bluuebunny/crossref_metadata_2025 huggingface dataset:
MODULATING EFFECTS OF IL-4, IL-10 AND IL-13 ON THE COURSE OF PLASMODIUM BERGHEI MALARIA INFECTION IN MICE
Authors: Chin Voon Kin , WC Chong , H Haniza , Basir Rusliza
Published: April 2022

Background: Inflammation is a crucial process driving pathogenesis in malaria infection. The devastating effects of malaria infection has always been associated with severe inflammation whilst protective effect is linked to provocation of anti-inflammation responses. IL-4, IL-10 and IL-13 are well-established anti-inflammatory cytokines with their functional roles during malaria infection remain elusive. Therefore, this study was undertaken to study the effects of modulating IL-10, IL-4 and IL-13 on the course of malaria infection in Plasmodium berghei ANKA (PbA)-infected murine model. Methods: Male ICR mice were randomly assigned into 5 different groupings and were infected intraperitoneal with 0.2 mL of 2 x 107 pRBCs containing P. berghei ANKA (PbA). Malaria-infected mice were treated with recombinant mouse IL-4 (rmIL-4), recombinant mouse IL-10 (rmIL-10) and recombinant mouse IL-13 (rmIL-13) for 4 consecutive days after the establishment of the infection. The survival and parasitemia levels of malarial mice and malarial mice under different treatments were monitored. Major affected organs (kidneys, lungs, brain, liver and spleen) were subjected to histopathological analysis at day-5 post infection. Results: Our findings revealed that the overall lifespan of malarial mice treated with recombinant mouse rmIL10, rmIL-4 and rmIL-13 were prolonged, accompanied with significant reduction in malaria parasitemia levels, in particular in malarial mice receiving recombinant rmIL-10 and rmIL-13. Histopathological conditions of kidneys, lungs, brain, liver and spleen treated with recombinant mouse rmIL-10, rmIL-4 and rmIL-13 were also improved. Sequestration of parasitized red blood cells (pRBCs) and inflammation seen in major affected organs were alleviated. Conclusion: Despite some limitations, this preliminary study demonstrated the promising therapeutic effects of IL-10 and IL-13 as adjuvant therapies in reducing severe pathological manifestations triggered by inflammation during malaria infection.
RAPID IDENTIFICATION OF RUPTURED ABDOMINAL AORTIC ANEURYSM USING POINT-OF-CARE ULTRASOUND IN THE EMERGENCY DEPARTMENT: A CASE REPORT
Authors: Muhamed Amin Siti Nur Izni Sheik , Shen Kevin Wong Chuing , Ismail Ahmad Khaldun
Published: April 2022

A ruptured abdominal aortic aneurysm (AAA) is a catastrophic cardiovascular emergency which carries high risk of morbidity and mortality. Clinical manifestation includes severe abdominal pain, back or flank pain, syncope, hypotension, gastrointestinal bleeding and cardiovascular collapse. Misdiagnosis is often due to atypical presentation and results in fatal consequences. Rapid diagnosis of ruptured AAA is essential because it influences the patient’s prognosis. Timely and accurate diagnosis can be made in the Emergency Department using point-of-care ultrasound (POCUS) which has high sensitivity and specificity. We report a case of an elderly male who came with non-specific abdominal pain to the Emergency Department. Timely diagnosis of ruptured AAA was made with POCUS. The diagnosis was made by a non-radiologist using POCUS, however, the decision for ruptured AAA repair was only made by surgical team following computed tomography scan of the abdomen.
VELHICE TRANS
Authors: Viana André Sampaio , Lima Marcus Antônio Assis
Published: April 2022

Neste cenário de pandemia, a senilidade, a velhice, a terceira idade, enfim, qualquer que seja a denominação dessa fase da vida, ganharam destaque, principalmente, nos primeiros meses da COVID-19. Nesse contexto, não devemos esquecer dos desafios enfrentados, mesmo nos denominados tempos “normais”, por aqueles que se identificam como transidosos, aqui, vistos como parcela minoritária da população que merece efetivo reconhecimento. Para enriquecer essa reflexão, buscaram-se trechos do livro Velhice Transviada, de João W. Nery, que aborda sua trajetória até chegar a ser transvelho, em que, também, deu voz, através de entrevistas, a outras pessoas transidosas. Os pontos abordados por Nery nesta obra fundamentarão a análise do direito ao reconhecimento, como desdobramento de princípios constitucionais, e da importância da interdisciplinaridade entre Direito e Literatura para um olhar queer na hermenêutica jurídica.
O PAPEL DO PROCESSO METONÍMICO NO CONTEXTO DA LINGUÍSTICA COGNITIVA NA CRIAÇÃO DE CATEGORIAS CONCEITUAIS
Authors: Sperandio Natalia Elvira
Published: April 2022

Este artigo propõe uma discussão teórica acerca do papel assumido pelo processo metonímico no contexto da cognição humana na construção conceitual de categorias ordinárias. Todo debate foi construído com o intuito de ratificar o argumento construído pelos estudiosos no âmago da Linguística Cognitiva, a saber, que a metonímia, além de ser um processo básico da categorização humana, é fundamental e imprescindível na criação de categorias. Logo, pautado em uma metodologia bibliográfica, com um corpus constituído por expressões corriqueiras, chegamos à conclusão de que o processo metonímico tem seu valor subestimado pelo fato de ser confundida com outro importante processo cognitivo, a metáfora
A VALORAÇÃO EM ATIVIDADES DE LEITURA DO GÊNERO TIRINHA EM LIVRO DIDÁTICO DA EJA
Authors: Gumieiro Vieira Flávia , Malinoski Pianaro Angelo Cristiane
Published: April 2022

RESUMO:Este trabalho, que faz parte de uma pesquisa de mestrado em andamento, tem como corpus de pesquisa atividades de leitura do Livro Didático de Língua Portuguesa “Caminhar e transformar” (FERREIRA, 2013), destinado ao público da Educação de Jovens e Adultos – EJA, anos finais do ensino fundamental. Para este trabalho foram selecionadas as atividades de leitura do gênero tirinha, presentes na unidade “Trabalho e transformação” do LD. A pesquisa configura-se como qualitativa de caráter documental. Para tanto, o estudo tem como fundamentação os conceitos dialógicos do Círculo de Bakhtin, principalmente no que diz respeito à valoração. Com a análise buscou-se compreender de que maneira as axiologias sociais integram as propostas de leitura do LD no gênero tira, assim como apresentar possíveis ampliações das perguntas de leitura, as quais visam favorecer um olhar mais crítico em relação à sociedade e permitir aos alunos da EJA emitir suas contrapalavras aos enunciados.
"DEVERIA TER PERGUNTADO SEU NOME"
Authors: Malloy Letícia
Published: April 2022

Este artigo objetiva analisar o conto “Swimming Lessons”, do escritor indiano Rohinton Mistry, a partir de dois eixos temáticos: o processo de envelhecimento feminino, que, combinado a expressões de sexualidade, é observado com repulsa, e a velhice, contemplada, em momento inicial, com desprezo, e posteriormente avistada como aspecto incontornável da condição humana. Reflete-se, também, sobre o modo como aqueles eixos temáticos afiguram-se decisivos à organização da estrutura narrativa do conto, aqui examinada a partir de premissas de composição propostas por Edgar Allan Poe em “A filosofia da composição”, publicado em 1846. A análise e a interpretação do texto literário se valem de perspectivas teóricas desenvolvidas por Simone de Beauvoir (1070) e Susan Sontag (1972).
REFLECTING ON ENGLISH TEACHING AT AN EARLY AGE IN THE CHILEAN CONTEXT
Authors: Escobar Cid Pilar , Jara Quezada Gloria , Díaz Larenas Claudio
Published: April 2022

Little is known about teaching English to young learners in Chile. Despite the importance given by the Chilean government to the English subject, its instruction is not compulsory until 5th grade. Although the Ministry of Education designed optional Planes y Programas to teach English from pre-schoolers to fourth graders, this material might not necessarily meet the students and teachers’ communicative needs. This article aims to understand and compare the Chilean NT2 considering education professionals, their training, and authorities'’ guidelines and the context to what the literature has explored on the area of early childhood education, from young learners’ features to classroom environment. Final considerations and reflections are included in relation to what can be improved
É MELHOR JAIR DESACOSTUMANDO
Authors: Alves Cecília Noronha Braz , Almeida Maria de Fátima
Published: April 2022

Este presente artigo tem o objetivo de investigar a construção do estilo no discurso antivacina do presidente da República do Brasil Jair Bolsonaro, em postagens de seu perfil oficial do Facebook. Para isso, vamos mobilizar categorias, noções e conceitos da Teoria Dialógica da Linguagem como palavra, enunciado, relações dialógicas, interação verbal, estilo e gêneros do discurso. Os dois principais teóricos que vão respaldar nossa micro tese são Valentin Volóchinov (2017, 2019) e Mikhail Bakhtin (2002, 2011, 2012, 2016).
A ALEGORIA DE ULUME
Authors: Schmitz Jéssica
Published: April 2022

No âmbito dos estudos pós-coloniais, as literaturas africanas em língua portuguesa têm recebido destaque justamente por dar voz àqueles que durante longo período viveram em um silêncio imposto pela política colonialista. As literaturas africanas, por meio de escritores como Pepetela, por exemplo, têm desempenhado o papel de re(construir) e (re)organizar a historicidade das ex-colônias. Como campo de análise, utilizou-se a narrativa “Parábola do Cágado Velho”, de Pepetela, objrtivando estabelecer uma relação de sentido entre a história e a memória e, assim, verificar como se dá a representação dos eventos da história, bem como, a construção da memória, identidade e sua relação com o silêncio.
DIVULGAÇÃO DA ASTRONOMIA PARA O PÚBLICO VIDENTE E COM DEFICIÊNCIA VISUAL: EXPERIÊNCIA EM UM ESPAÇO NÃO FORMAL DE ENSINO/APRENDIZAGEM
Authors: Jesus Diego Santos de , Anastácio Simone Aparecida Fernandes
Published: April 2022

Este artigo apresenta um trabalho desenvolvido por estudantes do curso de licenciatura em Física cujo objetivo foi elaborar e realizar uma exposição voltada à divulgação da Astronomia para o público vidente e não vidente. O trabalho foi desenvolvido na disciplina de Instrumentação para o Ensino de Física III em parceria com o Museu de História Natural do Sul do Estado do Espírito Santo (MUSES). O material foi desenvolvido sob orientação da professora e com a colaboração de uma professora do Atendimento Educacional Especializado (AEE) para alunos com deficiência visual de uma escola da rede pública. De forma geral, público vidente demonstrou interesse pela exposição, principalmente com relação às maquetes dos foguetes e ao um vídeo em Realidade Virtual. A criança visitante não vidente se sentiu bem à vontade quanto ao material, mas demonstrou estranheza quanto à maquete da superfície da Lua. O visitante não vidente adulto demonstrou uma maior facilidade em manipular o material e compreender as informações, pois perdeu a visão na adolescência e tinha conhecimento inicial sobre o tema e memória visual. O visitante adolescente com baixa visão avaliou positivamente os materiais informando que os textos, imagens e maquetes permitiam compreender o que estava sendo informado.
A LEITURA NA EDUCAÇÃO INFANTIL: UM ESTUDO DAS PRÁTICAS DE ENSINO DE PROFESSORAS DE ESCOLAS DA ZONA RURAL DE ESTREITO – MARANHÃO
Authors: Alves Regysane Botelho C , Barros Cleonilde Aguiar de
Published: April 2022

O objetivo do trabalho é analisar as práticas de ensino de leitura de professoras da Educação Infantil de escolas localizadas na zona rural do munícipio de Estreito – MA. Para a geração de dados desta pesquisa qualitativa, foram realizadas entrevistas semiestruturadas com quatro professoras com experiência em salas de Educação Infantil da zona rural do referido município. O roteiro das entrevistas buscou dados sobre a realidade do trabalho dessas professoras, abordando suas práticas de leitura e sua percepção e avaliação sobre o trabalho desenvolvido. Os resultados evidenciam que elas usam textos de gêneros diversificados, em atividades lúdicas e que promovem a autonomia das crianças. Além disso, verificamos que, apesar da falta de recurso e de apoio das famílias, as professoras reconhecem a contribuição do trabalho com leitura nessa etapa da educação básica.
FORMAÇÃO CONTINUADA DE PROFESSORES DE QUÍMICA: ESTRATÉGIAS PARA O PLANEJAMENTO DE UMA AULA INCLUSIVA PARA ALUNOS COM BAIXA VISÃO
Authors: Conceição Larissa da Fonseca , Santos Gil Luciano Guedes dos , Santos Fabiana Rodrigues dos
Published: April 2022

A Educação Inclusiva (EI) tem sido pouco discutida nas Instituições de Ensino Superior que promovem a formação de professores. No entanto, em praticamente todos os espaços educacionais existem alunos com Necessidades Educativas Especiais (NEE), incluindo aqueles com baixa visão. O objetivo dessa pesquisa foi avaliar o conhecimento e a aprendizagem dos egressos do curso de Licenciatura em Química do Centro de Formação de Professores (CFP) da Universidade Federal do Recôncavo da Bahia referente aos recursos e ao uso de materiais adaptados em sala de aula para alunos com baixa visão. A pesquisa realizada teve abordagem qualitativa, sendo desenvolvido um curso temático como estratégia metodológica. Os dados foram obtidos por meio de questionários semiestruturados e duas atividades. Os resultados indicaram que existe uma carência nas discussões sobre EI no decorrer da formação acadêmica e que a realização do curso foi importante para que os egressos pudessem entender o mecanismo de preparação e desenvolvimento de uma aula inclusiva. No geral, acreditamos que a matriz curricular do curso de Licenciatura em Química do CFP deveria disponibilizar componentes curriculares que abordassem conteúdos sobre EI, NEE e o uso de materiais adaptados para o Ensino de Química para alunos com deficiência visual e outras deficiências.
DESIGN DE ESTUDOS DE CASO HISTÓRICOS PARA AS RELAÇÕES ÉTNICO-RACIAIS: CONTRIBUIÇÕES PARA O ENSINO DE QUÍMICA
Authors: Santos Jucimara de Jesus Santos dos , Santos Paloma Nascimento dos , Cabral Patrícia Fernanda de Oliveira
Published: April 2022

Neste trabalho temos como objetivo apresentar a proposta de design de estudos de caso históricos para as Relações Étnico-Raciais para o Ensino de Química, com foco específico nas questões raciais negras, como possibilidade de modificação dos problemas apresentados nesse tipo de material didático frente ao racismo e a realidade das/dos estudantes. Para tanto, nos pautamos em trabalhos sobre as temáticas citadas e apresentamos as etapas de elaboração de um estudo de caso destinado à Educação de Jovens e Adultos, sobre o contexto histórico da pandemia do novo coronavírus e as dificuldades enfrentadas pela população negra. Além disso, elaboramos uma proposta de aplicação que pode ser utilizada por professores, a partir das adequações necessárias perante a sua prática. Destacamos a potencialidade de modificação de metodologias já conhecidas para inserção de temas de discussão imprescindíveis em aulas de química em todos os níveis de ensino.
PERSPECTIVAS E DEBATES CRÍTICOS NA FORMAÇÃO DOCENTE EM TEMPOS DESAFIADORES: UMA EXPERIÊNCIA MEDIADA
Authors: Rosenau Luciana dos Santos , Urbanetz Sandra Terezinha
Published: April 2022

Em tempos desafiadores como os que vivemos, discutir a formação docente implica pensarmos os processos educativos nas suas mais diversas perspectivas. A proposta deste artigo é problematizar a formação docente em tempos pandêmicos e pós pandêmicos, a partir do relato de uma experiência realizada em um curso de licenciatura, com o uso de recursos tecnológicos dentro da perspectiva crítica de educação. Recursos esses que foram utilizados como instrumentos de mediação e diálogo, buscando a formação ampliada dos estudantes, em meio às discussões sobre a necessidade do resgate da importância do conhecimento científico como forma de enfrentamento ao negacionismo e a desvalorização da vida em geral. Ressalta-se que as oportunidades de diálogos síncronos entre professores e estudantes foram fundamentais para propiciar o desenvolvimento do processo. Os momentos dialógicos para orientação, elaboração e discussão coletivas confirmaram a hipótese de que as tecnologias quando utilizadas de forma complexa, podem potencializar as mediações no processo de aprendizagem. O texto faz uma contextualização sobre a formação docente, discute os pressupostos dessa formação na perspectiva crítica, apresenta a experiência de formação em um curso de licenciatura no âmbito da Rede Federal de Educação, Ciência e Tecnologia e tece as considerações a respeito dos desafios enfrentados no atual cenário.
CONVERGÊNCIA ENTRE PERSPECTIVAS CRÍTICAS DA EDUCAÇÃO CIENTÍFICA, DA EDUCAÇÃO AMBIENTAL E DA EDUCAÇÃO INTERCULTURAL NA PROMOÇÃO DO ENGAJAMENTO ESTUDANTIL
Authors: Almeida Rosiléia Oliveira de , Andrade Maria Aparecida da Silva
Published: April 2022

Ao retomarmos estudos que têm se debruçado na busca de compreensão dos processos que levaram à visão da ciência como conhecimento dominante nas sociedades ocidentais modernas, constatamos que, historicamente, não se reconhece os jovens como agentes da produção de saberes válidos e legítimos diante dos desafios ambientais das suas escolas e comunidades. Visando ampliar nossa reflexão sobre as potencialidades das escolas no exercício transformador das condições socioambientais, nos dedicaremos a discutir potencialidades da convergência de perspectivas emancipatórias e críticas da educação ambiental, do ensino de Ciências e da educação intercultural na promoção do engajamento dos estudantes. Diante do exposto, consideramos que uma forma promissora de operacionalizar o conceito de escola sustentável, no que se refere à dimensão do currículo, é através da abordagem dos problemas socioambientais em uma perspectiva que aproxime a educação científica orientada para a ação sociopolítica, através uma abordagem das relações CTSA por meio do enfoque de QSCs; a educação ambiental na sua vertente emancipatória, que se apoia em uma visão mais ampla da ciência, através da superação do enfoque naturalista acrítico; e a educação intercultural, promovendo o diálogo de saberes e a problematização das relações de poder existentes entre eles.
Left-Sided Prosthetic Valve Dysfunction and Gastrointestinal Bleeding
Authors: Hussain Kifah , Kattoor Ajoe John , Liu Bolun , Parfieniuk Agata , Achebe Ikechukwu , Doukky Rami
Published: April 2022

Purpose We sought to investigate the association between
left-sided prosthetic valve dysfunction and gastrointestinal (GI)
bleeding. Methods In a retrospective cohort of patients with
left-sided prostheses, we identified those who experienced one or more
GI bleeds. The latest or chronologically closest echocardiogram to the
GI bleed was analyzed by a blinded investigator for prosthetic valve
dysfunction. Results Among 334 unique patients, 166 had aortic
prostheses, 127 had mitral prostheses, and 41 had both. A total of 58
(17.4%) subjects had GI bleeding events. Patients in the “GI
Bleed” group had higher mean ejection fraction (56±14% vs. 49±15%; P
= 0.003) and higher prevalence of hypertension, end-stage renal disease,
and liver cirrhosis compared to the “No GI Bleed” group. There
was a higher prevalence of moderate or severe prosthetic valve
regurgitation in the GI Bleed vs. No GI Bleed group (8.6% vs. 2.2%; P
= 0.027). Moderate or severe prosthetic valve regurgitation was
independently associated with GI bleeding (odds ratio, 6.18; 95%
confidence interval, 1.27-30.05; P = 0.024), after adjusting for
ejection fraction, hypertension, end-stage renal disease and liver
cirrhosis. Paravalvular regurgitation was associated with a higher
incidence of GI bleeding compared to transvalvular regurgitation (35.7%
vs. 11.9%; P = 0.044). The prevalence of prosthetic valve stenosis was
similar between the GI Bleed and No GI Bleed groups (6.9% vs. 5.8%; P
= 0.761). Conclusion In a cohort of patients with predominantly
surgically placed prosthetic valves, moderate to severe left-sided
prosthetic valve regurgitation was independently associated with GI
bleeding.
Glycine at the third position of TM3 determines the action of fluralaner on insect and rat GABA receptor
Authors: Huang Qiu Tang , Sheng Cheng Wang , Liu Gen Yan , Luo Guang Hua , Song Zi Jiao , Han Zhao Jun , ZHAO CHUN QING
Published: April 2022

BACKGROUND AND PURPOSE Fluralaner is a novel isoxazoline insecticide
with broad insect spectrum, and mainly acts on the insect GABA receptor
with unique binding action, but its molecular interaction with insect
GABA receptor has not been deeply identified on molecular level
according to its selectivity between target (insect) and non-target
(mammal) organisms. EXPERIMENTAL APPOACH The potential binding residues
(I258T and L275I in TM1; V288I, M298N, G303N and A304S in TM2; G3’M/S,
A327S, G336N, M338I and A339F in TM3; M473V and I477D in TM4) were
predicted by SYBYL-X 2.1 software, and verified respectively by the
site-directed mutagenesis and two-electrode voltage clamp (TEVC)
technique. KEY RESULTS In the 11 predicted amino acids, the G3’M has the
strongest ability to reduce the sensitivity of recombinant rice stem
borer RDL homomeric channel to fluralaner. Compared with the wild-type
(WT)-RDL, the G3’M mutation almost completely abolish the binding of
fluralaner and avermectin, but not fipronil on recombinant homomeric
channel of RDL from several orders of insects in vitro. In addition, the
M3’G on rat Mus musculus β2 improved the sensitivity of recombinant
heteromeric Mmα1β2-M3’G channel to fluralaner. Our results demonstrated
that the glycine at the third position of TM3 determines the action of
fluralaner and should be the binding site of fluralaner with RDL.
CONCLUSION AND IMPLICATIONS These results would contribute to
understanding the molecular interaction of fluralaner with RDL homomeric
channel and may be used to guide future modification of isoxazolines to
achieve highly selective control of pests with minimal effects on
non-targeted organisms.
Star-shaped poly(ε-caprolactones) with well-defined architecture as potential drug carriers
Authors: Ponjavic Marijana , Nikolic Marija , Jevtic Sanja , Jeremic Sanja , Djokic Lidija , Djonlagic Jasna
Published: April 2022

The present study reports the potential application of star-shaped poly(?-caprolactones) with different number of arms as new drug delivery matrix. Linear and star-shaped PCL ibuprofen loaded microspheres were prepared using oil-in-water (o/w) solvent evaporation technique and characterized with FTIR, DSC, XRD and SEM analysis. High yield, encapsulation efficiency and drug loadings were obtained for all microspheres. FTIR analysis revealed the existence of interactions between polymer matrix and drug, while the DSC analysis suggested that drug was encapsulated in an amorphous form. SEM analysis confirmed that regular, spherical in shape star-shaped microspheres, with diameter between 80 and 90 ?m, were obtained, while quite larger microspheres, 110 ?m, were prepared from linear PCL. The advantage of using starshaped PCL microspheres instead of linear PCL was seen from drug release profiles which demonstrated higher amount of drug released from star-shaped polymer matrix as a consequence of their branched, flexible structure. Microspheres prepared from the polymers with the most branched structure showed the highest amount of the released drug after 24 h. Finally, cytotoxicity tests, performed using normal human fibroblasts (MRC5), indicated the absence of cytotoxicity at lower concentrations of microspheres proving the great potential of star-shaped PCL systems in comparison to linear ones.
Parametric effect of the interrupted annular groove fin on flow and heat transfer characteristics of a finned circular tube heat exchanger
Authors: Lin Zhimin , Yang Ruixia , Yang Haihong , Wang Liangbi , Zhang Yongheng , Guo Anning
Published: April 2022

The influences of the geometrical parameters of interrupted annular groove fin mainly including the annular groove diameter, the groove arc length, and the fin spacing, on the fin side thermal-hydraulic characteristics of a finned circular tube exchanger were numerically investigated by actualizing the custom FORTRAN programing with SIMPLE algorithm in a non-orthogonal curvilinear co-ordinate system, and the regression formulas of average Nusselt number and friction factor with flow parameters and geometrical parameters were obtained. Compared with the referential plain fin, interrupted annular groove fin could significantly improve thermal performance under the same pumping power constraint, and Nusselt number is closely germane to the secondary flow, which implies that the fin side heat transfer is depended entirely on the secondary flow strength. For Nusselt number, the annular groove diameter and the groove arc length have positive effect, while the fin pitch, the groove circumferential and radial locations have negative effect. The dominant parameters influencing on friction factor in turn are the fin pitch, the groove radial location, and the annular groove diameter. The optimal annular groove diameter is screened, and found that the optimal annular groove diameter is closely related with Reynolds number under the same pumping power constraint, while under the same mass-flow rate constraint that is scarcely related with Reynolds number.
Analysis of external heat dissipation enhancement of oil-immersed transformer based on falling film measure
Authors: Li Yingguang , Zhou Zeru , Lin Biren , Zhang Hao , Huo Weifeng , Deng Honglei , Liu Gang
Published: April 2022

With the increase of power load, the overheating problem of oil-immersed transformer in operation cannot be ignored. Therefore, it is necessary to propose reasonable heat dissipation enhancement measure for oil-immersed transformer in operation and study the influence of the measure on the internal temperature of transformer. The heat transfer process of oil-immersed transformer is analyzed, and the air-side heat transfer coefficient is pointed out to be the important parameter limiting the heat dissipation capacity of the transformer. In order to improve heat dissipation capacity, the measures based on cooling fans and falling film are proposed and the calculation methods for the air-side heat transfer coefficient are conducted, respectively. Moreover, the top-oil temperature and hot-spot temperature under two measures are compared by the thermal-fluid coupling model of oil-immersed transformer. For the transformer operating at rated load and the ambient temperature of 25?C, after the cooling fans are adopted, the top-oil temperature and hot-spot temperature can be reduced by 22.4?C and 20.7?C, while after the falling film is adopted, the top-oil temperature and hot-spot temperature can be reduced by 31.2?C and 28.7?C, respectively. The results show that the falling film is a more effective heat dissipation enhancement measure, which can meet the higher load demand of oil-immersed transformer.
Effects of geometric parameters on fluid-flow and heat transfer in micro-channel heat sink with trapezoidal grooves in sidewalls
Authors: Zhu Qifeng , Zhu Feiyue , Fu Dianwei , Zhang Anchao , Zhang Sen
Published: April 2022

Trapezoidal grooves were arranged in channel sidewalls of the proposed micro-channel heat sinks to enhance heat transfer for cooling microelectronic systems. The 3-D numerical simulations were carried out to investigate the characteristics of fluid-flow and heat transfer in the proposed micro-channels. Field structures of thermal fluid-flow, Nusselt number, and friction factor, f, were employed to study the effects of the relative groove depth, ?, and relative grooves spacing length, ?, of trapezoidal grooves on the thermal and hydraulic performance of the proposed micro-channels. The results showed that the proposed micro-channel presented better flow and thermal performance than the smooth straight one for Re <597.74 with f/f0 < 1 and for Re >149.44 with Nu/Nu0 > 1, respectively. The thermal enhancement factor, ?, was achieved up to 1.197 with ? = 0.4 and ? = 1 for Re = 714.18. Furthermore, the relative groove depth had much more significant influence on the overall performance than the relative groove spacing length.
The importance of direct genetic testing for determining female carriers of the mutation in dystrophinopathies
Authors: Maksic Jasmina , Maksimovic Nela , Rasulic Lukas , Milankov Olgica , Marjanovic Ana , Cvetkovic Dragana , Rakocevic-Stojanovic Vidosava , Novakovic Ivana
Published: April 2022

Background/Aim. Duchenne muscular dystrophy (MD) and Becker MD are caused by mutations in the gene for dystrophin (DMD). They are X chromosome-linked recessive diseases where males are affected, and females are healthy carriers of the mutation in most cases. It is estimated that 2/3 of mothers of Duchenne MD probands are carriers, while 1/3 of probands have de novo mutations. The aim of the study was to confirm the carrier status of female members of the families of Duchenne MD/Becker MD probands using direct genetic testing methods. Methods. The study included 38 females from 31 families of Duchenne MD/Becker MD probands with deletion/duplication in the DMD gene. Moreover, 4 cases of prenatal diagnosis of Duchenne MD/Becker MD were included. The methods of polymerase chain reaction - PCR and the multiplex ligation-dependent probe amplification - MLPA were applied for detecting deletions, i.e., deletion/duplication mutations in the DMD gene. Results. In the total of 31 Duchenne MD/Becker MD probands, 87.1% of deletions and 12.9% of duplications of one or more exons in the DMD gene were detected. Of the 29 tested mothers, mutations were found in 17 of them (14 deletions and 3 duplications). Mutations were detected in 11 (57.9%) out of 19 mothers of probands with the Duchenne MD phenotype and 6 (60%) out of 10 mothers of Becker MD probands. Furthermore, 14 (56%) out of 25 mothers were carriers in probands with deletions, and 3 (75%) out of 4 mothers were carriers in probands with duplications. In the remaining 9 other female relatives of the patients, mutations were found in 4. In prenatal diagnosis, we identified a deletion in one male and one female fetus of one single mother who was confirmed as a carrier. Conclusion. The study showed that mothers were carriers in almost 60% of sporadic cases of Duchenne MD/Becker MD with deletions and duplications. In addition, the carrier frequency tended to be higher in mothers of the probands with duplications (75%) compared to mothers of probands with deletions (56%).
The Development Of Multi-Path Adversary Analysis Tool For Vulnerability Assessment of Physical Protection Systems (MAVA)
Authors: Andiwijayakusuma D , Mardhi A , Setiadipura T , Purqon A , Suud Z
Published: April 2022

Abstract. The Physical Protection System (PPS) is an important component in each nuclear facility security aspect. We must regularly evaluate the effectiveness of PPS to ensure the system can anticipate every enemy attack; therefore, a PPS vulnerability assessment is needed. In this study, we develop a Multi-path Analysis tool for Vulnerability Assessment of PPS (MAVA) based on the Adversary Sequence Diagram (ASD) implemented in python computer code. We examined for feasibility by applying the code to a hypothetical facility (National Nuclear Research Facility - NNRF). The results of calculations compared to single-path analysis (EASI) show the advantages of MAVA, which can calculate the probability of interruption simultaneously on multi-path analysis. MAVA also predict the adversary's most vulnerable paths (MVP) with its various strategies for intrusion path. MAVA results show that multi-path calculations help analysts obtain information faster in evaluating to improve the effectiveness of PPS.
Menyelisik Penampilan Pendidik Dari Kaca Mata Siswa Dalam Pemberian Layanan Psikologis Dengan Konseling
Authors: Sumarni Sumarni , Yakub Elni
Published: April 2022

Kehadiran guru Bimbingan dan Konseling disekolah diharapkan mampu menjadi solusi dalam upaya pencegahan dan pengentasan dari permasalahan siswa. Melalui berbagai layanan yang diberikan diharapkan dapat menjembatani berbagai keadaan dan hubungan  yang kurang harmonis antara siswa dan guru BK. Keadaan yang dimaksud adalah tidak terungkapnya apa yang menjadi kebutuhan dan  harapan siswa terhadap layanan BK, serta permasalahan yang dihadapi oleh  siswa, baik yang terkait dengan bidang pribadi, sosial, belajar dan karir siswa. Penelitian ini bertujuan untuk memperoleh gambaran tentang hal-hal yang menjadi perhatian siswa dan yang paling berkesan bagi siswa dari penampilan guru BK dalam memberikan layanan psikologis dengan konseling.Metode penelitian yang digunakan adalah penelitian deskriptif kuantitatif dengan metode survei. Populasi dan sampel dari penelitian ini adalah seluruh siswa SMP N 45 Pekanbaru dan seluruh siswa SMP N 21 Pekanbaru sebanyak 1120 siswa. Instrument yang digunakan adalah kuesioner. Dan data yang diperoleh akan dianalisa dengan cara mencari prosentase dari setiap jawaban responden terhadap setiap butir soal. Hasil penelitian ini menunjukkan bahwa keseluruhan responden di SMP N 45 Pekanbaru dan di SMP N 21 Pekanbaru secara umum memiliki perhatian dan kesan yang sama tinggi terhadap aspek bahasa konselor, sikap penerimaan konselor dan manfaat materi layanan
Memahami Pandemi Covid-19 Dalam Perspektif Psikologi Sosial
Authors: Agung Ivan Muhammad
Published: April 2022

Pandemi COVID-19 menjadi fokus perhatian dunia saat ini. Penyebaran  COVID-19 terus terjadi secara cepat dan luas, yang berdampak pada kehidupan sosial manusia, salah satunya adalah psikologi dan perilaku manusia. Tulisan ini mencoba membahas pandemic COVID-19 dalam perspektif psikologi sosial, yang terdiri dari beberapa bagian. Pertama, membahas tentang pandemi psikologi, karakteirisk dan dampaknya, kedua, dampak pandemi COVID-19 pada proses kognisi, emosi dan perubahan perilaku di masyarakat. Ketiga, dinamika pengaruh sosial dan konformitas dan terakhir apa yang bisa kita lakukan dalam menghadapi COVID-19. Pandemi COVID-19 telah menyebabkan terjadi banyak bias kognisi sosial yang berpotensi mempengarusi emosi dan perubahan perilaku individu. Peran pemerintah dan perilaku kooperatif masyarakt sangat membantu dalam mengurangi penyebaran dan mitigasi  COVID-19. Implikasi dan rekomendasi akan dibahas dalam artikel ini dalam perspektif Psikologi sosial.
Model School Well-Being Sebagai Tatanan Sekolah Sejahtera Bagi Siswa
Authors: Anggreni Ni Made Sukma , Immanuel Aria Saloka
Published: April 2022

Sekolah merupakan elemen penting dalam proses perkembangan individu karena berfungsi pemilihan karir di masa mendatang dan merupakan sarana pembelajaran mengenai pengetahuan tentang peran sosial dan batasan norma. Implementasi sekolah yang baik bagi siswa masih perlu dievaluasi. Hal ini berdasarkan adanya ketidaksejahteraan yang dialami oleh remaja, yang berkaitan dengan adanya kasus kekerasan yang terjadi di sekolah. Menindaklanjuti berbagai fenomena tersebut maka sekolah perlu menciptakan atmosfir yang positif bagi perkembangan siswa. Tujuan artikel ini adalah mengkaji model kesejahteraan psikologis dengan konsep school well-being. School well-being merupakan penilaian subjektif individu terhadap sekolahnya dalam memuaskan kebutuhan individu yang terdiri dari empat aspek yaitu having (kondisi sekolah), loving (hubungan sosial), being (pemenuhan diri), dan health (kesehatan). Faktor-faktor yang mempengaruhi school well-being yaitu hubungan sosial, kontrol dan optimisme, teman dan waktu luang, volunteering, peran sosial, karakteristik kepribadan dan tujuan serta aspirasi. School well-being memberikan peranan untuk mengembangkan sikap positif selama proses belajar, dan dapat meningkatkan prestasi akademik serta menekankan pada pentingnya kesehatan mental siswa.
Kaitan Antara Pola Asuh Otoriter Terhadap Kemampuan Interpersonal yang Dimoderasi oleh Dukungan Teman Sebaya pada Remaja di Kota Bandung
Authors: Al Gifari Putra Nurfajri , Herlina Herlina
Published: April 2022

Penelitian ini bertujuan untuk mengetahui pengaruh pola asuh otoriter terhadap kemampuan interpersonal yang dimoderasi oleh dukungan teman sebaya pada remaja di Kota Bandung. Partisipan pada penelitian ini adalah (N=400, berusia 13-19 tahun tinggal Bersama orangtua, dan berdomisili di Kota Bandung) yang mengisi instrumen yang berisi alat ukur pola asuh otoriter untuk mengukur pola asuh otoriter, Interpersonal Competence Questionare (ICQ) untuk mengukur kemampuan interpersonal, dan The Social Provosion Scale untuk mengukur dukungan teman sebaya. Analasis data yang digunakan adalah analisis regresi linear untuk mengetahui pengaruh pengaruh otoriter terhadap kemampuan interpersonal dan dukungan teman sebaya terhadap kemampuan interpersonal, dan analisis regresi berganda moderasi untuk mengukur pengaruh pola asuh otoriter terhadap kemampuan interpersonal yang dimoderasi oleh dukungan teman sebaya. Hasil analisis menunjukan bahwa ada pengaruh pola asuhotori terterhadap kemampuan interpersonal sebesar -0,399 dengan nilai signifikansi 0,000. Terdapat pengaruh dukungan teman sebaya terhadap kemampuan interpersonal sebesar 0,281 dengan nilai signifikansi 0,000. Hasil analisis moderasi menunjukan bahwa dukungan teman sebaya memoderasi pengaruh pola asuh otoriter terhadap kemampuan interpersonal. Bentuk moderasi yang dihasilkan adalah dukungan teman sebaya mengurangi determinasi pengaruh pola asuh otoriter terhadap kemampuan interpersonal pada remaja di Kota Bandung
Pengembangan Perusahaan Menggunakan Diagnostik Open System
Authors: Ulumsyah Bahrul , Syuhada Muhammad Nur
Published: April 2022

Pengembangan perusahaan bertujuan untuk mengidentifikasi kemungkinan permasalahan yang terjadi sehingga dapat memetakan dinamika permasalahan di PT BM Persero, kemudian memberikan saran intervensi sesuai dengan permasalahan yang prioritas. Partisipan atau responden ditujukan pada 10 karyawan yang mewakili masing – masing golongan, teknik pengambilan responden menggunakan purposive sampling. Metode pengumpulan data yang digunakan yakni dengan teknik wawancara, observasi dan studi dokumen yang dibuat berdasarkan komponen – komponen desain tingkat organisasi (Cumings,2015). Data dianalisis secara kualitatif berdasarkan temuan masing-masing instrument terintegrasi. Bedasarkan hasil assesment dan rumusan permasalahan terdapat beberapa masalah yang menghambat perusahaan untuk meningkatkan kinerjanya, yang paling signifikan permasalahannya adalah karyawan  merasa kurang puas terhadap sistem carrier path di perusahaan, karena sistem carierr path yang terdapat diperusahaan masih belum tepat guna. Model diagnostic memberikan pemahaman dalam mengidentifikasi kondisi perusahaan, kemudian masalah yang teridentifikasi adalah melakukan intervensi berupa pemetaan kembali career lattice Perusahaan, untuk meningkatkan karir, memberikan kesempatan dan keleluasaan untuk beralih peran pekerjaan secara keseluruhan dan melakukan perpindahan lintas fungsi ke peran yang berbeda yang tidak memerlukan naik ke tingkat atau posisi yang lebih tinggi atau bahkan pada tingkat atau posisi yang sama (Cathy Benko & Molly Anderson De Joitte, 2010)
Gambaran Budaya Organisasi yang Berlandaskan Budaya Lokal
Authors: Buchari Nahya Qisthi , Wulanyani Ni Made Swasti
Published: April 2022

Budaya organisasi sangat berpengaruh terhadap perilaku dan efektivitas kinerja organisasi atau perusahaan yang mendukung tujuan-tujuan organisasi. Adanya variasi dan keanekaragaman budaya akan mewarnai variasi pola perilaku anggota organisasi tempat kebudayaan tersebut berlaku. Artikel ini bertujuan untuk menjelaskan gambaran budaya organisasi yang berlandaskan nilai lokal dengan pendekatan studi literatur. Budaya Lokal tersebut antara lain Tri Hita Karana, Budaya Jawa dan Budaya Sulawesi Selatan. Tri Hita Karana dapat didefinisikan sebagai tiga penyebab kebahagiaan yang terdiri dari komponen parahyangan, pawongan dan palemahan yang dapat diaplikasikan pada perusahaan. Budaya Jawa memiliki pandangan hidup Sinkretisme, Tantularisme dan berbagai ungkapan simbolis yang dapat mempengaruhi budaya organisasi. Nilai-nilai kearifan lokal budaya Makassar juga memiliki nilai-nilai yang berhubungan dengan budaya organisasi yaitu kepemimpinan Karaeng Galesong yang dikenal sebagai “siri” yakni berupa harga diri atau kehormatan yang timbul dari akal pikiran yang baik dari seorang pemimpin. Nilai kekerabatan juga disinyalir sebagai salah satu nilai-nilai budaya lokal yang melekat pada masyarakat Bugis-Makassar.
Tales of Healers and Doctors: Enlighted Pedagogy and Modernization in Cuban Costumbrismo
Authors: Pillado Miguel Angel
Published: April 2022

The aesthetic movement known as costumbrismo burst during the 19th in Spain and Latin America, and it did so into various modes of artistic expression such as literature, painting, and lithography. In all cases, it aimed at reflecting on the way of life in a given society e.g. its folklore, its institutions, its mannerisms, its social types, etc. The present article delves into Cuban costumbrismo to expose the way in which local writers akin to this aesthetic movement exhibit the local population in correspondence with an ongoing and much desired process of modernization. Specifically, it examines four cuadros de costumbres (sketches of manners of costumbrista nature) that focus on two historically antagonistic social types in Cuba: the médico (the doctor) and the vieja curandera (the old female healer). It demonstrates that the representations of these figures do not only synthesize—at best—the way in which Cuban costumbrista authors managed a process of social and historical change brought about by the tension between local traditions and the emergence of modern scientific discourses as civilizing measures. In doing so, it also reveals the intentions of these authors to legitimize the place of literature in a modernizing world where scientific discourses were also gradually becoming the only authorized language for studying and analysing both the individual and the social body.
Black Feminism Reflected through The Narrator’s Responses of Women Oppression In Maya Angelou’s Memoir: A Letter To My Daughter
Authors: Pertiwi Elly Santi , Rosiandani Ni Luh Putu
Published: April 2022

Any unjust situation where one group denies another group is considered as oppression. This condition is possibly initiated by groups that assume their internal attribute as superior to another group. Therefore, the groups assume they have the right to deny another group's rights. Women oppression is one of kinds of oppression. The differences in physical and biological features of a woman's body benefit men with more privilege and no responsibility to carry children. As a result, a woman is considered as not necessarily need education and career path. A movement has arisen to defense oppressed women, especially women of color, whose experiences are not represented through the mainstream feminist movement. Black feminism's distinctive perspective sees oppression as an intersection of factors. This article aims to elaborate Black feminist perspective toward women oppression in Maya Angelou’s memoir entitled A Letter To My Daughter. The oppression experienced by Black women is identified in the form of the control of Black women images and the regulation of Black women bodies. The narrator’s critical perspective toward the oppression is articulated through her action in promoting self-definition and self-valuation to Black women. Self-empowerment enables Black women to resist and oppose any forms of oppression.
Divine Parody: Ridiculing America’s Spiritual Crisis in Neil Gaiman’s American Gods
Authors: Rizaq Ahmad Wildan , Nurcahyani Eka
Published: April 2022

One of the reasons for modern man's mental disorders is a spiritual crisis. In American Gods, Neil Gaiman ridicules this condition by reviving religious, folklore, and mythological entities into new contexts. These entities, however, are simplified as merely intertextual references by most studies. In fact, the new contexts are pragmatically intended to parody American modernity in leading modern man to a spiritual crisis. This research, thus, aims to be a descriptive-analytical study that not only interprets such references through intertextual analysis but also uses pragmatic analysis to examine how the novel parodically portrays modern man's spiritual journey. Deploying Linda Hutcheon's Interpretation of Parody, the Intertextual analysis results that these mythological characters are resituated to represent marginal communities, like ex-convicts, fugitives, drifters, gangsters, immigrants, homeless, laborers, prostitutes, and relocators. While applying Jung's interpretation of the relationship between mythological archetypes and psychological traits, the pragmatic analysis suggests that the hero archetype has been reimagined to caricature modern man's spiritual journey in reconciling his conscious desire with unconscious competencies that resulting disorders in his mental. The factors that influence the hero's mental stability are manifested through the trickster characters in deceiving the hero's consciousness with secular realities, while the sage characters reinforce the hero's unconsciousness through some spiritual journeys.
Kajian eksperimental pemakaian Hidrokarbon Musicool 22 sebagai pengganti R 22 untuk mesin pengatur udara AC split terhadap konsumsi listrik
Authors: Setiawan Wahyu , Yuono Lukito Dwi , Ridhuan Kemas , Rajabiah Nurlaila
Published: April 2022

The use of synthetic refrigerant R22 has been banned by the government which can cause damage to the ozone layer causing global warming effects. temperature (ΔT°C) of the evaporator during the test time at the time of the study. The method used in this research is to vary the refrigerant R 22 and Musicool 22 with a pressure variation of 60,70,80 Psi, the size of the room studied is 3x4x2,5 m and Split AC Changhong, LG, and Panasonic with 1 PK power. Research results it can be seen that each brand of Split AC has a different effect of electricity consumption, the lowest and highest electricity consumption at a pressure of 60 and 80 Psi. Musicool 22 refrigerant is more energy efficient than R22. It can be seen that each brand of Split AC has the effect of the temperature difference (ΔT°C) of the evaporator, which differs the highest at a pressure of 60 and 80 Psi. Musicool 22 refrigerant is more suitable for LG and Changhong brands.
Egg Characteristics of Pelung Chickens in Four Different Areas in West Java, Indonesia: technical inputs for conservation
Authors: ASMARA INDRAWATI YUDHA
Published: April 2022

Egg characteristics such as egg size and egg quality affect the hatchability rate of chicken eggs. The study objective was to determine egg characteristics of Pelung chickens that are endangered chickens of Indonesia. A total of 116 eggs from Garut, Bandung, Cianjur and Sukabumi Regencies, West Java Province, Indonesia was selected using a purposive technique. The observed parameters were egg weight, egg specific gravity, and thickness of an eggshell. Data were analyzed using the nonparametric Kruskal-Wallis test followed by the post hoc Mann-Whitney U test. The former was used to determine data differences among research areas, while the latter was applied to compare data differences between the two research areas. The rank Spearman analysis was used to determine the correlation between observed parameters. The study showed that there were significant differences (p > 0.05) among research areas for all observed parameters. Egg weight and thickness of eggshell in the Sukabumi Regency were higher than other regencies, while egg specific gravity in this regency was the highest (p > 0.05). There was a significant positive correlation (p > 0.05) between observed parameters. The findings indicated variation in the rearing management system and the genetic of Pelung chickens in research areas.