bluuebunny/crossref_metadata_2025 huggingface dataset:
BIOMARKERS AND PROGNOSTIC SCORING IN CEREBRAL MALARIA
Authors: Pikatan Orlando , Ferlita Tirtana Ellen , Seraphine Kezia , Diarsvitri Wienta
Published: August 2022

Malaria remains a public health concern and remain the deadliest in infectious disease in the world. Cerebral malaria is a particularly severe complication of this disease and associated with high mortality. This literature review is made up from 19 literatures consisting of journals, and book. The literature review used data base www.pubmed.com, and www.scholar.google.com using “cerebral malaria and biomarker, predictor of cerebral malaria and treatment of severe malaria”. The languages for this journal are English and Indonesian. From the collection of literatures in this literature review, severe consists of cerebral malaria, blackwater fever, acute kidney injury, pulmonary edema, electrolyte disturbance, hematology disturbance, and obstetrics emergency resulting from malaria which is postpartum hemorrhage. Cerebral malaria increases the mortality of the patient, so they have to be diagnosed early and treated precisely. Patients with infection of plasmodium falciparum and GCS<11 must be suspected as cerebral malaria. Biomarker examination such as Soluble ICAM-1, Specific muscle’s protein, Angiopoetin-1 and 2, and Plasma microparticles is the most precise way to detect malarial emergency earlier Coma Acidosis Malaria score is also found to be useful in predicting the prognosis in cerebral malaria. Early diagnosis should be made as early as possible to reduce mortality from malaria and its emergencies.
Evaluation of grain size distribution of Wadi As Suqah, Northeast of Jeddah, Saudi Arabia
Authors:   Faculty of Earth Science, King Abdulaziz University, Jeddah, Saudi Arabia, Alotaibi Musaad A. , Alghamdi Mohammed A. M. ,   Faculty of Earth Science, King Abdulaziz University, Jeddah, Saudi Arabia
Published: August 2022

Wadi As Suqah, Makkah Governate, Western Saudi Arabia, has surficial sediments covering 300-422 square kilometers. The deposits may be used for any suitable construction material. Therefore, thirty-one samples of the Quaternary sands were collected from different locations along the study area to achieve this goal. The natural surficial grain sizes of Wadi As Suqah deposits in the Makkah region were assessed geotechnically, spatially, and mathematically. Rarely comprehensive exploration methodology, such as sieve analysis, 3D modeling, triangulation, and GIS, have been used to categorize the content percentage of grain sizes. Statistics and mathematics were also used to evaluate the correlations and assess the relationship between the fractions. This sophisticated approach is adapted for the first time on Wadi As Suqah, which concludes different results compared to previous studies. According to the unified soil classification system, gravel, sand, and fine had an average content of 85.1%, 11.7%, and 3.2%, respectively. Therefore, Wadi As Suqah, based on the fractions percentage, is categorized into four spatially sandy zones. At a coefficient of determination, R²=0.98, sand, and fine have a linear relationship. The major mathematical model is y=-1.02 x+100.5, in which y is the fine % content, and x is the sand % content. It can be merged with mineralogy for future studies to evaluate sediment from a geological engineering point of view.
A Study of Music Training for Cochlear Implant Users: Mismatch Negativity and Music Listening Attitude and Satisfaction Questionnaire
Authors: Shin Yerim , Yu Chaeyeon , Jo Sungmin , Kyong Jeong-Sug , Kim Jinsook
Published: August 2022

Purpose: The music rehabilitation program (MRP) promotes auditory, language, cognitive, and motor development of the brain. The significance of MRP was studied through mismatch negativity (MMN) and Music Listening Attitude and Satisfaction Questionnaire for hearing loss (MASQ_H). Methods: Fifteen adult cochlear implant (CI) users (34.5 years; standard deviation, ± 11.6) participated. MMN was tested before and after MRP training at the stimulus intensity level of 70 and 100 dB hearing loss (HL). In addition, MASQ_H was utilized. Results: For the pre- and post-tests of MMN, the average amplitudes of the waveforms were -2.48 ± 1.95 µV and -6.11 ± 4.21 µV and the areas were 208.16 ± 211.59 µV·ms and 527.87 ± 360.42 µV·ms with the significant difference when the stimulus level was presented at 70 dB HL. For MASQ_H, 90.9% of the participants responded that they felt satisfied with listening to music using CI or hearing aid. When asked about the musical factors that were improved in the music listening, the ‘pitch perception’ and ‘timbre perception’ were responded showing increased satisfaction rates. Conclusion: This study confirmed that MRP improved language processing by facilitating auditory processing, cognitive ability, and neural plasticity of the central auditory system through the increased amplitude and area of MMN after MRP application. Furthermore, providing a systematic music training such as MRP could change the music listening attitudes and satisfaction of the CI users’. The active implementation of music rehabilitation is strongly suggested.
Brotes de Sarcocystis spp. en aves exóticas mantenidas en cautiverio en el Zoológico de Cali: Serie de casos
Authors: Henao-Duque Ana María , Buitrago G Diana , Peña-Stadlin Juliana , Carvallo-Chaigneau Francisco
Published: August 2022

En un periodo de 19 meses se presentaron brotes en los cuales fallecieron 16 aves exóticas que pertenecían a la colección del Zoológico de Cali. La mayoría de los animales afectados fueron psitácidos australianos, de los cuales un gran porcentaje presentó muerte súbita. Las mortalidades se presentaron en recintos con diferentes características, localizados en zonas de exhibición y áreas internas del zoológico. Se realizó necropsia, histopatología e inmunohistoquímica en algunos animales que no presentaron estado avanzado de descomposición, donde se confirmó la presencia de una neumonía parasitaria con merozoitos de Sarcocystis spp. intraendoteliales. Algunos de los individuos que sobrevivieron recibieron una terapia combinada con antiparasitario, antibiótico y antifúngico. Se mencionan factores de riesgo y aspectos importantes en el manejo para prevenir la Sarcocistosis en estos animales mantenidos bajo cuidado humano, debido a que esta enfermedad presenta alta mortalidad en aves del viejo mundo, y a menudo cursa sin signos clínicos previos.
Developing Serious Video Games to Treat Attention Deficit Hyperactivity Disorder: Tutorial Guide
Authors: Sújar Aarón , Martín-Moratinos Marina , Rodrigo-Yanguas María , Bella-Fernández Marcos , González-Tardón Carlos , Delgado-Gómez David , Blasco-Fontecilla Hilario
Published: August 2022

Video game–based therapeutic interventions have demonstrated some effectiveness in decreasing the symptoms of attention deficit hyperactivity disorder (ADHD). Compared with more traditional strategies within the multimodal treatment of ADHD, video games have certain advantages such as being comfortable, flexible, and cost-efficient. However, establishing the most appropriate type(s) of video games that should be used for this treatment remains a matter of debate, including the commercial existing video games or serious video games that are specifically constructed to target specific disorders. This guide represents a starting point for developing serious video games aimed at treating ADHD. We summarize the key points that need to be addressed to generate an effective and motivating game-based treatment. Following recommendations from the literature to create game-based treatments, we describe the development stages of a serious video game for treating ADHD. Game design should consider the interests of future users; game mechanics should be based on cognitive exercises; and therapeutic mechanisms must include the control of difficulty, engagement, motivation, time constraints, and reinforcement. To elaborate upon this guide, we performed a narrative review focused on the use of video games for the treatment of ADHD, and were inspired by our own experience during the development of the game “The Secret Trail of Moon.”
A Machine Learning Approach for Continuous Mining of Nonidentifiable Smartphone Data to Create a Novel Digital Biomarker Detecting Generalized Anxiety Disorder: Prospective Cohort Study
Authors: Choudhary Soumya , Thomas Nikita , Alshamrani Sultan , Srinivasan Girish , Ellenberger Janine , Nawaz Usman , Cohen Roy
Published: August 2022

Background

Anxiety is one of the leading causes of mental health disability around the world. Currently, a majority of the population who experience anxiety go undiagnosed or untreated. New and innovative ways of diagnosing and monitoring anxiety have emerged using smartphone sensor–based monitoring as a metric for the management of anxiety. This is a novel study as it adds to the field of research through the use of nonidentifiable smartphone usage to help detect and monitor anxiety remotely and in a continuous and passive manner.

Objective

This study aims to evaluate the accuracy of a novel mental behavioral profiling metric derived from smartphone usage for the identification and tracking of generalized anxiety disorder (GAD).

Methods

Smartphone data and self-reported 7-item GAD anxiety assessments were collected from 229 participants using an Android operating system smartphone in an observational study over an average of 14 days (SD 29.8). A total of 34 features were mined to be constructed as a potential digital phenotyping marker from continuous smartphone usage data. We further analyzed the correlation of these digital behavioral markers against each item of the 7-item Generalized Anxiety Disorder Scale (GAD-7) and its influence on the predictions of machine learning algorithms.

Results

A total of 229 participants were recruited in this study who had completed the GAD-7 assessment and had at least one set of passive digital data collected within a 24-hour period. The mean GAD-7 score was 11.8 (SD 5.7). Regression modeling was tested against classification modeling and the highest prediction accuracy was achieved from a binary XGBoost classification model (precision of 73%-81%; recall of 68%-87%; F1-score of 71%-79%; accuracy of 76%; area under the curve of 80%). Nonparametric permutation testing with Pearson correlation results indicated that the proposed metric (Mental Health Similarity Score [MHSS]) had a colinear relationship between GAD-7 Items 1, 3 and 7.

Conclusions

The proposed MHSS metric demonstrates the feasibility of using passively collected nonintrusive smartphone data and machine learning–based data mining techniques to track an individuals’ daily anxiety levels with a 76% accuracy that directly relates to the GAD-7 scale.
The genetics monopolistic industry, as expected, is missing information two inches beyond their nose: in this case, transcripts (Preprint)
Authors: Bermúdez Juanjo
Published: August 2022

UNSTRUCTURED

De novo transcriptome assembly is one of the many fundamental pieces of new research in genomics. It is, for example, the preferred method for studying non-model organisms, since it is easier and cheaper than building a genome, and reference methods are not possible without an existing genome. The transcriptomes of these organisms can thus reveal novel proteins and their isoforms that are implicated in such unique biological phenomena. This technique is also useful in cancer research as it makes possible to detect potentially significant chimeric transcripts in cancer and normal somatic tissues.
Given that the genetics industry is organized in the form of a monopoly controlled by hidden lobbies who also control Academia, all the available software for de novo transcriptome assembly is being developed by academic researchers under the open-source paradigm. We report here, that as anyone could have very easily deduced from past experiences in other industries, this unethical form of organization in the industry is resulting in incompetence whose effects include missing a significant portion of the available information that could be obtained from some genomics studies. In this case, missing transcripts in transcriptome studies. We won't deep in on the consequences, but these could include overpricing, over costs, and failing to achieve the goals of some studies.
The Impact of Social Isolation, Loneliness, and Technology Use during the COVID-19 Pandemic on Health-Related Quality of Life: A Cross-Sectional Study (Preprint)
Authors: Balki Eric , Hayes Niall , Holland Carol
Published: August 2022

UNSTRUCTURED

This article has been written in research letter format, and thus did not require an abstract.
Development of a Smartphone Application for Dental Biofilm Control for Adolescents undergoing Fixed Orthodontic Treatment
Authors: Alves Ms. Cristiane Caram Borgas , Ortolani Dr. Cristina Lúcia Feijó
Published: August 2022

This work is aimed at the development of an electronic quiz-style game, available as an application for smartphones. The game was developed by a multidisciplinary team composed of dentistry and information technology professionals, who created a method of education compatible with the adolescent public, aiming to reduce oral problems arising from the prolonged use of fixed orthodontic appliances. As a result, a game was available free of charge at the smartphone application store, firstly tested by a team of orthodontics and periodontics clinicians, as well as computer professionals, who approved the quality and quantity of information provided to users as well as the usability of the application and clarity in the functions for the target audience.
A Survey of the Microbial Communities of Commercial Presliced, Packaged Deli-Style Ham Throughout Storage
Authors: Furbeck Rebecca A. , Bower Chad G. , Fernando Samodha C. , Sullivan Gary A.
Published: August 2022

The goal of this study was to evaluate the variation in spoilage microbiota associated with sliced, prepackaged deli-style ham from varying processing environments available in the retail market in the United States. Three different brands of presliced ham, water added were purchased at local markets and evaluated every 2 wk beginning 4 wk prior to the sell-by date until 4 wk beyond the sell-by date. Analysis of 16S ribosomal RNA genes using operational taxonomic units showed that Brand A had a different bacterial community structure compared with Brands B and C, according to unweighted (P=0.006) and weighted (P<0.001) UniFrac distance matrices. Brand A had a greater proportion of sequence reads mapping to Carnobacterium, Bacillus, and Prevotella, whereas B and C had greater proportions of Pseudomonas, Photobacterium, and Lactococcus. Brand A also had a lower salt concentration (P<0.007), greater moisture percentage and less fat percentage (P<0.012), and increased aerobic plate count (P=0.017). Differences in spoilage microbiota can in part be attributed to the factors involved with different processing locations, as shown by 3 different brands of ham, as well as slight differences in formulation including salt concentration and organic acid use.
Aprender, interpretar y actualizar
Authors: Rodriguez Suárez José Gregorio
Published: August 2022

Coherence between faith professed and life lived is fundamental for religious experiencecredibility. For Christianity, Jesus’ lessons are paradigmatic. So, what is learned isinterpreted and updated by his disciples in their vital contexts. The objective of this paperis to propose a way to overcome individualism and forms of spirituality withoutencountering God, based on Jesus’ teaching in Luke 10:25-37. Since this is a qualitativedocumentary study a bibliographical review is made to address the topic from a biblical-theological approach.  This paper shows partial results of PhD research in theology,concluding that love with words and actions is an ethical commitment to concrete serviceto others, as a manifestation of the authentic experience of God.
Performance Analysis of Wireless Sensor Network by Variation in Cluster Head Selection through mLEACH-CS Algorithm
Authors: Ghosh Arnab
Published: August 2022

Abstract: The energy depletion at the nodes due to large volume of data transmission and data reception for large scale Wireless Sensor Networks (WSN) is one of the important areas of concern. Unbalanced energy consumption due to data traffic overhead at the nodes near the base station (BS) results in early node death and reduction in network lifetime. To balance the load at the wireless nodes during clustering, a novel hybrid clustering and routing protocol has been proposed based on mLEACH (modified Low-Energy Adaptive Clustering Hierarchy) and Cuckoo Search (CS) algorithm. Initially, mLEACH protocol is utilized to solve a novel equation designed to select the cluster heads by rotation at every round of data transmission based on the maximum permissible cluster heads in the network. In the second phase, CS algorithm is implemented for uniform distribution of the cluster heads in the network for efficient multi-hop data routing in the network based on several weighted factors. The performance of the proposed algorithm is compared with other algorithms in literature in terms of energy consumption and network lifetime for different positions of the base station and varied number of cluster heads in the model application area. The proposed mLEACH-CS algorithm shows a significant improvement by 60% considering 300 nodes in the WSN architecture while it decreased to 40% for denser network architecture. Optimal choice of the number and position of the cluster heads in certain network architecture has proved beneficial for designing an energy efficient wireless network with improved network lifetime.
Performance Evaluation of Machine Learning Algorithms on Textual Datasets for Spam Email Classification
Authors: Mathur Shubham , Purohit Aakash
Published: August 2022

Abstract: Email is one of the most popular modes of communication we have today. Billions of emails are sent every day in our world but not every one of them is relevant or of importance. The irrelevant and unwanted emails are termed email spam. These spam emails are sent with many different targets that range from advertisement to data theft. Filtering these spam emails is very essential in order to keep the email space fluent in its functioning. Machine Learning algorithms are being extensively used in the classification of spam emails. This paper showcases the performance evaluation of some selected supervised Machine Learning algorithms namely Naive Bayes Classifier, Support Vector Machine, Random Forest, & XG-Boost for spam email classification on a combination of three different datasets. For feature extraction, both Bag of Words & TF-IDF models were used separately and performance with both of these approaches was also compared. The results showed that SVM performed better than all the other algorithms when trained with TF-IDF feature vectors. The performance metrics used were accuracy, precision, recall, and f1-score, along with the ROC curve.
Reseña: Miradas feministas a la obra de Vida Yovanovich: reflexiones sobre las mujeres en situaciones de encierro
Authors:   Universidad Autónoma de Baja California, Amao Ceniceros Melina
Published: August 2022

Miradas feministas a la obra de Vida Yovanovich: reflexiones sobre las mujeres en situaciones de encierro (2021) es el título del libro coordinado por las investigadoras Areli Veloz Contreras y Susana Gutiérrez-Portillo, adscritas al Instituto de Investigaciones Culturales (IIC-MUSEO) de la Universidad Autónoma de Baja California, institución encargada de esta publicación. El libro reúne las reflexiones de siete autorxs en torno a diversos temas relacionados con la obra de Vida Yovanovich, esto tras la exhibición de tres colecciones fotográficas que la autora montó en el MUSEO (espacio para exhibiciones artísticas del Instituto de Investigaciones Culturales de la UABC, en Mexicali) a inicios de 2020, y que se convirtió –sin poder anticiparlo– en la exposición más efímera que ha albergado dicho lugar a consecuencia del confinamiento por COVID-19. ¡La exposición abrió sus puertas solamente dos horas!
CONCEPTUAL ASPECTS OF THE PROBLEM OF POLITICAL REGULATION OF INTERNATIONAL RELATIONS IN THE FIELD OF INNOVATIVE TECHNOLOGIES
Authors:   Lomonosov Moscow State University, KHARITONOVA N.I. , LYZHIN D.N. ,   Russian Institute for Strategic Studies
Published: August 2022

The purpose of the article is to analyze the key scientific outlooks of the theory of international relations to comprehend the problem of innovative technologies and their impact on global processes. The authors consider that various scientific schools of the international relations theory think that the confrontation between states is moving from the military and economic sphere to a technological that built on innovation. This process irreversibly entails consequences, which are expressed in the increasing importance of technologies on the scale of national states and on an international scope. An analysis of conceptual approaches to the problem of the use and development of technologies showed that realistic concepts see them as one of the passive and non-systemic tools. States use innovations to ensure national security and increase competitiveness. Neorealists contend that the nature of the state and political forces are much more powerful than any technology. Followers of liberal schools are sure that the first place is to ensure the safety of using technology. Constructivists believe that to ensure the usefulness of a technological innovation, it must necessarily act in accordance with social norms. Supporters of the interdisciplinary school « Science, Technology and Society Studies » suggest the implementation of convergence between socio-political and technological structures. As a result, the authors draw conclusions that the developers of the “complex systems theory” have come closest to the implementation of an effective interdisciplinary synthesis and understanding of the problem of political regulation of modern technologies within the framework of global processes. The concept is based on synergetic ideas and sees the world order as a network structure with a multi-level system of interconnections, which at the same time has the ability to self-organize through the development of its units.
THE HIERARCHY OF PRIORITIES OF THE STATE YOUTH POLICY IN THE RUSSIAN FEDERATION: INNOVATIONS AND TRADITIONS
Authors:   Central Russian Institute of Management, Branch of RANEPA, MERKULOV P.A.
Published: August 2022

The purpose of the article is to analyze the priorities of youth policy of the Russian Federation. This policy assumes compliance with the principle of continuity and renewal. Much attention is given to a set of scientific and theoretical approaches and paradigms that take into account the factor of the presence of specific features of the State youth policy. The author draws attention to the need for theoretical and practical understanding of the effectiveness of youth policy. As a result, the author formulates the concrete proposals for the further development of the legal foundations of youth policy according with specific historical, sociopolitical and administrative conditions. The necessity of ideological, educational and organizational forms of work with the younger generation is given. Expert comments are made on the actions of the State with regard to youth in a new reality.
BUSINESS PROCESSES OF EDUCATIONAL SERVICES IN THE CONTEXT OF ECONOMIC MODERNIZATION AND NEW CHALLENGES
Authors:   Central Russian Institute of Management, Branch of RANEPA, GOLOVINA T.A. , OSTROUKHOVA D.K. ,   Central Russian Institute of Management, Branch of RANEPA
Published: August 2022

The purpose of the article is to reveal the concept of process approach to improve the quality of educational services of Higher Education System on the basis of highlighting the features of management of Higher Education institutions and the market of educational services in modern economic conditions. The article proves that currently the educational sphere is being formed very actively. It is stressed that the demands of society on the quality of education are increasing, learning technologies are constantly changing and being updated, innovations are emerging, and competitive rivalry between educational organizations is intensifying. The authors draw attention to the fact that it leads to the search for new effective ways to increase the competitiveness of educational organizations. The competitiveness of educational services is manifested in the orientation of educational organizations to the future state of the labor market. Much attention is given to business processes of educational services of higher educational institutions. The theoretical and methodological basis of the research are the works of Russian and foreign scientists devoted to the development of management of the higher education system, as well as the application of a process approach to management decisions aimed at improving the quality of educational services. As a result, the authors determine the role of the Higher Education System in the formation and development of human capital and modern challenges for Higher Education institutions. The expediency of applying a process approach to the management of educational services is reasoned. The key principles for the allocation of business processes of educational services and organizational and managerial measures to optimize them and improve the efficiency of functioning are proposed.
A TRANSFORMATION OF INNOVATION AND INVESTMENT POLICY OF AGRICULTURAL ENTREPRENEURSHIP
Authors:   Central Russian Institute of Management, Branch of RANEPA, POPOVA O.V. , ADAMENKO A.A. ,   Kuban State Agrarian University named after I.T. Trubilin
Published: August 2022

The purpose of the article is to analyze the factors that determine the need for transformation of agriculture, and the technical and technological opportunities that Agriculture 4.0 opens up to the subjects of agricultural entrepreneurship in terms of increasing production efficiency, ensuring fair distribution of added value along the commodity chain, and optimizing supplies. It is stressed that the transition to Agriculture 4.0 is associated with the problem of financial and physical access of agricultural producers to high-tech equipment, digital economy tools, and knowledge. The need to move from an extractive model of the innovation system to an inclusive one.is revealed. The principle of inclusion can be extrapolated to an economic agent of any level is clarified. The authors draw attention to the fact that the system of state support for agricultural producers in Russia does not meet the needs of accelerated technical and technological development of domestic agriculture. The role of large Russian agricultural structures of the holding type in the development of innovation and innovation transfer is presented. Some alternative schemes of innovation transfer that meet the signs of inclusion and increase the availability of innovative developments for financially vulnerable business entities are described. As a result, the authors develop a matrix of promising sources of investment financing for the enlarged stages of innovative product as well as some recommendations to improve state participation in the development of innovative infrastructure.
MODERN PRACTICES OF USING VIDEO HOSTING TO FORM A POSITIVE IMAGE OF EMPLOYEES OF INTERNAL AFFAIRS BODIES
Authors:   Orel Law Institute of the Ministry of the Interior of the Russian Federation named after V.V. Lukyanov, SALNIKOV E.V. , KIRYUKHINA Yu.V. ,   Orel Law Institute of the Ministry of the Interior of the Russian Federation named after V.V. Lukyanov
Published: August 2022

The purpose of the article is to analyze forming of a positive image of Internal Affairs bodies through the mass media. A comprehensive sociological analysis of available practices of using video hosting to form a positive image of officers of Internal Affairs bodies at the present stage is given. Much attention is given to the activities of divisions (departments, offices) to promote road traffic safety of the State Inspectorate For Traffic Security of the Ministry of Internal Affairs of Russia. The forms and methods of forming a positive image of traffic police officers in video hosting sites such as YouTube, Instagram* and TikTok are analyzed. It is also noted, that there are internal restrictive rules for the use of the studied media, which requires detail procedures for the use of the studied technologies to form a positive image of employees of Internal Affairs bodies. As a result, the authors draw conclusion that video hosting has an undoubted potential in forming a positive image of officers of Internal Affairs bodies.
The microbiome of the pelagic tunicate Dolioletta gegenbauri: a potential link between the grazing and microbiala
Authors: Pereira Tiago , Walters Tina , El-Shaffey Hisham , Bik Holly , Frischer Marc
Published: August 2022

Bloom-forming marine gelatinous zooplankton, including the pelagic
tunicate Dolioletta gegenbauri, occur circumglobally and have the
potential to significantly influence the structure of pelagic marine
food webs and biogeochemical cycling through interactions with microbial
communities. Using targeted metabarcoding (16S rRNA genes recovering
Bacteria/Archaea) and qPCR approaches associated with laboratory-based
feeding experiments, we characterized patterns in doliolid gut
microbiomes and microbial communities associated with doliolid fecal
pellets and the surrounding seawater. The characterization of starved
doliolids provides the first description of the doliolid gut microbiome.
At the highest taxonomic levels, doliolid-associated bacterial
communities are characteristic of marine bacterioplankton communities
around the globe and were dominated by representatives of six major
bacterial groups including Gammaproteobacteria, Alphaproteobacteria,
Cyanobacteria, Planctomycetes, Bacteroidia and, Phycisphaerae.
Comparison between sample types, however, revealed distinct patterns in
diversity and biomass supporting the hypothesis that through their
presence and trophic activity, doliolids influence the structure of
pelagic food webs and biogeochemical cycling in subtropical continental
shelf systems where doliolid blooms are common. Bacteria associated with
starved doliolids (representative of the resident doliolid gut
microbiome) possessed distinct communities, supporting the hypothesis
that doliolids possess a unique but low diversity, low biomass
microbiome optimized to support a detrital trophic mode. Among potential
core microbiome taxa, the genera Pseudoalteromomas and
Shimia were the most abundant, similar to patterns observed in
other marine invertebrates. Exploratory bioinformatic analyses of
predicted functional genes suggest that doliolids, via their
interactions with bacterial communities, may affect important
biogeochemical processes including nitrogen, sulfur, and organic matter
cycling.
Exact expressions of the fine-structure constant
Authors: Pellis Stergios
Published: August 2022

The purpose of many sciences is to find the most accurate
mathematical formula that can be found in the experimental value of
fine-structure constant. Attempts to find a mathematical basis for this
dimensionless constant have continued up to the present time. However,no
numerological explanation has ever been accepted by the physics
community. In this paper we will present the exact expressions for the
fine-structure constant. A simple and absolutely accurate expression for
the fine-structure constant in terms of the Archimedes constant. The
equivalent expressions for the fine-structure constant from the madelung
constant. Also a exact expression for the fine-structure constant in
terms of the golden angle,the relativity factor and the fifth power of
the golden mean. Also other expressions for the fine-structure constant.
Finally we will present the continued fractions for the fine-structure
constant.
Cultural Intelligence: Use Case of Haitian Refugee
Authors: Hussain Shafiq , Maker Paul
Published: August 2022

After providing the exact background to Haitian migration and its multifaceted vulnerability, this paper argues that diaspora geographies largely explain the location of Haitian refugees and asylum seekers in North America and the French Caribbean. Is. We then explore the relationship between the evolution of immigration coverage and the improvement of recent immigration routes in the direction of South America, where the spread of the multidimensional nature of this immigration paved the way for the legalization of Haitian immigration, particularly But in Brazil. The complementary immigrant characteristics of Ecuador, Peru, Brazil, and Chile have created an entirely new local immigrant machine centered on southeastern and southern Brazil. This emerging South-South migration route is part of a larger Haitian migration machine that connects Latin America with North America and the Caribbean.
Telangiectatic osteosarcoma in pelvis: a case report
Authors: Rothzerg Emel , Xu Jiake , Gibbons Max , Wood David
Published: August 2022

We report an uncommon case of pelvic telangiectatic osteosarcoma in a
young diabetic female who presented with a two-year history of a
painless limp. The clinical, radiological, and pathological features of
telangiectatic osteosarcoma of the pelvis and discuss how uncommon
symptoms can lead to diagnostic delay of the disease.
Electrogram-based AF ablation --finally, reproducibility!
Authors: Deisenhofer Isabel
Published: August 2022

Abstract: After several years with sobering experiences with
electrogram-based AF ablation approaches, Seitz et al present with the
VX1 software a reliable tool to map and ablate spatio-temporal
dispersion. The presented multicenter study in persistent AF patients
was conducted in 1 expert and 7 satellite centers with a total of 17
operators, using the VX1 software to detect and subsequently ablate
spatiotemporal dispersion. While the AF termination rate (88%) and the
freedom from AF in 12 months FU (82%) was very encouraging, the VX1
software, using AI enhanced electrogram adjudication, achieved very
similar results in all centers, regardless of the centre’s or the
operator’s experience. Thus, the biggest criticism of electrogram-based
ablation strategies, i.e. the lack of reproducibility in “non-expert”
centers, seems to be finally addressed.
Evaluation of variable speed drives to improve energy efficiency and reduce gas emissions: Case study
Authors: Sadek Mohamed , El-Maghraby Rehab , Fathy Mohamed
Published: August 2022

Variable speed drives are the most promising technique for reducing electric motors' energy consumption. This paper discusses energy savings by installing variable speed drives to control rotating equipment motors such as pumps, compressors, blowers, and fans in oil processing facilities. In addition to energy savings, variable speed drives will improve overall equipment efficiency, increase reliability, and reduce greenhouse gas (GHG) emissions. An energy audit was performed on a case study to investigate energy consumption for all electric motors. Technical and operational constraints for installing and operating variable speed drives were discussed. Installation requires adjustments in operation schedules and parameters to allow reducing energy consumption. The case study has illustrated how to calculate energy savings for pipelines, air coolers, air blowers for furnaces, pumps with variable flow rates, and reciprocating compressing systems. Variable speed drives were technically and economically accepted in air blowers, fans, and pumps. Energy consumption and GHG emission were reduced by 67%. The payback period for the whole project was less than one year. Meanwhile, it was not valid for reciprocating compressors as the payback period was 6.2 years.
The Use of Geographic Information in Audit Data Analytics for Evidence Gathering: A Design Science Approach
Authors: Huang Shi-Ming , Wang Tawei , Yen Ju-Chun , Lee Chi-Bei , Wang Yu-Chen , Yang Yi-Ting
Published: August 2022

Geographic information may be used in audit tasks, such as identifying high-risk cases involving suspicious entities usually located close to each other. However, the existing approach of text string analysis on addresses may only be able to match companies located in the same city or street. Following a design science approach, we propose using the geographic proximity of two locations to address how utilizing different levels of geographic information could improve the effectiveness and efficiency in auditing and other business tasks. As a proof of concept, we used Python and Google API to build Geographic Information in Audit Analytics (GIAA), a tool for automatically collecting, generating, and outputting spherical distance information indicating geographic proximity. We used a bid-rigging case to demonstrate GIAA and perform qualitative and quantitative evaluations. This study addresses how auditors and others can benefit from more advanced levels of geographic information, supporting better judgment and decision making.
Association and familial co-aggregation of childhood-onset type 1 diabetes with depression, anxiety, and stress-related disorders: a population-based cohort study
Authors: Liu Shengxin , Leone Marica , Ludvigsson Jonas F. , Lichtenstein Paul , D’Onofrio Brian , Svensson Ann-Marie , Gudbjörnsdottir Soffia , Bergen Sarah E. , Larsson Henrik , Kuja-Halkola Ralf , Butwicka Agnieszka
Published: August 2022

  

Objective

To estimate the association and familial co-aggregation of childhood-onset type 1 diabetes with depression, anxiety, and stress-related disorders.

Research design and methods

Population-based cohort study using data from Swedish nationwide registers. A total of ~3.5 million individuals born in Sweden 1973-2007 were linked to their biological parents, full- and half-siblings, and cousins. Cox models were used to estimate the association and familial co-aggregation of type 1 diabetes with depression, anxiety, and stress-related disorders. 

Results

Individuals diagnosed with childhood-onset type 1 diabetes (n=20,005) were found to be at greater risks of all outcomes: any psychiatric diagnosis (adjusted Hazard Ratio [aHR] [95% Confidence Intervals]: 1.66 [1.59-1.72]) or specific diagnoses of depression (1.85 [1.76-1.94]), anxiety (1.41[1.33-1.50]), stress-related disorders (1.75 [1.62-1.89]), as well as using antidepressants or anxiolytics (1.30 [1.26-1.34]), compared to individuals without type 1 diabetes. Overall, relatives of individuals with type 1 diabetes were at elevated risks of developing these outcomes, with the highest risks seen in parents (aHRs: 1.18-1.25), followed by full-siblings (aHRs: 1.05-1.20), and the magnitudes of risk estimates appear proportional to familial relatedness.

Conclusion

These results support existing evidence that children and adolescents with type 1 diabetes are at greater risks of developing depression, anxiety, and stress-related disorders and indicate that shared familial factors might contribute to these elevated risks. Our findings highlight the need for psychological consulting for children and their families in diabetes care. Quantitative and molecular genetic studies are warranted to further understand the etiology of these psychiatric disorders in type 1 diabetes. 
Realistic Mathematic Education-Based Student Worksheet to Improve Students' Mathematical Reasoning on Circle Material
Authors: Erita Selvia , Utami Ecci Siski Dinda , Ningsih Febria
Published: August 2022

Mathematical reasoning is a critical feature emphasized in the objective of mathematics education since it may be utilized to solve mathematical problems and other difficulties. This study aims to provide student worksheets based on Realistic Mathematics Education (RME) on circle material that are valid, practical, and useful in increasing students' mathematical reasoning abilities. This research used a 4-D development model. Validation sheets, practicality questionnaires, and test questions were employed as research tools. As a result of this research, the RME-based student worksheet on circle material is declared valid in content/material with an average of 4.05 and constructively valid with an average of 3.85. The practical findings show a value of 80.77% in the practical category. The effectiveness test revealed an N-Gain value of 0.57 with a fairly effective category. It may be concluded that the RME-based student worksheet developed is feasible, practical, and effective. As a result, the RME-based student worksheet can be used in learning to improve students' mathematical thinking abilities.
Pengaruh Authentic Learning Berbasis Lingkungan terhadap Kemampuan Berpikir Kritis dan Pemecahan Masalah IPA
Authors: Mahrus Mahrus , Anggraeni Mira Natika , Silmi Idam Matus
Published: August 2022

Penelitian ini bertujuan untuk menguji pengaruh penggunaan aunthentic learning berbasis lingkungan pada keterampilan berpikir kritis dan memecahkan masalah sains. Penelitian ini menggunakan Desain Kelompok Kontrol Pretest-Posttest. Subjek penelitian yang digunakan sebanyak 48 siswa yang kemudian dibagi kedalam 2 kelompok eksperimen dan kontrol, dipilih menggunakan teknik sampling jenuh. Kelompok eksperimen terdiri dari 24 siswa yang diberi perlakuan menggunakan pembelajaran aunthentic berbasis lingkungan sedangkan kelompok kontrol terdiri dari 24 siswa menggunakan pembelajaran konvensional. Teknik pengumpulan data yang digunakan adalah guestionnaires dan tes. Teknik analisis data menggunakan analisis parametrik one way ANOVA. Hasil penelitian menunjukkan bahwa ada perbedaan nilai rata-rata antara kelompok eksperimen dan kelompok kontrol, di mana nilai rata-rata kelompok eksperimen lebih tinggi daripada kelompok kontrol. Berdasarkan hasil ini dapat disimpulkan bahwa metode aunthentic learning berbasis lingkungan berpengaruh terhadap peningkatan kemampuan berpikir kritis dan menyelesaikan masalah sains siswa kelas V di MI Manbaul Huda Purwodadi Temanggung.
Content of CD4+ cells expressing CD39/CD73 ectonucleotidases in children with inflammatory bowel diseases
Authors: Radygina TV , Petrichuk SV , Kuptsova DG , Potapov AS , Illarionov AS , Anushenko AO , Kurbatova OV , Semikina EL
Published: August 2022

The regulation of TNF inhibitor therapy-associated immune responses in inflammatory bowel diseases (IBD) in children remains an urgent problem. The study aimed at analyzing the expression of CD39/CD73 endonucleotidases by different subsets of peripheral blood T cells in children with IBD including Crohn's disease (n = 34) and ulcerative colitis (n = 33) having received TNF inhibitors in comparison with conditionally healthy children (n = 45). Lymphocyte subsets including regulatory T cells (Treg, CD4+CD127lowCD25high), activated T cells (Tact, CD4+CD25+CD127high) and Th17 cells (CD4+CD161+CD3+) were studied by flow cytometry. The results are presented as medians (Me) and quartiles (Q25–Q75). In children with IBD the highest and the lowest relative counts of CD39+ cells were found in Treg and Tact subsets — 31% (15–38) and 4% (1–7), respectively. The highest relative counts of CD73+ cells were found in Tact — 13% (8–21). The CD39 and CD73 expression ratio in patients with IBD, and in the control group as well, depended on particular subset. CD39 expression in Treg, Tact and Th17 of patients with IBD was not age-dependent. Patients with acute Crohn's disease revealed decreased expression of CD39 in Treg compared with the control group (12% (9–23) vs 35% (28–39), respectively; р = 10–6). Patients with Crohn's disease in remission revealed increased expression of CD39 in Treg compared with the acute of the disease (31% (27–40) vs 12% (9–23); р = 9.4 × 10–5). Patients with Crohn's disease in remission revealed no significant differences with the control group apart from reduced expression of CD73 by Treg in Crohn's disease. The results indicate significant association of CD39 and CD73 expression levels in particular subsets of CD4+ cells with the phase of the disease (acute vs remission) and, accordingly, with the anti-TNF regimen efficacy.
Soderzhanie CD4+-kletok s ekspressiej ektonukleotidaz CD39/CD73 u detej s vospalitel'nymi zabolevaniyami kishechnika
Authors: Радыгина Т. В. , Петричук С. В. , Купцова Д. Г. , Потапов А. С. , Илларионов А. С. , Анушенко А. О. , Курбатова О. В. , Семикина Е. Л.
Published: August 2022

Izuchenie regulyacii immunnogo otveta na fone terapii blokatorami TNF pri vospalitel'nyh zabolevaniyah kishechnika (VZK) u detej ostaetsya aktual'noj problemoj. Cel'yu issledovaniya bylo izuchit' ekspressiyu CD39/CD73 v subpopulyaciyah limfocitov (regulyatornyh T-kletok (Treg) — CD4+CD127lowCD25high; aktivirovannyh T-kletok (Tact) — CD4+CD25+CD127high; Th17-limfocitov — CD4+CD161+CD3+) perifericheskoj krovi u detej s VZK (s bolezn'yu Krona (BK), n = 34; s yazvennym kolitom — n = 33), prinimavshih blokatory TNF, i u 45 uslovno zdorovyh detej. Rezul'taty predstavleny v vide mediany (Me) i kvartilej (Q25–Q75). S pomoshch'yu mnogocvetnoj citometrii pokazano, chto u detej s VZK naibol'shee kolichestvo CD39+ vyyavleno v populyacii Treg — 31% (15–38), naimen'shee — v Tact 4% (1–7), a naibol'shee kolichestvo CD73+ — v Tact 13% (8–21). Sootnoshenie ekspressii CD39 i CD73 u pacientov s VZK, tak zhe kak i v gruppe sravneniya, zaviselo ot populyacii kletok. Ekspressiya CD39 v Treg, Tact i Th17 u pacientov s VZK ne zavisela ot vozrasta rebenka. V gruppe detej s BK v obostrenii otnositel'no gruppy sravneniya polucheno snizhenie ekspressii CD39 v Treg (12% (9–23) protiv 35% (28–39), r = 0,000001). U detej v remissii BK ekspressiya CD39 v Treg dostoverno vyshe, chem pri obostrenii (31% (27–40) protiv 12% (9–23); r = 0,000094)). Mezhdu gruppoj pacientov v remissii i gruppoj sravneniya dostovernyh razlichij vyyavleno ne bylo, za isklyucheniem snizheniya ekspressii CD73 v Treg pri BK. Poluchennye rezul'taty pokazyvayut, chto ekspressiya CD39 i CD73 v populyaciyah CD4+-limfocitov v znachitel'noj stepeni svyazana s techeniem zabolevaniya, s obostreniem ili remissiej, i, sootvetstvenno, s effektivnost'yu provodimoj anti-TNF-terapii.
Origen y actualidad del Taekwondo (WT) femenino en la Argentina: una perspectiva de género
Authors: Angiolillo Luciana
Published: August 2022

Los registros de la historia femenina en Taekwondo son limitados debido a los convencionalismos sociales, culturales e ideológicos sobre la participación de la mujer en los deportes. Este trabajo propone una contribución inicial al origen, desarrollo y actualidad femenina del “Taekwondo Olímpico”, así denominado popularmente. El objetivo principal de la investigación es identificar y exponer la participación femenina en el Taekwondo WT argentino, desde su origen hasta nuestros días, a partir de un ciclo de entrevistas a mujeres argentinas destacadas en la disciplina. También, este artículo identifica las contribuciones de las mujeres en los desafíos internacionales del deporte en categorías adultas. Además, sintetiza y condensa los momentos históricos que han determinado la universalidad de la subordinación femenina, descubriendo y reconociendo sus formas androcéntricas, para contribuir a la deconstrucción de esta ideología imperante que se ha sustentado durante siglos de historia. Así, en el Taekwondo como en todas las actividades humanas, la lucha y el debate por una equidad de género aún es una tarea inacabada.