bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Modified Dachengqi Decoction Soup on Retention of Intestinal Peristalgia in Patients with Hepatic Biliary Surgery
Authors: Huai De Lin
Published: July 2021

To evaluate the effect of Modified Dachengqi Decoction SoupÂ on retention of gastrointestinal motility in patients with hepatobiliary surgery after an enema. 100 patients with hepatobiliary surgery were randomly divided into group A and groupÂ B (n = 50). A group of postoperative parenteral nutrition, fasting and gastrointestinal decompression and other conventional treatment, B group on the basis of group A plus ModifiedÂ Dachengqi Soup retention enema, compared the two groupsÂ ofÂ gastrointestinal motility. The time of first exhaust, abdominal distension disappeared and bowel sounds recovered inÂ group B was significantly shorter than that in group A, whichÂ was statistically significant (P <0.05). There was no significant difference between the two groups (P > 0.05). The levelsÂ of motilin in group B were significantly higher than those inÂ group A at 2 days after the operation, and there was a significant difference between group A and group B, P < 0.05. TheÂ patients with hepatobiliary surgery can not only promote theÂ recovery of the postoperative organs, but also can significantly improve the level of motilin in the body, and thus improveÂ the patientâ€™s gastrointestinal motility.
Effect of Danshen Polyphenate Combined with Pelectin on Diabetic Pe- ripheral Neuropathy and Its Effects on Serum IGF-1, FFA and MBP
Authors: Xiaogang Bai
Published: July 2021

Objective: To observe the therapeutic effect of salvia miltiorrhiza phenylephrine combined with puerarin sodium on diabetic peripheral neuropathy (DPN) and the effect of serumÂ insulin-like growth factor 1 (IGF-1), free fatty acid (FFA) andÂ human myelin Protein (MBP). Methods: A total of 116 patients with diabetic peripheral neuropathy were randomly divided into observation group (58 cases) and control group (58Â cases). The control group was treated with sodium prostaglandin sodium. The observation group was treated with Danshephenolic acid Treatment, treatment for 8 weeks. The changesÂ of total symptom score system (TSS), vibration sensory threshold (VPT), ankle brachial index (ABI) and peripheral nerveÂ conduction velocity (NCV), serum IGF-1, FFA and MBP wereÂ observed before and after treatment.Â Results: The levels ofÂ numbness, tingling, burning, paresthesia and total score wereÂ significantly decreased in both groups after treatment, VPT,Â ABI and NCV wereÂ improved (P < 0.05), and the above indexes (P < 0.05). The levels of serum IGF-1 were increasedÂ and the levels of FFA and MBP were lower in the two groups.Â The improvement of the above indexes was better than that ofÂ the control group (P < 0.05). Conclusion: Salvia miltiorrhizaÂ polyphenate combined with puerarin sodium can significantlyÂ improve the vibration sensory threshold and ankle-brachial index, enhance the nerve conduction velocity and relieve clinicalÂ symptoms in patients with diabetic peripheral neuropathy. TheÂ mechanism may be related to the regulation of serum IGF-1,FFA, The level of MBP is relevant.
Efficacy and safety of rhubarb aconite decoction combined with acupoint application in the treatment of chronic renal failure (CRF)
Authors: Yang LI
Published: July 2021

Objective To study the efficacy and safety of rhubarb aconiteÂ decoction combined with acupoint application in the treatmentÂ of chronic renal failure (CRF). Methods 106 cases of CRF patients were randomly divided into two groups, the control groupÂ of 53 cases of conventional Western medicine treatment, theÂ treatment group of 53 cases of rhubarb aconite combined withÂ acupoint application, 2 groups were treated continuously forÂ 20 d. (UA), blood urea nitrogen (BUN) and endogenous creatinine clearance (Ccr) were measured before and after treatment.Â The levels of serum creatinine (Cr), serum creatinine (UA),Â blood urea nitrogen (BUN) and endogenous creatinine clearance (Ccr) were measured and compared. Level, and observeÂ the occurrence of adverse reactions during the two groups ofÂ treatment.
The Effect of Operating Room Detail Management in Improving the Safety of Operating Room
Authors: Huirong Yan
Published: July 2021

Objective: To study the method of improving the safety of theÂ operating room, and to explore the application effect of detailÂ management. Methods:Â The operating room of the hospital wasÂ used as a research object to study the effect of the operation roomÂ management in improving the safety of the operating room. InÂ August 2016, the operation room was strengthened and the detailsÂ of the operation room were collected. From June to August inÂ 2016, the incidence of surgical accidents in the operating room [1]Â was compared with that of patients who underwent surgeryÂ between August and October, and the satisfaction of patients andÂ their families for surgical care was compared. Results: TheÂ incidence of accidents in the operating room was significantlyÂ lower than that in August, which was significantly different fromÂ that before strength-ening the detailed management (P < 0.05).Â Conclusion: It is found that detailed management in the operatingÂ room has a positive effect on improving the safety of the operatingÂ room and can effectively reduce the accident rate in the operatingÂ room.
Application of Nursing Safety Management in Orthopedic Nursing Management
Authors: Fang Han
Published: July 2021

Objective: To analyze the application of nursing safetyÂ management in orthopedic nursing management. Methods: FromÂ January 2015 to December 2015, the Department of OrthopedicÂ Nursing Safety management measures, as well as January 2016 December 2016 during the period of our hospital for orthopedicÂ care safetyÂ management measures, the nursing work to sort out theÂ information Statistics, and the two measures before and after theÂ implementation of our hospital orthopedic care level and patientÂ care satisfaction were retrospectively summed up, and the value ofÂ the comparison. Results: After the implementation of orthopedicÂ nursing safety management measures, the nursing level of ourÂ hospital was obviously improved, and the patient â€˜s nursingÂ satisfaction increased significantly, the difference was statisticallyÂ significant (P<0.05).
Effect of STP on knowledge, attitude and practice of menopausal women regarding the prevention of cardiac disease and osteoporosis in selected health center of Kannur district
Authors: MV Shijina
Published: July 2021

Menopause is described as a period of psychological difficultiesÂ that changes the life style of women in multiple ways. MenopausalÂ women require more information about their physical andÂ psychological needs. Women who constitute half of worldÂ population. Identification of awareness and practice of menopausalÂ women aboutÂ menopausal complications is important factor whichÂ realized the investigators to conduct a study to assess the effect ofÂ structured teaching programme on knowledge, attitude andÂ practice of menopausal women regarding the prevention of cardiacÂ disease and osteoporosis in selected health center of Kannur wasÂ given and data wasÂ analyzed by using descriptive and inferentialÂ statistics.
Analysis of Causes and Treatment of Biliary Leakage after Hepatobiliary Surgery
Authors: Liu Hua
Published: July 2021

Hepatobiliary surgery is very common, and its operation is mainlyÂ based on the principle of human anatomy to carry out operations.Â In the actual operation, if there are no corresponding protectiveÂ measures, it is easy to damage bile tract and bile duct, even biliaryÂ leakage complications will be caused after the surgery, and aÂ certain effect will have on the patient's body and mind. It isÂ necessary to strengthen the prevention and treatment of biliaryÂ leakage on the basis of thinking on the causes of bile leakage, andÂ it can reduce the chance of the complications. Therefore, thisÂ article mainly focuses on strengthening the analysis and discussionÂ on the cause of biliary leakage after hepatobiliary surgery and theÂ treatment of related aspects.
Field Research on the Construction of Service Quality Evaluation Index for Professional Home Care
Authors: Ying Zhou
Published: July 2021

Objective: The purpose is to pinpoint the problems during homecare practice and identify the points and critical links of servicequality control. Method: The qualitative field research wasadopted. The three-month participatory observation wasimplemented to the home care practices performed by threecommunity health service centers in Shanghai. Then the collectedmaterials, including the field notes of nearly 100 thousand wordcount and pictures and images, have been sorted and analyzed.Result: The key factors that affect home care quality and thecritical links of quality control have been identified, namely,structure dimension, procedure dimension and result dimension,among which, structure dimension includes system, personnel,environment and equipment, etc., procedure dimension includeshealth assessment, basic nursing, nursing manipulation, emergencytreatment, health education and instruction, psychological nursing,hospice care and rehabilitation nursing, etc., and result dimensionincludes patient outcomes and nursing personnel outcomes, etc.Conclusion: This research unveils the true process of home careservice and the key factors that affect service quality, thusproviding firsthand information for the construction of a qualitycontrol index system for home care and in accord with nationalconditions.
Traditional Chinese Treatment (TCM) Progress of Urge Urinary Incontinence
Authors: Siyou Wang
Published: July 2021

Urge urinary incontinence is one of the common clinical symptoms ofparuria, which affects the physical and psychological health and lifequality of the patient seriously. TCM treatment on urge urinaryincontinence has significant advantages.
Collagen Hydrolysate Gly-Pro-Hyp on Osteoblastic Proliferation and Differentiation of MC3T3-E1 Cells
Authors: Min Geng
Published: July 2021

Objectives: Bone formation and bone resorption continuouslyoccur in bone tissue to prevent the accumulation of old bone, thisbeing called bone remodeling. Osteoblasts especially play a crucialrole in bone formation through the differentiation and proliferation.Therefore, in this study, we investigated the effects of collagenhydrolysate Glycine-Prolyl-Hydroxyproline (Gly-Pro-Hyp) onosteoblastic proliferation and differentiation in MC3T3-E1 cells.Methods: Four groups including control, Gly-Pro-Hyp 20 Î¼M,100 Î¼M, 500 Î¼M groups were set up in this study. Cells werecultured with blank control medium or Gly-Pro-Hyp of thedifferent dosages for 24 h. CCK 8 assay was analyzed cellproliferation. Assay of Alkaline phosphatase (ALP)activity wasanalyzed osteoblast differentiation. The expression levels of ALP,Col 1, Runx 2 and Osterix in MC3T3-E1 cells were measured byWestern blot. Results: The results indicated the treatment of Gly-Pro-Hyp promoted the proliferation of MC3T3-E1 cells andimproved ALP activity. In addition, cells treated with Gly-Pro-Hypsignificantly upregulated protein expression of ALP, type 1collagen, runt-related transcription factor 2 and osterix.Conclusion: The results demonstrate that Gly-Pro-Hyp promotedifferentiation inducement and proliferation of MC3T3-E1 cells,therefore may help to elucidate the transcriptional mechanism ofbone formation and possibly lead to the development of bone-forming drugs.
Simple Analysis on the Medical and Health Care Function of Tai Chi Chuan
Authors: Gaofeng Zhang
Published: July 2021

As the treasure of traditional culture in China, Tai Chi Chuanexercise is the crystallization of the wisdom and painstaking effortsof all previous generations with the civilization of the Chinesenation for thousands of years; it contains the principle ofcombining Yin and Yang and generation-inhibition in fiveelements with the beautiful appearance of martial artsperformances and a good health care function as well. In a word,Tai Chi Chuan has a distinct health care and therapeutic effect onhuman body with the knowledge of TCM guidance and health; it isa popular exercise from practice to theory, and it has been widelypromoted.
A Juvenile Sex Offender with Attention Deficit Hyperactivity Disorder
Authors: Chandradasa Miyuru
Published: July 2021

Background: Attention deficit hyperactivity disorder (ADHD) is aÂ neurodevelopmental disorder manifesting in early life. TheseÂ children are more vulnerable to sexual abuse as victims andÂ offenders. This is a case report of a teenager with previouslyÂ undiagnosed ADHD presenting with an alleged act of sexualÂ offending.Case report: According to the 14-year-old accused, he hasÂ engaged Â in Â penetrative Â anal Â intercourse Â with Â anotherÂ schoolmate. that similar past incidents had involved a teenage malerelative and insertion of foreign bodies to his anus repeatedly byÂ him. On assessment the accused had features of inattention, such asÂ difficulty in sustaining attention, failing to finish work and featuresÂ of impulsivity, such as difficulty waiting for his turn and intrudingÂ on others. He was diagnosed with ADHD according to DiagnosticÂ and Statistical Manual of Mental disorders (DSM 5) clinical criteriaÂ which were supported by the Sinhalese adaptation of the Swanson,Â Nolan and Pelham questionnaire. The assessment of the non-verbalÂ intelligence was in the normal range, but his school performanceÂ was far below the average.Discussion: Â Undiagnosed ADHD contributes to academicÂ impairment and inappropriate sexual behaviour. It is possible thatÂ the described adolescentâ€™s impulsiveness and inattention contributedÂ to his academic failure and risky sexual behaviour. Early detectionÂ and proper management of this disorder may have reduced the riskÂ of such behaviour in him.
Impact of Environment on Health: Nurseâ€™s Role
Authors: Vandali Vijayaraddi , Biradar Rekha B
Published: July 2021

ABSTRACT:Â Human life without environment is not at all possible, recent years due to huge urbanization and rise in technology affecting the health in a worst manner, ultimately we are only the responsible, Objectives :This article focuses to create awareness regarding environmental health problems. This article focuses on the issues, information to environmental health problems including sources of toxicants. The resources for nurses to prevent, minimize, to treat adverse environmental exposures. To draw attention of NGOs and Govt. There are many report (TOI) says that 70% of Indians doesnâ€™t breathe fresh air due to air pollution and not able to get safe drinking/adequate water its due to water pollution and major cause for this is huge increase in population, fastest growing urbanization. Heavy pollution occurred such air, water, food and huge chemicals using for growing crops also the main reason to reduce life-span as well as increase the risk of developing diseases. The nurse plays a pivotal role in prevention of environmental related risk and illness by continuous touch with the community peoples. The Nurse plays a pivotal role in prevention of health problems with regard to environment, primarily should have thorough knowledge about environmental impact in health and prevent. Â Nurse is foremost person who will assist in screening, diagnosis and alleviating health symptoms at the all the levels of health care.
Attitude of military students and military nurses towards spirituality and spiritual care
Authors: Asadzandi Minoo , Pourebrahimi Mohammad , Ebadi Abbas
Published: July 2021

Background and Purpose: Military nurses are exposed to various occupational stresses. Spirituality contributes to adaptation to critical situations and stresses. Spiritual care is an essential part of holistic care which in recent years has attracted the attention of health-related organizations. The aim of this study was to determine the attitude of military nurses, faculty members and military nursing students toward spirituality and spiritual care.Methods: In a cross-sectional descriptive study, 214 military nurses, faculty members and nursing students of Baqiyatallah University of Medical Sciences in Tehran were selected according to inclusion criteria by simple sampling method and completed the Spirituality and Spiritual Care Rating Scale [SSCR].Results: The mean score of attitude toward spirituality and spiritual care in clinical nurses was 69.4 [SDÂ±12.6] in nursing professors 74.6 [SDÂ±6.6] and in students 67.5] SDÂ±4/11]. The majority of the research community was at a high and desirable level. [Between 63 and 92, which was the maximum score of the questionnaire].Conclusion: The results of this study showed that military nurses, faculty members and nursing students of Baqiyatallah University of Medical Sciences in Tehran have a positive attitude toward spirituality. They tend to provide spiritual care. Therefore, it is necessary to provide a suitable platform for providing spiritual care.
An Investigation into the Needs of Community Health Service for Residents in Tianjin
Authors: Yan Guiming , Zhao Lin , Xia Li , Wu Jie , Sun Li
Published: July 2021

This article will investigate on the current needs of community service for residents in Tianjin city by providing nursing services at a targeted community. The demands for community nursing services in Tianjin city were investigated by sending questionnaire to targeted general residents and communities. As collected from the questionnaire, the most common diseases that were mentioned are Hypertension (33.2%), Coronary Heart Disease (27.8%) and Diabetes (15.7%). 63.0% of the residents have health records and 79.7% of the residents have seen a doctor in community hospitals. As results, the highest demands on general nursing services in the community are a regular physical examination, health consultations and regular home visits. Moreover, the control and management service demands specifically for chronic diseases are a regular heart rate examination, blood pressure examination, blood sugar examination, drug administration and a diet management. In conclusion, as the age structure of community is higher, a higher demand are needed in providing health services such as caring for chronic disease patients and geriatric, which is conducive in improving the quality and the satisfactory needs of health services for residents in Tianjin, China.
The Effect and Effectiveness Evaluation of Sit-up Training on Elderly Bedridden Patients with Severe Pneumonia
Authors: Chen Huashuang , Luo Yanling
Published: July 2021

ABSTRACTã€‘OBJECTIVE: To access the effect and the effectiveness of sit-up training on elderly bedridden patients with severe pneumonia. METHODS: A total of 150 elderly bedridden patients diagnosed with severe pneumonia were recruited for this study. They were divided equally into the observation group and control group i.e. 75 cases in each group. All patients were selected from January 2016 to April 2018. On this basis, both groups were treated with the same routine nursing care except with the addition of 30 to 60 minutes sit-up trainings twice daily for the control group under supervision. The clinical hospitalization outcomes, length of hospital stay, and patient care satisfaction of the two groups were compared. RESULTS: The clinical hospitalization outcomes, length of hospital stay, and patient satisfaction of the observation group were found to be superior to the control group, and the difference was significant. Conclusion: In bedridden elderly patients with severe pneumonia, sit-up training had positive effects and beneficial in improving the clinical outcomes and recovery rate.
GAMING DISORDER: A MINI REVIEW
Authors: Vandali Vijayreddy
Published: July 2021

ABSTRACT: Gaming disorder is defined in the draft 11th Revision of the International Classification of Diseases (ICD-11) as a pattern of gaming behavior (â€œdigital-gamingâ€ or â€œvideo-gamingâ€) characterized by impaired control over gaming, increasing priority given to gaming over other activities to the extent that gaming takes precedence over other interests and daily activities. For gaming disorder to be diagnosed, the behavior pattern must be of sufficient severity to result in significant impairment in personal, family, social, educational, occupational or other important areas of functioning and would normally have been evident for at least 12 months.
Effect of tripterine on Notch signaling pathway in IgA nephropathy rats
Authors: Liu Dan
Published: July 2021

Abstract: Objective: To investigate the effect of tripterine on Notch signaling pathway in renal tissue of IgA nephropathy rats. Methods: SD male rats were divided into the control group, IgAN nephropathy model group, benazepril group, 1mg/kg/d tripterine intervention group and 10mg/kg/d tripterine intervention group according to the random number table method, with 10 rats in each group. The urinary sediment and 24-hour urinary protein quantity were detected by conventional methods. The expressions of Notch1, Jagged1, Hes1 and Hey1 in renal tissue of rats were detected by real-time fluorescent quantitative PCR. Results: IgA nephropathy model was successfully established. The hematuria and proteinuria in model group were higher than those of control group (P<0.05). The expressions of Notch1, Jagged1, Hes1 and hey1 in kidney tissue of IgA nephropathy rats were significantly increased (P<0.05). Compared with the model group, hematuria and proteinuria in tripterine intervention group were alleviated. The expressions of Notch1, Jagged1, Hes1 and Hey1 in rat renal tissue were decreased (P<0.05). Moreover, the expressions of Notch1, Jagged1, Hes1 and Hey1 in renal tissue of rats in 10mg/kg/d tripterine intervention group were decreased (P<0.05). Conclusion: Tripterine can decrease the levels of hematuria and proteinuria in IgA nephropathy rats. The expression of Notch signaling pathway in IgA nephropathy rats is increased by the down-regulation of tripterine, suggesting that tripterine has a certain therapeutic effect on IgA nephropathy rat. And its role may be realized through this signal pathway so as to provide the new mentality for the diagnosis and treatment of IgA nephropathy.
Efficacy of carprostol tromethamine combined with mifepristone in the treatment of uterine fibroids
Authors: Wang Jun , Zhang Xian
Published: July 2021

ã€Abstractã€‘Objective: To investigate the clinical efficacy of carboprost tromethamine combined with mifepristone in the treatment of uterine fibroids. METHODS: A total of 66 patients with uterine fibroids admitted to our hospital between April 2018 and January 2019 were selected as subjects. According to the two different treatment methods, patients were divided equally. The observation group and the control group, each group of 33 people. The oxytocin drug treatment was medicated to the control group, and the prostaglandin tromethamine combined with mifepristone was medicated to the observation group. The treatment effect, adverse reaction, operation, and uterine muscle before and after surgery were observed in these two groups. Tumor tissue progesterone receptor and estrogen receptor levels. Results: The clinical treatment effect of the observation group was 93.94%, and the clinical treatment effect of the control group was 60.61%. The clinical treatment effect of the observation group was significantly higher than that of the control group; also the incidence of adverse reactions in the observation group in terms of rash, fatigue, nausea and vomiting was much lower than the control group, and could observe a significant difference. Finally in observation group, the amount of intraoperative blood loss, operation time and hospitalization time were better than those of the control group. The progesterone receptor and estrogen receptor levels in the uterine fibroid tissue after surgery should also be better than the control group, it is worth to make further comparison. Conclusion: Carprostol tromethamine combined with mifepristone is effective in the treatment of uterine fibroids and can be further developed.
Comparison of the Efficacy of Standard Decompressive Craniectomy Combined with Cerebrospinal Fluid Circulation Reconstruction in the Treatment of Severe Craniocerebral Injury
Authors: Han Zhanqing , Sun Jianbin , Zhong Jingyang
Published: July 2021

Abstractï¼š Objective: To observe and discuss the clinical effect of standard decompressive craniectomy combined with cerebrospinal fluid circulation reconstruction in the treatment of severe craniocerebral injury. Methods: Seventy patients who underwent surgery in our hospital were selected as subjects for this study. The time was from August 2016 to August 2018, and patients were divided into experimental group (35 cases) and control group (35 cases) according to the random number table method. The control group was treated with a single standard decompressive craniectomy according to clinical symptoms. The experimental group was treated with standard decompressive craniectomy combined with cerebrospinal fluid circulation reconstruction. The surgical treatment effect, GCS (Glasgow Coma Scale) score and operation time were compared between the two groups. Results: After comparison, the surgical treatment effect of the experimental group was higher than that of the control group and there was a significant difference between the two groups (P<0.05). The GCS score and operation time of the experimental group were also better than of the control group and there was a significant difference the two groups (P<0.05). Conclusion: The use of standard decompressive craniectomy combined with cerebrospinal fluid circulation reconstruction in the treatment of severe craniocerebral injury is more effective and worthy of widespread promotion and application.
Research progress of osteochondral composite scaffolds in tissue engineering cartilage repair
Authors: Zhao Zhongyi
Published: July 2021

Abstractï¼šRepair and regeneration of articular cartilage has always been a major challenge in the medical field due to its peculiar structure (e.g. sparsely distributed chondrocytes, no blood supply). Cartilage tissue engineering is one promising strategy for cartilage repair, however, one critical issue for cartilage tissue engineering is the integration between tissue-engineered and native cartilage. In recent years, osteochondral tissue engineering have attracted growing interest for overcoming this problem. Herein, we review the development of osteochondral tissue engineering. Firstly, currently used seed cells in osteochondral tissue engineering will be described. Secondly, several types of scaffolds and their (dis)advantage for osteochondral tissue engineering will be introduced. Thirdly, the growth factors currently used in osteochondral tissue engineering will be presented and discussed.
Analysis of factors influencing the complications of Solitaire AB stent mechanical thrombectomy in patients with acute intracranial artery occlusion
Authors: Zong Xin , Li Jingmei , Liu Shugai , Liang Qiuxia , Luo Xiaojun , Yan Bo , Guo Peng , Yang Dongrong
Published: July 2021

[Abstract] Objective: To investigate the influence factors of hemorrhage and stroke with retriever with Solitaire AB stent in patients with acute intracranial artery occlusion. Methods: A retrospective of 43 cases of patients with acute intracranial artery occlusion for endovascular treatment with Solitaire AB stent enrolled from March 2016 to June 2018 in our hospital, combining the characteristics of the patients of our city, through the clinical baseline data statistical analysis, complications screening of risk factors of complications. Results: There were 81.4% of patients who were dredged totally. The incidences of cerebral hemorrhage and infarction were 18.6% and 16.3%, cerebral hemorrhage group compared with control group, diabetes, blood pressure, revascularized time, NIHSS score, ASPECTS score had statistically significant differences, when infarction group compared with control group, age, opening time, ASITN_SIR score and grade of mTICI had statistically significant differences. Conclusion: Mechanical thrombectomy with Solitaire AB stent in patients with acute intracranial artery occlusion, the occurred of complications associated with various clinical factors, and the occurrence of complications seriously affect the prognosis of patients, therefore, selecting the indications strictly, and adopt individualized treatment to reduce complications.
Therapeutic Effect of Oral Administration and External Therapy of Traditional Chinese Medicine on Cervical Tuberculous
Authors: Yang Guoqiang , Zhang Jin
Published: July 2021

Objective: To analyze the clinical effect and value of oral administration and external therapy of traditional Chinese medicine for treatment of cervical tuberculous lymphadenopathy. Methods: A total of 56 patients with cervical tuberculous lymphadenopathy admitted to our hospital from January 1 to January 2018 were recruited. By using double-blind method, the patients were divided into control group (n=28) and experimental group (n=28). Control group comprised of patients with conventional anti-tuberculosis treatment, while the experimental group comprised of patients treated with oral administration and external therapy of traditional Chinese medicine. Total effective rate, incidence of complication and level of T lymphocyte subsets were compared between the two groups of cervical tuberculous lymphadenopathy patients. Results: Post-treatment data of total effective rate, complication rate, CD3+, CD4+, CD8+, CD4+/CD8+ of the experimental group were compared with the control group. P<0.05; statistical analysis showed statistical significance. Post-treatment data of CD3+, CD4+, CD8+, CD4+/CD8+ of both control and experimental groups were compared with pre-treatment data. P<0.05; statistical analysis showed statistical significance. Conclusion: Oral administration and external therapy of traditional Chinese medicine possesses significant effect in treatment of cervical tuberculous lymphadenopathy.
Core research on the clinical application value of dynamic CT perfusion imaging in stroke
Authors: Qin Tao , Zeng Yanni , Liu Liangjin , Dou Yongsheng , Xu Jia , Tang Heng
Published: July 2021

Objective: This study focused on the clinical application value of dynamic CT perfusion imaging in stroke. Methods: A total of 92 patients with stroke were enrolled in this study. All patients were selected from December 2017 to December 2018 according to different diagnostic methods. They were randomly divided into two groups: the observation group and control group. The number of patients in each group was 46. The observation group mainly used dynamic CT perfusion imaging for diagnosis while the control group mainly used CT plain scan. The diagnostic effects of the two groups of patients and the hemodynamic parameters of the surrounding area of sub-acute hematoma and the acute phase of stroke in the observation group were compared. Results: The clinical diagnosis of the observation group was 95.65% while the clinical diagnosis of the control group was 69.57%. The observation group was higher than that of the control group and the difference was significant. In addition, the hemodynamic parameters of the acute phase of the observation group and the sub-acute hematoma were also varied. Conclusion: Dynamic CT perfusion imaging has significant clinical value in stroke, and it is worthy of further application.
Arthroscopic minimally invasive surgery for knee joint gouty arthritis
Authors: Fan Yi , Zhang Cheng , Zheng Guotao , Wu Shuai , Wang Yujie , Bian Jinsong
Published: July 2021

Objective: To analyse the efficacy of arthroscopic minimally invasive surgery in patients with knee joint gouty arthritis. Methods: A retrospective analysis method was carried out on randomly selected 56 patients with knee gouty arthritis from early July 2018 to the end of June 2019. All patients underwent arthroscopic minimally invasive surgery. Results: In this study, the patients were followed for 10 months. The Lysholm score of knee function was found to be significantly higher after treatment compared to the scores before treatment (P<0.05). Conclusion: Arthroscopic minimally invasive surgery is a promising method to treat for knee joint gouty arthritis.
Clinical Effect of Qibai Landslide on Jellyfish Injuries in Qinhuangdao City
Authors: Li Huaian
Published: July 2021

Objective: To investigate the clinical effects of phlegm and phlegm and magnesium sulfate combined with magnesium sulfate in sea lice in Qinhuangdao City. Methods: A total of 78 patients with sea lice in Qinhuangdao City from June to

May 2018 were enrolled. They were randomly divided into control group (n=39 cases) and observation group (n=39 cases). The control group was treated with magnesium sulfate. The observation group was treated with Qibai Colshi Decoction on the basisof the control group. The effect of the patients was evaluated after 5 days of treatment. The disappearance time of symptoms, inflammatory factors and adverse drug reactions were compared. Results: After treatment, the onset, pain time, skin loss, swelling time and course of treatment were shorter in the observation group than in the control group (P<0.05). The levels of inflammatory factors were lower than those before treatment (P<5). The levels of TNF-a, IL-6, HIS and 5-HT in the observation group were lower than those in the control group (P<0.05). The rash, itching, drug allergy, liver and kidney were observed in the observation group and the control group. There was no significant difference in the incidence of dysfunction and blood pressure (P>0.05). Conclusion: The combination of magnesium sulfate and magnesium sulfate in the treatment of sea lice in Qinhuangdao City can shorten the disappearance of symptoms, reduce the level of inflammatory factors, and increase the incidence of adverse drug reactions. It is worthy of popularization and application.
Gene big data- A Research for Monogenic Hypertension Diagnosis
Authors: Wei Kuangyi
Published: July 2021

This paper designed a detailed procedure for monogenic hypertension diagnosis by Whole Exome Sequencing (WES) and provided reliable precise medication guidance. Identification of mutated points provides the clinician valuable information for effective individualized therapeutic option. Therapeutic options that specifically restore the pathway disturbed by these point mutations can be selected to give a precise medicinal guidance.
Efficacy and Safety of Tirofiban in Thrombolytic Therapy for Ischemic Stroke
Authors: Wang Ruixian , Yang Lishun , Zhang Jianhui , Yao Qingping , Zhang Zihuan
Published: July 2021

Objective: To evaluate the efficacy and safety of tirofiban hydrochloride in the treatment of ischemic stroke with thrombolytic therapy. Method: Two hundred patients with acute ischemic stroke thrombolysis were randomly divided into the experimental group and the control group. The experimental group was given tirofiban with the addition of rtpa in the control group and the therapeutic effects of the two groups were compared. Results: In comparison with the control group, the NIHSS improvement rate was 98% in the experimental group within 14 days. The platelet aggregation rate and efficacy in the experimental group were significantly reduced than the control group (P < 0.01). The major adverse reaction in the two groups was hemorrhage with an incidence rate of 3%. Conclusion: Tirofiban hydrochloride is a highly effective and selective platelet glycoprotein IIb/IIIa receptor inhibitor, which is safe and effective in combination with heparin and aspirin.
Comparative Study of Mechanical and Manual Compression in the Resuscitation of Patients with Out-of-hospital Cardiac Arrest
Authors: Han Bing , Hong Lan
Published: July 2021

Objective: To analyze the effect of mechanical and manual compression on the resuscitation effect of out-of-hospital cardiac arrest patients. Methods: The 40 trained medical personnel who are skilled in bare hand compression and cardiopulmonary resuscitation machines were divided into two groups with 20 people in each group. The control group consists of a bare hand compression group while the observation group consists of cardiopulmonary resuscitation group. The two groups of people performed heart compression on the simulated person and observe the effect of the two compression methods on the patient during the cardiac arrest operation. Results: The resuscitation success rate in the control group was 65%, the resuscitation success rate in the observation group was 90%. The systolic blood pressure, heart rate, blood oxygen saturation, the accuracy rate of compression depth frequency, and interruption time in the observation group (cardiac resuscitation compression group) were significantly better than the control group (bare hand compression group). Conclusion: The use of mechanical compression has a small error rate, a high success rate, saves time and effort, and can effectively help patients. It is worth promoting and applying.
Clinical Study on the Effects of Different Infusion Solutions on Colloid Osmotic Pressure During Major Abdominal Surgery and Perioperative Albumin in Elderly Patients
Authors: Zhao Chunyan , Chen Cibo , Xia Bingchun
Published: July 2021

Objective: To explore the effects of different infusion schemes on colloid osmotic pressure during major abdominal surgery and perioperative albumin in elderly patients. Methods: 140 elderly patients of 65-80 years old undergoing major abdominal surgery were divided into 4 groups according to the method of random number table , and different proportions of crystals and colloids were given to different groups (group A: whole crystal, group B: crystal-colloid ratio 1 : 1, group C: crystal-colloid ratio 2: 1, Group D: crystal-colloid ratio 1: 2).  The plasma colloid osmotic pressure and level of albumin during perioperative period were monitored. Simultaneously observe the arterial blood pH, blood glucose, extubating time of endotracheal tube, postoperative feeding time, et al. Results: The total amount of liquid inputted in the group of whole crystal was 3056ml (3056 ± 253), which was significantly increased compared with other groups (P<0.01). At the same time, the colloid osmotic pressure decreased by 11.9 mmHg (11.9 ± 2.8), which was more obviously decreased than that of the other groups( B group3.9 ± 1.3, C group 1.5 ± 0.3, D group 4.7±2.1). The difference was a statistically significant(P<0.01). On the other day after surgery, the level of albumin decreased by an average of 4.3 g / L (4.5 ± 1.9) compared with that in group B before surgery, and group C decreased by 2.9 g / L (2.9 ± 1.2) in average, which was significantly different (P<0.05) from group A 10.2 g / L (10.2 ± 1.8). There was no statistically significant difference between group A and group D (P>0.05). And the other indexes were not significantly different between the two groups. Conclusion: This study found that different infusion solutions with different crystal-colloid ratios had an effect on perioperative colloid osmotic pressure and level of albumin.
The Factors Affecting the Efficacy of ?-interferon in the Treatment of (CHB)
Authors: Lin Huaide
Published: July 2021

Objective:  To analyze the factors affecting the efficacy of ?-interferon in the treatment of chronic hepatitis B (CHB). Methods: A total of 100 patients with CHB treated in our hospital from June 2018 to June 2019 were selected. All patients were treated with ?-interferon to evaluate the efficacy, and the factors affecting the effect of ?-interferon on CHB were analyzed. Results: After treatment, 54 patients fully responded and 46 patients did not; the levels of white blood cells, HBV DNA, and HBsAg in the complete response group were lower than those in the incompletely response group, and the differences were statistically significant (P <0.05); Multivariate logistic regression analysis found that serum HBV DNA and HBsAg were independent factors affecting the efficacy of ?-interferon in the treatment of CHB (OR> 1, P<0.05). Conclusion: Serum HBV DNA and HBsAg are risk factors that affect the efficacy of ?-interferon in the treatment of CHB. Monitoring the changes of serum HBV DNA and HBsAg levels has important clinical significance for predicting the efficacy.
Analysis of Ultrasound-guided Ilioinguinal and Iliohypogastric Nerve Block in Tension-Free Inguinal Hernia Repair in Elderly Patients
Authors: Liao Qikai , Xie Dongmei
Published: July 2021

Objective: To explore the value of ultrasound-guided ilioinguinal and iliohypogastric nerve block (IINB) in tension-free inguinal hernia repair in elderly patients. Methods: A total of 70 elderly patients with tension-free inguinal hernia repair who treated in the hospital from April 2018 to November 2019 were selected and divided into two groups according to the random number table method, with 35 cases each. The control group underwent infiltration of local anesthesia(LA), and the study group added with IINB. The visual analogue scale (VAS) scores of the two groups of patients were compared. Results: The VAS score of the study group when pulling the hernia sac was lower than that of the control group, and the difference was statistically significant (P<0.05). Conclusion: IINB has good analgesic effect in tension-free inguinal hernia repair in elderly patients, and it is worth promoting.
Nurses Role in Prevention of HIV/AIDS
Authors: Vandali Vijayaraddi
Published: July 2021

Acquired immunodeficiency syndrome (AIDS) is a chronic, potentially life-threatening condition as per World Health Organization there are about 37.9 Million peoples living with AIDS/HIV in the world and out of which only 23.3 Million peoples accessing antiretroviral therapy but remaining are still not under treatment and such peoples may spread/transmit HIV more and rapid. Awareness is required among peoples living with HIV and high risk groups should consider on high priority. Nurses play key role in prevention of HIV/AIDS by significant functions such as health education to youths, high risk groups and eligible couples and prophylaxis. There is no treatment or vaccine not available to cure this syndrome, so for this deadly syndrome prevention is much better than cure is possible.
Transforaminal Endoscope for the Treatment of Thoracic Disc Herniation
Authors: Zeng Tenghui , Guo Daiqi
Published: July 2021

Objective: Transforaminal endoscope was used in the treatment of thoracic disc herniation and the therapeutic effect was discussed. Methods: Sixteen patients with thoracic disc herniation admitted to our hospital from October 2018 to May 2019 were divided into control group and observation group according to the random number table method, with 8 patients in each group. The control group was treated with posterior laminectomy approach, and the observation group was treated with transforaminal endoscope. The surgery-related conditions (intraoperative blood loss, surgery time, and postoperative drainage volume), VAS score, JOA score and postoperative complications were compared and analyzed. Results: There was no statistically significant difference between the two groups in the total effective rate and preoperative VAS score (P > 0.05). Compared with the control group, the observation group had shorter surgery time and incision length, less postoperative drainage volume, and higher VAS score 3 days after surgery, JOA score on day 7 after surgery, and JOA score 3 months after surgery, showing statistically significant differences (P < 0.05). There was no significant difference in the complications between the two groups (X2=1.067, P=0.833). Conclusions: Transforaminal endoscope had a good clinical effect with small incision and injury in the treatment of patients with thoracic disc herniation.
Application of Functional Exercise Nursing Plan Based on Evidence-based Nursing After Hip Replacement
Authors: Dong Rongrong , Chen Huaqin
Published: July 2021

Objective: To explore the effect of functional exercise nursing plan based on evidence-based nursing in patients after hip replacement. Methods: A total of 150 patients who underwent hip replacement in the orthopedic second ward of our hospital during the research period from January 2010 to January 2020 were selected as the research object. The random number expression method was applied to achieve grouping of patients. Among them, the control group received conventional rehabilitation treatment; the experimental group guided rehabilitation exercises according to the functional exercise nursing plan after hip replacement, and the rehabilitation conditions of the two groups were compared. Results: Compared with the patients in the control group, the bed time (7.45 ± 2.10) days and average hospital stay (15.84 ± 3.29) of the experimental group were relatively shorter. The incidence of complications in the experimental group and the control group was 6.67% and 16.00%, which are significantly different. The difference in Harris hip score before surgery was small, and the difference when discharge and after discharge was gradually increased, showing a better care effect in the experimental group. There was no significant difference in preoperative quality of life scores between the two groups before surgery (P > 0.05). The life quality of the experimental group was significantly higher than that of the control group at discharge, 1 month after discharge and 3 months after discharge, and showed most significantly after 3 months. Conclusion: The effect of functional exercise nursing plan based on evidence-based nursing in patients after hip replacement is remarkable, which can promote the recovery of patients, improve the quality of life, reduce the hospitalization time, reduce the incidence of postoperative complications, and has a positive significance in promoting clinical development in China.
Nursing Effect of Standardized Nursing Intervention in Endoscopic Examination of Patients with Gastric Ulcer Complicated with Diabetes
Authors: Hu Xue
Published: July 2021

Objective: To explore the nursing effect of standardized nursing interventions in endoscopic examination of patients with gastric ulcer complicated with diabetes. Methods: 90 patients with gastric ulcer complicated with diabetes who were treated in our hospital from May 2018 to May 2019 were selected and randomly divided into 2 groups, each containing 45. The control group received routine nursing, and the observation group performed standardized nursing intervention on the basis of the control group. The control group received conventional nursing, and the observation group performed standardized nursing intervention on the basis of the control group. After nursing, the two groups of patients were compared for their psychological state and nursing satisfaction. Results: After nursing, the HAMD and HAMA scores of the two groups were lower than before the nursing, and the observation group was lower than the control group, the difference was statistically significant(P<0.05). Conclusion: Standardized nursing intervention can alleviate the negative emotion of endoscopic examination of patients with gastric ulcer complicated with diabetes, which is conducive to the smooth progress of the examination.