bluuebunny/crossref_metadata_2025 huggingface dataset:
Interferon-gamma release assay has poor diagnostic accuracy in differentiating intestinal tuberculosis from Crohn’s disease in tuberculosis endemic areas
Authors: Sachdeva Karan , Kumar Peeyush , Kante Bhaskar , Vuyyuru Sudheer K. , Mohta Srikant , Ranjan Mukesh K. , Singh Mukesh K. , Verma Mahak , Makharia Govind , Kedia Saurabh , Ahuja Vineet
Published: June 2022

Background/Aims: Intestinal tuberculosis (ITB) and Crohn’s disease (CD) frequently present with a diagnostic dilemma because of similar presentation. Interferon-gamma release assay (IGRA) has been used in differentiating ITB from CD, but with sparse reports on its diagnostic accuracy in tuberculosis endemic regions and this study evaluated the same.Methods: Patients with definitive diagnosis of ITB (n=59) or CD (n=49) who underwent IGRA testing (n=307) were retrospectively included at All India Institute of Medical Sciences, New Delhi (July 2014 to September 2021). CD or ITB was diagnosed as per standard criteria. IGRA was considered positive at >0.35 IU/mL.Relevant data was collected and IGRA results were compared between ITB and CD to determine its accuracy.Results: Among 59 ITB patients (mean age, 32.6±13.1 years; median disease duration, 1 year; male, 59.3%), 24 were positive and 35 tested negative for IGRA. Among 49 CD patients (mean age, 37.8±14.0; median disease duration, 4 years; male, 61.2%), 12 were positive and 37 tested negative for IGRA. Hence, for diagnosing ITB, IGRA showed a sensitivity, specificity, positive and negative predictive values of 40.68%, 75.51%, 66.67%, and 51.39%, respectively. The area under the curve of IGRA for ITB diagnosis was 0.66 (95% confidence interval, 0.55–0.75). In a subset (n=64), tuberculin skin test (TST) showed sensitivity, specificity, positive and negative predictive values of 64.7%, 73.3%, 73.3%, and 64.71%, respectively. IGRA and TST were concordant in 38 (59.4%) patients with κ=0.17.Conclusions: In a tuberculosis endemic region, IGRA had poor diagnostic accuracy for differentiating ITB from CD, suggesting a limited value of IGRA in this setting.
Determinanty rozwoju rynku pożyczek pozabankowych w Polsce – perspektywa ekonomiczna, regulacyjna, technologiczna i socjologiczna
Authors: Jakubowska-Branicka Iwona , Walczak Bartłomiej , Waliszewski Krzysztof
Published: June 2022

Opierając się na badaniach wtórnych i pierwotnych dokonano charakterystyki determinant rozwoju rynku pożyczek pozabankowych w Polsce z perspektywy ekonomicznej, regulacyjnej, technologicznej i socjologicznej. Determinanty te wpływają na zmianę modelu instytucji pożyczkowej z uwzględnieniem średniej kwoty pożyczki, kanału dystrybucji i profilu finalnego nabywcy. Od 2015 r. sektor pożyczkowy w Polsce, początkowo zupełnie nieuregulowany systemem prawnym, jest obecnie prawnie uregulowany przepisami w znacznym stopniu ograniczającymi początkowo stosowane lichwiarskie praktyki, a także jest poddany nadzorowi ze strony Komisji Nadzoru Finansowego, która od 2017 r. prowadzi publiczny rejestr instytucji pożyczkowych. Klienci zaciągający pożyczki pozabankowe są wykluczeni kaskadowo, a ich zadłużenie pożyczkowe wynika najczęściej z przymusu ekonomicznego. Zapowiedziane zaostrzenie przepisów antylichwiarskich może doprowadzić do całkowitego zaniku tego sektora, przez to obecni jego klienci będą zmuszeni skorzystać z oferty pożyczek w szarej strefie (podziemiu pożyczkowym), gdzie nie obowiązują żadne przepisy prawne i reguły.
WPŁYW WYDATKÓW BUDŻETOWYCH NA ZMIANY STRUKTURALNE I DOCHODY W ROLNICTWIE W WARUNKACH FUNKCJONOWANIA W POLSCE INSTRUMENTÓW WPR
Authors: Czyżewski Andrzej , Kata Ryszard , Matuszczak Anna
Published: June 2022

Wydatki budżetowe na rolnictwo stanowią narzędzie realizacji celów polityki rolnej. Na wydatki budżetu rolnego Polski składają się środki krajowe oraz środki europejskie. W kontekście dyskusji na temat modyfikacji wspólnej polityki rolnej na lata 2021–2027 dokonano oceny dotychczasowych efektów alokacyjnych, redystrybucyjnych i stabilizacyjnych wydatków budżetowych na rolnictwo, od momentu objęcia tego sektora w Polsce instrumentami WPR. Założono, że znaczący wzrost wydatków budżetowych na rolnictwo od 2004 r. wpłynął na alokację czynników wytwórczych w tym sektorze oraz na dochody rolników. Celem badań było ustalenie kierunku oddziaływania wydatków budżetowych na koncentrację czynników wytwórczych w rolnictwie oraz poziom, stabilność i zróżnicowanie dochodów rolników. Wykazano, że wydatki budżetowe są dodatnio powiązane z procesem koncentracji zasobów ziemi oraz koncentracją nakładów kapitałowych w rolnictwie. Redystrybucyjne efekty wzrostu wydatków budżetowych to realny wzrost dochodów rolniczych i zmniejszenie luki dochodowej pomiędzy rolnikami a innymi grupami społeczno-zawodowymi. Potwierdzono stabilizacyjne efekty wydatków budżetowych, bowiem dochody z rodzinnego gospodarstwa rolnego zawierające subsydia wykazują znacznie mniejszą zmienność niż dochody uzyskane jedynie na rynku. Transfery budżetowe w formie subsydiów wspierających dochody rolników nie są w stanie odwrócić procesu postępującej polaryzacji dochodów gospodarstw rolniczych, ale łagodzą narastające nierówności.
One Third of the Century of Postsocialist Systemic Transformation
Authors: Kołodko Grzegorz W.
Published: June 2022

Teoria zmian ustrojowych nie udzieliła jednoznacznej odpowiedzi co do ram czasowych, w których przebiega posocjalistyczna transformacja ustrojowa; celowe jest zatem wskazanie kryteriów jej zapoczątkowania oraz zakończenia. Wymaga to analizy porównawczej w odniesieniu
do sfery realnej oraz sfery regulacji reformowanej gospodarki państwowego socjalizmu oraz wyłaniającej się z niego posocjalistycznej gospodarki rynkowej. Taka analiza musi być dokonana w odniesieniu do modelu neoliberalnego gospodarki opierającego się na Konsensusie
Waszyngtońskim, co było w Polsce podstawą tzw. szokowej terapii, oraz do społecznej gospodarki rynkowej, która była celem późniejszej Strategii dla Polski. Zarówno literatura przedmiotu, jak i studia statystyczne wyraźnie pokazują, że polityka liberalizacji i stabilizacji
z początku lat 90. była zbyt radykalna i zaszkodziła realnej sferze gospodarki, nie tworząc zarazem odpowiednich jakościowych przesłanek do rozwoju gospodarczego w następnych latach. Trwałe podstawy dynamicznego rozwoju stworzyła dopiero polityka reform i budowy instytucji prowadzona w latach realizacji Strategii dla Polski. Analiza minionej jednej trzeciej wieku głębokich przemian ustrojowych wskazuje na niejednolitość poszczególnych etapów rozwoju, co było skutkiem odmiennego formułowania celów rozwojowych i stosowania zróżnicowanych instrumentów polityki zmian instytucjonalnych i wzrostu gospodarczego. Z doświadczeń wysiłku transformacyjnego w tym długim okresie wynikają na przyszłość liczne wnioski pod adresem polityki potrójnie – ekonomicznie, społecznie i ekologicznie – zrównoważonego rozwoju, która musi brać pod uwagę determinanty społeczne i kulturowe.
Arguments for the Use of Growth Accounting in the Research on Regional Specialization
Authors: Kotlewski Dariusz
Published: June 2022

Artykuł podejmuje problem sposobu badania specjalizacji regionalnych (w tym inteligentnych specjalizacji), które zwiększają konkurencyjność oraz zapewniają przyśpieszenie rozwoju gospodarczego regionów. Autor uważa, że klasyczna teoria handlu ma tutaj ograniczone zastosowanie, natomiast pomocna może być nowa geografia ekonomiczna Krugmana. Autor przywołuje teorię Ricciego, łączącą te teorie, która kładzie nacisk na wzrost produktywności jako czynnik pomagający w wyjściu z niedorozwoju. Autor przedstawia rachunek produktywności KLEMS i podaje wyniki badań pokazujące, że ta metoda badania specjalizacji regionalnych ma przewagę nad innymi metodami.
The Semantic Content of the Values of Police Officers with Different Levels of Personal and Professional Fulfilment
Authors: onomarenko Yana Ponomarenko
Published: June 2022

The article presents a brief overview of theoretical developments in the field of values of police officers in domestic and foreign studies. It is stated that in the field of psychology, personal values are often the object of research and usually have a variety of interpretations. Attention is focused on the fact that in the context of this work, values are understood as deeply rooted motives that form the semantic content of attitudes and standards of personal behaviour, which in the professional sense improves the specialist’s awareness of not only the importance of her/his professional activity but also the significance of her/his own contribution to its qualitative performance. The values of police officers play an important role in their effective psychological functioning and guide their further development. The aim of the article was to establish the semantic content of values and spheres of life in police officers with different levels of personal and professional fulfilment (PPF). To form the groups in the empirical study, the cluster analysis was applied by the k-means using data obtained with the help of the questionnaire of personal fulfilment (PF) by O. Shtepa and the questionnaire of professional self-fulfilment (PS) by O. Kokun. The data obtained in the study of PPF allowed dividing the total selection of police officers, which included 203 people, into three groups: the first group (low level of PPF) included 68 persons, the second group (high level of PPF) – 92 respondents, the third group (medium level of PPF) – 42 surveyed. It has been empirically established, that police officers who have a low level of PPF stand out by their striving for financial stability, and they need to have time for hobbies, which allows them to replenish resources. Police officers who obtain a high level of PPF take care of their image, they can creatively solve complex problems, they care about social development issues and strive for success in the profession. Professional and family life are important for police officers with a low level of PPF. Spheres of professional, family, and social life, the combination of which is optimal for qualified law enforcement officers, have become dominant within police officers with the high level of PPF. Police officers with the high level of PPF prefer to fully realize themselves in the profession, they want to be valued within it, to have a positive image, while devoting time to family and study
Internet Addiction as One of the Main Types of Addiction in Modern High-School Students
Authors: Makariuk Zhanna
Published: June 2022

Nowadays, the Internet is a tool that is becoming imperative in everyday life. The pandemic in the modern world has exacerbated the problem of Internet addiction, creating the conditions for humanity to stay longer online. Since the majority of users are adolescents and young people, they form the main risk group, which is prone to Internet addiction. The purpose of the study was to explore the features of Internet addiction in high school students in modern Ukrainian society. The study included a comprehensive approach, which provided a combination of the following methods: theoretical (analysis, synthesis, generalisation, and systematisation of conceptual provisions on the problem under study); empirical (testing, in particular the method: “Chen Internet Addiction Scale” (CIAS adapted by L. Maligin, K. Feklisov); method of statistical processing. The paper reveals the problem of Internet addiction in high school students in modern conditions, the problems that arise in connection with such dependence, and considers the symptoms of Internet addiction and the reasons for its development. The study discusses the results of the investigation of Internet addiction in high school students, and also reveals differences in components of Internet addiction in adolescents with different levels of addiction. The findings show that most high-school students are prone to Internet addiction, which necessitates timely primary prevention of Internet addiction, starting in adolescence. In addition, a comparative analysis found that subjects with persistent Internet-dependent behaviour were more likely to have compulsive symptoms, withdrawal symptoms, tolerance symptoms, intrapersonal and health problems, time management problems, and stress
Educational Work in General Secondary Education Institutions: Modern Aspects
Authors: Mykhed Inna
Published: June 2022

The relevance of the research topic is due to the fact that the education system does not meet the needs of modern personality. To bring up and develop the necessary skills that will help the child to adapt to the conditions in society, it is necessary to adjust the systemic approach of educational institutions. After all, today it is necessary to have a considerable resource to effectively cope with life’s difficulties. The foundation of this is laid during the school period. Therefore, the main task of educational institutions is to form a personality that is full of vitality and resilience in the modern world, strong spirit, initiative, morality, determination and great leadership potential, competitiveness, life skills, creativity and self-realisation. Therefore, based on this, the purpose of this article is to analyse the readiness of both teachers and students to innovate in the educational process at school. The object is the educational process itself as a major factor in innovative changes. The subject of research is the features of educational work in educational institutions. To effectively achieve the goal, several tasks were set, in particular, to analyse theoretical research on the topic of the article; determine the list of methods that will form the basis of empirical research; to conduct research and formulate conclusions, recommendations based on their results. As for the methods used during the writing – a range of theoretical (analysis, synthesis, generalisation, justification) and practical (content analysis, observation, conversation, testing, questionnaires) methods. The performed study provides an opportunity to generate the following results: today the teaching staff and students of secondary schools are not psychologically ready to introduce innovative mechanisms into the established educational process. In addition, the material and technical base of schools also does not correspond to the progressive strategies of modern personality development. Therefore, for the administration of educational institutions, there is an urgent need to work towards modern educational changes for the effective education of the younger generation. The results of the study will be useful for teachers, principals, social educators, psychologists, students of pedagogical universities and more
The Diagnostics of the Development of Cooperative Skills of Future Primary School Teachers
Authors: Horvat Marianna , Kuzma-Kachur Mariia
Published: June 2022

The study has focused on the importance of implementing the main provisions of the NUS concept, which produce the educational process based on subject-subject interaction. It has been emphasised that the new paradigm of future primary school teacher training generates new ideas into educational practice based on dialogue, cooperation, co-creation, collective action, respect for each individual, the need to understand another position, etc., which are formed in the process of cooperative learning. Therefore, pedagogical higher educational establishments should provide conditions in the system of professional training for the development of students’ cooperative skills. The purpose of the study is to describe the diagnosis of the readiness of future teachers to improve cooperative skills with the help of interactive technologies in the educational process of primary school. The study applied the following methods: “Value orientations” (M. Rokych) and “Map of research of the motivational component of readiness”, questionnaires, “Map of research of the communicative component of readiness”. The authors have described the results of the study on motivational and value, cognitive, activity and communicative components of the readiness of future primary school teachers to form cooperative skills in younger students. It has been found that applicants for higher education in the second year of study are dominated by the average level of development of cooperative skills on all criteria, which aims to further improve the educational process in the lens of research. It has been emphasised that interactive technologies involve the organisation of cooperative learning, when individual tasks grow into a group, where each member of the group contributes to joint activities. The recommendations have been developed that are useful to take into account when organising the process of cooperative learning in classes at higher educational establishments
The Use of Scientific Organisation Methods of Labour in the System of Work of Design and Technology Teachers
Authors: Berbets Tetiana , Berbets Vitalii
Published: June 2022

The relevance of the study is conditioned by the need to implement solutions that contribute to the development of schools and institutions, acting in changed organisational conditions, working using methods of scientific organisation of labour in the system of work of Design and Technology teachers. Solutions that allow organising the learning process using such methods contribute to the implementation of didactic and educational tasks defined by schools and educational institutions. The purpose of these measures is to ensure the implementation of the main curriculum, taking into account the limitations arising from the specifics of the activities being carried out. In the current circumstances, the key issue is reasonableness and consideration of the current state of the organisation of subject training, considering the correct approach to the material provided to students, instructions, and tasks. The purpose of the study is to consider effective methods of scientific organisation of labour in the system of work of Design and Technology teachers. The theoretical and methodological basis of the study consists of the following methods: correlation, empirical, and component analysis. It is important to constantly develop the skills in this area, use the wide variety of modern technologies dedicated to this activity, overcoming the technological barrier. Organisation and planning are one of the main conditions for the effectiveness of any conscious and purposeful activity of a teacher, especially long-term ones, throughout the school year. The system of work of a Design and Technology teacher distinguishes the tasks assigned to such a teacher in an educational institution in the context of the performed functions. The teacher should certainly take into account the tasks that follow from the analysis of the provisions of the educational process that regulate the sphere of activity of a school teacher. The practical significance lies in the productive use of methods of scientific organisation of labour in the system of work of Design and Technology teachers
The Use of the Methodology for Determining the Levels of Organisational and Structural System in the Study of the Efficiency of Foreign Students' Social and Pedagogical Support (on the Example of the US HEIs)
Authors: Slutskiy Yaroslav
Published: June 2022

The article examines the problem of foreign students’ social pedagogical support in the context of the effectiveness of preparatory systems in the educational institutions, which determines the relevance of the scientific research – the definition of an effective methodology for analysing the level of structure of the adaptation system of foreign students’ training in the educational institution. Due to the relevance of the research, the purpose of the article is to investigate the system of social and pedagogical support for foreign students in higher education institutions of the United States of America using the method of determining the levels of the organisational and structural system of elements of the acculturation triad. That’s why a method of determining the levels of the organisational and structural system has been proposed, which provides the distribution of the analysed branching program into four levels. In addition, the research required the use of a systematic method (to determine the integrity and structure of the process of socio-pedagogical support), the method of classification (which allowed to distribute the preparatory programs by the elements of the acculturation triad) and the abstraction (aimed at a visual representation of the levels of organisational and structural system). It is emphasised that the support consists of elements of the acculturation triad, such as: educational and cultural, psychological, and linguistic. Each of these elements should be presented as a programme branch, coordinated by the preparatory centres. It was found that the number of levels at which the programmes of the analysed unit or educational institution are presented is directly related to the effectiveness of the process of foreign students’ training. As an example of the analysis with the use of this method, the higher educational institutions representing the United States of America were selected (since this country (according to UNESCO) has the largest number of foreign students). As a result, the following HEIs were selected: University of Texas at Austin, Florida Institute of Technology, Ohio State University, and Yale University. The performed analysis allowed saying that the most branched organisational and structural system is presented (among the selected HEI) in the linguistic orientation of Yale University and is characterised by four levels of program branching. The lowest level (only highest) of branching was found in the educational and cultural direction of the Florida Institute of Technology. The presented methodology can be used in theoretical researches and practical analysis of the effectiveness of adaptation centres for foreign students
Ways to Reform the Banking System of Ukraine to Ensure the Financial Stability of Economic Entities
Authors: Roshilo Violetta
Published: June 2022

The article analyses the main directions of reforming the banking system of Ukraine. The relevance of the study is conditioned upon the need to improve the stability of the country's financial system. The reason for the decline in the economic situation is the political situation in Ukraine. The purpose of the study is to clarify ways to ensure the financial stability of enterprises for long-term and sustainable economic development. In the course of the research philosophical and general scientific methods were used , in particular historical-logical, economic-statistical, factorial methods, including theoretical and comparative analysis. The author assesses the consequences of the application of some methods at certain stages of development of the banking system, identifies the main priority areas of its development; the approaches to definition of essence and features of development of financial resources of the enterprise are analysed; the relationship between the financial stability of the state structure and the financial stability of the enterprise is identified; measures to ensure the financial stability of the enterprise, and opportunities to improve the system of ensuring and forecasting financial stability. The rapid development of information technology, which allows Ukrainian banks to expand the range of services; increasing the financial literacy of clients and implementing programs aimed at maintaining the stable condition of domestic financial institutions. A detailed analysis of management elements, functions and principles of development of financial resources of the enterprise is given. The analysis allows stating that the financial resources of the enterprise should be defined as a set of own funds of the organization and external financing, which can be used to form fixed and current assets needed to conduct business and support expanded production. Having a high transformative capacity, the financial resources of the enterprise are the main component of financial potential, a factor of economic and social development. The article identifies the factors influencing the financial stability of the enterprise, and areas for improving public financial control in the context of financial security of Ukraine. The urgency of the researched problem is determined by the need to develop a strategy of financial security of Ukraine in view of the problems that complicate it. Analysis of the financial stability of the enterprise is the most important step in assessing its performance and financial and economic well-being
Analytical Review of Small Farms of Ukraine Registered as a Natural Person-Entrepreneur of the 4th Group: Influence of Specific Features of Accounting and Auditing on the Dynamics of Their Development and Decline as of 2021
Authors: Jensen Ida
Published: June 2022

The urgency of the research is that the study of small farms will form a system of agricultural entrepreneurship, which will be the main direction in the development of rural areas and will bring the local economy out of a certain depressed status. The purpose of the study is to examine the theoretical and practical aspects that will help to learn more about the definition of “small farms registered as natural persons-entrepreneurs of the 4th group”, determining the legal status of these small farms and analysis of practical implementation of this sector in Ukraine. The main methodological approaches that allow identifying the theoretical and practical content of the study topic are the theoretical approach, monographic method, formal-legal method, method of comparative analysis, functional methodological approach, method of economic analysis, deduction method, induction method, and hypothetical and systemic methods. As a result of the work on the study of small farms of Ukraine registered as natural persons-entrepreneurs of the 4th group, the mechanism of implementation of the farm in general was studied, the specific features of the study sector were analysed and a comparative analysis of the implementation of the farm sector in Ukraine and foreign countries was conducted. The identified theoretical and practical aspects of the study will help in conducting an analysis to determine the impact of features that arise during accounting and auditing on the development and decline of the small farm sector of Ukraine, which are directly registered as a natural person-entrepreneur of the 4th group
Analysis of risk factors related to early post-traumatic seizures and post-traumatic epilepsy
Authors: Lee Sang-Hoon , Koh Eun Jeong , Choi Ha-Young , Park Jung-Soo , Lee Jong-Myong , Jang Hyoung-Gyu
Published: June 2022

Objective: We investigated factors associated with early post-traumatic seizures (EPTSs) and post-traumatic epilepsy (PTE) to determine factors associated with PTE in comparison with previous reports. Methods: We enrolled 78 patients with acute head trauma from January 2008 to December 2011 (range of follow-up duration, 5–12.9 years). We conducted a comparative analysis of various factors in both groups.Results: Nine of the 78 patients experienced EPTSs during admission, and 18 patients developed PTE. All nine patients with EPTSs progressed to PTE. Treatment type, academic background, marital status, hemoglobin at hospital day 1 (HD#1), Glasgow coma scale (GCS) at admission, GCS at discharge, and the modified Rankin score (mRS) at the final visit were significantly different between the nine patients with EPTSs and the 69 patients who did not have EPTSs via the Mann-Whitney U-test. Statistically significant differences were identified in the type of brain trauma, treatment type, marital status, glucose level at HD#1, GCS at admission, GCS at discharge, and mRS at the final visit by the Mann-Whitney U-test between the 18 patients who developed PTE and the 60 patients who did not develop PTE. Conclusion: The patients with PTSs and PTE were relatively younger and were more likely to be unmarried. It is premature to draw a firm conclusion, but more active administration and long-term meticulous follow-up may be needed for young, highly educated, unmarried male patients. In addition, the analysis of more patients over a longer period of time will be needed.
Transcatheter aortic valve implantation with self-expandable prosthesis in the Republic of Moldova. The one year follow-up of the first ten patients
Authors:   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Abras Marcel , Surev Artiom ,   Institute of Cardiology, the Republic of Moldova, Moscalu Vitalie ,   Institute of Cardiology, the Republic of Moldova, Ciobanu Nicolae ,   Institute of Cardiology, the Republic of Moldova, Pasat Ecaterina ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova, Beiu Catalina ,   Nicolae Testemitanu State University of Medicine and Pharmacy, Republic of Moldova
Published: June 2022

Aortic stenosis (AS) is a valvular heart disease commonly found in the elderly patients. Treatment should be initiated prompt after the diagnosis of symptomatic AS, due to its poor prognosis and a high death rate. Transcatheter aortic valve implantation (TAVI) is the elective treatment for elderly patients with AS and high surgical risk. This study aims to evaluate the preand post-TAVI echocardiographic parameters and the major adverse cardiovascular events (MACE) within the first 30 days and at 1 year, in the first 10 patients subjected to TAVI in the Republic of Moldova.
Device and surgical treatment of patients with heart failure based on the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
Authors:   Institute of Cardiology, the Republic of Moldova, Moscalu Vitalie , Racila Valentin ,   Institute of Cardiology, the Republic of Moldova, Rizov Mihail ,   Institute of Cardiology, the Republic of Moldova, Gutan Inesa ,   Institute of Cardiology, the Republic of Moldova
Published: June 2022

Management of all patients with heart failure and reduced left ventricular ejection fraction is based on optimal drug treatment - „the great four” that reduce mortality (1-angiotensin converting enzyme inhibitors or angiotensin receptor neprilyzine inhibitor; 2-beta-adrenoblockers; 3-mineralocorticoid receptor antagonists; 4-sodium-glucose cotransporter inhibitors-2). For certain categories of patients, treatments with implantable cardiac devices (CRT-P/D or ICD) and cardiac surgery (coronary artery bypass grafting, aortic or mitral valve repair operations) that improve the life prognosis are required, and for advanced heart failure may be considered methods of mechanical circulatory support and heart transplantation.
Covid-19 disease and SARS-COV-2 vaccines: the balance between risks and benefits
Authors:   Institute of Cardiology, the Republic of Moldova, Sapojnic Nadejda , Bitca Angela ,   Institute of Cardiology, the Republic of Moldova, Durnea Aliona ,   Institute of Cardiology, the Republic of Moldova, Caraus Alexandr ,   Institute of Cardiology, the Republic of Moldova, Moscalu Vitalie ,   Institute of Cardiology, the Republic of Moldova
Published: June 2022

The infection with the new SARS-CoV-2 coronavirus has caused more than 4.5 million victims worldwide, and this number continues to rise. As more than 3 billion people have been vaccinated, COVID-19 vaccines shown an excellent efficacy and an acceptable safety profile. With the availability of SARS vaccines for an increasing number of people, several sporadic cases of adverse events have been reported, suggesting a causal relationship between these two phenomena. However, when it comes to the safety profile of SARS-CoV-2 vaccines, an important issue is that these risks should be balanced against the risks of exposure to COVID-19, an infection which itself can lead to lung damage but also to thrombotic /thromboembolic events. Increased risk of hematological and vascular events leading to hospitalization or death at short intervals after the first doses of ChAdOx1 nCoV-19 and BNT162b2 vaccines has been observed. Myocarditis is a very rare side effect associated with the BNT162b2 vaccine, which is 6-folds more likely to occur after SARS-CoV-2 infection compared to the vaccine itself. The risks of most of these events were substantially higher and more prolonged after SARS-CoV-2 infection than after vaccination in the same population.
Arterial hypertension and Diabetes: Coexistence of two medical conditions (aspects of pathophysiology and management)
Authors:   Institute of Cardiology, the Republic of Moldova, Popescu Liuba , Moiseeva Anna ,   Institute of Cardiology, the Republic of Moldova, Durnea Aliona ,   Institute of Cardiology, the Republic of Moldova, Caraus Alexandru ,   Institute of Cardiology, the Republic of Moldova
Published: June 2022

Hypertension and diabetes are two cardiovascular diseases which frequently coexistence, are high prevalence is likely to continue increasing considerably, influences on increasing of global cardiovascular risk and results with important clinical and social determinants. Treatment goals can be individualized in a stepwise approach, including lifestyle modification, psychosocial factors, risk factor treatment, and social determinants, targets and goals for LDL-C, BP, and glycaemic control.
SIMULATION OF PARAMETERS OF A COUPLING DEVICE
OF A MEASURING RESONATOR WITH A MICROWAVE PATH
Authors: BOGUSH V. , RODIONOVA V. , TANANA O.
Published: June 2022

An electrodynamic simulation of a device for coupling a cavity resonator with a path is performed. The cavity coupling device is a distributed communication line, i.e. associated with both the magnetic and electric fields of the resonator, and makes it possible to obtain a coupling that depends little on the frequency. An algorithm for approximating the values of the input impedance from the resistance of the coupling element has been developed in order to calculate the set of characteristics of the loaded resonator. The performed calculations and the obtained dependences make it possible to determine the geometrical parameters of the design of a broadband cavity resonator coupling device in the microwave range of wavelengths.
ACCUMULATION OF RADIONUCLIDES IN REPLACEABLE PARTS AND WATER TARGET CYCLOTRON
Authors: KIYKO A. , VABISHCHEVICH S. , VABISHCHEVICH N. , BRINKEVICH D.
Published: June 2022

The accumulation of unwanted long-lived radionuclides during the production of 18F-based radiopharmaceuticals using the IBA Cyclone 18/9 HC cyclotron is considered. Using high-resolution gamma-ray spectrometry with HPGe detectors, the identification of radionuclides and the assessment of activity in activated components (stripper, target entrance window) of the "medical" 18-MeV cyclotron IBA Cyclone 18/9 were carried out. More than 20 unwanted radionuclides have been identified in irradiated water. Various mechanisms for the entry of longlived radionuclides into irradiated water are described. The results obtained are of great importance for optimizing the methods of radioactive waste management in the production of radiopharmaceuticals and, as a result, minimizing the radiation exposure of personnel.
ELECTROMAGNETIC METHODS OF SEARCHING AND DEFINITION OF HYDROCARBON DEPOSITS
Authors: YANUSHKEVICH V. , ALIEVA S. , KALINTSEV S.
Published: June 2022

The article studies the characteristics of an anisotropic medium over hydrocarbons with the complex use of electromagnetic geo-exploration methods. The simulation of the components of dielectric permittivity tensors in the mode of amplitude-modulated, frequency-modulated, amplitude-frequency-modulated and radio pulse signals is carried out. The frequencies of the electron plasma and electron cyclotron resonances for the specified regimes are established. A study was made of the influence of modes of probing signals on the characteristics of an anisotropic medium above deposits and the components of the dielectric tensor. The effect of particle concentration variation on the real components of the components of the dielectric permittivity of an anisotropic medium above the UVZ is analyzed. Recommendations are given for improving the methods of electrical exploration and their application for prospecting geophysics.
PANCREATITE AGUDA: UMA REVISÃO NARRATIVA DA LITERATURA
Authors: Fernandes Ribeiro de Carvalho Pérola , Queiroz Leite Cleber , Brigida Matos de Carvalho Lucielly , Maria Rodrigues Couto Iara , Julia Gondim Bernardino Ana , Gonçalves da Silva Lima Karollyne , Flores Alencar Yanni , Duarte Cruz Vanessa , Rocha da Cruz e Silva Yara , Barbosa Pires Bárbara , Eduarda Brotto de Souza Maria , Carolina Diniz Mendes Ana , França dos Santos Brian
Published: June 2022

Introdução: A pancreatite aguda é caracterizada por uma inflamação de variadas etiologias sendo as principais colelitíase e etilismo. A prevalência da inflamação, no Brasil, encontra-se por volta 15,9/100.000. Diante dessa situação o objetivo desse estudo é descrever a fisiopatologia, manifestações clínicas, diagnóstico laboratorial, possíveis complicações sistêmicas e locais, bem como o tratamento da pancreatite aguda. Metodologia: Utilizou-se artigos com texto completo disponíveis nas bases de dados Google Acadêmico, Biblioteca Virtual em Saúde e PubMed. Resultados: 19 artigos foram identificados no período de estudo, todos com publicação de 2012 a 2022. Contudo, notou-se que o consumo abusivo de álcool apresenta implicações importantes na saúde pública em nível nacional e mundial, sendo essa etiologia causadora de 30% das pancreatites agudas, atingindo, em sua maioria, homens jovens com histórico de etilismo abusivo. Dessa forma, uma estimativa em nível global evidenciou que cerca de 237 milhões de homens e 46 milhões de mulheres são afetados com enfermidades relacionados ao uso abusivo de álcool. Conclusão: O diagnóstico da Pancreatite aguda deve ser clínico-laboratorial, sendo que o manejo inicial do paciente visa tratamento dos sintomas e voltado ao suporte, visto que ainda não há relatos conclusivos voltados a cessar a progressão da doença.
Dialectical View on HPWS and Its Outcomes
Authors: Pavlova Oksana
Published: June 2022

Purpose: The article is aiming to define the concept of HPWS and identify possible outcomes.

Study design/methodology/approach: study is designed to analyze the concept of HPWS and to identify the possible outcomes of HPWS. Method of scientific systematic literature review.

Findings: New forms of HRM and HRM systems are broadly discussed in various scenarios, but mostly with a focus on positive outcomes such as performance-enhancing, employee engagement, organizational affective commitment etc. Nevertheless, all novelties can have as many negative outcomes as positive, but it can be addressed, measured, and assessed only after some time.

Originality/value: HPWS entered the field in the ’90s and now it is about time to start applying the critical approach in order to understand that HPWS is not universal, it has many variations, many HRM items and different outcomes.
Malaria diagnosis using microscopic imaging
Authors: Sangole Mosam K. , Gandhe Sanjay T.
Published: June 2022

Malaria, a dangerous disease caused by Plasmodium, which is spread by being bitten by infected mosquitoes (Female Anopheles). It is crucial to diagnose malaria pathogens quickly and accurately at the right time. Traditional microscopy is commonly used in developing countries to diagnose malaria parasites, where pathologists examine the slide under a light microscope. However, in the case of traditional microscopy, requires more time and careful attention. Here, we have proposed a method to diagnose malaria based on computer vision. As a pre-processing stage, SAMF (Systematically Applied Mean Filter) algorithm is proposed that removes impulse noise from the corrupted malaria-infected images. Otsu method is used to obtain the binary version of images for cropping blood cells from complete image. 17 texture and color features were extracted from these cropped cells and these features were used to train Cubic SVM (Support Vector Machine) classifier. Hence a precise malaria diagnosis system was developed for detecting Plasmodium parasites, identifying their life stages and species using images of thin blood smears. A total of 348 images from CDC (Centre for Disease Control and Prevention) database were used to train and test the performance of the system.
Industrial and trade activities
Authors: Devi M. Durga , Thomas C.
Published: June 2022

In A.D 1763 the Nawab of Arcot, Muhammed Ali assigned Chingleput as a jahir to the English East India Company. When the company took over the jagir in 1782 under their direct administration Agriculture was the main occupation of the people. Next to agriculture the industrial activities, particularly the spinning and weaving, played an important role in the economic transactions of the Jagir area. These were also potters and fishermen, barbers and washer men. The Chetties, Kavaris and Komatis participated in Trade. Fishing played a decisive role in the life of the people who lived in the coastal areas. In1798 putting the fish market of Santhome, Vapery and Chintadripet with the weight and measures under Police committee. This weight and measure follows to the         northward. The salt revenue was also susceptible of considerable augmentation but unless assistance was afforded in the disposal of it by transportation to Bengal on account of the Company, there would be little use in extending the manufacture.
PROTOCOLO DE AVALIAÇÃO RÁPIDA: UMA PROPOSTA PARA RIOS URBANOS
Authors: Campos Janaina Cassia , Nucci João Carlos
Published: June 2022

Não há contestação para o fato de que as ações antrópicas alteram a natureza, mas há muito ainda para compreender sobre os impactos dessas ações. Os espaços urbanos ultrapassam, em sua maioria, a resiliência do meio em que estão inseridos, gerando impactos ambientais negativos irreversíveis. Entender como a paisagem reage às alterações antrópicas, bem como suas aptidões e limitações, é fundamental para o planejamento e gestão territorial. Assim, o objetivo deste estudo foi propor uma chave de avaliação da qualidade de rios urbanos, na forma de um Protocolo de Avaliação Rápida de Rios (PAR), baseada em uma abordagem holística do ecossistema fluvial. Nos resultados estão detalhados os critérios que compõe o PAR e respectivos parâmetros indicativos da condição do rio, classificada em boa, regular ou ruim. Os PARs são uma ferramenta de fácil entendimento e aplicação, que pode ser utilizada por órgãos ambientais, bem como pela sociedade em geral, promovendo a participação social de forma ativa sobre a governança da água.
A EMERGÊNCIA DE UM NOVO PARADIGMA PARA PRESERVAÇÃO DO TERRITÓRIO DA PECUÁRIA FAMILIAR NO PAMPA BRASILEIRO
Authors: Netto Tatiane Almeida , Azevedo Letícia Fátima de
Published: June 2022

Este estudo discute questões relacionadas aos conflitos territoriais, na presença de um rural reconfigurado e diverso na premissa do desenvolvimento rural sustentável frente à um paradigma agroecológico. Apresenta estratégias agroecológicas que promovem a permanência do pecuarista familiar fortalecendo seus laços com o ecossistema, sua produção e seu modo de vida. Os instrumentos de pesquisa utilizados foram a pesquisa bibliográfica e empírica das metodologias e estratégias agroecológicas que abrangem os conceitos que norteiam a pesquisa: agroecologia, pecuária familiar e ecossistema Pampa. Para tanto, foi realizada uma visita técnica em uma unidade demonstrativa do Projeto RS Biodiversidade, localizada em Santana do Livramento-RS, com foco no pastoreio rotativo, entrevista junto ao proprietário-produtor e o técnico da Emater responsável pela execução da atividade. Como resultados destaca-se o incremento da eficiência produtiva e a promoção da conservação ambiental no Pampa, utilizando recursos locais e provocando a eficiência do agroecossistema para a preservação da pecuária familiar.
COR E RIMA NA CIDADE CINZA: IDENTIFICANDO TERMINAIS DE CONEXÃO E ESPAÇOS DE REFERÊNCIA DO MOVIMENTO HIP-HOP NA PAISAGEM DE PONTA GROSSA – PR
Authors: Adami Lucas Renato , Nabozny Almir
Published: June 2022

O presente trabalho explora meios de leituras do movimento hip-hop na paisagem urbana de Ponta Grossa – PR. A dimensão metodológica a partir das representações sociais é apresentada como meio e forma de organização das narrativas dos ativistas do hip-hop (grafiteiros e rappers). Entre a teoria e a empiria a paisagem do movimento hip-hop é vista como texto de auto representação e ao mesmo tempo uma forma de leitura do movimento, expresso e constituído por terminais de conexão e espaços de referência que incorporam na escrita da paisagem a dimensão do lugar dos sujeitos. A compreensão da presença do movimento hip-hop na paisagem é representada por materializações e perspectivas simbólicas que ressignificam espaços e lugares, transformando a dimensão imagética e o próprio movimento, apresentando a paisagem composta por intertextualidades (DUNCAN, 1990; 2004). Em termos operacionais a observação participante e o diário de campo foram complementados por entrevistas narrativas que possibilitaram a elaboração de um núcleo central da representação como processo de sistematização dos dados. Como resultados destacam-se a identidade de grupo entrelaçada pelas ações de rappers e grafiteiros à uma esfera simbólica da representação (profissionalização x lazer) as quais estão ancoradas a ausência de cor na cidade, a fuga do cotidiano monótono e à preocupação social com relação ao acesso popular a arte (centro x periferia).
DESAFIOS NA GESTÃO AMBIENTAL PARTICIPATIVA EM UNIDADES DE CONSERVAÇÃO, BRASIL
Authors: Silva Maria do Socorro Ferreira da , Anunciação Vicentina Socorro da , Araújo Hélio Mário de
Published: June 2022

Esse ensaio visa refletir sobre os entraves que dificultam a Gestão Ambiental a luz do processo participativo em Unidades de Conservação (UCs). A pesquisa partiu de uma reflexão teórico-metodológica realizada com base em análise bibliográfica e documental, bem como diálogos com gestores de UCs. Os usos diversos estabelecidos nos territórios das UCs têm gerado conflitos socioambientais que dificultam a Gestão Ambiental das unidades e colocam em risco sua biodiversidade e o modo de vida das comunidades tradicionais. Parte das UCs foi decretada como Área de Proteção Ambiental, categoria estabelecida pelo SNUC, grupo de Uso Sustentável, onde são permitidos usos diversos que têm resultado na dilapidação dos recursos naturais. A escassez de recursos financeiros e humanos está entre os principais entraves que dificultam, enfraquecem e/ou impedem a Gestão Ambiental. É fundamental rever as categorias, canalizar recursos financeiros, qualificar os gestores e demais funcionários das UCs. Para alcançar a gestão participativa, com princípios voltados para a Educação Ambiental crítica, sugere-se a criação de estratégias para dirimir os conflitos, evitar à perda da biodiversidade e dar voz as comunidades tradicionais, que contribuíram com a conservação das florestas, e, demais grupos vulneráveis que sofrem com a injustiça ambiental e são excluídos dos processos decisórios.