bluuebunny/crossref_metadata_2025 huggingface dataset:
Unique progerin C-terminal peptide ameliorates Hutchinson–Gilford progeria syndrome phenotype by rescuing BUBR1
Authors: Zhang Na , Hu Qianying , Sui Tingting , Fu Lu , Zhang Xinglin , Wang Yu , Zhu Xiaojuan , Huang Baiqu , Lu Jun , Li Zhanjun , Zhang Yu
Published: February 2023

An accumulating body of evidence indicates an association between mitotic defects and the aging process in Hutchinson–Gilford progeria syndrome (HGPS), which is a premature aging disease caused by progerin accumulation. Here, we found that BUBR1, a core component of the spindle assembly checkpoint, was downregulated during HGPS cellular senescence. The remaining BUBR1 was anchored to the nuclear membrane by binding with the C terminus of progerin, thus further limiting the function of BUBR1. Based on this, we established a unique progerin C-terminal peptide (UPCP) that effectively blocked the binding of progerin and BUBR1 and enhanced the expression of BUBR1 by interfering with the interaction between PTBP1 and progerin. Finally, UPCP significantly inhibited HGPS cellular senescence and ameliorated progeroid phenotypes, extending the lifespan ofLmnaG609G/G609Gmice. Our findings reveal an essential role for the progerin-PTBP1-BUBR1 axis in HGPS. Therapeutics designed around UPCP may be a beneficial strategy for HGPS treatment.
The Microbes Fight Back: Antibiotic Resistance
Authors: Bowater Laura
Published: February 2023

Antibiotics are familiar drugs to us all, so familiar that we may take them for granted. They allow us to survive life-threatening infections, and allow us to protect the animals we farm for food. Many antibiotics have now become ineffective against common diseases, and there are few alternative treatments to replace them. In this topical popular science book, Laura Bowater, Professor of Microbiology Education and Engagement at Norwich Medical School, considers the past, present and uncertain future of antibiotics.

This book begins by looking back at how infectious diseases, such as smallpox and the plague, were able to wreak havoc on populations before the discovery of the first antibiotics. These then revolutionised the medical world. In an engaging and accessible style, Professor Bowater takes the reader through how antibiotics are made, how bacteria are able to mutate and develop resistance and she explains why there is now a lack of new antibiotic drugs coming to market.

What will a future of continued antibiotic resistance look like? How can human activities prevent the rise of ‘superbugs'? Professor Bowater highlights the need for universal cooperation in order to tackle this global health challenge, which, if not addressed, could transport us back to the medical dark ages.
The Chemistry of Carbonyl Compounds and Derivatives
Authors: Costa Paulo , Pilli Ronaldo , Pinheiro Sergio , Bakuzis Peter
Published: February 2023

Originally published in Portuguese, this book is divided into three sections: the chemistry of aldehydes, ketones, nitriles, imines and derivatives; the chemistry of carboxylic and carbonic acids and derivatives; and the chemistry of alpha, beta-unsaturated carbonyls. The authors have merged aspects of valence bond and molecular orbital theories in order to discuss structural and physico-chemical properties and reactivity and stereochemical outcomes of the most relevant reactions for these functional groups.

The book provides representative experimental procedures for key reactions; highlights to contextualize the concepts; properties (industrial applications, biochemical significance and catalytic developments in order to cope with the major tenets of the green chemistry approach) and includes some biographical notes for the scientists who contributed to this field. It will help advanced level undergraduate and graduate students to understand and become well acquainted with the reactions of carbonyl compounds and derivatives. The integrated approach is considered an attractive feature of this book since students receive relatively little exposure to molecular orbital theory at the undergraduate level. The juxtaposition of conventional valence bond theory with molecular orbital theory fills a largely unmet pedagogical niche.
Fat Chemistry: The Science behind Obesity
Authors: Allardyce Claire S
Published: February 2023

Currently, the health of over half the adult population in the UK suffers because of fat. The UK is not alone: obesity is a global problem, but the populations of some countries are heavier than others. This book probes the chemistry of fat in our bodies, providing a unique insight into understanding obesity, and how this material becomes accumulated to cause obesity with particular emphasis on the contribution of nutrition beyond calories. It visits the current hot topic of the genetic origins of obesity and progresses through to the relatively under publicised field of epigenetics, emphasising its importance to understanding the current epidemic. Coming in the wake of the establishment of international collaborations, the book aims to quantify the extent of the contribution of nutritional deficiencies to body weight gain. Yet even before these studies begin some important links have been identified and the molecular mechanisms by which they induce obesity have been mapped. This information reveals a serious problem for the next generation, but it is expected to provide the necessary information to tackle the obesity epidemic. Based on an extensive review of scientific literature, this topical book is written in a way that is accessible to the non-specialist. Suitable for the general public, the principal focus of the book is to advance the public understanding and awareness of science through the high interest subject of obesity. However, many universities recommend public understanding of science texts to students as a means of broadening general knowledge and as a means to emphasise to students the importance of communicating their research to the public. This book will be instrumental in developing this knowledge.
Perfume in the Bible
Authors: Sell Charles
Published: February 2023

Perfume is part of the biblical text from Genesis through to Revelation, just as perfume pervades our modern life. Identifying the ingredients used in biblical times is difficult when information and meaning is lost in ancient languages. As expected, biblical perfumes were made from natural products but the range employed is surprisingly different from those of modern perfumes. The biblical ingredients are either defensive substances or products of decay, opening up an avenue of speculation as to why this is so.

Charles Sell started his research into this area whilst working at Givaudan, the world’s leading manufacturer of perfumes and flavours. The introductory chapter of this book gives a brief outline of the history of the Bible lands, paving the way to understanding the difficulties in identifying exactly which plant sources the original authors meant. Other chapters discuss how plants make chemicals and how the sense of smell functions. The book explores the preparation, storage and uses of perfume, both sacred and secular, and compares and contrasts biblical perfumes with their modern equivalents. It recounts some interesting biblical events involving perfume ranging from courtship through seduction to prostitution and murder. The use of beautiful images from the windows of Canterbury Cathedral, where the author is a guide, illustrate some of the people and events in the biblical accounts and enable visualization of the historical uses of perfumes.

The book is aimed at a broad audience and requires no prior specialised knowledge. The subject matter will be of interest to everyone, including chemists and general scientists, historians, those interested in perfumery, those interested in religious studies, and anyone interested in exploring chemistry in the world of art and the creative professions.
Traveling with the Atom A Scientific Guide to Europe and Beyond
Authors: Rodgers Glen E
Published: February 2023

Traveling with the Atom is a historical travel guide to the development of one of the most significant and enduring ideas in the history of humankind: the atomic concept. This history covers the notable places and landmarks commemorating this achievement, visiting homesteads, graveyards, laboratories, apartments, abbeys and castles, through picturesque rural villages and working class municipalities. From Montreal to Manchester, via some of the most elegant and romantic cities in Europe, Traveling with the Atom guides the reader on a trip through the lives and minds of the great thinkers who collectively unveiled the mystery of the atom. Fully illustrated and interspersed with intriguing and insightful notes throughout, this book is an ideal companion for the wandering scientist, their students, friends and companions or quintessential fireside reading for lovers of science and travel.
Good Chemistry: Methodological, Ethical, and Social Dimensions
Authors: Mehlich Jan
Published: February 2023

Practicing chemists face a number of ethical considerations, from issues of attribution of authorship through the potential environmental impact of a new process to the decision to work on chemicals that could be weaponised. By keeping ethical considerations in mind when working, chemists can build their own credibility, contribute to public trust in the chemical sciences and do science that benefits the world.

Divided into three parts, methodological aspects, research ethics, and social and environmental implications, Good Chemistry introduces tools and concepts to help chemists recognise the ethical and social dimensions of their own work and act appropriately.

Written to support chemistry students in their studies this book includes practice questions and examples of relevant situations to help students engage with the subject and prepare for their professional life in academia, industry, or public service.
Stimuli-Responsive Materials: From Molecules to Nature Mimicking Materials Design
Authors: Urban Marek W
Published: February 2023

The ability for a material to change properties in response to external stimuli is an attractive feature for numerous applications and as such stimuli responsive materials are gaining attention across many different fields. This book introduces the concepts of stimuli-responsiveness, including the fundamental materials properties required for design. It provides readers with comprehensive scientific principles and developments of stimuli responsive materials, as well as the recent technological advances. Written by a renowned expert in the field, this book is suitable for anyone interested in stimuli responsive materials working in polymers, biochemistry, biotechnology and materials science.
Practical Volumetric Analysis
Authors: McPherson Peter
Published: February 2023

Proficiency in volumetric analysis is a key skill for chemists in research and industry. This work seeks to ‘modernise’ approaches to volumetric analysis, by relating practical work to vocationally-relevant topics, whilst maintaining the rigor required for satisfactory performance in practical examinations. Written by someone who has experienced both teaching and working as a research chemist, this up to date textbook on practical volumetric analysis will provide the theoretical chemistry associated with volumetric analysis supported by a selection of practicals. There will also be suggestions for a number of investigations which could form the basis of project-based learning or coursework, particularly for those pursing vocational science courses.

Section 1 will consist of three theory chapters, covering preliminary concepts (fundamentals of chemistry, essential quantitative chemistry and concepts of statistics). Section 2 will be divided into four chapters, based on the four main divisions of volumetric analysis (acid-base titrimetry, redox titrimetry, precipitation titrimetry and complexometric titrimetry). Each chapter in this section will start with a review of essential theory, with worked examples and illustrations where appropriate, and end with a selection of laboratory practicals. Each chapter will also contain a number of open-ended investigations, for use in project-based learning or coursework. Section 3 will address more advanced topics and be divided into four chapters (volumetric analysis in industry, further statistical concepts, mathematics of titrimetry and advanced titrimetry). Practical work and suggestions for further reading will be included where appropriate.

Practical Volumetric Analysis is suitable for students taking modules in introductory chemistry and analytical chemistry on undergraduate degree courses as well as providing guidance to non-specialists teaching chemistry.
A paper-based colorimetric method for monitoring of lithium therapeutic levels
Authors: Sheikh Mahsa , Qassem Meha , Kyriacou Panicos A.
Published: February 2023

Paper-based colorimetric detection of lithium therapeutic levels in the management of bipolar disorder.
A rapid discriminative hydrogen–deuterium exchange and LC-HRMS/MS strategy for primary and higher order structural mapping of therapeutic proteins: a case study using filgrastim
Authors: Thakkar Harsh , Eerla Rameswari , Sharma Lokesh , Shah Ravi P.
Published: February 2023

Amalgamation of hydrogen–deuterium exchange and mass spectrometer for rapid determination of higher order structural differences in therapeutic proteins.
High sensitivity (zeptomole) detection of BODIPY-labelled heparan sulfate (HS) disaccharides by ion-paired RP-HPLC and LIF detection enables analysis of HS from mosquito midguts
Authors: Maciej-Hulme Marissa L. , Leprince Anaëlle C. N. , Lavin Andre , Guimond Scott E. , Turnbull Jeremy E. , Pelletier Julien , Yates Edwin A. , Powell Andrew K. , Skidmore Mark A.
Published: February 2023

Ultra-sensitive disaccharide compositional analysis of heparin and heparan sulfate facilitated by ion-paired, reversed phase HPLC coupled with laser-induced fluorescence detection.
Large changes in hydricity as a function of charge and not metal in (PNP)M–H (de)hydrogenation catalysts that undergo metal–ligand cooperativity
Authors: Schlenker Kevin , Casselman Lillee K. , VanderLinden Ryan T. , Saouma Caroline T.
Published: February 2023

Ligand pKa and metal hydricity scale with one another in (de)hydrogenation catalysts that undergo metal–ligand cooperativity, irrespective of metal or ligand identity. Anionic hydrides are significantly more hydridic than their neutral counterparts.
Energy bands matched photocatalysis enhancement based on viologen derivatives electron-transfer-mediator
Authors: Niu Fang , Zhu Jia-Lin , Ding Yong , Tao Li-Ming , Jin Jun
Published: February 2023

Viologen derivatives with non-conjugated substituent groups sharply promoted photocatalytic HER performance under o-CTF photocatalysis, while viologen derivatives with conjugated substituent groups decreased the photocatalytic HER rate.
Pd/N, S co-doped activated carbon as a highly-efficient catalyst for the one-pot synthesis of meropenem
Authors: Li Yuefeng , Xiong Fengmei , Yan Jiangmei , Wang Zhaowen , Hong Tao , Zhang Zhixiang , Li Yu , Jing Xinli
Published: February 2023

Pd/N, S co-doped activated carbon with 3 wt% sulfur exhibited higher Pd dispersion, smaller Pd particle size, and the highest Pd2+ content, which exhibited substantially enhanced activity for the one-pot synthesis of meropenem over all Pd/C catalysts.
Elucidating the exchange interactions in a {GdIIICuII4} propellor
Authors: Heras Ojea María José , Wilson Claire , Cirera Jordi , Oshio Hiroki , Ruiz Eliseo , Murrie Mark
Published: February 2023

In [GdCu4(H4L)4]3+ the geometrical arrangement of the Cu(ii) centres, defined by the bis–tris propane ligands, controls the exchange interactions.
Alkyl-phenanthrenes in early life stage fish: differential toxicity in Atlantic haddock (Melanogrammus aeglefinus) embryos
Authors: Donald Carey E. , Nakken Charlotte L. , Sørhus Elin , Perrichon Prescilla , Jørgensen Kåre B. , Bjelland Hege K. , Stølen Christine , Kancherla Sindhu , Mayer Philipp , Meier Sonnich
Published: February 2023

Comparative developmental toxicity at the limit of solubility appears unrelated to the position of alkyl substitution. Toxic effects are like crude oil exposures, however much higher doses of the individual compounds are needed.
Formation of oil-particle aggregates with motor oil and kaolinite clay in cold and warm freshwater
Authors: Fahmi Alali Abdulrhman , Wang Shu , Zhu Zhenduo , Atkinson Joseph
Published: February 2023

This study is the first of its kind to examine experimentally and computationally the formation of oil particle aggregates (OPAs) with motor oils as a function of oil viscosity, mixing intensity, and water temperature in freshwater.
Magnetic copper hexacyanoferrate core–shell nanoparticles for effective cesium removal from aqueous solutions
Authors: Wang Yihui , Li Fenghua , Mao Jiali , Wang Xiaomin , Shao Yong , Yuan Junhua
Published: February 2023

Selective and efficient removal of Cs+ ion by CuHCF@Fe3O4 nanoparticles and their regeneration can be controlled by modulating the redox state of CuHCF on Fe3O4 nanoparticles. The CuHCF@Fe3O4 nanoparticles can be easily recollected by magnet.
Simulating long term discolouration behaviour in large diameter trunk mains
Authors: Sunny Iftekhar , Husband Stewart , Boxall Joby
Published: February 2023

Tracking accumulation and mobilisation behaviour of pipe wall material layers shows the Variable Condition Discolouration Model (VCDM) capable of simulating long term hydraulic induced discolouration behaviour in drinking water distribution systems.
Engineering extracellular vesicles derived from macrophages for tumor therapy: a review
Authors: Yan Ying , Zhang He , Wei Shiqi , Xie Weimin , Chen Ying , Yang Huaming
Published: February 2023

Compared to cellular immunotherapy, engineering macrophage-derived EVs which carry nanoparticles, drugs, proteins, nucleic acids etc. can target tumor cells to improve biosafety and treatment efficacy.
Ferroelectric Hf0.5Zr0.5O2 films with improved endurance obtained through low temperature epitaxial growth on seed layers
Authors: Song Tingfeng , Bachelet Romain , Saint-Girons Guillaume , Fina Ignasi , Sánchez Florencio
Published: February 2023

A seed layer with a thickness of about 2 nm allows reduction of the threshold temperature for epitaxy of Hf0.5Zr0.5O2 films at least by 200 °C. Films deposited at low temperatures on seed layers show reduced ferroelectric fatigue and improved endurance.
Doping and pretreatment optimized the adsorption of *OCHO on bismuth for the electrocatalytic reduction of CO2to formate
Authors: Tian Meng , Wu Shanshan , Hu Yang , Mu Zhaori , Li Zhi , Hou Yichao , Xi Pinxian , Yan Chun-Hua
Published: February 2023

A Cu-doped bismuth catalyst with a unique morphology and electronic structure was constructed by adjusting thein situreconstruction environment. Copper doping promoted the adsorption of CO2and reduced the formation barrier of intermediate *OCHO.
Shape programmable T1–T2 dual-mode MRI nanoprobes for cancer theranostics
Authors: Liu Menghan , Yuan Jia , Wang Gongzheng , Ni Nengyi , Lv Qian , Liu Shuangqing , Gong Yufang , Zhao Xinya , Wang Ximing , Sun Xiao
Published: February 2023

Herein, an overview of the research progress in various shaped nanomaterials for dual-mode MRI was carried out. In addition, the combination of the nanoprobes with advanced therapeutic strategies and possible challenges are systematically discussed.
Self-assembly of β-cyclodextrin-pillar[5]arene molecules into supramolecular nanoassemblies: morphology control by stimulus responsiveness and host–guest interactions
Authors: Lu Jie , Deng Yingying , Liu Peng , Han Qingqing , Jin Long Yi
Published: February 2023

Various supramolecular nanoassemblies were constructed by amphiphilic β-cyclodextrin-pillar[5]arene molecules through modifying the molecular structures of the linker units and the formation of the host–guest molecules.
Lead accumulation and biochemical responses in Rhus chinensis Mill to the addition of organic acids in lead contaminated soils
Authors: Shi Xiang , Wang Shufeng , He Wenxiang , Wang Yangdong
Published: February 2023

Adding organic acid is an effective approach to assist phytoremediation.
Deep learning assisted holography microscopy for in-flow enumeration of tumor cells in blood
Authors: Gangadhar Anirudh , Sari-Sarraf Hamed , Vanapalli Siva A.
Published: February 2023

Currently, detection of circulating tumor cells (CTCs) in cancer patient blood samples relies on immunostaining, which does not provide access to live CTCs, limiting the breadth of CTC-based applications.
Marine organisms as potential sources of natural products for the prevention and treatment of malaria
Authors: Negm Walaa A. , Ezzat Shahira M. , Zayed Ahmed
Published: February 2023

Vector-borne diseases (VBDs) are a worldwide critical concern accounting for 17% of the estimated global burden of all infectious diseases in 2020.
Improved chemometric approach for XRF data treatment: application to the reverse glass paintings from the Lipari collection
Authors: Armetta Francesco , Saladino Maria Luisa , Martinelli Maria Clara , Vilardo Rosario , Anastasio Gianfranco , Trusso Sebastiano , Nardo Viviana Mollica , Giuffrida Dario , Ponterio Rosina Celeste
Published: February 2023

XRF data of a glass collection from Lipari Museum were processed by multivariate analysis by means of Principal Component Analysis (PCA) and Hierarchical Cluster Analysis (HCA).
Eco-friendly and efficient catalyst-free synthesis of N-sulfonylimines from sulfonamides and aldehydes: crucial role of Al2O3 as a reusable dehydrating agent
Authors: Litim Zaineb , Slimi Hanen , Ollevier Thierry , Kraïem Jamil
Published: February 2023

A green synthesis of N-sulfonylimines was developed involving the straightforward condensation of sulfonamides with aldehydes under green and catalyst-free conditions, mediated by neutral Al2O3 as an efficient and reusable dehydrating agent.
Mechanochemical solid state single electron transfer from reduced organic hydrocarbon for catalytic aryl-halide bond activation
Authors: Biswas Amit , Bhunia Anup , Mandal Swadhin K.
Published: February 2023

Under the influence of mechanical energy, a reduced organic hydrocarbon can transfer electrons in the solid-state to accomplish strong bond activation. Such activation was integrated into a catalytic cycle to design cross-coupling reactions.
Assigning 1H chemical shifts in paramagnetic mono- and bimetallic surface sites using DFT: a case study on the Union Carbide polymerization catalyst
Authors: Nobile Anna Giorgia , Trummer David , Berkson Zachariah J. , Wörle Michael , Copéret Christophe , Payard Pierre-Adrien
Published: February 2023

A cost-efficient DFT methodology was designed to calculate 1H chemical shifts of antiferromagnetically coupled metal dimeric. This method allowed us to assign the 1H chemical shifts observed for the industrial-like UC catalyst.
Cell-binding peptides on the material surface guide stem cell fate of adhesion, proliferation and differentiation
Authors: Sung Tzu-Cheng , Wang Ting , Liu Qian , Ling Qing-Dong , Subbiah Suresh Kumar , Renuka Remya Rajan , Hsu Shih-Tien , Umezawa Akihiro , Higuchi Akon
Published: February 2023

The binding of stem cells with a peptide-immobilized material surface, where several peptides are designed and conjugated on the material with multiple reactions, activates several signaling pathways that determine the stem cell fate.
Electrospinning of collagen: enzymatic and spectroscopic analyses reveal solvent-independent disruption of the triple-helical structure
Authors: Visser Dmitri , Rogg Katharina , Fuhrmann Ellena , Marzi Julia , Schenke-Layland Katja , Hartmann Hanna
Published: February 2023

Electrospun collagen mats were analyzed using circular dichroism, enzymatic digestion, SDS-PAGE, western blotting, and Raman spectroscopy and compared to heat-denaturated and electrospun collagen in HFIP.
Two-dimensional Janus monolayers Al2XYZ (X/Y/Z = S, Se, Te, X ≠ Y ≠ Z): first-principles insight into the photocatalytic and highly adjustable piezoelectric properties
Authors: Qi Chenchen , Yan Cuixia , Li Qiuyang , Yang Ting , Qiu Shi , Cai Jinming
Published: February 2023

First-principles calculations show that the photocatalytic water decomposition reaction of Janus monolayers Al2XYZ (X/Y/Z = S, Se, Te, X ≠ Y ≠ Z) can be carried out spontaneously under an applied potential. The Janus monolayers have highly adjustable piezoelectric properties.
Ultrafast fabrication of cavity-controlled perovskite-crystallites by a spin-coating method for microlasers
Authors: Guo Junhan , Li Longtao , Liu Bin , Tang Yang , Qin Liang , Deng Zhenbo , Lou Zhidong , Hu Yufeng , Teng Feng , Hou Yanbing
Published: February 2023

We have developed a rapid and antisolvent-free approach to fabricate high-quality square and octagonal MAPbBr3 microdisks. The fabricated microdisks show excellent laser performance.
Microwave-assisted pincer-ruthenium catalyzed Guerbet reaction for the upgradation of bio-ethanol to bio-butanol
Authors: Das Kanu , Kathuria Lakshay , Jasra Raksh Vir , Dhole Sunil , Kumar Akshai
Published: February 2023

Bis(benzimidazole-2-yl)pyridine based pincer-ruthenium (immobilized or otherwise) catalyzes the upgradation of feed agnostic bio-ethanol to fuel grade n-butanol at unprecedented turnovers under microwave conditions within two hours of reaction.
A family of CuI-based 1D polymers showing colorful short-lived TADF and phosphorescence induced by photo- and X-ray irradiation
Authors: Artem'ev Alexander V. , Doronina Evgeniya P. , Rakhmanova Mariana I. , Hei Xiuze , Stass Dmitri V. , Tarasova Ol'ga A. , Bagryanskaya Irina Yu. , Samsonenko Denis G. , Novikov Alexander S. , Nedolya Nina A. , Li Jing
Published: February 2023

We present 1D CuI-based polymers exhibiting remarkable short-lived TADF and phosphorescence induced by photo- or X-ray irradiation.
Revealing the electronic, optical and photocatalytic properties of PN-M2CO2 (P = Al, Ga; M = Ti, Zr, Hf) heterostructures
Authors: Munawar M. , Idrees M. , Alrebdi Tahani A. , Amin B.
Published: February 2023

Using DFT, the electronic structure, optical, and photocatalytic properties of PN (P = Ga, Al) and M2CO2 (M = Ti, Zr, Hf) monolayers and their PN-M2CO2 van der Waals heterostructures are investigated.
Strengthening the non-pre-irradiated near-infrared mechanoluminescence of CaZnOS:Nd3+ by Mn2+ coactivation for biomechanical imaging
Authors: Lei Jianxiong , Li Wei , Tang Yiqian , Cai Yiyu , Wang Shanshan , Dou Kunpeng , Zhang Jun-Cheng
Published: February 2023

Doping of Mn2+ greatly enhances the non-pre-irradiated near-infrared mechanoluminescence (NIR ML) of CaZnOS:Nd3+ by energy transfer from the host to Mn2+ to Nd3+. This effect allows the acquisition of NIR ML images with high signal-to-background ratios in biomechanical imaging.
Fast and flexible stack‐based inverse tone mapping
Authors: Zhang Ning , Ye Yuyao , Zhao Yang , Li Xufeng , Wang Ronggang
Published: February 2023

Inverse tone mapping technique is widely used to restore the lost textures from a single low dynamic range image. Recently, many stack‐based deep inverse tone mapping networks have achieved impressive results by estimating a set of multi‐exposure images from a single low dynamic range input. However, there are still some limitations. On the one hand, these methods usually set a fixed length for the estimated multi‐exposure stack, which may introduce computational redundancy or cause inaccurate results. On the other hand, they neglect that the difficulties of estimating each exposure value are different and use the identical model to increase or decrease exposure value. To solve these problems, the authors design an exposure decision network to adaptively determine the number of times the exposure of low dynamic range input should be increased or decreased. Meanwhile, the authors decouple the increasing/decreasing process into two sub‐modules, exposure adjustment and optional detail recovery, based on the characteristics of different variations of exposure values. With these improvements, this method can fast and flexibly estimate the multi‐exposure stack from a single low dynamic range image. Experiments on several datasets demonstrate the advantages of the proposed method compared to state‐of‐the‐art inverse tone mapping methods.
An activated variable parameter gradient‐based neural network for time‐variant constrained quadratic programming and its applications
Authors: Wang Guancheng , Hao Zhihao , Li Haisheng , Zhang Bob
Published: February 2023

This study proposes a novel gradient‐based neural network model with an activated variable parameter, named as the activated variable parameter gradient‐based neural network (AVPGNN) model, to solve time‐varying constrained quadratic programming (TVCQP) problems. Compared with the existing models, the AVPGNN model has the following advantages: (1) avoids the matrix inverse, which can significantly reduce the computing complexity; (2) introduces the time‐derivative of the time‐varying parameters in the TVCQP problem by adding an activated variable parameter, enabling the AVPGNN model to achieve a predictive calculation that achieves zero residual error in theory; (3) adopts the activation function to accelerate the convergence rate. To solve the TVCQP problem with the AVPGNN model, the TVCQP problem is transformed into a non‐linear equation with a non‐linear compensation problem function based on the Karush Kuhn Tucker conditions. Then, a variable parameter with an activation function is employed to design the AVPGNN model. The accuracy and convergence rate of the AVPGNN model are rigorously analysed in theory. Furthermore, numerical experiments are also executed to demonstrate the effectiveness and superiority of the proposed model. Moreover, to explore the feasibility of the AVPGNN model, applications to the motion planning of a robotic manipulator and the portfolio selection of marketed securities are illustrated.
Computation rate optimization for double‐intelligent reflecting surface aided mobile edge computing system
Authors: Yu Chao , Li Yixuan , Xie Wenwu , Zhu Peng , Peng Xin
Published: February 2023

In order to improve the performance of the mobile edge computing (MEC) system, the intelligent reflecting surface (IRS) has recently been included. This paper investigates the computation performance of an IRS‐aided MEC system, where an access point services multi‐MEC devices by utilizing two distributed IRSs to operate a partial offloading strategy. Through collaboratively constructing the cooperative passive beamforming at the two IRSs, the central processing unit (CPU) frequency, the offloading time allocation, and the transmit power of users, an optimization problem is constructed to maximize the sum computation rate of the proposed system. To tackle this non‐convex issue, the authors first illustrate that the design of passive beamforming is independent to optimize other variables and propose to solve it alternatively. Then the joint optimization problem of other parameters is proved to be a convex problem and is resolvable by adopting the Lagrange dual approach. Compared with the benchmark schemes, the simulation outcomes demonstrated that the performance of the proposed system is vastly improved by deploying two distributed IRSs.
An innovative technique for optimization and sensitivity analysis of a PV/DG/BESS based on converged Henry gas solubility optimizer: A case study
Authors: Ghadimi Noradin , Sedaghat Majid , Azar Keyvan Karamnejadi , Arandian Behdad , Fathi Gholamreza , Ghadamyari Mojtaba
Published: February 2023

The construction of hybrid power plants with renewable resources can bring significant economic benefits if it is evaluated economically and technically. The present study uses a novel optimum methodology for designing a combined solar/battery/diesel system in Yarkant, Xinjiang Uyghur Autonomous Region of China. In the desired system, the green energy combined system is designed to reduce the use of diesel generators. The diesel generator has been used in the photovoltaic, diesel, and battery to support green energy resources and batteries, as well as function as a backup generator for critical times whenever the production of green energy resources is low or the load demand is high. The amount of CO2 emitted, the probability of load shortage and the system cost on yearly basis are the major goals in the process of optimization. Here, the single‐objective problem is created by using the ε‐constraint technique to combine the many objectives. An improved Henry gas solubility optimizer handles the problem of optimization. To demonstrate the superiority of the strategy, a comparison is conducted between the simulation outcomes of the offered system, HOMER, and particle swarm optimizer ‐based optimum systems from the literature. The sensitivity of each parameter is also examined using sensitivity analysis.
Theoretical connection from the dielectric constant of films to the capacitance of capacitors under high temperature
Authors: Zhang Yongxin , Feng Qikun , Zhong Shaolong , Pei Jiayao , Chen Fangyi , Huang Lei , Yang Zhe , Dang Zhimin
Published: February 2023

In the process of coping with energy and environmental protection issues, technologies such as energy materials, energy devices, and energy systems have made great progress. With excellent performance, film capacitors play an increasingly important role in energy‐related fields. With the increase of application scenarios and the continuous development of film material technology, it is urgent to establish a better theoretical connection from films to capacitors. First, the main components of the capacitor including the film and the positional relationships among them are given. Then, from the two perspectives of indirect calculation according to the volume and the direct calculation according to the winding process, the equation between the dielectric constant of films and the corresponding capacitance of capacitors is established. Further, the measurement data and error analysis results of the built test platform prove the accuracy and great potential of the proposed calculation methods. In addition, error sources, including film thickness uniformity, are listed. Finally, the challenges faced by the proposed calculation methods and the paths that can be referenced for future research are summarised and discussed.
Retracted: Software solution for text summarisation using machine learning based Bidirectional Encoder Representations from Transformers algorithm
Authors: Al Abdulwahid Abdulwahid
Published: February 2023

Retraction: [Abdulwahid Al Abdulwahid, Software solution for text summarisation using machine learning based Bidirectional Encoder Representations from Transformers algorithm, IET Software 2023 (https://doi.org/10.1049/sfw2.12098)].

The above article from IET Software, published online on 2 February 2023 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the Editor‐in‐Chief, Hana Chockler, the Institution of Engineering and Technology (the IET) and John Wiley and Sons Ltd. This article was published as part of a Guest Edited special issue. Following an investigation, the IET and the journal have determined that the article was not reviewed in line with the journal’s peer review standards and there is evidence that the peer review process of the special issue underwent systematic manipulation. Accordingly, we cannot vouch for the integrity or reliability of the content. As such we have taken the decision to retract the article. The authors have been informed of the decision to retract.
Tidally perturbed gravity-mode pulsations in a sample of close eclipsing binaries
Authors: Van Reeth T. , Johnston C. , Southworth J. , Fuller J. , Bowman D. M. , Poniatowski L. , Van Beeck J.
Published: February 2023

Context. Thanks to the high-precision photometry from space missions such as Kepler and TESS, tidal perturbations and tilting of pulsations have been detected in more than a dozen binary systems. However, only two of these were gravity-mode (g-mode) pulsators.

Aims. We aim to detect tidally perturbed g modes in additional binary systems and characterise them observationally.

Methods. We performed a custom data reduction of the available Kepler and TESS photometry of a well-studied, published sample of 35 binary systems with γ Doradus (γ Dor) pulsators. For each target, we modelled the binary signal using a sum of 100 sine waves with frequencies at orbital harmonics and measured significant pulsation frequencies in an iterative pre-whitening analysis of the residual light curve. Pulsations are labelled as tidally perturbed g modes if they are part of both period-spacing patterns and multiplets spaced by integer multiples of the orbital frequency. After visual inspection and confirmation, the properties of these targets and g modes were characterised.

Results. We detect tidally perturbed g-mode pulsations for five short-period binaries that are circularised and (almost) synchronously rotating: KIC 3228863, KIC 3341457, KIC 4947528, KIC 9108579, and KIC 12785282. Tidally perturbed g modes that occur within the same star and have the same mode identification (k, m), are found to have near-identical relative amplitude and phase modulations, which are within their respective 1 − σ uncertainties and also identical for the Kepler and TESS photometric passbands. By contrast, pulsations with different mode identifications (k, m) are found to exhibit different modulations. Moreover, the observed amplitude and phase modulations are correlated, indicating that the binary tides primarily distort the g-mode amplitudes on the stellar surface. The phase modulations are then primarily a geometric effect of the integration of the stellar flux over the visible stellar surface. All selected binaries also exhibit signal that resembles rotational modulation in the Fourier domain. In the case of KIC 3228863, this is caused by the presence of the known tertiary component, and for the other systems we hypothesise that it is caused by temperature variations on the stellar surface. Alternatively, the signal can be made up of overstable convective modes in the stellar core or may belong to the non-pulsating companion.

Conclusions. While g-mode pulsation periods are known to be a direct probe of the deep interior stellar structure, the binary tides that cause the pulsation modulations are dominant in the outer stellar layers. Hence, in the future, tidally perturbed g modes may allow us to carry out core-to-surface asteroseismic modelling of tidally distorted stars.
Discovery of the C7N− anion in TMC-1 and IRC +10216
Authors: Cernicharo J. , Pardo J. R. , Cabezas C. , Agúndez M. , Tercero B. , Marcelino N. , Fuentetaja R. , Guélin M. , de Vicente P.
Published: February 2023

We report on the discovery of the C7N− anion towards the starless core TMC-1 and towards the carbon-rich evolved star IRC +10216. We used the data of the QUIJOTE (Q-band Ultrasensitive Inspection Journey to the Obscure TMC-1 Environment) line survey towards TMC-1 and found six lines in perfect harmonic frequency relation from J = 27  −  26 up to J = 32  −  31. The frequency of the lines can be reproduced with a rotational constant and a distortion constant of B = 582.68490 ± 0.00024 MHz and D = 4.01 ± 0.13 Hz, respectively. The standard deviation of the fit is 4 kHz. Towards IRC +10216, we identify 17 lines from J = 27  −  26 up to J = 43  −  42; their frequencies are also in harmonic relation, providing B = 582.6827 ± 0.00085 MHz and D = 3.31 ± 0.31 Hz. The nearly exact coincidence of the rotational and distortion constants in both sources points unambiguously to a common molecular carrier. Taking into account the chemical peculiarities of both sources, the carrier could be a radical or an anion. The radical can be discarded, as the observed lines belong to a singlet species. Hence, the most plausible carrier is an anion. High-level ab initio calculations indicate that C7N−, for which we compute a rotational constant of B = 582.0 MHz and a dipole moment of 7.5 D, is the carrier of the lines in both sources. We predict the neutral C7N to have a ground electronic state 2Π and a dipole moment of ∼1 D. Because of this low value of μ and to its much larger rotational partition function, its lines are expected to be well below the sensitivity of our data for both sources.
Sarcopenia Prevalence and Associated Factors in Male Patients with
Axial Spondyloarthritis
Authors: Shao Qin , Dai Min , Wei Lianggang
Published: February 2023

Background Sarcopenia is characterised by loss of muscle strength and
mass, leading to falls and adverse health outcomes. Our aim was to determine the
prevalence of sarcopenia in patients with axial spondyloarthritis (ax-SpA) and
to identify factors associated with sarcopenia in these patients.

Methods This cross-sectional study included 120 male patients with ax-SpA
and 100 healthy individuals matched for both sex and age. Sarcopenia was
assessed by muscle strength, muscle mass and physical performance using the
criteria determined by the Asian Working Group for Sarcopenia (AWGS). The
ankylosing spondylitis disease activity score (ASDAS), laboratory indicators and
bone mineral density were determined. Falls/fractures sustained over the
prior year were evaluated. The association between sarcopenia and clinical
characteristics was evaluated using logistic regression analyses.

Results According to the diagnostic criteria of AWGS 2019, the prevalence
of sarcopenia, severe sarcopenia and possible sarcopenia was 20.8%, 9.2
and 16.7% higher than in the healthy control population
(p<0.01). Factors associated with the prevalence of secondary sarcopenia
in ax-SpA were ASDAS, serum levels of prealbumin and 25-(OH)D as well as the
incidence of falls/fractures.

Conclusions Patients with ax-SpA have a high incidence of sarcopenia. The
development of sarcopenia was associated with high ASDAS, reduced levels of
prealbumin and 25-(OH)D as well as the incidence of falls/fractures.
Ligament Tension and Balance before and after Robotic-Assisted Total Knee Arthroplasty — Dynamic Changes with Increasing Applied Force
Authors: Sharma Abhinav K. , Plaskos Christopher , Shalhoub Sami , Lawrence Dylan , Vigdorchik Jonathan M. , Lawrence Jeffrey M.
Published: February 2023

The optimal force applied during ligament balancing in total knee arthroplasty (TKA) is not well understood. We quantified the effect of increasing distraction force on medial and lateral gaps throughout the range of knee motion, both prior to and after femoral resections in tibial-first gap-balancing TKA. Twenty-five consecutive knees in 21 patients underwent robotic-assisted TKA. The posterior cruciate ligament was resected, and the tibia was cut neutral to the mechanical axis. A digital ligament tensioning tool recorded gaps and applied equal mediolateral loads of 70 N (baseline), 90 N, and 110 N from 90 degrees to full extension. A gap-balancing algorithm planned the femoral implant position to achieve a balanced knee throughout flexion. After femoral resections, gap measurements were repeated under the same conditions. Paired t-tests identified gap differences between load levels, medial/lateral compartments, and flexion angle. Gaps increased from 0 to 20 degrees in flexion, then remain consistent through 90 degrees of flexion. Baseline medial gap was significantly smaller than lateral gap throughout flexion (p <0.05). Increasing load had a larger effect on the lateral versus medial gaps (p <0.05) and on flexion versus extension gaps. Increasing distraction force resulted in non-linear and asymmetric gap changes mediolaterally and from flexion to extension. Digital ligament tensioning devices can give better understanding of the relationship between joint distraction, ligament tension, and knee stiffness throughout the range of flexion. This can aid in informed surgical decision making and optimal soft tissue tensioning during TKA.
Top 50 Most-Cited Publications on Blepharoplasty Surgery Between 2015 and 2022: From a Current Altmetric Perspective of Research Impact
Authors: Evereklioglu Cem , Sener Hidayet , Horozoglu Fatih
Published: February 2023

Background Blepharoplasty is one of the most-performed esthetic operations, and social media platforms have become an influential tool for distributing scientific information. Because the internet has gained popularity among medical experts and surgeons to connect with the public, we aimed to evaluate the altmetric–bibliometric analysis of the top 50 most-cited articles on blepharoplasty surgery between 2015 and 2022 and assess correlations with various metrics.

Methods “Blepharoplasty” was searched using the WoS database, and the altmetric score was obtained. Co-authors, keywords, country of authors, and cited journal network map analysis were created using VOSviewer for the 485 publications retrieved. The articles' focus was examined quantitatively and the most prolific parameters were identified.

Results The most research was performed by the USA, the most productive institution was the “University of California System,” and the most prolific author was “Wonn CH.” The number of citations ranged from 37 to 9, and altmetric attention scores ranged from 54 to 0. The most articles and citations peaked in 2021. Altmetric and Twitter scores were moderately correlated with journal metrics but there were no correlations with citation counts.

Conclusion The first comprehensive altmetric analysis on blepharoplasty surgery offers new guidelines for upcoming articles by demonstrating the recent investigation trends, prolific parameters, and zones with potential for the public's attention and education, providing valuable data regarding the distribution of scientific knowledge in social media platforms and to the general public. A social network may be used to increase the visibility of scientific articles apart from creating brands and markets.
Interstitial Ectopic Pregnancy with Enhanced Myometrial Vascularity: A Rare Case Successfully Treated with Uterine Artery Embolization
Authors: Khurana Navpreet Kaur , Gangwani Gaurav , Thiyagarajan Kamalapriya , Chaurasia Aditi , Thakre Akanksha
Published: February 2023

Enhanced myometrial vascularity (EMV) is a rare disorder associated with various obstetrical and gynecological pathologies. We describe a unique case of interstitial ectopic pregnancy associated with EMV successfully managed with bilateral uterine artery embolization.
Drug–Drug Interactions in the Treatment of Cancer-Associated Venous Thromboembolism with Direct Oral Anticoagulants
Authors: Hellfritzsch Maja , Henriksen Jakob Nørgaard , Holt Marianne Ingerslev , Grove Erik Lerkevang
Published: February 2023

Venous thromboembolism (VTE) is a frequent complication of cancer, and management of cancer-associated thrombosis (CAT) is challenging due to increased risks of bleeding and recurrent VTE. Recent trials have shown an acceptable efficacy and safety of direct oral anticoagulants (DOACs) in the treatment of CAT compared to low-molecular weight heparin. Although DOACs provide an effective and convenient treatment option in CAT, the need to assess the risk of drug–drug interactions (DDI) with antineoplastic therapies poses a barrier to their use in clinical practice. With the aim of supporting the assessment of CAT patients for treatment with DOAC, this review provides a comprehensive overview of the compatibility of antineoplastic therapies with the individual DOACs (apixaban, dabigatran, edoxaban, and rivaroxaban). Using several data sources, we characterized 100 widely used antineoplastic agents with regard to their effect on p-glycoprotein and cytochrome P450, both important in the transport and elimination of DOACs. This enabled us to evaluate 400 “DOAC-antineoplastic agent”-pairs regarding their likelihood to interact (unlikely, potential, or likely), ultimately leading to clinical recommendations on the appropriateness of concomitant use for each pair. A potential or likely DDI was identified for 12% of the evaluated pairs. For nearly all antineoplastic agents, at least one DOAC was considered compatible.