bluuebunny/crossref_metadata_2025 huggingface dataset:
Neonatal Azithromycin Administration and Growth during Infancy: A Randomized Controlled Trial
Authors: Sie Ali , Bountogo Mamadou , Zakane Alphonse , Compaoré Guillaume , Ouedraogo Thierry , Ouattara Mamadou , Lebas Elodie , Brogdon Jessica , Nyatigo Fanice , O’Brien Kieran S. , Porco Travis C. , Bärnighausen Till , Arnold Benjamin F. , Lietman Thomas M. , Oldenburg Catherine E. , _ _
Published: March 2023

Observational studies have linked early-life antibiotic exposure to increased risk of obesity in children in high income settings. We evaluated whether neonatal antibiotic exposure led to changes in infant growth at 6 months of age in Burkina Faso. Neonates aged 8 to 27 days of age who weighed at least 2,500 g at the time of enrollment were randomized in a 1:1 fashion to a single oral 20-mg/kg dose of azithromycin or equivalent volume of placebo from April 2019 through December 2020. Weight, length, and mid-upper-arm circumference (MUAC) were measured at baseline and 6 months of age. Growth outcomes, including weight gain in grams per day, length change in millimeters per day, and changes in weight-for-age Z-score (WAZ), weight-for-length Z-score (WLZ), length-for-age Z-score (LAZ), and MUAC were compared among neonates randomized to azithromycin compared with placebo. Among 21,832 neonates enrolled in the trial, median age at enrollment was 11 days, and 50% were female. We found no evidence of a difference in weight gain (mean difference −0.009 g/day, 95% confidence interval [CI]: −0.16 to 0.14, P = 0.90), length change (mean difference 0.003 mm/day, 95% CI: −0.002 to 0.007, P = 0.23), or WAZ (mean difference −0.005 SD, 95% CI: −0.03 to 0.02, P = 0.72), WLZ (mean difference −0.01 SD, 95% CI: −0.05 to 0.02, P = 0.39), LAZ (mean difference 0.01, 95% CI: −0.02 to 0.04, P = 0.47), or MUAC (mean difference 0.01 cm, 95% CI: −0.02 to 0.04, P = 0.49). These results do not suggest that azithromycin has growth-promoting properties in infants when administered during the neonatal period.

Trial registration: ClinicalTrials.gov NCT03682653.
A study on ‘Patternicity’-based UX design approach for the ‘Artificial Intelligence-based Vehicle’: focused on Anthropomorphism Design of Autonomous Vehicle
Authors:   Korea Institute of Design Research Society, Na Dae Yol , Nah Ken
Published: March 2023

Artificial intelligence, such as the AlphaGo and ChatGPT, has become popularized and is being incorporated into various robots, and more recently, into autonomous vehicles (referred to as AVs). The phenomenon of anthropomorphism, a part of the patternicity, which is the attribution of human-like characteristics to objects by assigning meaning to them. With the incorporation of AI into various robots and autonomous vehicles, users often feel fear and difficulty in their use due to the unfamiliarity of these products. This study highlights the necessity of communication between cars and humans and among vehicles, with recent AVs seeing a rapid increase in this need. The continuous research on the internal and external displays of AVs meets the communication demands based on AI technology. To make effective use of various AI-based UX design, the new AV design framework for anthropomorphism is proposed, combining status and interface in the vehicle with AI, to create the most harmonious and balanced design. Further study will be required for each models.
A Study on the Effect of Humor Expression in Package Design on Consumers' Purchasing Behavior
Authors:   Korea Institute of Design Research Society, Zhou Nan , Oh Yong Kyun
Published: March 2023

Humor is one of the best ways to convey and express information in modern and contemporary days. Particularly in package design, humor expression can immediately attract consumers' attention and arouse consumers' desire to linger (or stick around) until the final actual purchase. However, since most of the existing studies on humor were on advertising design or product design, there are relatively few studies on humor in package design, so this study aims to explore the effect of humor expression on consumer behavior models (AIDA) in package design. In this study, humor expression was analyzed as 'substituting, combining, and manipulating' through prior theory research, and then actual case analysis was performed. Finally, the collected survey data were empirically analyzed by SPSS.25. The three methods of humor representation in packaging design can actually affect consumers' purchasing behavior, but the most influential one is 'substituting', which can provide a reference theoretical foundation for humor representation in future package design.
The Effects of Visual Characteristics of HMD on VR Contents Engagement
Authors:   Korea Institute of Design Research Society, Cho Yoon Sung
Published: March 2023

There is a growing trend of user demand for highly immersive media that provides a sense of reality. The utility of virtual reality, which is expected to be a promising industry, arises from the interaction process of user interest, participation, and immersion. Therefore, the concept of engagement, which leads to user behavior by eliciting their experiences and interests, is crucial in determining the success of virtual reality content. Effective application of the concept of engagement is necessary at this point. This study aims to analyze the relationship between the visual characteristics of HMD, the sense of reality of virtual reality content, and media engagement to develop efficient user experience design strategies that enhance engagement in virtual reality content. Through a review of previous studies, we derived each characteristic factor and conducted a survey/statistical analysis of the relationships between them. As a result, we concluded that the visual characteristics of HMD have a significant impact on the sense of reality of virtual reality content. Additionally, it was analyzed that interactivity, media invisibility, and current event factors among the factors affecting the sense of reality in virtual reality have a significant impact on immersion, interest, and attention. In the competition of deepening sense of reality-based services, we expect virtual reality technology to actively utilize the engagement factors of virtual reality content and contribute to the development of virtual reality content that integrates various media.
Epigenetic Analysis of Long-term Epilepsy-Associated Tumors by Methylation-Specific Multiplex Ligation-dependent Probe Amplification
Authors: Jesus-Ribeiro Joana , Ribeiro Ilda Patrícia , Pires Luis Miguel , Rebelo Olinda , Pereira Ricardo , Bento Conceição , Sales Francisco , Santana Isabel , Freire António , Barbosa Melo Joana
Published: March 2023

Introduction: Ganglioglioma and dysembryoplastic neuroepithelial tumor represent the most common neoplasms in the group of long-term epilepsy-associated tumors. Mapping of epigenetic alterations, particularly DNA methylation, has recently been shown to offer promising perspectives in brain tumors, identifying key genes that may serve as potential diagnostic biomarkers. We aim to perform a genetic and epigenetic analysis using long-term epilepsy-associated tumors’ tissue, to contribute to the identification of such biomarkers.

Methods: DNA copy number alterations and methylation status in genes relevant to tumorigeneses were analyzed by methylation-specific multiplex ligation-dependent probe amplification using fresh frozen postoperative tissue obtained from epilepsy surgery.

Results: From the six tumors included in the study (three gangliogliomas and three dysembryoplastic neuroepithelial tumors), one ganglioglioma harboring a BRAF:p.V600E mutation presented changes in methylation status. This particularly patient had a focal epilepsy with video-electroencephalogram (EEG) reveling an ictal pattern in the right occipito-parietal region. Brain magnetic resonance imaging revealed a right mesial temporal lesion. His seizure frequency increased despite antiepileptic treatment and two years later he underwent his first surgery. Two more surgeries were performed years later due to seizure recurrence associated to an increase of the residual tumor. Postsurgical Engel class is IIA at three years of follow-up. Copy number losses were detected in chromosomes 1p (TP73), 2p (MSH6), 3p (VHL), 10p (CREM), 11q (GSTP1), 12q (CHFR), 14q (MLH3), 16p (PYCARD), 17p (TP53), 17q (BRCA1) and 19p (STK11). Copy number gains were detected in chromosome 11p (CD44). The MGMT (58%) and CD44 (51%) genes were methylated.

Conclusion: A high number of chromosomal aberrations were identified in one ganglioglioma, among which deletions dominated, reinforcing the spectrum of chromosomal abnormalities previously described. We observed copy number gain and methylation in CD44, which contributes to cell-cell/cell-matrix interactions. The methylation of MGMT, involved in DNA repair, is concordant to other studies. Our data highlight the importance of unravel new chromosomal imbalances and the role of DNA methylation in theses tumors, which may provide more arguments in favor of an integrative histological and (epi)genetic classification.
X-Linked Adrenoleukodystrophy: A Heterogeneous Peroxisomal Disorder you Should Not Miss
Authors: Lopes das Neves Pedro , Durães João , Monteiro Isabel , Diogo Luísa , Macário Maria do Carmo
Published: March 2023

X-linked adrenoleukodystrophy (X-ALD) is a rare peroxisomal disease caused by a mutation in gene ABCD1, impairing peroxisomal b-oxidation of very long-chain fatty acids. It has a heterogeneous clinical presentation that may difficult the diagnosis, with three main phenotypes: an Addison syndrome-like phenotype with adrenal insufficiency; a myeloneuropathic form, which progresses as a spastic paraparesis; a cerebral form with potentially extensive brain demyelination. Females can present with a phenotype resembling the myeloneuropathic form, but with a slow progression. Prompt recognition and diagnosis are essential, as allogenic hematopoietic stem cell transplantation can be offered for the cerebral form of the disease, the phenotype with the worst prognosis.

We present four clinical cases of patients followed in our neurometabolic reference centre with X-ALD, highlighting different clinical presentations, diagnostic workup, management and possible clues for the diagnosis.
Prediction of suicidal tendencies using machine learning
Authors: Gourab Karak  , Kishalay Ghosh  , Nur Muktada Hasan Ansari  , Sulekha Das  , Avijit Kumar Chaudhuri
Published: March 2023

Suicide is nowadays a crucial public health issue. In various communities, people are much more affected by this severe tendency. Nowadays, suicide connects to mental illness. Along with depression, drug misuse is an equally important risk factor. Although anxiety, personality, and trauma-related issues, as well as genetic and mental disorders, also equally contributed to this health issue. This research work conducts to find the relation among suicidal tendencies, depression, anxiety, daily stresses, and mental health among all people, including employees, non-employee, students, old age, and all others. Step-by-step multiple linear regression, logistic regression analyses, confusion matrix, and cross-validation use for the data analysis. Suicidal illusions have a significant and positive relation with depression, anxiety, mental stress, and drug use disorder. In this research work regression technique showed that depression is the most crucial feature in the prediction of suicidal behavior, where anxiety, mental health, and daily stresses are the next, followed by respectively. Psychological problems and mental health issues with other factors such as gender problems, marital problems, and hallucinations play a role in suicidal thoughts [1]. Through this research, approximately 84 percent (%) of the data predict correctly.
Prediction of Blood Pressure and Cholesterol By Machine Learning Technique
Authors: Dip Das  , Arnam Ghosh  , Aishik Banerjee  , Sulekha Das  , Avijit Kumar Chaudhuri
Published: March 2023

Blood pressure (BP) is the pressure of circulating blood against the walls of blood vessels. Cholesterol is any of a class of certain organic particles called lipids [1]. High blood pressure along with high cholesterol are two of the main causes of heart disease. Heart disease, stroke, and other cardiovascular (blood vessel) diseases are among the primary cause of death. Approximately 10 million people every year die having high blood pressure and it was found that 6 in 10 Indians have abnormal levels of blood cholesterol [2]. An increase in blood cholesterol signifies an increase in a man's blood pressure, which can easily lead to abnormal blood pressure,e.g. high blood pressure. Generally, Prediction refers to the output of an algorithm after it has been trained on a dataset. Here Authors tried to predict whether a sample can have blood pressure and cholesterol or both present or not by analyzing some datasets. Generally, for making these types of predictions, machine learning algorithms are a very appropriate and most-used technique. A Multiple Linear Regression was applied in this study. Data has been analyzed through Multiple Linear Regression Analysis (MRA). The proposed model is tested on a Primary Data Set, prepared by Techno Engineering College Banipur’s students, and the relevant data of this Dataset has been collected from some districts in West Bengal, India. Through this research, approximately 76 percent of the data was predicted correctly.
Assertiveness as a New Strategy for Physical Education Students to Maintain Academic Performance
Authors: Blegur Jusuf , Haq Aniq Hudiyah Bil , Barida Muya
Published: March 2023

Serious problems occur in social life. In several cases in Indonesia, students often abuse their group collectivity and social relations with disciplinary behaviour such as following peer persuasion to spend much time hangout so that students neglect to manage study time, complete study assignments, and even be absent from lectures.. However, other students have managed to control unproductive social relations (persuasion to hang out during class hours, inducement not to do coursework, and others) to stabilize their academic performance with assertiveness. This explore student assertiveness strategies. At the same time, they were projecting strategic assertiveness protocols to maintain their academic performance. This qualitative study involved 11 purposefully sampled university students. Student assertiveness strategies were explored using observation, interview, and documentation techniques. Spardley’s (1979) domain analysis technique and Miles and Huberman's (1994) analytical procedure were used to find meaning and project assertive syntax. The study results suggest that students tend to show assertiveness, permissiveness, and aggressiveness in effective dialogue, constructive feedback, conflict resolution, and non-verbal communication domains. However, students who had good academic performance were more effective in using assertiveness. Furthermore, our study identified six strategic models (syntax) that students use to maintain their academic performance, namely: (1) being open, objective, and rational in expressing their aspirations, (2) being firm and brave when making decisions, (3) believing in one's abilities, (4) prioritizing priorities, (5) carry out obligations without disturbing the rights of other colleagues, and (6) accept differences of opinion/views. As a result, students can use assertiveness to maintain and control destructive behaviour in their environment and social relations to remain achievers while keeping being friendly in maintaining and building social relationships. Lecturers and administrators need to do assertive training and assistance to their students on an ongoing basis so that students have additional soft skills that help them succeed in the academic field and the future.
Harmony of National and Universal Values in Uzbekistan
Authors: Sobirovich Turdiyev Bexruz , Mundo Norman Zoncita Del
Published: March 2023

This article studies the process of improving the relationship between national and universal values in the development of a democratic society, the socio-philosophical analysis of the role of SDGs and priorities and principles of the strategy of spiritual renewal. Moreover, article clarifies the process of transformation national and universal values and its influence to the uprising of Uzbek cultural heritage.
INSIGHTFUL APPLICATION OF HERBAL EXTRACTS IN THE PREVENTION AND TREATMENT OF ANIMAL DISEASES AND IMPROVEMENT OF MEAT QUALITY AND SAFETY
Authors:   University of Kragujevac, Faculty of Agronomy, Serbia, Kurćubić Vladimir , Stajić Slaviša ,   University of Belgrade, Faculty of Agriculture, Serbia, Miletić Nemanja ,   University of Kragujevac, Faculty of Agronomy, Serbia, Petković Marko ,   University of Kragujevac, Faculty of Agronomy, Serbia
Published: March 2023

In an indirect way, through animal nutrition or selection, we can influence the composition and quality of muscle and fat tissue, and thus the nutritional and functional value of meat. The process is longer and is not fully controlled yet. Direct processes improve nutritional properties by adding components with functional properties and/or reducing or removing ingredients that may negatively affect health. Herbal raw materials and extracts, by-products and wastes from fruit and vegetable processing can modify feed in order to achieve a stable health status and preserve animal well-being and sensory quality of meat, with an extended shelf life.
THE EFFECT OF THE REARING SYSTEM AND GENOTYPE OF LAYING HENS ON FATTY ACID COMPOSITION OF EGGS
Authors:   University of Kragujevac, Faculty of Agronomy, Serbia, Rakonjac Simeon , Bogosavljević-Bošković Snežana ,   University of Kragujevac, Faculty of Agronomy, Serbia, Dosković Vladimir ,   University of Kragujevac, Faculty of Agronomy, Serbia, Lukić Miloš ,   Institite for Animal Husabandry Belgrade-Zemun, Serbia, Škrbić Zdenka ,   Institite for Animal Husabandry Belgrade-Zemun, Serbia, Petričević Veselin ,   Institite for Animal Husabandry Belgrade-Zemun, Serbia, Petrović Milun D. ,   University of Kragujevac, Faculty of Agronomy, Serbia
Published: March 2023

This paper aimed to determine the effect of the rearing system and genotype of laying hens on the fatty acid composition of eggs. Seven times during the one-year production cycle, 15 eggs from all four experimental groups were taken, and fatty acid composition was determined on pooled samples. Based on the obtained results, it can be concluded that the highest content of SFA had organic New Hampshire eggs, MUFA organic Isa Brown eggs and PUFA floorproduced eggs. Regarding the ratio of n-6:n-3 PUFA, it can be noted that the organic eggs had a lower ratio compared to the floor eggs, as well as the New Hampshire breed compared to the Isa Brown hybrid.
PROPOSAL OF NEW DATASET FOR CHILD FACE EXPRESSION RECOGNITION AND COMPARISON OF DEEP LEARNING MODELS ON THE PROPOSED DATASET
Authors: SAYIN İrem , AKSOY Bekir
Published: March 2023

With the developing technology, smart systems have started to take place in our daily lives. Accordingly, it is very important for the systems that will actively participate in social life to adapt to social life properly. One of the most important steps of adapting to social life is communication. Facial expressions are one of the most important parts of communication that usually supports verbal communication. For this reason, many studies have been carried out on identifying facial expressions. The vast majority of these studies were carried out using datasets containing only adult faces. Conducting studies that do not involve the elderly and children may lead to the creation and development of highly biased smart systems. Therefore, this article focuses on detecting children's facial expressions. In order to detect facial expressions in children, a data set was prepared with images collected from search engines using keywords. By using the transfer learning method, the success of VGG16, ResNet50, DenseNet121, InceptionV3, InceptionResNetV2 and Xception models were evaluated and compared on this prepared data set. According to the evaluation results, the best result was obtained with the InceptionV3 model with an accuracy rate of 76.3% and an F1 score of 0.76.
Effects of Dietary Momordica Charantia Supplementations on Broiler Performance, Blood Parameters, Meat Quality, and Intestinal Morphology
Authors: YENİCE Güler , ATASEVER Mustafa , KARA Adem , ÖZKANLAR Seçkin , URÇAR GELEN Sevda , GEDİKLİ Semin
Published: March 2023

Momordica charantia (MC) is one of the most often used medicinal plants, a rich source of vitamins and minerals. This study aimed to assess the effects of a food supplementation of MC extract at various doses (0, 0.15, 0.30, 0.45 g kg-1) on the performance, carcass yield, meat quality, intestinal morphology, and some blood parameters in broilers. A total of 288 Ross 308 broiler chicks (1 day old) were used in the experiment. Animals were divided into 4 groups with 6 replicates. Feed intake (FI), daily weight gain (DWG), feed conversion rate (FCR), and carcass yield were unaffected by MC extract supplementations. The group treated with a high dosage of MC extract had significantly lower serum phosphor (P) levels than the other groups (P
Türkiye's Offshore Hybrid Energy Potential and Cost Estimation in the Eastern Mediterranean
Authors: ÇELİKDEMİR Soner , ÖZDEMİR Mahmut Temel
Published: March 2023

The major target of this study is to determine the hybrid energy potential, as a renewable energy source, in the Eastern Mediterranean region. The most important motivation of this study is that the Eastern Mediterranean zone has a significant hydrocarbon potential in addition to its geopolitical value. Hence, the hydrocarbon platforms in the region constitute the main framework of this novel research. Wind, solar and wave energy potentials and cost estimation of 6 selected locations in the Eastern Mediterranean are analyzed. The analysis is based on the needs of the platforms, i.e. if the energy is produced more than the needs of the platforms, the hydrogen is produced by electrolysis. The cost estimation of the system is carried out by assuming not only the situation of the produced hydrogen but also the transportation of the hydrogen to the mainland. According the results of the analyzes, it has been shown that the Eastern Mediterranean has a very high wind, solar, and wave energy potential due to the fact that Crete and Rhodes Islands form a natural strait. As a conclusion different transmission scenarios of the hydrogen to the mainland shows that the energy required by the platforms can be provided by renewable energy sources, regardless of their power.
Farklı Mineral Katkı Oranlarına Göre Üretilen Harç Numunelerin Radyasyon Perdeleme Özelliklerinin Belirlenmesinde Teorik Analiz
Authors: KÜÇÜKÖNDER Adnan , ALKILINÇ İbrahim , BİBER TEMİRCİK Şeyma , ZENGİN Başak
Published: March 2023

Bu çalışmada farklı mineral malzemelerle matrisleri hazırlanan takviyeli harçların radyasyon perdeleme özellikleri incelenmiştir. Harç numunelerinin radyasyona karşı gösterecekleri davranışı belirleyemek için harç numunelerinde farklı özelliklere sahip mineral katkılar kullanılarak üretimler yapılmıştır.

Yapı sektöründe yaygın kullanılan perlit, kolemanit, pomza, silis dumanı, uçucu kül, öğütülmüş yüksek fırın cürufu tercih edilmiştir. Üretilen numunelerin radyasyon perdeleme özelliklerini araştırabilmek için ise kütle soğurma katsayıları (µ cm-1) XCOM programında 59.543 KeV enerjide hesaplanmıştır.

Çalışmanın sonuçlarının sağlıklı bir şekilde elde edildiğini kanıtlayabilmek için daha önce yapılmış deney verileriyle teorik çalışma verileri karşılaştırılmıştır. Deneysel sonuçlarla teorik sonuçlar karşılaştırıldığında ise iki yöntem arasında iyi bir uyum olduğu elde edilmiştir.
Determination of Gamma Radiation Shielding Characteristics for Some Iron-Based Metallic Glasses
Authors: AKMAN Ferdi
Published: March 2023

In this study, the gamma radiation shielding characteristics of metallic glasses having Fe81B13.5Si3.5C2, Fe79B16Si5, Fe78B13Si9 and Fe40Ni38B18Mo4 components and coded as FeBSiC, FeBSi1, FeBSi2 and FeNiBMo were investigated. In order to investigate, the mass attenuation coefficients for metallic glasses in the photon energies range of 0.060 to 2.614 MeV were calculated with the help of WinXCOM program and GEANT4 and FLUKA simulation codes. The linear attenuation coefficient, half and tenth value layers, mean free path, effective atomic number and electron density parameters were calculated with the help of the calculated mass attenuation coefficients. Variations of the calculated gamma radiation shielding parameters with photon energy were discussed. It was observed that mass and linear attenuation coefficients, effective atomic number and electron density parameters decreased with increasing photon energy, while half and tenth value layers and mean free path parameters increased with increasing photon energy. It has been observed that metallic glasses have better gamma shielding capabilities in the low photon energy region, and metallic glass coded as FeNiBMo has better gamma radiation shielding capacity than other studied metallic glasses.
The Study of 2, 4-Diamino-6-methly-1, 3, 5-triazine on the Corrosion Inhibition of Mild Steel in The Hydrochloric Acid Medium: Integrated Theoretical and Experimental Investigations
Authors: YILDIZ Reşit
Published: March 2023

The aim of this study is the investigation of adsorption and corrosion behaviors of 2,4-Diamino-6-methly-1,3,5-triazine (2-DMT) on mild steel (MS) in 0.5 M HCI solution using many experimental and theoretical studies such as potentiodynamic polarization, electrochemical impedance spectroscopy (EIS), linear polarization resistance (LPR), adsorption isotherm, potential of zero charge (PZC), scanning electron (SEM), atomic force microscopies (AFM) and quantum chemical calculations. The results showed that 2-DMT has an outstanding anti-corrosion performance of 94.6% at an optimum concentration of 10 mM and the MS surface, which was exposed to the inhibited solution at 298 K, does not contain pits, cracks or deformations. Values of icorr are found to be 0.51, 0.22, 0.098, 0.072 and 0.039 mA cm-2 for blank solution and each concentration of 2-DMT. Hydrogen volumes are 90 and 4.6 mL cm-2 for blank solution and the existence of 10.0 mM 2-DMT, respectively. The observed adsorption is much more consistent with Langmuir. The high performance is explained by the effective adsorbing of organic matter to the MS surface. HOMO, LUMO energies and the energy gap (∆E) are -7.1980, -1.9959 and 5.2021 eV, respectively. Accordingly, it is suggested that this organic compound can be used in the industrial acid cleaning procedure.
Investigation of Some Metabolic Enzyme Activities in Samples of Serum and Humor Aqueous of Cataract Cases with Pseudoexfoliation Syndrome
Authors: ÇALIŞKAN Büşra , AKSOY Mine , ÖZASLAN Muhammet Serhat , AKYOL SALMAN İlknur
Published: March 2023

Objective: Pseudoexfoliation syndrome (PEX) occurs as a result of aggregation of extracellular matrix material in ocular tissues and visceral organs and it is known as a systemic disease. The purpose of our study is to investigate the activities of carbonic anhydrase (CA), glutathione reductase (GR), aldose reductase (AR), paraoxonase (PON) enzymes in aqueous and serum samples, also serum selenium levels.

Methods: Serum and aqueous samples from 33 PEX and 33 control subjects were collected. Enzyme activities were studied in both serum and aqueous samples by biochemical methods.

Results: According to the results, serum CA hydratase enzyme activity levels were higher in the samples with PEX compared to the control samples (p < 0.05). Aqueous CA hydratase and aqueous/serum PON, GR and AR activity levels did not differ significantly among the study samples (p > 0.05).

Conclusions: Based on the relationship of carbonic anhydrase with aqueous production and glaucoma, increased CA hydratase activity may help to understand the etiopathogenesis and mechanism of conversion to glaucoma of PEX. In the literature, we did not find a study on activity of CA in aqueous and serum samples in patients with PEX. Therefore, we believe that this study can be a reference.
Increasing Tourism Image through the Tourism Marketing Development Program Implementation in Bandung City
Authors:   Padjadjaran University, Bandung, Indonesian, Rachmawati Santi , Setiawan Tomi ,   Padjadjaran University, Bandung, Indonesian, Ismanto Slamet Usman ,   Padjadjaran University, Bandung, Indonesian
Published: March 2023

This study describes the implementation of a marketing development program by the Culture and Tourism Office of Bandung City to increase the tourism destination image, which impacts the increasing number of tourist visits and local revenue. However, this program is different from what was expected. The research employs a qualitative approach and data collection methods using observation, interviews, documents, and literature studies. The research uses data analysis techniques with three stages: data condensation, data presentation, and conclusion and verification. The results of this study indicate that the implementation of the tourism marketing development program by the Culture and Tourism Office of Bandung has not been run optimally in terms of the program’s implementation elements and environmental factors. From the standpoint of the program overview, the budget and infrastructure facilities are still inadequate. From the implementation aspect, the process of implementation lacks employees, and cooperation with tourism partners has not gone well. Moreover, on the environmental part, many social issues still occur in the surrounding community that affects the implementation of the program.
Do Workers Feel Satisfied Inside Foreign Companies Established in Tunisia after the Arab Spring Revolution?
Authors:   Faculty of Humanities and Social Sciences of Tunis, University of Tunis 1, Tunisia, Bahri Noomen
Published: March 2023

This paper examines the situation of Tunisian workers in foreign companies established in Tunisia over the period 2019–2022. The methodology of the study depends on the quantitative and qualitative method, both of which are based on experience and monitoring results and statistics. The results indicate that the situation of workers within these institutions ranges between satisfaction and dissatisfaction. It is not good in view of the level of low wages, and it is not bad in view of the availability of a minimum suitable work environment. Several policies are proposed and discussed.
Fasciolous invasion as a sanitary and hygienic threat to the population and animal husbandry in the subjects of the Caspian region of Russia
Authors: Kabardiev Sadrutdin Sh. , Bittirov Anatoly M. , Aliev Ayub Yu. , Aigubova Sabina A.
Published: March 2023

Introduction. WHO considers human fascioliasis to be a global epidemic threat of a parasitic nature.
Materials and methods. The studies were carried out using methods of in vivo diagnostics used in medical and veterinary parasitology (the method of successive washings of feces; the Fülleborn method or the flotation-sedimentation method by Demidov) in relation to samples of feces and soils. In total, in six subjects of Russia to study the spread of fascioliasis in animals in the conditions of slaughterhouses, there were examine the liver in 1800 heads of slaughter sheep, 700 heads of goats, 1000 heads of cows and only 6000 soil samples for the detection of Fasciola hepatica eggs.
In 2011–2019, medical services of 6 subjects of the Caspian region in 21 settlements carried out scatological diagnostics of the population aged 8 to 65 years, in the amount of 25 thousand people, to clarify the incidence of human fascioliasis. The results of the studies were statistically processed according to the method of N.A. Plokhinsky using the software Microsoft Excel 2008. The occurrence index – the percentage of individuals or eggs of F. hepatica in relation to the total number of examined objects – was based on monitoring and analysis of reports from regional divisions of the Federal Service
for Supervision in Protection of the Rights of Consumer and Man Wellbeing (Rospotrebnadzor) and the Department of Veterinary Medicine of the Ministry of Agriculture of Russia for 2011–2019.
Results. Coproovoscopy of 25 thousand samples of faeces for the presence of eggs of the pathogen of fascioliasis, taken from the population of 21 cities of the Caspian region of the Russian Federation, revealed their absence. The trend in the index of occurrence of goat fascioliasis in 2011–2019. had an annual growth trend of 0.03%; in sheep by 0.06%; in cattle by 0.05%, which also characterizes the lack of control measures.
In 6 Republics of the Caspian region, the indices of occurrence and abundance of fascioliasis in goats, sheep and cows increased by 2–2.5 times, which indicates the threat of invasion to the development of livestock industries. Soil samples taken for research were contaminated with invasive elements of Fasciola hepatica in 100% of cases.
Conclusion. The occurrence and abundance indices of F. hepatica eggs were found to be 0, which indicates epidemic well-being in relation to zoonosis. Research conducted indicate to the gain in the incidence index of fascioliasis in goats, sheep, and cows. The 100% contamination of the territories of rural pastures and remote mountain pastures with invasive elements of Fasciola hepatica is a biological and sanitary-hygienic threat to livestock and the population of the Caspian region of Russia.
On accounting for emissions of pollutants from autonomous heat supply sources of individual residential buildings when conducting summary calculations of atmospheric air pollution for settlements
Authors: Volkodaeva Marina V. , Karelin Aleksandr O. , Lomtev Aleksey Yu. , Kanchan Yakov S. , Levkin Andrey V. , Timin Sergey D.
Published: March 2023

Introduction. Autonomous sources of heat supply (ASHS) can make a crucial contribution to the level of atmospheric air pollution in settlements. However, emissions from ASHS in most cases are either not included in the summary calculations of atmospheric air pollution at all or estimated with significant uncertainties.
The purpose of this study was a hygienic assessment of methods and results of accounting for emissions of pollutants from the ASHS of individual residential buildings when conducting summary calculations of atmospheric air pollution for settlements.
Materials and methods. the original methodology of a phased survey of the city’s ASHS was used and the results of summary calculations of atmospheric air pollution in 18 cities conducted using this methodology are presented. Calculations of single, average seasonal (for the cold period) and average annual surface concentrations of pollutants were carried out in accordance with current regulatory documents using the unified software for calculating atmospheric pollution (UPRZA) “Ecologist-city”. In all the studied cities a significant number of sources of atmospheric air pollution was established to be ASHS. In more than 90% of these sources, coal and firewood were used as energy carriers. The greatest excess of hygienic standards of atmospheric air quality was noted
for benz(a)pyrene. In 15 cities, the highest calculated maximum single surface concentration of at least one pollutant created by emissions from ASHS exceeded the maximum allowable single concentration (MACs).
Limitations of the study are due to the fact that direct instrumental measurements to determine the characteristics of emissions from ASHS into the atmosphere are impossible.
Conclusions. The area of the city’s territory where the estimated maximum single surface concentration of at least one pollutant exceeded the MACs, reached 45%, and the seasonal average concentration exceeded maximum allowable average annual concentration on 50% of the territory. The most effective measure to reduce air pollution by emissions from ASHS is the replacement of solid and liquid mineral fuels with natural gas. Unification of methods of accounting and inventory of ASHS as sources of atmospheric air pollution is required.
Reactivity of the autonomic nervous system in children of younger school age with mental retardation
Authors: Smirnova Olga V. , Ovcharenko Elizaveta S. , Kasparov Edvard V. , Fefelova Vera V.
Published: March 2023

Introduction. The functioning of the autonomic nervous system (ANS) to some extent affects various aspects of human health and general well-being. One of the main ANS functions is to ensure adaptation to the factors of the external and internal environment, carried out by the coordinated activity of the sympathetic and parasympathetic links. Determining the predominant type of ANS reactivity according to the characteristics of the heart rhythm makes it possible to predict the adaptive capabilities of the child’s body in the learning process in a personalized way.
The aim of the study was to study the trend in heart rate variability in children with special health conditions associated with disorders of the intellectual development, which characterizes the implementation of mechanisms for adapting the body to the conditions of schooling.
Materials and methods. We examined one hundred sixty eight 7–11 years children of primary school age, including 54 children with special health abilities (SHA) (F70, F71), and 114 mentally healthy children. The study of heart rate variability was carried out using the hardware-software complex “ORTO Valeo”. There was analyzed TP, HF, LF, VLF, LF / HF; RMSSD, SDNN, Mo, AMo, ΔX, IN, AMo / Mo, Amo / ΔX; type of vegetative regulation.
Results. In SHA children of primary school age, the LF, VLF, LF / HF indices are increased and HF is decreased relative to the control group, which indicates the predominance of the sympathetic link of the autonomic nervous system over the parasympathetic. When analyzing the spectral components in SHA children of primary school age, VLF (40.6%) and low HF (19.6%) dominate. According to the types of autonomic regulation in SHA children, the following ratio was found 50: 4: 33: 13, the central type of cardiac regulation dominates (type I).
Limitations. The limitation of the study is due to the specifics of the individuals in the observation group – children of primary school age (7–11 years) with special health opportunities associated with mental retardation.
Conclusion. SHA children of primary school age have high activity of sympathetic modulation, reduced resistance to stress, high tension of adaptive responses with the dominance of the central type of regulation of the cardiac activity. The revealed imbalance of the parameters of autonomic regulation in SHA children without corrective measures (including correction of physical status, psychoemotional and educational loads) threatens the development of a breakdown of adaptive responses to the effects of various internal and external factors, contributing to asthenization of regulatory systems.
The Role of Parents in Their Children’s Education
Authors: Okello Millicent
Published: March 2023

Purpose: The purpose of this study is to investigate the role of parents in their children’s education.

Methodology: The study adopted a desktop research methodology. Desk research refers to secondary data or that which can be collected without fieldwork. Desk research is basically involved in collecting data from existing resources hence it is often considered a low cost technique as compared to field research, as the main cost is involved in executive’s time, telephone charges and directories. Thus, the study relied on already published studies, reports and statistics. This secondary data was easily accessed through the online journals and library.

Findings: The findings revealed that there exists a contextual and methodological gap relating to the role of parents in their children’s education. Preliminary empirical review revealed that education in the premises of a family life, has a double meaning: it must be seen through the perspective of its contribution to the overall child raising up and education, which is crucial to his/her proper formation of children’s personality and further on, his/her preparation for leading an independent life.

Unique Contribution to Theory, Practice and Policy: The Expectancy Value theory and the Ecological Systems theory may be used to anchor future studies on the role of parents in their children’s education. The focus must be put on the family as whole, and the role of children which must be based on their approach and contribution concerning family problems, which should be dealt with, and finally solved by them. Offering education support to children from their parents, concerning issues such as homework, would help
Validación de un instrumento para medir las medidas de bioseguridad del SARS COV 2 en la consulta odontológica.
Authors: Uruchima Orellana Mayra Stefanie
Published: March 2023

Introducción: El SARS-CoV-2 está caracterizado por generar síntomas respiratorios,tos, fiebre y en algunos casos anosmia y disgeusia, que pueden preceder los síntomasrespiratorios. Esta patología presenta un alto riesgo de contagio mediante inhalación ocontacto directo con aerosoles, sangre o saliva. Sin embargo, la transmisión no se limitaexclusivamente al tracto respiratorio, sino que también puede darse por vía ocular ysujetos sintomáticos y asintomáticos pueden ser contagiosos. Objetivo: Validar uninstrumento para medir las medidas de bioseguridad aplicadas para el SAR-COV2durante la consulta odontológica. Materiales y métodos: Este es un estudio descriptivo,prospectivo y cuantitativo-cualitativo. La validación de contenido se realizó a través deljuicio de expertos. Se seleccionaron 5 jueces, quienes revisaron el planteamiento de laspreguntas según los criterios de validez, pertinencia y coherencia. Dando una rúbrica deconfiabilidad y observaciones de parte de cada uno de los evaluadores expertos.Resultado: El resultado obtenido por los diferentes trayectos para evaluar el test fueadecuado, consiguiendo un instrumento de 26 preguntas; siendo válido y muy confiable,según la rúbrica de confiabilidad dada por la suma de los resultados de los instrumentoscuantitativos, habiendo dado este de 91,86sobre 100 justificando su uso y aplicación enel ámbito investigativo Conclusión: El instrumento es aptos para aplicar en un estudioque busque medir bioseguridad aplicadas para el SAR-COV2 durante la consultaodontológica
Halkla İlişkilerin Gazetelerdeki Temsili: The New York Times ve The Guardian Gazeteleri Üzerine İnceleme
Authors: ARTAN ÖZORAN Beris
Published: March 2023

Halkla ilişkiler “algı yönetimi”, “spin doctor”, “zihin yönlendiriciliği”, “kanaat imalatçılığı” gibi kavramlarla eş olarak ele alınmakta, alana yönelik olumsuz bir algı bulunmaktadır. Halkla ilişkiler alanı gerçeği çarpıtan, değiştiren ve kendi çalıştığı kişi ve kurumların lehine döndüren bir alan olmakla eleştirilmektedir. Alana yönelik olumsuz tutumların bir nedeni halkla ilişkilerin medyada temsilidir. Bu çalışmada halkla ilişkilerin iki farklı ülke gazetesi olan New York Times ve The Guardian gazetelerindeki temsillerinin incelenmesi amaçlanmaktadır. Araştırmada bu gazetelerde yer alan ve içinde “halkla ilişkiler” sözcüğü geçen haberler karma yöntem kullanılarak incelenmiştir. Öncelikle içerik analizi yöntemiyle kategoriler belirlenmiş ve halkla ilişkilerin hangi bağlamda kullanıldığı ve alana yönelik oluşturulan duygu (pozitif, nötr, negatif) araştırılmıştır. Daha sonra metin madenciliği yöntemiyle “halkla ilişkiler” sözcüğü ile birlikte kullanılan kavramlar ve içinde halkla ilişkiler geçen haberlerde en çok kullanılan sözcükler incelenmiştir. Araştırma sonucunda halkla ilişkilerin en çok “halkla ilişkiler uzmanı”, “gerçeğin karşısında halkla ilişkiler” ve “olumsuz bir kavram olarak halkla ilişkiler” kategorileri çerçevesinde yer aldığı, haberlerin neredeyse yarısında halkla ilişkilerle ilgili negatif bir duygu oluşturulduğu görülmüştür. Temsil konusunda iki gazete arasında da fark olduğu ortaya çıkmıştır.
Comparative characteristics of plant protection against copper and sulphur influence
Authors: Skura Eugen , Koto Romina , Lika Erinda , Shahini Shpend , Sallaku Fatbardh
Published: March 2023

Efficient agriculture provides not only food security but also improves the economy of the country. Despite the existence of different types of agricultural production (traditional or organic), plant protection is currently a necessary component. Copper and sulphur are effective against pests and improve the quality and quantity of crops, but are toxic and harm the environment, biodiversity, and human health. The purpose of the study is to investigate the current situation regarding the use of copper and sulphur in plant protection in the Republic of Albania and other countries of the Balkan Peninsula and Europe. Theoretical and empirical research methods were used in the study. As a result, it was determined that the studied elements were actively used in different European countries, both in traditional and organic agriculture. There is a tendency to reduce the norms of use, and in some countries – the removal of these chemical elements from plant protection programmes. The paper includes a comparative characteristic of the use of copper and sulphur and a survey among Albanian agricultural producers on the use of preparations based on these elements. It is established that in the republic, copper and sulphur are actively used mainly in the form of herbicides and fungicides. They are used on vegetable and fruit crops, as well as grapes and olives. There is a problem of informing producers about the negative impact of copper and sulphur on the environment and human safety, as well as control by the state. The practical significance of the study lies in the analysis of the current situation of copper and sulphur use in Albania and in the identification of ways to change it for the better