bluuebunny/crossref_metadata_2025 huggingface dataset:
Cultural Familiarity and Individual Musical Taste Differently Affect Social Bonding when Moving to Music
Authors: Stupacher Jan , Witek Maria A. G. , Vuoskoski Jonna K. , Vuust Peter
Published: June 2020

Social bonds are essential for our health and well-being. Music provides a unique and implicit context for social bonding by introducing temporal and affective frameworks, which facilitate movement synchronization and increase affiliation. How these frameworks are modulated by cultural familiarity and individual musical preferences remain open questions. In three experiments, we operationalized the affective aspects of social interactions as ratings of interpersonal closeness between two walking stick-figures in a video. These figures represented a virtual self and a virtual other person. The temporal aspects of social interactions were manipulated by movement synchrony: while the virtual self always moved in time with the beat of instrumental music, the virtual other moved either synchronously or asynchronously. When the context-providing music was more enjoyed, social closeness increased strongly with a synchronized virtual other, but only weakly with an asynchronized virtual other. When the music was more familiar, social closeness was higher independent of movement synchrony. We conclude that the social context provided by music can strengthen interpersonal closeness by increasing temporal and affective self-other overlaps. Individual musical preferences might be more relevant for the influence of movement synchrony on social bonding than musical familiarity.
Two novel fish paralogs provide insights into the Rid family of imine deaminases active in pre-empting enamine/imine metabolic damage
Authors: Digiovanni Stefania , Visentin Cristina , Degani Genny , Barbiroli Alberto , Chiara Matteo , Regazzoni Luca , Di Pisa Flavio , Borchert Andrew J. , Downs Diana M. , Ricagno Stefano , Vanoni Maria Antonietta , Popolo Laura
Published: June 2020

Reactive Intermediate Deaminase (Rid) protein superfamily includes eight families among which the RidA is conserved in all domains of life. RidA proteins accelerate the deamination of the reactive 2-aminoacrylate (2AA), an enamine produced by some pyridoxal phosphate (PLP)-dependent enzymes. 2AA accumulation inhibits target enzymes with a detrimental impact on fitness. As a consequence of whole genome duplication, teleost fish have two ridA paralogs, while other extant vertebrates contain a single-copy gene. We investigated the biochemical properties of the products of two paralogs, identified in Salmo salar. SsRidA-1 and SsRidA-2 complemented the growth defect of a Salmonella enterica ridA mutant, an in vivo model of 2AA stress. In vitro, both proteins hydrolyzed 2-imino acids (IA) to keto-acids and ammonia. SsRidA-1 was active on IA derived from nonpolar amino acids and poorly active or inactive on IA derived from other amino acids tested. In contrast, SsRidA-2 had a generally low catalytic efficiency, but showed a relatively higher activity with IA derived from L-Glu and aromatic amino acids. The crystal structures of SsRidA-1 and SsRidA-2 provided hints of the remarkably different conformational stability and substrate specificity. Overall, SsRidA-1 is similar to the mammalian orthologs whereas SsRidA-2 displays unique properties likely generated by functional specialization of a duplicated ancestral gene.
Early-onset atrial fibrillation patients show reduced left ventricular ejection fraction and increased atrial fibrosis
Authors: Andreasen Laura , Bertelsen Litten , Ghouse Jonas , Lundegaard Pia R. , Ahlberg Gustav , Refsgaard Lena , Rasmussen Torsten B. , Eiskjær Hans , Haunsø Stig , Vejlstrup Niels , Svendsen Jesper H. , Olesen Morten S.
Published: June 2020

Atrial fibrillation (AF) has traditionally been considered an electrical heart disease. However, genetic studies have revealed that the structural architecture of the heart also play a significant role. We evaluated the functional and structural consequences of harboring a titin-truncating variant (TTNtv) in AF patients, using cardiac magnetic resonance (CMR). Seventeen early-onset AF cases carrying a TTNtv, were matched 1:1 with non-AF controls and a replication cohort of early-onset AF cases without TTNtv, and underwent CMR. Cardiac volumes and left atrial late gadolinium enhancement (LA LGE), as a fibrosis proxy, were measured by a blinded operator. Results: AF cases with TTNtv had significantly reduced left ventricular ejection fraction (LVEF) compared with controls (57 ± 4 vs 64 ± 5%, P < 0.001). We obtained similar findings in early-onset AF patients without TTNtv compared with controls (61 ± 4 vs 64 ± 5%, P = 0.02). We furthermore found a statistically significant increase in LA LGE when comparing early-onset AF TTNtv cases with controls. Using state-of-the-art CMR, we found that early-onset AF patients, irrespective of TTNtv carrier status, had reduced LVEF, indicating that early-onset AF might not be as benign as previously thought.
The Impact of Trimetazidine on Disease Severity and Quality of Life in Parkinson’s Disease
Authors: Pintér Dávid , Juhász Annamária , Harmat Márk , Janszky József , Kovács Norbert
Published: June 2020

Trimetazidine is contraindicated in movement disorders, however, a not negligible part of trimetazidine users is still patients with Parkinson’s disease (PD). The present study aimed to objectively determine the impact of trimetazidine on the severity of symptoms and the health-related quality of life of patients with PD by measuring changes after its withdrawal. A consecutive series of 42 patients with PD using trimetazidine underwent detailed neurological and neuropsychological assessments at baseline and three months after the discontinuation of trimetazidine. Clinically relevant improvements were achieved with discontinuation of trimetazidine according to changes in scores of each part of the Movement Disorder Society-sponsored Unified Parkinson’s Disease Rating Scale (Part I: −25.7%, p < 0.001; Part II: −23.8%, p < 0.001; Part III: −28.5%, p < 0.001; Part IV: −30.1%, p = 0.004) and total scores of the Non-Motor Symptoms Scale (−25.6%, p = 0.004) and the Montgomery-Asberg-Depression Rating Scale (−20.1%, p = 0.001). Benefits resulting from the withdrawal of the drug also manifested in the improvement of the health-related quality of life based on changes in the summary index of the 39-item Parkinson’s Disease Questionnaire (−18.2%, p = 0.031). Our results provide clinical rationale for strictly avoiding the use of trimetazidine in PD. Discontinuation of trimetazidin results in clinically relevant improvements in Parkinsonian symptoms.
Evaluating the effect of overharvesting on genetic diversity and genetic population structure of the coconut crab
Authors: Yorisue Takefumi , Iguchi Akira , Yasuda Nina , Yoshioka Yuki , Sato Taku , Fujita Yoshihisa
Published: June 2020

Birgus latro(coconut crab) is an edible crustacean that has experienced serious overharvesting throughout its whole habitat range; however, the negative effects of overharvesting on the genetic diversity withinB. latropopulations have not been elucidated. Here, we report sex ratio, body size, and genetic diversity in populations ofB. latroin the Ryukyu Islands where large-male–biased overharvesting ofB. latrohas continued. In 2 of the study populations, the sex ratio was significantly skewed toward females, and in all of the study populations large males were rare, which we attributed to sex- and size-biased overharvesting. We found no differences in genetic diversity between small and large individuals, suggesting that genetic diversity, even among the large (i.e., old) individuals, may have had already been negatively affected by overharvesting. Continued monitoring of sex ratio, body size and genetic diversity are needed for effective management of the study populations.
A smart switching system to enable automatic tuning and detuning of metamaterial resonators in MRI scans
Authors: Saha Shimul , Pricci Roberto , Koutsoupidou Maria , Cano-Garcia Helena , Katana Ditjon , Rana Srinivas , Kosmas Panagiotis , Palikaras George , Webb Andrew , Kallos Efthymios
Published: June 2020

We present a radio-frequency-activated switching system that can automatically detune a metamaterial resonator to enhance magnetic resonance imaging (MRI) performance. Local sensitivity-enhancing metamaterials typically consist of resonant components, which means that the transmitted radio frequency field is spatially inhomogeneous. The switching system shows for the first time that a metamaterial resonator can be detuned during transmission and tuned during reception using a digital circuit. This allows a resonating system to maintain homogeneous transmit field while maintaining an increased receive sensitivity. As a result, sensitivity can be enhanced without changing the system-provided specific absorption rate (SAR) models. The developed digital circuit consists of inductors sensitive to the transmit radio-frequency pulses, along with diodes acting as switches to control the resonance frequency of the resonator. We first test the automatic resonator detuning on-the-bench, and subsequently evaluate it in a 1.5 T MRI scanner using tissue-mimicking phantoms. The scan results demonstrate that the switching mechanism automatically detunes the resonator in transmit mode, while retaining its sensitivity-enhancing properties (tuned to the Larmor frequency) in receive mode. Since it does not require any connection to the MRI console, the switching system can have broad applications and could be adapted for use with other types of MRI scanners and field-enhancing resonators.
The early predictive value of routine laboratory tests on the severity of acute pancreatitis patients in pregnancy: a retrospective study
Authors: Jin Di , Tan Jixue , Jiang Jingsun , Philips Dana , Liu Ling
Published: June 2020

Acute pancreatitis in pregnancy (APIP) varies in severity from a self-limiting mild condition to a severe life-threatening condition, and its severity is significantly correlated with higher risks of maternal and foetal death. This study evaluated the early predictive value of routine laboratory tests on the severity of APIP patients. We enrolled 100 patients with APIP in West China Hospital. Initial routine laboratory tests, including the biochemistry and hematologic tests were collected within 48 hours after the onset of APIP. For predicting SAP in AP, LDH had the highest specificity of 0.879. RDW was a suitable predictive marker as it had the sensitivity of 0.882. Lower levels of triglycerides (<4.72 mmol/L) predicted mild AP of APIP, with an area under the curve (AUC) of 0.724, and a negative predictive value of 0.80. Furthermore, a risk score was calculated based on white blood cells, neutrophils, RDW, LMR and LDH, as an independent marker (adjusted odds ratio = 3.013, 95% CI 1.893 to 4.797, P < 0.001), with the highest AUC of 0.906, a sensitivity of 0.875 and a specificity of 0.828. In conclusion, the risk score we recommended was the powerful marker to aid in the early prediction of the severity of APIP patients.
Risk-taking and fairness among cocaine-dependent patients in dual diagnoses: Schizophrenia and Anti-Social Personality Disorder
Authors: Sabater-Grande Gerardo , Haro Gonzalo , García-Gallego Aurora , Georgantzís Nikolaos , Herranz-Zarzoso Noemí , Baquero Abel
Published: June 2020

This study reports experimental results from a clinical sample of patients with a cocaine-related disorder and dual diagnosis: Schizophrenia and Anti-Social Personality Disorder. Both types of patients as well as a non-clinical group of students performed two incentivized decision-making tasks. In the first part of the experiment, they performed a lottery-choice task in order to elicit their degree of risk aversion. In the second part, they decided in two modified dictator games aimed at eliciting their aversion to advantageous and disadvantageous inequality. It is found that the Anti-Social Personality Disorder group exhibits no significant differences from the non-clinical sample in either task. However, compared with the students’ sample, subjects from the group with schizophrenia show more risk aversion and exhibit more aversion towards disadvantageous inequality.
Comparative Performance of Body Composition Parameters in Prediction of Death in Hospitalized Patients on Maintenance Hemodialysis: A Cohort Study
Authors: Wu Buyun , Yan Chenyan , Zhang Sufeng , Ge Yifei , Xu Xueqiang , Wang Yajie , Xu Lin , Zhang Chengning , Huang Zhimin , Ren Haibin , Wu Jingjing , Xing Changying , Mao Huijuan
Published: June 2020

We compared the prognostic value of nutritional or volumetric parameters measured by body composition in hospitalized patients on maintenance hemodialysis. We conducted a cohort study to assess the association of different parameters of body composition with all-cause mortality in inpatients admitted to our nephrology department from January 2014 to December 2016. Of the 704 study patients, 160 (22.7%) died during a median follow-up of 33 months. In multivariate adjusted Cox models, higher ratio of extracellular water to body cell mass (ECW/BCM) (adjusted HR per 1-SD, 1.49; 95% CI, 1.19 to 1.85), lower lean tissue index (LTI) (adjusted HR per 1-SD, 0.70; 95% CI, 0.57 to 0.86) and lower body cell mass index (BCMI) (adjusted HR per 1-SD, 0.70; 95% CI, 0.58 to 0.85) were associated with a significantly greater risk of death. When these parameters were added to the fully adjusted model, BCMI performed best in improving the predictability for all-cause mortality (integrated discrimination improvement = 0.02, P = 0.04; net reclassification index = 0.11, P = 0.04). Among body composition indexes, ECW/BCM was the most relevant fluid volume indices to mortality and BCMI and LTI were the most relevant nutritional status indices to mortality in maintenance hemodialysis patients.
Mapping CRISPR spaceromes reveals vast host-specific viromes of prokaryotes
Authors: Shmakov Sergey A. , Wolf Yuri I. , Savitskaya Ekaterina , Severinov Konstantin V. , Koonin Eugene V.
Published: June 2020

CRISPR arrays contain spacers, some of which are homologous to genome segments of viruses and other parasitic genetic elements and are employed as portion of guide RNAs to recognize and specifically inactivate the target genomes. However, the fraction of the spacers in sequenced CRISPR arrays that reliably match protospacer sequences in genomic databases is small, leaving the question of the origin(s) open for the great majority of the spacers. Here, we extend the spacer analysis by examining the distribution of partial matches (matching k-mers) between spacers and genomes of viruses infecting the given host as well as the host genomes themselves. The results indicate that most of the spacers originate from the host-specific viromes, whereas self-targeting is strongly selected against. However, we present evidence that the vast majority of the viruses comprising the viromes currently remain unknown although they are likely to be related to identified viruses.
6π-Electrocyclization in water: microwave-assisted synthesis of polyheterocyclic-fused quinoline-2-thiones
Authors: Li Xiao-Yun , Liu Yan , Chen Xiao-Lan , Lu Xin-Yuan , Liang Xing-Xing , Zhu Shan-Shan , Wei Chuan-Wan , Qu Ling-Bo , Yu Bing
Published: June 2020

Microwave-assisted synthesis of polyheterocyclic-fused quinoline-2-thiones through the annulation of ortho-heteroaryl anilines and CS2 was realized in water without using any catalysts and additives.
A fluorescent probe bearing two reactive groups discriminates between fluoride-containing G series and sulfur-containing V series nerve agents
Authors: Weihui Wu , Shaohui Sui , Jian Li , Liang Zong , Dan Li , Yanhua Xiao , Lianyuan Wang , Haiyan Zhu , Yonglin Shen , Zhigang Jiang
Published: June 2020

A fluorescent probe bearing two functional groups was designed to discriminate fluoride-containing G and sulfur-containing V series nerve agents through reacting with fluorides and thiols, which exhibited obvious and diverse fluorescence changes.
Material composition and peptide sequence affects biomolecule affinity to and selectivity for h-boron nitride and graphene
Authors: Brljak Nermina , Parab Atul D. , Rao Rahul , Slocik Joseph M. , Naik Rajesh R. , Knecht Marc R. , Walsh Tiffany R.
Published: June 2020

Pathways to nanosheet selective binding peptides are presented.
Insertion of Ni(0) and Pd(0) precursors into the Si–Si bond of a disilane with two hypercoordinate silicon atoms
Authors: Usui Ryosuke , Sunada Yusuke
Published: June 2020

The activation of the silicon–silicon bond in disilane Ph2Si(μ-PzMe2)2SiPh2 (1), which possesses two five-coordinate silicon centers, was achieved by a reaction with Pd(CNtBu)2 or in situ generated Ni(0)–NHC precursors of modest steric demand.
Synthesis of di(hetero)aryl sulfides by defluorinative sulfenylation of polyfluoroalkyl ketones with sodium sulfinates or arylsulfonyl chlorides
Authors: Chu Xue-Qiang , Xie Ting , Wang Ya-Wen , Li Xiang-Rui , Rao Weidong , Xu Haiyan , Shen Zhi-Liang
Published: June 2020

Cascade reactions of α-perfluoroalkyl ketones with sodium sulfinates or arylsulfonyl chlorides that allowed the efficient synthesis of fluoroalkylated di(hetero)aryl sulfide derivatives under transition metal-free conditions were developed.
Selective enclathration of xylenols: synergistic effects of mixed hosts
Authors: Bouanga Boudiombo Jacky S. , Su Hong , Ravenscroft Neil , Bourne Susan A. , Nassimbeni Luigi R.
Published: June 2020

The six xylenol (XYL) isomers can be separated by selective enclathration with the host 4,4-isopropylidene bisphenol, H1. This selectivity is enhanced by the use of a second, complementary host in combination with H1.
Fast, tunable and reversible anion-exchange in CsPbBr3 perovskite nanocrystals with hydrohalic acids
Authors: Dutt V. G. Vasavi , Akhil Syed , Mishra Nimai
Published: June 2020

Anion-exchange with metal chloride salts in CsPbBr3 perovskite nanocrystals.
Dynamic structural changes of supported Pd, PdSn, and PdIn nanoparticles during continuous flow high pressure direct H2O2synthesis
Authors: Doronkin Dmitry E. , Wang Sheng , Sharapa Dmitry I. , Deschner Benedikt J. , Sheppard Thomas L. , Zimina Anna , Studt Felix , Dittmeyer Roland , Behrens Silke , Grunwaldt Jan-Dierk
Published: June 2020

The structure of mono- and bimetallic supported Pd, PdSn, and PdIn NPs was monitored with a combination of techniques during continuous H2O2synthesis with H2O2production rates up to 580 mmolH2O2gcat−1h−1.
Silver nanoparticles stabilized by a metal–organic framework (MIL-101(Cr)) as an efficient catalyst for imine production from the dehydrogenative coupling of alcohols and amines
Authors: Gumus Ilkay , Karataş Yaşar , Gülcan Mehmet
Published: June 2020

In this paper, we present silver nanoparticles supported on a metal–organic framework (Ag@MIL-101) as a catalyst for the one-pot tandem synthesis of imines from alcohols and amines.
Cobalt-based heterogeneous catalysts in an electrolyzer system for sustainable energy storage
Authors: Maiti Anurupa
Published: June 2020

Nowadays, the production of hydrogen and oxygen focuses on renewable energy techniques and sustainable energy storage.
Highly efficient light-driven methane coupling under ambient conditions based on an integrated design of a photocatalytic system
Authors: Lang Junyu , Ma Yuli , Wu Xuechen , Jiang Yueyue , Hu Yun Hang
Published: June 2020

A novel photocatalytic system for highly efficient non-oxidative coupling of methane was demonstrated by dispersing a metal loaded TiO2 catalyst on the light-diffuse-reflection surface with a continuous flow reactor.
Quantitative analysis of yeast MAPK signaling networks and crosstalk using a microfluidic device
Authors: Lee Byungjin , Jeong Seong-Geun , Jin Si Hyung , Mishra Ranjan , Peter Matthias , Lee Chang-Soo , Lee Sung Sik
Published: June 2020

Eukaryotic cells developed complex signaling networks to sense their environment and respond to various stress conditions. We investigate yeast MAPK signaling pathways and their crosstalk by a microfluidic device coupled to quantitative microscopy.
Stimuli-responsive supramolecular polymer network based on bi-pillar[5]arene for efficient adsorption of multiple organic dye contaminants
Authors: Wei Tai-Bao , Qi Li-Hua , Zhang Qin-Peng , Zhang Wen-Huan , Yao Hong , Zhang You-Ming , Lin Qi
Published: June 2020

A novel supramolecular polymer network gel has been successfully prepared via bi-pillar[5]arene and a tripodal guest, exhibiting multi-stimuli-responsiveness and efficient adsorption of organic dyes.
Relieving immunosuppression during long-term anti-angiogenesis therapy using photodynamic therapy and oxygen delivery
Authors: He Qianyuan , Zhang Zhanjie , Liu Haojie , Tuo Zhan , Zhou Jie , Hu Yan , Sun Yajie , Wan Chao , Xu Zushun , Lovell Jonathan F. , Hu Desheng , Yang Kunyu , Jin Honglin
Published: June 2020

Angiogenesis is an irreplaceable therapeutic cancer target, where anti-angiogenesis are drugs that are limited by their hydrophobicity and low therapeutic effects.
Emergent magnetic texture in driven twisted bilayer graphene
Authors: Bahamon Dario A. , Gómez-Santos G. , Stauber T.
Published: June 2020

A superlattice of magnetic moments appears for low twist angles in twisted bilayer graphene under asymmetric driving.
NIR-controlled HSP90 inhibitor release from hollow mesoporous nanocarbon for synergistic tumor photothermal therapy guided by photoacoustic imaging
Authors: Sun Jiaxin , Li Yongjing , Teng Yilong , Wang Sheng , Guo Jia , Wang Changchun
Published: June 2020

Hollow mesoporous carbon nanospheres were used as drug carriers for mild-temperature photothermal therapy, which showed a significant NIR-enhanced synergistic tumor therapeutic effect guided by photoacoustic imaging.
Facile preparation of one-dimensional nanostructures through polymerization-induced self-assembly mediated by host–guest interaction
Authors: Shen Liangliang , Li Yahui , Lu Qunzan , Qi Xiaoliang , Wu Xuan , Shen Jianliang
Published: June 2020

A RAFT aqueous dispersion polymerization of ferrocenylmethyl acrylate mediated by host–guest interaction was investigated and a series of peculiar one-dimensional morphologies can be readily obtained.
Influence of the cathode microstructure on the stability of inverted planar perovskite solar cells
Authors: Sirotinskaya Svetlana , Schmechel Roland , Benson Niels
Published: June 2020

The microstructure of the metal contact has a significant influence on the PSC aging properties. In this contribution we show that perovskite decomposition and iodide diffusion can be suppressed by using nanocrystalline Ni metallization.
Automated glycan assembly of Streptococcus pneumoniae type 14 capsular polysaccharide fragments
Authors: Louçano João , Both Peter , Marchesi Andrea , Bino Linda del , Adamo Roberto , Flitsch Sabine , Salwiczek Mario
Published: June 2020

A streamlined automated synthesis for S. pneumoniae type 14 and Group B Streptococcus type III capsular oligosaccharides with only one set of three building blocks is presented. Competitive ELISA provides some insight into minimal epitope.
High-performance near-infrared Schottky-photodetector based graphene/In2S3 van der Waals heterostructures
Authors: Chen Long , Li Zhenghan , Yan Chaoyi
Published: June 2020

The photodetectors based on graphene/In2S3 van der Waals heterostructures through junction carrier separation exhibited an excellent infrared performance of high photoresponsivity of 0.49 mA W−1, external quantum efficiency of 0.07%, and detectivity of 3.05 × 107 jones using an 808 nm laser.
Removal of the A10 adenosine in a DNA-stabilized Ag16 nanocluster
Authors: Cerretani Cecilia , Kondo Jiro , Vosch Tom
Published: June 2020

We investigated the effect of removing the A10 from 5′-CACCTAGCGA-3′ on the photophysical and structural properties of a DNA-stabilized Ag16NC.
Surface coating determines the inflammatory potential of magnetite nanoparticles in murine renal podocytes and mesangial cells
Authors: Selc Michal , Razga Filip , Nemethova Veronika , Mazancova Petra , Ursinyova Monika , Novotova Marta , Kopecka Kristina , Gabelova Alena , Babelova Andrea
Published: June 2020

Primary renal podocytes are more susceptible to MNPs exposure than primary renal mesangial cells.
A novel critical control point and chemical marker identification method for the multi-step process control of herbal medicines via NMR spectroscopy and chemometrics
Authors: Zhao Fang , Li Wenzhu , Pan Jianyang , Chen Zeqi , Qu Haibin
Published: June 2020

NMR and chemometric-based critical control point and chemical marker identification for the multi-step process control of herbal medicines.
Palladium nanoparticles on a pyridinium supported ionic liquid phase: a recyclable and low-leaching palladium catalyst for aminocarbonylation reactions
Authors: Adamcsik Bernadett , Nagy Enikő , Urbán Béla , Szabó Péter , Pekker Péter , Skoda-Földes Rita
Published: June 2020

SILP catalyst with grafted pyridinium ions was used for either mono- or double carbonylation depending on the reaction conditions. Good recyclability and low palladium loss were observed during the synthesis of pharmaceutically active compounds.
Graphene quantum dot based materials for sensing, bio-imaging and energy storage applications: a review
Authors: Kumar Y. Ravi , Deshmukh Kalim , Sadasivuni Kishor Kumar , Pasha S. K. Khadheer
Published: June 2020

Graphene quantum dots (GQDs) are an attractive nanomaterial consisting of a monolayer or a few layers of graphene having excellent and unique properties.
Multi-omics characterization of the osmotic stress resistance and protease activities of the halophilic bacterium Pseudoalteromonas phenolica in response to salt stress
Authors: Song Won-Suk , Kim Seong-Min , Jo Sung-Hyun , Lee Jae-Seung , Jeon Hyo-Jin , Ko Byoung Joon , Choi Kwon-Young , Yang Yung-Hun , Kim Yun-Gon
Published: June 2020

Multi-omics study showed the osmoprotective mechanism and changes of proteolytic activities of Pseudoalteromonas phenolica in response to salt stress.
Efficient and stereoselective one-pot synthesis of benzo[b]oxazolo[3,4-d][1,4]oxazin-1-ones
Authors: Zhao Hongyi , Zhao Wenting , Cheng Shihao , Lu Haijia , Zhang Dongfeng , Huang Haihong
Published: June 2020

An efficient and mild one-pot convergent synthesis protocol has been developed for benzo[b]oxazolo[3,4-d][1,4]oxazin-1-one derivatives through the Mitsunobu reaction and sequential cyclization.
Revision of the structure of isochaetoglobosin Db based on NMR analysis and biosynthetic consideration
Authors: Wang Yan-duo , Li Yuan-yuan , Tan Xiang-mei , Chen Lin , Wei Zhong-qi , Shen Li , Ding Gang
Published: June 2020

Isochaetoglobosin Db is a new chaetoglobosin possessing a unique 3,4-substituted pyrrole ring isolated and named by Qiu et al., and it is different from any one of the 14 sub-types in the macrocyclic ring of chaetoglobosins classified in our previous work.
Plasticity control of poly(vinyl alcohol)–graphene oxide nanocomposites
Authors: Panova Tatiana V. , Efimova Anna A. , Berkovich Anna K. , Efimov Aleksander V.
Published: June 2020

The plasticity of poly(vinyl alcohol)–graphene oxide nanocomposites was significantly improved and the failure mechanism changed from brittle to ductile failure.
Digital light processing 3D printing of modified liquid isoprene rubber using thiol-click chemistry
Authors: Strohmeier Lara , Frommwald Heike , Schlögl Sandra
Published: June 2020

Elastomer-based 3D objects with good resolution are fabricated by additive manufacturing of photo-reactive liquid rubber formulations with digital light processing.
Microwave catalyzed carbothermic reduction of zinc oxide and zinc ferrite: effect of microwave energy on the reaction activation energy
Authors: Omran Mamdouh , Fabritius Timo , Heikkinen Eetu-Pekka , Vuolio Tero , Yu Yaowei , Chen Guo , Kacar Yilmaz
Published: June 2020

Catalytic effect of microwave energy on carbothermic reduction of zinc ferrite.
A photovoltaic-driven solid-state Zn–CO2 electrochemical cell system with sunlight-insusceptible chemical production
Authors: Wang Xueyuan , Ghausi Muhammad Arsalan , Yang Rui , Wu Maoxiang , Xie Jiafang , Wang Yaobing
Published: June 2020

A photovoltaic-driven solid-state Zn–CO2 electrochemical cell system continuously converts CO2, overcoming the real-time sunlight-dependence of natural leaves and current artificial leaves.
High performance multicomponent bifunctional catalysts for overall water splitting
Authors: Bose Ranjith , Jothi Vasanth Rajendiran , Karuppasamy K. , Alfantazi Akram , Yi Sung Chul
Published: June 2020

Designing highly active bifunctional electrocatalysts from Earth-abundant elements has great prospects for substituting precious-metal based catalysts in energy conversion processes, such as water splitting.
Understanding the role of Sn substitution and Pb-□ in enhancing the optical properties and solar cell efficiency of CH(NH2)2Pb1−x−ySnx□yBr3
Authors: Jain Manjari , Singh Arunima , Basera Pooja , Kumar Manish , Bhattacharya Saswata
Published: June 2020

We study the role of Sn substitution and Pb vacancies in reducing the lead concentration and enhancing the stability and solar cell efficiency of promising formamidinium lead bromide perovskites.
Enhancing the properties of perovskite quantum dot light emitting devices through grid structures formed by trioctylphosphine oxide
Authors: Zhu Hanwen , Tian Yu , Yang Supeng , Shen Yang , Xu Enze , Tang Jianxin , Jiang Yang
Published: June 2020

Randomly distributed concave–convex structures formed by TOPO solution contribute to the performance of CsPbBr3 QLEDs.
Biochemical Society 2021 award winners
Authors: Crabb Katie
Published: June 2020

Ten bioscientists have been honoured in the annual Biochemical Society Awards. Each winner exemplifies the very best of the molecular biosciences community in fields ranging from DNA repair and the motile behaviour of microorganisms to muscle metabolism and complex membrane trafficking.
Gesture recognition for transhumeral prosthesis control using EMG and NIR
Authors: Nsugbe Ejay , Phillips Carol , Fraser Mike , McIntosh Jess
Published: June 2020

A key challenge associated with myoelectric prosthesis limbs is the acquisition of a good quality gesture intent signal from the residual anatomy of an amputee. In this study, the authors aim to overcome this limitation by observing the classification accuracy of the fusion of wearable electromyography (EMG) and near‐infrared (NIR) to classify eight hand gesture motions across 12 able‐bodied participants. As part of the study, they investigate the classification accuracy across a multi‐layer perceptron neural network, linear discriminant analysis and quadratic discriminant analysis for different sensing configurations, i.e. EMG‐only, NIR‐only and EMG‐NIR. A separate offline ultrasound scan was conducted as part of the study and served as a ground truth and contrastive basis for the results picked up from the wearable sensors, and allowed for a closer study of the anatomy along the humerus during gesture motion. Results and findings from the work suggest that it could be possible to further develop transhumeral prosthesis using affordable, ergonomic and wearable EMG and NIR sensing, without the need for invasive neuromuscular sensors or further hardware complexity.
Reduced inverters fed BDCM drives: an attempt to improve cost‐effectiveness, compactness and reliability in hybrid vehicles
Authors: Ben Rhouma Asma
Published: June 2020

Following the climatic changes, there is a universal commitment to reduce greenhouse gas emissions, especially those due to mobility. A particular interest is addressed to hybrid propulsion systems, which are currently considered as viable candidates for a sustainable mobility. Within this commitment, the study proposes an approach to improve the cost‐effectiveness, compactness and reliability of the electric drive unit of hybrid propulsion systems. This is achieved thanks to different associations of brushless DC motors (BDCMs) and reduced topologies of DC/AC converters such as the four switch inverter and three switch inverter. A special attention is focused upon the analysis of the sequences and commutations characterising the six‐phase and three‐phase BDCM drive operation. Implementation schemes of dedicated control strategies are given. Moreover, a comparison of selected features related to the ratings of the investigated BDCM drives is carried out and commented. Experimental results are provided to validate the performances of a reduced structure inverter fed three‐phase BDCM under the dedicated control strategy.
Exploiting periodic orbits as dynamical clues for Kepler and K2 systems
Authors: Antoniadou Kyriaki I. , Libert Anne-Sophie
Published: June 2020

Aims. Many extrasolar systems possessing planets in mean-motion resonance or resonant chain have been discovered to date. The transit method coupled with transit timing variation analysis provides an insight into the physical and orbital parameters of the systems, but suffers from observational limitations. When a (near-)resonant planetary system resides in the dynamical neighbourhood of a stable periodic orbit, its long-term stability, and thus survival, can be guaranteed. We use the intrinsic property of the periodic orbits, namely their linear horizontal and vertical stability, to validate or further constrain the orbital elements of detected two-planet systems.

Methods. We computed the families of periodic orbits in the general three-body problem for several two-planet Kepler and K2 systems. The dynamical neighbourhood of the systems is unveiled with maps of dynamical stability.

Results. Additional validations or constraints on the orbital elements of K2-21, K2-24, Kepler-9, and (non-coplanar) Kepler-108 near-resonant systems were achieved. While a mean-motion resonance locking protects the long-term evolution of the systems K2-21 and K2-24, such a resonant evolution is not possible for the Kepler-9 system, whose stability is maintained through an apsidal anti-alignment. For the Kepler-108 system, we find that the stability of its mutually inclined planets could be justified either solely by a mean-motion resonance, or in tandem with an inclination-type resonance. Going forward, dynamical analyses based on periodic orbits could yield better constrained orbital elements of near-resonant extrasolar systems when performed in parallel to the fitting of the observational data.
Revisiting the study of the life cycles of predatory ground beetles (Coleoptera, Carabidae) in the agrolandscape of the foothill zone of Krasnodar Krai
Authors: Khomitskiy Eugeniy , Zamotajlov Alexandr , Beliy Alexandr , Esipenko Leonid , Balakhnina Irina
Published: June 2020

The article discusses the results of 4-year studies of the demographic structure and life cycles of predatory ground beetles populations in the agrolandscape and adjacent biocenoses of the foothill zone of Krasnodar Krai. The main “residential” and “transit” biotopes of 102 species were identified. It was found that among the studied species 36 ones have a full age structure; currently, life cycles for 4 widespread species in this zone have been completely reconstructed.
Prevalence rates of microsporidia in locusts and grasshoppers in South-Western Russia
Authors: Gerus Aleksei , Ignatieva Anastasia , Tokarev Уuri
Published: June 2020

Locusts and grasshoppers are dangerous polyphagous pests of agricultural crops. In the present paper, results of screening of Acridoidea populations in the South-Western Russia for microsporidia infections including locusts Locusta migratoria, Dociostaurus maroccanus, and Calliptamus italicus and grasshoppers Chorthippus loratus, Oedipoda caerulescens, and Acrida bicolor, are presented. Microsporidia prevalence rates were estimated using light microscopy of fresh smears. Out of 179 specimens of L. migratoria sampled between 2002 and 2019 in Krasnodar Territory, Astrakhan and Rostov Regions, none was infected with microsporidia. Similarly, 95 specimens of D. marrocanus from Krasnodar Territory (2017) and Dagestan Republic (2009) were also negative for microsporidia. Meanwhile, one positive case was detected for C. italicus corresponding to 0.5 % for the total amount of 192 exemplars collected from 2002 to 2019 in Krasnodar Territory, Astrakhan and Rostov Regions. As for grasshoppers, all Ch. loratus samplings in Krasnodar Territory in 2017-2019 were infected at the prevalence rates of 2.2-15 %, though no infection was found in 40 specimens in Crimea in 2019. In 56 individuals of O. caerulescens collected from Rostov Region and Krasnodar Territory, the microsporidia prevalence rate was 1.8 %. Among 96 specimens of A. bicolor, none was infected. In total, the microsporidia prevalence rates were higher in grasshoppers as compared to locusts, the difference being statistically significant at p<0.01.
Loci that determine long-term resistance to blast of Russian rice varieties
Authors: Goncharova Julia , Bragin Olesya , Goncharov Sergey , Kharitonov Evgeny
Published: June 2020

In all rice-growing countries, including Russia, among the economically important, dangerous and harmful diseases of rice, the main role is played blast (pathogen Pyricularia oryzae Cavara). The problem of resistance of rice plants to disease is one of the main problems in modern breeding in most countries. The most effective way to protect rice from blast is using resistant varieties created with marker assistant selection (MAS). The article presents data on chromosomal regions that provide long-term resistance of varieties to pathogen in Russia. The groups of stable and unstable samples significantly differed in the presence of polymorphic loci on the fifth, sixth, eighth, ninth and second chromosomes, which reduces the complexity of evaluating selection material due to the primary screening of gene plasms by variability of resistance loci in the identified chromosomal regions.
The study of the antifungal activity of the Bacillus subtilis BZR 336g strain under the conditions of periodic cultivation with the addition of citric acid, corn extract and some microelements
Authors: Asaturova Anzhela , Gyrnets Evgeny , Allakhverdian Valeria , Astakhov Mikhail , Saenko Ksenia
Published: June 2020

We studied the antifungal activity of the Bacillus subtilis BZR 336g strain against the test culture of the fungus Fusarium oxysporum var. orthoceras App. et Wr. BZR 6, depending on the addition of citric acid crystalline hydrate, a microelements solution and corn extract to the liquid nutrient medium. It was found that citric acid at a concentration of 15 g/l improves the bioavailability of microelements and increases antifungal activity. Corn extract and microelements without the formation of a chelate form with citric acid do not affect the fungicidal properties of B. subtilis BZR 336g. However, the corn extract at a concentration of 3 g / l increases the titer of bacteria in the liquid culture from 2 ± 0.1 × 108 to 1 ± 0.08 × 108 CFU/ml. The combined use of the studied components allowed us to achieve a significant increase in the antifungal activity of B. subtilis BZR 336g by 3.1 times. At the same time, the effect of synergism in their complex interaction was noted, which is probably due to a qualitative and quantitative change in the composition of B. subtilis BZR 336g antifungal metabolites.
Pathogenic post-effect of entomopathogenic fungi on phytophagous pests and entomophagous biocontrol agents
Authors: Pavlyushin Vladimir
Published: June 2020

Phytosanitary optimization of agricultural ecosystems under conditions of glasshouses and organic farming urgently demands guaranteed effect of plant protection. This can be achieved only through effective exploitation of a complex of biological agents, including arthropod predators and parasites, entomopathogenic fungi, nematodes and other microbes. Entomopathogenic fungi Beauveria bassiana and Lecanicillium muscarium are characterized by facultative parasitism and possess high potential to control phytophagous insects, including pests of vegetable crops in glasshouses. In aphids, fungal pathogenesis was found to be comprised of primary mycosis and toxigenic post-effect in a row of consequent generations. For example, L. muscarium and B. bassiana had an adverse effect on fertility and survival rates of females of aphids Aphis gossypii up to the fifth generation. The longevity, reproductive period and amount of progeny were decreased in aphids treated with water suspension of fungal conidia. It can be deduced that the post-effect is caused by toxic action of metabolites as no evident mycosis was observed in the experiments. Similar type of after-effect is observed in the lacewing Chrysopa carnea contaminated with fungal conidia. The effect is also toxigenic being most prominent in the first generation of the survivors’ progeny and traceable up to the fifth generation. The consequences of the infection are best seen in the rate adult emergence which is twice as low as compared to control. This knowledge is essential to avoid antagonism between different groups of natural enemies exploited in biological control and to design adequate technology for their application.
Entomopathogenic microorganisms in locusts and grasshoppers populations and prospects for their use for control of this pest group
Authors: Lednev Georgiy , Levchenko Maxim , Kazartsev Igor
Published: June 2020

Brief information on the main groups of microorganisms parasitizing on locusts and grasshoppers is given. It has been shown that viral and most bacterial infections have no practical prospects, both as natural regulators of density populations and as potential producers of bioinsecticides. Alpha-proteobacteria, entomophthoralean fungi and microsporidia may make some contributions as natural mechanisms of population dynamics. The most significant group as producers of biopesticides are anamorphic ascomycetes from the genera Metarhizium and Beauveria.
Technological Effectiveness of Chelated Micronutrient Fertilizers in Leaf Treatments Inducing Grapes Resistance to Biotic and Abiotic Stresses
Authors: Yurchenko Eugeniya , Artamonov Alexander
Published: June 2020

Fertilizers based on complexes of chelated trace elements are the most common and effective agricultural products for the induction of protective-compensatory and other adaptive reactions of plants. The influence of various leaf treatments technologies with chelated micronutrient fertilizers application on the stability of grapes is studied under increasing abiotic and biotic environment factors within the Taman Peninsula (Russia) considering the content of proline, photosynthetic pigments (chlorophylls and carotenoids), total water in the leaves, as well as the development of infectious drying of clusters and leaf spotting reduction due to the treatment. The new optimized scheme application on the chelated micronutrient fertilizers showed a predominantly positive effect on the grape plants adaptation to high-temperature drought and fungal diseases susceptibility, as well as essential increase of the average cluster weight and yield per hectare.
Application of biological agents to protect cucumber plants against multiple pests in greenhouses in Northwest Russia
Authors: Kozlova Ekaterina , Krasavina Lidiya
Published: June 2020

Dynamics of the main pests of cucumber over a five-year period were analysed. The impact of meteorological conditions on the pest dynamics was observed when growing photo culture cucumbers in a greenhouse all year round. The possibility of successful and efficient use of cotton aphid, spider mite, tobacco thrips, greenhouse whitefly and noctuid moth entomophagous was demonstrated. Application rates for several entomophagous were proposed for prevention and protection of cucumber plants against the above-mentioned pests.
Ecological evaluation of technologies for application of plant protection measures by spraying method
Authors: Lysov Anatolij , Kornilov Timur
Published: June 2020

The biological and economic effectiveness of plant protection measures depends not only on the correct choice of pesticide, but also on the quality of its application to the processed target objects. The article discusses the results of assessing the quality of applying herbicides by spraying using low-volume spraying technology, ULV spraying without forced and forced precipitation of small droplets, and treatment with cold aerosol. To assess the impact of the quality of the application of plant protection products on the environmental safety of the use of herbicides, two main indicators were used: – uniform distribution of the working fluid over the treated area: – the amount of drift of small drops from the treatment area. The analysis of methodological approaches and regulatory documents for assessing the potential risk of pesticides for the environment in European countries and in Russia is given.Based on the obtained experimental data on the coefficients of variation in the distribution of the drug over the effective coverage width, an expert assessment of the drug overuse was carried out using various technologies. An expert assessment of the drift of small drops of the working fluid from the treatment zone was also carried out. A comparative assessment of technologies was carried out according to the indicated environmental safety indicators for the use of the herbicide Gezagard WP on potato plantings.
Y chromosome effect on prenatal live weight growth of laboratory minipigs
Authors: Shatokhin Kirill , Nikitin Sergey , Knyazev Sergey , Zaporozhets Vera , Pashkovskiy Sergey
Published: June 2020

This paper describes the results of the influence of Y-chromosome gene complex on pre- and postnatal growth of piglets of laboratory mini-pigs ICG SB RAS. Breeding group includes four genealogical lines of boars united by a successive father-son relationship. Three lines: MS2853, MS2987, and VTN300 inherited their Y chromosomes from boars of Vietnamese-South Asian breed. The fourth line (LNDR07) received Y chromosome from the Landrace boar. This study revealed that all three lines of boars carrying Asian Y chromosome did not differ in weight of newborn offspring, while the weight and, correspondingly, prenatal growth of newborns of boars carrying European Y chromosome were statistically significantly less. Thus, at this stage of research, there is reason to believe that the selection group of mini-pigs ICG SB RAS contains polymorphism in the complex of Y-chromosome genes involved in the control of prenatal growth process. An assumption was considered that growth retardation during prenatal and early postnatal periods, as well as an increased proportion of culled offspring of boars carrying European Y chromosome can be caused by poor compatibility of its gene complex with the allele pool inherited from the mini pigs ICG SB RAS from Vietnamese breed.
Changes in live weight and biochemical blood indicators in Tyvan short-fat tailed sheep breed depending on the breeding zone and season of the year
Authors: Shimit Larisa , Biltuev Semyon , Achituev Vladimir , Zhamyanov Bair , Mongush Zhanna
Published: June 2020

The considers the research results of productive qualities and biological features of Tyvan short-fat tailed sheep breed depending on the season of the year and the breeding zone of the Republic of Tyva: mountain taiga-steppe, desert-steppe and dry steppe. The highest live weight was observed in sheep raised in the dry steppe zone. When studying the biochemical composition of the blood of sheep in the summer-autumn grazing period, the content in the blood of sheep of the compared groups of basic biochemical parameters is within the physiological norms. In the winter-spring period, when grazing sheep on rags of last year’s grass due to a deficiency in their diets of basic nutrients, the blood levels of animals of all groups of total protein, calcium and reserve alkalinity are below physiological norms.