bluuebunny/crossref_metadata_2025 huggingface dataset:
Adaptation of the Russian version of the Aging Perceptions Questionnaire (APQ)
Authors:   St. Petersburg State University, Petrash Marina , Strizhitskaya Olga ,   St. Petersburg State University, Krupina Kristina ,   St. Petersburg State University
Published: August 2024

The work is devoted to the adaptation of the “Perception of Aging” questionnaire based on the English-language Aging Perceptions Questionnaire (APQ). Modern scientific knowledge has a significant amount of data in the field of psychology of aging, interest in which does not fade, and the aging process is studied from various angles. Researchers more often turn to the problem of constructing a productive old age, the planning of which is recommended to begin at earlier stages of life. The results of modern research indicate that a positive perception of aging is a predictor of quality of life in old age and contributes to various aspects of health in old age. In this regard, the question arises about psychodiagnostic tools that allow us to identify the specifics of the perception of aging. Even though that there are currently studies on this problem, there is no version of the questionnaire that will allow assessing the perception of aging in a Russian sample. This study examined the reliability and construct validity of the English version of the APQ Perceptions of Aging Questionnaire. The study involved 229 people aged 29 to 68 years. Reliability was assessed by calculating Cronbach’s α and showed internal consistency both for the entire questionnaire and across gender groups. To test the convergent validity, the Health-Promoting Lifestyle Profile questionnaire, the K. Riff Psychological Well- Being Scale, the Australian Healthy Aging Questionnaire, and the Positive Affect and Negative Affect Scales were used. As a result of exploratory factor analysis, six scales were identified: “Consequences negative”, “Control positive”, “Emotional representation” and “Unstable image of old age” (Timeline (cyclical)), “Consequences positive”, “Control negative”. Analysis of convergent validity showed the connection of the selected scales with indicators of psychological and physical health. The Perceptions of Aging Questionnaire is a simple and flexible method for assessing the image of aging.
The life situation of post-guardianship in the representations of members of kinship guardian families
Authors:   Herzen State Pedagogical University of Russia, Korjova Elena , Tuzova Olga ,   Herzen State Pedagogical University of Russia, Karasaeva Aliya ,   Herzen State Pedagogical University of Russia, Povkhova Anastasia ,   Herzen State Pedagogical University of Russia
Published: August 2024

The completion of guardianship is an important period for all family members and can be considered as a special life situation. The study of the post-care period allows us to assess the quality of the passage of the previous stages and to see the prospects for further development of both the foster children (post-foster children) and the guardians (post-guardians). Currently, this stage of the life of foster families is not sufficiently reflected in scientific research. There is a need to supplement empirical data on the problems of foster families after the end of guardianship. The purpose of the study is to study the features of the life situation of postguardianship in the representations of post-guardians and post-foster children. To achieve this goal, a questionnaire has been developed that contains questions aimed at identifying the structure of the post-guardian family, studying subjective assessments of changes in the life situation, analyzing the level of maintaining relationships in the “post-guardian — post-foster children” system, subjective assessment of the level of maintaining social contacts, identifying the ability and willingness of the former guardian to transfer responsibility, subjective assessment of the post-foster children readiness for independent identification of the level of satisfaction with the result of interaction in the family. The study involved 214 members of kinship guardian families. Of these, 112 orphaned children aged 18–25 years and 102 post-guardians aged 45–75 years. The analysis of the responses showed differences in the ideas about the life situation of post-guardianship members of kinship guardian families. Positive ideas about the life situation were revealed in the post-foster children, who at the time of the study had already created their own families and those who live independently. Post-foster children and postguardians, living together, gave lower ratings for the categories of the situation under consideration. Lower ratings were revealed in the representations of post-guardian grandmothers than in the representations of post-guardian aunts. Post-guardian grandmothers living alone, in all the categories under consideration, have negative ideas about the post-guardianship situation, which indicates the need to develop and organize psychological support.
The factor of emotional non-acceptance of the disease in patients addicted to synthetic cathinones
Authors:   St. Petersburg State Pediatric Medical University, Granovskaya Elizaveta ,   Bekhterev National Medical Research Center of Psychiatry and Neurology
Published: August 2024

Recently, synthetic cathinone addiction has spread globally, particularly among youth, due to the popularity of “club” drugs and stimulants. The patient’s motivation to quit psychoactive substances is crucial for effective treatment and rehabilitation. However, motivation for treatment is hindered by anosognosia, the inability of addicts to recognize their condition. Among the aspects of anosognosia, emotional non-acceptance of the disease is significant. The aim of the study is to identify socio-demographic and clinical parameters that are associated with emotional nonacceptance of the disease in patients with addiction to synthetic cathinones to determine psychotherapeutic targets of significance in the construction of rehabilitation programs. Based on the “Emotional non-acceptance of the disease” scale from the drug anosognosia questionnaire developed in 2020, groups of individuals with high and low scores were formed. These groups of patients were compared according to several clinical and socio-demographic parameters. Based on the conducted study, the significance of such factors as: presence of children, service in the army, craniocerebral trauma in the anamnesis and others. Thus, a high level of family support, sufficient material condition of the family and positive attitude of parents to the patient, as well as consistency between the roles of “parent” and “drug addict” are factors that contribute to the emotional acceptance of the disease (drug addiction). At the same time, the influence of clinical characteristics, such as the severity of residual-organic mental changes, personality transformation due to addictive behavior, can hinder emotional acceptance of the disease.
Semantics of Predicative PrepositionalCase Forms of Noun: State and Evaluation
Authors:   The Pushkin State Russian Language Institute, Huang Yangyu
Published: August 2024

The article is devoted to the study of predicative prepositional-case forms of the noun, capable of expressing thoughts about the state, in varying degrees approaching the category of the state. The relevance of the research topic is due to the development of personal bisubstantial construction in modern Russian, in the syntactic conditions of which the idea of the state and/or evaluation is further developed. Prepositional-case forms like v forme, v trende, v zamote (in form, in trend, in fact) occupy an intermediate position between the noun and the category of state, and therefore the purpose of the study is to specify their status depending on the ratio of this state and evaluation in their semantic structure. The methodological basis of the research is the theory of transitivity developed by V. V. Babaytseva, as well as the transitivity scale as the main methodological tool, the hypothesis of syntactic constructions of bisubstantial sentences put forward by N. A. Gerasimenko, as well as the theses of K. Ya. Segal and M. S. Milovanova on the axiological semantics of forms the value-evaluative potential of which is realized in certain syntactic constructions. The research material is the prepositional case forms of the noun extracted from the National Corpus of the Russian language and social networks, functioning in a predicative position and denoting the state and/or assessment. The article proposes a variant of the analysis of specific word forms from the point of view of the degree of their distance from the class of nouns and their convergence with the category of state (degree of predication), which is the reason for the novelty of this work. The article concludes that the increase in the number of such lexemes is associated with the actualization of bisubstantial sentences, provoked by the tendency to emancipation of prepositional-case forms of the noun, on the one hand, and the course outlined in the consciousness of modern man on his personality, on himself as an object of cognition, on the other.
Language Reflection: Digital Etiquette
Authors:   Moscow School of Social and Economic Sciences, Lukinova Olga V.
Published: August 2024

The author argues that modern digital etiquette is in the process of formation and constantly evolving. Old norms of business correspondence do not always align with the current conditions and users’ views on effective and ethical communication. Researchers are faced with the question of what can serve as a source of information on emerging ethical and linguistic norms. The purpose of the article is to prove that the analysis of language reflection can be an effective way to study the norms of modern digital etiquette. The study conducted in the fall of 2022 used the method of analyzing the corpus of language reflection. The dataset obtained through a two-stage survey includes an assessment by 3464 Internet users of 92 formulas and expressions used in digital correspondence. The article analyzes the state of modern digital etiquette, substantiates the need for the analysis of language reflection to study ethical and speech norms, describes the methodology of studying language reflection through surveys, and con cludes on the necessity of analyzing language reflection to capture trends in digital etiquette. The novelty of the article is determined by at least two factors. Firstly, it addresses the topic of unexplored and unstable norms of digital etiquette. Secondly, it highlights the need to analyze language reflection on the rules of speech behavior on the web. The significance of the study is related to the fact that digital etiquette norms are constantly changing, and researchers need a tool to capture such changes. The practical value of the study is that it enables certain recommendations on email etiquette and warns against potential communicative failures in internet communication.
Anti-Fairy Tales in the Works by Vladimir Vysotsky and Robert Rozhdestvensky: Genesis and Artistic Findings
Authors:   LLC “Event”, Sipkina Nina Ya.
Published: August 2024

The author explores, for the first time, Vladimir Vysotsky’s anti-fairy tales (“The Fairy Tale Song about Evil Spirits”, “There is no more Lukomorye”, “Verses of Evil Spirits”) and Robert Rozhdestvensky (“The Tale of the Blacksmith who Stole a Horse”, “The Monologue of the King of Animals”) in a comparative aspect. These texts have common foundations with folklore genres (myth, bylichka (folkloric account), byvalschina (true story), fairy tale) and literary fairy tale. The purpose of the article is to disclose the artistic features and the genesis of the anti- fairy talesby Vysotsky and Rozhdestvensky. It is revealed that the roots of folklore works go back into the mythological layers of Russian national culture associated with the development of artistic consciousness of people of prehistoric times. The myths that reflected a person’s idea of the world were of a religious nature and did not cause doubt as long as they were believed in. After the belief in animate gods disappeared, myths began to be perceived as fiction and become a bylichka (folkloric account), byvalschina (true story), fairy tale, etc. It is concluded that the anti-fairy tale is based on the attributes of a fairy-tale model, which are used by the authors of works to identify the imperfections of the real world, to ridicule it. One of the means of creating comic effects in the studied anti- fairy tales is hyperbole. In turn, hyperbolization reveals the ideological intent of the works, enhancing their aesthetic and authorial sound. Bearing the traditions of folklore genres (myth, bylichka (folkloric account), byvalschina (true story), fairy tales, etc.) and literary fairy tales, the anti-fairy tales by Vysotsky and Rozhdestvensky help the reader to create a contrast between the fabulous idea of the world and the imperfect world of reality.
Estate Topos in Ivan Bunin’s Prose
Authors:   Ural Federal University named after the First President of Russia B. N. Yeltsin, Gong Zehui
Published: August 2024

The article is devoted to the analysis of the manor topos and the image of the estate in the prose by Ivan A. Bunin. The relevance of the study lies in the fact that the concept of “estate topos” is not sufficiently developed in the Chinese humanities. The article considers only a few works by Chinese researchers. The works of Russian scholars are more focused on Bunin’s poetry. Based on the theory of the estate topos, the article shows that еhe image of the estate in the writer’s prose becomes the most important. In the study of the dynamics of this image, three stages of its formation and functioning are distinguished. Between 1890 and 1900 the image develops, the locus of the garden is clearly indicated (the story “Tan’ka”). The period of 1900–1919 is characterized by deepening of interpretation. From the poeticization of estate life in “Antonovka Apples” the author proceeds to deep reflections on the reasons for the extinction of noble nests in “Sukhodol”. In the period of 1920–1940 the image of the estate is built in organic correlation with the theme of the house, the lost home, the lost native nest. This period is represented by the story “Mitya’s Love”, the novel “The Life of Arseniev”, the collection of stories “Dark Alleys’. The novel “The Life of Arseniev” is a kind of culmination in the disclosure of the estate theme in Bunin’s prose. The image of the estate in the novel is associated with the nature of the hero’s memories, it changes along with the change of his emotional experiences in different periods of life from childhood to adolescence, and then to youth. In the 1920s and 1940s, the content and tonality of the estate topos were significantly corrected. The estate is interpreted as an absolute value, imprinted by memory and preserved thanks to memory in the space of culture. The image of the estate in Bunin’s work acquires semantic volume and bright originality, associated, among other things, with the historiosophical and spiritual understanding of this phenomenon in Russian culture.
Features of Teaching Russian Literature in a Technical University in China: Ways of Increasing Motivation to Study It
Authors:   Harbin Institute of Technology, Xie Chunyan , Erofeeva Inna N. ,   St. Petersburg State University
Published: August 2024

The article is devoted to the teaching of Russian literature in a Chinese technical university. The purpose of the article is to present ways of increasing motivation to study Russian literature. The author offers various ways of working with works of literature, including a comparison of works with similar plots and ideological basis, written by authors from different countries. One of the reasons for the need to address this problem is the peculiarities of psychology and atti tudes towards reading among modern young people. The results of the analysis of the knowledge of Chinese students in the field of Russian literature, conducted by the author, show that students do not know it well, however, thanks to the influence of their parents, they respect and would like to know more. Reforms in the field of education in China make it possible to organize various types of work on the study of literature and culture with students: new courses of lectures, seminars, discussions. The article describes the elective creative courses organized at Harbin Polytechnic University for students of various specialties, the purpose of which is to form knowledge in the field of Russian literature and culture, teach the analysis of Russian literature, increase interest in studying the history of Russia, and the peculiarities of the Russian mentality. When developing course materials, the author proposes to rely on theoretical research in the field of basic concepts and keywords of Russian culture. The result of this work is the thematic structuring of the lessons of the course, the identification of the most significant topics and works for young people and for understanding Russian culture. The author comes to the conclusion that properly organized in accordance with the recommendations of researchers in the field of educational reforms, linguoculturology, sociology classes can greatly increase interest in Russian culture, literature and reading in general.
Scientific Discourse with the Key Term Artificial Intelligence
Authors:   Moscow University for Industry and Finance “Synergy”, Slozhenikina Yulia V. , Kozlovskaya Natalia V. ,   Institute for Linguistic Studies of the Russian Academy of Sciences, Musaeva Anastasia S. ,   Moscow City University, Samara Branch
Published: August 2024

The authors argue that at present, a new scientific object, a discourse with the key term artificial intelligence (AI), has formed in the language of science. The state of the discourse is characterized as extremely debatable. From a substantive point of view, the articles have the object of AI technology, and the subject is the problems of the emergence of AI systems in various branches of human activity. The formation of AI discourse is at the initial stage, as evidenced by the elements of linguocreativity in the texts of institutional discourse, characterized by the lack of imagery, personalities and terminology. The authors emphasize the novelty of this phenomenon and the comprehensiveness of AI technologies with different words and word combinations with temporal and spatial semantics. In the discourse lexical means create the effect of speed, pressure, quantitative and qualitative growth of new AI systems. The key words of the new discourse are advantage, benefit, trust, challenges. The discourse is characterized by metaphorical language and a large number of personifications. From axiological positions the value of AI is not questioned. From the point of view of determining the author’s goal-setting, the purpose of the text in the discourse, new goals are affirmed, namely the justification of the opportunities and limits of the application of AI. The communicative strategy of the authors of the articles is aimed at creating the effect of readers’ involvement, synergy in achieving the goals. For this purpose, a variety of rhetorical means and techniques are used (personal pronouns, personal forms of verbs, rhetorical questions, oxymoron, phraseological expressions, winged words, epithets, etc.). At this stage of the existence of scientific discourse with the key word artificial intelligence is found similar to the artistic discourse, as there is the creation of a new scientific object, looking for approaches to its linguistic positioning, forms of putting forward the scientific result.
The Landscape Code of Russian Culture in Educational Dictionary Created for Foreign Philology Students
Authors:   Herzen State Pedagogical University of Russia, Koyupchenko Polina N.
Published: August 2024

The article is devoted to the problem of landscape code of Russian culture lexicographic description in teaching advanced Chinese philology students Russian as a foreign language. At present, the culture codes linguistic description contributes to the explication of hidden cultural meanings, coded for foreigners studying the Russian language even at the high level. The “decoding” of hidden meanings requires purposeful work, without this work complete cultural information comprehension is impossible. The appeal to the culture code as a study subject is especially relevant for teaching philology students, since it is assumed that philologists should have the ability not only to perceive the different texts content, but also to penetrate into the Russian word imagery, into its value potential and understand the estimation justification. After analyzing the existing studies, one can conclude that the landscape culture code is one of the main codes, it has a significant impact on the national character, mentality, picture of the world and the linguistic picture of the world of the Russian linguocultural community. The landscape kinds names have not yet become the subject of a purposeful methodological description, and the corresponding lexical-semantic group has not been identified in ideological dictionaries. In this regard, applying the component analysis method we determined the lexical-semantic group “Names of landscape kinds” volume and structure and the educational group of the same names, including 8 subgroups. The article proposes an educational lexicographic description of the verbal landscape culture code represented by the lexical-semantic group. The dictionary entry of the educational dictionary “Verbal culture codes in the language vocabulary” has a multicomponent structure. The selected zones of the dictionary entry (interpretation, synonyms, associations, epithets, etc.) contribute to the Russian culture code “decoding”, which is especially relevant in methodology of teaching Russian as a foreign language to Chinese philology students.
Russian Studies at Volgograd State Socio-Pedagogical University: History and Modernity Congratulations with Russian Language Day
Authors:   Volgograd State Social and Pedagogical University, Suprun Vasilii I. , Dekatova Kristina I. ,   Volgograd State Social and Pedagogical University
Published: August 2024

The authors argue that throughout the existence of the Volgograd State Socio-Pedagogical University, the Russian language has always been among the main subjects of training the students, future teachers, since it is impossible to provide the necessary level of the educational process at school without it. The Department of the Russian Language at the Volgograd Pedagogical Institute was established in 1932. Prominent Soviet linguists V. A. Brim, M. F. Belyaev and others worked in it. During the Great Patriotic War, many students and teachers of the Department defended the country at the fronts, worked in the rear, contributing to the victory over the enemy, and the institute temporarily suspended work. In the post-war period, scholarly traditions were laid at the Department, which were continued in its subsequent history. The founder of the Volgograd Ethnolinguistic school is L. M. Orlov, the research in Russian dialectology was continued by R. I. Kudryashova, E. V. Brysina and others. The traditions of onomastic research were laid down by I. G. Dolgachev. The famous Russian onomatologist V. A. Nikonov in 1988 invited Volgograd researchers to organize a conference “Onomastics of the Volga region”, and since then the permanent organizing committee has been in Volgograd, and the conferences have become important events in the scholarly life of Russia. The foundations of linguodidactics and methods of teaching the Russian language, as well as derivatology were laid by the works of Z. A. Potikha. The phraseology of the Russian language was studied by N. F. Alefirenko, under whose leadership a school of phraseologists was created, which is now headed by K. I. Dekatova. A significant contribution to modern Russian studies is made by the works of V. P. Moskvin, T. N. Kolokoltseva, L. A. Shestak, M. F. Shatskaya, E. I. Aleshchenko, etc. The Department of the Russian Language has a successful combination of experienced and young scholars, there is a successfully operating postgraduate school, dissertations on Russian studies are regularly defended in the Dissertation Council. This serves as a guarantee for the further successful development of Russian studies at the Volgograd State Socio-Pedagogical University.
Estagiários da vida
Authors: Da Silva Menezes Amanda
Published: August 2024

Um pequeno poema sobre a vivência do estágio, que faz relação com a vivência cotidiana e com as etapas da vida. Essa analogia pretende nos colocar diante do caráter de eternos aprendizes, independentemente do momento e do local em que nos encontramos.
Simulação numérica de fluxo e transporte de cromo na Floresta Estadual Edmundo Navarro de Andrade, município de Rio Claro – SP
Authors: Cunha Caroline Favoreto , Teramoto Elias Hideo , Kiang Chang Hung
Published: August 2024

A área de estudo, localiza-se sobre terrenos da Floresta Estadual Dr. Edmundo Navarro de Andrade, uma importante reserva ecológica para o município de Rio Claro/SP, e encontra-se sobre sedimentos das formações Corumbataí, Serra Geral, Rio Claro e Depósitos Cenozoicos. Foram constatadas concentrações anômalas de cromo, que excedem o limite de potabilidade definido pelo CONAMA n°396 (0,01 mg/L) na área de estudo. Para o entendimento do fluxo, bem como o entendimento do comportamento geoquímicos deste metal, e os fatores que controlam o desenvolvimento desta pluma, realizou-se o modelo de fluxo e a simulação de transporte do cromo. As simulações foram feitas a partir do método dos elementos finitos, utilizando-se do software FEFLOW. A pluma resultante da simulação demonstrou forte controle da sorção e da dispersividade transversal em seu comportamento.
Trends and Implications of Ribosome-associated Protein Quality Control in Diseases: A Bibliographic Analysis
Authors: Chen Leijie , Song Wanjuan , Qing Yumin , Tan Yuyong , Liu Jia , Lv Liang
Published: August 2024

Objective:

Ribosome-associated protein Quality Control (RQC), comprising
several well-organized processes and crucial factors, provides translational surveillance
in cells by recognizing and degrading aberrant nascent proteins arising from ribosome
stalling. Although rapid progress has been made in RQC, a bibliographic analysis of
RQC-related literature studies for the overall trends and research progress, particularly
the correlation of RQC with diseases, is absent.

Methods:

We obtained scientific outputs of global RQC between 1999 and 2022 by
Web of Science Core Collection (WoSCC). CiteSpace, VOSviewer, and a package of R
called bibliometrix were applied to explore the current research status, hotspots, and the
relationship between RQC and diseases.

Results:

A total of 429 articles have been included in this study, and the number of published
studies increases annually. The United States and Germany have been found to
lead in this field. An analysis of the keywords has shown “initiation”, “aggregation”,
“structure basis”, “elongation”, and “degradation” to be the emerging themes of RQC.
Keywords co-occurrence has shown E3 ubiquitin ligase to bridge RQC and neurodegeneration.

Conclusion:

Through a summary of the current studies on RQC, our study has provided
evolutionary trends and frontiers in this field by mathematical analysis and visualization,
implying the potential of RQC in neurodegeneration and other diseases.

result:

A total of 429 articles were included, and the number published increases annually. The United States and Germany lead in this field. Analyzing the keywords showed that “initiation,” “aggregation,” “structure basis,” “elongation,” and “degradation” were the emerging themes of RQC. Keywords co-occurrence showed that “E3 ubiquitin ligase” bridges RQC and neurodegeneration.
Immunoglobulins: Mechanistic Approaches in Moderation of Various Inflammatory and Anti-Inflammatory Pathways
Authors: Pasricha Chirag , Bansal Nancy , Kaur Rupinder , Kumari Pratima , Jangra Sarita , Singh Ravinder
Published: August 2024

Immunoglobulins (Ig) are proteins that help fight infections. IgG (IgG1, IgG2, IgG3,
IgG4), IgM, IgA, IgD, and IgE are the five immunoglobulin subtypes that make up the majority
of our immune system. Beneficial effects have been observed on the administration of Ig in diseases
like Kawasaki, multiple myositis, chronic inflammatory demyelinating polyneuropathy
(CIDP), and immune thrombocytopenia purpura (ITP). The Fc region, FcγRs, and FcRn of the
IgG interact to provide both pro- and anti-inflammatory effects. IgM blocks immune-mediated
inflammation using N-like glycans. It has been demonstrated that IgM demonstrates its antiinflammatory
activity through IgM anti-leukocyte auto-antibodies (IgM-ALA). Since IgA is the
second most prevalent and important Ig that operates on the primary objective in the immune
system, which exhibits inhibitory signals in the body and generates inflammation in host cells, it
plays a critical role in controlling mucosal homeostasis in the gastrointestinal (GI) tract. Additionally,
it has been discovered that activating FcαRI boosts cytokine responses at different levels.
IgD, a mysterious class of Ig once discovered, has a role in many disorders, including myeloma
and Hodgkin’s disease. The stability of IgD with development shows a different role,
which has an advantage for the host's survival. IgE is mainly associated with many allergic diseases
(food allergies), mediates type 1 responses, and has defenses against parasitic infections,
which makes it an important parameter for monoclonal antibodies. Studies showed the possible
roles of immunoglobulins, from which it came to light that immunoglobulins have their functions
as agonists and antagonists in inflammation.
Novel Approaches for the Enhancement of Bioavailability of Drugs: An Updated Review
Authors: Dash Jyoshna Rani , Pattnaik Gurudutta , Samal Himansu Bhusan , Pradhan Gangadhar , Baral Choudhury Pratyush Kumar , Behera Biswajit , Kar Biswakanth
Published: August 2024

In medicine, bioavailability is the percentage of a drug that enters the bloodstream and
can be used to treat a patient. It has proven challenging throughout time to develop techniques that
allow oral administration of most drugs, regardless of their properties, to achieve therapeutic systemic
availability. This will be an impressive feat, considering that over 90% of pharmaceuticals
are known to have limitations on their oral bioavailability. Improving bioavailability is crucial for
optimizing the efficacy and safety of drugs. This review covers a wide range of techniques, including
physical, chemical, and formulation approaches, highlighting their mechanisms, advantages,
and limitations. Inhibitions of efflux pumps, inhibition of presystemic metabolism, and innovative
drug delivery systems that capitalize on the gastrointestinal regionality of medicines are some of
the new techniques that have drawn increased interest. Nanotechnology in pharmaceuticals is also
being used in this field. We have collected the literature data from 2009 to 2024 using Science Direct,
PubMed/Medline, Scopus, and Google Scholar.
Re-evaluating the Relationship between Cosmetic Products and Cancer: An Investigative Review of Paradigms
Authors: Kumar Philips , Chakroborty Prantik Kishor , Wilson Kashish , Goyal Rajat , Gupta Sumeet , Saharan Anjali , Rani Nidhi , Sharma Prerna
Published: August 2024

Cosmetics are items that are used to glorify or change facial looks and appearance as
well as provide fragrance to the body. Their main aim is to cleanse, beautify, facilitate attractiveness,
and change physical looks. Women use many different beauty products, such as skin care,
hair, perfume, oral hygiene, and nail care items, which may include harmful substances that are
threatening to their health. The controversy around cosmetics and beauty products promoting cancer
threat has grown over the previous few years. According to data from the European Cancer
Registries, postmenopausal and very young women are now seeing an increase in the occurrence
of breast cancer, which is the more frequent form of cancer in women. Genetic predisposition,
long-term hormone replacement treatment, and various environmental variables, including air pollution,
agrochemicals, alcohol, and specific consumer goods like cosmetic additives, are some of
the causes of breast cancer. Additionally, the USFDA made all adverse event reports, including
those involving concerns about cosmetics, publicly accessible via the Adverse Event Reporting
System (CAERS) of the Centre for Food Safety and Applied Nutrition in 2016. In this period of
modernization, CAERS is of limited use since there is a lack of different supporting data, such as
demographic information, medical history, or linked product usage, and because the existing data
is vulnerable to severe reporting bias. Despite the system's potential to protect the public's health,
the database's future usefulness will depend on a wide range of reporting participants, more thorough
reporting, and concurrent investments in regulatory science and enhanced molecular techniques.
Oxidized Ethylene Glycol/ZrO2-coated NiTi Orthodontic Arch Wires: Surface Characterization and Electrochemical and Corrosion Studies
Authors: Perumal Abisha , Sridharan Gokul , Ganapathy Dhanraj , Madhivanan Keerthana , Sundramoorthy Ashok K.
Published: August 2024

Background:

Orthodontic arch wires, typically made of Nickel Titanium (NiTi), are
widely utilized in dental procedures for correcting teeth misalignment and jaw issues due to
their favorable mechanical attributes and cost-effectiveness. However, these NiTi wires are
prone to corrosion in the oral environment, leading to diminished mechanical stability, compromised
aesthetics, and potential health concerns for patients.

Objective:

There is a growing demand to augment the corrosion resistance and stability of orthodontic
wires. Hence, this study aimed to address these issues. Herein, zirconium dioxide
(ZrO2) and oxidized ethylene glycol (OEG) films were deposited onto NiTi wires to improve the
corrosion resistance and stability.

Methods:

NiTi wires were modified by a two-step process involving electrodeposition of ZrO2
and oxidized ethylene glycol (OEG) film. The surface characterizations of coated material
(OEG/ZrO2/NiTi) were carried out by using Field Emission Scanning Electron Microscopy (FESEM),
Energy Dispersive X-ray Spectroscopy (EDS), and Electron Microprobe Analysis (EMap)
to confirm the elemental composition of the coated NiTi wire.

Results:

The OEG/ZrO2/NiTi wire exhibited a potentiodynamic polarization resistance of
547037 Ω and higher stability than the bare NiTi wire (396421 Ω). The corrosion rate for
OEG/ZrO2/NiTi wire was found to be 0.040 mm/year, which was comparatively lower than a
bare NiTi wire (0.069 mm/year). Due to the formation of OEG/ZrO2 film, NiTi wire became
electrically insulative and showed a higher impedance than bare NiTi wire.

Conclusion:

The bilayer coating of ZrO2 and OEG has proven to significantly improve the corrosion
resistance and stability of the wires. Thus, these materials can be considered for coating
orthodontic arch wires with improved corrosion stability.
Agrimonolide Inhibits the Malignant Progression of Non-small Cell Lung Cancer and Induces Ferroptosis through the mTOR Signaling Pathway
Authors: Zhang Xiaoling , Cai Wei , Yan Yiguang
Published: August 2024

Background:

Non-Small Cell Lung Cancer (NSCLC), a prevalent type of lung cancer, has a poor
prognosis and contributes to a high mortality rate. Agrimonolide, which belongs to the Rosaceae family, possesses
various biomedical activities. This study aimed to explore the efficacy and mechanism of agrimonolide in
NSCLC.

Methods:

The viability, proliferation, and tumor-forming ability of A549 cells were detected using the Cell
Counting Kit-8 assay (CCK-8) assay, EdU staining, and colony formation assay. The cell cycle was detected
using flow cytometry. Cell migration and invasion were detected using wound healing and transwell assays.
Western blot was used to detect Epithelial-Mesenchymal Transition (EMT)-, ferroptosis-, and mechanistic targets
of rapamycin (mTOR) signaling pathway-related proteins. Lipid peroxidation was detected using the thiobarbituric
acid reactive substances (TBARS) assay kit, while lipid Reactive Oxygen Species (ROS) was detected using a
BODIPY 581/591 C11 kit. The level of Fe2+ was detected using corresponding assay kits.

Results:

In this study, agrimonolide with varying concentrations (10, 20, and 40 μM) could inhibit the proliferation,
induce cycle arrest, suppress metastasis, induce ferroptosis, and block the mTOR signaling pathway in
NSCLC cells. To further reveal the mechanism of agrimonolide associated with the mTOR signaling pathway in
NSCLC, mTOR agonist MHY1485 (10 μM) was used to pre-treat A549 cells, and functional experiments were
conducted again. It was found that the protective effects of AM on NSCLC cells were all partially abolished by
MHY1485 pre-treatment.

Conclusion:

Agrimonolide inhibited the malignant progression of NSCLC and induced ferroptosis by blocking
the mTOR signaling pathway, thus indicating the potential of agrimonolide as a prospective candidate for treating
NSCLC.
ANALISIS KINERJA OPERASI PADA TERMINAL CURUG AGUNG KABUPATEN BANDUNG BARAT
Authors: Dien Azzizah Azzahra Farhani
Published: August 2024

Unit analisis yang diteliti yakni Terminal Curug Agung yang bertujuan untuk mengukur kinerja operasi. Lokasi penelitian ini dipilih karena ketersediaan fasilitas pada terminal tersebut masih banyak yang belum ditemukan sehingga muncul terminal bayangan pada Jalan Raya Padalarang yang menyebabkan terhambatnya arus lalu lintas. Berdasarkan observasi pendahuluan, terdapat fenomena permasalahan yang terjadi berupa banyaknya angkutan umum yang melakukan pencarian penumpang di badan jalan sehingga menyebabkan arus jalan di sekitar Terminal Curug Agung menjadi terhambat. Selain itu, pengguna sulit menemukan pos kesehatan, rambu keselamatan jalan, pos dan petugas pemeriksa kelaikan kendaraan umum, jalur evakuasi, perlengkapan darurat, tempat sampah, koridor, taman, informasi terminal, tempat perbelanjaan, ruang istirahat petugas, pusat informasi dan pengaduan, rambu jalur transportasi, sarana ibadah, dan bank. Dengan demikian, tujuan penelitian ini yakni mengetahui kinerja operasi pada Terminal Curug Agung. Metode penelitian berupa metode penelitian deskriptif dengan pendekatan kuantitatif dan kualitatif. Adapun teknik pengumpulan data yakni observasi untuk mengetahui kinerja operasi terminal, kuesioner untuk mengetahui pendapat responden terkait kinerja operasi terminal, dan wawancara untuk mengetahui informasi yang tepat terkait terminal. Hasil dari penelitian ini yakni dimensi emergency situations memiliki interpretasi yang buruk. Sedangkan enam dimensi lainnya yakni dimensi assurance, performance, aesthetics, amenity and easy, convenience, dan availability memiliki interpretasi yang cukup.
ANALISIS DISPARITAS PENDAPATAN KABUPATEN DAN KOTA DALAM SURABAYA METROPOLITAN AREA
Authors: Larasati Aida Fitri , Irsyad Fatimah Ratna Nur , Santoso Eko Budi
Published: August 2024

Kegiatan perkembangan ekonomi perkotaan yang semakin tinggi menyebabkan terbentuknya suatu aglomerasi daerah Metropolitan. Gerbangkertosusila atau Surabaya Metropolitan Area (SMA) merupakan salah satu Satuan Pengenmbangan Wilayah (SPA) yang juga salah satu Kawasan Strategis Nasional. Tingginya laju pertumbuhan ekonomi di SMA tidak selalu serta merta diimbangi dengan kemerataan pendapat di masing-masing kabupaten dan kota di wilayah Surabaya Metropolitan Area. Penelitian ini bertujuan untuk mengetahui disparitas pendapatan yang terjadi diantara kabupaten dan kota di wilayah Surabaya Metropolitan Area dengan menggunakan tiga alat analisis, yaitu Tipologi Klassen, Indeks Williamson dan Indeks Theil . Hasil dari penelitian ini mengindikasikan bahwa kondisi ketimpangan di Surabaya Metropolitan Area dalam kurun waktu 2016-2020 menunjukkan kestabilan dalam tingkat ketimpangan sedang, meskipun laju pertumbuhan cenderung menurun pada tahun 2019-2020. Selain itu, dalam indeks entropi theil dapat disimpulkan bahwa nilai rata-rata ketimpangan pada wilayah SMA (Surabaya Metropolitan Area) tidak melebihi nilai ketimpangan di Jawa Timur.
Evaluación auténtica en contexto universitario a través de portafolios electrónicos de aprendizaje
Authors: Trejo González Hugo
Published: August 2024

El objetivo de este trabajo consiste en presentar los resultados de una intervención educativa a través del portafolio electrónico de aprendizaje como estrategia de evaluación auténtica. Dicho estudio tuvo lugar en una institución de educación superior en México, en el marco de una clase para futuros profesores que cursan una licenciatura en didáctica del francés como lengua extranjera en su noveno semestre. Los estudiantes aprendieron y utilizaron la estrategia de evaluación con base en las necesidades de la materia. En cuanto al trabajo metodológico, se aplicaron cuestionarios para dar cuenta de la perspectiva de los futuros profesores sobre el portafolio de aprendizaje, pero también verificar la apropiación del concepto. Además, este manuscrito presenta la perspectiva del profesor que dirige la intervención en función de lo sucedido en momentos iniciales, intermedios y finales a través de la observación participante. Los resultados muestran un interés elevado por parte de los estudiantes, aprendizaje importante sobre la estrategia y el desarrollo de procesos de metacognición y autoevaluación. Sin embargo, se detectan necesidades significativas de tiempo y recursos para la integración del portafolio electrónico en clase que conllevan un incremento de la carga de trabajo.
Exploring the Impact of Genuineness in Psychotherapy: A Self-Practice/Self-Reflection (SP/SR) Report
Authors: Perlman Candice Fischer , Cáceres-Videla Carolina Eugenia
Published: August 2024

A growing body of evidence has highlighted the limitations of relying solely on positivist research when summarizing SP/SR results since it might hinder pluralistic perspectives from unique backgrounds and life experiences. In the present reflective report, I aim to conduct quantitative and qualitative research on myself to explore the impact of concentrating on genuineness when delivering psychotherapy as a trainee. This article provides concrete examples of how therapists’ authenticity could benefit the therapeutic alliance. The therapist completed the 15-item five-facet mindfulness questionnaire, the Center for Clinical Interventions’ assertiveness questionnaire, the authenticity scale, and the values in action inventory. Clients filled out the working alliance inventory-short, revised version during mid-treatment reviews. Thematic content analysis was applied to the 3000-word written reflective report submitted for assessment as part of the training. The management of difficult emotions coupled with the development of compassion, a practice that promotes EDI, and a cohesive sense of self were some of the benefits I experienced. Emotional awareness is emphasized as the first step towards authenticity, which I facilitated through regular mindfulness practice. Regarding compassion and a paced approach, issues might arise in services requiring outcome measurements to be reduced to the point of recovery by the end of the treatment. The study approaches authenticity as a value constantly pursued in a continuously evolving ideal self. A life of committed professional improvement and practice is warranted, where maintaining authenticity requires ongoing therapist reflection.
Resilience Informatics: Role of Informatics in Enabling and Promoting Public Health Resilience to Pandemics, Climate Change, and Other Stressors
Authors: Iyengar M Sriram , Block Ngaybe Maiya G , Gonzalez Myla , Arora Mona
Published: August 2024

Climate change, local epidemics, future pandemics, and forced displacements pose significant public health threats worldwide. To cope successfully, people and communities are faced with the challenging task of developing resilience to these stressors. Our viewpoint is that the powerful capabilities of modern informatics technologies including artificial intelligence, biomedical and environmental sensors, augmented or virtual reality, data science, and other digital hardware or software, have great potential to promote, sustain, and support resilience in people and communities. However, there is no “one size fits all” solution for resilience. Solutions must match the specific effects of the stressor, cultural dimensions, social determinants of health, technology infrastructure, and many other factors.
Behavioral Intervention for Adults With Autism on Distribution of Attention in Triadic Conversations: A/B-Tested Pre-Post Study
Authors: Tepencelik Onur Necip , Wei Wenchuan , Luo Mirabel , Cosman Pamela , Dey Sujit
Published: August 2024

Background

Cross-neurotype differences in social communication patterns contribute to high unemployment rates among adults with autism. Adults with autism can be unsuccessful in job searches or terminated from employment due to mismatches between their social attention behaviors and society’s expectations on workplace communication.

Objective

We propose a behavioral intervention concerning distribution of attention in triadic (three-way) conversations. Specifically, the objective is to determine whether providing personalized feedback to each individual with autism based on an analysis of their attention distribution behavior during an initial conversation session would cause them to modify their orientation behavior in a subsequent conversation session.

Methods

Our system uses an unobtrusive head orientation estimation model to track the focus of attention of each individual. Head orientation sequences from a conversation session are analyzed based on five statistical domains (eg, maximum exclusion duration and average contact duration) representing different types of attention distribution behavior. An intervention is provided to a participant if they exceeded the nonautistic average for that behavior by at least 2 SDs. The intervention uses data analysis and video modeling along with a constructive discussion about the targeted behaviors. Twenty-four individuals with autism with no intellectual disabilities participated in the study. The participants were divided into test and control groups of 12 participants each.

Results

Based on their attention distribution behavior in the initial conversation session, 11 of the 12 participants in the test group received an intervention in at least one domain. Of the 11 participants who received the intervention, 10 showed improvement in at least one domain on which they received feedback. Independent t tests for larger test groups (df>15) confirmed that the group improvements are statistically significant compared with the corresponding controls (P<.05). Crawford-Howell t tests confirmed that 78% of the interventions resulted in significant improvements when compared individually against corresponding controls (P<.05). Additional t tests comparing the first conversation sessions of the test and control groups and comparing the first and second conversation sessions of the control group resulted in nonsignificant differences, pointing to the intervention being the main effect behind the behavioral changes displayed by the test group, as opposed to confounding effects or group differences.

Conclusions

Our proposed behavioral intervention offers a useful framework for practicing social attention behavior in multiparty conversations that are common in social and professional settings.