bluuebunny/crossref_metadata_2025 huggingface dataset:
Integration and Cointegration of Apartment Prices on the Primary and Secondary Market in Szczecin in the Years 2006-2022
Authors: Doszyń Mariusz
Published: December 2023

The objective of the paper is to verify hypotheses regarding integration and cointegration (relation) of mean apartment prices on the primary and secondary market in Szczecin. Both transaction prices as well as offer prices of apartments were investigated. The analysis period encompasses the years of 2006 – 2022 (quarterly data). An ADF test was employed to examine the integration of time series, taking into consideration a deterministic component in the form of a quadratic function. Only the time series of mean offer prices and transaction prices on the primary market proved to be integrated in the first degree. The time series of mean offer prices and transaction prices on the secondary market were not integrated, they occurred to be trend stationary series. A two-step Engle-Granger test was employed to analyze the cointegration of time series, which confirmed the cointegration of mean offer prices and transaction prices on the primary market. The relations between individual price types were examined with the use of a procedure which entailed analyzing (with an ADF test) difference stationarity between prices. From the empirical studies it arises that, in Szczecin, transaction and offer prices on the primary market follow one another. On the secondary market, offer and transaction prices are trend stationary and they converge. On the other hand, prices on the primary market diverge from prices on the secondary market (the primary market diverges from the secondary market). This concerns both offer prices as well as transaction prices.
The Phenomenon of the Polish Warehouse Real Estate Market – Sources of Success and Prospects for Development
Authors: Budner Waldemar W.
Published: December 2023

The article presents the development of the modern warehouse real estate market in Poland (from 2004 to 2022). The reference area is the European market. Against its background, Poland has become a fast-growing bank next to Germany and the fifth largest in terms of modern warehouse space. This happened despite the unstable and unpredictable macroeconomic and political situation in recent years, as well as the dangerous epidemic effects, e.g. connecting supply chains. The article is an attempt to find the sources of success of this Polish phenomenon, the search for a specific spatial configuration of the market and short- and long-term perspectives for the development of the warehouse market in Poland.
SISTEM ZA REVERZNU PRETRAGU SLIKA
Authors: Mršulja Ivan
Published: December 2023

Ovaj rad predlaže alternativni pristup reverznoj pretrazi slika korišćenjem modela mašinskog učenja za izvlačenje tagova i svojstava iz slike. Svođenjem vektorske pretrage na pretragu teksta, predloženi metod povećava efikasnost i tačnost pretrage slika.
RAZVOJ I POSTAVLJANJE BLOKČEJN-BAZIRANOG DISTRIBUIRANOG SISTEMA ZA OCENJIVANJE STUDENATA
Authors: Ignjatijević Aleksandar
Published: December 2023

U ovom radu će prvo biti predstavljeno istraživanje na temu Hyperledger Fabric blokčejna, a zatim osnove privatnih blokčejnova, kao i razvoj jedne takve mreže i njeno postavljanje. Pošto je akcenat rada na blokčejn i postavljanju istog, biće predstavljen razvoj Hyperledger Fabric mreže kao i postavljanje iste uz pomoć Kubernetes-a.
IMPLEMENTACIJA PARALELNOG K-MEANS ALGORITMA ZA KLASIFIKACIJU CIFARA UPOTREBOM OPENMP I MPI BIBLIOTEKA
Authors: Tanović Anja
Published: December 2023

U ovom radu prikazan je razvoj paralelnog k-means algoritma za klasifikaciju cifara. Opisan je osnovni k-means algoritam klasterizacije, kao i njegovo prilagođenje na algoritam za klasifikaciju skupa slika. Analizirane su mogućnosti paralelizacije algoritma i implementirane su različite verzije paralelnog k-means algoritma korišćenjem OpenMP i MPI biblioteka.
POWER-SIGNAL INTEGRITY SIMULACIJE ELEKTRONSKIH KOLA
Authors: Spajić Milomir
Published: December 2023

U radu je opisan teorijski uvod u Signal Integrity i Power Interity problematiku. Glavni akcenat bio je na izvršavanju Power Integrity simulacija koje se koriste za verifikaciju projektovanih štampanih ploča prije njihove izrade, što omogućava izbjegavanje potencijalnih problema nakon što se pločice izrade.
ГЕНЕРИСАЊЕ АРХИТЕКТОНСКИХ ОСНОВА УЗ ПОМОЋ МОДИФИКОВАНОГ ГЕНЕТСКОГ АЛГОРИТМА
Authors: Ињац Милица
Published: December 2023

У раду је приказана једна модификација генетског алгоритма са применама у генерисању архитектонских основа, односно распореда и организације просторија у оквиру једне етаже стамбеног или пословног грађевинског објекта. У раду су посебно разматрани проблеми кодирања јединки, те имплементација оператора укрштања и мутације.
WEB APLIKACIJA ZA PRETRAGU WINDOWS LOGOVA
Authors: Čičković Anđela
Published: December 2023

Rad pruža pregled teorijskih osnova u oblast logova događaja na Windows operativnom sistemu. Takođe, u okviru ovog rada implementirana je i detaljno opisana aplikacija za prikupljanje, pretragu i filtriranje logova događaja unutar lokalne mreže.
Estimation of Net Percent Error in Radioiodine-131 Activity during Administration to Patients
Authors: Ali Javaid , Shah Shoab , Samad Abdul , Tariq Imadullah , Biradr Ghufran , Sohail Muhammad , Memon Irum , Gul Attia , Ahmad Israr
Published: December 2023

Background:
Radiation workers have reported that some errors during measurement of radioiodine-131 activities have been observed, which may result poor quality images, greater radioactive waste and financial burden in the hospital. The purpose of this retrospective study was to estimate the net percent errors in radioiodine-131 activities during administration to thyroid patients and give some fruitful suggestions to reduce such errors.
Methods:
We included180 random patients i.e. thirty for each advised activity of 3 mCi, 15 mCi, 20 mCi, 25 mCi, 30 mCi and 150 mCi in this study from January 2019 to June 2022. All the recommended activities were measured with CRC-25R dose calibrator. The percent difference in the measured & prescribed activities and percent difference in the measured & residual activities were estimated. Finally, the net percent errors in administered activities were measured for all patients.
Results:
The net percent error in recommended activities of 3 mCi, 15 mCi, 20 mCi, 25 mCi, 30 mCi & 150 mCi and administered activities were [6.73 (-32.7, 20.95) ± 11.15] %, [3.91 (-3.85, 8.77) ± 2.94] %, [3.63 (-2.39, 7.79) ± 2.51] %, [3.55 (-0.65, 10.67) ±2.6] %, [2.93 (-1.98, 6.78) ± 1.89] % & [0.88 (-1.04, 2.68) ±0.87] % respectively.
Conclusion:
This study concludes that the patients receive approximately 6.73%, 3.91%, 3.63 %, 3.55 %, 2.93 % and 0.88 % less activities than the aforementioned activities respectively. The net percent error in radioiodine-131 activities is not alarming, but needs to be adjusted in order to ensure high quality images and optimum dose delivery.
Der Personzentrierte Ansatz nach Carl R. Rogers – eine Utopie?
Authors: Kokta Kristina
Published: December 2023

Der vorliegende Artikel dient der Aufdeckung utopischer Gedankenkonstrukte im Personzentrierten Ansatz nach Carl R. Rogers. Basierend auf der leitenden Forschungsfrage: „Inwiefern weist der Personzentrierte Ansatz utopische Momente auf?“ werden die Ideen und Entwürfe Rogers’ einer eingehenden Betrachtung unterzogen. Dahingehend erfolgt eine Untergliederung des gesamten Ansatzes in drei Teilbereiche – in seine individuellen, pädagogischen und sozialen, politischen Theorien –, in denen Rogers verstärkt für Innovationen und Veränderungen auf der Basis humanistischer Ideale und Werte plädiert. Zu diesem Zwecke ist eine vorangehende, differenzierte Beschäftigung mit dem Begriff der Utopie für ein besseres Verständnis dieses Phänomens unentbehrlich. Abschließend erfolgt eine postmoderne Diskussion der personzentrierten (utopischen) Theorien, um die Implikationen des Rogerianischen Ansatzes bis in die heutige Zeit beurteilen zu können.
Personenzentrierte psychologische Diagnostik
Authors: Sinzinger Alexandra
Published: December 2023

Der Personenzentrierte Ansatz stellt ein Verstehen im inneren Bezugsrahmen in den Mittelpunkt und lehnt Bewertungen von außen ab. Psychologische Diagnostik scheint mit ihrem Einsatz von Testverfahren und dem äußeren Bezugsrahmen einer Normtabelle auf den ersten Blick das genaue Gegenteil zu sein. Stellt man jedoch die personenzentrierte Haltung (Wertschätzung, Empathie, Kongruenz) in den Mittelpunkt, um zu beurteilen, was personenzentriert ist und was nicht, so wird deutlich, dass psychologische Diagnostik personenzentriert sein kann.
Personzentrierte Psychotherapie im post-kommunistischen Rumänien
Authors: Palada Florentina , Niculescu Georgeta
Published: December 2023

In diesem Beitrag beziehen wir uns auf persönliche Erfahrungen während des kommunistischen Regimes, darunter auf die Atmosphäre, die damals geherrscht hat, und wie diese mit unserer persönlichen und professionellen Entwicklung als Personzentrierte Psychotherapeutinnen zusammenhängt. Wir beschreiben die Anfänge, Entwicklung und aktuelle Lage der Personzentrierten Psychotherapie in Rumänien und nehmen dabei Bezug auf den sozialen, politischen und psychologischen Kontext, insbesondere auf die gesellschaftlichen Bewertungsbedingungen mit ihrem über viele Jahre währenden Einfluss auf die Selbstentwicklung und die Werte in der rumänischen Bevölkerung. Abschließend reflektieren wir die Herausforderungen einer personzentrierten psychotherapeutischen Ausbildung, die ja egalitäre Beziehungen fördert, jedoch mit der kollektiven Vorstellung konfrontiert ist, dass PsychotherapeutInnen dem medizinischen Modell entsprechend als Experten Lösungen für verschiedene Probleme anbieten.
Front cover, Editorial information, Table of Content, Back Cover
Authors: Editor Journal
Published: December 2023

Jurnal Sains dan Kesehatan. 2015. Volume 1 Nomor 3.

Front cover, Editorial information, Table of Content, Back Cover
Front Cover, Editorial Information, Table of Content, Back Cover
Authors: Editor Journal
Published: December 2023

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TEKNIS OPERASIONAL PENGELOLAAN SAMPAH DI DESA NAGRAK DAN DESA CIANGSANA MENUJU TPST 3R
Authors: Muharam Gusni , Ruhiyat Ratnaningsih , Minarti Astari
Published: December 2023

Nagrak and Ciangsana Village located in Gunung Putri Sub-district, Bogor Regency, West Java. The area of Nagrak Village is 5.84 km2 and the area of Ciangsana Village is 8.62 km2. The level of waste service in both villages is 12%, the planned service level target at the end of the planning year 2032 is 100%. This planning data collection uses the SNI 19-3964-1994 method regarding data collection methods in operational technical planning for waste management. Sampling using the stratified random sampling method, the waste generation rate in Nagrak Village and Ciangsana Village is 2 liters/person/day with a total population of 51488 people from the two villages, the waste generation from domestic areas has 54% organic waste and anorganic waste has 46%. The waste generation from Non-domestic areas has 60% organic waste and anorganic waste has 40%. Organic waste is processed with Black Soldier Fly (BSF), anorganic waste is processed with the Refused Derived Fuel (RDF) method at TPST 3R Trisakti. The planning stage consists of short term (2022-2024) medium term (2025-2028) and long term (2029-2032). The cost budget plan includes investment, operational and maintenance costs with a total cost of Rp.59,424,025,515. The selected alternative is alternative I, which has a more economical and affordable cost budget for Nagrak Village and Ciangsana Village.
FAKTOR-FAKTOR KEBERTAHANAN HUNIAN KELUARGA AKIBAT STUDENTIFIKASI
Authors: Muhamad Wibi Rinaldhi  , Rahel Sitomorang  , He
Published: December 2023

Meningkatnya jumlah mahasiswa menyebabkan meningkatnya kebutuhan fasilitas penunjang kehidupan mahasiswa dan perubahan pola tata ruang. Studentifikasi adalah proses ketika mahasiswa mulai tinggal di daerah dekat kampus sehinggapenghuni lama berkurang karena proses migrasi masuk, di kawasan RW 09 yang terdiri dari 5 RT yaitu RT 01 sampai RT 05, menurut ketua RW 09 mengatakan bahwa hanya RT 05 yang memiliki rumah keluarga yang masih banyak bertahan yaitu 13 rumah dari 30 bangunan sedangkan di RT lain didominasi oleh kosan Maka dari itu penelitian ini akan mengidentifikasi hunian keluarga yang masih bertahan di daerah tersebut melihat kini kawasan tersebut sudah di dominasi oleh mahasiswa dan faktor faktor yang menyebabkan keluarga tersebut masih bertahan di kawasan. Metode yang digunakan adalah deskriptifkualitatif untuk memperoleh informasi yang lebih dalam, ada 13 keluarga dari 13 rumah yang dimana di dominasi oleh warga Jakarta/warga asli 61%. Secara fisik 100% informan mengatakan bahwa merekabertahan karena lokasi strategis dan akses yang mudah, secara sosial responden mengatakan bahwa rumah yang mereka huni bukan hanya terdiri dari 1 keluarga saja,melainkan 38% dihuni lebih dari 1 keluarga, serta interaksi sosial masyarakat yang terjalin baik karena hubungan yang terjalin lama 46% dan lama tinggal yang lebih dari 20 tahun 100% responden mengatakan harga lahan tinggi 62 % menyebabkan mereka memilih untuk bertahan.
Students' self-determination as a psychological resource for self-realization in the process of studying at a university
Authors: Plotnikova Elena Sergeevna , Borzova Tatyana Vladimirovna
Published: December 2023

The article presents a study of the possibilities of developing students' self-determination as a psychological resource for self-realization in the process of studying at a university. The object of the study was the phenomenon of self-determination. The subject of the study is the development of students' self-determination as a psychological resource for self-realization in the process of studying at a university. Using a theoretical analysis of approaches to the study of students’ self-determination in the learning process, the following components were identified: autonomy, self-expression, ability to self-government, meaningfulness of life, which formed the basis for the implementation of the psychological and pedagogical program as its components. The goal of the psychological and pedagogical program was to develop the components of self-determination as a psychological and pedagogical resource for the self-realization of students’ personality. The program was implemented with small groups of students of 15 people at meetings of the psychological club. The following methods were used as diagnostic research methods: “Self-determination test” by E.N. Aspen, modification of K. Sheldon’s self-determination scale; “Test of meaning in life orientations” D.A. Leontyev; test “Ability to self-government” N.M. Peysakhova. The calculation of Student's T-test for connected and disconnected samples was also applied. As a result of testing the program for the development of self-determination on the basis of the Center for Social Adaptation and Support of Psychological Health at the Federal State Budgetary Educational Institution of Higher Education "Amur State University named after Sholom Aleichem", statistically significant indicators of its effectiveness were identified, consisting in an increase in indicators of autonomy, self-expression, ability to self-government and meaningfulness of life in students participating in its implementation.
المرونة الاستراتيجية ودورها في تحقيق الرشاقة التنظيمية
Authors: سعيد أديـبة أسـعد , مـحــمــد هـكـار زكـي , يوسف گوللي ميـهڤان شريف
Published: December 2023

إن الهدف من هذا البحث هو بيان المرونة الاستراتيجية ودورها في تحقيق الرشاقة  التنظيمية، ولإجراء الجانب العملي تسعى هذه الدراسة بأختيار المديرية مرور في مدينة دهوك ميدانياً لإجراء البحث، وتم الأعتماد على المنهج الوصفي التحليلي، وكما استند البحث على تشكيلة من الفرضيات الرئيسية والفرعية التي تم اختبارها ميدانياً في المديرية المبحوثة ، ولغرض جمع البيانات تم الأعتماد على استمارة الاستبانة، ولتحليل البيانات قمنا باستخدام تشكيلة من الأساليب الإحصائية في برنامج (SPSS V.22) وذلك لتحليل علاقة الارتباط والتأثير ما بين متغيرات البحث. ومن أهم الأستناجات التي توصل إليها البحث هو وجود علاقة أرتباط ذات دلالة معنوية بين أبعاد المرونة الاستراتيجية والرشاقة التنظيمية، ووجود تأثير ذات دلالة معنوية للمرونة الاستراتيجية بأبعادها في الرشاقة التنظيمية في المديرية المبحوثة، ومن خلال الأستناجات، تمت صياغة عدد من المقترحات أهمها ينبغي على المديرية المبحوثة زيادة الاهتمام بالمرونة الاستراتيجية لما لها من دور في تعزيز الرشاقة التنظيمية.
Pembelajaran Sejarah Melalui Nilai-Nilai Kesenian Degung di Kelas X IPS 1 MA Negeri 2 Ciamis Tahun Ajaran 2022-2023
Authors: Maspuroh Pupu , Pajriah Sri , Suryana Aan
Published: December 2023

History learning materials are generally based on textbooks and use very little developer material. This is the background of this research regarding the use of material for developing Degung artistic values in learning history. To find out what are the values of Degung art and how to use Degung artistic values in learning history in class X IPS 1 MA Negeri 2 Ciamis. Qualitative research methods with literature and field studies include observation, interviews and documentation. Data analysis used is data reduction, data presentation and verification. The results of the research show that the values contained in Degung art are religious values, historical values, social values, ethical values, creative values and aesthetic values. The use of material for developing Degung artistic values in history lessons must be in accordance with the learning objectives adapted to the teacher's teaching style. After designing the RPP and adding material to the power point slides the use of developer material has been realized and it is very possible to use developer material. Obstacles such as readjustment of learning outcomes, the use of developer material is a new thing, time constraints and student responses which later as teacher educators try to deal with these obstacles so that the results are that the teacher is greatly helped by the presence of developer material and students are enthusiastic about learning.
Diagnosis of posterior laryngeal cleft in a newborn with multiple congenital malformations
Authors: Vasilyevna Fedina Natalia , Igorevna Petrova Valeria , Vladimirovich Dmitriev Andrey , Anatolyevich Gudkov Roman , Anatolyevna Terekhina Tatiana
Published: December 2023

The article describes a rare congenital malformation – laryngeal cleft in a newborn. Clinical manifestations are characterised by diverse non-specific symptoms in the form of dysphagia, cough, aspiration, and stridor. The severity of the condition is determined by the depth and degree of the defect and concomitant somatic and neurological pathology of the child. The article presents a clinical case of a Type 3 laryngeal cleft in a newborn with multiple congenital malformations and presents a diagnostic search for a cleft. At the age of 7 months, endoscopic suturing of the defect was performed, which allowed restoring enteral nutrition and normalizing the nutritional status of the child.
CHARACTERIZATION OF SYNTHESIZED SILVER NANOPARTICLES USING LEPIDIUM SATIVUM PLANT
Authors: Obaidellah Jilan , Ahmed Sabah A.
Published: December 2023

The biosynthesis of Silver Nanoparticles (Ag NPs) was achieved through the utilization of an extract derived from the plant Lepidium Sativum, commonly referred to as Garden cress. The current study was undertaken to examine the impacts of different concentrations of silver nitrate (AgNO3) (0.1, 0.15, 0.2, 0.25, and 0.3) on the properties of silver nanoparticles. A range of analytical techniques were utilized to examine the characteristics of the nanoparticles, encompassing energy dispersive X-ray (EDX), field emission scanning electron microscopy (FESEM), UV-visible spectrophotometry (UV-Vis), X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FTIR). The findings demonstrated and suggested that Lepidium Sativum represents a viable choice for the environmentally friendly production of silver nanoparticles. The UV-Vis spectra of the studied silver nanoparticles (Ag NPs) exhibited a significant level of absorption within the wavelength range of 430-460 nm. The most intense absorption peak, observed at 453 nm, was associated with a concentration of 0.25 mol.  The examination of the Field Emission Scanning Electron Microscope (FESEM) images has revealed that the concentration of the solution has a substantial impact on the size, morphology, shape, and orientation of the silver nanoparticles (Ag NPs). The Ag NPs exhibit a mostly spherical and semi-spherical form, with an average particle size ranging from 65 to 80 nm. Additionally, the X-ray diffraction (XRD) analysis revealed that the silver nanoparticles (Ag NPs) synthesized exhibit a high level of purity, consisting solely of silver atoms arranged in a face-centered cubic crystalline lattice structure. The particle size, as determined from the (111) peak, falls within the range of 25.31-67.28 nm. The EDX spectrum analysis indicated that the primary chemical constituent present in the samples was silver (Ag). The silver nanoparticles (Ag NPs) produced at different concentrations exhibited a distinct peak in the UV-Vis spectrum, demonstrating significant absorbance above 400 nm in the visible region and minimal absorption in the UV range. The measured energy band gap (Eg) ranged from 2.05 to 2.3 eV. In addition, the Fourier Transform Infrared (FTIR) spectra of silver nanoparticles (Ag NPs) at different concentrations did not exhibit any discernible peak throughout the monitored range. This observation implies that the silver nanoparticles that were produced using cress plant extract had a high level of purity.
Microwave assisted Synthesis and Characterization of Novel Acylhydrazoneoximes
Authors: Chavan Jotiram K. , Patil Raju M.
Published: December 2023

The present study deals with microwave assisted synthesis of novel acylhydrazoneoximes using para-substituted isonitrosoacetophenones and terephthalohydrazide. The compounds have been characterized by physicochemical and spectroscopic techniques. TheUV-Visible spectroscopy has been used for electronic excitation to characterize each of these new acylhydrazoneoximes. FTIR spectroscopy is used to conduct the functional group study. 1H and 13C-NMR spectroscopy, mass spectrometry has also been used.
Enhanced Production of Microbial Lipid from R. opacus using Bagasse Hydrolysate
Authors: Mahmood Zainab , Singh Lalit Kumar
Published: December 2023

One alternative to traditional fossil fuels is biodiesel. It has a negative impact on nutritional supply because it is mostly manufactured from vegetable oils. Due to the possibility that oleaginous microbe lipids (such as those produced by bacteria, fungi and yeasts) could serve as an alternative raw material for the synthesis of biodiesel, the biomass and lipid buildup of Rhodococcus opacus were examined in several environmental settings. The study's current objective is to use the Response surface methodology's central composite design (CCD) to discover the ideal values of specific variables. Rhodococcus opacus, an oleaginous bacterium, was subjected to a CCD design using independent variables such as inoculum ratio, nitrogen concentration and magnesium concentration. The response variable used for the analysis was lipid content. Regarding the experimental data's lipid content%, a polynomial with a second-order model yielded good results (R2 = 96, (P ≤ 0.01)). Rhodococcus opacus produced the best results in the trials with glucose and hydrolysate with biomass concentrations of 4.75 g/L and 4.55 g/L and lipid contents of 71.18% and 66.55% respectively at pH 7. Compared to the starting values prior to optimization, these demonstrate a boost in the lipid concentration and an enhancement in the lipid coefficient. This study further supports the viability of R. opacus as a variant for the generation of biofuel from readily available, low-cost biomass resources.
Studies on the Sonochemical assisted Oxidation Reaction of Potassium Iodide for Iodine Release using Ultrasound
Authors: Sivakumar Venkatasubramanian , Poorna Prakash R.
Published: December 2023

Ultrasound (US) application and sonochemical reactions in various environmental processes are gaining importance. In this regard, liberation of iodine obtained through oxidation of potassium iodide (KI) using US has been studied in the present work. This method finds wide application of oxidation process in various applications such as unit process reactions, synthetic chemistry as well as waste remediation. Process parameters such as time and ultrasound power have been investigated. Liberation of iodine from the reaction system has been analyzed using UV-Visible spectrophotometric method through iodometry. Maximum liberation of iodine was obtained using ultrasound (25 W, 20 kHz) for 30 minutes treatment with 10 ml of 16.6% KI solution. The study finds potential use in sonochemical based oxidation reactions and environmental processes.
Identification and Structural Characterization of Forced Degradation Impurities of Sacubitril by HRMS – Development and Validation of a Stability indicating RP-HPLC method
Authors: Gandhi Santosh Kumar , Mandal Badal Kumar
Published: December 2023

The current work identifies and characterises the stress degradation products of the anti-hypertensive drug sacubitril. The stability profile of sacubitril was evaluated under several stress settings including hydrolytic, oxidative, thermal and photolytic conditions in accordance with ICH recommendations. The degradation products of sacubitril were separated using reverse phase liquid chromatography and structural characterization was carried out using HRMS. The chromatographic separation was carried out by Reverse Phase-High Performance Liquid Chromatography (RP-HPLC) using a Fortis C18 column (150 mm X 4.6 mm; 5μm particle size) with mobile phase A (consisting of 0.1% TFA in Milli-Q water) and mobile phase B (100% Acetonitrile) in gradient mode. With a sample injection volume of 10μL, the mobile phase flow rate was 0.7 mL/min. A quadrupole time-of-flight (Q-TOF) mass spectrometer was used for the LC-MS analysis. Sacubitril is relatively stable in oxidative, thermal and photolytic conditions; however, considerable degradation was observed in acid, base and neutral hydrolysis. Three degradation products were identified and the structural characterization of these impurities was performed using the HRMS data and mass fragmentation. The proposed RP-HPLC method was robust, precise and specific in determining the impurity profile of sacubitril under different stress conditions.
Endoscopic criteria for early differential diagnosis of gastritis-like form of primary non-Hodgkin's lymphomas and gastric cancer: A prospective study
Authors: Lozovaia Valeria V. , Malikhova Olga A. , Tumanyan Armen O. , Gusarova Olga A.
Published: December 2023

Aim. To reveal and study basic endoscopic differential-significant criteria characterizing gastric-like form of primary non-Hodgkin's lymphoma (NHL) from adenocarcinoma and signet-ring cell carcinoma (SRCC) of the stomach.
Materials and methods. In the prospective study, based of Blokhin National Medical Research Center of Oncology in the period from 2019 to June 2023, 106 patients with gastritic-like forms of primary NHL, adenocarcinoma and SRCC of the stomach were analyzed. Complex endoscopic study included examination in the modes of white light, magnification, narrow-band imaging (NBI, BLI, LCI) was done.
Results. All patients were divided into three groups: MALT gastric lymphoma (38 patients, 35.8%), gastric adenocarcinoma (33 patients, 31.1%), and SRCC (35 patients, 33.1%). At MALT-lymphoma the tumor was localized in the antrum of the stomach (52.6%),adenocarcinoma and SRCC – in the body (45.5 and 60%). In the tumor structure in MALT-lymphoma of the stomach in 100% of cases multiple point areas of microdepressions and multicenter character of the lesion were determined. At adenocarcinoma – depressed area in the central part of tumor (45.5%), at SRCC – extended areas of microdepressions (51.4%) and multicentric character of lesions. At MALT-lymphoma the pit pattern in 63.2% is of "balloon" type, vascular – of tree-like type (84.2%). In adenocarcinoma the vascular pattern was of the loop-type (42.4%), in SRCC – of the corkscrew-type (74.3%). Demarcation line was observed only in adenocarcinoma (100%). At endosonographic study at MALT-lymphoma the tumor was coming from deep layers of mucous coat (100%), changes of regional lymph nodes (LN) were absent, at adenocarcinoma – from mucous membrane (100%), LN were not changed, at SRCC – submucous spread of tumor (100%), changes in LN (40%).
Conclusion. Complex endoscopic examination is necessary to improve the quality of endoscopic examination of malignant gastric-like tumors, to determine the depth of invasion and spread of the tumor process, to assess the regional lymph drainage.
Clinical and economic benefits of parenteral iron carboxymaltosate in patients with gynecological cancers: A retrospective observational study
Authors: Saevets Valeriya V. , Shamanova Anna Yu.
Published: December 2023

Background. Timely diagnosis and treatment of iron deficiency anemia in cancer patients affect the quality of life and the effectiveness of anti-tumor treatment. However, choosing a method for correcting anemia is imperative to achieve maximum efficiency and safety with the least financial costs.
Aim. To evaluate postoperative methods for treating iron deficiency anemia in patients with gynecological cancers based on a comparative analysis of the clinical and economic outcomes of intravenous iron carboxymaltosate and blood transfusions.
Materials and methods. A study of 125 cases of malignant neoplasms of the female reproductive system with a history of iron deficiency anemia was conducted. Study Group 1 included 85 patients with malignancies receiving 500–1000 mg of iron carboxymaltosate (ICM) intravenously; Group 2 included 40 patients with transfusion of packed red cells (PRC). Clinical and economic outcomes of methods for anemia treatment were analyzed.
Results. In Group 1, the maximum increase in hemoglobin level was observed from Week 2 of ICM treatment (median increase 1.3 g/dL) peaking by Week 9–10 (median increase 2.3 g/dL). In Group 2 the maximum increase in hemoglobin level was noted at Week 1 after PRC transfusion (median increase 2.1 g/dL), with a gradually decreasing hemoglobin level for 3 weeks after that. No side effects of ICM treatment were reported. In 7 (17.5%) patients, a pyrogenic reaction (hyperthermia) was reported after a blood transfusion. The median time from surgery to the beginning of anti-tumor treatment (radiation therapy, chemotherapy) in Group 1 was 19 days [17; 25] vs. 26 days [22; 30] in Group 2 (p=0.0021).
Conclusion. High-dose ICM therapy for iron deficiency anemia in patients with gynecological malignancies is cost-effective and shows a long-term clinical effect.
THE UNYIELDING POWER OF LOVE: CHRISTIANITY'S IMPACT ON SOCIAL WELFARE AND HEALTHCARE
Authors: BUTE Sorin
Published: December 2023

This article explores the revolutionary impact of Christianity on social and medical assistance, emphasizing the profound influence of Christian values in shaping society. The Church played a crucial role in establishing institutions to care for the vulnerable, laying the foundation for modern state social and medical assistance systems. Christianity's emphasis on love, compassion, and the inherent worth of every human life as image of God remains relevant and transformative in the modern world. The Church's continued role in society is essential, as these values cannot be formalized or reduced to secular concepts, but stem from a deep conviction in God's initial love for humanity. The article discusses the revolutionary impact of Christianity on social and medical assistance, asserting that these services were born within the Church out of love. Christianity introduced the value of love as a new commandment and emphasized the absolute value of the human person, leading to the establishment of institutions like orphanages, homes for the elderly, and hospitals. The "Epistle to Diognetus," a 2nd-century Christian writing, is highlighted as an early testimony of Christian values that set believers apart from the prevailing Roman Empire culture. The article also explores how Christianity shaped the concept of humanity and the dignity of the human person. The belief in the Incarnation and the Imago Dei elevated human worth, contributing to the development of human rights, compassion, and care for the vulnerable. Early Christian communities established hospitals, and monastic communities played a significant role in providing medical care. Moreover, the Byzantine Empire's contributions to healthcare and hospitals are examined, showcasing how Christianity integrated medical science with spiritual healing and emphasized compassionate care for the sick and vulnerable. In conclusion, the article emphasizes that the values of love and care for the vulnerable remain relevant and continue to shape modern society, with the Church's role in promoting these values remaining essential.
littérature féminine au Maroc : témoignage d’une condition et voix / voie pour l’émancipation
Authors: Benjelloun Omar , Zerrad Khaoula
Published: December 2023

L’écriture, pour la femme marocaine, a souvent été confrontée à des obstacles majeurs : une société foncièrement machiste, des traditions prioritairement patriarcales et un système implacablement étouffant pour la créativité féminine tous azimuts. La littérature se présente alors pour elles, longtemps victimes de discrimination, d’injustice, d’asservissement et d’exclusion, comme un défi leur permettant de lutter contre l’oppression, d’arracher leurs droits et jouir de l’émancipation.
De l’amour violent à sa violente déstructuration dans Amants, heureux amants… (1923) de Valery Larbaud
Authors: Montibeller Clara
Published: December 2023

Le recueil de nouvelles de Valery Larbaud Amants, heureux amants… relate les monologues intérieurs de ses protagonistes, Marc Fournier, Felice Francia et Lucas Letheil, d’habiles manipulateurs se glorifiant de leurs amours multiples et surtout malsaines. Avides de pouvoir et de destruction, ces trois dandys déplacent leur colère sur les femmes qu’ils côtoient et prennent un malin plaisir à les voir souffrir. C’est au déploiement de cette violence ainsi qu’à ses modalités stylistiques que cet article s’intéresse. Après avoir étudié la typologie des violences dans les rapports de force homme-femme, nous glisserons de la violence thématique à une violence tonale plus astucieuse : l’ironie. Aussi s’agira-t-il d’approfondir le parallélisme entre les véhémences fictionnelles des personnages et l’éclatement du texte de l’auteur, qui met ainsi en abyme la violence humaine.
J.R. Léveillé. Suite
Authors: Gauthier Guy
Published: December 2023

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Tribological Performance of Automobile Brake Pads by Using Metal Matrix Composites
Authors:   Mechanical Dept & DPCOE, Pune, D Patil Rohan , Karamkar Bhushan P. ,   Mechanical Dept & DPCOE, Pune, Janunkar Prof.Rajeshwar ,   Automobile Dept & DPCOE, Pune
Published: December 2023

In today's ambitious world, there's a growing demand for high-performance components that are strong yet lightweight, durable, and energy-efficient, especially in industries such as automotive, aerospace, military, and sports. Aluminum, known for its low weight and excellent dimensional stability, is a popular choice. It is often reinforced with materials like SiC (silicon carbide) and Ni-Gr (nickel-graphite) to enhance wear and temperature resistance, making it suitable for various automotive applications, including cylinder fins, heat sinks, and piston materials. Additionally, common filler materials like silicon nitride (Si3N4), boron carbide (B4C), boron nitride (BN), aluminum oxide (Al2O3), aluminum nitride (AlN), titanium carbide (TiC), and titanium oxide (TiO2) tend to exhibit better compatibility with aluminum when it is in alloy form. Composites, especially metal matrix composites made of aluminum, offer superior mechanical properties compared to traditional metals. These composites are characterized by high specific strength, low weight, hardness, and wear resistance. Unlike unreinforced alloys, metal matrix composites possess exceptional tribological properties, allowing them to effectively compete with conventional materials in various tribological applications. These aluminum particle-filled metal matrix composites are actively pursued across sectors, including aerospace and automotive, due to their improved physical and tribo-mechanical properties.
AS STEM E O PENSAMENTO COMPUTACIONAL: RESOLVENDO DESAFIOS DA VIDA REAL NO ENSINO SUPERIOR
Authors: Costa Maria Cristina , Martins Sandra Gaspar , Domingos António
Published: December 2023

A promoção da educação STEM (Science, Technology, Engineering, and Mathematics) tem sido cada vez mais defendida, não só para motivar os estudantes para estas áreas, mas também para os preparar para os desafios do mundo real. Em particular, tem sido recomendada para promover a aprendizagem da matemática, muitas vezes acusada de contribuir para o problema da insuficiência de licenciados em áreas relacionadas com as STEM. Por outro lado, o Pensamento Computacional é um processo cognitivo que pode ser aplicado num contexto STEM e que requer capacidade de resolução de problemas, assim como pode contribuir para a aprendizagem da matemática. Este artigo apresenta o projeto CarRace que foi implementado numa turma de matemática de alunos de engenharia informática, entre os anos letivos 2017/18 e 2021/22; dele participaram um total de 581 estudantes. Com uma metodologia qualitativa, seguindo um paradigma interpretativo, conclui-se que o projeto promoveu o Pensamento Computacional nos estudantes, num contexto de educação STEM. Os resultados obtidos mostram a importância de implementar este tipo de abordagem com estudantes do ensino superior, nomeadamente estudantes de engenharia.
ETNOMATEMÁTICAS EN EL CURRÍCULO GUATEMALTECO: UNA EXPERIENCIA
Authors: Galo Claudia María Lara
Published: December 2023

En el trabajo se comparte la experiencia personal de la autora en relación a las Etnomatemáticas desde que las conoció a inicios de los 80’s hasta la actualidad. Como docente en las aulas de secundaria de Guatemala, como formadora de maestros y también como escritora de libros de texto y diseñadora de material didáctico, se comparten vivencias y ejemplos, así como reacciones de los estudiantes y colegas. Se detalla cómo se logró integrar el Sistema Maya de numeración y las Etnomatemáticas en el Currículo nacional base de Guatemala en 2005 que orienta el trabajo de todas las instituciones educativas del país. Termina con la actualidad mostrando lo que hacen ahora los colegas en las aulas y el impacto de las Etnomatemáticas en la vida de los maestros y los estudiantes en 2023.
Rekonstruksi Mitologis dalam Novel Putri Cina Karya Sindhunata
Authors: Hidayat Arif , Rahayu Diana Tri
Published: December 2023

Dalam membaca novel Putri Cina karya Sindhunata dihadapkan pada dua persoalan yang membelit pikiran. Pertama, melihat novel ini sebagai novel yang memuat persoalan kehidupan dalam kurun sejarah hingga sekarang dalam usaha untuk mendelegitimasi sejarah. Persoalan pertama ini sudah saya pahami sebagai sebuah pesan dan pengetahuan yang dimunculkan di dalam karya sastra. Kedua, diharuskan untuk melihat gambaran persoalan masyarakat yang penuh dengan mitos. Mitos-mitos itu sendiri pun bermain bebas, juga meloncat-loncat dan masih dipercaya oleh masarakat Indonesia hingga kini.
Demokratisasi Pendidikan Islam dalam Kearifan Lokal Dayak Hapakat Basara dan Korelasinya dengan Alquran
Authors: Rumsiti Neneng
Published: December 2023

The urgency of equal distribution of education is a big challenge to be realized. One of the steps taken is to promote the democratization of education. A more specific scope is, for example, in the learning process that upholds equality of rights without any distinction. This study explores deeper related to the concept of democratization of Islamic education contained in the local wisdom of the Dayak hapakat basara in collaboration with the content of the Qur’?n, 3:159 is related to democratic values, namely the principle of deliberation. The type of research used is qualitative with a concept analysis approach. The concept in question is the democratization of education contained in hapakat basara and the Qur’?n. The results of this study indicate that (1) the values contained in the local wisdom of hapakat basara include the values of unity, peace, and humanity which are realized through a deliberation system by looking for a common solution to the problems faced; (2) in line with this, the Qur’?n, 3:159 also upholds the values of deliberation in resolving all matters as stated in the snippet of verse 159 wa-sh?wirhum f? al-amr; (3) the concept of this deliberation which was later adopted and adopted as a concept of democratization of Islamic education resulted in three things, namely in the learning process there must be an agreement between teachers and students, upholding the principle of justice, and prioritizing freedom of opinion as a characteristic of democratic learning.
Manajemen Pengorganisasian Program Bahasa Arab 1 Bulan di Lembaga Kursus Kampung Inggris
Authors: Nada Fiki Qotrun , Faradisa Afifah Shofia , Kholid Nur
Published: December 2023

Setiap lembaga memiliki cara tersendiri dalam mengelola program-program yang telah dibentuk, seperti program bahasa Arab 1 bulan yang ada di lembaga Al-Azhar Pare Kediri. Penelitian ini bertujuan untuk memberikan deskripsi mengenai manajemen pengorganisasian dalam program bahasa Arab 1 bulan di lembaga kursus Al-Azhar Pare, serta kelebihan dan kekurangan manajemen pengorganisasiannya. Peneliti menggunakan pendekatan penelitian kualitatif dengan metode deskriptif. Data-data yang relevan dengan tujuan penelitian dikumpulkan dengan teknik wawancara dan observasi. Setelah terkumpul, data dianalisis dengan teknik model Miles dan Huberman. Hasil penelitian yang telah dilakukan oleh peneliti menunjukkan bahwa manajemen pengorganisasian pada program 1 bulan di lembaga Al-Azhar memuat beberapa langkah atau proses, mulai dari tujuan lembaga Al-Azhar, penentuan dan pengklasifikasian kegiatan, pendelegasian wewenang, penetapan jumlah ustaz, struktur organisasi, serta monitoring dan reorganisasi. Selain itu, hasil penelitian juga memaparkan mengenai kelebihan dan kekurangan manajemen pengorganisasian dalam program bahasa Arab 1 bulan di lembaga kursus Al-Azhar Pare.
Each institution has its way of managing the programs that have been formed, such as the 1-month Arabic program at the Al-Azhar course institution, Pare Kediri. This study aims to describe organizational management, the advantages and disadvantages of organizing management in the 1-month Arabic program at the Al-Azhar course institution. The researcher uses a qualitative approach with descriptive method. The relevant data to the formulation of the problem was collected using interview and observation techniques. After collecting the data, they were analyzed using the Miles and Huberman model of analysis technique. The results of the study conducted by the researcher show that the organizational management of the 1-month Arabic program at the Al-Azhar course institution contains several steps or processes starting from the goals of the Al-Azhar institution, determining and classifying activities, a delegation of authority, determining the number of teachers, organizational structure, as well as monitoring and reorganization. In addition, the results of the study also describe the advantages and disadvantages of organizational management in the 1-month Arabic language program at the Al-Azhar course institution.
Efektivitas Pembelajaran Daring Mata Pelajaran Sejarah Kebudayaan Islam pada Masa New Normal di Madrasah Aliyah Negeri
Authors: Lilawati Emi , Sa'adah Lailatus
Published: December 2023

Pembelajaran daring pada mata pelajaran Sejarah Kebudayaan Islam merupakan sistem pembelajaran yang digunakan di masa pandemi COVID-19 dengan memanfaatkan aplikasi Zoom, grup WhatsApp, dan e-learning. Tujuan dari penelitian ini adalah untuk mengetahui proses dan efektivitas pelaksanaan pembelajaran daring pada mata pelajaran Sejarah Kebudayaan Islam di MAN 4 Jombang. Penelitian ini merupakan penelitian kuantitatif deskriptif. Populasi dalam penelitian ini adalah siswi kelas XI MIA 3 yang berjumlah 36 siswi. Sampel yang digunakan berjumlah 36 siswi, karena populasi berjumlah kurang dari 100. Metode pengambilan data yang digunakan adalah wawancara, angket, dan dokumentasi. Hasil penelitian menunjukkan bahwa proses pelaksanaan pembelajaran daring pada mata pelajaran Sejarah Kebudayaan Islam di MAN 4 Jombang menurut teori yang telah dikemukakan oleh Slavin berjalan efektif, dan bahwa pelaksanaan pembelajaran daring di masa new normal pada mata pelajaran Sejarah Kebudayaan Islam di MAN 4 Jombang berjalan sangat efektif.
Online learning in Islamic Cultural History is a learning system that used during the COVID-19 pandemic by utilizing Zoom applications, WhatsApp groups, and e-learning. The purpose of this study was to determine the process and effectiveness of the implementation of online learning on the subject of Islamic Cultural History at MAN 4 Jombang. This research is a descriptive quantitative research. The population in this study were students of class XI MIA 3, consisting to 36 students. The sample used was 36 students, because the population was less than 100. The data collection methods used were interviews, questionnaires, and documentation. The results showed that the implementation of online learning on the subject of Islamic Cultural History at MAN 4 Jombang according to the theory that had been put forward by Slavin was effective, and that the implementation of online learning in the new normal period in the subject of Islamic Cultural History at MAN 4 Jombang is very effective.