bluuebunny/crossref_metadata_2025 huggingface dataset:
Window contamination on Expose-R
Authors: Demets R. , Bertrand M. , Bolkhovitinov A. , Bryson K. , Colas C. , Cottin H. , Dettmann J. , Ehrenfreund P. , Elsaesser A. , Jaramillo E. , Lebert M. , van Papendrecht G. , Pereira C. , Rohr T. , Saiagh K. , Schuster M.
Published: November 2014

Expose is a multi-user instrument for astrobiological and astrochemical experiments in space. Installed at the outer surface of the International Space Station, it enables investigators to study the impact of the open space environment on biological and biochemical test samples. Two Expose missions have been completed so far, designated as Expose-E (Rabbow et al. 2012) and Expose-R (Rabbow et al. this issue). One of the space-unique environmental factors offered by Expose is full-spectrum, ultraviolet (UV)-rich electromagnetic radiation from the Sun. This paper describes and analyses how on Expose-R, access of the test samples to Solar radiation degraded during space exposure in an unpredicted way. Several windows in front of the Sun-exposed test samples acquired a brown shade, resulting in a reduced transparency in visible light, UV and vacuum UV (VUV). Post-flight investigations revealed the discolouration to be caused by a homogenous film of cross-linked organic polymers at the inside of the windows. The chemical signature varied per sample carrier. No such films were found on windows from sealed, pressurized compartments, or on windows that had been kept out of the Sun. This suggests that volatile compounds originating from the interior of the Expose facility were cross-linked and photo-fixed by Solar irradiation at the rear side of the windows. The origin of the volatiles was not fully identified; most probably there was a variety of sources involved including the biological test samples, adhesives, plastics and printed circuit boards. The outer surface of the windows (pointing into space) was chemically impacted as well, with a probable effect on the transparency in VUV. The reported analysis of the window contamination on Expose-R is expected to help the interpretation of the scientific results and offers possibilities to mitigate this problem on future missions – in particular Expose-R2, the direct successor of Expose-R.
A Derivation of the Polytomous Rasch Model Based on the Most Probable Distribution Method
Authors: Noventa Stefano , Stefanutti Luca , Vidotto Giulio
Published: November 2014

Boltzmann’s most probable distribution method is applied to derive the Polytomous Rasch model as the distribution accounting for the maximum number of possible outcomes in a test while introducing latent traits, item characteristics, and thresholds as constraints to the system. Affinities and similarities of the present result with other derivations of the model are discussed in light of the conceptual frameworks of statistical physics and of the principle of maximum entropy.
Effects of News Stereotypes on the Perception of Facial Threat
Authors: Arendt Florian , Steindl Nina , Vitouch Peter
Published: November 2014

The human face is central to social interactions and therefore of primary importance in social perception. Two recent discoveries have contributed to a more thorough understanding of the role of news stereotypes in the perception of facial threat: First, social-cognition research has revealed that automatically activated stereotypes influence the perception of facial threat. Individuals holding hostile stereotypes toward dark-skinned outgroup members perceive ambiguous dark-skinned faces as more hostile than similar light-skinned faces. Second, media-stereotyping research has found that the media can influence individuals’ automatically activated stereotypes. Combining these two findings, it was hypothesized that reading tabloid articles about crimes committed by dark-skinned offenders would increase the perceived facial threat of meeting dark-skinned strangers in a subsequent situation. This hypothesis was tested in a laboratory experiment. Participants read crime articles where cues indicating (dark) skin color were mentioned or not. The results showed that reading about dark-skinned criminals increases the perceived facial threat of dark-skinned strangers compared with light-skinned strangers.
Erratum: Natural occurrence of microbial sulphur oxidation by long-range electron transport in the seafloor
Authors: Malkin Sairah Y , Rao Alexandra M F , Seitaj Dorina , Vasquez-Cardenas Diana , Zetsche Eva-Maria , Hidalgo-Martinez Silvia , Boschker Henricus T S , Meysman Filip J R
Published: November 2014

Correction to: The ISME Journal (2014) 8, 1843–1854; doi:10.1038/ismej.2014.41; published online 27 March 2014 Since the publication of this article, the authors have identified an error within Figure 2, namely that two accession numbers for the clones in panel d (a phylogenetic tree) were incorrect.
Erratum: Variation in gut microbial communities and its association with pathogen infection in wild bumble bees (Bombus)
Authors: Cariveau Daniel P , Elijah Powell J , Koch Hauke , Winfree Rachael , Moran Nancy A
Published: November 2014

Correction to: The ISME Journal (2014) 8, 2369–2379; doi:10.1038/ismej.2014.68; published online 24 April 2014 Since the publication of this article, the authors have identified incorrectly presented results in their paper. These relate to the absolute numbers of bacteria present in the gut communities of the three host species.
The Dichotomy of Memantine Treatment for Ischemic Stroke: Dose-Dependent Protective and Detrimental Effects
Authors: Trotman Melissa , Vermehren Philipp , Gibson Claire L , Fern Robert
Published: November 2014

Excitotoxicity is a major contributor to cell death during the acute phase of ischemic stroke but aggressive pharmacological targeting of excitotoxicity has failed clinically. Here we investigated whether pretreatment with low doses of memantine, within the range currently used and well tolerated for the treatment of Alzheimer's disease, produce a protective effect in stroke. A coculture preparation exposed to modeled ischemia showed cell death associated with rapid glutamate rises and cytotoxic Ca2+ influx. Cell death was significantly enhanced in the presence of high memantine concentrations. However, low memantine concentrations significantly protected neurons and glia via excitotoxic cascade interruption. Mice were systemically administered a range of memantine doses (0.02, 0.2, 2, 10, and 20 mg/kg/day) starting 24 hours before 60 minutes reversible focal cerebral ischemia and continuing for a 48-hour recovery period. Low dose (0.2 mg/kg/day) memantine treatment significantly reduced lesion volume (by 30% to 50%) and improved behavioral outcomes in stroke lesions that had been separated into either small/striatal or large/striatocortical infarcts. However, higher doses of memantine (20 mg/kg/day) significantly increased injury. These results show that clinically established low doses of memantine should be considered for patients ‘at risk’ of stroke, while higher doses are contraindicated.
Delayed Reperfusion Deficits after Experimental Stroke Account for Increased Pathophysiology
Authors: Burrows Fiona E , Bray Natasha , Denes Adam , Allan Stuart M , Schiessl Ingo
Published: November 2014

Cerebral blood flow and oxygenation in the first few hours after reperfusion following ischemic stroke are critical for therapeutic interventions but are not well understood. We investigate changes in oxyhemoglobin (HbO2) concentration in the cortex during and after ischemic stroke, using multispectral optical imaging in anesthetized mice, a remote filament to induce either 30 minute middle cerebral artery occlusion (MCAo), sham surgery or anesthesia alone. Immunohistochemistry establishes cortical injury and correlates the severity of damage with the change of oxygen perfusion. All groups were imaged for 6 hours after MCAo or sham surgery. Oxygenation maps were calculated using a pathlength scaling algorithm. The MCAo group shows a significant drop in HbO2 during occlusion and an initial increase after reperfusion. Over the subsequent 6 hours HbO2 concentrations decline to levels below those observed during stroke. Platelets, activated microglia, interleukin-1α, evidence of BBB breakdown and neuronal stress increase within the stroked hemisphere and correlate with the severity of the delayed reperfusion deficit but not with the ΔHbO2 during stroke. Despite initial restoration of HbO2 after 30 min MCAo there is a delayed compromise that coincides with inflammation and could be a target for improved stroke outcome after thrombolysis.
Hypertension Fails to Disrupt White Matter Integrity in Young Or Aged Fisher (F44) Cyp1a1Ren2 Transgenic Rats
Authors: Holland Philip R , Pannozzo Mercede A , Bastin Mark E , McNeilly Allison D , Ferguson Karen J , Caughey Sarah , Jansen Maurits A , Merrifield Gavin D , Marshall Ian , Mullins John J , Wardlaw Joanna M , Sutherland Calum , Horsburgh Karen
Published: November 2014

Hypertension is linked with an increased risk of white matter hyperintensities; however, recent findings have questioned this association. We examined whether hypertension and additional cerebrovascular risk factors impacted on white matter integrity in an inducible hypertensive rat. No white matter hyperintensities were observed on magnetic resonance imaging either alone or in conjunction with ageing and high-fat diet. Aged hypertensive rats that were fed a high-fat diet had moderately reduced fractional anisotropy in the corpus callosum with no overt pathological features. Herein we show that moderate hypertension alone or with additional risk factors has minimal impact on white matter integrity in this model.
Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism
Authors: Kim Hyunho , Xu Hangxue , Yao Qin , Li Weizhe , Huang Qiong , Outeda Patricia , Cebotaru Valeriu , Chiaravalli Marco , Boletta Alessandra , Piontek Klaus , Germino Gregory G. , Weinman Edward J. , Watnick Terry , Qian Feng
Published: November 2014

Primary cilia contain specific receptors and channel proteins that sense the extracellular milieu. Defective ciliary function causes ciliopathies such as autosomal dominant polycystic kidney disease (ADPKD). However, little is known about how large ciliary transmembrane proteins traffic to the cilia. Polycystin-1 (PC1) and -2 (PC2), the two ADPKD gene products, are large transmembrane proteins that co-localize to cilia where they act to control proper tubular diameter. Here we describe that PC1 and PC2 must interact and form a complex to reach the trans-Golgi network (TGN) for subsequent ciliary targeting. PC1 must also be proteolytically cleaved at a GPS site for this to occur. Using yeast two-hybrid screening coupled with a candidate approach, we identify a Rabep1/GGA1/Arl3-dependent ciliary targeting mechanism, whereby Rabep1 couples the polycystin complex to a GGA1/Arl3-based ciliary trafficking module at the TGN. This study provides novel insights into the ciliary trafficking mechanism of membrane proteins.
Development and application of loop-mediated isothermal amplification for detection of the F167Y mutation of carbendazim-resistant isolates in Fusarium graminearum
Authors: Duan Yabing , Zhang Xiaoke , Ge Changyan , Wang Yong , Cao Junhong , Jia Xiaojing , Wang Jianxin , Zhou Mingguo
Published: November 2014

Resistance of Fusarium graminearum to carbendazim is caused by point mutations in the β2-tubulin gene. The point mutation at codon 167 (TTT → TAT, F167Y) occurs in more than 90% of field resistant isolates in China. To establish a suitable method for rapid detection of the F167Y mutation in F. graminearum, an efficient and simple method with high specificity was developed based on loop-mediated isothermal amplification (LAMP). A set of four primers was designed and optimized to specially distinguish the F167Y mutation genotype. The LAMP reaction was optimal at 63°C for 60 min. When hydroxynaphthol blue dye (HNB) was added prior to amplification, samples with DNA of the F167Y mutation developed a characteristic sky blue color after the reaction but those without DNA or with different DNA did not. Results of HNB staining method were reconfirmed by gel electrophoresis. The developed LAMP had good specificity, stability and repeatability and was suitable for monitoring carbendazim-resistance populations of F. graminearum in agricultural production.
Leptin induced GRP78 expression through the PI3K-mTOR pathway in neuronal cells
Authors: Thon Mina , Hosoi Toru , Yoshii Michiko , Ozawa Koichiro
Published: November 2014

Leptin is a circulating hormone that plays a critical role in regulating energy expenditure and food intake. Evidence to suggest the involvement of endoplasmic reticulum (ER) stress in the development of obesity is increasing. To adapt against ER stress, cells trigger the unfolded protein response (UPR). The 78 kDa glucose-regulated protein (GRP78) is an ER chaperone that protects cells against ER stress by inducing protein folding. In the present study, we hypothesized that leptin may activate UPR and protect against ER stress associated with obesity. SH-SY5Y, a human neuroblastoma cell line stably transfected with the Ob-Rb leptin receptor (SH-SY5Y-ObRb), was treated with leptin. We demonstrated that leptin induced GRP78 expression. We then validated the mechanism responsible for the leptin-induced expression of GRP78. Interestingly, leptin-induced GRP78 expression was not dependent on IRE1-XBP1 pathway. On the other hand, the PI3K inhibitor, LY294002 and mTOR inhibitor, rapamycin, inhibited the leptin-induced expression of GRP78. These results suggested that the leptin-induced expression of GRP78 may be dependent on the PI3K-mTOR pathway. Leptin specifically induced GRP78 because the induction of the ER-apoptotic marker, CHOP, was not detected in leptin-treated cells. Therefore, leptin may upregulate the expression of GRP78, thereby protecting against ER stress associated with obesity.
Blood-brain Barrier (BBB): An Overview of the Research of the Blood-brain Barrier Using Microfluidic Devices
Authors: van der Meer Andries D. , Wolbers Floor , Vermes Istvãn , van den Berg Albert
Published: November 2014

The blood-brain barrier (BBB) is a unique feature of the human body, preserving brain homeostasis and preventing toxic substances entering the brain. However, in various neurodegenerative diseases, the function of the BBB is disturbed. Mechanisms of the breakdown of the BBB are incompletely understood and therefore a realistic model of the BBB is essential. This chapter highlights the anatomy and physiology of the BBB and gives an overview of the current available in vitro models to study the BBB in detail. Proof-of-concept work of BBB-on-Chips is described. Additionally, examples are given to optimize the present devices by engineering the microenvironment to better mimic the in vivo situation. This combination of biomedical science and micro-engineering will generate exciting new results in the field of neurovascular biology.
The Use of Microfluidic-based Neuronal Cell Cultures to Study Alzheimer's Disease
Authors: Meissner Robert , Renaud Philippe
Published: November 2014

Alzheimer's disease (AD) affects more than 35 million people worldwide and no treatment is currently available to stop neuronal decline in the brain. Microfluidics represents a promising approach to overcome limitations of conventional cell culture (1) for the establishment of in vivo-like ordered and polarized three-dimensional cell cultures and (2) for their use as alternatives to animals to study the disease progression from one part of the neuronal network to another. This chapter highlights how microtechnology-based neuroscience research opens new avenues to a thorough understanding of AD and how it may help to find answers to fundamental AD-related questions such as why pathological proteins (Tau, Aβ) spread all over the brain in a predictable pattern. Those insights potentially provide us with the necessary knowledge for the development of drug targets that counteract the dreadful consequences of this disease.
Isolation and Characterization of Circulating Tumor Cells
Authors: Yang Yoonsun , Terstappen Leon W. M. M.
Published: November 2014

Circulating tumor cells (CTCs) are tumor cells shed into the peripheral blood of cancer patients. The increasing number of treatment options for patients with metastatic carcinomas has created a concomitant need for new methods to establish which therapy will be effective and to monitor their use. Detection and characterization of CTCs is important not only to guide therapy, but also to increase our fundamental understanding of tumor progression and the formation of distant metastasis in which CTCs play a crucial role. However, identification of CTCs is quite challenging and different definitions lead to a large variation of CTC counts that will have different clinical implications. Here we will review the challenges in defining a CTC and data that have been obtained using CTCs in clinical studies emphasizing their importance as a prognostic and predictive biomarker. Furthermore, we summarize reported microfluidic platforms for CTC isolation, enumeration, and characterization developed to overcome technical challenges with current CTC detection platforms.
Fabrication of fluorescent SiO2@zeolitic imidazolate framework-8 nanosensor for Cu2+ detection
Authors: Song Yonghai , Hu Dongqin , Liu Fenfen , Chen Shouhui , Wang Li
Published: November 2014

The formation of core–shell SiO2@ZIF-8 nanostructures for Cu2+ detection is reported here.
Enantioselective transformation of Na2SO3into allylic sulfonic acids under Pd catalysis
Authors: Liu Wei , Zhao Xiao-ming , Zhang Hong-bo , Zhang Liang
Published: November 2014

Pd-catalyzed asymmetric allylic sulfonation of di-aryl-substituted allylic acetates with sodium sulfite (Na2SO3) was accomplished under mild conditions. This method directly provided allylic sulfonic acids in up to excellent yield and enantioselectivity.
Efficient 2-sulfolmethyl quinoline formation from 2-methylquinolines and sodium sulfinates under transition-metal free conditions
Authors: Xiao Fuhong , Chen Shuqing , Chen Ya , Huang Huawen , Deng Guo-Jun
Published: November 2014

An efficient approach for 2-sulfolmethyl quinoline formation from 2-methylquinolines and sodium sulfinates is described.
The small molecule probe PT-Yellow labels the renal proximal tubules in zebrafish
Authors: Sander Veronika , Patke Shantanu , Sahu Srikanta , Teoh Chai Lean , Peng Zhenzhen , Chang Young-Tae , Davidson Alan J.
Published: November 2014

The fluorescent compound PT-Yellow is a novel tool to label the proximal tubule cells of the zebrafish kidneyin vivo.
ESR spectroscopy for monitoring the photochemical and thermal degradation of conjugated polymers used as electron donor materials in organic bulk heterojunction solar cells
Authors: Frolova Lyubov A. , Piven Natalia P. , Susarova Diana K. , Akkuratov Alexander V. , Babenko Sergey D. , Troshin Pavel A.
Published: November 2014

ESR spectroscopy was applied for monitoring the degradation of conjugated polymers used in organic solar cells and comparing their stability.
Saccharides and temperature dual-responsive hydrogel layers for harvesting cell sheets
Authors: Guo Bingbing , Pan Guoqing , Guo Qianping , Zhu Caihong , Cui Wenguo , Li Bin , Yang Huilin
Published: November 2014

A novel non-invasive approach for harvesting cell sheets was demonstrated just by adding saccharide biomolecules into cell culture medium and without reduction of the temperature.
Continuous synthesis of graphene sheets by spray pyrolysis and their use as catalysts for fuel cells
Authors: Zou Biao , Wang Xiao Xia , Huang Xin Xin , Wang Jian Nong
Published: November 2014

N-doped graphene sheets were synthesized by spray pyrolysis and studied for catalyst applications.
Water-soluble nickel-bis(dithiolene) complexes as photothermal agents
Authors: Mebrouk Kenny , Chotard Florian , Goff-Gaillard Catherine Le , Arlot-Bonnemains Yannick , Fourmigué Marc , Camerel Franck
Published: November 2014

Pegylated nickel-bis(dithiolene) complexes can efficiently convert NIR light into heat in water to induce cell death.
3-Pyrrolyl-oxindoles as efficient nucleophiles for organocatalytic asymmetric synthesis of structurally diverse 3,3′-disubstituted oxindole derivatives
Authors: Cui Bao-Dong , You Yong , Zhao Jian-Qiang , Zuo Jian , Wu Zhi-Jun , Xu Xiao-Ying , Zhang Xiao-Mei , Yuan Wei-Cheng
Published: November 2014

An organocatalytic asymmetric reaction of 3-pyrrolyl-oxindoles to nitroalkenes was developed to afford a range of 3-pyrrolyl-3,3′-disubstituted oxindoles in excellent yields.
The photoformation of a phthalide: a ketene intermediate traced by FSRS
Authors: Fröbel Sascha , Buschhaus Laura , Villnow Torben , Weingart Oliver , Gilch Peter
Published: November 2014

Femtosecond stimulated Raman spectroscopy, transient absorption and quantum chemistry are combined to unravel the complex path of phthalide photoformation.
Alginate electrodeposition onto three-dimensional porous Co–Ni films as drug delivery platforms
Authors: García-Torres J. , Gispert C. , Gómez E. , Vallés E.
Published: November 2014

Three-dimensional porous Co–Ni films/alginate hybrid materials have been successfully prepared by electrodeposition to be used as a steerable magnetic device for drug delivery applications.
A facile one-pot method to synthesize a three-dimensional graphene@carbon nanotube composite as a high-efficiency microwave absorber
Authors: Wang Lei , Huang Ying , Li Chao , Chen Junjiao , Sun Xu
Published: November 2014

A novel three-dimensional graphene@carbon nanotube (CNT) composite has been prepared using a facile one-pot pyrolysis strategy using urea as the carbon source.
Silica-based nanoparticles: a versatile tool for the development of efficient imaging agents
Authors: Caltagirone Claudia , Bettoschi Alexandre , Garau Alessandra , Montis Riccardo
Published: November 2014

In this review a selection of the most recent examples of imaging techniques applied to silica-based NPs for imaging is reported.
Mesoporous zirconium phosphonate materials as efficient water-tolerable solid acid catalysts
Authors: Lin Xiu-Zhen , Ren Tie-Zhen , Yuan Zhong-Yong
Published: November 2014

Mesoporous zirconium phosphonate materials were fabricated as efficient water-tolerable solid acid catalysts.
Pillared metal organic frameworks for the luminescence sensing of small molecules and metal ions in aqueous solutions
Authors: Liu Fu-Hong , Qin Chao , Ding Yan , Wu Han , Shao Kui-Zhan , Su Zhong-Min
Published: November 2014

Two pillared-layer MOFs as luminescent probes with multifunctional sensitivities to detect metal ions and small molecules were reported. Our results show that the luminescence intensities of 1a and 2a are highly sensitive to Fe3+ and Cd2+ ions and small molecules such as acetone and nitrobenzene.
A “click-chemistry” approach for the synthesis of porphyrin dyads as sensitizers for dye-sensitized solar cells
Authors: Nikolaou Vasilis , Angaridis Panagiotis A. , Charalambidis Georgios , Sharma Ganesh D. , Coutsolelos Athanassios G.
Published: November 2014

Two novel porphyrin dyads consisting of two zinc-metallated porphyrin units, linked by 1,2,3-triazole containing bridges, have been synthesized via “click” reactions, and used as sensitizers in DSSCs.
Amorphous Co3O4 modified CdS nanorods with enhanced visible-light photocatalytic H2-production activity
Authors: Yuan Jielin , Wen Jiuqing , Gao Qiongzhi , Chen Shangchao , Li Jiaming , Li Xin , Fang Yueping
Published: November 2014

Amorphous Co3O4 modified CdS nanorods exhibit a significantly enhanced photocatalytic activity for H2 production.
Electronic structure of β-RbSm(MoO4)2and chemical bonding in molybdates
Authors: Atuchin V. V. , Aleksandrovsky A. S. , Chimitova O. D. , Diao Cheng-Peng , Gavrilova T. A. , Kesler V. G. , Molokeev M. S. , Krylov A. S. , Bazarov B. G. , Bazarova J. G. , Lin Zheshuai
Published: November 2014

Microcrystals of orthorhombic rubidium samarium molybdate, β-RbSm(MoO4)2, have been fabricated by solid state synthesis atT= 450 °C, 70 h, and atT= 600 °C, 150 h.
A metal–organic framework route to in situ encapsulation of Co@Co3O4@C core@bishell nanoparticles into a highly ordered porous carbon matrix for oxygen reduction
Authors: Xia Wei , Zou Ruqiang , An Li , Xia Dingguo , Guo Shaojun
Published: November 2014

MOF-derived Co@Co3O4@C core@bishell nanoparticles encapsulated into a highly ordered porous carbon matrix show very high catalytic activity and stability toward the oxygen reduction reaction.
A comprehensive review of sodium layered oxides: powerful cathodes for Na-ion batteries
Authors: Han Man Huon , Gonzalo Elena , Singh Gurpreet , Rojo Teófilo
Published: November 2014

The room temperature Na-ion secondary battery has been under focus lately due to its feasibility to compete against the already well-established Li-ion secondary battery.
Chronic caffeine treatment enhances the resilience to social defeat stress in mice
Authors: Yin Yong-Qin , Zhang Chun , Wang Jian-Xin , Hou Jia , Yang Xu , Qin Jing
Published: November 2014

Strong evidence has shown that caffeine exerts antidepressant-like effects in chronic stress situations by increasing dopamine levels.
Silica functionalized sulphonic acid coated with ionic liquid: an efficient and recyclable heterogeneous catalyst for the one-pot synthesis of 1,4-dihydropyridines under solvent-free conditions
Authors: Sharma Pankaj , Gupta Monika
Published: November 2014

Silica supported sulphonic acid catalysts were prepared and coated with ionic liquid, and their catalytic activities were evaluated for the one-pot synthesis of 1,4-dihydropyridines.
Simultaneous preparation of cellulose nanocrystals and micron-sized porous colloidal particles of cellulose by TEMPO-mediated oxidation
Authors: Peyre Jessie , Pääkkönen Timo , Reza Mehedi , Kontturi Eero
Published: November 2014

TEMPO-mediated oxidation of microgranular cellulose results in particles of three different length scales: cellulose nanocrystals as well as small (μm) and larger (tens of μm) porous particles with high charge density.
Metal organic frameworks CAU-1 as new photocatalyst for photochemical vapour generation for analytical atomic spectrometry
Authors: Jia Jia , Long Zhou , Zheng Chengbin , Wu Xi , Hou Xiandeng
Published: November 2014

CAU-1 MOFs was used as a new photocatalyst for Se-containing photochemical vapor generation from Se(vi) for its ultrasensitive detection by atomic fluorescence spectrometry.
Integration of reverse transcriptase loop-mediated isothermal amplification with an immunochromatographic strip on a centrifugal microdevice for influenza A virus identification
Authors: Jung J. H. , Park B. H. , Oh S. J. , Choi G. , Seo T. S.
Published: November 2014

In this paper, we demonstrated an integrated centrifugal microdevice which could perform reverse transcriptase loop-mediated isothermal amplification and immunochromatographic strip based amplicon analysis for rapid, sensitive, and multiplex influenza A virus detection.
Visualization and characterization of interfacial polymerization layer formation
Authors: Zhang Yali , Benes Nieck E. , Lammertink Rob G. H.
Published: November 2014

A microfluidic device is designed and used to investigate interfacial polymerization film formation in situ.
Rheometry-on-a-chip: measuring the relaxation time of a viscoelastic liquid through particle migration in microchannel flows
Authors: Del Giudice Francesco , D'Avino Gaetano , Greco Francesco , De Santo Ilaria , Netti Paolo A. , Maffettone Pier Luca
Published: November 2014

A novel method to estimate the relaxation time of viscoelastic fluids, down to milliseconds, is here proposed.
Mass transfer in the biomolecular binding of a target against probe molecules on the surface of microbeads sequestered in wells in a microfluidic cell
Authors: Leary Thomas F. , Manafirasi Setareh , Maldarelli Charles
Published: November 2014

The mass transfer of a target biomolecule against a library of surface probes to identify binding partners is studied in a microfluidic screening platform consisting of microbeads sequestered in wells and displaying probes on their surface.
Predicting the subcellular localization of mycobacterial proteins by incorporating the optimal tripeptides into the general form of pseudo amino acid composition
Authors: Zhu Pan-Pan , Li Wen-Chao , Zhong Zhe-Jin , Deng En-Ze , Ding Hui , Chen Wei , Lin Hao
Published: November 2014

Mycobacterium tuberculosis is a bacterium that causes tuberculosis, one of the most prevalent infectious diseases.
Correction: Rapidly improved determination of metabolites from biological data sets using the high-efficient TransOmics tool
Authors: Zhang Aihua , Zhou Xiaohang , Zhao Hongwei , Guan Yu , Zou Shiyu , Yan Guang-li , Ma Chung Wah , Liu Qi , Wang Xijun
Published: November 2014

Correction for ‘Rapidly improved determination of metabolites from biological data sets using the high-efficient TransOmics tool’ by Aihua Zhang et al., Mol. BioSyst., 2014, 10, 2160–2165.
Cytotoxic peptide conjugates of dinuclear arene ruthenium trithiolato complexes
Authors: Giannini Federico , Bartoloni Marco , Paul Lydia E. H. , Süss-Fink Georg , Reymond Jean-Louis , Furrer Julien
Published: November 2014

Novel dinuclear arene ruthenium trithiolato complexes containing a water-soluble peptide moiety in one of the three thiolato bridges were designed and evaluated against A2780 human ovarian cancer cells and against their cisplatin-resistant mutant A2780cisR.
A thermal diode and novel implementation in a phase-change material
Authors: Pallecchi E. , Chen Z. , Fernandes G. E. , Wan Y. , Kim J. H. , Xu J.
Published: November 2014

The development of devices suitable for heat management requires materials whose thermal properties and synthesis are well controlled.
Reply to the comment on “The ultrastructure of type I collagen at nanoscale: large or small D-spacing distribution?” by J. Wallace, Nanoscale, 2015, 7, DOI: 10.1039/c4nr03160a
Authors: Su Hai-Nan , Xie Bin-Bin
Published: November 2014

Measuring D-spacing values from collagen fibrils or collagen fascicles with surface curvatures will introduce additional errors. This error might be minimized by studying single collagen fibrils which are parallel to the surface of substrates.
Topical gene silencing by iontophoretic delivery of an antisense oligonucleotide–dendrimer nanocomplex: the proof of concept in a skin cancer mouse model
Authors: Venuganti, Venkata Vamsi K. , Saraswathy Manju , Dwivedi Chandradhar , Kaushik Radhey S. , Perumal Omathanu P.
Published: November 2014

Topical iontophoretic delivery of a dendrimer–antisense oligonucleotide nanocomplex demonstrates the potential for developing gene silencing therapy for skin diseases.
Assembly of RNA nanostructures on supported lipid bilayers
Authors: Dabkowska Aleksandra P. , Michanek Agnes , Jaeger Luc , Rabe Michael , Chworos Arkadiusz , Höök Fredrik , Nylander Tommy , Sparr Emma
Published: November 2014

The assembly of nucleic acid nanostructures with controlled size and shape has large impact in the fields of nanotechnology, nanomedicine and synthetic biology.
Modulation of the charge transfer and photophysical properties in non-fused tetrathiafulvalene-benzothiadiazole derivatives
Authors: Pop Flavia , Seifert Sabine , Hankache Jihane , Ding Jie , Hauser Andreas , Avarvari Narcis
Published: November 2014

Stille and Sonogashira coupling strategies allowed the preparation of luminescent TTF-benzothiadiazole donor–acceptor compounds with direct linkage or an acetylenic spacer.
Formal fluorine atom transfer radical addition: silver-catalyzed carbofluorination of unactivated alkenes with ketones in aqueous solution
Authors: Zhu Lin , Chen He , Wang Zijia , Li Chaozhong
Published: November 2014

Using a combination of ketones and Selectfluor to mimic α-fluoroketones, formal fluorine-atom-transfer radical addition (F-ATRA) reactions were successfully developed in high efficiency.
Regio- and enantio-selective oxidation of diols by Candida parapsilosis ATCC 7330
Authors: Sivakumari Thakkellapati , Chadha Anju
Published: November 2014

Optically pure (S)-diols and their corresponding hydroxy ketones were preparedviaregio- and enantio-selective oxidation of the corresponding diols using whole cells ofCandida parapsilosisATCC 7330.
Several ionic organic compounds as positive electrolyte additives for a vanadium redox flow battery
Authors: Wang Gang , Chen Jinwei , Xu Yadong , Yan Bichen , Wang Xueqin , Zhu Xuejing , Zhang Yu , Liu Xiaojiang , Wang Ruilin
Published: November 2014

Several ionic organic compounds have been employed as additives of the V(v) electrolyte for a vanadium redox flow battery (VRB) to improve its stability and electrochemical activity.
A novel process to prepare a thin silica shell on the PDDA-stabilized spherical Au nanoparticles assisted by UV light irradiation
Authors: Hang Lifeng , Li Cuncheng , Zhang Tao , Li Xinyang , Wu Yanchun , Men Dandan , Liu Guangqiang , Li Yue
Published: November 2014

The monodispersed PDDA-stabilized Au nanospheres can be coated with a thin silica shell assisted by UV light irradiation.
Synthesis, antimalarial activity, heme binding and docking studies of 4-aminoquinoline–pyrimidine based molecular hybrids
Authors: Kumar Deepak , Khan Shabana I. , Tekwani Babu L. , Ponnan Prija , Rawat Diwan S.
Published: November 2014

A series of novel 4-aminoquinoline–pyrimidine hybrids was synthesized and evaluated for their antimalarial activity.
Cinchonidine thiourea catalyzed asymmetric addition of phenols to oxindole derivatives
Authors: Kaur Jasneet , Kumar Akshay , Chimni Swapandeep Singh
Published: November 2014

A highly enantioselective Friedel–Crafts reaction of phenols with isatin derivatives catalyzed by Cinchona-derived thiourea provides biologically important 3-aryl-3-hydroxy-2-oxindoles in good to excellent yield with enantioselectivity up to 92% ee.
Study on the Atherton–Todd reaction mechanism
Authors: Mitova V. , Koseva N. , Troev K.
Published: November 2014

A new mechanism of the Atherton–Todd reaction is discussed. The first step of the reaction between diesters of H-phosphonic acid and carbon tetrachloride in the presence of a base is a salt formation between carbon tetrachloride and the base [amine·Cl]+CCl3−. The trichloromethanide anion [CCl3−] deprotonates dialkyl H-phosphonate to form chloroform and dialkyl phosphonate anion [(RO)2P(O)]−. The latter anion reacts with the chlorine cation to furnish dialkyl chlorophosphate.
Graphene-iron oxide nanocomposite (GINC): an efficient catalyst for ammonium perchlorate (AP) decomposition and burn rate enhancer for AP based composite propellant
Authors: Dey Abhijit , Athar Javaid , Varma Pankaj , Prasant Hima , Sikder Arun K. , Chattopadhyay Santanu
Published: November 2014

Development of a facile and ecofriendly route for the synthesis of GINC, followed by characterization and evaluation in propellants for missiles.
The size and structure of selected hydrated ions and implications for ion channel selectivity
Authors: Yang Zhong-Hua
Published: November 2014

The structures of hydrated sodium (yellow) and potassium (red) ions.
Porous carbon quantum dots: one step green synthesis vial-cysteine and applications in metal ion detection
Authors: Xiao Deli , Pan Renfeng , Li Siqiao , He Jia , Qi Man , Kong Sumei , Gu Yu , Lin Rui , He Hua
Published: November 2014

A bottom-up and wet-chemical method employing l-cysteine as a precursor has been proven to be an effective strategy for producing fluorescent porous CQDs.
Ionic liquid-assisted hydrothermal synthesis of Bi2WO6–reduced graphene oxide composites with enhanced photocatalytic activity
Authors: Lv Hua , Liu Yumin , Hu Jiayuan , Li Zijin , Lu Yan
Published: November 2014

Due to the synergistic contributions of graphene and ionic liquid, the as-prepared RGO–Bi2WO6 samples exhibited the remarkably enhanced photocatalytic activities under visible light irradiation.
A rapid fluorescence detecting platform: applicable to sense carnitine and chloramphenicol in food samples
Authors: Wang Ming-Hui , Gu Jiun-An , Mani Veerappan , Wu Yung-Chao , Lin Yu-Jen , Chia Yu-Ming , Huang Sheng-Tung
Published: November 2014

A new long-wavelength latent florescent probe, termed “BCC” for sensitive determination of coenzyme A, carnitine and chloramphenicol.
One-pot synthesis of photoluminescent carbon nanodots by carbonization of cyclodextrin and their application in Ag+ detection
Authors: Hu Meng , Yang Yu , Gu Xiaoyu , Hu Yang , Huang Jian , Wang Chaoyang
Published: November 2014

A simple one-pot approach was developed for synthesis of photoluminescent carbon nanodotsfromcyclodextrins.
Thiophene-based push–pull chromophores for small molecule organic solar cells (SMOSCs)
Authors: Malytskyi Volodymyr , Simon Jean-Jacques , Patrone Lionel , Raimundo Jean-Manuel
Published: November 2014

A concise review on small molecules organic solar cells based on π-conjugated thiophene scaffolds.
Large-scale synthesis of mesoporous carbon microspheres with controllable structure and nitrogen doping using a spray drying method
Authors: Li Xu , Zhou Jianguo , wang Jitong , Qiao Wenming , Ling Licheng , Long Donghui
Published: November 2014

A low-cost and high-throughput spray drying method was developed to produce mesoporous carbon microspheres with controllable structure and nitrogen doping. The obtained microspheres have spherical morphology, controllable nitrogen doping (0–7 wt%) and large mesopores.
Effect of collagen sponge incorporating Macrotyloma uniflorum extract on full-thickness wound healing by down-regulation of matrix metalloproteinases and inflammatory markers
Authors: Muthukumar Thangavelu , Prakash Dharmalingam , Anbarasu Kannan , Kumar Baskar Santhosh , Sastry Thotapalli Parvathaleswara
Published: November 2014

Collagen sponge (CS) was prepared using fish scales, which are a biological waste product in the marine food industry.
Heterogeneous Pd catalysts supported on silica matrices
Authors: Opanasenko Maksym , Štěpnička Petr , Čejka Jiří
Published: November 2014

Features, advantages and limitations associated with palladium catalysts deposited over various siliceous supports in different types of practically useful organic transformations are reviewed.
Porous cerium dioxide hollow spheres and their photocatalytic performance
Authors: Yuan Saisai , Zhang Qitao , Xu Bin , Jin Zhengyuan , Zhang Ya , Yang Yin , Zhang Ming , Ohno Teruhisa
Published: November 2014

Uniform-sized and monodiperse cerium dioxide porous hollow spheres (CeO2-PH) based on the Ostwald ripening process were fabricated by a simple solvothermal method in the absence of any templates.
Diagnosis of the measurement inconsistencies of carbon-based electrocatalysts for the oxygen reduction reaction in alkaline media
Authors: Shin Dongyoon , Jeong Beomgyun , Choun Myounghoon , Ocon Joey D. , Lee Jaeyoung
Published: November 2014

An optimal catalyst testing methodology that could allow precise benchmarking to obtain standardized ORR activity is put forward.
A biodegradable thermosensitive hydrogel with tuneable properties for mimicking three-dimensional microenvironments of stem cells
Authors: Mellati Amir , Dai Sheng , Bi Jingxiu , Jin Bo , Zhang Hu
Published: November 2014

Chitosan-g-poly(N-isopropylacrylamide) was synthesized as a stem cell mimicking microenvironment. Solubility and gel mechanical strength were optimised through manipulating the grafting parameters.
Four-component reaction of N-alkylimidazoles(N-alkylbenzimidazoles), dialkyl but-2-ynedioate, N-alkylisatins and malononitrile
Authors: Yang Fan , Zhang Li-Juan , Yan Chao-Guo
Published: November 2014

Convenient synthesis of complex spirooxindolesviafour-component reactions ofN-alkylimidazoles(N-alkylbenzimidazoles), dialkyl but-2-ynedioate,N-alkylisatins and malononitrile.
The high capacity and excellent rate capability of Ti-doped Li2MnSiO4as a cathode material for Li-ion batteries
Authors: Wang Min , Yang Meng , Ma Liqun , Shen Xiaodong
Published: November 2014

Ti-doped Li2Mn1−xTixSO4samples exhibit superior rate capability. Even at a higher rate (2 C) the samples keep a discharge capacity of around 700 mA h g−1, whereas the undoped sample only delivers a discharge capacity ofca.5 mA h g−1.
(DHQD)2PHAL ligand-accelerated Cu-catalyzed azide–alkyne cycloaddition reactions in water at room temperature
Authors: Ali Abdul Aziz , Chetia Mitali , Saikia Prakash J. , Sarma Diganta
Published: November 2014

In this work, a novel green protocol has been developed for CuAAC reactions involving (DHQD)2PHAL and CuI as catalyst system. The method is very quick, highly efficient and environmentally friendly for the synthesis of 1,2,3-triazoles.
Direct C–H amination and C–H chloroamination of 7-deazapurines
Authors: Sabat Nazarii , Klečka Martin , Slavětínská Lenka , Klepetářová Blanka , Hocek Michal
Published: November 2014

Selective methods for Pd and Cu-catalyzed C–H aminations and chloroaminations of 7-deazapurines were developed.
Production of partially reduced graphene oxide nanosheets using a seaweed sap
Authors: Sharma Mukesh , Mondal Dibyendu , Das Arun Kumar , Prasad Kamalesh
Published: November 2014

Graphene oxide nanosheets were obtained by the partial reduction of graphene oxide using a sap extracted from the red seaweed Kappaphycus alvarezii.
Pyrene nanoparticles as a novel FRET probe for detection of rhodamine 6G: spectroscopic ruler for textile effluent
Authors: Bhopate Dhanaji P. , Mahajan Prasad G. , Garadkar Kalyanrao M. , Kolekar Govind B. , Patil Shivajirao R.
Published: November 2014

The hydrophobic force of interaction between R6G and SDS stabilized PyNPs involving FRET was demonstrated by measuring fluorescence of nanoparticles as a function of concentration of R6G.
pH and reduction dual responsive cross-linked polyurethane micelles as an intracellular drug delivery system
Authors: Yu Shuangjiang , He Chaoliang , Lv Qiang , Sun Hai , Chen Xuesi
Published: November 2014

pH- and reduction-responsive disulfide-crosslinked polyurethane micelles (CL-PUMs) were developed. The CL-PUMs remained stable in normal PBS while selectively swelled or decomposed in response to weakly acidic environment or reducing agent.
Stereoselective Lewis base catalyzed formal 1,3-dipolar cycloaddition of azomethine imines with mixed anhydrides
Authors: Hesping Lena , Biswas Anup , Daniliuc Constantin G. , Mück-Lichtenfeld Christian , Studer Armido
Published: November 2014

Pyrazolidinones with a tetrahydroisoquinoline core are obtained with excellent diastereocontrol and high enantioselectivity. Theoretical studies give insight on the reaction mechanism.
How soft repulsion enhances the depletion mechanism
Authors: Rovigatti Lorenzo , Gnan Nicoletta , Parola Alberto , Zaccarelli Emanuela
Published: November 2014

Asymmetric soft binary mixtures experience a much enhanced depletion attraction if compared with the Asakura--Oosawa (AO) model. We show that soft mixtures cannot be mapped onto hard systems and hence soft depletion is not a mere extension of the widely used AO potential.
Carbon-coated, methanol-tolerant platinum/graphene catalysts for oxygen reduction reaction with excellent long-term performance
Authors: Song Wenya , Chen Zhongxin , Yang Chao , Yang Ziping , Tai Jiapo , Nan Yulong , Lu Hongbin
Published: November 2014

The carbon coating (∼2 nm thick) on Pt/graphene catalysts improved their long-term performance and methanol tolerance for ORR, and exhibited comparable catalytic activity to Pt/C catalyst. The latter could be further improved by >7 times during cycling tests under O2.
Novel cathode-supported hollow fibers for light weight micro-tubular solid oxide fuel cells with an active cathode functional layer
Authors: Meng Xiuxia , Yang Naitao , Gong Xun , Yin Yimei , Ma Zi-Feng , Tan Xiaoyao , Shao Zongping , Liu Shaomin
Published: November 2014

Micro-tubular SOFCs have the potential to become light-weight portable auxiliary power units for aircraft or spacecraft.
Facile one-pot synthesis of Pd–PEDOT/graphene nanocomposites with hierarchical structure and high electrocatalytic performance for ethanol oxidation
Authors: Yue Ruirui , Wang Huiwen , Bin Duan , Xu Jingkun , Du Yukou , Lu Wensheng , Guo Jun
Published: November 2014

Pd–PEDOT/graphene nanocomposites with hierarchical structure and superior electrocatalytic performance toward ethanol oxidation are fabricated by a facile one-pot method.
CuInSe2 and CuInSe2–ZnS based high efficiency “green” quantum dot sensitized solar cells
Authors: Li Wenjie , Pan Zhenxiao , Zhong Xinhua
Published: November 2014

The CISe-based QDs with ZnS alloy configuration exhibit higher superior optoelectronic properties and chemical stability, and thus the fabrication of CISe–ZnS QDSCs shows better photovoltaic performance.
Rational design of a highly efficient Pt/graphene–Nafion® composite fuel cell electrode architecture
Authors: Xia Zhangxun , Wang Suli , Jiang Luhua , Sun Hai , Qi Fulai , Jin Jutao , Sun Gongquan
Published: November 2014

Newly designed electrode architecture based on Pt/graphene–Nafion® composite macroporous scaffold demonstrating ultra-high Pt utilization and superior fuel cell performance is presented.
Correlation between electroconductive and structural properties of proton conductive acceptor-doped barium zirconate
Authors: Han Donglin , Shinoda Kozo , Sato Shigeo , Majima Masatoshi , Uda Tetsuya
Published: November 2014

Thulium imparts BaZrO3 with the highest proton conductivity. A good correlation exists between proton conductivity and the chemical expansion effect as a result of the incorporation of protons.
Photoelectrochemical production of useful fuels from carbon dioxide on a polypyrrole-coated p-ZnTe photocathode under visible light irradiation
Authors: Won Da Hye , Chung Jaehoon , Park Sung Hyeon , Kim Eun-Hee , Woo Seong Ihl
Published: November 2014

As a photocathode material for fuel generation from CO2 in the photoelectrochemical system, a polypyrrole coated p-ZnTe photocathode was developed and it revealed an appreciable CO2 reduction performance without any significant overpotential loss under visible light irradiation.
Chitosan-modified silver@ruthenium hybrid nanoparticles: evaluation of physico-chemical properties and bio-affinity with sialic acid
Authors: Veerapandian Murugan , Zhu X. X. , Giasson Suzanne
Published: November 2014

A hybrid nanoparticle system composed of silver, ruthenium and chitosan for selective recognition of sialic acid based on fluorescence quenching.
Synthesis and nonvolatile memristive switching effect of a donor–acceptor structured oligomer
Authors: Wang Cheng , Liu Gang , Chen Yu , Li Run-Wei , Zhang Wenbin , Wang Luxin , Zhang Bin
Published: November 2014

Self-rectified memristive behavior and nonlinear transmission characteristics were for the first time observed in a highly soluble all-conjugated oligomer. The novel electrical response of the device is arising from electric field-induced charge transfer interaction in the donor–acceptor structured oligomer.
Optically active cyclic compounds based on planar chiral [2.2]paracyclophane: extension of the conjugated systems and chiroptical properties
Authors: Gon Masayuki , Morisaki Yasuhiro , Chujo Yoshiki
Published: November 2014

Optically active propeller-shaped cyclic compounds based on planar chiral [2.2]paracyclophane emit intense and bright circularly polarized luminescence (CPL).
Dispersion and self-orientation of gold nanoparticles in sol–gel hybrid silica – optical transmission properties
Authors: Lundén H. , Liotta A. , Chateau D. , Lerouge F. , Chaput F. , Parola S. , Brännlund C. , Ghadyani Z. , Kildemo M. , Lindgren M. , Lopes C.
Published: November 2014

An original method for surface modification of metal nanoparticles and insertion in sol–gel monoliths is reported. The optical characterizations show the particle self-orientation in the bulk.