bluuebunny/crossref_metadata_2025 huggingface dataset:
Pension policy of Russia in the post-Soviet period: historical aspect
Authors:   Тhe Institute of mining, the Far-Eastern branch of the Russian Academy of Sciences – separate division of the KHFIC of the Far-Eastern branch of the Russian Academy of Sciences, Volkov A. F.
Published: July 2022

The article discusses development of the Russia's pension policy during the historical period of the country's transition to market economic relations. The purpose of the study: analysis of experience in the development of the pension policy of the Russian Federation in the late XX - early XXI centuries. The article presents a description of the main stages of the pension policy. Regional features of the Far-Eastern problem of pension reform at the beginning of the XXI century are shown.Description of the history of formation of the Russia's post-Soviet pension policy in dynamics and in relation to the all-Russian processes that have taken place in the country since the first attempts to modernize the mandatory pension system of the RSFSR at the end of the 20th century and their subsequent reform at the beginning of the 21st century, as well as with the next stages of modernization and development of the pension system of the Russian Federation in the first decades of the 21st century, is presented. The author concluded about the unreliability of market insurance pension systems based on funded principles and the need to continue finding the optimal model of the state pension policy in the new realities of the political and socio-economic development of the global society.
Creativity and crisis – new resources of commercial organization in the conditions of digital transformation
Authors:   The Pyatigorsk State University, Salogub A. M.
Published: July 2022

In difficult, unpredictable, crisis conditions, organizations are forced to look for new approaches to maintain their competitiveness in the market.The main goal of scientific work is to analyze approaches to transforming the management style of a modern organization. The author notes that creativity and crisis become the powerful resources for changing the company in the context of digital transformation. The article substantiates theoretical provisions on the problem of creativity as a scientific category, developed practical recommendations for organizing the creative process, creating a productive creative environment, using the potential of individual and team creativity, determined the parameters and conditions for cooperation between corporations and the creative class in the person of free agents, leaders of movements and communities. The need to transform the models of organization management in a crisis using the possibilities of creativity as a new resource of the organization is justified.
One of the actuators of the living standard leveling mechanism population of the North
Authors:   The Federal research center of YSC SB RAS, Pakhomov А. A. , Solomonov M. P. ,   The Federal research center of YSC SB RAS
Published: July 2022

The article presents the arguments for the activation of one of the mechanisms proposed by the authors in previous issues of the journal to equalize the living standards of the population in the regions of the Far North and areas equated to them. The state? Being in a symbiosis of liberal and dirigiste concepts of development, in the North, is forced to act as the main player in the market. In the long term, the main player is faced with the task of sustainable development of the living conditions of the population living in the North, because the real resource-based economy, after all, is the economy of a visible perspective, and not of future generations of Russians. The desire of people for comfort cannot be prevented and it is unlikely that it will be possible to increase the population in the North. The state needs to plan in the long run for today’s current population in the North. The determining factor in improving the living standards of the population in the North is the high-quality heat supply of utility, social and industrial facilities. Heat supply in the North is at the same time a factor in the rise in production costs. Its transition everywhere to equal conditions for the government to equalize tariffs for thermal energy to the average Russian level. Equalization of heat energy tariffs prior to this transition will create dependent conditions for consumers. The main brake on the transition is the lack of standards that fully take into account the loss of resistance to heat transfer by the enclosing structures of buildings and structures as they wear out. High specific energy costs for expenses with wear and tear of observers have the ability to prevent the installation of common house meters, respectively, the entire article about the beginning of the experience of rationing energy consumption by growth with depreciation in the area of responsibility of Sakha (Yakutia) and mass events to stimulate energy conservation.
Exploring the China's innovative library publishing services in the age of big data and the Internet
Authors:   The Institute of Russia of the Academy of Social Sciences, Liu Bo
Published: July 2022

Development of big data and the Internet opens up opportunities for the innovative publishing models for Chinese libraries. This article analyzes feasibility of the library publishing services in the context of big data and the Internet, outlines the development opportunities provided by big data and the Internet environment for the library publishing services, and combines the types of library publishing service models against the background of big data and the Internet and puts forward a strategy for innovative model of the library publishing services in China.
Internationalization of educational activities of the Russian universities: the Far-Eastern development vector
Authors:   The Sholom-Aleichem Priamurskiy State University, Nevelichko L.G. , Bazhenova N.G. ,   The Sholom-Aleichem Priamurskiy State University, Bogachenko N.G. ,   The Sholom-Aleichem Priamurskiy State University, Bazhenov R.I. ,   The Sholom-Aleichem Priamurskiy State University, Vorotilkina I.M. ,   The Sholom-Aleichem Priamurskiy State University
Published: July 2022

The article is devoted to the problem of attracting foreign students to the Russian universities. Particular attention is paid to the ways of forming a positive image and factors of attractiveness of educational organizations of higher education in the Far East for potential students. The article considers several areas of development of the indicated problem. First of all, internationalization of education and increase in the number of foreign students is the effective fulfillment of modern request for socio-economic development for the highly professional personnel. Currently, the most urgent tasks are to create necessary conditions to prevent the outflow of foreign students from Russia, thereby preserving their contingent by maintaining the high quality of education with the development and widespread introduction of new learning formats into the educational process: online technologies, hybrid forms of education. The article notes that for Russia, which has a powerful export potential of education system, finding the ways to increase the competitiveness of Russian universities in the world educational space is a current priority. The article pays special attention to the issue of attracting foreign students to the universities in the Far East, especially from the PRC. Close proximity of the Far-Eastern region to China and the need to identify resources that ensure competitive positions for the regional universities in attracting Chinese students justify the prospects for sociological developments in this area. Based on the surveys of foreign students, graduates and potential applicants, the authors of this article identified priority areas in the development of educational potential of the Far-Eastern universities and increasing their attractiveness for the foreign students, refuted stereotypical ideas that foreign students from the low-income families and having a low level of education enter the Russian Far-Eastern universities. The conclusions to which the authors come are addressed to the university leaders, teachers, as well as officials of the government and business bodies interested in the development of the Far-Eastern territories.
Implementation of the priority project «Export of education» in sociological dimension
Authors:   The Far-Eastern statuniversite y of communication, Tyurina Yu. A.
Published: July 2022

Implementation of the priority project «Export of education in sociological dimension annotation due to historical, geopolitical and economic reasons, higher education in the regions of Russia is in different conditions in implementation of the federal project «Export of Education». The main component of the project, which universities are focused on in organizing international activities, today is the indicator - the number of foreign students in a certain ratio with the number of university students. However, the key strategic goal of the project is to increase the competitiveness of Russian education in the international market of educational services due to the attractiveness of domestic educational programs for foreign citizens, improve their living conditions during the period of study in Russia, which, ultimately, should significantly increase the amount of revenue from export of educational services. Organization of international activities and work with foreign students in universities, as well as the implementation of the indicator «number of foreign students», within the framework of the project, became the subject of the presented study, the main methods of which were determined: non-standardized interviews of leaders in charge of international activities of universities, and a survey foreign students of universities of the Khabarovsk territory. The obtained results allow us state that the project «Education Export» does not take into account the regional conditions for its implementation, the implementation of quantitative indicators is not additionally funded and is left to the mercy of universities. Foreign students of the region do not demonstrate complete satisfaction with education and organization of life. All this, on the one hand, is explained by the peculiarities of the motivation for their stay in the universities of Russia - the Khabarovsk territory, on the other hand, by the domestic specifics of the higher education system.
Formation of healthy behavior among the students of medical university: to the development of the concept of research
Authors:   The Pacific state medical university of the Ministry of Health of Russia, Fedorishcheva E.K.
Published: July 2022

The article discusses theoretical and applied aspects of introduction of the innovative health-saving technologies in preparation of the highest echelon of medical industry in the Far-East region. Based on a comparative analysis of the results of current research and fundamental sociological sources covering the issues of personal and group behavior of the students of medical universities in relation to health, as well as the results of previously published own observations, taking into account the newly identified factors that affect the behavioral models of the modern student youth, in this article an attempt to comprehend and conceptualize the health-forming algorithm at the medical university, highlight the main directions of influence on the behavioral stereotypes and patterns of students, the formation of a rational attitude to the physical and psychological status, and the reduction of morbidity in the educational space is made. The proposed concept assumes a fundamentally new scheme for reducing the incidence rate and introducing previously unused methods of health saving among students. The structural-functional approach used in the development of the postulates of the concept makes it possible to determine and rank the significance of new functional relationships in the educational environment of a medical university, and the axiological approach to identify the most important values of students when making decisions regarding their own health. The article pays great attention to the applied aspects of health saving: the necessity of using interactive technologies and active interventions by the IT departments of the university in the existing network publics, popular among the students, generating original messages that initiate the formation of the need for introspection, obtaining new knowledge among students of medical specialties is substantiated. About the social value of health-saving behavior as a tool to improve social status, ways to implement the information are received.
JUDICIALIZAÇÃO DAS AÇÕES AFIRMATIVAS NO BRASIL:
Authors: Eidelwein Silveira Gabriel , Gonçalves Palha do Nascimento Gisele , Luz Kaélio Francisco , Eidelwein Tamires
Published: July 2022

O processo escravocrata, apesar de findado há muitos anos, deixou marcas que repercutem em diversos campos da vida humana, sobretudo o da educação, o qual este trabalho propõe-se a discutir. Apesar desse histórico excludente, a adesão de ações afirmativas de cotas raciais para o acesso à educação brasileira é um caminho válido, tendo sua constitucionalidade confirmada pela improcedência da Arguição de Descumprimento de Preceito Fundamental 186/DF - ADPF 186, julgada no ano de 2012. A oportunidade do acesso educacional é um direito social assegurado pela Constituição Federal que visa a transformação do status quo, por isso, refletir sobre as concepções meritocráticas que permitem uma perpetuação das desigualdades, também faz parte dos objetivos dessa pesquisa.
CONFLITOS SOCIOTERRITORIAIS NO TERRITÓRIO QUILOMBOLA DO SAPÊ DO NORTE E A COVID-19
Authors: Barcellos Gilsa Helena , Lyra Ana Paula , Nascimento Fany Serafim , Corrêa Wakyla
Published: July 2022

Este artigo trata dos conflitos socioterritoriais vivenciados pelas comunidades quilombolas do Sapê do Norte, localizadas no extremo norte do Espírito Santo. Para a realização do estudo foram utilizadas como procedimentos metodológicos as pesquisas bibliográfica e documental. É uma investigação que vincula-se ao Núcleo de Estudos Sobre Violência, Segurança Pública e Direitos Humanos da Universidade Federal do Espírito Santo. Os conflitos territoriais vivenciados pelas comunidades a partir de meados do século XX estabelecem uma relação direta com o projeto de urbanização do território brasileiro embalado pela expansão capitalista. O processo de expropriação territorial vivenciado levou à extinção 68 comunidades, restando, na atualidade, 32 apenas. Mais recentemente, no contexto da pandemia da Covid-19, novos adversários se apresentaram: especuladores imobiliários. Por ser um território que se localiza em uma região litorânea, cresceram os interesses desse mercado sobre a região. Mas, dialeticamente, nessa dinâmica perversa, o povo quilombola luta e resiste.
Versão Completa
Authors: Motta Sérgio
Published: July 2022

Capa, Sumário, Editoria e Artigos
LA GRAN CIUDAD DE MÉXICO
Authors: Luna Gómez Luis Alberto
Published: July 2022

El objetivo es mostrar en la Zona Metropolitana de la Ciudad de México (ZMCM) el aumento de la desigualdad desde el periodo de sustitución de importaciones hasta el neoliberalismo, las estrategias para resolver la crisis del aumento del desempleo, la desregulación, la apertura comercial, en consecuencia, y las transferencias fiscales se hicieron en infraestructura para la movilidad. En la región, en particular, no se ha avanzado en la redistribución, por el contrario, avanza el aislamiento de la clase subalterna, a través de velos como los derechos del individuo, fantasías ideológicas y falsas seguridades, que amalgaman la interacción, la socialización. Uno de los errores es dirigir las transferencias a la infraestructura de áreas especializadas. Sin un transporte público de calidad, calles saludables para peatones, ciclistas y motociclistas. Un resultado del proyecto de clase favorecida por el que el valor de la producción del paisaje, a través de símbolos de prestigio y descrédito. La investigación se realizó a partir del análisis de Encuesta Origen Destino 2007 y 2017. El énfasis está en la observación reportada a pie. Se calculó la densidad, la tasa, la relación entre la población y la presión del suelo mediante isopletas, líneas imaginarias de 7 km² entre cada una, para analizar la conectividad y la accesibilidad de las más de 200 pedanías que componen los 76 municipios de la región.
GEOGRAFIA E ANTIRRACISMO NA EDUCAÇÃO
Authors: Rocha Bruna Machado da
Published: July 2022

Este artigo propõe analisar autores que abordam em suas obras como a Geografia estuda e concebe a racialidade.  Nesse sentido, faz-se necessário compartilhar e enaltecer autores que já contribuem para caminhos antirracistas na Geografia. Analisando as Competências específicas de Geografia para o Ensino Fundamental da Base Nacional Comum Curricular (BNCC), sugerem-se também direcionamentos para a instrumentalização de diretrizes que pautem práticas pedagógicas intencionadas ao antirracismo.
Uso de recursos didácticos y tecnologías digitales por parte de personas docentes itinerantes en Costa Rica
Authors: Paniagua-Esquivel Cristina
Published: July 2022

Las personas docentes itinerantes se caracterizan por dar apoyo educativo a población que tiene problemas de aprendizaje, discapacidades, problemas emocionales e, incluso, personas que imparten materias complementarias o en otros idiomas. Para estas personas que pueden trabajar hasta en más de cinco centros, es importante contar con un alto manejo de diseño de recursos digitales; sin embargo, no se ha encontrado información sobre los recursos que realizan. El presente artículo es parte del I Censo Nacional de Tecnologías Digitales en Educación, realizado por el Ministerio de Educación Pública de Costa Rica con colaboración de la Universidad de Costa Rica y desarrollado entre 2016 y 2017. Es una investigación cuantitativa, tipo censo, que tomó la información de 1019 docentes de servicio itinerante. El instrumento fue un cuestionario autoaplicado, enviado por la plataforma de encuestas en línea LimeSurvey. Se utilizaron estadísticos descriptivos y un coeficiente de correlación de Spearman para mostrar tanto el nivel de uso de recursos didácticos digitales, que es una de las competencias digitales, como su relación con la actitud y capacitaciones. El resultado principal revela que la mayoría utiliza recursos digitales en su práctica docente y tiene un uso entre intermedio y avanzado, una actitud alta y un nivel de capacitación bajo. A pesar de que la relación es débil, invita a la reflexión y al aumento de los potenciales cursos y el acceso a recursos.
Generatividad y propensión a enseñar en educadores rurales chilenos: saberes educativos desde la perspectiva narrativagenerativa
Authors: Sandoval Obando Eduardo Enrique , Calvo Muñoz Carlos Manuel
Published: July 2022

Las historias de vida del profesorado rural son una herramienta histórica y cultural relevante para develar aquellas prácticas y criterios de acción pedagógica potencialmente generativos desplegados dentro y fuera de la institución escolar rural. Como objetivo, se busca interpretar y comprender, desde la perspectiva narrativa generativa, las pautas de comportamiento construidas por el profesorado rural chileno, lo cual contribuye a la sistematización de nuevas posibilidades de comprensión de la profesionalidad docente rural. Desde lo metodológico, se adopta un enfoque interpretativo cualitativo, siguiendo un diseño descriptivo, exploratorio y transversal. La muestra es de carácter intencional y está conformada por 12 educadores, quienes poseen, en promedio, treinta y tres años de experiencia docente en escuelas rurales en las regiones Metropolitana, La Araucanía y los Ríos (Chile). Para la recolección de los datos, se utilizaron entrevistas en profundidad desde la perspectiva narrativa generativa. Posteriormente, los relatos fueron sometidos al análisis de contenido, siguiendo la lógica de la teoría fundamentada. Los principales resultados evidencian que el profesorado exhibe prácticas y criterios de acción pedagógica potencialmente generativos, caracterizados por su compromiso con la labor educativa, el afecto positivo y la flexibilidad. Esto le permite construir relaciones interpersonales positivas y recíprocas con el alumnado. Del mismo modo, la propensión a enseñar que orienta su quehacer profesional favorece la construcción de aprendizajes educativos relevantes y con pertinencia histórica-sociocultural para el alumnado y sus comunidades de origen
Conectando la educación matemática infantil y el pensamiento computacional: aprendizaje de patrones de repetición con el robot educativo programable Cubetto®
Authors: Alsina Angel , Acosta Yenisel
Published: July 2022

En los últimos años se han ido fortaleciendo los vínculos entre la educación matemática y el pensamiento computacional, ya que ambas áreas requieren de diversas habilidades en torno a la resolución de problemas; sin embargo, el profesorado de la niñez de las primeras edades ha tenido una escasa formación para implementar actividades que promuevan este pensamiento en el aula de matemática. En este sentido, el objetivo de este artículo es indagar acerca de las conexiones existentes entre la educación matemática infantil y el pensamiento computacional, para que el profesorado de la población de las primeras edades pueda diseñar e implementar actividades que permitan desarrollar habilidades de estos dos tipos de pensamiento de manera integrada. Para lograr este propósito, se describe y analiza una experiencia para aprender patrones de repetición a través del robot educativo programable Cubetto®. La actividad se implementa con 24 niños de 5 años de edad, de un colegio público de Girona (España) y los resultados muestran que una parte importante de los niños de esta edad representan de manera correcta el patrón (62.5%), siendo la representación gráfica la más habitual entre los participantes que resuelven correctamente las tareas (86.7%). Se concluye que, en el contexto actual, es necesario seguir diseñando actividades que promuevan el desarrollo de conocimientos matemáticos de manera lúdica, a través de una gestión de la enseñanza basada en habilidades como la resolución de problemas, el razonamiento, la comunicación, las conexiones y la representación, a la vez que se van desarrollando también destrezas digitales y el pensamiento lógico y computacional.
Necesidades de cualificación docente de la EFTP costarricense: primeros resultados del Proyecto CoRiVET
Authors: Rommel Irina , Vargas Méndez Monserrat
Published: July 2022

La Educación y Formación Técnica Profesional (EFTP) en Costa Rica ha recibido una gran atención social, política y económica debido a la creciente necesidad de mano de obra cualificada en diferentes sectores para diversificar la economía y reducir las desigualdades sociales. El nivel actual de desempleo, especialmente entre los jóvenes, muestra la importancia de la formación profesional inicial y llama la atención no sólo en la agenda política, así en torno a la discusión constante sobre la importancia y el papel de docentes formadores de futuros profesionales para la EFTP costarricense. Se necesitan profesores y profesoras cualificadas que conozcan las características y especificidades de la EFTP y que puedan responder con competencias pedagógicas y didácticas. Este manuscrito analiza la importancia del papel de la EFTP en y para Costa Rica, en el contexto del profesorado, a partir del ejemplo el proyecto bilateral entre Costa Rica y Alemania titulado: Educación y Formación Técnica Profesional en Costa Rica (CoRiVET). Una de las principales conclusiones sostiene que la formación del profesorado para la EFTP en Costa Rica presenta debilidades en el campo de la pedagogía, la didáctica profesional y la capacitación de las personas docentes; todos ellos constituyen los retos más urgentes por resolver, con miras a fortalecer el sistema, así como al desarrollo de competencias a través de programas de capacitación.
Risk factors and prediction model for endometrial polyps in patients with endometriosis: A Retrospective Study
Authors: Song Zhimin , Wan Xiaojie , Chen Jianpeng , Zhang Tao , Zhou Jianhong , Luo Jie , Li Jingyi
Published: July 2022

Objective Analyze the differences in the laboratory indexes and baseline
clinical characteristics between the endometriosis(EMs) patients with or
without combination of endometrial polyps(EPs), and establish an
efficient combined prediction model to predict endometrial polyps in
endometrial patients. Design Retrospective study Setting Women’s
Hospital, Zhejiang University School of Medicine, China, from August 1,
2020, to July 31, 2021 Population 1250 endometriosis patients Methods
Logistic regression analysis was used to establish a combined diagnostic
model. RESULTS Compared with endometriosis patients without
EPs，endometriosis patients combined with EPs had significantly higher
age, gravidity, parity, body mass index (BMI), systolic blood
pressure(SBP), diastolic blood pressure(DBP), luteinizing hormone (LH ),
estradiol (E2), platelet(PLT), total cholesterol (TC), low-density
lipoprotein cholesterol (LDL-C ), fasting plasma glucose (FPG), and had
significantly lower hemoglobin (HGB) and white blood cells(WBCs)
(P＜0.05). The combined prediction model for endometrial polyps in
patients with endometriosis including BMI, DBP, gravidity, parity,
LH，WBCs, HGB, TC, FPG has been established. The ROC curve showed that
the combined diagnostic model reached area under the curve of
0.78(0.75-0.82, p＜0.001). CONCLUSION Compared with endometriosis
patients without EPs，endometriosis patients combined with EPs had some
metabolic changes. The combined diagnostic model of
BMI，DBP，gravidity，parity，LH，WBCs, HGB, TC, FPG may provide a new
approach for the early diagnosis and precise treatment of endometrial
polyps in endometriosis patients.
Differential Privacy Distributed Logistic Regression with Objective Function Perturbation
Authors: Zou Bin , Yang Haibo , Ji Yulong , Fu Yingxiong
Published: July 2022

Distributed learning is a very effective divide-and-conquer strategy for
dealing with big data. As distributed learning algorithms become more
and more mature, network security issues including the risk of privacy
disclosure of personal sensitive data, have attracted high attention and
vigilance. Differential privacy is an important method that maximizes
the accuracy of a data query while minimizing the chance of identifying
its records when querying from this data. The known differential privacy
distributed learning algorithms are based on variable perturbation and
the variable perturbation method may be non-convergence and the
experimental results usually have large deviations. Therefore, in this
article we consider differential privacy distributed learning algorithm
based on objective function perturbation. We first propose a new
distributed logistic regression algorithm based on objective function
perturbation (DLR-OFP). We prove that the proposed DLR-OFP satisfies
differential privacy, and obtain a fast convergence rate by introducing
a new acceleration factor for the gradient descent method. The numerical
experiments based on benchmark data show that the proposed DLR-OFP
algorithm has fast convergence rate and good privacy protection ability.
Cardiac toxicity associated with pharmacokinetic drug–drug interaction between crizotinib and sofosbuvir/velpatasvir: a case report
Authors: Monribot Anthia , Huillard Olivier , Khoudour Nihel , Préta Laure-Hélène , Blanchet Benoit , Cabanes Laure , Batista Rui , Pallet Nicolas , Chouchana Laurent , Goldwasser François , Sogni Philippe , Thomas-Schoemann Audrey
Published: July 2022

This case report describes of a pharmacokinetic drug–drug interaction
between crizotinib, a tyrosine kinase inhibitor, and
sofosbuvir/velpatasvir, a direct-acting antiviral drug, leading to
cardiac toxicity. A 75-year-old man, with no cardiovascular history but
a diagnosis of metastatic non-small cell lung cancer with MET exon-14
deletion and hepatitis C virus infection genotype 1A, received both
crizotinib and sofosbuvir/velpatasvir. Crizotinib was well tolerated,
but 1 week after sofosbuvir/velpatasvir initiation, the patient
experienced bilateral lower-limb edema and class III NYHA dyspnea. We
assumed that increased exposure to crizotinib could account for this
cardiac toxicity. Drug causality was probable according to the Naranjo
scale. We hypothesized a reciprocal interaction between crizotinib and
velpatasvir, mediated by both cytochrome 3A4 (CYP3A4) and P-glycoprotein
(P-gp). Clinicians should be aware of the risk of drug–drug
interactions between direct-acting antiviral agents that inhibit CYP3A4
(glecaprevir) and/or P-gp (voxilaprevir) and anticancer tyrosine kinase
inhibitors that are mostly CYP3A4 and/or P-gp substrates (gefitinib,
afatinib, erlotinib, crizotinib, ceritinib, lorlatinib, brigatinib,
capmatinib etc.).
Shyer fish are superior swimmers in Siberian sturgeon (Acipenser baerii)
Authors: Xiang Lingli , Mi Xiangyuan , Li Weiwei , Dang Yingchao , Zhang Chaoshuo , Zeng Yu , Jiang Wei , Du Hao , Twardek William , Cooke Steven , Bao Jianghui , Duan Ming
Published: July 2022

Differences in individual personality are common amongst animals, which
can play an ecological and evolutionary role given links to fitness.
Personality affects animal life processes and outputs (e.g., behavior,
life history, growth, survival, reproduction), and has become a common
theme in animal behavioral ecology research. In the present study, we
used Siberian Sturgeon to explore how personality traits of boldness and
shyness are related to swimming performance, post exercise recovery and
phenotypic morphology. Firstly, our results indicated that the Siberian
sturgeon juveniles of shyness were better swimmers, validating
evolutionary biology trade-off theory. The critical swimming speed
(Ucrit) of the shy groups was higher than that of the bold groups.
Secondly, the shy groups were more resilient after exercise fatigue. The
swimming fatigue recovery ability, the glucose and lactic acid
concentration recovery ability of shy groups were greater than that of
bold groups. Thirdly, the shy groups were more streamlined. Compared
with bold groups, shy groups had smaller caudate stalk lengths, caudate
stalk heights, superior caudal lobes, and inferior caudal lobes. These
research results further enrich the theoretical viewpoints of fish
behavior biology, more importantly, which provided a good example for
studying the relationship between sturgeon’s “personality” and
swimming performance.
PEGylated Paclitaxel Nanomedicine Meets 3D Confinement: Cytotoxicity and Cell Behaviors
Authors: Lin Wenhai , Xu Yuanhao , Hong Xiao , Pang Stella
Published: July 2022

It is beneficial to investigate the effect of nanomedicines on cancer
cell behaviors on three-dimensional (3D) platforms for evaluating and
developing novel antitumor nanomedicines in vitro.
Two-dimensional flat surface is widely used to study the cytotoxicity of
nanomedicines on cancer cells, and there is little work using 3D
confinement to assess the effect of nanomedicine on cancer cells. In
this work, PEGylated paclitaxel nanoparticles (PEG-PTX NPs) were applied
for the first time to treat nasopharyngeal carcinoma (NPC43) cells in 3D
confinement which consisted of microwells with different sizes and a
glass cover. The cytotoxicity of the small molecule drug paclitaxel
(PTX) and PEG-PTX NPs were studied in microwells with sizes of 50×50,
100×100, and 150×150 μm and with covers. After NPC43
cells were treated with PTX and PEG-PTX NPs, the cell migration speed
and cell morphology were analyzed in different microwells without and
with covers. The relationship between the cytotoxicity from drugs, the
size effect from microwells, and cell behaviors were analyzed. These
results not only show the effect of 3D confinement on cytotoxicity of
nanomedicines and cell behaviors, but also provide a novel method to
screen anticancer drugs and evaluate the cell behaviors in vitro.
Harlequin Ichthyosis: A case image from Syria
Authors: Al-Dabbagh Jacob , Daabool Rajaa , Hatem Reem , Al-Soufi Lina
Published: July 2022

Harlequin ichthyosis is a rare autosomal recessive congenital ichthyosis
with a distinct phenotypic appearance. We report a male baby with
harlequin ichthyosis who was born to consanguineous parents that have a
previous female baby who was diagnosed with harlequin ichthyosis.
Uncomfortable Knowledge: Toward a Pedagogy of Reflexivity
Authors: Singleton Benedict , Gillette Maris Boyd , Burman Anders , Blanes Ruy
Published: July 2022

Reflexivity is a hallmark of good ethnography and many consider it a defining characteristic of anthropology. It is thus surprising that anthropologists have not paid more attention to how we teach students to be reflexive. Many of us learn reflexivity by making mistakes in the field, yet discussions of anthropological faux pas and their potential contributions to reflexive learning are typically limited to informal settings and occluded or heavily curated within our research outputs. In this article we employ analytic tools from the theory of sociocultural viability, in particular the notions of clumsiness, elegance, and uncomfortable knowledge, to contribute to developing a more explicit pedagogy of reflexivity. Since reading ethnographies plays a major role in how we teach anthropology, we argue that anthropologists should do more in their publications to highlight how awkward moments can deepen reflexivity. To advance this agenda, we provide cases of uncomfortable knowledge drawn from our own field experiences, highlighting how the social, emotional and embodied awkwardness of each situation contributed to acquiring reflexive insights. This article is thus a call to initiate prospective researchers earlier into the messy backstage of anthropological research, including by clarifying how the embodied and affective aspects of our interactions offer potential for deepening reflexive knowledge. In the hopes of facilitating the development of our pedagogies of reflexivity, we conclude the text with four recommendations that we feel will encourage reflexive learning from awkward fieldwork encounters.
Plany rozwoju turystyki w strategiach gmin turystycznych
Authors: Zontek Zbigniew
Published: July 2022

W artykule wskazano na rolę strategii w programowaniu rozwoju turystyki w gminach turystycznych. Przedstawiono zagadnienia dotyczące strategii w turystyce oraz roli samorządu gminy w kształtowaniu gospodarki turystycznej. Obszarem badawczym jest subregion południowy województwa śląskiego, którego atrakcyjność turystyczną scharakteryzowano na podstawie danych statystycznych. W artykule dokonano oceny diagnostycznej strategii rozwoju gmin badanego regionu.
Postrzeganie i ocena atrakcji turystycznych przez turystów jako czynnik implikujący programy rozwoju i promocji produktów turystycznych regionu
Authors: Lipianin-Zontek Ewa , Szewczyk Irena
Published: July 2022

Jednym z ważniejszych elementów składowych systemu turystyki są atrakcje turystyczne. To właśnie atrakcje stanowią siłę napędową ruchu turystycznego będąc magnesem przyciągającym turystę do celu podróży i stanowią sedno produktu turystycznego. Pozwalają identyfikować regiony, miejscowości, określają ich tożsamość i kształtują wizerunek. W niniejszym opracowaniu wskazano na rolę atrakcji turystycznych w kreowaniu programu rozwoju i promocji produktów turystycznych regionu. W tym celu wskazano na ujęcie teoretyczne atrakcji turystycznych, dokonano przeglądu i oceny atrakcji turystycznych gminy Czernichów leżącej w woj. śląskim. Wskazano na atuty i możliwości kreowania nowych produktów turystycznych.
Prawa pasażerów w ocenie respondentów
Authors: Ozimek Irena , Krawczyk Przemysław
Published: July 2022

Głównym celem badań była ocena poziomu przestrzegania praw pasażerów w Polsce w świetle badania ankietowego dotyczącego zdiagnozowania świadomości osób korzystających z transportu w zakresie praw i obowiązków przysługujących pasażerom podczas przewozu, a także istniejących regulacji prawnych. Prowadzenie działalności w zakresie transportu pasażerskiego regulowane jest prawnie. Każda gałąź transportu ma swoją specyfikę, która wyklucza stworzenie jednego uniwersalnego aktu prawnego regulującego przewóz osób. W przypadku złamania prawa lub zaniedbania praw przez przewoźnika, najbardziej przydatna byłaby pasażerowi wiedza na temat możliwych sposobów dochodzenia roszczeń. Niestety deklarowany przez respondentów poziom wiedzy nie jest wykorzystywany przez nich w praktyce, ponieważ liczba skarg i wysuwanych roszczeń jest niewielka, w porównaniu do liczby osób uważających się za pokrzywdzonych. Dlatego tak ważne staje się prowadzenie działalności edukacyjnej i informacyjnej przez organizacje i instytucje działające na rzecz ochrony praw pasażerów.
Production & Characterisation of Fermented Coconut Water and a Report on Its Health Benefits
Authors: V Ramamurthy
Published: July 2022

Coconut water known as nutritive liquid and a natural medium for microbial growth is obtained from the endosperm of coconuts (Cocos nucifera) and is largely consumed in tropical countries. Fermentation with known culture of microbes gives desirable quality and more shelf life to this perishable drink. Fermentation of coconut water to prepare a beverage of high health benefits and commercial value was attempted. Tender coconut was fermented with Saccharomyces cerevisiae yeast and observed for the fermentative changes in around 15 days. The sensory analysis of obtained fermented drink was done to prove the quality of fermented product. The physiochemical analysis revealed that the pH was 4 to 5 pH on 15th day of fermentation and was stable. Fermented coconut water prepared contained textural element tannin in very low concentration as desired. Tannin content was found in range of 0.016 to 0.25%. The phenol content was measured using folin cioclteu assay method and was 33.8 % in finished drink. The alcohol content was 7-8% in finished drink as measured by spectrophotometry. Fermented coconut water retained active enzymes like peroxidase, catalase, and dehydrogenase that aids in the digestion and metabolism of food, and was proved by enzyme activity tests such as Amylase test, catalase test, peroxidase test. Coconut water is known to be flourished with amino acids and the presence of amino acids like tyrosine, tryptophan, alanine and valine in fermented coconut water was confirmed by paper chromatography. GC-MS analysis of fermented coconut water showed the presence of compounds - benzene ethanol, cyclohexane, gamma sitosterol, di alpha tocopherol. These compounds are known to support antibacterial, antithrombotic and antioxidant properties. Protein prediction using Swiss prediction was done to identify the available ligands in the Bio active compounds reported by Gas Chromatogram.
Phenolic Acids in Red Wine Interact Directly with the Protein Fraction of Saliva
Authors: R Lopez-Solis
Published: July 2022

Wine-evoked astringency is usually associated with interactions between proanthocyanidins and salivary proteins. Limited information exists about interaction of other wine phenolic compounds with saliva. This study assessed the ability of single phenolic acids and mixes of phenolic acids to interact with salivary protein. Protein diffusion on cellulose membranes and protein precipitation assays were conducted. Single phenolic acids (PA), excepting tannic acid (T), showed concentrationdependent reduction of the area of diffusion of the diffusible salivary protein. PAs were weak precipitants of the salivary protein but strong inducers of soluble PA-salivary protein complexes. T precipitated non-diffusible salivary proteins without effect on the diffusible protein. Compared to single PAs, mixes of gallic acid (G) and PAs showed similar effects regarding inhibition of protein diffusion and formation of soluble PA-protein complexes. Contrarily, T interfered with both effects of PAs. It is concluded that PAs interact directly and diversely with the salivary protein and thence may cause astringency
Probiotics, Prebiotics and Fruit and Vegetable Fiber Improved the Gastrointestinal Tract and Increased Immunity: A Randomized, SingleBlind, Placebo-Controlled Parallel Trial
Authors: Chiang Chi-Fu
Published: July 2022

The intestinal tract is the largest immune organ in the human body. A healthy gut will block bacteria, viruses, molds, parasites, and other attacks. Studies have shown that probiotics can stabilize the intestinal barrier and improve immunity, while prebiotics can help probiotics multiply and grow effectively in the human gut. Dietary fibers increase the frequency of gastrointestinal motility. This study used the combination formula of probiotics, prebiotics, and fruit and vegetable fiber to explore its effects on gastrointestinal health and improving immunity. The study recruited 50 subjects and randomly assigned two groups, the placebo group and the probiotic fruit and vegetable fiber powder group (PF formula). Subjects were measured in body position measurement, blood and stool collection, dietary questionnaire, and somatosensory questionnaire at weeks 0, and 12. The PF formula increased IgG, IgM, and IL-10 and decreased IL-6, IL-12, IFN-γ, and TNF-⍺ compared to baseline (week 0). The PF formula increased the frequency of bowel movements, improved flatulence, stomach pain, hard stools, constipation, and diarrhea. It also reduced headache, muscle pain, and dizziness compared to baseline. Finally, the PF formula increased the abundance of beneficial bacteria Porphyromonadaceae and Parabacteroides and decreased the abundance of harmful bacteria Clostridiaceae. The PF formula had the effect of gastrointestinal health care and enhanced immunity
Studies on Production and In Vitro Antibacterial Potentials of Violacein from Chromobacterium Violaceum Isolated from Otamiri River in Owerri, Imo State
Authors: JN Dike-Ndudim
Published: July 2022

Chromobacterium violaceum was isolated from Otammiri River in Owerri, Imo State. The organism was isolated using nutrient agar and identified based on cultural and biochemical characteristics. The isolate produced violacein pigment on nutrient broth and the violacein produced was quantified and extracted with ethanol. The effects of different temperatures (4°C, 25°C, 30°C, 37°C, 40°C, 52°C), pH (4.0, 4.5, 5.0, 5.5, 6.0, 6.5, 7.0, 7.5, 8.0, 8.5, 9.0), incubation period (12hr, 24hr, 36hr, 48hr, 60hr, 72hr, 84hr, 96hr), carbon sources (dextrose, fructose, glucose, maltose, lactose, sucrose, starch), nitrogen sources (ammonium nitrate, ammonium chloride, yeast extract, beef extract, peptone) on violacein production by C violaceum isolated were examined. Antibacterial activity of gram negative and gram positive organisms was done and the MIC of violacein was determined. The amount of violacein produced by C violaceum was 34.98mg/l. The production of violacein was increased with increase in temperature reaching its maximum value at 37°C. The optimum pH and incubation time for the production of violacein from the isolate were pH 6.5 and 72hr. Glucose and yeast extracts were most efficient carbon and nitrogen sources for the violacein production from C violaceum isolated. The violacein was highly sensitive to S aureus and Escherichia coli with inhibition zone of 15mm resistant to Klebsiella aerogenes and Pseudomonas aeruginosa with no inhibition zone. This study revealed that violacein has antibacterial activity against Gram positive and Gram negative organisms and provides knowledge of factors influencing the production of violacein. It also revealed the MIC of violacein and the MBC against different bacteria. The findings from this work could be of interest and suggest the need for further investigations in terms of toxicological studies and purification of active components with a view to using violacein in novel drug development.
Nematicidal Activity of Lactic Acid Bacteria against Root-Knot Nematodes
Authors: DSS Ibrahim
Published: July 2022

Root-knot nematodes are economically important obligate parasites of plant root that parasitize more than 3000 species of plant. Lactic Acid Bacteria (LAB) are well known as strong producers for wide range of organic acids that have been suggested recently to possess a remarkable lethal effect on root-knot nematodes. In the present ‘study’ 37 LAB strains were isolated from soil and agricultural wastes by using MRS medium and screened for their nematicidal activity under lab conditions. Four bacterial isolates, recorded lethal effect on second stage juveniles by more than 94%, were selected and identified by molecular method. Further, the nematicidal activity at two concentrations (i.e 50 and 10%) of the most promising ten LAB cultures was screened. The nematicidal activity of LAB was positively correlated to the concentration of their suspension cultures.2S4 (Pediococcus pentosaceus MW558270), 2S5 (Pediococcus pentosaceus MW558883), 3S1 (Pediococcus pentosaceusMW558885) and 1A3 (Pediococcus pentosaceus MW558152) isolates showed significant mortality effect by 88.42, 87.37, 81.05 and 85.96%at the low concentration (10%), respectively. In order to confirm the relationship between organic acid production by LAB and their nematicidal activity, an artificial succinic acid, lactic acid, malic acid, acetic acid, and their mixtures were tested at concentration of 1% for their ability to inhibit juvenilesvitality. The mixture of acids induced the maximum mortality effect by 100% followed by lactic acid which recorded 99.66% mortality effect. The microscopic studies and the malformation pattern of the juveniles indicating that the nematicidal activity of LAB may be derived mainly from their natural organic acids mainly lactic acid.
Role of Rhizosphere Microbiota of Plants Growing in Heavy Metal Contaminated Environments as Ecofriendly Decontamination Bio-Tools and their Role in the Context of Human Health – A Short Review
Authors: AG Khan
Published: July 2022

Air, soil and water resources of our world are contaminated by heavy metals (HMs) via agricultural, urban, industrial, mining and smelting human activities which are threatening human health causing various human health issues such as sleeping disorders, kidney damage, tubular damage in various human organs, stomach cancer, heart diseases, brain damage and various neurological disorders, lung damage, anxiety/depression, etc. Various physio-chemical and biological decontamination mechanisms and strategies are being proposed for decontamination purposes, involving habitat-adapted plants growing on such contaminated sites and their rhizosphere associated microbiota, i.e. Phyto degradations or breakdown of HMs by Nanoparticles (NPs) synthesised by plant-root tissues and their associated symbiotic microbiota including Plant Growth Promoting Microbes (PGPM) and universal and ubiquitous Arbuscular Mycorrhizal Fungi (Nano-Mycorrhizo-PhytoRemediation-NMPR). This phenomenon has recently attracted much research attention and it could be adapted for a variety of environments with no added cost or any special requirements to remediate land and water ecosystems, including indoor closed areas like high rise buildings, Gardens, and Parks, aquaria, etc. Plants growing in the HM-contaminated soil or water ecosystems and their root-associated microbiota offer an environmentally green-clean technology for air, soil and water purification and bio-decontamination measures. This short review discusses the use of plants and their root associated microbiota as a novel line of inquiry, i.e. use of ecofriendly bio-tools for bio-decontamination of heavy metal contaminated ecosystems and their role in the context of human health.