bluuebunny/crossref_metadata_2025 huggingface dataset:
Histopathological spectrum of salivary gland lesions in Ajmer region, Rajasthan, India
Authors: Pachori Geeta , Chandra Subhash , Bihari Naseem A. , Kasliwal Neena
Published: June 2019

Background: There is a wide spectrum of salivary gland lesions with morphological and clinical diversity which makes it a difficult task for histopathological interpretation. Tumours of salivary glands are uncommon accounting for 3-10% of the total tumors of head and neck region and less than one percent of all tumours. The aim of this study was to recognize various histomorphological patterns of salivary gland lesions, their frequency, age, gender and site wise distribution.Methods: This study was carried out from June 2015 to May 2018 in the department of Pathology, JLN Medical College and associated Group of Hospitals, Ajmer. Total 121 cases of salivary gland lesions were included. Specimens were processed and stained by Hematoxylin and Eosin stain followed by histopathological examination.Results: Out of total 121 cases, 43.8% were non-neoplastic and 56.2% were neoplastic. In non-neoplastic lesions predominant was chronic sialadenitis (50.9%) followed by mucocele (28.3%) which commonly seen in submandibular gland (47.17%). Among neoplastic cases, 79.4% were benign and 20.6% were malignant lesions. Neoplastic lesions commonly were seen in parotid (75%). Pleomorphic adenoma was the commonest benign tumour (81.4%). Mucoepidermoid carcinoma was the most common malignant salivary tumour. Benign tumours were common in third and fourth decades, whereas malignant tumours were more common in fifth and sixth decades. Male predominance was seen in overall salivary gland lesions.Conclusions: Histopathological examination is mandatory in the diagnosis of salivary gland lesions because of their wide spectrum of histomorphology.
Correlation of risk factors with Glasgow coma scale to predict the severity and outcome of children with non-traumatic coma
Authors: Reddy A. Manikanteswara , Sreedhar G. , Belavadi Gangadhar B.
Published: June 2019

Background: Non-traumatic coma is the problem of pediatric group, accounts 10-15% in hospital admissions. Assessment of the severity of coma is useful to speculate the survival. The aim was to assess outcome in pediatric non-traumatic coma with role of Glasgow coma scale and modified Glasgow coma scale.Methods: Total of 80 cases of non-traumatic coma between 1 month to 12 years, coma severity was assessed by using Glasgow coma scale. A score of less than 8 and more than 8 were used for analysis of outcome.Results: The maximum number of patents with non-traumatic coma were in the age group of 1 month-5 years, 40 children (50%). On neurological examination 42 (52.5%) children has GCS score of >8, 38 cases (47.5%) has GCS <8, 20 children had meningeal signs, 7 children had cranial nerve deficit (7th nerve), 9 children had decebrate posture. Out of 80 cases, 8 cases expired (10%), 4 cases were discharged against medical advice (4%), 68 cases were improved and discharged (85%), among these, 8 cases were discharged with complication (11.7%). Overall mortality was (10%) (8/80), males outnumbered females in frequency with ratio of 1.28:1. CNS infection accounted for almost about 66%.Conclusions: Children with GCS and MGCS scores of less than 8 have poor prognosis and a very high probability of death. Those with GCS score of more than 8 have good prognosis. Identification of these cases at the outset can help prepare the treating physician to plan critical care referral and to give a preliminary assessment of outcome to the family.
Changes in the physiological parameters of newborns in the first one hour of life
Authors: Y. Shasidhar Reddy , Syed Abdul Mohid , Belavadi Gangadhar B.
Published: June 2019

Background: The transition from a fetus to a newborn is the most complex adaptation that occurs in human experience. This study assessed three physiological parameters viz. temperature (core and peripheral), oxygen saturation and heart rate so as to avoid the delay in normal transitional adaptation.Methods: This cross-sectional observational study was done at Narayana Medical College Hospital, Nellore, Andhra Pradesh, India. A total of 150 neonates born from June 2017 to February 2018 were monitored for heart rate, oxygen saturation, core and peripheral temperature from birth to 60 minutes.Results: Most of the mother’s (45.33%) were aged between 22 to 25 years and the mean age was 23.75±3.64 years. History of consanguineous marriage was noted in 33.33%. The mode of delivery was vaginal in 70.67% of the babies. The mean gestational age was 38.74±1.36 weeks. The birth weight among 62% of the babies was between 2.5 to 3.49 Kgs and mean birth weight was 2.81±0.49 kgs. The meconium stained liquor and requirement of resuscitation was noted in 9.33% and 10.67% respectively.Conclusions: Significant difference was noted with regard to heart rate in babies with active resuscitation, low birth weight (<2.5 kg), meconium stained liquor and warmer care compared to normal babies. There was variation in oxygen saturation in babies who required resuscitation and warmer care, and those who had low birth weight. The mean peripheral and core temperature were different in babies with abdominal care compared to warmer care.
Analysis of complete blood counts in rotaviral gastroenteritis with special emphasis on platelet indices
Authors: Maralihalli Mahesh B. , Deshpande Kavan R. , Deshpande Pallavi K
Published: June 2019

Background: The objectives of this study was to analyze complete blood counts in rotaviral gastroenteritis with special emphasis on platelet indices.Methods: Children diagnosed as rotavirus gastroenteritis and healthy controls were enrolled in this study. Severity of acute gastroenteritis was classified into mild, moderate and severe grades using Vesikari score. Rotavirus was determined in fresh stool samples using rapid diagnostic rotavirus antigen test. Hemoglobin, leukocyte, neutrophil to lymphocyte percentage ratio, platelet counts, mean platelet volume (MPV), platelet distribution width (PDW) and platelet crit (PCT) levels were assessed for all children. It’s a case control study conducted at Pediatric Speciality Hospital.Results: There were 30 cases with mean age 1.58 years. Healthy controls were 30 with mean age 2.10 years. Mean Hb was lower in cases. Mean of platelet counts was higher in cases. Mean MPV levels was lower in cases. Mean PCT value was higher in cases. Mean MPV to platelet ratio value was lower in cases. All parameters values showed no significant difference among mild, moderate and severe groups of rotaviral gastroenteritis cases. Platelet count was negatively correlated with Hb, MPVP and positively correlated with TLC and PCT. MPV was positively correlated with MPVP and PDW. PCT was negatively correlated with Hb, MPVP and positively correlated with TLC and platelet count.Conclusions: MPV can be used as negative acute phase reactant in rotavirus gastroenteritis and so is the MPV to platelet ratio. Platelet count is acute phase reactant in rotavirus gastroenteritis and so is the platelet crit value.
Risk factors for necrotizing enterocolitis in neonates:a prospective study
Authors: Sahoo Manas Ranjan , Nagasree Pydi , Swetha Lanka , Vasundhara Arigela
Published: June 2019

Background: Necrotizing enterocolitis (NEC) is mostly limited to preterm babies due to immaturity of gut. NEC is one of important cause of neonatal mortality and morbidity in the neonatal intensive care units all over the world.Aim of study is to find the antenatal and post-natal risk factors associated with necrotizing enterocolitis in neonates admitted to NICU.Methods: A prospective study was conducted on 45 neonates with necrotizing enterocolitis fulfilling the predetermined inclusion criteria. A detailed antenatal history including all maternal risk factors, birth history including the need for resuscitation and type of resuscitation was recorded. The gestational assessment was done by the New Ballard Score.Results: Pregnancy induced hypertension accounts as a risk factor to most of the cases of NEC 18 (40%), followed by setting for sepsis 12 (26.6%), least being gestational diabetes mellitus 1 (2.2%).Conclusions: Prematurity is found to be the most common risk factor followed by patent ductus arteriosus and sepsis. Most common antenatal risk factor was PIH (Pregnancy induced hypertension).
A study to assess the practices of mothers of under-five children in childhood diarrhoea in a tertiary care hospital of Northeast India
Authors: Majumder Nilratan , Dhar Dipak Kumar
Published: June 2019

Background: Diarrhoea is one of the major causes of morbidity and mortality in under-five children. The incidence of diarrhoea has remained almost unchanged over the past few decades. A mother is the primary care-giver of a child. Therefore, one of the key factors that determine the survival of a sick-child is her attitude and practices in the event of diarrhoea. The present study was therefore undertaken to understand the different aspects of their care-giving behaviour.Methods: A hospital-based cross-sectional study was carried out in the Department of Paediatrics, Agartala Government Medical College and G. B. Pant Hospital, Agartala, Tripura, India over a period of two months. 700 mothers of under-five children attending the OPD were interviewed with a pre-designed and structured interview schedule.Results: The usage of ORS was about one-fourth. And only one-fifth out of all the participating mothers could show how to prepare ORS solution correctly. Correct practices regarding various aspects of administering ORS solution like duration of usage, frequency of administering, duration of the therapy, etc were not observed in majority of the participating mothers. A preference for home-made fluids was also noted in most of the participants. Educational level and past experience of managing a child with diarrhoea significantly affected their practices.Conclusions: Even though ORS is widely and easily available, easy to use and cost-effective, considerable work needs to be done in the context of adequate practices in its administration to a child affected by diarrhoea and increase its acceptability.
Prediction of neonatal hyperbilirubinemia by cord blood analysis to diagnose subsequent hyperbilirubinemia
Authors: Rafi S. K. Mahammad , Gandikota Vani , Belavadi Gangadhar B.
Published: June 2019

Background: the study was aimed to determine the predictive value of cord bilirubin and 24th hour serum bilirubin levels in identifying newborn babies at risk of developing significant hyperbilirubinemia.Methods: A total 300 term neonates with a mean birth weight of 2.58±0.23 kg ranging from 1.92 kg-4.1kg were included in this study. Under strict aseptic precautions cord blood sample were collected from all newborns for analysis of serum bilirubin levels, and haemoglobin levels.Results: The incidence of significant hyperbilirubinemia in this study was 14%. Among jaundiced newborns sex ratio M/F:1.6:1(male female ratio 1.1:1). Mean Cord bilirubin levels in babies who subsequently developed hyperbilirubinemia was 2.798±0.5559 mg/dl and in others were 1.511±0.3260 mg/dl and the difference was statistically significant. There was a statistically significant correlation between cord bilirubin and neonatal jaundice. Cord bilirubin ≥2 mg/dl had good predictive value in identifying newborns who are likely to develop significant hyperbilirubinemia later.Conclusions: Babies with cord blood bilirubin ≥2 mg/dl can be followed up in the hospital for 5 days, the time of peak neonatal hyperbilirubinemia to prevent the babies discharged early and later readmission for neonatal hyperbilirubinemia.
Diagnostic utility of fine needle aspiration cytology in pediatric age group in a tertiary care centre
Authors: Bhagat Ritu , Jandial Roopali
Published: June 2019

Background: Fine Needle Aspiration Cytology (FNAC) is a simple, cost effective, minimal invasive and a rapid diagnostic technique. The present study was designed to study the role of fine needle aspiration cytology and its utility in paediatric lesions. It also specifies the spectra of different lesions in the paediatric age group.Methods: The present study was performed in the Department of Pathology, in a tertiary care centre of Jammu, Jammu and Kashmir, India. All pediatric patients aged 0-17 years with palpable or deep-seated lesions were included in the study over a period extending from January 2017 to December 2018. The aim was to study the utility of FNAC in paediatric age group.Results: A total of 200 cases of FNAC in pediatric age group were studied. Out of total 200 cases maximum number of patients i.e. 59% were between 11-17 years. Male to female ratio was 1.7:1. A preponderance of lymph nodes over other sites i.e. 129/200 (64.5%) was noted.Conclusions: FNAC is a safe, rapid, accurate and cost-effective procedure with good patient acceptance with no essential morbidity and can be used as an initial screening tool in superficial and deep-seated lesions in pediatric age group.
Clinical study of meningitis in children and role of adenosine deaminase in differentiating tubercular from non-tubercular meningitis
Authors: Pandey Deepmala , Yadav Ankur
Published: June 2019

Background: In diseases where cell mediated immunity plays an important role like in tuberculosis, CSF (Cerebrospinal fluid) adenosine deaminase (ADA) activity is increased. Hence, this testing is done especially among children with suspected tubercular meningitis. The objective of this was to study role of Adenosine Deaminase in differentiating tubercular from non-tubercular meningitis.Methods: This was a hospital based cross sectional study was carried out among 50 children of proven meningitis for a period of two years. CSF ADA levels were done for all cases. They were divided into tubercular meningitis and non-tubercular meningitis group and compared.Results: Incidence of tuberculous meningitis (TBM) was found high in the age group 5-8 years. Male:female ratio was 2.3:1. Fever was present in all cases followed by vomiting and neck rigidity. CSF AFB was positive in 3 cases (6%). Neuroimaging was done in all cases in which 3 patients had basal exudate in which 2 patients had TBM and 1 patient was Non-TBM. 3 patients had hydrocephalus in MRI in which 2 had TBM diagnosed and 1 had non-TBM. As per ADA levels, 10 were diagnosed as TBM out of which 8 patients had ADA level ≥10 IU/L and 2 had ADA level <10 IU/L which was missed by ADA and later confirmed by other modalities.Conclusions: It was concluded that if ADA level in CSF is ≥10IU/l the diagnosis of TBM should be considered.
Iron deficiency and febrile seizures: a retrospective analysis
Authors: Gajare Bharat , Engade Madhuri , Khatri Anuj , Sharma Pooja
Published: June 2019

Background: Febrile seizures (FS) are the commonest cause of seizures in children, with 2-5% of neurologically healthy children experiencing at least 1 episode. Iron deficiency is reported to be one of the most prevalent nutritional problems in the world today, especially in developing countries, with an estimated 46%-66% people affected. Our study is an attempt to clarify the relation between iron deficiency and first febrile seizure.Methods: The present study was a case control study carried from December 2016 till June 2018 in a tertiary care hospital at Aurangabad, Maharashtra, India. The study was done after obtaining approval from Institutional ethical Committee.Results: 77 cases and equal number of controls were included. Males were most commonly affected (>50%) as compared to females in both groups. Highest number of cases and controls were in the age group 0.5 to 1 year group, followed by 1-2 and 2-3 years group. Upper respiratory tract infection was most common etiological factor. Anemia (Hb<11 gm/dl) was seen in in 84% of the cases and 65% of the controls. Serum iron and total iron binding capacity (TIBC) was reduced in cases as compared to controls and this difference was highly statistically significant.Conclusions: Iron deficiency is a modifiable risk factor for first episode of febrile seizures in Indian children of age group 6 months to 5 years its early detection and timely correction may be an important determinant for prevention of febrile seizure in children.
Effect of education and socio-economic status on parenting among pre-school and school going children
Authors: Barua Devendra , Saxena Shruti
Published: June 2019

Background: Parenting is the process of promoting and supporting the physical, emotional, social and intellectual development of a child from infancy to adulthood. Parenting is a complex activity that includes much specific behavior that works individually or together to influence child’s outcomes.Methods: It is prospective observational study carried out in the Department of Pediatrics, Shyam Shah Medical College and associated Gandhi Memorial Hospital, Rewa, Madhya Pradesh, India during the period from July 2008 to June 2010. Parents were interviewed with predesigned proforma. Parenting was graded in to three grades (1, 2 and 3) according to the performance of parents in various aspects of parenting.Results: In this study, 60 parents had 155 children constituting 2.5 children per family and male to female ratio was 1.18:1. We observed that literate parents performed well in all aspects of parenting (i.e. behavioral, physical, emotional, mental, spiritual, nutritional), but illiterate parents could not score on these points especially in spiritual and nutritional aspects. 33% graduate parents fulfilled the criteria for grade 3 parenting in nutritional aspects, 55% intermediate passed parents in nutritional aspects were in grade 3, whereas there were more than 50% parents in behavioral, physical and emotional aspects who had education level up to primary class.Conclusions: Educational status of parents has a positive impact on almost all aspects of parenting and the educational status of mothers appeared to be even more influential. Socioeconomic status of parents and residential area have a great influence on all aspects of parenting.
Acute kidney injury in a critically ill influenza: a H1N1 infected child
Authors: Jayapalan Dinesh Kumar , Geminiganesan Sangeetha , Parthasarathy Shruthi , Varadharaju Niranjana , Bhaskar Nithya
Published: June 2019

Influenza H1N1 infection is a globally recognized epidemic and is known for several extra-pulmonary complications. Here, for the first time we report a case of a six-year old male child with severe H1N1 infection with acute kidney injury. The child was referred to our center with fever, chills, cough and cold for 2 days. Investigations revealed H1N1 infection with deranged LFT and RFT with anuria. Child was subjected to mechanical ventilation and received higher antibiotics in addition to oseltamivir. The child underwent 13 cycles of hemodialysis and renal profile normalized after a period of 35 days. Our case highlights the importance of recognizing extra-pulmonary complications of H1N1 infection in the pediatric population and the preparation required by healthcare practitioners to reduce the associated mortality.
Study of determinants of contraceptive practices and impact assessment of counselling on acceptance of contraception in tribal area of Rajasthan, India
Authors: Mathur Medha , Parmar Piyush , Mathur Navgeet
Published: June 2019

Background: Unmet need of family planning affects the society by uncontrolled population explosion. Tribal population being socioeconomic deprived group requires special attention for contraceptive needs. This study was planned to study the determinants of contraceptive practices and impact of intervention in the form of counselling over the family planning acceptance behaviour.Methods: This community based longitudinal study was conducted for duration of six months in selected areas of Udaipur district, by two stage sampling method. Baseline data was collected followed by counselling of non-users of contraception and later on collection of post intervention data for comparison.Results: Out of total 422 study subjects, 193 (45.7%) were contraceptive users and 229 (54.3%) were non-users. All the participants had knowledge about permanent method (100%) of sterilization followed by barrier methods (62%). Non-users of contraception were counselled and their practices improved significantly (p<0.001) afterwards.Conclusions: The knowledge of family planning methods is present inadequately among tribal and non-tribal eligible couples and actual practice of contraceptive use is lacking which requires efforts of health workers thorough counselling to change their attitude towards adoption of family planning practices.
Impact of hand washing intervention program on knowledge, attitude and practices about hand hygiene among school children in urban area of Kolhapur city
Authors: Potdar Pallavi A. , More T. A. , Wagh Anjali , Desai Manjiri M. , . Raja
Published: June 2019

Background: Good hand hygiene is an important infection control measure as person-to-person contact via hands is a common mode of transmission for gastrointestinal and respiratory infections. There are promising results of proper hand washing for reducing many kinds of diseases. For improvement of knowledge and practice of hand washing, health education intervention is very much fruitful. The objectives of the study were to study knowledge, attitude and practice regarding hand washing among primary school children; to study impact of hand washing intervention program on knowledge, attitude and practices about hand hygiene.Methods: The study was conducted from 1st March 2018 to 30th December 2018 in the government aided primary schools of urban area in Kolhapur. Initially baseline school health check-up was done to study knowledge, attitude and the actual hand washing practices both in school as well as at home among children. Extensive health education programs were conducted to demonstrate correct hand washing technique and importance of hand washing was taught; with involvement of teachers from schools. Data was collected using interview questionnaires. Hand washing facility and availability of water and soap in school was also noted. Teachers were actively involved to motivate students for hand washing with soap before eating and after visiting toilet facility. Follow up visits were done to study parameters like improvement in knowledge, attitude and practices about hand hygiene.Results: After our health education sessions there was significant improvement in knowledge, attitude and practices regarding hand washing among the school children.Conclusions: From our study findings it can be stated that after our health education sessions there was significant improvement in hand washing behaviour among the participants. We tried to sensitize teachers also so that they will motivate children in future.
Menstrual hygiene: knowledge and practices during menstruation among adolescent girls in urban slums of Jorhat district, Assam, India
Authors: Das Netri , Tasa Anadi Swami
Published: June 2019

Background: Menstruation is still clouded by taboos and socio-cultural restrictions resulting in adolescent girls remaining ignorant of the facts of menstruation and hygienic practices, which sometimes results in adverse health outcomes. The present study was carried out to assess the knowledge and practices regarding menstrual hygiene, to find out the disorders during menstruation and to determine the factors associated with existing practices of menstrual hygiene among adolescent girlsMethods: A community-based cross-sectional study was conducted in two randomly selected urban slums of Jorhat district from March to August 2017 among 110 adolescent girls using predesigned pretested proforma. Data were analyzed using SPSS; association was determined using chi-square test with Yates correction or Fisher’s exact test, as appropriate.Results: 47.27% girls were aware about menstruation prior to menarche. Mother was the first informant in 65.38% of them. 69.09% were ignorant about the source of menstrual bleeding. Sanitary pads were used by 59.09% of girls. Majority (97.27%) practiced some form of restriction during menstruation. Dysmenorrhoea was the most common complaint (53.63%). Type of absorbent used was significantly associated with literacy status of girls and their mothers, socio-economic status, religion and prior knowledge about menstruation. Educational status of girls and their mothers were also significantly associated with satisfactory cleaning of external genitalia during menstruation.Conclusions: Ignorance and unsafe practices regarding menstruation, menstruation related problems and traditional beliefs and restrictions are quite common among adolescent girls in urban slums. Literacy status and awareness are the most important factors affecting the menstrual behaviours.
Clinical perculiarities of preauricular sinus abscess: a tertiary health centre experience
Authors: Aliyu Daniel J. , Mohammed Abdullahi
Published: June 2019

Background: Preauricular sinus abscess is a sequellae of an infected squamous epithelial lined preauricular sinus tract, commonly seen in pediatric population. This study aim to determine the clinical profile of preauricular sinus abscess in Sokoto, Nigeria.

Methods: This was a retrospective study carried out between June 2011 to May 2014 of all patients with preauricular sinus abscess that presented to the department of ear, nose and throat. Data extracted from clinical records were bio-data, duration of symptoms, and history of recurrence and associated congenital anomalies, sides of involvements, sensitivity results, treatments options and outcome. Data obtained were analyzed using simple statistical tables.  

Results: Seventeen patients were seen during the study period with preauricular abscess (PA). There were 5    (29.4%) males and 12 (70.6%) females with a ratio M:F of 1:2.4. The age range was from 5-34 years. Prevalence of PA is high in the 1-10 years age group. Six patients (35.3%) had ruptured abscess. Unilateral PA involving the left side in 12 (70.6%) patients was most common. Two patients had previous incision and drainage prior to presentation. Staphylococcus aureus was the most common isolated organism. Twelve patients (70.6%) were lost to follow up after surgical drainage and 5 (29.4%) patients had wide local excision of the sinus tract to remove all vestiges of squamous epithelium as opposed to simple sinectomy. One patient had recurrence.

Conclusions: We emphasize the need for proper health education of definitive surgery after surgical drainage of preauricular sinus abscess.
Endoscopic removal of foreign bodies from the upper aerodigestive tract: a retrospective study from a tertiary care hospital
Authors: Vellamparambil Sreeja Raj , Menon Arjun Gopinath , Rajagopalan Vinayakumar Ariyamparambil
Published: June 2019

Background: Foreign bodies (FB) in the upper aero-digestive tract pose major challenges to the otorhinolaryngologist in both diagnosis and management. Aspirated and ingested foreign bodies are often emergencies, leading to inadequate study, poor preparation and improper attempts at removal. A retrospective analysis was done on cases which were managed for the upper aero-digestive tract FBs in a tertiary care hospital in South India and the result is presented in this article.

Methods: Retrospective study was done on 100 patients diagnosed as cases of foreign body in upper aerodigestive tract on the basis of detailed history, clinical examination and radiological investigation. They underwent per oral endoscopy under general anaesthesia for retrieval of foreign body.  

Results: Age group more prone for foreign body ingestion or aspiration was <10 years and >50 years. Most common site of impaction in oesophagus is cricopharynx and in airway is right bronchus. Most common type of FB is chicken bone. Most common symptom in FB ingestion is FB sensation and in case of FB aspiration it is cough. Most (82%) of the FBs were radio opaque.

Conclusions: Accurate history and clinical examination were the keystones in diagnosis and prevention of complications of FB lodgement in aerodigestive tract. Negative history and or normal imaging do not rule out a foreign body.
A clinical study of cisplatin induced ototoxicity in head and neck malignancies
Authors: Dwivedi Gunjan , Kumar Manoj , Gupta Vikas , Sood Amit , Patnaik Uma
Published: June 2019

Background: Head and neck malignancies are the sixth most common cancers worldwide, a vast majority of these cases is squamous cell carcinomas. Cisplatin is one of the main modalities of treatment. However it leads to dose dependent ototoxicity. The aim was to determine the cisplatin induced ototoxicity in head and neck squamous cell carcinomas. The objectives are: (1) to determine the severity and type of hearing loss; (2) to determine the effects on the vestibular system; (3) to correlate the cause effect relationship to dosage and duration of treatment; and (4) to devise a protocol for early detection and prevention of ototoxicity.

Methods: The study was conducted over 50 randomly selected head and neck cancer patients at malignat diseases treatment centre (MDTC) of a tertiary care centre in Eastern India at Command Hospital (EC), Kolkata between October 2008 and October 2010.  

Results: 22% of the patients developed cochlear ototoxicity. No patient had any vestibulotoxic effects.

Conclusions: Cisplatin manifests with dose dependent ototoxicity. Pre as well as post treatment audiometric monitoring may help to provide early evidence of decreased hearing ability, leading to the possible limitation of the severity of ototoxicity.

 
Recurrent nodular fasciitis of the external auditory canal: an intriguing diagnosis
Authors: Anto Ronald , Sampathkumar Raghunandhan , Kameswaran Mohan
Published: June 2019

The external auditory canal can sometimes present with unique pathology since it is a vibrant environment possessing a variety of anaomical structures including bone, cartilage, skin, ceruminous glands and fibro-collagen tissues. Nodular fasciitis is an intriguing entity which rarely presents in the external ear canal as a growth. The diagnosis is made only through histopathological confirmation after ruling out similar benign or malignant lesions including ceruminoma, granuloma or carcinoma. Fasciitis being of fibrous origin has propensity to recur wherein management becomes more challenging. This is a clinical profile of a case of recurrent nodular fasciitis which was surgically managed and followed up with no further recurrence.
O tamanho corporal de crianças e adolescentes: limites ao direito de escolha
Authors: Costa Rafael de Oliveira , Costa Leandro de Oliveira , Martines Piroutek Aline
Published: June 2019

A questão da obesidade e seu tratamento vem assumindo especial interesse das comunidades jurídica e científica. O presente trabalho propõe, inicialmente, a existência de um “direito a ter qualquer tamanho corporal” como manifestação do direito ao livre desenvolvimento da personalidade. Contudo, diante da ausência de caráter absoluto, passa-se a investigar, também, a existência de limites a esse direito. Sustenta-se, assim, que ao verificar situações de obesidade mórbida que efetivamente impeçam crianças ou adolescentes de terem uma vida digna, com acúmulo anormal de gordura corporal, torna-se possível a intervenção do Ministério Público e do Poder Judiciário, por meio de demandas de internação compulsória e destituição do poder familiar, relativizando-se o “direito a ter qualquer tamanho corporal”.
Sensibilização ambiental de alunos da educação básica do município de Varre-Sai/RJ a partir da avaliação da qualidade da água do Ribeirão Varre-Sai
Authors: Nunes Carolina Ramos de Oliveira , Miller Daniella Honorato Mesquita , Araújo Thiago Moreira de Rezende , Oliveira Vicente de Paulo Dos Santos de
Published: June 2019

O Ribeirão Varre-Sai é um importante manancial hídrico para o município de Varre-Sai no estado do Rio de Janeiro. O presente trabalho avaliou a qualidade da água do Ribeirão por meio de parâmetros físico-químicos e microbiológicos, realizou a identificação da percepção ambiental de alunos do município em relação ao Ribeirão Varre-Sai e, por fim, realizou a sensibilização ambiental dos estudantes. As análises físico-químicas e microbiológicas realizadas permitiram constatar que o Ribeirão vem sendo degradado, principalmente pelo lançamento de esgoto doméstico. A identificação da percepção ambiental dos alunos, por meio da utilização de questionário e proposta de desenho, possibilitou o desenvolvimento da atividade de sensibilização ambiental elencando os problemas enfrentados pelo Ribeirão Varre-Sai e propondo ações mitigadoras, por meio de palestra expositiva, conversa informal e confecção de cartazes.
Estudo de Tratamentos Aplicados a Lixiviado de Aterros Sanitários
Authors: Limaverde Filho Aricelso Maia , Silva Luiz André
Published: June 2019

Nos dias atuais, muito se discute sobre o grande volume de resíduos sólidos gerados nas grandes cidades e qual a melhor forma de acondicioná-los e de tratar seus subprodutos. Os aterros sanitários são conhecidos por receber grande quantidade e variedade de resíduos sólidos urbanos. Decorrente disto, o chorume (lixiviado) produzido na decomposição desses resíduos possui características peculiares e grande complexidade química, sendo conhecidos também por sua elevada turbidez, cor e odor característicos, além da alta recalcitrância de seus constituintes. Este trabalho teve como objetivo apresentar algumas técnicas utilizadas no tratamento de lixiviados de aterros e avaliar seu desempenho através da aplicação de algumas dessas técnicas. O chorume utilizado foi coletado no aterro de Gericinó (Bangu - Rio de Janeiro). Os tipos de tratamento que serão abordados neste trabalho envolvem processos de coagulação/floculação, adsorção em carvão ativado e filtração por membranas. Foram realizados inicialmente - como etapa de pré-tratamento - os testes em batelada de coagulação, seguidos do processo de adsorção em carvão. Também se verificou o comportamento das amostras filtradas após o pré-tratamento. Ao final dos ensaios, obteve-se um clarificado com demanda química de oxigênio (DQO) até 90% menor, remoção de 97% da absorbância e ausência quase total de turbidez.
Participação da geração eólica e fotovoltaica na matriz enérgica brasileira – 2013 a 2017
Authors: Brito Fabiano Baldez da Costa , Siqueira Jairo Lúcio Gomes , Turra Mariana Bacelar , Moreira Marcos Antonio Cruz , Villela Flavia Ribeiro
Published: June 2019

A diversificação de fontes de energia, notadamente daquelas classificadas como renováveis, é uma tendência mundial, sendo o Objetivo de Desenvolvimento Sustentável da ONU nº 7, na chamada Agenda 2030 (ONU, 2015). O Brasil tem neste quesito grande destaque no cenário mundial, pois nos últimos anos tem utilizado em média mais de 40% do seu consumo oriundo de fontes renováveis de energia elétrica, muito superior à média mundial e dos países da OCDE (EPE, 2018). Atualmente, as energias eólica e fotovoltaica têm se destacado com forte crescimento em participação na matriz energética brasileira. Considerando que o subsídio para as energias renováveis é rateado entre todos os consumidores, entender os reflexos dos subsídios no desenvolvimento da utilização dessas fontes de energia é necessário para a avaliação dos resultados obtidos. Estudar as fontes eólica e fotovoltaica, que vêm se destacando no cenário mundial, é importante para a compreensão desse fenômeno. O objetivo do presente trabalho foi analisar a evolução da participação das fontes de energia eólica e fotovoltaica (EFV) na matriz energética brasileira de geração de energia elétrica no período de 2013 a 2017. Os dados utilizados foram extraídos da Agência Nacional de Energia Elétrica e tratados utilizando as aplicações computacionais Microsoft® Excel® 365 e R ver. 3.5.1. Para isso, foram utilizados métodos de Estatística Descritiva tanto gráficos quanto de resumos numéricos, assim como métodos de normalização e de correlação de Pearson. Constatou-se que o aumento da participação dessas fontes de energia na matriz energética brasileira é consistente, mesmo com as limitações climáticas ocorridas em determinadas partes do ano, indicando que os subsídios governamentais têm surtido efeito.
Área de Preservação Permanente (APP) de Corpos Hídricos em Perímetro Urbano: Conflito no Uso e Ocupação das Terras no Município de Rio das Ostras/RJ
Authors: Oliveira Bárbara Barcellos de Almeida Lopes , Ferreira da Silva José Augusto , Oliveira Vicente de Paulo Santos de
Published: June 2019

As Áreas de Preservação Permanente (APPs) são alvos constantes de pressões antrópicas. Sendo assim, a sua delimitação e a sua caracterização compõem uma importante informação para a tomada de decisão no que se refere a medidas que visam proteger ou recuperar essas áreas ambientalmente sensíveis. O objetivo deste estudo foi avaliar as APPs de corpos hídricos e quais são os tipos de conflitos no uso e na ocupação do solo urbano dessas áreas no município de Rio das Ostras, bem como as resoluções que têm sido efetuadas pelos órgãos de fiscalização ambiental, considerando a efetividade das intervenções. A pesquisa está baseada em método exploratório-descritivo com revisão da literatura na área ambiental, com foco nas APPs de corpos hídricos. Neste sentido, buscou-se um universo de estudo com as publicações mais relevantes, a partir do modelo do estudo bibliométrico. É possível concluir que as APPs são essenciais para a manutenção da função ecológica do ambiente, mas que, em conflito com o uso e a ocupação do solo, acabam sendo ineficazes na proteção do meio.
Uso de Adsorventes como Alternativa no Tratamento de Contaminantes Orgânicos em Águas e Efluentes Líquidos
Authors: Santos Letícia de Jesus Castro Morais dos , Azevedo Gleide Nascimento
Published: June 2019

Atualmente toneladas de microcontaminantes orgânicos são lançados nos corpos hídricos através dos esgotos sanitários, industriais e hospitalares, os quais possuem uma elevada carga química que, quando não tratada corretamente, causa mudanças irreparáveis ao meio. Desse modo, o presente artigo apresenta um estudo bibliográfico de variadas metodologias de adsorventes usados na adsorção de contaminantes orgânicos.
Akuntabilitas Pengelolaan Dana BOS Di SDN Pringgowirawan 02 Kecamatan Sumberbaru Kabupaten Jember Tahun 2014
Authors: Julantika Tutus , Supatmoko Djoko , Kurrohman Taufik
Published: June 2019

his research aims to know the application of accountability system within the management of Accountability Of School Operational Assistance (BOS) fund and how the responsibility of Accountability Of School Operational Assistance (BOS) fund is used foward Pringgowirawan 02 Elementary school Sumberbaru in 2014 method of collecting data in the research is done through interview with the school principal and the chamberlain of Accountability Of School Operational Assistance (BOS). Besides, the researcher also uses direct observation foward the school area. The goal of this research is the management of Accountability Of School Operational Assistance (BOS) fund which is gained from the total planned and the total used of Accountability of School Operational Assistance (BOS) fund itself. The compatibility of Accountability of School Operational Assistance (BOS) fund used can be seen from the ratio shown. Ratio in this research is the number which is demonstrated the ability of school to use Accountability of School Operational Assistance (BOS) fund based on the planned Accountability of School Operational Assistance (BOS) fund in the earlier semester.
Analisis Pengaruh GCG dan Kinerja Keuangan Terhadap Pengungkapan Islamic Social Reporting (ISR)
Authors: Hasanah Nindya Tyas , Widiyanti Novi Wulandari , Sudarno S.
Published: June 2019

This study aims to analyze of good corporate governance and financial performance influences to disclosure Islamic Social Reporting (ISR). Islamic Social Reporting (ISR) is a social responsibility disclosure index accordance to the sharia principles. Populations in this study are all companies that listed in Jakarta Islamic Index exchange in 2011-2015. The sampling method in this tudy is puposive sampling. The total number of samples in this study were 55 research samples. The disclosure of ISR is obtained by content analysis through scoring method from corporate annual reports. The analytical techniques was conducted by descriptif statistic and classical assumption test and also hypothesis was tested using multiple liniear regression method, Adjusted R2 test, F test and t test. The analysis showed that audit committee size, liquidity and profitability significantly affect the disclosure of ISR. Meanwhile, commissioners board size and leverage does not affect the disclosure of ISR. Keywords: Islamic Social Reporting (ISR), good corporate governance, financial performance, Jakarta Islamic Index
Pengaruh Partisipasi Anggaran Terhadap Kinerja Manajerial dengan Komitmen Organisasi dan Motivasi Sebagai Variabel Intervening
Authors: Giusti Guillerma , Kustono Alwan Sri , Effendi Rochman
Published: June 2019

This study aims to show the causal relationship of participation with commitment and motivation for mangerial performance. Partial Least Square (PLS) is used with purposive sampling to explain causal relationships and linkages between several variables. The research is sourced from the permanent employees of Micro, Small and Medium Entreprise Service Office of Jember Regency as many as 45 permanent employees. The results of this study indicate that budget participation has a positive effect on managerial performance, organizational commitment and motivation. Furthermore, organizational commitment and motivation have a positive effect on managerial performance, and the result of final test of motivation have positive effect to organizational commitment.Keywords: Managerial Performance, Organizational Commitment, Motivation, Budget Participation Abstract
As diversas faces da internacionalização
Authors: Trevisol Marcio Giusti , Fávero Altair Alberto
Published: June 2019

O artigo reflete a internacionalização da educação superior como uma das grandes preocupações das universidades e de certas políticas de organismos internacionais (OCDE, Banco Mundial, Unesco) e agências nacionais (Capes, CNPq). Para além de pressupor a interculturalidade, a integração das pesquisas e dos conhecimentos, a solidariedade entre os povos, também se caracteriza como sendo um espaço de debates e embates entre atores do próprio campo e na intercessão dos campos sociais envolvidos. Nestes campos de disputa surgem discursos que revelam as diversas faces da internacionalização. O objetivo é analisar o sentido de internacionalização contido nos documentos de duas universidades comunitárias do Sul do Brasil.  A pesquisa caracteriza-se como bibliográfica, documental, de corte analítico e comparada. O universo da pesquisa é duas universidades comunitárias do Sul do Brasil que são analisadas e comparadas a partir dos seus documentos, sobretudo, do Plano de Desenvolvimento Institucional (PDI) e do Plano Institucional de Internacionalização. Em ambas as Universidades, fica evidenciado o entendimento que a internacionalização é o caminho para a consolidação da pesquisa, do ensino e da extensão com vistas a competividade e ao produtivismo global. Porém, em ambas as políticas institucionais de internacionalização são recentes e obedecem a normatividades legais não estando claro os objetivos e interesses da internacionalização para o fortalecimento da missão dessas universidades. Ainda importante destacar, que apenas uma universidade já conta com o Plano Institucional de Internacionalização.
Cytotoxicity test and characteristics of demineralized dentin matrix scaffolds in adipose-derived mesenchymal stem cells of rats
Authors: Sari Desi Sandra , Maduratna Ernie , Ferdiansyah F. , Sudiana I Ketut , Rantam Fedik Abdul
Published: June 2019

Background: Demineralized dentin matrix (DDM) scaffold is a substitute material for the bone contained in human teeth. DDM is a scaffold-derived tooth dentine containing type I collagen and bone morphogenetic protein (BMP). While DDM possesses the ability to perform osteoinductive and osteoconductive roles, a cytotoxicity test of DDM scaffold remains extremely important in evaluating the level of toxicity of a material if cultured in cells. Adipose-derived mesenchymal stem cells (ADMSCs) are multipotent in nature because they contain progenitor cells and have the potential for differentiation via adipogenic, osteogenic and chondrogenic pathways. ADMSCs are also known to have high biocompatibility and the ability to combine with other bone material. Purpose: The purpose of this study was to determine the cytotoxicity and characteristics of DDM scaffolds derived from bovine teeth in the ADMSCs of rats cultured in vitro. Methods: This research constituted an experimental study. ADMSCs were isolated from the inguinal fat of rats. Thereafter, DDM was extracted from bovine teeth and formed 355-710 μm-sized particles. DDM scaffolds were assessed using SEM and the effects of DDM scaffolds on the cell viability of ADMSCs at concentrations of 10%, 50%, and 100% analyzed by means of 3-4,5’dimethylihiazol-2-yl,2.5-di-phenyl-tetrazolium bromide (MTT) assay. The results obtained were then analyzed by an ANOVA to establish the difference between the groups. Results: SEM results showed the diameter sizes of the dental tubulis DDM scaffolds to be approximately 4.429 μm and 7.519 μm. The highest cell viability (97.08%) was found by means of an MTT test to be in ADMSCs at a concentration of 10% compared to those at concentrations of 50% and 100%. Conclusion: In conclusion, DDM scaffold derived from bovine teeth with a particle size of 355-710 μm produces a low cytotoxicity effect on ADMSCs.
The effects of Acanthus ilicifolius chloroform extract on TLR-2 expression of macrophages in oral candidiasis
Authors: Andriani Dwi , Pargaputri Agni Febrina
Published: June 2019

Background: Immunosuppressed conditions due to long-term corticosteroid and tetracycline consumption are susceptible to fungal invasion, especially by Candida albicans (C. albicans), that requires treatment of oral candidiasis. Toll like receptor-2 (TLR-2) plays a role in candida recognition. Nystatin is regularly employed for oral candidiasis, but produces certain side-effects. Chloroform extract of Acanthus ilicifolius (A. ilicifolius) leaves represents both a potent inhibitor of C. albicans growth and an antioxidant. Purpose: This study aimed to compare the effect of A. ilicifolius leaf chloroform extract and nystatin treatment on TLR-2 expression in oral candidiasis immunosupressed models. Methods: This study constitutes a true experimental investigation incorporating a post test-only control group design. 20 healthy male Rattus novergicus (Wistar), aged 12 weeks and with an average weight of 250g, were immunosuppressed through oral administration of dexamethasoneand tetracycline for a period of 21 days before being induced with C. albicans (ATCC-10231) 6 x 108 for two weeks. The subjects were divided into five groups (n=4/group): healthy (H), no-treatment(P), nystatin treatment(N), A. Ilicifollius (8%) treatment (AI-1) and A. ilicifollius (16%) treatment (AI-2). The subjects were treated for 14 days, with their tongue being subsequently biopsied. TLR-2 expression was subjected to immunohistochemical examination, observed under a microscope (400x magnification) and statistically analyzed (one-way Anova, LSD-test, p<0.05). Results: TLR-2 expression of P (6.25 ± 2.5), N (11.25 ± 0.96), AI-1 (13.00 ± 1.15), AI-2 (12.75 ± 1.7) was higher than H (1.75 ± 0.5). Significant differences existed between N to P, N, AI-1, AI-2; P to N, AI-1 and AI-2 (p<0.05). No significant differences were present between N, AI-1 and AI-2 (p < 0.05). Conclusion: A. ilicifolius extract can increase expression of TLR-2 in oral Candidiasis-immunosuppressed models. A. ilicifolius extract produces the same effect in increasing TLR-2 expression when compared to nystatin.