bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of an Optimal Start Control Strategy for a Variable Refrigerant Flow (VRF) System
Authors: Lee Yusung , Kim Woohyun
Published: January 2021

In this study, an optimal control strategy for the variable refrigerant flow (VRF) system is developed using a data-driven model and on-site data to save the building energy. Three data-based models are developed to improve the on-site applicability. The presented models are used to determine the length of time required to bring each zone from its current temperature to the set point. The existing data are used to evaluate and validated the predictive performance of three data-based models. Experiments are conducted using three outdoor units and eight indoor units on site. The experimental test is performed to validate the performance of proposed optimal control by comparing between conventional and optimal control methods. Then, the ability to save energy wasted for maintaining temperature after temperature reaches the set points is evaluated through the comparison of energy usage. Given these results, 30.5% of energy is saved on average for each outdoor unit and the proposed optimal control strategy makes the zones comfortable.
Detecting Heterobasidion irregulare in Minnesota and Assessment of Indigenous Fungi on Pines
Authors: Otto Eric , Held Benjamin , Redford Samuel , Blanchette Robert A.
Published: January 2021

Heterobasidion irregulare is one of the most problematic forest pathogens in the northern hemisphere, but has only been found relatively recently in the north central United States. Discovered in Wisconsin in 1993, but probably established sometime before that, it quickly spread throughout the state. In November 2014, it was found in southeastern Minnesota. Field surveys were then conducted throughout Minnesota with the focus in the southeast near the initial discovery. To find additional infection sites, surveys were conducted with accompanying aerial imagery of red pine (Pinus resinosa Aiton) stands that were previously thinned. Samples were collected from selected sites with dead and dying trees as well as samples from stumps in recently thinned pine stands. These samples were processed first with a nested polymerase chain reaction (PCR) protocol, which was replaced by a real-time PCR assay after its development. No samples tested positive for H. irregulare using these methods and no cultures from isolations were obtained outside the original infection area. Other indigenous fungi were also identified. The majority were wood decay fungi in the Basidiomycota. A spore collection study was also conducted after field surveys. Automated rotary arm spore collectors were used and assayed with an ITS TaqMan real-time PCR assay. Collectors were placed strategically in different areas of Minnesota. A positive control was used in an infected red pine plantation in Wisconsin and this location had the highest number of spores trapped, with 63,776 over a week period. Spores of H. irregulare were detected at several sites in Minnesota, with the highest spore total observed in traps at 413 over a week period. All other locations sampled also had some spores collected except Itasca State Park located in northwestern Minnesota. The weekly deposition of spores ranged from 0 to 1.26 m−2 h−1. Low spore levels occurring in Minnesota indicate that some spores are present, but they are currently being detected in amounts that may not be sufficient for colonization to be successful.
Allometric Equations for Estimating Biomass and Carbon Stocks in Afforested Open Woodlands with Black Spruce and Jack Pine, in the Eastern Canadian Boreal Forest
Authors: Fradette Olivier , Marty Charles , Tremblay Pascal , Lord Daniel , Boucher Jean-François
Published: January 2021

Allometric equations use easily measurable biometric variables to determine the aboveground and belowground biomasses of trees. Equations produced for estimating the biomass within Canadian forests at a large scale have not yet been validated for eastern Canadian boreal open woodlands (OWs), where trees experience particular environmental conditions. In this study, we harvested 167 trees from seven boreal OWs in Quebec, Canada for biomass and allometric measurements. These data show that Canadian national equations accurately predict the whole aboveground biomass for both black spruce and jack pine trees, but underestimated branches biomass, possibly owing to a particular tree morphology in OWs relative to closed-canopy stands. We therefore developed ad hoc allometric equations based on three power models including diameter at breast height (DBH) alone or in combination with tree height (H) as allometric variables. Our results show that although the inclusion of H in the model yields better fits for most tree compartments in both species, the difference is minor and does not markedly affect biomass C stocks at the stand level. Using these newly developed equations, we found that carbon stocks in afforested OWs varied markedly among sites owing to differences in tree growth and species. Nine years after afforestation, jack pine plantations had accumulated about five times more carbon than black spruce plantations (0.14 vs. 0.80 t C·ha−1), highlighting the much larger potential of jack pine for OW afforestation projects in this environment.
Efficiency Improvement of Miniaturized Heat Exchangers
Authors: Gerken Iris , Wetzel Thomas , Brandner Jürgen J.
Published: January 2021

Micro heat exchangers have been revealed to be efficient devices for improved heat transfer due to short heat transfer distances and increased surface-to-volume ratios. Further augmentation of the heat transfer behaviour within microstructured devices can be achieved with heat transfer enhancement techniques, and more precisely for this study, with passive enhancement techniques. Pin fin geometries influence the flow path and, therefore, were chosen as the option for further improvement of the heat transfer performance. The augmentation of heat transfer with micro heat exchangers was performed with the consideration of an improved heat transfer behaviour, and with additional pressure losses due to the change of flow path (pin fin geometries). To capture the impact of the heat transfer, as well as the impact of additional pressure losses, an assessment method should be considered. The overall exergy loss method can be applied to micro heat exchangers, and serves as a simple assessment for characterization. Experimental investigations with micro heat exchanger structures were performed to evaluate the assessment method and its importance. The heat transfer enhancement was experimentally investigated with microstructured pin fin geometries to understand the impact on pressure loss behaviour with air.
Presence of Parabens and Bisphenols in Food Commonly Consumed in Spain
Authors: Gálvez-Ontiveros Yolanda , Moscoso-Ruiz Inmaculada , Rodrigo Lourdes , Aguilera Margarita , Rivas Ana , Zafra-Gómez Alberto
Published: January 2021

Given the widespread use of bisphenols and parabens in consumer products, the assessment of their intake is crucial and represents the first step towards the assessment of the potential risks that these compounds may pose to human health. In the present study, a total of 98 samples of food items commonly consumed by the Spanish population were collected from different national supermarkets and grocery stores for the determination of parabens and bisphenols. Our analysis demonstrated that 56 of the 98 food samples contained detectable levels of parabens with limits of quantification (LOQ) between 0.4 and 0.9 ng g−1. The total concentration of parabens (sum of four parabens: ∑parabens) ranged from below the LOQ to 281.7 ng g−1, with a mean value of 73.86 ng g−1. A total of 52% of the samples showed detectable concentrations of bisphenols. Bisphenol A (BPA) was the most frequently detected bisphenol in the food samples analysed, followed by bisphenol S (BPS) and bisphenol E (BPE). Bisphenol AF (BPAF), bisphenol B (BPB) and bisphenol P (BPP) were not found in any of the analysed samples. LOQ for these bisphenols were between 0.4 and 4.0 ng g−1.
Effect of Frying Conditions on Self-Heating Fried Spanish Mackerel Quality Attributes and Flavor Characteristics
Authors: Chang Lili , Lin Songyi , Zou Bowen , Zheng Xiaohan , Zhang Simin , Tang Yue
Published: January 2021

In this study, we investigated the effects of different frying conditions on the quality characteristics of fried Spanish mackerel (Scaberulous niphonius) to address the food quality degradation of self-heating fish products after frying, sterilization, and reheating. Furthermore, the effect of different moisture contents (65%, 60%, 55%, and 50%) of fried Spanish mackerel on texture, color, and microstructure after sterilization and self-heating were examined. The flavor fingerprints of different frying temperatures (140 °C, 160 °C, 180 °C, and 200 °C) coupled with the optimal moisture content were identified; furthermore, volatile organic compounds (VOCs) were studied using headspace-gas chromatography-ion mobility spectrometry (HS-GC-IMS) with principal component analysis (PCA). The results indicated that the shear force value significantly increased, while the hardness and chewiness significantly decreased simultaneously with decreasing moisture content. Samples containing 65% moisture content showed the highest L*, a*, and W values, while their b* value was the lowest, and the most clearly visible fibrous veins with tiny cracks could be observed in them. Samples fried at 160 °C and 65% moisture content exhibited the richest VOCs, with a greasy or fried aroma. Based on the PCA, there were significant differences in the sample VOCs under different frying conditions. In summary, among all treatments, frying at 160 °C with 65% moisture content resulted in the highest food quality of fish filets. The results of this study could provide a theoretical basis for improving the food quality of self-heated fish products.
Biogenic Amines’ Content in Safe and Quality Food
Authors: Martuscelli Maria , Esposito Luigi , Mastrocola Dino
Published: January 2021

Biogenic amines (BAs) are low-molecular-weight, nitrogenous compounds (mainly polar bases) coming from the decarboxylation of free amino acids or by amination or transamination of aldehydes and ketones [...]
Grape and Wine Composition in Vitis vinifera L. cv. Cannonau Explored by GC-MS and Sensory Analysis
Authors: Petretto Giacomo L. , Mercenaro Luca , Urgeghe Pietro Paolo , Fadda Costantino , Valentoni Antonio , Del Caro Alessandra
Published: January 2021

GC-FID/MS is a powerful technique used to analyze food and beverage aromas. Volatile organic compounds (VOCs) in grape berries play an important role in determining wine quality and are affected by many factors, such as climate and soil that mainly influence their relative concentrations. Wine aroma is generated by a complex mixture of compounds, and the sensory relevance of individual VOCs is far from elucidated. Herein, the VOC content (free and glycosylated) of Cannonau grape skin and juice and of Cannonau wine collected in different areas of Sardinia is explored. Wine sensory analysis was also carried out and the relationship between sensory attributes and VOCs was investigated. Although Cannonau grapes showed the same VOC fingerprint, great variability was identified between samples, although only the differences in 2-phenylethanol and benzyl alcohol concentration in the grape skins and benzyl alcohol and a terpenoid in grape juice were significantly different according to ANOVA. The correlation between VOC content and the sensory profile highlights the role played by 2-methyl-1-butanol and 2-phenylethanol in increasing wine sensory complexity.
Innovative Control of Biofilms on Stainless Steel Surfaces Using Electrolyzed Water in the Dairy Industry
Authors: Jiménez-Pichardo Rodrigo , Hernández-Martínez Iriana , Regalado-González Carlos , Santos-Cruz José , Meas-Vong Yunny , Wacher-Rodarte María del Carmen , Carrillo-Reyes Julián , Sánchez-Ortega Irais , García-Almendárez Blanca Estela
Published: January 2021

Biofilms on food-contact surfaces can lead to recurrent contamination. This work aimed to study the biofilm formation process on stainless steel plates used in the dairy industry: 304 surface finish 2B and electropolished; and the effect of a cleaning and disinfection process using alkaline (AEW) and neutral (NEW) electrolyzed water. Milk fouling during heat processing can lead to type A or B deposits, which were analyzed for composition, surface energy, thickness, and roughness, while the role of raw milk microbiota on biofilm development was investigated. Bacteria, yeasts, and lactic acid bacteria were detected using EUB-338, PF2, and Str-493 probes, respectively, whereas Lis-637 probe detected Listeria sp. The genetic complexity and diversity of biofilms varied according to biofilm maturation day, as evaluated by 16S rRNA gene sequence, denaturing gradient gel electrophoresis, and fluorescence in situ hybridization microscopy. From analysis of the experimental designs, a cleaning stage of 50 mg/L NaOH of AEW at 30 °C for 10 min, followed by disinfection using 50 mg/L total available chlorine of NEW at 20 °C for 5 min is a sustainable alternative process to prevent biofilm formation. Fluorescence microscopy was used to visualize the effectiveness of this process.
Bioactive (Poly)phenols, Volatile Compounds from Vegetables, Medicinal and Aromatic Plants
Authors: Pinto Teresa , Aires Alfredo , Cosme Fernanda , Bacelar Eunice , Morais Maria Cristina , Oliveira Ivo , Ferreira-Cardoso Jorge , Anjos Rosário , Vilela Alice , Gonçalves Berta
Published: January 2021

Polyphenols, as well as volatile compounds responsible for aromatic features, play a critical role in the quality of vegetables and medicinal, and aromatic plants (MAPs). The research conducted in recent years has shown that these plants contain biologically active compounds, mainly polyphenols, that relate to the prevention of inflammatory processes, neurodegenerative diseases, cancers, and cardiovascular disorders as well as to antimicrobial, antioxidant, and antiparasitic properties. Throughout the years, many researchers have deeply studied polyphenols and volatile compounds in medicinal and aromatic plants, particularly those associated with consumer’s choices or with their beneficial properties. In this context, the purpose of this review is to provide an overview of the presence of volatile and nonvolatile compounds in some of the most economically relevant and consumed vegetables and medicinal and aromatic plants, with an emphasis on bioactive polyphenols, polyphenols as prebiotics, and, also, the most important factors that affect the contents and profiles of the volatile and nonvolatile compounds responsible for the aromatic features of vegetables and MAPs. Additionally, the new challenges for science in terms of improving polyphenol composition and intensifying volatile compounds responsible for the positive characteristics of vegetables and medicinal and aromatic plants are reported.
A Collocation Method Based on Discrete Spline Quasi-Interpolatory Operators for the Solution of Time Fractional Differential Equations
Authors: Pellegrino Enza , Pezza Laura , Pitolli Francesca
Published: January 2021

In many applications, real phenomena are modeled by differential problems having a time fractional derivative that depends on the history of the unknown function. For the numerical solution of time fractional differential equations, we propose a new method that combines spline quasi-interpolatory operators and collocation methods. We show that the method is convergent and reproduces polynomials of suitable degree. The numerical tests demonstrate the validity and applicability of the proposed method when used to solve linear time fractional differential equations.
Whole Exome Sequencing in Coloboma/Microphthalmia: Identification of Novel and Recurrent Variants in Seven Genes
Authors: Haug Patricia , Koller Samuel , Maggi Jordi , Lang Elena , Feil Silke , Wlodarczyk Agnès , Bähr Luzy , Steindl Katharina , Rohrbach Marianne , Gerth-Kahlert Christina , Berger Wolfgang
Published: January 2021

Coloboma and microphthalmia (C/M) are related congenital eye malformations, which can cause significant visual impairment. Molecular diagnosis is challenging as the genes associated to date with C/M account for only a small percentage of cases. Overall, the genetic cause remains unknown in up to 80% of patients. High throughput DNA sequencing technologies, including whole-exome sequencing (WES), are therefore a useful and efficient tool for genetic screening and identification of new mutations and novel genes in C/M. In this study, we analyzed the DNA of 19 patients with C/M from 15 unrelated families using singleton WES and data analysis for 307 genes of interest. We identified seven novel and one recurrent potentially disease-causing variants in CRIM1, CHD7, FAT1, PTCH1, PUF60, BRPF1, and TGFB2 in 47% of our families, three of which occurred de novo. The detection rate in patients with ocular and extraocular manifestations (67%) was higher than in patients with an isolated ocular phenotype (46%). Our study highlights the significant genetic heterogeneity in C/M cohorts and emphasizes the diagnostic power of WES for the screening of patients and families with C/M.
The Association between Future Anxiety, Health Literacy and the Perception of the COVID-19 Pandemic: A Cross-Sectional Study
Authors: Duplaga Mariusz , Grysztar Marcin
Published: January 2021

Increased anxiety related to the Coronavirus Disease 2019 (COVID-19) pandemic in society and specific professional groups has been reported by many authors. Most have applied tools enabling assessing the general traits of anxiety. Tools specifically designed for an assessment of anxiety or fear related to COVID-19 have also been developed. However, no study has assessed the future anxiety in relation to the pandemic. This concept was defined by Zaleski in the end of the 20th century as the state of apprehension, fear, worry, and concern regarding unfavourable changes in the more remote personal future. The aim of this study was an analysis to establish the level and the determinants of future anxiety in Polish society related to the COVID-19 pandemic three months after the introduction of the state of epidemic. The analysis reported in the paper is based on the data obtained through a web-based survey carried out on a representative sample of 1002 Polish adults aged 18–74 years. The hierarchical linear regression model was developed for the analysis of the determinants of future anxiety from the responses to a questionnaire consisting of five items. The independent variables selected for inclusion in the model, apart from sociodemographic characteristics, encompassed health literacy (HL) and ehealth literacy (eHL), perceived health threat related to COVID-19 (PHTC19), and a COVID-19-related conspiracy belief score (CCBS) derived from three items asking about the most popular conspiracy theories. The regression model developed in the final step showed that the future anxiety scale score (FASS) was significantly associated with gender, vocational status, HL, PHTC19, and CCBS. The FASS was lower among men than women (regression coefficient (B) (standard error, SE) = −1.28 (0.39), p = 0.001), among entrepreneurs or farmers rather than among employees of the public or private sector (B(SE) = −1.55, p = 0.010), in persons with a higher HL (B(SE) = −0.43 (0.06), p < 0.001). A higher FASS was observed in respondents with higher rather than lower PHTC19 (B(SE) = 1.49 (0.17), p < 0.001) and in those with a higher CCBS (B(SE) = 0.33 (0.07), p < 0.001). The model accounted for 15.2% of the variance of the FASS. In conclusion, the COVID-19 pandemic is not only a cause of increased mental symptoms, but also of increased future anxiety. Health-related measures are significantly associated with the FASS.
Making the Invisible Companion of People with Dementia Visible in Economic Studies: What Can We Learn from Social Science?
Authors: Nguyen Kim-Huong , Comans Tracy
Published: January 2021

The dyadic perspective is important to understand the mutual influence and interdependence of both the person living with dementia and their care partner. This perspective is routinely adopted in social research programs for dementia and many dyadic interventions have been developed. However, economic evaluation and modelling to date has often failed to incorporate caregivers’ perspectives, and their respective costs and outcomes while giving care for the person with dementia. On the occasions that this has been done, caregivers were represented as “informal costs” associated with dementia. This limited perspective cannot incorporate two-way interactions of the dyad in economic evaluations of dementia programs. This paper provides an overview of the possible interactions between people living with dementia and care partners as discovered in social science literature in the past 20 years. We demonstrate the strength of the relationships and discuss strategies for incorporating the dyadic perspective in economic evaluations of dementia programs in the future.
A Qualitative Case Study on Influencing Factors of Parents’ Child Abuse of North Korean Refugees in South Korea
Authors: Ryu Wonjung , Yang Hyerin
Published: January 2021

The purpose of this study is to investigate the influencing factors of parental child abuse by North Korean refugees who are living in South Korea. In-depth interviews were conducted with five parents who escaped from North Korea. The study identified three categories of factors impacting child abuse: the weakening of family functions from past experiences before and after defection, the stress of adapting to the culture of an unfamiliar society, and low parenting self-efficacy. North Korean parents suffered from emotional and functional crises from past traumatic events and, at the same time, experienced additional acculturative stress as a “minority” after entering South Korea, even as they continued to deal with Maternal Parenting Stress. These complex factors have been shown to lead to child abuse in migrant societies. This study contemplated the context of child abuse through specific examples. The results could provide thoughtful insights into child abuse among migrants and refugee parents, and provide evidence-based intervention plans for its prevention.
Postponed Dental Visits during the COVID-19 Pandemic and their Correlates. Evidence from the Nationally Representative COVID-19 Snapshot Monitoring in Germany (COSMO)
Authors: Hajek André , De Bock Freia , Huebl Lena , Kretzler Benedikt , König Hans-Helmut
Published: January 2021

(1) Background: The COVID-19 pandemic is accompanied by various societal and economic challenges. Furthermore, it is associated with major health challenges. Oral health is a key component of health. Therefore, both curative and preventive dental visits are important during pandemics. Since there is a lack of nationally representative studies focusing on postponed dental visits and their correlates during the COVID-19 pandemic, we aimed to fill this gap in knowledge; (2) Methods: Cross-sectional data (wave 17) were collected from a nationally representative online-survey (COVID-19 Snapshot Monitoring in Germany (COSMO)) conducted in July 2020. The analytical sample consisted of 974 individuals (average age was 45.9 years (SD: 16.5, from 18 to 74 years)). The outcome measure was postponed dental visits since March 2020 (yes; no) due to the COVID-19 pandemic. Furthermore, the type of postponed dental visits was recorded (check-up/regular dental examination; pain/dental complaints; planned therapy); (3) Results: 22% of participants reported to have postponed dental visits due to the COVID-19 pandemic since March 2020, whereas 78% of individuals did not report postponed visits (“no, attended as planned”: 29.2%; “no, examining pending”: 44.9%; “no, other reasons”: 3.9%). Among individuals who reported postponed dental visits, 72% postponed a “check-up/regular dental examination”, whereas 8.4% postponed a dental visit despite “pain/dental complaints” and 19.6% postponed “planned therapy”. Furthermore, multiple logistic regressions showed that the likelihood of postponed dental visits was positively associated with being younger (aged 65 and older, OR: 0.43, 95% CI: 0.22–0.85; compared to individuals 18 to 29 years), and higher affect regarding COVID-19 (OR: 1.36, 95% CI: 1.13–1.64); (4) Conclusions: Our study showed that more than one out of five individuals postponed a dental visit—particularly check-ups and regular dental examination—due to the COVID-19 pandemic since March 2020. Several correlates of these postponed visits have been identified. This may help identify and address individuals at risk for deterioration of oral health amplified by postponed dental visits.
TMD-Unet: Triple-Unet with Multi-Scale Input Features and Dense Skip Connection for Medical Image Segmentation
Authors: Tran Song-Toan , Cheng Ching-Hwa , Nguyen Thanh-Tuan , Le Minh-Hai , Liu Don-Gey
Published: January 2021

Deep learning is one of the most effective approaches to medical image processing applications. Network models are being studied more and more for medical image segmentation challenges. The encoder–decoder structure is achieving great success, in particular the Unet architecture, which is used as a baseline architecture for the medical image segmentation networks. Traditional Unet and Unet-based networks still have a limitation that is not able to fully exploit the output features of the convolutional units in the node. In this study, we proposed a new network model named TMD-Unet, which had three main enhancements in comparison with Unet: (1) modifying the interconnection of the network node, (2) using dilated convolution instead of the standard convolution, and (3) integrating the multi-scale input features on the input side of the model and applying a dense skip connection instead of a regular skip connection. Our experiments were performed on seven datasets, including many different medical image modalities such as colonoscopy, electron microscopy (EM), dermoscopy, computed tomography (CT), and magnetic resonance imaging (MRI). The segmentation applications implemented in the paper include EM, nuclei, polyp, skin lesion, left atrium, spleen, and liver segmentation. The dice score of our proposed models achieved 96.43% for liver segmentation, 95.51% for spleen segmentation, 92.65% for polyp segmentation, 94.11% for EM segmentation, 92.49% for nuclei segmentation, 91.81% for left atrium segmentation, and 87.27% for skin lesion segmentation. The experimental results showed that the proposed model was superior to the popular models for all seven applications, which demonstrates the high generality of the proposed model.
Comparison of Secondary Metabolite Contents and Metabolic Profiles of Six Lycoris Species
Authors: Yeo Hyeon Ji , Kim Ye Jin , Nguyen Bao Van , Park Ye Eun , Park Chang Ha , Kim Haeng Hoon , Kim Jae Kwang , Park Sang Un
Published: January 2021

Quantitative HPLC analysis was performed on six different species of Lycoris herbs to investigate variation in phytochemical content, especially galantamine and phenylpropanoid-derived compounds. The contents of these compounds differed widely among the Lycoris species, with L. radiata and L. chinensis containing the lowest and highest galantamine contents, respectively. Specifically, the galantamine content of L. radiata was 62.5% higher than that of L. chinensis. Following L. radiata, L. sanguinea contained the next highest galantamine content, which was 59.1% higher than that of L. chinensis. Furthermore, a total of 12 phenylpropanoid-derived compounds were found in the different Lycoris species, where L. sanguinea, L. squamigera, and L. uydoensis had the largest accumulation of these compounds. The total phenylpropanoid content of L. sanguinea was the highest, while that of L. radiata was the lowest. Seven of the phenylpropanoid-derived compounds, rutin, quercetin, catechin, epicatechin gallate, chlorogenic acid, benzoic acid, and kaempferol, were dominant. L. sanguinea, L. uydoensis, and L. squamigera showed amounts of these seven compounds that were 5–6 times greater than those of the other species in the study. To the best of our knowledge, our results provide the most detailed phytochemical information on these species to date, which is valuable for future applications using these medicinal plants.
Relationship between Selected Trace Elements in Human Milk and Psychosocial Characteristics in Korean Early Postpartum Women
Authors: Noh Sookjin , Lee Eunjoo
Published: January 2021

This study aimed to identify the relationship between selected trace elements in human milk and depression, breastfeeding self-efficacy, sleep satisfaction, and the demographic and obstetric characteristics of lactating mothers. Forty lactating mothers recovering after birth in two postpartum care centers located in Changwon, South Korea, were studied. Calcium, sodium, iron, and selenium concentrations in human milk were analyzed using inductively coupled plasma mass spectrometry at the analysis center of Kyungnam University. Data were analyzed using descriptive statistics, the Kruskal-Wallis test, the Mann-Whiney U test, and Spearman’s correlation coefficients using an SPSS 23.0 program. There were no significant differences in concentration of selected trace elements (calcium, sodium, iron, and selenium) in human milk according to demographic and obstetric characteristics. Sodium concentration was negatively correlated with breastfeeding self-efficacy (r = −0.51, CI = −0.71 to −0.24). Selenium concentration was negatively correlated with calcium concentration (r = −0.34, CI = −0.58 to 0.38). Postpartum depression was negatively correlated with sleep satisfaction (r = −0.46, CI = −0.67 to −0.17) and with breastfeeding self-efficacy (r = −0.41, CI = −0.64 to −0.11). Breastfeeding self-efficacy was positively correlated with sleep satisfaction (r = 0.48, CI = 0.20 to 0.69). This study suggests that sodium concentration in human milk is associated with breastfeeding self-efficacy.
Demographic Assessment of Down Syndrome: A Systematic Review
Authors: Huete-García Agustín , Otaola-Barranquero Mónica
Published: January 2021

The objective of this study is to assess the evidence about the demographic transformation of the Down Syndrome population, with a specific focus on prenatal testing, and to identify sources frequently used for demographic assessment of Down Syndrome in the world. We reviewed existing studies on demographic transformations in the population with Down Syndrome, specifically birthrate indicators, under the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement. The searches were made in Medline (via EBSCO Host), Academic Search Complete (via EBSCO Host), PsycINFO (via EBSCO Host), Web of Science (Core Collection), Public Health Database (via ProQuest), and The Cochrane Library. The terms were developed through Medical Subject Headings (MESH) and American Psycological Asociation Thesaurus of Psychological Index Terms (APA). Full texts were reviewed if information was given regarding location and birthrate for a range of three years or more, and if the first and last year considered was within 1960 and 2019. We found 22 references with a period of study between 1960 and 2019 following the global spread of prenatal testing for Down Syndrome. We found a consistent association between prenatal diagnosis and birthrate, enough to explain the significant fall in the prevalence of Down Syndrome, a somewhat rising incidence of Down Syndrome related to increased maternal age and extension of fertility services in healthcare systems, a generalized use of specific congenital birth defect registries as the primary source of data, and an unclear influence of socio-cultural and territorial variables. Our findings can inform research, policy, and practice to improve the reproductive health and quality of life of the population with Down Syndrome.
Distracted Behavior of Pedestrians While Crossing Street: A Case Study in China
Authors: Hou Mingyu , Cheng Jianchuan , Xiao Feng , Wang Chenzhu
Published: January 2021

Pedestrians are the most vulnerable road users in the traffic system and thousands of pedestrians are injured or killed globally as a result of traffic crashes every year. With their popularity and enriched functions, mobile phones are playing an increasingly important role in people’s lives, and records of vehicle crashes involving pedestrians have shown the hazards caused by distraction of mobile phone use, especially in the context of crossing the street. The present study employed the theory of planned behavior (TPB) to investigate the behavior of using a mobile phone while crossing the street in China. An online questionnaire based on the TPB framework was developed to collect data, and 387 eligible samples were retained after inspection. Mobile phone use while crossing the street is prevalent in China (i.e., 53%). The results show that three standard TPB constructs (i.e., attitudes, intention and perceived behavioral control) emerged as significant predictors of the behavior of using mobile phone while crossing, and two extended constructs (i.e., situation, mobile phone involvement) also significantly predicted the behavior. In addition, for this population, intention was the strongest predictor of the behavior among these significant constructs. Moreover, the results were discussed and compared with some existing studies and safety interventions were also provided.
Patterns of Red and Processed Meat Consumption across North America: A Nationally Representative Cross-Sectional Comparison of Dietary Recalls from Canada, Mexico, and the United States
Authors: Frank Sarah M. , Jaacks Lindsay M. , Batis Carolina , Vanderlee Lana , Taillie Lindsey Smith
Published: January 2021

Close economic ties encourage production and trade of meat between Canada, Mexico, and the US. Understanding the patterns of red and processed meat consumption in North America may inform policies designed to reduce meat consumption and bolster environmental and public health efforts across the continent. We used nationally-representative cross-sectional survey data to analyze consumption of unprocessed red meat; processed meat; and total red and processed meat. Generalized linear models were used to separately estimate probability of consumption and adjusted mean intake. Prevalence of total meat consumers was higher in the US (73.6, 95% CI: 72.3–74.8%) than in Canada (65.6, 63.9–67.2%) or Mexico (62.7, 58.1–67.2%). Men were more likely to consume unprocessed red, processed, and total meat, and had larger estimated intakes. In Mexico, high wealth individuals were more likely to consume all three categories of meat. In the US and Canada, those with high education were less likely to consume total and processed meat. Estimated mean intake of unprocessed red, processed, and total meat did not differ across sociodemographic strata. Overall consumption of red and processed meat remains high in North America. Policies to reduce meat consumption are appropriate for all three countries.
Mesothelioma in Agriculture in Lombardy, Italy: An Unrecognized Risk
Authors: Mensi Carolina , Dallari Barbara , Polonioli Marco , Riboldi Luciano , Consonni Dario , Pesatori Angela Cecilia
Published: January 2021

Cohort studies showed consistently low risks for malignant mesothelioma (MM) among agricultural workers, however the investigated exposures did not include asbestos. Our aim is to describe sources of asbestos exposure of MM in agriculture. Twenty-six MM cases in agricultural or seed trades workers were identified through the MM registry of the Lombardy region, Italy in 2000–2016. Asbestos exposures were investigated through a standardized questionnaire. The most frequent exposure circumstances were recycled jute bags previously containing asbestos (11 cases) and maintenance and repair of asbestos roofs (12 subjects). Three subjects performed maintenance and repair of tractor asbestos brakes and two used asbestos filters for wine production. Our data suggest asbestos exposure opportunities in the agricultural setting, underlining the need to look for this exposure in subjects affected with mesothelioma.
Cross-Sectional Study of the Prevalence and Symptoms of Urinary Incontinence among Japanese Older Adults: Associations with Physical Activity, Health-Related Quality of Life, and Well-Being
Authors: Maeda Noriaki , Urabe Yukio , Suzuki Yuta , Hirado Daigo , Morikawa Masanori , Komiya Makoto , Mizuta Rami , Naito Koichi , Shirakawa Taizan
Published: January 2021

Urinary incontinence (UI) is a major social problem for older adults and leads to a decline in health-related quality of life (HRQoL), mental health, and physical activity. This study assessed the prevalence and symptoms of UI among older adults discharged from the hospital in Japan and investigated the association of UI symptoms with physical activity, HRQoL, and subjective well-being (SWB). By an international consultation, the Incontinence Questionnaire Short Form (ICIQ-SF) that assesses UI severity, was developed. Self-administered questionnaires were used to assess physical activity, HRQoL, SWB, and social demographic characteristics of the participants. In total, 145 participants (valid response rate, 48%; mean age, 78.6 ± 7.6 years) were included in the analysis. Multivariate logistic regression analysis was performed to identify significant factors associated with the presence of UI. Significant decreases in physical activity, HRQoL, and SWB were observed in patients with UI compared with those without UI (p < 0.05). Multivariate analysis revealed that age, number of reported conditions, and decreased SWB were associated with UI (p < 0.05). UI was associated with less physical activity and decreased mental health status in older adults (especially decreased SWB). Health-promoting measures for older adults with UI are essential for maintaining their well-being and extending healthy life expectancy.
Phytoecdysteroids Do Not Have Anabolic Effects in Skeletal Muscle in Sedentary Aging Mice
Authors: Lawrence Marcus M. , Zwetsloot Kevin A. , Arthur Susan T. , Sherman Chase A. , Huot Joshua R. , Badmaev Vladimir , Grace Mary , Lila Mary Ann , Nieman David C. , Shanely R. Andrew
Published: January 2021

Skeletal muscle mass and strength are lost with aging. Phytoecdysteroids, in particular 20-hydroxyecdysone (20E), increase protein synthesis in C2C12 skeletal muscle cells and muscle strength in young rats. The objective of this study was to determine whether an extract from Ajuga turkestanica (ATE), enriched in phytoecdysteroids, and 20E affect skeletal muscle mass and fiber size, fiber type, activation of the PI3K–Akt signaling pathway, and the mRNA levels of MAFbx, MuRF-1, and myostatin in sedentary aging mice. Aging male C57BL/6 mice (20 months old) received ATE, 20E, or vehicle (CT) once per day for 28 days or a single acute dose. Treatment did not alter body, muscle, or organ mass; fiber cross-sectional area; or fiber type in the triceps brachii or plantaris muscles. Likewise, protein synthesis signaling markers (i.e., phosphorylation of AktSer473 and p70S6kThr389) measured after either 28 days or acutely were unchanged. Neither ATE nor 20E treatment for 28 days affected the mRNA levels of MAFbx, MuRF-1, and myostatin. In conclusion, these data indicate that phytoecdysteroid treatment does not alter muscle mass or fiber type, nor does it activate protein synthesis signaling in the skeletal muscle of sedentary aging mice.
Reliability Estimation of Reinforced Slopes to Prioritize Maintenance Actions
Authors: BahooToroody Farshad , Khalaj Saeed , Leoni Leonardo , De Carlo Filippo , Di Bona Gianpaolo , Forcina Antonio
Published: January 2021

Geosynthetics are extensively utilized to improve the stability of geotechnical structures and slopes in urban areas. Among all existing geosynthetics, geotextiles are widely used to reinforce unstable slopes due to their capabilities in facilitating reinforcement and drainage. To reduce settlement and increase the bearing capacity and slope stability, the classical use of geotextiles in embankments has been suggested. However, several catastrophic events have been reported, including failures in slopes in the absence of geotextiles. Many researchers have studied the stability of geotextile-reinforced slopes (GRSs) by employing different methods (analytical models, numerical simulation, etc.). The presence of source-to-source uncertainty in the gathered data increases the complexity of evaluating the failure risk in GRSs since the uncertainty varies among them. Consequently, developing a sound methodology is necessary to alleviate the risk complexity. Our study sought to develop an advanced risk-based maintenance (RBM) methodology for prioritizing maintenance operations by addressing fluctuations that accompany event data. For this purpose, a hierarchical Bayesian approach (HBA) was applied to estimate the failure probabilities of GRSs. Using Markov chain Monte Carlo simulations of likelihood function and prior distribution, the HBA can incorporate the aforementioned uncertainties. The proposed method can be exploited by urban designers, asset managers, and policymakers to predict the mean time to failures, thus directly avoiding unnecessary maintenance and safety consequences. To demonstrate the application of the proposed methodology, the performance of nine reinforced slopes was considered. The results indicate that the average failure probability of the system in an hour is 2.8×10−5 during its lifespan, which shows that the proposed evaluation method is more realistic than the traditional methods.
“I Want to See a Drowning-Free Philippines”: A Qualitative Study of the Current Situation, Key Challenges and Future Recommendations for Drowning Prevention in the Philippines
Authors: Guevarra Jonathan P. , Franklin Richard C. , Peden Amy E.
Published: January 2021

Drowning is described as a public health challenge by the World Health Organization. This challenge faces the Philippines where drowning claims an average of 3276 lives annually (3.50/100,000 population). However, no research comprehensively documents prevention strategies implemented by government and non-government agencies at a national or local level in the Philippines. This study aimed to qualitatively explore the current situation and key challenges of preventing drowning in the Philippines through key informant interviews and make recommendations to guide prevention efforts. Interviews were conducted among government and non-government agencies involved in drowning prevention using purposive sampling. Qualitative data collected were thematically analyzed. Findings indicate government and non-government agencies implement drowning prevention programs or strategies based on the mandate of their institutions. Most commonly cited were activities related to education or information awareness, emergency and disaster preparedness, and swimming skills. It was revealed that each agency was relatively unaware of the drowning prevention programs of other agencies. A multisector approach is needed to develop coordinated and comprehensive programs and activities aimed at preventing drowning. In this way, duplication will be avoided and the minimal resources available will be used effectively to reduce the burden of drowning in the Philippines.
How Does High-Performance Work System Prompt Job Crafting through Autonomous Motivation: The Moderating Role of Initiative Climate
Authors: Li Yuan , Li Xiyuan , Liu Yujing
Published: January 2021

By invoking self-determination theory, we proposed an integrated, multilevel model to investigate the impact of a high-performance work system (HPWS) on employees’ job crafting through autonomous motivation, along with the moderation effect of initiative climate. Adopting a three-wave, time-lagged research design, we collected data from 615 employees of 54 Chinese companies. The results of multilevel path analysis revealed that (1) HPWS is positively related to employees’ job crafting; (2) HPWS has a positive impact on employees’ autonomous motivation; (3) employees’ autonomous motivation positively affects their job crafting; (4) employees’ autonomous motivation mediates the positive relationship between HPWS and employees’ job crafting; (5) initiative climate moderates the relationship between employees’ autonomous motivation and job crafting; and (6) the indirect relationship between HPWS and job crafting through autonomous motivation is also moderated by initiative climate. The findings of this study provided several implications for job crafting research and for human resource management in organizations.
Reconstruction of Multi-Temporal Satellite Imagery by Coupling Variational Segmentation and Radiometric Analysis
Authors: Case Nicola , Vitti Alfonso
Published: January 2021

Digital images, and in particular satellite images acquired by different sensors, may present defects due to many causes. Since 2013, the Landsat 7 mission has been affected by a well-known issue related to the malfunctioning of the Scan Line Corrector producing very characteristic strips of missing data in the imagery bands. Within the vast and interdisciplinary image reconstruction application field, many works have been presented in the last few decades to tackle the specific Landsat 7 gap-filling problem. This work proposes another contribution in this field presenting an original procedure based on a variational image segmentation model coupled with radiometric analysis to reconstruct damaged images acquired in a multi-temporal scenario, typical in satellite remote sensing. The key idea is to exploit some specific features of the Mumford–Shah variational model for image segmentation in order to ease the detection of homogeneous regions which will then be used to form a set of coherent data necessary for the radiometric reconstruction of damaged regions. Two reconstruction approaches are presented and applied to SLC-off Landsat 7 data. One approach is based on the well-known histogram matching transformation, the other approach is based on eigendecomposition of the bands covariance matrix and on the sampling from Gaussian distributions. The performance of the procedure is assessed by application to artificially damaged images for self-validation testing. Both of the proposed reconstruction approaches had led to remarkable results. An application to very high resolution WorldView-3 data shows how the procedure based on variational segmentation allows an effective reconstruction of images presenting a great level of geometric complexity.