bluuebunny/crossref_metadata_2025 huggingface dataset:
Reference values for rotational thromboelastometry (ROTEM) in clinically healthy cats
Authors: Marly‐Voquer Charlotte , Riond Barbara , Jud Schefer Rahel , Kutter Annette P. N.
Published: February 2017

Objective

To establish reference intervals for rotational thromboelastometry (ROTEM) using feline blood.

Design

Prospective study.

Setting

University teaching hospital.

Animals

Twenty‐three clinically healthy cats between 1 and 15 years.

Intervention

For each cat, whole blood was collected via jugular or medial saphenous venipuncture, and blood was placed into a serum tube, a tube containing potassium‐EDTA, and tubes containing 3.2% sodium citrate. The tubes were maintained at 37°C for a maximum of 30 minutes before coagulation testing.

Measurements and Main Results

ROTEM tests included the EXTEM, INTEM, FIBTEM, and APTEM assays. In addition, prothrombin time, activated partial thromboplastin time, thrombin time, and fibrinogen concentration (Clauss method) were analyzed for each cat. Reference intervals for ROTEM were calculated using the 2.5–97.5th percentile for each parameter, and correlation with the standard coagulation profile was performed. Compared to people, clinically healthy cats had similar values for the EXTEM and INTEM assays, but had lower plasma fibrinogen concentrations (0.9–2.2 g/L), resulting in weaker maximum clot firmness (MCF, 3–10 mm) in the FIBTEM test. In 18 cats, maximum lysis (ML) values in the APTEM test were higher than in the EXTEM test, which seems unlikely to have occurred in the presence of aprotinin. It is possible that the observed high maximum lysis values were due to clot retraction rather than true clot lysis. Further studies will be required to test this hypothesis.

Conclusions

Cats have a weaker clot in the FIBTEM test, but have a similar clot strength to human blood in the other ROTEM assays, which may be due to a stronger contribution of platelets compared to that found in people. In cats, careful interpretation of the results to diagnose hyperfibrinolysis is advised, especially with the APTEM test, until further data are available.
High Quality Liquid Sukūk: Relevance, Practice, and Empirical Research in the Context of Rising Global Interest Rates
Authors: Karatas Abdullah
Published: February 2017

Liquidity management has always been a major issue in Islamic banking. In the early years of the industry, a major problem was a general tendency toward excess liquidity. In the future, the main issue in the context of depressed oil prices, a rising global interest-rate environment, and a tightened regulatory landscape under Basel III is likely to be a relative scarcity of high quality liquid assets (HQLA), or high quality liquid sukūk (Note 1). The incoming U.S. Treasury secretary Steven Mnuchin has already indicated that the Trump administration’s plans could rapidly turbocharge the U.S. economy, thereby altering the prevailing low-interest rate dynamic at the U.S. Federal Reserve (“U.S. Fed”), leading many to anticipate higher interest rates (Wigglesworth & Moore, 2016).Among the available liquidity management instruments in Islamic banking, only sukūk of a particular type meet the requirements of HQLA (in principle) as defined by the Basel Committee and adapted for Islamic finance by the IFSB (Islamic Financial Services Board). Candidates for HQLA are only international sukūk, i.e. sukūk that are issued in an international currency, listed, and traded not only locally but also internationally. Sovereigns and international institutions such as the IDB have issued almost all sukūk of this caliber. In this paper, we will make empirically informed qualitative projections on the outlook for HQL (high quality liquid) sukūk in the context of a rising global interest-rate environment.
Does Perception of Business Climate Differ Between Foreign and Local Investors? A Firm-level Study of Transition Economies in Eastern Europe and Central Asia
Authors: Golubeva Olga
Published: February 2017

Difference between foreign and local investors in their respective assessments of business climate constraints has not yet been given much attention in research literature. Drawing on institutional theory and the concept of liability of foreignness (LoF), the study contributes towards filling this gap in the context of business climate variables faced by foreign firms operating in transition economies. The Mann-Whitney U Test is applied to firm-level data of 30 transition economies in Eastern Europe and Central Asia. We found that foreign investors experience less trouble with access to finance, tax rate and competition towards the informal sector compared with domestic firms. Conversely, such variables as courts, custom and trade regulations, inadequate workforce, and labor regulations disturbed foreign investors more than local companies. LoF appears as a balanced outcome of firm-specific advantages, possessed by foreign investors, and location and institutional advantages, utilized by the local companies. The results point towards important possible synergies in enhancing the business climate in transition economies by policy-makers, and to potential conflict between policy reforms accommodating the interests of foreign capital against those of domestic firms.
English Cooperative Learning Mode in a Rural Junior High School in China
Authors: Zhang Haiyan , Peng Wen , Sun Liuhua
Published: February 2017

Cooperative learning is one of the most recognized and fruitful research areas in modern education practice. It has been widely used in many countries as an effective teaching strategy to improve class efficiency and students’ comprehensive language ability since the 1990’s. This paper takes JA Junior High School, a rural junior high school in Nantong, China, as a case to explore its English cooperative learning mode. A questionnaire was designed based on nine factors namely learning expectation, learning interest, learning initiative, emotional experience, cooperative awareness, cooperative ability, learning effectiveness, learning evaluation and English usage level. The purpose is to try to find whether gender, grade and academic achievements have an effect on English cooperative learning. 515 valid questionnaires were collected and analyzed by t-test and One-way ANOVA. After analysis, it turned out that these three factors have an impact on the effectiveness of English cooperative learning. The results showed that the differences of gender, grade and academic achievements should be taken into consideration in accordance with the characteristics of rural middle school in constructing the English cooperative learning mode.
Culture at the Bottom of Startups: Reflections on Social Expectations
Authors: Mendoza Cristian , O. P. Eric Salobir
Published: February 2017

This article aims to define the culture at the bottom of the development of “startup” initiatives (or the startup movement). These are initiatives for improving an organization in three different ways: asking creative groups to collaborate with larger organizations for solving specific problems; inviting creative groups (hubs) into larger institutions for searching new ideas; and setting up collective spaces for the sake of public relations. I aim to define if the promotion of startup initiatives could be adequate for faith-based institutions such as the Catholic Church. Startup hubs are growing faster in our world, due to the common perception of social discomfort in regard to the political, economic or social systems. Not every creative initiative is a startup, as these initiatives aim to improve the system from within, thanks to mutual collaboration. Therefore they require common ground and respect for the principles of the larger body. Most startup hubs refer today to technological development, but some of them aim to enhance collective expectations. Our thesis is that some startup hubs could also be set up for changing personal behaviors. Startup hubs with the scope of changing personal lifestyles could also modify cultural interactions, becoming very attractive for faith-based institutions and also for the Catholic Church.
Examining the Effectiveness of a Rational Emotive Personal-Disclosure Mutual-Sharing (REPDMS) Intervention on the Irrational Beliefs and Rational Beliefs of Greek Adolescent Athletes
Authors: Vertopoulos Evangelos , Turner Martin J.
Published: February 2017

The present study examined the effects of a rational emotive personal-disclosure mutual-sharing (REPDMS) intervention on the rational and irrational beliefs of a group of Greek adolescent athletes that had previously participated in four rational emotive behavior therapy (REBT) educational workshops. Measurements were taken before REBT workshops (baseline), during the REBT workshop period, and after the REPDMS session (postintervention). Further, a comparison group received REBT education, but did not receive REPDMS, allowing the between-subjects comparison between participants who received REPDMS and participants who did not. Findings support the hypotheses that REPDMS has positive effects on further reducing irrational beliefs, enhancing rational beliefs, and prolonging the duration of these positive effects, over and above REBT education alone. Qualitative inspection of the REPDMS transcript also revealed participant perceptions of REBT, and served to stimulate critical author reflections on REPDMS.
Lymphomatoid granulomatosis with pulmonary and gastrointestinal involvement
Authors: Kappen J H , van Zaanen H C T , Snelder S M , van Tilburg A J P , Rudolphus A
Published: February 2017

We present a rare case of grade II lymphomatoid granulomatosis (LYG) with pulmonary and gastrointestinal involvement. LYG is considered an Epstein-Barr virus-driven lymphoproliferative disorder that often presents with multiple nodular lesions in the lungs and sometimes involvement of skin and the central nervous system. Although the aetiology is unknown, it is associated with the use of immunosuppressives. Involvement of other organ systems is very rare. We successfully treated our patients with 6 cycles of R-CHOP and autologous stem cell transplantation with a major response at 20 months follow-up.
Biotic responses to multiple aquatic and terrestrial gradients in shallow subarctic lakes (Old Crow Flats, Yukon, Canada)
Authors: Balasubramaniam A.M. , Medeiros A.S. , Turner K.W. , Hall R.I. , Wolfe B.B.
Published: February 2017

Biotic communities in shallow northern lakes are frequently used to assess environmental change; however, complex interactions among multiple factors remain understudied. Here, we present analyses of a comprehensive data set that evaluates the influence input waters, catchment characteristics, limnology, and sediment properties on diatom and chironomid assemblages in surface sediments of ~49 shallow mainly thermokarst lakes in Old Crow Flats, Yukon. Multivariate analyses and ANOSIM tests identified that composition of diatom (119 taxa) and chironomid (68 taxa) assemblages differs significantly (p < 0.05) between lakes with snowmelt- versus rainfall-dominated input water. Redundancy analyses revealed strong correlation of limnological, sediment, and catchment variables with input waters. Variation partitioning analyses showed that unique effects of limnological variables account for the largest proportion of variation in diatom and chironomid assemblages (17.2% and 12.6%, respectively). Important independent roles of sediment properties (8.5% and 9.5%) and catchment characteristics (4.9% and 5.1%) were also identified. We suggest that the substantial variation shared among these classes (6.1% and 7.9%) is largely attributable to hydrological processes. Our study demonstrates the utility of multi-factor analysis in northern aquatic research and draws attention to the limitations of one-dimensional comparisons and their interpretations when modelling biotic responses to environmental change.
Finnish botanists and mycologists in the Arctic
Authors: Väre Henry
Published: February 2017

Finnish botanists and mycologists have studied Arctic areas and timberline regions since the beginning of the 18th century. Most expeditions to the Kola Peninsula were made between 1800 and 1917 and until 1945 to Lapponia petsamoënsis on the western rim of the Kola Peninsula. Since those years, these areas have been part of the Soviet Union or Russia. Svalbard and Newfoundland and Labrador have been studied repeatedly as well, Svalbard since the 1860s and Newfoundland and Labrador since the 1930s. This article focuses on Finnish collections. These are deposited in the herbaria of Helsinki, Turku, and Oulu universities, except materials from the Nordenskiöld expeditions, which were mainly deposited in Stockholm. Concerning the Kola Peninsula, collections at Helsinki are the most extensive. The exact number of specimens is not known, but by rough estimation, the number is about 60 000, with an additional 110 000 observations included in the database. These expeditions have provided material to describe 305 new taxa to science, viz. 47 algae, 78 bryophytes, 25 fungi, 136 lichens, and 19 vascular plants. This number is an underestimate, as many new species have been described in several separate taxonomic articles. At least 63 persons have contributed to making these collections to Finnish herbaria. Of those, 52 are of Finnish nationality.
Seismic performance of soil-nailed walls using a 1g shaking table
Authors: Yazdandoust Majid
Published: February 2017

To assess the seismic performance of soil-nailed walls, a series of 1g shaking table tests was conducted on 0.8 m high wall models with different nail lengths. It was found that the seismic deformation mode of walls highly depends on the nail length and input motion parameters. The combination of a base sliding and rotating deformation mode was observed as the predominant mode of deformation and the length to height (L/H) ratio of 0.7 was presented as the critical ratio in seismic conditions. The pattern of the observed failure mechanisms was similar to a third-degree polynomial failure surface with a specific inflection point. Irrespective of different nail lengths, the threshold acceleration corresponding to the onset of plastic displacements was similar and equal to 0.5g for all models. Based on the formation of initial cracks, a range of Δx/H = 0.33%–0.56% (where Δx is the lateral displacement of the facing) was found as a transitional level from quasi-elastic to plastic state. Also, based on the initial development of the active wedge failure, a range of Δx/H = 3.3%–4.3% was found as a transitional level from plastic to failure state.
Spatial mismatch between sea lamprey behaviour and trap location explains low success at trapping for control
Authors: Rous Andrew M. , McLean Adrienne R. , Barber Jessica , Bravener Gale , Castro-Santos Theodore , Holbrook Christopher M. , Imre Istvan , Pratt Thomas C. , McLaughlin Robert L.
Published: February 2017

Crucial to the management of invasive species is understanding space use and the environmental features affecting space use. Improved understanding of space use by invasive sea lamprey (Petromyzon marinus) could help researchers discern why trap success in large rivers is lower than needed for effective control. We tested whether manipulating discharge nightly could increase trap success at a hydroelectric generating station on the St. Marys River. We quantified numbers of acoustically tagged sea lampreys migrating up to, and their space use at, the hydroelectric generating station. In 2011 and 2012, 78% and 68%, respectively, of tagged sea lampreys reached the generating station. Sea lampreys were active along the face, but more likely to occur at the bottom and away from the traps near the surface, especially when discharge was high. Our findings suggest that a low probability of encountering traps was due to spatial (vertical) mismatch between space use by sea lamprey and trap locations and that increasing discharge did not alter space use in ways that increased trap encounter. Understanding space use by invasive species can help managers assess the efficacy of trapping and ways of improving trapping success.
Thermal consequences of subterranean nesting behavior in a prairie-dwelling turtle, the Ornate Box Turtle (Terrapene ornata)
Authors: Tucker Charles R. , Strickland Jeramie T. , Delaney David K. , Ligon Day B.
Published: February 2017

Many oviparous reptiles deposit eggs in excavated nest chambers, and the location and depth at which eggs are laid can affect predation risk, incubation duration, mortality rates, and hatchling phenotype. Among turtles, nest depth also influences incubation conditions of some large-bodied species, but nest depth is generally expected to vary less among small-bodied species. We monitored nesting behavior of Ornate Box Turtles (Terrapene ornata (Agassiz, 1857)) for two seasons in Illinois. We used direct observations to confirm that, among 31 nesting events, six females oviposited while beneath the substrate surface. Furthermore, comparisons of body length to nest depth indicated that five additional females likely also constructed nests while buried. Nests laid while females were underground were deeper, on average, than other nests (16.7 versus 11.2 cm), and while mean nest temperatures were similar between groups, temperature fluctuations and maximum temperatures were lower among nests that were laid while females were underground. Subterranean oviposition appears to have moderated incubation temperatures by allowing females to deposit eggs at greater depths than would be possible from the surface. This little-documented behavior may be a mechanism for this species to influence the incubation environment, which in turn may influence hatchling phenotypes.
FRACTAL DIMENSION OF CERTAIN CONTINUOUS FUNCTIONS OF UNBOUNDED VARIATION
Authors: LIANG Y. S. , SU W. Y.
Published: February 2017

Continuous functions on closed intervals are composed of bounded variation functions and unbounded variation functions. Fractal dimension of continuous functions with bounded variation must be one-dimensional (1D). While fractal dimension of continuous functions with unbounded variation may be 1 or not. Certain continuous functions of unbounded variation whose fractal dimensions are 1 have been mainly investigated in the paper. A continuous function on a closed interval with finite unbounded variation points has been proved to be 1D. Furthermore, we deal with continuous functions which have infinite unbounded variation points and part of them have been proved to be 1D. Certain examples of 1D continuous functions which have uncountable unbounded variation points have been given in the present paper.
Optimal Skip Entry Trajectory for Lunar Return Vehicle with Trim‐Flaps
Authors: Wang Yin , Yao Keming
Published: February 2017

A medium lift‐to‐drag ratio lunar return vehicle with trim‐flaps is presented in this paper. The trajectory optimization design under heat‐rate constrain for skip entry lunar return vehicle is analyzed. The optimization problem with a first‐order state constraint is introduced. The trajectory applying the Pontryagin maximum principle under the performance of minimum heat is optimized, and the optimal expression of lift coefficient is derived. The simulation studies show that this research method can decrease the heat‐rate effectively.
Aseptic Abscesses and Inflammatory Bowel Disease: Two Cases and Review of Literature
Authors: Bollegala Natasha , Khan Rishad , Scaffidi Michael A. , Al-Mazroui Ahmed , Tessolini Jenna , Showler Adrienne , Colak Errol , Grover Samir C.
Published: February 2017

Background. Aseptic abscesses (AA) are sterile lesions that represent an extraintestinal manifestation (EIM) of inflammatory bowel disease (IBD). Though Canada has the highest prevalence of IBD in the world, reports of IBD-associated AA are absent in Canada. This may represent a different IBD phenotype or underrecognition and underreporting.Purpose. To explore AA as a possible EIM of IBD and evaluate clinical and investigative findings among patients with IBD-associated AA.Methods. Retrospective chart and literature reviews were performed to find cases of IBD-associated AA at our institution and in the literature.Results. We identified 2 cases of IBD-associated AA in our institution. Both patients had ulcerative colitis and presented with fever, abdominal pain, and weight loss. Radiological workup and aspiration showed sterile splenic abscesses. The AA were unresponsive to antibiotics. One patient improved on corticosteroids and one underwent splenectomy. We retrieved 37 cases of IBD-associated AA from the literature. All patients showed no evidence of infection, failed to resolve with antibiotics, and, if attempted, improved on corticosteroids.Conclusions. Our cases are the first reported in Canada. They support literature which suggests AA as an EIM of IBD and may help increase recognition and reporting of this phenomenon.
Bounds on the Electromagnetic Dipole Moments through the Single Top Production at the CLIC
Authors: Köksal M. , Billur A. A. , Gutiérrez-Rodríguez A.
Published: February 2017

We obtain bounds on the anomalous magnetic and electric dipole moments of thet-quark from a future high-energy and high-luminosity linear electron positron collider, as the CLIC, with polarized and unpolarized electron beams which are powerful tools for determining new physics. We consider the processesγe-→t¯bνe(γis the Compton backscattering photon) ande+e-→e-γ⁎e+→t¯bνee+(γ⁎is the Weizsacker-Williams photon) as they are one of the most important sources of single top quark production. For systematic uncertainties ofδsys=0%  (5%),b-tagging  efficiency=0.8, center-of-mass energy ofs=3 TeV, and integrated luminosity ofL=2ab-1the futuree+e-collider may put bounds on the electromagnetic dipole momentsa^Vanda^Aof the top quark of the order ofO(10-2–10-1)at the2σ  (3σ)level, which are competitive with those recently reported in previous studies at hadron colliders and the ILC.
Perceived Psychological, Economic, and Social Impact of Khat Chewing among Adolescents and Adults in Nekemte Town, East Welega Zone, West Ethiopia
Authors: Wondemagegn Amsalu Taye , Cheme Melese Chego , Kibret Kelemu Tilahun
Published: February 2017

The main aim of this study was to assess psychological, economic, and social impact of khat chewing among adolescents, in Nekemte town, East Welega Zone. A community based cross-sectional study was conducted from March to June 2016 using both quantitative and qualitative methods of data collection. A total of 359 samples were included in the study. A pretested, interviewer based structured questionnaire was employed during data collection. The study found the current prevalence of khat chewing practices was 48.6%. Perceived psychological problems especially depression and anxiety were associated with khat chewing practices. The risk of depression was about 25 times higher among khat chewers compared to nonchewers. Similarly the risk of anxiety among khat chewers was about 5 times higher compared to nonchewers. Generally current khat chewing practices in the study area are relatively high. The occurrence of reported, perceived psychological problems mainly depression and anxiety was significantly higher among khat chewers compared to nonchewers. Thus efforts like creating awareness about negative effect, making different recreation methods available, and formulating common conventions regarding khat use mainly by young generations are necessary to decrease the magnitude of chewing practices and thereby its associated consequences.
On the Development of Focused Ultrasound Liquid Atomizers
Authors: Al-Jumaily Ahmed M. , Meshkinzar Ata
Published: February 2017

This paper reviews the evolution of focused ultrasonic transducers of various kinds for fluid atomization and vaporization. Ultrasonic transducers used for atomization purposes in biomedical, pharmaceutical, or industrial applications, such as surface acoustic wave (SAW) transducers, array of micromachined nozzles, and Fourier horn micromachined nozzles with or without a central channel, are all presented and compared. For simplicity of manufacturing and low cost, we focus on plates and curved and corrugated structures for biomedical humidification.
Pernicious Anemia Associated Cobalamin Deficiency and Thrombotic Microangiopathy: Case Report and Review of the Literature
Authors: Yousaf Farhanah , Spinowitz Bruce , Charytan Chaim , Galler Marilyn
Published: February 2017

A 43-year-old Hispanic male without significant previous medical history was brought to emergency department for syncope following a blood draw to investigate a 40 lbs weight loss during the past 6 months associated with decreased appetite and progressive fatigue. The patient also reported a 1-month history of jaundice. On examination, he was hemodynamically stable and afebrile with pallor and diffuse jaundice but without skin rash or palpable purpura. Normal sensations and power in all extremities were evident on neurological exam. Presence of hemolytic anemia, schistocytosis, thrombocytopenia, and elevated lactate dehydrogenase (LDH) was suggestive of thrombotic thrombocytopenic purpura (TTP). However, presence of leukopenia, macrocytes, and an inadequate reticulocyte response to the degree of anemia served as initial clues to an alternative diagnosis. Two and one units of packed red blood cells were transfused on day 1 and day 3, respectively. In addition, one unit of platelets was transfused on day 2. Daily therapeutic plasma exchange (TPE) was initiated and continued until ADAMTS-13 result ruled out TTP. A low cobalamin (vitamin B12) level was evident at initial laboratory work-up and subsequent testing revealed positive intrinsic factor-blocking antibodies supporting a diagnosis of pernicious anemia with severe cobalamin deficiency. Hematological improvement was observed following vitamin B12 supplementation. The patient was discharged and markedly improved on day 9 with outpatient follow-up for cobalamin supplementation.
Clinical Analysis of Algerian Patients with Pompe Disease
Authors: Sifi Y. , Medjroubi M. , Froissart R. , Taghane N. , Sifi K. , Benhabiles A. , Lemai S. , Semra S. , Benmekhebi H. , Bouderda Z. , Abadi N. , Hamri A.
Published: February 2017

Pompe’s disease is a metabolic myopathy caused by a deficiency of acid alpha-glucosidase (GAA), also called acid maltase, an enzyme that degrades lysosomal glycogen. The clinical presentation of Pompe’s disease is variable with respect to the age of onset and rate of disease progression. Patients with onset of symptoms in early infancy (infantile-onset Pompe disease (IOPD)) typically exhibit rapidly progressive hypertrophic cardiomyopathy and marked muscle weakness. Most of them die within the first year of life from cardiac and/or respiratory failure. In the majority of cases of Pompe’s disease, onset of symptoms occurs after infancy, ranging widely from the first to sixth decade of life (late-onset Pompe’s disease or LOPD). Progression of the disease is relentless and patients eventually progress to loss of ambulation and death due to respiratory failure. The objective of this study was to characterize the clinical presentation of 6 patients (3 with EOPD and the other 3 with LOPD) of 5 families from the East of Algeria. All our patients were diagnosed as having Pompe’s disease based on biochemical confirmations of GAA deficiency by dried blood spots (DBS) and GAA gene mutations were analyzed in all patients who consented (n=4). Our results are similar to other ethnic groups.
The Dispersion Rule of Fragments about the Asymmetric Shell
Authors: Ding Liangliang , Li Zhenduo , Liang Minzu , Li Xiangyu , Lu Fangyun
Published: February 2017

In order to obtain the dispersion rule of fragments about the asymmetric shell subjected to internal blast loading, two different cross section structures, concave-shaped and convex-shaped, were carried out by experimental and numerical methods. The simulation results well coincided with the experimental results, and the spatial distribution and fragment velocity were obtained. The optimal curvatures for the different concave structures changed from 4r to 6r (r represents the charge radius), as the central angle of concave structure changed from 90° to 120°. However, the optimal curvature changed weakly when the central angle of concave structure was larger than 120°. In addition, a formula which can rapidly predict the projection angle range was fitted for the convex structure. The conclusions can provide a reference for concave-shaped and convex-shaped structures to achieve a higher effectiveness of fragments.
ІНФЕКЦІЙНІ ЧИННИКИ У ФОРМУВАННІ ТЕРАПЕВТИЧНОЇ ПАТОЛОГІЇ ПІДШЛУНКОВОЇ ЗАЛОЗИ
Authors: Shayhen O. R. , Babinets L. S.
Published: February 2017

У статті проаналізовано літературні джерела, в яких висвітлено роль інфекції у виникненні панкреатиту. Враховуючи різноманітність чинників формування хронічного панкреатиту, припускається поєднане ушкодження підшлункової залози кількома факторами одночасно.
ВІДМІННОСТІ ПРОЯВІВ ДЕПРЕСИВНИХ РОЗЛАДІВ У ЕМІГРАНТІВ З УРАХУВАННЯМ ГЕНЕЗУ ПАТОЛОГІЇ (ПСИХОГЕННОГО, ЕНДОГЕННОГО, ОРГАНІЧНОГО)
Authors: Venger O. P.
Published: February 2017

Проведене дослідження соціально-психологічних, феноменологічних, клініко-психопатологічних відмінностей депресивних розладів у емігрантів з урахуванням ґенезу патології органічного, ендогенного та психогенного характеру. Використано клініко-психопатологічний, психометричний, статистичний методи. Нами обстежено 198 емігрантів  (осіб, які постійно, щонайменше протягом останнього року, проживали за межами України і на момент обстеження тимчасово перебували в Україні та планували найближчим часом повернутися за кордон) яким встановлено остаточний клінічний діагноз депресивного розладу відповідно до критеріїв МКХ-10. Ми виділили три клінічні групи емігрантів, хворих на психогенні депресивні розлади, ендогенні  та органічні. Психометричне дослідження виявило у емігрантів, хворих на депресивні розлади, виражені ознаки депресивного настрою; їм притаманні прояви адинамічної, ажитованої депресії та депресії зі страхом, причому найважчими ці прояви є у хворих на органічні та ендогенні депресії. Високий рівень депресії поєднується у емігрантів з вираженими ознаками тривоги, як психічної, так і соматичної; ці прояви також найбільш виражені у емігрантів, хворих на органічні та ендогенні депресивні розлади. Суїцидальні спроби найрідше скоювали емігранти, хворі на психогенну депресію (2,9 %). Оцінка суїцидального ризику виявила, що емігрантам притаманний суїцидальний ризик середнього ступеня.
ПЕРЕБУДОВА ХІМІЧНОГО СКЛАДУ КІСТКОВОЇ ТКАНИНИ У ВІКОВОМУ АСПЕКТІ ЗА РІЗНИХ РЕЖИМІВ РУХОВОЇ АКТИВНОСТІ
Authors: Davybida N. O. , Bezpalova N. M. , Novakova L. V. , Rutska A. V.
Published: February 2017

Глибоке вивчення процесів перебудови кісткової тканини, її будови, хімічного складу, адаптаційних можливостей є необхідною умовою виявлення закономірностей впливу праці, спорту та ряду професій, що виникають у зв’язку з науково-технічним прогресом, на організм. Моделювання різних режимів рухової активності не в повній мірі відповідає тренувальним процесам людини у фізичній культурі та спорті. Однак результати, отримані при даному експериментальному дослідженні, мають відношення до розкриття загальнобіологічних закономірностей, що ґрунтуються на індивідуальних і генетично обумовлених особливостях індивідуумів, знання котрих послужить морфологічним обґрунтуванням тренувального процесу і прогнозуванню структурних перетворень в скелеті при різних режимах рухової активності, запобіганню травм та розвитку остеопорозу.
ДИНАМІКА ІНДЕКСУ РЕЗИСТЕНТНОСТІ ТЕСТИКУЛЯРНОЇ АРТЕРІЇ У ХЛОПЧИКІВ З ПАХОВИМИ ГРИЖАМИ, ПРООПЕРОВАНИХ ЛАПАРОСКОПІЧНИМ АБО ТРАДИЦІЙНИМ МЕТОДОМ
Authors: Zakharko V. P.
Published: February 2017

Проведено ультразвукове дослідження інтратестикулярного кровотоку у 98 хлопчиків віком від 6 місяців до 12 років з паховими грижами до оперативного втручання та на 7, 14, 30 доби і 6 місяців після оперативного втручання, проведеного лапароскопічним або традиційним методом. Ми використовували клінічне значення індексу резистентності (IR) тестикулярної артерії, який вимірювали за допомогою доплерографії, як предиктора тестикулярної ішемії. У ході моніторингу ми спостерігали високу позитивну динаміку у хворих, оперованих лапароскопічним методом (PIRS). Знайдено, що індекс резистентності в молодшій, середній і старшій групах хлопчиків оперованих лапароскопічно (підгрупа А) був значно нижчим, ніж у групі оперованих традиційним методом.
ДІАГНОСТИКА СИНДРОМУ ПРОФЕСІЙНОГО ВИГОРАННЯ ЛІКАРІВ БАГАТОПРОФІЛЬНОГО ЗАКЛАДУ ОХОРОНИ ЗДОРОВ’Я
Authors: Mazepa Yu. S. , Pishchikov V. A. , Sydorenko O. O.
Published: February 2017

У статті надається стислий теоретичний огляд проблеми професійного вигорання, висвітлюються його структура, форми впливу на психосоматичне здоров’я працівників (з виділенням професій, які знаходяться в групі ризику) та ефективність їхньої праці, визначені можливі наслідки. Також у статті описані результати проведеного дослідження серед лікарів багатопрофільного закладу охорони здоров’я з детальним поясненням отриманих результатів.
ІМУННІ ПОРУШЕННЯ В ГОСТРОМУ ПЕРІОДІ ЛАКУНАРНОГО ІНСУЛЬТУ
Authors: Salii M. I.
Published: February 2017

Дослідили стан клітинної та гуморальної ланок імунітету у 45 хворих в гострому періоді лакунарного інсульту. Для гострого періоду ЛІ характерними є ознаки дизрегуляції та дефіциту клітинної ланки імунітету і активація гуморальної. Зміни в гуморальній ланці імунітету мали більш виражений характер та відповідали ІІ (Ig G) та ІІІ (Ig M та Ig A) ступеням імунних зрушень. Встановлено кореляцію між рівнем CD16+ та тяжкістю інсульту за шкалою NIHSS (r=0,50, p=0,014).
ПРОГРАМА ПСИХОЛОГІЧНОЇ ДОПОМОГИ ПІДЛІТКАМ ІЗ ВРОДЖЕНИМИ ВАДАМИ СЕРЦЯ
Authors: Sydorenko А. Yu.
Published: February 2017

У статті представлена схема та принципи психологічної допомоги підліткам із вродженими вадами серця (ВВС). У дослідженні взяли участь 25 підлітків з ВВС віком 13 – 15 років, з підвищеним у них рівнем тривоги, ознаками депресії та слабким почуттям когеренції. Психокорекційні заходи охоплювали від 5 до 10 індивідуальних консультацій з підлітками та окремо з батьками. Психокорекційна програма складалась з елементів раціональної та когнітивно-біхевіоральної терапії, включала розбір складних життєвих та клінічних ситуацій (кейсів), аутогенне тренування та елементи кардіо- та психоосвіти. Програма виявилась ефективною у всіх підлітків з ВВС – вдалося нормалізувати рівень тривожності та у переважної більшості ліквідувати ознаки депресії. Крім того, протягом півроку вдалось сприяти розвитку та підвищенню почуття когеренції серед підлітків з ВВС.
ОБҐРУНТУВАННЯ ШЛЯХІВ ПОДОЛАННЯ ДИТЯЧИХ ВІРУСНИХ ІНФЕКЦІЙ В УКРАЇНІ
Authors: Fedyak I. O. , Ivanyulyk І. І. , Mateyko H. B. , Tomashivska T. V. , Brovinska L. M. , Kaminska T. M. , Rozhnova H. S.
Published: February 2017

У статті представлено результати проведеного анкетування лікарів (дитячих інфекціоністів та педіатрів) щодо питань протидії розповсюдженню в Україні вакцинокерованих дитячих вірусних інфекцій. Спеціалістами окреслено основні іміджеві та фінансові проблеми процесу вакцинації, надана оцінка поточного стану його фармацевтичного забезпечення і запропоновано варіанти подолання цих хвороб. Так, на думку лікарів, значне їх поширення в Україні, окрім власне відсутності вакцин, зумовлене відмовою батьків від вакцинації (40 %) та формуванням ЗМІ негативної думки щодо користі імунопрофілактики (35 %). Потребує підняття самооцінка ролі лікаря у схилянні батьків на користь щеплень, а роль провізорів – гарантоване забезпечення якості та наявності вакцин. Залишається проблемою доступність та своєчасність доказової інформації щодо питань профілактики, лікування та протидії розповсюдженню дитячих вірусних інфекцій, оскільки 58 % спеціалістів вважають, що їхня потреба в інформації задоволена частково.
PRIMARY HEALTH CARE DEVELOPMENT IN GEORGIA
Authors: Jugheli K.
Published: February 2017

У статті висвітлено основні питання організації медичної освіти, підготовки кадрів для первинної медичної допомоги в умовах системи реформування охорони здоров’я.
ДЕЯКІ ВЛАСТИВОСТІ ГЕКСАФТОРОСИЛІКАТІВ 3,5-ДИЗАМІЩЕНИХ ПОХІДНИХ 1,2,4-ТРИАЗОЛУ
Authors: Shyshkin I. O. , Anisimov V. Yu. , Gelmboldt V. O.
Published: February 2017

З використанням методу фотоколориметрії проведено визначення ступеня гідролізу гексафторосилікатів 3,5-дизаміщених похідних 1,2,4-триазолу в 1×10-4 М водних розчинах їх солей. Встановлено, що ступінь гідролізу солей змінюється в межах 63,8 – 92,0 %. Знайдено розчинність їх солей у воді, яка становить ≤ 0,0002 мол. %.
МЕТОДОЛОГІЯ ОПЛАТИ ПРАЦІ В ДЕРЖАВНИХ ЗАКЛАДАХ ОХОРОНИ ЗДОРОВ’Я
Authors: Komar A. V. , Krychkovska A. M. , Zayarnyuk N. L. , Khomenko A. І. , Novikov V. P.
Published: February 2017

Досліджено основні аспекти організації обліку видатків на оплату праці в державних закладах охорони здоров’я на підставі діючого нормативно-правового забезпечення. Розглянуто організацію обліку видатків медичного закладу на основну, додаткову зарплату та інші компенсаційні, заохочувальні виплати в системі рахунків бюджетного обліку.
КЛІНІКО-ЕКОНОМІЧНИЙ АНАЛІЗ ВИТРАТ НА ФАРМАКОТЕРАПІЮ ГОСТРОГО ТОНЗИЛІТУ В УМОВАХ СТАЦІОНАРУ
Authors: Masheiko A. M. , Makarenko O. V. , Mavrutenkov V. V.
Published: February 2017

У статті наведено результати інтегрованого частотного^ЕМАВС-аналізу доцільності фінансових витрат на проведення фармакотерапії гострого тонзиліту. Встановлено суттєву перевагу частоти лікарських призначень другорядних засобів (^ над життєво важливими (V) у кількісному вираженні та незначну перевагу життєво важливих засобів над другорядними у вартісному вираженні. З отриманих результатів можна зробити висновок, що основні фінансові кошти не витрачались на необхідні та важливі лікарські засоби для лікування гострого тонзиліту.
CURRENT ECOMOMICAL, SOCIAL ASPECTS OF HEALTH TECHNOLOGIES FOR PRETERM BIRTH AND REAL WORLD DATA OF DRUG PRESCRIPTIONS IN UKRAINE
Authors: Maksymovych Н. М. , Zalis'ka O. M. , Mudrak I. H.
Published: February 2017

Поліпшення якості життя, здоров'я вагітних жінок та лікування передчасних пологів є основними цілями директив ВООЗ. Україна займає 72 місце в рейтингу за рівнем забезпечення материнства в світі.Нами вивчені у порівняльному плані рекомендації ВООЗ, 2015 міжнародні рекомендації, накази МОЗ України щодо лікування передчасних пологів (ПП) та виявлено певні відмінності, що вимагає оновлення вітчизняних протоколів.Ми проаналізували реальні дані частоти призначень лікарських засобів при ПР з використанням АВС^Е^аналізу на основі 102 історій хвороб вагітних жінок з діагнозом відповідно до МКХ-10 - 047.0. Встановлено, що для лікування загрози ПП призначалися 75 торгових назв (46 МНН лікарських засобів та 2 БАД). Сумарно було 689 призначень ліків, що в середньому складає 6,75 препарата на одну вагітну жінку, що свідчить про поліпрагмазію. Виявлено, що в групі А найбільш часто призначаються препарати 7 МНН (14,58 % від загального обсягу) і основним лікарським засобом є натрію хлорид, що свідчить про недостатньо раціональне використання фінансових коштів пацієнтів.Встановлено, що сумарно витрати на призначені ЛЗ при ПР становили 75354,3 грн, а витрати на фармакотерапії 1 пацієнтки були в середньому 740,2 грн.Нами проаналізовані доказові дані про призначення прогестеронів для лікування ПР. Встановлено, що найбільш ефективним для лікування ПП за даними доказової фармації є прогестерон у лікарській формі для вагінального прийому для жінок з короткою шийкою матки, а дигістростерон - при застосуванні допоміжних репродуктивних технологійДоцільною є оптимізація фармацевтичної допомоги вагітним при ПР за даними доказової фармації та призначення економічно ефективної фармакотерапії для раціоналізації витрат пацієнтів.
ПІДХОДИ ЩОДО РОЗРОБКИ МОДЕЛІ ФУНКЦІОНУВАННЯ АГЕНТСТВ З ОЦІНКИ МЕДИЧНИХ ТЕХНОЛОГІЙ В УКРАЇНІ
Authors: Fedyak I. O. , Maksymenko О. V.
Published: February 2017

У статті висвітлено різні погляди трактування поняття «оцінка медичних технологій»; обґрунтовано актуальність та своєчасність створення агентств з HTA в Україні на національному, регіональному та локальному рівнях і запропоновано підходи щодо розробки моделі їх функціонування. Ці підходи доцільно розглядати у площині перетину психологічних, соціальних, законодавчих, організаційних, ринкових аспектів захисту інтересів окремої людини і суспільства в цілому.
СУЧАСНИЙ СТАН СТВОРЕННЯ, ВИРОБНИЦТВА ТА ДОСЛІДЖЕННЯ ТАБЛЕТОВАНИХ ЛІКАРСЬКИХ ПРЕПАРАТІВ. Повідомлення 26. Таблетки для розжовування: характеристика, класифікація, методи одержання, допоміжні речовини при виробництві таблеток для розжовування
Authors: Beley N. M. , Нroshovyi T. A. , Beley S. Ya.
Published: February 2017

У статті наведено результати літературного огляду щодо особливостей виробництва таблеток для розжовування.
Management of Patients on Non–Vitamin K Antagonist Oral Anticoagulants in the Acute Care and Periprocedural Setting: A Scientific Statement From the American Heart Association
Authors: Raval Amish N. , Cigarroa Joaquin E. , Chung Mina K. , Diaz-Sandoval Larry J. , Diercks Deborah , Piccini Jonathan P. , Jung Hee Soo , Washam Jeffrey B. , Welch Babu G. , Zazulia Allyson R. , Collins Sean P.
Published: February 2017

Non–vitamin K oral anticoagulants (NOACs) are now widely used as alternatives to warfarin for stroke prevention in atrial fibrillation and management of venous thromboembolism. In clinical practice, there is still widespread uncertainty on how to manage patients on NOACs who bleed or who are at risk for bleeding. Clinical trial data related to NOAC reversal for bleeding and perioperative management are sparse, and recommendations are largely derived from expert opinion. Knowledge of time of last ingestion of the NOAC and renal function is critical to managing these patients given that laboratory measurement is challenging because of the lack of commercially available assays in the United States. Idarucizumab is available as an antidote to rapidly reverse the effects of dabigatran. At present, there is no specific antidote available in the United States for the oral factor Xa inhibitors. Prothrombin concentrate may be considered in life-threatening bleeding. Healthcare institutions should adopt a NOAC reversal and perioperative management protocol developed with multidisciplinary input.
An Overview of Drought Monitoring and Prediction Systems at Regional and Global Scales
Authors: Hao Zengchao , Yuan Xing , Xia Youlong , Hao Fanghua , Singh Vijay P.
Published: February 2017

In past decades, severe drought events have struck different regions around the world, leading to huge losses to a wide array of environmental and societal sectors. Because of wide impacts of drought, it is of critical importance to monitor drought in near–real time and provide early warning. This article provides an overview of the development of drought monitoring and prediction systems (DMAPS) at regional and global scales. After introducing drought indicators, drought monitoring (based on different data sources and tools) is summarized, along with an introduction of statistical and dynamical drought prediction approaches. The current progress of the development and implementation of DMAPS with various indicators at different temporal and/or spatial resolutions, based on the land surface modeling, remote sensing, and seasonal climate forecast, at the regional and global scales is then reviewed. Advances in drought monitoring with multiple data sources and tools and prediction from multimodel ensembles are highlighted. Also highlighted are challenges and opportunities, including near-real-time and long-term data products, indicator linkage to impacts, prediction skill improvement, and information dissemination/communication. The review of different components of these systems will provide useful guidelines and insights for the future development of effective DMAPS to aid drought modeling and management.
Comment on “Using an ADCP to Estimate Turbulent Kinetic Energy Dissipation Rate in Sheltered Coastal Waters”
Authors: Gargett Ann E.
Published: February 2017

Greene et al. revisit the suggestion that the turbulent kinetic energy dissipation rate could be estimated through a “large-eddy estimate,” employing acoustic measurements of velocity fields associated with the largest energy-containing scales of ocean turbulence. While the large-eddy estimate as originally proposed used vertical velocity and a vertical eddy length scale, Greene et al. chose instead to substitute a horizontal length scale for the latter. This comment argues that combining a horizontal scale for length with a vertical velocity scale produces a large-eddy estimate of the dissipation rate that is accurate only if the energy-containing eddies are isotropic, and that this condition is highly unlikely in naturally occurring ocean turbulence, subject as it is to influences of stratification, vertical shear, and/or the presence of horizontal boundaries. The problem is documented using data from a large-eddy simulation of Langmuir supercells.
Simultaneous Linking of Cross-Informant and Longitudinal Data Involving Positive Family Relationships
Authors: Preston Kathleen Suzanne Johnson , Gottfried Allen W. , Park Jonathan J. , Manapat Patrick Don , Gottfried Adele Eskeles , Oliver Pamella H.
Published: February 2017

Measurement invariance is a prerequisite when comparing different groups of individuals or when studying a group of individuals across time. This assures that the same construct is assessed without measurement artifacts. This investigation applied a novel approach of simultaneous parameter linking to cross-sectional and longitudinal measures of the construct of positive family relationships. Previously, a scale to measure this construct in mothers was developed longitudinally using the nominal response model of item response theory. In this study, this methodology was conducted for the first time to develop such a scale for children. The data for both informants derived from the Fullerton Longitudinal Study and encompassed 9 annual assessments spanning 8-years (age 9-17 years). This permitted linking across informants studied concurrently and prospectively. This procedure minimized measurement error, furnished a common metric across informants and time and established measurement invariance. Resulting thetas revealed a significant degree of concordance between informants across assessment waves as well as stability of individual differences for both informants over time. This psychometric investigation is unique because it simultaneously established invariance of a construct across informants and time. Implications for future research are discussed.
Raccontare la totalità. Uomini Contro di Francesco Rosi
Authors: Cangiano Mimmo
Published: February 2017

Il saggio si concentra sull’analisi del film Uomini contro (1970) di Francesco Rosi, analizzandolo nell’ottica lukácsiana dei concetti di totalità, tipico e realismo. L’autore intende dimostrare come Rosi, nella sua ‘rilettura’ di Un anno sull’altipiano di Emilio Lussu, abbia portato in gioco una peculiare interpretazione marxista tanto della Grande Guerra quanto del mezzo cinematografico come strumento adatto a fornire un’interpretazione di classe delle numerose relazioni sociali, politiche, economiche che attraversavano il Paese al tempo. Si dimostra poi come Rosi abbia inoltre connesso l’interpretazione dell’evento storico determinato ad una più generale lettura incentrata sugli effetti del primo conflitto mondiale sia nel rapporto di questo con l’Italia del primo ’900, sia con gli sviluppo storici (in particolare il Fascismo) successivi. Rispetto al libro di Lussu, il film di Rosi si caratterizzerebbe dunque non tanto per il suo essere uno riscrittura ‘attualizzante’ (sullo sfondo del ’68 e della guerra in Vietnam) di Un anno sull’altipiano, ma una riscrittura tesa a esaminare il conflitto mondiale (e le interpretazioni ideologiche di questo, Lussu compreso) tanto nell’ottica dialettica del momento storico determinato (rapporto della Grande Guerra con le necessità industriali italiane, ruolo degli intellettuali interventisti, crollo dell’Internazionale socialista, ecc.), quanto momento cardine degli sviluppi successivi del conflitto di classe.