bluuebunny/crossref_metadata_2025 huggingface dataset:
Quantitative Hydrogen Chloride Detection in Combustion Environments Using Tunable Diode Laser Absorption Spectroscopy with Comprehensive Investigation of Hot Water Interference
Authors: Weng Wubin , Larsson Jim , Bood Joakim , Aldén Marcus , Li Zhongshan
Published: January 2022

Hydrogen chloride (HCl) monitoring during combustion/gasification of biomass fuels and municipal solid waste, such as polyvinyl chloride (PVC) and food residues, is demanded to avoid the adverse effect of HCl to furnace operation and to improve the quality of the gas products. Infrared tunable diode laser absorption spectroscopy (IR-TDLAS) is a feasible nonintrusive in-situ method for HCl measurements in harsh environments. In the present work, the measurement was performed using the R(3) line of the ν2 vibrational band of HCl at 5739.25 cm–1 (1742.4 nm). Water vapor is ubiquitous in combustion/gasification environments, and its spectral interference is one of the most common challenges for IR-TDLAS. Spectral analysis based on the current well-known databases was found to be insufficient to achieve an accurate measurement. The lack of accurate temperature-dependent water spectra can introduce thousands parts per million (ppm) HCl overestimation. For the first time, accurate spectroscopic data of temperature-dependent water spectra near 5739.3 cm–1 were obtained based on a systematic experimental investigation of the hot water lines in a well-controlled, hot flue gas with a temperature varying from 1100 to 1950 K. With the accurate knowledge of hot water interference, the HCl TDLAS system can achieve a detection limit of about 100 ppm⋅m at around 1500 K, and simultaneously the gas temperature can be derived. The technique was applied to measure the temporally resolved HCl release and local temperature over burning PVC particles in hot flue gas at 1790 K.
Does the Premium Fit the Risk? The Role of Criminal Escalation in Case Processing
Authors: Yan Shi , Walker Jason W.
Published: January 2022

Legal and qualitative studies have highlighted that courtroom actors consider multiple aspects of criminal records. However, most quantitative studies on sentencing only included the number of prior convictions or arrests, with little attention to the seriousness trends of those priors. Taking stock from studies on criminal careers, we used group-based trajectory modeling (GBTM) to identify patterns of escalation and de-escalation among a defendant sample in New York State ( n = 56,017), and then examined the role of trajectory groups in four decision points: dismissal, charge reduction, incarceration, and incarceration length. We found that escalation, de-escalation, and a higher stable level of crime seriousness were associated with less favorable outcomes at multiple decision points.
Visitation Enablers and Barriers: Evaluating the Influences of Practical, Relational, and Experiential Factors on Visitation in Dutch Prisons
Authors: Berghuis Maria , Palmen Hanneke , Cochran Joshua , Nieuwbeerta Paul
Published: January 2022

This paper aims to advance theory and knowledge about prison visitation by organizing prior studies within a framework of visitation enablers and barriers and examining how practical, relational, and experiential factors explain variation in prison visiting among 773 adult males across eight Dutch prisons. Findings suggest that all three domains play out at once to influence visitation. Whether visitors come to visit seems to depend on their relationship with the incarcerated individual, whereas traveling distance is more predictive of how often they visit. Policies that introduce practical barriers can differentially affect visits from specific relationships. Finally, results indicate that incarcerated individuals make decisions about visits based on their in-prison experiences. Policy and research implications are discussed.
The Perception of Automation Reliability and Acceptance of Automated Advice
Authors: Hutchinson Jack , Strickland Luke , Farrell Simon , Loft Shayne
Published: January 2022

Objective

Examine (1) the extent to which humans can accurately estimate automation reliability and calibrate to changes in reliability, and how this is impacted by the recent accuracy of automation; and (2) factors that impact the acceptance of automated advice, including true automation reliability, reliability perception, and the difference between an operator’s perception of automation reliability and perception of their own reliability.

Background

Existing evidence suggests humans can adapt to changes in automation reliability but generally underestimate reliability. Cognitive science indicates that humans heavily weight evidence from more recent experiences.

Method

Participants monitored the behavior of maritime vessels (contacts) in order to classify them, and then received advice from automation regarding classification. Participants were assigned to either an initially high (90%) or low (60%) automation reliability condition. After some time, reliability switched to 75% in both conditions.

Results

Participants initially underestimated automation reliability. After the change in true reliability, estimates in both conditions moved towards the common true reliability, but did not reach it. There were recency effects, with lower future reliability estimates immediately following incorrect automation advice. With lower initial reliability, automation acceptance rates tracked true reliability more closely than perceived reliability. A positive difference between participant assessments of the reliability of automation and their own reliability predicted greater automation acceptance.

Conclusion

Humans underestimate the reliability of automation, and we have demonstrated several critical factors that impact the perception of automation reliability and automation use.

Application

The findings have potential implications for training and adaptive human-automation teaming.
Experimental validation of a quasi-transient coupling approach for the modeling of heat transfer in autoclave processing
Authors: Zhu Junhong , Frerich Tim , Dimassi Adli , Koerdt Michael , Herrmann Axel S.
Published: January 2022

Structural aerospace composite parts are commonly cured through autoclave processing. To optimize the autoclave process, manufacturing process simulations have been increasingly used to investigate the thermal behavior of the cure assembly. Performing such a simulation, computational fluid dynamics (CFD) coupled with finite element method (FEM) model can be used to deal with the conjugate heat transfer problem between the airflow and solid regions inside the autoclave. A transient CFD simulation requires intensive computing resources. To avoid a long computing time, a quasi-transient coupling approach is adopted to allow a significant acceleration of the simulation process. This approach has been validated for a simple geometry in a previous study. This paper provides an experimental and numerical study on heat transfer in a medium-sized autoclave for a more complicated loading condition and a composite structure, a curved shell with three stringers, that mocks the fuselage structure of an aircraft. Two lumped mass calorimeters are used for the measurement of the heat transfer coefficients (HTCs) during the predefined curing cycle. Owing to some uncertainty in the inlet flow velocity, a correction parameter and calibration method are proposed to reduce the numerical error. The simulation results are compared to the experimental results, which consist of thermal measurements and temperature distributions of the composite shell, to validate the simulation model. This study shows the capability and potential of the quasi-transient coupling approach for the modeling of heat transfer in autoclave processing with reduced computational cost and high correlation between the experimental and numerical results.
Numerical analysis and optimization of key parts in the stirred tank based on solid-liquid flow field
Authors: Jiang Hongwan , Yuan Sen , Liu Hao , Li Weiwei , Zhou Xiaorong
Published: January 2022

In order to further improve the mixing performance of the mixing device, the structure of the agitator was optimized, and the effects of the diameter and pitch of the agitator on the solid-liquid suspension characteristics were analyzed by single factor method. Multiple reference frame (MRF), computational fluid dynamics, Euler multiphase flow model and standard K- ε turbulence model were used to investigate the effect of the height from the bottom of the agitator on the suspension characteristics of particles in the agitator was studied. The results show that reducing the height from the bottom of the agitator can promote the suspension of particles at the bottom of the tank, but too low height from the bottom will easily produce mixing dead zone at the bottom of the tank, and cause the accumulation of particles. Reducing the height of the agitator from the bottom will enlarge the clear liquid area of the flow field, cause uneven particle distribution and increase the stirring torque. With the increase of agitator diameter, the critical suspension speed of the flow field decrease, but the stirring power required by the flow field increase. Increasing the blade spacing in a certain range can promote the suspension of particles and make the distribution of particles in the flow field more uniform. Therefore, the mixing power and the uniformity of particle concentration distribution need to be considered together in order to make the mixing device more efficient and energy-saving.
The Missing Piece of the Puzzle: The EMASYA Protocol and Civil-Military Relations in Turkey
Authors: Genç Yılmaz Ayfer
Published: January 2022

The civil-military relations literature on Turkey focuses predominantly on the guardianship role of the Turkish military, its interventions, and the role of the National Security Council as the main institutional mechanism of military tutelage. Yet, the existing studies lack a much-needed focus on the law enforcement or policing missions of the Turkish military. To fill this gap, this study discusses the EMASYA Protocol ( Emniyet Asayiş Yardımlaşma or Security and Public Order Assistance), a secret protocol signed in 1997. Emerging in the context of political instability and military tutelage of the 1990s, the Protocol enabled the military to conduct internal security operations without permission from the civilian authorities. This paper argues that the EMASYA Protocol provided a sphere of “reformulated new professionalism” for the Turkish military, enabled it to specialize in the war against rising internal threats such as reactionary Islam and Kurdish separatism, and created anomalies in civil-military relations in Turkey.
The association between financial strain and volatility in daily relationship uncertainty: A dyadic investigation
Authors: Gajos Jamie M. , Totenhagen Casey J. , Wilmarth Melissa J.
Published: January 2022

Prior research suggests that financial strain negatively impacts relational outcomes and that fluctuations (i.e., volatility) in daily reports of relationship aspects may be detrimental for relational outcomes. Daily relational uncertainty may also be associated with financial stressors; however, little is known about the association between financial strain and levels of daily relational uncertainty, as well as the volatility in day-to-day relational uncertainty. The current study includes both members of 100 adult different-sex couples (relationship length M = 7.0 years, SD = 7.1) who completed 14 days of daily diaries. We examined whether greater baseline financial strain is associated with higher levels of daily relational uncertainty and greater day-to-day volatility in relational uncertainty among actors and partners. Individuals who reported greater financial strain also reported higher overall levels of daily relationship uncertainty, as well as greater volatility in daily relationship uncertainty. The association between actor financial strain and volatility in daily relationship uncertainty was moderated by gender and marital status, such that financial strain was only associated with greater volatility in daily relationship uncertainty for men (but not for women) and for unmarried (but not married) individuals. Evidence for partner effects were also found, where partners’ higher levels of financial strain was associated with less volatility in actors’ daily relational uncertainty; however, this relationship was moderated by income, gender, and marital status. Individuals with lower income levels (versus high income levels) reported less volatility in their daily relationship uncertainty when their partners reported higher financial strain. Males rather than women reported lower volatility in daily relational uncertainty when their partners reported greater financial strain. In addition, unmarried rather than married individuals reported greater volatility in daily relationship uncertainty when their partners reported higher financial strain. Implications for future research and practice are discussed.
Enhancing teachers’ classroom communication skills – Measuring the effect of a continued professional development programme for mainstream school teachers
Authors: Andersson Ketty , Sandgren Olof , Rosqvist Ida , Lyberg Åhlander Viveka , Hansson Kristina , Sahlén Birgitta
Published: January 2022

Continued professional development (CPD), tailored to teachers’ needs and expectations, is required for updated skills and knowledge. In this study, twenty-five teachers working with first and second grade students participated in an 11-week programme focusing on enhancing classroom communication. The participating teachers were randomly assigned to either a direct intervention track (intervention) or a delayed intervention track (waiting control). Teachers’ perceptions of activities and interactions in the classroom and self-efficacy were assessed on three occasions: T1, T2, and T3. The direct intervention track received intervention between T1 and T2, while the delayed intervention track received intervention between T2 and T3. A percentage change score for changes between T1 and T2 was calculated, to compare the direct and delayed intervention tracks and assess any intervention effect. Results revealed no significant difference between the groups, i.e., the intervention had no effect on teacher self-reports. The teachers gave an overall positive evaluation of the CPD. Thematic analyses revealed continued need for professional development and insights into the reciprocal influence of student and teacher behaviour. The quantitative and qualitative results paint somewhat different pictures showing the need of mixed methods when analysing these kinds of data.
MitraClip® procedure as bridge to left ventricular assist device: Enable extracorporeal membrane oxygenation weaning and reduce perioperative risk
Authors: Schmiady Martin O. , Winnik Stephan , Bettex Dominique , Aser Raed
Published: January 2022

Secondary mitral valve regurgitation is a frequent consequence of left ventricular dysfunction in patients with severe heart failure. The management of this disease can be challenging since it often culminates in refractory pulmonary edema and multi-organ failure. We present the case of a 50-year-old male who was admitted in cardiogenic shock following myocardial infarction. After successful revascularization, percutaneous mitral valve repair using the MitraClip® device enabled weaning from extracorporeal membrane oxygenation followed by the implantation of a left ventricular assist device as bridge to transplant.
Activation of the aryl hydrocarbon receptor by clozapine induces preadipocyte differentiation and contributes to endothelial dysfunction
Authors: Fehsel K , Schwanke K , Kappel BA , Fahimi E , Meisenzahl-Lechner E , Esser C , Hemmrich K , Haarmann-Stemmann T , Kojda G , Lange-Asschenfeldt C
Published: January 2022

Background:

The superior therapeutic benefit of clozapine is often associated with metabolic disruptions as obesity, insulin resistance, tachycardia, higher blood pressure, and even hypertension.

Aims:

These adverse vascular/ metabolic events under clozapine are similar to those caused by polycyclic aromatic hydrocarbons (PAHs), and clozapine shows structural similarity to well-known ligands of the aryl hydrocarbon receptor (AhR). Therefore, we speculated that the side effects caused by clozapine might rely on AhR signaling.

Methods:

We examined clozapine-induced AhR activation by luciferase reporter assays in hepatoma HepG2 cells and we proved upregulation of the prototypical AhR target gene Cyp1A1 by realtime-PCR (RT-PCR) analysis and enzyme activity. Next we studied the physiological role of AhR in clozapine’s effects on human preadipocyte differentiation and on vasodilatation by myography in wild-type and AhR-/- mice.

Results:

In contrast to other antipsychotic drugs (APDs), clozapine triggered AhR activation and Cyp1A1 expression in HepG2 cells and adipocytes. Clozapine induced adipogenesis via AhR signaling. After PGF2α-induced constriction of mouse aortic rings, clozapine strongly reduced the maximal vasorelaxation under acetylcholine in rings from wild-type mice, but only slightly in rings from AhR-/- mice. The reduction was also prevented by pretreatment with the AhR antagonist CH-223191.

Conclusion:

Identification of clozapine as a ligand for the AhR opens new perspectives to explain common clozapine therapy-associated adverse effects at the molecular level.
The effects of psilocybin on cognitive and emotional functions in healthy participants: Results from a phase 1, randomised, placebo-controlled trial involving simultaneous psilocybin administration and preparation
Authors: Rucker James J , Marwood Lindsey , Ajantaival Riikka-Liisa J , Bird Catherine , Eriksson Hans , Harrison John , Lennard-Jones Molly , Mistry Sunil , Saldarini Francesco , Stansfield Susan , Tai Sara J , Williams Sam , Weston Neil , Malievskaia Ekaterina , Young Allan H
Published: January 2022

Background:

Psilocybin, a psychoactive serotonin receptor partial agonist, has been reported to acutely reduce clinical symptoms of depressive disorders. Psilocybin’s effects on cognitive function have not been widely or systematically studied.

Aim:

The aim of this study was to explore the safety of simultaneous administration of psilocybin to healthy participants in the largest randomised controlled trial of psilocybin to date. Primary and secondary endpoints assessed the short- and longer-term change in cognitive functioning, as assessed by a Cambridge Neuropsychological Test Automated Battery (CANTAB) Panel, and emotional processing scales. Safety was assessed via endpoints which included cognitive function, assessed by CANTAB global composite score, and treatment-emergent adverse event (TEAE) monitoring.

Methods:

In this phase 1, randomised, double-blind, placebo-controlled study, healthy participants ( n = 89; mean age 36.1 years; 41 females, 48 males) were randomised to receive a single oral dose of 10 or 25 mg psilocybin, or placebo, administered simultaneously to up to six participants, with one-to-one psychological support – each participant having an assigned, dedicated therapist available throughout the session.

Results:

In total, 511 TEAEs were reported, with a median duration of 1.0 day; 67% of all TEAEs started and resolved on the day of administration. There were no serious TEAEs, and none led to study withdrawal. There were no clinically relevant between-group differences in CANTAB global composite score, CANTAB cognitive domain scores, or emotional processing scale scores.

Conclusions:

These results indicate that 10 mg and 25 mg doses of psilocybin were generally well tolerated when given to up to six participants simultaneously and did not have any detrimental short- or long-term effects on cognitive functioning or emotional processing.

Clinical Trial Registration:

EudraCT ( https://www.clinicaltrialsregister.eu/ ) number: 2018-000978-30.
Intervertebral disc degeneration in warmblood horses: Histological and biochemical characterization
Authors: Bergmann Wilhelmina , de Lest Chris van , Plomp Saskia , Vernooij Johannes C. M. , Wijnberg Inge D. , Back Willem , Gröne Andrea , Delany Mark W. , Caliskan Nermin , Tryfonidou Marianna A. , Grinwis Guy C. M.
Published: January 2022

Gross morphology of healthy and degenerated intervertebral discs (IVDs) is largely similar in horses as in dogs and humans. For further comparison, the biochemical composition and the histological and biochemical changes with age and degeneration were analyzed in 41 warmblood horses. From 33 horses, 139 discs and 2 fetal vertebral columns were evaluated and scored histologically. From 13 horses, 73 IVDs were assessed for hydration, DNA, glycosaminoglycans, total collagen, hydroxyl-lysyl-pyridinoline, hydroxylysine, and advanced glycation end-product (AGE) content. From 7 horses, 20 discs were assessed for aggrecan, fibronectin, and collagen type 1 and 2 content. Histologically, tearing of the nucleus pulposus (NP) and cervical annulus fibrosus (AF), and total histological score (tearing and vascular proliferation of the AF, and chondroid metaplasia, chondrocyte-like cell proliferation, presence of notochordal cells, matrix staining, and tearing of the NP) correlated with gross degeneration. Notochordal cells were not seen in IVDs of horses. Age and gross degeneration were positively correlated with AGEs and a fibrotic phenotype, explaining gross degenerative changes. In contrast to dogs and humans, there was no consistent difference in glycosaminoglycan content and hydration between AF and NP, nor decrease of these variables with age or degeneration. Hydroxylysine decrease and collagen 1 and AGEs increase were most prominent in the NP, suggesting degeneration started in the AP. In caudal cervical NPs, AGE deposition was significantly increased in grossly normal IVDs and total collagen significantly increased with age, suggesting increased biomechanical stress and likelihood for spinal disease in this part of the vertebral column.
Impact of Ursodeoxycholic Acid in Critically Ill Patients With Sepsis: A Retrospective Study
Authors: Al Sulaiman Khalid , Kharbosh Abdullah , Bin Salah Khalid , Alsulaiman Thamer , Al Andas Norah , Aljuhani Ohoud , Vishwakarma Ramesh
Published: January 2022

Background: Using ursodeoxycholic acid (UDCA) in critically ill patients as adjunctive therapy for sepsis/septic shock in neonates and children is controversial, while it has not been extensively investigated in adults. This study aims to assess the effect of UDCA use on the early resolution of sepsis/septic shock in critically ill adult patients. Method: A retrospective study of critically ill adult patients in the intensive care unit (ICU) admitted with sepsis/septic shock at King Abdulaziz Medical City. Based on their usage of UDCA, patients were categorized into two groups. A total of 88 patients were included for analysis after matching, based on severity of illness scores within 24-hours of ICU admission. The primary outcome was to assess the effect of UDCA on the severity and resolution of shock at day three of ICU admission. The secondary outcomes were 30-day in-hospital mortality, mechanical ventilation (MV) duration, and ICU length of stay (LOS). Results: Out of the 88 patients matched, 44 patients (50%) received UDCA during the study period. Using UDCA was neither associated with improvement in Sequential Organ Failure Assessment (SOFA) score ( p-value: 0.32), inotropes/vasopressors requirement ( p-value: 0.79), Glasgow Coma Scale (GCS) ( p-value: 0.59) nor total bilirubin levels ( p-value: 0.79) at day three compared with the control. There was a significant association between using UDCA and improvement in PaO2/FiO2 ratio ( p-value: 0.01) and early extubation at day three ( p-value: 0.04). Conclusion: Using UDCA in critically ill patients with sepsis/septic shock was not associated with improvement in shock severity and resolution. However, patients who received UDCA were more likely to be extubated and not require MV on day three of ICU admission.
Determination of loading capacity index of a continuous miner in soft rock roadway and virtual test method
Authors: Zhang Hong , Chen You , Zhang Zhihong , Yan Honghong
Published: January 2022

To improve the loading efficiency and reduce energy consumption of a continuous miner in soft rock roadway, a seven-arm star wheel designed with Gaussian fitting method was proposed, and a coal loading model of the continuous miner star wheel loading mechanism was reconstructed with EDEM software. The loading capacity of the seven-arm star wheel and the three-arm star wheel of the EML340 continuous miner at different working speeds were studied respectively. The scientific and reasonable identification index was formulated and the index evaluation system of loading star wheel was established. It has been found that the performance of the loading star wheel is a collection of various identification indicators, the coal returning mass reducing the loading efficiency and increasing unnecessary energy consumption, therefore, it is difficult to identify by a single index. Loading coal and rock by the star wheel is a process that consumes energy and pays attention to output, therefore, the identification index should include two kinds of efficiency parameters and energy parameters. Rake coal torque and loading specific energy consumption have reflected the degree of energy utilization, which can be comprehensively used for preliminary design of the star wheel. The performance parameters such as loading power and loading efficiency are reliable indicators for designing and performance evaluation of the star wheel. Based on the statistical analysis of the test data, compared with the three-arm star wheel of the EML340 continuous miner, the loading efficiency of the seven-arm star wheel has been significantly improved. The loading power for coal loading has been reduced by 46%. The feasibility of the Gaussian design method of loading star wheel has been verified.
Research on compact propulsion system dynamic model based on deep neural network
Authors: Fang Juan , Zheng Qiangang , Zhang Haibo
Published: January 2022

The on-board dynamic model is the basis of numerous advanced control technologies for modern aero-engine, and its accuracy and real-time performance are two crucial indicators. Since the simulation accuracy declines with the deviation from the ground point of the conventional compact propulsion system dynamic model (CPSDM), an improved CPSDM (ICPSDM) based on deep neural network is proposed in this paper. First, the K-means algorithm is utilized to get the sampling point, and the engine simulation data is collected in the cluster centers. Then, the batch normalize deep neural network (BN-DNN) is applied to build the ICPSDM, which can shorten the training time tremendously. The simulation results show that, in the same simulation environment, the accuracy of turbine inlet temperature T 4 , fan surge margin SMc, thrust F, and specific fuel consumption SFC calculated by ICPSDM are 11.04, 3.17, 1.89, and 1.98 times of CPSDM, respectively, at off-design point, and the real-time performance of ICPSDM is more than 30 times faster than the component-level model.
A Caribbean Visionary and His Literary Collection, Karlene Saundria Nelson
Authors: Nelson Karlene Saundria
Published: January 2022

The voices of West Indian writers in the 1950s changed the landscape for Literature emerging out of the West Indies. These powerful literary voices were a means of creating and recording a facet of West Indian history and cultural heritage. West Indian writers wrote their stories through their own eyes. John Hearne was one of the most eloquent voices among them. He became a known voice in the West Indian literary world, using his recognition to facilitate the indigenous West Indian Literature genre’s development. He was also a prominent Jamaican political and social commentator. The John Hearne archive not only produced an important historical picture of the development of the West Indian Literature genre, but West Indian political history, and changes in the cultural and social fabric of the West Indian society, with special emphasis on Jamaica. This paper aims to present this archive as a fundamental body of primary resources for historical research.
Human Vision Reconstructs Time to Satisfy Causal Constraints
Authors: Bechlivanidis Christos , Buehner Marc J. , Tecwyn Emma C. , Lagnado David A. , Hoerl Christoph , McCormack Teresa
Published: January 2022

The goal of perception is to infer the most plausible source of sensory stimulation. Unisensory perception of temporal order, however, appears to require no inference, because the order of events can be uniquely determined from the order in which sensory signals arrive. Here, we demonstrate a novel perceptual illusion that casts doubt on this intuition: In three experiments ( N = 607), the experienced event timings were determined by causality in real time. Adult participants viewed a simple three-item sequence, ACB, which is typically remembered as ABC in line with principles of causality. When asked to indicate the time at which events B and C occurred, participants’ points of subjective simultaneity shifted so that the assumed cause B appeared earlier and the assumed effect C later, despite participants’ full attention and repeated viewings. This first demonstration of causality reversing perceived temporal order cannot be explained by postperceptual distortion, lapsed attention, or saccades.
Combatting exploitation of migrant temporary agency workers through sectoral self-regulation in the UK and the Netherlands
Authors: Been Wike , de Beer Paul
Published: January 2022

The recent growth of precarious work has sparked a vivid debate on whether this tendency can be reversed by the social partners through sectoral self-regulation. In this sectoral case study of the temporary work agencies sector in the United Kingdom and the Netherlands, the views, approaches, power and interaction between trade unions and employers’ organizations are studied in the context of increasing labour migration in the decade following European Union enlargement. The results show that the employers’ organizations have been leading actors in self-regulation, seeking collaboration with trade unions in the Netherlands. In both countries, trade unions have taken an inclusive approach but had little power to affect the deterioration of employment conditions. It has proven difficult to the social partners to reverse the process of increasing precarious work and exploitation. Strict regulatory frameworks imposed by the government are needed to turn a vicious circle into a virtuous one.
Carl von Linné: The Development of the Idea of Binomial Nomenclature
Authors: Yucesan Emrah
Published: January 2022

Due to binomial classification system defined by Carl von Linné, it has been shown that living things that were thought to be independent from each other are actually in a relationship. This "binomial classification" idea corresponds to a leap in the history of human thought. Carl von Linné's original idea is a product of the specific conditions of the period, particularly the renaissance and reform movements and geographical discoveries, rather than an idea he produced alone. These movements are part of a chain of ideas that stretches from antiquity to the Medieval and then to the period called the Enlightenment. The aforementioned transformations generally affected the scientist, albeit indirectly, even in geographies far from Sweden, where Carl von Linné spent most of his life. As such, the binomial classification system stands before us as a result of scientific breakthroughs in central Europe. In this study, it will be tried to be explained by taking the opus magnum of Carl von Linne as an example, taking into account the course of scientific developments, which we can attribute to the European civilization, and the philosophical and social texture.
Risk of Malocclusion Among Patients Undergoing Single-Stage Versus Two-Stage Cleft Palate Repair
Authors: McCrary Hilary , Torrecillas Vanessa , Pollard Sarah Hatch , Collingridge Dave S. , Yamashiro Duane , Skirko Jonathan R.
Published: January 2022

Objective

Evaluate impact of single-stage versus staged palate repair on the risk of developing malocclusion among patients with cleft palate (CP).

Design

Retrospective cohort study 2000–2016

Setting

Academic, tertiary children’s hospital.

Patients

Patients undergoing CP repair between 1999–2015.

Interventions

CP repair, categorized as either single-stage or staged.

Main Outcome Measure

Time to development of Class III malocclusion.

Results

967 patients were included; 60.1% had a two-stage CP repair, and 39.9% had single-stage. Malocclusion was diagnosed in 28.2% of patients. In the model examining all patients at ≤5 years ( n = 659), patients who were not white had a higher risk of malocclusion (HR 2.46, p = 0.004) and staged repair was not protective against malocclusion (HR 0.98, p = 0.91). In all patients >5 years ( n = 411), higher Veau classification and more recent year of birth were significantly associated with higher hazard rates ( p < 0.05). Two-staged repair was not protective against developing malocclusion (HR 0.86, p = 0.60). In the model examining patients with staged repair ≤5 years old ( n = 414), higher age at hard palate closure was associated with reduced malocclusion risk (HR 0.67, p < 0.001) and patients who were not white had increased risk (HR 2.56, p = 0.01). In patients with staged repair >5 years old, more recent birth year may be associated with a higher risk of malocclusion (HR 1.06, p = 0.06) while syndrome may be associated with lower risk of malocclusion diagnosis (HR 0.46, p = 0.07).

Conclusion

Our data suggests that staged CP repair is not protective against developing Class III malocclusion.
High-bandwidth controller design for dual-stage actuator system in hard disk drives
Authors: Yabui Shota , Atsumi Takenori
Published: January 2022

Large-capacity hard disk drives are important for the development of an information society. The capacities of hard disk drives depend on the positioning accuracy of magnetic heads, which read and write digital data, in disk-positioning control systems. Therefore, it is necessary to improve positioning accuracy to develop hard disk drives with large capacities. Hard disk drives employ dual-stage actuator systems to accurately control the magnetic heads. A dual-stage actuator system consists of a voice coil motor and micro-actuator. In micro-actuators, there is a trade-off between head-positioning accuracy and stroke limitation. In particular, in a conventional controller design, the micro-actuator is required to actuate such that it compensates for low-frequency vibration. To overcome this trade-off, this study proposes a high-bandwidth controller design for the micro-actuator in a dual-stage actuator system. The proposed method can reduce the required stroke of the micro-actuator by increasing the gain of the feedback controller of the voice coil motor at low frequencies. Although the voice coil motor control loop becomes unstable, the micro-actuator stabilizes the entire feedback loop at high frequencies. As a result, the control system improves the positioning accuracy compared to that achieved by conventional control methods, and the required micro-actuator stroke is reduced.
Effects of Exposure to COVID-19 News and Information: A Meta-Analysis of Media Use and Uncertainty-Related Responses During the Pandemic
Authors: Chu Tsz Hang , Yeo Tien Ee Dominic , Su Youzhen
Published: January 2022

This meta-analysis integrates 47 empirical studies, comprising 89,826 participants from 21 countries, to examine the cumulative effects and potential moderators of exposure to COVID-19 news and information on attendant emotions, appraisals, and behaviors. Overall media exposure indicated only small positive effect sizes on adverse psychological reactions, though it was moderately and positively associated with disease concern and preventive measures. Social media exposure was associated with all these responses, but traditional news media exposure was only associated with disease concern. The associations between overall media exposure and adverse psychological reactions were moderated by COVID-19 experience, healthcare profession, and country type.
The impact of medication reconciliation and review in patients using oral chemotherapy
Authors: Darcis Emeline , Germeys Jana , Stragier Marnik , Cortoos Pieterjan
Published: January 2022

Background and aim

Verifying and reviewing a patients medication list can detect and reduce drug related problems (DRPs). However little is known about its effects in patients using oral chemotherapy. The aim of this study was to evaluate the impact of these interventions and the adapted Medication Appropriateness Index (aMAI) as a tool to carry out a medication review.

Methods

A case-control study was carried out. The hospital pharmacist performed a medication reconciliation and medication review, using the aMAI tool, in 54 patients starting oral chemotherapy. Discrepancies, DRP's and associated pharmaceutical interventions were reported via the electronic patient record (EPR). After one month, the acceptance rate was measured and the aMAI score recalculated. Kappa statistics were used to test intra- and interrater reliability.

Results

The medication list in the EPR was incomplete in 74,1% of patients with an average of 2.4 errors per patient. After medication review, the aMAI score decreased significantly from 7.2 to 5.4 (SD  =  4,7; p <0.001), indicating an improvement in the appropriateness of the drugs patients were taking. Acceptance rates were 41,4% and 53,2% for advices resulting from medication reconciliation and medication review respectively. Kappa values of 0.90 and 0.70 respectively indicate good intra- and interrater reliability.

Discussion and conclusion

The study shows that medication reconciliation can identify and address discrepancies. Furthermore, medication review seems to ensure that drug treatment better meets patient needs. The aMAI was a reliable tool. Future research will have to determine the clinical relevance of these interventions.
A Survey of the Experiences of Paraprofessionals With Roles, Training, and Communication When Working With Students With Autism
Authors: Morin Kristi L. , Nowell Sallie , Steinbrenner Jessica , Sam Ann , Waters Victoria , Odom Samuel L.
Published: January 2022

Paraprofessionals are critical members of instructional teams for students with autism; however, little is known about their job preparation and professional development needs. This study addressed the gap in the literature by surveying 325 paraprofessionals in public school settings in the United States and Guam who reported working with students with autism. Data were gathered on paraprofessionals’ (a) roles and responsibilities, (b) applied knowledge from different types of professional development, (c) perceived barriers to professional development, and (d) types and timing of communication with their supervising teachers. The results of this study have direct implications for individuals interested in developing a model of professional development that will meet the unique needs of paraprofessionals who work with students with autism.
Cranial Fasciitis in Children: Expanding the Spectrum of USP6-Associated Clonal Transient Neoplasms
Authors: Malik Faizan , Bernieh Anas , El Jamal Siraj M. , Saad Ali G.
Published: January 2022

Background: Cranial fasciitis (CF) is a benign (myo)fibroblastic proliferation of children. Typical presentation consists of a rapidly growing solitary mass on the temporal or parietal cranium in the first 2 years of age. CF is characterized by a rapid growth followed by a relative slowdown and even growth arrest. The finding of somatic USP6 gene rearrangements demonstrating clonality in CF together with its clinical behavior places it in the category of diseases recently termed “transient neoplasia.”

Methods: Histological, immunohistochemical, and molecular findings of 18 patients with CF were retrospectively studied.

Results: The tumor typically presented as a painless rapidly enlarging mass in the temporal region. Sixty-six percent of the cases harbored USP6 gene rearrangement. Nine patients were treated with gross total resection (GTR) and 9 with subtotal tumor resection (STR). Two patients treated with GTR had recurrence. Five patients treated with STR had progression-free disease for at least 10 months after surgery and in four patients the tumor regressed spontaneously a median 16 months after surgery.

Conclusions: In this largest series to date, we reported the clinicopathological, immunohistochemical, and molecular findings of 18 pediatric cases of CF with emphasis on the clinical growth pattern of these tumors.
Re-examining the Use of Force Continuum: Why Resistance is Not the Only Driver of Use of Force Decisions
Authors: McLean Kyle , Alikhan Arif , Alpert Geoffrey P.
Published: January 2022

Policing research and use of force policies have been guided by the continuum model for the past several decades. The continuum specifies a relationship between the amount of resistance a suspect presents and the amount of force that an officer should use to respond to or overcome a given level of resistance. In this paper, we show that resistance alone is an insufficient indicator of the necessity and level of force to be used both conceptually and empirically. We argue for the inclusion of considerations of perceived threat in the analysis of use of force incidents—both in policy and in research. Our analysis also reiterates the importance of police culture in understanding use of force decisions.
Differential Effect of Non-Purified and Semi-Purified Standard Diets on Kynurenine and Peripheral Metabolites in Male C57BL/6J Mice
Authors: Yajima Yuhei , Okuno Alato , Nakamura Isamu , Miyazaki Teruo , Honda Akira , Toyoda Atsushi
Published: January 2022

The kynurenine (Kyn) pathway plays crucial roles in several inflammation-induced disorders such as depression. In this study, we measured Kyn and other related molecules in the blood plasma, brain, and urine of male C57BL/6J mice (B6) fed non-purified (MF) and semi-purified (AIN-93G and AIN-93M) standard rodent diets. Mice fed MF had increased plasma Kyn levels compared with those on AIN93-based diets, as well as decreased hippocampal Kyn levels compared with those fed AIN-93G. Previous studies showed that branched chain amino acids (BCAAs) suppress peripheral blood Kyn transportation to the brain, but plasma BCAA levels were not significantly different between the diet groups in our study. Urine metabolome analysis revealed that feed ingredients affected the excretion of many metabolites, and MF-fed mice had elevated excretion of kynurenic and quinolinic acids, pivotal metabolites in the Kyn pathway. Collectively, the level of critical metabolites in the Kyn pathway in the central and peripheral tissues was strongly affected by feed ingredients. Therefore, feed selection is a critical factor to ensure the reproducibility of experimental data in studies involving rodent models.
The impact of the acoustic environment on human emotion and experience: A case study of worship spaces
Authors: Algargoosh Alaa , Soleimani Babak , O’Modhrain Sile , Navvab Mojtaba
Published: January 2022

People’s interactions with the environment shape their experiences. Thus, understanding these interactions is critical to enhancing human well-being. Aural attributes play a significant role in shaping the perception of space in addition to visual attributes. It is well known that sounds evoke an emotional response, but less is known about how the acoustic characteristics of environments reinforce such an emotional impact. By adopting virtual reality as a platform for recreating 3D sounds and 360° visuals of built environments of worship spaces as case studies, this study aims to investigate the influence of the acoustic environment considering audiovisual congruency on enhancing the human experience through self-report and physiological response analysis. It also examines the role of cultural background in terms of familiarity with the acoustic environment. The convergent mixed-methods approach, merging both quantitative and qualitative analysis, provides a deep understanding of the role of the acoustic environment in enhancing the auditory experience. The results show that the acoustic environment and audiovisual congruency amplify the intensity of the emotional impact, and the amplification of the impact can vary depending on the acoustic environment of the building. They also reveal that familiarity with sound and acoustic characteristics can increase this impact.
Servants of two (or more) masters: Accounting for the complexity of intraparty candidate selection methods
Authors: Tuttnauer Or , Rahat Gideon
Published: January 2022

Intraparty candidate selection methods are the drivers of many topics of interest to political scientists. Their operationalization, however, is made complicated because they tend to involve multiple selectorates that differ in their levels of inclusiveness and centralization and that play various roles within the process. This complexity poses a challenge for large- n comparative studies. Drawing on the Political Parties DataBase Round Two to analyze candidate selection methods in 184 parties from 35 democracies, we highlight the inadequacy of the currently available measures to correctly account for this complexity in large- n studies and offer improvements on this front. Specifically, we propose a continuous measure of inclusiveness that better captures the complexity of candidate selection methods and a new measure of complexity to facilitate future analyses into this feature. We recommend that scholars in other cross-national projects consider adopting similar or improved coding strategies in order to better capture these complexities.
“The effects of family therapeutic interventions on mental health and quality of life of children with cancer: A systematic review”
Authors: Vasilopoulou Konstantina , Skoutari Angeliki , Siomos Konstantinos , Christodoulou Nikolaos
Published: January 2022

Background:

The diagnosis of a childhood malignancy and the following period are very stressful for the little patient and the whole family. Depression, anxiety, and poor quality of life (QoL) are some of the negative effects of pediatric cancer to the children and their parents. Family therapeutic interventions aim to improve mental health and QoL of these children.

Methods:

A systematic search of the electronic database PubMed was conducted for articles that studied the effect of family therapeutic interventions on mental health and QoL of children with cancer.

Results:

A total of 634 articles were evaluated, of which 10 articles met the inclusion criteria. A percentage of 70% of the studies, representing seven different types of interventions, seemed to be beneficial for the participant’s mental health and QoL. The remaining three studies did not significantly improve mental health and QoL.

Conclusion:

The results of our review indicate that family psychosocial interventions are beneficial for children with cancer. These children and their families are a growing population requiring more patient-centered, time flexible interventions which may enhance family bonding and patients’ positive emotions.