed an experimental system where polystyrene beads are propelled by an actin comet in a microwell containing a limited amount of components. We used the speed and the size of the actin comet tails to evaluate the system's monomer consumption and its lifetime. We established the relative contribution of actin assembly, disassembly, and recycling for a bead movement over tens of hours. Recycling mediated by cyclase‐associated protein (CAP) is the key step in allowing the reuse of monomers for multiple assembly cycles. ATP supply and protein aging are also factors that limit the lifetime of actin turnover. This work reveals the balancing mechanism for long‐term network assembly with a limited amount of building blocks.
Effects of core layer fiber size and face-to-core layer ratio on the properties of three-layered fiberboard
Authors: Ayrilmis Nadir , Akbulut Turgay , Yurttaş Elif
Published: March 2023

The objective of this study was to transfer benefits of three-layered particleboards to medium density fiberboard (MDF) manufacture by using coarse fibers and, thus use less energy and lower-cost fibers as core layer material. In the first phase of this study, the effect of wood fiber size in the core layer on the properties of MDF was investigated. In the second phase, the effect of surface to core layer ratio (30/70, 40/60, 50/50, 60/40, and 70/30) on the properties of the MDF was investigated. The surface layers of the panels consisted of fine fibers. The wood fibers were produced using a thermo-mechanical refining process. The length and thickness of the fibers considerably increased with increasing defibrator discs distance. The 24-h TS values of the MDF specimens decreased from 36.8 to 34.2% as the fiber length in the core layer was increased from 4.3 to 11.5 mm. However, further increases in the fiber length increased TS values. Similarly, the bending strength, bending modulus, and internal bond strength increased with increasing fiber length (up to 11.5 mm) and thickness (up to 0.73 mm). The bending properties of the MDF specimens improved with increasing surface layer ratio, while the internal bond strength decreased.
Filler bondability factor as a tool for maximizing the potential of mineral additives in paper production
Authors: Song Shunxi , Wang Peiyao , Zhang Meiyun
Published: March 2023

Increasing filler content in paper while maintaining paper strength is a continuous need in the paper industry. The bonds between cellulosic fibers and fillers are essential to increase filler level in paper. Besides tensile strength, which traditionally has been used to investigate different fillers on fiber bonding, a new factor, i.e. a filler bondability factor, can be applied in evaluating the mitigation effect of filler addition on fiber bonding. This factor shows its effectiveness in optimizing the key parameters for filler modification and the choice of filler, and it helps to maximize the use of filler in the paper industry.
Revisitando proposições conceituais relacionadas a memoriais institucionais
Authors: Jorge Cristina de Oliveira , Duarte Glaucius Décio
Published: March 2023

As instituições públicas de ensino buscam incorporar tecnologias, acompanhando os avanços e as facilidades que as mesmas asseguram. No contexto da memória institucional não é diferente, as instituições procuram formas de salvaguardar sua história usando recursos de tecnologia para preservá-la às gerações futuras. Apresentamos, nesta construção, uma abordagem qualitativa de natureza aplicada, a partir da pesquisa exploratória, que aproxima nesse momento da pesquisa o investigador com seu objeto, amparado na averiguação bibliográfica. Nesse contexto, identificamos alguns conceitos que fazem parte da constituição de um Memorial Institucional, assim como a nomenclatura que se harmoniza com o tipo de documentos e suportes que fazem parte do referido Memorial. Dessa forma, intuímos neste trabalho entender esses conceitos e exemplificar a sua variedade, de maneira que venham a contribuir com rotinas metodológicas aplicadas na instituição que melhor segmentam seu acervo, visando o resgate e a constituição da identidade institucional.
A statistics-based review on island detection methods in microgrids: Overall investigation and state-of-the-art
Authors: Damanjani Amin , Hosseini Abardeh Mohamad , Azarfar Azita , Hojjat Mehrdad
Published: March 2023

In this paper, a comprehensive statistics-based review of islanding detection methods (IDMs) in microgrids (MGs) is presented. Islanding detection is the situation of isolating the MG from the main grid whether programmed as a result of load managing purposes or un-programmed due to the occurrence of faults. Islanding detection is a vital issue in MG's analyses due to the prevention of subsequent protection problems in the power system. In other words, when the MG's operation mode changes, the current passing through the protective devices changes subsequently and the protection system should be able to adapt the new settings to the protective devices. So, IDMs are vital for electrical engineers to overcome the abovementioned protection issue. This review paper surveys the existing literature in IDMs by concentration on total publications, type of publications (journal, conference paper, or book), five authors with the highest number of publications (including the affiliations), and five most published sources. Also, the five most cited publications and state-of-the-art IDMs are investigated in detail, utilizing some known and novel categorizations. This paper will be useful for the MG's researchers to know the most desirable IDMs, especially in recent years, and provides an insightful overview for future studies.
A motoros egységek aktivitásának változása a biceps brachii izomban különböző intenzitású izometriás terhelések hatására
Authors: Hegedüs Ádám , Kopper Bence Ádám
Published: March 2023

Bevezetés: Daganatos betegeknél az izomtömeg csökkenése számos
esetben és daganattípusnál megfigyelhető. Ennek hatására a beteg életminősége
drasztikusan romolhat, képtelenné válhat az önellátásra. Napjainkban a daganat
primer kezelése mellett előtérbe került a betegek fizikális edzése is, hogy
életminőségüket fenntarthassák. Ehhez egy kulcs lehet a hirtelen izomvesztést
megelőzni képes ellenállásos edzés, amelyet a primer kezelés mellett képes
végezni a beteg, s erre egy lehetőség lehet az izometriás edzés.
Célkitűzés: Célunk az volt, hogy mérjük a biceps brachii
izom aktivációs frekvenciájának karakterisztikáit alanyainkban egy fárasztási
protokoll során, miközben állandó kontrollált izometriás feszülést hozunk létre
az izomban. Módszer: Vizsgálatunkban 19 egészséges egyetemi
hallgató vett részt. A domináns oldal meghatározása után felmértük az alanyok
egyismétléses maximumát a GymAware RS eszközzel, majd ennek kiszámítottuk a
65%-át és a 85%-át. Elektródákat helyeztünk a biceps brachii izomra, és a
hallgatóknak teljes kifáradásig kellett tartaniuk 65%-on és 85%-on a súlyt.
Közvetlenül ezután izometriás maximális kontrakciót (Imax) hajtottak végre az
alanyok. A mért elektromiográfiás regisztrátumot 3 egyenlő részre osztottuk, s
az első, a középső és az utolsó 3 mp-et (W1, W2, W3) elemeztük.
Eredmények: Eredményeink azt mutatják, hogy a fáradással
összhangban mind 1RM 65%-os, mind 1RM 85%-os terhelésnél nő az alacsony
frekvenciájú motoros egységek aktivitása, míg a magas frekvenciájú motoros
egységek aktivációja csökken. Megbeszélés: A jelen kutatás
összhangban van korábbi vizsgálatunkkal. Következtetés:
Vizsgálati protokollunk nem alkalmas a magas frekvenciájú motoros egységek
hosszan tartó aktivációjára, mert az idő múlásával csökken a nagy motoros
egységek aktivitása. Orv Hetil. 2023; 164(10): 376–382.
Örökletes vesetumor-szindrómák.
Authors: Sánta Fanni , Semjén Dávid , Kuthi Levente
Published: March 2023

A vesedaganatok egy része örökletes tumorszindrómákhoz társultan alakul ki. Ezek
klinikai megjelenése változatos, és előfordulhat, hogy a vesedaganat a betegség
első manifesztációja, ezért fontos, hogy a patológusok tisztában legyenek
azokkal a makroszkópos jelekkel és szöveti elváltozásokkal, amelyek alapján a
tumorszindróma lehetősége felvethető. Ebben a közleményben összefoglaljuk és
szemléltetjük a kialakuló vesedaganatok jellemzőit, a genetikai hátteret és az
extrarenalis eltéréseket a következő kórképekben: Von Hippel–Lindau-szindróma,
örökletes papillaris vesesejtes carcinoma szindróma, örökletes leiomyomatosis és
vesesejtes carcinoma szindróma, Birt–Hogg–Dubé-szindróma, sclerosis tuberosa,
örökletes paraganglioma/phaeochromocytoma szindróma, illetve
BAP1-tumorszindróma. A dolgozat végén tárgyaljuk azokat a
tumorszindrómákat, amelyekben fokozott a Wilms-tumor kialakulásának kockázata.
Az ilyen betegek ellátása holisztikus szemléletet és multidiszciplináris
megközelítést igényel, ezért munkánk célja, hogy felhívjuk a vesetumorok
ellátásában részt vevő kollégák figyelmét ezekre a ritka, ugyanakkor élethosszig
tartó ellátást igénylő betegségekre. Orv Hetil. 2023; 164(10): 363–375.
Rosszindulatúan elfajult nyaki branchiogen cysta
Authors: Jakab-Péter Kinga , Háromi István , Kaszás Bálint , Oláh Zsanett , Szanyi István , Somogyvári Krisztina
Published: March 2023

A nyaki branchiogen cysta az egyik leggyakoribb nyaki fejlődési rendellenesség.
Ismert a malignus elfajulása, melynek diagnosztizálására, az ismeretlen
lokalizációjú primer laphámcarcinoma nyaki áttététől való elkülönítésére szigorú
kritériumrendszerek léteznek. Ugyanakkor a szakirodalomban a diagnózis
létjogosultsága a mai napig vita tárgyát képezi. Közleményünkben egy 69 éves
nőbeteg esetét ismertetjük, aki bal oldali, állkapocs alatti duzzanat miatt
jelentkezett Klinikánkon. Hosszas kivizsgálást követően felmerült ismeretlen
primer tumor nyaki áttétének gyanúja, mely miatt pánendoszkópiát és módosított
radikális nyaki dissectiót végeztünk. Végül a szövettani feldolgozást követően
lateralis nyaki cysta talaján kialakult laphámcarcinoma igazolódott. A műtétet
követően a beteg adjuváns kemoterápiában és sugárkezelésben részesült. Az eset
kapcsán ismertetjük a diagnózis felállításának nehézségeit,
differenciáldiagnosztikai problémáit és a kapcsolódó nemzetközi irodalmat. Orv
Hetil. 2023; 164(10): 388–392.
Dongasejtes angioma
Authors: Tolvaj Balázs , Hevér Tímea , Kálmán Bernadette , Vadvári Árpád
Published: March 2023

A traumás lépruptura gyakori sérülés. A nem traumás, más néven spontán vagy
patológiás lépruptura viszont ritka, de potenciálisan életveszélyes állapotot
okozó betegség. A spontán lépruptura primer lépdaganat miatt történő kialakulása
ritkaság. Tanulmányunk egy léprepedést okozó, különleges, jóindulatú daganat
esetét mutatja be. 78 éves nőbetegünk bal vállfájdalom és mellkasi diszkomfort
miatt került kórházba. Vérnyomása alacsony volt; a laborvizsgálatok anaemiát
mutattak ki, a felhasi területet is leképező mellkas-CT lépruptura gyanúját
vetette fel. A sürgősséggel elvégzett splenectomia során a hasüregben nagy
mennyiségű vér volt. Az eltávolított lép patológiai vizsgálata makroszkóposan
multifokális cysticus elváltozást talált, mely a léprepedéshez vezetett.
Mikroszkóposan az immunhisztokémiai vizsgálatok dongasejtes angiomát igazoltak.
A dongasejtes angioma egy lépben keletkező ritka, jóindulatú érdaganat, amelyről
úgy gondolják, hogy a dongasejtekkel bélelt vörös pulpasinusokból származik.
Közleményünk célja, hogy ismertesse a traumás előzmény nélkül, hirtelen
bekövetkezett léprepedés egy szokatlan okát, a Magyarországon még nem publikált
jóindulatú lépmegbetegedést, a dongasejtes angiomát. Orv Hetil. 2023; 164(10):
393–397.
QUALITY PRACTICES EVALUATION IN THE PRE-ANALYTICAL PHASE OF DIFFERENT CLINICAL LABORATORIES OF THE VALLE DE ABURRÁ.
Authors: Gallego Lina Maria Ospina , Lopera Natalia Gallego , Martínez Juan Felipe Zapata , Araque Claudia Maria Cuervo
Published: March 2023

The pre-analytic phase covers in chronological order; From the physician's request, indication, patient preparation, obtaining the primary sample, transportation to and within the laboratory, and ending when the analytical procedure begins. The objective of this study was to evaluate quality practices in the pre-analytical phase of different clinical laboratories of the Metropolitan Area of ​​the Valley of Aburrá. A descriptive cross-sectional study was carried out during, where 14 laboratories were analyzed, Secretaries, laboratory assistants, bacteriologists and physicians. As results, it was obtained that the requests for examinations are made in printed form by the attending physician in 85.7% of the laboratories, verbal requests are not made in 42.9%, the orders are verified with the doctor in the In case of finding an abnormality in the request of the exam 64.3%, the auxiliary staff is given training for the sample 71.4%, and who provides the indications for the analysis is the secretary or receptionist in 42, 9%. 87.55% of the laboratories have a manual for the pre-analytical phase and 71.4% of the auxiliaries knew the manual in the training of sampling. When there is an error in the request for the exams Errors such as patient name are given in 42.9% and verification with patients of the conditions for sampling in 85.7% of laboratories evaluated. It can be evidenced that in the laboratories surveyed the quality conditions in the processes of the pre-analytic phase must be improved since they are not being fulfilled according to the norms established by the Systems of Quality Management.