bluuebunny/crossref_metadata_2025 huggingface dataset:
A New Class of Fractional Cumulative Residual Entropy - Some Theoretical Results
Authors: Benmahmoud Slimane
Published: March 2023

In this paper, by differentiating the entropy’s generating function (i.e., h(t) = R SX̄F tX (x)dx) using a Caputo fractional-order derivative, we derive a generalized non-logarithmic fractional cumulative residual entropy (FCRE). When the order of differentiation α → 1, the ordinary Rao CRE is recovered, which corresponds to the results from first-order ordinary differentiation. Some properties and examples of the proposed FCRE are also presented.
Ensino de Ciências e Educação em Saúde: análise da abordagem sobre Saúde Preventiva no Ensino Fundamental II no olhar dos docentes
Authors: Ramos Lutz Mauricio , Santos dos Santos Caroline , De Oliveira Luciano
Published: March 2023

Diante da importância da escola na formação de cidadãos, é fundamental que vários temas sejam abordados, dentre eles saúde. Normalmente, essa abordagem é feita por meio de professores da disciplina de Ciências. Sendo assim, esta pesquisa tem por objetivo analisar a implantação do ensino de Saúde Preventiva na disciplina de Ciências do Ensino Fundamental II, em escolas da rede estadual de ensino, situadas no município de Alegrete/RS, assim como compreender a percepção docente sobre a forma de abordagem desse tema e receptividade dos alunos acerca da Educação em Saúde na escola. A pesquisa, classificada como qualitativa e experimental, foi realizada por meio de questionários encaminhados aos docentes, abordando questões abertas sobre os temas Educação em Saúde e Saúde Preventiva. Os dados coletados foram analisados por meio da Análise de Conteúdo, em que foi possível identificar que os docentes participantes trabalham com este tema em suas aulas e têm bons resultados. Entretanto, relatam que existem lacunas relativas à falta de abordagem de Educação em Saúde e Saúde Preventiva, tanto no curso de Licenciatura em Ciências Biológicas como na formação continuada de professores. Alterações nas ementas dos cursos de Licenciatura em Ciências Biológicas, capacitações com o objetivo de melhorar a proposta didática docente sobre essas temáticas, a promoção da interdisciplinaridade dessas temáticas com as demais disciplinas, seguindo o que é recomendado pela Base Nacional Comum Curricular (BNCC), no futuro, são ações que podem levar a resultados mais satisfatórios e promissores para o desenvolvimento de uma Educação Básica de qualidade.
PENGARUH HASIL BELAJAR TERHADAP MINAT BERWIRAUSAHA PADA PROGRAM PENDIDIKAN KEWIRAUSAHAAN
Authors: Sadewo Yosua Damas , Purnasari Pebria Dheni , Beni Sabinus
Published: March 2023

Penelitian dilakukan dengan tujuan untuk mengetahui pengaruh hasil belajar dengan minat dalam berwirausaha di Program Studi Kewirausahaan, sehingga hasil dari penelitian ini dapat menunjukkan apakah hasil belajar pada Program Studi Kewirausahaan dapat menjadi salah satu faktor tumbuhnya minat dalam berwirausaha. Jenis penelitian ini menggunakan pendekatan kuantitatif. Adapun penelitian ini dilakukan di lingkungan STIM Shanti Bhuana, dengan subjek penelitian adalah mahasiswa STIM Shanti Bhuana Program Studi Kewirausahaan angkatan 2017 yang berjumlah 27 orang. Analisis pengumpulan data  menggunakan tes, tes dijadikan alat untuk mengukur hasil belajar mahasiswa terkait wawasan kewirausahaan di Program Studi Kewirausahaan, sedangkan data mengenai minat berwirausaha diambil dengan menggunakan angket pada responden yang sama. Setelah data diperoleh, maka dilakukan rekap dan analisis menggunakan uji pengaruh. Hasil penelitian menunjukkan adanya pengaruh antara hasil belajar Kewirausahaan terhadap minat dalam berwirausaha yang signifikan dengan besarnya pengaruh 36,3%. Berdasarkan hasil ini, maka dapat diketahui bahwa tumbuhnya minat dalam berwirausaha dapat dipengaruhi dengan nilai hasil belajar yang baik, oleh karena itu untuk mendorong hasil belajar yang baik perlu proses pembelajaran yang baik, sehingga satu dengan yang lain saling terkait.
Türkiye’de Avrasyacı Siyasal Söylemler Bağlamında Mustafa Kemal Atatürk Dönemi Türk Dış Siyaseti
Authors: ERDEM Demirhan Fahri
Published: March 2023

Bu çalışma, Türkiye’de 1990’lardan itibaren ortaya çıkmaya başlayan Avrasyacı siyasal söylemlerin savunduğu dış siyasetin köklerinin, Mustafa Kemal Atatürk dönemi Türk dış siyasetinde bulunup bulunmadığını araştırmayı amaçlamıştır. Makalede Mustafa Kemal’in ulusal kurtuluş mücadelesine önderlik etmeye başladığı 1919’dan, ölümüyle iktidarının son bulduğu 1938’e kadar olan zaman dilimindeki Türk dış siyasetine odaklanılmıştır. Nitel araştırma yöntemlerinin kullanıldığı çalışmada, Mustafa Kemal’in sözleri ve uygulamaları dâhil olmak üzere elde edilen veriler, tarihsel bağlamda döneme hâkim zihniyet de göz önünde bulundurularak, Avrasyacı siyasal söylemlerin parametreleri çerçevesinden çözümlenmiştir. Türkiye’deki Avrasyacı siyasal söylemlerin çoğuna hâkim olan ortak bir takım parametrelerin, Mustafa Kemal dönemi Türk dış siyasetinin de temel özellikleriyle örtüştüğü anlaşılmaktadır. Türkiye'deki Avrasyacı siyasal söylemlerin çoğu, antiemperyalizm, tam bağımsızlık, uluslararası işbirliği, Türkiye’ye önderlik rolü yükleme ve Batı karşıtlığı gibi ortak parametrelerde birleşmektedir. Mustafa Kemal dönemi Türk dış siyaseti de; bir takım parametreler için vurgu yoğunluğu içinde bulunulan konjonktüre göre değişse de, kararlı biçimde tüm bu parametrelere uygun karakterde olmuştur. Dolayısıyla Türkiye’deki Avrasyacı siyasal söylemlerin savunduğu dış siyaset için, Türkiye’nin yeterli tarihsel tecrübe mirasına sahip olduğu söylenebilir.
Sera Gazı Emisyonunun Tarımda İşgücü Verimliliğine Etkisi: Avrupa Birliği Ülkeleri Bağlamında Bir Analiz
Authors: ÇEVİK Ömer Can , YEŞİLKAYA Fatma , KARAMAN Nursel
Published: March 2023

İklim değişikliğinin dünyada çeşitli alanlarda yarattığı sorunlar ve bu sorunlara yönelik çözüm önerileri son yıllarda akademik camiada önemle üzerinde durulan konulardan biri haline gelmiştir. Bu doğrultuda çalışmada, iklim değişikliğinin önemli göstergelerinden biri olan sera gazı emisyonunun tarımda işgücü verimliliğine etkisi Avrupa Birliği’nin 1996-2019 verilerinden hareketle zaman serisi analizi yöntemi ile incelenmiştir. Yapılan analizlerle tarımda işgücü verimliliği ile sera gazı emisyonunun eşbütünleşik yani uzun dönemli ilişki içerisinde olduğu ve değişkenler arasında çift yönlü nedensellik ilişkisi olduğu tespit edilmiştir. Analiz kapsamında ayrıca gerçekleştirilen etki-tepki analizi ile sera gazı emisyonundan kaynaklanan bir etkiye tarımda işgücü verimliliğinin gösterdiği tepkinin zaman içerisinde azalan oranda değiştiği fakat analizin gerçekleştirildiği süreç içerisinde sıfıra yakınsamadığı, tarımda işgücü verimliliğinde yaşanan bir etkinin ise sera gazı emisyonunda negatif bir tepki yarattığı ve yine bu tepkinin analizin gerçekleştirildiği 24 yıllık süreç içerisinde sıfıra yakınsamadığı yani devamlılık taşıdığı gözlenmiştir. Son olarak gerçekleştirilen varyans ayrıştırması sonucunda değişkenlerde ortaya çıkan değişimlerin diğer değişkenden kaynaklanan kısmının zaman içerisinde bir artış gösterdiği fakat değişimlerin büyük ölçüde değişkenlerin kendilerinden kaynaklandığı tespit edilmiştir.
Investigation of otolith asymmetry in Mulloidichthys flavolineatus and Parupeneus forsskali (Perciformes: Mullidae) from Egypt’s Hurghada fishing harbour on the Red Sea
Authors: Jawad Laith , Qasim Audai , Farrag Mahmoud M. S. , Osman Alaa , Samy-Kamal Mohamed , Mehanna Sahar , Abdel-Maksoud Yassein
Published: March 2023

The current study aims to calculate and assess the asymmetry of the two goatfish species, Yellowstripe goatfish Mulloidichthys flavolineatus (Lacepède 1801) and Red Sea goatfish, Parupeneus forsskali (Fourmanoir & Guézé 1976) collected from Hurghada fishing harbour, Egypt. The asymmetry valuation for M. flavolineatus and P. forsskali is imperative to demonstrate the impact of asymmetry on the larvae settlement in this vital fishing ground. Asymmetry was calculated for the saccular otolith (Sagittae) biometry, namely length, width, and mass. The results showed that the otolith height had a lower asymmetry value than the otolith length for the two goatfish species inspected. No relationship between the asymmetry value of otolith length and width and total fish length was observed. Both goatfish species’ calculated otolith mass asymmetry was higher than that of many teleost fish species.
The Analysis Of The Effect Of Emotional Intelligence On Understanding Level In Programming Algorithm Learning
Authors: Sri Handani Widiastuti  , Nur Imansyah  , Abdul Zain
Published: March 2023

The course Algorithms and Programming in the Informatics Engineering study program is given in the first and second semesters, as this course is a scientific course that serves as a basis for advanced programming courses in higher semesters. It is often the case that intelligent graduates obtain good academic grades during their studies and become outstanding students, but when working in their field of expertise, their performance is not as good as graduates who had lower academic grades. Success is not only determined by intellectual intelligence (IQ), but also by other types of intelligence. Intellectual intelligence or cognitive intelligence is one type of intelligence, while non-intellectual intelligence includes other types of intelligence outside of cognitive intelligence. One of this non-intellectual intelligence is emotional intelligence. Intellectual intelligence and non-intellectual intelligence play equally important roles in supporting individual success.

This research discusses the analysis of the effect of emotional intelligence on the level of understanding of algorithms and programming using the linear regression method implemented with an application. The sample taken is students of the Informatics Engineering study program in the third and fourth semesters. With the results of the influence of emotional intelligence on the understanding of Algorithms and Programming, it can provide a solution to improve students' understanding of the Algorithms and Programming course and other computer courses in the scientific field of the Informatics Engineering study program. The application is created using the Python programming language
Neurotoxic Effects of Diosmetin on SH-SY5Y Cells: Role of Nrf2/ARE Antioxidant Response Element and Apoptosis Signaling Pathways
Authors: Çınar Ayan İlknur , Güçlü Ebru
Published: March 2023

Neuroblastoma is the most common extracranial solid neoplasm in childhood, originating from the nerve cells of the sympathetic nervous system. Diosmetin, the aglycone of the flavonoid glycosides diosmin, is abundant in many medicinal
plants. Studies have shown that diosmetin has anticarcinogenic and protective effects in many different cancers. However, its effects on neuroblastoma have not yet been clarified. In our study, we aimed to evaluate the effects
of diosmetin on Nrf2/ARE antioxidant pathway mediated apoptosis in SH-SY5Y cell line. The cytotoxic effect of diosmetin in SH-SY5Y cells was evaluated by XTT cell proliferation assay. Nine different concentrations of diosmetin
(2.5-5-10-20-30-40-50-75-100 μM) were applied to SH-SY5Y cells for 24 and 48 hours. The cytotoxic IC50 dose of diosmetin was determined as 8.9 µM at 24 hours. Colony formation assay was performed to evaluate the effect of diosmetin
on the colony forming abilities of neuroblastoma cells and it was determined that diosmetin significantly reduced colony formation. Annexin V/7-AAD assay and Real time quantitative PCR analysis were also performed to evaluate whether
diosmetin suppressed cell viability through apoptosis. According to Annexin V/7-AAD assay results, it was determined that diosmetin inhibited cell viability by inducing both early and late apoptosis. When the expressions of apoptosis
and Nrf2/ARE-related genes were evaluated at the mRNA level, it was determined that CASP7, CASP8, CYCS, BAX and FADD increased significantly, while NRF2, KEAP, NQO1, SOD2 and SOD3 decreased. The results suggest that diosmetin induces
apoptosis by suppressing the Nrf2/ARE pathway in SH-SY5Y cells.
Manajemen Pemupukan Tanaman Kelapa Sawit (Elaeis guineensis Jacq.) pada Tanaman Menghasilkan di Kebun Petapahan, Kampar, Riau
Authors: Afifuddin  , Hariyadi  , Suwarto
Published: March 2023

Kelapa sawit (Elaeis guineensis Jacq.) merupakan salah satu komoditas perkebunan yang menghasilkan minyak nabati. Salah satu faktor terpenting dalam pemeliharaan kelapa sawit adalah pemupukan untuk meningkatkan produktivitas. Penelitian dilaksanakan pada bulan Januari 2021 di Kebun Petapahan PT Peputra Masterindo, Kampar, Riau. Tujuan penelitian ini adalah menganalisis manajemen pemupukan tanaman kelapa sawit di Kebun Petapahan. Pengamatan aspek khusus dilakukan terhadap manajemen pemupukan di lapangan berdasarkan 5 prinsip tepat (tepat jenis, tepat takaran, tepat tempat, tepat waktu, dan tepat cara aplikasi) dan gejala defisiensi unsur hara pada tanaman kelapa sawit. Hasil pengamatan terhadap prinsip 5T menunjukkan bahwa aplikasi pemupukan di Kebun Petapahan sudah sesuai dengan rekomendasi perusahaan dengan ketepatan 100%. Ketepatan dosis pupuk Borate adalah 97.78%. Ketepatan pemupukan cukup baik dengan persentase rata-rata 91.11%. Akurasi penempatan pada pupuk KCL sebesar 152.81 cm. Namun pada prinsipnya ketepatan takaran pupuk KCL masih dibawah standar aplikasi perkebunan yaitu 90.56%. Sedangkan pada pengamatan ketepatan waktu aplikasi pupuk Urea, Rock phosphate, dan Dolomit masih belum sesuai dengan waktu aplikasi yang direkomendasikan. Defisiensi unsur hara menunjukkan bahwa di Kebun Petapahan terdapat 12% tanaman yang mengalami gejala defisiensi unsur hara Kalium (K).

Kata kunci: defisiensi hara, pupuk, rekomendasi, tepat pemupukan
Kajian Jumlah Benih Per Lubang Tanaman terhadap Pertumbuhan dan Produksi Tanaman Jagung Manis (Zea mays saccharata. Sturt)
Authors: Regyta Savirha , Ritonga Arya Widura , Permatasari Okti Syah Isyani
Published: March 2023

Produktivitas nasional jagung manis masih tergolong rendah dengan potensi hasil yang tidak stabil, sedangkan kebutuhan masyakarat terus meningkat. Produktivitas dapat ditingkatkan melalui penggunaan varietas unggul dan teknik budidaya yang tepat salah satunya jumlah benih per lubang. Penelitian ini bertujuan mengetahui pengaruh varietas, jumlah benih per lubang, serta interaksi jumlah benih per lubang dan varietas terhadap pertumbuhan dan produksi tanaman jagung manis. Penelitian ini dilaksanakan dari bulan Agustus hingga November 2021 di Kebun Percobaan Leuwikopo, Dramaga, Bogor, Jawa Barat. Penelitian ini menggunakan rancangan kelompok lengkap teracak (RKLT) pola tersarang, dengan petak utama jumlah benih per lubang tanam dan anak petak 8 varietas jagung manis. Hasil penelitian menunjukkan bahwa jumlah benih per lubang berpengaruh nyata terhadap karakter-karakter agronomis seperti, panjang daun, lebar daun, panjang tongkol, bobot tongkol berkelobot, bobot tongkol tanpa kelobot, panjang tangkai tongkol, padatan terlarut total, dan produktivitas. Serta terdapat interaksi yang tidak nyata antara pemakaian jumlah benih dan varietas terhadap beberapa karakter yang diamati. Terdapat keragaman yang nyata antar varietas yang diuji pada semua karakter.

Kata kunci: interaksi genetik lingkungan, jumlah populasi, kompetisi, produktivitas
Isolation of endophytic bacteria and fungi from soursop (Annona muricata L.) and bioactivity test as antimicrobial against Eschericia coli, Staphylococcus epidermidis, and Candida albicans
Authors: Aisyah Nurul , Zulkifli Lalu , Rasmi Dewa Ayu Citra
Published: March 2023

This study aimed to test the antimicrobial activity of endophytic bacteria and fungi isolates of soursop (Annona muricata L.) in inhibiting the growth of E.coli, S. epidermidis, and C. albicans. The stages of the research were the isolation of endophytic bacteria, antimicrobial assay, and characterization of potential endophytic bacteria and fungi. Endophytic microbial was isolated from leaves, bark, and root of soursop taken from Praya, Central Lombok. The agar diffusion method was used in the antimicrobial activity assay. Characterization was carried out on endophytic microbes with antimicrobial activity based on colony morphology, Gram staining, and biochemical tests. The antimicrobial activity test results showed that none of the endophytic bacteria and fungi isolates had intense activity inhibiting the test microbes' growth. Isolates with code DN3, DNX, and AKRX had medium activity against E. coli, isolates with code AKR1 had medium activity against S. epidermidis, and isolates with code DN2 AKRX had medium activity against C.albicans. The research results showed that the endophytic bacteria from soursop plants could inhibit the growth of test microbes in the weak to moderate.
Validity of powerpoint-ispring learning media on carbohydrate materials in high school
Authors: Lestari Mila , Guspatni Guspatni
Published: March 2023

Carbohydrate material is a theoretical chemical that connects every concept to make it seem abstract. It resulted in students needing help understanding the material. Learning media can help students understand the material, which can display animations, pictures, and videos. One learning media that can display this is the PowerPoint-iSpring learning media. This study aimed to determine the validity value of PowerPoint-iSpring learning media on carbohydrates for class XII high school students. This research is educational design research using the Plomp model. The subjects of this study were three chemistry lecturers at the Chemistry Education Study Program, Faculty of Mathematics and Natural Sciences, Padang State University and two high school chemistry teachers, and class XII students at SMAN 7 Padang. The instruments used were teacher interview sheets, student questionnaires, and validity test questionnaires. The type of data is primary data which was analyzed using Aiken's V formula. The results of this study obtained a content validity test of 0.85, construct validity of 0.81, and media validity of 0.81. In conclusion, the learning media developed could be categorized as valid.
Development of android-based learning media applications on mole concept topics for high school students
Authors: Depiyahani Istiva , Azra Fajriah
Published: March 2023

This study aims to develop a product in the form of an Android-based learning media application based on the mole concept material for class X SMA/MA that is valid and practical. The study uses the Plomp development research model, which consists of three steps: preliminary research, prototyping phase, and assessment phase. This research is limited to the prototyping phase for the practicality stage of the small group evaluation. Three chemistry lecturers carried out the product validity test at the Faculty of Mathematics and Natural Sciences, Padang State University, two Al-istiqamah High School chemistry teachers as material experts, and two lecturers of informatics engineering at Padang State University as media experts. Fifteen students and two chemistry teachers carried out the practicality test. The validity data analysis technique uses Aiken's V index. The validity test results showed that the Android-based learning media application developed belongs to the valid category with an average V value of 0.86 for material experts and an average V value of 0.93 for media experts. The practicality data analysis technique uses a percentage formula. The results of the practicality test in small groups are classified as "very practical," with a practicality percentage value of 90% for students' practicality and a practicality percentage value of 92% for teachers' practicality. Based on the results of the validation and practicality tests, it was found that applying android-based learning media to the mole concept material was valid and practical.
Prospective Effect of Pruritus Intensity on the Quality of Life of Neurodermatitis Patients at the NTB Provincial Hospital
Authors: Wedayani Anak Agung Ayu Niti , Hidajat Dedianto
Published: March 2023

Neurodermatitis is a skin condition that is very itchy and chronic. Its characteristics are characterized by the presence of one or more plaques that experience thickening of the skin. One characteristic of the skin surface of patients with neurodermatitis is tree bark, which is caused by repeated rubbing or scratching responses. The aim of this study was to prospectively determine the effect of pruritus intensity on the quality of life of neurodermatitis patients in Mataram City in August - September 2022. This study was a cross-sectional study to determine the effect of pruritus intensity on the quality of life of neurodermatitis patients in the period August - September 2022. Data on psoriasis patients obtained from the Provincial Hospital of West Nusa Tenggara. Pruritus intensity was measured by VAS and 5D. Quality of life was assessed using the DLQI. There is a significant correlation between the intensity of pruritus and the quality of life of neurodermatitis patients as seen from the value of P=0.000<0.05. Based on the intensity of pruritus, the severity of VAS was obtained in the severe category, namely 36 respondents (50.0%) and 5D in the moderate category, namely 42 respondents (58.3%), and the quality of life was moderately affected by 31 respondents (43.1%). Based on the results of the study, it was found that there was a relationship between the intensity of pruritus and the quality of life of neurodermatitis patients in the city of Mataram. This statement is in accordance with the results of the data that the majority of neurodermatitis patients with moderate-severe pruritus intensity have a quality that has a moderate effect on the patient's life
Analisis Daya Dukung Lahan Pertanian di Desa Penyangga Kawasan Ekonomi Khusus Mandalika - Kabupaten Lombok Tengah
Authors: Ayu Candra , Wuryantoro Wuryantoro , Wahoni Nurtaji , Ibrahim Ibrahim , Nurminda Dewi Mandalika Eka
Published: March 2023

The Mandalika Special Economic Zone in Central Lombok Regency plays a role in accelerating the distribution of national economic development in the region and strengthening the economy of the surrounding village communities. This study aims to analyze the carrying capacity of food crop farming land to farmer households in the buffer village of the Mandalika Special Economic Zone. The research method is descriptive and data collection using survey techniques. The research location is in the food crop center supporting villages (Sengkol, Rembitan and Sukadana villages) and the respondents are 45 farmers. (criteria for poverty in Sajogyo and the World Bank) and technical support using the Carrying Capacity Ratio formula. The results showed that the economic carrying capacity equivalent to rice was 312.52 kg/capita/year or US$ 0.55/capita/day and the welfare of farmers was classified as poor. The contribution of economic carrying capacity to the ability to fulfill staple food of farmer households is 65.11%. The carrying capacity of the land is technically high (CCR=1.99) so that the land is still able to: support the life of the population and receive additional population, as well as the development of food crop agriculture which is expansive and explorative in nature. Each farming household can have a planting area that is 1.2 ha larger than the average land ownership. Farming households can own a planting area of ​​1.2 ha larger than their average land ownership. In order for the carrying capacity of food crop farming land to prosper farmers, it is necessary to develop expansive and exploratory land, especially in the dry season and limit the conversion of agricultural land to food crops due to population growth in the buffer villages of KEK Mandalika - NTB.
A case of hepatic intraductal papillary neoplasm of the bile duct
Authors: Dorsaf Beltaifa , Sana Ben Slama , Sofiene Guebsi , Aziz Atallah , Nafaa Arfa , Ahlem Lahmar , Dhouha Bacha
Published: March 2023

Introduction: Intraductal Papillary Neoplasm of the Bile ducts (IPNB) is a rare entity characterized by exophytic growth of the bile ducts. Case presentation: In this report, we present a 57-year-old male with no prior medical history consulted for upper right abdominal pain, jaundice and pruritus. Abdominal Ultrasound (US) and magnetic resonance imaging/Bili-magnetic resonance were performed. They revealed that the circumferential parietal thickening of the common hepatic duct had extended approximately 4 cm with moderate dilatation of the left intrahepatic bile ducts. Computed tomography showed no evidence of distant metastasis. Biopsy revealed a high-grade intraductal papillary neoplasm. After 40 days, the patient had left hepatectomy with resection of the main bile duct and the gallbladder. Macroscopic examination of the surgical specimen showed a dilatation duct at the hilum with thickening of their walls. The histopathology report revealed multiple intra-hepatic papillary neoplasms with high-grade dysplasia with an invasive carcinoma component in the left hepatic duct without extending to the biliary wall, classified as pT1N0. Conclusion: This premalignant lesion has the potential to transform into invasive carcinoma if not properly diagnosed. Our case illustrates how early identification can lead to potential surgical resection.
Promotion of CO2 assimilation by Stopping of NOx, NP elimination are easy method to stop global warming and to growth
Authors: Shoichiro Ozaki
Published: March 2023

Global warming is caused by the retardation of CO2 assimilation by the elimination of NOx and NP in seven developed countries. Global warming can be protected, if enough amounts of nutrients containing nitrogen and phosphorous are supplied. Most easily available substances containing nitrogen and phosphorous are NOx and NP in waste water. But developed contrails are eliminating NOx by put in ammonia in the exit gas. and eliminating nitrogen and phosphorus in waste water by activated sludge process. CO2 assimilation is retarded and plankton and plant growth are retarded. If developed countries stop the addition of ammonia to the exit gas and close waste water clean center, CO2 assimilation is activated and CO2 does not increase and global warming will stop. In addition, production of grain and fish will increase and GDP, national wealth and population will increase. The goal “CO2 increase zero and growth” described in Paris Agreement could be accomplished sooner than 2050. Promotion of CO2 assimilation is essential for protection of global warming and for growth.
The Meaning of Home after Internal Migration for a Local-Based Community in Jakarta
Authors: Harahap Aris Masruri
Published: March 2023

In the context of urbanization in Indonesia, home for migrants is often associated with a place where they will return after leaving. This idea becomes even clearer on Lebaran Day. At that time, many of those who left their homes will do their biggest effort to come home and meet their loved ones at home. It is not to mention people from Lampung who join a local-based community called Komunitas Anak Lampung Selatan (Community of People from South Lampung) or KALS. These people left their hometown for Jakarta in the spirit of accumulating economic capital. This essay discusses the meaning of home for migrants by using KALS as a study case in the context of urbanization in Indonesia. As the analysis shows, the home for KALS is not unified as it involves different places. Since KALS came to Jakarta to gamble their fate, the successful or unsuccessful effort in economic capital accumulation in Jakarta also plays an important role in the meaning construction of homes for KALS. Those who are satisfied with accumulating economic capital tend to see Jakarta as their current and future home. At the same time, they see Lampung as a home to which they will return on special occasions like Lebaran Day which means it is only temporary. However, those who are not satisfied with accumulating the capital tend to see Lampung as a home where they will return permanently in the future and see Jakarta as merely a temporary home.
The Idea of The Health Omnibus Law as a National Legal Policy in an Effort to Increase Public Health Degrees in Indonesia
Authors: Bagiastra I Nyoman
Published: March 2023

This study aims to examine the ontological aspects of health promotion in an effort to improve public health status and to analyze the health sector in the General Agreement on Trade in Services. This research also aims to offer the idea of omnibus law health as a national legal policy in an effort to improve public health status in Indonesia. This article uses normative legal research methods using statutory approaches, conceptual approaches, and analytical approaches. The study indicates that the idea of an omnibus law on health as a national legal policy in an effort to improve public health status in Indonesia is a challenge as well as an opportunity. Considering that the health service sector has an important contribution to the sustainable development goals presented by the United Nations, that is, one of the goals of sustainable development is for a healthy and prosperous life. Therefore, it is necessary to revise and harmonize regulations both nationally and internationally which are based on Pancasila values to ensure that the mission is realized to improve public health in a comprehensive manner that is equitable, fair, and affordable and has legal certainty.
Problematics of Circular Letter as Follow-up to The Constitutional Court Decision
Authors: Irwansyah Irwansyah
Published: March 2023

The Constitutional Court’s decision is final and binding. It becomes effective as soon as it is pronounced in open. In practice, however, the Constitutional Court’s decision is followed by a variety of legal products, including laws, government regulations, and presidential regulations, and some even use circular letters. The method used in this paper is normative legal research. The purpose of this study is to analyze the circular letter as a follow-up to the Constitutional Court’s decision. The use of generalized letters in response to a Constitutional Court decision is deemed inappropriate. Because the dissemination is not a legal regulation, it is not necessary to follow the Constitutional Court’s decision when considering the law. In an ideal world, the Constitutional Court’s decision is followed by legislation.
Kedudukan Izin Lingkungan Dalam Sistem Perizinan Di Indonesia
Authors: ' Helmi
Published: March 2023

As an instrument of environmental resource management, environmental permits has an important position. Lay No. 32 of 2009 on the Protection and Environmental Management (UU-PPLH) permits the integration of various environmental permits before splitting. But the problems faced, it turns out, the law it self is still not firmly UU-PPLH provide the scope and type environmental permit it self. Status of environmental permits for a business license or activities appear on the scope and legal relations of both, which is an instrument of obtaining environmental permits and business licenses or implement environmental management activities.
KEJAHATAN KORUPSI BIDANG PERTANIAN : PELANGGARAN HAK ASASI MASYARAKAT DALAM MEWUJUDKAN KESEJAHTERAAN MASYARAKAT YANG BERKEADILAN SOSIAL
Authors: Lestariningsih Sri
Published: March 2023

Food is a major necessity forhuman life in the world, evenfrom a very close association withfood clashing civilizations. But thefacts show that tngkat corruptionin ministries / agencies in the fieldof agriculture in central Indonesiawas ranked first based on datacorruption by authority. Based onthe specificity of the nature of thecrimeofcorruption,theenforcement of this crime requiresspecific ways as well. Lawenforcementforcrimesofcorruption needs to be donesimultaneouslyandsynergy,between the law enforcementdilaterapkankonsitenwithgovernment strategic policies inagriculture or food, so the risk orimpact of corruption crimes thatoccurred in the field of food willnot be just too bad for society.
PERBANDINGAN HUKUM PENYELESAIAN SENGKETA SECARA MEDIASI DI PENGADILAN DAN DI LUAR PENGADILAN DI INDONESIA
Authors: Lestari Rika
Published: March 2023

Dispute resolution as mediationhas been known since the first inIndonesia because of the customssystem in resolving a case alwaysuphold discussion and consensusthrough traditional forums ofeach region in Indonesia. As itgrows by time, this is enforced inthe court (Court ConnectedMediation) as form of justice law.However, mediation process incourt has to be enforced throughthe civil dispute resolution. Ifmediation as set forth in SupremeCourt Rule No. 1 of 2008, ifmediation is not implemented, thejudgment will be omitted for lawpurpose.
Case report: drug-induced melanosis in 21-year-old woman treated by gingival depigmentation
Authors: Sabirin Indah Puti Rahmayani , Fakhira Zalfa Puspa
Published: March 2023

Background: Oral pigmentation can be caused by long-term consumption, smoking or physiology. Drug induced melanosis is one of the oral pigmentation caused by long-term medication use. Changes in the color of the oral mucosa can be and provide local or systemic diagnostics, it is necessary to carry out a significant examination and findings from the patient properly.Case Report: The method used is a case report with primary data analysis obtained through anamnesis, as well as intra-oral examinationConclusion: The diagnosis of patients with drug induced melanosis with clinical features found in the gingiva of the maxillary and mandibular anterior teeth, this is because the patient has a history of bronchitis and has been taking antibiotics for a long time. To overcome this pigmentation, the patient underwent OHI and gingival depigmentation treatment and the results showed reduced gingival pigmentation after 1 month postoperatively.
Sülfürlü bakır-molibden konsantresinin asidofilik bakteriler ile seçimli biyoflotasyonu
Authors: Çiftçi Hasan , Avcı Suzan
Published: March 2023

Bu çalışmada, sülfürlü bakır-molibden cevherinden (%0,458 Cu, %0,042 Mo) elde edilen toplu Cu-Mo konsantresinin (%12,02 Cu, %1,37 Mo) biyoflotasyon yöntemiyle zenginleştirme olanakları araştırılmıştır. Pülp pH’sı, bakteri türü ve bakteriyel kıvamlama süresi değişkenlerinin Cu-Mo konsantresinden seçimli olarak kalkopirit ve molibdenit konsantrelerin kazanımına etkileri incelenmiştir. Toplu konsantreden kalkopiritin bastırılması amacıyla asidofilik Acidithiobacillus ferrooxidans ve Acidithiobacillus thiooxidans türü bakteriler kullanılmıştır. Düşük pH’da (2-2.5) yapılan biyoflotasyon deneylerinde seçimliliğin olmadığı görülmüştür. At. ferrooxidans ile pH 5-6 aralığında yapılan biyoflotasyon sonucunda, %3,2 Mo içeren %88,2 verimle bir molibdenit konsantresi ve %15,65 Cu içeren %80,6 verimle bir kalkopirit konsantresi üretilmiştir. At. ferrooxidans türü bakterinin, At. thiooxidans’a göre kalkopiriti daha etkin şekilde bastırdığı belirlenmiştir.
The impact of cholecalciferol on cognitive performance in patients with hypothyroidism and autoimmune thyroiditis
Authors: Kamyshna I. I.
Published: March 2023

Hashimoto’s thyroiditis is a chronic autoimmune thyroiditis characterized by lymphocytic infiltration that may result in the gradual loss of thyroid tissue. According to a study, even with normal thyroid function, autoimmune thyroiditis can cause neuroinflammation, leading to emotional changes and mental disorders. Although the mechanism is unclear, some research indicates that vitamin D has a beneficial effect on autoimmune thyroid diseases. The relationship between serum vitamin D levels and cognitive impairment in patients with autoimmune thyroiditis has been established in clinical studies.
Objective — to investigate the impact of cholecalciferol on cognitive function in patients with hypothyroidism and autoimmune thyroiditis in the Western Ukrainian population.
Materials and methods. The study involved 56 patients diagnosed with hypothyroidism resulting from autoimmune thyroiditis. These patients were divided into two groups. Group 1 (n=28) received cholecalciferol at a dose of 4000 IU/day (28.000 IU/week) and L‑thyroxine (88.39±12.70 mg/day), while Group 2 (n=28) received only L‑thyroxine (87.50±12.73 mg/ day). Assessments were conducted at the start and end of a 12‑week treatment period, and cognitive function was measured using the Mini‑Mental State Examination. The results showed a decline in cognitive function.
Results. Following the treatment course, patients demonstrated an improvement in cognitive function. In Group 1, where patients were treated with cholecalciferol and L‑thyroxine, the proportion of patients with moderate (pre‑dementia) cognitive impairment decreased from 50% to 21.4%. However, there were no significant changes observed in the group that received only L‑thyroxine. Normalization of cognitive function as determined by the MMCE test increased from 28.6% to 78.6% in Group 1, and from 21.4% to 50% in Group 2 patients.
Conclusions. Based on our findings, vitamin D supplements should be given to patients diagnosed with autoimmune thyroiditis and hypothyroidism in order to enhance cognitive function.
Modern approaches to the management of patients with obesity (according to the materials of the Consensus of the American Gastroenterological Association in 2022)
Authors: Tkach S. M. , Pankiv V. I. , Yuzvenko T. Y.
Published: March 2023

Over the past few decades, the prevalence of obesity has increased dramatically worldwide. Obesity‑related complications such as cardiovascular disease, stroke, type 2 diabetes mellitus, nonalcoholic steatohepatitis, obstructive sleep apnea, osteoarthritis, and certain cancers (eg, colorectal cancer) have also increased, contributing to the high incidence and mortality. Lifestyle modification is the mainstay of long‑term treatment for obesity, but it has limited effectiveness and durability for most people. Pharmacotherapies developed and approved for the long‑term management of obesity are more effective in achieving weight loss, although the daily use of anti‑obesity medications is limited for many reasons. Prioritizing the development of clinical guidelines to inform the use of pharmacologic therapy for the long‑term treatment of obesity in adults, the American Gastroenterological Association published its consensus in 2022 that addresses the important desired (benefits) and undesired (harms) pharmacotherapy outcomes for patients. Outcomes of critical decision‑making included percent of total body weight loss (TBWL), proportion of patients achieving >5%, >10%, and >15% TBWL, discontinuations due to side effects, and serious adverse events. The mean difference of 3% of TBWL between adjunctive pharmacotherapy and lifestyle modification alone, or an absolute 5% of TBWL above the baseline, was considered as a minimal clinically important difference in the effectiveness of pharmacotherapy in the treatment of obesity that corresponded to important benefits for patients. The strength of evidence for all outcomes was assessed using the GRADE system, in which evidence from randomized clinical trials was interpreted as high‑certainty, and confidence in the evidence conveyed confidence in the effect estimates. For each outcome, the evidence was divided into 4 categories (high, moderate, low or very low). According to the GRADE approach, recommendations were marked as «strong» when the phrase «we recommend» was used, or «conditional» when the phrase «we suggest» was used. The guideline panel made 9 recommendations and strongly recommended the use of pharmacotherapy in addition to lifestyle intervention in adults with overweight and obesity who have an inadequate response to the lifestyle interventions. Four drugs have been approved by FDA for long‑term use in obesity: liraglutide 3.0 mg/day, semaglutide 2.4 mg/week, phentermine‑topiramate ER, and naltrexone‑bupropion ER. They are considered to have moderate to significant effects on weight loss and little or no harm, so these drugs have a positive balance in favor of their long‑term use. Unfortunately, the last three drugs are not registered in Ukraine.
The role of DAP IV activity testing in the cytological examination of tumors of the «gray zone» TBSRTC IV in the prediction of papillary thyroid cancer and metastases
Authors: Tovkai O. A. , Palamarchuk V. O. , Kozachuk Y. S. , Belemets N. I. , Kuts V. V.
Published: March 2023

One of the most effective methods of thyroid nodules diagnosis is the fine‑needle aspiration puncture biopsy (FNAPB), allowing evaluation of the cytological characteristics of thyroid tumors. To improve the diagnostic efficiency of cytological investigations, additional methods can be implemented, including cytochemical determination of dipeptidyl aminopeptidase (DAP IV).
Objective — to analyze and establish the DAP IV activity thresholds, at which the probability of detecting papillary thyroid cancer (PTC) and its metastases in lymph nodes is clinically significant in patients with cytological conclusion of the TBSRTC IV category.
Materials and methods. For the first time in Ukraine, an analysis was made of the possibility of using DAP IV to predict papillary cancer and its metastases in cases of tumors with TBSRTC IV using ROC analysis to determine the threshold values of DAP IV activity, defining the clinically significant probability of metastases.
Results. It has been established that 6 is the cut‑off DAP IV value for diagnosis of papillary thyroid cancer, and 8 is the cut‑off point for the presence of its metastatic deposits. Thus, in case of DAP IV activity values between 6 and 8, the probability of papillary thyroid cancer diagnosis and its metastases significantly increases. The prognostic value of a positive result, i.e. obtaining a malignant diagnosis with DAP IV 6 activity, is 85.1%, which can be interpreted as high. With increasing DAP IV activity in patients with TBSRTC IV category, the probability of the reveal of papillary thyroid cancer metastases increases (threshold value of activity for DAP IV metastases 8 with counter sensitivity 0.267).
Conclusions. The obtained results allow a practitioner to choose treatment options: with values of DAP IV <6, the alternative therapies or active monitoring can be used, and with DAP IV <8, the need for preventive dissection may not be advisory.
VALORIZATION OF ROASTED HAZELNUT CUTICLES SUPPORTED BY LABORATORY TECHNIQUES
Authors: Miccio Michele , Fragranza Michela , Zainutdinova Aisylu , Tauleigne Blandine , Brachi Paola , Casa Marcello , Ferrari Giovanna , Kostryukova Natalya
Published: March 2023

this paper reports the experimental results of an on-going project running at lab-scale and aimed at the valorization of roasted hazelnut cuticles through both chemical (i.e., solvent extraction) and thermochemical treatment (i.e., torrefaction) routes. In particular, the potential of using water as a green solvent for the extraction of bioactive compounds (i.e., substances of chemical-food-pharmaceutical interest, such as the polyphenols) contained in residues originated by industrial processing of hazelnuts has been investigated, applying the conventional laboratory Soxhlet extraction procedure. A subsequent valorization stage has been explored for the spent post-extraction residues versus the “as collected” ones; they lend themselves to become “renewable” solid fuels thanks to torrefaction, which is a “mild” thermochemical conversion process. The obtained results are first presented in terms of theoretical yields of the bioactive compounds of interest with respect to the original mass of hazelnut residue; in addition, the findings on torrefaction are discussed in terms of performance indexes with respect to the torrefied fuel and quantitatively expressed as correlations as a function of temperature.
WASTE CHARACTERIZATION IN THE URBAN CANAL NETWORK OF PADOVA (ITALY) TO MITIGATE DOWNSTREAM MARINE PLASTIC POLLUTION
Authors: Poli Valentina , Lavagnolo Maria Cristina , Barausse Alberto , Benetello Elena , Palmeri Luca
Published: March 2023

Concern about plastic pollution in coastal wetlands, seas and oceans has risen dramatically in recent years. Most of the waste found in the environment has a land-based origin and it is transported toward coastal-marine ecosystems through rivers and canals. Thus, waste collection in watercourses flowing through urban areas has a great potential to mitigate plastic pollution in local and coastal water bodies. In this paper, authors describe the results of three waste collection campaigns performed during 2021 (early summer, late summer and autumn) in three representative points of the channel network of the historical center of the city of Padova, Italy, where restoration efforts of the urban stream ecosystems are ongoing. The collected waste was analyzed both in terms of size and material type. A total of 418 kg of waste was collected: the prevailing fraction was the coarse one (59% of the material intercepted by a 100 mm side mesh sieve), and plastic represented the most abundant waste category (47% by weight). The total amount of litter produced in one year from the channel network of the city of Padova was estimated, with litter amounts on the canal banks found to be much higher than or at least comparable to those in water, a result which highlights the importance of planning waste collection together with riparian vegetation management to reduce plastic pollution. These findings provide a baseline for assessing the possibility to valorize the waste collected from the waterways of the city with processes other than landfilling and incineration
IN SEARCH OF THE MATERIAL COMPOSITION OF REFUSE-DERIVED FUELS BY MEANS OF DATA RECONCILIATION AND GRAPHICAL REPRESENTATION
Authors: SchwarzbaCk Therese , Hahn Manuel , Spacek Stefan , Fellner Johann
Published: March 2023

Differenciating between material fractions in refuse-derived fuels (RDF) is relevant to determining the climate relevance of RDF (fractions of biomass and fossil matter). This differentiation is associated with analytical challenges. A method was applied using balance equations, which contain the elemental composition (C, H, N, S, O) of the RDF and the sought for material fractions. For the first time this so-called adapted Balance Method (aBM) was applied to oil-contaminated RDF with the aim of not only distinguishing between biomass and fossil matter but between fossil matter from plastics and from oil-contamination as well. Thus, the balance equations and the following data reconciliation was adapted. It is shown that the balance method is based on mathematics that provides valuable insight far beyond the basic types of calculation since the calculation takes place in higher dimensions. It is also shown that the operation of the algorithm can be represented graphically in the lower third dimension. The mass of oil contamination as well as the mass of biogenic and fossil matter could be determined for the RDF considered. Problems concerning relatively high uncertainties still need to be solved due to the similar elemental composition of plastics and oil. However, it is shown that the aBM is capable of distinguishing between more than two material fractions in RDF, which the other available methods cannot and which can be relevant for greenhouse gas reporting but also for process control purposes.