bluuebunny/crossref_metadata_2025 huggingface dataset:
Stable factorization for phase factors of quantum signal processing
Authors: Ying Lexing
Published: October 2022

This paper proposes a new factorization algorithm for computing the phase factors of quantum signal processing. The proposed algorithm avoids root finding of high degree polynomials by using a key step of Prony's method and is numerically stable in the double precision arithmetics. Experimental results are reported for Hamiltonian simulation, eigenstate filtering, matrix inversion, and Fermi-Dirac operator.
Severe pulmonary edema following hyperbaric oxygen therapy for acute carbon monoxide poisoning: a case report and clinical experience
Authors:   Department of Hyperbaric Oxygen, Navy General Hospital, PR China, Fan Danfeng , Lv Yan , Hu Huijun , Pan Shuyi
Published: October 2022

Purpose: Pulmonary edema following hyperbaric oxygen (HBO2) therapy is a rare clinical phenomenon. This case report describes such a patient – a 56-year-old woman who suffered from severe pulmonary edema after HBO2 therapy for carbon monoxide (CO) poisoning. Case: Patient experienced ecphysesis and dyspnea suddenly after HBO2 therapy (100% oxygen at 0.25 MPa, for 60 minutes with a five-minute air break and decompression at 0.01 MPa/minute). Post therapy her heart rate (HR), blood pressure (BP), respiratory rate (RR) and oxygen saturation (SO2) were 140 bpm, 60/40 mmHg, 38 bpm and 84%, respectively. Diagnoses of acute pulmonary edema and shock were made. Various treatments including antishock, tracheal intubation, mechanical ventilation for respiratory support, a diuretic, dexamethasone, asthma relief, and acidosis correction were administered. Pulmonary computed tomography (CT) indicated significant pulmonary edema. Due to active treatment, the patient showed gradual improvement. Pulmonary CT re-examination showed pulmonary edema markedly improved. At the two-year follow-up, the patient reported no abnormal mental or neurological symptoms. Conclusion: Acute pulmonary edema is rare but can lead to serious side effects of HBO2 therapy in patients with severe acute CO poisoning. This complication must be must considered when administering HBO2 therapy to patients with severe CO poisoning.
Swimming-induced pulmonary edema in a tropical climate: a case report
Authors:   AFPN 6060, Changi Naval Base, Singapore, Kwek WMJ , Chow W
Published: October 2022

Purpose: Pulmonary edema following hyperbaric oxygen (HBO2) therapy is a rare clinical phenomenon. This case report describes such a patient – a 56-year-old woman who suffered from severe pulmonary edema after HBO2 therapy for carbon monoxide (CO) poisoning.  Case: Patient experienced ecphysesis and dyspnea suddenly after HBO2 therapy (100% oxygen at 0.25 MPa, for 60 minutes with a five-minute air break and decompression at 0.01 MPa/minute). Post therapy her heart rate (HR), blood pressure (BP), respiratory rate (RR) and oxygen saturation (SO2) were 140 bpm, 60/40 mmHg,  38 bpm and 84%, respectively. Diagnoses of acute pulmonary edema and shock were made.  Various treatments including antishock, tracheal intubation, mechanical ventilation for respiratory support, a diuretic, dexamethasone, asthma relief, and acidosis correction were administered. Pulmonary computed tomography (CT) indicated significant pulmonary edema. Due to active treatment, the patient showed gradual improvement. Pulmonary CT re-examination showed pulmonary edema markedly improved. At the two-year follow-up, the patient reported no abnormal mental or neurological symptoms.  Conclusion: Acute pulmonary edema is rare but can lead to serious side effects of HBO2 therapy in patients with severe acute CO poisoning. This complication must be must considered when administering HBO2 therapy to patients with severe CO poisoning.
Cost Analysis of Antipsychotics Schizophrenia of Inpatients in Mental Hospital West Java Province
Authors: Kurnia Utami Indah , Barliana Melisa I. , Halimah Eli
Published: October 2022

Schizophrenia is a mental disorder that can affect behavior, emotions and communication. In the agitation phase ithe patient is acompanied by destructive or violent behavior. In these conditions, the patient must immediately calm down to avoid risk. Monotherapy Treatment in acute agitation schizophrenia is recommended than combination therapy. The purpose of this study was to determine the effectiveness of treatment costs and the factors that influence the total cost of schizophrenia patients at the Mental Hospital of West Java Province. This study was observational by cross sectional study design according to the hospital perspective. This method is retrospective data. The subject were inpatients aged 18-65 years with diagnosis of schizophrenia disorder and receiving antipsychotic therapy for at least 1 month. The results showed that average cost-effectiveness ratio (ACER) Rp.288.659/ 1 score PANSS EC with an average decrease score of 9,70. There is a difference in variant data compared because p-value = 0.011<0,05. ICER calculation of A to C = (Rp. 2.800.001–Rp. 2.593.821) / (9.70 - 8.57) = Rp. 182.460. The factors that influence the total cost found that the most significant are administration and room. The conclusion is atypical-atypical monotherapy recommended as a treatment for schizophrenic in agitation acute.
PAIN MITIGATION AND MANAGEMENT STRATEGIES FOR ANTI-GD2 INFUSIONS
Authors: Morgenstern Daniel , Nysom Karsten , Morad Andrea Gomez , Rafael Margarida Simão , Zier Judith , Marachelian Araz , Watt Tanya
Published: October 2022

Monoclonal antibodies (mAbs) targeting disialoganglioside 2 (GD2) are an
important treatment advance for high-risk neuroblastoma, including in
patients with refractory or relapsed disease. Dinutuximab and
dinutuximab beta are administered for ≥8 hours (and up to 10 days for
dinutuximab beta), whereas naxitamab is administered over 0.5 to 2 hours
as tolerated. As acute pain is a class effect of anti-GD2 mAbs,
effective pain management is crucial to successful treatment. Here, we
provide an overview of current pain-management strategies for anti-GD2
mAb infusions, including discussion of opioid analgesics, ketamine,
gabapentin, and other similar agents, and non-pharmacologic approaches.
Potential future pain management options are also discussed, in addition
to the use of sedatives to reduce the anxiety that may be associated
with infusion-related pain. Specific guidance for pain management during
naxitamab infusions is provided, as these infusions are administered
over 0.5 to 2 hours and may not need overnight hospitalization based on
the physician’s assessment, and require rapid-onset analgesia options
suitable for potential outpatient administration.
Seizures in Activating Calcium Sensing Receptor Antibodies Positive Autoimmune Hypoparathyroidism & Preponderance of Steroids Therapy: A Case Report
Authors: Khan Qaisar Ali , Shahi Ameena , Shahi Alishba , Baqi Abdul , Tango Tamara , Verma Ravina , Hamid Asrah , Saravanan Priyadharshini , Alam Mazhar , Shinwari Ismail , Ain Hoor Ul
Published: October 2022

A 55-year-old female patient presented with generalized tonic-clonic
seizures. Laboratory evaluation showe low calcium (4.9 mg/dL), low PTH
(0.9 pg/mL), & positive activating CaSR antibodies. The condition was
diagnosed as autoimmune hypoparathyroidism. Vitamin supplements did not
correct the patient’s hypocalcemia and steroids were added to the
treatment.
Characterizing the orthodontic research literature: 2020
Authors: Chambers David W.
Published: October 2022

Objectives

To characterize features of the current orthodontic literature.

Methods and Materials

All research articles published in 2020 (N = 350) in the American Journal of Orthodontics and Dentofacial Orthopedics, The Angle Orthodontist, and the European Journal of Orthodontics were categorized on 48 features such as type of study (domain of generalization, subjects, and research design), analytical tools (statistical tests, power and normality of data, consistency of measurement, management of covariables, and corrections of multiple independent tests), and reporting characteristics. Consistency of the coding was high (κ > .990).

Results

The “most typical” article was a cohort study reporting multiple patient outcomes at a single treatment location. Soundness of analyses was uneven, with about half providing information on power or normality of the data and consistency of measurement. Few articles addressed covariables or adjusted for multiple tests of independent outcomes. Photos and flow charts were commonly used to explain methods, and results were presented in multiple formats. There was a clear association between design and reporting characteristics and type of study for systematic reviews, meta-analyses, and case reports. There were small but consistent differences across the three journals.

Conclusions

The quality of the orthodontic research literature has advanced at an uneven pace, and this review identifies areas that could be strengthened. Substantial gaps remain in achieving accepted standards for randomized controlled trials and opportunities exist for better understanding measures of effect through design and analysis using regression techniques to identify sources of variance.
Impact of Exercise Training at Different Intensity Levels on Cardiac Function and Exercise Capacity in Patients with Chronic Heart Failure: A Prospective Cohort Study
Authors: Zhang Zhenying , Wang Lizhong , Xi Jianing , Sun Xiaojing , Sun Xingguo
Published: October 2022

Objective: To investigate training at different intensity levels on cardiac function, exercise capacity, and health-related quality of life in patients with chronic heart failure.Methods: This prospective cohort study enrolled patients with chronic heart failure at Beijing Rehabilitation Hospital, Beijing, China from January 2018 to January 2020. Participants received conventional therapy (non-exercise group) or therapy plus cycle ergometer exercises at an intensity of 80% anaerobic threshold (EA group) and Δ50% power above anaerobic threshold (EB group) for 12 weeks. The primary outcome was peak oxygen uptake.Results: Forty-five patients (15/group) completed the study without serious complications. Exercise training at an intensity of Δ50% power above anaerobic threshold had better effects on exercise capacity than exercise at an intensity of 80% anaerobic threshold, as shown by a greater improvement in peak oxygen uptake (20.3 ± 4.1 vs 16.8 ± 3.2 mL/min/kg), peak O2 pulse (12.5 ± 2.3 vs 10.1 ± 2.1 mL/beat), and peak workload (123.1 ± 26.9 vs 102.8 ± 29.5 W) in patients with chronic heart failure (all p < 0.001). Exercise improved the 6-min walk test distance (control: 394.0 ± 74.1; EA: 481.4 ± 89.4; EB: 508.9 ± 92.5 m; p < 0.001) and health-related quality of life (control: 40.7 ± 12.3; EA: 16.2 ± 8.6; EB: 11.5 ± 6.4; p < 0.001).Conclusion: Compared with an intensity of 80% anaerobic threshold, exercise training at an intensity of Δ 50% power above anaerobic threshold was safe and had better effects on cardiac function, exercise capacity, and health-related quality of life.
LAY ABSTRACTThe aim of this study was to investigate training at different intensity levels on cardiac function, exercise capacity, and health-related quality of life in patients with chronic heart failure. Exercise training at an intensity of Δ 50% power above anaerobic threshold (mild anaerobic exercise) had better effects on exercise capacity than non-exercise and intensity of 80% anaerobic threshold (aerobic exercise). In addition, exercise resulted in improved health-related quality of life compared with non-exercise. Therefore, the benefit may be greater if the exercise intensity is increased appropriately under safe conditions.
Pelatihan Keterampilan Pengolahan Buah Cempedak untuk Jajanan Pasar Bagi Ibu PKK RT 03 Mugirejo
Authors: Winarti Hepy Tri , Mustangin Mustangin , Aulia Evitha Haltania , Alya Nur
Published: October 2022

Sebagian besar, ragam kebudayaan masyarakat Pulau Kalimantan mempunyai ikatan serta kedekatan yang begitu kuat dengan alam lingkungannya. Salah satunya bisa dilihat dari ragam kuliner jajanan pasar atau kuliner tardisional yang semuanya menunjukkan eratnya hubungan saling menguntungkan yang di bangun oleh masyarakat dengan alam lainnya. Olahan dari cempedak merupakan jajanan tradisional yang berasal dari indonesia terutama Kalimantan. Beberapa olahan makanan yang berbahan dasar buah cempedak yang menghasilkan cita rasa baru tanpa menghilangkan dari buah cempedaknya sendiri. Salah satu cara pengembangan dalam mengolah buah cempedak yang keberadaanya melimpah saat musim panen dan agar dapat meningkatkan pengetahuan maupun pendapatan masyarakat terutama bagi Ibu-Ibu PKK. Upaya mengolah cempedak ini agar memiliki varian jajanan pasar dengan kreasi yang berinovasi serta bernilai ekonomis untuk di jual. Melalui pelatihan pengolahan kue Jajan Pasar (Gabin Fla Cempedak dan Brownies Cempedak Kukus) kepada masyarakat yaitu memperkenalkan cara mengolah buah cempedak yang cenderung tidak diperhatikan saat musim panen kerena memiliki niai jual rendah akibat keberadaanya melimpah. Pelatihan tersebut ditujukan kepada Ibu-ibu PKK Rt 03 Mugirejo Samarinda. Pelatihan tersebut untuk mencoba mengkolaborasikan keunggulan yang dimiliki buah cempedak, khususnya pada pengolahan kue Jajan Pasar (Gabin Fla Cempedak) dengan kreasi yang lebih berinovasi.
Sosialisasi Aplikasi Akad-Akad Pembiayaan Syariah pada Sumber Daya Insani Bank Pembiayaan Rakyat (BPR) Syariah Se JABODETABEKTEN
Authors: A. Hubur  , Rizqullah Thohuri  , Jakaria  , Acep R Jayaprawira  , Muammar Kadafi  , Syakif Ahmad
Published: October 2022

Bank Pembiayaan Rakyat Syariah (BPRS) merupakah salah satu lembaga keuangan yang bertujuan untuk meningkatkan kesejahteraan ekonomi Islam terutama masyarakat ekonomi menengah kebawah dimana lokasinya biasanya ada di pinggiran kota dan pedesaan yang belum terjangkau secara maksimal oleh layanan bank Umum. Diantara permasalahan yang sering terjadi adalah sulitnya melakukan penyesuaian antara teori dan praktek dilapangan terkait akad-akad pembiayaan syariahnya, sehingga dipandang perlu peningkatan kualitas sumber daya insani agar akad-akad syariah terimplementasi dengan baik dan bukan hanya slogan semata. Tujuan dari kegiatan pengabdian kepada masyarakat (PKM) ini untuk meningkatkan pemahaman yang lebih mendalam dan aplikatif tentang akad-akad pembiayaan syariah pada sumber daya insani Bank Pembiayaan Rakyat (BPR) Syariah (KOMPARTEMEN BPRS ASBISINDO) se JABODETABEKTEN. Metode yang digunakan adalah ceramah dan diskusi melalui webinar dengan para peneliti sebagai narasumber dan perwakilan dari masing-masing BPRS yang berjumlah 150 orang menjadi pesertanya. Hasil dari kegiatan ini adalah sumber daya insani BPR Syariah memiliki pemahaman yang komprehensif dan integral serta mampu mengaplikasikan akad-akad syariah di tempat mereka bekerja yang sesuai dengan ketentuan perbankan dan maqhasid syariah.
Program Kemitraan Masyarakat pada Kelompok Pertenunan Arta Sedana, Sidemen, Kab. Karangasem
Authors: Mandasari IA Cynthia Saisaria
Published: October 2022

Kesenian di Provinsi Bali merupakan salah satu yang diminati oleh wisatawan khususnya kesenian dalam bidang kerajinan yaitu tenunan songket dan endek. Kekhasan itu tak hanya pada keunikan desain dan motif tradisionalnya yang kental nuansa seni budaya Bali, songket dan endek Bali juga tak kalah populer dibandingkan kain-kain nusantara lainnya. Hanya saja kenyataan dilapangan menunjukkan bahwa pemasaran endek dan songket khas Bali masih dilakukan secara manual sehingga di masa pandemic jumlah penjualan menurun drastis dan menyebabkan kerugian. Adapun tujuan dari penelitian ini yakni mengatasi masalah penurunan pemasaran, mengubah teknik pemasaran dan mengatasi perselisihan atar konsumen. Penelitian ini tergolong dalam jenis pengabdian kepada masyarakat dengan jumlah mitra sebanyak 50 orang yang tergabung dalam satu kelompok pengrajin. Metode pelaksanaan PKM ini dilakukan dengan bimbingan dan pendampingan untuk mengatasi permasalahan mitra, sehingga dapat meningkatkan penjualan dengan memperluas pangsa pasar melalui digital marketing. Hasil yang diperoleh dalam penelitian ini menunjukkan bahwa kegiatan pengabdian yang dilakukan dinyatakan berhasil dan dapat meningkatkan jumlah pemesan songket kelompok pengrajin. Selain itu kegiatan pelatihan ini juga dapat meningkatkan pengetahuan kelompok pengrajin mengenai cara pemasaran produk menggunakan teknologi digital.
Identification of Land Fire Risk Areas with Random Forest Using Landsat Image Data 8 OLI
Authors: Radandima Grandy Umbu Endalu Radandima
Published: October 2022

Land fire is a complex and serious problem affecting several human life sectors. Stimulating the occurrence of land fires caused by long dry seasons and erratic rainy seasons causes plants to dry up and die. Illegal land burning by irresponsible people for expansion and other interests. This study uses quantitative methods. The variables used are vegetation index values ​​obtained from Landsat 8 OLI images. The result of this research is that data classified using the random forest algorithm at RStudio produces a default number of 500 trees, and the number of variables tested in each split is 2. So, the estimated error rate of 2 out of the bag is 0.47%. Prediction and confusion matrix - train 403 data are less risky "0" (middle risk) of a fire, and there are 22 data of high risk of "1" (high risk) of a fire, with an accuracy value of 0.9914, 1. While the second prediction of the confusion matrix - test data, there are 167 data less risky "0" (middle risk) of fire. There is 1 data with a high risk of “1” (high risk) of a fire. There are seven high-risk data "1" (high risk) of fire, with an accuracy value of 0.9943, indicating a more accurate assessment of model accuracy, and the range is still good, around 96% to 99%. There are several incorrect classifications in the prediction and confusion matrix – train, which is slightly higher than the predictions of the two-confusion matrix – test, and sensitivity: 1.0000, which is the same in both prediction and confusion matrix – train & tes.
Pengaruh Pengawasan yang Dilakukan Pimpinan dan Lingkungan Kerja Fisik terhadap Efektivitas Kerja
Authors: Annisa Mutiara , Arita Sri
Published: October 2022

This study aims to determine and analyze: 1) the effect of supervision carried out by the leadership on the affectiveness of the employee’s work 2) the influence of the physical work environment on the effectiveness of the employee’s work 3) the influence of supervision carried out by the leadership and the physical work environment of employee work effectiveness. This type of research is descriptive associative. The total sample is determined by using the cluster proportional random sampling with a sample of 80 sample. The data analysis technique used is multiple linear regression analysis technique. Based on this research, it can be concluded that : 1) supervision carried out by the leadership has a significant effect on the work effectiveness of employees at the Departement of Youth and Sports Education in Kampar Regency 2) The Physical work environment has a significant effect on the work effectiveness of employees at the Departement of Youth and Sports Education in Kampar Regency 2) Supervision by the Leader and the physical Work Environment have a significant effect on the Work Effectiveness of Employees at the Departement of Youth and Sports Education in Kampar Regency. Keywords : supervision by leaders, physical work environment, work effectiveness
Integrating Telepsychiatry Based Care in Rural Acute Community Mental Health Services? A systematic literature review
Authors: Noble David , Haveland Siggy , Islam Md Shahidul
Published: October 2022

BACKGROUND: There is limited local literature specific to emergency department assessment and subsequent telepsychiatry follow up in the community and most literature on telepsychiatry does not cover the case of urgent assessment and crisis follow up in the community.
AIM: This literature review explores the use of videoconferencing technology to overcome the burden of distance and access to tertiary mental health services in regional and remote areas of Australia.
METHODS: A systematic search in Medline, CINAHL, Psychiatry Online, Google Scholar, and the NSW Health Clinical Info Access Program (CIAP) was conducted. A combination of key terms: “Telepsychiatry” OR “Mental Health Telemedicine” OR “Telemedicine” OR “Telehealth” OR “Videoconferencing” OR “Mental Health Videoconferencing” OR “Telepsychiatry Ethics” AND “Acute Community” AND “Emergency Assessment” were used. Based on the screening and eligibility criteria, 21 peer-reviewed articles published in English between 2005 and 2020 were included in the review.
RESULTS: Key themes were found which support the use of remote telepsychiatry. Common in the literature were themes of equivalence to in-person review, as well as themes of convenience, overcoming remoteness and timely access to specialist assessment. Ethical and technical considerations was also commonly cited. The literature search found no direct examples of an acute psychiatric assessment in the emergency department with a subsequent follow-up in the community using videoconferencing technology.
CONCLUSION: Telepsychiatry in both the home and emergency department areas had merit and equivalence to face to face review, with the added benefit of wider access and timeliness to specialist assessment and treatment.
Shield or Sword? Moral Distress in Aged Care Employees Related to Regulation and Compliance
Authors: Olley Richard
Published: October 2022

This paper reports on one finding of a qualitative study using interpretive phenomenological analysis (IPA) in a mixed-methods study examining the relationship between leadership style and job satisfaction in Australian aged care employees.  The qualitative data suggest that aged care employees are experiencing moral distress relating to the regulatory environment that governs the aged care sector and the compliance processes adopted by regulators and accreditors.
One of the reasons for the design and operationalisation of the regulatory environment is to protect vulnerable consumers, the public and the workforce.  However, the findings of this research are that it is this environment that also causes damage to the aged care workforce.  The question is whether compliance requirements and the regulatory scheme are a shield or sword. The causes of the moral distress were different for leaders and raters. This paper reports on this finding.  Moral distress is one of three undesirable outcomes identified in the study and labelled as Workplace Maladies.
Moral distress due to regulatory systems and processes experienced by leaders appears to be caused by different factors than the moral distress experienced by raters.  Leaders experienced moral distress because of the system and methods of regulatory and standards compliance. In contrast, their followership experienced other regulatory processes such as the scope of practice for health professionals and the requirement to supervise and accept responsibility for unregulated workers who do not have a scope of practice.  Unregulated workers reported that the absence of scope of practice is a cause of moral distress.
Recommendations are made for changes to the system and processes of compliance assessment and action and for developing a scope of practice for unregulated workers to reduce the moral distress experienced by aged care employees and thus reduce workforce turnover in an already scarce workforce.
Adaptation, Change and Leadership
Authors: Avery Mark
Published: October 2022

The second issue of the journal this year presents publications related to leading and managing within the health sector environment as well as a selection of papers based on presentations made at the recent International Conference on Embracing Change and Transformation.

In mobilising and enabling learning, growth and development in health organisations, the important linkages of adaptation, change to the leadership continuum provides both challenges and opportunities....
The role of intimate partner relationships on suicide risk among men in the construction industry in New Zealand
Authors: Ali Mohsin Rajabali Habib
Published: October 2022

My research is investigating suicide prevention among men within the NZ construction industry, with a focus on relationship breakdown which is a predominant theme preceding suicide by men in the industry. The proposed research will investigate the interface between family life and working in the construction industry and how these factors may potentially impact on mentalhealth and suicide risk.
ALİ VE NİNO ROMANINDA MİLLÎ MÜCADELE SAHNESİ OLARAK BAKÜ VE GENCE
Authors: Qasımlı Lale
Published: October 2022

Millî mücadele konusu, her milletin edebiyatında olduğu gibi Azerbaycan edebiyatında da hem nazım hem de nesir türündeki eserlerde çeşitli yönleriyle ele alınır. Azerbaycan edebiyatına ait romanlarda millî mücadele konusunun daha çok yan konu, fon olarak kullanıldığı görülür. Azerbaycan edebiyatının önemli romanlarından Ali ve Nino romanı, bu anlamda dikkat çeken bir eserdir. “Kurban Said” müstear ismiyle yazılan Ali ve Nino romanının yazarının gerçek kimliği tartışma konusudur. Orijinali Almanca olup birçok dile çevirisi yapılan romanın Azerbaycan
Türkçesine çevirisi 1990 yılında yapılmıştır. İlk bakışta bir aşk romanı olarak değerlendirilen Ali ve Nino; 19. yüzyılın başlarında dünyada, özellikle Kafkasya’da yaşanan tarihî olaylar,
Çarlık Rusyası’nın buradaki etkileri, bu etkiler sonucu yaşanan siyasi ve kültürel çatışmalar, Azerbaycan tarihi, Azerbaycan’ın bağımsızlık mücadelesi ve dönemin siyasi yapısı hakkında önemli bilgiler veren bir romandır. Konu, iki ayrı millete ve kültüre mensup iki gencin aşk öyküsü etrafında şekillenirken yan tema olarak millî mücadele meselesine değinildiği görülür. Ali ve Nino romanı, 30 bölüm hâlinde kurgulanmıştır. Romandaki olaylar Bakü’de başlar. Asıl mekân Bakü olmakla birlikte, başka ülke ve şehirler de görülür. Bakü’den sonra millî mücadelenin ikinci sahnesi olarak Gence şehri dikkat çeker. Bu çalışmada, Azerbaycan’ın iki büyük şehri olan Bakü ve Gence’nin millî mücadele tarihimizde tuttuğu yer ve bunun Ali ve Nino romanına nasıl yansıdığı üzerinde durulacaktır.
KIRGIZ TÜRKÇESİNDE ÇALGI ALETİ KULLANMAK ANLAMINA GELEN “ÇAL-, ÇERT-, OYNA-, TART-” FIILLERININ DİĞER TÜRK LEHÇELERİNDEKİ GÖRÜNÜMÜ
Authors: Çelik Fatih
Published: October 2022

Dillerde kullanılan fiiller, dilin esas yapısını oluşturur. Dil içerisindeki alıntı kelimelerin çoğunluğu isimlerdir. Fiiller ise dilin ana gövdesini oluşturan ve isimlere göre daha az alıntı yapılan unsurlardır. Türk lehçelerinin kelime hazinesi birbiriyle karşılaştırmalı olarak incelendiği zaman isimlerden oluşan kelimelerin daha çok farklılık gösterdiği görülmektedir. Her Türk topluluğu, yaşadığı çağ ve iletişim içerisine girdiği komşuların etkisiyle faklı dillerden kelimeler almıştır. Fakat lehçeler arasında zaman ve mekân ayrılığı ne kadar uzun bir dönemi kapsarsa kapsasın fiillerin küçük fonetik farklılıklar haricinde çoğunlukla ortaklığını koruduğu görülmektedir. Zaman, mekân vb. sebeplerden kaynaklanan farklılaşmanın daha çok kullanılan fiillerin karşıladıkları anlamlardaki değişmelerde olduğu tespit edilmiştir. Bu çalışmada Kırgız Türkçesinde “müzik aleti çalmak” anlamında kullanılan çal-, çert-, oyna-, tart- fiillerinin diğer Türk lehçelerindeki görünümü üzerinde durulmuştur. Müzik aleti çalmayı ifade eden çal-, çert-, oyna-, tart- fiillerinin Türk lehçelerinin bazılarında
ortak, diğerlerinde ise farklı anlamlara gelecek şekilde kullanıldığı görülmektedir. Çalışmada bu fiillerin Kırgız Türkçesi başta olmak üzere hangi lehçelerde ortak veya farklı kullanıldığı belirlenerek karşılıkları ve kullanım şekilleri ortaya konulmuştur. Aynı zamanda çal-, çert-, oyna-, tart- fiillerinin Eski Türkçeden günümüze kadar değişen yapısı üzerinde durulmuştur. Ele alınan fiillerde yeni anlamların hangi sebeplere bağlı olarak ortaya çıktığı veya çıkmadığı üzerine değerlendirmeler yapılmıştır. Çalışmanın sonuç kısmında hangi lehçede, hangi fiillerin “müzik aleti çalmak” anlamında kullanıldığına yer verilmiştir.
Pengaruh Sanksi Pajak dan Tax Amnesty Terhadap Keputusan Kepatuhan Wajib Pajak
Authors: Pratiknjo Meichelle Liman , Lasdi Lodovicus
Published: October 2022

Pajak merupakan salah satu sumber pendapatan negara dan ujung tombak APBN. Pemerintah berupaya untuk meningkatkan keputusan kepatuhan pajak dengan cara menerapkan kebijakan sanksi pajak dan tax amnesty. Penelitian ini merupakan penelitian eksperimen yang memiliki tujuan untuk mengetahui pengaruh sanksi pajak dan tax amnesty terhadap keputusan kepatuhan wajib pajak. Penelitian ini menggunakan desain eksperimen faktorial 2x2 yang dilakukan pada mahasiswa S1 Akuntansi Universitas Katolik Widya Mandala Surabaya yang telah menempuh dan lulus mata kuliah Perpajakan II dengan total 81 partisipan. Eksperimen dalam penelitian ini dilakukan dengan menyebarkan google form secara acak kepada partisipan. Pengujian pada penelitian ini menggunakan ANOVA. Hasil penelitian ini menunjukkan bahwa sanksi pajak dan  tax amnesty berpengaruh terhadap keputusan kepatuhan wajib pajak. Sanksi pajak yang tinggi cenderung meningkatkan keputusan kepatuhan wajib pajak dibandingkan sanksi pajak yang rendah. adanya tax amnesty cenderung meningkatkan keputusan kepatuhan wajib pajak dibandingkan tidak adanya tax amnesty.
Análise físico-química e da eficácia microbiológica de álcool em gel comercializados em farmácias de Mafra (Santa Catarina)
Authors: Rodrigues Samanta Komarchewski , Grossel Laís Aline , Fritsch Mário , Munhoz Antonio Carlos Mattar
Published: October 2022

O uso do álcool gel em procedimento de antissepsia das mãos e desinfecção de superfícies representa uma prática frequente nas instituições de saúde. Com a pandemia Covid-19, tornou-se hábito da população o uso do mesmo. O objetivo do trabalho foi analisar características físico-químicas bem como a eficácia microbiológica de diferentes marcas de álcool em gel comercializados em farmácias no período da pandemia de Covid-19. As análises físico-químicas compreenderam o teor alcoólico, cor, aspecto, valor de pH e resistência à centrifugação, e para a análise da eficácia microbiológica realizou-se um teste de desinfecção de bancada frente a bactérias Gram-negativas com cepa padrão de Salmonella typhimurium (ATT 14028). As amostras estudadas se encontram dentro dos padrões esperados para os aspectos físico-químicos bem como apresentaram eficiência na eliminação de bactérias em superfície contaminada.
Palavras-Chave: Álcool em gel. Eficácia microbiológica. Análise físico-química. Controle de qualidade.
Protection of the endangered fish lake minnow, Eupallasella percnurus (Pallas, 1814), within the Natura 2000 network in Poland: Present status and perspectives
Authors: Wolnicki Jacek , Sikorska Justyna , Radtke Grzegorz
Published: October 2022

The Natura 2000 network in Poland comprises over a thousand Special Protection Areas (SPAs) for birds and Special Areas of Conservation (SACs) for habitats and plant and animal species. One of these animals is the fish species lake minnow, Eupallasella percnurus, which is highly endangered with extinction and under strict protection. Presently it occurs in 27 SACs at 73 sites, i.e., considerably fewer than in the previous decade, when it occurred in 35 SACs at about 100 sites. Since it is very likely that the decline in the number of E. percnurus sites will continue in coming years, serious doubts are raised concerning the perspectives for its conservation within the Natura 2000 network and throughout Poland. The major threat to the existence of its habitats is climate change resulting in water bodies drying up at accelerated rates. Introductions of predatory fish species also contribute to the extinction of E. percnurus populations. Obviously, preserving the occurrence of E. percnurus in Polish inland waters will require the wide-ranging use of active conservation measures with a special emphasis on the revitalization of its most valuable habitats.
Electrical and Dielectric Properties of Discs Fabricated Using Periwinkle Shell Nanopowder and Dry Cassava Starch
Authors: Umanah Edidiong Iwok , Ekpenyong Nsikak Edet , Akpan Aniefiok Otu
Published: October 2022

Periwinkle shells and cassava effluent are wastes generated in very large quantities and majorly under-utilized. Due to existence of inefficient waste management systems in developing countries, their disposal is by indiscriminate dumping, a practice that adversely affects the environment and human health. Hence, there is an urgent need to examine their potentials for possible engineering applications in order to further proffer a safe way of managing them. In this work, Periwinkle shell nanopowder and cassava starch were prepared from the wastes and then used to fabricate disc-shaped samples. The samples were developed with various lengths/thicknesses and in triplicates, after which their electrical and dielectric properties were evaluated. For lengths/thicknesses of 2.6 mm to 6.5 mm, the mean electrical resistance and electrical resistivity obtained were (9.89 to 23.00) × 106 Ω and (8.231 × 105) Ωm respectively. Over the temperature range of 20°C to 50°C, the respective results for thermal sensitivity, activation energy, and temperature coefficient of resistance assessment were (6982 ± 158) K, 0.60 eV, and −8.12 %/K. More so, it was observed that quality factor increased with sample’s thickness and frequency of applied signal. With increase in frequency from 0.10 kHz to 100.00 kHz, the dielectric constant of the studied sample decayed exponentially from (20.54 ± 0.04) to (1.67 ± 0.01). Aside meeting the market requirements for NTC thermistors, it was found that the sample could serve as a suitable alternative to conventional dielectrics like mica, paper, plastic film, tantalum oxide, and aluminium oxide for production of capacitors.
Case Study of the Evidence of PM1& PM2.5 Contribution on PM10 from Podul De Piatra– Iasi City
Authors: Chiruţă Ciprian , Tănasă Ioana Mădălina , RoȘu Iulian Alin , Tudose Ovidiu Gelu , SluȘer BrânduȘa , Cazacu Marius Mihai
Published: October 2022

The importance of air quality monitoring has been strongly demonstrated in numerous scientific studies. This study, carried out in an intense circular intersection, brings additional arguments that the monitoring of the fine particles like PM1 and PM2.5 that influence in more than 80% the concentration of PM10 particles must be measured at several points. Few were the cases [approx. 20%] in which the increase of PM10 concentrations is given by particles with diameters from 2.5 to 10 μm, most likely caused by the re-suspension of dust particles. Grimm Aerosol Technik Germany and SC INOESY SRL conducted a campaign for monitoring the air quality [PM1, PM2.5, PM10] in Iasi, Stone Bridge area, from 8 to 22 February 2018. The monitoring point was located close (150 m) to the APMIS-01 station of the National Environmental Protection Agency.
Certain Considerations on the Atomicity of Set Functions
Authors: Gavriluţ Gabriel
Published: October 2022

In this paper, certain considerations concerning the atomicity of non-additive set functions are given. Several properties and examples are provided.
ERN1 dependent impact of glutamine and glucose deprivations on the pyruvate dehydrogenase genes expression in glioma cells
Authors: Shatokhina Hanna O. , Khita Olena O. , Minchenko Dmytro O. , Tsymbal Dariia O. , Luzina Olha R. , Danilovskyi Serhiy V. , Sliusar Myroslava Y. , Levadna Liudmyla O. , Minchenko Oleksandr H.
Published: October 2022

Objective. The aim of the present study was to investigate the expression of pyruvate dehydrogenase genes such as PDHA1, PDHB, DLAT, DLD, and PDHX in U87 glioma cells in response to glutamine and glucose deprivations in control glioma cells and endoplasmic reticulum to nucleus signaling 1 (ERN1) knockdown cells, the major endoplasmic reticulum (ER) stress signaling pathway, to find out whether there exists a possible dependence of these important regulatory genes expression on both glutamine and glucose supply as well as ERN1 signaling.

Methods. The expression level of PDHA1, PDHB, DLAT, DLD, and PDHX genes was studied by real-time quantitative polymerase chain reaction in control U87 glioma cells (transfected by empty vector) and cells with inhibition of ERN1(transfected by dnERN1) after cells exposure to glucose and glutamine deprivations.

Results. The data showed that the expression level of PDHA1, PDHB, DLAT, and DLD genes was down-regulated (more profound in PDHB gene) in control glioma cells treated with glutamine deprivation. At the same time, ERN1 knockdown modified the impact of glutamine deprivation on the expression level of all these genes in glioma cells: suppressed the sensitivity of PDHB and DLD genes expression and removed the impact of glutamine deprivation on the expression of PDHA1 and DLAT genes. Glucose deprivation did not significantly change the expression level of all studied genes in control glioma cells, but ERN1 knockdown is suppressed the impact of glucose deprivation on PDHX and DLD genes expression and significantly enhanced the expression of PDHA1 and PDHB genes. No significant changes were observed in the sensitivity of PDHX gene expression to glutamine deprivation neither in control nor ERN1 knock-down glioma cells. The knock-down of ERN1 removed the sensitivity of DLAT gene expression to glucose deprivation.

Conclusion. The results of this investigation demonstrate that the exposure of control U87 glioma cells under glutamine deprivation significantly affected the expression of PDHA1, PDHB, DLAT, and DLD genes in a gene specific manner and that impact of glutamine deprivation was modified by inhibition of the ER stress signaling mediated by ERN1. At the same time, glucose deprivation affected the expression of PDHA1, PDHB, PDHX, and DLD genes in ERN1 knockdown glioma cells only. Thus, the expression of pyruvate dehydrogenase genes under glutamine and glucose deprivation conditions appears to be controlled by the ER stress signaling through ERN1.
Prolactinoma - which patients react favorably to cabergoline medication?
Authors: Karatas Savas , Hacioglu Yalcin , Rakicioglu Taskin
Published: October 2022

Objective. Prolactinoma, as a common endocrine disorder and the most frequent type of pituitary tumor, acts primarily as a suppressor on the gonadal functions. It is generally successfully treated with dopamine agonists; however, treatment resistance still remains in an unneglectable ratio. In this study, we aimed to identify factors, which may play a role in the treatment response.

Methods. Seventy-six patients with prolactinoma, who have been routinely followed between 2018 and 2022 in Istanbul Research and Educational Hospital Endocrinology Outpatient Clinic, were included into the study. Initial prolactin level, adenoma size, baseline weight, body mass index (BMI), glucose, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, and triglyceride levels were obtained from the patient’s medical records. The patients were divided into two groups: treatment respondent and non-respondent (refractory) ones, according to treatment response in the duration as suggested by the guidelines. The treatment respondent and non-respondent groups were compared according to the initial and the 3rd month prolactin levels, adenoma size, weight, BMI, and metabolic values.

Results. The initial tumor diameter was 15.27±10.62 mm in the refractory and 7.42±4.42 mm in the treatment respondent groups (p=0.01). The refractory group had higher prolactin baseline level 269.96±275.78 µg/l vs. 124.55±67.35 µg/l of the respondent group (p=0.01). The refractory group had higher the 3rd month prolactin level 50.97±52.55 µg/l vs. 29.70±27.31 µg/l of the respondent group (p=0.04). The refractory group had higher frequency of cystic/hemorrhagic adenoma (47.6%, n=11/21) (p=0.01), baseline pituitary failure (33.3%, n=7/21) (p=0.01), and baseline cavernous sinus invasion (25.8, n=5/21) (p=0.01). The treatment respondent group had lower initial body weight (69.54±17.51 kg vs. 83.29±16.21 kg) (p<0.01), and lower BMI (25.98±5.47 kg/m2 vs. 27.69±6.42 kg/m2) (p=0.02).

Conclusions. In this study, initial tumor size, male gender, weight, BMI, the 3rd month prolactin level, initial pituitary deficiency, and cystic/hemorrhagic component in pituitary imaging in patients with prolactinoma were associated with a lower treatment response.
Pricing Strategies in the Revenue Management System of Hotel Enterprises
Authors: Melnyk Iryna , Barna Marta
Published: October 2022

Subject and purpose of work: Substantiation of the principles of formation of the pricing policy of hotel enterprises while considering the segmentation of the client base, existing patterns and pricing strategies according to revenue management system.

Materials and methods: the material of the article is based on the study of theoretical and practical aspects of the pricing strategy in the system of management of hotel enterprises. Scientific articles and practical recommendations of revenue managers were used, on the basis of which the principles of pricing hotel services were summarized, depending on the preferences and requirements of various consumer segments.

Results: It has been established that when using certain strategies, it is necessary to systematize how and when hotel services are booked by representatives of the main market segments, as well as to correctly assess the elasticity of their demand.

Conclusions: Revenue management from the sale of hotel services involves the use of flexible prices for the same type of revenue, the value of prices are determined depending on the period of sale of this product until the product becomes unusable. This premise implies the need to develop an appropriate tariff policy and define certain volumes of these services.
Comparison of the Return on Investment of Two Energy Production Companies in Hungary Using Different Biomass-Based Technologies
Authors: Deak Zsuzsanna
Published: October 2022

Subject and purpose of work: Using renewable organic material for energy generation exhibits an increasing trend globally, also in Hungary. The aim of the Renewable Energy Action Plan of the European Union is to increase the share of energy production from renewable resources to 32% by 2030. At present, renewable energy sources represent 10.2% of Hungary’s primary energy consumption.

Materials and methods: This study has examined the financial feasibility of two companies in Kunság region in Hungary that participate in the renewable energy production market with different types of technologies, that of a biogas facility and a short rotation energy forest plantation. As financial incentives for the establishment and propagation of bioenergy producing enterprises are offered both in the EU and Hungary, calculations are presented both with and without subsidies.

Results: The results show that regardless of the production method, without subsidies, none of the businesses could make a profit in the period under review.

Conclusions: The main reasons behind unprofitable operations are the initial high capital outlay, high logistics costs, immature technological solutions and suppressed purchasing prices.
A Device Free Lunch Break program: An experiment to promote a balanced used of electronic devices in Middle Secondary International schools.
Authors: Andreadis Ioannis , Watts Martin
Published: October 2022

Since the introduction of a Bring Your Own iPad scheme in the Middle Years section of a large International School, concerns have been raised from school community members regarding students’ overuse of their devices, especially during lunch breaks. Hence, the device free lunch break (DFLB) programme was introduced with the aim of reinforcing existing guidance for students about achieving and maintaining a balanced approach to their use of devices. The DFLB programme was planned based on market research strategies and included all the school community members including students, parents/guardians and staff. The findings from statistical analysis of the data showed significant similarities between staff and parents/guardians’ perceptions of student device use in terms of the student overuse of electronic devices. However, analysis showed that the opinions of parent/guardians and staff contrasted those expressed by students. The data also showed evidence that the introduction of the DFLB programme resulted in increased student recognition of the importance of making face-to-face social contacts with their classmates during their lunch break.
Phenotypic Carbapenemase Production and bla
OXA detecting by PCR in Acinetobacter baumannii isolates from a Hospital of Infectious Diseases from North-East Romania
Authors: Buzilă Elena-Roxana , Dorneanu Olivia Simona , Luncă Cătălina , Jelihovschi Igor , Iancu Luminiţa Smaranda
Published: October 2022

Introduction: In the last 40 years, Acinetobacter baumannii has been among the bacteria known to acquire multiple mechanisms of antibiotic resistance and, as a result, it is now one of the pathogens involved in healthcare-associated infections with multidrug resistant strains. Our study aimed to assess the production of carbapenemases in carbapenem-resistant A. baumannii by means of phenotypic methods and polymerase chain reaction technique (PCR), as well as to appraise the performances of carbapenemase detection by phenotypic tests compared to the PCR approach.

Materials and Methods: We used phenotypic methods (E-test MBL, CIM, MHT, Rosco® Kit/OXA/MBL, OXA-23 K-SeT® assay) to investigate the production of carbapenemases in 43 carbapenem-resistant A. baumannii isolates, and PCR to screen for the genes blaOXA-23, blaOXA-24, blaOXA-58, blaOXA-51, blaVIM, blaIMP and blaNDM.

Results: The carbapenem inactivation method (CIM) at 2 hours, CIM at 4h, OXA-23 K-SeT® assay, Rosco® Kit/OXA, and modified Hodge test (MHT) identified 26%, 63%, 65%, 81%, and 42% carbapenemase-producing isolates, respectively. The phenotypic E-test MBL detected metallo-β-lactamase (MBL) production in 79% of strains. PCR revealed blaOXA-51 in all the isolates, blaOXA-23 in 35/43 (81%), blaOXA-24 in 28/43 (65%), blaVIM in 7/43 (3%) and blaOXA-58, blaIMP, blaNDM were not detected.

Conclusion: Because phenotypic tests do not highlight all the carbapenemase-producing strains, their results must be interpreted with caution relative to their level of performance, and negative results should be confirmed by means of PCR.
Autoantibodies Against ROS-Human Serum Albumin-A Potent Immunological marker in Depressed Individuals with Smoking History
Authors: Sherwani Subuhi , Khan Mohd W. A.
Published: October 2022

Background: Depression is one of the significant problems in adults that accounts for up to five percent of cases worldwide.

Methods: Volunteers were divided into eight groups, and their serum samples were tested for FBG, carbonyl contents, IFN-γ and TNF-α. Reactive oxygen species (ROS) modified human serum albumin (HSA) (ROSHSA) was used as an antigen and levels of serum autoantibodies were estimated by direct binding and inhibition ELISA in all subjects.

Results: Significant biophysical structural modifications were observed in ROS-HSA with increased carbonyl contents compared to native-HSA (N-HSA). Significantly high levels of carbonyl content (2.68 ± 0.33 nmol/mg protein; p > 0.001) and pro-inflammatory cytokines IFN-γ (7.4 ± 0.61 pg/ml; p > 0.001) and TNF-α (1.47 ± 0.23 pg/ml; p > 0.001) were detected in serum samples from F-D-S. Similarly, a high level of autoantibodies against ROS-HSA was observed in females who were depressed and smokers (F-D-S) group (0.89 ± 0.07; p > 0.001) compared to males who were both depressed and smokers (M-D-S) (0.66 ± 0.049). Furthermore, inhibition ELISA results exhibited high recognition of serum autoantibodies from F-D-S subjects (78.6 ± 5.7 mean maximum percentage inhibition MMPI) compared to M-D-S (58.8 ± 5.2 MMPI) subjects.

Conclusion: Incoherence, long term unchecked chronic psychological stress may cause oxidation of blood proteins, which subsequently result in structural alterations of biomolecules, thus generating new-epitopes, capable of inducing autoantibodies specific for ROS-modified proteins. These autoantibodies may be a potential marker for subjects suffering from depression to understand the state of immune imbalance.