bluuebunny/crossref_metadata_2025 huggingface dataset:
Diseño de un instrumento para la evaluación de la alfabetización mediática en adolescentes
Authors: Valle-Razo Ana Luisa , Torres-Toukoumidis Ángel , Romero-Rodríguez Luis M.
Published: February 2020

La presente investigación ilustra el proceso de realización e implementación de un cuestionario de 42 preguntas que permite conocer el nivel de alfabetización mediática en adolescentes. Fue diseñado a partir de la categorización de los indicadores pertenecientes a cada una de las seis dimensiones de la competencia mediática propuestos por Ferrés y Piscitelli (2012) a través del uso de referentes audiovisuales contemporáneos. La implementación de esta herramienta evidenció un déficit en el dominio de las habilidades funcionales y analíticas que supone esta formación en los 63 sujetos que conformaron la muestra de investigación, además existió una brecha de género al ser las mujeres quienes mayor puntaje obtuvieron. Asimismo, se encontró un aumento casi progresivo del promedio obtenido en función del incremento de edad. La creación de este instrumento pretende abonar a la corriente de estudios que evalúan las habilidades necesarias para relacionarse con y a partir de los nuevos medios de comunicación.
Prototype test study on dynamic stress of utility tunnel under traffic load
Authors: Jiang Lianzi , Xie Zhongqiu , Huang Yi
Published: February 2020

In order to ensure the safety of utility tunnel, the response of each measuring point of the utility tunnel at different speeds is analyzed under the condition that half of the vehicle body is within the boundary of the utility tunnel. The influence of different speeds on the structure of the utility tunnel under the same working condition is discussed, and the dynamic stress variation law of the utility tunnel under actual traffic load is analyzed. The results show that the influence of vehicle speed on the left wall and axillary of the longitudinal utility tunnel is greater than that of the cross-section. The peak values of transverse tensile stress and compressive stress of the right side wall are the largest. The peak transverse stress of the left wall is only 1/3 of that of the right wall. The peak value of the longitudinal compressive stress of the left wall is the largest. The peak value of longitudinal tensile stress of roof is the largest. In the design and construction, the weak position should be reinforced.
A new fault diagnosis method using deep belief network and compressive sensing
Authors: Ma Yunfei , Jia Xisheng , Bai Huajun , Wang Guanglong , Liu Guozeng , Guo Chiming
Published: February 2020

Compressive sensing provides a new idea for machinery monitoring, which greatly reduces the burden on data transmission. After that, the compressed signal will be used for fault diagnosis by feature extraction and fault classification. However, traditional fault diagnosis heavily depends on the prior knowledge and requires a signal reconstruction which will cost great time consumption. For this problem, a deep belief network (DBN) is used here for fault detection directly on compressed signal. This is the first time DBN is combined with the compressive sensing. The PCA analysis shows that DBN has successfully separated different features. The DBN method which is tested on compressed gearbox signal, achieves 92.5 % accuracy for 25 % compressed signal. We compare the DBN on both compressed and reconstructed signal, and find that the DBN using compressed signal not only achieves better accuracies, but also costs less time when compression ratio is less than 0.35. Moreover, the results have been compared with other classification methods.
Ripening of household slow sand filter by adding fish food
Authors: Calixto Kalyl Gomes , Sabogal-Paz Lyda Patricia , Pozzi Eloisa , Campos Luiza Cintra
Published: February 2020

Vulnerable communities can improve their quality of life using point-of-use water treatment technologies. Among these technologies, household slow sand filters (HSSF), which are filters adapted to domestic operations, stand out as one of the most effective and sustainable alternatives. However, some technical issues are not fully understood, such as the ripening process, which may take a long time to take place. In this context, this research evaluated the performance of a HSSF, in real scale and operated in continuous flow when a source of nutrients (fish food) was added to influent water, as a potential ripening agent. Physicochemical and microbiological parameters were evaluated to estimate the filter efficiency. According to the results, the HSSF reached a partial ripeness level in a short time with target parameter reduction in filtered water. Nevertheless, the instability observed in the filtered water quality reveals the significant health risks associated with human consumption when the HSSF is not yet ripened.
Artificial Neural Network Models for Coronary Artery Disease
Authors: Shamsara Elham , Soflaei Sara Saffar , Tajfard Mohammad , Yamshchikov Ivan , Esmaily Habibollah , Saberi-Karimian Maryam , Ghazizadeh Hamideh , Mirhafez Seyed Reza , Farjami Zahra , Ferns Gordon A. , Ghayour-Mobarhan Majid
Published: February 2020

Background:

Coronary artery disease (CAD) is an important cause of mortality and
morbidity globally.

Objective :

The early prediction of the CAD would be valuable in identifying individuals at risk,
and in focusing resources on its prevention. In this paper, we aimed to establish a diagnostic model
to predict CAD by using three approaches of ANN (pattern recognition-ANN, LVQ-ANN, and
competitive ANN).

Methods:

One promising method for early prediction of disease based on risk factors is machine
learning. Among different machine learning algorithms, the artificial neural network (ANN)
algorithms have been applied widely in medicine and a variety of real-world classifications. ANN
is a non-linear computational model that is inspired by the human brain to analyze and process
complex datasets.

Results:

Different methods of ANN that are investigated in this paper indicate in both pattern
recognition ANN and LVQ-ANN methods, the predictions of Angiography+ class have high
accuracy. Moreover, in CNN, the correlations between the individuals in cluster ”c” with the class
of Angiography+ are strongly high. This accuracy indicates the significant difference among some
of the input features in Angiography+ class and the other two output classes. A comparison among
the chosen weights in these three methods in separating control class and Angiography+ shows that
hs-CRP, FSG, and WBC are the most substantial excitatory weights in recognizing the
Angiography+ individuals although, HDL-C and MCH are determined as inhibitory weights.
Furthermore, the effect of decomposition of a multi-class problem to a set of binary classes and
random sampling on the accuracy of the diagnostic model is investigated.

Conclusion:

This study confirms that pattern recognition-ANN had the most accuracy of
performance among different methods of ANN. This is due to the back-propagation procedure in
which the network classifies input variables based on labeled classes. The results of binarization
show that decomposition of the multi-class set to binary sets could achieve higher accuracy.
Scopolamine, a Toxin-Induced Experimental Model, Used for Research in Alzheimer’s Disease
Authors: Chen Win Ning , Yeong Keng Yoon
Published: February 2020

Scopolamine as a drug is often used to treat motion sickness. Derivatives of scopolamine
have also found applications as antispasmodic drugs among others. In neuroscience-related research, it
is often used to induce cognitive disorders in experimental models as it readily permeates the bloodbrain
barrier. In the context of Alzheimer’s disease, its effects include causing cholinergic dysfunction
and increasing amyloid-β deposition, both of which are hallmarks of the disease. Hence, the application
of scopolamine in Alzheimer’s disease research is proven pivotal but seldom discussed. In this review,
the relationship between scopolamine and Alzheimer’s disease will be delineated through an
overall effect of scopolamine administration and its specific mechanisms of action, discussing mainly
its influences on cholinergic function and amyloid cascade. The validity of scopolamine as a model of
cognitive impairment or neurotoxin model will also be discussed in terms of advantages and limitations
with future insights.
Sophoricoside: Bioactive Compounds from Sophora japonica, their Role in Disease Prevention and Treatment
Authors: Patel Kanika , Husain Gulam Mohammed , Katiyar Devendra Kumar , Prasad Satyendra K. , Patel Dinesh Kumar
Published: February 2020

Herbal drugs and their derived products play an important role in human life due
to their defensive nature against various diseases. The demand of herbal based products is
continuously increasing in society due to their less toxicity and more value for health. Pure
phytochemicals of plants have been placed in modern medicine due to their healthpromoting
aspects as we know that some of the important modern medicines contain pure
active chemicals obtained from plants, minerals and organic matter. A large number of drugs
prescribed in modern medicine are derived from plants. Phytochemicals are present in various
herbs, fruits, vegetables, oils, and seeds. Sophora japonica is a tree native to China and
Korea also called a Japanese pagoda tree or Chinese scholar tree. Sophoricoside is an isoflavone
glycoside present in the Sophora japonica plant. Sophoricoside has been known for its
estrogenic activity, anti-inflammatory, anti-oxidant, anti-diabetic and immunomodulatory activity.
In the present review paper, we have collected all the information of sophoricoside
and summarized its pharmacological activities, pharmacokinetics, analytical techniques and
biotransformation method in a very concise manner. This article aims at providing an overview
of the pharmacological effects of sophoricoside and its mechanisms of actions in various
diseases. Databases namely Medline, PubMed, Google and Science direct were searched
to collect the data for this review. The present review will be helpful to the scientists of the
Botanical, Medicinal and Pharmaceutical field for the discovery and development of new
novel medicines from sophoricoside.
Green Synthesis of ZnO/Dy/NiO Heterostructures for Enhanced Photocatalytic Applications
Authors: Pranesh Shubha Jayachamarajapura , Lanka Diwya
Published: February 2020

Background:

Textile industries discharge harmful synthetic dyes to nearby water sources. These
colour effluents should be treated before discharge to reduce the toxicity caused by synthetic colours.

Objective:

To synthesize visible light active superstructures to reduce water pollution caused by textile industries.

Methods:

We have successfully synthesized ZnO/Dy/NiO hybrid nanocomposites using waste curd as fuel
by a simple combustion method. The obtained material was able to reduce recombination and enhanced the
photocatalytic degradation of organic pollutants. The as-synthesized material was characterized by XRD,
absorption spectroscopy, FESEM, EDAX, etc. The obtained hybrid nanostructure was used as a photocatalyst
for the degradation of methylene blue under sunlight, UV light as well as in dark. Comparative experiments
were carried out with a variation of catalytic load, pH, dye concentrations, etc. for a better understanding
of the performance of the catalyst at various conditions.

Results and Conclusion:

The ternary compound shows wide range of absorption by expanding absorption
band both in UV and visible regions. ZnO/Dy/NiO hybrid nanocomposites performed well and showed
uniqueness in the activity uder visible light.
Kerapatan Fasilitas Kesehatan Tingkat 1 berdasarkan Permasalahan Kesehatan Gigi dan Mulut di Provinsi Daerah Istimewa Yogyakarta
Authors: Tandelilin Regina Titi Christinawati , Setiawan Prayudha Benni , Mugiwardani Anggita
Published: February 2020

Latar belakang: Fasilitas kesehatan merupakan suatu alat atau tempat yang digunakan untuk menyelenggarakan upaya pelayanan kesehatan. Pemetaan fasilitas kesehatan di Provinsi Daerah Istimewa Yogyakarta menggunakan Sistem Informasi Geografis diperlukan karena keberhasilan penanggulangan permasalahan kesehatan gigi dan mulut masyarakat dipengaruhi oleh ketersediaan fasilitas kesehatan.Tujuan: Tujuan dari penelitian ini adalah menggambarkan pemetaan permasalahan kesehatan gigi dan mulut berdasarkan fasilitas kesehatan tingkat 1 di Provinsi Daerah Istimewa Yogyakarta berbasis software ArcGIS 9.3.Metode: Penelitian ini merupakan penelitian deskriptif menggunakan Sistem Informasi Geografi (SIG) untuk melihat persebaran permasalahan kesehatan gigi dan mulut berdasarkan fasilitas kesehatan tingkat 1 di Provinsi Daerah Istimewa Yogyakarta. Penelitian dilakukan di lima kabupaten/kota di Provinsi Daerah Istimewa Yogyakarta menggunakan data jumlah penduduk dari BPS dan data permasalahan gigi dan mulut dari Riskesdas tahun 2007 dan 2013.Hasil: Hasil penelitian menunjukkan bahwa pada tahun 2013 dilakukan penambahan unit puskesmas dari 90 unit menjadi 121 unit pada tahun 2013. Persentase masalah kesehatan gigi dan mulut juga meningkat dari 30,7% menjadi 40,4%. Tetapi, kebiasaan menyikat gigi yang benar pada masyarakat justru mengalami penurunan dari 97,3% menjadi 78,6%.Kesimpulan: densitas fasilitas kesehatan puskesmas di Provinsi Daerah Istimewa Yogyakarta pada tahun 2013 lebih baik dibandingkan dengan tahun 2007, tetapi dari segi kualitas kesehatan masyarakat pada tahun 2013 mengalami penurunan dibandingkan dengan tahun 2007.
Documentos orales y escritos en la preservación de la memoria escolar
Authors: Odetti Cecilia Ángela , Magalhães Lívia Diana Rocha
Published: February 2020

Resumen

En este artículo se analizan los documentos orales y escritos como formas de preservar la memoria escolar. Desde esta perspectiva se conceptualiza acerca de la memoria como documento-huella, como fuente de expresión de un tiempo y de una realidad, de una sociedad, de grupos y colectivos educacionales y, por lo tanto, genera marcas que estructuran relaciones sociales y pedagógicas, al mismo tiempo que dejan pistas en los procesos de reconstrucción de los sentidos atribuidos a la escuela en el presente y futuro. Además, se retoman orientaciones teórico-metodológicas que fueron utilizadas para el análisis de los documentos y definiciones necesarias en el tratamiento y construcción de los mismos durante un proceso de investigación. Para finalizar, se concluye que los documentos orales y escritos son indispensables para la preservación de la memoria escolar en tanto permiten analizar sus tensiones y continuidades, instancia que supone comprender quienes son los sujetos que hablan y cómo vinculan sus posicionamientos en núcleos significativos a través del tiempo.

Palabras clave: Memoria escolar. Documentos orales y escritos.

 

Resumo

Neste artigo, os documentos orais e escritos são analisados como formas de preservar a memória escolar. Nessa perspectiva, utiliza-se da discussão teórica acerca da memória como documento, como fonte de expressão de um tempo e de uma realidade, de uma sociedade, de grupos e coletivos educacionais, e que, portanto, é geradora de marcas que estruturam relações sociais e pedagógicas, deixando pistas para os processos de reconstrução de sentidos atribuídos à escola ontem, no presente e futuro. Também se retoma diretrizes teórico-metodológicas que foram utilizadas para análise dos documentos, para seu tratamento, enfim, o percurso adotado durante o processo de pesquisa. Por fim, considera-se documentos orais e escritos são essenciais para a discussão da memória escolar, pois permitem analisar suas tensões e continuidades, instância que envolve entender quem são os sujeitos que falam e como vinculam suas posições em núcleos significativos ao longo do tempo.

Palavras-chave: Memoria escolar. Documentos orais e escritos.
The Relationship between Self-efficacy and Learning Environment with Students' Self-directed Learning
Authors: Mirzawati Nanda , Neviyarni Neviyarni , Rusdinal Rusdinal
Published: February 2020

The lack of self-directed learning of students shown by students is one problem associated with self-efficacy and the learning environment. The purpose of the research is to reveal the relationship between self-efficacy and the learning environment, and self-directed learning. This study uses the correlational method and data collected from a sample of 198 students, which were found using proportional random sampling techniques. Data were collected using a self efficacy scale (24 valid items = 0.851), a learning environment scale (32 valid items = 0.830), and a self-directed learning scale (64 valid items = 0.936). Data were then analyzed using multiple regression. The results showed the correlation coefficient r = 0.535 and p = 0.00 (p> 0.05), which showed that there was a positive and significant relationship between self-efficacy and the learning environment together with self-directed learning. So it can be explained that the higher the self-efficacy and learning environment, the higher the student's self-directed learning.
Insignificant Relationship Between Speaking Self-Efficacy and Language Learning Anxiety of English Department Students at The University of Riau, Indonesia
Authors: Hadriana
Published: February 2020

Many studies have delved into the connection between self-efficacy and language anxiety. However, the findings are somewhat inconsistent: self-efficacy has either positive, negative or no relationship at all with language anxiety. Therefore, this research aims to examine the relationship between students’ self-efficacy and language anxiety in learning speaking in EFL classroom. The subjects of this study were second-year English Department students at the University of Riau, Indonesia taking Speaking subject (N = 40). Data on their self-efficacy and language anxiety were collected through the questionnaire. The data analysis results reveal that the students have very good self-efficacy in speaking. They also show a moderate level of anxiety. However, statistical analysis reveals that there is no relationship between the two variables. Despite the limited number of participant, this finding is expected to shed a light on the contribution of self-efficacy and anxiety on learning speaking in EFL context. This finding suggests that although the self-efficacy and anxiety levels were similar with previous studies, there might be different patterns of relationship between these variables depending on the context. This implies that teachers should be aware of this before taking any measure to improve students speaking skills.
The Influence of Thermal Processing on Antioxidant Capacity of Tomatoes Based Products
Authors: Florica Buşuricu , Andreea Anghel , Doina Margaritti , Sirma Tomoş , Verginica Schroder
Published: February 2020

We intend to study the influence of thermal processing on the antioxidant capacity of tomato products. The products were analyzed for lycopene content and antioxidant activity. Lycopene was extracted using a mixture of hexane: ethyl alcohol: acetone, in ration of 1:25 (w: v). The antioxidant capacity was evaluated by the DPPH method. The obtained results show a higher quantity of lycopene in the processed products (8, 4800 ±0, 48079 - 11,8217 ±0. 37010 mg/100g), compared to the fresh ones (2.9400±0.1510-4.0933±0.16773 mg/100g) and the antioxidant activity registers higher values in the aqueous extracts (21-45%).

The thermal processing concentrates the content of lycopene and preserves the antioxidant activity, so that for the optimal nutritional intake of antioxidant phytonutrients, the consumption of processed tomatoes is indicated, to the detriment of the fresh tomatoes.
Economic freedom in Europe
Authors: Apostu Simona-Andreea , Mihai Mihaela , Vasile Valentina , Tureatca Manuela-Violeta , Sava Valentin
Published: February 2020

The fiscal analysis is an important research topic, aiming at identifying/creating fair fiscal systems, which can respond to requests coming from both the state (which needs revenue to finance various public projects) and from taxpayers. The economic agents, but also the taxpayers will always want a reduction of the taxes, and the public decider aims to increase the revenues attracted to the budget through (higher) taxes. An optimal tax system could be characterized by taxes that produce minimal effects of distorting the behavior of taxpayers, as well as a positive impact on the development of society.
Voluntary employee attrition. Descriptive and predictive analysis
Authors: Căplescu Raluca-Dana , Ilie Miruna , Strat Vasile Alecsandru
Published: February 2020

Voluntary attrition represents the percent of employees voluntarily leaving a company. Counteracting this phenomenon with hiring new employees has a great negative impact on the company for several reasons. Firstly, it hinders timely delivery of current projects and, consequently, damages reputation and diminishes client portfolio. Secondly, it increases costs by generating the need for many recruitment specialists. Thus, adapting the HR strategy is essential, especially as increasingly more Millennials enter the labor market. The present paper aims at presenting options for studying voluntary attrition and the situations when they can be used. We indicate both descriptive methods (turnover and retention rates, cohort analysis), in order to present tools that any HR manager can easily employ, and predictive methods (logistic regression, survival analysis), which are more accurate and provide more actionable insight towards minimizing attrition, but require data and skills. The results are presented comparatively, highlighting the advantages and disadvantages of each category. Most literature focuses on a single method, thus the main contribution of this article is that it compares several methods, allowing for an informed decision of the HR specialist, depending on the company’s resources, personnel qualification and specific context.
The economic impact of migration in the Era of Globalization
Authors: Lupoiu Diana Valentina , Raceanu Cristi
Published: February 2020

The phenomenon of globalization has greatly influenced migration in recent years in the European Union. In this article we aim to analyze the benefits of migration in the economy by emphasizing the impact of remittances on the economic development of a country. Remittances are considered as an external source of important, stable funds that help the economic development of a country. We identify also the macroeconomic determinants of remittances. For the statistical and econometric analysis of these factors, we have chosen to use the Panel Data Regression for the countries of the European Union. To analyze the benefits of remittances, the most appropriate macroeconomic indicator is GDP. So in the first part of the article we will present the impact of globalization and migration on remittances, and in the second part we will highlight the economic growth through the presence of remittances. This article examines the role of migrants as a particular segment of the market and as a resource for development. All aspects to be analyzed will outline an overview of population emigration and factors that influence the development of the economy at a time when globalization is on the rise.
Statistical analysis of investments in transport infrastructure, passenger numbers, and energy consumption by modes of transport in Romania
Authors: Stătescu Alexandru-Eugen
Published: February 2020

Economic and financial analysis is a method of knowing the mechanism of formation and modification of the economic phenomena by their decomposition into the component elements and by identifying the factors of influence. The object of decomposition by elements or factors may be a result (structural analysis), or a change in the result from a basis of comparison (causal analysis).

In the present paper I propose an analysis of the investments according to the number of passengers and the consumption of energy on national transport modes in Romania within a period of 15 years, respectively between 2000 and 2015. For this purpose the data that will be used was published by the National Institute of Statistics, namely three indicators: investments in transport infrastructure, the weight of each mode in passenger transport and the consumption of energy by modes of transport. Energy consumption by modes of transport is the final energy consumption of transport activity by modes of transport, expressed in tones oil equivalent (toe). The quantities of energy used in international maritime and air transport and pipeline transport are not included. The main types of fuels used are the main fuels covered by petroleum products, electricity and small amounts of gas and biofuels.

The weight of each mode in passenger transport is defined as the percentage share of each mode of transport in total domestic passenger transport. The modes of transport considered are: a) cars, b) buses and coaches, and c) trains (metro and trams and light metro are excluded). Domestic passenger transport includes data referring only to national transport, irrespective of the nationality of the transport vehicle. The weight is calculated from the passenger-km indicator (pkm), defined as the transport of a passenger over one kilometer.

The investments in the transport infrastructure represent the construction works carried out for the development of the transport infrastructure.

In order to carry out the statistical analysis of the investments in the transport infrastructure, the number of passengers and the energy consumption in transport modes in Romania, multiple linear regression models and time series analysis will be used.
Cerebellar Haemorrhage Leading to Sudden Cardiac Arrest
Authors: Agrawal Ankit , Cardinale Maria , Frenia Douglas , Mukherjee Aveek
Published: February 2020

Introduction

Intracranial haemorrhage (ICH) is a known, but a rare cause of out of hospital cardiac arrest (OHCA). It results in the development of non-shockable rhythms such as asystole or pulseless electrical activity (PEA).

Case Report

A 77- years old male had an OHCA without any prodrome. An emergency medical services (EMS) team responded to an emergency call and intubated the patient at the site before transporting him to the Acute Care Hospital, New Brunswick, New Jersey, USA. On admission, a non-contrast computed tomography scan of the head revealed a large cerebellar haemorrhage. Non-traumatic ICH is a rare cause of OHCA. Although subarachnoid haemorrhage causing cardiac arrest has been described in the literature, cerebellar haemorrhage leading to cardiac arrest is rare. The mechanism by which ICH patients develop cardiac arrest is likely explained by a massive catecholamine surge leading to cardiac stunning.

Conclusion

A non-shockable rhythm in the seting of a sudden cardiac arrest should raise alarms for a primary non-cardiac ethology, especially a primary cerebrovascular event. The absence of brainstem reflexes increases the likelihood of an intracranial process.
Guillain–Barré and Acute Transverse Myelitis Overlap Syndrome Following Obstetric Surgery
Authors: Stoian Adina , Motataianu Anca , Bajko Zoltan , Balasa Adrian
Published: February 2020

Introduction

There are rare reports of the occurrence of acute transverse myelitis and Guillain–Barré syndrome after various surgical procedures and general/epidural anaesthesia. The concomitant occurrence of these pathologies is very rare and is called Guillain–Barré and acute transverse myelitis overlap syndrome. In this article, we present the case of a second trimester pregnant patient who developed Guillain–Barré and acute transverse myelitis overlap syndrome.

Case presentation

We report the case of a 16-year-old female patient who underwent a therapeutic termination of pregnancy two weeks prior to the onset of the disease with gradual development of a motor deficit with walking and sensitivity disorders, fecal incontinence. The diagnosis was based on clinical exam, electroneurography and spinal magnetic resonance imaging. Endocrinopathies, infectious diseases, autoimmune and inflammatory diseases, neoplastic diseases and vitamin deficiencies were ruled out. Our patient attended five sessions of therapeutic plasma exchange, followed by steroid treatment, intravenous immunoglobulin with minimum recovery of the motor deficit in the upper limbs, but without significant evolution of the motor deficit in the lower limbs. The patient was discharged on maintenance corticotherapy and immunosuppressive treatment with azathioprine.

Conclusions

We report a very rare association between Guillain–Barré syndrome and acute transverse myelitis triggered by a surgical intervention with general anaesthesia. The overlap of Guillain–Barré syndrome and acute transverse myelitis makes the prognosis for recovery worse, and further studies are needed to establish the first-line therapy in these cases.
Concentration distribution and deposition limit of medium-coarse sand-water slurry in inclined pipe
Authors: Vlasák Pavel , Matoušek Václav , Chára Zdeněk , Krupička Jan , Konfršt Jiří , Kesely Mikoláš
Published: February 2020

Sand-water slurry was investigated on an experimental pipe loop of inner diameter D = 100 mm with the horizontal, inclined, and vertical smooth pipe sections. A narrow particle size distribution silica sand of mean diameter 0.87 mm was used. The experimental investigation focused on the effects of pipe inclination, overall slurry concentration, and mean velocity on concentration distribution and deposition limit velocity. The measured concentration profiles showed different degrees of stratification for the positive and negative pipe inclinations. The degree of stratification depended on the pipe inclination and on overall slurry concentration and velocity. The ascending flow was less stratified than the corresponding descending flow, the difference increasing from horizontal flow up to an inclination angle of about +30°. The deposition limit velocity was sensitive to the pipe inclination, reaching higher values in the ascending than in the horizontal pipe. The maximum deposition limit value was reached for an inclination angle of about +25°, and the limit remained practically constant in value, about 1.25 times higher than that in the horizontal pipe. Conversely, in the descending pipe, the deposition limit decreased significantly with the negative slopes and tended to be zero for an inclination angle of about −30°, where no stationary bed was observed.
Ski piste snow ablation versus potential infiltration (Veporic Unit, Western Carpathians)
Authors: Mikloš Michal , Igaz Dušan , Šinka Karol , Škvareninová Jana , Jančo Martin , Vyskot Ilja , Škvarenina Jaroslav
Published: February 2020

Snow production results in high volume of snow that is remaining on the low-elevation ski pistes after snowmelt of natural snow on the off-piste sites. The aim of this study was to identify snow/ice depth, snow density, and snow water equivalent of remaining ski piste snowpack to calculate and to compare snow ablation water volume with potential infiltration on the ski piste area at South-Central Slovak ski center Košútka (Inner Western Carpathians; temperate zone). Snow ablation water volume was calculated from manual snow depth and density measurements, which were performed at the end of five winter seasons 2010–2011 to 2015–2016, except for season 2013–2014. The laser diffraction analyzes were carried out to identify soil grain size and subsequently the hydraulic conductivity of soil to calculate the infiltration. The average rate of water movement through soil was seven times as high as five seasons’ average ablation rate of ski piste snowpack; nevertheless, the ski piste area was potentially able to infiltrate only 47% of snow ablation water volume on average. Limitation for infiltration was frozen soil and ice layers below the ski piste snowpack and low snow-free area at the beginning of the studied ablation period.
Are coastal deserts necessarily dew deserts? An example from the Tabernas Desert
Authors: Kidron Giora J. , Lázaro Roberto
Published: February 2020

Vapor condensation, whether due to dew or fog, may add a stable and important source of water to deserts. This was also extensively assessed in the Negev, regarded as a dew desert. Dew deserts necessitate a large reservoir of vapor, and are therefore confined to near oceans or seas. Yet, examples of such deserts are scarce. Here we try to assess whether the Tabernas Desert in SE Spain can be regarded as a dew desert, and may therefore facilitate the growth of certain organisms that otherwise would not survive the dry season. We analyze some of the abiotic conditions of four relatively dry months (June, July, August, September) in the Tabernas and Negev deserts (with the Negev taken as an example of a dew desert) during 2003–2012. The analysis showed substantially lower values of relative humidity (by 10–13%) in the Tabernas in comparison to the Negev, with RH ≥95% being on average only 0.9–1.1 days a month in the Tabernas in comparison to 9.7–13.9 days in the Negev. Our findings imply that the Tabernas Desert cannot be regarded as a dew desert, suggesting that rain will be the main factor responsible for the food web chain in the Tabernas.
Presence and upregulation of Transient Receptor Potential Vanilloid 1 (TRPV1) and Ankyrin 1 (TRPA1) in translational rat endometriosis model
Authors: Krisztina Pohóczky , Noémi Bohonyi , Péter Maczkó , Béla Kajtár , Zsuzsanna Helyes
Published: February 2020

The Transient Receptor Potential Vanilloid 1 (TRPV1) and Ankyrin 1 (TRPA1) are non-selective cation channels predominantly localized on capsaicin-sensitive sensory neurons; however both receptors have been described in non-neuronal tissues. It has been published that both receptors upregulated in peritoneal endometriosis in humans. Our research group demonstrated that TRPA1 and TRPV1 expression is elevated in human deep infiltrating endometriosis (DIE) lesions and the receptors have an estrogen-dependent expression pattern in rat endometrium. Here, we investigated the expression changes of TRPA1/V1 and the role of the capsaicin-sensitive sensory-nerve endings in a rat model of peritoneal endometriosis. Peritoneal endometriosis was surgically induced in 8-week-old female rats (n=7-7) for 2-weeks (acute condition) and 8-weeks (chronic condition). TRPA1/V1 mRNAs were quantified with quantitative polymerase chain reaction (qPCR). The expression levels were compared with the results obtained earlier from human DIE samples. The blockade of the TRPA1/V1 expressing capsaicin-sensitive nerve endings was induced with resiniferatoxin (RTX), followed by the measurement of the weight and size of the endometriosis lesions. We detected TRPV1 and TRPA1 mRNA in normal rat endometrium, their expression was not altered in sham-operated animals. In chronic, but not in acute endometriosis the expression was significantly elevated in the lesions, which results are consistent with our previous findings in human DIE. The elimination of capsaicin-sensitive nerve endings decreased the weight of the endometriosis lesions while the size of the ectopic tissue was not altered. Taken together, our results obtained from the rat endometriosis model are consistent with the previous human results, therefore this model is considered to have translational significance and it is suitable for functional analysis of the ion channels. The local, non-neuronal TRPA1 and TRPV1 might play a role in inflammation and sensory neuronal activation in endometriosis related pain, which is mediated by a broad range of pro-inflammatory molecules.
The Uncertain Revival of Central Europe – Central European Thought from a Hungarian Perspective
Authors: Schmidt Andrea
Published: February 2020

The recent crisis that, the European Union has had to face certainly raises questions about the current state of Europe. The question about the legacy of regional integration; the debate between the standpoints about the vision on the European Union with the necessity of strong nations or on the contrary, the opportunity of deepening the cohesion that could lead to the united states of europe; in other words, political integration, the deepest step of regional integration. the paper deals with the problem of the concept on central europe from the standpoint of various concepts; the question of mapping, the meaning of borders, the ways of identification appear in this paper. the difference between the concept of mittel europe and central europe also appear in the paper. analysing the question of central europe it is also inevitable to examine the meaning of central europe from historical context. after the end of the cold war and as the consequence of the euro-atlantic integration, the concept of central europe changed a bit. while during the bipolar system this phenomenon served as a differentiation of the groups of countries being located in the soviet sphere of interest. being central european meant something that was much more engaged with progressive approach in democratization, transformation rather than a sign of nostalgia towards the historical past.
How Does Orthorexia Nervosa Assessment Tools Can Differ – Comparison of Two Questionnaires: BOT and ORTO-15
Authors: Zańko Adrianna , Mielech Anita , Plyton Tapakron , Anud Suheyb , Smarkusz-Zarzecka Joanna , Pietraszewska Barbara , Milewski Robert
Published: February 2020

The paper presents a comparison of the two most commonly used diagnostic tests for orthorexia – ORTO-15 Questionnaire and BOT (Bratman Orthorexia Test) – that use data-mining methods. Orthorexia nervosa is perceived as a new, unclassified eating disorder, which is characterized with pathological fixation on the consumption of healthy foods. In order to assess the coherence of the aforementioned tests, a method from the data-mining group, i.e. correspondence analysis, was used in addition to traditional statistical methods. On the basis of the obtained results, only average correlation between ORTO-15 Questionnaire and BOT test was found. More cases of orthorexia were diagnosed with the use of ORTO-15 Questionnaire, which may result from its higher sensitivity. It was also noted that the coherence of tests increases with increasing BMI values, despite no relationship between BMI and the presence of orthorexia having been proved. Diagnosis of an orthorexia case with the use of BOT test implies that there is a high probability that it will also be diagnosed with the use of ORTO-15 test, but not necessarily the other way around. The performed correspondence analysis confirmed a not very strong coherence of the results of both tests.
Students’ Attitudes towards the Effectiveness of Moodle Platform at Preclinical-Medical Level in PBL Curriculum
Authors: Peerapolchaikul Teeranai , Suealek Nuchanart , Rojpibulstit Panadda
Published: February 2020

Moodle is applied as an online learning management system in the Faculty of Medicine, Thammasat University (TU), where the curriculum has been based on problem-based learning (PBL) since 2015. Little research on the effectiveness of Moodle and students’ attitudes during their studies at the pre-clinical medical level within a PBL curriculum has been conducted. Hence, this cross-sectional study focuses on second- and the third-year (MD-2 and MD-3) preclinical medical students’ attitudes towards Moodle and its effectiveness in the PBL curriculum by using a 27-itemed self-constructed online questionnaire. Additionally, students’ preferences as regards the materials managed by the Moodle platform were also evaluated as students’ preferred behaving style (SPBS). After obtaining ethical approval from the Human Ethics Committee of TU No. 1 (Faculty of Medicine), the data was collected and analyzed by medians and inter-quartile ranges, Mann-Whitney U test, and Spearman correlation (ρ). After analyzing the data, the results indicated the following: (1) the top four attitudes scores, (2) the two lowest-attitude scores, (3) the top five effectiveness scores (Ef), (4) the three lowest effectiveness scores, and (5) the top three SPBS scores. Interestingly, a stronger positive Spearman’s correlation (ρ) between ‘Prefer doing quizzes in Moodle to in classroom’ and ‘Moodle enhances learning capability’ was found for MD-3 compared with MD-2. This study reports that Moodle is preferable as a platform supporting students’ self-learning within a PBL curriculum. However, to use the Moodle platform to the highest benefit, instructors need to upgrade its capabilities, especially in the area of student-teacher interaction and the enhancement of students’ critical thinking and creativity, as demonstrated by the lowest scores obtained in this study.
SAVREMENA TEHNOLOGIJA ODLAGANJA SEDIMENTA NA PRIMERU PLOVNOG BEGEJA
Authors: Radanović Tamara , Mučenski Vladimir
Published: February 2020

Predmet ovog rada je analiza načina izmuljenja Kanala Begej na području Republike Srbije. Radom se porede dve metode za izmuljenje kanala, i definiše ona koja je povoljnija na funkcionalnom, teh­ničkom i ekonomskom nivou.
PROJEKAT FUNDIRANJA VIŠESPRATNE ZGRADE I ANALIZA INTERAKCIJE TEMELJNE PLOČE I TLA
Authors: Mihajlović Stefan
Published: February 2020

U radu je obrađeno projektno rešenje armirano-betonske temeljne ploče zgrade spratnosti Po+P+6 sa posebnim osvrtom na analizu interakcije temeljne ploče i tla. Analiza svih relevantnih opterećenja koja deluju na konstrukciju i dimenzionisanje karakteris­tičnih armiranobetonskih elemenata je razmatrano prema Evrokodovima. Za proračun konstrukcije korišćen je soft­verski paket Tower 8.
MIKROMREŽA TUNELA "STRAŽEVICA" U RESNIKU (BEOGRAD)
Authors: Isailović Slobodan
Published: February 2020

Tunel je najčešće saobraćajni ili hidrotehnički objekat koji se nalazi u zemljištu, na jednom ili oba kraja izlazi na površinu, ili uopšte ne izlazi na površinu. U radu je opisan projekat i realizacija projekta mikromreže za tunel "Straževica" u Beogradu.
SIMULACIJA EFEKATA SLEPILA ZA BOJE
Authors: Haška Aleksandra , Trpovski Željen
Published: February 2020

Cilj ovog rada jeste iznalaženje načina za prevazilaženje dishromatopsije i mogućnosti za njeno rano otkrivanje, kao i simulacija samog efekta radi bližeg i boljeg razumevanja kako osobe sa dishromatopsijom zaista vide. U radu je prezentovan način dolaženja do adetvatne simulacije efekata slepila za boje. U prvom delu rada obrađena je anatomija dela ljudskog oka koji je odgovoran za viđenje boja. Za implementaciju simulacije efekata protanopije, deuteranopije i tritanopije neophod­no je izvršiti prelazak iz RGB u LMS prostor boja. Proces prelaska iz jednog prostora boja u drugi zahtevao je ra­zumevanje sve tri vrste nedostatka, kako bi se na podoban način uticalo na odgovarajuće čepiće.
Mechanochemical Synthesis of Mixed Metal, Mixed Linker GlassForming Metal–Organic Frameworks
Authors: Thorne Michael , Rios Laura , Bumstead Alice , Li Shichun , Bennett Thomas
Published: February 2020

Current methodologies to produce glass forming metal–organic frameworks (MOFs) rely on non-scalable solvothermal syntheses which have high energy requirements, relatively low yields and large tetratogenic solvent usage. Here we use a mechanochemical method to produce glass-forming MOFs, ZIF-62 and ZIF-UC-5, in 30 minutes at room temperature, using microlitre quantities of solvent and stoichiometric amounts of organic linkers. This method facilitates the accurate synthesis of ZIF-62 structures containing both Co and Zn, allowing the effect of metal-ion dopant upon melting temperature to be studied for the first time. Further to this, we present variable organic linker ratio series of IF-62 and of ZIF-UC-5. The specific composition of the materials in the series is made possible by the mechanochemical method. We also present a greener solvothermal method to form ZIF-62, which is capable of producing crystalline materials of suffcient quality for single crystal diffraction experiments.
Concise Chemoenzymatic Total Synthesis and Identification of Cellular Targets of Cepafungin I
Authors: Amatuni Alexander , Shuster Anton , Adibekian Alexander , Renata Hans
Published: February 2020

The natural product cepafungin I was recently reported to be one of the most potent covalent inhibitors of the 20S proteasome core particle through a series of in vitro activity assays. Here, we report a short chemoenzymatic total synthesis of cepafungin I featuring the use of a regioselective enzymatic oxidation to prepare a key hydroxylated amino acid building block in a scalable fashion. The strategy developed herein enabled access to a chemoproteomic probe, which in turn revealed the exceptional selectivity and potency of cepafungin I towards the b2 and b5 subunits of the proteasome. Further structure-activity relationship studies suggest the key role of the hydroxyl group in the macrocycle and the identity of the lipid tail in modulating the potency of this natural product family. This study lays the groundwork for further medicinal chemistry exploration to fully realize the anticancer potential of cepafungin I.
Interleukin IL1a and IL6 gene polymorphism: search for association with APOE genotype and clinical course of sporadic Alzheimer’s disease
Authors: Pšemeneckienė G. , Petrikonis K. , Rastenytė D.
Published: February 2020

Background. There is evidence that genetic polymorphisms of important proinflammatory cytokines IL1α and IL6 are associated with the risk of Alzheimer’s disease (AD). In this study, we aimed to evaluate the association of IL1A -889C>T and IL6 -174G>C polymorphisms with the risk of sporadic AD in APOE ε4 carriers and in persons without APOE risk allele. We also investigated the association of IL1A -889C>T and IL6 -174G>C polymorphisms with the rate of AD progression.Materials and methods. The study included 110 patients with sporadic AD and 115 age-and-gender-matched healthy controls (HC) without cognitive decline (Lithuanian population). Genotyping of IL1A -889C>T (rs1800587) and IL6 -174G>C (rs1800795, Intron type) was performed using real-time PCR (RT-PCR).Results. The distribution of IL1A -889C>T genotypes did not differ between APOE ε4 carriers (APOE4+: C/C – 52.9%, C/T – 41.2%, T/T – 5.9%) and APOE negative AD patients (APOE4-: C/C – 55.6%, C/T – 37.0%, T/T – 7.4%; p=0.887). IL6 -174G>C genotype frequencies in APOE4+ (G/G – 11.8%, G/C – 62.7%, C/C – 25.5%) and APOE4- (G/G – 14.8%, G/C – 61.1%, C/C – 24.1%) were also similar (p=0.898) in AD group. No significant differences of genotype frequencies in rapidly progressing AD compared to slowly progressing AD were revealed (p (IL1A -889C>T)=0.638; p (IL6 -174G>C)=0.118). Controlling by APOE4 status, the inheritance of IL1A -889C>T or IL6 -174G>C polymorphisms (dominant, overdominant, and recessive models) did not significantly alter the odds ratio for sporadic AD (p<0.05). In slowly and rapidly progressing AD groups, the inheritance of IL1A -889C>T and IL6 -174G>C polymorphisms had no significant impact on AD risk (p<0.05).Conclusions. No significant differences of IL1A -889C>T and IL6 -174G>C genotype frequencies were found either between groups according to the APOE ε4 allele possession or in patients with rapidly progressing AD compared to slowly progressing AD patients. No significant associations of IL1A -889C>T and IL6 -174G>C polymorphisms and AD risk were revealed in either APOE4 positive or APOE4 negative persons. According to our data, inheritance of IL1A -889C>T and IL6 -174G>C polymorphisms is not associated with faster progression of AD.
Perancangan Alat Monitoring Pendeteksi Suara di Ruangan Bayi RS Vita Insani Berbasis Arduino Menggunakan Buzzer
Authors: Fani Handri Al , Sumarno Sumarno , Jalaluddin Jalaluddin , Hartama Dedy , Gunawan Indra
Published: February 2020

Mining age and technology have led to the emergence of an innovation that can help facilitate human activities, especially for parents in controlling and looking after babies. By implementing a sound monitoring system in the baby room based on the Arduino Atmega 328 microcontroller which functions to detect noise. Data from the voice sensor is processed by Arduino via a pin. So Arduino will give instructions to Buzzer to send alarm notifications