bluuebunny/crossref_metadata_2025 huggingface dataset:
Patient and caregiver perspectives on a tool to identify undiagnosed dementia: A qualitative study
Authors: Palazzo Lorella , Hsu Clarissa , Barnes Deborah , Figueroa-Gray Marlaine , Greenwood-Hickman Mikael Anne , Larson Eric , Dublin Sascha
Published: May 2021

BACKGROUND Early detection of dementia may improve patient care and quality of life, yet as many as half of patients are undiagnosed. Electronic health record (EHR) data could potentially be used to help to identify patients at risk of having undiagnosed dementia who could be targeted for outreach and assessment, but acceptability to patients and caregivers is unknown. METHOD We conducted five focus groups at Kaiser Permanente Washington, an integrated healthcare system in Washington State, to explore feelings about timing of dementia diagnosis, use of EHR-33 based tools to predict risk of undiagnosed dementia, and communication about risk. Two team members analyzed transcripts using inductive thematic coding. RESULTS Participant groups included: patients with dementia or mild cognitive impairment, patients with neither diagnosis, and caregivers. People who were non-white or Hispanic were oversampled. Forty patients and caregivers (63% women; 59% non-white/Hispanic) participated in focus 39 groups. Participants supported early diagnosis, describing benefits such as time to adjust to the disease, plan, involve caregivers, and identify resources. They also acknowledged the possible psychosocial toll of receiving the diagnosis. Participants also supported use of an EHR-based tool, but some worried about accuracy and privacy. Participants emphasized that information about dementia risk should be communicated thoughtfully by a trusted provider and should include advice about prognosis, treatment options and other resources. CONCLUSION Overall, patients and caregivers supported using EHR-based tools to help identify patients at risk of having undiagnosed dementia. Such tools must be implemented carefully to address concerns and ensure patients and caregivers are adequately supported.
Decreased HECTD1 mRNA expression is associated with poor prognosis and enhanced mitochondrial cellular respiratory function in breast cancer
Authors: Uemoto Yasuaki , Katsuta Eriko , Kondo Naoto , Wanifuchi-Endo Yumi , Fujita Takashi , Asano Tomoko , Hisada Tomoka , Terada Mitsuo , Kato Akiko , Okuda Katsuhiro , Sugiura Hiroshi , Kato Hiroyuki , Osaga Satoshi , Takahashi Satoru , Toyama Tatsuya
Published: May 2021

HECT domain E3 ubiquitin ligase 1 (HECTD1) has been reported to be a negative regulator of epithelial-mesenchymal transition and to decrease breast cancer invasion and metastasis. However, the clinical significance and detailed role of HECTD1 in breast cancer remain elusive. We investigated the role of HECTD1 in two large breast cancer cohorts using mRNA and protein expression, and bioinformatics. We examined the prognostic significance of HECTD1 by multivariate analysis. HECTD1 mRNA expression (HECTD1 expression) was lower in breast cancer compared with adjacent normal tissues. HECTD1 expression levels also differed among breast cancer subtypes. Decreased HECTD1 expression was significantly associated with aggressive tumour characteristics, including large tumour size and high histological grade. HECTD1 expression was inversely associated with mitochondrial cellular respiratory function and reactive oxygen species in breast cancer tissues. Multivariate analysis identified low HECTD1 mRNA expression level as an independent risk factor for disease-free (P = 0.009) and overall (P = 0.046) survival among breast cancer patients. There was no association of HECTD1 protein expression with mRNA expression and prognosis. HECTD1 mRNA expression is a candidate prognostic biomarker in breast cancer. The poor prognosis of patients with low HECTD1 mRNA expression may be associated with increased mitochondrial respiratory function.
Microwave sinteringof duplex α/β-SiAlON ceramic cutting inserts: modifying m, n, z values, sintering temperature and excess Y2O3 sintering additive
Authors: Hong Dongbo , Yin Zengbin , Guo Fuzhou , Yuan Juntang
Published: May 2021

Duplex α/β-SiAlON ceramic cutting inserts (30α: 70β) were fabricated by microwave sintering. The effects of solid solution parameters (m, n, z), sintering temperature and amount of excess Y2O3 sintering additive on phase assemblage, microstructure, mechanical properties and cutting performance were investigated. It was found that increasing m value could improve the formation of α phase while high z value over 1.0 would lead to the dissolution of α phase into β phase and intergranular phase. Increasing amount of excess Y2O3 could promote densification and elongated β grain growth, but the excess Y2O3 over 4 wt.% would result in substantial crystallization of M'SS phase thus declining the mechanical properties and wear resistance. The microwave-sintered α/β-SiAlON cutting insert with modified parameters (m = 1.7, n = 1.0, z = 0.7 and 3 wt.% excess Y2O3) was obtained with optimal comprehensive properties, whose tool life was increased by approximately 75% in high-speed milling of Inconel718 superalloy as compared with commercial α/β-SiAlON cutting insert.
Broad lipid phase transitions in mammalian cell membranes measured by Laurdan fluorescence spectroscopy
Authors: Faerber Nicolas , Westerhausen Christoph
Published: May 2021

Employing fluorescence spectroscopy and the membrane-embedded dye Laurdan we experimentally show broad order-disorder-transitions in membranes of various cell lines and red blood cell ghosts. A custom-made setup allows for the determination of fluorescence spectra and the determination of the generalized polarization (GP) as a measure for membrane order in the temperature range of -40°C to +90°C of µl-volumes of cell suspension. While artificial lipid membranes like phosphatidylcholine show sharp transitions as known from calorimetry measurements, living cells in a physiological temperature range do only show linear changes in generalized polarization. However, extending the temperature range shows the existence of broad transitions and their sensitivity to cholesterol content, pH and anaesthetic. Moreover, adaptation to culture conditions like decreased temperature and morphological changes like detachment of adherent cells or dendrite growth are accompanied by changes in membrane order as well. The observed GP changes are equivalent to temperature changes dT in the range of -12K < dT <+6K
System for Prevention and Control of Old Goaf Water during Coal Mine Re-mining
Authors: Dong Shuning , Li Xiaolong , Ma Liuzhu
Published: May 2021

One integrated mine was currently threatened with an old goaf water disaster, therefore, the development of an advanced detection-guarantee system for roadway excavation with no blind area was imperative. Further, multiple geophysical exploration in combination with two types of boreholes were used to explore and drain water technology, with the anomalous geophysical area as the target area, The conventional borehole with the largest water outflow was taken as the target spot, at a low elevation of the mining area, and a remote directional borehole was used to drill into the old goaf along the stable rock strata below the coal seam floor to intercept the dynamic recharge water, which increased the efficiency of roadway excavation 4–9 times. The ‘isolated island’ old goaf water in the mining face was controlled through multiple geophysical exploration combined with the full-coverage exploration technology by conventional boreholes, and the water-rich anomalous area and geological anomalous area were determined, thus ensuring the safety of the mining face in terms of old goaf water. The technology for advanced short-distance exploration, advanced estimate, roadway exploration, and dynamic old goaf water with drainage was used to comprehensively guarantee real-time, safe mining. This system for the prevention and control of old goaf water was applied to a control project for the old goaf water disaster in the 101 mining face. At present, 1.37 Mt of coal has been safely mined from this mining face. The technical system has improved The Detailed Rules for Water Disaster Prevention and Control of Coal Mine (NCMSA 2018), and improved the technology for the prevention and control of old goaf water under conditions where the upper portion in the same coal seam was destroyed by a small-scale coal mine and re-mining.
A Study on the Predictive Maintenance Method of Fully Mechanized Mining Equipment based on Cost and Time Factors
Authors: Cao Xiangang , Xu Tianbo , Zhao Youjun , Zhao Jiangbin , Wang Yan
Published: May 2021

In view of the problems of excessive maintenance and insufficient utilization of equipment service life caused by preventive maintenance of fully mechanized mining equipment with fixed cycle, a predictive maintenance method is proposed. Firstly, based on Weibull distribution function and evolution rules of equipment decay, the evolution model of equipment failure rate is established; Then, the single-objective decision-making models of equipment maintenance cost rate and maintenance downtime rate are established respectively. On this basis, the multi-objective predictive maintenance planning model of fully mechanized mining equipment with comprehensive cost and time factors is established, and the optimal predictive maintenance cycle planning sequence is obtained. Combined with the coal production continuation plan, this paper puts forward a method to determine the optimal maintenance time by making suitable choices between advance maintenance and delay maintenance. The result confirms the effectiveness and superiority of the proposed method.
Development and Validation of LAMP Primer Sets for Rapid Identification of Aspergillus Fumigatus Carrying the cyp51A TR46 Azole Resistance Gene
Authors: Trabasso Plinio , Matsuzawa Tetsuhiro , Arai Teppei , Hagiwara Daisuke , Mikami Yuzuru , Moretti Maria Luiza , Watanabe Akira
Published: May 2021

Infections due to triazole resistant Aspergillus fumigatus are increasingly reported worldwide and are associated with treatment failure and mortality. The principal class of azole resistant isolates is characterized by the presence of tandem repeats of 34 bp or 46 bp within the promoter region of the cyp51A gene. Loop-mediated isothermal amplification (LAMP) is a widely used nucleic acid amplification system which is fast and specific. Here 2 we describe a LAMP assay method to detect the 46 bp tandem repeat insertion in the cyp51A gene promoter region based on novel LAMP primer sets. It also differentiated strains with TR46 tandem repeats from those with TR34 tandem repeats. These results showed this TR46-LAMP method is specific, rapid, and also provides crucial insights to enable development of novel antifungal therapeutic strategies against severe fungal infections due to A. fumigatus with TR46 tandem repeats.
Areca Catechu Leaf Extract-Mediated Synthesis of Stabilized Silver Doped-Copper Oxide Nanoparticles and its Biomedical Applications
Authors: UR Shwetha , Betageri Virupaxappa S. , M.S. Latha , Veerapur Ravindra , Shivamallu Chandan , Kollur Shiva Prasad
Published: May 2021

The current research work gives an insight into the green synthesis of metallic nanoparticle using medicinally important plant, which has gained increasing applications in therapeutics and medicinal science. Herein, we describe an eco-friendly method to synthesize Ag- CuO nanoparticles using Areca catechu leaf extract via solution combustion method. Crystalline structure, size and surface morphology of the synthesized nanoparticles were confirmed by X-ray diffraction (XRD), Scanning Electron Microscopy (SEM), Energy Dispersive Spectroscopy (EDS), Transmission Electron Microscopy (TEM) and Fourier Transformer Infrared Spectroscopy (FTIR). XRD patterns of the as-prepared Ag-CuO NPs revealed that they possess monoclinic crystalline structure. The morphology and the elemental composition was found by SEM-EDS and TEM analysis, which revealed the nano-spherical shape of Ag-CuO NPs. Further, the Ag-CuO NPs were tested for Antidiabetic activity by using Yeast cell model and amalyze inhibition, which showed promising antidiabetic activity. In addition, the as-prepared material displayed significant anticancer activity against MCF-7 cancer cell line.
CoVAM: Complementary and Alternative Medicine Clinical Trials Database for COVID-19 Disease
Authors: Sharma Vishwas , Mann Zoya , Sharma Amitesh , Srivast Avani , Raghav Pawan Kumar , Singh Ritu , Nandan Amrita
Published: May 2021

Since the inception of the COVID-19 pandemic, a large number of clinical trials on complementary and alternative medicine (CAM) for SARS-CoV-2 infection (COVID-19 disease) have been registered. The information is scattered at different resources making it difficult for researchers, scientists, health care professionals, and the general public to remain up-to-date on the latest CAM clinical trials being registered for COVID-19. The Complementary and Alternative Medicine Clinical Trials Database CoVAM (http://www.covam.in) is developed to provide the scientific community easy access to the latest information on the CAM clinical trials registered globally for COVID-19 disease. To develop the CoVAM, MySQL was used. API management was done through NodeJs (With Express), and Angular 11 was used as front end. The CoVAM is a single platform organized by ten CAM subtypes such as Acupuncture, Auricular point pressing, Ayurveda, Chiropractic, Homeopathy, Psychotherapy, Siddha, Traditional Chinese Medicine (TCM), Vitamins and dietary supplements, and Yoga/ Exercise. Each subtype has information on CAM medicines/ therapy being registered, the full title of the clinical trial, sponsor name, sponsor protocol number/ ID, age of the population, study type, actual number of participant enrolment for the trial, followed by the start date, phase, and status of the clinical trial. Each fact is linked to the clinical trial database/s from where the information was procured. Additionally, CoVAM is hyperlinked with PubMed for providing recent updates on COVID-19 and CAM research. To the best of our knowledge, CoVAM is a first-of-its-kind database that provides comprehensive information on globally registered CAMs related clinical trials conducted on COVID-19 disease.
Evaluation of the efficacy of MMX mesalazine therapy for moderate ulcerative colitis
Authors: Knyazev O. V. , Kagramanova A. V. , Lishchinskaya A. A.
Published: May 2021

Introduction. Treatment of patients with ulcerative colitis (UC) requires continuous anti-relapse therapy. Mesalazines are the firstline disease-modifying drugs for the treatment of mild to moderate UC to manage exacerbations and to induce and maintain remission.

This paper is aimed at comparing the efficacy of treatment of patients with pancolitis and left-sided ulcerative colitis of moderate severity, who received MMX mesalazine as monotherapy and MMX mesalazine combined with mesalazines in the form of microclysters and suppositories.

Materials and methods. A comparative clinical evaluation of the outcomes of treatment of patients with moderate UC who received MMX mesalazine as monotherapy (group 1) and MMX mesalazine combined with topical mesalazine (microclysters, suppositories) (group 2) was carried out. 40 patients with UC (group 1) and 46 (group 2) were examined.

Results and discussion. Two weeks after MMX mesalazine therapy initiation, 92.8% of patients in group 1 responded to MMX mesalazine therapy and continued using the drugs as monotherapy (without microclysters and suppositories). In group 1, 95.6% of patients responded to MMX mesalazine therapy and continued treatment with topical mesalazines (microclysters and suppositories). At week 12, 54.3% of 35 patients in group 1, who responded to MMX mesalazine therapy, achieved clinical remission, 45.7% achieved clinical endoscopic remission. The Mayo Score decreased from 8.0 ± 0.17 to 2.3 ± 0.3 points. At week 12, 57.1% of patients with UC in group 2, who responded to MMX mesalazine therapy, achieved clinical remission, and 42.9% achieved clinical and endoscopic remission. The Mayo Score decreased from 7.85 ± 0.14 to 2.4 ± 0.3 points. There was no statistically significant difference in the level of laboratory findings between the groups of patients at 12 weeks and at 52 weeks (p> 0.05).

Conclusion. The long-term continuous administration of MMX mesalazine in patients with pancolitis and left-sided ulcerative colitis of moderate severity as monotherapy during the year is comparable in its efficacy with combined MMX mesalazine therapy and topical forms of mesalazine.
Features of the course of gastric ulcer in different age groups
Authors: Polozova E. I. , Skvortsov V. V. , Trokhina I. E. , Nefedov N. S.
Published: May 2021

Introduction. The problem of gastric ulcer is of particular socio-economic importance and has a tremendous impact on the quality of life of people. The relevance of our study is due to an increase in the incidence of peptic ulcer in the population, the variability of the clinical picture depending on the age category of patients, and the peculiarities of the treatment of this gastrointestinal pathology.

The aim of the study is to study the features of the course of gastric ulcer in different age groups of patients under dispensary supervision in the outpatient department of the State Budgetary Healthcare Institution of the Republic of Moldova “Republican Clinical Hospital No. 5” in the period from 2017 to 2020.

Materials and methods. A retrospective analysis of outpatient records of 100 patients of different age groups with gastric ulcer who were under dispensary observation at the outpatient clinic of the Republican Clinical Hospital No. 5 in Saransk in 2017– 2020 was carried out. Statistical analysis of the data obtained was carried out using the Microsoft Office Excel program.

Results and discussion. It was found that gastric ulcer is more often observed in middle-aged and elderly patients and is accompanied by blurring of the clinical picture of the disease, in contrast to young people, who have vivid clinical manifestations of this disease. Ulcerative defects in  young and middle-aged patients are more often small in  size and are located mainly in the area of the stomach angle, and in elderly and senile patients, ulcers are localized mainly in the cardiac region, can be gigantic and often lead to the development of complications (primarily gastrointestinal intestinal bleeding).

Conclusions. The blurring of the clinical picture, the absence of pathognomonic symptoms in elderly patients determine the late diagnosis of gastric ulcer, which ultimately leads to a high incidence of complications requiring surgical intervention. In clinical practice, it is necessary to take into account these features of the course of peptic ulcer disease in elderly patients and to prescribe the necessary complex of laboratory and instrumental studies and preventive therapy in a timely manner.
Rhinitis, rhinosinusutus and phytotherapy
Authors: Shilenkova V. V.
Published: May 2021

Acute rhinitis and acute rhinosinusitis (ARS) have viral etiology in the most of cases, and their therapy is aimed at alleviating clinical symptoms and preventing new episodes. The indications for antibiotic therapy are severe bacterial ARS, ARS with complications, and recurrent bacterial ARS. Such a categorical approach is due to the increase of antibiotic resistance, which leads to the popularization of efficient phytotherapy. Modern herbal medical products comply with general recommendation and standards of efficacy, safety and quality, and their effectiveness has been proven in clinical trials along with synthetic drugs. In acute upper respiratory tract infections, herbal medical drugs stimulate the immune system, relieve clinical symptoms, and improve the patient’s quality of life. A significant emphasis in phytotherapy is given to complex drugs synthesized on the basis of phytoneering. One of such remedies is the herbal medicinal product containing the different parts of 5 medicinal herbs: Gentian root (Gentianae radix), Primrose flowers (with calyx) (Primulae flos (cum calycibus)), Common sorrel herb (Rumicis herba), Elder flowers (Sambuci flos) and Vervain herb (Verbenae herba). This herbal medicinal product shows secretolytic, secretomotor, antiinflammatory, antiviral and mild antibacterial farmacological effects. The article provides an analysis of studies in vitro and in vivo proving the anti-inflammatory effect of Sinupret®, its potentiating effect on nasal mucosa mucociliary transport as well as efficacy and safety in patients with rhinosinusitis.
Nasal decongestants in the treatment of nasal obstruction
Authors: Nikitin K. A. , Baranskaya S. V.
Published: May 2021

Nasal congestion is one of the most common symptoms of common colds and rhinitis, due to an inflammatory reaction, vasodilation, increased nasal blood flow and vascular permeability. Nasal obstruction is often a multifactorial problem, in addition to infectious causes, it can be caused by a combination of anatomical aberrations, swelling of the nasal mucosa and enlargement of the turbinates. Anatomical and structural problems, such as nasal septum deviation and nasal valve collapse, are usually treated surgically. Drug therapy of nasal obstruction is aimed at reducing edema and inflammation of the nasal mucosa. Pharmacotherapy of nasal obstruction is aimed at reducing inflammation and/or swelling of the mucous membrane. Decongestants are widely prescribed to relieve symptoms. The drugs used have different mechanisms of action and include systemic and topical drugs. This article discusses decongestants as a treatment for nasal obstruction. When applied topically, the drugs of this group act directly on the α2 and α1-adrenergic receptors of the nasal cavity, causing vasoconstriction, a decrease in the volume of the nasal conch, an increase in nasal patency, and relieving the symptoms of obstruction. The existing risk of developing side effects, both systemic and local, is reduced with atopic exposure and proper dosing of the drug used. Preferably, the use of drugs with low bioavailability. The suppression of the ciliated epithelium can be caused not only by the pathological process, but also by the composition of drugs. The value is given to the acidity of the buffer system. The optimal pH value of intranasal agents is about 6 (neutral range). The combination with anticholinesterase substances reduces the production of pathological discharge. The use of multi-component medicines allows you to restore nasal breathing and suppress excessive nasal secretion. One of the effective and safe drugs of topical action is Xylometazoline, as a monocomponent agent or in combination with ipratropium bromide.
The role of intranasal steroid therapy in the treatment of chronic sinusitis with nasal polyps
Authors: Sobolev V. P. , Bidanova D. B.
Published: May 2021

Polypoid rhinosinusitis (PRS) is a form of chronic rhinosinusitis (CRS), which is a heterogeneous group of pathological conditions based on a chronic inflammatory process of the nasal cavity and paranasal sinuses (PNS), leading to polypoid tissue formation. In most cases, T2-inflammation underlies the pathogenetic mechanism of PRS. In the presence of T2-associated conditions, the course of PRS is usually severe. The main aim of PRS treatment is to control symptoms, prolong the recurrence-free period, and restore the aeration of the PNS. The basic therapy of PRS involves the use of intranasal glucocorticosteroids (InGCS), which have a nonspecific anti-inflammatory effect by acting on different points of the pathological inflammatory process. The level of evidence for the use of InGCS is Ia: the drugs are included in Russian and foreign clinical guidelines for the treatment of polypoid rhinosinusitis. InGCS have high topical activity at low steroid doses. Mometasone furoate has an important place among this group of drugs because of its high efficacy, long-lasting therapeutic effect and optimal safety profile. The drug is officially registered for the treatment of PRS. Long-term use of mometazone furoate has been clinically observed to cause almost no atrophic nasal mucosal changes. It can be administered as monotherapy and in combination therapy over long periods of time in all phases of the treatment of PRS.
The modern view of treatment of allergic rhinitis and it’s combination with bronchial asthma
Authors: Smirnov D. S. , Kurbacheva O. M.
Published: May 2021

In recent years, there has been a significant increase in the prevalence of diseases of the nose and paranasal sinuses. Inflammatory diseases of the mucous membrane nasal cavities (rhinitis) are most commonly characterized as a syndrome in which the patient experiences some combination of persistent nasal symptoms, including rhinorrhea, sneezing, nasal congestion, itching and burning in the nasal cavity. Among the chronic forms of rhinitis, allergic rhinitis occupies a large place along with vasomotor, infectious, hypertrophic, catarrhal and atrophic rhinitis. Allergic rhinitis is a significant social and medico-economic problem, since it significantly reduces the quality of life of patients and requires significant treatment costs. This nosology is found in the practice of doctors of all specialties, however, the correct diagnosis and the appointment of adequate therapy can take many months and years. Currently, the concept of “common airways” is widely discussed, which demonstrates the close relationship between allergic rhinitis and bronchial asthma and proves that the inflammatory response can be supported and enhanced by interrelated mechanisms. Therefore, patients with allergic rhinitis should be examined for the presence of bronchial asthma. In turn, patients with bronchial asthma need to diagnose allergic rhinitis, and treatment should be aimed at suppressing allergic inflammation in both the upper and lower respiratory tract. This article discusses modern diagnostic and therapeutic approaches to patients with these diseases, which make it possible to efficiently and timely identify allergic rhinitis and initiate appropriate adequate treatment. The article also discusses the feasibility of using combined therapy with levocetirizine and montelukast in the above nosologies.
Experimental study and modeling of hydraulic jump for a suddenly expanding stilling basin using different hybrid algorithms
Authors: Gul Enes , Dursun O. Faruk , Mohammadian Abdolmajid
Published: May 2021

Hydraulic jump is a highly important phenomenon for dissipation of energy. This event, which involves flow regime change, can occur in many different types of stilling basins. In this study, hydraulic jump characteristics such as relative jump length and sequent depth ratio occurring in a suddenly expanding stilling basin were estimated using hybrid extreme learning machine (ELM). To hybridize ELM, imperialist competitive algorithm (ICA), firefly algorithm (FA) and particle swarm optimization (PSO) metaheuristic algorithms were implemented. In addition, six different models were established to determine effective dimensionless (relative) input variables. A new data set was constructed by adding the data obtained from the experimental study in the present research to the data obtained from the literature. The performance of each model was evaluated using k-fold cross-validation. Results showed that ICA hybridization slightly outperformed FA and PSO methods. Considering relative input parameters, Froude number (Fr), expansion ratio (B) and relative sill height (S), effective input combinations were Fr–B–S and Fr–B for the prediction of the sequent depth ratio (Y) and relative hydraulic jump length (Lj/h1), respectively.
RESIDÊNCIAS ESTUDANTIS UNIVERSITÁRIAS
Authors: Villarouco Vilma , Pinto Santiago Zilsa , Pereira e Silva Thanara , Alves de Almeida Adrielly , Lima Câmara Helaine
Published: May 2021

A inesperada situação de pandemia do Coronavirus tem mudado hábitos, pois a vida urbana foi substituída pelo dia-a-dia na residência, levando a população ao confinamento e à convivência com situações improvisadas para o desenvolvimento de diversas tarefas no ambiente familiar. Para além desse contexto, a literatura aponta inadequações da habitação para populações de baixa renda, geralmente em relação a questões do design de ambientes, como reflexo do dimensionamento reduzido. Com a pandemia tais questões migraram das habitações de interesse social e se instalam nos apartamentos de classe média, colocando em lados opostos os argumentos dos pesquisadores/especialistas frente ao poder do mercado imobiliário (que busca aproveitamento máximo de cada metro quadrado dos empreendimentos). Tratando de uma forma diferenciada de habitar, este artigo objetiva analisar residências universitárias sob a ótica da ergonomia aplicada aos ambientes, tendo recortado os dormitórios para o estudo das características do seu design quanto às dimensões, layout e usabilidade. O texto elenca aspectos positivos e negativos desses espaços, num momento em que se destaca a necessidade de reduzir o contato físico entre as pessoas. O trabalho aborda o problema de forma qualitativa, adotando o estudo multicasos definido a partir de uma amostra intencional, conforme o interesse da pesquisa. Ao final constata-se a restrição e inadequação na maioria dos espaços dos dormitórios estudantis analisados.
ATRIBUTOS AMBIENTAIS E DIRETRIZES PROJETUAIS EM QUARTOS DE INTERNAÇÃO PEDIÁTRICA
Authors: Schmitt Kerchner Isabela Guesser , Bins Ely Vera Helena Moro
Published: May 2021

Este trabalho parte da premissa que as características do ambiente impactam na saúde e influenciam no bem-estar e recuperação do paciente. Aborda um recorte de estudo de caso realizado em um hospital pediátrico, e tem como objetivo identificar quais atributos ambientais influenciam na percepção de bem-estar dos usuários durante a internação pediátrica. A pesquisa apresenta caráter qualitativo e adotou uma abordagem multimétodos, com o propósito de ampliar a visão do objeto de estudo e, ainda, obter resultados complementares. Os procedimentos metodológicos selecionados tiveram como objetivo avaliar o ambiente construído – a partir de visitas exploratórias, observação do comportamento e observação de traços físicos – e, obter a percepção dos usuários acerca do objeto de estudo por meio dos métodos de inquirição. Os dados obtidos por diferentes métodos possibilitaram análises em forma de textos, tabelas e fotografias, a partir de análise de conteúdo e matriz de descobertas, esta última com o intuito de sintetizar os resultados pelos diferentes métodos adotados. A partir dos métodos aplicados foi possível estabelecer a relação entre as características do ambiente e as necessidades dos diferentes usuários, respondendo ao objetivo da pesquisa: identificar os atributos ambientais que proporcionam humanização no ambiente físico. Além disso, a discussão dos resultados levou à proposição de diretrizes projetuais para a unidade de internação pediátrica segundo os princípios de humanização.
AS INFLEXÕES ENTRE A CONSERVAÇÃO DO PATRIMÔNIO CULTURAL E A SUSTENTABILIDADE
Authors: Soares Côrtes Aline , Brasileiro Teixeira Vale Marília Maria
Published: May 2021

Este trabalho aborda os desafios de interpretar e preservar o patrimônio cultural rural, relacionado às capelas e festas religiosas celebradas em capelas rurais na região do Triângulo Mineiro e Alto Paranaíba, localizada em Minas Gerais, Brasil, com vistas à sustentabilidade. O processo de modernização da atividade agropecuária ocorrido na região em meados do século XX acarretou uma mudança do modo de vida rural que dificultou o processo de salvaguarda do patrimônio cultural rural e pôs em risco as práticas de socialização e diversas expressões culturais, tanto materiais quanto imateriais. Não obstante, a região ainda preserva uma extensa gama de recursos patrimoniais dos séculos XIX e XX. Através de pesquisas históricas, do mapeamento geral dessas capelas e festas e do estudo de alguns casos paradigmáticos, este trabalho busca identificar este universo e analisar os desafios e perspectivas de sua preservação, prospectando a sustentabilidade e refletindo sobre o questionamento: "O patrimônio cultural rural pode promover a sustentabilidade em suas mais variadas esferas? "
HANS ARP
Authors: Borda Luis Eduardo , Cristina da Silva Nayara
Published: May 2021

Este artigo analisa aproximações entre as obras do arquiteto Oscar Niemeyer e do artista franco-alemão Hans Arp. Tais aproximações são vistas a partir da presença de planos com bordas sinuosas, formas ameboides que aparecem tanto na obra de Niemeyer quanto na de Arp. Uma vez que Arp é um dos pioneiros no uso de tais superfícies, o trabalho investiga até que ponto Arp pode ser considerado uma referência estética para Niemeyer. A metodologia foi acompanhar o desenvolvimento da questão do plano na arte e na arquitetura modernas e, depois, identificar a presença de tais formas tanto na obra de Arp quanto na de Niemeyer, bem como compará-las e verificar as datas em que surgem. A conclusão foi a de que existe grande similaridade entre as formas amebóides de Arp e de Niemeyer. A pesquisa também concluiu que, por ser pioneiro no uso de tais formas, Arp é provavelmente uma referência importante para a presença de tais superfícies na obra de Oscar Niemeyer. A investigação faz parte do projeto ​Arte, Arquitetura e Cidade​, desenvolvido junto ao núcleo de Pesquisa em Linguagens da Faculdade de Arquitetura e Urbanismo da Universidade Federal de Uberlândia; dentro disso, busca desenvolver investigações relacionadas ao campo das artes e suas relações com a arquitetura.
JARDIM SENSORIAL DA UFRN
Authors: Romani Elizabeth , Fernandes Florêncio de Araújo Magnólia , Cesar Bezerra Barbosa Luciano
Published: May 2021

Este trabalho apresenta o contexto de um projeto de extensão universitária para construção de um espaço não-formal do ensino de ciências e para experiências multissensoriais, bem como sua execução. As especificidades de projeto, em um contexto de restrições orçamentárias envolvidas na construção e no que pese o respeito aos parâmetros de acessibilidade, torna-o relevante para discussão e divulgação do processo. O jardim foi concebido para ser instalado no Parque das Ciências do Museu Câmara Cascudo da Universidade Federal do Rio Grande do Norte como proposta de inclusão social, especialmente de pessoas com deficiência, e de perspectiva pedagógica para o ensino de ciências, sendo ainda uma opção recreativa e uma possibilidade de divulgação temas ligados a sustentabilidade. O objetivo desse espaço é ofertar trocas de experiências e de percepções durante o percurso com públicos diversos. Diante da importância social, este trabalho objetiva relatar os procedimentos de criação e execução do projeto arquitetônico do Jardim Sensorial. Para alcançar tal objetivo foram adotadas as seguintes etapas metodológicas: visita técnica, definição das premissas do projeto, levantamento dimensional e fotográfico, desenho do percurso, análise do percurso, definição dos volumes de vegetação, definição das plantas e projeto arquitetônico. Cabe salientar que o projeto foi desenvolvido de maneira interdisciplinar, envolvendo uma equipe com professores e alunos de arquitetura, design, biologia, química e física. Espera-se que este relato contribua com projetos que envolvam a acessibilidade cultural e a inclusão de pessoas com deficiência.
Tratamiento penal de la violencia de ge?nero contra las mujeres: especial referencia a la violencia sexual
Authors: Acale Sánchez María
Published: May 2021

En este trabajo se somete a estudio el tratamiento de la violencia de ge?nero contra las mujeres, en particular, la violencia sexual en los Co?digos penales espan?ol y colombiano. La finalidad que se persigue es analizar las diferencias existentes entre ambos ordenamientos juri?dicos, asi? como las soluciones que se adoptan en cada uno de ellos para hacer frente al mismo problema social. El estudio comparado nos permitira? plantear soluciones a la vista de ambos modelos, complementa?ndolos. Se concluira? apostando ampliamente por la sensibilizacio?n legal, judicial y social como mecanismo de prevencio?n general de la violencia de ge?nero.

Palabras Claves: violencia de ge?nero, violencia sexual, discriminacio?n, perspectiva de ge?nero, prevencio?n general.

Abstract

In this work, the treatment of gender violence against women, in particular, sexual violence in the Spanish and Colombian Criminal Codes, is under study. The aim is to analyze the differences between the two legal systems, as well as the solutions adopted in each of them to deal with the same social problem. The comparative study will allow us to propose solutions to both models, complementing them. It will be concluded by broadly betting on legal, judicial and social awareness as a mechanism for the general prevention of gender violence.

Keywords: gender violence, sessual violence, discrimination, gender perspective, general prevention.

Resumo

Este trabalho aborda o tratamento da viole?ncia de ge?nero contra as mulheres, em particular a viole?ncia sexual nos co?digos penais espanhol e colombiano. A finalidade que se persegue neste estudo e? analisar as diferenc?as existentes entre ambos ordenamentos juri?dicos, assim como as soluc?o?es que de adotam em cada um deles para fazer frente ao mesmo problema social. O estudo comparado nos permitira? propor soluc?o?es a? vista de ambos modelos, complementando-nos. Como conclusa?o se aposta amplamente pela sensibilizac?a?o legal, judicial e social como mecanismo de prevenc?a?o geral da viole?ncia de ge?nero.

Palavras-chave: viole?ncia de ge?nero, viole?ncia sexual, discriminac?a?o, perspectiva de ge?nero, prevenc?a?o geral.
Lectura del contexto para el diseño y operación de un Centro de Escritura Digital en la educación media
Authors: CALLE ALVAREZ GERZON YAIR
Published: May 2021

The process of designing an Online Writing Center (OWC) for high education must respond to global and regional challenges, however, knowing the context where it is going to be established is fundamental. The foregoing, because an OWC is not a distant issue to the realities of the institutions. The purpose of this article is to present the results on reading the context of two institutions that offer high education, one public and one private, that participated in the research process. For this, the case study was adopted and questionnaires of inquiry were applied to students and teachers, from the possibilities of design and operation of the CED in the high education and the conformation of a Virtual Learning Community. The results show how the information obtained was considered for the disposition of the OWC of each of the institutions. The conclusions state that reading the institutional context is important when thinking about the structuring and operation of an OWC for secondary education.
La percepción ciudadana sobre la sostenibilidad del patrimonio mundial. El caso del centro histórico de Santa Ana de Cuenca
Authors: Molina Bárbara
Published: May 2021

The incorporation of the sustainable model in World Heritage Sites management implies a participatory approach in the identification, protection, conservation, presentation and transmission of the outstanding universal values (OUV) for future generations (UNESCO, 2017). Citizens, as relevant social actors, provide a reputation regarding cultural heritage that informs on key issues in order to achieve its sustainable management. The lack of methodologies to comprehend the relationship between society and cultural heritage from a sustainable approach is a limitation to achieve participatory management. This article provides empirical evidence on the level of sustainability that exists in the World Heritage site of Cuenca (Ecuador), from the citizen`s point of view. The statistical results reveal that its sustainability relies on a reputation that is built around multiple interconnected phenomena that determine positive or negative attitudinal patterns. The article thus contributes to the understanding of the relationship between citizenship and heritage, with emphasis on the aspects that must be addressed in order to achieve sustainable management in the historic center of Cuenca.
Estado Actual de los Proyectos para la Gestión del Riesgo en las instituciones educativas oficiales en La Comuna 8 de la Ciudad de Villavicencio, Departamento del Meta
Authors: Romero Lopez Francisco Antonio , Ramirez Espitia Jose
Published: May 2021

This article seeks to evaluate the degree of knowledge that refers to the people who are part of the official educational institutions of the Commune 8 of Villavicencio (Meta), as opposed to risk management. The research focused on its eight institutions. The results are intended to encourage regional and national studies on the status of risk management projects, ensuring that learning spaces meet the results of care and emergencies, improving the response capacity of teachers, administrative and students. The implementation of projects for risk management, educational institutions, the agenda of territorial entities, activities to prevent and avoid situations of risk that can lead to an emergency or the loss of human and material lives.
Estrategias de formación en busca de una Universidad socialmente responsable
Authors: Henríquez-Fuentes Gustavo , Higuera-Ojito Víctor Hugo , Rosano Reyes Enrique , Robles Nilka , Aragaki Alfredo
Published: May 2021

The objective of the study is to design a strategy of Corporate Social Responsibility (hereinafter RS) based on the expectations of students in higher grades of different programs of a private university in Barranquilla. Based on a correlation and clustering analysis, students' expectations of SR in the university are analyzed and classified. Among the most noteworthy results, the importance of variables with high correlation that should be prioritized in the order of investments and measurements, due to their influence with other variables is demonstrated. The study provides a definition of SR from the theoretical contribution and empirical data obtained in the research, also proposing a Social Responsibility strategy applicable to a University. Curricular reforms, relationship with the community, support for the development of teachers and the constant development of evaluation and monitoring processes regarding Social Responsibility are exposed.
Environmental and psychological research on sandpits as children's play equipment, children's play, and the importance of sandpits in children's development and cultural creation
Authors: Kasama Hiroyuki
Published: May 2021

Sandpits are commonly found in playgrounds but in a world full of high-tech entertainment is their role in the developmental growth of young children undervalued? Professor Hiroyuki Kasama, Doshisha Women's College, Japan, is exploring the impact of sandpits on children, including the
role they can play in deepening the relationship between parent and child. Sandpits first came about in Europe in the mid-19th century but have recently become unfavourable to many parents who consider them to be 'dirty' play. However, playing with sand yields important benefits, including
the use of natural materials and the fact it provides a valuable sensory experience that enables children to build on emotional, social and athletic skills. Kasama is investigating the important potential of sandpits as well as working on childcare and education programmes that use sandpits
for learning. Kasama is keen to improve the sandpit environment by standardising the type of sand used in order to make play more effective and observing the suitability of the sand by observing children's play and the reactions of their caregivers. Kasama and the team have also supervised
the installation of indoor sandpits that can be used year-round. Ultimately, by clarifying the significance and necessity of playing with sand and discovering its potential, Kasama is aiming to provide children with effective environments that promote growth and development.
Research on the formulation and effects of teaching methods that enhance learning motivation in Arabic language
Authors: Sumi Akiko , Sumi Katsunori
Published: May 2021

Although Arabic language learners and opportunities for learning the language gradually increased in Japan from 1925 when formal Arabic education began until the beginning of the 21st century, there is little research on Arabic language teaching and learning. To fill this gap, Akiko
Sumi, Kyoto Notre Dame University, Japan, is working to better understand the learning environment of the Arabic language and social characteristics of Arabic language learners in Japan. Her ultimate goal is to increase autonomous motivation for Arabic language learning among learners in Japan.
Akiko Sumi specialises in Arabic literature and language and is collaborating with Professor Katsunori Sumi of the Graduate School of Engineering, Nagoya Institute of Technology, Japan, who specialises in applied psychology. Together, the two researchers are working to develop a new hypothetical
model and refine instructional methods for teaching Arabic language. A psychological element of this work involves assessing the psychological characteristics of Arabic language learners in Japanese universities. The researchers also held an intensive Arabic language camp in Rurikei, Kyoto,
at which around 100 students were offered an appropriate environment to support and satisfy autonomy, competence, and relatedness. The researchers are investigating Arabic language learning as part of foreign language learning and second language acquisition, with a keen focus on learning
motivation as this is a key factor influencing language learning and teaching.
Инфракрасное фотоотражение полупроводниковых материалов A-=SUP=-3-=/SUP=-B-=SUP=-5-=/SUP=- ( О б з о р )
Authors: Комков О.С.
Published: May 2021

Photoreflectance is a contactless type of modulation optical spectroscopy. It is used to study the band structure features of monocrystalline semiconductors, their doping level, the composition of alloys, as well as surface and interface band bending. Using high-quality GaAs as an example, the possibilities of describing the photoreflectance lineshape by one-electron and exciton models are demonstrated. The spectra of ultrapure samples of this material exhibit an oscillating structure well described by excitonic effects. For III-V alloys, a review of photoreflectance results concerning the effect of composition and temperature on the band gap and spin-orbit splitting is carried out. Determination of the position of the Fermi level on the surface (Fermi level pinning) for III-V crystals is considered. The currently developing technique for measuring photoreflectance in the mid-infrared range (photomodulation Fourier transform infrared spectroscopy) is described in detail. It is shown that phase correction plays a decisive role in such measurements. Original results demonstrate the capabilities of this method in a wide wavelength range.
Модификация атомной и электронной структур палладия в результате растворения водорода
Authors: Немирович-Данченко Л.Ю. , Лопатина О.В. , Святкин Л.А. , Чернов И.П.
Published: May 2021

The results of a first-principle study of the features of changes in the atomic and electron structures of palladium as a result of hydrogen dissolution are presented. It is shown that the binding energy of hydrogen in palladium behaves irregularly: with an increase in the hydrogen concentration x = H/Pd up to 0.75, it increases and then decreases, taking negative values at hydrogen concentrations x over 1.5. It was found that, as a result of the dissolution of hydrogen in palladium, charge transfer is observed from Pd atoms to H atoms. The magnitude of this charge transfer increases as palladium becomes saturated by hydrogen.