bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Kesehatan dan Kualitas Daging Babi Berdasarkan Mata Rantai Peredarannya
Authors: Swacita Ida Bagus Ngurah , Suada I Ketut , Sitepu Agung Denlira , Tasia Agnes -
Published: March 2021

WHO menyatakan bahwa, sekitar 75% penyakit-penyakit baru yang menyerang manusia dalam dua dasa warsa terakhir disebabkan oleh patogen-patogen yang berasal dari hewan atau produk hewan, sehingga produk pangan asal hewan (daging) berpotensi berbahaya kepada konsumen. Oleh sebab itu aspek kesehatan dan keamanan pangan asal hewan (daging) perlu mendapat perhatian khusus.    Tujuan penelitian ini adalah menganalisis kesehatan dan kualitas daging babi dari tempat produksi sampai mata rantai peredarannya yaitu kios daging atau pasar). Penelitian ini menggunakan metode eksploratif kualitatif yaitu menganalisis kesehatan daging babi secara inspeksi, palpasi dan insisi serta kualitas daging babi diperiksa secara subjektif meliputi uji warna, aroma, konsistensi, dan tekstur, serta uji objektif meliputi uji Daya Ikat Air, Kadar Air, pH, dan awal pembusukan. Sampel penelitian diambil  dari tempat produksi (rumah pemotongan hewan Pesanggaran dan Dharmasaba) dan kios daging di Pasar Badung dan Pasar Kereneng), dengan total sampel penelitian sebanyak 100 sampel.  Data hasil penelitian dianalisis secara deskriptif kualitatif. Hasil penelitian menunjukkan bahwa daging babi dari tempat produksi sampai tempat peredarannya, kesehatannya baik (tidak ditemukan kelainan). Demikian pula, daging babi dari tempat produksi (RPH Pesanggaran maupun Dharmasaba) sampai di tempat peredarannya yaitu kios pasar Badung dan kios pasar Kereneng, kualitasnya sesuai dengan standar. Dapat disimpulkan bahwa kesehatan dan kualitas daging babi dari tempat produksi sampai mata rantai peredarannya  masih baik, sehingga dapat direkomendasi sehat, aman dan layak untuk dikonsumsi.
Perkembangan Terkini Investigasi Gen Leptin pada Ayam: Ulasan
Authors: Mahardhika I Wayan Swarautama , Daryono Budi Setiadi
Published: March 2021

Perkembangan investigasi gen pengkode leptin (LEP) pada beberapa spesies golongan aves telah dilakukan secara mendalam selama kurun waktu 20 tahun. Ekspresi gen LEP pada genom beberapa spesies aves telah teridentifikasi diantaranya Falco peregrinus dan Falco cherrug, Pseudopodoces humilis, Taeniopygia guttata, Columba livia, Haliaeetus leucocephalus, Picoides pubescens, dan Melopsittacus undulatus. Namun identifikasi genetika molekuler gen LEP pada ayam (G. gallus gallus) masih diperdebatkan. Perkembangan industri peternakan ayam lokal asli Indonesia tergolong pesat, namun masih memiliki beberapa keterbatasan salah satunya produktivitas ternak ayam lokal asli Indonesia. Pemenuhan kebutuhan pangan nasional salah satunya berasal dari sektor peternakan unggas khususnya ayam lokal asli Indonesia dengan kontribusi sebesar 23% per tahun. Peningkatan produktivitas peternakan ayam lokal asli Indonesia dapat dicapai dengan persilangan selektif. Persilangan selektif berupaya dalam meningkatkan mutu genetik ternak ayam lokal asli Indonesia dengan memberdayakan plasma nutfah ayam lokal asli Indonesia. Persilangan selektif memungkinkan dihasilkannya hibrida ayam pedaging dan petelur dengan karakteristik unggul sesuai dengan rancangan pola persilangan yang ditetapkan. Dalam proses persilangan selektif dibutuhkan penerapan genetika Mendelian dan molekuler sebagai panduan dan evaluasi arah seleksi guna meningkatkan efektivitas persilangan. Beberapa gen yang berpengaruh signifikan terhadap produktivitas ayam telah berhasil diidentifikasi, namun beberapa kandidat gen penting lainnya seperti gen LEP masih membutuhkan riset yang mendalam. Ulasan ini mengintegrasikan riset gen LEP pada ayam dari awal penemuan hingga terobosan terkini.
Increased Tax Avoidance By Leverage Through Corporate Social Responsibility Disclosure
Authors: Pattiasina Victor , Rina Sejati Fajar , Yamin Noch Muhamad , Aldrin Akbar Muhamad , Prasetyaningrum Septyana , Nugrohowati Nur Fitriani , Yohanes Tamaela Eduard , Said Perintah Stia
Published: March 2021

This study aims at examining and analysing the effect of leverage on tax avoidance. The moderating variable is disclosing corporate social responsibility. The population in the current study is manufacturing companies in the consumer goods industry sector. The companies were listed on the Indonesia Stock Exchange (ISE) from 2013 to 2017. To examine the hypotheses, Moderation Regression Analysis (MRA) was applied. The results prove that leverage has a positive and significant effect on tax avoidance. Moreover, the corporate social responsibility disclosure is proven to strengthen the effect of leverage on tax avoidance.

Keywords: Leverage; Tax Avoidance; Corporate Social Responsibility.
Teks Satua Galuh Payuk Analisis Sosiologi Sastra
Authors: Yanthi Ni Putu Dian Kartika , Rai Putra Ida Bagus , Sutama Putu
Published: March 2021

This research discusses about Bali’s literature work purwa or traditional which shaped in satua with title “Satua Galuh Payuk text: Analysis of Sociology Literature”. The research purpose is to knowing the shaped structure and narrative structure also the social aspects which included in the satua itself. This research is using the theoretical structure and sociology approaching. Those theories used by combining some opinions from the literature experts. The method of this research on providing the data was through observation and heeding, on data analysis the researcher was used qualitative method. The method on providing the result of data analysis the researcher was used the informal method. For supporting all of the methods that have been used the researcher used some techniques which are: recording, transliteration translating, analytic descriptive, and deductive inductive. The results of this research is the shape structure and the narrative structure from “Satua Galuh Payuk Text”. The shape structure includes the language styles and diction and the narrative structure includes: incident, plots, background, figure and characterization, theme and mandate. Besides, this research was also analyzed the social aspects which become objects from the research which are naming, love aspect, civilization aspect, leadership aspect, religion aspect which consist of philosophical aspect, moral aspect and ceremony aspect.
Tindak Tutur Asertif dalam Drama 5 Ji Kara 9 Ji Made Karya Shin Hirano
Authors: Chandrayani Ni Made Ary Puspita , Andry Anita Dewi Ni Made
Published: March 2021

This study entitled Tindak tutur asertif dalam drama 5 ji kara 9 ji made karya Shin Hirano. In addition, this study is to find out the perlocutionary effect that was inflicted by the speaker towards the interlocutors through the assertive illocutionary act. Furthermore, this study applied a theory concerning speech act proposed by Searle (1985).  In terms of analyzing data, the method and technique of identity method (metode padan) with a pragmatic approach was applied in this jurnal. The result, that there were 19 data which were assertive utterances. The data in the form consists of 4 assertive speech data that serves to suggest, 4 assertive speech data with complaining function, 5 assertive speech data with notification function, 3 data with proud function, and 3 data with reporting function. The form of the perlocutionary effect found in interpersonal conversations is convincing, persuading, inciting, apologizing, expressing thanks, making anger, rejecting requests, mocking, and distrust.
A importância da relação médico-paciente para o tratamento oncológico: uma revisão bibliográfica
Authors: Portela Elissa de Carvalho , Caldas Igor Azevedo , Ribeiro Isabella Araújo , Pinheiro Sávio Régis Mesquita , Silva Vinícius Diego Mendes , Beltrão Renata Paula Lima , Da Silva Augusto Cesar Beltrão
Published: March 2021

Objetivo: O objetivo desta revisão é verificar de que maneira a relação médico-paciente pode interferir positivamente no processo de tratamento de pacientes com câncer. Revisão bibliográfica: O câncer se tornou uma das patologias mais temíveis na sociedade atual. As singularidades que exige o seu tratamento consideram a forte necessidade de uma abordagem biopsicossocial do problema e de um cuidado humanizado em direção a pacientes e familiares, uma vez que ocasiona desordens psicológicas e emocionais que afetam, inclusive, a vivência de qualidade de vida dos acometidos pela doença. A patologia do câncer, propriamente dita, resulta em dor e desconforto, assim como seu tratamento químico, que amplia a fragilidade dos pacientes. Além disso, a rotina de tratamento torna-se exaustiva, à medida que implica a necessidade de um retorno frequente ao ambiente hospitalar e na exposição a medicamentos que provocam a lassidão do paciente. Considerações finais: A relação médico-paciente se faz enquanto aspecto crucial para o tratamento de pacientes oncológicos, tendo em vista que permite aos acometidos melhores formas de lidar com a doença e com a vida em sociedade para além do hospital, promovendo o bem-estar desses indivíduos.
Prevalência de tricomoníase e coinfecções em mulheres atendidas em dois centros de saúde em um município do Pará
Authors: De Sousa Maiza Silva , Pantoja Paulo Victor Gomes , Gomes Elisângela Silva , Oliveira Amanda Louise Rodrigues , Vasconcelos Ana Oneide Brito , Silva José Henrique Santos , Almeida Maria das Graças Carvalho
Published: March 2021

Objetivo: Determinar a prevalência de tricomoníase e coinfecções associadas em mulheres atendidas em dois centros de saúde localizados em um município do estado do Pará e correlacionar essas informações com variáveis sociodemográficas. Métodos: Trata-se de estudo retrospectivo, observacional, com abordagem quantitativa, realizado em duas unidades de saúde no estado do Pará, entre março e dezembro de 2019. A amostra foi constituída de 520 prontuários de mulheres atendidas entre janeiro de 2012 a dezembro de 2017, com idades entre 18 e 55 anos, apresentando diagnóstico para tricomoníase e/ou outras infecções. Resultados: A prevalência de T. vaginalis registrada para as duas unidades foi de 0,96%. Quando associada a variáveis sociodemográficas, todas residiam no estado do Pará e se autodeclararam pardas; 0,58% eram do lar, com idades entre 28-32 anos, casadas e negavam o uso de anticoncepcional; apenas 0,38% possuíam ensino médio completo. A prevalência de coinfecções envolvendo T. vaginalis foi de 1,02%. Conclusão: Identificou-se baixa prevalência de tricomoníase no município, mas foram identificadas outras IST’s de elevada importância epidemiológica. Além disso, a pesquisa traz uma inquietação sobre o tema e importante contribuição científica por ser a primeira investigação da doença no estado do Pará e a segunda da região Norte do país.
Differential Impact of COVID-19 on Urban Versus Rural Dermatologic Practice Logistics and Recovery: A Cross-Sectional Investigation of the First Wave
Authors: Marson Justin , Litchman Graham , Rigel Darrell
Published: March 2021

Background: COVID-19 materially delayed patient visits and potential skin cancer biopsies/diagnoses among US dermatology practices. However, given a likely heterogenous impact across the US, this study sought to determine COVID-19’s effect on urban versus rural dermatology practices.
Methods: Data were analyzed from the first 1000 responses to 3 pre-validated surveys of 9891 practicing US dermatologists comparing outpatient volumes and scheduling issues for the week of February 17th to the week of March 16th (Survey 1), April 13th (Survey 2) and May 18th, 2020 (Survey 3). First 3 US zip-code digits were compared to US Census Bureau data to determine “Urban/Rural” status. Representativeness with AAD membership was confirmed. Statistical significance was calculated using chi-square with Marascuilo procedure and two-tailed independent t-test/ANOVA with post-hoc Tukey-Kramer testing.
Results: In April 2020 urban practices reported more closed practices (21.4% vs 5.8%, p<0.0001) and predicted significantly larger patient volume decreases (-45.2%  vs -31.4%, p<0.0001) and practice closures (11.9% vs. 2.5% p<0.0001) in the following 2 weeks. In May 2020, urban areas saw significantly fewer patients/week (90.9 vs 142.4 p<0.0001), larger decrease in patient volume relative to May 2019 (-49.4% vs -35.1%, p<0.0001), and conducted more telemedicine visits (27.0% vs 15.1%, p<0.0001). Significantly more rural practices reported already being at baseline volume (Mean Difference 6.2%, 95% CI 2.7%-9.8%) while urban practices predicted return to baseline volume by August (5.7, 95% CI 2.1%-9.3%) or were unsure (5.6, 95% CI 1.6%-9.7%).
Conclusion: The initial COVID-19 pandemic differentially affected urban dermatology practices. The effects of the pandemic were mitigated in part by increased use telemedicine. Future studies may further elucidate COVID-19’s effect on clinical practice and highlight areas for improvement in practice logistics and patient care.
Use of Absorbable Cutaneous Sutures Amid the COVID-19 Pandemic
Authors: Hoyer Paige , Croley Julie , Wagner, Jr. Richard F.
Published: March 2021

The use of absorbable epicuticular sutures is highlighted as a measure to decrease the number of patient visits, eliminating the risk of additional exposures for patients and medical staff during the COVID-19 pandemic.  We present a case where the use of absorbable epicuticular sutures was preferred over non-absorbable sutures. Studies have shown no significant difference in cosmetic outcomes between non-absorbing suture and absorbable suture. Many patients express anxiety over the thought of suture removal, and often ask if the sutures will “dissolve on their own” during the surgery. Use of absorbable top sutures is one way surgeons can help allay this fear, and studies have shown similar patient satisfaction between absorbable and non-absorbable sutures. Additional stress may be prominent during the current pandemic. Dermatologic surgeons should strongly consider the use of absorbable cutaneous sutures during this pandemic, as this likely improves patient and staff safety, and studies have shown similar cosmetic outcomes and patient satisfaction.
Quantum guessing via Deutsch-Jozsa
Authors: Nathanson Michael
Published: March 2021

We examine the "Guessing Secrets" problem arising in internet routing, in which the goal is to discover the identity of two objects from a known finite set $\Omega$ by asking yes/no questions. The best known classical algorithm requires $O(\log N)$ questions and $O(\log^2 N)$ steps to process the answers, where $N = \vert \Omega \vert$. We apply the Deutsch-Jozsa algorithm and show that the number of necessary calls to the oracle is independent of the size of the domain and that the output from each run of the algorithm has immediate meaning. In doing so, we extend the types of questions that the quantum algorithms can be used to solve.
Link between Diabetes and corona virus disease – A review study
Authors: Aishwarya Jaodand
Published: March 2021

Diabetes is one of the main comorbidities related to the seriousness of every one in three known human pathogenic corona virus contaminations, including extreme intense respiratory disorder. Diabetic cases have expanded dangers in serious complexities involving Respiratory Distress Syndrome and MODS disappointment. Contingent upon worldwide district, twenty–half of cases in the Corona virus infection pandemic were diabetics. Given the significance of a connection linked corona virus disease and diabetes; we have shaped a global board of specialists amongst the branch of diabetes and endocrinology to give certain direction & functional suggestions in administration of diabetes during corona virus infection. We mean to quickly give understanding in likely robotic connections between the Corona virus illness & diabetes, current down to earth the board proposals, and expound on the various requirements of a few patient gatherings. Scant information exist with respect to glucose digestion and improvement of intense difficulties of diabetes example ketoacidosis in patients with COVID-19. Contamination of corona virus in those with diabetes potentially triggers higher pressure conditions, with more prominent arrival of hyperglycemic hormones, e.g., glucocorticoids and catecholamines, prompting expanded blood glucose levels and irregular glucose inconstancy. Then again, a review concentrate from Wuhan revealed that around 10% of the patients with type 2 diabetes mellitus and Corona virus illness endured in any event one scene of hypoglycemia less than 3.9 mmol/L. Hyperglycemia appeared to assemble favorable to fiery monocytes and increment platelet reactivity, adding to a higher cardiovascular mortality in patients with diabetes.
The Emergence of Long Haul - continuing typical Covid-19 symptoms long after infection
Authors: Sneha Patil  , Rajanikanth K
Published: March 2021

Since December 2019 COVID-19 pandemic have affected the whole world and due to this, there is a rapid increase in demand of health care system of global communities. Coronavirus, so called COVID-19, is causing a flu-like common cold and many people come back to normal healthy life without any side effects. While in other case, people who have survived mild covid-19 infections are facing health issues while carrying the symptoms such as headaches, chest pain, muscle pain, neurocognitive problems, metabolic disruption that are lasting for more than weeks or months which makes people’s recovery prolonged due to weak antibody response. It is not well-defined yet but is still in the infancy stage of research and the term "Long-haulers" is used to differentiate individuals with the symptoms which may develop or persist after the initial infection with pathogenesis and an indefinite duration as it manifests itself in different variant which makes it difficult for a single treatment approach. Side effects are as notably heterogeneous as found in acute COVID-19 and might be steady, change, or show up and be supplanted by symptoms identifying with different frequency. "Long hauler," is a person who tested negative experiences the same set of symptoms long after recovery from covid-19. Numerous people with long-COVID will be overseen in essential consideration, others will require more attention from recovery medication specialists.
Note on composition of entire functions and bounded $L$-index in direction
Authors: Bandura A. I. , Skaskiv O. B. , Salo T. M.
Published: March 2021

We study the following question: ``Let $f\colon \mathbb{C}\to \mathbb{C}$ be an entire function of bounded $l$-index, $\Phi\colon \mathbb{C}^n\to \mathbb{C}$ an be entire function, $n\geq2,$ $l\colon \mathbb{C}\to \mathbb{R}_+$ be a continuous function. What is a positive continuous function $L\colon \mathbb{C}^n\to \mathbb{R}_+$ and a direction $\mathbf{b}\in\mathbb{C}^n\setminus\{\mathbf{0}\}$ such that the composite function $f(\Phi(z))$ has bounded $L$-index in the direction~$\mathbf{b}$?'' In the present paper, early known result on boundedness of $L$-index in direction for the composition of entire functions $f(\Phi(z))$ is modified. We replace a condition that a directional derivative of the inner function $\Phi$ in a direction $\mathbf{b}$ does not equal zero. The condition is replaced by a construction of greater function $L(z)$ for which $f(\Phi(z))$ has bounded $L$-index in a direction. We relax the condition $|\partial_{\mathbf{b}}^k\Phi(z)|\le K|\partial_{\mathbf{b}}\Phi(z)|^k$ for all $z\in\mathbb{C}^n$,where $K\geq 1$ is a constant and ${\partial_{\mathbf{b}} F(z)}:=\sum\limits_{j=1}^{n}\!\frac{\partial F(z)}{\partial z_{j}}{b_{j}}, $ $\partial_{\mathbf{b}}^k F(z):=\partial_{\mathbf{b}}\big(\partial_{\mathbf{b}}^{k-1} F(z)\big).$ It is replaced by the condition $|\partial_{\mathbf{b}}^k\Phi(z)|\le K(l(\Phi(z)))^{1/(N(f,l)+1)}|\partial_{\mathbf{b}}\Phi(z)|^k,$ where $N(f,l)$ is the $l$-index of the function $f.$The described result is an improvement of previous one.
Averaging method for impulsive differential inclusions with fuzzy right-hand side
Authors: Skripnik N. V.
Published: March 2021

In this paper the substantiation of the partial scheme of the averaging method for impulsive differential inclusions with fuzzy right-hand side in terms of R - solutions on the finite interval is considered.Consider the impulsive differential inclusion with the fuzzy right-hand side $$\dot x \in \varepsilon F(t,x) ,\ t \not= t_i,\ x(0)\in X_0,\quad\Delta x \mid _{t=t_i} \in \varepsilon I_i (x),\qquad\qquad\qquad\qquad\qquad\qquad\qquad (1)$$ where $t\in \mathbb{R}_+ $ is time, $x \in \mathbb{R}^n $ is a phase variable, $\varepsilon > 0 $ is a small parameter,$ F \colon \mathbb{R}_+ \times \mathbb{R}^n \to \mathbb{E}^n,$ $I_i \colon \mathbb{R}^n \to \mathbb{E}^n $ are fuzzy mappings, moments $t_i$ are enumerated in the increasing order.Associate with inclusion (1) the following partial averaged differential inclusion $$\dot\xi \in \varepsilon \widetilde F (t, \xi ),\ t \not= s_j ,\ \xi (0) \in X_0,\quad \Delta \xi \vert _{t=s_j} \in \varepsilon K_j (\xi ),\qquad\qquad\qquad\qquad\qquad\qquad\quad (2),$$ where the fuzzy mappings $ \widetilde F \colon \mathbb{R}_+ \times \mathbb{R}^n \to \mathbb{E}^n ; \quad K_j \colon \mathbb{R} \to \mathbb{E}^n $ satisfy the condition $$\lim _{T \to \infty } \frac 1T D \Big( \int\limits_t^{t+T} F(t,x) dt + \sum_{t \leq t_i < t+T} I_i (x),\int\limits_t^{t+T} \widetilde F(t,x)dt +\sum_{t \leq s_j < t+T} K_j (x) \Big) = 0,\quad\quad (3)$$ moments $s_j$ are enumerated in the increasing order. In the paper is proved the following main theorem:{\sl Let in the domain $ Q = \lbrace t \geq 0 , x \in G\subset \mathbb{R}^n \rbrace $ the following conditions fulfill:$1)$ fuzzy mappings $ F (t,x), \widetilde F(t,x), I_i(x),K_j(x) $are continuous, uniformly bounded with constant $M$, concave in $x,$ satisfy Lipschitz condition in $x$ with constant $ \lambda ;$$2)$ uniformly with respect to $t, x$ limit (3) exists and $\frac 1T i(t,t+T) \leq d < \infty ,\ \frac 1T j(t,t+T) \leq d < \infty,$where $i(t,t+T)$ and $j(t,t+T)$ are the quantities of impulse moments $t_i$ and $s_j$ on the interval$ [ t, t+T ] $;$3)$ {\rm R}-solutions of inclusion (2) for all $ X_0 \subset G^{\prime} \subset G $for $ t \in [0,L^{\ast} \varepsilon ^{-1} ] $ belong to the domain $G$ with a $ \rho $- neighborhood.Then for any $\eta > 0 $ and $L \in (0,L^{\ast}]$ there exists $\varepsilon _0 (\eta,L) \in (0,\sigma ] $ such that for all $\varepsilon \in (0, \varepsilon _0 ]$ and $t \in [0,L \varepsilon ^{-1}] $ the inequality holds:$D(R(t, \varepsilon ), \widetilde R (t, \varepsilon)) < \eta,$ where $R(t, \varepsilon), \widetilde R(t, \varepsilon ) $ are the {\rm R-} solutions of inclusions (1) and (2), $R(0, \varepsilon ) = \widetilde R (0, \varepsilon).$
THE SUBJECT OF OF “VOGUE” AND “HARPER’S BAZAAR” MAGAZINES
Authors: Mykhayliv Natalya
Published: March 2021

In the article according to the theory of the subject, patterns of the existence and genesis of the subject of “Vogue” and “Harper’s Bazaar” (USA) magazines was analysed, perspective of the emergence of new subjects was established, classification of the current subjects into universal and synthetic was suggested and some regularities of authorial creation of new subjects was examined. The main objective of the study is to identify patterns of existence of actual and formation of new topics in the Means of Mass Communication on the example of “Vogue” and “Harper’s Bazaar” magazines. In studying of the empiric basis of the research the method of observation is applied; in finding common themes for both publications – a comparative method was used. The method of analysis was used in the decomposition of topics into separate topics; in isolation from the features of the topic, uncharacteristic of a journalistic work – abstraction was applied. The elucidation that the subject appears as a formal verbal expression of a set of homogeneous topics was done by applying the method of formalization. The main results of the research are: obtaining the new classification of topics of “Vogue” and “Harper’s Bazaar” magazines; identification of a significant manifestation of universal themes on the pages of publications; establishment of the basic subjective (deontological) bases of formation of new subjects. A theoretical level of their knowledge will enrich science, equip practice, promote individual and world harmony.
Ritual Mistis di Dunia Politik: Studi pada Ritual Ngalab Berkah di Gunung Kemukus
Authors: ZULKARNAEN AHMAD
Published: March 2021

Hasil penelitian Menyebutkan bahwa Masyarakat di zaman modern ini masih tetap memegang budaya ritual mistis, kepemimpinan kharismatik menyebabkan ritual mistis tetap laris di kalangan kontestan politik, Hasil dari ritual mistis yang berupa Ngalab Berkah di Gunung Kemukus, menjadikan pelaku ritual mendapatkan harmonisasi antara makrokosmos dan mikrokosmos, kharisma sebagai pemimpin, mendapat pulung (kebegjan), serta mendapatkan hikmat dan belas kasihan dari Pangeran Samudra. Ritual mistis yang dijalankan oleh para peziarah terbukti sebagai jalan yang cukup ampuh untuk ditempuh para kontestan politik dalam memenangkan kontestasinya di dunia politik.
LIMD2 is differentially expressed in lymph node metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: March 2021

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). Between the breast and the brain reside the secondary lymphoid organ, the lymph nodes. We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with metastasis to the lymph nodes in humans with metastatic breast cancer. We found that LIM domain containing 2, LIMD2, was among the genes whose expression was most different in the lymph node metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. LIMD2 mRNA was present at increased quantities in lymph node metastases as compared to primary tumors of the breast. Importantly, expression of LIMD2 in primary tumors of the breast was correlated with patient post-progression survival, in lymph node positive patients but not in lymph node negative patients. Modulation of LIMD2 expression may be relevant to the biology by which tumor cells metastasize from the breast to the lymph nodes and the brain in humans with metastatic breast cancer.
Dominance hypothesis is far from sufficient to explain heterosis
Authors: Pei Donghong
Published: March 2021

Although heterosis has contributed to reducing hunger and malnutrition over the past 100 years, itsgenetic basis remains a matter of conjecture. The dominance hypothesis has mostly held sway, andimplies that, if the vast majority of deleterious recessives could be purged, the advantage of thehybrids over the inbreds should become negligible. Therefore, it is important to compare heterosiswith contribution from dominance to assess the magnitude of contribution. However, because of thecomplexities of multigene quantitative traits, the assessment remains impossible in practice. Here,focusing on diploid plants, with the consideration that dominance alone contributes to heterosis, wedevelop the expression for calculating the ratio of heterosis to midparent value, and determine themaximum ratio. We demonstrate that the maximum ratio is practically unachievable, and is muchlower than the ratios of heterosis to midparent yield exhibited by most of the elite maize hybrids andtheir parents in the well-designed experiment. Therefore, we conclude that the dominancehypothesis is far from sufficient to explain heterosis. Our results raise the possibility that theadvantage of elite hybrids over concurrently developed elite inbred lines can always be maintained by breeding efforts. Our work provides new insights into the role of dominance in heterosis, and isanticipated to pave the way for expanding our understanding of heterosis.
Relating phrase production and comprehension: animacy interactions with individual variability suggest similar lexically-driven conflict resolution processes
Authors: Wu Shi Hui , Henderson Lisa , Gennari Silvia
Published: March 2021

What cognitive processes might underpin sentence production and comprehension? Although access to vocabulary is likely shared across these tasks, the nature of potentially common mechanisms remains elusive, with current proposals arguing for common prediction processes or domain-general conflict resolution mechanisms. Here we explore this issue and specifically asks whether phrase production and comprehension may each recruit similar conflict-resolution mechanisms that are not solely explained by shared linguistic knowledge.
In vitro anti-inflammatory and anti-proliferative potential of roots extract of Euphorbia hirta Linn
Authors:   PhD Scholar, K.R. Mangalam University, School of Medical and Allied Sciences, Deptt. of Pharmacy, Sohna Road, Gurgaon – 122103, Haryana, India, Rashmi  , Gupta Pankaj ,   Assistant Professor, K.R. Mangalam University, School of Medical and Allied Sciences, Deptt. of Pharmacy, Sohna Road, Gurgaon – 122103, Haryana, India
Published: March 2021

Aim: The main aim of this current study was to characterize the anti-inflammatory and anti-proliferative activities of alcoholic extract of the roots of euphorbia hirta. Genus Euphorbia contains many therapeutic plants which are widely studied. This study is designed to explore the effects of alcoholic roots extract of euphorbia hirta, on selected cell lines of Human Breast cancer (MCF - 7). Methods: The Human Breast Cancer cell lines i.e. MCF – 7 cell lines were treated with alcoholic roots extract of euphorbia hirta at different concentrations. Anti-proliferative effect of the alcoholic extract was evaluated by assessing the cell viability. MTT assay was used to determine the cell viability at the wavelength of 570 nm. Antiinflammatory potential of extract was evaluated by calculating the percentage inhibition of protein denaturation. Results: The results showed the significant anti-inflammatory potential as it effectively inhibits the protein denaturation. The alcoholic roots extract of euphorbia hirta also showed moderate cytotoxic effect against MCF - 7 cell-lines (P ≤0.05). Conclusions: The results showed that this extract had significant anti-inflammatory potential and moderate anti-proliferative effect, as extract was able to inhibit the proliferation of tumor cells. Hence, it seems to be a virtuous contender to protect against growth of tumor cells.
Second Wave of COVID-19 Pandemic in Malaysia and the Impact on Nuclear Cardiology Services: An Institutional Experience
Authors: Zanial Ahmad Zaid , Aminudin Syifaa , Mohamad Najib FatinHayani , Hassan Siti Zarina Amir
Published: March 2021

Introduction: Nuclear cardiology applying radioactive tracer and hybrid imaging techniques are able to provide information needed to detect and evaluate ischaemic heart diseases. In our centre, nuclear cardiology services involving stress and rest myocardial perfusion scans and viability studies contribute about 40% of overall scan workload. The second wave of COVID- 19 pandemic in Malaysia announced by the end of February 2020 has affected nuclear cardiology services.Objectives: Our aims were to determine the impact of COVID-19 pandemic second wave on the nuclear cardiology imaging studies performed as well as to ascertain crucial institutional experience especially unavoidable problem and adjustment during the period.Methods: A review of Technetium-99m tetrofosmin radiopharmaceutical dispensing data and scan records for 1st February to 31st August 2019 and 2020 was conducted at Nuclear Medicine Department, Hospital Kuala Lumpur. Figures were compiled and statistical analysis done. Survey and focus discussion conducted involving nuclear medicine physicians, pharmacists and physic officers to identify the main difficulty faced and most important Job-adapting measure taken.Results: A total of 1109 cardiac radiopharmaceutical doses dispensed during the studied period but were less when compared to 1342 doses dispensed last year. Significant reduction was noted in April and May 2020 with only 69 and 67 cases respectively in comparison with monthly average of 192 cases in 2019. Although some scan appointments were postponed to avoid the usual waiting area congestions, the main difficulty faced was Technetium-99m generator supply disruption with limited production in Europe and international transportation restriction. Implementing infection control standard operating procedure (SOP) instructions as part of routine work practice with emphasis of time, distance and shielding concept was the most important Job-adapting measure.Conclusion: Nuclear cardiology services were affected by the second wave of COVID-19 pandemic locally. Main problem ascertained was disruption of radioactive supply. Most important adjustment was infection control SOP implementation.International Journal of Human and Health Sciences Supplementary Issue: 2021 Page: S25
LABORATORY CONTROL OF ANTICOAGULANT PROPHYLAXIS IN PREGNANT WOMEN WITH CARDIOVASCULAR DISEASES
Authors: V. Medved  , T. Savka
Published: March 2021

This article examines the effect of anticoagulant prophylaxis on pregnancy, childbirth and the postpartum period in women with heart disease. Тhe main mechanisms of formation of side effects from anticoagulant prophylaxis in pregnant women with diseases of the cardiovascular system were studied by means of laboratory research methods,. Have been studied the effects and interaction of different types of anticoagulant prophylaxis and aspirin prophylaxis on primary hemostasis. An algorithm for diagnosing the negative effect of anticoagulants on platelets has been developed. The study examines the possibility of drug correction of the development of side effects from anticoagulant thromboprophylaxis for women with diseases of the cardiovascular system.
Single Dose of Methotrexate Therapy Followed By Suction Curettage for Management of Cesarean Scar Pregnancy
Authors: Saleh Hend
Published: March 2021

Objective Implantation of the pregnancy in a cesarean scar is a rare condition named ; Cesarean scar pregnancy (CSP). Maternal complications can be prevented with the early diagnosis and an appropriate management .It is a Prospective clinical study to evaluate the efficacy and success rate of single dose use of methotrexate (MTX) followed by dilation and suction (D&S) regimen in management of women with cesarean scar pregnancy (CSP) . Methods 50mg of MTX in the form of a single dose Intramuscular injection then cervical dilatation and suction aspiration with a Karman cannula(D&S) under guidance of ultrasound after 48 preeceeded by vaginal misoprostol 2 tablet (200 mg) 4 hours ago. Results The mean gestational age at diagnosis was (8.5±1.6 ) and The mean level of serum b-human chorionic gonadotropin was (7424±2.560 ) and The mean gestational age of pregnancy was (8.5±1.6 ) .88.7% is the successive rate without complication need intervention, 2 (5.7%) patients needed intrauterine Foley's catheter for 24 hours as a mechanical hemostasis . 2 (5.7 %) had laparotomy with wedge resection of the gestational sac lesion and successful repair of the uterine defect and one (2.8 %)underwent subtotal hysterectomy. Conclusion: Systemic single dose MTX injection followed by D&S is an effective and harmless management for CSP. Nevertheless more studies are required to prove the efficiency, safety, and reproductive outcome of variant modalities in treatment of CSP.
Stress in Pregnancy: It's Implications in Mother and Child
Authors: Srivastava Pankaj
Published: March 2021

Stress commonly associated with today’s daily life has quite varied effect on pregnant females. Stress also affects general well-being of an individual but in pregnancy it is affecting two lives: the womb bearer and the one residing inside it. There is a steady rise in complications due to stress in pregnancies leading to increased rate of abortions, pre-term deliveries, PIH, GDM and IUGR in fetus. It also influences the neural development of the fetus causing adverse effects in later life.
Effectiveness of Structured Teaching Programme on Knowledge of Preparation and Management of Labour among Primigravida Women in Selected Hospital, Salem
Authors: Santhi Santhi
Published: March 2021

Pregnancy is a special event in women’s life, as it is unique for the mother child binominal. Maternal and neonatal morbidity and mortality remain unacceptably high, despite a focus on improving the health of pregnant women and newborns through Millennium Development Goals 4 and 5. The main aim of this study is to identify the level of knowledge on preparation and management of labour among primigravida women in the age group of 20-35 years. A pre experimental one group pre test and post test design was selected and purposive sampling technique was adapted to recruit the sample. The sample size was 30. Tools like demographic variables, structured interview schedule and structured teaching programme on preparation and management of labour were used. At the first day, pre test was conducted and structured teaching on preparation and management of labour was administered for group of antenatal women. After one week post test was conducted by same tool. Data analysis was done by using both descriptive and inferential statistics. Majority (50%) of the women were in the age group of 21-25 years. The overall mean score in pre test was 12.16±4.4 and the mean percentage was 40.53. In post test the overall mean score was 22.76±7.26 and the mean percentage was 75.87. The calculated ‘t’ value is 10.18 at 0.05 level of significance. It depicts that structured teaching on preparation and management of labour was highly effective. There was no significant association between the demographic variables of primigravida women and the pre and post test knowledge scores.
A Beacon for Gynaecological Cancers Patients: pH-Sensitive Nano medicine
Authors: Prasad Pramod
Published: March 2021

Emergence of various Nano scale drug carrier platforms as Drug Delivery Systems (DDS) has revolutionized the field of medicine. Nonetheless, the side-effects due to non-specific distribution of anticancer therapeutics in normal, healthy tissues remain to be a prime pitfall in curing cancers. Therefore, to achieve a better therapeutic efficacy, the use of a target-specific delivery, combined with a stimuli-responsive Nano carrier system, particularly pH-sensitive Nano systems offer an attractive strategy. Targeted drug delivery through pH-sensitive Nano systems offer the potential to enhance the therapeutic index of anticancer agents, either by increasing the drug concentration in tumour cells and/or by decreasing the exposure in normal host tissues. Therefore, Nano scale-based drug delivery through pH-sensitive Nano systems seem to be a boon for treating gynaecological cancers (as well as other cancers) without side-effects or with least harm to normal healthy tissues.
The Human Vaginal Microbiota: Boon or Bane
Authors: Gupta PD
Published: March 2021

We are soaked in microbiota, both, externally and internally. The balance between harmful and beneficial keeps us healthy, however even slight imbalance in their ratio may make cause of ill health. Many of the species of Lactobacillus keeps the vagina healthy; even some species of Lactobacillus are troublesome to the vagina. Other pathogenic bacteria and fungus cause many diseases. Lactobacillus spp prevents harmful bacteria to infect the vagina; nevertheless their population varies due to various factors mentioned in the text. Because of this the woman suffers even with infertility, abortions etc.
Mucocutaneous involvement in behçet’s disease
Authors: alaya Z
Published: March 2021

Behçet's disease is a chronic inflammatory disease characterized by its clinical polymorphism associating mucocutaneous involvement to systemic manifestations. The mucocutaneous lesions are considered the hallmark of the disease, being the most common symptoms presenting at the onset of disease. Our objective was to determine the characteristics of this skin involvement during Behçet's disease. We conducted a descriptive study over a period of 30 years, having collected all patients with Behçet's disease. These were 98 patients. A male predominance was observed in our studied population with a Sex Ratio of 2.5. The mean age at diagnosis was 34 years. Mucocutaneous involvement was observed in all patients. Oral aphthosis was constant and genital ulcers, were observed in 81 cases. The other mucocutaneous manifestations were: pseudofolliculitis (61 cases), erythema nodosum (7 cases), skin ulcers (4 cases), acneiform lesions (2 cases), perianal ulcers (1 case), skin ulceration (1 case) and erythema multiforme. (1 case). All of our patients were treated with colchicine. Corticosteroids and non-steroidal anti-inflammatory drugs were each indicated in one case for resistant forms.
PENGARUH PENERAPAN METODE KERJA KELOMPOK TERHADAP HASIL BELAJAR TARI TANGGAI PADA SISWA KELAS VIII DI SMP NEGERI 33 PALEMBANG
Authors: FARADILLAH DESY , HERA TRENY
Published: March 2021

ABSTRAKPenelitian ini membahas pengaruh penerapan metode kerja kelompok terhadap hasil belajar tari Tanggai. Penelitian ini bertujuan untuk mengetahui adakah pengaruh penerapan metode kerja kelompok terhadap hasil belajar tari Tanggai pada siswa kelas VIII di SMP Negeri 33 Palembang.Â Â Â Â Â Â Â Â Â Â Â  Metode penelitian yang digunakan dalam penelitian ini adalah metode eksperimen. Teknik yang digunakan dalam penelitian ini adalah Sampling Purposive yaitu teknik penentuan sampel dengan pertimbangan tertentu. Sampel dalam penelitian ini berjumlah 11 siswa laki-laki dan 20 siswa perempuan. Sebelum perlakuan metode pembelajaran yang digunakan yaitu metode demonstrasi, setelah perlakuan metode yang digunakan yaitu metode kerja kelompok. Teknik pengumpulan data menggunakan tes berupa tes unjuk kerja dan analisis data menggunakan Uji-t.Â Â Â Â Â Â Â Â Â Â Â  Berdasarkan hasil penelitian yang telah dilakukan oleh peneliti, didapatlah nilai Pre-test siswa dengan nilai rata-rata 68,3 dan nilai rata-rata Post-test siswa yaitu 85,2. Setelah memperoleh data hasil tes siswa, peneliti melakukan analisa data dengan menggunakan rumus Uji-t, diperoleh = 8,73 dan Â dengan taraf signifikan Â dan dk 30 diperoleh nilai Â = 2,04. Dengan demikian Â (8,73 Â yang berarti Ho ditolak dan Ha diterima. Dari hasil analisis data maka dapat disimpulkan bahwa adanya pengaruh penerapan metode kerja kelompok terhadap hasil belajar tari Tanggai pada siswa kelas VIII di SMP Negeri 33 Palembang.Â Kata Kunci : Pengaruh, Metode Kerja Kelompok, Hasil Belajar
PEMBELAJARAN TARI INDANG MENGGUNAKAN MODEL PEMBELAJARAN TUTOR SEBAYA KEPADA SISWA KELAS VIII SMP NEGERI 14 PALEMBANG
Authors: IRNAWILIS IRNAWILIS
Published: March 2021

ABSTRAKÂ Masalah dalam penelitian ini yaitu bagaimanakah pembelajaran Tari Indang dengan model pembelajaran tutor sebaya siswa kelas VIII di SMP Negeri 14 Palembang. Tujuan penelitian ini untuk mengetahui tentang bagaimana pembelajaran Seni Budaya dalam meningkatkan kemampuan menari Tari Indang dengan menggunakan metode tutor sebaya. Metode penelitian yang digunakan adalah deskriftifÂ  kualitatif, yang merupakan bentuk penelitian yang dilakukan peneliti dalam pembelajaran Tari Indang siswa kelas VIII dengan cara mengamati proses pembelajaran Tari Indang dan mendeskripsikannya. Teknik pengumpulan data dan analisis data yang digunakan adalah observasi, wawancara, dan dokumentasi. Hasil penelitian menunjukan bahwa berdasarkan hasil pembahasan, proses pembelajaran Seni Budaya dalam pembelajaran Tari Indang siswa kelas VIII di SMP Negeri 14 PalembangÂ Â  telah dilakukan sesuai dengan kurikulum/ silabus yang telah disesuaikan dengan keadaan siswa, meliputi tujuan, materi / bahan, metode, media, dan evaluasi pembelajaran. Pada hasil penelitian ,peneliti mengadakan penelitian selama waktu empat minggu dengan empat kali pertemuan. Penilaian yang dilakukan oleh guru mata pelajaran seni budaya dengan menggunakan penilaian praktik, hasil data siswa yang mencapai tuntas belajar nilai rata-rata 81 dengan kategori baik. Pada pelaksanaan penelitian di kelas VIII.1 SMP Negeri14 Palembang ini, kegiatan yang dilakukan meliputi: (a) perencanaan, (b) pelaksanaan, dan (c) evaluasi. Pembelajaran Tari Indang dilaksanakan di kelas VIII.1 SMP Negeri 14 Palembang dengan jadwal yang telah ditentukan oleh peneliti yaitu 4 kali pertemuan.Â Kata Kunci : Pembelajaran Tari Indang, Metode Tutor Sebaya
BENTUK PENYAJIAN TARI RODAT DI JAMAâ€™ATUL IHSAN 35 ILIR KOTA PALEMBANG
Authors: Sari Qumala
Published: March 2021

ABSTRAKÂ Masalah dalam penelitian ini adalah bagaimanakah bentuk penyajian tari Rodat di Jamaâ€™atul Ihsan 35 ilir kota Palembang. Tujuan penelitian ini untuk mengetahui dan mendeskripsikan bentuk penyajian tari Rodat di Jamaâ€™atul Ihsan 35 ilir kota Palembang. Metode penelitian yang digunakan adalah metode deskriptif kualitatif. Penelitian ini dilakukan di Jamaâ€™atul Ihsan 35 Ilir kota Palembang. Sumber data dalam penelitian ini adalah Kgs. Muhammad Azmi Makmur MA dengan menggunakan teknik pengumpulan data yaitu observasi, wawancara, dan dokumentasi. Teknik analisis data yang digunakan adalah reduksi data, sajian data dan penarikan kesimpulan. Hasil penelitian menunjukan bahwa Tari Rodat merupakan kesenian tari tradisional yang bernapaskan Islam, dimana tari ini digunakan untuk misi berdakwah dan menyebarkan agama Islam karena dalam tari ini terdapat syair-syair pujian kepada Allah Swt dan Rasul-Nya. Tari ini berkembang seiring dengan tradisi memperingati Maulid Nabi di kalangan umat Islam di kota Palembang. Tari Rodat ditarikan dengan Leyek (menari sambil duduk). Tari ini biasanya ditarikan oleh kaum laki-laki yang berdominan anak-anak remaja. Penari tari Rodat berjumlah 12 orang atau penarinya harus berjumlah genap. Sedangkan pemusik dalam tari Rodat terdapat tiga bagian yaitu: penabuh umak, penabuh ningka, pengiring ningka. Tari Rodat ini biasanya tergabung dalam PPSA (Perkumpulan Pelajar Syarofal Anam). PPSA Jamaâ€™atul Ihsan sudah ada sebelum Indonesia mendapatkan kemerdekaannya yang didirikan oleh yang biasanya disapa dengan Anang Bintang yang merupakan orang asli dari Palembang. Tari Rodat ditampilkan pada acara memperingati Maulid Nabi, acara khitanan, acara peresmian nama dan hari-hari besar Islam.Kata Kunci : Bentuk Penyajian, Tari Rodat,Palembang
PENGARUH FLUKTUASI HARGA EMAS, INFLASI, BI RATE DAN UKURAN PERUSAHAAN TERHADAP PEMBIAYAAN PRODUK GADAI EMAS BANK UMUM SYARIAH
Authors: Paleni Herman , Erfiani Mia
Published: March 2021

Islamic bank are bank that carry out business activites based on Islamic principles, namely agreements based on Islamic law between bank and   customers in accordance with Islamic law. The function of the bank is as an intermediary between people who are over-funded and those who are short of founds. There are many product channeling founds in Islamic banking one of which is gold mortgage financing. In 2012, golg mortgage financing experienced a very high increase but in 203 as slight decline until finally the decrease in the financing of the lowest gold mortgage that is in 2015. This is what makes the author interested to comply with the reduction of gold mortgage financing. The method of analysis used in this research is the method of panel data regression analysis done with Eviews 8. One of the requirements to perform multiple analysis test needs to be tested classical assumption. It is necessary that the resulting regression equation be BLUE (Best, Linear, Unbiased, Estimator). In addition to assess the goodness of fit a model tested coefficient of determination, F test, and t test. This study uses quarterly data from 20012-2018 for each research variable. The results of this study indicate that the variable gold price fluctuations, the BI Rate has a negative effect on the financing of gold pawning products and the inflation variable has an effect on the financing of the gold price variables and firm size have a positive effect on the financing of gold pawning products.