Condition assessment of infants born to mothers with urinary diseases
Authors:   SI ", Melenchuk L.M. ,   Institute of Hereditary Pathology of National Academy of Medical Sciences of Ukraine",   , Lviv, Ukraine, Shargorodska Y.B. ,   SI "Institute of Hereditary Pathology of National Academy of Medical Sciences of Ukraine", Lviv, Ukraine
Published: July 2021

The research aim is to study factors of perinatal complications among women with diseases of the urinary system on the basis of retrospective analysis of their newborns' condition. Materials and Methods. A total of 160 women with urinary diseases were selected for the study in Lviv Regional Clinical Hospital from 2014 to 2017. We studied the development of infants born to women with a clinical diagnosis of "Diseases of the urinary system". The newborns' gestational age at birth, anthropometric indicators, and condition assessment on the Apgar scale were analyzed. The obtained indicators were compared with similar parameters in the control group of healthy women that had given birth to live children in the same maternity department during the same period of time. Results and Discussion. We analyzed the condition of infants born to 130 women with urinary diseases. 68 of them were hospitalized with pyelonephritis, and 62 - with chronic pyelonephritis. The control group included 30 healthy female patients. The gestation age analysis showed that the number of preterm babies was higher in the group of infants born to mothers with acute pyelonephritis - 13 cases (10.0%) and even much higher in the group of mothers with chronic pyelonephritis - 25 cases (19.2%). These results were compared with the data obtained from the control group in which 30 full-term babies (100.0%) were born, (p <0.05). In the group of women with acute pyelonephritis, the majority of infants were born with the body weight more than 2500.0 g - 55 cases (42.3%), and 13 (10.0%) infants with the birth weight less than 2500.0 g. The mothers with chronic pyelonephritis gave birth to infants with the body weight less than 2500.0 g in 37 cases studied (28.5%). There was also a significant number of low birth weight newborns in this group - 25 cases (19.2%). In the control group, all 30 babies (100.0%) were born healthy weighing over 2500.0 g. Infants receiving less than 7 points on the Apgar scale were born to women with acute pyelonephritis in 15 cases (11.5%) and to mothers with chronic pyelonephritis in 25 cases (19.2%). In the group of healthy women, all newborns' condition was satisfactory. Conclusions. Women with urinary pathology are confirmed to be at risk of perinatal complications. The research has revealed the significant differences in gestational age, birth weight, and the Apgar score among infants born to women in the main and control groups (p<0.05). The infants whose mothers suffered from urinary pathology were often born prematurely: 13 (10.0%) - to mothers with acute pyelonephritis and 25 (19.2%) - to mothers with chronic pyelonephritis. At the same time the infants in the control group were born healthy (100.0%). Therefore, women with urinary pathology are recommended to be included in the "risk group" for perinatal complications.