bluuebunny/crossref_metadata_2025 huggingface dataset:
In Silico Studies of Phytoconstituents to Identify Potential Inhibitors for ERα Protein of Breast Cancer
Authors: Alagarsamy Veerachamy , Sulthana Mohaideen Thasthagir , Narendhar Bandi , Solomon Viswas Raja , Parthiban Periyasamy , Satishchandra Aithamraju , Jothi Lalkote Aruna , Murugesan Sankaranarayanan
Published: September 2024

Background:

It is noteworthy that a wide array of plants and nutraceuticals are effectively
utilized in the treatment of various cancers, demonstrating potent effects on different cancer
targets with fewer side effects. Notably, estrogen alpha has been identified as a crucial factor in
breast cancer cell proliferation. Agents that can antagonize its action hold promise as potential drug
leads for the treatment of breast cancer.

Objective:

This study aims to discover and identify the potential inhibitors against the most influential
ERα receptor by the computational approach of 134 phytochemicals from 17 medicinal plants
by using in silico docking studies.

Methods:

The molecular docking was performed by a genetic algorithm using the Auto Dock Vina
program, and the validation of docking was also performed by using Molecular Dynamic (MD)
simulation by the Desmond tool of Schrödinger molecular modeling. Drug-likeness properties and
toxicity studies were conducted using SWISS PRO.

Results:

The top ten highest binding energy phytochemicals ginicidin (-10.8 kcal/mol), lemairone
(-10.5 kcal/mol), ixoratannin (-10.0 kcal/mol), hydnocarpine (-9.8 kcal/mol), arabelline (-9.8
kcal/mol), acutilobine E (-9.8 kcal/mol), chaparinone (-8.9 kcal/mol), plumieride coumerate (-8.8
kcal/mol), acutilobine C (-8.7 kcal/mol), and mezerein (-8.7 kcal/mol) were taken for drug-likeness
test and ADMET profile prediction with the help of web-based server SWISS ADME and protoxII.
Docking's study dictated that ten phytochemical constituents showed greater binding interactions
than standard tamoxifen (-6.6 kcal/mol) towards the target protein ERα. MSD study was achieved
for the most active 4 phytoconstituents, and the stability of the ligand-protein complex was confirmed
and showed that all the four compounds possess comparatively stable ligand-protein complexes
with ERα target as compared to the tamoxifen-ERα complex.

Conclusion:

Among the top ten phytochemicals, ginicidin (glycoside) formed a more stable complex
and had greater binding affinity than standard tamoxifen with better safety profiles. Hence,
this compound can be further studied for lead optimization and drug development for the treatment
of breast cancer.
Molecular Clusters and Hydrogen Storage by Clusters of Alkaline Earth Metal Oxides
Authors: Srivastava Ambrish Kumar , Srivastava Ruby
Published: September 2024

This chapter is exclusively devoted to molecular clusters. Molecular clusters
refer to finite aggregates of molecules or compounds. In such clusters, molecules are
usually bound by hydrogen bonding, van der Waals, or similar weak interactions. We
have shown some examples of molecular clusters, such as the clusters of H2O and LiF
molecules. Alkaline-earth metal oxide clusters such as (BeO)N
, (MgO)N
, and (CaO)N
have specifically been discussed, and their hydrogen storage behavior have been
explored using various DFT methods such as B3LYP, PBE-D3, M06-2X, etc. B3LYP
is a hybrid functional. PBE-D3 is a dispersion-corrected GGA functional, whereas
M06-2X is a meta GGA functional, as discussed in Chapter 1. It was found that small
(BeO)N
clusters prefer planar structures due to partially covalent Be-O bonds, unlike
ionic Mg-O and Ca-O bonds. Although all these clusters can effectively adsorb H2
molecules, smaller clusters serve as better adsorbents due to the high percentage mass
ratio.
Pengaruh Social Media Influencer Dan Brand Image Terhadap Purchasing Decision
Authors: Ramadhana Muhammad Raihan , Pradana Bayu Ilham
Published: September 2024

This research aims to determine the effect of social media influencer and brand image on purchasing decision Case study Instagram’s followers @kahfeveryday. This type of research is a quantitative research that aims to find a causal relationship between social media influencer, brand image, and purchasing decision. This research using 100 respondents as the sample from instagram’s followers @kahfeveryday. Sampling used a non-probability sampling technique, namely purposive sampling. The characteristic of the respondents must be over 17 years old, ever bought a Kahf product, and have seen instagram post of @kahfeveryday minimum 1 time. The data analytic in this research is using Multiple Linear Regression which supported by Validity Test, Reliability Test, and Classical Assumption Test. Hypothesis Test in this research was carried out using F-Test and t-Test using software SPSS 26. The result of this research are variable social media influencer and brand image had a significant effect on purchasing decision.
 
Abstrak
Penelitian ini bertujuan untuk mengetahui pengaruh social media influencer dan brand image terhadap purchasing decision pada followers Instagram @kahfeveryday. Jenis penelitian ini adalah penelitian kuantitatif dengan tujuan mengetahui hubungan sebab akibat antara variabel social media influencer, brand image, dan purchasing decision. Penelitian ini menggunakan sampel sebanyak 100 responden yang diambil dari followers Instagram @kahfeveryday. Pengambilan sampel menggunakan Teknik non-probability sampling yaitu purposive sampling. Karakteristik sampel yang di pilih yaitu berusia lebih dari 17 tahun, pernah membeli produk dari Brand Kahf, dan pernah melihat postingan Instagram @kahfeveryday minimal 1 kali. Teknik analisis yang digunakan dalam penelitian ini adalah Regresi Linear Berganda yang didukung dengan Uji Validitas, Uji Reliabilitas dan Uji Asumsi Klasik. Uji hipotesis yang dilakukan dalam penelitian ini adalah Uji F dan Uji-t menggunakan software SPSS 26. Hasil penelitian menunjukkan bahwa variable social media influencer dan brand image berpengaruh signifikan terhadap purchasing decision.
The Influence of Motivation and Service Quality Towards Customer Satisfaction
Authors: Rafiqi Idham Ramdan
Published: September 2024

This study aims to determine the impact of motivation and service quality on the customer satisfaction of participants in the Jakarta Cheetahs After Hour program. The research adopts an explanatory approach employing a quantitative method. Non-probability sampling techniques, specifically the purposive sampling method, were utilized, and the sample comprised 200 respondents. The inclusion criteria for respondents were a minimum age of 17 years and current or past participation in the Jakarta Cheetahs After Hour program. Measurement of items in the questionnaire was conducted using the Likert scale, assigning scores from 1 to 5. The Statistical Package for the Social Sciences (SPSS) was employed for the validity test, reliability test, and classical assumption test. Data analysis techniques included the multiple linear regression test and the coefficient of determination test. Hypothesis testing in this study involved partial hypothesis testing. The findings of this study indicate that the variable of Motivation (X1) has a positive influence on Customer Satisfaction (Y). Additionally, Service Quality (X2) was found to significantly impact Customer Satisfaction (Y).
 
Abstrak
Penelitian ini bertujuan untuk mengetahui pengaruh motivasi dan kualitas pelayanan terhadap kepuasan pelanggan Partisipan Jakarta Cheetahs After Hour. Jenis penelitian ini merupakan explanatory research dengan metode kuantitatif. Penelitian ini menggunakan teknik nonprobability sampling dengan metode purposive sampling dan menggunakan sampel sebanyak 200 responden. Kriteria yang dibutuhkan responden dalam penelitian ini adalah berusia minimal 17 tahun dan pernah atau sedang mengikuti Jakarta Cheetahs After Hour. Pengukuran yang digunakan sebagai nilai item pertanyaan dalam kuesioner adalah Likert scale dengan skor 1-5. Penelitian ini menggunakan Statistical Package for the Social Sciences (SPSS) untuk melakukan uji validitas, uji reliabilitas, dan uji asumsi klasik. Sedangkan teknik analisis data yang digunakan dalam penelitian ini adalah uji regresi linier berganda dan uji koefisien determinasi. Uji hipotesis yang dilakukan dalam penelitian ini adalah uji hipotesis secara parsial. Temuan penelitian ini menunjukkan bahwa variabel Motivasi (X1) berpengaruh positif terhadap Kepuasan Pelanggan (Y), sedangkan Kualitas Pelayanan (X2) berpengaruh signifikan terhadap Kepuasan Pelanggan (Y).
Caracterización estructural de fragmentos de Podocarpus oleifolius en bosques remanentes del suroccidente colombiano
Authors: López Duymovic Camilo José , Perdomo Hurtado Farid Ernesto , Marín Vélez Adriana María , Ramírez Correa Jorge Andrés
Published: September 2024

Las áreas de bosque altoandino en Colombia se han reducido considerablemente, por lo que especies ecológicamente relevantes como Podocarpus oleifolius presentan una disminución considerable en sus poblaciones y han sido categorizadas en estado vulnerable a la extinción (VU). Con el fin de caracterizar la demografía de tres de las únicas poblaciones remanentes de la especie en el suroccidente colombiano, se realizó un censo de las poblaciones donde se evaluó la densidad poblacional, la estructura y la distribución espacial de los tres fragmentos de bosques considerados dentro de un gradiente de intervención y en un área de potrero. La distribución espacial de las poblaciones se evaluó mediante análisis bivariados, mientras que la influencia de las variables fisiográficas sobre la distribución de las especies se evaluó mediante un análisis de componentes principales. Se encontró que la población de P. oleifolius presenta una estructura diamétrica unimodal en varios de los fragmentos, tiene una proporción mayor de hembras que de machos, una baja densidad poblacional y una distribución espacial en agregados. Ello señala la reducción de las posibilidades de polinización de la especie y las características fenotípicas de los individuos. Los fragmentos remanentes de la especie requieren su conservación y un manejo urgente para evitar la desaparición de esta importante especie a largo plazo.
MEASURING THE DIFFERENCE BETWEEN TEACHING AND NON-TEACHING ANESTHESIA STAFF WORKLOAD at AL-NOOR SPECIALIST HOSPITAL, MAKKAH, SAUDI ARABIA, MARCH 2021 (Preprint)
Authors: Ali Shammah Ahmed
Published: September 2024

BACKGROUND

Workload on health sector workers has increased dramatically in recent years. In this research we studied anesthesia staff in terms of teaching and non-teaching workload at AL Noor Specialist hospital and the extent of its impact on performance and vigilance. Decreased workload improves the performance and vigilance of anesthesia staff.

OBJECTIVE

1. To determine the difference between the workload of teaching and non-teaching anesthesia staff.
2. To measure the workload of anesthesia staff in teaching and non-teaching cases.
3. To identify the definition, component, and effect of workload.
4. To explain the importance of the work of anesthesia staff.

METHODS

This is a cross-sectional study carried out using a Google form survey conducted among anesthesia staff at Al-Noor specialist Hospital, Makkah, Saudi Arabia. The target of the study included anesthesia staff (Anesthesia Technologist, Anesthesia Specialist, Anesthesia Consultant).

RESULTS

The workload density graph shows that the induction period in teaching cases was slightly higher compared to non-teaching cases. during the maintenance period and recovery period, workload density was slightly higher in teaching cases compared to the induction period.
The degree of agreement with the statement, “stress and pressure increase during surgery (teaching cases)”, was mostly in the normal range.
The degree of agreement with the statement, “increased workload will reduce your performance level and vigilance during the surgery”, was mostly in the strongly agree range.
The degree of agreement with the statement, “increasing the workload reduces patient safety”, was mostly in the strongly agree range.

CONCLUSIONS

There is only a slight difference in workload between teaching and non-teaching cases, but this slight change may stand between the life or death of a patient in an area of fine margins, such as anesthesia. We recommend further study to include all hospitals in Makkah. We recommend that difficult cases, especially patients with American Society of Anesthesiologists(ASA3) or above, do not have students because that may jeopardize the safety of the patient and inhibit the vigilance and performance of anesthesia providers.
Community engaged approach to increase physical activity among Black individuals with colorectal cancer: Design of the Physical Activity Centers Empowerment (PACE) feasibility randomized controlled trial (Preprint)
Authors: Hirschey Rachel , Xu Jingle , Woodard Nathaniel , Duggins Paulette , Lea Deirdre F. , Milner John L , Coleman Jr Karia , Bryant Ashley Leak , Sanoff Hanna K , Triglianos Tammy , Zou Baiming , Burse Natasha Renee , Hoover Rebecca L , Leeman Jennifer , Wheeler Stephanie B , Battaglini Claudio L , Valle Carmina G
Published: September 2024

BACKGROUND

Black individuals are more likely to die from colorectal cancer (CRC) and experience more treatment-related side effects compared to White individuals. Physical activity (PA) participation has been associated with decreased side effects, improved CRC treatment completion rates and responses, and survival. However, Black CRC survivors are 60% less likely to participate in PA than White survivors. The Physical Activity Centers Empowerment (PACE) study is testing an intervention specifically designed to increase PA among Black individuals diagnosed with CRC.

OBJECTIVE

This paper outlines the protocol for a randomized controlled trial (RCT). The study aims to test the feasibility of PACE; using the RE-AIM framework, reach, effectiveness, adoption, implementation, and maintenance will be measured.

METHODS

The PACE study was developed in partnership with a community advisory board consisting of Black cancer advocates and survivors. The study aims to recruit seventy-two participants over 18 years old who have been diagnosed with CRC from North Carolina. These participants will be randomized in a 1:1 ratio to an intervention or control group. During the 12-week intervention, all participants will receive a wearable activity tracker and informational materials from the American College of Sports Medicine's “Moving through Cancer” program. The intervention group will also receive additional PACE theory-guided intervention components, including personalized daily adaptive step goals, access to the PACE video library, and optional video chat meetings for PA support. Data will be collected at three points - baseline, post-intervention (3 months), and six months post-intervention (9 months). Using the RE-AIM framework, the study aims to evaluate the intervention's reach, effectiveness, acceptability, implementation, and maintenance.

RESULTS

The National Institute on Minority Health and Health Disparities funded this study in 2021. Study enrollment began in August 2024 and is anticipated to conclude in December 2024.

CONCLUSIONS

This study will advance our understanding of effective behavioral strategies to increase PA participation and help advance the utilization of PA as a form of complementary cancer treatment, with the aim of improving health outcomes for Black CRC survivors.

CLINICALTRIAL

This trial is registered on clinical.trials.gov (NCT06411756).
User Engagement in Digital Health Applications: Scoping Review. (Preprint)
Authors: Aktas Melek , Cambon Linda , Aromatario Olivier
Published: September 2024

BACKGROUND

Participation has moved from political protest to active engagement in various areas, including health. Patient engagement has transformed healthcare, and mHealth has positioned mobile technology as a tool for health promotion. Research indicated that user engagement is crucial for effective mHealth interventions.

OBJECTIVE

This paper aims to explore the attributes, methods and barriers to user engagement in mHealth.

METHODS

For this scoping review, a systematic approach was used to map the evidence on mHealth interventions for health promotion and prevention, following PRISMA-ScR guidelines. Scopus, Web of Science and PubMed databases were searched using tailored keywords. A two-stage selection process was implemented, focusing on participation attributes, methods, and barriers/facilitators.

RESULTS

The study analyzed mHealth interventions for health promotion and prevention. Out of 1,533 articles identified, 782 were screened and 41 met the inclusion criteria for analysis. Participation definitions and attributes varied by discipline and author, with scales and gradations qualifying participation by intensity or within the mHealth. User engagement methods included theory-based interventions, behavior change techniques, user-centered design, personalization, autonomy, peer support, motivation and gamification. Challenges included barriers to technology adoption, lack of theory-based interventions, personalization, autonomy, peer support, motivation and gamification.

CONCLUSIONS

The understanding of user participation in digital interventions is complex and diverse, lacking consensus. Definitions vary among intervention providers, reflecting distinct objectives and methodologies. The absence of clear concepts and attributes highlights the need to refine definitions in digital health, which is essential for guiding intervention evaluation and development methodologies.
The Power of Social Media Influencer Campaigns to Improve Black Women’s Knowledge and Awareness of Environmental Endocrine Disrupting Chemicals: Surveys of Instagram Users (Preprint)
Authors: Franklin Elissia T. , Boronow Katherine E. , Liss Ohayon Jennifer , Momplaisir Aleyana , Steele Jenell , Smith Camille Kathleen , Taylor LaShannon , Brock Breanna D. , Grayson Korie A. , Edgecombe Kalere , Harris Brittany S. , Pender Kristen N. , Kola Ijeoma B , Llanos Adana A. M. , Teteh-Brooks Dede K. , Marcelin Lilly , Green Brody Julia , Dodson Robin E.
Published: September 2024

BACKGROUND

Black women are disproportionately affected by hormone-related health conditions, which may result from higher exposures to endocrine disrupting chemicals (EDCs) in consumer products. EDCs are chemicals that interfere with the body’s natural hormones.

OBJECTIVE

The Product Options in Women-Engaged Research (POWER) project was developed to educate Black women about EDCs. We assessed the impact of social media influencer (SMI) campaigns on knowledge and awareness of EDCs and intentions to change product-use behaviors.

METHODS

We recruited seven SMIs to engage with their audiences about EDC-related information on Instagram. The SMIs attended a workshop to learn about EDCs in consumer products and then created Instagram content to share with their audiences. We surveyed SMIs at baseline and 1-month after they shared EDC-related content. SMI audiences were surveyed cross-sectionally before and after the SMIs posted EDC-related social media content. We evaluated social media engagement and analyzed the impact of the campaign on SMIs and their audience.

RESULTS

The social media posts reached over 16,000 accounts and elicited over 28,000 engagements (e.g., views, likes, shares). SMIs’ EDC knowledge and awareness increased after attending the workshop and sharing newly created content, and the SMIs had greater intentions to avoid EDCs at follow-up than at baseline. Engagement with the social media content about EDCs also led to positive outcomes among SMI audiences, and particularly impacted intentions to engage in exposure reduction behaviors. Eighty percent of follow-up survey respondents reported that they will always consider a company’s chemical policy and product ingredients when shopping compared to less than 50% of baseline survey respondents (P<.001), and more follow-up respondents than baseline respondents self-reported an intention to avoid parabens (33% vs 15%, P<.001), bisphenol A (25% vs 15%, P=.032), per- and polyfluoroalkyl substances (17% vs 9%, P<.001), and fragrance (5.9% vs 2.0%, P=.082).

CONCLUSIONS

Our findings demonstrate researcher-SMI collaborations can be employed to reach large audiences of Black women, improve knowledge about EDCs, and promote intentions to change behaviors to reduce exposures to EDCs.
Developing a Framework for Online Review-based Healthcare Service Quality Assessment: A Text-Mining Study (Preprint)
Authors: Zhang Xue , Sun Jianshan , Li Xin , Liu Yezheng , Li Chenwei
Published: September 2024

BACKGROUND

The assessment of medical service quality is difficult, due to the information asymmetry between patients and doctors. With the development of online healthcare platforms, patients nowadays have more channels to reach medical service and assess others reviews as a quality indicator. However, what aspects in online reviews we should care that may affect the demand of doctors remain largely unexplored.

OBJECTIVE

The goal of this study is to establish a more comprehensive medical service quality evaluation system that reflect patients' actual experience and satisfaction from a broader perspective and provide a more scientific basis for improving the quality of medical services.

METHODS

We adopt a text mining approach, conducting topic analysis, theory-driven topic selection, and aggregation to develop a five-dimensional healthcare service quality framework based on online reviews. This framework encompasses doctors' expertise, communication attitude, service delivery process, service outcomes, and empathy. We also conduct empirical analysis to assess if the patients’ positive or negative assessment (i.e., sentiments) on the dimensions would matter to the future demand. The heterogeneity caused by disease type and doctors rank are explored as well.

RESULTS

Using data from a large online healthcare platform in China, we find that the polarity of patient opinions on the five dimensions significantly affect the patient demand. We also show patients suffering from chronic diseases are more sensitive to these dimensions comparing with patients suffering from non-chronic diseases. Doctors’ rank also exhibit significant moderating role among 5 dimensions.

CONCLUSIONS

This study offers a foundational exploration of how patients prioritize online reviews when evaluating healthcare services, with significant implications for healthcare management. Our findings provide both clinicians and patients with practical insights for delivering high-quality healthcare services. The results can guide doctors and healthcare managers in formulating strategies to enhance service quality, minimize patient dissatisfaction, and strengthen patient-provider relationships.
Behavior Emotion Therapy System and You (BETSY): Co-design and Evaluation among Healthy Participants of a Mental Health Chatbot and Digital Human for Mild to Moderate Anxiety (Preprint)
Authors: Thunström Almira , Ali Lilas , Krage Carlsen Hanne , Bohm Maria , Wesén Linda , Wrede Olof , Sarajlic Vukovic Iris , Hellström Andreas , Larson Tomas , Steinngrimsson Steinn
Published: September 2024

BACKGROUND

Co-design is a collaborative approach involving end users, stakeholders, and designers in creating digital tools for healthcare. This study focuses on the co-design and evaluation of Behavior Emotion Therapy System and You (BETSY), a mental health chatbot and digital human for mild to moderate anxiety.

OBJECTIVE

To develop and evaluate BETSY through a co-design process involving potential users.

METHODS

The study employed a mixed-methods approach across three phases. Phase 1 involved recruiting 87 volunteer participants through social media for initial end-user requirements. Phase 2 focused on the design process based on end-user requirements employing the expertise of 10 stakeholders in healthcare and health service user. Phase 3 evaluated of the two prototyped interfaces (text-only chatbot and voice-interactive digital human chatbot) through 45 healthy volunteers.

RESULTS

For phase 1, 60.7% of participants had previous experience with chatbots and 85.7% expressed a willingness or potential willingness to use a chatbot for mental health support. Thematic analysis in phase 2 revealed key user preferences for a personalized, non-judgmental chatbot with a clear identity and focus on empathy. Privacy concerns and the need for clear interaction guidelines were highlighted. In phase 3, the users showed a strong preference for discussing anxiety related to work, relationships, and health. Both text-only and voice-interactive digital human users considered BETSY valuable for managing mild to moderate anxiety and providing self-help exercises.

CONCLUSIONS

The co-design process yielded valuable insights for developing BETSY. While users recognized its potential as an accessible first step before seeking professional help, they also identified areas for improvement, including more nuanced conversation capabilities and a broader range of exercises. BETSY's potential as a screening tool for healthcare was consistently acknowledged, suggesting its capability for alleviation of healthcare system burdens.

CLINICALTRIAL

No trial registration
Nghiên cứu giải pháp xây dựng kè ứng phó nguy cơ sạt lở bờ biển Hiệp Thạnh, thị xã Duyên Hải, tỉnh Trà Vinh
Authors: Văn Hữu Huệ , Lê Văn Tuấn
Published: September 2024

Mục đích nghiên cứu là tìm ra nguyên nhân sạt lở và đề xuất giải pháp ứng phó sạt lở bờ biển Hiệp Thạnh, thị xã Duyên Hải, tỉnh Trà Vinh. Phương pháp nghiên cứu là khảo sát, đánh giá địa chất, tác động do sóng biển, vận chuyển bùn cát thông qua các phần mềm Mike 21, Plaxis, Geoslope và đưa ra kết quả nghiên cứu. Kết quả cho thấy nguyên nhân chủ yếu gây sạt lở là do sóng lớn tác động vào bờ biển vào mùa gió chướng, làm bùn cát bị xới tung, dòng chảy ven bờ mang bùn cát đi làm cho bờ biển bị hạ thấp gây sạt lở… Qua đó, một số giải pháp công trình và hướng nghiên cứu mới cho khu vực nghiên cứu được đưa ra nhằm đảm bảo an sinh cho bà con trong khu vực nghiên cứu.
Ước lượng tham số mô hình hồi quy logistic với hiệp biến thiếu dữ liệu ngẫu nhiên và ứng dụng
Authors: Trần Phước Lộc , Tạ Thị Thanh Thúy , Dương Thị Tuyền , Dương Thị Bé Ba , Lê Hoài Nhân , Lâm Hoàng Chương
Published: September 2024

Nghiên cứu đề xuất phương pháp ước lượng hệ số của mô hình hồi quy logistic với hiệp biến thiếu dữ liệu ngẫu nhiên. Trước tiên, phương pháp thay thế lặp được sử dụng để thay thế các giá trị thiếu bằng các giá trị hợp lý thu được từ hàm phân phối thực nghiệm có điều kiện. Ước lượng các tham số của mô hình hồi quy và phương sai của nó sau đó thu được lần lượt bằng các phương trình ước lượng và phương sai tương ứng. Các tính chất cỡ mẫu lớn của ước lượng cũng được nghiên cứu. Hiệu quả tính toán của phương pháp đề xuất được nghiên cứu thông qua một số tình huống mô phỏng số và so sánh với các phương pháp khác. Kết quả cho thấy phương pháp đề xuất có hiệu quả tốt hơn các phương pháp xóa hàng, trọng số xác suất nghịch đảo bán tham số, hợp lý có điều kiện và thay thế lặp bằng phương pháp rừng ngẫu nhiên. Dữ liệu thực tế về y học được sử dụng để minh họa khả năng ứng dụng của phương pháp đề xuất.
Mô phỏng xác suất có điều kiện bằng phần mềm R
Authors: Bùi Anh Kiệt , Trịnh Phùng Chí
Published: September 2024

Xác suất có điều kiện là một nội dung mới được bổ sung vào lớp 12 trong Chương trình Giáo dục phổ thông môn Toán 2018. Đây là một khái niệm hoàn toàn mới đối với học sinh phổ thông, đòi hỏi giáo viên phải có sự chuẩn bị kĩ về kế hoạch dạy học, phương pháp giảng dạy và phương tiện giảng dạy. Bài viết trình bày việc sử dụng mô phỏng trong giải bài toán Xác suất có điều kiện, đề xuất quy trình sử dụng phần mềm R trong giải bài toán Xác suất có điều kiện.
Ảnh hưởng của tỷ lệ phối chế và điều kiện thanh trùng đến chất lượng sản phẩm nước uống từ thịt quả mãng cầu xiêm (Annona muricata L.)
Authors: Huỳnh Thị Ngọc Mi , Đoàn Thị Kiều Tiên
Published: September 2024

Mãng cầu xiêm (Annona muricata L.) là một trong những loại trái cây nhiệt đới có tiềm năng trong sản xuất nước ép, necta, jam, thịt quả đông lạnh và bột mãng cầu xiêm mang lại hiệu quả kinh tế cao. Mục đích của nghiên cứu là khảo sát sự ảnh hưởng của tỷ lệ phối chế và điều kiện thanh trùng đến chất lượng cảm quan sản phẩm. Nghiên cứu được thực hiện với tỷ lệ pha loãng giữa puree và nước (1:2, 1:2,5, 1:3 và 1:3,5) theo khối lượng, hàm lượng đường (TSS ) bổ sung vào (16, 18 và 20 °Brix), giá trị pH (3,3, 3,6 và 3,9) và điều kiện thanh trùng sản phẩm sau cùng (75, 80 và 85°C theo thời gian tương ứng lần lượt là 5, 10 và 15 phút). Kết quả cho thấy điều kiện phù hợp được lựa chọn để chế biến nước uống từ thịt mãng cầu xiêm là 18 °Brix, pH 3,6 và tỷ lệ pha loãng theo khối lượng với 1 puree mãng cầu xiêm và 3 nước, thanh trùng sản phẩm sau cùng ở nhiệt độ 80°C trong 10 phút. Sản phẩm được tạo ra đạt theo tiêu chuẩn của Bộ Y tế QCVN 6-2:2010/BYT với hàm lượng axít tổng là 0,24% và hàm lượng vitamin C là 1,47 mg%.
Kiểm toán nội bộ khu vực công – tổng kết một số chủ đề và đề xuất hướng nghiên cứu
Authors: Lê Phước Hương , Vũ Xuân Nam , Trần Khánh Dung
Published: September 2024

Mục tiêu của bài viết là tìm hiểu sự phát triển của kiểm toán nội bộ khu vực công, xác định các trọng tâm nghiên cứu và đề xuất các hướng nghiên cứu trong tương lai. Bài viết lượt khảo 77 bài báo khoa học để thảo luận nguồn dữ liệu, khung lý thuyết, đối tượng cung cấp thông tin, phương pháp nghiên cứu và đánh giá kết quả nghiên cứu. Các nghiên cứu tiếp theo được đề xuất là tập trung vào so sánh nhiều quốc gia, bổ sung lý thuyết nền, bằng chứng thực nghiệm liên quan đến quản lý rủi ro và chi tiêu lãng phí, việc tiếp thu các kỹ năng công nghệ thông tin cho kiểm toán viên, xem xét tác động của các đặc điểm văn hóa, thể chế, nhân khẩu học và thiết kế các mô hình chặt chẽ để dự đoán hiệu quả kiểm toán nội bộ khu vực công.
Ảnh hưởng của bao trái tiền thu hoạch đến chất lượng trái vú sữa tím (Chrysophyllum cainito L.) tại huyện Kế Sách, tỉnh Sóc Trăng
Authors: Nguyễn Thị Thuở , Nguyễn Thị Bích Hằng , Vũ Bá Quan , Trần Văn Toàn , Vũ Quan , Lê Trung Tâm
Published: September 2024

Thí nghiệm được thực hiện nhằm đánh giá loại túi bao trái và thời điểm bao trái trước thu hoạch phù hợp để giảm thiểu thấp nhất tỉ lệ ruồi đục trái mà vẫn đảm bảo năng suất và chất lượng trái vú sữa tím. Thí nghiệm được bố trí theo thể thức khối hoàn toàn ngẫu nhiên, hai nhân tố: (1) là loại vật liệu túi bao trái (nilon trong, vải xốp, túi kết hợp nilon trong và vải xốp), đối chứng không bao trái và (2) là thời điểm bao trái (90 ngày, 120 ngày và 150 ngày sau đậu trái). Thí nghiệm được thực hiện trên vườn vú sữa tím 7 năm tuổi tại 2 xã Trinh Phú và Xuân Hòa (huyện Kế Sách, tỉnh Sóc Trăng). Kết quả cho thấy, việc sử dụng túi bao trái trước thu hoạch đã giảm thiệt hại do ruồi đục trái hơn 96%. Vật liệu túi nilon trong là phù hợp để bao trái vú sữa tím do tỉ lệ ruồi đục trái thấp (khoảng 3,3%), khối lượng trái cao (235 g), độ Brix cao (14,1). Thời điểm bao trái phù hợp là 90 ngày sau đậu trái.
Nghiên cứu thành phần tuyến trùng ký sinh thực vật trên cây đậu phộng (Arachis hypogaea) tại tỉnh Trà Vinh
Authors: Nguyễn Gia Huy , Nguyễn Thị Thu Nga , Trần Vũ Phến , Nguyễn Văn Hòa
Published: September 2024

Thành phần tuyến trùng ký sinh thực vật (PPNs) liên quan đến cây đậu phộng được thực hiện tại các huyện Duyên Hải, Cầu Ngang và Trà Cú, tỉnh Trà Vinh. Phương pháp nghiên cứu dựa vào đặc điểm hình thái học và các chỉ số đo về hình thái lượng kết hợp một số chỉ số đánh giá đặc điểm sinh học quần xã trong đất. Kết quả khảo sát đã ghi nhận được 17 loài, 10 giống PPNs thuộc 8 họ bao gồm: Pratylenchus coffeae, P. brachyurus, Ditylenchus ausafi, Helicotylenchus crenacauda, Hirschmanniella oryzae, H. mucronata, Mesocriconema curvatum, M. ornatum, Mesocriconema sp., Meloidogyne graminicola, Tylenchorhynchus leviterminalis, T. mashhoodi, T. nudus, T. annulatus, Tylenchus sp., Longidorus elongatus và Xiphinema elongatum. Trong đó, tần suất hiện diện của giống Mesocriconema phổ biến trên nhóm đất cát chiếm 100% và đã ghi nhận sự xuất hiện của 3 giống Pratylenchus, Tylenchorhynchus và Hirschmanniella trong rễ cây đậu phộng; đồng thời đã ghi nhận sự hiện diện của giống tuyến trùng Pratylenchus phổ biến trong trái đậu phộng có triệu chứng đốm đen. Hai giống Mesocriconema và Pratylenchus tìm thấy trong nghiên cứu này là tác nhân ký sinh quan trọng trên cây đậu phộng và cần tiến hành các biện pháp phòng trừ.
Implementasi Standard Operating Procedure Resepsionis Dalam Melakukan Check-In dan Check-Out
Authors: Sintyawati Ni Wayan , Suwintari I Gusti Ayu Eka
Published: September 2024

Penelitian ini dilakukan pada bagian Front Office Department. Studi ini dilakukukan untuk mengetahui bagaimana implementasi standard operating procedure resepsionis dalam melakukan check-in dan check-out di Amandari Resort Ubud. Penelitian ini dilatar belakangi karena masih didapati tamu yang kebingungan dengan informasi mengenai hotel yang seharusnya sudah mereka ketahui setelah melakukan proses check-in. Dan juga sering didapati barang tamu yang ketinggalan pada saat melakukan proses check-out. Alat ukur yang digunakan untuk mengetahui bagaimana implementasi standard operating procedure resepsionis dalam melakukan check-in dan check-out adalah dengan melakukan observasi dan wawancara. Wawancara ini dilakukan langsung dengan Ibu Agung Asrami selaku Front Office Supervisor di Amandari Resort Ubud. Data yang digunakan pada penelitian ini adalah data kualitatif, data yang tidak berupa angka tetapi data yang berupa keterangan. Hasil dari penelitian ini menyatakan bahwa implementasi standard operating procedure sudah diterapkan dengan cukup baik, namun terdapat beberapa prosedur yang jarang diterapkan dikarenakan keterbatas waktu dan juga selalu menyesuaikan dengan kedaan dan juga kondisi dilapangan.
 
This research was conducted in the Front Office Department. This study was conducted to determine how the implementation of receptionist standard operating procedures in checking in and check-out at Amandari Resort Ubud. This research is motivated because there are still guests who are confused with information about the hotel that they should have known after the check-in process. And also often found guest items that are missed during the check-out process. The measuring tool used to determine how the implementation of the receptionist's standard operating procedure in checking in and check-out is by observing and interviewing. This interview was conducted directly with Ibu Agung Asrami as Front Office Supervisor at Amandari Resort Ubud. The data used in this study is qualitative data, data that is not in the form of numbers but data in the form of information. The results of this study show that the implementation of standard operating procedures has been implemented quite well, but there are some procedures that are rarely applied due to time constraints and also adjust to the situation and also conditions in the field.
Thought after the Revolution: the Aporia of the Grounds
Authors: Bogatov Mikhail
Published: September 2024

The purpose of the article is to consider a unique situation of theoretical thought after the revolution. If the revolutionary formulation of the previously considered "natural" grounds turned out to be productive for natural sciences, humanitarian thinking faced a number of fundamental aporias. In the article these aporias are explicated and author gives their sequential description. The author introduces the concept of two levels of law. The first level of the law approves the very order of any authority, the second level provides an opportunity for lawmaking. The retention of first level of the law affords a basis for thought. The revolutionary situation denies the necessity of first-level laws and seeks to establish itself in the second-level laws in various ways. One such way is to imitate the existence of the first level of laws. Another way is a constant, increasingly accelerating, law-making. The third way is to take control of the time itself so that the question of grounds is no longer raised. All these ways complement each other. The author considers the consequences of their application for thought that has appeared in the situation after the revolution. He refers to several historical examples, touching upon the issue of Germany's acquiring its identity through the discovery of its own antiquity and through the reflection of Saint-Just. As a result, the author raises the question of the status of modernity, which determines the way of current thought.
The norm of Political moral: the intellectual project of Antonio Gramsci
Authors: Savino Giovann
Published: September 2024

In the present paper we analyze the formation and the development of Antonio Gramsci, Italian Marxist theoretician, ideas during and after the 1917 Russian revolution. Beginning as journalist and militant in the Italian Socialist Party Turin branch, Gramsci saw in the revolutionary events in Russia the presence of the working class' "strength”, as the main actor in transforming the society in a "collective body”. After 1917, during the "Biennio rosso” in 1919-1920, Gramsci was the chief redactor of "Ordine Nuovo” review, from which appealed to the Italian workers to follow the Bolshevik experience, emphasizing their "spiritual strength”. Then, during his days jailed as political prisoner by Fascists, the Communist leader reflected on the concepts of "hegemony”, "passive revolution”, and on the role of the intellectuals into the society.
What Should We Do with Neuroscience? From the Epistemology of Suspicion to an Epistemology of Care
Authors: Filatova Asya
Published: September 2024

Today, neuroscience is undoubtedly at the focus of close public attention and interest. It is associated with the greatest hopes, but also arouses the innermost fears. Neuroscience has become a challenge not only for practical fields such as medicine or pharmacology but for all of the human sciences. Representatives of leading trends in social sciences and humanities have entered the discussion about the possible benefits and threats related to the rapid growth of knowledge in neuroscience. The neuro-turn has become a conceptual framework in which the neuro-centric style of thinking sets the regimen of truth. The article presents a cartography of the space of epistemological solutions proposed by social theory and philosophy in response to the active expansion of neuroscience. Above all, the article explicates the internal mechanics of the critical program - which is based on the logic of "strong explanation" - symmetrically implemented both by critical social theory and neuroscientists. Within the framework of post-critical approaches making a case for replacing the logic of exposure with other epistemological strategies, alternatives to "barbaric criticism" in sociology and philosophy are proposed. In particular, we consider Wittgensteinian sociology which implements a methodology of clarification of the conceptual confusions that arise in neuroscience studies, as well as B. Latour's actor-network theory and K. Barad's agential realism proposing to abandon, on principled grounds, basic binary oppositions such as culture/nature, social/biological, and cerebral/symbolic in favour of the notions of "network" and "onto-epistemological entanglement".
Neuropsychoanalysis and Its Conceptual Problems
Authors: Uzlaner Dmitry
Published: September 2024

This article is devoted to a critical analysis of neuropsychoanalysis, an interdisciplinary field that emerged at the end of the 20th century and set itself the task of combining neuroscience with the psychoanalytic approach. The author draws attention to the conceptual gaps of this ambitious undertaking. The main gap is argued to be the insufficient attention paid to the psychophysical problem (or mind-body problem), which ends up overlooking the fundamental difference between brain and psychic / mental reality, and attempts to derive the principles of functioning of the latter from the observations of brain activity. This, in turn, leads to further problems: the problem of translation and search for a correspondence between psychoanalytic theory based on a thick observation of the subject's mental activity and the conceptual tools of neurosciences. What percentage of loss of meaning in this translation can be recognized as acceptable and what remains of psychoanalysis as a result of such a procedure? Another problem is related to the intersubjective symbolic nature of human desire, which cannot be deduced from observations of brain physiology. Finally, the author draws attention to the fact that neurosciences - and neuropsychoanalysis is no exception here - are already initially interwoven into social and cultural space, making them easy victims of contemporary- sometimes implicit - ideological attitudes. The article concludes with a call for greater reflexivity regarding neuropsychoanalysis on the part of both interested parties - psychoanalysts and neuroscientists.
Studies of expertise and experience as a way to overcome the crisis of expert knowledge: The problem of philosophical foundations
Authors: Kalinin Vladislav
Published: September 2024

The focus of the article is the project of British sociologists H. Collins and R. Evans on the Study of Expertise and Experience (SEE). The author of this article attempts to explicate the contexts of talking about expertise as a sociopolitical phenomenon. On the one hand, expertise is discussed in one line of research as an important component of socio-political processes. Expertise is defined in terms of power, its ability to influence decision-making processes in a legitimising way is increasing. On the other hand, the socio-ontological status of expertise is leveled due to the democratisation of access to information and the divergence of the modes of co-existence of science and politics, which is why, according to the researchers, expertise is in crisis. In these contexts, the author turns to the SEE project, which seeks to address the side effects of the proliferation of constructivist sociologies of knowledge and science. By questioning the ability of groups to access the truth and formulate expert judgements on its behalf, constructivist sociology removed the expert as a bearer of specified knowledge from the intellectual scene. Collins and Evans put expertise back on the research agenda; they propose a normative typology of expertise. The author of the article reconstructs the logic of constructing classifications of expertise and problematising two of its key types - interactional and contributory expertise. The article describes in detail the philosophical assumptions behind the concept of interactional expertise. The claims of this concept - as the author of the project sees it - to describe not only a common type of expertise, but also to become one of the conceptual resources for describing society are questionable, due to linguistic reductionism. Collins and Evans reproduce classic problems of sociological theory within the primary distinction of types of expertise.
PENGARUH E-KUALITAS LAYANAN DAN PERSEPSI HARGA MEMEDIASI KEPUASAN PELANGGAN TERHADAP LOYALITAS KONSUMEN PADA E-COMMERCE LAZADA
Authors: Pujianti Anik , Sihite Janfry
Published: September 2024

This study aims to examine and analyze the effect of e-service quality and price perception mediating customer satisfaction on consumer loyalty in ecommerce Lazada. The population in this study is millennial and gen z people who make online transactions more or less 2 times a month. The number of samples used in this study were 125 respondents with a quantitative descriptive approach. Data analysis using Partial Least Square (PLS). This study proves that e-service quality has a positive and significant effect on customer satisfaction. Price perception has no positive and significant effect on customer satisfaction. E-service quality has a positive and significant effect on consumer loyalty. price perception has a positive and significant effect on consumer loyalty. Customer satisfaction has a positive and significant effect on consumer loyalty.
PENGARUH GREEN BRAND IMAGE, PACKAGING, DAN STORE ATMOSPHERE TERHADAP LOYALITAS PELANGGAN PRODUK THE BODY SHOP
Authors: Astuti Subekti Lidia , Imaningsih Erna Sofriana
Published: September 2024

The Body Shop juga merupakan pioneer perusahaan kosmetik internasional yang menghimbau terhadap standar kosmetik untuk manusia dengan memberantas uji coba terhadap binatang. Objek penelitian ini adalah pelanggan pada produk The Body Shop. Penelitian ini dilakukan terhadap 126 responden. Sampel yang digunakan adalah purposive sampling dalam salah satu metode non probability sampling. Jenis penelitian ini adalah analisis kausal dengan pendekatan kuantitatif. Sampel pada penelitian ini sebanyak 126 pelanggan. Teknik pengumpulan data dengan menggunakan kuesioner. Metode pengumpulan data menggunakan survey, dengan instrumen penelitian adalah kuesioner. Metode analisis data menggunakan alat analisis Partial Least Square (PLS). Penelitian ini membuktikan bahwa green brand image berpengaruh positif dan signifikan terhadap loyalitas pelanggan, packaging berpengaruh positif dan signifikan terhadap loyalitas pelanggan dan store atmosphere berpengaruh positif dan signifikan terhadap loyalitas pelanggan. Penelitian ini juga menjelaskan bahwa loyalitas pelanggan dipengaruhi model sebesar 69,9% sedangkan sisanya sebesar 55% dipengaruhi oleh variabel lain yang tidak diteliti dalam penelitian ini.
PENGARUH RASIO KEUANGAN TERHADAP FINANCIAL DISTRESS (Studi pada Perusahaan Sub Sektor Retail Trade yang Terdaftar di Bursa Efek Indonesia Tahun 2016-2020)
Authors: Rofiah Zakiatur , Juniarti Septiani
Published: September 2024

Penelitian ini bertujuan untuk mengetahui Pengaruh Current Ratio, Debt to Equity Ratio, Return On Asset, dan Sales Growth terhadap Financial Distress pada sub sektor Retail Trade yang terdaftar di Bursa Efek Indonesia periode 2016-2020. Populasi dalam penelitiam ini adalah 27 perusahaan. Teknik Pemilihan sampel dalam penelitian ini menggunakan metode purposive sampling dan didapatkan 8 perusahaan sebagai sampel yang memenuhi kriteria. Data penelitian diperoleh dari Bursa Efek Indonesia. Metode yang lebih tepat digunakan pada penelitian ini adalah Random Effect. Hasil penelitian ini menunjukan bahwa variabel Current Ratio memiliki pengaruh positif dan signifikan terhadap Financial Distress, Debt to Equity Ratio memiliki pengaruh positif namun tidak signifikan terhadap Financial Distress, Return On Asset yang memiliki pengaruh positif dan signifikan terhadap Financial Distress, dan Sales Growth memiliki pengaruh positif namun tidak signifikan terhadap Financial Distress.
Pengaruh Media Promosi Tiktok Dan Harga Terhadap Keputusan Pembelian Melalui Kepuasan Pelanggan Produk Di Tiktok Shop
Authors: Saputri Nur Puput , Maya Siska
Published: September 2024

Penelitian ini bertujuan untuk mengetahui dan menganalisa pengaruh media promosi TikTok dan Harga terhadap keputusan pembelian melalui kepuasan pelanggan produk di TikTok Shop.Populasi dalam penelitian ini adalah pengguna TikTok Shop di Jakarta Selatan, sedangkan sampel yang digunakan dalam penelitian ini adalah 97 responden. Pengambilan sampelmenggunakan rumus Lemeshow, sedangkan pengumpulan data dilakukan dengan menggunakan kuesioner melalui gform. Dari pengolahan data menggunakan aplikasi SmartPLS versi 4 didapat (1) Media promosi TikTok berpengaruh positif dan signifikan terhadap Keputusan Pembelian, (2) Harga berpengaruh positif terhadap keputusan pembelian, (3) Media promosi dan harga berpengaruh terhadap kepuasan pelanggan,(4) Media promosi tidak berpengaruh positif terhadap kepuasan pelanggan, (5) Harga berpengaruh terhadap Kepuasan Pelanggan, (6) Kepuasan pelanggan berpengaruh positif terhadap kepuasan pelanggan, (7) Kepuasan Pelanggan berpengaruh terhadap Keputusan Pembelian, (7) Media promosi berpengaruh terhadap Keputusan Pembelian yang dimediasi oleh Kepuasan Pelanggan, (8) Harga berpengaruh terhadap Keputusan Pembelian yang dimediasi oleh Kepuasan Pelanggan.