bluuebunny/crossref_metadata_2025 huggingface dataset:
The Evaluation of Flow Property of Alginate Impression Material Mixed with Gargle Solutions
Authors: Sastrodihardjo Sumadhi , Harahap Kholidina Imanda
Published: February 2020

The effects of antiseptic and gargle solutions mixed with the irreversible hydrocolloid alginate impression material to anti-bacterial activity and several properties had been elucidated. The flow property of the such impression has been not elucidated yet. The aim of the study was to evaluate the flow property of alginate impression mixed with gargle solution. Aroma Fine Plus alginate impression material was used and mixed with aquadest as control and Minosep, Betadine and Total Care gargle solutions. Ratio between alginate and each solutions were performed by following the producer’s guidance as 8.4gr alginate and 20ml solution. The every alginate mixtures were made in triplicate (n=3).  Measurement of flow capability was performed by using 0.5ml of alginate mix laid on glass plate covered with cellophane strip and loaded with 1kg metal for 1 minute. The major and minor diameters were measured by using digital caliper. Data were analyzed  by using one way ANOVA (α= 0.05). Aroma Fine mixed with aquadest showed the flow capability was about 26.18mm. Mixed with Minosep showed about 27.85mm, with Betadine 29.19mm and Total Care 27.11mm respectively. Statistically show a significant different  flow capability between aquadest and Betadine mixed impression (p=0.01). Minosep and Total Care gargle solutions showed insignificant different with aquadest mixed impression (p>0.05). It can be concluded that the utilizing of Minosep and Total care gargle solution as  solutions mixed with alginate impression material have no effect to flow property of the impression, except by using Betadine gargle solution.
Uji Sitotoksisitas Seng Oksida Ekstrak Allium Sativum Linn. terhadap Sel Fibroblas Gingiva Manusia
Authors: Aini Nisrina Qurrota , Agustantina Titien Hary , Rianti Devi
Published: February 2020

The use of zinc oxide eugenol in open pulps is controversial because of the cytotoxic effects of eugenol. Previous research has proven that zinc oxide Allium sativum Linn. extract can be an alternative for pulp capping material because it has antibacterial effect. The materials that applied to the oral cavity must be non-cytotoxic and biocompatible, therefore cytotoxicity testing is required of zinc oxide Allium sativum Linn. extract on human gingival fibroblast cell. To determine the cytotoxicity of zinc oxide Allium sativum Linn. extract on human gingival fibroblast cell.  Cytotoxicity test of a mixture of zinc oxide with Allium sativum Linn. extract using ratio 1:1 (group A) and 2:1 (group B), zinc oxide eugenol 1:2 (control group C). Each material is exposed to the human gingival fibroblast cells. The cytotoxicity test was tested using an MTT essay test. The density of optic formazan indicated the number of living cell. Cytotoxicity  parameters using IC50. Data were analyzed using one-way Anova test and Tukey HSD test. The number of living cells in group A= 40,400 %, group B= 50,613 % and group C= 51,247 %. There was no significant difference between zinc oxide Allium sativum Linn at a ratio of 2:1 (group B) with zinc oxide eugenol 2:1 (group C). Zinc oxide Allium sativum Linn. extract with a ratio 2:1 were not cytotoxic toward human gingival fibroblast cell.
Kista radikuler besar yang melibatkan dasar cavum nasalis
Authors: Diba Silviana Farrah , Epsilawati Lusi , Kapriani Rike
Published: February 2020

Objectives: This case will present a radicular cyst and its expansion effect, seen from cone beam CT (CBCT) 3D radiograph.
Case Report: A 32-year-old patient complained about discoloration of her upper anterior teeth and swollen gums. Periapical radiograph for preliminary examination revealed a large radiolucent area with well-defined cortical  border in periapical 21. In coronal view, the lesion extends to 22 also causes the destruction of the nasal cavity floor and palatal cortical bone. Endodontic, cyst enucleation, and bone graft was performed to the patient. After endodontic treatment, CBCT examination was performed to determine the extent of cyst lesions. 
Conclusion: Large lesion needs an adequate radiographic technique to examine anatomical structure involvement. In large cysts, CBCT examination is matter to consider.
Analisis ameloblastoma unilokuler menggunakan radiograf cone beam computed tomography (CBCT) 3D sebagai penunjang diagnosis
Authors: Saifuddin Siska Damayanti , Pramanik Farina , Firman Ria Noerianingsih
Published: February 2020

Objectives: This purpose of this  case report is to explain the imaging characteristics of unilocular ameloblastoma in CBCT 3D radiograph.

Case Report: A 32-year-old male patient came to the dentist complaining his painful right lower jaw over the past few days. Clinical examination showed extensive swelling in the posterior region of the right mandible to cause asymmetry at the inferior border of the mandibular corpus. Panoramic radiography showed radiolucent area in periapical mesial root of 46 tooth, extending to the right angular mandibular with a clearly demarcated shape,  and there was a root resorption of 47 tooth. CBCT 3D examination showed the presence of unilocular radiolucent lesion in a regular shape and a clear borderline, extending to the inferior border of the mandible and causing buccal-lingual cortical perforation accompanied with the resorption of adjacent 47 tooth.

Conclusion: CBCT is a supporting radiography that may act as a more accurate diagnostic tool for the diagnosis of unique ameloblastoma lesions.
Peningkatan Keamanan Wireless Pada Jaringan Komputer di Universitas Amikom Menggunakan Protokol IEEE802.1X
Authors: Wiratama Ichsan , Sugiartawan Putu
Published: February 2020

The access point configuration used for wireless connections in Amikom is manually configured one by one. Each access point is configured using several SSIDs based on the department that will connect to the access point. The use of multiple SSIDs in one access point turned out to have a bad effect on network performance, from the test results, for access points configured with more than four SSIDs, the connection was very slow. The security standard used for connection from the user to the access point is WPA Personal, where WPA Personal can be said to be very weak because for each SSID it will use the same user and password for all users, this is often the cause of access leaks.

To improve network security and make it easier for the author to do maintenance on the network, the author tries to use the IEEE 802.1X protocol that is connected with RADIUS and access point controllers so that the configuration and maintenance of wireless networks can be centralized, user administration and passwords can also be centralized server radius and also a better level of security using WPA Enterprise security in the IEEE 802.1X protocol.
ARADİLLER ve ARADİLBİLİM
Authors: Aray Başak
Published: February 2020

Uluslararası iletişim için tasarlanmış
planlı diller, 19. yüzyılın sonundan beri pek çok dilbilimciyi meşgul etmiştir.
Bu yazımızda, söz konusu dillerin incelemesini ve planlamasını konu edinen interlinguistik
(aradilbilim) dalını tanıtıyoruz. Dilbilim içerisinde planlı dillerin statüsü
aradilbilim literatürünün en önemli isimleri üzerinden tartışılacak, bu alanın
kısa bir tarihçesi ile güncel panoraması sunulacaktır. Güncel aradilbilim
çalışmalarının ışığında planlı diller, uluslararası örgütlerde adil iletişim
sağlamak ve küresel dil hegemonyasını zayıflatmak için üzerinde durulmaya değer
bir seçenek olarak belirmektedir.
TÜRKİYE’DEN KIBRIS’A GİDEN EĞİTİMCİ VE YAZARLARIN GÖZÜYLE KIBRIS’TA EĞİTİM HAYATI
Authors: Çapa Mesut
Published: February 2020

Türkiye Cumhuriyeti, kuruluşundan itibaren Kıbrıs Türkleriyle eğitim ve kültür alanında iletişimini sürdürmeye çalışmıştır. İngiliz idaresinin hâkim olduğu yıllarda, bazı güçlüklere rağmen Türkiye’den Kıbrıs’a öğretmenler gönderilmiştir. Bu dönemde, “Anavatan” Türkiye ile “Yavru vatan” Kıbrıs arasındaki dostluk ve kardeşlik ilişkileri ziyaretlerle pekiştirilmiştir.
1925-1927 tarihleri arasında Lefkoşa Lisesi Müdürlüğü’nde bulunan Kâzım Nami Duru, Cumhuriyet dönemiyle ilgili anılarında Kıbrıs’a da yer vermiştir. Yine aynı tarihlerde konsolosluk görevinde bulunan Ali Asaf Bey, Kıbrıs’ta eğitim hayatına büyük ilgi göstererek önemli tespitlerde bulunmuştur. Daha sonraki tarihlerde Kıbrıs’ı ziyaret etmiş olan Hasene Ilgaz, Hasan Ali Yücel ve Şemsi Belli gibi eğitimci, yazar ve siyasetçiler de gezi notlarını yayınlamışlardır. 1925-1960 yıllarını kapsayan bu anılarda, Kıbrıs’ın eğitim ve kültür hayatı, basın, ekonomik hayat, ulaşım, Kıbrıs Türklerinin Türkiye’ye bakışları gibi muhtelif konulara değinilmektedir. Kıbrıs’ta, 1959 yılına kadar İngiliz idaresinin kontrolü altında bulunan eğitim hayatı, bu tarihten itibaren Türk ve Rum toplumlarının idaresine bırakılmıştır. Bu araştırmada, 1960 yılından önce Kıbrıs Türklerinin eğitim hayatı Türkiye’den Kıbrıs’a giden eğitimci ve yazarların yayınları çerçevesinde verilmeye çalışılacaktır.
KAHRAMANLARININ ÖZELLİKLERİ BAKIMINDAN BİR DESTAN ANLATIMININ İNCELENMESİ: HAKAS DESTANI ALTIN ÇÜS
Authors: Uluışık Yaprak Pelin
Published: February 2020

ÖZ

Güney Sibirya Türk topluluklarından biri olan Hakasların “alıptığ nımah” adını verdikleri, tam tarihleri bilinmese de diğer destan örneklerinden daha da eski zamanlara dayandırılabilen ve birden çok tarihi tabakayı bünyesinde barındırdığı tespit edilebilen destan örnekleri mevcuttur. Manzum oluşu, müzik eşliğinde haycılar (destan anlatıcıları) tarafından söylenişi ve söylenişindeki kalıp ifadeler, tasvirler, tekrarlar, uyak ve redif kullanımı vb. ile tipik bir Hakas destanı olan Altın Çüs destanı, mitolojik altyapısı ve Şamanizm unsurları ile de Hakasların alıptığ nımahlarına örnek olarak gösterilmektedir. Kahramanın özelliklerinin ön plana çıkmaya başladığı, yeraltı mücadelelerinin yeraltının yeryüzündeki temsilcileri ile yeryüzünde yapılmaya başlandığı bu destanda üç ana kahraman mevcuttur: Altın Çüs, Alıp Möke ve Üzüm Han. Hakas destanları üzerine yapılan çalışmalar, destanların icrası sırasında üç kuşak anlatımının gelenek olduğunu göstermektedir. Altın Çüs destanı da Alıp Han’ın anlatımı ile başlayıp Altın Çüs’e, oradan Altın Çüs’ün yoldaşı Alıp Möke’ye ve oradan da Alıp Möke’nin oğlu Üzüm Han’a geçer. Destanda bu üç kahraman aynı anda hayattadır ve destan boyunca kahramanların üçü beraber anlatılır.
Bu makale, destan kahramanlarının doğumu, adlarının verilmesi, fiziksel özellikleri; atları, savaş giyimleri ve silahları; verdikleri mücadeleler ve savaşları; onlara yardımcı ve onların karşısında olan destan kadrosu; sihir (büyü) yapma, şekil değiştirme, ölüyü diriltme ve emçilik, bilici ve sezici olma vb. olağanüstülükleri açısından Altın Çüs destanının bir incelemesi şeklindedir. İnceleme sırasında destan anlatımındaki konu sıralamasına önem verilmiş, kahramanların özellikleri ile ilgili açıklamalar bu sıralamaya göre yapılmıştır. Kahramanların özelliklerinden söz edilirken Altın Çüs destanının nazım parçalarından da örnekler verilmiştir.
Aceitação de suplemento hipercalórico e hiperproteico por pacientes oncológicos em um hospital escola de Pouso Alegre/MG
Authors: Dias Déborah Gomes , Tiengo Andrea , Brasil e Bernardes Ana Carolina
Published: February 2020

Objetivo: Desenvolver um suplemento alimentar hipercalórico e hiperproteico e verificar a sua aceitabilidade junto aos pacientes oncológicos de um hospital escola. Métodos: Foram escolhidos aleatoriamente 60 pacientes internados nas enfermarias de um hospital na cidade de Pouso Alegre/MG. Os pacientes receberam um complemento alimentar hipercalórico e hiperproteico, acrescido de triglicerí­deos de cadeia média e após o consumo foi aplicado um questionário para avaliar a sua aceitação. Resultados: Observou-se aceitação do suplemento para ambos os sexos, entretanto mulheres de 18 a 70 anos atribuí­ram uma nota média de 6 pontos, indicando que comeriam muito frequentemente o suplemento. Os pacientes do sexo masculino com idade entre 35 e 45 anos tiveram uma melhor aderência ao suplemento e comeriam sempre, com nota média de 8 pontos. Conclusão: Os resultados sugerem que homens e mulheres aceitaram e avaliaram positivamente o produto e o quesito mais bem avaliado foi o sabor.Palavras-chave: suplementos nutricionais, desnutrição proteico-calórica, terapia nutricional.
Antropometria e consumo alimentar: identificador do estado nutricional de idosos
Authors: Miranda Rozinéia de Nazaré Alberto , De Paiva Marinara Borges
Published: February 2020

O estado nutricional é um importante marcador da saúde geral do idoso. Objetivou-se neste estudo identificar através da antropometria e do consumo alimentar o estado nutricional de idosos frequentadores de uma ONG. Estudo transversal e descritivo de informações socioeconômicas e demográficas, antropometria e consumo alimentar. Participaram da pesquisa 101 idosos, 54,5% do sexo feminino, com faixa etária predominante entre 60 e 70 anos, solteiros e viúvos (36,6%), respectivamente, 53,5% declararam ter de 1 a 8 anos de estudos e 52,5% possuí­rem renda de um salário mí­nimo. Ocorreu predominância de excesso de peso através do í­ndice de massa corporal, eutrofia pela circunferência braquial e desnutrição pela prega cutânea tricipital. Alto consumo diário de alimentos energéticos: arroz (90,1%) seguido pela farinha de mandioca (44,6%) e pão (44,6%). A respeito dos alimentos proteicos, 68,3% afirmaram consumir leite diariamente, 54% e 38% consumem de 1 a 3 vezes/semana carne vermelha e aves, respectivamente, e 39,6% relataram consumir feijão diariamente. O consumo de vegetais do grupo A foi o mais frequente (35,6%) entre os idosos. Os idosos apresentaram estado nutricional e hábitos alimentares inadequados, o que reforça a necessidade de orientações nutricionais especifica para este grupo etário.Palavras-chave: idosos, antropometria, consumo alimentar.
Depressão e disbiose
Authors: Saraiva Flávia Renata de Sousa , De Carvalho Luiza Marly Freitas , Landim Liejy Agnes dos Santos Raposo
Published: February 2020

O presente estudo tem como temática a relação entre depressão e disbiose por entender que os alimentos influenciam no funcionamento do corpo e da mente. O objetivo foi realizar uma revisão integrativa sobre disbiose e presença de transtorno depressivo. Para a seleção da amostra definiu-se critérios de artigos indexados de 2014 a 2019, publicados em periódicos nacionais e internacionais, disponibilizados na í­ntegra em lí­ngua portuguesa e inglesa. A coleta de dados foi realizada na base Biblioteca Virtual de Saúde (BVS), Lilacs, Scielo, PubMed, e Google Acadêmico, utilizando os seguintes descritores: Disbiose; Depressão; Consumo Alimentar. A busca resultou em 23 artigos após utilização dos critérios de inclusão e exclusão; restaram 6 artigos para análise, interpretação e discussão. Observou-se que nos estudos analisados pode-se perceber que há uma correlação entre disbiose e depressão. De modo que o envolvimento entre nutrientes e a depressão tem um papel fundamental na gênese da depressão. Conclui-se que a deficiência ou carência de nutrientes em decorrência dos distúrbios da microbiota leva a diminuição de serotonina, e consequentemente a quadros depressivos. A alimentação saudável torna-se primordial para o equilí­brio da flora intestinal e para o tratamento da depressão.Palavras-chave: consumo alimentar, depressão, disbiose
Diferentes modalidades de exercí­cio não influenciam a sensação de fome, consumo calórico e de macronutrientes em mulheres pós-menopáusicas
Authors: Carteri Randhall Bruce , Krüger Renata Lopes , Gross Júlia Silveira , Reischak-Oliveira Álvaro , Lopes André Luiz
Published: February 2020

Durante a menopausa ocorre ganho de peso e massa adiposa. Paralelamente, ocorre uma diminuição da ingestão calórica, acompanhada por aumento da sensação de fome, uma consequência natural do envelhecimento. Considerando que exercí­cios são importantes para a promoção de saúde e podem influenciar no balanço energético, o objetivo do presente estudo foi avaliar se a ingestão calórica e de macronutrientes é influenciada agudamente por diferentes modalidades de exercí­cio em mulheres pós-menopáusicas. Nove mulheres pós-menopáusicas, com idade entre 52 e 64 anos, com IMC entre 20 kg/m2 e < 30 kg/m2 participaram do estudo. Foi realizada avaliação antropométrica e de capacidade de exercí­cio aeróbico. As sessões de teste foram compostas de: descanso na posição supino por 30 minutos (sessão controle), exercí­cio aeróbico realizado durante 30 minutos de exercí­cio em cicloergômetro com intensidade de 60% do VO2pico (exercí­cio aeróbico) ou exercí­cio de força realizando sete exercí­cios de força com 3 séries de 15 RM e intervalo entre séries de um minuto (exercí­cio de força). Nossos resultados mostram que não houve influência do exercí­cio na sensação de fome, densidade calórica, composição de macronutrientes em uma refeição livre. De uma maneira geral, nossos achados estão de acordo com a literatura indicando que não há aumento compensatório aguda da fome ou da ingestão de alimentos após exercí­cio.Palavras-chave: menopausa, apetite, saúde.
Ефект етил 2-(хіназолін-4-іламіно)-4,5,6,7тетрагідробензо[ b ]тіофен-3-карбоксилат гідрохлориду на ДНК, РНК, білки хроматину й показники стану антиоксидантної системи в карциномі Герена та незмінених тканинах матки щурів
Authors: Бондаренко Л. Б. , Карацуба Т. А. , Хавич О. О. , Шаяхметова Г. М. , Шарикіна Н. І. , Коваленко В. М. , Левицька Н. В. , Полковниченко К. В. , Калачінська М. М.
Published: February 2020

Стандартні підходи до вивчення специфічної фармакологічної дії та токсичності протипухлинних засобів не дають змоги провести детальну комплексну оцінку метаболічних змін поза пухлиною, хоча давно стало очевидним, що неспецифічна дія хіміотерапії може на тлі пригнічення росту пухлин викликати незворотні зміни в організмі, які надалі суттєво погіршать його шанси на видужання. Ці обставини зумовлюють актуальність включення в доклінічні дослідження нових протипухлинних засобів вивчення їхніх ефектів як на пухлини, так і на прилеглі не уражені тканини, для подальшої оптимізації хіміотерапії. Мета дослідження – порівняти вплив етил 2-(хіназолін-4-іламіно)-4,5,6,7-тетрагідробензо[b] тіофен-3-карбоксилат гідрохлориду (ЕХТК) на ДНК, РНК, білки хроматину, процеси фрагментації ДНК, вміст ТБК-реактантів і SН-груп у карциномі Герена та незмінених тканинах матки. Дослідження впливу ЕХТК проводили на білих щурах – самицях лінії Вістар. Тварини були розподілені за методом рандомізації на 3 групи по 6 тварин у кожній: 1 – інтактні щури; 2 – позитивний контроль (карцинома Герена); 3 – карцинома Герена + ЕХТК (24,37 мг/кг). Вивчення впливу ЕХТК на ДНК, РНК, білки хроматину, процеси фрагментації ДНК, вміст ТБКреактантів та небілкових і пов’язаних з білками SH-груп у карциномі Герена та незмінених тканинах матки показало, що дана сполука вірогідно змінювала більшість досліджуваних показників як порівняно з інтактними тваринами, так і з карциномою Герена без лікування. Ефект ЕХТК на фрагментацію ДНК не відзначався вузькою тканинною специфічністю. Специфічність впливу ЕХТК на клітини пухлин була найвираженішою у випадку змін вмісту ДНК, РНК, білків хроматину, а також ТБК-реактантів, небілкових і пов’язаних з білками SH-груп.
Изучение эффективности липофильного экстракта травы Achillea collina J. Becker ex Reichenb на модели термического ожога у крыс
Authors: Дуюн И. Ф. , Мазулин А. В. , Беленичев И. Ф. , Абрамов А. В.
Published: February 2020

Цель исследования – изучить эффективность липофильного экстракта травы тысячелистника холмового Achillea collina J. Becker ex Reichenb (ЛЭТП) на модели термического ожога у крыс. Исследования проводили на 40 белых беспородных крысах обоего пола массой 200–240 г. Термический ожог моделировали контактным способом под легким эфирным наркозом. Исследуемый ЛЭТП и референтный препарат – мазь с маслом облепихи наносили на раневую поверхность 1 раз в сутки в течение 50 сут. Ранозаживляющую активность оценивали по таким показателям, как ликвидация перифокальной реакции, отторжение струпа, появление грануляции, начало краевой эпителизации, скорость полной эпителизации. В сыворотке крови твердофазным иммуносорбентным сэндвидж методом ELISA определяли маркеры окислительного стресса (нитротирозин) и воспаления (С-реактивный белок, интерлейкин-1b). В ходе эксперимента на крысах с моделью термического ожога установлено, что ЛЭТП и мазь с маслом облепихи оказывали значительное ранозаживляющее действие, ускоряя темпы регенерации. Полное заживление ожоговой раны под влиянием ЛЭТП и мази с маслом облепихи наступало на 24–26 сут по сравнению с 46 сут в контрольной группе животных. В случае применения ЛЭТП и мази с маслом облепихи содержание нитротирозина в сыворотке крови уменьшалось на 43,2 и 47,0 %, С-реактивного белка – на 47,3 и 24,8 %, интерлейкина-1b – на 54,3 и 26,2 % соответственно по сравнению с показателями контрольной группы. Полученные результаты экспериментально обосновывают наличие ранозаживляющей активности ЛЭТП и позволяют рекомендовать его как перспективное лекарственное сырье для производства компонентов фитопрепаратов с ранозаживляющей активностью.
Експериментальне дослідження кардіопротекторної дії 2-гідрокси-N-нафтален1-іл-2-(2-oксо-1,2-дигідро-індол-3-іліден)ацетаміду
Authors: Луценко Р. В. , Цивунін В. В. , Койро О. О. , Лар’яновська Ю. Б.
Published: February 2020

Сучасні принципи лікування коморбідних пацієнтів із серцево-судинними захворюваннями та тяжкими психічними розладами спрямовані на обмеження поліпрагмазії. Тому перспективним є пошук препаратів полімодальної дії, здатних одночасно виявляти як кардіопротекторну, так і нейромодулювальну дію. У цьому аспекті привертають увагу похідні 2-оксоіндолін-3-гліоксилової кислоти, яким притаманний широкий спектр нейротропної активності. Мета дослідження – визначити вплив потенційного нейротропного засобу – 2-гідрокси-N-нафтален-1-іл-2-(2-oксо-1,2-дигідро-індол-3-іліден)-ацетаміду (умовна назва – сполука 18) – на перебіг експериментального ураження серця щурів. Досліди проведено на 38 статевозрілих рандомбредних білих щурах самцях. Адреналіновий міокардит моделювали шляхом одноразового підшкірного введення розчину адреналіну гідротартрату («Адреналін-Дарниця», розчин для ін’єкцій, 1,8 мг/мл, ФК «Дарниця», Україна) у дозі 1 мг/кг. Досліджувану речовину в дозі 12 мг/кг і препарат порівняння етилметилгідроксипіридину сукцинат («Армадин», розчин для для ін’єкцій, 50 мг/мл, ЗАТ «Лекхім-Харків», Україна) у дозі 100 мг/кг вводили внутрішньоочеревинно в лікувально-профілактичному режимі за 30 хв до і через 1 год після моделювання ураження міокарда. Функціональний стан міокарда оцінювали за показниками електрокардіограми. Виразність деструктивних процесів у серцевому м’язі визначали за активністю МВ-фракції креа тинфосфокінази, маркерних ферментів цитолізу – аспартатамінотрансферази та аланінамінотрансферази в плазмі крові щурів. Інтенсивність процесів пероксидного окиснення ліпідів визначали за вмістом активних продуктів, що реагують з тіобарбітуровою кислотою, у плазмі крові та гомогенаті міокарда щурів, стан антиоксидантної системи – за активністю супероксиддисмутази та каталази в гомогенаті міокарда. Досліджували морфологічний стан серця щурів. Встановлено, що адреналіновий міокардит у щурів супроводжується як функціональними (електрокардіографічними та біохімічними) змінами, так і дифузними морфологічними ознаками ішемії міокарда (спазм тонкостінних судин, венозний застій), дистрофії серцевого м’яза (набряк, втрата поперечної посмугованості) і некрозу кардіоміоцитів. У той самий час сполука 18 за умов адреналінового міокардиту чинить виразну кардіопротекторну дію, що її встановлено за відновленням електрокардіографічних показників і біохімічних індикаторів функціонального стану міокарда, а також морфологічно – за редукцією проявів ішемії та дистрофії серцевого м’яза тварин. Визначено також, що кардіопротекторний ефект сполуки 18 значно перевищує дію препарату порівняння етилметилгідроксипіридину сукцинату за експериментального адреналінового ураження серця щурів.
The Implementation Analysis of Clinical Governance by the Medical Committee at Deli Serdang Hospital
Authors: Ratna Wulandari  , Zulfendri  , Surya Utama
Published: February 2020

Clinical governance aims to maintain and improve the quality of medical services for patients and protect patients from the risk of unexpected events as regulated in Law Number 44 of 2009 concerning Hospitals and Minister of Health Regulation Number 755 / MENKES / PER / IV / 2011 regarding the implementation medical committee at the hospital. The medical committee is one of the hospital's instruments that has an important role in implementing clinical governance so that the medical staff at the hospital is maintained professionally. In implementing clinical governance in hospitals, it is done by carrying out credentials, monitoring the quality of the medical profession, and maintaining the ethics and discipline of the medical profession. This type of research is qualitative in-depth interviews. Informants were selected using a purposive technique. The subjects in this study were informants relating to the medical committee. The results showed that the implementation of clinical governance in Deli Serdang Hospital was not going well. This can be seen from the implementation of medical committee activities that are not in accordance with the Minister of Health Regulation No. 755 / MENKES / PER / IV / 2011 concerning the implementation of medical committees in hospitals. The work program carried out by the medical committee at Deli Serdang Hospital is deemed not in accordance with the expected target. This is due to the lack of planning and budget that supports the implementation of clinical governance in Deli Serdang Hospital. The implementation of clinical governance by the medical committee in medical services at Deli Serdang Hospital has not been running well. Thus, good planning and budgeting is needed to strengthen the activities of the medical committee in achieving good clinical governance in Deli Serdang Hospital.
Hygienic and toxicological aspects of wild-growing mushroom poisoning (Review of literature data and the results of own research)
Authors: Kalashnikov A.A. , Kurdil N.V. , Lutsenko O.H. , Voytenko H.M. , Bogomol A.G.
Published: February 2020

ABSTRACT. Unsettling statistics of poisoning resulting from the use of wild-growing mushrooms necessitates a more detailed study of the life-threatening causes in human and determination of preventive measures. Objective. Analysis of the structure, changes over time and causes of poisoning by wild-growing mushrooms among the population of Kyiv and the Region of Kyiv in recent years. Materials and Methods. Cases of mushroom poisoning (ICD–T62.0) among the adult population of Kyiv; statistic data from the Ministry of Health of Ukraine, the State Emergency Service of Ukraine and the toxicological centre of the Kyiv City Clinical Emergency Hospital. Study methods used: analytical, systemic and comparative analysis. Results and Discussion. In the general structure of acute poisoning, cases of mushroom poisoning account for 3%. The average hospital mortality rate is 9.3%. Among the aetiological factors, poison amanita prevails, conditionally edible mushrooms are in the second place, and edible mushrooms, which acquired toxic properties due to anthropogenic pollution of the environment are in the third place. The following abnormal conditions were found in poisoned persons: toxic gastroenterocolitis (81.4%), toxic neuropathy (2.1%), toxic hepatonephropathy (16.2%). It was established that the risk groups for poisoning associated with mushrooms are the population with a lack of understanding of the possible danger of eating mushrooms: unskilled workers, unemployed, school and preschool children and inhabitants of large cities who have no stranger in picking mushrooms (mainly men). In general, poisoned persons showed a low level of awareness of the danger and lack of knowledge about the means of preventing poisoning at the stages of picking, sorting and preparation of mushrooms and the rules of primary health care. Low efficacy of prevention against seasonal mushroom poisoning remains one of the factors of high morbidity and mortality. Conclusion. The study revealed that seasonal poisoning with wild-growing mushrooms remains an important medical and social problem in most regions of Ukraine. In recent years, measures of sanitary supervision and control in the field of prevention of seasonal mushroom poisoning have been significantly worsened. The situation requires the restoration of an integrated approach to preventive actions to prevent harm to life and health when eating wild-growing mushrooms. Key Words: sanitary and hygienic monitoring, mushroom poisoning.
Russian military agression against Ukraine through the prism of hazard of hostile military and anthropogenic influence on environment
Authors: Avdoshyn I. , Velychko M.V. , Kyryliuk O. , Kryvych M.
Published: February 2020

ABSTRACT. The paper deals with the problem issues of the development of new risks and threats to the national security of Ukraine of environmental nature in cause-and-effect relation to military aggression of Russia against Ukrainian country in the Anti-Terrorist-Operation / Joint-Forces-Operation zone. Any type of anthropogenic influence, specifically at wartime is a threat to environment and it can cause an ecological disaster on a planetary scale. The environmental issues are becoming a constituent part of the most important political and law-making processes: new economic order, human rights, and common European process. It is always an independent element requiring deep scientific comprehension. The paper highlights, that the issue of preconditions of the threats to environmental security in the context of deterioration of environmental situation in the zone of AntiTerrorist-Operation / Joint-Forces-Operation resulting from the direct military aggression of Russia against Ukraine has never been researched into. The main idea of this paper is to make known the facts of environmental problems to the international community and to work out proposals on amending and supplementing some legal documents on state security because the environmental pollution of the territory of Ukraine caused by Russian military aggression is becoming more serious. These abuses and breaches committed by Russia result in damage to Ukraine’s natural environment and serve as a precondition for war crimes, linked to a survival of civilians both in the zone of military operation and in neighbouring districts. To determine and assess the environmental damage from Russia’s aggressive actions and military equipment and weaponry applied it is necessary to perform together with foreign specialists an environmental assessment of inflicted damage. The paper will provide an opportunity to codify and determine the preconditions, risks, threats and specific actions in case of aggression from any state which results in deterioration of environmental situation and causes damages to natural environment.

Key Words: threats, environmental security, international environmental law, natural environment.
Analysis of food rates of students of the faculty of physical education
Authors: Tymofiichuk I.R. , Dotsiuk L.H. , Semenenko S.B. , Boreiko L.D. , Semenenko N.Yu.
Published: February 2020

ABSTRACT. It is well known that health depends on many factors: socio-economic and environmental, age and gender, heredity and lifestyle. One of the most important components of a healthy lifestyle is a healthy diet.

The popularity of fast food products containing a large variety of additives, dyes, modified components is increasing in students. Often, students eat extremely irregularly, having a snack on the go, on the go. Students of the Faculty of Physical Education, in addition to mental ones, also have considerable physical activity, which requires an increase in the energy value and quantity of trace elements of proteins and vitamin composition in the diet. Analysis of the nutritional components of students of the Faculty of Physical Education revealed a number of problems in the nutrition of students.

We set a goal to evaluate the nutrition of students in the Faculty of Physical Education.

Respondents' survey and survey methods were used. Calories and quality composition of diets were calculated by reference tables.

Analyzing the diets of the students of the Faculty of Physical Education, it was found that in their diets insufficient amount of foods with fiber, insufficient amount of low-fat meat, which slows muscle growth and reduces functionality. Insufficient consumption of vegetables and fruits does not satisfy the need for micro and macronutrients, vitamins

Key Words: food rations, rational nutrition, energy value of foods, vitamins.
Ethnopolitical Contradictions in Katerynoslav Region in the Conditions of the Systemic Crisis of the Russian Autocracy of the End of XIX - BEGINNING OF THE XX CENTURY
Authors: Шляхов O.
Published: February 2020

In the post-reform period, the Katerynoslav province was used as a locomotive of capitalist transformations, and on the other hand represented polyethnic and poly-denominational territories inhabited by Ukrainians, Russians, Jews, Germans, Poles, Greeks, Tatars, Bulgarians. etc. Such diversity could not but affect the ethnic relations in the region, which left a significant imprint on them. These relationships, in turn, were characterized by both relationship development and mutual influences, and a sufficiently high level of conflict. In particular, the author analyzes the causes and manifestations of superechtas between representatives of different ethnic groups that inhabited Katerynoslav region at the end of XIX - early XX centuries.Thus, it is emphasized that the rupture of social ties and impoverishment of a large part of the population during the transition from traditional to industrial society objectively created the basis for the spread of xenophobic and nationalist sentiments. At the same time, attention is drawn to the fact that at this time tsarism continued to build its intrinsic policy on the principles of the great power, the basis of which was known the «Uvarov» triad – «autocracy, Orthodoxy, nationality», in particular, when the official ideology was counted ethnic Ukrainians to Russians. Therefore, in the confines of a large-scale, chauvinistic policy, the Ukrainians were demolished and assimilated, and the rights of the Jewish population and representatives of other ethnic groups inhabiting the empire were restricted at the legislative level.Conflicts on the national soil in the region have seen an increase in the number of riotous actions against the local Jewish population, as well as the launching of anti-German campaigns, especially during the First World War. In addition, numerous disputes in Katerynoslav province have arisen between Ukrainians and Russians, as well as between local workers and foreign management personnel, who appeared in large numbers at the factories and mines of the region in the modern period. All this led to the destabilization of the socio-political situation, becoming a significant component of the revolutionary crisis that swept the Russian Empire in the early twentieth century.
THE FIGHTING OF THE CARALIAN AUTHORITIES OF CZARISM WITH THE UKRAINIAN POLITICAL PARTIES OF THE ADVENTURES IN THE YEARS OF THE FIRST THE RUSSIAN REVOLUTION
Authors: Сарнацький О.
Published: February 2020

The actions of the juridicalbranch of power of the autocracyin relationto the activity of oppositional political parties founded at the end of the 19-th – beginning of the 20-th centuries in Russian Empire and headed liberatoryand national-liberatorymovement in the country, whichwere aimed at ceaseof their politicalactivity and occurred simultaneously with administrative repressions over political opponents of the existing system.After all, the law in force in the empire until October 1905 did not allow the existence and activity of any political partiesin the country. In the conditions of the lawfulness proclaimed by tsarism (even with all its limitations), the authorities were forced to resort to court assistance. The accusatory verdict was the most severe punishment.During the First Russian Revolution, which began at this time, the judiciary in every way promoted the local administrative authorities in defining its properties of the committed «criminal acts» and punishing the perpetrators. More or less «condescending» sentences of judges against representatives of the revolutionary and national liberation movements in 1905 forced the tsarist judiciary to review such a judicial procedure and strengthen its harshness on defendants who committed crimes against the authorities. Subsequently, the Ministry of Justice issued a variety of secret circulars, aimed at intensifying the struggle of the courts against the revolutionary movement, and the court machine of the tsar began to increase pressure. The law of March 18, 1906, restricted the publicity of the court and the timeframe for hearing cases, abolished the requirement to record witnesses’ statements in the minutes and to motivate sentences. On May 11, 1906, the Ministry of Justice issued a circular to the courts No. 2015, which stated that cases of the most serious state crimes should be heard in the special presence of the court chamber behind closed doors. It consisted of a provincial nobleman, a mayor, and state representatives. The judicial power of the autocracy was actively “working”, punishing representatives and supporters of Ukrainian political parties when their activities were related to elections to the Second State Duma. At the same time, the royal court severely punished representatives of Ukrainian political parties, even if they were considered underage by the laws of the Russian Empire, without even considering some of them as guilty.
PARTICIPATION OF INTELLIGENCE IN THE WORK OF LOCAL SELF-GOVERNMENT AUTHORITIES IN 1941-1943.
Authors: Борисов B. , Левін О.
Published: February 2020

The processes that took place in the public life of our country at those stages of its historical development, when the issue of preserving the Ukrainian statehood, were of great interest in the context of the implementation of the “decentralization” reform and the growing role of local self-government in modern Ukraine. In this context, the issues of participation of the Ukrainian intellectuals in the work of local self-government bodies (“Ukrainian subsidiary administrations”) during the difficult period of the German-fascist occupation of the territory of Ukraine in 1941-1944 are of current relevance. In the first weeks of the war with the Soviet Union, the fascist leadership decisively eliminated all attempts by Ukrainian nationalists to recreate the Ukrainian state in any form. The occupied territories were artificially divided into several administrative territorial units. On August 20, 1941, the Reich Commissariat of Ukraine was formed, which included ten occupied regions of Ukraine, including Dnipropetrovsk.On the initiative of P.T. Sokolovsky, The “Committee of Managing Propagandists” was established in the city and solemnly celebrated the second anniversary of “liberation” of Dnepropetrovsk “from the Bolsheviks” on August 25, 1943. The views of P.T. Sokolovsky were shared by many of his subordinates. Propaganda of the ideas of the new totalitarian ideology certainly met the requirements of the occupying power. Analyzing the article, we can conclude that the activities of the local intellectuals in the “Ukrainian Supplementary Authority” of Dnepropetrovsk were fully subordinated to the economic needs of the occupiers. However, the city government resolved the issues of social security of the population, preservation of the infrastructure and economic objects of the city by serving the occupying power. That is why the study of the positive aspects of the participation of the intellectuals in the work of the city government of Dnepropetrovsk in the complex historical period of 1941–1943 is a prospect for further investigation of this problem.
MILITARY COMMEMORATIVE PRACTICES AS A COMPONENT OF THE HISTORICAL MEMORY OF THE UKRAINIAN PEOPLE ABOUT SECOND WORLD WAR
Authors: Ковальська-Павелко І.
Published: February 2020

The analysis shows that military commemorative practices, as a component of the historical memory of the Ukrainian people of World War II, are sufficiently diverse and mainly aimed at uniting society around key issues of state formation. It is established that the essential feature of commemoration is the creation of shared memories through the elaboration of rituals of perpetuation (worship, celebration, etc.) of certain persons and events, the construction of “places of memory” (P. Nora). Commemoration, which is defined as the purposeful process of preserving the memory of events significant to the nation, is realized through commemorative practices – a set of ways that contribute to the consolidation, preservation and transfer in society of its historical past. The most common commemoration practices are the erection of monuments, the creation of museums and memorials, commemorations at national and local levels, commemoration of historical documents, and more.Accordingly, in the context of the formation and reproduction of the historical memory of the Ukrainian people, the militaristic commemorative practices of World War II are divided into three groups, depending on the level of memory and the peculiarities of historical development. In particular, the first group is represented by local forms of militaristic commemoration, initiated by family members, friends and veterans themselves, who collectively represent a group’ collective memory of a war that proclaimed the nation’s reconciliation with its heritage, military losses through the expression of grief, and mourning (accounts for the 40-50s of the twentieth century); the second group is a commemorative practice, the creation of which was initiated by the central authorities (president, parliament, government) and contained a collective memory of war at the national level, which was accompanied by the heroization and symbolization of the Great Victory (in the 1960-1970’s); the third group is represented by sources of personal origin, capable of actualizing the representations of war on specific examples, there is a combination of elements of the previous groups (periods) when, together with the ideological onset of the state on social (historical) memory, the expansion of memory space into everyday life, there is an attempt to return personal memory, inherent in the early (post-war) period, when the emphasis is on sacrifice, not just on the heroization of the events of World War II.
Australian vaccine preventable disease epidemiological review series: invasive Haemophilus influenzae type b disease, 2000–2017
Authors: Maguire Julia E , Beard Frank , Méder Kelly , Dey Aditi , Macartney Kristine , McIntyre Peter
Published: February 2020

Introduction
Invasive Haemophilus influenzae type b (Hib) disease is rare in Australia following vaccine introduction in 1993. Two deaths in vaccinated children in 2017, and the Hib booster dose moving from age 12 months to 18 months in 2018, prompted this review.
Methods
Hib Case Surveillance Scheme 2000–2017 data were used to calculate incidence, incidence rate ratios (IRR) and vaccine failure (VF) trends. We used denominators from the Australian Immunisation Register to calculate incidence in immunised and unimmunised children.
Results and Discussion
All-age national invasive Hib disease incidence halved from 0.13 per 100,000 population in 2000 to 0.06 in 2017. Of 345 cases notified in 2000–2017, 153 were born post-2000, with 51 (33%) Aboriginal and Torres Strait Islander (Indigenous), and compared with non-Indigenous children IRR was 8.34 (95% CI: 5.83–11.79), with no evidence of decrease. Overall case fatality rate was 12.4% (19/153); 6 cases had underlying medical conditions. The overall incidence of invasive Hib disease was over 8 times higher (16.6 per 100,000) in children with no recorded doses than in children with ≥1 vaccine dose (1.9 per 100,000). VF criteria were met in 65/145 (45%) cases aged >8 weeks, of whom 7 (11%) were immunocompromised and 6 (9%) died, with no evidence of VF increase over time.
Conclusion
Overall, invasive Hib disease incidence declined by 55% from 2000 to 2017, but marked disparity persists between Indigenous and non-Indigenous children. Following moving the fourth dose from 12 to 18 months in 2018, monitoring of 3-dose VFs will be important, especially in Indigenous children.
Australian Gonococcal Surveillance Programme Annual Report, 2018
Authors: Lahra Monica M , Enriquez Rodney P , George C R Robert
Published: February 2020

The Australian Gonococcal Surveillance Programme (AGSP) has continuously monitored antimicrobial resistance in clinical isolates of Neisseria gonorrhoeae from all states and territories since 1981. In 2018, there were 9,006 clinical isolates of gonococci from public and private sector sources tested for in vitro antimicrobial susceptibility by standardised methods. This was the highest annual total of isolates tested since the inception of the AGSP. The current treatment recommendation for gonorrhoea, for the majority of Australia, remains dual therapy with ceftriaxone and azithromycin. Decreased susceptibility to ceftriaxone (minimum inhibitory concentration (MIC) value ≥0.06 mg/L) was found nationally in 1.73% of isolates. The highest proportions were reported from Tasmania and non-remote Western Australia (7.3% and 2.1% respectively). In 2018 two extensively drug-resistant isolates were reported from Queensland patients. These two isolates, with ceftriaxone MIC values of 0.50 mg/L, high-level resistance to azithromycin (MIC ≥ 256 mg/L), and resistance to penicillin and ciprofloxacin were identified and reported to the World Health Organization as isolates of international significance. Resistance to azithromycin (MIC value ≥1.0 mg/L) was found nationally in 6.2% of isolates, lower than the 9.3% reported in 2017, but more than double the proportion reported in 2015 (2.6%). The highest proportions were reported from the Australian Capital Territory (8.7%), Victoria (8.3%), and New South Wales (6.5%). High-level resistance to azithromycin (MIC value ≥256 mg/L) was reported in nine isolates nationally in 2018: four from New South Wales, three from Victoria, and two from Queensland.
The proportion of isolates resistant to penicillin in non-remote Australia ranged from 8.8% in non-remote Northern Territory to 44.1% in South Australia. In remote Northern Territory penicillin resistance rates remain low (1.9%), and higher in remote Western Australia (6.5%).
The proportion of isolates resistant to ciprofloxacin in non-remote Australia ranged from 10.3% in non-remote Northern Territory to 48.3% in South Australia. Ciprofloxacin resistance rates remain comparatively low in remote Northern Territory (1.9%) and remote Western Australia (4.6%).
PENINGKATAN PRODUKSI ULAT JERMAN MELALUI KOMBINASI PEMANFAATAN LIMBAH SAYURAN PASAR PADA FORMULASI MEDIA PAKAN YANG BERBEDA
Authors: Santoso Erik Priyo , Afrila Akhadiyah , Fitasari Eka
Published: February 2020

Waste vegetable of traditional market provided very abundant and rarely used. German mealworm known as giant meal worms are the larvae of insects named Zhopobas morio parent has a size larger than the hongkong mealworm. The purpose of this study was to determine the application of vegetable waste in feed media of German mealworm which has a different nutrient content. This experiment using a completely randomized design (CRD) factorial design with treatment G1P1 (GE 4000 kcal / kg, PK 10%), G1P2 (GE 4000 kcal / kg, PK 12%), G1P3 (GE 4000 kcal / kg, PK 14% ), G2P1 (GE 4500 kcal / kg, PK 10%), G2P2 (GE 4500 kcal / kg, PK 12%), G2P3 (GE 4500 kcal / kg, PK 14%), G3P1 (GE 5000 kcal / kg PK 10 %) G3P2 (GE 5000 kcal / kg PK 12%), G3P3 (GE 5000 kcal / kg PK 14%), each treatments replicated 3 times. The results of the research showed that the application of vegetable waste in german worm feed media is able to increase the use of feed concentrates containing gross energy and crude protein low. Vegetable waste treatment in feed media which containing gross energy of 4000 kcal / kg and 14% crude protein showing the highest value on dry matter feed intake, weight of the harvest, and worm weight gain.