bluuebunny/crossref_metadata_2025 huggingface dataset:
Cultural Bereavement and Resilience in Refugee Resettlement: A Photovoice Study With Yazidi Women in the Midwest United States
Authors: Tippens Julie A. , Roselius Kaitlin , Padasas Irene , Khalaf Gulie , Kohel Kara , Mollard Elizabeth , Sheikh Izdihar (Vianne)
Published: April 2021

This study explored how ethnic Yazidi refugee women overcome adversity to promote psychosocial health and well-being within the context of U.S. resettlement. Nine Yazidi women participated in two small photovoice groups, each group lasting eight sessions (16 sessions total). Women discussed premigration and resettlement challenges, cultural strengths and resources, and strategies to overcome adversity. Yazidi women identified trauma and perceived loss of culture as primary stressors. Participants’ resilience processes included using naan (as sustenance and symbol) to survive and thrive as well as by preserving an ethnoreligious identity. Findings suggest that women’s health priorities and resilience-promoting strategies center on fostering a collective cultural, religious, and ethnic identity postmigration. Importantly, women used naan (bread) as a metaphor to index cultural values, experiences of distress, and coping strategies. We discuss implications for this in promoting refugees’ mental and psychosocial health in U.S. resettlement.
Three-Dimensional Dynamic Analysis of the Reproducibility of Verbal and Nonverbal Facial Expressions
Authors: Qiu Tiancheng , Xue Zulin , Wu Ling , Yang Rong , Liu Xiaojing , Wang Xing , Li Zili
Published: April 2021

Objective:

The aim of this study is to compare the short- and long-term reproducibility of verbal and nonverbal facial expressions of normal people using dynamic 3-dimensional (3-D) imaging.

Design:

Prospective, cross-sectional, controlled study.

Setting:

Peking University School and Hospital of Stomatology, Beijing, China.

Patients and Participants:

Twenty-seven participants, 12 males and 15 females, were recruited for this study.

Methods:

A 3-D dynamic system was applied to capture the process of 4 nonverbal facial expressions (smile lips closed, smile lips open, lip purse, cheek puff) and 2 verbal facial expressions (/i:/, /u:/) at an initial time point, 15 minutes later, and 1 week later. Key frames were selected from each expression recording sequence.

Main Outcome Measures:

The root mean square (RMS) between each key frame and its corresponding frame at rest was calculated. ΔRMS reflected the difference of the same key frames between the different sessions of the same expression of the same participant. The reproducibility of different facial expressions at different time intervals were analyzed.

Results:

There was no significant difference in verbal and nonverbal expression repeatability during a 15-minute interval, except for cheek puff motion. Following a 1-week interval, verbal expression repeatability was superior to that of nonverbal expressions ( P < .01). Compared with nonverbal expressions, the repeatability of verbal expressions did not obviously decrease with the increase in recording interval.

Conclusions:

Dynamic 3-D imaging is a useful technique for facial expression analysis. Verbal expressions showed greater reproducibility than nonverbal expressions.
Long-Term Effects of Nasoalveolar Molding in Patients With Unilateral Cleft Lip and Palate: A Systematic Review and Meta-Analysis
Authors: Padovano William M. , Skolnick Gary B. , Naidoo Sybill D. , Snyder-Warwick Alison K. , Patel Kamlesh B.
Published: April 2021

Objective:

The aim of this systematic review and meta-analysis was to investigate long-term treatment effects of nasoalveolar molding (NAM) in patients with unilateral cleft lip and palate (UCLP).

Design:

Included manuscripts met the following criteria: (1) involved patients with UCLP who received NAM; (2) included comparison group(s) who either received non-NAM passive presurgical infant orthopedic appliances (PSIO) or who did not receive any PSIO; (3) reported at least one objective or validated measure of nasolabial, craniofacial, or palatal form; and (4) had patient follow-up beyond 4 years of age.

Results:

A total of 12 studies were included in this review. Meta-analyses were possible for Asher-McDade parameters and cephalometric measurements. Compared to patients who did not receive any PSIO, those who underwent NAM therapy were more likely to have good to excellent frontal nasal form (Risk ratio: 2.4, 95% CI: 1.24-3.68) and vermillion border (Risk ratio: 1.8, 95% CI: 1.19-2.71). However, there were no statistically significant differences in cephalometric measurements between these groups. Additionally, there were no statistically significant differences between patients receiving NAM versus non-NAM PSIO. There was insufficient evidence to determine the impact of NAM on dental arch development.

Conclusions:

The preponderance of evidence in this review suggests that NAM produces benefits in nasolabial aesthetic form when compared with no appliance-based presurgical treatment. However, there is insufficient evidence to conclude whether NAM produces such benefits when compared with other passive PSIOs.
Sounds of Silence: The Reflexivity, Self-decentralization, and Transformation Dimensions of Silence at Work
Authors: Vu Mai Chi , Fan Ziyun
Published: April 2021

This article explores silence as a phenomenon and practice in the workplace through a Buddhist-enacted lens where silence is intentionally encouraged. It brings forward a reconsideration of the roles of silence in organizations by proposing emancipatory dimensions of silence—reflexivity, self-decentralization, and transformation. Based on 54 interviews with employees and managers in a Vietnamese telecommunications organization, we discuss the dynamic nature of silence, and the possible coexistence of the constructive and the oppressive aspects of silence in a workplace spirituality context. Instead of studying silence as one-dimensional, we call for an integrated view and argue that studying silence requires consideration of the multiplicity of its interconnected dimensions. By considering silence as a relational and emerging processes constructed around its vagueness and uncertainties, our study reveals the many possible ways silence is organized and organizes and sheds light on silence as a marker of the complexities and paradoxes of organizational life.
Approach to Sedation and Analgesia in COVID-19 Patients on Venovenous Extracorporeal Membrane Oxygenation
Authors: Dreucean Diane , Harris Jesse E. , Voore Prakruthi , Donahue Kevin R.
Published: April 2021

Objective:

To describe clinically pertinent challenges of managing sedation in COVID-19 patients on venovenous extracorporeal membrane oxygenation (VV-ECMO) and describe considerations for enhanced safety and efficacy of pharmacological agents used.

Data Sources:

A PubMed search was performed using the following search terms: ECMO, ARDS, sedation, COVID-19, coronavirus, opioids, analgesia, fentanyl, hydromorphone, morphine, oxycodone, methadone, ketamine, propofol, dexmedetomidine, clonidine, benzodiazepines, midazolam, lorazepam, and diazepam.

Study Selection and Data Extraction:

Relevant clinical and pharmacokinetic studies were considered. All studies included were published between January 1988 and March 2021.

Data Synthesis:

Patients with acute respiratory distress syndrome secondary to COVID-19 may progress to requiring VV-ECMO support. Agents frequently used for sedation and analgesia in these patients have been shown to have significant adsorption to ECMO circuitry, leading to possible diminished clinical efficacy. Use of hydromorphone-based analgesia has been associated with improved clinical outcomes in patients on VV-ECMO. However, safety and efficacy regarding use of other agents in this patient population remains an area of further research.

Relevance to Patient Care and Clinical Practice:

This review addresses clinical challenges associated with sedation management in COVID-19 patients requiring VV-ECMO support and provides potential strategies to overcome these challenges.

Conclusions:

Historically, sedation and analgesia management in patients requiring ECMO support have posed a challenge for bedside clinicians given the unique physiological and pharmacokinetic changes in this patient population. A multimodal strategy to managing analgesia and sedation should be used, and the use of enteral agents may play a role in reducing parenteral agent requirements.
Exploring the Synergy Between Human Systems Integration and Human Readiness Levels: A Retrospective Analysis
Authors: Savage-Knepshield Pamela A. , Hernandez Charles L. , Sines Scott O.
Published: April 2021

Using a case study approach, this article explores the benefits of leveraging human readiness levels (HRLs) in conjunction with Human Systems Integration (HSI). The U.S. Army’s HSI program emphasizes front-end planning and emphasizes the use of soldier feedback to maximize influence on system design; however, it does not provide the methods by which this should be accomplished nor does it specify the metrics or measures for assessing the progress. This case study applies HRLs to an army software modernization program and provides an in-depth analysis of the HSI activities performed and the extent to which they addressed each question in the HRL scales.
Antecedents and Appraisals of Triumph across Four Countries
Authors: Hwang Hyisung C. , Matsumoto David , Yamada Hiroshi , Kostic Aleksandra , Granskaya Juliana
Published: April 2021

This study examined cross-cultural similarities and differences in antecedents and appraisals of triumph. Participants in the U.S., Serbia, Russia, and Japan provided open-ended descriptions of previous antecedent events that elicited experiences of triumph, and completed a standard appraisal questionnaire about those events. Events that elicited pride were also included for comparison. The open-ended responses were coded using a framework that delineated theoretical characteristics of triumph based on previous research. Findings indicated cross-cultural similarities in the antecedents and appraisals of triumph-eliciting events. Cultural variations were also found, especially between Japan and the other cultural groups and with regard to self-evaluations, which suggested the role of culture in triggering and appraising emotion-eliciting events. These findings extended empirical evidence about these important components of triumph, further contributing to its possibility as a discrete emotion.
No Association of Homocysteine, Anticardiolipin Antibody, and Anti-β2 Glycoprotein I Antibody With Portal Venous System Thrombosis in Liver Cirrhosis
Authors: Wang Le , Guo Xiaozhong , Xu Xiangbo , Xu Shixue , Han Juqiang , Wang Ran , Guo Zeqi , Yi Fangfang , Qi Xingshun
Published: April 2021

Portal venous system thrombosis (PVST), a common complication of liver cirrhosis, is closely associated with thrombophilia. To explore the association of homocysteine (Hcy), anticardiolipin antibody (aCL), and anti-β2 glycoprotein I antibody (aβ2GPI), which are possible thrombophilic factors, with PVST in liver cirrhosis. Overall, 654 non-malignant patients (219 with and 435 without liver cirrhosis) admitted between January 2016 and June 2020 were retrospectively evaluated. Presence of PVST, degree of main portal vein (MPV) thrombosis, and clinically significant PVST were identified. Hcy level, hyperhomocysteinemia (HHcy), aCL positivity, and aβ2GPI positivity were compared according to the presence of liver cirrhosis and PVST. Positive aβ2GPI was significantly more frequent in patients with liver cirrhosis than those without, but Hcy level and proportions of HHcy and positive aCL were not significantly different between them. PVST could be evaluated in 136 cirrhotic patients. Hcy level [10.57 μmol/L (2.71-56.82) versus 9.97 μmol/L (2.05-53.44); P = 0.796] and proportions of HHcy [4/44 (9.1%) versus 13/81 (16.0%); P = 0.413] and positive aCL [1/23 (4.3%) versus 10/52 (19.2%); P = 0.185] and aβ2GPI [9/23 (39.1%) versus 21/52 (40.4%); P = 0.919] were not significantly different between cirrhotic patients with and without PVST. There was still no significant association of Hcy level, HHcy, aCL, or aβ2GPI with PVST based on Child-Pugh classification, MPV thrombosis >50%, and clinically significant PVST. Hcy, aCL, and aβ2GPI may not be associated with PVST in liver cirrhosis, suggesting that routine screening for Hcy, aCL, and aβ2GPI should be unnecessary in such patients.
Intelligent fault diagnosis method for common rail injectors based on hierarchical weighted permutation entropy and pair-wise feature proximity feature selection
Authors: Ke Yun , Yao Chong , Song Enzhe , Yang Liping , Dong Quan
Published: April 2021

It is of great significance for intelligent manufacturing to study diagnosis methods to realize the diagnosis of mechanical equipment faults. Multiscale weighted permutation entropy is an effective method recently proposed to measure the complexity and dynamic changes of dynamic systems. To solve the shortcoming of multiscale weighted permutation entropy that does not consider high-frequency components, this article proposes hierarchical weighted permutation entropy, which can comprehensively and accurately reflect the low-frequency and high-frequency information of the time series. The simulation signal verifies the effectiveness and superiority of hierarchical weighted permutation entropy. Then, a novel intelligent fault diagnosis method for common rail injectors based on hierarchical weighted permutation entropy and pair-wise feature proximity is proposed. Finally, the proposed method is applied to the common rail injector fault data, and the results verify the effectiveness of the proposed method. Compared with other methods, this method has a higher fault recognition rate and stronger robustness.
Adaptive control of free-floating manipulator in presence of stochastic input disturbances and unknown dynamical parameters
Authors: Seyed Sakha Masoud , Kharrati Hamed , Mehdifar Farhad
Published: April 2021

The trajectory tracking problem of a free-floating manipulator with dynamical uncertainties and stochastic input disturbances is solved in this study. First, the free-floating manipulator is mapped to a conventional fixed base dynamically equivalent manipulator. Then, by using the well-known properties of a revolute joint manipulator and taking into account the random disturbances with unknown power spectral density in control inputs, an adaptive controller scheme is developed. The proposed technique uses the exponential practical stability concept which guarantees that the tracking error and its derivative converge to an arbitrarily small neighborhood of zero by appropriate tuning of the controller’s parameters. It is noteworthy that the proposed controller does not need any physical parameters of the robot. Simulation studies demonstrate the effectiveness and capability of the proposed method for trajectory tracking in the presence of unknown stochastic input disturbances and dynamical uncertainties.
Child Maltreatment and Substance Use in Emerging Adulthood: Internalizing and Externalizing Behaviors at the Transition to Adolescence as Indirect Pathways
Authors: Olson Anneke E. , Shenk Chad E. , Noll Jennie G. , Allen Brian
Published: April 2021

One well-established outcome of child maltreatment is an increased likelihood of substance use in emerging adulthood. However, research identifying the indirect pathways that explain this relation is lacking, thereby limiting substance use prevention efforts for the child maltreatment population. The present study helped address this gap by accessing data from The Longitudinal Studies on Child Abuse and Neglect (LONGSCAN; n = 1,136), a prospective cohort study of child maltreatment from birth through age eighteen. Internalizing and externalizing problems at age twelve were examined as indirect effects of the relation between child maltreatment prior to age four and substance use at age eighteen. A multiple mediator model tested the total and specific indirect effects of internalizing and externalizing concerns while controlling for demographic risk factors. Results demonstrated that the total indirect effect for internalizing and externalizing behaviors was statistically significant, Standardized Point Estimate = 0.01, 95% CI: 0.00-0.02. Examination of the specific indirect effects revealed that only externalizing behaviors constituted an indirect pathway, Standardized Point Estimate = 0.01, 95% CI: 0.00-0.03. These results suggest that externalizing behaviors at the transition to adolescence are important intervention targets for reducing the risk for substance use in emerging adulthood in the child maltreatment population.
Intervening With Attachment and Biobehavioral Catch-Up to Reduce Behavior Problems Among Children Adopted Internationally: Evidence From a Randomized Controlled Trial
Authors: Yarger Heather A. , Lind Teresa , Raby K. Lee , Zajac Lindsay , Wallin Allison , Dozier Mary
Published: April 2021

Children who have been adopted internationally often exhibit persistent behavior problems. The current study assessed the efficacy of the Attachment and Biobehavioral Catch-up intervention (ABC; Dozier & Bernard, 2019 ) for reducing behavior problems in 122 children adopted internationally. Behavior problems were measured via parent-report using the Brief Infant Toddler Social Emotional Assessment at a pre-intervention visit and after the intervention when children were between 18 and 36 months. Children’s behavior problems were also observed using the Disruptive Behavior Diagnostic Observation Schedule (DB-DOS) after the intervention when children were 48 and 60 months. Parents who received ABC reported fewer child behavior problems than parents who received the control intervention immediately after the intervention through 1.5 years post-intervention. Additionally, children whose parents received ABC exhibited fewer behavior problems within the parent context of the DB-DOS when they were 48 months old (2 years post-intervention) than children whose parents received the control intervention. There were no significant intervention effects on children’s observed behavior problems within the examiner contexts. These results support the efficacy of ABC in reducing behavior problems among children adopted internationally. Trial registration: ClinicalTrials.gov NCT00816621.
Bilateral angle-closure during hospitalization for coronavirus disease-19 (COVID-19): A case report
Authors: Barosco Guido , Morbio Roberta , Chemello Francesca , Tosi Roberto , Marchini Giorgio
Published: April 2021

Purpose:

This report describes a case of bilateral primary angle closure (PAC) progressing to unilateral end-stage primary angle closure glaucoma (PACG) associated with treatment for coronavirus disease-19 (COVID-19) infection.

Methods:

A 64-year-old man came to our attention because of blurred vision after a 2-month hospital stay for treatment of COVID-19 infection. Examination findings revealed PACG, with severe visual impairment in the right eye and PAC in the left eye due to plateau iris syndrome. The patient’s severe clinical condition and prolonged systemic therapy masked the symptoms and delayed the diagnosis. Medical chart review disclosed the multifactorial causes of the visual impairment. Ultrasound biomicroscopy (UBM) aided in diagnosis and subsequent therapy.

Results:

The cause behind the primary angle closure and the iridotrabecular contact was eliminated by bilateral cataract extraction, goniosynechialysis, and myotic therapy.

Conclusions:

COVID-19 treatment may pose an increased risk for PAC. Accurate recording of patient and family ophthalmic history is essential to prevent its onset. Recognition of early signs of PAC is key to averting its progression to PACG.
In Silico Characterization of a Hypothetical Protein from Shigella dysenteriae ATCC 12039 Reveals a Pathogenesis-Related Protein of the Type-VI Secretion System
Authors: Rabbi Md. Fazley , Akter Saiwda Asma , Hasan Md. Jaimol , Amin Al
Published: April 2021

Shigellosis caused by Shigella dysenteriae is a major public health concern worldwide, particularly in developing countries. The bacterial genome is known, but there are many hypothetical proteins whose functions are yet to be discovered. A hypothetical protein (accession no. WP_128879999.1, 161 residues) of S. dysenteriae ATCC 12039 strain was selected in this study for comprehensive structural and functional analysis. Subcellular localization and different physicochemical properties of this hypothetical protein were estimated indicating it as a stable, soluble, and extracellular protein. Functional annotation tools, such as NCBI-CD Search, Pfam, and InterProScan, predicted our target protein to be an amidase effector protein 4 (Tae4) of type-VI secretion system (T6SS). Multiple sequence alignment of the homologous sequences coincided with previous findings. Random coil was found to be predominant in secondary structure. Three-dimensional (3D) structure of the protein was obtained using homology modeling method by SWISS-MODEL server using a template protein (PDB ID: 4J30) of 80.12% sequence identity. The 3D structure became more stable after YASARA energy minimization and was validated by several quality assessment tools like PROCHECK, QMEAN, Verify3D, and ERRAT. Superimposition of the target with the template protein by UCSF Chimera generated RMSD value of 0.115 Å, suggesting a reliable 3D structure. The active site of the modeled structure was predicted and visualized by CASTp server and PyMOL. Interestingly, similar binding affinity and key interacting residues were found for the target protein and a Salmonella enterica Tae4 protein with the ligand L-Ala D-Glu-mDAP by molecular docking analysis. Protein-protein docking was also performed between the target protein and hemolysin coregulated protein 1 of T6SS. Finally, the protein was found to be a unique protein of S. dysenteriae nonhomologous to human by comparative genomics approach indicating a potential therapeutic target. Most pathogens harboring T6SS in their system pose a significant threat to the human health. Many T6SSs and their effectors are associated with interbacterial competition, pathogenesis, and virulency; however, relationships between these effectors and pathogenicity of S. dysenteriae are yet to be determined. The study findings provide a lucrative platform for future antibacterial treatment.
Taking leadership fashions seriously as a vehicle for leadership learning
Authors: Guthey Eric , Ferry Nicole Capriel , Remke Robyn
Published: April 2021

Popularized and commercialized leadership ideas are often criticized as mere fashions that dumb down leadership discourse, research, and learning. By contrast, we take leadership fashions seriously as an important vehicle for individual and collective leadership learning. We extend the neo-institutional theory of management fashions to define leadership fashions as a process that constantly reconfigures the rational norms and expectations attached to leadership, and that elevates certain approaches as the best way to fulfill those norms and expectations. Combining Weber’s broad understanding of rationality with our own concept of affective rationality, we account for the many different instrumental, practical, moral, and sometimes deeply personal and emotional norms and expectations that drive the leadership fashion setting process. This approach contributes a theoretical foundation for understanding the sociological significance of leadership fashions, for exploring the leadership industries that produce and promote them, and for researching further the ways that leadership fashions and the leadership industries influence leadership research, learning, and practice.
Internal conversations, self-reliance and social support in emerging adults transitioning from out-of-home care: An interpretative phenomenological study
Authors: Appleton Peter , Hung Isabelle , Barratt Caroline
Published: April 2021

Young people transitioning from out-of-home care frequently have a history of maltreatment and multiple psychosocial challenges. ‘Survivalist self-reliance’ – thought to involve social disconnection from others, and reluctance to seek support – provides one coping strategy. However, little is known about the self-reliant young person’s own reflexive interpretations of social relationships and support during transition. This qualitative study addresses the question: In the context of transitioning from out-of-home care, what reflexive meanings do ‘avowedly’ self-reliant individuals attribute to current social support and social relationships? Participants were four avowedly self-reliant young adults in transition from care, each with a history of maltreatment and multiple adversities. In this secondary analysis, data were from semi-structured interviews utilizing Margaret Archer’s internal conversations interview framework. Data were analyzed using Interpretative Phenomenological Analysis (IPA). Three thematic contexts were identified in which social support was salient: (a) current thoughts and active memories of both the birth family and foster families; (b) the importance of socializing; and (c) perceptions of formal services. There was evidence of cognitive reappraisal (a known amenable resilience factor) and selective engagement with social support, despite the strong overall stance of self-reliance. The findings suggest a more nuanced approach to our understanding of ‘survivalist self-reliance’.
Teachers’ Narratives of Life Satisfaction, Social Mobility, and Practical Sense of Inequalities in Chile
Authors: Lizama-Loyola Andrea
Published: April 2021

The academic literature argues that understandings of the subjective experience of social mobility differ from objective measure of social mobility – based on occupational patterns of movement – because people tend to conflate changes of the social structure (social change) and changes within the social structure (social mobility), resulting in a limited sense of social inequalities. This article explores subjective understandings of social mobility through the lens of Chilean school-teachers’ narratives of their life trajectories. Methodologically, data were collected through in-depth interviews with 41 teachers who live in Santiago. They were also asked to draw a timeline with the main transitions in their lives. The findings of this article show that teachers’ evaluations of their trajectories are first expressed as narratives relating to their life satisfaction. Differential forms of social comparison that emerge from teachers’ evaluations of their trajectories reveal how people position themselves within a broader structure of social inequalities. In consequence, teachers’ evaluations of their trajectories contain implicit or explicit narratives of social mobility which are often bound up with a subjective sense of social change and life-course change. This article demonstrates that lay understandings of social mobility potentially illuminate academic understandings, by addressing a multidimensional and fluid model of social mobility as well as the practical experiences of inequalities that frame people’s everyday lives.
Navigating a heteronormative world: Cisgender women, transgender partnerships, sexual identity, and language
Authors: Perri Brandi L
Published: April 2021

This article examines the relationship between language and sexual identity, using data collected from in-depth interviews with cisgender women who are in relationships with female-to-male transgender men. The data illustrate that many of the women have complex relationships with the labels that they use to describe their own sexual identity currently and in their past. When referring to their own sexual identities, cisgender women partners of trans men (a) are flexible with specific terms they use in order to respond to varying social contexts, (b) use specific terms to signify cultural belonging to or difference from different communities, and (c) use language as a suggestive action to others to question heteronormative assumptions. Further, this research highlights the importance of considering time in sexuality research, including the timing of the partnerships, and collecting data that reflect the individuals’ histories to analyze the connection between sexual identity and the use of language.
From self-evident norms to contingent couplings: A systems-theoretical analysis of changes in the relationship between schools and the function systems in Denmark
Authors: Andersen Niels Åkerstrøm , Pors Justine Grønbæk
Published: April 2021

Taking a point of departure in the paradoxical fact that the increase in educational knowledge leads to an increase in uncertainty for educational organisations, this article explores how uncertainty and contingency have increasingly become an integral part of school governance. The article draws on Niklas Luhmann’s theory of ‘World Society’ as a functional differentiated society providing a range of different symbolic media for educational organisations. To trace the increase in the complexity of governing, we provide a historical account of the shifting couplings between schools and function systems. We show how the school becomes linked to an increasing number of symbolic media so that education becomes only one out of many other concerns. The article studies the consequences these shifting couplings have for how schools are governed and how they are expected to self-manage their relationship to different function systems.

The article adds to existing studies of how education has become more and more differentiated with the argument that this has also led to new forms of couplings between schools and the education system with a number of important implications for the teaching profession.
Two decades of European criminology: Exploring the conferences of the European Society of Criminology through topic modelling
Authors: Vander Beken Tom , Vandeviver Christophe , Daenekindt Stijn
Published: April 2021

What is European criminology about? Through topic modelling, we investigate the content of 11,724 presentations held at the annual conferences of the European Society of Criminology, the largest and most influential professional association in Europe for those who are actively engaged in research, teaching, and/or practice in criminology, from 2001 to 2019. We extract 50 topics and identify the top contributing institutions and countries based on first author institutional affiliation. In addition, we determine the most and least influential topics in European criminology. We further explore how the prominence of topics has evolved over time and identify five topics that are increasingly being addressed and three topics that have gradually declined in interest – hot and cold topics, respectively. The results are discussed in light of previous research on European criminology and current debates on its epistemology.
Border U
Authors: Gildersleeve Ryan Evely , Sifuentez Brenda Jimenez
Published: April 2021

In this paper, we take an ontological approach to examining the university as an object of activism. We speculatively theorize a Border University and a Border U. A Border University understands and explains academic policy and policy regimes as a bordering practice expressed through technologies that govern the flow and junctures of social movement. The Border U that we theorize centers the lives and contributions of Latinx (im)migrant communities. Border U emerges through activist opposition to the dominant Border University. In speculating Border University and Border U, we draw heavily upon Thomas Nail’s ontology of motion, theory of the border, and figure of the migrant. Recasting the university within an ontology of motion allows new possibilities for building anew a social institution that can tackle the persistent problems of the past, reconciling them in the present, and preparing for the future, as we try to illustrate in the case of Latinx (im)migrant communities in US higher education.
Intervention Strategies and Lessons Learned From a Student-Led Initiative to Support Lactating Women in the University Setting
Authors: Bell Emily , Hunter Cristina , Benitez Trista , Uysal Jasmine , Walovich Carey , McConnell Leah , Vega Christine , Cisneros Nora , Hidalgo LeighAnna , Reyes Walton JoAnna , Wang May
Published: April 2021

The benefits of breastfeeding for mother and baby are strongly supported by research. However, lactating parents who return to school or work soon after delivery face many barriers to continued breastfeeding. This article presents a student-led initiative to support lactation at a large public university that emerged from advocacy efforts of student mothers of color. The socioecological model was used as a framework to understand and address the multifaceted influences on breastfeeding practices. Project activities included providing breastfeeding education to lactating parents and their partners, measuring availability and accessibility of lactation spaces, improving lactation spaces, connecting university stakeholders, and strengthening university lactation policies. The project achieved the following outcomes: formation of a stakeholder group with members across campus departments, improvement in accessibility and appropriateness of lactation spaces, provision of breastfeeding services through workshops and one-on-one appointments with lactation educators, and creation and dissemination of an online toolkit outlining parents’ lactation rights and support available on campus. Comprehensive lactation support at universities is essential to enhance educational and professional equity for women and to promote postpartum and infant health. Throughout the project implementation, the team learned many lessons that can help guide similar university initiatives.
Historical Drama in the Time of Global Streaming Platforms: Envisioning Transition in Mr. Sunshine
Authors: Kim Yaeri
Published: April 2021

This article examines 2018 South Korean historical drama Mr. Sunshine as an example showcasing the impact of global streaming platforms on local television production. As a locally produced show targeting the international market and later purchased by Netflix, Mr. Sunshine offers an interesting case study of the local industry’s response to changes brought about by global streaming services. This article analyzes how the creators’ acute awareness of the threats and opportunities posed by the increasingly transnationalizing media industry is reflected in the text of the historical drama set in the time of modernization and the approaching Japanese occupation. It argues that Mr. Sunshine’s visual and narrative construction of early twentieth-century Korea, which emphasizes the unrealized potential of transitional times and Korean people’s agency in shaping their own history, indicates a perceived parallel between the setting of the show and the conditions of its creation.
Evaluation of the Evidence Base for Shared Reading to Support Literacy Skill Development for Students with Extensive Support Needs
Authors: Toews Samantha Gross , McQueston Jessica , Kurth Jennifer A.
Published: April 2021

This systematic literature review updates and extends the findings of Hudson and Test’s 2011 review of literature on shared reading, an interactive read-aloud practice, to promote literacy skills for students with extensive support needs (ESN). Thirty-two shared reading studies are assessed and described in terms of literacy skills investigated, intervention methods, materials used, interventionists, and settings in which shared reading has been evaluated for students with ESN. The quality of each included study was analyzed and the assessment of level of research evidence was conducted using systematic processes. Results indicate that there is a moderate level of evidence for shared reading as an intervention to promote comprehension, vocabulary, and emergent literacy skills for students with ESN. Implications for practice and areas of need for future research are presented.
The Heroine’s/Hero’s Journey—A Call for Transformation? Transformative Learning, Archetypal Patterns, and Embodied Knowing/Learning
Authors: Lehner Daniela
Published: April 2021

This article explores the phenomena of personal transformation within the frame of a self-experiential workshop, named the Heroine/Hero’s Journey. The Heroine/Hero is the archetype who sets out on an adventurous journey, in pursuit of her or his call for transformation. Rebillot based on Campbell’s (1949) mythological work, The Hero with a Thousand Faces created an experiential approach in the form of a one-week workshop, which utilizes methods from theatre and Gestalt therapy. This phenomenologically oriented vignette research draws on interviews and co-experienced observations, which were conducted during the workshop in order to explore the participants’ experiences and the content of participants’ transformation. The embodied representation of personality patterns, conscious and unconscious and especially the confrontation of these patterns, created transformative experiences for the participants. The depth psychological understanding of transformative processes, highlighting the potential of embodied and archetypal ways of knowing, provides the theoretical frame for giving meaning to these experiences.
Gunshot Injuries of the Hand: Incidence, Treatment Characteristics, and Factors Associated With Healthcare Utilization
Authors: Anantavorasakul Navapong , Westenberg Ritsaart F. , Serebrakian Arman T. , Zamri Meryam , Chen Neal C. , Eberlin Kyle R.
Published: April 2021

Background

The objectives of this study are to: (1) describe the demographics, injury patterns, and treatment characteristics of patients who sustained a gunshot injury (GSI) of the hand; and (2) examine the utilization of healthcare resources in patients with a GSI of the hand.

Methods

We retrospectively identified 148 adult patients who were treated for a GSI of the hand between January 2000 to December 2017 using multiple International Classification of Diseases Ninth and Tenth Edition (ICD-9 and ICD-10) codes. We used bivariate and multivariable analysis to identify which factors are associated with unplanned reoperation, length of hospitalization, and number of operations.

Results

Multivariable logistic regression showed that fracture severity was associated with unplanned reoperation. Multivariable linear regression showed that fracture severity is associated with a higher number of hand operations after a GSI of the hand, and that a retained bullet (fragment) and patients having gunshot injuries in other regions than the hand had a longer length of hospitalization. Seventy (47%) patients had sensory or motor symptoms in the hand after their GSI, of which 22 (15%) patients had a transection of the nerve.

Conclusions

Sensory and motor nerve deficits are common after a GSI of the hand. However, only 31% of patients with symptoms had a transection of the nerve. A retained bullet (fragment), having more severe hand fractures, and GSI in other regions than the hand are associated with a higher number of operation and a longer period of hospitalization.
A Hybrid Value-Based Lifestyle Medicine Practice Model
Authors: Dysinger Wayne S.
Published: April 2021

A lifestyle medicine approach to primary care that is value based can provide positive triple aim outcomes and demonstrate market equivalent reimbursement for the practitioner.
Ultrasonic dispersion method used in glass polishing experiment
Authors: Chu Zenan , Wang Tao , He Qiang , Zhao Kai
Published: April 2021

To solve the problems of low processing efficiency and poor glass surface quality when using rare earth polishing powder to grind super-hard K9 glass. The potential, phase structure, surface morphology, and particle size distribution of the nano-rare earth polishing powder were characterized. Compare the evaluation indexes such as polishing efficiency, surface morphology, and contact angle after the polishing process is changed. The results of the comparative study show that the average surface roughness of the glass after heating ultrasonic polishing process is 0.9064 nm, the polishing rate reaches 0.748 μm/min, the average surface roughness of the glass without heating ultrasonic polishing process is 1.3175 nm, and the polishing rate reaches 0.586 μm/min, the ultrasonic assisted polishing process is superior to the conventional polishing process. The heating ultrasonic method provides experimental basis for precise and rapid processing.
The role of functional polymorphisms in oxidative stress-related genes on early-stage breast cancer survival
Authors: Korobeinikova Erika , Ugenskiene Rasa , Insodaite Ruta , Rudzianskas Viktoras , Gudaitiene Jurgita , Juozaityte Elona
Published: April 2021

Background:

Genetic variations in oxidative stress-related genes may alter the coded protein level and impact the pathogenesis of breast cancer.

Methods:

The current study investigated the associations of functional single nucleotide polymorphisms in the NFE2L2, HMOX1, P21, TXNRD2, and ATF3 genes with the early-stage breast cancer clinicopathological characteristics and disease-free survival, metastasis-free survival, and overall survival. A total of 202 Eastern European (Lithuanian) women with primary I–II stage breast cancer were involved. Genotyping of the single nucleotide polymorphisms was performed using TaqMan single nucleotide polymorphisms genotyping assays.

Results:

The CA+AA genotypes of P21 rs1801270 were significantly less frequent in patients with lymph node metastasis and larger tumor size ( P=0.041 and P=0.022, respectively). The TT genotype in ATF3 rs3125289 had significantly lower risk of estrogen receptor (ER), progesterone receptor (PR) negative, and human epidermal growth factor receptor 2 (HER2) positive status ( P=0.023, P=0.046, and P=0.040, respectively). In both, univariate and multivariate Cox analysis, TXNRD2 rs1139793 GG genotype vs. GA+AA was a negative prognostic factor for disease-free survival (multivariate hazard ratio (HR) 2.248; P=0.025) and overall survival (multivariate HR 2.248; P=0.029). The ATF3 rs11119982 CC genotype in the genotype model was a negative prognostic factor for disease-free survival (multivariate HR 5.878; P=0.006), metastasis-free survival (multivariate HR 4.759; P=0.018), and overall survival (multivariate HR 3.280; P=0.048).

Conclusion:

Our findings suggest that P21 rs1801270 is associated with lymph node metastasis and larger tumor size, and ATF3 rs3125289 is associated with ER, PR, and HER2 status. Two potential, novel, early-stage breast cancer survival biomarkers, TXNRD2 rs1139793 and ATF3 rs11119982, were detected. Further investigations are needed to confirm the results of the current study.
A Bayesian dose-finding design for outcomes evaluated with uncertainty
Authors: Schipper Matthew J , Yuan Ying , Taylor Jeremy MG , Ten Haken Randall K , Tsien Christina , Lawrence Theodore S
Published: April 2021

Introduction:

In some phase I trial settings, there is uncertainty in assessing whether a given patient meets the criteria for dose-limiting toxicity.

Methods:

We present a design which accommodates dose-limiting toxicity outcomes that are assessed with uncertainty for some patients. Our approach could be utilized in many available phase I trial designs, but we focus on the continual reassessment method due to its popularity. We assume that for some patients, instead of the usual binary dose-limiting toxicity outcome, we observe a physician-assessed probability of dose-limiting toxicity specific to a given patient. Data augmentation is used to estimate the posterior probabilities of dose-limiting toxicity at each dose level based on both the fully observed and partially observed patient outcomes. A simulation study is used to assess the performance of the design relative to using the continual reassessment method on the true dose-limiting toxicity outcomes (available in simulation setting only) and relative to simple thresholding approaches.

Results:

Among the designs utilizing the partially observed outcomes, our proposed design has the best overall performance in terms of probability of selecting correct maximum tolerated dose and number of patients treated at the maximum tolerated dose.

Conclusion:

Incorporating uncertainty in dose-limiting toxicity assessment can improve the performance of the continual reassessment method design.
Testing Meldonium: Assessing Soviet pragmatic alternatives to the randomized controlled trial
Authors: Chirkova Anastasiya , Petrenko Alexander , Vasilyev Pavel
Published: April 2021

Background/aims

Current research largely tends to ignore the drug-testing model that was developed in the “Second World” as an explicit alternative to the randomized controlled trial. This system can be described as “socialist pharmapolitics,” accounting for the specific features of state socialism that influenced the development and testing of experimental drugs. The clinical trials model employed in the “Second World” was heavily influenced by the Soviet Union, which was by far the most influential player in the socialist bloc during the Cold War. Based on extensive archival research, this article presents an empirical case of a late Soviet clinical trial as a pragmatic alternative to the randomized controlled trial model. It accounts for the divergences between the official model prescribed by the Soviet authorities and the messy realities of healthcare practice. It further outlines different factors that ultimately shaped how clinical trials were organized in Soviet institutions “on the ground.” Accordingly, this article presents a “real-life” history of “socialist pharmapolitics” and outlines the problems that this system faced in practice.

Methods

Archival research was conducted at the Russian State Archive of Scientific and Technical Documentation in Moscow. Archival files include scientific, technical, and registration documentation such as biochemical, pharmacological, and clinical descriptions of the experimental drug Meldonium, letters between various hospitals, research institutes and the Soviet regulatory body, as well as 26 reports of completed clinical trials. Manual content analysis was used for the interpretation of results.

Results

This article presents an empirical case of a late Soviet clinical trial as a pragmatic alternative to the randomized controlled trial model. It demonstrates some key differences from the randomized controlled trial model. This article also highlights some of the discrepancies between the model that was officially prescribed by the Soviet authorities and the realities of experimental drug testing in the Soviet Union in the late 1980s and early 1990s. In particular, it notes some elements of randomization, double-blinding, and the use of placebo that were present in Meldonium trials despite being formally denounced by Soviet bioethics.

Conclusion

The Soviet model for testing experimental drugs differed from the Western one substantially in a number of respects. This difference was not only proclaimed officially by the Soviet authorities, but was for the most part enforced in clinical trials in practice. At the same time, our research demonstrates that there were important differences between the official model and the clinical realities on the ground.