bluuebunny/crossref_metadata_2025 huggingface dataset:
Criticism of modern approaches to the interpretation of the concept of "threat": a detailed overview of the shortcomings of the author's ideas
Authors: Massunov Sergei L'vovich
Published: January 2025

Such a new scientific field as the theory of security, which is currently being developed, is based on a number of original concepts, including threat, challenge, risk, danger, and safety. How-ever, their content in various publications is far from unambiguously determined. In the presented work, as a result of the analysis of a wide list of existing scientific papers, a number of significant disadvantages of the interpretations of one of the cornerstone concepts of security theory, threats, proposed by various authors, are shown. The shortcomings of existing approaches to the definition of the considered product were iden-tified on the basis of the application of several methodological provisions, including methods of comparative analysis, laws of logic and requirements of terminology. As a result of the analysis carried out in the work, it is shown that among the main misconcep-tions when interpreting a threat are: – identification with danger, – representation as a set of conditions and factors that create danger, – as well as definition as a some situation (state), phenomenon, process or factor that can cause negative changes anywhere. In contrast to the presented approaches, it is emphasized that everything that can cause possible negative consequences should be considered not the threat itself, but its source. Attention is drawn to the fact that the authors of only two works adhere to the most reliable interpretation of the threat as the possibility of harm as a result of the object's influence on someone/something. In addition, some articles provide incomplete formulations of the threat, taking into account only one of its components - real or potential, which from the point of view of methodological principles should also be considered unacceptable.
Shaping Perceptions: Media Framing and Tone in reporting Kerala's Landslides
Authors: Mohammed Hashim S.
Published: January 2025

This study investigates the impact of media narratives on disaster risk and response in Kerala, India, focusing on landslides from 2018 to 2022. Through a comprehensive content analysis of three national and three regional newspapers, we examined how print media framed and portrayed significant landslides. Our findings reveal a predominant use of negative tones, emphasizing the severity and adverse impacts of these events. The most utilized frame was the responsibility frame, highlighting Governmental and NGO roles in managing disasters. Economic consequences and human-interest frames also received significant attention, reflecting the broader impacts on the economy and personal stories of affected individuals. Notably, the morality frame was absent, indicating a lack of moral and ethical discussions in the media coverage.

This study underscores the media's critical role in shaping public perception and influencing disaster management policies. By highlighting the biases and framing choices in media coverage, we provide valuable insights for media practitioners, policymakers and researchers to enhance disaster communication strategies, fostering resilience and improving disaster preparedness and response in vulnerable regions.
Methylurea-Regulated Low-Concentration (2.6m) Electrolytes for High-Voltage Aqueous Lithium-Ion Pouch Cells Using NbO2 Anodes
Authors: Hou Chuanyu , Ke Changming , Chen Runze , Lin Yangfan , Huang Qin , Wang Jianhui
Published: January 2025

Niobium-based oxides exhibit a specific capacity exceeding 300 mAh/g at operating potentials of 1.0–2.0 V vs. Li⁺/Li, significantly outperforming titanium-based oxides. Fully harnessing this high capacity has the potential to significantly enhance the energy density of aqueous lithium-ion batteries. However, the narrow electrochemical stability window of conventional aqueous electrolytes often results in severe hydrogen evolution reactions at low potentials, rendering them incompatible with the reversible lithium intercalation and de-intercalation processes required for high-capacity niobium-based oxides. In contrast to conventional strategies that rely on highly concentrated electrolytes, this study focuses on optimizing the aqueous electrolyte structure by incorporating nonflammable, low-toxicity, and cost-effective methylurea (MU) while maintaining a fixed LiTFSI/H₂O molar ratio. This approach reduces the salt concentration, viscosity, and density of the electrolyte, while simultaneously enhancing ionic conductivity and widening the electrochemical stability window. Leveraging the donor-acceptor amphiphilicity and structural asymmetry of MU, this additive demonstrates high miscibility with LiTFSI/H₂O solution. MU interacts with water, Li⁺, and TFSI⁻ to disrupt the hydrogen-bond network, forming a solvation sheath dominated by MU and TFSI⁻ coordination. This novel solvation structure renders the formation of a stable, dual-layer solid electrolyte interphase (SEI) comprising an outer organic-rich and inner inorganic-rich configuration. As a result, the cathodic stability limit extends to 1.2 V vs. Li⁺/Li, enabling compatibility with high-capacity NbO₂ anode even at a low electrolyte concentration of 2.6 m. Under stringent testing conditions, including an areal capacity of 1.3 mAh/cm², P/N ratio of 1.2, a charge rate of 0.25 C, and the use of conventional aluminum current collector, NbO₂ | LiCoO₂ (184 Wh/kg) and NbO₂ | LiMn₂O₄ (161 Wh/kg) pouch cells demonstrated stable cycling over 150 cycles with an average coulombic efficiency >99.8% and 96% capacity retention after 24 hours’ storage at 100% state of charge (SoC). This straightforward and effective approach significantly enhances the energy density of aqueous lithium-ion batteries while preserving the benefits of low cost, non-flammability, and low toxicity, thereby advancing the practical development of high-voltage aqueous batteries.
Single atom substitutions in backbone aromatic groups alter membrane permeability and biological activity of cyclic peptides
Authors: Openy Joseph , Vega-Ces Sabela , Amrahova Gulshan , Mestdach Emeline , Chi Celestine , Kissel Benjamin , 't Hart Peter
Published: January 2025

Cyclic peptides hold significant potential as disruptors of challenging targets such as protein-protein interactions, but their poor membrane permeability often limits their use for intracellular targets. Inspired by nature, we explored the introduction of aromatic groups in the peptide backbone to address this limitation. Starting from model peptide Sanguinamide A, we synthesized a series of analogues in which the native thiazole moiety was replaced with various simple aromatic groups. This approach allowed us to systematically investigate how minimal changes in the nature of the aromatic group and the flexibility of the peptide backbone influence membrane permeability. Significant differences in permeability were observed among the analogues, and for those that were permeable, NMR spectroscopy revealed conformational changes in response to environment polarity. In addition to studying permeability, we assessed the impact of these chemical modifications on biological activity using a target-agnostic cell painting assay. While permeability generally correlated with biological activity, distinct differences in activity were observed depending on the specific aromatic group incorporated. These findings highlight the importance of backbone-embedded aromatic groups in modulating both membrane permeability and biological activity, offering valuable insights for the development of cyclic peptides as therapeutic agents.
Comparative Analysis of Nextcloud and Owncloud Performance as Infrastructure as a Service (IaaS) Based Cloud Storage
Authors: Haryani Prita , Ariyana Renna Yanwastika , Majid Iqbal Abdul , Susanto Fx. Guntur Putra
Published: January 2025

Physical data storage using flash drives or local computer storage continues to be used for document archiving in database laboratories. Archived documents include laboratory inventory modules, practical course modules, practitioners' attendance cards, and students' task and response files. Utilizing cloud storage has emerged as a solution to these issues, enabling data to be easily accessed from anywhere via an internet connection. Numerous cloud storage applications now feature advanced functionalities; however, each cloud storage company varies regarding access speed, storage capacity, security, and costs. This study aims to analyze the performance of two cloud storage applications, Nextcloud and Owncloud, using throughput as a parameter. Test results demonstrated that Nextcloud's performance in file upload throughput was higher at 1065 bps compared to Owncloud's 850 bps. Similarly, in file download throughput, Nextcloud exceeded Owncloud's throughput of 2960 bps against 2564 bps. These results indicate that Nextcloud's performance surpasses Owncloud's in both file upload and download operations
Biomídia: Uma análise do uso da série Unidade Básica no Ensino Médico
Authors: Zanelatto Giovanna , Ben-Hur De Melo Fernando , Stefanello Sabrina , Vianna Dantas dos Santos Deivisson
Published: January 2025

Introdução: A presente pesquisa busca realizar uma análise qualitativa sobre a aplicação do gênero televisivo drama médico no ensino. Objetivo: Analisar o uso da série "Unidade Básica" como ferramenta pedagógica no campo da saúde coletiva. Métodos: Este estudo  utiliza metodologia de entrevista semiestruturada. Os participantes foram estudantes e professores de um curso de medicina de uma universidade pública brasileira, que vivenciaram a série televisiva “Unidade Básica” no contexto de uma disciplina do primeiro semestre do curso. Resultados: Segundo a percepção dos entrevistados, a série propiciou ampliação do olhar para a Atenção Básica, trazendo reflexões a respeito dos modelos de saúde e das representações criadas pela mídia através do drama médico. Percebe-se uma aproximação da série Unidade Básica com o modelo de medicina centrada na pessoa, e sua função pedagógica ao propiciar o contato dos estudantes com esse modelo. Conclusão: A série se apresenta como uma ferramenta didática que torna possível desenvolver discussões e abordagens sobre a Atenção Primária à Saúde em sala de aula, trazendo novas percepções e aprendizados a docentes e discentes
Perspectivas de pais de crianças menores de dois anos sobre imunização: confiança nas vacinas, fontes de informação e ações na Estratégia Saúde da Família
Authors: Dal Prá Katia Cristina , Lemos Patrícia de Lima , Pimentel Caio Lázaro Tosta , Goulart Letícia Silveira
Published: January 2025

Introdução: Apesar dos inegáveis benefícios da imunização para a saúde das crianças, alguns pais ou responsáveis mostram-se receosos diante da prática da vacinação. Objetivo: Descrever como os pais percebem a vacinação infantil e as ações realizadas na Estratégia Saúde da Família (ESF). Métodos: Trata-se de um estudo transversal com 335 pais ou responsáveis de crianças menores de dois anos cadastradas na ESF, no município de Sorriso, em Mato Grosso (MT). Os dados foram coletados por meio de um questionário estruturado. Resultados: A maioria dos entrevistados considera as vacinas seguras (82,7%) e importantes (94,3%). As fontes de informação mais citadas foram os profissionais de saúde (88,6%) e a internet (38,5%). As principais ações de incentivo à vacinação mais lembradas foram as orientações promovidas pelos Agentes Comunitários de Saúde (ACS) (75,2%) e as campanhas de vacinação aos sábados (71,9%). Conclusões: A amostra revelou que os pais consideram as vacinas importantes e seguras e que os profissionais da equipe da ESF contribuem para a informação sobre imunização. Os resultados indicam a importância da realização de campanhas de vacinação, sendo essencial que sejam ampliadas estratégias que busquem promover a adesão à imunização infantil. Este texto é fruto do programa de pós-graduação stricto sensu Mestrado Profissional em Saúde da Família (PROFSAÚDE).
Palavras-chave: Imunização; Criança; Estratégia Saúde da Família.
Don Pedrote: Un capitán indígena rebelde en territorio misional jesuita al norte de la Nueva España (1673-1692
Authors: Sánchez Luna Gilberto Sebastián , Carrillo Valdez Celso
Published: January 2025

Este trabajo analiza las causas de las rebeliones dirigidas por el capitán indígena Don Pedrote, busca rescatar del pasado parte de su vida con el propósito de comprender la forma en que se relacionó con los españoles y porqué éstos buscaron aniquilarlo, al igual que a otros capitanes indígenas que ordenaron a sus seguidores asaltar los caminos y asentamientos hispanos. Este trabajo es un estudio de tipo cualitativo que se basa en los manuscritos redactados por los conquistadores donde se hace referencia a sus actividades. Son documentos que corresponden al periodo de 1673 a 1692 y fueron elaborados con fines muy diversos: guerra contra los indios, impartición de justicia, órdenes militares, poblamiento y registro de sacramentos. El análisis se complementa con otras fuentes primarias y secundarias de tipo cualitativo. El estudio destaca que la presencia española acentúo la disputa ancestral existente entre los nómadas por el territorio donde obtenían su subsistencia y los clasificó en indios amigos o enemigos, según su sumisión forzosa o aparente al rey y a Dios y pone en evidencia la importancia de la participación como tropas de indios auxiliares para la ocupación del territorio por los españoles y la lucha contra los indios insumisos.
THE IMPACT OF GLOBALIZATION ON ENGLISH LANGUAGE PEDAGOGY IN INDIA
Authors: Chandan
Published: January 2025

Globalization has transformed the educational landscape in India, significantly influencing English language teaching and learning. With the advent of economic liberalization in the 1990s and the surge in digital technology, the demand for English proficiency has skyrocketed, shaping pedagogical methodologies. This paper explores the dual impacts of globalization on English education, analysing its role in bridging and exacerbating the urban-rural divide. Specific attention is given to government initiatives such as the New Education Policy (NEP) 2020, which aims to modernize language education while ensuring inclusivity. This study employs a mixed-methods approach to assess the evolving trends in English language pedagogy, identifying key challenges and opportunities within diverse socio-economic contexts. It concludes with recommendations to enhance English education as a tool for empowerment in a globalized world.
THE PRINCIPALS' CHALLENGES: ENSURING SMOOTH NEP 2020 IMPLEMENTATION IN ASSAM
Authors: Bharali Amarjyoti
Published: January 2025

This paper examines the challenges and opportunities associated with implementing the National Education Policy (NEP) 2020 in Assam, emphasizing its impact on higher education, particularly undergraduate colleges. It explores the role of college principals as key leaders in facilitating this transition. The study delves into Assam’s higher education landscape, highlighting issues of inclusivity, infrastructure, and resource constraints while discussing government initiatives to support policy implementation. Special attention is given to curriculum reforms, the Four Year Undergraduate Course (FYUGC), technology integration, and faculty training, all essential components of NEP 2020. By presenting successful case studies from Assam’s colleges and offering actionable recommendations for leadership development and collaborative approaches, this paper aims to guide higher education institutions toward effective implementation and long-term educational transformation.
Potential of the Agricultural Sector Based on Classification and Its Role in Sustainable Development in OKU Regency
Authors: Nurjanah Nurjanah , Munajat  , Oktarina Yetty
Published: January 2025

The agricultural sector is essential for national development, especially in managing and using key resources, emphasizing food commodities. This sector is essential for economic growth, as a significant portion of the Indonesian population depends on agriculture for sustenance. This study analyzes data from three primary sectors: agriculture, forestry, and plantations, explicitly concentrating on OKU Regency in South Sumatra Province. The assessment utilizes Location Quotient (LQ), Dynamic Location Quotient (DLQ), and Klassen Typology methodologies to analyze the viability and sustainability of specific sectors.The findings indicate that the agriculture, forestry, and fisheries sectors are fundamental and prospective contributors to the Gross Regional Domestic Product (GRDP) in OKU Regency, with a Location Quotient (LQ) value of 2.41, signifying these industries sufficiently satisfy local demand from 2014 to 2023. A comparison of LQ (2.41) and DLQ (2.81) further substantiates that these sectors are predominant and will persist as fundamental sectors in the future, indicating their sustainability. Furthermore, the Klassen Typology analysis reveals that OKU Regency exhibits a growth pattern in which the regional growth rate (r_ik) surpasses the overall sector growth rate (r_i). However, the contribution to GRDP (Y_ik) remains below the average (Y_i). This study emphasizes the agriculture, forestry, and fisheries sectors as pivotal catalysts for regional development and significant contributions to the Sustainable Development Goals (SDGs), especially in promoting sustainable economic growth, environmental conservation, and food security.
Contribution to Sustainable Development Goals (SDGs):SDG 1: No PovertySDG 2: Zero HungerSDG 6: Clean Water and SanitationSDG 11: Sustainable Cities and CommunitiesSDG 13: Climate ActionSDG 15: Life on Land
From Tokyo to Manila: The adaptation of halal Japan application system in promoting halal awareness in the Philippines
Authors: Cahyadi Eko Ruddy , Azahra Revina Novri , Fabian Haikal , Latisya Putri
Published: January 2025

The adaptation of the Halal Japan Application System is able to serve as a model to promote halal awareness in the Philippines. This is because the country has a Muslim minority and significant potential for the growth of the halal industry. The concept of Halal, derived from Islamic teachings, covers more than dietary restrictions by influencing lifestyle choices and consumer behavior across diverse sectors, including food, cosmetics, and tourism. Therefore, this research aimed to discuss the challenges and opportunities within the halal certification landscape in both Japan and the Philippines. The trend is associated with the persistence of issues such as the lack of a centralized regulatory body and varying standards among certifying agencies in Japan despite the advancements in halal certification since 2010 and the development of the Halal Japan app. Meanwhile, the Philippines faces infrastructural and awareness challenges in its burgeoning halal sector. The implementation of a similar halal app could bridge these gaps, enhancing accessibility and reliability for local and international Muslim communities. This comparison showed the need to improve the certification processes and community engagement strategies to establish the Philippines as a key player in the global halal market in order to foster economic growth and cultural integration.
SISKEUDES dan Akuntabilitas Keuangan Desa: Persfektif Keuangan Islam
Authors: Salman Yuhasma
Published: January 2025

Abstrak. Direktorat Jenderal Pemerintahan Desa Kementerian Dalam Negeri (Ditjen Bina Pemdes) bekerja sama dengan Badan Pengawasan Keuangan dan Pembangunan (BPKP) mengembangkan Aplikasi Sistem Keuangan Desa (SISKEUDES) yang dirancang untuk meningkatkan pengelolaan sistem keuangan desa. Melalui studi kasus di Nagari Indudur, Kecamatan IX Koto Sungai Lasi, Kabupaten Solok, penelitian ini bertujuan untuk mengevaluasi peran dan fungsi aplikasi SISKEUDES dalam pengelolaan anggaran desa serta implikasinya yang lebih luas terhadap akuntabilitas keuangan di masyarakat. Penelitian ini menggunakan metodologi penelitian kualitatif untuk menggali lebih dalam dan memberikan pemahaman yang komprehensif tentang masalah yang diteliti. Hasil studi kasus dari penelitian ini menandakan SISKEUDES membantu perangkat desa dalam menciptakan akuntabilitas keungan yang Islami. Penggunaan aplikasi ini memungkinkan pelaporan yang tepat waktu dan transparan, mencerminkan tanggung jawab yang sesuai dengan ajaran agama, seperti yang dijelaskan dalam QS Al-Infithaar 10-12 dan QS Al-Jaatsiyah 29. Dengan memanfaatkan aplikasi SISKEUDES, staf administrasi Nagari Indudur dapat menghasilkan laporan keuangan yang tepat waktu dan akurat sekaligus menumbuhkan kepercayaan publik terhadap pengelolaan dana desa, memastikan dana desa digunakan secara teratur dan bertanggung jawab setiap tahun. 
Abstract. The Directorate General of Village Governance under the Ministry of Home Affairs (Ditjen Bina Pemdes) collaborated with the Financial and Development Supervisory Agency (BPKP) to develop the Village Financial System Application (SISKEUDES), designed to enhance the management of village financial systems. and the Directorate General of Village Administration (Ditjen Bina Pemdes) of the Ministry of Home Affairs. Home Affairs. This paper aims to determine the role of the SISKEUDES application in village finance and its effect on village accountability. application in village finance and its influence on village financial accountability through a case study in Nagari Indudari. through a case study in Nagari Indudur Kec. IX Koto Sungai Lasi, Kab. Solok. This research focuses on examining the role of SISKEUDES in advancing transparency and accountability within the framework of village financial governance. The case study results of this research show that SISKEUDES helps village officials in creating Islamic financial accountability. The use of of this application allows for timely and transparent reporting, reflecting responsibility in accordance with religious teachings, as described in QS Al-Infitha As described in QS Al-Infithaar 10-12 and QS Al-Jaatsiyah 29. SISKEUDES, the Indudur Nagari Wali apparatus can manage and report on the the use of village funds systematically and accountable every year, produce relevant and timely financial reports, and increase public trust. and on time, and increase public trust in financial management finances.
Doenças Testiculares
Authors: Andrade Eduardo Henrique Ferreira , Doneiro Luiz Gustavo Avelar , Kashiwabara Tatiliana Geralda Bacelar
Published: January 2025

A criptorquidia é uma condição caracterizada pela falha de um ou ambos os testículos em descer para o escroto antes do nascimento. Normalmente, os testículos se desenvolvem dentro do abdômen do feto e descem gradualmente para o escroto durante o desenvolvimento fetal. Quando isso não acontece, o testículo é considerado criptorquídico.
Dispneia
Authors: Botelho Bárbara Gonçalves , Castro Bruna Lima , Kashiwabara Tatiliana Geralda Bacelar
Published: January 2025

Dispneia é a experiência subjetiva de respiração difícil, trabalhosa ou desagradável. A sensação de dispneia frequentemente é mal ou vagamente descrita pelo paciente. A dispneia é geralmente considerada aguda quando dura de horas a dias e é considerada crônica quando dura mais de 4 a 8 semanas
Tosse Crônica
Authors: Marinho Alice Vilas Boas , Figueiredo Elisa Rocha Oliveira , Kashiwabara Tatiliana Geralda Bacelar
Published: January 2025

A tosse trata-se de um artifício de expulsão forçado usado pelo organismo para proteção, ocasionado pela ativação reflexa de receptores sensoriais na mucosa das vias aéreas quando há um fator irritante. A tosse é crônica em adultos quando o período de duração é igual ou supera 8 semanas.
Desenvolvimento Neuropsicomotor
Authors: Melquíades Marco Antônio Teixeira , Portes Vinicius Machado , Kashiwabara Tatiliana Geralda Bacelar
Published: January 2025

O desenvolvimento neuropsicomotor refere-se ao processo pelo qual uma criança adquire habilidades motoras, cognitivas, emocionais e sociais desde o nascimento até a adolescência. Esse desenvolvimento é influenciado por uma interação complexa entre fatores genéticos e ambientais e é fundamental para o crescimento saudável e a capacidade da criança de interagir e adaptar-se ao seu ambiente. Os problemas no desenvolvimento neuropsicomotor são, em geral, subdiagnosticados, sendo importante o conhecimento do médico da atenção básica acerca do desenvolvimento normal de uma criança, bem como dos seus sinais de alerta vermelho, para que se possa realizar uma intervenção precoce.
Dores em Membros
Authors: Amaral Andrezza Andrade Esperança do , Lopes Nilma Ferreira , Kashiwabara Tatiliana Geralda Bacelar
Published: January 2025

A dor do crescimento é de caráter benigno com início na infância e término na vida adulta. Essa síndrome, é caracterizada por dor musculoesquelética intermitente bilateral, não inflamatória e com prevalência no período noturno.
Distributed machine learning pipelines in multi-cloud architectures: A new paradigm for data scientists
Authors: Atughara John Chukwuebuka
Published: January 2025

In this article, the author captures a comprehensive guide of the distributed MLP in the multi-cloud environment as critical to data scientists. The paper will discuss the existing machine learning pipelines and the realities and potentials of multi-cloud computing; the paper will also explain the propagation, uses, and effective enabling of efficient and scalable machine learning pipelines. The article describes the proper way of customised distribution of pipelines across clouds by using theoretical work, as well as the authors’ observations and examples of the use of distributed machine learning in multi-cloud environments. From the results, it is clear that this new approach can improve data handling, training, and deployment, which can advance the data science domain.
Adaptive machine learning in federated cloud environments: Advancing data-centric AI
Authors: Atughara John Chukwuebuka
Published: January 2025

This article examines the integration of adaptive machine learning (ML) within federated cloud environments, with a particular focus on its potential to advance data-centric AI. The study reviews the current landscape of federated learning, analyses the challenges and opportunities it presents, and evaluates adaptive ML techniques designed to enhance data privacy and model performance. Combining theoretical analysis with practical case studies, the paper offers valuable insights into the implementation of adaptive ML in federated cloud settings. The findings emphasise the significance of adaptive strategies in improving the efficiency, scalability, and security of AI models in distributed environments.
Exploring the intersectionality of gender and race in employment discrimination: Case studies from the corporate sector
Authors: Jinyoung Hwang
Published: January 2025

This study examines how intersecting identities of gender and race shape experiences of employment discrimination within the corporate sector. Drawing on intersectionality theory, the research analyzes how overlapping systems of oppression manifest in hiring, promotion, and wage practices. Case studies focus on the compounded challenges faced by women of color, such as limited access to leadership roles, wage gaps, and exclusion from informal networks. The findings highlight structural barriers perpetuating inequality, including implicit biases, tokenism, and culturally exclusive corporate cultures. Corporate diversity initiatives, often designed to address singular identity dimensions, are critiqued for their failure to tackle intersectional inequities. Document analysis and interviews with affected employees reveal the inadequacy of anti-discrimination frameworks in addressing compounded biases. Recommendations include integrating intersectionality into corporate policies, promoting transparent recruitment and promotion practices, and fostering inclusive workplace cultures. The study underscores the need for accountability measures in diversity initiatives and legislative reforms to address intersectional discrimination effectively. By advancing the understanding of systemic workplace inequities, this research provides actionable strategies for achieving equity and inclusion.
Evaluation of the interaction between the ethanol pulp extract of Chrysophyllum albidum and Artemether/ Lumefantrine
Authors: Ebubechukwu Favour Chibzoom-Pius  , Chibueze Peter Ihekwereme  , Adanna Perpetua Ikebudu  , Amara Naomi Ulasi
Published: January 2025

Objective: Though Chrysophyllum albidum has antimalarial and antioxidant property, it is commonly consumed as a fruit in the South East Nigeria. There could be possible pharmacodynamics and pharmacokinetics interaction if the fruit is consumed while on malaria treatment with artemether-lumefantrine.

The study was designed to investigate the possible enhancement of the antimalarial potency as well as possible herb-drug interaction resulting from concurrent administration of artemeter-lumefantrine and Chrysophyllum albidum.

Materials and methods: Combinations of artemeter-lumefantrine and Chrysophyllum albidum were investigated in Antiplasmodial activity using curative test procedure. Forty mice were infected with P. berghei-infected red blood cells by intraperitoneal injection. The animals (23-27g, 5-6 weeks old) were divided into 8 groups (n=5). There were treated with 250 mg/kg, 500 mg/kg and 1000 mg/kg of the extract in combination with 20 mg/120 mg of artemether-lumefantrine. The parasitemia level was determined by counting the number of parasitized erythrocytes in random fields of the microscope. The effect of Chrysophyllum albidum on the pharmacokinetics of Artemether-lumefantrine (A/L) in mice was studied in three phases. Each phase was done utilizing a total of 30 rats assigned to 5 groups of 6 animals to which was administered A/L and/or the plant extract orally, after an overnight fast, with feeding and access to water resuming 2 h after drug administration. Concentration of artemether-lumefantine was determined using modified validated liquid chromatography assay.

Results: The combination of the pulp extract and Artemether-lumefantrine at tested doses of 250, 500 and 1000 mg/kg produced significant (p< 0.05, 0.01 and 0.001), dose dependent parasitaemia suppression (88.81, 94.58 and 100%) compared to the negative control group. The plasma concentration of Chrysophyllum albidum +Artemether-lumefantrine had a concentration of (56 ng/mg) at 30 minutes. The overall systemic exposure of AL, represented by the AUC, increased by 56.05% when CAL was concurrently administered and by 296.97% when the mice were pre-treated with the decoction.

Conclusion: Chrysophyllum albidum extract has a potential to increase the antimalaria property of Artemether-lumefantrine due to probable inhibitory effect on Artemether-lumefantrine metabolism by Chrysophylum albidum. The pharmacokinetics of Artemether-lumefantrine like systemic exposure and half-life were also affected by Chrysophylum albidum.
Sustainable textile industry: Balancing growth and environmental concerns in Bangladesh
Authors: Shuvo Kumar Mallik  , Ramjan Ali  , D. M. Nahiduzzaman  , Suchayan Chakraborty Shoumik  , Torikul Islam  , M Abeedur Rahman
Published: January 2025

Over the last three decades, the textile and apparel (T&A) sector has been the primary engine of economic growth in Bangladesh. The (T&A) industry’s widening contribution led the country to sustained economic growth, reduced poverty and increase in per capita income. Thanks to its competitive edge a large pool of cheap labor, easy access to power, and a huge job creation potential the (T&A) sector has become the most thriving industry in Bangladesh to date. But the pursuit of rapid economic growth has resulted in the explosion and hasty construction of textile factories and enterprises. The growing textile enterprises, most of which are concentrated in a few places, is taking a heavy toll on the nation's human health. ecosystems, that the environment as a whole. Thus, it is essential to approach the burgeoning threat of environmental deterioration, in a sustainable manner, which achieves a balance between (T&A) industrial development and inflicts the least possible trauma on the environment and human health. That’s because the nation’s biggest money-maker and job-creator has become one of its biggest polluters. This paper will analyze the root causes behind Bangladesh’s poorly managed T and A sector and its negative impacts on environment and human health and will mention some possible solutions to improve the environmental performance of this sector and ensure its safe development.
Architecting quantum-resistant cybersecurity: A framework for transitioning to post-quantum cryptographic systems
Authors: Venkata Rajesh Krishna Adapa
Published: January 2025

The emergence of quantum computing presents a significant threat to contemporary cryptographic systems, necessitating a fundamental transformation in cybersecurity architecture. This article presents a comprehensive framework for transitioning to post-quantum cryptographic solutions, examining both theoretical foundations and practical implementation strategies. Through systematic analysis, the article evaluates leading quantum-resistant algorithms, including lattice-based cryptography, hash-based schemes, and multivariate quadratic equations, assessing their viability for enterprise-scale deployment. The article addresses critical challenges in integrating these solutions into existing infrastructure while maintaining operational continuity and security assurance. The article proposes a structured approach to organizational preparation, incorporating risk assessment methodologies, resource allocation strategies, and adaptation frameworks for legacy systems. The findings demonstrate that successful transition to quantum-resistant cryptography requires a multi-faceted approach combining technical implementation with organizational readiness. This article contributes to the growing body of knowledge on post-quantum cybersecurity by providing actionable insights for organizations preparing for the quantum computing era, while highlighting areas requiring further investigation in the evolving landscape of cryptographic security.
AI in smart cities with cellular wireless technologies: optimizing urban infrastructure
Authors: Kavita Swapnil Kulkarni
Published: January 2025

This article presents a comprehensive analysis of Artificial Intelligence (AI) integration with cellular wireless technologies in smart city environments, examining their impact on urban infrastructure optimization. Through analysis of implementations across numerous smart city initiatives in Europe and North America, the article demonstrates significant improvements in operational efficiency and resource utilization. The article reveals that edge computing implementations achieve substantial processing time reductions, while 5G networks support massive device densities per square kilometer with exceptional reliability. Traffic management systems show significant reduction in peak-hour congestion, while public safety systems achieve impressive threat detection rates. Energy management implementations demonstrate high optimization rates in distribution, and water management systems achieve excellent leak detection accuracy. The article particularly emphasizes the role of integrated AI and cellular technologies in achieving sustainable urban development, with implementations showing considerable reduction in energy consumption and decrease in carbon emissions. These findings provide valuable insights for urban planners and technology implementers, establishing benchmarks for future smart city developments.
Sustainability in transformer manufacturing: The role of renewable energy in automating coil winding machines
Authors: Abidemi Obatoyinbo Ajayi  , Ogwu Chinelo Maryjane  , Akese Emmanuel  , Chinonso Nwanevu
Published: January 2025

Sustainability in transformer manufacturing has become a critical focus as industries worldwide strive to reduce carbon footprints and adopt environmentally friendly practices. This study examines the integration of renewable energy in automating coil winding machines, a pivotal process in transformer production. The research highlights how renewable energy sources, such as solar and wind power, can drive automation, reducing dependency on non-renewable energy and minimizing greenhouse gas emissions. The study explores the technological advancements in coil winding automation, including the use of precision robotics, smart sensors, and machine learning algorithms, all powered by renewable energy systems. Automating coil winding with renewable energy not only enhances operational efficiency but also contributes to sustainable manufacturing by lowering energy costs and promoting green energy adoption. Additionally, this integration addresses challenges such as energy intermittency through hybrid renewable systems and energy storage solutions. The research underscores the importance of designing renewable energy-powered manufacturing systems to ensure scalability and resilience in production lines. This study also evaluates the economic and environmental benefits of renewable energy automation in transformer manufacturing, emphasizing the potential for cost savings and reduced environmental impact. Key findings include a 30% reduction in energy consumption and a 25% increase in production efficiency when renewable energy-driven automation is implemented. Moreover, the adoption of sustainable practices aligns with global sustainability goals and enhances the industry's competitiveness in green markets. The findings emphasize the transformative potential of renewable energy in driving automation while fostering sustainability in transformer manufacturing. Future research directions include exploring advanced energy management systems and the role of policy incentives in accelerating adoption. This study contributes to the broader discourse on sustainable industrial automation and renewable energy integration, serving as a blueprint for environmentally conscious manufacturing practices.
Performance evaluation of atmospheric water generators under suboptimal humidity conditions in Orangeburg, SC
Authors: Nasrollah Hamidi  , Patience Ferguson  , Alicia Dankwa  , Hadyn Hines
Published: January 2025

Two commercial atmospheric water generators (AWGs) were studied to compare their performance under varying environmental conditions. The efficiency of water harvesting depends on factors such as the instrument’s design, power consumption, ambient temperature, and relative humidity (RH). AWGs operate optimally at humidity levels above 80% at room temperatures but also serve as efficient dehumidifiers in high-humidity regions. To ensure high-quality drinking water, AWGs use food-grade materials for condenser coatings and employ advanced filtration systems, including reverse osmosis and UV sterilization. This study presents the water harvesting performance of these devices during the summer in Orangeburg, SC, where the average laboratory temperature ranged from 25–29 °C, and RH was between 59–69%. Results highlight the potential and limitations of AWGs in moderate-humidity environments. Under these conditions, the AWG1, harvested 1.56 mLW⁻¹, which means $0.077 per liter of water at the electricity rate of $0.12kW⁻¹. The AWG2 harvested 0.42 mLW⁻¹, or $0.29 per liter of water at the same electricity rate.
Malnutrition in Children at General Tinio, Nueva Ecija and the Assimilation of Interventions to Prevent the Condition
Authors: Reguyal June Christian G. , Gamiao Kristhine Abegail M.
Published: January 2025

Undernutrition is a complex issue that affects various aspects of life. Malnutrition increases the risk of various diseases and infections. Undernutrition can also lead to chronic health conditions such as obesity and diabetes. The study aims to determine the malnutrition among children below five years old at General Tinio, Nueva Ecija. The study analyzed a population of 3,693 children aged 0–5 years old from General Tinio, Nueva Ecija, based on data from the 2022 Nutrition Survey conducted by the Municipal Health Office. Using a total population sampling technique, the entire dataset was included to ensure comprehensive representation. Nutritional assessments were conducted following the World Health Organization (WHO) Classification of Nutritional Status of Infants and Children, with variables such as weight-for-age, height-for-age, and BMI-for- age analyzed against WHO standards. Data analysis employed descriptive statistics to determine the prevalence and severity of malnutrition (stunting, wasting, underweight, overweight, and obesity). Results were categorized, presented in tables, and compared across genders to identify disparities, with trends and risk factors interpreted in line with global and local benchmarks. Results: The overall prevalence of overweight is 6.04%, and the prevalence of obesity is 6.15%. Overall, undernutrition specifically overweight and obesity is also a concern for children aged 0-5 years old with a significant proportion of children in the overweight and obese categories. The global prevalence of obesity in children and adolescents aged 5-19 years has increased from 0.7% to 5.6% for girls and from 0.9% to 7.8% for boys from 1975 to 2016. In the United States, 1 in 5 children and adolescents are affected by childhood obesity. The American Academy of Pediatrics has issued its first comprehensive guideline on evaluating and treating children and adolescents with obesity, which reflects growing concerns about health later in life. The guideline recommends that pediatricians try to see children with obesity and provide comprehensive programs to help them manage their weight. Childhood obesity is a complex issue that can be caused by many factors, including behavior, genetics, and societal and community factors such as access to healthy food and beverages.
The Correlation Between the Type of Fluid Administration and the Incidence of Hypotension in Patients Undergoing Spinal Anesthesia at RS Wijayakusuma Purwokerto
Authors: Taufiqurrahman Sauqi , Cing Marta Tania Gabriel Ching
Published: January 2025

Background: Spinal anesthesia is a type of regional anesthesia that involves injecting a local anesthetic into the subarachnoid area. The effect of sympathetic blockade in spinal anesthesia can cause dilation of blood vessels, suppress systemic vascular resistance and result in hypotension [1]. The effects of hypotension are pulmonary aspiration, cardiac arrest, respiratory depression, and loss of consciousness. A sudden drop in blood pressure can also cause a heart attack, a complication of spinal anesthesia. Method: A quantitative approach using a correlational observational design with research variables, namely the administration of fluid types with the incidence of hypotension in patients undergoing spinal anesthesia.  The research was conducted in the IBS room at Wijayakusuma Hospital, Purwokerto, with samples was calculated obtained 53 respondents who were selected using a purposive sampling technique. The relationship between the two variables tested was carried out using the non-parametric chi square statistical test with the Fisher exact test Results: Among the respondents, the type of fluid administered was crystalloids in 98.1% of cases, with 70.2% of respondents not experiencing hypotension. The chi-square test yielded a p-value of 1.000, indicating no significant correlation between the type of fluid administered and the incidence of hypotension in patients undergoing spinal anesthesia.  Conclusion: There is no significant correlation between the administration of crystalloid or colloid fluids and the incidence of hypotension in patients undergoing spinal anesthesia at RST Wijayakusuma Purwokerto.
Level of Intention on Blood Donation Among NEUST Community: A Basis for Blood Type Repository
Authors: Reguyal June Christian G. , Baguio Hazel Mae F. , Alfonso Katherine R. , Astelero Kyla Ivy B. , Abella Aaron Miguel C. , Balcos Pamela O.
Published: January 2025

Blood is a fluid that travels to all areas of the body that pumped by the heart as well as oxygen, nutrients, and waste materials away from the cells. Therefore, the demand for human blood is high and, having a steady and varied blood supply is still challenging. Blood donation plays a crucial role in maintaining public health, guaranteeing sufficient resources.  However, recognizing the distribution of different blood types within a community is imperative for successful donation initiatives.With the help of this study, the Nueva Ecija University of Science and Technology (NEUST) community will have a comprehensive blood type database, which will serve as a basis for future blood type repository aimed at enhancing community resilience and improving the health of those in need of transfusions. It also emphasizes the significance of awareness and intention in encouraging blood donation. By addressing misconceptions and barriers, future initiatives can effectively engage the NEUST community. The result of the study showed that approximately of NEUST Community were aware of their blood type and blood donation. Furthermore, the level of their intention and knowledge demonstrated by respondents regarding their blood type and the importance of blood donation enables the researchers to establish a comprehensive blood repository. Level of Intention on Blood Donation Among NEUST Community: A Basis for Blood Type Repository serves as a vital resource for potential donors and recipients within the NEUST community, facilitating timely and efficient blood transfusion services when needed.
The Effects of Booklet Media on the Knowledge of Prospective Brides and Grooms Regarding Physical and Psychological Preparation at the KUA of Sokaraja District
Authors: Kusumawardani Alfia Putri , Linggardini Kris
Published: January 2025

Prospective brides and grooms are two individuals planning to start a life together in marriage, aiming to form a harmonious and sustainable family. They need to prepare their reproductive health, both for the bride and groom, so that after marriage, they can have a good health status to produce a quality generation. This quantitative research used a Pre-Experiment approach with One Group Pre-Test and Post-Test design. The population in this study was 492 prospective brides and grooms, with a sample of 44 respondents. Data analysis was performed using the Wilcoxon Test. Wilcoxon test results p-value of 0.00>0.05. Hypothesis (Ha) is accepted which shows the results of the study that there is a significant influence of booklet media on the knowledge of prospective brides and grooms. Booklet media. Booklet media significantly affects prospective brides and grooms' knowledge regarding physical and psychological preparation at the KUA of Sokaraja District.