bluuebunny/crossref_metadata_2025 huggingface dataset:
Meanings of the simple declarative Arabic sentence syntax from the perspective of the magic subject theory in the renewal of Arabic grammar
Authors: الخفاجي تومان
Published: August 2023

The research reached a number of results, the most important of which are the following:
1- This renewal attempt revealed the size of the problem that occurred in the origins of traditional grammar, and it infiltrated its branches, and its errors continued to multiply until now, and the reform attempts that stood in its way after Sebawayh were unable to stop this deviation. It is only a bold, serious attempt that relies on certain principles and a deductive terminological system based on proven hypotheses that produces a set of new procedural terms stemming from the nature of the Arabic language while performing its communicative function. Therefore, all attempts to reform or renew grammar failed. ancient and modern ones; Because it remained imprisoned in the old curricula that were not armed with what modern sciences are armed with, based on an accurate, coherent and clear experimental method that provides an easy-to-apply model.
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Polish ethics and medicine in XXI century (opportunities and threats)
Authors: Sytnik-Czetwertyński Janusz , Skowron Adam , Pinkas Jarosław , Ostrowski Janusz
Published: August 2023

Despite medical breakthroughs, mankind is still unable to effectively counter health challenges. The COVID-19 pandemic is a case in point. It has failed to predict its effects and the extent to which it is spreading, even though statistical studies hade indicated that it may be coming. The purpose of this article is to identify medical and ethical issues arising from the difference between the current state of medical knowledge and the associated challenges.
The problem of paramedicine in Poland – from the ethical point of view
Authors: Sytnik-Czetwertyński Janusz , Skowron Adam , Ostrowski Janusz , Pinkas Jarosław
Published: August 2023

The aim of this article is to analyze the concept of "paramedicine" and to present it in a mainly ethical aspect. The problem will be considered mainly in the context of Poland and Polish legal regulations. After an attempt to define what paramedicine is, an ethical and legal analysis of the problem follows. The whole article ends with conclusions.
History of the School of Public Health at the Centre of Postgraduate Medical Education (1971 to 2021)
Authors: Ostrowski Janusz , Zgliczyński Wojciech Stefan , Pinkas Jarosław , Gellert Ryszard
Published: August 2023

The 50th anniversary of the Centre of Postgraduate Medical Education (CMKP) was celebrated in 2021. Since the beginning, the School of Public Health (SZP) has been inseparable linked with the CMKP. Throughout this period, the position of the SZP director has been held by eight persons i.e. Bogusław Kożusznik (1971 to 1977), Marek Sanecki (1978 to 1991), Andrzej Wojtczak (1991 to 1996), Jerzy Leowski (1996 to 2003), Janusz Opolski (2003 to 2004 and 2005 to 2011), Maria Miller (2005 to 2005), Dorota Cianciara (2011 to 2018) and Jarosław Pinkas (since 2018). In the paper, the consecutive directors and the SZP modifications during the period of the recent 50 years is presented.
New legal regulations on current medical problems
Authors: Wrześniewska-Wal Iwona , Hajdukiewicz Dariusz , Augustynowicz Anna , Janiszewska Lidia , Sarnacka Emilia , Waszkiewicz Michał
Published: August 2023

The article consists of three parts showing the changes that took place in the health care law in 2021. The main goal was to discuss those legislative changes that, according to the authors, are innovative and in the future will have a significant impact on the shape of the entire health care system in Poland.
PENGARUH KOMPONEN ARUS KAS DAN LABA KOTOR TERHADAP HARGA SAHAM
Authors: Doloksaribu Ardin , Tambunan Bonifasius , Rambe Meysin
Published: August 2023

Laporan keuangan merupakan sarana yang penting bagi investor dan kreditur untuk mengetahui perkembangan perusahaan secara periodik karena laporan keuangan merupakan sumber informasi yang sangat penting dan dibutuhkan oleh pemakai laporan keuangan. Investor dan kreditur menggunakan informasi arus kas sebagai ukuran kinerja perusahaan, karena informasi tentang arus kas digunakan sebagai dasar untuk menilai kemampuan perusahaan dalam menghasilkan kas dan setara kas serta menilai kebutuhan perusahaan untuk menggunakan arus kas tersebut. Selain arus kas, parameter kinerja perusahaan yang menjadi perhatian utama adalah laba, pada penelitian ini berfokus pada laba kotor karena laba kotor lebih dapat menggambarkan hubungan antara laba dengan harga saham.

Penelitian ini bertujuan untuk menguji secara empiris pengaruh komponen arus kas (aktivitas operasi, aktivitas investasi, aktivitas pendanaan) dan laba kotor terhadap harga saham. Penelitian ini menggunakan metode penelitian regresi berganda dengan sampel sebanyak 45 perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia dari tahun 2018 – 2020. Alat analisis yang digunakan adalah program SPSS versi 26.   

Hasil yang didapat dalam penelitian ini adalah bahwa secara simultan variabel aktivitas operasi, aktivitas investasi, aktivitas pendanaan, dan laba kotor berpengaruh signifikan terhadap harga saham. Secara parsial hanya variabel aktivitas pendanaan yang berpengaruh signifikan terhadap harga saham.
CONSTRUÇÃO DE UM GUIA EDUCATIVO SOBRE PREVENÇÃO DE CÂNCER DE PRÓSTATA
Authors: Silva Dayane Cereja Ferreira da , Machado Angélica Homobono , Lima João Paulo Menezes , Dias George Alberto da Silva , Dias Biatriz Araújo Cardoso
Published: August 2023

O presente estudo tem como objetivo construir uma tecnologia educacional sobre prevenção de câncer de próstata. Esse estudo foi uma pesquisa metodológica com base três fases: diagnóstico situacional, revisão bibliográfica e construção da tecnologia. O diagnóstico situacional foi oriundo da vivência como discente observada na prática curricular, a revisão bibliográfica admitiu artigos científicos primários com a seleção dos seguintes descritores em português: Neoplasias da Próstata; Atenção Primária à Saúde; Tecnologia Educacional e em inglês: Prostatic Neoplasms; Primary Health Care; Educational Technology, no período de 2017 a 2022 nas bases de dados utilizadas foram: PubMed, Scientific Electronic Library Online (SciELO) e Biblioteca Virtual em Saúde (BVS). Foram selecionados 6 artigos que permitiram a seleção dos pontos a serem abordados, estes foram desenvolvidos e organizados para a construção da tecnologia educacional no formato de guia educativo utilizando linguagem acessível e esquemática, com caráter ilustrativo para facilitar o entendimento e compreensão do público-alvo. A parte estrutural do constructo foi realizada no Programa Software CANVA. A versão final do guia educativo denominado de “Tatá e os cuidados com a saúde do homem” apresenta 24 páginas, incluindo a capa, contracapa, apresentação, sumário, 11 capítulos com tópicos principais, referências consultadas e o caça palavras. Conclui-se, dessa forma, a importância do guia educativo, haja vista a construção e consolidação do conhecimento acerca do câncer de próstata, tornando o homem consciente e protagonista do cuidado com a saúde, ao evitar fatores de risco modificáveis e buscar melhora da qualidade de vida.
PELATIHAN PENGOLAHAN LIMBAH BAGLOG JAMUR TIRAM MENJADI BRIKET DI KECAMATAN PAJARAKAN KABUPATEN PROBOLINGGO
Authors: Lidyana Novita , Perwirasari Dyah Ayu , Haidiputri Trivosa AN , Rustianawati Mutimmah , Junaidi Junaidi
Published: August 2023

Baglog merupakan media tanam yang digunakan oleh petani dalam membudidayakan jamur tiram. Baglog yang telah habis masa produktifnya pada umur empat bulan, akan menjadi masalah bagi petani. Baglog tersebut berubah menjadi limbah padat yang nantinya akan terbuang secara sia-sia serta mengotori dan mencemari lingkungan setempat. Untuk itu perlu adanya pemrosesan menjadi sesuatu yang lebih bermanfaat serta memiliki nilai ekonomis yakni dengan pembuatan briket yang berasal dari limbah baglog. Melalui pengabdian masyarakat oleh Dosen Universitas Panca Marga Probolinggo mengajak kelompok tani “Arka Jamur” di Kecamatan Pajarakan Kabupaten Probolinggo dengan mengadakan Pelatihan Pengolahan Baglog Jamur Tiram Menjadi Briket. Tujuan pelatihan ini adalah mengurangi limbah baglog, dan pembudidaya pada kelompok petani “Arka Jamur” memiliki kemandirian serta keterampiran dalam memproduksi briket dari baglog jamur yang berkualitas serta dapat dijual untuk menambah pendapatan petani
INOVASI PAKAN ORGANIK LIMBAH AMPAS TAHU SEBAGAI SOLUSI PENINGKATAN PROFIT DAN PRODUKSI PADA KELOMPOK TERNAK LELE DI DESA KAPONGAN KABUPATEN SITUBONDO
Authors: Rahman Lula Daihuda Nurur , Prahara Dwi Gita Dian , Aulia Syifa , Puryantoro Puryantoro , Arief Mohammad Yahya
Published: August 2023

Lele merupakan salah satu ikan hasil perairan tawar yang banyak diminati oleh masyarakat Situbondo. Di Desa Kapongan, terdapat 5 peternak lele yang membudidayakan lele sejak 2016 dan tergabung dalam Kelompok Ternak Lele Jaya Mandiri. Potensi kelompok ternak ini sangat potensial untuk terus dikembangkan karena banyaknya pasar dan konsumen peminat ikan lele. Sementara Kelompok Ternak Lele Jaya Mandiri tidak dapat meningkatkan kuantitasnya karena terkendala dengan tingginya pakan yang harus disiapkan. Kelompok ternak lele ini mengalami permasalahan yang tidak jauh berbeda seperti kelompok ternak lainnya, yaitu tingginya harga pakan lele. Biaya pengadaan pakan ikan merupakan komponen terbesar yang dapat mencapai ± 60% dari total biaya produksi. Harga pakan yang tinggi merupakan permasalahan utama yang dihadapi pembudidaya ikan lele. Maka dari itu diperlukan pakan alternatif yang berasal dari alam. Salah satu alternatif yang dapat digunakan adalah ampas tahu. Desa Kapongan juga sebagai salah satu desa sentra industri tahu di Situbondo. Terdapat 16 UKM industri tahu dengan kapasitas produksi menengah ke atas. Perusahaan tahu ini menghasilkan limbah ampas tahu kurang lebih 30 kg/harinya. Hal ini sangat mengganggu lingkungan, dan hanya dimanfaatkan sebagai pakan ternak dan tidak terserap sepenuhnya. Penggunaan ampas tahu sebagai alternatif pakan menjadi sebuah solusi untuk meningkatkan profit dan produksi sekaligus sebagai upaya penyelamatan lingkungan.
PEMANFAATAN APLIKASI KINEMASTER UNTUK ALAT BANTU PEMBUATAN VIDEO DALAM RANGKA MENINGKATKAN LITERASI TEKNOLOGI INFORMASI
Authors: Cahyanto Triawan , Fitriyah Nur Qadariyah , Fadhilah Alvi Nur , Munawaroh Sulistyowati
Published: August 2023

Mayoritas lapisan masyarakat saat ini sudah memiliki gawai yang mumpuni untuk mendukung segala aktivitas sehari-hari. Hal ini tentu saja menjadi suatu keunggulan tersendiri yang dapat dimanfaatkan untuk menciptakan hal-hal yang positif sehingga dapat bermanfaat untuk seluruh individu. Literasi teknologi informasi belum semuanya mampu diperoleh masyarakat khususnya dalam hal pembuatan video. Oleh karena itu, pada kegiatan Program Kemitraan Masyarakat Stimulus ini, tim pengusul berupaya untuk memberikan pelatihan pemanfaatan aplikasi kinemaster untuk pembuatan video yang nantinya diharapkan dapat mendukung untuk pembuatan dokumentasi video terkait kegemaran atau hobi para peserta. Hal ini juga selaras dengan kebutuhan dari masyarakat yang menginginkan agar para ibu rumah tangga dapat memiliki aktivitas positif dan produktif. Kegiatan yang dilakukan secara umum terdiri dari tiga tahap, yaitu tahap sosialisasi atau pemaparan materi, tahap praktik pembuatan video dan tahap evaluasi. Setelah seluruh kegiatan berhasil terlaksana, peserta yang hadir pada kegiatan ini mengalami peningkatan pengetahuan terkait dengan pembuatan video dengan aplikasi kinemaster. Selain itu, kemampuan peserta dalam memanfaatkan sosial media juga semakin baik.
TEKNOLOGI TEPAT GUNA PADA PROSES PENYARINGAN SUSU KEDELAI DI INDUSTRI PENGOLAHAN TAHU
Authors: Murdianto Deny , Nurdin Muhammad Firdan , Sudirman Sudirman , Santoso Hadi , Kismanti Shinta Tri , Waluyo Marhadi Budi , Ridwan Rasmawati , Santoso Dwi , Silalahi Prayoga Raja Lambok
Published: August 2023

Industri pengolahan tahu dan tempe Bapak Fandy terletak di Jl. Damai Bakti, Kelurahan Karang Harapan,Kecamatan Tarakan Barat, Kota Tarakan. Dibutuhkan waktu yang cukup lama bagi industri ini untuk dapat menghasilkan produk yang berkualitas dan mampu diterima di pasaran. Proses produksi dan bahan baku yang tepat merupakan dua hal penting yang pada akhirnya membuat tahu dan tempe hasil olahan industri Bapak Fandy ini dapat diterima pasar hingga saat ini. Proses penyaringan adalah proses yang harus dilakukan berulang dengan beban yang harus diayunkan lebih dari 10 kg sekali ayun. Aktivitas penyaringan yang dilakukan menyebabkan keluhan rasa sakit dan pegal-pegal pada bagian tubuh. Selain itu, rasa panas pada tangan dan wajah yang harus berhadapan langsung pada kuali juga menjadi permasalahan saat penyaringan susu kedelai pada proses pembuatan tahu. Alat tepat guna yang dikembangkan dapat mempermudah pekerja dalam proses penyaringan karena telah menggunakan motor listrik sehingga pekerja tidak perlu menanggung beban kerja yang cukup berat, meningkatkan produktivitas perhari, serta menghemat biaya serta meminimasi jumlah tenaga kerja.
PENCEGAHAN STUNTING DENGAN PROMOSI KESEHATAN PADA MASYARAKAT POSYANDU MANGGIS V ARJASA
Authors: Labib Ahmad Shofiyul , Mahardiyanto Agus , Prianto Fajar Wahyu , Wiryaningtyas Dwi Perwitasari
Published: August 2023

Stunting adalah suatu gangguan tumbuh kembang yang dialami oleh anak dikarenakan kurang gizi yang bersifat kronis. Gizi ini paling utama yaitu pada 1000 hari pertama kehidupan. Jember memiliki angka stunting, AKI, dan AKB tertinggi di Jawa Timur. Tujuan dari kegiatan ini adalah untuk menurunkan angka stunting, AKI, dan AKB di Jember melalui tindakan preventif, kuratif dan rehabilitatf. Pendekatan yang dilakukan dalam kegiatan pengabdian pada masyarakat wilayah kerja posyandu Mangga V adalah promosi kesehatan mengenai KMS dan Growth chart WHO, pentingnya ASI ekslusif, tantangan pemberian ASI ekslusif, penolongan pertama saat terjadi tantangan menyusui ASI ekslusif, dan juga gaya hidup sehat pada ibu hamil. Hasil dari kegiatan ini diharapkan masyarakat memiliki kebiasaan pola hidup sehat. Kebiasaan pola hidup sehat yang dimiliki masyarakat ini bertujuan untuk menekan angka kejadian stunting, AKI, dan AKB di wilayah kerja Posyandu Manggis V Dusun Krajan, Desa Arjasa, Kecamatan Arjasa, Kabupaten Jember.
PENINGKATAN KETERAMPILAN PETERNAK SAPI PERAH DALAM PENGOLAHAN PAKAN HIJAUAN DI DESA BALUNG LOR KECAMATAN BALUNG KABUPATEN JEMBER
Authors: Malika Uyun Erma , Prasetyo Anang Febri , Wijaya Jemi Cahya Adi
Published: August 2023

Kebutuhan pakan hijauan untuk sapi perah sangat tinggi sebagai asupan makanan atau energi agar dapat menghasilkan susu perah yang berkuantitas dan berkualitas tinggi. Ketersediaan hijauan tersebut akan semakin berkurang pada saat musim kemarau tiba, seperti yang terdapat pada peternak sapi perah di Kabupaten Jember yaitu kelompok ternak “Mandiri Sejahtera” yang terdapat di Desa Balung Lor Kecamatan Balung Kabupaten Jember. Berkaitan dengan permasalahan dan analisis situasi di sekitar lokasi para peternak tersebut, maka dalam kegiatan ini akan diberikan solusi berupa teknik pengolahan pakan melalui pemanfaatan bahan baku limbah jerami kedelai yang banyak terdapat di sekitar lokasi peternak sebagai alternatif sumber pakan hijauan sapi perah. Metode pendekatan yang dilaksanakan dalam pelatihan ini adalah melalui pendekatan on farm. Pelaksanaannya memperhatikan konsep efisiensi dan efektifitas penggunaan sumberdaya lokal dan peningkatan sumberdaya manusia (human resource), yaitu melalui pelatihan pengolahan jerami kedelai sehingga dapat digunakan sebagai alternatif sumber pakan hijauan sapi perah. Berdasarkan hasil kegiatan maka target dan luaran dapat tercapai, yaitu berupa peningkatan keterampilan peternak sapi perah khususnya pada kelompok ternak “Mandiri Sejahtera” dalam  hal pengolahan jerami kedelai menjadi alternatif sumber pakan hijauan (hay) untuk memenuhi kebutuhan pakan sapi perah.
PENANAMAN MANGROVE SEBAGAI UPAYA PENCEGAHAN ABRASI DI DESA PABEAN KECAMATAN DRINGU KABUPATEN PROBOLINGGO
Authors: Tyas Yayuk I.W , Koeshardjono R. Hery , Yatiningrum Agung , Amani Tatik , Rahajeng Yekti , Putri Wahyu Musafikah , Wijaya Widya Febryanti , Nirbaya Nanda P.A , Hasanah Apriliatul
Published: August 2023

Ekosistem hutan mangrove merupakan habitat penting bagi organisme kelautan dan sebagai penjaga pantai dari abrasi. Salah satu daerah yang mempunyai hutan mangrove dan cukup rentan dengan terjadinya abrasi adalah Desa Pabean - Dringu di Kabupaten Probolinggo. Kegiatan ini bertujuan untuk meningkatkan kesadaran masayarakat tentang pentingnya mangrove dalam mencegah terjadi abrasi, khusunya di Desa Pabean - Dringu. Kegiatan ini melibatkan warga Desa. Secara umum, kegiatan ini berjalan dengan lancar dan diikuti dengan antusias yang cukup tinggi oleh seluruh peserta.  Metode dilakukan dengan cara penyuluhan dan  penanaman.Diharapkan dengan adanya kegiatan ini, masyarakat Pabean Kecamatan Dringu dapat memahami dan mengambil manfaat besar yang dimiliki oleh mangrove serta mencegah Desa Pabean - Dringu dari abrasi.
EDUKASI KESEHATAN REPRODUKSI DAN SEKSUAL DI KELURAHAN KARANGPOH KECAMATAN GRESIK KABUPATEN GRESIK JAWA TIMUR
Authors: Hamidah Siti , Rizal Muhammad Saiful
Published: August 2023

Semua ibu pasti mendambakan memiliki putra / putri dengan fisik yang sempurna, sehat, dan cerdas. Selanjutnya setelah dewasa memiliki kemampuan yang mumpuni dan sukses. Tentunya hal ini tidak terjadi begitu saja, namun diawali dengan persiapan saat sebelum hamil, selain itu Yang Maha Kuasa yang menentukan nasib seseorang melalui upaya manusia itu sendiri. Setiap orang memiliki hak dalam mengatur hak reproduksinya, yaitu; memiliki hak yang sama dalam memutuskan kapan akan memiliki anak, jumlah anak berapa, mendapatkan informasi yang lengkap tentang kesehatan reproduksi dan seksual. Untuk mendapatkan anak yang sehat, cerdas, dan berkualitas terlebih dahulu perlu dipersiapkan sejak pranikah. Tujuan dari pengabdian masyarakat ini adalah; (1) Memberikan pengetahuan tentang kesehatan reproduksi dan seksual, (2) Memberikan pengetahuan tentang persiapan pranikah. (3) Mendapatkan keturunan yang sehat fisik, sehat secara psikologis, cerdas dan berkualitas. Berdasarkan hasil evaluasi, peserta dapat menjawab kuesioner setelah pelaksanaan workshop dengan hasil yang sangat baik sebesar 60% dan hasil yang baik sebesar 40%. Pengabdian masyarakat dilaksanakan melalui workshop yang diikuti oleh warga PKK Kelurahan Karangpoh, Kecamatan Gresik, Jawa Timur.
Distinct behavioral effects of short-term voluntary running in phosphatase and tensin homolog deleted on chromosome 10 neuronal haploinsufficient mice
Authors: Andreotti Diana Zukas , de Mello Natália Prudente , Paixão Amanda Galvão , Scavone Cristoforo , Orellana Ana Maria , Kawamoto Elisa Mitiko
Published: August 2023

Phosphatase and tensin homolog deleted on chromosome ten (PTEN) is a tumor suppressor with functions related to its phosphatase activity. PTEN plays various roles, such as cell proliferation, survival, and migration and is involved in neurogenesis and synaptic plasticity in the central nervous system. It has been reported that running could have protective effects against the aging process and neurodegenerative diseases. Therefore, we aimed to evaluate the effects of physical exercise on behavioral and biochemical aspects of PTEN-conditioned knockout female mice. We observed that 10 days of voluntary running positively affected fear memory but caused no changes in anxiety-like behavior. However, it was unable to counteract the social recognition memory deficit in PTEN neuronal haploinsufficient mice. In terms of biochemical aspects, we observed that short-term running reduced S6 phosphorylation in PTEN heterozygous mice and PTEN protein expression independent of the genotype. In addition, PTEN heterozygous mice presented reduced N-methyl-D-aspartate subunit NR1 protein expression. Our results regarding decreased S6 phosphorylation in HT mice suggest that short-term voluntary running could have induced a protective effect in reducing dysregulated cell growth, possibly related to the downregulation of tumor suppressor expression/activity such as PTEN. Moreover, running induced distinct behavioral effects in PTEN-conditioned knockout mice.
Invasion of Endophytic Bacteria by Using Microencapsulation Technology as Stimulant in Cocoa Plants (Theobroma cacao L)
Authors: Prayoga Gusti Yanda , Warsito Kabul , Amrul Hanifah Mutia Z.N.
Published: August 2023

Fertilization is an important process in the growth of cocoa (Theobroma cacao L). Fertilizing cocoa usually used inorganic fertilizers. Using of inorganic fertilizers continuously could degrading soil fertility. One of the efforts to replace inorganic fertilizers was using endophytic bacteria as biofertilizers. Some endophytic bacteria are abundant in healthy plant tissues. The aim of this research was to obtain endophytic auxin-producing bacteria in cocoa plants and determine the effect of seed immersion and microcapsules addition of endophytic bacteria on cocoa plant growth. The research design used was Complete Randomized Design (CRD), 16 treatments and 3 replications. The first factor was immersion of cocoa seed using endophytic bacteria suspension consisting of S0= 0 hours; S1= 5 hours; S2= 6 hours and S3= 7 hours and the second factor was microcapsules addition consisting of B0= 0 gr; B1= 5 gr; B2= 10 gr; B3= 15 gr. Isolation from the roots and stems of cocoa obtained 5 isolates endophyte bacteria. Auxin assays showed that five isolates were able to produce auxin. Observations on plant height showed the best treatment was treatment B1 (32.49 cm). Observation of total leaves showed S3 treatment was the highest data (11.83 strands). Observation rod diameter parameter, highest data was S3 treatment (4.01 mm). For leaf area parameter, highest value was B1 treatment (66.64 cm2). For wet weight parameter, highest data was S3 treatment (18.41 g). Root length parameter, highest data was B3 treatment (15.78 cm).  Test results showed that the application of suspension and microcapsules of endophytic bacteria significantly increased growth of cocoa.
The Diversity of Reptile Species in Mangrove Ecotourism of Kampung Rawa Mekar Jaya, Siak Regency
Authors: Putra Aldi Ardiansyah , Yoza Defri , Setyawatiningsih Sri Catur
Published: August 2023

Rawa Mekar Jaya mangrove ecotourism is the last mangrove forest on the east coast of Sumatra Island. This mangrove forest is a home for reptiles. The reptilian fauna of the Mekar Jaya mangrove has the potential to become an ecotourism object. This study aims to determine the diversity, evenness, abundance, and status of reptile species in the Mekar Jaya mangrove ecotourism. Four 3 x 400 m transects were conducted in two habitat types: aquatic (10 m of bank) and terrestrial (30 m of bank). Observations were made in the morning and evening at low tide and repeated five times at three-day intervals. Direct collection of reptile data using a visual survey (VES) and passive sampling (glue trap). The researchers managed to capture 52 individuals, which were reptiles, consisting of 4 species (Draco sumatranus, Hemidactylus platyurus, Mabuya multifasciata, and Varanus savator) found directly in the field. The results of the interviews with the managers indicate that there are 2 species of crocodiles: Crocodylus porosus and Tomistoma schlegelii. Shannon-Wiener diversity index value was medium (H'=1.02). Evenness index was labile (0.57). The highest species abundance was M. multifasciata (0.65), while the lowest abundance was H. platyurus (0.12). All reptile species found were not protected. V. salvator is classified as a low-risk species (LC/Minor Concern) and is listed in Appendix II of CITES. Two crocodile species reported by the community are protected. T. schlegelii is vulnerable and listed in Appendix I of CITES. C. porosus is low-risk and listed in CITES Appendix II.
Bioactive Contents, BSLT Toxicity and antioxidants from Apis dorsata Binghami and Apis mellifera nest extracts
Authors: Tuegeh Reinny Silvana , Sumampouw Herry Maurits , Tanor Meity Neltje , Mokosuli Yermia Semuel
Published: August 2023

Beenest is rich in secondary metabolites because honeycombs, among others, are formed from plant resins (propolis). This study aimed to analyze differences in flavonoid content and in vitro antioxidant activity of Apis dorsata Binghami and Apis mellifera nest extracts. The samples used were A. dorsata from North Sulawesi and A. mellifera from South Sulawesi. The honeycomb was extracted using 95% ethanol solvent. Honeycomb extract was analyzed for its flavonoid content by the HPLC method, toxicity was tested by the BSLT method, and in vitro antioxidant activity was tested by the DPPH method. The results of the analysis of flavonoids showed that A. dorsata nest extract produced 21 types of compounds while A. mellifera produced 26 types of compounds. The toxicity test results showed that the A. dorsata nest extract had a better LC50 of 245,691 mg/l than the A. mellifera nest extract with an LC50 of 443,701 mg/l. The in vitro antioxidant test results of A. dorsata nest extract were more robust, namely IC 50 1.161 mg/l, compared to A. mellifera nest extract IC 50 2.404 mg/l. However, both were included in the category of powerful antioxidants. In vitro, anticancer test results on MCF-7 cells, A. mellifera nest extract was active with IC 50 100.02mg/l. Compared to A. dorsata extract, it was active with IC 50 102.217mg/l, but the two were not significantly different. Based on the analysis of flavonoid content, toxicity test, and antioxidant test, A.dorsata and A.mellifera honeycomb extracts have potential as in vitro antioxidants
Politology
Authors:   Open International University of Human Developmеnt «Ukraine», Lisovskiy Petro , Lisovska Yulia ,   Interregional Academy of Personnel Management: Kiev
Published: August 2023

The guide reveals the actual problems of each section of the "Politology" course. A conceptual framework is presented in which the basic categories in the system of political science knowledge are defined. In the structural organization of political science, the main tools for creating a political brand, as well as recruiting the political elite, are considered. The conceptual model of reforming interdepartmental power structures in political science is defined. The post-Covid syndrome and countermeasures, as well as the security situation in the East of Ukraine, are highlighted in international practices of political science. The issue of the phenomenon of freemasonry as a hidden phenomenon in world leadership is raised. The educational and scientific manual is intended for scientists, teachers, students, cadets, as well as employees of special services.
THEORY OF INTERNATIONAL RELATIONS
Authors:   Open International University of Human Developmеnt «Ukraine», Lisovskiy Petro , Lisovska Yulia ,   Interregional Academy of Personnel Management: Kiev
Published: August 2023

In the textbook, the authors highlight the philosophical-historical process of the wisdom of the peoples of the world as a hypothetical picture of the quality of the reinterpretation of the individual, the state, and society in the theory of international relations. Attention is focused on the method of quantum computerization as a phenomenal digital communication in the international legal field. It is predicted that under the conditions of the international post-covid syndrome, quantum vaccination occupies a significant place in the hierarchical nature of the crystalline structure of the universe. This will contribute to a qualitatively new cycle of wise decisions among the peoples of the world. The manual is designed for teachers, students and anyone interested in international relations.
Caça: Subsídios para Gestão de Unidades de Conservação e Manejo de Espécies
Authors: Brasileira Biodiversidade
Published: August 2023

Em 2018, os números 1 e 2 da revista tratam da questão da caça, buscando subsídios para a gestão de unidades de cosnervação e manejo de espécies, e o editorial publicado no segundo número contempla os artigos de ambos. Link: http://www.icmbio.gov.br/revistaeletronica/index.php/BioBR/article/view/1425
Identifying High-Risk Individuals for Suicide During Covid-19 Pandemic: Prevention and Intervention
Authors: Aslam Naeem , Malik Jamil A. , Khan Maryam
Published: August 2023

Background. The mental health outcomes of the coronavirus pandemic (COVID-19) might be hazardous and may evoke a tsunami of mental illness. Multiple lines of evidence indicate that the COVID-19 pandemic has profound psychological and social effects. It has been expected that the mental illnesses and suicide rates may rise not only due to the suffering of the pandemic itself but also to prolonged combat strategies, including lockdown and quarantine over a longer period. It is henceforth important to identify potential risk factors for developing risk prevention strategies with urgent consideration.Materials and Methods. A systematic review approach was employed to collect information regarding the high-risk individuals for suicide during a pandemic and subsequently present the prevention and intervention-focused strategies for managing the condition. The article published just after the pandemic outbreak including the time period: 2019 to 2020 available at PubMed, PsycINFO, and LISTA, was considered for the present study.Results. The findings suggest that the COVID-19 pandemic is associated with solitude, agony, anxiety, fear of infection, depression, insomnia, and economic complications. These conditions may subsequently lead to complex psychiatric complaints in vulnerable populations, including individuals with pre-existing psychiatric disorders, those having a history of suicide attempts, and those taking treatment for suicide risk.Conclusion. To decrease the risk of suicides during COVID-19, reducing people's stress, anxiety, and loneliness is important.  Specialized training in the workforce on crisis management would have additional benefits. Governments shall devote adequate funding and resources to control the mental health consequences of the pandemic.
Comparison Between the Combination Therapy in Terms of Therapeutic Effectiveness and Anti-Microbial Efficacy in Extensive Drug-Resistant Acinetobacter Baumannii Infections
Authors: Parveen Naila , Sikander Rana Imran , Zeeshan Muhammad , Muneeb Ali Syed , Hassan Muhammad
Published: August 2023

Objective: To compare the clinical and antimicrobial efficacy of a triple-antibiotic regimen (Colistin, Cefoperazone/Sulbactam, and Tigecycline) with a double-antibiotic regimen (Colistin and Minocycline) for treating drug-resistant Acinetobacter baumannii infections in critically ill patients.Study Design:  A comparative cross-sectional study design.Place and Duration of Study: The study was conducted at the Medical Intensive Care Unit (ICU) of Pakistan Institute of Medical Sciences (PIMS), Islamabad, Pakistan from April 2022 to October 2022.Materials and Methods: A total of 38 patients aged 18-70 years admitted to the Medical Intensive Care Unit (ICU) of the Pakistan Institute of Medical Sciences, Islamabad gave consent to participate in the study. Any patient having a culture-proven polymicrobial infection was excluded. A total of 20 patients were allocated to Group A (triple-antibiotic regimen) and 18 patients to Group B (double-antibiotic regimen). Vital statistics were recorded daily, while laboratory-based biochemical markers (leucocyte count, CRP, lactate, procalcitonin) were recorded every 48 hours for ten days. Antimicrobial efficacy was assessed by a culture analysis on the 10th day.Results: There were 20 patients in Group A and 18 in Group B. There were 32 patients with Ventilator-Associated Pneumonia (VAP), and six with bloodstream infection. No significant difference in the vitals and lab markers were found between the two groups. The only exception was serum lactate levels, which were significantly higher Group A (34.03 + 28.37 mg/dL), compared to Group B (16.11 + 15.63 mg/dL; p = 0.024). Group A therapy was also found to have significantly improved antimicrobial efficacy in terms of positive-culture results (n=4, 20%) compared to Group B (n=10, 55.6%; p = 0.023).Conclusion: The triple-antibiotic regimen had better antimicrobial efficacy than the double-antibiotic regimen for treating Acinetobacter baumannii-related infections.
Prevalence of Mediterranean Mutation of Glucose 6 Phosphate Dehydrogenase in Children of Malak Din Khel Subtribe of Afridi
Authors: Amjid Mohammad , Farooq Nazish
Published: August 2023

Objective: To determine the prevalence of Glucose 6 Phosphate Dehydrogenase (G6PD) deficiency in the Malak Din Khel subtribe, the biggest subtribe of Afridi, with expectations of newer findings in the area of medicine and research.Study Design: Cross-sectional study.Place and Duration of Study: This study was conducted in District Khyber from March 2018 to August 2018.Materials and Methods: The sample size of this study was 177 preschool-going children of 4-5 years of age. Multistage cluster sampling was done. Only resident families of Khyber Agency were selected. Children of age 04 to 05 years were enrolled in the study after consent from a parent/ guardian. Children with major comorbidities, non-consenting parents/ guardians, and children transfused in the last 24-48 hours were excluded from the study. 05 ml of blood was collected from each child. G6PD qualitative tests were performed in the field; rest of the tests were carried out later at Dabgari Garden “”in lab. PCR was processed according to protocol. Data were analyzed by SPSS 26.0.Results:  A total sample size of 177 respondents were initially investigated through a qualitative test for G6PD deficiency. Among these, only 4 (2.3%) respondents were found to be G6PD deficient, The PCR analysis depicted that among 177 respondents, 31 (17.5%) were found to be mutant. Among these, 26(84%) were heterozygous, while 5 (16%) respondents were found to be homozygous. The PCR analysis further revealed that among the 5 homozygous respondents, 3 were found to be G6PD deficient, as also depicted by the qualitative test. One of the homozygous respondents, although found deficient by qualitative test, showed no Mediterranean mutation.Conclusion: Most studies done in Pakistan are hospital-based and the method for diagnosing is a qualitative test, but if the G6PD enzyme activity level is more than 30% qualitative test cannot pick the respondent as deficient. In our study, we ran qualitative tests on all respondents and only 4/177(2.3%), followed by PCR analysis for Mediterranean mutation of all samples, which showed that 31/177 (17.5%) were G6PD deficient. Further studies need to be conducted in the same manner to know the exact prevalence of G6PD. Detailed studies in other ethnic groups of the country must also be conducted to highlight the actual position of this threat.
Rovatszerkesztői bevezető – Didaktika napjainkban
Authors: Fűzi Beatrix , Horváth László
Published: August 2023

Az elmúlt évben Falus Iván főszerkesztésében és Szűcs Ida szerkesztésében megjelent a Didaktika kézikönyve, amely a tanítás tudományáról a mai igények szerint szól. A Didaktika c. könyv előző kiadása óta eltelt csaknem húsz esztendő jelentős változásokat hozott az oktatás területén, többek között ilyen a digitalizáció, a súlyosbodó pedagógushiány, a tanárképzés és a tanárjelöltek iskolai gyakorlatainak rendszeres átalakítása. A könyv megjelenése jó alkalom arra, hogy átgondoljuk a didaktika jelentőségét, alkalmazását napjainkban. Jelen lapszámunkkal sorozatot indítunk, hogy ezt különböző nézőpontokból megvizsgáljuk. Szerzőink foglalkoznak majd a didaktikai szempontok érvényesülésével digitalizált oktatási környezetben, a tanulás- és tanításértelmezések tanárképzésben betöltött szerepével, továbbá a didaktika iskolai gyakorlatokkal és szakmódszertanokkal való kapcsolatával. Sorozatunk első szerzője azzal foglalkozik, hogy a didaktika alapkérdéseire – mit, hogyan, hol és ki tanítson? – milyen válaszok adhatók a tanárhiánnyal sújtott, új hardver- és szoftverkörnyezetben. Várjuk Olvasóink véleményét, reflexióit az írásokra és a felvetett kérdésekre!
Optimal Portfolio Analysis with Solver Application in Wetland Plantation Subsector
Authors: Sadikin Ali , Fahmi Roy Dalimunthe  , Nadia Zulfati Fairuz  , Dina Nugraheni
Published: August 2023

Investments made by investors should submit to a Markowitz portfolio, where the goal is to get an optimal portfolio investment from several existing stocks. The goal of a portfolio is to maximize stock returns and minimize risk. The object of this study is plantation sub-sector companies listed on the IDX for the 2018-2022 period. The population is 19 companies in the plantation sub-sector, while the sampling method is 6 companies using purposive sampling. Through this research, investors are expected to be able to see which stock portfolio is the most optimal of several efficient portfolios in the agricultural sector. In addition, the plantation sub-sector supports government programs on food security for industry and consumers and increases non-oil and gas income, and increases the income of all relevant stakeholders, which in turn can increase the income and welfare of the Indonesian people.
Current Overview of Scientific Production Associated with Governance in University: A Bibliometric Analysis
Authors: Martínez Edgar German , Sánchez Vázquez Elizabeth , Poveda Aguja Fernando Augusto , Barbosa Guerrero Lugo Manuel , Cruz Mican Edgar Olmedo
Published: August 2023

The main objective of this research is to identify the current panorama of scientific production associated with governance in university institutions. A bibliometric analysis was developed in Scopus using R Core Team 2022-Bibliometrix and Vosviewer software. The results highlight the countries with the highest productivity in the topic of study, with the most representative authors favoring the understanding of governance. The main thematic clusters stand out. It recognizes the role of university governance and its migration to direct spaces and the transition from a face-to-face model.
Perspective of Governance in University Institutions in Virtual Digital Environments
Authors: Martínez Edgar German , Sánchez Vázquez Elizabeth , Poveda Aguja Fernando Augusto , Barbosa Guerrero Lugo Manuel , Cruz Mican Edgar Olmedo
Published: August 2023

Study was born in the construction of problem concepts in the deployment of a governance strategy in institutions under digital environments, a technical position of understanding from South America is raised, the initial hypothesis of knowing aspects and determining requirements, an efficient model of governance can be achieved from the use and application of ICT , which allow to argue the as of the process, The use ICT, TAC, TEP as change managers in virtuality, to interact in a disruptive way, the most important achievements of research to recognize the legal, digital and technological resource environment.
Bioenergetic alteration in gastrointestinal cancers: The good, the bad and the ugly
Authors: Chu Yu-De , Chen Chun-Wei , Lai Ming-Wei , Lim Siew-Na , Lin Wey-Ran
Published: August 2023

Tumor necrosis factor-α (TNF-α) antagonists, the first biologics approved for treating patients with inflammatory bowel disease (IBD), are effective for the induction and maintenance of remission and significantly improving prognosis. However, up to one-third of treated patients show primary nonresponse (PNR) to anti-TNF-α therapies, and 23%-50% of IBD patients experience loss of response (LOR) to these biologics during subsequent treatment. There is still no recognized predictor for evaluating the efficacy of anti-TNF drugs. This review summarizes the existing predictors of PNR and LOR to anti-TNF in IBD patients. Most predictors remain controversial, and only previous surgical history, disease manifestations, drug concentrations, antidrug antibodies, serum albumin, some biologic markers, and some genetic markers may be potentially predictive. In addition, we also discuss the next steps of treatment for patients with PNR or LOR to TNF antagonists. Therapeutic drug monitoring plays an important role in treatment selection. Dose escalation, combination therapy, switching to a different anti-TNF drug, or switching to a biologic with a different mechanism of action can be selected based on the concentration of the drug and/or antidrug antibodies.
Comparison of modified gunsight suture technique and traditional interrupted suture in enterostomy closure
Authors: Chen Chang , Zhang Xiang , Cheng Zhi-Qiang , Zhang Bin-Bin , Li Xin , Wang Ke-Xin , Dai Yong , Wang Yan-Lei
Published: August 2023

Tumor necrosis factor-α (TNF-α) antagonists, the first biologics approved for treating patients with inflammatory bowel disease (IBD), are effective for the induction and maintenance of remission and significantly improving prognosis. However, up to one-third of treated patients show primary nonresponse (PNR) to anti-TNF-α therapies, and 23%-50% of IBD patients experience loss of response (LOR) to these biologics during subsequent treatment. There is still no recognized predictor for evaluating the efficacy of anti-TNF drugs. This review summarizes the existing predictors of PNR and LOR to anti-TNF in IBD patients. Most predictors remain controversial, and only previous surgical history, disease manifestations, drug concentrations, antidrug antibodies, serum albumin, some biologic markers, and some genetic markers may be potentially predictive. In addition, we also discuss the next steps of treatment for patients with PNR or LOR to TNF antagonists. Therapeutic drug monitoring plays an important role in treatment selection. Dose escalation, combination therapy, switching to a different anti-TNF drug, or switching to a biologic with a different mechanism of action can be selected based on the concentration of the drug and/or antidrug antibodies.
Marinduque Island: Where Culture and Adventure Meet for Sustainable Tourism
Authors: Mendoza Lynle N.
Published: August 2023

Marinduque Island is a unique destination that offers a combination of cultural experiences and adventure tourism. To assess the determinants of customer behavior in Marinduque Island, a survey was conducted, and the results were presented in three tables: Summary of Mean for Cultural Experiences, Summary of Mean Ratings for New Environment, and Summary of Mean Ratings for Adventure. The findings of the study indicate that tourists highly value cultural experiences, unique environments, and exciting adventures in Marinduque Island. Specifically, tourists agreed that the creation of natural learning experiences, cultural interactions, and pleasing cultural experiences are important factors that reinforce their intent to return to Marinduque Island. They also agreed that the new tourism destination provides a unique physical environment that encourages return visits and destination loyalty. Moreover, tourists perceived that physical environment changes and unique experiences in Marinduque Island promote exciting experiences in adventure tourism. This suggests that adventure tourism in Marinduque Island is an important factor that contributes to the growth and sustainability of the tourism industry in the area. Based on the results, the study recommends that Marinduque Island should focus on providing tourists with unique and memorable experiences, including cultural experiences, a distinct physical environment, and exciting adventures. The recommendations emphasize the importance of encouraging return visits, promoting destination loyalty, and contributing to the growth and sustainability of the tourism industry in Marinduque Island. In conclusion, Marinduque Island is a valuable destination for cultural experiences and adventure tourism, and the findings of the study provide insights for the development of sustainable tourism programs and initiatives in the area.
Religious Importance of Microfinance Bank: A Christian Perspective
Authors: Esther Ojone Joseph
Published: August 2023

In the age of globalisation and increasing global disparity between the rich and poor, the world has seen the rise of a new and celebrated poverty-fighting strategy in the past decades. Microfinance banks provide financial services to poor entrepreneurs, most commonly small loans to help poor individuals start or grow small businesses. Previous studies on microfinance banks have majorly tilted towards its economic, sociological and psychological perspectives with insignificant attention paid to its religious importance. This research work is undertaken to examine the importance of religion to microfinance bank using Christian based microfinance banks as a model for the study. The work was intended to achieve the following objectives: to ascertain the extent to which microfinance bank has impacted the lives of the people that it is targeted towards which is the active poor and to determine the significance of religion to the operations of the bank. The study adopted Max Weber’s theory of religious economy, which hinges on the role of Christianity in the management of economic organisations. The basic research instruments used in this study were oral interview, participatory observation and the use of relevant literatures. The data was properly analysed and discussed. The study observes that microfinance bank has a religious influence based on operations or services on savings, deposit, loans and asset acquisitions. The research identifies the religious importance of the bank which is evident in manifestation of charity, premised on trust, biblical context of usury; it inculcates Christian teachings and inventiveness. However, the study identified some challenges with the bank in which some of the challenges are quite peculiar to the microfinance system of operation. These challenges include; limitation in scope, Central Bank directives, abuse, difficulty in monitoring and competition. Nevertheless, these have in no way reduced the efficiency of the bank in some areas. It is therefore evident that despite the challenges, microfinance bank has contributed immensely to national economic development and this has been achievable due to its religious importance. This work proves beyond measure that religion has not lost its relevance and it’s not only a spiritual reality but a social phenomenon. It is an important tool that helps various economic institutions in the society to function well. The study recommends more of religious teachings inculcated into microfinance banks in order to have a growing and sustainable microfinance industry and also brings to limelight the religious importance of microfinance bank which can serve as a spring board for further researches.