bluuebunny/crossref_metadata_2025 huggingface dataset:
Predictors of Relapse and Survival in Testicular Germ cell Tumors in Children
Authors: Ali Sajid , Tariq Latif  , Muhammad ali  , Shazia perveen  , Muhammad bilal shafiq  , Muhammad abu bakr
Published: April 2023

Background: Testicular germ cell tumors are common solid organ malignancies in children with a survival rate of more than 90 %. This study aims to assess the predictors of relapse and survival in testicular germ cell tumors in children.

Methodology: A retrospective review was conducted on children up to the age of 18-years from January 2010 to December 2020 with a diagnosis of primary testicular germ cell tumors. Factors related to relapse and survival like age, baseline levels of tumor markers in serum and on relapse, stage at diagnosis, histological type, tumor laterality & size of the tumor in testicular germ cell tumors were analyzed. The data was entered into SPSS version 20. Statistical significance was set at a p-value ≤0.05.

Results: A total of 115 patients with a mean age of 5.42+ 1.54 years having testicular germ cell tumor were treated. Seventeen patients (14.7 %) had relapse of disease. Relapse was highest in patients with stage I disease (64.7 %). Yolk sac tumor was the most common pathology that was noted in twelve (70 %) patients. The most common site of relapse was the retroperitoneum (70 %). Age of patient, stage of disease, and lymphovascular invasion were significant predictors of relapse and survival in testicular germ cell tumors.

Conclusion: Management of patients with testicular germ cell tumors requires standardized follow-up protocol for early detection and treatment of disease relapse. Complete surgical excision with meticulous control of the residual disease is critical to prevent disease relapse.

Keywords: Chemotherapy, Children, Outcome, Relapse, Testicular Tumor
Large gallbladder Removed by Laparoscopic Cholecystectomy A Case report
Authors: Ullah Muneeb , Murad Muhammad Faisal , War Adil Shafi , Aqsa Adeel
Published: April 2023

Gallbladder stones impacted at neck of gallbladder can result in acute calculous cholecystitis with mucocele gallbladder. Laparoscopic cholecystectomy is performed in such cases as an emergency surgery. We present a case long gallbladder with mucocele formation that was managed by laparoscopic approach. The gallbladder removed was 27.8cm in length. This is the longest gallbladder removed by laparoscopic cholecystectomy in Pakistan so far. The patient had uneventful recovery.
Atomic layer deposition and its derivatives for extreme ultraviolet (EUV) photoresist applications
Authors: Le Dan N. , Park Taehee , Hwang Su Min , Kim Jin-Hyun , Jung Yong Chan , Tiwale Nikhil , Subramanian Ashwanth , Lee Won-Il , Choi Rino , Sung Myung M. , Nam Chang-Yong , Kim Jiyoung
Published: April 2023

Solution-processed photoresists have been forerunners in semiconductor patterning for decades. Even with the drastic reduction in photolithography wavelength, traditional spin-on resists still support the fabrication of the most advanced, sub-5 nm node logic and memory devices using EUV lithography (EUVL) (λ = 13.5 nm). However, trade-off between resolution, sensitivity, and roughness in the conventional resists pose a critical challenge in the race towards device downscaling to 1 nm node. While great efforts are being made to improve spin-on EUV photoresist performance, there has been emergence of new approaches focused on developing novel resists via vapor-phase processing routes, such as atomic layer deposition (ALD) and its analogs. This review summarizes recent advances in EUVL photoresist development based on ALD and its derivative techniques, which include ALD-based inorganic–organic dry resists and hybrid resists synthesized by infiltrating conventional spin-on resists. Despite being in the early stage, initial studies have shown the great potential of ALD applications in EUVL photoresist development.
“HISTOPATHOLOGICAL STUDY OF THYROID NEOPLASMS WITH SPECIAL REFERENCE TO EXPRESSION OF GALECTIN-3 IN THYROID NEOPLASMS IN A TERTIARY CARE CENTRE”
Authors: Choudhury Manjula , Sharma Shrutilekha
Published: April 2023

Background: Globally, the number of thyroid cancer cases was estimated to be 586,000, ranking it 9th in 2020 and the incidence rate in women is
10.1 per 100,000 which is 3-fold higher than that in men (1). Benign neoplasms outnumber thyroid carcinomas, commonly occurring during 3rd to
6th decades of life. Despite histopathology being the mainstay for diagnosis, immunohistochemical markers have been invariably used in the
recent years to aid in cases posing morphological diagnostic dilemma. To st Aims and objectives: udy the histopathological spectrum of thyroid
neoplasms and expression of Galectin-3 in thyroid neoplasms. This is a one-year c Methodology: ross-sectional study (2021-2022) carried out in a
tertiary care hospital of North East India. A total of histopathologically diagnosed 70 cases were studied and evaluated for immunohistochemical
expression of Galectin-3. Majority (58.50%) of thyroid neoplasms were found to be benign, mostly Results: affecting the age group of (31- 40)
years with female: male ratio being 7.75:1. Amongst the benign cases, all were diagnosed as follicular adenoma and amongst the malignancies,
conventional papillary thyroid carcinoma constituted majority of the cases (58.62%). Galectin-3 was expressed signicantly in the malignant cases
and the maximum expression was noted in 15 out of 17 cases (88.23%) of conventional papillary thyroid carcinoma. Thyroid Conclusion:
neoplasms are highly curable with early detection and appropriate management. Hence, in diagnostically challenging cases, the utility of
immunohistochemical markers along with the histomorphological interpretation becomes important.
COVID – 19 VACCINATION AWARENESS AND PERCEPTION AMONG HEALTHCARE WORKERS IN A TERTIARY HOSPITAL IN THIRUVANANTHAPURAM DURING IT'S INITIAL PHASE
Authors: Raj. S. B Arathi , Bindu Sukumaran Anil , Jose Regi , Purandaran Vasanthamani Benny
Published: April 2023

Background: The Novel coronavirus infection spreads throughout the world and remains an international threat. The development of various
vaccines has paved the way for the prevention of Covid-19 infection. Healthcare workers are the most involved in the prevention of the pandemic.
So that in the initial phase of Covid-19 vaccination, Healthcare workers were given priority. This study was done to assess the awareness and
perception of covid-19 vaccination among healthcare workers in the initial phase of the covid-19 vaccination program. To assess the Objective:
awareness and perceptions regarding Covid-19 vaccination among healthcare workers at the initial phase of vaccination. Cross- Methods:
sectional study was conducted among the healthcare workers working in a Tertiary care Hospital in Thiruvananthapuram. Data was collected from
432 participants who came for vaccination using a semi-structured questionnaire. A Results: mong 432 study participants, 86.1% were aware of the
vaccine dosage and schedule but 13.9% do not know about it. Out of those who are aware 76.62% got information from the news & social media.
About 88.12% of participants have taken the vaccine to develop immunity. Among the participants, 40.45% had concern regarding the vaccine side
effects. 71.3% reported that they will continue to follow the Covid-19 preventive measures strictly, over after the vaccination. The Conclusion:
majority of the Healthcare workers were aware of Covid -19 vaccination. Even though vaccinated 13.9% were not aware of the vaccine dosage and
schedule. Healthcare workers should educate about the same. Also, raise awareness among those vaccinated individuals to follow strict preventive
measures for preventing the infection. Concerns regarding the Covid-19 vaccination among healthcare workers need to be addressed
ROLE OF P 53 AND KI-67 AS A PROGNOSTIC BIOMARKER OF UROTHELIAL CARCINOMA.
Authors: Patra Satotsna , Mittal Ruchi , Abinash Sahu Anubhav , Agarwal Sunil , Das Liza , Mohanty Raghumani
Published: April 2023

Introduction: Bladder cancers are common malignancies worldwide, and histological examination is the cornerstone of diagnosis and
management of these tumours. There exists huge interobserver variability in grading of urothelial carcinoma, furthermore supercial biopsies and
cautery effect also effect tumour staging. Pathological grading, staging and their correlation with molecular markers like p53 and Ki-67 might
better predict patient outcome and play signicant role in designing the management protocols of these patients. Thus, we aimed to study the role
of p 53 and Ki-67 as prognostic and diagnostic biomarkers of urothelial carcinoma in south east Indian population. This was a Methods:
prospective study that included 46 patients with Urothelial carcinoma of the urinary bladder. The histopathological evaluation of the tumor tissue
was performed to assess the grade and stage of the tumor and was further correlated with important demographic details and with
immunohistochemical expression of p 53 and Ki-67. The mean age was 55 and 65 years Results: for male and female patients respectively.
Haematuria was the most common presenting symptom. A total of 38 (74%) patients had high-grade tumors. p T2 stage disease was observed in
60% patients. High expression of p 53 expression was noted in 52% of total cases, of which 85% of cases had high grade morphology and 66%
were p T2 stage tumours. High expression of p 53 was also noted in 45% of p T1 tumors. Ki-67 showed high expression in 82.6 % of cases; 94% of
which were high-grade and 25% were low-grade cases. Although males have preponderance for Conclusion: afiction, but in our country, females
also show higher incidence of urothelial carcinoma as compared to published literature. In addition, patients in Indian population present with
higher stage disease. p 53 and Ki-67 are biomarkers of higher stage and grade disease, however additional factors also play a denite role in tumour
progression and thus in patient outcome
BIOFILM IN ORTHODONTICS: A REVIEW
Authors: Barman Dhritiman
Published: April 2023

The placement of xed orthodontic appliances creates retentive areas for the accumulation of biolm. The lodgment of biolm leads to various
gingival and periodontal diseases along with enamel demineralization, caries. The xed appliance hinders the mechanical removal of the biolm.
The deposition also depends on the materials used for manufacturing brackets and ligatures. The following review article discusses about the
biolm along with the measures for the maintenance of oral hygiene
“A PROSPECTIVE STUDY OF ADVANTAGES OF TRANS SPHENOID APPROACH FOR PITUITARY ADENOMAS OCCURRING AT GGH, KAKINADA”.
Authors: CH.V. Siva Kumar V. , Venkata Naga Swarna Yelleti , Bhavyasri Vadlamannati. , M Ujjwala , Balakrishnan Arjun
Published: April 2023

The most common pituitary tumour is adenoma, that arise from
epithelial cells of pituitary. They are most commonly benign.
Depending on size of the adenoma it is classied as micro
adenomas[<10mm] and macro adenomas [>10mm].The different
presenting types include: A) non-secretory/non-functional type, which
can be asymptomatic or have widespread consequences including
headache, vision problems, vomiting, etc.; and B) secretory/functional
type, which causes hormonal imbalance. Recently, the trans nasal
trans-sphenoidal endoscopic technique is used as a less invasive
procedure to resect pituitary tumours with minimal morbidity and
mortality . Imaging modalities play a role key role in surgery giving the
size, extent, and consistency of the tumour
A CASE REPORT OF ACUTE SUBDURAL HAEMATOMA DUE TO DENGUE HAEMORRHAGIC FEVER
Authors: Ravindra Suranse Shital , Yerandikar Aditya
Published: April 2023

A 18-year-old male was admitted with high-grade fever and severe headache since 5days. Dengue-specic IgM antibody was positive. History of
head trauma was absent. Investigations revealed haemoglobin 10.3 g/dl , haematocrit 29%, normal leukocyte count 9000/mm 3 , and platelet count
11,000. Headache was very severe that it was not relieved by analgesics . CT Brain was done for further evaluation. CT brain showed left fronto
parietal Acute Subdural Haematoma with midline shift .
ANAESTHETIC IMPLICATIONS OF NEUROPHYSIOLOGICAL MONITORING IN PAEDIATRIC PATIENTS UNDERGOING KYPHOSCOLIOSIS CORRECTION: A CASE SERIES
Authors: Shruti N Rathi , Abhay G Sancheti , Sarita S Swami
Published: April 2023

Kyphoscoliosis is a progressive disorder that requires to be corrected surgically before adolescence sets in. Intraoperative Neurophysiological
Monitoring (IONM) has emerged as a standard practice because it signicantly reduces neurological morbidity. Although much has been written
on IONM in adult spine surgery, very little has been published related to the neurological outcome in paediatric population with continuous IONM.
We report three patient with Paediatric kyphoscoliosis who underwent correction and had continuous IONM done over six months at a tertiary care
center. We recommend that effective use of IONM would involve a checklist to manage the changes in neurological signals and good teamwork of
anesthesiologist, surgeon, and neurophysiologist to respond to these changes
The EmoPain@Home Dataset: Capturing Pain Level and Activity Recognition for People with Chronic Pain in Their Homes
Authors: Olugbade Temitayo , Buono Raffaele , Potapov Kyrill , Bujorianu Alex , Williams Amanda , de Ossorno Garcia Santiago , Gold Nicolas , Holloway Catherine , Berthouze Nadia
Published: April 2023

Chronic pain is a prevalent condition where fear of movement and pain interferes with everyday functioning. Yet, there is no open body movement dataset for people with chronic pain in everyday settings. Our EmoPain@Home dataset addresses this with capture from people with and without chronic pain in their homes, while they performed their routine activities. The data includes labels for pain, worry, and movement confidence continuously recorded for activity instances for the people with chronic pain. We explored two-level pain detection based on this dataset and obtained 0.62 mean F1 score. However, extension of the dataset led to deterioration in performance confirming high variability in pain expressions for real world settings. We investigated activity recognition for this setting as a first step in exploring the use of the activity label as contextual information for improving pain level classification performance. We obtained mean F1 score of 0.43 for 9 activity types, highlighting its feasibility. Further exploration, however, showed that data from healthy people cannot be easily leveraged for improving performance because worry and low confidence alter activity strategies for people with chronic pain. Our dataset and findings lay critical groundwork for automatic assessment of pain experience and behaviour in the wild. 
Shape Sensing for Continuum Robotics using Optoelectronic Sensors with Convex Reflectors
Authors: Osman Dalia , Du Xinli , Minton Timothy , Noh Yohan
Published: April 2023

Three-dimensional shape sensing in soft and continuum robotics is a crucial aspect for stable actuation and control in fields such as Minimally Invasive surgery, as the estimation of complex curvatures while using continuum robotic tools is required to manipulate through fragile paths. This challenge has been addressed using a range of different sensing techniques, for example, FBG technology, IMU networks or stretch sensors. Previously, an optics-based method, using optoelectronic sensors was explored, offering a simple and cost-effective solution for shape sensing in a flexible tendon-actuated manipulator in two orientations. This was based on proximity-modulated angle estimation and has been the basis for the shape-sensing method addressed in this paper. The improved and miniaturised technique demonstrated in this paper is based on the use of a spherically shaped reflector with optoelectronic sensors integrated into a tendon actuated robotic manipulator. Upgraded sensing capability is achieved using optimisation of the spherical reflector shape in terms of sensor range and resolution, and improved calibration is achieved through the integration of spherical bearings for friction-free motion. Shape estimation is achieved in two orientations upon calibration of sensors, with a maximum Root Mean Square Error (RMS) of 3.37°
Performance Analysis of Gasoline Engine with Different Ethanol Blends
Authors: Kumar Venktesh
Published: April 2023

The rapidly growing consumption of petroleum-based fuels causes the government to expend a significant source of foreign currency on oil imports, which impacts the trade deficit in the government's current account. The purpose of the feasibility is to see how unleaded fuel blends impact the performance of an unmodified engine operating on numerous blends. This testing was performed using a four-stroke, single-cylinder, water-cooled multi-fuel engine (Computer controlled variable compression ratio multi-fuel injection, kirloskar type engine) with a carburetor fuel injection system. Multiple parameters such as brake thermal efficiency, brake power, engine torque, brake mean effective pressure, and brake specific fuel consumption were assessed throughout the benchmarks.Regular unleaded blends with multiple fuel proportions have been used in these investigations. Six ethanol blend fuels were tested and their physical and chemical characteristics were analyzed, with 90 octane numbers achieved using unleaded fuel at E0, E5, E10, E20, and E40, along with variations in compression ratio. Research experiments were carried out at various different pressure ratios of 10.5:1 and 12:1, with engine speed calibrated to 1500 rpm. The findings demonstrate that blending unleaded fuel with a fraction of ethanol enhances the efficiency of the engine, such as brake power, torque, and brake thermal efficiencies and fuel consumption, thereby reducing brake specific fuel consumption. While compared to other proportions, the E20 (Ethanol 20%) ratio delivered the best brake power versus speed. 
Virtual Reality Training of Social Skills in Autism Spectrum Disorder: An Examination of Acceptability, Usability, User Experience, Social Skills, and Executive Functions.
Authors: Kourtesis Panagiotis , Kouklari Evangelia-Chrysanthi , Roussos Petros , Mantas Vasileios , Papanikolaou Katerina , Skaloumbakas Christos , Pehlivanidis Artemios
Published: April 2023

Poor social skills in autism spectrum disorder (ASD) are associated with reduced independence in daily life. Current interventions for improving the social skills of individuals with ASD fail to represent the complexity of real-life social settings and situations. Virtual reality (VR) may facilitate social skills training in social environments and situations proximal to real life, however, more research is needed for elucidating aspects such as the acceptability, usability, and user experience of VR systems in ASD. Twenty-five participants with ASD attended a neuropsychological evaluation and three sessions of VR social skills training, incorporating 5 social scenarios with three difficulty levels for each. Participants reported high acceptability, system usability, and user experience. Significant correlations were observed between performance in social scenarios, self-reports, and executive functions. Working memory and planning ability were significant predictors of functionality level in ASD and the VR system’s perceived usability respectively. Yet, performance in social scenarios was the best predictor of usability, acceptability, and functionality level in ASD. Planning ability substantially predicted performance in social scenarios, postulating an implication in social skills. Immersive VR social skills training appears effective in individuals with ASD, yet an error-less approach, which is adaptive to the individual’s needs, should be preferred. 
SPICE Simulation of Quantum Transport in Al2O3/HfO2-Based Antifuse Memory Cells
Authors: Miranda Enrique , Aguirre Fernando , Saludes Mercedes , Gonzalez Mireia B. , campabadal Francesca , Suñé Jordi
Published: April 2023

 This letter reports a compact SPICE model for the electron transport characteristics of Al2O3/HfO2-based nanolaminates for their use in multilevel one-time programmable (M-OTP) memories. The model comprises three simulation blocks corresponding to the electrical stimulus applied to the device, the equivalent circuit of the memory cell, and the events generator associated with the dielectric breakdown of the insulating layer. For a clear assessment of the quantum effects occurring in these structures, constant voltage stress was used as the primary electrical stimulus. The antifuse (AF) cell is represented by a combination of series and parallel resistances that account for the formation of filamentary conducting paths with quantum properties across the structure. The arrival of successive breakdown events is simulated using a power-law nonhomogeneous Poisson process. 
Does Artificial Intelligence help Journalists: A Boon or Bane?
Authors: Dhiman Dr. Bharat
Published: April 2023

Artificial Intelligence (AI) is used in our day-to-day life. AI for journalism is a reality. Just like other vital aspects of our life, AI has also entered the world of journalism. Many reputed news organizations have adopted AI in journalism to perform various newsroom tasks. In today’s digital world, several technologies are powering journalism. One such technology that is transforming the journalism field is artificial intelligence. Accuracy is a core value of journalism. With AI and machine learning systems, there’s a statistical element of uncertainty which means it’s impossible to guarantee 100 percent accuracy. AI tools such as OpenAI’s ChatGPT, Microsoft’s Bing chatbot, and Google’s Bard have been subject to debate now. AI tools have the potential to assist in a variety of tasks, such as scraping PDF files, writing code, and translating languages. AI can be a helpful tool for journalism students and media researchers. A main concern among computational journalists is that AI sometimes hallucinates data. This review paper highlights how artificial intelligence can help journalists.
A study of Impulsiveness in Relation to Environmental Ethics of Secondary School Students
Authors: Kaur Kiranjit , Goyal Madhavi
Published: April 2023

The present research aims to examine the impulsiveness in relation to the environmental ethics of secondary school students. The currentstudy targeted a sample of 100 secondary school students of Chandigarh. Descriptive survey was done for the collection of data. The datawas analyzed statistically by using mean, standard deviation, t-test and Pearson’s coefficient of correlation (r). The study's findings revealed nosignificant relationship exists between impulsiveness and environmental ethics of secondary school students. The study recommended thatstakeholders in education needed to identify and understand the psychological needs of adolescents. The study recommends future researchon how impulsiveness varies and test if impulsiveness can be improved by implementing various workshops and counseling.
Impact of Non-academic Responsibilities of Teachers on Teaching Quality
Authors: Kulal Abhinandan , N Abhishek , . Meghashree , Kanchan Swarn G.
Published: April 2023

Teaching quality in an education system becomes the foundation and roadmap to the development of young people and the country at large. If the quality of education declines, the country's productivity also declines. Whatever the type of education institutions running in the country must emphasize on improving the quality of education they are intended to provide. Nowadays, it can be noticed that many education institutions are becoming commercial and mainly focusing on getting grades, certifications, rankings and recognitions. The present study aims to examine the impact of non-academic responsibilities on the quality of teaching. For this purpose, the study adopted a descriptive research design to analyze the collected data from the teachers teaching in higher education. This study observed that non-academic responsibilities are significantly influencing on teaching quality in India. Thus, higher education institutions and regulators should work together to bring policies, strategies and methods to balance academic and non-academic responsibilities without compromising teaching quality. If this is the reality, the students' competencies for their survival will be enhanced and in turn, the overall productivity of young people will also go up for the long run.
An Analysis of the Usage of Social Networking Sites by Prospective Teachers during Pandemic Period
Authors: Lal Shilpi , Gupta Satyendra
Published: April 2023

Social networking sites (SNSs) are defined as web-based services that allow individuals to construct a profile and share connections with acertain list of other users. Their phenomenal features like information and communication, entertainment and immediate interaction witheach other popularized them worldwide. The recent perilous COVID-19 pandemic has brought a new normal to the forefront in all spheres oflife in general and education in specific. This pandemic raised the demand for online education modes. The existing SNSs successfully fulfilledthat immediate demand. To carry out the online teaching-learning process without disruption, the Education sector had to adopt these SNSsimmediately. This usage of the SNSs popularised them among the students and they started using them for other than educational purposes.In the present study, researchers analyzed prospective teachers' usage of social networking sites during the pandemic period. The analysis ofthe basic usage pattern of SNSs in the present study reveals that the prospective teachers at large started using them on daily basis and evenmultiple times a day during the pandemic. While analyzing the affective experience of using SNSs, the prospective teachers' researchers foundthat most users were satisfied with these social media sites.
Birth Outcomes and IGF2 Methylation in P3 Promoter Region in Tibetan and Han Chinese Maternal-newborn Pairs in Hypo-baric Hypoxia High-altitude Area
Authors: Jian Wenxiu , Sun Pin , Wang Xuejun , Wang Pinhua , Zhaxi Jiangzuo , Zhang Yangrui , Wang Shulin , Zhao Dexiong , Fan Yuemei , Wang Liehong , Peng Wen
Published: April 2023

Background: The relationship between Insulin-like growth factor 2 (IGF2) methylation in the P3 promoter region and birth outcomes in a hypobaric-hypoxia environment has never been investigated. This study examined the association and compared birth outcomes and IGF2 methylation in this region by ethnicity and altitude.
Methods: Four hundred and six (406) mother and newborn pairs in the Tibetan Plateau were enrolled in a birth cohort study. Data were collected through interviews using structural questionnaires or extracted from medical records. Pyrosequencing was performed for IGF2 methylation in the P3 promoter region in maternal peripheral and umbilical cord blood. Birth outcomes and IGF2 methylation were compared among three groups: Han in high altitude (HHA, n=164, 2000-3500m), Tibetan in high altitude (THA, n=42, 2000-3500m), and Tibetan in ultra-high altitude (TUHA, n=200, 3500m and higher).
Results: TUHA seemed to have a higher prevalence of macrosomia (7.5%) than both THA (0.0.%) and HHA (2.4%) and a lower IGF2 methylation level in maternal blood than THA (P=0.008). No difference in the IGF2 methylation levels was found between THA and HHA. The IGF2 methylation levels in maternal peripheral blood were associated with a reduced risk of macrosomia (RR= 0.726, 95% CL [0.528,0.998], P=0.049) among all mother and newborn pairs.
Conclusions: Increased altitude appears to be associated with decreased maternal IGF2 methylation levels in the P3 promoter region, and maternal IGF2 methylation levels in this region was associated with reduced risk of macrosomia in newborns in the hypobaric hypoxic Tibetan Plateau environment.
Keywords
Macrosomia; IGF2; DNA methylation; high altitude; Tibet Plateau
A Study to Assess the Maternal Factors Leading to Low Birth Weight Babies in Selected Hospitals of Pune-India
Authors: Mathew Shaila , Karim Kafia Hashim
Published: April 2023

Background: The birth weight of an infant is the single most important determinate of its chances of the survival, health growth and development.
Objectives: Assessment of maternal factors leading to low birth weight babies and Associate it with some demographic variable of the babies.
Methodology: Non-experimental exploratory survey research was conducted in Jun 20th  to Dec 31st 2011 in India. A Non-probability convenient sample consists of 100 postnatal mothers who delivered low birth weight babies were selected from Pune Hospitals. The tool used for data collection is a structured questionnaire consisted from two sections: 1- Maternal factors and 2- Demographic variables. Content validity of the tools determined by a panel of experts. Reliability was determined by rational equivalence test. Both descriptive and inferential statistics were used for data analysis.
Results: The results of current study reveals that there were high significant association between medicines taken during pregnancy with gestational age, a significant association between maternal factors like weight gain during pregnancy with gestational age, a significant association between maternal factors like iron and folic acid during pregnancy with gestational age. There is no significant association among other factors.
Conclusion: Researcher concluded that maternal factors (Personal, Biological, Nutritional, History of disease, Psychological and Social factors) can affect the weight of the babies.
Recommendations: Further studies need to be conducted among antenatal and postnatal women.
Serum Fetuin-A, A New Potential Biomarker for Diagnosis of IHD in Menopausal Women.
Authors: AL-Dejaly Arshad N. , Emad Mohammed , Khudhair Safaa Ali
Published: April 2023

Background: The role of inflammation in atherogenesis would suggest, a great deal of work looking for inflammatory markers that are risk factors for IHD. The most extensively examined markers are fibrinogen, C-reactive protein, IL-6, homocysteine, and fetuin-A.
Objective: The present study is focusing on role of biomarker fetuin-A in the diagnosis of IHD in menopausal female.
Methodology: This study involved 76 menopause women suffering of IHD (42 patients with AMI and 34 with angina) and 20 healthy menopause women as control. Patients were divided into subgroups according to the presence of DM and hypertension. Serum Fetuin-A level is estimated in each group.
Results: There is significant reduction in serum fetuin-A levels in menopausal women with IHD. Diabetes mellitus and hypertension associated with significant decrease in serum fetuin-A levels in menopausal women with IHD.
Conclusion: Serum fetuin-A can be used as biomarker for diagnosis of angina and AMI in menopausal women. Both DM and hypertension have detrimental effect on serum fetuin-A levels.
Multimodality Echocardiographic Imaging for a Novel Transcatheter Native Mitral Valve Replacement Procedure
Authors: Galzerano Domenico , Alamro Bandar , Moreo Antonella , Bossone Edoardo , Vriz Olga , Alenazy Ali , Alshehri Ahmed , Al Amri Mohammed , Alhamshari Ahmad , Al Sergani Hani
Published: April 2023

Transcatheter native mitral valve replacement (TMVR) is a novel procedure that has the potential to overcome some of the current limitations associated with the transcatheter edge-to-edge mitral valve (MV) repair technique. The aim of this study was to describe the key steps in periprocedural echocardiographic guidance of TMVR with the Tendyne system, emphasizing potential caveats and areas of difficulty. The imaging pathway can be schematized in four fundamental steps: baseline evaluation of mitral regurgitation (MR), preprocedural screening and planning, intraprocedural guidance, and follow-up. Baseline evaluation of MR in TMVR includes the guidelines-recommended imaging pathway of MR assessment. A dedicated preprocedure cardiac multimodality imaging screening and planning for TMVR is able to determine patient eligibility according to the anatomic characteristics and measurements, provide information for appropriate valve sizing, and detect features that can predispose to potential hazard or complications. Cardiac computed tomography and two-dimensional (2D) and three-dimensional (3D) transesophageal echocardiography (TEE) are the main actors in this phase. The road map for intraprocedural TMVR guidance includes the following: (1) apical access assessment: 2D TEE assessment of the site for optimal left ventricular apical access as planned by the preprocedural computed tomography; (2) support for catheter and sheath localization, trajectory, and positioning; and (3) valve positioning and radial orientation. Thereafter, the prosthesis is withdrawn toward the left ventricle and deployed intra-annularly. Post-deployment includes assessment for correct clocking and hemodynamics, perivalvular leakage, and left ventricular outflow tract obstruction. Two-dimensional and 3D TEE and fluoroscopy provide intraprocedural guidance. The follow-up of the Tendyne device includes the guidelines-recommended imaging pathway of bioprosthesis. Knowledge of multimodality imaging use is key for the interventional imagers and crucial in the success of the procedure.
KLASIFIKASI RISIKO KEMATIAN PASIEN BERDASARKAN PENYAKIT PENYERTA DAN USIA PASIEN MENGGUNAKAN METODE C4.5
Authors: Fery bayu aji  , Fajri Rakhmat Umbara  , Fatan  Kasyidi
Published: April 2023

Tingginya angka kematian pada orang yang menderita penyakit tertentu, maka kami melakukan penelitian ini. Untuk mengetahui pasien dengan risiko kematian tinggi atau rendah. Maka dilakukannya klasifikasi risiko kematian pasien berdasarkan usia dan penyakit penyerta pasien dengan menggunakan decision tree algoritma c4.5. Algoritma C4.5 digunakan untuk menemukan pola menentukan data tersebut masuk kedalam kelas mana dengan  menggunakan data latih dan data uji digunakan untuk evaluasi. Hasil pengujian akurasi menggunakan Confusion Matrix dengan pembagian data, data latih 70% data data uji 30% mengghasilkan 72% sementara dengan pembagian data, data latih 80% data data uji 20% menghasilkan akurasi sebesar 70%. Dengan menggunakan model pembagian data, data latih 70% data data uji 30% lebih unggul dibanding data latih 80% data data uji 20%. Semantara akurasi yang dihasilkan dengan metode pemotongan pohon atau pruning dapat menurunkan akurasi dengan hasil akurasi sebesar 66%. Dan berdasarkan pohon keputusan yang dihasilkan tanpa pruning menghasilkan kedalaman pohon sebanyak 11 level.
To Study the Impact of Socioeconomic Status on Bone Mineral Density Among South Indian Women
Authors: Gladia R  , T. Ashrin  , Paul Jibi
Published: April 2023

Background of the study: Osteoporosis is a worldwide disease characterized by reduction of bone mass and alteration of bone architecture resulting in increased bone fragility and increased fracture risk. It mainly affects premenopausal and postmenopausal women. In Indian women prevalence of osteoporosis mainly because of low calcium intake, vitamin D deficiency, sex in equality, early menopause, genetic predisposition, lack of diagnostic facilities and poor knowledge on bone health. The aim of the study is to find out the impact of socioeconomic status on bone mineral density in south Indian women. Methodology: It is an observational study and non-experimental type. 100 subjects taken for this study. The age group between 35-60 years and women only selected for this study. The study duration is 2 months. The material used are paper and pen. Modified BG prasad socioeconomic classification. Selfadministrated socioeconomic status questionnaire. The participants were given self-administered socioeconomic questionnaire and classified according to their socioeconomic status based on Modified BG Prasad socioeconomic classification to find the (SES) of an individual. The mineral density was corelated using Quantitative calcaneal ultrasound and recorded. The recorded data were analysed and interpreted. Result: Quantitative calcaneal ultrasound T score bone mineral density has shown significantly lower mean value -2.66 (osteoporotic) and as a whole,5% osteoporosis in subjects with lower economic status. Conclusion: The study concluded that low SES is risk for Osteoporosis. So, the awareness among people is essential for good healthy lifestyles and prevent the dangers of osteoporosis.
Effects of Land Based Exercise Protocol in the Management of Hindlimb OA in White Gaint Rabbit
Authors: Nithyanisha R  , Thiyageeswaran  , Yashin B Mohammed
Published: April 2023

Back ground of the study: Osteoarthritis (OA) is one of the most commonly occurring forms of arthritis in the world today. Hind limb weakness is caused by a disorder such as a break, strain, degenerative damage or other physical process, this can result in temporary or permanent inability to use the back legs. Physical therapy techniques to increase function and mobility of joints from, injury, surgery, degenerative diseases, age related diseases and obesity. Methods: This is an experimental study conducted at M. K. Vet. Clinic, Villupuram for a duration of 3 sessions per week for about 4 weeks (1 month) for a sample size of 15 subjects. Random sampling method used to allocate the samples in two groups. White Giant Rabbits with Age group between 3-4years and CANCRS (composite pain score of 2-4) were included for this study. age group between 4-6 years. White Giant Rabbit-breeds irrespective of gender with duly vaccinated. Rabbits’ intervention included land-based exercises. Outcome measures of the study was cancrs. Result: On comparing the mean values of Group A & Group B on Multidimensional Composite Pain Scale score, it shows a significant decrease in the post test mean values in both groups, but Group A shows mean difference of 5.90 which has the more effective than Group B with mean difference of 3.90 at P ≤ 0.05. onclusion: The study concluded that land-based exercise protocol is more effective on management of hind limb OA in White Giant Rabbits.
COVID-19 AND ITS IMPACT ON MSMES IN KARNATAKA : A STUDY WITH VIJAYAPURA DISTRICT
Authors: Dr.Suresha K.P
Published: April 2023

In modern era, entrepreneurship is one of the main pathways to achieve gender equality and women’s economic empowerment- as set out in Sustainable Development Goal (SDG), which can in turn have a multiplier effect on family well-being, poverty reduction and sustainable economic growth. MSMEs are central - not only in promoting inclusive and sustainable economic growth, employment, and decent work for all; MSMEs also promote sustainable industrialization and foster innovation and can help reduce income inequalities if they receive support to provide good quality jobs. Finally, they can support achieving gender equality and women’s empowerment through female entrepreneurship. While the rates of infection and death as a result of this pandemic appear to be higher for men than women so far, it is envisaged that women and girls will bear a disproportionate burden of the primary, concurrent, secondary and tertiary impacts of the disease, in terms of economic, social and health risks.
ATTITUDE TO THE WORK OF WILLIAM SHAKESPEARE IN WORLD LITERARY STUDIES
Authors: Namozova Saodat Baxtiyorovna
Published: April 2023

Various poetic features of William Shakespeares work, his scope of creative influence, in particular, a number of problems, such as the scope of creative influence, have not lost their relevance to this day. To study and draw reasonable conclusions about the concepts of Shakespearean tradition, as well as Shakespeareanism from the perspective of emerging and modern studies, especially from the perspective of certain views, creative influence.
KEY WORDS: Shakespearean tradition, creative influence, poetic features, creative, world literature, dramaturgy
The Correlation between Critical Thinking Skills and Argumentative Writing Skills in Moroccan Higher Education
Authors: Beniche Mounir
Published: April 2023

The aim of this study is to  examine  the correlation between two major variables which are critical thinking skills and argumentative writing skills in Moroccan higher education. The participants were Semester 4 and Semester 6 students (English department, Faculty of Languages, Letters and Arts Ibn Tofail Universty, Kenitra). 100 students participated in the study. 50 students from semester 4 and 50 students from semester 6. The study resorted to the correlation design for measuring the degree of association between two variables adopting the statistical method of correlation analysis. Hence , a critical thinking test (AssessmentDay Practice Test Experts, 2018) was displayed to test students’ critical thinking skills. Then, the students were asked to write an argumentative essay about social media  and everday communication . For the  analysis of  the collected data, the study used  SPSS software (Statistical Package for the Social Sciences, version 23). Pearson’s correlation coefficient was applied to examine the significant relationship between critical thinking skills and argumentative writing. The study result showed  that correlation coefficient of critical thinking test and argumentative essay of S4 students is 0. 683 and of of S6 is 0. 781 which implies  that the two tests are positively correlated and the correlation between critical thinking and argumentative writing  is positive and very significant.
THE DEATH OF THE TSESAREVICH AND THE RISE OF A NEW SUCCESSOR: THE DIARY OF GRAND DUKE MICHAEL ALEXANDROVICH, JUNE 28 - AUGUST 9, 1899
Authors: SOFJINA MARINA
Published: April 2023

For the first time, a fragment of the diary of Grand Duke Michael Alexandrovich for 1899 is published. The records describe the death and burial of his brother, the Successor Tsesarevich George Alexandrovich, as well as the first weeks of Grand Duke Michael Alexandrovich’s stay in the status of heir to the throne. The study sessions of the Grand Duke, his official activities and leisure, family environment are characterized. Diary entries indicate that the new status of the Successor at that time did not lead to changes in the daily life and occupations of Grand Duke Michael Alexandrovich.
LITERACY RATE IN PERM GOVERNORATE ON THE DATA FROM THE ALL-RUSSIAN POPULATION CENSUS OF 1920
Authors: SHUVALOVA YULIYA
Published: April 2023

The article considers the level of literacy of the inhabitants of the Perm governorate in 1920. The study is based on the materials of the All-Russian Population Census of 1920. The correlation of literate and illiterate adults aged 20-29, 30-39 and 40-49 is analyzed. For ease of comparison, the number of literate adults is given in absolute terms and in percentage terms in relation to the total number of a particular gender and age group. The calculated data are systematized in the following tables. The general patterns in the distribution of literates are revealed. Residents of cities and factory settlements had more opportunities in the field of education in the first quarter of the twentieth century. The gender identity of illiterates aged 25 to 49 was typical for traditional society: women had fewer opportunities to get an education. Educational opportunities of school-age children did not depend on gender characteristics. The level of literacy was more significant in the age group from 20 to 29 years old. There were more literate women of 20-29 years old in cities, towns and villages in absolute numbers than men of the same age. This indicates a gradual change in attitudes to education in general and to women's education in particular, which was took place in the Russian provinces in the early XX century.
ON THE CULTURAL-ETHIC CATEGORIES TRANSFORMATION IN EUROPE OF THE XIX CENTURY: SEARCH FOR THE BASIC FOUNDATIONS
Authors: SEMUKHINA ELENA
Published: April 2023

The article aims at discussing the XIX century’s European studies which influenced the new ethically-themed performance, viewed as the source of the main meaningful (or subject-to-subject) cultural categories. Social and scientific changes, which led to the “cultural upheaval”, made the scientists consider the value system newly and define the existence of the dynamic cultural-ethic elements as a system. Further this approach provided the basis for the division of the cultural categories into fundamental and meaningful. The vectors of ethic norms’ transformation are also under discussion, i.e. the development of philosophical ideas of the following researchers A. Schopenhauer, F. Nietzsche, Ch. Darwin, A. Bergson: voluntaristic (built on the philosophy of the will), evolutionist (based on the Ch. Darwin’s theory of biological evolution) and vital (designed on the metaphysics of Bergson’s Elan Vital). Viewed as a whole, both “philosophy of living” and Ch. Darwin’s theory of the origin of species seem to ground cultural categories of a moral and ethical value. Thanks to them, life turned out to be not only of irrational creative philosophical principle but also of the ultimate value; while the concept struggle for existence moved to Biology. Life as an ultimate value acknowledgment did not mean the full refusal from the morality with the social degradation, it was only associated with relativization of traditional (Christian, primarily) values. This acknowledgment did not involve the recognition of the human being’s unlimited selfishness which in practice had to give way to the “instinct” of solidarity found in animality.
Negocios y Administración
Authors: Moscoso Paucarchuco Ketty Marilú
Published: April 2023

El presente libro de carácter académico se titula Negocios y Administración, es una selección de artículos publicados en el periódico digital unahALDÍA, iniciativa de la Universidad Nacional Autónoma de Huanta, Ayacucho, institución que me permite desenvolver en espacios de investigación, extensión universitaria y otros. Tiene el objetivo de dar a conocer una serie de metodologías para el desarrollo de una administración eficaz y eficiente, delimita conceptos operacionales para la buena toma de decisiones, valora la importancia del talento humano en las organizaciones. Por los temas actuales y herramientas modernas de gestión, se asevera que es un material de uso continuo, permite la fácil aplicación de técnicas como diagrama tortuga, matriz 3M, mapa de empatía, metodología 5W2H, empowerment, downsizing, casa de la calidad, 5S, 9S, modelo KANO, gestión OKR, elevator pitch, storytelling, flor de servicios, entre otros. Desarrolla también fortalecimiento del marketing digital, mostrando la forma correcta para definir el perfil del consumidor, desarrollar inteligencia de mercado, crear marca personal y marca colectiva. En la fase de control se preocupa por la auditoría, mostrando Sistemas de Control Interno, como el modelo COSO, motivando a generar Indicadores de Gestión (KPI's), los que permiten un avance significativo en la producción de bienes y prestación de servicios con márgenes por encima de los aceptables de rentabilidad. Como parte del rol de la administración ante la sociedad, enmarca la importancia de la inclusión financiera, valor compartido, incubadora de empresas para el desarrollo sostenible, etc. motivando la generación de negocios con responsabilidad social empresarial y por supuesto sostenibles. Curso la invitación a su lectura, a espera de las críticas constructivas, diálogo y debate.
A Family as a Civil-Law Community (On the Examples of Bankruptcy Cases)
Authors:   National Research University “Higher School of Economics”, Shevchenko Ilia M.
Published: April 2023

The author asserts, that a family is a civil-law community and by some characteristics it is close to a legal entity. It is stated in the article, that if the common joint ownership concept is brought to its logical result, the claims of an ex-spouse shall be subordinated to claims of external creditors during the division of common property. The author also supports the presumption of community of debts.