bluuebunny/crossref_metadata_2025 huggingface dataset:
Democracia, Cultura e Convergência
Authors: Alkimim Rocha Filho Ruy
Published: May 2022

O artigo apresenta um panorama histórico focalizando a regulamentação da Radiodifusão e posteriormente da Internet no Brasil, entre 1910 e 2010. Ao colocar em perspectiva as leis referentes ao Rádio e à TV, observamos as contradições do cenário político brasileiro e os problemas relativos a metas de qualidade e universalização, bem como à concentração de propriedade e à falta de critérios democráticos para distribuições de concessões e de financiamento. A somadesses fatores cria obstáculos para a consolidação da democracia no país, afetando o papel do Estado e o enfrentamento de problemas sociais seculares.
Disputas Hegemônicas nos Movimentos de Junho de 2013
Authors: Girotto Neto Angelo
Published: May 2022

O presente artigo tem como objetivo analisar os marcos ideológicos das disputas hegemônicas que envolvem os protestos de junho de 2013, tendo como agentes analisados os grupos sociais que disputaram sua orientação política. Parte-se de uma revisão bibliográfica completada por documentos da época para defender a hipótese de que durante os eventos de 2013 dois campos políticos – um representado pelas forças aliadas ao governo petista de Dilma Rousseff; outro pela oposição conservadora capitaneada pela mídia constituída em partido nos termos gramscianos – disputaram os sentidos das manifestações, gerando um impasse político que culminou no abandono temporário das ruas pelas principais forças políticas do país.
Populismo e Fundamentalismo na Atuação Política dos Evangélicos
Authors: Pimentel Lopes Júnior Orivaldo
Published: May 2022

Entrevista com Marcelo Natividade
Perspectivas em gestão da Informação e do conhecimento no contexto das bibliotecas
Authors: Farias Gabriela Belmont de , Fernandes Júlio César Pinto
Published: May 2022

Apresenta a análise da temática gestão da informação e do conhecimento no contexto das bibliotecas. Buscou-se identificar quais abordagens e autores da área da gestão da informação e do conhecimento são recorrentes, bem como identificar quais as metodologias são mais utilizadas. A pesquisa é de caráter exploratório, de cunho bibliométrico e de característica quantiqualitativa. Quanto ao procedimento foi realizada uma coleta de dados nos anais do Encontro Nacional de Pesquisa e Pós-graduação em Ciência da Informação, no período de 2005 a 2019, especificamente os trabalhos publicados no GT4 que trata da Gestão da Informação e Gestão do Conhecimento. Os resultados evidenciam que a maioria das temáticas nos trabalhos analisados que envolvem Gestão da Informação e do Conhecimento no âmbito das bibliotecas estão relacionados aos serviços específicos das bibliotecas, como serviço de referência, e plano de diagnósticos, sendo, portanto, em sua maioria estudos de caso, bem como o referencial teórico que apoia tais pesquisas são de áreas que envolvem a administração e a ciência da informação.
Ópera fashion em Manaus
Authors: Vlaxio Felipe , França Elionilde Rodrigues de
Published: May 2022

O artigo propõe uma base teórico-semiótica para representação descritiva e temática de figurinos de ópera. Trata-se de uma pesquisa vinculada a um projeto institucional desenvolvido na Universidade Federal do Amazonas para criação de um Catálogo Virtual da Ópera Manauara. Tem como objetivo a elaboração de uma ferramenta de representação descritiva e temática para figurinos de ópera. A pesquisa utiliza-se da semiótica da cultura para embasamento teórico da ferramenta proposta. A ficha elaborada foi aplicada a um total de 48 espetáculos de ópera e quatro musicais realizados entre os anos de 1997 e 2011 por ocasião do Festival Amazonas de Ópera. Espera-se, desta feita, contribuir para o resgate e manutenção do patrimônio artístico e cultural da cidade de Manaus, de modo a proporcionar sua recuperabilidade em sistemas de informação.
Casa de Farinha do Povoado Terreirão, Muniz Ferreira, Bahia
Authors: Santos Eva Dayane Jesus dos , Miranda Zeny Duarte de
Published: May 2022

Este trabalho é resultado parcial da produção da dissertação sobre a informação e a memória social da Casa de Farinha no povoado Terreirão em Muniz Ferreira, Bahia. Logo, este trabalho se justifica por possibilitar a ampliação do conhecimento sobre as trajetórias e narrativas afro-indígenas, e pela compreensão de que há uma necessidade científica na área, de ampliar o entendimento a respeito de comunidades étnicas-raciais, uma vez que é necessário o combate contra o racismo estrutural, institucional e científico que tem produzido esquecimentos e apagamentos sobre essas histórias. Outrossim, nosso problema é saber: Quais elementos informacionais podemos identificar na Casa de Farinha, considerando as influências étnico-raciais (indígenas e africanas)? Assim, o objetivo geral é identificar os elementos informacionais do lugar, através da Casa de Farinha. Os objetivos específicos são: registrar as narrativas sobre a origem do Povoado Terreirão; apresentar os elementos informacionais desenvolvidos na Casa de Farinha do Povoado Terreirão; relatar a formação territorial do lugar no contexto do Recôncavo Baiano e do município de Muniz Ferreira; e apontar as informações documentais sobre o lugar. A metodologia utilizada é de abordagem descritiva e qualitativa. Utilizou-se métodos da etnometodologia, da pesquisa exploratória e do estudo de caso. As técnicas e procedimentos adotados foram: visita de campo, diário de campo, entrevistas, observação direta e participante, pesquisa bibliográfica e documental. Tem como resultados parciais as narrativas sobre a formação territorial do lugar e a apresentação dos elementos informacionais que representam a informação étnico-raciais observados in loco.
Redes de coautoria da produção científica brasileira na área de células-tronco
Authors: Machado Raymundo das Neves , Lima Gillian Leandro de Queiroga
Published: May 2022

Este trabalho tem por objetivo analisar a rede de coautoria da produção científica brasileira na área de células-tronco, no período de 2001 a 2020. Trata-se de uma pesquisa de caráter longitudinal, de natureza quantitativa e descritiva, pautada na análise de redes sociais, tendo a coocorrência de autores como unidade de medida e, unidade de análise, o autor citante. Os resultados apresentam as métricas de produção científica e as redes referentes ao maior componente de cada rede de coautoria, dos quatro subperíodos analisados: 2001-2005, 2006-2010, 2011-2015 e 2016-2020. Por fim, infere-se que a crescente produção de estudos na área de células-tronco, no Brasil, e o aumento da rede de coautoria nos períodos analisados foram alavancados em virtude do aumento do número de autores e das ações promovidas pelo Ministério da Saúde, em parceria com o Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq). Como perspectivas futuras de análise, este trabalho pretende identificar os autores mais relevantes, as áreas e assuntos predominantes de estudo e a evolução temporal das pesquisas em células-tronco no Brasil.
Relato e historia en el Camino Real de Tierra Adentro
Authors: Ferro Vidal Luis Enrique
Published: May 2022

Desde la academia histórica se suele desdeñar los relatos históricos de la memoria considerándolos como apócrifos o poco confiables de veracidad. Sin embargo, no se puede negar que cada historia contada por los historiadores y cada relato narrado en la tradición mantienen un eje principal que le da coherencia a la trama del acontecimiento. Ambas formas de contar una misma historia nacen de un hecho o proceso del pasado que se convierte en discurso. Es así que en este artículo se propone establecer que ninguna forma de historia debe desdeñarse, sino que se intenta mostrar que los relatos de la memoria, como un texto abierto, deben comprenderse dentro de contextos narrativos históricos, y demostrar, en consecuencia, que existe un paralelismo entre ambas formas de evocar una misma historia, para así determinar que la historia oral, en ocasiones, no es tan apócrifa como se suele pensar. El elemento de análisis es un relato de fundación de un pueblo guanajuatense que se centra en el contexto de la historia del Camino Real de Tierra Adentro.
Insight into the Synthesis, Biological Activity, and Structure-activity Relationship
of Benzothiazole and Benzothiazole-hydrazone Derivatives:
A Comprehensive Review
Authors: Kumar Rajnish , Singh Himanshu , Yadav Ranjeet Kumar , Mazumder Avijit , Salahuddin  , Chauhan Bharti , Abdullah Mohd. Mustaqeem
Published: May 2022

Heterocyclic compounds constitute the most important part of medicinal as well as organic
chemistry. Most of the marketed drugs possess therapeutic activity because of the presence
of heterocyclic scaffolds as part of their structure. A slight change in the structure of the heterocyclic
moieties may result in a major change in the therapeutic response of the drug candidate.
Among all heterocycle compounds, the compounds containing nitrogen and sulfur atoms serve as
a unique resource for drug development, such as benzothiazoles. Benzothiazole is a benzofused
heterocyclic that is widely reported as a constituent of naturally occurring chemicals and chiefly
responsible for their pharmacological potential. It was also reported that the pharmacological activity
of BTA may also be influenced by its coupling with aldehydes, ketones, or hydrazines to
form respected benzothiazole-hydrazone derivatives. The present comprehensive review consists
of various synthesis methods, biological activities, and structure-activity relationships of and targets
of benzothiazole and benzothiazole-hydrazone derivatives to provide a wide range of information
to medicinal chemists for future research work.
Plant Secondary Metabolites as Apoptosis-inducing Agents
Authors: Faridi Uzma
Published: May 2022

Apoptosis or programmed cell death is a carefully synchronized collapse of cells due to protein degradation, fragmentation of DNA. It is an essential part of the life cycle of every multicellular organism including worms to humans. Apoptosis plays a major role in cancer development as well. Various studies confirm the potential of many drugs to change the regulation and ratio of proapoptotic and antiapoptotic factors. Plants are the best-known source of drugs for various kinds of diseases including cancer. Plant secondary metabolites (alkaloids, terpenes and phenolics) are the major constituents used as drugs. Several studies confirm that these secondary metabolites can induce apoptosis by triggering proapoptotic and antiapoptotic factors. In this article, some of the important secondary metabolites and their mode of action as apoptotic triggering agents have been studied.
Green Synthesized Nanoparticles as a Plausible Therapeutic Strategy
Against Hepatocellular Carcinoma: An Update on its Preclinical and
Clinical Relevance
Authors: Chandrababu Gopika , Sah Sunil Kumar , Kumar Ayana R. , M Sabitha , Nath Lekshmi R.
Published: May 2022

Green nanotechnology can offer notable advantages over the conventional drug delivery methods in terms of improved drug stability, drug-carrying capacity, site-specificity, and feasibility to apply different routes of administration with less systemic toxicities. Metal nanoparticles bio fab-ricated with phytoconstituents and microbial extracts have gained significant interest for the treatment of various solid tumors including hepatocellular carcinoma. Hepatocellular carcinoma (HCC) is an aggressive cancer with a very poor prognosis. The current treatments of HCC fails to provide tumor specificity, causing many systemic toxicities and poor overall survival benefits especially for patients in advanced and terminal stages. A novel therapeutic approach with maximal therapeutic effect and minimum adverse effects are urgently required for HCC patients. Green synthesized metal nanopar-ticles offer significant anticancer effects along with minimal systemic toxicities because of their site-specific delivery into the tumor microenvironment (TME). Green synthesized metal nanoparticles can therefore be a highly beneficial strategy for the treatment of HCC if properly validated with pre-clinical and clinical studies. This review focuses on the preclinical evidence of the most widely stud-ied green metal nanoparticles such as green synthesized silver nanoparticles, gold nanoparticles and selenium nanoparticles. We have also summarised the clinical studies and the patents approved for nanoparticles against HCC.
Boosting Anti-tumour Immunity Using Adjuvant Apigenin
Authors: Xiao Chuli , Najafi Masoud , Huang Jun , Chen Xuedong , Chang Zaoshang
Published: May 2022

The interactions and secretions within the tumour have a pivotal role in tumour growth and therapy. Immunosuppressive cells such as regulatory T cells (Tregs), myeloid-derived suppressor cells (MDSCs), tumour-associated macrophages (TAMs), and cancer-associated fibroblasts (CAFs) secrets some substances, which can result in exhaustion of anti-tumour immunity. To stimulate anti-tumour immunity, suppression of the secretion and interactions of immunosuppressive cells, on the other hand, stimulation of proliferation and activation of natural killer (NK) cells and CD8+ T lymphocytes are required. Apigenin is a flavone with anticancer properties. Emerging evidence shows that not only does apigenin modulate cell death pathways in cancer cells but it also can stimulate anti-tumour immune cells to release death signals and suppress the release of tumour-promoting molecules. In this review, we discuss the interactions between apigenin and various cells within the tumour microenvironment (TME). These interactions may enhance anti-tumour immunity to improve the efficiency of anticancer remedies such as immunotherapy.
Erectile Dysfunction in Patients with Multiple Chronic Conditions: A Cross-
Sectional Study
Authors: Giagulli Vito Angelo , Lisco Giuseppe , Bartolomeo Nicola , Ramunni Maria Isabella , De Tullio Anna , Carbone Matteo Domenico , Guastamcchia Edoardo , De Pergola Giovanni , Triggiani Vincenzo
Published: May 2022

Background:

The prevalence of erectile dysfunction (ED) rises with the number and severity of chronic diseases.
Study aims. This cross-sectional study assessed the frequency and severity of ED in patients with multiple chronic conditions.

Study aims:

This cross-sectional study assessed the frequency and severity of ED in patients with multiple chronic conditions.

Methods:

The 5-item International Index of Erectile Function questionnaire (IIEF-5) to diagnose and classify ED. The Charlson Comorbidity Index (CCI) was used to assess the burden of chronic comorbidity. The primary outcome was to assess the ED frequency according to CCI severity. The secondary outcomes included the assessment of correlation between 1) IIEF-5 and total testosterone (TT), 2) CCI and TT, 3) IIEF-5 and CCI. Lastly, the CCI and modified CCI (mCCI) performance were compared with each other.

Results:

The overall frequency of ED increased along with the CCI score severity: 45% for CCI=0; 95% for CCI=1; 91% for CCI=2; 99% for CCI≥3 (p<.0001). CCI correlated negatively with TT levels and IIEF-5 score (r=-0.34 and -0.44; p<.0001). Compared to the CCI, a novel proposed mCCI performs well.

Discussion:

The frequency and severity of ED are relevant in outpatients with sexual complaints and those with chronic comorbidities. Despite limitations, mCCI may be considered a reliable tool to assess the overall burden of multiple chronic conditions in patients with comorbidities.

Conclusion:

ED is a reliable proxy of overall male health. Further studies are needed to confirm this potential application.
What do we know about Toll-Like Receptors Involvement in Gout Arthritis?
Authors: Silva Cássia Regina , Saraiva André Lopes , Rossato Mateus Fortes , Trevisan Gabriela , Oliveira Sara Marchesan
Published: May 2022

Toll-like receptors (TLRs) are a well-characterized family of cell-bound pattern recognition receptors able to identify and respond to conserved structures of external microorganisms or Pathogen Molecular-Associated Pattern (PAMPs). They can also interact with Damage-Associated Molecular Patterns (DAMPs) involved with any infectious and sterile cell stress of tissue injury. Accumulated knowledge about TLRs has revealed that these receptors and intracellular signaling pathways triggered through TLR activation contribute to the physiopathology of different inflammatory diseases, including arthritic conditions. Mostly, the literature focuses on exploring TLRs in rheumatoid and osteoarthritis. However, TLRs also seem to be an essential mediator for monosodium urate (MSU) crystals-induced gouty arthritis, both in animal models and humans. Accordingly, naked MSU crystals have a highly negatively charged surface recognized by TLRs; intracellular adapter protein MyD88 are significant mediators of MSU crystals-induced IL1β production in mice, and gouty patients demonstrate a robust positive correlation between TLR4 mRNA level and serum IL1β. Here, we revised the literature evidence regarding the involvement of TLRs in gout arthritis pathogenesis, with particular reference to TLR2 and TLR4, by analyzing the actual literature data.
Emerging Nanovaccine Technology: Defense Against Infection by Oral
Administration
Authors: Dewangan Hitesh Kumar , Raghuvanshi Akash , Shah Kamal
Published: May 2022

Oral vaccines have been proposed as a potential vaccine against a variety of infections, particularly invading pathogens throughout the GIT. Oral vaccinations targeting the large intestine could be a viable alternative to intracorneal immunizations which have been shown to be effective against rectogenital infections but are impractical during mass vaccination. Furthermore, the oral route allows for the development of humoral and cellular immune responses in both systemic and mucosal locations, resulting in a larger and longer-lasting protective effect. Oral administration, on the other hand, is difficult, needing formulations to overcome the harsh GI efficiency and reduce tolerance induction to obtain adequate protection. This review article will highlight the mode of action of oral vaccines, the list of license oral vaccine, type of vaccines, and the physiological barriers and immunological barriers to oral transport of peptides and proteins.
Nanostructured Lipid Carriers: New Insight for Cancer Therapy
Authors: Jiwankar Manasi , Sabale Vidya
Published: May 2022

Cancer is a life-threatening disease that is associated with persistent tissue injury and uncontrolled cell growth. The treatments available to treat cancer include chemotherapy, surgery, and radiation therapy. These treatments are utilized in combination while the most preferred treatment is chemotherapy. Because of the non-specificity of anticancer drugs, they kill healthy cells along with cancer cells, which lead to severe side effects. To minimize such limitations associated with conventional chemotherapy, nanostructured lipids carriers (NLCs) can be developed. These are the nanocarriers consisting of a mixture of solid and liquid lipids and surfactants. Lipids utilized in the formulation of NLCs are biocompatible and biodegradable. NLCs ensure high drug payload, less drug expulsion, and more stability on storage. NLCs enhance the aqueous solubility of lipophilic anticancer drugs. Their surface modification can help to overcome drug resistance in cancer therapy. Controlled and targeted drug delivery of anticancer drugs can be possible by formulating them as NLCs. NLCs can play an important role in targeting anticancer drugs by different mechanisms. This review highlights types, formulation methods, characterization of nanostructured lipid carriers, and strategies to achieve targeted release of anticancer drugs loaded in NLCs.
Snake Envenomation and Innate Immune System: An Overview
Authors: Reis Mouzarllem Barros , Cazeloto Anna Caroline Vendrame , Roque Julia Breda , Ferreira Juliana Cogo , Vigo Marianna Minaré , Zoccal Karina Furlani
Published: May 2022

Snake envenomations are one of the most common venomous accidents caused by animals in the world. The symptoms induced after bite vary accordingly to the species. Most of the snake venoms elicit direct or indirect activation of the innate immune responses that ranges from local to systemic effects and contributes to the clinical manifestations after envenoming. The venom interacts with the immune system by inducing the release of damage-associated molecular patterns, which contributes to create a proinflamatory status, release of cytokines and lipid mediators, and has properties to modulate other components of the innate immune system like the complement system. In this review, we highlitht some studies that point out over the years the mechanisms by which snake venoms interact with the innate immune system, as well as the pharmacological potential of this class of compounds with great applicability to the medical field.
Toxins from Venomous Arthropods in Brazil: Patents and Potential Biotechnological Applications
Authors: de Castro Pedro Henrique Cardoso , Paiva Ana Luiza Bittencourt , Oliveira-Mendes Barbara Bruna Ribeiro , Guerra-Duarte Clara , Matavel Alessandra
Published: May 2022

Background:

The diversity of components in arthropod venoms constitute a rich source of bioactive molecules. Brazil is the most biodiverse country of the world, comprising 15 to 20% of the total catalogued species, with approximately 103,870 animal species including arthropods. Although many articles mention the biotechnological potential of these venoms and toxins, only few studies compile the patented uses of these molecules.

Objective:

This review describes the knowledge about the molecular mechanism of venoms and toxins with biotechnological potential, and list the patents deposited up to 2021 related to the main medical relevant arthropods in Brazil including the orders Araneae (spider genus Phoneutria, Loxosceles, Latrodectus), Scorpiones (scorpion genus Tityus), Lepidoptera (caterpillar genus Lonomia), and Hymenoptera.

Methods:

The international patent search engine “Espacenet” and the “Brazilian patent office” were used to search the patents described in this article.

Results:

Up to date, 34 patents have been filled involving these Brazilian arthropods' venoms or toxins. Most of them (20) claimed biotechnological inventions with spider toxins, mainly from the genus Phoneutria. Only seven inventions involved venom or toxins from scorpions, one from bee, three from wasps, and three from caterpillars.

Conclusions:

Brazil is one of the main references in venoms and toxins’ studies; however, the limited number of deposited patents related to this area by Brazilian researchers do not reflect their pioneer position in this field. On the other hand, patents were well described and made with purified toxins, rather than with the whole venom. Nevertheless, the vast publication record of venom and toxin characterization that leads to a better understanding of their molecular mechanisms paves the way for turning these promising molecules into possible products.
HNT-Cellulose based Nano-Composite and Applications
Authors: Raman A.P.S.
Published: May 2022

Halloysite, a naturally occurring nanoclay has unique characteristics like nanometric size range, tubular structure, high biocompatibility, low cost and opposite charges on its surface is driving attraction as a versatile and important component of biomaterials. The incorporation of functionalized Halloysite nanotubes (HNT) with the cellulose biopolymer is to obtain enhanced and desirable properties like mechanical strength, and barrier properties and to have controlled pore size. The enhanced properties of bio-nano composites are employed in wide areas including food packaging, the automobile industry, drug delivery and many more. In this chapter, extended work on various HNT-cellulose-based bio- nanocomposites is provided along with their structural, and functional properties including their applications.
Montmorillonite-Cellulose based Nano-Composites and Applications
Authors: Baruah P.
Published: May 2022

Exploration of different types of polymer-clay nanocomposites have already crossed several decades. In recent times, more emphasis is given in the research of different bio-based polymer nanocomposites as they exhibit eco-friendly biodegradable behavior and biocompatible features. Cellulose is the most copiously available bio-macromolecule with interesting functional, chemical, mechanical and biological properties. Incorporation of montmorillonite clay as nanofillers into cellulose matrix results in significant modification and reinforcement in various properties of the polymer enlarging its applicability. This chapter brings forth a concise account on the development of different montmorillonite-cellulose based nano-composites as prospective materials for multiple biomedical and engineering applications.
Halloysite-Starch based Nano-Composites and Applications
Authors: Ahmed F.R.
Published: May 2022

Halloysite is a novel mineral belonging to the kaolinite family of clays. It consists of largely cylindrical particles in the size range of few hundred to few micrometers in length. The negatively charged Si-O-Si functional groups at the surface and positively charged Al2(OH)4 at the luminal side offer unique chemistry to this clay mineral. Biopolymers such as starch are considered biodegradable and non-toxic in nature. But their higher water permeability, poor mechanical strength, and rigid characteristics limit their applications in many fields. Halloysite and starch hybrid materials or composites have been demonstrated to improve on these properties and at the same time remain natural. They have a wide variety of applications such as tissue engineering, drug delivery and food packaging materials. Besides this, they have also been used as catalyst and flame retardant materials.
O Contencioso da União Europeia e a cobrança transfronteiriça de créditos: compreendendo as soluções digitais à luz do paradigma da Justiça eletrónica europeia (e-Justice) - Volume III
Authors: Joana Rita Sousa Covelo Abreu , Larissa Araújo Coelho , Tiago Sérgio Alves Cabral
Published: May 2022

Os textos publicados neste e-book, sob o tema “O Contencioso da União Europeia e a cobrança transfronteiriça de créditos: compreendendo as soluções digitais à luz do paradigma da Justiça Eletrónica europeia (e-Justice)” correspondem, na sua essência, ao suporte teórico da 3.ª Edição do Curso Intensivo, promovido sob a forma de Spring School, com o mesmo título, que ocorreu nos dias 14 a 18 de março de 2022, na Escola de Direito da Universidade do Minho, em formato online. A publicação desta obra corresponde a um dos objetivos visados no Módulo Jean Monnet com o acrónimo “eUjust” e subordinado ao tema “EU Procedure and credits’ claims: approaching electronic solutions under e-Justice paradigm”, desenvolvido, na Escola de Direito da Universidade do Minho, de setembro de 2019 a agosto de 2022, com a chancela da Comissão Europeia e do Programa ERASMUS+, que conta com a coordenação científica da Prof. Doutora Joana Covelo de Abreu, Professora da mesma instituição, e integrando, na sua equipa, a Prof. Doutora Alessandra Silveira e o Prof. Doutor Pedro Madeira Froufe. Neste contexto, o Módulo partiu da sensibilidade auscultada pela equipa que o integra de que, com o estabelecimento de um Mercado Único Digital, a União Europeia começou a votar uma atenção particular às dinâmicas associadas às novas tecnologias de informação e de comunicação ao serviço de uma boa administração da justiça. Na verdade, apesar de se verificarem esforços em equacionar, introdutoriamente, uma justiça eletrónica europeia, que datam, em termos formais, de 2007 (e com o arranque do primeiro Plano Plurianual de Ação, do Conselho, em 2009), a realidade é que esta ganhou novo fôlego e atualidade com a apresentação, em 2019, do Plano e da Estratégia do Conselho sobre justiça eletrónica europeia, a implementar até 2023. [...]
Fecundity and morphological description of the eggs of Psorophora cyanescens (Coquillett, 1902) (Diptera: Culicidae) by scanning electron microscopy
Authors: García-Rejón Julián E. , Tzuc-Dzul Julio C. , Cigarroa-Toledo Nohemi , Talavera-Aguilar Lourdes G. , Cetina-Trejo Rosa C. , Baak-Baak Carlos M.
Published: May 2022

Taxonomic studies on mosquitoes are based on the morphological description of larvae and adults. However, few studies have focused on the morphological description of eggs despite their taxonomic value. The description of mosquito eggs by scanning electron microscopy (SEM) allows more detailed descriptions of the ornamentation of the egg, which can provide diagnostic characters of the species. The objective of the work was to describe the eggs of Psorophora cyanescens by SEM and provide fecundity data for the species. In general, Ps. cyanescens eggs are elliptical and very wide. The exochorion is characterized by polygon pattern, where each polygon consists of longitudinal ridges joined by cross-ridges defining regular "hexagonal" areas. Each longitudinal ridge consisting by a small tubercle. The small tubercles are irregular, rectangular, rounded, or tubular. The ornamentation of the exochorion also has long and conical tubercles throughout the egg region. The micropylar apparatus located in the anterior region of the egg has a prominent, continuous and thickness collar. Psorophora cyanescens laid mature eggs at 2.5 days post-feeding. The mean number of eggs per female was 82.20 (± 13.31). This is the first study that describes the ultrastructure of the morphology of the eggs of Ps. cyanescens by SEM. With the contribution of the present work, there are five species of the genus Psorophora whose eggs morphology is described by SEM: Ps. albigenu, Ps. albipes, Ps. columbiae, Ps. cyanescens, and Ps. ferox.
Formation of Tax Revenues of Municipal Budgets: State and Prospects of Development
Authors:   Southwest State University, Tkacheva Tatyana Yu. , Belousova Svetlana N. , Rykunova Valentina L.
Published: May 2022

Relevance. Taxes are called, on the one hand, to form the financial resources of local self-government bodies, and on the other, to serve as an instrument of socio-economic policy of the municipality. In most foreign countries, municipal budgets are formed at the expense of tax revenues and are the basis of the country's economic security, in Russia they have become the most problematic link in the budget system. Purpose. The article is aimed at substantiating promising areas for increasing the tax potential of local budgets on the basis of a comprehensive study of the peculiarities of the formation of local budget revenues, an analytical-systematized approach, the existing regional fiscal practice. Tasks. The article solves the following tasks: an analysis and assessment of local budget revenues in the Russian Federation is carried out, factors influencing the formation of local budget revenues are reflected, and ways to increase tax revenues are considered. Objectives: analysis and assessment of local budget revenues of the Russian Federation, substantiation of promising areas for increasing the tax potential of local budgets on the basis of an analytical-systematized approach, existing regional fiscal practice. Methodology. The methodological base of the study is based on a systematic approach, within the framework of which the methods of logical, economic-statistical and dynamic analysis were used. Results. The article presents an analysis and assessment of local budget revenues of the Russian Federation, substantiates promising areas for increasing the tax potential of local budgets on the basis of an analytical-systematized approach, the existing regional budget and tax practice. It is concluded that the interdepartmental active work on the legalization of labor activity of foreign citizens, monitoring of employment in the informal sector of the economy, the level of wages at enterprises located in municipalities, the financial condition of city-forming and large enterprises will contribute to increasing tax revenues of municipal budgets. Conclusion. In recent years, most municipalities have faced common problems such as insufficient tax revenues and increased funds allocated from higher budgets. Given that a significant share in the tax revenues of municipal budgets of the Russian Federation is the tax on income of individuals, it is advisable for individual entrepreneurs whose professional tax deductions are more than 94% in the income received to introduce a minimum tax, which will greatly contribute to an increase in tax revenues of local budgets.
Design, Development, and Testing of BEST4Baby, an mHealth Technology to Support Exclusive Breastfeeding in India: Pilot Study
Authors: Ma Tony , Chang Katie , Alyusuf Amal , Bajracharya Elina , Washio Yukiko , Kelly Patricia J , Bellad Roopa M , Mahantashetti Niranjana S , Charantimath Umesh , Short Vanessa L , Lalakia Parth , Jaeger Frances , Goudar Shivaprasad , Derman Richard
Published: May 2022

Background

Exclusive breastfeeding (EBF) at 6 months of age in most low- and middle-income countries, including India, is surprisingly low. There is a relative lack of mobile health apps that specifically focus on leveraging the use of peer counselors (PCs) to support mothers as a means of increasing EBF practices in low- and middle-income countries.

Objective

This study aimed to design, develop, and test the usability of Breastfeeding Education Support Tool for Baby (BEST4Baby), a mobile health app specifically designed to support PCs in providing in-home breastfeeding counseling support to mothers in rural India on optimal breastfeeding practices.

Methods

A user-centered design process with an agile development methodology was used. The approach involved stakeholders and mothers who were trained to serve as PCs to guide BEST4Baby’s design and development, including the app’s content and features. PCs were engaged through focus groups with interactive wireframes. During the 24-month pilot study period, we conducted a feasibility test of the BEST4Baby app with 22 PCs who supported home visits with mothers residing in rural India. The intervention protocol required PCs to provide education and follow mothers using the BEST4Baby app, with 9 scheduled home visits from the late prenatal stage to 6 months post partum. BEST4Baby’s usability from the PCs’ perspective was assessed using the translated System Usability Scale (SUS).

Results

The findings of this study align with best practices in user-centered design (ie, understanding user experience, including context with iterative design with stakeholders) to address EBF barriers. This led to the cultural tailoring and contextual alignment of an evidence-based World Health Organization breastfeeding program with an iterative design and agile development of the BEST4Baby app. A total of 22 PCs tested and rated the BEST4Baby app as highly usable, with a mean SUS score of 85.3 (SD 9.1), placing it over the 95th percentile for SUS scores. The approach translated into a highly usable BEST4Baby app for use by PCs in breastfeeding counseling, which also statistically increased EBF practices.

Conclusions

The findings suggest that BEST4Baby was highly usable and accepted by mothers serving as PCs to support other mothers in their EBF practices and led to positive outcomes in the intervention group’s EBF rates. The pilot study demonstrated that using the specially designed BEST4Baby app was an important support tool for mothers to serve as PCs during the 9 home visits.

Trial Registration

Clinicaltrials.gov NCT03533725; https://clinicaltrials.gov/ct2/show/NCT03533725
Physicians’ Perspectives on Inpatient Portals: A Systematic Review (Preprint)
Authors: Banguilan Kaila Louise , Sonnenberg Frank , Chen Catherine
Published: May 2022

BACKGROUND

Inpatient portals are online platforms that provide patients access to their personal health information and an opportunity to monitor their own health while in the acute care setting. They have the potential to improve quality of care and empower patients to participate in their treatment. These portals can also help families stay informed about their loved ones especially when they are unable to accompany at bedside due to social distancing restrictions as the COVID-19 pandemic lingers. Despite the potential benefits of inpatient portals, research has shown that patient adoption remains low. There is significant research on factors that influence patients’ use of portals, but less research exists on physicians’ perspectives on the use of these platforms. Outpatient portal studies have shown that provider endorsement drives patients' adoption of these systems.

OBJECTIVE

The objective of this review is to better understand provider attitudes towards this technology, specifically inpatient portals. This insight can help improve patient and physician satisfaction, uptake, and the overall quality of care.

METHODS

A systematic literature review, was conducted using keywords for physicians’ attitudes and perspectives towards patient portals and personal health records (PHRs). Databases included “PubMed/Medline,” “Web of Science,” and “Scopus”.

RESULTS

A total of 4199 articles was collected. Two reviewers performed title/abstract screening and full-text screening independently. A total of 10 articles addressing inpatient portals were included in the review. Common themes identified include communication, concerns with patient access to information on the portal, and impact on workload. Several studies also included physicians’ suggestions on portal functions.

CONCLUSIONS

Physicians perceived inpatient portals to be beneficial to patients and saw improvement in communication as a result. In studies where physicians had no prior experience using patient portals, concerns were expressed about privacy issues, patients’ ability to access lab results and information, and the portal’s potential impact on existing workflow. Physicians suggested that improving training on portal use and including them during the design process would encourage portal use.

CLINICALTRIAL

N/A
Tsunami Early Warning System Based on Maritime Wireless Communication
Authors: Aryanti Karlina Nurendyastuti  , Mochamad Mardi Marta Dinata  , Arumjeni Mitayani  , Muhammad Rizki Purnama  , Mohammad Bagus Adityawan  , Mohammad Farid  , Arno Adi Kuntoro  , Widyaningtias
Published: May 2022

Tsunami buoy, linked to satellite, is commonly used as a tsunami early warning system but has been discovered to have several drawbacks such as the need for approximately 5 minutes to issue an early warning for a tsunami after detecting the initial wave as well as its fragility. It was also reported that the twenty-two buoys placed in the Indonesian seas from 2012 to 2018 were damaged and missing. Therefore, this study proposes a new method for tsunami early warning by integrating ship-to-ship maritime wireless communication. It is important to note that vessels or fishing boats with over 30 GT have the ability to travel more than 100 nmi (approximately 180 km) from the shoreline and can be equipped with point-to-multipoint VHF radio communication. Meanwhile, smaller boats on the fishing ground located approximately 2-5 km from the shore can use a WiFi network to communicate like a wireless mesh while the existing terrestrial network can be used for the ship-to-shore communication between boats and land stations. This system is expected to provide significant benefits for a fishing town such as Pangandaran, West Java, Indonesia which is directly facing Java Megathrust in the Indian Ocean. Therefore, a tsunami numerical simulation was conducted in this study using Shallow Water Equation which involved a hypothetical tsunami simulated from the possible fault source which is approximately 250 km from the source. Moreover, the vessel’s location was assumed to be in line with the fishing ground while the arrival time of the tsunami was estimated from the model to be 22.5 minutes and compared to the relay time of the proposed system which was approximately 5.4 seconds. This is faster in terms of delay than the existing system which relays information through satellite at approximately 5 minutes in an ideal condition and also has the ability to reduce the need for tsunami buoys.
Implementation of Agent Based Modelling to Observe the Evacuating Behavior at Faculty of Engineering Building, University of Bengkulu, Indonesia
Authors: Hardiansyah  , Fitrianip Wida , Edriani Annisa Fitria , Hardiansyah Robi , Lestyanti Rizka , Mase Lindung Zalbuin
Published: May 2022

Evacuation is an important issue during the occurrence of an earthquake, due to the influence of people’s responsive behaviours to the disaster. This indicates the occurrence of overcrowded conditions, which causes the conflict of people’s movement. It is also one of the main reasons the process of evacuation is difficult, leading to the necessity to specifically model the movement within each building. Therefore, this study aims to analyze the earthquake evacuation modelling in Faculty of Engineering building, University of Bengkulu, Indonesia. This used a multi-agent programmable modelling environment known as NetLogo, which adopted an ABM model that is often utilized to observe elemental movement response. The agents occupying the building also moved to the stairs and evacuation doors, for exit towards the assembly point, which was located in front and behind Faculty of Engineering. The agent-based modelling is then conducted by inputting the layout of the building and the number of occupants in each room. Furthermore, the simulations were performed by considering various agents’ capacity in the building, during the evacuation. The results showed the time taken for the agents to exit the building during the disaster. This confirmed that the required exit time generally decreased with the increasing population percentage in the building. During this process, the conflict point also occurred around the corridor of Floors 1 and 2 (T1, T2 and T3), as well as the exits of the building (P1, P2, P3, and P4). This was due to the occurrence of a high density when agents carry out evacuation movements. Based on these results, the placement of signs was recommended, as guidelines during the evacuation process.
Airfield Asphalt Overlay Design for Non-conventional Pavement Structures: A Case Study of Airport in Indonesia
Authors: Rahman Taqia , Suhendro Bambang , Sartono Wardhani , Nawangalam Purbolaras , Hardiyatmo Hary Christady
Published: May 2022

Airfield pavements begin a gradual deterioration from several sources, including traffic load and environmental conditions. To achieve its intended design life, routine maintenance, repair, and rehabilitation should be performed. There are considerable research and studies conducted on the design and practice of pavements rehabilitation/overlay for typical airfield pavements. However, most of the existing guidelines and studies are only suitable for pavements with conventional structures. There has been no detailed investigation into the practice of airfield asphalt overlay for non-conventional pavement structures, such as chicken claw /Cakar Ayam pavement system and nailed-slab system. In the present article, challenges and issues for airfield asphalt overlay design for non-conventional pavement structures were examined based on an actual runway rehabilitation project in one of the major airports in Indonesia in 2015. The overlay design procedure, the evaluation of the existing pavement condition, including visual surveys and deflection tests, and the pre-overlay treatments were also discussed. In addition, a finite element (FE) simulation to model the non-conventional pavement structure was developed to calculate the required overlay thickness. The result showed that, during the overlay design of non-conventional pavement structure, data from falling weight deflectometer (FWD) could not be directly used to estimate the back-calculated layers moduli because of the difference in the geometric features of the pavement structure. Moreover, the FE model can be a robust tool to simulate the complex three-dimensional geometric features of a non-conventional pavement and important loading conditions, such as interface shear bond of overlay, that are usually not available in other tools, such as FAARFIELD. Finally, this study showed that the additional asphalt overlay could reduce the fatigue stress at the bottom of the existing slab and vertical stress at the top of the subgrade, resulting in overall smaller stress levels
Learning Grit and the Intervening Effects of MOOCs in Learning the English Language among College Students
Authors: Dapiton, PhD Ethelbert P. , Sibug, EdD Harvey Ian G.
Published: May 2022

Learning a foreign language such as English usually takes a considerable amount of effort on the part of non-native speakers. The English language as the modern-day lingua franca in almost all aspects of global communications spanning from business to the academe requires that students should be adept of it after they finished their tertiary education. The Southeast Asian Region in which the Philippines belong, is trying to catch-up with the global productivity index that must produce college graduates that are adept in using the English language in order to be competitive. Learning English in college through the use of traditional teaching methods makes students disinterested and disengaged in their course works. The advent of technology specifically the Internet has offered an alternative method to learn English in a more interesting and engaging way through synchronous and asynchronous learning methods such as the massive open online courses (MOOCs). This learning modality has eased the tension of acquiring the necessary English language proficiency among college students. This study is anchored on the structural equation modelling about the effects of MOOCs in learning the English language along with their learning grit from the vantage point of Filipino college students.
The Effect of Opposite-Gender Preference in Teachers’ Grading
Authors: Chen Rain , Hsu Wen-Chun , Huang Chen-I , Hsiao Yu-Chin , Zhang Yun-Zhen
Published: May 2022

Higher education plays an important role in passing on of knowledge, and grading from teachers to students may significantly affect these students’ development in the future. Gender preference has been extensively explored in various domains. A common question is whether gender preference exists in teachers’ grading. If so, would teachers give students of the opposite gender a higher grade without noticing this opposite-gender preference? A survey was conducted between 2020 and 2021, and a total of 1,604 student scores were collected. The independent samples t-test and ANOVA were performed to test the collected data. This study found that first, female teachers, compared to male teachers, gave significantly higher scores (p < 0.000). Second, male teachers’ grading was not affected by the gender of their students (p = 0.067). Third, female teachers gave male students, compared to female students, significantly higher scores (p = 0.003). These preliminary findings suggest that opposite-gender preference may exist. However, this study only collected simples from teachers and students from the department of design, and therefore, it is not clear yet whether the above preference can be observed in all education settings.