bluuebunny/crossref_metadata_2025 huggingface dataset:
Perancangan Aplikasi Silogisme Artikel Bahasa Batak Dengan Menerapkan Metode Textrank
Authors: Munthe Martha
Published: July 2024

Communicating with each other is one of the basic human traits. Communication serves as a means of interacting with one another. Humans sometimes want to master one foreign language. Especially if that language is popular. Humans also don't want to be outdated in mastering the language. dictionary then humans will be able to learn the language and know what language they want to master. So far, if someone wants to learn a foreign language, one example is Korean, the medium used to facilitate vocabulary mastery is through a dictionary. Because the dictionary form is still in the form of like books, inflexible, difficult to carry, resulting in less effective when out or on the road. A practical and effective new media such as smartphone media is needed because smartphones support various applications such as dictionary applications. The dictionary application on the smartphone does not search for words manually. But the search facility in the dictionary application makes it easier for users to get the words they want to look for. one of the string matching algorithms such as the text rank algorithm, it makes it easier and faster to search for words in the dictionary. It was explained that the Textrank Algorithm begins to match the pattern at the beginning of the text. Word matching starts from the left position until finally reaches the rightmost position, this algorithm will match the character of the pattern character with the characters in the corresponding text, until one of the following conditions is met, namely the character in the pattern and in the text being compared does not match (mismatch) and all the characters in the pattern match, then the algorithm will notify the discovery at this position.
Geographic Information System Pencarian Rumah Relokasi Dampak Erupsi Gunung Sinabung dengan Metode Formula Haversine
Authors: Aprianta Sinuraya Surya
Published: July 2024

The eruption of Mount Merapi Sinabung from 2010 to the present, resulted in a large number of residents who had to be evacuated because they could not contain a place, so it had to be relocated in order to neutralize the number of refugees. Where the relocation is carried out in various places both in rural areas and in buildings in the area around Karo district. However, with this relocation, many people, both relatives and families as well as a number of institutions wishing to provide extension assistance, find it difficult because of the lack of information about the location and distance that must be traveled in order to get to the relocation site. Based on these problems, the author will discuss the creation of a Geographic information system for finding relocation sites by applying the Haversine formula method. In order to be able to determine the distance to the relocation site so that later it can help the community in finding a relocation place
Educational Intervention Effect on Nurses’ Knowledge of Glasgow Coma Scale for Neurological Patient Assessment in Tertiary Hospitals in Edo State, Nigeria
Authors: Ehwarieme Timothy , Esewe Roselynd , Emina Anwuli
Published: July 2024

Context: Nigeria reports increasing cases of neurological patients requiring close monitoring using the Glasgow Coma Scale (GCS). Although nurses are key health personnel managing these patients, evidence suggests they lack knowledge of the GCS and neurological assessment.
Aim: This study assessed the effect of an educational intervention on nurses' knowledge of GCS for neurological patients’ assessment in selected tertiary hospitals in Edo State, Nigeria.
Methods: This is a quasi-experimental, non-equivalent control group, pre-post-test research design. The sample consisted of 98 nurses purposely selected from the neurological wards of the selected hospitals. A researcher-developed self-report questionnaire with a reliability Cronbach's alpha index of 0.832. Data analysis used descriptive and inferential statistics at the 5% significance level.
Results: Knowledge of GCS increased from a  (0%) pre-test to 29(60.4%) very good knowledge level post-test one and 15(31.3%) post-test two, whereas the control group had 0% throughout the three periods. Significant differences (p 0.000) over the assessment times were found in the intervention group. The post hoc test revealed statistically significant differences between pre-test versus post-test one/and post-test two. A chi-square analysis of association showed no association between socio-demographic characteristics and level of knowledge on GCS among participants pre and post-intervention for both study groups (p>0.05).
Conclusion: This study has convincingly demonstrated the effectiveness of the developed educational intervention package in improving nurses' knowledge of the GCS. The self-instructional format offers an appealing approach to promoting self-directed learning among nurses. This approach can empower nurses to confidently assess patients using the GCS, interpret scores accurately, and apply their knowledge in clinical practice.
School Heads’ Leadership Styles: Impact on Organizational Innovativeness and Performance of Public Elementary Schools in the New Normal
Authors: Diano Jr. Felix M. , Calbi Jamera S.
Published: July 2024

This study determines the impact of school heads’ leadership styles on organizational innovativeness and performance of public elementary schools in Cebu City Division in the new normal. Partial Least Squares Structural Equation Modeling (PLS-SEM) was utilized to investigate the linear causal relationships among the variables. Moreover, the study found that transformational leadership of the school head is not related to the organizational innovativeness of the school. However, transactional, and instrumental leadership influence the organizational innovativeness of the schools. On one hand, participative leadership only promotes product innovation, while supportive leadership augments management innovation directly. Lastly, product innovation of the school impacts the school’s performance.
Writing Errors of English as Second Language (ESL) Learners in the 21st Philippine Context
Authors: Munder Dania
Published: July 2024

To learn a second language (L2), once mastered, entails various prospects for Filipinos. One of the goals of the K-12 curriculum is to strengthen communicative competencies, which include linguistic competence; however, it was reported that the English Proficiency Index (EPI) of the Philippines has continuously declined in 2019, a year after the first batch of Senior High School graduated. As the country’s EPI declines, it may negatively impact the competitiveness of Filipinos in the international arena. Additionally, this result demonstrates the presence of errors in the writing performance of the learners despite the change in the curriculum. This research utilized a descriptive method to analyze the corpus from 100 ESL learners of a private school in Marawi City, Lanao del Sur. The findings illustrate that the majority, or 96.3221% were local errors and among these were mechanical or orthographic errors which ranked first with 1677 or 33.70%. Furthermore, the most committed error was misuse or omission of verb tenses, followed by capitalization and punctuation marks. With these results, it is important to expose learners to the target language (TL) and teachers to create remedial writing programs focusing on the weakest linguistic areas.
Assessing Stress Levels and Coping Strategies in the New Normal among Students of Magsaysay College
Authors: Padilla Arlyn A. , Cahilog Don T. , Sarong Jelyn S. , Arcilla Jr. Felix E.
Published: July 2024

The primary objective of this study was to assess stress levels and analyze coping strategies among Magsaysay College students. Utilizing a descriptive correlational research design, the study explored the relationship between students' demographic profiles, including age, gender, marital status, year level, family income, and reported stress levels. It also examined the correlation between stress levels and the use of coping strategies. The research concluded that demographic factors do not have a significant impact on stress levels among students and that stress is a ubiquitous challenge for students across different backgrounds. Interestingly, there is a slight negative correlation between family income and stress levels among students; this relationship is not statistically significant. This suggests that students show resilience and do not let the challenges of lower family income escalate their stress levels appreciably. A positive correlation was identified between stress levels and the employment of coping strategies, indicating that students tend to rely more on coping mechanisms as stress levels increase. It was recommended that Magsaysay College’s Guidance Center enhance its mental health support services by providing more resources, educational programs, and online counseling on effective coping strategies. Local Government Unit (LGU) of Magsaysay and other stakeholders are advised to collaborate on community-based support programs and invest in mental health initiatives to bolster the well-being of the students. Such collaborative efforts could significantly contribute to a more supportive learning environment, fostering students' academic success and personal growth.
Promoting Intellectual Property Propaganda Activities in Vocational Education Institutions: An Assessment from a Management Perspective
Authors: DangNguyen AnLong
Published: July 2024

Along with the comprehensive innovation of Vietnam’s education system, vocational education is positively changing, making great contributions to the country’s education system. Along with the university education system, vocational education is considered a place to create new knowledge and technology; but up to now, the number of applications to establish protection of industrial property rights, especially inventions, still accounts for a low rate; the understanding of education and training staff in vocational education institutions (VEIs) about intellectual property rights is not high. Based on the study of state legal documents on intellectual property rights, this article surveyed 300 people who are managers, teachers, students, and pupils at several educational institutions in Ho Chi Minh City through surveys and interview questions. VEIs do not pay much attention to intellectual property activities in general and intellectual property propaganda activities in particular; there is no long-term plan and policy for implementing intellectual property activities and intellectual property propaganda at VEIs. Based on that reality, and an assessment of the current situation combined with state legal documents, this article proposes some management solutions to promote intellectual property activities and intellectual property propaganda activities in VEIs in near the future.
Social Masks and Identity Construction in Lualhati Bautista’s Bata... Pa'no Ka Ginawa?
Authors: Costes Marie Rose L.
Published: July 2024

This research employs a descriptive qualitative method, combining textual analysis with cultural and socio-cultural perspectives, to investigate the portrayal of social masks, identity construction, and resilience in Lualhati Bautista's novels, focusing on "Bata, Bata... Pa'no Ka Ginawa?" The study explores how selected characters navigate social roles, adopt personas, and engage in impression management within Filipino society.  Through close reading and theoretical interpretation using Goffman's and Mead's frameworks, the research uncovers insights into the intricate dynamics of identity construction, social interaction, and resilience depicted in Bautista's narratives.  Significant findings include resilience among characters and its intersection with identity construction and social interaction. Additionally, the study reveals the influence of cultural norms, historical events, and socio-economic factors on characters' identity construction and resilience strategies.  It also highlights moments of authenticity, vulnerability, and resistance, analyzing how they challenge or reinforce social masks and identity performances.  Overall, the research contributes to understanding the complexities of Filipino identity and resilience in contemporary society as portrayed in literature.
Analysis of the Influence of Organizational Culture, Remuneration, and Job Satisfaction on the Performance of Education Personnel
Authors: Masri Rahmad Isa , Purba Sukarman , Rosnelli Rosnelli
Published: July 2024

The aim of this research is to determine: a description of the organizational culture profile and remuneration system; organizational culture influences the performance of education personnel; the remuneration system affects the performance of education personnel; the influence of the work environment on the performance of education personnel; and the influence of organizational culture, remuneration, and work environment simultaneously on the performance of education personnel. The research approach uses an associative approach. The research was conducted at the Medan Aviation Polytechnic. The research results show: (1) there are anomalies in the application of remuneration at the Medan Aviation Polytechnic; (2) individual organizational culture shows an unstandardized coefficient beta value of 0.531 and shows a significant value of <0.05, then H1 is accepted. Thus, organizational culture influences performance; (3) remuneration testing shows an unstandardized coefficient beta value of 0.248 and a significant value of <0.05, so H2 is accepted. Thus, remuneration influences performance; (4) if the unstandardized coefficient beta value is 0.135 and shows significance at <0.05, then H3 is accepted. Thus, job satisfaction influences performance; (5) the individual influence of organizational culture on performance with job satisfaction as an intervening variable shows unstandardized beta coefficients of 0.000 and shows significance at <0.05, as well as the influence of remuneration with job satisfaction as an intervening variable shows a significance <0.05. Thus, it can be concluded that organizational culture and remuneration variables influence performance by intervening with job satisfaction.
Translation Method in Translating Agatha Christie's Indonesian Version novel 'Kucing di Tengah Burung Dara
Authors: Kaur Harmit , Husein Rahmad , Pulungan Anni Holila
Published: July 2024

This study deals with eight translation methods applied in translating in Agatha Christie’s Indonesian Version Novel ‘Kucing di Tengah Burung Dara’. This study attempts to describe the eight methods namely: Word for Word Translation, Literal Translation, Faithful Translation, Semantic Translation, Adaptation Translation, Idiomatic Translation and Communicative Translation. The research methodology is qualitative. The dominant method in translating the novel is Communicative Translation so it gives the readers the same impact as the original does.
The Effect of Combination of Cone Drill (Zigzag) with Core Stability, Combination of Ladder Drill (Snake Jump) with Core Stability, and Speed on Agility of Futsal Players: A Factorial Experimental Design
Authors: Ilham Ilham , Alsyifa Putra Raffiandy , Agus Apri , Bafirman Bafirman , Arsil Arsil , Bahtra Ridho , Kurniawan Randi , Ndayisenga Japhet , Sibomana Alexandre
Published: July 2024

The game of futsal, known for its high intensity and dynamic nature demanding skill and robust physical fitness, particularly in agility, presents a significant challenge. Incorporating variations of cone and ladder drills in agility training, with a focus on enhancing balance through core stability training in conjunction with speed modulation as a key factor, is believed to impact players' agility players. Despite recognizing the individual significance of these training modalities in boosting agility performance, there remains a gap in fully comprehending their combined effects during futsal engagements. This research seeks to scrutinize the group differentials in agility training, factoring in speed variations in relation to futsal players' agility levels. The study defined agility training cohorts as a combo group of cone drill with core stability and a combination group of ladder drill alongside core stability, while speed was categorized as high or low. Employing an experimental methodology with a 2 x 2 factorial design, the study enlisted 20 players aged 17.1 ± 0.76 years through random selection. Agility training, conducted thrice weekly over a six-week period, emphasized swift and dynamic movements alongside maintaining balance. Speed and agility metrics were assessed using the 30m acceleration test and Illinois agility test, then subjected to statistical scrutiny via a two-way ANOVA at a significance level of 0.05. Results revealed that both training methodologies benefited participants with elevated speed (P<0.05). Notably, agility training incorporating ladder drill exercises and core stability training exhibited superior outcomes for high-speed performers (P<0.05). Conversely, individuals with lower speed levels potentially benefitted more from a combination of ladder drill and core stability (P<0.05). These findings furnish crucial insights for futsal coaches and trainers looking to craft tailored training regimens aimed at enhancing agility performance effectively.
Keywords: Cone Drill, Ladder Drill, Core Stability, Speed, Agility, Futsal
ARTICLE RETRACTED DUE TO PLAGIARISM BY THE AUTHORMethods of physical rehabilitation of schoolchildren aged 15-17 with cervical osteochondrosis
Authors: Polevoy Georgiy
Published: July 2024

Background. The problem of rehabilitation of children with cervical osteochondrosis can be solved by creating a special technique and performing additional exercises at home. The objective of the study is rehabilitation of high school students with osteochondrosis of the cervical spine. Methods: boys and girls aged 15-17 who were diagnosed with osteochondrosis of the cervical spine took part in the research. A total of 38 schoolchildren took part in the study. The study was conducted from February 28 to May 26, 2023 on the basis of several secondary schools in the city of Kirov. All students in both groups studied according to the standard program 3 times a week. Children from experimental group B additionally performed sets of physical exercises from the experimental methodology. The study used tests that evaluate the static strength of the abdominal and back muscles, the flexibility and endurance of the cervical spine and the speed and strength abilities of the arm muscles. When analyzing the results, their statistical processing was carried out using the arithmetic mean, square deviation, error and difference. Confidence at p<0.05. Results: According to the results of the research, it was found that children from the control group were able to slightly improve the studied indicators to 10.6%, the increase in indicators from the beginning to the end of the study on all tests turned out to be unreliable (p>0.05). In the experimental group, at the end of the study, the indicators for all tests improved from 23.5% to 66.7% (p<0.05). Thus, the experimental technique is more effective in the treatment of cervical osteochondrosis than the generally accepted technique.Conclusions: Systematic physical education with the use of special physical exercises aimed at eliminating problems in the cervical spine give a significant effect in the rehabilitation of cervical osteochondrosis. The indicators of the static strength of the abdominal and back muscles will improve, the flexibility and endurance of the cervical spine will also increase, and the speed and strength capabilities of the arm muscles will increase.
Keywords: School children's health, Lifestyle, Rehabilitation, Joint mobility, Physical therapy.
Study on the Impact of Multi-brand Strategy on Perceived Value and Consumption Intention: A Case of the Chain Restaurant Industry
Authors: Liao Ying-hao
Published: July 2024

Abstract

The restaurant service industry is highly competitive, and in recent years, multi-brand strategies have gained increasing importance. By differentiating various brands, businesses can cater to diverse consumer needs and preferences, thereby enhancing their market share.
This study explores the impact of multi-brand strategies on the restaurant service industry, focusing on whether perceived value influences consumer purchase intentions within a multi-brand context. The findings aim to help businesses understand the advantages of developing multi-brand strategies and provide actionable recommendations.
Using a survey methodology, this study collected and analyzed 238 valid samples. The results indicate that the development of multi-brand strategies positively impacts both the perceived value and the purchase intentions of consumers in the restaurant service industry, enhancing their perception and willingness to engage with the services offered.

Keywords: Multi-brand, Perceived Value, Consumption Intention.
Evaluation of Antarctic strains of Bacillus sp. as plant growth promoting bacteria
Authors: Zambrano-Solórzano Ángela , Guzmán-Cedeño Ángel , Pincay María , Chicaiza Jonathan , Zambrano Diego
Published: July 2024

In agriculture, efficient microorganisms are used, among them plant growth-promoting bacteria. This work aimed to determine, in vitro, the mechanism of action in strains of Bacillus sp. isolated from Antarctica. The analyzed characteristics of the bacterium were: catalase and hemolysis tests, Gram stain, phosphate solubilization, growth without a nitrogen source, siderophore production, and survival at different values of pH, NaCl, and temperature, which confirmed the ecological plasticity and adaptation of these strains in environments other than their origin. According to the desirable characteristics, the T5, GB-70, and B-6 strains were chosen and added to two substrates: clay and clay-compost mixture, which were sterilized and placed in 200 mL glass bottles, and a corn seed was planted in each of them. After two weeks, the following parameters were evaluated: length of root (LR), seedling height (AP), and shoot diameter (DT). The simple effect of the strains as independent variables and their interaction did not significantly affect the response variables evaluated, recording the following averages: 12.84 cm (LR), 15.28 cm (AP), and 2.26 cm (DT). Considering the substrate, the compost + clay significantly (p<0.05) influenced the LR and DT characteristics of the seedlings, with averages of 14.44 and 2.38 cm, respectively. The observed mechanisms of action distinguish promising strains that could be validated at the field level in agricultural production systems when inoculated in organic fertilizers.
Keywords: antarctic microorganisms, beneficial bacteria, plant growth.
Splenic infarction may be the first sign of granulomatosis with polyangiitis: case reports
Authors: Üsküdar Cansu D. , Yildirim R. , Korkmaz C.
Published: July 2024

Granulamatous polyangiitis (GPA) is a rare systemic vasculitis that makes up most of the antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitis (AAV). The disease is more likely to affect the upper and lower respiratory tract, kidney and skin. The gastrointestinal tract involvement is more rare. In the general population, spleen infarction is a rare condition. Most spleen infarcts are asymptomatic, and most patients receive a diagnosis by chance during the evaluation. The most common causes of non-traumatic spleen infarction in the general population include cardiac causes such as atrial fibrillation, infections, thrombophilic conditions, and malignancies. In rheumatic diseases, various spleen involvement has been identified, such as splenomegaly, spleen rupture, spleen abscess, asplenia and spleen infarction. The development of spleen infarct in antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) is well known. It is not well known whether GPA is a risk factor for spleen infarction. However, publications including cases of developing spleen infarction due to GPA are increasing. This review highlights the occurrence of spleen infarction in patients with GPA, by presenting two GPA cases with splenic infarction. It also emphasizes that spleen infarction can occur in GPA and may frequently be without symptoms.
Incidence of mental disorders in Kazakhstan in 2011-2020: an information-analytical study
Authors: Bekaryssova D. , Mutalipova G. , Shaimerdenova G.
Published: July 2024

Introduction. Mental disorders, characterized by disturbances in thinking, feeling, and behavior, pose a significant medical and social challenge. They affect a substantial portion of the population, leading to profound health implications and diminished quality of life. Despite the considerable interest in this area, data regarding the prevalence of mental disorders in the Republic of Kazakhstan still need to be made available. This study aims to analyze the trend of mental disorder prevalence in Kazakhstan from 2011 to 2020, considering various factors such as gender, age, and residency.
Methods. This study employed an informational and analytical approach. Data from 10 statistical compilations of the Ministry of Health of the Republic of Kazakhstan spanning from 2011 to 2020 were utilized to assess the prevalence of mental disorders. Information about morbidity falling under the category of "mental disorders and behavioral disorders" was incorporated. The data were processed and presented in terms of absolute values and relative indicators.
Results and conclusions. Analyzing mental disorder incidence data in Kazakhstan over the ten years revealed several trends. Overall morbidity rates showed a declining trend, notwithstanding some years witnessing minor increases in morbidity. The relative incidence rates also decreased, as evidenced by data per 100,000 population. Primary morbidity demonstrated a general decline, with a notable decrease observed in the first half of the study period. Across age groups, morbidity rates decreased in all categories, with the highest rates observed among adults. Moreover, there was a reduction in morbidity rates in both urban and rural populations, albeit with urban areas consistently exhibiting higher rates than rural areas. These findings could inform the development of interventions aimed at enhancing the mental well-being of the population and improving the management of this medical and social challenge in the future.
Analysing Mahabharata through the Lens of Theory of Just War
Authors: B K Bhuvesha
Published: July 2024

Of the world filled with the recorded history of western wars, Mahabharata is one of the prominent just war fought in the Indian history. It satisfies the principles of the theory of just war, namely, jus ad bellum and jus in bello. Jus ad bellum applies to the episodes of Mahabharata prior to the 18 days’ war- Kurukshetra. Notably, Kurukshetra known as the “dharma yuddha-the battle for just,” satisfies the principles of jus in bellus. However, the modern relevance of the theory is analysed with the case of Kosovo war. The intentions behind NATO’s intervention resembles the principles of jus ad bellum. While the element of jus in bello is witnessed amidst the Operation Allied Force. Apparently, this paper examines the above cases through the factor of just and not based on the stands of parties involved. It attempts to compare and assess the convergences Kurukshetra of Mahabharata and Kosovo war through the lens of principles of theory of just war.
DINAMIK BOSHQARISH OBYEKTLAR HOLATINI BAHOLASH MASALALARINING DASTURIY TA’MINOTI
Authors: Zaripova Shahlo
Published: July 2024

Maqolada dinamik boshqarish obyektlar holatini baholash masalalarining dasturiy ta’minoti keltirilgan. Dinamik jarayonni boshqarishning adaptiv tizimini funksional sxemasi taklif etilgan. Dinamik boshqarish obyektlarini avtomatlashtirish, boshqarish yoki modellashtirish masalasi ko‘rilayotganda avvalo jarayonni boshqaruv obyekti sifatida ko‘rish chiqish lozim. Keltirilgan algoritmlar orqali ishlab chiqarishlarining dinamik obyektlarini avtomatlashtirish va boshqarish masalalarida qo‘llash imkonini beradi.
Alkaline Phosphatase: The Poor Man's iPTH - An Affordable Approach to Bone Health Assessment
Authors: Sourabh Sharma  , Himanshu Verma  , Sanjay Kalra
Published: July 2024

This review delves into relatively less discussed role ofalkaline phosphatase (ALP) as an accessible alternative tointact parathyroid hormone (iPTH) in the context of bonehealth assessment, particularly focussing on its potentialboon for underprivileged individuals with chronic kidneydisease (CKD) in South Asia. The financial constraints facedby this demographic often hinder regular monitoring ofiPTH levels. ALP emerges as a promising surrogate, offeringa cost-effective and practical solution for bone healthevaluation in resource-constrained settings.Keywords: PTH, Intact Parathormone, AlkalinePhosphatase, ALP, Chronic Kidney Disease, Bone Health
Stereotactic radiosurgery and radiotherapy in complex treatment of patients with intracranial pilocytic astrocytomas
Authors: Trunin Yury Yu. , Golanov Andrey V. , Konovalov Alexander N. , Pronin Igor N. , Likhterman Leonid B. , Zagirov Ruslan I.
Published: July 2024

The paper reports the analysis of the stereotactic irradiation outcomes in 430 patients with pilocytic astrocytomas (PAs), who underwent treatment in 2005–2018. The comprehensive approach to treatment of patients with intracranial pilocytic astrocytomas (PAs) that includes surgical removal, drug therapy (mostly in young children) and radiation therapy, is justified. The paper defines the roles of stereotactic radiosurgery and radiotherapy as the methods of choice used in the radiation therapy of patients with pilocytic astrocytomas. These methods show high conformity and selectivity, which is of special importance in patients with the PA localization in the functionally important structures.
Efficacy of using psychopharmacotherapy and psychotherapy for treatment and prevention of mental disorders in patients with neurological diseases
Authors: Medvedev Vladimir E. , Kotova Olga V. , Zuikova Nadezhda L. , Salyncev Igor V. , Palin Aleksandr V. , Miheeva Olga V.
Published: July 2024

Psychopharmacotherapy and psychotherapy methods are used for psychopathological conditions in neurological patients. The experience of psychopharmacotherapy combined or not combined with psychotherapy in 242 patients with neurological disorders is reported. Beneficial effects of psychopharmacotherapy are observed in 70.1% of cases, while that of psychopharmacotherapy combined with psychotherapy are reported in 78.0% of cases. The data on efficacy and tolerability of a number of psychotropic agents are provided. It has been shown that the use of psychotropic agents and psychotherapy results in the reduced rate of exacerbation of neurological disorders, reduces the rate of visits to neurologist. Optimization of psychopharmacotherapy and psychotherapy in patients with nervous system disorders is discussed.
Manifestation of cardiovascular pathology on oral mucosa and red lip border
Authors: Lutskay Irina K. ,   Belarusian Medical Academy of Postgraduate Education, Kamyshnikov Vladimir S. ,   Belarusian Medical Academy of Postgraduate Education
Published: July 2024

Pathological changes in oral tissues often accompany general diseases of the body, including cardiovascular failure. Knowledge by a general practitioner, therapist, cardiologist of manifest manifestations from the mucous membrane in coronary heart disease makes it possible to ensure timely referral of patients to a dentist for medical and preventive measures. The latter serve to prevent complications that aggravate the severity.
Rossolimo–Melkersson–Rosenthal syndrome in 14 years old child with Down`s syndrome. Case report
Authors: Glebova Larisa I. ,   Yevdokimov Moscow State University of Medicine and Dentistry, Zadionchenko Ekaterina V. ,   Yevdokimov Moscow State University of Medicine and Dentistry
Published: July 2024

Rossolimo–Melkerson–Rosenthal syndrome is not so often diagnosed in childhood. It is noted that children's syndrome occurs as a monosymptom in the form of macrocheilitis. The clinic of the syndrome can be aggravated by other somatic abnormalities, for example, the presence of Down's disease in a child. In this disease, a prominent place is occupied by changes in the mucous membrane of the oral cavity, tongue, lips. Recurrent cracks appear on the lips, most sharply manifested by the period of puberty. Treatment of patients with Rossolimo–Melkerson–Rosenthal syndrome in combination with Down's disease is usually carried out by doctors of various specialties (dermatologists, dentists, neurologists).
Antihistamines in the treatment of allergic diseases: not as simple as it seems!
Authors: Guschin Igor S. ,   National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia, Kurbacheva Oksana M. , Osipova P.S. ,   National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia,   Yevdokimov Moscow State University of Medicine and Dentistry,   National Research Center – Institute of Immunology Federal Medical-Biological Agency of Russia
Published: July 2024

According to WHO, up to 35% of the world's population suffers from allergic diseases, and this number is growing exponentially. Histamine has been proven to play a key physiological role in the pathogenesis of allergic disorders by affecting tissues through the activation of H1-receptors. H1-antagonists (antihistamines) are widely used to treat allergic disorders, being one of the most prescribed classes of drugs. The development of medications with high specific activity and low incidence of unwanted side effects is the main goal of pharmaceutical research, so antihistamines have evolved significantly since their first generation was introduced more than 50 years ago. This review analyzes aspects of classification and concepts of clinical use of antihistamines considering their individual specificity.
Allergy immunotherapy in combination with biological therapy in moderate and severe asthma
Authors: Kulichenko Dariya S. ,   National Research Center Institute of Immunology, Federal Medical and Biological Agency of Russia, Pavlova Ksenia S. , Kurbacheva Oksana M. , Ilina Natalia I. ,   National Research Center Institute of Immunology, Federal Medical and Biological Agency of Russia,   National Research Center Institute of Immunology, Federal Medical and Biological Agency of Russia,   Yevdokimov Moscow State University of Medicine and Dentistry,   National Research Center Institute of Immunology, Federal Medical and Biological Agency of Russia,   Yevdokimov Moscow State University of Medicine and Dentistry,   Pirogov Russian National Research Medical University
Published: July 2024

Background. Allergen immunotherapy (AIT) is a pathogenetic substantiated method for the allergic disease’s treatment, which allows reducing the symptom severity and decreasing the medication use. Uncontrolled severe asthma is a contraindication for AIT. The appointment of biological therapy helps to improve the asthma control, but their cancellation is impossible. The combined use of the biological therapy and AIT makes it possible to achieve the long-term symptoms control in patients with severe asthma, increase the AIT safety, and probably stop biological therapy. Aim. To evaluate the efficacy and safety of combination therapy with dupilumab and AIT in patients with severe asthma. Materials and methods. The study involved 30 adult patients with moderate to atopic severe asthma. Patients was randomized for 3 groups: group 1: standard therapy (0–52 weeks) + dupilumab (0–16 weeks) + AIT (12–16 weeks); group 2: standard therapy without biological therapy (0–52 weeks) + AIT (12–16 weeks); group 3: standard therapy without biological therapy, without AIT (0–52 weeks). We evaluated the asthma control and comorbidities using questionnaires (ACQ, AQLQ, TNSS, SNOT-22, DQLQ), respiratory function (FEV1), the number of exacerbations and adverse events At control points (initially, after 12, 20 and 52 weeks). Results. As a result of the appointment of dupilumab it was possible to quickly achieve asthma control and comorbidities (12 wk), which made it possible to successfully conduct AIT. In the first group, symptom control is maintained even after discontinuation of both dupilumab and AIT. ACQ-6 52 wk: 1 group – 0.30±0.21; 2 group – 1.62±0.51; 3 group – 2.76±0.85. FEV1 52 wk: group 1 – 81.47±7.48%; group 2 – 73.99±6.17%; group 3 – 65.02±7.23% for 3 group (р<0.01). In the first group, there weren’t adverse events that allowed complete AIT successfully, unlike for the second group, where, maximum tolerated allergen dose was lower due to development of systemic reactions. Conclusion. Combined treatment with dupilumab and AIT allows to quickly achieve a control, decrease a background therapy and adverse events during the AIT. The control of asthma symptoms and the effect of AIT were maintained even after the end of dupilumab therapy.
According to the World Health Organization, acute respiratory viral infections (ARVIs) account for 70–85% of all cases of infectious diseases in the world. High prevalence rates of ARVIs, influenza and COVID-19 require the search for new methods to prevent, treat, and control epidemics. Furthermore, there are significant economic losses due to high incidence and temporary disability rates. ARVIs constitute a heterogenous group of the infectious respiratory tract disorders caused by numerous viruses, such as influenza virus, parainfluenza virus, respiratory syncytial virus, adenovirus, coronavirus, and many other viruses. Symptoms of various ARVIs have much in common and include fever, cough, chest pain, headache, myalgia, asthenia, anosmia, etc. The paper discusses the features of diagnostic search and treatment tactics in seasonal ARVIs, as well as feasibility of preventive measures. The data of meta-analyses and systematic reviews are used to explore the role and potential of zinc, selenium, vitamin C, vitamin A, and vitamin E for prevention and treatment of bronchopulmonary diseases in adults.
Authors: Popova Elena N. ,   Sechenov First Moscow State Medical University, Ponomareva Liubov A. , Chinova Alina A. , Andrianov Aleksandr I. ,   Sechenov First Moscow State Medical University,   Pirogov Russian National Research Medical University,   People’s Friendship University of Russia (RUDN University)
Published: July 2024

According to the World Health Organization, acute respiratory viral infections (ARVIs) account for 70–85% of all cases of infectious diseases in the world. High prevalence rates of ARVIs, influenza and COVID-19 require the search for new methods to prevent, treat, and control epidemics. Furthermore, there are significant economic losses due to high incidence and temporary disability rates. ARVIs constitute a heterogenous group of the infectious respiratory tract disorders caused by numerous viruses, such as influenza virus, parainfluenza virus, respiratory syncytial virus, adenovirus, coronavirus, and many other viruses. Symptoms of various ARVIs have much in common and include fever, cough, chest pain, headache, myalgia, asthenia, anosmia, etc. The paper discusses the features of diagnostic search and treatment tactics in seasonal ARVIs, as well as feasibility of preventive measures. The data of meta-analyses and systematic reviews are used to explore the role and potential of zinc, selenium, vitamin C, vitamin A, and vitamin E for prevention and treatment of bronchopulmonary diseases in adults.
Relationship of galectin-3 and brain natriouretic peptide levels with the type of left ventricle remodeling in patients with coronary heart disease after coronary arto bypass graft
Authors: Styazhkina Yulia A. ,   Ural State Medical University, Grishina Irina F. , Peretolchina Tatyana F. , Poletaeva Nina B. , Nikolaenko Olga V. ,   Ural State Medical University,   Ural State Medical University,   Ural State Medical University,   Ural State Medical University
Published: July 2024

Relevance. Today, the search for biomarkers capable of predicting the duration of rehabilitation after CABG in patients with CAD is relevant. Aim. To assess the features of the left cardiac chamber remodeling with regard to the levels of NT-proBNP and galectin-3 in patients with CAD after CABG. Methods. The study involved 100 males with CAD, who underwent CABG. Group 1 included 58 patients, who started working within 4 months after intervention. Group 2 included 42 patients, whose rehabilitation period exceeded 4 months. Echocardiography was performed in all patients, the levels of galectin-3, NT-proBNP were determined 1 and 4 months after CABG. Results. Assessment of the LV remodeling variants 1 month after CABG showed that hypertrophic variants of remodeling prevailed in group 2, while in group 1 these were reported less than in half of the cases. The increase in the rate of unfavorable LV remodeling variants by month 4 was observed in group 2. Initial comparison showed that the galectin-3 and NT-proBNP levels in group 2 were significantly higher than that in group 1 (17.95 (17.2÷19.3) vs. 11.35 (8.2÷14.7) ng/mL, p<0.01 and 372 (320.3÷445) vs. 287.5 (232.5÷391.3) pg/mL, p<0.01, respectively). These indicators showed no upward trend by month 4 in group 1, while in group 2 a significant increase in the levels of galectin-3 and NT-proBNP was reported. Positive correlations of varying strength between the galectin-l levels and the LV remodeling types, NT-proBNP levels and the LV remodeling types were revealed in both groups. Discussion. The association of high marker (galectin-3 and NT-proBNP) levels with unfavorable LV remodeling types in the group with prolonged recovery was demonstrated during the study. The studied markers are proxy indicators for the processes underlying maladaptive morphofunctional remodeling of myocardium resulting in myocardial dysfunction, which can be the cause of prolonged recovery after the CABG surgery. Conclusions. The correlations revealed can have clinical significance for early detection of LV remodeling in patients with CAD associated with prolonged recovery after CABG.
Role of glycemic control in patients with type 2 diabetes mellitus
Authors: Ovsyannikov Konstantin V. ,   Biomedical University of Innovation and Continuing Education – branch of Burnazyan Federal Medical Biophysical Center FMBA, Praskurnichiy Evgeny A. ,   Clinical Hospital No85 FMBA,   Biomedical University of Innovation and Continuing Education – branch of Burnazyan Federal Medical Biophysical Center FMBA
Published: July 2024

It is well-known that patients with type 1 and 2 diabetes mellitus are at high risk of complications of micro- and macrovascular disease. Furthermore, the relationship between elevated blood glucose levels and microvascular complications is likely to be direct and is generally specific for diabetes. However, the correlation with macrovascular risk is more complex, multifactorial and not limited to hyperglycemia only. The paper considers the relationship between the macro- and microvascular damage to the target organs associated with DM and cardiovascular risk. The review of studies focused on assessing the effectiveness of blood glucose level reduction in type 2 diabetes mellitus in the context of cardiovascular safety is provided. Advanced DM treatment methods are discussed. Special attention is paid to self-monitoring of blood glucose as one of the most important factors of the DM management and prevention of complications.
Pengaruh Literasi Keuangan Syariah, Penggunaan Shopee Paylater dan Lifestyle Terhadap Perilaku Konsumtif: Studi Kasus pada Mahasiswa Program Studi Perbankan Syariah UMSU
Authors: Putri Ayu Lestari  , Khairunnisa
Published: July 2024

This research was conducted with the aim of finding out the influence of sharia financial literacy, use of shopee paylater, lifestyle on the consumptive behavior of students in the UMSU Sharia Banking Study Program. The type of approach used is quantitative with an associative type of research. The research population was 190 UMSU Sharia Banking Study Program students, while the sample used was 130 respondents who were the research sample. This research uses Purposive Sampling technique. The data used is primary data and the data collection technique uses a questionnaire via Google Form. The variables used are the independent variables in the form of financial literacy, use of Shopee Paylater and also Lifestyle, while the dependent variable is consumer behavior. The data analysis technique used in this research uses Multiple Linear Regression Test, Hypothesis Test (t Test and F Test), and Coefficient of Determination. Data processing in this research used SPSS (Statistical Package For The Social Sciences) version 29.00 (2024). Based on the research results, it shows that Sharia Financial Literacy has a positive but not significant influence on student consumptive behavior. Using Shopee Paylater has a positive and significant influence on student consumptive behavior. And Lifestyle has a positive and significant effect on student consumption behavior.
Dampak Hilirisasi Terhadap Pendapatan Petani Kelapa Sawit di Nagari Talang Binjai Kecamatan Silaut Kabupaten Pesisir Selatan
Authors: Anggelin Rahmadani  , Saputra Megi , Firdaus Nil , Pasrizal Himyar , Elvina Annisa
Published: July 2024

This research aims to analyze the impact of downstreaming on the income of oil palm farmers in Nagari Talang Binjai, Silaut District, Pesisir Selatan Regency. The main problem in this research is the extent to which palm oil downstreaming helps increase the income of oil palm farmers in Nagari Talang Binjai, Silaut District, Pesisir Selatan Regency. This type of research is field research with a qualitative approach. The data analysis technique used is Miles and Huberman which includes reduction, presentation and drawing conclusions. The results of this research found that the downstreaming of palm oil stabilized the selling price of palm oil to farmers. Which can help stabilize the income of oil palm farmers in Nagari Talang Binjai, Silaut District, Pesisir Selatan Regency. Moreover, the European Union is boycotting palm oil commodities and their derivatives produced in Indonesia. After discussion, the Indonesian government must continue to carry out research regarding downstream palm oil and increase its costs. This is so that scientists can immediately produce one hundred percent vegetable energy, whether in the form of diesel or fuel, even in other forms of vegetable energy. After that, mass production of every vegetable energy product from palm oil will be carried out as soon as possible. Due to economic threats from abroad in the form of boycotts, reducing imports and planting oil palm, several countries have begun to implement them. By downstreaming palm oil, Indonesia will become a developed and strong country, and can bring prosperity to its people, especially oil palm farmers in Nagari Talang Binjai, Silaut District, Pesisir Selatan Regency.
Pengaruh Promosi, Citra Merek, Brand Ambassador, dan Kualitas Produk Terhadap Keputusan Pembelian Somethinc
Authors: Farah Rizqy Salsabila  , Alfalisyado  , Tri Septin Muji Rahayu  , Alfato Yusnar Kharismasyah
Published: July 2024

This  purpose of this study is understand how consumer characteristics and analyze the effect of promotion, brand image, brand ambassador, and product quality on purchasing decisions on Somethinc products. The method used in this study is quantitative method. The number of samples in this study were 114 respondents who were determined by purposive sampling technique with the criteria of active university students in Purwokerto City who had purchased Somethinc products. The data analyzed is primary data collected using a questionnaire and processed by multiple regression analysis methods using the SPSS program version 26. Instrument testing states that all indicators are valid and all variables are declared reliable. The t-test results show that the promotion and brand image variables partially have a positive and significant effect on purchasing decisions, while the brand ambassador and product quality variables do not affect purchasing decisions. The F test results show that the regression model in this study is suitable for hypothesis testing. The coefficient of determination (Adj. R2) test results show the ability of the independent variables to explain the dependent variable by 59.1%.