bluuebunny/crossref_metadata_2025 huggingface dataset:
SÍNDROMES SENSITIVAS CENTRAIS
Authors: Menezes Isabel Cristina Borges de
Published: May 2023

A síndrome talâmica tem etiologia vascular (artéria cerebral posterior, artérias talassogênicas), de origem neoplásica, infecciosa, inflamatória e metabólica. Os sinais e sintomas são sensitivos e motores como: hemiparesia leve transitória, hemicoreoatetose, hemi-hipoestesia, hiperalgesia, alodinia e hemiataxia com astereognosia de intensidade variável, com enfoque na dor talâmica.
YAPAY ET ÜRETİMİNDE TEKNOLOJİK GELİŞMELER VE ENDÜSTRİSİNİN GELECEĞİ
Authors: ÇAKMAK Ömer , ERGENE Erdi , ACARÖZ Ulaş , ALDEMİR Tuba
Published: May 2023

Although meat consumption is one of the most important conditions of healthy and a balanced diet, it becomes difficult to meet the demand per capita due to the increase in the world population. The change in consumer preferences and the constant increase in the use of resources in the traditional meat production method, the supply-demand imbalance that arises makes it necessary to turn to alternative protein sources. Because; genetically modified organisms (GMOs), meat alternatives obtained from plant-based sources, and cultured meat are among the emerging ideas for meeting protein needs. Artificial meat production is presented as a potential solution to reduce the serious problems related to nutrition and public health, climate change, environmental pollution, sustainability and animal welfare originating from traditional meat production. Preparation of artificial meat production procedures, providing taste criteria, determining risk analyzes and making necessary legal arrangements are important in terms of being among sustainable food sources. At the same time, it is important to specify the advantages in the production process against the problem of trust in consumer perception due to the high cost of artificial meat and ethical and religious beliefs. This article; It has been compiled from research on the historical development process of artificial meat production, production methods, alternative protein sources, advantages and disadvantages, the future of the artificial meat industry, consumers' attitudes and concerns towards artificial meat.
PERSEPSI MASYARAKAT TERHADAP SISTEM PELAYANAN ONLINE DALAM PENGURUSAN AKTA KELAHIRAN DI KANTOR KELURAHAN MADE
Authors: SUDANTO MUHAMMAD RAFIF , IKMAL NOVITA MAULIDA
Published: May 2023

Tujuan dari penelitian ini adalah untuk mengetahui bagaimana Persepsi Masyarakat Terhadap Sistem Pelayanan Online Dalam Pengurusan Akta Kelahiran Di Kantor Kelurahan Made. Persepsi Masyarakat dapat dilihat dari tiga indikator yaitu Penyerapan terhadap rangsang, Pengertian atau pemahaman, dan Penilaian atau evaluasi. Sedangkan Sistem Pelayanan Online meliputi Efisiensi (Efficiency), Pemenuhan kebutuhan (Fulfillment), Ketersediaan sistem (System Availability), dan Privasi (Privacy). Dalam hal ini peneliti mengambil Responden total sebanyak 42 orang, terdiri dari seluruh masyarakat yang masuk dalam ruang lingkup kelurahan made. Metode penelitian ini adalah menggunakan jenis penelitian Deskriptif Kuantitatif, dengan pengambilan data menggunakan kuisioner dan observasi, teknik analisis data yang digunakan antara lain, yaitu Uji Validitas. Uji Reliabilitas, Uji Normalitas, Uji Regresi Linier Sederhana, Uji Koefisiensi Determinansi Regresi, dan Pengujian Hipotesis. Hasil dari Uji Validitas Persepsi Masyarakat terdapat 9 pertanyaan dan Sistem Pelayanan Online terdapat 10 pertanyaan. Dari masing-masing pertanyaan semuanya valid dan tidak ada yang valid. Berdasarkan analisis kuantitatif dilakukan perhitungan dengan analisis parsial diperoleh Koefisien (r) sebesar 0,001. Dan hasil uji t hitung = 0,229 dengan nilai signifikan 0,820 > 0.05. karena nilai signifikansi 0,820 > 0,05 maka dapat dikategorikan tidak signifikan. Sehingga menunjukkan hipotesis tidak ada pengaruh Persepsi Masyarakat Terhadap Sistem Pelayanan Online Dalam Pengurusan Akta Kelahiran Di Kantor Kelurahan Made tidak dapat diterima dan tidak signifikan. Dilihat dari indikator yang digunakan oleh peneliti menunjukkan bahwa Persepsi Masyarakat Terhadap Sistem Pelayanan Online Dalam Pengurusan Akta Kelahiran Di Kantor Kelurahan Made belum cukup baik.
STRATEGI PENGEMBANGAN OBJEK WISATA KAMPUNG WAEREBO KECAMATAN SATAR MESE BARAT KABUPATEN MANGGARAI NUSA TENGGARA TIMUR
Authors: SANGKAK ADRIANUS , IKMAL NOVITA MAULIDA
Published: May 2023

Penelitian ini bertujuan untuk mendeskripsikan strategi pengembangan objek wisata kampun waerebo di kecamatan satar mese barat kabupaten manggari. Penelitian ini merupakan penelitian deskriptif dengan pendekatan kualitatif. Teknik pengumpulan data menggunakan wawancara, observase, dan dokumentasi. Teknik analisis data yang digunakan yaitu reduksi, display data, dan penerikan kesimpulan. Keabsahan data dengan menggunakan trangulasi sumber, triangulasi Teknik, dan triangulasi waktu. Hasil penelitian dapat diketahui bahwa strategi pengembangan objek wisata kampung waerebo di kecamatan satar mese barat yang di kembangkan oleh dinas pariwisata kabupaten mamnggari dan masyarakat lokal belum sepenuhnya dilakukan dengan maksimal, penyediaan sarana dan prasaranan objek wisata kampung werebo masih sangat terbatas yang tersedia di lokasi objek wisata masih memerlukan pembangunan dan perbaiki serta perawatan sehingga tidak menghambat kegiatan kepariwisataan, promosi yang dilakukan dengan menggunakan media social belum di lakukan optimal serta sumber daya manusia yang terbatas dari segi kualitas dan kuantitas pada objek wisata. Factor pendukung dari setiap objek wisata memiliki daya Tarik dan keunikan masing-masing.
KUALITAS PELAYANAN REHABILITASI SOSIAL BAGI PENYEMBUHAN KORBAN PENYALAHGUNAAN NARKOBA
Authors: ABDILLAH GARIEN WAHYU , SULISTYOWATI ARINI
Published: May 2023

Penelitian ini bertujuan untuk mengetahui penanganan korban narkoba di yayasan rehabilitasi sosial Rumah Sehat Orbit Surabaya selain itu juga untuk mengatahui kesesuaian penanganan di yayasan rehabilitasi Rumah Sehat Orbit Surabaya. Penelitian ini merupakan penelitian hukum empiris yang bersifat deskriptif. Lokasi penelitian di Yayasan Rehabilitasi Rumah Orbit Surabaya. Jumlah responden 3 orang yaitu: 1) Bapak Munif selaku koordinator yayasan dan 2) mbak Ike selaku konselor Yayasan Rehabilitasi 3) Andre selaku klien Rehabilitasi. Jenis data yang digunakan adalah data primer dan data sekunder. Data primer merupakan data utama, sedangkan data sekunder digunakan untuk mendukung data primer. Teknik pengumpulan data yang digunakan adalah melalui wawancara dan penelitian kepustakaan. Analisis data kualitatif dengan model interaktif data yang terdiri dari reduksi data, penyajian data, menarik kesimpulan. Berdasarkan penelitian ini diperoleh hasil bahwa Di Yayasan Rehabilitasi Rumah Sehat Orbit Surabaya menggunakan metode utama dalam penanganan klien narkoba yaitu rehabilitasi dengan metode sosial metode-metode penanganan yang digunakan juga tidak melanggar dan telah sesuai dengan aturan perundangan yang berlaku yaitu Undang-Undang Nomor 22Tahun 1997 tentang Narkotika dalam hal rehabilitasi korban narkoba. Meskipun dalam pelaksanaannya masih banyak kekurangan dalam penanganan korban narkoba namun metode-metode penanganan yang di gunakan sudah cukup efektif untuk menyembuhkan para korban narkoba di Yayasan Rehabilitasi Rumah Sehat Orbit Surabaya Bahwa dilihat dari sudut pandang pelayanan penanganan korban narkoba di Yayasan Rehabilitasi Mental Sinai Sukoharjo sudah sesuai. Dalam penanganan korban sangat mengedepankan hak-hak asasi korban untuk kembali hidup normal tanpa ketergantungan narkoba. Kemudian di Yayasan Rehabilitasi Rumah Sehat Orbit Surabaya sangat melindungi korban dari ketergantungan narkoba dengan melakukan bimbingan sosial. Jadi dengan mengedepankan hak -hak asasi korban dan melakukan perlindungan terhadap korban maka telah sesuai.
EFEKTIFITAS PEMBERDAYAAN EKONOMI MASYARAKAT DESA MELALUI BUMDES BAROKAH SEJAHTERA (STUDI DI DESA RANDU PADANGAN, GRESIK)
Authors: YULITA VENNA , SUPRIYANTO SUPRIYANTO
Published: May 2023

Masalah Kemiskinan di Indonesia telah menjadi perhatian banyak pihak untuk sekian lama. Dalam sejumlah studi menunjukan bahwa jumlah penduduk miskin dan termiskin di pedesaan masih cukup banyak.Perencanaan dan implementasi pembangunan seharusnya berisi untuk memberdayakan mereka, sehingga mereka memiliki akses pada sumber-sumber ekonomi. Saat ini pemerintah daerah tengah mendorong pemerintah desa untuk mengembangkan Badan Usaha Milik Desa (BUMDesa). Peranan BUMDesa dalam penyelenggaraan pemerintahan desa dan pemberdayaan masyarakat desa berdasarkan prakasarsa masyarakat berfungsi untuk menstimulasi, memfasilitasi dan melindungi serta memberdayakan kesejahteraan ekonomi masyarakat pedesaan. Penelitian ini mengambil objek BUMDesa Barokah Sejahtera, Desa Randupadangan Kecamatan Menganti-Gresik yang bertujuan untuk mengetahui tingkat efektivitas pencapaian pemberdayaan ekonomi masyarakat desa. Penelitian ini merupakan jenis penelitian lapangan (Field Reseach), penelitian ini menggunakan metode dekriptif-kualitatif, dimana peneliti mengumpulkan data dengan observasi, wawancara, dan dokumentasi. Sumber informan ditentukan secara purpose sampling yaitu Kepala desa Randupadangan, sekretaris desa Randupadangan, Direktur BUMDesa Barokah Sejahtera, Sekretaris BUMDesa Barokah Sejahtera, Pengelola unit usaha BUMDesa Barokah Sejahtera toko masyarakat dan warga masyarakat Desa Randupadangan dengan total tujuh informan. Hasil penelitian menunjukan bahwa program pemberdayaan ekonomi masyarakat desa oleh BUMDesa Randupadangan ada empat, dua baru mulai beroperasi satu tahun kemudian yaitu Toko ATK dan Jasa Digital, yang satu lagi baru tahap perencanaan dan uji coba yaitu unit usaha pertanian, dan pengadaan peralatan pertanian. Dan yang terealisasi cukup baik baru satu, yaitu unit usaha simpan pinjam. Untuk indikator efektivitas menggunakan teori dari Makmur 2011:7-8 dengan delapan indikator efektivitas program yaitu, Ketepatan penentuan waktu, Ketepatan perhitungan biaya, Ketepatan dalam pengukuran keberhasilan, Ketepatan dalam menentukan pilihan, Ketepatan berpikir, Ketepatan dalam melakukan perintah, Ketepatan dalam menentukan tujuan, Ketepatan sasaran. Hasil penelitian menunjukan bahwa indikator ketepatan sasaran program, dan ketepatan penentuan waktu dan ketepatan berpikir sudah cukup efektiv, sedangkan untuk kelima lainnya masih belum efektiv.
A Direct Connection between the Wake and the Former Host Galaxy of a Proposed Runaway Supermassive Black Hole
Authors: van Dokkum Pieter
Published: May 2023

This Research Note presents VLT B-band imaging of a candidate runaway supermassive black hole that was recently discovered in HST/ACS F606W+F814W imaging. The ACS data show an extremely thin, linear feature at z = 0.964 that points toward a compact galaxy at the same redshift. There is a gap between the feature and the compact galaxy, which means that the proposed causal connection between the two objects is not definitive. We show here that the linear feature extends all the way to the compact galaxy in the B-band, with no gap. The B-band morphology is difficult to reconcile with models where the compact galaxy and the linear feature are independent objects, and in particular with the proposal of Sanchez Almeida et al. that the linear feature is an edge-on disk galaxy.
Serum levels of leptin and adiponectin in patients with autoimmune Hashimoto's thyroiditis
Authors: Tomov Desislav G. , Levterova Boryana A. , Troev Dimitar M. , Miteva Maria Z. , Mihaylova Valentina N. , Uzunova Yordanka I. , Divarova Vidka V. , Orbetzova Maria M.
Published: May 2023

Introduction: Adipose tissue is immunologically and hormonally active, and these effects are mediated largely by adipocytokines. Thyroid hormones regulate metabolism and organ function, and Hashimoto’s thyroiditis (HT) is the most common autoimmune disease affecting thyroid function.

Aim: To evaluate the levels of the adipocytokines leptin and adiponectin in patients with autoimmune HT, and to perform a comparative intragroup analysis in patients with different stages of gland functional activity, and in a control group.

Materials and methods: Ninety-five patients with HT and 21 healthy controls were enrolled in the study. Venous blood was taken without anticoagulants after at least 12 hours of fasting, and serum samples were frozen at −70°C until analysis. Serum levels of leptin and adiponectin were determined by an enzyme-linked immunosorbent assay (ELISA).

Results: Serum levels of leptin in HT patients were higher than those in the control group (4.5±5.2 ng/mL vs. 1.9±1.3 ng/mL). The hypothyroid patient’s group showed significantly higher levels of leptin than those of the healthy controls (5.1±5.2 ng/mL vs. 1.9±1.3 ng/mL), (p=0.031). Leptin levels correlated positively with body mass index (r=0.533, p<0.001), triglycerides (r=0.223, p=0.033), and immunoreactive insulin (r=0.488, p<0.001) levels. Serum adiponectin concentrations were higher in euthyroid HT patients than in the other groups, but the difference was not statistically significant (p=0.68). We found a positive correlation between adiponectin and HDL cholesterol levels (r=0.442, p<0.001), and negative with body mass index (r=−0.217, p=0.03), and immunoreactive insulin (r=−0.341, p=0.002).

Conclusions: The results of this study suggest that leptin has a stronger effect than adiponectin in Hashimoto’s thyroiditis, which can be used to develop new therapeutic agents that modify its effect in the organism.
Anterior chest wall resection and reconstruction due to recurrent chondrosarcoma: a case report
Authors: Alexieva Magdalena , Yankov Georgi
Published: May 2023

Chest wall chondrosarcoma is a rare malignant tumor with aggressive biological behavior. The only available treatment for primary or recurrent chondrosarcoma consists of radical surgical resection because of its well-known chemo- and radioresistance. Repeated resection for recurrent chondrosarcoma is challenging because of the altered anatomy, scarring, harvested muscles, and close proximity to vital thoracic organs. We present an uncommon case of recurrent chest wall chondrosarcoma resected in the Department of Thoracic Surgery, which we reconstructed with Symbotex mesh and reinforced by omentoplasty. In addition, we created a brief review of the prevalence, diagnostics, surgical treatment, reconstructive options, and prognosis for this condition.
Accessibility to and awareness of rheumatology care provided by a nurse - a pilot study
Authors: Stoilova Stefka , Geneva-Popova Mariela , Taneva Daniela
Published: May 2023

Introduction: Good medical care depends both on the access to specialists and awareness of patients and healthcare professionals.

Aim: The purpose of this study was to assess the accessibility to rheumatology outpatient care and the awareness of patients with inflammatory joint diseases with regard to the types of sources and preferences of sources for obtaining information related to their disease and treatment, as well as to establish the extent to which this information is useful to patients.

Materials and methods: A pilot, cross-sectional, single center, anonymous study was conducted among adult patients with inflammatory joint diseases who were monitored in an outpatient rheumatology room at St George Diagnostic and Consultative Center in Plovdiv. A total of 56 patients were monitored. The questionnaire contained 56 questions, divided into 5 main groups: 1. questions about the disease, 2. questions about the sociodemographic profile of the patients, 3. questions about accessibility to specialized healthcare, 4. questions about the role of the nurse in the training of patients with inflammatory joint disease, and 5. questions evaluating the attitude to the monitoring medical team. The data were analyzed with IBM SPSS V.26, at a statistical significance level of p<0.05 for all analyses.

Results: Women predominated among the patients under observation (37, 66%), as well as patients in the age group of 50-79 years (46, 82%). Twenty-four (42.9%) were the patients attending the consulting room twice a year. On-the-spot booking in the consulting room was preferred mainly among patients who lived within 50 km (3/16, 19%), while the rest of the patients preferred booking appointments by phone. Forty-five (80%) patients of the total number of patients used subcutaneous biological agents. Among them, the patients whose first application was performed by a nurse in a rheumatology room predominated (44 patients, 96%). All respondents (56, 100%) indicated that they had received self-injection training from a healthcare professional.

Conclusion: Patients with inflammatory joint diseases need information to help them manage issues related to their disease and treatment, as well as cope with their physical and psychological needs. Our study shows that patients most commonly use a combination of information sources – they get information from a doctor or from a healthcare professional, i.e. a nurse. We highlighted in the study the crucial role of nurses in improving the access of patients to specialized rheumatology care and satisfying patients’ information needs.
When two viruses collide: coronavirus disease after hepatitis B virus reactivation
Authors: Komitova Radka T. , Kevorkyan Ani , Vasilev Petur , Golgocheva-Markova Elitsa , Atanasova Maria
Published: May 2023

The COVID-19 pandemic has exploded since the first cases were reported in Wuhan in December 2019, engulfing the globe. Many infected individuals are asymptomatic or have a mild or moderate disease. A subset of people with advanced age, the immunocompromised and those with chronic diseases, are prone to serious-to-critical illness. We report a fatal case of metastatic colorectal cancer survivor who developed COVID-19 after clinically reactivated hepatitis B virus (HBV) due to chemotherapy. The patient’s COVID-19 illness was supposed to be related to her recent medical evaluation. Although being diagnosed with chronic HBV infection for decades, she was not treated with nucleotide analogue and the possibility to preclude HBV reactivation was missed. Moreover, infectious control practices must be draconian in order to save such a fragile population from infections.
New localities and lineages of the Atlas dwarf lizard Atlantolacerta andreanskyi identified using mitochondrial DNA markers
Authors: Harris D. James , Varela-Pereira A. Carolina , Faria J. Filipe , S’Khifa Abderrahim , Vasconcelos Diana , Marshall Jonathon C. , Slimani Tahar
Published: May 2023

Atlantolacerta andreanskyi (Werner, 1929) is an endemic lizard from the High Atlas Mountains region of Morocco. A previous molecular assessment of this species using mitochondrial and nuclear DNA markers uncovered extensive genetic diversity with seven lineages indicative of a species complex. A morphological assessment of six of these lineages did not establish simple diagnostic features, and proposed these should be considered as a cryptic species, while highlighting the need for greater sampling across the range. In this study, we sampled 8 individuals from 5 previously unsampled localities and carried out genetic analyses to compare these populations to the known variation. Phylogenetic reconstruction based on mitochondrial DNA markers (12S rRNA and ND4) corroborates the previously described lineages and identified a new one. Interestingly, the two samples that account for this newly identified lineage have been collected from distinct localities – M’goun and Toumliline – that form a sister taxon to the population of Jbel Azourki.
Existence and stability of fuzzy Pareto-Nash equilibria for fuzzy constrained multi-objective games with fuzzy payoffs
Authors: Li Wen , Li Deyi , Feng Yuqiang , Zou Du
Published: May 2023

A new class of fuzzy constrained multi-objective games with fuzzy payoffs (FCMGFPs) is considered in this paper. First, Berge's maximum theorem for the fuzzy-vector-valued function is obtained. Based on this theorem and the Fan-Glicksberg fixed point theorem, the existence theorem of the fuzzy Pareto-Nash equilibrium for the FCMGFP is established. Second, the abstract rationality function for the FCMGFP is given by using a nonlinear scalarization function of interval vectors. Finally, a series of results, such as structural stability ($ (\gamma, \epsilon) $-stability) and robustness to $ \epsilon $-equilibrium ($ (\gamma, \epsilon) $-robustness), are obtained.
Diferencias estratégicas de las majors del petróleo ante la transición energética: opciones, motivaciones e implicaciones
Authors: Fernández Sánchez Rafael
Published: May 2023

El trabajo propone un marco para analizar las opciones estratégicas de las majors del petróleo ante el reto de la transición energética, considerando simultáneamente dos cuestiones que están interrelacionadas: el objetivo de reducir las emisiones de gases de efecto invernadero y el objetivo de adaptarse a los cambios que se están produciendo en la demanda de energía. Haciendo uso de este marco, se pregunta en qué medida los cambios que se están produciendo en la demanda energética han sido una condición necesaria, o incluso suficiente, para que las compañías europeas hayan iniciado estrategias de diversificación. Igualmente se pregunta si la diversificación del negocio hacia otras actividades no vinculadas a los hidrocarburos ha sido condición necesaria, o incluso suficiente, para que estas empresas hayan empezado a asumir la reducción de emisiones como un objetivo estratégico. Por último, el trabajo analiza el impacto de esas estrategias de diversificación sobre el desarrollo de las energías renovables.
Multi-method sensory approach to describe the effect of microwave-assisted extraction and addition of stems on the mouthfeel sensations of Bonarda wines from Mendoza (Argentina)
Authors: Alvarez Gaona Izmari Jasel , Fanzone Martín , Sari Santiago , Catania Anibal , Coronado Ignacio , Jofré Viviana , Zamora María Clara , Galmarini Mara V.
Published: May 2023

The Bonarda variety has been used as a base for common red wines due to its contribution to color and low level of astringency as a consequence of its relative low tannin concentration. The use of Microwave- Assisted Extraction (MWE) accelerates the maceration process, improving the diffusion of grape compounds into the must, while the stems addition during maceration/fermentation constitutes a sustainable technological alternative for increasing tannins at no additional cost. The present experimental design consisted of ten treatments (in triplicate), obtained combining both technologies. Two maceration strategies were applied: Control must (C) which was not treated, and must treated with microwavedassisted extraction after grape crushing. These were combined with five Stem-contact conditions (ST): C without ST, 50% ST addition, addition of 50% ST previously treated with MWE, 100% ST addition, and addition of 100% ST previously treated with MWE. The effect of the winemaking technologies on wine mouthfeel sensations was evaluated by different (static and dynamic) sensory methods: Sorting Task; Check-All-That-Applies (CATA) with different textiles as trans-modal references; and Temporal Dominance of Sensations (TDS). CATA evaluation revealed that three of the wine samples differed in their description. These were then dynamically described showing subtle differences in their TDS curves. The sequentiality of dominant sensations showed that the MWE treatment of the grapes and the combination ST with MWE did not modify dramatically mouthfeel sensations in Bonarda wines.
Perception of mineral character in Sauvignon blanc wine: inter-individual differences
Authors: Parr Wendy Veronica , Ballester Jordi , Peyron Dominique , Grose Claire , Valentin Dominique
Published: May 2023

Of the descriptors employed to characterize wine organoleptically, minerality is arguably one of the most enigmatic. The aim of the work described in this article was to delineate the nature of perceived minerality in Sauvignon wine, specifically its sensorial reality for experienced wine professionals from France and New Zealand. Participants evaluated 16 Sauvignon blanc wines (8 French; 8 New Zealand) under three conditions, ortho-nasal olfaction, palate only (Nose-clip condition), and by full tasting (global perception). Data from the global condition only are reported here. Key results include: i) that although there were quantitative differences in perception of minerality as a function of culture, there was substantial agreement conceptually between French and New Zealand participants in terms of the sensorial experience of minerality; and ii) that perceived minerality associated significantly with other key wine descriptors, notably presence of citrus, stone-related characters (e.g., flinty or chalky/calcareous notes), and reductive notes, along with absence of Sauvignon varietal characteristics (passion fruit; green notes). Of particular interest, no significant, direct association was found between perceived sourness/acidity and minerality judgments for either culture.
Evaluating the impact of a fungal-origin chitosan preparation on Brettanomyces bruxellensis in the context of wine aging
Authors: Nardi Tiziana , Vagnoli Paola , Minacci Andrea , Gautier Sandrine , Sieczkowski Nathalie
Published: May 2023

Brettanomyces bruxellensis and the consequences of its development in wines are a continuous threat for wine quality. In this context, chitosan of fungal origin was introduced as a new tool to control B. bruxellensis in the context of winemaking. Recent studies have showed the impact of a fungal origin chitosan application on wines contaminated with B. bruxellensis, leading to the elimination of B. bruxellensis cells. In these studies, the chitosan preparation was added, the wine racked off after 10 days and the efficiency of the treatment was evaluated in a short delay after the treatment. This study focused on the evaluation of the impact of different addition protocols of an enological chitosan preparation on B. bruxellensis population evolution and volatile phenols content along the aging, up to 9 months. The results confirm the interest of fungal origin chitosan as a preventive tool to control B. bruxellensis in the context of wine aging.
Drying/encapsulation of red wine to produce ingredients for healthy foods
Authors: Alvarez Gaona Izmari Jasel , Rocha-Parra Diego , Zamora Maria C. , Chirife Jorge
Published: May 2023

Epidemiological evidence indicates that moderate consumption of red wine reduces the incidence of coronary disease, atherosclerosis, and platelet aggregation. Wine is very rich in antioxidant compounds because of their phenolic components. However, many people for ethnic, social or religious reasons do not consume wine. Drying/encapsulation of red wine in the presence of adequate carbohydrates leads to water and more than 99% of alcohol removal; a glassy amorphous microstructure is obtained in which the wine’s phenolic compounds are entrapped. The resulting product is a free flowing powder which could be used for the polyphenol enrichment of healthy foods and/or drink powders, as well as in the pharmaceutical industry. The wine industry may take advantage of the dried/encapsulated red wine using as a raw material red wines which have little commercial value for different reasons; i.e. poor quality due to raw material, unfavourable climatic conditions, or wines that suffered some alteration during the wine making process. Dry encapsulated wine may be a new alternative to red wines that cannot be sold as such for different reasons, and open new opportunities to diversify wine products.
The Gap between Theory and Practice in Primary Mathematics: PGCE Students’ Perspectives on ‘Teaching for Mastery’.
Authors:   , Goodland James
Published: May 2023

This thesis applies a constructivist perspective to the analysis of primary PGCE students’ perceptions of the theoretical and practical aspects of their teacher training. It provides a discussion of the prevailing discourses in initial teacher education as well as that of the ‘mastery’ curriculum for mathematics that is prevalent in primary schools in England. The study takes a ‘partially mixed method’ approach to the collection of data; data were collected from a questionnaire given to the whole cohort of PGCE students who were pursuing a strength in mathematics at a medium-sized university in the West of England in the academic year 2017-18. This was used in conjunction with semi-structured telephone interviews that were conducted with a sample of eight of the students in the spring and summer terms of 2018. A Friedman Test of differences as well as a post-hoc Nemenyi Test was conducted on questionnaire data to highlight significant findings. The interview data underwent thematic analysis. The study finds that students do encounter difficulties when implementing the theoretical aspects of their training in practice and that this is influenced by a number of enabling and constraining factors both at university and at school. The thesis makes a methodological contribution in arguing the case for the use of telephone interviews in educational research and in exemplifying issues around insider/outsider fieldwork. It also makes recommendations for professional practice in terms of partnership between schools and higher education institutes as well as recommendations about training for mentors and those supporting primary PGCE students in schools. Finally, the thesis identifies a so called ‘matryoshka effect’ that inhibits students’ ability to make use of their learning from university in school and it argues the case for a ‘matryopraxis’ approach to learning that uses these research findings for improving the training of primary education students.
Joy and pain – a visit into scholarship: Managers’ lived experience as part-time doctoral researchers Towards the development of a conceptual framework.
Authors:   , Haegele Daniela
Published: May 2023

This research provides an in-depth study of the lived experience of German managers who undertake part-time doctoral study at a British University. The Doctor of Business Administration (DBA), as a professional doctorate with its initial structured taught phase, is the subject of investigation. It is of particular interest to German business professionals as the national education system does not provide opportunities to undertake part-time doctoral study, especially in such a format. The focus of this study is managers’ experienced stress and the coping strategies applied as part-time DBA students, within their context and through the perspectives of other lifeworlds. Previous research on the doctoral experience has not focused on the DBA and, specifically, its related stress, or by applying interpretative phenomenological analysis (IPA). A case-by-case and across cases analysis is used to provide a holistic understanding of managers’ lived experience in their context. Four student cases were explored over 8 to 10 months through several interviews, with the students, their supervisors, their partners, and their work colleagues. The analysis generated six superordinate themes: Learning and challenging identity, balancing: negotiation and adaption, managing emotional fluctuations, relying on significant others, motivating and persisting and moving forward. Van Manen’s (1990) four existentials – (temporality, spatiality, corporeality and relationality) as the core structure of lived experience – provide a theoretical basis to illustrate the relationships and dynamics of those themes in a holistic conceptual framework of DBA students’ lived experience. Central in this framework is students’ research development as embodied practice, challenged by destabilising forces (experienced as stress) primarily arising from issues within temporality and relationality. In response, students seek control in the form of maintaining balance by negotiation and adaption, managing emotional fluctuations, and seeking support from significant others. Development happens in a cyclic fashion, where a maturation process appears to be characterised by passing a threshold while experiencing pain. Core findings reveal most stressors arise from the discrepancy between an individual’s mindset as a manager and the academic thinking and rigour required of a DBA. Being a ‘student’ in a novice role creates uncertainty and destabilises self-confidence and thus a manager’s identity. This illustrates that students’ research development requires learning and identity work. The findings illuminate the barrier between practitioner and academic thinking that DBA students need to overcome and emphasize the need for consideration in programme conception and acknowledgement by educators, supervisors, and prospective students of the individual’s process of development.
Aprendizagem Ativa e Tecnologias Digitais no Ensino de Área e Perímetro
Authors: Almeida Helber Rangel Formiga Leite de , Leonardo Maria Zilanda de Andrade
Published: May 2023

Este artigo apresenta elementos de uma pesquisa que objetivou verificar as potencialidades e limitações dos aplicativos de celular na aprendizagem de Área e Perímetro, por meio das metodologias de aprendizagem ativa. Os conteúdos foram trabalhados com alunos da 1ª série do Ensino Médio Técnico, de uma escola pública localizada em Itabaiana – PB. A pesquisa qualitativa, com abordagem exploratória e descritiva, foi desenvolvida de maneira remota devido à pandemia da Covid-19. Os dados, analisados à luz dos estudos de Moran (2012, 2013, 2018) e Mazur (2015), foram produzidos a partir de questionários, entrevistas semiestruturadas, capturas de telas, gravações de áudio e vídeo, observações e anotações. Durante a pesquisa, foram utilizadas as metodologias de aprendizagem ativa: Gamificação e Instrução por Pares. Com a pesquisa, evidenciou-se que atividades, envolvendo metodologias ativas e aplicativos para celular, podem potencializar a aprendizagem de Área e Perímetro.
Livros Didáticos do PNLD e a BNCC: Análise da Organização do Ensino de Equações de 2º Grau
Authors: Pereira Fernando Francisco , Doneze Iara Souza , Proença Marcelo Carlos de
Published: May 2023

Este artigo objetivou analisar a organização do ensino de Equações de 2º grau no 9º ano em livros didáticos. Para isso, recorreu-se a uma pesquisa exploratória de caráter bibliográfico em que o corpus de investigação constituiu-se das obras aprovadas no Plano Nacional do Livro Didático para o atual quadriênio (2020 - 2023) e que deveria ter como base a BNCC (2018). O corpus da investigação é constituído dos 11 livros didáticos. A categorização e análise dos dados baseou-se em três eixos: Abordagem introdutiva do estudo de Equações de 2º grau; Sequência evolutiva do estudo de Equações de 2º grau; Apresentação das atividades de aprendizagem de Equações de 2º grau. Como resultados, houve mudanças significativas quanto à introdução do conteúdo por meio de situações-problema e de contexto extra-matemático. Entretanto, constatou-se uma estagnação referente à estruturação dos tópicos e características dos exercícios, com similaridade ao período do Movimento Matemática Moderna.
Questões aritméticas, questões algébricas e escolha da operação: interrelações em uma revisão bibliográfica
Authors: Lopes Thiago Beirigo , Sá Pedro Franco de
Published: May 2023

Em aulas de Matemáticas, são comuns questionamentos como: “Essa continha é de mais ou de menos?”, “Está escrito ‘ganhou’, então a questão é de mais?”, e nem sempre a resposta dada pelo professor auxilia o estudante na compreensão do enunciado. Diante disso, essa pesquisa teve como objetivo estabelecer um panorama em relação ao que foi estudado sobre a escolha da operação aritmética em questões matemáticas e as interrelações com as ideias de questão aritmética e questão algébrica. É uma pesquisa bibliográfica de abordagem qualitativa, realizada por meio de busca no Google Acadêmico em idioma português e em inglês. Ficou evidenciado, após a análise de 35 publicações, que desde a década de 1970 há menção à escolha da operação em questões matemáticas e que as primeiras pesquisas encontradas foram em idioma inglês. Também foi constatado que essas pesquisas em idioma inglês, em grande parte, embasaram estudos em idioma português.
Identidades transnacionais como via para o universalismo genuíno: uma aproximação entre Léopold Senghor e Darcy Ribeiro (mediada por Gilberto Freyre e Leopoldo Zea)
Authors: Pereira da Silva Fabricio , Kozel Andrés
Published: May 2023

Este artigo propõe comparar a negritude em Léopold Senghor e o latino-americanismo em Darcy Ribeiro. Estamos principalmente interessados em apontar como a noção de “civilização” aproxima os dois autores: o entendimento da civilização negro-africana como parte constitutiva de uma futura “civilização do universal” em Senghor, e a ideia de “civilização emergente” em Ribeiro. A chave para a comparação (e aproximação) entre ambos está em seus usos de civilização. E isto fica mais evidente ao colocá-los em diálogo com Gilberto Freyre e Leopoldo Zea. A fim de facilitar este encontro, é do nosso interesse lançar mão particularmente do Freyre lusotropical, que em sua reflexão remete a um encontro global de civilizações, e do Zea de América en la historia, que, ele próprio um leitor de Freyre, procura definir a posição da América com base em uma releitura crítica – via Toynbee – da filosofia da história de Hegel. O artigo pretende ser uma contribuição à história das ideias (ou história intelectual), bem como um convite ao diálogo com abordagens mais filosóficas destinadas a discutir formas de pensar a unidade e a diversidade das culturas e, em particular, o lugar dos povos não europeus na história.
Vasopressin Modulates Endothelial and Fibroblast Gene Expression
Authors: Wang Yongqing
Published: May 2023

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Decreased Prevalence of Autoimmune Connective Tissue Diseases in Type 1 and Type 2 Diabetes
Authors: Abugharbyeh Aya , Khuder Sadik , Kahaleh Bashar
Published: May 2023

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Midostaurin in Advanced Systemic Mastocytosis: A Systematic Review and Meta-analysis
Authors: Abuhelwa Ziad
Published: May 2023

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Harmful Algal Bloom Impacts on Human Health: An Analysis of National Emergency Department Data in the U.S. from 2016 to 2018
Authors: French Benjamin
Published: May 2023

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Paraoxanase 1 Regulation of Cardiac Inflammation and Fibrosis in a Dahl Salt-Sensitive Rat Model of Chronic Kidney Disease
Authors: Sood Ambika
Published: May 2023

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Glucocorticoid-induced Stress Mechanism in Mouse Primary Neurons
Authors: Prevoznik Stephen
Published: May 2023

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Severe Transaminitis in Allopurinol-Induced DILI presenting as DRESS Syndrome
Authors: Battepati Dhanushya
Published: May 2023

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Use of Endoscopic Vacuum Therapy to Repair Colonic Anastomotic Leaks:
Authors: Farrow David
Published: May 2023

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Bilateral Accessory (Aberrant) Renal Arteries Associated With Uncontrolled Hypertension—Role of Renin-Angiotensin-Aldosterone Antagonist Drugs for Treatment Goal:
Authors: Akpunonu Basil
Published: May 2023

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A Case of Rhabdomyolysis with Rigors
Authors: Akpunonu Basil
Published: May 2023

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Epididymo-orchitis Secondary to Colovesical Fistula
Authors: Waack Andrew
Published: May 2023

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Bictegravir, Emtricitabine & Tenofovir Alafenamide-associated Acute Pancreatitis
Authors: Alharbi Abdulmajeed
Published: May 2023

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Lithium-Induced Nephrogenic Diabetes Insipidus Self-Treated With Beer Potomania and Masquerading as Shock:
Authors: Badal Joyce
Published: May 2023

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Exploring the Accuracy of the Medication Reconciliation Process on the Medical Floor
Authors: Campbell Drew
Published: May 2023

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Are Three Better than Two? –
Authors: Holtzapple Zachary
Published: May 2023

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Clinically Significant Gastrointestinal Bleeding Using Proton Pump Inhibitors or Histamine Type-2 Receptor Antagonists in Patients Intubated for Over 48 Hours:
Authors: Khokher Waleed
Published: May 2023

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Heerfordt-Waldenstrom Syndrome:
Authors: Kloster Alex
Published: May 2023

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The Role of Tranexamic Acid Use in Reducing Mortality in Acute Upper GI Bleeding:
Authors: Sayeh Wasef
Published: May 2023

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A Case of Acute Myopericarditis in a Patient with Human Metapneumovirus (hMPV) Respiratory Infection
Authors: Wang Li
Published: May 2023

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Probing Dynamics of 14-3-3:
Authors: Gurung Deepti
Published: May 2023

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NF1 in Solid Tumors:
Authors: Patel Rayna
Published: May 2023

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A patient with Factor V Leiden mutation who developed a Pulmonary Embolism and Deep Vein Thrombosis post Covid
Authors: Rehman Naveen
Published: May 2023

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Urban-rural Disparities in Trends of Pulmonary Hypertension-Related Mortality in the United States, 2004-2019
Authors: Issa Rochell
Published: May 2023

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Daptomycin Induced Rhabdomyolysis and Subsequent Compartment Syndrome:
Authors: Esser Katherine
Published: May 2023

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Early Infectious Diseases Consultation and Procalcitonin-Guided Therapy Limits Unnecessary Antibiotic Use in COVID-19
Authors: Kammeyer Joel
Published: May 2023

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Pleural plasmacytomas in a Patient with Multiple Myeloma Relapse
Authors: Al-Ataby Harith A.
Published: May 2023

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Spontaneous Second Intercostal Artery Bleeding Complicated with Massive Hemothorax after Lower Limb Angioplasty Procedure
Authors: Al-Ataby Harith
Published: May 2023

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Pulse Versus Nonpulse Steroid Regimens in Patients with Coronavirus Disease 2019:
Authors: Borchers Elizabeth
Published: May 2023

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Reversal of Spironolactone-Induced Gynecomastia:
Authors: Carsel Alex
Published: May 2023

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MAXIMUM SUM ARRAY FIRST SEARCH ALGORITHM FOR GRAPH TRAVERSAL
Authors: C.M.T.Karthigeyan  , C.SatheeshPandian
Published: May 2023

Graphs are the commonly used data structures that describe a set of objects as nodes and the connections between them as edges. Graph traversal is a technique to find all nodes reachable from a given set of root nodes. To traverse a graph is to process every node in the graph exactly once. The two most widely used algorithms used for traversing a graph are Breadth First Search and Depth First Search. This paper presents a new algorithm namely maximum sum array first search algorithm for traversing a graph. In this algorithm the node with the maximum number of edges if processed first and then its neighboring nodes are processed. This paper presents an algorithm to traverse an undirected or a directed graph and calculates the time and space complexity of the algorithm. The objective of proposed algorithm is to find a new alternative algorithm that can be applied to all types of graphs.
Inserción de la mujer al mercado laboral. Empleo de alta dirección en la región central del Estado de Zacatecas 2000-2020
Authors: Ultreras Correa Paulina , Ortiz Medina Imelda , Hernández Ortiz Marlen
Published: May 2023

El objetivo de este libro es mostrar la relación entre la educación superior de las mujeres y el desempeño en un puesto de alta dirección, rescata, además, el feminismo como un movimiento social trascendente en el desarrollo personal de la mujer, así como en su entorno económico. Se observan las principales variables que explican la aceptación o el rechazo de los espacios laborales de alta dirección y, por ende; si estos trabajos reúnen las condiciones ideales para la incorporación y la permanencia de la mujer. En el presente estudio se consideran aquellas mujeres profesionistas que ejerzan puestos de toma de decisiones, de mando, gerenciales o directivos tanto en la esfera pública como en la privada, dentro del sector formal de la economía. Se busca encontrar la relación existente entre la educación superior y el alcance de puestos de poder, identificar en que unidades económicas se desarrollan, estudiar los obstáculos a los cuales se enfrentan para incorporarse en ellos, además de determinar las implicaciones de índole económica, social y familiar que esta incorporación genera en la región zacatecana de estudio. No obstante, de que la mujer pertenece cada día más a un sector activo en la economía, la desigualdad laboral, la discriminación y la brecha salarial siguen estando presentes, aunados a las inequidades laborales que se podrían traducir como un exceso de obligaciones repartidas desproporcionadamente entre las jefas de familia, en donde una de ellas tiende a tener dos o más responsabilidades en el hogar.
Assessing the Learning of Qualitative Research Through a Critical Reflective Essay
Authors: Cena Elida , Burns Stephanie
Published: May 2023

Despite a longstanding commitment to the notion of reflection as an integral part of qualitative research, there are few explicit learning tools or published assignment guides to aid understanding of this important aspect of student learning. Reflection both as a researcher and within the context of an educational perspective can be challenging; however, creating reflective assignments can help students consolidate and assess the learning of qualitative research skills in practice. This article describes a critical reflective assignment highlighting the challenges, rewards, and reflections on designing and conducting an interview process as part of a qualitative research methods module with postgraduate psychology students. We also consider the evaluations students have provided for this assignment and our reflections on what can be improved in the future.
Energy Dynamics in Chronic Heart Failure, Chronic Kidney Disease & the Cardiorenal Syndrome: A New Causal Paradigm
Authors:   Department of Radiology, Sparrow Health System, Lansing, MI, Thorp K. E. , Thorp James A. ,   Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Sisters of St. Mary’s Health System, St. Louis, MO, Northrup Christiane ,   Former Assistant Professor Obstetrics and Gynecology, Vermont College of Medicine, Maine Medical Center, Yarmouth, ME 04096, Thorp Elise M. ,   BS FNTP. Williamston, MI, Scott-Emuakpor Ajovi ,   Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, East Lansing, MI  48823, Kepros John P. ,   Trauma Health Director, Honor Health System, Scottsdale, AZ
Published: May 2023

In this paper we examine HF and CKD through the lens of a new causal paradigm: as a conjoined energy deficiency syndrome whose progression is governed by impaired energy generation by the cardiovascular system leading to subsequent deterioration of blood energy dynamics. Due to the immense complexity of this topic our intention is not to go into unnecessary and laborious detail on specific cellular and molecular aspects of the syndromes but, instead, to use illustrative examples to establish overarching principles and to highlight the connection between the deteriorating energy field and all resultant aberrations. Indeed, once the energy dynamics are recognized cellular and molecular descriptions become superfluous. Our use of the term 'causal' is meant to imply that future breakthroughs in the treatment (and potential reversal) of these complex disease states necessarily entails recognition and correction of underlying energy deficits.