bluuebunny/crossref_metadata_2025 huggingface dataset:
Оценка влияния различных схем гипотензивной терапии на состояние эндотелиального гликокаликса системы кровообращения у пациенток с преэклампсией
Authors: Муминова Камилла Тимуровна , Зиганшина Марина Михайловна , Ходжаева Зульфия Сагдуллаевна
Published: November 2022

Преэклампсия (ПЭ) — это гетерогенный синдром, осложняющий 3 – 8 % беременностей. Из-за высокой частоты неблагоприятных краткосрочных и отдаленных исходов ПЭ для матери и плода уже многие десятилетия ведутся активные поиски предикторов, биомаркеров и лекарственных мишеней при данной патологии. Существует два фенотипа заболевания, зависящих от срока манифестации клинической симптоматики: ранняя (до 34 недель беременности) и поздняя (после 34 недель) ПЭ. Полагают, что этиология и, соответственно, патогенез этих 2 форм патологии различен, что объясняет неэффективность современных подходов к прогнозированию и профилактике заболевания. И, тем не менее, доказана роль эндотелиальной дисфункции в этиопатогенезе ПЭ (как с ранним, так и с поздним началом), инициирующим фактором которой является повреждение и «сшелушивание» эндотелиального гликокаликса (эГК) — слоя протеогликанов и гликопротеинов, выстилающего эндотелий сосудов и обращенного в их просвет. Степень деградации эГК отражает тяжесть течения заболевания. Единственным применяемым симптоматическим методом фармакологического воздействия при ПЭ является применение гипотензивных лекарственных средств (ЛС). Поскольку ранее была доказана протективная роль подобных ЛС в отношении эндотелия при ПЭ, целью нашего исследования был анализ состояния эГК у пациенток с ранним и поздним началом ПЭ, получающих либо однокомпонентную — метилдопа (допегит), либо двухкомпонентную — метилдопа (допегит) и нифедипин (кордафлекс) терапию. При раннем начале ПЭ (как при приеме одного, так и двух гипотензивных ЛС) отмечались признаки эндотелиальной дисфункции в отличие от ПЭ с поздним началом, что подтверждает различия в этиологии данных форм заболевания и свидетельствует о необходимости пересмотра существующих подходов к назначению гипотензивных ЛС в контексте исследования их «эндотелиальных» эффектов у пациенток высокого риска развития ПЭ.
Thermobar: An open-source Python3 tool for thermobarometry and hygrometry
Authors: Wieser Penny , Petrelli Maurizio , Lubbers Jordan , Wieser Eric , Ozaydin Sinan , Kent Adam , Till Christy
Published: November 2022

We present Thermobar, a new open-source Python3 package for calculating pressures, temperatures, and melt compositions from mineral and mineral-melt equilibrium. Thermobar allows users to perform calculations with >100 popular parametrizations involving liquid, olivine-liquid, olivine-spinel, pyroxene only, pyroxene-liquid, two pyroxene, feldspar-liquid, two feldspar, amphibole only, amphibole-liquid, and garnet equilibria. Thermobar is the first open-source tool which can match up all possible pairs of phases from a given region, and apply various equilibrium tests to identify pairs from which to calculate pressures and temperatures (e.g. pyroxene-liquid, two pyroxene, feldspar-liquid, two feldspar, amphibole-liquid). Thermobar also contains functions allowing users to propagate analytical errors using Monte-Carlo methods, convert pressures to depths using different crustal density profiles, plot mineral classification and mineral-melt equilibrium diagrams, calculate liquid viscosities, and convert between oxygen fugacity values, buffer positions and Fe speciation in a silicate melt. Thermobar can be downloaded using pip and extensive documentation is available at https://thermobar.readthedocs.io/.
Same World Cup, Different News Frames
Authors: Kang Hyunmee
Published: November 2022

This study examined differences in slant, deviance, and prominence in news coverage of the 1998 France and 2002 S. Korea/Japan World Cup and host countries, considering countries’ political, economic, and cultural ties as external determinants of the newsworthiness of foreign news. The main findings were that hosting the World Cup did not influence the positive image of a host country or the degree of deviance and prominence of news; U.S. journalists’ preferences for topics covered in foreign news was found in World Cup-related host country news as well as general news of host countries; political, economic, and cultural ties between host countries and the United States were reflected in the general news of host countries; and news coverage of non-Western countries was significantly different in general news. Keywords: news frames of international sporting events, deviance, 1998 and 2002 FIFA World Cup news, national images of South Korea, Japan, and France
Disruptive Strategy and Innovation Aplikasi Layanan Kesehatan Halodoc Vs Rumah sakit
Authors: novandra exel
Published: November 2022

Tenaga kesehatan atau healthcare professional adalah orang-orang yangsecara profesional memberikan pelayanan kesehatan setelah menempuh pendidikan dan pelatihan formaldalam disiplin ilmu tertentu. Tenaga kesehatan umumnya dikelompokkan menjadi berbagai profesi,misalnya dokter, dokter gigi, dokter hewan, asistendokter, apoteker dan asistennya, perawat, fisioterapis, bidan, psikolog klinis, dan sebagainya. Seorangtenaga kesehatan juga bisa merupakan seorang ahli kesehatan masyarakat. Dalam setiap bidang keahlian,para praktisi sering diklasifikasikan menurut tingkat dan spesialisasi pendidikan dan keterampilannya.Dalam cakupan yang lebih luas, tenaga kesehatan bekerja bersama-sama dengan tenaga pendukungkesehatan (allied health professions) seperti ilmuwan laboratorium medis, ahli gizi, dan para pekerjasosial lainnya. Mereka tak hanya bekerja sama di rumah sakit atau fasilitas layanan kesehatan lainnya,tetapi juga dalam pelatihan akademik, penelitian, dan urusan administrasi. Beberapa di antara merekamemberikan layanan untuk merawat dan mengobati pasien di rumahnya masing-masing.
LB10/Siwi Tyas Purbowati/ 2440104132
Authors: Purbowati Siwi Tyas
Published: November 2022

Di Indonesia, bisnis travel tradisional sudah meredup, hampir 60% pemesanan tiket transportasi dan hotel sudah menggunakan online booking melalui OTA, sepertitiket.com (Mardiana, 2017). Perkembangan terkini, keberadaan OTA yang semakin banyak menunjukkan dampak positif internet dalam sektor industri tourism. OTA merupakan salah bentuk aplikasi internet yang memberikan kemudahan pada konsumen remaja untuk melakukan perjalanan dengan memilih langsung akomodasi dan transportasi yang akan digunakan tanpa melalui jalur intermediaries yang panjang. Peran internet menyebabkan OTA menjadi jalur distribusi yang lebih efektif dibandingkan travel agent tradisional (Carroll & Siguaw, 2003; Garces et al., 2004)
PERSATUAN INDONESIA
Authors: Hona Maria Yulita Dwicecar
Published: November 2022

Mewabahnya virus Covid-19yang merupakan varian baru dengan belum diketahui cara penangannya membuaat sendi-sendi kehidupan masyarakat berubah dan bahkan banyak terjadi permasalahan sosial dalam lingkungan masyarakat munculnya perpecahan dalam masyarakat, kecumburuan sosial dan sifat individual yang hal tersebut merupakan latar belakang permasalahan di dalam penelitian ini. Penelitian ini bertujuan untuk mengetahui bagaimana peran kepala dalam membangkitkan persatuan dan kesatuan masyarakat dengan mengimplementasikan Peraturan Pemerintah Nomor 72 Pasal 14 Tahun 2005 tentang Tugas, Wewenang, Kewajiban dan Hak Kepala Desa. diketahui bahwa kepala desa sudah sangat berperan aktif dalam penanganan permaslahan terjadi yang sudah mengimplementasikan Peraturan Pemerintah Nomor 72 Pasal 14 Tahun 2005 tentang Tugas, Wewenang, Kewajiban dan Hak Kepala Desa sehingga bangkit kembali nilai-nilai persatuan dan kesatuan dalam lingkungan masyarakat melalui kegiatan gerakan sosial “Seribu Rupiah Untuk Kemanusiaan”. Sehingga dapat disimpulkan bahwa melalui peran kepala desa dalam kegiatan gerakan sosial “Seribu Rupiah Untuk Kemanusiaan” mampu membangkitkan persatuan dan kesatuan masyarakat selama masa pandemic Covid-19.
Preaching the Gospel without Ceasing: Jesus' enduring Commission to His Disciples (Matt 28,16-20) (An exegetical reflection for the Priestly Silver Jubilee of Rev. Fr. Prof. P.D. Akpunonu)
Authors: Uchenna Dim Emmmanuel
Published: November 2022

Jesus came into the word to save the world. He brought to mankind the good news of salvation. Through Jesus we have come to know God, for he is the Son of God. He was "in the beginning" with God and through him all things were made (John 1,1-3). Jesus preached the Gospel throughout his ministry on Earth. After his resurrection and before His ascension he commissioned his disciples to continue this preaching to all nations (Matt 28,16-20). The Church, right from its very beginning, has remained faithful to this commission. The Acts of the Apostles, all the letters of St. Paul and, in fact, the entire NT bear testimony to this fact. Paul's missionary journeys, during which he passed through uncountable difficulties and challenges, were undertaken for this purpose. Hence he himself emphasizes: "Woe to me if I do not proclaim the Gospel" (1 Cor 9,16). He also strongly urges Timothy to always preach the Gospel, insisting on it in season and out of season, so as to patiently convince, reproach and encourage the People of God (2 Tim 4,1-2).
Peran Website Sebagai Media Komunikasi Pemasaran Startup Digital Pada Perusahaan Quora
Authors: dewi ni putu mirah cahyani titi
Published: November 2022

Perkembangan teknologi informasi dan komunikasi kini senantiasa mengalami peningkatan pesat pada pemanfaatannya yang semakin beragam menyesuaikan dengan kegiatan-kegiatan manusia yang modern dan canggih. Website adalah salah satu media promosi terpopuler saat ini. Website memiliki jangkauan waktu dan ruang yang tak terbatas. Untuk memperoleh website sebagai media efektif dalam menyampaikan informasi, diperlukan penerapan strategi tertentu sehingga kegiatan promosi website yang dilakukan mencapai hasil yang maksimal. Salah satu perusahaan yang menggunakan website sebagai media pemasaran digital adalah Quora yang berfokus pada fiturnya yaitu "question and answer". Penelitian ini bertujuan untuk mengetahui bagaimana pemanfaatan website sebagai media komunikasi pemasaran dengan studi kasus pada website Quora. Penelitian ini menggunakan metode penelitian deskriptif. Data diperoleh dari studi dokumentasi tampilan website Quora. Hasil dari penelitian ini adalah dalam media pemasaran melalui website menunjukkan bahwa Quora memiliki enam aspek dari The 7C Framework yaitu aspek konteks, konten, komunitas, komunikasi, koneksi, dan perdagangan.
McDonalds: Analisis Inovasi Disrupsi pada Bisnis Fast Food
Authors: R Iqbal Maulana
Published: November 2022

Fast food merupakan makanan cepat saji yang sudah banyak diketahui oleh masyarakat sebagai makanan alternative dikarenakan makanan tersebut dapat dibeli dan dikonsumsi dengan cepat dan mudah.
Innovasi Disrupsi Perkembangan Perbankan dalam Era Digital
Authors: Arif Endra Athaya
Published: November 2022

Era digital merupakan era dimana semua serba mudah. Kemudahan - kemudahan tersebut sudah kita rasakan mulai dari sekarang. Seperti halnya dalam perbankan yang kita di mudahkan dengan adanya aplikasi. Aplikasi ini memudahkan kita untuk bertransaksi, pembayaran, maupun menabung. kemudahan yang kita rasakan ini menjadikan peluang juga untuk kita dalam mengembangkan bisnis yang kita punya.
Neurons Can Generate Electromagnetic Waves
Authors: sun zuodong
Published: November 2022

Based on the potassium channel "origami windmill" model, and the conservation law of cell membrane area and ion inequality equation of based on the potassium channel "origami windmill" model, and Maxwell's electromagnetic theory, it is theoretically proved that neurons can generate electromagnetic waves. The electromagnetic wave is an energy wave, never disappear. Neurons are equivalent to engineering antennas, and information between neurons can be transmitted through electromagnetic waves. The material basis for neurons to generate electromagnetic waves is the result of the exchange of cations on the inner surface of the cell membrane, especially Na+ and K+; The essence of consciousness should be electromagnetic wave. The conclusion that "neurons can generate electromagnetic waves" provides theoretical support for human beings to finally solve the mystery of the brain. At the same time, the author gives seven falsification schemes. The brain is a huge gold mine, and it is too important to crack the mystery of the brain. It should be a joint operation of "multiple arms". It should not only be the work of brain scientists, but also the participation of physicists, chemists and mathematicians.
TUGAS PKN SILA KE 3
Authors: kono Maria adolfina
Published: November 2022

Negara Republik Indonesia adalah negara hukum yang berdasarkan Pancasila dan Undang Undang Dasar 1945 yang bertujuan melindungi segenap bangsa Indonesia dan seluruh tumpah darah Indonesia dan untuk memajukan kesejahteraan umum, mencerdaskan kehidupan bangsa, dan ikut melaksanakan ketertiban dunia yang berdasarkan kemerdekaan, perdamaian abadi dan keadilan sosial. Tujuan bangsa dan Negara Republik Indonesia ini dapat dicapai salah satunya melalui tata kehidupan negara dan bangsa yang sejahtera, aman, tenteram, serta tertib, yang menjamin persamaan kedudukan warga masyarakat dalam hukum, dan yang menjamin terpeliharanya hubungan yang serasi, seimbang, serta selaras antara aparatur di bidang Tata Usaha Negara dengan para warga masyarakat.
Peraturan keberagaman
Authors: manek Saverindasel susanti
Published: November 2022

Masyarakat Indonesia sangat menjunjung tinggi persatuan sehingga rasa solidaritas tercipta dengan baik. Sebagai bukti bagaimana Kemerdekaan Republik Indonesia diperoleh dari persatuan dan perjuangan. Sehingga sampai saat ini sikap persatuan ini tetap terjaga sepanjang masa dalam lingkungan masyarakat Indonesia ini. Menciptakan persatuan bukan merupakan hal yang mudah namun bila didasarkan dengan keikhlasan maka akan terbentuk dengan baik.Terciptanya persatuan akan membuat sikap gotong royong dalam keberagaman masyarakat Indonesia dengan baik. Dengan persatuan semua persoalan yang timbul dapat diatasi secara bersama, seperti bencana alam, kerusuhan, kelaparan, pertikaian antar warga, krisis ekonomi, dan lain lain. Sikap persatuan akan membentung perbedaan dalam keberagaman masyarakat Indonesia. Jangan biarkan perbedaan yang ada menjadi penghalang keberhasilan negeri ini.Marilah kita ciptakan persatuan dalam lingkungan masyarakat majemuk ini dalam keberagaman. Marilah kita bersatu tekad menghalau para penggerogot negeri ini dengan kebersamaan. Marilah kita pertahankan negara Indonesia tercinta dengan jiwa patriotisme yang tinggi. Semoga negara Indonesia menjadi negara yang adil makmur, gemah ripah lohjinawi, aman, dan tentram.
Mengenal Inovasi Disrupsi pada Online Education : Studi Kasus edX
Authors: Putri Alda Ardelia
Published: November 2022

Pendidikan merupakan salah satu hal yang diutamakan dan penting bagi berbagaikalangan. Pendidikan sangat penting untuk menambah pengetahuan dan juga mengasahketerampilan agar dapat berguna demi masa depan. Selama ini pendidikan yang sering ditemuimerupakan pendidikan tradisional. Yang mana secara umum pusat pembelajaran secara umumberada pada guru dan menempatkan siswa sebagai objek dalam belajar. Sehingga disini guruberperan sebagai orang yang serba bisa dan juga sumber informasi belajar. Namun seiringdengan berjalannya waktu dan berkembangnya jaman, mulai muncul istilah Online Educationatau Pembelajaran Elektronik. Sistem pendidikan ini diterapkan menggunakan bantuanprogram perangkat lunak.
MAKNA PERSATUAN BAGI BANGSA INDONESIA
Authors: Kolo Maria Rosari
Published: November 2022

Negara Kebangsaan Indonesia bukan sekadar timbul karena persatuan perangai yang timbul karena persatuan nasib, tetapi lebih dari itu karena adanya persatuan antara orang dengan tanah air yang didiaminya;Persatuan Indonesia bernafaskan semangat kebangsaan yang melindungi segenap bangsa dan seluruh tumpah darah Indonesia yang senasib dan sepenagungan dalam bingkai NKRI. Persatuan Indonesia dalah sikap kebangsaan yang saling menghormati perbedaan dan keberagaman masyarakat dan bangsa Indonesia;Bangsa Indonesia mampu menempatkan persatuan, kesatuan serta kepentingan keselamatan bangsa dan negara sebagai kepentingan bersama di atas kepentingan pribadi atau golongan;Segenap warga negara Indonesia mengembangkan rasa cinta tanah air dan bangsa serta bersedia berkorban untuk kepentingan negara dan bangsa apabila diperlukan;Mengembangkan rasa kebanggaan berkebangsaan dan bertanah air Indonesia.
keadilan dalam negeri tercinta
Authors: Kolo Maria Rosari
Published: November 2022

Sila Kemanusiaan yang Adil dan Beradab dalam Pancasila. Kedua, menjelaskan konsep diskriminasi rasial dan dinamika permasalahannya di Indonesia. Ketiga, kiat-kiat atau cara mengaktualisasi Sila Kemanusiaan yang Adil dan Beradab dalam memerangi fenomena diskriminasi rasal. Metode yang dipakai dalam penelitian ini adalah deskriptif kualitatif. Objek yang diteliti adalah Sila Kemanusiaan yang Adil dan Beradab dalam Pancasila dan fenomena diskriminasi ras. Diskriminasi rasial merupakan salah satu persoalan krusial yang sampai saat ini masih membayang-bayangi kehidupan masyarakat global. Indonesia sebagai negara Pancasila pun tidak pernah luput dari masalah tersebut. Persoalan diskriminasi ras di Indonesia memiliki dinamika sejarah yang cukup panjang. Secara umum masalah tersebut berkembang melewati empat masa, yakni; pada masa kolonial (penjajahan Bangsa Belanda), masa Orde Lama, masa Orde Baru dan pada masa reformasi. Eksistensi masalah tersebut dalam kehidupan bermasyarakat, berbangsa, dan bernegara bukan hanya berimplikasi terhadap keutuhan NKRI, melainkan juga terhadap citra kemanusiaan (martabat) bangsa. Citra kemanusiaan menjadi ambruk karena manusia tidak diperlakukan secara manusiawi. Manusia tidak direspek sebagai manusia, tetapi lebih dilihat dari segi penampilan fisik, serta dinilai dari latar belakang suku, budaya, agama, dan status sosial semata. Munculnya patologi diskriminasi ras dalam tubuh kebhinekaan bangsa Indonesia sampai pada era kekinian sejatinya bukan tanpa alasan. Alasan utamanya adalah karena Sila Kemanusiaan yang Adil dan Beradab, yang memberikan dasar moral dalam kehidupan berbangsa dan bernegara, belum terkristal dalam diri (seluruh hidup) manusia Indonesia. Karena itu, upaya reinternalisasi serta reaktualisasi Sila Kemanusiaan yang Adil dan Beradab adalah sesuatu yang mutlak. Tentang hal ini, setidaknya ada delapan wujud Sila Kemanusiaan yang Adil dan Beradab yang perlu diaktualisasikan, baik secara subjektif-horizontal maupun secara objektif-vertikal .
bisonR - Bayesian Inference of Social Networks with R
Authors: Hart Jordan D. A. , Franks Daniel Wayne , Brent Lauren , Weiss Michael N.
Published: November 2022

We present a user-friendly R package for fitting BISoN models and conducting a wide variety of social network analyses. The package uses a formula-based syntax that will be familiar to R users, and a single core function for fitting edge models that we hope will be accessible to practitioners. We hope our R package will facilitate wider adoption of the BISoN framework, enable more reliable inferences, and allow more sophisticated and specialised analysis of social networks.
AN EXAMINATION OF MENTAL HEALTH LITERACY AND STIGMA AGAINST MENTAL ILLNESS USING AN ITEM RESPONSE THEORY APPROACH
Authors: Bowman Angela S. , Kim Jwa , Hamilton Gloria , Owusu Andrew , Weatherby Norman
Published: November 2022

Mental illness is a leading cause of disease burden for college age individuals and impacts an estimated 43 million Americans annually. The individual burden of mental illness causes high physical morbidity and mortality that leads to a dramatically shortened lifespan. Mental illness is highly treatable, and early intervention leads to an improved long-term outcome. Regardless of level of disability, people displaying symptoms of mental illness are more harshly stigmatized than those with other non-mental health ailments. The latter stigmatization results in years long delay in mental health help-seeking.Existing evidence indicates that health literacy is vital to maintaining good physical health. However, the knowledge and skills that facilitate one’s ability to prevent, recognize, and manage mental health related issues has not been incorporated into traditional definitions of health literacy. Mental health literacy programming has been hypothesized to improve delays in mental health help-seeking through improved knowledge and awareness that results in reduced stigma against mental illness. The evidence base supporting this hypothesis is lacking mainly due to the need for theory-based psychometrically sound instruments that allow for reliable and valid measurement of mental health literacy.The appropriate assessment of mental health literacy is critical to reducing the burden of mental illness stigma. Thus, this study uses advanced statistical and psychometric analyses, including item response theory, to examine items of a recently developed scale purporting to measure mental health literacy. Major scale revisions are elucidated, and using theory-based test construction practices, a new mental health literacy scale is proposed.The psychometric properties of the new scale are discussed, as is the extent to which mental health literacy is related to enacted mental illness stigma. The use of the new mental health literacy scale as part of evidenced-based interventions to improve mental health literacy should help lessen the burden of stigma against people with mental health problems.
Molecular Dynamics Simulation of Wetted Contacts: Fundamental Phenomena and Fluid Properties
Authors: Lautenschlaeger Martin
Published: November 2022

Wetted contacts play an important role in many fields. A prominent example in engineering is the lubricated contact between tool and workpiece in machining processes with cutting liquids. In such contacts, highly dynamic processes occur in the fluid at small length scales under extreme conditions regarding temperature, pressure, and shear. Experimental studies of these phenomena are generally not feasible. Thus, only little information on the actual processes in the contact zone is available. A tractable route for obtaining such information is molecular dynamics (MD) simulation. As input for these simulations, only a potential model that describes the interactions on the atomistic scale, is needed. On that basis also complex processes can be predicted. In the present work, a simple model potential was used, i.e. the Lennard-Jones truncated and shifted potential (LJTS), which was parameterized to describe the solids, the fluid, and their interactions. A novel method for determining fluid properties with non-equilibrium MD simulations was developed, which yields thermal, caloric and transport propertiesin a single simulation run. It can also be used for studying the influence of shear on these properties. With the new method, a comprehensive study of properties of the LJTS fluid was carried out. Furthermore, it was investigated how these fluid properties change near the solid-fluid interface and how these changes affect the conductive heat transfer between the solid and the fluid. Finally, a nanotribological process was studied, in which all these phenomena occur simultaneously.
Clinico- radiological profile of genetically proven Complicated Hereditary Spastic Paraparesis: A case series
Authors: Ranjan Abhay , Kumar Abhishek , Sinha Neetu , Mudassir Sanaullah
Published: November 2022

Complicated Hereditary Spastic Paraparesis (HSP) is a group of heterogenous neurodegenerative disease characterized by progressive spastic paraparesis with additional features like cognitive impairment, seizures, movement disorders, visual loss, deafness, peripheral neuropathy, and pes cavus. There have been few case series reported in literature from India. We herein report four cases of complicated HSP. Four (three females and 1 male) patients of genetically confirmed HSP with a mean age of onset 10.5 years were recruited. There was mean delay of 8 years in reaching diagnosis. MRI brain showed thinning of corpus callosum in three patients and Ear of lynx sign in two patients. Next Generation Clinical Exome Sequencing confirmed mutations in SPG11 gene in three patients and SLC2A1 in one patient. SPG11 gene mutations were the most frequent genetic abnormality with SLC2A1 gene mutation in single patient. Genetically confirmed diagnosis helps in prognostication and genetic counselling.
Giant Occipital Meningoencephaloceles: Challenges in Management and Our Experience
Authors: Gautam Sachinda Nand , Singhal Manoj , Panchariya Piyush Kumar , Acharya Jigmisha
Published: November 2022

Introduction: Giant encephalocele are encephalocele more than the size of head from which it arises. They pose a management challenge in view of risk of associated anomaly, challenges in anaesthesia and surgical management. There is no literature available from peripheral tertiary care centres from India apart from few case reports.
Methods: This case series comprises of seven cases operated at our institute from 2014 to 2021. After routine clinical examination, patients subjected to recommended radiological investigations. Patients were anaesthetised with standard protocol with intubation in lateral or supine position with head hanging at edge of table and supported at table. Surgery carried out in lateral position with complete excision of sac with CSF diversion if pre existing hydrocephalus was present.
Results: Out of seven cases, 3 were males and four female with age range from 12 days to 14 Mo. All patients were anaesthetised with standard protocol and had excision of sac with CSF diversion if required with satisfactory outcome in post operative phase and follow up. No death was recorded.
Conclusion: With careful assessment and all recommended investigation with standard practice of anaesthesia and surgery, acceptable outcomes can be expected. Emphasis should be laid for good antenatal folate supplementation and possible antenatal diagnosis of meningoencephaloceles.
Predictors of Outcome of Aneurysmal Subarachnoid hemorrhage
Authors: Bishokarma Suresh , Shrestha Shikher , Rijal Suman , Karki Anjali , Shrestha Sunita , Thulung Suraj
Published: November 2022

Introduction: Aneurysmal Subarachnoid Hemorrhage (aSAH) is a devastating condition with high mortality and morbidity. Significant factors influencing the prognosis of aneurysmal subarachnoid hemorrhage (SAH) include the severity at presentation of the disease and delayed cerebral ischemia (DCI).

Methods: This is a prospective study conducted in Upendra Devkota Memorial National Institute of Neurological and Allied Sciences (UDM-NINAS), Bansbari, Kathmandu, Nepal among patients who underwent clipping of aneurysm for subarachnoid hemorrhage. Various clinical and radiological prognostic factors were registered on admission and during the intensive care stay. Outcome was recorded. GOS>3 was considered good outcome and GOS ≤3 was considered poor outcome.

Results: Seventy-two patients with ruptured aneurysm were surgically clipped. Good outcome was observed in 51 (70.83%) patients while poor outcome was seen among 21 (29.17%) patients including death among 16 (22.2%) patients. In univariate analysis, WFNS>2, Fisher grade >2, EVD placement for hydrocephalus and delayed cerebral ischemia (DCI) were found to have statistically significant in poor outcome. On Multivariate logistic regression model showed delayed cerebral ischemia was statistically significant predictor of poor outcome at p= 0.032 (OR= 7.34; 95% CI=1.280 to 17.702).

Conclusion: WFNS >2, Fisher grade>2, EVD placement and DCI were found to have statistical significance in poor outcome while only DCI was an independent predictor of poor outcome following aneurysmal Subarachnoid Hemorrhage (aSAH).
Telemedicine for Neurological Consultations in Nepal
Authors: Gajurel Bikram , Tamrakar Parishma
Published: November 2022

Introduction: Telemedicine is a method of using a variety of telecommunication techniques to evaluate patients. This research was carried out to study the clinical and demographic characteristics of the patients who sought neurological care via telemedicine during the first and second waves of the coronavirus disease 2019 pandemic.

Methods and Materials: It is a retrospective study based on patients’ records. Patients were consulted via Viber, WhatsApp, Facebook Messenger and telehealth facility of Danphe Care. The data were entered into and analyzed by using the Statistical Package for the Social Sciences version 26.

Results: A total of 197 patients were examined. Viber was the most common tool used (n=109, 55.3%). One hundred and twenty-two patients (61.9%) were from outside the Kathmandu Valley. Majority of the patients (n=155, 78.7%) did not come across any technical disturbances during the consultation. Cerebrovascular diseases were the most common diseases evaluated followed by headache disorders and seizures. One hundred and thirty-seven patients (69.5%) did not require further investigations, 179 (90.9%) did not require in-person evaluations and 142 (72.1%) did not require referral to other specialists for further evaluation. Majority (54.3%) of the patients became better at follow-up.  All patients who became better had at least one follow-up compared to 82.2% of the combined who remained static or had unknown status of their health in follow up (p = <0.001).

Conclusion: Telemedicine is a useful tool to evaluate various neurological disorders. Even though most of the patients did not require investigations, referrals and in-person visits, majority of the patients improved. Patients who have at least one follow-up became better compared to patients who did not have any follow-ups.
Fourth Industrial Revolution and the Future of Neurosurgery
Authors: Sharma Mohan Raj , Sharma Meghraj
Published: November 2022

Arguably, neurosurgery is the second oldest profession although it only evolved as a distinct field of surgery in the 20th century. During the last seven decades, the advent of the operating microscope, intraoperative neuro monitoring, neurointensive care, neuronavigation, and the evolution of minimally invasive and endovascular techniques have changed the landscape of neurosurgery. This editorial intends to highlight the importance of the fourth industrial revolution (Industry 4.0), its components, and how they have the prospect of being integrated into the practice of medicine, especially neurosurgery.
China en África: Objetivos, instrumentos e implicaciones estratégicas
Authors:   Universidad Loyola, Andalucía, Delage Fernando
Published: November 2022

Desde el fin de la Guerra Fría, cuatro grandes prioridades definieron la estrategia de la República Popular China hacia África: el acceso a recursos naturales y materias primas; la consecución de mercados para sus exportaciones de manufacturas; la obtención de apoyo a sus objetivos políticos; y la consolidación de un estatus como líder del mundo en desarrollo. A partir de la primera década del siglo XXI China se ha convertido asimismo en un importante socio financiero y en impulsor del desarrollo de infraestructuras en el continente, a la vez que ha adquirido una creciente presencia militar. La relación multidimensional construida por la China de Xi Jinping con África forma parte integral de su estrategia de ascenso global, con implicaciones económicas y geopolíticas que han atraído la atención de las restantes potencias
Hacia las mÃ©tricas de contexto: clasificaciÃ³n de citas en Web of Science
Authors: OrduÃ±a-Malea Enrique
Published: November 2022

El objetivo de esta nota es describir la nueva funcionalidad de clasificaciÃ³n de citas por contexto proporcionada por Web of Science (WoS), en la que las citas recibidas por un trabajo se clasifican en cinco categorÃ­as (Background, Basis, Support, Differ, Discuss). Con el fin de testear las prestaciones de la funcionalidad se han llevado a cabo dos casos de estudio. Por un lado, una revista (Profesional de la informaciÃ³n; 1,604 publicaciones) y, por otro lado, un autor (Loet Leydesdorff; 341 publicaciones). Ambos casos reflejan la todavÃ­a baja cobertura de citas clasificadas (inferior al 6%) que limitan el uso de esta funcionalidad actualmente. Finalmente se discuten algunos de los interrogantes que se abren con el uso de estas mÃ©tricas de contexto, tales como la precisiÃ³n, comprensiÃ³n, simplificaciÃ³n, representatividad, comparabilidad, idioma, agregaciÃ³n, uso evaluativo, efectos y extrapolaciÃ³n.
Kontribusi Kekuatan Otot Lengan terhadap Hasil Tolak Pelurusiswa Smp Negeri 07 Rambah Samo Kabupaten Rokan Hulu
Authors: Mulyadi Hendri
Published: November 2022

The problem of this research is the low ability of the students to shoot the results of SMP Negeri 07 Rambah Samo Rokan Hulu Regency which is influenced by the weak strength of the arm muscles in repelling bullets. The purpose of this study was to determine the contribution of arm muscle strength to the shot put results of students at SMP Negeri 07 Rambah Samo, Rokan Hulu Regency.This type of research is a correlation that looks at the extent of the contribution of arm muscle strength to the results of the shot. The population of this study were 29 students of SMP Negeri 07 Rambah Samo Rokan Hulu Regency. The sample was taken using total sampling technique. The research instrument for arm muscle strength was the push up test. As for the results of the shot put down, the measurement is done by carrying out the shot put test. The analysis technique used is manual product moment correlation.The results showed, 1) arm muscle strength was categorized as good with a value of 56.31%, 2) the results of the shot were categorized as good with a value of 43.69%, 3) data analysis showed that the value of rxy (rhitung) was 0.573 with r table 0.532 then the r count is obtained from the r table, so there is a contribution of 33%. There is a contribution between arm muscle strength to the results of the shot at SMP Negeri 7 Rambah Samo Rokan Hulu Regency.

Keywords: arm muscle strength, shot put results
Kompetensi Guru Pendidikan Jasmani, Olahraga dan Kesehatan di Sekolah Dasar Negeri Sekecamatan Luas, Kabupaten Kaur, Provinsi Bengkulu
Authors: Syaputra Roni
Published: November 2022

This type of research is mixed method (quantitative-qualitative) by using sequential explanatory design or combination model research. The population in this study is all teachers of physical education, sports and health in public schools sekecamatan wide. The sampling technique used a saturated sampling technique with a sample size of 7 people and an informant consisting of supervisors, principals, physical education teachers, sports and health, teachers and students. Data analysis techniques that researchers use in the early stages are (quantitative method) with Likert scale. Then in the second stage is (qualitative method) deangan component analysis data flow model.The results showed that most of the competence of teachers of Physical Education, Sport and Health at State Elementary School Sekecamatan Luas, Kaur district, Bengkulu Province included in very good category with percentage (96.49%) this shows that most teachers of Physical Education, Sports And Health at State Elementary School of Sekecamatan Luas have been able to carry out 4 main tasks of teachers with details in every aspect that is: 1) Pedagogic competence with percentage (82.29%) including very good category in understanding the learners more deeply, designing, implementing and evaluating Learning and developing the potential of learners, 2) Personality competence with percentage (87.86%) including the category of excellent in acting in accordance with religious, legal, social norms, displaying themselves as an honest person, noble, steady, stable, Wise and authoritative, 3) Social competence with percentage (93.33%) is categorized as excellent in being inclusive, acting objectively, communicating effectively, empathetically and courteously with fellow educators, education personnel, parents and society, (4) Professional competence with percentage (77.52%) including good category in mastering learning materials widely And deep.

 

Keywords : Teacher Competence Physical Education, Sport And Health
Penerapan Pendekatan Tutorial pada Pembelajaran Servis Atas Bola Voli di Smp Negeri 13 Lubuklinggau
Authors: Suhdy Muhammad , Supriyadi Muhammad
Published: November 2022

The tutorial approach is basically the same as the guidance approach, which aims to provide assistance to students or students in order to achieve optimal learning outcomes. The purpose of this study was to determine the improvement of the top service techniques in volleyball games by using a tutorial approach at SMP Negeri 13 Lubuklinggau.The method used in this study was Classroom Action Research (CAR) with the subject of this research being conducted at Grade VIII students of SMP Negeri 13 Lubuklinggau in the 2018/2019 academic year, totaling 36 students consisting of 18 male students and 18 female students of class V totaling 32 students. Data collection techniques using II (two) cycles. After the data is obtained, the data is processed using strugess rules.Based on the results of calculations and analysis of the data that has been described, it can be stated that the mastery of basic technical services for volleyball before and after the implementation of the first cycle has increased significantly, this can be seen from the average percentage of indicator I (throw up) before the implementation of the first cycle of 59.82% was classified as sufficient, in the first cycle of 75.56% was classified as good and in the second cycle of 86.48% was classified as very good; indicator II (hitting the ball) before the implementation of the first cycle of 60.22% was classified as sufficient, in the first cycle of 73.33% was classified as sufficient and in the second cycle of 85.58% was classified as very good; and indicator III (follow through) before the implementation of the first cycle of 60.28% is quite sufficient, in the first cycle of 73.33% is sufficient and in the second cycle of 85% is quite good.

 

Keywords: top service, Tutorial Approach
Perbedaan Kesegaran Jasmani antara Siswa yang Berekonomi Tinggi dengan Siswa Berekonomi Rendah di SMA Negeri 5 Lubuklinggau
Authors: Supriyadi Muhammad , Suhdy Muhammad
Published: November 2022

he purpose of this study was to obtain information about the differences in physical fitness between students with high economics and students with low economics at SMA Negeri 5 Lubuklinggau. This type of research is Ex Pos Facto Research, that a study was conducted to examine events that had occurred and then look at backward to know the factors that can cause this incident. The population of this study were high-economic students and low-economic students, amounting to 50 students. The sample collection technique is total sampling. Which is total sampling is said to be saturated (complete) if the entire population is sampled. The tool used to collect data is the Indonesian physical fitness test, then analyzed with the statistical t test technique. The results obtained from this study are as follows the difference in physical fitness between high-economic students and low-economic students that is equal to 1.87 and ttable 1.68. So the conclusion there are differences in the level of physical fitness between students with low economics and students with high economics at SMA Negeri 5 Lubuklinggau

 Keywords: Differences in Physical Freshness
Hubungan Vertical Jump dengan Jump Shoot Pada Permainan Bola Basket Grup Megic Kid Lubuklinggau
Authors: Winata Bimo Sepra
Published: November 2022

This study aims to determine whether there is a relationship between vertical jump and jump shot in the basketball game of the magic kid Lubuk linggau group. The research method used is descriptive, and the type of research is correlation analysis. The sample in this study was the Magic Kid Lubuk linggau Putra group, with as many as10 people. The data collection technique in this study was a test. The data analysis technique used the following steps: normality, homogeneity, and correlation test. The instruments used in this study were the vertical jump test and the jump shot into the ring for one minute. The results of statistic analysis from multiple correlation analysis obtained dan F-count of 0.1262, with a significance level of 5%, an F-table of 0.632 was obtained. It turns out that F-count 0.1262 is smaller than F-table 0.632, meaning no significant relationship between vertical jump and jump shoot in basketball games. The results showed no significant relationship between vertical jump and jumped shot in the basketball game of theme Magic Kid Lubuklinggau group 

Keywords: Basket Ball, Jump Shoot, Relationship, Vertical Jump,
Efektivitas Latihan Senam Jantung Sehat untuk Menurunkan Kadar Lemak pada Ibu-Ibu PKK Desa Sukowarno Kabupaten Musi Rawas
Authors: Pujiati Pujiati , Suhdy Muhammad , Remora. Hengky
Published: November 2022

This study aims to determine the decrease in fat levels in PKK women in Sukowarno Village after being given a Healthy Heart Gymnastics exercise. The research method used was quasi-experimental. The data collection technique in this study used a skinfold calipers body fat percentage test. Data analysis technique with normality test. Based on the survey results, the magnitude of t count is 12.63 and t table 2.056 with a significant 5% (α = 0.05) with degrees of freedom dk = n-1 where n is the number of student data as many as 27 mothers. Suppose the value of t count > t table. Then the hypothesis is accepted so that the average results of fat levels in PKK women in Sukowarno village after being given healthy heart exercise are less than the post-test average value. In conclusion, healthy heart exercise effectively reduces fat levels in PKK women in Sukowarno village, Musi Rawas district.

Keywords: Decrease, fat content,  healthy heart exercise,
Proses Pembayaran Uang Japuik Dan Uang Ilang Dalam Sistem Perkawinan Di Nagari Manggopoh Kabupaten Agam
Authors: Delmiati Susi
Published: November 2022

The purpose of this study was to determine the process of paying japuik and moneylang money in the marriage system in Nagari Manggopoh, Agam Regency. This type of research is a qualitative research with a descriptive type. The research informants were determined by purposive sampling. The results of this study indicate that the process of paying japuik money includes: a) Determination of the nominal value of japuik money by both parties during maresek / maanta asok, b) Determination of the time of payment of japuik money, which is when picking up The bride and groom at night after the beretong event, c) The female mother hands over the japuik money to the male mamak. Meanwhile, the process of paying lost money includes: a) Determination of the nominal value of lost money by both parties during maresek / maanta asok, b) Determination of the time for payment of lost money, namely before the wedding party, c) Handover money lost between the parents of both parties, namely before the wedding party. The conclusion is that there are similarities and differences in the process of determining japuik money and money lost, namely both determining the nominal money, the difference in the timing of funding before and during the wedding, and the difference in the handover.

Keywords: Jengik money and lost money
Pengembangan Nilai-Nilai Demokratis Mahasiswa Melalui Pendidikan Kewarganegaraan
Authors: Adisel Adisel , Suryati Suryati
Published: November 2022

ABSTRACT

The purpose of this study was to determine the development of democratic values in students through civic education. This study uses a descriptive method with a qualitative approach. The results of the study show that the democratic values of students through civic education are one of them having tolerance, freedom of expression, respect for differences of opinion, upholding and human dignity. The conclusion of this research is that students who understand civic education will be able to practice democratic values in society.

 

Keywords: Citizenship Education, Democratic Values, Students.
Dampak Globalisasi dalam Proses Pembelajaran Pendidikan Pancasila dan Kewarganegaraan
Authors: Syavanny Febria , BP Silvia Anggreni , Kurnia Ade
Published: November 2022

ABSTRACT

The purpose of the study was to determine the effect of globalization in the teaching and learning process, both positive and negative impacts and to determine the efforts of teachers in overcoming the negative impacts of globalization in the teaching and learning process on Pancasila and citizenship education in class XI SMKN 3 Payakumbuh. The research method uses a qualitative descriptive method. The results of the study show that the impact of globalization in the learning process of Pancasila and Civics education includes: (A) The positive impacts of globalization: 1) The increase in science and technology can enrich learning resources, 2) The values ​​and attitudes of students change in a positive direction, 3) The level of student life becomes more good, 4) The rules in learning are getting better, 5) Enriching culture in the learning process. (B) Negative impacts of globalization: 1) Students' lifestyles become consumptive and westernized, 2) Attitudes become individualistic, 4) Social inequality between students, 5) Rules or rules in the learning process, 6) Cultural fields or habits in the learning process . The conclusions of the study indicate the efforts of teachers in overcoming the negative impacts of globalization in the learning process of Pancasila and Citizenship Education, namely: (1) Overcoming the negative impacts of globalization by teachers, (2) Fostering the spirit of nationalism, (3) Practice of Pancasila values, (4) Practice of teachings religion, (5) Formation of student character.

 

Keywords : Globalization, Pancasila Education Learning and Citizenship
Antimicrobial and Antibiofilm Activities of Synthetic Lawsone Derivatives Containing N-Substituted 1,2,3-Triazole Against Dental Caries Pathogens
Authors: Ratti Pichayaporn , Manuschai Jutharat , Kara Jiraporn , Naorungroj Supawadee , Lomlim Luelak
Published: November 2022

Objective: Presently, one of the most common oral diseases is dental caries, which is a biofilm-mediated disease. Lawsone methyl ether (LME) has shown promising antibacterial activity due to its 1,4-napthoquinone structure. Recently, a 1,2,3-triazole scaffold has been used in the structural modification of potential antimicrobial agents. To develop novel anticaries agents, the structure modification of 1,4-napthoquinone with N-substituted 1,2,3-triazole, therefore, may be a candidate. Material and Methods: LME was used as a lead compound, and three new lawsone derivatives were prepared by two-step reactions. Their antimicrobial effects against three dental caries pathogens; including S. mutans, L. casei, and A. naeslundii were investigated, using the microdilution technique (0.78-100 μg/mL). A growth curve assay was performed to assess the effects of compounds on the growth kinetics of bacteria. Moreover, the effect of synthetic lawsone derivatives on the biofilm formation of S. mutans was also evaluated by crystal violet assay. Results: Overall, S. mutans was most sensitive to lawsone derivatives (minimum inhibitory concentration (MIC)=1.56- 50 μg/mL), followed by A. naeslundii and L. casei: corresponding to their growth curves. Lawsone derivatives, at the concentration of 1/2 MIC and 1/4 MIC, inhibited 12-hour S. mutans biofilm formation by 86.0-98.0%. The inhibitory effect decreased with decreasing concentrations and increasing incubation times. Conclusion: Synthetic lawsone derivatives have an inhibitory effect on the growth of three tested cariogenic bacteria, and the biofilm formation of S. mutans. The compounds exhibited anti-cariogenic bacterial strains and satisfying antibiofilm formation effects on S. mutans.