bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Synthesis, Crystal Structure, and Spectrum Properties of a New Borate Ba4K2Zn5 (B3O6)3(B9O19) with Two Isolated Types of Blocks: 3[3Δ] and 3[2Δ + 1T] + 3Δ + 3[2Δ + 1T].
Authors: Chen Xuean , Chen Yanjun , Wu Long , Chang Xinan , Xiao Weiqiang
Published: March 2014

Single crystals of the new title compound are obtained from a melt of composition BaCO3/ZnO/H3BO3/K2CO3 /K2B4O7·4H2O/ Bi2O3 = 4:4:18:1:3:1 (Pt crucible, 750 °C, 7 d).
ChemInform Abstract: Synthesis, Structure, and Characterization of a New Rubidium Cadmium Borate: RbCdB3O6.
Authors: Jiao Anqing , Wu Hongping , Pan Shilie , Yu Hongwei , Yang Zhihua , Lei Chen
Published: March 2014

Single crystals of the new title compound are prepared by solid state reaction of Rb2CO3, CdO, and H3BO3 in a molar ratio of 4:1:6 (Pt crucible, 750 °C, 10 h).
ChemInform Abstract: The Hexaammine Copper(II) Fluoride Monohydrate [Cu(NH3)6][F(H2O)F]: Synthesis and Crystal Structure.
Authors: Woidy Patrick , Meng Weizhe , Kraus Florian
Published: March 2014

[Cu(NH3)6]F2·H2O is prepared by reaction of CuF2·2H2O in liq.
ChemInform Abstract: Sr2Au6Al3 and Eu2Au6Al3 — First Representatives of the Sr2Au6Zn3 Type with Aluminum Triangles.
Authors: Gerke Birgit , Poettgen Rainer
Published: March 2014

Sr2Au6Al3 (I) and Eu2Au6Al3 (II) are prepared by melting the elements in a molar ratio of 3:7.2:3 in a muffle furnace for (I) (sealed Ta tube in a silica tube, 1.
ChemInform Abstract: The Development of Highly Active Acyclic Chiral Hydrazides for Asymmetric Iminium Ion Organocatalysis.
Authors: Gould Eoin , Lebl Tomas , Slawin Alexandra M. Z. , Reid Mark , Davies Tony , Smith Andrew D.
Published: March 2014

Double asymmetric induction is employed as a tool to optimize pyrazolidinone derived organocatalysts for the asymmetric iminium ion catalyzed Diels—Alder reaction.
ChemInform Abstract: Chiral Olefin—Sulfoxide as Ligands for Rhodium‐Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to Unsaturated Esters.
Authors: Xue Feng , Wang Dongping , Li Xincheng , Wan Boshun
Published: March 2014

Sterically hindered aryl boronic acids, e.g. (IIf), and boronic acids bearing electron‐withdrawing substituents, e.g. (IIe), do not affect the stereoselectivity, however have a significant effect on the reactivity.
ChemInform Abstract: Nano Ceria Catalyzed Synthesis of Substituted Benzimidazole, Benzothiazole, and Benzoxazole in Aqueous Media.
Authors: Shelkar Radheshyam , Sarode Sachim , Nagarkar Jayashree
Published: March 2014

It is demonstrated that CeO2‐nanoparticles efficiently catalyze the condensation of 1,2‐phenylenediamine, 2‐aminothiophenol, or 2‐aminophenol with aldehydes to give the title compounds in high yields.
ChemInform Abstract: Substrate‐Directable Electron Transfer Reactions: Dramatic Rate Enhancement in the Chemoselective Reduction of Cyclic Esters Using SmI2—H2O: Mechanism, Scope, and Synthetic Utility.
Authors: Szostak Michal , Spain Malcolm , Choquette Kimberly A. , Flowers Robert A. II , Procter David J.
Published: March 2014

The presence of a suitably placed directing group dramatically accelerates the rate of the reduction of cyclic esters, such as (I), (III), (V), and (VII) with SmI2—H2O.
ChemInform Abstract: Ring Expansion of 3‐Oxetanone‐Derived Spirocycles: Facile Synthesis of Saturated Nitrogen Heterocycles.
Authors: Ruider Stefan A. , Mueller Steffen , Carreira Erick M.
Published: March 2014

The new efficient method for the catalytic ring expansion of oxetane derivatives leads to numerous oxazine, pyrazine, and thiazine derivatives which are difficult to access otherwise.
ChemInform Abstract: Catalytic Asymmetric Reduction of Prochiral Ketones with Chiral β‐Amino Alcohol N‐Boranes and the Corresponding Tris(oxazaborolidine)borazines.
Authors: Pinaka Afroditi , Dimotikali Dimitra , Chankvetadze Bezhan , Papadopoulos Kyriakos , Vougioukalakis Georgios C.
Published: March 2014

The catalytic activity of chiral monomeric and trimeric boron catalysts in the asymmetric reduction of prochiral ketones are evaluated.
ChemInform Abstract: Chemo‐, Regio‐, and Stereoselective Iron‐Catalyzed Hydroboration of Alkenes and Alkynes.
Authors: Greenhalgh Mark D. , Thomas Stephen P.
Published: March 2014

A facile method for the synthesis of alkyl‐ and vinyl boronic esters (III) and (V) showing good functional group tolerance is described using in situ activation of a bench‐stable Fe(II) pre‐catalyst and pinacolborane (II).
ChemInform Abstract: Rhodium‐Catalyzed Asymmetric Addition of Arylboronic Acids to β‐Nitroolefins: Formal Synthesis of (S)‐SKF 38393.
Authors: Huang Kung‐Chih , Gopula Balraj , Kuo Ting‐Shen , Chiang Chien‐Wei , Wu Ping‐Yu , Henschke Julian P. , Wu Hsyueh‐Liang
Published: March 2014

An efficient enantioselective addition of an array of arylboronic acids to various β‐nitrostyrenes catalyzed by a novel and reactive rhodium—diene catalyst is developed, providing β,β‐diarylnitroethanes.
ChemInform Abstract: Nickel‐Catalyzed Sonogashira Reactions of Non‐activated Secondary Alkyl Bromides and Iodides.
Authors: Yi Jun , Lu Xi , Sun Yan‐Yan , Xiao Bin , Liu Lei
Published: March 2014

This reaction tolerates a broad variety of functional groups.
ChemInform Abstract: Diastereoselective Methyl Orthoformate Alkylations of Chiral N‐Acylthiazolidinethiones Catalyzed by Nickel(II) Complexes.
Authors: Romo Juan Manuel , Galvez Erik , Nubiola Ignasi , Romea Pedro , Urpi Felix , Kindred Max
Published: March 2014

The reaction proceeds with complete diastereoselectivity.
ChemInform Abstract: A Convenient Metal‐Free Reagent for the Generation and Capture of Trifluoromethanethiol.
Authors: Li Shi‐Guang , Zard Samir Z.
Published: March 2014

Both newly synthesized reagents (III) and (IV) are proved to be valuable for introducing the CF3 or CF3S‐ motifs trough radical and ionic mechanisms, respectively.
ChemInform Abstract: Synthesis of Cyclobutanones via Gold‐Catalyzed Oxidative Rearrangement of Homopropargylic Ethers.
Authors: Xu Mei , Ren Tian‐Tian , Wang Kai‐Bing , Li Chuan‐Ying
Published: March 2014

A novel approach to cis‐disubstituted cyclobutanones from homopropargylic ethers with an electron rich alkenyl or aryl substituent is developed.
ChemInform Abstract: First Tandem Asymmetric Conjugate Addition of Alkenyl Nucleophiles and Silyl Trapping of the Intermediate Enolates.
Authors: Westmeier Johannes , Pfaff Christopher , Siewert Juergen , von Zezschwitz Paultheo
Published: March 2014

The asymmetric Rh‐catalyzed addition of alkenylzirconocenes is described.
ChemInform Abstract: Facile Method for the Synthesis of Oseltamivir Phosphate.
Authors: Kalashnikov A. I. , Sysolyatin S. V. , Sakovich G. V. , Sonina E. G. , Shchurova I. A.
Published: March 2014

Oseltamivir phosphate (I) is synthesized in a short ten‐step route from (‐)‐shikimic acid with a total yield of 27%.
ChemInform Abstract: Palladium‐Catalyzed Intramolecular ipso‐Friedel—Crafts Allylic Alkylation of Phenols via Arylative Activation of Allenes.
Authors: Nemoto Tetsuhiro , Nozaki Tomoyuki , Yoshida Mariko , Hamada Yasumasa
Published: March 2014

A novel Pd‐catalyzed Heck insertion to an allene followed by an intramolecular ipso‐Friedel—Crafts allylic alkylation cascade is described to convert functionalized phenols (I) and (IV) to spiro[4.5]cyclohexadienones.
ChemInform Abstract: A Phosphite‐Pyridine/Iridium Complex Library as Highly Selective Catalysts for the Hydrogenation of Minimally Functionalized Olefins.
Authors: Mazuela Javier , Pamies Oscar , Dieguez Montserrat
Published: March 2014

The first successful application of phosphite‐pyridine ligands in the Ir‐catalyzed asymmetric hydrogenation of di‐ and trisubstituted olefins is developed.
ChemInform Abstract: CuCl‐Catalyzed Ring‐Opening Isomerization of gem‐Chlorofluorocyclopropanes with the Formation of Chlorofluoroalkenes and Chlorofluoroalkadienes.
Authors: Novikov M. A. , Volchkov N. V. , Lipkind M. B. , Nefedov O. M.
Published: March 2014

Title reactions are easily effected in the presence of CuCl with phenyl‐, alkyl‐, vinyl‐, and cyclopropyl‐substituted cyclopropanes.
ChemInform Abstract: Silver‐Catalyzed Hydrogenation of Aldehydes in Water.
Authors: Jia Zhenhua , Zhou Feng , Liu Mingxin , Li Xingshu , Chan Albert S. C. , Li Chao‐Jun
Published: March 2014

An unprecedented catalytic activity of silver complexes is discovered to allow the catalytic hydrogenation of aldehydes to alcohols in water as the solvent.
ChemInform Abstract: Enantioselective Morita—Baylis—Hillman Reaction Catalyzed by a Chiral Phosphine Oxide.
Authors: Kotani Shunsuke , Ito Masaya , Nozaki Hirono , Sugiura Masaharu , Ogasawara Masamichi , Nakajima Makoto
Published: March 2014

A hypervalent silicon complex generated from a chiral phosphine oxide catalyst and SiCl4 reacts with vinyl ketones (I) to give the corresponding γ‐chloro silyl enol ether intermediates.
ChemInform Abstract: Ruthenium‐Catalyzed C—H Functionalization of Arylpyrazoles: Regioselective Acylation with Acid Chlorides.
Authors: Liu Po Man , Frost Christopher G.
Published: March 2014

A ruthenium‐catalyzed C—H non‐Friedel‐Crafts acylation of arylpyrazoles with a variety of acyl chlorides is described.
ChemInform Abstract: Catalytic Thiomethylation of Carboxylic Acid Hydrazides.
Authors: Khairullina R. R. , Akmanov B. F. , Kunakova R. V. , Ibragimov A. G. , Dzhemilev U. M.
Published: March 2014

N′,N′‐bis(sulfanylmethyl)carbohydrazides and N‐substituted dithiazepanes, dithiazocanes, and dithiazonanes are efficiently obtained by thiomethylation of carboxylic acid hydrazides mediated by transition metal‐based and rare earth‐based catalysts.
ChemInform Abstract: Reactivity Change of Cyclobutanols Towards Isocyanates: Rhodium Favors C‐Carbamoylation over O‐Carbamoylation.
Authors: Ishida Naoki , Nakanishi Yuuta , Murakami Masahiro
Published: March 2014

In the presence of a rhodium catalyst, the pathway of the reaction of cyclobutanols and isocyanates is directed to C‐carbamoylation through a ring‐opening process.
ChemInform Abstract: Catalytic Cyanation of Carbon—Carbon Triple Bonds Through a Three‐Component Cross‐Coupling Reaction under Nickel Catalysis.
Authors: Yang Xiaofei , Arai Shigeru , Nishida Atsushi
Published: March 2014

A nickel(0) complex effectively catalyzes a sequential coupling reaction between allenes, alkynes and hydrogen cyanide generated from acetone cyanohydrin in a highly regio‐ and stereoselective fashion.
ChemInform Abstract: Rhodium‐Catalyzed Denitrogenative [2,3] Sigmatropic Rearrangement: An Efficient Entry to Sulfur‐Containing Quaternary Centers.
Authors: Yadagiri Dongari , Anbarasan Pazhamalai
Published: March 2014

A convenient protocol is developed for the denitrogenative [2,3] sigmatropic rearrangement of triazoles with allyl sulfides and benzylphenyl sulfide.
ChemInform Abstract: Copper‐Catalyzed Synthesis of α‐Thioaryl Carbonyl Compounds Through S—S and C—C Bond Cleavage.
Authors: Zou Liang‐Hua , Priebbenow Daniel L. , Wang Long , Mottweiler Jakob , Bolm Carsten
Published: March 2014

Copper‐catalyzed reaction of β‐dicarbonyl compounds with diaryl disulfides allows the synthesis of α‐thioarylketones, esters, and amides.
ChemInform Abstract: Platinum‐Catalyzed C—H Arylation of Simple Arenes.
Authors: Wagner Anna M. , Hickman Amanda J. , Sanford Melanie S.
Published: March 2014

The first example of a Pt‐catalyzed direct C—H arylation of simple arenes (I), (IV), and (VI) with diaryliodonium salts (II) is described.
ChemInform Abstract: Influence of 1,3‐Difluorobenzene Substituents for Palladium‐Catalyzed Direct Arylations.
Authors: Yan Tao , Bheeter Charles Beromeo , Doucet Henri
Published: March 2014

A very regioselective C2‐arylation of 1,3‐difluorobenzene derivatives with a variety of aryl bromides is presented.
ChemInform Abstract: Hydrido‐Cobalt Catalyst as a Selective Tool for the Dimerization of Arylacetylenes: Scope and Theoretical Studies.
Authors: Ventre Sandrine , Derat Etienne , Amatore Muriel , Aubert Corinne , Petit Marc
Published: March 2014

The dimerization of arylacetylenes in the presence of the hydrido‐cobalt complex proceeds with high regio‐ and stereoselectivity to produce (E)‐1,4‐enynes in excellent yield.
ChemInform Abstract: Silver‐Promoted Benzannulations of Siloxyalkynes with Pyridinium and Isoquinolinium Salts.
Authors: Cabrera‐Pardo Jaime R. , Chai David I. , Kozmin Sergey A.
Published: March 2014

The title reaction proceeds under mild conditions via a formal inverse‐electron demand Diels—Alder reaction, followed by fragmentation of the initially formed bicyclic intermediates to produce naphthol and phenol derivatives.
ChemInform Abstract: Formation of Dihydronaphthalenes via Organocatalytic Enantioselective Michael—Aldol Cascade Reactions with Arylalkanes.
Authors: Li Xiangmin , Wang Sinan , Li Tengfei , Li Jian , Li Hao , Wang Wei
Published: March 2014

A new organocatalytic highly enantioselective nucleophilic carbon initiated Michael—aldol cascade reaction for one‐pot construction of chiral dihydronaphthalenes is developed.
ChemInform Abstract: Unusual Reaction of Diazomethane with Stereoisomeric 3‐(Benzylcarbamoyl) ‐5,6,7,8‐tetrachloro‐1,4‐methano‐1,2,3,4‐tetrahydronaphthalene‐2‐carboxy lic Acids.
Authors: Ismailov S. A.
Published: March 2014

Attempts to convert cyclic amido acid (I) and its diastereomer (III) into corresponding amido esters by treatment with diazomethane result in the unexpected selective formation of corresponding dicarboxylic acid amides.
ChemInform Abstract: Carbene Transfer — A New Pathway for Propargylic Esters in Gold Catalysis.
Authors: Lauterbach Tobias , Gatzweiler Sabrina , Noesel Pascal , Rudolph Matthias , Rominger Frank , Hashmi A. Stephen K.
Published: March 2014

Treatment of bisalkynyl substrates (I) and (III) with catalytic amounts of AuCl results in the formation of vinyl‐substituted β‐naphthol derivatives.
ChemInform Abstract: Efficient Synthesis of Functionalized 1‐Oxo‐1‐phenyl‐2‐acetic Acids Through Ru(II)‐Catalyzed Transfer Hydrogenation.
Authors: Wang Xiaowei , Yan Yunnan , Gong Binwei , Tang Xiaobo , Li Qiu , Meng Yanqin , Xu H. Eric , Yi Wei
Published: March 2014

A new and efficient method for the synthesis of indanylacetic acid via chemoselective transfer hydrogenation of corresponding oxoindanylideneacetic acids (I) is developed.
ChemInform Abstract: Palladacycle‐Catalyzed Methylenecyclopropanation of Bicyclic Alkenes with Propiolates.
Authors: Mo Dong‐Liang , Yuan Teng , Ding Chang‐Hua , Dai Li‐Xin , Hou Xue‐Long
Published: March 2014

The title reaction is only applicable to terminal propiolates.
ChemInform Abstract: Exploitation of Dual Character of CN Moiety in the Synthesis of Uniquely Decorated 3H‐Pyrroles: A Rare Observation.
Authors: Das Paramita , Ray Suman , Mukhopadhyay Chhanda
Published: March 2014

The approach to 3H‐pyrroles presented herein offers an unprecedented coupling which leads to the construction of the nitrogen containing ring without starting from any amine moiety.
ChemInform Abstract: Cu(II)‐Catalyzed Highly Regio‐ and Stereoselective Construction of C—C Double Bonds: An Efficient Method for the Ketonization—Olefination of Indoles.
Authors: Bao Yun‐Hong , Zhu Jia‐Yi , Qin Wen‐Bing , Kong Yu‐Bo , Chen Zheng‐Wang , Tang Shao‐Bin , Liu Liang‐Xian
Published: March 2014

A novel method for the cross‐coupling of indoles (I) with β‐keto esters (II), (V), and (VII) using TEMPO/CuSO4 in air as oxidant is described.
ChemInform Abstract: Regiospecific Benzylation of Tryptophan and Derivatives Catalyzed by a Fungal Dimethylallyl Transferase.
Authors: Liebhold Mike , Li Shu‐Ming
Published: March 2014

The acceptance of benzyl diphosphate (II) as an alkyl donor by the fungal dimethylallyl transferase FgaPT2 and the regiospecific enzymatic benzylation of tryptophan and analogues are studied.
ChemInform Abstract: (R/S)‐BINOL‐α‐Phosphoryloxy Enecarbamate‐Mediated and (R/S)‐Titanium(IV) BINOLates‐Catalyzed Enantioselective Intramolecular Heck/Aza‐Diels—Alder Cycloaddition (IHADA): An Expedient Methodology.
Authors: Khan Imran A. , Saxena Anil K.
Published: March 2014

The conversion of o‐vinyl substituted N‐Boc‐N‐acetyl anilines to enecarbamates and subsequent Diels—Alder reaction in the presence of enantiopure BINOL as chiral source is developed.
ChemInform Abstract: Reaction of 3‐(Alken‐1‐yl)‐4,5‐dihydro‐3H‐pyrazoles with Sodium Nitrite in Acetic Acid.
Authors: Yakovlev K. V. , Khanova M. D. , Petrov D. V. , Kuleshov S. P. , Dokichev V. A.
Published: March 2014

Nitrosation of 3‐vinyldihydropyrazole (I) affords the 1‐nitrosopyrazole (II), whereas 3‐isopropenyldihydropyrazole (III) gives unexpectedly the side‐chain nitrosated derivative (IV).
ChemInform Abstract: A Sustainable Route Towards Imidazolium Building Blocks Based on Biomass Molecules.
Authors: Esposito Davide , Kirchhecker Sarah , Antonietti Markus
Published: March 2014

A simple one‐pot protocol for the synthesis of bifunctional imidazolium compounds via three component reaction of amino acids or aliphatic amines with pyruvaldehyde and formaldehyde is developed.
ChemInform Abstract: Easy Conjugations Between Molecules via Copper‐Catalyzed Reactions of ortho‐Aromatic Diamines with Ketones.
Authors: Lu Juyou , Yang Haijun , Jin Yunhe , Jiang Yuyang , Fu Hua
Published: March 2014

A highly efficient method for the synthesis of benzo[d]imidazole derivatives (III) (34 examples) via Cu‐catalyzed reaction of o‐phenylenediamines with ketones is developed.
ChemInform Abstract: Synthesis of Novel 1,3‐Oxazole Derivatives with Insect Growth‐Inhibiting Activities.
Authors: Guo Peng , Huang Jun‐Hai , Huang Qing‐Chun , Qian Xu‐Hong
Published: March 2014

A series of novel asymmetrically disubstituted oxazole derivatives (IV) (20 examples) are synthesized and evaluated for their armyworm growth regulating activities.
ChemInform Abstract: Condensation of Vilsmeier Salts, Derived from Tetraalkylureas, with Amidoximes: A Novel Approach to Access N,N‐Dialkyl‐1,2,4‐oxadiazol‐5‐amines.
Authors: Su Dongshan , Duan Haifeng , Wei Zhonglin , Cao Jungang , Liang Dapeng , Lin Yingjie
Published: March 2014

The condensation of Vilsmeier salts and amidoximes proceeds under mild conditions to give oxadiazol derivatives.
ChemInform Abstract: An Improved Synthesis and Some Reactions of Diethyl 4‐Oxo‐4H‐pyran‐2,5‐dicarboxylate.
Authors: Obydennov Dmitrii L. , Roeschenthaler Gerd‐Volker , Sosnovskikh Vyacheslav Ya.
Published: March 2014

Condensation of 2‐(dimethylamino)methylene‐3‐oxobutanoate with diethyl oxalate in the presence of NaH and following HCl‐promoted cyclization offers an improved synthesis of 4‐oxo‐4H‐pyran‐2,5‐dicarboxylate (IV).
ChemInform Abstract: A Practical Access to Highly Enantiomerically Pure Flavanones by Catalytic Asymmetric Transfer Hydrogenation.
Authors: Metz Peter , et al. et al.
Published: March 2014

The asymmetric transfer hydrogenation of racemic flavones in the presence of a rhodium catalyst is developed.
ChemInform Abstract: A Selective Synthesis of 4‐Bromoisoquinoline and 4‐Bromoisoquinolone.
Authors: Zhang Hong‐Ping , Li Hong‐Yan , Xiao Hong‐Fang
Published: March 2014

An efficient method for the selective synthesis of 4‐bromoisoquinoline and ‐isoquinolone derivatives via Pd‐catalyzed cyclization of 2‐alkynylbenzyl azides is developed.
ChemInform Abstract: A Concise Synthesis of Indoloquinoline Skeletons Applying Two Consecutive Pd‐Catalyzed Reactions.
Authors: Boganyi Borbala , Kaman Judit
Published: March 2014

The synthesis of indoloquinolines from bromo‐iodoquinolines by following a two‐step strategy based on a Buchwald—Hartwig amination as a first step followed by an intramolecular Heck‐type reaction to execute the ring closure is described.
ChemInform Abstract: Two New Indole Derivatives as Anion Receptors for Detecting Fluoride Ion.
Authors: Liu Xiu‐Ming , Zhao Qiang , Li Yue , Song Wei‐Chao , Li Ya‐Ping , Chang Ze , Bu Xian‐He
Published: March 2014

The two new indole derivatives (III) and (IV) display highly selective response to fluoride anions in aqueous DMSO and pure DMSO medium with remarkable color and fluorescence changes.
ChemInform Abstract: Rhodium‐Catalyzed Oxidative Annulation of Sulfoximines and Alkynes as an Approach to 1,2‐Benzothiazines.
Authors: Dong Wanrong , Wang Long , Parthasarathy Kanniyappan , Pan Fangfang , Bolm Carsten
Published: March 2014

Rh‐catalyzed oxidative cyclocondensation of NH‐sulfoximines and internal alkynes provides an efficient synthesis of 1,2‐benzothiazines.
ChemInform Abstract: An Expedient Route to Dihydrothiazines, a Virtually Unknown Class of Heterocycles.
Authors: Quiclet‐Sire Beatrice , Zard Samir Z.
Published: March 2014

Upon heating in diphenyl ether, S‐(4‐oximinoalkyl)xanthates with a secondary isopropyl or isobutyl group on the oxygen undergo a Chugaev elimination followed by ring closure onto the oxime giving dihydrothiazines, a virtually unknown class of heterocycles.
ChemInform Abstract: Amine‐Free Approach Toward N‐Toluenesulfonyl Amidine Construction: A Phosphite‐Mediated Beckmann‐Like Coupling of Oximes and p‐Toluenesulfonyl Azide.
Authors: Fleury Lauren M. , Wilson Erin E. , Vogt Monika , Fan Tiffany J. , Oliver Allen G. , Ashfeld Brandon L.
Published: March 2014

The reaction of oximes (I) with the chlorophosphite (II) and tosyl azide is examined resulting in the formation of N‐tosyl amidines through a Beckmann‐type process.
ChemInform Abstract: Synthesis of Tetrasubstituted α‐Aminophosphonic Acid Derivatives from Trisubstituted α‐Aminophosphonates.
Authors: Vicario Javier , Ortiz Pablo , Palacios Francisco
Published: March 2014

Addition reaction of organometallic reagents to tertiary α‐iminophosphonates offers an efficient strategy for the preparation of quaternary α‐aminophosphonates.
ChemInform Abstract: Synthesis of Trisubstituted Alkenylstannanes Through Copper‐Catalyzed Three‐Component Coupling of Alkylboranes, Alkynoates, and Tributyltin Methoxide.
Authors: Wakamatsu Takamichi , Nagao Kazunori , Ohmiya Hirohisa , Sawamura Masaya
Published: March 2014

The reaction of monosubstituted ethenes with (9‐BBN)2 and subsequent Cu‐catalyzed coupling of the resulting alkylborane with acetylenic esters and Bu3SnOMe offers a stereoselective synthesis of highly functionalized vinyl stannanes.
ChemInform Abstract: Benzothiadiazole‐Based Dyes that Emit Red Light in Solution, Solid and Liquid State.
Authors: Ishi‐i Tsutomu , Sakai Miki , Shinoda Chihiro
Published: March 2014

The preparation and red‐light‐emitting behavior of benzothiadiazole‐tris(alkyloxy)phenylene dyes (I) are reported.
ChemInform Abstract: Two New Cytotoxic Sesquiterpenoids from Solanum lyratum.
Authors: Li Gui‐Sheng , Yao Fang , Zhang Lei , Yue Xi‐Dian , Dai Sheng‐Jun
Published: March 2014

In vitro, both eudesmane‐type sesquiterpenoids (I) (named solajiangxins F and G), show significant cytotoxic activity against selected cancer cells such as P‐388, HONE‐1, and HT‐29.
ChemInform Abstract: Anticancer Evaluation of Carboxamides of Furano‐Sesquiterpene Carboxylic Acids from the Soft Coral Sinularia kavarattiensis.
Authors: Venkateswarlu Yenamandra , et al. et al.
Published: March 2014

New furano‐sesquiterpene carboxylic acid derivatives (I) are isolated and transformed into new amide derivatives (II).
ChemInform Abstract: Pahangensin A and B, Two New Antibacterial Diterpenes from the Rhizomes of Alpinia pahangensis Ridley
Authors: Sivasothy Yasodha , Ibrahim Halijah , Paliany Audra Shaleena , Alias Siti Aisyah , Awang Khalijah
Published: March 2014

isolation, structure elucidation and antibacterial activity
ChemInform Abstract: Nickel‐Catalyzed Arylation, Alkenylation, and Alkynylation of Unprotected Thioglycosides at Room Temperature.
Authors: Brachet Etienne , Brion Jean‐Daniel , Alami Mouad , Messaoudi Samir
Published: March 2014

A catalyst system based on in situ generated Ni(0) is shown to efficiently promote the coupling reaction of unprotected thiosaccharides with alkenyl, alkynyl, and aryl halides.
ChemInform Abstract: Organocatalyzed Direct Glycosylation of Unprotected and Unactivated Carbohydrates.
Authors: Schmalisch Sebastian , Mahrwald Rainer
Published: March 2014

An organocatalyzed direct glycosylation of unprotected and unactivated carbohydrates is reported.
ChemInform Abstract: Divergent Total Syntheses of (‐)‐Lycopladine D, (+)‐Fawcetttidine, and (+)‐Lycoposerramine Q.
Authors: Zeng Chen , Zheng Changwu , Zhao Jingyun , Zhao Gang
Published: March 2014

Enantioselective total syntheses of (+)‐fawcettidine (I) and (+)‐lycoposerramine Q (II) as well as the first total synthesis of (‐)‐lycopladine D (III) from a common intermediate is accomplished by a divergent path (not shown).
ChemInform Abstract: Formal Synthesis of (+)‐Tashiromine and Study Toward the Total Synthesis of (+)‐Stemoamide.
Authors: Chen Yue‐Jie , Bao Rui‐Yang , Zhang Xiao‐Dong , Tang Ye‐Feng
Published: March 2014

Tashiromine (IV) is obtained by employing an intramolecular asymmetric Mannich‐Type reaction as the key step.
ChemInform Abstract: Total Synthesis of Thaxtomin A and Its Stereoisomers and Findings of Their Biological Activities.
Authors: Wang Xin , et al. et al.
Published: March 2014

The first and facile total synthesis of thaxtomin A (I) and its stereoisomers (not shown) is presented.
ChemInform Abstract: Nivetetracyclates A and B: Novel Compounds Isolated from Streptomyces niveus.
Authors: Song Fuhang , et al. et al.
Published: March 2014

A high‐throughput screening of a microbial natural product library leads to the discovery of two novel compounds named nivetetracyclates A (I) and B (II), which are produced by Streptomyces niveus designated as LS2151.
ChemInform Abstract: Hidden Order. Does a New Theory Solve the Decades‐old Puzzle of Phase Transition in URu2Si2?
Authors: Vojta Matthias
Published: March 2014

Review: 15 refs.
ChemInform Abstract: Artificial Carbonate Nanocrystals and Layered Structural Nanocomposites Inspired by Nacre: Synthesis, Fabrication and Applications
Authors: Yao Hong‐Bin , Ge Jin , Mao Li‐Bo , Yan You‐Xian , Yu Shu‐Hong
Published: March 2014

Review: 199 refs.
ChemInform Abstract: Advance in Solid‐State Purification Technology for Metals
Authors: Tian Feng , Li Guoling , Li Li , Wang Zhiqiang , Yan Shihong , Li Xingguo
Published: March 2014

Review: 97 refs.
ChemInform Abstract: Sensitive and Selective Gold Nanomaterials Based Optical Probes
Authors: Ho Lin‐Chen , Wang Chia‐Wei , Roy Prathik , Chang Huan‐Tsung
Published: March 2014

Review: 111 refs.
ChemInform Abstract: Advances in Thermochromic Vanadium Dioxide Films
Authors: Warwick Michael E. A. , Binions Russell
Published: March 2014

Review: 182 refs.
ChemInform Abstract: Chromium‐ and Manganese‐Containing Carbonyl Chalcogenide Clusters: Syntheses, Reactivities, and Special Properties
Authors: Shieh Minghuey , Lin Chien‐Nan
Published: March 2014

Review: [23 refs.
ChemInform Abstract: Fascinating Chemistry or Frustrating Unpredictability: Observations in Crystal Engineering of Metal‐Organic Frameworks
Authors: Goesten Maarten G. , Kapteijn Freek , Gascon Jorge
Published: March 2014

Review: 87 refs.
ChemInform Abstract: Trends in the Chemistry of Mono‐ to Multimetal π‐Arene Complexes of Chromium and Manganese
Authors: Bezuidenhout Daniela I. , van der Westhuizen Belinda , van Jaarsveld Nina A. , Lotz Simon
Published: March 2014

Review: 105 refs.
ChemInform Abstract: Synthesis, Chemical and Biological Properties of Aziridine‐1‐carbaldehyde Oximes
Authors: Nikitjuka A. , Jirgensons A.
Published: March 2014

Review: 23 refs.
ChemInform Abstract: Synthesis of Macromonocyclic Hydroxamic Acids
Authors: Borovika D. , Bertrand P. , Trapencieris P.
Published: March 2014

Review: 56 refs.
ChemInform Abstract: 1,3,4‐Oxadiazole
Authors: Dave S. B. , Godhani P. , Ushir Y.
Published: March 2014

Review: use of oxadiazole derivatives in in various field like polymer industry and, ost notably, medicinal chemistry; 70 refs.
ChemInform Abstract: Synthesis and Biological Evaluation of 1,3‐Thiazines
Authors: Simerpreet Simerpreet , Damanjit Cannoo Singh
Published: March 2014

Review: 43 refs.
ChemInform Abstract: Organophosphorus Catalysis to Bypass Phosphine Oxide Waste
Authors: van Kalkeren Henri A. , van Delft Floris L. , Rutjes Floris P. J. T.
Published: March 2014

Review: 104 refs.
ChemInform Abstract: Recent Advances in the Catalytic Syntheses of Allenes: A Critical Assessment
Authors: Neff Robynne K. , Frantz Doug E.
Published: March 2014

Review: 57 refs.
ChemInform Abstract: Aquasomes: A Review
Authors: Sirikonda Ajay Kumar , Kumar B. Vijay , Soma Sekhar A. , Gopi M. , Babu H. Seshu , Rao G. Subba
Published: March 2014

Review: 14 refs.
ChemInform Abstract: Carbon‐Supported Palladium and Ruthenium Nanoparticles: Application as Catalysts in Alcohol Oxidation, Cross‐Coupling and Hydrogenation Reactions
Authors: Garcia‐Suarez Eduardo J. , Lara Patricia , Garcia Ana B. , Philippot Karine
Published: March 2014

Review: 92 refs.
ChemInform Abstract: Marine Natural Products
Authors: Hill Robert A.
Published: March 2014

Review: selection of the literature on marine natural products published in 2012; 108 efs.
ChemInform Abstract: Review on the Recent Progress in Low Band Gap Conjugated Polymers for Bulk Hetero‐Junction Polymer Solar Cells
Authors: Jhuo Hong‐Jyun , Yeh Po‐Nan , Liao Sih‐Hao , Li Yi‐Lun , Cheng Yu‐Shan , Chen Show‐An
Published: March 2014

Review: 62 refs.
ChemInform Abstract: Environmental Recovery by Magnetic Nanocomposites Based on Castor Oil
Authors: Souza Fernando Gomes Jr. , Oliveira Geiza Esperandio , Lopes Magnovaldo Carvalho
Published: March 2014

Review: 22 refs.
ChemInform Abstract: Prediction of Different Thermodynamic Properties for Systems of Alcohols and Sulfate‐Based Anion Ionic Liquids Using Modified UNIFAC
Authors: Hector Torben , Uhlig Lisa , Gmehling Juergen
Published: March 2014

Review: 13 refs.
ChemInform Abstract: Shake‐Rattle‐and‐Roll: A Model of Dynamic Structural Disorder in Supported Nanoscale Catalysts
Authors: Rehr J. J. , Vila F. D.
Published: March 2014

Review: 24 refs.
ChemInform Abstract: Solid‐State NMR of Nanomachines Involved in Photosynthetic Energy Conversion
Authors: Alia A. , Buda Francesco , de Groot Huub J. M. , Matysik Joerg
Published: March 2014

Review: 78 refs.
Neural organization of the second optic neuropil, the medulla, in the highly visual semiterrestrial crab Neohelice granulata
Authors: Sztarker Julieta , Tomsic Daniel
Published: March 2014

Crustaceans are widely distributed and inhabit very different niches. Many of them are highly visual animals. Nevertheless, the neural composition of crustacean optic neuropils deeper than the lamina is mostly unknown. In particular, semiterrestrial crabs possess a highly developed visual system and display conspicuous visually guided behaviors. A previous study shows that the first optic neuropil, the lamina of the crab Neohelice granulata, possesses a surprisingly high number of elements in each cartridge. Here, we present a comprehensive description of individual elements composing the medulla of that same species. Using Golgi impregnation, we characterized a wide variety of cells. Only considering the class of transmedullary neurons, we describe over 50 different morphologies including small‐ and large‐field units. Among others, we describe a type of centrifugal neuron hitherto not identified in other crustaceans or insects that probably feeds back information to every cartridge in the medulla. The possible functional role of such centrifugal elements is discussed in connection with the physiological and behavioral information on visual processing available for this crab. Taken together, the results reveal a very dense and complex neuropil in which several channels of information processing would be acting in parallel. We further examine our results considering the similarities and differences found between the layered organization and components of this crustacean medulla and the medullae of insects. J. Comp. Neurol. 522:3177–3193, 2014. © 2014 Wiley Periodicals, Inc.
Evidence that the central canal lining of the spinal cord contributes to oligodendrogenesis during postnatal development and adulthood in intact rats
Authors: Ševc Juraj , Matiašová Anna , Kútna Viera , Daxnerová Zuzana
Published: March 2014

Two waves of oligodendrogenesis in the ventricular zone of the spinal cord (SC‐VZ) during rat development, which take place between embryonic days 14 and 18 (E14–E18) and E20–E21, have been described. In the VZ of the brain, unlike the SC‐VZ, a third wave of oligodendrogenesis occurs during the first weeks of postnatal development. Using immunofluorescence staining of intact rat SC tissue, we noticed the presence of small numbers of Olig2+/Sox‐10+ cells inside the lining of the central canal (CC) during postnatal development and adulthood. Olig2+/Sox‐10+ cells appeared inside the lining of the CC shortly after birth, and their number reached a maximum of approximately 0.65 ± 0.14 cell/40‐μm section during the second postnatal week. After the latter development, the number of Olig2+/Sox‐10+ cells decreased to 0.21 ± 0.07 (P36) and 0.18 ± 0.1 cell/section (P120). At P21, Olig2+/Sox‐10+ cells inside the CC lining started to express other oligodendroglial markers such as CNPase, RIP, and APC. Olig2+/Sox‐10+ cells usually did not proliferate inside the CC lining and were only rarely found to be immunoreactive against oligodendrocyte progenitor markers such as NG2 or PDGFRα. Using 5‐bromo‐2‐deoxyuridine administration at P2, P11, P22, or P120–P125, we revealed that these cells arose in the CC lining during postnatal development and adulthood. Our findings confirmed that the CC lining is the source of a small number of cells with an oligodendroglial phenotype during postnatal development and adulthood in the SC of intact rats. J. Comp. Neurol. 522:3194–3207, 2014. © 2014 Wiley Periodicals, Inc.
HUBzero and Pegasus: integrating scientific workflows into science gateways
Authors: McLennan Michael , Clark Steven , Deelman Ewa , Rynge Mats , Vahi Karan , McKenna Frank , Kearney Derrick , Song Carol
Published: March 2014

In this paper, we described the benefits and the challenges of integrating existing scientific workflow technologies into science gateways. Scientific workflow managers are powerful tools for handling large computational tasks. Domain scientists find it difficult to create new workflows, so many tasks that could benefit from workflow automation are often avoided or performed by hand. Two technologies have come together to bring the benefits of workflow to the masses. The Pegasus Workflow Management System can manage workflows comprised of millions of tasks, all the while recording data about the execution and intermediate results so that the provenance of the final result is clear. The HUBzero platform for scientific collaboration provides a venue for building and delivering tools to researchers and educators. With the press of a button, these tools can launch Pegasus workflows on national computing infrastructures and bring results back for plotting and visualization. As a result, the combination of Pegasus and HUBzero is bringing high‐throughput computing to a much wider audience. Copyright © 2014 John Wiley & Sons, Ltd.
A new flow cytometric method for differential cell counting in ascitic fluid
Authors: van de Geijn Gert‐Jan M. , van Gent Marc , van Pul‐Bom Natasja , Beunis Marlène H. , van Tilburg Antonie J. P. , Njo Tjin L.
Published: March 2014

Background

Cell counts in bodyfluids such as ascitic fluid can be difficult to perform and report rapidly. The current gold standard for cell counting in body fluids is a suitable automated cell counter or a manual counting chamber, combined with differential counting on a cytospin. This technique has several disadvantages, so we designed a new flow cytometric test for cell counting in ascites. We compared this with an automatic cell counter (LH750, Beckman Coulter) and manual counting of cytospins.

Methods

Ascitic samples (n = 53) from 38 patients were studied. Polymorphonuclear neutrophils (PMN), lymphocytes, eosinophils, and macrophages were defined by flow cytometry. We compared this with our reference method: the absolute cell concentration calculated from the leukocyte concentration of the LH750 combined with a differential cell count performed manually on a cytospin.

Results

The outcomes of validation experiments (linearity, reproducibility, and detection limit) of the flow cytometric assay prove it is well suited for cell counting in ascitic fluid.

Conclusions

Based on analytical performance, flow cytometry is suited for cell counting in ascitic fluid. An ascitic fluid cell count is frequently ordered to detect spontaneous bacterial peritonitis (SBP). If the PMN count is ≥250 cells/mm3, SBP is highly suspected. Using our reference method, we calculated the sensitivities and specificities to detect ≥250 PMN cells/mm3for the LH750 (100% and 65%, respectively) and flow cytometric assay (100%, 100%). As flow cytometry is easier and faster we recommend this method for rapid cell counting in ascitic fluid. © 2014 International Clinical Cytometry Society
Alterations of lipid profile are a risk factor for venous thromboembolism and thrombotic complications
Authors: García‐Raso Aránzazu , Ene Gabriela Simona , Sillero Pilar Llamas
Published: March 2014

We studied a group of patients with thromboembolic disease, demographic data, thrombotic and classical cardiovascular risk factors, and thrombotic complications were collected. Lipid profile including total cholesterol, HDL cholesterol, LDL cholesterol, and triglycerides was established for all patients. Three hundred and thirty‐nine patients and 295 controls were included in the study. The mean age of both groups was 53.3 (±16.4) years for patients and 57.0 (±17.4) for controls (p = 0.006). Patient and control groups were composed of 53.4% (n = 181) and 52.2% (n = 154) of men, respectively (p = 0.765). LDL‐C > 180 mg/dL and TC > 220 mg/dL were associated with an increased risk of venous thromboembolism (VTE; OR: 7.76, 95% CI: 2.97–26.65, p < 0.0001 and OR: 2.22, 95%CI: 1.61–3.075, p < 0.0001, respectively). We found a statistically significant association between HDL‐C < 35 mg/dL (OR: 2.42, 95% CI: 1.15–5.16, p = 0.02) and LDL‐C > 180 mg/dL (OR: 1.93, 95% CI: 1.03–3.58, p = 0.04) with recurrent events. We found a significant association between HDL‐C < 35 mg/dL (OR: 2.35, 95%CI: 1.08–5.00, p = 0.031) and LDL‐C > 180 mg/dL (OR: 2.56, 95%CI: 1.34–4.83, p = 0.004) with PTS. Our study confirmed the association between dyslipidemia and VTE. In addition, alterations in the lipid profile were also related to a higher prevalence of thrombotic complications.

Practical applications: A deeper understanding of the risk factors associated with VTE and its major complications, recurrence and post‐thrombotic syndrome, allow us to identify earlier and more effectively those individuals with an increased risk of thrombosis, and therefore apply appropriate therapeutic and prophylactic measures in certain thrombotic risk situations.
LPS and IL‐1 differentially activate mouse and human astrocytes: Role of CD14
Authors: Tarassishin Leonid , Suh Hyeon‐Sook , Lee Sunhee C.
Published: March 2014

Treatment of cultures with toll‐like receptor (TLR) ligands or cytokines has become a popular approach to investigate astrocyte neuroinflammatory responses and to simulate the neural environment in various CNS disorders. However, despite much effort, the mechanism of astrocyte activation such as their responses to the TLR ligands and IL‐1 remain highly debated. We compared highly pure primary mouse and human astrocyte cultures in their ability to produce proinflammatory mediators (termed “A1”) and immunoregulatory mediators (termed “A2”) in response to LPS, poly IC, and IL‐1 stimulation. In human astrocytes, IL‐1 induced both A1 and A2 responses, poly IC induced mostly A2, and LPS induced neither. In mouse astrocytes, LPS induced mostly an A1‐predominant response, poly IC induced both A1 and A2, and IL‐1 neither. In addition, mouse astrocytes produce abundant IL‐1 protein, whereas human astrocytes did not, despite robust IL‐1 mRNA expression. Of the TLR4 receptor complex proteins, human astrocytes expressed TLR4 and MD2 but not CD14, whereas mouse astrocytes expressed all three. Mouse astrocyte CD14 (cell‐associated and soluble) was potently upregulated by LPS. Silencing TLR4 or CD14 by siRNA suppressed LPS responses in mouse astrocytes. In vivo, astrocytes in LPS‐injected mouse brains also expressed CD14. Our results show striking differences between human and mouse astrocytes in the use of TLR/IL‐1R and subsequent downstream signaling and immune activation. IL‐1 translational block in human astrocytes may be a built‐in mechanism to prevent autocrine and paracrine cell activation and neuroinflammation. These results have important implications for translational research of human CNS diseases. GLIA 2014;62:999–1013
Oxytocin facilitates the sensation of social stress
Authors: Eckstein Monika , Scheele Dirk , Weber Kristina , Stoffel‐Wagner Birgit , Maier Wolfgang , Hurlemann René
Published: March 2014

Essentially all social species experience social stress which can be a catalyst for detriments in mental and physical health. The neuropeptide oxytocin (OXT) has been shown to produce anxiolytic and antistress effects, thereby qualifying the OXT system as a promising drug target in the treatment of stress‐related disorders. However, recently it has been shown that OXT can have anxiogenic effects as well. In the present study, we used functional magnetic resonance imaging to scan the brains of 60 healthy men while they were exposed to social stress after they received either intranasal OXT (24 IU) or placebo treatment. Although OXT administration did not alter salivary cortisol levels as a surrogate marker of stress axis activity, our participants initially reported an increment in perceived social stress. This behavioral effect was paralleled on the neural level by increased activity in the precuneus and cingulate cortex. Taken together, our results support the hypothesis that OXT can induce a self‐referential processing bias which facilitates the sensation of social stress in the absence of altered endocrine responses. Hum Brain Mapp 35:4741–4750, 2014. © 2014 Wiley Periodicals, Inc.
Depicting the inner and outer nose: The representation of the nose and the nasal mucosa on the human primary somatosensory cortex (SI)
Authors: Gastl Mareike , Brünner Yvonne F. , Wiesmann Martin , Freiherr Jessica
Published: March 2014

The nose is important not only for breathing, filtering air, and perceiving olfactory stimuli. Although the face and hands have been mapped, the representation of the internal and external surface of the nose on the primary somatosensory cortex (SI) is still poorly understood. To fill this gap functional magnetic resonance imaging (fMRI) was used to localize the nose and the nasal mucosa in the Brodman areas (BAs) 3b, 1, and 2 of the human postcentral gyrus (PG). Tactile stimulation during fMRI was applied via a customized pneumatically driven device to six stimulation sites: the alar wing of the nose, the lateral nasal mucosa, and the hand (serving as a reference area) on the left and right side of the body. Individual representations could be discriminated for the left and right hand, for the left nasal mucosa and left alar wing of the nose in BA 3b and BA 1 by comparing mean activation maxima and Euclidean distances. Right‐sided nasal conditions and conditions in BA 2 could further be separated by different Euclidean distances. Regarding the alar wing of the nose, the results concurred with the classic sensory homunculus proposed by Penfield and colleagues. The nasal mucosa was not only determined an individual and bilateral representation, its position on the somatosensory cortex is also situated closer to the caudal end of the PG compared to that of the alar wing of the nose and the hand. As SI is commonly activated during the perception of odors, these findings underscore the importance of the knowledge of the representation of the nasal mucosa on the primary somatosensory cortex, especially for interpretation of results of functional imaging studies about the sense of smell.Hum Brain Mapp 35:4751–4766, 2014. ©2014 Wiley Periodicals, Inc.
Efficient One‐Pot Synthesis of Novel Spirooxindole‐Fused Phosphorous Heterocycle Derivatives by a Three‐Component Domino Reaction
Authors: Liu Rendie , Wu Mingshu , Li Guozhu
Published: March 2014

A highly efficient, catalyst‐free, and regioselective synthesis of structurally diverse spirooxindole‐fused phosphorous heterocycle derivatives was constructed in good yields by means of a three‐component domino reaction of isatins, dichlorophenylphosphine or phenyl phosphorodichloridite, and o‐aminophenol in tetrahydrofuran reflux. The advantages of this method include high efficiency, mild reaction conditions, and environmentally benign reagents. These spirooxindole‐fused phosphorous heterocycles are promising candidates for drug discovery.
Numerical Investigation of Double Diffusive Mixed Convection Laminar Flow in Two Sided Lid Driven Porous Cavity
Authors: Agarwal Lokesh , Satheesh A. , Mohan C.G.
Published: March 2014

This paper presents the numerical study of mixed convection in a two‐sided lid driven porous cavity due to temperature and concentration gradients. The top and bottom walls are stationary and insulated. The left and right walls are moving at an equal velocity (Vo) in the same direction. The temperature and concentration are kept high at the right wall and low at the left wall. The governing equations are discretized using finite volume method. The pressure–velocity coupling is performed by the SIMPLE algorithm. A third order differed QUICK scheme is applied at the inner nodes and a second order central difference scheme is used at the boundary nodes. The flow behavior and heat transfer are analyzed for different nondimensional numbers, such as, 1 × 10−4 ≤ Ri ≤ 10, 1 × 10−4 ≤ Da ≤ 0.1 and 0.7 < Pr < 10. The present numerical results are compared with the literature and are in good agreement. For the above selected nondimensional numbers, the heat and fluid flow behavior is investigated using local and average Nusselt (Nu) and Sherwood (Sh) numbers. Results show that the convection flow is significant up to Da = 0.1, beyond that the effect of porosity is negligible. The effect of Prandtl number (Pr) on average Nu is found to increase significantly.
Laminar Momentum and Heat Transfer in a Channel with a Built‐In Tapered Trapezoidal Bluff Body
Authors: Dhiman Amit , Verma Shipra , Ghosh Ritwik
Published: March 2014

Effects of wall confinements on the laminar flow and heat transfer around a heated tapered trapezoidal bluff body are investigated numerically in the confined domain (Reynolds number, Re = 1 to 40; blockage ratio = 0.125 to 0.5; and Prandtl number, Pr = 0.71). The onset of flow separation is found between Re = 4 and 5 for the blockage ratio of 0.125 and between Re = 5 and 6 for the blockage ratios of 0.25 and 0.5. If compared with a long circular obstacle on the basis of equal projected area, the total drag coefficient of the trapezoidal cylinder is found to be larger than the circular one, but an opposite trend is observed for the heat transfer. The augmentation in heat transfer for trapezoidal and circular cylinders is found to be approximately 46, 72, 74, and 65 percent for Re = 1, 5, 10, and 40, respectively for the blockage ratio of 0.25. The maximum enhancement in heat transfer for a tapered trapezoidal bluff body with respect to a square bluff body is found to be approximately 104 percent and 101 percent for blockage ratios of 0.25 and 0.5, respectively. Finally, simple correlations of wake length, drag, and average cylinder Nusselt number are established.
An Analytical Solution for Fully Developed Forced Convection in Triangular Ducts
Authors: Shahmardan M.M. , Sedaghat M.H. , Norouzi M.
Published: March 2014

In this paper, an exact analytical solution for fully developed convective heat transfer in equilateral triangular ducts under constant heat flux at the walls is presented. The previous studies have been performed using numerical methods and to the knowledge of authors, this study is the first EXACT analytical solution about the heat convection in triangular ducts. Here, the finite series expansion method is used to derive the closed form of dimensionless temperature distribution. The Nusselt number and dimensionless temperature at the center of the cross section were calculated equal to 28/9 and 5/9, respectively. The present analytical solution could be useful in analysis of the heat convection in microfluidics and designing compact heat exchangers.