bluuebunny/crossref_metadata_2025 huggingface dataset:
Avaliação de Sintomas Depressivos e Associação com a Limitação de Atividade em Pacientes Acometidos por Hanseníase em uma Unidade de Referência
Authors: Lima Celso Angelo Martins , Pires Carla Andrea Avelar , Delgado Danilo Souza , Bandeira Sabrina Sampaio
Published: May 2022

Objetivos: analisar a frequência de sintomas depressivos em pacientes acometidos por Hanseníase em uma unidade de referência no estado do Pará, além de correlacionar a incidência de sintomas depressivos em pacientes acometidos por Hanseníase com o grau de limitação de atividades e com o grau de incapacidade física. Metodologia: estudo transversal, observacional e descritivo, com o uso da escala de depressão de Beck e do Screening of Activity Limitation and Safety Awareness (Triagem de Limitação de Atividade e Consciência de Risco), que levou em consideração os pacientes acometidos pela hanseníase que fazem acompanhamento na Unidade de Referencia Especializada Marcello Candia. A casuística foi composta por 104 pacientes, de ambos os sexos. Resultados: presença de sintomas depressivos em 66,3% dos pacientes analisados, considerando um total de 14,4% com sintomas graves. Em relação à limitação de atividade, 73% dos pesquisados apresentavam algum grau de limitação de atividade, sendo que maior parte apresentava grau leve de limitação. Discussão: Houve correlação significativa entre o grau de incapacidade e a limitação física pela escala, visto que os pacientes com Grau II de incapacidade apresentavam uma média superior na escala quando comparados a pacientes com Grau 0. Conclusões: Os dados obtidos nesta pesquisa contribuem para que haja uma preocupação para além da integridade física do paciente com hanseníase, sinalizando a necessidade de um cuidado psicossocial e integral, o que deve incluir o rastreio de sintomas depressivos, além de intervenções clinicas e psicoterápicas no combate à depressão.
Câncer, dança e covid-19: Um relato de experiência sobre a OncoDance
Authors: Melnik Cristina Soares
Published: May 2022

Objetivo: Relatar a experiência da OncoDance, desde a sua origem até a nova configuração on-line, adaptada à pandemia. Metodologia: Trata-se de um estudo descritivo, do tipo relato de experiência, desenvolvido a partir das ações da OncoDance, tanto em formato presencial quanto em formato on-line. A análise de dados ocorre por meio da observação participante. Resultados e discussão: A OncoDance é uma oficina gratuita e sistemática de dança para quem tem ou teve câncer. O trabalho é voluntário, e começou em 2014, inspirado em resultados positivos de pesquisas científicas. Associada à prevenção do câncer e de outras doenças, a dança pode proporcionar diversos benefícios para pacientes oncológicos, tais como: a mudança de como o praticante de dança percebe a si mesmo, e de como se sente percebido pelo outro; a redução da percepção de dor; a valorização da alteridade; a melhora da autoestima e o bem viver. O formato on-line é uma adaptação aos tempos de covid-19, e amplia a oficina sistemática para acompanhantes e pessoas envolvidas no cuidado oncológico. Considerações finais: Dançar é uma atividade associada à saúde. Na configuração gratuita, sistemática e on-line, a OncoDance amplia as possibilidades de acesso, e possibilita o estímulo ao movimento, mesmo em períodos de isolamento social.
Compreensão de território nos serviços farmacêuticos da atenção básica à saúde: um estudo qualitativo
Authors: Schneider Loss Gabriel , Pegoraro Alves-Zarpelon Stella , Bueno Denise
Published: May 2022

Objetivo: descrever a compreensão de território por farmacêuticos que atuam na Atenção Básica. Métodos: Foram realizadas entrevistas com farmacêuticos alocados nas farmácias públicas de um município do Sul do Brasil. A entrevistas foram transcritas e analisadas por meio de análise temática de conteúdo. Resultados: Entrevistou-se treze farmacêuticos. As categorias temáticas elaboradas foram: território aprisionante, território distante e território desconhecido. Os resultados evidenciaram a atuação predominante do profissional como responsável pela gestão dos serviços farmacêuticos. A atuação profissional é dependente de recursos humanos e materiais adequados e da priorização de políticas de gestão voltadas à área da assistência farmacêutica. Conclusão: A compreensão do território nos serviços farmacêuticos da Atenção Básica à Saúde estabelece formas de atuação adequadas para tais serviços, no contexto dos 5.570 municípios contemplados na Política Nacional de Assistência Farmacêutica, conforme o preconizado na Lei 8.080/90.
Cuidado em saúde de pacientes insulinizados da Farmácia Municipal de um município da Região Metropolitana de Porto Alegre - RS
Authors: MIGLIORIN GRACIELI PILLA , Bueno Denise , Dos Santos Carine Libio
Published: May 2022

Este artigo objetivou estabelecer o perfil dos usuários com diabetes insulinizados e fatores associados ao autocuidado na sua terapêutica. Trata-se de um estudo quantitativo, descritivo, transversal, com amostra de 139 pessoas atendidas na Farmácia Municipal de São Leopoldo - RS. Utilizou-se a versão brasileira adaptada do "Questionário de Atividades de Autocuidado com o Diabetes”. Foram incluídas perguntas para avaliar o perfil sociodemográfico desses pacientes. O perfil dos usuários investigados foi: população idosa na faixa de 61 a 70 anos (29,5%), feminina (58,3%), com diabetes mellitus tipo 2 (64,0%), aposentados (39,6%) e com nível de escolaridade até o ensino médio incompleto (52,5%). Nas atividades de autocuidado, a menor adesão foi a realização de atividade física, dieta saudável e monitorização da glicemia capilar. A maior aderência foi no uso de insulina (média 6,56 ± 1,26). Conhecer o perfil dos usuários com diabetes insulinizados pode contribuir com o fortalecimento do autocuidado e contribuir na qualidade de vida destes pacientes.
Saberes e Fazeres Populares: o artesanato nas regiões turísticas de Alagoas
Authors: Cavalcante Mariana Magalhães , Vasconcelos Daniel Arthur Lisboa de
Published: May 2022

O artesanato é uma atividade baseada na transformação manual da matéria-prima em produtos criativos, de valor cultural, realizada por indivíduos que detém o conhecimento de técnicas específicas. Essa atividade tem uma estreita relação com atratividade turística de diversos territórios. O Estado de Alagoas, localizado na região Nordeste do Brasil, é dotado de um rico patrimônio cultural material e imaterial, possibilitando inúmeros recursos culturais favoráveis ao desenvolvimento e à ocorrência de movimentações turísticas que posam melhor valorizar esses patrimônios. Diante desse contexto, este estudo, de caráter qualitativo, exploratório e descritivo, visa identificar os territórios e as tipologias artesanais mais relevantes em Alagoas, tomando-se como base as regiões turísticas do Estado. O estudo aponta a correlação da predominância de determinados saberes e fazeres artesanais e a sua incidência nas regiões turísticas alagoanas.
Mulheres negras viajantes: experiências e relatos de um grupo de Facebook
Authors: Oliveira Natália Araújo de , Silva Priscilla Teixeira da , Almeida Helena de Jesus
Published: May 2022

Há poucas pesquisas no Brasil sobre experiências de mulheres negras viajantes, de modo a invisivibilizar um debate interseccional no setor. A partir desta realidade, o artigo tem o objetivo de investigar como a questão racial atravessa as experiências turísticas de mulheres negras. A pesquisa é resultante de uma netnografia realizada no grupo Viajantes Negros, do Facebook, composto por 3.720 pessoas, que foi acompanhado de 30 de janeiro a 15 de março de 2021. As 109 postagens realizadas no período foram categorizadas usando a análise temática e evidenciaram que as mulheres ali inseridas entendem a importância do corpo negro viajante ocupar todos os espaços – de maneira a mostrar que elas são turistas e não apenas trabalhadoras do setor –, contudo, foi possível notar um interesse maior por roteiros afrodiaspóricos. A pesquisa revelou ainda que o grupo é visto como um espaço seguro para troca de informações, que apenas mulheres negras compreendem – como dicas de locais onde o racismo é menos explícito, ou ainda experiências vinculadas a um suposto exotismo do corpo feminino negro. Como consideração final, aponta a necessidade de dar atenção ao movimento de viajantes negros do Brasil.
Practical work on project activities in packaging production
Authors:   Nosov Magnitogorsk State Technical University, Kaukina Ol'ga Valer'evna , Aver'yanova Tat'yana Aleksandrovna ,   Nosov Magnitogorsk State Technical University
Published: May 2022

This workshop was developed in accordance with the Federal State Educational Standard 3 ++ and the bachelor's degree curriculum in the field of training 29.03.03 "Technology of printing and packaging industries", profile "Branding and chemical modeling" in higher educational institutions. The workshop contributes to the formation of competencies in the discipline "Fundamentals of vocational and technical activities." It presents: graphic design of packaging, all practical work with a description of tasks and examples of the implementation of these tasks, as well as guidelines for the implementation of extracurricular independent work of students. The workshop is intended for students and teachers of higher educational institutions, a wide range of educational workers.
Estimation of Hormonal Seed Treatments on Enzyme Activities after Accelerated Ageing (Artificial Ageing) in Chickpea (Cicer arietinum L.)
Authors: Mishra Sachchida Nand , Kumari Neha , Mishra Namo Narayan , Mishra Kalpana
Published: May 2022

Background: Accelerated ageing, which is known to diminish seed viability and vigour in different seed crops, has been used to predict seed storability. The goal of this study was to see how accelerated ageing affected enzymatic characters of chickpea seeds (Variety Pusa 362). Seeds were exposed to accelerated ageing conditions by being heated to 35oC and 40oC and kept at 90% and 100% relative humidity at different duration i.e., 2, 4 and 8 days. After accelerating ageing pre sowing seed treatment with salicylic acid and gibberellic acid has done. The findings revealed that faster ageing causes the chickpea seed to degenerate, which is linked to a decline in enzymatic characters but hormonal seed treatments enhances enzymatic (amylase, catalase, peroxidase, dehydrogenase and protease) performance after ageing. Our result showed that antioxidant activity of aged seeds increased after seed treatment with plant growth hormones. Methods: The present experiment was conducted at state seed testing laboratory, Department of Genetics and Plant Breeding, SHUATS, Prayagraj, Uttar Pradesh during the year 2018 to 2020. In the experiment treatment were comprises with 37 treatment combination. The seeds are exposed to high temperatures and relative humidity in a chamber to speed up the ageing process. After that aged seed were invigorated with hormones i.e., hormonal seed priming. Result: Our finding revealed that the aged seed treated with gibberellic acid and salicylic acid enhanced the activity of antioxidant enzymes which help in seed germination.
​Effect of Sowing Dates on Phenological Traits, Yield and its Contributing Attributes on Snow Pea Genotypes
Authors: . Eshanee , Sharma Akhilesh , Sharma Parveen , Sharma G.D. , Manuja Sandeep , Rana Surinder Singh
Published: May 2022

Background: Precise knowledge of sowing date of a particular variety at a specific location is critical to achieve high yield. Keeping this in view, experiment was planned to assess the response of snow pea genotypes for sowing dates. Methods: Four genotypes namely, DPEPP-15-1, DPEPP-10-1, Arka Apoorva and Mithi Phali were sown on three sowing dates (21st October, 5th November and 20th November) in split plot design, replicated thrice at Palampur during winter 2018-19 and 2019-20 and observations were recorded on different yield attributes. Result: Early sown pea (21st October) resulted in early flowering and first picking, higher pod yield, pods/plant and harvest duration followed by 5th November sown crop. DPEPP-10-1 showed significantly superior performance for early harvest while DPEPP-15-1 was the most promising genotype followed by DPEPP-10-1 for yield and its contributing parameters. Genotypes DPEPP-15-1 and DPEPP-10-1 had advantage of 36 and 27% for fresh yield over variety Arka Apoorva respectively. Interaction between sowing dates and varieties revealed that sowing of DPEPP-15-1 on 21st October followed by 5th November had significantly higher pod yield, pods/plant and harvest duration followed by DPEPP-10-1 and they significantly outperformed other varieties Arka Apoorva and Mithi Phali.
On some classes of stationary inverse problems of determining the heat transfer coefficient for mathematical models of heat and mass transfer
Authors: Pyatkov Sergey G. , Belonogov Vladimir A.
Published: May 2022

In the article we consider well-posedness in Sobolev spaces of stationary inverse problems of recovering the heat transfer coefficient at the interface which is included in the transmission condition of the imperfect contact type. The existence and uniqueness theorem are exhibited. The method is constructive and the approach allows to develop numerical methods for solving the problem. The proof relies on a priori estimates obtained and the fixed-point theorem.
Deformations of biological tissues with photothermal nanoparticles under laser irradiation
Authors: Kasyanenko Ekaterina M. , Omelchenko Alexander I.
Published: May 2022

In this work, optical coherence tomography (OCT) of gel phantoms and cartilage tissue of the joint impregnated with nanoparticles was performed under laser exposure to an erbium fiber laser with a wavelength of 1.56 m. Multifunctional "magnetite + gold" nanoparticles with a "core-shell" structure were obtained by pulsed laser ablation of metals in a liquid, and oxide bronzes KxTiO2 and NaxTiO2 are formed in the processes of self-propagating high-temperature synthesis and mechanical activation. An improvement in the efficiency of the diagnostic method by introducing antireflection additives and absorbing nanoparticles due to a decrease in the irradiation intensity and an increase in the photothermal effect is shown. OCT elastography data indicate the dependence of tissue deformation on the preliminary history of tissue exposure.
Structural-phase inhomogeneity of aluminum films in multilayer systems
Authors: Snitovsky Yuri P.
Published: May 2022

The work is devoted to the study of the influence of the sequence of metal layers in two-layer films (Al 0.5% Ni)/Mo and composition SiO2/Si (111) on the phase composition and structural perfection of Al 0.5% Ni films. The samples used in the experiment were two-layer metal films (Al 0.5% Ni)/Mo and Mo/(Al 0.5% Ni), which were deposited on monosilicon substrates of orientation (111) and composition SiO2/Si (111). The influence of the arrangement of metal layers on the phase composition, crystallographic orientation of aluminum grains and their distribution over the thickness of Al 0.5% Ni films has been studied. It is shown that the annealing of the Al/Mo/Al system in an oxygen atmosphere significantly affects the density of oxides on the surface of the aluminum film, which is facilitated by the high affinity of aluminum for oxygen and the polymorphism of its compounds with oxygen in a wide temperature range.
Message from the Editor in Chief
Authors: Kurt Adile Askim
Published: May 2022

Dear reader,

Thank you for showing interest in the publication of Volume 7, number 1, 2021 issue of the Journal of Education and Special Education Technology. This issue aimed to present technologies related to inclusion education and intellectual disabilities. Based on the aim of this publication, 2 papers were selected that fully represent the aim of the issue.

The selected papers were authored by researchers from Italy. The selected papers include the following: Cultural accessibility of people with Intellectual disabilities: A pilot study in Italy;  Inclusion at the University through technology: A case study in Italy.

A major contribution to the success of this publication is the hard work of our researchers, editing team, and publishing team members. Therefore, we would like to acknowledge the contributions of all the contributors to this research. Dear reader, Enjoy reading!!

 

Best Regards,

Prof. Dr. Adile Askim Kurt, Anadolu University, Faculty of Education, Eskisehir, Turkey

(Editor-in-chief).
Conceptualization of Well-Building with Reference to Air-Filtration with Biomaterials
Authors: Shams Ghazaleh , Mahdavinejad Mohammadjavad
Published: May 2022

Aims: Over the last decade, green building standards and standard-setting organizations have made significant strides towards the market transformation of the building industry, resulting in a rapid expansion of green buildings and environmentally conscious building practices throughout the world. The WELL Building Standard focuses on the people in the building [1]. One of the biggest problems in the world today, that has devastating effects on human health and on global warming, is air pollution. By developing knowledge of biomaterials production, ways can be found to reduce these pollutants. Methods: To write this article, a quasi-experimental research method has been used that examines the production of a biomaterial for air filtration in building skins. This shell, which is inspired by cell plasma membrane, meets WELL standards for the adsorption of air pollutant particles and their conversion into harmless particles, thereby optimizing indoor air quality, as well as helping to reduce air pollutants and improve global warming conditions. The use of peptoids -non-natural mimetics of peptides and proteins and like cell membrane phospholipids- to make this synthetic membrane is recommended in this article. Findings: According to studies, peptoids can have side chains to adsorb air pollutant particles. The structure of peptoids allows them to exhibit certain features of cell plasma membrane, such as self-healing and self-assembly. These synthetic membranes can be fabricated with a structure like a cellular plasma membrane. Conclusion: This research states that the time has come to elevate human health and comfort to the forefront of building practices and reinvent buildings that are not only better for the planet, but also for people [1]. Fabricating synthetic membranes, for buildings, with air filtration capabilities using peptoids, is one way to maintain human health and improve the planet.
Percepción de la calidad en el servicio de delivery a través de Aplicativos Móviles de los usuarios que viven o trabajan en Lima Metropolitana de Nivel Socio Económicos A/B/C en el año 2019
Authors:   , Huapaya Alvarez José Eduardo , Samaniego Guevara Freddie David
Published: May 2022

Debido a los cambios tecnológicos experimentados en las últimas décadas, las tendencias del consumidor se han modificado drásticamente. Han cambiado los patrones de compra al igual que las necesidades y motivaciones de los consumidores. El internet transformó la lógica de la mercadotecnia, ya que cambió los tiempos y el acceso a la información al igual que el desarrollo y consolidación de un producto. En el caso del mercado de los teléfonos inteligentes, se vive un crecimiento exponencial, consecuencia de la cultura de la portabilidad, optimización del tiempo y la facilidad de compra. Esta situación ha generado que las empresas desarrollen aplicaciones (apps) que apoyen en el proceso de compra, cuyo diseño está orientado a satisfacer necesidades y crear relaciones duraderas con los clientes. Para la presente investigación, se estudiará la relación de los factores que más inciden en la percepción de la calidad del servicio de delivery a través de aplicativos móviles que emplean los usuarios que viven o trabajan en Lima Metropolitana del NSE A/B/C en el año 2019. El enfoque de la investigación fue mixto, en donde se realizó un estudio cualitativo, donde se empleó entrevistas a expertos en el rubro y en marketing digital. También se realizó un estudio cuantitativo mediante 314 encuestas al público objetivo para validar y complementar la información obtenida. Se obtuvo como principal hallazgo que sí existe relación significativa entre los factores de seguridad y empatía, que son los más influyentes en la calidad del servicio de delivery a través de aplicativos móviles.
Poeta wobec systemu. Duchowy świat poezji Liny Kostenko
Authors: Nowacki Albert
Published: May 2022

This paper is devoted to the analysis of selected poems by Ukrainian poet Lina Kostenko in the context of the sphere of spirituality and numerous references to biblical themes. The conducted analysis allows us to conclude that the world of religion and human spirituality allowed the poet to show a clear contrast between humanistic values and the dehumanized and oppressive reality of the communist system. The writer, who remains a symbol of the Ukrainian generation of the 1960s, reminded us that more important than conformist submission to the apparatus of power is maintaining her own dignity and fidelity to the values she professes, even when it is necessary to pay a high price, which the ban on publishing her works must have been for her.
Poetycka alchemia Liny Kostenko
Authors: Matusiak Agnieszka
Published: May 2022

The presented text is an attempt to define the key poetic coordinates of the works of Lina Kostenko — the most outstanding representative of the Ukrainian generation of the 1960s.
Digital etiquette in the views of students (based on the materials of the Yaroslavl Region)
Authors:   Yaroslavl State Pedagogical University, Talanov Sergei L.
Published: May 2022

The article analyzes students' ideas about digital etiquette. The author conducted a sociological study among students of leading universities in Yaroslavl. Comparative and typological analysis of digital etiquette among students from different families (material, educational differences in their parents), allowed us to identify the features of digital etiquette in the studied groups. It was found that students from families that belong to highly resource groups know the rules of conflict-free communication better than boys and girls from families that belong to medium and low resource groups. In addition, it was found that, according to respondents, deception and violation of personal space are the strongest conflict in the digital space. At the same time, for girls, regardless of the material well-being of their family, the observance of etiquette is more important than for boys. Respondents from highly resource groups, regardless of gender characteristics, are better informed about how to use a cell phone and gadgets while at university, at home, in a theater, train, shopping mall, etc. It was revealed that students from families who belong to medium and low resource groups were more likely to encounter bullying in the virtual world during their studies at the university. At the same time, girls faced cyber bullying more often than boys. The higher the level of education and the level of material well-being of students’ parents, the more well-thought-out strategy and tactics against cyber bullying their children have. Students from families who belong to low resource families in the online space are inclined to cyber bullying. It has been established that girls have more fake accounts than boys. At the same time, it was revealed that one-fourth of the surveyed young men from medium and low resource groups had a fake account created in a female name. Thus, this group of young men studies the values, interests, and needs of women. Such an account allows you to be added to women’s groups and analyze the values and needs of girls. It was revealed that girls from medium and low resource groups are more irritated by spelling mistakes when communicating on social networks than boys, as well as when their personal boundaries are violated. Activities aimed at improving students' knowledge, skills and abilities on digital etiquette are offered.
Relation of individual psychological characteristics to suicidal behavior of High School students
Authors:   I.G. Petrovsky Bryansk State University, Golubeva Galina F. , Feshchenko Elena M.
Published: May 2022

The article analyzes the features of the individual psychological characteristics of high school students and their manifestations of suicidal risks. The results of studying the propensity to suicidal reactions are presented. The analysis of data on the main components of suicidal behavior (demonstrativeness, affectivity, uniqueness, failure, maximalism, time perspective) is carried out. The features of accentuations of the character and temperament of high school students, the level of their intellectual development are considered. The relationship of these phenomena with suicidal behavior is determined, confirmed by a correlation analysis of the data.
Cost-effectiveness of colonoscopy and related procedures: population screening perspectives
Authors: Hsu Wen-Feng , Chiu Han-Mo
Published: May 2022

Colorectal cancer (CRC) screening can reduce the incidence and mortality of CRC, and many countries with moderate-to-high incidences of CRC have implemented population screening programs. Colonoscopy plays a pivotal role in the context of CRC screening as the primary screening modality, the diagnostic exam after a positive noninvasive test, the therapeutic procedure for resecting detected neoplasms, and the surveillance exam after the removal of neoplastic lesions. Although colonoscopy outperforms other noninvasive tests in detecting colorectal neoplasms, it is associated with higher cost, manpower, and invasiveness. Owing to the heterogeneity of healthcare systems in terms of the scale of health revenue, population demographics, and the payment systems in each country, the optimal or most cost-effective screening strategy may vary. Accordingly, economic appraisal of different approaches is essential, especially in organized screening programs within which the resources and the clinical capacity are constrained, and each step of the screening flow needs careful monitoring. The therapeutic procedures applied to manage screening-detected lesions and subsequent surveillance procedures also contribute to substantial additional costs. The level of willingness to pay is affected by various factors, including demographics, income, educational level, and health consciousness, and largely affects the optimal strategies. Herein, we systematically review and summarize the current evidence regarding the cost-effectiveness of colonoscopic screening, related therapeutic procedures, and subsequent surveillance and provide a balanced view from the perspective of population screening programs. It was revealed that 10-year colonoscopy is the most effective strategy compared to other strategies under the higher willingness-to-pay threshold or low colonoscopy cost. There are, however, discrepancies in the results among studies from different countries, which could be associated with the different cost parameters and assumptions used in the models. As for various therapeutic procedures for colorectal neoplasms such as polypectomy, endoscopic mucosal resection, or endoscopic submucosal dissection, strategies based on the risk of advanced histology or deep submucosal invasion based on image-enhanced endoscopy are the least expensive and avoid more recurrences. Furthermore, subsequent surveillance strategies that are based on the risk of CRC are more cost-effective. This article provides a comprehensive review of the literatures and a balanced view from the perspective of population screening programs.
Electroactive organics as promising anode materials for rechargeable lithium ion and sodium ion batteries
Authors: Li Xiang , Wang Yan , Lv Linze , Zhu Guobin , Qu Qunting , Zheng Honghe
Published: May 2022

Electroactive organics have attracted significant attention as electrode materials for next-generation rechargeable batteries because of their structural diversity, molecular adjustability, abundance, flexibility, environmental friendliness and low cost. To date, a large number of organic materials have been applied in a variety of energy storage devices. However, the inherent problems of organic materials, such as their dissolution in electrolytes and low electronic conductivity, have restricted the development of organic electrodes. In order to solve these problems, many groups have carried out research and remarkable progress has been made. Nevertheless, most reviews of organic electrodes have focused on the positive electrode rather than the negative electrode. This review first provides an overview of the recent work on organic anodes for Li- and Na-ion batteries. Six categories of organic anodes are summarized and discussed. Many of the key factors that influence the electrochemical performance of organic anodes are highlighted and their prospects and remaining challenges are evaluated.
Organization of lifelong education of library staff in the electronic environment
Authors: Kiseleva L. B.
Published: May 2022

The object of the report is to present a complex approach to lifelong professional education of library specialists in the digital environment, used in the Far Eastern State Scientific Library, to disclose the factors influencing quantitative and qualitative indicators in this sphere, to identify problematic and positive aspects based on the results of activities for the period of 2017–2021. The main attention is paid to the system of lifelong education of the staff of public libraries in the Khabarovsk Territory, closely related to the activities of the Center for Professional Development on the basis of the Far Eastern State Scientific Library, founded in 2002 with the support of the State Public Scientific and Technological Library of the Siberian Branch of the Russian Academy of Sciences and received the first license in the Far East to conduct educational activities on the basis of the library institution in 2004. Licensed programs of upgrading skills of library specialists of the region, short-term training in the framework of non-formal education, information and methodological support of educational activities (generation of information resources in modern formats in modern formats on current areas of library activity, development of network educational projects aimed at improving professional level of staff of the Far Eastern State Scientific Library and municipalities of the Khabarovsk Territory, support of professional skills competitions, analysis of the libraries activities) are examined. In the context of the digital space formation, the efforts of the Far Eastern State Library are aimed at interacting with partner libraries, providers of information resources, updating pedagogical tools with an emphasis on a competencybased approach, expanding the list of educational programs, introducing distance learning on additional professional programs, and providing open access to digitized educational resources.
US libraries in search for a standard model of reference services
Authors: Neshcheret M. Yu.
Published: May 2022

The article is about the evolution of reference service models in US libraries, starting with the development of a theoretical concept in the first half of the nineteenth century and ending with innovative models of today. The author’s object is to consider the main approaches to the organization of reference services, to give the description of the most common models, and to describe examples of their practical implementation in public and university libraries in the USA. The article reveals how reference librarians are trying to rethink, re-equip and modernize reference services with the help of experiments and initiatives for information interaction with users. The reference desk in the article is marked as the main “stumbling block” on the way to an ideal SBO model. A number of researchers believe that with the increase in the volume of available information and technological innovations, the previous organizational model hinders the effective use of library staff. The development of a reference service concept capable of providing an innovative competitive position that meets the future expectations of reference services users continues to be a key problem in the era of digitalization.
LIBWAY-2022: results and perspectives
Authors: Artemyeva E. B. , Minakov A. G.
Published: May 2022

Brief information is presented on the results of the International scientific and practical conference «Science, Technology, Information in Libraries (Libway-2022)», which continued the traditions of the 2018–2020 forums. This year, the participants discussed topical issues, practices and research in the field of scientific communications and the organization of science, book culture and library and information activities. The papers and messages presented at the plenary session, section sessions, round tables and panel discussions are characterized. The moderators of the events provided information about the work of the meetings.
The Development of iDPC-STEM and Its Application in Electron Beam Sensitive Materials
Authors: Wang Hongyi , Liu Linlin , Wang Jiaxing , Li Chen , Hou Jixiang , Zheng Kun
Published: May 2022

The main aspects of material research: material synthesis, material structure, and material properties, are interrelated. Acquiring atomic structure information of electron beam sensitive materials by electron microscope, such as porous zeolites, organic-inorganic hybrid perovskites, metal-organic frameworks, is an important and challenging task. The difficulties in characterization of the structures will inevitably limit the optimization of their synthesis methods and further improve their performance. The emergence of integrated differential phase contrast scanning transmission electron microscopy (iDPC-STEM), a STEM characterization technique capable of obtaining images with high signal-to-noise ratio under lower doses, has made great breakthroughs in the atomic structure characterization of these materials. This article reviews the developments and applications of iDPC-STEM in electron beam sensitive materials, and provides an outlook on its capabilities and development.
Analysis of age-specified prevalence and multiple HPV-type prevalence in a Chinese population
Authors: Zhou Yu-Xia , Zhang Yan-Ping , Wang Ting-Ting , Qu Xiao-Li , Zhang Xiao-Qian
Published: May 2022

Background
The human papillomavirus (HPV) is one of the most widespread viruses on the planet. A previous study found that HPV prevalence has an age-related relationship. Multiple HPV infections have a bad outcome. HPV infection is linked to uterine cervical cancer, bacterial vaginitis, cervicitis, fungal vaginitis, and pelvic inflammation, among other gynecological conditions. Furthermore, HPV infection during pregnancy has a negative impact on the health of both the mother and the fetus. In Chinese women, the prevalence of HPV and the link between HPV infection and various diseases are still unknown.
Methods
A Genotyping Test Kit was used to determine individual HPV genotypes (Life River Co., Shanghai, China). The prevalence of HPV types and ages was collected and analyzed by using SPSS 22.0 software.
Results
The HPV infection positive rate was 20.3% overall, including HPV single genotype (74.3%), HPV double genotype (18.4%), and HPV triple infections (7.4%). The top fifth prevalent HPV genotypes were HPV52 (25.5% of the positive individuals), HPV16 (19.7%), HPV58 (21.7%), HPV51 (11.4%) and HPV39 (9.6%). The < 20-year old group represented highest HPV infection rate, and HPV infection rates rise with age, especially multiple HPV infection rates. There were significant differences for fungal vaginitis (P = 0.010; χ2 = 6.61) and cervical lesions (P = 0.000; χ2 = 1069.60) with the health check group. The prevalence of HPV infection is significant popular among fungal vaginitis (P = 0.010; χ2 = 6.61) and cervical lesions (P = 0.000; χ2 = 1069.60). The early pregnant women, middle-late pregnant women HPV positive ration was lower than routine health checks HPV infection rates. hpv52: hpv58 enjoy the highest infection rate among the multiple HPV combination.
Conclusion
HPV infection was serious among women in China. HPV infection is linked to one's age in Chinese. Women under the age of 20 have the highest HPV prevalence, implying that HPV vaccination is required for young people. Multiple HPV infections have a cumulative effect as people become older. It's possible that HPV infection is linked to vaginitis since vaginitis makes you more susceptible to infection. HPV infections in pregnant women are common and require additional care.
Towards In Vivo Proof-of-Binding of 18F-labeled Inhibitor [18F]TRACK to Peripheral Tropomyosin Receptor Kinases
Authors: Wuest Melinda , Bailey Justin J , Dufour Jennifer , Glubrecht Darryl , Omana Vanessa , Johnston Tom H. , Brotchie Jonathan M. , Schirrmacher Ralf
Published: May 2022

Background
Tropomyosin receptor kinases (TrkA, TrkB, TrkC) are a family of tyrosine kinases primarily expressed in neuronal cells of the brain. Identification of oncogenic alterations in Trk expression as a driver in multiple tumor types has increased interest in their role in human cancers. Recently, first and second generation 11C and 18F-labeled Trk inhibitors e.g.[18F]TRACK have been developed. The goal of the present study was to analyze the direct interaction of [18F]TRACK with peripheral Trk receptors in vivo to prove its specificity for use as a functional imaging probe.
Methods
In vitro uptake and competition experiments were carried out using the colorectal cancer cell line KM12. Dynamic PET experiments were performed with [18F]TRACK, either alone or in the presence of amitriptyline, an activator of Trk, entrectinib, a Trk inhibitor, or unlabeled reference compound TRACK in KM12 tumor bearing athymic nude mice as well as B6129SF2/J and corresponding B6;129S2-Ntrk2tm1Bbd/J mice. Western blot and immunohistochemistry experiments were done with KM12 tumors, brown adipose tissue (BAT), and brain tissue samples.
Results
Uptake of [18F]TRACK was increasing over time reaching 208 ± 72% radioactivity per mg protein (n = 6/2) after 60 min incubation time. Entrectinib and TRACK competitively blocked [18F]TRACK uptake in vitro (IC50 30.9 ± 3.6 and 29.4 ± 9.4nM; both n = 6/2). [18F]TRACK showed uptake into KM12 tumors (SUVmean,60min 0.43 ± 0.03; n = 6). Tumor-to-muscle ratio reached 0.9 (60min) and 1.2 (120min). In TrkB expressing BAT [18F]TRACK uptake reached SUVmean,60min 1.32 ± 0.08 (n = 7). Activation of Trk through amitriptyline resulted in a significant increase of KM12 tumor uptake 23% (SUVmean,60min from 0.53 ± 0.01 to 0.43 ± 0.03; n = 6; p < 0.05) and in BAT 21% (SUVmean,60min from 1.32 ± 0.08; n = 5 to 1.59 ± 0.07; n = 6; p < 0.05). Immunohistochemistry showed TrkB > TrkA expression on BAT fat cells, but TrkA > TrkB in whole brain. WB analysis showed 7-fold higher TrkB expression in BAT versus KM12 tumor tissue.
Conclusion
The present data shows that radiotracer [18F]TRACK can target peripheral Trk receptors in human KM12 colon cancer as well as brown adipose tissue as confirmed through in vitro and in vivo blocking experiments. Higher TrkB versus TrkA protein expression was detected in brown adipose tissue of mice confirming a peripheral functional role of brain-derived neurotrophic factor in adipose tissue.
Green Ammonia: an opportunity towards carbon-free fuel
Authors: ADELI KHAOULA , AHMED SOUILHI , SAIFAOUI DENNOUN , ABDELKADER ALOUANI , ELMOUDEN MAHMOUD
Published: May 2022

The current energy buzz is all about alternatives-primarily biofuels, and reducing the use of carbon-based fuels and their emissions into the atmosphere is becoming increasingly important. this study presents an analysis of the new system in the development phase. Ammonia is a 100% clean liquid fuel that doesn’t require high pressure or cryogenic storage at room temperature and is comparatively easy to transport and store certainly compared to hydrogen. Our technological option is to replace the direct injection of the heat generated by the ammonia decomposition system in order to operate the engine pistons without having to change the engine components that must come into contact with ammonia, our invention includes an ammonia production unit using the gaseous mixture of hydrogen and nitrogen under stoichiometric condition’s, it is compressed at a pressure of 200 bars, with a temperature 450°C stored in a stainless steel tank, the ammonia gas flow from the tank into the ammonia cracker, the ammonia molecules each of which contain one nitrogen and three hydrogen atoms travel into the cracker system and flow upwards through the cracker chamber as ammonia comes into contact with the catalyst unit with a temperature of order of 900°C , mixture of 75% hydrogen and 25% nitrogen and heat released by this operation is introduced into the engine. Our invention makes it possible to combat the intermittency of renewable energies without footprint of nitrogen dioxide and carbon dioxide.
Estimated health-related physical fitness in Taiwan and its implications for body mass index distribution and overweight/obesity risk: Results from the Taiwan Scientific Physical Fitness Testing Program
Authors: Chen Yun-Tsung , Lee Po-Fu , Hung Chang-Tsen , Lin Chi-Fang , Hsu Chen-Te , Lin Yi-Tien , Lin Hsueh-Yi , Ho Chien-Chang
Published: May 2022

Background: Health-related physical fitness reduces the risk of chronic disease, promotes quality of life and has enormous economic benefits considering the global health care costs resulting from obesity. However, relatively limited information is available regarding the dose–response relationship between health-related physical fitness and obesity risk. This study aimed to determine the associations of health-related physical fitness with body mass index (BMI) distribution and overweight/obesity risk among adults aged 23-64 years in Taiwan.Methods: We conducted a cross-sectional study and reviewed the data derived from the Scientific Physical Fitness Testing Program, Sports Administration, Ministry of Education in Taiwan. Responses from 16,939 participants (7,761 men; 9,178 women) aged 23-64 years from the database were collected in this study. Each participant completed a series of health-related physical fitness measurements, including cardiorespiratory fitness (3-min progressive knee-up and step [3MPKS] test), muscular fitness (hand grip strength), and flexibility (sit-and-reach test). Anthropometric measurements included body height, weight, and BMI. The quartiles of health-related physical fitness results were identified as the dependent variable in the multiple linear and multiple logistic regression analysis to determine the associations of the health-related physical fitness measurements with the BMI distribution and the overweight/obesity risk as well as the dose–response relationship.Results: The 3MPKS test and relative hand grip strength were significantly negatively associated with BMI and overweight/obesity risk with a dose–response relationship in both men and women. However, the sit-and-reach test was partially related to BMI and overweight/obesity risk in adults.Conclusions: Higher levels of the 3MPKS test and relative grip strength were associated with lower BMI and overweight/obesity risk in both sexes. Cardiorespiratory fitness and muscular fitness were effective predictors of BMI distribution and overweight/obesity risk in Taiwanese adults.
Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage
Authors: Qiu Xiancheng , Tao Qianke , Zhang Lihan , Kuang Chenghao , Xie Yuke , Zhang Lifang , Yin Shigang , Peng Jianhua , Jiang Yong
Published: May 2022

Background
Microglial necroptosis exacerbates neurodegenerative diseases, central nervous system injury and demonstrates a pro-inflammatory process, but its contribution to subarachnoid hemorrhage (SAH) is poorly characterized. BCL-2 homologous antagonist-killer protein (Bak1), a critical regulatory molecule of endogenous apoptosis, can be involved in the pathological process of necroptosis by regulating mitochondrial permeability. Despite its possible significance in microglia necroptosis-mediated inflammation, few studies have investigated Bak1's role in microglia necroptosis regulation.
Methods
In vivo, an experimental subarachnoid hemorrhage in mice identified microglia necroptosis and adeno-associated virus targeted interference with microglia Bak1 to determine its effect on neuroinflammation. In vitro knockout of Bak1 in BV2 microglia identified its regulatory role in microglia necroptosis and neuroinflammation, and RNA-Seq clarified the potential downstream regulatory mechanisms.
Results
Microglia undergo necroptosis after subarachnoid hemorrhage in vivo and vitro. Knocked-down of Bak1 by adeno-associated virus attenuates microglial necroptosis, alleviates neuroinflammation, and improves neurological function after SAH. Increasing Bak1 expression and mediating BV2 microglia pro-inflammatory phenotype transformation, exacerbating oxidative stress and neuroinflammation. Abrogating Bak1 reduces necroptosis by downregulating the expression of phosphorylated pseudokinase mixed lineage kinase domain-like protein (p-MLKL), then downregulating pro-inflammatory phenotype gene expression. RNA-Seq shows that disrupting BV2 Bak1 downregulates multiple immune and inflammatory pathways and ameliorates cell injury by elevating Thrombospondin 1 (THBS1) expression.
Conclusions
Our finding demonstrated that deletion of bak1 alleviates microglial necroptosis, neuroinflammation and improved neurological functions after SAH, which was, at least in part, mediated by activation of THBS1 signaling pathway. Bak1 may be a potential therapeutic strategy for the management of SAH.
Automated external defibrillators and basic life support practices in secondary schools: A nationwide study
Authors: Abela Mark , Grech Victor , Sammut Mark Adrian
Published: May 2022

AimCardiac arrest prevention in schools has recently gained momentum. The survival benefit in schools who have access to defibrillators is clear, with far better survival outcomes in children or adults who sustain a cardiac arrest on school grounds. The main objectives of this study were to assess sudden cardiac arrest (SCA) prevention in Maltese schools, specifically the availability of defibrillators and staff competence in delivering resuscitation.Methodology and resultsAn online based questionnaire was distributed to all secondary schools across the Maltese archipelago. Data was collected, tabulated, and analysed using SPSS V.23. Most schools (n=40, 74.1%) completed the questionnaire. Two schools documented a SCA in the past 10 years. 87.5% agreed that SCA prevention is an important health topic. Most have a defibrillator on the premises (n=37, 92.5%). Only 1 defibrillator is usually available (n=27, 75.0%). Despite the majority claiming its ease of accessibility (n=35, 97.2%), most where not available on every floor (n=37, 97.2%). Only a third were close to a sporting facility (n=11, 30.6%). Schools do not organise regular resuscitation courses (n=21, 58.3%), with 8 schools having five or more certified staff members (23.5%). The number of defibrillators did not influence the frequency of CPR courses at school (p=0.607) and there was no association with the number of certified individuals (p=0.860).ConclusionDefibrillators are not readily available at secondary schools and are often installed in low risk areas. Most schools have only one staff member certified in resuscitation. These factors should be addressed with urgency.