bluuebunny/crossref_metadata_2025 huggingface dataset:
Tindak Tutur Direktif Tokoh Utama dalam Novel Laut Bercerita Karya Leila S. Chudori
Authors: Putra Fajar Dwi Nanda , Amir Amril
Published: May 2023

Penelitian ini bertujuan untuk mendeskripsikan bentuk tindak tutur direktif dan strategi bertutur tokoh utama dalam novel Laut Bercerita karya Leila S. Chudori. Data penelitian dikumpulkan melalui metode dokumentasi dan dianalisis melalui tahapan reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan 34 tindak tutur direktif dan 37 strategi bertutur yang digunakan tokoh utama. Tindak tutur direktif meminta dan strategi bertutur terus terang tanpa basa-basi adalah yang paling banyak ditemukan, masing-masing sebanyak 18 dan 22.
Analisis Majas dan Diksi pada Lagu Amin Paling Serius yang Dipopulerkan Sal Priadi dan Nadin Amizah
Authors: Karmila Karmila , Abdurahman Abdurahman
Published: May 2023

Saat ini lagu berkembang dengan sangat cepat. Hal ini dapat dilihat dari banyaknya lagu-lagu baru yang dipopulerkan oleh musisi baru. Salah satunya adalah lagu Amin Paling Serius yang dipopulerkan oleh Sal Priadi dan Nadin Amizah. Karena lirik lagu yang sangat menarik serta kepopuleran lagu ini, penulis tertarik untuk meneliti gaya bahasa dan diksi dalam lagu ini. Jenis penelitian ini adalah penelitian kualitatif dengan metode deskriptif. Pada penelitian ini digunakan pendekatan stilistika. Kata, frasa, dan kalimat merupakan bentuk data yang didapatkan dalam penelitian ini. Data dalam penelitian ini berasal dari lirik lagu Amin Paling Serius yang dipopulerkan oleh Sal Priadi dan Nadin Amizah. Pengumpulan data dalam penelitian ini menggunakan teknik analisis dokumen yang menjadikan peneliti sendiri yang menjadi instrumen kuncinya. Penganalisisan data dalam penelitian menggunakan teknik analisis jalinan atau mengalir yang terdiri dari beberapa tahapan yaitu mengumpulkan data, menyajikan data, dan menarik kesimpulan. Hasil penelitian ini yaitu ditemukan 26 gaya bahasa dan 39 diksi dalam lagu Amin Paling Serius yang dipopulerkan oleh Sal Priadi dan Nadin Amizah. Penelitian ini sangat direkomendasikan bagi orang-orang yang senang mendengarkan lagu Amin Paling Serius  agar lebih mengenal tentang lagu ini.
The Effect of BPR Composite Value of Governance Self Assessment on BPR Performance (Case Study of BPR in Bekasi Regency and City)
Authors: Juniasti Riwandari
Published: May 2023

The purpose of this research is to analyze and determine the effect of the composite value of governance self-assessment on BPR performance in the Bekasi Regency and City. The research method utilizes a quantitative approach with a causal design. The study used one independent variable, namely the composite value and five dependent variables, namely (NPL, ROA, BOPO, LDR, Cash Ratio). This type of data collection used secondary data from the Bekasi Regency and City BPR in the period from 2018 to 2020. The data analysis method used simple regression analysis with the help of the Eviews 10 program. The results in this study state that 1) composite values ​​had no effect on NPL. 2) the composite value had no effect on ROA, 3) the composite value had no effect on the BOPO, 4) the composite value had no effect on LDR, 5) the composite value had no effect on the Cash Ratio
Association Between Quality of Sleep and Self- Reported Health with Burnout in Employees: Does Increasing Burnout Lead to Reduced Work Performance Among Employees
Authors: Bhatti Muhammad Awais , Alnehabi Mohammad
Published: May 2023

Objectives: To determine the effect of quality of sleep (SL) and self-reported health (SRH) on burnout (BO) and whether burnout, in turn, impacts work performance (WP) among employees of the Higher Educational Institutions (HEI's). Methods: Data was collected using the
survey method using questionnaire items adapted from the literature. The final sample consisted of 138 employees. A two-step procedure was conducted using AMOS by first employing confirmatory factory analysis followed by structural equation modeling. Results: The results supported the
hypotheses proposed in the study as SL positively and significantly impacted employee burnout. Similarly, SRH was found to have a significant positive association with BO while BO significantly and negatively affected WP. Conclusion: Employees' work performance reduces with increased
burnout which is aggravated due to poor sleep quality and self-reported health; hence, the study provides insightful contribution for managers and workers to focus on improving work performance by reducing burnout.
An Evaluation Index System for Core Competencies of Specialist Nurses in Pediatric Emergency Care
Authors: Tao Yi , Jiang Xiaoping , Li Wenjing , Feng Mei , Zhang Li
Published: May 2023

Objective: We aimed to construct an evaluation index system for the core competencies of specialist nurses in pediatric emergency care using the Delphi method. Methods: We preliminarily defined 3 levels of evaluation indices for the core competencies in this nursing specialty
through literature review and qualitative analysis. We conducted 2 rounds of expert consultation (using the Delphi method) to screen, revise, and finalize the indices. Results: Two rounds of inquiry sufficiently defined the evaluation index system for the core competencies. The evaluation
index system consists of 70 tertiary indices, 17 secondary indices, and 6 primary indices. The authority coefficients of the 2 rounds were 0.859 and 0.876, respectively, and the effective response rates of both rounds was 100%. Conclusion: The proposed evaluation index system is reliable,
comprehensive, and professional, providing a quantifiable basis for the evaluation and appraisal of the core competencies in this area of nursing specialization.
Prevalence of and Factors Associated with Undernutrition in Southern Bangladesh: A Cross-Sectional Study
Authors: Haque Md. Uzzal , Hasan Md. Tarek , Rahman A.M. Shihabur , Hasan Md. Mohibul , Islam Shahriar , Chouduri Aktar Uzzaman
Published: May 2023

Background: Undernutrition is one of the main causes of child mortality and morbidity in Bangladesh. This study aimed to assess the prevalence and determinants of undernutrition among children aged six to fifty-nine months in the Jashore and Khulna districts of southern Bangladesh.

Methods: The random sampling technique was used to select 400 children of 6–59 months of age. Data were collected through face-to-face interviews using a structured questionnaire and anthropometric measurements. The weight and height of children were taken using a digital weighing scale, measuring tape, and stadiometer following standard protocols. Children’s undernutrition was estimated by stunting, wasting, and being underweight. The logistic regression analyses were done to assess the factors associated with undernutrition.

Results: The prevalence of stunting was 57% (95% CI: 52.1–61.8) which was positively associated with diarrhea, illiterate mothers, absence of sanitary latrine, and no antenatal care (ANC). The wasting prevalence was 13% (95% CI: 10.1–16.7) which remained directly associated with family size (≥6 members), low household income, and family planning methods. The rate of prevalence of underweight was 27.8% (95% CI: 23.6–32.3) which was significantly associated with illiterate mothers, low household income, family size (≥6 members), lack of pure drinking water, and complementary feeding started before six months. Stunting was more prevalent (74.7%) in the age group of 42–53 months compared to other groups, and boys (60.7%) were more stunted than their counterparts (52.9%).

Conclusions: The magnitude of childhood undernutrition was high among the studied participants. Nutritional interventions should be implemented on the basis of significant factors in the local context to tackle this problem in Bangladesh effectively.
Influence of Nutrition Knowledge on the Association between Maternal Nutrition and Birth Outcomes
Authors: Mehboob Arshi , Sanghi Divya
Published: May 2023

Maternal undernutrition is a complex condition that arises from various factors, including social, cultural, psycho-social, biological, and ecological factors. The intergenerational consequences of chronic malnutrition, starting with mothers and their children, account for a significant proportion of infant deaths, cognitive disability, and reduced productivity in adulthood. Therefore, having nutritional knowledge throughout pregnancy is crucial for better risk assessment of undernutrition and healthy pregnancy outcomes. The study examined whether trimester-specific nutrition education and awareness could significantly impact the relationship between maternal nutrition and birth outcomes and found that this association was stronger in women with higher levels of nutrition knowledge. As a result, a food-based approach that is both low-cost and high-nutrition can help meet the specific nutritional requirements of pregnancy, alter certain nutrients that target fetal metabolic vulnerabilities, or enhance fetal growth and development in the migrant population. The review explores recent research and discusses how nutrition literacy and knowledge influence pregnancy and birth outcomes, providing an overview of the current understanding of maternal nutritional trimester-specific needs and highlighting areas that still require further study. The findings emphasize the importance of considering diet diversity and peer support during pregnancy, considering the impact that nutrition knowledge has on pregnancy outcomes.
Ageing with apps: A Foucauldian study exploring older people’s use of apps in managing their physical health
Authors: Bavngaard Martin
Published: May 2023

This article explores the incorporation of mobile applications in older people’s physical health management through the lens of Foucault’s concepts on self-governance. Based on ten interviews with older Danes, the article posits that physical health management practices constitute practices of self-governance, involving participants’ attunement to both physical activity and bodily phenomena, which are both facilitated and optimized through app-based self-tracking. The findings align the rationales driving participants’ efforts with the trajectory of the governmental concept of active ageing. Using apps thus becomes intertwined with participants’ efforts towards ageing successfully, consequently taking on a dual function: Apps strengthen the adherence to norms of conduct for achieving an optimal ageing process by allowing for ubiquitous self-monitoring and self-assessment. Simultaneously, I argue that apps may also act as a gatekeeper, as lacking the technical competencies to efficiently use apps hinders effective health management and thus clashes with efforts conforming to active ageing.
Data sense-making and communicative gaps on sundhed.dk
Authors: Mahnke Martina Skrubbeltrang , Petersen Matilde Lykkebo , Nielsen Mikka
Published: May 2023

This paper examines personal experiences of digital health data on the Danish eHealth platform sundhed.dk. Taking a patient’s view, the paper understands data sense-making as an embodied communicative practice. The empirical analysis, consisting of 24 purposefully sampled interviews, is brought together with the conceptual framework describing and unpacking the ambivalences to be found in digital health data experiences into themes of data ambivalence, emotional ambivalence, communicative ambivalence and identity ambivalence. This in-depth empirical description of patients’ ambivalent experiences contributes to a more nuanced understanding of the profound changes digital health data is having on a patients’ everyday lives. In particular, it emphasizes the communicative challenges arising from the constant availability of digital health data anytime, anywhere, and calls for further research into the new and unfamiliar communicative situations in which patients are placed and forced to navigate in.
Introduction: The entanglements of media and health in everyday life
Authors: Grønning Anette , Sandberg Helena
Published: May 2023

Just as the title above suggests, it is difficult to address health issues without considering the role of the media and everyday life; the time and space when health is produced and cared for or put at risk and exposed. In the introduction to this special issue, ‘Media and health in everyday life’, we will discuss the three components of the theme. We will offer some definitions, but also problematise the conceptual underpinnings and highlight the intertwinement of the three. We set off by reflecting on health. Then we will engage with ideas around the notion of everyday life. In the final section, we add the component of the media before we present and summarise the nine contributions to the special issue and clarify to what extent they add to our understanding of the theme.
Perception/réception de la démocratie dans le prisme de la choura chez les islamistes
Authors: Fadil Mohamed
Published: May 2023

L’étude proposée dans cet article a pour objet le processus de la réception de la démocratie chez les islamistes qui s’étend du rejet à l’adoption conditionnelle. Plus précisément, elle vise à explorer la configuration du concept de la choura dans ce processus. Une méthode interdisciplinaire combinant sociologie des religions et théologie est apparue comme l’avenue la plus propice afin de mettre en rapport la dimension religieuse et la dimension politique de cette question dans une perspective historique diachronique. Privilégiant une approche socio-analytique comparative et le recours à l’analyse de contenu et de l’étude de cas, l’étude se penche sur deux corpus idéologiques élaborés par deux grandes figures du paysage islamiste au Maroc. Premièrement, Abdessalam Yassine (1928-2012), fondateur, ex-guide suprême et principal théoricien deǧamāʿaẗ al-ʿadl wa al-iḥsān(Groupe de l’équité et de la bienfaisance), comme représentant du camp rejetant la démocratie en faveur de la choura. Deuxièmement, Ahmed Raissouni (1953-), président (1996-2003) deḥarakaẗ al-tawḥid wa al-islāḥ(Mouvement de l’unicité et de la réforme), matrice et groupe de prédication lié auḤizb al-ʿadāla wa al-tanmiya(Parti de la justice et du développement : parti d’idéologie islamiste qui a siégé au pouvoir gouvernemental au Maroc durant la période 2012-2021), comme représentant du camp de réconciliation, bien que conditionnelle, entre la choura et la démocratie.
Awe of What a Body Can Be: Disability Justice, the Syllabus, and Academic Labour
Authors: Dorrance Jess , Havard Julia , Luna Caleb , Young Olivia K.
Published: May 2023

This article explores the practice of critically and lovingly manifesting access in syllabus construction and examines how axes of oppression shape our classrooms via the syllabus. We are a collective of multi-racial queer and trans disabled academics writing from our personal experiences and our engagements with performance studies and Disability Justice. We argue that the academy must shift from discussions of accommodations to access, surface questions of Disability Justice and teaching labour in graduate school and higher education at large, and offer a series of questions for teachers to examine their approach to disability in their classrooms.
Performativity, Possibility, and Land Acknowledgments in Academia: Community-Engaged Work as Decolonial Praxis in the COVID-19 Context
Authors: Roth Sammy , Blu Wakpa Tria
Published: May 2023

At the intersection of dance, performance, and Indigenous studies, this essay reflects on how an assistant professor at the University of California, Los Angeles—with the support of a graduate student researcher—has aimed to put an Indigenous land acknowledgment into praxis through community-engaged work. In academic settings, land acknowledgments are often given prior to an event and may circulate on written materials, such as event programs, syllabi, letterhead, departmental and research centre websites, and email signatures. Based on Indigenous protocols, these statements typically identify the original Indigenous peoples whose land the university currently occupies; they should also be created in collaboration with Indigenous leaders from the tribe(s). Indigenous land acknowledgments can be important because they directly combat the injustice of settler-capitalist, mainstream discourses that often obscure Indigenous peoples and practices or relegate them to the historical past. Yet, Indigenous people and Indigenous studies scholars have critiqued non-Native land acknowledgments as “performative.” Without direct material benefits to Indigenous peoples, land acknowledgments can serve as empty gestures that “perform” university commitments to anti-racism, equity, diversity, and inclusion. In contrast to the “performative” as an empty gesture, the fields of performance and dance studies frequently theorize “performativity” as a material action that can function both hegemonically and subversively. This essay argues that community-engaged research, teaching, and service—which the authors view holistically—are key ways to begin or further the process of putting a university’s land acknowledgment into action.
Un/Commoning Pedagogies: Forging Collectivity Through Difference in the Embodied Classroom and Beyond
Authors: Chapman Dasha A. , Dellecave J , Jones Adanna Kai , Kivenko Sharon Freda , LaMothe Mario , Weidman Lailye , Zabriskie Queen Meccasia
Published: May 2023

Un/Commoning Pedagogies Collective are seven dancer-scholars who centre embodied anti-racist praxis in our teaching across the fields of anthropology, sociology, African American and Africana studies, gender, sexuality and women’s studies, dance, and performance studies. Since 2019, the Un/Commoning Pedagogies Collective has engaged in consistent, process-based collaboration around teaching, scholarship, movement practice, and collegiality. We have co-authored essays, facilitated workshops, and given talks and performances. We also share syllabi, strategies, stories, milestones, failures, resources, and friendship. This writing is rooted in our ongoing collaborations and documents a co-generation of knowledge about the possibilities and tensions of teaching with and through our full-bodied selves. Moving beyond the syllabus, we offer you a glimpse into our concerns, commitments, experiences, and strategies as movement educators. We invite you to participate with us in a process of un/commoning pedagogy through embodied practice, dialogue, and reflection.
Bathtub Dramaturgy: An Experimental Syllabus for Theatre and Performance Studies Classrooms
Authors: Edmonson Chloë Rae
Published: May 2023

This annotated syllabus proposes an undergraduate course designed to develop dramaturgical methods around a common theme. While the course focuses on performances in and around bathtubs, the ultimate goal of this essay is to put forward methods that can be applied across an expansive range of theatre and performance studies topics. Each unit in the proposed course explores a different facet of dramaturgical practice with corresponding assignments that challenge students to practise essential research, writing, and communication skills. These assignments culminate in a final project: the presentation of students’ own devised bathtub performances. This syllabus, aiming toward a restorative pedagogy, imagines a future in-person classroom where students can collectively explore the relationship between public and private through bathtubs as a microcosm for the complexity of human experience.
Sobre migraciones, fetichismo de los papeles y biopoder
Authors: Creus Amalia
Published: May 2023

Una de las muchas cuestiones que enmarcan la experiencia de las personas migrantes en Europa es la multiplicidad de marcos legales y regulatorios dirigidos a controlar y administrar su entrada y permanencia en territorio europeo. La gran cantidad de instrumentos legislativos generados con ese objetivo han colaborado en la producción y reproducción de dinámicas que hacen de la legalidad (así como de sus límites y márgenes) una problemática central de toda la cuestión migratoria.
Innovación cuántica: ¿la próxima ola de transformación digital?
Authors: Canals Agustí
Published: May 2023

Los ordenadores cuánticos reciben cada vez más atención en los medios de comunicación, con la promesa de convertirse en una revolución en la computación y las comunicaciones digitales. Actualmente, no se puede saber seguro si esta promesa se cumplirá, pero sí que es posible hacerse una idea de qué rumbo podría tomar. El objetivo de este artículo es dar una breve panorámica de las tecnologías de la información cuántica y de sus posibilidades de futuro. Tras un resumen conciso de los cimientos de la computación cuántica y del estado actual de la tecnología, se lleva a cabo un repaso de los principales ámbitos en los que la tecnología puede dar lugar a innovaciones que mejoren sustancialmente las prestaciones de la tecnología actual. Finalmente, se apuntan algunos posibles efectos del desarrollo de la computación cuántica en la economía y la sociedad actuales.
Las palancas del éxito en la transformación digital
Authors: Margarit Elisabeth
Published: May 2023

La digitalización es, actualmente, una de las principales prioridades de las empresas y entidades del mercado español. Entendiendo la transformación digital como ‘la transformación del negocio basada en las tecnologías digitales’, en este artículo desarrollamos un aspecto clave para garantizar su éxito: cuidar especialmente al empleado, guiando la evolución del cambio cultural de la organización hacia una cultura digital que permita situar al cliente en el centro. Solo mediante un enfoque metodológico y planificado es posible acompañar a los empleados en este proceso.
Innovando en Marketing. Metaverso, un análisis 360
Authors: Méndez-Aparicio M. Dolores , Jiménez Zarco Ana Isabel , Izquierdo-Yusta Alicia
Published: May 2023

Desde que Mark Zuckerberg anunció en septiembre de 2021 el cambio de nombre de Facebook a Meta y presentó su visión del metaverso, no han cesado las especulaciones en el mundo del marketing sobre su impacto en los consumidores, y en las marcas y las relaciones que los unen. Sobre la base de la realidad virtual y gamificación, el metaverso se presenta como una visión holística de vida, donde a través de su avatar, el consumidor protagonista descubre nuevas necesidades en un mundo virtual y paralelo modelado a su antojo. Más que una incubadora de ideas de marketing para las marcas, el nuevo universo supone un mundo de especulación en el que el entorno y la sociedad podrán inventar, construir o reproducir su realidad. Es decir, podrán relacionarse, comprar y trabajar. En definitiva, vivir.
Indigeneity and Indigenous Politics: Ground-breaking Resources
Authors: Ioris Antonio A. R.
Published: May 2023

The purpose of this article is to relate the very important question of the autonomy of indigenous peoples to freely make decisions about their life with the notion of indigeneity, reconceptualised as a socially constructed and deeply contested resource. Resources are more than mere static assets or quantities of matter waiting to be measured, explored or protected. Something becomes a resource through joint processes of quantification, valuation, and normalisation. Along these lines, indigeneity is not just the ascertainment of something or someone in relation to ‘somewhat else’, but a nexus of indigenous peoples’ self-realisation and political intervention. To be indigenous is to exist politically in space and in relation to antagonist forces and processes that constantly downgrade their ethnic and social condition. Indigeneity is, thus, a resource that presupposes the value and the fight for their rights and for other (so-called) indigenous resources found in their lands. The main contribution here is the claim that indigeneity is a ground-breaking resource and a reaction formulated in the interstices of the old and new machineries of market-oriented coloniality. Indigeneity is reinterpreted as a special, highly politicised resource that directly and indirectly opposes processes of world grabbing and the appropriation of other territorialised resources from indigenous areas. It is concluded that indigeneity, as a resourceful resource, has become a key factor in the process of external and internal recognition, which galvanises political mobilisation and instigates novel forms of interaction. What makes indigenous peoples more and more unique is also what makes them share a socio-political struggle with allied, subaltern social groups.
Brownian dynamics simulation of electrical properties of KcsA potassium ion channel
Authors: Gao Ming-Zhu , Liu Chun-Liang , Wang Hong-Guang , Li Yong-Dong , Lin Shu , Zhai Yong-Gui ,   Key Laboratory of Advanced Science and Technology on High Power Microwave, Northwest Institute of Nuclear Technology, Xi’an 710024, China,   Key Laboratory for Physical Electronics and Devices of Ministry of Education, School of Electronic Science and Engineering, Faculty of Electronic and Information Engineering, Xi’an Jiaotong University, Xi’an 710049, China
Published: May 2023

As one of the regulators of cationic concentration in cells, potassium channels play an important role in the depolarization and repolarization of nerve cell. KcsA (K+ conduction and selectivity architecture) channel is simple and has the commonness of potassium ion channel, which is often used as a template for potassium channel research. In this paper, Brownian dynamics (BD) method is used to simulate the electrical characteristics of the actual KcsA potassium channel systematically. The potential mean force (PMF) of ions in the channel under electrostatic field, the current-voltage characteristic curve of symmetric solution and asymmetric solution, the ion concentration distribution curve in the axial direction of the channel, and the conduction-concentration curve are obtained. The results show that the selectivity filter region of KcsA potassium channel blocks the passage of Cl– basically, showing a special selection characteristic of the passage of K+, that its current-voltage curve presents a basically linear distribution, and that the conductivity-concentration curve presents a trend of first increasing and then flattening. The basic characteristic is consistent with the experimental phenomenon. In addition, the influence of the THz field on the channel K+ current is also simulated and analyzed. Compared with applying only the same amplitude electrostatic field, the selected terahertz field of 0.6 THz, 1.2 THz, and 5 THz can reduce the PMF by affecting the interaction potential energy between ion pairs, thereby increasing the K+ current. The research in this paper not only deepens the understanding of the regularity of KcsA potassium ion channels, but also provides a new idea for studying other types of ion channels and the influence of terahertz field on the characteristics of ion channels.
Approximating missing epidemiological data for cervical cancer through Footprinting: A case study in India
Authors: Man Irene , Georges Damien , Bonjour Maxime , Baussano Iacopo
Published: May 2023

Local cervical cancer epidemiological data essential to project the context-specific impact of cervical cancer preventive measures are often missing. We developed a framework, hereafter named Footprinting, to approximate missing data on sexual behaviour, human papillomavirus (HPV) prevalence, or cervical cancer incidence, and applied it to an Indian case study. With our framework, we (1) identified clusters of Indian states with similar cervical cancer incidence patterns, (2) classified states without incidence data to the identified clusters based on similarity in sexual behaviour, (3) approximated missing cervical cancer incidence and HPV prevalence data based on available data within each cluster. Two main patterns of cervical cancer incidence, characterized by high and low incidence, were identified. Based on the patterns in the sexual behaviour data, all Indian states with missing data on cervical cancer incidence were classified to the low-incidence cluster. Finally, missing data on cervical cancer incidence and HPV prevalence were approximated based on the mean of the available data within each cluster. With the Footprinting framework, we approximated missing cervical cancer epidemiological data and made context-specific impact projections for cervical cancer preventive measures, to assist public health decisions on cervical cancer prevention in India and other countries.
Homeostatic control of an iron repressor in a GI tract resident
Authors: Wang Yuanyuan , Mao Yinhe , Chen Xiaoqing , Huang Xinhuang , Jiang Zhongyi , Yang Kaiyan , Tian Lixing , Jiang Tong , Zou Yun , Ma Xiaoyuan , Xu Chaoyue , Zhou Zili , Wu Xianwei , Pan Lei , Liang Huaping , Zhong Lin , Chen Changbin
Published: May 2023

The transition metal iron plays a crucial role in living cells. However, high levels of iron are potentially toxic through the production of reactive oxygen species (ROS), serving as a deterrent to the commensal fungus Candida albicans for colonization in the iron-rich gastrointestinal tract. We observe that the mutant lacking an iron-responsive transcription factor Hap43 is hyper-fit for colonization in murine gut. We demonstrate that high iron specifically triggers multiple post-translational modifications and proteasomal degradation of Hap43, a vital process guaranteeing the precision of intestinal ROS detoxification. Reduced levels of Hap43 de-repress the expression of antioxidant genes and therefore alleviate the deleterious ROS derived from iron metabolism. Our data reveal that Hap43 functions as a negative regulator for oxidative stress adaptation of C. albicans to gut colonization and thereby provide a new insight into understanding the interplay between iron homeostasis and fungal commensalism.
Chemo- and optogenetic activation of hypothalamic Foxb1-expressing neurons and their terminal endings in the rostral-dorsolateral PAG leads to tachypnea, bradycardia, and immobility
Authors: Cola Reto B , Roccaro-Waldmeyer Diana M , Naim Samara , Babalian Alexandre , Seebeck Petra , Alvarez-Bolado Gonzalo , Celio Marco R
Published: May 2023

Foxb1 -expressing neurons occur in the dorsal premammillary nucleus (PMd) and further rostrally in the parvafox nucleus, a longitudinal cluster of neurons in the lateral hypothalamus of rodents. The descending projection of these Foxb1+ neurons end in the dorsolateral part of the periaqueductal gray (dlPAG). The functional role of the Foxb1+ neuronal subpopulation in the PMd and the parvafox nucleus remains elusive. In this study, the activity of the Foxb1+ neurons and of their terminal endings in the dlPAG in mice was selectively altered by employing chemo- and optogenetic tools. Our results show that in whole-body barometric plethysmography, hM3Dq-mediated, global Foxb1+ neuron excitation activates respiration. Time-resolved optogenetic gain-of-function manipulation of the terminal endings of Foxb1+ neurons in the rostral third of the dlPAG leads to abrupt immobility and bradycardia. Chemogenetic activation of Foxb1+ cell bodies and ChR2-mediated excitation of their axonal endings in the dlPAG led to a phenotypical presentation congruent with a ‘freezing-like’ situation during innate defensive behavior.
Design of wireless battery management system monitoring and automated alarm system based on improved long short-term memory neural network
Authors: Zhang Qingyu
Published: May 2023

The battery management system (BMS) can intelligently manage and maintain each battery unit while monitoring its status, thereby preventing any possible overcharge or over-discharge of the battery. In BMS research, battery state parameter collection and analysis are essential. However, traditional data collection methods require personnel to be present at the scene, leading to offline data acquisition. Therefore, this study aimed to develop a wireless BMS monitoring and alarm system based on socket connection that would enable researchers to observe the operating parameters and problem details of the battery pack from a distance. A device like this effectively raises the battery’s level of cognitive control. In the study, the researchers first designed the overall scheme of the BMS remote monitoring system, followed by building a wireless BMS monitoring and alarm system. Performance evaluations of the system were then conducted to confirm its effectiveness. A Long Short-Term Memory (LSTM) network enhanced by the Batch Normalization (BN) technique was applied to the time series data of battery parameters to solve the large accuracy inaccuracy in battery state of charge estimate. Furthermore, the Denoise Auto Encoder (DAE) algorithm was utilized to denoise the data and reduce the model’s parameter dependence. The accuracy and robustness of the estimation are improved, and the model error is gradually stabilized within 5%.
Identification and Characterisation of Salmonella spp. Isolated from Stool Samples of a Food Poisoning Outbreak in Chite, Mizoram, India due to Consumption of Bekang-Um (Fermented Soybean)
Authors: Vangchhia Belinda L , Hnamte Sairengpuii , Koch Nirensingh , . Lalthlengliani , Dutta Tapan Kumar
Published: May 2023

Introduction: Traditional fermented soybean (“bekang-um”) is widely consumed by the indigenous Mizo tribe in Mizoram and plays a significant part of the local staple food. They are commonly prepared with herbs like culantro and often with just locally dried chilli flakes, implying it is mostly consumed raw without further cooking. Though it plays a staple part of the diet because of its unique taste, awareness on proper and regulated hygienic conditions during its preparation and fermentation processes is quite negligent. The fermentation process often warrants for the growth of not only commensal lactic acid fermenter bacteria like Acinetobacter spp., Lactobacillus spp., but also provides ample growth conditions for harmful bacteria like Salmonella spp., Clostridium spp., Intestinal Pathogenic E.Coli (IPEC) and Bacillus cereus. Aim: Phenotypic and molecular characterisation of Salmonella spp. isolated from the fermented food product bekang-um. Materials and Methods: The cross-sectional study was conducted within three months (October to December, 2020) in Multidisciplinary Research Unit (MRU), Zoram Medical College in collaboration with the Department of Veterinary Microbiology, CVSc and AH, Central Agricultural University, Selesih, Mizoram. A total of 18 stool samples were collected from patients (living in Chite, a small locality in Aizawl) who were still exhibiting symptoms of food poisoning (diarrhoea, vomiting and nausea) after consumption of fermented soybean all bought from their local neighbourhood fermenter and seller of the food item. The data was tabulated and statistically analysed using Microsoft Excel and sensitivity/resistance patterns were expressed in percentages. Results: Salmonella spp. was isolated from 17 out of 18 stool samples collected. Out of 17 samples, 15 exhibited Multi-Drug Resistance (MDR) phenotypically to clinically relevant and widely used antibiotics like cefotaxime, ceftriaxone, ciprofloxacin, amoxicillin-clavulanic acid. Alarmingly, resistance genes like blaCTX-M1 (70.6%), blaCTX-M2 (35.3%), blaSHV (70.6%), blaTEM (52.9%), blaNDM (5.8%), blaAmpC (100%), blaKPC (29.4%), blaVIM (23.5%), blaIMP (11.8%) were commonly detected. Moreover, Salmonella virulence determinants like invA (41.2%), stn (41.2%), and biofilm-associated virulence genes like csgA (11.8%), csgD (70.6%) and adrA (5.9%) were also identified. Conclusion: The identification and characterisation of Salmonella spp. isolated from a widely consumed food product “bekangum” (fermented soybean) with co-occurring crucial virulence, biofilm-producing and resistance gene determinants is quite alarming. The findings suggest the urgent need of implementing food safety conditions and proper preparation standards of the exotic food item, and the seriousness of the potential threat it can cause in cases of unhygienic fermentation processes.
Distribution of Different Types of Cystic Breast Lesions and their Imaging Features: A Retrospective Observational Study
Authors: Singh Neha , Agrawal Prasant , Singh Deepak Kumar , Mandvee Ojha Mandvee Ojha
Published: May 2023

Introduction: Cystic disease of the breast is very common and present in women aged 35-50 years. They can be detected incidentally or present with lump, pain, or discharge. Confusion occurs in the appropriate classification and management of such cystic lesions. These lesions characteristically appear as circumscribed masses on mammography, but can be properly evaluated on ultrasound. Although the variable imaging features sometimes necessitate biopsy for confirmation of the diagnosis. Aim: To estimate the prevalence of different types of cystic breast lesions and to study the imaging spectrum and features of cystic breast lesions. Materials and Methods: This descriptive observational retrospective study was undertaken on all the women who presented for screening or diagnostic mammography and had ultrasonographically detected cystic component in the breast lesions. Based on the mammography and ultrasonographic features, cystic lesions were classified and final Breast Imaging Reporting and Data System (BI-RADS) category was assigned. Fine Needle Aspiration Cytology (FNAC) or biopsy was performed whenever required. The values were represented in number and percentage. Results: Out of 836 women who had undergone mammography and Ultrasonography (USG), 134 patients were diagnosed with cystic breast lesions. Simple cyst with or without fine septa was most common type of cystic lesion present in 53 (39.6%) cases. It was followed by complex solid cystic lesion seen in 36 (26.8%) cases, complicated cyst 30 (22.4%) and complex cyst with thickened wall or septa in 15 (11.2%) cases. Conclusion: Cystic breast lesions are common entities with variable and overlapping imaging characteristics, based on which they can be categorised as BI-RADS 2 to BI-RADS 5 lesions.
Assessment of Abdominal Aorta Diameter on Contrast-enhanced Computed Tomography: A MDCT-based Observational Study
Authors: Naik Rakhee Shashikant , Raghuraj U
Published: May 2023

Introduction: Average size of the abdominal aorta is less than 3 cm which variates with time. The increase in abdominal aortic dimensions more than 3 cm can result in the presence of ectasia which can further convert into an aneurysm. The expansion rate can also lead to aortic dissection and rupture. Its increasing dimensions can influence to give rise to numerous other abdominal aortic conditions and be fatal due to the aortic wall stress. Monitoring the variation in the abdominal aorta is now possible with the various advancements in imaging techniques including Computed Tomography (CT). Aim: To measure the Anteroposterior (AP) and Right-Left (RL) diameters of the abdominal aorta on Contrast-enhanced Computed Tomography (CECT) abdomen and to analyse its variation with age and gender. Materials and Methods: A cross-sectional observational study was conducted in the Department of Radiodiagnosis at KS Hegde Charitable Hospital, Deralakatte, Mangaluru, Karnataka, India. The duration of the study was 11 months, from April 2020 to March 2021. A total of 81 patients referred for CECT abdomen divided into two age groups of 20-40 years and 41- 80 years. The scan was performed using 16-slice Multidetector Computed Tomography (MDCT). On the reconstructed axial images, the abdominal aortic diameters were measured at the level of T12-L1. The non parametric Mann-Whitney U test was used to compare the RL and AP diameters with respect to age groups. Unpaired t-test was used to compare the RL and AP diameters with respect to gender. Paired t-test was used to compare AP diameter on contrast and non contrast scans. Results: The mean age of study participants was 47±14.83 years and were divided into two age groups between 20-40 years and 41-80 years. Out of the 81 cases, 31 (38%) were in the age group of 20-40 and 50 (62%) were in the age group of 41-80 years. There was a significant increase in the AP and RL abdominal aortic diameter with age (p-value <0.001) and also males were found to have significantly higher abdominal aorta diameter than females (p-value <0.001) in both the age groups of 20-40 and 41-80 years. Also, the abdominal aorta diameter measurements on Non Contrast Computed Tomography (NCCT) and CECT abdomen showed no notable difference. Conclusion: The present study concluded that, there was a remarkable variation in the diameter of the abdominal aorta with age and gender. Besides, the abdominal aorta diameter measurements on NCCT and CECT abdomen showed no notable difference.
Attention Deficit Hyperactivity Disorder and Use of Mobile Phones among Children- Need for Concern?
Authors: Varghese Aby Dany , Mathew Geethu , Xson Cinderella
Published: May 2023

Introduction: The prevalence of Attention Deficit Hyperactivity Disorder (ADHD) is on the rise. Among multiple factors that are linked with ADHD, electronic media use has been gaining considerable attention recently. There is only a limited source of information regarding the burden of ADHD and its association with screen time in the Indian context. Aim: Screening of the children for ADHD and its association with mobile phone use at an outpatient service in a tertiary care hospital in Kerala. Materials and Methods: A cross-sectional questionnaire-based study was conducted among 157 children in the outpatient services in a tertiary care hospital in Pathanamthitta district, Kerala, India. School-going children aged between 6 and 11 years were included in the study. ADHD screening was done using Conner’s Abbreviated Rating Scale (CARS). Results: The mean age of children was 8.1±1.9 years. All the participants used mobile phones, and 15 (9.6%) owned one. The mean duration of mobile phone use per day was 1.4±0.7 hours. Among participants, 53 (33.8%) used mobile phones for more than one hour daily. Parents reported that nearly one-fifth of the children use mobile phones late at night (after 10 pm). Among children, 22.9% screened positive for ADHD. The ADHD scores are significantly correlated with the duration of mobile phone use (r=0.368 p<0.001). Among the children who used mobile phones for more than a year, 32.1% screened positive for ADHD (OR=3.21, CI 1.41-7.32). The mean ADHD score was significantly higher among children with >1 hour of mobile phone use/day than those who use <1 hour/day (t-test=-2.27 p-value=0.025). The vast majority, 148 (94.2%), also noticed behavioural changes among children when denied mobile phones. Significant changes included anger (22.9%), sadness (31.8%), withdrawal (20%), frustration (17.8%) and violence (8.9%). Conclusion: In this study, 22.9% of children screened positive for ADHD. Mobile phone use was found to be significantly associated with ADHD.
Assessment of Social Functioning among Adolescent School-going Children in Hooghly District, West Bengal, India: A Cross-sectional Study
Authors: Das Sulagna , Gupta Sukanya , Banerjee Sumitaksha , Das Mridul , Neogi Riddhiman , Mukherjee Soumopriyo
Published: May 2023

Introduction: Adolescents form a socially significant segment of the population. The analysis of social functioning, a sensitive indicator of underlying mental ailments, amongst them is a good measure to find out their mental health status. Aim: To assess the social functioning skills and its associated factors among adolescent school-going children in Hooghly District, West Bengal, India. Materials and Methods: A descriptive, cross-sectional questionnaire-based was conducted among 1056 (mean {SD) age=15.53±1.3 years} school-going adolescent children in four randomly selected English medium private co-educational schools, from Class IX to XII, in Hooghly District, West Bengal, India, for a period of two months from June 2022-July 2022. The Child and Adolescent Social and Adaptive Functioning Scale (CASAFS), a validated tool consisting of 24 items designed to measure psychosocial functioning, was used. A Likert scale scoring was done for each item. Adolescents scoring below the 75th percentile of the total score were classified as “poor social adaptive functioning skill” and those above 75th percentile as “good social adaptive functioning skill”. The data was analysed using IBM Statistical Package for the Social Sciences (SPSS), version 23.0 software. Descriptive statistics like mean, median, percentile, standard deviation were generated. Analytical statistics like chi-square test was applied to find out the relationship between categorical variables i.e., social functional skill and socio-demographic profile and a p-value of <0.05 was considered as significant. Result: Out of 1056 students included in the study. There were 318 (30.1%) Class IX students, 229 (21.7%) Class X students, 204 (19.3%) Class XI students and 305 (28.9%) Class XII students. The age of the students ranged from 13 to 18 years. 219 (20.7%) had the good social functioning skill and 837 (79.3%) had poor social functioning skill. The mean (SD) score of all the domains combined was 70.5 (8.05), with ‘Family Relationship domain’ having highest mean (SD) score 19.5±3.0 and ‘Peer relationship domain’ having the least mean (SD) score 15.9±3.1. ‘Good social functioning skills’ was significantly associated with those belonging to the age group of 17-18 years, having increased number of siblings (p=0.001) higher mother’s educational status (p=0.003). Conclusion: From the present study, it was observed that a very meagre number of students possessed good social functional ability. Improvement of social functioning skills indirectly helps in improving mental health and adolescents are the corner stones to initiate this process.
Posture Correction Interventions to Manage Neck Pain among Computer and Smartphone Users- A Narrative Review
Authors: Khanum Fatima , Khan Abdur Raheem , Khan Ashfaque , Ahmad Ausaf , Ahmed Hashim
Published: May 2023

Digital technology has affected practically every aspect of modern life. Sitting is something that humans do for a number of purposes, including work (particularly for those who work in the computer industry), and for enjoyment. Daily computer use causes frequent neck and back pain. Flexed head and neck postures might cause neck pain during work. Pauses and postural modifications help avoid pain and sickness. Recent wearables can sense spinal alignment and provide immediate feedback on improper posture. Posture monitoring can help treat or change a user’s posture. In this narrative review, Google Scholar, PubMed, Cross-Ref, Cochrane, and ResearchGate were searched for English-only papers using review-specific keywords and fifty-one items were found. The search was narrowed by using more particular terms, such as “wearable postural correction sensors,” “forward head posture,” “neck discomfort in smartphone or computer users,” and “neck workouts.” Only current papers from 2015 onwards were considered. After filtering for relevancy, twenty-five articles were included. Researcher should identify intervention functions, policy categories, and tactics for behaviour change. Researchers have also examined neck discomfort, forward head posture in young individuals while using smartphones and computers, and posture correction using a wearable postural correction sensor. And also appropriate arrangement and support to administering a home and workplace fitness programme that eliminates pain and impairment while enhancing Forward Head Posture (FHP) and endurance. This review aimed to thoroughly examine existing literature for evidence concerning prevalent problems among smartphone and computer users such as neck discomfort and forward head position, postural correction sensor, and impact of exercises on neck discomfort.