bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Comorbidities and Smoking on the Outcome in Aneurysmal Subarachnoid Hemorrhage
Authors: Hammer Alexander , Steiner Anahi , Ranaie Gholamreza , Yakubov Eduard , Erbguth Frank , Hammer Christian M. , Killer-Oberpfalzer Monika , Steiner Hans , Janssen Hendrik
Published: August 2018

The intention of this observational study is to show the significant impact of comorbidities and smoking on the outcome in aneurysmal subarachnoid hemorrhage (SAH). During this observational study 203 cases of treatment of ruptured intracranial aneurysms were analyzed. We examined and classified prospectively the 12 month outcome according to the modified Rankin Scale (mRS) considering retrospectively a history of smoking and investigated prospectively the occurrence of early and delayed cerebral ischemia between 2012 and 2017. Using logistic regression methods, we revealed smoking (odds ratio 0.21; p = 0.0031) and hypertension (odds ratio 0.18; p = 0.0019) to be predictors for a good clinical outcome (mRS 0–2). Age (odds ratio 1.05; p = 0.0092), WFNS Grade (odds ratio 6.28; p < 0.0001), early cerebral ischemia (ECI) (odds ratio 10.06; p < 0.00032) and delayed cerebral ischemia (DCI) (odds ratio 4.03; p = 0.017) were detected as predictors for a poor clinical outcome. Significant associations of occurrence of death with hypertension (odds ratio 0.12; p < 0.0001), smoking (odds ratio 0.31; p = 0.048), WFNS grade (odds ratio 3.23; p < 0.0001) and age (odds ratio 1.09; p < 0.0001), but not with ECI (p = 0.29) and DCI (p = 0.62) were found. Smoking and hypertension seem to be predictors for a good clinical outcome after aneurysmal SAH.
Nuclear connectin novex-3 promotes proliferation of hypoxic foetal cardiomyocytes
Authors: Hashimoto Ken , Kodama Aya , Sugino Miki , Yobimoto Tomoko , Honda Takeshi , Hanashima Akira , Ujihara Yoshihiro , Mohri Satoshi
Published: August 2018

Loss of cardiomyocyte proliferative capacity after birth is a major obstacle for therapeutic heart regeneration in adult mammals. We and others have recently shown the importance of hypoxic in utero environments for active foetal cardiomyocyte proliferation. Here, we report the unexpected expression of novex-3, the short splice variant of the giant sarcomeric protein connectin (titin), in the cardiomyocyte nucleus specifically during the hypoxic foetal stage in mice. This nuclear localisation appeared to be regulated by the N-terminal region of novex-3, which contains the nuclear localisation signal. Importantly, the nuclear expression of novex-3 in hypoxic foetal cardiomyocytes was repressed at the postnatal stage following the onset of breathing and the resulting elevation of oxygen tension, whereas the sarcomeric expression remained unchanged. Novex-3 knockdown in foetal cardiomyocytes repressed cell cycle-promoting genes and proliferation, whereas novex-3 overexpression enhanced proliferation. Mechanical analysis by atomic force microscopy and microneedle-based tensile tests demonstrated that novex-3 expression in hypoxic foetal cardiomyocytes contributes to the elasticity/compliance of the nucleus at interphase and facilitates proliferation, by promoting phosphorylation-induced disassembly of multimer structures of nuclear lamins. We propose that novex-3 has a previously unrecognised role in promoting cardiomyocyte proliferation specifically at the hypoxic foetal stage.
Effect of probiotic Bifidobacterium bifidum G9-1 on the relationship between gut microbiota profile and stress sensitivity in maternally separated rats
Authors: Fukui Hirokazu , Oshima Tadayuki , Tanaka Yoshiki , Oikawa Yosuke , Makizaki Yutaka , Ohno Hiroshi , Tomita Toshihiko , Watari Jiro , Miwa Hiroto
Published: August 2018

Although gut microbiota and early life events are likely involved in the development of irritable bowel syndrome (IBS), it remains unclear how these factors interact in the pathophysiology of IBS. In the present study, using rats subjected to maternal separation (MS) as a model of IBS, we investigated interrelationships among gut microbiota, stress susceptibility and intestinal permeability, and examined the effect of the probiotic Bifidobacterium bifidum G9-1 (BBG9-1) on those interrelationships. When compared with the controls at postnatal day 20, MS rats showed hypercorticosteronemia, enhanced intestinal permeability and changes in gut microbiota structure. All of these changes in MS rats were prevented by treatment with BBG9-1. Although the gut microbiota profile and basal serum corticosterone level did not differ between MS and control rats at postnatal day 56, MS rats showed hypersensitivity to restraint stress in terms of serum corticosterone level and fecal frequency. However, such hypersensitivity was not observed in MS rats treated with BBG9-1. These findings suggest that MS initiates the link between gut microbiota alteration and hypersensitivity to stress and that the triggering of this process can be prevented by the treatment with the probiotic BBG9-1.
UBXD1 is a mitochondrial recruitment factor for p97/VCP and promotes mitophagy
Authors: Bento Ana C. , Bippes Claudia C. , Kohler Corina , Hemion Charles , Frank Stephan , Neutzner Albert
Published: August 2018

Clearance of damaged mitochondria through mitophagy is critical for maintaining mitochondrial fidelity and the prevention of neurodegeneration. Here, we report on the UBX domain-containing, p97/VCP cofactor UBXD1/UBXN6/UBXDC2 and its role in mitophagy. Recognizing depolarized mitochondria via its C-terminal UBX domain, UBXD1 translocates to mitochondria in a Parkin-dependent manner. During Parkin-independent mitophagy, UBXD1 shows no mitochondrial translocation. Once translocated, UBXD1 recruits p97 to mitochondria via a bipartite binding motif consisting of its N-terminal VIM and PUB domains. Recruitment of p97 by UBXD1 only depends on the presence of UBXD1 on mitochondria without the need for further mitochondrial signals. Following translocation of UBXD1 to CCCP-depolarized mitochondria and p97 recruitment, formation of LC3-positive autolysosomes is strongly enhanced and autophagic degradation of mitochondria is significantly accelerated. Diminished levels of UBXD1 negatively impact mitophagic flux in Parkin-expressing cells after CCCP treatment. Thus, our data supports a model, whereby the p97 cofactor UBXD1 promotes Parkin-dependent mitophagy by specifically recognizing damaged mitochondria undergoing autophagic clearance.
Avian vision models and field experiments determine the survival value of peppered moth camouflage
Authors: Walton Olivia C. , Stevens Martin
Published: August 2018

Animal defensive coloration has long provided many important examples of evolution and adaptation. Of these, industrial melanism in the peppered moth is the classic textbook example of evolution in action, whereby dark and pale morphs suffer differential predation in polluted and unpolluted woodland based on their camouflage. Despite extensive work, a striking gap remains in that no study has ever objectively quantified their camouflage or related this directly to predation risk. Here we use image analysis and avian vision models to show that pale individuals more closely match lichen backgrounds than dark morphs. Artificial predation experiments in unpolluted woodland show 21% higher survival rates of pale than melanic individuals. Overall, we provide the strongest direct evidence to date that peppered moth morph frequencies stem from differential camouflage and avian predation, providing key support for this iconic example of natural selection.
Characterization of ZnO as substrate for DSSC
Authors: Mansilla Wettstein Candela , Sánchez Cristián G.
Published: August 2018

We present a complete analysis of the photoinjection process in 3 nm spherical ZnO nanoparticles with different dyes attached to their surface.
Hydrogen transfer through different crystal phases of nickel oxy/hydroxide
Authors: Elbaz Yuval , Furman David , Caspary Toroker Maytal
Published: August 2018

Hydrogen transfer is modeled for nickel hydroxide phases at several pathways and mechanisms.
Exploration of the unusual two-step volume phase transition of the poly(N-vinylcaprolactam-co-hydroxyethyl methacrylate) hydrogel
Authors: Su Gehong , Jia Liyang , Zhang Xueqian , Zhang Yulin , Deng Pengchi , Zhou Tao
Published: August 2018

It is important to investigate the phase transition mechanism of stimuli-sensitive hydrogels due to its great guiding significance for the application of stimuli-sensitive hydrogels in biomedical applications.
Comparing gas transport in three polymers via molecular dynamics simulation
Authors: Anderson Luke R. , Yang Quan , Ediger Andrew M.
Published: August 2018

Molecular dynamics (MD) simulation was employed to study the transport of methane and n-butane molecules in the bulk and interface region of polyethylene (PE), poly(4-methyl-2-pentyne) (PMP) and polydimethylsiloxane (PDMS).
A graphene-hidden structure with diminished light shielding effect: more efficient graphene-involved composite photocatalysts
Authors: Zhou Chaocun , Yang Yanming , Zhu Yueshuai , Ma Juanjuan , Long Jinlin , Yuan Rusheng , Ding Zhengxin , Li Zhaohui , Xu Chao
Published: August 2018

Hiding graphene sheets behind semiconductors can minimize their light shielding effect and further optimize the photocatalysis performance of graphene-involved composites.
Topological and network analysis of lithium ion battery components: the importance of pore space connectivity for cell operation
Authors: Lagadec M. F. , Zahn R. , Müller S. , Wood V.
Published: August 2018

Pore space connectivity is a useful metric for describing microstructure of lithium ion battery components.
Micro-droplet arrays for micro-compartmentalization using an air/water interface
Authors: Kunding Andreas H. , Busk Louise L. , Webb Helen , Klafki Hans W. , Otto Markus , Kutter Jörg P. , Dufva Martin
Published: August 2018

Here we present a water-in-air droplet platform for micro-compartmentalization for single molecule guided synthesis and analysis consisting of a flow-system hosting dense arrays of aqueous microdroplets on a glass surface surrounded by air.
Clinical significance of the immune microenvironment in ovarian cancer patients
Authors: Yang Lei , Wang Shiyuan , Zhang Qi , Pan Yi , Lv Yingli , Chen Xiaowen , Zuo Yongchun , Hao Dapeng
Published: August 2018

Tumor immune infiltrates of ovarian cancer were quite cohort and subtype dependent.
Electrochemically growth-controlled honeycomb-like NiMoO4 nanoporous network on nickel foam and its applications in all-solid-state asymmetric supercapacitors
Authors: Kumbhar Vijay S. , Nguyen Van Quang , Lee Yong Rok , Lokhande Chandrakant D. , Kim Do-Heyoung , Shim Jae-Jin
Published: August 2018

A honeycomb-like NiMoO4 nanoporous network electrode was synthesized on nickel foam using an electrodeposition method and used for the fabrication of asymmetric supercapacitors (ASCs).
Self-assembled three-dimensional architectures of VO2:Yb3+,Er3+ controlled synthesis and dual-power dependent luminescence properties
Authors: Zheng Wei , Wang Rui , Li Yuemei , Xu Yanling , Su Baoyu
Published: August 2018

The higher power-sensitization triggers welding of the structure, favoring energy transfer between nanoparticles in Er3+/Yb3+ co-doped VO2.
Synthesis of self-assembled PtPdAg nanostructures with a high catalytic activity for oxygen reduction reactions
Authors: Ud Din Muhammad Aizaz , Saleem Faisal , Zulfiqar Muhammad , Wang Xun
Published: August 2018

Oxygen reduction reaction-favoring PtPdAg hollow nanoparticle, nanodimer and nanowire catalysts are synthesized, all of which have been demonstrated to be promoting factors for the ORR. PtPdAg/C nanodimers exhibit excellent performance for the ORR with the highest mass activity.
A rationally designed Fe-tetrapyridophenazine complex: a promising precursor to a single-atom Fe catalyst for an efficient oxygen reduction reaction in high-power Zn–air cells
Authors: Yang Zheng Kun , Yuan Cheng-Zong , Xu An-Wu
Published: August 2018

High-performance single-atom iron anchored on an N-doped carbon catalyst is developed using a rationally designed Fe-tetrapyridophenazine complex as the precursor that is subsequently heat treated.
Design, synthesis, and biological evaluation of C7-functionalized DMXAA derivatives as potential human-STING agonists
Authors: Hwang Jihyun , Kang Taeho , Lee Janghyun , Choi Byong-Seok , Han Sunkyu
Published: August 2018

A strategy to diversely functionalize the C7-position of DMXAA has been developed as a means to discover potential human-STING agonists.
Building of neomycin–nucleobase–amino acid conjugates for the inhibition of oncogenic miRNAs biogenesis
Authors: Vo Duc Duy , Becquart Cécile , Tran Thi Phuong Anh , Di Giorgio Audrey , Darfeuille Fabien , Staedel Cathy , Duca Maria
Published: August 2018

Neomycin–nucleobase–amino acid conjugates bind to pre-miR-372 and inhibit Dicer-mediated processing thus leading to decreased levels of oncogenic miR-372 in vitro and in gastric adenocarcinoma cells.
Nanogel-like UCST triblock copolymer micelles showing large volume expansion before abrupt dissolution
Authors: Augé Amélie , Fortin Daniel , Tong Xia , Zhao Yue
Published: August 2018

A comprehensive study of the thermally induced large expansion in volume prior to the abrupt dissociation of the micelles of a novel UCST triblock copolymer.
Nickel(ii)-catalyzed tandem C(sp2)–H bond activation and annulation of arenes with gem-dibromoalkenes
Authors: Shi Yun , Li Meng-Sheng , Zhang Fangdong , Chen Baohua
Published: August 2018

A nickel(ii)/silver(i)-catalyzed tandem C(sp2)–H activation and intramolecular annulation of arenes with dibromoalkenes has been successfully achieved, which offers an efficient approach to the 3-methyleneisoindolin-1-one scaffold.
Enhanced H2 sorption performance of magnesium hydride with hard-carbon-sphere-wrapped nickel
Authors: Peng Dandan , Ding Zhenmin , Fu Yaokun , Wang Yu , Bi Jia , Li Yuan , Han Shumin
Published: August 2018

Magnesium hydride is regarded as one of the most ideal candidates for hydrogen storage, but its relatively high operating temperatures and slow kinetics always hinder its commercial applications.
Research on biocharviaa comprehensive scientometric approach
Authors: Li Yuening , Jiang Shanxue , Wang Ting , Lin Yingchao , Mao Hongjun
Published: August 2018

A comprehensive statistical study related to biochar was conducted by using the scientometric method.
Expanding pentafluorouranates: hydrothermal synthesis and characterization of β-NaUF5 and β-NaUF5·H2O
Authors: Chemey Alexander T. , Sperling Joseph M. , Albrecht-Schmitt Thomas E.
Published: August 2018

Two new sodium uranium(iv) pentafluorides eliminate the necessity of a copper catalyst in the synthesis of alkali metal uranium fluorides.
Four-coordinate triarylborane synthesis via cascade B–Cl/C–B cross-metathesis and C–H bond borylation
Authors: Yang Kai , Zhang Guan , Song Qiuling
Published: August 2018

We herein describe a tandem highly selective B–Cl/C–B cross-metathesis of two same or different arylboranes and C–H bond borylation to synthesize four-coordinate triarylboranes with broad substrate scope.
Computational investigation of microgels: synthesis and effect of the microstructure on the deswelling behavior
Authors: Moreno Angel J. , Lo Verso Federica
Published: August 2018

The microstructure of the microgel strongly affects the deswelling kinetics.
Impact of stereochemistry on rheology and nanostructure of PLA–PEO–PLA triblocks: stiff gels at intermediate l/d-lactide ratios
Authors: Yin Xuechen , Hewitt David R. O. , Quah Suan P. , Zheng Bingqian , Mattei Gerard S. , Khalifah Peter G. , Grubbs Robert B. , Bhatia Surita R.
Published: August 2018

Hydrogels of PLA–PEO–PLA display a striking enhancement of the stiffness at intermediate l/d ratio, demonstrating the impact of block stereochemistry on the rheology.
Super-adsorbent hydrogel for removal of methylene blue dye from aqueous solution
Authors: Hu Xiao-Sai , Liang Rui , Sun Guoxing
Published: August 2018

A novel poly(acrylic acid) (PAA)-based super-adsorbent nanocomposite hydrogel as an effective dye adsorbent is prepared using non-aggregated calcium hydroxide (Ca(OH)2) nano-spherulites (CNSs) as cross-linkers.
Efficient solar cells with enhanced humidity and heat stability based on benzylammonium–caesium–formamidinium mixed-dimensional perovskites
Authors: Liu Guozhen , Zheng Haiying , Xu Xiaoxiao , Zhu Liangzheng , Alsaedi Ahmed , Hayat Tasawar , Pan Xu , Dai Songyuan
Published: August 2018

2D/3D perovskite solar cells based on benzylammonium–caesium–formamidinium cations exhibited a PCE as high as 19.24% with superior humidity and heat stability.
Tunable luminescence of a novel organic co-crystal based on intermolecular charge transfer under pressure
Authors: Wang Jing , Li Aisen , Xu Shuping , Li Bao , Song Chongping , Geng Yijia , Chu Ning , He Jian , Xu Weiqing
Published: August 2018

In situ continuous tunable photoemission of an organic charge transfer cocrystal (9ACA-TFP) is achieved by applying high hydrostatic pressure, which is of significance in determining the CT interaction – photoemission property relation of organic co-crystals.
A pan-cancer study of the transcriptional regulation of uricogenesis in human tumours: pathological and pharmacological correlates
Authors: Saidak Zuzana , Louandre Christophe , Dahmani Samy , Sauzay Chloé , Guedda Sara , Chauffert Bruno , Chatelain Denis , Ceballos-Picot Irene , Galmiche Antoine
Published: August 2018

Uric acid (UA) is the end product of the catabolism of purines, and its serum levels are commonly increased in cancer patients. We aimed to explore the transcriptional regulation of tumour uricogenesis in human tumours, and relate uricogenesis with tumour pathological and pharmacological findings. Using data from The Cancer Genome Atlas (TCGA), we analysed the expression levels of xanthine dehydrogenase (XDH) and adenine phosphoribosyltransferase (APRT), two key enzymes in UA production and the purine salvage pathway, respectively. We found large differences between tumour types and individual tumours in their expression of XDH and APRT. Variations in locus-specific DNA methylation and gene copy number correlated with the expression levels of XDH and APRT in human tumours respectively. We explored the consequences of this differential regulation of uricogenesis. Tumours with high levels of XDH mRNA were characterised by higher expression of several genes encoding pro-inflammatory and immune cytokines, and increased levels of tumour infiltration with immune cells. Finally, we studied cancer drug sensitivity using data from the National Cancer Institute-60 (NCI-60) database. A specific correlation was found between the expression levels of APRT and cell sensitivity to the chemotherapeutic agent 5-fluorouracil (5-FU). Our findings underline the existence of great differences in uricogenesis between different types of human tumours. The study of uricogenesis offers promising perspectives for the identification of clinically relevant molecular biomarkers and for tumour stratification in the therapeutic context.
Optimization in landscape architecture
Authors: Banek Tadeusz , Krupiński Patryk , Dudkiewicz Margot
Published: August 2018

Contemporary architectural proposals usually have to meet many different criteria. The most important are functionality and aesthetics, as well as rationality understood as a reference to costs. In this approach, the architectural proposal appears as a solution to the typical task considered in the Multi-criteria Decision Theory in the discipline generally referred to as Optimization. The paper presents examples of sixteenthcentury garden compositions, to try to answer the question of what the then residents (aristocrats) and the creators who fulfilled their wishes, were guided by. The homeland of the Renaissance is Italy, and the characteristics of this style were: geometry of space in the form of axial arrangement of rooms, symmetry, sheared forms of evergreen plants, and motifs referring to mythology. The basis of the Renaissance garden composition is a simple network of roads and squares, strongly connected to the main building and the remaining garden architecture. Mathematical principles, such as golden division of the segment and the Fibonacci sequence, were used as a way to bring beauty and balance to a design. This style is characterized by clipped garden ground floors with boxwood and molded vegetation. Roses, tulips, peonies and lavender were planted between shaped hedges. The terrace arrangement of some gardens has forced the creation of additional structures, such as retaining walls, ramps, balustrades and stairs. The paper discusses the subject of the golden division and its share in individual garden compositions. The authors showed many mathematical relationships that architects used when designing the described garden assumptions.
Assessment of thermo-modernization in a multifamily building
Authors: Basińska Małgorzata , Koczyk Halina , Błotnicka-Smyk Aleksandra
Published: August 2018

This paper presents an evaluation of thermo-modernisation improvements applied over the years in the multi-family residential building. Those improvements have included the civil and mechanical activities. The civil activities were as follows: the application of the thermal insulation on the external walls and replacement of the windows. The mechanical activities were mainly focused on an adjustment of the heating system to the new reduced heating demands of the building. The heating system in the building was modified - the radiators were replaced with the new ones, the heating central unit was modernised. Moreover the local gas water heaters were eliminated. Then the building’s energy performance characteristics, prepared according to the valid Polish methodology, were compared with the real consumption. It was found that after the application of thermo-modifications the heating demand was reduced, twice. The economy efficiency of the thermo-modernisation was evaluated by means of a method of the annual costs. The annual costs include the heating system exploitation costs, DHW preparation system and the auxiliary devices electricity costs.
Temperature distribution analysis of different technologies of PV modules using infrared thermography
Authors: Gulkowski Slawomir , Zytkowska Natalia , Dragan Piotr
Published: August 2018

Photovoltaic systems are designed to operate for a very long time according to the modules’ warranty that guarantees at least of 80% of the nominal power production after 20 years of use. In order to assure the continuous power production with a high level for a long time, thermographic analysis should be performed to detect incipient anomalies in individual modules and junction boxes. This safe, convenient and noncontact method allows carrying out the inspection for working system without any contact with live wiring and without disconnecting the PV systems. Temperature distribution of the module surface can reveal many different types of anomalies, i.e. hot spots caused by local shading, microcracking or cell breakage. This paper shows the results of the infrared thermography analysis of the operating PV systems consisting of different technological modules: polycrystalline silicon (pc-Si), copper indium gallium diselenide (CIGS) and cadmium telluride (CdTe). The average working temperature of each different kind of technological module as well as overheated areas were investigated in this study. Temperature of the MC4 connectors was also analysed.
Application of an ultrasonic field for the removal of selected pesticides
Authors: Kida Małgorzata , Ziembowicz Sabina , Koszelnik Piotr
Published: August 2018

The work detailed in this study investigated the efficiency of oxidizing technologie for the removal of organochlorine pesticides (OCPs) from aqueous solutions. OCPs constitute an important group of environmental pollutants also known to be endocrine-disrupting compounds (EDCs). The particular focus has been on a process achieving oxidation through the use of ultrasonic waves, with the impacts of pH, time on TOC and pesticide removal all being tested. Results confirm effective TOC decomposition using ultrasonic waves, albeit with reaction time showing a significant impact on results. Furthermore, results for TOC were not found to reflect those relating to the removal of individual substances from the tested mixture. Chromatographic analysis of reaction mixtures was therefore carried out after the selected processes had been applied, and an attempt to identify and characterize degradation products of the pesticides tested was also made. During the irradiation, the H2O2 concentration arising was also monitored. The results indicate that H2O2 is produced by cavitation during ultrasonic irradiation.
Analytical meanders of selected systems for thermo-renovation of historical buildings
Authors: Ksit Barbara , Gaczek Mariusz
Published: August 2018

The article contains an analysis of selected systems for thermorenovation of vertical partitions in protected buildings. Historical buildings often require thermo-renovation, but in practice their "insulation" can be applied only internally on partitions without decorations. Internal thermorenovation methods can be classified according to heat exchange and moisture transport. For the purpose of this paper, the methods were analysed in terms of diffusion-open and diffusion-closed systems, and compared in a multi-variant aspect. The calculations were made assuming a wall with the moisture content up to 3%, a wall with the very high moisture content up to 11%, and for a wet wall with a constant inflow of water due to capillary action. They attempted to evaluate the effectiveness of various thermo-modernisation treatments in building partitions in the aspect of protection against permanent moisture growth, mould development and improvement of their overall heat protection, considering the 8-year time interval. Several different sets of materials were included in a multivariate analysis, as well as various scenarios of the possible effects of their use. The paper is summarised with conclusions regarding the effectiveness and risk related to the application of different internal methods of thermo-renovation of partitions.
A luminaire with variable light distribution
Authors: Leśko Marcin , Różowicz Antoni , Baran Krzysztof , Wachta Henryk
Published: August 2018

Industrial facilities such as production and storage halls are a specific environment, which is usually characterized by a large usable area, which is managed in a way that brings together in the given area many functional zones for various purposes. Frequent changes in the management of industrial halls gives a need to change the lighting method. In such a situation, a lighting solution that enables the photometric characteristics of the luminaires to be adapted to variable development of the facility, covering not only the quantitative regulation of the luminous flux, but also the direction of its radiation into the environment, can be a helpful solution. The article presents an innovative concept of a luminaire, which makes it possible to change the light distribution without the need to replace optical elements. Simulation tests were carried out for the developed luminaire in order to check the possibility of obtaining the assumed distribution and shapes of light spots on the working plane. Thanks to the application of this solution in an environment where there is a need for frequent changes in the development of usable space requiring changes in lighting conditions, it is possible to dynamically adjust the characteristics of the installed system to new environmental conditions.
The influence of the distribution of sound absorbing materials on the estimation of reverberation time in rooms
Authors: Olechowska Marcelina , Nowoświat Artur , Ślusarek Jan , Latawiec Mateusz
Published: August 2018

Reverberation time in rooms depends on many factors, e.g. cubature, surface of envelopes, sound absorption coefficient of materials used for the construction of the envelopes, geometry of rooms or the distribution of sound absorbing materials. The arrangement of sound absorbing materials in rooms has an impact on the dispersion of acoustic field, yet theoretical calculation models do not take into account this impact. According to these models, regardless of the arrangement of sound absorbing materials, the reverberation time in a room will remain unchanged. The present paper investigates the above problem by means of computer simulations. For the needs of the simulation, three rooms with different dimensions were adopted, i.e. type 'p' - a cuboidal room with a square base, type 'd' - a cuboidal room (with one side of the 'p' room lengthened), type 'w' - a cuboidal room (with the height of the room lengthened 'p'). During the simulation, the way of acoustic field dispersion was being changed and its influence on the reverberation time in the rooms was being determined. The authors investigated two situations. The first one involved a non-dampened room, in which the sound absorbing material was being arranged differently. The second one involved a welldampened room, and the dispersion of sound field was analyzed depending on the location of the reflecting material.
Sustainable cement mortars
Authors: Rucińska Teresa
Published: August 2018

The results described here on the basic technical parameters of cement mortars made from fine-grained concrete recyclate, ceramic recyclate, and slag, obtained from the incineration of municipal sewage sludge, demonstrate their usefulness in the production of building materials. Changes were introduced to the composition of cement mortars involving the replacement of natural aggregate with recyclate of the same fraction in the following volumes: 10%, 20% and 30%. The physicomechanical characteristics constitute the basis for further research which will help determine their practical applications.
Eye trackers in evaluation of transformation of historical monuments. Revitalisation of the Dresden arsenal
Authors: Rusnak Marta , Szewczyk Joanna
Published: August 2018

The paper concentrates on the application of an eye tracker as a tool used to evaluate the successfulness of transformations of various historic monuments for modern purposes. An eye tracker as a device capable of registering the path of one’s gaze makes it possible to analyze the way in which people perceive a given architectural object - in the case of this paper it is the former Dresden Arsenal, now known as the Bundeswehr Military History Museum. Since Daniel Libeskind, the architect behind the transformation, clearly defined the impression he what to achieve and the building provokes significant controversies, it was decided that it would be a suitable object for such a study. The survey was meant to find out whether the changes introduced by Libeskind actually helped him achieve the intended goal. The participants of the survey were shown images of the Arsenal’s façade from before the transformation, after the transformation in the daytime and after the transformation, but at night, with the illumination turned on. The paper not only shows and analyzes differences in the way people perceive these three images, but also raises a question as to the potential of eye trackers as tools used in architectural research.
Environmental aspects of energy supply of buildings in Poland
Authors: Sekret Robert
Published: August 2018

The article presents the assessment of the environmental impact of 9 variants of building heat supply for heating purposes. The building energy standards and the main primary energy carriers being in use in Poland were taken as input data. The subject of analysis was a single-family house characterized by a utility energy demand of 47 kWh/(m2 year). An environmental impact analysis was made using the specification for LCA in damage categories encompassing human health, ecosystem quality and natural resources depletion. From the obtained results it has been found that coal-based technologies in Poland's building energy supply systems are capable of reducing the noxious environmental impact. An example of such a system is the effective heat distribution network with a coal-based cogeneration energy source. From the point of view of radical low emission reduction, an interesting solution is the effective heat distribution network with a gas-based cogeneration energy source. Nevertheless, forecasts about the development of renewable energy source installations in Poland indicate that a significant role in building heat supply systems will be played by solar systems and geothermal systems using heat pumps. Achieving the environmental acceptance of heat pumps in Poland's conditions requires a decisive intensification of efforts to increase the share of renewable energy sources in electric energy generation processes in the central electric power system and in local and individual systems, as well as the continuation of the processes of thermal insulation of already existing buildings.
Data as a research infrastructure CDS, the Virtual Observatory, astronomy, and beyond
Authors: Genova Françoise
Published: August 2018

The situation of data sharing in astronomy is positioned in the current general context of a political push towards, and rapid development of, scientific data sharing. Data is already one of the major infrastructures of astronomy, thanks to the data and service providers and to the International Virtual Observatory Alliance (IVOA). Other disciplines are moving on in the same direction. International organisations, in particular the Research Data Alliance (RDA), are developing building blocks and bridges to enable scientific data sharing across borders. The liaisons between RDA and astronomy, and RDA activities relevant to the librarian community, are discussed.
Astronomy in Chile: Assessment of scientific productivity through a bibliometric analysis
Authors: Cortes Rodrigo , Depoortere Denise , Malaver Lucina
Published: August 2018

The skies of Northern Chile are considered among the best in the world for astronomy due to their geographical, climatic and atmospheric conditions. In fact, during the last several decades, a great number of astronomical observatories have been built by space research institutions devoted to space research, turning Chile into one of the countries with the greatest astronomical observation capacity in the world. Consequently, it is relevant to explore and assess the development of astronomy in Chile during the last ten years (2005-2015), carrying out a bibliometric analysis to extract traditional metrics, complemented with alternative metrics, to identify the Chilean production and scientific contribution of research in this field of knowledge. The results from traditional metrics, based on the information obtained in the Web of Science (WoS) database analyzed through InCites for the Astronomy & Astrophysics category indicate a sustained increase of the scientific production for the discipline during the last ten years. In particular, the Normalized Citation Impact of organizations and institutions conducting research in Chile is above the worldwide average. On the other hand, the alternative metrics, including for instance, the altmetrics types presented by the SCOPUS database, reflect that the Chilean research impact is much lower in the context of social networks.
Managing Contributions to the Unified Astronomy Thesaurus
Authors: Frey Katie , Weissman Sarah , Kern Barbara , Lagerstrom Jill , Peek Josh , Accomazzi Alberto
Published: August 2018

The Unified Astronomy Thesaurus (UAT) project managers have long defined the UAT as "an open, interoperable, and community-supported thesaurus." How do we solicit the detailed, comprehensive, and consistent community feedback that is required to keep the UAT relevant? The Steering Committee for the UAT has developed a visual organizational tool that lets reviewers suggest new concepts and restructure the existing hierarchy. Researchers and librarians can use this "Sorting Tool" to submit contributions and feedback to the UAT. The UAT Curator adds feedback to the UAT’s GitHub Issues, which allows for tracking, searching, and referencing the suggestions. The UAT Curator implements the accepted suggestions, preparing to include them in a future release of the Unified Astronomy The saurus. This process of continual improvement ensures that the UAT project remains community supported.
Scientific Writing Studio: How publishers can help authors to write smarter and faster
Authors: Henri Agnes , Van Rooyen Charlotte
Published: August 2018

Researchers are under pressure: publish or perish is one of their main challenges. Writing is hard and scientific writing is harder, and any help Publishers can provide to assist with the process is greatly appreciated, especially by younger authors. EDP Sciences and Astronomy & Astrophysics (A&A) have worked together to support their authors and developed a solution called Scientific Writing Studio (SWS) designed to make the article writing process easier. SWS is a tool that allows authors to collaboratively write their paper, then submit and then follow all stages of the publication process within a single unique interface. This paper explains the background to the development of the SWS, and describes the current benefits of the SWS as well as outlining future developments.
The NOAO Publications Tracking Program: Developing Policies & Procedures for Usage, Acknowledgment, and Citation of Data
Authors: Hunt Sharon , Norman Dara J.
Published: August 2018

The National Optical Astronomy Observatory (NOAO) has a complex publications tracking program, which is coordinated by the NOAO Librarian. We track publications that use data from multiple observatories (Kitt Peak National Observatory [KPNO] in Tucson, Arizona, and Cerro Tololo Inter-American Observatory [CTIO] in La Serena, Chile, as well as non-NOAO telescopes to which we grant community access at other observatories); multiple telescopes and instruments; multiple observing programs, including survey programs; and multiple datasets in the Science Data Archive (SDA) at NOAO. The growing SDA and new user services, such as the Data Lab, ensure that the use of NOAO archival datasets will become even more widespread and important for scientific discovery and research. Accurate and complete publication tracking is essential for reporting to our funding agencies, developing our programs, and determining our scientific contributions and impact. Setting policies to guide authors in specifying and acknowledging usage of NOAO data is an essential element in our ability to determine and document relevant publications. Developing systems to track the use of our telescope data and archival datasets is another critical element. New policies to track the use of our telescope data are being developed, new systems to track the use and reuse of datasets within our particular institutional context are being explored, and methods of linking our publications data with our dataset usage data are being devised. Updated policies for the proper and ethical usage, acknowledgement, and citation of our archival data are being written and reviewed.
The Effect of Injury Definition and Surveillance Methodology on Measures of Injury Occurrence and Burden in Elite Volleyball
Authors: MacDonald Kerry , Palacios-Derflingher Luz Maria , Emery Carolyn , Meeuwisse Willem
Published: August 2018

A time-loss injury definition continues to be the most widely used injury definition despite evidence that it fails to accurately capture overuse injuries. An overuse injury questionnaire, using an “all complaints” definition has been created to address the limitation of a time-loss definition. The main aim of this work was to determine the effect that injury definition and registration methodology has on the collection of knee injuries among elite level volleyball players. To reach this goal, seventy-two volleyball players were prospectively followed over 32-weeks. Time-loss injuries were captured using an individual injury report form (IIRF). Study participants completed an overuse injury questionnaire (mOIQ) via a weekly short message service (SMS). The IIRF captured 15 time-loss knee injuries in 72 study participants (20%). Based on the mOIQ, 84.7% of participants reported having a knee problem and 66.7% sustained a substantial knee problem. All IIRF knee injuries captured were also registered by the mOIQ. Agreement on the specific diagnosis occurred for 66.7% of injuries resulting in a moderate Kappa score of 0.51. In conclusion, an overuse injury questionnaire provided a greater understanding of the magnitude and burden of knee injuries in this population.
Colorectal MALT lymphoma: a rare clinical entity
Authors: Fischbach Wolfgang
Published: August 2018

Background Data on colorectal lymphoma in general and on MALT (mucosa-associated-lymphoid tissue) lymphoma, in particular are, very rare. There are no existing recommendations from current guidelines for how to manage these patients. We here report our experience from a clinical series.

Aim The aim of this study is to present clinical features and the endoscopic appearance of colorectal MALT lymphoma and therapeutic approaches.

Methods Seven patients (5 male and 2 female, aged 47 – 75 years) were diagnosed to have colorectal MALT lymphoma. All patients underwent a full staging work-up. A concurrent gastric MALT lymphoma was present in 2 patients. Follow-up was 37 (0 – 53) months.

Results Colorectal MALT lymphoma was diagnosed by screening or staging colonoscopy in 3 and 1 patient, revealing no clinical symptoms, respectively. Two patients complained about fatigue, obstipation, and a change in bowel habits. The endoscopic appearance of the MALT lymphoma comprised obstructive tumors (n = 2), polyps (n = 3), a flat lesion (n = 1), and vascular angiectasia (n = 1). In 6 cases, colorectal MALT lymphoma presented as a solitary lesion. Following endoscopic polypectomy, surgical resection, Helicobacter pylori eradication therapy, or systemic immune-chemotherapy, complete remission of lymphoma was achieved in 5 cases, while the outcome is unknown or cannot yet be estimated in 2 cases.

Conclusion A treatment and management approach based on the clinical and local presentation of the lymphoma and its involvement is proposed.
Endoscopic retrograde appendicitis techniques for the treatment of patients with acute appendicitis
Authors: Ye Li-Ping , Mao Xin-Li , Yang Hai , He Bi-Li , Zhu Lin-Hong , Zhang Yu
Published: August 2018

Objective The purpose of this study was to demonstrate the feasibility of endoscopic retrograde appendicitis therapy (ERAT) in treating patients with acute appendicitis.

Materials and methods Between January 2014 and December 2014, 22 patients with acute appendicitis underwent ERAT. Patient demographics, colonoscopy findings, endoscopic retrograde appendiceal radiography (ERAR) findings, and treatment outcomes of the ERAT and adverse events associated with ERAT were analyzed.

Results In this study, 22 patients with acute appendicitis underwent ERAT. The median age of the patients was 39.5 years. Colonoscopy findings included mucosal hyperemia and swelling of the appendiceal orifice and/or its surrounding mucosa (86.4 %, 19/22) and pus at the appendiceal orifice (40.9 %, 9/22). ERAR findings included irregular contour (76.2 %, 16/21), appendiceal lumen dilation (28.6 %, 6/21), appendiceal lumen stenosis (42.9 %, 9/21), and filling defect of the appendiceal lumen (23.8 %, 5/21). Deep intubation was successfully performed in 21 of the 22 patients (95.5 %). Sixteen patients underwent endoscopic appendiceal stent placement after endoscopic appendiceal irrigation (EAI) due to lumen stenosis of the appendiceal, excessive pus, or appendiceal fecalith, and the remaining 6 patients only underwent EAI. Among the 22 patients who underwent ERAT, their abdominal pain was noticeably relieved following the procedure. The main adverse events associated with ERAT were spontaneous discharge of the stent, recurrent abdominal pain, and recurrent appendicitis. During the follow-up (median 33 months), 2 patients underwent laparoscopic appendectomy.

Conclusions ERAT provide a new alternative therapeutic method for patients with acute appendicitis, particularly for certain patients who are unwilling to undergo an appendectomy.
The Role of Brain Connectome Imaging in the Estimation of Depressive Relapse Risk
Authors: Brandl Felix , Meng Chun , Zimmer Claus , Sorg Christian
Published: August 2018

Background About two-thirds of all patients with major depressive disorder (MDD) suffer from depressive relapse, the mechanisms of which are still poorly understood. In recent years, analyses of the brain’s connectome have increasingly been employed to identify potential biomarkers of depressive relapse. The term “connectome” refers to the map of all structural or functional connections in the brain. It can be investigated by structural or functional magnetic resonance imaging followed by graph theory-based analysis to characterize network topology on the global and regional level.

Methods This review is based on a selective literature search in PubMed representing the current state of research, as well as on an already published study which was awarded the Promotionspreis of the Deutsche Röntgengesellschaft.

Results and Conclusion Numerous studies point to altered network topology, e. g., of default-mode network and striatum, as being crucial for the pathophysiology of MDD. Our group was able to show that striatal centrality (or hubness) is associated with the number of depressive episodes, which is one of the best predictors for depressive relapse. These data suggest aberrant striatal network topology as a potential biomarker for depressive relapse risk. The translation of these promising findings into clinical routine diagnostics is promoted by several methodological advantages, while some unresolved issues still hinder this process.

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Structured Reporting in Clinical Routine
Authors: Pinto dos Santos Daniel , Hempel Johann-Martin , Mildenberger Peter , Klöckner Roman , Persigehl Thorsten
Published: August 2018

Background The radiology report is the key component in the communication between radiologists and referring clinicians. Traditionally, reports are written as free text. Several studies have shown that structured reporting using dedicated report templates has a number of advantages compared to conventional reports. Therefore, many radiological societies have recommended the implementation of structured reporting in clinical routine.

Method In the meantime, collections of freely available templates have been presented and software solutions for structured reporting have been made commercially available. These allow for quality improvements in the written radiology report as they ensure that all relevant clinical information is included. Most vendors mainly supply proprietary report templates or allow users to create templates for their own institution. The German Radiological Society (DRG) has the goal of developing consensus-based, quality-assured report templates and providing them under a free license.

Results The DRG has developed its first consensus-based report templates and provides them at www.befundung.drg.de. Further report templates will be developed in close cooperation with the respective committees of the DRG and referring clinicians.

Conclusion Structured reporting allows for a significant improvement in the quality of written radiology reports. The use of report templates requires personal and technical changes to the reporting process itself. Radiology should face these challenges in its leading role in the application of modern IT-based solutions. Vendors are now encouraged to provide practical solutions.

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