bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 3 from CIP2A Modulates Cell-Cycle Progression in Human Cancer Cells by Regulating the Stability and Activity of Plk1
Authors: Kim Jae-Sung , Kim Eun Ju , Oh Jeong Su , Park In-Chul , Hwang Sang-Gu
Published: March 2023

PDF file, 89K, CIP2A-mediated mitotic regulation is independent of PP2A.
Supplementary Figure 1B from CIP2A Modulates Cell-Cycle Progression in Human Cancer Cells by Regulating the Stability and Activity of Plk1
Authors: Kim Jae-Sung , Kim Eun Ju , Oh Jeong Su , Park In-Chul , Hwang Sang-Gu
Published: March 2023

PDF file, 962K, Immunohistochemical analysis of CIP2A and Plk1 expression in various human cancer specimens.
Supplementary Figure 3 from Trastuzumab-Resistant Cells Rely on a HER2-PI3K-FoxO-Survivin Axis and Are Sensitive to PI3K Inhibitors
Authors: Chakrabarty Anindita , Bhola Neil E. , Sutton Cammie , Ghosh Ritwik , Kuba María Gabriela , Dave Bhuvanesh , Chang Jenny C. , Arteaga Carlos L.
Published: March 2023

PDF file - 123K, Inhibition of CSC fraction by trastuzumab in sensitive but not resistant cells
Supplementary File 1 from Tasquinimod Is an Allosteric Modulator of HDAC4 Survival Signaling within the Compromised Cancer Microenvironment
Authors: Isaacs John T. , Antony Lizamma , Dalrymple Susan L. , Brennen W. Nathaniel , Gerber Stephanie , Hammers Hans , Wissing Michel , Kachhap Sushant , Luo Jun , Xing Li , Björk Per , Olsson Anders , Björk Anders , Leanderson Tomas
Published: March 2023

PDF fiel - 55K, Provides source for all reagents used in this study
Supplementary Table 4 from Hepatocyte Growth Factor Activator Inhibitor Type 1 Is a Suppressor of Intestinal Tumorigenesis
Authors: Hoshiko Shinri , Kawaguchi Makiko , Fukushima Tsuyoshi , Haruyama Yukihiro , Yorita Kenji , Tanaka Hiroyuki , Seiki Motoharu , Inatsu Haruhiko , Kitamura Kazuo , Kataoka Hiroaki
Published: March 2023

PDF file - 36K, Spint1 deletion-induced up- and down-regulated genes involved in angiogenesis in non-neoplastic small intestine of Apc-min mice.
Supplementary Table 3 from Hepatocyte Growth Factor Activator Inhibitor Type 1 Is a Suppressor of Intestinal Tumorigenesis
Authors: Hoshiko Shinri , Kawaguchi Makiko , Fukushima Tsuyoshi , Haruyama Yukihiro , Yorita Kenji , Tanaka Hiroyuki , Seiki Motoharu , Inatsu Haruhiko , Kitamura Kazuo , Kataoka Hiroaki
Published: March 2023

PDF file - 40K, Spint1 deletion-induced mutually up-regulated genes possibly involved in angiogenesis and tumor progression.
Supplementary Table 2 from Hepatocyte Growth Factor Activator Inhibitor Type 1 Is a Suppressor of Intestinal Tumorigenesis
Authors: Hoshiko Shinri , Kawaguchi Makiko , Fukushima Tsuyoshi , Haruyama Yukihiro , Yorita Kenji , Tanaka Hiroyuki , Seiki Motoharu , Inatsu Haruhiko , Kitamura Kazuo , Kataoka Hiroaki
Published: March 2023

PDF file - 25K, Organ weights, hematocrit and hemoglobin concentration in mice.
Supplementary Table 1 from Hepatocyte Growth Factor Activator Inhibitor Type 1 Is a Suppressor of Intestinal Tumorigenesis
Authors: Hoshiko Shinri , Kawaguchi Makiko , Fukushima Tsuyoshi , Haruyama Yukihiro , Yorita Kenji , Tanaka Hiroyuki , Seiki Motoharu , Inatsu Haruhiko , Kitamura Kazuo , Kataoka Hiroaki
Published: March 2023

PDF file - 28K, Primer sequences used for RT-PCR.
Supplementary Figure 3 from Hepatocyte Growth Factor Activator Inhibitor Type 1 Is a Suppressor of Intestinal Tumorigenesis
Authors: Hoshiko Shinri , Kawaguchi Makiko , Fukushima Tsuyoshi , Haruyama Yukihiro , Yorita Kenji , Tanaka Hiroyuki , Seiki Motoharu , Inatsu Haruhiko , Kitamura Kazuo , Kataoka Hiroaki
Published: March 2023

PDF file - 158K, Enhanced angiogenesis in Spint1-deleted intestinal tumor tissue.
Supplementary Figure 2 from Hepatocyte Growth Factor Activator Inhibitor Type 1 Is a Suppressor of Intestinal Tumorigenesis
Authors: Hoshiko Shinri , Kawaguchi Makiko , Fukushima Tsuyoshi , Haruyama Yukihiro , Yorita Kenji , Tanaka Hiroyuki , Seiki Motoharu , Inatsu Haruhiko , Kitamura Kazuo , Kataoka Hiroaki
Published: March 2023

PDF file - 138K, RT-PCR and qRT-PCR analyses of gene expression.
Supplementary Figure Legends from BCR-ABL–Induced Deregulation of the IL-33/ST2 Pathway in CD34(+) Progenitors from Chronic Myeloid Leukemia Patients
Authors: Levescot Anaïs , Flamant Stéphane , Basbous Sara , Jacomet Florence , Féraud Olivier , Anne Bourgeois Elvire , Bonnet Marie-Laure , Giraud Christine , Roy Lydia , Barra Anne , Chomel Jean-Claude , Turhan Ali , Guilhot François , Girard Jean-Philippe , Gombert Jean-Marc , Herbelin André
Published: March 2023

PDF file - 89KB
Supplementary Figure 6 from Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee
Authors: Ittmann Michael , Huang Jiaoti , Radaelli Enrico , Martin Philip , Signoretti Sabina , Sullivan Ruth , Simons Brian W. , Ward Jerrold M. , Robinson Brian D. , Chu Gerald C. , Loda Massimo , Thomas George , Borowsky Alexander , Cardiff Robert D.
Published: March 2023

PDF file - 3402K, Supplementary Figure 6. Additional PTEN/AKT Pathway models.
Supplementary Figure Legend from Contrasting Hypoxic Effects on Breast Cancer Stem Cell Hierarchy Is Dependent on ER-α Status
Authors: Harrison Hannah , Rogerson Lynsey , Gregson Hannah J. , Brennan Keith R. , Clarke Robert B. , Landberg Göran
Published: March 2023

PDF file - 53K
Supplementary Figure 5 from Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee
Authors: Ittmann Michael , Huang Jiaoti , Radaelli Enrico , Martin Philip , Signoretti Sabina , Sullivan Ruth , Simons Brian W. , Ward Jerrold M. , Robinson Brian D. , Chu Gerald C. , Loda Massimo , Thomas George , Borowsky Alexander , Cardiff Robert D.
Published: March 2023

PDF file - 4441K, Supplementary Figure 5. PTEN/AKT Pathway models.
Supplementary Figure 4 from Contrasting Hypoxic Effects on Breast Cancer Stem Cell Hierarchy Is Dependent on ER-α Status
Authors: Harrison Hannah , Rogerson Lynsey , Gregson Hannah J. , Brennan Keith R. , Clarke Robert B. , Landberg Göran
Published: March 2023

PDF file - 2099K, YC1 inhibition of HIF and its effect in normoxia
Supplementary Figure 3 from Contrasting Hypoxic Effects on Breast Cancer Stem Cell Hierarchy Is Dependent on ER-α Status
Authors: Harrison Hannah , Rogerson Lynsey , Gregson Hannah J. , Brennan Keith R. , Clarke Robert B. , Landberg Göran
Published: March 2023

PDF file - 2260K, Normoxic controls, analysis of cell cycle, proliferation and viability and an extended panel of breast cancer cell lines
Supplementary Figure 1 from Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee
Authors: Ittmann Michael , Huang Jiaoti , Radaelli Enrico , Martin Philip , Signoretti Sabina , Sullivan Ruth , Simons Brian W. , Ward Jerrold M. , Robinson Brian D. , Chu Gerald C. , Loda Massimo , Thomas George , Borowsky Alexander , Cardiff Robert D.
Published: March 2023

PDF file - 9226K, Supplementary Figure 1. Differentiating primary and metastatic lung lesions in GEM mouse models.
Supplementary Methods and Figure Legend from Dynamics of Senescent Cell Formation and Retention Revealed by p14ARF Induction in the Epidermis
Authors: Tokarsky-Amiel Ronit , Azazmeh Narmen , Helman Aharon , Stein Yan , Hassan Alia , Maly Alexander , Ben-Porath Ittai
Published: March 2023

PDF file - 90K
Supplementary Figure Legend from ALX1 Induces Snail Expression to Promote Epithelial-to-Mesenchymal Transition and Invasion of Ovarian Cancer Cells
Authors: Yuan Hong , Kajiyama Hiroaki , Ito Satoko , Yoshikawa Nobuhisa , Hyodo Toshinori , Asano Eri , Hasegawa Hitoki , Maeda Masao , Shibata Kiyosumi , Hamaguchi Michinari , Kikkawa Fumitaka , Senga Takeshi
Published: March 2023

PDF file - 28K
Supplementary Figure S2 from scFv-Based “Grababody” as a General Strategy to Improve Recruitment of Immune Effector Cells to Antibody-Targeted Tumors
Authors: Cai Zheng , Fu Ting , Nagai Yasuhiro , Lam Lian , Yee Marla , Zhu Zhiqiang , Zhang Hongtao
Published: March 2023

Supplementary Figure S2 PDF file 861K, Confirmation of h4D5 and D4(508-577) interaction by immunoprecipitation
Supplementary Figure 8 from Convergence of the ZMIZ1 and NOTCH1 Pathways at C-MYC in Acute T Lymphoblastic Leukemias
Authors: Rakowski Lesley A. , Garagiola Derek D. , Li Choi M. , Decker Margaret , Caruso Sarah , Jones Morgan , Kuick Rork , Cierpicki Tomasz , Maillard Ivan , Chiang Mark Y.
Published: March 2023

PDF file - 5445K, Figure S8. C-MYC cannot substitute for ZMIZ1, but is a required effector of ZMIZ1 function.
Supplementary Information from SIRT1 and AMPK Mediate Hypoxia-Induced Resistance of Non–Small Cell Lung Cancers to Cisplatin and Doxorubicin
Authors: Shin Dong Hoon , Choi Yong-Joon , Park Jong-Wan
Published: March 2023

PDF file 66K, Supplementary Methods and Supplementary Figure Legends
Supplementary Figure 5 from SIRT1 and AMPK Mediate Hypoxia-Induced Resistance of Non–Small Cell Lung Cancers to Cisplatin and Doxorubicin
Authors: Shin Dong Hoon , Choi Yong-Joon , Park Jong-Wan
Published: March 2023

PDF file 118K, Correlation between pAMPK and SIRT1, and cell viability
Supplementary Figure 2 from Convergence of the ZMIZ1 and NOTCH1 Pathways at C-MYC in Acute T Lymphoblastic Leukemias
Authors: Rakowski Lesley A. , Garagiola Derek D. , Li Choi M. , Decker Margaret , Caruso Sarah , Jones Morgan , Kuick Rork , Cierpicki Tomasz , Maillard Ivan , Chiang Mark Y.
Published: March 2023

PDF file - 651K, Figure S2. Gene expression profiling showing expression of ZMIZ1 in human T-ALL and normal thymopoiesis.
Supplementary Figure 1 from Convergence of the ZMIZ1 and NOTCH1 Pathways at C-MYC in Acute T Lymphoblastic Leukemias
Authors: Rakowski Lesley A. , Garagiola Derek D. , Li Choi M. , Decker Margaret , Caruso Sarah , Jones Morgan , Kuick Rork , Cierpicki Tomasz , Maillard Ivan , Chiang Mark Y.
Published: March 2023

PDF file - 5445K, Figure S1. Retroviral transduction efficiency.
Supplementary Materials and Methods from Fibroblast-Specific Protein 1/S100A4–Positive Cells Prevent Carcinoma through Collagen Production and Encapsulation of Carcinogens
Authors: Zhang Jinhua , Chen Lin , Liu Xiaoman , Kammertoens Thomas , Blankenstein Thomas , Qin Zhihai
Published: March 2023

Supplementary material and methods PDF file 69K, Supplementary material and methods
Supplementary Figures 1 - 3 from Prolyl Isomerase Pin1 Acts Downstream of miR200c to Promote Cancer Stem–like Cell Traits in Breast Cancer
Authors: Luo Man-Li , Gong Chang , Chen Chun-Hau , Lee Daniel Y. , Hu Hai , Huang Pengyu , Yao Yandan , Guo Wenjun , Reinhardt Ferenc , Wulf Gerburg , Lieberman Judy , Zhou Xiao Zhen , Song Erwei , Lu Kun Ping
Published: March 2023

PDF file - 668KB, Pin1 inhibition suppresses the expansion of BCSC enriched populations (S1). Pin1 knockdown in MCF7 cells reverts EMT phenotype (S2). Pin1 promotes the expansion of BCSC-enriched populations, as well as basal/myoepithelial and luminal progenitors in primary nonmal human MECs (S3).
Supplementary Figure 3 from DKK2 Mediates Osteolysis, Invasiveness, and Metastatic Spread in Ewing Sarcoma
Authors: Hauer Kristina , Calzada-Wack Julia , Steiger Katja , Grunewald Thomas G.P. , Baumhoer Daniel , Plehm Stephanie , Buch Thorsten , da Costa Olivia Prazeres , Esposito Irene , Burdach Stefan , Richter Günther H.S.
Published: March 2023

PDF file - 5289KB, DKK2 knock-down has no effect on angiogenesis
Supplementary Figure Legends from BRCA1 Deficiency Exacerbates Estrogen-Induced DNA Damage and Genomic Instability
Authors: Savage Kienan I. , Matchett Kyle B. , Barros Eliana M. , Cooper Kevin M. , Irwin Gareth W. , Gorski Julia J. , Orr Katy S. , Vohhodina Jekaterina , Kavanagh Joy N. , Madden Angelina F. , Powell Alexander , Manti Lorenzo , McDade Simon S. , Park Ben Ho , Prise Kevin M. , McIntosh Stuart A. , Salto-Tellez Manuel , Richard Derek J. , Elliott Christopher T. , Harkin D. Paul
Published: March 2023

PDF file - 75K
Supplementary Methods and Materials and Figure Legends from Menin Epigenetically Represses Hedgehog Signaling in MEN1 Tumor Syndrome
Authors: Gurung Buddha , Feng Zijie , Iwamoto Daniel V. , Thiel Austin , Jin Guanghui , Fan Chen-Min , Ng Jessica M.Y. , Curran Tom , Hua Xianxin
Published: March 2023

PDF file - 147KB
Supplementary Material 6 from Androgen Glucuronidation: An Unexpected Target for Androgen Deprivation Therapy, with Prognosis and Diagnostic Implications
Authors: Grosse Laurent , Pâquet Sophie , Caron Patrick , Fazli Ladan , Rennie Paul S. , Bélanger Alain , Barbier Olivier
Published: March 2023

PDF file - 6791K, Supplementary material 6: Representative examples of immunoexpression obtained after incubation of prostate tissue microarrays with the anti-UGT2B15, anti-UGT2B17 or anti-vimentin antibodies: Comparison Untreated vs ADTh for 9.0 months.
Data Supplement from Chromosomal Instability Selects Gene Copy-Number Variants Encoding Core Regulators of Proliferation in ER+ Breast Cancer
Authors: Endesfelder David , Burrell Rebecca A. , Kanu Nnennaya , McGranahan Nicholas , Howell Mike , Parker Peter J. , Downward Julian , Swanton Charles , Kschischo Maik
Published: March 2023

Supplementary Figure S4. Association of genetic mutations with wGII score. The rows of the figure are ordered by the association of wGII score with gene mutations. Strong positive associations are shown on the top and strong negative associations on the bottom. The bars on the right show the negative logarithm of p-values obtained by a logistic regression model. The bars on the left of the figure show the percentage of mutations across all ER(+) patients. Columns are ordered by increasing wGII score. The various types of mutations are labelled with different colours (see legend).
Data Supplement from Chromosomal Instability Selects Gene Copy-Number Variants Encoding Core Regulators of Proliferation in ER+ Breast Cancer
Authors: Endesfelder David , Burrell Rebecca A. , Kanu Nnennaya , McGranahan Nicholas , Howell Mike , Parker Peter J. , Downward Julian , Swanton Charles , Kschischo Maik
Published: March 2023

Supplementary Table S1: Genes that impair cell viability (Z-Score < -2) in at least 3/5 cell lines (PC9 (lung), RCC4 (kidney), HCT116 (colon), MCF-10A (breast) and HT1080 (fibrosarcoma)) in RNAi screens and their Z-scores. These genes were regarded as proliferation genes. Supplementary Table S2: GO Term Enrichment for Proliferation Genes (RNAi Screens) found in Supplementary Table S1. Supplementary Table S3: Candidate core regulators prior to CONEXIC analysis. Supplementary Table S4: GO Term Enrichment of Top 30 Key Regulators. Supplementary Table S5: Top 50 GO Terms Enriched for Module Genes Belonging to Core Regulators from Table 1. P-Values were derived by Fishers Exact Test. The GO analysis for each core regulator module was done independently of the other core regulator modules. Supplementary Table S6: The amplified core regulators TPX2, AURKA, UBE2C, EXO1, MYBL2, TPT1, KIF14 and UBE2T are also members of at least one breast cancer prognostic signature.
Supplementary Figure 2 from A CD90+ Tumor-Initiating Cell Population with an Aggressive Signature and Metastatic Capacity in Esophageal Cancer
Authors: Tang Kwan Ho , Dai Yong Dong , Tong Man , Chan Yuen Piu , Kwan Pak Shing , Fu Li , Qin Yan Ru , Tsao Sai Wah , Lung Hong Lok , Lung Maria L. , Tong Daniel K. , Law Simon , Chan Kwok Wah , Ma Stephanie , Guan Xin Yuan
Published: March 2023

PDF file - 1414K, Supplemental Figure 2. CD90, CD44 and p75NTR / CD271 expression in matched non-tumor (N) and primary ESCC (T) (n = 33) as detected by real-time qPCR.
Supplementary Figure Legends from Differential Contributions of STAT5A and STAT5B to Stress Protection and Tyrosine Kinase Inhibitor Resistance of Chronic Myeloid Leukemia Stem/Progenitor Cells
Authors: Casetti Luana , Martin-Lannerée Séverine , Najjar Imen , Plo Isabelle , Augé Sylvie , Roy Lydia , Chomel Jean-Claude , Lauret Evelyne , Turhan Ali G. , Dusanter-Fourt Isabelle
Published: March 2023

PDF file - 32K
Supplementary Video 3 from Senescent Fibroblasts in Melanoma Initiation and Progression: An Integrated Theoretical, Experimental, and Clinical Approach
Authors: Kim Eunjung , Rebecca Vito , Fedorenko Inna V. , Messina Jane L. , Mathew Rahel , Maria-Engler Silvya S. , Basanta David , Smalley Keiran S.M. , Anderson Alexander R.A.
Published: March 2023

MOV file - 9113K, This video shows the spatio-temporal evolution of vSkin that produced Figure 4B (biochemical perturbation).
Supplementary Figure 6 from Mature Cytotoxic CD56bright/CD16+ Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Authors: Messaoudene Meriem , Fregni Giulia , Fourmentraux-Neves Emmanuelle , Chanal Johan , Maubec Eve , Mazouz-Dorval Sarra , Couturaud Benoit , Girod Angelique , Sastre-Garau Xavier , Albert Sebastien , Guédon Charles , Deschamps Lydia , Mitilian Delphine , Cremer Isabelle , Jacquelot Nicolas , Rusakiewicz Sylvie , Zitvogel Laurence , Avril Marie-Francoise , Caignard Anne
Published: March 2023

PDF file - 359K, NK cell mediated lysis determined by dynamic measure of cell index of adherent melanoma targets.
Supplementary Figure 4 from Mature Cytotoxic CD56bright/CD16+ Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
Authors: Messaoudene Meriem , Fregni Giulia , Fourmentraux-Neves Emmanuelle , Chanal Johan , Maubec Eve , Mazouz-Dorval Sarra , Couturaud Benoit , Girod Angelique , Sastre-Garau Xavier , Albert Sebastien , Guédon Charles , Deschamps Lydia , Mitilian Delphine , Cremer Isabelle , Jacquelot Nicolas , Rusakiewicz Sylvie , Zitvogel Laurence , Avril Marie-Francoise , Caignard Anne
Published: March 2023

PDF file - 437K, Characterization of the M-LN CD56bright CD16+ and CD16- NK cell subsets.
Supplementary Figure 3 from Transient Antiangiogenic Treatment Improves Delivery of Cytotoxic Compounds and Therapeutic Outcome in Lung Cancer
Authors: Chatterjee Sampurna , Wieczorek Caroline , Schöttle Jakob , Siobal Maike , Hinze Yvonne , Franz Thomas , Florin Alexandra , Adamczak Joanna , Heukamp Lukas C. , Neumaier Bernd , Ullrich Roland T.
Published: March 2023

PDF file - 665KB, Imaging of tumor cell proliferation using 18FFLT PET in H1975 tumors.
Supplementary Video 7 from Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues
Authors: Varone Antonio , Xylas Joanna , Quinn Kyle P. , Pouli Dimitra , Sridharan Gautham , McLaughlin-Drubin Margaret E. , Alonzo Carlo , Lee Kyongbum , Münger Karl , Georgakoudi Irene
Published: March 2023

AVI file - 1119KB, Representative endogenous TPEF OPTICAL STACK E6E7 EETE.
Supplementary Video 4 from Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues
Authors: Varone Antonio , Xylas Joanna , Quinn Kyle P. , Pouli Dimitra , Sridharan Gautham , McLaughlin-Drubin Margaret E. , Alonzo Carlo , Lee Kyongbum , Münger Karl , Georgakoudi Irene
Published: March 2023

AVI file - 1230KB, Representative 3D RENDERING HKcDR EETE.
Supplementary Figure 2 from Mixed Lineage Kinase MLK4 Is Activated in Colorectal Cancers Where It Synergistically Cooperates with Activated RAS Signaling in Driving Tumorigenesis
Authors: Martini Miriam , Russo Mariangela , Lamba Simona , Vitiello Elisa , Crowley Emily Hannah , Sassi Francesco , Romanelli Davide , Frattini Milo , Marchetti Antonio , Bardelli Alberto
Published: March 2023

PDF file - 246K, A) Proliferation rates of HCT116 parental and MLK4 -/- cancer cells (two independent clones).*p value < 0.05; **p value < 0.01; error bars represent s.d; FC, fold change. B) Expression levels of the MLK4 protein were assessed by western blotting in control (ctrl) and MLK4 knock down LoVo cells (upper panel). C) Proliferation rates of ctrl and MLK4 knock down LoVo cells grown in plastic . *p value < 0.05; **p value < 0.01; error bars represent s.d; FC, fold change. D) Proliferation rates of Ctrl and MLK4 knock down LoVo cells grown in low adherence conditions. *p value < 0.05; **p value < 0.01; error bars represent s.d; FC, fold change. E) Anchorage-independent growth (soft agar) assay performed on control and MLK4 knock down LoVo cells. ***p value < 0.001; error bars represent s.d.
Supplementary Table 2 from Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients
Authors: Tel Jurjen , Aarntzen Erik H.J.G. , Baba Tetsuro , Schreibelt Gerty , Schulte Barbara M. , Benitez-Ribas Daniel , Boerman Otto C. , Croockewit Sandra , Oyen Wim J.G. , van Rossum Michelle , Winkels Gregor , Coulie Pierre G. , Punt Cornelis J.A. , Figdor Carl G. , de Vries I. Jolanda M.
Published: March 2023

Supplementary Table 2 PDF file - 30K, Patient characteristics and historical controls
Supplementary Figure 5 from TGF-β Mediates Homing of Bone Marrow–Derived Human Mesenchymal Stem Cells to Glioma Stem Cells
Authors: Shinojima Naoki , Hossain Anwar , Takezaki Tatsuya , Fueyo Juan , Gumin Joy , Gao Feng , Nwajei Felix , Marini Frank C. , Andreeff Michael , Kuratsu Jun-Ichi , Lang Frederick F.
Published: March 2023

PDF file - 2556K, TGFβ levels do not alter tumor vascularity or tumor size.
Supplementary Figure 1 from FOXC2 Expression Links Epithelial–Mesenchymal Transition and Stem Cell Properties in Breast Cancer
Authors: Hollier Brett G. , Tinnirello Agata A. , Werden Steven J. , Evans Kurt W. , Taube Joseph H. , Sarkar Tapasree Roy , Sphyris Nathalie , Shariati Maryam , Kumar Sreedevi V. , Battula Venkata L. , Herschkowitz Jason I. , Guerra Rudy , Chang Jeffrey T. , Miura Naoyuki , Rosen Jeffrey M. , Mani Sendurai A.
Published: March 2023

Supplementary Figure 1 PDF File - 22K, FOXC2 does not regulate the expression of other EMT factors. Quantification of EMT marker mRNA expression by quantitative real-time PCR analysis. Data is represented as the expression of EMT markers in HMLER-FOXC2 (FOXC2) cells relative to HMLER control cells GAPDH was used as an internal normalization control. Columns indicate the mean (n = 3); error bars indicate SEM.
Supplementary Figure 5 from Myeloid-Specific Expression of Ron Receptor Kinase Promotes Prostate Tumor Growth
Authors: Gurusamy Devikala , Gray Jerilyn K. , Pathrose Peterson , Kulkarni Rishikesh M. , Finkleman Fred D. , Waltz Susan E.
Published: March 2023

PDF file - 50K, Microvessel staining in tumors isolated from TKf/f and TKf/f LysMcre+ mice. For Review and Publication Both.
Supplementary Figure 1 from Myeloid-Specific Expression of Ron Receptor Kinase Promotes Prostate Tumor Growth
Authors: Gurusamy Devikala , Gray Jerilyn K. , Pathrose Peterson , Kulkarni Rishikesh M. , Finkleman Fred D. , Waltz Susan E.
Published: March 2023

PDF file - 194K, Loss of Ron increases the migratory potential of macrophages in vivo and in vitro. For Review and Publication Both.
Supplementary Figure 5 from MYC Regulation of CHK1 and CHK2 Promotes Radioresistance in a Stem Cell-like Population of Nasopharyngeal Carcinoma Cells
Authors: Wang Wen-Jun , Wu Si-Pei , Liu Jia-Bin , Shi Yong-Sheng , Huang Xue , Zhang Qian-Bing , Yao Kai-Tai
Published: March 2023

PDF file - 3834K, A, Tumors from xenografts after treatment for 55 days. B, Representative IHC staining of tumor samples for Ki67 and Brdu after indicated treatments
Supplementary Figure 3 from PTEN Loss Mitigates the Response of Medulloblastoma to Hedgehog Pathway Inhibition
Authors: Metcalfe Ciara , Alicke Bruno , Crow Ailey , Lamoureux Marlea , Dijkgraaf Gerrit J.P. , Peale Franklin , Gould Stephen E. , de Sauvage Frederic J.
Published: March 2023

PDF file - 286K,Proliferation is suppressed in PPM tumors. Phosphorylation of histone H3 (pH3) is tightly correlated with chromosome condensation during mitosis. PM tumors have a high frequency of pH3 positive cells, while in PPM and PPwt/loxpM tumors, pH3 positive cells tend to occur in restricted regions.
Supplementary Figure 2 from PTEN Loss Mitigates the Response of Medulloblastoma to Hedgehog Pathway Inhibition
Authors: Metcalfe Ciara , Alicke Bruno , Crow Ailey , Lamoureux Marlea , Dijkgraaf Gerrit J.P. , Peale Franklin , Gould Stephen E. , de Sauvage Frederic J.
Published: March 2023

PDF file - 1233K, Loss of PTEN in Math1-expressing granule neuronal precursor cells results in ectopic positioning of enlarged NeuN-expressing cells.
Supplementary Figure 1 from Automated Tracking of Nanoparticle-labeled Melanoma Cells Improves the Predictive Power of a Brain Metastasis Model
Authors: Sundstrøm Terje , Daphu Inderjit , Wendelbo Ingvild , Hodneland Erlend , Lundervold Arvid , Immervoll Heike , Skaftnesmo Kai Ove , Babic Michal , Jendelova Pavla , Sykova Eva , Lund-Johansen Morten , Bjerkvig Rolf , Thorsen Frits
Published: March 2023

PDF file - 355K, From human melanoma brain metastases to transfected cell line
Supplementary Figure Legend from Ex Vivo Activation of CD56+ Immune Cells That Eradicate Neuroblastoma
Authors: Rujkijyanont Piya , Chan Wing Keung , Eldridge Paul W. , Lockey Timothy , Holladay Martha , Rooney Barbara , Davidoff Andrew M. , Leung Wing , Vong Queenie
Published: March 2023

PDF file - 74K, Legend for Supplementary Figure 1
Supplementary Methods from Cholesterol Loading and Ultrastable Protein Interactions Determine the Level of Tumor Marker Required for Optimal Isolation of Cancer Cells
Authors: Jain Jayati , Veggiani Gianluca , Howarth Mark
Published: March 2023

Supplementary Methods PDF file - 192K,Contains methods for cloning and expression of proteins, flow cytometry, biotinylation, microscopy, statistics and selected magnetic isolation procedures
Supplementary Figure 5 from Therapeutic PD-1 Pathway Blockade Augments with Other Modalities of Immunotherapy T-Cell Function to Prevent Immune Decline in Ovarian Cancer
Authors: Duraiswamy Jaikumar , Freeman Gordon J. , Coukos George
Published: March 2023

PDF file, 41K, Synergistic effect of PD-1 or PD-L1 blockade with vaccination and co-stimulation (TLR 9 ligand) on ovarian ID8 tumor rejection.
Supplementary Figures S1-S9 from Cholesterol Loading and Ultrastable Protein Interactions Determine the Level of Tumor Marker Required for Optimal Isolation of Cancer Cells
Authors: Jain Jayati , Veggiani Gianluca , Howarth Mark
Published: March 2023

Supplementary Figures S1-S9 PDF file 2507K, Testing Fab monobiotinylation (S1); Relationship between Fab0.11 antibody concentration and number of antibodies bound per cell (S2); Cell recovery sensitivity was enhanced by twin biotin tags on the antibody (S3); Chemically biotinylated antibody also gave efficient cell isolation (S4); Effect of cholesterol on surface staining for HER2 (S5); Cholesterol loading and direct bead linkage enhanced the recovery even with lower affinity antibody (S6); Effect of individual changes on recovery of cells varying in HER2 expression (S7); Cholesterol loading and direct bead linkage enhanced isolation of cells expressing low levels of EpCAM (S8); Specificity of recovery of cancer cell-lines from blood (S9)
Supplementary Figures 1 - 7 from HTLV-1 bZIP Factor Suppresses Apoptosis by Attenuating the Function of FoxO3a and Altering Its Localization
Authors: Tanaka-Nakanishi Azusa , Yasunaga Jun-ichirou , Takai Ken , Matsuoka Masao
Published: March 2023

PDF file - 373K, HBZ also inhibited Doxorubicin-induced cell death (S1); FoxO3a transcript in shRNA transfectant of Jurkat was quantified by real-time PCR (S2); Expression of the TP73 gene mRNA (S3); Comparison of the HBZ mRNA expression in Jurkat-HBZ, CEM-HBZ and ATL cell lines (S4); The results of GSE33615 affymetrix microarray data in Bim and FasL genes, which were normalized to GAPDH (S5); DNA methylation in the promoter region of the Bim gene (S6); Epigenetic status of the promoter1 of the Bim gene (S7).
Supplementary Figure 3 from NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis
Authors: Qin Li , Wu Ye-Lin , Toneff Michael J. , Li Dabing , Liao Lan , Gao Xiuhua , Bane Fiona T. , Tien Jean C.-Y. , Xu Yixiang , Feng Zhen , Yang Zhihui , Xu Yan , Theissen Sarah M. , Li Yi , Young Leonie , Xu Jianming
Published: March 2023

PDF file - 72KB, Positive controls for transfection assays.
Supplementary Figure Legend from HTLV-1 bZIP Factor Suppresses Apoptosis by Attenuating the Function of FoxO3a and Altering Its Localization
Authors: Tanaka-Nakanishi Azusa , Yasunaga Jun-ichirou , Takai Ken , Matsuoka Masao
Published: March 2023

PDF file - 75K
Supplementary Table 9 from Global Transcriptome Analysis of Formalin-Fixed Prostate Cancer Specimens Identifies Biomarkers of Disease Recurrence
Authors: Long Qi , Xu Jianpeng , Osunkoya Adeboye O. , Sannigrahi Soma , Johnson Brent A. , Zhou Wei , Gillespie Theresa , Park Jong Y. , Nam Robert K. , Sugar Linda , Stanimirovic Aleksandra , Seth Arun K. , Petros John A. , Moreno Carlos S.
Published: March 2023

XLSX file - 33K, Set of 304 genes differentially expressed between Gleason 3+4 pattern and Gleason 4+3 pattern patients based on DEseq analysis (p < 0.05).
Supplementary Methods , Figure Legends 1-6 from CD40-Mediated Activation of Chronic Lymphocytic Leukemia Cells Promotes Their CD44-Dependent Adhesion to Hyaluronan and Restricts CCL21-Induced Motility
Authors: Girbl Tamara , Hinterseer Elisabeth , Grössinger Eva Melanie , Asslaber Daniela , Oberascher Karin , Weiss Lukas , Hauser-Kronberger Cornelia , Neureiter Daniel , Kerschbaum Hubert , Naor David , Alon Ronen , Greil Richard , Hartmann Tanja Nicole
Published: March 2023

PDF file - 105K
Supplementary Figure 4 from Global Transcriptome Analysis of Formalin-Fixed Prostate Cancer Specimens Identifies Biomarkers of Disease Recurrence
Authors: Long Qi , Xu Jianpeng , Osunkoya Adeboye O. , Sannigrahi Soma , Johnson Brent A. , Zhou Wei , Gillespie Theresa , Park Jong Y. , Nam Robert K. , Sugar Linda , Stanimirovic Aleksandra , Seth Arun K. , Petros John A. , Moreno Carlos S.
Published: March 2023

PDF file - 1288K, Distribution of genes with FPKM > 1. Genes are binned into deciles of percentage of samples in which the FPKM was > 1. Thus for a gene with FPKM > 1 in 65% of samples, the gene would be included in 60-70% bin. Y-axis is the number of genes in each decile.
Supplementary Figure 3 from Global Transcriptome Analysis of Formalin-Fixed Prostate Cancer Specimens Identifies Biomarkers of Disease Recurrence
Authors: Long Qi , Xu Jianpeng , Osunkoya Adeboye O. , Sannigrahi Soma , Johnson Brent A. , Zhou Wei , Gillespie Theresa , Park Jong Y. , Nam Robert K. , Sugar Linda , Stanimirovic Aleksandra , Seth Arun K. , Petros John A. , Moreno Carlos S.
Published: March 2023

PDF file - 1172K, Log2 FPKM+1 values are plotted for the six samples that were sequenced in duplicate. Plots include data for the 5265 detected genes used in the biomarker analysis. R-squared values are indicated for the best fit linear curve for each duplicate sample.
Supplementary Figure 1 from Global Transcriptome Analysis of Formalin-Fixed Prostate Cancer Specimens Identifies Biomarkers of Disease Recurrence
Authors: Long Qi , Xu Jianpeng , Osunkoya Adeboye O. , Sannigrahi Soma , Johnson Brent A. , Zhou Wei , Gillespie Theresa , Park Jong Y. , Nam Robert K. , Sugar Linda , Stanimirovic Aleksandra , Seth Arun K. , Petros John A. , Moreno Carlos S.
Published: March 2023

PDF file - 2194K, RNAseq data from the IGFBP3 gene in the IGV browser for representative FFPE samples (top four tracks) and TCGA prostate samples (bottom three tracks) showing intronic reads.
Supplementary Materials, Figures 1 - 2, Table 1 from The RAD51-Stimulatory Compound RS-1 Can Exploit the RAD51 Overexpression That Exists in Cancer Cells and Tumors
Authors: Mason Jennifer M. , Logan Hillary L. , Budke Brian , Wu Megan , Pawlowski Michal , Weichselbaum Ralph R. , Kozikowski Alan P. , Bishop Douglas K. , Connell Philip P.
Published: March 2023

PDF file - 403KB, Supplemental Figure 1. Quantifications of western blots. Supplemental Figure 2. Knockdown of RAD51 in PC3 does not protect cells from the toxicity of ionizing radiation. Supplemental Table 1. Quantifications of statistical significance are displayed for the RS-1 toxicity data that are displayed in Figure 2. Supplemental Methods. Chemical synthesis of compounds.
Supplementary Methods from Selection of Personalized Patient Therapy through the Use of Knowledge-Based Computational Models That Identify Tumor-Driving Signal Transduction Pathways
Authors: Verhaegh Wim , van Ooijen Henk , Inda Márcia A. , Hatzis Pantelis , Versteeg Rogier , Smid Marcel , Martens John , Foekens John , van de Wiel Paul , Clevers Hans , van de Stolpe Anja
Published: March 2023

PDF file - 174KB, Details of the modeling approach, selected genes and probesets, and additional results. Also includes supplementary references.
Supplementary Figure 1 from Transient Induction of ING4 by Myc Drives Prostate Epithelial Cell Differentiation and Its Disruption Drives Prostate Tumorigenesis
Authors: Berger Penny L. , Frank Sander B. , Schulz Veronique V. , Nollet Eric A. , Edick Mathew J. , Holly Brittany , Chang Ting-Tung A. , Hostetter Galen , Kim Suwon , Miranti Cindy K.
Published: March 2023

PDF file - 343KB, Marker Validation of Differentiated Cells.
Supplementary Table 1 from Combination Therapy Targeting the Chk1 and Wee1 Kinases Shows Therapeutic Efficacy in Neuroblastoma
Authors: Russell Mike R. , Levin Kirill , Rader JulieAnn , Belcastro Lili , Li Yimei , Martinez Daniel , Pawel Bruce , Shumway Stuart D. , Maris John M. , Cole Kristina A.
Published: March 2023

PDF file - 42K, Therapies targeting Chk1/Wee1 in combination with chemotherapy demonstrates synergy in most neuroblastoma cells. Ten neuroblastoma cell lines were tested for synergistic interactions between MK-1775 or MK-8776 in combination with either SN-38 (irinotecan) or gemcitabine. Combination indices were determined by increasing concentrations of both drug simultaneously (based on multiples of each drugs individual IC50), utilizing the Chou-Talalay method. The majority of neuroblastoma lines demonstrated synergy (denoted by a CI value < 0.7) in combination with chemotherapy, and particularly in the MK-1775 + MK-8776 combination group
Supplementary Figure Legends 1-4, Table Legend 1 from Combination Therapy Targeting the Chk1 and Wee1 Kinases Shows Therapeutic Efficacy in Neuroblastoma
Authors: Russell Mike R. , Levin Kirill , Rader JulieAnn , Belcastro Lili , Li Yimei , Martinez Daniel , Pawel Bruce , Shumway Stuart D. , Maris John M. , Cole Kristina A.
Published: March 2023

PDF file - 55K
upplementary Data Legend from Ex Vivo Expansion of Highly Cytotoxic Human NK Cells by Cocultivation with Irradiated Tumor Cells for Adoptive Immunotherapy
Authors: Lim Seon Ah , Kim Tae-Jin , Lee Jung Eun , Sonn Chung Hee , Kim Kwanghee , Kim Jiyoung , Choi Jong Gwon , Choi Il-Kyu , Yun Chae-Ok , Kim Jae-Hong , Yee Cassian , Kumar Vinay , Lee Kyung-Mi
Published: March 2023

upplementary Data Legend PDF file - 94K, Supplementary data legend
Supplementary Figure S6 from Ex Vivo Expansion of Highly Cytotoxic Human NK Cells by Cocultivation with Irradiated Tumor Cells for Adoptive Immunotherapy
Authors: Lim Seon Ah , Kim Tae-Jin , Lee Jung Eun , Sonn Chung Hee , Kim Kwanghee , Kim Jiyoung , Choi Jong Gwon , Choi Il-Kyu , Yun Chae-Ok , Kim Jae-Hong , Yee Cassian , Kumar Vinay , Lee Kyung-Mi
Published: March 2023

Supplementary Figure S6 PDF file - 23K, KL-1-mediated NK cell expansion from PBMC of healthy and patient donors was performed as described in Materials and Methods section of manuscript. PBMCs was co-cultivated with irradiated KL-1 at a ratio of 1:1 and supplemented with IL-2 500 U/ml every 3 days. On Day 14, the absolute number of NK cells was calculated by multiplying the total viable number of cells, as determined by manual counting with a hemacytometer, by the percentage of CD56+CD3- cells as determined by flow cytometry. Results are displayed as a scattergram. The mean number of NK cells expanded is shown as straight line. Although there is a trend towards increased expansion among healthy donors compared to patient donors, this linearity was not preserved and no statistically significant difference is noted between healthy donors and patients with cancer
Supplementary Figure 4 from FGF-2 Disrupts Mitotic Stability in Prostate Cancer through the Intracellular Trafficking Protein CEP57
Authors: Cuevas Rolando , Korzeniewski Nina , Tolstov Yanis , Hohenfellner Markus , Duensing Stefan
Published: March 2023

PDF file - 311K, CEP57 increases the abundance of acetylated α-tubulin.
Supplementary Figure 1 from Phosphorylation of Ribosomal Protein S6 Attenuates DNA Damage and Tumor Suppression during Development of Pancreatic Cancer
Authors: Khalaileh Abed , Dreazen Avigail , Khatib Areej , Apel Roy , Swisa Avital , Kidess-Bassir Norma , Maitra Anirban , Meyuhas Oded , Dor Yuval , Zamir Gideon
Published: March 2023

PDF file - 3639K, Representative images of pancreatic lesions in wild type mice implanted with DMBA, or in Pdx1-Cre; LSL-Kras G12D mice.
Supplementary Movie S1 from Arkadia Regulates Tumor Metastasis by Modulation of the TGF-β Pathway
Authors: Briones-Orta Marco A. , Levy Laurence , Madsen Chris D. , Das Debipriya , Erker Yigit , Sahai Erik , Hill Caroline S.
Published: March 2023

Supplementary Movie S1 AVI file - 1075K, GFP-labeled parental MDA-MB-231 cells were seeded on top of a layer of HUVEC cells, and images were acquired every 5 min using a Plan apochromat 20x 0.8 objective on a Zeiss LSM 780 confocal microscope. The movie was created using Imaris software (Bitplane)
Supplementary Figure Legends from Cancer-Associated Fibroblasts Expressing CXCL14 Rely upon NOS1-Derived Nitric Oxide Signaling for Their Tumor-Supporting Properties
Authors: Augsten Martin , Sjöberg Elin , Frings Oliver , Vorrink Sabine U. , Frijhoff Jeroen , Olsson Eleonor , Borg Åke , Östman Arne
Published: March 2023

PDF file - 104KB
Supplementary Figure 6 from Cancer-Associated Fibroblasts Expressing CXCL14 Rely upon NOS1-Derived Nitric Oxide Signaling for Their Tumor-Supporting Properties
Authors: Augsten Martin , Sjöberg Elin , Frings Oliver , Vorrink Sabine U. , Frijhoff Jeroen , Olsson Eleonor , Borg Åke , Östman Arne
Published: March 2023

PDF file - 71KB, Expression of CAF marker by engineered fibroblasts.
Supplementary Table 1 from CHD1 Is a 5q21 Tumor Suppressor Required for ERG Rearrangement in Prostate Cancer
Authors: Burkhardt Lia , Fuchs Sarah , Krohn Antje , Masser Sawinee , Mader Malte , Kluth Martina , Bachmann Frederik , Huland Hartwig , Steuber Thomas , Graefen Markus , Schlomm Thorsten , Minner Sarah , Sauter Guido , Sirma Hüseyin , Simon Ronald
Published: March 2023

PDF file - 101K, GISTIC analysis of genomic rearrangements (cytoband) significantly associated with 5q21 deletion. The cytobands, significance (q value) and peak boundaries are indicated.
Supplementary Materials and Methods from β-Catenin Activation in a Novel Liver Progenitor Cell Type Is Sufficient to Cause Hepatocellular Carcinoma and Hepatoblastoma
Authors: Mokkapati Sharada , Niopek Katharina , Huang Le , Cunniff Kegan J. , Ruteshouser E. Cristy , deCaestecker Mark , Finegold Milton J. , Huff Vicki
Published: March 2023

PDF file - 90KB
Supplementary Figure 2 from β-Catenin Activation in a Novel Liver Progenitor Cell Type Is Sufficient to Cause Hepatocellular Carcinoma and Hepatoblastoma
Authors: Mokkapati Sharada , Niopek Katharina , Huang Le , Cunniff Kegan J. , Ruteshouser E. Cristy , deCaestecker Mark , Finegold Milton J. , Huff Vicki
Published: March 2023

PDF file - 105KB, FACS analysis of fetal cell suspensions for hepatic stem/progenitor markers.
Supplementary Methods from Enhancement of Antitumor Immunity in Lung Cancer by Targeting Myeloid-Derived Suppressor Cell Pathways
Authors: Sawant Anandi , Schafer Cara C. , Jin Tong Huan , Zmijewski Jaroslaw , Tse Hubert M. , Roth Justin , Sun Zhihuan , Siegal Gene P. , Thannickal Victor J. , Grant Stefan C. , Ponnazhagan Selvarangan , Deshane Jessy S.
Published: March 2023

PDF file - 31K, Description of additional methods and procedures used in the study.
Supplementary Figure Legend from Taccalonolide Binding to Tubulin Imparts Microtubule Stability and Potent In Vivo Activity
Authors: Risinger A.L. , Li J. , Bennett M.J. , Rohena C.C. , Peng J. , Schriemer D.C. , Mooberry S.L.
Published: March 2023

PDF file - 62K
Supplementary Figure 4 from Taccalonolide Binding to Tubulin Imparts Microtubule Stability and Potent In Vivo Activity
Authors: Risinger A.L. , Li J. , Bennett M.J. , Rohena C.C. , Peng J. , Schriemer D.C. , Mooberry S.L.
Published: March 2023

PDF file - 218K, High magnification electron micrographs (20,000x and 50,000x) of microtubules formed in the presence of 2 mg/ml tubulin with 10 microM AJ, PTX or LAU after repolymerization at 37 degrees C for 30 min after chilling.
Supplementary Figure 1 from Taccalonolide Binding to Tubulin Imparts Microtubule Stability and Potent In Vivo Activity
Authors: Risinger A.L. , Li J. , Bennett M.J. , Rohena C.C. , Peng J. , Schriemer D.C. , Mooberry S.L.
Published: March 2023

PDF file - 225K, High magnification electron micrographs (20,000x and 50,000x) of microtubules formed in the presence of 2 mg/ml tubulin with 10 microM AJ, PTX or LAU 60 min after tubulin reactions were warmed to 37 degrees C.
Supplementary Methods from Dormant Cancer Cells Contribute to Residual Disease in a Model of Reversible Pancreatic Cancer
Authors: Lin Wan-chi , Rajbhandari Nirakar , Liu Chengbao , Sakamoto Kazuhito , Zhang Qian , Triplett Aleata A. , Batra Surinder K. , Opavsky Rene , Felsher Dean W. , DiMaio Dominick J. , Hollingsworth Michael A. , Morris John P. , Hebrok Matthias , Witkiewicz Agnieszka K. , Brody Jonathan R. , Rui Hallgeir , Wagner Kay-Uwe
Published: March 2023

PDF file - 28K, Supplemental Methods describing the genetic background of genetically engineered mice and methodology to quantify the expression of Myc in human pancreatic cancer.
Supplementary Figure Legend from Dormant Cancer Cells Contribute to Residual Disease in a Model of Reversible Pancreatic Cancer
Authors: Lin Wan-chi , Rajbhandari Nirakar , Liu Chengbao , Sakamoto Kazuhito , Zhang Qian , Triplett Aleata A. , Batra Surinder K. , Opavsky Rene , Felsher Dean W. , DiMaio Dominick J. , Hollingsworth Michael A. , Morris John P. , Hebrok Matthias , Witkiewicz Agnieszka K. , Brody Jonathan R. , Rui Hallgeir , Wagner Kay-Uwe
Published: March 2023

PDF file - 40K
Supplementary Figure 5 from Cell Surface Receptor FPR2 Promotes Antitumor Host Defense by Limiting M2 Polarization of Macrophages
Authors: Liu Ying , Chen Keqiang , Wang Chunyan , Gong Wanghua , Yoshimura Teizo , Liu Mingyong , Wang Ji Ming
Published: March 2023

PDF file - 70K, Production of chemokines by freshly isolated tumor cells
Supplementary Figure 3 from An Essential Requirement for the SCAP/SREBP Signaling Axis to Protect Cancer Cells from Lipotoxicity
Authors: Williams Kevin J. , Argus Joseph P. , Zhu Yue , Wilks Moses Q. , Marbois Beth N. , York Autumn G. , Kidani Yoko , Pourzia Alexandra L. , Akhavan David , Lisiero Dominique N. , Komisopoulou Evangelia , Henkin Amy H. , Soto Horacio , Chamberlain Brian T. , Vergnes Laurent , Jung Michael E. , Torres Jorge Z. , Liau Linda M. , Christofk Heather R. , Prins Robert M. , Mischel Paul S. , Reue Karen , Graeber Thomas G. , Bensinger Steven J.
Published: March 2023

PDF File - 52K, Cholesterol content is unchanged in SREBP loss-of-function cells.
Supplementary Figure 2 from An Essential Requirement for the SCAP/SREBP Signaling Axis to Protect Cancer Cells from Lipotoxicity
Authors: Williams Kevin J. , Argus Joseph P. , Zhu Yue , Wilks Moses Q. , Marbois Beth N. , York Autumn G. , Kidani Yoko , Pourzia Alexandra L. , Akhavan David , Lisiero Dominique N. , Komisopoulou Evangelia , Henkin Amy H. , Soto Horacio , Chamberlain Brian T. , Vergnes Laurent , Jung Michael E. , Torres Jorge Z. , Liau Linda M. , Christofk Heather R. , Prins Robert M. , Mischel Paul S. , Reue Karen , Graeber Thomas G. , Bensinger Steven J.
Published: March 2023

PDF File - 155K, The lipogenic program and growth of glioma cells is SCAP sensitive.
Supplementary Figure 2 from Cell Surface Receptor FPR2 Promotes Antitumor Host Defense by Limiting M2 Polarization of Macrophages
Authors: Liu Ying , Chen Keqiang , Wang Chunyan , Gong Wanghua , Yoshimura Teizo , Liu Mingyong , Wang Ji Ming
Published: March 2023

PDF file - 90K, Anti-CCL2 antibody specifically blocked CCL2- and LLC Sup-induced chemotaxis of WT mouse macrophages
Supplementary Figure 2 from Chemotherapy Acts as an Adjuvant to Convert the Tumor Microenvironment into a Highly Permissive State for Vaccination-Induced Antitumor Immunity
Authors: Kang Tae Heung , Mao Chih-Ping , Lee Sung Yong , Chen Alexander , Lee Ji-Hyun , Kim Tae Woo , Alvarez Ronald D. , Roden Richard B.S. , Pardoll Drew , Hung Chien-Fu , Wu T.-C.
Published: March 2023

PDF file - 656K, Effect of chemotherapy on HMGB1 secretion
Supplementary Figures 1 - 6, Tables 1 - 7 from Biallelic DICER1 Mutations in Sporadic Pleuropulmonary Blastoma
Authors: Seki Masafumi , Yoshida Kenichi , Shiraishi Yuichi , Shimamura Teppei , Sato Yusuke , Nishimura Riki , Okuno Yusuke , Chiba Kenichi , Tanaka Hiroko , Kato Keisuke , Kato Motohiro , Hanada Ryoji , Nomura Yuko , Park Myoung-Ja , Ishida Toshiaki , Oka Akira , Igarashi Takashi , Miyano Satoru , Hayashi Yasuhide , Ogawa Seishi , Takita Junko
Published: March 2023

PDF file - 1805KB, Supplementary Table S1. List of primers used for validation of somatic mutations detected by whole-exome sequencing. Supplementary Table S2. Primers for DICER1 sequencing of all coding exons. Supplementary Table S3. Primers for DICER1 sequencing of all coding exons in paraffin embedded samples. Supplementary Table S4. Primers for TP53, UBA2, PDCD2L, CTNNB1, and GPR182. Supplementary Table S5. List of mutated genes detected by whole-exome sequencing. Supplementary Table S6. Allele frequency of DICER1 mutations in cases with unknown somatic status. Supplementary Table S7. Recurrent mutations detected by whole-exome sequencing. Supplementary Figure S1. Analyzing processes using Genomon. Supplementary Figure S2. Mean coverage of whole-exome sequencing in primary tumor, relapse tumor, and control samples. Supplementary Figure S3. Mean coverage of whole exome sequencing with GC contents in primary tumor, relapse tumor and control samples. Supplementary Figure S4. Detected mutations of DICER1 by Sanger sequencing. Supplementary Figure S5. Distribution of genetic lesions with 14 samples in PPB cases. Supplementary Figure S6. Common amplification lesion at 19q13.11.
Supplementary Tables 1 and 2 from Mechanisms Promoting Escape from Mitotic Stress–Induced Tumor Cell Death
Authors: Sinnott Rebecca , Winters Leah , Larson Brittany , Mytsa Daniela , Taus Patrick , Cappell Kathryn M. , Whitehurst Angelique W.
Published: March 2023

XLSX - 4269K, Supplementary Table 1 lists viability scores from the pan-genomic siRNA screen. Supplementary Table 2 lists the high interest chemosensitizers and indicates those siRNA pools selected for secondary screening analysis.
Supplementary Figure 5 from Genetic and Pharmacologic Inhibition of mTORC1 Promotes EMT by a TGF-β–Independent Mechanism
Authors: Mikaelian Ivan , Malek Mouhannad , Gadet Rudy , Viallet Jean , Garcia Amandine , Girard-Gagnepain Anaïs , Hesling Cédric , Gillet Germain , Gonzalo Philippe , Rimokh Ruth , Billaud Marc
Published: March 2023

PDF file - 741K, Supplementary Figure 5: Silencing of mTOR and RPTOR activates ZEB1 mRNA expression in various cell lines.
Supplementary Figures 1 - 6 from Aire Deficiency Promotes TRP-1–Specific Immune Rejection of Melanoma
Authors: Zhu Meng-Lei , Nagavalli Anil , Su Maureen A.
Published: March 2023

PDF file - 2957K, Supplementary Figure 1. Increased autoantibodies to B16 melanoma extract and decreased B16 melanoma growth in Aire-deficient mice. Supplementary Figure 2. Increased frequency of activated/memory T cells in Aire-deficient mice inoculated with B16 melanoma cells. Supplementary Figure 3. No change in T cell activation and cytokine secretion in AireGW/+ mice spleen and lymph nodes. Supplementary Figure 4. Reconstitution of T cells in B6 Nude mice transplanted with either WT or AireGW/+ thymi. Supplementary Figure 5. Defective negative selection of TRP-1 specific T cells in Aire-deficient bone marrow recipients. Supplementary Figure 6. Effects of Aire deficiency on TRP-1 Specific CD4+FOXP3+ Tregs in spleen