bluuebunny/crossref_metadata_2025 huggingface dataset:
Trends in Human Papillomavirus-Related Health Burden in Greece from 1996 to 2021 with a Focus on Cervical and Lip, Oral Cavity, and Pharyngeal Cancer
Authors: Tampakoudis Georgios , Anastasiou Olympia E.
Published: February 2025

This study aimed to evaluate the burden of HPV-related hospitalization and mortality in Greece, with a focus on invasive cervical cancer and lip, oral cavity, and pharyngeal (LOCP) cancers. A retrospective query using data from the Greek Statistical Office and Eurostat was executed. The query included hospital admission and standardized mortality rates (SDRs) on cervical dysplasia and cervical, vulvar, and vaginal; anal; penile; and LOCP cancers. The hospitalization rate for invasive cervical cancer decreased over time, exhibiting a sharp decrease after 2010, while the hospitalization rate for LOCP cancer decreased after 2011, preceded by a sustained increase from 1996. The hospitalization rate of HPV-attributable diseases in total showed a declining tendency between 2013 and 2017. SDR due to cervical cancer showed a slightly decreasing trend in Greece and the European Union, while SDR due to LOCP cancer showed a slightly increasing trend in Greece, but a decrease in the European Union. The decline in hospitalization rates for HPV-related disease in Greece, especially for cervical cancer and dysplasia, and also the declining SDR for invasive cervical cancer in Greece and the EU, are indications of the positive public health impact of screening programs and the implementation of HPV vaccination.
Physicochemical and Sensory Evaluation of Sustainable Plant-Based Homopolymers as an Alternative to Traditional Emollients in Topical Emulsions
Authors: Meneguello Talita Ganem , Palma Nathalia Kopke , Santos Yasmin Rosa , Carvalho Ariel Figueira , Ladeira Ariane Dalan da Silva , Bonsanto Fabiana Perrechil , Andreo-Filho Newton , Lopes Patricia Santos , Benson Heather Ann Elizabeth , Leite-Silva Vania Rodrigues
Published: February 2025

Objectives: This study evaluated the potential of sustainably sourced, plant-based homopolymers derived from citronellol as an alternative to the traditional emollients used in pharmaceutical, cosmetic, and personal care products. With increasing emphasis on environmentally friendly ingredients and manufacturing processes, this study assessed the efficacy of these homopolymers in semi-solid and emulsion-based formulations. Methods: The analyses focused on physicochemical, sensory, biophysical, and neurosensory characteristics. Results: The results demonstrated that emulsions containing sustainable homopolymers maintained viscoelastic stability, preserving rheological properties over time under varying conditions. These formulations showed comparable structural and functional stability to those with traditional emollients while offering skin hydration, moisture retention, and elasticity, with reduced transepidermal water loss. Sensory evaluations highlighted positive user acceptance, with participants favoring the skin feel and in-use qualities of these emulsions over synthetic alternatives. Neurosensory analyses confirmed the strong visual appeal of the product packaging, capturing user attention effectively. Conclusions: These findings underline the capability of plant-based homopolymers to replace traditional emollients while providing significant consumer appeal and sustainability benefits. This study establishes their potential as viable components in the development of more eco-friendly topical formulations for the pharmaceutical, cosmetic, and personal care industries.
Green Product Innovation as a Mediator Between Green Market Orientation and Sustainable Performance of SMEs
Authors: Sulaiman Mohammed Ali Bait Ali
Published: February 2025

This study looks at how green market orientation affects green product innovation and the sustainable performance of SMEs in the manufacturing sector of an emerging market. Therefore, the objective of the study is to analyze the mediating role of green product innovation between green market orientation and the sustainable performance of SMEs. It also looks at how green product innovation can operate as a mediator in the relation between green market orientation and the sustainable performance of manufacturing SMEs. The data from 324 Omani manufacturing sector SMEs were analyzed using the partial least squares structural equation modeling (PLS-SEM) technique. The findings indicate that green market orientation has a direct impact on the sustainable performance of manufacturing SMEs. Furthermore, the findings suggest that green market orientation has an indirect impact on the sustainable performance of manufacturing SMEs through green product innovation, which confirms the mediating effect. Manufacturing SMEs accept responsibility for continuously improving the safety and health of their employees while focusing on innovation in new green products. This empirical study, which was examined in the context of Oman’s developing market economy, is unique as it highlights the significant mediating influence of green product innovation on the sustainable performance of manufacturing SMEs. This study complements earlier studies that have mostly been carried out in industrialized (Western) economies. Practically speaking, this study emphasizes for SMEs the importance of consistently experimenting with new concepts for sustainable innovation and a competitive edge in a tough business environment. Future research directions are also provided. Therefore, the findings recommend that the owners and managers of the manufacturing sector’s SMEs should invest in green product innovation to promote sustainable performance in accordance with green market orientation concepts.
The Application of Sewage Sludge-Derived Compost or Biochar as a Nature-Based Solution (NBS) for Healthier Soil
Authors: Jakubus Monika , Černe Marko , Palčić Igor , Pasković Igor , Ban Smiljana Goreta , Ban Dean
Published: February 2025

The present study highlights the possibility of using sewage sludge-derived compost (SSC) or biochar (SSB) as valuable organic amendments. Such utilization of sewage sludge fulfills the principles of a carbon farming and nature-based solution strategy (NBS). This study focused on a detailed analysis of quantitative and qualitative changes in soil C compounds (total carbon—TC, total organic carbon—TOC, humic substances—CHS, labile carbon—LC, and water extractable organic carbon—WEOC), which resulted from the application of SSC or SSB; an assessment of variability in total and available forms of N and S as biogenic components that are integrally related to the organic matter of the amendments used in the experiment; and an indication of the possible relationships between C compounds and available nutrients. The experiment was conducted under greenhouse conditions with terra rosa soil amended with SSC or SSB at different application rates (25, 50, 75, 100% by mass). Soil samples were analyzed for the abovementioned parameters using appropriate analytical methods. Regardless of the organic amendment, the values of tested parameters increased with the applied dose, with the differences being significantly greater in relation to the contents determined for the control soil. In general, the application of SSC was more favorable than SSB, which was manifested by 12–49-fold higher TOC, 6–24-fold higher total N, and 10–41-fold higher total S levels. An exception was found for the content of available sulfur, which was significantly higher in the soil fertilized with biochar. In addition, SSC contributed more humic acid carbon (12.5–24.15 g∙kg−1) and labile carbon (10.34–27.37 g∙kg−1). On the other hand, SSB had a greater effect on fulvic acid carbon levels (2.18–2.75 g∙kg−1), which were comparable to the levels of LC (3.44–6.86 g∙kg−1) and WEOC (2.56–6.28 g∙kg−1). The research results highlighted the validity of processing SS into compost or biochar for further use for agricultural/reclamation purposes. Despite their different impacts on the studied soil properties, both organic amendments are important for maintaining soil health and can play a significant role in carbon farming as NBS practices. The findings allow us to conclude that the strategy of increasing the amount of C through SSC or SSB fertilization is the advisable direction in sustainable soil management.
The Impact of Cooperation Network Evolution on Communication Technology Innovation: A Network Interaction Perspective
Authors: Yang Xiaomeng , Qu Sen , Kong Lingkai
Published: February 2025

Seeking inter-organisation cooperation is an important way to achieve communication technology innovation, and dynamic networked cooperation deserves more attention. The present paper aims to reveal the influence of cooperation network evolution on communication technological innovation. Based on the cooperative patent in the communications industry in China during the years 2002–2021, this paper constructs negative binomial regression models to analyse the impact of network structure and node evolution characteristics on communication technological innovation and the interaction between them. The results show that, at the level of network structure, the clustering coefficient always significantly negatively impacts technological innovation. The influence of network closure has changed from positive to negative. For network nodes, the influence of centrality on technological innovation has changed from positive to negative. The impact of structural holes is always positive. Regarding network interaction, the interaction between clustering coefficient and centrality changes from positive to negative, but the interaction with structural holes is always negative. The positive effect of network closure interacting with network node characteristics diminishes. This study can fill the research gap in network interaction and dynamic networks and provide a reference for innovative organisations to find suitable partners for promoting communication technology innovations.
Ambient Air Pollution and Parkinson’s Disease and Alzheimer’s Disease: An Updated Meta-Analysis
Authors: Xie Cuiyao , Xia Xi , Wang Kai , Yan Jie , Bai Lijun , Guo Liqiong , Li Xiaoxue , Wu Shaowei
Published: February 2025

Background: Previous epidemiological evidence regarding the associations between ambient air pollution and two major neurodegenerative diseases, Alzheimer’s disease (AD) and Parkinson’s disease (PD), remains inconclusive. Objective: This study aimed to evaluate the associations between long-term and short-term exposure to PM2.5 and PM10 (i.e., particulate matter with an aerodynamic diameter of, or smaller than, 2.5 μm or 10 μm), nitrogen dioxide (NO2), ozone, sulfur dioxide, and carbon monoxide and the risks of AD and PD. Methods: A random-effects model was used to summarize individual effect estimates in the meta-analysis. A subgroup meta-analysis was further conducted to explore the potential sources of heterogeneity. Results: In total, 42 eligible studies were included. For each 5 μg/m3 increase in long-term PM2.5 exposure, the odds ratios (ORs) were 1.16 (95% CI: 1.04, 1.30; I2 = 95%) and 1.10 (95% CI: 1.03, 1.17; I2 = 95%) for AD and PD, respectively. For each 5 μg/m3 increase in short-term PM2.5 exposure, the OR was 1.01 (95% CI: 1.002, 1.01; I2 = 77%) for PD. For each 1 ppb increase in long-term NO2 exposure, the OR was 1.01 (95% CI: 1.0002, 1.02; I2 = 79%) for PD. Conclusion: Ambient air pollution, particularly PM2.5, may contribute to the increased risks of neurodegenerative diseases including AD and PD.
Molecular Farming for Immunization: Current Advances and Future Prospects in Plant-Produced Vaccines
Authors: Vo Dang-Khoa , Trinh Kieu The Loan
Published: February 2025

Using plants as bioreactors, molecular farming has emerged as a versatile and sustainable platform for producing recombinant vaccines, therapeutic proteins, industrial enzymes, and nutraceuticals. This innovative approach leverages the unique advantages of plants, including scalability, cost-effectiveness, and reduced risk of contamination with human pathogens. Recent advancements in gene editing, transient expression systems, and nanoparticle-based delivery technologies have significantly enhanced the efficiency and versatility of plant-based systems. Particularly in vaccine development, molecular farming has demonstrated its potential with notable successes such as Medicago’s Covifenz for COVID-19, illustrating the capacity of plant-based platforms to address global health emergencies rapidly. Furthermore, edible vaccines have opened new avenues in the delivery of vaccines, mainly in settings with low resources where the cold chain used for conventional logistics is a challenge. However, optimization of protein yield and stability, the complexity of purification processes, and regulatory hurdles are some of the challenges that still remain. This review discusses the current status of vaccine development using plant-based expression systems, operational mechanisms for plant expression platforms, major applications in the prevention of infectious diseases, and new developments, such as nanoparticle-mediated delivery and cancer vaccines. The discussion will also touch on ethical considerations, the regulatory framework, and future trends with respect to the transformative capacity of plant-derived vaccines in ensuring greater global accessibility and cost-effectiveness of the vaccination. This field holds great promise for the infectious disease area and, indeed, for applications in personalized medicine and biopharmaceuticals in the near future.
Safety, Tolerability, and Immunogenicity of the Pneumococcal Vaccines PPSV23 or PCV15 Co-Administered with a Booster Dose of mRNA-1273 SARS-CoV-2 Vaccine in Healthy Adults ≥50 Years of Age
Authors: Omole Tosin , Pelayo Enrique , Weinberg Aaron S. , Chalkias Spyros , Endale Zelalem , Tamms Gretchen , Sterling Tina M. , Good Lori , Shekar Tulin , Johnson Morgan , Banniettis Natalie , Buchwald Ulrike K. , Esteves-Jaramillo Alejandra
Published: February 2025

Background/Objectives: Streptococcus pneumoniae with, or following, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been associated with increased mortality, particularly in older adults. However, vaccination can be an effective preventative measure. This Phase 3 study (NCT05158140) assessed the immunogenicity and safety of co-administering the SARS-CoV-2 vaccine mRNA-1273 with the 23-valent pneumococcal polysaccharide vaccine (PPSV23) or the 15-valent pneumococcal conjugate vaccine (PCV15). Methods: Participants were healthy adults ≥50 years of age who had previously received a two-dose primary series of mRNA-1273 ≥5 months before the first study visit and may have received a booster dose of mRNA-1273 ≥4 months prior to the first study visit. Participants were randomized (1:1:1:1) to receive mRNA-1273 concomitantly with PPSV23 or PCV15 on Day 1 followed by placebo on Day 30, or sequentially with mRNA-1273 and placebo on Day 1 and PPSV23 or PCV15 on Day 30. The primary study endpoints were pneumococcal-serotype-specific opsonophagocytic activity (OPA) geometric mean titers (GMTs) and SARS-CoV-2-specific binding antibody GMTs at 30 days after vaccination, as well as safety and tolerability following vaccination. Results: In total, 850 adults participated in the study. Serotype-specific OPA GMTs at 30 days post-vaccination with PPSV23 or PCV15 were generally comparable between the concomitant and sequential groups. SARS-CoV-2-specific GMTs increased in all groups from pre-vaccination to 30 days post-vaccination with mRNA-1273, with a consistent response between concomitant and sequential groups. Safety profiles were comparable across study groups. Conclusions: Co-administration of mRNA-1273 with PPSV23 or PCV15 in healthy adults ≥50 years of age was immunogenic and well tolerated.
Investigation of Removal Efficiency of Microplastics at Different Process Stages of a Wastewater Treatment Plant in the Textile Industry in Southern China
Authors: Zhu Yanjing , Yang Sijia , Gustavsson Mathias , Huang Wenli , Gao Si , Wang Rui
Published: February 2025

Wastewater treatment plants (WWTPs) play a crucial role in mitigating microplastic (MP) release to the environment. In this paper, a WWTP of a textile manufacturing plant in Guangdong, China, was investigated to identify MP characteristics and the effectiveness of wastewater treatment within the plant. Laser Direct Infrared (LDIR) and Liquid Chromatography with Mass Spectrometry (LC-MS/MS) were applied to quantify both the number and the mass of the microplastics in the effluent of the textile manufacturing plant where most of the wastewater were from three printing and dyeing lines. The study further investigated the MP removal efficiency of each wastewater treatment process of the industry-owned WWTP and analysed the removal mechanism of each step, highlighting limitations in detecting and eliminating MPs. It is observed that (1) the results from LDIR and LC-MS/MS can be complementary to each other; (2) the MP concentration in the influent was 1730 n/L by number and 13.52 µg/L by mass; (3) the total removal efficiency of the WWTP were 99% by the number of MPs and 67.7% by the mass of MPs; (4) nine types of polymers have been identified in the influent, of which Polyamide (PA) was dominating; (5) hydrolysis acidification removed PA most; (6) aerobic tank, sand filter, and biological aerated filter (BAF) showed low removal efficiency; (7) coagulation and sedimentation tank had the highest removal efficiency to PET than any other processes.
Control of the presence or absence of carcinogens in the production of non-food consumer goods
Authors:   LLC «Food Standards and Technologies», Russia, St. Petersburg, Fursov D. , Alexandrova A. ,   LLC R&D «Consumer Prevention», Russia, St. Petersburg
Published: February 2025

Voluntary certification of non-food consumer goods production compliance with the
conditions and standards that exclude the presence of carcinogens in finished products allows
manufacturing enterprises to reach new, safer level of production, both for workers, simplifying
the production control procedure, and for consumers of fi nished products. Confi rmed
compliance with the quality of goods allows, due to a unique selling proposition, to signifi cantly
expand the consumer audience, as well as increase sales volumes of products. The described
advantages of certifi cation of products that do not contain carcinogens increase the investment
attractiveness of the enterprise both from private investors and from funds of various types. The
article provides the main definitions of the certification process, a diagram of the organizational
structure during certification, requirements for raw materials and processes of production
(manufacturing), storage, transportation of products that do not contain carcinogens.
Information security at industrial enterprises and in budgetary organizations
Authors:   NPO LABS, Senik A.Y. , Kocherzhenko N.N. ,   OOO Advilabs-Rus
Published: February 2025

For industrial enterprises and budgetary organizations, the security of their IT
infrastructure and the smooth operation of automated processes are extremely important.
Since 2022, signifi cant changes have occurred in our country: Western vendors have left
Russia - companies that were engaged in the development and supply of information security
(IS) products. But the market quickly adapted to the new reality - and presented many of its
own tools in the field of IS.
Population and genetics research of cattle Simmental and Holstein red-and-white breeds by the alpha-lactalbumin (LALBA) gene in milk
Authors:   Federal State Budgetary Educational Institution of Higher Education “Voronezh State Agrarian University named after Emperor Peter I”, Russia, Voronezh, Fedorova M. I. , Larina O. V. ,   Federal State Budgetary Educational Institution of Higher Education “Voronezh State Agrarian University named after Emperor Peter I”, Russia, Voronezh, Voevodin A. V. ,   CenterPlem LLC, Russia, Moscow
Published: February 2025

Achievements of modern molecular genetics allow us to study genes associated with economically
useful traits of farm animals. The advantage of genomic selection in combination with classical
methods is the ability to predict the breeding value of an animal at an early age, almost immediately after
birth with an accuracy of up to 90 %. There are a number of genes that directly determine the productive
traits of dairy cattle. These include genes encoding milk proteins, including alpha-lactalbumin (LALBA)
which is an important protein in the whey of cow’s milk, as well as the milk of other mammals, encoded in
the human genome by the LALBA gene. The purpose of the research was to study the use of DNA markers
for the alpha-lactalbumin gene for the identifi cation, conservation and development of genetic resources
of Simmental and Red-and-White Holstein breeds. The study was carried out at JSC Breeding Enterprise
Voronezhskoye on three diff erent breeding and genetic groups of cows of Simmental breed and a group of
Holstein Red-and-White breed of animals. Analyzing the obtained data, it is necessary to note the highest
frequency of occurrence of the allele A of the LALBA gene in cows of Simmental breed of the improved
type (87.5 %). The lowest frequency of occurrence of the allele A was characterized by purebred cows of
Austrian selection (72.6 %). Analysis of the frequencies of occurrence of genotypes for the LALBA gene
showed that the highest frequency of occurrence of the AA genotype was revealed in the group of cattle
of Simmental breed of the improved type (85.0 %), and the lowest in cows of Simmental breed of the
Austrian selection (52.2 %). It should be noted that between the groups of purebred cows of Simmental
breed of Austrian selection, domestic selection and animals of the improved type of Simmental breed, no
reliable diff erence in the frequencies of occurrence of the allele A and the homozygous genotype AA was
observed, with the exception of differences in the frequency of occurrence of the AA genotype in animals of domestic selection and the improved type. It was established that purebred cows of Simmental breed of domestic selection did not have the BB genotype.
Improvement of the nutrient medium when rearing the larvae of the beetle Zophobas morio as a feed protein
Authors:   Federal State Budgetary Educational Institution of Higher Education “Lugansk State Agrarian University named after K. E. Voroshilov”, Russia, Lugansk People Republic, Lugansk, Medvedev A. Yu. , Figurak S. N. ,   Federal State Budgetary Educational Institution of Higher Education “Lugansk State Agrarian University named after K. E. Voroshilov”, Russia, Lugansk People Republic, Lugansk, Smetankina V. G. ,   Federal State Budgetary Educational Institution of Higher Education “Lugansk State Agrarian University named after K. E. Voroshilov”, Russia, Lugansk People Republic, Lugansk
Published: February 2025

The purpose of the research was to improve the nutrient medium for rearing Zophobas morio
beetle larvae as feed protein. When rearing Zophobas morio beetle larvae for the production of feed protein, it is effective to introduce the plant-based protein concentrate Solodo Pro into the traditional nutrient medium (bran, oats, vegetables) in the amount of 25 % of the total mass. This allows increasing their growth rate by 46–47 %, and the feed biomass accumulation rate by 1.7 times compared to the
traditional method of rearing larvae of this species while increasing the survival rate of larvae from 80
to 90 %. The use of Solodo Pro in the larval nutrient medium together with the concentrated solution of
vitamins and microelements Belavit FORTE contributes to the maximum increase in their protein content
from 17.2 to 19.5 % (by 22.7 g/kg or 13.2 % at p < 0.05) with similar lysine content in natural biomass
(0.41–0.47 % – 6.5–7.6 g/kg). In this case, the accumulation of insect feed protein increases by 2.4 times,
the lysine content in it by 1.8 times, and methionine+cystine by 2.0 times. The addition of Belavit FORTE
solution to the larval nutrient medium containing 25 % Solodo Pro does not lead to a signifi cant accumulation
of biologically active substances in their body. This approach allows increasing only the content of
vitamin E in Zophobas morio larvae from 10.5 to 41.6 mg/kg. At the same time, the content of vitamins
(D, B1 and B2) and microelements (Cu, Zn and Mn) in the biomass of larvae does not increase.
Cultivation of spring wheat and spring barley varieties under conditions of the Middle Urals
Authors:   Federal State Budgetary Educational Institution of Higher Education “Udmurt State Agrarian University”, Russia, Udmurt Republic, Izhevsk, Islamova Ch. M. , Borisov B. B. ,   Federal State Budgetary Educational Institution of Higher Education “Udmurt State Agrarian University”, Russia, Udmurt Republic, Izhevsk
Published: February 2025

The main reserve for obtaining high grain yield is the most complete realization of the productivity
potential of cultivated varieties. Only by introducing a new variety can the yield be increased by
50–70 %. The objective of the research was to identify spring wheat and spring barley varieties with high
adaptive properties of diff erent ecological and geographical origin for the conditions of the Middle Urals.
The object of the research was varieties of spring wheat and spring barley. The location of the fi eld research
was the Michurin collective farm in the Vavozhsky District of the Udmurt Republic. The correlation
coeffi cients and regression equations were calculated between the yield of spring wheat of Iren variety
and barley of Raushan variety with agrochemical parameters of the arable layer of sod-podzolic light
loamy soil, with meteorological conditions for the periods of plant development. The content of amino
acids and microelements in grain was determined. Regression equations were calculated between the yield and the concentration of microelements in the soil-plant chain. Thus, for the conditions of the
Middle Urals the research has identifi ed the spring wheat varieties Iren and Yoldyz, as well as the barley varieties Raushan and Belgorodsky 100 with a productivity of more than 4 t/ha, which was twice as high as the regional average. The highest net income and profi tability were demonstrated by the spring wheat varieties Iren (28,691 rubles/ha, 141 %, respectively), Yoldyz (28,495 rubles/ha, 140 %), barley varieties
Raushan (24,981 rubles/ha, 143 %) and Belgorodsky 100 (23,428 rubles/ha, 134 %). These varieties are
characterized by relatively high adaptability rates, which can serve as a recommendation for their cultivation under the conditions of the Middle Urals.
Organizing the feeding of highly productive cows in the most critical periods of their life
Authors:   Federal State Budgetary Educational Institution of Higher Education “Voronezh State Agrarian University named after Emperor Peter I”, Russia, Voronezh, Yesaulova L. A. , Kudinova N. A. ,   Federal State Budgetary Educational Institution of Higher Education “Voronezh State Agrarian University named after Emperor Peter I”, Russia, Voronezh
Published: February 2025

The objective of the work was to consider the optimal organization of feeding highly productive
cows during the most critical periods of their life. The need to reduce the cation and anion balance
of rations is dictated by the prevention of parturient paresis. The use of calcium propionate promotes
antimicrobial activity, reduces the content of mycotoxins in feed, and is a source of calcium and energy, which are so necessary in the post-calving period. In order to prevent the displacement of the abomasum,it is necessary to control the structure of the feed, which is carried out using the Pennsylvania sorting system. Sufficient feed structure will provide rumen filling of 3 points. Correct grinding of the feed mixture promotes optimal results of dry matter palatability, while feed losses are reduced by 4 %. Ketosis of
dairy cows is a disease of polyetiological nature. The measures for organizing feeding aimed at preventing ketosis include such as high quality of the main prepared feeds; feeding rations in the form of a mono
mixture; feeding corn grain; use of buff er additives; prevention of “milking down” of the body; control over the BCS fatness index; optimization of the level of crude protein in the rations of high-yielding cows. As an alternative to concentrates used as a source of energy in the rations of dairy cows, the farm feeds fractionated palm fats. Despite the higher cost of rations with fats, savings in feed costs for the production of 1 kg of milk were observed due to an increase in daily milk yield in cows received fat in the ration (36 kg), compared to cows without the use in their ration of palm fats (33 kg).
Influence of amaranth presscake on reproductive traits of sows
Authors:   Federal State Budgetary Educational Institution of Higher Education “Volgograd State Agrarian University”, Russia, Volgograd, Kutuzova A. V. , Karapetyan A. K. ,   Federal State Budgetary Educational Institution of Higher Education “Volgograd State Agrarian University”, Russia, Volgograd, Nikolaev S. I. ,   Federal State Budgetary Educational Institution of Higher Education “Volgograd State Agrarian University”, Russia, Volgograd, Chekhranova S. V. ,   Federal State Budgetary Educational Institution of Higher Education “Volgograd State Agrarian University”, Russia, Volgograd, Danilenko I. Yu. ,   Federal State Budgetary Educational Institution of Higher Education “Volgograd State Agrarian University”, Russia, Volgograd, Shkalenko V. V. ,   Federal State Budgetary Educational Institution of Higher Education “Volgograd State Agrarian University”, Russia, Volgograd, Morozova Е. A. ,   Federal State Budgetary Educational Institution of Higher Education “Volgograd State Agrarian University”, Russia, Volgograd
Published: February 2025

In feeding of farm animals, it is promising to search for new alternative feed sources and
additives. Some of these non-traditional feed sources are products of processing into oil such as mustard seeds, pumpkin, rapeseed, amaranth, etc. In this regard, ours investigations are aimed at assessing the effectiveness of using amaranth presscake in feeding of sows. The purpose of the work was to study the
infl uence of amaranth presscake on the reproductive traits of sows. Scientifi c research was carried out at the livestock enterprise TopAgro LLC in the Gorodishchensky district of the Volgograd region. During the scientific and economic experiment on sows four groups were formed according to the principle of analogues per 24 heads in each. The animals were housed indoor regime in special pens. The conditions
of housing animals for all experimental groups were identical and corresponded to zoo and hygienic standards.
The difference was in the pigs’ diets. Thus, the control group of pregnant sows received the main
diet with 10 % sunflower presscake, and lactating sows with 8 %. In the compound feed for the 1st experimental group of pigs 50 % of sunfl ower presscake was replaced with amaranth presscake, for the 2nd experimental
group this replacement was 75 %, and for the 3rd group sunfl ower presscake was completely
replaced with amaranth presscake. The research found that the main reproductive characteristics of sows,
such as the number of live piglets at delivery, heavy farrowing, milking capacity, litter weight at weaning, in animals of the 1st, 2nd and 3rd experimental groups were higher than in their herdmates from the
control group by 2.55–7.50 %, 0.81–5.65, 4.30–10.72 and 4.11–10.72 %, respectively. Thus, to improve
the reproductive traits of sows, we recommend input amaranth presscake into the compound feed recipe
instead of sunfl ower presscake in an amount of 4 to 10 % of the compound feed weight.
REFLECTION ON THE ESSENCE OF CREATIVITY IN PHILOSOPHICAL- ANTHROPOLOGICAL DISCOURSE
Authors: Kyvliuk Olga , Zadorozhna Olha
Published: February 2025

The research objective. Examining creativity through the lens of philosophical and anthropological discourse reveals its potential to generate new ideas that address issues such as freedom, responsibility, self-realisation, self-identity, and the creative quest. These aspects significantly influence an individual's sense of place in the world.
The statement of basic materials. The article examines the potential of human thought, particularly its capacity to generate new ideas and infuse them with theoretical depth, practical significance, and value orientations. By exploring the philosophical and anthropological aspects of creativity, it highlights its existential roots. This understanding enables individuals not only to adapt to their environment but also to actively transform it, thereby creating new elements of culture, knowledge, and social relationships.
Comorbidity of Wilson’s Disease and Alkaptonuria in a 12-Year-Old Child: A Case Report
Authors: Talakesh Hassan , Kasiri Karamali
Published: February 2025

Background: Wilson’s disease (WD) and alkaptonuria (AKU) are genetic diseases. Case Report: A 12-year-old boy presented with tremors, dysarthric drooling, poor school performance, and dark urine. Neurologic examination showed ataxia and Kayser-Fleischer (KF) rings in the eye examination. Black pigment deposits were observed in the subconjunctival area and on the sclera. Brain magnetic resonance imaging (MRI) indicated high signal intensity in the basal ganglia and head of the caudate nucleus of both sides in T2WI serum ceruloplasmin. Pathogenic homozygous variants were reported in whole exome sequencing for WD and AKU. Discussion: There is diagnostic complexity of overlapping metabolic disorders, including WD and AKU, in a pediatric patient with neurological and systemic symptoms. Genetic testing and biochemical analyses played a critical role in identifying pathogenic abnormalities. Conclusion: Rare genetic diseases such as WD and AKU can happen simultaneously
ON THE FIRST ATTEMPT TO COMMEMORATE THE SCIENTIFIC AND RESEARCH ACHIEVEMENTS OF THE
STATE JOURNALISM INSTITUTE AS A CENTER OF NEWSPAPER STUDIES
Authors: Fateeva I. A.
Published: February 2025

In the article, the author describes, analyzes and interprets documents related to
the earliest attempt at professional and academic commemoration of the scientific
research practices of newspaper scientists at the State Journalism Institute (SJI). This
is primarily the correspondence (1964–1967, Russian State Archive of Literature and Art)
of two active participants in the life of the first domestic educational institution for
journalists of the 1920s: Tomsk journalist V. A. Kuzmichev (1903–1994), graduate of the
post-graduate school of SJI, and his former supervisor M.S. Gus (1900–1984). On the
basis of commenting on the correspondents’ personal letters introduced into scientific
circulation, the author shows how toxic the topic of the formation and existence of the
first scientific journalism school was, even three and a half decades after its
liquidation.
Perspectives of education in the field of health security– reflections in the light of the results of own research
Authors: Sadłowska-Wrzesińska Joanna , Fiderer-Urbaniak Magdalena
Published: February 2025

A school that responds to the challenges of the future, cares for the safety of students, and ensurespsychosocial well-being are the requirements for modern education. The Ministry of National Educationassumes that the main area of educational policy in 2025 will be activities in the field of health education ofstudents, and in particular care for their physical and mental health. The aim of the article is to draw attention to the challenges for education in the field of health safety, and especially health education. The authors assumed that health education is an important element in the process of ensuring the desired level of health safety. Health safety includes both the prevention of health threats, as well as their control and ensuring lasting health support for society. Assuming that the key goal of these activities is to protect people's health and life, the process of shaping health safety cannot be devoid of educational activities. The publication presents selected results of research conducted among students of purposefully selected fields of study. The study used the diagnosticsurvey method, and the aim of the research was to identify students' opinions on various aspects of safety, with particular emphasis on health security. The study was conducted in the context of a health crisis (COVID-19 pandemic), which further highlighted the essence of the issues addressed. The results showed that students are aware of the changes and consequences brought about by the global health crisis. At the same time, students’ interest in introducing a subject in the field of health security to the study program should be described as only moderate, even though they appreciate the essence of this area of education and connect it with the concept of sustainable development.
Formalne przesłanki stosowania środków przymusu bezpośredniego wobec osób nieletnich
Authors: Świerczewski Łukasz
Published: February 2025

Zwiększająca się z roku na rok liczba czynów karalnych popełnianych przez osoby nieletnie, w szczególności przeciwko życiu i zdrowiu, powoduje coraz większy niepokój społeczny oraz wpływa negatywnie zarówno na poczucie bezpieczeństwa, jak i jego obiektywny stan. Organy ścigania oraz wymiar sprawiedliwości stwierdzają nasilenie agresywności, bezwzględności, brutalizacji oraz przestępstw dokonywanych w zorganizowanych grupach przestępczych. Funkcjonariusze służb o charakterze policyjnym sygnalizują zwiększającą się liczbę przypadków niestosowania się przez nieletnich do wydawanych poleceń i zachowania zgodnego z prawem w trakcie interwencji, co sprawia, że następuje konieczność użycia wobec nich środków przymusu bezpośredniego. Zastosowanie środków przymusu bezpośredniego wobec nieletnich wymaga spełnienia określonych przesłanek formalnych, w tym m.in. stwierdzenia bezpośredniego zagrożenia życia lub zdrowia funkcjonariuszy, osób postronnych bądź samego nieletniego, a także braku skuteczności innych, mniej inwazyjnych środków perswazji. W przypadku stosowania tych środków wobec nieletnich kluczowe jest również przestrzeganie zasady proporcjonalności, co oznacza, że użycie siły musi być adekwatne do poziomu zagrożenia i służyć ochronie porządku publicznego, a nie wyłącznie represji. Niniejszy artykuł poświęcony jest analizie obowiązujących przepisów normatywnych, regulujących kwestię stosowania przymusu bezpośredniego wobec członków społeczeństwa będących u progu dorosłości. Metodologia badawcza opiera się wyłącznie na analizie aktów prawnych, w szczególności ustaw i rozporządzeń określających zasady stosowania środków przymusu przez funkcjonariuszy służb państwowych. Celem analizy jest omówienie aktualnych regulacji oraz wskazanie ich potencjalnych konsekwencji dla praktyki stosowania środków przymusu wobec nieletnich.
CONGRESO INTERNACIONAL DE INVESTIGACIÓN EN EDUCACIÓN, EMPRESA Y SOCIEDAD – CIDIEES
Authors:   CONGRESO INTERNACIONAL DE INVESTIGACIÓN EN EDUCACIÓN, EMPRESA Y SOCIEDAD – CIDIEES
Published: February 2025

El Congreso Internacional de Investigación en Educación, Empresa y Sociedad – CIDIEES, es una estrategia de visibilidad creada por el Centro de Investigación Científica, Empresarial y Tecnológica de Colombia – CEINCET con el apoyo de la Red de Investigación en Educación, Empresa y Sociedad – REDIEES.

CIDIEES se convierte en un espacio donde los profesionales, especialistas, investigadores y académicos comparten su visión y discuten sobre los desafíos actuales, estudios de casos, soluciones prácticas e integradas, así como nuevos productos, hallazgos y enfoques entorno a la educación, la empresa y la sociedad.

Los académicos e investigadores tendrán la oportunidad de aportar nuevas ideas, debatir problemas e introducir los últimos desarrollos en el campo inter y transdisciplinario.
EL LENGUAJE DE LAS REDES: TEJIDO SOCIAL DE SABERES EN EL TRABAJO PSICOSOCIAL CON FAMILIAS
Authors:   Escuela Internacional de Negocios y Desarrollo Empresarial de Colombia
Published: February 2025

En la actualidad diversos profesionales de las ciencias humanas y sociales, nos cuestionamos sobre las particularidades del tejido social que cotidianamente advertimos en los diferentes espacios en los que nos encontramos. Observamos fenómenos tales como la violencia hacia la mujer, discursos de odio, discriminación y apoyo en las redes sociales, segregación a personas desplazadas por el hambre en Venezuela y de qué manera demandas que requieren atención psicosocial son desatendidas.
Aplikasi Media Pembelajaran Sinau Basa Berbasis Android pada Mata Pelajaran Bahasa Jawa Kelas V
Authors: Dodi Ghani Setiawan  , Sigit Sugiyanto  , Tito Pinandita  , Hindayati Mustafidah
Published: February 2025

The alpha generation is the generation born in 2010 to 2025. The birth and growth of the alpha generation is surrounded by technology which results in dependence on smartphones. The development of technology also has its urgency in the field of education. The independent curriculum emphasizes teachers to be able to integrate technology with learning media in the process of teaching and learning activities. However, the problems that occur in schools, there are still teachers who have not utilized technology in the learning process, especially in Javanese language subjects. Teachers still use conventional methods and rely on textbooks which results in the lack of enthusiasm of students during the learning process. Therefore, an android-based learning media application was developed with the aim of becoming a creative and innovative teacher's teaching media in delivering subject matter, supporting the independent learning process of fifth grade students of SD Negeri 2 Rajawana, and as a means of discussion between teachers and students. The system developer method used in developing this application is the Multimedia De-velopment Life Cycle (MDLC) which consists of 6 stages (Concept, Design, Material Collection, Manufacture, Testing, and Distribution). Based on black box testing, the Sinau Basa Learning Media Application can run smoothly according to its function on an Android Smartphone. Then, the N-Gain test results show a score of 64%. When referring to the value of g->56-75, it is included in the moderately effective category.
Etude critique de traduction Français – Anglais du Texte sur Agriculture: Problèmes Sémantiques
Authors: Iwala Gold , Ashiru-Abdulrahman Khadijah
Published: February 2025

La traduction c’est un passage d’une langue à une autre, c’est un outil indispensable pour le développement des nations. Nous disons sans ambages que l’importance de la traduction est vaste et multidimensionnelle. Ce travail concerne la traduction des textes de projet de développement agricole. Il s’agit d’un travail qui se circonscrit dans les domaines de la traduction des textes spécialisé c’est-à-dire un texte en agriculture, c’est un texte à caractère pratique et sensible à la réalité. C’est en ce sens que la traduction doit être bien faite. Nous utilisons la méthode d’analyse textuelle pour faire ce travail. On se donne pour tâche un examen des traductions déjà proposées dans ce domaine avec pour but de relever les points forts et les points faibles d’une telle traduction. Nous suggérons des remèdes pour minimiser certaines lacunes qui peuvent exister dans cette traduction.
MANAGEMENT STRATEGY DESIGN WITH SWOT ANALYSIS TO ENHANCE THE COMPETITIVENESS OF ROBBY BARBERSHOP IN PEKANBARU CITY
Authors: Ramdani Devinda , Suci Rama Gita , Ameliya Ameliya Gita , Murtaib Agum Gita
Published: February 2025

This study aims to provide and improve the competitiveness of Robby Barbershop Pekanbaru, which has been established for seven years, again facing tight competition that continues to change. Using SWOT analysis (Strengths, Weaknesses, Opportunities, Threats), the research method used is descriptive with a qualitative approach. Data were collected through semi-structured interviews with the use of interview guidelines as the main tool for collecting information. The resulting strategies include four approaches (1) S-O Strategy (maximizing strengths to take advantage of opportunities), (2) W-O Strategy (improving weaknesses by using opportunities), (3) S-T Strategy (utilizing strengths to face threats) and (4) W-T Strategy (reducing weaknesses and avoiding threats). This study provides insight into the importance of adapting management strategies for MSMEs in facing the dynamics of business competition. In a situation in order to continue to advance and develop, they need an effective marketing strategy
Perspectivas Inovadoras para a Correção Cirúrgica da Eritroblastose Fetal: Integração de Técnicas Modernas no Manejo Perinatal
Authors: Fechine Honorato Pedro , Moreira Graziella Ferreira , Arruda de Almeida Vitória , Guimarães Laura Vanalli , Severiano da Silva Jeferson , Almeida Raiany Brenda de Sousa , Silva Beatriz Zani , Neves Rafael Vieira , Barros Jorleane Pereira Silva , Magalhães Bárbara Bernardes
Published: February 2025

A eritroblastose fetal, ou doença hemolítica perinatal, é uma condição obstétrica grave resultante da incompatibilidade sanguínea materno-fetal, levando à produção de anticorpos maternos que atacam os eritrócitos fetais. Este estudo explora as perspectivas inovadoras para a correção cirúrgica dessa condição, enfatizando a integração de técnicas modernas no manejo perinatal. A metodologia incluiu uma revisão integrativa da literatura, analisando estudos publicados entre 2020 e 2025, guiada pela pergunta norteadora: "Quais são as abordagens mais inovadoras para o manejo cirúrgico da eritroblastose fetal e como elas podem impactar os desfechos perinatais?". Por fim, 15 artigos foram utilizados. Os resultados destacam avanços significativos em diagnósticos precoces e intervenções terapêuticas, como transfusões intrauterinas e terapia gênica. A discussão aborda os desafios e benefícios dessas abordagens, culminando na conclusão de que a incorporação de técnicas modernas é essencial para melhorar os desfechos perinatais em casos de eritroblastose fetal.
Atualizações no manejo da vertigem e doença de ménière: uma revisão integrativa
Authors: Ribeiro Sachi Julia , Borges Lopes Cristiano , Evelyn Nunes Turbano Myrella , Elen Araújo Silva Sarah , Gonçalves de Marins Lucas , Viscainho Francisco Eduardo , Barroso Maia Araujo Isabella , Garcia Scripiliti Isabella , Curtolo Carolina , Gabriela de Oliveira Manganeli Ana , Christina Araripe de Moraes Souza Oliveira Ana , Teixeira Verri Iago , Caroline Oliveira Marinho Luana , Treter Junior Nilton , Jorge Pinheiro de Araújo Pedro
Published: February 2025

Introdução: A vertigem, um sintoma incapacitante, pode estar associada à doença de Ménière, um distúrbio do ouvido interno caracterizado por crises recorrentes de vertigem, zumbido, perda auditiva e plenitude auricular. O diagnóstico é desafiador devido à sobreposição de sintomas com outras doenças vestibulares, exigindo exames complementares e critérios clínicos específicos. Nos últimos anos, avanços diagnósticos e terapêuticos têm sido desenvolvidos para melhorar o manejo da condição. Metodologia: Trata-se de uma revisão integrativa da literatura baseada na estratégia PICo, com busca realizada nas bases LILACS, SciELO, PubMed e Scopus. Foram selecionados artigos publicados entre 2020 e 2025 que abordassem novas abordagens diagnósticas e terapêuticas para a doença de Ménière. Após a triagem, 12 estudos foram incluídos na análise. Resultados e Discussão: Os avanços incluem o uso de exames como a videoeletronistagmografia e a ressonância magnética de alta resolução para um diagnóstico mais preciso. No tratamento, destacam-se o uso de betahistina, corticosteroides intratimpânicos e a reabilitação vestibular. Abordagens minimamente invasivas, como a gentamicina intratimpânica e a neurotomia vestibular, mostraram eficácia em casos refratários. A adoção de estratégias multidisciplinares e mudanças no estilo de vida também demonstraram benefícios na qualidade de vida dos pacientes. Conclusão: Os avanços no manejo da vertigem e da doença de Ménière têm aprimorado o diagnóstico e o tratamento, proporcionando maior controle dos sintomas e melhor prognóstico. A continuidade das pesquisas é essencial para otimizar as intervenções terapêuticas e garantir assistência baseada em evidências.