bluuebunny/crossref_metadata_2025 huggingface dataset:
THE EFFECT OF DIALKYLDITHIOPHOSPHATE REAGENTS ON COPPER FLOTATION FROM PYRITIC SLAGS
Authors: Sabanova M. N. , Orekhova N. N. , Gorlova O. E. , Glagoleva I. V.
Published: September 2018

The paper studies the patterns of copper slag mineral phase separation by flotation depending on the modification of the additional BTF series collecting agent (dialkyldithiophosphate derivatives) and the ratio of main and additional collecting agent consumptions. The results of open and locked-cycle laboratory flotation tests are presented, and the effect of pulp pH on copper extraction is observed. The reasons for the copper extraction gain during grinding and subsequent flotation in acidic medium are analyzed. The aggregates of copper and iron sulfides are identified in slags thus proving decoppering effectiveness with a decrease in pH to slightly acidic values due to the active flotation of intergrown pieces of copper-containing phases with iron sulfide (pyrite, pyrrhotine). It is shown that the additional BTF series collecting agent added to the main collecting agent – potassium butyl xanthate – makes it possible to reduce the total consumption of the combined collecting agents while maintaining copper extraction and concentrate quality as compared to the consumption of only xanthate necessary to achieve the same parameters. The best results were achieved with the use of the BTF 1614 reagent in combination with potassium butyl xanthate at the BCC : BTF = 3 : 1 ratio. At an optimum pH = 5,5÷6,8, the increase in copper extraction to the concentrate was 11.13%, and gold and silver extraction increased by 9.68% and 9.93%, respectively.
Arsa ve Arazilere Yönelik Mali Yükümlülükler Çerçevesinde Kentsel Rantların Vergilendirilmesi
Authors: YAYĞIR Tacim , HACIKÖYLÜ Canatay
Published: September 2018

With urbanization, the values of immovables are changing positively for
various reasons. These increases in the value of the immovable are an important
part of urban unearned income. The main source of this increase in the value
of immovables is public goods and services. One of the most important problems
in urban unearned income is the land and land speculation. Those who
turn into land are able to unearned income (rant) that are seriously unfairly earning.
Some of the unearned income obtained from the value increases in the
immovables are required to be transferred to the public sector in order to
provide social justice. Taxation of these unearned income is the most important means of bringing urban unearned income to the public. In this study, financial
obligations in the Turkish tax system related to land and land were examined.
It can be said that the financial obligations in the Turkish tax system
concerning the main source of urban unearned income are not fully taxable on urban unearned income.
Pazar Tabanlı Yeteneklerin İşletme Performansı Üzerindeki Etkisi: Türkiye İmalat İşletmelerinde Bir Uygulama
Authors: Hamşıoğlu Ahmet Buğra , Durukan Tülin
Published: September 2018

Bu
çalışmanın amacı, kaynak tabanlı kuram ekseninde pazar tabanlı yetenekleri
incelemek ve bu bağlamda Türkiye imalat işletmelerinde pazar tabanlı
yeteneklerin işletme performansı üzerindeki etkilerini belirlemektir. Türkiye
imalat işletmeleri listesine bağlı olarak büyük ve orta boy imalat işletmeler
belirlenmiştir. Belirlenen bu işletmelerden, 500 işletme yöneticisine anket
yöntemi uygulanarak araştırma gerçekleştirilmiştir. Elde edilen verilerin
analizinde; SPSS 16.0 paket programından yararlanılarak analiz edilmiştir.  Oluşturulan modeli ve hipotezleri test etmek
amacıyla kısmi en küçük kareler yöntemi kullanılmıştır. Araştırmada kullanılan
ölçeklerin geçerlilikleri ve güvenilirleri test edilmiş ve daha sonara hem
ölçüm modeli hem de yapısal model SMART PLS programı yardımı ile analiz
edilmiştir. Bu çalışmanın sonucu olarak, pazar tabanlı yeteneklerin işletme
performansı üzerinde doğrudan ve pozitif etkileri olduğu görülmüştür.
Friedrich August von Hayek Perspektifinden İktidarın Gücü ve Sınırları
Authors: Yolal Merve
Published: September 2018

Sınırlandırılmamış, hak ve yetkileri önceden belirlenmemiş bir devletin
varlığı bireylerin özgürlüğü açısından oldukça önemli bir tehdit
oluşturmaktadır. Çünkü, kanunla sınırları çizilmemiş her gücün sonucunda
keyfilik kavramı ortaya çıkmakta, baskı veya zora dayanarak istenilen her şeyin
yapılması sağlanmaktadır. Bu nedenle, Friedrich August von Hayek devletin
sınırsız güç ve yetkilere sahip olmasından ziyade, çerçevesi kanunlarla
belirlenmiş bir otoritenin olması gerektiği düşüncesini savunmaktadır. Bu çalışmanın
amacı, liberal düşünür Friedrich August von Hayek’in sınırlı iktidar-sınırlı
devlet anlayışından hareketle; devletin sahip olduğu yetkiyi hangi durumlarda (piyasa
ekonomisinde, hizmetlerin sunulmasında ve özgürlüklerin korunmasında) ve ne şekilde
kullanabileceğine dair düşüncelerini ortaya koymaktır.
Is there a Trade-off between Output and Unemployment? An Evidence from Okun’s Law for G-20 Countries
Authors: Acaroğlu Hakan
Published: September 2018

There
can be a trade-off between output and unemployment which is formally called in
literature as Okun’s Law for G-20 countries. The objective of this research is
to reconsider Okun’s Law for G-20 countries with time-series data over the
period 1991-2014. First order difference and “gap” specification methods are
used for testing the relationship. Three different filtering techniques;
Hodrick-Prescott (HP), Chiristiano-Fitzgerald (CF) and Butterworth (BW) are
conducted for the gap specification method. For all methods, the results
validate the existence of inverse relation between output and unemployment in most
of the countries. An interesting finding is China, Indonesia, Saudi Arabia and, Turkey
do not
satisfy the Okun’s coefficient with at least one of these filtering techniques.
It is understood that, Group of G-20 countries display different Okun’s
coefficients depending on their development structures and productivity
heterogeneities.
Hubungan Kebugaran Jasmani dengan Kemampuan Konsentrasi dan Respon Kortisol
Authors: Nuryadi Nuryadi , Negara Jajat Darajat Kusuma , Juliantine Tite , Slamet Suherman , Gumilar Agus
Published: September 2018

Penelitian ini bertujuan untuk menganalisis bagaimana hubungan antara kebugaran jasmani dengan kemampuan konsentrasi dan respon kortisol sebagai penanda biomolekuler pada siswa apakah mengalami tekanan atau tidak. Seseorang yang mempunyai kebugaran jasmani yang baik akan mengalami suplai darah yang membawa nutrisi dan kaya akan oksigen menuju otak akan lebih lancar dan mengakibatkan respon metabolisme seluruh tubuh yang baik sehingga dalam hal ini siswa yang mempunyai kebugaran jasmani yang tinggi akan mempunyai kemampuan konsentrasi yang lebih tinggi dan lama, selain itu respon kortisol akan mengalami penurunan yang sejalan dengan penurunan stres. Metode yang digunakan dalam penelitian ini adalah studi expost facto, dengan rentang waktu ± 20 (duapuluh) bulan. Pengambilan data secara acak berdasarkan letak geografis atau wilayah dataran tinggi dan dataran rendah berbagai wilayah kabupaten kota yang berada di provinsi Jawa Barat. Subjek penelitian melibatkan siswa kelas 4, 5 dan 6 dengan total jumlah subjek penelitian sebanyak 339 siswa, laki-laki 151 orang dan perempuan 137 orang. Hasil pengukuran kebugaran jasmani berdasarkan wilayah dataran tinggi dan rendah sebesar (199,99±24,68) vs (198,51 ± 25,01); kemampuan konsentrasi sebesar (81,34±30,14) vs (69,22±27,09); respon kortisol sebesar (0,145±0,151) vs (0,141±0,103). Berikutnya hasil analisis statistik uji korelasi spearman’s rho antara kebugaran jasmani dengan kemampuan konsentrasi berdasarkan wilayah dataran tinggi dan rendah menunjukkan (r 0,438**; kontribusi 19,18%) vs (r-0,055; besar 0,30%) kebugaran jasmani dengan respon kortisol (r -0,203*; kontribusi 4,12%) vs (r -0,291**; kontribusi 8,47%). Kesimpulan 1) terdapat korelasi positif dan kontribusi yang signifikan pada level 0,01 antara kebugaran jasmani dengan kemampuan konsentrasi di daerah dataran tinggi; 2) tidak terdapat korelasi dan kontribusi antara kebugaran jasmani dengan kemampuan konsentrasi pada daerah dataran rendah; 3) terdapat korelasi negatif dan kontribusi yang signifikan pada level 0,05 antara kebugaran jasmani dengan respon kortisol di daerah dataran tinggi; 4) terdapat korelasi negatif dan kontribusi yang signifikan pada level 0,01 antara kebugaran jasmani dengan respon kortisol di daerah dataran rendah.
Untappable Key Distribution System: a One-Time-Pad Booster
Authors: Barbosa G. A. , De Graaf J. van
Published: September 2018

The One-Time-Pad (OTP) protocol gives unconditional security
for the information being encrypted. Correctly implemented, not even
an adversary with a quantum computer can crack it. However, the need
of sharing in a secure way supplies of symmetric random keys turned the
method almost obsolete as a stand-alone method for fast and large volume
telecommunication. Basically, this secure sharing of keys and their
renewal, once exhausted, had to be done through couriers, in a slow and
costly process. This paper presents a solution for this problem providing a
fast and unlimited renewal of secure keys: An untappable key distribution
system is presented and detailed. This fast key distribution system utilizes
two layers of confidentially protection: 1) Physical noise intrinsic to the optical
channel that turn the coded signals into stealth signals and 2) Privacy
amplification using a bit pool of refreshed entropy run after run, to eliminate
any residual information. The resulting level of security is rigorously
calculated and demonstrates that the level of information an eavesdropper
could obtain is negligible. The random bit sequences, fast and securely
distributed, can be used to encrypt text, data or voice.
Future Internet and Reconfigurable Computing:Considerations on Flexibility and Security
Authors: Mesquita Daniel , Frosi Pedro
Published: September 2018

The Future Internet is expected to support services in both existing and new scenarios, in terms of mobility, quality, scalability and security, among other. In this work we present how reconfigurable Computing (RC) may contribute to build Future Internet (FI) flexibility and security. Therefore, we discuss some aspects of FI initiatives that can be addressed by Reconfigurable Computing. Then we show some features of the Reconfigurable Computing enabling technology – FPGA – which can help to build a more flexible and secure Future Internet. The concluding remarks concern the need to bring together FI and RC researchers.
AS AÇÕES COLETIVAS DE CONTROLE CONTRATUAL NO ÂMBITO DO CÓDIGO DE DEFESA DO CONSUMIDOR
Authors: Verbicaro Dennis
Published: September 2018

O presente artigo, por meio do método dedutivo e de pesquisa bibliográfica e jurisprudencial, visa destacar a relevância das ações coletivas de controle contratual para a proteção dos interesses transindividuais do consumidor, com especial destaque à ação declaratória de nulidade contratual e à ação constitutiva de revisão contratual com possibilidade de cumulação de pedidos condenatórios e/ou cominatórios. Nesse contexto, objetiva-se demonstrar que o dirigismo contratual previsto na lei 8.078/90 (Código de Defesa do Consumidor) influi na difusão de deveres éticos ao segmento empresarial, aperfeiçoa a aferição da vontade legítima do consumidor, garante o acesso à informação clara e qualificada quanto ao alcance das obrigações contratuais e, ainda, resguarda a satisfação do interesse social inerente à realização do negócio jurídico em si. Com base nessa constatação, a pesquisa conclui que as ações coletivas supracitadas propiciam o dirigismo contratual necessário nas atuais relações de consumo por meio de um modelo de instrumentalização processual sofisticado e eficiente.
PRECEDENTES NO CÓDIGO DE PROCESSO CIVIL DE 2015: OBSTÁCULOS PARA SEU USO ADEQUADO E SUSTENTÁVEL
Authors: Gomes Magno Federici , Oliveira Letícia Alves de
Published: September 2018

O presente estudo busca discutir os precedentes judiciais enquanto meio para a razoável duração do procedimento, resguardando a qualidade das decisões judiciais. Observa-se a grande importância da interpretação na formação e na aplicação dos precedentes e do respeito ao princípio do contraditório, ao dever de fundamentação e ao princípio da colegialidade no uso dos precedentes. Percebem-se questões prejudiciais para o bom julgamento que persistem no direito brasileiro, que o Código de Processo Civil de 2015 tem por objetivo combater. Utilizou-se no trabalho a metodologia teórica-documental, com raciocínio dedutivo. Conclui-se que os precedentes judiciais, se utilizados de maneira adequada e com respeito às balizas legais, são aptos para realizar os fins a eles destinados.
Remote Feelings: On Blind-Sighted Collaborations and Long-Distance Art Making
Authors: Johnson David , Grond Florian
Published: September 2018

This essay is an account of Remote Feelings, a collaborative art project conceived of by the authors in 2016. Shaped by sensory difference, remote location and the use of digital technology, namely 3D scanning and printing technology, this project, like this essay, explores haptic experience, the pairing of analogue and digital methods, and the work and influence of Austrian artist and innovator Raoul Hausmann (1886-1971). The essay also shares information on our individual artistic practices and preoccupations, including Florian Grond's use of digital information as a starting point for the exploration of sensory experience and David Johnson's use of his blindness to inform his search for a new aesthetics.
Blindness Arts: An Introduction
Authors: Thompson Hannah , Warne Vanessa
Published: September 2018

No abstract available.
The Gravity, The Levity: Let Us Speak of Tactile Encounters
Authors: D'Evie Fayen , Kleege Georgina
Published: September 2018

This paper will describe an artist-curatorial project by Fayen d'Evie and Georgina Kleege, working with the collection of the KADIST Art Foundation in San Francisco to investigate the radical potential of haptic criticism and tactile dialogue.
Review of More Than Meets the Eye: What Blindness Brings to Art
Authors: Chandler Eliza
Published: September 2018

No abstract available.
Special Ethical and Compliance Issues Regarding Property Valuation Reports: Applicability of Valuations in Responsible Property Investment
Authors: Pilhál Zsolt
Published: September 2018

This paper presents some ethical and compliance aspects of valuations and demonstrates the importance of real estate appraisals in responsible property investment. The basis is fieldwork (interviews with senior Hungarian experts supported by questionnaires) focusing dominantly on the Hungarian practice and experience, combined with a review of the literature. This paper focuses on the operative side of investments: defining a detailed investment process, highlighting the unique features of ethical, responsible investments and then selecting the steps where an independent valuation is necessary and highlighting which aspects of ethical property investment should be supported by appraisals. The aims of this paper are 1) presenting the necessity of valuations, 2) giving examples when the independence of valuations is questionable.The conclusion is straightforward: independent appraisals are essential in all major milestones, but the independence aspect is critical. There are two practical ways to support this: 1) full implementation of professional standards (in developed property markets) and 2) centralized and common frameworks, rules and some “nudges” established by financial administration (in semi-developed markets like in Hungary).
Spectral, Thermal and In Vitro Antibacterial Studies on Cadmium(II)– bis(2,2/-methylidenephenol)diaminoethane
Authors: FELİX Nworie
Published: September 2018

The objective of this work is to prepare a new synthetic protocol of the cadmium(II) complex of bis(2,2’-methylylidenephenol)diaminoethane (H2BMPDE) and study the antimicrobial bioefficacy. In this work, we report the extractive method for the synthesis of cadmium(II) complex of  bis(2,2’-methylidenephenol)diaminoethane from salicylaldehyde, ethylenediamine, hydrochloric acid, and cadmium sulfate in a single, simple step. The ligand and the complex were characterized by FTIR, UV-Vis, 1H and 13C NMR, magnetic moment, GC-MS, thermal and elemental analysis. The chemical data indicated the formation of 1:1 (metal:ligand) mole ratio and distorted tetrahedral geometry was suggested as based on spectral data and magnetic moment. The results of preliminary antibacterial study revealed that Cd(II) H2BMPDE complexes prepared from different acids (HCl, HNO3, H2SO4) were effective against clinically important Gram-negative bacteria (Escherichia coli, pseudomonas, Klebsiella ) and Gram-positive bacterium (Staphylococcus aureus).The result indicated a new synthetic protocol for the synthesis of H2BMPDE complexes. On the application, H2BMPDE and its complexes could be considered as a potential antibacterial agent with further investigative analysis.
Adam Ważyk, the New Sentence and the question of entropy
Authors: Kaczmarski Paweł
Published: September 2018

In its first section, the article focuses on certain concepts belonging to Adam Ważyk’s theory of poetics. Specifically, I note the role of entropy in Ważyk’s thought on the form of the poem. Ważyk’s thinking of entropy served the poet to regulate his more general conception of the formal constitution of the poem. Although entropy seems to be an unavoidable process, the poet’s role and duty is to partly control it. For Ważyk, such partial containment of entropy is the condition of poetic communication.The second section of the article places the entropy-related tensions identified by Ważyk in the context of poetic debates of the 90’s between Fredric Jameson, a prominent Marxist critic, and the American poets identified as the LANGUAGE group.
“Alchemy and smoke in a bottle” – contemporary improvisational theater in Poland and the United States
Authors: Szuster Magdalena
Published: September 2018

The article is an attempt to capture improvisational theater as a modern dynamic phenomenon through analyzing its features, definitions and traits in order to characterize the genre and to systematize the current state of knowledge on the subject matter. By comparing and contrasting various aspects and notions of impro(v) in Poland and the United States, the study not only looks at the theater of improvisation through the prism of the “relocation” of the form from its original grounds and implementing it in within a different tradition, but also shows the experimental flexibility of the genre within different cultural traditions and structures. Based largely on interviews with Polish and American improvisers alike, this article is an in-medias-res case study of the contemporary improvised theater in Poland and the USA.
Editorial: Sociology of the Body—Research Practice in Poland
Authors: Byczkowska-Owczarek Dominika
Published: September 2018

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Superação do Planejamento Urbano Contemporâneo: apontamentos inspirados em Henri Lefebvre
Authors: Kauffmann Leivas Márcia Oliveira , Kleiman Mauro
Published: September 2018

Enfaticamente nas cidades globais e, em especial nas brasileiras, o processo de ocupação urbana de forma cada vez mais concentrada e densificada tem se refletido em impactos negativos nos recursos hídricos e ambientais. As cheias e inundações, associadas especialmente à crescente taxa de impermeabilização dos solos, denunciam um importante aspecto do quadro de insustentabilidade urbana que o planejamento não tem conseguido reverter. O presente artigo procurar contribuir na discussão de um novo aporte teórico-metodológico ao enfrentamento das questões urbanas, inspirado em Henri Lefebvre. Busca-se refletir sobre as contradições, dicotomias e tensões dialéticas entre pólos opostos identificáveis na dinâmica das cidades. Apresentam-se ainda alternativas em metodologias, na adoção da bacia hidrográfica como unidade integrada de gestão e planejamento e na utilização de novos indicadores de ocupação urbana sustentável, capazes de apontar novos caminhos de superação do planejamento urbano contemporâneo.
O papel do Poder Público Municipal na gestão dos recursos hídricos
Authors: Noronha Gustavo Carneiro de , Hora Mônica Aquino Galeano Massera da , Castro Elza Maria Neffa Vieira de
Published: September 2018

O presente artigo analisa a proposta de descentralização da gestão dos recursos hídricos no âmbito das microbacias hidrográficas, local onde se delimitam os problemas de âmbito municipal. Da análise do histórico da gestão das águas no país entende-se que os marcos legais estão inseridos em um processo de descentralização. A Constituição Federal de 1988 define que as águas são bens da União e Estados e, posteriormente, a Política Nacional de Recursos Hídricos institui as bacias hidrográficas como as unidades territoriais de gestão. Entretanto a fiscalização e a administração das bacias permanecem centralizadas e sem apresentar uma interconexão entre a utilização da água e os demais bens ambientais. Das atribuições municipais destacam-se a fiscalização do meio ambiente, a implantação da política agrícola, a criação de unidades de conservação e a gestão do território urbano. A incorporação dessas políticas em um zoneamento ambiental que insira a gestão das águas permite o melhor aproveitamento da disponibilidade hídrica e a participação da população local nas decisões administrativas das bacias hidrográficas através do governo municipal.
Processo de crescimento urbano-turístico: estudo do Balneário Meia Praia, no município de Itapema [Santa Catarina, Brasil]
Authors: Pinho Luciana , Reis Almir Francisco
Published: September 2018

Itapema localiza-se no litoral do Estado de Santa Catarina, no sul do Brasil, e sua história aponta para uma forte dinâmica urbana e crescente valorização turística. Este processo foi particularmente marcante no Balneário de Meia Praia, hoje caracterizada por grande densidade construtiva, verticalização e ocupação sazonal. Visando desvelar este processo, o presente trabalho estudou e reconheceu as formas de crescimento urbano em curso, a estrutura espacial do Balneário de Meia Praia e as relações ecológicas estabelecidas entre a ocupação antrópica e os ecossistemas naturais. Para tal, foi realizada análise evolutiva do seu traçado urbano e do modo como vem impactando as estruturas naturais. Ressaltando a relevância daqueles elementos mais permanentes, que subsistem apesar da intensidade e velocidade das transformações em curso, o trabalho aponta fortes indicativos para o planejamento urbano e ambiental, no sentido da construção de um futuro de cidade qualificada.
Hábitos e modos de vida no interior de Minas Gerais: uma contribuição ao debate sobre a relação cidade-campo no Brasil contemporâneo
Authors: Soares Josarlete Magalhães , Siolari Maristela , Dias Fabiana Silva
Published: September 2018

O objetivo foi investigar relações existentes entre o meio urbano e rural, a partir de padrões de consumo, comportamento e tipo de ocupação e verificar como esses meios têm dialogado, de maneira a contribuir para o conhecimento da realidade local e sobre os modos de organização social e econômica dentro do território brasileiro. O estudo realizado permitiu inferir sobre a necessidade de se incrementar pesquisas sobre o rural e as pequenas cidades no Brasil, a fim de conhecer melhor esses espaços e o sistema urbano brasileiro, explicitando tanto suas novas características como as permanências que ainda os fazem lugares diferenciados.
Re-examination of steel frame office buildings in preventing collapse when subject to intense fires
Authors: Korol Robert Mathews , Sivakumaran Ken S. , Heerema Paul
Published: September 2018

The purpose of the paper is to investigate the extent to which present-day design of steel framed buildings is susceptible to total collapse when subjected to extreme fire events. We select a 50 storey structure in which 2 and 4 adjacent storeys located at different above-ground heights are, in separate scenarios engulfed in raging fires. A total of 8 scenarios are analyzed, employing Newtonian mechanics and realistic energy dissipating properties of H-shaped columns and normal concrete floor slabs possessing secondary (shrinkage and temperature) reinforcement alone. While the present Canadian building code is the basis for our column designs, other standards provide very similar specifications. Although fire proofing is required in virtually all high rise building construction, we are excluding such materials in order to simplify the analyses, but clearly do not advocate its omission – quite the opposite in fact. As well, attributes such as floor beams, partitions and furnishings of every description, all of which would in practice participate in absorbing the kinetic energy of a crush-down upper block are excluded. Despite such a vast array of conservative assumptions, it is shown that partial collapse may occur during crush-down, however, in no case will total collapse be the consequence. These results should provide some comfort to code writers that their requirements should indeed prevent the most catastrophic of failures due to fires.
Analyzing pre-stressed steel arch beams
Authors: Polat Erkan , Çağlayan Barlas Özden
Published: September 2018

Techniques are being developed day-by-day to make it possible to pass through larger openings using smaller beam-column sections. Parallel to this trend, there is another necessity to produce not only smaller but also more economical and architecturally attractive beams. The aim of this study is to explain the structural behavior of steel arch beams reinforced using post-tension cables. Due to the effect of these, the arch beam load carrying capacity increases and a smaller sized optimized section can be obtained with a better architectural view. Moreover, it also allows better mechanical and applicable solutions for buildings. For a better understanding of the behavior of the reinforced beam, a steel beam and a steel arch beam with post-tensioned cables were modeled and analyzed using the SAP2000 finite element analysis computer program and compared with each other. In addition, full-scale specimens were prepared for testing to determine the structural behavior and compare the results with those from the computer modeling, the outcome of which was very promising. The similarity between the results inferred that no extra engineering knowledge and effort are needed to design such beams. The predicted (and proved by the testing) beam bearing capacity was 35% higher than that of the unreinforced beam. With just three full-scale tests completed, it was evident that the ratio (35%) could be increased by adjusting the cable post-tension force on much smaller sized beams.
Dahiliye Kliniklerinde Çalışan Hemşirelerin Konumlandırma Kullanım Özellikleri
Authors: ÇUVALCİ Burcu , HİNTİSTAN Sevilay
Published: September 2018

Özet Amaç: Son
yıllarda sağlık hizmetlerinde olan yenilikler, artan rekabet, tüketicilerin
bilinçlenmesi gibi durumlar hizmette bir adım öne geçmeyi, tercih edilen olmayı
zorunlu kılmaktadır. Farklı olmak ve bu olguyu sağlıklı/hasta bireyin zihnine
yerleştirebilmek tercih edilebilir olmayı ve marka olmayı beraberinde
getirmektedir. Bu nedenle hizmet, somut delillerle bireye sunulmalı ve zihninde
bir konum kazanmalıdır. Bu çalışmanın
temel amacı, “profesyonellik” ilkesinde, dahiliye kliniklerinde çalışan hemşirelerin
konumlandırma kullanım özelliklerini değerlendirmektir.Gereç ve Yöntem:
Tanımlayıcı nitelikte olan bu çalışma
Trabzon ilinde bir üniversite hastanesinde, 01-28 Şubat 2015 tarihleri arasında
gerçekleştirildi. Araştırmanın evrenini ve örneklemini dahiliye kliniklerinde
çalışan 186 hemşire oluşturdu ancak çalışma 170 hemşire ile tamamlandı.
Veriler, “Kişisel Bilgi Formu” ve “Konumlandırma Bilgi Formu” kullanılarak toplandı. Araştırma sonucunda elde
edilen veriler sayı, yüzde ve ortalama olarak değerlendirildi.Bulgular: Dahiliye kliniklerinde çalışan hemşirelerin %67.1’i lisans mezunu,
%84.1’i klinik hemşiresi ve çalışma süresi 9.0±7.3 yıldır. Hemşirelerin %86.5’i
“hastalar tarafından kaliteli hizmet veren bir hemşire olarak hatırlanmak
istediğini, %81.2’si “hemşirelik hizmeti sunarken olumlu davranış sergilemeye
özen gösterdiğini” belirtti. Hemşirelerin %77.6’sının “hemşirelik hizmetinin zihinlerde olumlu izler bırakması
için çaba sarf ettiği”, %71.2’sinin “toplumun hemşirelik hizmetine nasıl
bakması gerektiğini düşündüğü” ve %70.0’inin “hemşirelik hizmetlerine olumlu
anlamlar yüklemeye çalıştıkları” saptandı. Sonuç: Bu çalışma, dahiliye kliniklerinde çalışan hemşirelerin
konumlandırma özelliklerinin belirlenmesinin ve geliştirilmesinin önemini
gösteren temel verileri sağlamaktadır. Bununla
birlikte, ülkemizde hemşirelik mesleğinin konumlanması ve hemşirelerin
konumlandırma özelliklerini değerlendiren daha fazla araştırmalara ihtiyaç
vardır.
Origem e histórico da "Rede Nós de Água": pesquisa, ensino e extensão participativa em conservação de recursos hídricos sob a perspectiva agroecológica
Authors: Dos Anjos Luan Ritchelle Aparecido , Maia Thais De Carvalho , Queiroz Pedro Henrique Da Silva , Guimarães Felipe Salgado de , Campos Raquel Amorim , Cardoso Tommy Flávio , Sousa Wanick Loureiro de
Published: September 2018

A "Rede Nós de Água" se origina de um processo de construção e sistematização de experiências agroecológicas emergentes na região de Araponga/MG no início dos anos 90, a partir de uma parceria entre o Centro de Tecnologias Alternativas da Zona da Mata (CTA-ZM), a Universidade Federal de Viçosa (UFV) e agricultores familiares da região. Destas experiências, surge a demanda pelo melhor entendimento sobre a dinâmica dos recursos hídricos nestes sistemas agroflorestais, incitando a criação, em 2009, do Grupo de Trabalho das Águas (GT-Água). A partir daí, inúmeras ações de formação e pesquisa foram iniciadas e outras entidades foram se associando ao grupo, constituindo, em 2014, a Rede Nós de Água, que atua em diversos municípios da Zona da Mata mineira e além, com técnicas e tecnologias sociais que promovam  a conservação dos recursos hídricos através de  metodologias colaborativas e participativas, visando a autonomia e construção coletiva do conhecimento agroecológico.
CARCINOGENICITY OF MALATHION AND ESTROGEN IN AN EXPERIMENTAL RAT MAMMARY GLAND MODEL
Authors: Calaf G. M.
Published: September 2018

Breast cancer is considered a major and common health problem in both developing and developed countries. The etiology of breast cancer, the most frequent malignancy diagnosed  in women in the western world, has remained unidentified. Chemicals as the  organophosphorous pesticide malathion have been used to control a wide range of sucking  and chewing pests of field crops, and are involved in the etiology of breast cancers. The  association between breast cancer initiation and prolonged exposure to estrogen suggests  that this hormone may also have an etiologic role in such a process. However, the key  factors behind the initiation of breast cancer remain to be elucidated. The effect of  environmental substances, such as malathion and estrogen was analyzed in an experimental rat mammary gland model. Different cytoplasmic proteins are key in the transformation of a  normal cell to a malignant tumor cell and among these are the Ras super family and Ras  homologous A (Rho-A). Both types of proteins were greater in animals treated with  malathion than those with estrogens. E-Cadherins constitute a large family of cell surface  proteins.

Resultsshowed greater expression of E-Cadherin and vimentin than c-Ha-ras and Rho-A in  rats treated by estrogens. In breast cancer, analysis using immunohistochemical markers is  an essential component of routine pathological examinations, and plays an important role in  the management of the disease by providing diagnostic and prognostic strategies.

The aimof the present study was to identify markers that can be used as a prognostic tool for breast cancer patients.
The spectrum of BRCA1 gene mutations in early onset breast cancer patients from Russia
Authors: Anisimenko M. S. , Paul G. A. , Kozyakov A. E. , Gutkina N. I. , Berdyugina D. A. , Garanin A. Yu. , Butorina A. V. , Gornostaeva E. V. , Khafizov K. F. , Vyatkin Yu. V. , Shtokalo D. N. , Kovalenko S. P.
Published: September 2018

Aim of the study. Aim of the study was to estimate the occurrence of pathogenic mutations in the BRCA1 gene in Russian breast cancer patients.

Material and methods. Complete coding sequence of the BRCA1 gene of 445 early onset  breast cancer patients (under 40 years) from Novosibirsk region (Russia) were analyzed by  targeted Next Generation Sequencing (NGS) using Ion Torrent platform. Results. Forty (9%) carriers of various pathogenic mutations were revealed. Thirty five (7,9%) patients  carried 5382insC mutation, described earlier as a founder mutation for Slavic population.  Five (1.1%) patients carried various pathogenic mutations, namely C61G, 462delCC, E143X,  4153delA, and IVS18+1G>T. Besides, 29 genetic variants with no clinical significance or with  unknown clinical significance were detected in BRCA1 gene among 445 early onset breast  cancer patients. Conclusions. Data on the frequency of genetic variations in the BRCA1 gene among early onset breast cancer patients in the Novosibirsk Region (Russia) were  obtained. Proportion of the 5382insC mutation is 87.5% of all pathogenic mutations in the BRCA1 gene found in patients.
Enhancing EFL Learning in Cameroon’s Language Centres through Content and Language Integrated Learning
Authors: Akumbu Pius W. , Simo Charlotte D.
Published: September 2018

This study seeks to determine how Content and Language Integrated Learning (CLIL), already applied successfully in other parts of the world, could be adapted to teaching English as a foreign language in language centres in Cameroon. The problem identified was the fact that 43 out of 64 students leave language centres with a lot of general English but with little or no language abilities relevant to their fields of experience, whether academic or professional. The results revealed that the implementation of CLIL had a positive impact on learners’ development of diverse skills necessary for their success in academic and/or professional settings since there was a remarkable improvement in students’ performance in the experimental group (93%) as opposed to the limited (lower) performance of the control group (56.4%), providing therefore factual evidence of the effectiveness of the CLIL approach over other conventional approaches in meeting students’ needs and interests after training.
Chemical Constituents and Pharmacological Activities of Stellera chamaejasme
Authors: Li Xiao-Qin , Rahman Khalid , Zhu Jian-Yong , Zhang Hong
Published: September 2018

Background:

Stellera chamaejasme is a perennial weed and is found across a wide geographic range.
It is found in the Altai of eastern Russia, northern China and Mongolia southwards and reaches as far as the western
Himalayas of the Qinghai-Tibet and Yungui Plateaus. The dried roots of S. Chamaejasme are named “Rui-
Xiang-Lang-Du” and this herb with toxic properties is widely used in Traditional Chinese Medicine for the treatment
of various disorders. It is effective against dispelling phlegm by water and displays toxicity against insect
pests. This review provides a comprehensive overview of the chemical composition and the pharmacological
properties of S. Chamaejasme thus providing a better insight into its application in the prevention of human
disease.

Methods:

A comprehensive literature review was undertaken and the main chemical compounds found in S.
Chamaejasme were identified on the basis of their chemical formula and structure. These included flavonoids,
coumarins, lignans, diterpenoids plus others, and their pharmacological properties were also summarized in detail.

Results:

The main constituents of S. Chamaejasme included flavonoids, coumarins, lignans, diterpenoids plus
other compounds. The pharmacological properties of these compounds displayed a wide spectrum and include
anti-tumors, anti-viral, anti-bacterial, anti-convulsive, anti-epileptic, insecticide, anti-inflammation, regulation of
immunity etc. The diterpenoids were widely recognized as the constituent responsible for the anti-tumor effect.

Conclusion:

A large number of studies conclude that S. Chamaejasme displays a wide spectrum of pharmacological
activity with the anti-tumor activity being significant.
Protein-derived Smart Materials for Medical Applications: Elastin-like Polypeptides
Authors: Lin Rui , Wang Shanshan , Liu Wentian
Published: September 2018

A group of stimulus-responsive biopolymers developed from the hydrophobic domain of tropoelastin
is collectively known as elastin-like polypeptides (ELPs). These peptides generally consist of repeated pentapeptide
units of the form (VPGXG)n, where X can be any amino acid with the exception of proline. ELPs present
wide-ranging possibilities in biomedicine due to their many beneficial characteristics, including tunable phase
transition behavior and biological compatibility, along with the absence of immunogenic and pyrogenic characteristics.
The present paper reviews the physicochemical characteristics of ELPs and outlines a range of applications
in biotechnology and medicine.
New Trends in Liposome-based Drug Delivery in Colorectal Cancer
Authors: Krajewska Julia B. , Bartoszek Adrian , Fichna Jakub
Published: September 2018

Colorectal cancer (CRC) is one of the most common cancers in both men and women. Approximately
one-third of patients do not survive five years from diagnosis, which indicates the need for
treatment improvement, also through new ways of drug delivery. A possible strategy to increase treatment
efficacy is the use of liposomal formulation, which allows delivering both hydrophobic and hydrophilic
compounds with better biocompatibility and reduced side-effects. Liposomal formulations
showed better antitumor activity, longer drug accumulation and no cytotoxic effect on normal cells
when compared to free drugs. In this review, we will present liposomal preparations studied in CRC in
vitro and in vivo. We will focus on the advantages of liposomal delivery over conventional therapy as
well as modifications which increase specificity, drug accumulation and efficacy. Moreover, we will
discuss formulations investigated in clinical trials. Liposomal delivery has a great potential in overcoming
current limitations of cancer therapy and development of this system gives new perspectives in
CRC treatment.
Synthesis, Characterization and Antimicrobial Evaluation of Some N-Substituted Benzimidazole Derivatives
Authors: Kumar Anuj , Kumar Yogesh , Sahu Jagdish K. , Kumar Sushil
Published: September 2018

Background:

Due to the appearance of communicable microbial diseases and the toxicity related with presently used several antimicrobials such as β-lactam antibiotics, tetracyclines, quinolones, macrolides, glycopeptides (vancomycin) etc, demand for new antimicrobial agents has become a great concern in new technologies to improve efficacy and safety.

Methods:

In search of new antimicrobial agents with higher potency, some N-substituted benzimidazole derivatives (4, 5a-5h & 6) were obtained by chloroacetylation of benzimidazole followed by reaction with different amines, which were characterized by spectroscopic methods. All the target compounds were evaluated for their antibacterial and antifungal activity against microorganisms using two-fold serial dilution method.

Results:

Among the compounds evaluated, compounds 4 and 5d exhibited potent activity against Bacillus thuringiensis and Candida albicans while showed moderate activity against Escherischia coli when compared to amoxicillin and fluconazole. Compound 5a showed significant activity against tested microorganisms.

Conclusion:

From the current study, it may be concluded that synthesized compounds are fulfilling in terms of their structural distinctiveness and marked biological properties. These compounds might be encouraged to initiate a new class of antimicrobial agents.
Is there a Role for Sodium Orthovanadate in the Treatment of Diabetes?
Authors: Rana Divya , Kumar Anoop
Published: September 2018

Background:

Diabetes is a metabolic disorder, whose incidences are increasing day by day. Various classes of anti-diabetic drugs are clinically approved by the Food and Drug Administration (FDA) for the treatment of diabetes mellitus, but unfortunately, none of them is able to treat this condition. Thus, the exploration of novel mechanistic pathways of existing molecules may help to develop more safe and effective anti-diabetic agents. Sodium orthovanadate is a well known common laboratory agent used to preserve the protein tyrosyl phosphorylation state of the protein.

Methods:

The data related to sodium orthovanadate and diabetes mellitus has been collected from Pubmed.

Results:

Various reports have indicated the potential of sodium orthovanadate as Protein Tyrosine Phosphatase (PTP1B) inhibitors which play an important role in the pathogenesis of diabetes. However, safety of Sodium orthovanadate is still questionable.

Conclusion:

The sodium orthovanadate could be developed as an anti-diabetic agent. However, further studies are required to confirm its safety profile in the treatment of diabetes mellitus before starting a clinical trial.
Assessment of Duodenal Diverticula: Computed Tomography Findings
Authors: Yilmaz Erdem , Kostek Osman , Hereklioglu Savas , Goktas Muhammet , Tuncbilek Nermin
Published: September 2018

Aims:

To demonstrate the prevalence, accompanying pathologies, imaging and follow
up findings of Duodenal Diverticula (DD) with Multidetector Computed Tomography (MDCT).

Materials and Methods:

Consecutive 2910 abdominal MDCTs were retrospectively reviewed on
axial, coronal and sagittal planes. DD were evaluated for prevalence, location, number, size, contents,
diverticular neck, accompanying pancreaticobiliary pathologies, jejunal and colonic diverticula,
respectively.

Results:

DD were diagnosed in 157 cases (5.4%) and found mostly in the second part of the duodenum.
Juxta-ampullary DD was the most common type (78.3%) and mostly located ventral (n:86,
69.9%) to the ampulla of Vater. DD was solitary in 123 patients (78.3%) and more than one in 34
patients (21.7%). The median diameter of DD was 2.5 cm (range 1.5-3.6 cm) in the long-axis. The
lumen of DD contains air and contrast agent (n:96, 61.1%); air, contrast agent and debris (n:42,
26.7%) in most cases. Colonic diverticula (n:36, 22.9%), cholelithiasis (n:32, 20.4%), choledocholithiasis
(n:7, 4.4%), and biliary dilatation (n:8, 5.1%) were the most common additional
findings. Median follow-up time was 23 months (range 11 to 41 months). In three cases, new findings
(cholelithiasis, n:3, choledocholithiasis, n:1) were detected.

Conclusion:

Accompanying pathologies with DD diagnosis are valuable for physicians in order to
manage the patients. Following clinical and radiological features of well-diagnosed DD might reduce
the possible complications.
The Management of Newly Diagnosed HIV in a Sudanese Refugee in Canada: Commentary and Review of Literature
Authors: Sidhu Aven , Kakkar Rohan , Alenezi Osamah
Published: September 2018

Background:

Human Immunodeficiency Virus (HIV) prevalence rates in refugee camps are
inconclusive in current literature, with some studies highlighting the increased risk of transmission due
to poor living conditions and lower levels of education. With the increasing number of refugees from
HIV endemic countries, it is important to assess the programs established to support patients upon arrival.
Refugees have been reported to have a lower health literacy and face disease-related stigmatization,
which must be overcome for the lifelong treatment of HIV.

Case Presentation: 31-year-old female arrived in Canada as a refugee from Sudan with her 5 children
in July of 2017. She was diagnosed with HIV and severe dental carries during her initial medical
evaluation and referred to our centre. A lack of social support has resulted in severe psychological
stress. The first being stigmatization which has led to her not disclosing the diagnosis to anyone outside
her medical care team. Her level of knowledge about HIV is consistent with literature reporting
that despite HIV prevention programs in refugee camps, compliance with risk reduction behaviors, especially
in females, is low. Lastly, her major concern relates to the cost of living and supporting her
children.

Conclusion:

Assessment of current HIV programs is necessary to recognize and resolve gaps in the
system. Focusing on programs which increase both risk reduction behaviors in refugee camps and integration
of refugees in a new healthcare system can facilitate an easier transition for patients and aid
in the quest for global 90-90-90 targets for HIV.
Cerebrospinal Fluid, Brain Electrolytes Balance, and the Unsuspected Intrinsic Property of Melanin to Dissociate the Water Molecule
Authors: Herrera Arturo Solís , Ashraf Ghulam Md , del Carmen Arias Esparza María , Tarasov Vadim V. , Chubarev Vladimir N. , Avila-Rodriguez Marco F. , Makhmutovа Alfiya , Ganash Magdah , Mosa Osama F. , Hafeez Abdul , Bachurin Sergey O. , Aliev Gjumrakch
Published: September 2018

Background & Objective: Regulation of composition, volume and turnover of fluids surrounding
the brain and damp cells is vital. These fluids transport all substances required for cells and remove
the unwanted materials. This regulation tends to act as barrier to prevent free exchange of materials
between the brain and blood. There are specific mechanisms concerned with fluid secretion of the controlled
composition of the brain, and others responsible for reabsorption eventually to blood and the extracellular
fluid whatever their composition is. The current view assumes that choroidal plexuses secrete
the major part of Cerebrospinal Fluid (CSF), while the Blood-Brain Barrier (BBB) has a much less contribution
to fluid production, generating Interstitial Fluid (ISF) that drains to CSF. The skull is a rigid box;
thereby the sum of volumes occupied by the parenchyma with its ISF, related connective tissue, the vasculature,
the meninges and the CSF must be relatively constant according to the Monroe-Kellie dogma. This
constitutes a formidable challenge that normal organisms surpass daily. The ISF and CSF provide water and
solutes influx and efflux from cells to these targeted fluids in a quite precise way. Microvessels within the
parenchyma are sufficiently close to every cell where diffusion areas for solutes are tiny. Despite this,
CSF and ISF exhibit very similar compositions, but differ significantly from blood plasma. Many hydrophilic
substances are effectively prevented from the entry into the brain via blood, while others like neurotransmitters
are extremely hindered from getting out of the brain. Anatomical principle of the barrier
and routes of fluid transfer cannot explain the extraordinary accuracy of fluids and substances needed to
enter or leave the brain firmly. There is one aspect that has not been deeply analyzed, despite being
prevalent in all the above processes, it is considered a part of the CSF and ISF dynamics. This aspect is
the energy necessary to propel them properly in time, form, space, quantity and temporality.

Conclusion:

The recent hypothesis based on glucose and ATP as sources of energy presents numerous
contradictions and controversies. The discovery of the unsuspected intrinsic ability of melanin to dissociate
and reform water molecules, similar to the role of chlorophyll in plants, was confirmed in the
study of ISF and CSF biology.