bluuebunny/crossref_metadata_2025 huggingface dataset:
ISAR Pulses Reconstruction and High-resolution Imaging via Frequency-selective Reweighted Atomic Norm Minimization
Authors: Zhang Tao , Wang Sui , Lai Ran
Published: July 2024

Receiving incomplete signals is common in real inverse synthetic aperture radar (ISAR) imaging. If incomplete signals are used for imaging, severe grating lobes will be present in the obtained image. The gridless sparse recovery (SR) method, called atomic norm minimization (ANM), can reconstruct missing signals accurately and is particularly well-suited for sparse ISAR imaging. The Frequency-selective (FS) ANM (FSANM) method uses prior knowledge to improve the estimation performance of the ANM method. However, the estimated performance of the FSANM method is still limited by convex relaxation when frequency separation is unreasonable, which leads to unsatisfactory imaging results. To break this limitation and improve ISAR imaging performance, a novel gridless sparse ISAR imaging method was proposed, which can be called FS reweighted ANM (FSRAM). The proposed method introduces a non-convex metric to establish a connection between atomic \({\ell _0}\) norm and \({\ell _1}\) norm. According to the non-convex iterative solution model, the implementation of a semi-definite program (SDP) for FSRAM was derived. The simulated experimental results indicate that the proposed method maintains a high level of estimate performance even in cases when the frequency separation is not acceptable. The real experimental results show that the proposed method can obtain better quality ISAR images.
The application of self-made liver suspension device in 3D laparoscopic non-anatomical resection of liver VI and VII segments tumors
Authors: Chen Shengxiong , Jin Xiaoxu , Hao Zijia , Wang Yijun , Du Chengxu , Liu Xiaoding , Jiang Huiqing
Published: July 2024

Objective: To investigate the effect of self-made liver suspension device in 3D laparoscopic non-anatomical resection of liver VI and VII segments tumors.
Methods: The clinical data of 79 patients who underwent non-anatomical resection of liver VI and VII segments tumors at the Second Hospital of Hebei Medical University from June 2016 to June 2022 were retrospectively analyzed, divided into SDLG group and CLG group. The SDLG group used the self-made liver suspension device for 3D laparoscopic resection, and the CLG group received conventional 3D laparoscopic resection; the clinical data were compared to evaluate the efficacy.
Results: The operation time in SDLG group was significantly shorter than that in CLG group, the intraoperative bleeding volume and liver portal blockage time were significantly reduced, and the postoperative complications were alleviated; there was no significant difference in hospital stay, drainage tube removal time, bedside time, and postoperative flatus time.
Conclusion: The self-made liver suspension device can shorten the operation time and liver portal blockage time, reduce intraoperative bleeding, alleviate postoperative complications, and improve the safety of non-anatomical resection of liver VI and VII segments tumors. It is worth further clinical promotion.
Evaluation of dental implant with hydroxyapatite coating by laser-induced hydrothermal synthesis: in vitro and in vivo experimental study
Authors: Lee Jung-Tae , Kim Sungtae , Lee Sung-Ho , Han Dong-Wook , Kwon Daehyeok , Lee Kyungwoo , Jeon Hojeong , Jung Tae-Gon , Kim Bongju
Published: July 2024

Various attempts to increase the survival rate of dental implant have been introduced. Among the, there have been many studies for modification of implant surfaces. This study aimed to evaluate the results of in vitro and in vivo experiments on implants using a nano/micro-assembled hydroxyapatite (HA) structure with laser-induced single-step coating (LISSC) technique. In this study, machined surface implants (MA), sandblasted, large-grit, acid-etched surface implants (SLA), resorbable blasting media surface implants (RBM), and hydroxyapatite surface implants (HA) were used. Surface morphology, surface hydrophilicity and cell attachment analysis were conducted (in vitro). Twelve rabbits and two beagles were used in this in vivo study. Immediately after placement, the implant stability quotient (ISQ) was measured using the Osstell mentor device. After the animals were sacrificed (rabbit: 3 and 6 weeks; beagle: 12 weeks), histological, bone-implant contact ratio (BIC%), and bone volume ratio (BV%) analyses were performed. The ISQ value increased from post-OP to 6 or 12 weeks for all animal implant types. The results of in vitro experiment were shown as follows: “HA > RBM > SLA > MA (roughness value)” and “RBM > HA > MA > SLA (surface wettability)”. There were no statistically significant differences in initial cell adhesion and viability among four groups (cell attachment). According to the in vivo results, BV were measured in the order “SLA > RBM > HA > MA (3-week)” and “SLA > HA > RBM > MA (6-week)”. For BIC, the results were as follows: RBM > HA > MA > SLA (3 weeks) and HA > RBM > SLA > MA (6 weeks). HA showed the greatest increases in BV and BIC from 3 to 6 weeks (HA > SLA > RBM > MA). In the beagle experiment, the ISQ value at 12 weeks was higher than that post-OP for both HA and SLA. HA was higher than SLA in the BV group. HA implants act at a similar or equivalent level to other implants (MA, SLA, and RBM).
A survey on sugarcane mosaic symptoms leads to the first report of sugarcane chlorotic streak virus in Cameroon
Authors: Daugrois Jean-Heinrich , Ahondopké Benoît , Galzi Serge , Julian Charlotte , Filloux Denis , Rott Philippe C. , Roumagnac Philippe
Published: July 2024

Four sugarcane leaf samples from Cameroon showing mosaic like symptoms tested negative by RT-PCR for potyviruses and a poacevirus causing mosaic in sugarcane. Virus sequences sharing 98–99% nucleotide identity with Sugarcane chlorotic streak virus from Nigeria were found in these four samples by virion-associated nucleic acid metagenomics. Five complete genome sequences were obtained after cloning five isolates from Cameroon. These genome sequences shared less than 75–76% identity with the closest Mastrevirus species, thus confirming that Sugarcane chlorotic streak virus is a new Mastrevirus species. To our knowledge, this is the first report of Sugarcane chlorotic streak virus in Cameroon.
Reasons for boosting HIV testing and association with risky sexual behaviors in MSM population: evidence from China
Authors: Zhang Xingliang , Wang Shuo , Xu Ke , Xu Junfang
Published: July 2024

Background: A regular human immunodeficiency virus (HIV) testing with a safe sexual behavior is an important preventive strategy in the control of HIV especially among men who have sex with men (MSM), who are in risk of HIV infection. Therefore, we aim to explore the reasons boosting HIV testing among MSM and the risky sexual behaviors behind.
Methods: An institutional based investigationwas conducted to collect data from MSM in January and December 2022in Zhejiang Coastal Public Welfare Center which is a non-government organization (NGO). The risky sexual behaviors included commercial sexual behaviors, unprotected sexual behaviors, multiple sexual partners, drug using and using sexual stimulant. The reasons for boosting MSM to have HIV testing included prevention before/after exposure, regular habit testing high risk post testing, peer driven testing, publicity and education testing and others. The factors influencing the unprotected sex, multiple sexual partners, using drugs and sexual stimulants of MSM were explored based on multivariate logistic regression.
Results:In total, 7266 MSM were incorporated in the analysis. The most important reason for boosting MSM to have an HIV testing were their regular habit testing(51.73%) followed by high risk post test (15.99%), publicity and education testing(12.72%). The population who had high risk post HIV test had the highest percentage of unprotected sex(78.83%), commercial sex(0.84%), using drugs(4.22%) and sexual stimulant(42.0%), multiple sexual partners(30.98%) and symptoms or diagnosis of sexual transmitted diseases (6.11%) compared with MSM with other HIV testing reasons respectively. Compared with the reasons for HIV testing of prevention before/after exposure, people with high-risk post testing had a higher probability of having unprotected sex (P<0.001, OR=5.804) and multiple sexual partners (P=0.041, OR=1.476). Publicity and education testing had a lower probability of having unprotected sex (P<0.001, OR=0.432) and multiple sexual partners (P=0.006, OR=0.575).
Conclusions: Reasons for boosting HIV testing among MSM were different with different risky sexual behaviors, and the rate of having risky sexual behaviors among MSM with regular HIV testing habits was lower. However, most MSM have not developed the habit of regular HIV testing. Therefore, improving the HIV testing among MSM is still important to reduce the transmission of HIV.
Polypyrrole deposited on the core-shell structured nitrogen doped porous carbon@Ag-MOF for signal amplification detection of chloride ions
Authors: Zhai Xiurong , Li Qian , Cao Yang , Han Mengjie , Sun Hailian , Du Lelin , Yang Xiyun , Wei Yuxin , Yu Congcong
Published: July 2024

A electrochemical platform for signal amplification probing chloride ions (Cl−) was fabricated based on the composite integrating core-shell structured nitrogen doped porous carbon@Ag-based metal-organic frameworks (NC@Ag-MOF) with polypyrrole (PPy). NC@Ag-MOF was firstly synthesized with NC as the scaffold. Then, PPy was anchored on NC@Ag-MOF by chemical polymerization, so that PPy could be applied to disperse NC@Ag-MOF, and effectively improve the conductivity and stability of Ag-MOF. The composite NC@Ag-MOF-PPy was utilized to modify electrode, which could exhibit a higher peak current and lower peak potential during Ag oxidation compared with those of Ag-MOF and NC@Ag-MOF-modified electrodes. More importantly, in the coexistence of chloride (Cl−) ions in solution, NC@Ag-MOF-PPy-modified electrode could display a fairly stable and sharp peak of solid-state AgCl with the peak potentials gradually approaching to zero, which might effectively overcome the background interference caused by electroactive substances. Meanwhile, the oxidation peak currents of solid AgCl can increase linearly for the quantitative of Cl− ions in a broad range of 0.15 µM-250 mM with an low detection limit of 0.10 µM. Furthermore, the feasibility of practical applicability for Cl− ions evaluation was demonstrated in the actual samples of human serum and urine with good consequence. Therefore, these results suggest that NC@Ag-MOF-PPy composite could be a promising candidate for the construction of the electrochemical sensor.
Inaudible airborne ultrasound affects emotional states in the olfactory bulbectomized rat depression model
Authors: Yamauchi Tsugumi , Takahashi Kou , Yoshioka Toshinori , Yamada Daisuke , Nakano Yoshio , Kasai Satoka , Iriyama Satoshi , Yoshizawa Kazumi , Nishino Shoichi , Miyazaki Satoru , Saitoh Akiyoshi
Published: July 2024

Recently, exposure to sounds including ultrasound (US) components has been shown to modulate brain activity. However, the detailed US effects on emotional states remain unclear. We previously demonstrated that olfactory bulbectomized (OBX) rats, a widely used depression model are suitable for examining the effects of high-frequency audible sound on emotionality. Here we investigated the impact of inaudible US exposure on the emotional state of OBX rats. Exposure to 100 kHz US for one h did not affect the number of c-Fos-positive cells in auditory-related cortical areas, suggesting that this frequency is inaudible to rats. However, 12- and 24-h exposures to 100 kHz US improved hyperemotionality (HE) scores in OBX rats accompanied by a decrease in the plasma corticosterone levels, suggesting ameliorative effects on depression-like symptoms and stress. In contrast to HE scores, US exposure did not influence anxiety-like behaviors in the elevated plus maze. In conclusion, we demonstrated that exposure to 100 kHz US could alleviate depressive-like symptom in the OBX rat depression model. This is the first study to show that airborne US alone exposure produced the changes in emotional states in animal model. Future research is necessary to elucidate the underlying mechanisms and determine the optimal treatment regimens.
Development of Sequential Winning Percentage Prediction Model for Badminton Competitions: Applying the Expert System Sequential Probability Ratio Test
Authors: Jo Eunhye
Published: July 2024

Background
This study developed a sequential winning-percentage prediction model for badminton competitions using the expert system sequential probability ratio test (EXSPRT), aiming to calculate the difficulty of each event within a match and establish the initial prior probability.
Methods
We utilized data from 100 men's singles matches (222 games) held by the Badminton World Federation (BWF) in 2018 to evaluate event difficulty across six models for each determining factor. For setting the initial prior probability calculation method, 30 men's singles matches (74 games) organized by the BWF in 2019 were randomly selected. The odds for these matches were obtained from www.oddsportal.com.
Results
The efficacy of the six models was assessed based on application rates (15%, 20%, 25%, and 30%) of the collected odds, with the initial prior probability reflecting 25% of the odds chosen owing to its superior validity.
Conclusions
This research yielded six sequential winning percentage prediction models capable of offering real-time predictions during matches in badminton competitions by leveraging EXSPRT. These models enhance spectator engagement and provide foundational data for developing similar prediction models for other sports. Future research should focus on developing a program to identify the most effective model among the six and implement it practically.
measuring socio-economic inequality in utilization of type 2 diabetes services
Authors: Torabipour Amin , Karimi Saeed , Amini-Rarani Mostafa , Gharacheh Laleh
Published: July 2024

Introduction: Health inequities are important issue; this study was conducted in order to measuring socio-economic inequality in utilization of type 2 diabetes services.
Methods: This study is an explanatory sequential mixed method that was conducted in two Quantitative and Qualitative phases. In the Quantitative part, type 2 diabetes patients referred to health centers, hospitals and diabetes clinics in Isfahan and Khuzestan provinces were selected through available samples. Using the Concentration Index(CI) approach, the existence of inequality in utilization of type 2 diabetes services was examined. In the next step, in order to analyze the inequality, the inequality contribution of each of the determining factors was determined by concentration index analysis method. Next step, we conducted in-depth interviews with key experts in the field of health to extracted effective solutions.
Results: most of the samples were 1306 (65.3%) men. The most age group involved was799 people (40%) over 60 years. concentration index value in outpatient services was 0.31 (p<0.05), inpatient services -0.10 (p>0.05), and pharmaceutical services 0.11 (p<0.05). This means that there was a disparity in the use of outpatient and drug services for type 2 diabetic patients, while the disparity in inpatient services is not significant.
Variables contributing to inequality for outpatient services were health status (33.54%), basic insurance (27.43%) and socio-economic status (24.08%), also in pharmaceutical services, health status variable (22.20%), basic insurance (13.63%) and socio-economic status (34.35%) contributed to socio-economic inequality in utilizing from services related to type 2 diabetes patients. Also, the experts' point of view for solutions to reduce socio-economic inequalities in Iran were classified in 3 main themes (socio-economic status, health status, basic insurance) and 29 sub-themes.
Conclusion: According to the results, it is suggested that targeted health interventions for the poor patient, and the efforts towards outpatient and medicinal items insurance coverage for type 2 diabetic patients. Improving the status of variables affecting of socio-economic inequality in type 2 diabetic patients and improving the status of the country's health system, strengthening the package of basic health insurance utilization.
A Renewable, Green, and Scalable Polyacrylic Polyol (PAMO) Derived from Olive Oil for Transparent Polyurethane Coatings
Authors: Salarvand Ehsan , Omrani Ismail , nabid Mohammad reza , Salehi Milad
Published: July 2024

To prepare a transparent polyurethane coating, a renewable, green, and scalable polyacrylic polyol (PAMO) was synthesized from olive oil (OO) and applied as a polyol. To prepare PAMO, the olive oil was first methanolized using methanol, and methyl oleate (MO) was obtained, followed by its getting epoxidized by formic acid and hydrogen peroxide. Epoxidized methyl oleate (EMO) was ring-opened using acrylic acid (AA) with excellent yield. Further, to prepare PAMO, radical polymerization method was utilized. FT-IR, 1HNMR, and gel permeation chromatography (GPC) verified the chemical structures of the synthesized monomer and polymer. Different thermoset aliphatic transparent polyurethane coatings were obtained by reacting the synthesized polyol with hexamethylene diisocyanate (HDI), isophorone diisocyanate (IPDI), Desmodur N3390, and Desmodur Z4470. The best results were obtained using Desmodur Z4470 as the curing agent. Polyurethane obtained from PAMO and Desmodur Z4470 was acquired in three NCO/OH ratios of 0.9, 1, and 1.2, with the 1.2 NCO/OH ratio as the best-obtained result. The new polyol architecture has emerged as a new polyacrylic polyol and transparent polyurethane coatings class.
Identification of bioactive compounds and potential mechanisms of fuzi in the treatment of ulcerative colitis by integrating network pharmacology and experimental validation
Authors: Ma Miaomiao , Liang Leshi , Lin Meihong , Luo Canhua , Deng Xingfeng , Yu Changhui
Published: July 2024

Background
Ulcerative colitis (UC) is a chronic, non-specific inflammatory bowel disease with a high recurrence rate. Given that no efficient treatment for UC is currently available, there is an urgent need for novel therapeutic strategies. Fuzi, as a traditional Chinese medicine, has anti-inflammatory and immunomodulatory properties. However, the bioactive compounds and mechanisms of fuzi in the treatment of UC are not completely understood.
Method
The active components of fuzi were retrieved from TCMSP; PharmMapper was used to predict the target of the active components of fuzi; UC-related disease targets were obtained from OMIM and Genecards databases, and Venny2.1 was used to intersect with fuzi to obtain common targets; KEGG and GO were performed on the common targets using R 4.0.2. String, Cytoscape3.9.0 was used to construct a protein interaction network for the intersection target. We then determined the role of the candidate molecule from fuzi, Higenamine (Hig), in a mouse model of DSS-induced colitis.
Result
Totally 21 active components and 420 corresponding targets of fuzi were obtained, of which 224 common targets were identified by intersecting with UC-related targets. The GO, KEGG, and PPI results suggested that fuzi and Hig may target AKT1 to regulate the PI3K/AKT pathway in UC. Animal experiments have shown that Hig treatment greatly reduced DSS-induced colitis, as measured by the DAI score, colonic inflammation, and intestinal barrier integrity. Mechanistically, Hig downregulated the DSS-induced PI3K-AKT signaling pathway by inhibiting AKT phosphorylation.
Conclusion
Fuzi may treat UC through multiple components, targets, and pathways. The active component Hig is likely to play a role in the treatment of UC. Hig alleviated DSS-induced colitis in mice, possibly by inhibiting colon inflammation, reducing colon neutrophilic infiltration, and improving the intestinal barrier by regulating the PI3K-AKT signaling pathway.
Implementation of the magnetic Barkhausen noise technique for microstructural characterization of rail steel
Authors: Carvalho Jaime Alberto Jaramillo , Sanchez Juan Camilo , Bustamante Fabio Alexander Suárez , Cortes Daniel Gonzalo Vargas , Quiroz Luis Gonzalo Vargas , Toro Alejandro , Grijalba Freddy Armando Franco
Published: July 2024

In the present work the feasibility of using Magnetic Barkhausen Noise (MBN) to identify variations in the microstructure of a commercial rail steel has been studied. To achieve this purpose a brand new rail, reference R260 was sectioned to obtain two samples that were subjected to quenching and normalizing heat treatments. The hardness and microstructure of the specimens were evaluated by conventional destructive and nondestructive evaluation. The MBN technique's sensibility to characterize different microstructures was studied, and the results were contrasted with hardness and residual stress measurements. The envelope of MBN signals proved to be useful to detect the presence of martensite at the surface of rail sections, mainly because of the high density of dislocations that is typical of this micro constituent in comparison with pearlite of ferrite. The MBN signals showed strong correlation with the changes in hardness and microstructure of the samples, being the normalized sample the one with the highest amplitude signal of MBN. In contrast, the quenched sample with martensite microstructure had a lower MBN intensity. The results of this work show the potential of MBN for nondestructive evaluation (NDE) of rails in the field, which could improve the capacity of early detection of defects in railway systems.
Enhancing Gas Burner Efficiency and Reducing Exhaust Emissions: An Experimental Study on the Use of Nebulized Carbon Nanoparticles
Authors: Jodat Amin , Najafian Mojtaba , Mahian Omid
Published: July 2024

Natural gas is a significant energy source that burns more cleanly than other fossil fuels when used in combustion chamber. Although it is the most environmentally friendly fossil fuel, the radiation heat transfer of its flame is lower than that of liquid and solid fuels, where radiation remains an important factor in heat transfer. This study involved an experiment to examine the impact of injecting nebulized carbon nanoparticles into a natural gas diffusion flame on the radiation characteristics and pollutant emissions of natural gas. The experiments and measurements were conducted by using a three-pass fire tube industrial steel boiler with a maximum capacity of 120 kW. A novel aspect of our experiment was the use of nebulizer technology to inject 1000 ppm of carbon nanoparticles at a mass flow rate of 5.5 g/min into natural gas burners, aiming to improve thermal efficiency and decrease environmental pollutants. Flame radiation heat flux and luminosity were measured using an HFS01 water-cooled heat flux sensor and a TES-1332A digital luminance meter, respectively. The findings indicate that changes in flame properties, such as brightness and heat radiation, are linked to the infrared wavelengths emitted from the flame, as well as to a 2-degree Celsius increase in water temperature at the boiler outlet. Injecting nanoparticles also lowers the chimney gas temperature while enhancing the radiation heat flux by 5%. Despite a slight decrease in the average flame temperature, this technique successfully reduces thermal NOx emissions by 8% and carbon monoxide emissions by 9%, as detected by a Testo 350 XL gas analyzer. It is important to note that this research underscores the potential benefits of using carbon nanoparticle injection to enhance burner efficiency and reduce the environmental impact of natural gas combustion.
Tropical cyclone risk to global electricity supply
Authors: Hall Jim , Thomas Fred , Mo Yu , Rui Jianan , Russell Tom , Robertson Max , Verschuur Jasper , Pant Raghav
Published: July 2024

To analyse the risks from Tropical Cyclones (TC) to electricity supply, we have combined a large ensemble of TC simulations with a spatial model of power networks and people served, for the entire TC belt globally. The model of electricity power failure, measured in terms of population disrupted, was calibrated against nighttime lights satellite imagery of historic TC events. Use of spatially coherent TC simulations enabled the calculation of electricity supply losses at national, regional and global scales for a range of return periods.We estimate that between 65 and 80 million people lose electric power with a return period of 1 in 100 years, depending on the TC model. Most regions show a worsening of TC-induced outages under climate change (RCP8.5 2050), except for the North Indian Ocean, where there is disagreement between TC models. Climate model uncertainty (across four GCMs) influences the estimated global population at risk by a factor of 0.91-1.05 in 2050.
Exploration von Zusammenhängen zwischen polygenem Risikoscore und phänotypischer Ausprägung bei Patienten mit genetisch generalisierter Epilepsie
Authors:   , Hartung Nils Kristian
Published: July 2024

Polygene Risikoscores (PRS) integrieren zahlreiche Einzelnukleotid-Polymorphismen (SNP) von meist geringer Effektstärke, um Auskunft über das Erkrankungsrisiko bestimmter Krankheiten zu geben. In dieser Arbeit wurde der PRS zur genetisch generalisierten Epilepsie (GGE) von Leu et al. aus dem Jahr 2019 untersucht, um festzustellen, ob über das Erkrankungsrisiko hinaus noch Korrelationen mit weiteren phänotypischen Eigenschaften von Patienten bestehen. Der Nachweis solcher Zusammenhänge würde eine Prädiktionsfähigkeit des GGE-PRS demonstrieren, die perspektivisch ein Potential für dessen klinische Anwendbarkeit, beispielsweise im Sinne der personalisierten Medizin, aufzeigen könnte. Die Identifizierung neuer Korrelationen sollte durch Vergleich der Phänotypen von zwei Gruppen von GGE-Patienten mit extrem hohen, beziehungsweise extrem niedrigen PRS-Werten erfolgen. Hierfür wurden von 2256 Patienten aus der Datenbank von Epi25, einem internationalen Forschungskollaborativ zur Erforschung der Relevanz genetischer Faktoren bei der Entwicklung von Epilepsie, die Patienten mit den höchsten (n=59) und den niedrigsten (n=49) GGE-PRS-Werten ausgewählt. Für diese 108 Patienten wurden retrospektive klinische Daten von den jeweiligen Behandlungszentren akquiriert. Hierzu wurde den Studienleitern der Zentren ein Questionnaire mit Fragen zu zahlreichen phänotypischen Parametern der Patienten übermittelt. Die Rücklaufrate war mit 54% gut. Die so eingeholten Patientendaten wurden anschließend mittels Exaktem Test nach Fisher und Wilcoxon-Rangsummentest statistisch analysiert, um Unterschiede zwischen den Phänotypen beider Gruppen nachzuweisen. Im Falle der Pharmakoresistenz zeichneten sich hierbei zunächst signifikante Unterschiede ab, die ein selteneres Auftreten dieser Eigenschaft für Patienten mit hohen GGE-PRS-Werten implizierten. Diese Ergebnisse waren jedoch nach einer Bonferroni-Korrektur und bei Validierung in einer größeren Kohorte (n=825) nicht mehr signifikant. Für die anderen untersuchten Parameter waren ebenfalls keine signifikanten Unterschiede nachweisbar. Das Ergebnis, dass für keinen der untersuchten Parameter signifikante Differenzen bestanden, obwohl zwei Kohorten mit extrem gegensätzlichen PRS-Werten untersucht wurden, spricht gegen eine Verwendung des aktuell verfügbaren GGE-PRS als prädiktiver Biomarker über das Erkrankungsrisiko hinaus und somit gegen dessen klinische Anwendbarkeit. Jedoch können die nicht-signifikanten Korrelationen im Falle der Pharmakoresistenz als Hinweis verstanden werden, dass im Bereich der Pharmakotherapie Zusammenhänge zwischen Score und Phänotyp bestehen könnten, die weiterer Untersuchungen in zukünftigen Studien bedürfen. Bei Verwendung eines verbesserten GGE-PRS mit zusätzlichen risikoassoziierten SNP und verfeinerter Wichtung der Effektstärken sowie größerer Kohorten könnten in diesem Bereich möglicherweise auch signifikante Zusammenhänge nachweisbar werden.
INTEGRATION OF HEALTH-PRESERVING TECHNOLOGIES IN ENGLISH LANGUAGE LESSONS AT GENERAL SECONDARY EDUCATION INSTITUTIONS
Authors: Molhamova Liliia , Budko Valeriia
Published: July 2024

Modern conditions of war significantly increase the load on the psycho-emotional state of students and actualize the importance of integrating health-saving technologies into the educational process to increase the level of physical and emotional health of students, which is a key factor in their successful socialization now and self-determination in the future. The purpose of the study is to determine the theoretical and methodological foundations of the integration of health-saving technologies into the educational process in English language classes in general secondary education institutions. The study covers the analysis of psychological and pedagogical prerequisites for the formation of health-saving competence; experimental development and substantiation of health-saving techniques in the educational process. The results can be used in the pedagogical practice of teachers of various subjects to optimize the educational process. The article contributes to achieve three UN Sustainable Development Goals: health and well-being (Goal 3), quality education (Goal 4) and partnerships for sustainable development (Goal 17). The development and integration of health-saving technologies into the educational process is aimed at supporting the physical and emotional health of students, which is the key to their successful socialization and self-determination. This is in line with global efforts to improve health and well-being at all stages of life. In addition, the article emphasizes the importance of quality education that integrates health-preserving practices, making education more effective and meaningful. Ultimately, by emphasizing the importance of pedagogical experimentation and scientific research in this field, the article opens the way for partnerships and collaborations in the field of education and health care, thereby contributing to the achievement of sustainable development.
THE LEXEME "HARMONY" IN ENGLISH: DICTIONARY DEFINITIONS’ ANALYSIS
Authors: Skarlupina Yulia
Published: July 2024

The article is devoted to the semantic structure of the concept of "harmony" in English by analysing dictionary definitions based on 12 monolingual dictionaries, aiming to define the nominative lexeme “harmony”. The research resulted in distinguishing the core seme, median part and periphery of the concept, their dominance or peripherality of the semes being analysed according to the frequency of their appearance in the dictionaries. The etymology of the concept of “harmony” is also outlined in the article starting with the Greek word “harmonia” (where it is believed to be a derivative from an Indo-European verb root -ar-), the first appearance of the concept in the Middle English and to its usage in the modern language. Consequently, the development of this concept as an open dynamic system is demonstrated according to the process of its evolution from the core seme having totally physical meaning to the peripheral ones, the meanings of which are rather metaphorical. Besides, the impact of outside circumstances is considered one of the reasons for the fact that not all the features of this concept are fully verbalised in the language. As follows, the conclusion is made about the permanent development of the concept as a system. This corresponds to the general theory of a concept’s development which extends from the sensory-visual image that constitutes the core of the concept, through the gradual layering of "basic layers, where the features are arranged in progressively more abstract ways.
OCCASIONALISMS IN THE DYSTOPIAN GENRE: THE TRANSLATION ASPECT
Authors: Stepanov Vitalii , Shamrai Nadiia
Published: July 2024

The article reflects the dystopian genre as a relevant way of comprehending the past, present, and future reality in the context of socially resonant events and political cataclysms. The status of dystopian works within contemporary literature is determined. Occasionalisms in dystopias are discussed – new words generated by the author that are used in the discourse without current fixation in language dictionaries. The authors describe the role of occasionalisms in writing a dystopian book, including their potential to produce a communicative effect on the target audience. As a pilot experiment, the authors consider George Orwell’s work “1984” as an example of a classic dystopia with a solid inventory of occasionalisms that play a significant role in impressing and persuading readers. Along with the source text, two Ukrainian translations by Vitalii Danmer (2013) and Viktor Shovkun (2015) are compared. The books are contrasted in terms of their foreign cultural adaptability, i.e., how well the translators have conveyed the idea that the author of the original work wanted to produce for readers. The main attention is paid to occasionalisms. The meanings of specific occasionalisms are identified with the author’s connotation inherent in them. Translation and word-formation techniques that can reproduce a given meaning are identified: calquing, abbreviation, derivation, compounding, etc. Finally, the results are summarized. A conclusion is made which of the authors is better at rendering occasionalisms and to what extent their skills ensure the translation adequacy of the dystopian work.
WEBSITES OF ENGLISH-LANGUAGE NONFICTION PUBLICATIONS AS MULTIMODAL TEXTS: LINGUISTIC AND TRANSLATIONAL ASPECTS
Authors: Ushchapovska Iryna , Chornobuk Karyna
Published: July 2024

This article explores the phenomenon of multimodality on the example of English-language media. Headings and thematic content of sites, technical design, translation of news headlines from English to Ukrainian and vice versa were monitored.
COMPARATIVE ANALYSIS OF TURKISH AND UKRAINIAN PHRASEOLOGICAL UNITS REPRESENTING THE CONCEPT «GOD»
Authors: Kerdivar Natalia , Turdarova Nadia
Published: July 2024

The article analyzes phraseological units in Ukrainian and Turkish that nominate the concept "God," and considers the structural organization of semantic microfields in different language systems, which is fundamental for performing adequate translations. It has been discovered that for speakers from Muslim linguistic cultures, perceiving God as an absolute category is the basis of their worldview. In contrast, the Ukrainian linguistic worldview captures both a respectful and an ironic-sarcastic attitude, therefore phraseological units with this stylistic coloring cannot have equivalents in translation. This also applies to phraseological expressions that include, besides the lexeme "God," names of clerical ranks. Four main categories of core lexemes have been identified: state, relationship, activity, and characteristics. Within the phraseological semantic field of "state," the following semantic microfields are analyzed and described: wish, oath, surprise, curse, irritation. The phraseological units representing these are performative and, accordingly, have equivalents in Ukrainian. Overall, most Turkish phraseological units cannot be substituted with their Ukrainian equivalents containing the component "God" due to differences in the cultural and religious specifics of each ethnic group. Therefore, all units of Turkish phraseology can be divided into three groups. The first group includes stable expressions similar in meaning and communicative purpose. The second group consists of phraseological units without a complete equivalent in Ukrainian that include the component "God". The third group comprises linguistic units without equivalents in the target language.
TRANSLATION STRATEGIES EVOLUTION: ANALYSIS OF HISTORICAL AND MODERN TRANSLATIONS OF NOVEL TITLES OF BRITISH ENGLISH LITERATURE
Authors: Shumenko Olha , Koval Hlafira
Published: July 2024

The peculiarities of translating titles of British novels are an extremely interesting area of research for linguists, given the influence of British literature and its importance for the formation and development of world culture. It is important to analyze the translation of book titles, because they create the first impression on the reader and play a decisive role in whether he or she will be interested in the book or not. The article is devoted to the study of strategies and methods of translating titles of novels in English-language British literature. In the work, we found that when translating titles, linguists use such translation transformations as literal translation, transliteration, addition, deletion, simplification, title replacement, specification, and generalization. We analyzed the evolution of translation strategies, namely the cultural context, marketing and publishing strategies, historical context, and personal style of the translator, which have a significant impact on translation decisions. We also defined the term “title” as the first sign of the text, which gives the reader an idea of the book, and also has the greatest impact on the initial understanding of the text and becomes the first step towards its interpretation. In addition, we found out that the main difficulties in translating titles of British novels are that the translator is faced with the fact that he or she has to convey the idea of the original English-language title, take into account the cultural environment, and also interest the reader at the same time. In the context of translating British titles, it is also worth noting that the translator often has to reflect the author's style or wordplay, and for this he or she needs to have background knowledge in many fields, experience, and the ability to choose a Ukrainian equivalent to convey the essence of the book to the reader in the way the author would have wanted it to be done.
Control method for the ship track and speed in curved channels
Authors: Yanru He ,   School of Marine Engineering, Dalian Maritime University, Dalian 116026, China, Xingya Zhao , Liwen Huang , Luping Xu , Jinlai Liu ,   School of Navigation, Wuhan University of Technology, Wuhan 430063, China
Published: July 2024

Due to natural and external influences in curved channels, ships frequently require adjustments in course and speed, posing challenges for existing control methods. Particularly lacking are speed control methods suitable for curved channel navigation. This study initially developed a three-degree-of-freedom MMG model incorporating external interference. It introduced an OP-PID heading controller merging optimal control strategies with traditional PID, adaptable to both external conditions and ship speed, validated through heading control simulations. The study analysed the ship's speed change process, deriving a mathematical expression for advance distance, and proposed a dichotomy-based speed control method to determine speed change points, addressing differential equations with unknown integrands. To mitigate uncertainty errors like parameter inaccuracies in ship maneuvering models and dynamic environmental disturbances, the study proposed a comprehensive control approach. This approach integrates model predictive control, feedback compensation, segment identification, and an enhanced line-of-sight (LOS) guidance method alongside the OP-PID course controller and dichotomy-based speed control. Simulation experiments in the Dongboliao Channel compared the proposed and existing methods. Results demonstrate the proposed method's capability to handle frequent course and speed adjustments effectively, even under model errors and external interference, showcasing superior track deviation and course control accuracy over existing methods.
Analysing the Effects of Atmospheric Teleconnections on Streamflow Regime in the Eastern Black Sea Basin in Türkiye
Authors: Sezen Cenk
Published: July 2024

Analysing the variations in hydrological cycle components is essential for water resources planning and management. In this study, the relationship between the streamflow data belonging to five discharge gauging stations in the Eastern Black Sea Basin in Türkiye and the Arctic Oscillation (AO), East Atlantic-Western Russia (EAWR), North Atlantic Oscillation (NAO) and North Sea Caspian Pattern (NCP) was investigated. For this purpose, Spearman’s correlation test, ensemble empirical mode decomposition (EEMD) and relative importance analysis were used. Accordingly, Spearman’s correlation coefficients were calculated between raw streamflow data, decomposed streamflow data via EEMD and atmospheric teleconnections. Then, the relative importance analysis was applied to determine the atmospheric teleconnections’ influences on streamflow data. The findings showed that the relationship between raw streamflow data and atmospheric teleconnections is generally more significant and negative in the winter and spring. Furthermore, it was observed that the linkage between the decomposed streamflow data and atmospheric teleconnections could differentiate. Although no significant correlation between atmospheric teleconnections and raw streamflow data was detected in some months, significant correlations were detected between atmospheric teleconnections and decomposed streamflow data. This reveals the importance of examining the relationship between atmospheric teleconnections and streamflow data for different periods. The relative importance analysis revealed that the influence of atmospheric teleconnections on streamflow data could change from station to station and from component to component. This study showed that investigating the effects of atmospheric teleconnections on streamflow data for different components and periods is important.
Stress correlations in near-crystalline packings
Authors: Maharana Roshan , Ramola Kabir
Published: July 2024

We derive exact results for stress correlations in near-crystalline systems in two and three dimensions. We study energy minimized configurations of particles interacting through Harmonic as well as Lennard-Jones potentials, for varying degrees of microscopic disorder and quenched forces on grains. Our findings demonstrate that the macroscopic elastic properties of such near-crystalline packings remain unchanged within a certain disorder threshold, yet they can be influenced by various factors, including packing density, pressure, and the strength of inter-particle interactions. We show that the stress correlations in such systems display anisotropic behavior at large lengthscales and are significantly influenced by the pre-stress of the system. The anisotropic nature of these correlations remains unaffected as we increase the strength of the disorder. Additionally, we derive the large lengthscale behavior for the change in the local stress components that shows a 1/r^d1/rd radial decay for the case of particle size disorder and a 1/r^{d-1}1/rd−1 behavior for quenched forces introduced into a crystalline network. Finally, we verify our theoretical results numerically using energy-minimised static particle configurations.
GESTIÓN DEL TALENTO HUMANO Y SU INCIDENCIA EN EL CUMPLIMIENTO DE LOS OBJETIVOS DEL GOBIERNO AUTÓNOMO DESCENTRALIZADO DEL CANTÓN MONTECRISTI
Authors: Holguín López Jessica Jamilet , Macías Loor Félix Ignacio
Published: July 2024

La gestión del talento humano es un factor determinante en el cumplimiento de los objetivos institucionales del Gobierno Autónomo Descentralizado del Cantón Montecristi. Esta investigación analiza la incidencia de dicha gestión en el desempeño organizacional, partiendo de la problemática de una administración ineficiente del personal que afecta la eficacia y efectividad de los servicios públicos. El objetivo principal fue analizar la incidencia de la gestión del talento humano en el cumplimiento de los objetivos. Metodológicamente, se emplearon métodos inductivo, deductivo y bibliográfico, además de la entrevista realizada a la jefa del departamento de talento humano. Los resultados revelan que la implementación de prácticas avanzadas de gestión del talento humano, como la capacitación continua y la evaluación del desempeño, mejora significativamente el rendimiento organizacional. En conclusión, la gestión efectiva del talento humano, respaldada por indicadores claros y una evaluación continua, es fundamental para el logro de los objetivos institucionales.
Comprehensive economic losses assessment of storm surge disasters using open data: a case study of Zhoushan, China
Authors: Chen Bairu , He Zhiguo , Li Li , Chen Qian , He Junyu , Li Feixiang , Chu Dongdong , Cao Zeng , Yang Xuchao
Published: July 2024

As climate change continues to worsen, coastal areas are increasingly vulnerable to more frequent and severe storm surges. This poses a significant risk to economic entities, particularly in areas that have undergone rapid development. However, quantitative assessment of economic losses from storm surge disasters in China has been challenging due to limited exposure and vulnerability data. This study proposes a framework for comprehensive economic losses assessment of storm surge disasters using open data, focusing on Zhoushan City as an example. The study quantifies economic loss ratios caused by storm surges by identifying essential urban land use/cover (EULUC) and considering the water depth of different EULUC types for quantitative vulnerability assessment. The study then calculates direct economic losses using the loss ratio maps and gridded gross domestic product data and quantifies indirect economic losses (IEL) using an input–output model to account for inter-industry correlation. Results show that under the scenario of a super typhoon intensity (915 hPa), the total economic loss can reach 131 million CNY, with IEL accounting for 60% of the total. The construction and industrial sectors experience higher IEL due to excessive dependence on upstream and downstream industries, with IEL accounting for approximately 70%.
Biodegradability index (BDI) as an indicator for effluents quality measurement: A case study based on different industry sectors in Matara District, Sri Lanka
Authors: Diwyanjalee G. R. , Bellanthudawa B. K. A. , De Silva D. K. N. S. , Gunawardena A. R.
Published: July 2024

This study addresses the crucial need for appropriate indicators to characterize aquatic pollution, given the challenges posed by unrestricted effluent discharge globally. Focusing on wastewater from hotel and tourism industries and vehicle service stations in Matara District, Sri Lanka, we explored the relationship between biological oxygen demand (BOD) and chemical oxygen demand (COD) through the biodegradability index (BDI). Monthly water samples were collected from January 2019 to December 2022, analyzed using standard methods, and statistically evaluated. Results revealed a significant spatial variation in BDI among industry sites, with a modest temporal change. The BOD:COD ratio exhibited a slight increasing trend over time, suggesting factors beyond temporal influence. BDI correlated significantly with temperature, alkalinity, and total suspended solids (TSS), emphasizing its potential as an indicator. The study underscores the importance of complementing the BOD:COD ratio with other indicators for a comprehensive assessment of industrial effluent quality. This research contributes valuable insights into understanding wastewater characteristics, facilitating informed pollution reduction and control strategies in aquatic systems.