bluuebunny/crossref_metadata_2025 huggingface dataset:
Variabilité Spatio-Temporelle de la Pluviométrie dans les Zones Soudaniennes, Soudano-Sahélienne et Sahélenne du Burkina Faso
Authors: Karambiri Bienvenue Lawankiléa Chantal Noumpoa , Gansaonre Raogo Noël
Published: March 2023

L’évolution de la pluviométrie dans la zone sahélienne a connu d’importante variation depuis les années de sécheresse. Cette zone a été considérée par de nombreux auteurs comme la plus affectée par les variations climatiques de ce siècle. Cependant, à l’intérieur de cette même zone, les paramètres climatiques ont des comportements très variables. Ainsi, cette étude a pour objectif d’analyser la variabilité spatio-temporelle de la pluviométrie au Burkina Faso en tenant compte de leur distribution selon les zones climatiques. Pour atteindre cet objectif, les quantités de pluie annuelle de 1921 à 2018 des trois zones climatiques que compte le Burkina Faso ont été mobilisées. Il s’agit des données pluviométriques de Bobo-Dioulasso, Ouagadougou et Dori. Ainsi, pour déterminer les différences de variations temporelles et spatiales de la pluviométrie, les indices de précipitation de chaque zone climatique ont été calculés, puis présenté sous forme de graphiques. Cela a permis d’identifier les années et périodes humides ou sèches. De plus, les ruptures pluviométriques ont été calculées à l’aide du test de Pettitt, permettant de déterminer les différents cycles de l’évolution de la pluviométrie dans les différentes zones climatiques du pays. Les résultats montrent que la pluviométrie a connu une régression depuis 1921 dans les trois localités, mais avec une forte tendance à la baisse à Bobo-Dioulasso où le coefficient directeur de la droite de tendance linéaire est de 0,01. Cependant à Dori la sécheresse est fréquente et rude, puisqu’on y enregistre deux années extrêmement sèches (1926 et 1987). Outre ces résultats, le test de Pettitt a permis d’identifier des ruptures pluviométriques en 1969 à Dori, en 1970 à Bobo-Dioulasso, puis en 1976 à Ouagadougou. L’ensemble de ces résultats montre une différence d’évolution de ce paramètre dans les différentes zones climatiques. Bien qu’étant importante dans les trois zones d’étude, cette variation a un impact important dans zones sahélienne au regard des faibles quantités de pluie qui y tombent et de la fragilité des écosystèmes.
Activity PRN: Exploring Meaningful Occupation 'As and When Required' on a Psychiatric Intensive Care Unit
Authors: Barker Neil
Published: March 2023

Background: Occupational deprivation and barriers to meaningful and purposeful activity are key issues for patients admitted to psychiatric intensive care units (PICUs), resulting in occupational alienation. To increase the frequency of engagement in meaningful occupations, an
intervention named 'Activity PRN' was developed. Method: A quasi-experimental study was completed, measuring the number of ad hoc activities and the frequency of activity engagement on a PICU ward over a period of six months. Therapeutic programme sessions were excluded as this study
measured 'as and when required' activities. Data were collected from 18 patients admitted to the ward over a period of three months prior to the intervention start, and from 22 patients in the following three months during the intervention. Patients were supported to choose personally meaningful
activities, which were then risk-assessed, and resources and activity locations were organised. Activity PRN cards were used to communicate their activity choices to ward staff, and facilitate activity engagement. Results: Data comparison showed greater provision of, and engagement
in, meaningful activities as a result of the intervention. It was found that the terms 'Activity PRN' and 'PRN activities' were used commonly within the ward and hospital. Conclusion: Activity PRN was used as a successful intervention to reduce occupational deprivation and promote occupational
justice on the ward. Further study is required to measure the clinical validity of Activity PRN within inpatient mental health units.
Mafosfamide combine with GMI-HBVac against HBV via Treg depletion in HBV-infected mice
Authors: Lin Qing , Zhong Yiwei , Wang Bin
Published: March 2023

Chronic hepatitis B infection remains a significant worldwide health burden, placing persons at risk for hepatocellular cancer and hepatic fibrosis. Chronic hepatitis B virus (CHB) infection is characterized by elevated levels of immunosuppressive regulatory T cells (Tregs), which can inhibit the function of effector T cells and lead to an insufficient immune clearance response against HBV in the host. Theoretically, suppression of Treg functionality and percentage could increase anti-HBV reactivity in CHB-infected patients, although this has not yet been explored. We attempted to enhance our previously established anti-CHB protocol utilizing the GM-CSF+IFN-α+rHBVvac regimen (GMI-HBVac) by incorporating Mafosfamide (MAF), which has been utilized in anticancer therapy in the past. Intravenous administration of MAF to rAAV8-1.3HBV-infected mice resulted in a dose-dependent reduction of Tregs in the blood, rebounding to pretreatment levels 10 days later. To determine the efficacy of anti-CHB, 2ug/ml MAF was combined with the GMI-HBVac in an HBV-infected animal model as an anti-Treg treatment. When rAAV8-1.3HBV-infected mice were immunized with MAF+GMI-HBVac, peripheral blood Tregs decreased significantly, leading to dendritic cell activation, HBV-specific T cell proliferation, and upregulation of IFN-gamma producing CD8+T cells. In addition, MAF+GMI-HBVac vaccination stimulates T cell infiltration in HBV-infected liver. These conditions may contribute to an enhanced immune response and the clearance of HBV-associated antigens, including serum HBsAg, serum HBcAg, and HBcAg+ hepatocytes. Overall, this is the first indication that MAF was utilized as an adjuvant to deplete Tregs and paired with GMI-HBVac as a unique therapeutic vaccine regimen against established CHB mice to produce a functional cure, as seen by the remarkable clearance of HBsAg.
Unlocking the Therapeutic Potential of Irisin: Harnessing its Function in Degenerative Disorders and Tissue Regeneration
Authors: Zhang Yuwei , Wang Lizhen , Kang Hongyan , Lin Chia-ying , Fan Yu-Bo
Published: March 2023

Physical activity is well-established as an important protective factor against degenerative conditions and a promoter of tissue growth and renewal. The discovery of FNDC5 as the precursor of irisin in 2012 sparked significant interest in its potential as a diagnostic biomarker and a therapeutic agent for various diseases. Clinical studies have examined the correlation between plasma irisin levels and pathological conditions using a range of assays, but the lack of reliable measurements for endogenous irisin has led to uncertainty about its prognostic/diagnostic potential as an exercise surrogate. Animal and tissue-engineering models have shown the protective effects of irisin treatment in reversing functional impairment and potentially permanent damage, but dosage ambiguities remain unresolved. This review provides a comprehensive examination of the clinical and basic studies of irisin in the context of degenerative conditions and explores its potential as a therapeutic approach in the physiological processes involved in tissue repair/regeneration.
Special Issue on Application of Artificial Intelligence Techniques in Production Engineering
Authors: Nakamoto Keiichi , Takasugi Keigo
Published: March 2023

Artificial intelligence (AI) techniques have been behind disruptive innovations in every industry. Based on AI techniques, large amounts of data can be converted into actionable insights and predictions. Manufacturers have frequently faced different kinds of challenges, such as unexpected machinery failures or defective product deliveries. Still, the adoption of AI techniques is expected to improve operational efficiency, enable the launch of new products, customize product designs, and plan future financial actions. Recently, manufacturers have been using AI techniques to improve the quality of their products, achieve greater speed and visibility across supply chains, and optimize inventory management.

Given that the attention and interest in AI techniques has been growing rapidly, it is time that the current state of the art of their practical applications be presented. The main aim of this special issue is to bring together the latest AI research and practical case studies of AI techniques in production engineering.

This special issue features 10 papers related to not only operation automation but also sophisticated skill transfer in manufacturers. Their subjects cover various advancements, such as failure diagnosis, product estimation, process planning, operation planning, and workpiece fixturing in the area of machining. Moreover, the authors boldly strive to apply AI technologies even to complex systems in manufacturing fields such as laser-assisted incremental forming, injection molded direct joining, and parts assembling.

We thank the authors for their interesting papers submitted for this special issue, and we are sure that both general readers and specialists will find the information the authors provide both interesting and informative. Moreover, we deeply appreciate the reviewers for their incisive efforts. Without these contributions, this special issue would not have been possible. We truly hope that this special issue triggers further research on AI techniques in production engineering.
Machine Learning-Based Shape Error Estimation Using the Servomotor Current Generated During Micro-Milling of a Micro-Lens Mold
Authors: Mizuhara Kenta , Nakamichi Daisuke , Yanagihara Wataru , Kakinuma Yasuhiro
Published: March 2023

The demand for the mass production of micro-lens arrays (MLAs) is increasing. An MLA is fabricated through an injection molding process, and its mold is manufactured by a five-axis high-precision machine tool using a small diameter endmill. A visual examination is not available to judge the quality of the mold while machining. Therefore, an effective process monitoring technology must be developed. A promising approach is to apply a servomotor current to in-process monitoring because as long as the servomotor works well, no external sensors, capital investment, or maintenance processes are required. From this perspective, a machine learning-based shape error estimation method using only the servomotor current is proposed. To explore the relationship between the motor current generated during micro-milling and the shape error of the mold, the servomotor current in X-, Y-, and Z-axes was recorded, and the corresponding shape error of the MLA mold was measured after machining. Input data were prepared by converting time-domain servomotor current data to frequency-domain data using short-time Fourier transform and reducing the dimensions of the data via principal component analysis. In terms of a meaningful label for the output data, the average shape error in the machined area corresponding to each window was provided. The input/output relationships were used to train five different machine learning models, and the accuracy of shape error estimation using each model was evaluated. In addition, the estimation accuracies using the X-, Y-, and Z-axes were compared to find the axis that senses the shape error with the highest accuracy. The results show that the non-linear method using the X-axis servomotor current information closest to the machining point achieved the highest shape error estimation accuracy.
Acquisition of Skills for Process Planning Through Eye Tracking When Understanding Mechanical Drawings
Authors: Yoshikawa Takumu , Nakamura Fumihiro , Sogabe Eisuke , Nakamoto Keiichi
Published: March 2023

In parts machining, process planning is typically conducted by skillful operators. The quality of machining is highly dependent on process planning, which determines the operation parameters, such as the operation sequence and cutting tool. To achieve high-quality machining without depending on the skill level of the operators, standardization of process planning is desired. Therefore, it is necessary to extract and generalize skills related to process planning. Furthermore, eye tracking technology is expected to visualize unconscious human behavior. In this study, eye tracking technology is adopted to detect the movement of the operator’s eyes and gather gaze data when understanding mechanical drawings. Gaze data are analyzed using a heat map and bubble chart to identify differences in eye movement according to skill level. The analyzed heat maps indicate that the gazes of the skillful operator are gathered because the operator focuses on the area that is strongly related to the quality of machining. The analyzed bubble charts also indicate that the skillful operator considers the machining process by checking annotations, then understands the shape, and finally verifies the numerical values of the annotations. From the results of interviews performed based on the analysis, the individual skill could be effectively extracted in detail, particularly the skill regarding the operation sequence. Furthermore, the acquired skills are incorporated into a computer-aided process planning system developed in a previous study. The operation sequence is modified to reflect the acquired skills. Machining experiments confirmed the effectiveness of adopting operators’ skills in process planning.
Islamophobia and Terrorism in Indonesia: an Approach on Neuroscience
Authors: Nurkhalis Nurkhalis
Published: March 2023

The stigmatization of Islam with Islamophobia in Indonesia leads to a formless war that makes jihad struggles under the Qur’an and Hadith with a “sacred canopy theory” approach. The interpretation of the words shahid, jihad, and qital turned into a holy warrior who was then suggested as terrorists. This research is based on a literature study approach using library research. This study explains the doctrine of terrorism on hatred of infidels, Westerns, freedom, and mini clothes. This makes terrorism perspectives in terms of hatred change neuroscience from the nervous system to an emotion that culminates in an increase in psychopathy so that increasing dendritic polymorphisms make it easier for synapses to choose the path of tragedy. The growth of Islamophobia (fear of Islam) is a result of tahrif (deviating the meaning of a word) from outsiders’ understanding, including terrorists who alter the core truth of Islam. This diversion of meaning is a way to ease the reacting and maneuvering emotions into brutal and sadistic actions. They prioritized their interpretation of dyspraxia (carelessness), incoordination (loss of control), dysphasia (loss of polite communication skills), and hemianopia (blindness). Unstable neuroscience strongly pushes into false consideration or bad faith in choosing to be a militant Muslim.
Harmony of Relations between Religious People and Conflict Resolution in Kediri
Authors: Dodi Limas
Published: March 2023

Conflicts between religions and religious sects in several parts of Indonesia are still an actual issue and a resolution formulation is still being sought. This paper seeks to reveal the social reality of religious harmony and inter-religious diversity in Kediri, East Java, Indonesia. This research is based on field data by releasing all the opinions of researchers in revealing facts and reality, the researchers propose a pattern of assumptions according to the developed hypothesis. Informants come from several people who have different religious backgrounds. This paper concludes: First, the model of religious harmony and, the same religion in Kediri City is intertwined by compromising character, culture, the authority like scientific profession. Interaction of religious communities is built through the theological-social concept, namely upholding religious principles. Second, socio-religious analysis confirmed that the phenomenon of religious harmony in the city of Kediri. The informants view that religion is right as a social controller that is dynamic and tolerant. Religion is outside the social layer as a fundamental value, that is, as the principle that God wants peace and humans are the same. The socio-religious sub-system is built by authority holders such as religious leaders, intellectuals, prophets, scholars, and the government.
Ethnometodologi dengan Pendekatan Analisis Percakapan Dakwah dalam Channel Youtube Journey of Religion
Authors: Trifita Amjad
Published: March 2023

Percakapan penting dalam dakwah, karena di dalamnya terjadi proses penyampaian informasi melalui komunikasi verbal antara da'i dan mad'u. Menggunakan pendekatan etnometodologi dengan analisis percakapan. Penelitian ini dilakukan dengan tujuan untuk mendeskripsikan atau memahami manusia dalam kehidupan sehari-hari. Susunan dalam analisis percakapan dalam penelitian ini meliputi pergantian pergantian tuturan, susunan urutan, dan pesan dakwah yang terkandung dalam sebuah percakapan. Berdasarkan percakapan di kanal YouTube “Journey of Religions”, peneliti menemukan bahwa percakapan yang terjadi didominasi oleh satu orang. Peran da'i dan mad'u memiliki porsi yang sama dalam mewujudkan sistem dakwah. Bentuk percakapan dalam penelitian ini meliputi tanya jawab, dan kegiatan diskusi yang dilakukan melalui pernyataan penerimaan/persetujuan, dan permintaan penerimaan. Pesan dakwah dalam channel youtube meliputi aspek akidah, syariah dan akhlak yang dapat diambil hikmahnya oleh mad'u.
Meta-Analysis: The Effect of Inquiry Learning Model on Students Critical Thinking Skill
Authors: Praminingsih Indah , Miarsyah Mieke , Rusdi Rusdi
Published: March 2023

This study aims to analyze the effect of the inquiry learning model on students' critical thinking skills, analyze the magnitude of the influence of the inquiry learning model based on education levels, namely SMP and SMA and analyze the magnitude of the effect of using the inquiry learning model based on grade level, namely VII, VIII, X and XI. Fourth, analyze the influence of the use of the inquiry learning model based on the topics of Biology and Science learning materials being taught, namely the Excretory System, Volcanoes, Digestive Systems, Cells, Ecosystems, Circulatory Systems and Environmental Pollution. The method used is meta-analysis, which analyzes 10 articles within a period of 3 years from previous research. The technique used is a meta-analysis technique with descriptive analysis method by analyzing several articles of accredited national journals. Research data collection is done by searching for articles with the help of Google Scholar. The effect size value is obtained from the research that has been done. The effect size related to the whole article regarding the effect of the inquiry learning model on students' critical thinking skills in biology subjects is 1.45 with a very high category. The effect size based on education level is 1.49 for junior high school level and 1.40 for high school level. Effect size based on grade level is 1.65 for class VIII SMP and 1.63 for class XI SMA. The effect size based on the topic of the subject matter is 2.93 on the excretory system material. The conclusion of the study is that the inquiry learning model influences students' critical thinking skills in biology subjects.
Characteristics of Foot Sanitizer Containing Coffee Extract With Variation of Maceration Duration as a Development of Rural Local Potential
Authors: Imaduddin Muhamad , Farikhah Nurul , Haq Ferriana Diean
Published: March 2023

Coffee is a plant that can grow in tropical and subtropical areas with suitable areas, namely at an altitude of 1,000-2,100 meters above sea level, for example, which is often found in Colo village, Dawe district, Kudus City, Indonesia. This study aims to determine the quality of preparations for foot sanitizer from coffee and cinnamon extracts. The method used in this experiment is the experimental method. Coffee and cinnamon extracts can be obtained by maceration or soaking. The coffee extract was given a variation of maceration for 38 and 46 hours. The materials used in this experiment were coffee extract 60%, cinnamon extract 10%, glycerin 10%, ethanol 19.5%, and coffee essence 0.5%. Evaluation of foot sanitizer preparations was carried out in 3 stages, namely organoleptic tests including shape, aroma, color, texture, dry time on the skin, irritation, and level of preference for the formulation. Physical preparation tests include pH, clarity, stability, and homogeneity tests. The antibacterial test was carried out based on the area of the inhibition zone to determine the variation of the best spray preparation foot sanitizer to inhibit bacteria. It can be concluded that the preparation of foot sanitizer F2 (R. 46 hours) is more effective than the preparation of foot sanitizer F (R. 38 hours) with a higher pH value, color, level of preference, and antibacterial activity. It is hoped that in the future the manufacture of foot sanitizers can be produced and disseminated to the wider community.
The Implementation of Case Methods Learning on Water Quality Toward Knowledge and Care Attitude of Students' Environment
Authors: Santri Didi Jaya , Amizera Susy , Anggraini Nike
Published: March 2023

Various activities can cause changes in water quality conditions. One way that can do to change the way people point of view environmental changes is through learning. The aims of this study is (a) to determine the impact of the implementation of cased method learning on students' environmental knowledge and (b) to find out how students care about the environment. This study uses a combined research method (mixed method). This study uses a one-group pre-test, post-test-only design. Quantitative data in this research was obtained through an instrument in the form of a written test. Furthermore, qualitative data was obtained through a tool like a questionnaire regarding students' environmental care attitudes—quantitative data analysis technique using Paired Sample T-Test. Qualitative data analyzed by student attitude questionnaire results. The results showed that cased method learning could increase students' knowledge of water quality problems. it is caused by a significant difference in student knowledge with the value of Sig. (2-tailed) which resulted from SPSS, was 0.00 for the material before and after learning the case method. In addition, students have an attitude of caring for the environment in the good category. Thus the case method learning can be an alternative learning to remind students' knowledge and environmental care attitude, which in the end has implications for management innovations on aquatic ecological problems.
Development of Biology Module Based on Critical Thinking Skills on Even Semester Class X Plante Materials
Authors: Fadillah Etty Nurmala , Dewiyeti Susi , Yuliani Dwi , Fikri Achmad Ali
Published: March 2023

The purpose of this study is: to see the characteristics, feasibility, and practicality of the development of biology modules based on critical thinking skills grade x Plantae material. Modules developed based on the 4-D development model proposed by Thiagarajan are define, design, develop, and disseminate. The product validation was carried out by four validation professors and three biology teachers at SMA Negeri 4 Palembang as practitioners. Limited trials conducted by 15 students in grade x. Data analysis techniques using qualitative descriptive analysis using formulas from Aiken’s V and azwar formulas in excel. The results of the study are as follows: (1) the characteristics of the modules developed are printed using A4 paper. The module consists of a cover, title page, identity page, preface, table of contents, list of pictures, list of tables, instructions for using the module, indicators of critical thinking skills, matter of activities, Plantae material, exercises, summaries, self-reflection, bibliography, glossary , and answer guidelines; (2) biology module based on critical thinking skills on even semester grade X Plantae material is said to be very feasible in terms of the validation results; and (3) the results of practical responses by students when in the field are stated with very practical criteria.

 

Keywords: biology module, critical thinking skills, Plantae
Mediation Role in Solving Sharia Economic Dispute as Civilization Toward Ethical Value of Islam
Authors: Santoso Santoso
Published: March 2023

The aim of this study is to explain the role of mediation in solving sharia economy dispute as civilization toward ethical value of Islam. That it has been practiced since Rasulullah SAW era was through many ways such as shulh, tahkim, and qadha. This study uses qualitative method and data collection is got from observation, direct interview to justice, attorney, lawyer, mediator, and the disputants. Based on the result of the study above is known that the role of mediation in solving sharia economy dispute as civilization toward ethical value of Islam is important and needs to be optimalized. According to Rasulullah SAW teaching, in fact, in a practice, there is failure of mediation in solving sharia economy dispute because the disputants feel that they are right and want to win finally by litigation way with consent or default judgment. Otherwise, mediation practice gives benefits for the disputants and based on Indonesian culture and civilization because solving dispute through mediation can be solved fast, correctly, and cheaply, thus it does not take much energy, time, and thought. In a result,  it can keep privacy, beneficial for parties, and harmless with the result made by parties themselves, that is “win-win solution”. In ethical value of Islam in solving sharia economic dispute, firstly, by al-shulh (peace). Peace in islam is recommended because if there is peace among disputants, they will avoid from hostility. If it does not work, it can be passed by al-tahkim (arbitration) and if it gets stuck, Islam teaches us by al-qadha (Court Process).
Implementasi Akad Wakalah pada Fintech Peer-To-Peer (P2P) Lending di Indonesia
Authors: Mustaqilla Nazhira
Published: March 2023

This study aims to analyze the implementation of wakalah contracts in fintech peer to peer lending in Indonesia. This study uses a qualitative approach with data collection techniques using literature study. The results of this study found that Alami and Investree companies provide financing products based on factoring with Wakalah bil Ujrah contracts that are in accordance with sharia provisions. Meanwhile, the financing products from Dana Syariah Indonesia are not fully in accordance with sharia provisions because there are still misconceptions in practice.
Analisis Kasus Pembatalan Klausula Arbitrase BANI oleh Pengadilan Negeri Jakarta Selatan (Studi Putusan Pengadilan Negeri Jakarta Selatan Nomor: 529/Pdt.G.ARB/2018/PN.Jkt.Sel)
Authors: Khikmah Nurul , Khasabah Karimatul
Published: March 2023

In accordance with Law Number 30 of 1999 concerning Arbitration and Dispute Resolution, that dispute resolution at an arbitration institution is based on a written agreement from the parties to the dispute. The existence of an arbitration clause in the agreement brings legal consequences related to the absolute power of arbitration dispute resolution. This type of research is normative juridical legal research with a statutory approach. The data sources used are secondary data sources which consist of three legal materials, namely primary, secondary and tertiary. The analysis was carried out using an inductive descriptive technique. The results of this study indicate that efforts to annul arbitration can be submitted to the court provided that there are limitative conditions that must be fulfilled according to the alleged elements contained in Article 70 of Law Number 30 of 1999.
Implementasi Etika Bisnis Islam pada Pelaku Usaha Mikro, Kecil, dan Menengah (UMKM) di Kabupaten Kudus
Authors: Sudarsono Sudarsono
Published: March 2023

This study aims to examine business practices carried out by micro, small and medium enterprises (UMKM) in the Kudus Regency area using an Islamic business ethics approach. Islamic business ethics is measured through five principles, namely the principles of monotheism, honesty, benefit, responsibility, and justice. The research method uses descriptive qualitative approach to symbolic interaction. Collecting data using observation and interview techniques as well as using data analysis techniques Miles and Huberman. The results of the study show that Islamic business ethics have not been fully implemented by UMKM actors in Kudus Regency. As for there are several obstacles or obstacles in the application of the principles of Islamic business ethics for UMKM actors in running their business.
Gartland Type III Pediatric Supracondylar Humerus Fracture with Radial Nerve Laceration
Authors: Ito Rina , Otsuka Junko , Horii Emiko , Koh Shukuki
Published: March 2023

Case:

A 6-year-old boy sustained complete radial nerve palsy with a Gartland type III supracondylar humerus fracture (SCHF). Posteromedial displacement of the distal fragment was so severe that the tip of the proximal fragment protruded subcutaneously at the anterolateral aspect of the antecubital fossa. Immediate surgical exploration was performed to reveal radial nerve laceration. Neurorrhaphy after fixation of the fracture resulted in full recovery of radial nerve function 1 year postoperatively.

Conclusions:

Severe posteromedial displacement with complete radial nerve palsy may warrant acute surgical exploration even in a closed SCHF because primary neurorrhaphy may achieve better results than late reconstruction.
Citation Analysis of References Appended in Doctoral Theses in Library & Information Science Submitted to Shodhganga
Authors:   Assistant Librarian, Sri Venkateshwara College of Engineering, Bengaluru 562157, Karnataka, India., N Naveen
Published: March 2023

Citation analysis is one of the popular techniques of bibliometric study that aids scholars in the identification of core journals in their respective domains. The present study is based on 1399 citations used in the 10 doctoral theses of the library and information science department of the University of Calcutta, Mangalore University, Manipur University, Mizoram University, and Gauhati University that are deposited to Shodhganga from 2020. The purpose of this study is to determine the most favored information source, and year-wise distribution of citations as well as to prepare a ranking list of core Journals in the library and information science based on the citation frequency of that journal. Data were gathered and analyzed based on pre-determined criteria. Finally, the conclusion has been drawn from the data analyzed.
RETRACTED: Mitochondrial tRNALeu(UUR) Mutations in Patients with Essential Hypertension
Authors:   Editorial Retraction: International Journal of Biomedicine has retracted the article titled “Mitochondrial tRNALeu(UUR) Mutations in Patients with Essential Hypertension” (Khan I, Lizhe A, Zhiqiang L. Mitochondrial tRNALeu(UUR) Mutations in Patients with Essential Hypertension. International Journal of Biomedicine. 2022,   12(3):444-449. doi: 10.21103/Article12(3)OA18). The above article has been retracted as a result of concerns regarding the use of raw Figures 1-4 by one of the authors upon which the presented research has been based. The article is therefore being retracted due to concerns regarding the reliability of the data. All authors agree to the retraction of the article. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted.”
Published: March 2023

Editorial Retraction: International Journal of Biomedicine has retracted the article titled “Mitochondrial tRNALeu(UUR) Mutations in Patients with Essential Hypertension” (Khan I, Lizhe A, Zhiqiang L. Mitochondrial tRNALeu(UUR) Mutations in Patients with Essential Hypertension. International Journal of Biomedicine. 2022;12(3):444-449. doi: 10.21103/Article12(3)OA18). The above article has been retracted as a result of concerns regarding the use of raw Figures 1-4 by one of the authors upon which the presented research has been based. The article is therefore being retracted due to concerns regarding the reliability of the data. All authors agree to the retraction of the article. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted.”
Assessment of Pancreatic Duct Dilation in Patients with Pancreatic Cancer and Chronic Pancreatitis using Ultrasonography: A Retrospective Study
Authors: Zuhal Y. Hamd Zuhal Y. Hamd , Awadia Gareeballah Awadia Gareeballah , Ahmed E. Abdelsalam Ahmed E. Abdelsalam , Sumaiah S. Alshebl Sumaiah S. Alshebl , Ghaida A. Aldawas Ghaida A. Aldawas , Rawabi  M. Alqahtani Rawabi  M. Alqahtani , Riyaf A. Almuhatib Riyaf A. Almuhatib , Rahaf F. Madani Rahaf F. Madani , Basim Abdullah Salih Alhomida Basim Abdullah Salih Alhomida
Published: March 2023

Background: The present study aimed to assess the main pancreatic duct (PD) in patients with chronic pancreatitis and pancreatic cancer (PC) to determine the prevalence of dilation in both conditions. Methods and Results: A retrospective study was conducted at King Fahad Medical City in Riyadh from December 2019 to March 2020 on the use of ultrasonography to assess PD in patients with PC and CP. The sample included 73 patients: 39 (21 females and 18 males) with PC and 34 (20 males and 14 females) with CP. The diameter of the main PD was measured by ultrasonography. The mean age for PC patients was 61.17±13.96 years, and for CP patients - 42.14±17.08 years (P=0.000). The diameter of the main PD in PC was 0.52±0.22 cm, and in CP, it was 0.51±0.28 cm (P=0.865). Our results suggest that the dilation of the PD is one feature that accompanies PC and CP. In our study, there was no significant difference in the prevalence of dilation in both conditions (64.1% and 64.7%). Additionally, PC is 2.4 times more likely to be associated with diabetes mellitus than CP. Conclusion: PC occurs more commonly in the older age group, while CP occurs more commonly in the younger age group. Most cases of PC and CP were associated with dilation of the PD with no significant difference in the amount of dilation.
Evaluation of Traumatic Knee Joint Injuries Using Magnetic Resonance Imaging
Authors: Elhaj Mona , Elzaki Amin , Alzain Amel , Elnor Hanan , Hassan Wisal , Zidan Mogahid , Kajoak Samih , Alamri Shahd , Aljuaid Hajar , Almuthafari Njood , Alshehri Fi
Published: March 2023

Background: MRI is a widely used modality for diagnosing patients with knee complaints, and it has increasingly replaced diagnostic arthroscopy in this regard. The current research aimed to study the assessment of traumatic knee injuries using MRI, to identify any correlations between the type of tissue damage and age, to determine the ligaments most frequently involved, and to compare the frequency of knee injuries in athletes to those in the general population. Methods and Results: This cross-sectional study included 150 patients with a history of knee injuries who were referred for knee MRI. The study was carried out in the radiology departments of two hospitals (King Faisal Hospital and King Abdulaziz Specialist Hospital, Taif, Saudi Arabia). Medical reports were collected from March 2021 to April 2022. The largest number of affected males were in the age group of 20-30 years; the largest number of affected females were in the age groups of 51-60 years and >60 years. Most athletic patients were in the age group of 20-30 years of age. The anterior cruciate ligament (51.9%) and meniscus (43.1%) were the most affected parts of the knee joint in patients of all ages. Joint effusions and cysts were found in 74.4% and 21.6%, respectively, among all age groups. A torn disc was found in 4 cases, only in male patients aged <20 to 40 years. Conclusion: A non-invasive, radiation-free procedure, MRI facilitates accurate “lesion mapping,” which is important in the diagnosis and follow-up of traumatic knee injuries.
Asthma Control in Multimorbid Patients
Authors: Tribuntseva Ludmila , Budnevsky Andrey , Prozorova Galina , Kozhevnikova Svetlana , Olysheva Irina , Ovsyannikov Evgeniy , Chernik Tatiana
Published: March 2023

Background: The aim of this study was to evaluate the asthma control in multimorbid patients to personalize asthma treatment. Methods and Results: The study involved 237 asthma patients (51 men and 186 women) aged 18 to 78 years (mean age of 52.6±1.3 years). All patients were divided into 3 groups: Group 1 included 59(24.9%) patients with normal body weight (NVW), Group 2 included 69(29.1%) overweight patients, and Group 3 had 109(46.0%) obese patients. The mean BMI was of 23.14±2.84 kg/m2, 27.60±2.58 kg/m2, and 35.82±10.23 kg/m2 in Groups 1, 2, and 3, respectively (F=65.572, P=0.0000). Research methods included numerical rating scale (NRS) for a qualitative assessment of the severity of asthma clinical symptoms, asthma control questionnaire (ACQ-5) to assess asthma control, asthma quality of life questionnaire (AQLQ). Comorbidities were analyzed according to medical records. The mean number of comorbidities among all studied patients was 4.31±0.27: 55(23.2%) people had ≤2 comorbidities, 118(49.8%) people had 3-5 comorbidities, and 64(27.0%) people had ≥6 comorbidities. The Group 3 patients had significantly more comorbidities than patients of Groups 1 and 2 (P=0.000). The mean value of the ACQ-5 results was 0.97±0.32, 1.06±0.53, and 1.82±0.55 in Groups 1, 2, and 3, respectively (F=77.1896, P=0.0000). The level of AC, according to the ACQ-5, had a positive correlation with the number of comorbidities (r=0.5418, P<0.05) and a negative correlation with all scales of the AQLQ: activity limitation (r=-0.6376, P<0.05), symptoms (r=-0.6577, P<0.05); emotional function (r=-0.4535, P<0.05); environmental stimuli (r=-0.4529, P<0.05), and general QOL (r=-0.6504, P<0.05). The asthma course is negatively affected by multimorbidity, which is most pronounced in obese patients. An increase in the number of comorbidities significantly worsens AC in patients of all studied groups, while the worst control level was observed in obese patients. A personalized program for managing multimorbid asthma patients should be developed and implemented, considering the multivariate assessment of treatable signs of disease.
Detection of Actinobacillus actinomycetemcomitans DNA in Patients with Partial and Complete Dentures by Real-Time PCR
Authors: Veseli Enis , Staka Gloria
Published: March 2023

Background: The purpose of the present study was to detect Actinobacillus actinomycetemcomitans (Aa) using RT-PCR in patients with complete and partial edentulism before (T0) and three months after (T3) treatment with removable partial dentures (RPD) and complete dentures (CD), respectively, to compare the data between these two research groups. Methods and Results: The sample comprised 60 patients: 33 men and 27 women, aged 48 to 76 years. The patients were divided into two groups. Group 1 included 30 patients with partial edentulism who were treated with RPD. Group 2 included 30 patients with complete edentulism who were treated with CD. The samples from Group 1 were taken from the gingival sulcus of the abutment teeth by means of sterile paper points. For Group 2, the samples were taken with a sterile swab from the dorsum of the tongue. The samples were taken in T0 and T3 intervals. To detect Aa DNA, we used RT-PCR and ParodontoScreen REAL-TIME PCR Detection Kit (DNA-TECHNOLOGY). Bacterial load levels of species were conventionally represented in logarithm (Lg) of genome equivalents per sample. The results were also presented in three ranges depending on the level of bacterial load: normal (< 4.0Lg), light/moderate (≥4.0 Lg), and severe (>5.0 Lg). The study found a significant difference in the amount of Aa between the T0 and T3 intervals only in patients treated with RPD (0.871.58 Lg vs. 1.28 1.96 Lg, P=0.004). Patients treated with CD, however, did not differ significantly in the amount of Aa between the T0 and T3 intervals (0.030.16 Lg vs. 0). The average bacterial load in patients with RPD was significantly higher than in those with CD three months after treatment (P=0.02) (Table 2). The range of bacterial load levels in the groups is presented in Table 3. Of the 30 patients with RPD, 2(6.7%) had a severe range, 2(6.7%) had a mild/moderate range, and 26(86.7%) had a normal range. The 30 CD patients all had a normal range. There was no significant difference in the prevalence range of bacterial load level with Aa between groups (Fisher's Exact Test = 3.537, P=0.113) / Monte Carlo Sig. (2-sided) / 0.105–0.121). However, in general, RPD causes a significant increase in Aa, so the level of periodontal pathogens may be higher in RPD patients than in CD patients.
Correlation of Herd Immunity to Measles Vaccination Rate and Disease Incidence
Authors: Haxhiu Edita , Humolli Isme , Pllana Donjeta
Published: March 2023

Background: Measles is one of the most contagious diseases faced by humans. Despite considerable progress, measles remains one of the leading global causes of death among children. Methods and Results: The seroprevalence of antibodies against measles in Kosovo was determined with a serological survey of measles. In total, 768 participants aged between 3 days and 45 years of both sexes were included. Enzyme-linked immunosorbent assay results revealed total seropositivity of 74.5% (95% CI: 0.70–0.88) among participants. Those in the unvaccinated 0–1.9-year age group had the lowest seropositivity (33.2%). The 2–6-year age group, which received one dose of the vaccine, had higher seropositivity (78.6%) than the youngest group. The 8–17-year age group, which received two doses of the measles vaccine, had significantly higher seropositivity (91.3%) than the 2–6-year age group. The highest level of seropositivity (93.4%) was observed in the 18–45-year age group. An analysis of sex-specific IgG antigen levels indicated that female participants had significantly higher seropositivity than male participants (P<0.01). Conclusion: The seroprevalence of measles antibodies in Kosovo has not yet reached the required 95% threshold, and the threat of a possible measles epidemic exists. An immunization strategy that targets vulnerable groups and the entire population is required.
Trends in Prediabetes and Diabetes Prevalence in Kosovo: A Comparison of the Results of Steps Survey From 2011 and 2019
Authors: Ramadani Naser , Hoxha-Gashi Sanije , Muçaj Sefedin , Hoxha Ajkuna , Jerliu Naim , Kern Josipa
Published: March 2023

Background: Some years ago, chronic diseases were considered to be a problem for the wealthy and elderly population. Today, chronic conditions affect the poor, young, and middle-aged people in high-income countries. The global prevalence of diabetes mellitus (DM) has been continuously growing for over half a century and has reached pandemic proportions. In the present study, we aimed to estimate the trends in prediabetes and DM prevalence and to determine related risk factors among Kosovo people from 2011 to 2019. Methods and Results: A population-based survey was conducted among people aged 18-69 from April 2018 to June 2019 and those aged 15-64 using the WHO STEPs instrument. Detailed findings on the magnitude of DM and impaired fasting blood glucose (FBG) are presented in this paper. Prevalence of prediabetes in 2011 at 15-64 years was 6.0% (95% CI, 4.6% - 7.9%), and in 2019 at 18-69 years was 6.1% (95% CI, 5.3% - 7.1%), not a significant difference (P>0.05). To avoid bias from different ages, we compared prevalence by age groups. Only in the age group of 35-44 we found a significant difference in the prevalence of prediabetes. In this age group, the prevalence of prediabetes was 2.4% (95% CI, 0.9%-6.1%) in 2011 and 2.7% (95%CI, 0.9%-6.1%) in 2019. In 2019, the prevalence of prediabetes was higher among males than in 2011, when females prevailed. Prevalence of DM in 2011 at 15-64 years was 7.7% (95% CI, 6.0% - 9.7%), and in 2019 at 18 – 69 years was 7.9% (95% CI, 6.9% - 9.0%), not a significant difference (P>0.05). In the age groups of 45-54 and 55-64, we found a significant difference in the prevalence of DM by years. The prevalence of DM at 45-54 years was 13.5% (95% CI, 9.2% - 19.5%) in 2011 and 7.8% (95%CI, 6.0%-10.2%) in 2019 (P=0.032). The prevalence of DM at 55-54 years was 21.6% (95% CI, 15.8% - 28.9%) in 2011 and 13.2% (95%CI, 10.6%-16.3%) in 2019 (P=0.015). The prevalence of DM was higher among females in 2011 and 2019. Conclusion: Results from 2 STEPS in Kosovo show that we have no significant increase in the prevalence of prediabetes and DM in total. At the same time, we found a significant decrease in DM in the age group 45-64.
Pro- and Anti-Inflammatory Blood Cytokines Levels in Women with Moderate and Severe Pelvic Venous Insufficiency
Authors: Darenskaya Marina , Semendyaev Andrey , Stupin Dmitriy , Kolesnikov Sergey , Semenova Natalya , Pesterev Konstantin , Kolesnikova Lyubov
Published: March 2023

The aim of this study was to determine the blood levels of pro- and anti-inflammatory cytokines in patients with moderate and severe pelvic venous insufficiency (PVI). Methods and Results: One hundred and four women with PVI and 30 healthy women (control group [CG]) of reproductive age were examined. The patients with PVI (main group [MG]) were divided into 2 subgroups according to the severity of the disease: MG-moderate (n=63) and MG-severe (n=41). The concentration of pro-inflammatory cytokines (IL-1β, IL-2, IL-6, IL-8), and anti-inflammatory interleukins IL-4 and IL-10 were assessed by enzyme immunoassay using monoclonal antibody panels. Measurements were performed on a microplate photometer. Data analysis showed higher values of pro-inflammatory factors (IL-1β, IL-6, and IL-8) in the MG-moderate than in the CG. The MG-severe, compared with the CG, had high levels of IL-1β, IL-2, IL-6, IL-8, and low IL-10 concentration. In addition, patients of the MG-severe had higher levels of IL-2 than patients of the MG-moderate (P=0.045). The IL-6/IL-10 ratio was characterized by higher values in the MG-moderate and MG-severe than in the CG (P<0.0001). The patients of the MG-severe also had higher levels of the IL-6/IL-10 ratio than patients of the MG-moderate (P=0.020). Conclusion: In patients with PVI with increasing severity of varicose veins, the pro- and anti-inflammatory cytokine balance is progressively disturbed toward the dominance of pro-inflammatory components. The control of these changes in patients is an important component of the design of therapeutic measures and prevention of morphofunctional disorders occurring with the progression of the disease.