bluuebunny/crossref_metadata_2025 huggingface dataset:
Review: complement receptor 1 therapeutics for prevention of immune hemolysis
Authors: Yazdanbakhsh K.
Published: May 2021

The complement system plays a crucial role in fighting infections and is an important link between the innate and adaptive immune responses. However, inappropriate complement activation can cause tissue damage, and it underlies the pathology of many diseases. In the transfusion medicine setting, complement sensitization of RBCs can lead to both intravascular and extravascular destruction. Moreover, complement deficiencies are associated with autoimmune disorders, including autoimmune hemolytic anemia (AIHA). Complement receptor 1 (CR1) is a large single-pass glycoprotein that is expressed on a variety of cell types in blood, including RBCs and immune cells. Among its multiple functions is its ability to inhibit complement activation. Furthermore, gene knockout studies in mice implicate a role for CR1 (along with the alternatively spliced gene product CR2) in prevention of autoimmunity. This review discusses the possibility that the CR1 protein may be manipulated to prevent and treat AIHA. In addition, it will be shown in an in vivo mouse model of transfusion reaction that recombinant soluble forms of CR1 can reduce complement-mediated RBC destruction, thereby prolonging survival of transfused RBCs. It is proposed that CR1-based therapeutics have potential for effective and safe prophylactic short-term use and for treatment of hemolytic transfusion reactions.
Immunohematology

2005;21:109–118.
A bicarbonate anion-dependent anti-’N’ MoAb
Authors: Iyer Y.S. , Vasantha K. , Joshi S.R. , Patwardhan M. , Pujari V. , Jadhav S. , Mohanty D.
Published: May 2021

While studying the serologic characteristics of certain monoclonal blood group antibodies, we observed a hybridoma clone (5A- 11E10) with anti-N–like serologic specificity that was dependent on the presence of the bicarbonate anion. The diluted cell culture supernatant preferentially agglutinated M–N+ RBCs by immediate spin. This supernatant also agglutinated M–N+ RBCs that had been treated with trypsin or sialidase (to remove N-reactivity), suggesting anti-’N’ activity. Anti-’N’ specificity was confirmed by the supernatant’s non-reactivity with N+ RBCs treated with papain (to remove ‘N’ reactivity) or with (‘N’-negative) M+N–U– RBCs. The requirement for bicarbonate in the MoAb’s formulation was not a function of pH. Both sodium and ammonium bicarbonate supported agglutination, but neither sulfate nor carbonate was effective.
Case report: exacerbation of hemolytic anemia requiring multiple incompatible RBC transfusions
Authors: Svensson A.M. , Bushor S. , Fung M.K.
Published: May 2021

RBC transfusions in a patient with a history of autoimmune hemolytic anemia (AIHA) can represent both a laboratory and a clinical challenge. The development of high-titer low-avidity antibodies and antibodies to high-frequency antigens may further impair the ability to identify compatible donor RBCs. Not infrequently, incompatible RBCs must be used and the desire to increase oxygen carrying capacity conflicts with the desire to avoid exacerbating the autoimmune hemolytic process with RBC transfusions. A 66-year-old Caucasian female with coronary artery disease and a history of refractory AIHA had recently developed anemia and required multiple RBC transfusions. The patient had maintained adequate RBC counts with erythropoietin and prednisone therapy for the previous 16 months. With the recent worsening of her hemolytic anemia, she had developed angina that was treated with RBC transfusions in an outpatient setting. However, her angina increased as her RBC counts decreased, leading to hospital admission for further management of her hemolytic anemia and angina. She subsequently required multiple incompatbile RBC transfusions despite increased prednisone therapy and did not improve until after coronary artery stent placement and high dose IVIG therapy. This case demonstrates the usefulness of early patient phenotyping in a case of accelerating hemolytic anemia to aid in donor RBC selection, the value of communicating with clinicians and the patient regarding the use of least-incompatible RBCs, and the importance of optimizing the patient’s clinical condition to avoid ischemia. In addition, it demonstrates the value of repeated attempts with IVIG treatment despite previous refractoriness to this treatment.
Water leakage detection and localization using hydraulic modeling and classification
Authors: Mohammed Eliyas Girma , Zeleke Ethiopia Bisrat , Abebe Surafel Lemma
Published: May 2021

A significant percentage of treated water is lost due to leakage in water distribution systems. The state-of-the-art leak detection and localization schemes use a hybrid approach to hydraulic modeling and data-driven techniques. Most of these works, however, focus on single leakage detection and localization. In this research, we propose to use combined pressure and flow residual data to detect and localize multiple leaks. The proposed approach has two phases: detection and localization. The detection phase uses the combination of pressure and flow residuals to build a hydraulic model and classification algorithm to identify leaks. The localization phase analyzes the pattern of isolated leak residuals to localize multiple leaks. To evaluate the performance of the proposed approach, we conducted experiments using Hanoi Water Network benchmark and a dataset produced based on LeakDB benchmark's dataset preparation procedure. The result for a well-calibrated hydraulic model shows that leak detection is 100% accurate while localization is 90% accurate, thereby outperforming minimum night flow and raw- and residual-based methods in localizing leaks. The proposed approach performed relatively well with the introduction of demand and noise uncertainty. The proposed localization approach is also able to locate two to four leaks that existed simultaneously.
Growth of science in activated sludge modelling – a critical bibliometric review
Authors: Ahnert Markus , Krebs Peter
Published: May 2021

In this paper, the tool of bibliometric analysis is applied to the field of activated sludge modelling and its suitability as a first step of a literature analysis is assessed. The analysis is applied to the total dataset considered as well as a time-based classification. It can be shown that this tool is very well suited to filtering the relevant authors and publications, thus enabling a subsequent visual review. The methodology presented can also be applied to sub-disciplines or other subject areas. However, the sole use of the multiple statistical and visual tools is critically questioned. Thus, misinterpretations and apparent findings can result from structural problems in the data or parameters used. Not all of the metrics used are suitable for finding relevant publications, but rather for ranking the criteria studied. However, the latter represents the most widespread application of bibliometrics. From the analysis of the keywords, it could be deduced that there has been a temporal shift from fundamental model aspects to detailed questions such as the integration of sorption and adsorption processes or anaerobic digestion. The modelling of biological phosphorus removal has also surprisingly lost a great amount of importance in the scientific literature.
Family Physicians' Awareness of Skin Cancer and Sun Protection Practices
Authors: ARSLAN Hatice Nilden , KEMAL Yasemin
Published: May 2021

Objective: The objective of this study was to determine the knowledge level of family physicians about skin cancer and their attitudes and behaviors about sun protection. Methods: The sample of this study was composed of 295 family physicians who worked in Samsun province and participated in in-service trainings organized by the Provincial Health Directorate in March 2019. A questionnaire form consisting of questions on sociodemographic characteristics, attitudes and behaviors about sun protection was applied to the participants. Result: A total of 295 family physicians, 64.7% male and 35.3% female, participated in the study. Most of the physicians (87.8%) expressed that they tried to protect from sunlight. Women (68.3%) used sunscreen lotions/creams more frequently than men (41.4%). Those who had 2 and more severe sunburns throughout their lifetime (51.5%) stated that they described themselves at higher risk than those who did not (36.2%) which was statistically significant (p<0.05). The reasons of the physicians for application to a dermatologist were: 47(15.9%) had asymmetrically shaped, irregularly structured moles larger than 5 mm, 37(12.5%) had suspected presence of moles, 11(3.7%) wanted whole body examination for moles, 20(6.8%) requested advice on daily skin care and prevention of skin aging. Conclusion: Awareness studies should be carried out on the harmful effects of the sun and early diagnosis of skin cancer especially for family physicians, healthcare professionals and other parts of the society. In addition, considering that visual evaluation has a role in the diagnosis of skin cancer, it will be useful for family physicians to inform their patients about the detrimental effects of the sun and self-skin examination.
Layu Sebelum Berkembang: Studi Kasus Kerjasama Sister City Malang dengan Fuqing dalam Komoditas Kedelai
Authors:   Universitas Muhammadiyah Malang, Khairi Naufal Fikhri , Mulyanor Amaliya , Sari Fitria Winda , Zhafira Nurul
Published: May 2021

The purpose of this paper is to determine the factors that have stopped the Sister City cooperation between Malang City and Fuqing City in the field of soybean commodity. Fulfilling the need for imported soybeans is important for Malang, because it is well-known for its many ‘Keripik Tempe’ producers or commonly called ‘IKM Tempe’, so that the potential for Fuqing imported soybean is important to be realized. The study used a qualitative descriptive method, and used the Paradiplomacy Concept and the Sister City Concept in explaining the cooperation between Malang City and Fuqing City. The results obtained were the cooperation between sister city Malang City and Fuqing City in the field of soybean commodity which ‘failed’ because soybeans from Fuqing were of lower quality than soybeans imported from United States and had large production losses, so that the IKM Tempe in Malang preferred to use imported United States soybeans and stopped the use of imported Fuqing soybeans. Until now, the two city governments have not been heard meeting to discuss this issue, which makes the city government as a sub-state actor not yet having a strong commitment to this cooperation.
The Two Faces of Russia Foreign Policy toward China and Taiwan
Authors:   Universitas Brawijaya, Fahadayna Adhi Cahya
Published: May 2021

Russia, as one of the key actors in international politics, faces problematic issues in Chinese-Taiwan Relations. As a significant player, Russia reserves a close and stable relationship with China. However, Russia could not avoid Taiwan's significant role in Northeast Asia, especially its role in allying with the West. Taiwan undoubtedly offers a promising prospect for the Russian economy, but political relations with Taiwan could not significantly contribute to Russian FP. In this paper, Russian foreign policy will be examined on both sides, Russian foreign policy toward China and Russian foreign policy toward Taiwan. The purposes of this paper are trying to analyze the Russian foreign policy dilemma toward China-Taiwan relation. The analysis of this paper will focus on President Vladimir Putin as the decision-maker and explore all circumstances that will influence the decision-making process. The level of analysis implemented in this paper is domestic politics that significantly contribute to Russian foreign policy decision-making. This paper will gather secondary data from the news, journal, and book as the primary sources. The paper's outcome is analyzing Russian foreign policy's dilemma and exploring how Russian foreign policy toward current dynamics of China-Taiwan Relations.
International Support for Democracy in Nepal
Authors: Guragain Yuba Raj
Published: May 2021

This study explores the roles of international communities in the democratization process particularly in the post-conflict contexts of Nepal. Based on the main courses of Constituent Assembly Elections of 2008 and 2013 on the background of the civil war (1996 - 2006) and peace process, the analyses of related data showed that international community assisted not only to the peace process through playing different roles such as of a facilitator, a technical supporter, a monitor, a diplomatic good office in the peace process but also as a technical and generous supporter to Election Commission for managing free, fair and credible elections. The support was to the Election Commission, the peace process, to the legislature parliament and all these have made more contributions on institutional and managerial aspects for democracy promotion while equal focus has to be on the people’s level for deliberative democracy.
Life Cycle Assessment (LCA) Analysis of Concrete Slab Construction For Estimating The Environmental Impact
Authors:   Brawijaya University, Rakhmawati Annisa Nur , Devia Yatnanta Padma ,   Brawijaya University, Wijatmiko Indradi ,   Brawijaya University
Published: May 2021

Global warming and air pollution become one of the environmental issues facing the world. the construction sector consumes about 40% of total global energy. Many strategies have been adopted to improve the efficiency of building construction to reduce material consumption and carbon emissions. One way to find out the environmental impact and carbon emissions produced is with a Life Cycle Assessment (LCA). This study aims to predict the environmental impact of concrete slab construction in two-story dwellings using the Life Cycle Assessment (LCA) approach of the material used with the help of software, namely Simapro 9.0. The scope of the study is the cradle to the grave. The results of the SimaPro 9.0 concrete plate construction analysis, especially in global warming are 1.02, E+07 kg CO2 eq. The biggest contribution to the manufacture of concrete slabs is the casting process with a value of 1.00, E+07 kg CO2 eq.
Pemetaan Daya Dukung Fondasi Dangkal di Wilayah Universitas Jember Berbasis CPT (Cone Penetration Test)
Authors:   Universitas Jember, Hidayat Bagus Rahmad , Hernu Suyoso Paksitya Purnama ,   Universitas Jember, Suyoso Hernu ,   Universitas Jember
Published: May 2021

This research aims to make a bearing capacity distribution map of shallow foundations (footplate), which is to provide convenience in terms of examining substructure buildings planned by the consultant by the owner. Spatial concepts method, ArcGIS and kriging, are used to simplify the analysis stage in making bearing capacity maps. Bearing capacity distribution map of soil shows that most of the University of Jember area at two meters depth has hard soil consistency and has a bearing capacity of around 83.9 - 110.9 kg/cm2. The results of comparative analysis of ArcGIS and CPT has a ratio of 0,758 for point 1 and 0,765 for point 2.
Penerapan Kepres Nomor 80 Tahun 2003 Dalam Proses Pemilihan Pemenang Tender Proyek Konstruksi di Sumatera Barat
Authors:   Universitas Bung Hatta, Peli Martalius , Ariani Vivi ,   Universitas Bung Hatta
Published: May 2021

Tender is a competition system for selecting contractors who will carry out development activities. The mistake of the tender committee in choosing a contractor will cause losses to the project owner. To avoid that mistake, the tender committee must know the capabilities and quality of the contractor, so an assessment of the capabilities of the contractor (construction service) is needed. This research was conducted only for the tender process of physical work and the questionnaire was given to 50 contractor companies in West Sumatra to determine the weight of seven criteria of the most important assessment process in tender tenders in accordance with Presidential Decree No. 80 Republic of Indonesia year 2003 (Keputusan Presiden No. 80 tahun 2003). 50 questionnaires are distributed with result 43 returned questionnaires showed that the assessment criteria for implementation time had the highest percentege of 19% followed by work methods and experts with a percentege of 17% and subsequently company capital with a percentege of 16%, and working capital received the fourth demand with a percentage of 11%, while the company's experience and ranks last is equipment with a percentege of 10%.
Mullah Sadra and the Problem of Specifics of Islamic Philosophy
Authors:   Chelyabinsk State University, Viktor Konstantinovich Shreiber
Published: May 2021

In this country, the name of Mullah Sadra is known to very few specialists, while con-temporary western scholars consider Sadra one of the classics of Muslim culture. These points define the structure and the content of this paper: what the word Islamic means in relation to philosophy and what caused such a high assessment of this person's creativity. In the first part, the author notes that any worldview reflects three attitudes of a person to the world, and on this basis then defines the difference in Islamic, Christian and Buddhist world outlooks. The second part is the description of the life path of ad-Din Shirazi from his discipleship, when his mentors were Mir Damad and Sheikh ul Islam Bahá'í, up to his return to Shiraz. Here the author dwells on the motives of Sadra's «hermitage» in Kohak. The specifics of Islamic philosophy is the sub-ject of the third section. The author considers the views of S. Meisami, M. Bilalov and O. Limen and concludes that the solution to this problem is not yet visible. In this regard, the heuristic po-tential of A. Smirnov’s «logical-semantic» theory suggesting to consider this specificity through the prism of relationship between the linguistic and conceptual (logical) pictures of the world, is discussed. The conclusion summarizes the author's reflections on the specifics of Arab-Muslim philosophy and Sadra's role in its development.
«Invented Traditions» of Indonesian Liberal Islam of the 2000s and the First Half of the 2010s
Authors:   Voronezh State University, Maksim Valerievich Kyrchanov
Published: May 2021

The author analyzes the problems of the ideology of liberal Islam as a political invented tradition of modern Indonesia. Liberal Islam became one of the marginal trends in recent Indo-nesian history. Its genesis became the result of the politicization of Islam as a form of ideologi-cal opposition in the period of the new order and the accelerated democratization that began in the late 1990s. Secularization gave an impetus to the emergence of liberal Islam. The artificial character of liberal Islam is actualized through its marginality. Ideologues of Indonesian Islam tried to popularize the invented political traditions of human rights, freedom, democracy, and tolerance. The political message of liberal Islam was not understood by society because liberal Muslims used Western cultural code. Therefore, liberal Indonesian Islam existed as an invented tradition that became a radical attempt to transplant Western values into post-colonial society.
Islamic Factor of Russian Statehood in the Preimperial Period
Authors:   Dagestan State University, Akhmedkhan Aminovich Saidov
Published: May 2021

The article examines the problems of the relationship between Islam and Orthodox Christianity in the Russian state in the pre-Soviet period, which, according to the author, acquires special relevance in connection with unfolding polemics in the contemporary Russian society, since historical memory influences the nature of these relationships. It analyzes various worldview and socio-political approaches and assessments of the nature of these relationships in the period under study. In this connection, the author reveals the positive socio-political and ge-ostrategic potential of Islam – the autochthonous religion of Russia. Based on the need to rely on the civilizational essence of Russia in the processes of state-building, the article identifies the negative factors that influenced the relationship between Islam and the Russian state in the past, which will now allow, without repeating mistakes, to create the necessary conditions for positive cooperation, to develop common features of the Eurasian identity, to coordinate the most im-portant elements of both political cultures on an ongoing basis. In the final part of the article, relying on the systemic and sociological approaches, the author substantiates the conclusion that, as a historically established Russian phenomenon, the Islamic factor was taken into account as one of the socio-cultural, politically significant elements both in the domestic and foreign policy of the Moscow state.
Ideological prerequisites for terrorist attacks by radical Islamists on objects in the United States (11.09.2001)
Authors:   Southern Federal University, Igor Prokopyevich Dobaev
Published: May 2021

Twenty years ago, terrorist attacks were carried out against a number of significant tar-gets in the United States. As a result, several thousand people died, and members of the radical Islamist group Al-Qaeda and personally its leader, Osama bin Laden, were declared terrorists, although there are other opinions about the organizers and customers of these attacks. In this article, the author examines the ideological prerequisites that some trends in Islam have accumu-lated for centuries, and that could have triggered the acts of terrorism by adherents of radical Islamism. Despite the fact that the ideologists of modern Islamism say that it is necessary to purify Islam from «sinful» layers and bring it in line with the «golden age» of this religion (610–661), they themselves literally parasitize on the ideological heritage of the founding fathers of radical views, starting from Ibn Hanbal, Ibn Taymiyyah, their students and followers. In this regard, it can be argued that modern Islamists, directly or indirectly borrowing the views and ideas of their predecessors (ideas about takfir, jihad, the judiciary, etc.), introduce other «sinful» innovations into the doctrinal provisions of Islam. This conclusion is vital for improving the effectiveness of counteracting the ideology and practice of radical Islamism, including in the Russian Federation.
La crisis ambiental en Medellín, una perspectiva desde la contabilidad.
Authors:   Universidad del Norte, Loboa Ortega Edward Eli , Sastoque Niyiret ,   Universidad del Norte, Mora Yeimer ,   Universidad Tecnológica de Bolívar
Published: May 2021

Durante el año 2016, se declaró alerta roja ambiental durante 40 días en Medellín, debido a las alarmantes cifras que arrojaba el SIATA, respecto a la calidad del aire del Valle de Aburrá; repitiéndose durante la misma temporada luego de varias alertas naranjas, haciendo evidente la crítica situación que enfrenta esta subregión en materia de planeación y administración ambiental. El presente artículo, reflexiona entorno a posibles factores que desde el punto de vista económico-administrativo podrían influir positivamente en la transformación de esta dinámica, al analizar el actual plan de desarrollo con relación al tema, teniendo como base contabilidad ambiental, que ha sido objeto de estudio de la ciencia contable y en la cual todavía falta mucho camino por recorrer, principalmente en el caso colombiano, pero que permiten comprender esta problemática desde un punto de vista necesario y poco frecuente en este tema.
Una revisión a los conceptos de comunicación estratégica y gestión pública en el marco de procesos organizacionales participativos
Authors:   Universidad Sergio Arboleda, Margarita Mejía Claudia , Navarro Díaz Luis Ricardo ,   Universidad del Norte
Published: May 2021

Este artículo analiza procesos de comunicación estratégica en la construcción de identidad, cultura y participación ciudadana, como pilares para asegurar la efectividad de la gestión pública en la búsqueda del cumplimiento de los objetivos y fines de las organizaciones. En este marco, se propone una revisión teórica que aborda el concepto de comunicación estratégica en relación con procesos de desarrollo de la gestión pública de las organizaciones. El impacto del estudio, no solo se encuentra en la posibilidad de ser asumido como referente teórico para la toma de decisiones por parte de los líderes de diversas organizaciones, sino en ofrecer reflexiones y procesos comunicati-vos pertinentes para realizar procesos de seguimiento y control por parte de los actores sociales pertenecientes a una organización
. El comercio electrónico como apoyo a la comercialización en empresas del sector refrigeración
Authors:   Universidad Simón Bolívar, Suárez López Diana , García Jiménez Rafael ,   Universidad Simón Bolívar
Published: May 2021

El presente trabajo tiene como objetivo proponer estrategias que ayuden a fortalecer la comercialización de los productos y servicios pertenecientes al sector de la refrigeración en la ciudad de Barranquilla, a través de herra-mientas tecnológicas ofrecidas por Internet, haciendo uso del marketing interactivo y de esta manera apoyar la toma de decisiones hacia la gerencia. Como primera medida se hizo un análisis interno para diagnosticar la situación actual de las empresas objeto de estudio, con respecto al uso que se les da a las herramientas Web que emplean o si no hacen uso de estas y bajo que estrategias están manejando la mercadotecnia dentro de la organización
Una mirada al estado de la aplicación de las normas internacionales de información financiera –NIIF– en Colombia
Authors:   Corporación Universitaria Americana, Hernández Caballero Francisco , Hernández Belaide Hernán ,   Corporación Universitaria Americana
Published: May 2021

Las Normas Internacionales de Contabilidad (NIC) y las Normas Internacionales de Información Financiera (NIIF), son estructuras normativas que tienen como propósito estandarizar los registros y reportes de información finan-ciera en la mayor parte de países del mundo. En la actualidad no existen estudios ni de carácter público ni priva-do que con suficiente rigurosidad y completitud den cuenta del proceso de adopción de estas normativas para Colombia. En este sentido este trabajo tuvo como propósito estudiar el estado de la aplicación de las NIIF para Colombia. Para esto se trabajó a través de una metodología con un enfoque descriptivo y de carácter documental. Las principales conclusiones que se derivan de este trabajo son que no existe la suficiente preparación y cono-cimiento de la mayoría de los profesionales involucrados en la responsabilidad de implementar estas normas; y además dado que son preceptos para estandarizar información a nivel internacional, está abierto el debate acerca de si es pertinente esta normativa para las pequeñas empresas que no comercian a nivel internacional y para las cuales esta implementación implicaría costos significativos.
Análisis de la gerencia de valor como instrumento impulsador de la sostenibilidad de las Pymes del sector colchonero en la ciudad de Medellín
Authors:   Universidad La Rioja, Torres Anillo Karen Margarita , Urrego Luis Eduardo ,   Universidad Simón Bolívar
Published: May 2021

Uno de los aspectos más importantes que se tocará en el transcurso de esta investigación será el de Gerencia de Valor, se quiere conocer cuáles son las estrategias implementadas por cada empresa seleccionada de la ciudad de Medellín, qué importancia le están dando a este factor y si verdaderamente sirve para la toma de decisiones y crecimiento de estas Pymes. Además, se quiere conocer cuál es el manejo financiero que los directivos de las pequeñas y medianas empresas específicamente del sector colchonero le están dando a este. El estudio se realizó a 20 empresarios con el fin de conocer cuáles son los procedimientos o estrategias que llevan a cabo en cuanto a la implementación de la Gerencia de Valor. Se llega a la conclusión de que las Pymes en Medellín tienen poco conocimiento de este modelo innovador y po-cas empresas son las que tienen en cuenta este factor en sus procesos de desarrollo empresarial, aunque algunos de estos empresarios son conscientes de la importancia de este elemento se reúsan a su implementación ya sea por desconocimiento o desconfianza.
Comportamiento de compra del consumidor de productos para mascotas en Latinoamérica
Authors:   Universidad Autónoma del Caribe, Coll Blanco Cenaida , De La Rosa Blanco Sandra ,   Universidad Simón Bolívar
Published: May 2021

El presente artículo de revisión tuvo por objetivo indagar sobre el comportamiento del consumidor de productos para mascotas en Latinoamérica, para ello, se llevó a cabo una revisión de corte descriptivo y compilativo. En efecto, se compilaron referentes bibliográficos de bases de datos científicas, que no superaran los diez años de publicación en idioma español e inglés. Los principales resultados arrojaron que el tipo de mascota preferido son los perros con cerca de un 70% y los gatos con un 23%, también se evidencio que dichos animales son considerados un miembro más de la familia, por lo cual se estipula un presupuesto mensual destinado a satisfacer sus necesidades de bienestar y cuidado. Se estima que al finalizar el 2018, el mercado de las mascotas en la región de Sudamérica, puede llegar a alcanzar un crecimiento del 4.2% en la tenencia de mascotas, y hasta del 12,5% anual en consumo de bienes y servicios para mascotas. A nivel general, los productos que registran mayores ventas, en este sector, son los relacionados con la alimentación, en el 2016 la producción mundial de alimento balanceado para perros superó por primera vez en la historia la barrera de los 1.000 millones de toneladas métricas
Análisis de la calidad de servicio del sector turístico en ciudad fronteriza
Authors:   Universidad Autónoma de Baja California, Ruiz Andrade José Gabriel , Martínez Moreno Omaira Cecilia ,   Universidad Autónoma de Baja California, Verján Quiñones Ricardo ,   Universidad Autónoma de Baja California
Published: May 2021

El presente artículo se ha enfocado en medir la percepción de la calidad del servicio y satisfacción de los clientes del sector hotelero en la ciudad fronteriza de Tijuana, ubicada en la zona noroeste de México.Para la recolección de datos, se aplicó una encuesta compuesta por preguntas de selección múltiple, a una muestra de huéspedes que se calculó mediante un muestreo probabilístico intencionado que determinó la cantidad a encuestar. Se definió como perfil del encuestado, huéspedes que se encontraran realizando su registro de salida (check out) dentro de las instalaciones del hotel.Los resultados reflejan la necesidad de implementar estrategias que coadyuven a elevar la calidad de servicio que reciben los huéspedes de los hoteles sujetos de análisis
Editorial
Authors:   Corporación Universitaria Americana, Robledo Fernandez Juan Carlos
Published: May 2021

Cuando una sociedad se mueve más rápido que su misma conciencia colectiva, ¿Cuál es el conocimiento que necesitamos? La respuesta puede tener diversas posturas, aproximaciones teóricas y epistemológi-cas. Sin embargo, cuando la pregunta se hace en el contexto del mundo empresarial, emerge una acotación o asíntota que implica el replanteamiento de modelos actuales tanto de gerencia como de organizaciones.
Estructuras organizacionales: nuevas tendencias
Authors:   Corporación Politécnico Costa Atlántica, Porto Solano Andrés , Angarita Álvarez Laura ,   Universidad del Norte
Published: May 2021

Este artículo tiene por objetivo analizar, comparar criterios respecto a distintos tipos de estructuras organizacionales que adoptan las diferentes empresas u organizaciones. Adicional a lo anterior se de-marcó las nuevas tendencias en la adopción y diseño de las estructuras organizacionales, explicando además su origen y concepción. Se logró constatar que las tendencias, las estructuras organizacionales de las empresas difieren según el tipo de organización, destacándose en las manufactureras la estructura en red, y en las prestadoras de servicios las estructuras adhocrática, hipertrébol, hipertexto y circular.
Tendencias de la Responsabilidad Social Universitaria (RSU ) de las Institu-ciones de Educación Superior (IES ) en la ciudad de Medellín-Colomb
Authors:   Tecnológico de Antioquia, Ceballos Betancur Wilfer  Arley
Published: May 2021

La organización de redes u otros sistemas de acción colectiva en torno a la Responsabilidad Social Uni-versitaria (RSU) en la ciudad de Medellín se han presentado de forma itinerante en la última década, pero su presencia en la gestión de algunas Instituciones de Educación Superior (IES) ha sido determi-nante, esto se evidencia en el cumplimiento de políticas gubernamentales con afinidad a la RSU, como es la rendición anual de cuentas realizada por las IES públicas. De igual forma, se observa en que la RSU directa o indirectamente es tema de trabajo en las IES, mediada por las exigencias de la Política de Ase-guramiento de la Calidad del Ministerio de Educación Nacional (MEN), que ha reforzado los requisitos de aprobación de instituciones, programas y procesos en una creciente dinámica que Latinoamérica conoce ya de forma determinante: los requisitos y acreditaciones de calidad. El presente texto que compendia elementos de un proyecto de investigación financiado por el Tecnológico de Antioquia I.U. en los años 2016 y 2017, busca desde una propuesta hermenéutica, y haciendo uso de fuentes primarias y secundarias de información, develar las tendencias que presenta la RSU desarrollada por parte de las IES en la ciudad de Medellín (Colombia) en la última década, desde los hechos relevantes acontecidos, así como desde las tendencias que se hicieron evidentes a partir de sus esfuerzos
Integration of Digital Tools Into Community Mental Health Care Settings That Serve Young People: Focus Group Study
Authors: Knapp Ashley A , Cohen Katherine , Nicholas Jennifer , Mohr David C , Carlo Andrew D , Skerl Joshua J , Lattie Emily G
Published: May 2021

Background

Digital mental health tools have substantial potential to be easily integrated into people’s lives and fundamentally impact public health. Such tools can extend the reach and maximize the impact of mental health interventions. Before implementing digital tools in new settings, it is critical to understand what is important to organizations and individuals who will implement and use these tools. Given that young people are highly familiar with technology and many mental health concerns emerge in childhood and adolescence, it is especially crucial to understand how digital tools can be integrated into settings that serve young people.

Objective

This study aims to learn about considerations and perspectives of community behavioral health care providers on incorporating digital tools into their clinical care for children and adolescents.

Methods

Data were analyzed from 5 focus groups conducted with clinicians (n=37) who work with young people at a large community service organization in the United States. This organization provides care to more than 27,000 people annually, most of whom are of low socioeconomic status. The transcripts were coded using thematic analysis.

Results

Clinicians first provided insight into the digital tools they were currently using in their treatment sessions with young people, such as web-based videos and mood-tracking apps. They explained that their main goals in using these tools were to help young people build skills, facilitate learning, and monitor symptoms. Benefits were expressed, such as engagement of adolescents in treatment, along with potential challenges (eg, accessibility and limited content) and developmental considerations (eg, digital devices getting taken away as punishment). Clinicians discussed their desire for a centralized digital platform that securely connects the clinician, young person, and caregivers. Finally, they offered several considerations for integrating digital tools into mental health care, such as setting up expectations with clients and the importance of human support.

Conclusions

Young people have unique considerations related to complex accessibility patterns and technology expectations that may not be observed when adults are the intended users of mental health technologies. Therefore, these findings provide critical insights to inform the development of future tools, specifically regarding connectivity, conditional restraints (eg, devices taken away as punishment and school restrictions), expectations of users from different generations, and the blended nature in which digital tools can support young people.
Mobile Game Design Guide to Improve Gaming Experience for the Middle-Aged and Older Adult Population: User-Centered Design Approach (Preprint)
Authors: Lee Seyeon , Oh Hyunyoung , Shi Chung-Kon , Doh Young Yim
Published: May 2021

BACKGROUND

The number of older adult gamers who play mobile games is growing worldwide. Earlier studies have reported that digital games provide cognitive, physical, and socioemotional benefits for older adults. However, current mobile games that understand older adults’ gameplay experience and reflect their needs are very scarce. Furthermore, studies that have analyzed older adults’ game experience in a holistic manner are rare.

OBJECTIVE

The purpose of this study was to suggest mobile game design guidelines for adults older than 50 years from a holistic gaming experience perspective. Adopting a human-centric approach, this study analyzes middle-aged and older adults’ gameplay experience and suggests practical design guides to increase accessibility and satisfaction.

METHODS

We organized a living laboratory project called the “Intergenerational Play Workshop.” In this workshop, 40 middle-aged and older adults (mean age 66.75 years, age range 50-85 years) played commercial mobile games of various genres with young adult partners for 1 month (8 sessions). Using a convergent parallel mixed-method design, we conducted a qualitative analysis of dialogue, game diaries, and behavioral observations during the workshop and a quantitative analysis of the satisfaction level of the game elements for the mobile games that they played.

RESULTS

This project was active from April 2019 to December 2021, and the data were collected at the workshops from July 1 to August 28, 2019. Based on the identified themes of positive and negative experiences from the qualitative data, we proposed 45 design guides under 3 categories: (1) cognitive and physical elements, (2) psychological and socioemotional elements, and (3) consumption contextual elements. Our empirical research could reaffirm the proposals from previous studies and provide new guidelines for improving the game design. In addition, we demonstrate how existing commercial games can be evaluated quantitatively by using the satisfaction level of each game’s elements and overall satisfaction level.

CONCLUSIONS

The final guidelines were presented to game designers to easily find related information and enhance the overall understanding of the game experience of middle-aged and older adults.
Virtual Reality Simulation Training for Cardiopulmonary Resuscitation After Cardiac Surgery: Face and Content Validity Study (Preprint)
Authors: Sadeghi Amir H , Peek Jette J , Max Samuel A , Smit Liselot L , Martina Bryan G , Rosalia Rodney A , Bakhuis Wouter , Bogers Ad JJC , Mahtab Edris AF
Published: May 2021

BACKGROUND

Cardiac arrest after cardiac surgery commonly has a reversible cause, where emergency resternotomy is often required for treatment, as recommended by international guidelines. We have developed a virtual reality (VR) simulation for training of cardiopulmonary resuscitation (CPR) and emergency resternotomy procedures after cardiac surgery, the Cardiopulmonary Resuscitation Virtual Reality Simulator (CPVR-sim). Two fictive clinical scenarios were used: one case of pulseless electrical activity (PEA) and a combined case of PEA and ventricular fibrillation. In this prospective study, we researched the face validity and content validity of the CPVR-sim.

OBJECTIVE

We designed a prospective study to assess the feasibility and to establish the face and content validity of two clinical scenarios (shockable and nonshockable cardiac arrest) of the CPVR-sim partly divided into a group of novices and experts in performing CPR and emergency resternotomies in patients after cardiac surgery.

METHODS

Clinicians (staff cardiothoracic surgeons, physicians, surgical residents, nurse practitioners, and medical students) participated in this study and performed two different scenarios, either PEA or combined PEA and ventricular fibrillation. All participants (N=41) performed a simulation and completed the questionnaire rating the simulator’s usefulness, satisfaction, ease of use, effectiveness, and immersiveness to assess face validity and content validity.

RESULTS

Responses toward face validity and content validity were predominantly positive in both groups. Most participants in the PEA scenario (n=26, 87%) felt actively involved in the simulation, and 23 (77%) participants felt in charge of the situation. The participants thought it was easy to learn how to interact with the software (n=24, 80%) and thought that the software responded adequately (n=21, 70%). All 15 (100%) expert participants preferred VR training as an addition to conventional training. Moreover, 13 (87%) of the expert participants would recommend VR training to other colleagues, and 14 (93%) of the expert participants thought the CPVR-sim was a useful method to train for infrequent post–cardiac surgery emergencies requiring CPR. Additionally, 10 (91%) of the participants thought it was easy to move in the VR environment, and that the CPVR-sim responded adequately in this scenario.

CONCLUSIONS

We developed a proof-of-concept VR simulation for CPR training with two scenarios of a patient after cardiac surgery, which participants found was immersive and useful. By proving the face validity and content validity of the CPVR-sim, we present the first step toward a cardiothoracic surgery VR training platform.
Evaluasi Luaran Klinis Terapi Antibiotika pada Pasien Anak Rawat Inap Dengan Infeksi Saluran Kemih di RSUP Dr. Sardjito Yogyakarta
Authors: Adhitama Widya , Puspitasari Ika , Laksanawati Ida Safitri
Published: May 2021

Infeksi Saluran Kemih (ISK) merupakan penyakit infeksi yang sering terjadi pada anak selain infeksi saluran nafas atas dan diare di negara berkembang. Salah satu terapi yang diberikan adalah antibiotik, pemilihan antibiotik harus didasarkan pola resistensi bakteri lokal. Tujuan penelitian ini untuk menilai hubungan rasionalitas antibiotik empiris terhadap luaran klinis pasien anak rawat inap dengan ISK di Rumah Sakit dr. Sardjito Yogyakarta. Penelitian ini merupakan penelitian  observasional menggunakan rancangan deskriptif-analitik dengan desain cohort retrospektif. Subyek penelitian adalah pasien anak rawat inap dengan ISK di Rumah Sakit dr. Sardjito Yogyakarta periode 1 Januari 2016 – 31 Desember 2018. Jumlah pasien yang memenuhi kriteria inklusi dan eksklusi sebanyak 63 pasien dengan 70 regimen antibiotik. Rasionalitas penggunaan antibiotik empiris dievaluasi menggunakan metode Gyssens. Hasil dari penelitian ini menunjukkan antibiotik empiris yang rasional yaitu sebesar 84,3% (59 regimen), dan yang tidak rasional sebesar 15,7% (11 regimen). Pada penggunaan antibiotik yang rasional dan memberikan luaran klinis membaik sebesar 82,9%, dan dianalisis dengan uji Fisher menunjukkan adanya hubungan yang signifikan antara rasionalitas antibiotik empiris terhadap luaran klinis pasien anak ISK dengan nilai p=0,011. Gambaran pola bakteri pada pasien ISK anak yaitu bakteri yang menginfeksi terbesar dari bakteri gram negatif (81,97%) dan bakteri gram positif sebesar 18,03%.
Luaran Klinis dan Analisis Biaya Konversi dari Antibiotik Intravena Ke Oral pada Pasien Community Acquired Pneumonia di Rumah Sakit Akademik Universitas Gadjah Mada
Authors: Ngani Altaufik , Nuryastuti Titik , Andayani Tri Murti
Published: May 2021

Beberapa studi mengusulkan konversi terapi antibiotik intravena ke oral untuk menurunkan lama rawat inap dan biaya dalam pengobatan Community Acquired Pneumonia (CAP) yang masih menjadi masalah di Indonesia. Penelitian ini bertujuan untuk mengetahui gambaran tentang praktik konversi antibiotik intravena ke oral pada pasien CAP serta menganalisis biaya dari terapi tersebut. Penelitian ini dilakukan dengan rancangan cross sectional terhadap pasien CAP di RSA UGM. Data yang diambil berupa rekam medik pasien rawat inap periode Januari 2017-Desember 2019 yang selanjutnya dibagi ke dalam dua kelompok yakni kelompok konversi ≤ hari ke-3 dan kelompok konversi > hari ke-3. Hasil penelitian menunjukan bahwa switch therapy merupakan jenis konversi paling banyak digunakan (60,6%). Merujuk pada luaran klinis, terdapat perbedaan yang signifikan (p<0,05) antara kelompok antibiotik intravena konversi ≤ hari ke-3 dan kelompok antibiotik antibiotik intravena konversi >hari ke 3 terhadap LOS (4,21±0,99 vs 5,65±1,40). Hal yang sama terjadi pada analisis biaya, yang juga menunjukan perbedaan siginifikan (p<0,05) antara kelompok antibiotik intravena konversi ≤ hari ke-3 dan kelompok antibiotik intravena konversi >hari ke-3 terhadap biaya antibiotik dengan biaya total masing-masing Rp.126.022,33 vs Rp.274.283,82 dan Rp.2.610.283,66 vs Rp.3.696.681,06. Konversi antibiotik intravena ke oral ≤ hari ke-3 menghasilkan lama rawat inap yang lebih rendah dan penghematan biaya pengobatan.
The Influence of Cause-Related Marketing on Millennials’ Purchase Intentions: Evidence of CSR from an Emerging Economy
Authors: Shetty Swapna J , Chaudhuri Molly Sanjay , Shetty Ankitha
Published: May 2021

Corporate social responsibility (CSR) has been implemented through sponsorships, philanthropy, and cause-related marketing (CRM), amongst which CRM has aroused the interest of many academicians and stakeholders. The study aims to examine the antecedents of cause-related marketing while considering attitude as a mediator to test its relationship with the purchase intention. The snowball sampling technique for data collection was administered to Indian millennial consumers from the regions of Karnataka and Kerala. A total of 313 valid cases were selected for the analysis, which employed partial least squares (PLS) based on structural equation modeling (SEM). The findings have shown that a positive relationship exists between cause participation and purchase intention. Further, product/cause congruence & consumer/cause identification had a positive impact on attitude, while attitude, in turn, showed a favorable association with the purchase intention. This study disclosed the relative importance of the compatibility between the social causes supported by the company with its engaged business while adopting CRM campaigns, and highlighted the need for the involvement of consumers in the CRM programs for their effectiveness.