bluuebunny/crossref_metadata_2025 huggingface dataset:
Brief history of the development of cognitive neuroscience applied to education in the Dominican Republic 2009-2022
Authors: Gautreaux-Betancourt Rosalba E. , Antúñez-Laffita Vladimir A. , Ordehi-González Dalul
Published: February 2023

La Neurociencia Cognitiva Aplicada a la Educación ha experimentado un desarrollo constante en República Dominicana desde el año 2009. Los conocimientos aportados por las neurociencias a la comprensión del rol de las funciones cognitivas y las emociones en el aprendizaje han revolucionado a docentes a lo largo del país de manera creciente. Sin embargo, una visión creativa e innovadora de una educación que priorice la inclusión, el respeto por la diversidad, la colaboración, la responsabilidad social, el pensamiento crítico, la evidencia científica; necesita de una propuesta innovadora de formación docente en todos los niveles del sistema educativo. Desde el año 2009 hasta 2022 no solo se profundizaron temáticas cruciales de la Neurociencia Cognitiva Aplicada a la Educación en República Dominicana, también se elevaron considerablemente los niveles de divulgación y comprensión de la profunda necesidad de transformación del sistema educativo dominicano para que pueda responder a las propuestas de la neuroeducación.
Bazı Basık Şeftali ve Nektarin Çeşitlerinin Bursa (Türkiye) Koşullarındaki Fenolojik ve Pomolojik Özelliklerinin İncelenmesi
Authors: AHI KOŞAR Dilan , KOŞAR Mevlüt Batuhan , ERTÜRK Umran
Published: February 2023

Şeftali-nektarin dünyada yaygın olarak yetiştiriciliği yapılan meyve türlerinden biridir. Islah programları sonucunda farklı renk, tekstür, şekil, boyut ve lezzete sahip yeni çeşitler geliştirilmiştir. Bunlardan basık şeftali ve nektarinlerin yetiştiriciliği son yıllarda önem kazanmıştır. Çalışma şeftali endüstrisinde önemli bir konuma sahip olan Bursa ekolojisinde bazı basık şeftali ve nektarin çeşitlerinin performanslarını değerlendirmek amacıyla 2016-2018 yılları arasında yürütülmüştür. Çalışmada GF 677 anacı üzerine aşılı Plane Ring, Plane Summer, Plane Gem, Plane Sun, Plane Delicious, Plane Silver, Plane Gold, Plane Super, Plane Star, Plane 222, Plane Top basık şeftali çeşitleri ile Platerina 110 ve Platerina 264 basık nektarin çeşitleri yer almıştır. Çeşitlerin fenolojik gelişim aşamaları, yaprak kıvırcıklığı yaygınlık oranı, verim ve pomolojik özellikleri incelenmiştir. Çalışmada Plane Ring ve Plane Summer çeşitleri en erken (Haziran), Plane Top ve Platerina 264 (Ağustos) ise en geç hasat edilen çeşitler olmuştur. Denemeye alınan çeşitler arasında yaprak kıvırcıklığı yaygınlık oranı % 25.0 (Plane Gold) ile %76.7 (Platerina 264) arasında değişmiştir. Meyve ağırlığı, meyve boyutu ve et/çekirdek oranı yönünden Plane Sun çeşidi daha yüksek değerler verirken, Platerina 110 çeşidi daha düşük değerler vermiştir. Çeşitlerin suda çözünebilir kuru madde miktarı (SÇKM) %13.3 -%18.1; titre edilebilir asit içeriği 0.20 g 100-1 ml -0.68 g 100-1 ml ve olgunluk indeksi 23.0 -82.2 arasında değişmiştir. Çalışmada verim, meyve kalite parametreleri ve hastalık yaygınlık oranı birlikte değerlendirildiğinde Plane Silver çeşidi ön plana çıkmıştır. Ayrıca, Plane Gold çeşidi daha düşük verime sahip olmasına rağmen diğer kalite kriterleri bakımından olumlu sonuçlar vermiştir.
Stock liquidity and stock returns: the moderating role of financial constraints
Authors: Febrianti Veronika Daniar , Saadah Siti
Published: February 2023

Research aims: This study aims to analyze the effect of stock liquidity on stock returns in large and small capitalization companies and the moderating role of financial constraints in the relationship. Design/Methodology/Approach: In this study, panel data analysis was conducted on 113 manufacturing sector companies on the Indonesia Stock Exchange from 2015 to 2019, grouped into small and large capitalization companies. To avoid measurement errors from applying the KZ index, which is very likely to occur, this study used the upper quartile (Q3) of the Debt-to-Equity Ratio (DER) and a dummy variable as an artificial variable to measure financial constraints instead of the KZ index.Research findings: The results highlighted that liquidity is a predictor that could significantly explain the movement of stock returns in this sector. Investors, thus, will require additional compensation in the form of higher returns for holding less liquid stock. The study also found a significant moderating role of financial constraints. Consequently, as the illiquidity of stocks increases, additional greater compensation will be requested by investors on the stocks of companies experiencing financial constraints.Theoretical contribution/Originality: This study provides additional empirical evidence for the studies documented that investors will ask for additional return compensation for stocks with low liquidity, and investors will demand higher additional returns in companies experiencing financial constraints. This finding indicates that liquidity is essential in risk premium forming stock returns.Practitioner/Policy implication: This study can be used for investors or traders when choosing an investment strategy to be carried out.
The role of IT mindfulness in digital technostress and intention to use fintech in Indonesia
Authors: Putriani Santi , Putriana Sinta
Published: February 2023

Research aims: This study aims to investigate how IT mindfulness and digital technostress affect the Y and Z generation of consumers' intentions to adopt Fintech in Indonesia.Design/Methodology/Approach: Consumer respondents from Indonesia's Y and Z generations were selected in this study. SEM-PLS was employed to examine the 309 respondents. Research findings: The study suggested that while IT mindfulness could decrease the adverse effects of digital technostress on the intention to use Fintech and increase it, digital technostress did not influence the intention to use Fintech.Theoretical contribution/Originality: This is the first study to examine how IT mindfulness and digital technostress affect customers in Indonesian Y and Z generation’s intention to use Fintech. The findings of this study add to the body of knowledge on IT mindfulness and will guide future research in this area and also be helpful to innovators and decision-makers in the field of financial technology so that consumers will continue to use it and, ultimately, support sustainable development.
The impact of thin capitalization rule on tax avoidance in Indonesia
Authors: Ramadhan Muhammad Rheza
Published: February 2023

Research aims: This study aims to investigate the impact of the thin capitalization rule on tax avoidance in Indonesia.Design/Methodology/Approach: The analysis used event study regression to overcome the problem of committed variable bias. Research findings: The examination found that, over the entire period, the thin capitalization rule could reduce tax avoidance. However, this study also uncovered that even though tax avoidance was reduced, the company did not pay the tax in the current year but postponed it to the following years. In addition, this study revealed that the thin capitalization rule could only reduce tax avoidance for a sub-sample of non-manufacturing companies. As for manufacturing companies, the thin capitalization rule had no impact on tax avoidance.Theoretical contribution/Originality: This research is the first to examine the impact of the thin capitalization rule on tax avoidance using a suitable method, i.e., event study regression with a staggered setup.Practitioner/Policy implication: This study can show that the thin capitalization rule works well for non-manufacturing companies. However, for manufacturing companies, the Indonesian tax authorities need to consider other ways to reduce their tax avoidance, for example, by creating or updating other specific anti-tax avoidance rules, such as transfer pricing or treaty shopping.
Role of nutrition in curing dysphagia: a case series of five rare cases of severe acute malnutrition with severe megaloblastic anaemia
Authors: Parikh Rujuta , Mudaliar Sangeeta , Prabhu Sanjay , Bodhanwala Minnie
Published: February 2023

Severe acute malnutrition (SAM) is associated with multiple vitamin deficiencies, including vitamin B12. Vitamin B12 deficiency is commonly found in the Indian subcontinent, and has devastating clinical consequences. It leads to megaloblastic anaemia and several other complications. Dysphagia is an unusual symptom of the same. The present study was undertaken to evaluate the reversal of dysphagia with vitamin B12 supplements. A hospital-based retrospective case series was conducted at the B. J. Wadia Hospital for Children. Cases were collected from 19 November 2021, to 25 August 2022. Five children less than two years of age, who presented with complaint of dysphagia, presence of megaloblastic anaemia and concurrent nutritional compromise were evaluated for their clinical profiles, and the outcomes were analysed. We found that dysphagia was a reversible symptom with medical nutrition therapy and injectable B12 therapy in children with SAM who had severe megaloblastic anaemia. The present study has identified the prevalence of dysphagia in cases of SAM with megaloblastic anaemia. This dysphagia is reversible and curable with nutritional rehabilitation and injectable B12 therapy without any further invasive intervention.
Look into their eyes and save their vision: role of primary health care provider in early diagnosis of retinoblastoma
Authors: Gunaseelan Soundharyaa , Pujitha  , Sneha Latha M. , Scott Julius , Khetan Vikas
Published: February 2023

Childhood cancer is not amenable to preventive or screening strategies. The most effective strategy to reduce the cancer burden and improve outcomes, is to focus on early, correct diagnosis followed by evidence-based therapy. When diagnosed early, they are responsive to appropriate therapy and increases survival rates, thereby reducing the need for intensive treatment and reduces the expenditure per child. Retinoblastoma is the most common intra ocular malignancy and is one of the most curable cancers in children. If diagnosed early and treated optimally, not only they are completely cured but a vast majority can have ocular salvage and retain vision. Lack of awareness among general population, diagnostic delays, delays in referral to proper treatment centre, compounded by socio economic factors attributes to the poor outcome in such children. We report a case of 2 years 10 months old girl child whose initial presentation of leukocoria was missed and later presented with advanced retinoblastoma with CNS metastasis.
An unusual case of familial hypophosphatemic rickets
Authors: Bhadke Leny E. , Ingale Suryakant Y. , Shinde Prathamesh S.
Published: February 2023

Rickets is the failure of mineralisation of osteoid and newly formed bones in a child skeleton. It is commonly associated with vitamin D deficiency; however, it can be because of a decrease in serum phosphate level leading to inadequate mineralization of cartilage and bone, consequent skeletal deformities and growth retardation. In hypophosphatemic rickets, there are both inherited and acquired forms, where X-linked hypophosphatemic rickets (XLH) is the most prevalent genetic form and caused by mutations in the phosphate-regulating endopeptidase (PHEX) gene. XLH is associated with growth retardation and bone deformities. This rare variety was diagnosed in a 2 year 4 month old child who had brought by parents with complaint of abnormal gait. In the present case, clinical and radiographic aspects of manifestation of familial hypophosphatemic rickets are discussed.
Foreign bodies in the ear, nose and throat: an experience in a tertiary care hospital
Authors: Parmar Sandip M. , Gupta Lakshay , Chaudhary Meenu
Published: February 2023

Background: The aim of this study was to analyze foreign bodies in terms of type, site, age and method of removal.
Methods: A prospective study was performed in the department of ENT, head and neck surgery in the tertiary care hospital of Muzaffarnagar medical college, Muzaffarnagar, UP. The study population includes the number of patients with ENT FB lodgment who presented in the outpatient department or in the Casualty room during the 1-year study period (June 2021 to May 2022).
Results: A total of 83 patients had FBs in the ear, nose, or throat during the study period. Of the 83 patients, 38 (45.7%) had FB in the ear, 31 (37.34%) in the nose, and 14 (16.8%) in the throat. The FB was animate (living) in 11 (28.9%) patients with FB in the ear and 02 (6.45%) patients with FB in the nose. The FB was inanimate (non-living) in 14 (100%) patients with FB in the throat, in 27 (71.05%) patients with FB of the ear, and in 29 (93.54%) patients with FB of the nose. The FB was removed with or without local anesthesia in 66 (79.51%) patients, only 17 (20.48%) patients required general anesthesia. The most common age group affected was <10 years.
Conclusions: The ear was the most common site for foreign bodies in young children followed by the nasal foreign bodies and throat (esophageal>inhaled) foreign bodies.
Oral, conjunctival and Auricular Kaposi’s sarcoma in a HIV-negative patient : an unusual presentation
Authors: Boubnane Ibtissame , Jebli Salma , Znati Kaoutar , Senouci Karima
Published: February 2023

Kaposi’s sarcoma is an unusual multicentric malignant neoplastic disease, that characterized by the proliferation of spindle-shaped cells. This tumor is habitually involving in the skin of the lower extremities. However, it is  rarely developing in the mucosa or skin of the head and neck. Herein, we report an uncommon presentation of Kaposi sarcoma affecting auricle,oral and ocula rmucosa in an immunocompetent patient. The diagnosis was made on clinical and histopathological finding.
Cardiopatías congénitas en el síndrome de Kabuki. Estudio de 13 pacientes
Authors: DE RUBENS FIGUEROA JESUS , Gómez Díaz-Barreiro Roberta , Yokoyama Emiy
Published: February 2023

INTRODUCCIÓN: El síndrome de Kabuki (SK) es una condición genética rara que se caracteriza por múltiples malformaciones congénitas, retraso en el neurodesarrollo, talla baja, dismorfias faciales características, cardiopatía congénita y anormalidades esqueléticas. Se calcula una frecuencia de 1 en 32,000 nacidos vivos.OBJETIVO: Mostrar la frecuencia de presentación de la afección cardiaca y el tipo de cardiopatía que se presenta en los pacientes con SK de nuestra población.MATERIALES Y MÉTODOS: Estudio retrospectivo de los últimos 10 años de los expedientes, donde se revisaron: edad, género, características clínicas y cardiológicas, tratamiento y evolución. Se realizó estadística descriptiva, usando frecuencias simples y medianas en las variables continuas.RESULTADOS: Se encontraron 13 pacientes con datos clínicos de síndrome de Kabuki cuyas principales características clínicas fueron las dismorfias faciales, anormalidades esqueléticas y manos anormales. El 30% cursó con cardiopatía, las más frecuentes fueron las comunicaciones interauricular e interventricular. Se les dio tratamiento médico a 2 y quirúrgico a los otros 2. No se presentó en nuestro estudio pacientes con dilatación aórtica y/o coartación de la aorta, aunque nuestra muestra es muy pequeña. Hasta la actualidad todos viven con clasificación de Ross I, con un seguimiento de 3 a 10 años.CONCLUSIONES: Es recomendable realizar la valoración cardiológica en cuanto se realice el diagnóstico de síndrome de Kabuki. El pronóstico requiere de seguimiento etiológico clínico con monitoreo anual visual, auditivo y asesoramiento genético.
Seguimiento bioquímico y dosis de medicamentos de EIM del metabolismo intermedio
Authors: Guillén López Sara , López-Mejía Lizbeth , Carrillo-Nieto Rosa Itzel , Belmont Martínez Leticia , Ibarra González Isabel , Fernández-Lainez Cynthia , Vela-Amieva Marcela
Published: February 2023

Los errores innatos del metabolismo intermedio (EIMi) son un grupo heterogéneo de enfermedades monogénicas pertenecientes al grupo de las enfermedades raras (ER), que afectan vías metabólicas de la síntesis o catabolismo de los hidratos de carbono, aminoácidos o lípidos.1 Estas enfermedades conllevan anormalidades bioquímicas que pueden cuantificarse en diferentes fluidos biológicos, lo que permite su diagnóstico.
Discrimination Against Gay and Transgender People in Latin America: A Correspondence Study in the Rental Housing Marke
Authors: Abbate Nicolás , Berniell Inés , Coleff Joaquín , Laguinge Luis , Machelett Margarita , Marchionni Mariana , Pedrazzi Julián , Pinto María Florencia
Published: February 2023

We assess the extent of discrimination against gay and transgender individuals in the rental housing markets of four Latin American countries. We conducted a large-scale field experiment building on the correspondence study methodology to examine interactions between property managers and fictitious couples engaged in searches on a major online rental housing platform. We find evidence of discriminatory behavior against heterosexual couples where the female partner is a transgender woman (trans couples): they receive 19% fewer responses, 27% fewer positive responses, and 23% fewer invitations to showings than heterosexual couples. However, we find no evidence of discrimination against gay male couples. We also assess whether the evidence is consistent with taste-based discrimination or statistical discrimination models by comparing response rates when couples signal high socioeconomic status (high SES). While we find no significant effect of the signal on call-back rates or the type of response for high-SES heterosexual or gay male couples, trans couples benefit when they signal high SES. Their call-back, positive-response, and invitation rates increase by 25%, 36% and 29%, respectively. These results suggest the presence of discrimination against trans couples in the Latin American online rental housing market, which seems consistent with statistical discrimination. Moreover, we find no evidence of heterosexual couples being favored over gay male couples, nor evidence of statistical discrimination for gay male or heterosexual couples.
Trade relationship of Vietnam from the perspective of the China-US trade War 2019: A comparison study using the Gravity Model
Authors: Huyền Trần Khánh
Published: February 2023

Purpose: This study aims to evaluate the determinants of the trade relationship between the two largest trading partners of Vietnam, the United States, and China.

Methodology: This study is completed using the gravity model for time series data from 1986 to 2019.

Main Findings: The study found that the economic growth rate plays a crucial role in stimulating the trade flow. Both trade relationships fit with the practical approach of the gravity model, stating that trade flow increases between countries with different income levels. The most important finding of this study lies in the results regarding the impact of the trade war 2019 between the United States and China. The trade war 2019 can be compared with the study in previous 2015 on trade agreements between ASEAN and China produced trade diversion.

Implications: As China expands its markets among ASEAN countries, Vietnam should diversify its export markets to improve its export flow in the trade agreement. But export and import correlation compared the effect of US – VN and China – VN change in the period of a trade war after five years.

Novelty: This paper has studied the determinants of trade flows between VN-US and VN-CN to provide a detailed comparison. The input and output stream in gravity frame.
A literature review of cashew apple processing
Authors:   Université Félix Houphouët-Boigny d’Abidjan, Gnagne AAGB , Soro D ,   Institut National Polytechnique Houphouët-Boigny de Yamoussoukro, Ouattara YA , Koui EW , Koffi E
Published: February 2023

The cashew tree, a tree adapted to tropical areas was introduced in Africa by European explorers. Its cultivation in some African countries has been done to stop the advancing Sahara desert and to reduce soil erosion. The cashew fruit consists of a nut being the real fruit, and a fleshy apple which is considered the pseudo-fruit. The nut represents the major point of interest in cashew tree cultivation. Despite being a commodity of international trade, cashew apple suffers from low commercial interest. As a result, millions of tons of cashew apple rot in orchards without any form of processing every year. Gradually, its excellent properties are attracting the attention of the scientific world and industrialists with a view to enhancing its commercial and food value. This review reports different methodologies of transforming cashew apple. Some potential products include juice and potential cocktails. Juice clarified by tangential microfiltration was almost cleared of tannins, giving good clarity and a pleasant taste. A stabilized cocktail of cashew apple and pineapple juices using 10% ginger aqueous extract was judged good as it retained prime quality for 7 days at 4 - 5 °C, with significant improvement of vitamin C and protein content (p ≤ 0.05). Obtaining an amber dry wine of 12.6% alcohol with no significant difference (p < 0.05) from commercial grape wine was demonstrated using Saccharomyces cerevisiae as a fermenting agent. Ethanol of 97.8% purity was also obtained by immobilized cells of S. cerevisiae on silica gel. Edible vinegar of 4% acidity with similar characteristics as commercial varieties was produced from the juice. Jam and a viscous syrup of 80 °Brix which was found to be rich in glucose and fructose was also produced. A generator powered by 6% cashew apple biofuel with the rest being gasoline revealed reduced fuel consumption compared to the use of gasoline alone, though engine behavior during its operation was a concern. Also, cashew apple flour has been used for the manufacture of composite biscuit formulated with or without wheat flour. Thus, cashew apple could become a source of additional incomes for peasants by being the origin of creation of companies through these various developed technologies. Key words: cashew apple, processing, juice, alcohol, vinegar, jam, syrup, flour, biofuel
Within-year changes in households’ access to food in a unimodal climate rural area of Benin Republic
Authors:   Université d’Abomey-Calavi, Nagassi WJV , Fanou-Fogny N , Mitchikpè CES
Published: February 2023

Food insecurity is a concern in Benin not only because of seasonal variations in food availability but also the limited access to food experienced by some households. This study analysed the effect of seasonality on household access to food in a rural area of Benin characterised by a unimodal climate. One hundred and seventy volunteer households were recruited in the study area and monitored during the increased, intermediate and decreased (or lean) food availability periods (FAPs) from September 2018 to July 2019. Socio-demographic data were collected during individual interviews with household heads and used to describe the sample. Data on households’ access to food were collected on a bimonthly basis using a food consumption score (FCS) questionnaire. Food consumption scores were used to divide the households into three food consumption groups (FCGs): poor (FCS ≤ 21), borderline (21.5 ≤ FCS ≤ 35) and acceptable (FCS > 35). Generalized estimate equation (GEE) was used to compare FCGs among the repeated measures. The principal occupation of household heads was agriculture (72.9%) and the mean household size was 6.8±3.6 persons. The FCS ranged from 59.7±15.5 to 69.4±15.9. The lowest FCS was recorded in September (intermediate FAP) whereas the highest was obtained in May (lean FAP). All the households (100%) had acceptable food consumption during the increased FAP (November to January). The proportion of households with acceptable food consumption was 91% in September and decreased from 99% in March to 90% in July, that is, during the lean FAP. On the other hand, the proportion of households with borderline and poor food consumption was 9% in September and increased from 1% in March to 10% in July. The proportions of FCGs obtained in November, January, March and May significantly differed from that of July (p<0.05) whereas there was no significant difference between September and July. Households had frequent (5 to 7 days/week) and regular (all months) intakes of starchy staples, vegetables, meats and fish. In contrast, the frequency of pulses and fruits consumption varied between months. In conclusion, the lean FAP (May to July) and the following intermediate FAP (September) are characterised by a deterioration in households’ access to food. The variation of pulses and fruits consumption throughout the year is the result of food insecurity and constitutes a major risk factor for micronutrient malnutrition for household members. Keys words: Households, access to food, food consumption score, longitudinal studies, unimodal climate, Benin Republic
Effect of covi-soup on CD4 cell count and haemoglobin among patients with diabetes type II and hypertension in Kakamega county, Kenya: A randomized control trial
Authors:   Masinde Muliro University of Science and Technology, Sagam C , Kivelenge A , Olayo R , Wanjala C , Mutai C , Wesonga B , Mutuli L , Situma J
Published: February 2023

Type II diabetes mellitus (DM) and hypertension (HTN) diseases are part of the world’s challenges in achieving sustainable development goals. Cases of type II diabetes mellitus and hypertension diseases in low and middle-income countries are becoming a concern. Type II diabetes mellitus is an inflammatory disease. When there is inflammation the immune system is triggered and haemoglobin level is affected. While there have been numerous strategies to address the issue, these efforts have not been sufficient to guarantee a reduction in disease severity. This was an experimental study conducted in Kakamega County, Kenya. It employed a randomized control trial approach, with two groups: treatment and control. Systematic random sampling was used in identifying participants and simple randomization was used to allocate the respondent to the intervention groups. Sample sizes of 34 (treatment group) and 30 (control group) were used to produce quantitative data. This study evaluated the effect of COVI-soup on haemoglobin (Hb) and cluster of differentiation 4 (CD4) cell count of patients living with both type II diabetes mellitus and hypertension. The treatment group received COVI-soup (a soup composed of butternut squash, ginger, garlic, sunflower pepper, chia seeds and turmeric) while the control group was on a rice soup. Statistical Packages for Social Science (SPSS) version 20 was used in the data analysis. A paired student t-test was used to determine the effect of COVI-soup on Hb and CD4 cell count. There was a positive effect in CD4 cell count in the treatment group (P =0.001) whereas there was no significant effect in the control group (P =0.267). The mean change in CD4 cell count in the treatment group was 97 cells/ul and in the control 75 cells/ul. There was a positive effect (increase) on hemoglobin levels in the treatment group (p=0.0001) whereas there was no significant effect in the control group (p =0.126). The hemoglobin mean change in the treatment group was 3.9 g/dl and in the control 0.5 g/dl. Therefore, COVI-soup had a positive effect on hemoglobin and CD4 cell count levels among patients with both hypertension and type II diabetes mellitus. Key words: Hemoglobin, CD4 cell count, COVI-soup, Rice soup, diabetes type II, hypertension
Effect of immobilized hyaluronidase and subtilisin enzymes on the ultrastructure of human conjunctival epithelial cells
Authors: Zabanova V. E. , Fursova A. Zh. , Bondarenko N. A. , Bgatova N. P. , Zateev A. V. , Madonov P. G.
Published: February 2023

The use of enzyme preparations is a traditional trend in various fields of medicine. The usage of immobilized enzymes hyaluronidase (IG) and subtilisin (IS) seems to be very promising for the treatment of damage to the ocular surface. The aim of the study was to establish the nature of changes in the ultrastructural organization  of human conjunctival epithelium under the influence of  immobilized hyaluronidase and subtilisin in vitro. Material and methods. In the experiment, a culture of normal cells of the human conjunctiva Chanqconjunctiva, clone 1–5 C-4, was seeded in 96well plates in the amount of 2 × 104 cells/well, after 24 h the medium was removed, Eagle’s medium MEM and fetal calf serum were added and cells were cultured for another 48 h. 5 experimental groups were formed: group 1 – without drugs (except for the composition of the incubation scheme), groups 2 and 3 – with IS at a concentration of 37 and 150 U/ml, respectively, groups 4 and 5 – with IG at a concentration of 37 and 150 U/ml, respectively. After preparation of cell preparations under a JEM 1400 electron microscope (Japan), ultrathin sections of 70–100 nm were studied at ×1000 magnification. Results. The article presents the results of electron microscopy of a culture of normal cells of the human conjunctiva in 5 experimental groups of cells with a description of changes in cytoarchitectonics under the influence of IG and IS. Conclusions. The introduction of immobilized enzymes into human conjunctival cell culture at a low dose (37 U/ml) affects the organization of cells without cytotoxic effects, while increasing the dose directly correlates with the occurrence of a cytotoxic effect.
Day and Night. Activities by and for the Children from El Refugio in Ancient Neighbourhoods of the Historic Centre of Puebla
Authors: Hernández Sánchez Adriana , De La Torre Sánchez Christian Enrique
Published: February 2023

The purpose of the following investigation is to understand how children from the old historic district El Refugio (or Barrio del Refugio) of the city of Puebla (Mexico) live in public spaces and what their days and nights look like. It is extremely important to understand the reasons for their appropriation of various places in the city because it allows one to explore the conditions in which they manifest autonomous attitudes. This article is therefore not only about customs and culture, but also about everyday relationships with the environment. Children are also involved in the activities of the group Re Genera Espacio (RGE) and the team of Benemérita Universidad Autónoma de Puebla (BUAP) in the development of all kinds of educational, artistic, and social activities. Among the most important results obtained is the observation that safety conditions are created by children in independent groups which move to other neighbourhoods (“barrios”), such as San Antonio and Santa Anita. Children make the street their space because they have important knowledge of the area.
Solidarność jako zasada życia społecznego w nauczaniu Jana Pawła II
Authors: Kowalczyk Ks. Stanisław
Published: February 2023

The paper has three parts. The first part concerns the solidarity principle’s genesis. Its philosophical base is the personalistic
anthropology, which speaks about prosocial nature of man and its active participation in the social life. The biblical-theological base
of solidarity are: personal dignity of man comme God’s image, person and learning of Christ, community of the Church. The second part
of paper discusses elements ontological-anthropological and biblical-ethical which are necessary in the realisation of solidarity’s principle.
They are following: pluralism of equal persons and societies, its dialogue, co-production of common good by honest work, integral
development economic and intelectual-cultural, equality, social justice and love, peace and reciprocal settlement. The thirt part of paper
speaks about three circles of application of solidarity’s principle; namely: solidarity professional-working – defend of rihts of workers,
solidarity general-social of nation and state – protection of economic and political human rihts, solidarity international of humanity – trend
towards peace and prosperity.
Wspólnotowy charakter wolności na podstawie myśli antropologicznej Karola Wojtyły
Authors: Mizdrak Inga
Published: February 2023

One of the main themes in the 20th century disagreements about man is the question of freedom, which seems to be the most
complicated and, at the same time, intriguing phenomenon in the characteristics of the human subject. Karol Wojtyła suggests positioning
freedom not only in the horizon of the irreducibility of the person as a subject, who autonomously decides about self and gives direction to
own activities, but also in the area of interpersonal community. Being a person as a free subject appears as “in relation to” or “referring to”
(something, somebody). We respond to values by making choices. The world of values is extremely rich and varied. It also encompasses
other people, who are in relation to one another. Therefore, to be a person means more than just to be for oneself, in oneself and by oneself.
To be a person is to be in relation to other people and to values.
The community-oriented character of freedom is focused on in the philosophical writings by Karol Wojtyła, who on numerous
occasions emphasizes the fact that a person may reach fulfilment through another human being, in a community with others, without losing
anything of own subjectivity or individuality. Wojtyła wishes to deal with the problem of one of the fundamental conditions upon the
fulfilment of which the community I-You may become a reality of subjects fulfilment. In order to achieve this purpose, Wojtyła undertakes
analyses
of participation, solidarity, community, whose proper specification in the perception of freedom aims at emphasizing the sense of man’s
existence together with other human beings, on the one hand, and the purpose of man’s earthly journey, on the other hand.
Znaczenie recepcji dorobku Bronisława Malinowskiego dla rozważań etyki gospodarczej nad kryzysem finansowo-gospodarczym
Authors: Szulczewski Grzegorz
Published: February 2023

The paper presents two theories from the area of cultural anthropology. The first is B. Malinowski, who criticized economism and
moralism. I present further stages of this criticism, with special importance placed on the concept of homo oeconomicus. Malinowski also
showed how moral norms are implemented in primitive cultures by means of magic, cults, customs and rituals and rites. Another important
section is devoted to Malinowski’s analysis of how cultural institutions were important for stable functioning of primitive communities.
They sheltered those communities form crisis of the kind that we experience today. The second theory is economical ethics of K. Hofman,
one of the newest achievements of German business ethics. So works of cultural anthropology are worth being read again.
Mobbing jako problem etyki w zarządzaniu
Authors: Kowal Jolanta , Pilarek Grażyna
Published: February 2023

The positive company image and its good reputation are usually results of ethical and honest behaviour towards employees and may
cause competitiveness and benefits increase, customer satisfaction and new job places creating. However it occurs often in dynamically
developing firms that ethical norms are not kept and this process is observed by lack of equal chances to get a job – people without
connections remain without work. Due to different research the very serious problem is a phenomena of mobbing.
Psychological terror or mobbing in working life involves hostile and unethical communication which is directed in a systematic
manner by one or more individuals, mainly toward one individual, who, due to mobbing, is pushed into a helpless and defenceless position
and held there by means of continuing mobbing activities. These actions occur on a very frequent basis (statistical definition: at least
once a week) and over a long period of time (statistical definition: at least six months´ duration). Because of the high frequency and long
duration of hostile behaviour, this maltreatment results in considerable mental, psychosomatic and social misery.
Una revisión bibliométrica de la literatura sobre innovación social
Authors: Cruz-Cabrera Blasa Celerina , Valadez-Solana Brenda Dennís , Regino-Maldonado Juan , Acevedo-Martínez Jorge Antonio , Ríos-Castillo Maricela
Published: February 2023

La innovación social (IS) es un campo de investigación relativamente nuevo que está generando interés en la comunidad científica. Este artículo presenta una revisión bibliométrica de la investigación sobre IS en el periodo 1971-2021. Las referencias se obtuvieron de la base de datos Scopus. Se identificó y clasificó la investigación más relevante del campo de IS tomando como unidades de análisis revistas, países, instituciones, autores y publicaciones. Se analizaron 1796 publicaciones y se utilizaron los métodos bibliométricos de análisis de desempeño y mapeo científico. En el análisis de desempeño se manejaron varios indicadores bibliométricos como el índice h, la productividad y las citas. Además, el software VOSviewer se utilizó para mapear el material bibliográfico. El mapeo científico usó las técnicas de cocitas y coocurrencia de palabras clave. Los resultados mostraron que la investigación en IS ha aumentado considerablemente desde 2009. Reino Unido se posicionó como el país más productivo e influyente en este campo. La revista Sustainability mostró la mejor combinación de productividad e influencia en el campo de la IS. Frank Moulaert resultó ser el autor más importante de investigaciones sobre IS. Los temas emergentes de investigación relacionados con la IS fueron la sustentabilidad y el emprendimiento social.
Códigos JEL: O31, Y10, Z00
Recibido: 11/02/2022. Aceptado: 14/09/2022. Publicado: 01/12/2022.
Internalization of Local Traditional Values in A Plurality Community: Interreligious Relations in Sawangan, Magelang
Authors: Setiyani Wiwik , Effendi Masitah , Yuldashov Sodik Okbaevich
Published: February 2023

The Sawangan community is one of the references in building harmony between religious people. Local Traditions have made it a symbol of community identity as well as a unifying relationship between religions. This article will explain the local traditional values ​​of the Sawangan community. The research method was carried out by in-depth interviews. Peter L. Berger's theory becomes an analytical tool in finding the process of internalizing local traditions in a plural society. The object of the research was carried out at the Sawangan Magelang location. The research finding is that the diversity of the community can inspire because, from upstream to downstream, there are synergies in building communities through local traditions. Friction between communities can be addressed quickly and responsively. People get comfort in carrying out activities through various cultural arts activities. Various religious backgrounds are united in the frame of local traditions as well as become the glue between the people. Local traditions internalize in society to create a peaceful society that is tolerant of all religions and beliefs. The spirit of togetherness fosters empathy and sympathy to complement each other in their work so that local traditional values ​​have internalized the Sawangan community.
Öğretmen Adaylarının Konuşmaya Yönelik Kaygılarını Etkileyen Faktörler: Bir Yol Analizi Çalışması
Authors: DEMİR Selvi
Published: February 2023

Bu araştırma; öğretmen adaylarının konuşma kaygıları üzerinde konuşma tutumları ve öz yeterlik inançlarının doğrudan ve aracılık etkisinin yanı sıra konuşma tutum ve öz yeterlik inançlarının duygusal ve ruhsal zekâya aracılık etkisinin yol analizi aracılığıyla belirlenmesini amaçlayan betimsel bir çalışmadır. Araştırmanın katılımcılarını 2021-2022 akademik yılında bir devlet üniversitesinde okuyan 693 öğretmen adayı oluşturmaktadır. Yaşları 16-35 yaş aralığında değişen öğrencilerin 502’si kadın, 190’ı erkeklerden oluşmaktadır. Araştırma verilerinin analizinde SPSS 23 ve Mplus 7 programlarından yararlanılmıştır. Spss aracılığıyla verilerin normalliği, değişkenler arasındaki korelasyon değerleri, değişkenlerin toplam skorlarının ortalamaları ve standart sapmaları test edildikten sonra verilerin yol analizinde ise Mplus kullanılmıştır. Analizlerde “konuşma kaygısı,” “konuşma tutumu”, “konuşma öz yeterliği”, “duygusal zekâ” ve “ruhsal zekâ” olmak üzere tüm değişkenler sürekli değişken olarak kullanılmıştır. Modele ilişkin uyum indeksleri şu şekildedir: ki-kare, χ2 (2) = 5.9; p =.05, CFI =.99, TLI =.97, RMSEA =.05 (90% CI: .00, .11) ve SRMR =.01. buna göre yol modelinin model uyum istatistikleri çok iyi bir model uyumu olduğunu göstermektedir. Araştırma sonuçları doğrultusunda öğretmen adaylarının konuşma kaygıları üzerinde konuşmaya yönelik tutum ve öz yeterlik algılarının doğrudan ve aracılık etkisinin bulunduğu tespit edilmiştir. Buna ek olarak araştırma sonucunda öğretmen adaylarının konuşma kaygıları üzerinde duygusal ve ruhsal zekânın dolaylı etkisinin bulunduğu ve bu etkiye öğretmen adaylarının konuşmaya yönelik tutum ve öz yeterlik algılarının aracılık ettiği belirlenmiştir. Elde edilen bulguların ilgili alanyazın bağlamında değerlendirilmesinin ardından birtakım önerilere yer verilmiştir.
THE EFFECT OF INTRINSIC MOTIVATION AND ATTITUDE TO FULFILLMENT OF IMMUNIZATION DURING PANDEMIC
Authors: Aulia Devika , Wittiarika Ivon Diah , Irwanto Irwanto
Published: February 2023

Background: The milestone in protecting the nation's next-generation from disease is to provide basic immunization as natural protection against specific infections. Covid-19 has hit Indonesia since early 2020, disrupting all aspects of life, especially health, which is manifested in a decrease in basic immunization coverage. The purpose of this study was to determine the influence between intrinsic motivation and mother's attitude towards the fulfillment of basic immunization during the Covid-19 pandemic. Methods: The research method used is analytic observation using the Spearman test with a p-value <0.05. Respondents of this study were mothers with children aged 0-12 months at Puskesmas Jatibening Baru, Bekasi, as many as 37 respondents with the total sampling method. The research instrument was an online questionnaire with variables of intrinsic motivation and mother's attitude. Results: Based on research analysis using the Spearman test, the p-value = 0.376 and the Spearman correlation coefficient of 0.150 to see the effect between mother's intrinsic motivation and the status of basic immunization fulfillment during the Covid-19 pandemic. The results of the p-value to see the effect of mother's attitude with basic immunization fulfillment status during the Covid-19 pandemic was 0.182, and the Spearman correlation coefficient was 0.224. Conclusion: There is no effect between intrinsic motivation and mother's attitude towards the fulfillment of basic immunization during the Covid-19 pandemic.
 
Keywords : Attitudes; Basic Immunization; Covid-19; Intrinsic Motivation
An overview of intelligent image segmentation using active contour models
Authors: Chen Yiyang , Ge Pengqiang , Wang Guina , Weng Guirong , Chen Hongtian
Published: February 2023

The active contour model (ACM) approach in image segmentation is regarded as a research hotspot in the area of computer vision, which is widely applied in different kinds of applications in practice, such as medical image processing. The essence of ACM is to make use ofuse an enclosed and smooth curve to signify the target boundary, which is usually accomplished by minimizing the associated energy function by means ofthrough the standard descent method. This paper presents an overview of ACMs for handling image segmentation problems in various fields. It begins with an introduction briefly reviewing different ACMs with their pros and cons. Then, some basic knowledge in of the theory of ACMs is explained, and several popular ACMs in terms of three categories, including region-based ACMs, edge-based ACMs, and hybrid ACMs, are detailedly reviewed with their advantages and disadvantages. After that, twelve ACMs are chosen from the literature to conduct three sets of segmentation experiments to segment different kinds of images, and compare the segmentation efficiency and accuracy with different methods. Next, two deep learning-based algorithms are implemented to segment different types of images to compare segmentation results with several ACMs. Experimental results confirm some useful conclusions about their sharing strengths and weaknesses. Lastly, this paper points out some promising research directions that need to be further studied in the future.
Statistical stegdetectors performance by message re-embedding
Authors: Progonov Dmytro
Published: February 2023

State-of-the-art stegdetectors for digital images are based on pre-processing (calibration) of analyzed image for increasing stego-to-cover ratio. In most cases, the calibration is realized by image processing with enormous set of high-pass filters to obtain good estimation of cover image from the stego one. Nevertheless, the efficiency of this approach significantly depends on careful selection of filters for reliably extraction of cover image alterations that are specific for each embedding method. The selection is non-trivial and laborious operation that is realized today by training of convolutional neural networks, such as Ye-Net, SR-Net to name but a few. The paper is devoted to performance analysis of alternative approach to image calibration, namely message re-embedding into analyzed image. The considered method is aimed to increasing stego-to-cover ratio by amplification of cover image alterations caused by message hiding. The analysis was performed on ALASKA and VISION datasets by usage of stegdetector based on SPAM model of covers. Messages were re-embedded according to state-of-the-art adaptive methods HUGO, S-UNIWARD, MG and MiPOD. Proposed approach allows significantly (up to 20%) decreasing detection error even in case of low payload of cover image (less than 10%) where modern stegdetectors are ineffective.
Quantities of points on some Edwards curves
Authors: Rybak Oleksandr
Published: February 2023

The Edwards curves of the form x2 + y2 = 1 + dx2y2 are investigated in this article. An exact formula for the quantity of points on x2 + y2 = 1 + dx2y2 over a field Fp is obtained for odd prime numbers p. The special attention is paid to the curves with exactly p+1 points over the field Fp. These curves are called supersingular. They are not recommended for usage in cryptography, because their structure is relatively simple. The supersingularity of the curve is proved for any prime p = 4m+3. Also, some other values of d, for which x2 + y2 is equivalent to 1 + dx2y2 (mod p) is supersingular, are found.
Construction of Proactive Monitoring Model using Forecasting Techniques in the SCOM Software Complex
Authors: Soldatova Kateryna , Nosok Svitlana
Published: February 2023

The majority of companies depend on their information systems, the stability of infrastructure operations and the failover of computing resources. Various monitoring tools are mostly used to automate the benchmarking process of company.
The company that has a large distributed infrastructure should pay close attention to this process, as it makes the state of operations difficult to maintain, and increases the probability of the loss of functionality for errors or even shutdown of some servers. The one of solutions is reactive monitoring.
Reactive monitoring is a technique where system administrators use monitoring tools to continuously collect data that determine the active and current status of information system environment. Measurements obtained from real-time monitoring tools illustrate the performance data of current information environment.
However, if we discuss the main metrics of system resources, such as the level of processor load, RAM or disk usage, their change can be quite fast. And for servers that are responsible for critical functions, the problem of full resource usage is important. This problem can be solved with proactive monitoring.
Proactive monitoring is a set of monitoring tools that not only collect real-time information, but also predict possible failures before they impact end users[1].
The purpose of this article is to choose methods of time series forecasting for the resources load that are going to be combined into a single hybrid method. The final solution will be used in the management pack of software complex System Center Operations Manager (SCOM) that is widely used by companies with large infrastructure[2]. The forecasting methods such as Least squares, SMA and EMA were considered in this work.