bluuebunny/crossref_metadata_2025 huggingface dataset:
Short-Term Outcome of Laparoscopic Intraperitoneal Hernioplasty of Incisional Hernia in Khulna Medical College Hospital
Authors: Rahman Md. Mustafizur , Das Arindam , Bhuiyan Md. Masud Rana , Haque Sayidul , Saha Haridas , Arifuzzaman Md.
Published: September 2023

Background: Herniorrhaphies that apply a large prosthetic mesh appear to have a lower failure rate, but extensive dissection of soft tissue contributes to an increased incidence of wound infections and wound-related complications. The method of laparoscopic incisional hernia repair was developed in the early 1990s. This technique is based on the same physical and surgical principles as the open underlay procedure. Therefore, this operation has increased in popularity promising shorter hospital stay, improved outcome and fewer complications than traditional open procedures. The aim of the study was to see the short-term outcome of laparoscopic intraperitoneal hernioplasty of incisional hernia in Khulna medical college hospital. Material & Methods: This study was prospective single-cantered observational study carried out at the department of surgery; Khulna Medical College Hospital included 30 patients of incisional hernia those who underwent laparoscopic intraperitoneal on lay mesh (IPOM) technique using polypropylene mesh and the mesh was fixed with Tacker. The duration of the period from January, 2013 to June, 2013. Data was collected by researcher himself with face-to-face interview using a prepared structured questionnaires & checklist and analyzed on SPSS 22. Results: The study was done on 30 patients among which 13 (43.3%) were male and 17 (56.6%) were female patients. Among them the maximum male and female came from 41-50 years age group. Among the 30 patients 16 belonged vertical incisional hernia, whereas 13 patients belonged transverse incisional hernia and the size of the defect of hernia in 27 were medium (defect is 5-10cm) and in 3 were small (defect is <5cm). 21 patients underwent emergency surgery, whereas 9 patients underwent elective surgery for different diseases previously. Every patient in this study group had some predisposing factors to appear incisional hernia. Of them, 16 (53.33%) patients were suffering from Diabetes mellitus, 6 (20%) patients were suffering from chronic cough 2 (6%) patients from chronic retention of urine, 4(13.33%) from chronic constipation and 8 (26.67%) patients from immunocompromised condition due to diseases or drugs taken by them. In case of preoperative complication, only 1 (3.3%) patient each experienced omental haemorrhage, visceral haemorrhage, bowel injury and open conversion whereas 2 (6.6%) patients featured port site bleeding. As postoperative complication, the study shows that 4 (13.3%) patients developed paralytic ileus in followed by port site infection in 3(10%) patients. Conclusion: Laparoscopic hernioplasty is safe and convenient repair in short-term in our clinical setup. But to reach a precise conclusion a long-term case control study with conventional mesh hernioplasty in multiple centres should be done.
Clinical Profile of Patients with Carcinoma Gall Bladder a North Indian Perspective
Authors: Rampal Kapil , Kaur Harkanwalpreet , Sandhu Parampreet Singh , Snehi Nitesh , Kumar Ankush , Sharma Meghna , Khichy Sudhir
Published: September 2023

Background: Gallbladder cancer (GBC), although rare, is the most common of biliary tract malignancy. It has been thought to be fatal disease with an extremely poor prognosis. Gallbladder cancer is often discovered incidentally after cholecystectomy performed for gall stone disease. Material & Methods: It is an retrospective observational study conducted in our surgical unit of Guru Gobind Singh Medical College and Hospital, Faridkot, India. Case records of 106 patients, from June 2017 to December 2022 were analyzed. Results: A total of 56% cases were in more than 60 years of age group and the mean age recorded was 58 years. 54.7% cases were females and 62.3% cases had a rural background. 59.4% of the cases were from lower socio-economic strata. A body mass index of more than 30 was recorded in 72.7% cases. 62.3% patients gave history of tobacco abuse. 39.6% cases were natives of Punjab and 37.8% cases were migrants from the Gangetic belt (Uttar Pradesh and Bihar). Pain abdomen was the most common presenting symptom found in 67.9% cases. 54.7% cases presented with abdominal mass. Majority of the patients (67.9%) reported in Stage 4 of the disease. Fundus involvement was seen in 45.3% cases. 94.3% cases had associated gall stones with 64.2% cases having multiple stones. Conclusion: We studied the clinical profile of the patients with gall bladder carcinoma and found its high incidence in the fifth decade of life and its association with female sex, low socio economic status, obesity, local and Gangetic belt ethinicity, gall stones and a late stage at presesentation.
Study of Clinico- Epidemiological Profile of Patients with Gallbladder Perforation
Authors: Rampal Kapil , Singh Parampreet , Harkanwalpreet Harkanwalpreet , Singh Harinder , Sharma Meghna
Published: September 2023

Background: Gallbladder perforation (GBP) is rare but a potentially fatal disease; its presentation can vary and hence is difficult to diagnose early. It is usually a complication of acute cholecystitis with or without gallstones. Most perforations are subacute, producing a pericholecystic collection. Acute free perforation with biliary peritonitis and chronic perforation with an internal biliary fistula are rare. The fundus of the gallbladder is the most common site of perforation because of its poor blood supply. Material & Methods: This retrospective observational study included all cases of gallbladder perforation that presented to general surgery ward from January 2019 to January 2022. Cases of traumatic gallbladder perforation and gangrenous gall bladder were excluded. The patients were assessed for epidemiological and clinical parameters like age, gender, socio economic status, presenting complaints, history of substance abuse, co- morbidity, hemoglobin, total leucocyte count, renal function tests, liver function tests, history of fever, fever on presentation, pulse, blood pressure and respiratory rate on presentation, type and site of perforation, method of management, diagnostic procedures(ultrasound and contrast CT abdomen findings), duration of hospital stay, and post-operative complications if any were evaluated. Results: This study included 14 patients ( 4 males and 10 females). The mean age of patients was 63.7 years. Gallbladder perforation was most common in the 5th and 6th decade of life. Two Patients had type l perforation and 12 patients had type ll perforation(Neimer’s classification) . Cases were diagnosed on the basis of contrast enhanced CT scan. Patients were managed with carbapenems, intravenous fluids and analgesics . 11(79%) patients were managed conservatively. One patient presented with impending rupture of anterior abdominal wall abscess that was communicating with pericholecystic abscess. Patients on conservative management were managed empirically with Carbapenem antibiotics and recovered well. Two patients underwent cholecystostomy. The mean hospital stay was 11.5 days for conservatively managed group and 18 days for patients who underwent upfront surgery. There was no reported mortality. All patients underwent interval open cholecystectomy after 06 weeks.Mean post operative hospital stay was 4 days in these patients. Each patient was followed up for 06 months in outpatient department and through telecommunication. Conclusion: Gallbladder perforation represents a special diagnostic and surgical challenge. Careful selection and management of patients with broad spectrum antibiotics can help us manage patients conservatively.
Use of the WINROP Screening Algorithm for the Prediction of Retinopathy of Prematurity (ROP): A Hospital-Based Study
Authors: Barkat Shahreen , Hossain Mohammad Monir , Shirin Mahfuza , Shetu Tanima Mahmud , Mahmud Mohammad Al
Published: September 2023

Background: Retinopathy of prematurity (ROP) may be the blinding disease that affects the retina of neonates. WINROP utilizes the rate of postnatal weight increase as a replication of IGF-1 or uses weight increase and IGF-1 levels together as highly analytical markers for those infants at increased risk for the development of proliferative ROP. So this study was undertaken to find out the sensitivity and specificity of this algorithm concerning international screening guidelines to predict retinopathy of prematurity. Material & Methods: A prospective cross-sectional study was carried out in the Department of Neonatology, Bangladesh Shishu Hospital & Institute from January 2017 to December 2018. A total of 50 neonates (N=50) with proper documentation following the inclusion and exclusion criteria were confirmed as the study population. Informed written consent was obtained from all the parents or guardians after they were thoroughly briefed about the nature and purpose of the study. Data were processed and analyzed using statistical package for social sciences (SPSS-22 version) software (SPSS Inc., Chicago, IL, USA). The ethical review board of the Bangladesh Institute of Child Health approved the protocol of this study. Results: The mean gestational age was 29±1.17 weeks in ROP-positive cases and 31.79±0.51 weeks in ROP-negative cases. The mean weight was 1121.9±94.34 grams in ROP-positive cases and 1302.7±139.72 grams in ROP-negative cases. It was observed that the majority 92.3% of the ROP positive cases had weight gain ≤10gm/kg/day for 4 weeks but 87.5% of the ROP negative cases had weight gain >10gm/kg/day. The validity test of WINROP for the prediction of retinopathy has a sensitivity of 92.3%, specificity of 87.5%, and positive predictive value of 88.9% and negative predictive value of 91.3%. Low-grade ROP – In zone II or III and stage 1. High-grade ROP – In zone I and stage 2 or more and plus disease. Conclusion: Retinopathy of prematurity (ROP) is a severe eye infection that can affect premature neonates. In this study, WINROP predicted 92.3% sensitivity and 88.9% positive predictive value in comparison to the gold standard screening method for detecting ROP within 2 weeks of birth.
Pelos caminhos da loucura e da nudez: a performance do corpo transgressor no conto “Aí pelas três da tarde”, de Raduan Nassar.
Authors: Navarro Martins Maria Luiza , Franco Nobile Brandileone Ana Paula
Published: September 2023

Este estudo analisa o conto “Aí pelas três da tarde”, de Raduan Nassar, a fim de investigar a presença da performatividade no texto literário, dado o protagonismo do corpo que atua como signo narrativo. No conto, o discurso, dirigido a um narratário, é ferramenta de transgressão de interditos laborais, sociais e morais. Nesse contexto, o corpo inscreve-se não somente como objeto de representação, mas como elemento composicional, que conduz o discurso narrativo.
Livro ilustrado: da composição ao sentido
Authors: Munhoz Estella Maria Bortoncello , Ramos Flávia Brocchetto
Published: September 2023

A literatura infantil e juvenil é um objeto artístico e estético formado, no caso do livro ilustrado, pela interação de linguagens. Esta pesquisa investiga o livro ilustrado de natureza narrativa, tendo como enfoque a composição da visualidade. O objetivo é apontar elementos composicionais das ilustrações presentes nesse gênero e características dos paratextos. A pesquisa justifica-se pela relevância do livro ilustrado na formação literária e humana dos leitores e pela importância das imagens na construção de narrativas. Por meio de revisão bibliográfica e de análise qualitativa da dimensão visual de narrativas literárias, são analisados elementos como ponto, linha, contorno, forma, perspectiva, dimensão, cores, ritmo, design gráfico e paratextos. O estudo demonstra a relevância da imagem, muitas vezes tida como secundária, na geração de sentidos de enredos. Destaca-se ainda o papel fundamental do design gráfico, que propicia a união entre as instâncias verbal e visual e constrói a materialidade do livro.
A leitura literária e a posição de leitor em metapoemas contemporâneos
Authors: Grazioli Fabiano Tadeu
Published: September 2023

Observar a leitura, em especial, a literária, quando ela é motivo do poema e refletir sobre o enquadramento que ganham, na abordagem lírica, o leitor e sua atividade de atribuir sentido ao que lê. A partir desse entendimento, o estudo procura realizar um exercício de leitura de metapoemas de acordo com pressupostos teóricos do campo da leitura literária. Dessa forma, são apresentadas proposições teóricas de Graciela Montes (2020), Jeferson Tenório (2021), Roland Barthes (2012), Jan Tschichold (2007), María Teresa Andruetto (2012), entre outros, e, em seguida, colocados em diálogo com poemas de Marcelo Labes (2020), Armando Linguori Junior (2021) e Marion Cruz (2020). Da conclusão, podemos mencionar, em síntese, que os poemas se articulam em torno da ideia de que a leitura literária exige uma “posição de leitor”, expressão de Montes (2020) explorada no estudo e que encontra correspondência nas considerações de Tenório (2021) e Barthes (2012). Os poemas analisados assumem vozes líricas distintas, mas fazem coro a uma posição de leitor que se mantém coesa, no qual prevalece uma conjuntura da atividade de leitura cuja perspectiva desloca a atenção para o leitor. Tal encaminhamento favorece a busca do modo de produção do sentido do texto literário a partir de um sistema que concebe a leitura na perspectiva lúdica, associativa e dispersiva que lhe é característica, conforme propõe Barthes (2012).
Estéticas dissidentes e educação: potente e sensível
Authors: Alves Karina Feltes , Schenkel Júlia Duarte
Published: September 2023

Trata-se de uma resenha a partir do ebook "Estéticas dissidentes e educação, organizada por Mário de Faria Carvalho, Daniela Nery Brancchi e André Luiz dos Santos Paiva, publicada em 2022, em formato digital, pela editora Pimenta Cultural.
Sovereign portfolio composition and bank risk: the case of European banks.
Authors: Bahar Baziki Selva , Nieto María J. , Turk-Ariss Rima
Published: September 2023

We extend the literature on the sovereign-bank nexus by examining the composition effects of sovereign portfolios on banks’ risk profile, unlike previous studies which generally analyzed the determinants of banks’ sovereign portfolios or the size effects of these portfolios. We also differ from previous studies with respect to the measures of risk considered and by covering a sample period that goes well beyond the global financial crisis (2009-2018). Drawing on granular data from the European Banking Authority, we find that banks are riskier when their portfolio includes a higher proportion of securities issued by higher-risk sovereigns or when they are themselves domiciled in a country with high sovereign credit risk. Nevertheless, we do not find conclusive evidence that larger holdings of government securities of the country where the bank is incorporated increase bank risk ex-post. However, the risk profile is higher for banks that received government capital injections than for banks that did not receive capital support in the aftermath of the global financial crisis. Banks that received government capital injections are less risky when their portfolio includes a higher proportion of securities issued by higher-risk sovereigns. These results may indicate that regulatory arbitrage motives at these banks are particularly important.
The importance of functional analysis: a cautionary case of cerebellar ataxia
Authors: Jayadev Menon Poornima , Bogdanova-Mihaylova Petya , Green Andrew , Smith Kenneth , Yarram-Smith Laura , Taylor Malcolm , Byrd Philip , Dibra Harpreet , Walsh Richard A. , Murphy Sinead M.
Published: September 2023

Introduction. Cerebellar ataxias are a heterogeneous group of disorders with various cerebellar and extracerebellar manifestations. The underlying aetiology in early-onset, progressive, sporadic ataxia, is often autosomal recessive cerebellar ataxia (ARCA). The advent and rapid clinical integration of next-generation sequencing (NGS) has made it increasingly possible to provide a genetic diagnosis for patients with suspected ARCA. However, one of the greatest challenges of NGS is the interpretation and reclassification of variants of uncertain significance (VUS).
Case report. Ataxia telangiectasia was suspected due to progressive teenage-onset ataxia in a 42-year-old woman with a history of breast cancer, ovarian mass, and elevated alpha-fetoprotein and CA-125. ATM sequencing demonstrated a homozygous missense VUS. However, functional studies clarified that this VUS was not pathogenic, but there was reduction in senataxin. This enabled clarification that the diagnosis was ataxia with oculomotor apraxia type 2.
Conclusion. Our case highlights the importance of functional studies, where possible, to enable reclassification of VUSs.
DEVELOPMENT OF MUNICIPAL EMPLOYEES’ FLEXIBLE SKILLS AS THE CRITERIA OF EFFICIENCY AND QUALITY WORK
Authors: Хатукай С.А. , Бабалян Э.Б. , Адамчук А.А.
Published: September 2023

Данная статья анализирует важность развития гибких навыков у муниципальных служащих в качестве критериев эффективности и качества работы. Гибкие навыки включают способность к адаптации к изменяющимся условиям, толерантность к неопределенности, коммуникационные и лидерские навыки, а также умение работать в коллективе. Целью данной научной статьи является исследование и анализ развития гибких навыков у муниципальных служащих в контексте их влияния на эффективность и качество работы на примере муниципальных служащих администрации муниципального образования «Город Майкоп». В статье рассмотрены методы и подходы к развитию гибких навыков у муниципальных служащих, описаны программы обучения, тренинги и мероприятия, которые будут способствовать повышению гибкости и развитию соответствующих навыков.

The importance of developing flexible skills among municipal officials as the criteria of effectiveness and quality work is considered. The ability to adapt to changing conditions, tolerance for uncertainty, communication and leadership skills, as well as the ability to work in team are performed. The aim of the study is to analyze the development of flexible skills among municipal officials in the administration of the municipal entity "City of Maykop". Methods and approaches of developing municipal officials flexible skills are presented. Training programs, workshops, and events that can help to enhance flexibility and develop relevant skills are described.
The History of International Relations in the Legacy of the Soviet Historian Vladimir M. Khvostov (1905–1972)
Authors: Imamutdinova A. M.
Published: September 2023

In the article, based on a large number of archival documents, some of which were first put into scientific circulation, the research activities and problems of scientific research by V.M.Khvostov are considered. The author analyzed two main directions in the work of the scientist: the history of diplomacy and international relations; problems of general and national history (mainly the events of world wars). The contribution of V.M.Khvostov to the study of this issue is determined, his creative biography is considered as one of the models of the life and career of a scientist in the Soviet political and historiographic space.
Military Formations of the Central Asian Military District in Defensive Battles near Moscow
Authors: Aberkulov D. N.
Published: September 2023

The article examines the role and significance of the military formations of the Central Asian Military District that participated in the battles near Moscow during the Great Patriotic War. The novelty of the article lies in the fact that the author for the first time analyzed previously classified and therefore inaccessible archival documents and newly published materials about the heroism of the soldiers of the Central Asian Military District, who took their rightful place in the ranks of the defenders of Moscow. At the end of 1941, 21 cavalry and 16 rifle divisions, 25 rifle brigades were formed in the Central Asian Military District. The entry of the Soviet Union into World War II dramatically increased the potential of progressive forces opposing fascism, as a country with great military and economic potential, with peoples having heroic traditions, entered the war.
Japan’s Foreign Policy Priorities during the Prime Minister Yoshihide Suga Period: “Restoring Diplomacy and Security”
Authors: Letiaev V. A. , Magdeev R. R.
Published: September 2023

The article analyzes Japan’s foreign policy during the period of Yoshihide Suga’s activity as Prime Minister (2020-2021): the specifics of diplomacy and security activities, the common interests of Japan with other countries, the specifics of rapprochement and forms of interaction with different countries. The results of Japan’s foreign policy in Northeast Asia in the context of the COVID-19 pandemic, Japan’s military cooperation within the quadrilateral alliance “Quad” are presented.
Friedrich Ratzel’s Law of the Spatial Growth of States in the Situation of the New World Order Formation
Authors: Barakhvostov P. A.
Published: September 2023

In this paper, on the basis of an institutional approach, it is analyzed how fair the “law of expansion” of F. Ratzel is in the current situation of the formation of a new world order. It is shown that in modern conditions the instinct of self-preservation induces social systems not to territorial expansion due to an increase in the occupied geographical space, but to integration in various forms, which is based on a single normative approach to the mechanisms of the functioning of the union. In this sense, integration is a kind of expansion of the space occupied by society. Integration unions can increase, but up to a certain limit (saturation limit), determined not by the boundaries of geographical space, but by the possibility of developing a common position on the main issues of functioning, common norms and practices. As a rule, alliances are not absolutely symmetrical and include the “core” and the periphery of integration. The former include the most economically and politically strong states. At the same time, due to the asymmetry of the unions, the “core” institutions are transplanted to the periphery and there is a bidirectional institutional diffusion, which is due to the desire for institutional convergence, and this facilitates interaction within the union. Thus, “channels” for the institutional expansion of integrable societies are formed within the unions. Transplantation and diffusion of institutions are the mechanisms for the implementation of expansion in modern conditions. It is shown that when integrating social systems in order to mitigate possible institutional imbalances, the action of institutions that are complementary to the dominant ones in the institutional matrix is included: when integrating X-matrix countries - market ones, and vice versa.
New Trends and Prospects of Hydrogen Energy in the World and in Kazakhstan
Authors: Ibrayeva A. E.
Published: September 2023

The article explores the trends in the development of hydrogen energy both in the world in general and in Kazakhstan in particular. The author considers the growing interest in hydrogen energy in the context of the need to reduce greenhouse gas emissions and search for alternative energy sources. The article analyzes key international and national initiatives in the field of hydrogen energy, including the development of technologies for the production, storage and use of hydrogen. Particular attention is paid to the role of Kazakhstan in the development of hydrogen energy and its cooperation with other countries, especially with the EU and Japan, which has significant experience in this area. The author draws conclusions about the prospects for hydrogen energy.
Contractual Legal Framework for Military-Technical Cooperation between the Republic of Armenia and the Russian Federation
Authors: Manukyan Zh. S.
Published: September 2023

The article deals with the contractual legal foundations of military-technical cooperation between the Republic of Armenia and the Russian Federation. The features of the development of military-technical cooperation, events affecting the formation of its contractual legal framework within the framework of the Commonwealth of Independent States and the Collective Security Treaty Organization, the significance of cooperation are shown.
Aedes Mosquito Population density of Dengue Fever Vectors in The Area of Pineleng Minahasa
Authors: Manuahe Carolin , Mokosuli Yermia Semuel , Tumbel Ferny Margo
Published: September 2023

Aedes mosquitoes have the behavior of sucking blood repeatedly (multiple bites) in one gonotrophic cycle, these mosquitoes are also very effective at transmitting the virus to humans (WHO 2004). Kawada et al. (2007) reported that the foraging activity of A. albopictus was less than 0.1 times compared to A. aegypti under laboratory conditions, this result is consistent with the tendency to bite both species in nature. The target-attack frequency (foraging activity) in A. aegypti female mosquitoes in unfed conditions is 30 times greater than that of A. albopictus mosquitoes in several laboratory treatments (Kawada, et al. 2007). Aedes sp is a deadly infectious vector between another dengue hemorrhagic fever (DHF) and chikungunya. Pineleng is a marginal/suburban area of Station 1. Recent studies have reported changes in habitat patterns of Aedes sp, especially Aedes albopictus and Aedes aegypti . The aim of this study is to characterize the population density of the Aagoan sp. Imago based on the time distribution and altitude of the sea surface. The population density characteristics of the Aedes spagoed imago captured inside and outside the room based on the time distribution in North Sulawesi. The stages of the study consisted of larvae surveying, larval extraction and analysis, and imago extraction and analysis. The results showed that the high population of Ae aegypti was at 8:00 a.m. to 10:00 p.m. in the morning and 14:00 to 16:00 p.m. in the afternoon before the afternoon. in the morning before noon and at 14:00 to 18:00 in the afternoon before evening.
Nutmeg (Myristica fragrans) Of North Minahasa Molecular Entication Based on chloroplast DNA of matK gene
Authors: Nanlohy Fanny Nella , Mokosuli Yermia Semuel
Published: September 2023

Plant Nutmeg (Myristica fragrans) is an endemic plant in Indonesia originating from Banda Maluku Province. Nutmegs have long been known to people as spices. The nutmeg plants have been cultivated in North Sulawesi for a long time. This research has been conducted to obtain the position of species and the reconstruction of the phylogenetic tree of nutmeg plant (Myristica fragrans) from North Minahasa based on chloroplast DNA of matK gene. This research uses a descriptive method with a laboratory experiment. Total DNA was obtained by leaf tissue extraction and purification. The matK gene was amplified using the PCR method and visualized with automatic electrophoresis, sequencing was performed at FIRST BASE Singapore. The result of the analysis of the gene sequence of North Min Minerals using Barcode Of Life Database (BOLD) Systems shows that Pala Wori and Pala Patokaan have 99% similarity with Myristica maingayi and Myristica glubosa. While the reconstruction of the phylogeny tree shows the North Minahasa Pala has the closest resemblance to Myristica fatua.
THE BIOACTIVE CONTENT AND ANTIOXIDANT ACTIVITY OF HONEY BEEHIVES (Apis dorsata BINGHAMI) FROM THE BOGANI NANI WARTABONE BOLAANG MONGONDOW NATIONAL PLANT
Authors: Mokosuli Yermia S , Sumampouw Herry , Maliangkay Hendra Pratama , Langi Jimmy
Published: September 2023

Bee Honey (Apis dorsata Binghami) Is a subspecies of A. dorsata which is only found in sulawesidan island and surrounding islands and until now has not been successfully cultivated. Various studies have been conducted species of trees used for nesting places, nesting behavior, biotic conditions, physical surrounding nesting trees and nesting characteristics. This study aims to obtain secondary metabolite components and scientific data of antioxidant activity of honeybee extract (Apis dorsata Binghami) derived from Bogani Nani Wartabone Bolaang Mongondow National Park, North Sulawesi Province. The method of extraction in this research was conducted using maceration with methanol solvent, phytochemical test and antioxidant activity analysis using method (1,1-definil-2-picrilhidrazil) by measuring absorbance absorption at maximum wavelength using UV-Vis spectrophotometer. The results of the phytochemical test show that the honeycomb (Apis dorsata Binghami) contains alkaloids, flavonoids, saponins and tannins. From the analysis results showed that with the increasing concentration of extracts, the greater the antioxidant activity is marked by decreasing the value of IC50. The honeycomb (Apis dorsata Binghami) has IC50 of 212.42 ppm in comparison with vitamin C IC50 of 59.34 ppm
Application Of Apis dorsata Binghami Bee Nest Extract On The Effects Of Human Blood Lipid Reduction
Authors: Munawaroh Dina , Mokosuli Yermia S , Tengker Anita C. C.
Published: September 2023

Honey, royal jelly, bee pollen, bee wax, propolis, bee glue, and bee venom/ apitoxin are among the items produced by honey bees. Honey, pollen, bees, eggs, larvae, and pupae are all stored in the A. dorsata Binghami beehive. Secondary metabolites and bioactive phenolic compounds (phenols, phenolic acids, esters, flavors, dihydroflavones, flavanols, chalcones, and phenolic glycerides), essential oils (mono and sesquiterpenes), polysaccharides, amino acids, amines, lactones, quinones, steroids, and vitamins) can all be found in honeycomb. The goal of this study is to see how A. dorsata Binghami honeycomb tea affects blood lipid levels in humans after 14 days of consumption in a small group of male and female volunteers who were given a 2 gram tea bag extract of A. dorsata Binghami honeycomb simplicia to drink once a day to see how it affects lipid levels (total cholesterol, LDL, HDL, and TAG) in human blood. Total cholesterol (140.56 mg/dL), triglycerides (140.93 mg/dL), LDL (85.92 mg/dL), and HDL (21.49 mg/dL) were all found to be high in humans. As a result, "The Use of A. dorsata Binghami's Honeycomb Extract on the Effect of Reducing Human Blood Lipids" can lower lipid levels.
BIOAKTIVASI LARVASIDA NYAMUK Aedes sp. DARIiEKSTRAK DAUNiECENGiGONDOK (Eichhornia crassipes (Mart.) Solms) DARI DANAUiTONDANO
Authors: Polandos Jonathan , Mege Revolson Alexius , Mokosuli Yermia
Published: September 2023

Nyamuk Aedes sp. adalah vektor utama penyakit demam berdarah dengue yang mempunyai kiprah besar  pada terhadap penyebaran penyakit DBD di Indonesia. Pengendalian penyebaran vektor nyamuk dibutuhkan  agar dapat menurunkan populasi vektor nyamuk Aedes sp. sehingga dapat menurukan masalah penyebaran DBD. Salah satu pengendalian vektor penyakit DBD yaitu mengunakan larvasida yang berasal dari tumbuhan. Ekstrak alkohol daun eceng gondok (Eichhornia crassipes (Mart.) Solms) diduga memiliki pengaruh  larvasida Aedes sp., sebab mempunyai kandunan flavonoid, saponin dan  tanin yang mengganggu perkembanan larva nyamuk Aedes sp. Tujuan dari penelitian ini untuk mengetahui efetivitas ekstrak (crude extract) alkohol 70% daun eceng gondok (Eichhornia crassipes (Mart.) Solms) terhadap mortalitas larva nyamuk Aedes sp. Penelitian  eksperimental dilakukan dengan subyek dari penelitian yaitu 150 larva nyamuk Aedes sp. instar 3. Subyek penelitian dibagi menjadi lima grup pelakuan, konsentrasi kandungan yang digunakan di penelitian adalah 1000 ppm, 1500ppm, 2000 ppm, 2500ppm dan untuk kontrol positif adalah abate 1%. Pengamatan dilakukan 1x24 jam di ke 24 jam setelah perlakuan, perlakuan dilakukan replikasi sebanyak 3 kali. Data dianlisis serta dilakukan penghitungan nilai Lethal consentration mengunakan analisis probit. Berdasarkan analisis probit tidak ditemukan nilai dari LC50 di seluruh konsentrasi. Ekstrak (crude extract) alkohol 70% daun eceng gondok (Eichhornia crassipes (Mart.) Solms) tidak mempunyai efek larvasida nyamuk Aedes sp. Kesimpulan ekstrak  (crude extract) alkohol 70% Daun eceng gondok (Eichhornia crassipes (Mart.) Solms) tidak mampu membunuh  nyamuk vektor penyakit DBD nyamuk Aedes sp. di seluruh tingkat konsentrasi  sesudah dilakukan pengamatan selama 24 jam.
Ứng dụng nguyên tắc bơm hút chân không trong chế tạo thiết bị hút cá cơm
Authors: Nguyễn Văn Hân
Published: September 2023

Bài báo trình bày kết quả của nghiên cứu ứng dụng nguyên tắc bơm hút chân không để chế tạo thiết bị hút cá cơm. Với điều kiện ban đầu của bài toán là: công suất của bơm là 15m³/h; đường kính ống hút ϕ = 75 mm; chiều dài ống hút vào là l=6m và khối lượng riêng của hỗn hợp cá nước là γ = 2350 kg/m³ thì chiều cao cột áp hút là 1,7 mét.
Nghiên cứu tạo vật liệu ban đầu phục vụ chọn giống tôm sú (Penaeus monodon)
Authors: Nguyễn Hữu Hùng , Nguyễn Văn Hảo , Lại Văn Hùng , Phan Minh Quý , Đinh Hùng
Published: September 2023

Bài báo trình bày kết quả nghiên cứu đánh giá các đàn tôm vật liệu phục vụ tạo quần đàn ban đầu cho chọn giống nâng cao sinh trưởng tôm sú (Penaeus monodon). Bốn đàn tôm đã được thu thập phục vụ nghiên cứu gồm tôm tự nhiên từ Thái Lan (A), tôm tự nhiên từ Singapore (T), tôm tự nhiên ở Việt Nam (N) và tôm Gia hóa (G). Tổng số 69 gia đình tôm sú thuộc 16 tổ hợp lai đã được sản xuất. Tỷ lệ tôm cái đàn A và N đóng góp vào các tổ hợp lai chiếm tỷ lệ lớn nhất tương ứng 34,5% và 30,9%. Có sự chênh lệch lớn về tỷ lệ tham gia của vật liệu di truyền giữa tôm cái (tôm mẹ) và tôm đực (tôm bố) trong cùng một đàn tôm. Sự chênh lệch cũng thể hiện rõ ở tỷ lệ tham gia của tôm mẹ đàn A (34,5% ) so với đàn G (10,9%); và tôm bố đàn A (18,9%) so với đàn G (30,2%). Tỷ lệ trung bình của vật liệu di truyền tham gia vào các tổ hợp lai của đàn tôm gia hóa (G) thấp nhất so với các đàn tôm có nguồn gốc tự nhiên còn lại. Tôm thế hệ G0 được nuôi đánh giá sinh trưởng trong bốn môi trường nuôi khác nhau bao gồm bể nuôi tuần hoàn an toàn sinh học trong nhà, nuôi trong ao tại Khánh Hòa (miền Trung), Bạc Liêu (miền Tây Nam Bộ) và Vũng Tàu (miền Đông Nam Bộ). Kết quả nuôi và đánh giá cho thấy tất cả tương quan kiểu gen (rg) đều là tương quan thuận (> 0) và nằm ở mức từ 0,29 - 0,85. Tương quan kiểu gen (rg) giữa môi trường nuôi trong nhà cho chọn giống và ba môi trường nuôi ao thực tế tại Khánh Hòa, Bạc Liêu và Vũng Tàu thấp tương ứng 0,70, 0,42 và 0,29. Kết quả nghiên cứu cho phép dự đoán có tương tác G × E ở mức độ nhẹ.
Nghiên cứu đánh giá hiện trạng bảo vệ nguồn lợi hải sản vùng biển ven bờ tỉnh Quảng Nam
Authors: Phạm Viết Tích , Trần Đức Phú , Đỗ Văn Thành , Nguyễn Phi Toàn , Nguyễn Đình Phùng , Tô Văn Phương
Published: September 2023

Nghiên cứu đã sử dụng phương pháp điều tra và khảo sát hoạt động khai thác và bảo vệ nguồn lợi hải sản (NLHS) ở vùng biển ven bờ tỉnh Quảng Nam. Kết quả nghiên cứu cho thấy, đội ngũ cán bộ thanh tra của tỉnh còn thiếu, cơ sở vật chất không đầy đủ. Hoạt động thanh tra bảo vệ NLHS tỉnh Quảng Nam được đánh giá là thực hiện khá tốt, công tác tuyên truyền phổ biến chính sách và quy định của Nhà nước về khai thác hải sản được thực hiện khá đầy đủ. Tuy nhiên, tình trạng vi phạm quy định vẫn diễn ra ở một số nghề khai thác: khoảng 92,0% tàu cá vi phạm quy định về kích thước mắt lưới tối thiểu được phép sử dụng; 30,0% tàu cá vi phạm quy định về ngư trường và có 31,3% số người được hỏi sử dụng ngư cụ cấm trong khai thác hải sản. Nguyên nhân chính là: ý thức người dân chưa cao (chiếm khoảng 47,7% trường hợp); việc quản lý của đội ngũ cán bộ còn yếu (chiếm khoảng 50,8% số người được hỏi) và 9,2% người được hỏi cho rằng công tác tuyên truyền của địa phương đến người dân chưa được tốt.
On the simplicity crossed polymodules
Authors: DEHGHANİZADEH Mohammad Ali
Published: September 2023

The conception of crossed modules was first expressed by Whitehead when he was working on combinatorial theory. This concept has many uses in various fields, such as category theory, algebra, and k-theory. Moreover, one of the equations that plays a very important role in mathematical problems is the Yang-Baxter equation. In fact, although it doesn't seem like it, these equations play an effective role in studies such as particle physics, statistical mechanics, quantum field theory, and quantum groups. We use crossed modules to solve them. In crossed modules, the Actor was defined by Alp. Nilpotent, Solvable, $n$-Complete, and Representations of crossed modules were studied by Dehghanizadeh and Davvaz. In studies of group theory, a simplicial group is an object. Davvaz and Alp studied simplicial polygroups, and the generalized Moore complexes. They proved the existence of a functor from the category cat$^1$-polygroups to the category of groups and, furthermore, conversely. In this paper, we provide simplicity-crossed polymodules and some of their properties. We have also presented a simple crossed polymodules theorem.
orchid ethnobotany of nepal
Authors: Manandhar Narayan
Published: September 2023

The study presents an account of 52 species of orchid under 31 genera which are used by different tribal and non-tribal rural communities for different purposes in Nepal. Altogether, 13 species are used for food, 42 for medicine and 2 species for other purposes. Most of the uses are found to be unreported from Nepal.
Making Atmospheres
Authors: Bahmann Dirk
Published: September 2023

This paper discusses a practical methodology, developed for a second-year architectural elective project, that aims to make tangible the qualities of architectural atmospheres. It argues for an embodied practice of making sculptural artefacts. It proposes that these can articulate and make apparent atmospheric qualities. To be able to imagine or recognise atmosphere is a crucial skill for architects since atmosphere determines how people respond to space. The methodology is designed, through iterative cycles of making and critical reflection, to make students increasingly aware of atmosphere and develop their ability to create and articulate certain feeling tones within spaces. This artistic praxis relies upon a nonlinear, bodily knowing that seeks to challenge the dominance of ocularcentric practice in the discipline of architecture.
Outcome of Suprachoroidal Triamcinolone Acetonide in Resistant Diabetic Macular Edema
Authors: Jamil Muhammad Hannan , Ashraf Aneeb , Khan Asmatullah , Ashraf Bilal , Afzal Muhammad Bilal , Shahbaz Ferheen
Published: September 2023

One of the most frequent cause of central vision deterioration in people with retinopathy due to diabetes is diabetic macular edema. Suprachoroidal injections offer a novel way of delivery for the administration of corticosteroids that may have various benefits. Objective: To observe outcome of triamcinolone acetonide given by suprachoroidal route for the treatment of resistant diabetic macular edema. Methods: A descriptive case series study which was carried out at Department of Ophthalmology, Layton Rahmatullah Benevolant Trust Hospital Multan Road Lahore from July 14, 2021 till Jan 14, 2022. A total of 60 cases meeting selection criteria was taken after taking approval from hospital ethical committee. All injections were given by a single surgeon to avoid any related bias. 30-gauge 1cc insulin syringe was used in all cases. Results: The study included patients aged between 30 and 70 years, and the average age was 52.73 ± 10.99 years. There were 39(65%) male with 21(35%) female cases. The average central subfield thickness before and after one month was 593.62 ± 116.87 µm and 303.55 ± 31.29 µm with statistically significantly less mean central subfield thickness after 1 month, p-value less than 0.001. The mean visual acuity after correction before and after one month was 0.81 ± 0.16 and 0.45 ± 0.03 respectively, with statistically significantly less mean optimally corrected visual acuity after 1 month, p-value less than 0.001. Conclusions: It was found that suprachoroidal triamcinolone acetonide is useful in managing the central subfield and optimally corrected visual acuity in resistant diabetic macular edema.
Level of Knowledge of Bedside Nursing Staff Regarding Phlebitis of a Tertiary Care Hospital, Karachi
Authors: Shaikh Muhammad Hasnain , Ali Rizwan , Ahmad Tufail , Manan Ahsan , Khan Ismail , Khan Muhammad Jehangeer , Bibi Afsha
Published: September 2023

Phlebitis is the inflammation of the vein's inner layer, venous tunica intima called phlebitis. The complications that commonly occur due to phlebitis are erythema, pain, swelling, and palpable thrombosis of the cannulated vein. Objective: To identify the current knowledge of bedside nursing staff regarding phlebitis. Methods: A cross-sectional study was carried out to find knowledge regarding phlebitis among nurses through self-administered questionnaires with 100 bedside nurses working in different wards of a Private Tertiary Hospital in Karachi, Pakistan, by a convenient sampling technique. Data were collected and analyzed by the SPSS software version-22. Results: The result of this study showed that among 100 participants, 50% participants have inadequate knowledge regarding phlebitis, 44% had average, and 6% had good knowledge regarding phlebitis. Conclusions: This study concluded that bedside staff nurses have insufficient knowledge regarding phlebitis. This poor knowledge can reduce the effectiveness of nursing care provided to the patient. Therefore, educational sessions and interventional study needed to enhance their knowledge regarding phlebitis.
Functional Exercise Capacity, Fatigue and Peripheral Muscle Strength in Patients with Obstructive Sleep Apnea Syndrome and Controls
Authors: Katayifci Nihan , Huzmeli Irem , Dikmen Nursel
Published: September 2023

Introduction: This Physical impairment in obstructive sleep apnea syndrome (OSAS) patients are still unclear. This study compared functional exercise capacity, dyspnea, fatigue, physical activity, quality of life, and respiratory and peripheral muscle strength in patients with OSAS and controls.
Materials and Methods: Twelve patients with OSAS and 24 controls were included. Functional exercise capacity [6-minute walking test (6-MWT)], dyspnea, peripheral muscle strength, fatigue, physical activity, quality of life, respiratory muscle strength, and excessive daytime sleepiness [The Epworth Sleepiness Scale (ESS)] were evaluated.
Results: The 6-MWT, physical activity level, peripheral muscle strength, and quality of life were lower; the level of fatigue and dyspnea were increased in patients with OSAS than in controls (p<0.05). Inspiratory and expiratory muscle strength were similar in patients with OSAS and controls (p>0.05). ESS was correlated with fatigue (p=0.036, r=0.608) and MMRC (p=0.018, r=0.665).
Conclusion: Patients had reduced functional exercise capacity, physical activity level, quality of life, peripheral muscle strength, and increased perception of fatigue and dyspnea than healthy controls. Cardiac rehabilitation programs should be added to the management of OSAS.
Evaluation of Postoperative Follow-ups of Children Having the Glenn Procedure
Authors: Talay Mehmet , Doyurgan Onur
Published: September 2023

Introduction: This study aimed to evaluate the treatment results, complications, and the factors affecting mortality in cases who were followed up postoperatively in the pediatric intensive care unit (PICU) after the Glenn shunt procedure.
Materials and Methods: The duration of the patients on the pump during surgery, transition times to feeding, blood gas and other laboratory parameters, complications developed during follow-up in the intensive care unit, and exitus rates were evaluated retrospectively.
Results: BDG was performed due to tricuspid atresia, the most common diagnosis (30.2%). In the evaluation of the relationship between postoperative patient findings and exitus, a positive correlation was found between the duration of inotropic support, early extubation, and the duration of HFNC therapy in all patients (p<0.05); and a negative correlation was found in terms of the fluid the patients received on the first day after surgery (p<0.05). In patients who developed complications, a negative correlation was observed only in terms of the fluid they received on the first day after surgery (p<0.05)
Conclusions: In terms of all patients, it was observed that mortality increased with early extubation and prolonged duration of inotropic support and HFNC therapy, and it decreased as the fluid the patients received on the first day after surgery decreased. In patients who developed complications, it was only observed that mortality decreased as the fluid the patients received on the first day after surgery decreased.
Analysis of Vaccination Status of Patients Admitted to the Intensive Care Unit with Confirmed COVID-19-Related ARDS: A Retrospective Cross-Sectional Study
Authors: Gunes Haci , Kurt Nurettin
Published: September 2023

Introduction: Although vaccination is considered the most effective and essential way to prevent and control COVID-19, immune responses may differ. This study investigated the relationship between vaccination status and gender, noninvasive ventilation (NIV) needs, intubation, length of stay in the intensive care unit (ICU), and mortality.
Materials and methods: During this study, 124 patients aged 18 years and older were admitted to the ICU. We analyzed data from 99 patients with confirmed COVID-19. The patients were divided into three groups according to their vaccination status: vaccinated (≥2 doses of vaccine), partially vaccinated (only one dose of vaccine), or unvaccinated. Vaccination status, age, gender, APACHE II, modified Charlson comorbidity index, need for NIV and intubation, date of intubation, length of stay in the ICU, and ICU outcome were recorded.
Results: A total of 99 patients were analyzed during the study period: 36 (36%) were vaccinated, 8 (8%) were partially vaccinated, and 55 (56%) were not vaccinated. The mean age was 58.7±18.8 years, and 51 (51.5%) were female. Comorbidity was present in 77% (n=76) of the patients. There was no correlation between vaccination status and gender (p=0.564), NIV needs (p=0.810), intubation (p=0.639), length of stay in the ICU (p=0.479), or mortality (p=0.769). The age (p=0.002), modified Charlson comorbidity index (p=0.002), APACHE II score at admission to the ICU (p=0.039), and creatinine (p=0.036) were higher in the vaccinated patients and were associated with mortality.
Conclusion: No correlation was found between vaccination status and gender, need for NIV, intubation, length of stay in the ICU, or mortality
Comparative Outcomes of Surgical Treatments for Primary Stress Urinary Incontinence in Women: A Retrospective Cohort Study
Authors: Dogan Kazim
Published: September 2023

Introduction: The study evaluates the outcomes of different surgical techniques, including Tension-free Vaginal Tape (TVT), Trans-Obturator Tape (TOT), Burch Colpopexy (BC), and Anterior Vaginal Wall Prolapse Repair (APR), in treating primary stress urinary incontinence (SUI) in women.
Materials and Methods: A retrospective cohort study was conducted in a tertiary care center, comprising 62 women diagnosed with primary SUI who underwent one of the aforementioned surgical procedures. Demographic and clinical variables were analyzed, including age, BMI, menopausal status, reproductive history, incontinence types, anticholinergic use, and preoperative assessments.
Results: No differences were found in age (p=0.227), weight (p=0.943), height (p=0.333), and BMI (p=0.642) among the four treatment groups. The distribution of menopausal patients and reproductive history variables did not differ among the groups. Postoperative anticholinergic prescription rates (p=0.769) and duration of use (p=0.531) were not different across the groups. The majority of patients in the TVT, TOT, and BC groups had a grade 2 cystocele (p=0.065). The BC group had 100% grade 1 rectocele, which was not significant compared to other groups (p=0.126).
Conclusion: Our results showed no potential difference in comparable outcomes among TVT, TOT, BC, and APR for the surgical treatment of primary SUI.