bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of Mohr-Coulomb and hardening soil constitutive models for simulation of settlements in the Karkheh earth dam
Authors:   Shahrekord University, Iran, Samadi-Boroujeni Hossein , Haghshenas-Adarmanabadi Amir , Shayannejad Mohammad , Khabbaz Hadi ,   University of Technology Sydney (UTS)
Published: August 2023

This paper presents the settlement behaviour of Karkheh earth dam during its construction and operation stages. Karkheh is one of the largest earth dams in the world in terms of its reservoir capacity and body volume. The settlement of such a large body of soil can affect the performance of the dam elements and endanger downstream areas; should a breach or failure occur in the dam, more than two million people will be affected. It is crucial to know the settlement behaviour of this structure and use the existing results to predict its future settlements and calibrate the existing stress-strain models. For anticipation of dam settlement the measured displacement from the portable probe anchor magnets installed in the dam body are compared to the results of numerical simulations. The available data cover a period of 12 years including construction, and two material impounding and operation periods of the dam. The numerical analysis is performed in 2D plane-strain conditions and two material models are used, including Mohr-Coulomb (MC) and Hardening Soil (HS) models. The comparison between the calculation results and the measured vertical deformations in the dam site reveals that the accuracy of model for the deformations in the middle levels of dam is better than those of the crest for both applied material models in construction and impounding stages. The maximum settlement differences between computed and observed values are 0.05 m for MC model and 0.01 m for HS model. For the operation stage, the error of calculated settlements for the MC model is smaller; hence the results of this model might be more reliable for prediction of future dam settlements. The similar trends, obtained from both material models, exhibit the suitability of the model parameters used in the simulations.
Atividades do Núcleo de Apoio à Pesquisa e Produção Científica do curso de Fisioterapia do Centro Universitário Barão de Mauá em 2022
Authors: Regueiro Eloisa Maria Gatti , Vasconcelos Elaine Cristine Lemes Mateus , Vasconcelos Everaldo Encide , Papa Patricia Rodrigues Miziara , Narita Felipe Ziotti
Published: August 2023

O Núcleo de Apoio à Pesquisa e Produção Científica em Fisioterapia (NaPPFisio), do Centro Universitário Barão de Mauá (CBM), é dedicado ao fomento da produção científica de docentes vinculados ao curso, dispondo de palestras a fim de incentivar a produção científica e a formação continuada dos docentes.
A cink-oxid alternatívái a malacok takarmányozásában : Irodalmi összefoglaló
Authors: Hetényi Nikoletta
Published: August 2023

A malacok választás utáni hasmenése az állatorvosi költségek, a romló termelési mutatók és az esetleges elhullás miatt jelentős gazdasági kárt okozhat. A kórkép megelőzésére a sertéságazatban széles körben használták a nagy dózisú (2500–3000 mg/kg) ZnO-ot, amit azonban 2022. június 26. óta tilos alkalmazni az Európai Unióban, tehát a ZnO-ot tartalmazó állatgyógyászati készítmények engedélyeit visszavonták. Emiatt, továbbá a hasmenés kezelésére használt antibiotikumfelhasználás visszaszorítása érdekében előtérbe kerülnek az alternatív eszközként használható takarmánykiegészítők. A szerző szakirodalmi összefoglalójának célja ezen módszerek ismertetése a gyakorlati alkalmazhatóság szempontjából.
LCGC and ACS Subdivision on Chromatography and Separations Chemistry Survey 2023: What Skills Do New Analytical Chemistry Employees Need?
Authors: Grinias James P. , Smith Trevor I. , Kovarik Michelle L.
Published: August 2023

For this year’s career issue, LCGC North America teamed up with the American Chemical Society Subdivision on Chromatography and Separations Chemistry to ask the analytical chemistry community what skills new employees in the field need to succeed. In this report, we analyze the survey results and explore how they can inform the future of analytical chemistry curriculum development.
Sprzeciw wobec zabójstwa ks. Stanisława Streicha w świetle prasy końca lat trzydziestych XX wieku
Authors: Mueller Wojciech
Published: August 2023

Celem niniejszego opracowania jest ukazanie form społecznego sprzeciwu wobec zamordowania ks. Stanisława Streicha 27 lutego 1938 r. w kościele pw. św. Jana Bosko w Luboniu. Fakt zbrodni oraz męczeńskiej śmierci kapłana zaistniał na tle politycznym, światopoglądowym i społecznym w II Rzeczypospolitej. Ówczesna prasa, szeroko komentując morderstwo, stała się niezwykle cennym źródłem informacji na temat wydarzeń, które rozegrały się w Luboniu. Polskie artykuły prasowe końca lat trzydziestych XX wieku, pomimo odmiennych różnic w przedstawianiu zbrodni, zostały uznane jako materiał dowodowy w procesie beatyfikacyjnym Sługi Bożego, a przekonanie, że został zabity z nienawiści do wiary i oddał swoje życie Chrystusowi, pojawiło się już w chwili jego śmierci i w prostej linii zmierzało do rozpoczęcia procesu beatyfikacyjnego. Treści składające się na realizację opracowania w znacznej części uległy rozproszeniu i znajdują się w różnych bibliotekach i archiwach. Dlatego proces badawczy w opracowaniu został przeprowadzony metodą analityczno-syntetyczną. Synteza umożliwiła zestawienie i ujęcie materiału badanego w całość, odtworzoną na podstawie wcześniejszej analizy oraz pozwoliła na przebadanie źródeł pod kątem wybranego zagadnienia, ujętego w temacie pracy, wyciągnięcie konkluzji, a także udzielenie odpowiedzi na postawione dubia.
Obywatelstwo Unii Europejskiej. Uwarunkowania historyczne – prawne nadużycia i przestępstwa
Authors: Piotrowski Mirosław
Published: August 2023

Ustanowienie w Traktacie o Unii Europejskiej wspólnego obywatelstwa dla obywateli państw członkowskich tej organizacji, było kluczowym elementem przejścia do kolejnego etapu procesu integracji. Obywatelstwo UE było obywatelstwem drugim, po obywatelstwie krajowym i miało charakter „dodatkowy”. Stosowne zapisy w tej sprawie przeniesiono do Traktatu ustanawiającego Konstytucję dla Europy, a następnie do obowiązującego Traktatu z Lizbony. Przedstawiona jurydyczna konstrukcja, wzmocniona uzyskaniem osobowości prawnej przez UE, nie istniała dotychczas w historii stosunków międzynarodowych. Zgodnie z traktatami nadawanie obywatelstwa w poszczególnych państwach, należy do wyłącznej kompetencji ich władz krajowych. Okazało się, że wiele z nich uruchomiło programy „złotych paszportów” i „złotych wiz”, mające na celu sprzedaż obywatelstwa własnego kraju, a co za tym idzie sprzedaż obywatelstwa UE. To przyczyniało się do wzrostu korupcji, prania brudnych pieniędzy, itp., na obszarze UE. Nagłaśniane w mediach przykłady przyczyniły się do organizacji debat w PE oraz pobudziły KE do działania. Według ustaleń KE , w procederze tym brało udział, aż 21 krajów członkowskich Unii. KE jako strażniczka traktatów, zaczęła je dyscyplinować. W oparciu o art. TL, dotyczący zasady lojalnej współpracy UE z państwami członkowskimi,  wszczęła prawne procedury, o ich naruszenie, wobec Malty i Cypru, a ostrzegając Bułgarię. Zapowiedziano też podjęcie dalszych działań.
Reporting in the "new narmal". How the Covid-19 Pandemic Affected Journalistic Practice in the Philippines
Authors: Salvosa II Felipe F. , Esguerra Christian V.
Published: August 2023

The researchers sought to document the impact of the Covid-19 pandemic on Filipino journalists through a qualitative study. Thirty journalists were purposively selected to reflect the diversity of platforms (TV/radio, print, online), scope of coverage (national and local/regional), and region (Metro Manila, Luzon, the Visayas, and Mindanao). In-depth interviews were conducted using the guide developed by the Global Risk Journalism Hub (https://www.globalriskjournalismhub.com), an international research network of scholars from 35 countries. The main findings of the study covered the following areas: 1.) journalists’ views: key issues confronting the Philippines during the covid-19 crisis; 2.) reporting methods during the pandemic; 3.) personal and professional challenges encountered by journalists; and 4.) role perception of journalists. Despite the challenges posed by the pandemic, both to their personal and professional lives, and consistent with related studies, journalists interviewed went back to their moral obligation and sense of purpose, especially in a pandemic: to tell the truth by providing accurate information and context, and minimize harm to a suffering public.
Treatment of lymphedema, two methods compared: Ketogenic diet and Endospheres, Ketogenic diet and Vodder lymphatic drainage
Authors: Bellomo R.G , Buda R , Porreca A , Virgili E , Postacchini G , Bacci Pier Antonio , Saggini R , Barbato C
Published: August 2023

Lymphedema is a chronic disease with an evolutionary and often disabling nature, which represents an abnormal and excessive accumulation of lymphatic fluid on the interstitial side, both due to altered morphology of the lymphatic vessel and excessive lymph formation with difficulty in drainage. This condition is characterized by stasis of water and macromolecules, which, over time, transform the connective tissue into fibrous tissue. Unfortunately, it is a very widespread pathological condition. According to official data in Italy, there are about 40,000 cases per year, especially as a result of surgery, trauma, or radiotherapy such as secondary lymphedema and deriving from lymphatic channels or non-functional lymph nodes or in conditions of non-metabolic homeostasis. Unfortunately, despite the large-scale spread of lymphedema, information on this pathology is quite scarce, and the therapeutic alternatives offered to the patient are often limited and incomplete, forcing the patient to follow constant therapeutic paths. The main therapies are based on anti-inflammatory, vascular drugs, and physiotherapeutic treatments, based on various types of lymphatic drainage, first of all, the lymphatic drainage described by Vodder. It is known that the lymphatic system is a drainage tissue of the macromolecules produced by the cellular activities of the organism. However, it also acts as an important immune organ closely connected to the adipose and metabolic system, affected by the inflammatory processes caused by overweight, intestinal dysbiosis, and visceral obesity. For this reason, lifestyle advice and good nutrition are always associated with lymphatic drainage. One hundred female patients with lymphedema and lipolymphedema were followed by Prof. Bellomo who recommended a ketogenic diet; half were treated with traditional Vodder lymphatic drainage, the other with compressive microvibration method. Both groups maintained suitable compression stockings. The results obtained in the two different experimental groups highlighted the ability of the therapeutic combination between a ketogenic diet and Endosphere Therapy to offer stable results thanks to the draining and vascularizing actions, which are associated with the reduction of inflammatory processes caused by overweight and visceral fat.
HUBUNGAN ANTARA STATUS GIZI DENGAN KADAR GULA DARAH LANSIA DI DESA MANURUNGE, KABUPATEN BONE
Authors: Hasminindar Ichsan Trisutrisno , Nurdin Irda , Mustar  , Hasnidar
Published: August 2023

Lansia merupakan kelompok usia yang mengalami proses penuaan dan rentan terhadap penyakit. Bertambahnya jumlah lansia di Indonesia akan membawa pengaruh besar dalam pengelolaan kesehatan. Permasalahan kesehatan pada kelompok umur ini sangat erat kaitannya dengan masalah status gizi baik itu gizi kurang, gizi lebih dan obesitas. Selain masalah kekurangan gizi, masalah obesitas juga sering dialami oleh lansia karena aktivitas sudah berkurang sementara asupan makanan tidak dikurangi atau bahkan berlebihan. Kondisi ini dapat memicu timbulnya berbagai penyakit degeneratif, salah satunya diabetes melitus. Diabetes  Melitus  adalah penyakit yang disebabkan oleh adanya kelainan metabolik yang ditandai dengan  tingginya kadar gula darah. Penelitian    ini    bertujuan    untuk mengetahui   hubungan   antara status gizi dengan kadar gula darah Lansia di Desa Manurunge, Kabupaten Bone.  Penelitian  ini menggunakan  pendekatan cross sectional dengan jumlah  sampel 64 orang. Penentuan sampel menggunakan rumus uji hipotesis beda dua  proporsi. Teknik  analisis  data meliputi  analisis  univariat  dan  analisis  bivariat  dengan  uji chi square. Hasil  analisis  diketahui  dari  64 responden  ditemukan 53,1%  yang  memiliki status gizi normal, sedangkan yang berstatus gizi lebih 46.9%. Adapun responden yang memiliki kadar gula darah tinggi yaitu 56.2% , sedangkan yang normal 43,8%. Setelah dilakukan pengujian secara statistik diperoleh hasil hubungan yang signifikan antara status gizi dengan kadar gula darah lansia p=0.001 dengan OR =7.333 (2.350-22.884) artinya seseorang dengan status gizi lebih memiliki peluang memiliki kadar gula darah yang tinggi, sehingga berisiko  mengalami kejadian diabetes mellitus tipe 2 sebesar 7.333 kali dibanding yang memiliki status gizi yang normal
PENGARUH PENDIDIKAN KESEHATAN TERHADAP PENINGKATAN PENGETAHUAN REMAJA TENTANG PENYAKIT HIV/AIDS DI SMKS X JAKARTA
Authors: Nurlindawati  , Anggereni Kustia , Purnomo Babo Djimmy Heru , Yunita Tri
Published: August 2023

Abstract.  Adolescence is a productive age that is very vulnerable to contracting HIV-AIDS, because at that time adolescents experience high sexual urges and are always looking for information about sex, and the knowledge and information related to reproductive health they get is very lacking. Teenagers generally prefer to look for various sources of information they can get, such as accessing adult sites on the internet, trying to masturbate, making out or even having sex with their girlfriends. Health education plays an important role in increasing youth's knowledge and attitudes towards HIV-AIDS prevention. The purpose of this study was to determine the effect of health education on increasing adolescent knowledge about HIV/AIDS. The type of research used is qualitative with a pre-experimental design with one group pretest posttest. The results of this study indicated that there was an effect of health education on increasing adolescent knowledge about HIV/AIDS in class XII students of SMKS X Jakarta with the chi-square test results obtained p-value = 0.000.
PENGARUH KEBIASAAN KONSUMSI MINUMAN KEMASAN BERPEMANIS TERHADAP BERAT BADAN SISWA KELAS X SMK BINA SEHAT
Authors: Putri damayanti  , Rahmat Irwandi , Rezki
Published: August 2023

Currently, various types of drinks have been packaged in instant form to make it easier for consumers to enjoy various flavors of drinks. Packaged sweetened drinks are a type of drink that is dense in calories and high in sugar but low in nutrition. This research aims to see the influence of the habit of consuming packaged drinks in class X students of Bina Sehat Vocational School. This research is qualitative in nature with data collection using a questionnaire distributed to students. The results showed that the habit of consuming packaged beverages in class X students of Bina Sehat Vocational School was included in the rare category with an average body weight of 45.5 kg which was included in normal nutritional status.
STUDI INSILICO MYRISTICIN DARI MYRISTICA FRAGRANS SEBAGAI ANTIBAKTERI
Authors: Nurul Nurul Afriani Arif , Rahmat Irwandi , Wahid Abdul
Published: August 2023

Abstract. Antibiotics are a way to overcome the problem of disease in fighting infections caused by bacteria and are needed by humans in relation to the world of health. However, in the past year, many antibiotics spread have fewer effective results on human health. The objective of this research is to find the bioactivity of potential compounds from the Myristica fragrans plant which is thought to be able to be used as an antibacterial. Reverse docking study was performed using PyMOL software v1.7.4.5 (Schrodinger), PyRx 0.8 software, and SwissAdme Prediction. The results of this research indicate that the natural compound myristicin from the plant Myristica fragrans has the potential as an anti-bacterial drug with an affinity binding value of -5.2 only but is still low, compared with synthetic compound ampicillin which has an affinity binding value of -6.7.

 

Abstrak. Antibiotik merupakan salah satu cara untuk mengatasi permasalahan penyakit dalam melawan infeksi yang disebabkan oleh bakteri dan sangat dibutuhkan oleh manusia dalam kaitannya dengan dunia kesehatan. Namun, dalam satu tahun terakhir, banyaknya penyebaran antibiotik memberikan dampak yang kurang efektif terhadap kesehatan manusia. Tujuan dari penelitian ini adalah untuk mengetahui bioaktivitas senyawa potensial dari tanaman Myristica fragrans yang diduga dapat digunakan sebagai antibakteri. Studi reverse docking dilakukan dengan menggunakan software PyMOL v1.7.4.5 (Schrodinger), software PyRx 0.8, dan SwissAdme Prediction. Hasil penelitian ini menunjukkan bahwa senyawa miristisin alami dari tanaman Myristica fragrans mempunyai potensi sebagai obat anti bakteri dengan nilai afinitas pengikatannya hanya -5,2 namun masih rendah dibandingkan dengan senyawa sintetik ampisilin yang mempunyai nilai afinitas pengikatan. dari -6,7.
Modelling the process of assessing the corruption orientation of regulatory legal acts
Authors: Losev Mikhaylo , Holovko Oleksandra , Skorin Yuriy
Published: August 2023

In the conditions of growing requirements for methods and means of combating negative phenomena of society, prevention and deterrence of corrupt actions of officials by creating new and editing old normative legal acts can significantly limit the development of such offenses and have a positive effect on the economic state of the country. The urgent task is to develop simple and effective methods of modelling and assessing the level of corruption orientation of normative legal acts. The paper examines the problem of quantitative assessment of the negative phenomenon of corrupt activity of officials, which can be stimulated by regulatory and legal acts. The purpose of the article was to improve the methods and techniques of analysis of the process of assessing the quality of normative legal acts by modelling their corruption orientation. The methods of fuzzy set theory and fuzzy logical inference, as well as the methods of probability theory are used in the process of modelling the quantitative assessment of the level of corruption oriented legal acts. The proposed approach makes it possible to simultaneously take into account separate criteria that are based on subjective assessments and have uncertainties of various natures, and are also characterized by a large number of them with their inequality and antagonism. At the same time, the modelling process provides the possibility of using both a clear and unclear representation of the initial data, reduces the influence of subjectivity of expert evaluation factors of a heuristic nature. There is no need to determine the weight of each individual factor when forming a global criterion for deciding on the level of corruption orientation of a normative legal act. On the basis of the obtained values of the global criterion, a decision is made to choose one or another variant of the normative legal act. The paper examines the stages of implementation of the proposed approach to assessing the level of corruption orientation of the normative legal act on the reclamation of forestry lands disturbed as a result of amber mining. The results of the work can be useful in the development of drafts of new legislation, as well as for researchers of methods of control and management of complex technical and economic systems
Genetic diversity and phylogenetic relationship of Angus herds in Hungary and analyses of their production traits
Authors: Márton Judit , Szabó Ferenc , Zsolnai Attila , Anton István
Published: August 2023

Objective: This study aims to investigate the genetic structure and characteristics of the Angus cattle population in Hungary. The survey was performed with the assistance of the Hungarian Hereford, Angus, Galloway Association (HHAGA).Methods: Genetic parameters of 1,369 animals from 16 Angus herds were analyzed using the genotyping results of 12 microsatellite markers with the aid of PowerMarker, Genalex, GDA-NT2021, and STRUCTURE software. Genotyping of DNA was performed using an automated genetic analyzer. Based on pairwise identity by state values of animals, the Python networkx 2.3 library was used for network analysis of the breed and to identify the central animals.Results: The observed numbers of alleles on the 12 loci under investigation ranged from 11 to 18. The average effective number of alleles was 3.201. The overall expected heterozygosity was 0.659 and the observed heterozygosity was 0.710. Four groups were detected among the 16 Angus herds. The breeders’ information validated the grouping results and facilitated the comparison of birth weight, age at first calving, number of calves born and productive lifespan data between the four groups, revealing significant differences. We identified the central animals/herd of the Angus population in Hungary. The match of our group descriptions with the phenotypic data provided by the breeders further underscores the value of cooperation between breeders and researchers.Conclusion: The observation that significant differences in the measured traits occurred among the identified groups paves the way to further enhancement of breeding efficiency. Our findings have the potential to aid the development of new breeding strategies and help breeders keep the Angus populations in Hungary under genetic supervision. Based on our results the efficient use of an upcoming genomic selection can, in some cases, significantly improve birth weight, age at first calving, number of calves born and the productive lifespan of animals.
Treatment effect of remdesivir on the mortality of hospitalised COVID-19 patients in Switzerland across different patient groups: a tree-based model analysis
Authors: Estill Janne , Venkova-Marchevska Plamenna , Günthard Huldrych F. , Botero-Mesa Sara , Thiabaud Amaury , Roelens Maroussia , Vancauwenberghe Laure , Damonti Lauro , Heininger Ulrich , Iten Anne , Schreiber Peter W. , Sommerstein Rami , Tschudin-Sutter Sarah , Troillet Nicolas , Vuichard-Gysin Danielle , Widmer Andreas , Hothorn Torsten , Keiser Olivia
Published: August 2023

AIMS OF THE STUDY: Remdesivir has shown benefits against COVID-19. However, it remains unclear whether, to what extent, and among whom remdesivir can reduce COVID-19-related mortality. We explored whether the treatment response to remdesivir differed by patient characteristics.
METHODS: We analysed data collected from a hospital surveillance study conducted in 21 referral hospitals in Switzerland between 2020 and 2022. We applied model-based recursive partitioning to group patients by the association between treatment levels and mortality. We included either treatment (levels: none, remdesivir within 7 days of symptom onset, remdesivir after 7 days, or another treatment), age and sex, or treatment only as regression variables. Candidate partitioning variables included a range of risk factors and comorbidities (and age and sex unless included in regression). We repeated the analyses using local centring to correct the results for the propensity to receive treatment.
RESULTS: Overall (n = 21,790 patients), remdesivir within 7 days was associated with increased mortality (adjusted hazard ratios 1.28–1.54 versus no treatment). The CURB-65 score caused the most instability in the regression parameters of the model. When adjusted for age and sex, patients receiving remdesivir within 7 days of onset had higher mortality than those not treated in all identified eight patient groups. When age and sex were included as partitioning variables instead, the number of groups increased to 19–20; in five to six of those branches, mortality was lower among patients who received early remdesivir. Factors determining the groups where remdesivir was potentially beneficial included the presence of oncological comorbidities, male sex, and high age.
CONCLUSIONS: Some subgroups of patients, such as individuals with oncological comorbidities or elderly males, may benefit from remdesivir.
Über Moralisierung, oder: Wir, die Guten
Authors: Knobloch Clemens
Published: August 2023

Der Beitrag umreißt die Konturen moralisierender rhetorischer Techniken in der (medien-)öffentlichen Kommunikation. Moralisierung, so die These, erfüllt in der Gegenwart eine vollkommen andere Funktion als moralische Normen in traditionellen Gesellschaften. Moralisierung erschwert öffentlichen Dissens, wertet den Sprecher auf und improvisiert lose Wertegemeinschaften. Da die faktische gesellschaftliche Integration weitgehend über moralfreie institutionelle Zwänge (Märkte etc.) geregelt ist, wird Moralisierung zu einer freien rhetorischen Ressource.
The Mediating Role of Parenting Styles in the Relationship Between Family Adaptability and Cohesion and Cyberbullying in Adolescents
Authors: Najjari Ensiyeh , Ashouri Ahmad , Zahedi Komeil , Gharree Banafshe
Published: August 2023

Background: Excessive use of cell phones in adolescents is associated with injuries and behavioral deviations. Cyberbullying is one of these behavioral deviations which involves deliberate and repeated aggression. Family and parenting factors are considered to have an essential role in cyberbullying. Among these factors, the cohesion and flexibility of the family have garnered considerable attention. Objectives: The present study examined the relationship between family adaptability, cohesion, and cyberbullying and the mediating role of parenting styles in this relationship. Materials and Methods: Cross-sectional design and structural equation modeling (SEM) were used in this study. The statistical population included students using mobile phones in Tehran. A sample of 220 students was selected via convenience sampling. The Family Adaptability and Cohesion Evaluation Scales, Cyber-Bullying/Victimization Experiences Scale, and the Parental Authority Scale were used to collect data. Statistical data analysis was done using the Pearson correlation test and structural equation path analysis in SPSS 26 and AMOS 26. Results: The results showed that There was a significant correlation between family cohesion and cyberbullying (r =- 0.246) (P < 0.01), family adaptability and cyberbullying (r = -0.167) (P < 0.01), family adaptability and cohesion and parenting styles (r = 0.433) (P < 0.01), authoritarian, indulgent, authoritative parenting style and cyberbullying (r = 0.289) (r = 0.124) (r = -0.143) (P < 0.01). These direct and indirect effects were created through the mediation of parenting styles. Conclusions: Generally, the results showed that family adaptability and cohesion significantly negatively correlate with cyberbullying. The model showed family adaptability and cohesion, and cyberbullying did not have a direct relationship. However, perceived parenting styles can play a mediating role in this relationship.
Gender Disparities in Ankylosing Spondylitis: An Algerian Retrospective Analytical Cohort Study
Authors: Beldja Nassima Farah , Noria Harir , Ghariani Fathi , Zemri Khalida , Ouali Siheme , Sellam Feriel , Nadji Zouaoui , Sehimi Amel , Bensaber Ouassini , Mahieddine Asmaa
Published: August 2023

Background: Ankylosing spondylitis (AS) is an inflammatory disease that can impair function and lower quality of life, which causes spinal bone fusion and new bone production. Several studies have been done on the differences in damage between women and men. Objectives: This study aimed to assess the differences between men and women with AS regarding clinical characteristics, structural damage, and treatment used by Algerian patients. Methods: In this study, 292 patients diagnosed with AS at the Hassani Abdelkader Hospital Rehabilitation Department of Sidi Bel Abbes Region between 2018 and 2021 were enrolled. The studied parameters were age, disease duration, age at disease onset, morning stiffness, joint involvements, laboratory data, disease activity, and treatments. All data were processed and analyzed via Excel and SPSS 20.0 (Statistical Package for the Social Sciences, IBM Corporation, Chicago, IL, August 2011). Results: We assessed 166 females and 126 males. The mean age at disease onset was 31.69 ± 10.675 vs. 30.38 ± 10.250 years, and morning stiffness duration was 26.08 ± 26.977 vs. 23.80 ± 26.529 minutes in females and males, respectively. Positive HLA-B27 was noted more in 71.9% of women and 69.6% of men. Also, the female group suffered more from their lumbar (100%) and high inflammation (83.8% elevated erythrocyte sedimentation rate (ESR) and 59.9% positive C-reactive protein (CRP)) rather than females who suffered from a long disease duration (7.28 ± 4.867 vs. 6.74 ± 3.584). Peripheral joints were primarily affected in males than females (knees involvement: 26.4% vs. 3.6% and hips involvement: 69.6% vs. 3%, respectively). In addition, high disease activity was more noted in men (52.8% vs. 41.9%, respectively). The most noted comorbidities, including uveitis, psoriasis, and diabetes, affected more females than males (40% vs. 29.9%, 4.8% vs. 2.4%, and 2.4% vs. 1.2%, respectively). Concerning the treatment, men used more sulfasalazine than women, 86.4% vs. 76%, while women used more Humira than men (88.6% vs. 74.4%, respectively). Conclusions: According to our findings, women had a higher inflammation rate and more damage in their lumbar, requiring more sulfasalazine and Humira treatment than men who suffered from their peripheral joints and higher disease activity.
Subaltern voices from the sertão : cultural history of broadside ballad in Brazil
Authors: Březinová Kateřina
Published: August 2023

This paper analyzes the role of cordel – the Brazilian contribution to the global tradition of the broadside ballad – as a reservoir of cultural memory of the Nordeste, the region where cordel took root in Brazil. Cordel is at once perceived as a repertoire of representations, images, and meanings that have shaped messages on social order. The focus here is on transformations that have occurred in cordel titles over time and, in particular, how gender and ethnicity have been represented in cordel texts during different periods and locations in a region that, even now, has been characterized by latifundism, the absence of the state, and abysmal social inequalities. To this end, the examination of cordel titles by José Francisco Borges (1935), Jarid Arraes (1991), and Auritha Tabajara (1980) in this context is grounded in a cultural studies framework. Among other perspectives, we engage with the question posed by Spivak to highlight the cordel as a venue in which the subaltern voices of the colonized and otherwise marginalized segments of Brazil's population have expressed themselves historically until the present. Whereas cordel traditionally represented a space in which the voices and concerns of ordinary Brazilians from the rural hinterland found their way into the public arena, new possibilities of publishing cordel post-2000 have opened it up to new narratives from the otherwise silenced actors of Brazilian society and history, including female authorship, and Afro-Brazilians and the Indigenous as protagonists of their own representation. This paper concludes by pointing to how cordel has been notably successful in accommodating Brazil's diverse social realities. Its narratives now speak in the multiple voices of the sertão, thus inviting its readership to rethink Brazil's cultural history, historical memory, and symbolic imaginaries.
Songs about St. John of Nepomuk from the 17th to the 19th century (especially broadside ballads)
Authors: Ivánek Jakub
Published: August 2023

This paper focuses on St. John of Nepomuk, the most popular saint of the Czech Baroque period, and his hymnography, which constitutes the largest group of songs in the entire Baroque hymnography from the Czech lands, whether in Czech or German. The study is dedicated not only to analysing the song material from the perspective of literary history (leitmotifs, other frequent motifs, metaphors and terms, song genres, forms of narration) but also to seeking relations between the songs and piety itself. Songs about St. John of Nepomuk, preserved mainly as broadside ballads, were in fact closely connected to the religious services performed during the May feasts in Prague and in front of his statues and chapels, which were spreading across the country from the beginning of the 18th and far into the 19th century. My research is based on 328 gathered songs, of which 201 have so far been analysed in more detail.
Peter of Provence and fair Maguelonne : from a French mediaeval romance to a Czech broadside ballad
Authors: Kotšmídová Alena
Published: August 2023

This paper deals with the Czech broadside ballad about fair Maguelonne and Peter of Provence and its origins in a late mediaeval French prose romance, subsequently translated into German and Czech. Some basic information about the romance and an outline of its most important features, and those of the two translations, help put the broadside ballad into its literary and historical context. The main focus is, of course, on the broadside ballad itself, i.e., on presenting the preserved copies, describing the formal aspects of the work, and comparing the plot of the ballad with the plot of the Czech translation of the romance. Keeping in mind the previous versions of the story permits us not only better to understand the specificity of the broadside ballad, but, at the same time, to identify some of the modifications made by the author of the ballad as expressions of wider ongoing processes.
EXAIT: Educational eXplainable Artificial Intelligent Tools for personalized learning
Authors: Ogata Hiroaki , Flanagan Brendan , Takami Kyosuke , Dai Yiling , Nakamoto Ryosuke , Takii Kensuke
Published: August 2023

As artificial intelligence systems increasingly make high-stakes recommendations and decisions automatically in many facets of our lives, the use of explainable artificial intelligence to inform stakeholders about the reasons behind such systems has been gaining much attention in a wide range of fields, including education. Also, in the field of education there has been a long history of research into self-explanation, where students explain the process of their answers. This has been recognized as a beneficial intervention to promote metacognitive skills, however, there is also unexplored potential to gain insight into the problems that learners experience due to inadequate prerequisite knowledge and skills that are required, or in the process of their application to the task at hand. While this aspect of self-explanation has been of interest to teachers, there is little research into the use of such information to inform educational AI systems. In this paper, we propose a system in which both students and the AI system explain to each other their reasons behind decisions that were made, such as: self-explanation of student cognition during the answering process, and explanation of recommendations based on internal mechanizes and other abstract representations of model algorithms.
The Influence of Interest Rates and Inflation on the Yield to Maturity of Government Bonds Listed on the Indonesia Stock Exchange for the 2019-2021 Period
Authors: Syayidati Alfi Zahroh  , Hartono  , Yuliasnita Verlandes
Published: August 2023

This research aims at determining the impact of interest rates and inflation on government bond yields to maturity. This type of research using quantitative method. Non-probability sampling technique with kind of saturated samples was used for the selection of research samples. The population of this research is government bond with fixed series code listed on the Indonesia Stock Exchange in 2019-2021.The analytical method used by multiple linear regression analysis method is done by SPSS 22. One of the conditions must use the classic assumption test to get a good regression. This study uses secondary data obtained from the Indonesia Stock Exchange. This study uses quarterly data from 2019-2021. The result of this research is that interest rates and inflation together affect bond yields to maturity. Interest rate and inflation variables has positive significant effect on the government bond's yield to maturity.
Penerapan Pembelajaran Kitab Tuhfatul Athfal dalam Meningkatkan Kefasihan Membaca Al-Qur’an Santri
Authors: Mulki Muhammad Ilham Maulana , Kosim Ahmad Mulyadi , Alfaien Noor Isna
Published: August 2023

The objectives of this study are to find out whether the application of learning the Book of Tuhfatul Athfal can improve the fluency of reading the Qur'an of students, to find out how the application of learning the Book of Tuhfatul Athfal in the Islamic Boarding School of the Qur'an Al-Furqon Bogor, to determine the supporting and inhibiting factors in improving fluency in reading the Qur'an students of the Al-Qur'an Islamic Boarding School Al-Furqon Bogor. The method used in this study is a qualitative method with a descriptive approach, this research data collection technique uses observation, documentation and interview techniques. The results showed that. the purpose of studying the book of tuhfatul athfal at the Al-Qur'an Al-Furqon Islamic Boarding School is to keep the tongue to avoid mistakes when reading the Qur'an and avoid changing the meaning when reading the Qur'an. Efforts to improve fluency in reading the Qur'an are carried out by the Al-Qur'an Al-Furqon Islamic Boarding School starting at the boarding school entrance stage, namely by testing the reading of the Qur'an which aims to be able to classify new students in its Qur'an class. Supporting factors are teachers who are competent in their fields, obedient students, facilities and infrastructure to support learning, and parents who support their children. Inhibiting factors are learning time that is too narrow, students who do not obey, and interest and willingness in students or students.
A Reassessment of the Impact and Significance of Social Media to Pathology
Authors: Chen Stephanie J.T. , Samuelson Megan I. , Rajan KD Anand
Published: August 2023

Context

Social media (SM) use in pathology and medicine today is widespread, receives active advocacy, and is said to bring a host of benefits. In latter days, the harmful effects of SM have received attention, but they have yet been followed by greater encouragement of professionalized SM usage. SM use in medicine has seen adoption in parallel to its general ascendancy, even though the platforms are products with purposes misaligned with the practice of medicine.

Objective

To (1) characterize premises and forces that propel professional SM platform adoption and use, and (2) examine wide-ranging literature, both medical and nonmedical, that substantiates the premises and to find counteracting perspectives and evidence.

Data Sources

Review of the literature using relevant keyword searches in PubMed, Google Scholar, Dimensions, and Web of Science for articles that study/describe professional SM use in pathology and medicine. Additionally, we examined business, technology, and social sciences literature and high-quality gray literature (newspapers, books, blogs) that addressed questions in relation to the topic of professional SM adoption.

Conclusions

We identified 6 major premises as motivators of professional SM use and highlight significant counteracting factors. We conclude that the harms of professionalized SM use have not been fully considered in the medical literature and that a change in direction and the creation of new communication platforms would be beneficial.
New Entities and Concepts in Salivary Gland Tumor Pathology: The Role of Molecular Alterations
Authors: Seethala Raja R.
Published: August 2023

Context.—

Salivary gland tumors are rare tumor types for which the molecular understanding has resulted in a rapid expansion and shuffling of entities. These changes are reflected in the 5th edition World Health Organization Classification of Head and Neck Tumours (WHO 5th edition), although many nuances still remain.

Objective.—

To review how molecular alterations have helped recategorize, justify, and reinstate entities into our lexicon as well as defining interrelationships between categories, new entities, and subtypes. Furthermore, newer theranostic applications to molecular phenotype will be summarized.

Data Sources.—

World Health Organization Classification of Head and Neck Tumours (WHO 3rd through 5th editions), literature review, and personal and institutional experience.

Conclusions.—

Molecular alterations have helped reclassify, retain, and create new categories by augmenting rather than replacing standard criteria. Key entities that have emerged include sclerosing polycystic adenoma, microsecretory adenocarcinoma, and mucinous adenocarcinoma. Molecular phenotypes solidify the range of morphology in established entities such as mucoepidermoid carcinoma and facilitate connectivity between entities. Molecular characteristics now allow for targeted therapeutic approaches for secretory carcinoma and adenoid cystic carcinoma.
Correlation of In Situ HER2 RNA Expression With HER2 Immunohistochemistry and Fluorescence In Situ Hybridization Categories in Breast Cancer
Authors: Tseng Yu-Fen , Li Yu-Chia , Lee Yi-Hsuan , Hu Hsiang-We , Zhang Man-San , Hung Tze-Chun , Lien Huang-Chun
Published: August 2023

Context.—

RNA sequencing study has demonstrated that human epidermal growth factor receptor 2 (HER2) RNA levels influence anti-HER2 therapeutic efficacy. However, in situ HER2 RNA expression (isHRE), which evaluates HER2 RNA expression in tissue, has remained unclear in breast cancers (BCs) of various HER2 immunohistochemistry (IHC)/in situ hybridization (ISH) categories.

Objective.—

To correlate isHRE with all HER2 IHC/fluorescence ISH (FISH) categories in BC.

Design.—

Formalin-fixed, paraffin-embedded tissue sections from 259 BCs, covering all IHC/FISH categories, were analyzed for isHRE by RNAscope.

Results.—

We validated HER2 RNAscope scoring as a semiquantitative method to evaluate isHRE and demonstrated significantly higher RNAscope scores in IHC 3+ than in IHC 2+ cases, and in IHC 2+ than in IHC 0/1+ cases. Among the 5 IHC 2+/FISH groups, group 1 (G1) cases had the highest scores. The scores in G3 cases were higher than those in G2, but not significantly different from those in G4 and G5. G4 cases had significantly higher scores than those in G2. Higher HER2 copy numbers and HER2:CEP 17 (centromere 17) copy number ratios were significantly correlated with higher isHRE in G1 cases, but not in G2 to G5 cases. RNAscope scores were significantly lower in HER2-negative (IHC 0) than in HER2-low (IHC 2+/FISH− and IHC 1+) BCs but were not different between IHC 0 and 1+ BCs when analyzed separately.

Conclusions.—

We demonstrate the HER2 RNA expression status among BCs of various HER2 IHC/FISH categories in tissue. Such information may be relevant for anti-HER2 treatment decisions considering the role of HER2 RNA expression in predicting anti-HER2 therapeutic efficacy.
สมบัติเชิงหน้าที่ของโปรตีนจากมะพร้าวที่ดัดแปรด้วยวิธีดีแอมิเดชันโดยใช้เอนไซม์โปรตีนกลูตามิเนส
Authors:   , คุณารยกุล สุพิชชา
Published: August 2023

มะพร้าวเป็นพืชเศรษฐกิจที่มีการนำมาแปรรูปเป็นผลิตภัณฑ์เพื่อบริโภคได้หลากหลาย เช่น กะทิ และน้ำมันมะพร้าว ซึ่งในกระบวนการผลิตน้ำมันมะพร้าวจะนำกะทิมาแยกส่วนของน้ำมันออก และเหลือหางกะทิไว้ โดยพบว่าหางกะทิจะมีสัดส่วนของโปรตีนที่สูงขึ้นเนื่องจากมีการแยกส่วนของไขมันออกไปจึงสามารถนำส่วนของหางกะทินี้มาสกัดโปรตีนต่อได้ แต่โปรตีนที่สกัดได้มีมักข้อจำกัดในการนำไปใช้ เช่น มีความสามารถในการละลายในสภาวะกรดอ่อนต่ำ เป็นต้น งานวิจัยนี้มีวัตถุประสงค์เพื่อศึกษาสภาวะที่เหมาะสมในการดัดแปรโปรตีนจากมะพร้าวโดยใช้เอนไซม์ protein-glutaminase (PG) และสมบัติเชิงหน้าที่ของโปรตีนจากมะพร้าวที่ถูกดัดแปร โดยสกัดโปรตีนจากหางกะทิที่เหลือทิ้งจากอุตสาหกรรมการผลิตน้ำมันมะพร้าวด้วยวิธีการตกตะกอนโปรตีนที่จุด isoelectric point (pH = 3.9) และหาสภาวะในการดัดแปรด้วย response surface methodology (RSM) โดยเลือกสภาวะที่เหมาะสมคือมีค่า degree of deamidation (DD) สูง (>30 %) และมีค่า degree of hydrolysis (DH) ต่ำ (<5 %) พบว่าสภาวะที่เหมาะสมในการดัดแปรโปรตีนจากมะพร้าวด้วยเอนไซม์ PG คือ อัตราส่วนระหว่างปริมาณเอนไซม์ต่อปริมาณโปรตีนเป็น 36 U/g protein, อุณหภูมิ 50oC และ pH = 7 เมื่อดัดแปรโปรตีนด้วยสภาวะดังกล่าวที่ระยะเวลาต่าง ๆ กัน (15 min, 6 และ 12 h) เพื่อนำมาศึกษาสมบัติเชิงหน้าที่ได้แก่สมบัติการละลาย ความสามารถในการอุ้มน้ำและน้ำมัน ความสามารถในการเกิดอิมัลชัน และสมบัติการเกิดโฟม พบว่าสมบัติการละลายที่ pH = 3  มีค่าเพิ่มขึ้นอย่างมีนัยสำคัญเมื่อเทียบกับตัวอย่างควบคุมที่ไม่ผ่านการดัดแปรด้วยเอนไซม์ (p≤0.05) ในขณะที่ pH = 5 ไม่มีความแตกต่างกัน (p>0.05) ส่วน pH = 7 มีค่าลดลงในตัวอย่างที่ถูกดัดแปรเป็นเวลา 15 min และ 6 h เมื่อพิจารณาความสามารถในการอุ้มน้ำและน้ำมัน พบว่าทุกตัวอย่างไม่มีความแตกต่างกัน (p>0.05) เมื่อเทียบกับตัวอย่างควบคุม สำหรับสมบัติการเกิดอิมัลชัน พบว่าค่า emulsifying activity index (EAI) ของโปรตีนที่ผ่านการดัดแปร 15 นาที มีค่าลดลงอย่างมีนัยสำคัญ (p≤0.05) แต่โปรตีนที่ผ่านการดัดแปรเป็นเวลา 6 และ 12 h ไม่มีความแตกต่างกับตัวอย่างควบคุม (p>0.05) ค่า emulsifying stability index (ESI) ของโปรตีนที่ผ่านการดัดแปรทุกตัวอย่างมีค่าเพิ่มขึ้นอย่างมีนัยสำคัญเมื่อเทียบกับตัวอย่างควบคุม (p≤0.05) และเมื่อพิจารณาสมบัติการเกิดโฟม พบว่าตัวอย่างโปรตีนที่ผ่านการดัดแปรมีค่า foaming capacity (FC) สูงขึ้น  (p≤0.05) แต่ foaming stability (FS) มีค่าลดลง (p≤0.05) molecular weight distribution ของโปรตีนที่ผ่านการดัดแปรมีโมเลกุลขนาดเล็กเพิ่มขึ้น และองค์ประกอบของกรดอะมิโนของโปรตีนมะพร้าวที่ผ่านการดัดแปรมีลักษณะคล้ายคลึงกับตัวอย่างโปรตีนที่ไม่ผ่านการดัดแปร
Assessment of stressful life events for patients with substance abuse in Baghdad city
Authors: Shakhat Ali , Hashim Mushatq
Published: August 2023

Objective: The present study aims to assess the stressful life events for patients with substance abuse in Baghdad city.Methodology: A descriptive study was carried out at (Baghdad teaching hospital and Ibn-Rushed Psychiatric hospital).Starting from 1st of December 2012 to 3rd of July 2013, A non-probability (purposive) sample of 64 patients thatdiagnosed with substance abuse, the data were collected through the use of semi-structured interview byquestionnaire, which consists of three parts sociodemographic data, medical information, and Life events scaleconsists of 49-items distributed to six domains including, family and social domain, health domain, security, legal andcriminal domain, work and school domain, financial domain, and change of residence domain. A pilot study wascarried out to determine the questionnaire reliability through the use of (Cronbach alpha). Validity of the instrumentwas established through penal of (13) experts. Data was analyzed by application of descriptive and inferentialstatistical methods.Results: The study findings revealed that all sample (100%) are males, and about half of sample were at age (20-29)years, (50.8%) of them had completed primary school, married, unskilled worker, and more than two third- of themwere living in urban area. Health domain and family and social domain had more effects on patients than otherdomains.

Recommendations: Increase the individual awareness about management of the stressful life events to decrease theimpact of life events upon their Psychological health
Prevalence of obesity among adolescents at secondary schools in Kirkuk city
Authors: Danok Abas , Ghanem Eqbal
Published: August 2023

Objective: to identify the secondary school adolescent's obesity, and to find out the relationship betweenadolescents obesity characteristics and their family history.Methodology: A cross-sectional study was carried out among 537 adolescents (270 boys and 267 girls) aged 12-15years selected by means of a multistage stratified random sampling technique.Results: the prevalence of obesity among adolescents was 22.3%. (55.8%) of the obese adolescents were male,(42.5%) their age is (13) years old, and (79.2%) of them coming from middle level of socio economic status score.There are a significant relationship between obese adolescents and their family history of obesity which indicatedthat obese father, and obese brother /sister (0.000, 0.037, & 0.000) respectively have a highly significantrelationship with adolescents' obesity.Recommendation: Intervention programs focusing on promoting changes in lifestyles, food habits and increasingphysical activity need to be implemented at the earliest stage of children life