bluuebunny/crossref_metadata_2025 huggingface dataset:
A new day for Hulk Hogan: Celebrity selves and racial diversity in contemporary professional wrestling
Authors: Koh Wilson
Published: August 2021

This paper considers contemporary World Wrestling Entertainment’s new racial politics in the light of Hulk Hogan’s 2015 erasure from the Federation after a leaked racist sex tape rant, and the African-American wrestlers The New Day’s rise to fame during the same period. This paper locates WWE’s actions as responses in line with a domestic media marketplace where the rhetoric of racial diversity is fetishised. In doing so, this paper combines literature on corporate social responsibility, race, and the performativity of the self in contemporary celebrity culture. This paper reads World Wrestling Entertainment’s actions as strategies through which the Federation’s corporate social responsibility is spectacularly performed, allowing it to grow and survive in the streaming video era.
Technology of optimization: An emerging configuration of productivity among professional software employees
Authors: Ciccone Vanessa
Published: August 2021

In this article, I draw from several months of fieldwork from 2019 to assess professional subjectivity in the software industry of Canada. I assess employees’ constructions of and feelings about their own productivity. I argue that the ways in which subjects understand and feel about their productivity says a great deal about how power is ‘willfully’ negotiated within everyday professional tech settings of neoliberal societies. My findings suggest that optimization is emerging as a technology of self among the individuals I studied, and bringing political consequences. In the first section of the article, I provide a brief overview of the productivity imperative’s cultural trajectory, and show its relation to optimization. Then, in the empirical analysis and discussion, I outline that the technology of optimization involves a discourse around bringing one’s best to public and private realms, offering a specific set of moral ideals. I then show that another facet of this technology of self is centered on willfully entangling public and private life. Finally, I theorize subjects’ reported feelings about their own productivity, assessing how the technology of optimization relates to a politics of privilege. With this study, I seek to make a contribution to the relation between the culture of productivity and professional subjectivity in the software industry, in an effort to expose how power is negotiated at the level of the self in an increasingly influential sector.
Home in question: Uncovering meanings, desires and dilemmas of non-home
Authors: Boccagni Paolo , Miranda Nieto Alejandro
Published: August 2021

What is the opposite of home? Is it necessarily something ‘negative’? Similar questions, far from having a self-evident answer, make for a fruitful entry point for research into the social experience of home. Central to this article is a novel conceptualization of non-home, against the background of the pre-existing criticisms of the normative, romanticized and depoliticized understandings of home. This article draws from fieldwork on the everyday dwelling experience of migrants and asylum seekers to illustrate the volitional dimension of non-home. Not attaching a sense of home to a dwelling place or set of relationships is not merely a consequence of poor housing conditions. It may also involve an active choice – at least at some points of the life course, in certain household conditions. In this sense, non-home is more than a matter of absence, dispossession, reconfiguration or implosion of home. In questioning the normative view of home as inherently positive and desirable, this conceptualization highlights the reciprocal interaction between home and non-home as mutually interdependent constructs.
Climate change: An increase in norms for inclusion predicts greater fit and commitment for women in STEM
Authors: Hall William , Schmader Toni , Inness Michelle , Croft Elizabeth
Published: August 2021

In male-dominated STEM fields, workplace culture is often cited as a factor for women’s attrition. In the present research, we used longitudinal field data to examine how changes in the perceived normative support for gender-inclusive policies and practices over 6 months relate to changes in women’s and men’s experiences of fit and commitment to their organization. Longitudinal analyses of survey data from a sample of 181 engineers revealed that increased perceptions of support for gender-inclusive policies and practices predicted increased organizational commitment only among women, an effect that was mediated by an increase in organizational value fit. Additional analyses suggest that perceptions of change in normative attitudes toward inclusive policies were more predictive of women’s organizational commitment than the awareness that the policies were in place or that one has personally benefitted from them. The implications of an inclusive workplace culture for supporting women’s retention in STEM are discussed.
Experimental investigation of wind loads on wind turbine blade under various turbulent flows
Authors: Li Yi , Song Qian , Li Qiu-Sheng , Wang Di-Ling , Wu Xiao-Peng
Published: August 2021

For investigation of the effects of turbulence intensity (TI) on the wind loads on wind turbine blade, a 1:20 scaled model of a typical 3D wind turbine blade is designed and used for the pressure measurement test in a wind tunnel. Five uniform flows with different turbulence intensities are simulated in the wind tunnel test. The mean and root-mean-square (RMS) wind pressure coefficients, base moment coefficients, and their power spectral densities are presented and discussed in detail. Combined with the dynamic properties of the blade structure, wind-induced displacements at the tip of the blade are calculated by the random vibration theory. The results show that the increasing of TI amplifies the aerodynamic loads on the blade in terms of RMS wind pressure coefficients and RMS bending moment coefficients. Large wind-induced displacement of the wind turbine blade may be stimulated by high TI even under the feathering condition. This article aims to further the understanding of wind loads on wind turbine blades and provide useful information for the wind-resistant design of wind farms established in regions with high turbulence levels.
Toward a machine learning model for a primary diagnosis of Guillain-Barré syndrome subtypes
Authors: Alarcón-Narváez Daniel , Hernández-Torruco José , Hernández-Ocaña Betania , Chávez-Bosquez Oscar , Marchi Jerusa , Méndez-Castillo Juan José
Published: August 2021

Guillain-Barré Syndrome (GBS) is a neurological disorder affecting people of any age and sex, mainly damaging the peripheral nervous system. GBS is divided into several subtypes, in which only four are the most common, demanding different treatments. Identifying the subtype is an expensive and time-consuming task. Early GBS detection is crucial to save the patient’s life and not aggravate the disease. This work aims to provide a primary screening tool for GBS subtypes fast and efficiently without complementary invasive methods, based only on clinical variables prospected in consultation, taken from clinical history, and based on risk factors. We conducted experiments with four classifiers with different approaches, five different filters for feature selection, six wrappers, and One versus All (OvA) classification. For the experiments, we used a data set that includes 129 records of Mexican patients and 26 clinical representative variables. Random Forest filter obtained the best results in each classifier for the diagnosis of the four subtypes, in the same way, this filter with the SVM classifier achieved the best result (0.6840). OvA with SVM classifier reached a balanced accuracy of 0.8884 for the Miller-Fisher (MF) subtype.
Felonious line-of-duty officer deaths (1995–2015): The impact of tenure and age revisited
Authors: Tucker-Gail Kasey , Eckerley Andrew , Selman Donna L , Lilley David , Stewart Megan C
Published: August 2021

The purpose of this article was to reassess patterns previously identified in the Federal Bureau of Investigation’s Law Enforcement Officers Killed and Assaulted (LEOKA) data, expanding the time frame from 5 years to 20 years, for application within law enforcement when considering training needs over the life cycle of an officer's career. Consistent with the findings of the earlier analysis, this study identifies two prevalent patterns: the age range with the highest frequency of death was 30–39, and the years of experience with the highest frequency of death was 0–4. In fact, the analysis indicates an even stronger pattern of the deadly combination of age and tenure. Implications of the study include the need for larger scale data collection on the national population of officers, detailed information on transfers and time of service overall (as opposed to time in service at current department), and evaluations of current training programs and practices regarding de-escalation and the use of force as well as self-defense and situational awareness.
Health-related fake news on social media platforms: A systematic literature review
Authors: Melchior Cristiane , Oliveira Mírian
Published: August 2021

This review aims to (a) investigate the characteristics of both the research community and the published research on health-related fake news on social media platforms, and (b) identify the challenges and provide recommendations for future research on the subject. We reviewed 69 journal articles found in the main academic databases up to April 2021. The studies extracted data mainly from Twitter, YouTube, and Facebook. Most articles aimed to investigate the public’s reaction to fake health information, concluding that health agencies and professionals should increase their online presence. The articles also suggest that future work should aim to improve the quality of health information on social media platforms, develop new tools and strategies to combat fake news sharing, and study the credibility of health information. Nonetheless, those in control of the platforms are the only ones which can take effective measures to ensure that their users receive reliable information.
Effects of stroke on spark-ignition combustion with gasoline and methanol
Authors: Wouters Christian , Burkardt Patrick , Fischer Marcus , Blomberg Michael , Pischinger Stefan
Published: August 2021

Besides electrification of the powertrain, new synthetic alternative fuels with the potential to be produced from renewable sources come into focus. Methanol is the most elementary liquid synthetic fuel and no novelty for use in internal combustion engines. This article presents pathways to achieve high efficiency spark-ignition methanol combustion on a direct injection spark-ignition single-cylinder research engine with two different stroke-to-bore ratios (1.2 and 1.5) and a constant bore. In addition, two compression ratios (CRs) were investigated on each setup: CR = 10.8 using RON95 E10 gasoline fuel and a higher CR = 15 using neat methanol. In contrast to previous studies of stroke-to-bore ratio influences on SI combustion, this article aims at demonstrating how the advantages of a high stroke-to-bore ratio can be exploited by combining a long-stroke engine with increased compression ratios and methanol. The increased stroke enhances the tumble motion due to a higher piston speed and a larger compression volume which improves the mixture homogenization and combustion velocity. Moreover, the lower surface/volume ratio results in a reduced heat transfer. When using RON95E10 gasoline fuel and CR = 10.8, an efficiency gain of up to 1.6% could be achieved with the long-stroke compared to the short-stroke especially at lower engine loads. With methanol and CR = 15, an efficiency gain of up to 1.6% could be achieved with the long-stroke setup compared to the short-stroke engine. Subsequently, lean burn conditions were experimentally investigated with methanol and CR = 15. The longer stroke allowed the lean burn limit to be extended from λ = 1.9 to λ = 2.0 with an efficiency gain of up to 2.2%. A maximum indicated efficiency of 47.4% could be achieved at λ = 1.9 with methanol on the long-stroke engine with CR = 15.
Positive correlation of serum indoxyl sulfate level with peripheral arterial disease in hemodialysis patients
Authors: Chiu Liang-Te , Lin Lin , Lin Huei-Jhen , Lai Yu-Hsien , Hsu Bang-Gee
Published: August 2021

Objectives

Indoxyl sulfate, known for its cardiovascular toxicity, is associated with vascular and coronary artery diseases and increased mortality. Peripheral arterial disease, defined by low ankle–brachial index, is associated with increased mortality in patients on hemodialysis. The present study aimed to determine the relationship between the serum indoxyl sulfate level and peripheral arterial disease in patients on maintenance hemodialysis.

Methods

The present cross-sectional, single-center study included 75 patients on maintenance hemodialysis. Serum indoxyl sulfate levels were determined by high-performance liquid chromatography–mass spectrometry. Ankle–brachial index values were measured using an automated oscillometric device. Patients with ankle–brachial indexes of < 0.9 were categorized into the low ankle–brachial index group.

Results

In the study cohort, 12 of the 75 patients (16.0%) had low ankle–brachial indexes. The rates of diabetes mellitus ( p = 0.010) as well as the serum levels of C-reactive protein ( p < 0.001) and indoxyl sulfate ( p < 0.001) were higher in the low ankle–brachial index group than the normal ankle–brachial index group. The multivariable logistic regression analysis revealed that serum levels of indoxyl sulfate (odds ratio = 1.123, 95% confidence interval 1.011–1.249, p = 0.031) and C-reactive protein (each 0.1 mg/dL increase, odds ratio = 1.169, 95% confidence interval 1.018–1.343, p = 0.027) were independently associated with peripheral arterial disease in patients on maintenance hemodialysis.

Conclusions

Serum indoxyl sulfate levels were associated with peripheral arterial disease in patients on maintenance hemodialysis.
Deconstructing the periphery: Korean degree-seeking students’ everyday transformations in and through India
Authors: Lipura Sarah Jane D.
Published: August 2021

According to dominant perspectives on educational mobilities, India is not an obvious study destination choice and more so not a favoured one for students from South Korea. The aim of this paper is to question this prevalent discourse by drawing attention to the small-sized but rather steady flow of Korean students who have gone to Indian universities for both short-term and long-term educational programmes. Obviously, this unique but underexplored phenomenon is at odds with the prevailing episteme surrounding international student mobilities (ISM) focused on the ‘world-class’ imaginary and East–West, South–North binaries. By presenting empirical data on and from Korean degree-seeking students in India, this study offers fertile understanding of student experiences and imaginings of transformations – those that take place in what have been typecast as ‘peripheral’ study destinations such as India. Drawing on critical scholarship on ISM, this paper seeks to find out what changes and shifts are generated in and through the periphery as a place of study. In particular, it asks: what discourses on transformation do students construct as they experience, imagine and desire changes in their lives through their everyday encounters with and negotiation of India? How are these transformations articulated and how do these articulations, in turn, manifest (de)constructed views of place, of self and of others? And, lastly, how do these narratives shape the broader discourse on educational mobilities and study abroad? In approaching these questions, this paper introduces diverse discourses on ‘everyday transformations’ articulated by students through comparison, contradiction and conjecture.
Social bonding and children’s collaborations as citizen-peers at primary school
Authors: Fitzgerald Caitríona
Published: August 2021

This qualitative research explored 9- to 12-year-old children’s citizenship participation at primary school in the Republic of Ireland. During 2016–2017, 160 children from 6 co-educational primary schools participated. Through a process of grounded analysis, children are identified as active citizen-peers of their peer groups. As citizen-peers, children used social strategies to assert their agency and autonomy within the adult-controlled school environment. Social bonding between children also influenced the ways citizen-peers negotiated peer group social hierarchies. Inductive analysis of observational data identifies children’s social strategies as covert and overt forms of Collective Social Action ( CSA); motivated by competition and/or protest against the activities children did not want to participate in at school. This research found that low social bonding between children affects peer solidarity, which suggests that social bonding is an important aspect of children’s collaboration as citizen-peers at school.
Are poverty and deprivation relevant to general practice in 2021?
Authors: Butler Daniel
Published: August 2021

February 2021 marked 50 years since Dr Julian Tudor Hart’s landmark paper described the ‘Inverse Care Law’. This article explores how applicable the ‘Inverse Care Law’ is today. How do poverty and deprivation have an impact on general practice today? We learn about the health effects of smoking, obesity and age, but it is important to also understand how relevant deprivation and socioeconomic status are to the health of our patients.
Management of erectile dysfunction in primary care
Authors: Varma Rajesh , Sellaturay Senthy
Published: August 2021

Erectile dysfunction (ED) is the persistent inability to attain and maintain an erection sufficient to permit satisfactory sexual performance. ED can affect the physical, emotional, and psychosocial health of the affected man and his partner. ED is an independent risk factor for cardiovascular disease (CVD), stroke and all-cause mortality. This article provides a best practice approach to the management of ED in primary care. The key messages of the article are depicted in two summary flowcharts to support clinical decision-making. Any treatment must satisfy the dual goals of managing the ED symptom and assessing and appropriately managing the heightened CVD risk.
Immune checkpoint inhibitors in ovarian cancer: where do we stand?
Authors: Leary Alexandra , Tan David , Ledermann Jonathan
Published: August 2021

Numerous retrospective studies have demonstrated that the density of intra-tumoral immune cell infiltration is prognostic in epithelial ovarian cancer (OC). These observations together with reports of programmed death ligand-1 (PD-L1) expression in advanced OC provided the rationale for investigating the benefit of programmed death-1 (PD1) or PD-L1 inhibition in OC. Unfortunately clinical trials to date evaluating PD1/PD-L1 inhibition in patients with relapsed OC have been disappointing. In this review we will discuss early results from single agent PD1/PD-L1 inhibitors and the strategies to enhance benefit from immune-oncology agents in OC, including proposing anti-PD-L1 in combination with other agents (cytotoxics, anti-angiogenics, poly(ADP-ribose) polymerase. (PARP) inhibitors, targeted therapies or other immunotherapies), as well as evaluating these agents earlier in the disease course, or in biomarker selected patients.
City logistics challenges and innovative solutions in developed and developing economies: A systematic literature review
Authors: Arvianto Ary , Sopha Bertha Maya , Asih Anna Maria Sri , Imron Muhammad Ali
Published: August 2021

Varying characteristics of developed and developing countries have resulted in different challenges and innovative solutions of city logistics. This study aimed to identify research clusters on city logistics between developed and developing economies and to systematically compare city logistics challenges and associated innovative solutions for both economies. Bibliometric analysis and a systematic literature review were applied to analyze 328 peer-reviewed publications, comprising 229 (70%) and 99 (30%) articles addressing case studies in developed and developing economies, respectively. We discovered six research clusters in city logistics literature for developed countries, compared with only four for developing economies in which public policy has not been addressed. Urban growth, environmental challenges, and traffic congestion are the three major city logistics challenges in both types of economies. Furthermore, fleet increment and inadequate loading/unloading spaces are the city logistics challenges analyzed in the literature on developing countries compared with the literature on developed economies that addresses the challenges of education deficiency, regulation, emergence of new business models, and network accessibility and capacity. Consequently, innovative solutions adopted by developed countries demonstrate varied processes involving technology, policy (including public policy and sustainability measures), infrastructure, and economic measures, while for developing countries, the focus remains on effective and efficient distribution operations using optimization and collaboration efforts.
Identification of the Mechanism of Feiduqing on Viral Pneumonia Based on Network Pharmacology Analysis
Authors: Liu Qian , Xu Yuling , Liu Bowen , Yang Hui , Ma Hanbin , Yang Andi , He Yongzhi , Liu Tao
Published: August 2021

Feiduqing (FDQ) is a traditional Chinese medicine formula used for many years in the treatment of viral pneumonia (VP). However, the effective components of FDQ and the mechanism by which it affects VP remain unclear. The purpose of this study is to determine the multitarget mechanism of the effect of FDQ on VP through determination and in vivo pharmacodynamics combined with network pharmacology. Firstly, the compound–target–pathway network was constructed by using TCMSP, UniProt, GeneCards, STRING, and DAVID databases through Cytoscape 3.7.0. Secondly, the content of the effective components of the original prescription of FDQ was determined. Finally, the pharmacological activity of FDQ in vivo was verified by an animal model, and the active ingredient composition (AIC), selected by network pharmacology was used for antipyretic, antiinflammatory, antitussive, and expectorant symptoms. Seven compounds of FDQ and 22 potential target genes in the treatment of VP with FDQ were identified by network pharmacology analysis. Kyoto Encyclopedia of genes and genomes enrichment analysis results indicated that the mechanism of FDQ in the treatment of VP was mainly related to pathways in cancer, hepatitis b, tumor necrosis factor (TNF) signaling pathway, Chagas disease, tuberculosis, influenza A, human T-cell leukemia virus, type 1 infection, toxoplasmosis and toll-like receptor signaling pathways, osteoclast differentiation, nonalcoholic fatty liver disease, and leishmaniasis. The results of pharmacodynamic experiments showed that FDQ and AIC possessed antipyretic, cough relieving, and reducing sputum effects. Besides, FDQ and AIC could also significantly reduce the content of prostaglandin E2, TNF-α, cyclic adenosine monophosphate, interleukin-1β, and myeloperoxidase in vivo, while increasing the content of interleukin-10 in vivo. The active ingredients of FDQ prescriptions could be accurately screened by network pharmacological analysis, as they clarified the mechanism of FDQ in the treatment of VP. The research results provided potential ideas and methods for the screening and purification of active ingredients in traditional Chinese medicine prescriptions.
Marital Conflict and Destructive Resolution Tactics: The Case of Bahir Dar City, Ethiopia
Authors: Tolla Tiruwork Tamiru
Published: August 2021

This study was conducted to examine the major causes of marital conflicts among couples in their day-to-day marital disagreements, the proportion of destructive conflict resolution tactics, the level of destructive conflict tactics, and the differences of destructive conflict tactics within couples. A total of 188 married women who live in Bahir Dar city were participated in the study. Causes of Marital Conflict Questionnaire and Conflict Tactics Scale were used to collect quantitative data. In addition, interview was conducted with eight participants to substantiate the quantitative findings. The result revealed that household responsibility, follow-up of child education, child caring, disparity in parenting, misunderstanding, lack of interest to generate income, carelessness, insufficient income for the family, extravagance, and lack of intimacy are found to be the major causes for marital conflict. It was also found that 60 percent of these participants employed destructive reasoning and 5 percent of them employed each verbal aggression and physical aggression frequently while resolving their marital dispute. The repeated-measures t-test results also showed that these participants practiced more destructive reasoning than verbal aggression and physical aggression, and more verbal aggression than physical aggression. Therefore, it was concluded that by practicing frequent destructive reasoning tactics, majority of the families of these participants seem placing themselves at risk of applying more hostile conflict tactic and obstructing their happiness.
The right to request flexible working arrangements under the Work-life Balance Directive – A comparative perspective
Authors: Waddington Lisa , Bell Mark
Published: August 2021

The 2019 Work-life Balance Directive creates a new right for parents and carers to request flexible working arrangements for caring purposes. The significance of this innovation has been heightened by the pandemic because it includes the right to request remote working arrangements. This article undertakes a contextual and comparative analysis in order to understand better the strengths, limitations and opportunities created by the Directive. It compares the right to request flexible working arrangements to provisions found in existing Directives on parental leave and part-time work, as well as protections that may be derived from EU equality law. It looks also at examples of existing legislation in two jurisdictions, the Netherlands and Australia, in order to illustrate the options available to Member States when they implement this right within domestic law. The article concludes that the full potential of this right can only be understood when it is viewed as part of a wider range of legal provisions that assist in the reconciliation of work and family life.
The impact of coronavirus disease 2019 pandemic on working dynamics of junior and middle grade doctors in the United Kingdom: Learning from their experience requires immediate improvement in health care planning and management—An outcome analysis of a nationwide survey
Authors: Abbas Madiha , Ghazanfar Abbas
Published: August 2021

Objectives:

Severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019) pandemic had an unprecedented impact on health services across the world resulting in increased demand of intensive care capacity, opening Nightingale hospitals, and mass movement of doctors across various specialities. This unplanned redeployment raised concerns among various health care workers. The objective of the current study is to explore working dynamics and experience of junior and middle grade doctors during current pandemic.

Methods:

We organised a nationwide cross-sectional survey of junior and middle grade doctors working in the United Kingdom. The survey was aimed to study their level of participation during coronavirus disease 2019 pandemic and its impact on their clinical practices and well-being.

Results:

In total, 1564 completed questionnaires with representations from all regions of the United Kingdom were included. The mean age of respondents was 30.64 years (95% confidence interval +1.025; standard deviation = 9.9057). There were 51.5% females with significantly more participants from Black, Asian, and minority ethnic group ( n = 835, p = 0.0073); 963 (61.6%, p ⩽ 0.0001) doctors were redeployed outside their primary speciality. The major redeployments were from other specialities to Intensive Therapy Units (41.8%, p ⩽ 0.001); 63.3% of respondents spend more than 8 weeks in redeployed speciality ( p ⩽ 0.0001). There was a significant impact of coronavirus disease 2019 on personal, mental, and physical well-being of doctors. The major areas requiring immediate attention include proper leadership and clinical support (64.1%), pre-redeployment planning and induction (48.5%), redeployment according to the skills and/or in familiar specialities (44.6%), and regular mental and physical well-being checks (37%).

Conclusion:

The outcome of the survey concluded with four major recommendations, including the need to have a named supervisor for these doctors, structured induction program, regular well-being checks, and involving them in crisis planning. These recommendations will help to shape future health care policies and management particularly when it is related to redeployment of doctors during any crisis or pandemic.
Prevalence, characteristics and predicting risk factors of adverse drug reactions among hospitalized older adults: A systematic review and meta-analysis
Authors: Yadesa Tadele Mekuriya , Kitutu Freddy Eric , Deyno Serawit , Ogwang Patrick Engeu , Tamukong Robert , Alele Paul E
Published: August 2021

Background:

Occurrence of adverse drug reactions is a major global health problem mostly affecting older adults. Identifying the magnitude and predictors of adverse drug reactions is crucial to developing strategies to mitigate the burden of adverse drug reactions. This study’s objectives were to estimate and compare the prevalences of adverse drug reactions, to characterize them and to identify the predictors among hospitalized older adults.

Methods:

A comprehensive systematic literature search including both prevalence and risk factors of adverse drug reactions in hospitalized older adults was conducted using PubMed, Scopus and Google Scholar, involving all articles published in English. Descriptive statistics and comparison of means was performed using SPSS version 20.0 and metaprop command was performed in STATA version 13.0. Heterogeneity was assessed using I2 statistic.

Results:

A total of 18 studies, involving 80,695 participants with a median age of 77 years, were included in this study. The pooled prevalence of adverse drug reaction was 22% (95% confidence interval: 17%, 28%; I2 = 99.23%). Among high-income countries, the prevalence of adverse drug reactions was 29% (95% confidence interval: 16%, 42%) as compared to 19% (95% confidence interval: 14%–25%) in low and middle-income countries ( p value = 0.176). Of the 620 adverse drug reactions categorized, most were type A (89%), which are generally predictable and preventable. Two-thirds (795, 67%) of the adverse drug reactions were probable and most (1194, 69%) were mild or moderate. The majority (60%) of the categorized adverse drug reactions were preventable and less than one-third (31%) were severe. The most consistently reported predictors of adverse drug reactions in hospitalized older patients were medication-related factors, including polypharmacy and potentially inappropriate medications followed by disease-related factors—renal failure, complex comorbidity, heart failure and liver failure.

Conclusion:

Almost one-quarter of all hospitalized older adults experienced at least one adverse drug reaction during their hospital stay. The majority of the adverse drug reactions were preventable. Medication-related factors were the most consistently reported predictors of adverse drug reactions followed by disease-related factors.
Attitude and self-care practice on hypertension among antihypertensive medication users in a tertiary care hospital Nepal
Authors: Shrestha Jyoti , Marasine Nirmal Raj , Lamichhane Rajendra , Marasini Nabin Raj , Sankhi Sabina
Published: August 2021

Background:

Hypertension a “silent killer” is a serious global health problem, whose prevalence is increasing in Nepal.

Objective:

This study aimed to determine the attitude and practice of hypertension among anti-hypertensive medication users in a tertiary care teaching hospital in western Nepal.

Methodology:

A hospital-based cross-sectional study design was used among 136 hypertensive patients under medication, aged ⩾ 30 years, and visiting medical outpatient department, medical ward, and geriatric ward, using a non-probability convenience sampling technique. Semi-structured questionnaires were used for data collection through interviews. Descriptive and inferential statistics were used, and a p value < 0.05 was considered statistically significant.

Results:

Most of the patients were male (56.6%), mean ± standard deviation age was 56.74 ± 12.58. Majority of them were Hindu (69.9%), upper caste people (29.4%), illiterate (22.1%), and house maker (27.2%). Half of the patients (50.7%) had a positive attitude and more than half (52.2%) had performed adequate self-care practice. Selected variables such as educational status and dietary pattern and attitude were significantly associated, whereas no association was found between sociodemographic variables and self-care practice. Attitude and self-care practices were found strongly associated with one another (p = 0.002).

Conclusion:

Our study found that half of the study population had positive attitude, and more than half of them had performed adequate self-care practice. Hence, educational interventions and awareness programs on dietary aspects should be focused for improving the attitude and practice of all the patient groups.
Risk factors associated with cat parasites in a feline medical center
Authors: Iturbe Cossío Tamara Libertad , Montes Luna Azucena Danae , Ruiz Mejia Magdalena , Flores Ortega Ariadna , Heredia Cárdenas Rafel , Romero Núñez Camilo
Published: August 2021

Objectives

The present study was carried out to evaluate the risk factors for and presence of intestinal parasites in cats at the feline hospital ‘CEME Gatos’, Mexico City.

Methods

In total, 528 fecal samples from domestic cats were collected and analyzed in order to diagnose enteroparasites.

Results

The parasite with the highest prevalence was Giardia species (21.97%), followed by Cryptosporidium species (7%), Toxocara cati (6.45%), Cystoisospora species (5.11%) and Dipylidium caninum (0.76%). One hundred and twenty-one cats (55.50%) were infected with a single parasite, 80 (36.69%) were infected with two and 17 (14.04%) were infected with three parasites. The results of the prevalence study showed that a liquid consistency of feces was associated with the presence of Giardia species, whereas age <7 months and mucus in the stool were factors associated with the prevalence of Cystoisospora species. Regarding T cati, the associated risk factors were age <7 months, being male, contact with other animal species and access to the outdoors. The last factor was strongly associated with the presence of T cati (eight times more likely) in outdoor cats’ feces. Brushing frequency was also an associated factor: T cati was present in cats that were never brushed. The results of the analysis of cats infected with D caninum showed that interaction with other species was a risk factor for infection.

Conclusions and relevance

Age <7 months, mucus in feces, living with other animal species, outdoor access and frequency of brushing are risk factors for the presence of parasites.
A choir or cacophony? Sample sizes and quality of conveying participants’ voices in phenomenological research
Authors: Bartholomew Theodore T , Joy Eileen E , Kang Ellice , Brown Jill
Published: August 2021

Misunderstandings about qualitative methods, whether phenomenological or otherwise, are prevalent in social science research. Such misunderstandings leave researchers, reviewers, and editors less equipped to conduct or evaluate this method. Evaluation of phenomenology is especially complicated given the different variants that exist and the need for flexibility within these studies. Methodologists have created guides for conducting specific variants of phenomenology; however, these do not provide clear guidance as to what is an adequate sample in phenomenology. The purpose of this systematic review was to help improve implementation of phenomenological methods by exploring sample issues as they relate to study quality. We implemented an explanatory sequential mixed methods design to test relationships between samples and studies’ quality then deepen our understanding of these findings with a focused content analysis. First, we reviewed and coded 200 manuscripts following the PRISMA method. Larger samples were associated with lower quality and studies aligned with a specific phenomenological method tended to be of higher quality. Second, we identified two cases from the studies reviewed and subjected them to deductive qualitative content analysis to identify features that demonstrate quality. Findings are discussed with respect to implications for phenomenological methods in social and health sciences.
Perilunate Dislocation Above the Age of 65 Years: Case Series and Review of Literature
Authors: Rubin Guy , Eliyahu Amir , Grinbaum Erez , Rozen Nimrod
Published: August 2021

Introduction

Perilunate and fracture dislocations predominantly follow a high-energy mechanism. Perilunate dislocations have an incidence of 0.5/105 individuals/year, occurring at a mean age of 26 years and are frequently seen in men. This study aimed to describe the characteristics of this injury in elderly population of patients using literature review and our experience with four cases aged >65 years.

Materials and Methods

We treated four patients with perilunate dislocation aged >65 years. All the patients’ medical records were reviewed retrospectively. A literature review for case studies of perilunate dislocation was conducted with the purpose of finding cases including patients aged >65 years.

Results

Three of our patients had injuries that were missed in the first visit in the emergency department. The mechanism of injury was high energy in only two patients. Two patients had posterior perilunate dislocation, while the other two had transradial perilunate dislocation. Three patients were available for follow-up. The overall outcome was satisfaction according the Mayo wrist score and minimal disability according to the Disabilities of the Arm, Shoulder and Hand score. All patients reported that pain was absent and they were able to return to their regular activities. The literature review found only seven papers documenting treatment of patients aged >65 years.

Discussion

Perilunate dislocation is extremely rare in the population aged >65 years. Although the rate of missed diagnosis in our cohort was extremely high, the overall satisfaction and return to function was high.

Conclusions

This case series and literature review highlight the unique characteristics of this injury in the age group of patients aged >65 years. Although perilunate dislocation in patients aged >65 years is rare, clinicians should be aware of the presentation of this condition in the elderly.
The Disjuncture between Medication Adherence and Recovery-centered Principles in Early Psychosis Intervention: An Institutional Ethnography
Authors: Stasiulis Elaine , Gibson Barbara E. , Webster Fiona , Boydell Katherine M.
Published: August 2021

To examine how recovery principles are enacted in an early psychosis intervention (EPI) clinic, we used an institutional ethnographic approach focused on how the ideology of medication adherence organizes young people’s experiences of EPI services. Methods included ethnographic observation, in-depth interviews with 27 participants (18 clinic staff, four young people, and five family members), and textual analysis of clinic documents (e.g., case files, administrative forms, policy reports). The disjuncture between service providers’ intent to provide recovery-principled care and the actual experiences of young people is actualized in institutionalized practices of informal coercion around medication adherence, which we identify as “enticing,”“negotiating,” and “taking responsibility.” We link these practices to institutional accountability, risk, and efficiencies, and discuss the need for a shift in medication management approaches in EPI settings.
Enhancing Trust Between PPP Partners: The Role of Contractual Functions and Information Transparency
Authors: Cheng Mengyuan , Liu Guoliang , Xu Yongshun , Chi Ming
Published: August 2021

Contracts are essential for managing the relationship among public–private partnership (PPP) partners. However, the impact of contracts on the trust between partners is unclear, especially in PPP projects. From the multifunctional perspective of contracts, this study aims to investigate how different dimensions of contractual functions affect distinct types of trust and the moderating role of information transparency between them. The empirical results of the data collected from Chinese PPP professionals show that the three dimensions of contractual functions have positive effects on trust, including goodwill trust and competence trust. However, contractual adaptation has the strongest impact. Moreover, information transparency positively moderates the relationship between contractual control, adaptation, and trust. This study provides new insights on contracts and trust in PPP projects. It can guide PPP project partners to value the process of contract design and information disclosure to cultivate specific types of trust.
Qualitative Research Methods in Translation Theory
Authors: Glynn Dominic
Published: August 2021

This article analyses different methodological approaches adopted by theoretical articles published in translation studies journals. To account for the range of perspectives, a small corpus comprising articles from three journals listed in both the Thomson and Reuters Social Sciences Citation Index (SSCI) and the Arts and Humanities Citation Index (A&HCI) was studied. The article discusses how the methods used could gain in rigor from being formalized. It begins by defining translation theory before outlining a corpus of articles to be studied. It then moves onto describing and discussing four methodologies to provide recommendations for conducting future research in translation theory.
“Normalizing” Everyday Life in the State of Emergency: Experiences, Well-Being and Coping Strategies of Emerging Adults in Serbia during the First Wave of the COVID-19 Pandemic
Authors: Vuletić Teodora , Ignjatović Natalija , Stanković Biljana , Ivanov Ana
Published: August 2021

Although emerging adults are generally more physically resilient to the severe effects of COVID-19, they might be vulnerable to the psychological stressors brought about by the crisis. Using semi-structured interviews, this qualitative research aimed to explore the experiences, well-being, coping strategies and future expectations of 15 emerging adults in Serbia during the state of emergency caused by the global pandemic. As a result of thematic analysis, six main themes emerged, focusing on: 1) disruptions in everyday life and functioning; 2) the pandemic as a health crisis; 3) public reaction to the pandemic as a source of tension and frustration; 4) crisis as an opportunity; 5) coping strategies; 6) imagining the post-pandemic future. The present study points to the resilience and resourcefulness of emerging adults in the local context and emphasizes the heterogeneity of this age group and the vulnerability sources of those who might need additional support.
Single Digit Index Finger Amputation—To Replant or Not?
Authors: Thibedeau Marshall , Ramji Maleka , McKenzie Madeleine , Yeung Justin , Nickerson Duncan A.
Published: August 2021

Background: Single index finger replantation is often listed as a contraindication due to its hindrance of hand function when replanted. Recent studies demonstrate comparable subjective and global functional outcomes for index flexor zone II finger replants versus revision amputations. We therefore sought to identify current opinions of plastic surgery trainees and staff treating single index finger zone II amputations including influential patient and injury characteristics. Methods: With the approval of the Canadian Society of Plastic Surgery, a 17-question survey was sent via email to all listed members on 3 separate occasions. Participation was voluntary and survey responses were compiled and analyzed using SPSS statistical software. Results: Survey response rate was 38.5%. When asked whether the surgeon would replant a single index digit, flexor zone II, sharp amputation, 55.3% of respondents chose “yes,” while 44.7% responded “no.” Staff (51.5%) were less likely to replant a single index digit amputation. Likelihood of replant dropped substantially in crush (12.4%) and avulsion (17.1%) injury. Smoking was the most likely patient characteristic to change a surgeon’s decision (61.9%). Poor range of motion (77.5%) and patient satisfaction (72.5%) were the most frequently listed reasons not to replant. Conclusion: Among Canadian plastic surgeons, there exists disagreement in how single index flexor zone II amputations should be managed. In review of the literature, these notions and previous teaching around replants highlight many inherent surgeon biases with regard to the merit and value of single digit replantation.
Epithelioid sarcoma: A single-institutional retrospective cohort study of 36 cases
Authors: Zhang Shuguang , Jing Changyou , Liu Huanmei , Zhao Zhenguo , Zhang Xinxin , Liu Ting , Xu Songfeng , Xu Libin , Yu Shengji
Published: August 2021

Background:

Few studies have focused on the correlation between the clinical variables and the survival in Epithelioid Sarcoma (ES). The aim of this study was to investigate the relevant clinical variables influencing the survival of ES patients.

Methods:

From March 2000 to April 2018, 36 patients (median age, 38 years, range 22–61 years) with ES were evaluated, treated, and followed up.

Results:

All 36 patients underwent resection in our hospital. Among them, the 2 and 5 years local recurrence rates were 32.0% and 45.1%, respectively, with a better prognosis in patients with R0 resection margin. Distant metastasis rates for the 33 patients with M0 after 2 and 5 years were 51.5% and 70.8%, respectively. Overall survival rates at 2 and 5 years for 36 patients were 74.8% and 43.3%, respectively. Tumor size (>5 cm) and M1 were significantly associated with a poor overall survival. But the R0 resection margin was the only prognostic factor for influencing the LRFS and DMFS.

Conclusions:

The R0 resection margin and small tumor size were critical for a better prognosis.