bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimizing Competitiveness and Sustainability of Agribusiness SMEs through a Circular Economy Business Model
Authors: Ariyanti Riska , Taryana Asep
Published: February 2025

This study aims to optimize the competitiveness and sustainability of agribusiness SMEs in Indonesia through the application of the circular economy business model, using the design thinking approach, which includes the stages of empathize, define, ideate, and prototype. In light of increasing consumer awareness regarding sustainability, SMEs need to adapt in order to remain competitive. The circular economy offers solutions by utilizing waste as raw materials and extending product life cycles. This research is based on a literature review, direct discussions, and insights from a seminar presented by agribusiness owners, namely Mitra Tani Farm and Sangreat Natural Indonesia, to provide a deeper understanding of the application of the circular economy in the field. The findings indicate that circular economy-based strategies can improve operational efficiency and business resilience, while also providing positive environmental sustainability impacts, as demonstrated through case studies at Mitra Tani Farm and Sangreat Natural Indonesia. The prototype phase of this study outlines managerial implications that can be applied by agribusiness SMEs to enhance business sustainability. This article offers practical guidance for SMEs to achieve long-term sustainability while meeting market demands for responsible business practices.
The Effect of Awareness, Knowledge and Tax Sanctions on Taxpayer Motivation
Authors: Musda Muhammad Alqizhaz Faizal , Su’un Muh. , Sari Ratna
Published: February 2025

This study investigates the impact of tax awareness, tax knowledge, and tax sanctions on taxpayer motivation in fulfilling their tax obligations. Utilizing quantitative methods, the study finds that both tax awareness and tax knowledge significantly and positively influence taxpayer motivation, while tax sanctions also play an important role. The results show that tax awareness (p = 0.045) and tax knowledge (p = 0.000) contribute to intrinsic motivation, enhancing voluntary compliance by fostering a sense of social responsibility and understanding of taxes' role in national development. In contrast, tax sanctions, while effective in ensuring compliance through deterrence, act more as hygiene factors, promoting minimal compliance. Herzberg’s Motivation Theory supports these findings, highlighting that intrinsic motivator, such as awareness and knowledge, lead to long-term voluntary compliance, while sanctions only ensure basic compliance. The study emphasizes the importance of education and transparency in improving taxpayer understanding and motivation. Policymakers should prioritize initiatives that increase tax knowledge and awareness to cultivate a culture of compliance, rather than solely focusing on punitive measures. Ultimately, enhancing taxpayer motivation through education and awareness programs is critical to fostering sustainable tax compliance.
Evaluation of the Marine Space Utilization Program in North Kalimantan Province
Authors: Mursalin Syahrullah , Ibrahim Muh. Akmal , Ahmad Badu , Muhammad Sawedi
Published: February 2025

To carry out marine space utilization activities, every individual or entity operating permanently in territorial waters and jurisdiction must have a Conformity for Marine Space Utilization Activities (KKPR). Marine KKPR is a document that measures planned activities for suitability with the marine environment and seawater quality. This research aims to analyze the evaluation of marine space utilization programs in North Kalimantan Province. This research uses a descriptive qualitative approach with data collection methods, namely observation, in-depth interviews, and documentation. The informants in this research are the authorities and are directly involved in strategic management in the use of marine space in North Kalimantan Province. The results of the research show that the evaluation of the marine space utilization program in North Kalimantan Province still needs to be improved. This is because people still often ignore the legality of the business permits, they are running. Therefore, the government must continue to increase awareness regarding the importance of paying attention to business permits and also seaweed cultivation areas, so as not to disrupt shipping lanes.
Strategy of Implementing Blue Economy Policy in Developing Marine Tourism
Authors: Roem Muhammad , Ibrahim Muhammad Akmal , Nara Nurdin , Abdullah Muhammad Tang , Iskandar Didik
Published: February 2025

Promoting the blue concept economy in developing marine tourism to maintain and preserve the natural environment is not an easy thing, so a strategy is needed for its implementation. This study aims to analyze the implementation strategy of blue economy policy in developing marine tourism in Makassar City. This study uses a qualitative research approach with data collection methods, namely observation, in-depth interviews, and documentation. Informants in this study are parties who are authorized and directly involved in the management of marine tourism development in Makassar City. Data sources consist of primary and secondary data. The data analysis technique used is an interactive analysis model. The results of the study show that in the implementation of the blue economy policy on the development of marine tourism in Makassar City, the strategy as a pattern, position, perspective, and game has been quite good, only the strategy as a plan can be said to be still lacking. This is because of the legal products or policies and regulations related to the blue economy There is no policy yet, but there are practices for developing marine tourism that are oriented towards blue economy policy have been implemented especially in the coastal and beach areas of Makassar City.
Literature Review: Analysis of Saponins in Several Plants by HPLC Method and Its Utilization in Pharmaceutical Products
Authors: Prasasty Vony Intan
Published: February 2025

This research aims to determine the content of saponin compounds found in several types of plants and their benefits for health. This research uses computer equipment and the Google Scholar database, Research Gate, NJC journal, Science Direct. The type of research used is an article review using data sources directly collected by the researcher. The data search was carried out through a Google Scholar database, using the keywords "saponin levels and HPLC". The screening results that met the requirements were used as references for 25 articles. This research used plant samples using the dried leaves of the plant and then extracted using the ultrasonication method, then using centrifugation to obtain a clear solution. The saponin analysis of the samples was carried out. Using HPLC with various columns. From these results, the saponin compound was shown to appear at a retention time of 53.09 minutes with an avarage saponin amount of 1.05%. Pharmacological studies show that saponins have many important such as enhancing immunity, antitumor, anti-inflammatory, antifungal, and anti-viral actions, reducing blood glucose and lipids, antioxidants, improving cardiovascular function. From the results of research conducted by several researchers above, it can be concluded that saponin analysis in several plants can be carried out using HPLC with a wavelength of 205nm. Saponin compounds as secondary metabolites have many benefits in the pharmaceutical field, including anti-inflammatory, hepatoprotective activity, immunological improvement, anti-tumor, anti-aging, treatment of cerebral edema, lung injury, myocardial ischemia reperfusion injury and gastric ulcers.
Comparison of Treatment Characteristics of Chronic Suppurative Otitis Media
Authors: Pambagyo Septyan Wahyu , Pratama Ahmad Ardhani , Rismayanti Rismayanti , Sulaiman Andi Baso , Arifuddin Andi Tenri Sanna
Published: February 2025

To improve safe and quality health services, the Central Government has established the 2018 National Guidelines for Medical Services (PNPK) concerning the Management of Chronic Suppurative Otitis Media (CSOM), making it a reference, especially for Primary Health Care. To analyze the treatment characteristics of Chronic Suppurative Media Otitis (CSOM) in Mamajang Primary Health Care, Jongaya Primary Health Care, and Minasa Upa Primary Health Care, Makassar for January 2023-December 2023. This type of research is quantitative with a descriptive method through the cross-sectional study approach. The sampling technique used is total sampling. The data collection technique uses secondary data in the form of medical records of chronic suppurative media otitis (CSOM) patients at the Mamajang Primary Health Care, Jongaya Primary Health Care, and Minasa Upa Primary Health Care, Makassar for the 2023 visit year. Based on research conducted at the in Mamajang Primary Health Care, Jongaya Primary Health Care, and Minasa Upa Primary Health Care, Makassar City 72 people with Chronic Suppurative Media Otitis (CSOM) were found. There are differences in the treatment characteristics of the three Primary Health Care, namely the treatment at the Mamajang Primary Health Care is the most given combination of systemic antibiotics + systemic corticosteroids (46%). In contrast, in the Jongaya Primary Health Care, the most systemic antibiotic treatment (44%) was given. The Minasa Upa Primary Health Care has the most systemic antibiotic treatment (27%) and the combination of systemic antibiotics + systemic corticosteroids (27%) is given the most.
Analysis of Risk Factors for Anemia in Pregnant Women in the Sebabi Health Center Working Area
Authors: Multiansyah Multiansyah , Noor Meitria Syahadatina , Fujiati Fujiati , Suhartono Eko , Musafaah Musafaah
Published: February 2025

The prevalence rate of anemia among pregnant women in East Kotawaringin Regency in 2021 was 14%, in 2022 it decreased to 13.7% and in 2023 it increased to 16%. To determine the relationship between the incidence of anemia in pregnant women at Sebabi Health Center. The study was analytical observational using a cross sectional approach with a population of 300 people, 83 people were obtained as samples using proportionate random sampling technique. The research instrument was a questionnaire. The dependent variable: anemia. Independent variables: age, parity, knowledge, attitude, culture, education level and income. Bivariate analysis using chi square and multivariate using multiple logistic regression. The results showed there was a relationship between parity (p=0.000), knowledge (p=0.000), culture (p=0.004), and education level (p=0.000) while there was no relationship between age (p=0.174) attitude (p=0.147), and income (p=0.176) with the incidence of anemia in pregnant women. Parity was most associated with the incidence of anemia among pregnant women (exp(B)=10.061). There is an association between culture, parity, knowledge, education level and no association between age, parity, and income with anemia incidence. The parity variable is the most associated with the incidence of anemia among pregnant women.
The Influence of Family Support and Emotional Intelligence on Self-Acceptance in Kidney Failure Patients Undergoing Hemodialysis
Authors: Yanto Novri
Published: February 2025

The low level of self-acceptance in hemodialysis patients with kidney failure indicates the complexity of internal factors (such as emotional intelligence) and external factors (such as family support) that may influence the psychological quality of life of patients. The purpose of this study is to experimentally determine how family support and emotional intelligence affect self-acceptance in kidney failure patients undergoing hemodialysis. Using multiple linear regression analysis, this study sampled 100 kidney failure hemodialysis patients. The findings of the study suggest that emotional intelligence and family support play a significant role in the self-acceptance of kidney failure hemodialysis patients. Kidney failure patients may feel better about themselves during hemodialysis sessions by improving their emotional abilities and receiving greater family support.
The Role of Psychoeducation in Preventing Stunting: Tackling Early Marriage Culture in Adolescent
Authors: Kusuma Wardani Novita Eka , Harumi Ani Media , Sholika Siti Mar’atus
Published: February 2025

Stunting is a chronic nutritional issue threatening future generations, significantly influenced by early marriage practices. In East Java, Indonesia, early marriage has become a pressing concern, with a 10.44% increase in 2022, exceeding the national average. The region reported the highest number of early marriage dispensation requests in Indonesia, totaling 15,337 cases, or 29.4% of the national total. In the Madurese community, early marriage is often viewed as a customary practice, driven by unintended pregnancies and parental pressure. This study aims to evaluate the effectiveness of psychoeducation regarding stunting and early marriage culture in promoting stunting prevention behaviors among adolescent girls. A mixed-method approach was employed, using a quasi-experimental design with pre- and post-test groups, focusing on female adolescents aged 14-21 at the Wonoayu community health center. The independent variables include psychoeducation on stunting and early marriage culture, while the dependent variable is stunting prevention behavior. Data were collected using questionnaires for the quantitative aspect and in-depth interviews for the qualitative component. Results indicate significant improvements in stunting prevention behavior scores post-intervention. Psychoeducation effectively enhances knowledge about stunting's causes and preventive measures, enabling adolescents to take proactive steps. Furthermore, it fosters positive attitudes toward nutrition and reproductive health, encouraging healthier habits among participants.
Effectiveness of Topical Honey Application on Wound Healing: Literature Review Study
Authors: Tjongarta Winny , Antono Widi
Published: February 2025

The purpose of this study was to determine the wound healing process which has several phases. Another alternative for wound healing is to use honey which is known to have many bioactive components that have been proven effective and fast in the wound healing process. The method of writing literature is a literature review using several databases such as Pubmed, Google Scholar, Medline, Ebsco, Hindawi, Science Direct and Cochrane which were published in the last 10 years. The wound healing process has several phases, namely the hemostasis, inflammation, proliferation and remodeling phases. Each phase has its own healing time duration. Honey is a natural product formed from flower nectar and has been used by humans since ancient times around almost 5500 years ago. Honey has various benefits in the health sector. One of the benefits of honey is that it can prevent wound infections and accelerate the wound healing process. One study conducted by Yupanqui et al. stated that honey has natural antimicrobial properties and is a physical barrier at the wound site. Honey can be a topical therapeutic drug that is studied clinically for wound healing that contains antioxidants, antibacterials, antifungals, antivirals and other clinical benefits.
The Relationship between Hba1c Level and Total Cholesterol in Type 2 Diabetes Patients
Authors: Wulandari A Made Ayu Meita
Published: February 2025

Type 2 diabetes mellitus (T2DM) is a global health challenge with cardiovascular complications as the leading cause of morbidity and mortality. Monitoring HbA1c levels and lipid profiles are crucial parameters in evaluating cardiovascular risk in T2DM patients. This cross-sectional analytical study was conducted at the Gianyar Police Clinic from January to June 2024. A total of 60 T2DM patients meeting the inclusion criteria were analyzed using Pearson correlation and multiple linear regression tests to assess the relationship between HbA1c levels and total cholesterol. A significant positive correlation was found between HbA1c levels and total cholesterol (r=0.458, p<0.001). The correlation was stronger in patients with diabetes duration >10 years (r=0.512, p<0.001). 73.3% of patients had HbA1c >7% and 56.7% experienced total cholesterol abnormalities. Statin use showed a weaker correlation (r=0.378) compared to non-users (r=0.526). The majority of patients were in the 50-65 years age group (56.7%), with 63.3% having hypertension and 40% experiencing obesity as comorbidities. There is a significant relationship between HbA1c levels and total cholesterol in T2DM patients, with the strength of the relationship influenced by diabetes duration, statin use, and comorbidities. These findings emphasize the importance of simultaneous monitoring of both parameters in T2DM management, considering local socio-cultural factors.
Analysis of Plate Raw Material Control with Continuous Review System Method
Authors: Ganendra Devara Priya , Aryanny Enny
Published: February 2025

In today's era of globalization, many new companies have emerged, both companies engaged in services, manufacturing, and trade. One of the largest assets in the company PT. XYZ is raw material inventory. Raw material inventory is goods that are stored and used for the production process that are adjusted to the usage schedule. Therefore, in order to avoid high raw material inventory costs, the company must have a proper raw material inventory system by using the proposed method as a comparison, namely the continuous review system method. Plate inventory control was obtained in August 2023 - July 2024 with a total inventory cost using the company method of IDR 292,324,000 and the Continuous Review (s, Q) System method of IDR 144,722,000 with cost savings of IDR 147,602,000 and a cost reduction percentage of 50.4%. After forecasting the plate requirements for August 2023 - July 2024, plate inventory control was obtained with an order quantity of 6,560 sheets and a reorder point of 846 sheets with a total inventory cost of IDR 220,902,000.
Quality Control of Paint Tube Products Using Six Sigma and FMEA Methods
Authors: Khunaifi Nasywa Shabrina , Safirin Moch. Tutuk
Published: February 2025

PT XYZ is facingproduct quality challenges, especially visual defects in 25 kg pail tubes such as unmold tubes, jetting tubes, and IML on overlapping tubes with unmold tubes reached 55%. This study aims to analyze the main causes of defects in paint tube products at PT XYZ. The methods used are Six Sigma and FMEA with secondary data from the type of 25 kg tube defects in the last 3 months, involving 15 samples with 3 types of defects. The results show that material, mold, machine, and human factors contribute to defects. The Six Sigma value is 3.36, which is below standard. Recommendations for quality improvement are given to reduce the defect rate, with the highest RPN being 240 for unmold tubes.
Legal Accountability of Legal Subjects in the Criminal Act of Human Trafficking
Authors: Rio Saputra Manullang  , Janpatar Simamora  , Lesson Sihotang
Published: February 2025

Corporate human trafficking crimes represent a serious issue involving human rights violations in Indonesia and other countries. Although Indonesia has regulated this crime through Law No. 21 of 2007 on the Eradication of Human Trafficking (PTPPO), the enforcement of laws against human trafficking still faces significant challenges. This study aims to analyze the legal responsibility of corporations as subjects of law in human trafficking crimes and to understand the mechanisms of penalization against corporations involved in such crimes. The research method used is normative juridical with a literature study approach, gathering data from primary sources such as regulations and secondary sources including books, journals, and relevant literature. Data analysis is conducted deductively, beginning with fundamental legal principles applied to the phenomenon of human trafficking crimes. The study's findings show that corporations can be held collectively criminally liable if the crime is committed by their members acting on behalf of and in the interest of the corporation. The PTPPO law expands legal accountability for corporations to ensure more effective prevention and deliver justice for victims. Penalties that can be imposed on corporations include fines, imprisonment, and other social sanctions, focusing on direct, indirect, and leadership responsibilities. This study concludes that the implementation of criminal liability against corporations aims to encourage ethical corporate behavior, protect human rights, and strengthen global efforts to combat human trafficking.
The Effect of Metaphysics in Confounding Social and Community Development in Africa: Eclectic Contexts
Authors: Kang’ethe Simon Murote
Published: February 2025

The article discusses the effects of metaphysics on social and community development in the eclectic contexts of Africa. The researcher sourced information through a literature review of data across many English-authored journal articles, monographs, books, and book chapters. The journal papers were accessed from diverse Google search engines such as Google Scholar, EBSCOhost, Research Gate, Web of Science, ResearchGate, Scopus, Education Resources Information Center (ERIC), and Google Scholar. The findings presented the following metaphysics-related hurdles confounding social and community development: religious fanatism, faith from traditional healers in South Africa and Botswana, the unconventional practices of the white garment churches (Vapositori) of Zimbabwe and Bazezuru of Botswana, and the mythical environment embedded among the people of South Africa and Botswana. The paper concludes that people’s metaphysical beliefs influence social work development paradigms perniciously. This is because people see and interpret developmental reality from their metaphysical lenses. The paper challenges the African governments, in collaboration with other development partners, to strengthen their advocacy campaign to communities that subscribe to unconventional beliefs and ideologies so that they can undergo a paradigm shift to change their anti-developmental beliefs. The findings also widen the literature on the domain of metaphysics.

Keywords: Metaphysics, African Indigenous churches, traditional healers, pandemics, mythical environments, stigma and stigmatization.
The Nexus Between Good/Bad Governance and Citizens’ Participation in Nigeria’s Electoral Process
Authors: Ani Kelechi Johnmary
Published: February 2025

The place of the state in deciding the lives of the citizenry cannot be negotiated. This is because the first responsibility of the state is to protect the lives and properties of the citizenry. Ironically, the ability of the state to protect the lives and property of its citizenry would be measured on the level of governance impartation. When governance is good, the people will enjoy good life and smile but when the governance is poor, the masses will suffer. This study focuses on an assessment of the place of good/ bad governance in determining the nature of the electoral process in Nigeria. The study adopted a qualitative approach and used secondary data from other literature sources. The findings revealed that Nigeria is overtaken by bad governance and that has given fillip to electoral malpractice at all levels of the country’s election process. The study further revealed that the implication of the nexus between bad governance and electoral malpractice in the country include increased mortality rate, poverty and all manners of nepotism. The study concluded that bad governance in Nigeria has undermined the citizen’s participation in the electoral process. It recommends strategic steps like decentralization of the Nigerian state as well as digital elections and digital transmission of electoral results as the paths towards Nigerian national transformations. The study contributes to the wider body of literature in the area of politics, governance and policy analysis.

Keywords: Election, Good Governance, Citizens’ Participation, Nigeria
Mind the Gap. II. The Near-UV Fluxes of M Dwarfs
Authors: Jao 饒 Wei-Chun 惟君 , Youngblood Allison
Published: February 2025

Because of the continuous variations in mass, metallicity, and opacity, dwarf stars are distributed along the main sequence on optical and near-IR color–magnitude diagrams following a smooth polynomial. In this study, utilizing a catalog of crossmatched Galaxy Evolution Explorer (GALEX) and Gaia sources, we identify two distinct populations of M dwarfs in the near-UV (NUV) band on the M
NUV versus M

G
diagram. We also reveal a pronounced increase in the number of stars exhibiting high NUV fluxes near the spectral type M2 or M

G
 ~ 9.4, coinciding with the H2 formation in the atmosphere that improves the energy transportation at the surface. This suggests that certain yet-to-be-understood stellar mechanisms drive heightened activity in the NUV band around the effective temperatures of M2 and later types of M dwarfs. Through examination of archival Hubble Space Telescope spectra, we show that Fe ii line forests at ~2400 Å and 2800 Å dominate the spectral features in the GALEX NUV bandpass, contributing to the observed excess fluxes at a given mass between the two populations. Additionally, our investigation indicates that fast rotators and young stars likely increase in brightness in the NUV band, but not all stars with bright NUV fluxes are fast rotators or young stars.
Modeling the Impact of Moderate External UV Irradiation on Disk Chemistry
Authors: Gross Rachel E. , Cleeves L. Ilsedore
Published: February 2025

The chemistry within a protoplanetary disk is greatly affected by external radiation from the local stellar environment. Previous work has focused on extreme radiation fields, representative of the center of something like the Orion Nebula Cluster. However, even in such environments, many disks exist at the edges of a cluster where the lower stellar density leads to radiation fields weaker by orders of magnitude compared to the center. We present new chemical models of a T Tauri disk in the presence of a moderately increased interstellar radiation field (ISRF). Such an environment has a background UV strength 10–100 times higher than the galactic average ISRF. Moderate radiation fields are among the most prevalent disk-harboring environments and have interesting implications for the chemistry of the outer disk radii. We find that the external UV radiation creates an outer ionization front that impacts the cold disk chemistry to varying degrees, depending on outer disk structure. Certain molecules like C+, N2H+, C, and CS are more strongly impacted by the ISRF in their abundance, column density, and observable emission. Other abundant species like HCO+ and CO are less affected by the external UV flux in the outer disk under such moderate UV conditions. Further, we demonstrate that the chemistry occurring in the inner tens of au is relatively unchanged, which suggests that even in moderately externally irradiated disks the inner disk chemistry may be more similar to isolated disks like those in, e.g., the Taurus and Lupus star-forming regions.
Flux-rope-mediated Turbulent Magnetic Reconnection
Authors: Russell Alexander J. B.
Published: February 2025

We present a new model of magnetic reconnection in the presence of turbulence. The new model differs from the Lazarian–Vishniac turbulent reconnection theory by emphasizing the role of locally coherent magnetic structures, whose existence is shown to be permitted by the properties of magnetic field line separation in turbulent plasma. Local coherence allows storage of magnetic helicity inside the reconnection layer in the form of locally coherent twisted flux ropes. We then introduce the “Alfvén horizon” to explain why the global reconnection rate can be governed by locally coherent magnetic field structure instead of by field line wandering, formally extending to 3D the principle that reconnection can be made fast by fragmentation of the global current layer. Coherence is shown to dominate over field line dispersion if the anisotropy of the turbulence at the perpendicular scale matching the thickness of a marginally stable current layer exceeds the aspect ratio of the current layer. Finally, we conjecture that turbulence generated within the reconnection layer may produce a critically balanced state that maintains the system in the flux-rope-mediated regime. The new model successfully accounts for the major features of 3D numerical simulations of self-generated turbulent reconnection, including reconnection rates of 0.01 in resistive MHD and 0.1 with collisionless physics.
Description of two new species of Ophiocordyceps: O. sinocampes and O. cystidiata (Ophiocordycipitaceae, Hypocreales) from typical karst landform forests in Guizhou, China
Authors: Xu Zhong-Shun , Deng Li-ping , Wang Hai-Yan , Tian Hui-Ling , Qu Jiao-Jiao , Dai Yong-dong , Zou Xiao
Published: February 2025

Karst habitats are hotspots of diversity and endemism. Their naturally fragmented distributions across broad geographic landscapes have led to a complex array of smaller evolutionary ecosystems. Comprehensive biodiversity assessments of karst habitats have revealed that these ecosystems contain a high level of endemism. During a survey of cordycipitoid fungi in the karst region of southwest Guizhou, China, we identified and proposed two new species, based on morphology and multi-locus (nrSSU, nrLSU, tef, rpb1, and rpb2) phylogenetic analyses. O. cystidiatasp. nov. is characterized by gray-white to yellow fertile part, verrucose phialides, and conidia enveloped in a cystic thickened mucus sheath, distinguishing it from other species. O. sinocampessp. nov. is distinguished by long tapering phialides with inflated bases. Phylogenetic analyses using five loci reveal that O. cystidiata shares a close relationship with O. fenggangensis, O. musicaudata, O. alboperitheciata, and Hirsutella kuankuoshuiensis, while O. sinocampes is closely related to O. multiperitheciata and H. strigosa. Herein, we completed the descriptions, illustrations and molecular phylogeny of these two new species. The host diversity of O. sinocampes has also been documented within the orders Lepidoptera and Coccoidea. Our research further enriches the diversity of cordycipitoid species in the typical karst landform areas of Guizhou, China.
Éditorial. L’éco-anxiété en question, ou comment faire face à la destruction de la Terre ?
Authors: Bernateau Isée
Published: February 2025

L’ampleur actuelle et inédite de la crise environnementale mondialisée donne lieu depuis une dizaine d’années à une efflorescence d’angoisses écologiques, qui se sont peu à peu subsumées sous le terme d’éco-anxiété. Celle-ci appartient à la catégorie freudienne des « angoisses devant un danger réel », réactionnelles à un danger externe. Elle est en ce sens une angoisse adaptée, bien distincte de l’angoisse névrotique. Et pourtant elle est susceptible de devenir invalidante sur le plan individuel, au sein d’un monde dans lequel déni et déréalisation semblent constituer la réponse collective la plus répandue au phénomène. Cette destruction questionne en profondeur notre destructivité : pour quelles raisons psychiques les êtres humains s’en sont-ils pris à la Terre elle-même, alors même qu’ils dépendent drastiquement du maintien de ses écosystèmes pour leur survie ? Assiste-t-on à un nouveau déchaînement des pulsions de mort ou à une nouvelle issue catastrophique du conflit entre l’homme et la culture ?
Climatoscepticisme et post-vérité climatique : la banalité du déni ?
Authors: Troubé Sarah
Published: February 2025

La prolifération, depuis l’ère du numérique, des fake news et théories du complot a mis en lumière la banalité du déni, dans des incarnations bien plus larges que celles de la clinique des psychoses, de la perversion ou du traumatisme. Le déni complotiste semble en même temps emprunter certains de ses traits à ces formes cliniques du déni, dans sa tentative d’aménager une position viable face à l’effraction d’une réalité intolérable et inélaborable. La menace écologique, en confrontant à la perspective d’une réalisation des fantasmes de fin du monde et de destructivité, est particulièrement à même de venir brouiller la distinction entre réalité fantasmatique, réalité fictionnelle et réalité historique. Si les théories climatosceptiques se distinguent peu, dans leur contenu, des autres incarnations de l’imaginaire du complot, la menace écologique pointe néanmoins vers d’autres formes spécifiques de refus de la réalité. Ne pas refuser la réalité de la menace écologique exige alors de prendre acte du caractère radical de la perte de réalité qu’elle implique, ce qui soulève la question de savoir dans quelle mesure il s’avère possible, au plan psychique, de représenter cette perte de réalité et, au plan métapsychologique, de saisir à la fois sa radicalité et son caractère inédit.
Geografía electoral de Chile: comportamiento del electorado chileno entre 1932 y 1992
Authors: González Leiva José Ignacio
Published: February 2025

No disponible.
Implicaciones demoespaciales de la pandemia de COVID-19 en España
Authors: Sánchez Aguilera Dolores , Esparcia Javier , Recaño Valverde Joaquín , Fernández-Mayoralas Gloria
Published: February 2025

No disponible
Eco-Stories That Stick
Authors: Roopak Roopendra , Bandyopadhyay Chinmoy , Pradhan Swikruti
Published: February 2025

This case study examines Rustic Hue® (RH), a sustainable fashion brand committed to ethical practices, cultural heritage, and environmental protection. RH faced challenges in effectively communicating their orientation and commitment to social, economic and environmental sustainability while differentiating themselves in a crowded market. To overcome this challenge, RH implemented strategic digital storytelling in an innovative manner. They utilized their own digital media, including social media and the website, to showcase collaborations with weaving communities, highlight design innovations and customer testimonials. These approaches helped RH to foster trust, transparency, enhanced market recognition, and establish cultural relevance. Beyond sharing product-oriented stories, they also emphasize and publish on environmental responsibility through their “Jugaad” line, which promotes upcycling and zero-waste practices. Furthermore, RH documents the lives and practices of these communities and shares research findings to promote public awareness and appreciation.
Economic Model and Renewable Energy Strategy Transformation Moving From Linear to Circular Methods
Authors: El Ouardi Mohamed , Abouri Mariyem , Mabrouki Jamal , Zair Touriya , Alaoui El Belghiti Mohammed
Published: February 2025

The shift from a linear to a circular economic model is crucial for transforming renewable energy strategies towards sustainability and efficiency. Traditional linear approaches, which involve “take, make, dispose,” are unsustainable due to finite resources and environmental concerns. Circular methods focus on recycling, reusing, and regenerating materials, optimizing resource utilization, minimizing waste, and reducing energy systems' environmental footprint. This paper explores the theoretical and practical applications of circular economic principles in renewable energy, presenting case studies and innovative technologies. The analysis shows that adopting circular economic methods can enhance economic resilience, reduce resource dependency, and provide significant environmental benefits, providing valuable insights for policymakers, industry leaders, and researchers.
Sustainable Pathways
Authors: Elshaikh Ahmed , Abdo Gamal , Salih Abdin , Ladisa Gaetano , Bogliotti Claudio , Sokrab Ishraga , Barsi Mohammed , Mabrouki Jamal
Published: February 2025

The Gezira Scheme, one of the world's largest irrigation projects, faces complex challenges in managing its water-energy-food nexus while ensuring agricultural sustainability. This study investigates the implementation of Best Management Practices (BMPs) within the scheme, focusing on soil fertility, water management, and energy efficiency. Through development of a comprehensive framework, key findings emerge regarding the importance of BMPs in enhancing agricultural productivity. Strategies such as soil enhancements, water-efficient irrigation techniques, and improved seeds adoption are identified as critical for promoting sustainable production practices within the scheme. In conclusion, sustainable agriculture practices not only ensure the long-term viability of agricultural production within the scheme but also contribute to broader societal goals such as food security, poverty alleviation, and environmental conservation.
Ensemble Learning Techniques for Advanced Threat Detection in Complex Data Environments for Smart Education
Authors: Dhiman Virender
Published: February 2025

As educational environments increasingly leverage digital technologies, they become more susceptible to a myriad of cyber threats. This chapter explores the application of ensemble learning techniques for advanced threat detection in complex data environments, particularly within smart education frameworks. Ensemble learning, which combines multiple machine learning models to enhance predictive performance, provides a robust solution for identifying and mitigating cyber threats in real-time. By analyzing diverse datasets from various educational technologies, the chapter illustrates how these techniques can improve the accuracy and efficiency of threat detection systems. Furthermore, it discusses the integration of ensemble methods with emerging technologies such as IoT, big data analytics, and AI to create a comprehensive security framework tailored for smart education. Case studies demonstrating successful implementations highlight the effectiveness of ensemble learning in adapting to the evolving threat landscape.
Braille-Lippi Numbers and Characters Detection and Announcement System for Blind Children Using KSK Approach
Authors: Kazi Kutubuddin Sayyad Liyakat
Published: February 2025

In order to develop a Braille-Lippi character recognition system, a number of different strategies and procedures have been utilized, with the KSK Approach being the primary tool utilized. When doing analysis, the KSK Approach makes use of DT, ANN, and K-NN classifiers. In comparison to other computational methods, the KSK Approach is superior in terms of its efficiency and reliability when it comes to recognising Braille characters. The page contains the results of testing and system development, as well as the technique, design, and architecture of the Braille character recognition system, which has a 99% accuracy rate. This also makes it possible to use the Voicing System, which is responsible for announcing the letter that has been recognized.
Challenges in Managing Graves’ Disease with Coexisting Acute-on-chronic Liver Disease
Authors: Jabir Said , Kiran Bangaru Sai , Neelaveni Kudugunti , Thomas Raveen Titus
Published: February 2025

ABSTRACT

Deranged liver enzymes in a patient with thyrotoxicosis can result from the impact of hyperthyroidism on liver function, side effects of antithyroid drugs, or coexisting chronic liver disease. These overlapping causes can complicate both diagnosis and treatment, requiring careful consideration in management strategies. We present the case of a 28-year-old female who presented with coexisting Graves’ disease and acute-on-chronic liver disease. The timely initiation and careful consideration of various medical management strategies were essential for the successful treatment and favorable prognosis of the patient.
Complexity classes of Polishable subgroups
Authors: Lupini Martino
Published: February 2025

In this paper we further develop the theory of canonical approximations of Polishable subgroups of Polish groups, building on previous work of Solecki and Farah–Solecki. In particular, we obtain a complete characterization of the Borel complexity class of a Polishable subgroup in terms of its canonical approximation. As an application we provide a complete list of all the possible Borel complexity classes of Polishable subgroups of Polish groups, or equivalently of the ranges of continuous group homomorphisms between Polish groups. We also provide a complete list of all the possible Borel complexity classes of the ranges of: continuous group homomorphisms between non-Archimedean Polish groups; continuous linear maps between separable Fréchet spaces; and continuous linear maps between separable Banach spaces.
Characteristics and therapeutic strategies for familial gastrointestinal stromal tumors
Authors: Liu Yuan , Li Xiao-Feng
Published: February 2025

This editorial discusses Wang et al 's article on familial gastrointestinal stromal tumors (GISTs). We read with great interest this article concerning the diagnosis, treatment, and post-treatment management of patients with familial GISTs. The actual incidence of GISTs may be underestimated due to diagnostic limitations and the long-term low-risk behavior of some GISTs. The molecular landscape of GISTs is primarily driven by mutations in the KIT and platelet-derived growth factor receptor alpha (PDGFRA ) genes. A subset of GISTs without these mutations known as wild-type GISTs, may harbor other rare mutations, impacting their response to targeted therapies. Clinically, patients with GISTs present with non-specific symptoms, often leading to delayed diagnosis. Genetic predispositions in familial GISTs provide insights into the genetic architecture and extragastrointestinal manifestations of GISTs. Management has evolved from surgical interventions to molecular-based therapies using tyrosine kinase inhibitors. The management of GISTs, especially in familial cases, requires a multidisciplinary approach. Cases of different gene mutations were reported in the same family, suggesting that incorporating genetic testing into routine clinical practice is crucial for the early identification of high-risk individuals and the implementation of tailored surveillance programs.
Combination therapy strategy based on selective internal radiation therapy as conversion therapy for inoperable giant hepatocellular carcinoma: A case report
Authors: Hao Ming-Zhi , Lin Hai-Lan , Hu Yu-Bin , Chen Qi-Zhong , Chen Zhang-Xian , Qiu Lin-Bin , Lin Duan-Yu , Zhang Hui , Zheng De-Chun , Fang Zhu-Ting , Liu Jing-Feng
Published: February 2025

BACKGROUND

Hepatocellular carcinoma (HCC) has become a growing health concern globally. Microvascular invasion and high tumor burden are key factors limiting the curative effect of selective internal radiation therapy (SIRT).

CASE SUMMARY

This case study reports a 49-year-old woman who was diagnosed with China Liver Cancer Staging (CNLC) IIIa HCC and > 15 cm tumor diameter. Initially, due to insufficient future liver remnant and vascular invasion, the tumor was unresectable; however, radical hepatectomy was performed after successful conversion therapy with SIRT using yttrium-90 (90Y) resin microspheres followed by hepatic arterial infusion chemotherapy (HAIC) with tyrosine kinase inhibitor (TKI) and anti-programmed death-1 (PD-1) antibody. SIRT using 90Y resin microspheres was given by the right hepatic artery and chemoembolization was simultaneously performed in the tumor’s feeding vessels from the right diaphragmatic artery. HAIC was followed every three weeks with lenvatinib and tislelizumab. At 4 months post-SIRT, the tumor was downstaged to CNLC Ib and the patient successfully underwent hepatectomy. The histopathological examination of the resected specimen showed extensive necrosis.

CONCLUSION

This case study provides evidence for an integrated treatment strategy combining SIRT and HAIC with TKI and anti-PD-1 antibodies for patients with large HCC and microvascular invasion. Further confirmatory trials are required in the future.
Heterochronic gastric adenosquamous carcinoma combined with colonic adenoma: A case report
Authors: Liu Gui-Jiang , Long Xiao-Yi , Zhang Fei , Ren Tao , Xia Xun
Published: February 2025

BACKGROUND

Metachronous gastric cancer usually refers to a tumor that occurs in the stomach more than half a year after esophageal cancer surgery, and metastasis of primary esophageal cancer should be excluded. There are few reports of metachronous gastric adenosquamous carcinoma with signet ring cell carcinoma combined with early tubular adenoma of the colon after esophageal cancer surgery, which has a high degree of malignancy. This is also the reason for the poor treatment results.

CASE SUMMARY

A 54-year-old male patient was admitted to the hospital with “dysphagia obstruction”. Seven years ago, the patient was diagnosed with well-differentiated squamous cell carcinoma in the middle esophagus (T4N1M0 stage) and left gastric lymph node metastasis. In the final resection of the esophageal cancer, no residual cancer tissue was found in the esophageal and gastric stump. The patient’s medical history 7 years ago (preoperative gastroscopy and other examinations) revealed no gastric tumor. Combined with the patient’s history, the diagnosis of recurrent esophageal cancer was made on this admission. The final pathological results were surprising: Metachronous gastric adenosquamous carcinoma with signet ring cell carcinoma combined with early tubular adenoma of the colon. Considering the high malignancy of the tumor, the complexity of the second operation, and many complications, the patient received chemotherapy.

CONCLUSION

He had a history of esophageal cancer resection. Gastroenteroscopy should be performed simultaneously to avoid missed diagnosis and misdiagnosis.
Irreversible electroporation combined with anti-programmed cell death protein 1 therapy promotes tumor antigen-specific CD8+ T cell response
Authors: Ma Yang-Yang , Wang Xiao-Hua , Zeng Jian-Ying , Chen Ji-Bing , Niu Li-Zhi
Published: February 2025

BACKGROUND

Irreversible electroporation (IRE) is a novel local tumor ablation approach with the potential to activate the host’s immune system. However, this approach is insufficient to prevent cancer progression, and complementary approaches are required for effective immunotherapy.

AIM

To assess the immunomodulatory effects and mechanism of IRE combined anti-programmed cell death protein 1 (PD-1) treatment in subcutaneous pancreatic cancer models.

METHODS

C57BL-6 tumor-bearing mice were randomly divided into four groups: Control group; IRE group; anti-PD-1 group; and IRE + anti-PD-1 group. Tumor-infiltrating T, B, and natural killer cell levels and plasma concentrations of T helper type 1 cytokines (interleukin-2, interferon-γ, and tumor necrosis factor-α) were evaluated. Real-time PCR was used to determine the expression of CD8 (marker of CD8+ T cells) in tumor tissues of the mice of all groups at different points of time. The growth curves of tumors were drawn.

RESULTS

The results demonstrated that the IRE + anti-PD-1 group exhibited significantly higher percentages of T lymphocyte infiltration, including CD4+ and CD8+ T cells compared with the control group. Additionally, the IRE + anti-PD-1 group showed increased infiltration of natural killer and B cells, elevated cytokine levels, and higher CD8 mRNA expression. Tumor volume was significantly reduced in the IRE + anti-PD-1 group, indicating a more pronounced therapeutic effect.

CONCLUSION

The combination of IRE and anti-PD-1 therapy promotes CD8+ T cell immunity responses, leading to a more effective reduction in tumor volume and improved therapeutic outcomes, which provides a new direction for ablation and immunotherapy of pancreatic cancer.