bluuebunny/crossref_metadata_2025 huggingface dataset:
Influencia de actividades motrices finas para desarrollar el agarre del lápiz en educación inicial
Authors: Alcívar Mata Mirian Alexandra , Paredez Barcia Kenia Gabriela , Carrillo Pilozo Ginger Isabel , Peñaherrera Villafuerte Karina Rossana , Ramos Peñafiel Diana Carolina , Álvarez Castro Germania Janeth
Published: June 2024

La presente investigación tuvo como objetivo analizar la influencia de las actividades motrices finas en el desarrollo del agarre del lápiz en niños de Educación Inicial. Para ello, se realizó una revisión bibliográfica para identificar las prácticas pedagógicas sobre motricidad fina, se aplicó una evaluación estandarizada a los niños para evaluar el progreso del agarre del lápiz y se diseñaron actividades motrices finas para mejorar el agarre del lápiz. Los resultados mostraron que las actividades motrices finas tienen una influencia significativa en el desarrollo del agarre del lápiz en niños de educación inicial. Se evidenció que los niños que participaron en las actividades motrices finas diseñadas para el estudio mostraron una mejora significativa en el agarre del lápiz en comparación con el grupo control. En conclusión, las actividades motrices finas son un factor importante para el desarrollo del agarre del lápiz en niños de educación inicial. Es importante que los docentes implementen actividades motrices finas en sus aulas para ayudar a los niños a desarrollar un agarre del lápiz adecuado.
Percepción sobre los servicios educativos en instituciones públicas
Authors: Cerezo Vera Juana Verónica , Montalván Castillo Sonia Cristiana , Sánchez Ordóñez Martha Yajaira , López Bohórquez Sarina Daidamia , García Rubio Mauricio Sebastián , Chela Coyago Oswaldo Fabián
Published: June 2024

El trabajo de investigación tiene como objetivo analizar el nivel de satisfacción de los actores educativos respecto de la percepción que tienen sobre la calidad del servicio educativo que ofrecen las instituciones educativas. La metodología de la investigación se basa en un enfoque cuantitativo mediante un diseño transversal, la investigación descriptiva. La muestra de estudio se conforma de 150 docentes, 150 estudiantes y 150 padres de tres instituciones educativas públicas de la ciudad de Santo Domingo. Se aplicó una encuesta para abordar las dimensiones de la gestión escolar y se aplicó tres escalas: insatisfecho, medianamente satisfecho, insatisfecho. La técnica de análisis de datos es la estadística descriptiva por medio de SPSS. Los resultados muestran un 74% de docentes satisfechos, un 67,3% de estudiantes que dicen estar satisfechos y un 55,3% de padres de familia satisfechos. En este sentido, se demuestra que existe una satisfacción global alta de aceptación de los servicios educativos.
Некоторые замечания о биологии и проблемах диагностики красного томатного паутинного клеща Tetranychus evansi Baker & Pritchard, 1960 (Acari: Prostigmata: Tetranychidae)
Authors: Камаев И.О.
Published: June 2024

Приводятся актуальные сведения о распространении, новая информация о растениях-хозяевах и вопросах диагностики красного томатного паутинного клеща (Tetranychus evansi) – карантинного объекта Единого перечня ЕАЭС. В статье даны оригинальные иллюстрации симптомов повреждения растений-хозяев и диагностических признаков вредителя.
Идентификация грибов рода Monilinia при фитосанитарной диагностике
Authors: Шухин Д.И.
Published: June 2024

В статье приведены традиционные, а также современные методы идентификации возбудителей монилиозов плодовых культур – грибов рода Monilinia, используемые при фитосанитарной диагностике, такие как классическая ПЦР и ПЦР в реальном времени, а также мультиплексная ПЦР. Описан новый метод масс-спектрометрии MALDI-ToF MS, а также методы выявления патогенов при латентной инфекции.
О географических популяциях табачной белокрылки Bemisia tabaci Genn.
Authors: Ушкова М.В. , Колесникова Е.В. , Ершова Н.И.
Published: June 2024

В работе представлен обзор литературных данных по географическим популяциям табачной белокрылки Bemisia tabaci Genn. по результатам молекулярной диагностики. Проведено исследование морфологической изменчивости биотипов табачной белокрылки. Настоящая работа может быть использована специалистами лабораторий, осуществляющих исследования в области карантина растений, в качестве справочной информации, а также может быть использована для мониторинга популяций табачной белокрылки.
О некоторых видах грибов в насаждениях черники обыкновенной на территории Республики Карелия и Архангельской области
Authors: Копина М.Б. , Сурина Т.А. , Уварова Д.А.
Published: June 2024

В статье представлены результаты изучения фитопатологического состояния естественных насаждений на севере европейской части России: отдельные районы Республики Карелия и Большой Соловецкий остров (Архангельская область). Даны описания некарантинных видов грибов, выделенных с растений черники обыкновенной. Приводятся данные видовой идентификации микромицетов по морфологическим признакам и с помощью расшифровки нуклеотидных последовательностей.
Navigating English Learning Challenges During the Pandemic: Insights from the National Learning Camp and Subsequent Performance Trends
Authors: Sosmeńa Lizel
Published: June 2024

The study aimed to investigate the correlation between students' performance in English 8, the challenges they faced in learning English during the pandemic, and their performance after the National Learning Camp. The researcher utilized descriptive-correlational and comparative designs and employed the systematic sampling technique in identifying the 240 respondents from the Grades 9 learners of Dumaguete City National High School. The researcher used validated questionnaires and employed percentage, weighted mean, and multiple regression analysis in treating the data. The study revealed that the National Learning Camp (NLC) has shown a positive impact on the students' performance in English 8. The students' performance improved after the NLC, with a statistically significant difference. Additionally, the data revealed that the challenges faced by students in terms of access, equity, quality, resiliency, and well-being are moderate. There is a significant relationship between the extent of students' challenges in learning English during the pandemic in terms of access, suggesting that these issues may have influenced their performance.
Mathematics Teachers’ Strategies for Improving Students’ Critical Thinking Skills
Authors: Cayud-ong Franklin , Futalan Maria Chona
Published: June 2024

This study aimed to determine mathematics teachers’ extent of utilization of strategies in terms of asking questions, analyzing situations, interpretation of data, and panel discussions in improving students’ critical thinking skills. It also examined the level of critical thinking skills of students as well as its relationship to the enumerated strategies. The researchers utilized the descriptive-correlation design and employed the systematic sampling technique in identifying the 320 junior high school respondents from grade 7 to grade 10 of the school year 2023 to 2024 of the four secondary schools of Lazi District in the Division of Siquijor. The researchers used adapted and validated questionnaires and employed mean and Spearman Rank Order Correlation for the data treatment. The findings revealed that the teachers’ extent of utilization in terms of the following strategies is “high”: (a) asking questions, (b) analyzing situations, (c) interpreting data, and (d) panel discussion. It was also found that the level of students’ critical thinking skills is “high”. The data further indicated that the mentioned strategies are significantly related to students’ level of critical thinking skills. These findings implicate that teachers are able to employ teaching strategies that are beneficial for improving the critical thinking skills of the students in the field of Mathematics. By incorporating these strategies, the teachers are creating an engaging and intellectually stimulating learning environment.
APPLYING SIX SIGMA TO IMPROVE THE DEFECT RATE OF ELECTRONIC COMPONENTS: A SIX SIGMA CASE STUDY
Authors: Fan Ping-Hsin
Published: June 2024

This study aimed to improve the touch responses of electronic products. The improvement method was based on six sigma improvement steps. Product quality was improved using define, measure, analyse, improve, control (DMAIC) and statistical quality control methods to reduce the cost and waste of defective products. The project identified five critical processes from the manufacturing process and eight critical to characteristics (CTCs). Then CTCs were identified through the critical to characteristic diagram. The root causes were verified using the experimental plan method, scatter diagram, and double ratio test. This study identified three root causes, namely ‘poor reed touch value’, ‘base cavity width’, and ‘jig precision’. The last two causes were evaluated, and countermeasures were taken to ‘change the size of the base cavity’, ‘change the design of the assembly jig’, and ‘change the process of the assembly jig’. The target rate of the overall product defect rate reached 127%.
DEVELOPMENT OF A SUSTAINABLE LEAN COMPETITIVE STRATEGY IN A WATER PUMP COMPANY
Authors: Saraswati Docki , Sari Emelia , Sekarwardhani Gebyar
Published: June 2024

The manufacturing industry is currently experiencing a shift towards sustainability-driven practices and principles. Company X is one of those that want to improve their competitiveness in the manufacturing industry by implementing sustainability. However, this company experiences obstacles in its production process because production targets still need to be achieved owing to product defects that average 8.97%. This study used the sustainable lean manufacturing approach to help the company to achieve more competitive goals by reducing waste and pollution and creating more efficient production processes. The tools used in this research were process activity mapping (PAM), sustainable value stream mapping (SVSM), and the sustainability index (SI). Based on calculations with sustainability indicators, the company’s SI results amounted to 183%. The pProposed improvements were given to improve the company’s efficiency and to reduce its SI. After repairs had been made, the SI value was reduced to 118%. With the improvement in that value, production efficiency has also improved: the process cycle efficiency (PCE) value has become 90.49%, which means that the company’s production process has become more efficient.
IMPACT OF RURAL ROAD PROVISION ON EMPLOYMENT
Authors: Pienaar WJ (Wessel)
Published: June 2024

This article focuses on the impact of rural road provision on the macroeconomic objective of full employment. It deals with the extent to which roads act as direct generators of jobs during their construction and service periods, and the ways in which effective roads could indirectly stimulate employment opportunities quantitatively and, from a skills perspective, qualitatively. The economic impact analysis (ECIA) of road provision indicates the typical worker–hour requirements for the approximate estimation of employment needs. These estimates can be used whenever detailed estimates are not yet available. The estimates are provided for the construction and operation of (1) basic rural road segments, (2) bridges and viaducts, and (3) intersections, roundabouts (traffic circles), and interchanges. Where road projects contain other physical components, such as tunnels and toll plazas, the former three groups of employment rates could be used in combination with worker–hour estimates for the construction and maintenance of tunnels and toll-related components.
DEVELOPING A VALUE ENGINEERING MODEL FOR A STATE-OWNED ENTERPRISE
Authors: Sewdayal Sudeish , Pellissier Rene
Published: June 2024

In this study, a value engineering model for state-owned enterprises was developed using a mixed-method approach, focusing on a South African state-owned enterprise. Key findings highlighted that strong management support, a supportive value engineering culture, an effective value engineering methodology, and an efficient value engineering team are vital enablers for successful value engineering implementation in state-owned enterprises. The study further emphasised the importance of recognising differences between state-owned enterprises and private organisations, as they require tailored value engineering approaches. In addition, the research explored factors influencing value engineering success, identified state-owned enterprise specific barriers, and provided recommendations. These findings offer unique insights into state-owned enterprises, aiding decision-makers, managers, and practitioners. Applying the model and recommendations can enhance state-owned enterprise performance, efficiency, and value realisation.
Transformation of the caryatid motif from Forum Augusti in urban ensembles of Campania and Roman Spain. Semantics, stylistics and iconography
Authors: Shadrina Sofia Aleksandrovna
Published: June 2024

The object of research in this article is the motif of caryatids in the decoration of the Forum of Augustus. Along with other elements, it is repeated in the ensembles of the cities of Roman Spain and region of Campania. It is believed that the August Forum in its decorative program broadcasts the most important ideological markers of the Early Empire era. In particular, the caryatids decorating the attic of the portico are reduced replicas of the famous figures of the Erechtheion. Such a reference is connected with the glorification of Rome's power over Greece in the reproduction of its figurative system. The subject of the study was the process of transformation that occurs with the motif of caryatids in non-classical ensembles. Following the iconographic, stylistic and semantic changes in the caryatid motif in the ensembles of the cities of August Emerita, Tarracon and Puteola, the author suggests possible causes and options for the transformation of these decorative elements. The article focuses on the possible causes of such a transformation, and also attempts to clarify the concept of the "Forum Augusti model", which is found in the research literature in various meanings and variants, through the analysis of a single element. The lack of a single definition of this phenomenon makes it possible to infinitely expand the range of monuments that could be created in imitation of the metropolitan prototype. The author of the article does not support this position, focusing on a few ensembles in which not only the same iconographic schemes occur, but also the logic of the decorative system is preserved. As a result of the research, it was possible to clarify the concept of the Forum Augusti model, which implies not so much the reproduction of the iconography and stylistics of the original.
Building Semantic Segmentation Using UNet Convolutional Network on SpaceNet Public Data Sets for Monitoring Surrounding Area of Chan Chan (Peru)
Authors: Chicchon Miguel , Malinverni Eva Savina , Sanità Marsia , Pierdicca Roberto , Colosi Francesca , Trujillo Francisco James León
Published: June 2024

The amount of damage to cultural heritage sites is increasing rapidly every year. This is due to inadequate heritage management and uncontrolled urban growth as well as unpredictable seismic and atmospheric events that manifest themselves in a continuously deteriorating ecosystem. Thus, applications of artificial intelligence (AI) in remote-sensing (RS) techniques (machine-learning and deep-learning algorithms) for monitoring archaeological sites have increased in recent years. This research involves the surrounding area of the archaeological site of Chan Chan in Peru in particular. An approach that is based on the use of AI algorithms for building footprint segmentation and changedetection analysis by means of RS images is proposed. It involves a UNet convolutional network based on an EfficientNet B0 to B7 encoder. The network was trained on two public data sets from SpaceNet that were based on WV2 and WV3 satellite images: SpaceNet V1 (Rio), and SpaceNet V2 (Shanghai). In the pre-processing phase, the images from the two data sets have been equalized in order to improve their quality and avoid overfitting. The building segmentation has been performed on HRV images of the study area that were downloaded from Google Earth Pro. The value that was achieved in the IoU metric was around 70% in both experiments. The purpose of this proposed methodology is to assist scientists in drafting monitoring and conservation protocols based on already-recorded data in order to prevent future disasters and hazards.
TAK1-mediated phosphorylation of PLCE1 represses PIP2 hydrolysis to impede esophageal squamous cancer metastasis
Authors: Ju Qianqian , Sheng Wenjing , Zhang Meichen , Chen Jing , Wu Liucheng , Liu Xiaoyu , Fang Wentao , Shi Hui , Sun Cheng
Published: June 2024

TAK1 is a serine/threonine protein kinase that is a key regulator in a wide variety of cellular processes. However, the functions and mechanisms involved in cancer metastasis are still not well understood. Here, we found that TAK1 knockdown promoted esophageal squamous cancer cell (ESCC) migration and invasion, whereas TAK1 overexpression resulted in the opposite outcome. These
in vitro
findings were recapitulated
in vivo
in a xenograft metastatic mouse model. Mechanistically, co-immunoprecipitation and mass spectrometry demonstrated that TAK1 interacted with phospholipase C epsilon 1 (PLCE1), and phosphorylated PLCE1 at serine 1060 (S1060). Functional studies revealed that phosphorylation at S1060 in PLCE1 resulted in decreased enzyme activity, leading to the repression of PIP2 hydrolysis. As a result, the degradation products of PIP2 including diacylglycerol (DAG) and inositol IP3 were reduced, which thereby suppressed signal transduction in the axis of PKC/GSK-3β/β-Catenin. Consequently, expression of cancer metastasis-related genes was impeded by TAK1. Overall, our data indicate that TAK1 plays a negative role in ESCC metastasis, which depends on the TAK1 induced phosphorylation of PLCE1 at S1060.
An Integrated Machine Learning Approach Delineates Entropy-mediated Conformational Modulation of α-synuclein by Small Molecule
Authors: Menon Sneha , Adhikari Subinoy , Mondal Jagannath
Published: June 2024

The mis-folding and aggregation of intrinsically disordered proteins (IDPs) such as
α
-synuclein (
α
S) underlie the pathogenesis of various neurodegenerative disorders. However, targeting
α
S with small molecules faces challenges due to its lack of defined ligand-binding pockets in its disordered structure. Here, we implement a deep artificial neural network based machine learning approach, which is able to statistically distinguish fuzzy ensemble of conformational substates of
α
S in neat water from those in aqueous fasudil (small molecule of interest) solution. In particular, the presence of fasudil in milieu either modulates pre-existing states of
α
S or gives rise to new conformational states of
α
S, akin to an ensemble-expansion mechanism. The ensembles display strong conformation-dependence in residue-wise interaction with the small molecule. A thermodynamic analysis indicates that small-molecule modulates the structural repertoire of
α
S via tuning protein backbone entropy, however keeping entropic ordering of surrounding solvent unperturbed. Together, this study sheds light on the intricate interplay between small molecules and IDPs, offering insights into entropic modulation and ensemble expansion as key biophysical mechanisms driving potential therapeutics.
Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a mouse model of head-and-neck cancer
Authors: Barr Jeffrey , Walz Austin , Restaino Anthony C. , Amit Moran , Barclay Sarah M. , Vichaya Elisabeth G. , Spanos William C. , Dantzer Robert , Talbot Sebastien , Vermeer Paola D.
Published: June 2024

Cancer patients often experience changes in mental health, prompting an exploration into whether nerves infiltrating tumors contribute to these alterations by impacting brain functions. Using a male mouse model for head and neck cancer, we utilized neuronal tracing techniques and show that tumor-infiltrating nerves indeed connect to distinct brain areas via the ipsilateral trigeminal ganglion. The activation of this neuronal circuitry led to behavioral alterations represented by decreased nest-building, increased latency to eat a cookie, and reduced wheel running. Tumor-infiltrating nociceptor neurons exhibited heightened activity, as indicated by increased calcium mobilization. Correspondingly, the specific brain regions receiving these neural projections showed elevated cFos and delta FosB expression in tumor-bearing mice, alongside markedly intensified calcium responses compared to non-tumor-bearing counterparts.The genetic elimination of nociceptor neurons in tumor-bearing mice led to decreased brain Fos expression and mitigated the behavioral alterations induced by the presence of the tumor. While analgesic treatment successfully restored behaviors involving oral movements to normalcy in tumor-bearing mice, it did not have a similar therapeutic effect on voluntary wheel running. This discrepancy points towards an intricate relationship, where pain is not the exclusive driver of such behavioral shifts. Unraveling the interaction between the tumor, infiltrating nerves, and the brain is pivotal to developing targeted interventions to alleviate the mental health burdens associated with cancer.
Quantitative intra-Golgi transport and organization data suggest the stable compartment nature of the Golgi
Authors: Tie Hieng Chiong , Wang Haiyun , Mahajan Divyanshu , Sun Xiuping , Chen Bing , Lu Lei
Published: June 2024

How the intra-Golgi secretory transport works remains a mystery. The cisternal progression and the stable compartment models have been proposed and are under debate. Classic cisternal progression model posits that both the intra-Golgi transport and Golgi exit of secretory cargos should occur at a constant velocity dictated by the cisternal progression; furthermore, COPI-mediated intra-Golgi retrograde transport is essential for maintaining the Golgi organization. Leveraging our recently developed Golgi imaging tools in nocodazole-induced Golgi ministacks, we found that the intra-Golgi transport velocity of a secretory cargo decreases during their transition from the cis to the trans-side of the Golgi, and different cargos exhibit distinct velocities even within the same cisternae. We observed a vast variation in the Golgi residence times of different cargos. Remarkably, truncation of the luminal domain causes the Golgi residence time of Tac — a standard transmembrane secretory cargo without intra-Golgi recycling signals — to extend from 16 minutes to a notable 3.4 hours. Additionally, when COPI-mediated intra-Golgi retrograde transport was inhibited by brefeldin A, we found that nocodazole-induced Golgi can remain stacked for over 30 - 60 minutes. Therefore, our findings challenge the classical cisternal progression model and suggest the stable compartment nature of the Golgi.
Chile 2021: populismo, cuestiones divisivas y el surgimiento de nuevos partidos en Facebook.
Authors: Peña Vicuña Percy , Fenoll Tomé Vicente , Romero Lizama Pamela
Published: June 2024

Las redes sociales proporcionan un espacio de comunicación digital que ayuda a difundir los mensajes de los actores políticos. Estudiar las estrategias utilizadas en estos canales puede ayudar a comprender las dinámicas sociales, especialmente aquellas relacionadas con los procesos electorales. Sin embargo, la mayor parte de las investigaciones sobre comunicación política se centran en las democracias del hemisferio norte. Para abordar esta brecha, este estudio examina las cuentas de Facebook de actores políticos chilenos durante la campaña de primera vuelta de las elecciones presidenciales de 2021. Desde una perspectiva cuantitativa, se analiza el contenido de las publicaciones de los siete principales partidos y candidatos. El corpus consta de una muestra de 909 publicaciones, codificadas manualmente según las categorías de tema, populismo y campañas negativas. A nivel de partidos se verifican diferencias en función de la ideología y la novedad institucional. Los resultados revelan el uso de retórica populista y temas divisivos por parte de formaciones políticas de oposición más nuevas y radicales. Sin embargo, el nivel de populismo durante esta campaña es inferior al detectado en otras regiones, y destaca la ausencia de ataques contra minorías étnicas o culturales. El análisis de la participación de los usuarios muestra que los partidos más nuevos generan más interacción con sus contenidos, ganando así mayor visibilidad. Estos hallazgos proporcionan una visión detallada de las estrategias de comunicación digital utilizadas durante la campaña electoral en Chile y contribuyen a ampliar el enfoque de los estudios de comunicación política al contexto sudamericano.
Formación y ámbito de los guionistas en Chile: análisis cualitativo a partir de entrevistasanálisis cualitativo a partir de entrevistas
Authors: Dittus Rubén , Elgueta Ruiz Álvaro
Published: June 2024

El artículo forma parte de un estudio más amplio que busca describir la enseñanza del guion audiovisual y la formación de guionistas en el Chile contemporáneo. Los resultados obtenidos provienen de la aplicación del método de entrevista semiestructurada a diez guionistas y docentes nacionales de reconocido prestigio en el área, comprobando la existencia de orientaciones estéticas, exigencias técnicas, relaciones con otros agentes del campo o formas de trabajar la escritura creativa en la preproducción escénica para cine y televisión. Se utilizaron cuestionarios abiertos cuyo objetivo fue generar, a partir de determinados núcleos temáticos predefinidos, la réplica de una conversación. A partir de estos núcleos generativos, las entrevistas se desarrollaron de manera flexible, con el objetivo de reforzar el carácter no estandarizado del instrumento, como es habitual en este tipo de ejercicios académicos. Lo que se presenta en esta síntesis son puntos en común y otros aspectos controvertidos. No tienen valor estadístico, sino que muestran el significado de la complejidad de los discursos generados.
Tratamientos de conservación de fábricas patrimoniales de albañilería de ladrillo cerámico en ambientes marinos urbanos
Authors: Urrutia Silva María Paz , Valenzuela Saavedra Matías , Garcés Alzamora Andrés
Published: June 2024

La ciudad de Valparaíso alberga una parte significativa del patrimonio industrial construido en albañilería de ladrillo cerámico. Sin embargo, las condiciones ambientales, incluyendo diversos agentes contaminantes, han provocado efectos adversos en las fábricas de ladrillo de principios del siglo XX. Tal es el caso del Muro Andes, una estructura ubicada en el entorno de la Tornamesa Barón, que forma parte del muro de cierre del antiguo complejo ferroviario y que ha experimentado graves compromisos tanto en su estructura como en su arquitectura debido al contexto en el que se encuentra.Este artículo presenta el proyecto de intervención del Muro Andes, llevado a cabo por el equipo de Asistencia Técnica de la Escuela de Arquitectura de la Pontificia Universidad Católica de Valparaíso durante el año 2020. El proyecto fue encargado por Metro Valparaíso, una filial del Grupo EFE, como parte de sus iniciativas para preservar y mantener en buen estado la infraestructura ferroviaria y su entorno.El desarrollo del proyecto se fundamentó en un estudio diagnóstico del estado de conservación mediante técnicas de análisis visual, fisicoquímico y físico-mecánico, con el fin de determinar tratamientos precisos frente a las patologías identificadas.
Dil Eğitiminde Çizgi Romanların Kullanımına Yönelik Bir Uygulama
Authors: Göçer Ali , Gürsoy Hasan Can
Published: June 2024

Çizgi romanlar 1920’li yıllardan bu yana eğitim ortamlarında eğitsel amaçlarla kullanılmaktadır. Bu durum yakın tarihimize kadar artan veya azalan ilgilerle devam etmiştir. Ancak yakın tarihten bugüne kadar geçen sürede yapılan çalışmalara bakıldığında çizgi romanlara yönelik bu ilginin sürekli olarak arttığı görülmektedir. Özellikle bilgisayar tabanlı uygulamalarla dijital çizgi roman üretebilme olanağı sayesinde süreç hızlanmış ve bu süreçte farklı bakış açıları kazanılmıştır. Bu çalışmada okuma, konuşma ve yazma eğitimine yönelik temel dil becerilerinin geliştirilmesinde çizgi romanların rolünü keşfetmek amaçlanmaktadır. Bu amaçla Türkçe öğretim programının rehberliği esas alınarak altıncı sınıf Türkçe ders kitabındaki metinlerle metin işleme süreçleri planlanmıştır. Planlanan metin işleme süreçlerinin aşamaları doğrultusunda Pixton programı kullanılarak okuma, konuşma ve yazma eğitimi kazanımlarına yönelik çizgi roman içerikli çalışma kâğıtları hazırlanmıştır. Kazanım odaklı hazırlanan bu çalışma kâğıtları ile altıncı sınıf öğrencilerine yönelik metin işleme süreçleri yürütülmüştür. Araştırma nitel yöntem çerçevesinde durum çalışması olarak desenlenmiştir. Görüşme, gözlem ve dokümanlar aracılığıyla toplanan veriler içerik analiziyle incelenmiştir. Yapılan analizler sonucunda elde edilen veriler neden sonuç ilişkisi çerçevesinde karşılaştırmalı olarak yorumlanmıştır. Çalışma sonuçları metin işleme süreçlerine yönelik hazırlanan çizgi romanların okuma, yazma ve konuşma eğitimiyle ilgili kazanımları edindirmede işlevsel bir materyal olduğunu ortaya koymaktadır. Metin işleme süreçlerinde çizgi roman kullanımıyla ilgili ortaya çıkan ve materyaller tasarlanırken göz önünde bulundurulması gereken bazı teknik ve baskı detayları da bu çalışmanın sonuçları arasında yer almaktadır. Çalışma sürecinde elde edilen veriler ve kazanılan bakış açıları doğrultusunda birtakım öneriler sunulmuştur.
СОВЕТСКИЙ ФАНТАСТ АЛЕКСАНДР БЕЛЯЕВ
Authors: Закутняя О.В.
Published: June 2024

Формальным поводом для того, чтобы написать об Александре Романовиче Беляеве, служит тот факт, что в конце 2023 г. журналу «Земля и Вселенная» была присуждена ежегодная премия имени Александра Беляева. Ее вручают в Пушкинском доме культуры, в том городе, где Александр Беляев жил несколько лет и где закончил свой земной путь страшной военной зимой 1941-1942 гг.
ПРИЛИВНЫЕ ВЗАИМОДЕЙСТВИЯ В СОЛНЕЧНОЙ СИСТЕМЕ
Authors: Гудкова Т.В.
Published: June 2024

Наша Солнечная система представляет собой семейство планет и спутников, сформированных из горных пород, льда, газа, а также их смеси. Для изучения недр Земли был разработан большой арсенал геофизических методов, но возможности для исследования строения других тел Солнечной системы остаются ограниченными. Широкий набор сейсмических данных доступен только для Земли, хотя сейсмические эксперименты были проведены на Луне и Марсе. Такие эксперименты очень дорогостоящие, и поэтому многие исследования планет опираются на дистанционное зондирование и геодезические измерения.
МАРС ПОДАЕТ ПРИЗНАКИ ЖИЗНИ
Authors: Говорова А.Ф.
Published: June 2024

Молодой Марс был очень похож на раннюю Землю. С большой долей вероятности планетологи говорят о том, что в определенный промежуток времени до 3.6 млрд лет назад климат на Марсе был теплым и влажным, атмосфера достаточно плотной и мощной, на поверхности текли реки, формировались озера, а какое-то время существовал даже океан. Именно тогда там могла появиться жизнь. Во всяком случае, если мы правильно понимаем палеоисторию Марса и условия, необходимые для возникновения жизни, ничего этому не препятствовало.
Ecological Studies and Epidemiological Aspects of Leptospirosis in the Northeast Region of Brazil
Authors: Amorim Brenda Vitória Machado , Cova Gabriella Mascarenhas , Silva Carlos Danilo Cardoso Matos , Neto João Ronaldo Tavares de Vasconcellos
Published: June 2024

Introduction: Leptospirosis, a globally prevalent zoonotic infection, affects approximately one million people annually. Originating from the bacterium Leptospira, it is transmitted through contact with the urine of reservoir animals, such as rodents. In Brazil, it is endemic, especially in the Northeast region, where poor sanitary conditions contribute to its dissemination. The objective of this study is to analyze the main determining factors for the increase in leptospirosis cases in the Northeast region of Brazil, with an emphasis on rainfall patterns and deficiencies in basic sanitation.
Methodology: The methodology consisted of a qualitative exploratory-descriptive bibliographic review of articles published between 2014 and 2024 in Portuguese, English, and Spanish. Inclusion criteria were relevance to the topic, while exclusion criteria involved duplicated articles or those that did not highlight the content of interest. The search was conducted in databases such as LILACS, SciELO, and PubMed, using specific descriptors. The analysis involved careful selection and exhaustive reading for the categorization of results.
Results and Discussion: Leptospirosis impacts urban and poor areas, with over one million annual cases globally. Factors such as precipitation and disordered urbanization contribute to its spread, especially in tropical regions. Low-income populations are vulnerable due to the lack of basic sanitation. The unequal distribution reflects socio-economic disparities, with densely populated urban areas being more affected.
Conclusion: Leptospirosis poses a challenge to public health, especially in regions with poor sanitary conditions. Effective control requires a comprehensive approach, including improvements in sanitation infrastructure, health education, and rodent control.
Exploring DNA Analysis Methods and Genetic Research Applications in Low and Middle-Income Nations: A Study of Sri Lanka
Authors: Jaythissa Prabath , Rupasinghe Avanthi
Published: June 2024

Using Sri Lanka as a case study, the paper explores how DNA analysis has transformed genetic research, particularly in low and middle-income countries (LMICs). It discusses various DNA analyzing techniques, from traditional methods like Sanger sequencing to advanced techniques such as next-generation sequencing (NGS) and CRISPR-Cas9, highlighting their applications in disease research, population genetics, and forensic science. Sri Lanka's advancements in genetic research, including DNA sequencing, typing, and recent developments in X-chromosome-based DNA typing, are emphasized. The paper also examines challenges and opportunities in LMICs regarding genetic research and underscores the importance of DNA analysis in advancing personalized medicine and understanding genetic diversity. Additionally, it discusses Sri Lanka's efforts in education and training in molecular biology. It explores the country's rich genetic diversity and demographic history, focusing on ethnic studies and historical interactions among different population groups. Overall, the paper highlights the significance of DNA analysis in genetic research and its potential implications for LMICs. Sri Lanka is a notable example of progress in the field.
Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) Revealing Polycythemia Vera: A Case Report
Authors: Haless Kamal , Ali Eljazouli , Arous Amina , Drighil Abdenasser , Habbal Rachida
Published: June 2024

Introduction: Acute myocardial infraction typically associated with atherosclerosis and coronary lesions, can occur without significant stenosis, implicating microcirculatory obstruction.
Case Presentation: We present a case of a 60-year-old woman with hypertension and atrial fibrillation who was admitted with chest pain. Initially diagnosis of high-risk NSTEMI, but coronary angiography showed no significant lesions. Cardiac MRI revealed myocardial necrosis, indicating myocardial infraction with non-obstructive coronary arteries (MINOCA). Further investigation identified polycythemia vera as the cause. The patient was transferred to the hematology department and discharged with DAPT, atorvastatin, and bisoprolol.
Conclusion: The case presented illustrates the importance of recognizing polycythemia vera as an important cause of thrombosis, not only of MI with significant coronary lesion, but also of MI with non-obstructive coronary arteries.
Extraction and Purification of Squalene from Virgin Olive Oil via Catalytic Transesterification and Molecular Distillation
Authors: Manikyam Hemanth Kumar , J Dhanaseelan , Mani Jayaraj
Published: June 2024

Squalene, a highly valuable compound abundant in various natural sources, shows great potential in pharmaceutical, cosmetic, and nutraceutical applications. This research article outlines a comprehensive methodology for extracting and purifying squalene from virgin olive oil, a rich source of the compound. The extraction process begins with degumming, which involves heating the olive oil to 60-70°C to reduce viscosity, followed by the addition of 2-3% warm water to hydrate phospholipids. Food-grade phosphoric acid is then added to react with the phospholipids, forming precipitates. The mixture is stirred for 20-30 minutes and allowed to rest for an additional 20-30 minutes, enabling impurities to settle. The upper layer of degummed oil is separated via decantation or centrifugation and washed with warm water for pH adjustment. Next, transesterification is performed by mixing 100 ml of virgin olive oil with 25% methanol (w/w) and a catalyst (0.5% sodium methoxide or PTSA), and heating the mixture to 80-90°C under reflux for 1-2 hours. Following transesterification, the solvent and acetone are distilled out, and acetone precipitation is repeated 2-3 times to remove unsaponified matter, which is then filtered and evaporated. The concentrated oil undergoes molecular distillation at 180°C and 0.0033 bar pressure for 1 hour, yielding the distillate and residue for further analysis. Qualitative analysis using Thin Layer Chromatography (TLC) involves Merck TLC plates with silica gel 60 F254 and a hexane: chloroform (9:1) mobile phase. Spots are developed with a 10% HCl solution, confirming the presence of squalene with an RF value of 0.93. Quantitative analysis via High-Performance Thin-Layer Chromatography (HPTLC) employs Merck TLC plates with cyclohexane as the mobile phase and CAMAG at 254 nm and 366 nm wavelengths, revealing a squalene purity of 67% and a recovery rate of 69.8%. The initial purification through transesterification facilitated the conversion of ester groups, yielding squalene-rich fractions, while acetone precipitation effectively removed saponified matter. Molecular distillation further enhanced squalene purity. TLC analysis confirmed the qualitative presence of squalene, and HPTLC provided precise quantitative measurements. The obtained squalene purity of 67% significantly enriches the initial content in virgin olive oil, though further optimization could enhance purity and yield. Complementary techniques like GC-MS or HPLC could validate the purification process. This study presents an efficient, replicable procedure for extracting and purifying squalene from virgin olive oil, with significant implications for pharmaceutical, cosmetic, and nutraceutical industries. The findings support a sustainable and ethical shift towards vegetable-derived squalene, meeting market demands while ensuring high-quality production.
Epidemiology of Gastrointestinal Helminths Infection in Buffalo of New Alluvial Zone of West Bengal, India
Authors: Jas Ruma , Kumar Dhananjay , Pandit Soumitra , Baidya Surajit , Nandi Abhijit
Published: June 2024

Aims: Epidemiology of naturally occurring gastrointestinal (GI) helminths was studied in buffalo of New Alluvial Zone of West Bengal and the role of different factors such as season, age, sex and rearing practices on prevalence was also recorded in the present study. 
Methodology: Monthly 120 faecal samples of buffaloes of New Alluvial Zone (NAZ) were collected and examined by standard parasitological techniques from April, 2016 to March, 2017.
Results: The overall prevalence of GI helminths was recorded as 46.53% in buffalo of NAZ in West Bengal. Paramphistome (35.9%) was observed as the predominant parasite followed by Strongyle (9.93%), Fasciola (4.17%) and Toxocara (4.03%). Monsoon (54.58%) was found to be the most favourable season followed by winter (44.79%) and summer (40.21%) for GI helminths infection in buffalo. The overall prevalence (52.57%) as well as prevalence of Strongyle and Toxocara was higher in young buffaloes than the adult buffaloes (44.47%). The overall prevalence of GI helminths was higher in female buffalo (48.85%) than the male (40.74%) and the prevalence of individual parasites did not vary greatly between the two sexes of animals. Semi-intensive system (54.46%) of rearing showed higher prevalence of GI helminths than the intensive method (39.07%). Prevalence of Strongyle, Fasciola and Paramphistome was comparatively higher in animals maintaining under semi-intensive system than the intensive system of rearing.
Conclusion: The results of the present study might be utilized for planning control programme against GI helminths in buffaloes of NAZ of West Bengal.
Effect of Crop Residue Management and Weed Management Practices on Nutrient Content and Nutrient Uptake in Wheat (Triticum aestivum L.).
Authors: Tripathi Ankur , Singh Anil Kumar , Kumar Rajesh , Kumar Neeraj , Kumar Abhinav , Tripathi Manoj Kumar , Gupta Satya Prakash
Published: June 2024

The field experiment was carried out during two successive Rabi seasons of 2021-22 and 2022-23 at the Agronomy Research Farm of Acharya Narendra Deva University of Agriculture & Technology, Kumarganj, Ayodhya (U.P.).The treatment combinations of 4 crop residue management, viz. conventional tillage without residue, conventional tillage with residue (3 t/ha rice residue), zero tillage without residue, zero tillage with residue (3 t/ha rice residue) and 5 weed management practices, viz. Triallate 50% EC @ 1250 g a.i. ha-1, Triallate 50% EC @ 2500 g a.i. ha-1, Clodinafop propargyl 15% + Metsulfuron methyl 1% (60 g + 4 g a.i. ha-1),  hand weeding at 20 and 40 days after sowing (DAS) and weedy check in wheat were tested with 3 replications in split-plot design, keeping crop residue management in main plots and weed management practices in subplots. Among the different crop residue management, zero tillage with residue was found most effective in maximizing nutrient content and nutrient uptake followed by conventional tillage with residue. Conventional tillage without residue showed lowest values of on nutrient content and uptake by crop. While in case of weed management practices hand weeding at 20 and 40 days after sowing (DAS) had a significant impact on maximizing nutrient content and nutrient uptake followed by post-emergence application of Clodinafop propargyl 15% + Metsulfuron methyl 1% (60 g + 4 g a.i. ha-1).
Optimizing Inoculation Techniques for Enhanced Rust Disease Pressure in Fig Trees: Insights on Cerotelium fici Multiplication and Maintenance
Authors: Lohate, S. R.  , Khaire, P. B  , Bansode, G. M.
Published: June 2024

Fig rust is one of the most prevalent diseases caused by Cerotelium fici is an obligate parasite and it has to be maintained only on its own host. The present study was taken into consideration to check the comparative effectiveness of various inoculation methods for inducing disease symptoms, maintaining and multiplying inoculums, and examining the slow rusting mechanism. For this, a polyhouse experiment using the Poona fig cultivar was conducted at the National Agricultural Research Project, Ganeshkhind, Pune. Ninety-days-old three fig layers, each with four to five healthy leaves, were inoculated in the evening using six different inoculation methods. The suspension of urediospores used for inoculation was made with 5 X 108 spores ml-1 in sterile water. The result of the study revealed that, leaf dip, micro droplet and hand inoculation methods were found most effective for mass multiplication and maintenance of C. fici.
Applying the Parameters of Impacted Population and Gully Social Impact Factor to Prioritize Choice of Gully Erosion Intervention Programs in Resource Limited Settings: Lessons from World Bank Funded Intervention in Anambra State, Nigeria
Authors: EC Obiano , EE Onuchukwu , GC Azuchukwuene , VN Ojeh , FC Mbaneme , DC Nwogbo , PC Okorie , JE Edochie
Published: June 2024

Background: Following a presidential request for assistance in the gully erosion menacing many States in Nigeria, the World Bank intervened through the Nigeria Erosion and Watershed Management Program (NEWMAP) in 23 States including Anambra, from 2014 - 2022. This study examined NEWMAP’s intervention in order to learn crucial lessons to improve subsequent gully remediation interventions in Anambra State.
Methods: A 7-man multidisciplinary focus group was constituted to study NEWMAP’s intervention in Anambra State, determine the most striking innovation in the intervention, and explore that innovation further. Data extraction, content analysis comparative analysis, rational decision framework and the deductive model were applied to make findings and draw conclusion.
Results: The study found that: (i) the most striking innovation in NEWMAP’s intervention in Anambra State is the introduction of elaborate and comprehensive package of rehabilitation of impacted population. (ii). 13 major gully erosion sites were remedied totaling 32 544.87 meters long and directly impacting a population of 163 209 persons (iii). As at June 2021, 150 000 impacted population had benefitted from micro-credit grants to engage in alternative livelihood businesses that contributed in revamping the State’s economy. (iv). The 13 gully sites remedied had a wide range of gully social impact factor, the highest three values being 101 440; 67 587.5 and 41 778; while the lowest three values are 1 204; 1 694.7 and 3 186.
Conclusion: The study concludes that elaborate and comprehensive package of rehabilitation of gully impacted population is an innovation in Anambra State introduced by NEWMAP; that gully impacted population is a good measure of vulnerability; and that the parameters of impacted population and gully social impact factor are sensitive, reliable and effective parameters to prioritize choice of gully intervention programs in resource-limited settings.
Economics of Various Treatments of Vermicompost on Growth and Yield Attributes of Pea (Pisum sativum L.) Based Intercropping System
Authors: Verma Astha , Aravindakshan Kavita , Sharma Rajesh Kumar , Chopra Rahul , Bhatnagar Prerak , Tippannavar Ajit
Published: June 2024

Intercropping is an ecologically friendly technique that can increase the sustainability of farming systems, whilst considered as low input systems. An experiment was conducted at the vegetable farm, Department of Vegetable Science, College of Horticulture and Forestry, Jhalrapatan City, Jhalawar during the rabi season from November, 2022 to April 2023. The experiment comprised fifteen treatment combinations having three levels each of vermicompost (0, 2.5, and 5 ton/ha) and five levels of different intercropping system (Sole Pea, Sole Garlic, Pea + Garlic 1:1, 2:1, 2:2) in Factorial Randomized Block Design with three replications. The result of the present investigation showed that the effect of vermicompost and intercropping system on individually and combined had significant effect on the economic related attributes. The interaction effect of the Vermicompost and Intercropping system significantly increased the economic attributes such as maximum gross return (361172 ₹ ha-1), net profit (272244 ₹ ha-1) and B:C ratio (4.06) was recorded under treatment V2I5 (Vermicompost @5ton/ha+ Pea+ Garlic 2:2) as compared to other treatment, respectively. The interaction effect of vermicompost and Intercropping system also significantly increased pea equivalent yield (166.040 q/ha), land equivalent ratio (1.25) under treatment V2I5 (Vermicompost@5ton/ha+ Pea+ Garlic 2:2), respectively.