bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical and laboratory markers of severity of the new coronavirus infection (COVID - 19)
Authors:   Chita State Medical Academy, Ma-Van-de V.D. , Zaitsev D.N. ,   Chita State Medical Academy, Filev A.P. ,   Chita State Medical Academy, Mukha N.V. ,   Chita State Medical Academy, Ratsina E.V. ,   Chita State Medical Academy, Vasilenko P.V. ,   Chita State Medical Academy, Vasilenko E.A. ,   Chita State Medical Academy, Fetisova N.V. ,   Chita State Medical Academy
Published: July 2022

The aim of the research. To study clinical and laboratory features of the new coronavirus infection (COVID-19) in order to develop a model that would allow, taking the publicly available research methods into account, to carry out early diagnosis of severe community-acquired pneumonia against the background of the new coronavirus infection. Material and methods. A total of 82 COVID-19 patients who complied with inclusion and exclusion criteria were enrolled. Depending on the clinical severity, three study groups were formed: group 1 included 13 patients with uncomplicated COVID-19, group 2 consisted of 39 patients with non-severe forms of pneumonia that developed against COVID-19 and group 3 was comprised of 30 patients with COVID-19 complicated by severe pneumonia. The groups were comparable in age and gender. All patients underwent general clinical examination, laboratory tests, including general and biochemical blood analysis, as well as chest computed tomography. Results. The clinical picture in COVID-19 patients differed depending on the disease severity. Coughing and shortness of breath were more often observed in patients with severe pneumonia; sore throat, on the contrary, was more often noted in patients with uncomplicated COVID-19. On admission to the inpatient facility, patients with severe pneumonia had higher body temperature and respiratory rate, with simultaneous decrease in blood oxygen saturation. One half of the patients with severe pneumonia had hypertensive disease in medical history, and one third had ischaemic heart disease. As a rule, uncomplicated COVID-19 patients did not have ischaemic heart disease. It was found through laboratory analysis of blood that groups of patients significantly differed in the levels of neutrophils, lymphocytes, monocytes, basophils and eosinophils. Conclusion. The use of such clinical and laboratory data as acute respiratory failure, fever, the levels of neutrophils, monocytes, lymphocytes, eosinophils and basophils makes it possible to identify patients with more severe pneumonia against the background of COVID-19 even before chest computed tomography.
Hipátia
Authors: Shintaku Milton , Braga Tiago Emmanuel Nunes , Oliveira Alexadre de Faria
Published: July 2022

Objetivo: o presente estudo tem por objetivo apresentar o Hipátia como solução para integrar sistemas arquivísticos no processo de preservação  Métodos: Como estudo com aspectos exploratórios, faz uso da técnica 5W2H para descrever um cenário Resultados: o Hipátia, software livre desenvolvido pelo Ibict, integra sistemas de tramitação de documentos arquivísticos com repositórios confiáveis, seguindo as orientações do modelo OAIS, mantendo a cadeia de custódia. Conclusão: o Hipátia se apresenta como solução viável para órgãos e instituições que utilizam o Archivematica como RDC-Arq, integrando-o ao sistema produtor e de trâmite de documentos digitais.
Preservação digital distribuída para teses e dissertações
Authors: Gonçalves Pâmella Benevides , Marques Clediane de Araújo Guedes , Bastos Flávia Maria , Ferraro Fabiana Colares , Loureiro Ana Cristina Figueiredo
Published: July 2022

Introdução: As teses e dissertações digitais (ETDs), são documentos importantes e necessários para a conclusão dos cursos de pós-graduação, desse modo, é importante a sua preservação a longo prazo. Devido à especificidade de seus metadados foi elaborada a proposta de preservação digital, para as teses e dissertações da Universidade Estadual Paulista (Unesp) e da Universidade Federal do Rio Grande do Norte (UFRN), com base no modelo de Preservação Digital Distribuída (PDD) junto à Rede Cariniana do Instituto Brasileiro de Ciência e Tecnologia (IBICT). Objetivo: Estabelecer uma proposta de preservação digital distribuída para as (ETDs) dessas universidades, integrada a seus repositórios institucionais e identificar os requisitos para compor um ciclo de vida para (ETDs) que incorpore o processo de preservação digital. Metodologia: Trata-se de um levantamento bibliográfico na área da Ciência da Informação, que considera definições, estratégias e metodologias aplicáveis ao ciclo de vida da preservação digital de ETDs. Resultados: A Unesp e a UFRN reconheceram na literatura os requisitos e etapas para compor o processo do ciclo de vida de preservação digital, os quais contemplam todas as etapas, desde sua criação, uso, reuso, migração e/ou emulação e armazenamento. E como parte do processo elaboraram uma “minuta de um modelo da política de preservação digital de coleções em repositórios institucionais e bibliotecas digitais”. Conclusão: Constatou que a preservação das ETDs deve ser constante, contínua e atualizada. As instituições prosseguem com os estudos, com o intuito de finalizar o plano de ação e implantação da referida proposta de preservação digital distribuída.
Agnaldo dos Santos e o museu de arte negra de Abdias do Nascimento
Authors: Corrêa Gabriela Caspary
Published: July 2022

A proposta deste trabalho é colaborar com o aprofundamento da recepção crítica do escultor Agnaldo dos Santos (1926-1962), estabelecendo contato entre sua produção e a formação do Museu de Arte Negra (MAN), idealizado por Abdias do Nascimento (1914-2011). A constituição da coleção do MAN caracterizou-se pela tentativa de reunir obras que tivessem como premissa padrões estéticos de matriz africana. O propósito é observar a diversidade de intenções no âmbito das escolhas estéticas de Agnaldo dos Santos em sua prática artística e a formação da coleção do MAN.
Richard Speare
Authors: Wilkes Robert John
Published: July 2022

This article is the first to examine a little-known British artist, Richard Speare (1785–1815), who visited Brazil in 1808–9 and exhibited three watercolours of Brazilian subjects at the prestigious Royal Academy of Arts in London. It presents new biographical information about Speare, including his involvement with the mission to relocate the Braganza royal family from Lisbon to Rio de Janeiro. The article also analyses two engravings reproducing Speare’s drawings of Rio de Janeiro, which were published in a British magazine during the artist’s lifetime.
Factors Affecting the Application of Human Resources Accounting in Higher Education Institutions: A Field Study at Private Yemeni Universities
Authors: Al-Sorihi Sultan Ali , Abofarea Fatehia Ghilan
Published: July 2022

This research aimed to examine the most important factors affecting the application of human resources accounting in private Yemeni universities. To achieve this objective, one hundred questionnaires were distributed to the staff of high level management, human resources management, and finance management in private Yemeni universities in the academic year 2015-2016. 74 questionnaires were returned, and all were appropriate for statistical analysis. The multiple regression analysis technique was used to test the research hypotheses. . The major findings of this research revealed that the variable of assets accounting acknowledgment criteria had a significant positive effect on AHRA while the variables of administration awareness of the importance of human resources accounting and the application difficulties had no effect.  Therefore, it is recommended that government concerned bodies should take into consideration that the establishments believe in their right to obtain and possess qualified, trained and experienced human resources in return for what is paid to them. This is considered an indicator of economic ownership of human resources, rather than legal ownership. It is also an indication of the criteria of assets acknowledgment, and the culture of disclosure expansion. This would require the development of regulations in the law (99) for the year 1999 concerning accounting and auditing profession to facilitate the use of AHRA in order to take effective and more efficient decisions so as to improve the performance of enterprises and determine the overall benefits to achieve economic stability and social justice in Yemen.

Keywords: Human resources accounting, Influencing factors, Yemeni private universities.
Present Situation of Commitment to Internal and External Social Responsibility of Companies and its Impact on Organizational Performance: A Field Study in the Telecommunication Companies – Yemen
Authors: الجناعـي نوري عبـدالودود , أبوهـادي عبدالله جابـر حسـن
Published: July 2022

The study aimed to explore the present situation of the commitment to internal and external social responsibility of companies and its impact on organizational performance at the telecommunication companies in the Republic of Yemen. To achieve the objective of the study, the research used a descriptive and analytical method, using a questionnaire for data collection. The results revealed that there was a significant effect of internal social responsibility on the organizational performance of telecommunication companies in the Republic of Yemen at the level of less than (0.05). The source of the positive impact of internal social responsibility was mainly on the ethical, economic, legal and human dimensions. As for the external social responsibility, the impact was mainly on the ethical, legal, human, and economic dimensions.It was found that the highest level of commitment of external social responsibility was mainly in the legal, moral and economic dimensions, respectively, whereas the human dimension received a medium score. As for the internal social responsibility, the commitment was mainly in the legal, economic and moral dimensions, respectively, whereas the human dimension received a medium score. Aslo, the level of organizational performance in telecommunication companies in the Republic of Yemen was medium.

Keywords: Social responsibility, Organizational performance, Telecommunication companies in Yemen.
Impact of Applying Internal Marketing on Workers’ Organizational Commitment at MTN Yemen
Authors: اسكندر رجاء غالب , زهاري عمار ثابت
Published: July 2022

This study aimed to investigate the impact of internal marketing (all its dimensions of training, empowerment, motivation, teamwork, internal communication, administrative support and marketing information) on the organizational commitment of workers at MTN Yemen. The focus was on these types of organizational commitment: emotional, normative and continuity. The study adopted the descriptive method, and used a questionnaire to collect data. The population consisted of 250 employees who represent all administrative staff in the middle and executive management levels in the main office of the company in the capital city of Sana’a. A simple random sample of (152) participants was selected. 152 questionnaires were distributed but only 107 were returned. The study results revealed that there is a positive effect of applying internal marketing with all its dimensions on the organizational commitment of the company workers. The level of applying the internal marketing practice by the administrative leaders of the company is high, and the level of the organizational commitment of the employees of the company and its various types is also high. The study recommended that more attention should be given to the dimensions of internal marketing by the administrative leaders in the company. They are also recommended to implement policies and programs more effectively, as this would lead to more improvement in the organizational commitment by the employees. Keywords: Internal marketing, Organizational commitment, MTN Yemen.
Meanings and Implications of Civil State from an Islamic Perspective
Authors: الشيبة فكري منصور محمد
Published: July 2022

This study aimed to assess the term ‘civil state‘ by considering its origin, concept, as well as its most important principles. The focus was also to see the term’s consistency or inconsistency with the religion of Islam, or «whether the state in Islam is civil or religious». The study used the inductive descriptive method through tracking some Islamic evidence and contemporary jurisprudence opinions in this regard. The study pointed out that Islam started the notion of civil state long time ago before the Western civilization by calling for most of the essence of such principles called for by the West , although sometimes these principles are loosely used by the West. Also, sometimes western principles are not practiced in reality. However, most of them do not contradict the purposes of Islamic law if not called for by the Islam itself. In addition, Islam does not stop Muslims from benefiting from the civilization and cultural experiences of others, as long as that is in compliance with Islamic laws, and is intended to achieve the interests and progress of society. It is also possible to apply such experiences in our Islamic countries under the Islamic laws instead of indulging in a vicious circle of different ideological and sectarian conflicts that imposed heavy losses to the nation. The study concluded that there is no religious state «theocracy» of the Western meaning in Islam. The concept of ‘state’ in Islam is civil in terms of authority, religious in terms of legislation; or it is civil with religious reference. The study also indicated some obstacles and difficulties that hinder the application of such systems in our Arab and Islamic countries. Keywords: Civil state, Civil state in Islam, Islam’s view of civil state.
Children's Lyric Poetry: An Analysis of Child and the Sea by Salim Abdulqader
Authors: Abu Taleb Ibrahim Mohammed
Published: July 2022

This study aimed to identify lyrical poetry directed to children, specifying its concept, types, and characteristics. To achieve this objective, a critical analysis of a children lyrical poem written by Salim Abdulqader was conducted. The study followed the descriptive method which is based on analysis and deduction of lyrical poems addressed to children. Major findings revealed that successful child lyrical poetry is characterized by a childlike spirit which is concerned with the child's issues, worlds, and needs without intercalating the worlds of adults and their topics; it also includes some educational aspects without resorting to direct guidance. Moreover, in his song Child and the Sea, Salim Abdulqader was able to provide a successful sample of poetic discourse directed to children according to its balanced characteristics which are required in the structure of a poetic text. Such poetry meets children's needs and achieves its aesthetic, knowledge and education objectives. It is written in a language that develops children's linguistic and cognitive lexicon and provides them with many educational values which are part of pure Islamic teachings. 

Keywords: children's poetry, Child and the Sea, Salim Abdulqader.
University Education Role in Empowering Saudi Women in Light of Development Strategy 2030 from the Students' Perspective at Prince Sattam Bin Abdulaziz University
Authors: Farag Dr. Alyaa Omar Ibrahim , Sharabi Dr. Wedad Abdullah
Published: July 2022

This study aimed to identify the role of university education in empowering Saudi women in the light of the 2030 Development Strategy, and to identify the effect of some variables (study level, track, and university branch) on the role of University education from the perspective of female students. The descriptive method was used and a questionnaire, consisting of (47) items distributed over five dimensions, was designed for collecting data.  A sample of (600) female students was randomly selected from Prince Sattam Bin Abdulaziz University. The study results revealed that University education has a role in achieving the 2030 Development Strategy regarding the social and economic empowerment of Saudi women. There were no differences in the participants' responses due to the variable of the study level. The results also showed that there were no differences in the students' perspective according to the track variable in all types of empowerment except for the institutional empowerment in favor of the Arts Track. The results also showed that there were no differences between the students' views according to branches variable in the branches (Al-Kharj, Al-Sulayyil and Wadi Al-Dawasir), while differences appeared in two branches (Al-Dalam and Al-Huta). The study stressed the importance of the role of university education in achieving the 2030 Development Strategy for empowering Saudi women, and raising students’ awareness about the importance of participation in developmental, cultural, economic and social activities.

Keywords: 2030 Development Strategy, women's social empowerment, women's economic empowerment, women's empowerment, Prince Sattam Bin Abdulaziz University.
The Impact of Administrative Empowerment on the Achievement of Sustainable Competitive Advantage: A Field Study at Pharmaceutical Manufacturers in Yemen
Authors: Abdullatif Musleh Mohammed Ayedh  , Najeeb Mohammed Yahya Al-Beshari
Published: July 2022

This study aimed at measuring the impact of administrative empowerment on achieving sustainable competitive advantage at Yemeni pharmaceutical manufacturers. It also aimed to identify the extent to which sustainable competitive advantage is achieved and the level of administrative empowerment practice in these companies.  To achieve the objectives of the study, the analytical descriptive method was adopted and a questionnaire was developed to collect data from the total population of (1116) individuals at the Yemeni pharmaceutical manufacturing companies. The sample (280) was selected by means of the stratified proportional random sampling method and 245 questionnaires were valid for analysis. Data were processed and analyzed using SPSS.  Findings of the study revealed that the targeted companies have shown paramount interest towards administrative empowerment practices and the achievement of sustainable competitive advantage. Findings also showed that administrative empowerment had an impact on achieving sustainable competitive advantage in the companies, and that the dimension of sharing information had the highest impact on the achievement of sustainable competitive advantage while the dimension of influence had the lowest impact.  The study recommends the reinforcement of enhancing the practice of administrative empowerment in the companies targeted in this study.
The Effect of Childcare Teachers' Job Stress and Self-Differentiation on Depression
Authors:   The Association of Korea Counseling Psychology Education Welfare, PARK Sun-Min , KIM Yu-Mi
Published: July 2022

In this study, to examine the effect of childcare teachers' job stress on depression. For thispurpose, a survey was conducted on 253 childcare teachers working at daycare centers locatedin Seoul. The collected data were analyzed through SPSS 23.0. The main results of this studyare as follows. First, the job stress of childcare teachers was slightly lower level than normal,self-differentiation was at a level above average, and depression was at a lower level thannormal. Second, there were negative correlations between job stress and self-differentiation,self-differentiation and depression, and positive correlations between job stress and depressionof childcare teachers. Third, the general background, job stress, and self-differentiation ofchildcare teachers had a significant effect on depression. Especially, self-differentiation had asignificant effect on depression when the overall background and job stress of childcare teacherswere controlled. These results suggests that in order to reduce the depression of childcareteachers, it is necessary to take measures to reduce job stress along with counseling andeducational support that can increase the level of self-differentiation of childcare teachers.
Psychological Characteristics of College Students Maintaining Non-Suicidal Self-Injury With the Rorschach
Authors:   The Association of Korea Counseling Psychology Education Welfare, KIM Jeong-Hyeon , JO Han-Ik
Published: July 2022

This study aimed to understand the psychological characteristics of college studentsmaintaining Non-Suicidal Self-Injury(NSSI). The Rorschach case illustration(Weiner, 2005) wasused, it was divided into 4 areas: cognitive characteristics, stress coping, self and interpersonalperception, and emotional characteristics. With that 8 categories and 21 subcategories werederived and psychological characteristics were synthesized and presented along with thefrequency of cases. As a result 'inaccurate perception and interpretation of a particular situation'and 'lack of expectations for positive interpersonal interactions' were presented as commonpsychological characteristics of NSSI. And 'X-%>.20, X+%<.70, XA%<.77 & WDA%<.80', 'LowPure H, COP=0 & AG=0 or 1' derived from subcategories were presented as meaningful partsof Rorschach responses.
O DIREITO DAS MULHERES NA ORDEM JURÍDICA GLOBAL DIANTE DA VIOLAÇÃO DO PRINCÍPIO DA EFICIÊNCIA DA ADMINISTRAÇÃO PÚBLICA
Authors: Silva Giovanna Matos
Published: July 2022

O presente trabalho analisa o direito da mulher especificamente no direito administrativo, sob a ótica nacional e internacional, considerando que a legislação em prol da sua dignidade humana fora conquistada em meio a uma sociedade historicamente e culturalmente patriarcal. Salienta-se a importância da ordem jurídica global em materializar esses direitos diante a ineficiência do Estado em concretizá-los, dispondo como amostra a Lei 11.340/06 - Lei Maria da Penha, em que diante da violação do princípio da eficiência da administração pública, o direito internacional provocou a intervenção no direito pátrio para que a mulher pudesse alcançar mais uma conquista. Será abordada a forma como o feminismo contribuiu e tem contribuído para a participação da mulher no meio social, no combate à violência doméstica e ao feminicídio, e ainda como a discriminação em razão do gênero se manifesta no contexto das mulheres negras e periféricas. Assim, para a elucidação do objetivo de compreender a relevância da ordem jurídica global diante a violação do princípio da eficiência da administração pública no que se refere aos direitos da mulher, este artigo utilizará da pesquisa bibliográfica, a partir da perspectiva já consolidada sobre o assunto, apresentando resultados qualitativos ao final.
INAFASTABILIDADE JURISDICIONAL E ATUAÇÃO CONTRAMAJORITÁRIA: CONCILIANDO AS REAÇÕES SOCIAIS E A NECESSÁRIA AUTONOMIA DO DIREITO
Authors: Albuquerque Filho Renato Correia de
Published: July 2022

O texto explora o fundamento da autonomia do direito como pilar básico para a construção de uma democracia respeitadora dos limites constitucionais. Tendo como referência a atuação contramajoritária da Jurisdição, parte-se da análise da doutrina nacional e internacional, além do destaque de casos levados à Suprema Corte brasileira e americana, com o objetivo de realizar uma análise das bases fundamentais do Estado de Direito, tendo em vista alcançar uma construção decisional fundamentada e participativa para conferir maior grau de legitimidade às cortes no tratamento de matérias controvertidas.
Recent developments in the use of activated charcoal in medicine
Authors: Hassen Jasim Hamadi , Abdulkadir Hamad Kalefa
Published: July 2022

One of the raw forms of graphite is activated charcoal which has an extensive surface area allowing for the adsorption of a wide range of chemicals. It possesses the strongest physical adsorption forces of the available materials, as well as the largest volume of adsorbing porosity. Activated charcoal acts as an adsorbent, collecting and storing substances in the gastrointestinal tract, reducing or blocking absorption in the bloodstream. The ingested toxins interact with charcoal by recycling toxins in the intestinal cavity. In cases where the drug has not been absorbed from the abdominal system, it is recirculated through the liver and intestines or by means of passive diffusion or active secretion. The article aims to review the most recent advances in the use of the activated charcoal, including the dose, how charcoal acts in the body, the mechanism of action, administration, contraindications, as well as the impact of various factors on the adsorption process. In addition, we also discussed numerous medical applications of activated charcoal.
Molecular characterization of multiple myeloma
Authors: Kiremitci Buse Zeren , Gürler Elif Serap , Kiraz Yağmur
Published: July 2022

Multiple myeloma (MM) is a hematologic malignancy that occurs when plasma cells, a type of white blood cell, grow out of control and start to overproduce antibodies that accumulates in blood and bone marrow. Despite the recent advance the survival rate for MM has not been increased significantly, which opens the need for identifying new molecular targets. This review article presents the most frequently observed gene mutations (KRAS (22.0%), NRAS (18.0%), DIS3 (9.3%), TTN (8.3%), ZNF717 (8.3%), TENT5C (7.3%), TP53 (7.3%) %), BRAF (6.3%), MUC16 (6.3%), RYR2 (5.4%), LRP1B (5.4%)) in MM patients and its rates, correlations, clinical significance, importance in the framework of MM disease and potential novel targets which are collected from the literature. The genes that are mutated in MM patients (211) taken from cBioportal data set. In conclusion, in the study conducted in MM patients, the 3 genes with the most frequent mutations were recorded as KRAS, NRAS and DIS3, respectively. In addition, in the context of our literature reviews and the data obtained, it appears that the TZNF717, TTN, MUC16, RYR2 genes need further study within the framework of MM.
A Novel Method for Lung Image Processing Using Complex Networks
Authors: Broască Laura , Trușculescu Ana Adriana , Ancușa Versavia Maria , Ciocârlie Horia , Oancea Cristian-Iulian , Stoicescu Emil-Robert , Manolescu Diana Luminița
Published: July 2022

The High-Resolution Computed Tomography (HRCT) detection and diagnosis of diffuse lung disease is primarily based on the recognition of a limited number of specific abnormal findings, pattern combinations or their distributions, as well as anamnesis and clinical information. Since texture recognition has a very high accuracy percentage if a complex network approach is used, this paper aims to implement such a technique customized for diffuse interstitial lung diseases (DILD). The proposed procedure translates HRCT lung imaging into complex networks by taking samples containing a secondary lobule, converting them into complex networks and analyzing them in 3 dimensions: emphysema, ground glass opacity and consolidation. This method was evaluated on a 60 patient lot and the results show a clear quantifiable difference between healthy and affected lungs. By deconstructing the image on three pathological axes, the method offers an objective way to quantify DILD details which, so far, have only been analyzed subjectively.
Marchenko Green's Function Retrieval in Layered Elastic Media from Two-Sided Reflection and Transmission Data
Authors: Van Der Neut Joost , Brackenhoff Joeri , Meles Giovanni , Slob Evert , Wapenaar Kees
Published: July 2022

By solving a Marchenko equation, Green's functions at an arbitrary (inner) depth level inside an unknown elastic layered medium can be retrieved from single-sided reflection data, which are to be collected at the top of the medium. So far, an exact solution could only be obtained if the medium obeys stringent monotonicity conditions and if all forward-scattered (non-converted and converted) transmissions between the acquisition level and the inner depth level are known a-priori. We introduce an alternative Marchenko equation by revising the window operators that are applied in its derivation. We also introduce an auxiliary equation for transmission data, which are to be collected at the bottom of the medium, and a coupled equation, which is based on both reflection and transmission data. We show that the joint system of the Marchenko equation, the auxiliary equation and the coupled equation can be succesfully inverted when broadband reflection and transmission data are available. This results in a novel methodology for elastodynamic Green's function retrieval from two-sided data. Apart from these data, our approach requires P- and S-wave transmission times between the inner depth level and the top of the medium, as well as two angle-dependent amplitude scaling factors, which can be estimated from the data by enforcing energy conservation.
STEMI Patients in the First and Second Wave of Covid-19 Pandemic in Northeast Slovenia – A Retrospective, Single Center Observational Study
Authors: Sinkovic Andreja , Krasevec Manja , Šuran David , Marinšek Martin
Published: July 2022

Covid-19 pandemic affected outcome in ST-elevation myocardial infarction (STEMI) patients in majority of countries. We aimed to assess retrospectively admissions, treatments, complications and mortality of STEMI patients in the northeast of Slovenia in the first (March-May 2020) and the second wave (October-December 2020) of Covid-19 pandemic and compare them with the data from 2019 (March-October). Comparing 2019 and both waves of Covid-19 pandemic we observed nonsignificant differences in the number of STEMI admissions, in baseline characteristics, in the use of primary percutaneous coronary intervention (PCI), either within the first 3 (40.5%* vs 30.2% vs 25%*, *p = 0.074) and 6 hours, nonsignificant differences in TIMI III flow after primary PCI and in hospital complications, except for significant increase in hospital heart failure (23.3% vs 42%, p = 0.015) and mitral regurgitation in the second wave (10% vs 26.9%, p = 0.008) of the pandemic with nonsignificant increase in hospital mortality (8.9% vs 9.4% vs 13.6%) in both waves of the pandemic. We conclude, that with increased severity of Covid-19 pandemic in the second wave there was a longer delay to primary PCI in STEMI patients, resulting in significantly increased hospital heart failure and nonsignificantly increased hospital mortality
The Effect of Size Distribution on the Geochemistry and Mineralogy of Tropical River Sediments and Its Implications regarding Chemical Weathering and Fractionation of Alkali Elements
Authors: Wu Kaikai , Liu Shengfa , Shi Xuefa , Colin Christophe , Bassinot Franck , Lou Zhanghua , Zhang Hui , Zhu Aimei , Fang Xisheng , Mohamed Che Abd. Rahim
Published: July 2022

The mineralogical and geochemical compositions of the sediments deposited by rivers have been used extensively to evaluate past chemical weathering and the physical erosion history of drainage basins at different time scales. However, the role of sediment sorting in the mineralogical and geochemical compositions of river sediment needs to be better constrained because it could significantly modify proxies used to evaluate weathering intensity in the past. In this study, major and trace element concentrations and mineralogical compositions were determined on seven different grain-size fractions of riverbed samples taken from the Pahang and Kelantan Rivers in the Malay Peninsula. The main aims are to assess chemical weathering and the fractionation of alkali elements during sediment transportation under tropical climate conditions. Fine sediments (from <2 μm to 4-8 μm) were characterized by higher concentrations of Al2O3, P2O5, V, Sc, and Cs than coarse sediments (from 8-16 μm to 32-63 μm). The presence of heavy minerals, such as zircon and monazite, was found to have critical effects on the concentration of several elements (e.g., Zr and Th), leading to extremely high elemental concentrations in the coarse-sediment fractions. Variations in elemental concentrations with particle sizes are mainly attributed to changes in the mineralogical composition during mineral sorting and weathering. In both rivers, the intensity of chemical weathering increased with decreasing grain sizes. However, the relationship between grain size and chemical weathering trends in the Pahang and Kelantan River basins was different in each case due to differences in plagioclase and K-feldspar concentrations, especially in the coarse-sediment fractions (16-32 μm and 32-63 μm). Kaolinite percentage, illite chemistry index, and illite crystallinity were directly proportional to the chemical index of alteration (CIA), suggesting that these mineralogical parameters are suitable proxies for determining chemical weathering intensity in sediments that have undergone significant changes due to mineral sorting during transportation. The comparison of Rb/K and Cs/K ratios and the CIA suggested that K and Rb mainly derive from primary minerals during the process of chemical weathering, whereas Cs is mainly present in fine weathered particles due to the reabsorption of Cs on clay minerals. Overall, our results highlight the relationship of grain size and mineral assemblages to different states of chemical weathering (and alkali fractionation) in tropical river basin sediments. These relationships need to be considered when using mineralogical and geochemical compositions to reconstruct weathering history in a “source to sink” approach.
Study on Multisize Effect of Mining Influence of Advance Speed in Steeply Inclined Extrathick Coal Seam
Authors: Jia Chong , Lai Xingping , Cui Feng , Feng Ganggui , He Shifeng , Gao Yuanjiang , Tian Mengqi
Published: July 2022

Aiming at the multisize effect of mining in steeply inclined extrathick coal seam, taking the fully mechanized top-coal caving mining in B3+6 coal seam +425 level in the south of Wudong coal mine as the background, this paper studies the mining stress evolution law under the influence of advancing speed, analyzes the mechanical characteristics of coal samples under the mining action of steeply inclined extrathick coal seam, and completes the multisize effect study of mining in steeply inclined extrathick coal seam. The results show that the stress change theory of fully mechanized top-coal caving mining in steeply inclined seam is deduced, and the loading and unloading stress of fully mechanized top-coal caving mining is positively correlated with the advancing speed of the working face. The numerical simulation experiment shows that the ideal advancing condition increases with the advancing speed of the working face, and the cyclic loading and unloading amplitude under the mining stress path increases, the cyclic times decrease, the main influence area increases, and the acting time decreases. The peak value of mining stress, the width of the plastic zone, and its elastic energy under high-speed propulsion are obviously larger. A method of mechanical behavior analysis of coal samples is proposed, which takes the mining stress path of the numerical simulation experiment as the indoor scale loading and unloading stress path of coal samples. The average compressive strength of coal samples under the mining stress path increases with the advancing speed of the working face, and the damage degree of coal samples increases with the advancing speed of different stress paths. The input strain energy of coal cyclic loading and unloading increases with the increase in the advancing speed of the stress path. The input strain energy of the coal sample has obvious linear relationship with the advancing speed of different paths. The research results can be used for reference in the study of multisize effect of mining impact of advancing speed.
Application of Remote Fetal Heart Rate Monitoring Based on Internet in Late Pregnancy During the COVID-19 Pandemic
Authors: Zhou Shuguang , Jin Qinqin , Jiang Xiya , Bingbing Wang , Yao Hui , Yang Yinting , Ying Jie , Tian Lu , Zhang Weiyu , Zhu Yuting , Chen Guo , Cao Wujun
Published: July 2022

Objective：To evaluate the consistency of pregnancy outcomes and related clinical monitoring indicators in high and low risk group under two different monitoring methods during COVID-19 pandemic.Methods：760 cases of late pregnant women admitted to our hospital from March 2020 to February 2021 were selected for this study. They were randomly divided into control group (n = 380) and observation group (n = 380). Observation group the fetus was monitored remotely at home，while the control group went to the hospital for fetal heart monitoring.To evaluate the consistency of pregnancy outcomes and related clinical monitoring indicators in different groups under two different monitoring .Results:It was found that there was no statistically significant difference between the two groups in terms of pregnancy outcome (including mode of delivery, postpartum hemorrhage, etc.) and neonatal outcome (including preterm birth rate, neonatal weight, neonatal Apgar score, etc.) (p>0.05). It should also be noted that the difference in EPDS score results between the two groups was statistically significant (p<0.05) . Meanwhile, there was a statistically significant difference in the total cost of labor and delivery between two groups (p<0.05) and total time spent on labor and delivery between the two groups(p<0.05).Conclusions:Remote Fetal Heart Rate Monitoring Based on Internet is an innovative, acceptable, and effective reduced-frequency prenatal examination model. Compared to routine prenatal examination, Remote Fetal Heart Rate Monitoring Based on Internet resulted in higher patient satisfaction and lower prenatal stress. Besides, Remote Fetal Heart Rate Monitoring Based on Internet compared with the traditional fetal heart monitoring does not affect the pregnancy outcomes of pregnant women with different risk factors, maternal accept degree is high, and to reduce the medical resources pressure. It is an effective and feasible way for self-monitoring of pregnancies in late pregnancy during the pandemic of COVID-19 and is worthy of clinical application.
Isoflavones have a potential role in off-flavour scavenging, with isoflavone synthase 2 (IFS2) as a key player in determining isoflavone accumulation in soybean seeds
Authors: Kumar Sandeep , Banerjee Sagar , Kaur Amandeep , Sasi Minnu , Kumari Sweta , Sachdev Archana , Dahuja Anil
Published: July 2022

Soybean (Glycine max (L.) Merr) is a nutrient-rich crop with limited consumer acceptability because of the presence of off-flavour. Owing to the ubiquity of isoflavones in soybean, their inherent antioxidant potential, and their inhibitory effect on lipoxygenase activity, their sensorial attribute in mitigating off-flavour is currently being envisaged. We estimated the content and composition of isoflavones in 17 soybean cultivars and established the correlation between isoflavone profile and lipid peroxidation, which was measured in terms of thiobarbituric acid (TBA) number and carbonyl value. The results showed a significant negative correlation of these parameters with the total isoflavone content and genistein: daidzein ratio. In addition, expression analysis of a key gene involved in isoflavone biosynthesis, i.e., isoflavone synthase (IFS1 and IFS2), in contrasting soybean genotypes during seed development revealed a higher expression of both isoforms in Bragg (high isoflavone) compared to PUSA 40 (low isoflavone) at different stages of seed development accompanied by more isoflavone accumulation. The cloning and in silico analysis of IFS isoforms revealed a more significant interaction with other biosynthesis enzymes by IFS2, indicating its more substantial role in isoflavone synthesis. IFS2 overexpression can thus be a valuable target to increase isoflavone biosynthesis, thereby scavenging off-flavour.
Research on the Technology of Breaking the Shannon Channel Capacity and Shannon Limit
Authors: Liang Dequn , Dou Xinyu
Published: July 2022

In this paper, firstly, the Shannon channel capacity is briefly stated, and the relationship between it and the signal uncertainty principle is analyzed in order to prepare for deriving the formula which can break through the Shannon channel capacity. Then, as practical examples of breaking the Shannon channel capacity, the time-shift non-orthogonal multicarrier modulation technology (TS-NMT) and the time frequency pulse time delay multicarrier modulation technology (TFP-TDMC) are introduced. After more than twenty years of development, this technique is proved to be a practical modulation technique for digital communication. At the end of the paper, a hypothesis about the physical nature of information is proposed.
Microbial bioremediation of feather wastes and eco-friendly production of keratinase and collagenase enzymes by Didymella keratinophila, the first-recorded fungus from Assiut, Egypt
Authors: Al-Bedak Osama Abdel-Hafeez Mohamed , Moharram Ahmed Mohamed , Hussein Nemmat Abdel-Gawad , Taha Doaa Mohamed
Published: July 2022

During a routine examination of Coelomycetes isolated from various fruit juices in Assiut Governorate, Egypt, a unique isolate was discovered and visually identified as a Didymella member. The fungus was confirmed as Didymella keratinophila based on sequencing of the internal transcribed spacer (ITS), since it had 100% identity to the type strain. This is the first time the fungus has been recorded in Egypt. The strain was able to flourish and hydrolyze native chicken feather in SmF to produce keratinase and collagenase enzymes. The keratinase enzyme performed best at pH 7.0 and 45 oC, yielding 44903 ± 1555 IU/mg keratinase activity, while collagenase enzyme be really at pH 6.0 and 8.0 at 35 oC and 60 oC, yielding 15753 ± 110 IU/mg and 16312 ± 21 IU/mg, respectively indicating two collagenases. The keratinases and collagenases produced were significantly inhibited by EDTA and the ions. Mn+ 2 had the most effective inhibitory effect on keratinases while K+ had the most potent inhibitory influence on collagenase. The current study identifies a feasible producer of keratinase and collagenase enzymes sourced from chicken feathers, providing a safe method for using these wastes to produce high-value commodities.
Distribution and ecological risk assessment of heavy metals in sediments of Dajiuhu Lake Wetland in Shennongjia, China
Authors: Wang Jiumei , Ge Jiwen , Yang Xiaojing , Cheng Dandan , Yuan Chenhao , Liu Ziwei , Yang Shiyu , Guo Yan , Gu Yansheng
Published: July 2022

The rapid development of modern industrialization led to the discharge of high number of heavy metals into wetlands, which continued to accumulate and cause pollution. Located in the Shennongjia Forest District of Hubei Province in China, Dajiuhu is one of the list of international key wetlands, which is a typical representative of the wetland ecosystem and has certain scientific research value. In this study, the surface sediments of nine sub-lakes in Dajiuhu were collected in August 2020, and the total contents of Cd, Cr, Cu, Ni, Pb and Zn in the sediments have been measured. The occurrence and speciation characteristics of heavy metals have been analyzed by an improved BCR extraction method. Potential ecological risk index, geo-accumulation index, risk assessment code and pollution factor method were used to evaluate the pollution degree and ecological risk of heavy metals. The possible sources of heavy metals were estimated based on the total contents of heavy metals. The results show that the heavy metal content in lake sediments of Dajiuhu wetland is Zn>Cr>Ni>Pb>Cu>Cd in sequence, and only the average content of Cd exceeded the standard of the national nature reserve. Although Pb did not exceed the standard value, due to the proportion of different forms caused it and Cd both brought some pollution as well as ecological risk to the lakes and wetlands. The spatial distribution of heavy metal content in the nine sub-lakes does not vary regularly. The sources of heavy metals in the lake sediments of Dajiuhu wetland among which Ni, Cr and Cu are mainly natural factors, Cd and Pb are mainly anthropogenic factors, and Zn is caused by both sources together. This study can further improve the study of heavy metal pollution in the lake wetlands and provide a relevant basis and direction for the management of heavy metal pollution in the Dajiuhu wetland.
The impact of tumor board on breast cancer care: evidence from a systematic literature review and a meta-analysis
Authors: Pilla Andrea Di , Cozzolino Maria Rosaria , Mannocci Alice , Carini Elettra , Spina Federica , Castrini Francesco , Grieco Albino , Messina Sara , Damiani Gianfranco , Specchia Maria Lucia
Published: July 2022

BackgroundBreast cancer is the most common malignancy in women, with a complex clinical path that involves several professionals. A multidisciplinary approach is therefore essential and there is a growing emphasis on its application to breast cancer care. However, the effectiveness of breast cancer multidisciplinary care and the processes that contribute to its effectiveness have not yet been firmly determined. This study aims to evaluate the impact of MTBs on breast cancer care outcomes.MethodsA systematic literature review was carried out through Scopus, Web of Science and Pubmed databases. The search was restricted to articles assessing the impact of MTB implementation on breast cancer care, written in English and Italian language, published between 1995 and 2021.The quality of the included articles was assessed using the Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies and the Quality Assessment Tool for Before-After (Pre-Post) Studies With No Control Group from National Heart, Lung and Blood Institute Study Quality Assessment Tools. To combine not homogeneous results, when appropriate, meta-analysis was performed.ResultsFourteen studies, published between 2006 and 2021, were included in the review. From the quality assessment, seven studies were found to be of FAIR and seven of GOOD quality. The most analysed outcomes were: diagnosis, therapy and survival. Four out of four studies showed that with the implementation of the MTB there was a change in diagnosis, and seven out of seven studies reported changes in the treatment plan after MTB implementation. In terms of survival, results were not unanimous. A pooled analysis of three studies reporting results on the outcome “mortality” showed, in the fixed-effects model (p=0.43), a statistically significant 14% reduction of mortality relative risk for patients enrolled versus not enrolled in MTBs (pooled HR = 0.86; 95%CI: 0.81- 0.97). ConclusionsThis study shows that the implementation of the MTBs is a valuable approach to deliver appropriate and effective care to patients affected by breast cancer and to improve their outcomes. Further studies are needed to enrich the evidences available to date concerning especially the outcomes less investigated, but important to improve clinical care and care processes.