bluuebunny/crossref_metadata_2025 huggingface dataset:
Peripheral lymphadenopathy and FNA: a two-year evaluation at a tertiary care centre
Authors: Ninan Jiby Soosen , Alba De Souza Johanna , Philipose Thoppil Reba
Published: January 2019

Background: Lymphadenopathy is an age old affliction of mankind and a very common presentation in clinical practice. The main purpose of an FNA biopsy of abnormal peripheral lymph nodes is to determine whether further surgical excision of the lymph node is indicated for histopathological examination. The aim of the present study was to evaluate the role of fine needle aspiration cytology in patients with superficial lymphadenopathy and to correlate with histopathology wherever possible.Methods: A two-year study was undertaken at the Central Diagnostic Laboratory at A.J. Institute of Medical Sciences, Mangalore. Patients of all age groups referred to the Central Diagnostic Laboratory for FNA of superficial lymph nodes were included in the study. All the slides of the cases were reviewed and impression recorded.Results: Out of 200 cases, 73% were non neoplastic, 27% were neoplastic. Cases occurred most commonly in age group of 21-30 years. The male to female ratio was 1.7:1 and most common site of lymph node aspiration was cervical lymph node in (n =107) 53.5% cases. Reactive hyperplasia was the most common non- neoplastic cause of lymphadenopathy seen in 34.5% cases and metastasis to lymph node was the most common cause of neoplastic lymphadenopathy seen in 22% of the cases. The sensitivity was 90%, specificity was 100% and accuracy was 96.2%.Conclusions: FNA is a very efficient, simple, safe, inexpensive and economical test for detecting the various causes of lymphadenopathy.
Intestinal fatty acid binding protein (I-FABP) as a marker for acute intestinal ischemia
Authors: U. Girish T. , Hegde Ajay
Published: January 2019

Background: Acute mesenteric ischemia accounts for around 0.1% of all hospital admission and less than 1% of emergency admissions. However, the presentation is varied, and diagnosis is obscure. The diagnosis of intestinal ischemia demands a high index of suspicion. The overall mortality associated with mesenteric ischemia is between 60% and 93% but rises acutely once bowel wall infarction has occurred. Early diagnosis of ischemia remains the key to reduce morbidity and mortality. I-FABP is a cytosolic protein present in epithelial cells of intestines and released upon ischemia or necrosis of bowel. Author estimated the levels of I-FABP in serum and established it as a marker for acute intestinal ischemia.Methods: 40 patients admitted to JSS Hospital with suspected acute intestinal ischemia were included in the study. Plasma concentrations were quantified using ELISA for fatty acid binding protein 2. Statistical methods were applied and sensitivity and specificity of serum I-FABP were determined. Confirmation of ischemia was by histopathological analysis of the resected bowel specimen.Results: 23 patients out of the 40 were diagnosed to have intestinal ischemia.  Mean values of serum IFABP levels were significantly higher in patients diagnosed with intestinal ischemia (65.94pg/ml in the non-ischemic group vs 673.53pg/ml in the ischemic group P=0.0002). Cut off chosen in diagnosing intestinal ischemia in this study was 187.59pg/ml. Sensitivity was 95.7% and specificity 88%.Conclusions: Serum I-FABP can be used for the diagnosis for intestinal ischemia. It is specific and sensitive marker to detect early bowel ischemia.
Evaluation of Workload and Human Errors in Nurses
Authors: Naseri Karimvand Mahshid , Hasheminejad Naser , Faghihi Zarandi Ali , Jahani Yones
Published: January 2019

Background: Identification of human errors and their related factors in nurses dealing with the health of humans is important. Considering that much workload can increase the risk of human error, this study aimed to investigate the relationship between workload and human errors among nurses working in educational hospitals of Kerman University of Medical Sciences. Methods: This descriptive-analytical study was performed on 145 nurses from educational hospitals affiliated to Kerman University of Medical Sciences in 20. The workload was evaluated using the NASA-TLX questionnaire and human errors with SHERPA technique. The statistical test used was logistic regression model and the statistical significance level was considered <0.05 and the samples were selected randomly. The sample size was selected based on the percentage of functional errors reported by a study on human error assessment related to the duties of nurses in Semnan. Results: A total of 138 probable errors were detected in the nursing staff of these hospitals, 74% of nurses committed errors in seven main duties during their service. Patient medication with the highest frequency (34%) followed by the injection of the drug to the patient with a frequency of 23% were the most frequently committed errors by nurses. The findings of the research showed that workload in 53.1% of the nurses was very high and in 43.1% of the nurses was high, the results of the logistic regression model showed that there was no significant relationship between errors and workload in nurses. Conclusion: The results of the study showed that the average workload and human error in the nurses were high. Therefore, control strategies such as holding training sessions, implementation of clinical governance program in all wards, recruitment of adequate nurses, reduction of workload, reduction of work hours and the appropriate patient/nurse ratio should be given attention by the hospital managers depending on conditions; as well as the prevention of the two reported errors should be given top priority in corrective measures.
Effective Safety and Health Measures in Preventing H2S Poisoning among Wastewater Network Operators
Authors: Razeghi Omid , Hormozi Behrouz , Hormozi Akbar
Published: January 2019

Background: Waste water networks were constructed and established to collect and transfer the swage in cities. In this regard, the occupation related to the operation of wastewater networks was created and flourished to improve and study the application of networks. One of the hazards that threaten the life of wastewater operators is poisoning by inhalation of hydrogen sulfide gas produced by wastewater. The aim of this study was to investigate the effective safety and health measures in prevention of hydrogen sulfide gas poisoning among the wastewater network operators. Methods: This qualitative study was carried out on 23 operators who worked in the main lines of wastewater transfer in Tehran. In order to collect the data, we used the focused group discussion in five months; from August 1, 2017 to the end of December 2017. The results were collected using the databases' analysis and the focused group discussions. The collected information was implemented and practiced in various maneuvers under probable scenarios and the possibility of operating them was investigated.Results: The average age of participants was 34.8 years and they were in the range of 24- 51 years. Participants were male and their educational degrees included diploma and lower degrees (N =4), bachelor's degree (N =11), and master's degree (N =3). The effective control measures to prevent H2S poisoning were classified into three categories of engineering controls, managing controls, and using the personal protective equipment. Conclusion: The results showed that the highest frequency of efficient control measures was related to engineering controls, which indicated the high effect of engineering maneuver on the prevention of H2S poisoning among operators of wastewater networks. Management controls and use of personal protective equipment were in the next steps, respectively. In order to have complete efficiency, we should consider the control measures in all three areas.
Effect of Storage Time of a Ceramic Primer on Microshear Bond Strength to Zirconia
Authors: Ghasemi Amir , Sadr Alireza , Pourhashemi Anahita
Published: January 2019

Objective: This study assessed the effect of shelf life of a ceramic primer containing 10-methacryloyloxydecyl dihydrogen phosphate (MDP) monomer on microshear bond strength of zirconia ceramic to composite resin.
Materials and Methods: Sixty-four sintered zirconia samples (1.5×5×7 mm) were pretreated with Clearfil Ceramic Primer (CCP) at baseline and after one, two and six months of storage at 6°C. Composite cylinders were fabricated using Tygon tubes (1 mm height, 0.7 mm diameter) and placed on treated zirconia blocks, light-cured and subjected to microshear bond strength test. Mode of failure was determined under a stereomicroscope. Fourier-transform infrared spectroscopy (FTIR) was performed at each storage time point. Data were analyzed using one-way ANOVA and Tukey’s test. 
Results:  Significant differences were noted in microshear bond strength after six months of storage compared to baseline (P<0.05). Significant differences were noted in FTIR spectra at the four time points (P<0.05).
Conclusions: The effectiveness of one-component ceramic primer in bonding to zirconia was significantly affected by the storage of this material in a time-dependent manner. Visible new peaks and changes in FTIR spectra over time indicated alterations in the composition of ceramic primer affecting its shelf life.
Evaluation of the Effect of MTAD on Expression of Enterococcus faecalis Virulence Factors Considering the Role of Different Obturating Materials
Authors: Bolhari Behnam , Bahador Abbas , Khoshkhounejad Mehrfam , Sobhi Afshar Mahsa , Moghaddaszadeh Mohammad
Published: January 2019

Objectives: The aim of this study was to determine the effect of MTAD on the expression of virulence factors of Enterococcus faecalis (E.faecalis) considering the role of Gutta-percha/AH26 or Resilon/RealSeal SE as root canal obturating materials.
Materials and Methods: One-hundred and forty-four single-rooted human teeth were instrumented to a standardized apical size. Root canals were infected by E.faecalis (ATCC 29212). Ninety teeth were irrigated with MTAD and randomly divided into three groups. In two groups, root canals were obturated by either Gutta-percha/AH26 or Resilon/RealSeal SE. Root canals were kept unobturated in the third group. The remaining 54 teeth received no final irrigation. All groups were then subdivided into three timepoint subgroups in which dentin powder was obtained from each sample to determine the expression of specific virulence factors of E.faecalis (efa, esp, gel, fsr) using real-time reverse transcription polymerase chain reaction (RT-PCR). Statistical analysis was performed by one-way analysis of variance (ANOVA) and Tukey’s post-hoc test. The statistical power was set at P-value ≤0.05.
Results: MTAD was effective against the expression of most of the tested virulence factors, and Gutta-percha/AH26 increased the antibacterial efficacy of MTAD.
Conclusions: MTAD could inhibit the expression of some known virulence factors of E.faecalis at the majority of tested timepoints. This may partly explain some of the mechanisms of antimicrobial efficacy of MTAD against this resistant microorganism which is known as one of the main causes of failure of root canal treatment.
بررسی سطح بازاندیشی در زمینه یافته های آموزشی در دانشجويان دندانپزشكي دانشگاه علوم پزشکی شهید صدوقی یزد در سال 97-1396
Authors: کاظمی پوز مریم , حکیمیان رقیه
Published: January 2019

مقدمه: بازاندیشی و تجزيه و تحليل يافته هاي آموزشي يكي از اصولي و اساسي ترين مراحل در روند يادگيري محسوب مي گردد. از اینرو مطالعه حاضر با هدف بررسی سطح بازاندیشی در زمینه یافته های آموزشی در دانشجويان دوره عمومی رشته دندانپزشكي دانشگاه علوم پزشکی شهید صدوقی یزد انجام شد.
روش بررسی: در اين مطالعه توصيفي-مقطعي204 نفر از دانشجويان رشته دندانپزشكي(ترم هاي 7 تا 12) دانشگاه علوم پزشكي شهید صدوقی یزد در سال تحصيل97-1396 شركت نمودند. در اين مطالعه از پرسشنامهKember  (Reflection Questionnaire-RQ)  باروایی 82/0 وپایایی (آلفا کرونباخ )78/0استفاده شد. آناليز داده ها با استفاده از نرم افزار آماري SPSS 17 و آزمونهاي آماريT–test, ANOVA  و ضريب همبستگي پيرسون انجام شد. سطح معنی داری 05/0≥P تعیین گردید.
نتایج: در مطالعه حاضر 204 دانشجوی دوره عمومی دندانپزشکی، شامل 117(4/57درصد) زن و 87 (6/42 درصد) مرد، با میانگین سنی 36/2±17/24سال با دامنه سنی 21 تا 42 سال، شرکت داشتند. میانگین نمره حیطه ی عملکرد از روی عادت 88/2±11/10، حیطه ی درک مطلب 16/4±87/14، بازاندیشی 94/2±04/16 و بازاندیشی انتقادی 58/2±86/13 گزارش گردید. بین سه سال تحصیلی در میانگین سطح بازاندیشی و بازاندیشی نقادانه اختلاف آماری معنی داری وجود داشت(05/0>P). همچنین بین دو گروه سنی (24˂ و24≤ سال) اختلاف آماری معنی داری در حیطه های عملکرد از روی عادت و بازاندیشی نقادانه بود(05/0>P).
نتیجه‌گیری: بر اساس نتایج مطالعه حاضر با افزایش سن و سال تحصیلی سطح عملکرد از روی عادت در دانشجویان دندانپزشکی کاهش یافته است. از اینرو پیشنهاد می گردد که در دانشکده های دندانپزشکی برآموزش بازاندیشی در ترمهای تحصیلی پایین تر تاکید گردد.
Role podstatných náležitostí demokratického právního státu v ústavní praxi České republiky
Authors: Tomoszek Maxim
Published: January 2019

Rola zasadniczych wymagań demokratycznego państwa prawnego w praktyce konstytucyjnej Republiki Czeskiej. Kiedy definiujemy treść istotnych elementów demokratycznego państwa prawa, należy wziąć pod uwagę w szczególności fakt, że ta koncepcja odgrywa pięć moż­liwych ról w systemie konstytucyjnym Republiki Czeskiej: klauzula wieczności, ramy odniesienia w przeglądzie konstytucyjnym, materialny rdzeń konstytucji, tożsamość konstytucyjna Republiki Czeskiej oraz zestaw podstawowych wartości czeskiej konstytucji. Niezbędne elementy demokra­tycznego państwa prawa, w związku z ideami założycielskimi Konstytucji Republiki Czeskiej, za­wierają element uniwersalny i szczególny. Trudno sobie wyobrazić tożsamość konstytucyjną, która tylko powiela konstytucyjne tożsamości innych państw, z drugiej strony nawet w czeskiej tożsa­mości konstytucyjnej z pewnością jest miejsce dla czeskich twórców konstytucyjnych, by zaakcep­tować uniwersalne zasady uznane w rodzinie zachodnich demokracji. To dalej określa szczególne zasady rozumiane jako podstawowe elementy demokratycznego państwa prawa w rozumieniu art. 9 ust. 2 czeskiej konstytucji.
Prezydencja Republiki Czeskiej w pierwszym półroczu 2009 roku jako przykład skutecznego zarządzania Unią Europejską
Authors: Witkowska-Chrzczonowicz Katarzyna
Published: January 2019

W artykule przedstawiono zalety i wady czeskiej prezydencji w Radzie Unii Eu­ropejskiej (styczeń–czerwiec 2009 r.). Prezydencja czeska była jedną z najciekawszych prezydencji ostatnich lat. Republika Czeska była dopiero drugą (po Słowenii) prezydencją państwa z grupy kra­jów, które przystąpiły do Unii Europejskiej podczas „wielkiego rozszerzeniaˮ w 2004 roku. Prezy­dencja czeska rozpoczęła w bardzo trudnym dla Unii czasie (tj. głębokiego kryzysu gospodarczego w większości państw członkowskich UE, konfliktu gazowego między Rosją i Ukrainą, wojny w Gru­zji, wyborów prezydenckich w USA, braku ratyfikacji traktatu lizbońskiego). Co więcej, w Republice Czeskiej panowała bardzo skomplikowana wewnętrzna sytuacja polityczna, w tym dymisja czeskiego rządu w połowie czeskiej prezydencji UE i eurosceptycyzm prezydenta Klausa. Jednak prezydencja czeska zasługuje na pozytywną ocenę. Z punktu widzenia administracji prezydencja była bardzo do­brze przygotowana, choć w momencie obalenia rządu w czasie prezydencji czeska klasa polityczna poniosła porażkę. Republika Czeska okazała się państwem członkowskim Unii Europejskiej, które dostrzega nowe wyzwania stojące przed UE i rozumie jej filozofię i mechanizmy. Czesi przyjęli per­spektywę unijną i wykazali znacznie większe zrozumienie dla wspólnych ideałów niż państwa człon­kowskie o znacznie dłuższym członkostwie i znaczącej pozycji politycznej.
Prostytucja i jej nowe formy oraz zjawiska pokrewne a regulacje prawne
Authors: Szota Paulina
Published: January 2019

Publikacja ma na celu przedstawienie zjawiska prostytucji i form jej podobnych. W artykule zostały przedstawione różne sposoby definiowania terminu prostytucja, autorka opisała również inne zjawiska, które przybierają postać nierządu, wraz z ich uwarunkowaniami. Opisane zostały konkretne przepisy prawa karnego, a także akty międzynarodowe, które problematykę prostytucji regulują wprost. W podsumowaniu autorka rozważa kwestie uregulowań prawnych dotyczących prostytucji oraz jej rozwoju.
“De tanto poupar em educação ficaremos ricos em ignorância”: contranarrativas juvenis no movimento de ocupação de escolas no Rio Grande do Sul
Authors: Ketzer Araciele Maria , Rosa Rosane
Published: January 2019

O movimento de ocupação das escolas públicas brasileiras por estudantes secundaristas no período de 2015-2016 constituiu um fenômeno que evidenciou o protagonismo juvenil e pautou a precariedade da educação básica nas discussões da agenda pública e midiática. Além de ocupar as escolas e as ruas, os/as estudantes ocuparam as redes sociais, como o Facebook, para expressar suas opiniões e demandas. Partindo desse cenário, nosso objetivo central é investigar como os/as estudantes secundaristas do Rio Grande do Sul mobilizaram-se e apropriaram-se das redes sociais para construir uma comunicação de resistência e sua autorrepresentação. Para tanto, utilizaremos uma combinação de abordagens metodológicas, como a pesquisa exploratória, entrevistas semiestruturadas e a observação online-sistemática das páginas, no Facebook, das escolas ocupadas pelos estudantes entrevistados. Como resultado, podemos destacar a existência de uma gestão participativa e colaborativa, a capacidade de mobilização, postura crítica e política em relação à mídia hegemônica, propositiva em relação à educação pública, e o uso de criativas estratégias e linguagens na autocomunicação e autorrepresentação. Esse cenário remete ao caráter educomunicativo das práticas construídas na mobilização estudantil em prol da educação pública.
Percepções sobre presença social em interações mediadas por dispositivos de comunicação móveis
Authors: Amparo Sobrinho José Bonifácio do , Ayres Marcel , Ribeiro José Carlos
Published: January 2019

Este artigo apresenta uma análise qualitativa sobre a percepção da Presença Social em interações mediadas por dispositivos móveis, tomando como foco principal de exploração as particularidades associadas à ausência ou diminuição de pistas não verbais (habitualmente ocorridas nesta modalidade de mediação). Os dados são provenientes de uma pesquisa realizada com 120 jovens universitários de seis cidades brasileiras. Os relatos dos respondentes apontaram, em geral, dificuldades na percepção da presença social devido à sobreposição de demandas e expectativas sociais derivadas de duas modalidades interacionais: via dispositivos móveis e face a face.
Utopia no fim do homem soviético
Authors: Sena Cardoso Ercio do Carmo , Santos José Milton
Published: January 2019

A proposta deste estudo é de uma análise da utopia na obra O fim do homem soviético. No artigo, são apresentadas distintas recomendações sobre o livro da escritora e jornalista Svetlana Aleksiévich, relacionando-o, principalmente, com aspectos do jornalismo literário. Escrito a partir de relatos e depoimentos de pessoas comuns, o trabalho da autora é analisado por meio de falas cotidianas que abordam o fim do socialismo na União Soviética. A autora busca a percepção da grande narrativa sobre a construção socialista na visão das pessoas ordinárias, afetadas diretamente por esse período. Seis categorias de análise são definidas e excertos da obra, considerados mais representativos, são destacados na análise dos autores.
Análise dos modelos colaborativos de softwares para edição de ontologias por meio do Modelo 4C de Colaboração
Authors: Silva Marcel Ferrante , Martins Dalton Lopes , Santana Douglas Veronez , Siqueira Joyce
Published: January 2019

Esta pesquisa objetiva apresentar os modelos de colaboração de seis softwares editores de ontologia: MusicBrainz, OntoWiki, Semantic MediaWiki, Tainacan Ontology, WebProtégé e Wikidata, e relacionar as ferramentas para colaboração disponíveis classificando-as de acordo com o Modelo 4C de Colaboração, que abrange a comunicação, coordenação e colaboração e cooperação. O resultado abrange diversas nuances em relação aos softwares, detalhando a participação em cada ‘C’ do Modelo, mas de forma geral, apresenta o WebProtégé com o maior número de quesitos de comunicação, enquanto o Tainacan Ontology possui o maior número de quesitos relacionados à coordenação e a colaboração e cooperação. O modelo de colaboração dos softwares é essencial para promover a interação, de forma a mediar as divergências e possibilitar efetiva colaboração, por isso, quanto mais completo, melhor é o serviço oferecido, assim, espera-se que estes resultados sirvam como base para atualizações dos softwares existentes ou para criação de novos.
Memória Organizacional na Ciência da Informação: desvendando relações com o Conhecimento Organizacional
Authors: Feitoza Rayan Aramís de Brito , Sousa Laiana Ferreira de , Campos Ilka Maria Soares , Duarte Emeide Nóbrega
Published: January 2019

Este trabalho busca analisar os conceitos de Memória Organizacional por meio da produção científica publicada na Base de Dados de Periódicos em Ciência da Informação, com o intuito de entender suas relações com o Conhecimento Organizacional. Metodologicamente, caracteriza-se como uma pesquisa documental do tipo exploratória e descritiva com abordagem quali-quantitativa. Para análise e organização dos dados foi utilizada a análise de conteúdo enquanto método de procedimento, seguindo a técnica de análise temática, considerando: os autores que mais se destacaram na produção de pesquisas sobre a temática, distribuição de artigos de periódicos sobre Memória Organizacional por ano, periódicos indexados na base citada com publicações de artigos sobre o tema, principais palavras-chave abordadas pelos trabalhos analisados e, por último, a análise dos conceitos sobre Memória Organizacional para o entendimento de suas relações com Conhecimento Organizacional. Os resultados permitem inferir que houve um aumento no interesse por estudar a estrutura organizacional das empresas, evidenciando a necessidade de expandir as pesquisas envolvendo a cultura e memória das organizações. A pesquisa possibilitou verificar também que os conceitos de Memória Organizacional apresentam relações dialógicas com o Conhecimento Organizacional, permitindo concluir que possuem correlações nos sentidos metodológicos, conceituais e práticos.
Radiologic diagnosis of pulmonary metastases of uterine choriocarcinoma
Authors: Sudarkina A. V. , Dergilev A. P. , Chikinev Yu. V. , Drobyazgin E. A. , Kochura V. I. , Gorbunov N. A.
Published: January 2019

The article describes a rare case of metastatic pulmonary choriocarcinoma manifested with hemoptysis. Obstacles and pitfalls of the diagnosis of uterine choriocarcinoma with atypical manifestation were discussed. The patterns of pulmonary metastases of uterine choriocarcinoma and contribution of cross-sectional imaging modalities to diagnostic work-up were described. For the first time diffusion weighted magnetic resonance imaging of the chest was used for the follow-up examination and diagnosis of the recurrence of the disease.

This case is of interest due to unusual clinical and radiological presentation of uterine choriocarcinoma. The article is aimed to radiologists to be familiar with this disease to provide its early diagnosis and timely treatment.
Designing an Industrial Policy for Developing Countries: A New Approach
Authors: Haeri Ali , Arabmazar Abbas
Published: January 2019

In this study, the prevalent methodology for design of the industrial policy in developing countries was critically assessed, and it was shown that the mechanism and content of classical method is fundamentally contradictory to the goals and components of the endogenous growth theories. This study, by proposing a new approach, along settling Schumpeter's economic growth theory as a policy framework, designed the process of entering, analyzing and processing data as the mechanism of the industrial policy in order to provide "theoretical consistency" and "technical and Statistical requirements" for targeting the growth stimulant factor effectively.
Delineation of Cocoa Agroforests Using Multi-Season Sentinel-1 SAR Images: Low Grey Level Range Reduces Uncertainties in GLCM Texture-Based Mapping
Authors: Numbisi Frederick N. , Van Coillie Frieke M. B. , De Wulf Robert
Published: January 2019

Delineating the cropping area of cocoa agroforests is a major challenge for quantifying the contribution of the land use expansion to tropical deforestation. Discriminating cocoa agroforests from tropical transition forests using multi-spectral optical images is difficult due to a similarity in the spectral characteristics of their canopy; moreover, optical sensors are largely impeded by the frequent cloud cover in the tropics. This study explores multi-season Sentinel-1 C-band SAR image to discriminate cocoa agroforests from transition forests for a heterogeneous landscape in central Cameroon. We use an ensemble classifier, random forest, to average SAR image texture features of GLCM (Grey Level Co-occurrence Matrix) across seasons; next, we compare classification performance with results from RapidEye optical data. Moreover, we assess the performance of GLCM texture feature extraction at four different grey level quantization: 32bits, 8bits, 6bits, and 4bits. The classification overall accuracy (OA) of texture-based maps outperformed that from an optical image; the highest OA of 88.8% was recorded at 6bits grey level. This quantization level, in comparison to the initial 32bits in SAR images, reduced the class prediction error by 2.9%. Although this prediction gain may be large for the landscape area, the resultant thematic map reveals the decrease and fragmentation of forest cover by cocoa agroforests. According to our classification validation, the Shannon entropy (H) or uncertainty provides a reliable validation for class predictions and reveals detail inference for discriminating inherently heterogeneous vegetation categories. The texture-based classification achieved a reliable accuracy considering the heterogeneity of the landscape and vegetation classes.
An Intelligent and Secure Package Sensoring Logistics System Based on a Subliminal Channel
Authors: Chen Chin-Ling , Deng Yong-Yuan , Li Chun-Ta , Zhu Shunzhi
Published: January 2019

As e-commerce services and Internet technology have rapidly developed in recent years, many services and applications integrating these technologies can now be completed online. These commercial activities include online auctions, online ticketing and online payments. The client shops from the store online, andthe store delivers the goods to the client. The goods can be divided into digital products without entities, as well as actual entities. If it is a physical product, the store will deliver the package to the client through itslogistics. However, there have been many cases of switched goods purchased by clients in recent years. Earlier, some scholars proposed a security mechanism with a subliminal channel for E-cash and digital content. Only the sender and the receiver would know that the secret information was hidden in the signature. So the privacy of this subliminal message couldbe ensured. We apply this concept to the logistics environment to design secure logistics architecture with subliminal messages. The client can check the subliminal message of the received package, and know whether the package has been switched by malicious people. In addition, the proposed scheme also applies sensor technology;the client can check the GPS location, the temperature and humidity at any time during the delivery process. So intelligent logisticswouldthereby be achieved. This paper proposes an intelligent and secure package sensoring logistics system based on a subliminal channel. The proposed architecture uses the related mechanisms tosolve the problems of a logistics system, including how to achieve mutual authentication, data integrity, anti-switch package, package location and status tracing, resisting replay attacks, forward and backward secrecy, and non-repudiation issues.
Para una nueva edición de las Poesías de Miguel de Unamuno: La torre de Monterrey a la luz de la luna
Authors: SCOTTO DI CARLO Assunta C.
Published: January 2019

Este artículo se propone presentar la edición filológica de una de las composiciones de Poesías –la primera colección de poemas publicada por Miguel de Unamuno en 1907–; en concreto la que lleva por título La torre de Monterrey a la luz de la luna. La elección de esta obra fue dictada por varios factores, el principal la variedad de materiales disponibles, hecho que la dota de interés para la construcción del aparato. En la última parte del artículo se ofrece un breve comentario al texto y algunas consideraciones sobre el uso del aparato.
Luis Martín-Santos ante la censura: las vicisitudes editoriales de Tiempo de silencio
Authors: BRESADOLA Andrea
Published: January 2019

Se estudia la relación de Luis Martín-Santos con la censura franquista a través del examen de los documentos relativos a su producción literaria y científica conservados en el Archivo General de la Administración. El análisis se centra especialmente en las vicisitudes editoriales de Tiempo de silencio: se hacen públicos por primera vez todos los informes de los censores y las cartas que cruzaron la editorial y los órganos estatales. Con estos expedientes se puede trazar la trayectoria de la novela y dilucidar las razones que llevaron a las relevantes supresiones de orden moral de la primera edición y a la parcial restauración de las tachaduras en la segunda. El descubrimiento del manuscrito original ha permitido también el cotejo con la princeps, que ha explicitado en primer lugar un constante proceso de normalización lingüística. Además, se ha destacado la presencia de variantes y de alguna lección errónea tanto en la primera edición como en la “definitiva” de 1980.
Antisemitismo canino en las Coplas del perro de Alba
Authors: MARTÍN Adrienne L.
Published: January 2019

El objetivo principal de este trabajo es abordar el estudio de las Coplas del perro de Alba, un texto olvidado hasta el momento por la mayor parte de la crítica, en relación con su cariz marcadamente antisemitista, el cual permite relacionarlo con numerosos textos posteriores de nuestra literatura. El alejamiento de los topoi comunes en este tipo de sátiras, la incorporación de la figura del can como principal enemigo de los judíos y la dignificación casi heroica del mismo, hacen de este texto, a pesar de su escaso mérito estético-literario, un testimonio de primera fila de las problemáticas interacciones sociales de la España del momento y, tal vez, también de la época moderna.
Airway management in patients with oral cavity or oropharyngeal cancer: A single-institution retrospective study
Authors: Zheng Gang , Feng Lei , Lewis Carol M
Published: January 2019

Background: Oral cavity and oropharyngeal cancer impose significant threat to airway management. Head and neck radiotherapy (HNRT) may further increase the difficulty of tracheal intubation.
Methods: The tracheal intubation status between the two patient groups (treated vs. untreated with HNRT) was compared. The t test was used to evaluate differences in continuous variables between the 2 groups. Fisher’s exact test or a chi-square test was used to test for associations between radiation status and patient characteristics that may be associated with difficult tracheal intubation. Odds ratio and its confidence interval were used to assess the effect of radiation status on intubation status.
Results: The data of 4011 patients were reviewed. The final cohort of 472 matched patients in age, sex and body mass index consisted of 236 patients who had HNRT before surgery and 236 who had upfront surgery without HNRT. The percentage of patients who had restricted neck range of motion in the HNRT group was significantly higher than in the control group (22.3% vs. 11.0%; P = 0.001). The proportion of patients with trismus (P = 0.11) and with difficult tracheal intubation (p = 0.73) did not differ significantly between the 2 groups. 12.7% patients in the study had difficult tracheal intubation. Patients who had mallampati scores of 3 or 4 had significantly higher rate of difficult tracheal intubation than did patients with mallampati scores of 1 or 2 (17.8% vs. 8.7%; p = 0.004). Multivariate logistic regression model showed no difference between HNRT and intubation status after adjusting neck range of motion and mallampati score (OR=0.91, 95% CI: 0.510 to1.612).
Conclusions: Patients treated with HNRT was not associated with additional risk of difficult tracheal intubation. Mallampati score may be a sensitive measurement for difficult tracheal intubation in patients with oral cavity or oropharyngeal cancer.
Keywords: Radiotherapy, cancer, trismus, upper aerodigestive track, airway.
Paraneoplastic neuromyelitis optica spectrum disorder associated with breast cancer: a case report and literature review
Authors: Yuan Junliang , Jia Zejin , Qin Wei , Hu Wenli
Published: January 2019

Background: Neuromyelitis optica spectrum disorder (NMOSD) is an astrocytopathy with demyelinating lesions caused by aquaporin 4 (AQP4) antibodies. Although most commonly an idiopathic autoimmune condition, NMOSD may also occur as a paraneoplastic syndrome in rare instances.
Case presentation: Herein, we report a rare case of a 60-year-old woman with paraneoplastic NMOSD associated with breast cancer.
Conclusions: Our findings increase the recognition that NMOSD may present as a paraneoplastic neurological syndrome associated with breast cancer. Our case also raises awareness of an important complication of neurological complications of breast cancer. Early diagnosis of paraneoplastic NMOSD may be imperative for a better prognosis.
Keywords: Neuromyelitis optica spectrum disorder, paraneoplastic syndrome, breast cancer.
IL-10 Promotes Glioma Cell Growth and Invasion via Upregulation of KPNA2 In vitro
Authors: Zhang Zihao , Huang Xiaoming , Li Jie , Fan Haitao , Yang Fan , Zhang Rui , Yang Yihang , Feng Shaobin , He Dong , Sun Wei , Xin Tao
Published: January 2019

Background: Glioma is one of the leading causes of death worldwide with high incidence, recurrence and mortality. IL-10 is a cytokine with dual function in many types of tumors. Although IL-10 is overexpressed and promotes tumor progression in human primary brain tumor, the mechanisms are largely unknown.
Methods: Glioma cells were treated with different dosages of IL-10. The cell growth was detected by CCK8, and the invasion was measured by Transwell. The relative expression of mRNAs was detected by Quantitative real-time PCR (q-PCR).
Results: We found that IL-10 treatment significantly enhanced glioma cell growth and invasion. And KPNA2 was significantly upregulated after treatment with IL-10. By performing knockdown experiments, we found that the glioma cell growth and invasion were significantly declined.
Conclusions: The results indicated that knockdown of KPNA2 significantly inhibited the growth and invasion of glioma cells. And IL-10 promotes glioma progression via upregulation of KPNA2. This study will be of important significance and provides a potential target for treatment of patients with glioma.
Keywords: Cell growth, cell invasion, glioma, IL-10, KPNA2.
Vision status of children aged 7 - 15 years referred from school vision screening in Norway during 2003 - 2013: a retrospective study
Authors: Falkenberg Helle K , Langaas Trine , Svarverud Ellen
Published: January 2019

Background: Undetected vision problems are an important cause of reduced academic achievement, performance in everyday life and self-esteem. This receives little attention in national health care services even though most of these vision problems are easily correctable. Data on how many schoolchildren are affected are limited. This study aims to increase the knowledge of vision status in primary and secondary school children by retrospectively describing the vision status of children referred from vision screening during the ten year period 2003 – 2013.
Methods: Of 1126 (15 %) children referred to the university eye clinic, all 782 who attended were included. Patient records were reviewed with regards to symptoms, refractive error, best corrected logMAR visual acuity (BCVA), binocular vision, ocular health and management outcomes.
Results: Previously undetected vision problems were confirmed in 650 (83 %) of the children. The most frequent outcomes were glasses (346) or follow up (209), but types of treatment modalities varied with age. Mean refractive errors were hyperopic for all age groups, but reduced with age (ANOVA, p < .001). Refractive errors did not change across the decade (linear regression, all p > .05). Mean BCVAs were better than 0.0 and improved with age (ANOVA, p < .001). The most prevalent symptoms were headaches (171), near vision problems (149), and reduced distance vision (107).
Conclusions: The vision screening identified children with previously undetected visual problems. There was no change in refractive errors for either age group over the decade. Importantly, most of the problems were solved with glasses. Types of visual problems varied with age, which stresses the importance of regular eye examinations, and raised awareness among parents and teaching staff.
Keywords: Health care services, children, vision examination, visual status, refractive errors.
A comparison between a white LED confocal imaging system and a conventional flash fundus camera using chromaticity analysis
Authors: Sarao Valentina , Veritti Daniele , Borrelli Enrico , Sadda SriniVas R , Poletti Enea , Lanzetta Paolo
Published: January 2019

BACKGROUND: Conventional flash fundus camera captures color images that are over-saturated in the red channel, producing a retinal picture that looks washed-out and uniform. A white LED confocal device was recently introduced to provide a neutral-looking retinal image. With this study we aimed to evaluate the color rendering properties of the white LED confocal system and to compare it to a conventional flash fundus camera through the use of chromaticity analysis.
METHODS: A fully automated white LED confocal device (Eidon, Centervue, Padova, Italy) was used to capture fundus images from healthy volunteers and patients with retinal diseases. The same pictures were acquired with a flash fundus camera (Triton, Topcon Corporation, Tokyo, Japan). All color images were evaluated with respect to the chromaticity. Color analysis was performed according to the image color signature. Color signature of an image was defined as the distribution of its pixels in the rgb chromaticity space. The descriptors used for the analysis are the average and variability of the barycenter positions, the average of the variability and the number of unique colors (NUC) of all signatures.
RESULTS: Two hundred thirty-three color fundus photographs were acquired with each retinal camera. The images acquired by confocal white LED device demonstrated an average barycenter position (rgb = [0.448, 0.328, 0.224]) closer to the center of the chromaticity space, while conventional fundus camera provides images with a clear shift toward red at the expense of the blue and green (rgb = [0.574, 0.278, 0.148] (p<0.001). The variability of the barycenter positions was higher in white LED confocal system than in conventional flash fundus camera. The average variability of the distributions was higher (0.003 ± 0.007, p<0.001) in the Eidon images compared to Topcon camera, indicating a greater richness of color. The NUC percentage was higher for white LED confocal device than for conventional flash fundus camera (0.071% versus 0.025%, p<0.001).
CONCLUSIONS: Confocal white LED system provides well-balanced color images with a wider richness of color content compared to conventional flash fundus camera. The overall higher chromaticity of Eidon device may provide benefits in terms of discriminative power and diagnostic accuracy.
KEYWORDS: Chromaticity; Confocal white LED system; conventional flash fundus camera; Eidon; Topcon.
A Network-Based Cancer Drug Discovery: From Integrated Multi-Omics Approaches to Precision Medicine
Authors: Turanli Beste , Karagoz Kubra , Gulfidan Gizem , Sinha Raghu , Mardinoglu Adil , Arga Kazim Yalcin
Published: January 2019

A complex framework of interacting partners including genetic, proteomic, and metabolic networks
that cooperate to mediate specific functional phenotypes drives human biological processes. Recent technological
and analytical advances in “omic” sciences allow the identification and elucidation of reprogramming biological
functions in response to perturbations in cells and tissues. To understand such a complex system, biological networks
are generated to reduce the complexity into relatively simple models, and the integration of these molecular
networks from different perspectives is implemented for a holistic interpretation of the entire system. Ultimately,
network-based methods will effectively facilitate the development and improvement of precision medicine
by directing therapies based on the underlying biology of a given patient’s disease.

The goal of precision medicine is to identify novel therapeutic strategies that can be optimized for each disease
type or each patient based on the underlying genetic, environmental, and lifestyle factors. Pharmaco-omics analyses
based on an integration of pharmacology and various “omics” data types can be employed to develop effective
treatment strategies using particular drugs and doses that are tailored to each individual.

In the current review, we first present the core elements of network-based systems biology in the context of
pharmaco-omics followed by integration of multi-omics data using various biological networks. Next, we provide
an opening into precise medicine and drug targeting based on network approaches. Lastly, we review the current
significant efforts as well as the accomplishments and limitations in precise drug targeting with the utility of
network-based guided drug discovery methods for effective treatment of breast cancer.
Los insectos escama (Hemiptera: Coccomorpha) de raíces de café (Coffea arabica L.) en Colombia, con registros de hormigas (Hymenoptera: Formicidae) en asociación
Authors: Caballero Alejandro , Ramos-Portilla Andrea Amalia , Suárez-González Diana , Serna Francisco , Gil Zulma Nancy , Benavides Pablo
Published: January 2019

Los insectos escama asociados a raíces son de interés económico en cultivos como el café. Aunque existen desarrollos notables en el conocimiento sobre la taxonomía alfa de tales insectos, se requiere más información sobre su diversidad. El objetivo de este trabajo fue actualizar la lista de especies de insectos escama huéspedes en raíces de café en Colombia, así como reconocer sus hormigas trofobióticas. Se recolectaron 541 muestras en nueve departamentos de Colombia; se analizaron 4.762 especímenes de insectos escama y 450 hormigas. Los coccomorfos se prepararon en láminas para microscopía y las hormigas, en doble montaje en seco. Asimismo, se examinaron 250 muestras de escamas conservadas en siete colecciones entomológicos de Colombia. Por último, se revisó la literatura relacionada con registros previos de escamas en café para el país. La presente investigación provee una lista actualizada de especies de insectos escama para el cultivo en el país, incluida su distribución geográfica y hormigas asociadas. Se actualiza la lista de insectos escama asociadas a raíces de café a 61 especies, 52 de ellas obtenidas a partir de las muestras analizadas y nueve por registros de literatura; se hacen 20 nuevos registros de asociación con café y 15 nuevos registros para Colombia. Las especies con mayor presencia en el cultivo fueron Puto barberi, Geococcus coffeae, complejo Dysmicoccus texensis, Rhizoecus colombiensis y Pseudococcus elisae. Además, se obtuvieron 32 morfoespecies de hormigas, de las cuales 30 se conocen en relaciones trofobíoticas facultativas con hemípteros, y dos del género Acropyga en trofoforesia.
Feedback on Physical Activity Through a Wearable Device Connected to a Mobile Phone App in Patients With Metabolic Syndrome: Pilot Study (Preprint)
Authors: Huh Up , Tak Young Jin , Song Seunghwan , Chung Sung Woon , Sung Sang Min , Lee Chung Won , Bae Miju , Ahn Hyo Young
Published: January 2019

BACKGROUND

Little is known of the effect of wearable devices on metabolic impairments in clinical settings. We hypothesized that a wearable device that can monitor and provide feedback on physical activity may help resolve metabolic syndrome.

OBJECTIVE

This study aimed to examine the objective effects of the use of these devices on metabolic syndrome resolution.

METHODS

Patients diagnosed with metabolic syndrome were recruited. Participants were prescribed regular walking using a wearable device (Coffee WALKIE +Dv.3, GC Healthcare CI, Korea) on their wrist for 12 weeks. Participants received self-feedback on the amount of their exercise through an app on their mobile phone. The information on physical activities of the participants was uploaded automatically to a website. Thus, a trained nurse could provide individuals with feedback regarding the physical activity via telephone consultation on alternate weeks. Blood pressure (BP), body composition, fasting plasma glucose, and lipid profiles were recorded. The primary outcome was metabolic syndrome resolution. The secondary outcome was an improvement in the components of metabolic impairment.

RESULTS

Of the 53 participants recruited, 20 participants with a median age of 46 (range 36-50) years completed the trial. There was no significant difference in the amount of calorie expenditure at weeks 4, 8, and 12. After 12 weeks, metabolic syndrome was resolved in 9 of 20 participants (45%), and the mean number of metabolic impairment components per person decreased from 3.4 to 2.9. Particularly, the mean systolic and diastolic BP decreased from mean 136.6 (SD 18.5) mm Hg to mean 127.4 (SD 19.5) mm Hg and from mean 84.0 (SD 8.1) mm Hg to mean 77.4 (SD 14.4) mm Hg (both P=.02), respectively.

CONCLUSIONS

This study found that a 12-week intervention via feedback, based on a wearable physical activity monitor, helped metabolic syndrome patients to be more engaged in regular walking and it improved impaired metabolic components, especially in BP. However, some practical challenges regarding patients’ adherence and sustained engagement were observed.
Integrating Taxonomies Into Theory-Based Digital Health Interventions for Behavior Change: A Holistic Framework (Preprint)
Authors: Wang Yunlong , Fadhil Ahmed , Lange Jan-Philipp , Reiterer Harald
Published: January 2019

UNSTRUCTURED

Digital health interventions (DHIs) have been emerging in the last decade. Due to their interdisciplinary nature, DHIs are guided and influenced by theories (eg, behavioral theories, behavior change technologies, and persuasive technology) from different research communities. However, DHIs are always coded using various taxonomies and reported in insufficient perspectives. This inconsistency and incomprehensiveness will cause difficulty in conducting systematic reviews and sharing contributions among communities. Therefore, based on existing related work, we propose a holistic framework that embeds behavioral theories, behavior change technique taxonomy, and persuasive system design principles. Including four development steps, two toolboxes, and one workflow, our framework aims to guide DHI developers to design, evaluate, and report their work in a formative and comprehensive way.