bluuebunny/crossref_metadata_2025 huggingface dataset:
Kinerja Pokdarwis dalam Upaya Pengembangan Ekowisata Melalui Program Dinas Kepemudaan, Olahraga, dan Pariwisata (Disporapar) Kabupaten Pringsewu
Authors:   Universitas Lampung, Anisa Muthidatul , Yulianto Yulianto ,   Universitas Lampung, Sulistyowati Rahayu ,   Universitas Lampung
Published: March 2022

Disahkannya UU Nomor 24 Tahun 2011 tentang Badan Penyelenggara Permasalahan yang terjadi dalam kepariwisataan Kabupaten Pringsewu adalah pengelolaan yang kurang baik pada destinasi ekowisata yang menyebabkan terjadinya penurunan kunjungan. Oleh karena itu diperlukanya peran DISPORAPAR (Dinas Kepemudaan, Olahraga, dan Pariwisata) untuk membantu mengembangkan wisata dan meningkatkan kinerja Pokdarwis. Peran pemerintah daerah dalam upaya pengembangan ekowisata didasarkan pada Pasal 6 dan Pasal 8 Undang-Undang Nomor 10 Tahun 2009. Metode penelitian yang digunakan dalam penelitian ini adalah metode penelitian deskriptif, dengan analisis data kualitatif. Metode penelitian yang digunakan dalam penelitian ini adalah metode penelitian deskriptif, dengan analisis data kualitatif. Hasil penelitian menunjukan bahwa, (1) Kinerja Pokdarwis dalam upaya pengembangan ekowisata melalui program Dinas Kepemudaan, Olahraga, Dan Pariwisata (DISPORAPAR) Kabupaten Pringsewu dapat dilihat dari tingkat pencapaian sasaran atau tujuan yang telah ditetapkan dengan memperhitungkan inputs, outputs, outcomes, benefit dan impact dari destinasi wisata Kabupaten Pringsewu. Hasil penilaian yang didapatkan dari unsur-unsur tersebut selanjutnya dapat dilihat dan diambil kesimpulan terkait kinerja Pokdarwis dalam melakukan pengembangan ekowisata melalui program DISPORAPAR dapat dikatakan belum optimal karena jika ditinjau dari berbagai aspek yang peneliti lakukan masih sangat banyak kekurangan. (2) Faktor penghambat kinerja Pokdarwis dalam upaya pengembangan ekowisata di Kabupaten Pringsewu adalah kurangnya kesadaran Pokdarwis, kurangnya dukungan permodalan, kurangnya komunikasi antar anggota, kurangnya peran pemerintah.
Partisipasi Masyarakat Dalam Program Kota Tanpa Kumuh (Kotaku) Untuk Mewujudkan Pembangunan Berkelanjutan
Authors:   Universitas Lampung, Simarmata Dewi Syintia , Tresiana Novita ,   Universitas Lampung, Hutagalung Simon Sumanjoyo ,   Universitas Lampung
Published: March 2022

Program Kota Tanpa Kumuh (KOTAKU) merupakan model pembangunan partisipatif dimana partisipasi masyarakat menjadi syarat mutlak dalam menjalankan program ini. Tujuan penelitian ini untuk melihat bentuk-bentuk partisipasi masyarakat dalam Program KOTAKU Untuk Mewujudkan Pembangunan Berkelanjutan di Kelurahan Sawah Brebes melalui tahapan pengambilan keputusan, pelaksanaan, pengambilan manfaat dan evaluasi. Tujuan lainnya untuk menganalisa faktor penghambat partisipasi masyarakat dalam mewujudkan pembangunan berkelanjutan. Penelitian ini dapat menjadi masukan bagi pemerintah daerah dalam upaya meningkatkan partisipasi masyarakat melalui kebijakan penanganan perumahan dan permukiman kumuh, serta memberikan perhatian khusus terhadap lingkungan kumuh masyarakat dalam hal penyediaan fasilitas pengelolaan limbah usaha
Koordinasi Antar Stakholder dalam Pengembangan Ekowisata Desa Sungai Langkah Kecamatan Gedong Tataan Kabupaten Pesawaran
Authors:   Universitas Lampung, Nuwita Maya Shafa
Published: March 2022

Pengembangan pariwisata tentunya dikaitan oleh peran peran stakeholder dalam pelaksanaan pengembangan wisatanya. Stakeholder adalah orang-orang atau kelompok yang secara langsung atau tidak langsung di pengaruhi oleh suatu hal. Adanya stakeholder tentu adanya alur koordinasi yang dijalan sebagai kunci kerjasama dalam pengembangan wisata. Artinya tanpa adanya koordinasi yang baik antar stakehorder maka pengembangan wisata tidak terarah dalam satu kesatuan tindakan. Koordinasi merupakan suatu usaha kerjasama antara badan, instansi, unit dalam pelaksnaan program dan berperan sangat vital sehingga terdapat saling mengisi, membantu dan melengkapi. Tipe penelitian yang digunakan dalam penelitian ini adalah tipe deskriptif dengan pendekatan kualitatif, teknik pengumpulan data, observasi, wawancara, dokumentasi. Hasil penelitian ini menunjukan bahwa Koordinasi yang dilakukan oleh para stakeholder dalam pengembangan objek wisata Desa Sungai Langka sudah berjalan dengan dinamis, yang ditandai dengan adanya perubahan dan kemajuan dalam pengelolaan pariwisata. Koordinasi yang dilakukan oleh para stakeholder tidak selalu melalui forum resmi atau rapat, melainkan melalui dialog-dialog non formal namun masih dalam tatanan koridor yang jelas. Adapun beberapa kendala yang dihadapi dalam koordinasi antar stakeholder seperti timbulnya pemikiran ego dari masing-masing pihak individu yang menomorsatukan kepentingan pribadi, kedua kendala yang disebabkan oleh minimnya anggaran dana yang membuat alurkomunikasi sedikit terhambat.
Improving students’ writing achievement in descriptive text using picture series through WhatsApp Messenger at SMPN 34 Bandar Lampung
Authors:   Universitas Lampung, Mahesa Cintia Chandra , Yufrizal Hery ,   Universitas Lampung, Burhanuddin Burhanuddin ,   Universitas Lampung
Published: March 2022

This quantitative research was conducted to investigate the use of picture series through WhatsApp could give positive impact on the students’ writing in descriptive text. The samples of this research were the second-grade students of SMPN 34 Bandar Lampung. The researcher used experimental group design which applied pretest and posttest as the instruments. Besides, there were two meetings as the treatment. The data were analyzed by using Repeated measure T-Test. The result showed that there was significant improvement on students’ writing after the implementation of picture series. The mean of the pretest was increased from 61.13 in the first test to 70.73 in the second test. Moreover, the gain of the test was quite high by having the number of 9.6. Then, the statistical calculation of the students’ score also showed that the t-table was higher than the t-table (10.298 > 2.052). The highest aspect that improved the most was organization. The mean for this aspect was increased from 14.12 (pretest) to 17.50 (posttest) with the score of the gain was 0.5762. Briefly, it could be concluded that the H1 is accepted and the H0 is rejected.
The Use Of Jigsaw Strategy To Improve Students' Reading Comprehension Achievement At SMKN 1 CANDIPURO
Authors:   Universitas Lampung, Alawiyah Tuti , Suparman Ujang ,   Universitas Lampung, Nisa Khairun ,   Universitas Lampung
Published: March 2022

The objectives of this research are to find out the improvement of the students' reading ability before and after the implementation of jigsaw strategy and also to identify student perception about the use of jigsaw strategy at SMK N 1 Candipuro. This research was a quantitative research and the method was one group pretest and post-test design. The reading test was administrated as the instrument in this research. In pre-test, students mean score was 53. 86 while in post-test it increases to 65.46; the gain obtained in pre-test to post-test is 11.59. The analysis of SPSS 20 shows that there is improvement of students' reading ability after the implementation of jigsaw strategy; Based on seeing the analysis of students' work in pre-test and post-test on each aspect of reading. It could be found that determining main idea was the aspect that increased the most. Keyword: Jigsaw strategy, Reading
The use of collaborative strategic reading to improve students’ reading comprehension.
Authors:   Universitas Lampung, Manjorang Porti Rosenna Br , Suparman Ujang ,   Universitas Lampung, Burhanuddin Burhanuddin ,   Universitas Lampung
Published: March 2022

The objectives of this research was to find out whether there was a statistically significant difference of students’ reading comprehension ability of narrative texts after the students were taught through CSR strategy and also to find out which aspect of reading comprehension improves the most after CSR was implemented in teaching reading at the tenth grade of SMKN 1 Terbanggi Besar . This research was a quantitative research and the method was one group pre-test and post-test design. In pre-test students mean score was 52.17 while in post-test it increase to 76.15; the gain obtained in pre-test to post-test was 23.98. The subjects of the research were 26 students at the tenth grade of SMKN 1 Terbanggi Besar . The reading comprehension test was used as the research instrument. The data were analyzed using paired sample t-test. The result showed that there was a statistically significant difference of students’ reading comprehension of narrative texts. Determining main idea was the aspect that improved the most after implementing Collaborative Strategic Reading technique.
Students' perception toward the use of google classroom as an assessment media in EFL
Authors:   Universitas Lampung, Rinanda Antika , Yufrizal Hery ,   Universitas Lampung, Deviyanti Rafista ,   Universitas Lampung
Published: March 2022

The objectives of this research were to identify the students’ perception of the use of online assessment on Google Classroom in EFL classrooms and to find out the students’ challenges in doing online assessment in Google Classroom in EFL classrooms. The subjects were consisted of 45 English department students of Lampung University. A close-ended and an open-ended questionnaire were used to collect the data. The data from close-ended questionnaire was analyzed by using descriptive statistic on SPSS, while the data from the open-ended questionnaire was analyzed manually. The result of this study indicated that the students have a positive perception toward the use of online assessment in Google Classroom. It happened because the mean score of the questionnaire was 3.67 to 5.00. the range score indicates that the level of students’ perception is on the high level. This study also found out that there are several challenges of the students faced when using online assessment in Google Classroom, those are; time, internet connection, the system problems and about the controller. Based on the research finding above, it be concluded that there are strengths and weaknesses toward the implementation o online assessment. Although as previously from the results of the data obtained that students have positive perceptions of the use of online assessment in Google Classroom, it does not mean that there are no difficulties from the students in doing the online assessment in Google Classroom. Keywords: Google Classroom, online assessment, students’ perception
Improving students' speaking skill through storytelling at the tenth grade of SMA Al-Kautsar Bandarlampung
Authors:   Universitas Lampung, Salsya Khairani Putri , Mahpul Mahpul ,   Universitas Lampung, Deviyanti Rafista ,   Universitas Lampung
Published: March 2022

The objectives of this research were to find out whether there is an improvement of the students’ skill in speaking English after being taught of storytelling technique and to find out the students’ perception toward the implementation of storytelling technique. The approach of the research was quantitative. The subjects were 30 students of class X IPS 2 at SMA Al-Kautsar Bandar Lampung in 2019/2020 academic year. The students’ speaking scores were compared between the pre-test and the post-test by using Paired Sample T-test with the significant level 0,000. The students’ perception toward the implementation of storytelling technique was 0.754. The result of the research showed that there was an improvement of the students’ speaking skill from the pre-test (56.73) to the post-test (68.25). Furthermore, the result of questionnaires showed that most students gave positive perception toward the implementation of storytelling technique in improving students’ speaking skill. This suggests that storytelling technique can be used as a strategy to improve the students’ speaking skill. Keywords: storytelling technique, speaking skill, students’ perception.
Applying Blended Learning through WhatsApp group chat to improve students’ achievement in writing analytical exposition text at SMA Negeri 1 Terbanggi Besar
Authors:   Universitas Lampung, Fadhillah Nurul , Raja Patuan ,   Universitas Lampung, Putrawan Gede Eka ,   Universitas Lampung
Published: March 2022

The objectives of this research were to find out whether there was any improvement on students’ analytical exposition text writing achievement, and their perceptions after the implementation of blended learning through WhatsApp group chat. This research was a quantitative research which was conducted through a one group pre-test and post-test design. The subjects of this research were thirty five students in SMA Negeri 1 Terbanggi Besar. The data were collected through pre- and post-tests in the forms of analytical exposition text and a questionnaire. The data were analyzed by using Paired Samples T-Test and descriptive statistics. The students’ writing achievement were compared between the pre and the post test. The result showed that there was statistically significant improvement of the students’ writing achievement after they were taught through blended learning by WhatsApp group chat. It could be seen from the computation of Paired Samples T-Test where the T-value (8.628) was higher than t-table (2.032) with the significance level of 0.00. Therefore, their perceptions toward blended learning through WhatsApp group chat in terms of five aspects of writing were also positive. Then this research proved that blended learning is effective to be implemented in developing and improving students’ writing achievement.
The impact of error correction strategies toward student’s anxiety in speaking
Authors:   Universitas Lampung, Saentika Abdina , Flora Flora ,   Universitas Lampung, Nisa Khairun ,   Universitas Lampung
Published: March 2022

This research aimed to find out (i) how the students’ anxiety in speaking after being corrected through teacher-correction strategy, and (ii) how the students’ anxiety after being corrected through peer-correction strategy. This study was a quantitative which used the one-shot case study design. Then, two sets of questionnaire were used as the research instruments. It was conducted in third grade of Senior High School 1 Belalau. The result shows that the students’ anxiety is lower after being corrected through teacher-correction strategy. Furthermore, the students anxiety is not lower after being corrected by peers. The findings suggested that The students preferred to be corrected more by the teachers than their peers.
A Study on Student’ Speaking Ability of Telling Historical Experience At MA Nurul Wathan Pelangiran
Authors: Arisandi Yogi , Natasha Harum
Published: March 2022

According to 2013 curriculum, the English learning goal is to develop the students’ potential to have the communicative competence in interpersonal, transactional, and functional in written and spoken form. However, according to the preliminary study at Islamic Senior High School Nurul Wathan Pelangiran, the students have difficulties in reaching the passing grades of English; 75. Another thing is teh students have difficultiesnin producing proper vocabularies and good pronunciation. They did not know the appropriate vocabularies while speaking and they often failed to pronounce some words properly. These problems appear to be in educational system where the students have learnt English speaking since the elementary school, but their ability to speak is still low. This research was aimed to find out the students’ speaking abillity of telling historical experience at tenth grade in English Classroom and to know the most dominant component of students’ speaking ability of telling experience at tenth grade of MA Nurul Wathan Pelangiran. This research is a descriptive quantitative research and in collecting the data, the instrument was speaking test. The sample was the total population from social class. The researchers found that the mean score of students’ speaking ability of telling historical experience is 52.50, and categorized as less level. The most dominant component of students’ speaking ability is vocabulary with mean score 2.86 or 57.2%. Students’ speaking is mostly  on less level. So the students need to prepare and practice more about speaking. They often pause their speaking during the test, or the students did find it difficult to deal with vocabularies related to historical experience.
A Descriptive Qualitative on Teachers’ Strategies in Teaching Listening Comprehension
Authors: Lukita Rina , Gushendra Rizky
Published: March 2022

The purpose of this research is to explore the implementation of teachers’ strategies in teaching listening comprehension. There are three English teachers of SMPN 1 Rimba Melintang, who have been selected by purposeful sampling as the participants. However, A descriptive qualitative research was designed to presume the three aspects of teachers’ strategies i.e. teachers’ interpretation of teaching strategies, whilst-teaching, and assessing students listening comprehension. In collecting data, the researchers conducted semi-structured interview in order to gain the deeper information from the participants. The results and analysis of the interviews found that the teachers’ interpretation of strategies were interdependent and interrelated with other skills, which means to decide a strategy is very influential for the learning outcome.  However, the decision of using different strategies might have different results.  The second aspect, the audio-visual media enable the students to hear sounds and notice directly to the intended object, which followed by a group discussion and quizzes for question-answer sessions, that the students response immediately and spontaneously. Finally, the teacher assesses the results of student work by any particular drills, such as, summarizing the materials, noticing main ideas of the talks, doing presentation, and questions and answers.
Students’ Involvement in EFL Online Classroom during the Covid-19 Pandemic Era
Authors: Syahputra Idham , Isnani Nur
Published: March 2022

According to Norziani Dahalan, (2012) students’ involvement is important in online classes. When students communicate verbally with teachers or with friends, their abilities will automatically develop. However, in online classes the researcher found that students were passive and didn't want to calculate their progress, they would be slower. Therefore, this study aims to see how the students’ involvement in EFL online classroom during Covid-19 Pandemic at State Senior High School 1 Bengkalis with the hope that teachers can try to overcome it. This type of research is descriptive qualitative research. To measure the data, researchers used observation, video documentation, and interviews. The data analysis technique used in this research is to use qualitative data analysis techniques developed by Miles, (2019) there are includes three activities, namely: data reduction, data presentation, concluding, or levers. The results of this study are: First, students’ involvement with the teacher is passive. Second, students’ involvement with other students. Students can interact with their classmates in the online learning process even though the response is very time-consuming because the teacher or student's internet connection network is sometimes bad and interferes with the learning process. Third, students’ involvement with the material. The involvement of English students with learning materials at SMA N 1 can be said to be good. Because the English teacher teaches well like how he does face-to-face learning in class. The difference is, teacher uses an online application.
Designing a Cost-Time-Quality-Efficient Grinding Process Using MODM Methods
Authors: Mahjoob Meysam , Abbasian Pouneh
Published: March 2022

In this paper, a multi-objective mathematical model is developed to optimize the grinding parameters Such as grinding time, cost, and related surface quality metrics such as workpiece speed, depth of cut and wheel speed. The mathematical model consists of three conflicting objective functions subject to wheel wear and production rate constraints. Exact methods cannot solve the NLP model in few seconds, therefore using Meta-heuristic algorithms that provide near-optimal solutions is not suitable. Considering this, five multi-objective decision-making (MODM) have been used to solve the multi-objective mathematical model using general algebraic modelling system (GAMS) software to achieve the optimal parameters of the grinding process. The MODM methods provide different effective solutions where the decision-maker (DM) can choose each solution in different situations. Different criteria have been considered to evaluate the performance of the five MODM methods. Also, a technique for order of preference by similarity to ideal solution (TOPSIS) has been used to obtain the priority of each method and determine which MODM method performs better considering all criteria simultaneously. The results indicated that the weighted sum method (WSM) and goal programming method (GP) are the best MODM methods, as both of them provide competitive solutions. In addition, these methods obtained solutions that have minimum grinding time, cost, and surface roughness among other MODM methods.
Efektivitas Penggunaan Busy Book Terhadap Kecerdasan Logika Matematika Anak Di Taman Kanak-Kanak
Authors: Sakri Alfaregi Ilham , Wirman Asdi
Published: March 2022

This study aims to find out how effective the use of busy book on the logical intelligence of early childhood mathematics. This study linked 28 children as the object of research, including 14 children from the experimental class and 14 children from the control class.  This type of research is quantitative with a quasi-experimental design, namely pre-test post-test control group.  The data collection technique in this study used an assessment instrument by giving a score based on the achievement of child development in accordance with the indicators on the research instrument.  Before carrying out the research, the instrument validity test was conducted, namely, joint testing with experts in the field of early childhood mathematics and testing of research instruments in order to obtain a valid and reliable instrument.  The research data analysis technique uses the normality test to determine whether the research data is normally distributed and the homogeneity test to test whether the data is homogeneous.  The next step is to measure whether there is a significant effect of using busy books on children's mathematical logical intelligence, then a hypothesis test and effect size test are carried out which obtain significant results of 0.003 which means significant or influential value, and the d value of effect size test is 1.23 which means it has an effect strong category
Pengaruh Penggunaan Media Video Terhadap Hasil Belajar Mata Pelajaran Ipa Pada Program Kesetaraan Paket B
Authors: Pratiwi Silfia , Syur'aini Syur'aini
Published: March 2022

The background of this research is the lack of activeness of students in learning science subjects in the Package B Equivalence Program because the media used by tutors does not vary. This results in low student learning outcomes. This study aims to describe student learning outcomes by applying video media to science subjects and to see the effect of applying video media to learning outcomes in the Package B Equivalence Program. The approach used in this research is a quantitative experimental type with a posttest-only control group model. . All students of the Package B Equivalence Program at PKBM Sentosa Hati class IX became the population in this study. The samples were taken using simple random sampling technique from class IXA and IXB. Researchers collect data using tests. Data analysis using t-test technique. The results of this study are: 1) the learning outcomes of students who do not use video media have a low average; 2) the learning outcomes of students who were given video media treatment had a high average; and 3) there is a significant effect between the use of video media on the learning outcomes of students' science subjects in the Package B Equivalence Program
STABILITY AND BIFURCATION ANALYSIS OF COVID-19 MATHEMATICAL MODEL INCORPORATING CASE DETECTION
Authors: Odetunde Opeyemi , Ibrahim Mohammed Olanrewaju , Olotu Olanrewaju Thomas , Uwaheren Ohigweren Airenoni , Akinyemi Samuel Tosin
Published: March 2022

COVID-19 became a household name globally in the year 2020 after it was first discovered in Wuhan, China in December 2019. It is a global pandemic that shut the economy of all nations in the larger part of year 2020 by forcing a compulsory holiday on mankind due to its threat of mass death. The menace of this pandemic was combated with the total arsenal in human capacity. One of such weapons is case detection that leads to either self-isolation or quarantine. This weapon helps to reduce the number of new cases that may arise from undetected asymptomatic/symptomatic carriers within a population. In this article, the dynamics of COVID-19 transmission were studied by developing a mathematical model incorporating case detection, the impact of sensitization, and role of early diagnosis in curbing the spread of this disease. The basic properties in terms of existence, uniqueness, and boundedness of solution for the formulated model were discussed. Also, the model was found to exhibit two equilibrium states which are categorised as the disease-free (DFE) and pandemic equilibrium states. The reproductive number for the model was computed and used to establish the stability analysis for both equilibrium states. Center manifold theory was employed to assess the bifurcation analysis of the model and the result shows that the model exhibits forward bifurcation when the reproductive number is greater than and equal to 1.
FORECASTING THE UNEMPLOYMENT RATE IN MALAYSIA DURING COVID-19 PANDEMIC USING ARIMA AND ARFIMA MODELS
Authors: ISMAIL NUR AFIQAH , RAMZI NURIN ALYA , Mah Pauline Jin Wee
Published: March 2022

The unemployment issue is one of the most common problems faced by many countries around the world. The unemployment rates in developed countries often fluctuate throughout time. Similarly, Malaysia is also affected by the inconsistent unemployment rate especially during the COVID-19 pandemic. Therefore, in order to understand the trend better, ARIMA and ARFIMA were used to model and forecast the unemployment rate in Malaysia in this study. The dataset on the unemployment rate in Malaysia from January 2010 until July 2021 was obtained from Bank Negara Malaysia (BNM) official portal. The best time series models found were ARIMA (2, 1, 2) and ARFIMA (0, −0.2339, 0). The performance of the models was evaluated using mean absolute percentage error (MAPE), mean absolute error (MAE) and root mean square error (RMSE). It appeared that the ARFIMA model emerged as a better forecast model since it had better performance compared to ARIMA in forecasting the unemployment rate in Malaysia.
Screening of composite substrates suitable for tissue-cultured plantlets growth of Asparagus cochinchinensis (Lour.) Merr
Authors: Yu Xiaosong , Li Lin , Li Yongquan , Liu Zhi , Yang Ningxian , Zhang Mingsheng
Published: March 2022

Asparagus cochinchinensis (Lour.) Merr is a medicinal, edible and horticulture plant. Seedling breeding relies on tissue-cultured technology, but the transplant from tissue-cultured seedlings to field cultivation poses a problem in the large-scale production of A. cochinchinensis. Tissue-cultured seedlings of A. cochinchinensis were used as materials, and they were transplanted into the substrates that were mixed with coconut bran, peat, vermiculite, perlite or garden soil. The analysis of the physical and chemical properties of the substrate, combined with the survival rate of seedlings, the aboveground parameters (plant height, stem diameter, fresh weight and dry weight), underground parameters (root fresh weight, root dry weight, root length, root diameter, root surface area and root volume) and physiological indexes (malondialdehyde, soluble protein, soluble sugar, proline, chlorophyll and root vigour), allow us to understand the effects of different combination substrates on the growth and physiology of A. cochinchinensis tissue-cultured seedlings. We concluded that the survival rate of seedlings was negatively correlated with the bulk density and conductivity and was positively correlated with the porosity in the substrate. The membership function was used to comprehensively evaluate the indexes of each combination substrate, and it was concluded that coconut bran:perlite:vermiculite = 33.33%:33.33%:33.33% (bulk density = 0.23 g · cm−3, total porosity = 65.07%, pH = 6.30, conductivity = 0.51 mS · cm−1) scored the highest, the survival rate of seedlings reached 87.10%, the aboveground and underground growth were vigorous and the quality was better than other substrates. This research provides technical support for the efficient cultivation of tissue-cultured seedlings of A. cochinchinensis and reduces the cost of raising seedlings.
Anticancer activity and apoptotic induction of Chromolaena odorata Linn leaves extract and fractions on hepatocellular carcinoma cell lines (HepG2)
Authors: YUSUF HANIFAH , FAHRIANI MARHAMI
Published: March 2022

The purpose of this study is to screen and to evaluate anticancer activity and apoptosis induction of Chromolaena odorata (C. odorata) leaves extract and its fractions on HepG2 cancer cell lines. The C. odorata leaves were extracted by maceration using ethanol 80% then fractionated by using n-hexane, ethyl acetate and ethanol. MTT assay method was used to evaluate anticancer activity and flowcytometri method used to evaluate the induction of apoptosis. The phytochemical analysis and  characterization of the major compound of the extract and the fractions were done by using Liquid Chromatography-Mass Spectroscopy (LCMS). The phytochemical analyis showed that the crude ethanolic extract and fractions of C. odorata leaves contains alkaloid, flavonoids, phenolic, steroids, tannin and saponin. The result of LCMS shown the major compounds of the extract and fractions are 5,7,8,3′,4′-Pentamethoxyflavonone, 1-Carboethoxy-β-carboline, 3-Methylcanthin-2, 6- dion, Canthin-6-one. In the n-hexane fraction obtained 5,7,8,3′,4′-Pentamethoxyflavonone, Methyl ophiopogonanone A and Pd-C-Ⅱ. Meanwhile, in the ethyl acetate fraction contained, 3-(3′,4′-Dihydroxybenzyl)-7-hydroxychroman-4-one, 3-(4'-Hydroxy-benzyl)-5,7-dihydroxy-6-methyl-8- methoxy-chroman-4-one, Methyl opiopogonanone A and Sinensetin. The ethanol fraction, contained the compound 3-(3′,4′-Dihydroxybenzyl)-7-hydroxychroman-4-one, 3-(4'-Hydroxy-benzyl)-5,7-dihydroxy-6-methyl-8- methoxy-chroman-4-one and Methyl opiopogonanone A. The crude ethanolic extract, n-hexane fraction, ethyl acetate and ethanol fraction extract have anticancer activities with IC50 value of 23.44 mg/mL, 84.52mg/mL; 88.51mg/mL; and 167.49 mg/mL respectively. This research suggests the crude ethanolic extract of Chromolaena odorata leaves has a potential candidate for hepatocarcinoma treatment.
Analysis of Factors Influencing the Performance of Regional Government Apparatuses
Authors: Dewi Muliyati  , Andi Mattulada Amir  , Muhammad Din  , M. Ikbal A  , Abdul Pattawe
Published: March 2022

This study aims to examine and analyze the effect of Public Accountability, Decentralization Structure, Clarity of Budget Target and Managerial Roles of Regional Financial Managers on the Performance of Local Government Officials on Financial Managers of Regional Apparatus Organizations in Palu City. This is a quantitative study, and the data was gathered by a survey approach utilizing a questionnaire as the tool. Porposive sampling was used to obtain the sample, which included the head of the OPD and the head of the financial sub-section in each Palu City OPD. PLS, with the help of WarpPLS software, is the analytical tool used to manage the data. The findings show that public accountability affect the performance of local government officials. The structure of decentralization affects the performance of local government officials, clarity of budget targets affects the performance of local government officials, and the managerial role of regional financial managers affects the performance of local government officials.
Uji Aktivitas Antioksidan dan Antidiabetes Ekstrak Daun Mangrove Rhizopora mucronata
Authors: Usman Usman , Fildzania Dwi , Fauzi Imam
Published: March 2022

Penelitian ini bertujuan untuk mengetahui kandungan senyawa metabolit sekunder dan antioksidan serta antidiabetes ekstrak diklorometan dan etil asetat daun mangrove Rhizopora mucronata. Tumbuhan sampel yang digunakan diambil di pesisir pantai Muara Badak. Sampel daun mangrove R. mucronata yang telah dikeringkan diekstrak dengan metode maserasi menggunakan pelarut methanol dan dilanjutkan dengan proses ekstraksi secara partisi cair-cair menggunakan pelarut n-heksan, diklorometan dan etil asetat. Ekstrak diklorometan dan etil asetat daun mangrove Rhizopora mucronata dilanjutkan dengan uji fitokimia menggunakan uji warna, uji aktivitas antioksidan dengan metode DPPH, uji antidiabetes menggunakna metode uji toleransi glukosa oral (UTGO). Hasil uji fitokimia ekstrak diklorometan dan etil asetat daun mangrove Rhizopora mucronata positif mengandung senyawa metabolit golongan alkaloid, flavonoid, tannin, dan fenolik. Hasil uji aktivitas antioksidan dari ekstrak total diklorometan memiliki nilai IC50 sebesar 70,38 ppm dan hasil uji antidiabetes berdasarkan persentase penurunan kadar glukosa darah mencit yang paling tertinggi terjadi pada mencit kelompok V dengan dosis 250 mg/kgBB yaitu sebesar 68,78%. Hasil uji aktivitas antioksidan dari ekstrak total etil asetat memiliki nilai IC50 sebesar 59,89 ppm sedangkan untuk hasil uji antidiabetes ekstrak etil asetat berdasarkan persentase penurunan kadar glukosa darah mencit yang paling tertinggi terjadi pada mencit kelompok IV dengan dosis 125 mg/kgBB yaitu sebesar 28,89%. Berdasarkan data tersebut dapat dikatakan bahwa ekstrak total diklorometan dan etil asetat memiliki aktivitas antioksida dengan kategori kuat. Ekstrak diklorometan berpotensi sebagai antidiabetes karena mampu menurunkan kadar glukosa dengan persentase penurunan kadar glukosa yang tertinggi.
Analisis Efektivitas Biaya Pasien PROLANIS DM Tipe 2 di Puskesmas Kota Bandung
Authors: Ulfah Ulyati , Halimah Eli , Suwantika Auliya A
Published: March 2022

Diabetes mellitus is one of chronic diseases with high treatment cost. Purpose of this research was to analyze the cost-effectiveness of (Prolanis) for patients with type 2 DM and to establish the most significance parameter affecting the cost-effectiveness value. This study is a non-experimental retrospective by collecting medical record data of Prolanis patients with type 2 DM at Bandung Health Center during 2015 and 2016 with 246 samples that met the inclusion criteria. Cost-effectiveness analysis was conducted by calculating Average Cost Effectiveness Ratio (ACER) and Incremental Cost Effectiveness Ratio (ICER). In particular, sensitivity analysis was conducted to investigate the most significance parameter affecting those ratios. The result of unpaired t test confirmed that there was not significance difference on ACER values of 2015 and 2016, whereas the value of arithmetic (0,202) < t table (4,303) with significance value ? 0,04 <0,05. The implementation of Prolanis in 2015 (ACER = Rp. 1.095,97) seemed to be more cost effective than in 2015 (ACER = Rp. 1.268,96). Cost of biguanida drugs is the most influential factor affecting the cost-effectiveness values of Prolanis implementation in patients with type 2 DM in 2015 and 2016.
Literature Review tentang Hubungan Psikologis terhadap Kejadian Hiperemesis Gravidarum
Authors: Anshory Vaya Luthfi Salsabila , Hasanah Nurul , Ngo Novia Fransiska
Published: March 2022

Nausea and vomiting affect up to >50% of pregnancies. Hyperemesis gravidarum is vomiting that occurs in early pregnancy until 20 weeks of gestation. The incidence of hyperemesis gravidarum in Indonesia is still quite a lot. The cause of this disease cannot be known with certainty, but it is carefully adjusted by thyroid hormone, Helicobacter pylori infection, and psychology. This study use literature review as a research method. This literature review study aims to determine the relationship between psychology on the hyperemesis gravidarum occurrence. Searches were performed by searching articles using electronic databases or search engines i.e Google Scholar, Harzing’s Publish, and Pubmed. The year of publication was limited between 2016 and 2021 in  Indonesian and English language. The results were obtained 27 studies from International and Regional journals that are suitable with the inclusion criteria. The number of samples was 654.363 pregnant women are devided into case and control groups. The results of this literature review showed that psychology was found to be associated with hyperemesis gravidarum (96,3%). It can be concluded that psychological factors were found to be associated with the hyperemesis gravidarum occurrence.
ONDE ESTÁ A SABEDORIA? (Jó 28,12): OS LIMITES DO CONHECIMENTO HUMANO
Authors: Andrade Aíla Luzia Pinheiro de , Morais Augusto Lívio Nogueira de
Published: March 2022

É de suma importância conhecer o desenvolvimento histórico do sistema sapiencial no antigo Israel para compreender o contexto do surgimento do cristianismo dentro do judaísmo plural no período do segundo Templo. Sendo assim, o artigo tem como objetivo pesquisar a crise sapiencial e suas repercussões teológicas e sociológicas não somente para os séculos VI aC – I dC, mas também para as gerações futuras.O estudo foi realizado através da pesquisa bibliográfica de natureza qualitativa e com enfoque hermenêutico. A pesquisa tem por base teórica os textos bíblicos BÍBLIA (2002), com o estudo do vocabulário hebraico em STRONG (1995), uma visão geral sobre o desenvolvimento do movimento sapiencial a partir de ASENSIO (2008) e a inacessibilidade da sabedoria no livro de Jó tomando por base a tese de DELL (1991). O artigo está estruturado em dois momentos principais: o desenvolvimento da sabedoria até sua identificação com a Torá; as questões sobre acessibilidade e inacessibilidade da sabedoria. Os resultados obtidos com a pesquisa destacam que após perceberem a acessibilidade da sabedoria que se manifesta tanto na criação (sua universalidade) quanto na sua identificação com a Torá (sua particularidade), os sábios do antigo Israel, chegaram à conclusão que é na experiência existencial com o Senhor que o ser humano encontra a sabedoria.
Indicators for Disaster Vulnerability to the Overflowing of the Niger River in Adjoining Settlements in the Confluence City of Lokoja, Nigeria
Authors: Popoola Ayobami Abayomi , Adeleye Bamiji Michael , Adeniji Kayode Nelson , Babalola Taiwo Oladapo , Magidimisha-Chipungu Hangwelani Hope
Published: March 2022

River overflow is one of the main causes of flooding and erosion. In Nigeria, flooding affects (loss and damage to properties and distortion of sources of livelihood) and displaces more people than any other disaster (loss and damage to properties and distortion of sources of livelihood). The 2012 overflowing of the River Niger and the subsequent flooding of Lokoja historically represent the most devastating natural disaster in the city. The study was based on the Geographic Information System’s (GIS) Multi Criteria Analysis (MCA) and examined the risk and vulnerability of Lokoja’s settlements adjoining the Niger River to flooding. The criterion considered were elevation, land cover, slope, curvature, flow accumulation, the Normalised Difference Water Index (NDWI) and the drainage density of the study area. The data used for this study was obtained from a secondary source United States Geological Survey (USGS). The relationship between the NDWI and the precipitation in Lokoja showed that the NDWI and precipitation were inversely related. This implied that an increase in precipitation was consequential to the intensity of the water index in the study area. This study successfully showed the capability of remote sensing and the GIS to assess both pre- and post-disaster (flooding) vulnerability. It also revealed that high precipitation and increasing physical development due to urbanisation in lowlands increased the vulnerability of an area to flooding. The recommendation forwarded was the need for improved river basin management and flood disaster prevention.
An insight into neurotoxicity effects associated with Organophosphate exposure
Authors: Choudhury Suman , Kalita Jogen Chandra
Published: March 2022

Organophosphates comprise several groups of chemicals derived from phosphonic, phosphinic and phosphoric acids. The chemicals cause four major neurotoxic disorders: cholinergic syndrome, chronic organophosphate-induced neuropsychiatric disorder (COPIND), intermediate syndrome and organophosphate-induced delayed polyneuropathy (OPIDP). In the cholinergic syndrome, organophosphates exert their toxic effect through the inhibition of acetylcholinesterase. Patients with cholinergic syndrome experience several symptoms including sweating, lacrimation, salivation and rhinorrhea and respiratory difficulties. The primary symptoms in the intermediate syndrome are respiratory and proximal limb muscle weakness. In contrast, psychiatric conditions, such as depression and anxiety, have been reported in patients with COPIND. In OPIDP, patients experience acute cramping pain inside their calves and itchiness in the hands and feet, paresthesia and distal unresponsiveness.
Multiplex PCR: A Molecular Modality for Rapid Detection of CTX-M-15, AAD A1 and QNR S1 Genes among Drug Resistant Clinical Isolates of Enterobacteriaceae in Kanchipuram, South India
Authors: Rubala Nancy J. , Gururajan Gayathri , Murugan N. , Kaliyaperumal Kathireshan
Published: March 2022

Multidrug resistance is a potential threat to the mankind. The prevalence rate of multidrug resistant bacteria is worrisome and has gained significant attention globally. Hence it becomes imperative for clinical laboratories to identify these multidrug resistant pathogens for appropriate therapy. It is equally important to detect the resistance mechanisms which would aid in understanding and development of new therapeutic options. This study was carried out to identify the prevalence of multidrug resistant Enterobacteriaceae from clinical samples recovered from Kanchipuram district. The study was also implicated in designing of novel primers using primer3 tool and standardizing a multiplex PCR targeting ctxm- 15, aadA1, qnrS1 genes in the isolates. Of the 60 clinical isolates studied, 14, 13 and 12 isolates harbored ctx-m-15, qnrS1 gene and aadA1genes respectively. Among these, 2 isolates carried both ctx-m-15 and qnrS1 genes and 3 isolates were found to carry both ctx-m-15 and aadA1 genes. 1 isolate was found to be positive for both aadA1 and qnrS1 genes. None of these isolates harbored all the three targeted genes qnrS1 and aadA1, ctx-m-15. The present study will aid in detecting drug resistant genes like ctx-m-15, aadA1, qnrS1 in clinical isolates with higher sensitivity and specificity and will also reduce the cost of reaction than that required for uniplex PCR. The prevalence rate of drug resistant genes among Kanchipuram district alerts us for the measures needed to be undertaken to control the spread of drug resistant genes in community.
Organo catalytic construction of novel Pyrazol-2-Indolinone derivatives
Authors: B. Raja Sekhara Reddy , Malleswara Reddy P. , Surendra Babu G. , Venkata Narayana V. , Sudhakar Babu K.
Published: March 2022

A few novel series of pyrazol-2-indolinone entities have been designed and synthesized using pyrazalone and α, β-unsaturated oxindole esters as starting materials (5a–j). The chemical structures of the new synthesized compounds were characterized by 1H NMR, 13C NMR, MS spectroscopy and elemental analysis. This procedure provides a highly efficient and facile route to functionalized pyrazol-2-indolinones from readily available substrates under mild reaction conditions.
Exposure to 7, 8 Dihydroxycoumarin protects Cadmium induced toxicity effect in Zebrafish (Daniorerio) embryos
Authors: Dharmar Manimaran , Varatharajan Renuka , Saravanan Ramesh , Kavitha Govarthanan , Namasivayam Elangovan
Published: March 2022

Cadmium (Cd) is one of the precedence pollutants in the environment which menaces the aquatic organisms. Cd is also shown to have deleterious health impairments causing male and female infertility in humans. In this study, we investigated the role of 7, 8- DHC as a potent rescuer of Cd induced toxicity using zebrafish (Daniorerio) model. The anti-oxidant property of 7,8-DHC was analysed and confirmed using 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric ion reducing power (FRAP) and hydroxyl radical (OH) assays. Further, we induced Cd toxicity in zebrafish embryos at 100-μM concentration and the intoxicated embryos showed a significantly reduced survival, delayed hatching and phenotypic aberrations at 24, 48, 72 and 96 hours post fertilization (hpf). Similarly, Cd intoxicated embryos showed an expressively increased cardiac function (170 ±1 beats/min and 172± 1 beats/min) at 48 and 60 hpf. Furthermore, the rescuing effect of 7,8-DHC was analysed via treatment of Cd intoxicated embryos at dosage dependent manner. At 100 μg, 7,8-DHC showed significantly reduced heart beat compared to the Cd intoxicated embryos. Moreover, 50 and 100 μg of 7, 8-DHC treated groups showed 103± 1 beats/min and 104±1 beats/min respectively. Histopathological interpretations revealed the rescuing effects on notochordal segmentation at 50 and 100 μg 7, 8-DHC in Cd intoxicated embryos at 96 hpf. Overall, our results clinched that 7, 8-DHC could act as a potent redox scavenger against Cd toxicity.
Isolation and characterization of an effective biofuel producing oleaginous Cutaneotrichosporon curvatum BRV096
Authors: Addagatla Ravindar , Raja Rao P.
Published: March 2022

Globally, demand for the fuels is increasing day by day leading to the depletion of fuel resources and increase in the fuel prices. Need for an alternative cost effective and eco- friendly fuel has become the first priority. In this scenario, oleaginous microbes were introduced which have a remarkable ability to accumulate lipids when compared to the plant sources. Among all the oleaginous microbes, yeast is proven to be showing high lipid accumulation i.e. up to 60% of its total cell weight. In the current research work, potent high lipid accumulating yeast was isolated from the soil samples collected from the municipal dump yard. Out of the 96 microbial isolates, 12 potent strains were screened which were further purified and stored in refrigerator at 4oC. Among all the microbial strains, BRV096 showed high dry cell weight and lipid accumulation (52±2.8 g/L and 23±2.9 ml/L) followed by BRV007 (48±2.7 g/L and 18±3.8 ml/L). BRV096 was studied morphologically by using Scanning electron microscope which revealed the structure as oval. Budding cells are typical characteristics of the yeast. 18 S rRNA sequencing was carried out and the obtained DNA sequence data was searched in BLASTn which showed 99.9% similarity with Cutaneotrichosporon curvatum. With a motto to assess the fatty acid methyl esters composition, FAME analysis was carried out which revealed the composition as palmitoleic acid (C16:1, 71.16%), oleic acid (C18:1, 17.26%) and eicosapentaenoic acid (C20:5, 11.58%). The fatty acids methyl esters profile produced by Cutaneotrichosporon curvatum BRV096 showed similarity with the biodiesel profile. Current research results states that Cutaneotrichosporon curvatum BRV096 can be effectively used in the production of biodiesel.