bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of splitting direction for coupling WGM resonators
Authors: Wang Jianwei , Sun Jiapeng , Song Yeshuai , Yang Xulong , Zhang Yu , Liu Zhihai , Li Hanyang
Published: September 2024

The opposite splitting directions of mode splitting are observed in whispering gallery mode resonators, composed of coupling asymmetrical bispheres. A "virtual ellipsoid" model approximates the bispherical structure, linking the observed optical phenomena in bispheres to those in ellipsoids. The splitting characteristics are investigated theoretically and experimentally, including intensity difference and wavelength separation. The splitting direction is determined by the positions of the fundamental mode and azimuthal mode in the splitting peaks. Experimental results reveal that the resonant wavelength of the splitting peaks exhibits a redshift due to the increased diameter of Sphere D2, which is attributed to longer light propagation paths in the whispering gallery mode. The optical barcodes converted from transmission spectra provides potential applications for measuring the sizes of microspheres or ellipsoids, and their uniqueness can also be utilized for optical information identification.
Effect of Smartphone Addiction on Hand Disorder, Eye Health, Fatıgue and Cognitive Failures
Authors: ÖZALP Muhammet
Published: September 2024

Background: As mobile phones have become essential in daily life, concerns have arisen about their overuse and the emergence of mobile phone addiction. Research indicates that excessive mobile phone use can contribute to a variety of health problems, including cognitive impairments, visual disturbances, hand discomfort, and fatigue. This study investigated the impact of mobile phone addiction on various health parameters, including cognitive status, eye health, hand discomfort, and fatigue, among university students. A total of 293 students participated in the study. Methods: Students mobile phone addiction status was assessed via the Smartphone Addiction Scale-Short Version (SAS-SV). The students were divided into two groups according to the cutoff values given in the study: the "addicted group(n:142) (SAS-SV value man>31, woman>33)", consisting of those determined to have mobile phone addiction, and the "control group (n:151)", consisting of those nonaddictive tendencies. The Chalder Fatigue Scale for fatigue evaluation, the Cognitive Failures Questionnaire for cognitive status, the Cornell Hand Discomfort Questionnaire for hand discomfort, and the Ocular Surface Disease Index for eye dryness were used. Data were collected online via Google Forms following ethics committee approval. Results: The addicted group presented higher scores on the Cognitive Failures Questionnaire, indicating poorer cognitive performance(p<0.001). Additionally, significant differences were observed in fatigue levels (p=0.014), and eye health(p=0.002). Notably, hand discomfort was significant in specific zones of the right hand (p<0,05). However, no significant differences were found in other regions of the hand(p>0,05). Conclusions:These findings underscore the adverse health effects associated with mobile phone addiction, highlighting the need for awareness and potential interventions among university students.
Prevalence and associated factors of anemia among women of childbearing age in the eastern region of Burkina Faso
Authors: OUEDRAOGO Ousmane , COMPAORE Ella W. R. , OUEDRAOGO Ousmane , KIBURENTE Mediatrice , DICKO Mamoudou H.
Published: September 2024

Background: In Burkina Faso, anemia is a serious public health problem, with a prevalence well above the 40% threshold. We need to identify the factors associated with it in order to combat this scourge effectively.
Objective: The objective of this study is to identify associated factors of anemia among women of childbearing age in the eastern region of Burkina Faso.
Method: This was a cross-sectional descriptive and analytical study. A validated and digitized questionnaire on the ODK data collection application was used to collect data from women of childbearing age in households by means of individual interviews. The ‘hemocue’ rapid diagnostic test was used to measure the level of hemoglobin in the blood of 614 women aged 15 to 49 years. The cutoff point for any anemia was a hemoglobin level of less than 11.0 g / dL in pregnant women and 12.0 g/dL in non-pregnant women. The chi-square test was used for bivariate analyzes and logistic regression for multivariate analyzes using the SPSS software.
Results:
The results show that 71.8% of women (pregnant or not) were anemic. The age and marital status of women and the use of iron/folic acid supplements had a statistically significant association with anemia in women of childbearing age. In fact, women living alone (single, divorced or widowed) are 5 times more likely (OR=5,155; CI=1,821-14,593; P=0,002) to be anemic than married women.
Individual and household characteristics must be taken into account when designing policies and plans to address anemia.
Smartphone use, health-promoting behaviours and self-rated health among middle-aged and elderly people in rural areas
Authors: Gan Xiaomin , Liu Xuefang , Wu Juan
Published: September 2024

Objective
Accounting for the convergence of digitalization and ageing, our study focused on middle-aged and elderly people in rural areas. Moreover, the potential mechanisms by which smartphone use affects the self-rated health and heterogeneity among different groups were explored, and the mediating effects of health-promoting behaviours were explored, with the aim of providing relevant insights and recommendations for improving the health of rural middle-aged and elderly people and actively promoting healthy ageing in rural areas.
Methods
On the basis of data from the 2020 China Rural Revitalization Survey, we established a multiple linear regression model to assess the direct effects of smartphone use (including whether to use, difficulty of use, and duration of use) on the self-rated health of rural middle-aged and elderly people and examined the heterogeneity among the various groups in terms of sex, age, and education level. In addition, the three-step regression and bootstrap test methods were used to analyse the mediating effect of health-promoting behaviours on the relationship between smartphone use and self-rated health.
Results
Smartphone use among rural middle-aged and elderly people significantly and positively affected their health-promoting behaviours and self-rated health, and the findings were robust. The positive effects of smartphone use on self-rated health were heterogeneous among rural middle-aged and older adults of different ages, sexes, and education levels. Health-promoting behaviours exerted significant mediating effects, accounting for 91.91%, 95.27% and 90.91% of the total effects, respectively.
Conclusion
Smartphone use among rural middle-aged and elderly people notably affected the improvement in their self-rated health, and this positive effect differed according to sex, age and education level. The indirect path of encouraging rural middle-aged and elderly people to use smartphones, reducing the difficulty of smartphone use, and prolonging the duration of smartphone use for enhancing health-promoting behaviours could effectively improve their self-rated health.
The Hippo effector TEAD1 regulates murine cerebellar development
Authors: Atterton Cooper , Pelenyi Alexandra , Jones Justin , Al-Khalily Majd , Wright Lucinda , Doonan Mikki , Knight David , Kurniawan Nyoman D. , Walters Shaun , Thor Stefan , Piper Michael
Published: September 2024

The Hippo signalling cascade is an evolutionarily conserved pathway critical for the development of numerous organ systems and is required for the development of many parts of the mammalian nervous system, including the cerebellum. The Hippo pathway converges, via the nuclear YAP/TAZ co-transcription factors, on transcription factors of the TEA Domain (TEAD) family (TEAD1-4) and promotes the expression of pro-proliferative genes. Despite the importance of TEAD function, our understanding of spatial and temporal expression of this family is limited, as is our understanding of which TEAD family members regulate Hippo-dependent organ development. Here, we focus on TEAD1 and how this factor contributes to postnatal murine cerebellar development. We find expression of TEAD1 within cerebellar progenitor cells and glial cells, including astrocytes and Bergmann glia, as well as by some interneurons within the granular layer. The importance of TEAD1 expression for cerebellar development was investigated using a conditional ablation approach, which revealed a range of developmental deficits in these Tead1 mutants, including an underdeveloped cerebellum, morphological defects in Bergmann Glia and Purkinje Neurons, as well as granule neuron migration defects. Collectively, these findings suggest a major role for TEAD1 as an effector of the Hippo pathway during cerebellar development.
Free vibration properties of novel sandwich plates with a Layered and Rotational Core
Authors: Wang Youlong , Cai Yuxiang , Hosen Kamal , Pan Junwei
Published: September 2024

The layered sandwich plate structure is widely used in various fields due to its lightweight and high-strength characteristics. To further enhance the functionality of these structures and expand their application areas, this study investigates the impact of an innovative method for adjusting the interlayer angle, using honeycomb and grid cores as examples. The effect of this interlayer angle on the first nine natural frequencies and vibration modes of the sandwich plates is explored. The results indicate that 1) at different angles, the natural frequencies of the same order vibration modes exhibit significant differences. For instance, in the case of the grid core, the minimum change rate of the natural frequency can exceed 10%, and the maximum can reach 16.68%; 2) compared to the unadjusted layered plates, which exhibit localized deformation in higher-order vibration modes, the stiffness distribution becomes more uniform after rotation, transforming the vibration modes into overall continuous deformations; 3) the proposed method allows for considerable changes in natural frequencies of various orders while maintaining stable structural mechanical properties without adding weight. This effectively avoids resonance with the working environment and promotes uniform stiffness distribution, making the structure suitable for use in more demanding stable environments.
Geophysical Characterization of Subsurface Suitability for Infrastructure at Ayat Real Estate Foundation, Addis Ababa
Authors: Misganaw Tewodros , Haile Tigistu , Yehualaw Esubalew , Wassihun Simeneh
Published: September 2024

This study provides a detailed geophysical assessment of subsurface conditions at the Ayat Real Estate site in northeastern Addis Ababa, employing electrical resistivity tomography (ERT), vertical electrical sounding (VES), and seismic refraction methods. Data from four VES points, dipole‒dipole ERT lines, and seismic refraction profiles reveal nearly vertical fractures and weak zones oriented NW–SE, which could impact foundation design, with competent hard formations suitable for construction located at depths of up to 12 m. The findings show increasing resistivity and P-wave velocity with depth, indicating progressively stronger subsurface materials, whereas low resistivity at shallow depths highlights physically weak zones. The subsurface consists of four layers: highly plastic clay with low resistivity (3.03–25 Ω-m) and P-wave velocities (< 0.42 km/s); a middle layer with moderate resistivity (30–42 Ω-m) and P-wave velocities (< 1.79 km/s); higher resistivity bedrock (38–65 Ω-m) with P-wave velocities (< 2.4 km/s); and a deeper, slightly weathered bedrock layer with resistivities of 86–206 Ω-m. Structural features and fractures indicate potential saturation or weathering. These findings highlight the need for drainage, compaction, and stabilization to manage soil expansion and geohazards. Geophysical data combined with borehole information confirm the site's suitability for multistory construction and provide key insights for foundation design.
A two-decade bibliometric review of climate resilience in agriculture using the dimensions platform
Authors: Chimi Pierre Marie , Fobane Jean Louis , Matick John Hermann , Mala William Armand
Published: September 2024

Climate resilience in agriculture is crucial for addressing climate change challenges. This bibliometric review, using the Dimensions platform, analyzes research trends, international collaborations, and key areas from 2004 to 2024. It identifies 477 sources contributing to 1,000 documents, with a 25.77% annual growth rate and an average of 10.15 citations per document, involving 2,605 authors. The thematic map highlights the central role of “climate change” and its links to “resilience,” “policy,” and “sustainable development,” advocating for an integrated approach to climate issues. The annual publication trend shows a significant increase in interest, with a strong positive correlation (R² = 0.7097) and linear growth, emphasizing adaptive strategies. Leading journals include “Qeios Ltd,” “Handbook of Climate Change Resilience,” and “Sustainability.” Key terms like “Climate Change” and “Adaptation” have grown substantially, reflecting the evolving discourse. The co-authorship network reveals three main clusters, led by researchers such as David D. Woods, Andrea Nowak, and David Zilberman. Influential publications, highlighted by their Local Citation Scores, showcase both global and local impacts. The historical citation network and word cloud visualization emphasize the interconnectedness of key concepts, illustrating the collaborative and cumulative nature of research in this field. This review provides a comprehensive overview, guiding future studies, informing policy, and fostering collaboration to enhance climate resilience in agriculture. By leveraging these insights, policymakers can develop more effective, evidence-based strategies, ultimately contributing to sustainable development and food security. Future research can build on these findings to create more effective and sustainable solutions.
Graph Neural Networks-Based Dynamic Water Quality State Estimation in Water Distribution Networks
Authors: Salem Aly K. , Taha Ahmad F. , Abokifa Ahmed A.
Published: September 2024

The substantial cost associated with deploying and operating sensor networks challenges the pursuit of comprehensive water quality (WQ) management in drinking water distribution networks (WDNs). In this study, we introduce a framework for dynamic WQ state estimation using Graph Neural Networks (GNNs) to reconstruct unmeasured chlorine concentrations (CCs) based on measurements from a limited number of distributed sensors. Two GNN frameworks were developed. In the first framework, the model was trained to conduct Static Prediction (SP) of CCs based on data collected from a specific sensor placement configuration. In the second framework, a GNN model was trained using data from various sensor placement configurations to produce a generalized state estimation model capable of conducting Dynamic Prediction (DP). That is, reconstructing CCs throughout the WDN based on data collected from any sensor placement configuration, even if different from those used in its training. The two models were applied to a benchmark, real-life WDN, with a sensor coverage of only 3%. The results of the two models highlighted their ability to produce accurate predictions for intermediate junctions, while struggling to predict CCs at dead-end junctions. The SP model outperformed the DP model in terms of accuracy, and its predictions showed significant robustness against noisy measurements. On the other hand, the DP model stood out for its flexibility in being applicable to different sensor network designs. Furthermore, the DP model accuracy was found to be highly dependent on the input sensor design, highlighting the potential for its implementation within sensor placement optimization frameworks.
Magnesite formation during nesquehonite decomposition in the presence and absence of retained self-generated gases and the role of X-ray amorphous materials as essential stores for CO2
Authors: Morgan Bree , Wilson Sasha , Madsen Ian C. , Gozukara Yesim M. , Kimpton Justin A. , Maynard-Casely Helen E.
Published: September 2024

Long-term storage of CO2 in nesquehonite (MgCO3·3H2O) relies on its transformation to highly stable magnesite (MgCO3) in a naturally occurring, centuries-long process. Here, we pair in situ X-ray diffraction and thermogravimetric analysis to investigate the thermal transformation (30–650°C, 5°C/min) of nesquehonite to magnesite, under both open and closed experimental conditions, in a supplied atmosphere of CO2 or N2, and in the presence or absence of self-generated gases (i.e., CO2, water vapor). We found that following the structural collapse of nesquehonite, magnesite only forms in the presence of gaseous CO2 (and in a closed system in the presence of water vapor), whether that be externally supplied or self-generated. This is consistent with a dehydration-crystallization mechanism, with increased local accumulation of CO2 (and in a closed system, H2O vapor) shifting thermal events to higher temperatures, allowing for the crystallization of magnesite. Approximately 20 wt% more magnesite formed when nesquehonite was flushed with CO2 gas during heating in an open system, rather than held within a closed, static CO2 atmosphere. We hypothesize that this difference is due to complete dehydration being more difficult to achieve in a closed system, delaying crystallization of magnesite. Additionally, the distribution of passivating reaction products on unreacted mineral cores may occur in closed systems, where self-generated humidity is retained, and the dissolution-precipitation of reaction products may occur at mineral surfaces. We also find that amorphous materials are dominant intermediate stores for CO2, which is significant given they are not typically considered during carbon accounting in natural landscapes or engineered settings. We proposed a novel method to accurately quantify amorphous solids from XRD data during in situ studies where significant gas loss occurs. Our findings further our mechanistic understanding of how magnesite forms from crystalline and amorphous precursors under a range of environmental and industrial conditions, which is key to optimizing stable CO2 storage in Mg-carbonate minerals. In particular it highlights the importance of considering the role of amorphous phases, atmospheric composition and self-generated gas retention during magnesite formation.
PERFIL DA PEQUENA E MÉDIA EMPRESA DO RAMO CALÇADISTA: UM ESTUDO DE CASOS MÚLTIPLOS EM JUAZEIRO DO NORTE (CE)
Authors: Sousa Carlos Antônio Ferreira de , Paiva Maria Jeanne Gonzaga de
Published: September 2024

Este estudo tem como objetivo traçar o perfil da pequena e média empresa do ramo calçadista em Juazeiro do Norte (CE) no ano de 2002. Rezalizado através de pesquisa bibliográfica e de campo, cujo tamanho das empresas foi estabelecido pelo critério Sebrae e as informações cadastrais junto ao Sindidústria. Sendo, acess´-ivel uma amostragem a 75% das médias e 50% das pequenas. Dos principais resultados, tem-se que, apenas, as médias concentram vendas nas regiões Sul/Sudeste e só uma exporta. Em relação à mão-de-obra, 75% dos gerentes têm ensino médio e apenas 25% com nível superior, nenhumas das entrevistadas dispõem de ISO (padrão internacional de qualidade). Dos problemas citados, encontra-se, a acrência de tecnologia. Já as estratégias apontadas foram: atendimento das necessidades dos clientes e garantia de prazos de entrega. Conclui-se que, as referidas empresas apresentaram defasagens tecnológicas e somente as médias apresentaram uma melhor estrutura organizacional e produtiva.
IMPACTO DA GLOBALIZAÇÃO E O TURISMO
Authors: Soares Eliziar Maciel
Published: September 2024

Ensaio criado em torno do tema globalização e turismo, que objetiva mostrar que com a globalização dos mercados, ocorreu também a globalização do turismo. O turismo aproveitou de forma mercado lógica o que estas novas fronteiras têm a apresentar, procurando fazer de forma eficiente sua prestação de serviços, criando novas modalidades, se qualificando, tornando-se profissional, se promovendo como uma das atividades econômicas mais promissoras e alternativas deste milênio
PÓS-MODERNISMO: UMA RUPTURA OU CONTINUIDADE DO MODERNISMO?
Authors: Souza Reginaldo Adriano de , Costa Mônica Oliveira , Ventura Rita de Cássia Martins de Oliveira
Published: September 2024

Este artigo buscou informações sobre as teorias administrativas, bem como uma leve apresentação de suas evoluções no passar dos anos. Frente às grandes mudanças da atualidade buscou-se compreender as idéias modernistas e também entender do que se trata o modernismo. Dentro do modernismo localizou-se a Escola Clássica como sendo o principal foco do momento, onde houve uma racionalização, especialização e normatização nas formas de trabalho. Os autores pós modernos criticam essa postura exagerada de desvalorização do ser humano, que era considerado como uma continuação da máquina. No entanto, verificou-se a grande dificuldade de se entender o pós-modernismo, alguns autores consideram uma ruptura do modernismo, enquanto outros consideram uma evolução apenas. Outra dificuldade está em se projetar as características dessa nova época, uma vez que ainda se encontra em construção. Existe ainda uma fragmentação da figura humana em decorrência da diversidade, da flexibilidade e da relatividade em que se encontra o mundo atual.
A HISTÓRIA ORAL E A ENTREVISTA
Authors: Oliveira Adriana Patrícia de , Hot Amanda Dutra , Campos Germano Moreira , Moreira Leonard Maulaz dos Santos
Published: September 2024

A entrevista é a principal ferramenta de trabalho da História Oral. É por meio dela que são constituídos os documentos orais, sendo eles essenciais para a produção de pesquisas voltadas para a chamada “história vista de baixo”. O campo da História Oral é um dos mais recentes, dentro da historiografia contemporânea, o que faz com que desperte algumas dúvidas e incredulidades da parte dos historiadores mais tradicionais. Há ainda outros problemas que são colocados, como a invenção do depoimento, visto que esse, por mais conciso e imparcial que pareça, é fruto de uma visão individual a respeito de determinado fato. O presente artigo busca analisar a temática da produção de entrevistas para a História Oral, destacando as negociações, as dificuldades e as vantagens das fontes orais para a ciência histórica atual.
Investigating the Cytotoxic, Apoptotic, Treatment-Resistant, and Inflammatory Response Properties of a Gold(III) Complex Containing a Tetradentate Schiff Base Ligand
Authors: Zhang Xiaoling , Wei Ke , Heidari Majd Mostafa , Shahraki Somaye , Zhao Xiaojuan
Published: September 2024

Considering the cytotoxic properties of Schiff base ligands, we re-synthesized a gold(III) complex with a tetradentate Schiff base ligand and investigated its cytotoxic effects using the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) method and sulforhodamine B staining method. The results showed that the gold(III) Schiff base complex can inhibit the growth of Chinese hamster ovary (CHO) cancer cell lines. However, unlike cisplatin, it does not induce cell death in NIH 3T3 normal cells. Real-time polymerase chain reaction (PCR) results revealed that the gold(III) Schiff base complex increased the Bak1/Bclx ratio in CHO cell line by 3.53-fold compared to the control, while cisplatin increased the anti-apoptotic Bclx gene by 31.8 times and the treatment resistance AKT1 gene by 430.8 times the control. However, cisplatin only activated the extrinsic pathway of apoptosis through the caspase-3 gene. The expression levels of TLR6 and TNF-α genes in normal cells showed that both the gold(III) Schiff base complex and cisplatin did not cause inflammation in NIH 3T3 cell lines. All the results indicate that the new complex could be a promising candidate to replace cisplatin. It has been shown that it induces apoptosis and prevents the development of resistance in cancer cells. Additionally, it does not cause inflammation in normal cells.
The Multitarget Action of Vitamins in the Ischemic Stroke
Authors: Scotti Luciana , da Silva Pablo Rayff , Monteiro Alex France M. , de Araújo Rodrigo Santos  Aquino , do Nascimento Vanessa Lima , Monteiro Kadja Luana Chagas , de Aquino Thiago Mendonça , dos Santos Silva Wadja Feitosa , da Silva Junior Edeildo Ferreira , Scotti Marcus T. , Mendonça Junior Francisco Jaime Bezerra
Published: September 2024

:

A stroke, also known as a cerebral hemorrhage, occurs when there is an interruption in
the blood supply to a part of the brain, resulting in damage to brain cells. This issue is one of the
leading causes of death in developed countries, currently killing about 5 million people annually.
Individuals who survive ischemic stroke often face serious vision problems, paralysis, dementia,
and other sequelae. The numerous efforts to prevent and/or treat stroke sequelae seem insufficient,
which is concerning given the increasing global elderly population and the well-known association
between aging and stroke risk. In this review, we aim to present and discuss the importance of
vitamins in stroke prevention and/or incidence. Vitamins from diet or dietary supplements influence
the body at various levels; they are a relevant factor but are reported only in isolated articles.
This review reports and updates the multitarget role of vitamins involved in reducing stroke risk.
Trifolirhizin from Sophora flavescens as a Promising Medicinal Agent: An Update on Biological Significance, Pharmacological Activity, and Analytical Applications
Authors: Patel Kanika , Patel Dinesh Kumar
Published: September 2024

Sophora flavescens is an important medicinal plant found in India and East Asia,
primarily in China, Japan, Korea and Russia. Trifolirhizin is an active phytochemical of Sophora
flavescens and other Chinese medications such as Zeng-Sheng-Ping, Xian-Lian-Ke-Li, ASHMI,
Ling Zhi, Ku Shen, and Gan Cao, Ku Shen injection and Zeng Sheng Ping tablets. Sophora
flavescens have numerous therapeutic benefits against hematochezia, jaundice, liver disorders,
dysentery, oliguria, asthma, eczema, vulvar swelling, and inflammatory complications. The
purpose of the present review is to summarize the scientific information on trifolirhizin for their
biological potential, pharmacological activities, and analytical aspects. Scientific information on
trifolirhizin has been collected from various scientific databases such as Scopus, Science Direct,
PubMed, and Google Scholar. Further, the present review summarized the pharmacological
activities of trifolirhizin and their different molecular mechanisms and analytical aspects. The
scientific data on trifolirhizin signified the biological potential and therapeutic effectiveness of
trifolirhizin in medicine. Present review signified the presence of trifolirhizin in the Sophora
flavescens. Sophora flavescens has been shown to be effective against ulcers, chronic bronchitis,
acne, atopic dermatitis, chronic hepatitis, enteritis, pyogenic infection and other inflammatory
diseases. Furthermore, the present review also summarized the biological potential of
trifolirhizin in gastric cancer, hepatocellular carcinoma, colorectal cancer, apoptosis, ulcerative
colitis, and asthma. However, hepatoprotective effects, anti-inflammatory effects, wound healing
potential, and efficiency of melanin synthesis were also revealed. In addition, this review also
summarizes the molecular mechanisms of trifolirhizin and their pharmacokinetic and metabolic
parameters. This review also describes the analytical aspects of trifolirhizin in medicine. This
review will be useful to the entire research community exploring the biological potential of
trifolirhizin in medicine. However, scientific studies require comprehensive and detailed data on
trifolirhizin evaluation, quality control, toxicity, and clinical efficacy.
Labial Pigmented Lesions
Authors: Murgia Martina Salvatorina , Orrù Germano , Casu Cinzia
Published: September 2024

The diagnosis of oral mucosal pigmentations is complex, and
histopathological evaluation may be necessary to clarify the nature of the lesion.
Although most oral pigmented lesions are benign, it must be emphasized that
melanoma of the oral cavity, probably the most aggressive epithelial tumor, is often
underestimated and diagnosed late. The dentist, therefore, should have basic knowledge
of the main epidemiological and clinical characteristics of this large group of lesions.
Pigmented lesions associated with melanin include racial pigmentations, melanotic
macules, smoking-associated melanosis, melanocytic nevi, melanoacanthoma, and
melanoma. Some systemic diseases (for example, Peutz-Jeghers syndrome and
Laugier-Hunziker syndrome) are also characterized by the presence of melanin lesions
in the oral mucosa. In the literature, there are also some cases of pigmentation caused
by melanin in association with the intake of drugs and as a consequence of some postinflammatory mechanisms. Pigmented lesions not associated with melanin are
subdivided according to the nature of the pigment responsible for the discoloration. The
pigmentations caused by the deposition of exogenous pigments are represented by
some metals (for example, amalgam, tattoo), drugs, or their metabolites.
Evolution of Evidence-based Practices in Counseling Psychology
Authors: Khan Anwar , Madihie Amalia bt , Khan Rehman Ullah
Published: September 2024

Problem Domain: Understanding the historical evolution of evidence-based psychotherapy is crucial for contextualizing its current practices and future directions. This chapter delves into the rich history and evolutionary journey of evidence-based approaches within the realm of Counseling Psychology, shedding light on its origins, development, and global perspectives. Goal of this Chapter: The second chapter aims to provide a comprehensive overview of the evolution of evidence-based psychotherapy, tracing its historical roots and contextualizing its emergence within counseling psychology. By exploring topics such as the history of evidence-based practice, the foundations of counseling psychology preceding its advent, the timeline of evidence-based practice, and the progress achieved in evidence-based practice across Asia, this chapter aims to acquaint readers with the historical context of evidence-based psychotherapies.Selling Points and Contributions of this Chapter: By offering insights into the evolution and historical context of evidence-based approaches, this chapter provides readers with a deeper understanding of the underpinnings and influences shaping contemporary practices in Counseling Psychology. To be more precise, the following are the areas where this chapter has significantly contributed:i) This chapter offers a detailed exploration of the historical context surrounding evidence-based psychotherapies, including the origins of evidence-based practice and its integration into Counseling Psychology.ii) By tracing the timeline of evidence-based practice and highlighting key milestones, this chapter provides a comprehensive overview of its evolution, from inception to present-day practices.iii) In addition to examining the evolution of evidence-based practice in Western contexts, this chapter explores its progress and adoption in Asia, particularly Pakistan, offering insights into cross-cultural variations and implications. iv) Through the exploration of historical and cultural factors, this chapter contextualizes the development of evidence-based psychotherapies, enriching readers' understanding of its diverse influences and trajectories.Short Results: By acquainting readers with the historical context of evidence-based psychotherapies and their evolution within Counseling Psychology, this chapter lays the groundwork for further exploration and reflection on the past, present, and future of evidence-based practices in psychotherapy.
Status of Evidence-based Mental Healthcare Counseling System in Pakistan
Authors: Khan Anwar , Madihie Amalia bt , Khan Rehman Ullah
Published: September 2024

Problem Domain: This chapter discusses the challenges and gaps in the evidencebased mental healthcare counseling system in Pakistan. Despite growing recognition of
mental healthcare in the country, significant hurdles impede the effective provision of
evidence-based psychotherapies and counseling services. These obstacles include
limited resources, inadequate infrastructure, and cultural stigmatization surrounding
mental health, which collectively hinder access to quality mental healthcare
interventions for Pakistani individuals. Furthermore, there is a notable lack of
awareness and understanding of evidence-based practices among mental health
professionals and policymakers, exacerbating the disparities in mental healthcare
access and quality across the country.
Goal of this Chapter: The sixth chapter specifically focuses on discussing the
important aspects of evidence-based mental healthcare counseling systems and the
effectiveness of evidence-based psychotherapies in Pakistan. By providing insights into
the complex dynamics of the Pakistani mental healthcare system, this chapter aims to
educate readers on the challenges and opportunities in improving mental healthcare
delivery in the country.
Selling Points and Contributions of this Chapter: This chapter offers a comprehensive
overview of the status of evidence-based mental healthcare counseling systems in
Pakistan, highlighting the need for enhanced resources, infrastructure, and awareness to
address the growing mental health needs of the population. By shedding light on the
effectiveness of evidence-based psychotherapies in the Pakistani context, this chapter
serves as a valuable resource for policymakers, healthcare providers, and researchers
seeking to improve mental healthcare outcomes in the country. More specifically, this
chapter has made a substantial contribution in the following ways:i) This chapter assesses the current status of evidence-based mental healthcare
counseling systems in Pakistan, identifying key challenges and opportunities for
improvement.ii) By evaluating the effectiveness of evidence-based psychotherapies in the Pakistani
context, this chapter provides insights into the applicability and relevance of these
interventions in addressing mental health issues in the country.iii) The chapter offers recommendations for enhancing the effectiveness and
accessibility of evidence-based mental healthcare counseling systems in Pakistan,
including strategies for increasing awareness, building capacity, and improving
infrastructure.
Short Results: In summary, this chapter serves as a crucial resource for understanding
the status of evidence-based mental healthcare counseling systems in Pakistan. By
identifying key challenges and opportunities, and offering recommendations for
improvement, this chapter contributes to ongoing efforts to strengthen mental
healthcare delivery and improve outcomes for individuals with mental health issues in
Pakistan.
Cultural Adaptation of Evidence-Based Psychotherapies for Common Mental Health Disorders in Pakistan
Authors: Khan Anwar , Madihie Amalia bt , Khan Rehman Ullah
Published: September 2024

Cultural Adaptation of Evidence-Based Psychotherapies for Common Mental Health Disorders in Pakistan offers a comprehensive overview of practical psychotherapy in a Pakistani cultural context. The authors aim to bridge knowledge gaps for practitioners who may be familiar with conventional methodologies and want to understand the subject from a regional perspective. The content includes seven meticulously written and referenced chapters that start with an overview of evidence-based therapy, progressing to modern psychotherapy techniques. The book concludes with information intended to guide the reader to adapt psychotherapy practices in Pakistani cultural settings.

Key Features

· Provides an introductory overview of evidence-based psychotherapy

· Provides an overview of psychotherapy practice in Pakistan

· Covers advanced technologies used in psychotherapy like Eye Movement Desensitization and Reprocessing, and Cognitive Behavioral Therapy to effectively address conditions such as post-traumatic stress disorder, depression, and anxiety

· Suggests culturally sensitive methodologies for practitioners working in Pakistani communities

This book is an ideal reference for clinical psychology researchers, psychotherapists, mental health counselors, academicians, and students. The insights in the book are invaluable, not only for Pakistani readers but also for those across Asia, providing a comprehensive blueprint for culturally adapting psychotherapies to diverse contexts.
Faktor Yang Menentukan Sikap dan Pengaruhnya Terhadap Minat Keperilakuan Dalam Menggunakan E-Commerce
Authors: Lestari Della Puspita , Baridwan Zaki
Published: September 2024

This study aims to examine the factors affecting the attitude and behavioural intention to use e-commerce platforms, utilizing the Modification of the Technology Acceptance Model (TAM). The data of this study are collected through a survey of 220 respondents Accounting Department students of the Faculty of Economics and Business, Universitas Brawijaya. The Partial Least Square (PLS) analysis results revealed that perceived ease of use, perceived usefulness, perceived risk, and trust affected the attitude, and the attitude affected the behaviour intention. The implications of this study are relevant for e-commerce developers as they may consider the factors affecting an individual intention to use an e-commerce platform in developing information systems.
Abstrak 
Studi ini bertujuan untuk menguji faktor-faktor yang mempengaruhi sikap penggunaan terhadap minat keperilakuan individu dalam menggunakan e- commerce. Studi ini menggunakan model Modifikasi Technology Acceptance Model (TAM). Studi ini menggunakan metode survei dan mengambil sampel dari Mahasiswa Akuntansi Fakultas Ekonomi dan Bisnis sebanyak 220 responden. Studi ini menggunakan Partial Least Square (PLS) untuk menguji data penelitian. Hasil studi ini adalah konstruk persepsi kemudahan penggunaan, persepsi kegunaan, persepsi risiko, dan kepercayaan berpengaruh terhadap sikap. Selanjutnya sikap penggunaan berpengaruh terhadap minat keperilakuan dalam menggunakan e- commerce. Implikasi studi ini adalah relevan bagi pihak e-commerce untuk dapat mengembangkan sistem informasi dengan memperhatikan faktor-faktor yang mempengaruhi minat individu dalam menggunakan e-commerce.
Analisis Cost Volume Profit (CVP) Sebagai Alat Perencanaan Laba Pada Usaha Onotaki Dalam Situasi Ekonomi Masa Pandemi Covid-19
Authors: Allegheno Ditoananto  , Purwanti Lilik
Published: September 2024

The unstable Indonesian economy due to the COVID-19 pandemic crisis has led to changing conditions and increasingly complex business competition. Every business must have good management or business planning to manage its resources efficiently and effectively. This study aims to determine the implementation of Cost Volume Profit (CVP) analysis as a profit planning tool in Micro, Small, and Medium Enterprises (MSMEs). The object of this research is OnoTaki, which is one of the SMEs in the Japanese culinary specialties. This research uses a case study descriptive approach. The primary data sources used in this study are sales and purchase data. The results of the study indicate that the OnoTaki business in 2021 is above the Break Even Point, and good business management with a Margin of Safety indicates that business conditions are not in danger. The profit target for 2022 is Rp. 24,000,000.-. With the help of CVP analysis, unit sales must be achieved by 6,050 units by maintaining price, product quality, and service to consumers in order to add outlets.
Abstrak
Perekonomian Indonesia yang tidak stabil akibat krisis pandemi COVID-19 menyebabkan perubahan kondisi dan persaingan bisnis yang semakin kompleks. Setiap usaha harus memiliki manajemen atau perencanaan usaha yang baik dalam mengelola sumber daya yang dimiliki secara efisien dan efektif. Penelitian ini bertujuan untuk mengetahui implmentasi analisis Cost Volume Profit (CVP) sebagai alat perencanaan laba pada Usaha Mikro Kecil Menengah (UMKM). Objek penelitian ini adalah OnoTaki yang merupakan salah satu UMKM di bidang kuliner khas Jepang. Penelitian ini menggunakan metode deskriptif pendekatan studi kasus. Sumber data yang digunakan dalam penelitian ini berupa data primer yang berisi data penjualan dan data pembelian. Hasil penelitian tersebut menunjukkan bahwa usaha OnoTaki pada tahun 2021 berada di atas Break Even Point dan pengelolaan usaha cukup baik dengan Margin of Safety menunjukkan kondisi usaha tidak dalam bahaya. Target laba untuk tahun 2022 adalah sebesar Rp 24.000.000,-. Dengan bantuan analisis CVP, maka penjualan unit yang harus dicapai adalah sebesar 6.050 unit dengan tetap mempertahankan harga, kualitas produk, pelayanan kepada konsumen agar dapat menambah gerai.
Pengaruh Profitabilitas dan Good Corporate Governance Terhadap Pengungkapan Corporate Social Responsibility
Authors: Ivan Mario  , T. Sutrisno
Published: September 2024

This study quantitatively analyzes the effect of profitability and good corporate governance on corporate social responsibility disclosure. The population of this study includes all companies listed on the Indonesia Stock Exchange (IDX) in 2020, from which the samples were selected through purposive sampling. This study includes 223 data of financial reports, annual reports, and sustainability reports acquired from the official websites of respective companies. Hypothesis testing is conducted by using descriptive statistical analysis, classical assumption tests, and multiple linear regression analyses. The results of the study indicate that the increase in managerial ownership and institutional ownership has a positive effect on corporate social responsibility disclosure. Meanwhile, corporate social responsibility disclosure is not affected by profitability and independent commissioners.
Abstrak
Tujuan penelitian ini adalah untuk menganalisis pengaruh profitabilitas dan good corporate governance terhadap pengungkapan tanggung jawab sosial perusahaan. Populasi dari penelitian ini adalah seluruh perusahaan yang terdaftar di Bursa Efek Indonesia (BEI) tahun 2020. Penelitian ini menggunakan metode penelitian kuantitatif dengan teknik pengambilan sampel purposive sampling. Sampel penelitian yang digunakan berjumlah 223 data. Sumber data yang digunakan dalam penelitian ini berasal dari laporan keuangan, laporan tahunan, dan laporan keberlanjutan yang diperoleh melalui website resmi setiap perusahaan yang terdaftar di BEI tahun 2020. Pengujian hipotesis dilakukan dengan menggunakan metode analisis statistik deskriptif, uji asumsi klasik dan analisis regresi linier berganda. Hasil penelitian menunjukkan bahwa peningkatan pada kepemilikan manajerial dan kepemilikan institusional memiliki pengaruh positif terhadap pengungkapan tanggung jawab sosial perusahaan. Sementara itu, pengungkapan tanggung jawab sosial tidak dipengaruhi oleh profitabilitas dan komisaris independen.
Effect of Working Capital and Intellectual Capital on Profitability
Authors: Widyasari Hani Sekar , Novianti Nurlita
Published: September 2024

This study aims to examine the impact of working capital and intellectual capital on profitability in the consumer goods industry from 2016-2021, listed on the Indonesia Stock Exchange. This type of research is quantitative explanatory research. This study uses purposive sampling and multiple linear regression with the SPSS model version 26. There are 14 selected industries from 52 consumer goods industries from 2016-2021. The researchers use secondary data, namely the financial statements contained on the Indonesia Stock Exchange and the annual report of each company's website. The findings show that, from 2016 until 2021, working capital and intellectual capital had a positive impact on profitability. This shows that companies that are able to utilize their working capital well and optimize their intellectual capital will be able to increase profitability.
Abstrak
Tujuan penelitian ini untuk mengetahui pengaruh working capital dan intellectual capital terhadap profitabilitas pada perusahaan consumer goods tahun 2016-2021 yang terdaftar di Bursa Efek Indonesia. Jenis penelitian ini adalah penelitian explanatory kuantitatif. Penelitian ini menggunakan teknik purposive sampling dan regresi linear berganda dengan model SPSS versi 26. Terdapat 14 perusahaan terpilih dari 52 perusahaan sektor konsumsi daro 2016-2021. Peneliti menggunakan data sekunder yaitu laporan keuangan yang terdapat pada Bursa Efek Indonesia dan annual report setiap website perusahaan. Hasil penelitian menunjukkan bahawa selama 2016 sampai 2021, modal kerja dan modal intelektual memiliki pengaruh yang positif terhadap profitabilitas perusahaan. Hal ini menunjukkan perusahaan yang mampu memanfaatkan modal kerjanya dengan baik dan mengoptimalkan intelektual capitalnya akan mampu meningkatkan profitabilitas
Pengaruh Mekanisme GCG dan Kualitas Audit Terhadap Manajemen Laba (Studi Empiris pada Perusahaan Non-Keuangan yang Terdaftar di Bursa Efek Indonesia Tahun 2013-2018)
Authors: Sinaga Judith H Melinda , Mardiati Endang
Published: September 2024

This study aims to determine and examine the effect of Good Corporate Governance mechanisms—including institutional ownership, managerial ownership, independent commissioners and audit committees—and audit quality on the earnings management of non-financial companies. The population in this study included all companies listed on the Indonesia Stock Exchange from 2013 to 2018, in which the samples of 100 companies were selected through purposive sampling based on the sampling criteria, resulting in 600 observed data during 6 years. The data were analysed by multiple regression, and the result indicated that the Good Corporate Governance mechanism and audit quality did not affect earnings management, implying that Good Corporate Governance mechanism and audit quality were not capable of preventing earnings management from occurring in a company.
Abstract:
Penelitian ini bertujuan untuk mengetahui pengaruh mekanisme Good Corporate Governance yang terdiri dari kepemilikan institusional, kepemilikan manajerial, komisaris independen dan komite audit terhadap manajemen laba di perusahaan non-keuangan. Penelitian ini juga menguji pengaruh kualitas audit terhadap manajemen laba di perusahaan non-keuangan. Populasi dalam penelitian ini merupakan seluruh perusahaan yang terdaftar di Bursa Efek Indonesia dari tahun 2013 sampai dengan 2018. Metode sampling dalam penelitian ini adalah purposive sampling. Berdasarkan kriteria-kriteria pengambilan sampel yang telah ditetapkan selama tahun 2013 hingga 2018 diperoleh sebanyak 100 perusahaan. Dengan menggunakan metode penggabungan data selama pengamatan 6 tahun tersebut diperoleh sebanyak 100 x 6 periode atau diperoleh sebanyak 600 data amatan. Teknik analisis yang digunakan adalah regresi berganda. Hasil analisis mengarahkan peneliti kepada kesimpulan bahwa mekanisme Good Corporate Governance dan kualitas audit tidak memiliki keterkaitan dengan manajemen laba. Kesimpulan ini mengindikasi bahwa mekanisme Good Corporate Governance dan kualitas audit belum bisa mencegah terjadinya manajemen laba dalam suatu perusahaan.