bluuebunny/crossref_metadata_2025 huggingface dataset:
Cytomegalovirus infection may be oncoprotective against neoplasms of B-lymphocyte lineage: single-institution experience and survey of global evidence
Authors: Janković Marko , Knežević Aleksandra , Todorović Milena , Đunić Irena , Mihaljević Biljana , Soldatović Ivan , Protić Jelena , Miković Nevenka , Stoiljković Vera , Jovanović Tanja
Published: March 2022

Background
Although cytomegalovirus (CMV) is not considered tumorigenic, there is evidence for its oncomodulatory effects and association with hematological neoplasms. Conversely, a number of experimental and clinical studies suggest its putative anti-tumour effect. We investigated the potential connection between chronic CMV infection in patients with B-lymphocyte (B-cell) malignancies in a retrospective single-center study and extracted relevant data on CMV prevalences and the incidences of B-cell cancers the world over.
Methods
In the clinical single-center study, prevalence of chronic CMV infection was compared between patients with B-cell leukemia/lymphoma and the healthy controls. Also, global data on CMV seroprevalences and the corresponding country-specific incidences of B- lineage neoplasms worldwide were investigated for potential correlations.
Results
Significantly higher CMV seropositivity was observed in control subjects than in patients with B-cell malignancies (p = 0.035). Moreover, an unexpected seroepidemiological evidence of highly significant inverse relationship between country-specific CMV prevalence and the annual incidence of B-cell neoplasms was noted across the populations worldwide (ρ= -0.625, p < 0.001).
Conclusions
We try to draw attention to an unreported interplay between CMV infection and B-cell lymphomagenesis in adults. A large-scale survey across > 70 countries disclosed a link between CMV and B-cell neoplasms. Our evidence hints at an antagonistic effect of chronic CMV infection against B-lymphoproliferation.
The Level of Sustainability Reporting of Malaysian IPO Companies
Authors: Abbas Yasir Abdullah , Mehmood Waqas , Manhal Mohammed H. , Aman-Ullah Attia
Published: March 2022

Purpose –
This paper aims to determine the level of sustainability reporting (SR) in Malaysian initial public offering (IPO) companies. Due to the general poor awareness about SR and its dimensions, these aspects have not been receiving the necessary push from the public domain.
Design/methodology/approach –
This study is exploratory in nature employing secondary data through the content analysis of the annual reports of 139 sampled IPOs listed on Bursa Malaysia for the period of 2007–2017. The data was analysed using descriptive statistics, whilst extent and quality were used as measures of SR.
Findings –
The results show that the extent and quality of SR in Malaysian IPO companies have improved over the years with a small improvement from one year to the next. The extent of SR was at 20.70% with society disclosure at 32.77% and energy disclosure at 22.48%, while employee disclosure showed the highest prevalence at 34.87% and product disclosure recorded the lowest prevalence at 9.88%. The quality of SR was at 32.04% with society disclosure recording the highest prevalence at 36.09%, energy disclosure at 20.28%, employee disclosure at 34.13%, and finally product disclosure indicating the lowest prevalence at 9.50%.
Research limitations/implications –
The dimensions of SR namely society, energy, employee, and product issues received little interest from most of the companies. This study proposes the need for additional studies investigating SR in IPO companies.
Originality/value –
This study makes a significant contribution to the information related to SR in Malaysian IPO companies. The findings can facilitate financial institutions and regulatory agencies in driving responsibility on the part of companies regarding SR issues.
A multifaceted strategy to improve recombinant expression and structure determination of complex proteins: A Trypanosoma surface protein as an example
Authors: Sülzen Hagen , Votrubova Jitka , Dhillon Arun , Zoll Sebastian
Published: March 2022

Identification of a protein minimal fragment amenable to crystallisation can be time- and labour intensive especially if large amounts are required and the protein has a complex fold and functionally important post-translational modifications. In addition, a lack of homologues and structural information can further complicate the design of a minimal expression construct. Recombinant expression in E. coli promises high yields, low costs and fast turnover times, but falls short for many extracellular, eukaryotic proteins. Eukaryotic expression systems provide an alternative but are costly, slow and require special handling and equipment. Using a member of a structurally uncharacterized, eukaryotic receptor family as an example we employ hydrogen-deuterium exchange mass spectrometry (HDX-MS) guided construct design in conjunction with truncation scanning and targeted expression host switching to identify a minimal expression construct that can be produced with high yields and low costs.
Wood quality of Astronium fraxinifolium and Enterolobium gummiferum for charcoal production
Authors: Santos Vaniele Bento dos , Baraúna Edy Eime Pereira , Colen Fernando , Baldin Talita , Monteiro Thiago Campos , Arantes Marina Donária Chaves
Published: March 2022

This paper aimed to evaluate the quality of wood and charcoal of Astronium fraxinifolium and Enterolobium gummiferum from Brazilian savannas (Cerrado). Discs from three trees of each species were removed at a height of 1.30 m above ground level. The samples were prepared for the analysis of the energy density and chemical components of the wood and for the production of charcoal at two final carbonization temperatures (350 and 450 ºC). After characterizing the charcoal, the carbonization yield and charcoal productivity per unit of wood volume were calculated. The wood of native species had potential for energy purposes. E. gummiferum charcoal stood out for its low ash content, and A. fraxinifolium wood presented higher apparent density and, consequently, higher carbonization yield and charcoal productivity per unit of wood volume. Charcoals produced at the two final carbonization temperatures presented adequate parameters for the steel industry and domestic use. The final temperature of 350 ºC is indicated as it presents higher gravimetric yield and energy yield of carbonization.
Efficacy and safety of different neoadjuvant radiation doses in patients with local advanced rectal cancer：A retrospective study
Authors: Xu Yuyan , Zou Haizhou , Shao Zhenyong , Zhang Xuebang , Ren XiaoLin , He Huijuan , Zhang Dahai , Du Dexi , Zou Changlin
Published: March 2022

Background: The research aimed to evaluate the efficacy and safety of different radiation doses (45Gy and 50.4Gy) on neoadjuvant in patients with LARC.Methods: Patients with LARC between January 2016 and June 2021 were retrospectively enrolled in the study, all of them underwent neoadjuvant chemoradiotherapy and radical surgical. XELOX regimen was administered for two cycles before nCRT. 72 patients received radiation dose with 50.4Gy while 45 patients with 45Gy. During radiotherapy, concurrent chemotherapy was employed as capecitabine alone. Surgery was performed within 5-12 weeks after nCRT.Results: Baseline characteristics in both groups were not statistically significant. The rate of well pathological regression in the 50.4Gy group was 59.72% (43/72) while in the 45Gy group was 64.58% (31/48) (P>0.05). The rate of radiographic remission in the 50.4Gy group was 70.83% (51/72), compared with 68.75% (33/48) in the 45Gy group(P>0.05). Significant differences existed in the incidence of several adverse events (radioactive proctitis, myelosuppression and intestinal obstruction or perforation) between the 50.4Gy group and the 45Gy group(P<0.05).Conclusions: Higher radiation dose could increase the incidence of several adverse events, meanwhile, it failed to improve the rate of pathological regression and imaging remission.
Roseomonas rosulenta sp. nov., isolated from rice paddy soil
Authors: Lee Hyo-Jin , Whang Kyung-Sook
Published: March 2022

Three bacterial isolates, Gram-stain-negative, non-motile, coccobacilli-shaped bacteria, strains OP-27T, OP-5 and OP-30, were isolated from rice paddy soil. Phylogenetic analyses based on 16S rRNA gene sequences revealed that three isolates belonged to the genus Roseomonas, showing the highest sequence similarities to Roseomonas sediminicola FW-3T (98.1%), Roseomonas lacus TH-G33T (98.0%), Roseomonas soli 5N26 T (97.8%), Roseomonas eburnea BUT-5T (97.5%), Roseomonas alkaliterrae YIM 78007T (97.4%), Roseomonas oryzicola YC6724T (97.4%), Roseomonas rubea MO17T (97.4%) and Roseomonas terrae DS-48T (97.1%) and less than 94.3% similarities to other species of the genus Roseomonas. The genome size of strain OP-27T was 5.2 Mb in a single contig with DNA G+C content of 71.2%. The genome included 5164 predicted protein-coding genes, as well as 48 tRNA, 4 rRNA and 4 mRNA genes. The average nucleotide identity value between strain OP-27T and type strains of related species of the genus Roseomonas were 81.1-83.1%, and the digital DNA–DNA hybridization values of strain OP-27T and the related strains were 24.6~26.8%, respectively. The DNA–DNA hybridization values between strains OP-27T, OP-5 and OP-30 were 84-100% and its closest relative, Roseomonas sediminicola KACC 16616T was 21.1%. The major fatty acids were C18:1 ω7c, C18:1 2-OH and C16:0 and predominant quinone was Q-10. Based on its distinctive phenotypic, phylogenetic, and chemotaxonomic characteristics, the three strains are considered to represent novel species of the genus Roseomonas, for which the name for which the name Roseomonas rosulenta sp. nov. is proposed. The type strain is OP-27T (=KACC 21501T=NBRC 114497T).
Abemaciclib plus fulvestrant for the treatment of hormone receptor-positive/human epidermal growth factor receptor 2-negative breast cancer with cystic brain metastases: a case report and literature review
Authors: chu zhaohui
Published: March 2022

Cystic brain metastases in patients with breast cancer are rare. They have a worse prognosis than solid brain metastases, and they are less sensitive to radiotherapy. We report a case of hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2−) metastatic breast cancer with cystic brain metastases. The patient underwent treatment with docetaxel combined with capecitabine for 5 months, followed by anastrozole maintenance therapy for 10 months and palbociclib combined with exemestane for 22 months. Cystic brain metastases emerged and bone metastases increased in number. A missense mutation in PIK3CA (exon 10, c.1633G > A [p.Glu545Lys]) was detected by whole-exome next-generation sequencing of peripheral blood samples. After whole-brain radiotherapy (40 Gy/20 fx) combined with 3 months of treatment with everolimus and fulvestrant, cystic brain metastases demonstrated partial regression (PR), but extracranial bone metastases continued to increase in number. Thus, the patient underwent fourth-line treatment with abemaciclib (100 mg bid) combined with fulvestrant (500 mg). Three months later, cystic brain metastases significantly demonstrated PR and extracranial bone metastases were stable, without obvious adverse effects. This is the first report of abemaciclib combined with fulvestrant in the treatment of cystic brain metastases in a patient with HR+/HER2 − breast cancer.
A Geospatial Analysis of the Relationship Between Land Surface Temperature and Land Use/Land Cover Indices in Raiganj Municipality, West Bengal, India
Authors: Sarkar Bapi , Patra Sribas
Published: March 2022

The current research focuses on estimating land surface temperature (LST) in Raiganj Municipality, India, with their relationships of different land use and land cover (LULC) indices such as Normalized difference vegetation index (NDVI), Normalized difference water index (NDWI), and normalized difference built-up index (NDBI). Data were pre-processing Using ERDAS Imagine 14 and Arc GIS 10.3 software for layer stacking, mosaicking and clipping of the Landsat images. The analysis was based on Landsat TM 5 and Landsat 8 OLI satellite images of 2001, 2011, and 2021.The study observed that the values of LST, and NDBI were increased by 0.9˚C, and 0.71 from 2001 to 2021. And the values of NDVI, and NDWI were decreased by -0.20, and − 0.34 from 2001 to 2011. High land surface temperature is primarily located on the buildup area and LST level is low significantly due to the presence of vegetation and water bodies. The result indicates relationship between LST and the LULC indices, while LST has a significant positive association with NDBI, while NDVI and NDWI have a moderate to strong negative correlation. The study also found that changing land surface temperature has a significant influence on the ecosystem and loss of green space.
Hepatit C’ye bağlı siroz hastalarında hepatosellüler karsinom gelişiminde öngördürücü faktörlerin retrospektif analizi
Authors: TÜRKER Fatih , ÇAVUŞOĞLU Betül , ŞAHİN Tolga
Published: March 2022

Amaç: Bu çalışmanın amacı kronik hepatit C’ye bağlı siroz hastalarında, hepatosellüler karsinom (HSK) gelişimini etkileyen faktörlerin değerlendirilmesidir.Yöntemler: Ocak 2010-Ocak 2020 yılları arasında T.C. Demiroğlu Bilim Üniversitesi Tıp Fakültesi Gastroenteroloji ve İç Hastalıkları polikliniklerinde hepatit C virüsüne (HCV) bağlı karaciğer sirozu nedeniyle takip edilen 18 yaş üstü 119 hasta çalışmaya dâhil edildi. Hastalar HSK’nin eşlik ettiği siroz ve HSK’ye eşlik etmeyen (non-HSK) siroz olguları olarak iki gruba ayrıldı. Biyokimyasal parametreler, demografik karakteristikler, MELD (Son Dönem Karaciğer Hastalığı Modeli) ve CHILD (Child-Pugh) skorları ve metabolik parametreler (vücut kitle indeksi [VKİ], metabolik sendrom) her iki grup için değerlendirildi. Bulgular: Hastaların 48’i HSK ve 71’i ise non-HSK siroz idi. Hastaların yaş ortalaması 55,9±7,7 ve 68’i erkek, 51’i kadındı. HSK ile non-HSK grupları karşılaştırıldığında ortalama yaş, erkek cinsiyet ve metabolik sendrom varlığı, HSK grubunda istatistiksel olarak anlamlıydı. MELD ve CHILD skorları, Uluslararası Düzeltme Oranı (International Normalized Ratio: INR) değeri, total bilirubin, kan üre azotu (Blood Urea Nitrogen: BUN) değerleri HSK grubunda daha düşük ve hemoglobin, hematokrit, Alanin Aminotransferaz (ALT), Gama Glutamil Transferaz (GGT) ve albumin değerleri HSK grubunda anlamlı derecede yüksek saptandı. Komplikasyon gelişimi yönünden karşılaştırıldığında hepatik ensefalopati, spontan bakteriyel peritonit, asit gelişimi HSK grubunda istatistiksel olarak anlamlı derecede düşüktü. ALT, artmış albümin düzeyi ve metabolik sendrom varlığının HSK oluşumunu öngördürebilecek bağımsız risk faktörü olduğu görüldü.Sonuç: ALT, artmış albümin düzeyi, metabolik sendrom varlığı HCV bağlı siroz hastalarında HSK gelişimi için önemli birer belirteç olabilirler.
Romarias e práticas devocionais ao Padre Cícero e à Mãe das Dores em tempos de pandemia
Authors: Batista Alencar Yslia , Marinho Paz Renata
Published: March 2022

Neste artigo, analisamos os impactos da pandemia da Covid-19 sobre as crenças e práticas religiosas dos devotos do Padre Cícero e de Nossa Senhora das Dores, bem como percepções dos romeiros sobre a pandemia. A pesquisa, desenvolvida entre setembro de 2020 e março de 2021, baseou-se na interação junto a grupos de romeiros em redes sociais na internet. Apresentamos uma reflexão sobre o processo de realização de pesquisa, com seus limites e possibilidades, bem como sobre as visões dos nossos interlocutores sobre a pandemia, e como vêm sendo desenvolvidas suas práticas religiosas, especialmente aquelas relacionadas à devoção ao Padre Cícero. Trazemos também uma análise acerca das impressões dos romeiros sobre a pandemia e suas associações às prédicas escatológicas do Padre Cícero. Por fim, apresentamos percepções sobre o processo constante de recriação das romarias, agudizado neste cenário pandêmico.
Estratégias de devotos e brincantes para a religiosidade em tempos de pandemia
Authors: Soares da Silva Cicera Tayane , De Lima Alves José Felipe , Freires de Meneses Itamara
Published: March 2022

As manifestações populares e religiosas tiveram suas dinâmicas modificadas com o surgimento da pandemia do Coronavírus, instaurada no Brasil em março de 2020, mas vivenciada por alguns países antes disso. A partir de uma conjuntura que trouxe consequências a nível mundial, observamos transformações nos aspectos: econômicos, sanitários, políticos e culturais. Devido a necessidade do isolamento social para conter as infecções causadas pelo vírus, as celebrações, algumas centenárias, tiveram que aderir ao processo de distanciamento social, provocando o cancelamento de romarias, eventos religiosos e festivos, comprometendo assim toda a agenda de diversos acontecimentos que caracterizam a cultura popular no Nordeste brasileiro.
LO QUE IMPORTA ES LA INTENCIÓN: LA CLÁUSULA DE MEJORES ESFUERZOS (BEST EFFORTS). APUNTES DESDE EL DERECHO PERUANO HACIA EL DERECHO COMPARADO
Authors:   Pontificia Universidad Católica del Perú, Lima, Perú, García Long Sergio
Published: March 2022

El presente artículo estudia a la cláusula best efforts de origen anglosajón, y en específico, conforme al derecho inglés y americano, a efectos de analizar cómo dicha cláusula podría ser entendida cuando es pactada en un contrato sometido a ley de una jurisdicción civilista.
RECTAL LYMPHOMA: A RARE CASE REPORT WITH REVIEW OF LITERATURE
Authors: . Sunigdha , Kang Manraj S , Garg Pardeep , Banipal Raja P S , Gupta Neha
Published: March 2022

Introduction: Colorectal lymphoma is an extremely rare disease. The disease is usually

diagnosed in the advanced stages because of its primary nonspecific symptoms. Treatment

modality of primary lymphoma of the rectum remains uncertain.

Case History: A 45-year-old male presented with rectal bleeding, pain in perianal region and

alteration in bowel habits along with fungating and circumferential mass in the rectum. The

histopathology and immunohistochemistry confirmed the diagnosis of Plasmablastic

Lymphoma. He was planned six cycles of CHOP regime. On follow up the residual disease was

managed with second line of chemotherapy (DHAP regimen). The patient was started on

Metronomic chemotherapy (Chlorambucil & Etoposide) in view of persistent residual disease.

Conclusion: Optimal treatment for rectal lymphoma needs to be established.
Heraldry and the early modern state
Authors: Ramsay Nigel
Published: March 2022

Review of Steven Thiry and Luc Duerloo, eds, Heraldic hierarchies. Identity, status and state intervention in early modern heraldry (Louvain: Leuven University Press, 2021, 273 p., ill.).
Adding Mobile Elements to Online Physical Activity Interventions Targeted at Adults Aged 50 Years and Older: Protocol for a Systematic Design
Authors: Collombon Eline H G M , Bolman Catherine A W , Peels Denise A , de Bruijn Gert-Jan , de Groot Renate H M , Lechner Lilian
Published: March 2022

Background

Physical activity (PA) can increase mental and physical health in adults aged 50 years and older. However, it has been shown that PA guidelines are often not met within this population. Therefore, our research group developed 2 computer-tailored intervention programs in the last decade to stimulate PA: Active Plus and I Move. Although these programs were proven effective, positive effects diminished over time and attrition rates were relatively high. To respond to this, we will integrate 3 interactive mobile elements into the existing programs: activity tracker, ecological momentary intervention program, and virtual coach app.

Objective

The goal of the research is to define systematic and evidence-based steps for extending our online computer-based PA intervention programs with 3 interactive mobile elements.

Methods

Components often included in other (eHealth) design models were identified as key components and served as a base for the definition of systematic steps: exploration of context, involvement of the target population, prototype and intervention testing, and implementation. Based on these key components, 10 systematic steps were defined. The initial step is a literature search, with the results serving as a base for development of the low-fidelity prototypes in step 2. The pilot phase comprises the 3rd to 6th steps and includes semistructured interviews, pilot tests, and adaptations of the prototypes with intensive involvement of the target population of adults aged 50 years and older, where particular attention will be paid to lower educated persons. The 7th step is an effect evaluation in the form of a randomized controlled trial. During the 8th step, the most effective intervention programs will be selected and reinforced. These reinforced intervention programs will be used during the design of an implementation plan in the 9th step and the subsequent field study in the 10th step.

Results

The project will be executed from December 2019 to December 2023. During this period, the systematic approach presented will be practically executed according to the methodological procedures described.

Conclusions

Based on the 4 identified key components, we were able to design an evidence-based systematic design approach for separately adding 3 mobile elements to our existing online PA intervention programs. The 10 steps are presented as a useful approach to guide future eHealth design studies.

International Registered Report Identifier (IRRID)

DERR1-10.2196/31677
Safety of Triage Self-assessment Using a Symptom Assessment App for Walk-in Patients in the Emergency Care Setting: Observational Prospective Cross-sectional Study
Authors: Cotte Fabienne , Mueller Tobias , Gilbert Stephen , Blümke Bibiana , Multmeier Jan , Hirsch Martin Christian , Wicks Paul , Wolanski Joseph , Tutschkow Darja , Schade Brittinger Carmen , Timmermann Lars , Jerrentrup Andreas
Published: March 2022

Background

Increasing use of emergency departments (EDs) by patients with low urgency, combined with limited availability of medical staff, results in extended waiting times and delayed care. Technological approaches could possibly increase efficiency by providing urgency advice and symptom assessments.

Objective

The purpose of this study is to evaluate the safety of urgency advice provided by a symptom assessment app, Ada, in an ED.

Methods

The study was conducted at the interdisciplinary ED of Marburg University Hospital, with data collection performed between August 2019 and March 2020. This study had a single-center cross-sectional prospective observational design and included 378 patients. The app’s urgency recommendation was compared with an established triage concept (Manchester Triage System [MTS]), including patients from the lower 3 MTS categories only. For all patients who were undertriaged, an expert physician panel assessed the case to detect potential avoidable hazardous situations (AHSs).

Results

Of 378 participants, 344 (91%) were triaged the same or more conservatively and 34 (8.9%) were undertriaged by the app. Of the 378 patients, 14 (3.7%) had received safe advice determined by the expert panel and 20 (5.3%) were considered to be potential AHS. Therefore, the assessment could be considered safe in 94.7% (358/378) of the patients when compared with the MTS assessment. From the 3 lowest MTS categories, 43.4% (164/378) of patients were not considered as emergency cases by the app, but could have been safely treated by a general practitioner or would not have required a physician consultation at all.

Conclusions

The app provided urgency advice after patient self-triage that has a high rate of safety, a rate of undertriage, and a rate of triage with potential to be an AHS, equivalent to telephone triage by health care professionals while still being more conservative than direct ED triage. A large proportion of patients in the ED were not considered as emergency cases, which could possibly relieve ED burden if used at home. Further research should be conducted in the at-home setting to evaluate this hypothesis.

Trial Registration

German Clinical Trial Registration DRKS00024909; https://www.drks.de/drks_web/navigate.do? navigationId=trial.HTML&TRIAL_ID=DRKS00024909
Self-reliance, Social Norms, and Self-stigma as Barriers to Psychosocial Help-Seeking Among Rural Cancer Survivors With Cancer-Related Distress: Qualitative Interview Study
Authors: DeGuzman Pamela Baker , Vogel David L , Bernacchi Veronica , Scudder Margaret A , Jameson Mark J
Published: March 2022

Background

Even when technology allows rural cancer survivors to connect with supportive care providers from a distance, uptake of psychosocial referrals is low. Fewer than one-third of participants in a telemedicine intervention for identifying rural survivors with high distress and connecting them with care accepted psychosocial referral.

Objective

The purpose of this research was to examine the reasons for which rural cancer survivors did not accept a psychosocial referral.

Methods

We utilized a qualitative design to address the research purpose. We interviewed participants who had been offered psychosocial referral. Semistructured interviews were conducted 6 weeks later (n=14), and structured interviews were conducted 9 months later (n=6). Data were analyzed descriptively using an inductive approach.

Results

Ultimately, none of the rural cancer survivors (0/14, 0%) engaged with a psychosocial care provider, including those who had originally accepted referrals (0/4, 0%) for further psychosocial care. When explaining their decisions, survivors minimized their distress, emphasizing their self-reliance and the need to handle distress on their own. They expressed a preference for dealing with distress via informal support networks, which was often limited to close family members. No survivors endorsed public stigma as a barrier to accepting psychosocial help, but several suggested that self-stigma associated with not being able to handle their own distress was a reason for not seeking care.

Conclusions

Rural cancer survivors’ willingness to accept a psychosocial referral may be mediated by the rural cultural norm of self-reliance and by self-stigma. Interventions to address referral uptake may benefit from further illumination of these relationships as well as a strength-based approach that emphasizes positive aspects of the rural community and individual self-affirmation.
Pendampingan Optimalisasi Pekarangan Dengan Konsep Smart Agriculture
Authors: Raya Alia Bihrajihant , Kriska Mesalia , Kastono Dody , Wulandari Nurul Trya , Septijono M. Puji Tri , Handayani Valentina Dwi Suci , Nugroho Agus Dwi
Published: March 2022

The main problems of the community in the Poncosari Village are they do not know how to optimally the local potentials and do not know the development of information technology. The aims of this activity are to optimize the potential of the garden in Poncosari Village for agricultural activities and the empowerment of farmer women groups in Poncosari Village in managing smart agriculture. This activity was carried out in Poncosari Village, Srandakan Subdistrict, Bantul Regency in March until August 2019. The method used was a Focus Group Discussion, counseling, training and assistance, demonstration plot, and evaluation and monitoring. The results of this activity show that most people have started to cultivate their gardens with vegetables. The Poncosari Village community also began to recognize and actively use the Desa Apps to consult farming and marketing issues.
First Report of Phytopythium vexans (de Barry) Abad, de Cock, Bala, Robideau, Lodhi & Lévesque Causing Potato Tuber Rot in Indonesia
Authors: Santika Islaminati Anna , Widiastuti Ani , Wibowo Arif
Published: March 2022

Phytopythium vexans (de Barry) Abad, de Cock, Bala, Robideau, Lodhi & Lévesque was successfully isolated from the soil of the potatoes field in Ngablak, Magelang. This research aimed to obtain the knowledge and potency of P. vexans as a pathogen in potatoes, identify the morphology and molecular of P. vexans compared with the Oomycetes, Phytophthora and Pythium. The morphological observation was conducted based on a macroscopic colony pattern that grew for five days on the PDA medium and microscopic observation on its hyphae, sporangia, papillate, and chlamydospore. The molecular identification was conducted using multigene analysis, ITS and LSU. The in vitro pathogenicity test was obtained by inoculating P. vexans inoculum to the healthy potatoes leaves and tubers. The results of morphological observation showed that P. vexans had a stellate pattern, aseptate hyphae, and sporangium with an ovoid shape completed with semipapillate. Chlamydospore as a survival form was also found. This research revealed that the morphology of P. vexans was between Pythium and Phytophthora. Whereas, based on the molecular analysis using ITS and LSU, the Phytopythium spp. are more closely related to Phytophthora spp. rather than Pythium spp. The pathogenicity test of P. vexans showed that it could infect the flesh of potato tubers showing a brown lesions symptom
НЕКОТОРЫЕ АСПЕКТЫ РАЗВИТИЯ ГРАЖДАНСКОЙ ЭЛЕКТРОНИКИ НА ПРИМЕРЕ ДЕЯТЕЛЬНОСТИ АО «НИИЭТ»
Authors: Куцько П.
Published: March 2022

Рассматриваются некоторые практические аспекты выхода на гражданский рынок электроники, ниши и окна возможностей, которыми могут воспользоваться российские предприятия, на примере деятельности АО «НИИЭТ» по развитию гражданской продукции.
НОВЫЙ ЭФФЕКТИВНЫЙ СПОСОБ ОПТИМИЗАЦИИ СИГНАЛЬНОЙ ЦЕПИ С ПОМОЩЬЮ СИГМА-­ДЕЛЬТА АЦП С НЕПРЕРЫВНЫМ ВРЕМЕНЕМ ПРЕОБРАЗОВАНИЯ
Authors: Рейс Б.
Published: March 2022

В статье рассмотрено использование сигма-­дельта АЦП с непрерывным временем преобразования (CTSD) в качестве нового способа оптимизации схемного решения, снижения количества используемых электронных компонентов и уменьшения форм-фактора.
ДЛЯ ПРОИЗВОДСТВА СЛОЖНОЙ СОВРЕМЕННОЙ ВЫЧИСЛИТЕЛЬНОЙ ТЕХНИКИ НУЖНЫ ЛУЧШИЕ ТЕХНОЛОГИЧЕСКИЕ РЕШЕНИЯ. ВИЗИТ НА ПРОИЗВОДСТВО ПАО «РИКОР ЭЛЕКТРОНИКС»
Authors: Ковалевский Ю.
Published: March 2022

Одной из активно развивающихся областей производства электроники в России сейчас является изготовление вычислительной техники. Требования по локализации аппаратуры, ограничения, введенные в отношении закупки вычислительных устройств для государственных и муниципальных нужд, и в целом взятый в нашей стране вектор на цифровизацию экономики и обеспечение технологической независимости вызвали существенный рост объемов изготовления на российских предприятиях таких изделий, как серверы, системы хранения данных, рабочие станции, ноутбуки, планшеты, что, в свою очередь, привело к необходимости наращивания производственных мощностей предприятий и модернизации производств для обеспечения возможности изготовления таких устройств на передовом уровне. Мы побывали на производственной площадке ПАО «Рикор Электроникс», расположенной в Арзамасе, где недавно была произведена такая модернизация – ​именно с целью наращивания объемов производства вычислительной техники. В прошлом году компания ввела в строй две новые линии поверхностного монтажа и линию селективной пайки, а сейчас ожидает прибытия оборудования еще для двух SMT-линий.
Аналитический контроль литиевой продукции в центральной заводской лаборатории Новосибирского завода химконцентратов
Authors: Лукина Е.А.
Published: March 2022

Аналитический контроль литиевого производства Новосибирского завода химконцентратов осуществляется в экспресс-­лаборатории. В ее распоряжении три спектрометрических комплекса для проведения анализа методом пламенной фотометрии. Объект анализа – технологический раствор, который может содержать целевые элементы в широком диапазоне концентраций. Для определения содержаний в диапазоне 0,01–5 мг / л используется модернизированный спектрометр «С‑115» с анализатором МАЭС. Образцы с концентрациями элементов в диапазоне 0,1–100 мг / л исследуют на спектрометре «Павлин», а с высокими содержаниями (до 70 г / л) – на спектрометрическом комплексе «Колибри‑2». ПО «Атом» обладает обширными возможностями.
Анализ микрочастиц пластиков с помощью лазерной системы визуализации химического состава Agilent 8700 LDIR
Authors: Мельник М.И.
Published: March 2022

Agilent разработал для анализа микрочастиц пластиков новое, не имеющее аналогов оборудование и метод визуализации химического состава на основе прямой лазерной ИК-спектроскопии – ​Agilent 8700 LDIR. Agilent 8700 LDIR с автоматизированной методикой программы Agilent Clarity опробован на реальных образцах, отобранных в Индийском океане с помощью системы фракционирования микрочастиц пластиков Geesthacht. Он показал высокую эффективность и надежность для поиска и характеризации микрочастиц и микроволокон пластиков в различных образцах.
Cuentos y relatos indígenas (Vol. 4)
Authors: Calvo Sánchez Angelino , López Díaz Miguel , Cruz Sántiz Francisco , López Hernández Higinio , Girón Guzmán Pedro , López López Ignacio , Gómez Entzin Rosendo , López Méndez Sebastián , Gómez García Manuel , Martínez Alfredo E. , Gómez Hernández Antonio , Méndez Maldonado Jacinto , Gómez Hernández Juan , Méndez Méndez Jacinto , Gómez López Andrés , Meneses M. Domingo , Gómez Sántiz Feliciano , Oleta Lara Lisandro , Hernández Gómez Manuel , Ruiz Ortiz Juana María , López Cruz Rosa , Ruiz Vázquez Marcos
Published: March 2022

En esta publicación se puede testimoniar la vitalidad de las lenguas indias de Chiapas como instrumentos versátiles para la creación literaria o histórica y a los actuales indios como capaces de crear y recrear sus realidades.
Occidente vs Oriente: factores cívico-políticos que conducen a resultados diferenciados frente al SARSCoV2
Authors: Añorve Añorve Daniel , Rosas González María Cristina
Published: March 2022

Los impactos por el SARSCoV2 han sido diferenciados geográficamente. En términos generales, las mayores tasas de contagios, decesos y letalidad tienen lugar en Occidente en oposición con lo observado en Oriente. Se aborda la pandemia desde la cultura cívico-política a partir del predominio que el individuo tiene en las naciones occidentales frente a la relevancia que posee la colectividad/comunidad en las orientales. Se analizan 11 países conforme a la tipología de Samuel Huntington: cuatro occidentales, cinco países no-occidentales y dos países escindidos o híbridos. Se sugiere que los países donde las libertades cívico-políticas en torno a la colectividad predominan, han tenido una menor incidencia de contagios/decesos durante la actual pandemia El análisis revela la importancia de la cultura cívico-política para hacer frente a emergencias como la pandemia del SARSCoV2.
Review on Designing and Development of Loading and Unloading Platform for Two Wheelers
Authors: Mujbaile Vedanand N. , Kalamkar Akash G. , Alagatu Akshay K. , Sonewane Ashish N. , Mahajan Kapil S. , Nagpure Sumit D. , Thakre Vedprakash S. , Sayankar Vinit D.
Published: March 2022

Abstract: Lift is a simple device use to raise the object from ground level to a certain height to perform a specific work with aiming of possible maximum load and minimum efforts. Lifts are generally operated either hydraulic, pneumatic or mechanical type. In many vehicle manufacturing industries, there are using lifting mechanism for loading and unloading operations which have to invest a huge capital for installing a exsisting bulkey and large platform which generally based on hydraulic means. This type of machine uses while export and import business. The main purpose of our study is to design and develop loading and unloading platform for two wheelers. Material selection plays important role in designing a machine and also influence on several factor such as strength, reliability, durability and resistance which leads to increase the life of lift. The aim of the project is to design and development of wire rope operated platform which lifts maximum 877.5 kg load including factor of safety with minimum time and labour for per cycle operation. Platform movement is achieved safely by using wire rope with the help of motor and drum assembly mechanism is of 2.8 m from the ground level. The design is performed by considering a mechanical lift as a portable, suitable for all type of load application and without any hydraulic or pneumatic means. The design is developed keeping in mind that consideration of all safety parameters. Lubrication required in few moving parts only. The aim of this paper is design, analysis and fabrication of a prototype mechanical lift which operate efficiently, consistently, sholud be easy to handle, multifunctional, cost effective, compact in size. Drafting and drawing of loading and unloading mechanical lift carried out in AUTOCAD with suitable modeling. The analysis of mechanical lift includes total deformation load, reaction forces, buckling and bending failures, equivalent stresses were done in ANSYS Software. Finally this analysis of strength, toughness, elasticity and temperature distribution is carried out in order to check the coherance of the design value. Keywords: Lifting Mechanism, Platform, Machine, Design and Development, Analysis, AUTOCAD, ANSYS Software.
Use of Primary Steel Rebar and Its New Techniques Used in High-Rise Building in Construction Industries: A Review
Authors: Saxena Devashish , Vishwakarma Arvind , M. Vignesh
Published: March 2022

Abstract: Steel concrete composite structures have gained widespread recognition worldwide for the construction of various types of structure. The steel utilise by various industries in India is less comparing to other developed country. The various types of steel rebar are used in the construction and some are in research mode. The various steel industries are to target to achieve the maximum strength and durability with satisfy the properties of steel bars. The articles deals with review of various research papers related to new approach adopted for construction of structure for steel bars in the concrete structure. Based on the various paper surmise report is prepared. The review of articles concluded that it is demand of current industry to assist and evolutes the primary bars and new techniques for advanced technology. Keywords: Primary Bar, Concrete Structure, New Techniques, Construction Material, strength and durability
PERMANECER OU SAIR DO MEIO RURAL? O DILEMA DOS JOVENS GRADUANDOS DO MUNICÍPIO DE CERRO LARGO/RS
Authors: Marian Tiherro Ricardo , Dalcin Dionéia , Ruschel Anes Carlos Eduardo
Published: March 2022

Os jovens rurais passaram a ser foco de estudos devido a suas particularidades, em especial pela continuidade das atividades do meio rural que depende deles, a sucessão familiar. Ao abordar os jovens rurais, é necessário considerar sua pluralidade, existência de uma polissemia de temas e abordagens como é indicado pela própria categoria plural, dentre elas a decisão após uma graduação. Os jovens provenientes do campo, agora ligados ao conhecimento e a qualificação, enfrentam um impasse entre continuar na vida do campo, ou irem em busca de novos caminhos e oportunidades de conhecimento. Assim, o estudo buscou analisar os fatores que interferem na tomada de decisão dos jovens rurais, graduandos do município de Cerro Largo/RS, em permanecer ou sair do meio rural. Metodologicamente, o estudo é constituído de uma pesquisa quantitativa, realizada por meio da aplicação de questionário com 90 estudantes. Os dados foram analisados através da estatística descritiva. Como resultado, é possível dizer que a aproximação entre o urbano e o rural despertou nos jovens a vontade de viver muitas vezes uma ligação entre os dois “mundos”. Apesar desse vínculo, ainda há uma preocupação com o êxodo rural juvenil, principalmente em relação às moças. Concluiu-se que os principais fatores para a tomada de decisão pela evasão, pelos jovens respondentes, são: a propriedade ser capaz de manter os filhos em atividade, a quantidade de hectares das propriedades, a desigualdade de gênero, e a noção de que a “vida urbana” possui mais liberdade e recursos tecnológicos.
Shifting Surgical Archetypes of ICG Fluorescent-Angiography for Bowel Perfusion Assessment in Cardiogenic Shock Under ECMO Support
Authors: Aleman Rene , Labkovski Matthew , Patel Sinal , Zadneulitca Nikita , Frieder Joel S. , Rosenthal Raul J. , Sheffield Cedric , Navia Jose , Brozzi Nicolas
Published: March 2022

Extracorporeal membrane oxygenation (ECMO) has been adopted to support
patients with acute severe cardiac or pulmonary failure that is
potentially reversible and unresponsive to conventional management. In
the presence of pulmonary embolism, mesenteric ischemia (MI) can present
as a life-threatening disorder that leads to intestinal ischemia. Due to
the nature and acuity of these conditions, determining adequate
perfusion upon surgical intervention is challenging for the operating
surgeon, especially in the presence of cardiogenic shock despite ECMO
support. Indocyanine green fluorescent angiography (ICG-FA) has proven
to be useful for real-time vascular perfusion assessment, which may
potentially decrease the rate of development of perfusion-related
complications. The case report here-in presented, breaks the paradigm of
performing noncardiac surgical procedures on ECMO support via a
pioneering visual aid technique. Learning objective Indocyanine green
fluorescent angiography (ICG-FA) is a promising visual trans-operatory
technique providing real-time feedback for the adequate identification
and assessment of target tissue/organs. The high morbidity and mortality
rates associated to MI and CS – particularly when concomitantly present
– hinders salvage surgical therapy. The use of acute ECMO provides
stabilization yet lacks any curative solutions. This case report
highlights the importance of adequate surgical intervention under
extracorporeal life support in the presence of both CS and MI. To the
authors’ knowledge, said approach has never been attempted, yet trails a
promising therapy for the improvement of associated mortality rates.
Remote-sensing-based monitoring the dynamics of Kyagar Glacial Lake in the upstream of Yarkant River, north Karakoram
Authors: Yunyi Luo , Liu Qiao , Zhong Yan , Han Wang
Published: March 2022

Long-term monitoring of ice-dammed lake development are important for
understanding the process of lake storage and outburst. Based on remote
sensing observations for the period 1972-2020, we obtained so far the
most detailed reconstruction of the filling and drain of Kyagar lake, a
typical annually ice-dammed lake in the north Karakoram. We show that
annually repeated lake filling-drains were detected by satellite
observations during two periods:1996 to 2009 and 2015 to 2020, while
between 2009 and 2015 none obvious outburst occurred. These two
intermitted periods with regular annual cycles of lake outburst were
likely related to the long-term cycle of glacier surge dynamics, which
show two remarkable surge-induced terminus accelerations during
1995-1997 and 2014-2016. Following each surge, the maximum lake areas
were decreased by about 33% from 1996-2009 and by about 88% from
2015-2020. With climate warming and the thinning of the ice-dam, the
storage capacity of glacial lake will likely continue decrease in the
future, and the risk of lake outburst flood thus somehow decrease.
Repeated drainage following filling exacer-bates the depletion of
material at the glacier terminal, leading to the cessation of storage
and creating the conditions for the next glacial surge to occur, thus
creating a long-term cycling process. Together with the uncertainty and
intensified climate changes, it suggests that a close monitoring of the
glacial lake development and glacier dynamics would be still important.
Effects of different nano size and bulk WO3 enriched by HDPE composites on attenuation of the X-ray narrow spectrum
Authors: Obeid Amro , El Balaa , El Samad , Alsayed Zainab , Awad Ramadan , Badawi Mohamed
Published: March 2022

The X-rays of the narrow-spectrum N-series ranging from 40 kV to 150 kV were
used to determine the radiation attenuation ability of a new category of a
polymer composite fabricated for shielding purposes. High density
polyethylene was synthesized through a compression molding technique, and
incorporated with various filler amounts (10, 15, 25, and 35 wt.%) of bulk
micro-sized WO 3 (Sample A), two WO 3 nanoparticles 45 nm (Sample B), and 24
nm (Sample C). The WO 3 filler was identified and characterized using X-ray
diffraction and a transmission electron microscope. The mass distribution of
the chemical elements of the synthesized composites was determined by
energy dispersive X-ray analysis. The obtained results of the different
attenuation parameters revealed that the particle size and weight fraction
of WO particles have an outstanding effect on the X-ray shielding ability of
this composite. The 3 experimental measurements of the mass attenuation
coefficients were compared to the theoretical values tabulated in the NIST
databases XCOM and FFAST. The mass attenuation coefficient was increased
with the increment of WO 3 wt.% as well as with the decrease of the WO 3
particle size. This improvement in the attenuation parameters of the NP(C)
composite suggests their promising applications in radiation protection at
the diagnostic level.
Effect of different phantom positions in lateral lumbar spine radiography on effective dose and absorbed dose to selected organs
Authors: Mekis Nejc , Alukic Erna
Published: March 2022

This study aimed to investigate the different positioning of the patient in
left and right lateral position during lumbar spine radiography and its
effects on effective dose and absorbed dose for selected organs. The study
was performed on a Siemens Multix/Vertix X-ray unit using Agfa's computer
radiography system. Two anthropomorphic phantoms (PBU 60 and RS 113T) were
imaged in both lateral projections with a tube voltage from 79 kV to 90 kV.
The dose was measured with a DAP meter placed under the collimator of the
X-ray unit. The effective dose and absorbed dose for selected organs were
calculated using the Monte Carlo simulation programme PCXMC 2.0. Based on
Monte Carlo simulation calculations, the results of effective dose on a PBU
60 phantom showed a decrease of 15.2%, while the decrease in effective
dose on a RS 113T phantom was 14.2% in favour of the right lateral
projection. An absorbed organ dose to selected organs showed a significant
dose reduction for lymph nodes, pancreas, small intestine, spleen, and
stomach in favour of this projection. Based on the results, we can
conclude that right lateral projection should be the method of choice when
imaging the lumbar spine in the lateral projection.
Effect of low-level laser therapy on the time needed for leveling and alignment of mandibular anterior crowding:
Authors: Ghaffar Yasmine Khaled Abdel , El Sharaby Fouad A. , Negm Ibrahim Mazen
Published: March 2022

Objectives

To assess the effect of low-level laser therapy (LLLT) on overall leveling and alignment time of mandibular anterior crowding and associated pain after initial archwire placement.

Materials and Methods

Thirty-two females (18-25 years) with mandibular anterior crowding were randomly allocated into laser and control groups. Eligibility criteria included Angle Class I molar relationship and Little's irregularity index (LII) from 4 to 10 mm. Randomization was accomplished with a computer-generated random list. A 0.014-inch copper-nickel-titanium (Cu-NiTi) wire was inserted immediately after bonding of 0.022-inch Roth brackets followed by 0.016-inch Cu-NiTi, 0.016 × 0.022-inch NiTi then 0.017 × 0.025-inch stainless steel wire after completion of alignment. In-Ga-As laser was applied to the mandibular anterior segment in the laser group on days 3, 7, and 14, then at 1 month followed by every 2 weeks until completion of leveling and alignment. Visual analogue scale questionnaires were completed by each patient over 7 days from initial archwire placement. Digital models were used to monitor changes in the irregularity index. Blinding was applicable for outcome assessors only.

Results

The mean time for leveling and alignment was significantly lower in the laser compared to the control group (68.2 ± 28.7 and 109.5 ± 34.7 days, respectively). The laser group displayed a significantly higher mean alignment improvement percentage as well as lower pain scores compared to the control group.

Conclusions

Within the constraints of the current study, LLLT has a potential for acceleration of anterior segment alignment as well as reduction of the pain associated with placement of initial archwires.