bluuebunny/crossref_metadata_2025 huggingface dataset:
Burocracia o autogestión: Manejo de pequeños sistemas de agua potable en cinco municipios hidalguenses
Authors: Galindo Escamilla Emmanuel ,   Universidad Autónoma del Estado de Hidalgo
Published: December 2021

En 1934 el gobierno federal mexicano inició una política de salud pública con el objetivo de modernizar el abasto de agua para uso doméstico en las zonas rurales, para lo cual se introdujo el sistema de tubería en red, y los beneficiados fueron los pequeños centros de población con menos de 2,500 habitantes que no constituyeran cabeceras municipales. Las dependencias que ejecutaron tal política entre 1934 y 1980 fueron: el Departamento de Salubridad,después Secretaría de Salubridad y Asistencia; el Departamento de Asuntos Indígenas, después Instituto Nacional Indigenista; el Departamento Agrario, después Secretaría de Agricultura; la Secretaría de Recursos Hidráulicos a través de su Rama de Ingeniería Sanitaria; y la Coordinación General del Plan Nacional de Zonas Deprimidas y Grupos Marginados, en coordinación con la Secretaría de Asentamientos Humanos y Obras Públicas. En dicho proceso llama la atención el hecho de que los sistemas de agua potable construidos por la Secretaría de Recursos Hidráulicos eran manejados por esta mediante las Juntas Federales de Agua Potable; pero una vez que recuperaba la inversión, los entregaba a los ayuntamientos. También llama la atención el caso de los sistemas construidos por la Secretaría de Salubridad y Asistencia, porque fueron entregados a los pueblos beneficiados, mismos que con diez usuarios conformaron las denominadas juntas rurales de agua potable, que tuvieron como atribuciones la administración, la operación, el mantenimiento y, en su caso, la ampliación del sistema en cuestión. Las regiones conocidas como Valle del Mezquital y Los Altos, en Hidalgo y Chiapas, respectivamente, representan casos en donde la Secretaría de Recursos Hidráulicos construyó y entregó sistemas de agua potable a los usuarios. En la primera, la infraestructura se instaló en cooperación con el Patrimonio Indígena del Valle del Mezquital y en la segunda, con el Instituto Nacional Indigenista.
Daire Simgesi Ve Kutsal Bağlantıları Üzerine: Manevi Temelde Aşkın Bir Üretim
Authors: ASLAN Yunus
Published: December 2021

Kutsal kavramı dini, sanatsal ve felsefi çerçeve içerisinde, hem doğrudan hem de yorumbilimsel olarak, oldukça farklı tanımlamalarla ifade edilmektedir. En genel tanımıyla kutsal; tapınılacak derecede önemsenen, üstüne titrenen, bozulmaması ve dokunulmaması gereken, dini bir saygı uyandıran Tanrısal-İlahi-Aşkın niteliğe denmektedir. Kutsallık veya kutsiyet atfetme genellikle insanı aşan, sonsuz, mutlak, değişmez olana, dolayısıyla aşkın olana (Yaratıcı-Tanrı) kesin bir bağlılıkla karşımıza çıkmaktadır. İnsan nesli, kavramaya çalıştığı aşkın niteliği, kutsalın tezahür araçlarından olan sanat ve semboller yoluyla yeryüzünde yansıtma çabasına girişmiştir. Konumuz çerçevesinde daire ve kutsal bağlantıları; kozmolojik, felsefi, sembolik, sanatsal, mitolojik ve mimari boyutlarıyla ele alınmıştır. Anlam noktasında insan zihninde bu iki unsurun, bağlantılı olarak gelişim gösterdiği, incelenen örnekler ve simgeler aracılığı ile anlaşılmaktadır. Eski çağlardan bu yana sürekli tekrarlanan, en eski işaretlerden birisi olan daire simgesi, kutsalın yeryüzündeki ilk yansıma ve temsillerinden birisidir. Bu çalışmada kutsal kavramı ve daire simgesi, bazı soyut ve somut örneklerle incelenerek, iki kavram arasındaki anlam bağlantısı sorgulanmıştır.
Making HIS More Agile, Relevant and Public Health Friendly: Lessons from Covid-19 in India
Authors: Sahay Sundeep , S Mukherjee Arunima , K Tauro Carolyn , Sen Arijit
Published: December 2021

Anthony Giddens, the noted sociologist, describes the COVID-19 pandemic as a ‘digidemic,’ emphasizing the inextricable linkages between the pandemic and the digital. As the pandemic has spread globally, countries have adopted different strategies to leverage digital technologies, in their design, development, implementation, and governance to address the pandemic. Some of these strategies have worked well and others have not so. We submitted this paper at the time when India was fighting the first COVID-19 wave and are submitting this revised version as India fights a much tougher second wave. And between these two waves, we have witnessed some flattening of the COVID-19 curve and the onset of a rigorous vaccination drive. This paper aims to try to analyse some experiences of how countries leveraged digital technologies in their information systems response, such as from Sri Lanka, South Korea and anchored in a historical understanding of public Health Information Systems (HIS) in India, build key learnings for strengthening HIS in India, both for pandemic situations and also routine health management. These include i) improving agility, reflecting the ability of the HIS to provide timely information for supporting local action; ii) improving relevance, implying providing required information for supporting the desired action for different stakeholders; and, iii) public friendliness, implying the HIS should help support population health at large in an equitable manner. We argue that these learnings are not only relevant for strengthening the HIS response to pandemic management but also more broadly for strengthening Indian public HIS covering routine systems. These learnings are particularly pertinent in the current ‘digital’ context in India, where large-scale interventions related to the National Digital Health Mission are currently being planned and implemented. For good or bad, the ‘digital’ is inevitable in public health systems globally, and it becomes important for researchers and practitioners to engage with this process of understanding the digital interventions and contribute to strengthening the health systems.
AWARENESS LEVEL OF LOCAL PEOPLE ON CULTURAL HERITAGE: THE CASE OF DİYARBAKIR
Authors: Emre DİLEK S. , BAL Fatime
Published: December 2021

Çalışmanın amacı, Diyarbakır’da bulunan somut ve somut olmayan kültürel miras unsurlarının turizm amaçlı olarak kullanılmasında yerel halkın farkındalık düzeyini belirleyebilmektir. Bu yönüyle de hem turizm paydaşlarına hem de turizm
literatürüne katkı sağlayacak olması bakımından önem arz etmektedir. Araştırma evrenini Diyarbakır merkez ilçelerinde yaşayan yerel halk oluşturmaktadır. Bu kapsamda nicel araştırma yöntemlerinden yararlanılmıştır. Kolayda örnekleme
yöntemi aracılığıyla ve yüz yüze anket tekniği ile analizlere dahil edilen toplan 200 veriye ulaşılmıştır. Elde edilen veriler SPSS programı ile analiz edilmiştir. Pandemi nedeni ile veri sayısı düşük kalsa da, analizler noktasında
istatistiki olarak herhangi bir sorunla karşılaşılmamıştır. Analiz sonuçlarına göre, araştırmaya katılan yerel halkın demografik özellikleri, Diyarbakır’ın turistik öneme sahip tarihsel ve kültürel yapıları, el sanatları, mutfağı,
etkinliklerine dair frekans analizi ve ortalamalarına yer verilirken, Anova testi ile yaş, farklı demografik gruplar arasında kültürel miras unsurlarına yönelik bir farklılık olup olmadığına bakılmıştır. Araştırma bulgularına göre
Diyarbakır yerel halkının kültürel miras unsurlarına yönelik farkındalık düzeylerinin düşük olduğu; yaş, medeni durum ve gelir grupları arasında farkılıklar bulunduğu söylenebilmektedir.
Enterocolitis inducida por proteínas alimentarias en un paciente con síndrome de pseudo-Bartter asociado a fibrosis quística. Reporte de un caso
Authors: Camargo-Vargas Bethy , Varela María , Wilches Laura , Martinez Quiñones María Paula , Acuña-Cordero Ranniery
Published: December 2021

Introducción: La enterocolitis inducida por proteínas alimentarias es una alergia alimentaria no mediada por inmunoglobulina E, manifestada en forma aguda por vómito recurrente, deshidratación y choque. Es una patología inusual que requiere alto índice de sospecha. El pseudo-Bartte (alcalosis metabólica, hipocaliemia e hipocloremia en ausencia de tubulopatía) es una complicación infrecuente de fibrosis quística.
Reporte de caso: Niño de cinco meses de edad con vómito recurrente, deshidratación y choque, alimentado con lactancia materna, pero que consumió fórmula tres horas previas al inicio de síntomas. Los exámenes de laboratorio confirmaron hiponatremia, alcalosis metabólica hipoclorémica e hipocalemia sin tubulopatía; dos iontoforesis mostraron resultados alterados; la elastasa en materia fecal se encontró disminuida y la secuenciación genética confirmó el diagnóstico de fibrosis quística. La prueba de provocación confirmó enterocolitis inducida por proteínas alimentarias.
Conclusión: El vómito recurrente y la deshidratación tras la ingesta de fórmula láctea deben hacer sospechar un enterocolitis inducida por proteínas alimentarias. Ante el hallazgo de pseudo-Bartter se debe descartar fibrosis quística.
Clinic, pathologic and molecular landscapes in ultra-young women with breast cancer in the State of São Paulo: a real-world study
Authors: Mattar André , Yoshimura Adriana Akemi , Fristachi Carlos Elias , Pessoa Eduardo Carvalho , Andrade Felipe Eduardo Martins , Tosello Giuliano , Vespoli Heloísa Maria de Luca , Carneiro Karina Belickas , Oliveira Idam de , Borges João Bosco Ramos , Filassi José Roberto , Gebrim Luiz Henrique , Piccinilli Marina Filie Haddad , Vieira René Aloisio Costa , Dassie Thamyse Fernanda de Sa , Tarriconi Vicente , Barros Alfredo Carlos Simões Dornellas de
Published: December 2021

Introduction: Breast cancer (BC) centers are increasingly attending “ultra-young” women (UYW) patients (≤ 30 years), who usually present aggressive tumors and face specific problems. Objectives: We aimed to examine a multicentric casuistic view, addressing clinicopathological and molecular characteristics of BC, as well as therapeutic measures and oncological outcomes. Methods: A retrospective multicentric observational study of UYW with infiltrating BC was carried out. The patients were treated between the period from January 1991 to December 2019. Clinical, epidemiological, morphological, molecular, therapeutic and outcomes data were collected from the charts. Results: A total of 293 patients were followed for a average period of 34.5 months. Nulliparity was referred by 204 women (75.5%), of whom 81 (37.1%) were overweight or obese. Positive family history in first-degree relatives was verified in 25 patients (10.1%). Only 30 patients underwent genetic tests, which revealed inherited pathogenic mutations in 12 of them (37.5%). Thirty-two (32) cases were classified as T1 at diagnosis (10.9%), while “De novo” stage IV was found in 29 patients (9.8%). Mastectomy was performed in 175 women (70.2%), quadrantectomy in 46 women (18.4%), and mammary adenectomies in 28 women (11.2%), of which 149 cases were reported after neoadjuvant chemotherapy (56.0%). A total of 111 patients had at least one positive lymph node (47.4%). The rate of patients with estrogen receptor-negative was 32.7% and the rate of patients with Human Epidermal Growth Factor Receptor 2-positive (HER2-positive) was 25%. The frequency of Luminal A neoplasias was 16.6%, Luminal B/HER2- was 35.9%, Luminal B/HER2+ was 15.1%, HER2 overexpressed was 9.3%, and Basal was 22.9%. Taking into account the outcomes, 173 patients were alive without disease (65.7%); 23 patients were alive with any form of recurrence (8.7%); and 67 patients (25.4%) evolved to BC deaths. Conclusions: It was concluded that UYW with BC are commonly diagnosed at advanced stages, present adverse morphological and molecular parameters, and have unfavorable prognosis.
Rendimiento y biomasa acumulada en frijol común bajo riego y secano
Authors: Romero Félix Celia Selene , López Castañeda Cándido , Kohashi Shibata Josué , Martínez Rueda Carlos Gustavo , Miranda Colín Salvador , Aguilar Rincón Víctor Heber
Published: December 2021

El frijol común (Phaseolus vulgaris L.) cultivado bajo condiciones de secano, se ve afectado por la sequía terminal, reduciendo de manera considerable el rendimiento de semilla y la biomasa acumulada en el dosel de la planta. El objetivo de este estudio fue evaluar la variabilidad en rendimiento de semilla, fenología y biomasa aérea acumulada durante la etapa reproductiva, en un grupo de variedades de frijol común, en condiciones de riego (R) y sequía (S), en el Colegio de Postgraduados, Campus Montecillo. Se utilizaron ocho genotipos de frijol tipo ‘Flor de Mayo’, tres con testa de color negro y uno nativo, bajo un diseño de bloques completos al azar con tres repeticiones en R y tres en S, en el ciclo verano-otoño 2014. Se utilizó la dosis de fertilización 80-40-00. La S disminuyó el rendimiento de semilla (30%), la biomasa acumulada a inicio de floración (BMIF) (22%), biomasa acumulada en antesis (BMA) (19%) y la biomasa acumulada en madurez fisiológica (BMMF) (19%) y el índice de cosecha (14%) con respecto a R. La S también redujo los días y grados día a inicio de floración, antesis y madurez fisiológica. Hubo variabilidad dentro del grupo de variedades de frijol evaluadas, resaltando FM 2000 por presentar alto rendimiento de semilla, en promedio de R y S, y en cada condición de humedad (R y S). Mientras que FM RMC sobresalió por exhibir mayor BMIF, BMA y BMMF, tanto en R como en S.
Tiene el amaranto el potencial agronómico para ser un fenómeno mundial como la quinua
Authors: Espitia Rangel Eduardo , Hernández Luisa Fernanda Sesma , Ramos Miriam Gabriela Valverde , Molina Lucila González , López Diana Escobedo , Aguilar Delgado Miriam Jazmín
Published: December 2021

El Amaranto y la quinua pertenecen a la familia Amaranthaceae caracterizada por tener especies que crecen en condiciones adversas, además de presentar altos contenidos de proteínas, ácidos grasos insaturados y vitaminas, además propiedades funcionales, que podrían ser una excelente opción para hacerle frente a los grandes problemas que aquejan al mundo. Debido a estas características la quinua se ha convertido en un fenómeno a nivel mundial y ya se cultiva en más de 100 países. La investigación fue planteada con el fin de determinar si el amaranto tiene el potencial agronómico para incrementar la superficie cultivada como sucedió con la quinua. Se estableció un experimento con tres variedades de quinua y tres variedades de amaranto en tres ambientes de los Valles Altos de México, bajo un diseño de bloques completos al azar con arreglo de tratamientos en parcelas divididas. Se evaluaron variables agronómicas, así como el rendimiento. Los resultados encontrados mostraron que el amaranto superó a la quinua en longitud de inflorescencia, ancho de inflorescencia, diámetro de tallo, peso hectolítrico y rendimiento, mientras que la quinua presentó valores más altos para diámetro de semilla y peso de mil semillas. Los genotipos Tlahuicole y L-145 de amaranto fueron los que observaron mejor comportamiento, seguidos por la variedad Suyana de quinua. El amaranto presenta características para ser un fenómeno a nivel mundial, tal como ha sucedido con la quinua.
La biofortificación con selenio mejora los compuestos bioactivos y la actividad antioxidante en chile jalapeño
Authors: Gaucin-Delgado Jazmín Monserrat , Preciado-Rangel Pablo , González-Salas Uriel , Sifuentes-Ibarra Ernesto , Núñez-Ramírez Fidel , Orozco Vidal Jorge Arnaldo
Published: December 2021

El selenio (Se) es un oligoelemento esencial para la salud humana y en las plantas es considerado un elemento benéfico, al ser un promotor del crecimiento y un detonador de la respuesta antioxidante en las plantas. La biofortificación con Se, tiene como objetivo obtener alimentos ricos en este oligoelemento, de alta calidad nutricional que ayuden a combatir los problemas de desnutrición en la población. El presente trabajo tiene como objetivo evaluar la capacidad del selenato (Na2SeO4) sobre el rendimiento, biosíntesis de compuestos bioactivos y su acumulación en frutos de chile. Para ello cinco tratamientos fueron aplicados vía solución nutritiva: 0, 1.5, 3, 4.5 y 6 mg L-1. En la cosecha, se cuantificó la calidad nutracéutica, la acumulación de Se en frutos, así como el rendimiento del cultivo. La biofortificación con Se modificó positivamente la biosíntesis de compuestos bioactivos y su concentración en fruto, sin disminución en el rendimiento. La incorporación de Se en la solución nutritiva es una opción para obtener alimentos funcionales con una calidad nutracéutica y con la posibilidad de mejorar la salud pública tras su consumo.
Morphogenesis Analysis for Digital Image Production with L-System
Authors: Vatresia Arie , Utama Ferzha Putra
Published: December 2021

The process of forming an image requires a correct color composition, location and distance between the lines to produce a good image. Human abilities in both creativity and high imagination are very limited, especially in forming new images by utilizing existing image patterns or images that resemble old images. Here we showed the implementation of L-System to generate new image generations with additional flame as a fire effect/glow on images for image transformation. This research used the L-System algorithm, Iterated Function System, and Voronoi Diagram to improve the result of image transformation. The results of this study indicated that mathematical calculations can be applied in the formation of images and the resulting images can be abstract and symmetrical. The next generation of images produced in this research can be in unlimited numbers as the generation of morphogenesis processes. The process of generating images is carried out randomly by merging the two existing images with morphogenesis analogy. The resulting images can be exported into jpg, png, and svg formats. Furthermore, this research showed that the implementation of the calculation for the variation reach the value of 99.48% while the image variation composition has a value of 99.29%.
Ethnosciences Based Augmented Reality on Botanical Garden
Authors: Setiyaningsih Yunita , Dijaya Rohman , Suprianto Suprianto
Published: December 2021

Ethnosciences in natural knowledge needs to be developed as a learning material and insight. In the field of education, ethnoscience is not optimal if it is applied in theory or books. Along with the times, the theory of ethnoscience will be displaced by modern technology, therefore the means of knowledge need to be upgraded to more advanced media to gain new experiences, especially for future generations. Researchers are looking for an ethnoscience approach in the field of technology by taking samples of observations of plant species in the Botanical Gardens. The technology used to develop this media is Markerless Augmented Reality based on Android applications. Researchers use 3D plant model objects from plant species in functions for the environment, including: Waste particle absorbing plants; CO2-absorbing and O2-producing plants; Odor-absorbing/removing plants; Plants to deal with flooding; Absorbent/odor depressant plants; Plants to overcome inundation, Groundwater conservation plants; Beach safety and abrasion plants. The results of the implementation and testing of the application are built and run with the android.apk device. This application is called EARBot (Ethnoscience Based Augmented Reality on Botanical Garden) which is an educational application of knowledge about ethnoscience that uses Markerless Augmented Reality technology.
Corn Disease Classification Using Transfer Learning and Convolutional Neural Network
Authors: Adhinata Faisal Dharma , Fitriana Gita Fadila , Wijayanto Aditya , Putra Muhammad Pajar Kharisma
Published: December 2021

Indonesia is an agricultural country with abundant agricultural products. One of the crops used as a staple food for Indonesians is corn. This corn plant must be protected from diseases so that the quality of corn harvest can be optimal. Early detection of disease in corn plants is needed so that farmers can provide treatment quickly and precisely. Previous research used machine learning techniques to solve this problem. The results of the previous research were not optimal because the amount of data used was slightly and less varied. Therefore, we propose a technique that can process lots and varied data, hoping that the resulting system is more accurate than the previous research. This research uses transfer learning techniques as feature extraction combined with Convolutional Neural Network as a classification. We analysed the combination of DenseNet201 with a Flatten or Global Average Pooling layer. The experimental results show that the accuracy produced by the combination of DenseNet201 with the Global Average Pooling layer is better than DenseNet201 with Flatten layer. The accuracy obtained is 93% which proves the proposed system is more accurate than previous studies.
Performance Evaluation of Contract Employees Using the Best-Worst and Simple Additive Weighting Methods
Authors: Gustriansyah Rendra , Alie Juhaini , Suhandi Nazori
Published: December 2021

All companies need qualified employees to ensure the continuity and progress of the company. Therefore, some companies are very selective in evaluating employee performance based on the criteria set by the company. However, because of the many criteria used in the assessment, a large number of contract employees to be evaluated, and the evaluation that must be proportional, the Human Resources department has difficulty evaluating the performance of contract employees. Therefore, this study aimed to develop a system for evaluating the performance of contract employees by integrating the Best-Worst (BW) and Simple Additive Weight (SAW) methods. The BW method is used to determine the weight of each criterion related to the performance appraisal of contract employees, and the SAW method is used to evaluate the performance of contract employees. The results showed that the system developed can provide a more proportional evaluation. So, this study contributes as a recommendation system for HR managers in determining eligible contract employees to have their work contracts extended based on criteria determined by the company.
Real-time Vehicle Surveillance System Based on Image Processing and Short Message Service
Authors: Wibowo Agustinus Deddy Arief , Heriansyah Rudi
Published: December 2021

This paper proposes a real-time vehicle surveillance system based on image processing approach tailored with short message service. A background subtraction, color balancing, chain code based shape detection, and blob filtering are used to detect suspicious moving human around the parked vehicle. Once detected, the developed system will generate a warning notification to the owner by sending a short message to his mobile phone. The current frame of video image will also be stored and be sent to the owner e-mail for further checking and investigation. Last stored image will be displayed in a centralized monitoring website, where the status of the vehicle also can be monitored at the same time. When necessary, the stored images can be used during investigation process to assist the authority to take further legal actions.
Fungsi Implikatur Percakapan pada Tuturan Para Pelaku Talk Show Hotman Paris Show Unggahan Youtube 2020
Authors: Suroso Eko , Fathonah Siti
Published: December 2021

Ketika peneliti melihat acara talk show Hotman Paris Show di youtube Januari 2020, peneliti menemukan tuturan Kamu diundang ke sini sebatas entertaiment kalau saya terima kado dari kamu, nanti saya seolah saya menghianati klien saya. Jadi kita hanya diskusi sebatas dunia akting tidak membahas kasus makanya pertama suara kamu kok bikin jangkrik bangun. Pada tuturan itu tampak adanya implikatur percakapan dengan fungsi menyatakan. Fungsi implikatur percakapan yang lain juga peneliti temukan pada beberapa percakapan yang berbeda. Permasalahan yang kemudian muncul adalah Fungsi Implikatur apa sajakah yang terdapat pada Para Pelaku Talk Show Hotman Paris Show Unggahan Youtube 2020? Impilikatur adalah penggunaan makna dibalik makna yang harfiah (makna non natural). Fungsi tuturan adalah Tuturan yang disampaikan penutur dengan maksud tersirat kepada mitra tutur. Fungsi tuturan itu ada tiga yaitu menyatatakan, menanyakan, dan menyuruh. Penelitian ini dilaksanakan dengan pendekatan deskriptif kualitatif. Data penelitian ini adalah tuturan Para Pelaku Talk Show Hotman Paris Show.  Teknik pengambilan data dilakukan dengan teknik simak bebas libat cakap. Analisis  data dilakukan  dengan teknik padan pragmatik. Hasil penelitian menunjukkan bahwa tuturan para pelaku pada Talk Show Hotman Paris Show memiliki tiga fungsi implikatur percakapan yaitu fungsi menyatakan (Terbanyak), menanyakan (Cukup banyak), dan memerintah (sedikit).
Teks Anekdot dalam Web Guru Pendidikan (Pola, Struktur, Pesan Moral, dan Relevansinya bagi Pembelajaran Bahasa Indonesia SMA Kelas X)
Authors: Fitria Mutiara Indah , Kuntoro Kuntoro
Published: December 2021

Penelitian ini bertujuan mendeskripsikan pola, struktur, pesan moral, dan relevansi penelitian dengan pembelajaran bahasa Indonesia SMA Kelas X. Jenis penelitian ini adalah deskriptif kualitatif. Pendekatan yang digunakan adalah pendekatan pragmatik. Data pada penelitian ini adalah teks yang mengandung unsur Pola, Struktur, Pesan Moral di dalam teks anekdot Web Guru Pendidikan. Sumber data pada penelitian ini adalah teks anekdot Web Guru Pendidikan. Teknik pengumpulan data penelitian ini menggunakan teknik baca dan teknik catat. Teknik analisis datanya meliputi reduksi data, menyajikan data, dan kesimpulan. Validitas data menggunakan triangulasi teori. Hasil penelitian ini yaitu (1) 31 data dari teks anekdot menggunakan pola narasi, (2) 37 data teks anekdot menggunakan pola dialog, (3) 1 data menggunakan pola anekdot dan pola narasi. Struktur teks anekdot (1) 1 data terdapat struktur abstrak, orientasi, krisis, reaksi, dan koda, (2) 55 data terdapat struktur abstrak, orientasi, krisis, dan reaksi, (3) 1 data terdapat struktur abstrak, orientasi, krisis, dan koda, (4) 4 data merupakan struktur yang terdiri dari abstrak, krisis, reaksi, dan (5) 8 data terdapat struktur abstrak, orientasi, dan krisis. Menemukan 9 pesan moral (1) menghargai orang lain, (2) disiplin, (3) jujur, (4) kerja keras, (5) adil, (6) bertanggung jawab, (7) religius, (8) demokratis, (9) toleransi. Berdasarkan relevansi penelitian terhadap pembelajaran, penelitian ini dapat digunakan sebagai bahan ajar siswa dan sebagai media pendidikan karakter.
Pengaruh Operating Capacity, Sales Growth, Arus Kas dan Leverage Terhadap Financial Distress
Authors: Khasanah Siti Noviati Uswatun , Sukesti Fatmasari , Nurcahyono Nurcahyono
Published: December 2021

This research was conducted the empirically prove the factors that influence Financial Distress by using the variables operating capacity, sales growth, cash flow, and leverage in transportation companies listed on the Indonesia Stock Exchange in 2015–2020. This type of research is quantitative research with sampling technique using purposive sampling method, namely the selection of samples with criteria determined by the researcher. The method used in this study uses multiple linear regression with the help of the SPSS version 25 program. The results in this study indicate that operating capacity has a positive effect on financial distress, which means that a low operating capacity value will cause financial distress. Sales growth and cash flow do not effect financial distress, which means the size of the value of sales growth and cash flow does not affect the occurrence of financial distress. Leverage has a positive effect on financial distress, which means that the high value of debt will cause financial distress.
ALLOZA APARICIO, Ángel, FERNÁNDEZ IZQUIERDO, Francisco y GARCÍA GUERRA, Elena (eds.), A la sombra de la fiscalidad. Estudios sobre apropiación y gestión de rentas y patrimonios en Castilla. Siglos XV-XVII. Madrid, Sílex, 2019
Authors: Jiménez Estrella Antonio
Published: December 2021

En los últimos años venimos asistiendo a una abundante producción de estudios sobre la fiscalidad regia en la Monarquía de los Habsburgo que ha arrojado nuevas luces sobre la organización y gestión de la tupida y compleja red de rentas reales castellanas en dicho período, el funcionamiento y evolución de los órganos administrativos de los que dependían, los mecanismos de control y fiscalización contable, la vinculación de su cobro y administración con importantes redes de financieros y agentes de crédito por la vía de los arrendamientos o el papel de las oligarquías ciudadanas en los encabezamientos, entre otros muchos temas que afectaban al funcionamiento la hacienda regia…
NEW ISOTOPE-GEOCHEMICAL DATA ON THERMAL WATERS OF THE TALSKOE DEPOSIT (MAGADAN OBLAST)
Authors:   Far East Geological Institute, Far East Branch, Academy of Sciences, Bragin I.V. , Chelnokov G.A. ,   Far East Geological Institute, Far East Branch, Academy of Sciences, Kharitonova N.A. ,   Far East Geological Institute, Far East Branch, Academy of Sciences
Published: December 2021

In this paper, we summarize new data on the chemical and isotopic composition of thermal wa-ters of the Talskoye deposit in the Magadan Oblast. We were the first to obtain the data on the content of stable oxygen (δ18O) and hydrogen (δD) isotopes in thermal and background waters, as well as oxygen (δ18O) and carbon in bicarbonate ion (δ13C), even though this is the largest ex-ploited deposit of low-mineralized alkaline nitric thermal waters in the region. The thermal water is fresh (M = 980 mg/l), alkaline (pH = 8.9), hydrocarbonate-chloride-sulphate sodium with a high content of fluorine (up to 17 mg/l) and silicic acid (up to 152 mg/l). The deposit is fed by atmospheric precipitation; we did not find traces of melting underground ice supply. A sequential scheme for calculating the temperature of a deep reservoir was applied, which allowed the temperature of water formation to be constrained at 108 °C suggesting an input of fluids rich in potassium and sulfate ion.
NEW DATA ON THE AGE AND LITHOLOGICAL COMPOSITION OF THE LIMAN FORMATION OF SAKHALIN ISLAND
Authors:   LLC RN-Shelf-Arctic, Kovtunovich P.Yu. , Safronova L.S. ,   LLC RN-Shelf-Arctic, Oreshkina T.V. ,   Geological Institute of the Russian Academy of Sciences, Tsoy I.B. ,   V.I. Il’ichev Pacific Oceanological Institute, Far Eastern Branch, Russian Academy of Sciences, Dmitrieva T.V. ,   Stock Company "All-Russian Petroleum Research Geological Prospecting Institute"
Published: December 2021

For the first time, from the lower part of the stratotype of the Liman Formation (district of the Mount Liman) data on diatoms and silicoflagellates were obtained, which allowed us to assign this part of the Liman Formation to the end of the Middle – beginning of the Late Miocene (Denticulopsis praedimorpha Zone, 12.9–11.5 Ma and Thalassiosira yabei Zone, 11.5–10.0 Ma by diatoms) and to establish the marine genesis of the host deposits. The upper part of the Liman Formation (district of the Peata cape) containing continental deposits, probably refers to the Late Miocene (?) – Calabrian Stage (Eopleistocene).
Active search about latex in injectable drugs for patient’s safety in medical therapy
Authors: PEIXE Roberta G. , SODRÉ Maria C. , OLIVEIRA Beatriz B. , GONÇALVES Luana P. , HALM Ian G. , CRUZ José C. , ANTUNES Ana P. , AMANCIO Rodrigo T.
Published: December 2021

Objectives: To classify injectable drugs used in a general hospital inventory according to latex presence or absence in vials with rubber stoppers, antibiotics, and electrolytes bags. Methods: The information about latex content has been collected from medicine industries, after identification of authorized manufacturers in Brazil, through the National Health Surveillance Agency (ANVISA) medicine search database. Medicines have been grouped per pharmaceutical manufacturers, and data were collected through telephone or e-mail. Only written information from pharmaceutical companies were considered. Results: Among 161 medicines used in the hospital packaged in vials with rubber stoppers, antibiotics, and electrolytes bags, 123 (76.4%) medicine-related responses were received, covering 540 (82.2%) different presentations. For this, from 87 contacts, 70 (80.5%) companies responded and 65 (74.7%) provided information related to the presence or absence of the allergen. Among the medicine list, 8 (6.5%) were identified as containing latex (in 12 different presentations – 2.2%) and 101 medications (82.1%) in 507 presentations (93.9%) do not contain latex. The manufacturers responded that the medicine was latex-free, but could not confirm for raw materials (6 medicines – 4.9% - in 6 different presentations – 1.1%) and that they were unable to ensure there was no contact with latex during manipulation (4 medicines – 3.3% - in 8 different presentations – 1.5%). For 4 medicines (3.3%) in 7 different presentations (1.3%), the companies were inconclusive, as they could not confirm whether they were latex-free or not. Conclusion: Although latex is a known allergen, information about the presence of latex components in pharmaceutical packaging and package inserts needs improvement, since the active search identified 161 medicines packaged in vials with rubber stoppers, antibiotics, and electrolytes bags that failed to depict this information. The results of this survey endorse the Importance of displaying this information on medicines label or packaging in order to ensure healthcare professionals easy access and prompt consultation.
Features of CD-­­phenotype of peripheral blood lymphocytes in adult patients with atopic dermatitis during the exacerbation
Authors: Aleksandruk O.D.
Published: December 2021

Objective — to study the dynamics of peripheral blood lymphocytic populations in adult patients with atopic dermatitis (AD) with the onset of the disease in childhood, depending on the level of IgE secretion and the method of treatment.

Materials and methods. We examined 67 adult patients with AD, which were divided into 4 groups depending on the level of total serum IgE and the basic treatment or treatment in combination with Glycine and Ketotifen. The severity of AD was determined by the SCORAD index. The content of peripheral blood lymphocytes according to the phenotype CD3+, CD4+, CD8+, CD19+, CD65+, HLADR+ and CD95+ was assessed during hospitalization of patients, at the end of the inpatient stage of treatment and after 1 month of outpatient follow-up. The obtained data were compared with the indices of the control group and between the groups of examined patients with AD in the dynamics of their treatment and observation. The results were processed statistically using the methods of parametric and nonparametric statistics.

Results and discussion. The indices of the number of cells of peripheral lymphocytic populations of different CD pheno­type in the groups in the dynamics of observation were determined, their relationship with the severity of the course of AD was established, and differences were found depending on the pathogenetic variant of AD. Against the background of an exacerbation of AD, a significant increase in the number of cells in most of the defined populations was revealed, with its gradual decrease as the clinical manifestations of AD subsided. It was established that 1 month after achievement of clinical/subclinical remission, a part of the peripheral blood lymphocytic populations was characterized by higher values compared to the norm. In patients with an IgE-dependent AD variant, aggravation is accompanied by high levels of peripheral lymphocytes with CD3+, CD4+, CD8+, CD19+ and HLA-DR phenotypes, which more often than in the case of an IgE-independent variant of AD, remain above the norm after 1 month of outpatient monitoring. Introduction of glycine and ketotifen to the treatment complex for patients with AD is accompanied by a faster return of peripheral lymphocyte cells to normal values, which is more evident in patients with an IgE-dependent variant of AD.

Conclusions. In adult AD patients, the dynamics of the number of peripheral lymphocyte population cells depends on the severity of the disease, its pathogenetic variant and the treatment received by the patient. Against the background of the use of glycine and ketotifen, the normalization of indicators of peripheral lymphocytic populations occurs significantly faster than with only standard basic therapy.
Safety and clinical efficacy of bilastine in reduction of pruritus in patients with chronic spontaneous urticaria
Authors: Bogomolov A.Ye.
Published: December 2021

Objective — to evaluate the efficacy/safety of bilastine in relieving pruritus in patients with chronic spontaneous urticaria.

Materials and methods. This prospective randomized study included 50 adult patients aged 18 to 59 years with chronic spontaneous urticaria and pruritus with an intensity of more than 4 points by the visual analog scale of pruritus assessment in the last 3 days and more than 16 points by the Urticaria activity score 7 (UAS7) which assessed chronic urticaria intensity for the last week.Patients received bilastine orally at a dose of 20 mg once a day for 8 weeks. Patients who did not respond to therapy within the first 2 weeks subsequently received bilastine at a dose of 40 mg per day (two 20 mg tablets) till the end of the study (for 6 weeks).

Results and discussion. The mean age of patients was 39.61 years with standard deviation (SD) of 12.33 years. In the group of patients who responded positively to the initial therapy, within 8 weeks, the pruritus intensity scoring level decreased significantly to 0.46 (95 % CI: 0.14—0.78) points (p < 0.05). The patients who received a double dose of bilastine also revealed a decrease in the intensity of pruritus and on average on the 8th week of treatment had 0.48 (95 % CI: 0.26—0.70) points (p < 0.05).The study reported 14 adverse events (AE) that occurred during bilastine treatment in 10 (23.8 %) patients. All of them were classified as mild and the most common was headache, registered in 12 (85.7 %) cases. No moderate or severe AEs were reported during the study.

Conclusions. 8 week treatment with bilastine has demonstrated proven clinical efficacy both in reducing the urticaria activity index according to UAS7 and in reducing the intensity of pruritus in the absence of moderate and severe AEs. Patients who did not respond to starting therapy after doubling the bilastine dose also significantly decreased the urticaria activity index according to UAS7 and reduced the intensity of pruritus. At the same time, increasing the dose of the drug did not lead to an increase in the frequency of AEs.
Awareness and knowledge of sexually transmitted diseases among population in Georgia (epidemiological survey)
Authors: Shvelidze M. , Durglishvili N. , Kvirkvelia V. , Gagua G. , Kolyadenko К.
Published: December 2021

Sexually transmitted infections (STIs), often known as sexually transmitteddiseases, are still a major public health concern across the world. According to WHO estimates, sexually transmitted diseases (STIs) have an annual incidence of 357 million cases among which chlamydia (131 million), gonorrhoea (78 million), syphilis (5.6 million) and trichomoniasis (143 million), half of those among young people aged 15—24. Every day, almost one million people worldwide develop an STI, and the majority of them are ignorant of their infection status, making them a source of infection for others. The frequency and consequences of this on the health and socioeconomic condition of whole nations, particularly African countries, have long been regarded as a serious emergency. The epidemiology of STIs, the history and physical findings, screening standards, and the overall approach to combat STIs are all covered in this article. Infections covered in terms of causation, epidemiology, and risk factors include gonorrhea, Chlamydia trachomatis, Trichomonas vaginalis, syphilis and trichomoniasis. For a variety of reasons, the worldwide illness burden represented by STI remains unclear. First, many STIs are asymptomatic; second, diagnostic procedures are unavailable in some of the most affected nations; and finally, surveillance systems are non-existent or very poor in many parts of the world. According to the World Health Organization, there were 340 million new cases of syphilis, gonorrhoea, chlamydia infection, and trichomoniasis in 1999. In the European Union, there has been an increase in the incidence of gonorrhoea and syphilis in recent years. The survey instrument was an online self-administered anonymous questionnaire conducted in Georgia using Google survey software, which automatically populates and saves digital responses to a secure database protecting participant confidentiality throughout the surveying process. The survey was conducted in 2019. The opportunity to participate in the questionnaire was one-time. The question naire for this study was developed based on a review of literature.Health education, early diagnosis and treatment, screening for asymptomatic infections, contact inquiry, and immunization for illnesses for which a vaccine is available should all be used in STI prevention and control. In general, the studies reported low levels of knowledge and awareness of sexually transmitted diseases. Although, as shown by some of the findings on condom use, knowledge does not always translate into behavior change, adolescents’ sex education is important for STD prevention, and the school setting plays an important role.
Peran pendidikan karakter dalam penggunaan media sosial bagi remaja
Authors: Safitri Aizun Riski , Anggraini Dian Mego , Mujahida St. Helmia , Muhyatun Muhyatun
Published: December 2021

Pengguna media sosial saat ini didominasi oleh remaja yang kemudian mengalami perubahan kearah perilaku negatif dan yang tidak sesuai dengan nilai-nilai luhur bangsa. Remaja saat ini sangat mudah untuk mengakses informasi dengan internet secara bebas dan tidak ada batasan, termasuk dengan berbagi konten-konten yang bersifat amoral. Bahkan demi viral di media sosial remaja rela melakukan apapun termasuk dengan membuat konten negative dan berbau asusial. Hal ini merupakan efek dari penggunaan media sosial yang berlebihan dan tanpa kontrol baik dari pemerintah dan orang tua serta peran serta masyarakat. untuk iu pendidikan karakter di sekolah bisa menjadi usaha prefentif perubahan perilaku remaja dalam penggunaan media sosial, karena pendidikan karakter berperan penting dalam mengontrol dan meningkatkan kesadaran remaja dalam menggunakan media sosial.
Pengaruh komunitas di MTs Mambaul Ulum Bata-Bata Kelas VIII terhadap kepribadian santri
Authors: Nafila Nafila , Budianto Ahmad Andry , Rahmawati Roro Kurnia Nofita
Published: December 2021

Penelitian ini dailaksanakan umtuk mengetahui pengaruh komunitas terhadap kepribadian santri. Metode penelitian yang digunakan dalam penelitian ini ada kuantitatif dengan menggunakan regresi linier, adapaun hasil analisis yakni diperoleh nilai regresi sebesar 32,589 lebih yang besar dari pada r tabel sebesar 0,266 pada taraf signifikasi 0,05 dengan demikian maka dapat di interpretasikan jika “Terdapat pengaruh yang signifikan antara Komunitas (Variabel X) terhadap kepribadian santri   (Variabel Y)”. kesimpulan dari hasil penelitian ini Angka konstan dari unstandardized coefficients dalam penelitian ini nilainya sebesar 32,589. Angka ini merupakan angka konstan dengan mempunyai arti jika tidak ada nilai komunitas (X) maka kepribadian (Y) adalah 32,589. Angka koefisien regresi nilainya sebesar -140. Angka ini mengandung arti bahwa setiap penambahan 1% komunitas (X) maka kepribadian (Y) akan berkurang sebesar -140, Ada pengaruh negatif (-) antara variabel X dan variabel Y, Berdasarkan hasil analisis tersebut dapat di interpretasikan jika terdapat pengaruh adanya komunitas terhadap kepribadian santri.
Profil minat belajar siswa dalam pembelajaran daring
Authors: Sodik Indah Rosyidah , Rufaidah Anna , Susiati Susiati
Published: December 2021

The aimed of this study was to determine the profile of students' interest in learning in online learning during the pandemic and its implications for guidance and counseling services at SMA Islam As-Syafi'iyah 01. The approach used in this study was a descriptive quantitative approach. The research sample used the purposive sampling technique, which was 105 students of class XI SMA Islam As-Syafi'iyah. This research was conducted by distributing an instrument in the form of a learning interest questionnaire in online learning. Analysis of research data using descriptive statistics. The results of the study regarding the profile of learning interest indicate that interest in learning in online learning at SMA Islam As-Syafi'iyah is in the Medium category, which is 84%
Assessment of neurofunctional activity in patients with vibration disease caused by combined effects of local and general vibration
Authors: Shevchenko Oksana I. , Rusanova Dina V. , Lakhman Oleg L.
Published: December 2021

Introduction. The authors note insufficient knowledge of pathophysiological mechanisms, the cumulative role of cerebral functioning disorders in the formation of sensorineural deficit in vibration disease (VD). The study aims to identify changes in indicators characterizing neurofunctional activity in patients with VD due to the combined effects of local and general vibration. Materials and methods. The study involved 42 patients with VD (group I), 35 healthy men (comparison group). Researchers used methods of electroneuromyography, neuroenergic mapping, and neuropsychological testing. Results. In group I, when compared with the comparison group, we have detected an increase in latency N9, N10, N11, N13, N25, N30, the duration of the peak interval N10-N13 (p=0,002; 0,0001; 0,0002; 0,0001; 0,0023; 0,005; 0,01 respectively); an increase in local levels of constant potential (LCP) in the frontal, central, right parietal, occipital, right temporal parts of the brain (p=0.037; 0.0007; 0,0005; 0,01; 0,0004; 0,014; 0,029; 0,028; 0,001 respectively). Cognitive impairments in patients with VD correspond to an easily expressed disorder of analytical-synthetic and conceptual thinking, short-term (auditory-speech), visual imagery, long-term memory, dynamic praxis, joint coordination, impressive and expressive speech. The revealed conjugacy of the indicators of the LCP of the frontal left abduction, and the latency of the peak N30, duration N13-N20, and the hand of analytical and synthetic thinking (r=0.51, p=0.004; r=0.50, p=0.005, respectively) indicates the pathogenetic significance in the violation of neurofunctional activity of a decrease in cortical activation as a result of the arrival of a sensory message from the brain stem to the cortex, increased energy exchange in the frontal part of the left hemisphere. Conclusions. A sign of impaired neurofunctional activity in VB from the combined effects of local and general vibration is a decrease in the postsynaptic action of neurons, the time of signal passage through afferent pathways at the level of the cervical spinal cord, dynamic praxis, short-term (auditory-speech) memory, increased energy metabolism in the temporal right and left frontal brain.