bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of cochlear modiolus dose on hearing preservation following stereotactic radiosurgery for non–vestibular schwannoma neoplasms of the lateral skull base: a cohort study
Authors: Carlstrom Lucas P. , Jacob Jeffrey T. , Graffeo Christopher S. , Perry Avital , Oldenburg Michael S. , Foote Robert L. , Pollock Bruce E. , Driscoll Colin L. , Carlson Matthew L. , Link Michael J.
Published: July 2019

OBJECTIVE

Radiation dose to the cochlea has been proposed as a key prognostic factor in hearing preservation following stereotactic radiosurgery (SRS) for vestibular schwannoma (VS). However, understanding of the predictive value of cochlear dose on hearing outcomes following SRS for patients with non-VS tumors of the lateral skull base (LSB) is incomplete. The authors investigated rates of hearing loss following high-dose SRS in patients with LSB non-VS lesions compared with patients with VS.

METHODS

Patients with LSB meningioma or jugular paraganglioma and serviceable pretreatment hearing who underwent SRS treatment during 2007–2016 and received a modiolus dose > 5 Gy were included in a retrospective cohort study, along with a similarly identified control group of consecutive patients with sporadic VS.

RESULTS

Sixteen patients with non-VS tumors and a control group of 43 patients with VS met study criteria. Serviceable hearing, defined as American Academy of Otololaryngology–Head and Neck Surgery class A/B, was maintained in 13 non-VS versus 23 VS patients (81% vs 56%, p = 0.07). All 3 instances of hearing loss in non-VS patients were observed in cerebellopontine angle (CPA) meningiomas. Non-VS with preserved hearing had a median modiolus dose of 6.9 Gy (range 5.7–19.2 Gy), versus 7.4 Gy (range 5.4–7.6 Gy) in those patients with post-SRS hearing loss (p = 0.53). Sporadic VS patients received an overall median modiolus point-dose of 6.8 Gy (range 5.4–11.7 Gy).

CONCLUSIONS

The modiolus dose threshold of 5 Gy does not predict hearing loss in patients with non-VS tumors undergoing SRS, suggesting that dosimetric parameters derived from VS may not be applicable to this population. Differential rates of hearing loss appear to vary by pathology, with paragangliomas and petroclival meningiomas demonstrating decreased risk of hearing loss compared to CPA meningiomas that may directly compress the cochlear nerve similarly to VS.
Antithrombotic agents and traumatic brain injury in the elderly population: hemorrhage patterns and outcomes
Authors: Scotti Pasquale , Séguin Chantal , Lo Benjamin W. Y. , de Guise Elaine , Troquet Jean-Marc , Marcoux Judith
Published: July 2019

OBJECTIVE

Among the elderly, use of antithrombotics (ATs), antiplatelets (APs; aspirin, clopidogrel), and/or anticoagulants (ACs; warfarin, direct oral ACs [DOACs; dabigatran, rivaroxaban, apixaban]) to prevent thromboembolic events must be carefully weighed against the risk of intracranial hemorrhage (ICH) with trauma. The goal of this study was to assess the risk of sustaining a traumatic brain injury (TBI), ICH, and poorer outcomes in relation to AT use among all patients 65 years or older presenting to a single institution with head trauma.

METHODS

Data were collected from all head trauma patients 65 years or older presenting to the authors’ supraregional tertiary trauma center over a 24-month period and included age, sex, injury mechanism, medical history, international normalized ratio, Glasgow Coma Scale (GCS) score, ICH presence and type, hospital admission, reversal therapy, surgery, discharge destination, Extended Glasgow Outcome Scale (GOSE) score at discharge, and mortality.

RESULTS

A total of 1365 head trauma patients 65 years or older were included; 724 were on AT therapy (413 on APs, 151 on ACs, 59 on DOACs, 48 on 2 APs, 38 on AP+AC, and 15 on AP+DOAC) and 641 were not. Among all head trauma patients, the risk of sustaining a TBI was associated with AP use after adjusting for covariates. Of the 731 TBI patients, those using ATs had higher rates of ICH (p <0.0001), functional dependency at discharge (GOSE score ≤ 4; p < 0.0001), and mortality (p < 0.0001). Elevated rates of ICH progression on follow-up CT scanning were observed in patients in the warfarin monotherapy (OR 5.30, p < 0.0001) and warfarin + AP (OR 6.15, p = 0.0011). Risk of mortality was not associated with single antiplatelet use but was notably high with 2 APs (OR 4.66, p = 0.0056), warfarin (OR 5.18, p = 0.0003), and DOAC use (OR 5.09, p = 0.0149).

CONCLUSIONS

Elderly trauma patients on ATs, especially combination therapy, are at elevated risk of ICH and poor outcomes compared with those not on AT therapy. While both AP and warfarin use alone and in combination were associated with significantly elevated odds of sustaining an ICH among TBI patients, only warfarin use was a predictor of hemorrhage progression on follow-up scans. The use of a single AP was not associated with mortality; however, the combination of both aspirin and clopidogrel was. Warfarin and DOAC users had comparable mortality rates; however, DOAC users had lower rates of ICH progression, and fewer survivors were functionally dependent at discharge than were warfarin users. DOACs are an overall safer alternative to warfarin for patients at high risk of falls.
A 360° electronic device for recording high-resolution intraoperative electrocorticography of the brain during awake craniotomy
Authors: ReFaey Karim , Chaichana Kaisorn L. , Feyissa Anteneh M. , Vivas-Buitrago Tito , Brinkmann Benjamin H. , Middlebrooks Erik H. , McKay Jake H. , Lankford David J. , Tripathi Shashwat , Bojaxhi Elird , Roth Grayson E. , Tatum William O. , Quiñones-Hinojosa Alfredo
Published: July 2019

OBJECTIVE

Epilepsy is common among patients with supratentorial brain tumors; approximately 40%–70% of patients with glioma develop brain tumor–related epilepsy (BTRE). Intraoperative localization of the epileptogenic zone during surgical tumor resection (real-time data) may improve intervention techniques in patients with lesional epilepsy, including BTRE. Accurate localization of the epileptogenic signals requires electrodes with high-density spatial organization that must be placed on the cortical surface during surgery. The authors investigated a 360° high-density ring-shaped cortical electrode assembly device, called the “circular grid,” that allows for simultaneous tumor resection and real-time electrophysiology data recording from the brain surface.

METHODS

The authors collected data from 99 patients who underwent awake craniotomy from January 2008 to December 2018 (29 patients with the circular grid and 70 patients with strip electrodes), of whom 50 patients were matched-pair analyzed (25 patients with the circular grid and 25 patients with strip electrodes). Multiple variables were then retrospectively assessed to determine if utilization of this device provides more accurate real-time data and improves patient outcomes.

RESULTS

Matched-pair analysis showed higher extent of resection (p = 0.03) and a shorter transient motor recovery period during the hospitalization course (by approximately 6.6 days, p ≤ 0.05) in the circular grid patients. Postoperative versus preoperative Karnofsky Performance Scale (KPS) score difference/drop was greater for the strip electrode patients (p = 0.007). No significant difference in postoperative seizures between the 2 groups was present (p = 0.80).

CONCLUSIONS

The circular grid is a safe, feasible tool that grants direct access to the cortical surgical surface for tissue resection while simultaneously monitoring electrical activity. Application of the circular grid to different brain pathologies may improve intraoperative epileptogenic detection accuracy and functional outcomes, while decreasing postoperative complications.
Gamma Knife radiosurgery for the treatment of Nelson’s syndrome: a multicenter, international study
Authors: Cordeiro Diogo , Xu Zhiyuan , Li Chelsea E. , Iorio-Morin Christian , Mathieu David , Sisterson Nathaniel D. , Kano Hideyuki , Attuati Luca , Picozzi Piero , Sheehan Kimball A. , Lee Cheng-chia , Liscak Roman , Jezkova Jana , Lunsford L. Dade , Sheehan Jason
Published: July 2019

OBJECTIVE

Nelson’s syndrome is a rare and challenging neuroendocrine disorder, and it is associated with elevated adrenocorticotrophic hormone (ACTH) level, skin hyperpigmentation, and pituitary adenoma growth. Management options including resection and medical therapy are traditional approaches. Ionizing radiation in the form of Gamma Knife radiosurgery (GKRS) is also being utilized to treat Nelson’s syndrome. In the current study the authors sought to better define the therapeutic role of stereotactic radiosurgery (SRS) in Nelson’s syndrome.

METHODS

Study patients with Nelson’s syndrome were treated with single-fraction GKRS (median margin dose of 25 Gy) at 6 different centers as part of an International Radiosurgery Research Foundation (IRRF) investigation. Data including neurological function, endocrine response, and radiological tumor response were collected and sent to the study-coordinating center for review. Fifty-one patients with median endocrine and radiological follow-ups of 91 and 80.5 months from GKRS, respectively, were analyzed for endocrine remission, tumor control, and neurological outcome. Statistical methods were used to identify prognostic factors for these endpoints.

RESULTS

At last follow-up, radiological tumor control was achieved in 92.15% of patients. Endocrine remission off medical management and reduction in pre-SRS ACTH level were achieved in 29.4% and 62.7% of patients, respectively. Improved remission rates were associated with a shorter time interval between resection and GKRS (p = 0.039). Hypopituitarism was seen in 21.6% and new visual deficits were demonstrated in 15.7% of patients.

CONCLUSIONS

GKRS affords a high rate of pituitary adenoma control and improvement in ACTH level for the majority of Nelson’s syndrome patients. Hypopituitarism is the most common adverse effect from GKRS in Nelson’s syndrome patients and warrants longitudinal follow-up for detection and endocrine replacement.
Extent of resection of epidermoid tumors and risk of recurrence: case report and meta-analysis
Authors: Shear Brian M. , Jin Lan , Zhang Yawei , David Wyatt B. , Fomchenko Elena I. , Erson-Omay E. Zeynep , Huttner Anita , Fulbright Robert K. , Moliterno Jennifer
Published: July 2019

OBJECTIVE

Intracranial epidermoid tumors are slow-growing, histologically benign tumors of epithelial cellular origin that can be symptomatic because of their size and mass effect. Neurosurgical resection, while the treatment of choice, can be quite challenging due to locations where these lesions commonly occur and their association with critical neurovascular structures. As such, subtotal resection (STR) rather than gross-total resection (GTR) can often be performed, rendering residual and recurrent tumor potentially problematic. The authors present a case of a 28-year-old man who underwent STR followed by aggressive repeat resection for regrowth, and they report the results of the largest meta-analysis to date of epidermoid tumors to compare recurrence rates for STR and GTR.

METHODS

The authors conducted a systemic review of PubMed, Web of Science, and the Cochrane Collaboration following the PRISMA guidelines. They then conducted a proportional meta-analysis to compare the pooled recurrence rates between STR and GTR in the included studies. The authors developed fixed- and mixed-effect models to estimate the pooled proportions of recurrence among patients undergoing STR or GTR. They also investigated the relationship between recurrence rate and follow-up time in the previous studies using linear regression and natural cubic spline models.

RESULTS

Overall, 27 studies with 691 patients met the inclusion criteria; of these, 293 (42%) underwent STR and 398 (58%) received GTR. The average recurrence rate for all procedures was 11%. The proportional meta-analysis showed that the pooled recurrence rate after STR (21%) was 7 times greater than the rate after GTR (3%). The average recurrence rate for studies with longer follow-up durations (≥ 4.4 years) (17.4%) was significantly higher than the average recurrence rate for studies with shorter follow-up durations (< 4.4 years) (5.7%). The cutoff point of 4.4 years was selected based on the significant relationship between the recurrence rate of both STR and GTR and follow-up durations in the included studies (p = 0.008).

CONCLUSIONS

STR is associated with a significantly higher rate of epidermoid tumor recurrence compared to GTR. Attempts at GTR should be made during the initial surgery with efforts to optimize success. Surgical expertise, as well as the use of adjuncts, such as intraoperative MRI and neuromonitoring, may increase the likelihood of completing a safe GTR and decreasing the long-term risk of recurrence. The most common surgical complications were transient cranial nerve palsies, occurring equally in STR and GTR cases when reported. In all postoperative epidermoid tumor cases, but particularly following STR, close follow-up with serial MRI, even years after surgery, is recommended.
Infuse-as-you-go convective delivery to enhance coverage of elongated brain targets: technical note
Authors: Sudhakar Vivek , Naidoo Jerusha , Samaranch Lluis , Bringas John R. , Lonser Russell R. , Fiandaca Massimo S. , Bankiewicz Krystof S.
Published: July 2019

OBJECTIVE

To develop and assess a convective delivery technique that enhances the effectiveness of drug delivery to nonspherical brain nuclei, the authors developed an occipital “infuse-as-you-go” approach to the putamen and compared it to the currently used transfrontal approach.

METHODS

Eleven nonhuman primates received a bilateral putamen injection of adeno-associated virus with 2 mM gadolinium-DTPA by real-time MR-guided convective perfusion via either a transfrontal (n = 5) or occipital infuse-as-you-go (n = 6) approach.

RESULTS

MRI provided contemporaneous assessment and monitoring of putaminal infusions for transfrontal (2 to 3 infusion deposits) and occipital infuse-as-you-go (stepwise infusions) putaminal approaches. The infuse-as-you-go technique was more efficient than the transfrontal approach (mean 35 ± 1.1 vs 88 ± 8.3 minutes [SEM; p < 0.001]). More effective perfusion of the postcommissural and total putamen was achieved with the infuse-as-you-go versus transfronatal approaches (100-µl infusion volumes; mean posterior commissural coverage 76.2% ± 5.0% vs 32.8% ± 2.9% [p < 0.001]; and mean total coverage 53.5% ± 3.0% vs 38.9% ± 2.3% [p < 0.01]).

CONCLUSIONS

The infuse-as-you-go approach, paralleling the longitudinal axis of the target structure, provides a more effective and efficient method for convective infusate coverage of elongated, irregularly shaped subcortical brain nuclei.
The general concept of block-modular construction of forest tillage tools
Authors: Bartenev I. M , Lysych M. N
Published: July 2019

The article provides general data on the scale and prospects for the use of block-modular principles for constructing technical objects in various industries, in particular, in agriculture in the development of tillage and sowing units. In forestry, the block-modular construction of tillage tools has not found a wide-spread use, therefore, designs adapted to perform a single technological operation within a specific tech-nology prevail. At the same time, all this variety of specialized machines remains unclaimed, since Forest enterprises at the present stage of development are not capable of purchasing and operating a wide range of equipment and are limited to a very narrow set of obsolete tillage tools. To solve these problems, the author applied block-modular principles for constructing technical objects for developing a set of tillage forest tools. A constructive description of the proposed basic modular platforms (single-bar rear-mounted, double-sided rear-hung and front-hung) and various interchangeable modules of the working bodies is given. The possible options for the layout of modular tools in 3D CAD software SolidWorks have been worked out and an example of machine tractor unit based on a multifunctional modular plow has been presented. The analysis of the structures confirmed that the tools equipped with various working modules are capable of effectively performing all operations on basic soil preparation, carrying out agrotechnical treatments, as well as partly sowing and planting of forest crops in various conditions. Thus, a large variety of used forest tillage equipment used can be reduced to a narrow range of highly adaptable modular tools.
Computer simulation of the «engine - working machine» mechanical system
Authors: Delyagin V. N , Dobrolyubov I. P
Published: July 2019

There was investigated the application for the purpose of diagnosing the technical condition of the unit, the internal combustion engine (ICE) - the working machine (WM) of advanced computer models of internal combustion engines with the additional function of determining the technical condition of machines (mechanisms) driven by the internal combustion engine. The mechanical system «ICE-working machine» is considered as a three- and two-mass system with lumped parameters. Equations of equilibrium moments are made that act on the selected concentrated masses, taking into account various nonlinearities (dry and viscous friction, dead zone, etc.), elasticity of the shafts and joints. The block diagrams of the ICE-PM system in the form of transfer functions are given. A computer simulation of this system was carried out with the presentation of the obtained computer structural diagrams and graphs of dynamic processes (angular velocities and shaft accelerations, etc.). Introducing into these schemes the values of the parameters characteristic of a specific unit ICE-PM by varying the values of different moments, it is possible in the static and dynamic modes to evaluate their influence on the technical state of ICE-PM. The use of a computer model allows to take into account the influence of these factors on informative diagnostic signals reflecting the technical condition of the internal combustion engine, since the level of signals characterizing the power indicators of the internal combustion engine is significantly higher than the level of signals reflecting elasticity and nonlinearity. The developed computer block diagram can be directly used in diagnostic complexes based on microprocessor systems, microcontrollers and microcomputers for diagnosing internal combustion engines and working machines under operational conditions.
Brake force of tracked vehicles
Authors: Kopotilov V. I
Published: July 2019

It is commonly supposed that the slowing down and stopping of vehicle is caused by adhesion of its tracks to the dirt surface. However, force analysis shows that, although these forces play an important role during braking, the longitudinal components of the internal forces applied to the shafts of the vehicle’s braked drive wheels and the front support rollers of the tracked propulsion are directly responsible for its deceleration. The sum of these longitudinal forces directed against the motion of the tracked vehicle constitutes the braking force of the tracked vehicle. The value of this total braking force is ultimately determined by the ratio of the braking torque developed by the friction forces to the radius of the drive wheels with which the braking devices are coupled. Since when braking a tracked vehicle, the longitudinal reaction is balanced, it cannot be the direct cause of the deceleration of the vehicle, i.e. its braking force. In addition, the longitudinal reaction applied to the lower fixed part of the track does not perform mechanical work and cannot absorb the kinetic energy of a moving vehicle. This work is performed by the internal braking force Ртор, which develops negative (braking) power during braking. It turns out that during braking, the longitudinal reaction is needed not at all to cause a slowdown, but as an external force, to balance some of the internal forces of the tracked vehicle. As a result of its action, the unbalanced part of the internal forces forms the internal braking force, which directly causes the machine to slow down and stop. In this case, the longitudinal reaction of the supporting surface, without which the formation of an internal braking force is not possible, limits both the lower and upper values of the latter, and these forces themselves are numerically equal. The fact that the braking force of a tracked vehicle, like its traction force, is an internal force, does not contradict theorems on the movement of the center of mass or the change in the amount of motion of a mechanical system, which are valid only for isolated mechanical systems that do not have a source of active internal forces.
Features of the spectra of loads on the units of mobile agricultural machines in the field when delay in external influences
Authors: Partko S. A , Groshev L. M , Sirotenko A. N , Vojnash S. A
Published: July 2019

The problem of choosing the oscillatory parameters of mobile combine harvesters leads to the development of dynamic models that ensure the normal functioning of machines, as well as to consider these parameters in the probabilistic aspect and, consequently, to assess their dispersion. The main type of impact is the impact created by the unevenness of the path of the mobile machine and the change in the physical and mechanical characteristics of the soil. Such problems are solved with sufficient accuracy for practice in the linear formulation. In the article, external influences in multidimensional dynamic systems are presented in matrix form. Matrix of spectral densities when calculation of statistical characteristics in the presence of mutual relationships lead to the need to calculate the elements of both the main and secondary diagonals, which leads to the complication of calculations. Calculation of correlations between impacts determines the form of the matrix of spectral densities of external influences. When calculating statistical characteristics, relations taken into account lead to a complication of calculations. Therefore, it is advisable to bring the matrix of external influences to a diagonal form in order to obtain matrices of uncorrelated influences. The calculations of the spectral densities and vibrational intensities for mobile machines of the agroindustrial complex made it possible to establish that the same results are obtained only for vehicles with weak functional connections, when moving along a field micro profile creating an uncorrelated external influence. Recommendations on the practical use of calculation formulas are given.
Regulation of tractor diesel engine operation modes by missing fuel distribution
Authors: Potapov V. I , Gajsin E. H.M , Galiullin R. R , Rozhkov A. S
Published: July 2019

The article discusses the improvement of the effective performance of diesel engines of tractors at idle and low loads. A possible way to improve performance in such modes is deactivation of cylinders. However, this method of regulation has a number of disadvantages, in particular, a step change in the characteristic of specific fuel consumption. The goal is to increase the fuel efficiency of tractor diesel en-gines when regulating the operation modes by switching off the cylinders. Studies were conducted on tractor diesel engines 2Ch105х120 and 4Ch105х120, equipped with distribution pumps of dispenser type. Tests of 2Ch105х120 and 4Ch105х120 diesel engines showed that as the cylinders were disconnected, the engine efficiency reduced even at low loads. Upon further testing, it turned out that in order to achieve the distribution effect of the cylinder shutdown needed when working with the pump of the distribution type, a cyclic fuel supply correction to the operating cylinder is required. A characteristic feature of distribution type pumps was that shutting off the supply to one cylinder significantly changed the cycle flow to the other remaining cylinder. In one case, it turned out to be more than the required one and with its decrease, the specific fuel consumption decreased. In another case, when the cycle feed was less, the specific fuel consumption could be possible to reduce by its increasing. It turned out that with a simple shutdown of the cylinders, there remains an unrealized zone in which you can additionally receive fuel economy. One of the ways to implement this zone can be the transition from disconnecting cylinders to disconnecting individual fuel supplies. It is possible to implement this method by equipping the diesel fuel system with an electronically-controlled high-speed valve, which, depending on the engine's operating mode, will re-alize the necessary omission of fuel supply and adjustment of the cycle feed amount for individual cylin-ders. A Denso valve was used as a solenoid valve to shut off the fuel supply. An electronic regulator has been developed to control the operation of the cross-valve. The test results showed that when switching from simple shutdown of cylinders to regulating the operation modes by skipping individual fuel feeds, the specific fuel consumption changed smoothly and the power range at which the diesel engine operates in this mode remains the same as during work with all cylinders.
The influence of the angle of loosening of the working body of an agricultural instrument on the intensity of destruction of soil aggregates
Authors: Myalenko V. I
Published: July 2019

The consequence of mechanical tillage, in addition to achieving positive results, are also negative consequences associated with the destruction of the primary soil microaggregates. Some of the soil microaggregates that are in direct contact with the surface of the working body of the agricultural tools are crushed and destroyed. Directly microaggregate is a sustainable soil aggregate, or structural unit of ripe soil. In the center of the microaggregate there are solid particles of the parent rock, as a rule, these are SiO2 silica, around which there is a dense organic shell. The very fact of the destruction of the primary soil microaggregates in the treated soil layer is confirmed by the wear of the working bodies of agricultural tools, which are carried out by abrasive particles of the parent rock due to the destruction of the microaggregates themselves. It turns out that the intensity of wear of the working bodies indirectly characterizes the intensity of the destruction of soil microaggregates. As a result of the processing of ripe soils, its loosening in order to ensure at least 50 % of porosity, simultaneously grinding, destroys a certain layer of the structure of the aggregate structure of the same soil. These contradictions form the problem of finding a solution, reducing the possibility of destruction of the aggregate structure of the soil when it is processed by agricultural tools. The purpose of this work was to identify the influence of the geometrical parameters of the working bodies of agricultural tools on the intensity of destruction of microaggregates in the adjacent soil layer. This goal was achieved through theoretical studies and with the use of simulation laboratory tests, as a result of which the intervals of the geometric characteristics of the working bodies, at which the smallest destruction of soil microaggregates is achieved, are determined.
ANALISIS KINERJA INDUSTRI MANUFAKTUR DI JAWA TENGAH: APLIKASI DEA MODEL VRS
Authors: Samudro Bhimo Rizky , Pratama Yogi Pasca
Published: July 2019

This study aims to estimate the level of efficiency of the manufacturing industry in Central Java Province. The position of the manufacturing industry in Central Java between two clusters of Jakarta-Bandung and Surabaya were the justification for the urgency of this research. The concept of relative efficiency with format Constant Return to Scale (CRS) and the Variable Return to Scale (VRS) was used as the theoretical framework of this research. The concept was applied by the method of Data Envelopment analysis (DEA) to describe the level of efficiency of the manufacturing industry sub-sector in Central Java province in 2016. The study also describes a way of increasing efficiency in production output for the manufacturing sub-sector classified as inefficient. DEA model used in this study is the CRS and VRS with the orientation of the output (output-oriented)The results of this study indicate that the apparel sub-sector; wood and processing; machinery and equipment; as well as furniture and processing is a sub-sector of manufacturing industry in Central Java in 2016 were classified as inefficient. Sub sectors using too much input unit, thus creating inefficient production levels relative to other sub-sectors.
THE INFLUENCE OF WORK CULTURE, MOTIVATION AND COMPENSATION TO THE PERFOMANCE OF EMPLOYEES IN GOVERNMENT
Authors: Sulaeman Maman , Marlina Lina , Yuliani Gina Nur
Published: July 2019

The purpose of this study were to determine the effect of work culture, motivation and compensation to employee performance, to analyze the influence of corporate culture, motivation and compensation to employee performance. The object to be studied is the WTO (the regional organizations), which includes Office, the Environment Agency and the Office in the City of Tasikmalaya. The method used is descriptive method with survey method. The collection of data obtained by questionnaires, interviews, and literature. The population in this study is a civil servant at the Department, the Environment Agency and the office in the City of Tasikmalaya. By using path analysis, the results of this study showed that partially, workplace culture, motivation and compensation have a significant influence on employee performance. Simultaneously, work culture, motivation and compensation have a significant influence on employee performance, so the hypothesis is verified. This means that the work culture, motivation and compensation significantly influence employee performance.
ANALISIS SWOT SEBAGAI DASAR DALAM PENENTUAN STRATEGI PEMASARAN
Authors: Dasururi Rubait , Muzajjad Ach. , Mubarok Chilmy
Published: July 2019

This study aims to determine and analyze the presence and position of meatballs effort based on SWOT analysis and determine the right marketing strategy for your business based on the results of SWOT analysis meatballs. This research uses descriptive qualitative approach. The data used is qualitative data with the use of primary data and secondary data sources. The data collection is done by the method, triangulation namely, observation, interviews, and documentation. Data were analyzed by using analysis SWOT checking the validity of the findings to confirm the data of the study subjects. The findings are based on analysis of business meatballs SWOT have factored into strengths, namely cow wearing original raw materials, the processing is done by the business owner so that the owner can control according to the standards set. Meatball business opportunities are increasing as the holiday sales increase in class and Idul Fitri, and has a loyal customer. Threats to business meatballs are many competitors with a similar business, price competition, rising raw material products, differentiation of products made by competitors.
PENGARUH PEMBERIAN KREDIT USAHA EKONOMI PRODUKTIF TERHADAP PENINGKATAN PENDAPATAN MASYARAKAT
Authors: Jatmiko Anang Rohmad , Fathur Rohman Mohamad , M.Si Mas'adah
Published: July 2019

The purpose of this study was to determine the effect of micro-credit to the productive economy increase public revenues, to identify any obstacles in lending economically productive activities. The method used was a survey and interviews. Analysis of the data used statistical analysis. The results of his research are no significant influence of the credit to the improvement of people's income. As the amount of increase in public revenue that runs in line with the amount of credit, then increase the number of their loans to be more and more people will receive credit so that more and more people whose incomes rise. Obstacles encountered in lending is a discrepancy in lending, mistakes in lending, error target in lending to the target group, the competitor that lenders are the same, most people are reluctant to accept credit reasons cannot return, and society productive get credit easily from the savings and loan cooperatives that without using a complicated procedure with a high-interest rate.
PENGARUH DESAIN PRODUK DAN STRATEGI PEMASARAN TERHADAP KEPUTUSAN PEMBELIAN PRODUK
Authors: Dwiningwarni SS , Anjarsari Nur Maya , Syuhada' H.
Published: July 2019

This study aims to  analyze the impact of product design and marketing strategy to the purchasing decision partially, analyze the influence of design and marketing strategies on purchasing decisions simultaneously,  determine which variables are the dominant influence on purchasing decisions. The research approach used is positivism with quantitative data derived from respondents' answers collected through questionnaires. The method used is the Focus Group Discussion (FGD). The sampling technique used was simple random sampling and the number of samples taken as many as 100 respondents. Analysis of the data used is multiple linear regression with Ordinary Least Square method (OLS). The results of this study are the design of the product and marketing strategies significantly influence purchasing decisions partially, product design and marketing strategies significantly influence purchasing decisions simultaneously,  product design dominant influence on purchasing decisions. This means that companies must pay attention to the shape or design of a product to be manufactured or produced.
PENGARUH PERPUTARAN KAS DAN PERPUTARAN PIUTANG TERHADAP RENTABILITAS EKONOMI
Authors: Supriadi H. , Sapta W.P , Aslichah Hj.
Published: July 2019

This study aims to identify and analyze the influence of cash turnover and accounts receivable turnover simultaneously, identify and analyze the effect of cash turnover and accounts receivable turnover of the economic profitability partially, and determine the dominant factor affecting the economic profitability. This research was conducted in cooperation with the reason that the Cooperative is a service company and trade. This research was conducted quantitative descriptive approach. The data collection is done by means of documentation and interviews were unstructured. The data used are secondary data derived from study subjects. The analytical method used is multiple linear regression with Ordinary Least Square method. The findings of this study include are:  a significant difference between cash turnover and accounts receivable turnover of the economic profitability simultaneously. a significant difference between the cash turnover receivables turnover against economic profitability partially. Receivables turnover is a dominant factor affecting the economic profitability.
THE EFFECT OF INTERNAL AUDITORS AND INTERNAL CONTROL ON COMPANY PERFORMANCE (Case study in Sukoharjo Regency)
Authors: Murti Bayu , Wijayanti Anita , Masitoh Endang
Published: July 2019

The purpose of this study is (1) to determine the effect of internal auditors on Company Performance (2) to determine the effect of internal controls on company performance. This research was conducted in 4 manufacturing companies in Sukoharjo regency. The number of respondents in this study is 50 respondents from 50 questionnaires that have been distributed. Respondents in this study are internal auditor staff who work in a company. The method used is purposive sampling method. Data analysis method uses multiple linear regression analysis and the process of using SPSS 22. Determination of the coefficient of adjusted R Squared testing results of 0.37 indicates that 37% of the company's performance variables can be explained by internal auditor and internal control variables, while 63% is explained by factors other than research. From the tests that have been carried out f test and t-test, the research shows that (1) internal auditors affect the company's performance as evidenced by comparing the value of t count> t table at a significant 5% is 2,175> 2,0129 (2) internal control affects the company's performance with the proof proved by comparing the value of t count> t table at 5% significant is 4,751> 2,0129.
EFFECT OF FINANCIAL PERFORMANCE AND GOOD CORPORATE GOVERNANCE ON VALUE OF COMPANY
Authors: Ratnasari Diana , Chomsatu Samrotun Yuli , Wijayanti Anita
Published: July 2019

This study aimsato Determine and analyzeathe influence of financialaperformance (returnson investment and return on equity) and good corporate governance (managerial ownership, independent board of commissioner, and the auditacommittee) to the value of the company. The population insthissstudysaresallsmanufacturingscompaniedslistedsonsthesIndonesia Stock Exchange period 2014 to 2016. Sampling technique in this study using purposive samplingsmethod, Obtained a sample of 19 companies over three periods, the resulting in a total sample of 57. Data analysis techniques used is using multiplearegressionaanalysis. The results of the feasibility study models (F test) shows that the variables return on investment, return on equity, managerial ownership, independent boardaofaCommissioners, andatheaauditacommittee influence the value of the company. The result of hypothesis test (t test) shows that the variable of return on investment, return on asset, and independent board of commissioner influence to firm value, while managerial ownership variable and audit committee have no effect to company value.
THE INFLUENCE OF ACCOUNTING INFORMATION SYSTEMS, LEADERSHIP STYLE, WORK MOTIVATION ON EMPLOYEES PERFORMANCE
Authors: Endarwati S , Suhendro S , Dewi R. Riana
Published: July 2019

This study aims to test and analyze the effect of accounting information systems, leadership style and work motivation on performance garment company employees in sukoharjo.The population used in this research is the garment company employees at the accounting work on PT Danliris, PT Sunwoo Indonesia, and PT Panji Anom Setia in sukoharjo. Methods of data analysis used in this study is by purposive sampling. the number of respondents in this study as many as 38 of the 45 respondents number of questionnaires presented. Methods of analysis used was multiple linear regression analysis. The results showed that the accounting information system variables and influential work motivation and significantly to the variable performance of employees.  While variable leadership style has no effect against variable employee performance. the determination coefficients (R2) of 0.415. This indicates that variansi on a variable performance practice undertaken by the company in Sukoharjo garment amounted to 41.5% can be explained by the variable accounting information systems, leadership style and work motivation, whereas the remaining 58.5 % explained by factors – factors other than that examined
THE INFLUENCE OF EDUCATIONAL LEVEL, WORK EXPERIENCE AND COMPREHENSION OF ACCOUNTING INFORMATION SYSTEM ON FINANCIAL REPORT QUALITY
Authors: Adiyanto Fajar , Chomsatu Samrotun Yuli , Wijayanti Anita
Published: July 2019

This study is conducted to: 1) test and analyze the influence of educational level on financial report quality; 2) test and analyze the influence of work experience on financial report quality; 3) test and analyze the influence of accounting information system on financial report quality. This type of research i.e. research with quantitative data sources in this study is the primary data. Population in this study is all employees employed in district financial department in Surakarta with the sample amounted of 30 employees, where all population was taken as sample. The technique in this study use the question form. The data analysis in a linear regression multiple series program spss for windows version 17.0. From data analysis known that the variabel work experience (H2) and accounting information system comprehension (H3) have influence on financial report quality, and the educational level (H1) variable has no influence on financial report quality, with in the regression coefficient values show that showed a negative value i.e. t count-0.985 and significant value of 0.334
IMPLEMENTASI JOB ORDER COSTING METHOD DALAM PERHITUNGAN HARGA POKOK PRODUKSI MAP
Authors: Yulianti Ika , Masrunik Endah , Miftakhul Huda Anam , Elvianita Diana
Published: July 2019

This study aims to find a comparison of the calculation of the cost of goods manufactured in the CV. Mitra Setia Blitar uses the company's method and uses the Job Order Costing (JOC) method. The method used in this study is quantitative. The types of data used are quantitative and qualitative. Quantitative data is in the form of map production cost data while qualitative data is in the form of information about map production process. The result of calculating the cost of production of the map between the two methods results in a difference of Rp. 306. Calculation using the company method is more expensive than using the Job Order Costing method. Calculation of cost of goods manufactured using the company method is Rp. 2,205,000, - or Rp. 2,205, - each unit. While using the Job Order Costing (JOC) method is Rp. 1,899,000, - or Rp 1,899, - each unit. So that the right method used in calculating the cost of production is the Job Order Costing (JOC) method
TAX AWARENESS, MODERN TAX ADMINISTRATION SYSTEM AND TAX SANCTIONS AGAINST TAXPAYER COMPLIANCE
Authors: Saraswati Zulaicha Efrita , Masitoh Endang , Dewi Riana Rachmawati
Published: July 2019

The purpose of this research is to know the influence of the consciousness of tax, the tax administration system and modern taxation sanctions against taxpayer compliance. The sample used in this study the taxpayer in the city of Surakarta. The technique of sampling is done using a purposive sampling of the dwarf. The sample of respondents in the study were 40 tax payers. Methods of analysis used was multiple linear regression analysis. Results of the study the feasibility test model (F test) shows that the independent variable (the awareness of tax, the tax administration of the modern sisem and tax penalties) influential and significantly to the dependent variables (compliance with tax payers).  The results of the research hypothesis test (test t) indicates that the variable tax consciousness and modern tax administration system and significant effect against taxpayer compliance, while variable tax sanctions had no effect and no significant against taxpayer compliance.
ANALISIS PERBANDINGAN KINERJA KEUANGAN DENGAN METODE CAR ANTARA PT. BRI (Persero) Tbk DAN PT. BNI (Persero) Tbk YANG TERDAFTAR DI BEI
Authors: Karimah Anifatul , Dwiningwarni SS , Masyhadi H , Muhajir Ali
Published: July 2019

Banks are financial institutions that play an important role in the economy of a country. Therefore, the existence of a healthy bank is very necessary. This study aims to compare the financial performance of Indonesian people's banks (BRI) and Indonesian state banks (BNI) based on financial ratio analysis listed on the Indonesia Stock Exchange for the period 2012-2016. The study uses the CAR (Capital Adequacy Ratio) method in which the ratio shows how far all bank assets that contain risks (credit, participation, securities, bills at other banks) are also financed from the bank's own capital funds in addition to obtaining funds from sources sources outside the bank, such as community funds, loans (debts), etc. ... The results of this study indicate that the CAR ratio in BRI is better than that of BNI banks. This proves that the CAR ratio and financial performance at BRI banks are better than BNI banks. Because it can manage capital as well as possible and accommodate the risk of loss. The results also show that BRI is better known to the lower middle class.
ANALISIS KEPUTUSAN PEMBELIAN PAKET WISATA ALAM OLEH USER MEDIA SOSIAL INSTAGRAM
Authors: Purba Indra Setiawan , Ariwibowo Prasetio
Published: July 2019

The method used in this research is descriptive analysis method, regression analysis, and hypothesis testing with simple linier regression analysis and coefficient of determination analysis. In this study, the population is a student of Jakarta Capital City who has social media instagram and has never bought natural tourism package. The validity test used in this research is using Convirmatory factor analysis (CFA) technique. The low validity of a questionnaire instrument can be measured by loading factor with SPSS 20.00 for Windows.

Based on the results of simple regression calculation obtained a = 98.145 and b = 0.27 form regression Y = 98.145 + 0.27X. Interpretation of the regression equation model is any change of X variable scores for one unit, then the variable Y increases by 0.27 in the same direction with the constant 98.14 Provided Coefficient of Determination (KD) of 0.0225, this shows that the contribution of attitude on social media instagram (X ) to the decision of purchasing natural tourism package (Y) is equal to 2,25% and contribution by other factor equal to 97.75%. Based on t arithmetic <t table (1.485 <1.984), it means there is very low influence between attitude on social media instagram to decision of purchasing nature tour package.
INDIVIDUAL FACTORS THAT INFLUENCE THE ETHICAL BEHAVIOR OF ACCOUNTING STUDENT
Authors: Kusvanti HeniIkke , Suhendro Suhendro , Dewi Riana R
Published: July 2019

This research aims to find out how the influence of gender, ethical sensitivity, locus of control, and the understanding of the code of ethics the ethical behaviour against the accountant accounting students at universities in Surakarta. The population in this research are undergraduate students program of study had been completed accounting auditing courses at the Islamic University of Surakarta Batik, Slamet Riyadi, University and high school Economics. Sampling technique used was simple random sampling technique. Methods of analysis used was multiple linear regression analysis. The results of this research show that gender, ethical sensitivity and locus of control have no effect against the ethical behavior of college students in Surakarta. While the understanding of the code of ethics to ethical behavior of college students in Surakarta. The value of the coefficient of determination (R2) of 0.102. This indicates that the variansi variable on the practice of ethical behavior of college students in higher education in Surakarta amounted to 10.2% can be explained by the variable gender, ethical sensitivity, locus of control and understanding of the code of ethics of accountants, while the rest 89.8% is explained by factors – factors other than that examinedThis research aims to find out how the influence of gender, ethical sensitivity, locus of control, and the understanding of the code of ethics the ethical behaviour against the accountant accounting students at universities in Surakarta. The population in this research are undergraduate students program of study had been completed accounting auditing courses at the Islamic University of Surakarta Batik, Slamet Riyadi, University and high school Economics. Sampling technique used was simple random sampling technique. Methods of analysis used was multiple linear regression analysis. The results of this research show that gender, ethical sensitivity and locus of control have no effect against the ethical behavior of college students in Surakarta. While the understanding of the code of ethics to ethical behavior of college students in Surakarta. The value of the coefficient of determination (R2) of 0.102. This indicates that the variansi variable on the practice of ethical behavior of college students in higher education in Surakarta amounted to 10.2% can be explained by the variable gender, ethical sensitivity, locus of control and understanding of the code of ethics of accountants, while the rest 89.8% is explained by factors – factors other than that examined