bluuebunny/crossref_metadata_2025 huggingface dataset:
Ethics Of The Tutor In The Development Of Reflective Capabilities In Law Students
Authors: García Arias Nemis , Quevedo Arnaiz Ned
Published: January 2025

Tutor ethics refers to the ethical principles and standards that govern behavior and decisions in their specific field. These principles and standards are established to ensure that the tutor acts with integrity, honesty and responsibility when providing services to his students and the community. This research analyzed the student's assessment of aspects related to the ethics of the tutor in his comprehensive training for the profession and his warning regarding the influences exerted on the formation of reflective capacities during student research. The research was carried out using a mixed, qualitative and quantitative approach, for the analysis and interpretation of the student's evaluation in relation to the ethical function of the tutor. It was based on a non-experimental transactional design that covered the period from May to September 2023 with students in the eighth year of the Law Degree at UNIANDES Santo Domingo. The documentary analysis, direct observation, and survey techniques were used. It was possible to specify the characteristics of the tutor that points out to the students as important in the teacher's performance, where the responsibility, reflection and organization that the teachers have and what contribute to comprehensively training the students stand out. The role that the tutor plays in the formation of both reflection and professional ethics has been demonstrated in the opinions expressed by the students in this research
Innovation And Transformation Plan For Gastronomic Production Line In Pelileo Canton, Ecuador
Authors: Franco Pérez Aníbal Fernando , Tello Velastegui Adriano Israel
Published: January 2025

This study addresses the innovation and transformation of the gastronomic production line in the canton of San Pedro de Pelileo, province of Tungurahua, Ecuador, where gastronomic service providers face challenges related to food hygiene, culinary techniques, and customer service. The objective was to strengthen their skills through an intervention plan that includes training in innovative practices and the use of local products. The methodology consisted of the implementation of 10 theoretical-practical workshops held between May and September 2023, with the participation of 30 local actors from the gastronomic sector. Surveys were administered before and after the workshops to measure the impact on the knowledge acquired, as well as a satisfaction survey to assess the quality of the program. The results show a significant increase in the application of Good Manufacturing Practices and innovative techniques for food transformation, reaching 100% knowledge in these areas by the end of the plan. Additionally, participants expressed high satisfaction with the training received. In conclusion, the research demonstrates that the implementation of training programs focused on innovation and the use of local resources contributes to the economic and social development of gastronomic service providers, strengthening the sector’s competitiveness and promoting the sustainability of local enterprises
Teacher Evaluation In Postgraduate Studies: Reflections And Current Projections
Authors: Lalama Flores Marcos Aníbal , Castro Sánchez Fernando de Jesús , Lalama Gavilánez Marcos Stefano , Robalino Cáceres Estefanía Carmen
Published: January 2025

The teaching and learning process in postgraduate programs requires that instructors respond to multiple social and individual demands, which lead to the necessity of having up-to-date knowledge in their field of expertise, in teaching methodologies, in technological aspects, in teacher-student relationships, and in different learning approaches, among others. This ensures that postgraduate students maintain an active performance. Therefore, this study aims to present the results of an evaluation of the performance of postgraduate instructors. To this end, qualitative and quantitative methods are used, drawing from various sources of information such as student evaluations of instructors, self-assessments, evaluations by the academic coordinator, and the Postgraduate Directorate. In this context, the applied tool allows for the determination of the weighting of instructor performance in qualitative and quantitative terms, based on the "Generic Model for Evaluating the Learning Environment of Postgraduate Programs." Key points highlighted in the conclusions include the high quality of instructors in their respective fields of expertise, which is notably different from the negative perceptions students have regarding the academic aspects of the faculty. It is concluded that analyzing spaces for reflection within postgraduate classrooms is predominantly related to instructors, and these reflective spaces allow for optimization with high levels of academic rigor in the teaching and learning processes
Violation Of The Labor Rights Of Persons With Disabilities: Challenges And Perspectives
Authors: Limaico Mina Josué Ramón , Terán Vaca Claudio Antonio , Núñez Sanabria Juan Evangelista , Villa Zura Marco Patricio
Published: January 2025

This article analyzes the right to work of people with disabilities in Ecuador, guaranteed by the Constitution, which promotes equal conditions for all. However, the reality shows a significant exclusion of these people in both the public and private sectors, which limits their access to jobs appropriate to their abilities. Despite being a priority group, many people with disabilities, whether physical, mental or intellectual, face barriers that prevent them from obtaining stable jobs and fully enjoying legal benefits. The research uses qualitative and quantitative methods to highlight these inequalities and propose solutions to ensure their effective inclusion in the labor market
Patterns And Challenges Of Mobility Of Venezuelan Migrants In The City Of Tulcán, Ecuador
Authors: Cárdenas Revelo María José , Méndez Cabrita Carmen Marina , Chuga Quemac Rosa Evelyn
Published: January 2025

This research addresses the violations of constitutional and international human rights norms, focusing on the serious affectations to the rights of migrants. In particular, it analyzes article 137, numeral 11, fourth section of the Organic Law of Human Mobility, with emphasis on its legal and constitutional impact. Through an exhaustive bibliographic review, the problem of Venezuelan citizens transiting through Tulcán and its borders was studied. Articles from indexed journals and provisions of the law, which regulates human mobility but in some cases penalizes migration, were examined
Death With Dignity In Persons With Terminal Illnesses, Compared To Comparative Law
Authors: Torres Torres Leonso Dagoberto , Checa Andino Zuliana Esmeralda , Torres Apolo Kelly Solange
Published: January 2025

In recent years, the concept of dignified death has generated a constant debate from medical, social, ethical, religious and legal perspectives. This study analyzes, from comparative law, the dignified death of terminally ill persons. The research used a mixed approach: qualitative, through reflective quotes, and quantitative, with the use of statistical data. Theoretical and empirical methods were used, as well as documentary techniques and interviews to support the results. It was concluded that, in Ecuador, the laws recognize the patient's right to decide about his or her life and health, which requires decriminalizing the Penal Code to allow a digni-fied death without suffering
Analysis Of The Fermentation Processes Of Arabica Coffee And Its Impact On The Cup
Authors: Freire Muñoz Diego Armando , Franco Pérez Aníbal Fernando , Tello Velastegui Adriano Israel , Llundo Michelena Bolívar Javier
Published: January 2025

Arabica coffee is one of the most appreciated varieties worldwide, and the fermentation processes used in its production play a key role in the development of its flavor and aroma profiles. The objective of this study was to analyze the fermentation processes of Arabica coffee and their impact on the final quality in the cup. A mixed-method approach was adopted, combining qualitative and quantitative methodologies, evaluating critical variables such as temperature, pH, Brix degrees, and electrical conductivity across different processing methods (natural, honey, and washed). The results show that each processing method significantly affects the sensory attributes of the coffee: natural processes stand out for their fruity flavors, washed processes for their cleanliness and brightness, and honey processes for their sweetness. It is concluded that fermentation, when properly controlled, allows for the production of high-quality coffees, improving their scores in competitions and their market value; however, poorly managed fermentation can lead to defects that decrease both the quality and the price of the final product
Impact On The Rights To Good Living And Nature Due To Illegal Mining In The Parish Of Buenos Aires, Province Of Imbabura
Authors: Cruz Arboleda José Ignacio , Villa Zura Marco Patricio , Benavides Salazar Mishelle Estefanía , Isea Arguelles Josía Jeseff
Published: January 2025

The main purpose of this research was to analyze the violation of the rights to good living and nature due to illegal mining activities in the parish of Buenos Aires, province of Imbabura. It was developed under a quantitative approach and a documentary-bibliographic design, making a critical analysis of various sources such as scientific research, articles, laws and refereed works. The study population was 1,893 inhabitants, according to the 2010 census, selecting a sample of 80 people through intentional and random sampling. The results show that, despite state measures, this illegal activity has left irreparable damage, affecting the inhabitants and the natural environment
Effects Of Contamination By The Waste Dump In Babahoyo And Its Impact On The Right To A Healthy Environment
Authors: Coello Avilés Esther Maricela , Coloma Morales Duval Arturo
Published: January 2025

The environmental contamination generated by the open-pit waste dump in Babahoyo seriously affects public health, quality of life and the population's right to a healthy environment. The accumulated waste contaminates the soil, water and air, causing illnesses and deteriorating well-being, especially among the most vulnerable groups. The research adopts a mixed approach to analyze this phenomenon, combining qualitative and quantitative methods, with a correlational, descriptive and propositional scope. It is proposed to implement an ordinance to manage waste, encourage recycling, promote environmental education and strengthen collaboration between authorities
Preconceptional Reproductive Risk in women of childbearing age. Preventive, clinical and epidemiological approach
Authors: Pérez Márquez Lázara Caridad , Lescalle Ortiz Yoleiny de la Caridad , Casabella Martínez Silvio , Chacón Alpí Angel Oshumaré
Published: January 2025

Introduction: Prevention of preconceptional maternal risk is important to avoid complications and death during the reproductive process. Methods: An observational, descriptive and cross-sectional study was carried out from 2023 to April 2024 in women of childbearing age with preconceptional reproductive risk (RRPC) residing in the community served by the Pedro Borrás Astorga Polyclinic in the municipality of Pinar del Río, in the province of the same name. The universe consisted of 5761 women of fertile age between 15 and 49 years old from the family doctor's and nurse's offices of the aforementioned polyclinic who gave their consent to participate in the research. The data collection was carried out from the controls recorded in the individual medical records and information provided by the statistics department of the center, in addition to the survey applied by the author of the research to a sample of 606 women with RRPC, with prior informed consent (Annexes 1 and 2).Results: the current trends in the development of the object of study were identified, determining irregularities that made possible the transformation of the inadequacies Conclusions: The risk factors mostly associated with RRPC in our polyclinic were determined, which will allow the establishment of future strategies in a problem yet to be solved
Comparison of healing activity between azadirachta indica and moringa oleifera seed oils on cutaneous wounds in wistar rats
Authors: López Barrera Alexandra , Burbano Gómez Zoraida , Valdiviezo Rogel Carlos Jefferson , Sarmiento Tomalá Glenda Marcela , Jimenez Granizo Francisca Patricia , Soledispa Cañarte Pilar Asunción
Published: January 2025

Medicinal plants are natural remedies that bring benefits to the organism. Phytomedicine’s production has increased in the last decades due to the adverse reactions of designer drugs. This research focused on basic principles that rule the scarification of wounds as a natural response to the damages produced with specific functions of tissue restoration and integrity. For this reason the acceleration of the scarring effect with Azadirachta indica seeds oil and Moringa was studied. Nine groups of animals were made: normal, negative and negative control, three Neem groups, three Moringa groups (30, 60.120 µl) respectively. The wound was made after placing the animal under anesthesia using the punch method. For seven days, these groups were observed while they received the treatment. After the test, the animals were euthanized, and scarred skin tissue samples were collected for histopathologic tests. As a result, after the second day, the concentration of Neem tested 4,38 mg/ml showed humity and inflammation of 73% and 76% respectively, which eventually dropped to zero. The presence of crust in the third day was 20% and in the sixth, 100%. On the other hand, concerning to the Moringa oil 4,48 mg/ml, no significant changes could be seen in any of the evaluated parameters. Comparing the percentages of the crust coverage among these groups, it can be said that: natural scarification(B) 10% the third day and 40% at the end of the research. The subjects treated with neem (E) 30% the third day and 100% the sixth, while D, F 80% the same day and 100% the seventh, the same as seen in C (iodine). The groups with Moringa presented 10% in the third day and 60% by the end. In conclusion, the groups with neem showed acceleration in the scarification process within the experimentation period.
Telework and occupational diseases. A systematic review
Authors: González de Paz Aixa , Paz-Gañan Carlos , Aguiar Henry , Coronado Hilfel , De Nobrega Alberto , Escalona Evelin
Published: January 2025

This systematic review identifies occupational diseases that are related to teleworking, a work phenomenon that has grown significantly, especially after the COVID-19 pandemic. It establishes the context of teleworking and its impact on workers' health, highlighting both its benefits and risks. The aim of the study was to identify and analyse the pathologies associated with teleworking, as well as the psychosocial and ergonomic factors that influence occupational health. The findings show an increase in musculoskeletal disorders, mental health problems, visual disturbances and increased cardiovascular risks, attributable to inadequate working conditions and work overload. In conclusion, the importance of implementing prevention and health promotion strategies in teleworking environments is underlined, suggesting the need for organisational policies that favour the comprehensive well-being of employees, especially in vulnerable populations such as women.
The Heberprot-P in the 21st century
Authors: Hernández Díaz Aida Rosa , Hernández Rojas Ana Lidia , Hernández Rojas Ana Lidia , Moreira Martínez Marta Maricel , Rojas Reyes Gladys , Delgado Estrada Yosmany
Published: January 2025

Introduction: Heberprot-P, considered the medicine of the 21st century for the healing of diabetic feet, is emerging as a promising technique for the repair of destroyed or damaged tissues. Objective: To present the results of the use of intra- and perilesional Heberprot-P in complex ulcers in the province of Pinar del Rio, Cuba from 2022 to 2024. Methods: a descriptive, retrospective, cross-sectional study of the use of Heberprot-P 75 mcg was developed. intra and perilesional in patients with complex ulcers from January 2022 to March 2024 in the province Pinar del Río, Cuba, with a total of 8482 lesions and an intentional sample of 181 complex ulcers. Inclusion criteria: presence of complex ulcers in the lower limbs. Exclusion criteria: those who did not meet the inclusion criteria with prior signing of the informed consent. Results: non-complex ulcers were more frequent, for 98%, diabetic foot represented 81% of complex ulcers, these with a higher rate of major amputation, hospitalization and intralesional infiltrations, with 18 doses (6 weeks, 42 days ) to achieve total granulation, correspondingly the time for closure by secondary intention was longer, 6 weeks after its application (84 days in total). Conclusions: the use of intra- and perilesional Heberprot-P is an effective therapy to accelerate granulation and closure by secondary intention of complex wounds that are difficult to heal.
SISTEM INFORMASI PENDAFTARAN KULIAH KERJA NYATA (KKN) BERBASIS WEB PADA UNIVERSITAS BANGKA BELITUNG
Authors: Nissa Reni Reina Nurul Ainun , Oktarmila Yezika
Published: January 2025

Kuliah Kerja Nyata (KKN) is a mandatory program to implement the Tri Dharma of Higher Education, particularly in community service. Currently, the registration process for KKN at Bangka Belitung University is still done manually. The manual systems have led to various problems, such as data management issues, verification, data duplication, and the availability of information for students regarding their registration status. This research aims to develop an information system for the registration of the Community Service Program (KKN) that can be accessed via the Internet. This research uses the Waterfall system development method with stages of needs analysis, design, coding, implementation, and maintenance. The research results in a prototype of the KKN registration information system. The implementation of the new system shows that the proposed system can improve the efficiency of the registration process, reduce data entry errors, and allow all users to access information quickly.
Pharmacokinetic and pharmacodynamic effects of Withania somnifera (L.) Dunal (ashwagandha) and carbamazepine combination in rats
Authors: Alsabaa Zein Husam , Abu-Qatouseh Luay , Mansoor Kenza , El-Hajji Feras Darwish , Bardees Razan , Aljabr Ghofran , Omari Khaled W. , Mallah Eyad
Published: January 2025

Context: Withania somnifera, also known as ashwagandha, has antibacterial, anti-inflammatory, anticonvulsant, and anti-diabetic properties and reduces stress. Carbamazepine is one of the most used antiepileptic medications for treating epilepsy.
Aims: To investigate the pharmacokinetics and pharmacodynamics of carbamazepine versus W. somnifera extract combination in vivo in healthy rat plasma using high-performance liquid chromatography.
Methods: The carbamazepine levels were analyzed using validated high-performance liquid chromatography. The gamma-aminobutyric acid in the serum was performed using an enzyme-linked immunosorbent assay.
Results: Combining W. somnifera and carbamazepine resulted in a significant increase in urine volume. There was a slight increase in brain size. It took two to four hours to reach the maximum concentration, a substantial rise. After treatment with W. somnifera root extract, in combination with carbamazepine and carbamazepine alone, the concentrations of the gamma-aminobutyric acid in the serum sample were 596, 452, and 505 ng/mL, respectively. Therefore, the serum rat group that received a combination therapy showed a decrease in the gamma-aminobutyric acid level.
Conclusions: Compared to the combination of carbamazepine and W. somnifera extract, the time required to reach the maximum concentrations of both the drug and the extract was significantly increased, and the levels of gamma-aminobutyric acid concentration decreased. This could affect the rate at which the stomach emptied, reduce absorption, or change how the medication was absorbed.
Pembentukan Desa Peduli Sampah Melalui Gerakan Pilah Pilih Sampah (PPS) dan TPS 3 R di Desa Kasang Pudak Kabupaten Muara Jambi
Authors: Sondang Siahaan  , Supriatna
Published: January 2025

Masalah pengelolaan sampah di Indonesia menjadi isu penting yang berdampak pada lingkungan dan kesehatan masyarakat. Desa Kasang Pudak, Kabupaten Muara Jambi, menghadapi tantangan pengelolaan sampah akibat rendahnya kesadaran masyarakat dan minimnya fasilitas pendukung. Program "Desa Peduli Sampah" dirancang untuk mengatasi permasalahan tersebut melalui Gerakan Pilah Pilih Sampah (PPS) dan pengoptimalan Tempat Pembuangan Sampah 3R (Reduce, Reuse, Recycle). Metode pelaksanaan meliputi penyuluhan, promosi kesehatan, dan pembangunan komposter biopori, yang melibatkan masyarakat, pemerintah desa, dan pengelola TPS 3R. Program ini dilakukan dalam rentang waktu Januari hingga Desember 2024. Hasilnya menunjukkan peningkatan signifikan pada pengetahuan masyarakat tentang pemilahan sampah, dari 24% yang memiliki pengetahuan tinggi sebelum intervensi menjadi 85% setelahnya. Kesimpulannya, program ini berhasil meningkatkan kesadaran masyarakat terhadap pengelolaan sampah dan memanfaatkan sampah sebagai sumber daya ekonomis. Dengan keberlanjutan program, Desa Kasang Pudak berpotensi menjadi model pengelolaan sampah berbasis komunitas yang dapat direplikasi di daerah lain.
Aprovechamiento del sargazo a través de la incorporación de carbonización hidrotermal y digestión anaerobia: una solución sustentable para la gestión de biomasa marina
Authors: Balderas-Caballero Israel de Jesús , Vallejo-Cantú Norma Alejandra , Méndez-Contreras Juan Manuel , Rosas-Mendoza Erik Samuel , Alvarado-Lassman Alejandro
Published: January 2025

Este estudio trata sobre la apreciación del sargazo a través de la incorporación de la carbonización hidrotermal (HTC) y la digestión anaerobia (DA). La biomasa obtenida en Playa del Carmen, México, se sometió a HTC en un reactor automatizado, empleando temperaturas de 180 °C, 200 °C, periodos de reacción de 60 y 120 minutos y relación sólido/ agua de 1:1 y 1:3 (p/p) respectivamente. La HTC produjo hidrochar, agua de proceso y gas de síntesis. El hidrochar evidenció una potencia calorífica superior (HHV) de 13.75 a 18.92 MJ/kg, en cambio, el agua de proceso mostró un HHV de 12.36 a 15.80 MJ/kg y un potencial de producción de metano de hasta 723.56 mL CH4/g SV. La combinación de HTC-DA mejora la utilización energética del sargazo, empleando el hidrochar como biocombustible sólido y el agua de proceso como medio para la generación de biogás. Esta perspectiva proporciona una alternativa factible para atenuar los problemas ecológicos y económicos provocados por las grandes llegadas de sargazo, fomentando la sostenibilidad en zonas costeras. Además, la investigación resalta la relevancia de continuar explorando tecnologías híbridas que incrementen la eficacia y el beneficio ambiental en la gestión de biomasa marina.
Estos hallazgos favorecen la creación de soluciones innovadoras ante un reto mundial en aumento.
The two-dimensional divisor function over Piatetski-Shapiro sequences
Authors: Tangsupphathawat Pinthira , Srichan Teerapat
Published: January 2025

We study the values of the two-dimensional divisor function and its related functions on the elements of a Piatetski-Shapiro sequence.
Valuation and Volatility of Virtual Properties in Metaverse: Exploring New Market Opportunities and Speculative Dynamics Based on Decentraland
Authors: Narowski Dawid , Santos Celso , Borowski Lukasz , Apollo Michal , Maciuk Kamil
Published: January 2025

Existing reality has been repeatedly subjected to multifaceted and multidimensional analyses. However, alongside it, a virtual reality exists, populated with virtual art, objects in games, cyber-pets, and virtual properties, collectively worth billions of real dollars. This virtual reality is associated with the concept of the 'metaverse' (a term derived from 'meta' and 'universe'), signifying a space that facilitates life in a virtual world. This space has a quantifiable value and is traded on specially designed platforms. The study focuses on the largest of these platforms, Decentraland, where users can purchase virtual properties using a cryptocurrency called MANA. Based on an analysis of 207 property transactions, the study examines whether these properties can be appraised using typical approaches applicable to “real” properties. It explores the relationship between spatial attributes, property price, and price volatility over time, calculating correlation coefficients for this purpose. Additionally, the study investigates the number of property sales, including multiple sales, and the proportion of properties with ITEMs on them, determining the correlation coefficients between price and parcel attributes. This study is the first to accomplish what researchers in the real estate market have long been doing. The results distinctly show that the virtual real estate market is governed by different factors compared to the traditional market, with property price and location remaining as two crucial aspects in the decision-making process for purchasing a property.
Successful Management of Pseudo-Ludwig Angina from Supratherapeutic Warfarin Use: A Case Report
Authors: Ekin Utku , Hazari Arham , Alyassin Nizar , Alcantara Alan , Azzam Moh'd Hazem , Ismail Mourad
Published: January 2025

Introduction: Ludwig angina is a potentially fatal condition characterized by soft tissue infection of the submandibular, sublingual, and submental compartments. Pseudo-Ludwig angina is a rare condition characterized by sublingual swelling of non-infectious etiology, typically in the setting of supratherapeutic anticoagulation. However, other etiologies, such as angioedema and trauma, have been described. Case Report: We present the case of a 59-year-old female with pseudo-Ludwig angina that developed in the setting of warfarin therapy and supratherapeutic international normalized ratio. She presented with sublingual swelling and dysphagia. She was successfully treated with dexamethasone, vitamin K, and fresh frozen plasma. The most appropriate imaging modalities in these cases are contrast-enhanced computed tomography (CT) and CT angiogram. If a hematoma is present, antibiotics for anaerobic coverage are also appropriate. Conclusion: We hope this case sheds light upon this rare pathology and ultimately hastens recognition and proper intervention.
Polyarticular Septic Arthritis Caused by Haemophilus Influenzae in an Asplenic Patient: A Case Report
Authors: Desarden Roberto , Caloia Roya Z
Published: January 2025

Introduction: Prevalence of serious infections from Haemophilus influenzae has diminished over the last few decades because of immunizations against the most virulent serotype. However, over the last few years a handful of septic arthritis cases secondary to H influenzae have been documented. Most of the cases documented are in the pediatric and unimmunized population. This is a case of polyarticular septic arthritis in a 69-year-old male who presented with syncope and ankle pain. Case report: A 69-year-old male presented to the emergency department after a syncopal event at home and complaining of right ankle pain. He was tachycardic and tachypneic on presentation and had an erythematous painful right ankle and right elbow. Aspiration of both joints produced purulent aspirate that grew H influenzae. Antibiotics were started, and the patient was taken to the operating room for emergent joint lavage. The patient made a full recovery and was discharged home with a peripherally inserted central catheter line for continued intravenous (IV) antibiotics. Conclusion: Our case highlights an atypical presentation for a case of polyarticular septic arthritis caused by H influenzae. We were unable to rule out endocarditis as a source of the bacterial seeding, and the patient improved with IV antibiotics and surgical lavage of the affected joints.
Serratus Anterior Plane Block for Procedural Anesthesia for Pigtail Tube Thoracostomy: A Case Series
Authors: Lopez Edward , Sahni Raghav , Cooper Maxwell , Shalaby Michael
Published: January 2025

Introduction: Pneumothoraces are frequently treated by emergency physicians. Tube thoracostomy, the definitive treatment for a spontaneous pneumothorax, is associated with significant pain. Analgesia prior to tube thoracostomy often involves the administration of opioids and local infiltration of anesthetics. Thus far, regional anesthesia prior to pigtail tube thoracostomy in the emergency department (ED) has not been well described; it offers promise in alleviating pain associated with this procedure. Due to its ability to anesthetize all or most of the structures associated with tube thoracostomy—skin, serratus anterior muscles, intercostal muscles, and the parietal pleura—the serratus anterior plane block (SAPB) is a potentially promising fascial plane block prior to pigtail tube thoracostomy. Case Series: We present three cases of patients in the ED who received a SAPB and had nearly complete or complete anesthesia during pigtail tube thoracostomy. Conclusion: Pigtail tube thoracostomies are commonly performed in the ED and can be associated with significant pain despite a multimodal approach to pain management. The SAPB offers a safe and effective approach to anesthesia for patients in the ED undergoing a pigtail tube thoracostomy.
"I'm Seeing Dead People": A Case Report on Salicylate Poisoning in a Patient with Hallucinations
Authors: Meyers Jessica , McCormick Sean , Levy Phillip , Twiner Michael
Published: January 2025

Introduction: Salicylate poisoning remains one of the most common global accidental overdoses and poses a considerable health threat. Typical presentations for salicylate overdoses include nausea, vomiting, and abdominal pain as well as tinnitus, tachypnea, fever, and dehydration resulting in a concomitant metabolic acidosis and respiratory alkalosis. This may progress to a predominance of neurological symptoms such as mental status changes, confusion, delirium, and hallucinations. Case Report: We describe the case of an accidental, sub-chronic overdose (up to 7.5 grams/day for multiple weeks; ~75 milligrams/kilogram/day) that resulted in predominantly neurological symptoms (ie, tinnitus and hallucinations, including the patient reporting “seeing dead people”) but without the more typical findings classically associated with salicylate toxicity. The patient was started on a sodium bicarbonate drip; after two days, symptoms completely resolved, and she was safely discharged home. Conclusion: This case serves as a reminder for physicians to have a high index of suspicion for chronic toxicities including salicylates in patients who present as acute psychosis or altered mental status of unknown etiology.
Gastric Outlet Obstruction as a Result of an Inguinal Hernia
Authors: Wohlford Luke , Bounds Rich
Published: January 2025

Case Presentation: We present a case of a 79-year-old male with gastric outlet obstruction resulting from a stomach herniation through a large left inguinal hernia. Discussion: Stomach-containing inguinal hernias are a rare cause of gastric outlet obstruction. Treatment options range from conservative to surgical management. Once identified with imaging, prompt treatment should be initiated to prevent incarceration, strangulation, and gastric necrosis.
Challenges and Outcomes of Thrombolytic Therapy in Acute Ischemic Stroke: The Iranian Perspective
Authors: Khanmirzaei Amir , Azarinoush Gelareh , Akbarimehr Melika , Farzan Nina , Mousavi Ali
Published: January 2025

Background: Acute ischemic stroke (AIS) is a leading cause of mortality and long-term disability worldwide. In Iran, AIS tends to occur nearly a decade earlier than in developed nations, presenting unique challenges. Intravenous recombinant tissue plasminogen activator (IV-rtPA) is an effective thrombolytic therapy for AIS, but various factors limit its utilization. Objectives: This study aimed to identify the barriers to the administration of IV-rtPA in AIS patients at Shahid Beheshti Hospital in Qom, Iran. Methods: A cross-sectional descriptive-analytical study was conducted on AIS patients admitted between November 2021 and September 2022. A total of 322 patients were screened, and 178 met the inclusion criteria. Data on demographic characteristics, stroke severity (NIHSS score), comorbidities, onset-to-door time, and reasons for not receiving IV-rtPA were analyzed using SPSS version 22. Results: Of the 178 patients, 87 (48.9%) received IV-rtPA, while 91 (51.1%) did not. The primary reasons for withholding thrombolysis were clinical improvement (37.4%), late hospital arrival beyond 4.5 hours (24.2%), lack of consent (20.9%), the physician's conservative approach (11%), and mild progression of stroke symptoms (6.6%). A significant correlation was found between NIHSS score and reasons for non-receipt of therapy (P < 0.001). Patients with a prior stroke history were more likely to experience delays due to a physician’s conservative approach (28.6% vs. 5.7%, P < 0.01). Barriers to thrombolysis were also associated with lower education levels and a lack of public awareness about stroke symptoms. Conclusions: Delayed hospital admission and lack of consent were the leading barriers to IV-rtPA administration. Public awareness campaigns emphasizing the urgency of recognizing stroke symptoms and seeking timely medical care are crucial to improving thrombolysis rates and reducing AIS-related disabilities in Iran.
Assessing the Emergency Medicine Specialists' Knowledge Regarding Thrombolytic Therapy in Ischemic Stroke Patients
Authors: Shams Vahdati Samad , Ala Alireza , Sadeghi Hokmabadi Elyar , Afsar Elham , Shiri Fatemeh , Tahmasbi Fateme , Fathalizadeh Arezoo
Published: January 2025

Background: Stroke is a major health concern worldwide, and timely intervention is crucial for improving outcomes in ischemic stroke patients. Emergency specialists play a critical role in managing these patients, yet gaps in their knowledge of stroke symptoms, risk factors, and thrombolytic therapy can cause delays in treatment, ultimately impacting patient outcomes. Objectives: This study aimed to evaluate the knowledge of emergency medicine specialists in Tabriz, Iran, regarding stroke symptoms, risk factors, and therapeutic interventions, with a specific focus on thrombolytic therapy. Methods: A survey study was conducted with 30 emergency medicine specialists from hospitals in Tabriz, using a structured questionnaire for data collection. Participants were selected through simple random sampling. The questionnaire assessed knowledge of common stroke symptoms, risk factors, and management protocols, including the use of tissue plasminogen activator (tPA). The validity and reliability of the tool were established through expert review and a pilot study. Data were analyzed using descriptive statistics and Pearson correlation, with a significance level set at P < 0.05. Results: The study revealed that participants had limited knowledge of stroke symptoms, with most identifying only 4 out of 10 common symptoms. While high blood pressure and heart disease were widely recognized as risk factors (100%), less common factors, such as stress and heredity, were poorly identified. Regarding management, 97% of participants were aware of tPA, but none correctly identified all three treatment strategies (tPA, aspirin, and surgery). Additionally, fewer than 60% of participants prioritized calling emergency medical services (EMS) as the first step in stroke management. Conclusions: The findings underscore significant gaps in emergency specialists' knowledge of stroke symptoms, risk factors, and management strategies, particularly concerning thrombolytic therapy. Targeted educational interventions are essential to enhance emergency medicine specialists' understanding of stroke care and improve patient outcomes.
The Effectiveness of Child-Parent Relationship Therapy on Social Anxiety and Self-esteem in Children with Attention Deficit Hyperactivity Disorder
Authors: Nasernejad Kian , Johari Fard Reza , Ehteshamzadeh Parvin , Bakhtiarpour Saeed , Mohebbi Nouredinvand Mohammad Hossein
Published: January 2025

Background: Children with attention deficit hyperactivity disorder (ADHD) often experience significant challenges with social interactions and self-worth. Given the potential impact of these difficulties on their overall well-being and future outcomes, understanding effective interventions is crucial. Objectives:: The present study aimed to investigate the efficacy of child-parent relationship therapy (CPRT) on social anxiety and self-esteem in children with ADHD. Methods: This quasi-experimental study employed a pre-test-post-test design with a control group. The population included all children diagnosed with ADHD in Amol city in 2023. A sample of 44 children was selected using a convenience sampling method and randomly assigned to experimental (n = 22) and control (n = 22) groups. The Liebowitz Social Anxiety Scale and Children's Self-Esteem Questionnaire were used to collect data. The experimental group received 10 sessions of CPRT, each lasting 90 minutes. The control group did not receive any intervention and served as a waitlist control. Data analysis was conducted using analysis of covariance (ANCOVA). Results: For social anxiety, the mean score in the CPRT group decreased from 90.27 ± 4.71 at the pre-test to 49.73 ± 5.57 at the post-test, while the control group showed minimal change (pre-test mean: 90.86 ± 5.58; post-test mean: 88.41 ± 6.02) (P < 0.001). Similarly, self-esteem scores in the CPRT group increased from a mean of 35.32 ± 3.60 at the pre-test to 63.59 ± 5.34 at the post-test (P < 0.001). The results indicated that CPRT significantly improved social anxiety and self-esteem in children with ADHD at the post-test stage (P < 0.001). Conclusions: The CPRT shows promise in improving social anxiety and self-esteem in children with ADHD. Reduced anxiety can lead to better social interactions, academic performance, and extracurricular involvement. Higher self-esteem can boost self-image, motivation, and resilience. More research is needed to understand the long-term benefits of CPRT.
 Helicobacter pylori Infection and Non-steroidal Anti-inflammatory Drugs Mediated Gastric Ulcer: Insights into Efficacy and Strategies for Gastroprotective Treatments and Disease Management
Authors: Lv Zhitiao , Fang Shaoyu , Wang Yan
Published: January 2025

Context: Helicobacter pylori infection and the use of non-steroidal anti-inflammatory drugs (NSAIDs) are the primary etiological factors contributing to gastric ulcer disease, characterized by mucosal erosions in the stomach. This condition remains a significant global health challenge, particularly in low- and middle-income countries, where it substantially contributes to morbidity and premature mortality. Complications such as gastrointestinal bleeding and perforation exacerbate the disease burden, underscoring the need for effective preventive and therapeutic strategies. Objectives: To evaluate the effectiveness of proton pump inhibitors, prostaglandin analogues, and histamine-2 (H2) receptor antagonists in preventing and healing gastric ulcers caused by H. pylori and NSAID use. The study aims to identify optimal treatments and explore patient-specific responses for improved, personalized therapy. Methods: This systematic review and meta-analysis evaluated the efficacy of gastroprotective treatments, including proton pump inhibitors (PPIs), prostaglandin analogues, and histamine-2 receptor antagonists (H2RAs), in preventing and healing gastric ulcers. A comprehensive search was conducted across PubMed, Embase, and the Cochrane Library. Inclusion criteria focused on Randomized Controlled Trials (RCTs) assessing these treatments in patients with gastric ulcers. Quality assessment was performed using the adapted Newcastle–Ottawa Scale. The DerSimonian and Laird random-effects model was employed to determine pooled effect sizes, with heterogeneity assessed using Cochran’s Q and I² statistics. All analyses were conducted using Stata/MP 17.0. Results: The search identified 2,687 records, with 116 studies meeting the inclusion criteria after rigorous screening and quality assessment. The meta-analysis included studies on PPIs, prostaglandin analogues, and H2RAs, involving 18,042 participants in the treatment groups and 13,255 in the control groups. PPIs significantly reduced the incidence of gastric ulcers (log odds ratio = -1.17, 95% CI: -1.97 to -0.37, P < 0.001) with high heterogeneity (I² = 98.13%). Prostaglandin analogues (log odds ratio = -1.61, 95% CI: -2.49 to -0.73, P < 0.001) and H2RAs (log odds ratio = -0.86, 95% CI: -1.92 to 0.20, P < 0.001) also demonstrated significant protective effects despite high heterogeneity. Conclusions: Gastroprotective treatments, particularly PPIs and prostaglandin analogues, are effective in reducing gastric ulcer incidence. The high heterogeneity among studies suggests the need for individualized treatment approaches. Further research is warranted to refine protocols and optimize patient-specific therapies.
First Case of Vulvovaginal Trichosporonosis Due to Trichosporon coremiiforme and Review of Recent Literature
Authors: Ranjbar Golafshani Fatemeh Zahra , Kermani Firoozeh , Abbaszadeh Godarzi Soheila , Ahangari Maryam , Mahdavi Omran Saeid
Published: January 2025

Introduction: Trichosporon spp. are emerging basidiomycetous yeasts that can cause both superficial and invasive infections. Trichosporon coremiiforme is phylogenetically closely related to T. asahii. It has been isolated from various clinical samples; however, to date, there have been no reports of vulvovaginal infections caused by T. coremiiforme. This case report contributes to our understanding of T. coremiiforme infections and its potential to cause invasive infections in immunocompetent patients. Case Presentation: A 35-year-old woman with vulvovaginitis, a history of recurrent infections, and menorrhagia was referred to Babol Medical Center. The infection was confirmed through recultivation at two different sampling times, and the strain was identified as T. coremiiforme using ribosomal DNA sequencing. The patient was treated with voriconazole and miconazole. Conclusions: This is the first reported case of vulvovaginal trichosporonosis caused by T. coremiiforme in an immunocompetent patient. It underscores the importance of prompt and accurate identification of infections, even in immunocompetent individuals, for timely treatment.
The Effect of Levetiracetam on Improving Cognitive Impairment in Relapsing-Remitting Multiple Sclerosis Patients: A Pilot Double-Blind Randomized Placebo-Controlled Clinical Trial
Authors: Sharif Maryam , Honarmand Hooshyar , Vahabizad Fahime , Sahraian Mohammad Ali , Mojtahedzadeh Mojtaba , Navardi Samira , Rezaeimanesh Nasim , Davoudi Efat , Saeedi Roghayeh , Sadeghi Kourosh , Naser Moghadasi Abdorreza
Published: January 2025

Background: Cognitive impairment has been identified in all stages and affects all subtypes of multiple sclerosis (MS) (40 - 65% of people with clinically definite MS). A defined therapeutic strategy has not yet been determined. Objectives: This study aimed to assess the efficacy of levetiracetam (LEV) to improve cognitive impairments in patients with relapsing-remitting MS (RRMS). Methods: A Pilot randomized; double-blinded, placebo-controlled clinical trial was conducted. The patients with a definite diagnosis of RRMS treated with first-line drugs. They were assigned into two groups; LEV and the placebo for four months. The primary outcome was the changes in cognitive domains based on the minimal assessment of cognitive function in multiple sclerosis (MACFIMS) compared to baseline. The MACFIMS was accomplished by seven tests: California verbal learning test-II (CVLT-II), paced auditory serial addition test (PASAT), symbol digit modalities testing (SDMT), brief visuospatial memory test-revised (BVMT-R), delis-Kaplan executive function system (D-KEFS), controlled oral word association test (COWAT), and judgment of line orientation (JLO). Results: A total of 32 patients entered the study and 28 patients completed the trial. The change in JLO score in the LEV group was significantly greater than in the placebo group (P-value = 0.03). After intervention in the LEV group, the SDMT and JLO scores were significantly higher than the baseline scores. Conclusions: This is the study to evaluate the effects of LEV on cognitive disorders in patients with MS. Levetiracetam was significantly effective in improving the JLO and SDMT scores in patients with RRMS compared to the placebo group.
Mi Trayectoria como Estudiante y Profesor en la UAN
Authors: Jara Ulloa Francisco Javier
Published: January 2025

This article shows my career within the Universidad Autónoma de Nayarit (UAN) from 1993 to the present (2024), first as a student and graduate of the courses: Industrial Chemical Engineering (November, 1998) and Bachelor's Degree in Educational Mathematics (July , 2000). Later as a teacher from 2008 to 2017 at the Secretariat of Higher Secondary Education, working on the design of educational materials and reagents in the area of ​​Mathematics for internal academic competitions and entry to the Higher Secondary Level. From 2017 to the present as Professor of Mathematics and Researcher (PRODEP, 2019 - 2025 and SNII 2024 - 2027) in the Academic Program of Mechanical Engineering in the Academic Unit of Basic Sciences and Engineering. In the years 2016, 2021, 2022 and 2023 I have participated as a professor of the Statistics course for the Master's Degree in Public Health in the area of ​​Health Sciences with registration in SNP CONAHCYT
Unidad Académica de Contaduría y Administración (UACyA): Testimonio de excelencia educativa
Authors: Bogarín Correa María Romelia
Published: January 2025

Desde su creación, la Unidad Académica de Contaduría y Administración  de la Universidad Autónoma de Nayarit, se ha comprometido en la formación de profesionales altamente capacitados en los programas que ofrece. Y es, a través de la enseñanza de habilidades y conocimientos que esta noble institución ha dotado a sus egresados con las herramientas necesarias para desenvolverse productivamente en el mundo laboral. Es importante resaltar también el trabajo y dedicación que día día lleva a cabo su personal para que se logren sueños y metas de miles de jóvenes motivados por tener un mejor futuro. El objetivo de esta investigación es realizar una recopilación bibliográfica que permita conocer el contexto en el que se ha desarrollado, los programas académicos con que actualmente cuenta, su infraestructura, proyectos de responsabilidad social, agenda 2030 y cuerpos académicos; dando así testimonio de su desarrollo y desempeño progresivos
Compañerismo estudiantil: estrategia para no desertar de la Unidad Académica de Ciencias Básicas e Ingenierías
Authors: HERNANDEZ JUAN LUIS
Published: January 2025

In this article I address one of the vast experiences that I had as a student of the Academic Unit of Basic Sciences and Engineering in the period 2005 - 2010, which describes how student camaraderie had very positive effects on the university scaffolding to be able to face different shortcomings (economic and academic) to name a few. It is worth mentioning that it focuses on academic deficiency, which has to do with the level and speed of mathematics and physics in an engineering school, this being one of the causes of school dropouts in these areas, however, it is explained how through collaboration with classmates it was possible to meet challenges, which at that moment were of great joy and pride, since the academic deficiency was able to be solved and in that journey it was possible to detect an error in a book of university physics