bluuebunny/crossref_metadata_2025 huggingface dataset:
Vaccine Effectiveness Against SARS-CoV-2 Infection and Severe Outcomes in the Maintenance Dialysis Population in Ontario, Canada
Authors: Oliver Matthew J. , Thomas Doneal , Balamchi Shabnam , Ip Jane , Naylor Kyla , Dixon Stephanie N. , McArthur Eric , Kwong Jeff , Perl Jeffrey , Atiquzzaman Mohammad , Singer Joel , Yeung Angie , Hladunewich Michelle , Yau Kevin , Garg Amit X. , Leis Jerome A. , Levin Adeera , Krajden Mel , Blake Peter G.
Published: March 2022

Significance Statement

Serology studies of coronavirus disease 2019 vaccines in the maintenance dialysis population have found weak antibody responses to one dose of vaccine and lower responses to two doses than among healthy controls. However, it is undetermined how these serologic responses correlate with the prevention of infection, hospitalization, and mortality in this immunosuppressed population. We identified 13,759 individuals receiving maintenance dialysis in Ontario, Canada. One dose of vaccine reduced the risk of infection and severe outcomes by 41% and 46%, respectively, compared with unvaccinated patients. Two doses of vaccine reduced the risk of infection and severe outcomes by 69% and 83%, respectively. The study confirms that coronavirus disease 2019 vaccination is effective in the maintenance dialysis population.

Background

Vaccination studies in the hemodialysis population have demonstrated decreased antibody response compared with healthy controls, but vaccine effectiveness for preventing SARS-CoV-2 infection and severe disease is undetermined.

Methods

We conducted a retrospective cohort study in the province of Ontario, Canada, between December 21, 2020, and June 30, 2021. Receipt of vaccine, SARS-CoV-2 infection, and related severe outcomes (hospitalization or death) were determined from provincial health administrative data. Receipt of one and two doses of vaccine were modeled in a time-varying cause-specific Cox proportional hazards model, adjusting for baseline characteristics, background community infection rates, and censoring for non-COVID death, recovered kidney function, transfer out of province, solid organ transplant, and withdrawal from dialysis.

Results

Among 13,759 individuals receiving maintenance dialysis, 2403 (17%) were unvaccinated and 11,356 (83%) had received at least one dose by June 30, 2021. Vaccine types were BNT162b2 (n=8455, 74%) and mRNA-1273 (n=2901, 26%); median time between the first and second dose was 36 days (IQR 28–51). The adjusted hazard ratio (HR) for SARS-CoV-2 infection and severe outcomes for one dose compared with unvaccinated was 0.59 (95% CI, 0.46 to 0.76) and 0.54 (95% CI, 0.37 to 0.77), respectively, and for two doses compared with unvaccinated was 0.31 (95% CI, 0.22 to 0.42) and 0.17 (95% CI, 0.1 to 0.3), respectively. There were no significant differences in vaccine effectiveness among age groups, dialysis modality, or vaccine type.

Conclusions

COVID-19 vaccination is effective in the dialysis population to prevent SARS-CoV-2 infection and severe outcomes, despite concerns about suboptimal antibody responses.
Manejo del suicidio en prensa
Authors: Vargas Moranth Rusvelt , Alcocer-Olaciregui Adalgisa , Bilbao -Ramírez Jorge , Malena Ortegón Twiggy , Correa Cuadros Gustavo
Published: March 2022

Objetivo: Analizar el reporte de cuatro casos de suicidios, publicados en un diario de circulación masiva en la Costa Atlántica colombiana.

Métodos: Se llevó a cabo una revisión exhaustiva de las primeras cuatro noticias del año publicadas sobre casos de suicidio en 2012, en El Heraldo. Las notas periodísticas fueron tomadas del archivo histórico del Departamento del Atlántico y fotografiadas para su lectura y análisis por parte de los investigadores y contrastadas con las recomendaciones de la Organización Mundial de la Salud frente al suicidio en medios de comunicación.

Resultados y discusión: Ninguno de los cuatro artículos cumple con las recomendaciones de la Organización Mundial de la Salud. Todos informan sobre datos personales de los occisos y se brindan detalles que podrían impulsar a otras personas a cometer suicidio. Las notas periodísticas se acompañan de material fotográfico que aporta sensacionalismo y en ningún caso promueven la salud mental ni la prevención del suicidio.

Conclusiones: El manejo dado a los casos de suicidio dista mucho de un ideal en el que se debe promover la prevención del suicidio en lugar de magnificar los casos ocurridos a través de detalles que no aportan a la salud mental de la comunidad.
A Distasteful Milieu: Brian O’Nolan and the Civil Service, 1935–51
Authors: Maguire Martin
Published: March 2022

This article examines what Brian O’Nolan described as the ‘distasteful’ milieu of the civil service, contextualising O’Nolan’s career as a civil servant that paralleled his career as a writer. The civil service and officialdom are a growing presence in his writings, especially in Cruiskeen Lawn where Myles na gCopaleen speaks on behalf of the increasingly bitter civil servant, Brian O’Nolan.
İbn Arafa'nin Hayatı ve Eserleri
Authors: ALSHIBLY Obayda
Published: March 2022

Bu çalışma, İbn Arafe’nin hayatının tanıtılmasını hedeflemektedir. O, sekizinci asırda Arap Mağribi’nde, Tunus’ta, Hafsîler devrinde yaşamış bir tefsir yazarı ve meşhur bir âlimdir. İbn Arafe’nin kişiliği ilim ve eğitime adanmıştır. Hafsîler devrinde hüküm süren ekonomik, siyasî ve sosyal şartlardan etkilenen şahsiyeti değil, ilmî kişiliği, zamanının diğer kültürel ve bilimsel yönlerini etkilemiştir. O dönemde birçok öğrenci onun bol ilminden, birçok faydalı makalesinden ve dilsel görüşlerinden yararlandı; iyi bir çevrede ve erdemli bir ailede yetişmesi, onun ilmî kişiliğinin şekillenmesinde büyük ve önemli bir rol oynamıştır. O, babasından, âlimlerden, hukukçulardan, müfessirlerden ve dilcilerden çok şey almıştır. Ayrıca takvası, ilim ve âlimlere bağlılığı, ilim ve fazilet öğretmesi ve yayması ile halk arasında tanınmıştır. Böylelikle Arap Mağribi’nin meşhur isimlerinden birisi olmuştur.
SPORDA PSİKOLOJİK İHTİYAÇLAR DURUMU ÖLÇEĞİ (SPİDÖ): TÜRKÇE UYARLAMASI, GEÇERLİK VE GÜVENİRLİK ÇALIŞMASI
Authors: ÜNVER Şaban , YILMAZ Metin , ATAN Tülin , ÇANKAYA Soner , SAVUCU Yüksel
Published: March 2022

İnsan motivasyonunun anlaşılması doğuştan gelen psikolojik ihtiyaçların dikkate alınması gerekliliğini ortaya çıkarmaktadır. Bu çalışmanın amacı, Bhavsar ve ark. (2020) tarafından geliştirilen “Sporda Psikolojik İhtiyaçlar Durumu Ölçeği’ni (SPİDÖ) Türkçe’ye uyarlamak ve sporcularda geçerliliğini ve güvenirliğini test etmektir. Araştırmanın evrenini farklı spor branşlarında 14-26 yaş aralığındaki aktif sporcular, örneklemini ise tesadüfi örnekleme yöntemi ile seçilmiş ve araştırmaya gönüllü olarak katılmayı kabul etmiş 169 sporcu oluşturmaktadır. Türkçe’ye uyarlanan Sporda Psikolojik İhtiyaçlar Durumu Ölçeği 7’li likert tipinde, 23 madde ve 6 alt boyuttan (Özerklik memnuniyeti, Özerklik memnuniyetsizliği”, Yeterlilik memnuniyeti, “Yeterlilik memnuniyetsizliği”, “Aidiyet memnuniyeti, Aidiyet memnuniyetsizliği) oluşmaktadır. Ölçeğin yapı geçerliği için Doğrulayıcı Faktör Analizi ve güvenirliğini sınamak için Cronbach alfa iç tutarlık ve CR katsayısı kullanılmıştır. Doğrulayıcı Faktör Analizi sonuçlarına göre ölçekte yer alan maddelerin faktör yükleri 0,43-0,86 arasında değişmektedir. Elde edilen analiz sonuçlarına göre modelin iyi uyum indeks değerlerine sahip olduğu görülmüştür.Ki-kare uyum testi χ²/Sd=1,976, Yaklaşık Hataların Ortalama Karekökü=0,079, Normlaştırılmış Uyum İndeksi=0,90, Normlaştırılmamış Uyum İndeksi=0,95, Karşılaştırmalı Uyum İndeksi=0,95, Uyum İyiliği İndeksi=0,92, Düzeltilmiş Uyum İyiliği İndeksi=0,86 olarak saptanmıştır. Ölçeğin alt boyutlarına ait Cronbach alfa iç tutarlık ve CR katsayıları (0,64-0,84) kabul edilebilir değerlerdedir. Elde edilen bulgular “Sporda Psikolojik İhtiyaçlar Durumu Ölçeğinin” Türkçe uyarlamasının sporda psikolojik ihtiyaçların değerlendirilmesi için geçerlik ve güvenirlik koşullarını sağladığını ortaya koymaktadır. Sonuç olarak Sporda Psikolojik İhtiyaçlar Durumu Ölçeğinin güvenilir ve geçerli bir ölçüm aracı olduğu söylenebilir. Türk sporcularının psikolojik ihtiyaçlarını merak eden ve ölçmek isteyen araştırmacılara veya antrenörlere ölçeği kullanmaları tavsiye edilebilir.
Athletic Fundraising: An In-depth Analysis of the Challenges Faced and Strategies Utilized in the NCAA Division II Athletic Landscape
Authors: Hanson Andrew , Jon Welty Peachey
Published: March 2022

In the current economic environment, state appropriations to higher education are continually decreasing, with cuts in state aid resulting in universities undergoing significant financial cuts (Mitchell et al., 2017). In particular, National Collegiate Athletic Association (NCAA) Division II athletic departments have been seriously impacted. The Division II structure requires athletic programs to depend on private, charitable contributions, brought in through organized fundraising activities. This study used the previous athletic fundraising literature and stakeholder theory (Freeman, 1984) to guide 14 semi-structured interviews with Division II athletic fundraisers, representing a wide range of universities. The purpose of this exploratory study was to identify the major challenges that individuals who fundraise for Division II athletic departments face as well as the strategies that are being used to overcome those challenges. This study also aimed to identify the role that stakeholders played in athletic fundraising and how stakeholder claims of power, urgency, and legitimacy guided the fundraising process (Mitchell et al., 1997). Theoretical and practical implications are also advanced.
Identification and Verification of the Ferroptosis- and Pyroptosis-Associated Prognostic Signature for low-grade Glioma
Authors: Wang Jie , Ren Jie , Liu Jifeng , Zhang Linyun , Yuan Qihang , Dong Bin
Published: March 2022

Accumulating evidence reveals that ferroptosis and pyroptosis play pivotal roles in tumorigenesis of low-grade glioma (LGG). In this research, we aimed to classify molecular subtypes and further identify and verify a novel multigene signature in LGG on the basis of ferroptosis and pyroptosis-related genes (FPRGs). Raw sequencing data and corresponding clinical data of LGG samples retrieved from the TCGA and CGGA databases were obtained for the training and validation datasets. Non-negative matrix factorization (NMF) clustering defined by FPRGs associated with prognosis was performed to classify molecular subtypes of LGG patients. LASSO-SVM-Random Forest analysis was carried out to develop an FPRG signature to predict the survival and benefit of immunotherapy of LGG patients. NMF clustering defined by FPRGs with prognostic values acted to categorize LGG patients into two molecular subtypes with different prognosis, clinical traits and immune microenvironments. A six-FPRG prognostic signature was constructed, accompanied by the optimal p-value. The AUC values of our signature exhibited great prognostic performances. Our signature was superior to other four well-recognized signatures in predicting the survival probability of LGG patients. Immune characteristics, tumor mutation profile, tumor stemness indices, MGMT methylation and immunotherapy response biomarkers showed significant differences between high- and low-risk populations. Finally, a nomogram was created for quantitative prediction of the survival probability of LGG patients, with the AUC values of the nomogram being 0.916, 0.888 and 0.836 for 1-, 3- and 5-year survival, sequentially. Overall, the FPRG signature may function as an effective indicator for the prognosis prediction and immunotherapy response of LGG patients.
Разработка количественного опроса в прикладных городских исследованиях
Authors: Воробьева Ольга Владимировна
Published: March 2022

В статье рассмотрена методология создания опросника как части комплексного прикладного исследования городской среды, нацеленного на благоустройство определенной территории. Опросник рассматривается как вторая, количественная часть такого исследования, которая разрабатывается на основе качественной полевой работы с применением антропологических методов — включенного наблюдения на заданной территории, блиц-интервью с посетителями территории и глубинных интервью с экспертами (сотрудниками администрации, краеведами, активистами и др.), интервью-прогулок, ментальных карт. Представленный вариант опросника составлен на основе ряда предпроектных исследований, проведенных в 2019–2020 годах Центром компетенций по развитию городской среды и умному городу Ленинградской области, с учетом выявленной продуктивности вопросов вплоть до конкретных формулировок.

Предлагаемый опросник состоит из четырех последовательных блоков. Первый блок посвящен самоотчетам респондентов об актуальных сценариях использования территории (время и регулярность посещения, способы добраться до территории, субъективная безопасность и другие актуальные параметры). Второй — пожеланиям горожан относительно будущего благоустройства (желаемые функции, объекты и услуги). Третий — идентичности горожан, локальным нарративам и символическому пространству города (давность проживания семьи в городе, ассоциативные эксперименты относительно образа города и структуры городских объектов, каркас достопримечательностей, вернакулярная история города). Четвертый — расширенным социально-демографическим характеристикам, релевантным для понимания социального ландшафта города в контексте возможных стратегий использования физической городской среды (возраст и количество детей, принадлежность к городским сообществам, тип занятости и, как следствие, возможности для использования среды). Помимо получения количественных данных этот опросник также может использоваться для выявления некоторых качественных аспектов в ситуации невозможности полноценной полевой работы — как, например, в ситуации эпидемиологических ограничений 2020–2021 годов. Совокупные данные качественного и количественного этапов положены в основу разработки проекта благоустройства и востребованы как архитекторами и проектировщиками, так и самими горожанами на мероприятиях по соучаствующему проектированию и иным типам вовлечения жителей в благоустройство городской среды.
Соучаствующее проектирование устойчивого городского будущего: как вовлечь молодых взрослых?
Authors: Виноградова Ирина Анатольевна , Иванова Елена Владимировна , Барсукова Екатерина Михайловна
Published: March 2022

Городская среда становится мощным мотиватором территориальной мобильности горожан, в первую очередь молодых взрослых. Совместное проектирование становится одним из условий развития города и саморазвития горожан, которое выражается в возможности молодых взрослых самостоятельно реализовывать свои замыслы и проживать в комфортном городском пространстве. Это приводит к необходимости поиска эффективных способов вовлечения этой возрастной категории горожан в решение вопросов развития городской среды и устойчивого городского будущего. В статье предпринята попытка выявления и обоснования эффективных механизмов, форм и способов соучаствующего проектирования молодыми взрослыми городского будущего. Эти компоненты описаны на материале собственной практики соучаствующего проектирования, в том числе участия в проекте City Transformers, опыта работы с молодыми взрослыми Москвы и Красноярска. В качестве основных механизмов такого проектирования молодыми взрослыми устойчивого городского будущего следует рассматривать: построение коммуникативной среды, сетевое взаимодействие и стратегическое планирование. Эффективными способами погружения молодых взрослых в вопросы устойчивого городского будущего могут стать: решение кейсов, фокус-групповое интервью, проектные семинары, мастерские, коммуникационные игры и проведение исследований. Представленный в работе материал может стать основой для разработки концепции осознанного участия молодых взрослых в проектировании и развитии города, а также технологии соучаствующего проектирования в контексте устойчивого городского будущего с участием молодых горожан.
Умный город и гражданское участие
Authors: Вагин Владимир Владимирович , Сафронова Вера Денисовна
Published: March 2022

Умный город — одно из наиболее популярных понятий, используемых учеными и практиками для описания урбанистического будущего. Оно интересует все больше людей по всему миру. Об этой теме говорят сейчас все — от технологических гигантов Google и IBM, которые запускают проекты по превращению целых районов в умные пространства, до политических партий в разных странах мира. Большинство рассматривают умный город как городскую среду, где передовые технологии используются для решения социальных и экологических проблем. В исследовании и практике умных городов есть определенные проблемы. Одна из них состоит в том, что умные города упускают важность широкого спектра институционально оформленных процедур участия граждан в городском развитии и управлении различными частями городской жизни. За рубежом накоплен значительный опыт гражданского вовлечения. Более того, большинство европейских партий включили в свои программные положения участие граждан в городских процессах. Серьезное внимание современных западных ученых и политиков привлекает вопрос об общественном контроле за огромным массивом персональных данных, накапливаемом созданными ресурсами. К сожалению, в российской литературе нечасто вспоминают об этом аспекте умного города, безусловно затрагивающем интересы большинства горожан. При этом в Российской Федерации параллельно развиваются различные практики вовлечения граждан в процессы государственного и муниципального управления: создание комфортной городской среды, инициативное бюджетирование, онлайн-платформы городского участия. Данная статья собрала множество материалов по теме участия граждан из передовых зарубежных публикаций и предоставляет их краткий обзор. Во-первых, здесь описываются и сравниваются основные концепции и практики умного города. Во-вторых, внимание уделяется тому, как городские власти, научные организации и партии теоритизируют и реализуют проекты умных городов. Цель данной статьи — познакомить с основными концептуальными подходами в теории умного города, а также практиками участия политических партий и граждан в формировании умных городов малоизученной сферой урбанистического развития.
La homoparentalidad: un modelo más de unión familiar
Authors: Bartolomé Cantalejo María Yolanda
Published: March 2022

Las familias homoparentales constituyen una realidad cada vez más presente en las sociedades avanzadas; este tipo de unión familiar se afianza en nuestra comunidad diversa compuesta de múltiples nacionalidades, razas, culturas, creencias y por lo tanto de muchas opciones de constituirse en familia, ya que no existe un modelo único y válido de modelo familiar, bien por lazos afectivos o bien por lazos de sangre se puede constituir un núcleo familiar independientemente del sexo de la pareja: podemos hablar de familias heterosexuales, monoparentales, reconstituidas, y también familias homoparentales, todas ellas con conflictos que es preciso solventar; por eso, vamos a abordar un modo de resolver las situaciones de disensión en unas relaciones familiares con una composición distinta a la entendida como “familia tradicional” y cómo buscar una solución consensuada a las dificultades que se pueden crear en su entorno.

La mediación es uno de los métodos idóneos que pueden utilizarse en las relaciones conflictivas, adecuada para la gestión de conflictos familiares; de ahí la utilidad de la mediación familiar en la resolución de los conflictos en familias homoparentales.
Selección y comentario de resoluciones del orden jurisdiccional Contencioso-Administrativo. Tribunal Superior de Justicia de Extremadura. Año 2021
Authors: Villalba Lava Mercenario
Published: March 2022

Se ha llevado a cabo una selección de las resoluciones judiciales más representativas y relevantes dictadas por el Tribunal Superior de Justicia de Extremadura durante el año natural 2021. Dichas resoluciones corresponden al orden jurisdiccional Contencioso-Administrativo. Estas sentencias seleccionadas han sido objeto de comentario, dentro del contexto jurídico que las ha generado, por un destacado magistrado especializado en dicho orden jurisdiccional.
Real Cédula de Carlos III sobre bigamia y competencias de los tribunales
Authors: Habela Vaca Emiliana
Published: March 2022

Breve estudio que pretende dar a conocer un documento de la etapa del monarca español Carlos III (1759-1788) referente a las penas establecidas para aquellos que se casan dos o mas veces, viviendo su primera mujer, así como que estas causas deben ser resueltas por la Jurisdicción Real Ordinaria y no por el Tribunal de la Inquisición. El documento analizado es una copia enviada al Ayuntamiento de Badajoz para su cumplimiento en la ciudad y en todos los pueblos de su partido.
Transgenic Bt maize in South-and Central America: the pros and cons
Authors: Zenner-de-Polanía Ingeborg
Published: March 2022

The official authorization for planting Bt maize in most Central and South American countries was granted more than 20 years ago. This permission has raised concerns, has revealed inconsistencies in the information provided for farmers, has shown unknowns, motivating comments, and produced publications, often not scientific. Given the theoretical impact on environment, economy, and health, and the development of fall army worm´s resistance, despite the existing research capacity in these countries, the scientific literature is scarce, probably due to lack of funding and influence by the holders of the patents and the producers and traders of seeds of transgenic maize. The aim of this review is to debate the benefits and disadvantages originated by the sowing of the maize hybrids that contain any of the different Cry´s of the bacteria Bacillus thuringiensis. The documents reviewed do not elucidate conclusions; it will be necessary to wait years to define if the transgenic maize plantings represented a benefit for the growers and consumers of this plant species, which originated in these areas. However, at this moment an existing balance between the benefits and the risks of Bt maize plantings could be deduced.
Characterization of soil moisture dynamics in Colombian agricultural areas
Authors: Hernández-Guzmán Francisco Javier , Cleves-Leguizamo José-Alejandro , Díaz-Almanza Eliecer David
Published: March 2022

Seasonal dynamics in edaphic humidity are influenced by different environmental factors, such as topography, physical and chemical soil conditions, type of vegetation cover and climatic classification. Data from 105 agrometeorological stations in the IDEAM network, distributed throughout Colombia, with records from January, 2001 to April, 2020, were studied. A non-parametric Spearman rank correlation test was used to evaluate the relationship between soil moisture and atmospheric variables. Simultaneously, the behaviors of seasonal dynamics were analyzed, along with their interaction with atmospheric, physical soil and vegetation cover variables. The results showed that soil moisture is more significantly influenced by frequency than by intensity of precipitation; this variable had a seasonal behavior, similar to that of precipitation. The physical variable texture was closely related to the behavior of the soil surface moisture (<10 cm deep). In addition, there was evidence of a surface moisture response to the physical conditions of the soil, topography and availability of plant cover. As the soil depth increased, the soil moisture had less variation because the influence of the atmospheric conditions was greater on the surface and persisted longer over time.
Cálculo del tiempo térmico para 13 códigos de la escala BBCH de 12 progenies de quinua en las condiciones de crecimiento de la Sabana Brasileña
Authors: Anchico-Jojoa Wilson , Peixoto José Ricardo , Spehar Carlos Roberto , Vilela Michelle Souza
Published: March 2022

La introducción de la quinua (Chenopodium quinoa Willd.) en la Sabana Brasileña ha tenido éxito basada en la selección de progenies de los tipos de valle. Dada la amplia variación de ambientes, una alternativa para definir el ciclo de madurez de la planta ha sido el uso del tiempo térmico acumulado (TTA). Esta medida permite la predicción del ciclo de la planta y proporciona apoyo para definir la duración de la fenología, siendo útil en el manejo y mejoramiento de los cultivos. Este estudio tuvo como objetivo calcular las unidades térmicas para 13 códigos de la escala BBCH de la quinua, mediante la evaluación de 12 progenies seleccionadas y cultivadas en dos fechas de siembra, a 15° 56' S y 47° 55' O, altitud de 1.100 m, Brasilia, DF, Brasil. Las diferencias estadísticas fueron predominantes desde el inicio de las fases reproductivas BBCH-50, clasificando las progenies como precoces, de ciclo medio y tardías. Las progenies de madurez temprana y sus respectivas TTA para BBCH-89 son BRQ4 (1.676,8), BRQ1 (1.685) y AUR (1.691), contrastando con las tardías BLA (2.239), BRQ3 (1.929,1 GDD) y BRQ8 (1.895). Las unidades térmicas acumuladas para BBCH-89 oscilaron entre 1.565,25 y 2.381, con una diferencia entre los genotipos más precoces y los más tardíos de 815,75. Las progenies seleccionadas de los cultivares existentes son diferentes en cuanto a la acumulación de unidades térmicas, lo que implica la eficiencia en la adquisición de cultivares para escalonar el cultivo de quinua. Las unidades térmicas acumuladas explican el rango de ciclos de maduración de las plantas en la selección. Además, el cálculo del TTA para los códigos de la escala BBCH es una herramienta eficaz para predecir el ciclo fenológico de la quinua.
Symptoms and growth components of feijoa (Acca sellowiana [O. Berg] Burret) plants in response to the missing elements N, P, and K
Authors: Buitrago Sebastián , Leandro Manuel , Fischer Gerhard
Published: March 2022

Plants often express deficiencies with visible abnormalities; however, it is necessary to obtain reliable information to make the proper diagnosis about the missing nutrients. Until now, research with this approach has not been carried out for crops such as feijoa (or pineapple guava). For this reason, the present investigation identified and described the symptoms produced in young feijoa plants due to poor fertilization of N, P, and K and its effect on some components of plant growth and development. To achieve this, different treatments were established: complete fertilization (control); complete fertilization -N; complete fertilization -P; complete fertilization -K; and one treatment with no element (negative control, H2O). We determined the symptoms associated with each deficiency by means of a photographic record and the description of the symptoms. Among these nutrients, N deficiency yielded the highest plant detriment, due to lower growth and a global pale green coloration, while -P plants showed foliar malformations and necrosis, -K plants exhibited the brown margin in old leaves, then turning necrotic, while young leaves showed a lack of turgor. Also, lack of N seriously affected apical growth, number of basal and apical shoots, and chlorophyll foliar content, while the -P and -K developed lower growth rate in the shoot than in the control. Such symptoms were registered after two months of treatment. This study indicated that the greatest affectation of the feijoa was due to a lack of nitrogen; and also P and K deficiencies showed symptoms and growth characteristics that were altered in the development of the plants.
Infective endocarditis caused by gram-negative bacteria
Authors: Chipigina N. S. , Karpova N. Yu. , Kashentseva N. A. , Morits V.
Published: March 2022

Infective endocarditis (IE) caused by Gram-negative bacteria is a rare and insufficiently characterized form of endocarditis. The literature review presents data on the frequency, course, risk factors, diagnosis and treatment of both IE caused by the HACEK microorganisms (Haemophilus spр., Aggregatibacter spp., Cardiobacterium hominis, Eikenella corrodens, Kingella) and other Gram-negative bacteria. Gram-negative bacteria are the cause of 3.6–13.6 % IE cases (HACEK microorganisms in 0.8–3 % of IE cases in adults, non-HACEK in 1.8–3.9 %). Patients with IE caused by the HACEK microorganisms are younger, their disease is not associated with previous in-hospital treatment and is subacute with favorable prognosis (intrahospital mortality is 2–3 %). HACEK microorganisms mostly retain sensitivity to many antibiotics. Risk factors of IE caused by HACEK microorganisms are dental interventions, heart disorders, valve prostheses and other implanted cardiac devices. IE caused by non-HACEK Gram-negative bacteria is more common in elderly with concomitant disorders and usually is acute; intrahospital mortality is 13–36.5 %. Risk factors of IE caused by non-HACEK microorganisms are valve prostheses, electrical pacemakers, venous and central catheters, recent in-hospital treatment, Gram-negative bacteremia, decreased immunity, drug abuse, urinary infection, alcoholism, cirrhosis of the liver, removed spleen, consequences of dog and cat bites, working with the soil. Among Gram-negative non-HACEK bacteria causing IE, 28 % have multi-drug resistance (MDR / XDR) against antibiotics. Therefore, Gram-negative bacteria rarely cause IE but during selection of empiric therapy in patients with IE with corresponding risk factors, probability of Gram-negative causative microorganisms in IE etiology should be taken into account.
Pathology of the shoulder joint and soft tissues: clinical variants, current capabilities of pathogenesis-directed therapy
Authors: Shostak N. A. , Pravdyuk N. G. , Timofeev V. T. , Abeldyaev D. V.
Published: March 2022

Pain syndrome in the shoulder occurs in every 5th adult and is the 2nd most frequent reason for seeking primary medical care among all musculoskeletal disorders. Group of local causes of pain syndrome in the shoulder area. The starting point for differential search is patient’s age. For persons younger than 40, the most common causes are joint instability (dislocations / subluxations), as well as mild damage of the rotator cuff muscles due to injury. Patients older than 40 have an increased risk of severe chronic disorders of the above-mentioned muscles, adhesive capsulitis, and osteoarthritis of the shoulder joint. Treatment of shoulder joint and soft tissue pathology is nosological in nature and has to be justified by pathogenesis. Chondroreparants are a new class of pharmaceuticals based on hyaluronic acid modified by low molecular weight compounds using solid-phase stabilization. During physical stabilization (mechanosynthesis) of hyaluronic acid, chemical crosslinkers are not used, which leads to high tolerability and safety. Modified hyaluronic acid in Hyalrepair formulas has a number of structural features leading to its slower biodegradation in the tissues. Chondroreparant Hyalrepair-10 consists of hyaluronic acid, ascorbyl phosphate, zinc, cysteine, and glutathione; Hyalrepair- 2 consists of hyaluronic acid, ascorbyl phosphate, L-proline, L-lysine, and glycine. Use of intra-joint and periarticular injection of hyaluronic acid can be an effective approach in combination pathogenesis-directed therapy of the shoulder and soft tissues.
Analysis of A Tilting Table with Parallel Kinematics
Authors: Tüske István , Hegedűs György
Published: March 2022

This paper presents a workpiece moving unit with parallel kinematics, where its kinematic model is described. Based on the Chebyshev-Grübler-Kutzbach mobility equation the mobility properties of the mechanism are examined. Using the modified Chebyshev-Grübler-Kutzbach criterion the number of degrees of freedom of the workpiece tilting table is determined, after this the screw theory will be presented. As the Chebyshev-Grübler-Kutzbach criterion does not take into account the geometrical characteristics of the examined structure, using the screw theory the workpiece tilting unit will be reanalysed, to take geometrical characteristics into account in determining the degrees of freedom of the structure. Finally, the results of the two theories will be compared in the study of the given kinematic model.
Benefits of Cyber-Physical Systems Modeling and Simulation with LabView
Authors: Szász Csaba
Published: March 2022

Cyber-physical systems (CPSs) as part of the Industry 4.0 strategy, represents one of the most challenging research topic for engineers. It’s well known that CPSs integrate at highest level digital technology (computation, control and networking) into physical objects. However, by incorporating various heterogeneous subsystems with different energy levels and functionalities, both analogue and digital signals management, as well as a large scale of communication and information technologies, their modeling and simulation becomes a difficult engineering task. In the past years a huge number of research papers has been dedicated to identify and develop modeling techniques and simulation toolkits being able to handle CPSs complexity. Following these trends, this paper is focused to research and evidence issues linked with the LabView graphically oriented programming technology utilization for CPSs modelling and simulation purposes. Both advantages and shortcomings of this very special technology are studied in order to design and implement a viable software framework being able to model and simulate various CPS structures. As a concrete example, a specific CPS configuration consist of six computer-based mechatronic systems that constitute a laboratory-prototype manufacturing plant has been chosen for LabView-based modeling and simulation. Various virtual instrument-type models of this setup has been conceived and proposed for real-time simulation. It has been concluded then that the application of LabView technology lead to interesting and useful results. The paper specially highlights the benefits and versatility of LabView utilization for complex CPSs modeling and simulation purposes.
Performing Canny Edge Detection Using NI LabVIEW Software Environment
Authors: Geresi Zalan Tamas , Adila Afghan Syeda , Szemes Péter Tamás
Published: March 2022

Performing image acquisition and processing can require a high amount of computational resource. In this article, I am discussing the application of Canny Edge Detection algorithm to a live webcam image real-time using NI’s software environment.
Outcomes of Ahmed glaucoma valve implantation in pediatric glaucoma
Authors: Sadovnikova Natalia N. , Brzheskiy Vladimir V. , Prisich Natalia V. , Zertsalova Marina A. , Baranov Andrei Yu.
Published: March 2022

BACKGROUND: In many types of pediatric glaucoma, there is no clear algorithm for surgical management. In these situations, the procedure of choice can be the implantation of various types of drainage devices.
AIM: To evaluate the outcomes of Ahmed Glaucoma Valve implantation in refractory pediatric glaucoma.
MATERIALS AND METHODS: The treatment results of 52 children (67 eyes) aged 1 month 17 years (6.6 0.6 years) with unsuccessfully operated primary congenital glaucoma, with glaucoma associated with congenital anomalies of the eyeball, with secondary glaucoma were analyzed. The surgery was considered to be effective when stable intraocular pressure (IOP) was achieved, there were no complications, and no need for repeated interventions.
RESULTS: The effect of surgery was maintained for 6 months in 97% of patients, but after 1, 2 and 3 years it decreased to 91.8%, 82%, and 73.9%, respectively, and to 42.8% after 7 years. Postoperative complications included filtering bleb encapsulation (25.3%), iris retraction to the tube with pupil dislocation (4.5%); ciliochoroidal detachment (4.5%); cataract (3.0%), conjunctival erosion with tube eruption (4.5%), endophthalmitis (1.5%), retinal detachment (6.0%), tube retraction (1.5%), hyphema (3.0%). The risk factors for an unfavorable outcome of the procedure were: an increase in the anteroposterior axis of the eyeball length by 20% or more compared to the age norm, IOP at the time of the surgery higher than 32 mm Hg, as well as previous antiglaucoma filtering procedures.
CONCLUSIONS: The implantation of the drainage device Ahmed Glaucoma Valve is indicated for refractory pediatric glaucoma in case of ineffectiveness of previous surgeries. However, it is necessary to take into account the decrease in the effectiveness of the device over time, which, combined with the possibility of complications, requires long-term follow-up of patients.
Effect of Ficus carica (fig) seed oil administration on GSH levels, necrosis and cast formation in myoglobinuric acute kidney injury
Authors: İŞLER Derya , ŞİRİNYILDIZ Ferhat , EK Rauf Onur
Published: March 2022

Purpose: In this study, the effect of applying different doses of Ficus carica (fig) seed oil obtained by cold pressing method on the kidney tissue and serum GSH level, as well as the formation of necrosis and cast in the experimental myoglobinuric acute kidney injury animal model created with glycerol was investigated.

Materials and Methods: 32 Wistar albino male rats weighing 460-540 g were randomly divided into four groups of 8 each. Sham Control, MAKI, MAKI+FC3, MAKI+FC6. Urea and creatinine levels of the groups were analyzed by biochemical method. Tissue necrosis level was determined by histological analysis of kidney tissue sections.

Results: While urea and creatinine levels increased significantly in the MAKI group compared to all groups, they were found to be lower in the high and low dose treatment groups with no significant difference between them. Tissue and serum GSH levels in the MAKI group were significantly decreased compared to all groups. In the MAKI+FC3 and MAKI+FC6 groups, an increase was detected in the tissue without dose difference, and in the serum only with high dose. The highest score in kidney tissue cast and necrosis levels were observed in the MAKI group, while significant improvements were detected in the treatment groups.

Conclusion: Ficus carica(fig) seed oil, provided improvement in morphological damage with improvement in functional damage and increase in antioxidative capacity.
Kanserde Hedefe Yönelik Tedavi: PI3K/Akt/mTOR İnhibitörleri
Authors: KÜPELİ Serhan
Published: March 2022

Kanserler genel olarak çoklu genetik ve epigenetik anormallikler içermekte fakat birkaç anahtar gen sayesinde malign fenotip ve hücresel sağkalımın devamlılığı sağlanmaktadır. PI3K/Akt/mTOR yolağı önemli birçok fizyolojik olaylarda rol alan merkezi bir sinyal akım sistemidir. PI3K/Akt/mTOR yolağı birçok tümör çeşidi tarafından kullanıldığından bu yolağa karşı kullanılan inhibitörlerin geniş bir terapötik etkinliğinin olabileceği düşünülmektedir. Tekli tedavide bu inhibitörlerin hiçbiri ile faz 1 çalışmalarda önemli cevap oranları elde edilememiş olup yüksek dozların kısa sürelerde verilmesi ve değişik yolaklara etkili olabilecek ilaçların kombine edilmesi gibi diğer seçenekler araştırılmaktadır.
Yanık Nedeniyle Tedavi Gören Hastalarda Yenilikçi Teknoloji: Sanal Gerçeklik
Authors: KAYA Merve , KARAMAN ÖZLÜ Zeynep
Published: March 2022

Sanal gerçeklik son yıllarda sağlık bakım uygulamalarında özellikle yanık yaralanmalarında yaygın olarak kullanılan gelişmiş bir bilişsel teknik aracıdır. Ciddi ve çok yönlü bir yaralanma olan yanık yaralanmaları hastayı yalnızca fiziksel olarak değil psikolojik olarak da etkilemekte, hastalar bu durumun üstesinden gelme ve baş etme konusunda yardıma ihtiyaç duymaktadır. Yanık yaralanma sürecinin akut ve rehabilitasyon süreçlerinde ağrının giderilmesinde önemli bir non-farmakolojik analjezi yöntemi olarak sanal gerçekliğin etkisi kanıtlanmıştır. Aynı zamanda hastaların yaşadığı anksiyete, korku üzerinde de olumlu etkileri olduğu tespit edilmiştir. Sanal gerçekliğin yanık hastalarında yeniden epitelizasyon sürecini hızlandırdığı ve iyileşme sürecini desteklediği vurgulanmıştır. Bu çalışmanın amacı hemşirelik bakımı ve multidisipliner sağlık ekibi için potansiyel ve önemli bir teknoloji olarak kendini gösteren sanal gerçekliğin, yanık hastasının tedavisinde kullanımının ve etkilerinin değerlendirilmesidir.
Blurred vision and diplopia in full term vaginal delivery women
Authors:   Department of Endocrine Research Center, Laboratory of Endocrine in South China, Xu Hongmei
Published: March 2022

Pituitary apoplexy can be a life-threatening condition, which is not easily diagnosed or treated. Predisposing factors of pituitary apoplexy include bromocriptine treatment, head trauma, pregnancy, pituitary irradiation, anticoagulation. Apoplexy may occur during pregnancy with appropriately managed, visual symptoms often improve, but endocrinologic function may remain compromised. This case reported that 30-year-old female full term vaginal delivery after years of primary infertility presented in emergency department with headache and blurred vision and diplopia, CNS examination unremarkable except third cranial nerve palsy. In conclusion, pituitary apoplexy is a rare cause of sudden and severe attack of headache during pregnancy. A multidisciplinary team needs to reduce morbidity and mortality.
Stab wound to the heart with cardiac tamponade — A case report
Authors: Gajmer Pooja
Published: March 2022

The rising incidences of violence nowadays have lead to increased cases of shootings and stabbings being reported. And among the stabbing cases, one of the frequently encountered are penetrating injuries to the heart, which is a highly lethal condition. If not treated promptly, more often than not results in death of the victim. In the scenario that the victim reaches the hospital, a number of factors come into consideration, which have a direct bearing on the outcome, for example, the physiologic state of the victim, involvement of other organs, location of injury, cardiac tamponade, etc. Among these presence of cardiac tamponade is a critical prognostic factor. Various studies have shown that a slow hemorrhage is much better tolerated as it can be gradually accommodated by the pericardium but any acute rise in intrapericardial pressure lead to a fatal effect in cardiac function and death. This scenario is discussed in the case being reported below.
Herbicide poisoning assocaited methhemoglobinemia as a cause of hypoxia — approach & emergency management — A case report
Authors: Deshpande Sudhir , Gupta Sagar , Tupkary Yashawini , Sankpal Shivprasad
Published: March 2022

Methhemoglobinemia — is a altered form of hemoglobin which is associated with impaired O2 transport to body tissues, precipitate by deliberate ingestion of herbicide (larvicide). We report a case with severe methhemoglobinemia due to ingestion of herbicide containing biological extracts & fillers marketed as safe. This is suspected when there is low O2 saturation and disparity between SpO2 level & PaO2 level, timely managed with Methylene Blue & Ascorbic acid as antidote.
Sustainability Assessment of the Municipal Solid Waste Management in Russia Using the Decoupling Index
Authors: Starodubets Natalia V. , Belik Irina S. , Alikberova Tamila T.
Published: March 2022

The annual growth of the municipal solid waste (MSW) generated and the exhaustion of existing landfills capacity have led to the processes of reforming the waste sector in Russia. But the question remains open: what is the optimal ratio between waste management practices for building a sustainable MSW management system? The purpose of this article is to evaluate the sustainability of the MSW management system in Russia according to various scenarios of its development using the decoupling index. Based on the strategic documents, authors constructed three scenarios for the MSW industry development in Russia until 2024: scenario 1 (basic), scenario 2 (MSW utilization via recycling), scenario 3 (MSW utilization via recycling and MSW incineration at WTE plants). After that, the decoupling index for all scenarios was calculated. In general, calculations of the decoupling index for 2022-2024 showed that for all scenarios (except for scenario 3 in 2022), the industry is moving into the zone of absolute sustainability. The greatest sustainability is achieved in scenario 2 – for this scenario the absolute value of the decoupling index is maximum in 2023 and 2024, thereby confirming the role of recycling in increasing the sustainability of the MSW management system. The results can be used by decision makers when reforming the MSW management system to choose the optimal ratio between the MSW management practices and the appropriate regulatory tools.
Land Allocation Policies of National Housing Programs and Projects: Proposals and Implementation Mechanisms for Housing Lands in New Cities in Egypt
Authors: Al-Abbasy Hend , Eid Marwa
Published: March 2022

Egypt has been suffering from a significant housing problem of unbalanced housing provision for all segments of society. During the past decades, the state addressed this problem through successive land allocation and housing policies. However, those efforts were insufficient to resolve the issue, and there is still a gap between the demand and supply of adequate housing types for low-income groups. This paper, aims to come up with proposals Mechanisms for housing and land allocation policies in Egypt. The methodology of this research is based on monitoring and analyzing the development of land allocation and housing policies and programs from 1952 to 2020 to identify deficiencies in the different implementation mechanisms and their effectiveness. Also, three successful international experiences (Singapore, Australia and Morocco) representing various of housing land allocation policies are examined to identify essential lessons applicable in the Egyptian context. From the results of this analysis, and the outcome of structured interviews with Egyptian stakeholders in Housing field comprising housing academia and housing experts and planners. The paper finally proposes several institutional, legislative, planning, financial administrative and informational mechanisms to fulfill the land allocation policies and link them to the policies and programs of the national housing plans in Egypt.
Techniki językoznawstwa korpusowego wykorzystywane w krytycznej analizie dyskursu. Przegląd
Authors: Kamasa Victoria
Published: March 2022

Krytyczna analiza dyskursu (KAD) jako nurt z pogranicza socjologii i językoznawstwa skupia się na analizie roli dyskursu w umacnianiu i reprodukowaniu relacji władzy i dominacji, zaś badaniu empirycznemu podlegają przede wszystkim różnego rodzaju teksty. Właśnie koncentrację na tekście uznać można za jedną z przyczyn wzrastającego zainteresowania wykorzystaniem metod językoznawstwa korpusowego w takich analizach. Prezentacji tych metod poświęcony jest niniejszy artykuł. Przedstawione zostaną podstawowe strategie doboru korpusu do badań w ramach KAD oraz najczęściej wykorzystywane metody: analiza frekwencji, analiza słów kluczowych, analiza kolokacji i analiza konkordancji. Zaprezentowane zostaną także przykłady zastosowania poszczególnych metod w różnorodnych tematycznie badaniach. Przegląd metod podsumowany zostanie omówieniem korzyści wypływających z ich zastosowania oraz kosztów, które się z nimi wiążą.
Evernote: zastosowanie notatnika internetowego do badań jakościowych
Authors: Piszek Artur , Stachura Krzysztof
Published: March 2022

W artykule przedstawiono aplikację Evernote jako prostą i darmową alternatywę dla profesjonalnych pakietów przeznaczonych do jakościowej analizy danych, przy jednoczesnym wskazaniu ograniczeń opisywanego narzędzia. Wymieniono funkcje przydatne badaczowi do zastosowań analitycznych oraz wskazano techniki pozwalające na aplikację metodologii teorii ugruntowanej przy pomocy tego programu. Wskazano także podobieństwa i różnice pomiędzy Evernote a pakietem NVivo 10 oraz nakreślono nowe perspektywy analityczne na najbliższą przyszłość związane z rozwojem Evernote.