bluuebunny/crossref_metadata_2025 huggingface dataset:
Self-regulation system of continual improvement of quality and efficiency in higher education: A case of Ukraine
Authors: Velychko Oleksandr , Khalatur Svitlana , Bondarchuk Nataliia , Bahorka Mariia
Published: August 2022

Nowadays, the procedures for stimulating the improvement of the quality of higher education in Ukraine are mainly based on periodic expert evaluations. Besides, existing metrics of university efficiency are usually imperfect due to the frequent negative effects of Campbell’s Law and Goodhart’s Law. In addition, the war significantly limited resources for external quality assurance of educational programs. Given this, the aim of this paper was to develop a methodology for an additional self-regulation system of continual improvement of the quality and efficiency of educational activities of Ukrainian universities. The study is based on the advantages of the quantitative approach, measurement methods, and algorithmization in the management system of higher education. As a result, key indicators for the formation of national rankings have been developed by different segments. Moreover, the study elaborated algorithms and mechanisms to constantly encourage higher education institutions to improve quality and efficiency. The paper proposes preventive procedures to reduce the negative effects of unfair achievement of key performance indicators. The result of applying the methodology is additionally acquired or partially lost by the university the volume of license rights for the training of specialists in the current year. This will help curb the process of mass education with a low level of quality. In addition, the proposed system will balance the weaknesses of the accreditation expertise procedure, as well as actively stimulate the independent striving of each educational program for sustainable development and continual progress.
Acknowledgment To the Armed Forces of Ukraine (https://www.mil.gov.ua/) and the democratic world (https://bit.ly/3BLtuem) for the protection of the future of the Ukrainian State and its people. To the National Agency for Higher Education Quality Assurance for the possibility to take part in accreditation expertise and consulting evaluation of educational programs in universities of Ukraine (https://en.naqa.gov.ua/). Also, the appearance of this alternative idea was facilitated by the declared goal of the World Bank project “Ukraine Improving Higher Education for Results” (ID P171050), namely: to improve the efficiency, conditions for quality, and transparency in Ukraine’s higher education system (https://bit.ly/3vpx2iM).
 
Waqf Land Certification Postponement for Place of Worship Due to the Obscurity of the Toll Road Expansion Project (Re-overview of Gustav Radbruch's Three Basic Legal Values Theory)
Authors: Emha Zidney Ilma Fazaada , Silviana Ana , Musahadi Musahadi
Published: August 2022

Data from the Ministry of ATR/BPN shows that most waqf lands have legal certainty problems. This article wants to look at the case of delaying the certification of waqf land for the Baitussalam Mosque in Semarang City due to the unclear toll road expansion project. The discussion is related to Gustav Radbruch's theory of three fundamental legal values. This paper uses an empirical juridical approach with a qualitative descriptive-analytical research specification. Data were obtained through interviews with several key informants and supported by legal materials obtained from literature studies. The results showed that the delay in certifying the waqf land of Baitussalam Mosque at the Semarang City Land Office was due to legal concerns by residents if the land was affected by the expansion of the toll road project. This article proves that Gustav Radbruch's standard priority teachings, which prioritize justice over expediency and legal certainty, are irrelevant and not ideal. The case of Baitussalam Mosque places legal certainty through waqf land certification as a top priority that must be carried out. Thus, this study confirms the teaching of casuistic priority in the theory of modern legal goals.
Representaciones sociales del género masculino. Un estudio entre jóvenes bachilleres de Tepatitlán, Jalisco
Authors:   Universidad de Guadalajara, Castellanos Gutiérrez Christian Lorenzo , Zamora Betancourt María del Rosario ,   Universidad de Guadalajara, Caldera Montes Juan Francisco ,   Universidad de Guadalajara, Reynoso González Oscar Ulises ,   Universidad de Guadalajara
Published: August 2022

El presente trabajo tuvo por objetivo reconocer la estructura de las representaciones sociales en torno al género masculino por parte de hombres jóvenes. La muestra quedó conformada por 177 bachilleres, todos ellos habitantes de la localidad de Tepatitlán de Morelos, Jalisco (México) y con una edad promedio de 16.74 años. Se aplicó un cuestionario de asociación libre en el que se pidió a los participantes evocar una lista de cognemas asociados a la palabra hombre para posteriormente jerarquizarlos en orden de importancia en relación con la palabra estímulo. Se realizó un análisis prototípico de importancia-frecuencia. Se encontró que los hombres representan a su propio género con representaciones favorables y positivas dadas a través de los cognemas trabajador, honesto, responsable, amable e inteligente; también se encontraron elementos que hacen referencia a la incorporación del discurso moderno de la equidad. No obstante, de igual manera fueron evidentes las representaciones que refieren a los estereotipos típicos del género masculino, reflejados a través de los cognemas trabajador, responsable, machista, caballeroso y fuerte.
Sanitization of sports mouthguards
Authors: Eli Luis Namba  , Amanda Strapasson  , Jackeline Jarzynski  , Samantha Pusgley Baratto  , Paulo Henrique Tomazinho
Published: August 2022

Mouthguards are removable intra-oral devices that, if used correctly, make the protection of the teeth and soft tissues such as gums, lips and cheeks from the impact during the sport activity. Objective: To know about the habits and attitudes towards the hygiene and use of mouthguards for athletes and evaluate the ability of a new product in spray form to decontaminate mouthguards. Material and methods: An interview by means of a questionnaire was conducted with 22 men, young adults, rugby players, in order to know their habits and attitudes about the use and cleaning of mouthguards. After this step, microbiological testing was conducted to evaluate the efficacy of a test product in the decontamination of mouthguards. Results: The sample consists of young adults, well-educated, but who had little information about cleaning of mouthguards. Only one participant executed the decontamination adequately. By microbiological assessing the test product was effective in decontaminating the samples of mouthguards. Conclusion: The risk of saliva contamination of mouthguards, the hygiene care and storage and the need for disinfection of these devices should be better disseminated among professionals and especially among athletes. The test product was effective in decontaminating salivary mouthguards.
Ludwig’s angina: diagnosis and treatment
Authors: Tiago André Fontoura de Melo  , Tiago Rücker  , Marcos Paulo Dias do Carmo  , Luis Eduardo Duarte Irala  , Alexandre Azevedo Salles
Published: August 2022

Ludwig’s angina is often an infection of odontogenic origin affecting the soft tissues of the submandibular, sublingual and submental area. Objective: This review aimed to analyze the existing literature regarding the clinical features, applications for diagnosis and treatment modalities of Ludwig’s angina. Literature review: Because it is a disease of rapid evolution, and if not previously identified, may compromise the patient’s general health and even lead to death. Conclusion: Therefore, it is important to identify the correct diagnosis based on careful and complementary clinical examination, together with an effective drug coverage and early surgical intervention to provide greater control of the patient’s health.
Apicoectomy after conventional endodontic treatment failure: case report
Authors: Lorena Oliveira Pedroche  , Neisiana Barbieri  , Flávia Sens Fagundes Tomazinho  , Luciene Miranda Ulbrich  , Denise Piotto Leonardi  , Stephanie Martins Sicuro
Published: August 2022

Paraendodontic surgery is a safe and adequate alternative when teeth are not responding to conventional treatment and endodontic re-treatment. It must only be applied in specific situations. Endodontic treatment failures can be related to: extraradicular infections such as periapical actinomycosis; to foreign body reactions that can be caused by endodontic material extrusion; to endogenous cholesterol crystal accumulation in apical tissues; and unresolved cystic lesion. Paraendodontic surgery comprehends a set of procedures recommended in periapical diseases treatment, when traditional endodontic therapy does not obtain favorable outcomes. Objective: To report a clinical case where an apicoectomy was indicated due to failure in conventional endodontic treatment. Case report and Conclusion: Clinical case report of a tooth with unsatisfying conventional endodontic treatment history, due to lack of treatment in fourth root canal and an unsuccessful apicoectomy, since the lesion and the fistula had persisted. It was chosen to retreat tooth #26 and perform a new apicoectomy in the mesiobuccal root. The treatment was successful due to absence of fistula and painful symptoms and due to periapical bone repair.
Hidden caries’ challenge diagnosis: case report
Authors: Fernanda Mara de Paiva Bertoli  , Bruno Marques da Silva  , Mariana Dalledone  , Estela Maris Losso
Published: August 2022

Hidden caries is a term used to describe occlusal dentine caries that is missed on a visual examination, but is large and demineralised enough to be detected by another exam for example, radiographs. Case report: This article reports a case of large dentine caries, which presented as to be a small pit-and-fissure carious lesion on the occlusal surface of the right mandibular permanent first molar in a 10-year-old girl. The treatment included root canal treatment and the sealing of the cavity with composite resin. Conclusion: Careful visual examination, with cleaning and drying of teeth, associated to bitewing radiographs may improve occlusal caries detection. Dentists should examine bitewing radiographs carefully for proximal caries and occlusal demineralization. Radiographs are an effective method of caries diagnosis that can avoid large destruction and allows less invasive treatment.
colorimetric photoelastic analysis of tension distribution around dental implants
Authors: João César Zielak  , Marcelo Filietaz  , Felipe Belmonte Archetti  , Paulo Roberto Camati  , Thalyta Verbicaro  , Ricardo Scotton  , Adilson Yoshio Furuse  , Carla Castiglia Gonzaga
Published: August 2022

To demonstrate a colorimetric photoelastic analysis of tension distribution around dental implants under axial loads. Material and methods: Eight different designs of implant from two manufacturers were connected to their abutments, placed into epoxy resin blocks and observed under a polariscope coupled to a universal testing machine while subjected to axial loads of 5 N. The obtained images were quantitatively analyzed by image analysis software. Results: A strong correlation was found between the surface area and the implant fringe transition area (magenta color) of most samples (r = 0.908), and a moderate correlation was found between the fringe transition area and the mean thread height of the implants (r = 0.706, or r = 0.768 using a quadratic function). Conclusion: By this biomechanical study, it was possible to demonstrate a correlation of some implant characteristics to the colored fringe areas of tension distribution, a colorimetric method that can be used in comparative studies of photoelastic analysis. Clinical significance: An accurate planning and knowledge of oral implant biomechanics is important so that a safe and long-lasting
Efficacy of gutta-percha solvents used in endodontic retreatments
Authors: Fábio de Almeida Gomes  , Ana Paula Barros Daniel  , Rodrigo Arraes Nunes  , Anna Lygia Nunes Fernandes  , Claudio Maniglia-Ferreira  , Humberto Ramah Meneses de Matos  , Taffarel Canuto Nepomuceno
Published: August 2022

The aim of this study was to evaluate the effectiveness of four different solvents and classify them according to their potential of action. Material and methods: Four solvents were tested: xylene, eucalyptol, orange oil and chloroform. Twelve gutta-percha points (medium-large), sectioned at 10 mm were used and divided into four groups, resulting in three samples for each solvent. The gutta-percha points were weighed on an analytical balance before being subjected to the action of solvents and subsequently put onto watch glasses that were immersed into the solutions for the following times: 1, 2, 3, 4 and 5 minutes. The percentage of mass loss was registered through weighing after every minute of action of the solvent on the points. Results: All solvents showed the first minute of action as the period of greatest power of dissolution because they act only on the gutta-percha itself and not on the other components of the point, suggesting that at the remaining minutes there would be a lower percentage of dissolution because there was a smaller amount of gutta-percha within the points. Conclusion:Chloroform and xylene showed similar results regarding the rate of dissolution of gutta-percha, yet they were statistically significant higher than eucalyptol and orange oil from 1 to 5 minutes.
Image adjustments on digital panoramic radiographs using Adobe Photoshop CS3 software
Authors: Sérgio Soares Batista  , Francine Kühl Panzarella  , Orivaldo Tavano  , Agenor Montebelo Filho  , José Luiz Cintra Junqueira
Published: August 2022

: Favourable manipulation of images may be the greatest advantage of the digital radiographic compared to the conventional film. The current development of the cost-benefit of intra- and extraoral digital technology, besides the increase of computerized practices has turned the digital image into a superior alternative to conventional radiographs, in several aspects. Objective: To demonstrate image adjustments on digital panoramic radiographs using Adobe Photoshop CS3 (Creative Suite 3) software in order to enhance digital images. Case reports: Digital treatment was conducted in two different cases using two filters available in Adobe Photoshop CS3: Smart Sharpen and Unsharp-Mask. Both filters improve overall image quality. In the second case, after brightness and contrast adjustments, it was possible to have a detailed visualization of radiopaque and radiolucent areas. Conclusion: The application of brightness and contrast adjustments and filters are feasible methods in order to achieve diagnostic precision.
Repair on silorane-based composite
Authors: Dilcele Silva Moreira Dziedzic  , Shiffa al Sayd  , Leonardo Fernandes da Cunha  , Lino Oliveira Carvalho de Santana  , Carla Castiglia Gonzaga  , Adilson Yoshio Furuse
Published: August 2022

Silorane-based composites have low polymerization shrinkage and good color stability. However, the effectiveness and the best surface treatment to carry out repairs to this type of restoration is unclear. Objective: To evaluate the effect of different types of repair made on a silorane-based composite. Material and methods: 80 disks of silorane-based composite were prepared (Filtek P90, 3M ESPE) and divided into eight groups (n = 10), according to the surface treatment being carried out before repairs of either the same silorane composite or a dimethacrylate material (Filtek Z350, 3M ESPE) were conducted. In two groups the immediate adhesion without repair (positive control) was evaluated. In other two groups repairs without any surface treatment (negative control) were evaluated. Surface treatments before the repair of the four remaining groups included the application of adhesive systems specific to silorane (Silorane System Adhesive, 3M ESPE) or to dimethacrylate (Adper Single Bond 2, 3M ESPE) and roughening followed by application of adhesive system. All groups were stored into distilled water at 37°C for 1 week prior to the microshear bond strength evaluation. Results: The group immediate adhesion silorane-dimethacrylate and group repair silorane-dimethacrylate without surface treatment showed lower microshear bond strength values and were statistically different from groups with surface treatment and immediate adhesion silorane-silorane (p < 0.05). Conclusion: Surface treatments with application of adhesive systems compatible with the repair material or roughening prior to the application of these adhesive systems are suitable for repairing silorane-based composites.
Analysis of salivary pH, flow rate, buffering capacity, concentrations of calcium, urea and total proteins in 2-8 years-old children with Down’s syndrome
Authors: Gizele Franco  , Rafaella Saab  , Luciani Variani Pizzatto  , Maria Fernanda Torres  , Andréa Paula Fregoneze  , João Armando Brancher
Published: August 2022

Down syndrome (DS) is a genetic disorder caused by trisomy of chromosome 21. It is the most common chromosomal abnormality found in humans. Despite the motor difficulties and biofilm accumulation, individuals with DS have low caries prevalence. In this context it is assumed that saliva plays an important role in maintaining oral health. Objective: To evaluate the following salivary components: pH, buffering capacity and salivary flow volume in children with DS aging 2-8 years-old in the city of Curitiba (PR). Material and methods: Saliva samples were collected from 20 children with DS. The following parameters were evaluated: buffering capacity, flow rate, pH, and concentrations of calcium, urea and total proteins. Results:There was a normal distribution among the variables and the values observed were not statistically significant (p > 0.05). Conclusion:The results of this study revealed that there were no statistically significant differences in salivary flow, pH, buffering capacity, urea, calcium and total proteins in the subjects studied.
Unusual transmigration of canines – report of two cases in a family
Authors: Sulabha A. Narsapur  , Sameer Choudhari  , Shrishal Totad
Published: August 2022

Transmigration is pre-eruptive migration of tooth across the midline. The etiology of this rare anomaly is unknown. Transmigration is largely related to mandibular canines. Although maxillary canine transmigrations are found in the literature, they are still a rare entity. Objective: The aim of the present paper is to report two cases of unusual transmigrations of canines in two immediate members of a family and to report the first case of simultaneous transmigration of maxillary and mandibular canines in an Indian adolescent. Case report: A rare case of simultaneous transmigration of maxillary and mandibular canine in Indian adolescent along with bilateral transmigration of mandibular canines in her father is described here. Conclusion: Transmigration of canines in two immediate members of family needs to be further studied for familial occurrence of transmigration.
Maxillary squamous cell carcinoma: diagnosis and evolution of an inoperable case
Authors: Luana Beber Yoshizumi  , Mariah Scotti Alérico  , José Miguel Amenábar Céspedes  , Cleto Mariosvaldo Piazzetta  , Cassius Carvalho Torres-Pereira
Published: August 2022

Squamous cell carcinoma (SCC) is a malignant neoplasia, originating from the oral lining epithelium, responsible for approximately 90-95% of malignancies in this location. Incidence and mortality rates for oral SCC may vary due to personal habits, socioeconomic characteristics, environmental factors and quality of health care. This study reports the aggressive evolution of SCC with a delayed diagnosis and the impossibility of immediate curative therapy. Case report: A 47-year-old brown male patient, smoker and drinker was referred by a primary health care center to the Stomatology Clinic at UFPR (Federal University of Paraná). The diagnosis of well-differentiated SCC was confirmed by histopathological examination. The patient was referred to a specialized service where an oncology team defined the case as inoperable due to lung function limitations and advanced tumor staging. The patient underwent lung physiotherapy sessions until reaching clinical conditions to undergo oncologic therapy which included radiotherapy and chemotherapy. Conclusion: The reported case highlights the importance of establishing an early diagnosis for SCC. There is a need of facilitating and speeding the access to both health care services and information that lead patients to seek professional assistance as soon as the first disease signs appear.
A 7-year retrospective study of biopsied oral lesions in 460 Iranian patients
Authors: Shila Ghasemi Moridani  , Fatemeh Shaahsavari  , Mohammad Bagher Adeli
Published: August 2022

Frequency of oral lesions is varied in different population and knowledge of diseases prevalence in a geographic location will improve preventive measures. Objective: The objective of this study was to determine the prevalence of oral biopsied lesions in a major oral pathology laboratory center of city of Tehran. Material and methods: A retrospective study was done on data obtained from the archive of oral and maxillofacial pathology department of Islamic Azad University, dental branch of Tehran, from 2005 to 2011. Following variables were analyzed: age, gender, anatomic location, and the histological results obtained. Lesions were classified to 18 different categories. Data were analyzed using the SPSS version 12.0 for windows Xp. All the data were recorded in Microsoft Office Excel for further evaluation and making a data bank to easy access.Results: Of the 460 patients studied, the mean age was 38 years. The most frequent lesions were in the group of reactive lesions (22.51%), followed by odontogenic cysts. The most frequent lesion was radicular cyst and odontogenic keratocyst (keratocystic odontogenic tumor). Malignant lesions constituted 2.38%, of which squamous cell carcinoma was the most common malignancy (1.52%). Mandible was the most common location for occurrence of lesions (32.6%) followed by gingiva (11.95%). Conclusion: Our study provides helpful information of oral lesion’s distribution in an Iranian population. The results showed high frequency of odontogenic keratocyst (keratocystic odontogenic tumor) which is not in agreement with other studies and need more evaluation of etiological factors.
Hypochlorite-induced severe cellulitis during endodontic treatment: case report
Authors: Bernardo Almeida Aguiar  , Fábio Almeida Gomes  , Cláudio Maniglia Ferreira  , Bruno Carvalho de Sousa  , Fábio Wildson Gurgel Costa
Published: August 2022

Sodium hypochlorite is a solution used in endodontic treatment, and if an accidental apical extrusion occurs, serious complications may affect soft tissue. Objective: The aim of this article is to present a case of apical extrusion of sodium hypochlorite (NaOCl) during root canal system instrumentation. Case report:A 28-year-old woman sought a local dental service for root canal treatment of tooth #24. Conventional endodontic treatment was adopted, which consisted of the use of 2.5% NaOCl solution as irrigation solution applied with a 10-ml syringe and 22G hypodermic needle. At that time, the patient reported extreme pain and a burning sensation in the left maxillary region, followed by the formation of intense edema. A clinical diagnosis of hypochlorite-induced cellulitis was made. The patient was treated immediately with amoxicillin (500 mg, orally) at intervals of 8 h for 7 days and dexamethasone (4 mg, intramuscularly) at intervals of 24 h for 3 days. In the subsequent endodontic treatment, 2% chlorhexidine gel applied with a 5-ml syringe and 24G needle was used as irrigation for a better control of treatment and to prevent new accidents. The root canals were instrumented using adequate crown-down technique, which provides a conical shape, and filled by lateral condensation technique. The patient was symptom free at the 8-month clinical follow-up. Conclusion: Dentists should always carefully follow all stages of dental treatment planning without neglecting any of them, paying attention to the solutions used and their storage as well as performing a specific technique with maximum accuracy. If an accident occurs, the appropriate handling of the situation will enable the satisfactory completion of treatment.
Analysis of active chlorine releasing and pH of sodium hypochlorite solutions used in Endodontics
Authors: Cristhiany Martins Lopes Machado  , Antônio Henrique Braitt  , Gladyvam Rabêlo Braitt  , Evaldo Almeida Rodrigues  , Carlos Eduardo da Silveira Bueno
Published: August 2022

The use of a suitable irrigation solution and a correct root system shape effectively contributes to the success of endodontic treatment. Among the irrigating solutions used in Endodontics, sodium hypochlorite has been the most used because of many qualities. However, this substance must have chemical stability of its properties, by maintaining the potential of hydrogen (pH) and chlorine concentrations appropriately. Objective: The aim of this study was to evaluate active chlorine releasing and pH of some sodium hypochlorite solutions used in endodontic clinical practice. Material and methods: The solutions tested in this study were 0.5% Dakin, 1% Milton, 2% Chlorinated Soda, and household bleaches (Brilux®and Qboa®), which were opened at the same period and first used, with the same storage modus but with different manufacturing dates. The pH was measured with a digital device, and the active chlorine content was obtained through iodometric titration. Results:All solutions presented chlorine content not smaller than that informed in the flasks, ranging from 1% to 2.4%; pH was higher in all solutions, between 9 and 13. Conclusion: Based on the method applied and the results obtained, it was possible to conclude that sodium hypochlorite solutions used specifically in Dentistry (Dakin and Milton solutions and Chlorinated Soda), showed on the labels the hypochlorite content. On the other hand, household bleaches (Brilux® and Qboa®) showed the chlorine content. It was not possible to compare pH authenticity, due to lack of description on the label.
Myiasis in maxillofacial region: series of three cases
Authors: Cleverson Patussi  , Daniela Cristina Lunelli  , Regiane Benez Bixofis  , Maria Isabela Guebur  , José Luiz Dissenha  , Laurindo Moacir Sassi
Published: August 2022

Myiasis is a disease caused by larvae of flies in organs and tissues of man or other vertebrate animals, where they install and evolve as parasites. The human myiasis is common in tropical countries, most frequently affecting rural people, immunocompromised patients and those with psychiatric disorders. It has great destructive potential and needs adequate prevention and treatment for resolution or non-occurrence of this manifestation. Objective: This paper aims to report a series of three cases of patients with presence of myiasis in face: 1) firearm injury postoperative complication in the mandible in a drug user patient; 2) wound after trauma in the region of the upper lip in a patient using illicit drugs; and 3) complication due to poor oral hygiene of a patient with neurological and motor deficits. Case report: The care required by these patients is different because this complication is easily prevented by basic and personal health care, although it represents a complicating factor for surgical procedures and/or dental care. Conclusion: The role of health professionals in patients with special needs and/or drug addiction become sometimes a challenge for dental practice, requiring individualized attention to each patient.
Bond strength of dentin submitted to bleaching and restored with different materials
Authors: Nelize Marcelino Pessarello  , Yara T. Correa Silva-Sousa  , Fuad Jacob Abi Rached-Junior  , Aline Evangelista Souza-Gabriel
Published: August 2022

The use of adhesive composite resin with fluoride and with greater fluidity can be favorable to the restoration of the palatal/lingual face of teeth submitted to internal bleaching. Objective:This study evaluated the bond strength of adhesive systems and composite resins to bleached dentin. Material and methods: Forty maxillary canines were sectioned to obtain 40 blocks (5 x 5 mm) of intracoronary dentin. The fragments were included and bleached with 37% carbamide peroxide. After 7 days, the specimens were divided into two groups according to the adhesive system: with (Optibond Solo Plus) and without (Single Bond) fluoride and subdivided into 2 subgroups (n = 10) according to the composite resin: microhybrid (Z250) and flowable (Z350). The restoration was carried out through a bipartite matrix. After 24 hours, the specimens were subjected to shear bond strength test. The data (MPa) were analyzed by ANOVA and Tukey test (α = 0.05). Results: The best results (p < 0.05) were obtained for fluoridated adhesive (7.44 ± 2.35) compared with that without fluoride (5.36 ± 2.01); flowable resin (7.76 ± 2.23) performed better than microhybrid resin (5.03 ± 1.72). When the two variables were associated, the highest results were obtained for the specimens restored with fluoridated adhesive and flowable resin(9.04 ± 1.92). Lower results were observed for non-fluoridated adhesive + microhybrid resin – control (4.24 ± 1.59), without statistically significant differences when compared with the fluoridated adhesive + microhybrid resin (5.83 ± 1.52). Conclusion: The combination with fluoridated adhesive and flowable resin increases the shear bond strength of bleached dentin.
Analysis of the instrumentation time and cleaning between manual and rotary techniques in deciduous molars
Authors: Sérgio Luiz Pinheiro  , Leniana Santos Neves  , José Carlos Pettorossi Imparato  , Danilo Antônio Duarte  , Carlos Eduardo da Silveira Bueno  , Rodrigo Sanches Cunha
Published: August 2022

The rotary instrumentation provides shorter instrumentation time with greater comfort for the patient but few studies have been conducted on primary teeth. Objective: this study compared the cleaning ability and instrumentation time between manual and rotary techniques in deciduous molars. Material and methods: a total of 15 molars were selected, submitted to coronal opening and root canal filled with India ink. After 48 hours, the teeth were divided into three groups: G1 – manual instrumentation with K files, G2 – rotary system Endowave, and G3 – rotary system ProTaper. After instrumentation, the teeth were sectioned and three blinded examiners evaluated the root canal cleaning. The mode of scores of examiners was analyzed by the Kruskal-Wallis test. The instrumentation time was recorded and the results were statistically analyzed by ANOVA. Results: the ProTaper system presented shorter instrumentation time compared to manual instrumentation (p = 0.0339). Endowave system did not present statistically significant difference in the instrumentation time compared to the other groups. There were no significant differences between groups concerning the ability of root canal cleaning (p = 0.6188). Conclusion: ProTaper system revealed shorter treatment time and similar cleaning ability compared to the other techniques, thus being indicated for deciduous teeth.
Morphologic assessment of dental surface/ glass ionomer cement interface: influence of Er:YAG laser pretreatment
Authors: Aline Evangelista Souza-Gabriel  , Daniela Thomazatti Chimello-Sousa  , Regina Guenka Palma-Dibb  , Jesus Djalma Pécora  , Silmara Aparecida Milori Corona
Published: August 2022

The aim of this study was to assess the surface and the substrate/glass ionomer cement (GIC) interface after Er:YAG laser irradiation by means of scanning electron microcopy. Material and methods: Thirty human third molars were selected and had their roots removed. Crowns were sectioned to obtain discs that were randomly assigned to three groups according to the surface pretreatment: 40% polyacrylic acid (control); Er:YAG laser irradiation (80mJ/2Hz) or Er:YAG laser followed by 40% polyacrylic acid. Two discs of each group were put aside to the surface analysis and the others were bisected. One half received Ketac-Fil and the other received Fuji II LC. Specimens were prepared for SEM and were analyzed under different magnifications. Results: Er:YAG laser group showed no adhesive interface for both enamel and dentin, but strongly damaged the interface build-up for dentin/Fuji II LC. The application of laser irradiation followed by the polyacrylic acid exhibited gaps and irregularities for both substrates. Conclusion:Er:YAG laser irradiation combined or not with 40% polyacrylic acid produced a surface unfavorable for GIC interaction, especially for the resin-modified ones.
Papillary regeneration: anatomical aspects and treatment approaches
Authors: Jaína Dias de Oliveira  , Carmen Mueller Storrer  , Andrea Maria Sousa  , Tertuliano Ricardo Lopes  , Juliana de Sousa Vieira  , Tatiana Miranda Deliberador
Published: August 2022

This paper aims to report a literature review on the anatomy and morphology of the interproximal papilla and present the options of both surgical and nonsurgical treatment for the recovery of interdental papilla. Literature review: The loss of the interdental papilla because of the interproximal bone loss accounts for aesthetic, phonetic and functional problems of patients with periodontal disease. The interproximal tissue reconstruction has been reported in literature through both surgical procedures with the use of subepithelial connective tissue graft, restorative and orthodontic treatment. Conclusion: The etiology of gingival black space is multifactorial, therefore, it is important to diagnose properly the etiological factor to establish an appropriate treatment planing. However, the treatment approaches are not predictable and further studies are necessary to recommend the clinical practices available to date.
Anatomical variations in the permanent mandibular canine: forensic importance
Authors: Rhonan Ferreira da Silva  , Mauro Machado do Prado  , Tessa de Lucena Botelho  , Rogério Vieira Reges  , Décio Ernesto de Azevedo Marinho
Published: August 2022

The uniqueness of dental morphology plays an important role in Forensic Odontology, especially for human identifications, in which a single tooth can provide information for dental identification. Objective: To address the importance of a permanent lower canine with two roots for dental identification considering the internal and external morphology of the canine roots. Case report: To report a forensic case in which a two-rooted permanent lower canine was found in a decomposed human body. Conclusion: Although the victim was not identified by the dental parameter, it was observed that this type of morphological variation is of little incidence in some populations, therefore constituting a valuable tool for dental human identifications.
Heat-Shock Triggers Inverted Induction of Hypo-S-Nitrosylation and
Hyper-O-GlcNAcylation
Authors: Kim Min-Jae , Ryu In-Hyun , Do Su-Il
Published: August 2022

Introduction:

Protein S-nitrosylation (SNO) and O-GlcNAcylation are important
posttranslational modifications. The biological connection between SNO and O-GlcNAcylation is
not clear.

Objective:

We aim to identify the crosstalk between SNO and O-GlcNAcylation during heat-shock.

Methods:

Ex vivo heat-shock on mouse tissues together with in vitro heat-shock on culture cells was
performed and global levels of SNO and O-GlcNAcylation were analyzed with Biotin-switch assay
(BSA) and RL2 immunoblots.

Results:

Heat-shock induces hypo-SNO in parallel with hyper-O-GlcNAcylation. Inverted induction
of hypo-SNO and hyper-O-GlcNAcylation is globally progressed in a time-dependent manner.

Discussion:

Moreover, heat-shock ubiquitously facilitates S-denitrosylation (SdeNO) of
endogenous SNO-proteins including SNO-OGT, SNO-Hsp70, SNO-Hsp90, SNO-Akt, and SNOactin.
Particularly, SdeNO of SNO-OGT leads to enhanced OGT activity.

Conclusion:

These findings provide mechanistic evidence that heat-shock triggers SdeNO of SNOOGT
by which OGT activity is up-regulated, resulting in hyper-O-GlcNAcylation.
Serine Racemase Expression Differentiates Aging from Alzheimer’s Brain
Authors: Wu Shengzhou , Zhou Jing , Zhang He , Barger Steven W.
Published: August 2022

Aging is an inevitable process characterized with progressive loss of physiological integrity and increased susceptibility to cancer, diabetes, cardiovascular, and neurodegenerative diseases; regarding the last, aging is the primary risk factor for Alzheimer’s disease (AD), the most common cause of dementia. AD is characterized by brain pathology including extracellular deposition of amyloid aggregation and intracellular accumulation of neurofibrillary tangles composed of hyperphosphorylated tau protein. In addition, losses of synapses and a wide range of neurons are pivotal pathologies in AD brain. Accumulating evidence demonstrates hypoactivation of hippocampal neural networks in the aging brain, whereas AD-related mild cognitive impairment (AD-MCI) is begins with hyperactivation, followed by diminution of hippocampal activity as AD develops. The biphasic trends of the activity of hippocampal neural network are consistent with the alteration of N-methyl-D-aspartate receptor (NMDA-R) activity from aging to prodromal (AD-MCI) to mid-/late stage AD. D-Serine, a product of racemization catalyzed by serine racemase (SR), is an important co-agonist of the NMDA-R which is involved in synaptic events including neurotransmission, synaptogenesis, long-term potentiation (LTP), development, and excitotoxicity. SR and D-serine are decreased in the hippocampus of the aging brain, correlating with impairment of cognitive function. By contrast, SR is increased in AD brain, which is associated with a greater degree of cognitive dysfunction. Emerging studies suggest that D-serine levels in the brain or in cerebral spinal fluid from AD patients are higher than in age-matched controls, but the results are inconsistent. Very recently, serum D-serine levels in AD were reported to correlate with sex and clinical dementia rating (CDR) stage. This review will discuss alterations of NMDA-R and SR in aging and brain, and the mechanisms underlying the differential regulation of SR will be probed. Collectively, we propose that SR may be a molecular switch that distinguishes the effects of aging from those of AD on the brain.
Human microRNA-4433 (hsa-miR-4443) Targets 18 Genes to be a Risk
Factor of Neurodegenerative Diseases
Authors: Ge Xing , Yao Tingting , Zhang Chaoran , Wang Qingqing , Wang Xuxu , Xu Li-Chun
Published: August 2022

Background:

Neurodegenerative diseases, such as Alzheimer's disease patients (AD), Huntington's disease (HD) and Parkinson’s disease (PD), are common causes of morbidity, mortality, and cognitive impairment in older adults.

Objective:

We aimed to understand the transcriptome characteristics of the cortex of neurodegenerative diseases and to provide an insight into the target genes of differently expressed microRNAs in the occurrence and development of neurodegenerative diseases.

Methods:

The Limma package of R software was used to analyze GSE33000, GSE157239, GSE64977 and GSE72962 datasets to identify the differentially expressed genes (DEGs) and microRNAs in the cortex of neurodegenerative diseases. Bioinformatics methods, such as GO enrichment analysis, KEGG enrichment analysis and gene interaction network analysis, were used to explore the biological functions of DEGs. Weighted gene co-expression network analysis (WGCNA) was used to cluster DEGs into modules. RNA22, miRDB, miRNet 2.0 and TargetScan7 databases were performed to predict the target genes of microRNAs.

Results:

Among 310 Alzheimer's disease (AD) patients, 157 Huntington's disease (HD) patients and 157 non-demented control (Con) individuals, 214 co-DEGs were identified. Those co-DEGs were filtered into 2 different interaction network complexes, representing immune-related genes and synapse-related genes. The WGCNA results identified five modules: yellow, blue, green, turquoise, and brown. Most of the co-DEGs were clustered into the turquoise module and blue module, which respectively regulated synapse-related function and immune-related function. In addition, human microRNA-4433 (hsa-miR-4443), which targets 18 co-DEGs, was the only 1 co-up-regulated microRNA identified in the cortex of neurodegenerative diseases.

Conclusion:

214 DEGs and 5 modules regulate the immune-related and synapse-related function of the cortex in neurodegenerative diseases. Hsa-miR-4443 targets 18 co-DEGs and may be a potential molecular mechanism in neurodegenerative diseases' occurrence and development.
Influence of Tooth Surface Wear and Nonlinear Contact Stiffness on
Dynamic Responses of Helical Gears
Authors: Han Lin , Li Weiguang , Qi Yang , Liu Shaoshuai
Published: August 2022

Background:

Tooth surface wear is inevitable in helical geared transmission. Consequently,
the worn profile deviates from the ideal involute one. As a result, the structural stiffness of worn tooth
and contact stiffness of tooth-pair are both changed.

Methods:

This work presents an improved calculation method for structural stiffness of worn teeth by
combining slicing and potential energy method, considering non-uniform distribution of wear amount
along the tooth surface. Then, a nonlinear contact stiffness model is employed to investigate the influence of wear on contact stiffness. Meanwhile, taking wear as one kind of profile deviation, the analytical model of time-varying mesh stiffness (TVMS) of helical gear pair is derived. Furthermore, governing equations with 6 degree-of-freedom are established and influences of wear on dynamic responses
are revealed.

Results:

Results indicate that structural stiffness of worn teeth decreases but contact stiffness does not
always keep increasing or decreasing. The fluctuation of dynamic transmission error with the nonlinear
contact model is not as significant as that from the constant contact stiffness model.

Conclusion:

The approach presented in this work is suitable for condition monitoring of helical gears in
view of long-term service
Desarrollo de un concentrador centrífugo neumático para el procesamiento en seco de partículas ultrafinas de minerales auríferos: diseño del prototipo
Authors: Mamani-Quispe Jhon Marcelo , Calisaya-Mamani Federico Eleodoro , Taco-Cervantes Homar Henrry , Ascuña-Rivera Víctor Benigno , Juárez-Pinto Diego Edgardo , Guzmán-Jacobo Yvan César , Mamani-Añamuro Mireya Mariela
Published: August 2022

El objetivo del presente trabajo es el diseño de un prototipo de concentrador centrifugo neumático que permita a la minería de pequeña escala que se desarrolla en lugares desérticos y aislados, procesar in situ, de manera limpia, sin uso de agua y reactivos químicos, minerales auríferos ultrafinos. Se aplicó un modelo matemático basado en el análisis físico-fenomenológico del mecanismo de separación de sedimentación diferencial en una película de fluido de flujo laminar, para determinar la trayectoria de las partículas en el interior del tazón del concentrador centrifugo en función de las variables de geometría del tazón, variables de operación y características físicas de la partícula y fluido. Las simulaciones realizadas mostraron un efecto notable del uso de aire en vez de agua sobre la trayectoria de las partículas dentro de la película de fluido. Los resultados también mostraron que la capacidad del concentrador para la separación de partículas por diferencia de densidades más que por diferencia de tamaños, se favoreció al aplicar bajas velocidades de rotación, altos caudales de alimentación de aire y para tamaños de partícula en el rango ultrafino (< 40 μm). El prototipo construido permitirá realizar pruebas experimentales a nivel de laboratorio que complementen la compresión del proceso y afinar el diseño del concentrador.
Predicción de la generación de residuos sólidos domiciliarios con machine learning en una zona rural de Puno
Authors: Cerna Cueva Alberto Franco , Rosas Echevarría Cesar Wilfredo , Perales Flores Roberto Sixto , Ataucusi Flores Pierina Lisbeth
Published: August 2022

La gestión de residuos sólidos es uno de los principales desafíos ambientales en todas las ciudades del mundo debido a factores como el crecimiento poblacional y los hábitos de consumo. Una de las principales herramientas para el diseño de proyectos de gestión de residuos, es la estimación de la generación per cápita, sin embargo, el método tradicional para obtener esta información demanda mucho esfuerzo y tiempo, por ello esta investigación plantea un enfoque alternativo de la estimación de la generación per cápita a partir de factores socioeconómicos. Para ello se recogió información socio económica demográfica e información sobre la generación per cápita de residuos sólidos de 50 familias, posteriormente se determinaron las variables que tienen influencia significativa a partir del coeficiente de correlación ρ de Spearman para las variables numéricas y un ANOVA para las variables categóricas con un umbral de aceptación de 0.4 y 0.05 respectivamente. Las variables seleccionadas se utilizaron para entrenar los modelos de redes neuronales, regresión lineal múltiple, support vector machine, procesos gaussianos y random forest, cuyos desempeños fueron de R2 = 0.986, 0.982, 0.959, 0.837, 0.832; respectivamente. Para la validación se utilizó validación cruzada y partición de datos. Los resultados indican que las variables influyentes son el ingreso per cápita, el gasto en insumos y productos, el tamaño familiar y los servicios del hogar. Se concluye que las predicciones de los modelos son confiables (RMSE desde 8g a 27g) y a partir de ellas se pueden diseñar proyectos.
Completeness of Medical Record Documents: Exploration on Causes and Solutions
Authors: Syukria Orin Annahriyah , Wardhani Viera
Published: August 2022

The delay in returning inpatients' medical record documents (MRDs) to the medical records subdivision can cause some effects. This study was conducted to explore MRD completeness and the factors causing the delays in returning the document. This study used a descriptive observational method. Exploration was carried out on 21 MRDs using a checklist as an instrument. Besides, data were obtained through interviews involving the heads of related subdivisions and surveys on 52 nurses. Data were collected using an interview guide and a nursing work index-revised (NWI-R) instrument adapted into Indonesian. MRDs returned on time were complete in content and form than documents returned late to the medical records subdivision. One of the root causes of this problem is the officer factor, in this case is the nurse. The result of the NWI-R assessment is 3.15 (a maximum score of 4), meaning that the work environment in X Hospital supports nurses in carrying out their duties well. The highest score, 3.31, is the nurse-doctor relationship factor. The lowest value, 2.93, is the factor of resources adequacy to provide quality services. The possible solutions are to carry out routine briefings related to filling in and returning DRM followed by training.
Factors Contributing to Length of Stay Prolongation among Emergency Room Patients during the Covid-19 Pandemic: A Study at Persada Hospital
Authors: Simanungkalit Sylvia Kitty , Holipah Holipah , Dewanto Aryo , David David
Published: August 2022

Extended length of stay (LOS) in the Emergency Department (ED) results in crowding, potentially causing adverse events and patient dissatisfaction. The Covid-19 pandemic has forced hospitals to implement screening procedures that can extend the LOS of patients in the ED. This study aimed to provide an overview of changes in ED LOS during the pandemic and its contributing factors. This study used a descriptive approach through observation and interviews. LOS observations were conducted using the time & motion study method to determine the average time in each ED stage. The observation results identified the differences in the average LOS during the Covid-19 pandemic, which was 2 hours 39 minutes 52 seconds, and the longest time was on laboratory examination (2 hours 59 minutes 27 seconds). A lengthy laboratory examination duration is due to the additional laboratory examination procedure (serology) for SARS COV-2, suboptimal screening team, and the absence of notification in the hospital information system.