bluuebunny/crossref_metadata_2025 huggingface dataset:
Personnel development under digital economy conditions
Authors: Yedynak V. Yu , Kovtun N. S , Pasichnyk T. O , Kakhovych Yu. O , Kakhovych O. O
Published: May 2024

Purpose. This article aims to improve organizational, methodological, and practical approaches to a comprehensive assessment of the personnel development system in the digital economy, which will provide the basis for further development of specific mechanisms and tools for personnel development depending on the level of such development. Methodology. To achieve this goal, a whole range of both general scientific and special methods of scientific knowledge were used, namely abstract-logical methods, induction and deduction to study and summarize the existing theoretical and methodological foundations of personnel functioning and development in digital economy, generalization, comparison, index method to study the level of development of digital transformations and digital education of personnel in Ukraine, and graphical method to present the results of the study. Findings. While studying the theoretical and methodological foundations of personnel functioning and development in digital economy, it was found that despite the inevitability of the transition to digital economy and the importance of preparing personnel to work under new conditions, fundamental and analytical research is virtually absent. The existing studies only focus on the importance of digital transformation processes and the need for personnel development, but no specific mechanisms are proposed. The authors make an attempt to assess the level of personnel development based on the methods applied in Ukraine and the European Union, analyze the level of digital transformation and the level of digital education development across the regions of Ukraine, and compare the level of digital literacy of Ukraine’s personnel among the main age groups as well as with the corresponding indicators in the European Union. Originality. The results obtained in the course of the study have not been previously highlighted by domestic scientists and form a comprehensive system for assessing personnel development in the digital economy, which will allow them to be used in the future to apply certain tools for acquiring digital competences by personnel, based on the identified level. Practical value. The results of the study can be used by government agencies in terms of formulating state policy on the implementation of a digital economy and with regard to state plans on the formation of digital literacy of the population as well as by business entities in the process of selecting and developing their personnel.
Entre respostas digitais e saberes experienciais: o ChatGPT e a educação em perspectiva crítica
Authors: De Oliveira Barbosa Roberta , Leite Taveira Flávio Augusto , Peralta Deise Aparecida
Published: May 2024

Os avanços digitais transformam a educação ampliando o acesso a recursos online, e geram reflexões sobre seu impacto na sociedade contemporânea. O uso crescente das Inteligências Artificiais (IA), como o ChatGPT, que na educação traz eficiência, todavia incorre em dilemas éticos. Este artigo discute até que ponto essa ferramenta pode substituir a memória e a experiência humana, por meio da análise de entrevistas idênticas feitas com uma professora humana e o ChatGPT, usando oito perguntas estruturadas para comparação. A análise das respostas, feita com o software Iramuteq, identifica diferenças na distribuição lexical e no foco temático. Os resultados mostram que o ChatGPT não substitui a experiência humana, evidenciando diferenças na linguagem e no foco temático entre a professora humana e a IA. Esse estudo enfatiza a necessidade de considerar criticamente a relação entre seres humanos e tecnologia na pesquisa qualitativa e destaca a importância de uma abordagem ética no uso dessas ferramentas.
AN EVALUATION OF THE POWER SUPPORT INTERNET INFRASTRUCTURE OF MAKASSAR CITY IN TELEMEDICINE FRAME
Authors: Muhammad Figur , Achmad Andani , Adnan Adnan , Mubarak Abdul , Muis Abdul
Published: May 2024

This research aims to find the quality of the internet in Makassar City. It uses a 10 Mbps service from Indihome to support telemedicine. The study is a case study of sending raw MRI image data to the AWS cloud. The research uses a virtual server from the AWS cloud. It stores raw MRI image data. The data will be sent via the FTP client FileZilla. The tests were carried out eight times. They used the quality of service standard formula from TIPHON. The results come from 8 tests. In the tests, MRI image data was sent to the AWS cloud. The results show that the average throughput value was 4.53 Mbps with an index of 4. This result is excellent. Packet loss is low at 0.01% with an index of 4, which is very good. The delay is 1.7 ms with an index of 3, which is good. The jitter is 1.69 ms with an index of 3, which is good. The quality of service test results are based on TIPHON standards. They show that sending Raw MRI image data to the AWS cloud at 10 Mbps from Indihome in Makassar City is good.
EVALUATING HYBRID NEURAL NETWORK ARCHITECTURES FOR PREDICTING SLEEP DISORDERS FROM STRUCTURED DATA
Authors: Airlangga Gregorius
Published: May 2024

The accurate diagnosis of sleep disorders is crucial for effective treatment and management, yet current methods often rely on subjective assessments and are not always reliable. This research examines the efficacy of various neural network architectures, including dense networks, convolutional neural networks (CNNs), recurrent neural networks (RNNs), and innovative hybrid models, in predicting sleep disorders from structured health data. Our study focuses on comparing the performance of these models using metrics such as accuracy, precision, recall, and F1 score across a dataset comprising 400 individuals with detailed sleep and lifestyle data. Our findings demonstrate that while traditional models like dense networks and CNNs for structured data yield robust results, hybrid models, particularly the CNN-Transformer, significantly outperform others. This model effectively integrates convolutional layers with Transformer’s attention mechanisms, excelling in handling complex data interactions and providing superior predictive accuracy with an F1 score and accuracy reaching as high as 0.91. Conversely, RNN models, designed to capture temporal data dependencies, showed less efficacy, underscoring the importance of model selection aligned with data characteristics. This suggests that for datasets not exhibiting strong temporal features, models leveraging spatial relationships or advanced attention mechanisms are more suitable. This study not only advances our understanding of neural network applications in medical diagnostics but also highlights the potential of hybrid models in enhancing diagnostic accuracy. These insights could lead to significant improvements in the early detection and treatment of sleep disorders, thereby enhancing patient outcomes and contributing to the broader field of medical informatics.
Pengaruh Desentralisasi Fiskal, Investasi dan Tingkat Partisipasi Angkatan Kerja (TPAK) Terhadap Pertumbuhan Ekonomi
Authors: Utomo Widhea Indira , Tambunan Maria R.U.D
Published: May 2024

This Research aims to determine the effect of fiscal decentralization, investment and labor force participation rate on the economic growth of districts or cities in one of the largest provinces on java. This analysis consists of several variables including Investment, labor force participation rate and fiscal decentralization that uses income and expenditure indicators. This study also uses Gross Regional Domestic Product (GRDP) indicators at constant prices for economic growth with total of observations are 140 data from 35 district or cities in Central Java Province for the 2017-2020 period with complete data ownership. The data that used in this study were collected and processed using multiple linear analysis methods to determine simultaneously and particially between fiscal decentralization, investment, labor force participation and economic growth. The research results show that Fiscal Decentralization and Investment have proven to significantly increase economic growth in the Province of Central Java. However, the Labor Force Participation Rate (TPAK) in Central Java Province does not have a significant effect on the economic growth. Regional Income and Regional Expenditure that are well managed will have a positive impact on the economic growth of each region. This can be optimized by taking advantage of current technological developments and demographic bonuses where there is a balance in overcoming good governance, then this will create productivity which can have an impact on economic that more effective and efficient.
Pobreza menstrual: Aspectos socioeconômicos e culturais
Authors: Melo Vitória Farias de , Oliveira Sheila Soares , Lucena Roberta Araújo de , Nobre Flávia Milene de Souza , Santos Yasmyn Menezes de Jesus , Cardoso Wellington Campos , Silva Raul Santos , Cardoso Lorena Correia , Prado Carla Azevedo , Batista Priscilla Daisy Cardoso , Carvalho Márcia Neves de
Published: May 2024

Introdução: A pobreza menstrual é um fenômeno complexo, transdisciplinar e multidimensional, enfrentado por meninas e mulheres em todo o mundo devido à falta de acesso a recursos, escassez de políticas públicas com infraestrutura adequada e desinformação para que tenham capacidade de realizar o manejo correto da higiene menstrual. Considerando que a pobreza menstrual é reconhecida como um problema de saúde pública em todo o mundo, este estudo objetiva abordar a sua problemática, identificando e analisando suas implicações socioeconômicas e culturais. Metodologia: Realizou-se uma revisão narrativa da literatura, utilizando-se as bases de dados LILACS, PubMed, SciELO e GOOGLE ACADÊMICO. Resultados: A pobreza menstrual, além de afetar a saúde física e psíquica de várias pessoas, ainda conserva e intensifica a desigualdade entre gêneros. As meninas deixam de frequentar as escolas quando há falta de meios para cuidar da própria menstruação, como infraestrutura inadequada e pouca disponibilidade de produtos voltados para a higiene, submetendo-as a situações que ridicularizam e menosprezam. Essa realidade repleta de paradigmas advém de um histórico em que o sangramento visível era considerado sinônimo de sujeira, impureza e vergonha. A problemática que envolve a pobreza menstrual é mundial, pois percebe-se que bilhões de mulheres ainda não têm acesso efetivo aos meios de higiene básica e pessoal. Conclusão: A educação menstrual é crucial para enfrentar a pobreza menstrual, abordando saúde sexual e reprodutiva. É vital iniciar o diálogo sem estigmas antes da primeira menstruação, incorporando saberes populares. Políticas públicas devem garantir uma vivência digna do período menstrual, reduzindo o absenteísmo escolar.
A influência das mídias sociais sobre a obsessão por uma alimentação saudável em adolescentes
Authors: Eugenio Katryne de Azevedo , Dutra Lavínia Yorrane , Sousa Bruna Luíza Mano , Santana Isabela da Costa , Oliveira Lívia Ester , Bicalho Juliana Mara Flores
Published: May 2024

Introdução: O termo Ortorexia Nervosa é definido como a obsessão e fixação em comer alimentos saudáveis, a ponto de se tornar patológico. O perfil dos indivíduos vulneráveis inclui pessoas meticulosas, organizadas e com exacerbada necessidade de autocuidado ou proteção. Esse grupo pode incluir mulheres, adolescentes, pessoas adeptas de modismos alimentares e atletas. Destaca-se a preocupação com os adolescentes, visto que nessa fase há intensas alterações no organismo e na vida e questões relacionadas à alimentação merecem atenção. Objetivo: Identificar fatores relacionados à Ortorexia em adolescentes. Métodos: Foi realizada uma revisão narrativa de literatura entre agosto e outubro do ano de 2023 com busca por artigos nas bases de dados: Scientific Eletronic Library Online (SciELO), Google Acadêmico, US National Library of Medicine (MEDLINE/PubMed), Biblioteca Virtual de Saúde (BVS) e ScienceDirect. Como critérios de inclusão foram selecionados artigos originais e que referiam à temática, disponíveis gratuitamente na íntegra, nos idiomas inglês, espanhol e português. Discussão: Nos estudos foram identificados alguns grupos vulneráveis, dentre eles destacam-se os adolescentes. Além disso, foi apontado que as mídias sociais têm grande impacto na percepção que os adolescentes têm sobre seus próprios corpos, sucedendo a uma excessiva alimentação saudável desencadeando sintomas de ON. Conclusão: As mídias sociais podem intensificar os sintomas depressivos e de transtornos, especialmente na adolescência. A dificuldade associada à Ortorexia é diferenciar o indíviduo que prioriza hábitos alimentares saudáveis daquele que apresenta comportamento obsessivo. Os estudos ainda são escassos sobre Ortorexia Nervosa e por isso, há necessidade de mais pesquisas sobre o tema.
Uso de termômetro infravermelho como alternativa para aferição termométrica em cães
Authors: Soares Guilherme Marques , Santana Carolina Maria de , Almeida Raísa Vianna de , Peixoto Fernando Cunha
Published: May 2024

A avaliação termométrica é importantíssima na rotina da clínica médica de pequenos animais e muitas vezes a contenção para que a aferição, que é feita com termômetro de coluna rígida de mercúrio ou termômetro digital, seja precisa e segura pode levar o animal ao estresse. Na tentativa de minimizar esse estressor, neste estudo propôs-se usar o termômetro de infravermelho, que ficou muito popular durante a pandemia de COVID-19 para triagem de humanos com febre para acesso de espaços públicos coletivos. Este projeto visou aferir a temperatura corporal dos cães com dois métodos distintos e comparar a eficiência dessas metodologias, para tal comparou-se o resultado da aferição tradicional via retal com termômetro digital com a aferição da temperatura externa do ânus e do conduto auditivo de 100 cães na rotina clínica de uma clínica veterinária do município do Rio de Janeiro. Foi possível estimar que em média a temperatura no conduto auditivo é 1,2ºC menor do que a temperatura retal e no anis 1,9º C menor do que a retal. Porém, o coeficiente de correlação foi baixo (<0,4) nas duas abordagens. Pode-se concluir que o uso de termômetro infravermelho não se mostrou uma alternativa confiável para substituir a termometria tradicional.
Antibody responses and B cell immunity after pertussis booster vaccination
Authors:   , Versteegen Pauline
Published: May 2024

Pertussis, commonly known as whooping cough, is caused by the Bordetella pertussis bacterium and is a respiratory tract infection with potentially severe complications, especially in unvaccinated infants. Vaccination against pertussis began in the 1950s, leading to a significant decline in its incidence. However, in recent decades, there has been a global resurgence of pertussis cases despite high vaccination rates. This resurgence is partly attributed to the transition from whole cell pertussis (wP) to acellular pertussis (aP) vaccines. Research presented in this thesis also revealed an increase in the pertussis infection prevalence in the Netherlands based on serosurveillance studies. This increase was most pronounced among adolescents but also observed in school-aged children and middle-aged adults.

Subsequently, this thesis investigated antibody development in children and adults following a booster vaccination with an aP vaccine and describes the B-cell response post-vaccination. Robust pertussis-specific IgG antibody responses were observed in children, adolescents, and younger and older adults, with good neutralizing capacity. IgA antibody production post booster vaccination was more pronounced in older adults compared to younger individuals and contributed to serum neutralizing capacity. B-cell responses also expanded after booster vaccination, although memory responses were less pronounced in older adults compared to younger individuals.

Since pertussis often presents mild or atypical in vaccinated children and adolescents, revaccination of these groups may not contribute much to their health while experiencing a pertussis infection can even broaden their immunity against pertussis. However, for older adults, who are more likely to experience complications from pertussis infection, booster vaccination could be considered. This is also true for other (medical) risk groups. Future research on new vaccines not only preventing disease symptoms but also transmission is crucial for better pertussis control. Continued investigation to immunological correlates of protection against pertussis remains relevant for this purpose.
Improvising Infrastructure
Authors:   , Protschky Andrea Rita
Published: May 2024

The thesis explores how unhoused Berliners living in public spaces or using temporary emergency shelters use or replace infrastructures for water, energy, communication, and mobility. It is based on a qualitative empirical study conducted between September 2020 and April 2023. As provision and use of infrastructures are commonly tied to accommodations and most services need to be paid for, access for unhoused urbanites is impeded. The study shows how unhoused persons achieve limited access via assistance services, at the homes of friends or family, in public spaces (e.g., public toilets, in cafés), or relying on portable or improvised solutions. As infrastructures form a basis for social practices, limited infrastructure access can be understood as social exclusion. The contribution explores this concept, identifying social interdependency, material participation, and participation in rights and norms as core aspects of social inclusions/exclusions.
Based on work by Marx, Bourdieu, and authors in their wake, the study examines these aspects within infrastructure practices, focusing on different actors’ spatial and temporal strategies, material objects, and the body as a basis for and shaped by practices. It illustrates how infrastructure access is enabled and limited by conflicting spatial and temporal strategies of unhoused persons and other actors, including the implementation of statutory regulations in specific spaces, temporal limitation of access to services, or covert practices of unhoused persons. As a result of curtailed access, unhoused persons often experience grave effects on their bodies, while their marked bodies and material objects reinforce and naturalize their social exclusions, e.g., when persons with disabilities cannot use services due to physical barriers or ‘dirty’ or ‘malodorous’ persons are banned from using public transport based on the provider’s terms of use. In summary, the study demonstrates that all identified ways of infrastructure access are marked by social exclusions, while access options are differentiated by aspects like levels of social interdependency, material comfort, or legal exclusion. The text ends with a discussion of how to achieve infrastructure access for unhoused persons, arguing for housing against homelessness and limited infrastructure access, the democratization and decommodification of basic infrastructures, and political alliances between different social groups to achieve this change.
Literasi Inklusi Keuangan Digital Berbasis Ekonomi Syariah bagi Nelayan Ikan Depik (Endemik) Danau Laut Tawar
Authors: Mellyan Mellyan , Junaidi Junaidi , Diana Sari
Published: May 2024

The Depik Fishermen (Rasbora Tawarensis/Lepsotoma) in Lake Laut Tawar, Central Aceh, mostly still employ traditional systems in the process of selling Depik Fish. Introduction to digital marketing is needed for Depik fishermen to market this endemic fish to the public. The aim of this community service was to increase the income of Depik fishermen in Lake Laut Tawar and to explain various digital marketing strategies suitable for increasing sales of Depik fishermen in Lake Laut Tawar. The community service method used Participatory Action Research (PAR) with interview instruments, observations, seminars, and training to obtain desired results. The results of the community service successfully introduced digital marketing systems to Depik fishermen by creating Instagram accounts, opening shops on Shopee and Online Stores. Additionally, it introduced online Sharia financial platforms besides Banks, such as Investree, Ammana – Online Sharia Loans, Online P2P Lending Loans, BSalam, and others. There were also investment platforms like Amartha.com, specializing in SMEs, Bibit with its flagship product mutual funds, and crowdfunding systems like Tani Fund. However, there were some issues such as decreasing Depik catch results due to the use of floating cages, resorts along the lake, and the presence of Hoe fishermen. As for Depik fish catches, in the first quarter of 2021 it amounted to 12.602 tons, then increased in the second quarter to 18 tons, then decreased in the third quarter to 1.444 tons and significantly decreased again in the sixth quarter to 0.031 tons.
Internalisasi Furudul Ainiyah dalam Meningkatkan Kemampuan Membaca Al-Quran Santri Madrasah Diniyah Raudlatul Muta’allimin di Kraksaan Probolinggo
Authors: Yakin Ainul
Published: May 2024

This community service program aims to determine the internalization method of Furudlul Ainiyah (FA), the impact, supporting and inhibiting factors of FA internalization in Madrasah Diniyah Raudlatul Muta'allimin students. This program used an educational and participatory approach to achieve Al-Quran learning targets. This program results showed that: 1). FA internalization was focused on learning the Al-Quran using the method of listening, reading, introducing makharijul letters and writing hijaiyah letters using the Iqra' ang Tartila textbook. 2). The impact of FA internalization could introduce students to hijaiyah letters, makharijul letters and how to read the Al-Quran more effectively. The santri were not only able to read, but also memorize and write. 3). Supporting factors for FA internalization were qualified companions, limited classes and the enthusiasm of students. Meanwhile, the obstacles were inadequate learning facilities, lack of discipline of mentors and students in learning.
Pendampingan Inovasi dan Pemasaran Melalui Digital Marketing UMKM Tape Ketan Hitam di Desa Nguling Pasuruan
Authors: Yusuf Wiwin Fachrudin , Sulhan M. , Aziziyah Nur , Syarifah Nadyatus , Ulinnuha Muhammad Johar , Abas Abas , Sari Ardilla Khusliana , Andriyani Kristie , Mayang Mayang , Eryan Muhammad Rifqi
Published: May 2024

Community service for black sticky rice tape MSMEs in Nguling Village, Nguling District, Pasuruan Regency aims to provide assistance in innovating products and marketing digitally. The implementation method for this activity uses the ABCD (Asset based community development) method, the steps in implementation include five steps, namely discovery (discover), dream (dream), design (plan), define (determine), destiny (do). The result of community service in this activity is that MSME actors can understand the importance of product innovation and digital marketing and change traditional behavior to modern ones. MSME actors can also apply the results of assistance to their products. As for the implementation of this service, MSME actors receive direct training and assistance regarding product innovation and digital marketing from resource persons or practitioners who are professionals in their fields. Ultimately, all parties hope that this impact will take place in a sustainable manner to achieve the mutually expected goals.
Implementasi Modul Water Quality Meter pada Komunitas Petani Udang Vaname Jawa Timur
Authors: Nurmaida Firnanda Pristiana , Gunawan Agus Indra , Ariwibowo Teguh Hady , Ariyanto Ferry , Sanaba Utari , Habibulloh Muhamad Aldino , Tambunan Orlando Pratama , Kamaluddin Muhammad Wafiq
Published: May 2024

Vannamei shrimp is one of the leading commodities in fisheries aquaculture, due to its competitive price and the ability to be mass-produced with high stocking densities. Many coastal communities in East Java capitalize on this opportunity by engaging in vannamei shrimp cultivation. However, most shrimp farmers still measure pond water quality using conventional methods and record water quality parameters on paper, which is highly inefficient. With this issue in mind, the author sought to engage in community service by inviting representatives from the East Java vannamei shrimp farming community. The method involved delivering lectures and interactive discussions with shrimp farmers to understand their perceptions and insights regarding pond water quality, followed by the handover of modules, and subsequently evaluating the modules' usage by the shrimp farmers. As a result of this community service, we introduced a tool to assist traditional shrimp pond farmers in monitoring water quality, in the form of a "Water Quality Meter" module integrated with a website accessible via smartphones and laptops. The "Water Quality Meter" module was designed with a system to portable monitor pond water quality using Internet of Things (IoT) technology, where data obtained by microcontrollers is transmitted to a database to determine the quality value of pond water. Evaluation results indicate that farmers can use the module effectively, and data collected on the website shows that pond water quality for the farmers remains within normal ranges. Shrimp farmers directly benefit from using the module, as the shrimp pond monitoring process becomes more practical and accurate.
Pelatihan Pembinaan Penulisan Karya Ilmiah dan Esai bagi Guru SMA/SMK/MA dalam Upaya Meningkatkan Literasi Siswa
Authors: Kusmiatun Ari , Mawaidi Mawaidi , Triono Eko , Rahayu Dwi Hanti
Published: May 2024

Writing training at the high school level in Yogyakarta has been going well. However, there are many problems in its implementation due to the lack of competitive motivation among teachers or school institutions. This lack of motivation causes teachers' self-confidence to decrease and students are not optimal in the process of increasing literacy. This article is the output of writing training in schools for SMA/SMK/MA teachers in an effort to increase student literacy which can create motivation for students to think critically and achieve. By using a participatory action research approach, this community (PKM) seeks to overcome demotivation regarding the ability to write scientific papers and essays at the high school level in Yogyakarta which is caused by many students who are not interested and are less competitive in the field of writing. The results of PKM that have been achieved are increased motivation of teachers and students’ writing abilities, especially in the context of writing and presentation competitions. This PKM has also succeeded in creating collaboration between institutions, both between schools and between private institutions, which will be managed in the future in the context of developing writing and increasing student literacy.
Eco-Friendly Media: Assistance in Developing Educational Props from Waste Materials in Probolinggo City
Authors: Manshur Umar , Rozi Fathor , Saleha Latifatus , Sholihah Chodijatus
Published: May 2024

This community engagement was driven by the limitations of resources and adequate facilities within the early childhood education environment. The restricted or monotonous use of educational props, coupled with financial limitations within the institution, constrains the variety and creativity in the learning process. Additionally, the lack of understanding regarding the potential use of waste materials as educational props hinders more engaging teaching innovations. This community engagement aimed to introduce the creation of educational props using waste materials available within the school environment by providing engaging learning stimuli, thereby making the content delivered by teachers more effective and efficient. The approach used in this community engagement was Asset-based Community Development (ABCD). The approach enables the community to build upon existing strengths without depending on external assistance. This approach began by identifying the assets possessed by the community, which were then utilized to develop the educational institution. The outcomes of this engagement indicated some important points. First, teachers, in early childhood educational institutions in Probolinggo City, understood appropriate stimuli for the growth and development of students, demonstrating competence in pedagogic skills as one of the essential competencies for teachers. Secondly, teachers in these institutions could utilize waste materials to create Educational Play Tools (EPT) through identifying recyclable waste, training, and practical application in crafting these tools. Thirdly, teachers were capable of harnessing local potential previously untapped, which could be used to support learning activities by turning them into Educational Play Tools (EPT).
Ecoliteracy Sampah Pembalut Sekali Pakai pada Santri Pondok Pesantren Annuqayah Guluk-Guluk Sumenep
Authors: Halim Abdul , Nabilla Dila Fitri , Paisun Paisun , Hasanah Lutfi Uswatun
Published: May 2024

The modern community's alarming waste issue is single-use sanitary pads. Every day, 26 tons of sanitary pad waste are generated in Indonesia. Over a year, each person is estimated to produce 300 sanitary pad wastes, totaling around 11,000 wastes throughout their lifetime. In Islamic boarding schools (pesantren), this sanitary pad waste problem also needs immediate attention. At Annuqayah Islamic Boarding School, with a total of 3,468 female students, there is a potential of producing 1,040,400 single-use sanitary pad wastes annually. Hence, reducing sanitary pad waste is crucial. This community service activity aims to reduce single-use sanitary pad waste through minimizing their usage. The method employed in this activity was through the Participatory Action Research (PAR) approach, where students were encouraged to be more environmentally conscious and gradually abandon the use of single-use sanitary pads. The strategies involved in the activity include conducting Focus Group Discussions (FGD), Environmental Film Discussions, Environmental Seminars, training on making environmentally friendly sanitary pads, establishing an environmentally friendly sanitary pad production house, FGDs on policy formulation regarding the implementation of environmentally friendly sanitary pads, and mentoring on the implementation of environmentally friendly sanitary pads in the pesantren. The results of the community service show that this activity successfully increased students' awareness and concern for the environment, enhanced students' knowledge about single-use sanitary pads, provided life skills training on making environmentally friendly sanitary pads, established regulations prohibiting the use of single-use sanitary pads in the pesantren, and implemented the use of environmentally friendly sanitary pads at Annuqayah Islamic Boarding School
Castle of the Pomeranian Dukes in Szczecin — reconstruction of a renaissance residence after 1945 and contemporary transformation of a cultural centre
Authors: Fiuk Piotr
Published: May 2024

After 1945, the representative residence of the Pomeranian Dukes was reconstructed from the period of the building's splendour - the late Gothic south wing and the Renaissance architecture of the wings encompassing the courtyards - based on a comprehensive analysis of archival cartographic and iconographic material. Prior to developing the designs for the reconstruction of the castle with the reconstruction of the artistically valuable fragments, multifaceted inventory and scientific research was carried out, and successive versions of the functional layout were developed, adapted to the changing requirements and decisions of the authorities and institutions supervising the restoration of the historic appearance of the most important building in Western Pomerania. Szczecin was the unofficial capital of the Duchy of Pomerania, the extinction of the Gryfit dynasty took place in 1637. The plans for the rebuilding of the castle did not envisage reflecting the successive stages of rebuilding the ducal residence that occurred after the loss of independence of Pomerania and after the administration of Szczecin was taken over by the Kingdoms of Sweden (mid 17th century) and Prussia (early 18th century). During the period when Szczecin belonged to the Scandinavian dynasty, plans were made to significantly rebuild the castle. The Prussian authorities undertook extensive construction work to transform the former ducal residence into a building adapted, among other things, to the needs of the new administration and garrison (the dilapidated Renaissance forms were replaced with mansard roofs and schematic Baroque decorations, characteristic of the Friedrich period). Fragments of the grandiose decorations were demolished, radically transforming the architecture of the castle from the period of the Pomeranian Duchy reflecting the tradition of the Slavic Griffin dynasty.
A new spectrophotometric method for sensing promethazine hydrochloride in its pharmaceutical formulation and in biological fluids using copper nanoparticles (CuNPs)
Authors: Atiyah Muqdad I. , Al-Samarrai Shatha Y. , Al-Hayawi Anas Y.
Published: May 2024

A new, simple, and sensitive spectroscopic method has been developed for the determination of PMH in its pure form, in its pharmaceutical formulation, and in biological fluids (blood and urine) spectrophotometrically using copper nanoparticles (CuNPs) synthesized by the green method as a colorimetric detector without the use of chemical reagents. This method was characterized by being easy, sensitive, inexpensive, and environmentally friendly. A colored product (PMH-CuNPs) was formed. The absorbance was measured at the wavelength of 641.4 nm, and the linear range of (20–280) μg/ml, and it was found that the value of the correlation coefficient was (0.9983), the detection limit was (0.39) μg/ml, the quantitative limit was (1.18) µg/ml, and the molar absorption coefficient was (1315.69) L/mol. cm and Sandell significance were (0.2439) µg/cm2, the average value of the percent recovery was 100.4%. The method was successfully applied to estimate Promethazine. HCL (PMH) in its pharmaceutical formulation and in biological fluids, and the characteristics of the colored product (PMH-CuNPs) were diagnosed. By measuring with several techniques, the average diameter was 73.54 nm in AFM technique, and the average crystal size through the XRD technique was 58 nm. SEM was measured, and the complex particles appeared in a spherical or semi-spherical shape, with an average size of 71.89, 82.04, and 79.25. FTIR was measured, and the functional groups were determined.
Overview and Progress of GNSS Anti-multipath Antenna Designs
Authors: Dong Jianming , Hua Qiang
Published: May 2024

This article provides a comprehensive review of recent applications of GNSS anti-multipath antenna. Emphasis is placed on the role of anti-multipath antenna in GNSS. A brief summary of the current anti-multipath antenna in satellite-based navigation systems is provided and also the GNSS anti-multipath antenna plays a key role is emphasised, which will help in getting a better understanding of the requirements on the various performance parameters of a GNSS antenna. In addition, we review GNSS anti-multipath antenna design strategies and specific design examples that highlight the application of various types of GNSS anti-multipath antenna. Ultimately, this articles seeks to demonstrate the value of GNSS anti-multipath antenna design insights for antenna engineering and look toward promising new research directions for GNSS antenna research.
Modelling the impact of inter-electrode spacing on nitrate removal using Response Surface Methodology (RSM)
Authors: Khan Mohammad Amir , Al-Hayawi Anas Y.
Published: May 2024

Nitrate contamination in water poses a significant concern for environmental engineers, as it has substantial and direct impacts on water quality, the economy, and public health. Consequently, managing nitrate levels in water sources ranks among the top priorities for water authorities. Currently, various treatment methods, including biological treatments and adsorption, are employed to eliminate nitrate from water or wastewater. A substantial body of literature exists focused on the application of electrocoagulation (EC) for nitrate removal from solutions. This method is favoured for its environmentally friendly attributes and ability to swiftly and cost-effectively remove pollutants. In this study, the EC method was employed to eliminate nitrate from water under varying inter-electrode spacing (I-ES) conditions ranging from 4 to 10 mm and different treatment durations (TD) spanning 5 to 55 minutes. The effects of I-ES and TD on nitrate removal were optimised using Response Surface Methodology (RSM). The study's results demonstrated that the most effective nitrate removal, reaching 91.3%, occurred at an I-ES of 4 mm and a TD of 50 minutes. The agreement between the experimentally observed and predicted removal rates was notably high, with an R2 value of 0.973.
The Influence of Shepherd Leadership Based on 1 Timothy 3:1-6 on the Spiritual Growth of Congregants in the Gereja Kristen Kudus Indonesia (GKKI) in Jabodetabek
Authors: Sunardi Philipus
Published: May 2024

This research highlights the significance of leadership in the spiritual growth of the congregation within the context of the Indonesian Christian Holy Church (GKKI) in Jabodetabek. The correlation analysis results indicate that Shepherd Leadership holds a substantial relationship with Spiritual Growth (correlation coefficient = 0.693, Sig < 0.1). These findings demonstrate that the comprehension and execution of vision and mission by a spiritual leader have a considerable impact on enhancing the quantity of faith among the congregation. This study suggests that spiritual leaders need to have a thorough understanding of their roles and responsibilities in order to lead effectively, mitigate conflicts, and shepherd competently. Furthermore, the research findings shed light on challenges faced by the congregation, such as difficulties in spiritual growth. This research makes a significant contribution to understanding the dynamics of spiritual leadership within the GKKI context in Jabodetabek.
The Repeated Word "Yarad" In the Book of Jonah: Points, Pattern, And Purpose
Authors: Prabowo Paulus Dimas
Published: May 2024

The Book of Jonah contains the word 'yarad' four times, which constitutes one of the recurring motifs in the text. Its usage is often interpreted as indicative of multidimensional degradation and is even associated with foreshadowing Christ's redemptive work. However, a critical question arises: What was the author of the Book of Jonah attempting to underscore through the repeated inclusion of the word 'yarad'? This study aims to delve into the occurrences of 'yarad' in the Book of Jonah through stylistic analysis to discern patterns, thereby elucidating the author's intent in employing these repetitions throughout the narrative. The methodology employed is stylistic analysis, with particular attention paid to the repetitive element. Consequently, discernible patterns emerge in 1:3b, 1:3c, 1:5b, and 2:6a, which exhibit a tendency towards diminishment yet encompass contrasts and pivotal moments. Consequently, it becomes evident that the author of the Book of Jonah strategically employs the word 'yarad' four times to accentuate contrasts, degradation, and pivotal shifts.
Pengembangan Software SCADA Dinamis Teknik Otomasi (SCATO) dengan Multi Koneksi Dan Protokol Modbus
Authors: Putra Nata Hatan Maurisga , Khumaidi Agus , Rahmat M. Basuki
Published: May 2024

Didalam dunia industri, teknologi mengalami perkembangan yang signifikan. Dalam menyikapi perkembangan tersebut telah diklasifikasikan dalam revolusi industri, yang ditandai dengan adanya perkembangan skala besar pada aspek kehidupan manusia. Selain itu, sistem akuisisi data sangat dibutuhkan guna menunjang perkembangan Industri 4.0. Kebutuhan akan software yang mudah serta dapat digunakan dengan berbagai koneksi dan menggunakan banyak protokol menjadi sangat tinggi. Hal ini dikarenakan meningkatnya kebutuhan sistem akuisisi data di industi, dengan lokasi yang berjauhan namun dapat pengawasan dan juga pengendalian. Selain itu dibutuhkan perangkat lunak (software) yang memudahkan pengguna dalam menampilkan data dan dapat terinegrasi dengan terintegrasi dengan perangkat hardware. Oleh karena itu penulis memiliki sebuah inovasi untuk merancang perangkat lunak berbasis GUI, guna mengoptimasikan software Scada yang dapat melakukan komunikasi dengan protokol Modbus guna dapat melakukan proses memonitoring maupun controlling secara real time. Disini peneliti menggunakan protokol komunikasi Modbus TCP/IP dan Modbus RTU. Pada penelitian ini protokol komunikasi yang telah dirancang dapat bekerja dengan baik dan memiliki akurasi pengiriman dan pembacaan data sebesar 100% dengan kecepatan pembacaan data rata-rata sebesar 0,50 detik untuk komunikasi Modbus RTU dan 0.58 detik untuk komunikasi Modbus TCP/IP.
Screening and construction of nanobodies against human CD93 using phage libraries and study of their antiangiogenic effects
Authors: Miao Hui , Wu Yiling , Ouyang Hao , Zhang Peiwen , Zheng Wenyun , Ma Xingyuan
Published: May 2024

Background

Cluster of Differentiation 93 (CD93) plays an important role in angiogenesis and is considered an important target for inhibiting tumor angiogenesis, but there are currently no therapeutic antibodies against CD93 in the clinic. Thus, we describe the screening of novel nanobodies (Nbs) targeting human CD93 from a phage library of shark-derived Nbs.

Methods

Screening and enrichment of phage libraries by enzyme-linked immunosorbent assay (ELISA). Anti-CD93 Nbs were purified by expression in E. coli. The binding affinity of anti-CD93 Nbs NC81/NC89 for CD93 was examined by flow cytometry (FC) and ELISA. The thermal stability of NC81/NC89 was examined by ELISA and CD spectroscopy. Afterward, the anti-angiogenic ability of NC81/NC89 was examined by MTT, wound healing assay, and tube formation assay. The expression level of VE-cadherin (VE-Ca) and CD93 was detected by Western Blot (WB). The binding sites and binding forms of NC81/NC89 to CD93 were analyzed by molecular docking.

Results

The anti-CD93 Nbs were screened in a phage library, expressed in E. coli, and purified to >95% purity. The results of FC and ELISA showed that NC81/NC89 have binding ability to human umbilical vein endothelial cells (HUVECs). The results of ELISA and CD spectroscopy showed that NC81/NC89 retained the ability to bind CD93 at 80°C and that the secondary structure remained stable. In vitro, the results showed that NC81 and NC89 significantly inhibited the proliferation and migration of human umbilical vein endothelial cells (HUVECs) as well as tube formation on Matrigel. Western Blot showed that NC81 and NC89 also inhibited the expression of VE-Ca thereby increasing vascular permeability. It was found during molecular docking that the CDR regions of NC81 and NC89 could be attached to CD93 by strong hydrogen bonds and salt bridges, and the binding sites were different.

Conclusion

We have successfully isolated NC81 and NC89, which bind CD93, and both Nbs significantly inhibit angiogenesis and increase vascular permeability. These results suggest that NC81 and NC89 have potential clinical applications in angiogenesis-related therapies.
Biomechanical comparisons of F.E.R.I. techniques with different type of intramedullary screws fixation for Jones fractures
Authors: Su Kuo-Chih , Yen Yu-Chun , Wang Chun-Hsiang , Wang Yi-Lun , Wang Shun-Ping
Published: May 2024

Introduction: Jones fractures frequently fail to unite, and adequate fixation stability is crucial. This study aimed to elucidate the biomechanical stability of various intramedullary screw fixation constructs.

Methods: Jones fracture model over the proximal 5th metatarsal of artificial bone was created in all specimens. Six groups were divided based on varied screw constructs with different screw lengths, either 30 or 40 mm, including cannulated screws—C30 and C40 groups, one high-resistance suture combined with intramedullary cannulated screws (F.E.R.I. technique)—CF30 and CF40 groups, and second-generation headless compression screws (SG-HCS) —HL30 and HL40 groups. Mechanical testing was conducted sequentially, and the maximal force (N) and stiffness (N/mm) of all constructs were recorded.

Results: The maximal force (N) at 1.0 mm downward displacement in C30, C40, CF30, CF40, HL30, and HL40 groups were 0.56 ± 0.02, 0.49 ± 0.02, 0.65 ± 0.02, 0.49 ± 0.01, 0.68 ± 0.02, and 0.73 ± 0.02, respectively, and the stiffness (N/mm) in subgroups were 0.49 ± 0.01, 0.43 ± 0.01, 0.67 ± 0.01, 0.42 ± 0.01, 0.61 ± 0.01, and 0.58 ± 0.02, respectively. SG-HCS subgroups exhibited greater maximal force and stiffness than conventional cannulated screws. Screws of 30 mm in length demonstrated better stability than all 40 mm-length screws in each subgroup. In C30 fixation, the stiffness and maximum force endured increased by 1.16 and 1.12 times, respectively, compared with the C40 fixation method. There were no significant differences between CF30 and SG-HCS groups. Only the F.E.R.I technique combined with the 4.5 mm cannulated screw of 30 mm in length increased the biomechanical stability for Jones fractures.

Discussion: These biomechanical findings help clinicians decide on better screw fixation options for greater stability in Jones fractures, especially when large-diameter screws are limited in use. However, this biomechanical testing of intramedullary screw fixation on Jones fracture model lacks clinical validation and no comparisons to extramedullary plate fixations. Moving forward, additional clinical and biomechanical research is necessary to validate our findings.
Modeling airway persistent infection of Moraxella catarrhalis and nontypeable Haemophilus influenzae by using human in vitro models
Authors: Ariolli Andrea , Canè Martina , Di Fede Martina , Tavarini Simona , Taddei Anna Rita , Buno Kevin Pete , Delany Isabel , Rossi Paccani Silvia , Pezzicoli Alfredo
Published: May 2024

Non-typeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis (Mcat) are two common respiratory tract pathogens often associated with acute exacerbations in Chronic Obstructive Pulmonary Disease (COPD) as well as with otitis media (OM) in children. Although there is evidence that these pathogens can adopt persistence mechanisms such as biofilm formation, the precise means through which they contribute to disease severity and chronicity remains incompletely understood, posing challenges for their effective eradication. The identification of potential vaccine candidates frequently entails the characterization of the host-pathogen interplay in vitro even though this approach is limited by the fact that conventional models do not permit long term bacterial infections. In the present work, by using air-liquid-interface (ALI) human airway in vitro models, we aimed to recreate COPD-related persistent bacterial infections. In particular, we explored an alternative use of the ALI system consisting in the assembly of an inverted epithelium grown on the basal part of a transwell membrane with the aim to enable the functionality of natural defense mechanisms such as mucociliary clearance and cellular extrusion that are usually hampered during conventional ALI infection experiments. The inversion of the epithelium did not affect tissue differentiation and considerably delayed NTHi or Mcat infection progression, allowing one to monitor host-pathogen interactions for up to three weeks. Notably, the use of these models, coupled with confocal and transmission electron microscopy, revealed unique features associated with NTHi and Mcat infection, highlighting persistence strategies including the formation of intracellular bacterial communities (IBCs) and surface-associated biofilm-like structures. Overall, this study demonstrates the possibility to perform long term host-pathogen investigations in vitro with the aim to define persistence mechanisms adopted by respiratory pathogens and individuate potential new vaccine targets.