bluuebunny/crossref_metadata_2025 huggingface dataset:
Nonemptiness of Brill–Noether loci in M(2,L)
Authors: Lange H. , Newstead P. E. , Strehl V.
Published: October 2015

Let [Formula: see text] be a smooth projective complex curve of genus [Formula: see text]. We investigate the Brill–Noether locus consisting of stable bundles of rank 2 and determinant [Formula: see text] of odd degree [Formula: see text] having at least [Formula: see text] independent sections. This locus possesses a virtual fundamental class. We show that in many cases this class is nonzero, which implies that the Brill–Noether locus is nonempty. For many values of [Formula: see text] and [Formula: see text] the result is best possible. We obtain more precise results for [Formula: see text]. Appendix A contains the proof of a combinatorial lemma which we need.
Influence of periodic traffic congestion on epidemic spreading
Authors: Zheng Muhua , Ruan Zhongyuan , Tang Ming , Do Younghae , Liu Zonghua
Published: October 2015

In the metropolis, traffic congestion has become a very serious problem, especially in rush hours. This congestion causes people to have more chance to contact each other and thus will accelerate epidemic spreading. To explain this observation, we present a reaction–diffusion (RD) model with a periodic varying diffusion rate to represent the daily traveling behaviors of human beings and its influence to epidemic spreading. By extensive numerical simulations, we find that the epidemic spreading can be significantly influenced by traffic congestion where the amplitude, period and duration of diffusion rate are the three key parameters. Furthermore, a brief theory is presented to explain the effects of the three key parameters. These findings suggest that except the normal ways of controlling contagion in working places and long-distance traveling, controlling the contagion in daily traffic congestion may be another effective way to reduce epidemic spreading.
Schrödinger equation of a particle in a uniformly accelerated frame and the possibility of a new kind of quanta
Authors: De Sanchari , Ghosh Sutapa , Chakrabarty Somenath
Published: October 2015

In this paper, we have developed a formalism to obtain the Schrödinger equation for a particle in a frame undergoing a uniform acceleration in an otherwise flat Minkowski spacetime geometry. We have presented an exact solution of the equation and obtained the eigenfunctions and the corresponding eigenvalues. It has been observed that the Schrödinger equation can be reduced to a one-dimensional hydrogen atom problem. Whereas, the quantized energy levels are exactly identical with that of a one-dimensional quantum harmonic oscillator. Hence, considering transitions, we have predicted the existence of a new kind of quanta, which will either be emitted or absorbed if the particles get excited or de-excited, respectively.
Optical dispersion functions of Co2−xEuxVSn using ab-initio calculations
Authors: Mahmoud Nada T. , Mousa Ahmad A. , Juwhari Hassan K. , Khalifeh Jamil M. , Abu-Jafar Mohammed S.
Published: October 2015

The magnetic, electronic and optical properties of [Formula: see text] alloys for selected concentrations (x = 0, 0.25, 0.50, 0.75 and 1.0) were investigated by means of density functional theory (DFT) calculations utilizing full potential linearized augmented plane wave (FP-LAPW) method. It was found that doping the [Formula: see text] alloy with rare-earth ions like Eu generates the nonstoichiometric [Formula: see text] and changes its original behavior from half ferromagnetic material to a metallic one. In addition, the total magnetic moment was found to increase with increasing dopant concentration with maximum local magnetic contributions on the Eu-sites. The optical dielectric functions as well as their static value for all the above alloys were also investigated. Moreover, the absorption coefficient, reflectivity and refractive indices were calculated. All the optical calculations were found to agree well with the band structure calculations when determining the alloys’ half-metallic behavior. Finally, the nonstoichiometric metallic compounds found in this series might be useful in the flat panel industry as potential phosphors.
Manipulation of pulse propagation in a four-level quantum system via an elliptically polarized light in the presence of external magnetic field
Authors: Karimi R. , Asadpour S. H. , Batebi S. , Soleimani H. Rahimpour
Published: October 2015

The influence of external magnetic field and relative phase between two electric field components of the probe field on absorption–dispersion and group index of a four-level atomic system with two degenerate sublevels are investigated. The results show that, the behaviors of weak probe light can be controlled by an external magnetic field. It is shown that in the presence of the external magnetic field the additional electromagnetically induced transparency (EIT) window can be obtained. Our result also reveal that the switching from slow to fast light or vice versa can be manipulated by changing the phase difference between the two circularly polarized components of a single coherent field.
Entanglement for excited states of ultracold bosonic atoms in one-dimensional harmonic traps with contact interaction
Authors: Peng Hsuan Tung , Ho Yew Kam
Published: October 2015

We have investigated quantum entanglement for two interacting ultracold bosonic atoms in one-dimensional harmonic traps. The effective potential is modeled by delta interaction. For this two-atom system, we have investigated quantum entanglement properties, such as von Neumann entropy and linear entropy for its ground state and excited states. Using a computational scheme that is different from previously employed, a total of the lowest 16 states are studied. Here we show the dependencies of entanglement properties under various interacting strengths. Comparisons for the ground state entanglement are made with earlier results in the literature. New results for the other 15 excited states are reported here.
BSIM4 to PSP Model Conversion: A Case Study
Authors: Grujić Dušan N. , Božović Mihajlo , Savić Milan
Published: October 2015

BSIM4 model is not suitable for distortion analysis of circuits with bias point [Formula: see text], such as passive mixers and RF switches, due to discontinuities in higher order derivatives. Surface potential based PSP model has continuous derivatives to at least third-order, and is therefore suitable for intermodulation products simulation. This paper presents the case study of BSIM4 to PSP model conversion flow and comparison of active and passive mixers and SPDT RF switch simulation results. Simulation results show good agreement of original BSIM4 and converted PSP models’ CV, IV, compression point, conversion loss and noise figure, which validates the conversion flow. The converted model has a correct third-order intermodulation products (IM3) slope of three, allowing the simulation of intermodulation products, which was not possible with the original BSIM4 model.
Admissible initial growth for diffusion equations with weakly superlinear absorption
Authors: Shishkov Andrey , Véron Laurent
Published: October 2015

We study the admissible growth at infinity of initial data of positive solutions of [Formula: see text] in [Formula: see text] when [Formula: see text] is a continuous function, mildly superlinear at infinity, the model case being [Formula: see text] with [Formula: see text]. We prove, in particular, that if the growth of the initial data at infinity is too strong, there is no more diffusion and the corresponding solution satisfies the ODE problem [Formula: see text] on [Formula: see text] with [Formula: see text].
Application of integral operator for vector-valued regression learning
Authors: Ma Yuanxin , Sun Hongwei
Published: October 2015

In this paper, the regression learning algorithm with vector-valued RKHS is studied. We motivate the need for extending learning theory of scalar-valued functions and analze the learning performance. In this setting, the output data are from a Hilbert space [Formula: see text], the associated RKHS consists of functions with values lie in [Formula: see text]. By providing mathematical aspects of vector-valued integral operator [Formula: see text], the capacity independent error bounds and learning rates are derived by means of the integral operator technique.
On Quantum Algorithm for Binary Search and Its Computational Complexity
Authors: Iriyama S. , Ohya M. , Volovich I.V.
Published: October 2015

A new quantum algorithm for the search problem and its computational complexity are discussed. Its essential part is the use of the so-called chaos amplifier, [8, 9, 10, 13]. It is shown that for the search problem containing [Formula: see text] objects time complexity of the method is polynomial in [Formula: see text].
A Numerical Modeling of A Vascular Implantable Cardiac Endovascular Assistant (AVICENA)
Authors: Rahmani Shahrokh , Tehrani Pedram , Karimi Alireza , Alizadeh Mansour , Navidbakhsh Mahdi
Published: October 2015

Cardiovascular diseases have been recently shown to have a pivotal role in human death and endangers lives of many people around the world. One of the most common cardiovascular diseases is poor performance of left ventricle. In this case, the ventricle cannot pump the blood into the aorta and circulatory system with a suitable power which is required for normal circulatory system. AVICENA is a new cardiac assist device which is implanted into the aorta to help the ventricle to pump the blood into circulatory system with more power and to make a better perfusion of the coronary arteries as well.

To reach a desire value of rotational speed of the pump, a control circuit is designed for counterpulsation of AVICENA based on the outcomes from previous studies. This control circuit uses a PID controller.

The present study aims to simulate the blood flow through the balloon part of AVICENA in a heart cycle with focusing on the calculation of its pump rotational speed by controlling the electrical current of the pump. Results revealed that the desired rotational speed of the pump can be achieved according to the previous aorta pressure cycle by electrical current control which is higher during balloon inflation in comparison with balloon deflation.

These findings may have implications not only for understanding the performance of AVICENA but also to help cardiac mechanics experts to improve the shortcoming of this newborn device.
Heavily Cr3+-modified Li4Ti5O12: An advanced anode material for rechargeable lithium-ion batteries
Authors: Lin Chunfu , Liang Guisheng , Gao Jinxiang , Deng Shengjue , Lin Shiwei , Li Jianbao
Published: October 2015

Heavily Cr[Formula: see text]-modified Li4Ti5O[Formula: see text] powders with a designed nominal composition of Li3Cr7Ti2O[Formula: see text] have been prepared by one-step solid-state reaction. X-ray diffraction (XRD) combined with Rietveld refinement indicates that these powders contain 96.5[Formula: see text]wt.% spinel Li[Formula: see text]Cr[Formula: see text]Ti[Formula: see text]O4 and 3.5[Formula: see text]wt.% Cr2O3. Due to the combination of Ti[Formula: see text]/Ti[Formula: see text] and Cr[Formula: see text]/Cr[Formula: see text] redox couples in Li[Formula: see text]Cr[Formula: see text]Ti[Formula: see text]O4 and the existence of Cr2O3, the composite exhibits a large first-cycle discharge capacity of 315[Formula: see text]mAh[Formula: see text] at a small current density of 62.5[Formula: see text]mA[Formula: see text]. Li[Formula: see text]Cr[Formula: see text]Ti[Formula: see text]O4 shows an improved Li[Formula: see text] ion diffusion coefficient and electronic conductivity, respectively arising from the small O[Formula: see text] ion fractional coefficient and unpaired 3d electrons in Cr[Formula: see text] ions. The majority of Cr2O3 is reduced to Cr after the first two lithiation processes, which benefits the electrical conduction between the Li[Formula: see text]Cr[Formula: see text]Ti[Formula: see text]O4 particles. Consequently, the composite exhibits a good rate performance and cyclability. Its capacity at 1000[Formula: see text]mA[Formula: see text] is as large as 141[Formula: see text]mAh[Formula: see text] with large retention of 90.1% after 100 cycles.
On the equitable vertex arboricity of complete tripartite graphs
Authors: Guo Zhiwei , Zhao Haixing , Mao Yaping
Published: October 2015

The equitable coloring problem, introduced by Meyer in 1973, has received considerable attention and research. Recently, Wu et al. introduced the concept of equitable [Formula: see text]-tree-coloring, which can be viewed as a generalization of proper equitable [Formula: see text]-coloring. The strong equitable vertex [Formula: see text]-arboricity of complete bipartite equipartition graphs was investigated in 2013. In this paper, we study the strong equitable vertex [Formula: see text]-arboricity of complete equipartition tripartite graphs. For most cases, the exact values of [Formula: see text] are obtained.
Some results on cyclic codes over ℤq + uℤq
Authors: Gao Jian , Fu Fang-Wei , Xiao Ling , Bandi Rama Krishna
Published: October 2015

Let [Formula: see text], where [Formula: see text] and [Formula: see text]. In this paper, minimum generating sets of cyclic codes over [Formula: see text] are given. A necessary and sufficient condition for cyclic codes over [Formula: see text] to be [Formula: see text]-free is obtained and a BCH-type bound on the minimum Hamming distance for them is also given.
Magnetic Coupling of Dissimilar ZnO–Co Granular Films Through a ZnO Spacer
Authors: Li Xiaoli , Jia Juan , Gao Yan , Gehring G. A. , Xu Xiaohong
Published: October 2015

An all-oxide granular film (GF) with a sandwich structure containing cobalt metal nanoparticles embedded in ZnO is fabricated by magnetron sputtering. Large and small Co particles can be obtained simultaneously in a sample by depositing nanostructured ZnO–Co layers at high and low temperatures, respectively. The two ZnO–Co layers couple with each other through a ZnO spacer layer, whose thickness tunes the strength of the coupling. Both the magnetic properties and the magnetoresistance (MR) of the samples depend on the sandwich structure. Magnetic interactions can be transferred through the polycrystalline pure ZnO spacer layer even when the layer is as thick as 40[Formula: see text]nm due to the long spin coherence length. An analysis of the data found that the spin coherence length was greater than [Formula: see text]17[Formula: see text]nm at room temperature (RT) in a polycrystalline film with very small grains. Tuning the resistance of the ZnO–Co layer deposited at a low temperature by adding aluminum so that it more nearly matches the resistance of the ZnO–Co layer deposited at a high temperature, dramatically enhances the MR of the sandwich sample. This study illustrates the power of combining films containing different sizes of nanoparticles in order to optimize the MR and so make the ZnO-based films more suitable for applications in spintronics.
Algorithm 954
Authors: Flocke N.
Published: October 2015

We report on an accurate and efficient algorithm for obtaining all roots of general real cubic and quartic polynomials. Both the cubic and quartic solvers give highly accurate roots and place no restrictions on the magnitude of the polynomial coefficients. The key to the algorithm is a proper rescaling of both polynomials. This puts upper bounds on the magnitude of the roots and is very useful in stabilizing the root finding process. The cubic solver is based on dividing the cubic polynomial into six classes. By analyzing the root surface for each class, a fast convergent Newton-Raphson starting point for a real root is obtained at a cost no higher than three additions and four multiplications. The quartic solver uses the cubic solver in getting information about stationary points and, when the quartic has real roots, stable Newton-Raphson iterations give one of the extreme real roots. The remaining roots follow by composite deflation to a cubic. If the quartic has only complex roots, the present article shows that a stable Newton-Raphson iteration on a derived symmetric sixth degree polynomial can be formulated for the real parts of the complex roots. The imaginary parts follow by solving suitable quadratics.
Algorithmic Differentiation of Numerical Methods
Authors: Naumann Uwe , Lotz Johannes , Leppkes Klaus , Towara Markus
Published: October 2015

We discuss software tool support for the algorithmic differentiation (AD), also known as automatic differentiation, of numerical simulation programs that contain calls to solvers for parameterized systems of
n
nonlinear equations. The local computational overhead and the additional memory requirement for the computation of directional derivatives or adjoints of the solution of the nonlinear system with respect to the parameters can quickly become prohibitive for large values of
n
. Both are reduced drastically by analytical (and symbolic) approaches to differentiation of the underlying numerical methods. Following the discussion of the proposed terminology, we develop the algorithmic formalism building on prior work by other colleagues and present an implementation based on the AD software dco/c++. A representative case study supports the theoretically obtained computational complexity results with practical runtime measurements.
Socializing by Gaming
Authors: Jia Adele Lu , Shen Siqi , Bovenkamp Ruud Van De , Iosup Alexandru , Kuipers Fernando , Epema Dick H. J.
Published: October 2015

Multiplayer Online Games (MOGs) like Defense of the Ancients and StarCraft II have attracted hundreds of millions of users who communicate, interact, and socialize with each other through gaming. In MOGs, rich social relationships emerge and can be used to improve gaming services such as match recommendation and game population retention, which are important for the user experience and the commercial value of the companies who run these MOGs. In this work, we focus on understanding social relationships in MOGs. We propose a graph model that is able to capture social relationships of a variety of types and strengths. We apply our model to real-world data collected from three MOGs that contain in total over ten years of behavioral history for millions of players and matches. We compare social relationships in MOGs across different game genres and with regular online social networks like Facebook. Taking match recommendation as an example application of our model, we propose SAMRA, a Socially Aware Match Recommendation Algorithm that takes social relationships into account. We show that our model not only improves the precision of traditional link prediction approaches, but also potentially helps players enjoy games to a higher extent.
The Hen or the Egg: Inflammatory Aspects of Murine MPN Models
Authors: Jutzi Jonas S. , Pahl Heike L.
Published: October 2015

It has been known for some time that solid tumors, especially gastrointestinal tumors, can arise on the basis of chronic inflammation. However, the role of inflammation in the genesis of hematological malignancies has not been extensively studied. Recent evidence clearly shows that changes in the bone marrow niche can suffice to induce myeloid diseases. Nonetheless, while it has been demonstrated that myeloproliferative neoplasms (MPN) are associated with a proinflammatory state, it is not clear whether inflammatory processes contribute to the induction or maintenance of MPN. More provocatively stated: which comes first, the hen or the egg, inflammation or MPN? In other words, can chronic inflammation itself trigger an MPN? In this review, we will describe the evidence supporting a role for inflammation in initiating and promoting MPN development. Furthermore, we will compare and contrast the data obtained in gastrointestinal tumors with observations in MPN patients and models, pointing out the opportunities provided by novel murine MPN models to address fundamental questions regarding the role of inflammatory stimuli in the molecular pathogenesis of MPN.
Gastrojejunal Anastomosis Perforation after Gastric Bypass on a Patient with Underlying Pancreatic Cancer: A Case Report and Review of the Literature
Authors: Bellorin Omar , Kundel Anna , Ramirez-Valderrama Alexander , Castro Armando
Published: October 2015

Introduction. We describe a case of gastrojejunal anastomosis perforation after gastric bypass on a patient with underlying pancreatic cancer.Case Description. A 54-year-old female with past surgical history of gastric bypass for morbid obesity and recent diagnosis of unresectable pancreatic cancer presents with abdominal pain, peritonitis, and sepsis. Computerized axial tomography scan shows large amount of intraperitoneal free air. The gastric remnant is markedly distended and a large pancreatic head mass is seen. Intraoperative findings were consistent with a perforated ulcer located at the gastrojejunal anastomosis and a distended gastric remnant caused by a pancreatic mass invading and obstructing the second portion of the duodenum. The gastrojejunal perforation was repaired using an omental patch. A gastrostomy for decompression of the remnant was also performed. The patient had a satisfactory postoperative period and was discharged on day 7.Discussion. Perforation of the gastrojejunal anastomosis after Roux-en-Y gastric bypass is an unusual complication. There is no correlation between the perforation and the presence of pancreatic cancer. They represent two different conditions that coexisted. The presence of a gastrojejunal perforation made the surgeon aware of the advanced stage of the pancreatic cancer.
Exploring Innovative Solutions for Quality of Life and Care of Bed-Ridden Nursing Home Residents through Codesign Sessions
Authors: van Hoof J. , Wetzels M. H. , Dooremalen A. M. C. , Overdiep R. A. , Nieboer M. E. , Eyck A. M. E. , van Gorkom P. J. L. M. , Zwerts-Verhelst E. L. M. , Aarts S. , Vissers-Luijcks C. , van der Voort C. S. , Moonen M. J. G. A. , van de Vrande H. A. , van Dijck-Heinen C. J. M. L. , Wouters E. J. M.
Published: October 2015

Bed-ridden nursing home residents are in need of environments which are homelike and facilitate the provision of care. Design guidance for this group of older people is limited. This study concerned the exploration and generation of innovative environmental enrichment scenarios for bed-ridden residents. This exploration was conducted through a combination of participatory action research with user-centred design involving 56 professional stakeholders in interactive work sessions. This study identified numerous design solutions, both concepts and products that are available on the marketplace and that on a higher level relate to improvements in resident autonomy and the supply of technological items and architectural features. The methodology chosen can be used to explore the creative potential of stakeholders from the domain of healthcare in product innovation.
Premalignant and Malignant Skin Lesions in Two Recipients of Vascularized Composite Tissue Allografts (Face, Hands)
Authors: Kanitakis Jean , Petruzzo Palmina , Gazarian Aram , Testelin Sylvie , Devauchelle Bernard , Badet Lionel , Dubernard Jean-Michel , Morelon Emmanuel
Published: October 2015

Recipients of solid organ transplants (RSOT) have a highly increased risk for developing cutaneous premalignant and malignant lesions, favored by the lifelong immunosuppression. Vascularized composite tissue allografts (VCA) have been introduced recently, and relevant data are sparse. Two patients with skin cancers (one with basal cell carcinoma and one with squamous cell carcinomas) have been so far reported in this patient group. Since 2000 we have been following 9 recipients of VCA (3 face, 6 bilateral hands) for the development of rejection and complications of the immunosuppressive treatment. Among the 9 patients, one face-grafted recipient was diagnosed with nodular-pigmented basal cell carcinoma of her own facial skin 6 years after graft, and one patient with double hand allografts developed disseminated superficial actinic porokeratosis, a potentially premalignant dermatosis, on her skin of the arm and legs. Similar to RSOT, recipients of VCA are prone to develop cutaneous premalignant and malignant lesions. Prevention should be applied through sun-protective measures, regular skin examination, and early treatment of premalignant lesions.
Occipital Condyle Fracture with Accompanying Meningeal Spinal Cysts as a result of Cervical Spine Injury in 15-Year-Old Girl
Authors: Wiktor Łukasz , Tomaszewski Ryszard
Published: October 2015

The occipital condyle fracture is rare injury of the craniocervical junction. Meningeal spinal cysts are rare tumors of the spinal cord. Depending on location, these lesions may be classified as extradural and subdural, but extradural spinal cysts are more common. We present the case of a 15-year-old girl who suffered from avulsion occipital condyle fracture treated with use of “halo-vest” system. We established that clinical effect after completed treatment is very good. Control MRI evaluation was performed 12 months after removal of “halo-vest” traction, and clinically silent extradural meningeal spinal cysts were detected at the ventral side of the spinal cord in the cervical segment of the spine. Due to clinically silent course of the disease, we decided to use the conservative treatment. The patient remains under control of our department.
Research on the Efficiency and Economic Impact of Energy-Saving Transformation of Residential Buildings in Different Climatic Regions of China
Authors: Liu Qibo , Feng Wei
Published: October 2015

In China, the transformation of existing buildings is confronted with various problems in aspects ranging from technology to policy and even to economic efficiency, which restrains the pace of existing building transformation. Aiming at these conditions, a building model is established with simulation software in the research herein to deeply analyze the energy-saving effect of building envelope transformation in different climatic regions and its economic efficiency based on regional and national policies. The research results show that any single technology is difficult to completely satisfy the requirements of current energy efficiency standards, and technical measures should be taken according to different climatic regions. For the northern heating area, the building envelope transformation must be carried out simultaneously with the transformation of heat metering. Policy formulation and fund determination for the energy-saving transformation of existing buildings in China should be more flexible based on transformation effect and rely more on social and commercial forces rather than solely on the promotion of government.
Anagrus breviphragmaSoyka Short Distance Search Stimuli
Authors: Chiappini Elisabetta , Berzolla Alessia , Oppo Annalisa
Published: October 2015

Anagrus breviphragmaSoyka (Hymenoptera: Mymaridae) successfully parasitises eggs ofCicadella viridis(L.) (Homoptera: Cicadellidae), embedded in vegetal tissues, suggesting the idea of possible chemical and physical cues, revealing the eggs presence. In this research, three treatments were considered in order to establish which types of cue are involved: eggs extracted from leaf, used as a control, eggs extracted from leaf and cleaned in water and ethanol, used to evaluate the presence of chemicals soluble in polar solvents, and eggs extracted from leaf and covered with Parafilm (M), used to avoid physical stimuli due to the bump on the leaf surface. The results show that eggs covered with Parafilm present a higher number of parasitised eggs and a lower probing starting time with respect to eggs washed with polar solvents or eggs extracted and untreated, both when the treatments were singly tested or when offered in sequence, independently of the treatment position. These results suggest that the exploited stimuli are not physical due to the bump but chemicals that can spread in the Parafilm, circulating the signal on the whole surface, and that the stimuli that elicit probing and oviposition are not subjected to learning.
Symmetric Dimethylarginine Is Not Associated with Cumulative Inflammatory Load or Classical Cardiovascular Risk Factors in Rheumatoid Arthritis: A 6‐Year Follow‐Up Study
Authors: Dimitroulas Theodoros , Hodson James , Sandoo Aamer , Smith Jacqueline P. , Douglas Karen M. , Kitas George D.
Published: October 2015

Symmetric dimethylarginine (SDMA) indirectly inhibits nitric oxide (NO) synthesis and predicts cardiovascular and all‐cause mortality in high‐risk patients. The aim of our study was to investigate the associations of cumulative inflammatory burden (assessed by serial measurements of inflammatory markers) and classical cardiovascular (CV) disease risk factors with SDMA in RA patients. 201 RA patients (155 females, median age 67 (59–73)) were assessed at baseline (2006). Classical CV disease risk factors were recorded and systemic inflammation was determined by the measurement of C‐reactive protein (CRP) and erythrocyte sedimentation rate (ESR). At follow‐up (2012) SDMA levels were measured by enzyme‐linked immunosorbent assay. Mean SDMA levels in RA population were 0.40 (0.40–0.53) μmol/L. No significant association between SDMA and cumulative inflammatory load was established in the analysis. SDMA levels were not found to be significantly related to CV disease risk factors. We explored the potential relationship between SDMA and cumulative inflammatory burden in patients with RA and obtained negative results. SDMA did not relate to CV disease risk factors in our population and its clinical significance as a surrogate marker of endothelial dysfunction in patients with RA remains to be determined.
Torque Analysis of a Triple Acid‐Etched Titanium Implant Surface
Authors: Pontes Ana Emília Farias , de Toledo Cássio Torres , Garcia Valdir Gouveia , Ribeiro Fernando Salimon , Sakakura Celso Eduardo
Published: October 2015

The present study aimed to evaluate the removal torque of titanium implants treated with triple acid etching. Twenty‐one rats were used in this study. For all animals, the tibia was prepared with a 2 mm drill, and a titanium implant (2 × 4 mm) was inserted after treatment using the subtraction method of triple acid etching. The flaps were sutured. Seven animals were killed 14, 28, and 63 days after implant installation, and the load necessary for removing the implant from the bone was evaluated by using a torque meter. The torque values were as follows: 3.3 ± 1.7 Ncm (14 days), 2.2 ± 1.3 Ncm (28 days), and 6.7 ± 1.4 Ncm (63 days). The torque value at the final healing period (63 days) was statistically significantly different from that at other time points tested (ANOVA, p = 0.0002). This preliminary study revealed that treatment with triple acid etching can create a promising and efficient surface for the process of osseointegration.
The Structure of Simple Modules of Birman-Murakami-Wenzl Algebras
Authors: Xu Xu
Published: October 2015

We study the restriction of simple modulesDf,λof Birman-Murakami-Wenzl algebrasBn(r,q)withq  being not a root of 1. Precisely, we study the module structure for the restriction ofDf,λtoBn-1(r,q)and describe the socle and head of the restriction of each simple module completely.
Splenosis: A Rare Etiology for Bowel Obstruction—A Case Report and Review of the Literature
Authors: Younan George , Wills Edward , Hafner Gordon
Published: October 2015

Splenosis is a historically uncommon etiology for bowel obstruction. Autotransplanted splenic tissues following surgery or trauma of the spleen are known to occur in multiple locations of the abdominal cavity and pelvis. The small bowel mesentery is a blood vessel-rich environment for growth of splenic fragments. We present a case of a 36-year-old male patient who sustained a gunshot wound to his left abdomen requiring a splenectomy and bowel resection fifteen years prior to his presentation with small bowel obstruction requiring exploration, adhesiolysis, and resection of the mesenteric splenic deposit. Our aim in this report is to provide awareness of splenosis as an etiology for bowel obstruction, especially with increased incidence and survival following abdominal traumas requiring splenectomies. We also stress on the importance of history and physical examination to include splenosis on the list of differential diagnoses for bowel obstruction.
Timing of First Antenatal Care Attendance and Associated Factors among Pregnant Women in Arba Minch Town and Arba Minch District, Gamo Gofa Zone, South Ethiopia
Authors: Gebremeskel Feleke , Dibaba Yohannes , Admassu Bitiya
Published: October 2015

Objective. To assess the timing of first antenatal care attendance and associated factors among pregnant women in Arba Minch Town and Arba Minch District, south Ethiopia.Method. Facility based cross-sectional study employing both quantitative and qualitative methods was conducted from February to March, 2014, in Arba Minch Town and Arba Minch District. Data were collected from 409 pregnant women attending antenatal care clinics in nine public health facilities using systematic random sampling. Analysis was done using SPSS version 20. Descriptive statistics and binary and multiple logistic regression analysis were done.Results. The mean (SD±) age of the respondents was 26 ± 5.5 years. The mean gestational age at first antenatal care attendance was 5 ± 1.5 months. This study indicated that pregnant women with low monthly income (AOR = 4.9, CI: 1.71, 14.08), women who did not receive advise on when to start ANC (AOR = 3, CI: 1.48, 6.24), women with household food insecurity (AOR = 4.66, CI: 1.007, 21.59) and women with unplanned pregnancy (AOR = 4.49, CI: 2.16, 9.35) had higher odds of late antenatal care attendance compared with their counterparts.Conclusions. The study showed that majority of the pregnant women attended late for first antenatal care. Hence, providing health education on the timing of antenatal care is important.
Everolimus in Metastatic Breast Cancer: Clinical Experience as a Late Treatment Line
Authors: Pouget Mélanie , Abrial Catherine , Planchat Eloise , Van Praagh Isabelle , Arbre Marie , Kwiatkowski Fabrice , Dubray-Longeras Pascale , Devaud Hervé , Dohou Joyce , Herviou Pauline , Mahammedi Hakim , Durando Xavier , Chollet Philippe , Mouret-Reynier Marie-Ange
Published: October 2015

Background: Everolimus (Afinitor®) plus exemestane are indicated for hormone receptor-positive, HER2/neu-negative metastatic breast cancer (MBC), in menopausal women without symptomatic visceral disease after recurrence or progression following aromatase inhibitors. But everolimus efficacy as late treatment has not been explored. Methods: Sixty-three MBC patients progressing under hormonotherapy (HT; n = 30) or after chemotherapy (CT; n = 32) received everolimus plus HT (EHT) and were analyzed for safety, efficacy and overall survival (OS). This cohort was compared with our previous 530 MBC patients stratified by line (PMID 21852136). Results: The median duration of EHT was 27.8 weeks at 5-10 mg/day until clinical progression or toxicity. Median OS was not reached (median follow-up 18 months). Twelve-month survival was 100, 79 and 49% for patients treated with 0 (n = 13), 1-2 (n = 18) and >3 CT (n = 32), respectively. Median time-to-treatment failure was 6.4 months. In 62 EHT patients randomly matched 1:7 with 421 previous patients for age and number of CT, OS improved compared with patients receiving a new CT (p = 0.062). In patients pretreated with <2 CT, EHT gave a better OS than in those with a new CT (p = 0.026). Conclusions: These results may support the use of EHT whatever the number of previous lines.
Endotoxin Tolerance Inhibits Lyn and c-Src Phosphorylation and Association with Toll-Like Receptor 4 but Increases Expression and Activity of Protein Phosphatases
Authors: Xiong Yanbao , Murphy Michael , Manavalan Tissa T. , Pattabiraman Goutham , Qiu Fu , Chang Hui-Hsin , Ho I-Cheng , Medvedev Andrei E.
Published: October 2015

Endotoxin tolerance protects the host by limiting excessive 'cytokine storm' during sepsis, but compromises the ability to counteract infections in septic shock survivors. It reprograms Toll-like receptor (TLR) 4 responses by attenuating the expression of proinflammatory cytokines without suppressing anti-inflammatory and antimicrobial mediators, but the mechanisms of reprogramming remain unclear. In this study, we demonstrate that the induction of endotoxin tolerance in human monocytes, THP-1 and MonoMac-6 cells inhibited lipopolysaccharide (LPS)-mediated phosphorylation of Lyn, c-Src and their recruitment to TLR4, but increased total protein phosphatase (PP) activity and the expression of protein tyrosine phosphatase (PTP) 1B, PP2A, PTP nonreceptor type (PTPN) 22 and mitogen-activated protein kinase phosphatase (MKP)-1. Chemical PP inhibitors, okadaic acid, dephostatin and cantharidic acid markedly decreased or completely abolished LPS tolerance, indicating the importance of phosphatases in endotoxin tolerization. Overexpression of PTPN22 decreased LPS-mediated nuclear factor (NF)-κB activation, p38 phosphorylation and CXCL8 gene expression, while PTPN22 ablation upregulated LPS-induced p65 NF-κB and p38 phosphorylation and the expression of TNF-a and pro-IL-1ß mRNA, indicating PTPN22 as an inhibitor of TLR4 signaling. Thus, LPS tolerance interferes with TLR4 signaling by inhibiting Lyn and c-Src phosphorylation and their recruitment to TLR4, while increasing the phosphatase activity and expression of PP2A, PTPN22, PTP1B and MKP1.
Recursos tecnológicos de apoio ao ensino na saúde
Authors: Peres Cristiane Martins , Suzuki Kátia Mitiko Firmino , Azevedo-Marques Paulo Mazzoncini de
Published: October 2015

A inserção das Tecnologias da Informação e Comunicação (TICs) no universo da atenção à saúde tem conduzido a mudanças de métodos de ensino e de processos na assistência, gerando também novos conceitos, com destaque para o de eSaúde. No início do século XXI um conjunto de inciativas para apoio ao uso das TICs nos diversos contextos da área da saúde passa a ganhar corpo no Brasil, tendo como destaques, o Telessaúde Brasil Redes, UNA-SUS (Universidade Aberta do SUS) e RUTE (Rede Universitária de Telemedicina). O foco desses programas se concentra no aperfeiçoamento contínuo dos profissionais com finalidades de atualização, capacitação técnica, cursos de aperfeiçoamento e discussão de casos clínicos na área da saúde. O movimento da utilização das TICs também tem progredido em direção a melhoria do processo de ensino e aprendizagem nos cursos de graduação, contudo ainda de forma limitada. Os recursos online e modelos de EAD que podem ser utilizados são muitos. Mas, ainda que várias instituições os ofereçam, há todo um entrono de planejamento educacional que precisa ser considerado. O papel da docência nesse contexto deve ser bem definido, para que as competências específicas para potencializar possíveis sucessos na utilização das TICs sejam desenvolvidas pelos docentes. Em uma análise com perspectiva institucional, evidencia-se a necessidade de estruturação de núcleos multiprofissionais como forma de apoio ao estudo, modelagem e implantação de estratégias e de programas que promovam uma utilização mais efetiva das TICs no cenário das ciências da saúde.
A Metodologia da Problematização (MP) como estratégia de integração ensino-serviço em cursos de graduação na área da saúde
Authors: Vieira Marta Neves Campanelli Marçal , Panúncio-Pinto Maria Paula
Published: October 2015

A formação de profissionais para atuar na área da saúde deve superar o modelo tradicional de educação centrado no paradigma cartesiano/flexneriano, fixado na fragmentação e especialização do conhecimento. A graduação em saúde precisa alcançar estratégias de ensino-aprendizagem que possibilitem a construção coletiva dos conhecimentos, a permanente integração teoria-prática referenciada na realidade social concreta. Tomando a perspectiva das metodologias ativas de ensino-aprendizagem, o objetivo deste artigo é apresentar e discutir a Metodologia da Problematização (MP) como estratégia políticopedagógica de aproximação à realidade e construção da autonomia na formação de profissionais da saúde. Além disso, apresenta as diferenças entre a MP a utilização de outras formas de problematização e solução de problemas como estratégia de ensino. Finalmente discute os limites e possibilidades do método.
Novos cenários de ensino: a comunidade e o território como espaços privilegiados de formação de profissionais da saúde
Authors: Panúncio-Pinto Maria Paula , Rodrigues Maria de Lourdes Veronese , Fiorati Regina Célia
Published: October 2015

A necessidade de ampliar os cenários de ensino para a formação de profissionais da saúde emergiu a partir da segunda metade do século passado, do processo histórico que resultou em mudanças tanto na organização dos sistemas de saúde de diversos países, quanto na forma de pensar o ensino e a formação de profissionais para atuar na atenção à saúde. Este artigo tem os objetivos de apresentar alguns resultados de discussões ocorridas em conferências e reuniões, nas áreas de Saúde e de Educação; os aspectos sociais, políticos e administrativos da assistência a saúde; as ações conjuntas dos Ministérios da Saúde e da Educação no Brasil para consolidação das políticas de formação de recursos humanos. Pontos de destaque na compreensão da emergência de novos cenários de ensino para profissionais da saúde remetem à adequação de currículos às necessidades sociais e de saúde dos países e regiões; à aproximação ensino-serviço na formação dos profissionais de saúde; à intersetorialidade e à multidisciplinaridade, além do reconhecimento da pertinência do ensino na comunidade para a aquisição de conhecimento, competências e habilidades. As autoras comentam, ainda, sobre barreiras para o desenvolvimento do ensino na comunidade, tanto da parte de membros da universidade quanto dos serviços de saúde, e sobre a importância do “novo cenário” de ensinagem para a integração das atividades-fim da Universidade e para o desempenho do papel social das Escolas das Profissões da Saúde.
Integração curricular: um desafio para os cursos de graduação da área da Saúde
Authors: Iglésias Alessandro Giraldes , Bollela Valdes Roberto
Published: October 2015

Com a expansão da educação superior, em especial na área da saúde, tem havido uma forte demanda para a formação de professores e gestores educacionais para os cursos superiores desta área no Brasil. Além disto, existe a real necessidade de formação de profissionais da saúde competentes para a o exercício profissional, reflexivos e cientes de suas responsabilidades junto a sociedade brasileira. Dentre as várias recomendações existentes para uma adequada organização curricular dos cursos da saúde, uma que se destaca de forma fundamental é a integração curricular das disciplinas, áreas e ciclos profissionais. Todos sabemos que a prática profissional acontece de maneira integrada, porém ainda é muito frequente observarmos cursos inteiros de graduação em que os estudantes aprendem de maneira fragmentada em unidades de ensino isoladas. Esse artigo pretende, de forma sintética e didática, apresentar aos docentes e estudantes interessados em educação e planejamento curricular dos cursos da área da saúde conceitos e estratégias eficazes para viabilizar propostas de ensino integrado na saúde.
Capacitação e desenvolvimento docente - aspectos gerais
Authors: López Maria José , Troncon Luiz E. A.
Published: October 2015

A atuação docente no ensino superior na área da saúde requer que o professor, além da expertise na sua disciplina, tenha também preparo na área educacional. Este preparo fundamental pode ser obtido em programas específicos de capacitação e deve ser mantido e aperfeiçoado em atividades de desenvolvimento docente. Os programas de capacitação e desenvolvimento docente são o objeto deste texto, de caráter introdutório, que trata dos atributos necessários ao bom professor, no desempenho dos vários papéis e funções que dele se espera, e das características de forma e conteúdo desejáveis nos programas de capacitação e desenvolvimento docente. Aborda-se, ainda, como estas atividades podem ser avaliadas visando o seu aperfeiçoamento constante e as dificuldades e desafios que habitualmente enfrentam. Apresentam-se, também, breves descrições de atividades de capacitação e desenvolvimento docente realizadas na Faculdad de Ciencias Medicas da Universidad Nacional de Cuyo, em Mendoza, Argentina, e na Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo, em Ribeirão Preto, Estado de São Paulo, Brasil.
Influência do treinamento concorrente na composição corporal e óssea de adolescentes obesos
Authors: Monteiro Paula A , Antunes Barbara de M M , Silveira Loreana S , Agostinete Ricardo R , Picolo Malena R , Freitas Junior Ismael F
Published: October 2015

Modelo de estudo: Estudo prospectivo Objetivo: Analisar a diferença da densidade, conteúdo mineral ósseo e composição corporal de adolescentes obesos pré e pós treinamento concorrente de 16 semanas. Métodos: Amostra composta por 19 adolescentes obesos. Mensurou-se a densidade mineral óssea(BMD), conteúdo mineral ósseo(BMC), massa corporal magra(MCM) em kg, massa de gordura(MG) em kg e em percentual(%GC) e percentual de gordura do tronco(%GT) por meio da técnica absortiometria de raios-X de dupla energia(DEXA). A Intervenção consistiu de treinamento concorrente (treino resistido [30 minutos] e aeróbio [30 minutos]) com três sessões semanais. Para análise estatística utilizou-se teste t de Student, qui-quadrado, ANOVA e correlação de Pearson por meio do software SPSS(17.0) e significância estatística fixada em p<5%. Resultados: Houve diferença estatística entre os gêneros para %GT(p<0,007). No grupo feminino houve correlação entre BMD, %GC e %GT, já a BMC correlacionou-se com peso e MCM. No grupo masculinohouve correlação da BMC e BMD com a estatura e MCM. Após a intervenção, no grupo feminino, houve significância apenas para estatura(p<0,014), já no grupo masculino houve aumento significativo daestatura(p<0,000), MCM(p<0,011) e BMC(p<0,002) bem como a diminuição das variáveis IMC(p<0,004), %GC(p<0,000) e %GT(p<0,016). Após o treinamento 78,9% dos adolescentes aumentaram e 21,1%diminuíram o BMD. Dos que aumentaram o BMD 63,2% diminuíram o %GC, 57,9% a MG e 57,9% a MCM. Conclusão: Após a intervenção houve diminuição da gordura corporal, aumento da massa magra e conteúdo mineral ósseo de adolescentes do sexo masculino. No grupo feminino não houve diferença entre os momentos.
Variability of size at maturity of the warrior swimming crab, Callinectes bellicosus (Stimpson, 1859) (Brachyura, Portunidae), along a latitudinal gradient in the Gulf of California
Authors: Rodríguez-Félix Demetrio , Cisneros-Mata Miguel Á. , Aragón-Noriega E. Alberto
Published: October 2015

For the warrior swimming crab,Callinectes bellicosus(Stimpson, 1859), we determined how size at maturity is affected by sea surface temperature along a latitudinal gradient. Samples came from the east side coast of the Gulf of California. Data of carapace width ofC. bellicosuswere collected monthly in 2012-2013 from commercial catches in three areas: northern, central, and southern. Average temperature increases from north (23.06°C) to south (25.4°C), and carapace width increases from north (106 mm) to south (117 mm). Size at maturity for males and females was directly related to temperature and inversely related to latitude, in contrast to rock crabs and shrimps in the Gulf of California and other regions. Plausible explanations and implications forC. bellicosusfishing are offered.