bluuebunny/crossref_metadata_2025 huggingface dataset:
Recherche et caractérisation des cryoglobulinémies chez les donneurs de sang porteurs des anticorps anti-VHC à Lubumbashi, République Démocratique du Congo
Authors: Baleebenga Adolphe , Kabamba-Tshikongo Arsene , Longanga-Otshudi Albert
Published: February 2024

La cryoglobulinémie constitue une des formes extra-hépatiques d’aggravation de l’hépatite C. A notre connaissance, aucune étude n’a  été réalisée à ce jour à Lubumbashi sur ce sujet. Cette étude avait pour objectif de déterminer la prévalence et les types de cryoglobulines  chez les donneurs de sang porteurs de l’hépatite C dans la ville de Lubumbashi. Il s’est agi d’une étude descriptive  transversale analytique réalisée de novembre 2021 à juin 2022 à la banque de sang de l’hôpital Jason Sendwe à Lubumbashi. Au total,  1901 échantillons collectés chez les donneurs de sang avaient été analysés. La détection des cryoglobulines était réalisée par la méthode  de précipitation à froid et leur caractérisation par électrophorèse capillaire. Pour le dépistage des anticorps anti-VHC, nous avons utilisé  les tests de diagnostic rapide (TDR) et la mesure des paramètres biochimiques avait été réalisée par la méthode spectrophotométrique.  La prévalence des anticorps anti-VHC et des cryoglobulines était de 4,9% et 46,8% respectivement. Les cryoglobulines identifiées étaient  de type I, II et III. Les perturbations des paramètres biochimiques étaient plus élevées chez les donneurs de sang porteurs d’hépatite C  avec cryoglobulines. La détection et caractérisation des cryoglobulines fournissent une orientation vers l’identification d’une éventuelle  maladie sous-jacente.

 

English title: Research and characterization of cryoglobulinemia in blood donors with antiHCV antibodies in  Lubumbashi, Democratic Republic of Congo 

Cryoglobulinemia constitutes one of the extra-hepatic forms of severe hepatitis C. To the  best of our knowledge, no study has been carried out to date in Lubumbashi on this subject. This study aimed to determine the  prevalence and types of cryoglobulins among positive hepatitis C blood donors in Lubumbashi. This was a descriptive, analytical, cross- sectional study carried out from November 2021 to June 2022 at the blood bank of Jason Sendwe Hospital of Lubumbashi. In total, 1901  samples collected from blood donors were analyzed. The detection of cryoglobulins was carried out by the cold precipitation method  whereas their characterization was performed by capillary electrophoresis. For the screening of anti-HCV antibodies, we used rapid  diagnostic tests (RDT) and biochemical parameters were assessed using the spectrophotometric method. The prevalence of anti-HCV  antibodies and cryoglobulins was 4.9% and 46.8% respectively. Types I, II and III cryoglobulins were identified. Disturbances in  biochemical parameters were higher in hepatitis C blood donors with cryoglobulins. The detection and characterization of cryoglobulins  provide guidance towards the identification of a possible underlying disease.
Assessing the prevalence of aflatoxin B1 in poultry feed in Dakar, Senegal: implications for animal and public health
Authors: Minougou Nadege , Kabore Aristide Benewende , Savadogo Madi , Dera Mikhailou Kiswend-Sida , Dahourou Dieudonne Laibane
Published: February 2024

Aflatoxin B1 (AFB1) is a mycotoxin that can contaminate a wide variety of foodstuffs such as animal feed. Most of the ingredients used in  livestock feed are highly susceptible to contamination, with a propensity to release residues in products intended for human  consumption. In the case of the poultry industry, the ingestion of contaminated feed by poultry can lead to alterations in their sanitary  and zootechnical performance. It also may cause a food safety problem related to the presence of mycotoxin residues in animal products.  The objective of this study was to determine the prevalence and level of AFB1 in poultry feeds/ingredients used or marketed in  the city of Dakar and its suburbs, and to discuss the potential risks to animal and human health. In total, 68 samples of starter, grower,  finisher, pullet, and layer feeds and 2 ingredients samples were analysed. The research and quantification of AFB1 were done using the  high-performance liquid chromatography (HPLC) method, as described in ISO 14718. The results showed that all (100%) of the samples  were contaminated with levels ranging from less than 0.1 ppb to 52.3 ppb in the feeds. The level in ingredients samples were 0.5 and  177.5 ppb respectively for the fish flour and peanut meal. Of all the samples analysed (feeds and ingredients), 5.7% had contamination  levels above the allowable limits for poultry feed. Given these results and the threat to public health posed by the increasing consumption  of poultry products, it would be judicious to systematically include the research of mycotoxins in raw materials, along with  the bromatological analyses used for food formation. Additionally, a study on mycotoxin residues in foodstuff from poultry would be of  great interest for the protection of public health and food safety.
Enhancing Power Quality with PDO-FOPID Controller in Unified Power Quality Conditioner for Grid-Connected Hybrid Renewables
Authors: Nagaraju S. , Chandramouli B.
Published: February 2024

Addressing the pressing research problem of power fluctuations and grid harmonics in the integration of renewable energy, our  proposed control strategy utilizes the Prairie Dog Optimization Fractional Order Proportional Integral Derivative (PDO-FOPID) controller  within a Unified Power Quality Conditioner (UPQC) system. This innovative approach is tailored to mitigate harmonics and meet load  requirements in grid-connected hybrid renewables. The UPQC system is instrumental in regulating coupling point voltage, countering  voltage and current harmonics to enhance overall power quality. The PDO-FOPID controller dynamically adapts control parameters to system dynamics and load changes, ensuring a stable power supply despite the variability of renewable sources. Simulations in MATLAB/ Simulink confirm its superiority over traditional control strategies, such as PI, sliding mode, and fuzzy control, in harmonics mitigation,  load fulfilment, and power stability. By effectively addressing these challenges, our proposed solution not only contributes to resolving a  critical research problem but also advances the seamless integration of Hybrid Renewable Energy Sources (HRES) into power systems,  thereby enhancing overall grid performance and the efficacy of renewable energy integration.
High Impedance Fault Detection and Localization Using Fully-Connected Convolutional Neural Network: A Deep Learning Approach
Authors: Abasi-obot I.E. , Kunya A.B. , Shehu G.S. , Jibril Y.
Published: February 2024

The detection and localization of high impedance faults (HIF) in power systems are challenging due to the low fault current magnitude,  which often falls below the detection threshold of conventional devices. HIF events introduce harmonics into the network, posing risks to  the safety of connected equipment, including the potential for igniting fire which endangers lives and properties. In this study, Emanuel's  HIF model was used to generate HIF signatures resembling real HIF events. Model parameters were adjusted to mimic  various contact surface impedances. Two datasets were created: 'no-fault' data, simulating the network without HIF, and 'fault' data,  incorporating HIF waveforms by simulating single and multiple lines with the HIF model. The faulted line was divided into five segments along the 33 kV line to capture fault signatures at different locations. The generated data, including current waveforms and magnitudes,  were processed and divided into an 80:20 ratio for training, validation, and testing using a deep fully connected Convolutional Neural  Network for HIF detection and location. The results showed an impressive accuracy rate of 99.44% and 99.78% for detection and location  respectively, representing a significant advancement in HIF detection and location, and offering practical applications for enhancing  power line safety.
SEPs infringement and competition law defence in German case law
Authors: Colangelo Giuseppe , Aguggia Andrea
Published: February 2024

Within the debate on the role of competition law in standard essential patents (SEPs) litigation, German case law has taken centre stage because of the number of decisions handed down and its traditional patent-owner-friendly approach. As the framework handed down by the European Court of Justice (CJEU) in Huawei is usually interpreted as being opposed to the approach adopted by the German Federal Court in the Orange Book Standard decision, it is worth investigating how German courts have tackled the competition law defence in the post-Huawei scenario. The article maintains that the Federal Court’s rulings in Einwand have aligned German case law with the Huawei framework and that the attention devoted in German case law to the implementer’s obligations is consistent with the principles set out by the CJEU. Nonetheless, recent lower courts’ decisions confirm that the case-by-case detection of the licensee’s willingness is still a challenging issue.
Scoping Literature Review Study of Short Message Services (SMS) and Mobile App-Based Technology as an mHealth tool for Active Participant Centered (MAPC) Adverse Events Following Immunisations (AEFIs) Surveillance using a Low Middle-Income Country (LMIC) lens
Authors:   Pharmacovigilance and Clinical Trials Division, Medicines Control Authority of Zimbabwe, Harare, Zimbabwe, Nyambayo Priscilla PM , Gold Michael S , Mehta Ushma C
Published: February 2024

INTRODUCTION Mobile technology is rapidly expanding globally. Uptake of such technologies to improve Adverse Events Following Immunisation (AEFIs) surveillance in most Low Middle-Income Countries (LMICs) settings is limited. There is limited evidence on the feasibility of such mHealth Active Participant Centered (MAPC) AEFI surveillance systems in LMICs. This scoping literature review study therefore focused at assessing the value and feasibility of mHealth active participant centered (MAPC) AEFI surveillance using SMS and /or mobile applications (apps) immunisation safety from the perspective of a LMIC. AIM The aim of the scoping literature review was to generate exploratory feasibility evidence of MAPC AEFI surveillance such as SMS response rates, AEFI reporting rates, cost implications, acceptability, and challenges from LMICs perspectives. METHODS Employing the Joanna Briggs Institute (JBI) approach for scoping reviews, we conducted literature review of MEDLINE via PubMed, Scopus, CINAHL and Africa -wide via EBSCOs, and the Cochrane Library for studies conducted from 1970 up to July 2022. Studies were assessed on type of mHealth platform, country of implementation, key findings of uptake, acceptability, response rates, cost and key challenges identified. Most studies 24/26(92%) were conducted in HICs from 2010 to July 2022, with evidence of MAPC AEFI surveillance improving consumer response rates and early AEFI reporting for most vaccines. The consumer vaccines SMS mean response rate was 71% for 23 studies using mixed digital technologies methods mostly conducted in HICs. These HICs have more well-resourced consumers, adequate immunisation AEFI surveillance programs and well-funded primary healthcare services. LMICs suffer from critical resource limitations to the extent that over 50 LMICs rely on donor funding for vaccine procurement. There was limited MAPC AEFI surveillance in LMICs of two published feasibility studies with no evidence of scale up. CONCLUSION MAPC AEFI surveillance is implemented mostly in HICs hence need for MAPC AEFI surveillance feasibility studies in LMICs taking advantage of increasing availability of mobile phone technology.
CBR Mapping Prediction from 2D Resistivity Imaging Using Regression Following Archie’s Formula
Authors: El Basri Mohamed , Harmouzi Hasnaa , El Basri Lahcen , Mastere Mohamed , Ouchen Ibrahim , El Fellah Bouchta , Benzougagh Brahim
Published: February 2024

Indirect geophysical methods are increasingly associated with direct underground methods in investigating the subsurface to address environmental and geotechnical problems and reduce the cost of underground studies. These methods make it possible to explore large areas with acceptable precision, time, and cost. The present study combines the electrical resistivity method with the California Bearing Ratio for exploring an area located west of the Nouakchott port in Mauritania. The study aims firstly to verify that the thickness of the backfill layer must be less than 2 m throughout the entire study area and secondly to map areas with low California Bearing Ratio values (<80%) indicating substandard backfill compaction using 2D Electrical Resistivity Tomography imaging survey and regression. The measured Electrical Resistivity values exhibit a good nonlinear regression with California Bearing Ratio, following Archie's equation. A map of California Bearing Ratio variation was derived from the Electrical Resistivity values, indicating the distribution and variation of soil strength in the study area. The results revealed that the backfill layer did not meet the standards, with approximately 35% of the total area having a California Bearing Ratio value below 80%. The areas with poor compaction requiring treatment were primarily located in the southern sector, followed by the middle and eastern sectors.
Thematic Analysis through Artificial Intelligence (AI)
Authors: Christou Prokopis
Published: February 2024

Thematic analysis, a well-enforced qualitative analytic method, is likely to continue evolving with the adoption of AI technologies. This how-to report does not delve into the details of thematic analysis itself, as there are ample existing studies on the topic. Instead, it acknowledges the potential impacts, dynamics, and pitfalls of AI in thematic analysis while offering valuable advice, particularly for novice analysts, on how to incorporate and document AI tools in each phase of a thematic analysis. The author underscores the importance of not allowing AI to overshadow the analyst's critical evaluative and interpretive skills but instead supporting the use of AI as an aid in thematic analysis, enhancing the depth and breadth of analysis, provided certain criteria are adhered to. This approach ensures that AI serves as a complementary tool, augmenting rather than replacing human analytical inquiry.
PERANAN FAKTOR-FAKTOR YANG DAPAT MEMPENGARUHI PRODUKTIVITAS KERJA KARYAWAN PADA PT. DAMAR RESOURCES
Authors: Aunul Kholik Jajang Roni , Suryati Adelina
Published: February 2024

Employee work productivity is a very important factor to be developed in the company environment, because it has a big role in determining the success or failure of a company in achieving its goals. Comprehensive knowledge and understanding of the determinants that can affect work productivity must be studied in more detail. This research was conducted to determine the role of the factors that can affect employee productivity at PT. Damar Resources. This research method was carried out using a qualitative descriptive approach using a sample  of ten company employees. The results of the study show that the variables of education, competence, discipline, motivation, age, compensation/wages, and work environment as a whole have an good role in influencing employee work productivity. The discipline variable is the main and most dominant factor that influences work productivity because it has been exemplified directly by the leadership which determines the level of employee discipline, a high sense of responsibility from employees for each job, as well as employee discipline by coming and going home on time according to working hours. create a more productive work environment. Providing bonuses/incentives for achieving company targets, increasing work competencies through education, training, or competency certification, as well as providing conducive working facilities and spaces and an atmosphere that is safe, calm, and away from noise should be carried out by companies in order to increase employee work productivity.
PENGARUH BEBAN OPERASIONAL/PENDAPATAN OPERASIONAL (BOPO) TERHADAP KINERJA KEUANGAN PADA PT BANK RAKYAT INDONESIA TBK (PERIODE 2017-2022)
Authors: Mirah Mirah , Ayunani Faras Zulina
Published: February 2024

This study aims to determine the partial and simultaneous effect of Operational Expenses/Operating Income (BOPO) on Financial Performance at PT Bank Rakyat Indonesia Tbk (2017-2022 Period). This study uses secondary data. The population in this study is the Financial Statements of Bank Rakyat Indonesia which are registered with BRI. The technique used to analyze the data used is the classical assumption test and simple linear regression test. The results of this study indicate that partially BOPO has a significant effect on ROA. The results of the t test were obtained at -6.985. The t-test significance value was obtained at 0.002. A significance value of less than 0.05 indicates that BOPO has a significant effect on ROA. Meanwhile simultaneously BOPO has an effect on ROA. The results of the F test were 48.787. The F value of the significance of the test was obtained at 0.002. A significance value greater than 0.05 indicates that BOPO has a significant effect on ROA.
PERANCANGAN ARSITEKTUR ENTERPRISE SISTEM INFORMASI BAPENDA MENGGUNAKA TOGAF
Authors: Yunita Selviana , Fitriani Noorhikmah , Widianto Febri
Published: February 2024

The Regional Revenue Agency (BAPENDA) is an element that carries out supporting functions in the financial sector as well as co-administration tasks and the Regional Revenue Agency has the task of implementing regional policies in the field of regional tax revenue management where regional taxes are divided into two types: taxes managed by the state government and taxes managed by districts and cities. A tax manager, on the other hand, is run by a regional revenue agency or agency. The Regional Revenue Agency is an agency under and responsible to the Governor through the Regional Secretary of the Bappenda led by the Head of the Agency which is under and responsible to the Regent through the Regional Secretary. The Secretariat is led by a secretary who has the main task of assisting the Head of the Agency in carrying out the organization, administration, regional property, household, public relations, protocol, staffing, planning, performance and financial reporting. In planning the enterprise architecture at BAPENDA, Sampit City, the TOGAF ADM (Architecture Development Method) method is used as a system development guideline that will assist organizational activities. The enterprise architecture design includes the planning, design, implementation and maintenance of systems that will be used within the organization. This will ensure that the system used is in accordance with the needs of the organization and can assist in increasing efficiency and effectiveness in the organization's business activities.
RANCANG BANGUN APLIKASI RESERVASI HOTEL DEWIZA RESTO & CONVENTION HALL MENGGUNAKAN FRAMEWORK CODEIGNITER
Authors: Hendra Yul , Tarigan Rehulina , Badru Badru
Published: February 2024

Currently there are still many hotels that do not have a hotel reservation information system. One of them is the Dewiza Hotel & Convention Hall which is a residence located in Banjarsari, Kec. Cipocok Jaya, City of Serang. Dewiza Hotel reservations cannot be made online, they still use a stand-alone based application, meaning that prospective customers must come directly to the hotel to find out room availability, room rates and other facilities owned by the hotel. So that the lack of convenience in the process of booking room services by prospective customers because they cannot see the updated list of rooms, facilities, and their prices. For this reason, a solution is needed so that hotel reservation services can be done online, so that customers can enjoy room booking services and facilities through their gadgets without having to come to the hotel. The methodology used for system development is the ADDIE method using the PHP programming language. This study aims to produce a website that can be accessed online by hotel customers. This website can make it easier for prospective customers to be able to see a list of rooms and room facilities through a website. Prospective customers can make room reservations and see the status of hotel availability, which is always updated by hotel operators.
STUDI PERBANDINGAN EFEKTIVITAS IKLAN FACEBOOK VERSUS IKLAN TRADISIONAL DALAM MENINGKATKAN BRAND AWARENESS
Authors: Ario Tri Wibowo Kresno , Setiyawan Eko
Published: February 2024

Penelitian ini bertujuan untuk membandingkan efektivitas iklan Facebook dengan iklan tradisional dalam meningkatkan brand awareness. Brand awareness menjadi faktor penting dalam membangun citra merek yang kuat dan mempengaruhi keputusan pembelian konsumen. Dalam era digital, Facebook telah menjadi platform pemasaran yang populer dengan jangkauan yang luas dan kemampuan targeting yang canggih. Namun, iklan tradisional seperti iklan cetak dan iklan televisi masih digunakan secara luas. Penelitian ini menggunakan metode penelitian eksperimental dengan kelompok kontrol acak. Dalam eksperimen ini, dua kelompok peserta akan diekspos pada iklan Facebook dan iklan tradisional secara acak. Pengukuran dilakukan sebelum dan setelah eksposur iklan untuk mengevaluasi perubahan dalam tingkat brand awareness. Data juga akan dikumpulkan melalui survei untuk memperoleh persepsi peserta terhadap kedua jenis iklan. Hasil dari penelitian ini diharapkan dapat memberikan pemahaman yang lebih baik tentang efektivitas iklan Facebook versus iklan tradisional dalam meningkatkan brand awareness. Diharapkan penelitian ini dapat memberikan wawasan kepada praktisi pemasaran mengenai pilihan strategi pemasaran yang lebih efektif dalam membangun kesadaran merek. Selain itu, penelitian ini dapat menyumbangkan pemikiran tambahan dalam bidang periklanan dan komunikasi pemasaran dalam era digital.
PERANCANGAN SISTEM APLIKASI PENGADUAN WARGA BERBASIS ANDROID DI KELURAHAN CIMONE
Authors: Prayogo Prayogo
Published: February 2024

As the use of information technology advances, every government agency should try to improve the quality of its services. One of them is in the complaint service which is a place or forum for the public to express complaints, grievances, aspirations and appreciation of the Government's performance in accordance with Presidential Regulation Number 76 of 2013 concerning the management of public service complaints. This research takes a case study in Cimone Village, where there is no system for managing citizen complaints, especially in Cimone Village. To anticipate residents spreading their complaints in the wrong place, without knowing how to submit complaints correctly. For this reason, there is a need for an Android-based citizen complaint application system as a space for aspirations that can be accessed easily. The application design uses the Waterfall method, built using Android Studio, the Java programming language and Firebase as the database, and the system testing uses black box testing so that the Android-based citizen complaint application system fulfills the aspirations of Cimone sub-district residents in a relevant and flexible manner.
Analisis Yuridis Pembubaran Perseroan Terbatas Ampana Mandiri Property oleh Kejaksaan (Studi Putusan nomor 29/Pdt.P/2020/PN.POSO)
Authors: Salsabilla Nenden Sonia , Suryono Ahmad
Published: February 2024

Undang-undang memberikan tempat atau legalitas kepada kejaksaan dalam peradilan dalam proses per-bubaran peseroan terbatas atas dasar pelanggaran kepentiingan umum atau melanggar peraturan perun-dang-undangan. Namun, terdapat pada Putusan Kejaksaan Nomor 29/Pdt.P/2020/PN.Poso, dirasa memiliki kendala terhadap arti melanggar kepentingan umum tersebut. Hal yang menjadi pokok problematika pada tulisan ini, dimana untuk mengetahui pertimbangan hakim dalam penetapan pembubaran PT. Ampana Mandiri Property Nomor 29/Pdt.P/2020/PN.Poso khususnya terkait frase kepentingan umum. Dalam penulisan ini, peneliti menggunakan jenis penelitian yuridis normatif dengan menggunakan pendekatan peraturan perundang-undangan, kasus, dan kon-septual. Kejaksaan berwenang mengusulkan perbubaran peseroan terbatas karena pelanggaran kepentiingan umum dalam Pasal 146 ayat (1) Undangn-Undang Nomor 40 Tahun 2007 tentang peseroan terbatas. Ketika jaksa mengajukan permohonan untuk membubarkan perusahaan, undang-undang mengharuskan dia untuk membuktikan bahwa kepentiingan umum perusahaan telah dilanggar.
Dissecting the Structure of Joyce Kilmer's 'Trees'
Authors:   Carlos Hilado Memorial State University, G. Villanueva Lindlee , D. Chua Marijo ,   Talisay City, Negros Occidental, Philippines
Published: February 2024

This literary research aimed to analyze the poem of Joyce Kilmer’s Trees. This textual analysis utilizes a structural approach that explores binary oppositions in the content. A structural analysis uncovered the deep structures and underlying patterns that inform literary texts. It also identified recurring themes, motifs, and narrative structures that contribute to the overall meaning of a work. The elements include light and darkness, strength and fragility, rootedness and freedom. It sought to find the meaning of the text in-depth by identifying the relationship between the binary oppositions. The result revealed that the use of vivid imagery and contrasting ideas highlighted the complexity and interconnectedness of the natural world.
Development of ICARE-Based Physics Teaching Materials to Improve Students' Critical Thinking Ability
Authors:   Physics Education, Postgraduate Program, Makassar State University, Makassar, Indonesia., Jumriani Jumriani , Arafah Kaharuddin ,   Physics Education, Postgraduate Program, Makassar State University, Makassar, Indonesia., Khaeruddin Khaeruddin ,   Physics Education, Postgraduate Program, Makassar State University, Makassar, Indonesia.
Published: February 2024

Research on the development of ICARE-based teaching materials aims to: 1) analyze the results of the content validity of ICARE-based physics teaching materials which meet valid criteria, 2) analyze practitioners' assessments of ICARE-based physics teaching materials, 3) analyze the effectiveness of ICARE-based teaching materials. The test subjects of this research were 28 students of class XI Science at Sma Muhammadiyah 1 Unismuh. Research method with 4D models. The instruments used in this research were validation sheets, practitioner assessment questionnaires, and test instruments for students' critical thinking abilities. Practicality criteria are seen from practitioners' assessments of teaching materials, and effectiveness criteria are seen from the average percentage of students' critical thinking ability improvement scores. Based on the results of the analysis, the following conclusions were obtained: (1) ICARE-based teaching materials which were developed based on expert assessment using Aiken's V index analysis were declared valid and suitable for use with slight revisions; (2) ICARE-based physics teaching materials in terms of teacher responses were in the category Very good; (3) the effectiveness of ICARE-based physics teaching materials analyzed using N-gain obtained an average value of 0.50, which is included in the medium category, meaning there is an increase in students' critical thinking abilities so it can be said that the ICARE-based physics teaching materials developed are effective and can improve abilities. students' critical thinking.
PEMBUATAN SABUN CUCI TANGAN CAIR BERBASIS BERBAGAI MERK MINYAK ZAITUN DENGAN PENAMBAHAN MINYAK ATSIRI SEREH WANGI (CYMBOPOGON WINTERIANUS JOWITT)
Authors: Aisyah Siti , Raja Pada Mulia , Purwanto Heri
Published: February 2024

Soap is a product that functions as a cleaner and wash. Hand washing soap in the form of a solution (liquid) is preferred because it looks more attractive and is more practical. Liquid Soap Liquid soap is made through a saponification process using oil and using alkali (KOH). Olive oil contains α-tocopherol (vitamin E) and β-carotene which function as antioxidants. The use of essential oils is good in making perfume, cosmetics, medicines, soap and fragrances, essential oils function as a fixative. The essential oils used are generally patchouli oil, citronella oil, vetiver oil and sandalwood oil. This research aims to make liquid hand washing soap based on various brands of olive oil with the addition of citronella essential oil. The liquid hand washing soap produced is in accordance with SNI, where olive oil-based liquid hand washing soap with brands "B" and "C" has a normal pH, namely 7.03 and 6.98, while brand "A" has a slightly acidic pH, namely 6.01 and brand “D” has a slightly alkaline pH, namely 7.95. The specific gravity produced by brand "A" is 1,027 g/ml, brands "B", "C" and "D" are 1,024 g/ml, 1,096 g/ml and 1,099 g/ml. The liquid hand washing soap based on olive oil with the addition of citronella essential oil produced does not contain microbes with the clean power of brand "B" being higher at 191 FTU turbidity compared to brand "A" at 173 FTU turbidity, brand "C" at 166 FTU turbidity and the “D” brand only has 122 FTU turbidity.
Long term effects of childhood trauma and abuse: narrative on functional neurological disorder
Authors: Ilyas Uzma , Khanum Aliza , Fatima Kalsoom
Published: February 2024

Functional neurological disorder is a condition in which a person experiences physical symptom that cannot be fully explained by a medical condition. In Pakistan, domestic violence as well as emotional, physical and sexual abuse in children are prevalent. Despite legal and social support for victims, stigmatisation regarding seeking psychological help complicates the challenge. Some of the research culminated that patients with fneurological disorder reported high level of sexual abuse and trauma. The symptomatology of functional neurological disorder is being ignored in Asian countries due to indigenous factors like poverty, lack of information on reporting abuse, poor law-enforcement and victim blaming. Functional neurological disorder can be manifested in various ways in the human body, such as blindness, paralysis, dystonia, swallowing difficulties, difficulty walking, motor symptoms affecting limbs, 
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Implementasi Istishab Sebagai Perkembangan Hukum Islam
Authors: Ihza Ahmad , Nurlaeli Ida
Published: February 2024

The dimension of Islamic law can be achieved by emphasizing the theory of benefit as the main consideration for determining a law. One of them is an effort to review istishab as an argument for determining the law, namely by determining the status of the origin. Sometimes the origin is permissible, free from demands, and sometimes it is permanent. Istishab is a method of ijtihad. Ijtihad is the inner dynamic for the birth of change to maintain the comprehensiveness of Islamic law. Istishab itself is a source of law that is debated by scholars and whether istishab itself is included as a proof or not. The first opinion says hujjah as a legal determination, the second istishab is not used as a proof in making law, the third is a proof in determining new problems. Istishab is also widely applied in various cases, both in the fields of family law, criminal, civil and economic law. More than that, the important value of the application of istishab is the principle of law in Indonesia (the principle of presumption of innocence), the principle of legality and the principle of Nullum delictum nulapoena sine praevia leg poenali makes it important to be studied further.
Pengaruh Digital Marketing, Product Quality Terhadap Purchase Intention Dengan Brand Image Sebagai Variabel Intervening Pada Produk Pakaian Uniqlo
Authors: Lusi Widhi Aningrum  , Nur Achmad
Published: February 2024

Tujuan dari penelitian ini adalah untuk mengkaji dan menganalisis pengaruh digital marketing, product quality terhadap purchase intention dengan brand image sebagai variabel intervening pada produk pakaian Uniqlo. Penelitian ini menggunakan data primer yang didapatkan dari hasil penyebaran kuesioner melalui google form kepada 144 orang generasi Y dan Z  yang mengetahui produk pakaian Uniqlo. Data diolah menggunakan SmartPLS 3.0. Hasil penelitian menunjukkan digital marketing berpengaruh positif dan signifikan terhadap purchase intention, digital marketing tidak berpengaruh positif dan signifikan terhadap brand image, product quality berpengaruh positif dan signifikan terhadap purchase intention, product quality berpengaruh positif dan signifikan terhadap brand image, purchase intention berpengaruh positif dan signifikan terhadap brand image, brand image tidak memediasi pengaruh digital marketing terhadap purchase intention, brand image mampu memediasi secara positif dan signifikan terhadap pengaruh product quality terhadap purchase intention.
Environmental Initiatives to Improve Well-being for Impoverished Americans
Authors: Tan Vivian , Homan Mackenzie
Published: February 2024

Impoverished communities in America continue to be left behind despite the nation's industrialization and improving quality of life. In 2021, the United States Census Bureau reported that 11.6% of Americans still lived in poverty (Creamer et al., 2022). Living at an economic disadvantage, individuals in poverty often cannot afford basic necessities and meet satisfactory living standards. Among these challenges is environmental inequality in which impoverished Americans can lack access to vegetated areas or well-maintained environments (Sicotte, 2013 & Erickson, 2016). The ramifications of this challenge contribute to heightened susceptibility to both mental and physical health complications, including but not limited to depression, anxiety, and heat-related fatalities (Ridley 2020 & EPA, n.d.). To combat the health crisis, this review aims to explore how environmental initiatives – such as green spaces, outdoor community events, and environmental justice – are able to improve the well-being of impoverished communities. I analyze current literature and find that increased interactions with natural environments boost well-being. Additionally, I evaluate active environmental initiatives in America and relate their potential to serving low-income communities. From analysis, it is evident that fostering a deeper connection with the natural environment holds promise for enhancing the holistic wellness of impoverished communities. Future endeavors in public and non-profit sectors should focus on achieving the successful incorporation of environmental initiatives in low-income neighborhoods.
NEUROPEDAGOGIA E NEURODIDÁTICA NA IDENTIFICAÇÃO PRECOCE DE TRANSTORNOS NO DESENVOLVIMENTO COGNITIVO DE CRIANÇAS E ADOLESCENTES
Authors: Oliveira Jádia Elane
Published: February 2024

A neuropedagogia é uma área que se dedica ao estudo das relações entre o cérebro, o desenvolvimento humano e a aprendizagem. Por meio de uma abordagem multidisciplinar, a neuropedagogia busca entender como o cérebro processa informações e como isso pode afetar o processo de ensino e aprendizagem. O objetivo geral deste estudo é compreender a importância da neuropedagogia e da neurodática na identificação precoce de transtornos que afetam o desenvolvimento cognitivo e escolar de crianças e adolescentes, com foco no diagnóstico e intervenção. Um dos principais objetivos da neuropedagogia é identificar e intervir precocemente em transtornos que possam afetar o desenvolvimento cognitivo e escolar de crianças e adolescentes. A metodologia foi a revisão de literatura descritiva, realizada nas bases de dados multidisciplinares e nas bases específicas da área da saúde e farmácia. As bases de dados utilizadas foram: Scientific Eletronic Library Online (SCIELO), ferramenta Google Acadêmico. Esta publicação procura definir os pressupostos teóricos da neuropedagogia. Esta é a primeira e essencial etapa do processo de investigação, uma vez que a literatura científica carece deste panorama científico da realidade, a partir do qual os pedagogos seriam capazes de conceber a investigação pedagógica e neurobiológica.
Experiencia en el uso de microrregistro para estimulación cerebral profunda del núcleo subtalámico en pacientes con enfermedad de Parkinson
Authors: Bastidas Benavides José Libardo , Serrano Ortiz Javier Mauricio , Rueda Acevedo Mauricio , Bareño Silva José
Published: February 2024

Introducción: El uso de Microregistro (MR) para colocación de electrodos de Estimulación Cerebral Profunda (ECP) continúa siendo debatido en la corrección del blanco preoperatorio, complicaciones y resultados. Describimos la experiencia de su uso en el mapeo del Núcleo Subtalámico (NST) en pacientes con Enfermedad de Parkinson (EP).Materiales y métodos: Se realizó un estudio observacional, retros- pectivo de pacientes con EP tratados desde 2009 hasta 2012. Se describió la discrepancia entre la planeación inicial y la definitiva a través de la suma de los vectores de desviación en los planos X y Y, complicaciones y porcentaje de mejoría, correlacionado con varia- bles demográficas, anatómicas y de la evolución de la enfermedad.Resultados: Se trataron 43 pacientes, se implantaron 81 electrodos. La desviación media del blanco preoperatorio fue 2,57 mm. El 71,6% de los electrodos tuvieron desviación > 2 mm, 40,7% > 3 mm y el 16% > 4 mm. Ninguna variable se asoció con mayor desviación, con el número de trayectos realizado ni con diferencias en mejoría del UPDRS III. Sólo un paciente presentó hemorragia.Conclusiones: El uso del MR permitió una corrección significativa del blanco en un amplio porcentaje de casos, la cual podría relacionarse con un mejor resultado clínico. No se asociaron factores al grado de desviación, la frecuencia de complicaciones serias es baja.
LISTRIK DAN PENGARUHNYA TERHADAP PERTUMBUHAN EKONOMI DI PROVINSI MALUKU
Authors: Sapthu Andre
Published: February 2024

Electricity has a very important role in influencing a country's economic growth. High electricity consumption is often an important indicator of the level of industrialization and technological progress in an economy. In this research, we will examine theoretically the influence of electricity consumption and labor variables on economic growth. To analyze the relationship between variables in the research model, we use a regression equation model using annual data. The research results show that the electricity consumption variable significantly influences economic growth, while labor does not significantly influence economic growth and has a unidirectional relationship. Increased productivity supported by a reliable electricity supply can increase efficiency in the production of goods and services, trigger growth in the industrial sector, and create jobs. Strong electricity consumption also encourages investment in energy infrastructure that can stimulate economic growth.
PENGARUH LAYANAN PERMODALAN DIGITAL TERHADAP KINERJA UMKM
Authors: Gainau Paskanova Christi , Kilay Trisye Natalia
Published: February 2024

The aim of this research is to examine the influence of digital capital services represented by market aggregator variables on MSME performance. Market aggregator examines the aspect of access to information related to capital for business actors. The research used a survey method through observation and distributing questionnaires to business actors in Ambon City. Samples were taken based on purposive sampling technique. The research results show that digital capital services can significantly boost the performance of MSMEs. Business actors who utilize market aggregator platforms to access capital information encourage them to obtain quality information related to capital decision making so that ultimately it supports business actors to achieve satisfactory business performance. These results also have an impact on the economic sector in general, where when business actors gain access to adequate capital, sales and profit levels can increase. If sales and profits increase then in the long term the business level can increase to the next level. Increasing the level of business certainly encourages an increase in state revenues through taxes, employment, and an increase in gross domestic product (GDP).
Severity of muscle impairment and its progression assessed using musculoskeletal magnetic resonance imaging and diffusion tension imaging in 78 boys with Duchenne muscular dystrophy: a retrospective study
Authors: Sane Hemangi , Nivins Samson , Paranjape Amruta , Gokulchandran Nandini , Badhe Suvarna , Varghese Ritu , Badhe Prerna , Sharma Alok
Published: February 2024

Purpose

Duchenne muscular dystrophy (DMD) is the most common and severe form of muscular dystrophy. Current diagnostic tests like genetic testing, needle electromyography, and muscle biopsy are either not easily available or invasive, and they are impractical for assessing disease progression and treatment outcomes. Therefore, there is a need for a non-invasive and accurate investigative modality for DMD. In recent years, musculoskeletal magnetic resonance imaging (MRI-MSK) along with fractional anisotropy (FA) and diffusion tensor imaging (DTI) have become major non-invasive tools.

Material and methods

T1-weighted MRI-MSK and FA measures of DTI of 78 DMD patients were retrospectively studied to identify the distinct pattern of muscle involvement and fatty infiltration as age and/or disease progresses. Correlation analysis was performed between MRI-MSK grade score vs. age, muscle strength, and Vignos scale. Spearman’s rank correlation coefficient was used.

Results

As age increased, the MRI grade score and Vignos score increased. There was a statistically significant high positive correlation between MRI-MSK grade score and age, and low positive correlation with Vignos scores. With increasing age, the muscle strength on manual muscle testing (MMT) and FA value decreased. There was high negative correlation with muscle strength on MMT and low positive correlation between FA values and MMT score.

Conclusions

On T1-weighted MRI, a distinct pattern, extent, and distribution of lower limb muscle involvement can be seen. MRI-MSK grade score worsens with progressing age, reducing strength, and increasing functional impairment. FA alone may not be an accurate marker in assessing progression of DMD. MRI-MSK and other DTI measures should be further explored as diagnostic and prognostic tools for DMD.
LITERACY FROM A LITERACY PERSPECTIVE
Authors: Dias Dos Santos Deusiane
Published: February 2024

Historically, in our educational context, the work of teachers, especially recent graduates, has faced several challenges, especially when it comes to literacy in the initial grades of elementary school. A teacher who begins his career in literacy usually faces large classes and needs to deal with students who have different knowledge and experiences. Many students often have difficulties acquiring reading and writing skills and need interventions suited to their real needs. This article aims to present reflections/discussions/analyses about literacy for teaching reading in early grades. In terms of challenges, we observed the following results: the weakening of initial training, which ends up distancing theory from practice; classrooms with many students; internships carried out with gaps in supervision; curricula with more emphasis on theories than on literacy practices/methodologies; the lack of planning, or even a political pedagogical project, that guides the newly graduated literacy teacher in their work; in addition to the discontinuity of continuing education policies.
Amnios con cobertura antibiótica: eficacia en pacientes sometidas a conización
Authors:   Hospital Central de San Cristóbal. Táchira. Venezuela, Izquierdo León Haelka , Ardila Anais , González Blanco Mireya
Published: February 2024

Objective: To compare the evolution of healing in patients in whom amnion with antibiotic coverage was applied, with another group in which it was not applied, after cervical conization performed in cervical pathology consultations of the San Cristobal Central Hospital, between February and May 2023. Methods: Experimental, randomized, longitudinal comparison. It included 66 patients, randomly divided into two groups. Group 1: in which amnion was applied (n = 36/54.5 %); Group 2: no treatment (n = 30/45.5%). The researcher prepared the amnions of placentas obtained by cesarean section or vaginal delivery, in the operating room. Informed consent was obtained from both donors and recipients. Results: On day 14, none of the patients in the group 1 had epithelialization. In the group 2, one patient (2.7%) had 50% epithelialization and 35 (94.6%) had reached 100% (p < 0.001). Epithelialization was total in 13.3% of the first group and 94.6% of the second group (Odds Ratio of 227 (95% CI: 24.0 to 2157.0; p < 0.001). There were no cases of cervical infection. Five patients (16.7%) in the group 1 and one in the group 2 (2.8%) had ectopias (p = 0.051). There was no association between complete or partial epithelialization and clinical characteristics (p ˂ 0.05). Conclusion: Amnion with antibiotic coverage is associated with better healing outcomes in conized patients. Its effectiveness as a medical therapy was proven when placed on the surgical wound. Keywords: Amnion, Epithelion, Placenta.
Rotura prematura de membranas: diagnóstico y manejo
Authors:   Unidad de Perinatología Dr. Freddy Guevara Zuloaga, Hospital Universitario de Caracas., Araujo-Vargas Kenny , León-Villavicencio Luisa , Villegas-Márquez Carlos
Published: February 2024

Premature rupture of membranes is classified according to gestational age: term (from 37 weeks of gestation), and preterm (before 37 weeks). This is subdivided into near-term (34 and less than 37 weeks), far from term (24 to 34 weeks), and previable (before 24 weeks). It affects 8% of pregnancies; Preterm: 2% to 4% of singleton pregnancies, 7% to 20% of twins. It carries risks such as chorioamnionitis and normoinserted placental abruption. Intra-amniotic infection occurs in 15% to 35% of cases. Timely diagnosis and appropriate management are vital to reduce associated morbidity and mortality. The aim of this review is to address the diagnosis and management of premature rupture of membranes according to gestational age. Keywords: Premature rupture of membrane, preterm birth, corioamnionitis.
Tumor de células de la granulosa tipo juvenil tras la menopausia
Authors:   Complejo Asistencial Universitario de Palencia. España, Cortiñas Díez Inés , Berzal Cantalejo María Fernanda , López-Menéndez Arqueros María
Published: February 2024

Granulosa cell tumors are rare ovarian tumors. There are two histological types: adult and juvenile. Juvenile granulosa cell tumors account for 5%, with only 3% occurring in people over 30 years of age. Given the suspicion, the definitive intraoperative diagnosis is complex given its rarity and its easy confusion with other ovarian neoplasms. The cystic pattern with immature granulosa cells, with frequent mitosis, the absence of Call-Exner bodies and the immunocystic study confirm this. Its low prevalence makes it difficult to diagnose. The stage of the disease is the most important prognostic factor, and complete resection is essential. The role of complementary therapy is not well established, and the available studies include only a minimal number of cases, which do not differentiate between adult women. Adequate follow-up for the early detection of a possible late recurrence is a clinical challenge. Keywords: Granulosa cell tumor, Juvenile granulosa cell tumor, Ovarian neoplasms, Menopause.
O trabalho etnográfico de campo e suas implicações na perspectiva dos estudos das sexualidades
Authors: De Jesus José Welington
Published: February 2024

The aforementioned study is a literature review on the discussions held in the field of ethnographic work, spanning from classical anthropological studies with influential figures like Bronislaw Malinowski, James Clifford Geertz, and Marshall Sahlins, to contemporary anthropological studies that significantly impact anthropological practices, particularly in the realm of ethnographic work. Our focus is on examining the contributions of these studies to work and research in the field of sexualities. We aim to explore how these studies have shaped and continue to shape the understanding of realities related to the experiences of diverse sexualities