bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of SR-BI gene rs4238001 and rs5888 polymorphisms prevalence and effects on Turkish patients with metabolic syndrome
Authors: Filizfidan Mehmet , Pence Sadrettin , Çaykara Burcu , Alsaadoni Hani , Marakoğlu Kamile , Pençe Halime Hanım , Kargın Nisa Çetin
Published: October 2019

Aim

Metabolic syndrome (MS) is associated with dyslipidemia such as hypertriglyceridemia and high-density lipoprotein (HDL) levels. Scavenger receptor BI (SR-BI) is the transmembrane receptor that regulates selective intake of cholesterol esters by the liver and it binds to HDL with high affinity. This study was aimed to determine the effects of SR-BI gen variations upon proatherogenic and antiatherogenic lipid profiles in the patients with metabolic syndrome.

Methods

The patient group was consisted of 104 (30–65 years) male subjects who were diagnosed with MS and 100 healthy male subjects were included in control group. DNA was isolated from blood samples. SR-BI gene rs4238001 and rs5888 variants were examined by SNaPshot multiplexing system. SPSS 18 was used for statistical analysis and p<0.05 considered as statistically significant.

Results

It was found that SR-BI gene rs4238001 T allele increased the risk of metabolic syndrome 1.61 fold (p=0.02). Subjects with TT genotype 2.847 fold increased the risk of metabolic syndrome according to subjects with CC genotype (p=0.017).

Conclusions

SR-BI rs4238001 variation may be related to an increased risk of metabolic syndrome.
Sustainable Finance
Authors: Bueren Eckart
Published: October 2019

Mit dem Aktionsplan „Finanzierung nachhaltigen Wachstums“ der Europäischen Kommission steht Sustainable Finance im Zentrum unionsrechtlicher Kapitalmarktregulierung und wird von einem Nischenangebot in den Mainstream rücken. Der vorliegende Beitrag widmet sich zunächst den Grundlagen, der Geschichte und Bedeutung von Sustainable Finance. Sodann analysiert er den Stand der Verrechtlichung von Sustainable Finance und untersucht darauf aufbauend die jüngsten Reformschritte auf Unionsebene.
A 2-Level Iterated Tabu Search Algorithm for the Quadratic Assignment Problem
Authors: Misevičius Alfonsas , Kuznecovaitė (Verenė) Dovilė
Published: October 2019

In this paper, a 2-level iterated tabu search (ITS) algorithm for the solution of the quadratic assignment problem (QAP) is considered. The novelty of the proposed ITS algorithm is that the solution mutation procedures are incorporated within the algorithm, which enable to diversify the search process and eliminate the search stagnation, thus increasing the algorithm’s efficiency. In the computational experiments, the algorithm is examined with various implemented variants of the mutation procedures using the QAP test (sample) instances from the library of the QAP instances – QAPLIB. The results of these experiments demonstrate how the different mutation procedures affect and possibly improve the overall performance of the ITS algorithm.
Semantic Segmentation of Eye Fundus Images Using Convolutional Neural Networks
Authors: Toliušis Ričardas , Kurasova Olga , Bernatavičienė Jolita
Published: October 2019

This article reviews the problems of eye bottom fundus analysis and semantic segmentation algorithms used to distinguish the eye vessels and the optical disk. Various diseases, such as glaucoma, hypertension, diabetic retinopathy, macular degeneration, etc., can be diagnosed through changes and anomalies of the vesssels and optical disk. Convolutional neural networks, especially the U-Net architecture, are well-suited for semantic segmentation. A number of U-Net modifications have been recently developed that deliver excellent performance results.
Development Potential of Public and Private Partnership of Southern Russian Regions for Implementing Infrastructural Projects
Authors: Ivanov Vladimir
Published: October 2019

The necessary condition determining the steady growth and security of economic development is full functioning and development of infrastructure.
The article emphasizes that the observed instability of real expenditures of the federal budget and territorial entities of the Russian Federation for infrastructural industries and also their uneven distribution both from the point of view of the economic sector and the region proved the need of searching non-budgetary sources for encouraging the economic development. Public and private partnership is thought to be a fundamental instrument of private investment attraction.
The article states the possibilities of participation of private firms in implementing infrastructural projects in combination with the government support when the integral powers and immanent functions of the state remain. The interests of using this instrument for the government lies in the budget expenditure reduction, increase in their efficiency, implementation of obligations of various character, in particular social ones. For private enterprises these interests are presented by governmental guarantees, the distribution of risks, possibility of participation in long-term projects and attraction of debt financing, political support of the state.
Despite the dominating role of the government participation in implementing infrastructural projects, the value of public and private partnership from the point of view of financial security increases every year.
The mutually agreed policy and coordination of joint efforts for expanding and mobilizing financial resources and implementing and modernizing infrastructural projects using these funds is expected to become a basis for the interaction of the government and private organizations.
The article analyzes the available potential of the regions of Southern Russia in the context of creating conditions for developing public and private partnership for implementing infrastructural projects. The information for this research is the systematized data of the PPP Development Center. The author presents the best examples of implementing infrastructural projects with the attraction of private investments. The paper points out the priority infrastructural projects implemented with the use of the public-private partnership mechanism, which is planned for implementing in the region as well. The assessment of the level of public and private partnership development in the regions under analysis confirmed the increasing potential of the investment attraction for implementing infrastructural projects.
On the basis of the analysis of the institutional environment development condition and legal basis, the author makes a conclusion on the decrease of the importance of these factors when determining the rating of regions of Southern Russia in the sphere of public and private partnership and an increase of such an indicator as “Experience of implementing projects”.
Increase of the Infrastructure Competitiveness of the Republic of Crimea on the Basis of Public and Private Partnership
Authors: Ostovskaya Anastasiya
Published: October 2019

The article maintains the idea that regional development and the growth of its competitive power in the conditions of a new economic system evolving in Russia requires the creation of an adaptive and regulated infrastructural system. The competitive power of a separate region is currently defined by a well-organized infrastructure system corresponding to the existing conditions.
Therefore, the article offers the author’ concept of the regional mechanism of competitiveness based on the infrastructural development that can be applied regionally. The tools for its implementation are also identified. The findings of the research suggest that public and private partnership performs as an efficient tool of regional infrastructural development, whereas infrastructure itself has a significant impact on the competitive power and innovative potential of the region. The author presents the stages of the infrastructural project development. The analysis of the legal acts regulating the public and private partnership in Russia and the Republic of Crimea shows that the mechanism of public and private partnership remains to be a comparatively new phenomenon for Russia, whereas in the Republic of Crimea the legal framework is still being developed.
The author proposes the mechanism of public and private partnership as a means of the implementation of major socially oriented projects by means of mutual efforts of governmental authorities and private businesses. The advantages of such public and private partnership projects are defined for both parties – the state and private investors.
Public and private partnership allows expanding into new market segments, developing various economic sectors and implementing innovations, providing the competitive power of the region, improving the corporate social responsibility of businesses and thus this type of cooperation contributes to the reduction of social tensions in the region and a better life quality.
E-Commerce Company Valuation: Regional Features
Authors: Anikina Irina , Marchukova Yulia
Published: October 2019

Russian e-commerce market shows positive trends with regard to its core aspects that define market size and performance. To consummate e-commerce market transactions in a proper manner, as well as to select a further growth strategy for a company, one needs to correctly determine the market value of e-commerce companies. The market value is affected by such factors as the company’s location and regional presence. The purpose of this paper is to research into the possibilities of taking due account of regional specific features when determining the market value of e-commerce companies.
The paper also analyzes Russian e-commerce market performance and trends in its evolution, as well as changes in customer dynamics in e-commerce, as illustrated by the Southern Federal District of the Russian Federation. The paper proposes a plan for how one should take due account of the specific features of regional e-commerce market, through the example of a company engaged in e-commerce business in Volgograd Region. The article also includes an overview of currently available approaches to company valuation in e-commerce, as well as the methods of existing risks assessment.
The following growth drivers have been identified for the Russian e-commerce market: “side effects” of networks, complementarity of various Internet trade components, and low operating costs. Consequently, the key aspects of company valuation in e-commerce, as identified and segmented region-wise, are further being translated into the key factors that have a direct impact on the total value of the companies under valuation. Such impact factors include the number of potential customers in the region, change trends with regard to retail turnover in the region, and e-commerce market share depending on the population size of the region.
Current Issues of the Formation of Regional Agroindustrial Clusters
Authors: Kushnarenko Tatiana , Fomina Irina
Published: October 2019

The article analyzes the features of regional economy in the South of Russia, which is characterized by the diversity of agricultural enterprises. The paper shows that enterprises of the agro-industrial complex tend to integration in order to ensure the continuity of agricultural processes. The article studies the factors of regional development as an objective precondition for the formation of highly efficient clusters in the agro-industrial complex. The author proves that implementing the continuous scenario of the economy development and import substitution process is caused by a number of reasons including a low reaction rate to changes in market conditions; difficulties in obtaining loans; high tariffs for the transportation of agricultural products; changes in taxation. The paper determines that uniting agricultural enterprises in the agro-industrial cluster provides system benefits and guarantees a synergistic effect in the following forms: transforming the sectoral structure in the agro-industrial complex; creating the conditions for simultaneous improvement of performance indicators in cluster enterprises and administrative-territorial entities, within which enterprises are located; the organization of the agro-industrial cluster as a closed contour and, through this, reducing total costs and optimizing taxation of cluster enterprises; creating the mechanism of effective interaction with territorial authorities in implementing the regional import substitution policy; expanding access to new technologies and staff training in order to respond faster to changing market conditions in accordance with the requirements of the modern economy.
Building a Network that Will Pray for You
Authors: Cole Moshe
Published: October 2019

For many the term networking is cringe worthy. They picture awkward networking events, fake smiles, and sweaty handshakes. But is there another way? Can we network without feeling uncomfortable and like we are simply using people? Networking with the intent to build social capital is a viable alternative to traditional networking and presents networkers with comfort and peace of mind.

In this paper we explore what social capital is and how it differs from networking. We discuss the importance of social capital and its components. Finally, we explore how one can build social capital through networking and introduce practical steps that can assist any individual to improve their networking. Ultimately, this paper will help individuals & organizations network more comfortably, efficiently and successfully.
World Policy Analysis
Authors: Djita Rian , Hill Ashley
Published: October 2019

Food is one of the fundamental aspects of human existence. Thus, it important for every country in the world to be able to be food-secure. Providing access to food for its citizens will bring positive long-term impacts ranging from economic growth and job creation, poverty reduction, trade opportunities, increasing global security and stability, and also improving health and healthcare in a nation (National Institute of Food and Agriculture, n.d.). However, not every nation has the capacity to achieve that goal due to several contributing factors such as 1) Drought and other extreme weather events, 2) Pests, livestock diseases and other agricultural problems, 3) Climate change, 4) Military conflicts, 5) Lack of emergency plans, 6) Corruption and political instability, 7) Cash crops dependence, 8) AIDS as it reduces the available workforce in agriculture and puts an additional burden on poor households, 9) Rapid population growth. 

Yemen, and Burundi were intentionally chosen to be analyzed because of their unambiguous differences in order to show the various needs and solutions of each country. These 2 countries represent different rankings in the Global Food Security Index (GFSI 2018) where Burundi became the lowest ranking country, yet poses an interesting connection to Yemen. Yemen was selected because of the current famine crisis happening. From the analysis conducted, it can be concluded that long-standing conflict, Scarcity of basic needs, blockade of import and export activities are the main factors contributing to Yemen's food insecurity. On the other hand, it was found that Gender inequality especially the role of women in labor force, climate shock, and political instability are the main factors contributing to Burundi's food insecurity.
Stranger Under Siege
Authors: Maples Gordon Wilson
Published: October 2019

This case study and analysis explores the brief, 17-month tenure of Sam Olens as President of Kennesaw State University, including his controversial appointment, leadership mis-steps, and eventual resignation. The political and social contexts of his tenure, which coincided with political turmoil in the wake of the 2016 election and a subsequent resurgence in progressive activism throughout the country, are considered as contributing factors to his downfall. Likewise, his status as an outsider to higher education at the time of his appointment, his visibility as an outspoken conservative, and his employment being the perceived benefit of political corruption are all noted as a contributing elements to his inability to earn the confidence of the faculty and student body of Kennesaw State University, along with his divisive, misguided, and ill-conceived actions while in his executive position. The role of institutional context in regards to the recent histories of Kennesaw State University, the University System of Georgia, and the state of shared governance in American higher education as a whole are respectively explored in how they set the stage for Olens’ tumultuous and temporary reign at Kennesaw State. A set of recommended courses of action are presented as counterfactual alternatives to the events as they actually occurred, based on higher education leadership literature.
About the Iris Journal of Scholarship
Authors: Cypert Catherine Elizabeth , Johnson Kelly , Santelli Fransisco , Woods Colby
Published: October 2019

The following is a brief history of the Iris Journal of Scholarship and includes biographies of its founding leaders.
Taking into account nonquadratic detection of measurement result processing of waveguide device parameters
Authors: Afonin I , Berdyshev S , Ovcharov P , Salamatin V
Published: October 2019

The method of current-voltage characteristic determination of a detector in a microwave interference measuring device is proposed. The algorithm for result processing measurement of waveguide device parameters is provided. The algorithm takes into account a calculated exponential quantity.
The autodyne radio spectroscope: the brilliant invention of Ye. K. Zavoisky
Authors: Noskov V
Published: October 2019

The present paper concerns the preconditions served as the basis for the scientific discovery of the phenomenon of paramagnetic resonance, the stages of its development are discussed. The first stage is associated with the invention of the principle of autodyne reception of radiotelegraph signals with the help of the Meissner oscillator in the beats mode (Henry Round, 1913). The next stage is the autodynes usage as transceivers of radio altimeters designed to determine the height of an aircraft above the Earth's surface (Ernst Alexanderson, 20-30s). At the 3rd stage, the autodyne sensors of proximity for remote fuses have been proposed for aircraft bombs and rocket projectiles (William Alan Stewart Butement, 1939) and sensors for anti-aircraft shells that can withstand mechanical overload during an artillery shot (Merle Antony Tuve). At that, the new compounds were used to fill the nodes of electronic circuits and for the first time - the technology of PCB. In physical experiments, the autodyne becomes a tool by which the discovery of the phenomenon of the electron paramagnetic resonance (EPR) was made. The associate professor of the Department of physics of Kazan State University Ye. K. Zavoisky became the author of this discovery, and the founder of a new direction in physics. Description of the operation principle is given and the acting device of the autodyne radiospectroscopy he created, which working model is illustrated in the museum-laboratory of Ye. K. Zavoisky in Kazan State University. The contribution of the development of the VHF range (together with P. M. Vinnik), as well as in the theory and technique of autodyne and super-regenerative reception of radio signals.
Los materiales usados en escuelas de Educación Infantil proyectados en sus webs y blogs
Authors: Rodríguez María Montserrat Castro
Published: October 2019

RESUMEN En España, la Educación Infantil (EI) no es una etapa de escolarización obligatoria, pero, en la actualidad casi el 100% del alumnado de 3-6 años está escolarizado. En los últimos años en la comunidad científica se ha despertado un interés por investigar sobre diferentes aspectos curriculares relacionados con la praxis educativa de esta etapa. En este marco, los materiales juegan un rol fundamental como mediadores para el acceso al conocimiento y también para el desarrollo de proyectos educativos. En paralelo, las políticas de incentivación del uso de las TIC en la sociedad y en la escuela generan nuevas formas traspasar muros: sus webs y blogs sirven de escaparate para que los centros dejen constancia de su trabajo. Este artículo presenta los resultados de una investigación que tiene dos objetivos: Identificar el tipo de materiales proyectados en los blogs y website de los centros educativos, y comprobar si éstos están contextualizados en la comunidad educativa.En esta investigación se seleccionan cuatro colegios que responde a cuatro modelos representativos en cuanto al uso de materiales y de webs/blogs. Es una selección intencionada a partir de los siguientes criterios: tipo de escuela, contexto socieconómico, uso de sus webs/blogs y tipos de materiales. Es una muestra de 27 aulas agrupadas en cuatro centros. El instrumento de investigación se elaboró a partir de los indicadores propuestos por Booth and Ainscow (2011). Los resultados indican que existe una cultura de compartir materiales; uso mayoritario de materiales de fuera de la comunidad excepto en los centros rurales. El uso de los blogs y website difiere: unos centros reflejan procesos y otros presentan los productos.
Monteiro Lobato e suas fases
Authors: Zilberman Regina
Published: October 2019

Resumo Exame do conjunto da obra de Monteiro Lobato, considerando sua trajetória e modificações suscitadas pela condições de produção e recepção.
Literatura infantil contemporânea: o passado (revestido) bate à porta
Authors: Ramos Flávia Brocchetto , Panozzo Neiva Senaide Petry
Published: October 2019

Resumo A literatura infantil contemporânea tem revelado uma tendência de atualizar discursos do passado por meio da criação de enredos que revelam conflitos localizados num tempo distante do leitor contemporâneo. Além dessa característica da literatura ela tem sido enriquecida pelo investimento na visualidade, de modo que os livros se constituem como objetos híbridos, e a leitura destas obras deve considerar, pois, aspectos postos tanto pela linguagem verbal como pela visual.
Literatura infantil brasileira e estudos literários
Authors: Lajolo Marisa
Published: October 2019

Resumo O artigo discute algumas feições assumidas pela produção e circulação de obras brasileiras contemporâneas voltadas para crianças e jovens a partir das transformações sofridas pela sociedade brasileira nos últimos 40 anos, sobretudo no que diz respeito ao financiamento e legitimação de bens culturais.
Acceptable Planning: Influencing Individual Behavior to Reduce Transportation Energy Expenditure of a City
Authors: Mohan Shiwali , Rakha Hesham , Klenk Matt
Published: October 2019

Our research aims at developing intelligent systems to reduce the transportation-related energy expenditure of a large city by influencing individual behavior. We introduce Copter - an intelligent travel assistant that evaluates multi-modal travel alternatives to find a plan that is acceptable to a person given their context and preferences. We propose a formulation for acceptable planning that brings together ideas from AI, machine learning, and economics. This formulation has been incorporated in Copter that produces acceptable plans in real-time. We adopt a novel empirical evaluation framework that combines human decision data with a high fidelity multi-modal transportation simulation to demonstrate a 4% energy reduction and 20% delay reduction in a realistic deployment scenario in Los Angeles, California, USA.

 

This article is part of the special track on AI and Society.
Thomas Hardy's Groundwork
Authors: Wright Daniel
Published: October 2019

Thomas Hardy strategically exposes what he calls the “groundwork” of his fictional worlds in scenes depicting blizzards or total darkness that scrub away all points of orientation. When Hardy reveals the empty field—”forms without features”—within which the details of the novel take shape, he aims to investigate the ontological, rather than epistemological or aesthetic, questions raised by novelistic realism. By tracing Hardy's groundwork through several novels, primarilyFar from the Madding Crowd(1874), TheReturn of the Native(1878), andTess of the d’Urbervilles(1891), the essay shows that Hardy's vexed relation to the realist tradition arises out of the metaphysical paradoxes endemic to novelistic mimesis.
The Innocent Old Way: Reserved Interpretation and Christina Rossetti's “Goblin Market”
Authors: Plourde Aubrey
Published: October 2019

Christina Rossetti's “Goblin Market” has long been recognized as an interpretive enigma. Simultaneously conducting its own surface reading and inviting us to interrogate its buried meanings, the poem adapts the Tractarian doctrine of reserve to set up a hermeneutic paradox rooted in Victorian exegetical thought. Variously a standard for reticent poetic style, an apologia for divine mystery, and a prescription for limiting complex theological knowledge, reserve also served Victorian thinkers as a hermeneutic strategy. Rossetti plays reserve against itself by dramatizing its dueling imperatives—inciting and containing curiosity. Laura's epilogue forecloses interpretation for “illiterate” spiritual children—those who might misconstrue mysterious meanings; simultaneously, the epilogue mobilizes a competing dimension of reserve, juxtaposing its interpretive gatekeeping against its hermeneutic potential. Anticipating recent reading debates, Rossetti's reserve generates a temporally recursive hermeneutic, within which competing interpretations and interpretive modes can be imagined to coexist.
The Facts on the Ground
Authors: Brooks Peter
Published: October 2019

The facts on the ground: That is where investigation starts, and that is what the court will have to deal with during the trial. And beyond: if the case goes up to an appellate court, those facts will be retold in an effort to judge whether the law has been correctly applied to them—whether the facts were appropriately formalized, one might say. So the statement of facts is a genre within a genre, one that doesn't much interest legal scholars since it is supposed to be neutral, factual indeed—it's there so the more interesting legal work can go forward. But surely this genre within a genre is interesting in itself.
Facts, Faction, Anachronism
Authors: Castronovo Russ
Published: October 2019

Temporal concerns are baked into the matter of facts. From an etymological point of view, facts are moments of making and doing that are no longer alive and kicking. Coming into English and other modern Western languages by means of both the past participle of the Latin wordfacere(“to make or to do”) and the Latin nounfactum, whose senses include the “result of doing” and “something done,”factdenotes an action that has happened and is now preserved like a fossil in the accumulated sediments of history (“Fact”). Etymologically speaking, facts are safely removed from the vicissitudes of the present and the whims of our leaders. So it makes sense that there should be some hand-wringing over facts that have become so thoroughly destabilized that they no longer seem to be based on anything. The defining moment in this distressing development occurred when the Trump administration, not content merely to put a spin on facts, dismissed quantifiable facts by summoning “alternative facts” to deny that the low attendance at the 2017 presidential inauguration was real. A dictionary, not the renowned one from Oxford butUrban Dictionary, offers the following definition ofalternative facts:“an attempt to gaslight the population in an effort to control the media and create propaganda” (Mozzy-o). If only we could take refuge in etymology and remind ourselves and anyone else who will listen that facts are veritable faits accomplis, over and done with, past participles that stand as linguistic monuments to a bygone event beyond alteration.
Eğitsel Oyunların Öğrencilerin Yabancı Dil Olarak Türkçe Öğrenmeye Dönük Tutumlarına ve Konuşma Becerilerine Etkisi
Authors: KORKMAZ Özgen , İNAL Murat
Published: October 2019

Bu araştırmanın amacı
eğitsel oyunların öğrencilerin yabancı dil olarak Türkçe öğrenmeye dönük
tutumlarına ve konuşma becerilerine etkisini belirlemektir. Bu çalışma yarı
deneysel araştırma deseninin kullanıldığı nicel bir araştırmadır. Araştırmanın
çalışma grubunu Bursa İl merkezde bulunan bir ilköğretim okulunda eğitimlerine
devam eden geneli Suriye uyruklu olmakla beraber Azerbaycan, Özbekistan,
Sırbistan ve Rusya uyruklu toplamda 50 öğrenciden oluşmaktadır. Araştırma
kapsamında veriler Konuşma Değerlendirme Rubriği ve Tutum Ölçekleri (Cronbach
Alfa güvenirlik katsayısı=0,78) kullanılarak toplanmıştır. Araştırma süreci
boyunca deney grubu öğrencilerine eğitsel oyunlar seçilerek uygulanmıştır. Bu
uygulama toplamda 5 hafta sürecek şekilde planlamıştır. Kontrol grubunda ise
Türkçe dil bilgisi kurallarına uygun cümlelerle diyalog kurabilecekleri ortam
hazırlanmıştır. Veriler aritmetik ortalama, standart sapma ve t analizleri
kullanılarak analiz edilmiş ve şu sonuçlara erişilmiştir: Akıllı tahtaya dayalı
eğitsel oyunlar, öğrencilerin yabancı dil olarak Türkçe konuşma becerilerini
geleneksel yönteme göre daha fazla katkı sağlamakta ancak tutumlarında
değişiklikler meydana getirmemektedir.
Çeviri Çocuk Edebiyatı Eserlerinde Yer Alan Değerler Üzerine Bir Araştırma
Authors: BAŞ Bayram , BİROS Yeliz
Published: October 2019

Çocukların
hemen hemen tüm gelişim evrelerinde sözlü ve yazılı edebiyat ürünlerinden
faydalanılmaktadır. Çocuklar, okul öncesi döneminde dinleme becerileriyle, okul
döneminde ise hem dinleme hem de okuma becerileriyle çocuk edebiyatı eserlerine
ulaşmaktadırlar. Çocuk edebiyatı okuma alışkanlığı kazandırma sürecinde, ana
dili öğretiminde ve edebiyat okuru yetiştirmede olduğu kadar, değer aktarımında
da oldukça önemli bir yer teşkil etmektedir. 
Bu sebeple çocuk edebiyatı ürünlerindeki değerlerin farkında olunması ve
bu değerlerin niteliğinin incelenmesi gerekmektedir. Değerlerin içerisinde
evrensel değerler ve ulusal değerler yer almaktadır. Her ülkenin kendine has
ulusal değerleri vardır ve bunları korumak adına milli eğitimlerinin genel
amaçlarını ulusal değerlerine göre şekillendirmektedirler. Çocuk edebiyatı
ürünlerine dinleme veya okuma becerisiyle ulaşan çocuğun hedeflenen değerleri
kazanması daha da kesinleşir, kendisini öğrenerek eğitir ve yaşam boyu sahip
olacağı değerlerini belirlemesine katkı sağlar. Bu çalışmada, 6-10 yaş
aralığındaki çocuklara yönelik hazırlanmış çeviri romanların değerler eğitimine
katkıları tespit edilmiştir. Araştırmanın inceleme nesnelerini, 6-10 yaş
aralığındaki çocuklara yönelik 17 ülkeye ait birer öykü oluşturmaktadır. Öyküleri
tespit etmek amacıyla “Eğitim Sen İlköğretim Çocuk Edebiyatı Kitap Kataloğu”
içerisinde yer alan çeviri çocuk edebiyatı ürünlerinden olan öyküler, ait
oldukları ülkelere göre listelenmiştir. Bu listeden yararlanılarak bir form
oluşturulup, uzman görüşleri alınmıştır. Verilerin toplanmasında Schwartz
Değerler Listesi kullanılmıştır. Derecelendirme yüzde dağılımı şeklinde
yapılmıştır. Verilerin analizinde içerik analizi tekniklerinden kategorisel
içerik analizi kullanılmıştır. İncelenen eserlerde 869 değer tespit edilmiştir.
Bu değerlerin 108 tanesi güç, 55 tanesi başarı, 66 tanesi hazcılık, 55 tanesi
uyarılma, 211 tanesi özdenetim, 45 tanesi evrenselcilik, 102 tanesi
yardımseverlik, 50 tanesi geleneksellik, 83 tanesi uyum, 94 tanesi de güvenlik
değerlerini oluşturmaktadır.
Policy implementation considerations for basic services: A South African urban sanitation case
Authors: Taing L
Published: October 2019

The Republic of South Africa formulated numerous progressive laws, regulations and strategies from 1994 to 2008 to support the provision of free basic sanitation access to the poor by 2014. The State has yet to achieve this objective in urban areas – ostensibly due to the poor municipal execution of national policy. This paper challenges this viewpoint, as it ignores policy weaknesses and overlooks the influence of non-municipal actors in service delivery. An assessment of national policy and implementation in South Africa’s second largest city (Cape Town) indicated that irreconcilable differences between municipal officials, residents and advocates’ interpretations of broadly-framed national policy, as well as policy gaps specific to servicing informal settlements and providing shared sanitation, contributed to the municipality’s failure to achieve policy objectives. The actors’ differences and policy shortcomings necessitated municipal policy reformulation according to the ‘lived’ and ‘practical’ realities of servicing informal settlements. The findings suggest a disproportionate focus on turning national policy into practice – for this viewpoint misses how local actors’ perspectives and current practices can shape policy. Understanding, accepting and addressing the interplay between policymaking and implementation can contribute to more constructive means of effectively delivering sanitation in South Africa.
Finding optimal algal/bacterial inoculation ratio to improve algal biomass growth with wastewater as nutrient source
Authors: Pham Le Anh , Laurent Julien , Bois Paul , Wanko Adrien
Published: October 2019

Algal growth, nutrient removal and settling efficiency were quantified while inoculating sequencing batch reactors with a mixture of microalgae and bacteria (activated sludge). Three algae/bacteria inoculation ratios (5:1, 1:1 and 1:5) as well as pure algal biomass (control) were assessed. Algal biomass production increased with the addition of activated sludge. However, the addition of too much activated sludge can cause disturbance to the Al-Bac biomass growth and algal bacterial processes. All reactors including the control with only algae showed similar settling and nutrient removal efficiencies. Good settling was observed in all reactors with only 5% of total biomass found in supernatant after 1 h of settling. Removal efficiencies of COD, TN and PO4-P in all reactors were 79–82%, 61–65% and 15–37%, respectively, with the lowest phosphorus removal efficiency belonging to 1:5 algae/activated sludge ratio. These results may be due to both long hydraulic (7 days) and solids retention times (up to 30 days). Finally, Al-Bac biomass with 1:1 inoculation ratio showed the best enhancement in terms of biomass growth and algal activities.
Modelling maize grain yield and nitrate leaching from sludge-amended soils across agro-ecological zones: A case study from South Africa
Authors: Ogbazghi ZM , Tesfamariam EH , Annandale JG
Published: October 2019

When applying municipal sludge according to crop N requirements, the primary aim should be optimizing sludge application rates in order to maximize crop yield and minimize environmental impacts through nitrate leaching. Nitrate leaching and subsequent groundwater contamination is potentially one of the most important factors limiting the long-term viability of sludge application to agricultural soils. This study assessed maize grain yield and potential nitrate leaching from sludge-amended soils, using the SWB-Sci model, based on crop nitrogen requirements and inorganic fertilizer. The following hypotheses were tested using the SWB­-Sci model and 20 years of measured weather data for 4 of the 6 South African agro-ecological zones. Under dryland maize cropping, grain yield and nitrate leaching from sludge-amended soils compared to inorganic fertilizer: (1) will remain the same across agro-ecological zones and sites, (2) will not vary across seasons at a specific site, and (3) will not vary across soil textures. Model simulations showed that annual maize grain yield and nitrate leaching varied significantly (P > 0.05) across the four agro-ecological zones, both for sludge-amended and inorganic fertilizer amended soils. The annual maize grain yield and nitrate leaching from sludge-amended soils were 12.6 t∙ha-1 and 32.7 kgNO3-N∙ha−1 compared to 10.2 t∙ha-1 and 43.2 kgNO3-N∙ha−1 for inorganic fertilizer in the super-humid zone. Similarly, maize grain yield and nitrate leaching varied significantly across seasons and soil textures for both sludge and inorganic fertilizer amended soils. However, nitrate losses were lower from sludge-amended soils (2.3–8.2%) compared to inorganic fertilizer (11.1–26.7%) across all zones in South Africa. Therefore, sludge applied according to crop N requirements has a lower environmental impact from nitrate leaching than commercial inorganic fertilizer. Further validation of these findings is recommended, using field studies, and monitoring potential P accumulation for soils that received sludge according to crop N requirements.
The effects of mutational profiles on phenotypic presentation of myeloproliferative neoplasm subtypes in Bosnia: 18 year follow-up
Authors: Kurtovic-Kozaric Amina , Islamagic Erna , Komic Hana , Bilalovic Nurija , Eminovic Izet , Burekovic Adnan , Uzunovic Amna , Kurtovic Sabira
Published: October 2019

The identification of mutually exclusive somatic mutations shared among myeloproliferative neoplasm (MPN) subtypes has provided a powerful tool for studying disease evolution. Clinical features, gene mutations, and survival over 18 years were analyzed in MPN patients. One hundred thirty-eight MPN patients were subcategorized according to MPN subtypes: essential thrombocythemia (ET, n = 41), polycythemia vera (PV, n = 56), primary myelofibrosis (PMF, n = 10), and MPN unclassified (MPN-U, n = 31). Patient characteristics included clinical parameters, overall survival, and mutational status of the JAK2, CALR, and MPL genes. We compared hematologic and clinical features of JAK2V617F-ET vs. CALR-mutated ET vs. JAK2V617F-PV patients. JAK2V617F-patients had higher values of erythrocytes, hemoglobin, and hematocrit compared to CALR-mutated patients (p < 0.05). The mutant allele burden in JAK2V617F-PV and JAK2V617F-ET patients directly correlated with erythrocyte, hemoglobin, and hematocrit values, but it inversely correlated with platelet count. Thus, mutant allele burden was an indicator of the clinical phenotype in JAK2V617F-MPN patients. OS was not affected by the mutational status. In general, mutated JAK2, CALR, and MPL genes left specific hematological signatures.
Orman Ürünleri Sanayi Sektöründe İş Kazası ve Ölümlü İş Kazalarının Türkiye ve Avrupa Birliği Ülkeleri Düzeyinde İncelenmesi
Authors: AKYÜZ Kadri Cemil , YILDIRIM İbrahim , AKYÜZ İlker , ERSEN Nadir
Published: October 2019

Üretim teknolojilerinde meydana gelen
değişim, daha düşük maliyetle daha fazla üretim yapma isteği ve firmaların
farklılaşan pazar koşullarında ayakta kalma zorunluluğu çalışma ortamlarında iş
sağlığı ve güvenliği açısından sorunları beraberinde getirmektedir. Gelişmiş ve
gelişmekte olan ekonomiler iş kazaları ve iş kazalarına bağlı oluşan ölümlerin
azaltılması için farklı yasal düzenlemeler yapmakta ve çalışan güvenliğini ön
plana çıkarmaya çalışmaktadır. Ülkemizde bu alanda yapılan yasal düzenlemelerin
önemli bir kısmı Avrupa Birliğine (AB) adaylık sürecinde oluşturulan uyum
yasaları çerçevesinde çıkarılmıştır. Yapılan yasal düzenlemelerin sektörel
boyutta nasıl sonuçlar verdiğinin belirlenmesinin amaçlandığı bu çalışmada
orman ürünleri sanayi sektörünü oluşturan üç alt sektörel yapının Türkiye ve AB
üyeleri ülkeleri düzeyinde karşılaştırılması hedeflenmiştir. 2008-2017 yılları kapsamında
ülkemiz ve AB üyesi ülkelerde meydana gelen iş kazası ve ölüm rakamlarının
istatistiksel açıdan incelendiği çalışmada özellikle 2013 yılında yürürlüğe
giren 5331 sayılı yasanın etkileri sorgulanmıştır. Çalışma sonucunda AB
genelinde tüm sektörel boyutlarda iş kazası ve ölüm rakamlarında oluşan azalma
karşısında ülkemizde incelenen yıllar düzeyinde sürekli artışların yaşandığı
belirlenmiştir. Çıkarılan ve uygulamaya çalışılan yasal düzenlemelerin yeterli
olmadığı ve güvenlik kültürünün oluşumuna yönelik çalışmaların
yoğunlaştırılmasının zorunlu olduğu tespit edilmiştir.
Propiedades psicométricas de un cuestionario para evaluar la percepción de los trabajadores de las políticas de recursos humanos y su compromiso organizacional
Authors: Ávila Vila Santiago , Pascual Faura Marcelo
Published: October 2019

El objetivo de este trabajo es desarrollar una herramienta que permita la evaluación del nivel de Compromiso Organizacional de los trabajadores y de la Percepción que estos tienen de determinadas Políticas de Recursos Humanos que inciden en este tipo de compromiso, para lo que se ha diseñado y contrastado las propiedades psicométricas de un cuestionario, que permitirá implementar estrategias de Dirección de Personas dirigidas a aumentar el nivel de compromiso de los trabajadores. Cuestionario que constituido por una parte ad hoc (ítems sobre las percepciones de sus políticas), y otra adaptada (organizational commitment questionnaire -OCQ- de Porter), fue cumplimentado por 706 sujetos (580 hombres y 126 mujeres). Los análisis factoriales exploratorios y confirmatorios realizados muestran que el modelo que mejor se ajusta a los datos obtenidos es el compuesto por cinco factores: compromiso organizacional, estilo de dirección, comunicación corporativa y reconocimiento, capacitación profesional, y retribución. La consistencia interna, estimada mediante el coeficiente α de Cronbach, es adecuada tanto para el cuestionario total como para cada uno de los factores.
Bangladesh National Serosurvey Vibriocidal Protocol (96-well plate, OD600, mAb) v1
Authors: Bhuiyan Taufiqur , Harris Jason , Jensen Owen , Leung Daniel , S Azman Andrew , Qadri Firdausi
Published: October 2019

This protocol provides the details on how vibriocidal assays were perfomed on serum from the nationally representative serosurvey for V. cholerae O1.
TotalSeq™-B or -C with 10x Feature Barcoding Technology v1
Authors: Li Sam
Published: October 2019

Buyer is solely responsible for determining whether Buyer has all intellectual property rights that are necessary for Buyer's intended uses of the BioLegend TotalSeq™ products. For example, for any technology platform Buyer uses with TotalSeq™, it is Buyer's sole responsibility to determine whether it has all necessary third party intellectual property rights to use that platform and TotalSeq™ with that platform. The following protocol describes surface protein staining with TotalSeq™–B and TotalSeq™–C antibodies and/or hashtag antibodies, to enable protein detection in addition to Single Cell 3’ v3 and Single Cell V(D)J Feature Barcoding technology from 10x Genomics. Please read the entire protocol before starting the experiments.
METABOLIC PATHWAY ANALYSIS BY LIQUID CHROMATOGRAPHY (UHPLC) COUPLED TO HIGH RESOLUTION MASS SPECTROMETRY (LC/MS) v2
Authors: S. Gouveia Angelica , L. Lima Lucas , S. Coutinho Flaviane , M. Rodrigues Juliano , J. M. Pinheiro Valquiria , Eduarda S. Ramos Maria , E. Vital Camilo , S.L. Pontes Claudia , P. Pinheiro Daniella , M. Vidigal Pedro , Barros Edvaldo , J O Ramos Humberto
Published: October 2019

Plants produce a variety of compounds with diverse structure and abundance that play an important role in the development, growth and response to the environment. Metabolomics involves studies of a great number of metabolites, which are small molecules present in biological systems.Metabolite profiles can be obtained from several samples by LC/MS (liquid chromatography coupled to mass spectrometry). However, the large number of ions detected for each run from different treatments and replicates require automatic processing for both spectra (metabolite identification and quantification) and global analysis of the metabolome. Thus, this protocol describes in detail, step-by-step, the comparison of the metabolite profiles from LC/MS data for determination of dysregulated pathways, as well as for Exploratory Statistical and Functional Enrichment Analyzes. .
TotalSeq™-A Antibodies Protocol with 10x Single Cell 3' Reagent Kit v2 v1
Authors: Li Sam
Published: October 2019

Buyer is solely responsible for determining whether Buyer has all intellectual property rights that are necessary for Buyer's intended uses of the BioLegend TotalSeq™ products. For example, for any technology platform Buyer uses with TotalSeq™, it is Buyer's sole responsibility to determine whether it has all necessary third party intellectual property rights to use that platform and TotalSeq™ with that platform. The following protocol combines highly multiplexed protein marker detection with unbiased transcriptome profiling for thousands of single cells. Epitope detection is enabled by BioLegend's TotalSeq™ antibody-oligo conjugates. TotalSeq™ reagents are compatible with Cellular Indexing of Transcriptomes and Epitopes by sequencing (CITE-seq), RNA Expression And Protein sequencing assay (REAP-seq), and similar workflows. Please read the entire protocol before starting the experiments.
Immunohistochemistry Protocol for Frozen Sections v3
Authors: Knight Kelsey
Published: October 2019

The following is a general procedure guide for preparation and staining of acetone-fixed frozen tissues using a purified, unconjugated primary antibody, biotinylated secondary antibody and streptavidin-horseradish peroxidase (SAv-HRP) and DAB detection system. Because each antigen differs in terms of requirement for fixation, amplification step, etc., it is not possible to write an inclusive protocol that will work for all antigens. The user must determine optimal conditions for each antigen of interest. Many protocols for staining individual antigens, as well as useful tips and troubleshooting guides for immunohistochemistry, can be found at the IHC World web site (https://www.ihcworld.com/).
On the Study of Sorption in the Chiral Separation of the Enantiomers of Salbutamol and Salmeterol by Supercritical Fluid Chromatography
Authors: Mikushina Irina V. , Bazarnova Natalya G. , Parenago Olga O. , Gensh Konstantin V.
Published: October 2019

The studied conditions of supercritical fluid chiral chromatography of salbutamol and salbutamol sulfate allowed to assumethe possibility of ionic interactions in the process of separation of enantiomers. It is shown that the structure of the hydrocarbon radical of 1- (4-hydroxy-3- (hydroxymethyl) phenyl) -2-aminoethanol associated with the chiral fragment, and, consequently, the physicochemical characteristics of the substance molecule, such as the number of hydrogen donors and acceptors polar surface, significantly affect the ability to communicate with the sorbent selectors under conditions of supercritical fluid chromatography
First‐Order Mantle Subduction‐Zone Structure Effects on Ground Motion: The 2016 Mw 7.1 Iniskin and 2018 Mw 7.1 Anchorage Earthquakes
Authors: Mann Michael Everett , Abers Geoffrey A.
Published: October 2019

The 24 January 2016 Iniskin, Alaska earthquake, at Mw 7.1 and 111 km depth, is the largest intermediate‐depth earthquake felt in Alaska, with recorded accelerations reaching 0.2g near Anchorage. Ground motion from the Iniskin earthquake is underpredicted by at least an order of magnitude near Anchorage and the Kenai Peninsula, and is similarly overpredicted in the back‐arc north and west of Cook Inlet. This is in strong contrast to the 30 November 2018 earthquake near Anchorage that was also Mw 7.1 but only 48 km deep. The Anchorage earthquake signals show strong distance decay and are generally well predicted by ground‐motion prediction equations. Smaller intermediate‐depth earthquakes (depth>70  km and 3<M<6.4) with hypocenters near the Iniskin mainshock show similar patterns in ground shaking as the Iniskin earthquake, indicating that the shaking pattern is due to path effects and not the source. The patterns indicate a first‐order role for mantle attenuation in the spatial variability of strong motion. In addition, along‐slab paths appear to be amplified by waveguide effects due to the subduction of crust at >1  Hz; the Anchorage and Kenai regions are particularly susceptible to this amplification due to their fore‐arc position. Both of these effects are absent in the 2018 Anchorage shaking pattern, because that earthquake is shallower and waves largely propagate in the upper‐plate crust. Basin effects are also present locally, but these effects do not explain the first‐order amplitude variations. These analyses show that intermediate‐depth earthquakes can pose a significant shaking hazard, and the pattern of shaking is strongly controlled by mantle structure.