bluuebunny/crossref_metadata_2025 huggingface dataset:
STRATEGI FUNDRAISING ZAKAT DI LEMBAGA RUMAH PEMBERDAYAAN UMMAT (RPU)
Authors: Wardhani Mustika Kusuma
Published: June 2022

The potential for zakat in Jatinom District itself is quite large. This can be seen from the condition of the community that the majority of the population is Muslim and some of the population is included in the category of prosperous society. However, this potential has not been fully explored because the level of public awareness in paying zakat is still low. In responding to this, the Rumah Pemberdayaan Ummat (RPU) Jatinom instituted a zakat fundraising strategy. Therefore, the purpose of this study is to find out how the zakat fundraising strategy is the Rumah Pemberdayaan Ummat (RPU) Jatinom and its obstacles. The type of research used is field qualitative research. Sources of data in this study are primary and secondary data sources. Primary sources were obtained from observations, interviews, with RPU Jatinom, then secondary sources were obtained from important supporting documents. After the data is collected, the next step is to go through the data reduction stage, data presentation and drawing conclusions. The zakat fundraising strategy of the Rumah Pemberdayaan Ummat (RPU) Jatinom is carried out through several methods, namely online methods and offline methods.
Potensi zakat di Kecamatan Jatinom sendiri cukup besar. Hal tersebut terihat dari kondisi masyarakat mayoritas penduduk beragama Islam serta sebagian penduduk termasuk dalam kategori masyarakat sejahtera. Akan tetapi, dari potensi tersebut belum dapat tergali secara maksimal karena tingkat kesadaran masyarakat dalam membayarkan zakatnya masih rendah. Dalam menjawab hal tersebut Lembaga Rumah Pemberdayaan Ummat (RPU) Jatinom melakukan strategi fundraising zakat. Maka dari itu tujuan dalam penelitian ini yaitu untuk mengetahui bagaimana strategi fundraising zakat Lembaga Rumah Pemberdayaan Ummat (RPU) dan hambatannya. Jenis penelitian yang digunakan adalah penelitian kualitatif lapangan. Sumber data dalam penelitian ini adalah sumber data primer dan sekunder. Untuk sumber primer didapatkan dari observasi, wawancara, dengan pihak RPU Jatinom, kemudian untuk sumber sekunder didapatkan dari dokumendokumen penting sebagai pendukung. Setelah data terkumpul, langkah berikutnya yaitu melalui tahap reduksi data, penyajian data dan penarikan kesimpulan. Strategi fundraising zakat Lembaga Rumah Pemberdayaan Ummat (RPU) dilakukan melalui beberapa metode yaitu metode secara online dan metode secara offline.
Evaluating the Safety and Efficacy of MSCs-derived Exosomes for Treatment of Refractory Perianal Fistula in IBD patients; Clinical Trial Phase I
Authors: Nazari Hojjatollah , Heirani Asieh , Soleimani Masoud , Asbagh Reza Akbari , hadizadeh Alireza , behboudi behnam , Fazeli Mohammad Sadegh , Rahimi Mojgan , Keramati Mohammad Reza , Keshvari Amir , Kazemeini Alireza , Alborzi Foroogh , tafti seyed mohsen ahmadi
Published: June 2022

Background and objectives:

Exosomes therapy is a promising technique that can decrease the concern
related to the fate of transplanted stem cells to the fistula location.
The unique properties of mesenchymal stem cells (MSCs)-derived exosomes
can improve fistula healing because of their high ability to regulate
and modify immune responses. This project aims to examine the safety and
efficacy of implementing MSCs-exosomes in treating refractory fistulas
in inflammatory bowel disease (IBD) patients.

Methods:

The exosomes were isolated from umbilical cord-derived MSCs and
characterized using flow cytometry, western blotting, and transmittance
electron microscope (TEM). Five patients (three men and two women) with
refractory perianal Crohn’s disease with an average age of 35.4 years
old were included. The patients did not match the exclusion criteria,
and the presence of refractory fistulas was the main inclusion criteria.
These patients have their exosomes injections in the operation room. The
therapy responses of patients were assessed using physical examination,
face-to-face interviews, computerized tomography (CT) scan, and magnetic
resonance imaging (MRI) six months later.

Result:

The Following injection, patients reported a 70% improvement on
average. Two patients claimed complete healing after exosome injections,
while one patient reported no improvement and active discharge from the
fistula site. In addition, five patients reported no adverse effects,
both systemic or on the injection site.

Conclusion: Injection of exosomes extracted from MSCs shows
total safety and a satisfactory therapeutic impact, as shown in this and
other research, and could play a significant role in the treatment of
gastrointestinal fistulas in the future.
Synthesis and biological activity of novel zingerone-thiohydantoin hybrids
Authors: Virijevic Katarina , Stanic Petar , Muskinja Jovana , Katanic-Stankovic Jelena , Sreckovic Nikola , Zivanovic Marko , Smit Biljana
Published: June 2022

A series of zingerone?thiohydantoin hybrids were synthesized from O-alkyl zingerone derivatives by cyclocondensation with thiosemicarbazide in a two-step reaction. The obtained new potentially bioactive compounds were structurally characterized by IR and NMR spectroscopy, as well as by elemental and HRMS analysis. In addition, their antimicrobial and in vitro anticancer activities were tested. The tested compounds showed low to moderate antimicrobial activity. Zingerone?thiohydantoin hybrid with an O-butyl substituent exerted the significant cytotoxic activity on colon HCT-116 cancer cells, without toxicity on healthy MRC-5 cells.
Audit Efficiency and Effectiveness Consequences of Accounting System Homogeneity across Audit Clients: A New Form of Knowledge Spillover?
Authors: Murthy Uday S. , Park Jong Chool , Smith Thomas , Whitworth James
Published: June 2022

We examine the effects of a large number of clients in an audit office using the same enterprise-resource planning (ERP) system such as SAP or Oracle resulting in what we term “client accounting system homogeneity” on audit efficiency and effectiveness. Using a unique dataset of ERP system implementations, we find that accounting system homogeneity is positively associated with audit efficiency. Specifically, we find lower (higher) audit fees for clients using an ERP system from a vendor used by a higher (lower) proportion of clients in that office. We further document that accounting system homogeneity is associated with improved audit effectiveness as proxied by two accruals-based measures, incorrect internal control weakness reporting, and restatements. Our findings are reflective of a new form of knowledge spillover from repeated experiences auditing clients using similar accounting systems, resulting in audits that are not only less expensive but also of higher quality.

Data Availability: Contact the authors.
Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy
Authors: Mandel-Brehm Caleigh , Vazquez Sara E. , Liverman Christopher , Cheng Mickie , Quandt Zoe , Kung Andrew F. , Parent Audrey , Miao Brenda , Disse Emmanuel , Cugnet-Anceau Christine , Dalle Stéphane , Orlova Elizaveta , Frolova Elena , Alba Diana , Michels Aaron , Oftedal Bergithe E. , Lionakis Michail S. , Husebye Eystein S. , Agarwal Anil K. , Li Xilong , Zhu Chengsong , Li Quan , Oral Elif , Brown Rebecca , Anderson Mark S. , Garg Abhimanyu , DeRisi Joseph L.
Published: June 2022

Acquired lipodystrophy is often characterized as an idiopathic subtype of lipodystrophy. Despite suspicion of an immune-mediated pathology, biomarkers such as autoantibodies are generally lacking. Here, we used an unbiased proteome-wide screening approach to identify autoantibodies to the adipocyte-specific lipid droplet protein perilipin 1 (PLIN1) in a murine model of autoimmune polyendocrine syndrome type 1 (APS1). We then tested for PLIN1 autoantibodies in human subjects with acquired lipodystrophy with two independent severe breaks in immune tolerance (including APS1) along with control subjects using a specific radioligand binding assay and indirect immunofluorescence on fat tissue. We identified autoantibodies to PLIN1 in these two cases, including the first reported case of APS1 with acquired lipodystrophy and a second patient who acquired lipodystrophy as an immune-related adverse event following cancer immunotherapy. Lastly, we also found PLIN1 autoantibodies to be specifically enriched in a subset of patients with acquired generalized lipodystrophy (17 of 46 [37%]), particularly those with panniculitis and other features of autoimmunity. These data lend additional support to new literature that suggests that PLIN1 autoantibodies represent a marker of acquired autoimmune lipodystrophies and further link them to a break in immune tolerance.
Maternal Dietary Glycemic Index and Glycemic Load in Pregnancy and Offspring Cord Blood DNA Methylation
Authors: Küpers Leanne K. , Fernández-Barrés Sílvia , Mancano Giulia , Johnson Laura , Ott Raffael , Vioque Jesus , Colombo Marco , Landgraf Kathrin , Tobi Elmar W. , Körner Antje , Gaillard Romy , de Vries Jeanne H.M. , Jaddoe Vincent W.V. , Vrijheid Martine , Sharp Gemma C. , Felix Janine F.
Published: June 2022

OBJECTIVE

Suboptimal nutrition in pregnancy is associated with worse offspring cardiometabolic health. DNA methylation may be an underlying mechanism. We meta-analyzed epigenome-wide association studies (EWAS) of maternal dietary glycemic index and load with cord blood DNA methylation.

RESEARCH DESIGN AND METHODS

We calculated maternal glycemic index and load from food frequency questionnaires and ran EWAS on cord blood DNA methylation in 2,003 mother-offspring pairs from three cohorts. Analyses were additionally stratified by maternal BMI categories. We looked-up the findings in EWAS of maternal glycemic traits and BMI as well as in EWAS of birth weight and child BMI. We examined associations with gene expression in child blood in the online Human Early Life Exposome eQTM catalog and in 223 adipose tissue samples.

RESULTS

Maternal glycemic index and load were associated with cord blood DNA methylation at 41 cytosine-phosphate-guanine sites (CpGs, P < 1.17 × 10−7), mostly in mothers with overweight/obesity. We did not observe overlap with CpGs associated with maternal glycemic traits, BMI, or child birth weight or BMI. Only DNA methylation at cg24458009 and cg23347399 was associated with expression of PCED1B and PCDHG, respectively, in child blood, and DNA methylation at cg27193519 was associated with expression of TFAP4, ZNF500, PPL, and ANKS3 in child subcutaneous adipose tissue.

CONCLUSIONS

We observed multiple associations of maternal glycemic index and load during pregnancy with cord blood DNA methylation, mostly in mothers with overweight/obesity; some of these CpGs were associated with gene expression. Additional studies are required to further explore functionality, uncover causality, and study pathways to offspring health.
Autoantibodies to Perilipin-1 define a subset of acquired generalized lipodystrophy
Authors: Mandel-Brehm Caleigh , Vazquez Sara E. , Liverman Christopher , Cheng Mickie , Quandt Zoe , Kung Andrew F. , Parent Audrey , Miao Brenda , Disse Emmanuel , Cugnet-Anceau Christine , Dalle Stéphane , Orlova Elizaveta , Frolova Elena , Alba Diana , Michels Aaron , Oftedal Bergithe E. , Lionakis Michail S. , Husebye Eystein S. , Agarwal Anil K. , Li Xilong , Zhu Chengsong , Li Quan , Oral Elif , Brown Rebecca , Anderson Mark S. , Garg Abhinmanyu , DeRisi Joseph L.
Published: June 2022

  

Acquired lipodystrophy is often characterized as an idiopathic subtype of lipodystrophy. Despite suspicion of an immune-mediated pathology, biomarkers such as autoantibodies are generally lacking. Here, we used an unbiased proteome-wide screening approach to identify autoantibodies to the adipocyte-specific lipid droplet protein Perilipin-1 (PLIN1) in a murine model of Autoimmune Polyendocrine Syndrome 1 (APS1). We then tested for PLIN1 autoantibodies in human subjects with acquired lipodystrophy with two independent severe breaks in immune tolerance (including APS1) along with controls using a specific Radioligand Binding Assay and indirect immunofluorescence on fat tissue. We identified autoantibodies to PLIN1 in these two cases, including the first reported case of APS1 with acquired lipodystrophy and a second patient who acquired lipodystrophy as an immune-related adverse event following cancer immunotherapy. Lastly, we also found PLIN1 autoantibodies to be specifically enriched in a subset of patients with acquired generalized lipodystrophy (17/46; 37%) particularly those with panniculitis and other features of autoimmunity. These data lend additional support to new literature that suggests that PLIN1 autoantibodies represent a marker of acquired autoimmune lipodystrophies and further link them to a break in immune tolerance.
Estrategias para el fomento de las vocaciones científicas a partir de la covid-19 en los jóvenes de educación superior en Yucatán, México
Authors: González Herrera Karina Concepción
Published: June 2022

La problemática aquí abordada se asocia a la falta de una orientación temprana de las vocaciones científicas que promueva la continuidad educativa en los jóvenes. El objeto del presente trabajo fue determinar estrategias para el fomento de las vocaciones científicas en los jóvenes de educación superior de Yucatán, México, mediante acciones de difusión y divulgación durante la virtualidad provocada por la covid-19. El método de investigación fue por etapa y sistemática. En cada etapa se utilizó el enfoque de investigación cuantitativo. Se contó con muestras de 93.0 % y 97.0 % de confianza y un error de estimación del 0.07 y 0.03 para las etapas uno y dos, respectivamente. Los resultados en la primera etapa permitieron caracterizar a los jóvenes de 15 a 29 años sujetos de estudio. En la segunda etapa se plantean las estrategias para el fomento de las vocaciones científicas y una clasificación de acuerdo con su aplicación. En las conclusiones se pueden vislumbrar las áreas de oportunidad, la escasa búsqueda de información en bases de datos académicas, así como la ausencia de una cultura institucional centrada en la ciencia e investigación.
MODERNISMO, REGIONALISMO E O LUGAR DO FUTEBOL NA FICÇÃO DE JOSÉ LINS DO REGO
Authors: Buarque de Hollanda Bernardo Borges
Published: June 2022

O artigo inscreve a temática do futebol na história mais ampla do modernismo brasileiro, ao focar a trajetória do escritor regionalista José Lins do Rego no Rio de Janeiro dos anos 1940, quando se consagrou como romancista e, em paralelo, investiu na colaboração em jornais, por meio de uma série de crônicas esportivas. O recorte aqui proposto centra-se em um romance menos conhecido do autor, Água-mãe, e sustenta que o imaginário nacional-popular em torno da prática futebolística no país dá ensejo à inserção do assunto na ficção brasileira. Ao mesmo tempo, tal inscrição romanesca permite a renovação ficcional e a reelaboração da própria imagem do escritor, até então marcado pela paisagem regional nordestina, procurando refutar parcela da crítica literária, que o limitava à monotemática do memorialismo de sua região natal. Ao final da descrição e da análise do livro, o artigo conclui com o argumento de que a investida de José Lins do Rego em uma narrativa fictícia em torno do cenário urbano carioca e do interior fluminense, com o recurso a temas contemporâneos e ao cotidiano de então, como o futebol, mostra sua contribuição a propósitos gerais do ideário modernista, que se desdobrou e se metamorfoseou ao longo da primeira metade do século XX em distintos grupos, em diferentes correntes e em uma miríade de concepções artístico-literárias.
Pengaruh Laju Penambahan Doping Fosfor terhadap Struktur Kristal dan Luas Permukaan Spesifik Nanotitania dengan Metode Sol Gel
Authors: Nurhidayah Vidi , Manurung Posman , Ginting Ediman
Published: June 2022

Research on the effect of the addition phosphorus doping using a syringe pump with the sol-gel method. The purpose of this study was to determine the effect of the addition rate of phosphorus doping to the crystal structure and specific surface area of TiO2. Doping increment rate used are 0,4; 0,2; 0,13 and 0,1 ml/hours of TiO2 samples were calcined at 450ºC for 5 hours. The powder was characterized by x-ray diffraction (XRD) and surface area analyzer (SAA) by the BET method. XRD diffractogram generally shows that the nanotitania crystal structure phase is anatase which is the result of TTIP synthesis as the main source of TiO2. Particle size analysis using XRD data on TiO2 with different rates in a row that is 10.13; 9.98; 9.25 and 10.33 nm. BET test results for each sample were 86.954; 87,367; 99,694; 96,295 and 96,187 m2/g. The results of XRD characterization can affect the surface area, getting smaller the particle size, the greater surface area will be obtained.
Karakteristik Struktur Dan Fungsional Aspal Komposit dengan Perbandingan 85%:15%
Authors: Putra Samuel Nugroho , Sembiring Simon , Riyanto Agus
Published: June 2022

Synthesis and characterization of rice husk and asphalt silica composites was carried out with a ratio of 85%: 15%. Silica synthesis from rice husk was carried out by the sol-gel method. The materials used in this study were rice husks, asphalt, distilled water, gasoline, NaOH and HNO3. Then the silica and asphalt according to the comparison is set at 110oC. This study aims to look at the structural characteristics, functionality and physical properties, namely water content and thickness development of the sample. Based on the research that has been done, it can be concluded that from the results of XRD characterization the samples have silica and amorphous carbon structures, then based on FTIR characterization shows the -OH (hydroxil) functional groups occur at wave number 3524 cm-1, the hydroxide metal Si-OH (silanol) is oxidized into Si - O - Si and Si - O are formed at wave numbers 1084 cm-1, 810 cm-1 and 462 cm-1 and the formation of the C-H and C=O function group occurs at wave numbers 2923 cm-1 and 2361 cm-1. Then test the physical properties of the water content of 7.642% with a change in thickness development of 4.783%.
Sintesis Nanotitania dengan Cara Hidrotermal sebagai Fungsi Suhu
Authors: Sumiyati Sumiyati , Manurung Posman , Suprihatin Suprihatin
Published: June 2022

Research has been carried out on the synthesis of nanotitania by hydrothermal as a function of temperature. The purpose of this study was to determine the effect of temperature on the phase formation, structure and particle size of TiO2 using the hydrothermal method with TiOSO4 as the main ingredient. In this study, using temperature variations of 150, 200, 250 and 300°C and samples were characterized using X-Ray Diffraction (XRD) and Scanning Electron Microscopy (SEM). The phases formed are the anatase and rutile phases which have a tetragonal structure and the hilly phase with an orthorhombic structure. The rutile phase appeared predominantly in each sample and the sulfuric phase only appeared at 250ºC. The anatase phase obtains a particle size of 10-18 nm, where the higher the temperature, the bigger the particle size. Furthermore, the rutile phase obtained a particle size of 14-25 nm, where the higher the temperature, the smaller the particle size.
SIKAP DAN KEPUASAN KONSUMEN TERHADAP PRODUK OTAK-OTAK IKAN TENGGIRI DI KECAMATAN KOTAAGUNG KABUPATENTANGGAMUS (Kasus pada Otak-otak ikan tenggiri Ci Awa)
Authors: Awaliyah Hikmah , Sayekti Wuryaningsih Dwi , Endaryanto Teguh
Published: June 2022

The research aims to analyze the characteristics, attitudes and satisfaction of customers on mackerel fish“otak-otak”, as well as the relationship between consumer attitudes and consumercharacteristics. This study uses a survey method. The research location was home industry Ci Awa Kotaagung District of Tanggamus Regency. The determination of the location is done deliberately with the consideration that Kotaagung District is the largest fish-producing center and there are many fish-based home industries.  Respondents were 54 customers. The results of thestudy showed that consumers of Ci Awa are mostly female, age group of 17-35,high school graduates, self-employed workers, and the amount of income per month belongs to the moderate income group. Consumer attitudes towards Ci Awa's were positive. The levelof satisfaction of  customers of Ci Awa was in the satisfied category. Consumer characteristics (age,income, and education) have a relationship with the attitude of consumers of Ci Awa.Key words: attitudes, consumer, home industry.
DETERMINAN PRODUKSI AYAM BROILER DI KOTA KUALA PEMBUANG KABUPATEN SERUYAN
Authors: Winarti Lili , Permadi Rokhman
Published: June 2022

Our sub-sector is the sector that not only plays a role as a producer of meat for the community, but also has an important role in the development of the agricultural sector in general and in the development of livestock. Increasing population and production does not always represent a large profit or income for businesses. In broiler farming, there are several factors that are often faced by breeders, including broiler breeders in Kuala Pembuang City, Seruyan Regency. Uncertain availability and fluctuations in the price of production factors are serious problems that are always faced by farmers. The purpose of this study was to analyze the determinants of broiler production in Kuala Pembuang. This research was carried out from February to July 2021, starting from preparation, data analysis to report preparation. In this study, the population was broiler breeders in the city of Kuala Pembuang, especially in Seruyan Hilir and Seruyan Hilir Timur subdistricts, which collected 27 broiler breeders who were actively running a business. Data collection technique uses the census method and data processing uses linear regression analysis method with the help of Eviews 7 software. Based on the research, it was obtained: The significant determinants of broiler chicken production in Kuala Pembuang City were DOC and cages, where the DOC had a positive effect on production, while the cage had a negative effect on broiler production, and the insignificant determinants on broiler chicken production were feed, medicines, and labor use (TKDK and TKLK).Key words: Broiler Chicken, Determinants, Production.
FAKTOR-FAKTOR YANG MEMENGARUHI EKSPOR DAN PROSPEK EKSPOR PISANG PROVINSI LAMPUNG
Authors: Prasasta Sirilus Gatya , Ismono Raden Hanung , Situmorang Suriaty
Published: June 2022

This study aims to determine the factors that influence the exports volume of Lampung Province’s bananas and predict the exports of Lampung Province’s bananas.  This research based on the exports of some kind of banana produced by firm and by the corporation program involving the firm and smallholder farmers.  This study used both descriptive and quantitative analysis methods and data werw obtained from the relevant authorities as secondary data for 5 years, starting from the first quarter of 2015 to the first quarter of 2020.  The data were analyzed by regress time series data using Ordinary Least Square Method (OLS) and Autoregressive Integreted Moving Average (ARIMA).  The results of this study showed that the factors that significantly affect the exports volume of Lampung Province’s bananas are domestic banana production and the average of domestic banana price index.  The trend of banana exports prospect until the end of 2024 decreases. Key words: banana, exports prospect, Lampung, factor
Optimization of titanium cranial implant designs using generalized reduced gradient method, analysis of finite elements, and artificial neural networks
Authors: Martínez-Valencia M. , Navarro C. , Vázquez-López J. , Hernández-Arellano J. , Jiménez-García J. , Díaz-León J.
Published: June 2022

When cranial bone needs to be removed or lost, subsequent reconstruction of the defect is necessary to protect the underlying brain, correct aesthetic deformities, or both. Cranioplasty surgical procedures are performed to correct the skull defects requiring reconstruction of form and function. Personalized cranial implants can repair severe injuries to the skull can be done through This study presents the optimization of cranial titanium implants. A total of sixty different models were subjected to a simulation by Finite Element Analysis (FEA) applying the mechanical properties of a grade 5 titanium alloy (Ti6Al4V) implant material. The material was subjected to intracranial pressure (ICP) conditions, with a typical range (10 mm Hg) and twelve fixation points in the boundary conditions. An artificial neural network (ANN) was created to connect the designs, obtaining maximum displacements. Optimal designs were obtained using a generalized reduced gradient that minimizes the amount of material, maintaining as a restriction a maximum displacement of 0.1 mm for the 5th to 95th percentiles, which represent the group of individuals under study.
Implementasi Program Keluarga Harapan (PKH) di Nagari Kapeh Panji Jaya Talok pada Masa Pandemi Covid-19
Authors: Ummi Kalsum  , Mubarak Adil
Published: June 2022

This study aims to determine the implementation of the Family Hope Program (PKH) in Nagari Kapeh Panji Jaya Talaok during the Covid-19 Pandemic. This research was carried out using a qualitative descriptive approach in which data collection was based on the factors that became the main supporters of the research object. In this study, the withdrawal of informants was based on a purposive sampling technique which was based on the main criteria, namely the people of Nagari Kapeh Panji Jaya Talaok. This data collection is done by means of interviews, observation and documentation. Data analysis is done by collecting data, reducing data, presenting data, and drawing conclusions. Then the validity of this data was tested by triangulation of sources which was then analyzed. Based on the findings, it can be concluded that the Implementation of the Family Hope Program during the Covid-19 pandemic in Kapeh Panji Jaya Talaok can be said to be going well and the socialization carried out is still not effective because there are still people from the community who do not know the amount of assistance received, what It's just a requirement to become a KPM, and there are still people who abuse this assistance
Efektivitas Pelayanan Saat Pandemi Covid-19 di Dinas Kependudukan dan Pencatatan Sipil Kabupaten Lima Puluh Kota
Authors: Amelia Nikita
Published: June 2022

Effectiveness is the relationship between output and goals or objectives to be achieved. The definition of effectiveness is basically related to the achievement of policy goals or targets. Operational activities are said to be effective if the process of these activities achieves the final policy goals and objectives (spending wisely) Mahsun added that effectiveness is a measure of the success or failure of an organization to achieve its goals. If an organization succeeds in achieving its goals, then the organization is said to have been running effectively (Mahsun 2006: 182). Effectiveness is assessed using 8 indicators according to P. Siagian, namely, the first is the clarity of the goals to be achieved, the second is the clarity of the strategy for achieving the goals, the third is the analysis and formulation of a solid policy, the fourth is careful planning, the fifth is the preparation of the right program, the sixth is namely the availability of work facilities and infrastructure, Seventh, namely effective and efficient implementation, Eighth, namely an educational supervision and control system. Mahsun added that effectiveness is a measure of the success or failure of an organization to achieve its goals. If an organization succeeds in achieving its goals, then the organization is said to have been running effectively
Implementasi Program Nagari Swakelola Jaminan Kesehatan Nasioal (SWA-JKN) di Nagari Taram Kabupaten Lima Puluh Kota
Authors: Zettira Nindy , Malau Hasbullah
Published: June 2022

Nagari Taram Regulation Number 9 of 2019 concerning Taram Community Health Insurance is a reference in the implementation of the Nagari Swa-JKN Program. This program is given to poor independent communities (PBPU). In its implementation, the Nagari Swa-JKN Program has not been running effectively. This study aims to find the inhibiting factors in the implementation of the Nagari Swa-JKN Program. This study uses a qualitative descriptive research method. This research was conducted in Nagari Taram, Harau District, Lima Puluh Kota Regency. The results of this study indicate that the inhibiting factors in the implementation of the Nagari Swa-JKN Program, Harau District, Lima Puluh Kota Regency, namely (a) human resources of Pelita volunteers who are not qualified (b) no funding sources for Pelita volunteers (c) no supporting infrastructure for Pelita volunteers, (d) the low level of education and public understanding of health insurance, and (e) the decline in community economic activities due to the COVID-19 pandemic.
Investigating the Legal Discourse of Bill Clinton’s Impeachment Trial
Authors: Nasser Aldosari Bader
Published: June 2022

This paper presents a legal discourse analysis of Bill Clinton’s impeachment trial held in 1998. The paper’s main objective is to explore the different meanings communicated by the dexterous use of some lexical and pragmatic strategies used by discourse interlocutors involved in the trial. More specifically, the article offers a linguistic study of the testimony and statements of President Bill Clinton relating to his impeachment trial. The paper focuses on three main analytical dimensions: word selection, power relations, and questioning and answering, and the way these strategies influence the discourse participants’ conversational performance in the selected trial. To this end, this study draws on a legal discourse analysis approach as discussed by Coulthard (2013) and Mey (2016), focusing on lexicalization, the notion of power, and the use of questions and answers in courtroom settings. The overarching research question is: What are the different ideological and pragmatic meanings targeted beyond the use of selected words during the trial? Results reveal that language is a powerful tool in courtroom testimonies as it helps to extract information, verify evidence, draw legal outcomes, and encode and/or decode the underpinning meanings of courtroom discourse participants. These, in turn, serve to support or defy evidence and ultimately lead to issue a legally just decision.
Factors Influencing Secondary English as a Second Language Teachers’ Intentions to Utilize Google Classroom for Instructions during the Covid-19 Pandemic
Authors: Haniff Mohd Tahir Mohd
Published: June 2022

Google Classroom (GC) is a technical innovation that allows English as a Second Language (ESL) teachers and students to meet remotely to create a more engaging teaching and learning experience. This study investigated factors influencing ESL teachers’ intentions to utilize GC for instructions during the Covid-19 pandemic. An exploratory sequential technique was implemented as part of a mixed-methods research design. Eleven prior studies on educators’ views toward the use of GC were evaluated for the qualitative data analysis. The data from these investigations were analysed and categorized into topics and categories. The findings revealed that ESL teachers had a positive attitude toward utilizing GC with their pupils. For the quantitative data analysis, a research survey was performed. Technical support, attitude, perceived ease of use, perceived usefulness, and technological knowledge were studied as factors that impacted ESL teachers’ intentions to use GC. The sample includes 216 government secondary schools in the Kinta Selatan District of Perak. The outcomes of the study revealed that attitude, perceived usefulness, and technological knowledge all influenced the desire to use GC. The link between technical support and perceived ease of use, as well as the desire to use GC, was found to be negative. In linking the factors that determine GC intention, future research might incorporate a variety of moderating variables. The study’s findings might assist educators to understand the challenges of online learning in Malaysian education, as well as how to overcome them.
An Exploration of Voice in the Writing of Arab Learners of English as a Second Language
Authors: Alshehri Asmaa , Alasmari Muhammad , Qasem Fawaz , Ahmed Rashad
Published: June 2022

Developing a writer’s voicea challenging task for second-language writers who are new not only to the culture but also to the values associated with the target language. This study aims at exploring the writer’s voice of Arabic-speaking learners who study English as a Second Language. The study mainly discusses the following question: Do L2 learners who learn to write in both first and second language have an individual, collective, or depersonalized voice? Investigating the impact of culture and society on language and identity will facilitate the discovery of voice in second language writing. Methodologically, the study employs a qualitative research design in which data are collected via a discourse analysis of written texts. The analysis of the data adopted the holistic and dynamic perspective (Zhang & Zhan, 2020) by examining the various factors affecting Arabic-speaking learners of ESL including cultural factors, linguistic resources, and educational/academic pedagogy. Moreover, the study followed the analysis of the writer’s voice proposed by Lehman (2018) and used further Lehman and Anderson’s study of voice in academic writing (Lehman & Anderson, 2021). Lehman proposed three main topics to classify the writer’s voice: (a) individual, (b) collective, and (c) depersonalized. The findings of this research showed that approximately 55.96% of the voice of Arab learners of ESL fell in the individual category, 29.97% fell in the collective category, and 14.07% fell in the depersonalized category.
Deception Strategies in the Discourse of American Think Tanks: An Argumentative- Pragmatic Analysis
Authors: Al-juboori Ali , S. Mustafa Sabah
Published: June 2022

Deception is a misrepresentation of reality that attracted many researchers examining it from various perspectives. However, no due attention has been given to the discursive deception strategies in the work of think tanks. This study aims at exposing the deception strategies deployed in the conservative American think tanks’ discourse which concern itself with the (re)production of socio-political realities. The study holds the significance of the detection and explication of argumentative and pragmatic discursive deception strategies which impose ideological hegemony and socio-political polarization of the positively presented Self against the negatively presented Other. This study attempts to answer a twofold question: what are the discursive deception strategies involved in the work of think tanks, and why/how these strategies are applied? To this end, eight political texts from three think tanks were analyzed adopting an eclectic model based on van Dijk (2000) and Yule (1996). The analyzed data mainly focuses on four political themes namely (1) terrorism in Islam, (2) Russian role in the Middle East, (3) the Israeli-Palestinian conflict, (4) the U.S. policy in the Middle East. The results demonstrate the pervasiveness of discursive deception strategies in the think tanks’ discourse which endeavor to communicate an ideological polarization of a positive presentation of the Self against a negative presentation of the Other and reinforce a hegemony of particular socio-political realities. Findings can be beneficial for students of (critical) discourse analysis, media, communications studies, and English for special purposes
The Integral Iterative Method for Approximate Solution of Newell-Whitehead-Segel Equation
Authors:   Universiti Teknologi MARA, bin Selamat Mat Salim , binti Khusairi Nur’atikah , binti Abdul Gaffar Nurul Izzaty , binti Syed Huzaini Siti Nur Syafiqah
Published: June 2022

In this paper, the Newell-Whitehead-Segel (NWS) equation is solved using the integral iterative method (IIM) to determine the accuracy and effectiveness of the method. Comparison of results obtained by IIM with the exact solution and other existing results obtained by other methods such as new iterative method (NIM), Adomian decomposition method (ADM) and Laplace Adomian decomposition method (LADM) revealed the accuracy and effectiveness of the method. The approximation results obtained by IIM is comparable with the others. IIM is reliable and easier in solving the nonlinear problems since this method is simple, straightforward and does not require calculating multiple integral and demand less computational work.
PENGENALAN PEMANFAATAN RUMPUT MULATO DAN TEKNOLOGI PENGAWETANNYA SEBAGAI UPAYA PENINGKATAN PRODUKTIVITAS TERNAK RUMINANSIA
Authors: Mayasari Novi , Salman Lia Budimulyati , Susilawati Iin , Ismiraj Muhammad Rifqi
Published: June 2022

Terdapat beberapa masalah yang terjadi di dalam penyediaan hijauan pakan untuk ternak ruminansia, salah satunya adalah jumlah produksinya yang cenderung fluktuatif. Penyediaan dan pemberian pakan dalam usaha peternakan merupakan permasalahan utama yang perlu mendapat perhatian. Kuantitas, kualitas, dan kontinuitas hijauan merupakan faktor penting dalam menentukan produktivitas ternak ruminansia. Salah satu hijauan pakan ternak yang memiliki nilai mutu baik dan mampu menyediakan kebutuhan ternak adalah rumput mulato. Hal ini dapat dilihat dari beberapa aspek tertentu yaitu di antaranya kemampuan hidup pada musim kemarau, mudah dikembangbiakkan melalui anakan dan memiliki jumlah produksi serta palatabilitas yang cukup tinggi. Informasi ini dirasa perlu untuk diberi tahukan kepada para peternak. Terdapat enam entitas kelompok peternak dan perusahaan peternakan yang berlokasi di Jawa Barat dan D. I. Yogyakarta yang dijadikan objek dalam kegiatan pengabdian kepada masyarakat ini. Kegiatan ini dilaksanakan dengan metode daring menggunakan platform Zoom Meeting, yang terdiri atas ceramah dan diskusi. Hasil dari kegiatan ini tercermin pada respons post-test terhadap pemahaman peserta mengenai topik yang diberikan, yang hasilnya terdapat peningkatan pemahaman peserta berkisar pada 50% dibandingkan dengan sebelum kegiatan ini dilaksanakan.
PEMBUATAN MINUMAN ISOTONIK DAN SUSU COKLAT SEBAGAI OLAHAN BUAH KELAPA DI DESA BALE KECAMATAN TANANTOVEA Jaya Hardi, Ruslan, Abd. Rahman Razak dan Ahmad Ridhay
Authors: Hardi Jaya , Ruslan Ruslan , Razak Abd. Rahman , Ridhay Ahmad
Published: June 2022

Desa Bale merupakan salah satu daerah yang terletak di Kabupaten Donggala, Sulawesi Tengah. Penduduk di Desa Bale umumnya sebagai petani kelapa. Pembuatan produk olahan kelapa yang inovatif masih sangat kurang di Desa Bale. Minuman isotonik dan susu coklat santan kelapa dapat menjadi produk olahan baru bagi masyarakat setempat. Tujuan kegiatan ini adalah untuk menambah keterampilan masyarakat di desa Bale dalam mengolah air kelapa tua dan santan kelapa menjadi produk yang menarik dan memiliki nilai jual yang menjanjikan. Metode yang digunakan pada kegiatan ini adalah penyuluhan yang diikuti dengan demonstrasi. Hasil dari kegiatan yang dilakukan adalah keterampilan masyarakat mitra di desa Bale bertambah dalam membuat minuman isotonik dan susu coklat santan kelapa dengan menggunakan metode yang sederhana dan murah. Hasil pengukuran tingkat kepuasan menunjukkan bahwa 80% peserta atau mitra sangat puas terhadap pelaksanaan kegiatan pengabdian. Masyarakat mitra siap untuk mengembangkan produk olahan hasil pelatihan dalam bentuk produk yang siap dipasarkan.
Clinical Characteristics and Outcomes of Pregnant Women Confirmed with SARS-COV-2 Admitted in the Hospitals in Baghdad
Authors:   Associate Professor, Consultant Family Physician, Family and Community Medicine Department, Alkindy College of Medicine, University of Baghdad, Iraq., Al-Khazrajy Lujain Anwar
Published: June 2022

Background: Pregnant women are considered one of the most vulnerable groups for COVID-19. Routine but essential services are the most affected during emergencies, therefore practitioners must pay closer attention to women and newborns to minimise the impact of the pandemic on these vulnerable populations.Objectives: To describe clinical characteristics and outcomes of pregnant women admitted to hospitals with SARS-CoV-2 in Baghdad during 2020.Methods: Across-sectional retrospective study was conducted in six maternity hospitals in Baghdad during a period of ten months, including 170 pregnant ladies who came to the hospital for labour or management of health problems related to pregnancy and testedpositive for COVID-19. The data were collected from medical records and patient medical sheets of admitted ladies, phone calls, and questionnaires.Results: The mean age of the included women was 29.59±6.78 years, and 50.6% of patients were aged less than 30 years with 41.2% having primary education level. 78.2% of patients were housewives, 94.7% of pregnant women had a single foetus, 84.7% delivered by caesarean section, 58.2% reported fever as the most common symptom, and 43.5% of neonates of mothers with COVID-19 had a negative test result of COVID-19.Conclusion: The majority of pregnant ladies were symptomatic and hypertension was the most common co-morbidity in the included pregnant ladies. There was a significant association between age and the presence of symptoms of COVID-19 infection in which patients aged less than thirty years who presented with symptoms, especially fever and dyspnoea were more than patients aged thirty years old or more.
Climate Change Projections and its Impacts on Potential Malaria Transmission Dynamics in Uttarakhand
Authors:   Qatar Meteorology Department, Civil Aviation Authority, Doha, Qatar., Bal Prasanta Kumar
Published: June 2022

Introduction: Mountainous regions in India are prone to malaria disease but with low intensity. In this context, Uttarakhand state, a hilly region situated in the northern parts of India and located in the central Himalayan region is also prone to malaria disease and malaria is present in four out of its 13 districts which are mainly plain stations.Method: A numerical dynamical malaria model, VECTRI is used in this study based on various climatic and non-climatic parameters such as surface mean temperature, rainfall, population density etc. to predict the future malaria transmission dynamics in Uttarakhand state. VECTRI model is simulated with the inputs obtained from the CCSM4 global climate model for the baseline period (1975-2005) and for the near future projection period 2006-2035 (hereafter referred to as 2030s). Rainfall, surface mean temperature, mosquito vector density and entomological inoculation rate (EIR) during the Indian monsoon season (June-Sept) are being investigated from the outputs of VECTRI model simulations to predict the future malaria transmission dynamics in the Uttarakhand region with respect to the future climate change under RCP 8.5 emission scenario. Results: Results indicate an overall increase in EIR values (increase is around 30%), indicating an increase in future malaria transmission in Uttarakhand state as a whole with a maximum increase in the central parts of the state which are plain areas with a warming temperature of 1°C and with an increase in rainfall of 15% by 2030s with respect to the baseline period.Conclusion: Future warming and increase in the rainfall intensity during the summer monsoon season (June-September) over Uttarakhand state could potentially increase the spatial and temporal distribution of malaria transmission over the regionin future under RCP8.5 scenarios.
A Study of Malaria in India
Authors:   Scientist ‘E’, National Institute of Malaria Research, Dwarka, New Delhi, India., Nath Arvind
Published: June 2022

The Annual Parasite Incidence (API) of malaria for India during 2018 was 0.32 which came down to 0.14 during 2020. If interventions like the treatment of asymptomatic carriers take place, it is expected that the API will come down further, not only in the states and union territories, but at the national level as well.
Neonatal Morbidity and Mortality Pattern in a Mission Hospital in Nigeria: A Facility-Based One Year Retrospective Study
Authors:   Department of Clinical Nursing, University College Hospital, Ibadan, Nigeria., IKE Elizabeth Urenna
Published: June 2022

Neonatal period is sensitive due to the physiological adaptations newborns make to adapt to extra uterine environment. High percentage of mortality during infancy occur during this period especially in developing countries. Nigeria neonatal mortality record is among the worst in the world.This study examined morbidity and mortality pattern of neonates admitted to Our Lady of Apostles (OLA) Catholic hospital, Okeofa Ibadan. This hospital-based retrospective study was carried out among admitted neonates at OLA Catholic hospital Oluyoro Ibadan, for a period of 1 year from May, 2017 to June 2018. Overall, 360 complete case notes were reviewed. A 5-sectioned structured checklist containing 39 items designed by the researchers was used for data collection. Data was analyzed using descriptive statistics and chi-square test.Among 360 neonatal case notes that were studied, 310 (86.1%) were admitted within the first and 7th day of life with the mean day of admission being 4 ± 5.5 days. 248 (68.9%) of the neonates had normal birth weight, 59 (16.4%) had low birth weight and 53 (14.7%) were macrosomic babies with the mean weight being 3 ± 0.6 kg. The two main causes of admission were neonatal sepsis 113 (31.4%) and birth asphyxia 94 (26.1%).A total of 248 (68.9%) neonates survived and were discharged home, 79 (21.9%) were discharged against medical advice, 25 (6.9%) were referred to a higher centre and 8 (2.2%) died. There is a significant association between neonates’ gender (P0.025), birth weight (P0.013) and neonatal outcome.Sepsis and birth asphyxia were the leading causes of neonatal morbidity and mortality. Efforts should be intensified to improve the care provided to women and their newborns during labor and immediate postpartum period respectively.
Effects of a single dose of orally and rectally administered misoprostol in an in vivo endotoxemia model in healthy adult horses
Authors: Kimura Shune , McCoy Annette M. , Boothe Dawn M. , Wooldridge Anne A. , Graff Emily , Hammack Samantha M. , Cresci Lucia , Hofmeister Erik , Lascola Kara M.
Published: June 2022

OBJECTIVE

To describe misoprostol pharmacokinetics and anti-inflammatory efficacy when administered orally or per rectum in endotoxin-challenged horses.

ANIMALS

6 healthy geldings.

PROCEDURES

A randomized 3-treatment crossover design was performed with a minimum washout period of 28 days between treatment arms. Prior to endotoxin challenge (lipopolysaccharide, 30 ng/kg IV over 30 minutes), horses received misoprostol (5 µg/kg once) per os (M-PO) or per rectum (M-PR) or water as control (CON). Clinical parameters were evaluated and blood samples obtained to measure plasma misoprostol free acid concentration, leukocyte counts, and tumor necrosis factor-α (TNFα) and interleukin 6 (IL-6) leukocyte gene expression and serum concentrations.

RESULTS

In the M-PO treatment arm, maximum plasma concentration and area under the concentration-versus-time curve (mean ± SD) were higher (5,209 ± 3,487 pg/mL and 17,998,254 ± 13,194,420 h·pg/mL, respectively) and median (interquartile range) time to maximum concentration (25 min [18 to 34 min]) was longer than in the M-PR treatment arm (854 ± 855 pg/mL; 644,960 ± 558,866 h·pg/mL; 3 min [3 to 3.5 min]). Significant differences in clinical parameters, leukocyte counts, and TNFα or IL-6 gene expression or serum protein concentration were not detected. Downregulation of relative gene expression was appreciated for individual horses in the M-PO and M-PR treatment arms at select time points.

CLINICAL RELEVANCE

Considerable variability in measured parameters was detected among horses within and between treatment arms. Misoprostol absorption and systemic exposure after PO administration differed from previous reports in horses not administered LPS. Investigation of multidose administration of misoprostol is warranted to better evaluate efficacy as an anti-inflammatory therapeutic.