bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of the processing conditions on the production of expanded or plasticized wood plastic composite with cashew nutshell powder
Authors: Silva William C. L. , Almeida Júlia N. S. , Silva Natália F. I. , Pereira Isabela C. B. , Sousa Ítalo R. B. A. , Santos Jakeline R. D. , Ueki Marcelo M. , Pisanu Luciano , Santos Luís H. S. , Medeiros Eliton S. , Wellen Renate M. R. , Barbosa Josiane D. V. , Santos Amelia S. F.
Published: June 2024

In this work we investigate the influence of closed (“C”) or open (“O”) extrusion degassing, and low (5 MPa – “L”) or high (90 MPa – “H”) holding pressure during injection molding on the properties of wood-plastic composite (WPC) based on high-density polyethylene (HDPE) flakes compatibilized with 5 wt% maleic anhydride-modified polyethylene (MAPE), 5 wt% lubricant (Struktol® TPW 113), and 40 wt% cashew nutshell powder (CNSP). Two reference compounds were extruded with closed degassing and injected at 90 MPa of holding pressure: (1) HDPE flakes extruded with 5 wt% MAPE and 5 wt% Struktol® TPW 113 (HDPEad_C-H) and (2) HDPE flakes previously melt mixed in an internal mixer with 5 wt% CNSL (HDPEr/5CNSL) and then extruded with the same additive content (HDPEad/5CNSL_C-H). At 90 MPa holding pressure, the extract content of WPC slightly increased and CNSL acted as a lubricant and poor plasticizing agent, reducing the crystallinity and density of the additivated matrix (HDPEad_C-H), increasing the flow rate without significantly changing the tensile strength. On the other hand, low holding pressure (5 MPa) favored the volatilization and expansion of the residual CNSL in the WPC, which acted as a blowing agent improving filling of the mold cavity and avoiding sink marks. Sample extruded with open degassing (atmospheric pressure) did not significantly change the extract content, but favored CNSL diffusion from particles to matrix, which subsequently during injection molding led to its entrapment at the interface, resulting in low adhesion, especially at high holding pressure that hinders CNSL expansion and vaporization. These findings contribute to understand the role of residual CNSL of CNSP in WPC properties and thus, to strengthen the plastics recycling chain and reduce carbon footprint.
Depth of intact vascular plexus – visualized with optical coherence tomography – correlates to burn depth in thoracic thermic injuries in children
Authors: Dalicho Valerie , Straube Tina , Kelly Kathrin , Larsen Beke , Wünsch Lutz , Lindert Judith
Published: June 2024

Objectives

Deep thermal injuries are among the most serious injuries in childhood, often resulting in scarring and functional impairment. However, accurate assessment of burn depth by clinical judgment is challenging. Optical coherence tomography (OCT) provides structural images of the skin and can detect blood flow within the papillary plexus. In this study, we determined the depth of the capillary network in healthy and thermally injured skin and compared it with clinical assessment.

Methods

In 25 children between 7 months and 15 years of age (mean age 3.5 years (SD±4.14)) with thermal injuries of the ventral thoracic wall, we determined the depth of the capillary network using OCT. Measurements were performed on healthy skin and at the center of the thermal injury (16 grade IIa, 9 grade IIb). Comparisons were made between healthy skin and thermal injury.

Results

The capillary network of the papillary plexus in healthy skin was detected at 0.33 mm (SD±0.06) from the surface. In grade IIb injuries, the depth of the capillary network was 0.36 mm (SD±0.06) and in grade IIa injuries 0.23 mm (SD±0.04) (Mann–Whitney U test: p<0.001). The overall prediction accuracy is 84 %.

Conclusions

OCT can reliably detect and differentiate the depth of the capillary network in both healthy and burned skin. In clinical IIa wounds, the capillary network appears more superficial due to the loss of the epidermis, but it is still present in the upper layer, indicating a good prognosis for spontaneous healing. In clinical grade IIb wounds, the papillary plexus was visualized deeper, which is a sign of impaired blood flow.
Biased interrogatives in Camuno
Authors: Fiorini Matteo
Published: June 2024

This article discusses the properties of interrogative structures biased in the set of their possible answers by the particle po in Camuno. In declarative structures, po signals that according to the speaker, a proposition p is surprisingly controversial in the utterance world w. In interrogative structures, the same particle identifies the only subset of

〚

p
〛

f

[\kern-2pt[ {p]\kern-2pt] }^{f}

, the set of focus alternatives to p, that can satisfy the existential presupposition introduced by the question. However, po additionally signals that such a subset is non-factual, i.e., controversial, in w. A characterization of po as an element operating on sets of alternatives offers an important tool to investigate the numerous pragmatic readings conveyed by po and account for the restrictions in its distribution. The semantic properties of the po-interrogatives can, in fact, capture the mirative and counterfactual readings also attested in cognate forms in neighboring varieties. Thus, this analysis represents an important step in exploring a possible unified account.
Come lavorava Lucano? Su possibili varianti d’autore nel Bellum civile
Authors: Russotti Ambra
Published: June 2024

That authorial variants survive in the transmission of the works of Lucan is a hypothesis legitimated by some objective data, yet the problem has been given very little attention in research since the important discussion by Fraenkel (1926). The present paper offers an analysis of the question that starts from the cases already identified and discussed by Fraenkel, adding some examples newly identified here. In particular, the goal is not to discuss single cases evaluated separately, but rather to examine the distribution of suspected variants in coherent macro-systems, the shared ratio of which could offer a plausible way of establishing an authorial intervention. In their turn, the systems of variants proposed and discussed here allow us to advance hypotheses about Lucan’s compositional method.
Conflicting modalities in feature film: from contrapuntal editing to internal diegetic sound
Authors: Oja Martin
Published: June 2024

This article approaches sensory modalities as semiotically active factors and organizing principles in meaning-making. The focus will be on the special case where modalities mismatch in film – i.e., the soundtrack and visuals present contradictory meanings. The conflict can be characterized by the concept of synthesis that emerges in theories of Eisenstein, Barthes, Jakobson, Lotman, and cognitivists. The artistic functions of such synthesis will be discussed with the help of examples from selected feature films. In the first place, conflicting modalities are inspected in the light of Juri Lotmanʼs theory of two incompatible, but still complementary languages that make up a mechanism for generating new information. In addition, the prospects of evaluating modality conflicts will be touched upon, dismissing synchrony and redundancy as the scale parameters, but acknowledging Lotmanʼs model of space as a primary modeling system that is capable of representing semantic conflicts.
Combining formal and functional approaches to variation in (morpho)syntax: Introduction to the special issue
Authors: Strobel Thomas
Published: June 2024

This special issue examines the question of how both formal(ist) and functional(ist) accounts or elements of theorizing can contribute to the explanation of (morpho)syntactic variation. Are formal and functional approaches really irreconcilable with each other, as often seems to be taken for granted by their respective advocates? It will be argued instead that they are rather complementary and that both can make a valuable contribution to explaining linguistic variation, in synchronic as well as diachronic respects. The integration of ways of looking at a certain phenomenon or problem from the respective other camp is proven to provide a significant added value and should not be excluded. The volume focuses on several Germanic languages and dialects, more specifically on German, Dutch, and Swedish varieties. It unites different formal and functional perspectives and, not least, it considers also semantic and phonological factors. The models covered include different versions of generative grammar, information-based morphology, construction grammar/construction morphology, natural morphology, and sociolinguistics.
On the asymmetry of wh-doubling in varieties of German and Dutch
Authors: Fanselow Gisbert , Barbiers Sjef , Brown Jessica M. M. , Delbar Natasja , Nauta Sophia , Rothert Johannes
Published: June 2024

This paper combines experimental, theoretical and quantitative approaches to syntactic microvariation. The empirical goal is to clarify the situation with respect to wh-doubling (also: wh-copying) in varieties of German and Dutch. With a large-scale survey in the German and Dutch language areas we sought to establish which speakers allow wh-doubling, which speakers allow right-complexity, i.e., configurations in which the lower copy of the wh-dependency is more complex that the higher one, and which speakers allow left-complexity, i.e., the reverse, with a more complex higher copy. We also wanted to know whether there are associations between these properties, to identify groups of speakers and dialects. We found three types of grammars: (i) a grammar that allows both wh-doubling and right- and left-complexity, (ii) a grammar that allows wh-doubling and has a strong preference for right-complexity over left-complexity, and (iii) a grammar that does not allow any wh-doubling configuration. This shows that there is a clear limit to variation in this domain. Grammars with a preference for left-complexity do not exist. We then point out the consequences of these findings for the copy theory of movement, and for analyses that enrich this theory with the option of partial deletion.
Exploring structural and optical properties of shock wave-loaded polycrystalline picric acid: implications for molecular engineering applications
Authors: Vijayan Muthuvel , Aswathppa Sivakumar , Kumar Raju Suresh , Haribabu Arul , Sathiyadhas Amalapushpam Martin Britto Dhas
Published: June 2024

The shock wave impact on hydrogen-bonded organic materials’ structural properties and their responses with respect to their associated functional properties is one of the most prevalent research topics because of the possible emergence of unusual functional properties. Presently, we intend to examine the structural response of the poly-crystalline picric acid samples under shocked conditions. The crystallographic structural responses and the linear optical properties of the test samples have been examined by powder XRD analysis, ultra-violet diffused reflectance spectroscopy (UV-DRS) and Raman spectroscopy, respectively. Under shocked conditions, a considerable modification in the diffraction peak positions and their intensity changes could be witnessed. Notably, linear optical transmittance profiles show remarkable changes according to the number of applied shock pulses, such that the 150-shocked sample has the highest optical transmittance of 53.9 % at 350 nm, whereas the control sample has an optical transmittance of 6.6 %. The Raman spectrum shows the vibrational groups of material that are stable in shocked conditions with similar intensity changes. Based on the obtained XRD, UV-DRS and Raman results, shock wave-induced picric acid samples have remarkably improved characteristics of optical transmittance, which is highly favorable for non-linear optical applications.
Change management in healthcare – a scoping literature review
Authors:   Jagiellonian University Medical College, Poland, Bąk Danuta , Bąk Sylwia ,   Jagiellonian University, Poland
Published: June 2024

The healthcare sector is constantly changing due to many different factors, both external and internal, such as regulatory, organizational, technological, personnel, financial, and geopolitical change. Change management methods and tools are useful for effectively planning, implementing and monitoring change. The important issue is in which areas and to what extent change management is utilized in healthcare. The aim of this text is therefore to conduct a scoping literature review on change management in healthcare and to develop, based on the results of this research, a theoretical model of determinants and motives for implementing change management in healthcare. A scoping review of the literature was conducted to determine the extent to which change management is applied in healthcare organizations. Texts meeting the inclusion criteria were searched for in four databases: PubMed, Embase, Scopus, and EBSCO. The search was limited to texts published in English. Of the 247 publications screened, 73 met the inclusion criteria. Additionally, 1021 keywords were selected from the screened publications, of which 137 met the inclusion criteria and were approved for the keyword analysis. The keywords formed seven thematic clusters: human, change management, organization and management, leadership, healthcare delivery, hospital management, and productivity. There are a number of motives for using change management in healthcare, and all centre around a few determinants that can be divided into those directly related to the specifics of the healthcare sector and those directly related to management processes. These determinants and motives were included in the theoretical model.
Identification of awareness of the conditions for using cryptocurrencies in Poland
Authors:   University of Warsaw, Poland, Zborowski Marek , Chmielarz Witold ,   University of Warsaw, Poland
Published: June 2024

The primary aim of this article is to identify internet users' knowledge and awareness of cryptocurrencies and the determinants of their use in Poland. The study, which used the CAWI (Computer-Assisted Web Interview) method, was conducted on a group of 400 active Internet users selected through random and purposive sampling. In the survey, which was carried out in April/May 2022 in Poland, respondents were asked to evaluate cryptocurrencies taking into account the following criteria: familiarity with the concept of cryptocurrency, sources of information about the phenomenon, investment preferences, security awareness, and the respondents' knowledge of the advantages and disadvantages of cryptocurrencies. As a continuation of previous research undertaken in this area, the research demonstrated a strong understanding of the respondents concerning the lack of transparency associated with cryptocurrencies and the cryptocurrency market. The main concerns when using cryptocurrencies are: lack of protection against speculators, lack of supervision by a reputable financial institution, and lack of control of the cryptocurrency market by the National Bank of Poland (NBP). The conclusions and recommendations contained in this article may contribute to increasing knowledge and awareness of the phenomenon analysed, and increasing its popularity in society. Additionally, it provides insights for investors regarding the direction of cryptocurrency development.
Online teaching readiness of staff during the COVID-19 pandemic: Ege University sample
Authors:   Ege University, Turkey, Kiliç Murat , Ateç-Çobanoğlu Alev ,   Ege University, Turkey
Published: June 2024

The instant transition to online learning during the pandemic led to some neglections in instructional design and planning, with online teaching readiness seen as a major issue within this context. The authors of this study therefore believe that the readiness of instructors for providing online learning is a critical concern for such a transition and its future implications. In this survey/descriptive study, the authors investigated instructors’ online teaching readiness through an adapted version of Chi’s Online Teaching Readiness Questionnaire, which includes both open-ended and multiple-option questions, with code-theme relationships also presented. The data collection tool was administered to 200 instructors from different faculties working at Ege University, which is a western state university in Turkey. The findings from the questionnaire show that to a large extent, the instructors feel ready for online teaching. The authors share their suggestions on future research and applications in the last section of the paper.
Mesenteric panniculitis on 18F-FDG-PET/CT caused by G-CSF therapy mimicking recurrence of lymphoma
Authors: Tamayo-Carabaño Daniella , DeBourio-Allona Marta Martínez , Landaeta-Kancev Laura , Martínez-Dhier Luis
Published: June 2024

We present the case of a 55-year-old woman with Follicular Lymphoma, with basal 18F-FDG-PET/TC showing supra and infradiaphragmatic lymphatic, pleural and bone involvement. Treatment with Epcoritamab + Lenalidomide + Rituximab was iniciated with complete metabolic response (CR). Due to neutropenia, granulocyte colony-stimulating factor (G-CSF) was indicated on 02/22/23 for 5 days. A control PET/CT was performed on 02/23/23 with a pathological increase in metabolism in new-appearing mesenteric soft tissue lesions, suggestive of disease relapse. QT continued without changes and a PET/CT performed on 04/12/23 showed disappearance of the hypermetabolic mesenteric lesions. This suggests that it was a mesenteric panniculitis probably due to the use of G-CSF.
Support breastfeeding in premature infants in the neonatal intensive care unit
Authors: Isabel Gonzalez Gordillo Carla , Horta Carpinteyro Daniela , Zavaleta Vazquez Hector , Prian Gaudiano Alejandra
Published: June 2024

The multiple benefits of human milk in newborns are known, especially in preterm newborns by reducing the rates of neonatal sepsis, necrotizing enterocolitis, retinopathy of prematurity and better results in neurodevelopment. However, rates of exclusive breast milk use remain low. To achieve higher percentages of successful breastfeeding, strategies must be applied from the NICU, such as expressed within the first 6 hours of life, skin-to-skin contact and administration of colostrum in the cheeks, all well, in order to have sufficient volume of breast milk since this is the main barrier they face, not having enough milk. There are very few studies that evaluate when to initiate suctions directly to the maternal breast, using the empty breast as non-nutritive suction could improve the performance of VLBW to the maternal breast.
PROSPECTS OF THE USE OF MELATONIN IN RADIATION THERAPY
Authors:   RE Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine, Makovetska L.I. , Domina E.A. ,   RE Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine
Published: June 2024

Summary. Radiation therapy (RT) plays a key role in the treatment of malignant tumor diseases in the majority of cancer patients. Unfortunately, despite the improvement of RT methods and tools (in particular, its conformal strategy) and modern methods of dosimetry, RT has a harmful effect not only on the tumor, but also on normal tissues surrounding the tumor. In some cases, this leads to the development of radiation reactions and complications, the treatment of which is a long, sometimes ineffective process. One of the strategies to prevent or reduce these complications is the use of natural radioprotectors, among which the pineal hormone melatonin deserves attention. It is a powerful antioxidant with immunoregulatory properties that can reduce toxicity caused by ionizing radiation (IR) in various organs. These effects are mediated by the modulatory effects of melatonin at different levels of tissue response to IR. The most important are the effects on the DNA repair system, antioxidant enzymes, immune cells, cytokine secretion, transcription factors and protein kinases. The data highlighted in this review indicate that melatonin has great potential to prevent the side effects of RT and its inclusion as an adjuvant in RT would enable the use of higher radiation doses in treatment. In addition, due to the antitumor and radiosensitizing properties of melatonin, its use can increase tumor damage. Therefore, melatonin is a promising radioprotective agent of normal tissues surrounding the tumor with the effect of increasing the therapeutic efficiency/toxicity ratio of chemoradiation treatment of patients.
EXPRESSION PATTERNS OF CD90, CD117, CD123, AND CD147 IN CONTINUOUS CELL LINES OF HUMAN MATURE B-CELL TUMORS
Authors:   R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine, Kyiv, Ukraine, Zavelevich M.P. , Shlapatska L.M. ,   R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine, Kyiv, Ukraine, Philchenkov A.A. ,   R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine, Kyiv, Ukraine
Published: June 2024

Summary. Aim: to analyze expression patterns of CD90, CD117, CD123, and CD147 in vitro in different continuous lines of human mature B-cell neoplasms. Objects and methods: expression patterns of the surface antigens on cells of the continuous lines of Burkitt lymphoma (Namalwa and BJAB), Hodgkin lymphoma (КМ-Н2), and follicular lymphoma (Car-1) were analyzed by flow cytometry with monoclonal antibodies against CD90, CD117, CD123, and CD147. Results: BJAB and Namalwa cells did not express CD90 and CD123, while a small fraction of cells (less than 2%) was CD117-positive. КМ-Н2 and Сar-1 cells did not express any of three above mentioned antigens. The percentage of CD147-positive cells in continuous lines of human mature B-cell neoplasms amounted to 80–100%. Conclusions: CD117 expression in cell populations of Burkitt lymphoma continuous cell lines is rather rare. CD90 and CD123 are not expressed in all cell lines of human mature B-cell neoplasms under study. At the same time, ubiquitous pattern of CD147 has been evident.
INDIVIDUALIZATION OF NEOADJUVANT THERAPY IN THE TRATMENT OF PATIENTS WITH LOCALLY ADVANCED RECTAL CANCER
Authors:   Precarpathian Clinical Oncology Center, Partykevuch Yu.d. ,   Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Kryzhanivska A.E. ,   Precarpathian Clinical Oncology Center,   Ivano-Frankivsk National Medical University, Ivano-Frankivsk
Published: June 2024

Summary. Aim: to increase the effectiveness of combined treatment of patients with local advanced rectal cancer by individualizing neoadjuvant therapy and prevention of surgical complications and relapses. Objects and methods: the analysis of the results of treatment of 71 patients of rectal cancer, who received treatment in the KNP “Precarpathian Clinical Oncological Center of the Ivano-Frankivsk Regional Council” in the period 2016-2021. The study includes patients with uncomplicated local advanced rectum cancer. An analysis of the immediate and distant results of treatment of patients was carried out using neural network technology (PyTorch software). Results: it is determined that the complication of the surgical stage of treatment was in 16 patients under study. The total 3-year survival of patients with stage II-III cancer without complications of the surgical stage of treatment was 92.5%, and the total 5-year – 84%. For patients, with the existing complications, 3-year total survival was 79.5%, 5-year – 68.0%. Only with the help of mathematical analysis methods, taking into account the factors of the prognosis, you can choose the most optimal method of treatment of each particular patient. The proposed methodology for the use of neural networks was to serve the following steps: selection of many informative parameters, guided by target parameters, correlation and regression analysis. The points of view of accuracy of determining them and the target parameters and the possibility of their measurement, formulation of the method. Conclusion: neural networks were applied and informative criteria were selected for choosing the optimal variant of the neoadjuvant stage of treatment of patients with stage II-III rectal cancer, which was confirmed by their high accuracy of 80–95%.
INFLUENCE OF THE METABOLIC SYNDROME ON THE QUALITY AND LIFETIME OF PROSTATE CANCER PATIENTS WITH THE DEVELOPMENT OF BONE MEATSTASES
Authors:   National Cancer Institute of Ukraine, Stakhovskyi E.O. , Tymoshenko A. ,   National Cancer Institute of Ukraine,   R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine, Kyiv, Ukraine, Chekhun V. ,   R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS of Ukraine, Kyiv, Ukraine
Published: June 2024

Summary. Aim: to determine the quality of life, progression-free (PFS) and overall survival (OS) of patients with localized prostate cancer (PC) with existing metabolic syndrome (MS) and the development of bone metastases (BM) after radical prostatectomy (RP). Objects and methods: а retrospective clinical study diagnosed in 35 patients with localized PC and development of BM. Patients with a moderate (Grade group 2.3) and high (Grade group 4.5) risk of disease progression are divided into subgroups based on the presence and absence of MS. Analyzed indicators of recurrence-free and overall survival; the quality of life of patients was assessed using the QLQ-C30 questionnaire. Results: among 35 study participants after RP with the development of BM – 27 (77.1%) have MS, 8 (22.9%) haven’t features of MS. MS was found in 25.9% of patients with GG 2.3 and 74.1% of GG 4.5; the absence of MS was observed in 62.5 and 37.5% of patients, respectively. The median progression-free survival of patients with РС GG 2.3 and existing MS was 13.3% lower compared to the rate of patients without MS; in patients with PС GG 4.5 – by 10.5%. They also noted a decrease in the median overall survival of patients with MS compared to the rate of patients without MS by 6.4 (GG 2.3) and by 23.9% (GG 4.5). The data of the study demonstrate a decrease in the general health status of patients before RP and at the time of development of BM with existing MS by 27.6%, without MS by 5.5%. Decrease in quality-of-life indicators was noted in the following indicators: social status, fatigue, lack of appetite and the presence of financial difficulties. Conclusion: the investigation analysis showed that presence of metabolic syndrome influence on decreasing quality of life, progression-free survival and overall survival rates in patients with prostate cancer.
INTRA-PERITONEAL METASTASES AND OSTEOPOKILOSIS IN BREAST CANCER PATIENT (CLINICAL OBSERVATION)
Authors:   I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine, Ternopil, Ukraine, Galaychuk I.Y. , Karashivska O.S. ,   I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine, Ternopil, Ukraine, Drosyk M.M. ,   I. Horbachevsky Ternopil National Medical University of the Ministry of Health of Ukraine, Ternopil, Ukraine
Published: June 2024

Summary. The publication presents a clinical case of a 6-year (2018-2023) follow-up of a patient with stage IIB estrogen receptor positive/HER-2 negative breast cancer, in whom osteopoikilosis and peritoneal metastases were simultaneously diagnosed during the initial CT examination. Thanks to chemo-hormonal-radiation therapy, it was possible to achieve the first remission of the disease, which lasted three years. Prolongation of the disease was manifested by intraperitoneal recurrence of breast cancer, which was proven morphologically after cytoreductive surgery – panhysterectomy with omentectomy. Subsequent adjuvant cycles of chemotherapy had a short-lived effect. A visceral crisis, as a further progression of the disease, forced a change in the approach to the choice of treatment. Timely determination of sensitivity to cytostatics on the basis of miRNA analysis of the patient’s blood serum allowed to conduct targeted polychemotherapy with the achievement of a complete clinical and visual (CT) response, and to put the disease into a second long-term remission.
Ukrainian book influencers of thematic telegram channels from the perspective of influencer marketing
Authors: Simashova Anastasiia
Published: June 2024

The article examines the peculiarities of the functioning of author's book blogs in the Ukrainian segment of Telegram. The author argues that writing reviews by readers on a social network has long been a much larger phenomenon than reader promotion of books, but is an expression of the global phenomenon of online influencer marketing. It is proposed to adopt the term "book influencer" as a generally accepted international term for book influencers. The study analyses Ukrainian author's book blogs on Telegram and identifies 17 most popular ones by the number of subscribers. The article focuses on the peculiarities of bloggers' public identity, in particular, in the selection of content and the use of labelling for posts. It is proved that the main characteristic of the public identity of book influencers is reading as a lifestyle. Some of the latest strategies for engaging the audience are described, in particular, the activation of subscribers using the military-patriotic theme. 
It is found that book bloggers do not act on the basis of anonymity, but are interested in developing their own brand and creating social capital. posting posts on a commercial basis, and cooperation with publishers is not always on a barter basis. It has been found that most of the blogs we analysed have labelled advertising (11 out of 17), however, only a few bloggers openly state the terms of advertising.
It is noted that in addition to the marketing function, book telegram channels have a value-oriented function for their audience. It is determined that book influencers are now defending the Ukrainian book and Ukrainian book publishing, and condemning Russian literature as part of the identity of the aggressor country in the Russian-Ukrainian war.
Louro
Authors: Mazocco Letícia , Chagas Patrícia , Bisognin Garlet Tanea Maria
Published: June 2024

Conforme Dioscórides, na mitologia grega, o louro foi consagrado ao deus Apolo pelos romanos, que coroavam todos os imperadores de Roma com uma coroa feita de louro. Segundo histórias romanas, uma águia, enviada de Júpiter, deixou cair no colo de Drusilla, mulher de Augusto, uma galinha muito branca, a qual levava no bico um raminho de louro carregado de bagas muito perfumadas, que depois de plantadas se multiplicaram em abundância (Font Quer, 1978). Antigamente, se coroavam também todos os vencedores e, assim como a oliveira, era sinal de paz. O louro significava sempre sinal de vitória (Font Quer, 1978). O termo “laureado” foi adotado pelos romanos em alusão à coroa de louro usada nas premiações e originou a expressão os “louros da vitória”. Para os antigos gregos, era considerado um símbolo de glória e imortalidade (Panizza, 1997). Ainda hoje, as folhas de louro em forma de grinalda são colocadas na cabeça das pessoas como um símbolo de vitória para atletas olímpicos, poetas, estudantes e heróis militares (Chmit et al., 2014).
HISTOLOGICAL CHANGES IN VEINED RAPA WHELK MUSCLES (RAPANA VENOSA) AFTER FROZEN STORAGЕ
Authors: M. Strateva  , D. Stratev  , G. Zhelyazkov
Published: June 2024

PURPOSE: The objective of this study was to establish the effect of freezing on the histological structure of veined rapa whelk (Rapana venosa).
METHODS: Two hundred veined rapa whelks were collected from the Bulgarian Black Sea coast. Forty veined rapa whelks were subjected to histological analysis in the fresh state, while the remaining 160 veined rapa whelks were divided into 4 groups and frozen in a conventional freezer at -18ºС for 3, 6, 9 and 12 months, respectively.
RESULTS: The histological assessment revealed irreversible damages in the entire structure. The observed changes were the smallest after 3 months and the greatest after 12 months of frozen storage.
CONCLUSIONS: The histological finding can be used to distinguish fresh from frozen and thawed veined rapa whelks when making an official control.
A comparison of the results of old-generation (MEL 60) and new-generation (SCHWIND AMARIS) refractive excimer laser treatments
Authors: Dió M. , Molnár Sz. , Szekrényesi Cs. , Halmai B. , Takács J. , Nagy Z.Z.
Published: June 2024

Purpose

The present study compares the efficacy of refractive surgery using third-generation and sixth-generation laser vision correction procedures in terms of postoperative visual acuity. The goal of the authors was to determine whether advances in laser technology had improved patients' uncorrected visual acuity, as measured at six-month follow-ups.

Materials/Methods

Results were reported from one of Europe's leading laser eye clinics, which has performed an outstandingly high number of treatments (over 100,000). The results of the clinic's first 10,000 treatments and most recent 10,000 treatments were evaluated.

Results

The analysis was performed by treated dioptric range and age group. The raw six-month visual acuity results show a statistically significant improvement over the last 10,000 interventions. The treatments resulted in significant improvements in all groups compared to the previous technology. With the new devices, visual acuity increased to above 1.0 in young myopes. The best results were seen in patients between 18 and 45 years of age, in the dioptric range between −1.0 D and −6.0 D.

Conclusions

It can be concluded that advances in technology improved refractive outcomes in all patient groups. This conclusion has excellent reliability and predictability due to the particularly high number of cases.
The influence of different stress factors on the production and quality of sheep milk
Authors:   University of Zagreb, Faculty of Agriculture, Department of Animal Science and Tehnology, Svetosimunska cesta 25, 10000 Zagreb, Croatia, Mioč Boro
Published: June 2024

Around 10.5 million tonnes of sheep milk are produced worldwide, and around 3.1 million tonnes in Europe. In Europe, sheep milk production has stagnated slightly in recent years and currently accounts for around 1/3 of the global production. Due to its high content of dry matter, milk fat, total protein and casein, sheep milk is an excellent raw material for cheese production. Milk processing and cheese making are not only economically important, but also part of the cultural heritage based on a long tradition, often taking place in rural and less developed areas. Milk production and quality are very complex and are influenced by numerous factors, the most important of which are breed, feeding and body condition, parity and stage of lactation, milking and udder health, and environmental factors. In addition, different types of stress such as heat stress, nutritional stress, weaning stress, shearing stress, stress of regrouping, etc. have a significant impact on the welfare and health of the sheep as well as on the quantity of milk produced, its chemical composition, processing characteristics and the economic efficiency of the flock. In recent years, due to climate change, there has been an increasing number of studies on the effects of heat stress on the reproductive and production characteristics of sheep, as well as on their welfare and health. In addition, heat stress is often associated to the feed and the lack of water. The effects of stress are particularly pronounced in extensive sheep farming and milk production, which are prevalent in sheep farming. The aim of this paper is to describe the effects of the main types of stress on the quantity and chemical composition of sheep milk and on animal welfare.
Quality and healthy aspects of Lider cheese at different stages of ripening
Authors:   University of Belgrade, Faculty of Agriculture, Nemanjina 6, 11080 Zemun, Serbia, Barać Miroljub
Published: June 2024

Lider cheese is a commercial full- fat semi-hard cheese produced from pasteurized goat`s milk in mountain area of Nikšić, Montenegro. The aim of this paper is to characterize the change of protein and fatty acid profiles, mineral content and antioxidant potential during the period of one month of its ripening. Proteolysis was monitored using electrophoresis of total extracts and water-soluble fractions under reducing conditions. Fatty acid profiles were determined by gas chromatography whereas the mineral content of cheese at different stage of ripening was determined by Inductively coupled plasma - optical emission spectrometry (ICP-OES) for macroelements and Inductively coupled plasma mass spectrometry (ICP-MS) for microelements, respectively. One month of ripening of Lider cheese is characterized by a relatively slow proteolysis which can be attributed to intensive lose of moisture, by the increase in desirable fatty acid content and consequently by the improvement of fatty acid healthy indices. After 30 days of ripening, mainly due to the degradation of αs-CN, the WSN/ TN and TCA/TN contents increased from 4.69 % to 6.06 % and 1.15 % to 1.90 %, respectively. One- month-old cheese had improved indexes of lipid quality as well as improved reducing power and ability to scavenge free radicals. Ripening did not affect mineral content of cheese if it is expressed on dry matter basis. According to obtained results, the optimal ripening period of Lider cheese is 15 days.
S-layer proteins in microencapsulated freeze-dried probiotic Levilactobacillus brevis strains
Authors:   University of Zagreb Faculty of Food Technology and Biotechnology, Laboratory for Antibiotic, Enzyme, Probiotic and Starter Culture Technologies, Pierottijeva 6, 10000 Zagreb, Croatia, Čuljak Nina
Published: June 2024

The presence of surface (S)-layer proteins as a rare property of lactic acid bacteria plays an important role in the expression of the probiotic properties of the producer strain and protects the cells from unfavourable environmental conditions. Therefore, the aim of this work was to evaluate the role of S-layer proteins of four Levilactobacillus brevis MB1, MB2, MB13, and MB20 strains, previously isolated from human milk. The results showed better survival under simulated gastrointestinal tract (GIT) conditions and better adhesion to Caco-2 cells, achieved when S-proteins were present on the surface of the examined probiotic Levilactobacillus brevis strains. Free cells and cells microencapsulated in alginate, with or without galactooligosaccharides (GOS) and fructooligosaccharides (FOS), survived in high numbers during freeze-drying and one-month storage at 4 °C, as well as during exposure to simulated GIT conditions (>108 CFU/g), thus fulfilling the primary technological criterion for the selection of probiotic strains. Higher survival of freeze-drying of encapsulated cells than free cells, can be attributed to the protective effect of alginate, GOS and FOS as prebiotic agents. However, GOS was more protective than FOS in maintaining the viability of microencapsulated Levilactobacillus brevis MB1, MB2, MB13 and MB20 cells in alginate during storage and under the harsh conditions of GIT and freeze-drying.
Hybridization of an s-wave impurity with graphene lattice
Authors: Nghiem Hoa , Pham Lam , Nguyen Linh , Đặng Hùng Thế
Published: June 2024

Hybridization function is a quantity characterizing electron hoppings between an impurity and a host material in which the impurity resides, a full understandinging of it is crucial for studying correlation effects in various impurity problems. This work studies the hybridization function for the Anderson impurity model describing a single-orbital impurity on a honeycomb lattice simulating graphene and presents a calculation approach to obtain this function at low energy. Within this approach, the general form of the hybridization function in graphene is presented and analytical expressions of low-energy hybridization spectrum are obtained. The results quantitatively match numerical solutions for different impurity positions on the lattice. The effect of the low-energy hybridization spectrum and the capability to predict the correlated effects of the impurity problem are discussed thoroughly, suggesting that different types of pseudogap Kondo effect may occur at different impurity positions.
Learning Mathematics by Designing, Programming, and Investigating with Interactive, Dynamic Computer-based Objects
Authors: Marshall Neil , Buteau Chantal
Published: June 2024

As part of their undergraduate mathematics curriculum, students at Brock University learn to create and use computer-based tools with dynamic, visual interfaces, called Exploratory Objects, developed for the purpose of conducting pure or applied mathematical investigations. A student’s
Development Process Model of creating and using an Exploratory Object provides insights on the kinds of activities emerging from their creation and use. We propose to discuss Exploratory Objects by examining them, as a learning activity, across a literature review involving four educational
areas: learning mathematics by use of simulation, learning mathematics by programming, learning experimental mathematics, and inquiry-based learning in science and mathematics education. Through this contextualisation, a refinement of the Development Process Model is proposed. Our results
suggest that the learning activity of creating and using Exploratory Object is closely related to that of using microworlds.
Atrial Fibrillation and Chronic Heart Failure: Common Pathogenetic Pathways, Approaches to Treatment, Potential for Application of Artificial Intelligence
Authors: Utsumueva Madina D. , Mironov Nikolay Yu. , Golitsyn Sergey P. , Dolgusheva Yulia A. , Beregovykh Valery V. , Schimanowsky Nikolay L.
Published: June 2024

Atrial fibrillation (AFib) and chronic heart failure (CHF) are frequently encountered cardiovascular conditions that share common causes and tend to coexist in some patients. Such coexistence represents a major issue due to augmentation of symptoms severity, rapid deterioration, and poor prognosis. Management of patients with AFib and CHF is challenging due to limitations in pharmacotherapy and decreased efficacy of cardiac interventions. In this review we focus on crucial pathogenic components of AFib and CHF coexistence, key treatment approaches and discuss potential for implementation of artificial intelligence.
Clinical Significance of Monogenic Mutations in the Euploid Embryo Genome Associated with Miscarriage
Authors: Kudryavtseva Elena V. , Kovtun Olga P. , Kovalev Vladislav V.
Published: June 2024

Background. Chromosomal abnormalities of the embryo are the most common cause of miscarriage. However, at least 100 thousand cases of repeated pregnancy losses occur annually in the world, in which cytogenetic methods determine the chromosome euploid set in the abortive material. One of the causes of miscarriage is probably the loss of function of certain genes. It is assumed that the detection of genetic factors determining the etiology of pregnancy loss can help to develop personalized methods of diagnosis and preconception care in cases where the classical approach with chromosomal analysis is insufficient.
Aims — to analyze the experience of genetic testing of euploid embryos and identify the most significant genetic variants in miscarriage.
Methods. A search was conducted for sources of scientific literature in the PubMed and RSCI (elibrary) databases. The search for full-text articles was carried out on the websites of journals and using the ResearchGate database. The review included articles published in peer-reviewed scientific publications in the period from 2013 to 2023.
Results. Studies conducted on animals and analysis of human embryos during miscarriage have revealed a list of genes which loss of function may be associated with embryolethality. Analyzing the data of the scientific literature, we concluded that a number of genes potentially related to miscarriage can lead to various diseases in the postnatal period.
Conclusions. Scientific research aimed at finding monogenic causes of miscarriage is of great scientific and practical importance, since it can contribute to improving the algorithm of examination and pre-conception preparation of married couples with a history of pregnancy loss.
Letter from the Editor
Authors:   Portland State University, Yanase Lauren
Published: June 2024

Letter from Lauren Yanase, Editor-in-Chief, offering a brief background of this issue of Anthós and thanking people who have been instrumental in its publication.
Multiple copy number variation in a patient with Kleefstra syndrome
Authors: Lee Thomas Nohama , Rechetello Henrique El Laden , Lima Júnior João Batista De Arêa , Cornelio João Pedro Fagoti Ferraz , Pegoraro Naiara Bozza , Raskin Salmo , Mikami Liya Regina
Published: June 2024

ABSTRACT Objective: To report a rare case of a patient with a molecular diagnosis of Kleefstra syndrome (KS) who has four other chromosomal alterations involving pathogenic variants. Case description: Male patient, two years old, with global delay, including in neuropsychomotor development, ocular hypertelorism, broad forehead, brachycephaly, hypotonia, ligament laxity, unilateral single palmar crease and arachnoid cyst. The microarray-based comparative genomic hybridization (a-CGH) identified copy number variations (CNVs) in five regions: 9q34.3, 6p22.1, Yq11.223, Yp11.23, and 2q24.1. The heterozygous microdeletion in 9q34.3 involving the EHMT1 gene confirms the diagnosis of KS. Comments: The presence of pathogenic CNVs and/or those of uncertain significance, located on chromosomes 2, 6 and Y, may be contributing to a variability in the patient's clinical condition (arachnoid cyst, single palmar fold and ligament laxity), compared to other individuals with only KS genetic alteration, making the dignosis of the disease harder.
Cuentos para la inclusión y el cambio de actitudes hacia la diversidad
Authors: Belmonte Maria Luisa , Fernández Noelia , Mirete Ana Belén
Published: June 2024

RESUMEN La realidad presente en el horizonte educativo aún continúa perpetrada por situaciones de no inclusión para alumnado con diversidad funcional. El cuento se presenta como herramienta psicoterapéutica muy adecuada para trabajar las emociones. A través del cuento se perciben mejor las diferentes situaciones sociales, donde aún existen barreras y prejuicios hacia distintos colectivos con discapacidad. Este trabajo constata una experiencia de 52 estudiantes, con diseño cuasiexperimental con pretest, postest y grupo control, que basa su tratamiento en el uso de cuentos. El instrumento VADA fue cumplimentado antes del tratamiento y transcurridos tres meses. A la luz de los resultados se concluye que, si bien en edades tempranas las actitudes hacia la diversidad no presentan grandes prejuicios, el cuento es un recurso óptimo para su mejora. En este sentido, el diseño de proyectos centrados en cuentos supone un paso hacia delante en la construcción de una escuela y sociedad más inclusiva.
A IMPLANTAÇÃO DA CURRICULARIZAÇÃO DA EXTENSÃO NO INSTITUTO FEDERAL DE SÃO PAULO: A PERSPECTIVA DOS DOCENTES
Authors: Fuini Lucas Labigalini
Published: June 2024

A atividade extensionista pode ser considerada um dos eixos da existência dos Institutos Federais, sobretudo no esforço de aproximação das práticas e saberes institucionais com as demandas das comunidades do entorno dos campi. Posto isto, este artigo visa apresentar e discutir a política de Curricularização da Extensão (CE) atualmente em voga na Rede Federal de Educação Profissional, Científica e Tecnológica, em específico no Instituto Federal de São Paulo, considerando o ponto de vista do corpo docente sobre esse processo. Desse modo, este texto se apoia em metodologia de pesquisa bibliográfico- documental e de campo, com coleta de dados primários, em um estudo de tipo qualitativo que buscará compreender o processo de implantação da CE, suas vantagens e desafios.