bluuebunny/crossref_metadata_2025 huggingface dataset:
Perspectives of the Swiss policy towards the European Union
Authors: Tomczyk Michał
Published: June 2018

Stosunki między Szwajcariąa Unią Europejską mogą być postrzegane jako interesujące, a jednocześnie jako bezprecedensowy przykład nowej, elastycznej integracji. Mimo ponad dekady owocnej współpracy, wiele jej aspektów pozostaje kontrowersyjnymi. Problem autonomicznej adaptacji, braku możliwości wpływania na procesy decyzyjne na terytorium Wspólnot, otwarcia rynku pracy dla obywateli nowych państw członkowskich UE lub inne problemy związane z instytucjonalnym wymiarem realizacji umów. To tylko część problemów, które mogą być wymienione w tym kontekście. Można więc postawić zasadnicze pytanie: co będzie dalej? Czy ten bezprecedensowy przykład nowej formy integracji osiągnął już swoje granice? Jakie mogą być perspektywy przyszłej współpracy? Celem niniejszego artykułu jest próba znalezienia odpowiedzi na powyższe pytania. W rozważaniach uwzględniono kilka scenariuszy, będących wynikiem analizy aktualnych warunków i doświadczeń, jak również na oceny bieżącej strategii politycznej szwajcarskiego rządu. Mowa o: kontynuacji stosunków dwustronnych, przystąpieniu do Unii Europejskiej lub zawarciu umowy ramowej czy też stowarzyszenia. Scenariusze te są analizowane w celu znalezienia odpowiedzi na pytanie o najbardziej prawdopodobny przebieg przyszłych stosunków między Unią Europejską a Szwajcarią.
Anna Adamus-Matuszyńska, Piotr Dzik, Tożsamość wizualna polskich województw, miast i powiatów. Identyfikacja, prezentacja, znaczenie
Authors: Kaczmarek Filip
Published: June 2018

Anna Adamus-Matuszyńska, Piotr Dzik, Tożsamość wizualna polskich województw, miast i powiatów. Identyfikacja, prezentacja, znaczenie
Sprawozdanie z seminarium naukowego pt. Populistyczne komunikowanie polityczne Wydział Nauk Politycznych i Dziennikarstwa UAM w Poznaniu, 10–11 kwietnia 2018 r.
Authors: Halagiera Denis
Published: June 2018

Sprawozdanie z seminarium naukowego pt. Populistyczne komunikowanie polityczne Wydział Nauk Politycznych i Dziennikarstwa UAM w Poznaniu, 10–11 kwietnia 2018 r.
Unijny system relokacji w sprawozdaniach Komisji Europejskiej. Ocena i perspektywy
Authors: Potyrała Anna
Published: June 2018

26 września 2017 r. formalnie zakończył się okres obowiązywania decyzji o relokacji osób będących w oczywistej potrzebie ochrony międzynarodowej. Z przewidzianych 160 tysięcy, relokacji poddano do tego czasu nieco ponad 29 tysięcy osób. Przy zastosowaniu metody analizy prawnej oraz analizy decyzyjnej, w artykule podjęto próbę odpowiedzi na następujące pytania badawcze: (1) co było przyczyną odmowy dokonania relokacji przez niektóre państwa członkowskie?; (2) jakie działania podejmowała Komisja Europejska chcąc nakłonić państwa do wypełnienia zobowiązań prawnych?; (3) jakie konsekwencje pociąga za sobą odmowa dokonania relokacji osób, będących w potrzebie ochrony międzynarodowej?. W artykule analizie poddano cykliczne sprawozdania Komisji Europejskiej z funkcjonowania nadzwyczajnego, czasowego mechanizmu relokacji. W toku poprowadzonych rozważań wskazano przyczyny niewywiązywania się przez państwa członkowskie z prawnych zobowiązań oraz przyczyny braku woli dokonania rzeczywistej reformy polityki azylowej i imigracyjnej. Udowodniono, że wyrażone w traktatach zobowiązanie do wspólnych, solidarnych działań w obliczu kryzysów ustąpiło miejsca partykularnym dążeniom do wzmocnienia ochrony terytoriów państwowych.
Rola Frontex w zarządzaniu przestrzenią wolności, bezpieczeństwa i sprawiedliwości UE
Authors: Piechowicz Michał
Published: June 2018

Celem artykułu jest horyzontalna i funkcjonalna analiza umiejscowienia agencji Frontex w systemie instytucjonalnym UE oraz wskazanie jej znaczenia w tworzącym się ponadnarodowym systemie zabezpieczania granic. Artykuł jest próbą odpowiedzi na pytanie, czy Frontex jest nowym rodzajem instrumentu zarządzania przestrzenią wolności, bezpieczeństwa i sprawiedliwości UE? W pracy wykorzystano metody jakościowe, a za źródło informacji posłużyła analiza treści dokumentów i literatury przedmiotu. W artykule znajdują się informacje o roli i specyfice agencji ponadnarodowych, znaczeniu Frontex i usytuowania w strukturze instytucjonalnej UE, jak również o utworzonych instrumentach realizacji celów agencji tj. Eurosur i IBM. Dyskusji poddano także aspekt przenikania się sfery krajowej i ponadnarodowej w omawianym aspekcie PWBiS. Artykuł dowodzi, że pozytywnie należy zweryfikować założenie, że to tworzone na poziomie ponadnarodowym narzędzia służące realizacji celów Frontex sprzyjają procesowi uwspólnotowienia systemu zarządzania granicami zewnętrznymi UE. Wnioski wskazują także, że pomimo rozbudowywanych kompetencji wspierania zarządzania granicami na poziomie ponadnarodowym, nadal jest to kompetencja państw członkowskich, dla których nadzór granic lądowych i morskich jest sprawą priorytetową bezpieczeństwa.
Przyczyny i polityczne skutki wyborów uzupełniających do Senatu RP
Authors: Leszczyńska Krystyna
Published: June 2018

Wybory uzupełniające do Senatu RP w ocenie polskich polityków spełniają funkcję barometru odzwierciedlającego nastroje polityczne społeczeństwa. Celem artykułu jest wskazanie przyczyn i politycznych skutków wygasania mandatu senatora w trakcie kadencji. Porównując wyniki badań, uzyskane w rezultacie analizy zagadnienia określonego w tytule artykułu, podjęto próbę odpowiedzi na następujące pytania badawcze: 1) jakie czynniki wpływają na wygaśnięcie mandatu senatora w Polsce?; 2) jak kształtuje się frekwencja w tych wyborach na tle frekwencji w wyborach do Sejmu i Senatu?; 3) w jakim stopniu wybory uzupełniające do Senatu wpływają na zmianę jego kompozycji politycznej?; 4) czy stanowią one wiarygodny barometr nastrojów politycznych społeczeństwa? Zastosowane metody badawcze (instytucjonalno-prawna, statystyczna, porównawcza) pozwoliły sformułować wnioski. Dotychczas wygasło 44 mandaty senatorskie (4,9%). Głównymi przyczynami były: śmierć (36,4%), objęcie ważnych stanowisk publicznych (22,8%) i wybór na posła do PE (15,9%). Przeprowadzone 37 razy elekcje uzupełniające do Senatu z reguły wywoływały niewielkie zainteresowanie wyborców (najczęściej około 7%). Jednak zdarzało się, że ich wyniki sygnalizowały nadchodzącą zmianę polityczną (elekcje uzupełniające w IV, V i VIII kadencji) lub kontynuację istniejącego układu politycznego (elekcje uzupełniające w VI kadencji). Skuteczność tego prognostyka jest dość zawodna; okazała się trafna w czterech z siedmiu kadencji Senatu.
The Mackey problem for free locally convex spaces
Authors: Gabriyelyan Saak
Published: June 2018

It is known that the free locally convex space

L
⁢

(
X
)

{L(X)}

on a space X is metrizable only if X is finite and that

L
⁢

(
X
)

{L(X)}

is barrelled if and only if X is discrete. We significantly generalize these results by proving that

L
⁢

(
X
)

{L(X)}

is a Mackey space if and only if X is discrete. Noting that real locally convex spaces which are Mackey groups are always Mackey spaces, but that
the converse is false, it is also proved here that

L
⁢

(
X
)

{L(X)}

is a Mackey group if and only if it is a Mackey space.
A Multi-objective Approach for Supply Chain Network Design: Tilapia Pisciculture in Paraná State - Brazil
Authors: Ramos Manoel João , Sousa Fragoso Rui Manuel de , Feiden Aldi
Published: June 2018

Nowadays, efficient supply chain network design is a major issue, which becomes a greater challenge with the need to consider environmental and social concerns in decisions, besides economic issues. This paper develops a supply chain planning model based on a multi-objective framework that considers economic, social and environmental issues. The model is applied to the tilapia pisciculture supply chain in Brazil. A pay-off matrix is derived and an approximation of the Pareto frontier is built using the augmented ε-constraint method. Several non-dominated solutions are generated and analyzed in order to propose the preferable scenarios of supply chain network design.
Market Structure of the Feed Industry in Germany: Causing Asymmetric Spatial Price Transmission?
Authors: Schulte Hinrich , Musshoff Oliver
Published: June 2018

Over the last couple of years, the production amount of feed and the market concentration of the feed industry vastly increased in North-Western Germany. This development might lead to asymmetric price transmission of feed between regions in Germany because feed markets in other regions grow slower and therefore decline in relative volume and importance. To analyze this development, the objective of the study was to quantify price relationships of pig, hens and calves feed prices between Western Lower Saxony, Eastern Lower Saxony and Westphalia. Assuming Western Lower Saxony as the central market and using monthly price observation from 2007 until 2017, the results show that the feed prices were co-integrated across regions and type of feed. The results show a tendency of asymmetric price transmission for pig feed between Western Lower Saxony and Eastern Lower Saxony but this was not statistically significant at the 5 % level. Furthermore, we also tested the influence of the feed scandals dioxin in pig feed and mold in imported maize from Serbia, but we could not estimate a pattern of price adjustments between regions according to the feed scandals. Summarizing the results, we came to the conclusion that feed prices might be perfectly transmitted across regions and independently from feed scandals and type of feed.
On the power sum problem of Lucas polynomials and its divisible property
Authors: Xiao Wang
Published: June 2018

The main purpose of this paper is to use the mathematical induction and the properties of Lucas polynomials to study the power sum problem of Lucas polynomials. In the end, we obtain an interesting divisible property.
Use of cognitive enhancers among medical students in Lithuania
Authors: Lengvenyte Aiste , Strumila Robertas , Grikiniene Jurgita
Published: June 2018

Aims

The purpose of this study is to analyse the use of cognitive enhancers among medical students in Lithuania, determine the reasons for usage and evaluate the contributing factors such as socio-demographic characteristics, stress levels, sleep quality and knowing somebody who has used a neuro-enhancing drug.

Design

A cross-sectional survey study was performed by analysing a convenience sample of n=579 in the two universities offering medical education in Lithuania, Vilnius University and the Lithuanian University of Health Sciences. In 2014, students were asked to fill in anonymous paper questionnaires consisting of 13 items on prevalence of substance use to enhance cognitive performance, and on reasons and correlates (response rate 95%) during lecture time.

Results

Of the respondents, 8.1% indicated that they had used cognitive enhancers. Among those who had used these drugs, nootropics were the most frequently mentioned (59.6%), while psychostimulants, such as modafinil, methylphenidate and amphetamine-derived drugs were mentioned less frequently (38.3%). Other substances were indicated by 23.4% of the respondents. Improvement of concentration and increased studying time were predominant purposes (55.3% and 48.9% of users, respectively). Male students reported three times higher prevalence rates than females (14.6% vs. 5.1%, p<0.05). Prevalence was also higher in students who knew someone using these substances than among those who did not know such persons (17.3% vs. 5.1%, p< 0.05). This was the most associated factor with cognitive-enhancing drug-taking behaviour. No correlation between cognitive enhancement usage and sleep quality or stress levels was found, nor between usage and belonging to a student organisation or having a job.

Conclusions

In Lithuania, 1 of 12 medical students admits to having used neuro-enhancing drugs. Our study results provide an overview of the actual situation on correlates and reasons for taking performance-enhancing substances.
Collections in Early Bolzano
Authors: Centrone Stefania , Siebel Mark
Published: June 2018

There are quite a few studies on late Bolzano’s notion of a collection (Inbegriff). We try to broaden the perspective by introducing the forerunner of collections in Bolzano’s early writings, namely the entities referred to by expressions with the technical term ‘et’. Special emphasis is laid on the question whether these entities are set-theoretical or mereological plenties. Moreover, similarities and differences to Bolzano’s mature conception are pointed out.
Acute and Delayed Effects of a Resistance Training Session Leading to Muscular Failure on Mechanical, Metabolic, and Perceptual Responses
Authors: Párraga-Montilla Juan A. , García-Ramos Amador , Castaño-Zambudio Adrián , Capelo-Ramírez Fernando , González-Hernández Jorge M. , Cordero-Rodríguez Yaiza , Jiménez-Reyes Pedro
Published: June 2018

Párraga-Montilla, JA, García-Ramos, A, Castaño-Zambudio, A, Capelo-Ramírez, F, González-Hernández, JM, Cordero-Rodríguez, Y, and Jiménez-Reyes, P. Acute and delayed effects of a resistance training session leading to muscular failure on mechanical, metabolic, and perceptual responses. J Strength Cond Res 34(8): 2220–2226, 2020—This study explored the acute and delayed (24 and 48 hours after exercise) effects of a resistance training session leading to muscular failure. Eleven resistance-trained men completed a training session consisting on 3 sets of repetitions to failure during the back-squat exercise performed at the maximum possible speed with a load equivalent to a mean propulsive velocity (MPV) of 1 m·s−1 (≈60% of 1 repetition maximum). A number of mechanical (number of repetitions and starting MPV of the set, MPV achieved against the 1MPV load, countermovement jump [CMJ] height, and handgrip strength), metabolic (lactate, uric acid, and ammonia concentrations), and perceptual (OMNI-RES perceived exertion) variables were measured. The results revealed (a) a decrease of 38.7% in set 2 and 54.7% in set 3 of the number of repetitions performed compared with the first set (p < 0.05), (b) a reduction in the MPV of the repetitions and an increase in lactate concentration and OMNI-RES values with the succession of sets (p < 0.05), (c) comparable decrements in CMJ height after the 3 sets (25–32%), (d) a decrease in CMJ height (p < 0.05; 6.7–7.9%) and in the MPV attained against the 1MPV load (p < 0.05; 13–14%) after 24 and 48 hours of completing the training session, but no significant changes were observed in handgrip strength (p > 0.05; <2%), and (e) uric acid and ammonia concentrations above the basal levels (p < 0.05). The large decrements in mechanical performance together with the high metabolic stress discourage the frequent use of resistance training sessions leading to muscular failure.
Structural Engineering Test for Determining the Circumferential Modulus of Circular Pipes and Tubes
Authors: Zureick Abdul-Hamid , Bechtel Andrew J.
Published: June 2018

This article proposes a structural engineering test method for determining the transverse flexural modulus of circular tubes and pipes made from fiber-reinforced polymer composite. The computed modulus from the proposed test can be used both in the design and in the qualification and acceptance procedures of these structural components. To validate the proposed test method, experiments were conducted on 23 metallic and 4 carbon fiber-reinforced polymer composite rings having different material properties, diameters, and thicknesses. In addition, three different test setups and measurement techniques were used where each ring was subjected to two collinear tension forces while recording both the force and the change-in-diameter along the line of action of the two forces. The recorded data was then used to compute the transverse moduli of the circular tubes. The transverse modulus values determined from the proposed test were compared with those obtained from material tensile and flexural coupon tests carried out on the same tube materials. The three test setups and measurement techniques yielded satisfactory results, suggesting that the proposed test method is viable for adoption in both laboratory and field testing while balancing its ease of use and cost.
Surface Layer Characterization of Shot Peened Gear Specimens
Authors: Santa-aho Suvi , Sorsa Aki , Wartiainen Jukka , Lundin Per , Suominen Lasse , Jokiaho Tuomas , Honkanen Mari , Leiviskä Kauko , Vippola Minnamari
Published: June 2018

The production of gear components includes numerous manufacturing operations, which are carried out to ensure proper surface characteristics. Shot peening is one of the surface finishing processes used for transmission components like gears to improve their fatigue behavior. Shot peening increases the compressive residual stresses on the surface, and the procedure also reduces the amount of retained austenite in the surface layer. In addition, shot peening has an influence on other mechanical properties, such as surface roughness and surface hardness. An experimental design was conducted with varying shot peening process parameters, like coverage density and intensity, to alter the surface layer of 13 transmission gear specimens. The correlation between shot peening parameters, Barkhausen noise (BN) features, and X-ray diffraction residual stress measurement was studied. Linear correlation was found between residual stress and shot peening parameters. The relationship between residual stress and BN root-mean-square was not evident but was revealed by taking the ratio of BN measurements at different frequencies. Additionally, BN features, such as peak position, coercivity, and integral area, were found to have a linear trend with the intensity. Along with the aforementioned measurements, other material characterization measurements were also taken. The shot peening coverage density was observed to have a linear relationship with surface roughness values, while an intensity of over 0.6 mm A was noticed to affect the surface hardness. The results obtained can be used in the determination of suitable shot peening parameters to achieve a surface with desired residual stress and other surface properties.
Les colonies grecques du sud de la Gaule (VIIe – IIe s. avant n. è.)
Authors: Joncheray Claire
Published: June 2018

Le sud de la Gaule est caractérisé par la forte présence phocéenne. La colonisation de type phocéen est tardive mais c’est la seule qui se soit étendue au nord de la zone tyrrhénienne ; et c’est le phénomène le plus persistant dans sa durée, du VIIe au IIe s. av. J.-C. Cet article fait le point sur l’évolution chronologique de la présence des Grecs sur le territoire celte méditerranéen et surtout des Phocéens. Des premiers contacts, il reste quelques traces matérielles dans les nécropoles celtes du sud de la Gaule. À partir de la fondation de Marseille, vers 600 av. n. è., le paysage culturel et politique change durablement. L’article présente l’habitat de Marseille et aussi celui d’Olbia-de-Provence, une des cinq colonies de Marseille sur le littoral méditerranéen celte. Cet article intègre les interactions avec les Grecs et les transferts culturels dans l’étude des processus d’installation des Grecs.
La précolonisation : un mot pour dire l’archéologie des premiers contacts ?
Authors: Esposito Arianna
Published: June 2018

Cet article propose de revenir sur la précolonisation, une notion fondatrice de la littérature archéologique sur la colonisation grecque. On y aborde son interprétation théorique et les difficultés qui y sont liées. Concept idéologiquement très chargé, en particulier dans le cadre de la tradition d’études postcoloniales, illustrant initialement l’émulation et la rivalité entre les partisans de la thalassocratie phénicienne et les tenants de la primauté des Grecs comme civilisateurs de l’Occident, la notion de précolonisation demeure à notre sens pertinente au même titre que celle de colonisation. Les deux illustrent deux phénomènes historiquement et fonctionnellement différents, malgré l’idée de contigüité implicitement induite par le préfixe « pré- ». Cet article vise à dépasser cette idée en pointant les changements relationnels entre Grecs et autochtones imposés par la fondation des colonies et les potentiels conflits qui en résultent pour le contrôle de la terre.
Gregos e povos nativos na bacia do Mar Negro entre os séculos VIII – III A.C.
Authors: Dana Madalina
Published: June 2018

Os gregos que se instalaram nas margens do Mar Negro nos séculos VII e VI a.C. tiveram desde o início que coabitar e dividir o território com populações locais variadas, tanto nômades como sedentárias. Suas relações, nem sempre pacíficas, não eram necessariamente conflituosas, pelo menos não em todas as épocas: sobre isso, as circunstâncias históricas devem ser levadas em consideração. Seus destinos são escritos em paralelo, a critério das mudanças e dos contatos que caracterizam as regiões ditas coloniais, com especificidades locais tais como uma manifestação artística regional que pode ser chamada de arte greco-cita. Os contatos culturais são na realidade mais variados, indo desde as práticas sociais, como os casamentos mistos, às práticas religiosas e literárias.
Os atenienses fora da Ática no período clássico
Authors: Saint Pierre-Hoffmann Catherine
Published: June 2018

O vasto movimento de fundações de apoikiai da época arcaica parece quase não ter chegado até Atenas, em comparação com outras cidades como Corinto ou Mileto. As fontes são assim raras para evocar as poucas fundações atenienses da época arcaica. Por outro lado, a documentação sobre a época clássica – seja ela contemporânea ou mais tardia – enaltece a cidade da Ática, como ocorre em muitos outros assuntos. No entanto, a instalação de atenienses fora de Ática apresenta uma face bastante diferente do movimento de colonização do período arcaico – como é o caso de muitas das fundações da época clássica. Esta presença fora da cidade se insere, no caso de Atenas, em um âmbido específico. No século V a.C. a Liga de Delos (478 a.C.) permitiu a Atenas exercer uma forma de dominação sobre o território de algumas cidades aliadas. Se a derrota de Atenas em 404 a.C. marca um declínio da cidade no mundo grego, este é apenas temporário. No quarto século, antes da chegada dos macedônios, Atenas consegue se impor a muitas cidades por meio da segunda confederação de Atenas (377 a.C.). Não se trata de abordar aqui o conjunto das fundações do período clássico, mas sim de ver quais são as formas das instalações dos atenienses fora da Ática e de tentar identificar as eventuais mobilidades que isto gerou.
Mapping the Competitive Advantage of SMEs in East Java, Indonesia
Authors: Tobing Diana Sulianti K. , Fathorazz Moehammad , Wulandari Gusti Ayu
Published: June 2018

This article describes the situation and potential of SMEs in East Java Indonesia. Small and medium enterprises are essential to support the economic progress of a country. By using descriptive analysis and multiple regression then generated mapping. Mapping the characteristics and competitiveness of SMEs is done as a basis for gap analysis. If the current condition of Indonesian SMEs is known, benchmarking can be done by comparing ideal conditions or targets to be achieved in the face of global competition. The mapping generated from this research is expected to provide an overall picture of SMEs in disrict of Jember, Bondosowo, Situbondo and Banyuwangi, East Java Province, Indonesia, so that it can assist government and business actors in determining business strategies and policies. This study found the variables that significantly affect the competitive position are innovation ability, quality focus, customer loyalty, response to change, price advantage and marketing power. While the insignificant membership of the cooperative, it does not have a significant role for the creation of a strong competitive position. This is supported by the fact that most of the SMEs in eastern Java are not members of the cooperative. Similarly, business status with legal status and not and the use of intermediary traders is not a thing that affects the strength of competitive position.
Model Technology to Performance Chain (TPC) in Implementing Accrual-Based Sistem Informasi Manajemen Daerah (SIMDA) Finance: Empirical Evidence from Local Government of Indonesia
Authors: Abdillah Willy , Saepullah Asep
Published: June 2018

This study examines TPC model in the context of utilization of accrual-based SIMDA Finance version 2.7 at Local Government of Indonesia. The success of SIMDA Finance development is not only determined by how the SIMDA Finance can process quality information, but also determined by its suitability to the work environment and its user duties. This study uses 2.056 of financial administrators of Local Government Department, consisting treasury admission, spending treasury, and operator. Online questionnaire distributed by snowball sampling with 24.5 percent of response rate and examined by Partial Least Square (PLS) technique. This study found that Job Characteristics and Techology Characteristics effect on Task-Techology Fit (TTF), Utilization, and Performance Impact. Theoretically, the study found that the TPC model was able to explain the context of public sector organizations, especially government agencies in Indonesia, outside of the organizational context when the TPC model was developed and developed earlier. Practically, the implications of research findings for stakeholders of SIMDA Keuangan are discussed further.
Implication of Macroeconomic Factors to Stock Returns of Indonesian Property and Real Estate Companies
Authors: Maharditya Muhammad Adika , Layyinaturrobaniyah Layyinaturrobaniyah , Anwar Mokhamad
Published: June 2018

This study aims to identify the effect of interest rate change policy made by Bank Indonesia during the period of January 2010-March 2016 to stock return of the property sector and real estate. In addition, this study also aims to test whether fluctuations in government bond yields, inflation, and indigo exchange also affect the stock returns of the property sector and real estate in Indonesia. By using purposive sampling, there are 15 companies that will be used as research samples. By using multiple linear regression analysis, there is no significant negative effect of interest rate (BI Rate) and inflation on stock return of the property sector and real estate. Nevertheless, it was found that the variable fluctuation of government bond yield and dollar exchange rate against rupiah had a negative and significant effect on stock returns of property and real estate sector in Indonesia. Increased bond yield would make investors choose other instruments as an alternative to investing money. In addition, investors also tend to choose to save money in the form of US Dollar rather than investing money in the capital market, further with the weakening of the value of the rupiah will increase the amount of foreign debt from the company.
INT-767 prevents NASH and promotes visceral fat brown adipogenesis and mitochondrial function
Authors: Comeglio Paolo , Cellai Ilaria , Mello Tommaso , Filippi Sandra , Maneschi Elena , Corcetto Francesca , Corno Chiara , Sarchielli Erica , Morelli Annamaria , Rapizzi Elena , Bani Daniele , Guasti Daniele , Vannelli Gabriella Barbara , Galli Andrea , Adorini Luciano , Maggi Mario , Vignozzi Linda
Published: June 2018

The bile acid receptors, farnesoid X receptor (FXR) and Takeda G-protein-coupled receptor 5 (TGR5), regulate multiple pathways, including glucose and lipid metabolism. In a rabbit model of high-fat diet (HFD)-induced metabolic syndrome, long-term treatment with the dual FXR/TGR5 agonist INT-767 reduces visceral adipose tissue accumulation, hypercholesterolemia and nonalcoholic steatohepatitis. INT-767 significantly improves the hallmarks of insulin resistance in visceral adipose tissue (VAT) and induces mitochondrial and brown fat-specific markers. VAT preadipocytes isolated from INT-767-treated rabbits, compared to preadipocytes from HFD, show increased mRNA expression of brown adipogenesis markers. In addition, INT-767 induces improved mitochondrial ultrastructure and dynamic, reduced superoxide production and improved insulin signaling and lipid handling in preadipocytes. Bothin vivoandin vitrotreatments with INT-767 counteract, in preadipocytes, the HFD-induced alterations by upregulating genes related to mitochondrial biogenesis and function. In preadipocytes, INT-767 behaves mainly as a TGR5 agonist, directly activating dose dependently the cAMP/PKA pathway. However,in vitroexperiments also suggest that FXR activation by INT-767 contributes to the insulin signaling improvement. INT-767 treatment counteracts HFD-induced liver histological alterations and normalizes the increased pro-inflammatory genes. INT-767 also induces a significant reduction of fatty acid synthesis and fibrosis markers, while increasing lipid handling, insulin signaling and mitochondrial markers. In conclusion, INT-767 significantly counteracts HFD-induced liver and fat alterations, restoring insulin sensitivity and prompting preadipocytes differentiation toward a metabolically healthy phenotype.
Modified Peritoneal Dialysis for Treatment of Acute Renal Failure after Complex Congenital Heart Surgery in Infants
Authors: Zhang Lefeng , Jin Yongqiang , Zhang Fuqiang , Li Hongyin , Wu Qingyu
Published: June 2018

Background: Acute kidney injury (AKI) is one of the common complications in infants and children after complex congenital heart surgery. Peritoneal dialysis (PD) is usually applied for renal replacement therapy (RRT), especially in infants. We investigated the efficacy and safety of modified PD for the treatment of acute renal failure and congestive heart failure after cardiac surgery for congenital heart disease in infants. Methods: We retrospectively analyzed five consecutive patients from October 2015 to February 2017. The patients were aged from four days to five years old, and all had acute renal failure and congestive heart failure after cardiac surgery. In the five patients treated with modified PD (five males; average weight: 11.2 ± 5.5 kg), we used the Seldinger technique percutaneous abdominal puncture 16 G single lumen central venous catheter instead of the Tenckhoff peritoneal dialysis catheter as a PD catheter. Modified PD was intermittent. We recorded and monitored circulation and metabolism index.Results: Five cases (100%) with modified PD were restored to normal renal function. Congestive heart failure was gradually alleviated, and pulmonary and cardiovascular function were improved. Urine volume increased. Neither peritonitis nor catheter leakage occured in any of our cases. Urine volume increased due to PD, from 0.16 + 0.18 mL/kg*h before PD to 2.63 + 1.05 ml/kg*h at the end of PD (P < .05). Serum creatinine, serum urea nitrogen, and serum K+ changed from 85.0 ± 36.5 µmol/L, 17.1 ± 7.5 mmol/L, and 4.57 ± 0.30 mmol/L before PD, to 76.0 ± 36.7 µmol/L, 20.1 ± 11.0 mmol/L, and 4.42 ± 0.42 mmol/L at the end of PD, respectively (P > .05). Acidosis, hyperkalemia, hypoxemia and low cardiac output syndrome were improved. All patients were cured and discharged with normal renal function. Conclusions: We conclude that modified single lumen central venous catheter for PD is a safe, feasible, and less invasive therapeutic strategy for AKI in infants undergoing cardiac surgery, and is worthy of being widely applied in clinical practice.
Genomic Selection in Preliminary Yield Trials in a Winter Wheat Breeding Program
Authors: Belamkar Vikas , Guttieri Mary J , Hussain Waseem , Jarquín Diego , El-basyoni Ibrahim , Poland Jesse , Lorenz Aaron J , Baenziger P Stephen
Published: June 2018

Genomic prediction (GP) is now routinely performed in crop plants to predict unobserved phenotypes. The use of predicted phenotypes to make selections is an active area of research. Here, we evaluate GP for predicting grain yield and compare genomic and phenotypic selection by tracking lines advanced. We examined four independent nurseries of F3:6 and F3:7 lines trialed at 6 to 10 locations each year. Yield was analyzed using mixed models that accounted for experimental design and spatial variations. Genotype-by-sequencing provided nearly 27,000 high-quality SNPs. Average genomic predictive ability, estimated for each year by randomly masking lines as missing in steps of 10% from 10 to 90%, and using the remaining lines from the same year as well as lines from other years in a training set, ranged from 0.23 to 0.55. The predictive ability estimated for a new year using the other years ranged from 0.17 to 0.28. Further, we tracked lines advanced based on phenotype from each of the four F3:6 nurseries. Lines with both above average genomic estimated breeding value (GEBV) and phenotypic value (BLUP) were retained for more years compared to lines with either above average GEBV or BLUP alone. The number of lines selected for advancement was substantially greater when predictions were made with 50% of the lines from the testing year added to the training set. Hence, evaluation of only 50% of the lines yearly seems possible. This study provides insights to assess and integrate genomic selection in breeding programs of autogamous crops.
La calidad espermática en peces y los métodos de evaluación
Authors: López-Hernández Juan C. , Osorio Pérez Adriana , Jiménez-Félix Salvador A. , Páramo-Delgadillo Salomón , Márquez-Couturier Gabriel , Yasui George S. , Arias-Rodríguez Lenin
Published: June 2018

El efecto antrópico, la pérdida de biodiversidad, el desplazamiento de especies, la introducción de especies exóticas y el incremento demográfico, han promovido aumentar el rendimiento de los cultivos, la recuperación de sitios impactados, la reintroducción de especies y la búsqueda de alternativas para comprender, y evaluar la reproducción de las especies ícticas nativas. En ello, el conocimiento y el empleo de los gametos de hembras y machos de los peces, para la producción masiva de larvas hacen necesario el uso de metodologías que permitan seleccionar todos aquellos reproductores que muestren cualidades genéticas y fisiológicas que den pauta a mejorar e incrementar la cantidad y la calidad de las larvas que serán empleadas para cultivo masivo, repoblación, producción de reproductores y para su empleo en experimentos de ciencia básica y aplicada. En esta revisión bibliográfica, se hace mención de las particularidades de las células espermáticas de los peces y de las alternativas metodológicas para evaluar su calidad, mediante la comprensión de la fisiología de la activación (porcentajes y tiempo de motilidad, tipo de movimiento y número de espermatozoides) y hasta el análisis estructural en el nivel extracelular e intracelular (morfología espermática, daño a la membrana, ensayo cometa, células vivas/muertas/apoptóticas, mismas que están en función de los objetivos de los programas de reproducción o experimentación). Con el desarrollo de equipos de citometría automática y de genómica unicelular, se ha logrado mayor comprensión del funcionamiento de las células espermáticas, de la expresión genética ligada a las cualidades celulares y del significado biológico.
Prevention of Opioid Addiction
Authors: Tarter Ralph E. , Cochran Gerald , Reynolds Maureen
Published: June 2018

Ameliorating the factors that cause and sustain opioid addiction is essential for effective prevention. Accordingly, this discussion begins with a brief review of the etiological components, developmental pathways, and phases of addiction across the lifespan. Next, assessment of risk for addiction is discussed as to the basis of objective determination of prevention tactics. The main prevention tactics are succinctly noted. Lastly, the challenges that need to be surmounted to increase access to and success of prevention interventions are considered. Recommendations that may improve effectiveness of prevention of opioid addiction conclude this article. In particular, it is argued that successful prevention is contingent on shifting resources from the criminal justice system to the health care system.
Forgotten but Not Gone: The Impact of the Opioid Epidemic and Other Substance Use Disorders on Families and Children
Authors: Daley Dennis C. , Smith Erin , Balogh Daniel , Toscaloni Jodi
Published: June 2018

This article discusses the impact of the opioid epidemic and other substance use disorders (SUDs) on families and their members, including children. We review factors contributing to this major public health and safety problem, current trends in opioid and other substance use and misuse, prevalence of opioid use disorders (OUDs) and other SUDs, and interventions to help families. Sources of information for this article include research, clinical and recovery literature, government reports, experiences of the two senior authors in clinical settings, and interviews and surveys of family members affected by a loved one’s SUD.
The Role of Community Coordinated Efforts in Combating the Opioid Overdose Crisis: The Pennsylvania Opioid Overdose Reduction Technical Assistance Center
Authors: Mirigian Lynn S. , Pugliese Marco F. , Pringle Janice L. , Gaydos Monica F.
Published: June 2018

The Pennsylvania Opioid Overdose Reduction Technical Assistance Center (TAC) was developed by the University of Pittsburgh, School of Pharmacy, Program Evaluation and Research Unit (PERU) and funded by the Pennsylvania Commission on Crime and Delinquency (PCCD) in response to the need for local coordination and supported efforts to address the growing number of opioid overdoses in Pennsylvania. This article outlines the TAC’s initiatives to address this crisis in 42 counties across the Commonwealth of Pennsylvania, stressing the importance of communication and collaboration both within and between communities, such as public health, public safety, first responders, physicians, the criminal justice system, and families. The TAC uses the Implementation Framework (IF) developed by Dr. Janice Pringle to achieve accurate data assessment and the effective implementation, evaluation, and sustainability of programs.
Backmatter
Authors: Staff Editorial
Published: June 2018

backmatter
Linguagem na perspectiva da Psico/Neurolinguística e da Neurociência Cognitiva
Authors: Hübner Lilian Cristine , Wilson Maximiliano A. , Brambati Simona M.
Published: June 2018

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Structural and crystal-chemical characteristics of the apatite deposits from human aortic walls
Authors: Danilchenko Sergei N. , Kalinkevich Aleksei N. , Moskalenko Roman A. , Kuznetsov Vladimir N. , Kochenko Aleksandr V. , Husak Evgenia V. , Starikov Vadim V. , Liu Fuyan , Meng Junhu , Lü Jinjun
Published: June 2018

Thermal behavior of biological apatite is the object of several studies. Crystal size, carbonate content, phase composition, and other parameters change during annealing up to 900 °C in biological minerals with apatite structure. The way these parameters change reflects the specific properties of the initial bioapatite. This work presents data on thermal transformations of pathological bioapatite from the human cardiovascular system, namely aortic wall deposits. Some minor elements, foreign to calcium hydroxyapatite (e.g., Na and Mg), can be both incorporated in the apatite structure and localized in the surface layers of crystals, modifying functions of the mineral. A new approach was proposed to determine the predominant location of minor elements, such as Mg, Na, and K, in the mineral of pathological deposits. Mg and Na in pathological apatite can be in both structurally bound (substituting calcium in lattice) and labile (localized on the crystal surface) states, while K is not able to join the apatite structure in significant amount or be chemically bound to it. This approach, based on atomic spectrometry, can be used effectively in combination with a set of traditional techniques, such as like EDS, IRS, and XRD.
A search for new otomycotic species and their sensitivity to different antifungals
Authors: Ahmed Mohammed Rifaat , Abou-Halawa Ashraf Saad , Hessam Waheed F. , Abdelkader Diaa’ Salaheldin Aly
Published: June 2018

Background

Otomycosis is a common ear problem in countries with hot and humid climate. Emergence of new fungal species is a possibility particularly in patients with chronic illness or who receives antibiotics either systemically or topically.

Aim

To identify the otomycotic species, which are responsible for developing the otomycosis.

Methods

A descriptive study was carried out in 63 patients who were clinically diagnosed with otomycosis. Swabs were taken from the fungal debris to identify the causative agent and to determine the effective antifungals against it.

Results

Aspergillus species were the most common agents and were found in 47 patients (74.6%), represented by A. fumigatus (36.5%), A. niger (27%), A. flavus (6.5%), and A. terreus (4.8%). Ketoconazole (90%) and miconazole (76%) were the most effective antifungals against the species obtained from cultures, whereas fluconazole was the least effective.

Conclusions

Although there is no change in the mycology of otomycosis, there is still a significant variability in the isolated species and in their sensitivity to antifungal drugs. Ketoconazole exhibited broad spectrum effect against fungal isolates in this study, whereas fluconazole was the least efficacious.
Studi Eksploratif Mengenai Karakteristik dan Faktor Pembentuk Identitas Etnik Sunda
Authors: Rahman Agus Abdul , Sarbini Sarbini , Tarsono Tarsono , Fitriah Elis Anisa , Mulyana Agus
Published: June 2018

Jawa Barat is one of the provinces with strong cultural identity. Nowadays, several districts in West Java seek to strengthen their cultural identity in various ways. This study explores the characteristics and factors that shape the identity of Sundanese. The study was conducted in one of the districts in West Java that are intense in maintaining and developing Sundanese culture. Respondents consisted of 639 students in seventeen schools. Data were collected using questionnaires and interviews. The results show that the ethnic identity of the respondents was above average. Most respondents have reached the “achieved” stage, which is marked by strong exploration and commitment. Factors influencing the ethnic identity of respondents include gender, parent education, and the use of Sundanese as the native language. Sundanese ethnic characteristics are mentioned by many respondents, among others, polite and polite, friendly or “someah,” solider and like mutual help, compassionate, sociable, and religious.
Hubungan Religiusitas dengan Citra Tubuh pada Wanita Dewasa Awal
Authors: Sumanty Dessy , Sudirman Deden , Puspasari Diah
Published: June 2018

This research attempts to relate the body image phenomenon with the level of subject religiosity. This research used correlational research design that was involving 332 respondents. The statistical testing which is used to test the hypothesis Rank Spearman. The calculation result with the significance level of trust 95% (a = 0.05) show that the correlation coefficient is 0.083 and p-value is 0.129. It means that Ho is accepted and H1 is rejected. It can be concluded that there is no relationship between religiosity with body image.
Resiliensi pada Penyintas Banjir Ditinjau dari Tawakal dan Kecerdasan Emosi
Authors: Habibah Ridha , Lestari Subekti Dwi , Oktaviana Sherli Kurnia , Nashori Fuad
Published: June 2018

Resilience by people affected by natural disasters is very important. Disaster is an extreme thing that can make a person depressed, anxious, stressed, and somatisasi. Individuals who pay attention to belief in God, cognitive and positive affective of the things it faces, will affect its resilience. This study aims to determine the resilience of flood survivors in terms of tawakal and emotional intelligence. The research subjects were flood survivors aged 20-60 , 53 people, obtained by using quotum technique. Data collection used three psychological scales: Resilience Scale, Emotional Intelligence Scale, and Tawakal Scale. The methods for data analysis were multiple linear regression and partial correlation. The results showed significant relationship between tawakal and emotional intelligence together against resilience. The relationship between tawakal and resilience is significant but the relationship between emotional intelligence and resilience is not significant. Further analysis shows emotional intelligence has indirect relationship mediated by tawakal variable.
Microprocessors, micro computer and the probabilities of their wide applications in our country
Authors: Dieu Phan Dinh
Published: June 2018

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On two problems over polyhedral convex sets
Authors: Thieu Tran Vu
Published: June 2018

In this paper, we are concerned with the following two problems often encountered in concave programming: Given the  vertices and extreme detections of a polyhedral convex set Modefined by a system of linear constraints, determine the vertices and  extreme directions of the polyhedral convex set  obtained from M just by adding one new linear equality (or inequality) constraint.Among the constraints of a given polyhedral convex set, find those which are redundant, i.e. which can be removed without affecting the polyhedral convex set.
An approximate solution of the filtration problem of a system of the dams by the finite element method
Authors: Luoc Ngo Van , Quang Ta Hong , Luat Le Kim
Published: June 2018

Using the finite element method we construct an algorithm for solving the filtration problem of a system of dams. The program based on  this algorithm is coded in FORTRAN for the EC-1022 and MINSK-32. This program is used for solving the filtration problem of Hoa Binh dam in Viet Nam.
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Authors: - -
Published: June 2018

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Decomposition of inseparable nonlinear optimization problems by the multilevel hierarchical method
Authors: Tai Nguyen Dinh , Dieu Phan Dinh
Published: June 2018

For solving one class of nonlinear optimization problems of a large-scale stationary nonseparable system, composing N interacting subsystems has proposed a three-level algorithm based on a combination of the component descent method with the dual method. An approximate variant of this algorithm is established and the convergence of last under certain conditions is proved.
Composition of concurrency relations and marked simple nets
Authors: Thanh Hoang Chi , Proszynski Piotr
Published: June 2018

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Book Review
Authors: - -
Published: June 2018

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Cover 1
Authors: - -
Published: June 2018

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A labelling operator and relational operations
Authors: Huy Nguyen Xuan
Published: June 2018

A set of algorithms of relational operations in the realization of DBMS is described. A quantitative efficiency of these algorithms by using of labeling operator is derived.
On the selection of the regularization parameter for Hammerstein’s equation
Authors: Buong Nguyen
Published: June 2018

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3rd National Congress of mathematicians
Authors: - -
Published: June 2018

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Table of Contents
Authors: - -
Published: June 2018

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On some algorithms for the division in the relational data models
Authors: Thuy Nguyen Thanh , Huy Nguyen Xuan
Published: June 2018

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The program packages for primer information processing, identification of the dynamic characteristic, choosing optimal working regime and design of the agricultural machines
Authors: Lang Pham Van , My Nguyen Huy , Anh Nguyen Tuan , Chau Tran Minh , Hung Le Sy , Hung Nguyen Thai
Published: June 2018

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Brief
Authors: - -
Published: June 2018

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Book review
Authors: - -
Published: June 2018

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Một vài thuật toán thực hiện phép chia trong mô hình quan hệ
Authors: Thủy Nguyễn Thanh , Huy Nguyễn Xuân
Published: June 2018

tiếng Nga
Reasoning in knowledge bases with external and internal uncertainties
Authors: Dieu Phan Đinh , Que Tran Dinh
Published: June 2018

The paper presents a method of logical reasoning in knowledge bases with uncertainty; such a knowledge base is given by a set of “knowledges” of  two  following forms: 1)    where S is a sentence, and I Í[0,1] is an interval of the possible values for truth probability of S. 2)    Ù   Ù …Ù  ® , where S1, S2,…, Sn, S are sentences, and  I1, I2,…, In, I are the corresponding intervals of their truth probabilities. Let B be a  such knowledge base, and S be a goal sentence. The  interval of truth probabilities of S derived from B can be found by the  proposed method.
A formula for creation and its applications to generate plots on computers
Authors: Hai Doan Nguyen
Published: June 2018

In this paper we propose a formula for creation and present the design of a plot generation system as one application of this formula. Such a system has been implemented in our university in 1993.