bluuebunny/crossref_metadata_2025 huggingface dataset:
Presentación
Authors: Cordera  Campos Rolando , Cárdenas Solórzano Cuauhtémoc
Published: September 2024

Los documentos que aquí se presentan son un referente del trabajo sistemático del GNCD; el lector encontrará un ejercicio de análisis y elaboración de recomendaciones para el diseño de una estrategia nacional de desarrollo sostenible, equitativo e igualitario, ambiental y territorialmente sustentable. Esta aportación se suma a las que en años previos ha generado el GNCDpara contribuir a la reflexión y el debate público. En el año 2019 se presentó el texto “Consideraciones y propuestas sobre la estrategia de desarrollo para México”, y entre 2020 y 2022 se ofrecieron planteamientos para renovar y orientar las políticas hacia un nuevo curso de desarrollo.
Energía para el desarrollo
Authors: Eibenschutz  Hartman Juan , Muñoz Villalobos José Manuel , Osorio  Romero Sergio Benito , Ruiz Alarcón Fluvio , Torres Flores Ramón Carlos , Villalobos Hiriart Alejandro
Published: September 2024

El Estado mexicano tiene la responsabilidad constitucional de garantizar la disponibilidad de energía para todos y, al mismo tiempo, de reducir las emisiones atmosféricas de carbono. Carece sin embargo de una estrategia institucional con legitimidad democrática y visión de largo plazo que facilite el cumplimiento de esa responsabilidad. El presente texto pretende contribuir al debate nacional en el camino de construir esa estrategia. Se analizan vías potenciales de transformar el sistema energético--teniendo en cuenta el entorno externo y las tendencias de la transición mundial-- y se formula un conjunto de propuestas de reformas al orden jurídico e institucional que rige las actividades relacionadas con el uso y la transformación de la energía para el desarrollo.
Arduino-Powered Remote Monitoring System for Real-Time Heart Rate Detection via Bluetooth
Authors: Kamati Veer Chandra
Published: September 2024

With the increasing need for continuous health monitoring, this study presents the development of an Arduinopowered remote monitoring system for real-time heart rate detection via Bluetooth. The system uses an Arduino microcontroller connected to a pulse sensor to measure heart rate, with data wirelessly transmitted via Bluetooth to a remote device, enabling continuous monitoring without direct patient interaction. Initial self-monitoring trials showed consistent heart rate detection within the normal range of 62-70 beats per minute (BPM), suggesting proper functionality for preliminary use. The system also maintained a stable Bluetooth connection with no noticeable data loss. This cost-effective and efficient system is a valuable tool for telemedicine and remote patient care. Future enhancements may include integrating advanced microcontrollers and developing a more sophisticated mobile app with expanded health monitoring features.
Vivencias del profesional de enfermería en el cuidado humanizado a personas con diversidad de género
Authors: Ramírez Moreno Paola , Santelices Tello Cecilia , Correa Quiroz Andrea , Silva Morales Bárbara , Venegas Rojas Bárbara
Published: September 2024

Introducción: La atención en salud de los profesionales de enfermería a personas con diversidad de género puede verse afectada negativamente por la heteronormatividad que ha regido históricamente la sociedad. Actualmente es un desafío resguardar y buscar acciones para entregar un cuidado humanizado inclusivo. Objetivo: Comprender las vivencias del profesional de enfermería al brindar el cuidado humanizado a personas con diversidad de género. Método: Investigación cualitativa, con un enfoque fenomenológico. Se entrevistó a cuatro profesionales de enfermería. La información se recopiló a través de entrevistas individuales y grupales semiestructuradas; los discursos fueron analizados y se realizó una triangulación de los conceptos principales. Resultados: El cuidado humanizado se manifiesta a través de tres dimensiones: vivencias al brindar cuidados humanizados, factores que facilitan la entrega del cuidado humanizado y factores que lo dificultan. Las categorías incluidas en la primera dimensión son igualdad, empatía, respeto y aprendizaje. Los factores que facilitan los cuidados humanizados tienen como categorías la acogida y la formación continua, y los factores que lo dificultan tienen las categorías de nombre social y recelo. Conclusión: El cuidado humanizado a personas con diversidad de género requiere valores de igualdad y empatía, junto con una formación inclusiva desde pregrado. La deficiencia en el desarrollo de habilidades blandas dificulta la relación enfermero-paciente, mientras que el recelo de la persona con diversidad de género obstaculiza las primeras consultas. La integración del nombre social y la formación continua son esenciales para promover un ambiente de confianza y reducir la sensación de vulnerabilidad y discriminación.
Perfect quantum protractors
Authors: Piotrak Michał , Kopciuch Marek , Fard Arash Dezhang , Smolis Magdalena , Pustelny Szymon , Korzekwa Kamil
Published: September 2024

In this paper we introduce and investigate the concept of a perfect quantum protractor, a pure quantum state |ψ⟩∈H that generates three different orthogonal bases of H under rotations around each of the three perpendicular axes. Such states can be understood as pure states of maximal uncertainty with regards to the three components of the angular momentum operator, as we prove that they maximise various entropic and variance-based measures of such uncertainty. We argue that perfect quantum protractors can only exist for systems with a well-defined total angular momentum j, and we prove that they do not exist for j∈{1/2,2,5/2}, but they do exist for j∈{1,3/2,3} (with numerical evidence for their existence when j=7/2). We also explain that perfect quantum protractors form an optimal resource for a metrological task of estimating the angle of rotation around (or the strength of magnetic field along) one of the three perpendicular axes, when the axis is not a priori known. Finally, we demonstrate this metrological utility by performing an experiment with warm atomic vapours of rubidium-87, where we prepare a perfect quantum protractor for a spin-1 system, let it precess around x, y or z axis, and then employ it to optimally estimate the rotation angle.
Pelaksanaan Penyusutan Arsip di Fakultas Ilmu Sosial dan Politik Universitas Padjadjaran
Authors: Adna Putri Latifa , Sukaesih Sukaesih , Sujana Lusi Romaddyniah
Published: September 2024

Penelitian ini bertujuan untuk mengetahui dan mendeskripsikan secara mendalam mengenai penyusutan arsip yang dilakukan di Record Center Fakultas Ilmu Sosial dan Politik Universitas Padjadjaran. Penelitian ini menggunakan metode penelitian kualitatif dengan pendekatan studi kasus. Objek penelitian pada penelitian ini adalah seorang informan yang menjabat sebagai staf arsiparis di Record Center Fakultas Ilmu Sosial dan Politik Universitas Padjadjaran dengan menggunakan purposive sampling untuk memilih informan. Jenis data yang digunakan adalah data deskriptif. Teknik pengumpulan data pada penelitian ini dilakukan melalui tiga cara, yaitu observasi, wawancara, dan studi pustaka. Sementara itu, analisis data yang diterapkan pada penelitian di antaranya adalah reduksi data, penyajian data, penarikan kesimpulan, dan verifikasi. Untuk menguji keabsahan data, peneliti menggunakan teknik triangulasi sumber dengan cara membandingkan hasil pengamatan dengan hasil wawancara dan menguji kebenaran keduanya dengan dokumen yang mendukung. Berdasarkan hasil penelitian, didapatkan bahwa kegiatan penyusutan arsip di Record Center Fakultas Ilmu Sosial dan Ilmu Politik Universitas Padjadjaran dilaksanakan melalui tiga tahap, yaitu tahap pemindahan, tahap penyerahan, dan tahap pemusnahan dengan berpedoman pada Peraturan Rektor Universitas Padjadjaran.
THE DEVELOPMENT OF STUDENT WORKSHEETS (LKPD) WITH A SCIENTIFIC APPROACH ON THE MATERIAL OF AKIDAH AKHLAK AT THE CLASS VIII OF MADRASAH TSANAWIYAH
Authors: Ansari Muhammad , Budiman Zulfatmi , Nurdin Realita , Basri Hasan , Nisak Qudwatin
Published: September 2024

The purpose of this study was to create a scientific-based Student Worksheets (LKPD) on the subject matter of Akidah Akhlak grade 8 Madrasah Tsanawiyah by knowing the level of feasibility and the teacher's response to the product being developed. This study uses research and development methods with the ADDIE model, including five steps: Analysis, Design, Development, Implementation, and Evaluation which are modified according to the conditions at the time of the study. Data collection techniques used validation sheets and teacher response questionnaires. The percentage of the LKPD feasibility validation stage is from the material field, it gets 98.8%, the media field gets 90%, the language field gets 75%, and the scientific approach field gets 98.3%. The total average value of the overall percentage of validators is 90.5% with the criteria of Very Eligible. While the results of the questionnaire responses to Akidah Akhlak teachers obtained a total percentage of 88.4% with very good criteria for the scientific-based Akidah Akhlak LKPD product. So, it can be concluded that this scientific-based LKPD can be used as teaching material in the learning process in the classroom.
DEVELOPMENT OF THEMATIC HANDOUT MATERIALS BASED ON THE LOCAL WISDOM OF NUTMEG FOR LEARNING
Authors: Raharti Nelli , Jarmita Nida , Hayati Zikra , Ramadhani Desi
Published: September 2024

Their perception causes a lack of student interest in learning through printed teaching materials that local wisdom presented in textbooks is not relevant to the local knowledge of their region. In addition, most teachers do not utilize locally-based teaching materials, reducing student involvement in the learning process. This study aimed to develop and assess the feasibility of thematic teaching materials based on local wisdom, evaluate the feasibility of the teaching materials, and Assess teacher responses to the teaching materials. The research method used was Research and Development (R&D) using the ADDIE model, including the stages of analysis, design, development, implementation, and evaluation. During the analysis phase, a needs assessment was carried out to ensure the relevance of local wisdom, especially regarding the material on nutmeg, in the teaching materials. The study subjects were grade IV students of MIN 2 South Aceh. The research instruments included a validation questionnaire from media and material experts and a response questionnaire from teachers and students. The validation results showed that local wisdom-based teaching materials about nutmeg and its benefits were considered feasible, with a score of 75% from media experts and 73% from material experts, categorized as "feasible." Students' responses to the teaching materials showed that the materials were very interesting, with a score of 94.5%, while teachers' responses reached 72%, categorized as "interesting." The implications of this study indicate that the development of locally based teaching materials can significantly increase students' interest and involvement in learning and provide practical guidance for teachers in utilizing materials relevant to the local context.
NOVEL LEAF MACERATION TOOL FOR LABORATORY PROCEDURES
Authors: Rocha-Sobrinho Geraldo Gomes , Santos Mesquita Naasoom Luiz , Silva de Novaes Quelmo , Leitão Carlos André Espolador
Published: September 2024

A maceração de folhas é utilizada em vários protocolos laboratoriais. O método mais comum é realizado com almofariz e pistilo. Essas ferramentas são milenares e executam satisfatoriamente o procedimento de maceração, embora seja trabalhoso e cansativo. O presente trabalho apresenta uma ferramenta e um método inovador para maceração foliar. Para esse fim, foi construído um macerador metálico, constituído por um cabo, um eixo, rolamentos e arruelas, que funciona como um mini rolo compressor. O processo de maceração consiste em rolar o macerador sobre um saco plástico contendo a amostra de folha e a solução extratora, apoiado sobre um pano. Para testar o equipamento, foram realizadas macerações em folhas de maracujazeiro com o método aqui proposto em comparação com o método tradicional, utilizando almofariz com pistilo. O tempo de maceração com o novo macerador foi em média 42,98% menor que o método tradicional, com almofariz e pistilo. Além disso, o processo de maceração é menos trabalhoso e permite a maceração de um maior número de amostras sem risco de contaminação.
Comparative Analysis of Cooling Load Calculations: CLTD Method vs. Carrier HAP 5.01 Software for Hotel HVAC Design
Authors: Prawibowo Madarif , Komarudin Komarudin
Published: September 2024

This study examines the cooling load requirements of a hotel building by comparing two methodologies: the traditional Cooling Load Temperature Difference (CLTD) method and the Carrier Hourly Analysis Program (HAP) 5.01 software. The primary objective is to validate the accuracy and reliability of these methods in calculating cooling loads across different room types, from standard rooms to larger, more complex suites. The results show that the CLTD method consistently yields higher cooling load estimates, with discrepancies ranging from 3% to 14% compared to HAP 5.01 calculations. These differences are most significant in larger rooms, such as suites and owner’s suites, which have more extensive glass areas, higher occupancy, and more heat-generating equipment. The findings indicate that while the CLTD method is valuable for quick, preliminary estimates, the HAP 5.01 software provides a more precise and comprehensive analysis, taking into account hourly variations, equipment schedules, and other factors that impact cooling loads. This research highlights the need for careful selection of the appropriate calculation method to ensure the efficient design of HVAC systems, maximizing energy efficiency, and maintaining occupant comfort. The study concludes that for projects requiring high accuracy, particularly in complex or large spaces, dynamic simulation tools like HAP 5.01 are preferable. Detailed cooling load results and comparisons are provided in the supplementary documentation, offering further insights into the analysis and its implications for HVAC design.
Effect of Pouring Temperature Variation on Cooling Rate, Hardness and Microstructure of Al-Zn in Aircraft Structures
Authors: Pambekti Arif , Prakoso Agung , Dinaryanto Okto , Rahmandhika Andinusa , Yaqin Rizqi Ilmal
Published: September 2024

Al-Zn alloys are widely utilized in industries such as automotive, aircraft manufacturing, and advanced military equipment due to their exceptional strength-to-weight ratio. Among various fabrication methods, metal casting is a commonly used technique for producing structural components from these alloys. However, a significant challenge with metal casting is the reduction in mechanical properties compared to the base material before melting. This reduction highlights the need for research to identify the optimal casting conditions, particularly the casting temperature, which plays a crucial role in maintaining and potentially enhancing the material's mechanical properties. Aluminum alloy 7075, known for its high strength, was selected for investigation. According to the Al-Zn phase diagram, the melting point of aluminum alloy 7075, based on the weight percentage specified by the Standard Aluminum Association, is approximately 660°C. Experiments were conducted by varying the pouring temperature during casting in 30°C increments above this melting point. Specifically, the alloy was melted and cast at three different temperatures: 690°C, 720°C, and 750°C. The mold temperature was consistently maintained at 220°C to isolate the effects of the pouring temperature. Results indicate that increasing the casting temperature significantly affects the alloy's microstructure and mechanical properties. As the casting temperature increases, the cooling rate decreases, leading to a finer grain structure. This finer grain size directly contributes to an increase in hardness, suggesting that higher casting temperatures can enhance the mechanical properties of Al-Zn alloys. These findings emphasize the importance of precise control over casting temperatures to optimize the performance characteristics of aluminum alloy 7075 in high-strength applications.
In Silico Analysis of the Association of Damage Suppressor (Dsup) Proteins of Tardigrades with BRCA1 Protein of Homo sapiens
Authors: Arquero Aron Joshua B. , Yango Hazel Eunice F.
Published: September 2024

Proteins are vital molecules for biological processes—for regulation
and structure. Notably, proteins are prone to degradation due to
environmental factors like radiation. Radiation elicits reactive oxygen
species (ROS) that accumulate as oxidative stress. Hence, it is
suggested that the damage suppressor (Dsup) protein, the protein
responsible for the extremotolerant ability of tardigrades should be
utilized as a therapeutic agent for protection and cell longevity. One
of the recommended targets is the BRCA1 protein, which functions for
tumor suppression and is susceptible to degradation. Using AlphaFold for
protein modeling, HADDOCK and PRODIGY for protein-protein docking and
scoring, and STRING to establish a protein-protein interaction network
to screen relative proteins of BRCA1 that can be docked with Dsup and
possibly affected pathways and functions because of the interaction. The
researchers generated a complex model of the Dsup protein of
Ramazzottius varieornatus and the Dsup-like protein of
Hypsibius exemplaris with the BRCA1 protein of Homo
sapiens. The potential optimal binding site of the Dsup on the BRCA1 is
a semi-flexible region. The PPI network was established, and ATR, ATM,
RAD50, RAD51, MSH2, MYC, and RB1 were suggested for future docking
studies with Dsup. The probable affected pathway is organ system cancer
and the BRCA1-DNA and BRCA1-Nucleic acid-dependent function. In
conclusion, the Dsup and BRCA1 association is possible. These findings
contribute to the potential application of Dsup to medicine and human
space endeavors. However, further investigation of extensive molecular
dynamics analysis and experimental validation such as in vivo and
in vitro is recommended.
The maternity care experiences of women living in a diverse UK urban city: a survey study.
Authors: Watson Kylie , Barber Charlotte , Farrant Kimberley , McEvoy Bethan , Mills Tracey , Lavender Dame Tina
Published: September 2024

Objective To understand the maternity experiences of women
living in areas of high ethnic diversity and social deprivation.
Design An anonymous self-reported on-line survey incorporating
demographic, clinical outcome and validated tool (Experience of
Maternity Care) questions, and free text responses. Setting A
large urban NHS Trust in Northwest England Sample Postnatal
women, living in eight postcodes identified as areas of high
socio-economic deprivation and ethnic diversity. Methods
Quantitative data was collected and analysed using appropriate
statistics. Free text responses were coded and thematically analysed.
Main outcome measures Experience of Maternity Care scores and
free text themes. Results Sixty-four percent of the sample
identified as from an ethnic minority. Black women (42/68, 62%) were
more likely (p=0.003) to attend their first antenatal visit at 12 or
more weeks’ gestation compared to White (69/87, 79%) or Asian women
(127/150, 85%). Black (p=0.004) and multiparous (p=0.012) women were
more likely to report a positive postnatal experience. Most women were
positive about the care they received overall, but responses to specific
questions revealed concerns related to some aspects. Most (82%)
respondents did not mind being looked after during labour and birth by
midwives or doctors they had not met before. Themes from free text
responses included continuity of care, respectful care, communication,
early labour care and access to timely pain relief. Conclusions
Using a targeted approach ensured an ethnically diverse sample and
despite overall positive experiences of maternity care, negative
experiences reflect similar themes previously identified within UK
maternity care.
On behaviours for the solution to a certain third-order stochastic integro-differential equation with time delay
Authors: Mahmoud A.M. , Bakhit D.A.M.
Published: September 2024

In the present paper, Lyapunov functional (LF) is employed to discuss the
continuability and boundedness of solutions for a third-order non-autonomous
stochastic integro-differential equation (SIDE) with time delay. The
third-order differential equation is ablated to a system of first-order
differential equations together with its equivalent quadratic function to
derive a suitable downright LF and then we study the behaviour of the
solutions. A numerical example is considered to support our results.
Moreover, we use the Euler-Maruyama method to get an approximate numerical
solution for the considered system. The obtained result complements some
recent ones in the literature.
Certain vector fields on f-Kenmotsu manifold with Schouten-van Kampen connection
Authors: Sah Vaishali , Yadav Sarvesh , Upreti Jaya
Published: September 2024

The present study investigates various characteristics of conformal Ricci
solitons with a Schouten-van Kampen connection. Characterizations are
obtained when the potential vector field involves a torse-forming vector
field. Moreover, applications related to submanifolds are also provided.
Lastly, we provided an example of conformal Ricci solitons on a
three-dimensional f-Kenmotsu manifold to validate our findings.
Almost *-Ricci solitons on contact strongly pseudo-convex integrable CR-manifolds
Authors: Aruna Kumara H. , Sikdar Karabi , Venkatesha V.
Published: September 2024

We prove that if contact strongly pseudo-convex integrable CR-manifold admits
a *-Ricci soliton where the soliton vector Z is contact, then the Reeb
vector field ? is an eigenvector of the Ricci operator at each point if and
only if ? is constant. Then we study contact strongly pseudo-convex
integrable CR-manifold such that 1 is a almost *-Ricci soliton with potential
vector field Z collinear with ?. To this end, we prove that if a
3-dimensional contact metric manifoldMwith Q? = ?Q which admits a gradient
almost *-Ricci soliton, then either M is flat or f is constant.
Pseudo generalized quasi-Einstein manifolds with applications to general relativity
Authors: Vasiulla Mohd , Ali Mohabbat
Published: September 2024

Quasi-Einstein manifold and generalized quasi-Einstein manifold are the
generalization of Einstein manifold. In the present paper we discuss about a
set of some geometric properties of pseudo generalized quasi-Einstein
manifold and we give three and four examples (both Riemannian and
Lorentzian) of pseudo generalized quasi-Einstein manifold to show the
existence of such manifold. We also discuss PG(QE)4 spacetime with
space-matter tensor and some properties related to it. Lastly we prove the
existence of a pseudo generalized quasi-Einstein spacetime by constructing a
non-trivial example.
Uniformly continuous extension in L-uniform convergence tower spaces
Authors: Jäger Gunther
Published: September 2024

Using an extension theorem for continuous mappings between quantale-valued
convergence tower spaces that we obtained in a previous paper, we prove an
extension theorem for uniformly continuous mappings between quantale-valued
uniform convergence spaces. To this end, we define and study suitable
uniform diagonal axioms and uniform regularity for quantale-valued uniform
convergence tower spaces.
Generalized solution of burger equation
Authors: Sadek Soukaina , Chadli Lalla , Moujahid Abdelaziz , Elomari M’hamed , Melliani Said
Published: September 2024

In this paper, The existence and uniqueness of the generalized solution of
the Burger equation is studied with initial conditions are distributions
(elements of Colombeau algebra). then we look at the association notion in
conjunction with the classic solution.
Relating the annihilation number and the 2-domination number for unicyclic graphs
Authors: Hua Xinying
Published: September 2024

The 2-domination number ?2(G) of a graph G is the minimum cardinality of a
set S ? V(G) such that every vertex from V(G)\S is adjacent to at least
two vertices in S. The annihilation number a(G) is the largest integer k
such that the sum of the first k terms of the non-decreasing degree sequence
of G is at most the number of its edges. It was conjectured that ?2(G) ?
a(G)+1 holds for every non-trivial connected graph G. The conjecture was
earlier confirmed for graphs of minimum degree 3, trees, block graphs and
some bipartite cacti. However, a class of cacti were found as counterexample
graphs recently by Yue et al. [9] to the above conjecture. In this paper, we
consider the above conjecture from the positive side and prove that this
conjecture holds for all unicyclic graphs.
On density topology using ideals in the space of reals
Authors: Banerjee Amar , Debnath Indrajit
Published: September 2024

In this paper we have introduced the notion of I-density topology in the
space of reals introducing the notions of upper I-density and lower
I-density where I is an ideal of subsets of the set of natural numbers. We
have further studied certain separation axioms of this topology.
Development workflow based on in situ synchrotron investigations to optimize laser processing of copper pins
Authors: Hummel Marc , Spurk Christoph , Heider Andreas , Beranek Matthias , Häusler André , Möller Mauritz , Beckmann Felix , Moosmann Julian
Published: September 2024

To design future laser manufacturing processes for welding of copper materials, more and more high-end analysis methods are required. A fundamental process understanding by analyzing cause-and-effect relations of process dynamics using inline in situ diagnostics allows for an improved description of laser material interaction. Strategies for a reliable and robust welding process are derived from the findings. In this study, a four-step advanced methodical approach is presented and discussed. In the first step, a fundamental process description of the geometry of the vapor capillary and the formation of weld defects is developed. Therefore, welds on electrolytic tough pitch copper (Cu-ETP) and CuSn6 are carried out to analyze the temporal and spatial vapor capillary dynamics depending on laser power, welding speed, and focal diameter. This fundamental process understanding is transferred to the welding of copper pins in the form of I-pins. For this purpose, impurities and imperfections were applied to the pin surface to investigate the effects on the process result. As a third step, strategies by means of laser intensity distributions were adapted to compensate for imperfections in the welding process. Finally, a sensor vision system is adapted for ideal welding results. Investigations are based on in situ synchrotron analysis at Petra III, DESY in Hamburg. For the experiments, a TRUMPF TruDisk laser (100/400 μm fiber diameter), a TRUMPF TruFiber 6000P (50/100 μm fiber diameter), and a single-mode fiber laser (14 μm fiber diameter) were used. The focal diameter was adjusted with the optical system depending on the investigation.
COMPOSITION OF VOLATILE BIOACTIVE COMPOUNDS OF SEA CUCUMBER (HOLOTHURIA ATRA) EXTRACT AND THEIR BIOACTIVITY AS ANTIVIRALS FOR SARS-COV-2 COVID-19
Authors: Nugroho Endik , Sururi Ahmad Misbakhus , Rahayu Dwi Anggorowati , Ardiansyah Reza , Kurniawan Nia , Widodo Widodo , Ainiyah Roisatul
Published: September 2024

COVID-19 is a pandemic that has an impact on all aspects of life. This pandemic is caused by the SARS-CoV-2 virus, which has a fast pathogenesis cycle, so alternatives are needed, such as incredibly natural and marine ingredients that can be used as drug candidates. Holothuria atra is an animal candidate that has great potential. This study aims to describe the potential of H. atra as an antiviral candidate for COVID-19 through in silico analysis. The research began with extracts and GC-MS tests to identify the compound content in H. atra. Molecular docking analysis, Lipinski druglikeness, and toxicity predictions were carried out to determine the potential of the compound as an antiviral candidate for COVID-19 through inhibition of RNA-dependent RNA-polymerase protein (RdRp) and human Angiotensin Converting Enzym-2 (hACE2). The research results showed that there were five volatile compounds in the methanol extract of H. atra with one potential compound as a COVID-19 antiviral, namely Cyclohexanone, 2,6-bis((4-methoxyphenyl)methylene)-. Lipinskis druglikeness analysis and toxicity prediction provide support as a COVID-19 antiviral. Further research, such as in vitro and in vivo testing, can be carried out to give an overview of living cells and its activity as an antiviral for COVID-19.
Alteration of Biochemical Parameters in Patients with Respiratory Acidosis and Alkalosis: A Hospital Based CrossSectional Study
Authors: LB* Sapkota , S Thapa , G Aryal , S Sharma , DB Saru
Published: September 2024

Biochemical parameters like pH, pO2, pCO2, HCO3-, TCO2 and SO2 are frequently measured in critically ill patients with respiratory acidosis and alkalosis. These parameters have utmost importance in the assessment of ventilation, oxygenation and acid base status of these patients. The present study was undertaken to determine alteration of different biochemical parameters in patients with respiratory acidosis and alkalosis. This is a hospital based cross-sectional study conducted from May to December 2023, in the Department of Biochemistry, CMCTH. Arterial blood was collected and biochemical parameters like pH, pO2, pCO2, HCO3-, TCO2 and SO2 were measured using automated blood gas analyzer. Statistical analysis was done with SPSS version 21. This study showed that majority of the patients with respiratory acid-base disorder were females (58.1%) and elderly (41.8%). Respiratory acidosis and alkalosis were more common in elderly patients under age group 61- 70 years followed by >70 years category. Respiratory acidosis was accompanied by alteration of various ABG parameters like low pH, low pO2, high pCO2, high HCO3-, normal TCO2 and normal SO2 levels while respiratory alkalosis was accompanied by high pH, low pCO2, low HCO3-, low TCO2, normal sO2 and normal pO2 levels. Respiratory acid-base disorders are common in hospital settings with ailing respiratory diseases like COPD, Pneumonia, TB and Sepsis with higher incidences among elderly patients. Respiratory acidosis and alkalosis should be treated promptly giving highest consideration to various biochemical parameters in order to reduce comorbidities and mortalities associated with these conditions.
internacionalização da educação do/no Instituto Federal Farroupilha
Authors: Rosa Tamara Angélica Brudna da , Ziegler Fernanda Lopes Silva , Arnt Janete Teresinha
Published: September 2024

Este artigo visa apresentar os documentos e as práticas referentes à internacionalização da educação do/no IFFar, de forma a problematizar como a criação de uma política linguística voltada para a internacionalização pode impactar as ações de internacionalização em todos os âmbitos educacionais da instituição. Como perspectiva teórica, apoiamo-nos nos pressupostos da Linguística Aplicada Sulear (Pennycook; Makoni, 2020) e dos estudos dos Letramentos Acadêmicos (Lea; Street, 1998, 2006). Os resultados desta pesquisa indicam que há interesse e/ou necessidade institucional em regular e organizar pautas relativas à internacionalização da educação e ao estabelecimento de uma política linguística. Contudo, em uma perspectiva abrangente de internacionalização, faz-se necessário refletir conscientemente e agir criticamente para que ações e, sobretudo, políticas sejam possam vir a contribuir efetivamente no IFFar e por meio do IFFar.
The Prevalence of Different Genotypic Forms of Familial Hypercholesterolemia in Relation to Race and Ethnicity
Authors: Bekbossynova Makhabbat , Ivanova-Razumova Tatyana , Kali Aknur , Sailybayeva Aliya , Khamitov Sadyk , Oralbekova Zhansaya
Published: September 2024

In the present study, a systematic literature review was conducted to examine the prevalence of homo- and heterozygous forms of Familial hypercholesterolemia among different racial and ethnic groups. Familial hypercholesterolemia (FH) is an inherited disorder characterised by elevated blood levels of cholesterol and low-density lipoprotein (LDL), which increases the risk of cardiovascular disease. Databases PubMed, Web of Science, and Elsiever were searched and only peer-reviewed articles with a large number of contributors and sufficient prevalence and ethnicity data were included. Diagnosis of FH was based on genetic testing or clinical criteria. The results of the study indicate inadequate and untimely diagnosis of FH, resulting in inadequate treatment. To date, only 9% of countries have statistical data on the prevalence of FH in the general population. In order to develop effective prevention strategies for cardiovascular diseases associated with FH, further research is needed to obtain accurate epidemiological data, including the race and ethnicity of patients. This will allow optimisation of strategies to reduce the burden of preventable cardiovascular disease associated with FH.

 
Disclosing adolescents' gynecological concerns: exploring trends in adolescent gynecology visits and complaints
Authors: Uyaniklar OO , Rahimli Ocakoglu S , Atak Z , Suer E
Published: September 2024

Adolescence represents a pivotal phase in the transition from childhood to adulthood. Adolescent gynecology is the clinical specialty that focuses on the management of gynecologic problems during this period. This study's primary objective is to emphasize the importance of adolescent gynecology by examining the gynecological causes of adolescent presentations and highlighting the differences that warrant consideration in the clinical approach to adolescent patients. The study was designed as a retrospective cohort study in an academic tertiary hospital and included adolescent individuals presenting to the obstetrics and gynecology emergency department or outpatient clinic. The analysis encompassed a range of factors, including age, presenting symptoms, examination findings, ultrasound results, laboratory data, and the necessity for hospital admission. The study cohort comprised 750 adolescent patients, 71.3% seeking gynecological care. Adolescents most frequently presented for menstrual irregularities (57.6%) and secondly for dysmenorrhea. The results of the gynecological clinical evaluations indicated that 62.9% of the patients had menstrual disorders. Of these, 53.4% had irregular menstrual cycles, 4.5% had prolonged and/or heavy bleeding, and 3% had amenorrhea. Ultrasound imaging revealed the presence of pathological findings in 25.8% of the patients. In conclusion, this study's findings indicate that irregular menstrual cycles are the most common gynecological condition in the adolescent population. The physiological characteristics of adolescents require a distinct approach to diagnosis and treatment compared to adult women, which can significantly impact future fertility and overall reproductive health.
Іncrease in the number of sentences for commitment of family violence as an indicator of increase in the level of legal culture of the society
Authors: Avramenko S. M. , Melnyk A. R. , Pantaliienko T. P.
Published: September 2024

The article highlights the issue of the increase in the number of cases of domestic violence known to law enforcement agencies. Factors affecting the increase of legal awareness of citizens and encouraging them to take decisive actions for zero tolerance to various types of violence in families are analyzed in detail.
We analyzed the changes in the legislation of Ukraine, which became the driving force for the fight against domestic violence, the protection of victims and the punishment of offenders. An important step for this was the introduction of amendments to the Criminal Code of Ukraine and the addition of Article 126-1 “Domestic violence”. At the same time, an important factor in the formation of public awareness of the inadmissibility of domestic violence is the activity of public organizations, public figures, the media community, and mass media.
The trend of increasing the level of legal culture of the individual in terms of zero tolerance for the actions of offenders is being followed. Society increasingly does not tolerate violence and strives for justice. It also shows that the legal culture of the individual is growing, people respect the law more and more and understand the importance of human rights.
The connection is investigated, according to which increasing the level of awareness of citizens about their rights and about the possibilities of protection against violence leads to an increase in the number of appeals to the police and restoration of their rights by legal means. It has been proven that people seek help more and more often, knowing that they have support from the state.
The number of sentences contained in the Unified State Register of Court Decisions for domestic violence in the period 2020–2024 is analyzed.
It has been studied that the increase in the number of sentences for committing domestic violence is directly proportional to the increase in the level of legal culture of the individual and society. This fact confirms the opinion, however, that domestic violence is gradually leaving the category of latent crimes and victims are no longer ready to put up with violence in families.
It was concluded that the development of legal culture in this context means that people not only know about the inadmissibility of violence, but also realize the importance of observing laws and actively participating in the fight against this problem.
Peculiarities of normative regulation training of specialists in security activities
Authors: Likhovitskyi J. O.
Published: September 2024

The article deals with the peculiarities of professional training normative regulation of security personnel. It was found that there is no scientific research on the normative regulation of the qualification requirements that are put forward to the security personnel. The aim of the research is to prepare proposals for improving the regulatory regulation of security specialists’ training. To achieve the goals of the article, a complex of scientific methods was used: formal and dogmatic one - during the analysis of the provisions of normative legal acts in the sphere of security activities; comparative legal method - within the limits of comparing the norms of legislative and by-laws. The application of the methods of analysis, synthesis, induction and deduction made it possible to build a logical structure of the scientific article and draw reasonable conclusions regarding the optimization of normative regulation of the educational training of security specialists.
The present research analyzed the history of legal regulation of security specialists’ training in Ukraine, identified shortcomings and gaps in the regulatory framework of this sphere of activity. It was established that the existing standards of higher education do not take into account the needs of subjects of security activities in the training of security personnel. It has been proven that the normative and legal framework in the sphere of security activities does not require specialists in organization of security measures to have a specialized higher education. It is justified that the bachelor’s degree holders (specialty «Personal and Property Security») and master’s degree holders (specialty «Security Activities and Safety») should not have different specializations.
It was concluded that the differences can only be in the focus of the training specialties of bachelor’s and master’s degrees holders: for subjects of security activity - specialty 076 «Entrepreneurship, Trade and Exchange Activity», and for subjects of state security bodies - specialty 251 «State Security».
On the basis of the conducted research, suggestions were made regarding the improvement of the Law of Ukraine «On Security Activities» dated March 22, 2012 and the Licensing Conditions for the Conduct of Security Activities, which were approved by the Resolution of the Cabinet of Ministers of Ukraine dated November 18, 2015 No. 960.
Principle of scientific support of rulemaking and construction of criminal law norms
Authors: Melnyk V. M.
Published: September 2024

The article highlights the issue of the principle of scientific support for the construction of criminal law provisions as one of the fundamental principles of rulemaking in the field of criminal law. This principle is based on the legislator’s obligation to adhere to the scientific approach and scientific methods at all stages of the rulemaking process, and this implies that such criminal law rulemaking decisions should be made which correspond to the level of scientific development of the relevant issue in the theory of criminal law and guarantee the actual implementation of the principle of legality in rulemaking in this area. The author suggests that in order to fully realize the potential of the principle of scientific support for rulemaking in the field of criminal law, it is advisable to combine its use with the principle of practical compliance of criminal law provisions and the possibilities of their application. This principle should be taken into account both in the process of updating criminal legislation in general and in the development of individual criminal law provisions. The principle of scientific support for the construction of criminal law provisions may not be taken into account when adopting laws of Ukraine on criminal liability in an extraordinary period, as exemplified by the beginning of the full-scale invasion of Ukraine by the Russian Federation. The need for an immediate state response to such global threats by adjusting the current criminal legislation without observing the principle of scientificity is exceptional. As a rule, the adoption of new criminal laws without observing the principle of scientific evidence results in low quality criminal law provisions that are not able to ensure their effective application. The principle of scientific support should be implemented both during the scientific examination of draft criminal laws and during the scientific support of the entire rulemaking process.
The victim and the subject as elements of the object of the «abuse of influence» offense
Authors: Mishura M.
Published: September 2024

The paper examines the features of the object of the crime provided for by Art. 369-2 of the Criminal Code of Ukraine, such as the victim and the subject of the crime.
It has been established that in the course of the commission of this offense, the victim is usually excluded. An exception is only the qualified structure of the crime, which is related to the demand of unlawful benefit (Part 3 of Article 369-2 of the Criminal Code of Ukraine). A natural person becomes a victim when extortion is committed, provided for in Part 3 of Art. 369-2 of the Criminal Code of Ukraine, since, as is known, extortion involves the threat of violence against the victim or his close relatives, restriction of the rights, freedoms or legal interests of these persons, damage or destruction of their property or property in their custody or under protection, or disclosure of information that the victim or his close relatives wish to keep secret.
The debatable issue regarding illegal gain as a subject or means of committing a crime, provided for in Art. 369-2 of the Criminal Code of Ukraine, has been researched. It has been argued that unlawful benefit should be recognized as the subject of this criminal offense, since the socially dangerous acts described in this article, which consist in the offer, promise or provision of unlawful benefit, as well as in the acceptance of the offer, promise or receipt of unlawful benefit, are committed for the purpose of unlawful benefit, regarding it, as well as the presence of such a criminal offense as abuse of influence is connected with its properties. At the same time, the unlawful benefit specified in Art. 369-2 of the Criminal Code of Ukraine cannot facilitate the commission of this crime, since the actual actions in relation to it constitute criminal influence. This crime is embodied precisely in the actions regarding the wrongful gain. Without illegal benefit, there will be no act, and therefore there is no reason to talk about ensuring its commission or facilitating it.
It has been determined that an unlawful benefit could be the means of committing a criminal offense only if the provision of Art. 369-2 of the Criminal Code of Ukraine covered the actual criminal influence on decision-making by a person authorized to perform the functions of state or local self-government.
Threat in the context of identifying the victim
Authors: Tkachenko I.
Published: September 2024

It is indicated that an important feature of the injured person, which allows to distinguish him from other persons, is related to the infliction of damage. The etymological and semantic analysis of the term «victim» shows that damage is an integral feature of a victim.
The article examines the possibility and expediency of recognizing a person as a victim in the criminal law field in the event of a threat to cause harm to him. Provisions of the current Criminal Code of Ukraine, the project of the new Criminal Code of Ukraine, national judicial practice are taken into account.
It is argued that in context of the injured person, term damage is understood in two meanings: 1) narrowly (includes only real damage); 2) in a broad sense (includes both damage and the danger/threat of causing it, as well as the threat). At the same time, attributing the threat as an independent action to a type of harm, as suggested by authors of the draft Criminal Code of Ukraine, seems debatable, because in such a case the term «threat» will denote both an action and a consequence. It is also worth paying attention to whether there is a need to use both the term «threat» and the term «danger» in the draft Criminal Code of Ukraine.
It has been established that the term «threat» in the context of the definition of the victim means both actual moral or other types of harm to him, as well as the threat/danger of his task.
It has been proven that victim in a certain composition of a criminal offense can be characterized not only by harm in its narrow sense, but also by threat or danger of its occurrence, that is, harm in the broad sense, as well as the threat of harm. The threat in the context of the criminal-legal understanding of victim is important, first of all, if there is no implementation. In case of the implementation of a threat, which is provided as an independent crime and is a stage of a single criminal activity, united by a single intention and aimed at causing damage to the same object, qualification under the article providing for responsibility for the threat is not required, and therefore and there is no need to establish the victim of the threat. If a threat is a way of committing an act, then the victim is determined in the context of act in general, taking into account the threat as a way of committing it.