bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of the Faradarmani Consciousness Field on immune response induced by an inactivated vaccine against Foot and Mouth disease virus (FMDV) in rats and replication of FMDV in vitro
Authors: Taheri Mohammad Ali , Amani Laleh , Khalili Ahmad , Vaziri Ali Zaman , Keyvani Hossein
Published: September 2023

Foot-and-mouth disease (FMD) is one of the highest risk factors affecting the animal industry throughout the world. Currently, available commercial FMD vaccines have numerous limitations, such as slow induction and short-term maintenance of antibody titers. Therefore, a novel approach is needed that can induce high neutralizing antibody titers to protect the host in the early stages of FMD virus (FMDV) infection and maintain high antibody titers for long periods after one vaccination dose. There are several T-Consciousness Fields (TCFs), introduced by Mohammad Ali Taheri. TCFs are not matter or energy, so they cannot be measured directly. However, we can evaluate their effects indirectly through several reproducible experiments in the laboratory. The present study aimed to evaluate the effect of Faradarmani CF as a type of the TCFs on FMDV replication, titer, and RNA copy number as well as the humoral immune response against two types of inactivated FMDV vaccines with different adjuvants in rats. Two types of FMD vaccines with different adjuvants (Freund and Alum) were prepared, and then 30 male Wistar rats were immunized with vaccines. Rats were divided into 6 groups (n=5 per group). Four groups of rats were studied using the different combinations of treatments and two groups served as positive and negative controls. Vaccination intervals were every 14 days three times. Serum neutralization test (SN) and Enzyme-linked immunosorbent assay (ELISA) were used to assess changes in antibody levels in the serum samples of rats after each immunization. The results showed that Faradarmani CF induced the replication of the virus in vitro. In addition, antibody levels in treated groups under both Freund adjuvant and Alum adjuvant vaccines increased significantly compared to groups without Faradarmani CF treatment. In conclusion, our data suggest that Faradarmani CF may provide an effective approach to increase the success of immunization and vaccination against FMDV serotype O. It is recommended that the effects of TCFs on different types of vaccines be investigated.
Investigating the Effect of Taheri Consciousness Fields on the Behavior of the Laser Light in Passing through an Aperture and Observing the Heisenberg Uncertainty Principle
Authors: Taheri Mohammad Ali , Payervand Firouz , Ahmadkhanlou Farzad , Torabi Sara , Semsarha Farid
Published: September 2023

Investigating the behavior of light in the vicinity of an aperture and observingHeisenberg’s uncertainty is a classic experiment in optics. Studies of TaheriConsciousness Fields (TCFs)include the study of different fields of physicsin the systems under study. By applying a TCF to the system under thestudy, changes in the behavior of the system as a function of the Field areobserved. The present study was performed with two aims: (a) Investigationof the effect of TCFs on the pattern of the laser light diffraction through anaperture (in Fraunhofer diffraction patterns). (b) Investigation of the effect ofTCFs on the behavior of light and observation of Heisenberg’s uncertaintyprinciple in these conditions. Applying TCFs to the laser light-independentof the set-up experiment did not affect the light behavior. On the other hand,applying TCFs to the set-up of the light-passing test through an aperturehas a significant effect on the light behavior in passing through the aperture.In such a way, the uncertainty and diffraction width in the state of treatmentwith TCFs is reduced compared to the control. This behavior is interpreted asreducing the effect of the observer in optics studies, where the aperture hasbeen considered equivalent to an observer. In other words, this change in thelight behavior as a result of applying the TCFs can be considered a processof direct observation (without intermediaries) of the system under the studyusing the TCF. This study indicates the high potential of the effects of TCFson the known laws of physics, as an innovative tool in science.
The Examination of the Effect of Training Taheri Consciousness Fields, Faradarmani and Psymentology, on the Personality Features of the Clients in Erfane-Kamal Center in Tehran
Authors: Pedram nia Arezoo , Taheri Mohammad Ali , Haddad Monir
Published: September 2023

Faradarmani and Psymentology are two Iranian complementary medicines of applying Taheri Consciousness Fields (TCFs) in order to treat disturbances of human existential dimensions, founded and introduced by Mohammad Ali Taheri. In these methods, the relation between the partial and Whole (Cosmic) Intelligence, and consequently, the scan of the system under the study, is performed for repair, correction, and modification. The current research aimed to examine the effect of the Faradarmani and Psymentology training and their TCFs on the personality of the clients Erfane-Kamal center in Tehran. The quasi-experimental method with the pretest-post was utilized for 35 participants in the Erfane-Kamal center in Tehran (capital of Iran). The participants were simple-randomly selected from 100 persons who actively and voluntarily underwent the Faradarmani and Psymentology training courses, 56 sessions, twice a week for 120 minutes, including theoretical subjects and practical experience of its TCFs. The Cloninger’s Temperament and Character Inventory (TCI) were used to assess the personality changes triggered by/caused by training courses. To analyze the data, the Analysis of Variance (ANOVA) and SPSS software were utilized. The results demonstrated that except for the reward-dependence subscale, the Faradarmani and Psymentology training had a significant effect on participants’ personality features. The amount of k2 for subscales of self-transcendence, cooperation, self-directedness, vulnerability, and novelty-seeking were 0.54, 0.48, 0.46, 0.48, and 0.11, respectively. In conclusion, in the case of Faradarmani and Psymentology training courses that focus on enriching the worldviews of people, and providing them with the philosophy of human creation, it was anticipated that their worldviews regarding these topics would be corrected and modified after undertaking the courses, which become confirmed by the statistical results.
Investigating the effect of Taheri Consciousness Field A on the Behavior of Biomimetic Micellar Supramolecular Models
Authors: Taheri Mohammad Ali , Torabi Sara , Nabavi Noushin , Semsarha Farid
Published: September 2023

Supramolecular bio-mimicry models are aggregates of chemical components that have the ability to mimic the function of biological molecules. There are many applications for bio-mimicry models in the industry and other research fields. In basic biology, bio-mimicry models can help investigate vital behaviors and life-beginning forms. The effects of Taheri Consciousness Fields (TCFs) on different levels of life in living systems and non-living components such as metal elements have been studied and confirmed prior to this study. In the present research, we investigated the effect of a TCF on biomimetic models, as chemical structures with biologic-like behaviors, with the aim of understanding how vital behaviors are formed from basic chemical components giving rise to life. In this way, the effect of a type of TCF, named TCF (A), on the structure and function of biomimetic micellar supramolecular models mimicking enzyme behaviors was investigated. To mimic the behavior of heme proteins, such as horseradish peroxidase enzyme, this model contained sodium dodecyl sulphate (SDS) micelles body with histidinate hematin in its core. The results showed that TCF (A) does not change the chemical structure of the built-in biomimetic models. However, the predominant population of the sample model was observed to have a smaller particle size, unlike the untreated control. Additionally, the catalytic activity of the biomimetic sample model had an 8% increase in catalytic efficiency, which resembled the performance of the natural enzyme better than the untreated control. Moreover, zeta potential, conductivity, and mobility of the sample model under the influence of TCF (A) were changed by 40%-45% in comparison with the control. In conclusion, according to the results, the TCF (A) treatment made the micellar supramolecular biomimetic model more stable. It more resembles the structure and function of the colloidal solution with the biological molecules of living organisms.
The Structure and Function of Horseradish Peroxidase (HRP) under the Influence of Faradarmani Consciousness Field
Authors: Taheri Mohammad Ali , Torabi Sara , Nabavi Noushin , Semsarha Farid
Published: September 2023

The study of biological enzymes with their unique properties, such as substrate interactions, conformational changes, and catalytic rates, is a key to basic and applied enzymology research. Among enzymes, horseradish peroxidase (HRP) has been widely used in studying the metabolism of biological systems. In this study, we measure changes in the activity and structure of horseradish peroxidase in both laboratory grade and isoforms extracted from the plant under the influence of Faradarmani Consciousness Field (FCF). Our objectives were first to test the effect of FCF on the structure and function of HRP and, secondly, to analyze whether or not changes in the maximum velocity and Michaelis constant were reproducible under the influence of FCF. We observed that the laboratory-grade HRP had a 5% decrease in maximum velocity and an 18% increase in Michaelis constant as a result of the FCF treatment when compared to the non-treated controls. On the other hand, the HRP extracted from the plant tissue showed a 6% and 40% increase in maximum velocity and Michaelis constant, respectively, under FCF. Additionally, changes in the fluorescence emission intensity spectrum suggest that both structural and functional changes in this enzyme result from the FCF treatment.
Alleviative effects of Faradarmani Consciousness Field on Triticum aestivum L.under salinity stress
Authors: Torabi Sara , Taheri Mohammad Ali , Semsarha Farid
Published: September 2023

Previously, the effects of the Faradarmani Consciousness Field on common wheat Triticum aestivum L. var Star under salts tress was investigated, and chlorophyll, hydrogen peroxide (H2O2), malondialdehyde (MDA) content, and activity of antioxidant enzymes, such as superoxide dismutase (SOD), polyphenol oxidase (PPO), and peroxidase (POX) were measured in all groups of plants. The results showed that in the salt-treated plants under the influence of Faradarmani CF, the contents of total chlorophyll, as well as a and b chlorophyll forms, were elevated compared with the salt-treated plants without Faradarmani CF (34.8%, 17.8%, and 169% respectively). Additionally, Faradarmani increased H2O2 (57%) and the activity of SOD and PPO by 220% and 168%, respectively, under salinity compared with the salt-treated plants without Faradarmani CF. MDA content and activity of peroxidase were decreased by 12.5% and 34%, respectively. In conclusion, these results suggest the Faradarmani CF as a qualitative strategy to withstand salt stress in plants by increasing the contents of chlorophyll, antioxidant enzyme activities, and decreasing MDA content under salinity.
Torabi S, Taheri, M. A, & Semsarha F. (2021). Alleviative effects of Faradarmani Consciousness Field on Triticum aestivum L.under salinity stress [version 3; peer review: 1 approved]. F1000Research, 9, 1089 (https://doi. org/10.12688/f1000research.25247.3)
Effect of Taheri Consciousness Bond Field on the Structure and Properties of 1000-Series Aluminum with Preheating
Authors: Kazazi Bahareh , Taheri Mohammad Ali
Published: September 2023

The properties and structure of aluminum in various known fields have already been studied. The aim of this study was to investigate the behavior and properties of unalloyed aluminum with 300 °C preheating under the Consciousness Bond Field. Taheri Consciousness Fields (TCFs) were founded and introduced by Mohammad Ali Taheri as new Fields more than four decades ago. These Fields are neither material nor energetic. Therefore, they do not have the quantity, but they have direct effects on both matter and energy. In other words, although TCFs cannot be directly measured, we can investigate their effects indirectly through various reproducible experiments. The present study is an attempt to examine this theory. For this purpose, aluminum metal was used as a sample. Six aluminum samples were cast under the same conditions and divided into two groups. One group was put under the influence of TCF, and the other group was the control. Then, in order to record the effect of the Consciousness Bond Field, the structure and properties of the metal samples were investigated. X-ray diffraction (XRD) analysis was performed for structural analysis of the samples. In terms of properties, corrosion resistance was investigated in a standard SBF solution. Some changes in the structure, such as reduction of twin defects and increase of extrinsic and intrinsic defects were observed under the influence of TCF.
The Word’s Unity of Existence
Authors: Rezaie Naghmeh , Taheri Mohammad Ali
Published: September 2023

Linguists do not agree on the origin of human language or the reasons for the human species’ unique possession of language faculty on the path of evolution. Any theoretical approach in cognitive science and linguistics eventually faces an impasse in its quest for the origin of language when reaching the realm of consciousness and mind which requires an accessibility beyond the physical inquiry. This article introduces Mohammad Ali Taheri’s theory of consciousness, T-Consciousness, as the gateway to the origin of language in the human mind. T-Consciousness stands for the non-material and non-energetic constituent of the universe, the third fundamental element which generates both matter and energy. Taheri theorizes that human beings have detected language rather than inventing it, following the Language Software’s primary activation in the human mind through an inter-T-Consciousness-level connection that extracts Fara-lingual information and adapts it into language. This study investigates Taheri’s language theory in relation to Chomsky’s UG theory, and offers a diversifying approach to UG theory, biolinguistics and psycholinguistics. The article introduces the Word’s Unity of Existence/ Vahdat-e Vojood-e Kalameh and conceptualizes the Unified Body of Languages, initiating an interdisciplinary discourse to revisit cognitive science, phenomenology, hermeneutics, and intertextuality.
Marriages of More Than Four and its Impacts on Community Perspective of Islamic Law and Indonesian Law
Authors: Muhammad Thaib Yahya , Mahmoud ELSakhawy Rania , Muthoifin Muthoifin , Al-Mutawakkil Thufail
Published: September 2023

The objectives of the research are to find out the ruling on the marriage of more than four women under the bondage of a man according to Islamic jurisprudence and law in Indonesia, and to know the sayings of scholars about the multiple women of more than four and to know the dispute between them and the most correct of their sayings. The way of thinking in this research is qualitative research, where the researcher focuses on studying the process using inductive and comparative inferential. In this research, the type of research used a desk approach. Marriage of more than four women is forbidden according to the texts of the Qur’an and Sunnah. And it is proven that the Messenger of God, upon him be peace, commanded those who work together with more than four women by separating from some of their wives so that the number of their wives is four. He did not lay down the statutory laws about marrying more than four women but was mentioned in the fatwas of Indonesian scholars. The fatwa from the Council of Scholars Indonesia and the group of proposals in Indonesian Islamic rulings saw the prohibition of marriage with more than four women. It was reported by some scholars that they permitted it, and it is the most likely view. He who marries more than four women according to Islamic jurisprudence, knowing the prohibition, has committed adultery and has the punishment for stoning, and the fifth child is attached to his mother, not to his father.
Premeditated Murder in the Modern Era Comparative Study of Perspectives on Islamic Law and the Criminal Code
Authors: Oktatianti Tina , Mubarak Bin Humaid Mahmoud Saleh , Irfan Rosyadi Rozi , Abdul Adzim Ahmadi , Muthoifin Muthoifin
Published: September 2023

This study tries to 1) identify the elements that lead murderers to plan their crimes, and 2) understand those elements. The judge's factors to consider when determining murder cases with intent to kill, 3). Comparing the Criminal Code with Islamic law's definition of premeditated murder. To gather data for this study, a library research technique known as a normative juridical approach to literature evaluation was used. The Criminal Code, followed by the Koran, Hadith, and translations into Indonesian, as well as relevant scholarly works, books, and articles, served as the source for legal information. The study's findings led to the conclusion that Indonesian law's Criminal Code Articles 338–350 govern the crime of murder. In the Criminal Code, premeditated murder is defined as a purposeful killing, whereas in Islamic criminal law, the victim's life is the first thing that is intended to be taken. According to Article 340 of the Criminal Code, the perpetrator of a premeditated murder may be sentenced to life in prison by a jury of judges. Whereas in Islamic criminal law, as mentioned in QS. Al-Maidah verse 45 and Hadith, the perpetrator's acts might result in a death sentence (Qishash) for committing purposeful murder.
China and the Republic of Zimbabwe: the main areas of cooperation.
Authors: Smirnova Ekaterina Borisovna
Published: September 2023

After sanctions in the 2000s were imposed, the cooperation with China that helped Zimbabwe to cope with the crisis at home and on the international arena. The object of research in this paper is the Sino-Zimbabwean relations. The subject of the study is the interaction and cooperation between China and Zimbabwe in politics and economics in the period 2000-2019. The purpose of the study is to assess the main areas of Chinese–Zimbabwean cooperation in 2000-2019. The author examines the evolution of interaction in the political and economic sphere between China and Zimbabwe, identifies the factors that influenced cooperation in these areas. The novelty of this study lies in a comprehensive assessment of the development trend of Chinese-Zimbabwean cooperation in the field of politics and economics in the period 2000-2019. The systematic method allowed us to consider the trend of cooperation in the field of politics and economics between the PRC and the Republic of Zimbabwe on the basis of extensive use of sources. The author concludes that cooperation between China and Zimbabwe is important in the context of the foreign policy of both countries. This multifaceted alliance in the political and economic spheres contributes to the development and strengthening of diplomatic ties, which have an impact on the common prosperity of both countries.
Methodological and theoretical foundations of therapy with metaphorical associative cards
Authors: Aksyutina Zul'fiya Abdullovna
Published: September 2023

Metaphorical associative cards have become a popular tool in art therapy for children and adults, which is the reason and the need for their careful study. The subject of the analysis is the methodological and theoretical foundations of the use of metaphorical associative maps. The purpose of the article is to identify methodological and theoretical grounds for the use of metaphorical associative maps. The research methods used are the analysis of scientific publications and methods of categorical-system methodology (universal scheme of interaction and the method of categorical pendulum). The article substantiates the place of metaphorical associative maps in psychotherapy, searches for theoretical grounds for the implementation of psychotherapeutic procedures related to metaphorical associative maps. Based on the idea expressed by N. V. Dmitrieva, Yu. M. Perevozkina, L. V. Levina and N. V. Buravtsova, an evidence-based analysis of the characteristic features of attributing metaphorical associative maps to the section of expressive psychotherapy, a subclass of creative therapy and a class of art therapy is carried out. The methodological components of its qualitative states (object, subject and goal) in system, process and activity variations are revealed in the theoretical justification of MAC therapy based on the reliance on system and activity approaches. The study of MAC therapy as a dynamic system allowed us to conclude that the result of interaction depends on the creative potential of the client, which indicates possible limitations in the use of metaphorical associative maps. The construction of a system model of MAC therapy allowed us to identify the basic conceptual apparatus of this field of psychotherapy. The obtained results of the theoretical study will be useful in the practice of providing assistance during psychotherapeutic procedures using metaphorical associative maps.
Methods of psychotherapeutic correction of the emotional state of drug addicts in the process of treatment and rehabilitation measures
Authors: Rublyova Tatiana , Lisnyak Marina
Published: September 2023

The research is devoted to the study of the emotional sphere of psychoactive substance users at the stage of rehabilitation. The aim of the study is to compare the content and dynamic characteristics of the emotional state of patients with chemical dependence who receive and do not receive psychotherapeutic help. Subject of research: the possibility of correcting the emotional state of drug addicts through the use of art therapy methods. Experimental research base: rehabilitation center (Krasnoyarsk). Experimental sample of the study: 24 drug-addicted men aged 25 to 40 years. Research methods: the study of the locus of control of J. The study of the level of anxiety (the scale of C.D. Spielberger, Y.L. Khanin); the Rosenzweig test "The technique of pictorial frustration"). Data processing was carried out using the program "SPSS Statistics 21". The reliability of the differences between the indicators in the experimental group and the comparison group was calculated using the U-Mann-Whitney criterion for independent samples. The results of the study showed that a psychocorrection program with elements of art therapy can relieve emotional tension, reduce anxiety and frustration. In addition, the shift of the locus of control towards the internal type contributes to an increase in the level of responsibility for one's own actions and a decrease in the level of aggressiveness. And increasing the level of social adaptation improves interaction within the group, which leads to a decrease in the number of external and internal conflicts. Additionally, patients' motivation for recovery increases due to the support of the group, which is very important for the effective and successful completion of the rehabilitation program. The obtained data and the proposed psychocorrection program can be used by medical psychologists in working with drug-dependent patients to correct their emotional state during treatment and rehabilitation measures.
Get the gist of the story: Neural map of topic keywords in multi-speaker environment
Authors: Park Hyojin , Gross Joachim
Published: September 2023

Neural representation of lexico-semantics in speech processing has been revealed in recent years. However, to date, how the brain makes sense of the higher-level semantic gist (topic keywords) of a continuous speech remains mysterious. Capitalizing on a generative probabilistic topic modelling algorithm on speech materials to which participants listened while their brain activities were recorded by Magnetoencephalography (MEG), here we show spatio-temporal neural representation of topic keywords in a multi-speaker environment where task-relevant (attended) and -irrelevant (unattended) speech co-exits. We report the difference of neural representation between salient and less salient semantic gist of both attended and unattended speech. Moreover, we show that greater sensitivity to semantically salient unattended speech in the left auditory and motor cortices negatively mediates attended speech comprehension.
Truncated radial glia as a common precursor in the late corticogenesis of gyrencephalic mammals
Authors: Bilgic Merve , Wu Quan , Suetsugu Taeko , Shitamukai Atsunori , Tsunekawa Yuji , Shimogori Tomomi , Kadota Mitsutaka , Nishimura Osamu , Kuraku Shigehiro , Kiyonari Hiroshi , Matsuzaki Fumio
Published: September 2023

The diversity of neural stem cells is a hallmark of the cerebral cortex development in gyrencephalic mammals, such as Primates and Carnivora. Among them, ferrets are a good model for mechanistic studies. However, information on their neural progenitor cells (NPC), termed radial glia (RG), is limited. Here, we surveyed the temporal series of single-cell transcriptomes of progenitors regarding ferret corticogenesis and, found a conserved diversity and temporal trajectory between human and ferret NPC, despite the large timescale difference. We found truncated RG (tRG) in ferret cortical development, a progenitor subtype previously described in humans. The combination of
in silico
and
in vivo
analyses identified that tRG differentiate into both ependymal and astrogenic cells. Via transcriptomic comparison, we predict that this is also the case in humans. Our findings suggest that tRG plays a role in the formation of adult ventricles, thereby providing the architectural bases for brain expansion.
Geotricosis: fungemia en paciente con leucemia linfoblástica aguda
Authors: Álvarez-Rodríguez José Camilo , Blanco-Bustos María Paula , Cuervo-Maldonado Sonia Isabel , Gómez-Rincón Julio César , Reyes Ángela
Published: September 2023

La fungemia por Geotrichum spp. es poco frecuente y altamente letal. En el Instituto Nacional de Cancerología de Bogotá solo se han reportado dos casos: uno entre el 2001 y el 2007, y el otro entre el 2012 y el 2018. Este tipo de infección es más común en pacientes con algún grado de compromiso del sistema inmunitario, por lo que puede presentarse en pacientes con neoplasias hematológicas malignas.Se presenta el caso de un hombre de 27 años con recaída de leucemia linfoblástica aguda, que ingresó con poliartralgias de cinco días de duración. También cursaba con neutropenia febril, celulitis sin abscesos y bacteriemia por Staphylococcus aureus resistente a la meticilina para lo cual recibió terapia con oxacilina y cefepime. Sin embargo, persistía la neutropenia febril por lo que se sospechó una infección fúngica invasora. Se tomó un nuevo set de hemocultivos y se inició tratamiento antifúngico.En los hemocultivos se identificaron artroconidias y mediante espectrometría de masas por láser de matriz asistida de ionización-desorción se confirmó la presencia de Geotrichum spp. Se ajustó el tratamiento antifúngico con deoxicolato de anfotericina B por 14 días y voriconazol por cuatro semanas. Luego de una estancia prolongada se le dio de alta.Aunque la incidencia de la fungemia por Geotrichum spp. es baja, en pacientes con neoplasias hematológicas malignas debe considerarse en el contexto de una neutropenia febril que es persistente a pesar del tratamiento antimicrobiano de amplio espectro.
La importancia de la correlación clínico-epidemiológica en el diagnóstico temprano de la histoplasmosis: reporte de dos casos clínicos en Popayán, Colombia
Authors: Potosí Jorge Andrés , Gutiérrez Yina Marcela , González Fabiola Eugenia
Published: September 2023

La histoplasmosis es una micosis endémica en Colombia. Se presentan dos casos del departamento del Cauca, para mostrar el impacto clínico que conlleva un retraso en su diagnóstico y tratamiento. Se obtuvo el consentimiento informado para revisar las historias clínicas de los pacientes y publicar los casos.El primer caso se trata de un paciente con infección por el virus de inmunodeficiencia humana (Human Immunodeficiency Virus, HIV), quien presentaba lesiones cutáneas generalizadas atribuidas inicialmente al virus del herpes; post mortem y mediante el cultivo para hongos de muestras de las lesiones dérmicas, se confirmó el diagnóstico de histoplasmosis. El segundo caso es un paciente inmunocompetente con sintomatología pulmonar, a quien se le diagnosticó tuberculosis clínicamente y se le instauró tratamiento; sin embargo, ante la nula mejoría y teniendo en cuenta el antecedente de ingreso a una cueva de murciélagos, se enfocó como una posible histoplasmosis pulmonar y se obtuvo mejoría con el tratamiento.Se revisó la literatura sobre las pruebas de laboratorio y los datos epidemiológicos de histoplasmosis que deben considerar los profesionales de la salud. Se concluyó que las instituciones de salud deben disponer de pruebas rápidas (por ejemplo, antigénicas) para el diagnóstico y tratamiento adecuado de esta micosis, además de adoptar los correctivos necesarios para minimizar la exposición a Histoplasma.
Phenotypic and genotypic characterization of Colombian clinical isolates of Sporothrix spp.
Authors: Álvarez-Acevedo Laura C. , Zuleta-González María C. , Gómez-Guzmán Óscar M. , Rúa-Giraldo Álvaro L. , Hernández-Ruiz Orville , McEwen-Ochoa Juan G. , Urán-Jiménez Martha E. , Arango-Arteaga Myrtha , Zancopé-Oliveira Rosely M. , Evangelista de Oliveira Manoel Marques , Jiménez-Alzate María del P.
Published: September 2023

Introduction. For over a century, Sporothrix schenckii was considered the sole species responsible for sporotrichosis. In 2007, scientific community confirmed the disease could be caused by various Sporothrix species. These species differed in their virulence factors and their antifungal sensitivity.Objective. This study aims to characterize 42 Colombian clinical isolates of Sporothrix spp. phenotypically and genotypically.Material and methods. Forty-two clinical isolates were characterized using phenotypic methods. It involved various culture media to determine their growth range at different temperatures and to assess the type and distribution of pigment and colony texture. Microscopic morphology was evaluated through microcultures, as well as the conidia diameter, type of sporulation, and morphology. Additionally, the assimilation of carbohydrates was selected as a physiological trait for species identification. Genotyping of 40 isolates was performed through partial amplification of the calmodulin gene, followed by sequence analysis.Results. Molecular studies enabled the identification of 32 isolates of S. schenckii and 8 isolates of S. globosa. The combination of phenotypic and genotypic methods eased these species characterizations and the recognition keys development based on parameters such as growth diameter at 25 and 30 ºC, colony texture (membranous or velvety) on potato dextrose agar, and microscopic morphology with predominance of pigmented triangular, elongated oval globose, or subglobose conidia.Conclusions. Confirmation of the phenotypic characteristics and molecular analysis is crucial for identifying Sporothrix species and determining adequate treatment. This study represents the first phenotypical and genotypical characterization of clinical isolates of Sporothrix spp. reported in Colombia.
Hiperplasia pseudoepiteliomatosa: carcinoma escamocelular versus paracoccidioidomicosis oral, un caso con mirada dermatológica
Authors: Osorio-Cock Lina M. , Jaramillo-Pulgarín Sandra Catalina , Ferrín-Bastidas Alba P. , Molina-Colorado Diana Y. , Gómez-Guzmán Óscar M. , Zuluaga Alejandra , McEwen-Ochoa Juan G. , Urán-Jiménez Martha E. , Jiménez-Alzate María del Pilar
Published: September 2023

La paracoccidioidomicosis es una micosis sistémica endémica en Latinoamérica. La presentación más frecuente compromete crónicamente los pulmones, la piel y las mucosas. Al inicio, este paciente presentó, por varios años, una lesión única en la mucosa oral que, en ausencia de otros síntomas, se relacionó con una neoplasia maligna, específicamente con un carcinoma escamocelular.La diferenciación entre los dos diagnósticos se hace mediante un examen directo, un estudio histopatológico y cultivos iniciales y subsecuentes. Sin embargo, tales estudios no fueron concluyentes. Después de varias consultas y pruebas, con los resultados del examen directo, la inmunodifusión y la PCR en tiempo real se confirmó el diagnóstico de paracoccidioidomicosis crónica multifocal.Este caso alerta sobre la ausencia de sospecha clínica de micosis endémicas, dada la presencia de lesiones mucocutáneas que pueden ser producidas por hongos como Paracoccidioides spp, y la importancia de considerarlas entre los diagnósticos diferenciales.
Brote de tinea capitis y otras micosis superficiales en una comunidad urbana de Medellín
Authors: Sterling Nelson Andrés , Rincón Duban Andrés , Barrera Sebastián , Sánchez Erika Andrea , Molina Diana Yuledi , Urán Martha Eugenia , Jiménez María del Pilar
Published: September 2023

Introducción. Las dermatofitosis son infecciones fúngicas superficiales de epitelios queratinizados. La tinea capitis es una de ellas y afecta a poblaciones escolares vulnerables. Carpinelo es un barrio del área periférica de Medellín con precarias condiciones socioeconómicas. Ante la sospecha de un brote de dermatofitosis, losafectados fueron evaluados.Objetivo. Evaluar clínica y microbiológicamente pacientes del barrio Carpinelo con sospecha de micosis cutáneas para determinar la presencia de un brote por dermatofitos.Materiales y métodos. Se llevó a cabo un estudio descriptivo, de corte longitudinal, con muestreo a conveniencia. Se hizo una búsqueda activa de casos en el Jardín Educativo Buen Comienzo de Carpinelo en niños de la institución y sus familiares. Se evaluaron clínicamente y se tomaron muestras de escamas y cabellos para exámenes directos y cultivos microbiológicos. Se analizó el perfil demográfico, clínico y micológico, con el programa estadístico SPSS™, versión 25.Resultados. Se estudiaron 57 pacientes, 47 eran menores de edad con una media de edad de seis años; se observó una proporción de hombres y mujeres de 2:1. Los pacientes con resultados positivos se diagnosticaron con tinea capitis (78,95 %), tinea faciei (15,79 %) y tinea corporis (10,52 %). El 75,43 % de los pacientes recibió tratamiento previo y de estos el 69,73 % fue con esteroides. El examen directo fue positivo en el 53,84 % y los cultivos en el 46,5 % de los casos. Los agentes aislados fueron: Microsporum canis (77,77 %), Trichophyton spp. (11,11 %), Trichophyton rubrum (5,55 %) y Malassezia spp. (5,55 %).Conclusión. Tinea capitis fue la presentación clínica más común y M. canis el dermatofito más frecuentemente aislado. Llamó la atención el uso de esteroides como primera y única opción del tratamiento empírico‚ lo cual resalta la importancia del diagnóstico microbiológico para proporcionar la terapia apropiada.
Fusariosis en pacientes con cáncer: serie de 13 casos y revisión de la literatura
Authors: Cuervo-Maldonado Sonia Isabel , Álvarez-Rodríguez José Camilo , Cubides Cristian Leonardo , Barrera Juan Camilo , Montañez-Abril Juan Diego , Vergara-Vela Erika Paola , Saavedra-Trujillo Carlos Humberto , López-Mora María José , Mora-Figueroa Gloria Elena , Celis-Ramírez Adriana , Jaramillo-Calle Rose Mary , Parra-Medina Rafael
Published: September 2023

La fusariosis es una micosis oportunista producida por Fusarium spp. Su presentación clínica depende del estado inmunológico del huésped, especialmente, el de aquellos con enfermedades hematooncológicas, cuyas manifestaciones varían desde formas localizadas hasta infección fúngica invasora. El cultivo de piel o de sangre permite orientar el tratamiento antifúngico combinado con anfotericina B y voriconazol.Se presentan 13 casos de pacientes con cáncer en un periodo de once años que desarrollaron fusariosis diseminada; asimismo, se hizo con una revisión extensa de la literatura.En esta serie de casos, la mortalidad fue del 61,5 % (8/13), a pesar del uso del antifúngico. De los 13 pacientes, 11 tenían neoplasia hematológica y 2 neoplasia sólida. El factor de riesgo más importante fue la neutropenia profunda. El compromiso de la piel y los hemocultivos positivos facilitaron la prescripción del tratamiento combinado en la mayoría de los casos. La neutropenia febril persistente asociada a lesiones cutáneas, la onicomicosis, los nódulos o las masas pulmonares permitieron sospechar una infección fúngica invasora por Fusarium spp.El objetivo de la presentación de esta serie de casos es recordar el diagnóstico de fusariosis a la comunidad médica en contacto con pacientes oncológicos, con neutropenia febril profunda y persistentes.
Taxonomía de los hongos: un rompecabezas al que le faltan muchas piezas
Authors: Rúa-Giraldo Álvaro León
Published: September 2023

Los hongos son organismos polifacéticos presentes en casi todos los ecosistemas de la tierra, donde establecen diversos tipos de simbiosis con otros seres vivos. A pesar de ser reconocidos por los humanos desde la antigüedad –y de la cantidad de trabajos que han profundizado sobre su biología y ecología–, aún falta mucho por conocer sobre estos organismos.Algunos de los criterios que clásicamente se han utilizado para su estudio, hoy resultan limitados y hasta cierto punto permiten un agrupamiento de los aislamientos según algunas características, pero generan confusión en su clasificación y, más aún, cuando se pretende comprender sus relaciones genealógicas.Los caracteres fenotípicos no son suficientes para identificar una especie de hongos y, menos aún, para construir una filogenia amplia o de un grupo particular. Hay grandes vacíos que hacen que los árboles generados sean inestables y fácilmente debatidos.Para los profesionales de la salud, parece que la identificación de los hongos hasta niveles inferiores como género y especie es suficiente para elegir el tratamiento más adecuado para su control, comprender la epidemiología de los cuadros clínicos asociados y reconocer los brotes y los factores determinantes de la resistencia a los antimicrobianos. No obstante, la ubicación taxonómica dentro del reino permitiría establecer relaciones filogenéticas entre los taxones fúngicos, facilitando la comprensión de su biología, su distribución en la naturaleza y la evolución de su potencial patogénico.
Description of a common stauromedusa on the Pacific Coast of the United States and Canada, Haliclystus sanjuanensis new species (Cnidaria: Staurozoa)
Authors: Mills Claudia E. , Westlake Hannah , Hirano Yayoi M. , Miranda Lucília S.
Published: September 2023

Haliclystus “sanjuanensis” nomen nudum is the most common staurozoan on the west coast of the United States and Canada. This species was described in the M.S. Thesis by Gellermann (1926) and although that name has been in use nearly continuously since that time, no published description exists. Furthermore, the most popular operative name for this species has varied between several related species names over time, resulting in confusion. Herein, we provide a detailed description and synonymy of Haliclystus sanjuanensis n. sp., whose distribution is verified from Unalaska Island in the Aleutians (53.4° N, 166.8° W) in the northwest, to Santa Barbara County, California, just north of Point Conception (34.5° N, 120.5° W), in the south. Haliclystus sanjuanensis n. sp. is compared with the twelve other described species of Haliclystus and illustrations of both macroscopic and microscopic anatomy are provided. Haliclystus sanjuanensis n. sp. is unique among species of Haliclystus in the arrangement of the bright-white nematocyst spots in its calyx and the pattern of dark stripes running the length of the stalk and up the outside of the calyx.
Análise de indicadores classe mundial na manutenção numa máquina automática de calibração de corrente e gravação de firmware na placa de controle de bateria de celular
Authors: De Alencar Siomar Gonçalves , Cisneros Edry Antonio Garcia , Torné Israel Gondres , Silva Marcio Fabio dos Anjos , Lima Wellyngton Araujo , De Sousa Marcio Rizonildo Aquino , De Araujo Nelson Michel Matos , Seppe Fabricio Ribeiro , Da Silva Heitor Lifsitch Nogueira
Published: September 2023

A manutenção tem a função de assegurar que todos os ativos de uma empresa cumpram e continuem cumprindo as funções para as quais foram especificadas. Para a Associação de Normas Técnicas – ABNT (1994) a manutenção é “A combinação de todas as ações técnicas e administrativas, incluindo as de supervisão, destinadas a manter ou recolocar um item em um estado no qual possa desempenhar uma função requerida”. Nestes tempos onde a chamada indústria 4.0 impõe grandes retos em termos de acompanhamento e controle em tempo real dos processos produtivos visando o incremento da produtividade com os mínimos custos possíveis a manutenção de equipamentos constitui hoje em dia uma das atividades de grande relevância, visto que través da mesma e que se logra manter os equipamentos prontos para produzir e justamente o uso de indicadores possibilita de forma objetiva esse acompanhamento. No presente trabalho é apresentada o resultado da análise da manutenção de um equipamento usado numa fábrica do Polo Industrial de Manaus, baseado n uso de alguns dos indicadores classe mundial é possível chegar a métricas reais sobre o comportamento do mesmo num período aproximado de e meses. Os resultados obtidos validam a importância do uso destes indicadores no gerenciamento da manutenção no entrono da indústria 4.0.
Developing spinal manipulation psychomotor skills competency: A systematic review of teaching methods
Authors: de Kock Eleanor , Yelverton Christopher , Myburgh Cornelius
Published: September 2023

Objective

To update the state of the art regarding the acquisition of spinal high-velocity low-amplitude psychomotor skills competency among chiropractors and chiropractic students.

Methods

Available electronic articles from 5 databases, published between June 2015 and August 2020, were obtained. Eligible studies underwent methodological quality assessments using the Joanna Briggs Institute Critical Appraisal Checklists and Cochrane Collaboration's Risk of Bias Tools.

Results

Fourteen critically appraised studies were identified, including 10 cohort studies and 4 randomized controlled trials. There was no literature excluded due to high risk of bias. The type of augmented devices included a mannequin on a force platform, a computer-connected device, a human analogue mannequin, and a 3-dimensional electrogoniometer with an instrumented spatial linkage.

Conclusion

The use of augmented feedback devices such as human analogue mannequins with force-sensing table technology and computer-connected devices is potentially beneficial in the chiropractic curricula and may facilitate student learning and improvement of spinal manipulation. More studies are required to determine whether psychomotor skill aids translate directly into raised competency levels in novice clinicians.
Challenges Faced by International Students in Pursuing Doctoral Study: A Case Study of Saudi Students in American Higher Education Programs
Authors: Khawaji Ahmed
Published: September 2023

Many international students aspire to seek admission to higher education and pursue their studies, especially in the US. Therefore, institutions in general and American institutions in particular must realize the students' perspectives and offer support so they can face their unique problems during their education. This review aims to look into specific learning and adaptation-related experiences of international higher education students during a challenging transition to a large, public research university in the United States. The study was conducted at an American university in the southwest. The program enrolls students worldwide seeking master's and doctoral degrees in languages and social studies. Students may select from a wide range of concentrations, such as teaching English as a Second Language, bilingual education, and social justice, to name a few. These students are often encouraged to study interdisciplinary subjects to improve their understanding of the realm of education and how it is affected by society and politics. Professors teaching these interdisciplinary subjects who descend from various countries and teach in multiple disciplines hold controversial and sometimes even contradicting visions on education and research issues. This review explored the challenges and problems that Saudi international students face while pursuing higher education. A qualitative data collection and analysis method was followed to arrive at conclusions. 6 Saudi students were interviewed in detail. Study findings revealed various academic, social, cultural, financial, and family implications. It is concluded that Saudi international students encounter specific difficulties in US institutions, such as mentoring hardships, adjustment to a new educational system, lack of administrative support, and communication gaps between the supervisors and the researchers.
Pre-concept Inquiry of "Matter State Changes" in Junior High School Science
Authors: Zheng Fenfen , Zhang Yiping
Published: September 2023

The junior high school science course is a subject closely related to the reality of life, and before starting the formal learning of science concepts, students have formed many pre-concepts, which play a very important role in the formation of science concepts. In junior high school science teaching, it is necessary to explore students' relevant pre-concepts and the reasons for their formation, so that appropriate transformation strategies can be adopted to enable students to deeply understand science concepts, which is conducive to improving the effectiveness of science teaching. In this paper, a questionnaire survey was conducted to understand the pre-concepts embedded in students' minds before they learn the content related to matter state changes in junior high school science, and the reasons for the formation of erroneous pre-concepts were analyzed. In general, the formation of students' pre-concepts first comes from their own life experience and intuitive feelings, and is preceded by common sense of life. Second, through their own intuitive reasoning, they make wrong speculations about nouns. By identifying students' existing correct and wrong pre-concepts, it provides a basis for transforming vague and wrong pre-concepts in students' minds into science concepts in the subsequent teaching design.