bluuebunny/crossref_metadata_2025 huggingface dataset:
HRCT imaging of acquired cholesteatoma: a pictorial review
Authors: Gulati Malvika , Gupta Swati , Prakash Anjali , Garg Anju , Dixit Rashmi
Published: October 2019

Chronically discharging ear is a common cause of morbidity in developing countries, and it is also associated with intratemporal and intracranial complications. The surgeon is often able to detect the disease. However, cholesteatoma in the “hidden areas” like anterior epitympanic recess and sinus tympani can be missed. Facial nerve involvement and cholesteatomatous erosion of the bony labyrinth are dreaded complications, the extent of which cannot be assessed completely on clinical examination. Adding to the complexity are the various variations in anatomy like high riding jugular bulb and aberrant internal carotid artery which could lead to catastrophic complications during surgery if left undetected preoperatively. HRCT temporal bone is useful to detect the extent of the disease, various complications, and guide the surgeon for pre-operative planning. In this review, we go through the various HRCT imaging features of acquired cholesteatoma, a reporting template, and a few words about imaging of the post-operative ear.
IcarisideII facilitates the differentiation of ADSCs to SCs via let-7i/STAT3 axis to preserve erectile function
Authors: Ge Pingyu , Guo Yinxue , Shen Jun
Published: October 2019

Background

IcarisideII (ICAII) could promote the differentiation of adipose tissue-derived stem cells (ADSCs) to Schwann cells (SCs), leading to improvement of erectile function (EF) and providing a realistic therapeutic option for the treatment of erectile dysfunction (ED). However, the underlying molecular mechanisms of ADSCs and ICAII in this process remain largely unclear.

Methods

ADSCs were treated with different concentrations of ICAII. Cell proliferation was determined by MTT assay. qRT-PCR and western blot were performed to detect expressions of SCs markers, signal transducer and activator of transcription-3 (STAT3), and microRNA-let-7i (let-7i). Luciferase reporter assay was conducted to verify the regulatory relationship between let-7i and STAT3. The detection of intracavernosal pressure (ICP) and the ratio of ICP/mean arterial pressure (MAP) were used to evaluate the EF in bilateral cavernous nerve injury (BCNI) rat models.

Results

ICAII promoted cell proliferation of ADSCs in a dose-dependent manner. The mRNA and protein levels of SCs markers were increased by ICAII treatment in a dose-dependent manner in ADSCs. Moreover, let-7i was significantly decreased in ICAII-treated ADSCs and upregulation of let-7i attenuated ICAII-induced promotion of SCs markers. In addition, STAT3 was a direct target of let-7i and upregulated in ICAII-treated ADSCs. Interestingly, overexpression of STAT3 abated the let-7i-mediated inhibition effect on differentiation of ADSCs to SCs and rescued the ICAII-mediated promotion effect on it. Besides, combination treatment of ADSCs and ICAII preserved the EF of BCNI rat models, which was undermined by let-7i overexpression.

Conclusion

ICAII was effective for preserving EF by promoting the differentiation of ADSCs to SCs via modulating let-7i/STAT3 pathway.
Online module login data as a proxy measure of student engagement: the case of myUnisa, MoyaMA, Flipgrid, and Gephi at an ODeL institution in South Africa
Authors: Chaka Chaka , Nkhobo Tlatso
Published: October 2019

The current study employed online module login data harvested from three tools, myUnisa, MoyaMA and Flipgrid to determine how such data served as a proxy measure of student engagement. The first tool is a legacy learning management system (LMS) utilised for online learning at the University of South Africa (UNISA), while the other two tools are a mobile messaging application and an educational video discussion platform, respectively. In this regard, the study set out to investigate the manner in which module login data of undergraduate students (n = 3475 & n = 2954) and a cohort of Mathew Goniwe students (n = 27) enrolled for a second-level module, ENG2601, as extracted from myUnisa, MoyaMA, and Flipgrid served as a proxy measure of student engagement. Collectively, these students were registered for this second-level module at UNISA at the time the study was conducted. The online login data comprised myUnisa module login file access frequencies. In addition, the online login data consisted of the frequencies of instant messages (IMs) posted on MoyaMA by both the facilitator and Mathew Goniwe students, and video clips posted on and video clip view frequencies captured by Flipgrid in respect of the afore-cited module. One finding of this study is that student engagement as measured by login file access frequencies was disproportionally skewed toward one module file relative to other module files. The other finding of this study is that the overall module file access metrics of the Mathew Goniwe group were disproportionally concentrated in a sub-cohort of highly active users (HAU).
GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126
Authors: Mahamud Md. Riaj , Geng Xin , Ho Yen-Chun , Cha Boksik , Kim Yuenhee , Ma Jing , Chen Lijuan , Myers Greggory , Camper Sally , Mustacich Debbie , Witte Marlys , Choi Dongwon , Hong Young-Kwon , Chen Hong , Varshney Gaurav , Engel James Douglas , Wang Shusheng , Kim Tae-Hoon , Lim Kim-Chew , Srinivasan R. Sathish
Published: October 2019

Mutations in the transcription factor GATA2 cause lymphedema. GATA2 is necessary for the development of lymphatic valves (LVs) and lymphovenous valves (LVVs), and for the patterning of lymphatic vessels. Here, we report that GATA2 is not necessary for valvular endothelial cell (VEC) differentiation. Instead, GATA2 is required for VEC maintenance and morphogenesis. GATA2 is also necessary for the expression of cell junction molecules VE-Cadherin and Claudin5 in lymphatic vessels. We identified miR-126 as a target of GATA2, and miR-126−/- embryos recapitulate the phenotypes of mice lacking GATA2. Primary human lymphatic endothelial cells (HLECs) lacking GATA2 (GATA2ΔHLEC) have altered expression of Claudin5 and VE-Cadherin, and blocking miR-126 activity in HLECs phenocopies these changes in expression. Importantly, overexpression of miR-126 in GATA2ΔHLEC significantly rescues the cell junction defects. Thus, our work defines a new mechanism of GATA2 and uncovers miR-126 as a novel regulator of mammalian lymphatic vascular development.
The Fabrication of Rigid Crosslinker-Decorated Gold Nanoparticle Array Film for Catalyzing CO2 Cycloaddition
Authors: Li Yunong , Guo Yaohui , Xia Mingjian , Shao Lei , Zhou Yuan , Bai Xiaojue , Li Linlin , Zhou Jun , Chen Dan , Zhang Xuemin , Wang Tieqiang , Zhang Liying , Fu Yu
Published: October 2019

In order to precisely design the active sites in two-dimensional (2D) gold-based catalysts, we have developed a convenient and versatile plasma-assisted droplet evaporation-rigid crosslinking method for the fabrication of gold nanoparticle (Au NP) array film. Four kinds of Au NP arrays have been decorated respectively with rigid sulfurated crosslinkers i.e. thieno[3,2-b]thiophene, 2,2′-bithiophene, 1,4-benzenedithiol and 4,4′-thiodibenzenethiol, and the density of crosslinkers can be adjusted under plasma treatment. Particularly, the utilization of 4,4′-thiodibenzenethiol gave uniform particle sizes to form a periodical 2D structure, which provides multiple exposed active sites of gold nanoparticles rather than enwinding by the alkyl chains. Meanwhile, the weaker electron-donating effect and steric hindrance of rigid groups in the crosslinkers could also enhance the catalytic activity. In addition, the Au NP array film can be transferred from the glass substrate and further composited with polymers and metal organic framework (MOF) into self-standing composite membrane. Therefore, this rigid crosslinked array film can serve as an environmentally friendly catalyst for CO2 cycloaddition under atmospheric CO2 pressure, which offers a novel application of Au NPs array film, and opens up a new way for the design and fabrication of 2D hybrid materials.
Transient up-regulation of miR-155-3p by lipopolysaccharide in primary human monocyte-derived macrophages results in RISC incorporation but does not alter TNF expression
Authors: Simmonds Rachel E.
Published: October 2019

Background: The innate immune response is a tightly regulated process that reacts rapidly in response to pathogen-associated molecular patterns (PAMPs) such as lipopolysaccharide (LPS). Evidence is accumulating that microRNAs contribute to this, although few studies have examined the early events that constitute the “primary” response.

Methods: LPS-dependent changes to miRNA expression were studied in primary human monocyte-derived macrophages (1°MDMs). An unbiased screen by microarray was validated by qPCR and a method for the absolute quantitation of miRNAs was also developed, utilising 5’ phosphorylated RNA oligonucleotide templates. RNA immunoprecipitation was performed to explore incorporation of miRNAs into the RNA-induced silencing complex (RISC). The effect of miRNA functional inhibition on TNF expression (mRNA and secretion) was investigated.

Results: Of the 197 miRNAs expressed in 1°MDMs, only five were induced >1.5-fold. The most strongly induced was miR-155-3p, the partner strand to miR-155-5p, which are both derived from the MIR155HG/BIC gene (pri-miR-155). The abundance of miR-155-3p was induced transiently ~250-fold at 2-4hrs and then returned towards baseline, mirroring pri-miR-155. Other PAMPs, IL-1β, and TNF caused similar responses. IL-10, NF-κB, and JNK inhibition reduced these responses, unlike cytokine-suppressing mycolactone. Absolute quantitation revealed that miRNA abundance varies widely from donor-to-donor, and showed that miR-155-3p abundance is substantially less than miR-155-5p in unstimulated cells. However, at its peak there were 446-1,113 copies/cell, and miR-155-3p was incorporated into the RISC with an efficiency similar to miR-16-5p and miR-155-5p. Inhibition of neither miRNA affected TNF secretion after 2hrs in 1°MDMs, but technical challenges here are noted.

Conclusions: Dynamic regulation of miRNAs during the primary response is rare, with the exception of miR-155-3p. Further work is required to establish whether its low abundance, even at the transient peak, is sufficient for biological activity and to determine whether there are specific mechanisms determining its biogenesis from miR-155 precursors
A crença no Profeta: uma abordagem crítica das memórias de Samuel Wainer
Authors: Antonio Mariana Dias , Guimarães Marcella Lopes
Published: October 2019

Minha Razão de Viver, autobiografia do jornalista Samuel Wainer, é um livro comumente utilizado em cursos e pesquisas acadêmicas que abordam a imprensa ou a política do Brasil contemporâneo, às vezes levando ao uso acrítico de dados e eventos pontuais presentes em sua narrativa. Buscamos fornecer uma visão geral crítica a partir de alguns casos pontuais, confrontando o relato autobiográfico e outras fontes, documentais e/ou bibliográficas. Embora os casos aqui trazidos e confrontados não esgotem as diversas possibilidades contidas em Minha Razão de Viver, o presente trabalho demonstra a necessidade constante de validação dos conteúdos trazidos nas histórias de vida.
Alícia Vega: Taller de Cine para Niños nos labirintos do tempo
Authors: De Oliveira Azeredo Verônica Pacheco , Andrade Dias Marília Sousa
Published: October 2019

Este artigo tem o objetivo apresentar parte de uma investigação acerca da teoria pedagógica de Alícia Vega, intelectual latino-americana com atuação importante na criação de projetos de formação estética audivisual de crianças pobres do Chile. Foram realizadas entrevistas narrativas concedidas na Galeria Macchina, Pontifícia Universidade Católica do Chile, em Santiago por ocasião da exposição “Taller de Cine para Niños” nos meses de abril e maio de 2018, em homenagem aos 30 anos desse projeto voltado para a educação e cinema. A pesquisa, realizada pela perspectiva historiográfica da História das Mulheres, assenta-se no campo da História Oral, com foco nos Relatos Orais.
Imaginário da mobilidade na obra Rakushisha, de Adriana Lisboa: entre o fluxo e a fixidez
Authors: Braga Cláudio Roberto Vieira , Cardoso Bruno
Published: October 2019

O artigo tem por objetivo analisar o romance Rakushisha, da escritora brasileira Adriana Lisboa, publicado em 2007. O recorte analítico focaliza ações e imagens de mobilidade presentes na obra, de forma que o curso da investigação evidencia como tais ações e imagens, não raro, revestem-se de profundo significado existencial, culminando com seus personagens protagonistas em situações de descoberta interior ou de “insights epifânicos sobre o eu”, conforme Thompson (2011). A partir disso, com base no próprio Carl Thompson (2011), e também em Maria Zilda Ferreira Cury (2012) e Tim Cresswell (2006), o artigo evidencia como a construção discursiva de um imaginário da mobilidade projeta-se em Rakushisha por meio de uma negociação entre as instâncias metafísicas do fluxo e da fixidez. Essa negociação se revela na instabilidade identitária das personagens protagonistas representadas, na construção de um discurso pós-nacional que vai além de essencialismos e estereótipos nacionais e, por fim, nas próprias reflexões sobre o ato de escrita, construídas na chave metafórica da viagem, no deslocamento incessante de signos.
Negotiation of care practices by mothers with disabilities in Russia
Authors: Battalova Alfiya
Published: October 2019

Drawing on qualitative interviews that focus on the experiences of mothers with disabilities in Russia, this article explores the role of family support in shaping care practices and in challenging traditional notions of caregiving and care receiving. By delving into the micro-level structure of care, this research demonstrates the nuances of negotiating care in the context of mothering with a disability and uncovers ways of claiming citizenship. The analysis reveals that care is manifested through a multilayered practice that is contingent on multiple actors and social configurations, as well as emotional labour.
The new method of Exponential Random Graph Modelling to analyse interactions in participatory processes of place branding
Authors: Stevens Vidar
Published: October 2019

By introducing the statistical network method of Exponential Random Graph Modelling (ERGM) we adhere to the call of Lucarelli and Brorström (2013) in The Marketing Review to think of new ways to analyse and make inferences about participatory processes of place branding.
The ERGM is more suited for studying the interactive dynamics in participatory processes of place branding than traditional methods like case study research or regression analysis. ERGM is a relatively new methodology. Only a few scholars in the neurosciences, international relations, and
political sciences have worked with the inferential social network method. We show that the new ERGM methodology helps to gain more insights into the social processes and tie-formation mechanisms which generate emergent interaction patterns in participatory processes of place branding. Hence,
this article brings a novel methodology to the area of place branding.
Cardiac and Stress Biomarkers and Chronic Kidney Disease Progression: The CRIC Study
Authors: Bansal Nisha , Zelnick Leila , Shlipak Michael G , Anderson Amanda , Christenson Robert , Deo Rajat , deFilippi Christopher , Feldman Harold , Lash James , He Jiang , Kusek John , Ky Bonnie , Seliger Stephen , Soliman Elsayed Z , Go Alan S
Published: October 2019

BACKGROUND

Increases in cardiac and stress biomarkers may be associated with loss of kidney function through shared mechanisms involving cardiac and kidney injury. We evaluated the associations of cardiac and stress biomarkers [N-terminal pro-B-type natriuretic peptide (NT-proBNP), high-sensitivity troponin T (hsTnT), growth differentiation factor 15 (GDF-15), soluble ST-2 (sST-2)] with progression of chronic kidney disease (CKD).

METHODS

We included 3664 participants with CKD from the Chronic Renal Insufficiency Cohort study. All biomarkers were measured at entry. The primary outcome was CKD progression, defined as progression to end-stage renal disease (ESRD) or 50% decline in estimated glomerular filtration rate (eGFR). Cox models tested the association of each biomarker with CKD progression, adjusting for demographics, site, diabetes, cardiovascular disease, eGFR, urine proteinuria, blood pressure, body mass index, cholesterol, medication use, and mineral metabolism.

RESULTS

There were 1221 participants who had CKD progression over a median (interquartile range) follow-up of 5.8 (2.4–8.6) years. GDF-15, but not sST2, was significantly associated with an increased risk of CKD progression [hazard ratios (HRs) are per SD increase in log-transformed biomarker]: GDF-15 (HR, 1.50; 95% CI, 1.35–1.67) and sST2 (HR, 1.07; 95% CI, 0.99–1.14). NT-proBNP and hsTnT were also associated with increased risk of CKD progression, but weaker than GDF-15: NT-proBNP (HR, 1.24; 95% CI, 1.13–1.36) and hsTnT (HR, 1.11; 95% CI, 1.01–1.22).

CONCLUSIONS

Increases in GDF-15, NT-proBNP, and hsTnT are associated with greater risk for CKD progression. These biomarkers may inform mechanisms underlying kidney injury.
Ethnicity, Politics, and the Rhetoric of Genocide at Eldoret
Authors: Harroff Lindsay
Published: October 2019

In this essay, I offer a reception study of the varied responses to and interpretations of a burning church in the town of Eldoret following the 2007 Kenya presidential election. Specifically, I study responses from the U.S. and British media, U.S. officials, and Kenyan politicians. My analysis illuminates how different uses of the term “genocide” mobilize particular sensibilities about the relation between ethnicity and politics and demonstrates how the label of genocide constrains interpretations of violence. In the media and discourse of U.S. politicians, the identification or denial of genocide was made by setting ethnicity and politics as opposing explanatory factors of the violence. Discourses in Kenya, however, demonstrate that understanding the violence required understanding the intersection and permeability of these same categories. This analysis has important implications for understanding how conflicts are and are not named genocide. It demonstrates the importance of attending to the nuanced rhetoric of genocide and calls our attention to the contingent relationships among ethnicity, politics, and genocide.
Comparison of two methods for the assessment of the levels of autoantibodies to thyroid tissue antigens
Authors: Rudenko I. Ya. , Skorodok Yu. L. , Klimovich V. B.
Published: October 2019

The levels of autoantibodies to total extract of the thyroid were assessed using passive hemagglutination test and of antibodies to thyroglobulin (TG) and thyrocyte microsomal fraction (TMF) by indirect solid-phase enzyme immunoassay in 62 adolescent girls with diffuse enlargement of the thyroid and autoimmune thyroiditis. The efficacies of the two methods were compared. Autoantibodies to thyroid tissue antigens were reliably better detected by enzyme immunoassay. The mean levels of autoantibodies to TG and TMF measured by enzyme immunoassay were reliably increased in patients with autoimmune thyroiditis, whereas in the group of adolescent girls with diffuse enlargement of the thyroid they did not differ from the norm.
Diagnosis of thyroid cancer
Authors: Oleinik V. A. , Bezverkhaya T. P. , Epstein Ye. V. , Bozhok Yu. M.
Published: October 2019

It is believed that thyroid cancer is quite rare, accounting for less than 1% of the total number of malignant tumors in the population in all countries of the world. However, studies in recent years have revealed a significant increase in the incidence of thyroid cancer and its pronounced geographical differences. Therefore, while in Japan it is 0.5 per 100,000 of the population for men and 1.9-3.0 per 100,000 of the population for women, in Norway it is 2.0 and 5.8 per 100,000 of the population, respectively. In addition, there was information about the high frequency of the latent thyroid cancer. In Japan, in particular, latent thyroid cancer is found in 5.6–35.6% of autopsies included in the statistics. We are talking about random finds in people who died from non-endocrine diseases. The clinical significance of latent cancer is still unknown. This is evidence that malignant tumors of the thyroid gland are not a rare disease and are often not diagnosed during the patient’s life.
Role of training programs in the treatment of patients with type II diabetes mellitus
Authors: Surkova Ye. V. , Antsiferov M. B.
Published: October 2019

According to the Ministry of Health of the Russian Federation, the number of patients with non-insulin-dependent diabetes mellitus (NIDDM) in Russia is currently 1.6 million. Providing effective treatment for NIDDM is a significant problem for domestic health in terms of both quantitative indicators and the quality of medical care. Successful therapy of this disease is impossible without changing the patient’s lifestyle. The treatment process affects such essential aspects of lifestyle as nutrition, physical activity, control of body weight, and continues throughout life. In this regard, the effectiveness of the traditional therapeutic approach to NIDDM is not high enough and, according to experts, the motivation to control and treat diabetes cannot be achieved without training.
Growth hormone releasing factor and assessment of growth hormone reserve in children
Authors: Tyulpakov A. N. , Bulatov A. A. , Peterkova V. A. , Volevodz N. N. , Yelizarova G. P.
Published: October 2019

Pituitary somatotrophic reserve was assessed in children with growth delay using clofelin and growth hormone releasing factor (GH-RH). Thirty-four children hospitalized with suspected insufficiency of growth hormone (GH) were examined (22 boys and 12 girls aged 5.3 to 16.2, mean age 11.6±3.2). Bone age lagged behind the chronologic by 4.4+2.1 years, and signs of puberty were absent by the moment of hospitalization in all the children. Clofelin was administered orally in a dose of 0.15 microg/m2 body surface, GH-RH by intravenous jet in a dose of 1 mg/kg. The patients were divided into 3 groups with different response of GH to stimulation with clofelin and GH-RH: group A with a low GH output in both test (the pituitary form); group В with a low reaction to clofelin and normal response to GH-RH (the hypothalamic form); group C with increased level of response to both clofelin and GH-RH (idiopathic dwarfism). Group A included 14 children aged 11.7±2.9. Growth SDS in these children varied from -7.8 to -2.6 (-4.4±1.66). The maximal GH level after clofelin intake was 1.3 ± 1.6 ng/ml and after GH-RH infusion 3.5±2.51 ng/ml in group A. Group В consisted of 7 patients aged 12.0±4.4. Growth SDS in this group varied from -5.6 to 2.5 (- 4.0±1.3). The maximal level of GH in this group was 2.5±2.4 ng/ ml in clofelin test and 15.9±5.4 ng/ml in GH-RH test. Group C included 13 children aged 11.0±4.4, with growth SDS varying from -4.3 to -2.3 (-3.0±0.63). The maximal GH level after clofelin was 15.6±8.2 and after GH-RH 40.8±26.1 ng/ml, this being reliably higher than in group В (U=16.5, p=0.02). Hence, somatotrophic insufficiency was caused by hypothalamic disorders in approximately one-third of our patients.
Hypoglycemic effect of stress exposures and their use for experimental prevention of diabetes mellitus
Authors: Volchegorsky I. A. , Tseilikman V. Е. , Kolesnikov O. L. , Kostin Yu. K. , Kolesnikova A. A. , Skobeleva N. A. , Vyazovsky I. A. , Lifshits R. I.
Published: October 2019

The effects of acute and chronic immobilization stress and of a biogenic stressor, prooxidant (neutrophilokin) on the level of glycemia and resistance to diabetogenic exposures were studied in rats. A relationship between the poststress changes in glycemia and the regime of food intake has been revealed: acute stress on an empty stomach led to hypoglycemia, whereas stress without alimentary deprivation caused hyperglycemia. Prestress of fed animals abolished the hypoglycemic effect of stress on an empty stomach and transformed it into a hyperglycemic reaction which could be prevented by obsidan. Stress-induced hypoglycemia was realized against the background of reduced sensitivity to glucocorticoids and increased insulin sensitivity, with the concentration of the circulating hormone unchanged. The detected regularities are regarded as the mechanism of diabetes preventing action of chronic stress upon alloxan challenge. Repeated immobilization stresses in parallel with obsidan injections are characterized by the highest preventive effect.
Role of magnetic resonance tomography in study of somatotropic insufficiency in children
Authors: Fofanova O. V.
Published: October 2019

The article devoted to the role of magnetic resonance tomography in study of somatotropic insufficiency in children
Efficiency of norditropin, human growth hormone, in the treatment of children with somatotropic insufficiency
Authors: Urmanova Yu. M. , Turakulov Ya. Kh.
Published: October 2019

The article devoted to the efficiency of norditropin, human growth hormone, in the treatment of children with somatotropic insufficiency
Diabetogenic zinc-binding B-cytotoxic com pounds
Authors: Meiramova A. G.
Published: October 2019

The article devoted to the diabetogenic zinc-binding B-cytotoxic com pounds
Contragenealogías del silencio. Una propuesta desde los estudios culturales feministas
Authors: Garzón Martínez María Teresa
Published: October 2019

El presente artículo de reflexión es una deriva en torno a la pregunta sobre si es posible hacer genealogía desde los estudios culturales y feministas o, si mejor, el método al que nos debemos abocar, en la actualidad, cuando preguntamos por las existencias de las mujeres, bajo condiciones de imposibilidad, debe ser contragenealógico. Partiendo de la experiencia de investigar el personaje de La Llorona, su lamento, su silencio, el artículo presenta tres discusiones cardinales: cómo interpretar el silencio de la subalterna, cómo construir un archivo de aquello que no tiene huella y, en consecuencia, qué es afrontar el fracaso cuando se hacen estudios feministas y culturales.
Benjamin con tzotziles, lacandones e hindúes (ejercicio alegórico)
Authors: Mazzoldi Bruno
Published: October 2019

Al procurar acoger el desbordamiento de los sentidos demasiado corrientes de la cita (por igual sumisos a la mecánica del proyecto demostrativo tras rendez-vous y quotation) sea hacia el brote dehiscente de la experiencia vía Walter Benjamin, sea hacia el acontecer irresumible de las narrativas de corte no-occidental, se insinúan intersecciones resonantes entre algunas aventuras nocturnas del materialismo histórico, los movimientos hipnoinsurgentes de las comunidades mayences y ciertas coreografías rituales de la India.
El juego de aquellos que juegan; reflexión acerca de la importancia del juego y su repercusión en la participación social
Authors: Martínez Rebolledo Igor Raphael
Published: October 2019

En las artes escénicas el juego resulta fundamental como técnica de entrenamiento, improvisación y punto de partida para el desarrollo del proceso creativo en la consecución de objetivos como la composición coreográfica e interpretación de un personaje para una puesta en escena. Es el juego también una herramienta social para entender el aprendizaje de un individuo y un camino para exteriorizar las necesidades de las personas; somos lo que aprendemos a través del juego. El presente artículo plantea una reflexión acerca de la importancia del juego como un elemento que define al individuo en la sociedad. Un espacio lúdico que desde nuestra infancia nos permite entender los diferentes roles que existen en la sociedad y los que ejerceremos en el futuro, así como también un instrumento que es fuente de expresión individual y colectiva que constituye un puente para generar la participación social.
Metodología para estandarización de componentes SCADA bajo normas ISA
Authors: Donado Romero Ingrid Johana , Villamizar Rincón Juan Carlos
Published: October 2019

A continuación, se presentan los resultados de un trabajo investigativo desarrollado con el propósito de realizar un aporte a empresas dedicadas a la automatización de procesos industriales como la elaboración de productos alimenticios, fabricación de diferentes insumos, generación eléctrica, entre otros, con miras a alcanzar una mayor calidad y competitividad en sus desarrollos de supervisión, control y adquisición de datos (SCADA, por sus siglas en inglés). Teniendo en cuenta lo anterior, la investigación se centra en la etapa de control, ya que incide directamente en la programación del controlador lógico programable (PLC, por sus siglas en inglés). Se obtiene una metodología conformada por ocho procedimientos de desarrollo estandarizado de funciones o también llamados objetos de programación basada en normas ISA y en buenas prácticas de ingeniería. En particular, se seleccionó como modelo un proceso de producción de papel en el cual se realizó la identificación de los objetos mínimos requeridos y su programación sólida, dando como resultado bloques de funciones eficientes —con más de una docena de valores asociados— aplicables a cualquier tipo de proceso industrial en el que se cuente con procesos automatizados.
Modelos newtonianos y no newtonianos asociados al flujo sanguíneo: revisión
Authors: Montaño Carolina , Rodríguez Nicolás , Camargo Luz Helena
Published: October 2019

El comportamiento y características de la sangre en el sistema circulatorio han generado diversos modelos que pueden ser aplicados para el análisis del flujo sanguíneo, entre los que se incluyen modelos newtonianos y no newtonianos. En esta revisión se presentan once modelos propuestos a partir de parámetros experimentales que incluyen estudios de viscosidad con diferentes velocidades de cizallamiento y densidad asociada a la dinámica de fluidos. Se caracterizaron de acuerdo con métodos, parámetros específicos y valores experimentales utilizados; además, se comparó la eficacia, certeza y precisión de los modelos utilizados.
Abstraction of linked data’s world
Authors: Herrera-Cubides Jhon Francined , Gaona-García Paulo Alonso , Montenegro-Marín Carlos Enrique , Sánchez-Alonso Salvador , Martin-Moncunill David
Published: October 2019

Linked Data, as a strategy of the Semantic Web, is based on application of some basic principles that contribute to the growth of the Web, thus allowing the transit of the Web of Documents to the Web of Data. Developed process by Linked Data is supported in different scenarios, which interact in order to carry out the linking of resources on the Web. Some of these scenarios present a solid technological background, while others propose challenges when they are implemented. This paper aims to identify and expose a generic abstraction of Linked Data, in order to identify problem situations that restrict Linked Data process.
Inclination measurement device for hospital beds’ in ICU
Authors: Naranjo López Daniela , González Jiménez María Alejandra , Buitrago Toro Sebastián , Gallego Londoño Jonathan
Published: October 2019

Ventilator-associated pneumonia is acquired by many patients connected to an artificial airway, causing their death of a great percentage to those who are affected. A close relationship has been found between ventilator-associated pneumonia and hospital beds tilting angle which the patients rest on. The correct position has been established between 30° and 45° to reduce the likelihood of ventilator-associated pneumonia; so a tilt sensor linked to the hospital beds is a good method for measuring. The present article describes an electronic device which was developed able to create a link between an IMU sensor connected to a microcontroller and a Wi-Fi module that allows to display, in a real time graphical interface, located in the control center, the current position of hospital’s beds for being monitored by the nursing staff providing a record of the patients’ status in intensive care and emergency units. Device’s performance was checked by hysteresis and fixed position test along a previously defined time where errors in measurement of inclination remain within a suitable range.
Production engineering immersed in the creative economy
Authors: Villa Garzón Brian , González Bustos Jennifer Paola , Mayorga Morato Manuel Alfonso
Published: October 2019

Currently, the production processes in Colombia are in a phase of continuous improvement, bringing together different specialties that seek to shape and potentiate a product or service, however it is necessary to considerably expand the panorama of possibilities to access the various branches of Creative Culture . From this perspective, entrepreneurship can generate added value that over time can become an opportunity for the sustainable development of the country. This article reviews the relationship between the Creative Economy and Production Engineering, explaining the potential of ideas from unconventional concepts and including them in business models that have managed to be pioneers in this new perspective, all of this through sustainable ideas, cultural heritage , administrative and pedagogical tools aswell as emerging technologies.
Topological alternatives for photovoltaic integration in rural areas
Authors: Molano Gómez Adriana Marcela , Neira Reyes Andrés Felipe , Correa Salazar Luis Hernando , Bernal Alzate Efraín
Published: October 2019

The importance of implementing solar generation systems in rural areas in Colombia lies not only in providing access to the electric power population, but also in the use of current technologies to enhance their socioeconomic growth. The difficulties for its realization lie in technical limitations and access to the site, preventing mayors, heads of council and communities in general can correctly estimate the topology that suits their needs, falling into deceptions by companies that offer them oversized systems or those that do not meet your technical needs. In this document an analysis is made of the different possible topologies for rural areas, offering a methodology for its implementation with two cases of use as real examples.
State of the art in software defined networking (SDN)
Authors: Barrera Pérez Miguel Ángel , Serrato Losada Neider Yampol , Rojas Sánchez Elisa , Mancilla Gaona Giovani
Published: October 2019

The growth of networks at a global level is inevitable due to the increase of users, devices and applications, such as: Internet of Things (IoT), processing and analysis of large amounts of information (Big Data), or streaming audio and video, which has demanded from the systems, greater storage resources and bandwidth. To this purpose, diverse paradigms have emerged for the centralized management of all the components of a network through fully administrable, centralized and dynamic technological platforms; among these is SDN (Software-Defined Networks). This document, consequently, establishes the state-of-art from a documentary research of a categorical type to be used as a frame of reference for research in the area of SDN by the Research Group of New Technologies of Social Application GIDENUTAS ascribed to the University Francisco Jose de Caldas. This is chronologically limited to a review, from 2007 until today, focused on the countries that have promoted the development and implementation of this new paradigm, using databases such as IEEE Xplore, Google Scholar, as well as documents from standardization organizations such as ONF and ITU.
Radar and UAV: georeferencing and airspace surveillance system
Authors: Navarro Roa Jonnathan , Parca Acevedo Félix , Mancilla Gaona Giovani
Published: October 2019

A ¨RADAR¨ system, from the English Acronym ¨Radio Detention and Ranging¨. Better known as ¨Radio Detection and Location¨ RDL.  It is a system for detecting and positioning objects through shipping and reflection of electromagnetic waves in terms of the time of issue and the return of the waves and their speed (calculated by the Doppler effect of the electromagnetic signal received).  Meanwhile, an autonomous unmanned vehicle, also known as Unmanned Aerial Vehicle, UAV, which is defined as an aircraft which does not carry a human operator, and uses aerodynamic forces to provide airlift by itself. Therefore, it can fly autonomously or it can be operated by remote control.  This article focuses on the review of experiences where these two technologies are integrated, particularly UAVSAR (Uninhabited Aerial Vehicle Synthetic Aperture Radar). This is done in order to support research concerning the combination thereof to be applied in georeferencing humanitarian missions or military missions that require monitoring of airspace.
Image analysis aplications in precision agriculture
Authors: Moreno Wilson Fernando , Tangarife Héctor Iván , Escobar Díaz Andrés
Published: October 2019

Unmanned Aircraft Vehicles (UAVs) are currently used for multiple applications in various fields: forestry, geology, the livestock sector and security. Among the most common applications, it is worth to stand out the image acquisition, irrigation, transport, surveillance and others. The study that one presents treats of the implementations that are realized by means of aerial images acquired with UAVs directed to the farming. Images acquired until recent years had been using satellites, however due to the high costs that are incurred and low accessibility to these technologies, UAVs, have become a tool for greater precision and scope for making decisions in agriculture. Information from databases of international magazines, groups and research centers is taken to determine the current state of implementations in Precision Agriculture (PA). This article describes tasks such as: soil preparation; limits and land areas, vegetation monitoring; classification of vegetation, growth, height, plant health; diseases management, pests and weeds, fertilization and inventory developed from analysis of aerial images acquired with UAVs.
Sistema embebido de detección de movimiento mediante visión artificial
Authors: Pérez Miguel , Cavanzo Nisso Gloria Andrea , Villavisán Buitrago Fabian
Published: October 2019

Este artículo presenta el diseño e implementación de un algoritmo de detección de movimiento, basado en la técnica de substracción de fondo, desarrollado en Python e implementado en un sistema Raspberry Pi 3. Se explica detalladamente el algoritmo y sus subsistemas internos, y se hacen pruebas de tiempo de su ejecución montado sobre el sistema embebido con sistema operativo GNU/Linux para determinar si estos algoritmos pueden correr en tiempo real sobre plataformas de bajo costo y tamaño reducido.
Álvaro Barrios recíproco: Los ReadyMade de Duchamp como objetos re-encontrados
Authors: Arias Albeiro
Published: October 2019

Este artículo se deriva de la investigación de tesis doctoral, Álvaro Barrios: cita y apropiación de los ready-made de Marcel Duchamp de 1978- 2013, que tiene como propósito analizar, caracterizar y categorizar los discursos, estrategias y procedimientos usados por el artista conceptual y dibujante colombiano Álvaro Barrios (Cartagena de Indias, 27 de octubre de 1945) cuando incursiona en la cita y apropiación iconográfica de los readymade de Marcel Duchamp en la producción de sus obras.
Minimal Residual Disease, Its Detection and Significance in Hairy-Cell Leukemia
Authors: Žák Pavel , Chrobák Ladislav , Dědič Karel
Published: October 2019

As minimal residual disease (MRD) is considered the detection of hairy cells (HCs) in a patient with hairy cell leukemia (HCL) in complete remission with the absence of detectable HCs by routine morphology of peripheral blood, aspirates and bone marrow core sections, using more sensitive methods of identification as immunohistological staining or polymerase chain reaction (PCR) to detect immunoglobulin heavy chain genes rearrangement. Various monoclonal antibodies (MoAbs) as CD20, DBA.44, B ly-7, HC2, CD25 and CD11c have been applied using immunological staining. There is no standardized technique for identification of MRD. According to the technique used the MRD has been detected in 13% to 100% of patients in complete remission (CR). It may be concluded that many patients, if not all, in stable CR may have residual HCs. Whether MRD will have impact on early relapse or on long term outcome, or whether patients in CR with persistant MRD will remain so, is a matter of a longer follow-up.
Serum Soluble Adhesion Molecules (sICAM-1, sVCAM-1, sE-selectin) and Neopterin in Patients with Sjögren's Syndrome
Authors: Andrýs Ctirad , Krejsek Jan , Slezák Radovan , Drahošová Marcela , Kopecký Otakar
Published: October 2019

Sjögren's syndrome is a systemic autoimmune disease characterized by focal lymphocytic infiltration of the salivary and lacrimal glands. Expression and up-regulation of adhesion molecules and activation of cellular immune system is essential for the migration of inflammatory cells into tissues. Soluble forms of adhesion molecules sICAM-1, sVCAM-1, sE-selectin and neopterin were analyzed in serum of 17 patients with primary Sjögren's syndrome and 11 patients with secondary Sjögren's syndrome together with 26 age-matched healthy blood donors. There were significantly higher serum concentrations (mean ± 1SD) of sICAM-1 (362.0 ± 67.9 ng/ml, p<0.001), sE-selectin (78.7 ± 28.1 ng/ml, p<0.001) and neopterin (17.9 ± 6.4 nmol/l, p<0.001) in primary Sjögren's syndrome patients in comparison to control group (sICAM-1: 128.3 ± 46.9 ng/ml, sE-selectin: 46.3 ± 39.5 ng/ml, and neopterin: 7.6 ± 2.3 nmol/l). Sera from patients with secondary Sjögren's disease contained significantly higher levels of sICAM-1 (356.0 ± 62.4 ng/ml, p<0.001), sE-selectin (65.5 ± 27.0 ng/ml, p<0.05), and neopterin (18.8 ± 9.8 nmol/l, p<0.001) in comparison with control group. There were no significant differences between patients with primary and secondary Sjögren's syndrome in any parameters tested. No statistically significant differences in serum levels of sVCAM-1 were found either in patients with primary or secondary SS compared to control group.
Branch Leadership Optimization Performance in Improving The Performance of Government Banks In West Java
Authors: Samudra Azhari Aziz , Zainal Veithzal Rival , Koto Eryus Amran , Hakim Aziz , Nazriah Ainun , Subagja Iwan Kurniawan
Published: October 2019

As part of finance, every bank, mostly from the government, has an important role in supporting the country's economic recovery from the crisis. The facts show that bank branches are the spearhead of bank operations which are very important in achieving bank goals. That is why every bank branch manager plays an important role in the overall success of the bank's business. The purpose of this study is to analyze several factors that support the optimization of the performance of branch managers of government banks. The results showed that the work of branch managers of state-owned banks affected the performance of Government Banks in West Java.
The Impact of Economic Policy Reforms on Labour and the Nigerian Civil Society: A Stakeholders’ Dialectics
Authors: Fajana Sola
Published: October 2019

The objective of this paper is to examine the impact of current reforms on labour and the civil society in Nigeria. The targeted outcome of the reforms essentially is to reduce poverty and generally improve the lot of the people. It is therefore significant to examine the extent to which the reforms are affecting, positively or negatively, the Nigerian people. This paper therefore provides an overview of the extent to which stakeholders in the Nigerian project are variously affected by current economic reforms, their reactions and the ways in which future policy reforms should be approached. The paper relies on reviews of archival materials and focal interviews of relevant groups to provide insightful information. It was found that reactions have been largely impulsive, lacking coherent future follow-through actions to consolidate initial gains. It is now learnt from lessons of experience that reforms must be appropriate, timely but not impulsive, and well-articulated to achieve the targeted results. It is recommended that policy reforms should be jointly initiated, considered and driven by all constituents to the Nigerian project, to achieve a sense of ownership and high volume commitment.
Training and Development and its Impact on Employees Performance and Productivity "A case Study of district Anantnag Private Sector companies located in the District Anantnag Jammu and Kashmir
Authors: Bhat Ajaz Ahmad
Published: October 2019

This study is all about the training and development  and to understand the affect of its need or necessity on the internal or external management of the organization, this is the only way to design or give framework of the new innovations or creativity and to  implementing the new look over the management of the company we all know organization wants maximum out of the minimum efforts but it needs a proper mentoring of the management and for the same purpose the organization has to adopt the new trends of training sessions  and development in the company for making performance better and better in the upcoming future competition for the research study we have to study about the factor of success for the organization and fulfilling the same objective of the research study we have selected 250 sample size for accessing their information about the training and development programs in their work place.
Implementing Monetary Policy after the 2008 Financial Crisis
Authors: Kallianiotis Ioannis N.
Published: October 2019

Every six weeks or so (9 times during the year), the financial world watches as the Federal Open Market Committee (FOMC) decides on a target interest rate in the federal funds market for the next period. But what happens next? How do policymakers make sure that interest rates in the fed funds market trade within the target range? What will be the effect of the new target rate on the Wall Street and the Main Street? How efficient is so far the monetary policy after the latest global financial crisis? Is the target rate the correct one? The framework that the FOMC uses to implement monetary policy has changed over the last decade and continues to evolve today. Before the 2008 financial crisis, policymakers used one set of instruments to achieve the target rate. However, several policy interventions introduced soon after the crisis drastically altered the landscape of the federal funds market. This new and uncertain environment, with enormous reserves, necessitated a new set of instruments for monetary policy implementation. Lately, after December 2015, as the FOMC began to unwind the effects of these policy interventions, some questions arise: What rules will be followed by the Fed? What happens next as the federal funds market converges to a “new normal”? How effective will be the new policy? Can the Fed prevent a new crisis? The federal funds rate is very low and affects negatively the financial markets (bubbles are growing), the real rates of interest, and the deposit rates, which means the true economic welfare is falling and a new global recession is in preparation, if the latest easy money policy will continue.
Digitale Transformation und die Verbesserung der Wirkung von bibliothekarischen Dienstleistungen
Authors: Tréfás David
Published: October 2019

Bibliotheken sind in den letzten Jahren immer stärker unter Druck von digitalen Konkurrenten geraten. Die Verbesserung der Wirkung ihrer Dienstleistungen ist ein Desiderat von Universitätsbibliotheken. Der digitalen Konkurrenz aus der Privatwirtschaft setzen Bibliotheken jedoch mehrheitlich traditionelle Modelle entgegen. Digitale Transformation bietet den Bibliotheken viele Chancen, sich weiterzuentwickeln und ihre Expertise und ihre Ethik in einem neuen Zeitalter zur Geltung zu bringen. Der Beitrag folgt der Hypothese, wonach die Einführung digitaler Technologien nur dann die Wirkung verbessert, wenn sich Bibliotheken in den Bereichen Strategie, finanzielle Ausstattung, Organisationsstruktur und Führungsverständnis verändern.