bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of Age on the Expression of Ceramide-Metabolizing Enzymes in the Adipose Tissue of Patients with Coronary Artery Disease
Authors:   Scientific and Research Institute of Complex Cardiovascular Problems, Belik E.V. ,   Kemerovo, Russian Federation, Dolmatova S.E. ,   Scientific and Research Institute of Complex Cardiovascular Problems; Kemerovo, Russian Federation,   Kemerovo State Medical University; Kemerovo, Russian Federation, Dyleva Yu.A. ,   Scientific and Research Institute of Complex Cardiovascular Problems; Kemerovo, Russian Federation, Uchasova E.G. ,   Scientific and Research Institute of Complex Cardiovascular Problems; Kemerovo, Russian Federation, Gorbatovskaya E.E. ,   Scientific and Research Institute of Complex Cardiovascular Problems; Kemerovo, Russian Federation,   Kemerovo State Medical University; Kemerovo, Russian Federation, Gruzdeva O.V. ,   Scientific and Research Institute of Complex Cardiovascular Problems; Kemerovo, Russian Federation,   Kemerovo State Medical University; Kemerovo, Russian Federation
Published: January 2025

Aim. To identify the features of gene expression of de novo synthesis enzymes and ceramide (Cer) degradation enzymes in fat depots of various localization in patients with cardiovascular diseases, depending on age.
Design. A single-center prospective clinical study.
Materials and methods. 60 patients with coronary artery disease (CAD) were examined. Biopsies of subcutaneous (SAT), epicardial (EAT), and perivascular adipose tissue (PVAT) were obtained during coronary bypass surgery. Gene expression of de novo Cer synthesis enzymes (C1 and C2 subunits of serine palmitoyltransferase — SPTLC1, SPTLC2; ceramide synthase 1–6 — CERS1–6; dihydroceramide desaturase — DEGS1) and degradation of Cer (acid ceramidase — ASAH1, sphingomyelin synthase 1 and 2 — SGMS1 and SGMS2,) were evaluated using quantitative
polymerase chain reaction.
Results. The expression of Cer de novo synthesis enzyme genes is maximal in the ventricular tract of persons 75 years and older, with a high level of CERS5 and CERS6 (producing Cer14:0 and Cer16:0) in EAT — in persons 60–74 years old. The highest expression of the CERS2 gene (synthesizing Cer 20:0, 22:0, 24:0, 24:1, 26:0) in EAT, it was observed in the group of people aged 60–74 years, in PVAT — 75 years and older. Increased expression of the ASAH1 gene (degradation of Cer to sphingosine and free fatty acids) was detected in patients 75 years and older, SGMS1 and SGMS2 genes (conversion of Cer to sphingomyelin) — in persons 60–74 years of age in all AT. These results indicate the modulation of synthesis and accumulation of Cer in the AT ventricular localization with age.
Conclusion. The AT of patients with coronary heart disease differed in the level of expression of de novo synthesis enzyme genes and Cer degradation depending on age. It is likely that the AT ventricular localization undergoes deeper age-related remodeling, which can lead to the accumulation of Cer in the EAT and PVAT.
Keywords: enzyme gene expression, ceramide synthesis, ceramide degradation, age, coronary heart disease.
THE EFFECT OF BIOLOGICS ON THE MICROGRAIN OF PEAS IN PEAT CONDITIONS
Authors:   Ufa Federal Research Center of the Russian Academy of Sciences, A.A. Kutlubaev , R.S. Irgalina ,   Bashkir State Agrarian University, N.G. Kurmasheva ,   Bashkir State Agrarian University
Published: January 2025

This article presents the results of research on the effect of biopreparations on the
micrograin of peas according to the main biometric, biological and biochemical
parameters in peat conditions. According to the data obtained, the most effective
options were those in which mycorrhiza in liquid form was used.
IMPROVING THE ECONOMIC EFFICIENCY OF THE ENTERPRISE
Authors:   Bashkir State Agrarian University, Z.A. Zalilova , A.R. Ziazetdinova ,   Bashkir State Agrarian University
Published: January 2025

The article discusses the process of increasing the economic efficiency of an
enterprise, which consists in improving the effectiveness of its activities, increasing
profits, reducing costs and optimizing the use of resources. This is achieved by
optimizing business processes, introducing new technologies and management
methods, as well as actively applying marketing strategies. As a result, the
competitiveness of the enterprise in the market increases and the well-being of its
employees and shareholders improves.
PROMISING DIRECTIONS FOR IMPROVING THE FINANCIAL RESULTS OF ENTERPRISES IN MODERN CONDITIONS
Authors:   Bashkir State Agrarian University, Z.A. Zalilova , A.R. Ziazetdinova ,   Bashkir State Agrarian University, E.V. Zakharov ,   Bashkir State Agrarian University, E.E. Abzalilova ,   Bashkir State Agrarian University
Published: January 2025

The scientific article discusses promising areas for improving the financial results
of enterprises in modern conditions. The main focus is on reducing the cost of
production and increasing sales volume, which contributes to the growth of profits and
the development of companies. The principles and triggers of development are also
discussed, profit and profitability indicators are analyzed, reserves for increasing the
book value of the enterprise are identified. The article is relevant for managers and
specialists involved in financial management and enterprise development.
CONTRIBUTION TO INDUSTRIAL SAFETY OF SMALL FORMS OF ECONOMY ON THE EXAMPLE OF THE REPUBLIC OF BASHKORTOSTAN
Authors:   Bashkir State Agrarian University, A.R. Ziazetdinova , Z.A. Zalilova ,   Bashkir State Agrarian University
Published: January 2025

The scientific article examines the importance of small enterprises in the agroindustrial complex in terms of providing the population with high-quality food
products and strengthening regional self-sufficiency to address issues of food security
in both the region and the country as a whole. The study examines the advantages of
these micro-enterprises compared to larger agricultural corporations and suggests
possible areas for increasing their efficiency. The authors propose solutions that
guarantee the success of this category of enterprises in the agro-industrial complex of
the Republic of Bashkortostan.
THE USE OF FEED PROBIOTICS IN POULTRY FARMING
Authors:   Bashkir State Agrarian University, E. V. Danilova , A. F. Khabirov ,   Bashkir State Agrarian University
Published: January 2025

Poultry farming is one of the dynamically developing branches of animal
husbandry in many countries. Antibiotics are used as growth stimulants in the agroindustrial complex to improve the efficiency of feed conversion, but the effectiveness
of these drugs on the body decreases due to the fact that pathogenic microorganisms
quickly develop antibiotic resistance. In this regard, one of the main areas of research
is the search for alternative growth stimulants for industrial poultry farming. The
purpose of this review is to analyze the scientific literature on the use of probiotics in
poultry farming. In animal husbandry, probiotics are introduced as an alternative to
antibiotics, which are mostly represented by bacteria belonging to the normal,
physiologically and evolutionarily based flora of the intestinal tract, of interest as
modulators of intestinal cell signals, competitors against pathogenic bacterial species.
Probiotic feed additives have a beneficial effect on the development and growth of farm
animals and birds, forming a healthy microbiocenosis. Microorganisms inhabiting the
gastrointestinal tract are involved in providing poultry with nutrients, vitamins,
hormones, produce enzymes, form immunity and prolong the productive life of poultry.
The intestinal bacteria of poultry include bifidobacteria, streptococci, lactobacilli,
lactate-fermenting bacteria, eubacteria, bacteroids and enterobacteria, which act as a
highly sensitive indicator system. A change in the ratio between obligate species of
microorganisms of the digestive tract does not always have a positive effect on
metabolic processes and the state of health of poultry. Maintaining a healthy
microbiome with probiotics is a safe way to combat dysbiosis and related infections.
Atlantodentoplasty using the anterior retropharyngeal approach for treating irreducible atlantoaxial dislocation with atlantodental bony obstruction: a retrospective study
Authors: Shao Jia , Han Yun Peng , Gao Yan Zheng , Gao Kun , Mao Ke Zheng , Zhang Xiu Ru
Published: January 2025

Study Design: This was a retrospective study.Purpose: The current study aimed to investigate the clinical efficacy of atlantodentoplasty using the anterior retropharyngeal approach against irreducible atlantoaxial dislocation with atlantodental bony obstruction.Overview of Literature: In cases of atlantoaxial dislocation with atlantodental bony obstruction, owing to the presence of an osteogenic mass between the atlas and odontoid process, reduction is challenging to complete using the posterior approach. Transoral odontoidectomy is technically demanding and is associated with several risks.Methods: The clinical data of 26 patients diagnosed with irreducible atlantoaxial dislocation complicated by atlantodental bony obstruction were analyzed retrospectively. All patients underwent anterior retropharyngeal atlantodentoplasty, followed by posterior occipitocervical fusion. Details including surgical duration and blood loss volume were recorded. Radiographic data such as the anterior atlantodental interval, O–C2 angle, space available for the cord, clivus–canal angle, and cervical medullary angle, and clinical data including the Japanese Orthopedic Association (JOA) score were assessed. The fusion time of the grafted bone and the development of complications were examined.Results: In patients undergoing anterior retropharyngeal atlantodentoplasty, the surgical duration and blood loss volume were 120.1±16.4 minutes and 100.6±33.5 mL, respectively. The anterior atlantodental interval decreased significantly after the surgery (p <0.001). The O–C2 angle, space available for the cord, clivus–canal angle, and cervical medullary angle increased significantly after the surgery (p <0.001). The JOA score during the latest follow-up significantly increased compared with that before the surgery (p <0.001). The improvement rate of the JOA score was 80.8%±18.1%. The fusion time of the grafted bone was 3–8 months, with an average of 5.7±1.5 months. In total, 11 patients presented with postoperative dysphagia and three with irritating cough. However, none of them exhibited other major complications.Conclusions: Anterior retropharyngeal atlantodentoplasty can anatomically reduce the atlantoaxial joint with a satisfactory clinical outcome in patients with irreducible atlantoaxial dislocation with atlantodental bony obstruction.
Typical errors when performing thermal engineering calculations of facade translucent structures
Authors: Gutora T. V. , Verkhovsky A. A.
Published: January 2025

The main regulatory requirements and typical errors in the performance of thermal engineering calculations of facade translucent structures (FTS) are considered.The assessment of the influence of incorrect or erroneous choice of parameters of thermal engineering calculations on the calculation model and calculation results is given.The analysis was carried out taking into account the current regulatory documents for conducting thermal engineering calculations and laboratory testing of the FTS.
A EXPERIMENTAÇÃO COMO PROMOTORA DE APRENDIZAGEM DO CONCEITO DE REAÇÃO QUÍMICA NO NONO ANO DO ENSINO FUNDAMENTAL
Authors: Borba Sabrina , Luca Anelise Grünfeld de
Published: January 2025

O presente artigo é resultado da intervenção pedagógica do Estágio Supervisionado III do curso de Licenciatura em Química do Instituto Federal Catarinense Campus Araquari. Teve como objetivo principal abordar os conceitos químicos referentes ao estudo das reações químicas, utilizando a experimentação investigativa e a elaboração de vídeos pelos estudantes do 9º ano do Ensino Fundamental. A questão problema que orientou a intervenção pedagógica foi: Como a experimentação investigativa favorece o ensino e a aprendizagem dos conceitos químicos relacionados com o estudo das reações químicas pelos estudantes do 9º ano? Inicialmente foram entregues proposições iniciais no intuito de identificar o conhecimento prévio dos estudantes, em seguida foi solicitado a representação em forma de desenhos do significado da química. Em sequência os estudantes realizaram experimentos de cunho investigativo referentes ao tema reações químicas, que possibilitaram as discussões sobre o tema. Após foram apresentadas e discutidas as explicações quanto aos conteúdos conceituais que envolviam o tema de reações químicas. Como instrumentos avaliativos os estudantes elaboraram relatórios sobre os experimentos realizados e a produção de um vídeo que explicitasse uma experimentação relacionada ao tema. Finalmente responderam algumas proposições finais, que exigiram posicionamentos frente a aspectos cotidianos vivenciados pelos estudantes e realizaram avaliações sobre as aulas desenvolvidas pela licencianda. Por meio dos resultados obtidos percebeu-se que a maioria dos estudantes conseguiu relacionar o cotidiano com os conceitos científicos desenvolvidos em sala de aula. Percebeu-se que os estudantes não tinham vivenciado e realizado experimentações nas aulas de ciências, o que provocou sentimentos de motivação e inovação, influenciando de forma positiva no engajamento com as atividades propostas pela licencianda. Também foi possível notar o reconhecimento sobre a importância do estudo das reações químicas e da aquisição novos conhecimentos. As vivências possibilitadas na intervenção pedagógica se mostraram efetiva tanto na formação docente quanto promotora de aprendizagens aos envolvidos nesse processo.
DYE DEGRADATION AND METAL-SENSING ACTIVITY BY BIOSYNTHESIZED SILVER NANOPARTICLES USING Artemisia Vulgaris EXTRACT
Authors: Neopaney Gokul , Sangeeta Jha
Published: January 2025

Silver nanoparticles have been extremely significant because of their unique qualities, such as their ability to change size and form based on optical, antibacterial, and electrical properties. The current investigation used an aqueous extract from leaves of Artemisia vulgaris (Teti-Pati) to study the synthesis of silver nanoparticles (AgNPs). Plant extracts include biomolecules that are strong enough to convert metal ions to nanoparticles (NPs) using biosynthesis. Various characterization techniques were used like UV-visible spectroscopy, Fourier transform infrared spectroscopy, Scanning electron microscopy, X-ray diffraction spectroscopy, and atomic force microscopy for synthesized AgNPs. The UV-visible absorption spectrum of the bio-reduced sample interpreted the peak around 415 nm, which corresponded to the surface plasmon resonance of silver nanoparticles. The broad, strong peak at 3269 cm-1 showed the association of the -OH group of compounds of extract in reducing silver ions. SEM and AFM confirmed the morphology of the synthesized nanoparticles. The SEM image showed the spherical and polycrystalline AgNPs within the agglomerated form. A colorimetric method was used for metal sensing in an aqueous medium without modification of AgNP suspension. It was found that AgNPs sense selectively Hg2+ ions. Additionally, the synthesized AgNPs demonstrated excellent catalytic activity on the dye degradation.
История изучения Ватиканского и Парижского списков рукописей Гомилий Иакова Коккиновафского
Authors: Федотов Дмитрий Александрович
Published: January 2025

Статья посвящена истории изучения Ватиканского (Vat. gr. 1162) и Парижского (Paris gr. 1208) списков лицевых рукописей Гомилий Иакова Коккиновафского. Рассматриваются работы отечественных и зарубежных исследователей рукописей Гомилий и показывается специфика их изучения. Особое внимание уделено диссертации К. Линарду. В статье прослежена эволюция интереса к рукописям и оценки их как явления византийской культуры. В заключении говорится о большом потенциале дальнейшего изучения рукописей на основе комплексного анализа текста и изображений.

The article is devoted to the history of studying the Vatican (Vat. gr. 1162) and Parisian (Paris gr. 1208) lists of obverse manuscripts of the Homilies by Iakovos of Kokkinobaphos. The works of domestic and foreign researchers of the manuscripts of Homilies are considered as well as the specifics of their studies. Special attention is paid to K. Linardu’s dissertation. The article traces the evolution of interest in manuscripts and their evaluation as a phenomenon of the Byzantine culture. In conclusion, it is said about the great potential for further study of manuscripts based on a comprehensive analysis of text and images.
Numerical Comparison of PI and Neural Network-Based Controllers for the Hydrostatic Unit in Hydro-mechanical Transmissions of Self-propelled Vehicles
Authors: Dang Ngoc Danh , Bui Viet Duc , Nguyen Thi Hue , Vu Cong Canh
Published: January 2025

The application of hydro-mechanical transmissions is recently the trend in agricultural vehicles where a continuously variable transmission ratio has advantages. Hydro-mechanical transmissions provide efficient power transfer while maneuverability is still maintained, and therefore, fuel efficiency is enhanced. Nevertheless, the main issue in their employment is a precise control of the hydrostatic unit, whose physical characteristics are highly nonlinear and affected by unknown disturbances. In order to exploit the advantages of the system, the transmission ratio of the hydrostatic unit needs to be controlled properly to maintain the optimal working point of the internal combustion engine (ICE). This article presents numerical comparison results of a proportional-integral (PI) and a neural network (NN) based controller applied to the hydrostatic unit of a hydro-mechanical transmission system, which was designed to be deployed on a self-propelled agricultural vehicle. The controls were established in a discrete-time domain aiming at a practical outcome, where the control algorithm could be implemented on an industrial computer to perform the control tasks.
Bridging the gap: how university music programs can integrate contemporary music creation into elementary school curriculum
Authors: Chifu Tarpagkos Ana
Published: January 2025

In this paper, integration of contemporary classical music creation in elementary school curricula is presented as a key to boosting student engagement and creativity. It identifies a gap between traditional music pedagogy and modern practice whose music pedagogy limits students' engagements with music outside of school. Through the use of university music programs for the development of professional development and collaborative curriculum development, educators become more inclusive in the environment of music education. Among many innovative practices including graphic scores, Sound painting, improvisation, instrument making and body percussion, the study reviews some ways of creating freedom and cultural understanding for the non-music students.
Jugendpolitik während der COVID-19-Pandemie: Jenseits des Bedauerns – zur Notwendigkeit einer Jugendpolitikfolgenforschung
Authors: Lips Anna , Schröer Wolfgang
Published: January 2025

Ausgehend von einem kurzen Abriss der Jugendpolitik wird ein Verständnis von Jugendpolitik als Politik für die Lebenslage Jugend (Lüders, 2018) hergeleitet. Auf der Grundlage dieses Verständnisses wird im Anschluss entlang der unterschiedlichen Politikebenen – ‚politics‘, ‚policies‘, ‚polity‘ (Bock, 2010) exemplarisch danach gefragt, wie Jugend – ‚politics‘ – inhaltlich als politisches Thema wahrgenommen wird, welche politischen Prozesse im Kontext von Jugend – ‚policies‘ – beobachtet werden können und über welche Akteur:innen und institutionellen Rahmungen – ‚polity‘ – Jugend während der COVID-19-Pandemie politisch reguliert wurde. Der vorliegende Artikel analysiert anhand dieses Dreiklangs, welche politischen Schwerpunktsetzungen sich während der Pandemie in Bezug auf die Lebenslage Jugend identifizieren lassen und reflektiert diese auf der Grundlage des Forschungsstandes, insbesondere aus der Perspektive junger Menschen. Abschließend wird argumentiert, dass eine systematische und datenbasierte Jugendpolitikfolgenforschung ein Desiderat in Deutschland darstellt, um die Reichweite jugendpolitischer Regulationen, Strategien und Diskurse einschätzen zu können. Dies wäre aber eine Bedingung, um wissenschaftliche Aussagen über die jugendpolitischen Konsequenzen der COVID-19-Pandemie treffen zu können.
Raus aus der Gruppe – wie sich Kinder in der Kindertagesstätte entziehen
Authors: Schlattmeier Franziska
Published: January 2025

Kinder sind in der Kita fast permanent in der Gruppenlogik organisiert und die Teilnahme an Aktivitäten ist häufig obligatorisch. Vor diesem Hintergrund des bindenden Charakters der Aktivitäten sowie der Perspektive, Kinder als Akteure zu sehen, wird im Folgenden der Frage nachgegangen, wie sich Kinder Gruppen(situationen) entziehen. Hierzu werden unterschiedliche Facetten aufgezeigt, wie sich Kinder räumlich, körperlich und kommunikativ entziehen. Diese Erkenntnisse reichern bisherige Überlegungen zur Agency von Kindern in der Kita an und können in Bezug auf Praktiken des Widerstandes oder des Zulassens diskutiert werden.
Prospects for application of biomarkers of intestinal permeability and inflammation in meconium to intestinal disease diagnosis in infants
Authors:   Samara State Medical University, Samara, Russian Federation, Fursova A.D. , Pechkurov D.V. ,   Samara State Medical University, Samara, Russian Federation, Kol'tsova N.S. ,   Samara State Medical University, Samara, Russian Federation, Zaplatnikov A.L. ,   Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation
Published: January 2025

The paper presents a review of literature data focused on a study of levels of laboratory inflammatory markers (i. e., lactoferrin, fecal calprotectin,
neutrophil gelatinase-associated lipocalin, etc.), as well as biomarkers of impaired permeability of intestinal wall (zonulin, alpha-1-antitrypsin)
and epithelial tight junctions (i. e., occludin) in meconium. An advantage of non-invasive diagnostic methods (including laboratory fecal tests)
used in neonatology is emphasized. Availability and non-invasiveness of a meconium test are highlighted. Potential practical application of a
laboratory meconium test to obtain additional data on an impact of various unfavorable factors on a fetus in an antenatal period is discussed.
The paper addresses a prospective application of a meconium test to predict a risk of health issues in a neonate in the postnatal period. Along
with this, special attention is given to a potential assay of biological markers of inflammation (i. e., calprotectin) and intestinal permeability
disorders (i. e., zonulin, occludin) in meconium to develop a screening of intestinal disease risk factors in neonates and infants. A need for
further scientific researches in this area is emphasized.
KEYWORDS: intestine, meconium, neonate, calprotectin, intestinal permeability, zonulin, occludin.
FOR CITATION: Fursova A.D., Pechkurov D.V., Kol'tsova N.S., Zaplatnikov A.L. Prospects for application of biomarkers of intestinal
permeability and inflammation in meconium to intestinal disease diagnosis in infants. Russian Journal of Woman and Child Health.
2024;7(4):330–333 (in Russ.). DOI: 10.32364/2618-8430-2024-7-4-6
COVID-19 and ARVI: probiotic therapy features in pre-COVID-19, COVID-19 and post-COVID-19 periods
Authors:   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Savenkova M.S. , Solovyova M.V. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Tkachenko N.I. ,   Pirogov Russian National Research Medical University, Moscow, Russian Federation, Abramova N.A. ,   Sectoral Clinical Diagnostic Center of the Gazprom PJSC, Moscow, Russian Federation, Kraseva G.N. ,   Sectoral Clinical Diagnostic Center of the Gazprom PJSC, Moscow, Russian Federation
Published: January 2025

Due to COVID-19-associated respiratory and gastrointestinal disorders leading to comprehensive management of post-COVID-19 conditions,
probiotics studies are of interest in the COVID-19 and the post-COVID-19 periods.
Aim: to review national and foreign studies focused on a role of probiotics in pre-COVID-19, COVID-19 and post-COVID-19 periods. The
emphasis is on studies combining gastrointestinal (GIT) disorders associated with acute respiratory infections (ARI) in pre-COVID-19,
COVID-19 and post-COVID-19 periods. It is especially noted that efficiency of probiotics can be discussed in relation to a specific strain(s)
only. Moreover, at this particular COVID-19 period a ‘'gut-lung axis-mediated immune responses'' theory in which a respiratory barrier was
likely to be recovered by an impact on intestinal microbiota, was common to explain probiotic effects. A drug product containing two probiotic
strains, Lactobacillus rhamnosus LGG® and Bifidobacterium BB-12® (≥109 CFU of living bacteria), along with other probiotics, demonstrated
good perspectives to manage respiratory disorders in the post-COVID-19 period.
KEYWORDS: probiotics, microbiota, influenza virus, rhinovirus, SARS-CoV-2 infection, diarrhea.
FOR CITATION: Savenkova M.S., Solovyova M.V., Tkachenko N.I., Abramova N.A., Kraseva G.N. COVID-19 and ARVI: probiotic therapy
features in pre-COVID-19, COVID-19 and post-COVID-19 periods. Russian Journal of Woman and Child Health. 2024;7(4):342–348 (in Russ.).
DOI: 10.32364/2618-8430-2024-7-4-8
Functional gastrointestinal disorders in infants: an emphasis on infant colic
Authors:   Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Russian Federation, Taranushenko T.Ye.
Published: January 2025

Functional gastrointestinal disorders are considered as a severe issue in pediatrics. The urgency of infant colic (IC) issue is determined by both
the leading clinical symptom complex and issues arising in an infant's environment and reducing the quality of life of parents and significant
others. Not coincidentally, according to Rome IV criteria for IC, a definition of IC includes not only prolonged crying and anxiety of an infant
for no clear reason, but also a carer's discomfort resulting in family stress, depression, and child abuse. The paper provides up-to-date
information on IC, as well as it addresses the most significant risk factors for intestinal dysfunction development, etiology and mechanisms of
IC development. Diagnosis and a list of the most likely conditions to be differentiated with infant colic are discussed. Management of IC infants
is described in a dedicated section of the paper. A comprehensive approach should prevent the further progression of intestinal disorders,
complication occurrence and, at the same time, work towards improved quality of life of both patients and their family members.
KEYWORDS: functional gastrointestinal disorders, children, infant colic, infant crying, phytopreparations, intestinal dysfunction.
FOR CITATION: Taranushenko T.Ye. Functional gastrointestinal disorders in infants: an emphasis on infant colic. Russian Journal of Woman
and Child Health. 2024;7(4):349–354 (in Russ.). DOI: 10.32364/2618-8430-2024-7-4-9
Is inadvertent rupture of amniotic membranes common?
Authors: Hijona Elósegui J.J. , Carballo García A.L. , Fernández Rísquez A.C. , Expósito Montes J.F. , Presa Loritea J.C.
Published: January 2025

Introduction: Premature rupture of membranes (PROM) is defined as that clinical situation in which there is a loss in the solution of continuity of amniotic membranes prior to the onset of labor. Of multifactorial etiology, its clinical importance lies in being responsible for a high rate of infectious complications, both maternal and fetoneonatal.
It is plausible that there are inadvertent cases of RPM, but to our knowledge, such a circumstance has not yet been studied. With the present investigation we intend to establish the rate of inadvertent RPM at the time of delivery in our environment.
Patients and methods: In order to respond to the proposed objective, a cross-sectional descriptive analysis of a sample of 228 patients in labor process was carried out, randomly selected and representative of the patients treated for this reason in our Center. In all of them, the presence of type 1 Insulin-like growth factor binding protein was determined in the birth canal, in the absence of signs and symptoms suggesting PROM.
Results: The prevalence of inadvertent PROM at the time of delivery is 2.63%.
Conclussions: The trascendent implications for the puerperal and perinatal development of an inadvertent PROM make it advisable to deepen the study of this complex entity.
LEVEL ACADEMIC BURNOUT IN FINAL LEVEL STUDENTS OF THE FACULTY OF MEDICINE MUSLIM UNIVERSITY OF INDONESIA
Authors: Ghassani Rivai Andi Fauzan , Mokhtar Shulhana , Harahap Muhammad Wirawan , Amir Suliati P , Aisyah Windy N.
Published: January 2025

Education is a primary need for a nation. As students, individuals are expected to be creative and independent. Many students experience pressure due to academic demands. This can cause fatigue or burnout syndrome, which is a condition where a person experiences emotional exhaustion, a tendency to depersonalize, and feelings of helplessness. This phenomenon is known as academic burnout. When students are under constant pressure, this can lead to burnout which is characterized by exhaustion, frustration, cynicism towards others, and a sense of uselessness. This study aims to determine the level of academic burnout in final year students at the Faculty of Medicine, Indonesian Muslim University. The design of this research is descriptive observational, where data collection is carried out over a certain period of time during the research. Research data was obtained from primary data using the School Burnout Inventory (SBI) questionnaire where the total sample for this study was 225 respondents. The results showed that 162 (72%) respondents experienced low levels of academic burnout, 35 (16%) experienced moderate levels of academic burnout, 27 (11%) did not experience academic burnout, and 1 (1%) respondent experienced high levels of academic burnout. Based on the research results, the personal inadequacy dimension has the highest average level compared to other dimensions.
POTENTIAL OF SAMBAS SIAM ORANGE (Citrus nobilis var. microcarpa) LEAVES ETANOL EXTRACT AGAINST Escherichia coli
Authors: Irvandy Muhammad Syifa , Zakiah Mistika , Asseggaf Syarifah Nurul Yanti Rizki Syahab , Mahyarudin Mahyarudin , Mardhia Mardhia
Published: January 2025

Escherichia coli has virulence factors and is able to avoid host defenses, and is resistant to antibiotics. Increasing resistance requires alternative therapies, including natural ingredients. The potential that comes from West Kalimantan is the Siamese orange (Citrus nobilis var. microcarpa). All parts of this plant contain secondary metabolites that can be utilized, for example the leaves. The compounds contained in secondary metabolites have antibacterial properties. This study was to determine the antibacterial potential of the ethanol extract of Siamese orange leaves on the growth of Escherichia coli bacteria. Method The orange leaves were extracted using 70% ethanol then continued with phytochemical analysis and antibacterial activity testing using the disc diffusion method. The results of the phytochemical analysis showed that the ethanol extract of Siamese orange leaves contained phenolics, alkaloids, saponins, flavonoids, and steroids. Antibacterial activity testing at all concentrations showed no inhibition zone. Conclusion The ethanol extract of Siamese orange leaves did not have antibacterial activity on the growth of Escherichia coli bacteria.
STERILE ENDOPHTHALMITIS FOLLOWING CATARACT SURGERY IN THE LEFT EYE: A RARE CASE REPORT OF TOXIC ANTERIOR SEGMENT SYNDROME (TASS)
Authors: Costrila Caroline , Faozan
Published: January 2025

Toxic anterior segment syndrome (TASS) is a complicated condition following eye surgery. TASS is sterile and can occur due to non-infectious toxic substances with various etiologies. A 55-year-old man diagnosed with oculi sinistra toxic anterior segment syndrome, oculi dextra astigmatism composite myopia and oculi dextra et sinistra presbyopia with pseudophakia that occurred after cataract surgery with phacoemulsion technique and administration of ciprofloxacin eye drops. Ciprofloxacin, an antibiotic, can cause ocular toxicity by depositing on the cornea surface. The precipitation is closely related to the PH of the tear film
Prompt Engineering for Conversational AI Systems: A Systematic Review of Techniques and Applications
Authors: Panneer Selvam Viswanathan
Published: January 2025

This article comprehensively analyzes prompt engineering techniques in conversational AI systems, focusing on their implementation and impact on large language model (LLM) performance. The article examines the fundamental principles of effective prompt design, including clarity, contextual framing, and instructional phrasing, while exploring advanced techniques such as prompt chaining, few-shot learning, and domain-specific adaptations. The article investigates role-based prompting strategies and parameter optimization methods, addressing critical challenges in bias mitigation and response consistency. The findings demonstrate that well-crafted prompts significantly enhance LLM output quality across various domains, including healthcare, finance, and education. The article also reveals emerging trends in automated prompt generation and multimodal applications, suggesting future directions for prompt engineering development. This article contributes to the growing knowledge in AI interaction optimization and provides practical guidelines for implementing effective prompt engineering strategies in conversational AI systems.
Implementation of Aggloromative Hierarchical Clustering Using Single Linkage
Authors: Dr. G. Vijaya Lakshmi
Published: January 2025

Classifying and grouping similar type of data objects in one segment is known as clustering. There are different types of techniques to create the clusters namely partitioning methods, hierarchical methods, density-based methods, and grid-based methods. . In this paper, we focus on agglomerative hierarchical techniques which is also known as bottom-up approach. In this approach the objects are successively form clusters into one until termination condition holds. In this paper, python we construct distance matrix by measuring the distance between the two data points. There after a dendrogram is prepared by providing a visual representation that helps to the find the optimal number of clusters.
Procjena razvoja prirodoslovne pismenosti poučavanjem Biologije i prijedlog alata za (samo)vrednovanje i unaprjeđenje takvog poučavanja
Authors: Meštović Ozrenka , Meštrović Jasenka , Labak Irena
Published: January 2025

Iako su predmetni kurikuli koji potiču razvoj prirodoslovne pismenosti u hrvatskom obrazovanju prisutni već pet godina, rezultati vanjskih vrednovanja ukazuju na nedovoljnu razvijenost ove pismenosti kod učenika. Cilj ovoga rada je utvrditi koliko se razvija prirodoslovna pismenost kod učenika 8. razreda tijekom poučavanja Biologije. Za potrebe istraživanja analiziran je i modificiran originalni obrazac za praćenje nastave (OZON obrazac) te su se pomoću njega analizirali video-zapisi nastavnih sati sedam učiteljica koje u osmom razredu predaju Biologiju. Rezultati analize video-zapisa ukazuju na nedovoljnu zastupljenost aktivnosti i poticaja kojim se razvija prirodoslovna pismenost. S obzirom da je prirodoslovna pismenost složen konstrukt koji obuhvaća različita znanja i vještine, poučavanje za njen razvoj zahtijeva različite poticaje za aktivan angažman učenika od uključivanja učenika u istraživanje i zaključivanje do samovrednovanja. Zbog toga je originalni obrazac uz predloženu modifikaciju dobar alat za (samo)vrednovanje poučavanja koje potiče prirodoslovno opismenjavanja učenika te koji usmjerava profesionalni razvoj učitelja.
Digital Da’wah in the Modern Era
Authors: Wina Sumiati  , Nawawi Taosyekh
Published: January 2025

The digitalisation of da’wah refers to the utilisation of online platforms such as Instagram, TikTok, YouTube, Facebook, and Twitter to disseminate Islamic teachings. This transition from traditional to digital da’wah is being embraced by three online Islamic communities: NU Garis Lucu, AISNU, and Pondok Sanad. The primary question this study addresses is: How do these online da’wah communities employ digital platforms to propagate Islamic teachings, and how do consumers of digital da’wah respond to these methods? The study aims to analyse the da’wah methods employed by these communities and to explore how consumers of digital da’wah engage with them, including their preferences and the platforms they favour. A mixed-methods approach, combining both qualitative and quantitative research, is employed. Qualitative data is gathered through interviews with community members and consumers of digital da’wah, alongside direct observations of the activities of the three communities. For the quantitative component, a survey of 100 respondents examines their reactions to digital da’wah. The findings reveal that NU Garis Lucu, AISNU, and Pondok Sanad adopt gentle, non-violent methods (Al-mauizah hasanah) and tailor their approaches to different contexts (Al-hikmah). The methods employed by these communities were generally well received by the respondents.
ІСТОРИЧНІ ТА СУЧАСНІ АСПЕКТИ ФУНКЦІОНУВАННЯ НАЦІОНАЛЬНОГО ПРИРОДНОГО ПАРКУ «СИНЕВИР» , ПРИРОДОХОРОННЕ І НАУКОВЕ ЗНАЧЕННЯ
Authors: Ярема Ю.М. , Нірода Т.М. , Нанинець М.В. , Субота Г.М.
Published: January 2025

В статті висвітлено історичні та сучасні аспекти розвитку національного природного парку «Синевир», його природоохоронна та науково-дослідна діяльність. Оптимізація ландшафтного різноманіття спрямованого на збереження унікальних еталонів природних комплексів і об’єктів. Функціональне зонування, що враховує регіональні, національні та міжнародні вимоги созологічного статусу природних екосистем.
Ключові слова: НПП «Синевир», ландшафти, функціональне зонування.

The article highlights the historical and modern aspects of the development of the Synevyr National Nature Park, its nature protection and scientific research activities. Optimization of landscape diversity aimed at preserving unique benchmarks of natural complexes and objects. Functional zoning that takes into account regional, national and international requirements of the sociological status of natural ecosystems.
Key words: NNP "Synevyr", landscapes, functional zoning.
МЕТЕОРОЛОГІЧНА ХАРАКТЕРИСТИКА СЕЗОНІВ РОКУ ПРИРОДНОГО ЗАПОВІДНИКА «РОЗТОЧЧЯ»
Authors: Скобало О.С. , Гребельна В.О.
Published: January 2025

У роботі проаналізовано зміни та особливості сезонів року, зокрема тривалості та кількості опадів, мінамльної, максимальної та середньодобової температури повітря тощо за період 1993-2023 рр. Відзначено збільшення тривалості літа та вегетаційного періоду та зменшення тривалості зими. Тривалість весни скорочується, характерними рисами сезону є низька вологість повітря, холодні ночі, теплі дні, невелика кількість опадів, що ускладнює роботу аграріїв. Середня тривалість осені зменшилася, і часто характеризується як більш посушлива.
Ключові слова: тривалість сезонів; середньодобова температура повітря; опади; аномальні явища.

Results of multi-year monitoring of the abiotic environment Roztochya Nature Reserve. The work analyzed the changes and features of the seasons, including duration and precipitation, temperature, etc., for the period 1993-2023. The increase in the duration of summer and the vegetation period, and the decrease in the duration of winter were noted. The duration of spring is decreasing, the characteristic features of the season are low air humidity, cold nights, warm days, and a small amount of precipitation, which complicates the work of farmers. The average duration of autumn has decreased, and often is characterized as drier.
Keywords: length of seasons; average daily air temperature; precipitation; abnormal phenomena.
СУЧАСНИЙ СТАН ФЛОРИ ТА ФАУНИ ПРИРОДНИХ ЕКОСИСТЕМ, ДОСЛІДЖЕННЯ РІДКІСНИХ ВИДІВ РОСЛИН, ТВАРИН І ОСЕЛИЩ НА ТЕРИТОРІЇ НПП ,,ВЕРХОВИНСЬКИЙ”
Authors: Прокопюк М.М.
Published: January 2025

Національний природний парк «Верховинський» є науково-дослідною установою загальнодержавного значення, входить до склада природно-заповідного фонду України і підпорядковується Міністерству екології та природних ресурсів України. В даному матеріалі розглянемо наукові дослідження на території НПП «Верховинський», що до збереження видів флори, фауни та природних серидовищ.
Ключові слова: флора; фауна; оселеща; фототека; праліси; Зелена книга України; Червона книга України.

Verkhovynskyi National Nature Park is a research institution of national significance, is part of the Nature Reserve Fund of Ukraine and is subordinate to the Ministry of Ecology and Natural Resources of Ukraine. In this material, we will consider scientific research on the territory of the "Verkhovynskyi" NPP, which is related to the preservation of species of flora, fauna and natural habitats.
Keywords: flora: fauna; settlements; photo library; primeval forests; Green Book of Ukraine; Red Book of Ukraine.
ВПЛИВ ПІДЛІСКУ НА ФОРМУВАННЯ ЖИВОГО НАДҐРУНТОВОГО ВКРИТТЯ У СОСНОВИХ ДЕРЕВОСТАНАХ ШЕПЕТІВСЬКОГО ПОЛІССЯ
Authors: Сасюк А.В. , Заїка В.К. , Павлюк В.В.
Published: January 2025

Досліджено особливості поширення підліскових видів та формування підліску і живого надґрунтового покриву в 56-90-річних соснових деревостанах Шепетівського Полісся. У них виявлено 10 підліскових видів та 51 вид судинних рослин і 7 видів мохів в складі живого надґрунтового вкриття з 36 родин. Проведено аналіз розподілу підліскових і трав’янистих видів за їх лісівничо-екологічними властивостями.
Ключові слова: соснові деревостани, підлісок, живе надґрунтове вкриття

It was studied a peculiarities of distribution of understory species and the formation of understory and vegetation cover in 56-90-years old pine stands at Shepetivske Polissia. In those stands we found 10 understory species, 51 herb species and 7 species of the mosses (as a part of the vegetation cover) from 36 families. An analysis of the distribution of understory and herbal species based on their silvicultural and ecological characteristics was carried out.
Key words: pine stands, understory, vegetation.
ВПРОВАДЖЕННЯ СИСТЕМИ SMART В КАРПАТСЬКОМУ БІОСФЕРНОМУ ЗАПОВІДНИКУ
Authors: Довганич В. Я. , Довганич Я. О.
Published: January 2025

Впровадження системи SMART в Карпатському біосферному заповіднику. У статті обговорюється сучасний інструмент для управління природоохоронними територіями – патрульно-моніторингова система SMART. Наводяться переваги системи. Розповідається про те як працює ця система в Карпатському біосферному заповіднику. Наведені деякі результати застосування в охороні та веденні моніторингу за флорою і фауною заповідника.
Ключові слова: патрулювання, моніторинг, охорона, база даних, експорт даних.

Implementation of the SMART system in the Carpathian Biosphere Reserve. The article discusses a modern tool for managing protected areas – the SMART patrol and monitoring system. The advantages of the system are given. It tells about how this system works in the Carpathian Biosphere Reserve. Some results of application in the protection and monitoring of the flora and fauna of the reserve are presented.
Keywords: patrolling, monitoring, protection, database, data export.
ВАЖЛИВІСТЬ НЕФОРМАЛЬНОЇ ЕКОЛОГІЧНОЇ ОСВІТИ НАСЕЛЕННЯ ДЛЯ УСПІШНОГО РОЗВИТКУ ЗАПОВІДНИХ ТЕРИТОРІЙ УКРАЇНИ
Authors: Насадюк П.П. , Мамчур З.І.
Published: January 2025

Обговорено роль громадської обізнаності в запобіганні поширенню чужорідних інвазивних видів (ІЧВ). Показано важливість залучення громадськості до заходів із збереження біорізноманіття на природоохоронних територіях. Ключову роль у цьому процесі може відіграти неформальна екологічна освіта, забезпечуючи відповідне навчання та обмін досвідом. Запропоновано конкретні заходи неформальної екологічної освіти громадян, які можуть стати ефективним засобом для виявлення, моніторингу, управління, контролю та викоріннення ІЧВ.
Ключові слова: чужорідні інвазивні види, методи боротьби, неформальна екологічна освіта, природоохоронні території.

The role of public awareness in preventing the spread of invasive alien species (IAS) is examined. The importance of public involvement in biodiversity conservation within protected areas is emphasized. Informal ecological education plays a crucial role in this process by offering relevant training and facilitating the sharing of experiences. Specific measures for informal ecological education are proposed as effective tools for detecting, monitoring, managing, controlling, and eradicating IAS.
Keywords: invasive alien species, control methods, informal ecological education, protected areas.
ВИКОРИСТАННЯ КАНАЛУ «ЛЕЛЕКА ГРИЦЬКО» В ЕКОЛОГО-ОСВІТНІЙ ДІЯЛЬНОСТІ НАЦІОНАЛЬНОГО ПРИРОДНОГО ПАРКУ «ПИРЯТИНСЬКИЙ»
Authors: Шпак А.В.
Published: January 2025

Використання ютуб каналу в еколого-освітній діяльності Національного природного парку «Пирятинський» дозволило залучити значно ширшу аудиторію різного віку до популяризації природоохоронних знань, ніж традиційні методи роботи.
Ключові слова: лелека білий, еколого-освітня діяльність, екологічні знання, природно-заповідний фонд, ютуб канал, Національний природний парк «Пирятинський».

The YouTube channel was used in the environmental and educational activities of the National nature park «Pyryatynskyi» Poltava region Ukraine to attract a much wider audience of all ages to the popularization of ecological knowledge than traditional methods.
Keywords: white stork, ecological and educational activities, ecological knowledge, nature reserve fund, YouTube channel, National natural park «Pyryatynskyi».
Instrumentos para identificar pacientes elegíveis à paliação na Atenção Primária à Saúde
Authors: Pinto Eduardo Salmito Soares , Viana Magda Rogéria Pereira
Published: January 2025

Introdução: As transformações sociais ocorridas nas últimas décadas desencadearam importantes mudanças demográficas e epidemiológicas, dentre elas: a ampliação do número de acometidos por doenças crônicas não transmissíveis. Neste sentido, os cuidados em fim de vida tornam-se cada vez mais essenciais. Objetivo: Analisar os instrumentos de avaliação existentes para identificação de pacientes elegíveis aos cuidados paliativos na atenção primária à saúde. Métodos: Trata-se de uma revisão integrativa da literatura, realizada entre o período de fevereiro a maio de 2024, nas bases de dados da Literatura Latino Americana e do Caribe de Informação em Ciências da Saúde (LILACS) via Biblioteca Virtual em Saúde – BVS, da Scientific Electronic Library Online (SciELO), Índice Bibliográfico Español en Ciencias de la Salud (IBECS), SciVerse Scopus, Cumulative Index à Literatura de Enfermagem e Saúde (CINAHL), Web of sciencee e US National Library of Medicine (PubMED), utilizando-se os operadores booleanos and e e or em junção com os descritores. Os DeCS utilizados foram: cuidados paliativos; avaliação de programas e instrumentos de pesquisa; identificação de pacientes; e atenção primária à saúde. Resultados: A pesquisa identificou 158 artigos nas plataformas supracitadas. Destes, foram removidos 2 artigos por duplicidade. Após a leitura preliminar dos estudos e aplicação dos critérios de inclusão e exclusão, foram pré-selecionados 30 artigos, dos quais 21 não responderam aos objetivos. Assim, a amostra final para análise foi composta por 09 estudos. Discussão: O SPICT e o NECPAL são ferramentas que identificam pacientes com necessidades de cuidados paliativos com base em indicadores de saúde em declínio. O SPICT, desenvolvido no Reino Unido, utiliza sinais como internações não planejadas, perda de peso e sintomas persistentes para detectar deterioração em pacientes com doenças avançadas. Já o NECPAL, criado na Espanha, foca em uma avaliação rápida e objetiva da necessidade de cuidados paliativos, incorporando dimensões como declínio psicológico e cognitivo. Estudos internacionais destacam a eficácia dessas ferramentas na Atenção Primária, melhorando a qualidade de vida dos pacientes e reduzindo intervenções excessivas e custos de saúde. Conclusão: Os estudos sobre o tema abordado são limitados. No entanto, o aprimoramento e a divulgação desses instrumentos, torna viável a sua aplicabilidade na assistência básica, possibilitando a integralidade do cuidado ao paciente.