bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of noise levels of two micro-wind turbines using a randomised experiment
Authors: Clohessy Chantelle May , Brettanny Warren , Sharp Gary , Vorster Frederik
Published: June 2019

One of the more contentious environmental concerns of wind turbines is the wind turbine noise. This study assesses the noise impacts of two micro-wind turbines on the environment by comparing the noise generated by these turbines to traditionally accepted surrounding sounds. The sound level data was collected using a randomised experiment and fitted using a general linear model (GLM). The GLM was used to determine the relationship between the sound level generated at a given site to the time of day, the wind speed, the wind direction and a fixed predetermined distance from the sound source.
Kenneth Cobonpue, diseño de vanguardia desde Filipinas para el mundo
Authors: Olaya Buitrago Felipe , Carvajal Juan Diego
Published: June 2019

Cuando de creatividad se trata no siempre se requieren diseños complicados, podemos observar como Kenneth ha creado grandes productos inmobiliarios partiendo de la creatividad en el diseño y la innovación en los productos y sus materiales para la fabricación (como es el rattan sintético), que permiten mayor durabilidad y moldeabilidad en la fabricación.
Multiple extradigital glomus tumors of the ankle and foot with limb hypoplasia in a child: a case report
Authors: Lim Chiao Yee , Ng Sijie , Duski Suryasmi , Chye Ping Ching
Published: June 2019

Glomus tumors are rare tumors, and mostly occur in the fingertips and/ or subungual location. Multiple extradigital glomus tumors are extremely rare. We hereby described a rare case of multiple extradigital glomus tumor of the ankle and foot in a 11 year old girl with hypoplasia of the affected limb. The patient presented with swellings over her right ankle and foot for the past 5 years. The swellings were initially painless but became painful for the past 15 months. On examination, patient’s right leg and foot appeared to be smaller when compared to the left side. There were multiple vague swellings over the dorsum of right food and lateral aspect of right ankle, which were very tender to touch. There was no overlying skin changes observed. Magnetic resonance imaging showed multiple well defined, encapsulated lesions of varying sizes at the level of distal third right fibula and foot. The lesions appeared isointense to muscle in T1-weighted image, hyperintense in T2-weighted image with enhancement post-contrast. Excision biopsy of the right lateral distal leg swelling was performed. Histopathological examination of the excised mass confirmed the diagnosis of glomus tumor. In view of her parents were not keen for any further surgical intervention, the patient will be evaluated regularly, and any enlarging painful lesions will be excised as required. The clinical diagnosis of multiple extradigital glomus tumors is much more problematic due to its rarity. The physicians must be aware of this differential diagnosis so that early diagnosis and treatment could be administered to the patients.
Singaporean Societies: Multimedia Communities of Student Migration
Authors: Dang Xuan Thu , Nicholas Howard , Starks Donna
Published: June 2019

Studies of home language use tend to focus on macro-level language changes and verbal communication rather than on micro-level analyses of family communication. This makes it diffcult to form a nuanced picture of the relations among diverse resources deployed in transnational family communication. In this paper, we address this issue by reporting results from a preliminary study of the micro-level communicative interactions of a frst-generation transnational Australian Vietnamese family who have settled in Melbourne, Australia. Through an in-depth analysis of a 20-minute video clip, we capture intersections in the rich, diverse communicative resources used by the family as they watched a favourite English television program while simultaneously keeping in contact with family members overseas. Our analysis shows that transnational family communication patterns involve complex displays of language use, silence, touch, movement, and spatial orientation, which together enable the family to communicate in the here and now with individuals near and far. We use the multiplicity framework to interpret the fuidity of multimodal communication, intimacy, and continuity across space.
Rohingya Muslims in Malaysia: Finding (Imperfect) Heaven in Polymedia
Authors: Nisa Eva F
Published: June 2019

The condition of Rohingya Muslims, who for decades have faced a humanitarian crisis, especially in their homeland of Rakhine State, Myanmar, has attracted international attention and sympathy. This article focuses on Rohingya Muslims living in a transit country, Malaysia. Drawing on ethnographic feldwork conducted in Malaysia between 2015 and 2017, this article examines the efforts of Rohingya Muslims to reestablish familial bonds with relatives with whom they had lost touch as a result of a series of crises. The article analyses the role of polymedia in the life of Rohingya Muslims, particularly the impact of polymedia among youth and activists who centre their efforts on Rohingya Muslims. The article expands on the available work regarding the use of communication technologies in times of crisis by focusing on the ways in which young Rohingya Muslims use communication technologies to amplify their voices and establish a connected presence in their distributed and disrupted family lives. By claiming their place in a polymedia-rich environment, young Rohingya Muslims have found a “virtual heaven”—albeit an imperfect one—by embracing the freedom to use their voices through a wide variety of communication technologies. Living in their country of asylum, Malaysia, they can play a signifcant role as bridging agents who both raise awareness of the plight of Rohingya in Myanmar and work together with those living in resettlement countries to solve the complex problems arising from persecution, displacement, and statelessness.
Voice of Singapore’s Invisible Hands: Indonesian Migrant Domestic Workers and Poems on Home and Family
Authors: Rahajeng Mintarsih Adriana
Published: June 2019

Yoga Prasetyo, the son of an Indonesian migrant domestic worker (MDW) in Singapore, founded Voice of Singapore’s Invisible Hands (or The Voice) in late 2016. A nonproft organisation that aims to challenge the negative discourses about MDWs, especially among Singaporeans, The Voice uses Facebook to promote its members’ literary work and achievements, as well as to share stories to inspire migrant workers.
ARTICULATION OF WOMEN THROUGH THE LENS OF INTERSECTIONALITY AND ITS DIMENSIONS IN ‘ONE PART WOMAN’ AND ‘SINGAREVVA AND THE PALACE’
Authors: Saleh Alyahya Dr. Rimah
Published: June 2019

Purpose of the Study: This paper aims to articulate women through the lens of intersectionality and its dimensions in ‘One Part Woman’ and ‘Singarevva and the Palace’. The research addresses the issues faced by ideologically, culturally, and materially deprived women of the society.

Methodology: In order to achieve the purpose of the study, two novels, namely, ‘One Part Woman’ (by Perumal Murugan) and ‘Singarevva and the Palace’ (by Chandrasekhar Kambar), were critically analyzed.

Results: It is inferred that the two novels helped to understand the nature and variety of community, class, and gender. It is found that there is a difference in the community attitude towards the barrenness of women. In the case of ‘One Part Woman’, the community permits her to go to the chariot festival and choose any stranger to attain motherhood, whereas in the case of ‘Singarevva and the Palace’, the community does not allow her to attain motherhood outside her marriage. It is found that the gender of women is the cause of various oppressions due to which women’s rights are denied. It is inferred that Ponna and Singarevva transcend their marital relationships to attain motherhood. It is seen that female sexuality is meant only for motherhood and for the benefit of the progeny. Thus, women’s sexuality is also oppressed.

Implications: Women face distressful situations, agony, and pain arising out of patriarchal ties, such as caste, class, community, religion, sexuality, and gender. Women play the role of a mother, daughter, wife, sister, friend, etc. She deserves a better position and status in the society. The oppressions faced by women form hurdles in their lives. They are the care takers of the family and they need to be respected and given a good rank in the society.
A emergência da profissão do Educador Social: uma aproximação a partir dos processos de profissionalização
Authors: Canastra Fernando Augusto Coelho
Published: June 2019

A formação inicial dos Educadores Sociais, em Portugal, tende a ins-crever-se numa lógica difusa, tanto ao nível do perfil formativo-profis-sional, como ao nível do seu referente competencial. O propósito destacomunicação visa apresentar uma aproximação a um modelo formativo,tendo como matriz disciplinar específica a Pedagogia Social. Partindode um referencial de competências (Sáez, 2009), sugerimos uma ou-tra abordagem em relação à consolidação do exercício profissional dosEducadores Sociais. A crescente oferta formativa nesta área, ao nível doensino superior, exige que se produzam referentes partilhados no do-mínio conceptual, metodológico e deontológico. Caso contrário, a lógi-ca de “desprofissionalização” tenderá a impor-se nos diversos sectores de intervenção onde trabalha o(a) Educador(a) Social. A formação dosprofissionais de Educação Social deve centrar-se numa lógica profissio-nal. É a partir deste enfoque que temos vindo a investigar.
Observações sobre o mito e a educação moderna
Authors: Petronio Gianfranco
Published: June 2019

O mito é uma forma arcaica, pré-científica e, assim, aproximativa de conhecimento? Essa é a pergunta da qual toma pretexto a presente reflexão. A resposta, negativa, emerge após algumas observações centradas sobre a tese que considera o homem um ser já completamente humano desde o início da sua vivência existencial e histórica e, assim, capaz de colher e interpretar plenamente a essência do real. Corolário imediato dessa tese é a consideração do processo de aculturação (de acúmulo de instrumentos culturais) não como processo absolutamente progressivo, mas simplesmente modificativo, em última instância. O mito, então, dessa perspectiva, resulta ser uma visão direta do real, dos próprios fundamentos do real, que a humanidade conseguiu coletar e cristalizar. Um momento cognoscitivo de capital importância que a humanidade “sucessiva”, sobrecarregada de meios culturais técnico-científicos, está, de fato, impossibilitada de reencontrar e pode só parcialmente reconstruir. Mas se a experiência mítica direta é preclusa à humanidade moderna é, porém, ainda possível para qualquer ser humano na fase da infância. Cada nova geração, assim, pode abrir por um breve importantíssimo momento, a fresta do mito para toda a humanidade, mas isso só enquanto a estrutura educativa saiba fazer um passo atrás, não podendo ser metodologia e teoria formativa capazes de anular essa oportunidade insubstituível.
Afetividade em Contextos Educacionais e na Formação de Professores: Mobilizações, Participação Social e Sofrimento Ético-Político
Authors: De Mendonça Viviane Melo
Published: June 2019

Pretendeu-se traçar reflexões sobre a constituição do sujeito e da afetividade dentro do referencial teórico-metodológico da abordagem sociohistórica da psicologia, tendo como campo de análise a questão do sofrimento ético-político em contextos educacionais e na formação de professores. Concluiu-se que o desafio para a educação e para formação de licenciandos e professores é o de proposição de alternativas que possibilitem às instituições educativas repensarem suas práticas sociais com adolescentes e jovens de modo a produzir espaços direitos e respeito às diferenças.
Administração e Gestão Escolar: Adequação às Orientações Gerais do Capitalismo Contemporâneo
Authors: Santos Flávio Reis
Published: June 2019

O tema deste artigo, apesar de recorrente no contexto das pesquisas no campo educacional, ganha importância e relevância em razão do conjunto das reflexões expostas no âmbito do debate acerca da condução das políticas públicas de educação; na medida em que observamos que antigos problemas permanecem afetando, de forma negativa, tanto a gestão educacional e da escola, quanto à qualidade dos processos de formação que acontecem em seu interior. A continuidade de práticas na formulação e implementação de tais políticas podem residir na constante adequação da educação e da escola pública à heterogeneidade das demandas do mercado capitalista, na proporção em que o governo brasileiro se submeteu à orientação e interferência do Banco Mundial na administração das questões sociais.
As Missões Culturais no Estado do Rio de Janeiro e Sua Importância para a História da Educação Fluminense
Authors: Quaresma Marcia da Silva
Published: June 2019

Este texto procura analisar e refletir sobre as Missões Culturais realizadas no estado do Rio de Janeiro nos anos de 1944 e1945 sob o comando do Interventor Amaral Peixoto. As Missões Culturais foram inspiradas no movimento das Missões Culturais mexicanas,que se tornaram fonte de debates e estudos na década de 1940 e 1950, realizando também uma pequena comparação entre os dois tipos de missões. O Objetivo das Missões Culturais no estado do Rio de Janeiro era o de, através do cinema, palestras informais, oficinas práticas, visitas às residências e instituições, levar às comunidades visitadas informações sobre saúde, desenvolvimento econômico, civismo, além de conhecer e registrar a vida cotidiana e as necessidades dessa população;informando então ao chefe do governo estadual tais necessidades e solicitações. Este texto aborda aspectos fundamentais nas Missões Culturais e da sua importância para a história da educação fluminense.
Organismos Internacionais e Políticas de Educação Não Formal
Authors: Bendrath Eduard Angelo
Published: June 2019

A partir de uma visão centrada nas políticas públicas da educação, esse texto faz uma discussão conceitual da influência de organismos internacionais nos modelos formais e não formais de educação. A participação das agências financeiras e da UNESCO na implantação de reformas e programas em países em desenvolvimento é abordada, tendo como discussão central a implantação no Brasil do Programa Escola Aberta, do Governo Federal, em parceria com a UNESCO. Tal programa tem como objetivo a inserção das comunidades no âmbito escolar por meio da educação não formal, oferecendo a possibilidade de acesso a bens de cultura, qualificação profissional, esporte e saúde. Conclui-se que a educação não formal é vista como um campo em expansão, com especial atenção dos organismos internacionais, alicerçada principalmente por ações complementares de formação humana.
O Desafio Educacional, de Florestan Fernandes
Authors: Risso Antônio Luís , Gomes Sandra Regina , Bauer Carlos
Published: June 2019

A obra de Florestan Fernandes, sociólogo brasileiro, (1920 – 1995), é bastante vasta. Sua produção intelectual compreende mais de cinquenta títulos, abrangendo temas culturais, políticos, sociais, entre os quais figuram obras como A organização social dos tupinambás, A integração do negro na sociedade de classes, Sociedade de classes e subdesenvolvimento, Capitalismo dependente e classes sociais na América Latina, Em busca do socialismo – últimos escritos e outros textos-e A revolução burguesa no Brasil. Contemplando também temas educacionais, podemos encontrar, além de O desafio educacional, A universidade brasileira: reforma ou revolução, A questão da USP e Educação e sociedade no Brasil. O presente artigo preocupa-se em refletir sobre a importância histórica d’O desafio educacional, editado pela Cortez e Editores Associados, em 1989, na construção da práxis contra-hegemônica na educação brasileira.
Conscientização em um currículo de informática: Um estudo de caso de um modelo de informática comunitária em Bangalore, Índia
Authors: Byker Erik Jon
Published: June 2019

Políticas públicas na India asseveram que as Tecnologias de Informação e Comunicação (TICs) vem promovendo benefícios educacionais e provendo modos inovadores de educar crianças indianas em idade escolar. Entretanto, muitas das crianças na India não têm acesso nem mesmo a um único computador em suas escolas, ou onde habitam. Isso é especialmente comum nas áreas de favelas indianas, as quais frequentemente refletemo “efeito Matthew”, no qual os ricos se tornam mais ricos e os pobres mais pobres, baseados em seus níveis de acesso a recursos como tecnologia informática. O objetivo desse estudo é descrever e relatar a respeito de intervenções em tecnologia informática destinadas a jovens vivendo em favelas indianas. Especificamente, o artigo examina um estudo de caso de um esforço de base, chamado de modelo de informática comunitária em Bangalore, India. Esse modelo é um centro tutorial frequentado por jovens fora do horário escolar, que provê um currículo holístico de educação em informática, para ajudar os estudantes a aprenderem tanto sobre tecnologia informática como para usar o computador para transformar sua comunidade. Empregando o conceito de Paulo Freire de conscientização como estrutura teórica, o artigo analisa e discute as implicações que um modelo como esse, de informática comunitária, poderia ter em auxiliar as crianças de favelas indianas a desenvolver uma consciência crítica sobre problemas sociais, assim como a usar a tecnologia computacional com propósitos emancipatórios.
A responsabilidade social universitária nos currículos de engenharia
Authors: Hattum-Janssen Natascha van , Sanchéz-Fernandéz Maria , Caires Susana , Kahn Sheila
Published: June 2019

Este trabalho está integrado numa colaboração internacional entre quatro universidades, pertencentes a países diferentes, e pretende contribuir para uma comparação das perspectivas existentes entre Espanha, Portugal e México, para a inovação curricular na área professional de Engenharia. Neste artigo, iremos apresentar perspectivas comparadas dos alunos dos cursos de Engenharia de quatro Universidades Iberoamericanas: em Portugal, a Universidade do Minho; em Espanha, a Universidade da Coruña, e duas Universidades pertencem ao México- a Autónoma de Aguascalientese a de Guanajuato. Analisamos as percepções de alunos sobre o lugar da Responsabilidade Social no currículo dos cursos, analisando também o que é vivenciado e experienciado pelos alunos naquilo que diz respeito à Responsabilidade Social, no senso amplo no ambiente das experiências na sociedade em geral e específico no ambiente universitário. Para a coleta dos dados utilizamos o instrumento qualitativo denominado grupo focal. Este trabalho pretende contribuir para a inovação curricular e educacional, na Educação Superior. As preocupações com a Responsabilidade Social foram, em junho de 2012, debatidas em escala global pelo Rio+20. Urge debater a problemática da Responsabilidade Social Universitária (RSU), pois as instituições de Ensino Superior são agentes privilegiados no que diz respeito à sedimentação da importância da temática junto aos alunos, à ação docente e à sua gestão. A área de Engenharia, aqui tratada mais especificamente, é fulcral para a criação de um futuro sustentável, pois compõem atividades profissionais com grande impacto em termos da tríade da responsabilidade social, envolvendo conjuntamente seus aspectos ambientais, económicos e sociais.
A práxis educativa e o projeto político-pedagógico em abrigos para crianças e adolescentes
Authors: Izar Juliana Gama
Published: June 2019

O presente artigo busca resgatar a história nacional das práticas institucionais voltadas para o atendimento de crianças e adolescentes acolhidos e refletir acerca de seu papel educacional. Entendidos como espaços socioeducativos e garantidos pelo Estatuto da Criança e do Adolescente como uma medida de proteção, os abrigos nem sempre cumprem o seu papel principal que é a promoção do desenvolvimento integral dascrianças e adolescentes acolhidos. Nesse sentido, faz-se necessário mais que um reordenamento institucional. É imperativa a alteração de suas práticas educativas e, para tanto, o projeto pedagógico se destaca como instrumento possível para a fundamentação e norteamento de suas práticas. Assim, este artigo tem por objetivo apresentar a especificidade do projeto pedagógico (comum em espaços de educação formal) paraabrigos que se orientam pela prática da educação social.
Social responsibility in engineering curricula
Authors: Hattum-Janssen Natascha van , Sanchéz-Fernandéz Maria , Caires Susana , Kahn Sheila
Published: June 2019

Corporate Social Responsibility (CSR) is a concept related to the need for companies to be not only competitive but also sustainable and refers to and the relationship of the company with its social and environmental surroundings, including labour issues [1]. CSR is also gaining attention within Higher Education, being related to a wide range of activities taking place at universities, especially the environmental dimension [2].
Santa Maria Belém
Authors: Barbosa Severino Antonio Moreira
Published: June 2019

Poemas portugueses.
PROLOG & TXL: A Case Study for Prototyping Structural Testing Supporting Tools
Authors: Sugeta Tatiana , Simao Adenilso da Silva , Maldonado Jose Carlos , Monard Maria Carolina
Published: June 2019

Structured testing criteria are usually used to assess the adequacy of test case sets, defining coverage measures. Control and data flow based criteria employ information about the program graph as well as definition and usage of variables to establish the testing requirements. In this paper, we present an approach to prototype supporting tools for control and data flow based criteria. In the proposed approach, we use TXL — a language based in the transformational paradigm — to analyze and instrument the program under test. The instrumentation aims at making it possible to process the data by a Prolog program which allows the tester to assess the test case set adequacy. A simple example is used to illustrate the main ideas of our approach.
O princípio da motivação dos atos administrativos: regra meralmente formal ou pressuposto substancial de validade dos atos?
Authors: Faria Júlio Herman
Published: June 2019

Este artigo tem como objetivo demonstrar, à luz de alguns referenciaisteóricos do moderno Direito Administrativo e Constitucional, que o “Princípio da Motivação”, um dos ícones do Regime de Direito Público,extraído implicitamente do artigo 37 da Constituição Federal, e cuja imprescindibilidade à validade do ato administrativo remonta da Lei nº 4.717/65 — Lei de Ação Popular — é na verdade uma regra — e não um princípio. Além disso, em conseqüência, particularmente no âmbito do Direito Administrativo quanto ao dever de motivar os atos administrativos (Lei nº 4.717/65, art. 2º, d), não deve esta regra ser cumprida sob o aspecto meramente formal, mas tida, antes, como uma imposição cogente a todo agente público, seja o ato vinculado ou discricionário, motivação essa que deve expressar — de modo transparente e congruente — as verdadeiras razões de fato e de direito que motivaram as decisões. Desse modo, estaria sendo dada efetividade ao princípio da sindicabilidade dos atos administrativos, pois o cidadão possui um direito subjetivo a um governo eficiente, moral e transparente.
Factors associated with follow-up difficulty in longitudinal studies involving community-dwelling older adults
Authors: Kawai Hisashi , Ejiri Manami , Tsuruta Harukazu , Masui Yukie , Watanabe Yutaka , Hirano Hirohiko , Fujiwara Yoshinori , Ihara Kazushige , Tanaka Masashi , Obuchi Shuichi
Published: June 2019

Background

To clarify the factors associated with the gradual drop-out from society in older adults, we defined the stages of follow-up difficulty based on four follow-up surveys on non-respondents of longitudinal mail surveys in community-dwelling older adults. This study aimed to examine the main factors associated with the stages of follow-up difficulty.

Methods

We conducted a follow-up mail survey (FL1) aimed at the baseline respondents and conducted follow-up surveys on non-respondents of each survey as follows; simplified mail (FL2), post card (FL3), and home visit surveys (FL4). The respondents of each follow-up survey were defined as a stage of follow-up difficulty and their characteristics concerning social participation and interaction at the baseline in each stage were analyzed.

Results

The respondent numbers of the FL1, FL2, FL3, and FL4 and NR (non-respondents) stages were 2,361; 462; 234; 84; and 101 respectively. Participation in hobby groups for FL2 and FL3, in sports groups in FL4, and for the neighborhood association and social isolation in NR were significantly associated with the stage of follow-up difficulty.

Conclusions

Based on these results, we conclude that the factors associated with each stage of follow-up difficulty are: 1) their activities start to be restricted by a decline in IADL in the FL2 and FL3 stages, 2) they dislike taking part in physical activity such as sports in the FL4 stage, and 3) they are more socially isolated, not belong to even a neighborhood association owing to be low social interaction in the NR group.
Whole-transcriptome analysis of heart in bovidae reveals regulatory pathways associated with high-altitude adaptation
Authors: Wang Hui , Zhixin Chai , Jincheng Zhong , Zhi Chen , Jiangjiang Zhu , Jikun Wang , Chengfu Zhang , Hanwen Cao , Jinwei Xin
Published: June 2019

Background: the yak (Bos grunniens) is one of the major livestock that can survive the extremely cold, harsh and oxygen-poor conditions and provide meat, milk and transportation for Tibetans living in the Qinghai-Tibetan Plateau, and there are some cattle migrate to yak habitat but cannot survive the extremely conditions well. However, the regulatory mechanisms that drive hypoxic adaptation of yak remain elusive.
Results: Thus, we collected heart tissues from Leiwuqi (LWQ) yak and their relatives, the migration cattle in LWQ yak habitat (HAC) and low-altitude cattle (LAC), respectively, for RNA sequencing, 178 co-differentially expressed protein-coding transcripts (CETs) including 6 down-regulated and 172 up-regulated CETs were discovered in both LAC-vs-LWQY and LAC-vs-HAC comparison groups. There were 133, 11 and 3 lncRNA transcripts were specific expressed in LWQY, HAC, and LAC groups, respectively. 2 and 230 lncRNA transcripts differentially expressed in LAC-vs-LWQY and LAC-vs-HAC，respectively, but no lncRNA transcripts co-differentially expressed in those two comparison groups. Among the 58 miRNAs that were co-differentially expressed, 18 were up-regulated and 40 were down-regulated. In addition, 640 (501 up-regulated and 139 down-regulated) and 152 (152 up-regulated and 1 down-regulated) circRNAs showed differential expression in LAC-vs-LWQY and LAC-vs-HAC comparison groups, respectively, and 53 up-regulated co-differentially expressed circRNAs were shared. Multiply CETs which are the target genes for miRNAs/lncRNAs were significantly enriched in high-altitude adaptation related processes, for instance, T cell receptor signaling, VEGF signaling, and cAMP signaling. A competing endogenous RNA (ceRNA) network by integrating competing relationships among CETs, miRNAs, lncRNAs and circRNAs were constructed. Furthermore, we constructed a hypoxic adaptation related ceRNA network to identified that 8 miRNAs and 15 circRNAs were predicted to regulated MAPKAPK3, PXN, NFATC2, ATP7A, DIAPH1 and F2R genes.
Conclusion: In conclusion, our data reinforce the view that the molecular network of high-altitude adaptation is composed of several protein-coding transcripts and non-coding transcripts that involved in multiply hypoxic adaptation regulatory pathways. The detailed mechanism for how this network crosstalk each other in heart of Bovidae are worthy of future research efforts.
Vibration experiments for diagnostic investigations on a glass suspension footbridge
Authors: Bedon Chiara , Bergamo Enrico
Published: June 2019

Structural glass represents a relatively innovative and not well-known solution for constructions, where it is largely used for facades, roofs, footbridges, etc. There, multiple (sandwich) glass members can interact with traditional building materials, and should offer appropriate fail-safe performances, within the full life time. However, severe operational conditions, or extreme loads, can increase the intrinsic vulnerability glazing systems. In this paper, the dynamic characterization and damage diagnostic assessment of an existing glass footbridge is carried out, based on Operational Modal Analysis (OMA) techniques.
Study of the area of attraction of the auto-balancing mode in a ball-type automatic balancing device with a horizontal axis of rotation
Authors: Strautmanis Guntis , Mezitis Mareks , Strautmane Valentina , Gorbenko Alexander , Shchukins Igors , Gromova Marina
Published: June 2019

It is known that automatic balancing devices are capable of reducing vibrations in rotary systems in a superresonance velocity zone. However, the effectiveness of automatic balancing devices is related to the necessity of accelerating compensating masses. To ensure the acceleration of compensating masses from standstill to the operating speed of the rotor, they need to be provided some initial velocity. The value of this velocity is influenced by the parameters of the elastic suspension of the rotor, the geometrical parameters of the automatic balancer, the coefficient of rolling friction between the housing and the compensating mass, etc. The work is devoted to the study of a horizontal rotor model with an automatic balancer with one compensating mass, in particular the issue on the influence of the coefficient of viscous friction on the value of the area of attraction of the auto-balancing mode.
Vibration of circumferentially stepped-thickness piezoelectric cylindrical shells
Authors: Meshkinzar Ata , Al-Jumaily Ahmed M
Published: June 2019

In this work, thickness variations are introduced around the circumference of a piezoelectric cylindrical shell. The aim is to investigate the vibration characteristics of the shells and the effect of these step-thickness variations on the mode shape of vibration. These thickness variations require stress distribution analysis as well to avoid failure of the cylindrical shell. To this aim, two configurations of stepped-thickness shells with two and three circumferential thickness variations are investigated using FEA software, ANSYS. The results show that these steps assist in localizing vibration in the thin sections and excite mode shapes having the same circumferential wave number as the number of thickness variations. This can be a suitable approach to control and forcibly excite certain vibration mode shapes, which might be required for some applications.
A comparative study on domestic and foreign equity funds in Indonesia
Authors: Suartawan I Gst Ngr Putu Adi , Artini Luh Gede Sri
Published: June 2019

The aim of this study is to analyze and compare the performance between domestic and foreign equity funds in Indonesia seen from the Treynor index, market timing, and stock selection ability. The population of this study is all equity funds registered in OJK (Financial Services Authority) in Indonesia, with a sample of 38 domestic equity funds and 25 foreign equity funds during the 2016-2018 period. The samples were collected by using a nonprobability sampling method with a purposive sampling technique. Data were analyzed using the Mann-Whitney U test. The results of this study show that the performance of foreign equity funds is better than the domestic equity funds seen from the Treynor index. The market timing ability of foreign equity funds is better than domestic equity funds. The stock selection ability of domestic equity funds is better than foreign equity funds. The practical implication of this study for investors and capital market players is to provide empirical evidence that there is a significant difference between the domestic and foreign equity funds performance in Indonesia, that can be considered in investment strategies. For investment companies that manage equity funds can be a reference to performance improvement, especially for negative performance.
The development of the system of material stimulation of civil servants
Authors: Maslennikova E. V. , Tatarinova L N
Published: June 2019

The article discusses the processes of institutional change in public service in a changing external environment, focuses on the problems of unbalancing the status of civil servants, substantiates the direction of development of the system of material incentives in the logic of performance management.
Evolution of public administration of book publishing in Russia (the middle of the XVI century - 1980s)
Authors: Zalevskaya D. G. , Yakovlev A Y
Published: June 2019

In this article author examines the history of public administration of book publishing since the birth of mass printing in the middle of the XVI century to the stagnant crisis of 1980s. During this period of time the national book publishing has changed in the legal ﬁeld, in copyright and censorship of the press, and in the structure of management, in establishment and functioning of supervisory authorities. In the 1980-s public administration of book publishing was an eﬀective centralized system of regulating the book publishing and book distribution throughout the country as a whole. But the stagnant crisis of 1980-s, which took place in many sectors of the Soviet economy, demanded reform and change.
Combined GLP-1, Oxyntomodulin, and Peptide YY Improves Body Weight and Glycemia in Obesity and Prediabetes/Type 2 Diabetes: A Randomized, Single-Blinded, Placebo-Controlled Study
Authors: Behary Preeshila , Tharakan George , Alexiadou Kleopatra , Johnson Nicholas , Wewer Albrechtsen Nicolai J. , Kenkre Julia , Cuenco Joyceline , Hope David , Anyiam Oluwaseun , Choudhury Sirazum , Alessimii Haya , Poddar Ankur , Minnion James , Doyle Chedie , Frost Gary , Le Roux Carel , Purkayastha Sanjay , Moorthy Krishna , Dhillo Waljit , Holst Jens J. , Ahmed Ahmed R. , Prevost A. Toby , Bloom Stephen R. , Tan Tricia M.
Published: June 2019

OBJECTIVE

Roux-en-Y gastric bypass (RYGB) augments postprandial secretion of glucagon-like peptide 1 (GLP-1), oxyntomodulin (OXM), and peptide YY (PYY). Subcutaneous infusion of these hormones (“GOP”), mimicking postprandial levels, reduces energy intake. Our objective was to study the effects of GOP on glycemia and body weight when given for 4 weeks to patients with diabetes and obesity.

RESEARCH DESIGN AND METHODS

In this single-blinded mechanistic study, obese patients with prediabetes/diabetes were randomized to GOP (n = 15) or saline (n = 11) infusion for 4 weeks. We also studied 21 patients who had undergone RYGB and 22 patients who followed a very low-calorie diet (VLCD) as unblinded comparators. Outcomes measured were 1) body weight, 2) fructosamine levels, 3) glucose and insulin during a mixed meal test (MMT), 4) energy expenditure (EE), 5) energy intake (EI), and 6) mean glucose and measures of glucose variability during continuous glucose monitoring.

RESULTS

GOP infusion was well tolerated over the 4-week period. There was a greater weight loss (P = 0.025) with GOP (mean change −4.4 [95% CI −5.3, −3.5] kg) versus saline (−2.5 [−4.1, −0.9] kg). GOP led to a greater improvement (P = 0.0026) in fructosamine (−44.1 [−62.7, −25.5] µmol/L) versus saline (−11.7 [−18.9, −4.5] µmol/L). Despite a smaller weight loss compared with RYGB and VLCD, GOP led to superior glucose tolerance after a mixed-meal stimulus and reduced glycemic variability compared with RYGB and VLCD.

CONCLUSIONS

GOP infusion improves glycemia and reduces body weight. It achieves superior glucose tolerance and reduced glucose variability compared with RYGB and VLCD. GOP is a viable alternative for the treatment of diabetes with favorable effects on body weight.
Association of Habitual Daily Physical Activity With Glucose Tolerance and β-Cell Function in Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes From the Restoring Insulin Secretion (RISE) Study
Authors: Temple Karla A. , Tjaden Ashley H. , Atkinson Karen M. , Barengolts Elena , Hannon Tamara S. , Mather Kieren J. , Utzschneider Kristina M. , Edelstein Sharon L. , Ehrmann David A. , Mokhlesi Babak ,   RISE Consortium Investigators, Zeitler Philip S. , Williams Jayne , Cree-Green Melanie , Reyes Yesenia Garcia , Vissat Krista , Ehrmann David A. , Temple Karla A. , Rue Abby , Barengolts Elena , Mokhlesi Babak , Van Cauter Eve , Sam Susan , Miller M. Annette , Kahn Steven E. , Atkinson Karen M. , Palmer Jerry P. , Utzschneider Kristina M. , Gebremedhin Tsige , Kernan-Schloss Abigail , Kozedub Alexandra , Montgomery Brenda K. , Morse Emily J. , Mather Kieren J. , Garrett Tammy , Hannon Tamara S. , Lteif Amale , Patel Aniket , Chisholm Robin , Moore Karen , Pirics Vivian , Pratt Linda , Nadeau Kristen J. , Gross Susan , Savage Peter J. , Leschek Ellen W. , Arslanian Silva A. , Brown Kathleen , Guerra Nancy , Porter Kristin , Caprio Sonia , Savoye Mary , Pierpont Bridget , Buchanan Thomas A. , Xiang Anny H. , Trigo Enrique , Beale Elizabeth , Hendee Fadi N. , Katkhouda Namir , Nayak Krishan , Martinez Mayra , Montgomery Cortney , Wang Xinhui , Edelstein Sharon L. , Lachin John M. , Tjaden Ashley H. , Marcovina Santica , Harting Jessica , Albers John , Hill Dave
Published: June 2019

OBJECTIVE

We examined the relationship between habitual daily physical activity and measures of glucose tolerance, insulin sensitivity, and β-cell responses in adults with impaired glucose tolerance (IGT) or drug-naive, recently diagnosed type 2 diabetes.

RESEARCH DESIGN AND METHODS

Participants included 230 adults (mean ± SD age 54.5 ± 8.5 years, BMI 35 ± 5.5 kg/m2; 42.6% women) who underwent a 3-h oral glucose tolerance test (OGTT) and hyperglycemic clamp. Wrist accelerometers worn for 7 consecutive days measured total physical activity counts (TAC) (daily mean 233,460 [∼50th percentile for age]). We evaluated whether TAC was associated with fasting plasma glucose, OGTT 2-h plasma glucose or glucose incremental area under the curve (G-iAUC), hyperglycemic clamp measures of insulin sensitivity (steady-state glucose infusion rate/insulin [M/I]) and β-cell responses (acute C-peptide response to glucose, steady-state C-peptide, and maximal β-cell response), and OGTT C-peptide index (ΔC-peptide0–30/Δglucose0–30).

RESULTS

After adjustments for confounders, there was no association of TAC with fasting plasma glucose, 2-h glucose, or G-iAUC. Higher TAC was associated with higher insulin sensitivity (M/I). After adjusting for M/I, higher TAC was not associated with measures of β-cell response.

CONCLUSIONS

In adults with IGT or drug-naive, recently diagnosed type 2 diabetes, higher levels of habitual physical activity are associated with higher insulin sensitivity. Further studies are needed to understand why higher levels of physical activity are not associated with better β-cell response.
Can startle response magnitudes be used as a tool to predict sportive capacities? A comparative study between healthy young adults and athletes.
Authors: Hormigo Sebastian , Moreno Carlos
Published: June 2019

The acoustic startle reflex (ASR) is an intense reaction that involves the contraction of muscle groups in response to an unexpected stimulus. We proposed that an ASR measurement may be used to select physical characteristics among healthy people, including athletes. To find the relationship between the ASR and physical conditioning level, we designed a study to perform ASR measurements, anthropometric measurements, neuromuscular conjugation exercises, strength test, and flexibility test. We studied young adults into 4 groups: male-control, male-athlete, female-control, and female-athlete. Our results showed how the startle amplitude was decreased in athletes compared with controls. In most of the anthropometric parameters, there were differences attending to gender in control groups, but these differences diminished in athletes. In addition, some fitness values were correlated with the latency of the muscle response and with the prepulse inhibition. This study demonstrates that regular practice of a sport, aside from causing changes in common fitness variables, also promotes changes in ASR parameters. In some way, the intense body training stimulates the brain reorganization to enhance some responses related to adapt the ASR. With this study, we are opening a field for those interested in finding out new instruments to discriminate athletes.
Problems and prospects of development of tourism infrastructure in the Republic of Kazakhstan
Authors: Tursynova Тangal , Berdenov Zharas , Faley Roza
Published: June 2019

Analyzed the state of tourism infrastructure in the Republic of Kazakhstan. Displaying poor development of the basic elements of tourism infrastructure: transport, accommodation, catering, training. Thеre were formulated the ways of solving the existing problems of development of tourism infrastructure, particularly in the information and organizational support.
Evaluasi Kematangan Pascapanen Pisang Barangan untuk Menentukan Waktu Panen Terbaik Berdasarkan Akumulasi Satuan Panas
Authors: Widodo Winarso Drajad , Suketi Ketty , Rahardjo Rizky
Published: June 2019

Buah pisang termasuk buah klimakterik dengan umur simpan pendek. Penanganan pascapanen buah pisang bertujuan untuk mempertahankan kualitas dan umur simpan buah. Tingkat kematangan buah ketika dipanen dapat mempengaruhi kualitas buah. Penelitian ini bertujuan untuk mempelajari pengaruh perbedaan umur petik terhadap kriteria kematangan pascapanen dan menentukan umur petik terbaik pisang Barangan berdasarkan akumulasi satuan panas. Percobaan dilaksanakan di PT. Perkebunan Nusantara VIII Kebun Parakan Salak, Sukabumi, Jawa Barat dan Laboratorium Pascapanen, Departemen Agronomi dan Hortikultura, Fakultas Pertanian, Institut Pertanian Bogor. Percobaan menggunakan rancangan kelompok lengkap teracak dengan 5 perlakuan umur petik: 68, 73, 78, 83, dan 88 hari setelah antesis (HSA). Setiap perlakuan diterapkan pada 5 tandan sebagai ulangan. Buah pisang Barangan dapat dipanen pada umur petik 78 HSA dengan akumulasi satuan panas sebesar 1 200-1 250 °C hari dan umur simpan mencapai 13-14 hari setelah panen (HSP). Buah pisang Barangan dengan umur petik lebih tua lebih cepat mencapai kematangan pascapanen dibandingkan buah dengan umur petik muda. Perlakuan umur petik 68-88 HSA mempengaruhi bobot buah, susut bobot, kekerasan kulit buah, kandungan vitamin C, padatan terlarut total (PTT), asam terlarut total (ATT), dan rasio PTT/ATT, namun tidak mempengaruhi kekerasan daging buah dan edible part.
Budidaya Bunga Potong Tulip (Tulipa gesneriana L.) di Nieuwe Wetering, Belanda Selatan
Authors: Lamawati Shelvy , Kartika Juang Gema
Published: June 2019

Bunga potong merupakan komoditas dengan jumlah ekspor tertinggi di Belanda yang mencapai nilai ekspor sebesar 9.1 juta euro. Penelitian dilaksanakan di Nieuwe Wetering, Belanda Selatan dari 19 Februari sampai 19 Mei 2018. Penelitian ini bertujuan untuk meningkatkan keterampilan dan pengetahuan dalam aspek budidaya bunga potong tulip dan aspek khusus berupa pertumbuhan dan produksi tulip. Penelitian dilaksanakan dengan mengikuti semua kegiatan budidaya tulip. Persentase panen bunga tulip yaitu sebesar ≥ 80% dari total populasi. Penurunan produksi tulip pada tahun 2018 terjadi karena ukuran umbi yang lebih besar, dan jumlah varietas yang ditanam lebih sedikit. Tulip varietas Versaci memiliki harga jual yang lebih tinggi karena morfologinya yang unik dengan warna tepalnya merah dan terdapat serabut di bagian ujung tepal.
Pemberian Dosis Pupuk Kandang dan Interval Panen terhadap Produksi Jawer Kotok (Coleus atropurpureus L. Benth)
Authors: Ayunina Krisetya , Aziz Sandra Arifin
Published: June 2019

Jawer Kotok merupakan tanaman obat yang berasal dari Indonesia. Tanaman ini memiliki berbagai khasiat untuk kesehatan, tetapi belum banyak diketahui dan dibudidayakan sebagai tanaman obat. Produksi Jawer Kotok yang optimum memerlukan pertimbangan dari segi produktivitas tanaman serta bahan aktif yang terkandung di dalamnya. Budidaya tanaman obat umumnya dilakukan secara organik untuk menghindari pengaruh bahan kimia pada senyawa bioaktif dalam tanaman. Penelitian ini dilakukan untuk mengetahui dosis pupuk kandang dan interval panen yang dapat menunjang produksi Jawer Kotok sebagai tanaman obat. Penelitian dilaksanakan di Kebun Percobaan Cikabayan, Bogor, Jawa Barat, Indonesia pada bulan Januari hingga Juli 2018. Rancangan lingkungan yang digunakan adalah Rancangan Kelompok Lengkap Teracak dengan tiga ulangan. Hasil penelitian menunjukkan bahwa dosis pupuk signifikan meningkatkan bobot basah batang total serta variabel pertumbuhan berupa pertambahan tinggi tanaman, lebar tajuk dan jumlah cabang. Interval panen yang sering signifikan menurunkan  bobot basah daun total dan variabel pertumbuhan berupa jumlah daun, pertambahan tinggi tanaman, lebar tajuk, jumlah cabang, kadar air, dan persentase daun batang. Interval panen signifikan menurunkan kadar klorofil a, karoten, dan total klorofil daun. Terdapat interaksi antara dosis pupuk dan interval panen pada parameter pertambahan tinggi tanaman pada 10 dan 26 MST.
Синтез, противосудорожная и ноотропная активность производных 4-фенилпирролидона
Authors: Жмуренко Людмила Александровна , Литвинова Светлана Александровна , Мокров Григорий Владимирович , Ковалев Иван Георгиевич , Воронина Татьяна Александровна , Неробкова Любовь Николаевна , Гудашева Татьяна Александровна
Published: June 2019

Представлен дизайн новых производных 4-фенилпирролидона на базе структур рацетамов, сочетающих ноотропное и противосудорожное действие. Осуществлен синтез соединений предложенной группы с использованием 4-фенилпирролидона и ароматических аминов. Изучена противосудорожная активность новых веществ и проведен анализ связи структура — действие. Наиболее выраженную активность проявляет 2,6-диметиланилид (2-оксо-4-фенилпирролидин-1-ил)уксусной кислоты в дозах 2,5 – 5,0 мг/кг, который во всех тестах превосходит препарат сравнения левитирацетам в дозах 2,5 – 600 мг/кг и обладает отчетливой ноотропной активностью, сопоставимой с активностью эталонного ноотропного препарата пирацетама в дозе 400 мг/кг.
Влияние флавоноидов Lychnis chalcedonica L. на развитие перевиваемых опухолей у мышей и эффективность цитостатической терапии
Authors: Амосова Евдокия Наумовна , Зуева Елена Петровна , Лопатина Ксения Александровна , Сафонова Елена Андреевна , Разина Татьяна Георгиевна , Рыбалкина Ольга Юрьевна , Зибарева Лариса Николаевна
Published: June 2019

Из интродуцированного в Сибирском ботаническом саду ТГУ Lychnis chalcedonica L. получен комплекс биологически активных веществ. Анализ с использованием метода ВЭЖХ свидетельствует о том, что выделенные вещества представляют собой комплекс флавоноидов с временами удерживания 10,40; 12,45; 13,29 и 15,47 мин. Мажорным компонентом флавоноидного комплекса является виценин, пик с tr = 13,29 мин, площадь которого составила 87,4 %. Изучение комплекса флавоноидов Lychnis chalcedonica L. проведено на 3 моделях перевиваемых опухолей: карцинома легких Льюис (LLC), меланома В-16 (В-16), рак легкого РЛ-67 (РЛ-67). Результаты экспериментов на мышах линии C57Bl/6 показали, что комплекс флавоноидов Lychnis chalcedonica ингибирует развитие меланомы В-16, а при сочетанном применении флавоноидов лихниса с циклофосфамидом увеличивает антибластомную активность цитостатика у животных с В-16, РЛ-67 и LLC.
Применение метода ближней инфракрасной спектроскопии в анализе субстанции кемантана
Authors: Толкачева А. В. , Балыклова К. С. , Грушевская Л. Н. , Авдюнина Н. И. , Пятин Б. М. , Прокофьева В. И. , Чернова С. В. , Гаевая Людмила Михайловна , Сергеева М. С.
Published: June 2019

Ближняя ИК-спектроскопия является перспективным методом анализа в фармации. Показана возможность применения его как экспресс-метода для подтверждения подлинности и анализа чистоты субстанции кемантана (5-гидроксиадамантан-2-она).