bluuebunny/crossref_metadata_2025 huggingface dataset:
Repressed Utopias vs. Utopian Repressions: Czech Countercultural Communal Living Arrangements in the ‘Normalization’ Era (1970–1989)
Authors: Tharp Martin
Published: January 2023

The present contribution aims to examine this specific historic ‘Second World’ phenomenon — the communal living arrangements attempted by counterculturally minded, predominantly working-class youth in post-1968 Czechoslovakia, often (though not exclusively) in the former German Sudetenland — as an instance of the potentials and limitations associated with an attempt at a ‘mobile commons’ in 20th-century state socialism. Not only is the legacy of the Czech communes (baráky) an insufficiently researched historical topic, but even further, the placement of this phenomenon between its reflection of the American communal-utopian tradition in its 1960s forms, the emerging critique of industrial modernity, the growth of 20th-century ‘civil-society’ concepts, and the ‘Cold War’ mobilities across the Iron Curtain (intellectual-cultural autarky versus forced political emigration) forms a highly fruitful starting point for wider considerations. Examination of the Czech countercultural communal-living attempts within the social framework of the ‘normalization’ order of the 1970s and 1980s — state repression, socialist modernity, anti-public familialism — finds that their character as communities of refuge, rather than as deliberate planned experiments, places them at a particularly unique angle to the utopian vs. antiutopian debates, indeed even calling into question the very premises of this opposition.
IMPROVEMENT OF THE MECHANICAL PROPERTIES OF MOBILE PLATFORM STAINLESS CONSTRUCTION ELEMENTS
Authors: SZCZUCKA-LASOTA Bożena , WĘGRZYN Tomasz
Published: January 2023

Stainless steel could be treated as the main material used to construct various means of transport, including mobile platforms and tank trucks. An austenitic steel known as 316L steel (1.4401) has high resistance to atmospheric corrosion, natural waters, water vapor, alkaline solutions, and acids, even at elevated temperatures. This steel is weldable, although it is also prone to various types of welding cracks. Many factors influence the quality and mechanical properties of a joint. The most significant of these is the appropriate selection of welding parameters, which should be determined precisely and separately for each type of sheet, depending on its thickness and geometric features. The aim of the present article is to study the influence of main TIG (Tungsten inert gas) welding parameters on the creation of proper joints used in the construction of mobile truck platforms or tank trucks. The proper selection of parameters enables the production of welds with good functional properties. A novelty of this article is the proposal to weld each layer of a thick joint with different parameters, which has an important influence on the mechanical properties of the joint. It is expected that the new material and technological solution will yield a joint with good corrosion resistance and increased mechanical properties. This is important in the responsible construction of means of transport, using the example of mobile platforms and tank trucks. Different tests verifying the properties of joints, including non-destructive testing, tensile strength tests, and fatigue tests, as well as a hardness probe, were applied.
INFLUENCE OF CHANGES IN THE WORKING TEMPERATURE OF FLEXIBLE COUPLINGS ON THEIR STIFFNESS CHARACTERISTICS
Authors: OPASIAK Tadeusz , MARGIELEWICZ Jerzy , GĄSKA Damian , HANISZEWSKI Tomasz
Published: January 2023

This article compares flexible couplings of the spider-type insert, and the tire-type insert. The influences of the volume and hardness of the elastomeric connector on the characteristics of this type of coupling, as well as the course of the change of the stiffness coefficient as a result of changes in the operating temperature, are presented. In drive systems, flexible couplings undergo very frequent changes within a wide range of operating temperatures, which causes a change in the dynamic parameters of the flexible couplings during operation.
HUMAN AS A MAIN RISK DRIVER: UNDECLARED DANGEROUS GOODS IN MARITIME TRANSPORT & AVIATION
Authors: MATERNOVÁ Andrea , MATERNA Matúš
Published: January 2023

Dangerous goods (DGs) not declared for transport as required by the regulations can give rise to risks, as they can endanger public safety or the environment. This study explains the risks posed by undeclared shipments by providing information about the most common undeclared DGs aboard aircraft and maritime ships, legal frameworks regulating the proper transportation of DGs, and key mechanisms for preventing the occurrence of undeclared DG shipments. This paper identifies the responsibilities of each stakeholder involved in the process of DG transportation. The main objective of this paper is to reveal human errors and dishonest techniques within the supply chain when DGs are transported by air and sea.
La dimensión urbana del monumento en Aldo Rossi. Imágenes de una postal de Adolf Loos = The Urban Dimension of the Monument in Aldo Rossi. Images from a Postcard by Adolf Loos
Authors: Ferrer Sala Manuel
Published: January 2023

ResumenEl texto analiza la comprensión de lo monumental en la construcción de la ciudad en la obra de Aldo Rossi, que inicia en su visita a Moscú en 1951 y que desarrolla con la lectura de la obra de Adolf Loos. La hipótesis que propone el estudio es demostrar que esta lectura de la arquitectura monumental en Rossi, y que en Loos encontramos en sus proyectos para Viena, entre 1909 y 1912, nos ayuda a entender la mirada sobre la ciudad que comparten estos autores, cuya construcción definen desde “otra” monumentalidad.AbstractThe text studies the presence of the monumentality in the city construction in the work of Aldo Rossi, which begins with his visit to Moscow in 1951 and has a continuity in his reading of the work of Adolf Loos. The hypothesis proposed by the study, is to demonstrate that this comprehension of monumental architecture in Rossi, that we find in the Loos projects for Vienna between 1909 and 1912, helps us to understand a view of the city that these authors share and whose construction they define from another kind of monumentality.
Delayed objectives: Rewriting modern architecture since 1900 = Objetivos postergados: reescribir la arquitectura moderna desde 1900
Authors: De la Vega de León Macarena
Published: January 2023

ResumenEl proceso de concepción, escritura y revisión de La arquitectura moderna desde 1900 podría ser objecto de un estudio interesante según William J.R. Curtis. Después de la publicación de la primera edición (1982), apareció una segunda (1987) con un prefacio y capítulo al final sobre la arquitectura reciente. En la tercera edición (1996), el contenido sufrió una revisión y expansión; una integración de nuevas investigaciones en su discurso narrativo sin precedentes en la historiografía de la arquitectura moderna. Aunque la arquitectura moderna de países fuera de Europa y los Estados Unidos ya aparecía en la primera edición, no es hasta la tercera que Curtis cumple con su objetivo de mostrar el significado de la arquitectura moderna en partes remotas del mundo. Este artículo presenta la historia de la escritura del libro y propone analizar los cambios introducidos como objetivos que Curtis cumplió con un retraso de quince años. AbstractThe process of the conception, writing and revising of Modern Architecture Since 1900 would make an interesting study, according to William J.R. Curtis. After the first edition published in 1982, a second edition appeared in 1987 with a preface and an addendum on recent architecture. In the third edition (1996), the content was massively revised and expanded; an unusual integration of new findings into the overall synthesis. Although modern architecture in countries outside of central Europe and the United States already appeared in the first edition of the book, it is not until the third that Curtis fulfilled the objective to show what modern architecture may mean in remote parts of a rapidly changing world. This essay presents the story of the writing of the book and reflects on the changes introduced in the third edition understanding them as objectives that Curtis achieved with a delay of fifteen years.
Rahn Contract Construction as Micro, Small and Medium Enterprises (MSME) Capitalization Solutions in the Halal Industry Sector
Authors: Rizki Darlin , Wijanarko Fauzuna Naufal , Murti Tridjoko Wisnu
Published: January 2023

Many players in the halal industry do not have access to formal finance. As a result, they do not have access to capital, their business does not develop, and gradually goes out of business. This article aims to develop the concept of financing with the Rahn contract scheme. So far, the Rahn contract is only understood as an agreement in a pawnshop to obtain a certain amount of loans for consumptive purposes. This article uses a type of literature review where data is obtained from a number of publications derived from journals, books, proceedings, review results, magazines or newspapers, and other sources that are considered informative. This article argues that the Rahn contract can be developed as a capitalization solution for halal industry business units in the micro, small, and medium sectors. It further suggests the development of the function of the Rahn contract as a business capitalization contract by issuing shares as Marhun for financing media. The capitalization model with this scheme is intended to develop collateral as a means of investment.
Phytoremediation Based Typha Latifolia Landscape Design Strategy For Lapindo Mud Land Recovery And Eco-Tourism Sidoarjo
Authors: Irmayani  , Fetindah Suci Putri , Komalasari Intan
Published: January 2023

Lumpur Lapindo adalah suatu peristiwa bocornya pengeboran gas bumi yang terjadi di kabupaten Sidoarjo. Kebocoran pengeboran gas bumi tersebut dilakukan atas kelalaian PT. Lapindo Brantas. Hal ini yang menyebabkan pencemaran tanah akibat logam berat seperti Cd, Hg, dan Pb sehingga berdampak buruk pada pertumbuhan tanaman atau tumbuhan. Bahkan semburan tersebut terus berlanjut hingga kini. Semburan lumpur dialirkan ke sungai porong untuk menghindari rusaknya tanggul yang tingginya lebih dari 10 m. Meski sudah banyak penelitian tentang upaya penyelesaian lahan terkena lumpur Lapindo tapi volumenya mengalami penurunan yang tidak signifikan. Solusi alternatif yang ditawarkan dalam penelitian ini dengan melakukan fitoremediasi menggunakan tanaman ekor kucing dengan konsep lanskap atau design yang dilakukan di lingkungan terbuka dengan penataan yang jelas dan memberikan nilai estetika. Tanaman ekor kucing ini sebagai agen fitoremediator yang mampu menurunkan kadar ion logam berat seperti kadmium (Cd) di dekat permukaan tanah. Metode penulisan karya ilmiah ini adalah deskriptif kualitatif. Data yang kami peroleh merupakan data primer dan data sekunder dari berbagai literatur kepustakaan yang berkaitan dengan permasalahan tersebut. Penulisan karya ilmiah ini bertujuan untuk memberikan solusi terkait lahan yang terkena lumpur lapindo melalui fitoremediasi. Lahan tersebut diharapkan dapat digunakan sebagai areal recovery eko-wisata di daerah Sidoarjo melalui strategi design lanskap karena memberikan peluang besar jika dapat dioptimalkan pemanfaatan lahan tersebut.
Incidencia de factores de riesgo asociados a embarazadas con diagnóstico de anemia que acudieron al C.M.I. Buenos Aires de Villa en el año 2019
Authors:   , Choque Güere Klinsmar Gregory
Published: January 2023

La anemia afecta a gran parte de las gestantes en cualquier etapa del embarazo la cual pone en alto riesgo la integridad de la mama y el bebe, este problema aumentada cuando está asociado a factores de riesgo Gineco-Obstétricos Y Sociodemográficos, el objetivo “Determinar la incidencia de factores de riesgo que estan asociados a la anemia ferropénica en las gestantes que acudieron al Centro de Salud Buenos Aires de Villa en el año 2019” estudio básico-observacional, descriptivo, cuantitativo, transversal, se realizará la revisión de historias clínicas para conocer la incidencia de los factores asociados al desarrollo de anemia en gestantes que asistieron al Centro de Salud Buenos Aires de Villa del año 2019. La población a estudiar está conformada por 551 mujeres gestantes del Centro de salud Buenos Aires de Villa en el año 2019, la técnica que se utilizará es la observación y se utilizará una ficha para recolección de datos.
Calidad del suelo y fracciones orgánicas de la materia orgánica influenciados bajo un escenario de cambio climático en cultivos de maíz y quinua
Authors:   , Medina Solano Marco Antonio
Published: January 2023

Actualmente, el déficit hídrico y desertificación de suelos son efectos del cambio climático, estas situaciones alteran la calidad del suelo, así como la cantidad y calidad de la materia orgánica del suelo. Por ello es necesario conocer la necesidad hídrica que demanda un cultivo para no afectar la cantidad de carbono en el suelo, las fracciones de materia orgánica y el rendimiento. La presente investigación evaluó contenidos totales de carbono orgánico del suelo y carbono de las fracciones físico-químicas de materia orgánica frente al déficit hídrico, esto mediante un contexto de cambio climático en cultivos de quinua y maíz. La investigación se desarrolló en la sede del Instituto Nacional de Innovación Agraria – INIA, Huancayo; para ello se recolectó muestras de suelo por cada cultivo a una profundidad de 0–0,1m donde se evaluó: producción de grano, contenido de carbono orgánico total (COT) y los contenidos de carbono en ácidos fúlvicos, ácidos húmicos, humina, carbono orgánico particulado (COP) y asociados a los minerales (COAM). Los resultados de caracterización química indican que varios elementos (MO, N, K, pH) no se ven influenciados por el déficit hídrico. Respecto a las fracciones químicas, se evidenció diferencias significativas en el contenido de ácido húmico y fúlvico en quinua y humina en maíz, en las fracciones granulométricas en cultivo de maíz no se presentó diferencias significativas, mientras en quinua se evidenció diferencias significativas en COT y COP. En conclusión, las características químicas, los contenidos de carbono en las fracciones químicas/granulométricas y el rendimiento de los cultivos evaluados se ven influenciados por el déficit hídrico en ambos cultivos.
Elucidation of the Molecular Basis and Cellular Functions of Vinculin-Actin Directional Catch Bonding
Authors: Campbell Sharon , Chirasani Venkat , Khan Mohammad , Malavade Juilee , Dokholyan Nikolay , Hoffman Brenton
Published: January 2023

The ability of cells and tissues to differentially resist or adapt to mechanical forces applied in distinct directions is mediated by the ability of load-bearing proteins to preferentially maintain physical linkages in certain directions. However, the molecular basis and biological consequences of directional force-sensitive binding are unclear. Vinculin (Vcn) is a load-bearing linker protein that exhibits directional catch bonding due to interactions between the Vcn tail domain (Vt) and filamentous (F)-actin. We developed a computational approach to predict Vcn residues involved in directional catch bonding and produced a set of associated Vcn variants with unaltered Vt structure, actin binding, or phospholipid interactions. Incorporation of these variants into Vcn biosensors did not perturb Vcn conformation, but reduced Vcn loading consistent with loss of directional catch bonding. Expression of Vcn variants perturbed the coalignment of FAs and F-actin and directed cell migration, establishing key cellular functions for Vcn directional catch bonding.
Needlescopic suturless repair of congenital inguinal hernia: A randomized controlled study
Authors: Shalaby Rafik Yousef , Ali Mohamed Abdelmaboud , Daboos Mohammad Alsayed , Ahmed Yousef Mohamed , Helal Ahmed Abdelghafar , Gamman Ibrahim Ahmed
Published: January 2023

Background: Many techniques have been published in the literature about laparoscopic treatment of congenital inguinal hernia [CIH]. Division of the sac, with suturing the peritoneal defect has been advocated by many authors. Others stated that peritoneal disconnection alone is enough. This study aimed to compare the results of needlescopic disconnection of CIH sac with or without peritoneal defect suturing as regards feasibility, operative details, recurrence rate, and postoperative complications.
Patients and Methods: This study has been conducted prospectively on children operated upon by needlescopic separation of hernia sac at its neck with or without peritoneal defect suturing over the Internal Inguinal Ring [IIR] in the period from January 2020 to December 2022.
Results: A total of 230 patients with 260 hernial defects were corrected by needlescopic disconnection with either suturing or without suturing of the defect. They comprised of 141 (61.3%) males, and 89 (38.7%) females. Their ages ranged from 0.5 to 12 years (mean=5.14 ± 2.79). Patients were distributed into group A (N=116 patients) and group B (N=114 patients). In sac separation and closure of the defect group A, the mean operative time was 27.98 ± 2.89 [Rang = from 20 to 30 minutes] for unilateral cases and 37.29 ± 4.68 [Range = from 25 to 40 minutes] for bilateral one, whereas in group B, the mean operative time was 20.37 ± 2.37 [Range=from 15 to 25 minutes] for one-sided and 23.38 ± 2.22 [Range =from 20 to 25 minutes] in two-sided cases.
Conclusion: Needlescopic separation of hernia sac with suturing of peritoneal defect and disconnection without suturing for pediatric inguinal hernia repair, are feasible, safe, and less invasive with no recurrence and outstanding cosmetic results. However, non- suturing of peritoneal defect gives significantly shorter operative time than suturing of peritoneal defect
Evaluation and mapping of precipitable water in Southeast Asia using ground-based and satellite data for solar energy application
Authors: Sabooding Rusmadee , Taweekun Juntakan , Fawzi Mas
Published: January 2023

This article presents column integrated precipitable water (PW) readings from a NASA satellite and fourteen sites of the Aerosol Robotic Network (AERONET). The Terra satellite was compared with that obtained from ground-based observations in the tropics. It was found that the PW from the MODIS aboard the Terra satellite and those obtained from ground-based observations were in good agreement, with a root mean square error (RMSE) of 4.27% and a mean bias error (MBE) of 0.03% for the monthly. Develop empirical model to estimate the PW using data from relative humidity (AIRS) and temperature (AIRS) of ambient air. The model was developed to determine the daily and monthly PW based on PW data obtained from these stations over a 5-year period (2012–2016) and it was then validated against independent data for the previous 4-year period (2017–2020). It can be seen that the monthly PW values calculated using the empirical model had a RMSE of 3.64%. Develop a model2 to allow users to estimate the PW, namely relative humidity (AIRS) and temperature (GLDAS Model) of ambient air. This model2 performs reasonably when tested against an independent data set with the root mean square error (RMSE) and mean bias error (MBE) of 9.30% and − 0.05%, respectively (daily) and 3.58% and 0.02%, respectively (monthly). This research presents PW resource maps generated with the Geographic Information System (GIS) by satellite-based data from the Terra satellite for the 21-year period (2000–2020) and from AIRS (relative humidity and temperature) for the nineteen-year period (2002–2020). According to the monthly PW maps, Southeast Asia's PW values are generally high during the wet season (May to October) and low during the dry season (November to April) and according to the annual PW map, areas near the sea have high PW.
Poor tibiofemoral congruity increases the risk of posterior cruciate ligament injury.
Authors: Wang De-ning , Zhang Ke-fan , Shi Hui , Du Chang-ling , Wang Xin
Published: January 2023

Background Studies suggest that posterior cruciate ligament (PCL) injury may be related to the anatomical morphology of the distal femur and proximal tibia.
Purpose In retrospectively, we studied whether there were differences in the morphology and correlation between the distal femur and proximal tibia between the PCL injury group and the age and sex matched PCL intact control group, and then found the risk factors for posterior cruciate ligament rupture.
Methods From January 2015 to August 2022, 98 male patients with knee injury or discomfort due to non-contact mechanism were selected in the posterior cruciate ligament rupture group (n=49) and the posterior cruciate ligament intact group (n=49) by MRI images and arthroscopy. The posterior tibial slope (PTS), intercondylar notch width (INW), bicondyle width (BCW), angle of intercondylar notch (AIN), tibial spine width (TSW), and tibial platform width (TPW) were measured on X-ray and MRI coronal images, and the notch width index (NWI) was obtained by calculating the ratio of the intercondylar notch width to the bicondyle width, and the ratio of the tibial spine width to the tibial platform width was calculated to obtain the tibial eminence width index (TEWI). The ratio of the tibial spine width to the intercondylar notch width was calculated to obtain the tibiofemoral consistency index (TFCI) to describe the matching between the tibial spine and intercondylar notch.
Results Univariate analysis showed that the posterior tibial slope, tibial spine width, tibial eminence width index, and tibiofemoral consistency index were lower than those in the posterior cruciate ligament rupture group (P < 0.05), and there was no significant difference in age, intercondylar notch width, bicondyle width, notch width index, angle of intercondylar notch and tibial platform width between the two groups (P > 0.05). Multivariate logistic regression analysis showed that the tibiofemoral consistency index was an independent risk factor for posterior cruciate ligament rupture (P < 0.05). The receiver operator characteristic curve (ROC curve) shows that the tibiofemoral consistency index has some predictive value for posterior cruciate ligament rupture, the area under the curve was 0.785, 95% CI (0.695, 0.875).
Conclusions The tibiofemoral consistency index is an independent risk factor for posterior cruciate ligament rupture, and has a certain predictive value for posterior cruciate ligament rupture, and the lower the ratio, the worse the match between the tibial spine and the intercondylar notch, and the higher the risk of posterior cruciate ligament rupture.
DFT study on molecular structure, spectroscopic properties, Hirshfeld surface and molecular docking reveals the potential of flavones based on experimental and theoretical investigations
Authors: Manaka A. , Uvarani R.
Published: January 2023

In the present investigation, theoretical study on molecular geometry, vibrational, pharmaceutical and electronic properties of 3,4,5,7-tetrahydroxyflavone (7THDFN) and 3,4,7,8-tetrahydroxyflavone (8THDFN) were carried out using various functional levels at 6-311 + + G(d,p) as basis set. The results of the optimized geometrical parameters are presented and compared with the experimental values. The harmonic vibrational frequencies were calculated and the computed FT-IR and FT-Raman spectra have been compared with the experimental data. The 1H and 13C NMR chemical shifts were calculated using Gauge Independent Atomic Orbital (GIAO) approach. As an outcome, we found a good agreement between the experimental and computational structural values for FT-IR, FT-Raman, and NMR spectra. The molecular frontier orbital analysis was used to determine the charge transfer interaction, chemical reactivity, and non-linear optical properties of the designed molecules at the PBEPBE level theory. In addition, the molecular electrostatic potential surface maps were plotted to determine the chemical reactivity and the intermolecular interactions of the bioactive molecules. All these theoretical and experimental calculations will help us to characterize the chemical or biological properties of the designed drug molecules. The molecular modeling programs were also performed to estimate the pharmaceutical activities of the flavone compounds against human breast cancer. Finally, the in vitro cytotoxicity of bioactive molecules against human MCF-7 cell lines measured in MTT assays.
Health Services Use After Covid-19 Infection in Persons With Non-communicable Diseases
Authors: Vieira Yohana Pereira , Caputo Eduardo Lucia , Rocha Juliana Quadros Santos , Duro Suele Manjourany Silva , Saes Mirelle de Oliveira
Published: January 2023

The COVID-19 pandemic has triggered several changes in health care service at all levels, the primary and specialized care services had to be restructured hampering longitudinal follow-up. Thus, this scenario led to impaired disease management of patients with non-communicable diseases (NCDs), worsening the clinical picture of their pre-existing disease. This study aimed to evaluate the use of health services after COVID-19 infection in persons with non-communicable diseases (NCDs). This is a cross-sectional study in the city of Rio Grande with individuals aged 18 or older, from the urban area of the city, who had a positive diagnosis of COVID-19 by reverse transcription followed by polymerase chain reaction (RT-PCR) from December 2020 to March 2021. Participants were asked if they attend any healthcare services after COVID-19 infection. Regarding exposure, participants were asked if they had a medical diagnosis of the following NCDs: systemic arterial hypertension (SAH), diabetes mellitus (DM), respiratory diseases (RD) and heart diseases (HD). Descriptive analyzes were carried out and the Poisson regression was used to verify associations, with robust adjustment of variance. The likelihood of using healthcare services among participants with NCDs was up to four times when compared to individuals without it. Specifically, participants with NCDs were 67% (95% CI 1.33; 2.11) more likely to use urgent and emergency services. When analyzed by specific NCDs, only HD was associated with emergency room and emergency care unit use (PR 2.14; CI95%1.30-3.54; PR1.70; CI95%1.31-2.20, respectively). An increased use of specialized services (i.e., cardiologist) is highlighted among individuals with at least one NCD (PR:3.77; CI95%2.97-4.80), SAH (PR:3.47; CI95%2.97-4.31) and DM (PR:3.87; CI95%3.11-4.81). People with NCD required more healthcare services after COVID-19 infection, regardless of their disease when compared to those without it.
Effectiveness of exercise rehabilitation from the hospital to the community in individuals with shoulder disorders: a study protocol
Authors: Jeong Minah , Moon Chang Won , Kim Young Wook , Jung Il-Young
Published: January 2023

Background

Rotator cuff injury (RCI) and adhesive capsulitis of the shoulder (ACS) are musculoskeletal disorders (MSDs) characterized by limited motion of the shoulder. As symptoms of MSDs worsen over time, constant management and exercise are necessary. We hypothesized that shoulder pain can be managed through full-cycle rehabilitation exercises. Therefore, the purpose of this study is to confirm the effect of full-cycle rehabilitation exercises by providing exercise education in the community after hospital exercise intervention in subjects with RCI and ACS.

Methods

This is the protocol for a prospective, randomized controlled trial. Sixty subjects with shoulder pain will be recruited from the rehabilitation clinics of an urban medical hospital. Then, subjects will be randomly allocated into two groups. The intervention group will underwent 12 weeks of rehabilitation exercises in both the hospital and community, while the control group will conduct home exercises for 4 weeks using videos provided by the researchers. The main outcomes will be the change in shoulder pain and score of activities of daily living from initial evaluation to 3 months. The secondary outcomes will be functional measurements, such as ROM and the Manual Muscle Test (MMT), Timed Up and Go test (TUG), 10-meter walk test (10MWT), and Berg Balance Scale (BBS) scores, and will include subject-reported outcomes at multi-time points up to 3 months after the intervention.

Discussion

This is a randomized controlled trial to study the effectiveness of full-cycle rehabilitation exercises for shoulder pain. The results of this study will determine whether exercise from the hospital to the community is effective in subjects with RCI or ACS and will present evidence for the proper community connection guidelines for sustainable rehabilitation.
Trial registration:
Assessment of the dynamics of bike-sharing for students’ mobility in Kigali City
Authors: Ntamwiza Jean Marie Vianney , Bwire Hannibal
Published: January 2023

Compared to other modes of transportation available today, bike sharing is favored in more than 800 cities for its low environmental impact. Members of the bike-sharing program can use bikes from any related bike-sharing network. Users get the advantages of the system without bearing the burdens of ownership. There have been four versions of bike-sharing used thus far. The application of smart cards is a relatively new innovation introduced in bike-sharing systems. The new innovation allowed for the beginning of data availability through Stations and it has facilitated data accessibility for researchers. But papers tracking the evolution of bike-sharing membership and activities are rare. In contrast, studies focusing on students' mobility are few and far between. Within the framework of bike sharing, the dynamics of bike sharing are discussed in the literature of this paper. This has been accomplished by keeping tabs on how many people used the system over time, since this provided important information about the system's functioning and might be used as a basis for allocating stations. Data from GuraRide, Kigali - Rwanda used in this study. And 10,073 bike-share trips taken between December 9, 2021 and May 30, 2022 were analyzed. Then, a GIS software was used to map the locations of stations and corridors, and Python software was used for statistical analysis. A random forest algorithm was used to assess changes in stations and corridors usage. The findings indicated positive variations among system users and stations usage.
Clinical spectrum of ear, nose and throat foreign bodies at a tertiary hospital in Zanzibar, Tanzania
Authors: Abraham Zephania Saitabau , Kahinga Aveline Aloyce , Khamis Khamis Omar , Liyombo Edwin
Published: January 2023

Objective: Presence of foreign bodies (FBs) in the ears and upper aerodigestive tract is a common encounter in children unlike adults in otorhinolaryngology practice. Such foreign bodies form a major part of emergencies that the otorhinolaryngologist needs to attend. The high prevalence in children can be attributable to the inquisitive nature of children and their tendency to explore the environment. This study was a cross sectional study that aimed to determine the clinical spectrum of such foreign bodies at the largest tertiary hospital in Zanzibar, Tanzania.
Results: In this study, there were more females, 56(58.9%) than males, 39(41.1%) with female to male ratio being 1.4:1. Children aged less than 10 years predominated in this study, 69(72.6%). The nose, 36(37.9%) and ear, 29(30.5%) were the commonest sites were foreign bodies lodged followed by the pharynx, 22(23.2%) and esophagus, 10(8.4%). Regarding types of foreign bodies, inorganic 49(51.6%) types predominated and were mostly coins 17(17.9%). Majority of foreign bodies were removed in less than 24 hours (53.6%) and complications were found in 29(30.5%) patients and being more with nasal foreign bodies. Majority of those with complications presented 24 to 72 hours post lodging of foreign bodies
Association between Controlling Nutritional Status Score and Severity of Coronary artery stenosis in elderly patients
Authors: Zhong Guofu , Chen Mingtai , Chen Junteng , Xu Mujuan , Han Yue , Chang Xiao , Men Ling , Wang Ling
Published: January 2023

Background
The Controlling Nutritional Status (CONUT) Score is a tool to evaluate the body nutritional state. We investigated whether the CONUT score was associated with the incidence of coronary artery disease (CAD) and the severity of coronary artery stenosis in elderly patients.
Methods
This study involved 3296 elderly inpatients undergone coronary angiography. A demographic and clinical profile, as well as a Gensini score, were collected. The CONUT score were evaluated by the score system. There was a correlation analysis, a multivariable logistic regression analysis, and an analysis of the receiver operating characteristic curve (ROC curve).
Results
Based on the quartiles of CONUT scores, 3296 elderly inpatients were divided into four groups. There were significant differences in the vessel of coronary artery stenosis among the four groups (P < 0.05). The CONUT score was significantly positively correlated with Gensini score (r = 0.416, p < 0.001). After we divided enrolled patients into four groups by Gensini score and degree of coronary artery stenosis, the CONUT score was closely associated with the severity of coronary artery stenosis. For multivariable logistic regression, the CONUT score was risk factors of incidence of CAD and process of atherosclerosis progression after adjustment for potential confounding factors. The AUCs were 0.807 (95% CI: 0.790–0.824) for CAD, 0.717 (95% CI: 0.692–0.742) for mild stenosis, 0.842 (95% CI: 0.824–0.861) for moderate stenosis and 0.887 (95% CI: 0.867–0.908) for Severe stenosis by receiver operating characteristic analysis.
Conclusions
The CONUT score confers a predict factor of CAD in elderly patients, which also indicated the prognosis value in atherosclerosis progression.
Measuring perceived, wished and actual knowledge of healthcare providers about pediatric palliative care: development and validation of an online questionnaire in Italy
Authors: Zanello Elisa , Vecchi Roberta , Zamagni Giulia , Biagi Maria Celeste , Bruno Irene , Cragnolin Elisa , Danielli Elisabetta , Paoletti Silvia , Rabusin Marco , Ronfani Luca , Valente Emanuelle Pessa
Published: January 2023

Background. There is a lack of validated tools to evaluate the healthcare professionals’ competences on Pediatric Palliative Care (PPC) and Pain Therapy (PT). The aim of this study is to document the development and validation of a questionnaire to assess perceived, wished and actual knowledge of healthcare workers on PPC/PT.
Methods. On the basis of the Italian Society for Palliative Care PPC Core Curriculum (CC) for physicians, nurses and psychologists, an online questionnaire was developed in four sequential steps. Construct validity, coherence of the instrument, and educational needs of participants were assessed after a field testing in a referral hospital, Northeast Italy.
Results. One-hundred-five respondents completed the online questionnaire, from January 1st to July 31th 2019. Findings showed high internal consistency for both scales of perceived and wished knowledge (⍺=0.95 and ⍺=0.94, respectively). Psychologists reported higher levels of self-perceived skills on psychosocial needs of child and family at the end of life (p=0.006), mourning (p=0.003) and ethics and deontology in PT/PC (p=0.049). No differences were found by profession in terms of wished knowledge. Regarding actual knowledge assessment psychologists provided the bigger number of correct answers (p=0.022).
Conclusions. The questionnaire showed promising psychometric properties as a multidisciplinary instrument to measure health professionals’ knowledge on PPC/PT. Our findings suggest a need of continuous training in this topic and present possible content to be addressed by decision makers when organizing future training programs and/or educational events.
A Novel Differentially Expressed Cuproptosis-Related lncRNAs Signature to predict the prognosis and immune characteristics of hepatocellular carcinoma
Authors: Yin Chunlin , gao ming , sun yuansong , li he , zheng xianxian
Published: January 2023

Objective: According to a growing body of research, long non-coding RNAs (lncRNAs) participate in the progress of hepatocellular carcinoma (HCC). Cuproptosis is a distinct kind of programmed cell death, separating it from several other forms of programmed cell death that may be caused by genetic programming. Consequently, our aim was to investigate the relationship between Differentially Expressed Cuproptosis-Related lncRNAs (DECRLs) and clinical outcome and immune characteristics of HCC.
Method: The Cancer Genome Atlas (TCGA) database was used to retrieve related data. The GSE101728 dataset was downloaded from the Gene Expression Omnibus (GEO) database. A list of cuproptosis-related genes (CRGs) was obtained from a recently published article in Science. Combined analysis of TCGA dataset and the GSE101728 dataset identified differentially expressed CRGs(DECRGs).We can obtain DECRLs via co-expression. Then, using DECRLs, we developed a risk prediction model using Cox regression analysis and the least absolute shrinkage selection operator (LASSO) regression analysis. To evaluate the diagnostic accuracy of this model, a Kaplan-Meier (K-M) survival analysis and a receiver operating characteristic (ROC) curve analysis were used. Next, principal component analysis (PCA) was carried out.Moreover, the relationships between the risk model and immune characteristics, somatic mutation, and drug sensitivity were also investigated. Finally Real-Time quantitative PCR(RT-qPCR) and Western Blot confirmed the expression of DECRGs or DECRLs in HCC.
Results: Three high-risk DECRLs(AL031985.3,AC107959.3,MKLN1-AS) that can guide HCC prognosis and immune microenvironment were obtained through cox regression analysis.Immune functions such as APC co-inhibition,Type-II-IFN-Reponse,Parainflammation,MHC-class-I, and Tumor Immune Dysfunction and Exclusion(TIDE) score, and Tumor Mutation Burden(TMB) were significantly different in high-risk and low-risk groups.Moreover, this research also found that the IC50 values for 87 chemotherapeutic drugs varied widely across patients within high and low-risk groups.The expression of GLS at both mRNA and protein levels was significantly raised in HCC,and that of CDKN2A was dropped in HCC. The mRNA expression level of AL031985.3,AC107959.3 and MKLN1-AS was upregulated in HCC.
Conclusion: The proposed 3-DECRLs that can predict clinical prognosis or guide the immune characteristics and drugs that may have a potential curative effect on HCC received in our research may play a major role in patient management and immunotherapy.
Sleep-Disordered Breathing and Nocturnal Hypoxemia in Chronic Thromboembolic Pulmonary Disease
Authors: Li huiting , Yuan Ping , Jiang Rong , Zhao Qin-Hua , Sun Yuan-Yuan , Zhang Jian , Gong Su-Gang , Li Jin-Ling , Qiu Hong-Ling , Wu Wen-Hui , Luo cijun , Xu Jiang , Wang Lan , liu Jin-Ming
Published: January 2023

Background
Although sleep-disordered breathing (SDB) and nocturnal hypoxemia were known to be present in patients with chronic thromboembolic pulmonary hypertension (CTEPH), the difference of SDB and nocturnal hypoxemia between patients who have chronic thromboembolic pulmonary disease (CTEPD) with or without pulmonary hypertension (PH) at rest remain unknown.
Methods
Patients who had CTEPH (n = 80) or CTEPD without PH (n = 40) underwent sleep studies from July 2020 to October 2022 at Shanghai Pulmonary Hospital were enrolled. Nocturnal mean SpO2 (Mean SpO2) < 90% was defined as nocturnal hypoxemia, the percentage of time with a saturation below 90% (T90%) exceeding 10% was used to evaluate the severity of nocturnal hypoxemia. Logistic and linear regression analyses were performed to investigate the difference and potential predictor of SDB or nocturnal hypoxemia between CTEPH and CTEPD without PH.
Results
SDB was similarly prevalent in CTEPH and CTEPD without PH (p = 0.104), both characterized by obstructive sleep apnea (OSA). Twenty-two CTEPH patients were diagnosed with nocturnal hypoxemia, whereas only three were diagnosed in CTEPD without PH (p = 0.021). T90% was positively associated with mean pulmonary arterial pressure (mPAP) and pulmonary vascular resistance in patients with CTEPH and CTEPD without PH (p < 0.001); T90% was also negatively related with CO in these patients. Single-breath carbon monoxide diffusing capacity, sex and mPAP were all correlated with nocturnal hypoxemia in CTEPH and CTEPD without PH (all p < 0.05).
Conclusion
Nocturnal hypoxemia was worse in CTEPD with PH; T90%, but not SDB, was independently correlated with the hemodynamics in CTEPD with or without PH.
CaMKII promotes ROS-dependent apoptosis induced by Suilysin in PK-15 cells
Authors: Dai Shi-Xin , Zhao Qin , Xiao Hang , Lin Zhong-Sen , Du Sen-Yan , Wen Yi-Ping , Wu Rui , Yan Qi-Gui , Huang Xiao-Bo , Wang Yi-Ping , Lang Yi-Fei , Zhao Shan , Ma Xiao-Ping , Cao San-Jie
Published: January 2023

Background Activation of the multifunctional Ca2+/calmodulin-dependent protein kinase II (CaMKII) is a common intermediate of diverse stimuli-induced cell death. Suilysin(Sly) has toxicity on a variety of cells, however, the underlying mechanism of its effect remains unclear, and the mechanism of CaMKII in Sly-induced cell death has not been reported.
Methods CaMKII expression in porcine kidney-15 (PK-15) was detected by RT-qPCR analysis and Western blotting. Morphological analysis, and CCK-8 assay were done to verify that CaMKII promotes cytotoxicity induced by Sly. AO/EB staining, and flow cytometry were used to probe into the role of CaMKII and reactive oxygen species (ROS) in Sly-induced apoptosis. The effect of CaMKII on Sly-induced toxicity in mice was evaluated by pathological tissue slices analysis.
Results CaMKII was phosphorylated by Sly in PK-15, and inhibition or knockdown of CaMKII resulted in increased resistance to Sly. In PK-15 pretreated with a CaMKII inhibitor (KN93), Sly bound to the cell membrane was reduced, and the Sly-induced ROS, apoptosis were alleviated. Moreover, pretreatment with N-acetyl-L cysteine (NAC), a ROS scavenger, also blocked Sly-induced apoptosis. In summary, our study demonstrated that CaMKII activation and ROS production were involved in Sly-induced apoptosis. In addition, we identified that KN93 attenuated the damage of Sly to the viscera.
Conclusion CaMKII participates in Sly-induced ROS-dependent apoptosis and the toxic effects of Sly in mice.
Chronic pain patient narratives allow for the estimation of current pain intensity
Authors: Nunes Diogo A.P. , Ferreira-Gomes Joana , Oliveira Daniela , Vaz Carlos , Pimenta Sofia , Neto Fani , de Matos David Martins
Published: January 2023

Purpose
Estimate current pain intensity from personal narratives of the chronic pain experience and explore the linguistic differences that allow for it.
Methods
Chronic pain patients were interviewed, and demographic and clinical data were collected. Patients reported their current pain intensity on a Visual Analogue Scale (VAS), which was discretized into 3 classes: mild, moderate, and severe pain. Language features were extracted from the transcribed interview of each patient and used to classify their pain intensity category in a Leave One Out Validation setting. Performance was measured using the weighted F1 score. Possibly confounding variables were analyzed for internal validity.
Results
65 patients (40 females), averaging 56.4 ± 12.7 years of age, participated in the study. The best performing model was the Support Vector Machine with an Early Fusion of select language features, with an F1 of .60, improving 39.5% upon the baseline. Patients with mild pain focus more on the use of verbs, whilst moderate and severe pain patients focus on adverbs, and nouns and adjectives, respectively.
Conclusion
Pain intensity estimation is commonly based on facial expressions and various bio-signals, but language does not seem to have been previously used. We demonstrated a proof-of-concept for the analysis of the language of chronic pain in that context, and, importantly, that focus on specific words/themes is especially correlated with specific pain intensity categories. We show that language features from patient narratives indeed convey information relevant for pain intensity estimation, and that our computational models can take advantage of that.
Estimation of potato water footprint using machine leaning algorithms models in arid regions
Authors: Mohamed Amal , Abuarab Mohamed , Al-Ansari Nadhir , Sayed Hazem , Kassem Mohamed A. , Elbeltagi Ahmed , Mokhtar Ali
Published: January 2023

Precise assessment of water footprint to enhance water consumption and crop yields for irrigated agricultural efficiency is required in order to achieve water management sustainability. Although Penman-Monteith is more successful than others and is the most frequently used technique to calculate water footprint it requires a significant number of meteorological parameters at different spatio-temporal scales, sometimes inaccessible in many of the poor nations. Due to the greatest performance in the non-linear relations of inputs and output of the model, the complex hydrological phenomena are frequently described in machine learning models. Therefore, the objective of this research is to 1) develop and compare between the four-machine learning: Support Vector Regression (SVR), Random Forest (RF), Extreme Gradient Boost (XGB) and Artificial Neural Network (ANN) over three potato’s governorates (Al-Gharbia, Al-Dakahlia, and Al-Beheira) in Delta, Egypt and 2) select the best model in the best combination of climate input variables, which achieves high precision and low error in forecasting potato blue WF. The available variables for this study are maximum temperature (Tmax), minimum temperature (Tmin), average temperature (Tave), wind speed (WS), relative humidity (RH), precipitation (P), vapor pressure deficit (VPD), solar radiation (SR), Sown area (SA), and crop coefficient (Kc) to predict potato BWFP during (1990–2016). Six scenarios of input variables were used to test the weight of each variable in for four applied models. Different statistical indicators have been used to assess applied model performance (NSE, RMSE, MAE, MBE, A, R2, SI and MAPE). The results demonstrated that Sc5 with the XGB and ANN model is competent enough to evaluate BWF only if there are just vapor pressure deficit, precipitation, solar radiation, crop coefficient data followed by Sc1. The created models produced comparatively superior outcomes and can contribute to the decision-making process for water management and development planners.
BridgeCut: A New Algorithm for Balanced Partitioning of Signed Networks
Authors: Ehsani Maryam , Mansouri Reza
Published: January 2023

Structural analysis of signed networks is an important issue with many applications in the field of complex networks. In this context, balance theory is the main framework that leads naturally to partitioning balanced graphs into two parts with entirely positive edges in each part and only negative edges between them. However, real-world signed networks rarely have a perfectly balanced structure, and detecting near-balanced partitions can be formulated as an optimization problem with different objective functions. However, as an NP-Hard problem with many applications, different approaches have been proposed to it. Nevertheless, many methods ignore negative links and divide the graph into parts considering only positive edges. Emphasizing the importance of negative links and their properties in the partition scheme, we present a new approach, inspired by the Girvan-Newman community detection algorithm, called BridgeCut, in which the negative edges as the bridge set between the two parts are determined in a constructive algorithm. Sorted by edge betweenness, every negative edge is evaluated whether to be selected as a member of the bridge set or not, based on a balance improvement index. Analyzing the time complexity of this algorithm, it is implemented on some benchmark datasets and the results confirm its satisfactory performance. We further extend some measures to evaluate signed links' properties in relevance to their position and role in the whole structure.