bluuebunny/crossref_metadata_2025 huggingface dataset:
Redefinition and Measurement Dimensions of Sustainable Employability Based on the swAge-Model
Authors: Deng Jianwei , Liu Jiahao , Deng Wenhao , Yang Tianan , Duan Zhezhe
Published: December 2021

Objectives: To solve the labour shortage, we clarify the definition and dimensions of sustainable employability, and make it possible to develop sustainable employability scales in the future and lay the foundation for subsequent quantitative research. Finally, people’s sustainable employability can be improved. Highly sustainable employability employees can continue to work in the labour market and their working lives can be prolonged. Labour market supply will increase and labour shortage will be partly solved. Methods: We discuss the concept of sustainable employability based on some previous studies. Our conclusion is that the existing definitions and measurement dimensions are problematic. The swAge-model, a tool that helps us understand how to make working life more sustainable and healthier for all ages, can be the basis of sustainable employability. Results: We develop a discussion paper concerning the definition and measurement dimensions of sustainable employability using the swAge-model with an added factor of intrinsic work value and the dynamic chain. Conclusions: Our definition of sustainable employability takes environmental factors into consideration and makes it clear that it is not a solely personal characteristic, but the result of an interaction between individuals and the environment, thus distinguishing employability from work ability. We use the swAge-model as a basis to make the composition of our definition more logical and informed. Our measurement dimensions are clearly described to facilitate the future development of a scale, and our concept may ultimately help to extend the working lives of older and retired workers and thus solve the future labour shortage problem.
FeCl3-Modified Carbonaceous Catalysts from Orange Peel for Solvent-Free Alpha-Pinene Oxidation
Authors: Kamińska Adrianna , Miądlicki Piotr , Kiełbasa Karolina , Serafin Jarosław , Sreńscek-Nazzal Joanna , Wróbel Rafał Jan , Wróblewska Agnieszka
Published: December 2021

The work presents the synthesis of FeCl3-modified carbonaceous catalysts obtained from waste orange peel and their application in the oxidation of alpha-pinene in solvent-free reaction conditions. The use of waste orange peel as presented here (not described in the literature) is an effective and cheap way of managing this valuable and renewable biomass. FeCl3-modified carbonaceous materials were obtained by a two-stage method: in the first stage, activated carbon was obtained, and in the second stage, it was modified by FeCl3 in the presence of H3PO4 (three different molar ratios of these two compounds were used in the studies). The obtained FeCl3-modified carbon materials were subjected to detailed instrumental studies using the methods FT-IR (Fourier-transform Infrared Spectroscopy), XRD (X-ray Diffraction), SEM (Scanning Electron Microscope), EDXRF (Energy Dispersive X-ray Fluorescence) and XPS (X-ray Photoelectron Spectroscopy), while the textural properties of these materials were also studied, such as the specific surface area and total pore volume. Catalytic tests with the three modified activated carbons showed that the catalyst obtained with the participation of 6 M of FeCl3 and 3 M aqueous solutions of H3PO4 was the most active in the oxidation of alpha-pinene. Further tests (influence of temperature, amount of catalyst, and reaction time) with this catalyst made it possible to determine the most favorable conditions for conducting oxidation on this type of catalyst, and allowed study of the kinetics of this process. The most favorable conditions for the process were: temperature of 100 °C, catalyst content of 0.5 wt% and reaction time 120 min (very mild process conditions). The conversion of the organic raw material obtained under these conditions was 40 mol%, and the selectivity of the transformation to alpha-pinene oxide reached the value of 35 mol%. In addition to the epoxy compound, other valuable products, such as verbenone and verbenol, were formed while carrying out the process.
Transverse Vibration of Viscoelastic Sandwich Structures: Finite Element Modeling and Experimental Study
Authors: Huang Zhicheng , Pan Jinbo , Yang Ziheng , Wang Xingguo , Chu Fulei
Published: December 2021

In the present work, the nonlinear vibration behavior of elastic-viscoelastic-elastic sandwich (EVES) beams is studied. A finite element (FE) equation taking intoaccount the transverse compression deformation of the viscoelastic core for the EVES beams is derived. In order toaccurately characterize the frequency-dependent feature of the viscoelastic materials layer, athird-order seven-parameter Biot model isused. A 2-node 8-DOF element is established to discretize the EVES beams. The experimental testing onEVES beams validates the numerical predication of the FE model. Numerical and analytical investigations are carried on a series of EVES beams with different thicknesses. The results indicate that the presented FE model has better accuracy in predicting the natural frequency of the sandwich beams, and in predicting damping, the accuracy is related to the thickness of each layer. The results of this paper have important reference values for the design and optimization of the viscoelastic sandwich structure.
Low-Cycle Fatigue of FRP Strips Glued to a Quasi-Brittle Material
Authors: Martinelli Enzo , Caggiano Antonio
Published: December 2021

This paper aims at further advancing the knowledge about the cyclic behavior of FRP strips glued to quasi-brittle materials, such as concrete. The results presented herein derive from a numerical model based on concepts of based on fracture mechanics and already presented and validated by the authors in previous works. Particularly, it assumes that fracture processes leading to debonding develop in pure mode II, as is widely accepted in the literature. Starting from this assumption (and having clear both its advantages acnd shortcomings), the results of a parametric analysis are presented with the aim of investigating the role of both the mechanical properties of the interface bond–slip law and a relevant geometric quantity such as the bond length. The obtained results show the influence of the interface bond–slip law and FRP bond length on the resulting cyclic response of the FRP-to-concrete joint, the latter characterized in terms of S-N curves generally adopted in the theory of fatigue. Far from deriving a fully defined correlation among those parameters, the results indicate general trends that can be helpful to drive further investigation, both experimental and numerical in nature.
Investigations of Model Multilayer Ceramic Casting Molds in a Raw State by Nondestructive Methods
Authors: Żaba Krzysztof , Puchlerska Sandra , Książek Marzanna , Sitek Ryszard , Wiśniewski Paweł , Mizera Jarosław
Published: December 2021

This article presents the results of research on the use of modern nondestructive methods such as 3D scanning, thermography and computed tomography (CT) to assess the quality of multilayer ceramic molds. Tests were performed on spherical samples of multilayer ceramic molds in the raw state. Samples were made of molding sands composed of quartz and molochite powders, the alcoholic binder hydrolyzed ethyl silicate (ZKE) and an aqueous binder based on colloidal silica. Thickness measurements of spherical forms were made using a 3D scanner. Porosity measurements were made using CT. Additionally, thermography observations of the mold cooling process were made with controlled temperature and humidity. The results of temperature measurements of samples were compared with measurements of thickness and porosity. The practical goal was to determine the possibility of using thermography, 3D scanning and CT as a quick method for detecting mold defects by varying their thickness, porosity and cracks and for final verification of the ceramic molds’ condition before casting.
Habituation of Somatosensory Evoked Potentials in Patients with Alzheimer’s Disease and Those with Vascular Dementia
Authors: Currà Antonio , Marinelli Lucio , Cotellessa Filippo , Mori Laura , Avanti Chiara , Greco Daniela , Gorini Manuela , Missori Paolo , Fattapposta Francesco , Trompetto Carlo
Published: December 2021

Background and Objectives: The most prevalent dementia are Alzheimer’s disease and vascular dementia. There is evidence that cortical synaptic function may differ in these two conditions. Habituation of cortical responses to repeated stimuli is a well-preserved phenomenon in a normal brain cortex, related to an underlying mechanism of synaptic efficacy regulation. Lack of habituation represents a marker of synaptic dysfunction. The purpose of this study was to assess the habituation of somatosensory evoked potentials (SEPs) in 29 patients affected by mild-to-moderate Alzheimer’s disease (AD-type) or vascular (VD-type) dementia. Materials and Methods: All patients underwent a clinical history interview, neuropsychological evaluation, and neuroimaging examination. SEPs were elicited by electrical stimulation of the right median nerve at the wrist. Six-hundred stimuli were delivered, and cortical responses divided in three blocks of 200. Habituation was calculated by measuring changes of N20 amplitude from block 1 to block 3. SEP variables recorded in patients were compared with those recorded in 15 age- and gender-matched healthy volunteers. Results: SEP recordings showed similar N20 amplitudes in AD-type and VD-type patients in block 1, that were higher than those recorded in controls. N20 amplitude decreased from block 1 to block 3 (habituation) in normal subjects and in VD-type patients, whereas in AD-type patients it remained unchanged (lack of habituation). Conclusions: The findings suggest that neurophysiologic mechanisms of synaptic efficacy that underneath habituation are impaired in patients with AD-type dementia but not in patients with VD-type dementia. SEPs habituation may contribute to early distinction of Alzheimer’s disease vs. vascular dementia.
A Low-Band Multi-Gain LNA Design for Diversity Receive Module with 1.2 dB NF
Authors: Rikan Behnam S. , Kim David , Choi Kyung-Duk , Asl Seyed Ali H. , Yoo Joon-Mo , Pu YoungGun , Kim Seokkee , Huh Hyungki , Jung Yeonjae , Lee Kang-Yoon
Published: December 2021

This paper presents and discusses a Low-Band (LB) Low Noise Amplifier (LNA) design for a diversity receive module where the application is for multi-mode cellular handsets. The LB LNA covers the frequency range between 617 MHz to 960 MHz in 5 different frequency bands and a 5 Pole Single Throw (5PST) switch selects the different frequency bands where two of them are for the main and three for the auxiliary bands. The presented structure covers the gain modes from −12 to 18 dB with 6 dB gain steps where each gain mode has a different current consumption. In order to achieve the Noise Figure (NF) specifications in high gain modes, we have adopted a cascode Common-Source (CS) with inductive source degeneration structure for this design. To achieve the S11 parameters and current consumption specifications, the core and cascode transistors for high gain modes (18 dB, 12 dB, and 6 dB) and low gain modes (0 dB, −6 dB, and −12 dB) have been separated. Nevertheless, to keep the area low and keep the phase discontinuity within ±10∘, we have shared the degeneration and load inductors between two cores. To compensate the performance for Process, Voltage, and Temperature (PVT) variations, the structure applies a Low Drop-Out (LDO) regulator and a corner case voltage compensator. The design has been proceeded in a 65-nm RSB process design kit and the supply voltage is 1 V. For 18 dB and −12 dB gain modes as two examples, the NF, current consumption, and Input Third Order Intercept Point (IIP3) values are 1.2 dB and 16 dB, 10.8 mA and 1.2 mA, and −6 dBm and 8 dBm, respectively.
Electrical Properties of Two Types of Membrane Component Used in Taste Sensors
Authors: Xiang Zhanyi , Jing Yifei , Ikezaki Hidekazu , Toko Kiyoshi
Published: December 2021

The lipid phosphoric acid di-n-decyl ester (PADE) has played an important role in the development of taste sensors. As previously reported, however, the concentration of PADE and pH of the solution affected the dissociation of H+, which made the measurement results less accurate and stable. In addition, PADE caused deterioration in the response to bitterness because PADE created the acidic environment in the membrane. To solve these problems, our past study tried to replace the PADE with a completely dissociated substance called tetrakis [3,5-bis (trifluoromethyl) phenyl] borate sodium salt dehydrate (TFPB) as lipid. To find out whether the two substances can be effectively replaced, it is necessary to perform an in-depth study on the properties of the two membranes themselves. In this study, we fabricated two types of membrane electrodes, based on PADE or TFPB, respectively, using 2-nitrophenyl octyl ether (NPOE) as a plasticizer. We measured the selectivity to cations such as Cs+, K+, Na+ and Li+, and also the membrane impedance of the membranes comprising PADE or TFPB of the different concentrations. As a result, we found that any concentration of PADE membranes always had low ion selectivity, while the ion selectivity of TFPB membranes was concentration-dependent, showing increasing ion selectivity with the TFPB concentrations. The ion selectivity order was Cs+>K+>Na+>Li+. The hydration of ions was considered to participate in this phenomenon. In addition, the membrane impedance decreased with increasing PADE and TFPB concentrations, while the magnitudes differed, implying that there is a difference in the dissociation of the two substances. The obtained results will contribute to the development of novel receptive membranes of taste sensors.
Evaluation of Remote Photoplethysmography Measurement Conditions toward Telemedicine Applications
Authors: Tohma Akito , Nishikawa Maho , Hashimoto Takuya , Yamazaki Yoichi , Sun Guanghao
Published: December 2021

Camera-based remote photoplethysmography (rPPG) is a low-cost and casual non-contact heart rate measurement method suitable for telemedicine. Several factors affect the accuracy of measuring the heart rate and heart rate variability (HRV) using rPPG despite HRV being an important indicator for healthcare monitoring. This study aimed to investigate the appropriate setup for precise HRV measurements using rPPG while considering the effects of possible factors including illumination, direction of the light, frame rate of the camera, and body motion. In the lighting conditions experiment, the smallest mean absolute R–R interval (RRI) error was obtained when light greater than 500 lux was cast from the front (among the following conditions—illuminance: 100, 300, 500, and 700 lux; directions: front, top, and front and top). In addition, the RRI and HRV were measured with sufficient accuracy at frame rates above 30 fps. The accuracy of the HRV measurement was greatly reduced when the body motion was not constrained; thus, it is necessary to limit the body motion, especially the head motion, in an actual telemedicine situation. The results of this study can act as guidelines for setting up the shooting environment and camera settings for rPPG use in telemedicine.
Hygienic aspects of the impact of working conditions on the health of motor transport drivers
Authors: Shapoval Inna Valeryevna , Karimova Lilia Kazymovna , Muldasheva Nadezhda Alekseevna , Shaikhlislamova Elmira Radikovna , Stepanov Evgeny Georgievich , Khafizova Alsu Spartakovna
Published: December 2021

The profession of a motor vehicle driver is potentially dangerous due to the risk of road accidents, the acquisition of professional and professionally caused diseases, sudden death at the workplace. Taking this into account, comprehensive clinical and hygienic studies were conducted, the purpose of which was to assess the occupational risk of damage to the health of drivers on the basis of data on working conditions, occupational and professionally caused diseases, road accidents and cases of sudden death at the workplace. The working conditions, the state of health of drivers were studied, the professional and professionally-conditioned morbidity and cases of sudden death at the workplace from a common disease were analyzed. It is established that the working conditions of drivers are characterized as harmful 3 classes of 1–3 degrees (class 3.1–3.3), which cause the development of occupational diseases, mainly of the musculoskeletal system; the growth of chronic professionally caused pathology (hypertension, arthropathy, dorsopathy) and the death of the driver at the workplace from a general disease. The results of the study formed the basis for the development of preventive measures.
Foreign bodies in the nasal cavity in children
Authors: Kolesnikov Vadim Nikolaevich , Pavlenko Oksana Dmitrievna , Tikhonova Svetlana Nikolaevna
Published: December 2021

Foreign bodies in the nasal cavity in children are a fairly common reason for contacting an otorhinolaryngologist. Most foreign bodies can be removed quite easily. However, some cases are associated with significant difficulties in their searching and removing and require the use of special technical methods and general anesthesia. We present two cases of unusual foreign bodies in the nasal cavity in children.
Modern features of accounting for borrowing costs
Authors: Druzhilovskaya E.S.
Published: December 2021

Accounting for borrowing costs is undoubtedly relevant for many modern organizations. It should be noted that from this year a new federal public finance accounting standard (FAS PF) “Borrowing costs” came into force. This standard establishes updated accounting rules for borrowing costs for state (municipal) budgetary and autonomous institutions (including healthcare institutions). These rules are analyzed in this article. The research methods were analysis and synthesis, grouping method, comparison, analogy method, logical approach, systemic approach. On the basis of the research carried out, the article systematizes the types and definitions of borrowing costs provided for by the above-named federal standard. As a result, the author presents a categorical apparatus in the indicated area. In addition, the article analyzes the most important features of accounting for borrowing costs and provides examples that explain these features. The results of the study can be useful to a wide range of readers interested in the problems of modern accounting, including accounting for borrowing costs of state (municipal) budgetary and autonomous institutions (in particular, healthcare institutions), and can also be applied in the practical work of the accounting departments of these institutions and in higher education process.
Factors of the current growth of the value of investment-and-construction projects implementation in the Russian Federation
Authors: Vasilyeva E.Yu.
Published: December 2021

The author analyses the factors, which affected the volume of actual costs of investment-and-construction projects in 2020-2021 most of all. The three major factors, including price dynamics in the market of building materials, situation in the market of construction tools and equipment as well as the trends in the transport-and-logistic sphere are considered. The order of modification of the Technique of drawing up the estimate of the contract on the project, caused by the growth of costs for the used materials is described. The conclusions on the prerequisites of the rise in price of the realization value of the construction projects in current and following year are drawn.
Specifics of determination of budgeted costs at the construction enterprise
Authors: Kubrak I. A.
Published: December 2021

The artcle is dedicated to the features of the budgeted costs calculation at the construction enterprise with the use of three techniques of establishment of budgeted costs (on mechanisms, on work, on materials) which are systematized in the Technique of the use of the budget prices (costs) for the construction resources, approved by the order of the Ministry of Construction, Housing and Utilities of the Russian Federation, known as the "Technique 77". The author summarizes that the cost estimate has both general elements (the rules of regulation), and depends on the object and the subject of regulation.
Development of the algorithm of the development project management and the techniques of the assessment of the project realization effect
Authors: Bakrunov Yu. O.
Published: December 2021

The article emphasized the importance of the implementation of development projects, identified the features of the formation and significance of the team implementing development projects, defined the process of interaction of project team members, and developed an algorithm for managing a development project, and proposed a methodology for assessing the effect of its implementation.
Editorial del Vol. 1 No. 1
Authors: Veliz Briones Vicente
Published: December 2021

A pesar del control de la natalidad, el aumento poblacional mundial es eminente; consultando datos oficiales de la Naciones Unidas vemos que en el último medio siglo se ha quintuplicado, y se espera llegar en el año 2075 a los 10.000 millones de habitantes (un mundo en población más, igual al que existía en 1987). Independientemente, de los avatares demográficos, e inclusive de la capacidad de carga del planeta, la visión que debemos tener es como, entre otras cosas, podemos alimentar a ese masa poblacional humana, teniendo en cuenta que es nuestra responsabilidad como países iberoamericanos, ya que el crecimiento poblacional proviene, en su mayoría, de países en vías de desarrollo.  No obstante, no es solo una cuestión de números totales, sino de la calidad de nuestras poblaciones, ya que, hoy en día, de los 7.750 millones de personas, se estima la existencia con casi 1000 millones de personas desnutridas, y 1700 millones malnutridas, lo cual hace imperativo y de responsabilidad histórica la producción de alimentos pero nutritivos y sanos, como los productos acuícolas los cuales son señalados como unos de los más importantes para palear la alta demanda poblacional; sin embargo, nuestros cuerpos de agua sean continentales o marinos sufren, en la mayoría, intervenciones que hacen que la pesca no pueda subsanar las demandas, siendo la acuicultura parte de la solución, la cual hoy suple más de la mitad de la producción acuícola.
Páginas preliminares del Vol 1 No. 1
Authors: Editorial Equipo
Published: December 2021

Responsables de está edición y normas generales de la revista
Efecto de probióticos sobre el crecimiento de semillas de ostión del pacífico Crassostrea gigas
Authors: García Bernal Milagro , Medina Marrero Ricardo , Campa Córdoba Ángel Isidro , Barajas Frías José Delfino , Luis Villaseñor Irasema Elizabeth , Mazón Suástegui José Manuel
Published: December 2021

Se  realizó  un  estudio  en  juveniles  de  Crassostrea  gigas  para investigar el potencial efecto  probiótico de Streptomyces  spp. (cepas V4, N7 y RL8) y de una mezcla de Bacillus (BMix) teniendo como variable de respuesta su  crecimiento.  Las  bacterias  fueron  adicionadas  con  el  alimento  vivo (microalgas),  para  ser  ingeridas  por  los  ostiones  mediante  filtración.  El  diseño experimental  incluyó  cuatro  tratamientos  bacterianos:  [T1  (Streptomyces  sp. V4); T2 (Streptomyces sp. N7); T3 (Streptomyces sp. RL8); T4, una mezcla de bacilos  BMix  (Bacillus  tequilensis  YC5-2,  Bacillus  endophyticus  C2-2  y Bacillus  endophyticus  YC3-B]  y  un  tratamiento  Control  (T5)  con  solo microalgas  como  alimento.  Estas  cepas  potencialmente  probióticas  fueron suministradas a una concentración final de 1 × 106 UFC mL-1 y las microalgas (Isochrysis galbana y Chaetoceros calcitrans en proporción 1:1) a una densidad de 70-80 × 103 células mL-1). Los tratamientos T1 y T3 (Streptomyces spp. V4 y RL8,  respectivamente),  incrementaron  significativamente  el  área  y  el  diámetro teórico de la concha de C. gigas. Esto sugiere que la adición Strepromyces spp. V4  y  RL8  puede  mejorar  el  crecimiento  de  C.  gigas  durante  el  proceso  de preengorda de semillas en laboratorio.
Evaluación del crecimiento de Eucheuma isiforme (Rhodophyta, Gigartinales) en sistemas de cultivo suspendidos en la isla de Cubagua, Venezuela (sureste del Mar Caribe)
Authors: Montoya Rosas Emily Del Valle , Rosas Cabrera Jesús Alberto , Rincones León Raúl Ernesto , Narváez Rodríguez José Lorenzo
Published: December 2021

El cultivo de algas rojas constituye la más reciente expansión en la producción global de macroalgas. Las especies más cultivadas son Kappaphycus alvarezii, K. striatus y Eucheuma denticulatum, principales fuentes de materia prima para la producción de carragenina. Debido a los diferentes beneficios socioeconómicos generados por la maricultura de algas, diversos países han adoptado esta actividad como fuente alternativa de ingresos en sus comunidades costeras. Con miras a contribuir con el desarrollo de la maricultura de macroalgas en Venezuela se llevó a cabo un estudio preliminar del crecimiento de Eucheuma isiforme, una especie endémica del mar Caribe y productora de iota-carragenina. En este estudio fueron evaluados dos sistemas de cultivo suspendidos: horizontal (long line) y vertical (balsa flotante). La técnica de cultivo consistió en amarrar implantes vegetativos por medio de rafias plásticas conocidas como tie-tie a líneas principales de polipropileno de 6 mm de diámetro. El peso promedio inicial de los implantes estuvo comprendido entre 20-25 g, con una densidad de siembra de 0,06 kg.m-2 en el sistema horizontal y 0,02 kg.m-2 en el sistema vertical. El bioensayo tuvo una duración de 9 semanas entre los meses de febrero-abril 2017, registrándose una variación en el crecimiento de la biomasa a través del tiempo. La tasa diaria de crecimiento promedio (biomasa húmeda) fue 5,54 ± 0,31 % en el sistema horizontal y 6,69±0,12% en el vertical. El crecimiento de E. isiforme registrado durante este trabajo en la bahía de Charagato es alto con respecto a otras experiencias de cultivo realizadas en la cuenca del Caribe, considerándose por tanto un sitio adecuado para la maricultura comercial de macroalgas en Venezuela.
Cambios organolépticos inducidos en la ostra japonesa Crassostrea gigas con dietas de las microalgas Thalassiosira pseudonana y Tetraselmis suecica
Authors: Hakamada Mera Takeshi , Alio Mingo José Javier , Bravo Montesdeoca Guadalupe
Published: December 2021

El cultivo de ostras, particularmente de la ostra japonesa Crassostrea gigas, en el Ecuador, se muestra como una alternativa para diversificar su producción acuícola. Una manera de dar valor agregado a los moluscos bivalvos es modificar sus propiedades organolépticas o refinamiento, alimentándolos con densidades altas de microalgas. En el presente estudio, un grupo de panelistas degustadores entrenados evaluaron el impacto organoléptico de ostras Crassostrea gigas, proveniente de un cultivo en suspensión, refinándolas con las microalgas Thalassiosira pseuodonana y Tetraselmis suecica, y un grupo control mantenido en el mar, durante un periodo de 3 semanas. Transcurrida la primera semana, se evidenciaron diferencias significativas en cuanto a los 2 tratamientos y el control, las cuales se mantuvieron hasta la tercera semana. Los evaluadores pudieron discriminar las ostras alimentadas con T. pseudonana, atribuyéndoles un sabor más dulce, aroma a pescado fresco y un grado de aceptación superior. Tetratselmis suecica se caracterizó por un sabor y olor a algas; mientras que el grupo control no presentó una característica netamente definida en cuanto a sabor y olor, pero si una menor aceptación. Se concluye que una dieta especifica de microalgas aplicada por una semana, causa efectos de mayor aceptación sobre las propiedades organolépticas, tanto en sabor como en olor de las ostras, pudiendo generarles valor agregado.
Contenido Acumulado Vol. 3
Authors: Editorial Equipo
Published: December 2021

Contenido Acumulado Vol. 3
Effect of hydrogen sulfide on the characteristics of the neuromuscular synapse terminals of the rat diaphragm
Authors: Kadenov A.N. , Yakovleva O.V.
Published: December 2021

Hydrogen sulfide is one of the gas-transmitters that also performs other biological functions. The antioxidant property of this substance is one of the important ones. The research was conducted on rats of both sexes between 6 and 18 days of age. We have shown that the offspring of females injected subcutaneously with hydrogen sulfide increased the area and luminescence of nerve terminals during postnatal ontogenesis, which can be further used to level the effects of hyperhomocysteinemia on synaptic transmission.

Key words: neuromuscular synapse, fluorescent microscopy, hydrogen sulfide.
The role of disorders in the functional activity of platelets in the pathogenesis of microcirculatory disorders in patients with catarrhal gingivitis
Authors: Kitaeva V.N. , Smolkina A.V.
Published: December 2021

A comprehensive examination of patients with chronic catarrhal gingivitis and with exacerbation of chronic catarrhal gingivitis with the inclusion of indicators of the microcirculatory link of the hemostasis system was carried out. In patients with exacerbation of chronic catarrhal gingivitis, platelet aggregation activity is increased compared to that in healthy individuals. This is accompanied by a statistically significant increase in the maximum degree of aggregation, a change in the time to reach the maximum degree of platelet aggregation

Key words: platelet aggregation, catarrhal gingivitis, exacerbation of chronic catarrhal gingivitis.
The role of neuronal NO synthase in the respiratory effects of TNF-α
Authors: Klinnikova A.A. , Danilova G.A. , Aleksandrova N.P.
Published: December 2021

It was shown that an increase level of proinflammatory cytokines has a modulating effect on the reflex control of respiration. The aim of this study was to investigate the involvement of neuronal nitric oxide synthase (nNOS) in the mechanisms of the influence of an increased level of Tumor necrosis factor – α (TNF-α) on the hypoxic ventilatory response. To achieve this goal, experiments were carried out on urethane anesthetized rats with intravenous administration of TNF-α before and after pretreatment with 7-nitroindazole specific nNOS inhibitor. The hypoxic ventilation response was assessed by rebreathing with a hypoxic gas mixture before and after administration of TNF-α. We found that TNF-α decreased the ventilatory response to hypoxia. Pretreatment with nNOS inhibitor reduced respiratory effects of TNF-α.

Key words: cytokines, TNF-α, hypoxia, chemoreflex, respiration, ventilation, neuronal nitric oxide synthase.
Modern problems of regionalization of territories and human adaptation in regions with extreme natural and climatic conditions
Authors: Maksimov A.L.
Published: December 2021

The paper considers modern approaches to the zoning of territories and the selection of people for life in extreme environmental conditions, taking into account modern geopolitical challenges. It is shown that it is possible, based on the allostasis concept, to conduct not only the selection of persons with a high level of nonspecific resistance, but also to quantify the degree of extremity of environmental factors using the standard represpiration test.

Key words: adaptation, extreme conditions, selection, hypoxia, cold, rerespiration, allostatic load.
Quality of life of patients after inguinal hernioplasty by endoscopic methods
Authors: Asutaev Sh.D. , Poborskiy A.N.
Published: December 2021

A comparative analysis of the indicators of 53 men who underwent inguinal hernioplasty using the TEP (n = 20) and TAPP (n = 33) methods was carried out. Quality of life was assessed using the international questionnaire EQ-5D on the 1st day, 1 month and 12 months after surgery. Monitoring of quality of life parameters showed differences in the assessment of their condition by patients who underwent TEP and TAPP, which were most pronounced on the first day after surgery. The presence of problems during this period for all components of the EQ-5D questionnaire, to a greater extent, was associated by patients with pain / discomfort in the operation area. The latter were maximally manifested in the majority of those who underwent TAPP (64%), which also affected their lower assessment of their health status. The revealed differences disappear within a month after the interventions and are absent 12 months after the operation.

Key words: quality of life, inguinal hernioplasty, endoscopic methods.
Assessment of the functional state of military men with different types of autonomic regulation in the midland’s conditions
Authors: Satarkulova A.M. , Melisova B.M. , Aisaeva Sh.Yu.
Published: December 2021

The article presents the results of assessment and dynamic control over the functional state of military men in the midlands conditions. Depending on the initial type of autonomic regulation, groups with vagotonic (24%), sympatotonic (26%) and normotonic (50%) directions of regulatory processes were identified. It has been established that the state of optimal working voltage with more economical functioning of regulatory mechanisms is characteristic of carriages; for sympathotonics - an overstrain of regulatory mechanisms, and for normotonics - a moderate tension of regulatory systems with the mobilization of the functional reserves of the body.

Key words: heart rate variability, functional state, types of autonomic regulation, midlands, military men.
Vascular-tissue relations in the lungs in experimental superinvasive opisthorchiasis
Authors: Shvedsky M.S. , Solovyov G.S. , Matvienko V.V. , Shidin V.A. , Solovyova O.G. , Istomina O.F.
Published: December 2021

Structural changes in the lungs in superinvasive opisthorchiasis at various stages of invasion were studied. The morphology of permanent epithelial proliferation at the initial stage and their decrease in the late period were revealed. With the formation of granulomas in the interstitial tissue of the respiratory organs, with changes in the chronic period towards the formation of sclerotic foci.

Key words: superinvasive opisthorchiasis (CO), metacercariae, acinus, terminal bronchioles (TB), cell infiltrates, pneumocytes.
Comparative characteristics of the main sanogenetic mechanisms in large laboratory animals (pigs) with acute blood loss and after infusion of an isotonic colloidal solution based on dextran and an isotonic solution based on polyglucin in conditions of general external cooling
Authors: Shvetc A.O. , Shperling I.A. , Krupin A.V. , Romanov P.A. , Matveeva N.N.
Published: December 2021

The experiment was carried out on male pigs, which in the operating room were simulated with acute blood loss (air temperature 23oC). Then the animals were placed in a climatic chamber (minus 50 ° C) for 10 minutes. Then the temperature in the climatic chamber was raised to minus 10 ° C and the introduction of the test solutions to the animals began. It was found that in both groups there were similar indicators of blood pressure. The heart rate and respiratory rate in animals in the group with the experimental solution based on polyglucin derivatives were lower than in the group with the solution based on dextran.

Key words: external general cooling, pigs, blood pressure, heart rate, respiratory rate, infusion solution.
he specifics of posture formation among schoolchildren living in the city of Khanty-Mansiysk against the background of undifferentiated connective tissue dysplasia
Authors: Shevnin I.A. , Ragozin O.N. , Ragozina O.V. , Ilyushchenko N.A. , Jafarova B.Z.
Published: December 2021

Undifferentiated forms of DST are widespread among children living in Khanty-Mansiysk, in connection with which it is relevant to assess the influence of this pathology on the formation of posture in schoolchildren of the North. Determination of the type of posture and the identification of stigmas of dysembryogenesis was carried out in 208 schoolchildren of the city of Khanty-Mansiysk. Posture types were divided into: normal, round, flat and stooped. Participants with the number of stigmas from 0 to 5 were allocated to the comparison group (n = 66), the rest (6 or more) made up the study group (n = 143). A card was entered, including 43 hair dryers. The study found that the incidence of UCTD among children in the Khanty-Mansi Autonomous Okrug-Yugra is noticeably higher than among those living in temperate latitudes and has a negative effect on the formation of posture.

Key words: North, posture, physical development, undifferentiated connective tissue dysplasia.
Temporary cardiointerval organization with varying degrees of acute normobaric hypoxia in a healthy person
Authors: Bocharov M.I.
Published: December 2021

The influence of acute normobaric hypoxia (ANH) on the male heart chronotropic effects was studied. Thus, a mild degree of ANH (14.5 % O2, 20 min), causing a decrease in blood oxygenation by 6.3 abs. %, accompanied by an initial (by 5 min) decrease in the RR and QT intervals. The average degree of ANH (12.3% O2) leads to a decrease in blood oxygenation by 19.7 abs. %. At the same time, in inverse relationship to the developing hypoxemia, RR and QT significantly decrease. Corrected values (Pc, PQc, QRSc, QTc) increase during the action period of an average degree of hypoxia, indicating an increase in the proportion of atrial contraction time, atrioventricular conduction of excitation and electrical ventricular systole in the total RR duration, which, apparently, provides optimal systolic heart effect.

Key words: human, hypoxia, blood oxygenation, cardiointervals.
External respiration and gas exchange in conditions of maximum load at different levels of the body's aerobic capacity
Authors: Vinogradov S.N.
Published: December 2021

The study of the characteristics of the reactions of the links of external respiration and gas exchange at various stages of performing a step-increasing load and at maximum load with various aerobic capabilities of the body was carried out. The data obtained indicate that the level of aerobic capabilities of the body determines the characteristics of the reactions of the links of external respiration and gas exchange at various stages of performing a step-increasing load and at maximum load.

Key words: functional reserves of organism, gas transportation system, maximum oxygen consumption, aerobic capacity of organism, gas exchange.
The role of ENOS polymorphism (C774T) in the progression of acute peritonitis and the formation of complications
Authors: Vlasov A.P. , Al-Kubaysi S.S. , Ali Fuad F.A. , Al-Anbari S.T. , Fedotov B.A.
Published: December 2021

In order to determine the role of ENOS (C774T) gene polymorphism in the progression of acute peritonitis and the formation of complications, a clinical and biochemical study of 40 patients with acute peritonitis was conducted. As a result of the study, it was proved that the early period of acute peritonitis is characterized by the development of endogenous intoxication, intensification of oxidative phenomena, hypercoagulation of the homeostasis system and inhibition of fibrinolysis, and in patients with acute peritonitis, carriers of the pathological TT genotype of the endothelial nitric oxide synthase gene, more pronounced deviations of homeostatic parameters are observed.

Key words: acute peritonitis, genotype, DNA diagnostics, genetic testing of genotypes.
Prognostic value of endotoxicosis criteria in the diagnosis of acute renal injury
Authors: Vlasov A.P. , Ryazantsev V.E. , Muratova T.A. , Volkova M.V. , Stepanov N.Yu. , Mashnin I.V.
Published: December 2021

In order to find informative statically significant laboratory criteria for endotoxicosis in the diagnosis of acute renal injury, a clinical and biochemical study of 40 patients with acute renal injury developed against the background of renal urological and extrarenal surgical pathology was conducted. The results of the study demonstrate pronounced changes in the mechanisms of antioxidant protection that develop in patients with acute renal injury. Deviations from the initial level of the studied criteria are interrelated with many links of pathogenesis, where one of the central links is ischemia of the renal parenchyma. The progression of endogenous intoxication, taking into account the data obtained, confirmed by a decrease in prooxidant protection contributes to the progression of intrarenal changes, aggravating functional changes in renal and extrarenal injuries.

Key words: significance of endotoxicosis criteria, acute renal injury, endotoxicosis, serum creatinine, glomerular filtration rate.
Study of the energy supply of muscular activity in the Cooper test among sportsmen-gamers according to the individual heart rate response to the load
Authors: Gorbaneva E.P. , Mitsulina M.P. , Ryabchuk Yu.V.
Published: December 2021

In this study, using the example of the Cooper test, pulse zones were identified in percentage ratio, which allow indirectly judging the contribution of a particular energy supply system for each athlete during cyclic work.

Keywords: Cooper's test, energy supply, athletes-game players, pulse zones, heart rate monitoring, Polar.
The role of prostaglandins in the realization of respiratory effects of TNF-α in case of hypoxia
Authors: Danilova G.А. , Klinnikova A.A. , Aleksandrova N.P.
Published: December 2021

At the present time very little is known about interactions between systemic inflammation and control of respiration. The aim of this study was to compare the respiratory effects of the main inflammatory cytokine TNF - α before and after pretreatment with diclofenac, a nonspecific cyclooxygenase (COX) inhibitor.

In experiments on anesthetized, tracheostomized rats, pneumotachometry method was used to measure peak airflow and respiratory rate. The ventilatory response to hypoxia was investigated by the rebreathing method. It is shown that an increase in the systemic level of TNF – α causes a significant increase in the minute volume of respiration, tidal volume, the average speed of the inspiratory flow. In contrast the slope of the hypoxic ventilatory response decreased after administration of TNF-α. Diclofenac pretreatment eliminated these respiratory effects of TNF - α. The data indicate that the ability of TNF - α to enhance basal ventilation and to reduce the ventilatory hypoxic response is mediated by the cyclooxygenase pathway.

Key words: tumor necrosis factor – α, hypoxia, prostaglandins, peripheral chemoreception, respiration.
Forecasting the radiation background in the territories of Kazakhstan located near the uranium mining industries
Authors: Ismailova A.A. , Nurbaeva N.A.
Published: December 2021

A significant part of the territory of Kazakhstan is characterized by a high natural background radiation of soils and rocks, the spread of natural ground and underground waters with high concentrations of radionuclides in the regions of uranium, thorium and rare metal ore provinces and regions. Therefore, conducting high-quality radio monitoring of the state of the environment using modern information systems will make it possible to predict the background radiation in a timely manner and outline measures to reduce environmental risks to the health of the nation as a whole.

Key words: radioecology, monitoring, life safety, radionuclides, national health.
SELECTION OF A RATIONAL RECIPE OF LIGHTWEIGHT CONCRETE ON A MIXTURE OF CERAMSITE GRAVEL, NATURAL CRUSHED STONE AND GRANULAR SLAG
Authors: Chernil'nik A. , El'shaeva D. , Zherebtsov Y. , Dotsenko N. , Samofalova M.
Published: December 2021

In conditions of dense urban development and a variety of engineering and geological conditions, the use of concretes with a combined aggregate of a rationally selected composition will solve the existing problem of reducing the mass of reinforced concrete structures of buildings and structures and maintaining the required strength and deformability. In this paper, studies have been carried out on the choice of a rational formulation of lightweight concrete based on expanded clay gravel, natural crushed stone and granulated blast furnace slag by varying the volume content of porous coarse aggregate and the volume content of fine aggregate in relation to the mixture. In total, 9 series of prototypes and 1 series of control samples are manufactured and tested. One series of samples includes three cubes with dimensions of 10x10x10 cm. All samples are tested in terms of density and compressive strength, the coefficient of constructive quality is determined. The results of the study shows that the introduction of expanded clay gravel into the composition of heavy concrete instead of part of the dense coarse aggregate and the replacement of the fine dense aggregate with granular blast furnace slag leads to an increase in the structural quality factor, that is, a decrease in the compressive strength of concrete is compensated for by an even more significant decrease in the density of the material, and means weight reduction. The increase in the coefficient of constructive quality of concrete based on expanded clay gravel, natural crushed stone and granulated blast-furnace slag in comparison with the control composition is 15.6 %.
DOMESTIC AND FOREIGN TYPES OF REDEVELOPMENT OBJECTS FOR HOUSING
Authors: Ogienko E.
Published: December 2021

Manufacturing has historically been the driving force behind economic growth and structural change. During the financial and economic crisis, governments in Europe provided short-term assistance to industries that had fallen into disrepair by converting them into market-oriented industries (such as steelmakers and car manufacturers). As cities grow and the density of megacities increases, the need for their "renewal" began to appear, which is characterized by the transformation of non-functional buildings and old abandoned buildings for the purpose of further operation. The state and private organizations were interested in the transformation of such territories and actively invest in these projects. Industrial complexes are transformed into areas with residential apartment buildings and offices, their own social infrastructure, transport, entertainment reflecting the needs of modern society. In the future, urban areas can benefit greatly from new opportunities. All over the world, industrial territories are an integral part of cities. The article discusses the experience of reconstruction of industrial zones in Russia and abroad. The industrial heritage is adapting to the new context of the city, using the principles of sustainability, economy and aesthetics