bluuebunny/crossref_metadata_2025 huggingface dataset:
Synthesis of Substituted Heterocyclic Ureas by Selenium-Catalysed Carbonylation using Carbon Monoxide
Authors: Ling Gang , Chen Jingzhu , Lu Shiwei
Published: December 2009

A series of commercially useful substituted heterocyclic ureas have been synthesised via selenium-catalysed reductive carbonylation of substituted nitrobenzezes with aminopyridine or aminopyrimidine derivatives as co-reagents and carbon monoxide as carbonylating reagent.
The Investigation of a Novel Conversion of Hydroxybenzaldehydes and Acetophenones into hYdroquinone Monoalkyl Ethers
Authors: Barton Benita , Hoffmann Petra F. , Zeelie Bernard
Published: December 2009

The scope and mechanism of a novel conversion reaction of hydroxyacetophenones and hydroxybenzaldehydes into hydroquinone monoalkyl ethers when reacted with an oxidant and an alcohol in the presence of a strong acid catalyst are reported here.
Fused Quinoline Heterocycles V. Synthesis of Novel 1,2,3,5,6-Pentaazaaceanthrylene Derivatives
Authors: Mekheimer Ramadan Ahmed , Ahmed Essam Khalaf , El-Fahhama Hassan Attia , Kamel Laila Hanafy , Döpp Dietrich
Published: December 2009

2,4-Dichloroquinoline-3-carbonitrile (1) with phenylhydrazine in DMF at room temperature gave the 3-amino-4-chloro-1-phenylpyrazolo[4,3- c]quinoline (2). Reaction of 2 with phenyl isothiocyanate afforded the novel fused tetracyclic ring system 1,5-diphenyl-1,5-dihydro-1,2,3,5,6-pentaazaaceanthrylene-4(3 H)-thione (7). Refluxing 2 with excess of a primary amines 8a-d in boiling DMF yielded the corresponding aminopyrazolo[4,3- c]quinolines 9a-d which react with an excess of triethyl orthoformate to furnish 5-substituted 1-phenyl-1,2,3,5,6-pentaaza-aceanthrylenes 11a-d. Reacting 9a with acetic anhydride does not give the expected tetracyclic compound 12, but instead the acetamide 13 is obtained. With triethyl orthoacetate the corresponding iminoester 14 is formed. When compound 14 was refluxed in DMF containing NaH it cyclised to the 4-methyl analogue 12.
Solubility of 2-Naphthol in Organic Nonelectrolyte Solvents. Comparison of Observed Versus Predicted Values Based Upon Mobile Order and Regular Solution Theories
Authors: Azizian Saeid , Pour Afshin Haydar
Published: December 2009

Experimental solubilities are reported at 25.0°C for 2-naphthol in several different organic nonelectrolyte solvents; results of these measurements are compared with the solubility equations derived from mobile order and regular solution theories.
Kinetics and Mechanism of Oxidative Decarboxylation of Benzilic Acid by Alkaline Permanganate Using the Stopped-Flow Technique
Authors: Farokhi Sairabanu A. , Nandibewoor Sharanappa T.
Published: December 2009

A mechanism involving the formation of complex between benzilic acid and permanganate has been proposed for the title reaction and activation parameters for the slow step of reaction and reaction constants involved in the mechanism were calculated and discussed.
Highly Regioselective Nucleophilic Addition of the Allylsamarium Bromide to α, β-Unsaturated Alkynones
Authors: Zheng Xingliang , Zhang Yongmin
Published: December 2009

Allylsamarium bromide reacts with α, β-unsaturated alkynones to afford reginospecific nucleophilic addition products in good yields under mild conditions.
Oxidative Conversion of Aldoximes into Carboxylic Acid Esters Catalysed by Polystyrene-Bound Phenylseleninic Acid
Authors: Sheng Shou-Ri , Huang Xian
Published: December 2009

Aromatic and aliphatic aldoximes were catalytically oxidised to carboxylic acid esters in good to moderate yields with hydrogen peroxide as oxidant using polystyrene-bound phenylseleninic acid as catalyst.
Formation of a Turn like Structure in BocNH(CH2)2CON(C6H11)CONH(C6H11): An X-Ray Diffraction Study
Authors: Mazumdar Pooja Anjali , Kundu Sandip Kumar , Das Amit Kumar , Bertolasi Valerio , Pramanik Animesh
Published: December 2009

β-Alanine is an amino acid which is important in the design of diverse peptides. Crystallographic study shows that the N-acyl adduct of β-Alanine, an ω-amino acid important in peptide design for the production of structural and functional diversities, and N,N′-dicyclohexyl urea(DCU) forms a turn like structure without any intra-molecular hydrogen bonding.
Synthesis of (+)-Coronarin E, (-)-7-epi-Coronarin a and (+)-15, 16-Epoxy-8(17), 13(16), 14-Labdatriene from (+)-Manool
Authors: Villamizar José , Salazar Franklin , Fuentes Juan , Tropper Eleonora , Alonso Randolph
Published: December 2009

An efficient method for the synthesis of (+)-coronarin E 1, (+)- epi-coronarin A 2 and (+)-15, 16-epoxy-8(17), 13(16), 14-labdatriene 3 via the homodrimane 9, obtained in four steps from (+)-manool 5, is described.
Fused Heterocycles. Part I. Synthesis of Some Annelated 1,2,4-Triazole Systems from [4-(1H-Benzimidazol-2-yl)-Phthalazin-1-Yl]Hydrazine
Authors: Wasfy A.A.F.
Published: December 2009

Substituted 6-(1 H-benzimidazol-2-yl)-[1,2,4]triazolo[3,4- a]phthalazine derivatives containing alkyl, aryl, hydroxyl, mercapto, methylthio and formyl substituents at position 3 have been synthesised. Di-[6-(1 H-benzimidazol-2-yl)-3-[1,2,4]triazolo[3,4- a]phthalazin-3-yl]alkanes have been obtained by the use of dicarboxylic acids or their esters in the above condensations. Methylation reactions of the triazolo-phthalazine system are reported.
Mild and Convenient Method for Reduction of Aliphatic and Aromatic Carboxylic Acids and Anhydrides with (Pyridine)(Tetrahydroborato)Zinc Complex as a New Stable Ligand-Metal Tetrahydroborate Agent
Authors: Zeynizadeh Behzad , Zahmatkesh Karam
Published: December 2009

Structurally different aliphatic and aromatic carboxylic acids and anhydrides are efficiently reduced to their corresponding alcohols with a new modified zinc tetrahydroborate agent, (pyridine)(tetrahydroborato)zinc complex, [(Py)Zn(BH4)2], in refluxing THF.
Syntheses and Characterisation of Amide Adducts of Uranyl Bis (β-Diketonates) the Molecular Structure of [UO2(DBM)2.C4H9CON(3-C5H11) (sec-C4H9)]
Authors: Rajagopal K. , Kannan S. , Venugopal V. , Krishnakumar R.V. , Nandhini M. Subha , Natarajan S.
Published: December 2009

The first structurally characterised uranyl bis (β-diketonate)-amide adduct compound [UO2(DBM)2. C4H9CON ( 3-C5H11) ( sec-C4H9)] (DBM = dibenzoylmethanate) shows that the amide ligand bonded through its amido oxygen atom to the uranyl group. The average bond distances for U–O(uranyl), U–O(DBM) and U–O(amide) are 1.778(5), 2.346(5) and 2.411(5)Å respectively.
A New Route to Non-Natural Aryl-Containing Amino Acids and Their Precursors from Thiophenes
Authors: Dongol Krishna Gopal , Mataka Shuntaro , Thiemann Thies
Published: December 2009

Thiophenes may be converted to substituted arenes by oxidative cycloaddition to alkynes or by oxidative cycloaddition to alkenes with subsequent oxidative SO-extrusion. Cyano- and acetylamino-groups do not interfere in the reaction and are stable under the reaction conditions. This transformation can be used as a novel route to non-natural aryl-containing amino acids.
New Modes of Coordination for the β-Disulfoxide Ligand. The Crystal and Molecular Structure of [{UO2(DBM)2}2PhSOCH2SOPh]
Authors: Rajalakshmi N. , Kannan S. , Venugopal V. , Usman A. , Fun H. K.
Published: December 2009

The X-ray structure of the compound [{UO2(DBM)2}2C6H5SOCH2SOC6H5] confirms the bridging bidentate mode of coordination for the β-disulfoxide ligand C6H5SOCH2SOC6H5.
One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones Using Cadmium Sulfate as Catalyst
Authors: Tu Shujang , Fang Fang , Miao Chunbao , Jiang Hong , Shi Daqing , Wang Xiangshan
Published: December 2009

A simple effective synthesis of 3,4-dihydropyrimidin-2(1 H)-one derivatives from aromatic aldehydes, 1,3-dicarbonyl compounds and urea in glacical acetic acid using cadmium sulfate as catalyst is described and compared with the classical Biginelli reaction conditions, this new method has the advantage of excellent yields (83–94%) and short reaction time (2-4 h).
Ab Initio Study of Conformational Properties of (Z,Z,Z)-Cyclonona-1,3,6-Triene
Authors: Nori-Shargh Davood , Amini Mostafa Mohammadpour , Jameh-Bozorghi Saeed , laalee Nooshin Heydari
Published: December 2009

Ab initio molecular orbital and density functional theory (DFT) calculations, applied to ( Z,Z,Z)-cyclonona-1,3,6-triene (1) have revealed that the calculated energy barrier for ring inversion of the twist-boat ( C1 symmetry) conformation of 1 as a most stable form is 8.41 kcal mol−1, as calculated by the MP2/6-31G*//HF/6-31G* method
The Conformation of the Side Chain of 21-Alkylpregnanes
Authors: Hanson James R. , Hitchcock Peter B. , Salvador Jorge A.R.
Published: December 2009

The X-ray crystal structures of some 21-alkylpregnanes have been determined and the effects of a 16α,17α-epoxide and 21-methyl group on the conformation of the side chain are discussed.
A Tandem Michael Addition–Rearrangement–Carbonylation by (4-Nitrophenylsulfonylmethyl) Benzene and Its Derivatives with Methacrylates under PTC
Authors: Yue Guoren , She Xuegong , Zhang Zheng , Pan Xinfu
Published: December 2009

A novel tandem Michael addition–rearrangement–carbonylation was studied in the reaction of (4-nitrophenylsulfonylmethyl)benzene(1) and its derivatives with methacrylates (2) under solid–liquid PTC conditions and a probable mechanism is discussed.
An Improved Procedure for the Isomerisation of 2′-Hydroxysubstituted Chalcones to Flavanones Using Silica Supported-BiCl3 Under Dry Conditions
Authors: Ahmed Naseem , Ansari W.H.
Published: December 2009

The isomerisation of 2′-hydroxychalcones to their corresponding flavanones, in good to excellent yield using silica supported-Bi(III) chloride as a catalyst under dry conditions at 70-80°C is reported.
Novel Dispiro Iminodioxolane Derivatives: Synthesis by Reaction of Isocyanides with Ninhydrin
Authors: Shaabani Ahmad , Teimouri Mohammad Bagher , Bijanzadeh Hamid Reza
Published: December 2009

The reaction of isocyanides 1 with two equivalent of ninhydrin 2 gives Cs symmetry dispiro iminodioxolanes 3 at refluxing conditions in chloroform in fairly high yields.
Theoretical Study on the Mechanism of Robinson's Synthesis of Tropinone
Authors: Mondal Nityagopal , Mandal Sannyasi Charan , Das Gourab Kanti , Mukherjee Sarbananda
Published: December 2009

Ab initio quantum mechanical calculation reveals that the first Mannich reaction in Robinson's tropinone synthesis involves both carbon–carbon bond formation and water elimination, which is followed by tautomerisation and a second Mannich reaction to form the protonated tropinone.
Mild and Regioselective Oxidative Bromination of Aromatic Compounds Using Ammonium Bromide and Oxone®
Authors: Narender N. , Mohan K.V.V. Krishna , Kulkarni S.J. , Raghavan K.V.
Published: December 2009

The selective mono-bromination of various activated aromatic compounds is reported using in situ generated bromine from NH4Br as a bromine source and oxone® as an oxidant for the first time.
Useful Synthesis of Aryl Cinnamates: Synthesis of Difengpin
Authors: Mali Raghao S. , Papalkar Abhijit S.
Published: December 2009

A convenient, high yield and general method is described for the synthesis of difengpin (8a) and aryl cinnamates (8b–h and 9a,b) from benzaldehydes (7a–h).
Organic Reactions in Ionic Liquids: Oxidative Dimerisation of Thioamides with Phenyliodine(III) Diacetate
Authors: Yan Mi , Chen Zhen-Chu , Zheng Qin-Guo
Published: December 2009

The room temperature ionic liquid, 1- n-butylpyridinium tetrafluoroborate (BPyBF4), is used as a “green” recyclable solvent for the oxidative dimerisation of thioamides with phenyliodine(III) diacetate which provides a facile, efficient and environmentally benign method for the synthesis of 3,5-diaryl-1,2,4-thiadiazoles.
Reactions of Bis(N-Phenylsalicylidene Iminato)Aluminium-Di-μ-Isopropoxo-Di-Isopropoxo Aluminium(III) with Glycols
Authors: Sharma Nikita , Sharma Rajnish K. , Bohra Rakesh
Published: December 2009

Reactions of bis(N-phenylsalicylidene iminato)aluminium-di-μ-isopropoxo-di-isopropoxo aluminium(III), [C6H4O{CH=N(C6H5)}]2Al(μ-OPri)2Al(OPri)2 with glycols in 1:1 molar ratio in refluxing anhydrous benzene yielded binuclear complexes of the type, [C6H4O{CH=N(C6H5)}]2Al(μ-OPri)2Al(O-G-O) [where G = (CH2)2, CH2CH(CH3), CH2CH(C2H5), CH(CH3)CH(CH3), (CH2)5, C(CH3)2CH2CH(CH3), (CH2)6], respectively. All these binuclear complexes have been characterised by elemental analysis, molecular weight measurements and spectroscopic(IR and NMR) studies.
A Simple and Efficient Method for the N-Nitrosation of Secondary Amines with NaNO2–Ac2O Under Mild Conditions
Authors: Hou Jian-Ye , Wang Yu-Lu , Wang Jin-Ye
Published: December 2009

Secondary amines can be easily converted into their corresponding nitroso derivations using NaNO2–Ac2O as a nitrosating agent in dichloromethane at room temperature with high yields.
A Convenient and Improved Montmorillonite K-10 Catalysed Friedel–Crafts Benzylation and Allylation with Activated Esters
Authors: Karade N.N. , Shirodkar S.G. , Potrekar R.A.
Published: December 2009

Benzyl benzoate and cinnamyl acetate has been effectively used respectively as alkylating and allylating substrates in Friedel–Crafts reaction catalysed by montmorillonite K-10 clay.
On the Stereochemistry of the Synthesis of 1-(2-Cyano-2-Methoxyiminoacetyl)-3-Ethylurea and Its E-Configuration Crystal Structure
Authors: Greci Lucedio , Carloni Patricia , Mandrioli Odofredo , Righi Lara , Rizzoli Corrado , Sgarabotto Paolo
Published: December 2009

The synthesis of 1-(2-cyano-2-methoxyiminoacetyl)-3-ethylurea leads to only one of the two possible diastereomers, which has been found to be in the E-configuration by X-ray analysis.
Zinc/Ammonium Formate: A Chemoselective and Cost-Effective Protocol for the Reduction of Azides to Amines
Authors: Srinivasa G.R. , Nalina L. , Abiraj K. , Gowda D. Channe
Published: December 2009

A variety of alkyl and aryl azides were selectively reduced in high yields to the corresponding amines by reaction with ammonium formate in the presence of low cost commercial zinc dust at room temperature.
Oxidation of Vicinal Diketones with Manganese(III) Fluoride
Authors: Duvaux Dorothée , Ho Jason , Hughes D.E. Peter
Published: December 2009

Vicinal diketones were oxidised, at room temperature, to carboxylic acids by manganese(III) fluoride with 90% yield. Investigation of the kinetics suggested that the reaction proceeded via a cyclic intermediate.
Three-Component Processes for the Synthesis of 4-Aryl-7,7-Dimethyl-5-Oxo-3,4,5,6,7,8-Hexahydrocoumarin in Aqueous Media
Authors: Shi Daqing , Chen Jing , Zhuang Qiya , Hu Hongwen
Published: December 2009

The reaction of an aromatic aldehyde, isopropylidene malonate and 5,5-dimethyl-1,3-cyclohexanedione in water in the presence of triethylbenzylammonium chloride (TEBA) as catalyst affords a one-pot synthesis of 4-aryl-7,7-dimethyl-5-oxo-3,4,5,6,7,8-hexahydrocoumarin.
Iridoid Glucosides from Chinese Herb Lonicera Chrysatha and Their Antitumor Activity
Authors: Wang Yuli , Wei Qingyi , Yang Li , Liu Zhong-Li
Published: December 2009

A new bis-iridoid glucosides, secologanin methyl hemiacetal-yl-6′-secologanin dimethyl acetal (chrysathain, 1), was isolated from the methanol extract of the leaves of Chinese medicinal plant Lonicera chrysatha along with nine known iridoid glucosides, i.e., loganin (2), secologanin (3), secologanin dimethylacetal (4), 8-epi-kingiside (5) 7α-morroniside (6), 7β-morroniside (7), vogeloside (8) 7-epi-vogeloside (9) and sarracenin (10). Their structures were elucidated by spectroscopic methods. Compounds 1–5 showed moderate in vitro antitumour activity against human promyelocytic leukemia (HL-60) cells.
Tris[(2-Oxazolinyl)Phenolato]manganese(III) as Catalyst for Mild and Efficient Oxidation of Sulfides to Sulfones with Oxone®
Authors: Bagherzadeh Mojtaba
Published: December 2009

Tris[(2-oxazolinyl)phenolato]manganese(III), Mn(phox)3, catalysed oxidation of dialkyl, diaryl, dibenzyl, and alkyl aryl sulfides to the corresponding sulfones is carried out by Oxone® in biphasic conditions (CH2Cl2/H2O), in the presence of tetra n-butylammonium bromide as phase transfer agent at room temperature in very short reaction times (5 min.) with quantitative yields.
Synthesis of Symmetric 1,3,5-Triarylbenzenes
Authors: Hu Zhi Guo , Liu Jun , Li Gong An , Dong Zhi Bing
Published: December 2009

A facile and efficient method for synthesis of symmetric 1,3,5-triarylbenzenes is presented; six symmetric 1,3, 5-triarylbenzenes was obtained from their corresponding substituted acetophenones in the presence of thionyl chloride in anhydrous ethanol.
Stereoselective Synthesis of 1,4-Dienylsilanes via Hydromagnesiation of Alkynylsilanes
Authors: Zhao Hong , Hao Wenyan , Cai Mingzhong , Zhou Zhou
Published: December 2009

Hydromagnesiation of alkynylsilanes 1 gave ( Z)-α-silylvinyl Grignard reagents 2, which underwent coupling reaction with allylic chlorides 3 to give stereoselectively 1,4-dienylsilanes 4 in good yields: the products 4 can undergo the desilylation reaction in the presence of a catalytic amount of hydriodic acid to afford stereoselectively 1,4-dienes 5 in high yields.
The Oxidation of 3-Hydroxy-3-Methyl-Δ4-Steroids by Chromium Trioxide
Authors: Uyanik Cavit , Hanson James R. , Hitchcock Peter B.
Published: December 2009

Oxidation of the allylic tertiary alcohols of 3-hydroxy-3-methyl-Δ4-steroids by chromium trioxide in sulfuric acid leads to C–C bond fission together with the formation of a 3-methylestra-1,3,5(10)-triene from a 19-nor steroid and a 3β,4β-epoxy-5β-hydroxy compound from an androstane; the structure of the hydroxy-epoxide was established by X-ray crystallography.
Gas-Phase Infrared Spectrum of Vanadium (III) Oxyfluoride, OVF: Theoretical and Experimental Investigations
Authors: Allaf Abdul W.
Published: December 2009

The gas phase infrared spectrum of vanadium (III) oxyfluoride, OVF has been recorded. The molecule was generated for the first time by an on-line process using vanadium oxychloride, OVCl, as a precursor passed over heated sodium fluoride at about 570°C. The infrared spectrum shows two bands centred at 1028, and 807 cm−1, which are assigned to ν3 (O=V stretch) and ν2 (V–F stretch), respectively. Ab initio self-consistent-field (SCF) molecular orbital (MO) calculations were performed to determine the geometry, total energy and the vibrational frequencies of OVF.
Dimer of Trifluoropyruvic Acid: Synthesis and Molecular Structure
Authors: Sevenard Dmitri V. , Loop Ildikó , Lork Enno , Breuer Eli , Röschenthaler Gerd-Volker
Published: December 2009

The dimer of trifluoropyruvic acid was obtained starting from perfluoropropene-1,2-oxide in good yield by a simple and convenient procedure, and its structure was confirmed by X-ray diffraction.
Synthesis and Crystal Structure of Dichloro{Bis [N-(4-Methyl-2-Pyridinyl)Acetamide]} Copper (II)
Authors: Zhang Wen , Leng Xuebing , Sun Wen-Hua
Published: December 2009

Dichlorobis[ N-(4-methyl-2-pyridinyl)acetamide] copper (II) was prepared and its structure was first resolved by X-ray analysis.
Organic Reactions in Ionic Liquids: Synthesis of Alkyl Aryl Trithiocarbonates by the S-Arylation of Potassium Carbonotrithioates with Diaryliodonium Salts
Authors: Wang Feng-Yan , Chen Zhen-Chu , Zheng Qin-Guo
Published: December 2009

Various alkyl aryl trithiocarbonates were readily prepared in good yields by the S-arylation of potassium carbonotrithioates with diaryliodonium salts in the room-temperature ionic liquid, 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim]BF4). The ionic liquid can be recycled and reused.
Synthesis of Phenols and Naphthols by Alkali Metal Hydroxide Fusion under Microwave Irradiation
Authors: Ghaffarzadeh Mohammad , Bolourtchian Mohammad , Halvagar Mohammad Reza , Hosseini Maryam
Published: December 2009

Sodium aryl sulfonates were efficiently converted into to phenols and naphthols under microwave irradiation.
High Yield Synthesis of Aryl Cyanides under Microwave Irradiation
Authors: Ghaffarzadeh Mohammad , Bolourtchian Mohammad , Halvagar Mohammad Reza , Hosseini Maryam
Published: December 2009

Reaction of anhydrous cuprous cyanide with aryl bromides produced aryl cyanides (Rosenmund–von Braun reaction) under microwave irradiation in a short time and in high yield.
Improvement of Selectivity in the Fries Rearrangement and Direct Acylation Reactions by Means of P2O5/SiO2 Under Microwave Irradiation in Solvent-Free Media
Authors: Eshghi Hossein , Rafie Mohammad , Gordi Zinat , Bohloli Moosa
Published: December 2009

P2O5 / SiO2 was found to be an efficient new reagent in the Fries rearrangement of acyloxy benzene or naphthalene derivatives and the direct acylation reactions of phenol and naphthol derivatives with carboxylic acids under microwave irradiation in solvent-free media.
Synthesis of New Halogenated Flavonoids by Reaction with Hydrogen Halides in the Presence of Dimethyldioxirane
Authors: Arnone Alberto , Nasini Gianluca , Panzeri Walter , De Pava Orso Vajna , Zucca Cristina
Published: December 2009

This paper presents the synthesis and characterisation of new halogenated etherderivatives of flavans, flavanols and flavanones, obtained by reaction of the corresponding methyl ethers with hydrogen halides in the presence of dimethyldioxirane as an oxidative agent.
Nitriles in Heterocyclic Synthesis: The Preparation of Novel Indeno[1,2-d]Pyridazines, Fused Pyrazolo [5,1-c][1,2,4]Triazines, and Fluorenones
Authors: Hassanien Abu Zeid A. , Kandeel Zaghloul E.
Published: December 2009

Treatment of the novel compound (2-cyano-1-oxo-1 H-indene-3-yl) acetonitrile (3) with various reagents affords a variety of heterocyclic compounds in which the indenone system is incorporated into polycyclic compounds of potential pharmacological interest.
Synthesis of Diarylmethylamines via Electrophilic Trapping of Tricarbonyl Chromium Complexed Aryllithium Intermediates with Imines
Authors: Chen Yong-Jun , Zhao Cui-Hua , Liu Li , Wang Dong
Published: December 2009

Diarylmethylamine derivatives 4a–l were synthesised in good yields via lithiation of the tricarbonyl (η6-arene) chromium complexes 1, followed by electrophilic trapping with imines 2 and decomplexation (sunlight and air).
Polyheterocyclic Systems Incorporating Pyrazole, Thiophene, Thiazole, and Thiadiazole Moieties
Authors: Dawood Kamal M. , Ragab Eman A. , Farag Ahmad M.
Published: December 2009

A variety of polyheterocyclic ring systems having pyrazole, thiophene, thiazole and thiadiazole moieties are synthesised utilising the reaction of sulfur functionalised substrates with α-halocarbonyl compounds and hydrazonyl chlorides.
A Facile Synthesis of Dihydronaphthopyrans
Authors: Ranade Anup A. , Joseph Augustine R. , Kumbhar Virendra B. , Paradkar Madhusudan V.
Published: December 2009

Efficient syntheses of the naturally occurring linear dihydronaphthopyran (6a) and its angular analogues (3b and 4), from the appropriate ortho-methoxynaphthaldehydes, are described.
Ytterbium(III) Trifluoromethanesulfonate Catalysed Friedel–Crafts Acylation of Substituted Thiophenes
Authors: Su Weike , Jin Can
Published: December 2009

Ytterbium(III) trifluoromethanesulfonate [Yb(OTf)3] has been used to catalyse Friedel–Crafts acylation of substituted thiophenes in different solvents to produce several intermediates of pharmaceuticals and pesticides with good yields. The amount of catalysis was discussed and Yb(OTf)3 could be reused without loss of activity.
Facile Preparation of 2,3-Disubstituted Indole Derivatives through Low-Valent Titanium Induced Intramolecular Reductive Coupling Reactions of Acylamido-Carbonyl Compounds
Authors: Fan Xuesen , Zhang Xinying
Published: December 2009

An efficient synthesis of 2,3-disubstituted indole derivatives through low-valent titanium induced reductive cyclisation of suitably substituted acylamido-carbonyl compounds is described.
Deacetylation of 2′-O-Ts-3′,5′-Di-O-Acetylpurine Nucleosides via a Free Radical Reaction
Authors: Liu Qi-Bin , Feng Feng , Qu Gui-Rong
Published: December 2009

A new method for deprotecting acetyl groups of blocked purine nucleosides has been established by using tri- n-butyltin hydride ( n-Bu3SnH) in the presence of α, α′-azobisisobutyronitrile (AIBN) without affecting OTs group.
Microwave-Assisted Rapid Synthesis of Furan Annulated Heterocycles
Authors: Shaabani Ahmad , Teimouri Mohammad Bagher
Published: December 2009

The one-pot three-component condensation reactions of 4-hydroxycoumarin or 4-hydroxy-6-methylpyrone 1, p-substituted benzaldehydes 2 and alkyl or aryl isocyanides 3 to afford furan annulated heterocycles, in high yields after 3 minutes under microwave irradiation, are reported.
A Rapid Solid-State Synthesis of Diazenecarboxamide-Azo Compounds Using Ferric Nitrate and Sodium Bisulfate as an Oxidation System
Authors: Xue Wan-Xin , Jian-Ping Li , Zhang Xin-Ying , Wang Yu-Lu
Published: December 2009

A new and rapid solid-state method for the preparation N-aryl-2-phenyl-diazenecarboxamide azo compounds from aryl substituted semicarbazides is reported. With this method, nine diazenecarboxamide compounds have been synthesised in good to excellent yields (89–98%). In addition, this method has the advantages of mild reaction conditions, cheap reagents, simple methodology and short reaction times.
Ion Exchange Resin Catalysed Reactions of Indole with Imines: Formation of Diindolylmethanes
Authors: Feng Xin-Liang , Guan Chuan-Jin , Zhao Cheng-Xue
Published: December 2009

Ion exchange resins are found to catalyze the reactions of indole with imines under mild conditions, affording diindolylmethanes in good yields.
A comparative study on the synthesis of 3′-aryl-3-methyl/2, 3-dimethylspiro[6,7,8,9-tetrahydro-5H-benzo[a]cyclohepten-5, 2′-(tetrahydro[1,3] thiazolane)]-4′-ones using microwave irradiation and conventional methods
Authors: Venkateswarlu Peesapati , Vasireddy Nageswara Rao
Published: December 2009

A convenient one pot synthesis of 3′-aryl-3-methyl/2,3-dimethylspiro[6,7,8,9-tetrahydro-5 H-benzo[a]cyclohepten-5,2′-(tetrahydro[1,3]thiazolane)-4′-ones under microwave irradiation, as well as conventional methods, is described. Microwave irradiation has resulted in the reduction of time from hours to minutes. Antimicrobial activity of these compounds was studied and that some compounds gave positive results.
Synthesis of 4-acetylaminobenzo[15]crown-5
Authors: Wei Tai-Bao , Zhou Yan-Qing , Zhang You-Ming
Published: December 2009

The synthesis of 4-acetylaminobenzo[15]crown-5 is reported by the reaction of benzo[15]crown-5, glacial acetic acid and hydroxylamine hydrochloride, where C-acylation, oximation, and Beckmann rearrangement are conducted in a one–pot reaction with polyphosphoric acid as catalyst.
Microwave promoted efficient synthesis of N–aryl–N′–ethoxycarbonyl thioureas under solvent-free and phase-transfer catalysis conditions
Authors: Lin Qi , Zhang You-Ming , Wei Tai-Bao , Wang Hai
Published: December 2009

A series of N–aryl– N′–ethoxycarbonyl thioureas 3a-j were synthesised under microwave irradiation, phase transfer catalysis and solvent-free conditions.
Decarboxylative photooxygenation of arylacetic acids by using mercuric oxide
Authors: Habibi Mohammad H. , Farhadi Saeid
Published: December 2009

A new method for decarboxylative photooxygenation of arylacetic acids is developed by using light sensitive HgO in MeCN-MeOH which leads to aldehydes and ketones in high yield through trapping of benzylic radical intermediates by dioxygen.
Highly selective iodination of phenols using potassium iodide and benzyltriphenylphosphonium peroxymonosulfate
Authors: Hajipour Abdol Reza , Adibi Hadi
Published: December 2009

An easy and selective method for monoiodination of phenols using potassium iodide in the presence of benzyltriphenylphosphonium peroxymonosulfate is presented. The reactions have been carried out in acetonitrile to afford the corresponding iodophenols in moderate to high yields.
A new diterpenoid alkaloid from a Tibetan medicinal herb Aconitum naviculare Stapf
Authors: Gao Liming , Wei Xiaomei , Yang Li
Published: December 2009

A new diterpenoid alkaloid, named as navirine (1), was isolated along with five known alkaloids, i.e., isoatisine (2), hordenine (3), atisine (4), hetisinone (5) and delfissinol (6), from the ethanol extract of the whole plant of Tibetan medicinal plant Aconitum naviculare Stapf. The structure of the new compound was established on the basis of HR-MS, 1H, 13C and 2D NMR spectroscopic methods.
Designer ligands. Part 12.1 Synthesis and evaluation of novel palladium(II)–selective ligand systems
Authors: Gxoyiya Babalwa S.B. , Hagemann Justin P. , Kaye Perry T.
Published: December 2009

Sulfur-containing, PGM-selective, diamide ligands, developed for solvent extraction applications or use in the construction of molecularly imprinted polymers (MIPs), have been shown to exhibit significant selectivity for palladium(II) over copper(II), nickel(II) and cobalt(II).
Synthesis and structural aspects of some intermediates in furofuran lignan synthesis
Authors: Esteves Ana P. , Lemos Maria A. , Medeiros Maria J. , Rodrigues Lígia M.
Published: December 2009

The synthesis of some intermediates of furofuran lignans was accomplished by a chemical cyclisation reaction using N-ethylpiperidine hypophosphite and azobisisobutyronitrile. This reaction afforded the 5- exo-dig cyclic compound as the major product along with another isomeric cyclic compound which possess an endocyclic double bond. A brief discussion is presented to explain the formation of these isomeric cyclic compounds by a base-catalysed tautomerism mechanism. Some structural aspects are discussed based on nuclear magnetic resonance data.
SmI3 mediated reginospecific Michael addition of ω-bromo-acetophenone to α,β-unsaturated alkynones
Authors: Zheng Xingliang , Zhang Yongmin
Published: December 2009

SmI3 mediated regiospecific Michael addition of ω-bromo-acetophenone to α,β-unsaturated alkynones was investigated. A new method for the synthesis of 1,5-dicarbonyl compounds was put forward. This reaction suffers from the influence of solvents seriously.
Acetylation reactions of amines with ethyl acetate catalysed by ytterbium trifluoromethethanesulfonate
Authors: Su Weike , Cai Hongfei
Published: December 2009

Catalytic amounts of ytterbium trifluoromethethanesulfonate [Yb(OTf)3] have been used to catalyse the acetylation reactions of amines with ethyl acetate under mild and neutral conditions.
Photochemically Catalysed Diels–Alder Reaction of N-arylimines by 2,4, 6-triphenylpyrylium Salt: Synthesis of Furo- and Pyranoquinoline Derivatives
Authors: Zhang Wei , Guo Yanping , Yang Li , Liu Zhong-Li
Published: December 2009

Photochemically promoted Diels–Alder reactions of N-arylimines with 2,3-dihydrofuran and 3,4-dihydro-2 H-pyran were achieved by using 2,4,6-triphenylpyrylium tetrafluoroborate as a catalyst to produce the corresponding furo- and pyranoquinolines in high yield.
Organic reactions in aqueous media: I2-in-water-catalysed rapid and chemoselective oxathioacetalisation of aldehydes under mild conditions
Authors: Bandgar B.P. , Bettigeri Sampada V.
Published: December 2009

I2 in water is found to be an efficient catalyst for the chemoselective protection of both aliphatic and aromatic aldehydes as 1,3-oxathioacetals under mild conditions. Fast reactions and excellent yields of pure products using an inexpensive and easily available catalyst and solvent are important features of this method.
A convenient one-pot synthesis of 3-arylazo derivatives of azino[b][1,2,4,5]tetrazines
Authors: Shawali Ahmad S. , Sayed Abdelwahed R.
Published: December 2009

The reactions of 3-chloro-1,5-diarylformazans 1 with 3-amino-2-thiouracils 2(4) and 3-amino-2-thioxo-6-methyl-1,2, 4-triazin-5(4H)-ones 6 and their methylthio derivatives 3(5) and 7, respectively provide easy access to synthesis of 3-arylazo derivatives of 1,4-dihydro-1,8-disubstituted pyrimido[1,2-b][1,2,4,5]tetrazin-6-ones 8(9) and 1,4-dihydro-1-aryl-7-methyl[1,2,4]triazino[4,3-b][1,2,4,5]-tetrazin-6-ones (10), respectively.
Formation of benzil diimines by microwave-assisted reaction of benzil with aromatic amines on alumina surface without solvent
Authors: Singh G.S. , Mahajan D.S.
Published: December 2009

The microwave-assisted solvent-free reaction of benzil with aromatic amines (in 1: 2 molar ratio) on an alumina surface for 4 min affords benzil diimines (1,2,3,4-tetraaryl-1,4-diaza-1,3-butadienes).
Synthesis of some new 6-substituted quinazolino[4,3-b]quinazolin-8-ones under solvent-free conditions
Authors: Azizian Javad , Mohammadi Ali A. , Karimi Ali R. , Mohammadizadeh Mohammad R.
Published: December 2009

A facile and rapid synthesis of some new 6-substituted quinazolino[4,3- b]quinazolin-8-ones derivatives was investigated. The synthesis involved two-step condensation from isatoic anhydride. The products were obtained by condensation of 2-( o-aminophenyl)-4(3 H)-quinazolinone and ortho-esters in the absence of organic or inorganic reagents in solvent-free conditions under microwave irradiation.
Bismuth triflate catalysed one-pot synthesis of tetrahydrochromanoquinolines
Authors: Babu K. Suresh , Raju B. China , Rao A. Sridhar , Kumar S. Praveen , Rao J. Madhusudana
Published: December 2009

An efficient one-pot synthesis of tetrahydrochromano[4,3- b]quinolines using bismuth triflate as the catalyst at room temperature is described.
Photochromism of several synthesised 1,3-diazabicyclo[3,1,0]hex-3-ene derivatives
Authors: Mahmoodi Nosrat O. , Zanjanchi Mohammad A. , Kiyani Hamzeh
Published: December 2009

Several 1,3-diazabicyclo[3,1,0]hex-3-ene derivatives with varying substitutions such as 9H-fluorenyl, 4-(cyclohexyl-phenyl)-2-methyl, 4-cyclohexyl phenyl, 2-phenyl-2-methyl, and 2-cyclohexyl-2-phenyl that behave as ‘intelligent material’ are reported.
Reformatsky reaction of α-chloroesters with carbonyl compounds with commercially available zinc
Authors: Chavan Subhash P. , Shivasankar K. , Sivappa R.
Published: December 2009

The condensation of α-chloroesters with aliphatic as well as aromatic ketones with commercially available zinc without any external metal additives is described.
Synthetic Studies and Structural Aspects of Some Metallacyclic Compounds of Germanium(IV) Incorporating Nitrogen, Oxygen and Sulfur: 1. Reactions of Germanium(IV) isopropoxide with diols and crystal structure of a diolato bridged germanium(IV) compound [Ge2(O2C2H4)4]
Authors: Pathak Madhvesh , Bohra Rakesh , Mehrotra R.C. , Lorenz Ingo-Peter , Piotrowski Holger
Published: December 2009

Germanium(IV) diolates of the type [(OPri)4-2 nGe(O-G-O) n] ( n = 1, 2) have been prepared by the reaction of Ge(OPri)4 with the corresponding diols in 1:1 and 1:2 molar ratios in anhydrous benzene. All these compounds are colourless viscous liquids except the bis(ethanediolato)germanium(IV), which is a white solid. They have been characterised by elemental analysis and IR and NMR (1H and 13C) spectroscopy. Prismatic crystals of [Ge2(O2C2H4)4] were separated out when [(OPri)2Ge(O2C2H4)] was kept for about 3 weeks at room temperature. Single crystal X-ray diffraction study indicates that it is a unique diolato bridged compound in which the geometry around the germanium atom is a distorted trigonal bipyramid of oxygen atoms which belong to one chelating diolato-O,O′ and to a second η1–O, μ2(η1–O′) bound diolato group.
The synthesis of novel benzocyclobutene monomers containing the squaric acid unit
Authors: Yang Jun-xiao , Chen Wen , Zhu Fang-hua , Su Xiao-yu , Xie Ru-gang , Li Bo , Zhang Lin
Published: December 2009

Several novel benzocyclobutene monomers containing squaric acid unit have been synthesised. They were characterised by IR, 1H NMR, MS, UV-vis and have been element analyses and some have potential applications in polymer type organic electroluminescent materials.
A novel synthesis of tri-and tetra-phenylpyrylium perchlorates from phenyl-substituted cyclopentadienes
Authors: Gong Wei-Tao , Li Xin-Cheng , Ning Gui-Ling , Lin Yuan
Published: December 2009

A route to synthesise tri- and tetra-phenylpyrylium perchlorates from phenyl-substituted cyclopentadienes by treatment with perchloric acid and air is described.
Gewald Synthesis of 2-aminothiophenes on a Soluble Polymer-support
Authors: Zhang Haiqing , Yang Guichun , Chen Jianian , Chen Zuxing
Published: December 2009

A variety of polysubstituted thiophenes have been prepared via a solvent-free one-pot microwave assisted Gewald reaction using poly (ethylene glycol) as a soluble polymer support.
Synthesis of α-iodoacetates from alkenes by cadmium acetate catalysed Woodward's reaction
Authors: Myint Yi Yi , Pasha M. A.
Published: December 2009

Alkenes on treatment with iodine and cadmium acetate in acetic acid give α-iodoacetates in high yields. The reaction is facile and α-iodoacetates are obtained from both acyclic and cyclic alkenes within 5–30 min.
Kinetics and mechanism of the oxidative regeneration of carbonyl compounds from phenylhydrazones by [bis(trifluoroacetoxy)iodo]benzene
Authors: Kansara Alpna , Sharma Pradeep K. , Banerji Kalyan K.
Published: December 2009

The oxidation of several aldo- and keto-phenylhydrazones by [bis(trifluoroacetoxy)iodo]benzene (TFAIB), in aqueous acetic acid leads to the regeneration of the parent carbonyl compounds. The reaction exhibits a first order dependence on both the phenylhydrazone and TFIAB. The oxidation of ketoximes is slower than that of aldoximes. The oxidation of aliphatic phenylhydrazones correlates well in terms of Pavelich–Taft dual substituent-parameter equation. The low positive value of the polar reaction constant indicates a nucleophilic attack by TFIAB on the carbonyl carbon. The reaction is subject to steric hindrance by the alkyl group. A mechanism involving the formation of a cyclic activated complex in the rate-determining step is proposed.
An expeditious synthesis of thiazolidinones and tetathiazanones
Authors: Rawal Ravindra K. , Srivastava Tumul , Haq W. , Katti S. B.
Published: December 2009

In the present study, 4-thiazolidinones have been assembled by HBTU mediated three-component reaction of amine, aldehyde and mercapto acid derivatives at room temperature. The final compounds are obtained in excellent yields within 30 minutes.
Synthesis of dinorcholane and 5β-cholane derivatives
Authors: Nahar Lutfun , Turner Alan B.
Published: December 2009

The convenient synthesis of seven dinorcholane and 5β-cholane derivatives, 3β-acetoxy-23,24-dinorchol-5-en-22-oyl methoxy anhydride (2), 3β-acetoxy-23,24-dinorchol-5-en-22-oyl chloride (3), 3β-acetoxy-23,24-dinorchol-5-en-22-ol (4), 3α-acetoxy-5β-cholan-24-oic acid (6), 3α-acetoxy-5β-cholan-24-oic acid ethyl ester (7), 3-oxo-5β-cholan-24-oic acid (8) and 3-oxo-5β-cholan-24-oic acid ethyl ester (9) have been described. Full spectroscopic data for these compounds are presented.
A mild and simple synthesis of N-aryl substituted toluenesulfamides under solvent-free conditions
Authors: Zhao Na , Wang Yu-Lu
Published: December 2009

In this paper, a series of N-aryl substituted toluenesulfamides were synthesised by grinding under solvent-free conditions at room temperature. The yields were excellent (88%–97%), and the process is simple.
Preparation of 1-Aryl-2-bromo-3,3-difluorocyclopropenes
Authors: Lin Shaw-Tao , Chen Li-Chwen , Lee Chun-Jen
Published: December 2009

1-Aryl-2-bromo-3,3-difluorocyclopropanes were prepared from the reaction of 2′,2′-difluorostyrene and dibromocarbene instead of from 1-aryl-2-haloacetylenes and difluorocarbene. These results are rationalised by the energy gap between HOMO(styrene), HOMO(acetylene) and LUMO(CX2). The title compounds were converted to methyl arylpropynoate in MeOH solution in quantitative yield.
Three-component condensation of substituted Meldrum's acids with methyl ketones and aminomethylating agent
Authors: Li Jing-Hua , Chen Zhen-Chu , Li Ying
Published: December 2009

Three-component condensation of substituted Meldrum's acids with methyl ketones and aminomethylating agent in present of carboxylic anhydride, such as acetic anhydride, gives 5-(3-oxoalkyl)Meldrum's acids.
X-Ray Crystal Structures of trans-6,13-Dimethyl-6,13-Diamino-1,4,8, 11-Tetraazacyclotetradecane.6HCl.2H2O and its Condensation Product with Pyridine-2-Carboxaldehyde
Authors: Jain Sneh L. , Bhattacharyya Pravat , McLellan Sadie A. , Richens David T. , Lightfoot Philip , Slawin Alexandra M. Z. , Woollins J. Derek
Published: December 2009

The X-ray crystal structures of trans-6,13-dimethyl-6,13-diamino-1,4,8,11-tetraazacyclotetradecane hexahydrochloride dihydrate ( trans-diammac.6HCl.2H2O) and the product 1 derived by condensation of trans-diammac with pyridine-2-carboxaldehyde, have been determined. For 1 intramolecular attack of macrocycle amine nitrogen atoms on the C=N bonds of the intermediate diimine gives a ring-closed tautomeric form, which comprises two imidazolidine rings fused to the macrocycle.
Kinetics and Mechanism of the Reduction of Enneamolybdonickelate(IV) by Sulfite
Authors: Huo Guoyan , Zhou Jianmin , Liu Baosheng
Published: December 2009

The kinetics and mechanism of the reduction of enneamolybdonickelate(IV) by sulfite in acetic acid-ammonium acetate buffer solution was studied by spectrophotometry. The reaction rate law is [Formula: see text]. The rate constants and activation parameters of the rate-determining step were evaluated. A mechanism for this reaction is proposed.
Ionic liquid-Accelerated N-Arylation of Benzoazoles with Diaryliodonium Salts, An Efficient Method for the Synthesis of N-aryl Azoles
Authors: Wang Feng-Yan , Chen Zhen-Chu , Zheng Qin-Guo
Published: December 2009

N-Arylation of benzoazoles with diaryliodonium salts can be performed in good yields in the room-temperature ionic liquid 1–butyl–3–methylimidazolium tetrafluoroborate ([bmim]BF4), which provides an efficient method for the synthesis of N-arylbenzoazoles. The ionic liquid can be recycled and reused.
Fe2(SO4)3·4H2O/Concentrated H2SO4: An Efficient Catalyst for Esterification
Authors: Liang Yong-min , Xu Qi-hai , Wu Xiao-li , Ma Yong-xiang
Published: December 2009

The mixed catalyst system, Fe2(SO4)3·4H2O / concentrated H2SO4 has been applied to catalyse effectively the esterification of α,β-unsaturated acids, aliphatic acids and heterocyclic aromatic acids with ethanol and methanol.
Neodymium Triflate as a Recyclable Catalyst for Chemoselective Thioacetalisation
Authors: Kanta De Surya
Published: December 2009

Neodymium triflate has been found to be an efficient and recyclable catalyst for the chemoselective protection of aldehydes.
α-Enones in Heterocyclic Synthesis, Part I. Classical Synthetic and Environmentally Friendly Synthetic Approaches to Alkyl and Acyl Azoles and Azines
Authors: Al-Shiekh Mariam A. , El-Din Abdellatif M. Salah , Hafez Ebtisam A. , Elnagdi Mohamed H.
Published: December 2009

The utility of 1- N,N-dimethylaminopent-1-en-3-one and 1-(4-acetylphenyl)-3-dimethyl aminopropenone in the synthesis of several new azolotriazine, pyrazolo[3,4- d]pyridazine, isoxazolo[3,4- d]pyridazine, azolopyrimidine and pyridine derivatives by conventional heat and also on microwave irradiation, is reported.
An unusual hydroboration of 3-hydroxy-3-methyl-Δ4-steroids
Authors: Uyanik Cavit , Hanson James R. , Nisius Lydia , Hitchcock Peter B.
Published: December 2009

Hydroboration of 3-hydroxy-3-methyl-Δ4-steroids, and oxidation of the borane with alkaline hydrogen peroxide, has been shown by X-ray crystallography to give 4β-hydroxy-3α-methyl-5β(H)-steroids irrespective of the stereochemistry at C-3.
Pinacol coupling of aromatic aldehydes mediated by Zn in aqueous oxalic acid under ultrasound irradiation
Authors: Li Ji-Tai , Chen Yan-Xue , Yang Jin-Hui , Li Tong-Shuang
Published: December 2009

Pinacol coupling of aromatic aldehydes mediated by Zn powder in aqueous oxalic acid gives the corresponding pinacols in 33–83% yields within 2.5 h at r.t. under ultrasound irradiation.
Mechanism of hydrogenation of [60]fullerene with Zn-conc. HCl
Authors: Zhang Jun-Ping , Wang Nai-Xing , Xing Ya-Lan , Yu An-Guang , Yang Yun-Xu , Wang Wu-Wei , Sheng Rui-long
Published: December 2009

A plausible mechanism for hydrogenation of [60]fullerene with Zn-conc. HCl is given and it is confirmed by synthesis of C60H36 by reaction of [60]fullerene and Zn–ZnCl2–H2O.
ZrCl4 catalysed solvent free synthesis of coumarins
Authors: Gangadasu B. , Narender P. , Raju B. China , Rao V. Jayathirtha
Published: December 2009

ZrCl4 is an efficient catalyst in the Pechmann condensation of phenols with ethyl acetoacetate and propynoic acid under solvent free conditions leading to formation of coumarins in very good yields.
Novel ionic liquids based on the benzimidazolium cation
Authors: Huang Wei-Guo , Zhang Su-Mei , Dai Li-Yi , Shan Yong-Kui
Published: December 2009

A new series of salts, based on the benzimidazolium cation (Bim) and some common anions have been prepared. The salts were characterised by DSC, NMR, IR, elemental analysis and thermogravimetric analysis. They showed different properties such as melting point, thermal stability, multiple phase behaviour, and solubility properties compared to salts of the imidazolium cation.
Studies on crystal structure of inclusion chiral crystal of (S)-α-cyclopentyl-α-hydroxyl-α-thienylacetic acid with (R)-α-methyl benylamine
Authors: Liu He , Liu Chun-he , Han Xiang-Yu , Zhong Bo-Hua , Liu Ke-Liang
Published: December 2009

The optically active α-cyclopentyl- α-hydroxyl-α-thienylacetic acid is obtained by the optical resolution of racemates with the chiral host α-methylbenylamine. The structure of the inclusion salt complex of two compounds was first elucidated by X-ray analysis.
Potassium fluoride/alumina mediated simple synthesis of Hantzsch 1, 4-dihydropyridines
Authors: Aydin Fatma , Ozen Recep
Published: December 2009

A general and practical technique to achieve synthesis of 1,4-dihydropyridines in excellent yields has been investigated using potassium fluoride/alumina (KF/Al2O3) as a solid base. The ammonia was obtained either from thermal decomposition of ammonium acetate or by passing ammonia gases in the form of bubbled through hetereogenous reaction medium using an apparatus.
The cyclisation of humulene 6,7- and 9,10-epoxides catalysed by tetracyanoethylene
Authors: Hanson James R. , Hitchcock Peter B. , Macias-Sanchez Antonio J. , Mobbs Daniel J.
Published: December 2009

The cyclisation of humulene 6,7- and 9,10-epoxides catalysed by methanolic tetracyanoethylene has been examined and the structure of a cyclisation product established by X-ray crystallography.
Oxidative Deoximation by Supported Bismuth (III) Nitrate Mediated by DABCO under Microwave Irradiation
Authors: Niaki Taraneh T. , Oskooiee Hossein A. , Heravi Majid M. , Miralaee Bahareh
Published: December 2009

A mild, efficient, rapid and eco-friendly method for the direct conversion of oximes to carbonyl compounds upon treatment with bismuth(III) nitrate supported onto silica gel mediated by DABCO under microwave irradiation is described.
Thioacetamide catalysed transformation of nitriles to 2-substituted imidazolines
Authors: Dash P. , Kudav D. P. , Parihar J. A.
Published: December 2009

The reaction of various nitriles with ethylenediamine in presence of thioacetamide as catalyst has been studied.
Theoretical investigation of the interaction of uracil and mono hydrated uracil – water complexes with alkali metals
Authors: Ghiasi Reza , Monajjem Majid , Asadian Farah , Passdar Hodar
Published: December 2009

Quantum chemistry calculations have been applied in order to explore the interaction of alkali metals with oxo groups of uracil. The optimised geometries, harmonic vibrational frequencies and the energies of uracil, metalated uracil, monohydrated uracil and monohydrated metalated uracil have been calculated. The calculations show that interaction of metals with uracil through O3 (UO3) is stronger than the interaction of metals with O1 (UO1). The presence of water stabilises the UO1, UO3 structures. In mono-hydrated uracil the stability of UO3W rather than UO1W is more than for non hydrated spices. Calculations show that after monohydration, the frequency shift of the stretching vibrations of N6-H is related to the atomic number of the metal.