bluuebunny/crossref_metadata_2025 huggingface dataset:
Oregano essential oil and its main components Thymol and Carvacrol as alternatives to control citrus canker
Authors: Zamuner C. F. C. , Marin V. R. , Dilarri G. , Hypolito G. B. , Sass D. C. , Ferreira H.
Published: November 2022

Plant Essential Oils and their constituents are well-known for their properties as antimicrobial agents and are labeled as Generally Recognized as Safe (GRAS), prompting studies around their usage in the control of food-borne microorganisms and phytopathogens. In this study, we evaluated Oregano Essential Oil (OEO), Thymol (THY) and Carvacrol (CAR) for the control of Xanthomonas citri subsp. citri (X. citri). In vitro antibacterial assays revealed that CAR and THY inhibit X. citri growth at concentrations (100 ug.mL− 1 and 114 ug.mL− 1) lower than OEO (136 ug.mL− 1). Bactericidal effects were observed at 400 ug.mL− 1 for OEO and 200 ug.mL− 1 for CAR and THY. Investigating potential cellular targets for the compounds showed that after 30 minutes of exposure up to 84% of the cells had their membranes disrupted, prompting the membrane as the primary target. Phytotoxicicity evaluations using Lactuca sativa and Solanum lycopersicum seeds showed an acute toxic effect in all treatments above 200 µg.mL− 1, except for OEO and THY in S. lycopersicum at lower concentrations. Regarding their protective effect on citrus leaves, CAR showed no effect (0.39 lesions per cm2) when compared to the controls. OEO and THY were able to significantly reduce citrus canker symptoms (0.18 and 0.11 lesions per cm2, respectively). In addition, no toxic effects were observed on citrus leaves. THY inhibits X. citri growth and the development of citrus canker lesions. These results prompt THY as a viable alternative to be used in citrus canker management.
The mediating role of attitudes towards dementia on the relationship between dementia knowledge and behaviors towards persons with dementia: A cross-sectional study
Authors: Huang Hsiu-Li , Li Yang-Tzu , Bai Jing-Xuan , He Jia-Ming , Yang Shao-Wei
Published: November 2022

Background
The rising prevalence of dementia is a global health issue due to the worldwide increase in the number of adults over the age of 65 years. Persons living with dementia often experience discrimination in their life; thus, building a dementia-friendly community is important for reducing biases towards this population. The relationship between dementia knowledge, attitudes, and behaviors towards persons with dementia are significant factors in creating a dementia-friendly community. However, limited research has prevented a better understanding of the relationships among these variables. This study aimed to examine the mediating effect of attitudes towards dementia on the relationship between dementia knowledge and behaviors towards persons with dementia.
Methods
This was a cross-sectional survey with participants recruited from Wanhua District, Taipei City using a non-probability sampling method. Data were collected regarding dementia knowledge, attitudes, and behaviors using the Alzheimer’s Disease Knowledge Scale (ADKS), Approaches to Dementia Questionnaire (ADQ), and two researcher-developed self-administered survey questions on unfriendly behaviors towards persons with dementia, respectively. The correlation between dementia knowledge, attitudes, and unfriendly behaviors towards persons with dementia was determined with Pearson’s correlation coefficient. Multiple linear regressions investigated predictors of unfriendly behaviors towards persons with dementia. A simple mediation model was used to examine the mediation effect of attitudes on the relationship between dementia knowledge and unfriendly behaviors towards persons with dementia.
Results
A total of 313 participants were surveyed and the mean age of the respondents was 53.24 years (SD = 17.20; range = 20 to 90 years). Scores for dementia knowledge, attitudes and unfriendly behaviors towards persons with dementia were significantly correlated. Higher scores for knowledge (β=-0.16, p < 0.01) and attitudes towards dementia (β=-0.32, p < 0.001) were significantly associated with lower scores for unfriendly behaviors towards persons with dementia. A significant mediating effect of attitudes towards dementia was observed.
Conclusions
Attitudes towards dementia was a significant mediator in the relationship between dementia knowledge and unfriendly behaviors towards persons with dementia. Our findings suggest that increasing public awareness and knowledge about dementia could help the general population develop better attitudes towards dementia, which could subsequently help improve behaviors towards persons with dementia.
Antiplane fracture behavior of n nano-cracks emanating from a magnetoelectrically semi-permeable regular n-polygon nano-hole in magnetoelectroelastic materials
Authors: Wu Zhilin , Liu Guanting , Yang Dongsheng
Published: November 2022

Based on Gurtin Murdoch surface / interface model and complex potential theory, by constructing a new conformal mapping function, the fracture behavior on n nano-cracks emanating from a n-polygon nano-hole under far-field antiplane mechanical load, inplane electrical load and magnetic load is studied. The analytical solutions of stress intensity factor, electric displacement intensity factor and magnetic induction intensity factor at the crack tip are given under the boundary conditions of magnetoelectrically semi-permeable. In addition, numerical examples show that when considering the surface effect, the stress field intensity factor, electric displacement intensity factor and magnetic induction intensity factor have obvious size-dependence. The results of this paper show that when the defect size increases to a certain extent, the influence of the surface effect begins to decrease, and finally tends to the results of classical elastic theory.
Co-delivery of fucoxanthin and Twist siRNA using hydroxyethyl starch-cholesterol self-assembled polymer nanoparticles for triple-negative breast cancer synergistic therapy
Authors: Wu Zeliang , Tang Yuxiang , Chen Zhaozhao , Feng Yuao , Yu Dianwen , Hu Hang , Liu Hui , Chen Wei , Hu Yu , Xu Rong
Published: November 2022

Background: Triple-negative breast cancer (TNBC) represents the most aggressive subtype of breast cancer with an extremely dismal prognosis and few treatment options. As a desmoplastic tumor, tumor cells are girdled by stroma composed of tumor-associated fibroblasts (CAFs) and their secreted stromal components. The rapidly proliferating tumor cells, together with the tumor stroma, exert additional solid tissue pressure on tumor vasculature and surrounding tissues, severely obstructing therapeutic agent from deep intratumoral penetration, and resulting in tumor metastasis and treatment resistance. Fucoxanthin (FX), a xanthophyll carotenoid abundant in marine algae, has attracted widespread attention as a promising alternative candidate for tumor prevention and treatment. Twist is a pivotal regulator of epithelial to mesenchymal transition (EMT), and its depletion has proven to sensitize antitumor drugs, inhibit metastasis, reduce CAFs activation and the following interstitial deposition, increase tumor perfusion, and allow more drugs to be delivered across the tumor stroma.
Results: Herein, our studies proposed a novel self-assembled polymer nanoparticle (siTwist/FX@HES-CH NPs) based on the amino-modified hydroxyethyl starch (HES-NH2) grafted with hydrophobic segment cholesterol (CH). Systematic studies demonstrated that the co-delivery strategy of natural product FX and nucleic acid drug Twist siRNA (siTwist) could not only synergistically kill tumor cells, but also inhibit the CAFs activation and extracellular matrix synthesis. Loose tumor stroma further facilitated transvascular transport and deep penetration of nanoparticles, obviously alleviating the primary tumor burden and inhibiting lung metastasis.
Conclusions: This dually functional nanomedicine that targets both tumor cells and tumor microenvironment (TME) could form a potent anti-TNBC therapeutic cyclical feedback loop, providing a new paradigm for TNBC treatment.
PCBP1 overexpression protects dopaminergic neurons in a model of Parkinson's disease
Authors: yang chen , li hongyan
Published: November 2022

PCBP1, known as poly(C)-binding protein, is a multifunctional protein produced by reverse transcription of the full-length mRNA of PCBP2. PCBP1 can regulate gene expression at the transcriptional level and can physically interact with other cellular proteins to alter their functional pathways. In our team's previous studies, overexpression of PCBP1 has been found to be closely related to oxidative stress, protein ubiquitination pathway, and iron death. In the present study, we provide evidence for a neuroprotective role of PCBP1 in dopaminergic neurons. Our data suggest that increased expression of PCBP1 in PC12 cells attenuates cellular damage caused by MPTP, including attenuated apoptosis and improved mitochondrial membrane potential. Overall, our data suggest a neuroprotective role for PCBP1 overexpression in dopaminergic neurons. These findings suggest that PCBP1 may have great therapeutic potential for the treatment of diseases associated with dopaminergic neuron loss, such as PD.
Toxic epidermal necrolysis (TEN) after sclerosing tissue glue injection in oesophageal variceal ligation in patients with liver malignant tumors: A case report
Authors: Hao Liangchao , Cai Wei , Geng Xiuchao , Li Qiang , Zeng Zhaomu , Chen Hong , Zhang Yuhao , Ding Juan
Published: November 2022

Background
Toxic epidermal necrolysis (TEN) is one of the few allergic diseases with an acute onset and severe symptoms in dermatology. Drugs are the most important pathogenic factors for this condition. Referring to the relevant literature, TEN after endoscopic surgery has been rarely reported.
Case presentation:
A 58-year-old male patient with chronic liver disease was treated with oesophageal variceal ligation, sclerosing agent and tissue glue injection due to oesophageal and gastric variceal bleeding. After 2 days, the patient’s skin exhibited erythema to different degrees. After 10 days of dexamethasone treatment, the whole-body rash worsened, and a severe skin reaction appeared, which was suggestive of toxic epidermal necrolysis (TEN). Strict mucosal care was provided, and corticosteroids, gamma globulin and adalimumab were concurrently used for treatment. After 20 days, the patient recovered from the skin problems.
Conclusion
Combined with domestic and international case reports, this may be the first case report of toxic epidermal necrolysis after sclerosing tissue glue injection in oesophageal variceal ligation. When patients with multiple drugs have multiline erythema, physicians should be alert to the possibility of its development into TEN. This article summarizes the experiences of this patient and related diagnoses and treatments at home and abroad, which provides a practical clinical basis and experience for the diagnosis and treatment of TEN in the future.
Portrayals of Electronic Cigarette Use; A Content Analysis of News Coverage by Online News Sites in Africa
Authors: Ngoma Chimwemwe
Published: November 2022

Background
Electronic cigarette use has become an international phenomenon in recent years, with many countries reporting an increase in the number of electronic cigarette users. Despite this, it remains largely unclear how news about the use of electronic cigarettes is portrayed in Africa. This study examined how news on electronic cigarette use is portrayed in Africa.
Methods
Content analysis was conducted to reveal the prevalence of codes and themes. A thematic analysis was also undertaken to explore how the choice of news sources influences news framing.
Results
The study found that positively framed articles and arguments about e-cigarettes in Africa outnumbered negatively framed articles and arguments. The study also found that the health impacts of electronic cigarettes were the most discussed topic and health authorities were the commonly used news sources.
Conclusion
Despite public health authorities being the main news source, the study found that there was a lack of unison in the argument on the safety of electronic cigarette use which could result in public health consequences, such as the formation of uninformed policies.
Persistent Myocardial Dysfunction Assessed by Global Myocardial Strain in Covid-19 Recovered Patients with Cardiovascular Comorbidities at 3 Months after Acute Infection
Authors: Tanto Ines Vidal , Sukmawan Renan , Liastuti Lies Dina , Mulya Erwin , Danny Siska Suridanda , Ariani Rina , Dwiputra Bambang , Hazami Zakky , Kusuma Nabilla Merdika , Kuncoro BRM Ario Soeryo
Published: November 2022

Background
Previous studies reported the Coronavirus disease (COVID-19) has long implications, which involve multiple organs, including the cardiovascular system. This study aims to assess myocardial dysfunction by echocardiograph myocardial longitudinal strain Left ventricular-Global Longitudinal Strain (LV-GLS) and Right Ventricular-Free Wall Strain (RV-FWS) measurements as a marker for myocardial dysfunction and heart fibrosis. Additionally, we aim to identify admission factors that may serve as a predictor of long COVID syndrome.
Methods
This cross-sectional study assessed echocardiograph global longitudinal strain (GLS) values measurement done three months after initial hospitalization. Multivariate analysis was done to investigate admission factors associated with differences in GLS values.
Results
100 subjects with cardiovascular comorbidities and prior COVID-19 infection were enrolled. Echocardiography examination showed lower GLS values in this group compared to the normal population. Demographic and risk factors-matched subjects without a history of COVID-19 (n = 31, Control 1) and healthy subjects (n-31, Control 2) were included as comparisons to validate GLS results. The case group had significantly lower LV-GLS values compared to other groups (p < 0.05, mean ± SD -16.17 ± 3.379, -19.48 ± 1.141, -21.48 ± 1.777 respectively for case, control one, and control two groups). Upon admission, a history of coronary artery disease was found to be associated with decreased LV GLS values in recovered COVID-19 patients with cardiovascular comorbidity.
Conclusion
LV GLS values significantly decreased in recovered COVID-19 patients with cardiovascular comorbidities. Upon admission, a history of CAD may predict cardiac long COVID-19 syndrome.
Apple-shaped obesity; a risky soil for cytokine-accelerated severity in COVID-19
Authors: Hosoya Tadashi , Oba Seiya , Komiya Yoji , Kawata Daisuke , Kamiya Mari , Iwai Hideyuki , Miyamoto Sho , Kataoka Michiyo , Tobiume Minoru , Kanno Takayuki , Ainai Akira , Sato Hiroyuki , Hirakawa Akihiro , Satoh Takashi , Wakabayashi Kenji , Yamada Tetsuya , Otomo Yasuhiro , Miyazaki Yasunari , Hasegawa Hideki , Suzuki Tadaki , Yasuda Shinsuke
Published: November 2022

Obesity is one of the most significant risk factors for the deterioration and mortality associated with COVID-19 [1]. A certain proportion of COVID-19 patients experience marked elevations of inflammatory mediators, termed “cytokine storm”, resulting in the deterioration of the respiratory condition [2,3]. In the present study, we elucidate that the high visceral adipose tissue (VAT) burden was more closely related to accelerated inflammatory responses and the mortality of Japanese COVID-19 patients than other obesity-associated markers, including body mass index (BMI). To explore a novel stratification of COVID-19 patients, we infected mouse-adapted SARS-CoV-2 in several obese mice, revealing that VAT-dominant ob/ob mice and diet-induced obesity obese mice died after infection with low-titer mouse-adapted SARS-CoV-2 virus due to the subsequent cytokine storm, whereas none of the subcutaneous adipose tissue (SAT) dominant db/db mice or control lean wild-type mice died. SARS-CoV-2 genome and proteins were more abundant in the lungs of ob/ob mice, engulfed in macrophages, resulting in increased production of inflammatory cytokine represented by IL-6. As well as the anti-IL-6 treatment, the prevention of obesity by leptin administration improved the survival of SARS-CoV-2 infected ob/ob mice by reducing the viral protein burden and excessive immune responses.
In silico Characterization and Epitope Profiling of Differentially Expressed Plasma Membrane Proteins of ‘X’ and ‘Y’ Chromosome Bearing Bovine Sperm
Authors: Sharma Mridula
Published: November 2022

The specific and differentially expressed plasma membrane proteins of bovine sex sorted semen were selected after reviewing previous research publications related to proteomic profile of bovine sexed semen. The in-silico characters such as physicochemical properties, primary, secondary, tertiary structures, membrane topology, sub-cellular localisation, domain analysis, protein interactions and epitope profiling, both linear and discontinuous peptides was done for selected plasma membrane proteins by using various bioinformatics tools and software. The results showed localisation of protein along with their structure, polarity, stability, domains, their function and probable epitopes of various selected X and Y bovine sperm plasma membrane specific and differentially expressed proteins. For X specific protein CLRN3, 6 and 4 linear and discontinuous epitopes, and for Y chromosome specific protein, SCAMP1, 6 and 8 linear and discontinuous epitopes were predicted, respectively. The results of in silico characterization and epitope prediction of various selected X and Y bovine sperm plasma membrane specific and differentially expressed proteins would be helpful in selection of some efficient antigenic proteins to be used for further X and Y sperm specific antibody production or synthesis of antibodies artificially.
A two-stage new mode of satellite on-orbit mission planning
Authors: Wu Qianyu , Wang Mi
Published: November 2022

In order to improve the observation efficiency of intelligent remote sensing satellites and give full play to the application value of satellites, this paper proposed a new two-stage on-orbit mission planning model. The earth observation targets are divided into two types: fixed targets and user targets. This ensures that whereas dynamically and timely responding to the user targets, the utilization efficiency of satellite resources can be improved as much as possible, and provides a reference for judging whether the satellites are operating well. On this basis, this paper designs a two-stage on-orbit dynamic task planning scheme, which uses a greedy algorithm and a greedy algorithm based on heuristic rule to solve the fixed target stage and the user target stage. At the end of the article, a simulation test is carried out on the method of this paper, and the two-stage planning scheme is compared with the method of individual user target planning. The results proves that the method in this paper can achieve the priority planning of user goals, and verify the feasibility of the method in this paper.
RESTAURANT BUSINESS MANAGEMENT: INTERNATIONAL TRENDS
Authors: Shymoshenko A.
Published: November 2022

The article examines the current state of the restaurant business and trends in market development. The restaurant business and the hospitality industry are highly vulnerable to global shocks. The coronavirus epidemic events significantly impacted the industry and became a real shock for the owners of restaurants, cafes, and other public catering establishments. According to statistical data, the industry has become one of the sectors most affected by the restrictions that the governments of many countries have introduced to fight the spread of the coronavirus. Many institutions experienced a reduced business activity, and many other institutions were out of business. In particular, in the first year of the spread of the coronavirus, public catering establishments failed to receive about 27% of the projected income, which affected the financial stability of some establishments. In general, the indebtedness of business entities in this industry increased by 8.1% during the pandemic years. To minimize losses, companies resorted to reducing staff, switching to remote service ("takeaway"), including with the active support of delivery services, which, unlike the restaurant business, received some profit from the situation related to the pandemic.
A critical problem for the restaurant business in recent years has been the reduced number of visitors due to the imposed restrictions. According to estimates, the number of customers has decreased by two-thirds. The transition to work "to take away" and the use of online tools did not allow to eliminate the losses. Still, they softened the impact of the crisis on restaurants, coffee shops, and other establishments in the field of public catering. However, the reduction in the number of visitors is not only due to bans on visiting institutions. One of the main reasons was the decrease in the incomes of the population and, accordingly, the reduction of expenses. Food costs in the restaurant business are not a primary need. Therefore, these costs were cut by the population in the first place.
However, the coronavirus restrictions affected trends in the restaurant business. Along with the steady trend to consume healthy food, including food grown by local producers, it is worth noting the growing attention of consumers to comply with safe conditions and frequency in catering establishments and the use of web tools for choosing an establishment.
SIBLING RIVALRIES
Authors: Qodir Zuly
Published: November 2022

The issues of religious proselytization as well as the construction of house of worship are of main contentious topics inciting tensions between religious adherents, particularly between the minority Christians and the majority Muslims in contemporary Indonesia. This article discusses these two inter-religious problems and poses a question to extent that the competition between Muslim and Christians, both in their missionary activities and the building of new house of worship, inflicting inter-religious relation in contemporary Indonesia. Taken some cases as points of discussion, this article further offers that inclusive dialogue and social justice are solutions to minimize—even to prevent—the worsening tension between Muslim and Christians.
ARTICULATING TAKFIR
Authors: Asrori Saifudin , Bakhtiar Amsal
Published: November 2022

Takfir is an ideology of excommunicating fellow Muslims because of having different beliefs or expressing a different point of view. This article deals with the development of the takfir doctrine which separates some groups not only based on theological aspects but also on socio-political aspects, such as justifying the democratic system or collaborating with enemies of Islam. It particularly addresses the question of how Ayman al-Zawahiri globalized the takfir doctrine as a campaign against secularism, capitalism, human rights, and environmental crisis, in order to invite local jihadist groups to fight together in a global sphere.
IN SEARCH OF THE MOON
Authors: Musonnif Ahmad
Published: November 2022

This article deals with varieties of epistemological methods in calculating days of lunar calendar (hijri), mainly on the beginning date of months. Examining different methods in Indonesian Islamic-scape, it argues that there are three epistemological models which are rooted at Islamic classical epistemologies; the ahl al-hadith (textualist), the ahl al-ra‎y (contextualist), and the intuitive sufi. The ahl al-hadith emphasizes on the empirical rukyatul-hilal (witnessing the moon), whereas the ahl al-ra’y strongly concerns on the mathematically rational method. The sufi, not so popular in Indonesia but influential in some sufi circles, deploys the intuitive kashf (uncovering) method. In some cases, these three are however intertwined and in contradiction one to another. The article futher argues that different method-in-use is strongly influenced the local spesificties of diverse Indonesian Muslim’s backgrounds, and groupings.
TRANSCUTANEOUS ELECTRIC NERVE STIMULATION THERAPY IN TEMPOROMANDIBULAR DISORDERS- A SYSTEMATIC REVIEW
Authors: S.M Nayana , R.K Roopashri , P. Bhandarkar Gowri , S. Shetty Ujwala , H.C Meghana , Kini Raghavendra
Published: November 2022

Temporomandibulardisordercharacterizes a varied group of pathologies affecting temporomandibularjoints, masticatory muscles, or both.The treatment of temporomandibular disorders is a major challenge because of its varied causes and structures involved and also because the functioning of one joint is always dependent on the other. Transcutaneous electric nerve stimulation is a non-pharmacological method of pain control and recently it is gaining importance in treatment of temporomandibulardisorders. Hence this study was undertaken to analyze the effect of transcutaneous electric nerve stimulation on pain due to temporomandibular disorders and to compare the efficacy of transcutaneous electric nerve stimulation treatment over other treatments available for the same.Electronic search for articles published in various journals were undertaken through various search engines from 2020-2022. 9 randomized control trials of transcutaneous electric nerve stimulation therapy performed on temporomandibular disorder patients were selected for analysis. The efficacy of transcutaneous electric nerve stimulation therapy was compared with conventional therapy [muscle relaxant+ analgesic], low level laser therapy,Microcurrent Nerve Stimulation therapy, Physiotherapy, and Placebo therapy.Results of selected study conclude that transcutaneous electric nerve stimulation therapy is superior to all other treatment modalities included in the study in the treatment of pain due to temporomandibular disorders. Maximum reduction in pain was obtained in combination therapy of transcutaneous electric nerve stimulation with muscle relaxant, hot fermentation, and soft diet.Transcutaneous electric nerve stimulation along with medication proved to be highly effective in treating pain due to temporomandibular disorders.
RELATIONSHIP BETWEEN HBA1C AND COMPLETE BLOOD COUNT PARAMETERS IN ADULT PATIENTS WITH TYPE 2 DIABETES IN SAUDI ARABIA
Authors: A. Alodhayani Abdulaziz , A. Almansour Raghad , J. Alotaibi Jawaher , G. Alghamdi Ebtehaj , S. Alageel Mai , S. Binabbad Rahaf , M. Almutairi Wejdan
Published: November 2022

Background: Hemoglobin A1c (HbA1c) measures blood glucose over a period of 2â€“3 months, and its level is closely related to the risk of complications. Several factors affecting HbA1c levels have not been studied. This study mainly focused on the relationship between HbA1c levels and complete blood count (CBC) parameters. Objectives: This study aimed to analyze the relationship between HbA1c levels and CBC parameters in patients with type 2 diabetes mellitus (T2DM) and to evaluate the association of CBC parameters with abnormal HbA1c levels and diabetic complications. Methods: This was a retrospective study of 385 Saudi patients with T2DM aged â‰¥18 years attending King Khalid University Hospital (KKUH) primary care clinics. Patients with type 1 diabetes mellitus, hematological diseases, infections, or allergies were excluded. AnElectronic System for Integrated Health Information (e-SiHi)was used to collect data, which were analyzed using SPSS 22 using t-test and analysis of variance, with P <0.05 considered significant. Results: This study showed that the mean patient age was 59Â±13 years, with no significant difference between the sexes. In addition, the mean duration of disease was 10 years, and the mean HbA1c level was 8.5Â±1.9 %. CBC values were averaged according to their mean values, except for the erythrocyte sedimentation rate (ESR) (36Â±27 mm/hr) which was higher than the normal value (1.0â€“25 mm/hr). Conclusion: This study showed an association between HbA1c levels and duration of T2DM and hemoglobin. The progression of diabetic complications was related to CBC changes a high ESR was associated with the incidence of diabetic nephropathy and increased white blood cell count with neuropathy, vasculopathy, and nephropathy. Among all complications, vasculopathy occurred more frequently with each increase in HbA1c values.
Hubungan Kinerja Keuangan Perusahaan dan Nilai Perusahaan
Authors:   Prodi D4 Akuntansi Sektor Publik, Politeknik Keuangan Negara STAN, Jl. Bintaro Utama Sektor V, Bintaro Jaya, Tangerang Selatan, Banten, Indonesia, Tarigan Rezky Yosepha , Firmansyah Amrie ,   Prodi D4 Akuntansi Sektor Publik, Politeknik Keuangan Negara STAN, Jl. Bintaro Utama Sektor V, Bintaro Jaya, Tangerang Selatan, Banten, Indonesia, Shinta Ramadhani Dinis Dwi ,   Prodi D4 Akuntansi Sektor Publik, Politeknik Keuangan Negara STAN, Jl. Bintaro Utama Sektor V, Bintaro Jaya, Tangerang Selatan, Banten, Indonesia, Ikhsan Wishmy Meinawa ,   Prodi D4 Akuntansi Sektor Publik, Politeknik Keuangan Negara STAN, Jl. Bintaro Utama Sektor V, Bintaro Jaya, Tangerang Selatan, Banten, Indonesia
Published: November 2022

This study aims to investigate financial performance against value. CEO share ownership is used as a moderating variable in the relationship between the two. The company's performance in this study uses economic value added (EVA). The data used in this study are sourced from the financial statements and stock prices of non-financial companies listed on the Indonesian stock exchange from 2018 to 2020. The data are sourced from www.idx.co.id, the company's official website, and www.finance.yahoo.com. Sampling was conducted by purposive sampling with a total sample that can be used amounted to 84 observations. Research data were tested using multiple linear regression analysis for panel data. This study concludes that the company's financial performance negatively relates to firm value. Meanwhile, the CEO's share ownership did not succeed in having a moderating role in the relationship between firm performance and firm value. Based on the results of this study, the Financial Services Authority needs to increase the role of monitoring the company's performance in aligning the interests of investors.
A visão do usuário sobre o serviço odontológico especializado no Sistema Único de Saúde
Authors: Mário Filipe Verçosa de Melo Silva  , Gabriela da Silveira Gaspar  , Edson Hilan Gomes de Lucena  , Paulo Sávio Angeiras de Goes  , Nilcema Figueiredo
Published: November 2022

A satisfação do usuário é um importante componente da avaliação da qualidade de sistemas e serviços de saúde. Objetivo: Propor um indicador e avaliar fatores associados à satisfação de usuários em serviços odontológicos especializados no Sistema Único de Saúde (SUS). Material e métodos: Foi realizado estudo quantitativo e transversal utilizando dados do 1.º ciclo de Avaliação Externa do Programa de Melhoria do Acesso e da Qualidade dos Centros de Especialidades Odontológicas (PMAQ/CEO). Fizeram-se elaboração e descrição de dados do Indicador de Satisfação dos Usuários do PMAQ/CEO e foram verificados os fatores associados à satisfação de usuários dos serviços por meio do teste qui-quadrado de Pearson e regressão logística binária simples (p<0,05). Resultados: A média dos escores de padrões de satisfação foi de 9,9 (±1,7). Encontrou-se maior nível de satisfação entre os participantes da região Sudeste (15,9%), de serviços CEO tipo II (14,4%), numa idade de 41 a 52 anos (14,5%), >< 0,05). Resultados: A média dos escores de padrões de satisfação foi de 9,9 (±1,7). Encontrou-se maior nível de satisfação entre os participantes da região Sudeste (15,9%), de serviços CEO tipo II (14,4%), numa idade de 41 a 52 anos (14,5%), cujas consultas foram agendadas por telefone (20,0%) com horário definido (17,9%) e para especialidade de ortodontia/ortopedia (20,7%). Conclusão: A satisfação esteve associada a usuários de serviços da região Sudeste do Brasil, para especialidade de ortodontia/ortopedia e para marcações de consultas por telefone com horário definido.
Arquivamento pelo paciente de dados médicos e odontológicos úteis para identificação humana
Authors: Caren Victória Benevente Candido Ferreira  , Maria Izabel Cardoso Bento  , Rachel Lima Ribeiro Tinoco
Published: November 2022

O prontuário odontológico, um dos documentos mais importantes e amplamente utilizados na identificação humana, oferece, por meio de seus registros e exames complementares, qualidade e quantidade de detalhes únicos. Assim, o cirurgião[1]dentista passa a ser uma figura importante no auxílio do processo de identificação. Por mais que a elaboração do prontuário seja um dever do profissional, ainda é um passo muitas vezes negligenciado. Nessas circunstâncias, o arquivamento de tais documentos, sejam eles médicos ou outros meios de individualização, pela família é o que permite a aplicação de um método identificatório. Objetivo: Conhecer quais tipos de documentos que podem ser úteis na identificação humana são geralmente arquivados. Material e métodos: Utilizou-se um questionário composto por dez perguntas sobre a condução dos participantes com o arquivamento ou não de registros que permitiam uma possível identificação humana. Resultados: Dentre os exames que poderiam colaborar para identificação humana, encontra-se a radiografia, especialmente a panorâmica. Entretanto, apesar de a maioria dos pacientes reconhecer a importância de guardar exames médicos e odontológicos, mais de 80% dos participantes não costumam solicitá-los de volta aos profissionais de saúde. Conclusão: A população leiga seria muito beneficiada com campanhas de conscientização para valorização desses exames, visando, a médio e longo prazo, facilitar o processo de identificação humana, com maior número potencial de dados ante mortem.
Índice de acerto da hipótese do diagnóstico clínico e diagnóstico anatomopatológico: experiência do serviço de cirurgia bucomaxilofacial de um hospital oncológico
Authors: Luis Gustavo Schlickmann de Souza  , Roberta Targa Stramandinoli-Zanicotti  , Juliana Lucena Schussel  , Laurindo Moacir Sassi
Published: November 2022

Nos primórdios da Odontologia a cavidade bucal era considerada apenas um local onde havia dentes, alterações periodontais e cáries. Com a evolução dos estudos na área, começou-se a dar mais importância à região, observando diversos processos patológicos. O diagnóstico correto das mais variadas lesões que acometem o sistema estomatognático é essencial, e o conhecimento da frequência relativa ou prevalência dessas lesões na população constitui uma ferramenta importante para o diagnóstico clínico. Material e métodos: Foi realizado um levantamento epidemiológico com abordagem qualitativa, retrospectiva, por meio da análise dos prontuários médico-hospitalares eletrônicos de todos os pacientes que realizaram biópsias no ambulatório do Serviço de Cirurgia Bucomaxilofacial de um hospital oncológico no período de dois anos, buscando o índice de acerto da hipótese clínica com o diagnóstico definitivo da análise anatomopatológica. Resultados: O índice de acerto da hipótese do diagnóstico clínico e diagnóstico anatomopatológico foi de 76,9%. Carcinoma espinocelular foi o diagnóstico anatomopatológico mais frequente, com 112 casos (12,9%). O grupo de lesões biopsiadas com menor porcentagem de erro foi o das lesões ósseas, com 5,37%, e o com maior porcentagem de erro foi o de outras lesões orais em tecido mole, com 49,01%. Conclusão: Conclui-se que uma correta formulação da hipótese diagnóstica, além de auxiliar o patologista no correto diagnóstico, é fundamental para que se tenha um melhor seguimento do caso e plano de tratamento, uma vez que uma lesão de aspecto maligno exige medidas mais urgentes que uma lesão de caráter benigno.
O metabolismo ósseo em lesões periapicais: revisão de literatura
Authors: Isadora Morais de Souza  , Liliane Roskamp  , Natanael Henrique Ribeiro Mattos  , Camila Paiva Perin  , Cintia Milani Mussi  , Julia César Durski  , Erika Calvano Küchler  , Isabela Ribeiro Madalena  , Flares Baratto-Filho  , Maria Carolina Botelho Pires de Campos
Published: November 2022

A lesão apical está relacionada a progressão de lesões de cárie ou traumatismos dentários, que levam a polpa à inflamação e necrose, resultando, em alguns casos, em perda dentária. Quando persistente, o processo patológico não se reverte sem tratamento adequado. Objetivo: O estudo discorre sobre como, após ocorrer os fenômenos de necrose pulpar, acontece o processo de reabsorção e reparo ósseo apical, com a finalidade de compreender como a instrumentação e a limpeza do sistema de canais radiculares podem contribuir para a neoformação óssea na lesão periapical. Material e métodos: Utilizou-se o método de revisão integrativa da literatura. O estudo descreve o processo de reabsorção óssea e os seus estágios, destacando a importância dos receptores RANK, RANKL e a OPG, os quais possuem significativa importância na regulação do metabolismo dos tecidos duros. Resultados: A limpeza do sistema de canais radiculares é relevante para a supressão de agentes estimuladores de reação imunoinflamatória, como microrganismos e citocinas pró-inflamatórias. Nesse processo, o hidróxido de cálcio possui alta eficiência para eliminação de bactérias, principalmente anaeróbicas. Conclusão: Para alcançar o reparo da lesão periapical, é necessário atuar modulando a reação imunoinflamatória no local, removendo os agentes patogênicos, mediante técnicas e produtos que estimulem a ligação de RANKL/OPG, de modo a favorecer a estimulação de células blásticas, que promoverão o reparo do tecido ósseo.
Flare-ups em Endodontia: uma revisão de literatura
Authors: Letícia Kimberle Furquim Silveira  , Aline Teixeira Mendes  , Carla Cioato Piardi
Published: November 2022

Flare-up é um termo utilizado em Endodontia representado por sintomatologia dolorosa ou edema, ocorrendo algumas horas ou dias após o processo endodôntico. Estudos apontam que sua etiologia é multifatorial, com origem em fatores mecânicos, microbianos e químicos. Objetivo: Revisar a literatura existente sobre os fatores associados a flare-ups em Endodontia. Material e métodos: Foram utilizados como critérios de elegibilidade: artigos científicos relacionados a flare-ups em Endodontia, revisões de literatura e sistemáticas, estudos retrospectivos, ensaios clínicos randomizados, artigos completos e publicados nos últimos dez anos (2010 a 2020). As bases de dados empregadas para a busca foram: Pubmed, Google Acadêmico e Scielo. Resultados: Encontraram-se 2.138 estudos sobre fatores associados a flare-ups em Endodontia. Após aplicação dos critérios de elegibilidade, 20 trabalhos foram incluídos nesta pesquisa. A maior parte dos estudos demonstrou que flare-ups têm seu desenvolvimento principalmente influenciado por lesões químicas, mecânicas e microbianas na polpa ou nos tecidos perirradiculares. Conclusão: Existe uma relação entre polpas necróticas, presença de lesão periapical, dor prévia ao tratamento, retratamento endodôntico e presença de dor pós-operatória. A manutenção das condições assépticas, a conclusão do desbridamento biomecânico, o preparo psicológico dos pacientes, a determinação correta do comprimento de trabalho, evitar deixar o canal aberto e o uso de medicamentos intracanais são medidas de prevenção que devem ser adotadas durante a intervenção endodôntica, a fim de impedir o desenvolvimento de episódios dolorosos no pós-operatório.
Cisto dentígero em região anterior da mandíbula
Authors: Felipe Gomes Dallepiane  , Vanessa Cador Batu  , Marciele Cristiane Spanenberg Fuhr  , Anna Carolina Ceolin Milani  , Gabriela Caovilla Felin
Published: November 2022

O cisto dentígero é um cisto de origem odontogênica de desenvolvimento, normalmente encontrado em exames radiográficos de rotina, por ser assintomático. Sua patogênese está envolvida com o acúmulo de líquido entre a coroa do dente não irrompida e seu folículo. Objetivo: Relatar um caso clínico de paciente jovem com impactação dentária de canino inferior associado a um cisto dentígero, demonstrando planejamento e correto diagnóstico. Relato de caso: Paciente do sexo masculino, 15 anos, com queixas de atraso de erupção do canino inferior. Ao exame, apresentou ausência clínica do dente 33 e persistência do dente 73 com mobilidade. Radiograficamente, constatou-se o elemento 33 incluso e impactado com curvatura em ápice radicular, além de apresentar espessamento de folículo compatível com lesão cística. O plano de tratamento proposto foi remoção cirúrgica do dente e enucleação da lesão. Conclusão: A escolha do tratamento deve levar em consideração fatores como tamanho da lesão e sua localização com proximidade de estruturas anatômicas nobres. O tratamento cirúrgico mediante a exodontia do elemento dentário envolvido com a curetagem da lesão é o principal procedimento quando a ortodontia não é indicada.
Casual disclosure of an enlargement of the sella turcica during orthodontic treatment planning
Authors: Allan Abuabara  , Giuseppe V. Cruz  , Mário J. Nóbrega
Published: November 2022

Systemic disorders may be identified during dental care provision at oral and maxillofacial radiographs. We present a casual disclosure of an abnormal enlarged sella turcica with erosion of posterior clinoid process in an asymptomatic 32-year-old female. Although the diagnosis remains undetermined because no follow-up information was obtained from the referring clinician, possible options are discussed. The orthodontists and general practitioners must pay special attention when analyzing dental and maxillofacial images.
O auxílio concedido pela Casa-Hospício do Porto às crianças desprotegidas : (1915-1917)
Authors: Moreira Joana Filipa Cardoso
Published: November 2022

Considering the fact that, throughout the 19th and 20th centuries, there was a growing concern with children and the consolidation of a public system of assistance to unprotected minors, in this article we will seek to analyze the aid granted by Casa-Hospício do Porto to un protected children between 1915 and 1917. In this sense, from the heuristic point of view, we will study, concomitantly, issues of collective and individual dimension – that is, issues that are articulated with the functioning of the establishment, with the profile of the children assisted and with their journey in the institution. To achieve the intended purpose, we will scan the Entry Books that cover the alluded period of time, since the individual entries of all foster children received are recorded in there.
Crime e castigo : criminalidade judaica no reinado de D. João II
Authors: Marques Ana Maria Carvalho
Published: November 2022

Medieval criminality has been explored extensively since the twentieth century. Nevertheless, criminality committed by ethnic minorities has never played a major role in these works. Thus, our aim with this article is to make an intensive study of pardon letters issued at the request of Jews, during the reign of D. João II, in order to conclude if Jewish criminality has specific characteristics.
Filhos de Algo : Os Sás como alcaides-mores do Porto entre 1392 e 1449
Authors: Cardoso Hugo Filipe Pinto
Published: November 2022

This work seeks to analyze the relationships between the mayors belonging to the lineage of the Sás and the city of Oporto, utilizing the books of minutes corresponding to the period under study, we will also use separate documentation and diverse bibliography. We intend to understand how the condition of these nobles may have affected their relationship with the city of Oporto, famous for confronting the nobility several times. During the development of this study, we touched on several aspects, such as patronage networks and the lineage of the Sás.
Santa Casa da Misericórdia e Câmara Municipal em Arrifana de Sousa : vínculos entre as estruturas de poder entre 1741 e 1751
Authors: Mota Ana Catarina
Published: November 2022

The Misericórdias were, from their establishment, institutions under Portuguese Crown’s jurisdiction with great economic power and social prestige. Those factors let them become powerful and influential entities in the areas where they were established, attracting the most socially and economically prestigious social groups which, frequently, were also involved in the local political power. This essay will carry on a case study centered in Arrifana de Sousa (nowadays, Penafiel) in which, by intersecting data from primary sources, like Termos de Entrada e Aceitação, Termos de Posse e Eleição from the Misericórdia fond and the Livro de Registos da Câmara, we will try to check the existence of such kind of bonds between the local Misericórdia, established in 1509, and the local political power, between 1741 and 1751 — the first ten years of activity of this last structure of power in Arrifana de Sousa.
EFEKTIVITAS PENGGUNAAN TINY-SCANNER DALAM MODEL STAD TERHADAP HASIL BELAJAR PESERTA DIDIK KELAS XI.MIPA DI SMA NEGERI 9 YOGYAKARTA
Authors: Lasmanawati Ati
Published: November 2022

Penggunaan Tiny-Scanner dalam model STAD pada penelitian ini dilakukan karena kurangnya pemanfaatan aplikasi gadget dalam mengefektifkan proses pembelajaran di kelas, yang berdampak pada rendahnya hasil belajar matematika peserta didik. Penelitian jenis kuantitatif dengan metode quasi-eksperimen design tipe posstest-only control design, dilakukan pada peserta didik kelas XI.MIPA-4 (kelas eksperimen) dan kelas XI.MIPA-5 (kelas kontrol) untuk materi Transformasi Geometri Tahun Pelajaran 2018/2019. Tahapan penggunaan aplikasi Tiny Scanner dalam model STAD, yaitu 1) persiapan; 2) penyampaian informasi; 3) organisir peserta didik; 4) pemberian tugas; 5) membantu kerja kelompok dalam belajar; 6) menguji materi; 7) kuis; dan 8) penghargaan. Instrumen yang digunakan dalam penelitian terdiri dari lembar observasi, tes tertulis, dan tes praktek. Efektivitas penggunaan Tiny-Scanner dalam model STAD dilihat dari nilai rata-rata sikap peserta didik kelas eksperimen yang pada umumnya sudah mencapai predikat Sangat Baik (SB). Kompetensi pengetahuan nilai rata-ratanya sebesar 79,19 sudah melampaui KKM, dan nilai ini lebih tinggi dari kelas kontrol yang hanya sebesar 68,56. Capaian nilai rata-rata untuk kompetensi keterampilan sebesar 81,00 untuk kelas eksperimen dan kelas kontrol yang hanya sebesar 70,00. Berdasarkan hasil uji hipotesis pada taraf kesalahan α = 5%, n1 = 35, n2 -= 34, dk1 = 34, dan dk2 = 33 dengan nilai uji rata-rata pada kompetensi pengetahuan (thitung) adalah 3,109 dan ttabel = 2,033. Karena nilai thitung ttabel maka hasil ini uji hipotesis menunjukkan bahwa terdapat efektivitas penggunaan Tiny-Scanner dalam model STAD terhadap hasil belajar peserta didik di kelas XI.MIPA pada materi Transformasi Geometri Tahun Pelajaran 2018/2019.
BUDI PEKERTI MENJALIN PERSAHABATAN MELALUI UCAPAN DALAM SERAT SANASUNU KARYA R.Ng. YASADIPURA II
Authors: Nugroho Sigit
Published: November 2022

AbstrakSerat Sana Sunu adalah karya sastra Jawa yang ditulis oleh  R. Ng. Yasadipura II berisi ajaran-ajaran luhur untuk menjadi manusia yang utama.  Penelitian ini bertujuan untuk mengungkap nilai-nilai budi pekerti menjalin persahabatan melalui ucapan yang terkandung di dalam serat Sana Sunu. Penelitian ini menggunakan metode kualitatif. Sumber data naskah Serat Sana Sunu. Teknik pengumpulan data dengan baca catat.  Data yang didapat adalah data kualitatif berupa  teks Serat Sana Sunu karya R.Ng. Yasadipura II khususnya teks yang berkenaan dengan ajaran-ajaran menjalin persahabatan. Instrumen penelitian adalah peneliti sendiri (human instrument). Keabsahan data menggunakan teknik pembacaan yang berulang-ulang dan triangulasi. Adapun  analisis data menggunakan cara kualitatif. Hasil penelitian terhadap serat Sana Sunu menunjukkan bahwa di dalam menjalin persahabatan melalui ucapan diperlukan prinsip-prinsip yang harus diterapkan. Prinsip-prinsip tersebut adalah:  dapat menjaga rahasia, tidak sombong, menjauhi kefasikan, bicara penuh kebijaksanaan, tidak suka berdusta, dan tidak suka mencela.