bluuebunny/crossref_metadata_2025 huggingface dataset:
ETHNOGRAPHIC COLLECTION OF THE CHAUNSKY LOCAL HISTORY MUSEUM (TOWN OF PEVEK, CHUKOTKA)
Authors: Samoylova Natalia
Published: January 2025

The article examines the ethnographic collection of the Chaunsky Local History Museum, located in the town of Pevek, Chukotka autonomous district. The author, relying on the methodology of the Russian Ethnographic Museum and scientific literature, provides a classification of objects of applied art, everyday life and ethnography of northern peoples, gives a brief description of their things, describes the technologies of their manufacture. The formation of the ethnographic collection began with the receipt of items from a folk museum. The ethnographic collection of the museum consists of unique items of traditional Chukchi culture in the amount of 456 storage units. The geography of the places of receiving ethnographic items is concentrated in the vicinity of the Chaunsky district. Some ethnographic topics are represented by decorative and applied items and works of bone carving art. In general, the collection reflects the culture of primary production of the Chukchi, their livelihood methods, and reveals socio-normative relations of the northern peoples. However, the collection does not have enough items for a complete reconstruction of ethnographic topics; no traditional culture of the ethnic groups living in the region is represented; no history of collection is presented; and the names of the collectors require clarification. Based on the results of the study, the composition of the collection is analyzed, problematic issues of acquisition and attribution are revealed, and recommendations for promising areas of work of the museum with ethnographic items are given.
PALAEONTOLOGISTS FROM MOSCOW UNIVERSITY IN THE SCIENTIFIC AND ARTISTIC EXPOSITION AT THE EARTH SCIENCE MUSEUM OF MSU
Authors: Moloshnikov Sergey , Valentina Nazarova
Published: January 2025

The gallery of artistic portraits of outstanding Russian and foreign naturalists, consisting of sculptures and paintings, occupies an important place in the exposition of the Earth Science Museum at Moscow State University. The 270th anniversary of the Moscow State University named after Lomonosov and 75th anniversary of its Earth Science Museum is an occasion to turn to the activities of scientists directly related to Moscow University. The portraits of paleontologists of the 19th - first half of the 20th century, which were at the beginning of the science of fossil organisms at Moscow University, are shown in the museum halls. They have contributed to the development of this science, as well as museology at the university, and laid the foundation for modern research and teaching paleontological courses. Among them are the learners of Johann Gotthelf Fischer von Waldheim (1771-1853) - Charles Roulier (1814-1858) and Grigory E. Shchurovsky (1803-1884), Vladimir O. Kovalevsky (1842-1883), Aleksei Petrovich (1854-1929) and Maria Vasilievna (1854-1938) Pavlovs, and Aleksei Alekseevich Borisyak (1872-1944). Brief biographical information of the scientists is provided. Their contribution to the development and organization of paleontological research at Moscow University is shown.
INITIAL PERIOD OF THE SCIENTIFIC ACTIVITY OF THE MICROBIOLOGIST AND EPIDEMIOLOGIST VLADIMIR A. BARYKIN: TO THE 150TH ANNIVERSARY OF HIS BIRTH
Authors: Gorshenin Alexander
Published: January 2025

In the year of the 150th anniversary of the famous Russian scientist Vladimir A. Barykin (1874-1939), an attempt is made to reconstruct the initial period of his scientific activity. Based on the documents from the State Archive of the Russian Federation and published sources, the pre-revolutionary stage in the life and work of V.A. Barykin is considered. The professional path of the scientist, his first scientific research, as well as participation in the Russian-Japanese and World War I are recreated. And although the flourishing of his scientific and organizational activities took place in the 1920s and 1930s, the pre-revolutionary period of his life was extremely busy with expeditions and research, becoming significant for the formation of a professional scientist and the definition of those research areas that he would develop later. The fruitful scientific activity of the scientist was interrupted in 1938, when he was arrested, and in 1939 he was shot during the repressions. Despite the rehabilitation of V.A. Barykin in 1955, no detailed publications about his life and scientific activity have appeared. This article attempts to fill in this research gap and honor the memory of the prominent Russian scientist in his jubilee year.
SERGEI S. NEUSTRUEV. HIS LIFE, ACTIVITY AND CONTRIBUTION TO THE DEVELOPMENT OF GENETIC SOIL SCIENCE: TO THE 150TH ANNIVERSARY FROM HIS BIRTHDAY
Authors: Pogozhev Evgeny
Published: January 2025

The article tells about the life and scientific achievements of this scientist. The major stages of S.S. Neustruev’s work are given: a theorist of soil science from Dokuchaev’s school, a famous geologist and one of the most talented physical geographers. His unique capacities for synthesis, a special ceaseless role of soil-geographical, cadastral and geological researches conducted by him are shown. S.S. Neustruev’s scientific views about the joint development of geomorphology and soil, their interconnections have developed approaches to develop regional Russian and global soil classifications and to study ecological and biosphere soil functions. New facts of his life and scientific activity are presented. He was a Russian soil scientist, geographer, naturalist, graduate from Moscow University, researcher of Central Asia, the South- East of the Russian Plain, and the Volga region. Being professor of the Geographical Institute in Petrograd (1918), he headed the first department of soil geography in Russia. He was the first to introduce the term “serozem” and establish the serozem type of soil formation in deserts and semi-deserts, and developed a classification of soils for a number of regions of Central Asia. He was Head of the Commission on Soil Genesis of the First All-Union Congress of Soil Scientists; Participant of the 1st International Congress of Soil Scientists in the USA (1927); Corresponding member of the Agricultural Academy (Czech Republic).
ГЛОБАЛІЗАЦІЙНІ ІМПЕРАТИВИ РОЗВИТКУ МІЖНАРОДНОГО РИНКУ
Authors: Бояр Андрій , Клець Віталій
Published: January 2025

The study examines the prerequisites for the company’s entry into the international market, describes the positive impact of advertising and mo- dern technologies on the level of product sales. It is noted that the digi- tal space enables the process of communication with consumers around the world in order to maintain the relevance of the product or its modi- fication. The meaning of the term «globalization» was characterized, the characteristics and prerequisites of globalization processes, their develop- ment (in historical terms) and consequences: positive and contradictory influence on the formation of the international market were determined. It was found that the technological and technical reality promotes the de- velopment of global markets of standardized goods at a low price due to the scale of production and the placement of production capacities in a favorable environment, due to which local companies become uncompeti- tive. It is noted that international trade is facilitated by globally educated workers who offer their services regardless of national borders. Global- ization has been proven to encourage each country to specialize in what it produces best, using the fewest resources. The phenomenon of a global corporation focused on the production of one product at an aggressively low price is considered. Cross-border political influence is described as a factor driving globalization. It was found that China’s influence on the international arena is growing, particularly in Africa. Countries by eco- nomic influence are divided according to the principle of supporters of China-Russia and the USA-Israel and Great Britain. Some results of the globalization of goods are described, both in highly developed countries and in those that are just developing. The state of globalization processes is analyzed. In particular, it is found that international trade liberalization soared in the nineteenth century due to the development of technology and the construction of transport routes, but global marketing has now slowed due to financial instability and increased political control.
 
The article prepared within the «Jean Monnet Centre of Excellence “Vo- lyn Centre for European Studies: Green and Secure Neighbourhood”» of the Erasmus+ Programme of the European Union (№ 101085647 – VCES – ERASMUS-JMO-2022-HEI-TCH-RSCH).
НАУКОВІ ПІДХОДИ ДО ТРАКТУВАННЯ ПОНЯТТЯ «МІЖНАРОДНА БЕЗПЕКА»
Authors: Присташ Анастасія
Published: January 2025

Due to the growing number of regional confrontations and the dynamic growth of global problems, the international security system is undergoing significant changes as part of world policy. The globalization of the world space has influenced the transformation of the security environment, created new actors in international relations, and led to new threats.
The rise of an aggressor in Eastern Europe was one of these challenges. This, in turn, triggered a split between supporters of democracy and autoc- racy. Outright violation of the current principles and norms of international law, development, and use of new types of weapons and military equip- ment, involvement of mercenaries, terrorist sponsors, and deepening coop- eration with North Korea – are all threats that have prompted an immediate search for new ways to respond to it in the system of international relations by developing practical strategic guidelines for stabilizing and balancing relations between the actors of world politics.
Therefore, the question of examining not only the existing approaches to interpreting the essence of the concept of “international security” but also the formation of new ones by auditing problematic issues in the system of international relations and analyzing methods and ways to overcome them has become relevant.
The article summarizes the approaches to defining the concepts of secu- rity, ‘national security,’ and ‘international security.’ It considers the leading and most common models of international security and spatial categories of geopolitical theory.
The article analyzes the scientific literature on international relations in the study context. The author provides an up-to-date list of challenges and threats that will affect significant changes in the formation of a new world order and measures to stabilize the international security system in the cur- rent situation
МЕДІАГРАМОТНІСТЬ ЯК ІНСТРУМЕНТ ПРОТИДІЇ ЗОВНІШНЬОПОЛІТИЧНІЙ ДЕЗІНФОРМАЦІЇ У ФІНЛЯНДІЇ
Authors: Юрій Аліна
Published: January 2025

The purpose of this article is to examine Finland's system of countering foreign political information interference, with a particular focus on the critical role of media literacy in ensuring national information security. The research explores key disinformation campaigns targeted at Finland, carried out by the Russian Federation and China. Historical, classification, comparative analysis, and con- tent analysis methods were employed. The article assesses the effectiveness of government support for media literacy strategies, institutional efforts, and in- ternational cooperation in countering disinformation. Special attention is given to the correlation between high levels of media literacy in Finnish society and the country's ability to effectively counter external information threats. The legal and documentary framework regulating disinformation countermeasures in Finland is also analyzed. The conclusion drawn is that successful resistance to foreign political disinformation in Finland is based on a comprehensive ap- proach combining high media literacy, legal regulation, and international col- laboration.
VISUALIZING MATH THROUGH WARLI ART: A CREATIVE APPROACH TO EFFECTIVE LEARNING
Authors: Rukari Seema , Kamble Namrata
Published: January 2025

Children always find mathematics a challenging subject, Sundaram an ex principal and Math educator in his book stated that “No other subject possibly evokes such strong and opposite emotional reactions as Mathematics does. This is the reason why in mathematics it is usually either “I understand it completely and love it” or “I cannot comprehend it at all and hate it.” There is rarely a middle ground. In many cases this “hate” develops into “math avoidance”, “math anxiety” or even “math phobia”.” Integration of Warli painting with Mathematics is used as one of the strategy for teaching learning. This research focuses on using Warli painting for mathematics teaching of class I students of English medium school of Pune city. The program was designed using warli painting to teach the concept of Addition and subtraction. The students were taught addition and subtraction using this strategy and few students were taught using the traditional teaching methods. A program was developed by the researcher and the effectiveness of the program was seen through implementation of the program followed by statistical analysis i.e. ‘t’ test was conducted to find out which was the more effective way for teaching mathematics to the students. The research was a mixed method research where both quantitative and qualitative techniques was applied. The feedback was taken from the students to know how useful they found this strategy in learning mathematic. The data was collected on a group of 30 control and 30 experimental students and true experimental design was selected. The results showed that the students in the experimental group enjoyed learning through warli painting and they understood the concept easily, they did not feel that they were studying.
Pengembangan model kolaborasi antara sekolah dan puskesmas dalam Implementasi trias uks berdasarkan pedoman nasional
Authors: Rohani Tuti , Darmawansyah  , Nurjanah Nimas Ayu Lestari , Wulandari
Published: January 2025

Trias UKS, mencakup Pendidikan Kesehatan, Pelayanan Kesehatan, dan Pembinaan Lingkungan Sehat, merupakan strategi penting untuk mempromosikan perilaku hidup bersih dan sehat di sekolah. Namun, implementasinya sering menghadapi kendala seperti keterbatasan fasilitas dan rendahnya koordinasi antara sekolah dan puskesmas. Penelitian ini bertujuan mengembangkan model kolaborasi antara sekolah dan puskesmas untuk meningkatkan implementasi Trias UKS sesuai pedoman nasional. Penelitian menggunakan pendekatan mixed-method dengan desain studi kasus multipel di lima sekolah (3 SD, 2 SMP) dan tiga puskesmas di Kabupaten Seluma. Data dikumpulkan melalui survei kuesioner, wawancara mendalam, FGD, dan observasi fasilitas sekolah. Analisis dilakukan secara deskriptif dan kualitatif untuk mengidentifikasi hambatan, peluang, dan strategi implementasi Trias UKS. Hasil penelitian menunjukkan bahwa hambatan utama mencakup keterbatasan fasilitas UKS, kurangnya integrasi pendidikan kesehatan, dan koordinasi yang belum optimal. Faktor keberhasilan meliputi koordinasi yang lebih baik, pembagian peran yang jelas, dan dukungan sumber daya. Model kolaborasi yang dikembangkan menawarkan pendekatan praktis untuk meningkatkan efektivitas implementasi Trias UKS. Kesimpulannya, model ini mampu menjawab berbagai kendala implementasi Trias UKS dengan pendekatan terstruktur dan berkelanjutan. Peneliti selanjutnya disarankan untuk menguji model ini melalui pendekatan longitudinal dan pengukuran dampak jangka panjang terhadap kesehatan siswa.
Administrasi pendidikan berbasis kecerdasan buatan: tinjauan sistematis, dan model implementasi berkelanjutan
Authors: Hutami Sari , Danim Sudarwan , Hamzah Syukri , Kristiawan Muhammad
Published: January 2025

Penelitian ini bertujuan mengeksplorasi pengembangan model implementasi kecerdasan buatan (AI) yang berkelanjutan dan adaptif dalam administrasi pendidikan, serta potensi penggunaannya di masa depan. Dengan menggunakan tinjauan sistematis terhadap 40 artikel dari database Scopus (2014–2024), penelitian ini menganalisis tren, tantangan, dan peluang penerapan AI. AI telah terbukti meningkatkan efisiensi administrasi melalui manajemen data, prediksi kinerja, dan alokasi sumber daya. Namun, keberhasilannya memerlukan sistem adaptif yang dapat beradaptasi dengan perubahan kebijakan, teknologi, dan kebutuhan pendidikan. Temuan utama dalam penelitian ini mencakup pentingnya integrasi aspek sosial, budaya, dan kebijakan untuk memastikan implementasi AI yang efektif dan etis. Tantangan signifikan meliputi perlindungan privasi data, etika algoritma, serta resistensi terhadap perubahan. Solusi yang disarankan mencakup pengembangan regulasi perlindungan data, pelatihan literasi digital bagi tenaga kependidikan, dan model implementasi berbasis umpan balik. Hasil penelitian ini juga menekankan pentingnya pengembangan model implementasi kecerdasan buatan (AI) yang berkelanjutan dan adaptif dalam administrasi pendidikan. AI memiliki potensi besar untuk mendukung tugas-tugas administratif seperti manajemen data, prediksi kinerja, dan alokasi sumber daya. Namun, keberhasilan jangka panjang penerapannya tergantung pada kemampuan sistem AI untuk beradaptasi dengan perubahan lingkungan dan kebutuhan pendidikan. Penelitian ini juga menyoroti perlunya integrasi aspek sosial, budaya, dan kebijakan untuk memastikan implementasi AI yang efektif dan etis, serta pentingnya regulasi yang melindungi privasi dan keamanan data. Model AI yang diterapkan harus fleksibel, berorientasi pada umpan balik, dan mampu meningkatkan efisiensi serta transparansi dalam manajemen pendidikan, sehingga dapat mendukung pelaksanaan administrasi Pendidikan secara lebih optimal dan mendukung tercapainya tujuan pendidikan nasional yang berkualitas, adaptif, inovatif dan inklusif.
Monetary and fiscal policy: drivers of stability in developing economies
Authors: Hakimah Yusro
Published: January 2025

This paper investigates the role of monetary and fiscal policy in ensuring macroeconomic stability, specifically in the context of economic growth and inflation within developing countries. Using a qualitative approach, the study extensively reviews existing literature and employs library research to explore how these policies impact the economic dynamics of developing nations. The research identifies key theoretical frameworks and empirical evidence that explain the interactions between monetary and fiscal policy and their collective influence on inflation rates and economic growth. It highlights that while monetary policy, primarily through interest rates and money supply management, can influence inflation, fiscal policy via government spending and taxation—plays a crucial role in sustaining long-term economic growth. The study further explores the challenges faced by developing countries in balancing these policies, particularly in the face of external shocks and structural vulnerabilities. Through the synthesis of various studies, the paper concludes that a well-coordinated monetary and fiscal policy framework is essential for achieving macroeconomic stability. Effective coordination between these policies can mitigate inflationary pressures, promote sustainable economic growth, and enhance resilience against global economic uncertainties. The paper provides recommendations for policymakers in developing countries on optimizing these policy tools to foster economic stability and growth.
Molecular Dynamics Study of Carbon Dioxide Gas Within Ice XVII Structure
Authors: Arman Yudha , Artedi  , Hasanuddin
Published: January 2025

We conducted a molecular dynamics study on CO2 hydrate within the ice XVII structure to examine the molecular diffusion of CO2 molecules, as it is essential to the hydrate potential as a carbon capture. The simulated CO2 hydrate system used 324 water molecules and 90 CO2 molecules. We used the TIP4P/Ice model for water molecules, and the CO2 molecules were treated as united atom. The simulations were carried out at 273,15 K under various pressures of 200 MPa, 500 MPa, and 1000 MPa for 1,50 ns, with a step size of 1 fs. The results showed that the CO2 molecules were confined and freely moved inside the cage-like chiral tube along the c-axis of the ice XVII structure. No significant inter-cage hopping was observed during the evolution of all simulated systems. The diffusion coefficient values for CO2 molecules within the ice XVII structure were 5.03 × 10-8 cm2s-1, 2.45 × 10-8 cm2s-1, and 8.86 × 10-8 cm2s-1  for the respective pressure variations of 200 MPa, 500 MPa, and 1000 MPa, resulting in an inverse proportional with the system's pressure. A higher diffusion coefficient facilitates a faster the mass transfer and adsorption rate of CO2 in formation build up of the CO2 hydrate system.
Development of Thematic Learning Using the Field-Trip Method Assisted by the Surrounding Environment to Improve Students' Scientific Literacy Abilities
Authors: Luah Sri , Parmin Parmin , Widiasih Widiasih
Published: January 2025

The purpose of this study is to produce learning tools with a field-trip learning method assisted by the surrounding environment to improve students' scientific literacy skills. The learning tool developed in this class VI material has the theme of saving living things with the subtheme of plants, friends. Development device learning refers to the Borg & Gall model which consists of 7 steps. Thematic learning tools with the field-trip method assisted by the surrounding environment were validated by 3 expert validators in the fields of science, language and instructional design learning so that results that met the following valid success criteria were obtained: Syllabus 4.48 (very good category), RPP 3.95 (good category), student teaching materials 3.81 (good category), and LKS 4.35 (very good category). The results of the effectiveness test of the learning tool were carried out on grade VI students of SDN Dampyak 02, resulting in an increase in scientific literacy skills of 4.14 (good category). Effectiveness was also obtained when teachers managed learning by 4.56 (very good category). The level of practicality of the field trip method during learning was 4.14 (good category), 4.30 (very good category). Thus, the overall learning tools of the field trip method developed are valid, effective, and practical.
REFLEXÕES SOBRE A PROFUNDIDADE DA COR DOS CABELOS DENTRO DA ESCALA DE REAÇÃO DO FUNDO DE CLAREAMENTO PARA AS ESTAÇÕES SAZONAIS
Authors: Pinheiro Alexandre
Published: January 2025

Este artigo esclarece o conceito de fundo de clareamento no processo de descoloração e oxidação dos pigmentos naturais dos cabelos, destacando sua importância na coloração pessoal e consultoria de imagem que é a cor visível que surge após o alvejamento dos fios, resultante da oxidação dos melanócitos e é essencial para a determinação da cor de reação final dos cabelos. O estudo analisa como a profundidade e a temperatura do fundo de clareamento afetam a cor final, permitindo aos profissionais fazerem recomendações mais precisas. A compreensão da profundidade e temperatura para alinhar as cores aos padrões das cartelas de cores sazonais e características individuais dos clientes. Além disso, o artigo detalha a escala de cores das reações reveladas durante a descoloração e coloração oxidativa, associando essas cores às características dos cabelos e às cartelas de coloração pessoal. Orienta profissionais da área de beleza sobre como utilizar esse conhecimento para diagnósticos e recomendações de cores adequadas, minimizando danos e aprimorando a qualidade dos serviços prestados. A abordagem expositiva e descritiva é fundamentada em conhecimentos teóricos sobre a estrutura capilar e os efeitos da oxidação.
O USO DAS CORES NOS TEMPOS BÍBLICOS
Authors: Vieira Cristiane Azevedo Lourenço
Published: January 2025

A Bíblia é o livro mais lido e vendido no mundo. O livro de Apocalipse descreve as visões detalhadas de João durante seu exílio na ilha de Patmos, incluindo a descrição das cores nos contextos sagrados. O objetivo da pesquisa é identificar as cores utilizadas nos tempos bíblicos, especificamente no livro Apocalipse, e promover uma análise sobre o significado de cada uma delas, relacionando com outras áreas do saber, como a psicologia das cores e a história da moda. Após revisão narrativa, foram identificadas as cores: branco, vermelho, preto, verde, púrpura e ouro. Cada uma delas apresenta uma simbologia específica. Conclui-se que desde o início dos tempos as cores já transmitiam uma mensagem específica. Com o passar dos anos, as cores mantiveram os seus significados e efeitos psicológicos muito similares, perdurando até os dias atuais. Novas pesquisas são sugeridas.
Pensadores negros transnacionais e circulação de ideias de escola e raça no Brasil e EUA
Authors: Ribeiro Jonatas Roque
Published: January 2025

O objetivo da comunicação é estudar a constituição de ideias pedagógicas antirracistas e projetos políticos de igualdade racial no âmbito da escola primária pública no início do século XX. Para isso,
La educación informal y la narrativa violenta contra las mujeres en los videos musicales
Authors: Gaytán Villalpando Beatriz Adriana
Published: January 2025

El presente artículo tiene como objetivo dar un acercamiento al por qué el incremento de la violencia de género hacia la mujer se ha agudizado de manera alarmante en México. A la luz de la transdisciplinariedad, la pedagogía, la perspectiva de género y masculinidades, se analiza el género de música regional mexicana más escuchado en México. Se sitúa el análisis en un contexto patriarcal feminicida donde las cifras oficiales no se acercan a las que informan los medios de comunicación o las organizaciones civiles. Se debe mencionar que es importante analizar de qué manera son interiorizados los videos musicales y su gran alcance en la población; gracias a las plataformas digitales y su influencia en algunas personas que los consumen en su vida diaria, se puede afirmar que el video musical, desde una mirada pedagógica, es una herramienta didáctica por excelencia en la educación informal y con ella “aprenden” muchos mexicanos a conducirse.
Admitir y aceptar: la instrucción pública de Campeche durante las administraciones científicas, 1902-1907
Authors: Dimas Mijangos Jorge
Published: January 2025

Este estudio analiza los discursos sobre instrucción pública presentes en los informes de gobierno de Campeche durante el periodo denominado “científico” (1902-1907). Se observa una marcada contradicción: mientras administraciones anteriores habían omitido casi cualquier mención a una crisis educativa, los gobiernos “científicos” encabezados por José Castellot y sus sucesores reconocieron públicamente la existencia de una grave problemática en el sector educativo. Esta repentina atención a la instrucción se explica por varios factores. Por un lado, implementar reformas educativas concretas, como la Ley de Instrucción Pública de 1902 y la mejora de las infraestructuras escolares. Por otro lado, esta estrategia tenía un objetivo político: desacreditar a las administraciones anteriores, vinculadas al grupo barandista, y legitimar el nuevo gobierno a través de la resolución de problemas sociales como el atraso educativo.
É POSSÍVEL PREVENIR A HIPERTENSÃO COM A ALIMENTAÇÃO? O QUE DIZEM AS EVIDÊNCIAS CIENTÍFICAS A ESTE RESPEITO?
Authors:   Universidade de São Paulo. Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Ribeirão Preto, SP, Brasil., Cesarino Evandro José ,   Associação Ribeirãopretana de Ensino, Pesquisa e Assistência ao Hipertenso – AREPAH. Ribeirão Preto, SP, Brasil, Castro Marildes Luiza ,   Hospital das Clínicas. Faculdade de Medicina da Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brasil., Garcia de Andrade Regina Célia ,   Universidade de São Paulo. Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Ribeirão Preto, SP, Brasil., de Godoy Costa Simone ,   Universidade de São Paulo. Escola de Enfermagem de Ribeirão Preto. Ribeirão Preto, SP, Brasil, Neto Espindola Larissa ,   Hospital Santa Izabel. Salvador, BA, Brasil, Baraldi A.Restini Carolina ,   Associação Ribeirãopretana de Ensino, Pesquisa e Assistência ao Hipertenso – AREPAH. Ribeirão Preto, SP, Brasil,   Michigan State University. College of Osteopathic Medicine. Department of Pharmacology and Toxicology. East Lansing/Clinton Township, MI, United States
Published: January 2025

A hipertensão arterial sistêmica (HAS) é um dos principais fatores de risco para doenças cardiovasculares (DCV) e pode ser influenciada por fatores genéticos, ambientais e sociais. Evidências científicas indicam que a dieta desempenha um papel crucial na prevenção e no controle da HAS, mas poucos artigos reúnem e comparam estratégias aceitas em diretrizes com evidências de alternativas não farmacológicas. Esta revisão aborda aspectos científicos baseados em evidências sobre como a dieta pode prevenir e ser um fator aditivo no tratamento farmacológico da HAS. O consumo elevado de sal está associado ao aumento da pressão arterial (PA) e a complicações renais. O consumo excessivo de álcool conhecidamente eleva a PA. Suplementação com potássio, cálcio, magnésio e vitaminas D e C se mostra benéfica na redução da PA, embora a eficácia dessas intervenções possa variar de acordo com a população e hábitos alimentares. A dieta mediterrânea é fortemente associada à redução do risco de HAS e DCV, embora os efeitos sobre a PA ainda necessitem de mais estudos. A dieta DASH (Dietary Approaches to Stop Hypertension), que significa “Abordagens Dietéticas para Parar a Hipertensão”, é baixa em sal e rica em frutas, vegetais, grãos integrais, laticínios desnatados e proteína magra, e é uma das abordagens dietéticas mais eficazes para reduzir a PA. Alimentos e suplementos, como alho, chocolate amargo, ômega 3, suco de beterraba, linhaça e probióticos, também apresentam potencial na prevenção e controle da HAS. Contudo, mais pesquisas são necessárias para confirmar a eficácia e segurança de algumas dessas intervenções
Efficacy of laser nucleoplasty and radiofrequency neuromodulation in the treatment of discogenic lumbar radiculopathy
Authors: Larionov S. N. , Zhivotenko A. P. , Sorokovikov V. A. , Gorbunov A. V. , Potapov V. E.
Published: January 2025

Back and lower limb pain interferes with patients’ daily lives and ultimately reduces their quality of life. Many interventional treatments have been proposed to reduce and prevent the development of chronic pain syndrome.

The aim of the study. To evaluate the effectiveness of the simultaneous use of laser nucleoplasty and radiofrequency neuromodulation of radicular nerves and ganglia in the treatment of discogenic lumbar radiculopathy.

Materials and methods. The  study included 20  patients; the  mean age was 39 ± 9.1 years. All patients underwent laser nucleoplasty of the LIV/LV intervertebral disc and radiofrequency neuromodulation of the radicular nerve in the foraminal space of  the  level of  interest and  localization of  pain. An  assessment of  changes in pain intensity and quality of life was carried out according to scales in the preand postoperative period and a control magnetic resonance imaging (MRI) study at the time of discharge, 3 months of observation, with an assessment of the volumetric indicators of the intervertebral disc.

Results. Patients showed a decrease in pain intensity according to the Visual Analogue Scale and an improvement in quality of life assessed by the ODI (Oswestry Disability Index) and SF-36 (Short Form 36) questionnaires. According to MRI studies, volumetric indicators increased after surgery and subsequently decreased by the 3rd month of observation.

Conclusion. The study demonstrates the possibility of using several interventional treatment methods simultaneously with an impact on various morphological substrates that cause the  formation of  pain syndrome. It  is  shown that a  decrease in the intensity of pain syndrome correlates with an increase in the volumetric indicators of the intervertebral disc according to MRI data immediately after surgery, with a subsequent decrease by 3 months of observation. Simultaneous use of laser nucleoplasty and  radiofrequency neuromodulation is  justified in  the  treatment of radiculopathy, allowing reducing the intensity of pain syndrome and increasing the volumetric indicators of the intervertebral disc, which is a sign that increases the shock-absorbing properties of the intervertebral disc.
Testing of a promising gel for the prevention of epidural fibrosis in an experiment on a laminectomy model
Authors: Zhivotenko A. P. , Shurygina I. A. , Shurygin M. G. , Goldberg O. A. , Larionov S. N. , Sorokovikov V. A.
Published: January 2025

Surgical treatment of  spinal diseases is  often complicated by  epidural fibrosis, which is one of the main causes of failed back surgery syndrome.

The aim. To evaluate the laminectomy zone and transformation of epidural fibrosis using original gels in an experiment.

Materials and methods. Laminectomy was performed on  male Wistar rats. The animals were divided into four groups. The original gels were tested. The group of intact (unoperated) rats served as a comparison group for the control and groups with the tested gels, carrying and not carrying the p38 MAP kinase blocker. On day 28, the deformation of the dural sac was assessed by measuring the transverse and longitudinal sections of the spinal canal, also the adhesion of the spinal roots to the inner layer of the dura mater in epidural fibrosis and its coverage with connective tissue along the perimeter of the laminectomy window were determined.

Results. In the control group, the pronounced deformation ofthe dural sac was observed. The use of all the studied gels reduced the deformation, bringing the shape ofthe dural sac closer to the norm. However, the gel with the p38 MAP kinase blocker significantly reduced the adhesion of the spinal roots to the dura mater.

Conclusion. For the first time, a pharmaceutical composition containing a p38 MAP kinase blocker was used andstudied ona laminectomy model forthe prevention of epidural fibrosis, and the relationships between the transformation and change in the shape of the dural sac with an assessment of the involvement of the dura mater in the formation of epidural fibrosis were presented. The results obtained show that a gel with a p38 MAP kinase blocker is more effective for the prevention of epidural fibrosis than a gel without a blocker.
Pro-inflammatory and anti-inflammatory cytokines in neonates during the acute period of novel coronavirus infection
Authors: Moskaleva E. V. , Petrova A. G. , Rychkova L. V. , Sholokhov L. F. , Akhmedzyanova M. R. , Semenova N. V. , Novikova E. A. , Kharkhorina A. A. , Kolesnikova L. I.
Published: January 2025

Background. Research results on the immune response and cytokine profile in children with the new coronavirus infection SARS-CoV-2 are contradictory and insufficient, which necessitates the need to understand the nature of the course of the disease depending on age and severity of the infection. The importance of assessing risks and predicting the consequences of a new coronavirus infection in childhood makes the study of serum concentrations of pro-inflammatory and anti-inflammatory cytokines relevant.

The aim. To study the level of pro-inflammatory and anti-inflammatory cytokines in newborns during the acute period of a new coronavirus infection to determine the characteristics of the immune response and identify prognostic criteria for the course of the infectious process.

Materials and methods. The article presents the results of a study of the level of pro-inflammatory, anti-inflammatory cytokines and C-reactive protein (CRP) in newborns (n  =  44) hospitalized with a confirmed new coronavirus infection of varying severity. The study was conducted during the acute period of COVID-19.

Results. Cytokine concentrations in the blood serum of newborns were determined by enzyme immunoassay. In newborns in the acute period of a new coronavirus infection, regardless of the severity, there is a decrease in serum concentrations of interleukin-1β, interleukin-4, interleukin-6, interleukin-8, tumor necrosis factor α, interferon (INF)  γ and  CRP compared with the control group. The level of INF-α in the blood serum of newborns of both the main and control groups did not have significant differences.

Conclusions. The cytokine profile in newborns with the new coronavirus infection SARS-CoV-2 may be due to inhibition of the innate immune system, which requires further research in this direction and increased pediatric attention to this category of children.
New strategies for the treatment of infections caused by biofilm-producing Klebsiella pneumoniae
Authors: Fadeeva T. V. , Nevezhina A. V.
Published: January 2025

Treatment of Klebsiella pneumoniae infections is becoming increasingly challenging due to their multiple resistance to current antimicrobials. The ability to form biofilms is a critical virulence feature of K. pneumoniae. Biofilms are complex bacterial communities consisting of  one or  more species embedded in  an  extracellular matrix of  proteins, carbohydrates, and  DNA. Inhibition and  killing of  biofilm-producing strains with  antibiotics often requires higher concentrations than those required to suppress planktonic bacteria. Dosage increases can vary significantly depending on many of their virulence factors. Therefore, alternative treatments have been sought recently. In this review, the literature was analyzed to gain insight into the major virulence factors with an emphasis on the role of biofilms in enhancing antimicrobial resistance, highlighting the importance of this mechanism for bacterial adaptation. The literature search was conducted using the electronic information resources PubMed, Google Scholar and eLibrary. The search depth was limited from 2000 to the present, the  share of  literature for  the  last 5  years was  63  %. The  keywords used in the search were: Klebsiella pneumoniae, biofilm, virulence factors, infection treatment, combination therapy. The concepts of the difference between the pathotypes of K. pneumoniae, hypervirulent and classical, and their relationship with biofilm formation are revealed. The composition and regulation of biofilm are characterized, some factors influencing the  structure of  biofilm are  briefly described. Some new combination strategies for the treatment of infections caused by biofilm-forming K.  pneumoniae are also presented. Understanding the  effect of  antimicrobials on biofilms is of paramount importance for clinical practice due to the increased level of resistance and the spread of resistance among infectious agents.
Detection and molecular genetic characterization of segmented flavi-like Yanggou virus in Dermacentor nuttalli Ol. (1929) ticks in Buryatia
Authors: Kartashov M. Yu. , Khankhareev S. S. , Krivosheina E. I. , Svirin K. A. , Kurushina V. Yu. , Ternovoi V. A.
Published: January 2025

The unfavorable epidemiological situation with tick-borne vector-borne infections may be characterized not only by an increase in the occurrence of already known diseases, but also by the identification of new infections and pathogens, the role of which remains poorly understood. An example of such pathogens is Yanggou tick virus (YGTV), which belongs to the group of segmented flavi-like viruses.

The  aim. To  detect and  molecular genetic characterization of  YGTV found in Dermacentor nuttalli Ol. (1929) ticks on the territory of the Republic of Buryatia.

Materials and methods. The study analyzed 350 individual samples of adult ticks of D. nuttalli species collected in the spring-summer period of 2023 on the territory of five districts of the Republic of Buryatia. The detection of YGTV RNA was performed by PCR followed by nucleotide sequence determination and phylogenetic analysis for each of the 4 genome segments.

Results. In one sample of  the  tick D.  nuttalli, collected in  the  Ivolginsky district of the Republic of Buryatia, YGTV RNA was detected, which was further confirmed by sequencing of the obtained genome fragment. The incidence of YGTV RNA among the studied D. nuttalli ticks in Buryatia was 0.3 % (95 % CI: 0.1–1.6). Primers were designed to obtain fragments of all four segments of the YGTV genome. The identified genetic variant of YGTV, when analyzed phylogenetically across all four segments, clearly clusters with YGTV sequences found earlier in China and Russia (the Republic of  Altai and  Tyva). The  detected variant shows the  highest sequence identity with the prototype strain Erzin14-T20074.

Conclusion. The study shows for the first time the presence of YGTV in the territory of the Republic of Buryatia, which actualizes the need to monitor the circulation of this virus in natural foci of tick-borne infections in this territory, as well as to further clarify the boundaries of the spread of flavi-like viruses potentially dangerous for humans.
Automating financial compliance with AI: A New Era in regulatory technology (RegTech)
Authors: Hariharan Pappil Kothandapani
Published: January 2025

Integrating Artificial Intelligence (AI) into the financial sector has revolutionized regulatory compliance, enabling organizations to navigate complex regulatory landscapes with enhanced efficiency and accuracy. This paper explores the transformative role of AI in Regulatory Technology (RegTech), focusing on how machine learning, natural language processing, and predictive analytics are automating critical compliance functions.
These technologies empower financial institutions to detect fraudulent activities, monitor transactions, and identify non-compliance with unprecedented precision. By analyzing vast datasets, AI-driven tools can swiftly adapt to changing regulatory frameworks, mitigating risks and reducing operational costs. Through a comprehensive review of existing literature and case studies, this study highlights the practical applications of AI in areas such as Anti-Money Laundering (AML), sanctions compliance, and fraud detection. It further examines the challenges in deploying AI, including ethical considerations, data privacy concerns, and integrating AI systems into legacy infrastructures.
While AI offers significant advantages, its adoption introduces complexities, such as ensuring transparency, managing biases, and balancing automation and human oversight. The paper concludes by emphasizing the necessity of collaborative efforts among stakeholders to address these challenges and develop robust governance frameworks. Looking ahead, advancements in AI promise to further enhance compliance operations, but this requires a commitment to ethical practices and continuous innovation. By responsibly leveraging AI, the financial sector can achieve more effective, adaptive, and sustainable compliance strategies, ultimately fostering trust and resilience in an increasingly regulated global market.
Impact of health infrastructure facilities on health delivery in rural
Authors: JR Geetha  , Dr Nila Chotai
Published: January 2025

In India, the healthcare industry has grown to be one of the biggest in terms of employment and income. Healthcare includes clinical trials, hospitals, medical equipment, telemedicine, outsourcing, medical tourism, health insurance, and medical devices. The Indian healthcare industry is expanding quickly as a result of improved coverage, improved services, and rising public and private sector spending. In the paper titled "Impact of Health Infrastructure Facilities on Health Delivery in Rural," the function of health centers, their facilities, and their effects on the provision of health services are examined, along with the difficulties faced by the residents of Mandya district. The survey method was used by the researcher, and regression analysis was used to assess the impact of the data.
Anterior Staphyloma (Right eye) with Phthisis bulbi (Left eye): A case report
Authors: Nikita Nijhawan  , Jayashree S Shah  , Niveditha RK  , Lokesha HM
Published: January 2025

Background Staphyloma is a clinical condition characterized by an ectasia of the outer coats of the eye with an incarceration of the uveal tissue.[1] Phthisis bulbi is an end-stage clinical condition occurring due to severe eye injury or disease damage which leads to scarring, inflammation, atrophy and finally disorganization of globe and intraocular contents. [3,4]

Case presentation A 16 years old boy presented in the OPD with protusion of the eyeball (right eye) and shrunken left eye which is present since birth. He had history of trauma to right eye with stick 5 years back following which he complains of further increase in size of the eyeball to attain the present size. His chief complaint was pain in right eye. SLE showed anterior staphyloma (right eye) along with mild congestion, mild blepharitis and pannus. Perception of light was present in right eye. Left eye findings were suggestive of pthisis bulbi with calcification, narrowing of palpebral aperture. The left eye was sightless, sizeless, shapeless and perception of light is negative in left eye.

Conclusion Early identification of ophthalmological problems in infancy & prompt intervention is mandatory for anterior staphyloma. A comprehensive evaluation of the risk factors, control of ocular comorbid conditions, and an early and meticulous surgery can optimize results.
The revolutionary impact of ai in the automotive industry
Authors: Gaurav Gupta
Published: January 2025

The automotive industry is undergoing a revolutionary transformation through the integration of Artificial Intelligence (AI) technologies. This article examines the multifaceted impact of AI across manufacturing, autonomous vehicle development, smart factory solutions, and customer experience enhancement. The article highlights significant improvements in manufacturing efficiency, with AI-driven quality control systems achieving high accuracy in defect detection and reducing production costs substantially. In autonomous vehicle development, AI systems have demonstrated remarkable capabilities, with object detection accuracy reaching exceptional levels under optimal conditions and decision-making architectures processing multiple discrete decisions per second. The implementation of AI in smart factories has led to considerable improvement in overall equipment effectiveness, while customer experience enhancements have resulted in a significant increase in satisfaction scores. The integration of AI in supply chain management and market intelligence has yielded substantial operational improvements, with demand forecasting accuracy reaching impressive levels for short-term predictions and enabling meaningful reduction in inventory costs.
Case study of patient with diabetic nephropathy and emerging subacute cutaneous lupus erythematosus
Authors: Gurpreet Bawa Bansal  , Pragati Borge  , Vivekanand Chavan  , Ashish jain  , Prathmesh
Published: January 2025

Introduction: Diabetes is one of the chronic diseases spread worldwide. Diabetic kidney disease (DKD) also known as Diabetic Nephropathy, is a chronic, progressive disease that is the most common cause of end-stage renal failure. High BP with chronic blood glucose level damage tiny blood vessels in the kidney and their function. Cellular degradation in the nephron and podocytes of the renal glomeruli, contributes to the impairment of renal function. As diabetic nephropathy majorly seen in aged person precaution should be taken while selection of drug.

Case presentation: The patient, in this report, is a 60-year-old male who was working as driver. Patient having diabetic history in their family. His mother has diabetes mellitus. He is with 10 years history of both hypertension and diabetes mellitus. Then in 2021 he was also infected by COVID-19 during pandemic. After few weeks of recovery patient start experiencing swelling feet and lower legs during night time. Blood test reveals elevated creatinine level and patient suffered rapid progression of DKD. The condition known as diabetic nephropathy. Despite aggressive treatment, the patient finally became dialysis dependent. Now past few weeks the patient is also suffered from newly developing skin disease. His skin become getting darker. Histomorphological features suggestive of Subacute Lupus Erythematosus. Results and discussion: Now patient is following regular medication and diet. Patient taking doctor’s monthly appointment and following maintenance dialysis three times a week.