bluuebunny/crossref_metadata_2025 huggingface dataset:
POVEZANOST POTENCIJALA ZA RAZVOD I PSIHOFIZIČKOG ZDRAVLJA ŽENA
Authors: Шакотић-Курбалија Јелена М.
Published: August 2019

U cilju utvrđivanja povezanosti psihofizičkog zdravlja žena sa njihovim potencijalom za razvod, odnosno, sa njihovim razmatranjem razvoda, prikupljeni su podaci na uzorku od 1338 žena, starosti od 21 do 76 godina (AS = 40.07, SD = 9.10), koje su u bračnoj zajednici od jedne do 50 godina (AS = 15.52, SD = 8.85). Potencijal za razvod je meren skraćenom formom Indeksa bračne nestabilnosti (Martial Instability Index: Booth, Johnson & Edwards, 1983), dok je Skala psihofizičkog zdravlja (SPFZ-1: Majstorović, 2011) korišćena za procenu, kako opšteg psihofizičkog zdravlja, tako i njegovih različitih aspekata: poremećaja fizičkog zdravlja, straha i anksioznosti, depresivnih reakcija, umora, i poremećaja socijalnog ponašanja. Rezultati jednofaktorske multivarijantne analize kovarijanse (MANCOVA), pokazuju da su glavni efekti faktora stabilnost/nestabilnost bračnog odnosa, nakon statističkog uklanjanja uticaja roditeljstva, značajni na multivarijantnom nivou, pri čemu ispitanice koje svoj brak procenjuju kao stabilan ostvaruju više skorove na svim dimenzijama psihofizičkog zdravlja u odnosu na ispitanice koje svoj brak procenjuju kao nestabilan. Dobijeni rezultati sugerišu da je, pored razvoda braka, na šta ukazuju brojna dosadašnja istraživanja, i sama bračna nestabilnost značajno povezana sa različitim psihofizičkim simptomima.
RECEPCIJA POEZIJE MIHAJA EMINESKUA U MAĐARSKOJ KNJIŽEVNOSTI S POSEBNIM OSVRTOM NA PREVODILAČKI RAD ŠANDORA KIBEDIJA
Authors: Popovic Virdjinija Aurel , Nemet Ferenc , Puja-Badesku Marina
Published: August 2019

„Moderni klasik književnog romantizma”, kako Emineskua naziva Huba Mozeš, zakoračio je u mađarsku književnost 1885. godine prevodom Jožefa Šandora, koji je na mađarski preveo njegovu pesmu Atît de fragedă. Počev od tada pa sve do danas, veoma je razgranata i bogata mađarska književna recepcija najvećeg i najpopularnijeg rumunskog pesnika. Nakon Jožefa Šandora, njegovu recepciju su svojim prevodima obogaćivali i Lerinc Bran, Geza Seč i Karolj Revai, ali je Emineskuovoj recepciji u mađarskoj književnosti nesumnjivo značajno doprineo Šandor Kibedi, koji je 1934. u Klužu u zasebnoj knjizi prvi put objavio sabrane pesme Mihaila Emineskua (Mihail Eminescu összes költeményei. Cluj–Kolozsvár, 1934). Naravno, i kasnije su  Emineskuovu poeziju  prevodili mađarski književnici (Gere Finta, Zoltan Franjo, Zoltan Jekeli, Lajoš Aprili, Jene Džida, Ferenc Semler), ali već pomenuti Kibedijev prevod kao pionirski poduhvat svakako zaslužuje posebnu pažnju. Ovaj rad osvetljava upravo taj znameniti izdavački poduhvat.
PRÍMENÁ SLOVÁKOV V NIEKTORÝCH SLOVENSKÝCH OSADÁCH BANÁTU
Authors: Makišova Ana , Marčoková Daniela
Published: August 2019

Predmetom nášho výskumu bola neúradná pomenovacia sústava obyvateľov slovenskej národnosti v Banáte. Cieľom nášho výskumu bolo evidovať prímená dospelých obyvateľov mužského pohlavia slovenskej národnosti v troch slovenských osadách v Banáte: v Aradáči, v Jánošíku a v Kovačici. Vo výskume sme uplatnili metódu živej pamäte a materiál sme získavali vlastným terénnym výskumom v rokoch 2018 a 2019. Výsledky nášho výskumu môžeme zhrnúť takto: prímená sú miestne obmedzené, vyjmúc prímen vzťahujúcich sa na remeslá, ktoré sa objavili vo všetkých doteraz skúmaných prostrediach Báčky a Banátu. Dedičné rodinné mená sa v niektorých skúmaných prostrediach vytrácajú a prevahu nadobúdajú individuálne prímená. Okrem toho, že majú pestrú sémantickú motiváciu, živé mená v skúmaných osadách sú prejavom jazykovej kreativity a kultúrnej identity ich občanov. Niektoré prímená svojou jazykovou štruktúrou označujú prítomnosť cudzieho jazyka, preberajú jazykové prvky najčastejšie srbského, menej maďarského jazyka a niekedy nachadzáme i vplyv nemčiny. Pre všetky osady multinacionálnej a multikultúrnej Vojvodiny je príznačné rešpektovanie inonárodných, no zachovávanie vlastných tradícií a jazyka a tak aj tradícií v pomenúvaní.
ANGOL NYELVI ATTITŰDÖK: GYERMEKKORI ANGOL NYELVI SZAVAK, MONDATOK, MONDÓKÁK, RAJZFILMEK
Authors: Kovács Rácz Eleonóra , Pásztor Kicsi Mária
Published: August 2019

A szociolingvisztikai nyelvi attitűdkutatás 788 vajdasági magyar tannyelvű 3. és 4. osztályos középiskolai tanuló angol nyelvi attitűdjébe enged betekintést. A beérkezett válaszok alapján kitérünk az egyes témakörök gimnázium–szakiskola szerinti bemutatására is, mivel adatközlőink e két csoportból valók. Tanulmányunkban az alábbi angol nyelvi attitűdöket ismertetjük: adatközlőink mely angol nyelvi szavakat, mondatokat és mondókákat tanulták meg gyermekkorukban először, valamint annak áttekintésére is kitérünk, hogy mely angol nyelvű rajzfilmeket nézték a vajdasági magyar tannyelvű középiskolások gyermekkorukban. Célunk, hogy a kutatás eredményeit felhasználjuk az ugyancsak általunk elvégzett angol nyelvi attitűdkutatás egyéb eredményeinek bemutatásához, összegzéséhez. A prezentálandó példaanyag alapul szolgálhat a vajdasági magyar ajkú, kiskorú gyermekek angol nyelvi oktatásához.
EMOTIONAL, MENTAL AND PHYSICAL STATES EXPRESSED THROUGH COLOUR CONCEPTS IN ENGLISH AND SERBIAN: A COGNITIVE LINGUISTIC VIEW
Authors: Filipović Kovačević Sonja
Published: August 2019

This paper studies the extended meanings of lexemes with the colour concepts red, pink, blue, green and yellow expressing emotional, mental and physical states in English and Serbian from a cognitive linguistic perspective. The initial hypothesis is that lexemes with these colour concepts express states of the mind and/or the body like being angry, unrealistic or sick, for instance, and that these transferred metaphoric meanings are essentially metonymically grounded. The aims are the following:1. to identify the conceptual metaphors associating concrete colour concepts with the abstract concepts of emotional, mental and physical states, 2. to determine metonymic motivation of colour-related metaphors, 3. to consider the issue of cultural universality and/or diversity. The results of the analysis have shown that the studied colour concepts express meanings associated with different states of the mind and the body, which is presented via conceptual metaphors (e.g. being embarrassed is being red, being unrealistic is seeing pink, etc.). Also, most of these metaphors are based on two metonymies: 1. colour of the skin for the state of the mind/body and 2. an experiential association between a particular colour and people`s psychological reaction. There are more similarities than differences between English and Serbian, which is strong ground for believing that the studied metaphors motivated by metonymies are universal.
IZMEĐU POZORIŠTA I PEDAGOGIJE: POZORIŠNA PEDAGOGIJA I NJENA ULOGA U OBRAZOVNOM PROCESU
Authors: Mitrevski Ana , Kovač Biljana
Published: August 2019

Pozorišna pedagogija (nem. Theaterpädagogik) je samostalna disciplina koja se javlja sedamdesetih godina dvadesetog veka u zemljama nemačkog govornog područja. Nakon mnogobrojnih transformacija koje su pratile njen razvoj, danas predstavlja priznatu interdisciplinarnu oblast, o čemu svedoči sve veći broj naučnih i stručnih publikacija iz pozorišne pedagogije kao i mnoštvo institucija na kojima se ona izučava. U radu se predstavljaju nastanak i razvoj pozorišne pedagogije na nemačkom govornom području, zatim u Rumuniji i u Srbiji, s akcentom na raznovrsnim mogućnostima njene primene u praksi. Pokazalo se da pozorišna pedagogija povoljno utiče na izgradnju i razvoj ličnosti kao i na sticanje ključnih kompetencija. Budući da joj je osnovni cilj estetsko obrazovanje pojedinca, njena uloga u savremenom obrazovanju danas je neosporiva, zbog čega postoji ideja da se uvede kao obavezan školski predmet. Isto tako, u Nemačkoj, Švajcarskoj i Austriji ne postoji veće pozorište koje nema barem jednog pozorišnog pedagoga.
Kontribusi Ilmu Fonetik Dalam Studi Bahasa Arab
Authors: Senen Masyhur Dungcik
Published: August 2019

This description will depict how and what in fact that Ianguage. Ianguage basically  a sign owning meaning based on agreement of user/ wearer,where that sign in the form of sound which”sometime realized into letter form. structured systematically and sistemis. Ianguage used  human being as a means of unruk work along, communicating, identifying x'self and various other function, pursuant to whom, what, to whom, about whom, where, when, old  to what end and with what that Ianguage [is] said. Its nucleus;core, the happening of Ianguage caused by sound

Keyword : Fonetik , Fonemik, Komunikasi, Bahasa Arab.
Toxicity of Granules of Bintaro Leaf Extract (Cerbera odollam Gaertn.) on Armyworm (Spodoptera litura Fab.)
Authors: Sholahuddin Ahmad Habib , Subchan Wachju , Prihatin Jekti
Published: August 2019

Grayak caterpillar is insect pests that become pests of various food crops. Grayak caterpillars cause a decrease in crop productivity and even crop failure if they are not controlled. Pest control using chemical pesticides has many adverse effects on the environment. To minimize the occurrence of environmental damage, then it is used pest control using vegetable insecticides. Bintaro Leaf (Cerbera odollam Gaertn.) is potential as a vegetable insecticide. The purpose of this study was to examine the toxicity of granule from Bintaro leaf extract (C. odollam Gaertn.) on armyworms (S. litura Fab.). This research was a laboratory experimental research using Completely Randomized Design (CRD). Serial concentrations used in this study were 0% (control), 0.5%, 1%, 1.5%, 2%, and 2.5%. The results of this study showed that the granules of Bintaro leaf extract (C. odollam Gaertn.) were effective in causing mortality of armyworms (S. litura Fab.) at 1.5% concentration by 60% and included in toxic category. The value of LC50-48 hour granule from Bintaro leaf extract (C. odollam Gaertn) was 1.41%.

Keywords: Spodoptera litura Fab. , Granula extract of Cerbera odollam Gaertn., Vegetable Insecticide.
Improving Mathayom 2/2 Student Learning Interest in Cell Materials Using Augmented Reality (AR) in Streesmutprakan School, Samut Prakan Province, Thailand
Authors: Apridza Amala Sholeha , Narulita Erlia , Kongsawang Anusorn
Published: August 2019

This study aimed to describe the use of media Augmented Reality (AR) to improve learning interest in Matayom 2/2 class students who are lower secondary grades at Streesmutprakan School. This was a classroom action research (CAR) consisting of two cycles. Each cycle consists of planning stage, acting, observing and reflecting stage. The subjects of this study were all 34 students of Matayom 2/2 class. Data collection techniques included observation, interviews, and documentary analysis. Data analysis techniques used qualitative descriptive analysis. The results showed that students' learning interest in the first cycle was 3.3 with medium criteria, increasing to 4.4 with high criteria in the second cycle. The use of media Augmented Reality (AR) can increase students learning interest in Matayom 2/2 at Streesmutprakan School, Samut Prakan Province, Thailand.

 

Keywords: Augmented Reality, Cell Material, 3D Media, Learning Interest.
PENGARUH AKTIVITAS PERUSAHAAN TERHADAP PROFITABILITAS DAN PELUANG INVESTASI PADA PERUSAHAAN SEKTOR INDUSTRI BARANG KONSUMSI YANG GO-PUBLIC DI INDONESIA
Authors: Jonathan LCA Robin , Militina Theresia
Published: August 2019

This study aims to analyze the effect of company activity that projected in four variables, i.e., Total Asset Turn Over (TATO), Inventory Turn Over (ITO), Fixed Asset Turn Over (FATO), and Working Capital Turn Over (WCTO) on profitability (Return on Asset/ROA) and investment opportunity in the public companies in Indonesia incorporated in the consumer goods industry sector during the period of 2013-2015. The research data were sourced from the company financial reports taken from 37 companies as the research sample that consist of the following industry sub-sectors: food and beverage (17 issuers), cigarettes/tobacco (4 issuers), pharmaceuticals (9 issuers), cosmetics and household needs (4 issuers), and household appliances (3 issuers). Data were analyzed using multiple linear regression and path analysis. The results showed that simultaneously company activity has a significant effect on ROA and ROA significantly mediates the effect of TATO on investment opportunity. However, ITO, FATO, and WCTO have no significant effects on ROA or investment opportunity.
PENGARUH MODAL MANUSIA DAN STRUKTUR ASET TERHADAP RISIKO KREDIT DAN KINERJA KEUANGAN PADA BANK KONVENSIONAL DI INDONESIA
Authors: Roziq Ahmad , Sofianti Septarina Prita Dania , Wasito Wasito , Sulistiyo Agung Budi
Published: August 2019

This study aims to examine the influence of human capital and asset structure on  credit risk and financial performance and the influence of credit risk on financial  performance of conventional banks in Indonesia. This is an explanatory research with the sample consisted of 25 conventional banks in Indonesia during the period of 2013 to 2017. Data were analyzed using PLS. The results showed that: (a) human capital has no significant influence on credit risk of the conventional banks in Indonesia; (b) human capital has no significant influence on the financial performance of conventional banks in Indonesia, (c) credit risk has significant influence on the financial performance of conventional banks in Indonesia, (d) asset structure has significant influence on the credit risk  of  conventional banks in Indonesia, and (e) asset structure  has no significant influence on the financial performance of  conventional banks in Indonesia.
PENGARUH DIMENSI KUALITAS LAYANAN TERHADAP CUSTOMER DELIGHT MELALUI CUSTOMER SATISFACTION
Authors: Putri Husni Indrawati Wijaya
Published: August 2019

The objective of this research is to analyze the influence of service quality dimensions which consist of tangibles; reliability; responsiveness; assurance; and empathy on customer delight through customer satisfaction. The research sample was the students of the Faculty of Economics and Business, Study Program of Management, University of Wijaya Kusuma Surabaya batch of 2016/2017 that consisted of 90 respondents. The data analysis technique used was path analysis. The results showed that the dimensions of service quality, i.e., tangibles, reliability, responsiveness, assurance, and empathy affect customer delight as mediated by customer satisfaction.
INTERPRETASI KEPERCAYAAN DEBITUR KKM CENTRAL SANTOSA FINANCE CABANG SURABAYA
Authors: Izaak Wilma Cordelia , Rini Hesty Prima
Published: August 2019

The purpose of this study is to analyze and interpret the effect of perceived quality and perceived value on consumer satisfaction and loyalty. The research sample was taken using a purposive sampling technique with the sample consisting of 67 debtors of motorbike ownership credit at the Central Santosa Finance Surabaya. The research data were analyzed using Partial Least Square (PLS) method. The results showed that perceived quality had a significant positive effect on loyalty through satisfaction, and perceived value had a significant positive effect on loyalty, both directly and indirectly through satisfaction. However, perceived quality did not have a direct effect on loyalty. These results implied that the company should continuously improve its service quality to maintain customer trust, satisfaction, and loyalty.

Keywords: loyalty, perceived quality, perceived value, satisfaction.
Studi Literatur: Model Pembelajaran Quantum Teaching Dalam Meningkatkan Keberanian Berbicara Siswa Menggunakan Media Realia
Authors: Adikalan Thoriq Hasan
Published: August 2019

One of the reasons for the low learning outcomes is that the learning method used by the teacher does not involve student activity and also the lack of care from the teacher to provide media in learning. The courage to speak a student is very important and needed in a class discussion, because with a student daring to speak in front of the class he has been found as an active student. The purpose of this article is to discuss the application of realia media in increasing the courage to speak students during learning or class discussion so as to increase student activity. Realia media is an object that can be seen, heard or experienced by students so as to provide experience directly to them. Quantum Teaching is an effective and fun and not boring learning model. Quantum Teaching learning steps are known as TANDUR: (1) Grow (2) Natural (3) Rename (4) Demonstration (5) Repeat and (6) Celebrate. Relevant research results show that Media Realia is able to increase student activity in asking, discussing, and expressing their opinions.

 

Keyword: Quantum Teaching, Media Realia, Speak.
Demonstration Learning Berbasis Video Pembelajaran dalam Meningkatkan Hasil Belajar IPA Siswa SMP
Authors: Baity Wardah Laily Nur
Published: August 2019

Education is guidance carried out by educators consciously on the physical and spiritual development of students as an effort to mature a person through guidance and training. Education in Indonesia continues to grow in line with the times. So that a teacher is required to provide material not only using the lecture method but using other learning methods. The purpose of this study is to find out about improving student learning outcomes by using a demonstration learning method based on learning videos. With the use of student learning videos it is easier to understand the material being taught so that it can link material taught with natural phenomena. In addition students do not feel bored when they are in class and have a high curiosity so students actively ask in class. The use of video learning also improves student learning outcomes.

 

Kata Kunci: demonstration method, learning achievement and learning video
Penerapan Model Pembelajaran IPA Dengan Menggunakan Metode Keterampilan Berfikir Kreatif Siswa Dan Pemahaman Konsep IPA Siswa SMP
Authors: Yolanda Silvia Bella
Published: August 2019

Abstrak: Kurang terlibatnya seorang peserta didik dalam suatu proses pembelajaran atau dalam kata lain yang bersifat eacher center, hal tersebuat dapat menyebabkan seorang anak didik atau ppeserta didik mengalami rendahnya daya untuk berpikir kreatif, baik dari segi intelektual, konsentrasi, percaya diri dan kepribadian. Serta didalam suatu proses pembelajaran terdapat masalah mengenai kurangnya atau rendahnya pemahaman siswa terhadap konsep  mata pelajaran IPA. Penelitian ini dibuat guna untuk meningkatkan penerapan model dalam pembelajaran IPA siswa SMP yang menggunakan metode keterampilan berfikir kreatif siswa dan pemahaman konsep IPA, serta melihat bahwa disekolah sudah menerapkan model pembelajaran terseburt atau belum.  Dalam penelitian ini menggunakan metode analisis deskriptif dengan pengambilan data melalui proses wawancara tes mengenai materi pembelajaran dengan beberapa siswa SMP kelas IX. Sampel penelitian ini diambil dari SMP Negeri 3 Rambipuji dengan menggunakan 25 siswa. Dari hasil penelitian yang telah dilakukan melalui tes wawancara dapat dinyatakan bahwasanya 70% dari siswa SMP Negeri 3 Rambipuji sudah menjawab dengan baik dan dalam hal berfikir kreatif dan pemahaman konsepnya sudah baik. Sehingga dapat dinyatakan bahwasanya penerapan model pembelajaran IPA dengan menggunakan metode berfikir kreatif dan metode pemahaman konsep sangat penting dan berpengaruh dalam kegiatan pembelajaran.

 

Kata kunci: Keterampilan Berfikir Kreatif Siswa, Pemahaman Konsep IPA
Bridging the Gaps: Local Government and Nonprofit Collaborations
Authors: Collins Todd , Gerlach John David
Published: August 2019

Local governments and nonprofit organizations often struggle to provide quality services to their residents and clients. One potential way for these organizations to overcome obstacles in service provision is to engage in joint programming and service delivery. In this study, we use original survey data collected from local government and nonprofit managers in the state of North Carolina to examine recent trends in collaboration between these sectors. Specifically, we explore the perceptions of these managers concerning the types of collaborations that work best, the types of collaborations that are least successful, and the factors that foster or hinder cooperation. We also explore the perceptions that these managers have about the other. We hypothesize that positive perceptions of the other sector, greater access to resources, operating in a more urbanized environment, and participation in past positive cross-sector collaboration experiences will all lead to increased collaboration between local governments and nonprofits. We find, however, that although an organization’s resources and managerial perceptions of the other sector do influence collaboration, having participated in a past successful collaboration does not necessarily lead to an increase in future partnerships.
FAKTOR UTAMA PEMILIHAN LOKASI KAFE DI KOTA SURAKARTA
Authors: Khoirul Muhammad , Yudana Galing , Rahayu Paramita
Published: August 2019

Kafe yang merupakan salah satu bentuk dari “third place” saat ini telah mengalami perkembangan yang sangat signifikan di kota-kota besar termasuk di Kota Surakarta. Lokasi kafe di Kota Surakarta tersebar di sekitar kawasan perdagangan dan kawasan permukiman. Keberadaan beberapa kafe di kawasan permukiman terkadang memberikan beberapa permasalahan, seperti kemacetan dan kebisingan dari aktivitas kafe. Oleh karena itu, penelitian ini bertujuan untuk menentukan faktor utama dalam pemilihan lokasi kafe di Kota Surakarta. Faktor utama pemilihan kafe di Kota Surakarta didapatkan dari analisis faktor yang dilakukan terhadap penilaian pemilik kafe di Kota Surakarta terhadap faktor-faktor pemilihan lokasi saat akan mendirikan usaha kafe menggunakan skala sikap likert. Berdasarkan hasil analisis faktor didapatkan 4 kelompok faktor yang bisa merangkum 14 faktor pemilihan lokasi di awal. Faktor pemilihan lokasi kafe di Kota Surakarta ditentukan oleh fleksibilitas lokasi, kesesuaian lokasi, dukungan lingkungan sekitar, dan faktor tambahan.
Comparative Petrological Studies of 1962 and 1988–1989 Eruptions of Tokachidake Volcano, Japan: A Case Study for Understanding the Relationship Between Eruption Style and Magma Processes
Authors: Nakagawa Mitsuhiro , Matsumoto Akiko , Kobayashi Kyohei , Wada Keiji ,   Department of Natural History Sciences, Graduate School of Science, Hokkaido University N10W8 Kita-ku, Sapporo, Hokkaido 060-0810, Japan,   Koken Engineering Co., Ltd., Sapporo, Japan,   Earth Science Laboratory, Hokkaido University of Education, Asahikawa, Japan
Published: August 2019

Repeated magmatic eruptions of Tokachidake volcano have caused severe volcanic disasters on three occasions during the 20th century. To prepare for the next eruptive activity, understanding the structure of the magma plumbing system by using petrological analysis of juvenile materials is crucial. Here, we perform petrological analysis of juvenile materials to investigate the difference between two contrasting eruptions in 1962 and 1988–1989, respectively. All these juvenile materials are composed of mafic andesite, which were formed by mixing of olivine-bearing basaltic and pyroxene andesitic magmas. The compositional zonations of olivine phenocrysts in all of these rocks suggest that the injection of the basaltic magma into the andesitic magma occurred several months prior to the 1962 eruption and about six months before the 1988–1989 eruption. In the case of the 1962 activity, the mixed magma rapidly ascended without stagnation from the magma chamber and erupted as a sub-Plinian type. However, the juvenile materials of the 1988–1989 eruptions show distinct petrological features such as higher crystallinity of the matrix, orthopyroxene reaction rims around the olivine, and overgrowth mantle zones around Ti-magnetite phenocrysts. These features suggest that the mixed magma ascended slowly and possibly stagnated at shallower levels prior to eruption. The stagnated magma became a cap rock of the vent system and caused a series of Vulcanian eruptions. These distinct modes of magma ascent can be explained by differences in the magma supply rate. In the case of the 1962 eruption, the volume of magma that erupted in a period of less than 24 h was 7.1 × 107 m3. On the contrary, 23 explosions occurred over three months of the 1988–1989 activity and generated 1 × 105 m3 of ejecta including juvenile and non-juvenile materials. These large eruption rate differences can be attributed to the distinct ascent rates of the magma between the two eruptive activities.
Evaluation of the effectiveness and tolerance of tetracosactide in the treatment of post-dural puncture headaches (ESYBRECHE): A study protocol for a randomized controlled trial
Authors: Depaulis Celia , Steer Nadia , Chassard Dominique , Aubrun Frederic
Published: August 2019

Background

Post-dural puncture headache (PDPH) is one of the most common complications of neuraxial anesthesia. It limits patients’ general activity and increases hospital length of stay and use of care. It is particularly disabling during the postpartum period, when mothers have to take care of their child. Epidural blood patch is the standard treatment of PDPH. However, it is an invasive procedure that may result in rare but serious complications. Recent evidence suggests the effectiveness of adrenocorticotropic hormone (ACTH) in the management of PDPH. The aim of this study is to assess the efficacy and safety of tetracosactide (Synacthen®), a synthetic analogue of ACTH, in the treatment of PDPH in patients who received neuraxial anesthesia during labor.

Method

This is a randomized, double-blinded, placebo-controlled, parallel-arm trial, performed in two French university hospitals. Eligible patients are those suffering from postpartum PDPH, who are randomized to receive either 1 mg of tetracosactide intravenously over 20 min, or 0.9% saline (placebo). The primary endpoint of the study is the rate of epidural blood patch within a 15-day follow-up period. Duration of headache, intensity of pain, reduction of general activity, increase of hospital length of stay, adverse events, analgesic use (type and duration), and number of blood patches per patient in each group are recorded.

Discussion

We expect a decrease in the use of epidural blood patch in those who receive tetracosactide, thus indicating a decrease in PDPH symptoms in these patients. This will define the therapeutic success of tetracosactide and the possibility to use this treatment as a noninvasive alternative to blood patch in the treatment of PDPH.
Exploring the utility of the Pain Attitudes and Beliefs Scale with general practitioners and physiotherapists in the context of osteoarthritis: a cross-sectional observational study
Authors: O'Brien Daniel William , Clair Valerie Wright St , Siegert Richard , Bassett Sandra
Published: August 2019

Background

Conservative treatments for hip and knee joint osteoarthritis are underused despite the known benefits. Adherence to conservative treatments is poor and affected by people’s health, illness and treatment beliefs. Clinicians’ beliefs can also affect the advice and education given to patients. Few studies have explored general practitioners’ (GPs; primary care physicians) and physiotherapists’ osteoarthritis-related health, illness and treatment beliefs. In addition, limited questionnaires are available to explore this phenomenon. This study aimed to identify if GPs and physiotherapists had beliefs about osteoarthritis that fit better with biomedical or biopsychosocial models, and explore the utility of the Pain Attitudes and Beliefs Scale for Physiotherapists (PABS-PT) adapted for osteoarthritis.

Methods

This study used a cross-sectional observational design. Data were collected anonymously from GPs and physiotherapists using an online survey. The survey included a study-specific demographic and occupational characteristics questionnaire and the PABS-PT questionnaire adapted for osteoarthritis. All data were analysed using descriptive statistics. PABS-PT data also underwent principal factor analysis.

Results

In total, 295 clinicians (87 GPs, 208 physiotherapists) participated in this study. The principal factor analysis identified two factors or subscales (biomedical and behavioural), with Cronbach’s alphas of 0.84 and 0.44, respectively. Participants scored higher on the behavioural (3.85) than the biomedical (2.78) beliefs subscale.

Conclusions

The results suggest clinicians’ osteoarthritis beliefs are broadly more behavioural (biopsychosocial) than biomedical in orientation. However, the poor internal consistency of the behavioural subscale suggests the PABS-PT is not suitable for adaptation for osteoarthritis.
Identification of Transcription Factors related to Diabetic Tubulointerstitial Injury
Authors: Liu Jialu , Duan Guangzhong , Yang Wenxia , Zhang Shumin , Liu Fuyou , Peng Youming , Sun Lin , Liu Yu , Xiao Li
Published: August 2019

Background: Diabetic nephropathy (DN) is a main cause of chronic renal failure. Despite decades of extensive study, the molecular mechanisms underlying diabetic tubulointerstitial injury remain unclear. We aim to identify key transcription factor genes involved in diabetic tubulointerstitial injury.
Methods: A microarray dataset (GSE30122) from Gene Expression Omnibus (GEO) was downloaded. A total of 38 transcription factor genes based on 166 differentially expressed genes(DEGs) were identified by UCSC_TFBS.
Results: The regulatory network showed connections between top 10 transcription factors and their target DEGs. Gene Ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of targeted DEGs indicated that extracellular space, extracellular exosome, cell surface and complement and coagulation cascades were most significantly enriched. Utilizing Nephroseq v5 online platform, the mRNA expression pattern analysis of transcription factor genes demonstrated that mRNA expression of CDC5, CEBPA, FAC1, HFH1, IRF1, NFE2 and TGIF1 increased in renal tubulointerstium of DN patients compared with normal controls while that of CEBPB and FOXO4 decreased in renal tubulointerstium of DN patients compared with normal controls.Correlation analysis between mRNA expression of transcription factor genes in renal tubulointerstium and clinical features showed that AP1, BACH1, CDC5, FAC1, FOXD1, FOXJ2, FOXO1, FOXO4, HFH1, IRF1, POU3F2, SOX5, SOX9, RSRFC4, S8 and TGIF1 may be related to diabetic tubulointerstitial injury.
Conclusions: 1)CDC5, FAC1, FOXO4, HFH1, IRF1 and TGIF1 may be key transcription factor genes. 2)Transcription factors involved in diabetic tubulointerstitial injury may become prospective targets for diagnosis and treatment of DN.
Application of subjective and objective tools for the evaluation of the articulatory organs among patients with amyotrophic lateral sclerosis
Authors: Pawlukowska Wioletta , Baumert Bartłomiej , Gołąb-Janowska Monika , Meller Agnieszka , Machowska-Sempruch Karolina , Wełnicka Agnieszka , Paczkowska Edyta , Rotter Iwona , Machaliński Bogusław , Nowacki Przemysław
Published: August 2019

Introduction

Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease of a rapid course. In 25% of ALS sufferers, speech disorders occur as prodromal symptoms of the disease. Impaired communication affects physical health and has a negative impact on mental and emotional condition. In this study, we assessed which domains of speech are particularly affected in ALS. Subsequently, we estimated possible correlations between the ALS patients’ subjective perception of their speech quality and an objective assessment of the speech organs carried out by an expert.

Methods

The study group consisted of 63 patients with sporadic ALS. The patients were examined for articulatory functions by means of Voice Handicap Index (VHI) and the Frenchay Dysarthria Assessment (FDA).

Results

On the basis of the VHI scores, the entire cohort was divided into 2 groups: group I (40 subjects) with mild speech impairment, and group II (23 subjects) displaying moderate and profound speech deficits. The deficits were observed more frequently in men (60.31%). In an early phase of ALS, changes were typically reported in the tongue, lips and soft palate. The FDA and VHI-based measurements revealed a high, positive correlation between the objective and subjective evaluation of articulation quality.

Conclusion

Deterioration of the articulatory organs resulted in the reduction of social, physical and emotional functioning. The highly positive correlation between the VHI and FDA scales seems to indicate that the VHI questionnaire may be a reliable, self-contained tool for monitoring the course and progression of speech disorders in ALS.
HIERARCHICAL CLUSTERING OF SEISMIC ACTIVITY LOCAL TERRITORIES GLOBE
Authors: Tiutiunyk Vadym , Kalugin Vladimir , Pysklakova Olha , Yaschenko Olexandr , Agazade Tural
Published: August 2019

In article, the interrelation between energy parameters of Globe moving in a system Sun-Earth-Moon has been established. It includes features of a seasonal energy condition of an internal core of Earth and the key energy parameters of tectonic activity of seismically dangerous local territories of the planet. These parameters have been systematized by means of a clustering method hierarchical. The mechanism of energy influence of core Earth fluctuations on variations of axial rotation speed of the Globe and level of seismic activity has been grounded. The phenomenon of a periodic oscillation of planet condition seismic and effect of asymmetric distribution of the emergency situations (ES) of tectonic origin on the Earth's surface has been established. For the first time, ranging of the seismically fissile local territories of the Globe in the parameters determining the level of seismic activity and ranges of magnitudes was carried out. Based on these results the effect of division of the seismically fissile local territories into three main clusters that characterized by rather high, average and low degrees of seismic activity was established. Join of the ranged seismically fissile local territories of the Globe permit to establish zones with various degree of seismic activity along the section of various geophysical plates. The results received in article are a basis for further carrying out complex assessment of interrelations between key parameters of moving Globe in a system Sun-Earth-Moon and key parameters of tectonic danger of the seismically fissile local territories of Earth. It is base for further increase in effectiveness of monitoring of origin tectonic emergency by development of neural network prognostic models.
ESTIMATION OF THE OVERALL TAX BURDEN ON THE ECONOMY IN UKRAINE
Authors: Martynenko Valentyna
Published: August 2019

The estimation of the tax burden is important, since, on the one hand, its results reflect the tax system efficiency, and, on the other hands, the level of income redistribution in the national economy. The estimation of the general tax burden level on the national economy of Ukraine should be realized through the development of forecast scenarios, based on economic and mathematical modelling. The economists have not yet sufficiently worked out the problems of the predictive assessment of the tax system efficiency through the introduction of a scenario approach, economic-mathematical modelling and extrapolation of dynamics series. It is necessary to evaluate and to develop scenarios for forecasting the level of the overall tax burden on the national economy of Ukraine. The modelling of the influence of GDP dynamics on the volume of tax revenues and a unified social tax is implemented. The method of calculating the level of the overall tax burden on the national economy is proposed. The scenarios for forecasting the total tax burden on the Ukrainian economy have been developed. It is proved that in Ukraine, by the end of 2017, one third of the revenues in the national economy is redistributed through the fiscal system, while in 2004 the tax burden made only a quarter of GDP. Thus, it is established, that over the next 5 years, the overall tax burden on the national economy will increase (growth may range from +0.9 to +4 %).
DETERMINATION OF MOLECULAR GENETIC MARKERS IN PROGNOSIS OF THE EFFECTIVENESS OF TREATMENT OF MALIGNANT INTRACEREBRAL BRAIN TUMORS
Authors: Glavatskyi Oleksandr , Vasileva Irina , Galanta Olena , Khmelnytskyi Hennadii , Shuba Irina , Kardash Konstantin , Zemskova Oksana
Published: August 2019

Intracerebral malignant brain tumors remain one of the most complex problems of neuro-oncology. Today, promising results of the use of targeted drugs have been received, which determine the important diagnostic and predictive value of molecular genetic markers of glial and metastatic brain tumors.

Aim: The study of the prevalence of MGMT (O6-methylguanine-DNA methyltransferase) and PTEN (phosphatase and tensin homologue deleted on chromosome 10) gene expression by real time polymerase chain reaction in tumor tissue of gliomas and brain metastases.

Materials and methods: From thirty patients were received tumor material (29 cases of glioma III-IV degree of anaplasia and one case of metastatic brain lesion of adenocarcinoma). The normalized expression of MGMT and PTEN genes was determined by real-time polymerase chain reaction.

Results: In all 30 (100 %) patients with tumor fragments, we determined normalized expression of MGMT and PTEN genes. In most cases, 53 % of the observations (16 out of 30 patients) showed a low normalized expression of MGMT gene (<40 c. u.) and a low normalized PTEN expression rate of 73 % (22 out of 30 patients) (<40 c. u.). The average expression level of the MGMT gene in the range from 40 to 100 c. u. (6/20 % of patients) was considered prognostic favourable for the response to temozolomide chemotherapy.

Conclusions: The study of MGMT gene expression, a chemotherapy marker for temozolomide, indicates a trend toward correlation between expression levels and therapeutic efficacy. The study of the expression of the PTEN gene, the blocker of the PI3K / AKT signal pathway, indicates a different degree of expression of this enzyme in the tumour samples studied. The predictive value of the indicator for target therapy is appropriate in comparison with the EGFR mutation. Further profound analysis of the results is required with increasing number of sampling and observation period.
MUSCLE SPASTICITY AND ITS INTERACTION WITH MYOFASCIAL SYSTEM OF CHILDREN WITH CENTRAL PARESIS
Authors: Moga Nikolay
Published: August 2019

Traditionally, the problem of muscle spasticity was considered by experts as a kind of local problem associated with the inhibition or traumatisation of the central motor neuron in a certain part of its path. According to this approach, only the first stage of the causal relationship of the two systems was reflected: the nervous and the muscular systems. In the following, intrasystem relations of the muscle and muscle complex appeared according to the type of harmonization or destructivization of the activity of this system. To resolve this problematic situation, the article examines the original theory of Thomas V. Myers about “anatomical trains” or “myofascial meridians” as an integral musculoskeletal system of the human body, which forms the basis of its anatomy and motor activity. Key ideas of tensegrity as a structure of balanced compression-tension of the musculoskeletal system are identified, and it is necessary to rush to the targets, carrying out the correction of motor disorders of the tender age children with paresis of central type by means of physical education. For deeper understanding of the activities of these mechanisms of children myofascial status harmonization, the main myofascial lines were briefly characterized: surface back line, surface frontal line, lateral line, spiral line, arm lines. On this basis, working hypothesis was formulated as for using the holistic myofascial system capabilities of the child’s body to correct both the tonic state of individual spastic muscles and to improve the general children motor status. To check the formulated hypothesis, the directions of the implementation of correctively directed physical education of tender age children with central paresis of different localization levels were indicated. An attempt was made to use the basic knowledge of the myofascial meridians functioning to increase the efficiency of diagnosing the state of musculoskeletal formations of children with spastic paresis, developing strategies and tactics for correcting their tonic state, methods and techniques for adjusting the balance of compression and tension of these structures to improve children motor activity and to improve the efficiency of their basic motor regimes mastering. There was made a fundamental conclusion that the correctional work by means of physical education should be preceded by preparatory work aimed at normalization of the whole myofascial system of a child with a spastic type of movement disorders, which can be carried out using purely medical techniques and the techniques based on the means of children physical education. Prospects of the scientific and practical development of the problem indicated in this article are highlighted separately.
Optimum Nitrogen Rates for Maize and Wheat in North Carolina
Authors: Austin Robert , Osmond Deanna , Shelton Shelby
Published: August 2019

Nitrogen decision making and the selection of the “right” N rate in wheat (Triticum aestivum L.) and maize (Zea mays L.) are difficult due to complex interactions in the N cycle with weather, management, and genetics. An adaptive management approach utilizing farmer networks and participatory learning was established to refine N rate decisions. On‐farm trials were established to reflect grower N rate with additional treatments of ±25% N. In 79 site‐years of wheat, N−25%, Nstd, and N+25% rate treatments were best in 37, 35, and 28% of the trials, respectively. In 100 site‐years of maize, N−25%, Nstd, and N+25% rate treatments were best in 58, 30, and 12% of the trials, respectively. Grower’s selected N rates in wheat were similar to recommendations from the North Carolina Realistic Yield Expectation (RYE) database while maize N rates were an average 48 kg ha−1 higher; however, N−25% rates, which were best 58% of the time, were similar to RYE N rate. Doppler‐based estimates of total precipitation from the National Weather Center explained 90% of the average maize yield variability. However, site‐yield was independent of location, N rate, and total precipitation. Measures of performance (N factor productivity and N balance) varied with achieved yields but indicate most growers apply N adequate to maintain organic N lost through mineralization. Results suggest that improved approaches to N rate selection and N efficiency will likely require in‐season adjustments to yield‐based N rates that incorporate local management and environmental conditions throughout the growing season.

Core Ideas

Yield level and response is independent of location, N rate, and total precipitation.

Doppler‐based rainfall estimates help explain seasonal trends in yield.

Growers often select N rates greater than recommended for maize but not wheat.
Asymbiotic Nitrogen Fixation is Greater in Soils under Long‐Term No‐Till Versus Conventional Tillage
Authors: Franzen David W. , Inglett Patrick , Gasch Caley K.
Published: August 2019

A series of N‐rate experiments previously conducted in spring wheat, corn, and sunflower in North Dakota indicated that less N was required when fields were in six years or more continuous no‐till compared to conventional till. The objective of this study was to determine whether part of the reason for the decreased requirement for N was the greater activity of asymbiotic N‐fixing organisms. Twelve paired‐samplings were conducted in 2018. A surface 0‐ to 5‐cm deep sample was obtained in a long‐term no‐till field directly across the fence or road from a similar soil in conventional till. Samples were incubated in an acetylene‐reduction procedure to estimate N fixation rate. Ten of twelve paired samplings had greater asymbiotic N fixation compared to the conventional till counterpart. This indicates that long‐term no‐till soils support greater N production from soil microorganisms than conventional till soils, which would result in lower input costs to no‐till farmers.

Core Ideas

Microbial communities are different between conventional till and no‐till managed soils.

Asymbiotic N‐fixation was greater in farmer‐managed no‐till than neighboring conventional till.

N recommendations in long‐term continuous no‐till should be separate from conventional till N recommendations.
Effective water quantity of multi-source water recharging aquifers in Yufuhe River based on groundwater and surface water semi-coupled modelling
Authors: Li Wenliang , Sun Qing , Wang Weiping , Qu Shisong , Zhang Zhengxian , Xu Qiaoyi
Published: August 2019

With rapid urbanisation, a karst water recharge area of the Jinan spring catchment was damaged. Thus, managed aquifer recharge projects were built in the western Jinan spring catchment to protect the water supply of the spring. Yufuhe River was selected as the study area to compute the effective recharge rate into karst aquifers. This strong seepage zone has a large gradient and undergoes a specific hydrogeological condition in which two strata of a gravel layer and limestone change to three strata of gravel, impermeable clay shale and limestone at the open window of the karst aquifers. A hydraulic model called HEC-RAS was applied to simulate the river stage, and a numerical groundwater model called HYDRUS-3D was adopted to simulate the groundwater mound dynamics and estimate river flow seepage into the aquifers. The effective recharge rates are 64.9%, 65.2% and 68.1% when the buried depths of groundwater are 40, 30 and 25 m. An analysis of the electric conductivity, water table, temperature and water volume data found an effective recharge rate of 68.3%. Results of field monitoring confirmed the accuracy of the numerical simulation and showed that most of the recharged water in the study reach can be effectively recharged into the karst aquifers.
Particular internal recirculation frequency scope for enhancing denitrifying phosphorus removal in an oxidation ditch
Authors: Wang Shao Po , Yu Jing Jie , Su Fan Kai , Gao Fu , Sun Li Ping
Published: August 2019

This study investigated the influence of the unique internal recirculation characteristics of an oxidation ditch (OD) system, namely, the internal recirculation frequency (IRF) on denitrifying phosphorus removal (DNPR). The ratios of denitrifying polyphosphate-accumulating organisms (DPAOs) to polyphosphate-accumulating organisms (PAOs) under different IRF conditions were measured using a batch experiment. On this basis, the variation of nutrient transformations were studied using the IRF changes by the mass balance method. The results showed that for the OD system that had an anaerobic zone upstream from the circular corridor and set anoxic and aerobic zones along the circular corridor, when the IRF was between 3.4 h−1 and 7.5 h−1, the DPAOs/PAOs ratio reached about 50%. Approximately 20% of the total phosphorus (TP) was removed and over 11% of the total nitrogen (TN) was transformed into nitrogen gas by the DNPR process, and meanwhile the total removal efficiencies of the TP and TN were over 93% and 80%. When the IRF was greater than 11.5 h−1, the TN removal efficiency decreased significantly, and this was not conducive to simultaneous nitrogen and phosphorus removal. The results indicated that OD process would possess a better DNPR potential if the IRF was controlled within the proper scope.