bluuebunny/crossref_metadata_2025 huggingface dataset:
VIOLENCIA INTERPERSONAL CONTRA ADOLESCENTES: ANÁLISIS DE LOS CASOS NOTIFICADOS EN EL ESTADO DE ESPÍRITO SANTO
Authors: Pereira Thais França Armeláo , Santos Dherik Fraga , Luis Mayara Alves , Leite Franciéle Marabotti Costa
Published: September 2023

RESUMEN Objetivo: identificar la frecuencia de notificación de casos de violencia interpersonal contra adolescentes en Espírito Santo, Brasil, y los factores asociados. Método: estudio transversal realizado entre 2011 y 2018 con datos del Sistema de Información sobre Problemas de Salud de Notificación Obligatoria. Las asociaciones se sometieron a las pruebas chi-cuadrado de Pearson y regresión de Poisson. Resultados: la frecuencia de violencia interpersonal fue del 72,2%. El desenlace se asoció con adolescentes varones, de 10 a 12 años de edad, de raza negra/morena y sin discapacidades/trastornos; al igual que con incidentes en la vía pública y agresores del sexo masculino bajo sospecha de consumo de alcohol (p < 0,05). Conclusión: la violencia interpersonal es un problema con graves repercusiones a lo largo de la vida. Este estudio contribuye a revelar la importancia de supervisar la violencia con el fin de conocer la magnitud del daño, como también sus características para la promoción de la salud, prevención de los eventos y debida intervención.
Admisión a carreras universitarias con cursos de ingreso y cupos protegidos: reflexión desde una carrera de medicina (Río Negro, Argentina)
Authors: Bellotti Mariela , Guaresti Germán , Pozzio María
Published: September 2023

El artículo aborda la experiencia de implementación de un sistema de admisión a la nueva carrera de Medicina de la Universidad Nacional de Río Negro, Argentina, analizada desde los debates en torno a las formas de admisión e ingreso en los sistemas de educación superior. A partir de los relatos de quienes formaron parte del proceso, se describen las características del ingreso y los balances realizados. Se concluye sobre la importancia del acompañamiento docente en la implementación de cursos de ingresos con cupos.
“Narratives of Weight”: experience report of the construction of an educational course about weight stigma and health care
Authors: Oliveira Luana Cordeiro de , Soares Ariel Regina da Silva , Sabatini Fernanda , Ulian Mariana Dimitrov , Unsain Ramiro Andrés Fernandez , Scagliusi Fernanda Baeza
Published: September 2023

Weight stigma is defined as the devaluation of people due to their higher body weight, causing harmful effects to health and is present among healthcare undergraduate students and professionals. Addressing weight stigma in training spaces is crucial to fight against it. This article reports the experience about the construction of the educational course “Narratives of Weight: weight stigma and health care”, aimed at healthcare undergraduate students and professionals. Priority was given to the diversity of materials, range of perspectives, language accessibility and the presence of fat people. It is considered that the course’s building process has elements that can guide the development of other powerful and contextualized materials and interventions for the target audience.
INFLAMMATORY BOWEL DISEASE AND SARCOPENIA: A FOCUS ON MUSCLE STRENGTH - NARRATIVE REVIEW
Authors: MENDES Joana , SIMÕES Catarina D , MARTINS Joana O , SOUSA Ana S
Published: September 2023

ABSTRACT Inflammation, changes in nutrient absorption and gut dysbiosis are common conditions in patients with inflammatory bowel disease. These factors may lead to variations in macro- and micronutrients and, particularly, to an imbalance of protein metabolism, loss of muscle mass and development of sarcopenia. This narrative review aims to present the set of factors with impact in muscle strength and physical performance that may potentially mediate the relation between inflammatory bowel disease and sarcopenia. Studies that associated changes in muscle strength, sarcopenia and inflammatory bowel disease were selected through a literature search in databases Medline, Pubmed and Scielo using relevant keywords: muscle strength, physical performance, sarcopenia and inflammatory bowel disease. Chronic inflammation is currently reported as a determinant factor in the development of muscle atrophy in inflammatory bowel disease. In addition, strength decline in inflammatory bowel disease patients may be also influenced by changes in body composition and by gut dysbiosis. Measures of muscle strength and physical performance should be considered in the initial identification of sarcopenia, particularly in patients with inflammatory bowel disease, for a timely intervention can be provided. Presence of proinflammatory cytokines, high adiposity, malabsorption and consequent deficits of macro and micronutrients, loss of muscle mass, and gut dysbiosis may be the main factors with impact in muscle strength, that probably mediate the relation between inflammatory bowel disease and sarcopenia.
PRECLINICAL MODELS OF LIVER CÂNCER
Authors: GALVÃO Flávio Henrique Ferreira , TRALDI Maria Clara Camargo , ARAÚJO Renata Sandres Souza , STEFANO Jose Tadeu , D’ALBUQUERQUE Luiz Augusto Carneiro , OLIVEIRA Claudia P
Published: September 2023

ABSTRACT Background: This manuscript provides an overview of liver carcinogenesis in murine models of hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA). Objective: A review through MEDLINE and EMBASE was performed to assess articles until August 2022. Methods: Search was conducted of the entire electronic databases and the keywords used was HCC, CCA, carcinogenesis, animal models and liver. Articles exclusion was based on the lack of close relation to the subject. Carcinogenesis models of HCC include HCC induced by senescence in transgenic animals, HCC diet-induced, HCC induced by chemotoxicagents, xenograft, oncogenes, and HCC in transgenic animals inoculated with B and C virus. The models of CCA include the use of dimethylnitrosamine (DMN), diethylnitrosamine (DEN), thioacetamide (TAA), and carbon tetrachloride (CCl4). CCA murine models may also be induced by: CCA cells, genetic manipulation, Smad4, PTEN and p53 knockout, xenograft, and DEN-left median bile duct ligation. Results: In this review, we described different murine models of carcinogenesis that reproduce the key points for HCC and CCA genesis allowing a better understanding of its genetic, physiopathological, and environmental abnormalities. Conclusion: Each model has its advantages, disadvantages, similarities, and differences with the corresponding human disease and should be chosen according to the specificity of the study. Ultimately, those models can also be used for testing new anticancer therapeutic approaches.
Panorama da literatura científica brasileira sobre saúde mental na universidade: uma revisão sistemática
Authors: Araujo Alex Viana de , Vieira Fernanda David , Manfroi Edi Cristina
Published: September 2023

Resumo Com o objetivo de compreender o fenômeno saúde mental no contexto de trabalho das Instituições de Ensino Superior, esta revisão sistemática da literatura analisou as publicações nacionais no período entre 2011 e 2021. O levantamento da produção acadêmica ocorreu nos Periódicos CAPES, SciELO, Portal Regional da Biblioteca Virtual em Saúde (BVS) e Pepsic. Apenas 35 artigos atenderam aos critérios de inclusão. Os assuntos mais abordados relacionados à saúde mental dos servidores no ambiente acadêmico são: produtividade e transtornos mentais comuns, sofrimento mental/adoecimento, outros transtornos mentais, síndrome de burnout, contexto de trabalho e saúde mental. Os achados apontam para um maior número de publicações no ano de 2020, concentrados em periódicos da área da saúde, estudos empíricos, quantitativos, realizados na grande maioria em instituições públicas de ensino, preferencialmente com docentes, com predominância na região sudeste do país. Há lacunas por região, tema e categoria profissional, o que requer maiores esforços de pesquisas na área para melhor compreender o tema.
FIES, PROUNI e REUNI: caminhos inacabados para a democratização do acesso à educação superior
Authors: Moro Guilherme Andre Dal , Gisi Maria Lourdes
Published: September 2023

Resumo O estudo tem como objetivo de pesquisa investigar as políticas públicas de democratização do acesso à Educação Superior e identificar como estas políticas expansionistas se apresentam na produção científica da área de educação. Trata-se de uma pesquisa qualitativa, realizada mediante uma revisão narrativa na base de dados da Scientific Electronic Library Online - SciELO e do Portal de Periódicos Capes. Foram selecionados 58 artigos com base nas etapas e diretrizes do PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses): identificação, triagem, elegibilidade e inclusão. Os estudos deixaram evidente que as políticas públicas de Estado direcionadas à democratização do acesso à Educação Superior, ao longo das últimas duas décadas, objetivaram o aumento do número de vagas e matrículas no setor como mecanismo de promoção de inclusão social, sem alterar substancialmente os fatores que originam a desigualdade e a exclusão em questão. Resultados mais efetivos destas políticas públicas demandam melhoria da infraestrutura de Educação Básica e Superior, da formação, qualificação e remuneração dos professores, das condições de permanência dos estudantes e de maior valorização da escola e da própria universidade.
A pesquisa em educação: histórico e tendências temáticas na pós-graduação stricto sensu do Pará, Região Norte, Brasil
Authors: Pantoja Gracilene Ferreira , Ramos João Batista Santiago , Cordeiro Yvens Ely Martins
Published: September 2023

Resumo Esta pesquisa analisou as produções científicas sobre o surgimento da pesquisa em Educação na Região Norte e as tendências temáticas de três programas de pós-graduação stricto sensu das universidades públicas federal e estadual do Pará – Brasil, entre os anos de 2005 e 2021, por meio da pesquisa bibliográfica e documental. Foram analisadas um total de 820 dissertações com base na análise temática e descritiva. Como resultado, constatou-se que o surgimento da Pesquisa em Educação ocorreu após um longo percurso que culminou na militância intelectual dos líderes de grupos de pesquisas no fazer científico-acadêmico. No âmbito das pós-graduações, identificou-se elevada diversidade de temas, sendo no programa PPGED-UFPA (55), PPGED-UEPA (37) e PPEB-UFPA (22) com maior frequência absoluta na temática da Formação de Professores, Ensino de Matemática e Currículo. Ambos seguindo tendências históricas, sociopolíticas e econômicas de cada época em que foram produzidas.
Puberty and parturition on the antral follicle count of female Nelore beef cattle
Authors: Pfeifer Luiz Francisco Machado , Oliveira Júnior Jair Sábio de , Seneda Marcelo Marcondes , Camargo Higor Souza de , Morotti Fábio , Andrade Evelyn Rabelo , Moreira Elizângela Mirian , Andrade Jéssica Souza , Silva George Moreira da , Porto Marlos Oliveira , Cavali Jucilene
Published: September 2023

Abstract The objective of this work was to investigate whether puberty and parturition alter the antral follicle count (AFC) in female Nelore (Bos indicus) beef cattle. Two experiments were carried out to compare AFC between the prepubertal and pubertal periods and between the prepubertal and postpartum periods. AFC and follicle concentrations did not differ between the prepubertal and pubertal periods. However, the ovarian area increased after puberty. In addition, AFC and the ovarian area were greater in the postpartum than in the prepubertal period. Therefore, AFC is not affected by the puberty of Nelore heifers, but increases significantly when the prepubertal heifers become cows.
The influence of latitude and sky conditions on daylight harvesting inbuildings
Authors: Fonseca Raphaela Walger da , Pereira Fernando Oscar Ruttkay , Queiroz Elaine Aparecida , Stockhausenn Beatriz
Published: September 2023

Abstract The potential of daylight harvesting is related to the building location. However, climatic zonings adopted by energy efficiency programs focus only on the thermal performance, neglecting important variables of the buildings’ luminous performance. This paper aims to investigate the relationship between the angle of solar incidence, the annual occurrence of clear sky, and the annual lighting energy consumption when daylight harvesting is practiced. The lighting consumption of a square floor space, orientated in the cardinal directions, was simulated for 20 Brazilian cities. The frequency of the 15 CIE sky types was determined for each city using weather files and the angle of solar incidence was calculated for each hour of the year. The analysis comprised graphical exploration, Pearson's correlation, and multiple regression. The sensitivity of the consumption to the other two variables could be perceived in the hourly but not the annual analysis. The correlation between annual consumption and latitude was more robust for the intertropical range, with increased consumption moving south, and varied significantly for each orientation. It was concluded that, although relevant, the variables are not representative of variations in annual lighting consumption for application in climate zoning.
Análise do potencial de uso do fíler basáltico como substituição parcial do cimento Portland
Authors: Meinhart Alice Helena , Macedo Rodrigo Brunetti , Guterres Tayná Thomaz , Arnold Daiana Cristina Metz
Published: September 2023

Resumo Devido aos impactos ambientais gerados pela indústria da construção civil, pesquisadores têm voltado sua atenção à reinserção de resíduos dentro da própria indústria da construção, entre os quais se encontra o fíler basáltico (FB). Para isso, avaliou-se a composição mineralógica e química do FB, além de aferir o potencial do material passante na peneira de abertura de malha 45 μm como substituição parcial do cimento através da NBR 12653 (ABNT, 2015a). Por conseguinte, foram preparadas argamassas com substituição parcial do cimento Portland por FB nos teores de 0% (REF), 5%, 10%, 15%, 20% e 25% e verificada a resistência à compressão axial aos 28, 63, 90 e 180 dias. Além disso, verificou-se consistência normal e tempos de pega de pastas contendo o fino basáltico. Quanto ao potencial de substituição, conclui-se que FB atendeu aos requisitos químicos avaliados, mas apresentou resultados inferiores aos limites normativos aceitáveis quando avaliada a atividade com cal aos 7 dias - apresentou resultado 89% inferior ao valor de referência - e resistência à compressão axial aos 180 dias - o teor de substituição de 25% apresentou resultado 41,8% inferior comparado a REF. Ademais, o FB mostrou-se uma rocha de caráter básico, cuja morfologia não apresenta material amorfo.
Estudo do comportamento de resinas epoxídicas utilizadas em sistemas de reforço quando expostas ao protocolo de degradação acelerado proposto pela norma ACI 440.9R (2015)
Authors: Dalfré Gláucia Maria , Sarti Júnior Luiz Antônio , Araújo Ciro José Ribeiro Vilella
Published: September 2023

Resumo Atualmente, como alternativa de reforço de elementos de concreto armado, técnicas baseadas no uso de materiais compósitos, tal como a EBR (Externally Bonded Reinforcement, na língua inglesa), aplicada diretamente no substrato de concreto do elemento a ser reforçado com o uso de resinas epoxídicas, têm sido utilizadas. Embora os FRP (Fiber Reinforced Polymers) sejam muito utilizados, o comportamento a longo prazo dos sistemas de reforço ainda é pouco conhecido. Nesse âmbito, o presente trabalho utiliza o protocolo de acondicionamento acelerado proposto pelo código americano ACI 440.9R (2015) para avaliação do comportamento de resinas epoxídicas comumente utilizadas em sistemas de reforço com FRP. Assim, corpos de prova de resina do tipo primer e de saturação foram produzidos e expostos a dois ambientes distintos recomendados pelo ACI 440.9R (2015), laboratorial e degradação acelerado, e ensaiados após um período de 1.000 horas. Os resultados obtidos demonstraram que os adesivos epoxídicos mantidos em laboratório não apresentam reduções estatisticamente distintas de seu módulo de elasticidade e tensão máxima. Entretanto, as resinas expostas ao protocolo de degradação acelerado demonstraram reduções de até 63% do módulo de elasticidade e de até 69% da tensão máxima.
Influência do efeito fíler do pó de mármore na produção de concretos para pavimentos intertravados
Authors: Carvalho Aldo Ribeiro de , Silva Júnior Gilber da , Fontes Wanna Carvalho , Silva Guilherme Jorge Brigolini , Pedroti Leonardo Gonçalves , Oliveira Thaís Mayra de
Published: September 2023

Resumo A produção de resíduos industriais causa impactos ambientais, por isso é importante reintroduzi-los no ciclo produtivo para promover um desenvolvimento mais sustentável. O presente estudo teve o objetivo de investigar o uso do pó de mármore residual como fíler e seus efeitos na produção de concreto para pavimentos intertravados. Para isso, a areia natural foi substituída em 15% e 25% pelo pó de mármore, percentuais pouco usados na literatura de reaproveitamento de resíduos de mármore. Foram avaliadas as propriedades físicas dos materiais utilizados e as características mecânicas e microestruturais dos concretos desenvolvidos. Notou-se que o pó de mármore melhora a trabalhabilidade da mistura e reduz a quantidade de vazios no concreto, resultando em um material mais resistente, denso e homogêneo. As resistências à compressão obtidas pelos concretos foram próximas de 40 MPa, o que atende à norma técnica brasileira para produção de pavimentos intertravados. Verificou-se que a inserção de resíduos no ciclo produtivo é benéfica por otimizar propriedades dos materiais, reduzir o consumo de matérias-primas e os impactos ambientais associados à sua extração.
Estudo das propriedades do gesso de fundição com adição de aditivo hidrofugante
Authors: Lima Karina Paula Barbosa de Andrade , Silva Daniel Bruno Pinto da , Cunha Ana Luíza Xavier , Cavalcanti Kyriale Vasconcelos Morant , Lima Felipe Bezerra de , Araújo Fernanda Wanderley Corrêa de , Holanda Romildo Morant de , Póvoas Yêda Vieira , Medeiros Marcelo Henrique Farias de , Hirota Ercília Hitomi
Published: September 2023

Resumo Ogesso é um material largamente utilizado na construção civil, mas seu uso se restringe a áreas com pouca umidade ou ação da água. O estudo mostra a influência da aplicação de um aditivo hidrofugante comercial na produção de pastas de gesso. O ensaio de absorção de água por imersão total definiu os teores utilizados na caracterização das pastas no estado fresco e endurecido. A absorção de água diminuiu em 1,0% de adição e volta a crescer aos 2,0%, revelando que o teor ótimo do hidrofugante utilizado deve estar entre 0,3% e 1,0%. Na absorção de água por capilaridade, o aditivo apresentou melhor resultado quando utilizado em 1,0%, sendo a mistura classificada como preventiva à água. A resistência à compressão diminuiu em 3,6% e a dureza superficial em até 6,2% nas pastas, quando comparadas às de referência. O aditivo provocou a modificação das propriedades das pastas de gesso no estado fresco e endurecido. A formação da barreira impermeabilizante não foi verificada, e a utilização de maiores teores de hidrofugação poderá ser inviável devido ao elevado custo do aditivo.
Retrospective evaluation of large settlements of a very soft clay: Alameda, California
Authors: Jensen Curtis , Jefferies Michael
Published: September 2023

The Harbor Bay Isle residential project in Alameda, CA, USA, comprises some 600 acres (243 ha) reclaimed from the margin of San Francisco Bay underlain by very soft (C c ∼ 1), high-water-content clay (e 0 > 2): San Francisco Bay Mud. Settlements of as much as 2.5 m developed from about 7 m (varying across the site) of sandfill surcharge, with records over some 43 years extending through primary consolidation and into secondary consolidation (creep). Iterative numerical modelling using large-strain theory (implemented in the Microsoft Excel software program), constrained by in situ void ratios and oedometer trends, achieved close matches with settlement histories over the full 43 years for the three locations considered, each of which displayed a markedly different history from the others. The presence or absence of a dried ‘crust’ was found unimportant; instead, the proportion of subunits within the Bay Mud controlled the evolution of settlements. Subunits within Bay Mud, evident in modern cone penetration test soundings (which were not available during the reclamation works), exist across the region and have systematically different states and properties. Further, while ageing is a factor, depositional conditions of the Bay Mud have produced a residual fabric that presents as a component of the pre-consolidation pressure.
New data on plant hosts of Longidoridae and Trichodoridae nematodes in Türkiye
Authors: Öztürk Lerzan , Behmand Tohid , Öcal Atilla , Avcı Gürkan Güvenç , Elekcioğlu İbrahim Halil
Published: September 2023

In this study, it was aimed to determine nematode species belonging to Longidoridae and Trichodoridae families in agricultural areas of the Thrace Region. The study was carried out between 2015-2022. For this purpose, soil samples were collected from fruit, vegetable, vineyard, and forest areas. Eleven nematode species belonging to Xiphinema, Longidorus, and Trichodorus were obtained from soils around the rhizosphere of 28 plants. Identified species include Xiphinema pachtaicum (26 plants), X. turcicum (grapevine), X. pyrenaicum (grapevine and fig), X.ingens (grapevine), X. italiae (grapevine and olive), X. index (nine plants), X. diversicaudatum (grapevine and fig), X. opisthohysterum (grapevine), Longidorus elongatus (four plants), L. attenuatus (olive and grapevine) and Trichodorus similis (grapevine and walnut). All 22 plants are a new record for nematodes of the Longidoridae and Trichodoridae families in Turkey. This article also includes information generated on a national scale for Xiphinema spp., Longidorus spp., and Trichodorus spp. being identified in Türkiye.
A Theory of Safe Asset Creation, Systemic Risk, and Aggregate Demand
Authors: Altinoglu Levent
Published: September 2023

This paper presents a theory of safe asset creation and the interactions between systemic risk and aggregate demand. The creation of private safe assets by financial intermediaries requires them to take leverage, which generates a risk of future crisis (systemic risk) in which intermediaries liquidate assets to service their debt. In contrast, the creation of public safe assets by the government does not generate systemic risk as the government's power to tax allows it to better absorb losses. The level of systemic risk determines the neutral rate of interest through households' precautionary saving and aggregate demand. The model features a two-way interaction between systemic risk and aggregate demand. Monetary and fiscal policy can stabilize aggregate demand and reduce systemic risk by altering the mix of private and public safe assets held by savers. When monetary policy is constrained, the economy can enter a risk-driven stagnation trap in which economic stagnation arises due to excessive systemic risk. Macroprudential policies which reduce systemic risk can stimulate aggregate demand.
Reduction of specific coke consumption in blast furnace by impact on thermal reverse zone
Authors: Kharchenko A. S. , Sibagatullina M. I. , Kharchenko E. O. , Makarova I. V. , Sibagatullina S. K. , Beginyuk V. A.
Published: September 2023

At the blast furnace of PJSC “Magnitogorsk Metallurgical Plant” (MMK), the specific consumption of coke was reduced by impact on thermal reverse zone (TRZ) by increasing the consumption of natural gas above 120 m3/t of cast iron under conditions of increased reactivity and reduced hot strength of coke. In the first pair of periods, an increase in CRI from 38.4 to 39.3 % with a decrease in CSR from 36.3 to 34.6 % was accompanied by an increase in the ratio of natural gas consumption and total oxygen entering the furnace from 0.43 to 0.45 by increasing the specific gas consumption from 123.2 to 133.5 m3/t of cast iron. The set of actions increased the TRZ length towards the blast-furnace mouth by 1.9 % with its unchanged location along the lower part. Reducing the heat consumption in the TRZ increased the temperature difference between gas and materials there by an average of 36 °С. In the second pair of periods, the consumption of natural gas was 143.9 m3/t of cast iron with a decrease in the oxygen content in the blast from 27.6 to 27.0. They were accompanied by the following changes in the processes under consideration: an increase in the length of the TRZ towards the blast-furnace mouth by 2.6 % and the distance from the tuyere hearth by 3.4 %, an increase in the degree of carbon reduction from 32.0 to 33.3 %, an insignificant (on average 0.3 °С) increase in the temperature difference of gas and materials in the TRZ. In the first pair of periods, reduction in the coke specific consumption was 4.7 kg/t of cast iron with an increase in furnace productivity by 27 t/day. Conditions and course of the processes of the second pair ensured a decrease in the coke specific consumption by 1.6 kg/t of cast iron and led to a decrease in cast iron production by 41 t/day.
Sintered powder high-entropy target cathodes for wear-resistant coatings
Authors: Grigor’ev S. N. , Migranov M. Sh. , Volosova M. A. , Gusev A. S.
Published: September 2023

Modern machine-building production equipped with high-performance mechatronic systems and numerically-controlled and adaptive control machines for blade cutting of heat-resistant chromium-nickel and titanium alloys requires increasing the operating properties of cutting tools working at high temperature-force loads in the contact zone, respectively with a significant stress-strain state of the cutting wedge. It is possible to solve the problem of increasing wear resistance and serviceability by developing and introducing new tooling material, as well as by applying wear-resistant coatings. The paper presents the results on development of technology for obtaining high-entropy target cathodes by spark plasma sintering with subsequent application of wear-resistant coatings on metal-cutting tools by both magnetron and ion-plasma methods. Samples of sintered high-entropy target cathodes of different compositions (more than fourteen) and at different modes of their sintering (depending on temperature in five modes) with their subsequent optimization and two standard sizes (20 and 80 mm) were obtained for further application of wear-resistant coatings on the magnetron unit. The authors carried out structural and phase analysis and studied physicomechanical properties of the obtained high-entropy target cathodes: density, hardness, electrical conductivity, emissivity. The possibility of obtaining high-entropy target cathodes by spark plasma sintering was confirmed experimentally, and the effect of sintering temperature on structure and properties of the sintered samples of high-entropy target cathodes was established. Dependence of physicomechanical and electrophysical parameters of target cathodes on technological modes of spark plasma sintering is shown.
Effect of ring groove in a heat-insulating insert on efficiency of its work in blast channel of blast furnace tuyere
Authors: Albul S. V. , Kobelev O. A. , Levitskii I. A.
Published: September 2023

One of the main disadvantages when supplying natural gas to the air tuyere of a blast furnace is low intensity of its combustion inside the tuyere blast channel. Ring groove on the surface of blast channel improves the mixing of natural gas with blast and increases completeness of gas combustion in it, but reduces the tuyere durability. One of the ways to simultaneously solve these problems is to install a heat-insulating ceramic insert in the tuyere blast channel. The insert significantly reduces heat losses through the tuyere surface, improves natural gas combustion in the blast channel due to its contact with hot walls of the insert instead of cold copper walls in its absence. This increases the temperature of the hot blast at the tuyere outlet. In addition, the insert affects the tuyere durability by reducing the heat flow acting on the tuyere. In this work, we studied influence of the ring groove and its parts in the insert on efficiency of its work. In the Ansys 21.1 software, the processes occurring in the blast channel of a blast furnace tuyere with a ceramic insert installed in it, having a groove of a quadrangular section in the form of a ring or its part in the circumferential direction, were simulated. It was established that improvement of natural gas combustion in the tuyere blast channel is achieved using a ring groove or part of it from the side of gas supply.
High-temperature strength of die steel with regulated austenitic transformation during exploitation after quenching and tempering
Authors: Kruglyakov A. A. , Rogachev S. O. , Molyarov A. V.
Published: September 2023

Steels with regulated austenitic transformation during exploitation (RATE) are a new class of ferritic-based tungsten-free tool steels for hot forming. The study obtained quantitative data on the high-temperature strength of RATE steel of new composition after quenching and tempering. The stress-strain curves are plotted and the tendency of steel to strain hardening at temperatures of 450 and 750 °C is estimated. It was established that at a temperature of 750 °C, corresponding to the operating temperature, RATE steel has a stronger tendency to work hardening than at a temperature of 450 °C.
Stress state of billet – mandrel system during production of hollow steel billet in a unit of continuous casting and deformation. Part 1
Authors: Lekhov O. S. , Mikhalev A. V. , Nepryakhin S. O.
Published: September 2023

The substantiation of the relevance of obtaining continuous cast steel pipe hollow billet is given from the position of improving the quality of pipes made of carbon and alloy steels is given. The article presents an assessment of the quality of the inner surface of pipes made of solid steel pipe billet. A new technology is proposed for the production of hollow steel pipe billets on a resource-saving unit of combined continuous casting and deformation. The photo of the continuous casting and deformation section of JSC Ural Pipe Plant is given, where a pilot unit of combined continuous casting and deformation is installed. The paper presents the results of a theoretical study of stress-strain state of the mandrel and sections of a pipe billet when it is compressed by the strikers of the unit of combined continuous casting and deformation. The authors discuss the general model of the mold – striker system. The initial data on calculation, dimensions of the hollow pipe billet and a description of the calibration of strikers for compression of a hollow steel billet are given. The temperature field of a hollow billet was determined. To simulate the stress-strain state of the metal in the roll pass and the mandrel, four contact pairs were considered. Calculations were made by the finite element method. The dimensions of the final element in the roll pass of hollow billet were determined. The authors established the values and patterns of changes in metal displacements and axial stresses in the roll pass during the production of hollow steel billets in the unit of combined continuous casting and deformation (strikers are made along a constant radius). The stress state of metal in the roll pass was assessed from the standpoint of improving the quality of hollow steel billets.
Institutionalization of ESG-principles at the international level and in the Russian Federation, their impact on ferrous metallurgy enterprises. Part 2
Authors: Glushakova O. V. , Chernikova O. P.
Published: September 2023

Currently, a new development trend is being formed in the world associated with the decarbonization of economies. This process is based on the institutionalization of ESG-principles – an approach to doing business, characterized by the involvement of companies in solving environmental, social and governance problems. The process of institutionalization of ESG-principles at the international level was initiated in 1948 with the adoption of the Universal Declaration of Human Rights under the auspices of the UN. The active involvement of Russia in the formation of the institutional framework in the field of ESG has begun only in 2020. The reason for this was the ratification of a number of international documents, as well as the active promotion of climate policy by many countries of the world. The stages of the institutionalization process at the international level discussed in detail in Report 1. The decarbonization of economies creates development risks for industries whose products are characterized by high carbon and energy intensity. Ferrous metallurgy also belongs to them. This report presents the results of a study of the effectiveness of measures taken by the Russian Government in the field of reducing atmospheric air pollution in large industrial centers of the ferrous metallurgy based on data from the Unified Information System for Monitoring Air Quality, as well as the results of an analysis of the ESG-practices of the largest Russian ferrous enterprises and compliance with carbon intensity and energy intensity of their products according to the criteria of sustainable (including green) development projects established in our country. As a result of the study, it was found that despite the use of ESG-principles in their activities, the specific emissions of CO2-equivalent of the largest iron and steel enterprises significantly exceed the criteria for sustainable (including green) development projects established by the Russian Government.
The primary assessment of the industrial strategic priorities effectiveness
Authors: Sasaev N. I.
Published: September 2023

Industrial development is one of the most important areas contributing to the achievement of the strategic goal of ensuring the socio-economic development of any state or region. The success of the implementation of the designated goal is seen through a comprehensive process of strategizing industrial objects for a long period of time, namely through the effective development and implementation of signifi cant strategic priorities, which is especially relevant and important in post-normal conditions.Meanwhile, the complex work of strategy developers at the fi rst stage determines a long list with concepts of industrial strategic priorities, the implementation of each of them requires a certain provision, while the strategizing object has a limited supply of resources and time. Thus, it is necessary to select from this long list those strategic priorities that will give the highest effi ciency with the least expenditure of resources and time.In the article, the author proposes an expanded methodology for the primary assessment of the industrial strategic priorities effectiveness, which includes the process of parameterization of indicators for the estimated effects of industrial priorities, modeling and evaluation of the studied effects, the process of ranking industrial strategic priorities.The proposed methodology for evaluating the primary assessment of the industrial strategic priorities effectiveness allows ranking them at the fi rst stages of strategizing and forming a short list, on the basis of which the strategy development team will continue to work on detailing, formalizing and compositioning all developed elements at the conceptual level into a single fi nal document – an industrial strategy. In addition, the author describes the main features, principles and assumptions of the extended methodology.
Implementation of management decision-making methods based on foresight in order to increase the sustainability of high-tech enterprises
Authors: Kazmina I. V.
Published: September 2023

The article analyzes the scientifi c methods of managerial decision-making at hightech enterprises. It is determined that the stability of production and the competitiveness of the enterprise in the domestic and foreign markets are determined by such a parameter as the stability of the functioning of the enterprise, which is considered as a predictable parameter characterizing the state of a high-tech enterprise. Increasing the stability of the enterprise can be achieved through the systematic analysis of special indicators that determine the integrated stability in the complex. When predicting the stability of the functioning of a high-tech enterprise, it is necessary to use various methods. Based on the analysis of existing methods of scientifi c prediction of indicators and characteristics of industrial enterprises for making managerial decisions and their features, forecasting methods are identifi ed, combined into the following groups: mathematical (statistical) forecasting methods; computational methods of multi-stage forecasting based on artifi cial neural networks, which are part of the digital twin software in an industrial company; expert forecasting methods involving the use of intuition, knowledge and expert assessments. The integral stability of the functioning of a high-tech enterprise is developed under the infl uence of a complex of factors of the macro environment and the internal environment of the enterprise. They are grouped depending on the environment of occurrence, the nature and direction of the impact, the object of the impact. It is revealed that increasing the stability of the functioning of high-tech enterprises can be ensured by a comprehensive system analysis of the main directions of assessing the stability of the functioning of the enterprise and their subsequent correction, if necessary. The directions of increasing the stability of the functioning of high-tech enterprises, allowing to ensure the stability of the enterprise, are presented.
Достижения перинатальной реформы и резервы дальнейшего сокращения младенческой смертности в России
Authors: Макаренцева Алла Олеговна
Published: September 2023

В статье раскрывается динамика младенческой смертности в России после так называемой перинатальной реформы 2012 г. Несмотря на достижение низких показателей в целом (4,4 промилле в 2022 г.), в структуре младенческой смертности неоправданно высокой остается доля постнеонатальной смертности, а доля неонатальной смертности существенно ниже, чем в других развитых странах. Анализ причин смерти показывает, что вклад предотвратимых причин остается высоким. Так, несмотря на то, что за последнее десятилетие основное снижение смертности пришлось на класс «отдельные состояния, возникающие в перинатальном периоде» (с 48,1 до 23,4 на 10 тыс. родившихся живыми), доля этого класса от числа всех умерших на первом году жизни снизилась незначительно, с 56 до 51%. По результатам эконометрического анализа автор утверждает, что наличие организаций третьего уровня родовспоможения вносит существенный вклад в сокращение младенческой смертности на региональном уровне. Анализ проблемы преждевременных родов демонстрирует ее значительный вклад в показатели младенческой смертности. В завершение автор предлагает ряд шагов в организационно-медицинской части, а также в части расширения связанных статистических и аналитических возможностей в целях дальнейшего сокращения младенческой смертности в России.
Переменчивые тенденции рождаемости в Узбекистане: 1991-2021 гг.
Authors: Абдурахманов Абдуазим Джалалитдинович
Published: September 2023

В статье приводятся оценки основных показателей рождаемости в Узбекистане в 1991-2021 гг., полученные на основе опубликованных и неопубликованных официальных данных Агентства по статистике при Президенте Республики Узбекистан. Интерпретация разнонаправленных изменений в уровне рождаемости, имевших место в последние десятилетия, требует проведения углубленных социологических и статистико-демографических исследований, которых явно недостаточно в республике. Необходимо также провести экспертную оценку качества исходной информации о численности и составе населения, основу для которой предоставит первая всеобщая перепись населения независимого Узбекистана, запланированная на 2023 г.
Field sampling for drinking water v1
Authors: Shrestha Sneha
Published: September 2023

The method we used for sampling drinking water for households when detecting S. Typhi and Paratyphi in Nepal
DSBEST v2.0 (Caroe et al. 2018) v1
Authors: Grealy Alicia
Published: September 2023

This bench protocol is based on the work of Caroe et al. (2018), for preparing shotgun libraries from double-stranded DNA, typically for ancient and degraded DNA. Please cite Caroe et al. (2018) if you use this bench protocol!
hyRAD (Suchan et al. 2016; Grealy et al.) v1
Authors: Grealy Alicia
Published: September 2023

This bench protocol is based on the work of Tomasz Suchan, for performing hyRAD with RNA baits, with some changes.
Leucemia promielocítica aguda. Estado del arte
Authors: Mejía-Buriticá Leonardo , Torres-Hernández José Domingo , Vásquez Gonzalo de Jesús
Published: September 2023

La leucemia promielocítica aguda (LPA) es un subtipo de leucemia mieloide aguda (LMA) que se origina por una traslocación balanceada entre los cromosomas 15 y 17, involucra al gen que codifica para el receptor alfa del ácido retinoico (RARA) en el cromosoma 17 y el de la leucemia promielocítica (PML) en el cromosoma 15, lo que da origen a la traslocación t(15;17) PML/RARA. Dicho reordenamiento origina la proteína de fusión PML/RAR alfa, que bloquea la diferenciación de las células madre mieloides en el estadio de promielocito. La LPA afecta con mayor frecuencia a adultos jóvenes y conlleva un alto riesgo de mortalidad temprana, en especial por el desarrollo de una coagulopatía grave, que sin tratamiento es definitivamente fatal. El diagnóstico temprano, el tratamiento de soporte y la introducción de fármacos que promueven la diferenciación terminal de los promielocitos patológicos como la tretinoina, también conocida como ácido todo transretinoico (ATRA) o trióxido de arsénico (ATO), ha hecho que en la actualidad esta sea una enfermedad curable con altas tasas de remisión completa.
Características sociodemográficas y clínicas, según el índice CD4:CD8, de una población de personas infectadas con el VIH que consultó en la Corporación para Investigaciones Biológicas de Medellín, Colombia
Authors: Villegas-Arbeláez Esteban , Botero-Garcés Jorge Humberto , Alzate-Ángel Juan Carlos
Published: September 2023

Introducción: las personas infectadas con el virus de la inmunodeficiencia humana tipo 1 (VIH-1+) con un índice CD4:CD8 menor a 1, presentan un mayor riesgo de morbilidad y mortalidad por eventos no asociados con el SIDA. El objetivo de este trabajo fue explorar‚ en la población seleccionada‚ variables sociodemográficas y clínicas de acuerdo con dicho índice, debido a que este es más informativo que LT CD4+ y LT CD8+ por sí solos.

Materiales y métodos: estudio observacional en pacientes con VIH-1+ atendidos en la Corporación para Investigaciones Biológicas (CIB). En 227 pacientes se evaluaron diferencias en edad‚ recuento de LT CD4+‚ carga viral‚ número y tipo de esquemas. Se dividieron los pacientes en dos grupos: (A con índice CD4:CD8 ≥ 1 y, B < 1).

Resultados: el estudio se compuso de la siguiente forma, 71 % hombres y 29 % mujeres. El 22,5 % pertenecía al grupo A y el 77,5 % al B. La media de la edad fue 42‚8 años en el grupo A y 45 en el B (p = 0‚176). El 100 % de los individuos en el grupo A recibían tratamiento y, 97‚7 % en el B. La media de LT CD4+ fue de 772‚4 para el grupo A y, 448‚1 en el B (p = 0‚00001). En el grupo A el 90‚2 % tenían carga viral indetectable‚ en contraste con el 68‚8 % del B (p = 0‚002). El 41‚2 % en el grupo A tuvieron un solo esquema‚ en relación con el 43,8 % del B (p = 0‚744).

Conclusiones: la mayoría de los pacientes presentaron un índice CD4:CD8 < 1 a pesar de haber presentado LT CD4+ aceptables. Fue más frecuente encontrar un índice < 1 en los pacientes sin un adecuado control virológico. Se requieren más estudios para determinar las variables asociadas con su normalización.
Tratamiento médico exitoso de una osteomielitis multifocal neonatal producida por la bacteria Staphylococcus aureus meticilina resistente (SAMR). Revisión de caso
Authors: Franco-Patiño María Camila , Chanci-Drago Romario , Taborda-Alzate Érika Alexandra , Arango-Rivera María Victoria
Published: September 2023

La osteomielitis (OM) en el periodo neonatal es una condición rara y trascendental. Su incidencia estimada corresponde al 0,1 de casos por cada 100 admisiones hospitalarias. El subdiagnóstico es frecuente dada la presentación paucisintomática de este grupo etario, que lleva a demoras en el inicio del tratamiento y puedeconducir a secuelas permanentes. Presentamos un caso de osteomielitis multifocal con fracturas asociadas, causada por la bacteria Staphylococcus aureus meticilina resistente (SAMR), secundaria a una infección asociada a catéter en un neonato nacido a las 37 semanas de gestación, con antecedente de asfixia perinatal y encefalopatía hipóxica isquémica. El caso debutó con sepsis, edema y artritis, pero el diagnóstico fue confirmado con ultrasonografía y radiografías que evidenciaron múltiples fracturas patológicas. Al no ser candidato para el manejo quirúrgico, se concertó una adecuación del esfuerzo terapéutico dirigiendo el manejo a la terapia antibiótica de amplio espectro y al control del dolor con adecuada respuesta clínica.
Tuberculosis urogenital en un paciente con falla renal, estado del arte
Authors: Nieto-Ríos John Fredy , Zea-Lopera Julián , Sánchez-López Sebastián , Barrientos-Henao Santiago , Bello-Márquez Diana Carolina , Vélez-Hoyos Alejandro , Serna-Higuita Lina María
Published: September 2023

La tuberculosis es una enfermedad infecciosa y frecuente en países en vía de desarrollo. Esta puede causar una amplia variedad de complicaciones y presentaciones atípicas con alta morbimortalidad. De la forma genitourinaria se sospechada muy poco, razón por la cual su diagnóstico se hace, usualmente, de forma tardía o no se realiza. Esto conlleva a consecuencias muy graves en los pacientes, por ejemplo, la enfermedad renal crónica terminal. A continuación, se presenta un reporte de caso de una paciente con la anterior enfermedad, secundaria a una tuberculosis renal bilateral diagnosticada tardíamente y se realiza una revisión de la literatura sobre este tema.
Efficacy of anthelmintic drugs to control Fasciola hepatica in dairy cattle in Peru
Authors:   Universidad  Nacional  de  Cajamarca,, Rojas-Moncada Juan , Saldaña Luz ,   Universidad  Nacional  de  Cajamarca,, Urteaga Víctor ,   Universidad  Nacional  de  Cajamarca,, Vergara Roxana ,   Universidad  Nacional  de  Cajamarca,, Rojas Anthony ,   Universidad  Nacional  de  Cajamarca,, Torrel Severino ,   Universidad  Nacional  de  Cajamarca,, Murga-Moreno César ,   Universidad Nacional de Cajamarca,, Vargas-Rocha Luis ,   Universidad  Nacional  de  Cajamarca,
Published: September 2023

Background: Decreasing antiparasitic efficacy of triclabendazole for controlling Fasciola hepatica in dairy cows in the Cajamarca Valley (Peru) has been reported. Objective: To determine the efficacy of four anthelmintic agents across a broader area of Cajamarca province. Methods: Four livestock farms were selected from three provinces in the Cajamarca region. Within each farm, 60 female cattle naturally infected with F. hepatica were chosen. Each farm was divided into four homogeneous groups based on individual animals and parasite burden. The groups were: triclabendazole (12 mg/kg of BW, VO), clorsulon/ivermectin (2 mg/kg and 0.2 mg/kg of BW, SC, respectively), closantel (10 mg/kg of BW, VO), and nitroxynil (10 mg/kg of BW, SC). Efficacy was determined following WAAVP guidelines by measuring the reduction in trematode egg shedding on day 30 post-dosing. Results: Triclabendazole demonstrated insufficient activity through FERCT and CPCR assessments across all four farms. The clorsulon/ivermectin and closantel groups exhibited high efficacy in all farms, while nitroxynil showed varying efficacy results in both types of analysis. Conclusions: Triclabendazole exhibited insufficient activity against F. hepatica. Clorsulon/ivermectin, closantel, and nitroxynil are viable alternatives with promising outcomes for controlling this trematode in the evaluated provinces.