bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Mini Clinical Evaluation Exercise (Mini-CEX) for post-graduate students in Prosthodontics: Student and Faculty Perceptions
Authors: Deshpande Saee , Pande Neelam , Radke Usha , Jaiswal Priti , Rathi Akhil , Sahni Shraddha
Published: January 2018

This article was migrated. The article was not marked as recommended. Background: The mini Clinical Evaluation Exercise or mini-CEX is method for simultaneously assessing the clinical skills of trainees and offering them feedback on their performance. Although it is a well established method of assessment for medical residents, in dental education are very scanty especially in post-graduate education.The aim of this study was to train the faculty for the use of Mini CEX in training post-graduate students in Prosthodontics and evaluate their perceptions regarding this novel assessment method. Methodology: Faculty training was carried out by conducting a workshop consisting of pre-test, video demonstration, small group discussion and post-test. Total 5 faculty members evaluated 12 postgraduate students in seven competency domains on 9 point likert scale on standard miniCEX form. Focused group discussion was carried out with students and faculty to evaluate their perceptions regarding the exercise. Results: there was a statistically significant improvement in cognitive knowledge by comparing the pretest and posttest results (7 ± 4 and 17 ± 2 respectively, p<0.0001)Total 82 encounters were recorded by 5 faculty members and 12 postgraduate students. All seven competencies were evaluated. Mean time for observing students by evaluator was 15.25 min and evaluator giving feedback was 11.20 min. Students ratings for satisfaction with the format (mean) were 8.34 and evaluator 7.23. Main themes emerging from focus group discussions were constructive feedback, objectivity and useful for exam preparation. Conclusions: Data from this study supports the use of mini CEX for post-graduate training in Prosthodontics. It is a cost effective way of assessing and giving constructive feedback to the students in structured manner. Further studies in different settings are needed to generalize its use in routine post-graduate training.
The introduction and evaluation of a consultant led formative OSCE (F-OSCE)
Authors: Jeffreys Sam , Vallabhaneni Pramodh
Published: January 2018

This article was migrated. The article was not marked as recommended. Background & AimsThe use of OSCEs as a tool to examine students has been extensively evaluated and they are now seen as the gold standard in examination tools in the examination of medical and allied health students throughout the world. As part of the Child Health attachment at Swansea University Medical School, a formative OSCE has been introduced as a teaching method. This also aids in exposing students to an OSCE in a non-simulated Paediatric environment for the first time. The aim of this study is to evaluate whether students find the formative OSCE a helpful teaching tool.MethodsAn online questionnaire was send to students following their five week specialty attachment. Responses to the survey were voluntary and anonymous. The survey explored student's attitudes before and after the formative OSCE.Results47 students responded out of 69. Overall, students reported a high level of satisfaction with the formative OSCE. 95% found it useful to their learning, with 89 % stating their knowledge improved following the formative OSCE. 100% described the feedback they received immediately following their OSCE as helpful while 65% reported feeling anxious prior to their OSCE.ConclusionIt can be concluded the formative OSCE was a successful aid to assess students. Majority reported positive experiences and felt that the formative OSCE aided their learning. Students suggested similar assessments would be beneficial in other specialty attachments. Formative OSCE's, when conducted in ideal environment, can fulfill both regulatory and supervisory requirements.
Estrogen Receptor-Positive Breast Cancer: Exploiting Signaling Pathways Implicated in Endocrine Resistance
Authors: Brufsky Adam M. , Dickler Maura N.
Published: January 2018

Advancements in molecular profiling and endocrine therapy (ET) have led to more focused clinical attention on precision medicine. These advances have expanded our understanding of breast cancer (BC) pathogenesis and hold promising implications for the future of therapy. The estrogen receptor-α is a predominant endocrine regulatory protein in the breast and in estrogen-induced BC. Successful targeting of proteins and genes within estrogen receptor (ER) nuclear and nonnuclear pathways remains a clinical goal. Several classes of antiestrogenic agents are available for patients with early, advanced, or metastatic BC, including selective ER modulators, aromatase inhibitors, and a selective ER degrader. Clinical development is focused upon characterizing the efficacy and tolerability of inhibitors that target the phosphatidylinositol 3 kinase (PI3K)/akt murine thymoma viral oncogene (AKT)/mammalian target of rapamycin inhibitor (mTOR) signaling pathway or the cyclin-dependent kinase 4/6 (CDK4/6) cell cycle pathway in women with hormone receptor-positive, human epidermal growth receptor 2-negative BC who have demonstrated disease recurrence or progression. De novo and acquired resistance remain a major challenge for women with BC receiving antiestrogenic therapy. Therefore, sequential combination of targeted ET is preferred in these patients, and the ever-increasing understanding of resistance mechanisms may better inform the selection of future therapy. This review describes the intricate roles of the PI3K/AKT/mTOR and CDK4/6 pathways in intracellular signaling and the use of endocrine and endocrine-based combination therapy in BC.

Implications for Practice

The foundational strategy for treating hormone receptor-positive, human epidermal growth receptor 2-negative, advanced breast cancer includes the use of endocrine therapy either alone or in combination with targeted agents. The use of combination therapy aims to downregulate cell-signaling pathways with the intent of minimizing cellular “crosstalk,” which can otherwise result in continued tumorigenesis or progression through redundant pathways. This review provides the clinician with the molecular rationale and clinical evidence for these treatments and refers to evidence-based guidelines to inform the decision-making process.
КОНЦЕПТУАЛЬНАЯ ОСНОВА ПОЛУЧЕНИЯ И ИССЛЕДОВАНИЯ МАКСИМАЛЬНОГО ВРЕМЕНИ ПРОГНОЗА С ЗАРАНЕЕ ЗАДАННОЙ ТОЧНОСТЬЮ
Authors: Kumratova A. M.
Published: January 2018

Цель: системно обобщающая комбинация моделей кластерного анализа и моделей конкордации Кенделла для агрегации значений частных прогнозов, доставленных разными методами и подходами. Обсуждение: в работе введено понятие «прогнозируемости» временных рядов различной природы, в котором впервые обоснован императив, связывающий длину горизонта прогноза, заданное качество прогноза и статистические и фрактальные характеристики прогнозируемого процесса. Математическая постановка задачи, а также модели, методологии и способы оценки степени «прогнозируемости», инструментальные и программные средства должны иметь реализующие их алгоритмы и инструменты, которые входят в состав профессиональных систем компьютерной математики. Результаты: проблемы количественной оценки «прогнозируемости» автор предлагает напрямую связать с длиной «горизонта будущего». Они имеют целью получение a priori оценки долготы и качества прогноза в зависимости от статистических свойств прогнозируемого сигнала при наперёд заданной точности.
МИРОВОЙ РЫНОК ТРУДА: ПРОБЛЕМЫ И ТЕНДЕНЦИИ РАЗВИТИЯ
Authors: Dorokhova N. V.
Published: January 2018

Цель: выявление на основе анализа статистических данных основных проблем и тенденций развития мирового рынка труда. Обсуждение: мировой рынок труда выступает важным элементом мирового хозяйства. От его конъюнктуры во многом зависит динамика экономического роста. Новый характер социально-трудовых отношений формирует ряд проблем, препятствующих поступательному развитию мирового рынка труда и требующих тщательного исследования. Результаты: в ходе исследования выявлены основные проблемы и тенденции развития мирового рынка труда: рост числа безработных, неформально занятых, рост гибкости занятости с одновременным сокращение социальных гарантий и т.д. Обосновано существенное влияние мирового рынка труда на функционирование и развитие национальных рынков.
40 years of Bio-Psycho-Social model: what’s new?
Authors: Kholmogorova A.B. , Rychkova O.V.
Published: January 2018

Bio-Psycho-Social Model, proposed by George Engel in 1977, was recognized as a turning point in the praxis of medical diagnosis and treatments. Bio-Psycho-Social Model should be seen in a historical context as bucking against the trend of biological reductionism. Social Neuroscience has been formed ten years. Social neuroscience aims to investigate the biological systems that underlie people’s thoughts, feelings and actions in light of the social context in which they operate. Social neuroscience has captured the interest of anthropologists, psychiatrists, psychologists, and experts in other disciplines, as well as the general public who more and more draw upon the insights and methods of social neuroscience to explain, predict and change social behavior. An analysis of the current situation in neurosciences shows that new methods of instrumental brain research do not exclude biological reductionism. The authors qualify the situation in modern studies of social neuroscience as a methodological crisis associated with the prevalence of reductionist approaches that ignore the uniqueness of the human psyche. He substantiates the heuristic provisions of the cultural and historical development of Vygotsky’s psyche theory to overcome any contradictions
The Use of Restoring Resources of the Survival Roles and Reflex Patterns in MNRI® (Reflex Integration) Interactive Training of Personality Growth and Interpersonal Relations
Authors: Masgutova S.K. , Shackleford P. , Masgutov D.R.
Published: January 2018

Personality growth as a socio-psychological problem is a multi-complex phenomenon that targets Self-identity, Self-actualization, and other areas. During the last decade scientists started studying other factors limiting the personality growth, such as stress and post-trauma. However, the Survival Roles, the socio-individual patterns based on neurophysiological and psychological defense mechanisms blocking the personality Self-actualization, social interaction and professional business qualities, are rarely discussed. Thus this study based on Survival Roles may extend the personality growth oriented concepts and therapy modality tools. This study showed a correlation between Survival Role patterns, stress resilience, and survival reflexes (integrative units of the nervous system functions). Comparative data on 464 business professionals from high management jobs (Study Group — n=340, and Control Group — n=124) participated in this research which found 70.9 % (n=329) of the total group was in stress. This stress activated socio-individual Survival Roles and protective reflex patterns which responded with reactivity, over-protection, non-constructive interactions with others and limited business strategies. The MNRI® reflex integrative training used in this study demonstrated improvement of functions of the protective reflex patterns effected positively the survival mechanisms including increased stress resilience, and decreased negative effect of Survival Roles. MNRI® proposes a new paradigm in the realm of personality growth and socio-interpersonal activity, and supports the neurophysiological aspects to optimize the overall quality of life of business professionals from a variety of high management business areas.
3D printing of hydrogel composite systems: Recent advances in technology for tissue engineering
Authors: Jang Tae-Sik , Jung Hyun-Do , Pan Houwen Matthew , Han Win Tun , Chen Shengyang , Song Juha
Published: January 2018

Three-dimensional (3D) printing of hydrogels is now an attractive area of research due to its capability to fabricate intricate, complex and highly customizable scaffold structures that can support cell adhesion and promote cell infiltration for tissue engineering. However, pure hydrogels alone lack the necessary mechanical stability and are too easily degraded to be used as printing ink. To overcome this problem, significant progress has been made in the 3D printing of hydrogel composites with improved mechanical performance and biofunctionality. Herein, we provide a brief overview of existing hydrogel composite 3D printing techniques including laser based-3D printing, nozzle based-3D printing, and inkjet printer based-3D printing systems. Based on the type of additives, we will discuss four main hydrogel composite systems in this review: polymer- or hydrogel-hydrogel composites, particle-reinforced hydrogel composites, fiber-reinforced hydrogel composites, and anisotropic filler-reinforced hydrogel composites. Additionally, several emerging potential applications of hydrogel composites in the field of tissue engineering and their accompanying challenges are discussed in parallel.
Application of a distributed 2D overland flow model for rainfall/runoff and erosion simulation in a Mediterranean watershed
Authors: Juez C. , Tena A. , Fernández-Pato J. , Batalla R.J. , García-Navarro P.
Published: January 2018

Soil erosion has reemerged as an environmental problem associated with climate change that requires the help of simulation tools for forecasting future consequences. This topic becomes even more relevant in Mediterranean catchments due to the highly variable and irregular rainfall regime. Hence, an approach that includes the rainfall/runoff and erosion phenomena is required for quantifying the amount of soil the catchments are transferring to the rivers. As the calibration process of the infiltration and erosion parameters can become cumbersome in terms of iterations to the optimal values to fit experimental data, a Simplified Catchment Model (SCM) is introduced as a first approach. The set of tuning constants that provides the best fit are used as input for re-calibrating the parameters by means of the simulation of the real catchment. The modeling effort here presented opens its application to the analysis of the hydro-sedimentary processes at larger temporal and spatial scales.
Rainfall extremes modeling under shortage of data and uncertainty in the Pampean region (Argentina)
Authors: Puricelli M.
Published: January 2018

The assessment of the surface runoff capacity of storms is essential for the design of drainage infrastructure, for the management of rainfall excesses and the control of soil erosion. The knowledge of precipitation intensity values at scales larger than the daily is a key in this process. However, the available information in the region is reduced, due to the lack of instruments and historical data. An alternative to solve this problem consists of the search of mathematical relations for the scale change from daily values, more common and available, to sub-hourly values, necessary for the estimation of runoff volumes in small basins as well as erosive power of rainfall. The first results obtained in the experimentation and search of mathematical relations for the change of temporal scale for values of intensity of precipitation, valid for a wide territory with clear climatic and ecological variability are presented in this paper. The main objective of this work was to investigate the property of scale invariance in rainfall intensity and its application to the construction of IDF curves by simple scaling. The regionalization of the values obtained in the areas of study was established as a complementary objective. The hypothesis of the scale invariance and the possibility of applying simple scaling to precipitation intensity values have been verified using both pluviographic and pluviometric data recorded over the Argentina's Pampean region in climatically and ecologically different localities. The present work provides the criteria and reference values for the construction and updating of the IDF curves in the region, where they are highly necessary, leading to advances in hydrology in areas with little or no rainfall information. The results provide new evidence on scaling relations in hydrological variables, which are useful for application in cases where reference information is scarce. This contributes to the knowledge of local precipitation characteristics and provides reference values to be used in practical applications.
What have we learnt about Mediterranean catchment hydrology? 30 years observing hydrological processes in the Vallcebre Research Catchments
Authors: Llorens P. , Gallart F. , Cayuela C. , Roig-Planasdemunt M. , Casellas E. , Molina A.J. , Moreno de las Heras M. , Bertran G. , Sánchez-Costa E. , Latron J.
Published: January 2018

This paper presents the main results obtained from the study of hydrological processes in the Vallcebre Research Catchments since 1988. Distributed hydrometric measurements, environmental tracers and hydrological modelling were used to understand Mediterranean catchment behaviour and to provide new data to help assess the global change effects on these catchments' water resources. Thirty years of hydrological processes observation in the Vallcebre Research Catchments have increased understanding not only of their hydrological response, but also of the main hydrological and erosion processes characteristic of Mediterranean mountain catchments. This paper briefly summarises the main results obtained since 1988 on ecohydrological processes, hydrological response, runoff generation processes, erosion and sediment transport. Some of the main findings from this research are (i) the importance of temporal variability in precipitation to determine the hydrological processes; (ii) the paramount role played by forest cover in reducing soil water content; (iii) the marked influence of antecedent wetness conditions on runoff generation that determine different runoff responses; (v) the dominant contribution of pre-existing water during floods; (vi) the importance of freezing-thawing processes in badland areas on erosion and the role of summer convective storms in controlling sediment transport.
Facing loss: coping mechanisms of Mayan widows in Guatemala
Authors: Kaupisch Patricia
Published: January 2018

In countries of the global south the rights of widows are repeatedly infringed and neglected both by the women’s movement and by the international humanitarian community. Widows in Guatemala suffer especially from lack of official recognition and the psychological consequences of not knowing the fate of their husbands or not being able to bury them or remarry. This article focuses on Mayan Widows in Guatemala and how they cope with the loss in the context of the former military dictatorship and its counterinsurgency campaign against Guatemala’s rural, and mostly Indian citizens, the so-called “la violencia”. The study examines the psychological pain, coping mechanisms of these women and how they fulfil their dual economic roles; their vulnerability to intimidation, violence or abuse; and how this situation redefines their behaviour.Published online: 11 December 2017
TRINIDAD REQUENA, Antonio y Mariano SÁNCHEZ MARTÍNEZ (eds). 2016. Marcos de análisis de los problemas sociales. Una mirada desde la Sociología. Madrid: Catarata, 318 pp.
Authors: Benali Inam
Published: January 2018

Marcos de análisis de los problemas sociales es el resultado del trabajo de una treintena de sociólogos contemporáneos que forman parte de diferentes universidades españolas e internacionales, aunque liderado por el grupo de investigación: Los problemas sociales en Andalucía. Todos ellos unieron sus esfuerzos bajo un título que sugiere al lector que se va a encontrar ante un trabajo que trata los problemas sociales desde una perspectiva sociológica. Formado por 17 capítulos, cinco de los cuales son metodológicos y teóricos, mientras los capítulos analíticos se dividen en tres bloques temáticos: «espacio y vida social», «instituciones y procesos de la sociedad civil» y «dimensiones sociales de la vida económica».Publicación en línea: 11 diciembre 2017
Leitura: importância de despertar e desenvolver o gosto pelo hábito da leitura nos anos iniciais do ensino fundamental em uma escola pública de Boa Vista (RR)
Authors: Varela Simone Refkalefsky
Published: January 2018

O presente artigo tem como propósito apresentar a pesquisa realizada a partir das experiências vivenciadas em uma escola pública de Boa Vista-RR, onde oponto norteador foi a leitura, com foco na importância de despertar e desenvolver o gosto pelo hábito da leitura nos anos iniciais do Ensino Fundamental. A elaboração e execução de um projeto de intervenção foi o ponto essencial para o desenvolvimento desse projeto. Nessa perspectiva o trabalho tem como objetivo de analisar e contribuir efetivamente para o desenvolvimento global da escola pública de Boa Vista, no que se refere às estratégias de leitura que favoreçam a formação de leitores durante a realização desse projeto. A metodologia utilizada na pesquisa compreendeu uma abordagem qualitativa, com procedimentos de coleta de dados: as observações, entrevistas e questionários, possibilitando a coleta de dados e a análise dos problemas de maneira mais adequada e relacionada aos objetivos propostos, possibilitando assim um contato mais direto com os sujeitos: equipe gestora, docentes e discentes. Oportunizando ainda um olhar reflexivo sobre a prática pedagógica na rede pública do Estado de Roraima.
O ambiente de uma praça pública: articulando saberes de forma coletiva
Authors: Brando Fernanda da Rocha
Published: January 2018

O presente trabalho versa sobre uma proposta de ação educativa, voltada para um projeto de extensão acadêmica junto à formação inicial de professores em Ciências Biológicas. A proposta está relacionada à construção do conhecimento de forma coletiva, articulando: ações em políticas públicas, o papel da comunidade na gestão de assuntos educativos e a aplicabilidade, em contextos da vida real, dos conhecimentos produzidos pela comunidade científica. Esta intervenção trata um espaço físico, a Praça Pública, como um universo de investigação, considerando tanto a integralidade quanto os aspectos mais específicos de seus elementos constituintes. Este “espaço” oferece aos diversos atores sociais envolvidos a possibilidade de engajamento em discussões, estudos, avaliação e proposição de projetos relativos à temática ambiental de forma qualificada. Com aefetivação desta proposta, espera-se que os atores sociais envolvidos compreendam de forma mais abrangente a conexão entre ciência, sociedade e ambiente.
Effect of phosphorus on the performance of greengram (Vigna radiata L) varieties during summer
Authors: Singh Vikram , Sharma S. K. , Thakral S. K. , Sharma M. K..
Published: January 2018

Field experiment was conducted at CCS Haryana Agricultural University KrishiVigyan Kendra, Ambala during summer season of 2014 to study the effect of phosphorus levels and varieties on growth, yield parameters, yield, economics and nutrient uptake of greengram. The experiment was laid out in randomized block design with two varieties of green gram viz. MH 421 and SML 668 and four phosphorus levels viz. control (no fertilizer), 20, 40 and 60 kg P2O5/ha with 4 replications. Cv.MH421 produced significantly higher seed yield (1158 kg/ha), yield attributing parameters, harvest index, attraction index, net returns (Rs 21001/ha), BC ratio (1.60) and nutrient uptake compared to SML 668 during summer season. Application of 40 kg P2O5/ha registered significantly higher seed yield (1283 kg/ha), yield attributing characters, harvest index, attraction index, net returns (Rs 32351/ha), BC ratio (2.08) and nutrient uptake of green gram compared to control and 20 kg P2O5/ha. However, 40 kg P2O5/ha and 60 kg P2O5/ha were at par with respect to majority of studied.
COMPORTAMIENTO SÍSMICO DE EDIFICIOS DE ACERO CON MARCOS PERIMETRALES RESISTENTES A MOMENTO
Authors: Reyes Salazar Alfredo , Bojórquez Mora Juan , Bojórquez Mora Edén , Velázquez Dimas Juan I. , Rodríguez Lozoya Héctor E.
Published: January 2018

Varios aspectos relacionados con la idealización estructural de edificios de acero con marcos perimetrales resistentes a momento y marcos interiores de gravedad (MGs) se abordan en esta investigación. El estudio numérico indica que la contribución de los MGs a la resistencia lateral puede ser significativa y que modelar los edificios como marcos planos puede resultar en elementos mecánicos, cortantes y desplazamientos de entrepiso más grandes que cuando se modelan en forma tridimensional, por lo que su diseño puede ser conservador. También se observa que el cortante de entrepiso promedio generalmente se incrementa cuando se considera la rigidez de las conexiones de los MGs. Los desplazamientos de entrepiso promedio son similares para los modelos con conexiones articuladas y semi-rígidas. Los resultados también indican que los momentos que las conexiones pueden transmitir son cercanos al 30 % de los momentos plásticos de las vigas a las que conectan. La diferencia entre los resultados se debe principalmente a los elementos que contribuyen a la resistencia y rigidez, la disipación de energía, y las características dinámicas de cada representación estructural. Se concluye que, si se usa la estructuración antes mencionada, el modelo tridimensional debe ser usado, que los MGs deberán considerarse como parte del sistema lateral resistente y que la rigidez de las conexiones deberá incluirse en el diseño de los MGs
ESTIMACIÓN DE PROPIEDADES DINÁMICAS DE ARCILLAS
Authors: González Blandón Claudia M. , Romo Organista Miguel P.
Published: January 2018

Se propone un procedimiento de modelación tipo Masing, para estimar los comportamientos no lineales de propiedades dinámicas de arcillas normalmente consolidadas. Estos comportamientos corresponden a las variaciones del módulo de rigidez al corte y de la relación de amortiguamiento respecto a la deformación angular. El procedimiento es producto de un análisis minucioso de las propuestas realizadas por Romo (1990, 1995) y Flores et al. (1999). Dicho análisis sustenta la necesidad de definir valores de la deformación de referencia y del parámetro B, para cada una de las propiedades dinámicas. Por ende, se puede concluir que la modelación del módulo de rigidez y de la relación de amortiguamiento, se debe realizar de manera independiente. Finalmente, se ilustra el procedimiento de modelación mediante un ejercicio de aplicación, en el que se obtienen las curvas G - γ y λ - γ de una muestra de arcilla de la Ciudad de México.
PRESIONES DINÁMICAS DEL SUELO EN LUMBRERAS
Authors: Avilés López Javier , Pérez Rocha Luis Eduardo
Published: January 2018

Se presenta un método de frontera para calcular las presiones del suelo y las fuerzas asociadas producidas por sismo en lumbreras profundas de gran diámetro. La respuesta del sistema ante incidencia vertical de ondas de cortante se construye mediante expansiones de modos de ondas usando el método del estrato delgado. La solución satisface rigurosamente las condiciones de compatibilidad (desplazamientos y fuerzas) entre suelo y lumbrera, así como las condiciones de superficie libre y basamento rígido. Para sistemas típicos, se evalúa la importancia relativa de la flexibilidad del muro y la condición de apoyo; se construye además un conjunto de tablas de diseño para calcular las distribuciones del cortante y momento con la profundidad.
ESTIMACIÓN DEL PELIGRO SÍSMICO DEBIDO A SISMOS INTERPLACA E INSLAB Y SUS IMPLICACIONES EN EL DISEÑO SÍSMICO
Authors: García Soto Adrián David , Pozos-Estrada Adrián , Hanping Hong , Gómez Martínez Roberto
Published: January 2018

La ocurrencia de grandes sismos causa excitaciones muy intensas del terreno que pueden provocar el colapso de edificios y puentes. Para tomar en cuenta la incertidumbre en esta ocurrencia y en las solicitaciones sísmicas de diseño, la evaluación probabilística del peligro sísmico es empleada para desarrollar espectros de peligro uniforme (EPU) y mapas de contorno de peligro sísmico. Aunque existe mucha información en relación al cálculo del peligro sísmico en México y su inclusión en reglamentos, no hay en la literatura un reporte detallado, que incluya un modelo de peligro sísmico útil para obtener los EPU, para desarrollar mapas de contorno, y para determinar respuestas inelásticas. Además, ya que la demanda de ductilidad de desplazamiento puede diferir para sismos interplaca e inslab, esta diferencia debería incorporarse en la estimación de la confiabilidad estructural. En este estudio se integra un modelo de peligro sísmico útil para estimar los EPU y para desarrollar mapas de contorno para una parte de México; se calcula la contribución al peligro sísmico de cada tipo de sismo; y se estima el nivel de carga sísmica requerido para diseño,considerando las diferencias en la demanda de ductilidad causada por sismos interplaca e inslab
PROCEDIMIENTO DE EVALUACIÓN DE EDIFICIOS DE CONCRETO REFORZADO BASADO EN DESEMPEÑO: DESARROLLO Y VALIDACIÓN
Authors: Mendoza Pérez Mabel , Ayala Milián Gustavo
Published: January 2018

Se presenta un método para evaluar sísmicamente edificios de concreto reforzado, fundamentado en conceptos de ingeniería basada en desempeño; en la validez de la curva de capacidad como una propiedad del sistema estructural; y en la consideración de energía disipada por histéresis, introducida en el procedimiento mediante tasas de amortiguamiento equivalente en un sistema simplificado de un grado de libertad. El método permite evaluar de manera directa el desempeño de estructuras sometidas a demandas sísmicas crecientes ya que conduce a una curva de capacidad que aproxima satisfactoriamente la correspondiente derivada de análisis dinámicos incrementales.
DISEÑO SÍSMICO DE MARCOS DE ACERO CONTRAVENTEADOS. PARTE 1: RECOMENDACIONES DE DISEÑO
Authors: Tapia Hernández Edgar , Tena Colunga Arturo
Published: January 2018

A fin de contribuir al conocimiento adquirido sobre el diseño sísmico de edificios estructurados con marcos momento resistentes dúctiles de acero contraventeados, se presenta una metodología de diseño por capacidad adaptada al Reglamento de Construcciones para el Distrito Federal (RCDF-04), que pretende establecer los requisitos mínimos que deben ser considerados en el diseño de este sistema estructural para que los mecanismos de colapso desarrollados concuerden con las premisas implícitas en el diseño (columna fuerte – viga débil – contraviento más débil), con una adecuada distribución de la respuesta inelástica en la altura y redistribuciones de cargas predecibles. La metodología, que incluye factores por ductilidad y sobrerresistencia más realistas para este sistema estructural, se ejemplifica en un modelo de 14 niveles diseñado en suelo blando.
UNA APROXIMACIÓN PARA LA OBTENCIÓN DE MAPAS DE DESPLAZAMIENTO TRASLACIONAL DE LADERAS A NIVEL REGIONAL INDUCIDO POR SISMOS
Authors: Jaimes Téllez Miguel A. , Niño Lázaro Mauro , Reinoso Angulo Eduardo
Published: January 2018

Se propone una expresión para estimar el desplazamiento de Newmark en términos de la relación entre la aceleración crítica, ac (umbral de aceleración del suelo para iniciar un movimiento del talud) y la aceleración máxima del suelo, amax, para obtener el deslizamiento traslacional de laderas por sismo que de manera aproximada estimen esta amenaza a escala regional. Con los resultados que se obtienen de la ecuación de desplazamiento propuesta es posible definir un mapa de peligro por deslizamiento traslacional a nivel regional inducido por sismos. Para llevar a cabo lo anterior, se asumen valores promedio de propiedades mecánicas del suelo como la cohesión, peso volumétrico y ángulo de fricción a partir de mapas geológicos y litológicos a escala 1:1’000,000, así como la pendiente de deslizamiento potencial a partir de modelos de elevación digital del terreno. Se presenta un mapa de peligro de deslizamiento de la República Mexicana asociado a la aceleración máxima del suelo que se presenta con un periodo de retorno de 150 años, y un ejemplo de un mapa empleando como detonador el sismo de Tecomán en Colima de magnitud M=7.6 ocurrido el 21 de enero de 2003; este ejemplo se compara con el obtenido a través del método Mora-Vahrson que es ampliamente utilizado para elaborar este tipo de mapas de deslizamientos
EFECTO DE LA ESBELTEZ EN LA RESISTENCIA DE MUROS DE MAMPOSTERÍA CONFINADA
Authors: Pérez Gavilán Juan José , Flores Corona Leonardo , Alcocer Martínez de Castro Sergio
Published: January 2018

Se presentan los resultados de un estudio experimental consistente en el ensayo de siete muros de mampostería confinada de barro a escala natural con relaciones de aspecto (H/L) que van desde 0.3 hasta 2.2. Se investigó el posible cambio de la rigidez lateral, antes del primer agrietamiento, con la carga vertical, y la degradación de la rigidez y resistencia laterales de los muros ante carga lateral cíclica. Los resultados muestran que la carga vertical y la relación de aspecto no tuvieron un efecto significativo en la rigidez lateral relativa a la teórica. Asimismo, que el comportamiento inelástico de los muros, caracterizado por medio de la degradación de la rigidez normalizada contra la demanda de ductilidad, puede estimarse, con buena precisión, con una función bilineal para valores de demanda de ductilidad hasta de 4.5. Se observó un incremento sustancial de la resistencia al agrietamiento normalizada con respecto a la resistencia nominal, con la reducción de la relación de aspecto. Se dedujo una expresión para estimar la resistencia al agrietamiento en función de la relación de aspecto, que coincide razonablemente con los resultados experimentales. Se propone una nueva expresión para el cálculo de la fuerza cortante de agrietamiento para diseño
Mesa Directiva
Authors: SMIS SMIS
Published: January 2018

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REGLAS DE COMBINACIÓN DE LOS EFECTOS DE LAS TRES COMPONENTES DE TERREMOTOS Y RESPUESTA CRÍTICA
Authors: Valenzuela Beltrán Federico , Reyes Salazar Alfredo , De León Escobedo David , Bojórquez Mora Edén , López Barraza Arturo
Published: January 2018

La precisión de las reglas de combinación del 30% y SRSS, y la orientación crítica de las componentes de terremotos se estudian en este trabajo. Se analizan modelos estructurales complejos que representan edificios de baja y mediana altura. Se realiza un análisis estadístico de la precisión de las reglas de combinación aplicadas a parámetros de respuesta individuales y múltiples. El efecto de la correlación entre las componentes de los terremotos en dicha precisión también se estudia. Finalmente, se realizan análisis con varios ángulos de incidencia de las componentes con la finalidad de encontrar la orientación crítica. Los resultados muestran que las reglas subestiman la carga axial en columnas, pero sobreestiman razonablemente los cortantes de entrepiso. Ambas reglas son más conservadoras cuando los modelos se excitan por las tres componentes. Los efectos individuales pueden estar altamente correlacionados, incluso para componentes principales no correlacionadas. Las reglas no siempre son precisas para valores pequeños de coeficientes de correlación, y valores altos de éstos no siempre están relacionados a una estimación imprecisa de la respuesta combinada. La precisión de las reglas de combinación depende del grado de correlación de las componentes, del parámetro de respuesta, de la localización del elemento considerado y del nivel de deformación estructural.Palabras clave: códigos de diseño sísmico; edificios de acero; reglas de combinación; correlación de los efectos individuales; respuesta crítica
TransPath: Representation Learning for Heterogeneous Information Networks via Translation Mechanism
Authors: Fang Yang , Zhao Xiang , Tan Zhen
Published: January 2018

In this paper, we propose a novel network representation learning model TransPath to encode heterogeneous information networks (HINs). Traditional network representation learning models aim to learn the embeddings of a homogeneous network. TransPath is able to capture the rich semantic and structure information of a HIN via meta-paths. We take advantage of the concept of translation mechanism in knowledge graph which regards a meta-path, instead of an edge, as a translating operation from the first node to the last node. Moreover, we propose a user-guided meta-path sampling strategy which takes users' preference as a guidance, which could explore the semantics of a path more precisely, and meanwhile improve model efficiency via the avoidance of other noisy and meaningless meta-paths. We evaluate our model on two large-scale real-world datasets DBLP and YELP, and two benchmark tasks similarity search and node classification. We observe that TransPath outperforms other state-of-the-art baselines consistently and significantly.
ESCOLA E SURDEZ: O QUE DIZEM PROFESSORES E PAIS A RESPEITO?
Authors: Lima Ezer Wellington Gomes , Senna Luiz Antonio Gomes
Published: January 2018

Em virtude ao enredamento que cerca a escolarização de surdos, a pesquisa teve como objetivo, levantar os espaços e funções da escrita no contexto familiar e escolar de crianças/alunos surdos, em processo de alfabetização, na tentativa de reconhecer como e para que usam a escrita. A partir da questão central da pesquisa, foi necessário focalizar o contexto escolar, as interações e o desempenho na língua portuguesa de aprendizes surdos, buscando os dados regulares e os singulares manifestados pelos sujeitos envolvidos. Dessa maneira, foi possível constatar que nem os pais nem os professores usam a língua de sinais para interagir com os surdos, gerando interações linguísticas restritas e pouco efetivas.  Outro aspecto importante deste estudo se situa na grande dificuldade e insegurança dos professores em trabalhar com alunos surdos: os profissionais, muitas vezes, relatam terem dúvidas se realmente estão conseguindo ensinar e se o surdo realmente está aprendendo. O que se apreende desse estudo é que a voz dos familiares, assim como do professor é fundamental para que algo possa ser pensado e/ou repensado em relação à escolarização desses sujeitos.
RELAÇÕES HISTÓRICAS ENTRE A EDUCAÇÃO AMBIENTAL E A PARTICIPAÇÃO SOCIAL
Authors: Festozo Marina Battistetti , Queixas Ricardo Campos , Nascimento Junior Antonio Fernandes , Tozoni-Reis Marilia Freitas de Campos
Published: January 2018

Recorremos à história para pesquisar as relações entre movimentações sociais e a concepção crítica da Educação Ambiental brasileira. Tomamos o materialismo histórico-dialético como referencial teórico-metodológico. Os dados resultam de pesquisa bibliográfica e de campo, entrevistando personagens da área de história ambiental e do ambientalismo europeu. Nossas pesquisas indicam que, em meio aos novos movimentos sociais, o movimento ambientalista assume novas críticas, ao uso de energia nuclear, à cultura política, aos modos de vida, etc. Estes movimentos contribuem com o aprimoramento da participação da sociedade e, portanto, com a sua formação política. O Brasil, apesar da longa história de exploração e tolhido por ditaduras, com o tempo, sintetiza ideais revolucionários locais e estrangeiros e se torna solo fecundo a um movimento crítico, inclusive na educação. A Educação Ambiental se fortalece junto a este movimento, articulando assim a questão ambiental à justiça, participação, emancipação social e sustentabilidade.
Estimating Alzheimer’s Disease Progression Rates from Normal Cognition Through Mild Cognitive Impairment and Stages of Dementia
Authors: Davis Matthew , O`Connell Thomas , Johnson Scott , Cline Stephanie , Merikle Elizabeth , Martenyi Ferenc , Simpson Kit
Published: January 2018

Background:

Alzheimer’s Disease (AD) can be conceptualized as a continuum: patients progress
from normal cognition to mild cognitive impairment (MCI) due to AD, followed by increasing
severity of AD dementia. Prior research has measured transition probabilities among later stages of AD,
but not for the complete spectrum.

Objective:

To estimate annual progression rates across the AD continuum and evaluate the impact of a
delay in MCI due to AD on the trajectory of AD dementia and clinical outcomes.

Methods:

Patient-level longitudinal data from the National Alzheimer’s Coordinating Center for
n=18,103 patients with multiple visits over the age of 65 were used to estimate annual, age-specific transitional
probabilities between normal cognition, MCI due to AD, and AD severity states (defined by
Clinical Dementia Rating score). Multivariate models predicted the likelihood of death and institutionalization
for each health state, conditional on age and time from the previous evaluation. These probabilities
were used to populate a transition matrix describing the likelihood of progressing to a particular
disease state or death for any given current state and age. Finally, a health state model was developed to
estimate the expected effect of a reduction in the risk of transitioning from normal cognition to MCI due
to AD on disease progression rates for a cohort of 65-year-old patients over a 35-year time horizon.

Results:

Annual transition probabilities to more severe states were 8%, 22%, 25%, 36%, and 16% for
normal cognition, MCI due to AD, and mild/moderate/severe AD, respectively, at age 65, and increased
as a function of age. Progression rates from normal cognition to MCI due to AD ranged from 4% to 10%
annually. Severity of cognitive impairment and age both increased the likelihood of institutionalization
and death. For a cohort of 100 patients with normal cognition at age 65, a 20% reduction in the annual
progression rate to MCI due to AD avoided 5.7 and 5.6 cases of MCI due to AD and AD, respectively.
This reduction led to less time spent in severe AD dementia health states and institutionalized, and increased
life expectancy.

Conclusion:

Transition probabilities from normal cognition through AD severity states are important for
understanding patient progression across the AD spectrum. These estimates can be used to evaluate the
clinical benefits of reducing progression from normal cognition to MCI due to AD on lifetime health
outcomes.
Prevalence, Correlates and Management of Hyperglycemia in Diabetic Non-critically Ill Patients at a Tertiary Care Center in Lebanon
Authors: El Khoury Ghada , Mansour Hanine , Kabbara Wissam K. , Chamoun Nibal , Atallah Nadim , Salameh Pascale
Published: January 2018

Background:

Diabetes Mellitus is a chronic metabolic disease that affects 387 million people
around the world. Episodes of hyperglycemia in hospitalized diabetic patients are associated with
poor clinical outcomes and increased morbidity and mortality. Therefore, prevention of hyperglycemia
is critical to decrease the length of hospital stay and to reduce complications and readmissions.

Objective:

The study aims to examine the prevalence of hyperglycemia and assess the correlates and
management of hyperglycemia in diabetic non-critically ill patients.

Methods:

The study was conducted on the medical wards of a tertiary care teaching hospital in Lebanon.
A retrospective chart review was conducted from January 2014 until September 2015. Diabetic
patients admitted to Internal Medicine floors were identified. Descriptive analysis was first carried out,
followed by a multivariable analysis to study the correlates of hyperglycemia occurrence.

Results:

A total of 235 medical charts were reviewed. Seventy percent of participants suffered from
hyperglycemia during their hospital stay. The identified significant positive correlates for inpatient hyperglycemia,
were the use of insulin sliding scale alone (OR=16.438 ± 6.765-39.941, p=0.001) and the
low frequency of glucose monitoring. Measuring glucose every 8 hours (OR= 3.583 ± 1.506-8.524,
p=0.004) and/or every 12 hours (OR=7.647 ± 0.704-79.231, p=0.0095) was associated with hyperglycemia.
The major factor perceived by nurses as a barrier to successful hyperglycemia management was
the lack of knowledge about appropriate insulin use (87.5%).

Conclusion:

Considerable mismanagement of hyperglycemia in diabetic non-critically ill patients exists;
indicating a compelling need for the development and implementation of protocol-driven insulin
order forms a comprehensive education plan on the appropriate use of insulin.
Characterization of Physical and Motor Disability at the Technical University of Manabí and Its Relationship with Resilience
Authors: Macías Tania Maritza Díaz , Meza Anicia Katherine Tarazona , Garcia Bibian Bibeca Bumbila , Bozada Madeleine Alexandra Tóala
Published: January 2018

The work aims to determine the characterization of physical and motor disability and its relation to resilience in the students of the Technical University of Manabí. The paper shows an analysis of physical motor disability in students and its impact on the level of resilience. The resilience analysis was addressed terms physical and mental state of the people, as well as the process of adapting to the problems and adversities of life. The results were shown in tables and graph on the analysis of the degree of physical-motor disability of the students as well as the application of the SV-RES test prepared by the researchers Saavedra & Villalta, 2008. Based on the evaluation of 12 dimensions, which they allow to verify the situation according to three scales: high, average and low. Finally, the conclusions were offered where the objective stated in the investigation was verified.
Cloning of acetyl-CoA acetyltransferase gene from Halomonas elongata BK-AG18 and in silico analysis of its gene product
Authors: Yuliastri Ni Putu , Ratnaningsih Enny , Hertadi Rukman
Published: January 2018

Polyhydroxybutyrate (PHB) is a biodegradable polymer that can be used as a substitute for petrochemical plastics. Bacteria accumulate PHB in their cells as carbon and energy reserves because of unbalanced growth conditions.  This study aimed to amplify phbA from the chromosomal DNA of Halomonas elongata BK-AG18, a PHB-producing bacterium that was previously isolated from the Bledug Kuwu mud crater of Central Java, Indonesia. The obtained phbA amplicon was 1176 bp. This fragment was cloned into a pGEM-T Easy cloning vector and used to transform Eschericia coli TOP10. The recombinant colonies were selected using blue-white screening, confirmed by size screening, reconfirmed by re-PCR, and sequenced. When putative phbA sequences were aligned with H. elongata DSM2581 chromosome using BLASTN, this sequence showed 99% identity. The deduced amino acid sequences of this clone showed 100% identity to PhbA of  H. elongata DSM2581, suggesting that the obtained cloned fragment is a  phbA  gene. The 3D structure predicted by I-TASSER showed that PhbA of H. elongata  BK-AG18 had a high similarity to the acetyl CoA acetyltransferase structure of  Ralstonia eutropha H16. PhbA of H. elongata BK-AG18 possesses three catalytic residues, namely Cys88, His348, and Cys378.
Konstant online og fantasien om ’individuel balance’ - Et psykoanalytisk perspektiv på arbejdsintensivering via mobilen
Authors: Villadsen Kaspar
Published: January 2018

Smartphones og andre mobile kommunikationsteknologier indføres med løfter om at give øget handlekraft og individuel frihed i arbejdslivet. Men et voksende forskningsfelt påviser, at indførelse af disse teknologier ledsages af øget netværksbaseret kontrol og selv-pålagt arbejdsintensivering. Artiklen leverer et overblik over og en diskussion af den spirende internationale forskning i betydningen af smartphones i nutidens arbejdsliv. Denne forskning påpeger generelt en modsætning mellem en diskurs om teknologiers påståede styrkelse af individuel autonomi og præstation på den ene side, og den reelle indrullering af teknologibrugere i nye former for kontrol og en usund arbejdskultur, der indebærer konstant ’opkobling’ på den anden. Artiklen foreslår med afsæt hos Žižek en alternativ vinkel på denne problematik, idet den præsenterer en række overvejelser over, hvordan medarbejderes frivillige omfavnelse af smartphones som arbejdsredskab kan begribes, når medarbejderne udtrykker fuld bevidsthed om teknologiens konkrete skadevirkninger på deres private liv.