bluuebunny/crossref_metadata_2025 huggingface dataset:
Gastric Cancer Screening in First-Degree Relatives: A Pilot Study in a Diverse Integrated Healthcare System
Authors: Dong Elizabeth Y. , Giap Andrew Q. , Lustigova Eva , Wu Bechien U.
Published: September 2022

INTRODUCTION

Family history of gastric cancer has been shown as an independent risk factor of gastric cancer development and is associated with increased risk of progression to gastric cancer among patients with gastric intestinal metaplasia (GIM).

METHODS

Between 2017 and 2020, we conducted a prospective pilot screening program of patients with a confirmed first-degree relative with gastric cancer to evaluate the feasibility of screening and prevalence of precursor lesions (e.g., GIM or dysplasia) on biopsy.

RESULTS

A total of 61 patients completed screening by upper endoscopy with a mapping biopsy protocol: 27 (44%) were found to have GIM and 4 (7%) were found with low-grade dysplasia.

DISCUSSION

Our pilot screening program identified a high prevalence of precursor lesions for gastric cancer among asymptomatic patients with a first-degree relative with gastric cancer. Careful endoscopic inspection and standardized biopsy protocols may aid in prompt identification of these precursor lesions in those at risk of gastric cancer.
Determinants of Islamic Equity Funds Performance: Case Study of Indonesia
Authors: Rahman Fadel , Qoyum Abdul
Published: September 2022

The performance of Islamic mutual funds is significant either for investors or policy-makers. Many factors affect the performance of Islamic mutual funds, such as internal factors, external factors (macroeconomics), and market index. This study aims to analyze the impact of the past return of Islamic mutual fund, BI rate, and the Jakarta Islamic Index (JII) on the performance of Islamic equity mutual funds. By employing panel data regression analysis, this study documented some interesting findings. The statistical testing revealed that BI rate, which is used as an indicator for external factors and JII (as Market factors), have a positive impact on the performance of Islamic equity mutual funds. In contrast, the past return does not affect the performance of Islamic equity funds. This study suggests that the investor must consider internal, and external factor in the investment activities.
Zakah Contribution for Community Economic Development with Analytical Networking Process Method
Authors: Hasbi M Zidny Nafi' , Widayanti Ipuk
Published: September 2022

The purpose of this study is to describe theoretically and applied zakat as an Islamic financial instrument that has one function to alleviate poverty. The function of zakat is in line with the goal of sustainable community economic development which is a form of global commitment in spurring economic growth for the better. This type of research is mixed methods using the Analytical Process Networking approach. The analysis technique of this research used purposive sampling. Objects in the study include zakat management organizations, academics, government, and practitioners. The findings of this study are that the priority of implementing zakat distribution in supporting sustainable community economic development is the social aspect with a rater agreement W=0.36444. Four strategies can achieve sustainable community economic development, namely: 1) Improving the quality and quantity of concern for community social institutions and stakeholders; 2) Improve disaster risk reduction comprehensively and efficiently; 3) Improving the quality of fair law enforcement 4) Increasing job opportunities and concern for community MSMEs.
Techniken der Täuschung?
Authors: Rein Katharina
Published: September 2022

Katharina Reins preisgekrönte kulturwissenschaftliche Dissertation widmet sich der Bühnenzauberkunst in ihrem »Goldenen Zeitalter« (ca. 1860–1900), das von wissenschaftlicher und technischer Innovation ebenso geprägt war wie von einer florierenden Medienkultur, den Umbrüchen der Industrialisierung oder den Erfahrungen von Globalisierung und Kolonialismus. Moderne Bühnenzauberei beansprucht keine übernatürliche Wirkung, vielmehr präsentiert sie technisch erzeugte Illusionen, deren Funktionsweisen sie allerdings verbirgt. Sie stellt damit eine spezifische Form des Mediengebrauchs dar, die mediale Effekte exzessiv ausstellt, während sie das dahinterstehende technische Geschehen zum Verschwinden bringt. Die Analyse von vier paradigmatischen Großillusionen (»Pepper’s Ghost«, »Vanishing-Lady«-, Levitations- und Telepathie-Illusion) eröffnet nicht nur schlaglichtartige Einblicke in die bislang weitgehend ungeschriebene Zaubergeschichte des späten 19. Jahrhunderts. Sie geben zugleich die Sicht frei auf einschneidende kulturelle Veränderungen und Innovationen, die in diese moderne, hoch technisierte Form von Magie Eingang fanden.
Editorial
Authors: Skřejpková Petra
Published: September 2022

Editorial
Od sestry k nuzné vdově. Změny postavení manželky v římském dědickém právu
Authors: Dostalík Petr
Published: September 2022

This paper deals with the position of wife in the Roman law of succession from the earliest period (as far as the Law of the Twelve Tables) to the changes of the law of intestate succession made by emperor Justinian. This paper follows changes in the position of a wife in case of the death of the husband. This position was determined by type of marriage (strict or free form of the marriage) and was deeply influenced by the reform of the law of succession made by praetor. Even in the praetorian law, the position of the wife and her possibility to obtain some substantial part of the deceased husband’s property was limited and nothing had changed also after the codification of Corpus Iuris Civilis. In order to defend the natural (and justified) needs of widow, emperor Justinian introduced a special provision for so-called needy widow (and temporarily even for the needy widower). The paper examines very closely those provisions and states that the protection of the needy widow can be marked as one the basic values of the Roman law of succession.
Meziválečné osnovy OZ „pohledem žen“
Authors: Salák Pavel
Published: September 2022

The text does not intend to cover the legal position of women in the interwar drafts of a civil code in a complex manner, instead, it focuses on three different family law issues which were chosen to display how the views and demands of women were (or were not) reflected. As the authors of the recodification were exclusively men, the „women’s point of view“ is merely men’s vision of what the needs of women were. The three different issues are not directly linked, however, they show different approaches of the authors of the recodification.
O uhorských pozemkových knihách a ich spravovaní
Authors: Jakubáč Róbert
Published: September 2022

The aim of this paper is to present the legal regulation and administration of land registers in Hungary since the middle of the 19th century, as well as the reasons for the establishment of the so-called public books. Special attention is paid to the legal regulation of entries in the land registers. In conclusion, the author states that land registers are still important, and that the application practice must deal with entries in the land registers.
Csukás, A. Právní řád Českobratrské církve evangelické v historických souvislostech
Authors: Beránek Jan
Published: September 2022

Book review on Csukás, A. Právní řád Českobratrské církve evangelické v historických souvislostech. Jihlava: Mlýn, 2022, 343 s.
Horák, O. – Razim, J. Dějiny kodifikace soukromého práva v českých zemích
Authors: Kabát Jan
Published: September 2022

Book review on Horák, O. – Razim, J. Dějiny kodifikace soukromého práva v českých zemích. Praha: Leges, 2020, 140 s.
Laclavíková, M. – Záteková-Válková, V. Rozvod manželstva v spoločnosti budujúcej socializmus (Československá rozvodová súdna prax v 50. a 60. rokoch 20. storočia)
Authors: Švecová Adriana
Published: September 2022

Book review on Laclavíková, M. – Záteková-Válková, V. Rozvod manželstva v spoločnosti budujúcej socializmus (Československá rozvodová súdna prax v 50. a 60. rokoch 20. storočia). Praha: Leges, 2020, 164 s.
Vyšný, Peter. El derecho en Tenochtitlan. Aspectos jurídicos del orden social de una ciudad-estado prehispánica [= Právo v Tenochtitlane. Právne aspekty spoločenského poriadku jedného predhispánskeho mestského štátu]
Authors: Puchovský Ján
Published: September 2022

Book review on Vyšný, Peter. El derecho en Tenochtitlan. Aspectos jurídicos del orden social de una ciudad-estado prehispánica [= Právo v Tenochtitlane. Právne aspekty spoločenského poriadku jedného predhispánskeho mestského štátu]. Praha: Leges, 2019, 304 s.
Mechanical and morphological characterization of sisal/kenaf/pineapple mat reinforced hybrid composites
Authors: Felix Sahayaraj A. , Jenish I. , Tamilselvan M. , Muthukrishnan M. , Kumar B. Ashok
Published: September 2022

The objective of this research is to produce and analyze natural fiber-based composites (sisal/polyester, kenaf/polyester, pineapple/polyester) and their hybrid composites (sisal/kenaf/polyester, kenaf/pineapple/polyester, and sisal/kenaf/pineapple/polyester) made by compression molding. These composites were characterized mechanically using hardness (shore D), tensile, flexural, and impact (Charpy) tests. Fiber matrix bonding was analyzed using Scanning Electron Microscopy (SEM). Among all the fiber-based samples (sisal/polyester, kenaf/polyester, and pineapple/polyester), sisal/polyester shows a high hardness value of 93.24 Sd, a tensile strength of 43.00 MPa, and an impact strength around 7.42 kJ/m2, while pineapple/polyester produces a better flexural strength of 83.21 MPa. Hybrid composites showed improved mechanical performance. The mechanical characteristics of the sisal/kenaf/pineapple/polyester hybrid composite were 56.16 MPa, 1.71 GPa, and 9.34 kJ/m2. The highest flexural strength of the Sisal/kenaf/polyester multi-layered samples was observed as 83.24 MPa.
Simple preparation and investigation of magnetic nanocomposites: Electrodeposition of polymeric aniline-barium ferrite and aniline-strontium ferrite thin films
Authors: Sharifi Farzaneh , Hedayati Kambiz , Ghanbari Davood
Published: September 2022

In this work, new polymeric aniline-barium ferrite and aniline-strontium ferrite thin layers were synthesized. In the first step, hexaferrites nano-additives were prepared by applying ultra-sound and microwave irradiation. Then, hexaferrites were added to aniline electrolyte solution separately. The electrodeposition of aniline as a polymeric matrix and hexaferrite as nano-additives was performed in an electrochemical cell in the presence of various acids. Scanning electron microscopy images were applied for morphology investigation and measuring average particle size. Energy dispersive X-ray spectroscopy was applied for elemental detection and analysis, as well as presence confirmation of nanoparticles. Atomic force microscopy was applied for surface roughness analysis of thin films. Magnetic property of the nanoparticles and polymeric nanocomposites was checked and measured by vibrating sample magnetometer. The crystallinity, crystallite size, and phase of samples were confirmed by X-ray diffraction pattern analysis.
The crystal structure of 3,7-dihydroxy-9-methoxy-4a-methyl-4aH-benzo[c] chromene-2,6-dione —dichloromethane (1/1), C16H14Cl2O6
Authors: Liu Juan , Chen Sai , Wang Meng , Yuan Wei-Hua , Li Honglei
Published: September 2022

C16H14Cl2O6, monoclinic, P21/c (no. 14), a = 8.9847(19) Å, b = 18.284(4) Å, c = 11.107(3) Å, β = 115.942(2)°, V = 1640.7(7) Å3, Z = 4, R
gt(F) = 0.0473, wR
ref(F
2) = 0.1352, T = 273 K.
Chemical composition and anticholinesterase activity of Lepisanthes rubiginosa (Roxb.) Leenh. essential oil
Authors: Salleh Wan Mohd Nuzul Hakimi Wan , Ghani Nurunajah Ab , Abdel-Aal Abu-Baker M.
Published: September 2022

Essential oils obtained from medicinal plants show high therapeutic potential against several types of pathologies, including Alzheimer’s disease. The purpose of this work was to study the chemical composition and anticholinesterase inhibitory activity of the essential oil obtained from Lepisanthes rubiginosa leaves collected from Malaysia. Twenty-four components were identified using gas chromatography-flame ionization detection (GC-FID) and gas chromatography/mass spectrometry (GC-MS), which represent 99.5% of the essential oil. The identified major components include α-cadinol (40.0%), safrole (12.6%), α-amorphene (9.5%), (E)-isosafrole (5.0%), δ-cadinene (4.2%), and t-muurolol (4.1%). Anticholinesterase activity was assessed using Ellman method, and the essential oil demonstrated a moderate inhibitory activity against acetylcholinesterase (I%: 75.2%) and butyrylcholinesterase (I%: 70.2%) at conconcetration of 1000 μg/mL. The current study is the first to report chemical composition and anticholinesterase activity of the essential oil obtained from L. rubiginosa, which may have implications on the characterization, pharmaceutical, and therapeutic applications of Lepisanthes genus essential oils.
The Effect of the Real
Authors: Lebow Alisa
Published: September 2022

On the occasion of his recent essay film Mariner of the Mountains, the queer Brazilian director Karim Aïnouz reflected upon his career in a wide-ranging conversation with FQ contributing editor Alisa Lebow. Spanning themes from Aïnouz’s insider/outsider status as a gay Brazilian with a foreign name to his reputation as a consummate director of “women’s films,” the interview presents a comprehensive overview of Aïnouz’s oeuvre: from his first feature film Madame Satã to his first English-language film Firebrand, about the life of Henry VIII’s last wife Catherine Parr, currently in production.
Thessaloniki
Authors: Grgić Ana , Lagarias Antonis
Published: September 2022

Ana Grgić and Antonis Lagarias report from the Thessaloniki Documentary Festival, which celebrated its 24th year with a return to in-person programming following the pandemic. Reflecting a programmatic interest in cinematic themes relating to the future of a humanity facing ecological and techno-existential threats, the festival’s focus was “postreality,” a popular term for indicating the sensory world’s mediation through images and virtual universes. Outside of this special focus on documentaries that challenge conceptions of the “real” world, films employed a range of archival materials to explore issues of individual and collective memory. The festival’s retrospective focused on the Latvian director Laila Pakalniņa, whose central preoccupation is observing and documenting a subjective view of reality.
A critical evaluation of the EU-virtual consultation platform (CPMS) within the European Reference Network on Rare Endocrine Conditions
Authors: White E K , Wagner I V , van Beuzekom C , Iotova V , Ahmed S F , Hiort O , Pereira A M
Published: September 2022

In 2017, the European Commission installed 24 European Reference Networks (ERNs) for different categories of rare and complex conditions to facilitate cross-border health care via virtual case consultations in a secure Clinical Patient Management System (CPMS). The ERN for rare endocrine conditions (Endo-ERN) previously reviewed the CPMS, in which they detailed the difficulties physicians encountered with the system and proposed solutions to these that should enable the system to be used to a greater extent. This paper will further the endeavor of the first by performing a critical evaluation of the CPMS, assessing how these suggested improvements have been implemented, and if these have affected the usage of the system. The evaluation involves an assessment of CPMS usage statistics since its conception that takes into consideration the technical updates and the external factors that may have affected these, including data from a review survey following a training workshop for our new healthcare providers (HCPs) added in January 2022. It appears that the improvements made to the system since the first review, in particular the implementation of the Operational Helpdesk, have had a positive effect in increasing CPMS membership; however, the regular usage of the system continues to fluctuate. Several suggestions are made on how to further facilitate the use of CPMS by our members both individually and network-wide, by integrating CPMS activities with other network initiatives and further integrating these into national health care systems as well as looking for ways to measure patient satisfaction from the CPMS discussions outcomes.
Effects of additives on absorbable organic halide reduction in elemental chlorine-free bleaching of bagasse kraft pulp
Authors: Yao Shuangquan , Gao Cong , Zhu Huixia , Zhang Yixia , Wang Shuangfei , Qin Chengrong
Published: September 2022

In order to further reduce absorbable organic halide (AOX) formation in the bleaching effluent, NH2SO3H and DMSO were added during the elemental chlorine-free (ECF) bleaching (D0EpD1) of bagasse kraft pulp. In the D0 stage, AOX formation decreased by 10% with 0.1% NH2SO3H, and a reduction of 11.2% with 1.0% DMSO, respectively. Ultraviolet (UV) spectra, Fourier transform infrared spectroscopy (FTIR), and gas chromatography-mass spectroscopy (GC-MS) were adopted in characterizing changes of lignin degradation and the main functional groups of bleached pulp. The UV spectrum showed that the quantity of polyphenols decreased after adding the additives. The FTIR spectrum showed that both the content of phenolic-type lignin and the degradation degree of lilac-type lignin decreased after adding NH2SO3H. If was found that DMSO was beneficial in retaining C-O-C and C=O structures in cellulose and hemicellulose, while NH2SO3H decreased the content of β-glycosidic bonds and C-O-C structures in cellulose and hemicellulose. The composition of lignin degradation products in the bleaching effluent was analyzed by GC-MS. The contents of chlorobenzene and chlorophenol decreased notably when additives were added. Compared with DMSO, NH2SO3H exhibited poor inhibition on the formation of some phenols.
Effect of cold plasma surface pre-treatment of wheat straw particles on straw board properties
Authors: Hýsek Štěpán , Podlena Milan , Böhm Martin , Bartsch Henry , Wenderdel Christoph
Published: September 2022

Effects of the plasma treatment were evaluated for particles from winter wheat stalks relative to the properties of particleboards manufactured from such treated particles. Using urea-formaldehyde adhesive, boards with a nominal density of 540 kg/m3 and a thickness of 6 mm were manufactured. Two degrees of plasma treatment were selected: cold plasma applied at atmospheric pressure by jet system, with a generator output voltage of 26.9 V and a current of 6.9 A; and in the second treatment, a maximum voltage of 28.6 V was used with a current of 8.7 A. The physical properties (equilibrium moisture content and thickness swelling depending on relative humidity) and mechanical properties (bending strength and tensile strength perpendicular to the plane of the board) were determined. The results showed that the plasma pre-treatment of particles had a statistically significant effect on the resulting composite properties. The mechanical properties of the boards increased with both plasma treatments, but the physical properties changed negatively. Boards manufactured from particles treated with a higher degree of plasma treatment resulted in significantly higher equilibrium moisture contents and thickness swelling than the reference boards.
Improvement to the solubility and reactivity of purified bamboo fibers using a combined chemi-mechanical process
Authors: Li Man , Fang Guigan , Cai Zhaosheng , Zhou Jing , Fan Hongyu
Published: September 2022

Bamboo fibers exhibit poor solubility and reactivity because of the aggregational structure of cellulose macro-molecules in fiber cell walls. It has been shown that more free hydroxyl groups on cellulose molecules can be exposed via fibrillation of the fiber walls during a PFI beating process. The changes in fiber characteristics, such as the fibrillation degree, water retention value (WRV), and crystallinity, were analyzed. The results showed that the fiber fibrillation increased from 0.781% to 1.072%, and the WRV increased from 112.8% to 213.6% during the beating process, indicating that a fibrillation effect was present in the bamboo fiber walls that corresponded to an incremental change in the degree of mechanical pretreatment. The saturated solubility value of the treated fibers in an alkali/urea solvent system at low temperature increased from 0.22 wt.% to 2.69 wt.% with an incremental change in the degree of mechanical pretreatment. After high-revolution PFI beating, the cellulose crystallinity index of the samples decreased from 66.4% to 50.0%, but the intrinsic viscosity changed only slightly. The oxidation degree of the cellulose in the treated samples increased from 0.85 mol/AGU to 1.03 mol/AGU, which suggested that the reagent accessibility and chemical reaction performance of the bamboo fibers were both improved.
Lignin content of agro-forestry biomass negatively affects the resultant biochar pH
Authors: Huang Yuwei , Li Fengcheng , Meng Jun , Chen Wenfu
Published: September 2022

The biomass type is one of the most important factors that affects biochar properties, but the relationship between the major constituents of different biomasses and the properties of the derived biochars, especially the pH, is still unclear. In this study, the cellulose, hemicellulose, lignin, and ash contents of 30 representative agro-forestry biomasses and the pH, surface acid functional groups, and carbonates of 150 resultant biochars prepared with different heat treatment temperatures (HTTs) were examined. The results showed that the lignin content of the biomass had a strong negative correlation with the biochar pH (r = −0.428, P < 0.01). When the HTT was 300 °C, a high lignin content in the biomass was found to have increased the acid functional groups in the biochar, which resulted in a relatively low pH. When the HTT was greater than or equal to 400 °C, the high lignin content in the biomass negatively correlated to the carbonates, which led to a low biochar pH. It was concluded that the lignin content of agro-forestry biomass affects the biochar pH negatively, and the acid functional groups and carbonates have different effects at different HTTs.
Determination of Surface Roughness Based on the Sanding Parameters of Oriental Beech Wood
Authors: İlçe Abdullah Cemil
Published: September 2022

This study demonstrated the strength of a theoretical model founded on the Box-Behnken experimental design method to determine the surface roughness (Ra parameter) of solid Oriental beech (Fagus orientalis Lipsky) wood. The working parameters (sanding belt grit size of 60 to 100, feeding speed of 4 m/min to 10 m/min, and sanding cutting depth of 0.1 mm to 0.3 mm) of a wide belt sanding machine were determined. The Ra of the samples was experimentally described so that the experimental results were also remodeled with the Box-Behnken method to find the optimum parameters for the lowest Ra. An adjusted correlation factor of 93.6% for the Ra confirmed the compatibility between the experimental and theoretical findings. The high correlation (strength) allowed for a more detailed discussion of the effect of the working parameters on the Ra. The theoretical approach showed that the grit size factor had the largest effect on the Ra compared with the other factors. The optimum parameters were found to be a grit size of 100, feed speed of 4 m/min, and sanding depth of 0.1 mm for a minimum Ra for Oriental beech wood. The experimental data supported these parameters.
Diabetic retinopathy diagnosis using image processing methods
Authors: Bakhshi Ali , Hajizadeh Kobra , Tanhayi Mohammad Reza , Jamshidi Reza
Published: September 2022

Diabetes mellitus is common disease nowadays which could cause blindness. Earlier detection of diabetes signs from retina fundus images could help predicting and preventing the damages. Image processing methods could process the matrix data of pictures as blood vessel segmentation and exudate detection. In this research, the CLAHE algorithm with morphological transformations are used to blood vessel segmentation and determination of the Hessian matrix of images are utilized to detect the exudate blobs
Ichthyofauna species diversity in multipurpose water bodies of the forest-steppe zone of Ukraine by river basins
Authors:   Na­tio­nal University of Life and Environmental Sciences of Ukraine, Kyiv, Khalturin M. , Klymovets’kyi A. ,   Na­tional University of Life and Environmental Sciences of Ukraine, Kyiv, Shevchenko P. ,   National University of Life and Environmental Sciences of Ukraine, Kyiv
Published: September 2022

Purpose. To investigate fish fauna of multipurpose water bodies in the Forest-Steppe Zone of Ukraine in the basin of two rivers: South Bug (South Bug, Gnylyi Tikich), Dnipro (Dnipro, Ros, Desna rivers). To select equal water bodies based on their areas and degree of location relative to their main basin and compare these water bodies based on their similarity and typicality. Methodology. The collection of materials was carried out during 2010-2017 in multipurpose water bodies located in the forest-steppe zone of Ukraine in the basins of large rivers such as the Dnipro and the Southern Bug. Samples were taken along the Dnieper immediately below the basin of the Ros River, which flows into the Kremenchuk Reservoir on the Dnieper. As far as the Southern Bug, the samplings were not conducted below the Hlybochok HPP. Control catches were carried out with gill nets with mesh sizes of 40-80 mm, as well as with a 25-m-long fry beach seine with a mesh of 10 mm. Collection and processing of ichthyological materials was carried out according to generally accepted methods. When determining the impact of recreational and sports fishing, direct counting was used, which was carried out by means of route visits to the places of accumulation of recreational fishermen and their surveys. The Serenson’s similarity index was used to analyze the degree of similarity of ichthyofauna groups of water bodies: S = 2 С/А+В, where А — number of species in the first community, В — number of species in the second community, С — number of species common to both communities The typicality of ichthyofauna cimmunities by species richness was determined by the formula proposed by Shannon-Weaver: Rs=ni/N, where ni — number of species for the studied area, N — total number of species for the region. MS Excel was used for processing the obtained results. Findings. The fish fauna of the studied water bodies of the forest-steppe zone during the study period was not large enough in terms of species. A zonal distribution of fish fauna was observed in different rivers’ reaches, with a gradual decrease of native species towards invaders and acclimatizers, due to their constant stocking of multipurpose water bodies. This was especially observed on the Gnylyi Tikich River. Practical value. The similarity and typicality indices of river ecosystems were the most similar in this case of the Ros and Desna rivers, it is completely natural and highly probable. Therefore, it is necessary to continue researching rivers, and to carry out measures to reacclimatize native species typical for this region, especially commercially valuable species. Key words: native species, invaders, acclimatizeers, Ros River, Gnylyi Tikich River, Desna River, similarity index.
Hydrochemical parameters in ponds of the State Enterprise «Experimental Fish Farm ‘‘Nyvka’’» of the Institute of Fisheries of the National Academy of Agrarian Sciences of Ukraine in the context of requirements for the aquatic environment for largemouth bass (Micropterus salmoides Lacepede, 1802)
Authors:   State Agency of Melioration and Fisheries of Ukraine, Kyiv, Gushchyn V.
Published: September 2022

Purpose. Largemouth bass (Micropterus salmoides), a fish native to freshwaters of North America, is adapted within its natural and introduced ranges to freshwater biotopes with temperate climatic conditions. Considering the fact that biotopes in temperate climatic conditions are usually characterized by a significant diversity of physicochemical parameters, it can be concluded that largemouth bass is adapted to a broad range of hydrochemical parameters of the aquatic environment. However, such an adaptive range has its own limiting values, and a long stay of fish in an aquatic environment, the hydrochemical parameters of which approach the upper or lower limit of the adaptive range, can make negatively affect their growth, development, activity, ability to withstand stress factors, as well as inhibit reproductive function. This work examines favorable and unfavorable parameters of the aquatic environment, that have the greatest impact in the process of growing of largemouth bass, as well as an analysis of hydrochemical parameters of ponds of the State Enterprise «Experimental Fish Farm «Nyvka»» of the Institute of Fisheries of the National Academy of Agrarian Sciences of Ukraine for the possibility of growing this species. Findings. This paper contains brief information about main hydrochemical parameters that can have a negative impact on largemouth bass within natural or aquaculture water bodies as well as a comparison of their values ​​with some parameters of the aquatic environment of ponds of the State enterprise «Experimental Fish Farm «Nyvka» of the Institute of Fisheries of the National Academy of Agrarian Sciences of Ukraine obtained during hydrochemical studies in 2018-2019. Practical value. The information from this review can be used in further cultivation of largemouth bass in full-system warm-water pond fish farms with water supply from rivers with the drainage basin located in areas with a high level of urbanization. Keywords: largemouth bass, Micropterus salmoides, hydrochemical parameters, pond farming, aquaculture, adaptation, mineralization, pH, general hardness.
Time kill-assays of antibiotic combinations for multidrug resistant clinical isolates of OXA-48 carbapenemase producing Klebsiella pneumoniae
Authors: Erdem Fatma , Díez-Aguilar María , Oksuz Lutfiye , Kayacan Cigdem , Abulaila Ayham , Oncul Oral , Morosini María Isabel , Cantón Rafael , Aktas Zerrin
Published: September 2022

Treatment of infections caused by OXA-48 carbapenemase producing multidrug-resistant isolates often necessitates combination therapy. In vitro effect of different antibiotic combinations against multidrug-resistant (MDR) Klebsiella pneumoniae isolates were evaluated in this study.

Meropenem-tobramycin (MER+TOB), meropenem-ciprofloxacin (MER+CIP), colistin-meropenem (COL+MER), colistin-ciprofloxacin (COL+CIP) and colistin-tobramycin (COL+TOB) combinations were tested by time kill-assays. Each antibiotic alone and in combination at their Cmax values were tested against 4 clinical K. pneumoniae isolates at 1, 2, 4, 6, 8, 12 and 24 h. Effect of colistin and its associations were also assessed at 30 min. Bactericidal activity was defined as ≥3log10 CFU mL−1 decrease compared with initial inoculum. Synergy was defined as ≥2log10CFU mL−1 decrease by the combination compared with the most active single agent. Presence of bla
OXA-48, bla
NDM, bla
VIM, bla
IMP, bla
KPC and bla
CTX-M-1 genes was screened by PCR using specific primers.

The bla
OXA-48 gene was identified together with bla
CTXM-1 group gene in all isolates. COL+MER demonstrated to be synergistic and bactericidal. MER+TOB showed synergistic and bactericidal effect on two strains although, regrowth was seen on other two strains at 24 h. MER+CIP exhibited indifferent effect on the strains.

Combination therapy could be a potential alternative to treat MDR K. pneumoniae infections. This combination might prevent resistance development and secondary effects of colistin monotherapy. MER+TOB and MER+CIP might have an isolate-dependent effect, that may not always result in synergism.
Another failure of the latent disease model? The case of compulsive sexual behavior disorder •
Authors: Borgogna Nicholas C. , Aita Stephen L.
Published: September 2022

Recent debates have evolved regarding the classification/conceptualization of compulsive sexual behavior disorder (CSBD). Conclusions regarding an agreed upon CSBD model are hindered by reliance on the latent disease model. Competing biological-based frameworks are moving forward to replace latent disease classification more broadly but have been met with limited success. We suggest that CSBD researchers move towards developing dimensional, transtheoretical, process-based models. We further suggest additional research, particularly mixed methods and longitudinal studies. Finally, we request that federal funding bodies take a more active role in supporting CSBD research.
Organic crystal structure prediction and its application to materials design
Authors: Zhu Qiang , Hattori Shinnosuke
Published: September 2022

In recent years, substantial progress has been made in the modeling of organic solids. Computer simulation has been increasingly shaping the area of new organic materials by design. It is possible to discover new organic crystals by computational structure prediction, based on the combination of powerful exploratory algorithms and accurate energy modeling. In this review, we begin with several key early concepts in describing crystal packing, and then introduce the recent state-of-the-art computational techniques for organic crystal structure prediction. Perspectives on the remaining technical challenges, functional materials screening and software development are also discussed in the end. It is reasonable to expect that, in the near future, accurate predictive computational modeling can be accomplished within a time frame that is appreciably shorter than that needed for the laboratory synthesis and characterization.

Graphical abstract
IS THE ANATOMICAL SEQUENCE OF GASTRIC AND BILIARY ANASTOMOSIS IN THE PANCREATODUODENECTOMY RECONSTRUCTION THE CAUSE OF AN INCREASE IN THE INCIDENCE OF CHOLANGITIS? A TECHNICAL VARIANT PRESENTATION AND INITIAL RESULTS
Authors: NARI Gustavo Adrian , LOPEZ Alesio , LAYUN Jose Luis , MARIOT Daniela , LOPEZ Flavia , DE-ELIAS Maria Eugenia
Published: September 2022

ABSTRACT - BACKGROUND: Several methods have been proposed for the reconstruction of digestive transit after pancreatoduodenectomy. Biliary anastomosis positioned before gastric anastomosis helps reduce postoperative reflux and cholangitis. AIMS: The objective of this study was to present the anatomical sequence of gastric and biliary continuity after pancreatoduodenectomy in patients with pancreatic tumor and to evaluate the short- and long-term results in an initial series of cases. METHODS: Two techniques were used: one with Roux-en-Y reconstruction and pancreaticojejunostomy and the other with a single jejunal loop and pancreatogastroanastomosis. In both the cases, the gastric anastomosis was placed performed before the biliary one. An analysis of demographic data, Wirsung’s duct and common bile duct dilatation, the use of percutaneous drainage, and postoperative complications was carried out. RESULTS: A total of seven patients (four men and three women), with a mean age of 62 years, underwent surgery. All cases had Wirsung’s duct and common bile duct dilatation. A percutaneous external biliary drainage was performed in four patients. There were three postoperative complications: one related to delayed gastric emptying and two related to wound infections. During a median follow-up of 12 months, no episode of cholangitis was recorded. CONCLUSIONS: Elevated percentages of cholangitis are reported in different reconstructions after pancreatoduodenectomy, and it is difficult to conclude reflux as the main etiology. The proposed gastric and biliary reconstructions show conforming results, facilitating posterior endoscopic access. Late follow-up and large number of cases may help assess whether the etiology of postoperative cholangitis is reflux or other factors unrelated to the order of the anastomoses.
A comparison of the economic results obtained by Holstein steer calves with different feedlot arrival body weights
Authors: Barreras-Serrano Alberto , Flores-Garivay Rodrigo , Sanchez Eduardo , Zinn Richard
Published: September 2022

ABSTRACT: The study compared the economic results between five groups of Holstein steers with different arrival body weights (ABW) but similar ages in the feedlot. The average ABW were 105, 112, 117, 123 and 129 kg (30, 90, 87, 60, and 30 calves, respectively) with an age of 113 ± 1d. The calves were randomly distributed using an unbalanced design. The calves were weighed upon arrival at the feedlot and subsequently on days 112, 224, and 361 of the study. The calves were fed a steam- flaked corn-based diets. A receiving diet (2.21 Mcal of NEm/kg DM) was provided during the initial 112 days of feeding. From day 112 until harvest all steers received a finishing diet (2.27 Mcal of NEm/kg DM). Because two different diets were used, two partial (day 1 to day 112 and day 113 to day 361), and one full period (day1 to day 361) feeding periods were evaluated. Statistical differences between the final weights of all the groups were observed, which allowed a profit estimation, obtained by subtracting the purchase cost of calves plus the total feed cost from the revenue obtained from the sale of the steers. Overall weight gain and feed intake were higher with increased ABW, feeding efficiency was better for intermediate ABW groups (112 and 117 kg), with the calves with ABW of 112 kg being the most profitable (USD 15.8 more profit than the 117 Kg. group)
Metabolic profile, antimicrobial and toxicity evaluation of Azadirachta indica roots
Authors: Romão Ana Lúcia Eufrázio , Abreu Katiany do Vale , Fontenelle Raquel Oliveira dos Santos , Silva Ana Luiza Beserra da , Alves Carlucio Roberto
Published: September 2022

ABSTRACT: The constituents of the hydroethanolic extract ofAzadiractaindicaroot were investigated using ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UPLC-QTOOF-MSE). Acute toxicity was evaluated in an experimental animal model. We investigated the antibacterial activities ofA. indicaroots againstSalmonella typhimuriumandStaphylococcus aureusand the antifungal activities against strains ofTrichophyton rubrum, Candida albicansandCandida tropicalis. We identified nine secondary metabolites in the hydroethanolic extract by UPLC-QTOOF-MSE. The extract was highly effective in inhibiting the growth of T. rubrum strains, so it can be effective in combating the dermatophyte tested,but it had no inhibition potential on any bacterial strains orCandidaspecies evaluated. It was possible to infer that the extract had no acute toxicity in relation to the animal model Danio rerio. Therefore, since neem has a high bioactive potential and adapts well to the climate of semiarid regions, growing this species could become a source of income for farmers by its use to produce naturals fungicide and drug, as alternatives to conventional products, which can cause microbiological resistance and/or are toxic to the environment, besides being expensive.
A construção de políticas de saúde para as populações LGBT no Brasil: perspectivas históricas e desafios contemporâneos
Authors: Ferreira Breno de Oliveira , Nascimento Marcos
Published: September 2022

Resumo Este ensaio procura produzir memórias sobre os percursos da construção de políticas de saúde para lésbicas, gays, bissexuais, travestis e transexuais (LGBT) no Brasil, a partir da noção de política sexual. Com base na construção de uma linha do tempo que tem por ponto de partida a criação do Sistema Único de Saúde, o artigo apresenta: as primeiras produções de cuidados em saúde a partir da epidemia de Aids nos anos 1990; como a saúde se torna objeto de políticas públicas, fruto do diálogo governamental com o movimento social organizado, tendo como referência a perspectiva dos direitos humanos e da produção de cidadanização para pessoas dissidentes da cisheteronorma; e por fim, a abordagem de saúde integral como premissa da política de saúde LGBT. Em um momento de avanços de forças conservadoras e de desmonte de direitos, são apontados os desafios atuais para a construção do cuidado integral em saúde que leve em consideração a diversidade sexual e de gênero.
Saúde de lésbicas: experiências do cuidado das enfermeiras da atenção básica
Authors: Milanez Letícia de Sousa , Nabero Ana Paula Pereira , Silva Adriane das Neves , Pedrosa José Ivo dos Santos , Ferreira Breno de Oliveira
Published: September 2022

Resumo As lésbicas se deparam com inúmeras barreiras nos serviços de saúde e vivenciam experiências de preconceito, estigmatização e invisibilização de suas demandas de saúde. Neste artigo, buscou-se compreender os sentidos atribuídos por enfermeiras da atenção básica às práticas de cuidado em saúde com lésbicas. Trata-se de uma pesquisa qualitativa realizada com 15 enfermeiras que atuavam na atenção básica de Teresina, Piauí. A análise foi pautada no referencial teórico de habitus, campo e violência simbólica de Pierre Bourdieu. Observou-se que as práticas das enfermeiras no campo da atenção básica seguem protocolos heteronormativos. Portanto, é essencial que essas enfermeiras possam desenvolver outros habitus, a fim de garantir diferentes formas de identidades dentro dos serviços de saúde.
“Mas a categoria de exposição também tem que respeitar a identidade”: HSH, classificações e disputas na política de Aids
Authors: Calazans Gabriela , Facchini Regina
Published: September 2022

Resumo Este ensaio explora a relação entre diversidade e saúde pública ao abordar tensões que envolvem classificações e reconhecimento no campo das políticas de HIV e Aids. Objetiva refletir sobre como se articulam categorias classificatórias e operativas no âmbito das respostas programáticas em relação à produção social de diferenças e desigualdades. Para tanto, parte do referencial teórico dos estudos sobre vulnerabilidade e reconhecimento e de metodologia que inclui revisão crítica da literatura sobre a categoria HSH e material etnográfico oriundo de pesquisas das autoras e de revisão de literatura, relativo ao movimento social, pesquisas e políticas com foco em lésbicas, gays, bissexuais, travestis e transexuais (LGBT). Recupera o processo de construção da categoria HSH no campo das políticas de prevenção de HIV e Aids em âmbito internacional, situando atores políticos e tensões. Problematiza essas tensões ao analisar processos de produção de sujeitos políticos e mudanças nas relações socioestatais que envolvem LGBT. Enfatiza a importância de considerar como diferenças e desigualdades emergem nos processos sociopolíticos e de destinar estudos para aprimorar políticas, assegurando um cuidado efetivamente mais respeitoso.
Ways and detours in guarantee of health for the black population and the confrontation of racism in Brazil
Authors: Anunciação Diana , Pereira Lucélia Luiz , Silva Hilton P. , Nunes Ana Paula Nogueira , Soares Jaqueline Oliveira
Published: September 2022

Abstract Institutional racism is prevalent in the health services in Brazil and is based on concrete power relations that subjugate, dominate and exclude blacks from having adequate access to health care and health institutions. This critical essay analyzes the importance of expanding the debate, and the production of knowledge about the health of the black population (HBP), focusing on two points: the role of the National Policy for the Integral Health of the Black Population (PNSIPN) and the importance of including the skin color item in the health information systems; and the need for a process of permanent training of professionals, including contents related to the understanding of racism as an element of the social determination of health/disease and heir effects. To demonstrate how structural and institutional racism have affected the black population, we bring also examples of the quilombola populations in the context of the Covid-19 pandemic in the country since 2020. It is concluded that the promotion of care, the reduction of inequities and the quality of health care need to undergo changes in several dimensions, such as the strengthening of the SUS, the daily fight against structural and institutional racism, among others.
Towards an industrial policy for expanding access to health
Authors: Guimarães Reinaldo
Published: September 2022

Abstract The text presents and discusses a new direction of the Unified Health System (SUS) policy geared toward the Health Industrial Complex. A policy aimed at the technological and productive development of public and private companies in the health field flourished from 2007 to 2016 and has been weakened and deformed since then. Despite its success, the so-called Productive Development Policy (PDP) evidenced some weaknesses that must be tackled during its resumption. Besides suggesting this resumption, the text proposes to expand the policy by articulating the primary PDP tool - Public-Private Partnerships - with other related policies that involve the health industry operated by the Ministry of Health.
Cyclosporine A increases the intensity of Toxocara canis infection in swiss mice
Authors: Terto W. D. S. , Moura M. Q. de , Borchardt J. L. , Santos F. D. S. , Avila L. F. da Costa , Pinheiro N. B. , Leite F. P. Leivas , Villela M. M. , Berne M. E. A.
Published: September 2022

Abstract Toxocariasis is a zoonotic disease of worldwide distribution. The connection between parasitic diseases and conditions that depress the immune system, such as the use of immunosuppressive drugs, has been studied. The purpose of this study was to evaluate the effect of Cyclosporine A (CsA) on the intensity of infection, humoral response and gene transcription of interleukins IL-4, IL-10 and IL-12 in mice experimentally infected with Toxocara canis. To this end, mice were divided into two groups treated with CsA (G1: 10 mg/Kg and G2: 50 mg/kg), the G3 and G4 group received PBS. After the last administration of the drug or PBS (orally every 48 hours for 15 days), groups G1, G2 and G3 were inoculated with 1200 eggs of T. canis. Was collected blood samples on days zero, 15 and 30 days post-inoculation (PI), for ELISA test and the mice were euthanized 30 days PI. The organs and striated muscle tissue were collected for the recovery of larvae. The splenocytes were analyzed by RT-PCR. The intensity of infection in the mice treated with 50 mg/kg of CsA was 65.5% higher than in the control group (p=0.001). An analysis of the kinetics of anti-Toxocara antibody revealed that the groups treated with CsA showed significantly higher mean levels of antibodies on day 15 PI. The transcription of the three tested interleukins showed no statistical difference between G2 and G3 (control). It was concluded that the immunosuppression triggered by CsA (50 mg/Kg) favored the establishment of a larger number of T. canis larvae without, however, altering immunoglobulin production and IL-4, IL-10 and IL-12 transcription on day 30 PI.