bluuebunny/crossref_metadata_2025 huggingface dataset:
Non-Nutritive Suck Assessment Tool Development to Characterize Sucking Patterns in Infant with Various Hunger Levels
Authors: Saputra Casmika , Inati Iin
Published: December 2023

Sucking abilities are critical in early infant development, and the patterns of non-nutritive suck (NNS) have been found to potentially predict neurodevelopmental issues in the future. Proper NNS assessments are essential to ensure valid conclusions. Previous studies have shown that the level of infant arousal significantly affects NNS patterns. However, the author did not find any studies that observed the influence of infant hunger levels on NNS patterns. Therefore, this study aimed to develop an NNS assessment tool to characterize NNS patterns in infants with various hunger levels. The NNS assessment was conducted using a pressure transducer connected to a pacifier. The results showed that the level of hunger significantly affected the intra-burst frequency and the sucking pressure. The more hungry the infant, the more frequent the intra-burst frequency became, while the sucking pressure tended to decrease. The intra-burst frequency of infant sucking was 2.3, 2.46, and 2.5 Hz on average for a relative hunger index of 0.67, 0.83, and 1.0, respectively. The NNS pressure of infant sucking was 6.31, 4.51, and 2.62 kPa on average for a relative hunger index of 0.67, 0.83, and 1.0, respectively. This study's results suggest that during NNS assessments, the measurement time should consider the next feeding schedule for the infant.
Perancangan dan Simulasi Sensor Volume Zat Cair berbasis Metamaterial Rektangular
Authors: Syahputra Romi Fadli , Aisah Nurul , Ginting Delovita , Yana Debi , Husna Ropiqotul , Fitrya Neneng , Iwantono Iwantono , Saktioto Saktioto
Published: December 2023

Pengukuran volume zat cair yang sensitif dapat dicapai menggunakan alat ukur atau sensor. Akan tetapi sensor volume zat cair tidak banyak mengembangkan, padahal pengukuran volume berdampak langsuang pada  nilai ekonomis, keberhasilan penelitian ilmiah,  dan kemanjuran dosis obat. Penelitian yang telah dilakukan hanya sebatas pada pengukuran pada kenaikan permukaan zat cair  dalam kenaikan tandon. menggunakan sensor fotodioda. Metamaterial telah banyak dikembangakan sebagai sistem sensor yang sensitif karena berbasis gelombang elektromagnetik, namun belum spesifik mengkajinya sebagai sensor volume zat cair. Tujuan penelitian ini adalah untuk merancang dan menyimulasikan penggunaan sensor metamaterial yang sensitif dalam pengukuran volume zat cair.  Sensor didesain dengan prinsip split ring resonator berbentuk rektangular (SRR-R) yang terdiri  dari cincin logam tembaga dan substrat FR4-Epoxy. Sensor SRR-R disimulasikan pada rentang frekuensi 350-850 MHz untuk mendeteksi perubahan volume zat cair (aquades, air tawar dan etanol) dari 5 - 44 ml. Hasil simulasi menunjukan terjadinya pergeseran frekuensi resonan spektrum S21 yang  jelas untuk masing-masing zat cair. Pergeseraan frekuensi resonan untuk sampel aquades terjadi pada frekuensi 403 – 527 MHz, air tawar 403 – 528 MHz, dan etanol 60 – 783 MHz. Distribusi medan E dan medan H menunjukan nilai maksimum sebesar 18662 V.  dan 43771 A. . Karakteristik kurva linier terjadi dalam rentang volume 12-44 ml untuk semua sampel zat cair. Sensor metamaterial SRR-R berhasil disimulasikan untuk mendeteksi perubahan volume zat cair dengan sensitivitas pengukuran aquades -1.3999 MHz/ml, air tawar -2.6833 MHz/ml, adan etanol -3.5685 MHz/ml.
Network Analysis of Differential Expression of ANLN and Its Interacting Proteins in Esophageal Squamous Cell Carcinoma
Authors:   Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou 515041, China, Sun Hong , Cao Yufei ,   Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou 515041, China, Wu Bingli ,   Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou 515041, China, Tong Beibei ,   Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou 515041, China, Zou Huayan ,   Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou 515041, China, Xu Liyan ,   Key Laboratory of Molecular Biology in High Cancer Incidence Coastal Chao Shan Area of Guangdong Higher Education Institutes, Shantou University Medical College, Shantou 515041, China, Li Enmin ,   Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou 515041, China
Published: December 2023

Anillin (ANLN) is an actin binding protein, which was originally extracted from Drosophila melanogaster embryos. As a key regulatory factor in cytokinesis, ANLN is highly expressed in various tumors, leading to abnormal cell division and promoting the proliferation, migration, and invasion of cancer cells. At present, the role and regulatory mechanism of ANLN in human Esophageal Squamous Cell Carcinoma (ESCC) are not fully understood. The purpose of this study is to construct a Protein-Protein Interaction Network (PPIN) to reveal the characteristics of ANLN and its interacting proteins, by the integration of their expression in ESCC. The differentially expressed ANLN and its interacting proteins in ESCC were identified from our previous RNA-seq data. By constructing a specific PPI network, it was found that many differentially expressed genes/proteins may interact with ANLN. Multiple enrichment pathways of ANLN and its differentially expressed genes were explained by functional enrichment analysis, Gene Ontology (GO) analysis and KEGG pathway analysis. In addition, it is revealed that ANLN, ECT2, ACADM and PPP1R9A play an important role in the occurrence and development of ESCC, and they are proposed as new prognostic factors for ESCC. These bioinformatics analyses provide a comprehensive perspective for the role of ANLN in ESCC.
Comparison of Microbiological Results of Superficial Swab versus Deep Tissue Biopsy in Diabetic Foot Infections: A Prospective Observational Study from North India
Authors:   Indira Gandhi Medical College, Shimla, India., Kumar Rajesh , Mokta Jatinder K ,   Indira Gandhi Medical College, Shimla, India., Mir Bilal A ,   Indira Gandhi Medical College, Shimla, India., Mokta Kiran ,   Indira Gandhi Medical College, Shimla, India., Majeed Tahir ,   Indira Gandhi Medical College, Shimla, India.
Published: December 2023

Introduction: Diabetes mellitus is the leading cause of nontraumatic lower extremity amputation worldwide. Risk of developing a foot ulcer in diabetic patients has increased to 12-25% during their lifetime. Inappropriate sampling technique leading to contaminated samples is a well-known threat among patients of diabetic foot. In this study we compared two microbiological sampling techniques, superficial swabbing and deep tissue biopsy for identification of pathogens. Material and Methods: It was a prospective observational cross-sectional study. Diabetic foot was defined as per standard guidelines. Careful and meticulous examination of diabetic foot ulcer was done. Two specimens were collected from each wound. The first specimen was a wound swab collected by using Levine technique; another was taken via punch biopsy from the ulcer base. It was a deep tissue sample of 4 mm size. Results: A total of 120 diabetic patients with diabetic foot infection were included in this study. In swab culture 80.83% patients had mono microbial growth, 15% had polymicrobial and 4.10% had no growth. In deep tissue culture 87.50% had mono microbial growth, 2.50% had poly microbial and 10% were sterile. Staphylococcus aureus was most common isolate followed by E. coli. It was observed that though monomicrobial growth was most common in both the types of samples but was higher in deep tissue biopsy than in superficial swab samples. Conclusion: The isolation of microorganism via deep tissue sampling in diabetic foot ulcer patients is more reliable compared to superficial swab samples and a better guide to antibiotic therapy.
Intergenerational Associations of Adverse Childhood Experiences and Adolescent Engagement in High-Risk Behaviors
Authors:   Department of Pediatrics, Quillen College of Medicine, East Tennessee State University, USA, SA Ray , AM Yoders ,   Department of Pediatrics, Quillen College of Medicine, East Tennessee State University, USA, MA Quinn ,   Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, USA, K Phalen ,   College of Arts and Sciences, East Tennessee State University, USA, MD Cabral ,   Department of Pediatrics and Adolescent Medicine, Western Michigan University Homer Stryker M.D. School of Medicine, USA, M Shrestha ,   Department of Pediatrics and Adolescent Medicine, Western Michigan University Homer Stryker M.D. School of Medicine, USA, DL Wood ,   Department of Pediatrics, Quillen College of Medicine, East Tennessee State University, USA
Published: December 2023

Purpose: While the association between Adverse Childhood Experiences (ACEs) and negative health outcomes in adulthood is well established, very few studies have examined the cumulative impact of ACEs across generations (intergenerational ACEs – caregiver and youth) on health outcomes in adolescence. The purpose of this study is to examine whether intergenerational ACEs are associated with an increased likelihood of participation by youth in high-risk behaviors including tobacco use, vaping, alcohol use, engagement in sexual activity, or result in higher rates of affective disorders such as depression. Methods: 234 caregiver-youth dyads were recruited via a convenience sample from pediatric clinics at East Tennessee State University and Western Michigan University Homer Stryker M.D. School of Medicine. Participant dyads completed a survey assessing both caregiver and youth ACEs, youth depression, and youth participation in high-risk behaviors. Caregiver-youth dyads were sorted into an ACEs matrix with the following groups: Low Caregiver-Low Youth ACEs (LC-LY), Low Caregiver-High Youth ACEs (LC-HY), High Caregiver-Low Youth ACEs (HC-LY), and High Caregiver-High Youth ACEs (HC-HY). Results: HC-HY dyads were 11.4 times more likely to report moderate to severe depression compared to LC-LY dyads (p<0.01). HC-HY dyads were 4.5, 3.3, and 7.5 times more likely to have youth participate in alcohol use (p<0.05), vaping (p<0.05), and sexual activity (p<0.01), respectively, compared to LC-LY dyads. Conclusions: Intergenerational ACEs exposure was related to greater youth engagement in high-risk behaviors and risk of depression. Assessing both caregiver and youth ACEs would better identify youth at risk for alcohol use, vaping, sexual debut, and depression.
The Inevitable
Authors:   Department of Family Medicine, University of Ottawa, On, Canada, N Guérard-Poirier
Published: December 2023

It is both a truth rooted in the most powerful laws of evolution. An inevitable experience tinged by cultural perceptions as well as the heaviness of the past of being. It is a presence that seeps into our lives, a sneaky thought, a promise of mortality, which sooner or later will land on our shoulders. A message that this privilege, which is life, is coming to an end. Sometimes it touches us like the lightness of a feather, sometimes it is an inexorable suffering that makes even the strongest delirious to finally die away peacefully; like the fire of a candle, dissipating forever in the infinite and unknown mist of darkness. Death is about facing your own frailty. In our Western society where the most powerful reign; the deadline is perceived as a failure. However, there is nothing more natural. The ancient Egyptians believed that bodily preservation was essential so that the spirit of the being could travel to immortality. Death was an artistic medium expressed through mummies. According to the more scientific school of thought where all energy is transformed, this lets us imagine the possible perpetuity and the infallible significance of our passage on earth.
Ovarian Torsion in 17-year-old Nulligravida with Polycystic Ovarian Disease
Authors:   Department of Obstetrics and Gynaecological Nursing, Smt. Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Medical Sciences, India, Sathawane Himanshi , Pannase Krutika ,   Department of Obstetrics and Gynaecological Nursing, Smt. Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Medical Sciences, India, Ronghe Vaishnavi ,   Department of Obstetrics and Gynaecological Nursing, Smt. Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Medical Sciences, India, Modak Anushri ,   Department of Obstetrics and Gynaecological Nursing, Smt. Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Medical Sciences, India, Dhore Archana ,   Department of Obstetrics and Gynaecological Nursing, Smt. Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Medical Sciences, India, Bansod Spandan ,   Department of Obstetrics and Gynaecological Nursing, Smt. Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Medical Sciences, India, Kantode Vaishnavi ,   Department of Medical Surgical Nursing, Smt. Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Medical Sciences, India, Nakhale Abhas ,   Department of Community Health Nursing, Smt. Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Medical Sciences, India, Thool Bali ,   Department of Obstetrics and Gynaecological Nursing, Smt. Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Medical Sciences, India
Published: December 2023

Ovarian torsion is defined as the complete or partial rotation of the adnexal supporting organ in the presence of ischemia. To maintain the health of the ovaries and fallopian tubes and prevent severe morbidity, early diagnosis is essential. Ovarian torsion emerges in 2 percent to 15 percent of patients who have a procedure of adnexal mass. Acute pelvic pain that suddenly starts is the most typical sign of ovarian torsion, followed by nausea and vomiting. Ultrasonography revealed that left ovary is enlarged measures 5.16×4.62×3.99cm volume 49.8ml with hemorrhagic cyst of size 4×3cm. The recovery of macroscopically nonviable ovaries is feasible with laparoscopic conservative management and ovary untwisting. To confirm the result, prolonged follow-up is necessary.
Early Identification of Type 2 Diabetes Using Glycated Haemoglobin in Primary Care Medical Offices as a Proof of Feasibility in Austria
Authors:   Division Nephrology, 4th Department Medicine, Klinikum Wels-Grieskirchen, Wels, Austria, Prischl Friedrich C , Rebhandl Erwin ,   Diabetes Study Group, Austrian Society of Family Medicine (ÖGAM), Haslach, Austria, Zehetmayer Sonja ,   Section for Medical Statistics, University of Medicine, Vienna, Austria
Published: December 2023

Numerous studies have been carried out on determination of glycated haemoglobin to diagnose type 2 diabetes (T2D), among them the manuscript by Selvin et al [1]. They have led the American Diabetes Association (ADA) to recommend haemoglobin A1c (HbA1c) measurements to identify patients having diabetes in their 2010 position statement with a cut off of =6.5 % [2]. Nevertheless, there is some controversial discussion whether HbA1c should be the gold standard for diagnosis of T2D instead of fasting glucose or oral glucose tolerance testing with various arguments in favour of HbA1c [3].
What are the Best Drugs and Combinations in Afro-Descendant Hypertensive Patients?
Authors:   Full Professor of Cardiology, Collegiate Medicine/DCSAU - State University of Santa Cruz (UESC), Full Professor of Cardiology at the University of Technology and Science (UniFTC) – Campos de Jequié, Brazil, Dinamarco Nelson , Fernandes FAHA Isabella ,   Medical Student at the State University of Santa Cruz (UESC), Brazil, Plavnik Frida L ,   Physician of the Arterial Hypertension Group at the Hospital Alemão Oswaldo Cruz, São Paulo, Collaborating Researcher - InCor São Paulo, Brazil
Published: December 2023

Hypertension in African descendants occurs early, with high rates of cardiovascular events compared to Caucasians. In addition, genetic influence, low levels of plasma renin activity, greater sensitivity to salt, low sodium secretion, and other mechanisms are involved and discussed in this article. For pharmacological treatment, several studies were evaluated, such as CREOLE, ALLHAT, CARDIA, JHS, REGARDS, AASK, ACCOMPLISH, review articles and meta-analyzes and some guidelines, such as European, American, Brazilian to compare treatment indication. Several pharmacological classes, such as calcium channel blockers, Β-blockers, renin angiotensin system inhibitors, aldosterone and diuretics were included in present review in order to compare utilization and indication for Afro-descendant hypertensive patients. We concluded that several relevant points should be considered in the pharmacological treatment of African descendants that include pathophysiological characteristics, early development of lesions in target organs, in addition to higher rates of cardiovascular and renal events. In addition to lifestyle changes, improved nutrition, combined treatment, probably as a first-line treatment, should be considered as an approach, and the drugs used should aim at blood pressure control and inhibition of the inflammatory process, which results in worse outcomes. It is important to highlight that the representativeness of the Afro-descendant population was unsatisfactory for a robust conclusion. in this population, we can infer from the initial pharmacological treatment the use of thiazide-like diuretics, or dihydropyridine calcium channel blocker should be considered, although the institution of fixed combinations with angiotensin enzyme conversion inhibitors or angiotensin receptor blockers are important in the protection of target organs that occurs earlier and more seriously.
Discovery of red-shifting mutations in firefly luciferase using high-throughput biochemistry
Authors: Colee Clair M. , Oberlag Nicole M. , Simon Marcell , Chapman Owen S. , Flanagan Lyndsey C. , Reid-McLaughlin Edison S. , Gewing-Mullins Jordan A. , Maiche Synaida , Patel Devi F. , Cavalcanti Andre R.O. , Leconte Aaron M.
Published: December 2023

The Photinus pyralis luciferase (FLuc) has proven a valuable tool for bioluminescence imaging, but much of the light emitted from the native enzyme is absorbed by endogenous biomolecules. Thus, luciferases displaying red-shifted emission enable higher resolution during deep-tissue imaging. A robust model of how protein structure determines emission color would greatly aid the engineering of red-shifted mutants, but no consensus has been reached to date. In this work, we apply deep mutational scanning to systematically assess twenty functionally important amino acid positions on FLuc for red-shifting mutations, predicting that an unbiased approach would enable novel contributions to this debate. We report dozens of red-shifting mutations as a result, a large majority of which have not been previously identified. Further characterization revealed that mutations L286V and T352M, in particular, cause pure red emission with much of the light being >600 nm. The red-shifting mutations identified by this high-throughput approach provide strong biochemical evidence for the multiple-emitter mechanism of color determination, and point to the importance of a water network in the enzyme binding pocket for altering the emitter ratio. This work provides a broadly applicable mutational data set tying FLuc structure to emission color that informs our mechanistic understanding of emission color determination and should facilitate the further engineering of improved probes for deep-tissue imaging.
Ring Opening Metathesis Polymerization (ROMP) of the Dewar Isomer of 1,2-Azaborinine, a B-N Isostere of Benzene
Authors: Lin Huina , Yang Xinyu , Liu Shih-Yuan , Jaekle Frieder
Published: December 2023

The successful polymerization of the Dewar isomer of an azaborinine heterocycle is reported. Controlled ring-opening metathesis polymerization was accomplished with Grubbs and Hoveya-Grubbs 2nd generation catalysts (G2, HG2), as well as a Z-selective Ru catalyst (HGM2001). The structure of the polymers containing 4-membered B-N heterocycles was verified by GPC, multinuclear and 2D NMR. Differences in regiochemistry of polymers derived from G2/HG2 versus the Z-selective catalyst HGM2001 were substantiated by 2D NOESY, FT-IR and Raman analyses. The incorporation of B-N heterocycles into these polymer structures is promising as a route to functional polymers that contain polar side groups.
Kinds of Pregeometries of Acyclic Theories
Authors:   Novosibirsk State Technical University, Malyshev S. B.
Published: December 2023

The article is devoted to the description of types of pregeometries with an algebraic closure operator for acyclic theories. In these theories we describe conditions of violation of the exchange property for a pregeometry. Taking into account these conditions, we introduce new concepts that do not rely on the exchange property: 𝑎- pregeometry, 𝑎-modularity, etc. The dependence conditions for an 𝑎-modular and 𝑎- locally finite 𝑎-pregeometry on the number of non-isomorphic trees and special points are established. Sufficient conditions of dependence for a 𝑎-local finite 𝑎-pregeometry on the vertices of the 𝑎-type are established, too.
On the Local Coordination of Fuzzy Valuations
Authors:   Novosibirsk State Technical University, Yakhyaeva G. E.
Published: December 2023

The paper is devoted to the model-theoretic formalization of the semantic model of the object domain. The article discusses the concept of a fuzzy model, which is a model where the truth function exhibits properties of a fuzzy measure. We demonstrate that a fuzzy model is a generalization of the concept of fuzzification of a precedent (semantic) model to include a countable number of precedents. In practice, it is common to have partial expert knowledge about the set of events in the object domain, making it difficult to immediately describe the fuzzy model. Additionally, since expert valuations are subjective, they may be incorrect and inconsistent with any fuzzy model. In the article, we introduce the concepts of coordinated and locally coordinated valuation of a set of sentences, and provide proofs for interval theorems and an analogue of the compactness theorem.
On Some Problems of Trajectory Beam Program Control. Part I
Authors:   St. Petersburg University, Ovsyannikov D. A. , Kotina E. D. ,   St. Petersburg University
Published: December 2023

This paper deals with problems of program control of a trajectory beam. We investigate formulations that arise when considering problems of charged particle beams control, as well as, for example, in image processing. In applied problems, it is often necessary to investigate the problem of the gravity center control of some set or changing the density distribution of particles according to some given one. The functionals proposed in the paper can be effectively used for the velocity field constructing in various image processing, in particular, medical diagnostic images. In this paper, the problem of constructing a velocity field is considered as a control and optimization problem, and, unlike the previous works of the authors, macroparameters characterizing the objects under study are used in optimization. In the article, variations of the studied functionals are obtained and the necessary optimality conditions are given.
Pontryagin’s Maximum Principle and Indirect Descent Method for Optimal Impulsive Control of Nonlocal Transport Equation
Authors:   Matrosov Institute for System Dynamics and Control Theory of SB RAS, Staritsyn M. V. , Pogodaev N. I. ,   Matrosov Institute for System Dynamics and Control Theory of SB RAS, Goncharova E. V. ,   Matrosov Institute for System Dynamics and Control Theory of SB RAS
Published: December 2023

We study a singular problem of optimal control of a nonlocal transport equation in the space of probability measures, in which the structure of the drivng vector field with respect to the control variable is somewhat equivalent to the affine one, while the set of controls is norm-unbounded and constrained in the integral sense only. We show that the problem at hand admits an impulse-trajectory relaxation in terms of discontinuous time reparameterization. This relaxation provides a correct statement of the variational problem in the class of control inputs constrained in both pointwise and integral senses. For the relaxed problem, we derive a new form of the Pontryagin’s maximum principle (PMP) with a separate adjoint system of linear balance laws on the space of signed measures. In contrast to the canonical formulation of the PMP in terms of the Hamiltonian equation on the cotangent bundle of the state space, our form allows one to formulate an indirect descent method for optimal impulsive control analogous to classical gradient descent. We expose a version of this method, namely, an algorithm of the steepest descent with an internal line search of the Lagrange multiplier associated with the integral bound on control. The algorithm is proven to monotonically converge to a PMP-extremal up to a subsequence.
On an Approach to Finding Sums of Multiple Numerical Series
Authors:   Siberian Federal University, Kuzovatov V. I. , Myshkina E. K. ,   Siberian Federal University, Bushkova A. S. ,   Siberian Federal University
Published: December 2023

An approach to calculating sums of some types of multiple numerical series is presented. This approach is based on using the formula for the resultant of a polynomial (or an entire function with a finite number of zeros) and an entire function obtained earlier by A.M. Kytmanov and E.K. Myshkina. This formula does not require values of the roots of the functions under study and is a combinatorial expression. By calculating the resultant of a polynomial and an entire function in two different ways, it is possible to obtain a relation for multiple numerical series. For the second way to find the resultant, we use the product of one function at the roots of another. In this article, the sums of some types of multiple numerical series that were previously absent in known reference books are found. They are expressed in terms of well-known special functions such as the Bessel function. This approach to calculating the sums of multiple numerical series differs significantly from the method based on the use of residue integrals associated with a system of equations. The relevance of this problem is determined by the fact that in applied problems, for example, in the equations of chemical kinetics, there are functions and systems of equations consisting of exponential polynomials.
An Explanation of Mellin’s 1921 Paper
Authors:   Siberian Federal University, Lawton Wayne M.
Published: December 2023

In 1921 Mellin published a Comptes Rendu paper computing the principal solution of a polynomial using generalized hypergeometric functions of its coefficients. He used an integral transform nowadays bearing his name. Slightly over three pages, the paper is written in French in a terse style befitting the language. This article makes Mellin’s landmark result accessible to people who are not experts in hypergeometric functions and complex analysis by deriving detailed proofs that were omitted in Mellin’s paper.
THE EFFECT OF QUESTION CARD LEARNING MEDIA ON THE NUMBERED HEAD TOGETHER (NHT) COOPERATIVE LEARNING MODEL ON STUDENT LEARNING OUTCOMES IN CLASS XI MIPA MAN 1 MAKASSAR CITY (STUDY ON ACID BASE MATERIAL)
Authors: Munawwara Munawwara , Salempa Pince , Allo Eda Lolo
Published: December 2023

This is a quasi experiment research aims to determine the effect of Question Card learning media on the Numbered Head Together (NHT) type Cooperative learning model toward learning outcomes of class XI MIPA students of MAN 1 Makassar City. The research design used was a posttest-only control design. The population in the study were all students of class XI MIPA MAN 1 Makassar City which consisted of 5 classes. The research sample consisted of 2 classes, namely class XI MIPA 4 with 34 students as the experimental class and class XI MIPA 3 with 33 students as the control class. The sampling technique was carried out by simple random sampling. Data collection techniques use tests in the form of multiple choice to obtain data on learning outcomes. Learning outcomes data obtained were analyzed using descriptive and inferential statistical analysis. The results of the descriptive analysis showed that the average experimental class learning result was 77,97 which was higher than the control class learning average 69,76. The hypotesis test used is a non-parametric test, namely the Mann-Whitney test. From the data analysis results show that Zcount (2,36) > Ztable. (1,65). Based on the results of this analysis, it can be concluded that there is an influence of the question card learning media on the NHT type Cooperative learning model on the learning outcomes of students in class XI MIPA MAN 1 Makassar City on the subject matter of Acids and Bases.
Exploring the "Bigness" in Modern Architectural Design through Urban Cognition
Authors: Gao Yuanben
Published: December 2023

This paper delves into the concept of "grandness" introduced by Dutch architect Rem Koolhaas, which, in the 20th century, aligned with societal demands and propelled the development of high-rise architectural theory. However, contemporary architectural research has revealed trends of standardization and compartmentalization in large skyscrapers, which to some extent impact the diversity of urban landscapes. This paper initially discusses these constraints and explores potential future directions for "grandness," with a particular emphasis on the transformative impact of cognitive design. Large skyscrapers often lose uniqueness due to their standardization and may compromise functionality through compartmentalization. For instance, the CCTV Headquarters, while architecturally striking, generated controversy due to its lack of functional practicality. Design centered around cognition emphasizes the uniqueness and iconicity of architectural elements, compensating for the shortcomings of "grandness" by creating distinctive architectural memories. This helps large buildings become more identifiable and culturally meaningful in urban environments, integrating better into urban life. This paper aims to argue for the significance of the "grandness" concept in meeting societal needs while also highlighting some inherent limitations. Through case studies and a focus on cognitive design, a better understanding and response to these limitations can be achieved to better cater to the needs of future urban architecture.
Adaptasi Pemasaran Digital Berbasis Virtual Reality Produk UMKM Lumintu
Authors: ULUMUDDIN DIMAS IRAWAN IHYA'
Published: December 2023

Pemasaran digital muncul sebagai dampak dari meningkatnya perkembangan dan kecanggihan dunia internet dan teknologi yang menjadikan pemasaran digital ini sebagai salah satu strategi yang sangat popular dan banyak digunakan oleh hampir seluruh orang di berbagai belahan dunia untuk menarik konsumen. UMKM Lumintu memiliki kekurangan dalam pemasaran yang dilakukan yaitu masih menggunakan cara konvensional dan tidak adanya inovasi yang dilakukan. Hal ini tentu membuat kegiatan pemasaran yang dilakukan UMKM Lumintu masih kurang efektif. Salah satu inovasi yang dapat dilakukan dalam kegiatan pemasaran digital adalah melalui virtual reality. Virtual commerce adalah pengalaman tidak langsung yang dimediasi oleh komputer yang dimungkinkan oleh penggunaan realitas yang diperluas. Oleh karena itu, UMKM Lumintu membutuhkan media yang inovatif untuk mengembangkan model pemasarannya melalui teknologi virtual reality. Metode yang digunakan dalam penelitian ini adalah metode kualitatif untuk mengidentifikasi data. Dalam perancangan virtual reality akan menggunakan metode pengembangan multimedia yaitu MDLC. Hasil dari penelitian ini adalah aplikasi virtual reality yang menampilkan produk-produk dari UMKM Lumintu
TOYS AND GAMES OF PRESCHOOL CHILDREN IN UKRAINIAN REALITIES CAUSED BY WAR
Authors: Polischuk Kateryna
Published: December 2023

Military operations on territory of Ukraine changed lives of all their citizens. Ukrainian children are the most vulnerable in this situation. The article is about the changes observed in the playing activities of children  caused by war in Ukraine. The description of new methods in playing activities is the deployment of play activities in a safe, adult-defined environment (in a bomb shelter, a shelter, on a temporarily safe playground) with children who are currently nearby.The content of playing plots of preschoolers, which is caused by external circumstances, the redistribution of responsibilities in the Ukrainian family, and the emergence of multi-age play associations, is analyzed. These are such games as "war machine", "shelter", "soldiers", unfolding of game plots based on multimedia usually content not available for preschool children. A description of modern toys popular among preschoolers is given: toy weapons, military paraphernalia, new imaginative toys. Advises for parents on choosing toys and organizing play activities of preschool children are provided.Key words: modern toy, playing activity, change of game plots, children of preschool age, Ukrainian society.
FEATURES OF THE RELATIONSHIP OF CODEPENDENCE IN MIDDLE-AGED WOMEN WITH SELF-ESTEEM AND ANXIETY
Authors: Lymankina Alla
Published: December 2023

The article is devoted to the study of the relationship between middle-aged women’s codependency and self-esteem and anxiety. The essence of the definition of the phenomenon of «codependency» and different views of researchers regarding this problem are analyzed in detail. In the context of the study, it was determined that there is no single interpretation of the concept of «codependency», which indicates its multifacetedness and heterogeneity. The main features of co-dependent persons are determined. The levels of manifestation of codependency are characterized: cognitive, behavioral, emotional, activity. The main research methods are substantiated. A correlational analysis was conducted to establish the relationship between codependency and the self-esteem and anxiety scale. It was established that codependent persons have a strong correlation with the anxiety scale. It was determined that there is a strong inverse correlation between codependency and self-esteem. In this regard, it was hypothesized that this may be related to an overestimation of one’s own abilities in relation to the influence of a close dependent. On the basis of the conducted research, it is recommended to carry out psychological intervention and to point out the destructive manifestations of behavior to the co-dependent and to carry out work on their elimination.Keywords:addict, dysfunctional family, chemical dependency, autonomy, defense mechanisms.
ETIOLOGY AND LEVELS OF DIAGNOSIS OF MALIGNANT TUMORS OF THE OUTER NOSE SKIN
Authors: Yevcheva Anhelina
Published: December 2023

The paper analyzes the epidemiological indicators of the incidence of nasal skin cancer in Ukraine and Europe according to the National Cancer Registry of Ukraine in 2015 - 2018. The main etiological factors that cause the growth of nasal cancer and the role of various factors in the carcinogenesis of squamous cell carcinoma are considered. Data on methods of early diagnosis are given and the role of timely diagnosis that affects the quality of life of the patient is determined.        To prevent cancer of the external nose, the expediency of state aid in eliminating the effects of harmful environmental factors that cause the development of malignant neoplasms is discussed. The author offers suggestions for early detection and improving the diagnosis of malignant tumors of the skin of the outer nose.Keywords: malignant neoplasms, external nose, epidemiological indicators, diagnosis.
LANGUAGE STRATEGIES IN TEACHER EDUCATION: A PHILOSOPHICAL EXPLORATION OF POLICY, PEDAGOGY, AND ETHICS IN SHAPING FUTURE EDUCATORS
Authors: Gan Chzao
Published: December 2023

The philosophy of foreign language training in teacher education is a complex and multifaceted domain that intersects with a variety of educational, ethical, and sociopolitical issues. This article conducts a theoretical analysis a imedatdissecting various dimensions of language education as they pertain to the preparation of future teachers. Specifically, the paper delvesin to the role and importance of language education in teacher training, modern standards of foreign language competency, the time allocation for language training, and theethical considerations in herentin these programs. Through a critical review of the existing iterature and theoretical frame works, the article reveals the implicit and explicit philosophical underpinnings that shape current practices, evaluations, andpolicies. Among the key findings are the need for a more holistic approach to language training that extends beyond linguistic proficiency to encompass cultural competency and ethical awareness. The article concludes by highlightingth eimplications of these findings for educational policy and suggesting avenues for future research. The hopeis to contribute to a more integrated, philosophically informed understanding of language education, settingthes tage for more effective and equitable teacher preparation programs.Keywords: philosophy of education, foreign language training, teacher education, educational policy, ethical considerations.
A REFLECTIVE AND AWARE APPROACH TO THE FORMATION OF AUDITORY ATTENTION OF STUDENTS OF UNIVERSITY FACULTIES OF ARTS
Authors: Xu Li
Published: December 2023

The article breaks down the specifics of the reflexive-aware approach to the formation of auditory attention of future music teachers. This important approach allows you to reveal such facets of the personality, where its attention is directed to itself, to its consciousness, including the products of its own activity, as well as any interpretation, reinterpretation and transformation of its past experience (the content and functions of its own consciousness: personal structures (values, interests, motives), thinking, mechanisms of perception, decision-making, emotional responses, behavioral patterns, etc.). The use of a reflexive-conscious approach directs the reflective actions of the individual from self-actualization to self-realization.This provides in the process of learning the self-knowledge of the individual, the development of reflective abilities, mastering the methods of self-regulation, self-improvement, and moral self-determination, which forms the life position of a socially active individual. Reflective actions contribute to increasing the professional competence of an individual, encouraging him to acquire quality, effectiveness in pedagogical activities and mastery.Key words: reflexive-aware approach, future music teachers, auditory attention, professional competence, quality of educational activity.
Characterization of intact chitosan obtained from Bradyporus sp. (Orthoptera, Insecta) and its cytotoxicity on human cell line (HEK293)
Authors: Umran Rajaa , Mol Abbas , Mosa Amal Umran , Kaya Murat
Published: December 2023

Intact chitosan film was produced from Bradyporus sp. (Orthoptera, Insecta) and
characterized by Fourier Transform Infrared Spectroscopy (FTIR), Thermogravimetric
Analysis (TGA), X-ray diffractometer (XRD), Scanning Electron Microscopy (SEM) and
elemental analysis. MTT test was performed to determine the cytotoxic effects of chitosan.
Chitosan administered at optimal and overdose intervals was applied to HEK293 cells for 24,
48 and 72 hours. In the MTT cytotoxicity test, the IC 50 dose of chitosan was 1427 µM at 24
hours, 808.9 µM at 48 hours, and 611.6 µM at 72 hours. Considering all the conducted
analyses and cytotoxic experiments, the obtained intact novel chitosan film from the insects
could find applications for biotechnological applications.
An Online Drone Course for Construction Management Students: Curriculum, Simulation, and Certifications
Authors: Burgett Joe
Published: December 2023

It is incumbent upon higher education institutions to teach students how to use emerging technologies and best practices of advanced workflows. Unmanned aircraft systems (UAS) are rapidly expanding tools that support various industries, including construction management, civil engineering, and surveying. There are many challenges to offering a course focused on the use of an outside, hands-on tool. These challenges can be exacerbated by the online delivery method.

This paper describes the curriculum and delivery method of an online drone course taught at a large land grant institution in the southeast. The course allows students to earn their FAA Part 107 remote pilots certificate and their Airborne Public Safety Association (APSA) flight proficiency certification, and it prepares them to become a Level 1 UAS thermographer. This paper will indicate where this institution has found success and where future development is needed when offering this course online. The paper can also be a roadmap for other schools to create a similar UAS course.
An Overview of the Application of Performance Based Specifications in Concrete Construction Projects
Authors: Akhnoukh Amin
Published: December 2023

Construction projects use prescriptive codes to regulate multiple stages of concrete construction activities. Prescriptive codes are suitable for design-bid-build projects as it provides sufficient details for different project parties. Despite of its advantage, prescriptive codes represent an impediment to the potential improvement of concrete mix characteristics, including immediate mix properties, long-term performance, and concrete sustainability due to the restrictions imposed on material selection, constituent proportions and batching and mixing procedures. To improve construction projects quality and long-term performance, current federal legislatures focus on the replacement of prescriptive codes with performance-based specifications, where the concrete mix is designed and optimized to attain specific long-term performance criteria decided according to the project service conditions. This research paper presents the possible outcomes of utilizing performance-based specifications in replacement of prescriptive codes in concrete construction; and presents the changes to be adopted in project quality control procedures to ensure its successful implementation in future projects. The results of this research show that performance-based specifications are advantageous in fast-track projects, including design-build project delivery. Concrete mixes produced according to performance-specs have superior long-term performance characteristics, higher durability, and improved sustainability. Due to the increased durability, structural concrete designed and poured using performance specs need lower maintenance intervention, which reduce construction projects life cycle cost.
Analysis of Current BIM Execution Plans and Contract Documents to Support Automation of Clash Resolution
Authors: Harode Ashit , Mills Thomas , Thabet Walid
Published: December 2023

Step one of the MEP coordination process identifies the clash between MEP elements followed by step two identifying their potential resolution. Clash identification has been automated using software like Navisworks yet clash resolution remains a slow and manual process. Use of Machine Learning has been explored by researchers to automate clash resolution. These researches utilize graphical information and attributes embedded into Building Information Model (BIM) elements to develop a Machine Learning model making BIMs an integral part of the automation. The literature review shows that the successful implementation of BIMs is supported by well-executed BIM Execution Plans (BxP) and Standards. Therefore, it can be said that a successful implementation of clash resolution automation will require the support of these documents. To assess the readiness of BxP to support the automation of clash resolution, the authors in this paper reviewed three BxP and Standard guides. A comparative analysis of three industry-standard BxP and Standard guides was conducted to reveal the topic covered by them. Results from the review show that the BxPs and Standards are lacking to support the automation of clash resolution. Suggested potential changes to make these documents ready for the implementation of automation of clash resolution are discussed.
Ensuring operational performance for promoting sustainable practices in Public Private Partnership (PPP) projects in the UK
Authors: Maqbool Rashid , O'Rourke Liam , Ashfaq Saleha , Rashid Yahya
Published: December 2023

A great deal of focus has been placed by different governments on their construction industries as it is known for being a large polluter of the planet, as well as being a huge consumer of energy and emitter of carbon. The research was completed by investigating major PPP themes related to UK (namely, challenges to UK construction, operational performance of PPP projects, and drivers of PPP projects). To ensure enough participants were reached, the snowball sampling technique was used to collect data from 156 industrial professionals. Relative importance index (RII) analysis was performed to check the ranking of the factors, and to determine the significance of each factor. This analysis revealed a large significance on time and cost management issues within the challenges to UK construction section. Sustainability presented highly significant results relating to modern methods of construction like BIM as well as the use of modern schemes such as the PF2 (Private Finance 2) scheme. This was also found to be an important factor in the operational performance of PPP projects as well as resolving financial and fiscal issues within the public sector. This research can support public and private sectors to develop advanced collaborative networks to boost productivity.
Implementation of a Time Management Training Module for Freshmen Students in an Entry Level Construction Management Course
Authors: Brittle Patrick
Published: December 2023

The transition to a four-year university presents many new challenges for freshmen students transitioning from high school. Students are thrust into a situation where they are solely responsible for balancing a variety of responsibilities, ranging from completing assigned coursework, studying for exams, along with personal and social obligations. Not surprisingly, this freshmen year is the most critical timeframe in determining whether a student will persist at a four-year university. Approximately 1 in 5 freshmen will either change schools or dropout out of their university during the first year. Construction students face additional challenges given their personality tendencies. Effective time management behaviors have demonstrated improved academic performance and increased the likelihood students will persist until graduation. Unfortunately, time management practices are rarely taught at universities and students are expected to learn these behaviors on their own. This paper will demonstrate the implementation of a time management module in a first-year construction management course and assess whether this training resulted in improved academic performance for freshmen construction students.