bluuebunny/crossref_metadata_2025 huggingface dataset:
Association Between Thyroid Diseases and Parkinson’s Disease: A Nested Case-Control Study Using a National Health Screening Cohort
Authors: Kim Ji Hee , Lee Heui Seung , Ahn Jun Hyong , Oh Jae Keun , Chang In Bok , Song Joon Ho , Wee Jee Hye , Min Chan Yang , Yoo Dae Myoung , Choi Hyo Geun
Published: October 2020

Background: Although the dopaminergic system is interconnected with the hypothalamic-pituitary-thyroid axis, few studies have explained the causal relationship between thyroid disease and Parkinson’s disease (PD). Objective: The goal of this study was to investigate the association between thyroid diseases and PD in Korean residents. Methods: The Korean National Health Insurance Service-National Sample Cohort, which includes individuals aged ≥40 years, was assessed from 2002 to 2015. A total of 5,586 PD patients were matched by age, sex, income, and the region of residence with 22,344 control participants at a ratio of 1:4. In the PD and control groups, previous histories of levothyroxine treatment, goiter, hypothyroidism, thyroiditis, and hyperthyroidism were investigated. Results: The rates of levothyroxine treatment for more than 3 months, hypothyroidism, and hyperthyroidism were higher in the PD group than the control group (3.2%, 3.8%, and 2.8% vs. 2.5%, 2.9%, and 1.9%, respectively, p < 0.05). The adjusted odds ratios (ORs) in model 2, which was adjusted for all potential confounders, for hypothyroidism and hyperthyroidism in the PD group were 1.25 (95% confidence interval (CI) 1.01–1.55, p = 0.044) and 1.37 (95% CI 1.13–1.67, p = 0.002), respectively. In subgroup analyses, the association between hypothyroidism and PD was maintained in men older than 70 years and the association between hyperthyroidism and PD was maintained in women younger than 70 years. Conclusion: Both hyperthyroidism and hypothyroidism were associated with higher risk of PD, particularly for women younger than 70 years and men older than 70 years, respectively.
Diet Quality and Risk of Parkinson’s Disease: A Prospective Study and Meta-Analysis
Authors: Liu Yi-Hsuan , Jensen Gordon L. , Na Muzi , Mitchell Diane C. , Wood G. Craig , Still Christopher D. , Gao Xiang
Published: October 2020

Background: Several dietary components have been shown to be neuroprotective against risk of neurodegeneration. However, limited observational studies have examined the role of overall diet quality on risk of Parkinson’s disease. Objectives: We examined the associations between diet quality and risk of Parkinson’s disease in a prospective cohort study and meta-analysis. Methods: Included in the cohort study were 3,653 participants (1,519 men and 2,134 women; mean age: 81.5 years) in the Geisinger Rural Aging Study longitudinal cohort in Pennsylvania. Diet quality was assessed using a validated dietary screening tool containing 25 food- and behavior-specific questions in 2009. Potential Parkinson’s cases were identified using electronic health records based on ICD9 (332.*), ICD10 (G20), and Parkinson-related treatments. Hazard ratios (HRs) and 95% confidence intervals (CIs) across diet quality tertiles were calculated using Cox proportional hazards models after adjusting for potential confounders. We further performed a meta-analysis by pooling our study with four published papers on this topic. Random-effects model was utilized to calculate the pooled risk ratios and 95% CIs. Results: During a mean of 6.94 years of follow-up, 47 incident Parkinson’s cases were documented. Having high diet quality at baseline was associated with lower Parkinson’s disease risk (adjusted HR for the highest vs the lowest diet quality tertile = 0.39; 95% CI: 0.17, 0.89; p-trend = 0.02). The meta-analysis including 140,617 individuals also showed that adherence to high diet quality or a healthy dietary pattern was associated with lower risk of Parkinson’s disease (pooled risk ratio = 0.64; 95% CI: 0.49, 0.83). Conclusion: Having high diet quality or a healthy dietary pattern was associated with lower future risk of Parkinson’s disease.
How children and their parents value using the Canadian Occupational Performance Measure (COPM) with children themselves
Authors: Verkerk Gijs J.Q. , van der Molen-Meulmeester Lisanne , Alsem Mattijs W.
Published: October 2020

PURPOSE: Although the Canadian Occupational Performance Measure (COPM) is used with children, it is unclear how they and their parents experience this. This study aims to investigate the opinions of children and their parents about the COPM when it is used with children. METHODS: Semi-structured interviews were performed with 23 children varying in age between 8 and 18 years. The transcripts of the interviews were analysed using MAXQDA software to discover overarching themes. Parents’ responses to an eight-item multiple-choice questionnaire were analysed using SPSS software. RESULTS: Five themes extracted from the interviews with the children show: My way of doing the COPM; The COPM shows my own problems and wishes for change; The COPM is important for identifying the support I need; The influence of my parents and my therapist; and The COPM is suitable for me. The children experienced the COPM as a valuable tool for determining and measuring the impact of an intervention. The parents experienced the COPM as suitable for their child and judged that the child’s scores were useful for showing the outcome of an intervention. CONCLUSION: Both the children and their parents valued the COPM as an outcome measure for intervention.
Use and abuse of official statistics in Latin America: The case of Argentina
Authors: Beker Victor A.
Published: October 2020

In line with the Fundamental Principals of Official Statistics to produce valid and reliable statistics Governments need to provide the legal framework and resources to the statistical system to allow statisticians to produce the required statistics, without interference, using the best available methodology and techniques from the most suited sources of information. In Latin America and the Caribbean the colonial past affected and still affects the production of statistics. During the Colonial period statistics were of limited scope and use, mostly serving the interests of the Colonial powers. After independence in Latin America statistics became an instrument for development only after World War II, while in the Caribbean the newly independent nations had to adjust the Colonial system to national souvereignity. Conflicts between statistical independence and administrative desire and convenience did occur. Occasionally statisticians were under pressure to modify results to serve administrative or political purposes. An extreme case of Government interference with statistical activities is the case of Argentine since 2007. The gross manipulation of the Consumer Price Index (CPI) that began at that time was aimed at concealing the rise in inflation which took place at the beginning of that year. Statisticians in the National Statistical Office who refused to be part of the forgery were demoted, and dismissed while others resigned. The alteration of the CPI severely affected other statistical indices. Private consultants and researchers were subject to criminal prosecutions and punished with hefty fines for the “crime” of publishing their own price estimates. Although in most cases the judicial system acquitted them, this happened some years later, and currently there are still researchers awaiting the final judgement. In spite of the reaction by public opinion and the world statistical community nothing changed substantially until now. The paper concludes with some recommendations to safeguard the integrity of statistics inspired by this sad experience.
A survey on knowledge graph embeddings with literals: Which model links better literal-ly?
Authors: Gesese Genet Asefa , Biswas Russa , Alam Mehwish , Sack Harald
Published: October 2020

Knowledge Graphs (KGs) are composed of structured information about a particular domain in the form of entities and relations. In addition to the structured information KGs help in facilitating interconnectivity and interoperability between different resources represented in the Linked Data Cloud. KGs have been used in a variety of applications such as entity linking, question answering, recommender systems, etc. However, KG applications suffer from high computational and storage costs. Hence, there arises the necessity for a representation able to map the high dimensional KGs into low dimensional spaces, i.e., embedding space, preserving structural as well as relational information. This paper conducts a survey of KG embedding models which not only consider the structured information contained in the form of entities and relations in a KG but also its unstructured information represented as literals such as text, numerical values, images, etc. Along with a theoretical analysis and comparison of the methods proposed so far for generating KG embeddings with literals, an empirical evaluation of the different methods under identical settings has been performed for the general task of link prediction.
SINTESIS DAN KARAKTERISASI NANOPARTIKEL EMAS MENGGUNAKAN BIOREDUKTOR DARI EKSTRAK DAUN BERENUK
Authors: Amin Fauzan , Mahardika Micha , Fatimah Siti
Published: October 2020

Perkembangan teknologi industri di segala sektor semakin menuntut lahirnya perangkat-perangkat yang lebih sederhana, berukuran kecil, dengan bahan murah, tetapi memiliki kemampuan yang sama atau lebih canggih daripada perangkat-perangkat sebelumnya. Tuntutan ini dapat dijawab dengan adanya nanoteknologi. Nanopartikel emas (AuNPs) merupakan bagian dari nanoteknologi yang semakin luas manfaatnya  dalam kehidupan manusia antara lain di bidang lingkungan, biomedis, tekstil, industri elektronika serta energi . Sintesis Au-NPs diawali dengan mereduksi ion Au(III) mengunakan reduktor dari tumbuhan karena lebih aman dan ramah lingkungan dibandingkan dengan bahan anorganik lainnya. Salah satu tumbuhan yang potensial digunakan sebagai bioreduktor adalah daun berenuk (Crescentia cujete Linn) yang melimpah keberadaanya tapi belum banyak dimanfaatkan oleh manusia. Penelitian ini bertujuan menentukan pengaruh volume bioreduktor terhadap pembentukan AuNPs secara statistik dan ukuran AuNPs menggunakan TEM. Hasil penelitian menunjukkan bahwa pada volume bioreduktor  tidak berpengaruh terhadap pembentukan AuNPs setelah diolah menggunakan SPSS, mempunyai ukuran rata-rata 11,249 nm dengan bentuk morfologi anisotropik.
KONSENTRASI MERKURI (Hg) PADA AIR SUNGAI DAN SEDIMEN SUNGAI DESA TAMBANG SAWAH AKIBAT PENAMBANGAN EMAS TANPA IZIN (PETI)
Authors: Mulyadi Irwan
Published: October 2020

Maraknya aktivitas Penambangan Emas Tanpa Izin (PETI) yang merupakan penambangan rakyat peninggalan kolonial Belanda yang terletak di Desa Tambang Sawah, Kecamatan Pinang Belapis, Kabupaten Lebong menimbulkan permasalahan lingkungan khususnya merkuri pada perairan sungai tersebut. Sampel air dan sedimen diambil dari lima titik yang terletak sepanjang hulu hingga batas desa. Konsentrasi total merkuri pada air mulai dari hulu sampai hilir sungai batas desa berturut-turut yaitu <0,0003 ppm, 0,0004 ppm, 0,0007 ppm, 0,0008 ppm dan 0,0011 ppm dan konsentrasi total merkuri pada sedimen dari hulu sampai hilir sungai batas desa berturut-turut yaitu 1,34 ppm, 4,18 ppm, 35,89 ppm, 50,32 ppm dan 114,37 ppm dimana kondisi ini melebihi ambang batas yang ditentukan . Peningkatan konsentrasi merkuri dari hulu sampai hilir sungai  ini dikarenakan terjadinya akumulasi kegiatan pertambangan emas rakyat yang menggunakan merkuri dan melepas limbahnya ke sungai
A konspiráció szempontjainak megjelenése az állambiztonság kapcsolati forrásból származó információgyűjtésének területein
Authors: Dobák Imre , Mezei József , Regényi Kund
Published: October 2020

A tanulmány a hazai állambiztonsági főcsoportfőnökségi rendszer működésének időszakára visszatekintve, a humán kapcsolati forrásból származó információgyűjtés területét érintően a konspiráció gondolatkörét és annak szabályzatokban történő megjelenését vizsgálja. Az állambiztonsági szervek titkos működésének részletesebb megismerése 1990 után vált lehetővé, többek között a tevékenységet szabályozó normák nyilvánossá válásával. A rendszerre jellemző „konspiráció” követelménye az írott szabályozókon keresztül az évtizedek alatt beépült a mindennapi munkavégzésbe.
Szervezetvezetési módszerek – azaz hogyan váljunk sikeres vezetővé
Authors: Kovács Gábor
Published: October 2020

A szervezetek vezetése rendkívül összetett és bonyolult folyamat, amelynek megvannak a jól bevált módszerei. A vezetés tanulható, de ahhoz, hogy valaki sikeres vezetővé váljon, megfelelő szintű általános műveltség, szakterületi tudás és szakmai ismeretkör birtoklása, az adott szakterületen eltöltött gyakorlat és végezetül, általános vezetéselméleti felkészültség szükséges. A tanulmány a témához kapcsolódó elméleti ismereteken túl hasznos gyakorlati útmutatást ad a kezdő és gyakorló vezetők számára ahhoz, hogy az általuk vezetett szervezet sikeres legyen, ezáltal ők maguk sikeres vezetővé váljanak.
Entwicklung einer mobilen Anwendung für sichere Chirurgie Checkliste
Authors: Silva Rafael Henrique , Gatti Marcia Aparecida Nuevo , Marta Sara Nader , Caram Nirave Reigota , Franzolin Solange de Oliveira Braga , Pedro Ketilin Mayra , Lopes Jaqueline de Souza
Published: October 2020

Kommunikations- und Informationstechnologien beeinflussen zunehmend die Gesundheitsmaßnahmen sowie die Patientensicherheit. Ziel dieser Arbeit war es daher, eine Anwendung zur Überprüfung und Kontrolle aller Phasen der von der Weltgesundheitsorganisation vorgeschlagenen Checkliste für sichere Chirurgie zu entwickeln, um die Sicherheit von Patienten zu verbessern, die sich einer Operation unterziehen. Das Forschungsproblem liegt gerade im Fehlen von Anwendungen für mobile Geräte, die das Sicherheitsbedürfnis des Patienten erfüllen können. Dies ist eine Studie zur technologischen Entwicklung einer Anwendung mit der Möglichkeit, in jedem Gesundheitsdienst eingesetzt und einfach auf Mobilgeräten installiert zu werden. Die Anwendung wurde auf der Grundlage der von der Weltgesundheitsorganisation erstellten Checkliste für sichere Chirurgie erstellt. Die Anwendung ermöglicht die Identifizierung des Patienten anhand von drei Kennungen. Anschließend werden alle Punkte in den drei Phasen der Checkliste für sichere Operationen berücksichtigt: Vor der Einleitung des Anästhetikums, vor dem chirurgischen Einschnitt und bevor der Patient den Raum verlässt. Am Ende aller Phasen der Anwendung wird das Risiko für die Patientensicherheit berechnet. Die entwickelte Anwendung ist ein Tool, das in Gesundheitseinrichtungen implementiert und von Fachleuten verwendet werden kann, die im Operationssaal arbeiten.
Разработка мобильного приложения для безопасного хирургического вмешательства
Authors: Silva Rafael Henrique , Gatti Marcia Aparecida Nuevo , Marta Sara Nader , Caram Nirave Reigota , Franzolin Solange de Oliveira Braga , Pedro Ketilin Mayra , Lopes Jaqueline de Souza
Published: October 2020

Коммуникационные и информационные технологии все чаще влияют на действия в области здравоохранения, а также на безопасность пациентов. Таким образом, это исследование было направлено на разработку заявки на конференцию и контроль всех этапов контрольного перечня безопасной хирургии, предложенного Всемирной организацией здравоохранения для повышения безопасности пациентов, представленных на операцию. Проблема исследований заключается именно в отсутствии мобильных приложений, способных обеспечить безопасность пациентов. Это исследование применяется в технологическом развитии приложения с возможностью развертывания в любой медицинской службе и легкой установки на мобильные устройства. Приложение было построено на основе контрольного перечня безопасной хирургии, установленного Всемирной организацией здравоохранения. Приложение позволяет идентифицировать пациента через три идентификатора. Позже он рассматривает все элементы трех этапов контрольного перечня безопасной хирургии: Перед анестезией индукции, перед хирургическим разрезом и до того, как пациент покидает комнату. В конце всех этапов применения, он рассчитывает риск для безопасности пациентов. Разработанное приложение является инструментом, который может быть реализован в медицинских учреждениях и использоваться профессионалами, работающими в операционной.
Desarrollo de la aplicación móvil para la lista de verificación de cirugía segura
Authors: Silva Rafael Henrique , Gatti Marcia Aparecida Nuevo , Marta Sara Nader , Caram Nirave Reigota , Franzolin Solange de Oliveira Braga , Pedro Ketilin Mayra , Lopes Jaqueline de Souza
Published: October 2020

Las tecnologías de la comunicación y la información están influyendo cada vez más en las acciones sanitarias, así como en la seguridad de los pacientes. Por lo tanto, este estudio tenía como objetivo desarrollar una solicitud para la conferencia y el control de todas las etapas de la lista de verificación de Cirugía Segura sugerida por la Organización Mundial de la Salud mejorando la seguridad de los pacientes sometidos a cirugía. El problema de la investigación radica precisamente en la ausencia de aplicaciones móviles capaces de satisfacer la necesidad de seguridad del paciente. Este estudio se aplica en el desarrollo tecnológico de una aplicación con posibilidad de implantación en cualquier servicio de salud y fácil instalación en dispositivos móviles. La aplicación fue construida sobre la base de la lista de verificación de cirugía segura establecida por la Organización Mundial de la Salud. La aplicación permite la identificación del paciente a través de tres identificadores. Más tarde contempla todos los elementos de las tres etapas de la lista de verificación de la cirugía segura: Antes de la inducción anestésica, antes de la Incisión Quirúrgica y Antes de que el Paciente salga de la Habitación. Al final de todos los pasos de la aplicación, calcula el riesgo para la seguridad del paciente. La aplicación desarrollada es una herramienta que puede ser implementada en instituciones de salud y utilizada por profesionales que trabajan en el quirófano.
An Econometric Analysis on Remittance and Economic Growth in Bangladesh
Authors: Shafiul Islam Md
Published: October 2020

In Bangladesh, migrant worker’s remittances constitute one of the most significant sources of external finance. This paper investigates the existence of relation between remittance inflow and GDP and the causal link between them in Bangladesh by employing the Granger causality test under a VECM framework. Using time series data over a 38 year period, we found that growth in remittances does lead to economic growth in Bangladesh. In addition to the relationship, this paper also points out some issues that are working as impediments in getting remittance and give some recommendations to overcome those impediments.
А.А. Смирнов и вопросы психотехники
Authors: Стоюхина Н.Ю.
Published: October 2020

В статье речь идет об А.А. Смирнове – советском психологе, ученом и организаторе науки. Среди множества его научных интересов психотехнические исследования в 1920-1930-е годы занимали особое место. Его книга «Психология профессий», посвященная профессиональному отбору, не затерялась на фоне книг его коллег по этой теме. Интерес к вопросам психологии труда сохранялся у А.А. Смирнова на протяжении всего его научного пути.
HALAC n. 10 Edição Suplementar 2 (2020)
Authors: SOLCHA HALAC
Published: October 2020

HALAC n. 10 Edição Suplementar 2 (2020)
Brexit and Its Impact on Poland’s Policy Towards Europe – An Attempt to Forecast
Authors: Chojan Adrian
Published: October 2020

Brexit has betrayed the disadvantages of the European project along with the fact that European institutions have no desire to conduct deeper reforms. Brexit cannot be considered without the stance that the British have developed not only in the last few years but generally over the period of its integration with continental Europe. A study shows the political consequences of the UK’s exit from the European Union alog with the potential scenarios of Poland’s European policy in the next 2–3 years. This article presents three scenarios for the development of Poland's European policy, i.e. the British scenario, a conservative scenario and a pro-European scenario. In addition, this article aims to show the potential activities of the Polish government in the context of selected scenarios for the development of the situation in Europe. Currently, the most likely is the British scenario, where the Polish government concentrates on those areas of integration that are important to it. The European Union will be treated by Poland as an economic organization providing access to the common European market as well as political support in the event of disputes with the powers. The adoption of the British scenario by Poland assumes an evolutionary drift towards polexit. The least realistic choice of scenario is the strongly pro-European approach. This would require a total change in Poland's European policy strategy and the abandoning of internal reforms.
Sweden and the Migration Crisis: Political and Security Aspects
Authors: Gruszczak Artur
Published: October 2020

This article aims to make an insight into the conditions of immigration policy and actions undertaken by the Swedish authorities and political parties in the face of the migration crisis in Europe after 2015. A hypothesis presented here assumes that a decisive evolution of the attitudes of the Swedish authorities, political parties, and society towards a restrictive approach to immigration arose from the awareness of the negative consequences of migration management for the Swedish socio-economic model and the political scene. The theoretical framework used in this article is the concept of policy responsiveness, including the ability of political authorities to respond effectively and lawfully to the needs and expectations of the citizens. Process tracing was applied as a research method useful for following the transformation process of Sweden’s immigration policy. Statistical data, documents issued by the government and political parties, as well as the subject literature were the sources utilised in the research. Conclusions drawn from the research point to the tightening of immigration policy as a result of the fear of a prolonged pull effect on foreigners and concern surrounding the appropriate handling of immigration in full accordance with the adopted model of immigration policy.
Preliminary Study of Adaptation of the Motivation Model for the Perry Public Service (1996) within the Portuguese Context
Authors:   Center for Public Administration and Public Policies, Higher Institute of Social and Political Science, University of Lisbon, Portugal, Fonseca João , Nascimento José ,   Center for Public Administration and Public Policies, Higher Institute of Social and Political Science, University of Lisbon, Portugal, Dias Damasceno ,   Center for Public Administration and Public Policies, Higher Institute of Social and Political Science, University of Lisbon, Portugal
Published: October 2020

Public Service Motivation (PSM) has been shown to be a consistent model in the various studies in which it was used. This study aims to contribute to the validation of PSM, conceptualized by Perry and Wise (1990), within the Portuguese context. Starting from the dimensions that make up PSM in the model proposed by Perry (1996), we intend to identify the dimensions with possible relevance to the Portuguese context. This research inserts itself into the context of a large project of validation of the PSM model representative of the Portuguese Public Administration. Using a questionnaire initially proposed by Perry (1996) which covers forty items to measure the six dimensions, we performed different Exploratory Factor Analyses (EFA) through the elimination of the items that presented a factor loading of below 0,50 and/or saturated with a factor loading greater than 0,50, in more than one extracted factor. Following this, by using the Confirmatory Factor Analysis (CFA), we compared the measurement model achieved (EFA) with the two other models. One was that initially proposed by Perry (1996) and the other was the final model discovered in this study by Perry (1996). The results obtained allowed the identification of three dimensions of the six proposed initially by Perry (1996) and two new dimensions which assume a reverse nature. They are Social Selfishness and Social Cynicism, there not being, however, any literature found to contextualize them within the scope of PSM. The implications of these results were also discussed and future studies suggested.
Estudo Preliminar de Adaptação do Modelo de Motivação para o Serviço Público de Perry (1996) para o Contexto Português
Authors:   Centro de Administração e Políticas Públicas, Instituto Superior de Ciências Sociais e Políticas, Universidade de Lisboa, Portugal, Fonseca João , Nascimento José ,   Centro de Administração e Políticas Públicas, Instituto Superior de Ciências Sociais e Políticas, Universidade de Lisboa, Portugal, Dias Damasceno ,   Centro de Administração e Políticas Públicas, Instituto Superior de Ciências Sociais e Políticas, Universidade de Lisboa, Portugal
Published: October 2020

A Motivação para o Serviço Público (PSM) tem revelado ser um constructo consistente nos diversos estudos em que tem sido utilizado. O presente estudo tem como objetivo contribuir para a validação para o contexto português do Modelo de Motivação para o Serviço Público (Public Service Motivations – PSM) conceptualizado por Perry e Wise (1990). Pretende-se, partindo das dimensões constituintes deste modelo identificar dimensões relevantes para o contexto público português. Insere-se, assim, no contexto de um projeto mais vasto de identificação e validação de um modelo da PSM representativo da Administração Pública Portuguesa. Partindo-se do questionário inicialmente proposto por Perry (1996), constituído por quarenta itens que medem as seis dimensões, foram realizadas diversas Análises Fatoriais Exploratórias (AFE) através da eliminação dos itens que apresentaram um factor loading inferior a 0,50 e/ou saturaram com factor loading superiores a 0,50 em mais do que um fator extraído. Em seguida, através de Análises Fatoriais Confirmatórias (AFC), o modelo resultante da AFE, foi comparado com outros dois modelos. Um foi o modelo inicial proposto por Perry (1996) e o outro foi o modelo final encontrado neste estudo (Perry, 1996). Os resultados obtidos permitiram identificar três dimensões das seis propostas inicialmente por Perry (1996) e duas novas dimensões que assumem uma natureza reverse. São elas o Egoísmo Social e o Cinismo Social, não tendo, no entanto, sido encontrada literatura que as contextualizassem no âmbito da PSM. Foram também discutidas as implicações destes resultados e sugeridos estudos futuros.
Antibacterial effect of Dimethyl sulfoxide extract of Aloe vera (Aloe barbadensis) leaf gel against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae
Authors: Haque Syed Didarul , Al Amin Abu Md Mayeenuddin , Islam Baishakhi , Nazneen Nazia , Karim Syeda Noorjahan , Rahman Md Abdur
Published: October 2020

An exploratory study based on laboratory experiment was carried out to determine the antibacterial effect of Dimethyl sulfoxide (DMSO) extract of Aloe vera leaf gel (DAE) against standard strains of Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae in the Department of Pharmacology & Therapeutics in collaboration with the Department of Microbiology, Mymensingh Medical College, Mymensingh, Bangladesh. DMSO extract was used in five different concentrations (100, 200, 300, 400 and 500 μg/ml). Dose dependent inhibitory effect was seen against the test organisms using disc diffusion method. Zone of inhibition (ZOI) were 8 mm, 13 mm, 15 mm, 16 mm and 21 mm against S. aureus; 0 mm, 8 mm, 13 mm, 15 mm and 18 mm against P. aeruginosa; 8 mm, 11 mm, 13 mm, 16 mm and 20 mm against E. coli; 0 mm, 9 mm, 12 mm, 14 mm and 18 mm against K. pneumoniae at 100, 200, 300, 400 and 500 μg/ml respectively. The minimum inhibitory concentration (MIC) was assessed by broth dilution technique. The MICs of DAE for S. aureus, P. aeruginosa, E. coli and K. pneumoniae were 300 μg/ml, 400 μg/ml, 400 μg/ml and 450 μg/ml respectively. From the study it was observed that DMSO extract of Aloe vera leaf gel possesses antibacterial effect against the test pathogens. The findings highlight the need for further extensive study to detect and isolate the biologically active ingredients present in the Aloe vera leaves which are responsible for antibacterial effect. Hopefully, that would lead to the discovery of new and more potent antimicrobial agents originated from Aloe vera.

Mediscope Vol. 7, No. 2: July 2020, Page 67-74
5. Sınıf Sosyal Bilgiler Dersinde Drama Yönteminin Kullanılmasına İlişkin Öğrenci Görüşleri
Authors: EZER Feyzullah , AKSÜT Selda
Published: October 2020

Araştırmanın amacı ortaokul beşinci sınıf Sosyal Bilgiler dersi “Bölgemizi Tanıyalım” ünitesinde yer alan konuların öğretiminde drama yönteminin nasıl kullanılabileceğine ilişkin drama etkinlikleri oluşturmak, oluşturulan drama etkinliklerinin öğrenciye etkisini araştırmak ve yöntem ile ilgili yapılan uygulamalara ilişkin öğrencilerin görüşlerini belirlemektir. Araştırma, nitel araştırma yaklaşımına uygun olan eylem araştırması ile yürütülmüştür. Araştırmanın çalışma grubunu 2013-2014 eğitim öğretim yılı Elazığ il merkezinde 5. sınıfta öğrenim gören 38 öğrenci oluşturmaktadır. Çalışma grubu amaçsal örnekleme yöntemlerinden biri olan kolay ulaşılabilir durum örnekleme ile belirlenmiştir. Araştırma verileri görüşme yöntemi ile yarı yapılandırılmış görüşme formu kullanılarak elde edilmiştir. Araştırmada elde edilen verilerin çözümlenmesinde içerik analizi yöntemi kullanılmış ve verilerin değerlendirilmesi için nitel veri analiz programından yararlanılmıştır. Araştırma sonucunda öğrencilerin drama yönteminde uygulamanın faydalarını konuyu öğrenme, özgüven, eğlenceli öğrenme ortamı, Sosyal Bilgiler dersine ilgi, birlik beraberlik ve kalıcı öğrenme şeklinde ifade ettikleri belirlenmiştir. Sosyal Bilgiler öğretmenlerin bu çağdaş öğretim yöntemini kullanmasının faydalı olacağı önerisinde bulunulabilir. Ayrıca bu yöntemin farklı derslerde, sınıf seviyelerinde kullanılması ve sınıf ortamlarının uygulamalara uygun olarak düzenlemesi önerilebilir.
Sosyal Bilgiler Öğretim Programı Ve 4-7. Sınıf Sosyal Bilgiler Ders Kitaplarının Coğrafya Kavramları Bağlamında Değerlendirilmesi
Authors: KAÇAR Turan , BULUT Birol
Published: October 2020

Bu çalışmanın amacı 2018 Sosyal Bilgiler Öğretim Programını (SBÖP) ve 2019-2020 eğitim-öğretim yılında Türkiye’de 4-7. sınıflarda okutulan sosyal bilgiler ders kitaplarını coğrafya kavramları bağlamında, çeşitli değişkenler açısından değerlendirmektir. Bu çalışma, nitel bir araştırma olup bu çalışmada nitel araştırmalarda uygulanan doküman analizi tekniği kullanılmıştır. Bu çalışmada, doküman olarak 2018 SBÖP ve Milli Eğitim Bakanlığının ülkemizde 2019-2020 eğitim-öğretim yılında okuttuğu 4-7. sınıf sosyal bilgiler ders kitapları incelenmiştir. Bu çalışma verilerinin analizinde betimsel analiz tekniği kullanılmıştır. Bu çalışmanın sonuçlarına göre; SBÖP’de yer alan 27 beceriden sadece dördü coğrafya kavramları ile doğrudan ilişkilidir. SBÖP’de yedi öğrenme alanı ve 131 kazanım vardır. SBÖP’de yer alan yedi öğrenme alanından sadece İnsanlar, Yerler ve Çevreler coğrafya kavramları ile bütünüyle ilgiliyken Üretim, Dağıtım ve Tüketim ve Küresel Bağlantılar öğrenme alanları ise kısmen coğrafya kavramları ile ilgilidir. SBÖP’de 4-7. sınıf düzeyindeki öğrenme alanlarında coğrafya kavramları bağlamında yer alan tüm kazanımların oranı %29,7 iken ders saati oranı ise %30,5’tir. 2019-2020 eğitim-öğretim yılında okutulan 4-7. sınıf sosyal bilgiler ders kitapları incelendiğinde sadece 7. sınıf sosyal bilgiler ders kitabındaki öğrenme alanlarında öğrenci öz değerlendirme formlarına yer verilmiştir. Bu sonuçlar doğrultusunda coğrafya kavramlarının sosyal bilgiler dersinde önemli bir oranda yer alması öğrencilerin bilişsel ve sosyal gelişimine katkı sağlayacağı söylenebilir.
Siber Zorbalık Bağlamında Twitter Fenomenleri
Authors: BÖLÜKBAŞ Kenan , KIRIK Ali Murat
Published: October 2020

Yakın geçmişte iletişimin temel mecrasının geleneksel medyadan yeni medya denilen sosyal medya alanına yönelmesiyle alışılagelmiş bazı kavramlar farklı anlamlara bürünmüştür. Bu kavramlardan biri de akran zorbalığıdır. Bu noktada teknolojinin “kötüye yorulması ve zarar verme amaçlı kullanılması” ile “siber (sanal) zorbalık” adı verilen yeni bir kavramı ortaya çıkmıştır. Siber zorbalık, sosyal medyada sıkça karşılaşılan bir olgudur. Yüksek takipçili hesaplara sahip olan Twitter fenomenleri de bazı takipçilerinin kendilerine ve diğer takipçilerine yönelttiği siber zorbalıkla mücadele etmek zorunda kalmaktadır. Twitter fenomenlerinin siber zorbalıkla ilgili deneyim ve düşüncelerini ortaya koymayı amaçlayan bu çalışma, fenomenolojik nitel bir araştırma olarak tasarlanmıştır. Yüksek takipçili beş Twitter fenomeninden konu bağlamında görüş alınarak, siber zorbalık olgusu Twitter fenomenlerinin deneyimleri ve bakış açıları ile ele alınmaya çalışılmıştır. Araştırma bulguları, diğer sosyal medya kullanıcıları gibi Twitter fenomenlerinin de çeşitli siber zorbalık davranışlarına maruz kaldıklarını, farklı boyut ve düzeylerde bu davranışlardan etkilendiklerini ve söz konusu davranışlarla baş etmek için çeşitli stratejiler geliştirdiklerini ortaya koymaktadır.
Branding “Keripik Singkong” Untuk Mewujudkan Desa Sejahtera Mandiri Berbasis Ekonomi Kreatif
Authors: Anggraheni Ika , Yuniar Ela , Tuanany Mohamad Saleh , Yusuf Ahsani Muhammad , Rachmawati Karina Safitri , Ibnul Qayyim Muhammad , Pradana Antoni Bagus , Dwi Narwani Anggi Ayu , Firdauzie Achmad Rafly , Hidayati Rizma Noer , Pratiwi Riska Dwi , Yusuf Laela Octaviana
Published: October 2020

Banyaknya potensi yang dimiliki oleh Desa Dadapan menjadikan semakin meningkat peluang perekonomian yang dimilikinya dan menjadikan deesa mandiri sejahtera berbasis ekonomi kreatif. Salah satunya dengan membuat industri kecil dalam rumah tangga untuk mengolah hasil pertanian yang dimilikinya dan memberikan kemasan yang menarik sehingga menarik perhatian konsumen dan berhasil memasarkan produk dengan lebih baik. Dengan jumlah penghasilan yang lebih baik setiap waktunya, menjadikan kami mahasiswa dari Kelompok 2 KKN-PPM Tematik Desa Dadapan ingin mengembangkan produk olahan tersebut menjadi produk yang digemari oleh seluruh penjuru dan tidak hanya di wilayah Desa Dadapan saja. Dengan memberikan dorongan kepada pemilik usaha untuk mengembangkan brand dan kemasan sehingga menjadi lebih menarik perhatian konsumen. Untuk mencapai tujuan yang diharapkan, penulis menggunakan metode penggalian informasi dan metode analisis data deskriptif dengan observasi dan wawancara. Dengan menggunakan brand dan kemasan baru menghasilkan produk keripik singkong Bu Rinda semakin banyak dikenal dan lebih memiliki banyak konsumen. Sehingga dapat meningkatkan penghasilan ekonomi Bu Rinda dan semakin banyak tenaga usaha yang dibutuhkan karena semakin banyaknya produk yang diproduksi. Harapannya branding dapat dijalankan secara berkelanjutan. Sehingga Desa Dadapan dapat menjadi Desa Sejahtera dan mandiri Berbasis Ekonomi Kreatif Melalui Pemanfaatan Ubi Singkong.
Pemberdayaan Masyarakat Desa Dalam Bidang Industri, Pendidikan Dan Kesehatan Guna Mendukung Program Desa Sejahtera Mandiri
Authors: Damayanti Dini Sri , Mayasari Eka Dewi , Prasetya Putri Rucitra Sectio , Hutama Adji Surya , Sulviadi Dana Sefrina , Ramadhan Ilham , Utama Bagas Sedyarsa , Nuril Laily Elviani , Hartaji Ivan , Zuhro Ayudya Nurhaliza
Published: October 2020

Desa Sukodono Kecamatan Dampit Kabupaten Malang merupakan salah satu daerah tujuan KKN Universitas Islam pada periode Pebruari 2020. Tujuan Kegiatan pengabdian kepada masyarakat (PPM) dalam rangka kegiatan KKN yang dilakukan oleh kelompok 63 adalah (1) Meningkatkan perekonomian masyarakat di Desa Sukodono dengan cara pembuatan produk olahan selai kopi, (2) Meningkatkan movitasi belajar siswa di SDN 1 Sukodono, dan (3) Meningkatkan tindakan preventif dan promotif stunting di Desa Sukodono. Kegiatan dilakukan melalui metode penyuluhan dan pelatihan, diskusi dan tanya jawab, serta demonstrasi secara langsung. Hasil akhir dari kegiatan menunjukkan bahwa kegiatan pengabdian kepada masyarakat (PPM) mampu memberikan motivasi dan perubahan pola fikir kepada masyarakat di Desa Sukodono terutama tentang bagaimana cara membuat produk olahan dari serbuk kopi, meningkatkan motivasi belajar siswa dan meningkatkan tindakan preventif dan promotif stunting. Kendala-kendala yang muncul dapat diatasi dengan metode pelatihan secara bertahap. Adanya MOU kerjasama dengan pemerintah daerah dan pemerintah desa perlu dilakukan untuk keberlajutan program secara kontinue dan dievaluasi keberhasilannya dalam meningkatkan ekonomi, kesejahteraan dan penurunan angka stunting di Kabupaten Malang.
Faith Tabernacle Congregation, the 1918–19 Influenza Pandemic and Classical Pentecostalism in Colonial West Africa
Authors: Mohr Adam
Published: October 2020

The 1918–19 influenza pandemic killed between 30 and 50 million people worldwide. In Sub-Saharan Africa, as Terence Ranger points out, the pandemic left an indelible mark, including the unforeseen emergence of anti-medical religious movements. None were as significant as Faith Tabernacle Congregation, the Philadelphia-based divine-healing church that spurred a massive revival in West Africa – and a network stretching from Ivory Coast to Nigeria – without ever sending missionaries. They evangelised through personal letters exchanged across the Atlantic, and Faith Tabernacle literature sent from Philadelphia to various leaders in West Africa. The 1918–19 influenza pandemic was the spark that led to the church's massive growth, from one small branch before the pandemic began in 1918 to 10,500 members and nearly 250 branches of Faith Tabernacle in West Africa at its zenith in 1926. After the church's rapid demise between 1926 and 1929, leaders of Faith Tabernacle established most of the oldest Pentecostal Churches in the Gold Coast and Nigeria – such as the Apostolic Faith, the Apostolic Church, the Christ Apostolic Church and the Assemblies of God (Nigeria). Classical Pentecostalism, therefore, is Faith Tabernacle's legacy in West Africa, while abstinence from orthodox medicine continued to be debated within these Pentecostal circles.
Redux Online Webinar 5: An Altered Landscape: The Impact of COVID-19 on University Presses
Authors: Cond Anthony , Kember Sarah , Barker Andrew , Hill Mandy
Published: October 2020

COVID-19 has created global upheaval in a way not seen since the Second World War. Among the sectors hardest hit has been education, with modes of teaching and research, a long-term trajectory of internationalisation and multiple revenue streams for universities disrupted in ways unthinkable twelve months ago. This final session of the Redux Online looks at the potential impacts on university presses of an altered landscape. Leaders from the library and university press worlds will examine how previous strategic priorities and practices have changed and will change for some of the key stakeholders in scholarly publishing. Recording of a live webinar held on 30 July 2020 as part of the Redux Online series.
MOTIVASI BELAJAR, KEMANDIRIAN BELAJAR DAN PRESTASI BELAJAR MAHASISWA BEASISWA BIDIKMISI DI UPBJJ UT BANDUNG
Authors: Hendrayana Angga Sucitra
Published: October 2020

This research aims to know level of learning motivation, independent learning and academic achievement Bidikmisi student scholarships at Indonesian Open University Regional office Bandung. This research is adescriptive research by taking samples of throughout Bidikmisi student scholarships at Indonesian Open University Regional Office Bandung consisting of study program in Accounting, Biology and Regional Planning City of the studentas much as 94 students at Registration Period 2013.2. The data in this study are learning motivation, independent learning, and the grade-point average (GPA). The data were analyzed descriptively to describe the level of learning motivation, independent learning, and grade-point average (GPA). The result of research shown that the average level of learning motivation are included in the category of very high. Independent learning showed that the average independent learning of students in the high category and the grade-point average (GPA) between1.75 to 3.85withan average GPAof 2.70.

Penelitian ini merupakan penelitian deskriptif dengan mengambil sampel seluruh mahasiswa beasiswa Bidikmisi di UPBJJ UT Bandung yang terdiri dari program studi Akuntansi, Biologi dan Perencanaan Wilayah Kota Masa registrasi 2013.2 sebanyak 94 mahasiswa. Variabel dalam penelitian ini adalah motivasi belajar, kemandirian belajar, dan indeks prestasi belajar (IPK). Analisis data dilakukan secara deskriptif untuk mengetahui gambaran tingkat motivasi belajar, kemandirian belajar, dan IPK mahasiswa. Hasil penelitian menunjukkan bahwa motivasi belajar termasuk dalam kategori sangat tinggi, dan kemandirian belajar rata rata termasuk dalam kategori tinggi, dan IPK berada dikisaran antara 1,753,85 dengan rata-rata IPK 2,70.
ANALISIS INDEKS KEPUASAN MASYARAKAT (IKM) TERHADAP PELAYANAN TUTORIAL TATAP MUKA DI UPBJJ-UT BENGKULU
Authors: Kristanti Dwi
Published: October 2020

Public services by the government in various sectors are sometimes perceived as not in line with public expectations. The purpose of this study was to analyze the quality of face-to-face tutorial services at Universitas Terbuka (UT) Regional Office in Bengkulu, using the Public Satisfaction Index (Indeks Kepuasan Masyarakat/IKM) method. This study used a quantitative descriptive approach. Data analysis techniques using the Public Satisfaction Index (IKM) approach, were calculated based on the weighted average value of each service element developed in the Regulation of Minister of State Aparatus and Bureaucratic Reform Number 16/2014. The findings of this study were that in general the assessment of public satisfaction index for Face to Face Tutorial held by UT Regional Office in Bengkulu obtained a Good Service criteria, with a Public Satisfaction Index value of 3.25 or converted to 81.16. It meant that the service performance was categorized as B (Good). Through continuous improvement, it was expected that the value of the Public Satisfaction Index (IKM) for Face-to-Face Tutorial services at UT’s Regional Office in Bengkulu can be maintained or improved in the following years.
Elements of the Persistence in Innovation: Systematic Literature Review
Authors: Arenas Juan Jesus , Gómez Juan Erasmo , Ortiz Efraín , Paz Freddy , Parra Carlos
Published: October 2020

The persistence of innovation is a topic that has been used in recent years. Companies must be in continuous production of innovations to achieve a competitive advantage in the market and for this, it is necessary to have elements that positively influence the persistence of innovating. The objective of the article is to describe the elements that positively influence the persistence of innovation through a systematic literature review in the range of the last 10 years (2010–2019). As a result, 34 articles were obtained and it was identified that investment in R & D, human resources and knowledge management positively influences the persistence of innovation.
High Exposure to Toxoplasma gondii and Neospora Spp. in Donkeys in Israel: Serological Survey and Case Reports
Authors: Tirosh-Levy Sharon , Steinman Amir , Minderigiu Avital , Arieli Ori , Savitski Igor , Fleiderovitz Ludmila , Edery Nir , Schvartz Gili , Leszkowicz Mazuz Monica
Published: October 2020

Toxoplasma gondii and Neospora spp. are closely related cyst-forming coccidian parasites, which infect various animal species and have considerable zoonotic and economic implications, respectively. Both parasites are endemic in Israel and have been reported to infect wild and domestic animals. This study was conceived to evaluate the serologic exposure of donkeys to these parasites. Serum samples were collected from 98 donkeys. Half of them (n = 49) were from animal shelters in Israel, and the rest (n = 49) were working donkeys from the Palestinian Authority. The donkeys were screened for the presence of anti-Toxoplasma and anti-Neospora antibodies by immunofluorescence antibody tests (IFATs). The seroprevalence of T. gondii and Neospora spp. was 94% and 70%, respectively, and 69% of the donkeys were exposed to both parasites. In addition, N. caninum tissue cysts were documented in two donkeys during post-mortem examination. This is the first report of the exposure of donkeys to T. gondii and Neospora spp. in the area. The high prevalence found in this study suggests that donkeys may have a role in the maintenance of these parasites in the area, thus serving as a source of infection for the definitive hosts.
Towards a More Robust Non-Rigid Robotic Joint
Authors: Pinto Vítor H. , Gonçalves José , Costa Paulo
Published: October 2020

The following paper presents an improved, low cost, non-rigid joint that can be used in both robotic manipulators and leg-based traction robotic systems. This joint is an improvement over the previous one presented by the same authors because it is more robust. The design iterations are presented and the final system has been modeled including some nonlinear blocks. A control architecture is proposed that allows compliant control to be used under adverse conditions or in uncontrolled environments. The presented joint is a cost-effective solution that can be used when normal rigid joints are not suitable.
NLOS Communication: Theory and Experiments in the Atmosphere and Underwater
Authors: Belov Vladimir V. , Juwiler Irit , Blaunstein Nathan , Tarasenkov Mikhail V. , Poznakharev Egor S.
Published: October 2020

In this paper, we present investigations of non-line-of-sight (NLOS) communication carried out in Russia and in collaboration with researchers in Israel. The theories of radiative transfer and linear systems provide the theoretical basis for this joint research, and experimental results demonstrate that maximal ranges for NLOS communication through atmospheric channels can reach hundreds of kilometers in the visible range and tens of kilometers in the ultraviolet (UV) range of the spectrum. Finally, we predict the range of bistatic underwater communication systems can reach hundreds of meters.
Low Dose Astaxanthin Treatments Trigger the Hormesis of Human Astroglioma Cells by Up-Regulating the Cyclin-Dependent Kinase and Down-Regulated the Tumor Suppressor Protein P53
Authors: Shin Juhyun , Saini Ramesh Kumar , Oh Jae-Wook
Published: October 2020

Astaxanthin (AXT) is a xanthophyll carotenoid known to have potent anti-cancer effects via upregulation of the intracellular reactive oxygen species (ROS) levels, which triggers apoptosis of cancer cells. While several studies have shown that AXT has potential as an anti-cancer drug, its effects in glioblastoma multiforme cells remain relatively unknown. In this study, we investigated the effects of AXT in the astroglioma cell lines U251-MG, T98G, and CRT-MG. We found that the response to AXT varied between cell lines. Moreover, U251-MG cells showed a specific hormetic response to AXT. At high concentrations (20–40 μM), AXT triggered apoptosis in U251-MG cells, as it has been previously shown in other cancer cell lines. However, low concentrations (4–8 μM) of AXT were found to upregulate the proliferative cell cycle. Furthermore, at low concentrations, AXT did not affect the intracellular ROS levels, while the superoxide dismutase activity increased moderately. Western blot analysis showed that treatment with a low concentration of AXT upregulated cyclin-dependent kinase (Cdk) 2 and p-Cdk2/3 levels and downregulated the expression of tumor protein p53. Thus, our results showed that AXT has a hormetic effect in the astroglioma cell line U251-MG.