bluuebunny/crossref_metadata_2025 huggingface dataset:
WOMEN LANGUAGE FEATURES IN RECODE WORLD’S TECHNOLOGY CONFERENCE: A SOCIOLINGUISTIC STUDIES
Authors: DEBY RAHMAWATI  , Resmana Elvi Citra , Indrayani Lia Maulia
Published: March 2021

This research analyzes the women language features in giving public speeches in RECODE World’s Technology Conferences. The writer used Lakoff’s on Holmes (2013) theory to analyze the data. The writer applies descriptive qualitative method by Creswell (2014). Data for this reseach is women utterance during conference. Basen on theory by Lakoff, the author discover six women language features.The result of this research shown that there are six women language feature that appear, there are lexical hedges, intensifier, superpolite form, avoidance strong swear, empty adjective, and emphatic stress.

Keyword: sociolinguistics, gender language, women language features.
Mixed Method: Students’ Ability in Applying Writing Mechanics in Analytical Exposition Text
Authors: Abbas M. Fadhly Farhy , Asy’ari Nabila Firda
Published: March 2021

Based on the English syllabus of SMA Serirama YLPI Pekanbaru, the students should be able to write in English by paying attention to the linguistics elements. One of them is the use of writing mechanics. This study aimed at investigating students’ ability in applying writing mechanics in Analytical Exposition texts and explained the factors that influence students’ ability in applying writing mechanics in the eleventh grade of SMA Serirama YLPI Pekanbaru. The design of this research was mixed method. The population of this research was all the eleventh grade students of SMA Serirama YLPI Pekanbaru with total of 41 students. Sampling technique used in this research was total sampling. The instruments used were test and interview. Based on the result of the test, the average score of students’ ability in applying writing mechanics in an Analytical Exposition text was 71,56. Moreover, based on the interview result, the factors that influence the students’ ability in applying writing mechanics were the students lack of motivation to open dictionary to find the correct spelling of words, the difference between the pronunciation and written of words make students confused, and lack of student knowledge about writing mechanics. In conclusion, the students’ ability in applying writing mechanics in an Analytical Exposition text at the eleventh grade of SMA Serirama YLPI Pekanbaru is categorized into fair level caused by several factors.
West Papuan Teachers’ Perceptions on Translanguaging Practices in EFL Classroom Interaction
Authors: Sahib Rahmawansyah , Nawing Najiba , Sari Hamra , Bin Ukka Syamsir
Published: March 2021

The belief that the West Papuan teachers applied translanguaging practice as strategy to enhance their students in ELT classroom. This study, investigated the West Papuan EFL teachers’ perceptions on translanguaging practices. It focused to explore the teachers’ knowledge and the teachers’ experience on translanguaging practice in EFL Classroom interaction in West Papuan. The participants of the study were three English language teachers (EFL) who work at state Islamic junior high school of Manokwari in West Papuan. The utterances of teachers’ interview were analyzed descriptive qualitatively using discourse analysis and the data gathered from classroom observations and semi-structured interviews were exposed to structural-coding analysis. The results showed that the EFL teachers have some perceptions about knowledge on translanguaging practice. There were translanguaging is a combination of Indonesian and English in the ELT Classroom, Translanguaging is a material transfer tool, Translanguaging is a safe and productive zone for students to do communication, Translanguaging is the moment for using mother tongue and local language in explaining material, Translanguaging is a strategy to improve and facilitate the understanding of material, Translanguaging is a strategy to enliven the classroom atmosphere. The EFL teachers also have experiences to apply translanguaging practice in ELT classroom. They used translanguaging to appreciate students in process of asking and answer the questions, to facilitate the transfer of material toward students, to assist the students in apply the target language, to respect the students’ questions that use the local language, and translanguaging as a challenge for teachers to master the local language of students.
Students’ Speaking Anxiety in English Education Study Program
Authors: Syahfutra Wandi
Published: March 2021

This study explores speaking anxiety: the identification of speaking anxiety in English education study program. Using a mixed methods approach, this research selected two different categories, students studying in English Education Department private university and those studying in English Education Department in public university as research participants. The findings suggest that the main factors of speaking anxiety causes at public university were essentially affected by nervousness and idea delivery. Nevertheless, English students in private university claimed that their dominant cause is rooted from self-confidence; considering mistakes and lecturers’ attitude during English speaking performance. This research is beneficial in enriching literature in the scope of English education department, especially in Indonesia and others state adopting English as foreign language. It is crucial to note that students’ voice is worth to listen, as a reflection for English teachers or lecturers identifying their students’ speaking anxiety to apply appropriate and a more effective learning method.
The Implementation of Hypnoteaching Method in Increasing Motivation to Learn English for Senior High School in Pekanbaru
Authors: Ardiya Ardiya , Syahfutra Wandi
Published: March 2021

This study explores hypnoteaching method to increase students’ senior high school Pekanbaru motivation in learning English. Using a quantitative approach with a quasi-experimental design and provide pre-test and post-test to the both control class groups and experimental groups where SMA Handayani students and SMA PGRI students as research participants. The findings showed that 1) low student motivation is one of the causes of low student learning outcomes, 2) a classroom atmosphere to support the learning process is not built yet, 3) teachers do not found yet the right method to increase and keep students learning motivation. Based on the results of the research data processed using the paired-sample t test, there were found significant differences, namely before and after implementing the hypnoteaching method in learning English with alpha results less than 0.05. This study is beneficial in enriching literature in the scope of English education study programs, especially in Indonesia and others adopting English as a foreign language as a matter of applying appropriate and a more effective learning methods.
REPRESENTASI KARAKTER TOKOH DALAM CERPEN RUSA-RUSA MASUK KACA KARYA MOSTHAMIR THALIB: PENDEKATAN SEMIOTIK CHARLES SANDERS PEIRCE
Authors: Sum Tengku Muhammad
Published: March 2021

This research has been motivated by literature as reflection of reality. The story ”Rusa-Rusa Masuk Kaca” is selected because the character in the story presents reality. The study of this story uses Charles Sanders Peirce’s semiotic analysis. Namely sign, object, and interprentrant. Semiotic analysis is used to analyze character representation that connect literary work with reality. The method used is qualitative descriptive with a literature study of data collection techniques.

Keywords:    Short Stories Rusa-Rusa Masuk Kaca, Semiotic Peirce, Character Representation.
TRADISI MITONI SEBAGAI PEREKAT SOSIAL BUDAYA MASYARAKAT JAWA
Authors: Boanergis Yohanes , Engel Jacob Daan , Samiyono David
Published: March 2021

The mitoni tradition is a Javanese cultural heritage that is still being held by Javanese people in the village of Tuntang, Tuntang District, Semarang District, Central Java until now. The mitoni ceremony is carried out in the seventh month of Javanese pregnancy. This study aims at examining the spiritual values of the mitoni tradition as socio-cultural “glue.” This research was motivated by dangerous facts, namely the threat of disharmony in the social community. The method applied in this study is qualitative with a descriptive approach. Data collection techniques were used in-depth interviews and observations. Interviews were conducted by giving open questions to community leaders in the village of Tuntang. In this study, the sources of information were traditional leaders as representatives of the Tuntang village community. This research was tested as a socio-cultural adhesive in Tuntang village through spiritual values, namely: 1). Ngruwat sukerta. 2). Cecawis. 3). Sembada. 4). Panampi. 5). Wilujeng. 6). Ngrumat bumi. 7). Pitutur. 8). Rukun. 9). Pitulungan. These spiritual values are symbolic of Javanese ideology which is eschatological. This value serves to maintain social harmony. The results of this study are recommended for religious leaders and traditional leaders to apply this cultural approach, by making mitoni as a socio-cultural “glue.”
Yanick Lahens und der Traum, die Welt zu bewohnen
Authors: Schrader Sabine
Published: March 2021

Le 21 mars 2019, l'auteure haïtienne Yanick Lahens inaugura la chaire annuelle »Monde francophone« au Collège de France à Paris. Dans sa conférence Littérature haïtienne: urgence(s) d'écrire, rêve(s) d'habiter, publiée
peu après, elle appelle à des narratives littéraires dépassant les perspectives eurocentriques (post-)coloniales afin de »découvrir d'autres manières d'habiter le corps, la communauté ou la langue«. Sur la base de ces réflexions,
je propose une relecture de son premier roman Dans la maison du père (1994), qui se confronte aux pratiques du corps (par exemple la danse), de la communauté et du récit. En se déployant en un kaléidoscope d'images sensuelles, le roman raconte l'enfance
et l'adolescence de la narratrice Alice jusqu'à son exil à New York en 1948. En même temps, Lahens relie la micro-histoire d'Alice à la macro-histoire d'Haïti dans les années 1930 et 1940. C'est ainsi que l'article analysera les limites et les possibilités
de rendre la maison du père et l'histoire haïtienne habitable.
Analisa Keseimbangan Energi PLTU Takalar (Punagaya) Unit 2 Berdasarkan Perubahan Beban
Authors: Saini Makmur , Hamzah Nur , Utomo Devi Prasetyo
Published: March 2021

This study aims to calculate the efficiency and heat rate of the unit 2 PLTU Takalar (Punagaya) system with the energy balance calculation method, calculate the NPHR value of PLTU Takalar (Punagaya) unit 2 when the unit is operating, and also to determine the energy loss from the conversion energy results at PLTU Takalar (Punagaya) unit 2 when the unit operates. The PLTU's Net Plant Heat Rate (NPHR) value is a very important role as an indicator of the performance of a steam power plant. The real-time NPHR value calculation using the energy balance method can be used as an evaluation material to control the operation pattern of the generator in order to obtain optimal operation. The method used in this research is to collect direct and indirect data to calculate the energy balance and NPHR of PLTU Takalar (Punagaya) unit 2 during the reliability run period. The calculations carried out include the calculation of the energy balance in the boiler, the energy balance in the steam cycle, the balance of electrical energy, the efficiency of the PLTU and NPHR systems. Based on the results of calculations that have been carried out the efficiency and NPHR of PLTU Takalar (Punagaya) unit 2 is the best during the reliability run of 32.76% and 2801.93 kcal / kWh at full load conditions with an energy loss value of 220.60 MW. The performance of PLTU Takalar (Punagaya) unit 2 during the reliability run is very good where the unit operates continuously and the NPHR value when full load fulfills the contract warranty and the maximum operating target.Â
Synergistic Effects of APOE and CLU May Increase the Risk of Alzheimer’s Disease: Acceleration of Atrophy in the Volumes and Shapes of the Hippocampus and Amygdala
Authors: An Na , Fu Yu , Shi Jie , Guo Han-Ning , Yang Zheng-Wu , Li Yong-Chao , Li Shan , Wang Yin , Yao Zhi-Jun , Hu Bin ,   Alzheimer’s Disease Neuroimaging Initiative
Published: March 2021

Background:

The volume loss of the hippocampus and amygdala in non-demented individuals has been reported to increase the risk of developing Alzheimer’s disease (AD). Many neuroimaging genetics studies mainly focused on the individual effects of APOE and CLU on neuroimaging to understand their neural mechanisms, whereas their synergistic effects have been rarely studied.

Objective:

To assess whether APOE and CLU have synergetic effects, we investigated the epistatic interaction and combined effects of the two genetic variants on morphological degeneration of hippocampus and amygdala in the non-demented elderly at baseline and 2-year follow-up.

Methods:

Besides the widely-used volume indicator, the surface-based morphometry method was also adopted in this study to evaluate shape alterations.

Results:

Our results showed a synergistic effect of homozygosity for the CLU risk allele C in rs11136000 and APOE ɛ4 on the hippocampal and amygdalar volumes during a 2-year follow-up. Moreover, the combined effects of APOE ɛ4 and CLU C were stronger than either of the individual effects in the atrophy progress of the amygdala.

Conclusion:

These findings indicate that brain morphological changes are caused by more than one gene variant, which may help us to better understand the complex endogenous mechanism of AD.
Topic modelling and opinion mining of user generated content on the internet using machine learning: An analysis of postpartum care centres in Shanghai
Authors: Jia Susan (Sixue) , Wu Banggang
Published: March 2021

In order to reach a compromise between adhering to the traditional culture and embracing the modern lifestyle, more and more Asian moms are heading towards postpartum care centres for postpartum recovery. However, research regarding the quality of care of these postpartum care centres is nearly missing from the literature. This paper investigated the status quo of the postpartum care centres in Shanghai, China from mothers’ perspectives by means of analysing the 34280 pairs of ratings and reviews posted by postpartum care centre customers on the internet with machine learning and text mining. Results show that the mothers are generally satisfied with the studied care centres. Meanwhile, the 13 major topics in the customer online reviews were identified, which provide an overview of the interaction between a mother and a care centre. In addition, weight of topic analysis suggests that the studied care centres can further improve in the areas of support team, environment, and facility.
Deterministic and probabilistic occupancy detection with a novel heuristic optimization and Back-Propagation (BP) based algorithm
Authors: Fatema Nuzhat , Farkoush Saeid Gholami , Hasan Mashhood , Malik H
Published: March 2021

In this paper, a novel hybrid approach for deterministic and probabilistic occupancy detection is proposed with a novel heuristic optimization and Back-Propagation (BP) based algorithms. Generally, PB based neural network (BPNN) suffers with the optimal value of weight, bias, trapping problem in local minima and sluggish convergence rate. In this paper, the GSA (Gravitational Search Algorithm) is implemented as a new training technique for BPNN is order to enhance the performance of the BPNN algorithm by decreasing the problem of trapping in local minima, enhance the convergence rate and optimize the weight and bias value to reduce the overall error. The experimental results of BPNN with and without GSA are demonstrated and presented for fair comparison and adoptability. The demonstrated results show that BPNNGSA has outperformance for training and testing phase in form of enhancement of processing speed, convergence rate and avoiding the trapping problem of standard BPNN. The whole study is analyzed and demonstrated by using R language open access platform. The proposed approach is validated with different hidden-layer neurons for both experimental studies based on BPNN and BPNNGSA.
PCANet based biometric system with fusion of palmprint and dorsal hand vein
Authors: kaur Surinder , Chaudhary Gopal , Dinesh kumar Javalkar
Published: March 2021

Nowadays, Biometric systems are prevalent for personal recognition. But due to pandemic COVID 19, it is difficult to pursue a touch-based biometric system. To encourage a touchless biometric system, a less constrained multimodal personal identification system using palmprint and dorsal hand vein is presented. Hand based Touchless recognition system gives a higher user-friendly system and avoids the spread of coronavirus. A method using Convolution Neural Networks(CNN) to extract discriminative features from the data samples is proposed. A pre-trained function PCANeT is used in the experiments to show the performance of the system in fusion scheme. This method doesn’t require keeping the palm in a specific position or at a certain distance like most other papers. Different patches of ROI are used at two different layers of CNN. Fusion of palmprint and dorsal hand vein is done for final result matching. Both Feature level and score level fusion methods are compared. Results shows the accuracy of upto 98.55% and 98.86% and Equal error rate (EER) of upto 1.22% and 0.93% for score level fusion and feature level fusion, respectively. Our method gives higher accurate results in a less constrained environment.
Application of radar measurement technology in 3D surveying and mapping of transmission lines
Authors: Jun Jia , Fu Rui , Jian Wang , Dong Dai Yong , Xiang Shen , Atassi Reem
Published: March 2021

This paper briefly introduces the background, significance, and development status of 3D radar technology at home and abroad, and then explains the concept, working principle, system composition, and workflow of the radar system. Combined with the current development trend of smart grids, it focuses on the application scope of this technology in the field of transmission line construction, operation, and maintenance. Then, through the specific implementation of the project cases, the daily operation and maintenance of four 500 kV transmission lines in Nanjing have played a certain guiding role. Finally, according to the development trend of smart grid and the actual demand of power system production and business integration, this paper briefly prospects the function expansion of this technology in transmission line operation evaluation, fault analysis and diagnosis, emergency rescue plan formulation, and other fields.
Influence of medical epidemic prevention and control on the development of sports events based on FPGA system and machine learning
Authors: Jing Wu
Published: March 2021

In year 2020, a large-scale outbreak of pneumonia caused by new coronavirus has affected the development of many industries and enterprises in China. Under the strong leadership of the Chinese government, the development of the epidemic situation in China has been well controlled. The development of various industries also began to show a good situation, many large-scale sports competitions also need to be restored. In order to ensure the normal development of large-scale sports events, we need to consider the development of epidemic situation to determine the time of sports events. Based on the study of FPGA theory, this paper designs a specific scheme of programming and system debugging, which includes a variety of program operations. In order to better predict the situation of the epidemic situation, this paper also uses the basic knowledge of machine learning to establish a relevant model to evaluate the situation of large-scale sports events under the development of the epidemic situation, and provide feasible suggestions for the recovery of large-scale sports events under the epidemic situation.
Research on the construction of TCFL resource database system based on artificial intelligence
Authors: Li Yanling
Published: March 2021

The teaching resource bank is very important for the education of linguistics. In the construction of teaching Chinese as a foreign language, we should first build a teaching resource library. Only in this way can we meet the requirements of the Ministry of education and achieve better teaching objectives. The purpose of the construction of teaching resources database is to make the teaching resources can be systematically and scientifically planned, stored in the computer in the form of data, and can be directly extracted from the computer when necessary, so as to realize the efficient utilization of resources. Based on the existing problems of teaching Chinese as a foreign language, this paper puts forward some suggestions on the construction of teaching resource database. In recent years, the rise of artificial intelligence technology provides a new idea for the establishment of teaching resource database. According to the basic idea of artificial intelligence, scientists have established a new database of teaching Chinese as a foreign language, updated and improved the original database, and established a new standard for teaching database according to the characteristics of artificial intelligence technology. A teaching resource database system based on teaching resources and artificial intelligence is established. The system is divided into data layer, logic layer and presentation layer. Artificial intelligence is used as a bridge connecting different parts. In the process of establishing the multimedia database of TCFL, we should develop in all aspects, and pave the way for the future research after laying a solid foundation of data.
Intelligent diagnostic analysis based on pattern recognition of DTI image
Authors: Jin Dan , Su Xiaojuan , Wang Yeqing , Shi Dai , Xu Liang
Published: March 2021

Traditional brain imaging usually does not show anomalies. Based on this, this study used DTI to find evidence that the brain structure microstructure may be abnormal, and to study the BOLD signal changes of functional magnetic resonance imaging and the changes of DTI microstructure in patients with mild traumatic brain injury. At the same time, based on literature collection and actual data, the current status of nuclear magnetic resonance diagnosis of brain trauma was collected. Moreover, this study combines the problem to improve the algorithm and propose an image diagnosis method for brain trauma to improve the cluster quality and stability. In addition, the experiment was designed to analyze the performance of the algorithm in this study. Finally, in this study, resting state functional magnetic resonance imaging was used to study the resting brain function in patients with mild cognitive impairment within one week after traumatic brain injury. The results show that the method proposed in this study has certain effects and can provide theoretical reference for related research.
Research on sports action training method based on generative confrontation network model and artificial intelligence
Authors: Yang Yang
Published: March 2021

In order to improve the effect of sports movement training, this paper builds a sports movement training model based on artificial intelligence technology based on the generation of confrontation network model. Moreover, in order to achieve the combination of model and model-free deep reinforcement learning algorithm, this paper implements the model’s guidance and constraints on deep reinforcement learning algorithm from the perspective of reward value and behavior strategy and divides the model into two situations. In one case, the existing or manually established expert rules are used as model constraints, which is equivalent to online learning by experts. In another case, expert samples are used as model constraints, and an imitation learning method based on generative adversarial networks is introduced. Moreover, using expert samples as training data, the mechanism that the model is guided by the reward value is combined with the model-free algorithm by generating a confrontation network structure. Finally, this paper studies the performance of the model through experimental research. The research results show that the model constructed in this paper has a certain effect.
Optimizations for filter-based join algorithms in MapReduce
Authors: Rababa Salahaldeen , Al-Badarneh Amer
Published: March 2021

Large-scale datasets collected from heterogeneous sources often require a join operation to extract valuable information. MapReduce is an efficient programming model for processing large-scale data. However, it has some limitations in processing heterogeneous datasets. This is because of the large amount of redundant intermediate records that are transferred through the network. Several filtering techniques have been developed to improve the join performance, but they require multiple MapReduce jobs to process the input datasets. To address this issue, the adaptive filter-based join algorithms are presented in this paper. Specifically, three join algorithms are introduced to perform the processes of filters creation and redundant records elimination within a single MapReduce job. A cost analysis of the introduced join algorithms shows that the I/O cost is reduced compared to the state-of-the-art filter-based join algorithms. The performance of the join algorithms was evaluated in terms of the total execution time and the total amount of I/O data transferred. The experimental results show that the adaptive Bloom join, semi-adaptive intersection Bloom join, and adaptive intersection Bloom join decrease the total execution time by 30%, 25%, and 35%, respectively; and reduce the total amount of I/O data transferred by 18%, 25%, and 50%, respectively.
Enhanced Kalman filter algorithm using fuzzy inference for improving position estimation in indoor navigation
Authors: Jamil Faisal , Kim DoHyeun
Published: March 2021

In recent few years, the widespread applications of indoor navigation have compelled the research community to propose novel solutions for detecting objects position in the Indoor environment. Various approaches have been proposed and implemented concerning the indoor positioning systems. This study propose an fuzzy inference based Kalman filter to improve the position estimation in indoor navigation. The presented system is based on FIS based Kalman filter aiming at predicting the actual sensor readings from the available noisy sensor measurements. The proposed approach has two main components, i.e., multi sensor fusion algorithm for positioning estimation and FIS based Kalman filter algorithm. The position estimation module is used to determine the object location in an indoor environment in an accurate way. Similarly, the FIS based Kalman filter is used to control and tune the Kalman filter by considering the previous output as a feedback. The Kalman filter predicts the actual sensor readings from the available noisy readings. To evaluate the proposed approach, the next-generation inertial measurement unit is used to acquire a three-axis gyroscope and accelerometer sensory data. Lastly, the proposed approach’s performance has been investigated considering the MAD, RMSE, and MSE metrics. The obtained results illustrate that the FIS based Kalman filter improve the prediction accuracy against the traditional Kalman filter approach.
Statistical analysis of age-related skin parameters
Authors: Meng Hong , Lin Weixuan , Dong Yinmao , Li Li , Yi Fan , Meng Qingyang , Li Yue , He Yifan
Published: March 2021

BACKGROUND: Due to the increasing interest in human anti-aging, demand for a higher quality of life, and technological advancement, the development of anti-aging skincare has great market prospects. Most cosmetic companies develop products driven by the market or focus on the mechanism of action of substances and the behavior of skin; however, little research utilizes skin parameters and large data methodology to develop skincare products. OBJECTIVE: To instruct consumers to purchase skincare products and to guide skincare research toward the development of customer-targeted products. METHODS: A total of 815 Chinese subjects (83 male; 732 female) from five different cities were included. We measured 14 indices in each subject, including moisture, transepidermal water loss (TEWL), and sebum levels. We performed multiple regression analysis to understand the relationship between skin indices and aging; a novel approach is shown using the R software. RESULTS: The exact age at which changes in each skin index occurred could be demonstrated by this method of analysis: 39, 38, 48, 46, and 56 years old with respect to the L value, Melanin, Rt, Rm, and Rz, respectively. CONCLUSION: With the use of statistical analysis, consumers can be more efficiently targeted and choose suitable products considering particular skin parameter changing points; thus, skincare companies will not only meet customer requirements but also better control budgets.
A method for enhancing speech and warning signals based on parallel convolutional neural networks in a noisy environment
Authors: Kang Ha Lim , Na Sung Dae , Kim Myoung Nam
Published: March 2021

BACKGROUND: Digital hearing aids are based on technology that amplifies sound and removes noise according to the frequency of hearing loss in hearing loss patients. However, within the noise removed is a warning sound that alert the listener; the listener may be exposed to danger because the warning sound is not recognized. OBJECTIVE: In this paper, a deep learning model was used to improve these limits and propose a method to distinguish the warning sound in speech signals mixed with noise. In addition, the improved speech and warning sound were derived by removing noise present in the classification sound signals. METHODS: To classify the sound dataset, an adaptive convolution filter that changes according to two signals is proposed. The proposed convolution filter is applied to the PCNNs model to analyze the characteristics of the time and frequency domains of the dataset and classify the presence or absence of warning sound. In addition, the CEDN model was used to improve the intelligibility of the warning and the speech in the signal based on the warning sound classification from the proposed PCNNs model. RESULTS: Experimental results show that the PCNNs model using the proposed multiplicative filters is efficient for analyzing sound signals with complex frequencies. In addition, the CEDN model was used to improve the intelligibility of the warning and the speech in the signal based on the warning sound classification from the proposed PCNNs model. CONVLUSION: We confirmed that the PCNN model with the proposed filter showed the highest training rate, lowest error rate, and the most stable results. In addition, the CEDN model confirmed that speech and warning sounds were recognized, but it was confirmed that there was a limitation in clearly recognizing speech as the noise ratio increased.
Profiling the structural determinants of aminoketone derivatives as hNET and hDAT reuptake inhibitors by field-based QSAR based on molecular docking
Authors: Wang Panpan , Jing Chenxi , Yu Pei , Lu Meng , Xu Xiaobo , Pei Qinglan , Yan Fengmei
Published: March 2021

BACKGROUND: Bupropion, one of the dual norepinephrine and dopamine reuptake inhibitors (NDRIs), is an aminoketone derivative performed effect in improving cognitive function for depression. However, its therapeutic effect is unsatisfactory due to poor clinical response, and there are only few derivatives in pre-clinical settings. OBJECTIVE: This work attempted to elucidate the essential structural features for the activity and designed a series of novel derivatives with good inhibitive ability, pharmacokinetic and medicinal chemistry properties. METHODS: The field-based QSAR of aminoketone derivatives of two targets were established based on docking poses, and the essential structural properties for designing novel compounds were supplied by comparing contour maps. RESULTS: The selected two models performed good predictability and reliability with R2 of 0.8479 and 0.8040 for training set, Q2 of 0.7352 and 0.6266 for test set respectively, and the designed 29 novel derivatives performed no less than the highest active compound with good ADME/T pharmacokinetic properties and medicinal chemistry friendliness. CONCLUSIONS: Bulky groups in R1, bulky groups with weak hydrophobicity in R3, and potent hydrophobic substituted group with electronegative in R2 from contour maps provided important insights for assessing and designing 29 novel NDRIs, which were considered as candidates for cognitive dysfunction with depression or other related neurodegenerative disorders.
Суб’єкти адміністративної відповідальності за незаконне використання об’єктів прав інтелектуальної власності.
Authors:   Alfred Nobel University, Майданевич А.Г.
Published: March 2021

У статті проаналізовано основні підходи до питань адміністративної відповідальності юридич- них осіб, що існують в адміністративно-правовій доктрині, здійснено аналіз чинного законодавства України, нормами якого передбачено відповідальність юридичних осіб у сфері незаконного вико- ристання об’єктів права інтелектуальної власності. Питання адміністративної відповідальності юри- дичних осіб завжди мали актуальність і практичну значущість, особливо це стосується дослідження проблемних питань, пов’язаних із суб’єктами адміністративної відповідальності за незаконне вико- ристання об’єктів права інтелектуальної власності. Юридична відповідальність у сфері охорони ін- телектуальної власності регулюється значною кількістю актів вітчизняного і міжнародного законо- давства, серед яких, крім норм спеціального законодавства, провідну роль відіграє адміністратив- не законодавство. Проте до недоліків спеціальних законів у сфері охорони інтелектуальної власнос- ті, за виключенням Законів України «Про охорону прав на сорти рослин» та «Про авторське право і суміжні права», норми яких встановлюють відповідальність юридичних осіб. На відміну від зазначе- них спеціальних законодавчих актів інші спеціалізовані закони лише включають позначення, що за- хист особистих немайнових і майнових прав суб’єктів права з інтелектуальної власності здійснюється в порядку, встановленому адміністративним, цивільним і кримінальним законодавством. На сьогод- ні чинний Кодекс України про адміністративні правопорушення встановлює адміністративну відпові- дальність лише фізичних осіб.
Міжнародна правотворчість в умовах глобалізації та вдосконалення для України.
Authors:   Alfred Nobel University, Окопник О.М. , Ю.В. Ю.В.
Published: March 2021

Правотворчість має вагоме значення для кожної країни, яка спрямовує свою діяльність на до- сягнення правової держави. Саме для цього державні органи наділяють повноваженнями щодо пра- воутворення. Правотворчість регулює суспільні відносини, які складаються між людьми. Міжнародна правотворчість – це засоби регулювання відносин між державами. Так, за допомогою прийняття Ста- туту Організації Об’єднаних Націй і Статуту Міжнародного Суду з 1945 р. почався активний розвиток міжнародних норм на основі принципів, що надають правовим нормам юридичної обов’язковості, а в подальшому став результатом правотворчості. У міжнародному праві правом правотворчості на- ділені держави, міжнародні та міжурядові організації. Вони приймають нормативно-правовий акт у вигляді договору. Таким чином, суб’єкти міжнародного права уповноваженні мати законодавчу ініці- ативу, що сприяє утворенню правотворчого процесу в міжнародному праві, де суб’єкти можуть ство- рювати правову норму на основі згоди між державами або міжнародними організаціями. Такі згоди між суб’єктами міжнародного права закріплюють правила поведінки або встановлюють обов’язкові для виконання правові норми.
Процесуальні особливості, проблематика і негативні тенденції зростання порушення професійних прав адвокатів та гарантій їх діяльності.
Authors:   Alfred Nobel University, Антонюк О.В.
Published: March 2021

У статті детально висвітлено проблематику та негативні тенденції зростання кількості обшуків в адвокатів і в адвокатських об’єднаннях; процесуальні особливості неврегульованості процедури за- хисту адвокатської таємниці; комплексна законодавча невизначеність за відсутності прямих проце- суальних норм захисту адвокатської діяльності; прогалини в запобіганні забезпечення професійних прав та гарантій адвокатської діяльності. Також наведено приклади порушення професійних прав та гарантій адвокатської діяльності та адвокатської таємниці. Застосовано метод наукового досліджен- ня, спостереження, аналізу, узагальнення. Визначено тенденції зростання зазначених порушень та виокремлено рекомендації і способи їх врегулювання в умовах сучасного розвитку права та держа- ви в Україні. Конституційне право на професійну правову допомогу має розглядатися як один із клю- чових елементів механізму здійснення права особи на судовий захист (ст. 55 Конституції України) та здійснення повного обсягу конституційних прав і свобод громадян. Відповідно до ст. 64 Конституції України конституційне право кожного на професійну правову допомогу не може бути обмежене. Ніх- то – ні громадяни, ні держава – не має права перешкоджати наданню правової допомоги. Однак слід зазначити, що ці та інші гарантії адвокатської діяльності спрямовані на надання клієнтам ефективної юридичної (правової) допомоги та є системою гарантій, гарантованих державою від будь-якого зо- внішнього впливу.
Реальное шоу и театральная культура: проблемы взаимного перечеркивания.
Authors:   Alfred Nobel University, Рябовол Л.Т.
Published: March 2021

На сучасному етапі становлення перед Україною постали складні питання, пов’язані із серйоз- ними викликами її суверенітету, у зв’язку з чим актуалізувалася проблематика національної безпеки, шляхів та способів її забезпечення. Вирішення цих питань передбачає, насамперед, визначення по- няття, структури та функцій національної безпеки. Поняття «національна безпека України» позначає важливе суспільно-політичне явище зі складною організаційно-правовою структурою, отже, його не- обхідно вивчати з позицій системного підходу. Мета статті – розглянути національну безпеку України як систему, зокрема: провести аналіз наукових позицій щодо структури і функцій національної без- пеки та її забезпечення і виявити їх недоліки; викласти авторське бачення структури системи націо- нальної безпеки та її забезпечення. Системний підхід дозволяє розглянути національну безпеку та її забезпечення як систему – цілісність, єдність компонентів, серед яких: мета, завдання, принципи та функції відповідної діяльності; суб’єкти (державні й недержавні) забезпечення національної безпе- ки, їх повноваження і компетенції, взаємоузгоджена діяльність (взаємодія); об’єкт, на забезпечення безпеки якого й спрямована система, а саме – національні інтереси й цінності, для охорони від пев- них загроз і небезпек яких створюються уповноважені на те суб’єкти, а охорона цих об’єктів і стано- вить сутність діяльності із забезпечення національної безпеки; зміст такої діяльності як сукупність правових, організаційно-управлінських, інших заходів, засобів, форм, методів, технологій її здійснен- ня, інструментів і механізмів забезпечення національної безпеки.
Місто як населений пункт: місце в системі адміністративно-територіального устрою України
Authors:   Alfred Nobel University, Шкабаро В.М.
Published: March 2021

Стаття присвячена дослідженню місця міста як населеного пункту в системі адміністративно- територіального устрою держави, доля якої значною мірою визначається розвитком її міст. Обґрун- товано авторську позицію про значення та особливий вплив території держави та її територіальних одиниць на розвиток і функціонування держави. Сьогодні майже всі держави поділяють свою тери- торію на певні одиниці, в межах яких реалізується державна та місцева влада. У кожній державі існує свій адміністративно-територіальний устрій. Проведено аналіз праць щодо визначення понять «дер- жавний устрій», «територіальний устрій», «адміністративно-територіальний устрій», «адміністратив- но-територіальний поділ». Розглянуто відмінності цих понять. Наведено та проаналізовано норми Конституції України, які визначають конституційні основи територіального устрою, адміністративно- територіального устрою та статусу міст України. Автор зазначає, що сьогодні місто – це основна адмі- ністративно-територіальна одиниця, яка є елементом структури великих і середніх регіонів України. Наведено позицію щодо ролі міст у державі.
Акти Конституційного Суду України: окремі аспекти.
Authors:   Alfred Nobel University, Мілова Т.М.
Published: March 2021

Розглянуто окремі аспекти реформування компетенції, внутрішньої організаційної структури Конституційного Суду України, що вплинуло на юридичну природу актів Конституційного Суду Укра- їни. Проаналізовано систему актів Конституційного Суду України, їх особливості, порядок та гаран- тії їх виконання. Згідно з чинним законодавством України актами Конституційного Суду України є рі- шення, висновки, ухвали, постанови та забезпечувальні накази. Акцентовано увагу на змінах чинно- го законодавства щодо розширення переліку питань, з яких Конституційний Суд України, а саме його Велика палата, надає висновки. Зокрема розглянуто норму, що закріплює за Конституційним Судом України вкрай важливе виключне право превентивного конституційного контролю щодо кола пи- тань, які пропонуються для винесення на всеукраїнський референдум за народною ініціативою. Ак- центовано на дискусійності питання щодо перевірки нормативно-правових актів Верховної Ради Ав- тономної Республіки Крим щодо відповідності не лише Конституції, але й законам України.
The association of smoking status with SARS-CoV-2 infection, hospitalisation and mortality from COVID-19: A living rapid evidence review with Bayesian meta-analyses (version 11)
Authors: Simons David , Shahab Lion , Brown Jamie , Perski Olga
Published: March 2021

AIMS: To estimate the association of smoking status with rates of i) infection, ii) hospitalisation, iii) disease severity, and iv) mortality from SARS-CoV-2/COVID-19 disease.
 

DESIGN: Living rapid review of observational and experimental studies with random-effects hierarchical Bayesian meta-analyses. Published articles and pre-prints were identified via MEDLINE and medRxiv.
 

SETTING: Community or hospital. No restrictions on location.

PARTICIPANTS: Adults who received a SARS-CoV-2 test or a COVID-19 diagnosis.

MEASUREMENTS: Outcomes were SARS-CoV-2 infection, hospitalisation, disease severity and mortality stratified by smoking status. Study quality was assessed (i.e. ‘good’, ‘fair’ and ‘poor’).

FINDINGS: v11 (searches up to 2021-02-16) included 405 studies with 62 ‘good’ and ‘fair’ quality studies included in unadjusted meta-analyses. 121 studies (29.9%) reported current, former and never smoking status with the remainder using broader categories. Recorded smoking prevalence among people with COVID-19 was generally lower than national prevalence. Current compared with never smokers were at reduced risk of SARS-CoV-2 infection (RR = 0.71, 95% Credible Interval (CrI) = 0.61-0.82, τ = 0.34). Data for former smokers were inconclusive (RR = 1.03, 95% CrI = 0.95-1.11, τ = 0.17) but favoured there being no important association (4% probability of RR ≥1.1). Former compared with never smokers were at increased risk of hospitalisation (RR = 1.19, CrI = 1.1-1.29, τ = 0.13), greater disease severity (RR = 1.8, CrI = 1.27-2.55, τ = 0.46) and mortality (RR = 1.56, CrI = 1.23-2, τ = 0.43). Data for current smokers on hospitalisation, disease severity and mortality were inconclusive (RR = 1.1, 95% CrI = 0.99-1.21, τ = 0.15; RR 1.26, 95% CrI = 0.92-1.73, τ = 0.32; RR = 1.12, 95% CrI = 0.84-1.47, τ = 0.42, respectively) but favoured there being no important associations with hospitalisation and mortality (49% and 56% probability of RR ≥1.1, respectively) and a small but important association with disease severity (83% probability of RR ≥1.1).

CONCLUSIONS: Compared with never smokers, current smokers appear to be at reduced risk of SARS-CoV-2 infection while former smokers appear to be at increased risk of hospitalisation, greater disease severity and mortality from COVID-19. However, it is uncertain whether these associations are causal.

v7 of this living review article has been published in _Addiction_ [https://doi-org.libproxy.ucl.ac.uk/10.1111/add.15276]
Fish Health Management Considerations in Recirculating Aquaculture Systems – Part 2: Pathogens
Authors: Yanong Roy
Published: March 2021

Recirculating aquaculture systems, also known as water reuse systems, have become more and more popular. Recirculating systems are commonly found in aquaculture facilities, wholesale and retail tropical fish facilities, and public aquaria. However, in order to successfully and most efficiently operate one of these systems, a goodunderstanding of fish health management considerations is critical. This circular is Part 2 in a three-part seriesdealing with management of fish health in recirculating systems. It explains the role of pathogens (potential disease-causing organisms) in these systems. Published December 2003.

Cir 121/FA100: Fish Health Management Considerations in Recirculating Aquaculture Systems?Part 2: Pathogens (ufl.edu)
Fish Health Management Considerations in Recirculating Aquaculture systems - Part 3: General Recommendations and Problem-Solving Approaches
Authors: Yanong Roy
Published: March 2021

Both the popularity and use of recirculating systems have increased, and these systems are now commonly used in aquaculture facilities, wholesale and retail tropical fish facilities, and public aquaria. This circular is Part 3 of a three-part series dealing with fish health management in recirculating aquaculture systems. This document provides general recommendations for choosing, setting up, and running a system, as well as some problem-solving approaches to help maintain a well-managed system – regardless of its purpose. This basic information should assist the beginner or intermediate-level aquaculturist interested in maintaining healthy fish in recirculating systems. This document is Circular 122, one of a series from the Department of Fisheries and Aquatic Sciences, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Original publication date December 2003.

Cir 122/FA101: Fish Health Management Considerations in Recirculating Aquaculture systems?Part 3: General Recommendations and Problem-Solving Approaches (ufl.edu)
Florida Solid and Hazardous Waste Regulation Handbook: Resource Conservation and Recovery Act (RCRA)
Authors: Olexa Michael T. , Leviten Aaron , Samek Kelly
Published: March 2021

The Resource Conservation and Recovery Act (RCRA) manages all aspects of solid and hazardous wastes. RCRA has separate requirements for generators of wastes, transporters of wastes, and owner/operators of facilities for treatment, storage, or disposal of hazardous waste. The requirements of RCRA include: permitting by EPA and exhaustive recordkeeping. The requirements are intended to track the movement and handling of the waste until it reaches final disposal. This is known as the cradle-to-grave approach to monitoring wastes. This is EDIS document FE444, a publication of the Department of Food and Resource Economics, Florida Cooperative Extension Service, UF/IFAS, University of Florida, Gainesville, FL. Published December 2003.

https://edis.ifas.ufl.edu/fe444
Individual Retirement Accounts and Other Retirement Savings Plans
Authors: Turner Josephine
Published: March 2021

For many years, Congress has recognized that saving for retirement is a worthwhile social goal and should be encouraged by the government. The federal government has encouraged the growth of private pension and savings plans through the use of various tax incentives. This publication will focus mainly on individual retirement accounts (IRAs), but other plans such as simplified employee pensions (SEPs), 401-K plans, and Keogh plans will be discussed, too. This document is FCS5258, one of a series of the Department of Family, Youth and Community Sciences, University of Florida, UF/IFAS, Gainesville 32611. First published: September 2003.