bluuebunny/crossref_metadata_2025 huggingface dataset:
Diabetic Foot Infection with Bacteroides pyogenes
Authors: Shenoy Padmaja Ananth , Vishwanath Shashidhar , Nagaraj Ravikumar Terikere , Banerjee Barnini , Krishna M. Sunil
Published: August 2021

>Diabetic foot infections are the most common serious diabetes-related complication posing significant socioeconomic burden on the health-care system. Diabetic foot microbiota consists of polymicrobial flora with predominance of Gram-negative aerobes and anaerobes. Here, we report a rare case of diabetic foot infection by Bacteroides pyogenes, an obligate Gram-negative anaerobic bacillus which is commonly encountered in polymicrobial animal bite wound infections.
Epidemiological Profile, Clinical, Paraclinical, and Evolutionary of Adult Autoimmune Cytopenia Cases in East of Algeria
Authors: Chettoum Aziez , Guedri Kamilia , Djerrou Zouhir , Khatabi Latifa , Boudjerda Saida , Djeffali Roumeissa
Published: August 2021

BACKGROUND:

Peripheral autoimmune cytopenia is defined by the immune-mediated destruction of hematological cell lines, including platelets, red blood cells, white cells (neutrophils), and multi-line destruction, called Evans syndrome.

METHODS:

Our retrospective study includes 59 patients admitted to the hematology service in Constantine Regional Military University Hospital during a period of 10 years (2010–2019) with the aim of specifying the epidemiological, clinical and biological characteristics as well as the characteristics therapy of adult autoimmune cytopenia in eastern Algeria region.

RESULTS:

Through this study, it can be noted that immunological thrombocytopenic purpura (ITP) is the most frequent of cytopenia 79.33% (47 cases) followed by autoimmune hemolytic anemia (AHAI) by 20.34% (11 cases). The average age for ITP is 52.04 ± 5.78 years with a male predominance and a gender F/M ratio of 0.81. People over the age of 60 were the most affected. The diagnosis is evoked in the presence of a hemorrhagic syndrome in 51.06% of cases. Thrombocytopenia (platelet count <100 g/l) is found in all our patients. Of the 24 cases with hemorrhagic syndrome, 83.33% have thrombocytopenia <30 g/l. The average age for AHAI is 46.92 ± 10.16 years with a gender F/M ratio of 0.71. The diagnosis is evoked in the presence of an anemic syndrome in 91.66% of cases. Anemia is found in all our patients, with an average hemoglobin level of 7.56 ± 0.95 g/dl. Direct positive test in 66.67% of cases. The markers of hemolysis remain mainly disrupted by the haptoglobin which is reduced with an average rate of 0.06 g/l.

CONCLUSION:

Peripheral autoimmune cytopenia is rare; we can remember that in our context ITP is the most frequent of autoimmune cytopenia in adults. It's a pathology that affects both sexes with a male predominance. In the AHAI, we have noticed a slight male predominance. Its main clinical manifestation is anemic syndrome and corticosteroids are the first-line treatment in both types ITP and AHAI.
A Review of the Pathological Mechanisms and Clinical Implications of Coagulopathy in COVID-19
Authors: Singh Suvir , Jain Kunal , Paul Davinder , Singh Jagdeep
Published: August 2021

Coronavirus disease-19 (COVID-19) is an ongoing global pandemic with approximately 15% of patients requiring mechanical ventilation and intensive care unit care. The mechanisms of end-organ damage and mortality in severe COVID are slowly being unraveled. COVID-related coagulopathy is a characteristic syndrome that plays a key role in multi-organ dysfunction and severe disease. Mechanistically, many components including endothelial cells, the coagulation system, complement system, cytokines, and NETosis are involved in the pathogenesis of this syndrome and provide potential therapeutic targets. We provide a focused review on the current understanding of COVID-19-related coagulopathy and its therapeutic implications.
COVID-19 Vaccines and their Potential use in Patients with Hematological Malignancies
Authors: Dada Ashraf , Al-Bishi Ghadeer , Usman Binyam
Published: August 2021

Many uncertainties exist regarding COVID-19 vaccination in patients undergoing treatment for hematological malignancies. We intend the illustrate the various types of COVID-19 vaccine currently in use and their mechanism of action. We have complied, recommendations for COVID-19 vaccination in patients suffering with specific hematological malignancies and those undergoing HCT and CAR-T cell therapy in this review. We have also discussed the available safety data for COVID-19 vaccination in the immunocompromised population.
HPV-16 Detection and Quantitation in Whole Mouth Fluid of Oral and Cervical Cancer Patients
Authors: Divya Bose , Rao Uma Devi K. , Thavarajah Rooban , Joshua Elizabeth , Ranganathan Kannan
Published: August 2021

Introduction:

The association of human papillomavirus (HPV) in cervical and oropharyngeal cancer is well established. There is a growing evidence that HPV could possibly contribute to oral cancer along with alcohol and tobacco use. The aim of this study was to evaluate and quantify HPV-16 in the whole mouth fluid of patients with oral squamous cell carcinoma (OSCC), cervical cancer, and normal controls.

Materials and Methods:

The whole mouth fluid of 20 patients with OSCC (Group I), 10 with cervical cancer (Group II), and 10 normal individuals (Group III) was collected by the spit technique. The DNA was extracted and quantified by quantitative polymerase chain reaction. Data were analyzed by SPSS 21 (IBM Corp. Released 2012, Armonk, NY: IBM Corp) software and analysis of variance test was used.

Results:

The mean age of Group I patients was 50.9 ± 13.5 years, Group II was 51.6 ± 8.07 years, and Group III was 46 ± 8.5 years. In Group I, 15 were males and 5 were females. In Group III, 5 were males and 5 were females. Eight patients belonging to Group I, four of Group II, and seven of Group III had HPV-16 in their whole mouth fluid.

Conclusion:

HPV-16 was identified in the whole mouth fluid of OSCC, patients with cervical cancer, and even in normal controls. However, the mean viral loads were highest in patients with cervical cancer followed by patients with OSCC and normal controls.
Oral Manifestations of COVID-19 Patients
Authors: Karthika P.S. , Rathy R. , Jayanthi P. , Harish R. K. , Ameena M. , Krishnasree R.J.
Published: August 2021

Introduction:

The emergence of coronavirus disease 2019 (COVID-19) crisis has evoked an exigent need to explicate the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and oral mucosal lesions. The present systematic review aims to elucidate the recent literature on oral manifestations related to COVID-19 so as to help the dental professionals for better screening and early diagnosis of the disease.

Materials and Methods:

A comprehensive literature search on PubMed, Science direct, Scopus, and Embase databases was carried out from December 2019 to March 2021 using keywords “Coronavirus,” “COVID-19,” “SARSCoV-2,” “Oral mucosal lesions,” and “Oral manifestation.” Additional information was obtained from Cochrane, World Health Organization, and Medscape. The full text articles of case reports and cross-sectional studies were analyzed and included. The review included 25 articles.

Results:

Four most common oral manifestations were found: gustatory and olfactory dysfunction, xerostomia, oral mucosal lesions, and salivary gland diseases. Vasculitis, opportunistic infections, drug eruption secondary to administration of Non-Steroidal Anti-inflammatory Drugs (NSAIDs), stress, immunosuppression, and hyperinflammatory immune response secondary to COVID-19 might be some of the relevant predisposing factors responsible for the onset of oral manifestations in patients with COVID-19.

Conclusion:

The early detection of oral symptoms of SARS-CoV-2 infection could help the clinicians to perform a better screening, and in recognizing early manifestations of the disease. However, the oral manifestations might be misdiagnosed due to subsequent challenge of undergoing oral examinations, hence diverse studies should be undertaken by the researchers to gain a better insight into the topic.
Mental health outcomes among health-care workers dealing with COVID-19/severe acute respiratory syndrome coronavirus 2 pandemic
Authors: Dutta Abhijit , Sharma Avinash , Torres-Castro Rodrigo , Pachori Hariom , Mishra SukhDev
Published: August 2021

Introduction:

The psychological impact of COVID-19 on health-care workers (HCWs) has received attention from researchers to understand the extent of the effects of the ongoing pandemic on this population. The aim of this systematic review and meta-analysis was to synthesize the currently available literature on the topic to determine the prevalence of mental health problems in HCWs.

Materials and Methods:

We conducted a systematic review and meta-analysis, searching PubMed, PsycINFO, Scopus, and Cochrane Library databases for articles published from December 2019 to August 15, 2020. We identified studies reporting the prevalence of any mental health condition in HCWs involved directly or indirectly in providing services during the COVID-19 pandemic. The prevalence proportion for individual outcome was extracted as an estimate of interest. We performed random-effects meta-analyses evaluated using Q statistic, I
2 statistic, subgroup analyses, and sensitivity analyses and assessed study quality. This review was done in adherence to the Reporting Items for Systematic Reviews and Meta-Analysis and Meta-analysis of Observational Studies in Epidemiology guidelines. The study protocol was registered prospectively at PROSPERO (CRD42020182005).

Results:

We identified 1958 studies, of which 33 studies including 39703 participants (with a median = 393; range = 88–14825) were finally included for analysis. The estimated overall prevalence were as follows: depression 32.4% (95% confidence interval [CI]: 25.9–39.3, I
2 = 99%), anxiety 32.5% (95% CI: 26.4–39.0, I
2 = 99%), insomnia or sleep disturbance 36.6% (95% CI: 36.6–48.3, I
2 = 99%), and stress 37.7% (95% CI: 24.0–52.3, I
2 = 100%).

Conclusion:

HCWs who are dealing with the COVID-19 pandemic have a significant prevalence of depression, anxiety, insomnia and poor sleep quality, and stress. The health-care workforce needs to practice self-care now more than ever, while health-care managers and policymakers need to factor in the mental health consequences of COVID-19 on their workforce.
Sexual dysfunction in clinically stable patients with bipolar disorder receiving valproate
Authors: Grover Sandeep , Mehdi Abbas , Kumar Ajay , Chakrabarti Subho , Avasthi Ajit
Published: August 2021

Aim:

This study evaluated the prevalence of sexual dysfunction in patients with bipolar disorder, while receiving valproate monotherapy.

Materials and Methods:

Sixty-three clinically stable patients with bipolar disorder were evaluated on the Arizona sexual experience scale (ASEX), Udvalg for Kliniske Undersogelser (UKU) other side effect subscale and brief adherence rating scale.

Results:

The mean age of the study sample was 38.84 (standard deviation: 12.49) years. About three-fourth of the participants were male (76.2%). About one-fourth (28.6%) were found to have sexual dysfunction as per the ASEX. In terms of dysfunction in specific domain of sexual functioning, depending on the cut-off used, problem with sexual desire varied from 13.33% to 35.41% among males and 6.66%–46.66% in females. Erectile dysfunction was seen in 13.33%–31.25% of males and difficulty in vaginal lubrication was reported by 13.33%–26.66% of females. When those with and without sexual dysfunction as per the ASEX were compared, it was seen that those with sexual dysfunction had significantly longer duration of illness, higher prevalence of abnormal blood pressure and higher mean scores on the UKU other side effect subscale. Both the groups did not differ on other clinical variables.

Conclusion:

A significant proportion of patients receiving valproate experience sexual dysfunction. Higher prevalence of sexual dysfunction was associated with longer duration of illness, higher prevalence of abnormal blood pressure, and higher mean scores on UKU other side effect subscale.
A study of thyroid profile in patients suffering from the first episode of mania
Authors: Goyal Manish Kumar , Yadav Kuldeep Singh , Solanki Ram Kumar
Published: August 2021

Background:

Thyroid function is commonly considered in the assessment of mood disorders. Reports of thyroid dysregulation in patients with mania are associated with several confounding factors. To eliminate confounding factors, studies of first-episode mania are desirable. This study tried to find out any relationship between thyroid disorders and mania.

Aim:

The aim of this study is to assess and compare the thyroid profile between first-episode mania and healthy controls and to ascertain the correlation between severity and duration of the manic episode with FT3, FT4, and thyroid-stimulating hormone (TSH) levels.

Materials and Methods:

This was a cross-sectional study conducted in the psychiatry department of a tertiary care hospital. Forty consecutive drug-naïve patients with first-episode mania, diagnosed according to the International Classification of Disease-10 (study group), were matched with 40 healthy controls (control group). Both the groups were compared on the basis of thyroid profile and thyroid levels were correlated with duration and severity of illness in the study group.

Results:

Nearly 7.5% of cases in the study group had hyperthyroidism, whereas 5% had subclinical hyperthyroidism. In contrast, normal controls showed 5% and 10% prevalence of hypothyroidism and subclinical hypothyroidism, respectively. A statistically significant lower level of TSH was observed in the study group (P < 0.001), whereas the mean serum levels of FT3 and FT4 were higher in the study group, but the difference was statistically nonsignificant. No significant correlation of thyroid hormones level with duration and severity of illness was noted.

Conclusion:

Our findings highlight a higher prevalence of hyperthyroidism in patients with mania and suggest the role of thyroid hormones in mania.
Relapse in opioid dependence
Authors: Sureshkumar Kailash , Dalal Pranab Kumar , Kailash Shabeeba Z. , Rudhran Vidyendaran
Published: August 2021

Background:

Although our understanding about neurobiology of opioid dependence and availability of pharmacological treatment has gone a long way in the last few decades, psychosocial interventions play a pivotal role in the prevention of relapse owing to reasons such as less treatment-seeking behavior and poor penetrance of opioid substitution treatment. There are many studies assessing psychosocial factors in alcohol and nicotine dependence, yet the availability of such studies for opioid dependence is sparse. This study aimed at evaluating the association of relapse in opioid dependence with various psychosocial factors.

Materials and Methods:

This was a cross-sectional study with two groups of opioid dependence patients: In abstinence (N = 28) and relapse (N = 33). Psychosocial variables such as high-risk situations, coping behavior, stressful life events, self-efficacy, and social support were assessed in the two groups and analyzed for the association with opioid relapse.

Results:

This study reports that more high risk situations (odds ratio [OR] =1.58; 95% confidence interval [CI] =1.22–2.03; P = 0.017), especially negative mood state and undesirable stressful life events (OR = 2.08; 95% CI = 1.28–3.37; P = 0.05) were significantly associated with higher odds of relapse in patients of opioid dependence. Further, higher self-efficacy (OR = 0.92; 95% CI = 0.87–0.96; P = 0.017) was significantly associated with lower odds of relapse.

Conclusion:

Psychosocial factors such as high risk situations, undesirable stressful life events, and self-efficacy were significantly associated with relapse in opioid dependence. Hence, practice of a holistic, multimodal, and individualized treatment plan addressing these factors might help in reducing the relapse rates in them.
Predictors of retention in the treatment for opioid dependence
Authors: Shouan Anish , Ghosh Abhishek , Singh Shubh Mohan , Basu Debasish , Mattoo Surendra Kumar
Published: August 2021

Background:

Literature on a longitudinal study of the determinants of treatment retention for patients with opioid dependence is limited.

Aim:

To find out patient- and treatment-related (buprenorphine-naloxone-assisted treatment [BNX treatment] versus naltrexone treatment) predictors for retention in maintenance treatment.

Materials and Methods:

A total of 100 participants with opioid dependence were recruited by convenience sampling. The primary outcome was treatment retention – 3 months and 6 months postentry into maintenance treatment. Multiple assessments were done for the severity of opioid dependence and withdrawal, high-risk behavior, quality of life, and recovery capital – baseline and 3 and 6 months. The secondary outcome was to assess the change observed in the above-listed variables.

Results and Conclusions:

Bivariate analysis across retained and the dropout groups brought out significant differences for some (type of opioids and route of administration) but not for other (age, employment, and education) patient-related factors. Multivariate analysis, adjusting for the type of maintenance treatment, rendered these associations statistically insignificant. BNX-based treatment (compared to naltrexone maintenance) was the most significant predictor of treatment retention both at the end of 3 months and 6 months. Even after controlling for the severity of opioid dependence and withdrawal, type and route of opioid use, and high-risk behavior, patients on BNX were eleven times (14 times at the end of 6 months) more likely to be retained in the treatment. BNX group had significant improvements in the domains of recovery capital, quality of life, addiction severity, and severity of opioid dependence. There is a need to scale up the BNX-assisted treatment program in India and elsewhere.
A systematic review of Indian studies on sexual dysfunction in patients with substance use disorders
Authors: Sarkar Siddharth , Chawla Nishtha , Tom Ashlyn , Pandit Prabhat Mani , Sen Mahadev Singh
Published: August 2021

Background and Aims:

Sexual dysfunction is often associated with substance use disorders. This study aimed to synthesize Indian literature on sexual dysfunction among patients with substance use disorders.

Materials and Methods:

Electronic search engines were used to identify studies of the last 20 years that reported sexual dysfunction with different substance use disorders. Information was extracted using a predefined template. Quality appraisal of the included studies was carried out using Joanna Briggs Institute checklist.

Results:

Twenty-seven relevant papers were identified that pertained to 24 distinct studies. Most of them were in patients with alcohol dependence, and fewer were in patients with opioid dependence. The study designs were primarily single-group cross-sectional, though many case–control, cross-sectional studies were also identified. The proportion of participants with sexual dysfunction ranged from 22.2% to 76% for studies related to alcohol dependence and 40% to 90% for studies pertaining to opioid dependence. Varied types of sexual dysfunctions were identified, including poor satisfaction, lack of desire, premature ejaculation, and erectile dysfunction. Efforts to address bias and confounders were not reported in most studies.

Conclusion:

Sexual dysfunction affects a substantial proportion of patients with substance use disorders. Clinicians can make an effort to ascertain and address sexual dysfunction in their routine clinical practice while dealing with patients with substance use disorders.
Inhibition of WEE1 Potentiates Sensitivity to PARP Inhibitor in Biliary Tract Cancer
Authors: Seo Hye-Rim , Nam Ah-Rong , Bang Ju-Hee , Oh Kyoung-Seok , Kim Jae-Min , Yoon Jeesun , Kim Tae-Yong , Oh Do-Youn
Published: August 2021

Purpose Up to 20% of patients with biliary tract cancer (BTC) have alterations in DNA damage response (DDR) genes, including homologous recombination (HR) genes. Therefore, the DDR pathway could be a promising target for new drug development in BTC. We aim to investigate the anti-tumor effects using poly(ADP-ribose) polymerase (PARP) and WEE1 inhibitors in BTC.Materials and Methods We used 10 BTC cell lines to evaluate an anti-tumor effect of olaparib (a PARP inhibitor) and AZD1775 (a WEE1 inhibitor) in in vitro. Additionally, we established SNU869 xenograft model for in vivo experiments.Results In this study, we observed a modest anti-proliferative effect of olaparib. DNA double-strand break (DSB) and apoptosis were increased by olaparib in BTC cells. However, olaparib-induced DNA DSB was repaired through the HR pathway, and G2 arrest was induced to secure the time for repair. As AZD1775 typically regulates the G2/M checkpoint, we combined olaparib with AZD1775 to abrogate G2 arrest. We observed that AZD1775 downregulated p-CDK1, a G2/M cell cycle checkpoint protein, and induced early mitotic entry. AZD1775 also decreased CtIP and RAD51 expression and disrupted HR repair. In xenograft model, olaparib plus AZD1775 treatment reduced tumor growth more potently than did monotherapy with either drug.Conclusion This is the first study to suggest that olaparib combined with AZD1775 can induce synergistic anti-tumor effects against BTC. Combination therapy that blocks dual PARP and WEE1 has the potential to be further clinically developed for BTC patients.
Obesity parameters in relation to lung function levels in a large Chinese rural adult population
Authors: Zeng Xiang , Liu Dongling , An Zhen , Li Huijun , Song Jie , Wu Weidong
Published: August 2021

OBJECTIVES: The association between obesity parameters and lung function indicators in the general Chinese rural adult population remains unclear.METHODS: In total, 8,284 Chinese adults aged 20 years to 80 years old from Xinxiang were recruited. Obesity-related parameters, including body mass index (BMI), waist circumference (WC), hip circumference (HC), waist-to-hip ratio (WHR), waistto-height ratio (WHtR), body fat percentage (BFP), basal metabolism, and visceral fat index, and lung function parameters such as forced vital capacity and forced expiratory volume in first second were measured.RESULTS: The total prevalence of obesity defined by BMI, WC, WHR, WHtR, and BFP was 23.2%, 58.2%, 66.7%, 69.2%, and 56.5%, respectively. Spearman correlation analyses showed significant correlations between all obesity-related parameters and lung function. Linear regression analyses further demonstrated that BMI, WHtR, BFP, and general obesity defined using those indicators were negatively associated with lung function, while WC, WHR, and central obesity defined accordingly were positively associated with lung function. The relationship between general obesity and lung function was more evident in women than in men, while the link between central obesity and lung function was more obvious in men than in women.CONCLUSIONS: Obesity is closely related to lung function in the general Chinese adult population. Weight control and loss are important strategies to improve lung function and respiratory health.
Determinants of Socio Economic and Demographic Characteristics of Poverty in Aceh Province
Authors: Wintara Heri , Masbar Raja , Suriani Suriani
Published: August 2021

This study analyzes the effect of socio-economic and demographic characteristics on poverty levels in Aceh Province in the short and long run. Socio-economic characteristics are represented by factors of income per capita, open unemployment rate, and cigarette consumption. While the demographic characteristics are represented by the dependency ratio factor. This study uses panel data from 23 districts/cities in Aceh Province for the 2010-2019 period and the analysis model used is the Autoregressive Distributed Lag (ARDL) panel model. The results found in this study are the dependency ratio factor, cigarette consumption, and the open unemployment rate have a significant effect in the long run on the percentage of poor people. Meanwhile, the significant factors in the short run are the dependency ratio and the open unemployment rate.
Earth System Dynamic Intelligence - ESDI
Authors: Perdigão Rui A. P.
Published: August 2021

Earth System Dynamic Intelligence (ESDI) entails developing and making innovative use of emerging concepts and pathways in mathematical geophysics, Earth System Dynamics, and information technologies to sense, monitor, harness, analyze, model and fundamentally unveil dynamic understanding across the natural, social and technical geosciences, including the associated manifold multiscale multidomain processes, interactions and complexity, along with the associated predictability and uncertainty dynamics. The ESDI Flagship initiative ignites the development, discussion and cross-fertilization of novel theoretical insights, methodological developments and geophysical applications across interdisciplinary mathematical, geophysical and information technological approaches towards a cross-cutting, mathematically sound, physically consistent, socially conscious and operationally effective Earth System Dynamic Intelligence. Going beyond the well established stochastic-dynamic, information-theoretic, artificial intelligence, mechanistic and hybrid techniques, ESDI paves the way to exploratory and disruptive developments along emerging information physical intelligence pathways, and bridges fundamental and operational complex problem solving across frontier natural, social and technical geosciences. Overall, the ESDI Flagship breeds a nascent field and community where methodological ingenuity and natural process understanding come together to shed light onto fundamental theoretical aspects to build innovative methodologies, products and services to tackle real-world challenges facing our planet.
The Mixed Model of Teachers’ Evaluation in Secondary Schools
Authors: Frolov Yury
Published: August 2021

Schools face the need to create a system for managing the performance of teaching employees whose activities are specific, difficult to formalize, and subjected to experiments with different degrees of success throughout the world. This paper deals with providing and management of teacher’s evaluation in Russian schools. The purpose of the study is to develop a teacher evaluation model based on professional qualities and performance indicators. The results of the study were tested on the basis of a survey of teachers after the implementation of the proposed system of assessment tools and evaluation methods. According to teachers, the new system contributes to their continuous professional development and, therefore, to the sustainable development of the educational organization in a competitive environment. The proposed methodology for teachers' evaluation clarifies the general data and meets their expectations, expectations of students and management in terms of correspondence with the development strategies of educational organizations.
Rethinking Management of the 21st Century: Аn Approach to Contemporary Business Education
Authors: Kuzin Dmitry V.
Published: August 2021

This paper is addressing the issues of modern management thinking which became one of the most critical tasks in contemporary business education. Such thinking must reflect all major changes and challenges in science, technology, economy, politics, culture, and society which took place within the first two decades of the 21st century and especially now in the times of pandemic crisis. It is very important not only in terms of analysis but also as an explanation of the patterns of business and management behavior. It became the topic of serious scientific debate of the most prominent business researchers and consultants. The purpose of the article is to develop the methodological approach for further research of modern management and suggest the conceptual model which could structure the analysis of contemporary business reality. The author suggests the conceptual model for further research which could explain the essence of new management revolution. Such open model could be added and interpreted and is already applied in different educational programs in Russia.
The features of the formation of ethno-value consciousness in the modern Kazakh Pedagogical University
Authors: Aipova Ainash , Apaeva Sofiya , Temirgalinova Assel , Shabambaeva Anara , Karabulatova Irina
Published: August 2021

The specifics of the conditions for the formation of the ethno-value consciousness of future teachers based on a comprehensive approach to mastering their ethnic knowledge and skills in the process of competence and activity approaches is the goal of study. The authors used a synergistic approach based on competence-based and activity-based approaches. These approaches include the following methods: interiorization of internal cognitive activity with cross-cultural, cross-competent, cross-linguistic analyses, the method of emotional experience; frame modeling method, competence approach, psycholinguistic and pedagogical experiments. The results the essence of the ethno-value consciousness of the individual is determined; the types of values reflected in the ethno-value consciousness of the individual in the mental form are described, its specificity is revealed; the definition of the ethno-value competence is given and its components are clarified; it is proved that the main methods of forming the ethno-value consciousness of the individual is the event-activity method of reproducing the cultural scenario in order to actualize the cultural space. The results of the study can make a certain contribution to the theory and practice of ethnopedagogical education of students.
Gloss discourse as a gender tool of consumer motivation in the era of digital communications
Authors: Vorozhbitova Aleksandra A. , Bzegezheva Zulima Z. , Buryanova Anastasia A. , Prus Lyudmila V.
Published: August 2021

The purpose of the article is to characterize the glossy magazine discourse (GMD) of the early 21st century as a powerful tool for influencing the recipient in a situation with prevailing digital communication and electronic advertising, as a special discursive process that acts as an explicit tool of globalization.
The phenomenon of creating consumer motivation for predictable purchasing behavior, which is influenced by print and electronic glossy magazine discourse, is analyzed from the standpoint of the Linguistic and Rhetorical (L&R) Paradigm of the Sochi scientific school. The authors suggest an original synergetic methodology combining the methods of linguistics, new rhetoric, pedagogy, psychology and economic management emphasizing the novelty of this discourse in the context of its influence on the formation and transformation of the modern linguistic personality.
It is concluded that this type of discourse, the latest in terms of chronology of the historical process, actualizes the polyethnic sociocultural & educational space of the early 21st century at a new level (on the example of Russia).
It is proved that GMD stimulates transformations in line with the leading trend of the formation of a "planetary linguistic personality" with the value orientations of the "philosophy of glamour".
Folklore and literary continuum in the north caucasian novel of the late xx-th century in the aspect of ethnopedagogy
Authors: Martazanov Arsamak Magomedovich , Martazanova Khanifa Magamedovna , Sarbasheva Alena Mustafaevna
Published: August 2021

The purpose of the work is to comprehend the folklore-literary continuum in the major epic works of national writers. The relevance of the research is due to the scientific and cognitive interest in folklore aesthetics, which determined the dynamics of the development of artistic thought. The novelty of the research is to study the specifics of the inseparable interaction of oral literature and literature within the chronological period of the 1960s-1990s. The main attention is projected on the novel prose of the classics of Ingush and Karachay-Balkar literature Idris Bazorkin (1910-1993) and Alim Teppeev (1937-2010), who made a significant contribution to the development of artistic and intellectual thought of the North Caucasus region. The creative nature of the connection of these aesthetic systems contributes to the philosophical understanding of the historical events recreated by the authors in the life of an ethnic group, the comprehension of national psychology. The appeal to the images of the Ingush and Karachay-Balkar Nart epos, folklore motives is due to the solution of the problems of the spiritual evolution of the literary hero in the context of time. The conducted research allowed us to conclude that the continuity of folklore and literature gives prose works a high aesthetic beginning, the factor of creative evolution contributes to the creation of a national picture of the world, the achievement of artistic expressiveness.
About the Personal Creativity of the Students to Become Teachers
Authors: Stoykov Anton
Published: August 2021

The purpose of this research is to analyze the development of the creative potential of future educators as a mandatory prerequisite for the realization of their future professional activity. For the determination of the level of development of the creative potential of students from this profile, studying in the Master's program "Preschool and Primary School Pedagogy" a Methodology is used to assess the level of creative potential of A. Sharov's personality. This methodology makes it necessary to determine by self-assessment the personal qualities and the frequency of their manifestations, characterizing the level of development of the creative and potential. Analysis of the data obtained shows that creative qualities such as "innovation", "heuristics" and "reformism" have relatively low values, related to qualities such as "purposefulness", "authoritarianism", "intelligence", "practicality". The highest value is the quality "purposefulness", which is a sign of high motivation for professional activity and is a good basis for subsequent development of creative potential. The results obtained in the course of the experimental study give reason to argue that the need for development and inclusion in the educational process with future educators of models for the development of their creative potential is up to date.
CONSTRUCTIVE THINKING AND TEACHING SELF-EFFICACY OF GREEK SPECIAL EDUCATORS: PARALLEL OR CROSSOVER TOPICS?
Authors: Chousou Pinelopi , Simos Thomas , Sakellaropoulou Evdoxia
Published: August 2021

In the present study we investigated the relationship between Epstein’s components of constructive thinking and Teaching Self-Efficacy of Greek special educators. For that purpose, a web questionnaire was sent to special and general education teachers and a research causal model was designed to define relations between variables. The research sample consisted of 214 special educators and general education teachers from the public education system in Greece. Data gathered by utilizing Constructive Thinking Inventory [CTI] and The Teachers’ Sense of Efficacy Scale [TSES] research tools. Data analysis revealed a statistically significant correlation of various components of constructive thinking with Teaching Self-Efficacy. In addition, it has been found that a high degree of constructive thinking increases the Teaching Self-Efficacy of special educators. Finally, we compared the teaching self-efficacy between special and general educators.

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Implementasi Puasa menurut Yesaya 58:1-12 di Wadah Wanita Ester GPdI Ekklesia, Jember
Authors: Sitanggang Murni Hermawaty , Laia Asatinus
Published: August 2021

Since Old Testament times, fasting has been a part of the lifestyle of the Israelites, not least in Isaiah 58. However, this chapter does not contain instructions for implementation but God's stern rebuke of the Israelites' practice of fasting at that time. The Israelites at that time had the mistaken notion that piety only needed to be maintained during fasting and did not involve daily life. They ignored the true meaning of fasting. Therefore, in this paper, the author investigates fasting according to Isaiah 58:1-12 in everyday life. The research was conducted through a qualitative method with a descriptive approach by involving the active fasting participants from the forum of Esther GPdI Ekklesia Women. Data were collected through observation and interviews, which then resulted in the finding that participants had understood that the nature of fasting is not only about piety but also caring for others. They have fulfilled this in their daily life by praying, refraining from oppression, and being just. AbstrakSejak masa Perjanjian Lama, puasa telah menjadi bagian dari gaya hidup umat Israel, tidak terkecuali dalam Yesaya 58. Akan tetapi, pasal ini bukanlah berisi petunjuk pelaksanaan melainkan teguran keras Tuhan terhadap praktik puasa bangsa Israel saat itu. Bangsa Israel saat itu memiliki anggapan keliru bahwa kesalehan hanya perlu dipertahankan saat puasa dan tidak menyangkut kehidupan sehari-hari. Mereka abai akan makna puasa yang sesungguhnya. Oleh sebab itu, dalam tulisan ini penulis menyelidiki bagaimana imple-mentasi puasa menurut Yesaya 58:1-12 tersebut di dalam kehidupan sehari-hari. Penelitian dilakukan melalui metode kualitatif dengan pendekatan deskriptif dengan melibatkan parti-sipan yang aktif berpuasa dari Wadah Wanita Ester GPdI Ekklesia. Data dikumpulkan melalui observasi dan wawancara yang kemudian menghasilkan temuan bahwa partisipan telah memahami bahwa hakikat puasa bukan hanya soal kesalehan melainkan juga mempedulikan sesama. Mereka telah memenuhi hal ini dalam kehidupan sehari-hari dengan cara berdoa, tidak melakukan penindasan, dan bersikap adil.
Antioxidant and phytochemical content of commercial brown rice (Ecobrown) and white rice (Jasmine, Jati Super Special and Manggo Thai) for potential cosmetic rice powder raw materials
Authors: Zakaria Nik Nur Azwanida , Mad Desa Nur Naziha , Zolkopli Mohamad Azrina , Jamal Khairunnisa , Haris Nurul Wahidah , Jaafar Nura’in Nabila , Daud Mohammad Feizal
Published: August 2021

Cosmetic rice powder or “bedak sejuk'' has long being used as part of traditional skincare routine. The powdered rice extract is applied on the face, usually at night and will be rinsed off the next morning to obtain smooth and clear skin complexion. Usually, the regular rice available in one’s kitchen is used to make the cosmetic rice powder but different grades of rice (based on the price) will give different effects to the skin. This study aims to investigate and compare the bioactivities and phytochemical composition of different grades of rice available in the market. The rice sample used in this study was Ecobrown rice, Jasmine White rice, Jati Super Special Tempatan rice and Manggo Thai rice. All rice samples were extracted using distilled water by maceration process. The bioactivities; antioxidant capacity was measured using DPPH assay. Phytochemical content was determined as total phenolic and flavonoid contents (TPC and TFC). High Performance Liquid Chromatography (HPLC) was also used to determine phenolic content expressed as gallic acid equivalent (GAE). The result showed that brown rice had significantly higher antioxidants with IC50 values of 6.4 mg/mL in DPPH assay. The observed activities were corresponding with total phenolic content, where EcoBrown rice has a significantly higher amount of phenolic content (p?0.05) compared to other samples. Meanwhile, almost similar TFC was observed in all rice samples with Jati Super Special. The analysis of phenolic content was correlated with HPLC analysis, where brown rice was shown to have the highest amount of gallic acid content. In conclusion, brown rice can be considered as a better choice to produce “bedak sejuk”.
Unilateral vs. multilateral approaches in US foreign policy: A case study of Iraq and Afghanistan war
Authors: Mahmood Amna , Sherazi Tatheer Zahra , Shahrukh Wajeeh
Published: August 2021

During US war on terror in Iraq and Afghanistan, the Bush administration vindicated its pre-emptive military strikes against Iraq and Afghanistan on the grounds of national security. The strike was carried out under the Bush administration’s National Security Strategy which asserts the right of the U.S to take unilateral military action against rogue states and terrorist organizations in order to prevent or to reduce an assumed attack by such groups or organizations against the United States. However, the action by the administration has been widely criticized as not being in conformity with international law, and United Nations’ Security Council resolutions. It has been investigated in this research paper that the hidden motive behind the attacks on these two countries was not merely the elimination of the terrorist groups and to stop their activities and to destroy the weapons of mass destruction but to capture the oil, gas, and other natural resources in order to sustain the fastest growing economy of the US and western countries. The present study will present a comparative analysis of the two approaches; unilateral and multilateral which were incorporated in U.S foreign policy with the special reference of Iraq and Afghanistan war.
Buracos negros: a derradeira fronteira
Authors: Cardoso Vitor , Duque Francisco
Published: August 2021

Em Setembro de 2015, os dois conjuntos de espelhos mais perfeitos do mundo moveram-se simultaneamente e da mesma forma, apesar de separados por milhares de quilômetros. Chegara ao fim uma das mais longas buscas da história da ciência. Pela primeira vez a humanidade capturara na Terra uma onda gravitacional. Esta onda foi produzida por um par de buracos negros muito antes do nascimento de Einstein e até de qualquer ser humano. O mundo da física prepara-se agora para uma nova era, em que a astronomia gravitacional nos vai desvendar os segredos sobre as entidades mais misteriosas de todas: os buracos negros.
Um Comparativo de Políticas de Fomento ao Empreendedorismo de Portugal e Canadá em Contraste à Intenção Empreendedora de Imigrantes Brasileiros
Authors: Cruz Eduardo , Falcão Roberto , Barbosa Yan
Published: August 2021

O artigo objetiva identificar os fatores prescritores da intenção empreendedora de imigrantes brasileiros nas comunidades de Portugal e Canadá e analisar como as políticas públicas poderiam melhorar o fomento e a assimilação desses imigrantes em suas sociedades. A pesquisa valeu-se de coleta de dados por meio de enquete para identificar variáveis socio-demográficas e de status de visto, relacionados à intenção de empreender, com amostras de 675 respondentes no Canadá e 667 em Portugal. Os dados foram analisados por meio de equação logit, sendo as variáveis preditoras mais relevantes da intenção empreendedora sua idade na chegada, o nível de educação, o tempo no país, o tipo de visto na entrada (de estudante ou turista). Por fim é feito uma discussão sobre as políticas migratórias de incentivo ao empreendedorismo do Canadá e de Portugal, e como poderiam fomentar uma melhor assimilação de empreendedores brasileiros.
Eating Habits and Lifestyle Changes of College Students During COVID-19 Outbreak
Authors: Verdeyen Kathryn , Jones Caroline , Williams Kaywuana , Park Jinkyung
Published: August 2021

The epidemic that was a result of the Coronavirus (Cupples, 2019) began in China towards the end of 2019 and has quickly spread throughout the world. To minimize the spread of the virus and keep it as contained as possible, many countries have required residents to quarantine. This epidemic has been a major concern for students of all ages, especially college students. Students that attend universities have been affected more profoundly due to the close quarters of dorms, fraternities, sororities, and close classroom contact. Due to the contagiousness of the virus and the fact that many who are positive can be asymptomatic hundreds can be affected quickly. The pandemic has forced many students to quarantine themselves. This requires that they not leave their homes, rooms, and apartment for a period of up to 14 days. The purpose of this research was to assess how COVID has affected college students and how it has affected their eating habits and lifestyle habits.
LA FINANCIACIÓN DE LOS MUNICIPIOS VASCOS A TRAVÉS DE SU PARTICIPACIÓN EN LA RECAUDACIÓN POR TRIBUTOS CONCERTADOS.UNA CUESTIÓN COMPETENCIAL NO RESUELTA
Authors: ENDEMAÑO AROSTEGUI JOSÉ MARÍA
Published: August 2021

El Estatuto de Autonomía para el País Vasco y el Concierto Económico
actualmente vigente no determinan si la competencia para regular el régimen
jurídico de la participación de los municipios vascos en la recaudación por
tributos concertados corresponde a los órganos forales de los territorios históricos
o a las comunes de la Comunidad Autónoma. La Ley de Territorios Históricos
(LTH) la atribuye a aquéllos. El legislador autonómico es competente para modificar
la LTH y, con ello, el régimen competencial actual, en el ejercicio de sus competencias
normativas, siempre que respete la imagen históricamente reconocible
de los órganos forales, como titulares de un sustrato básico de facultades implícito
al régimen de concierto económico, de acuerdo con las disposiciones adicionales
primera de la Constitución y tercera del Concierto Económico vigente.

Euskal Herriko Autonomia Estatutuak eta indarrean dagoen Kontzertu
Ekonomikoak ez dute zehazten lurralde historikoetako foru-erakundeei edota
autonomia-erkidegoko organo komunei dagokien euskal udalerriek kontzertatutako
zergen bilketan duten partaidetzaren araubide juridikoa erregulatzeko eskumena.
Lurralde Historikoen Legeak (LHL) foru-erakundeei esleitzen die ahalmen
hori. Legegile autonomikoak LHL aldatzeko eskumena du, eta, beraz, egungo eskumen-
erregimena ere alda dezake, baldin eta Kontzertu Ekonomikoaren erregimenak
inplizituki dituen oinarrizko ahalmenen titular gisa foru-erakundeek historikoki
izan duten figura errespetatzen badu, Konstituzioaren lehen xedapen gehigarriaren
eta indarrean dagoen Kontzertu Ekonomikoaren hirugarren xedapen gehigarriaren
arabera.

The Autonomous Statute of the Basque Country and the Economic
Concert currently in force do not establish whether the competence to regulate the
legal regime of the participation of the Basque municipalities in tax collection of
harmonized taxes belongs to the foral bodies of the Historical Territories or to the
common ones of the Autonomous Community. The Act for Historical Territories
assigns it to the formers. The autonomic legislator has the power to modify the Act
for Historical Territories and therefore the current allocation of powers, by means
of the exercise of its normative competences whenever it respects the historically
recognizable image of the foral bodies as holders of a basic background which
is inherent to the Economic Concert regime in conformity with the first and third
additional provisions of the Constitution and the third one of the current Economic
Concert.