bluuebunny/crossref_metadata_2025 huggingface dataset:
Central nervous system involvement at initial diagnosis of extranodal NK/T-cell lymphoma: a retrospective study of a consecutive 12-year case series
Authors: Wu Wanchun , Ren Kexin , Li Na , Luo Qian , Zhou Huijie , Hai Tao , Zou Liqun
Published: May 2022

Purpose patients with central nervous system (CNS) involvement at initial diagnosis of Extranodal NK-T-cell lymphoma (ENKTL) are exceedingly rare, and the clinicopathologic features of CNS involvement have not been well characterized.Methods We reviewed 662 patients with ENKTL from August 2008 to September 2019. Their clinical and pathological features, treatments, and survival outcomes were analyzed. Results The median follow-up time was 72 months. Nine of 662 (1.4%) patients were diagnosed with CNS involvement. Among them, the median age was 37 years, and seven patients were male. All patients had positive EBV-DNA, and three patients were asymptomatic at the time of diagnosis with CNS involvement. Common extranodal involved sites included bone, paranasal sinuses, breast, kidney, adrenal gland and bone marrow. All patients were positive for cytoplasmic CD3ε, cytotoxic granule proteins, and EBER and negative for CD20. All patients received intrathecal chemotherapy and at least one cycle of systemic chemotherapy. Seven patients had died and two were still alive by the last follow-up. The median overall survival (OS) in patients with CNS involvement at initial diagnosis of ENKTL was 9 months, and the 1-year OS was 44.4%. Five patients achieved a complete response after asparaginase-based chemotherapy; two were still alive, one died of systemic progression, one died of ENKTL-associated hemophagocytic syndrome, and one died of treatment-related infections.Conclusion CNS involvement at initial diagnosis of ENKTL is extremely rare with poor prognosis. There is no standard treatment, and asparaginase-based chemotherapy combined with intrathecal chemotherapy might yield good efficacy.
Impact of appendectomy with Ladd procedure for midgut volvulus
Authors: Yanagida Yoshitsugu , Kawashima Hiroshi , Ishimaru Tetsuya , Hattori Kengo , Oiki Hironobu , Iguchi Masafumi , Miyake Kazue , Fujishiro Jun
Published: May 2022

Purpose: The Ladd procedure is the standard surgical technique for midgut volvulus with which a concurrent appendectomy is often performed to prevent diagnostic errors of appendicitis later in life. However, its effect on the Ladd procedure remains unclear. Here we assessed the impact of concurrent appendectomy on the Ladd procedure.Methods: The medical records of patients who underwent surgery for midgut volvulus with malrotation in 2000–2020 were reviewed. The patients were divided into groups with or without appendectomy for comparison of their characteristics and surgical outcomes.Results: Seventy patients were evaluated, among whom appendectomy was performed in eight by surgeon preference. Patient characteristics, operative time, blood loss, length of hospital stay, and volvulus recurrence rate did not differ significantly between groups. There were no cases of appendicitis. Bowel obstruction occurred in four cases (50%) in the appendectomy group (one required surgical intervention) versus six cases (9.7%) in the without appendectomy group (p<0.05). Conclusion: In our study, bowel obstruction was more common among patients who underwent appendectomy with the Ladd procedure, suggesting that concomitant appendectomy might increase the risk of postoperative bowel obstruction due to unnecessary adhesions requiring surgical intervention.
Psoas Muscle Loss During Treatment Is a Negative Predictive Factor In Gastric Cancer Patients
Authors: Öztürk Hüseyin Furkan , Arslan Suheyla Aytaç , İnan Gonca Altınışık , Aral İpek Pınar , Açıkgöz Sedef Gökhan , Beyaz Havva , Tezcan Yılmaz
Published: May 2022

Purpose: Our aim in this study is to examine the changes in the psoas muscle during the gastric cancer treatment process and to evaluate the effects on prognosis.Methods:Twenty-eight gastric cancer patients underwent curative surgery and chemoradiotherapy were analyzed. Changes were noted by calculating the psoas muscle areas before and after the cancer treatment. Patients were classified as high Δ and low Δ according to median change. The effect of muscle loss on progression-free and overall survival was examined using the logistic regression model.Results:Psoas muscle loss was observed in all patients during the treatment. While the median psoas muscle area before treatment was 14.5 cm2, it was calculated to 11.8 cm2 after treatment (p = .0).In the high delta group with excessive muscle loss, 3-year progression-free survival was 38%, compared with 80% in the low delta group (p=0.07). The 3-year overall survival was found to be 42% in the high delta group, while it was 84% ​​in the group with less muscle loss (p=0.05). Conclusion: Psoas muscle loss is a negative predictive factor in gastric cancer patients undergoing surgery and chemoradiotherapy. Nutritional assessment and support during the treatment process may play a role in survival.
Primary gastric lymphoma and spontaneous remission associated with co-infection of COVID-19 and undefined typical bacterial agent.
Authors: Kurmanova Gaukhar , Bossatbekov Yerkebulan , Alimanova Zhanna , Tankayeva Sholpan , Bugibaeva Akbota , Sarawata Abhishek , Singh Kajal , Abbas Fuza Adhur Manhuvalappa , Singh Neetu
Published: May 2022

Background: A case report underlines a clinical experience of a patient with primary gastric lymphoma disease. The article demonstrates reduction of the lymphoproliferative disorder to the spontaneous remission, after community-acquired pneumonia with co-infection of COVID-19, and undefined typical bacterial agent. A positive response has gone through a period of COVID-19 condition and appeared ongoing the standard antibacterial and basic symptomatically treatment. Case presentation: A 65-years-old woman was admitted by ambulance to the emergency department with sever condition. In time of hospitalization, the patient has diagnosed with ulcer form of primary gastric lymphoma with signs of ongoing capillary bleeding, thrombocytopenic syndrome, normochromic anaemia, diabetes militias type 2 with complication of hypoglycaemic condition associated with metformin, and chronic bronchitis. The data laboratory and instrumental investigations confirmed the condition. Conclusion: The article underlines extremely positive response up to disappearing of ulcer form of primary gastric lymphoproliferative disorder. The condition associated with anti-tumor effect of highly cytokines production because of COVID-19 and undefined typical bacterial agent.
Determination of Isocitrate Dehydrogenase (IDH1) mutation in laryngeal squamous cell carcinoma specimens
Authors: Shayanfar Nasrin , Zare-Mirzaie Ali , Mohammadpour Mahsa , Jafari Ensieh , Mehrtash Amirhosein , Emtiazi Nikoo , Tajik Fatemeh
Published: May 2022

Introduction: Laryngeal squamous cell carcinoma (LSCC) is a significant cause of mortality and morbidity among cancers. To date, no tools have been identified to predict the evolution of this cancer. There is an interest in recognizing new biomarkers that can help in the early detection and prediction of the clinical outcome of this cancer. Therefore, the present study evaluates the Isocitrate Dehydrogenase 1 (IDH1) mutation in LSCC patients.Methods: In this study, 50 patients with LSCC were studied. Immunohistochemistry was used to assess the tissue expression of IDH1. In samples reported negative or poor positive in IHC staining, gene sequencing using the PCR technique was used to confirm the diagnosis. The relationship between IDH1 mutation and tumor differentiation, pathological tumor stage, lymph node involvement, lymphovascular and perineural involvement, tumor size, age, and sex of the patient were evaluated.Results: The mean age of patients was 61 ± 8.46 years, of which 98% were male. The frequency of IDH1 mutation was 78%. The relationship between the pathological stage and lymphovascular invasion status of the tumor and IDH1 status was not statistically significant. In contrast, the relationship between the degree of differentiation, lymphatic involvement, perineural invasion status, and IDH1 status showed a statistically significant correlation (p < 0.05).Conclusion: This study showed a high frequency of IDH1 mutation in patients with LSCC. The IDH1 mutation was also associated with more aggressive tumor behavior and perineural involvement. These findings can help refine potential treatment and monitoring strategies in LSCC patients.
Blood glucose changes in general and spinal anesthesia
Authors: Al-Fawaris Ma'moun , Al-jaser Youssef , Kahal Fares , Torbey André , Rakmani Najwa
Published: May 2022

Background:
Medical literature describes how several metabolic and hormonal changes occur while undergoing different kinds of Anesthesia. This study aims to compare the effects of general and spinal anesthesia on blood glucose.
Methods:
This cross-sectional study was conducted on 254 patients from Al-Zahrawi Hospital. The patients were divided into three groups: patients with diabetes - patients without diabetes - patients with gestational diabetes. Blood glucose levels were measured before surgery and in the first and second hours after surgery, for patients undergoing both general and spinal anesthesia.
Results:
There were no statistically significant differences in the average blood glucose levels before and after surgery in patients with diabetes undergoing the two types of anesthesia: general anesthesia - spinal anesthesia. There were no statistically significant differences in the average blood glucose levels before and after surgery in non-diabetic patients, undergoing the two types of anesthesia: general anesthesia - spinal anesthesia. There were no statistically significant differences in the average blood glucose before and after surgery in patients with gestational diabetes, according to the two types of anesthesia: general anesthesia - spinal anesthesia.
Conclusion:
There are no clear differences between general and spinal anesthesia in affecting the levels of blood glucose. It is reasonable to suggest that blood glucose levels should be monitored during surgery in patients undergoing general or spinal anesthesia and during the 6, 12, and 24 postoperative hours.
Innovative SMEs Collaborating with Others in Europe
Authors: Leogrande Angelo , Costantiello Alberto , Laureti Lucio , Matarrese Marco
Published: May 2022

The following article investigates the determinants that lead innovative SMEs to collaborate. Data from 36 European countries is analyzed using Panel Data with Fixed Effects, Panel Data with Random Effects, Pooled OLS, WLS and Dynamic Panel models. The analysis shows that the ability of innovative SMEs to collaborate is positively associated with the following variables: "Linkages", "Share High and Medium high-tech manufacturing", "Finance and Support", "Broadband Penetration", "Non-R&D Innovation Expenditure" and negatively to the following variables: "New Doctorate graduates", "Venture Capital", "Foreign Controlled Enterprises Share of Value Added", "Public-Private Co-Publications", "Population Size", "Private co-funding of Public R&D expenditures". A clustering with k-Means algorithm optimized by the Silhouette coefficient was then performed and four clusters were found. A network analysis was then carried out and the result shows the presence of three composite structures of links between some European countries. Furthermore, a comparison was made between eight different predictive machine learning algorithms and the result shows that the Random Forest Regression algorithm performs better and predicts a reduction in the ability of innovative SMEs to collaborate equal to an average of 4.4%. Later a further comparison is made with augmented data. The results confirm that the best predictive algorithm is Random Forest Regression, the statistical errors of the prediction decrease on average by 73.5%, and the ability of innovative SMEs to collaborate is predicted to growth by 9.2%.
Mathematics Of Uncertainty For Quantum Computing
Authors: Thakur Usama
Published: May 2022

Quantum Mechanics and Computation has a major problem called
the measurement problem. This has given physicists a very hard
time over the years when I first looked into the problem my approach was
simple find a new number system that can go with the uncertainty of a
Quantum particle the paper deals with the mathematics of uncertainty
which has solved 2 millenium prize problems [4], [5] and quantum mea-
surement problem very efficiently. We divide chaos into two parts low
chaos and high chaos then we find the desired value [18] inside the inter-
section of both. This helps us find something in a ℵ3 >>> ∞ this takes
the problems around us to the next level if we are able to control a chaos
then we can achieve pretty much anything.
Determination of Active Vitamin D Levels, Synthesis, Demand, and Utilization
Authors: Maloney Sean Robert
Published: May 2022

Measurement of plasma (serum) 25(OH)D3, levels, (the precursor of active vitamin D) is the current method of evaluating vitamin D status. The measurement of active vitamin D, 1,25(OH) 2 D 3 and its precursor, 25(OH)D 3 , in the serum does not always reflect the overall active vitamin D synthesis and utilization by the body. This may be especially true during periods of increased demand for this hormone. Active vitamin D synthesis and degradation can occur simultaneously and is often entirely an intracellular process. The process whereby much of active vitamin D is synthesized and degraded and how it is transported out of the cell and body is presented. A method of determining active vitamin D levels, synthesis, degradation, and utilization is also presented based on the measurement of the end metabolites of active vitamin D and of its precursor vitamin D.

Unlike other vitamins, active vitamin D is a hormone acting on many receptor sites in the body and it is an essential modulator of the immune system. The vitamin D hormone plays an active role in the initial suppression of invading microbials including viruses and in subduing the body’s inflammatory response to acute viral infections and reactivation of latent viruses. The conversion of precursor vitamin D supplements to active vitamin D may be hindered in individuals with elevated body mass Index (BMI) or percent body fat when initial stores of vitamin D precursors are low and demand for active vitamin D increases suddenly such as during acute systemic infections, trauma, or other physiological stressors.

In this paper, a molar balance approach involving vitamin D end metabolites is used to estimate fluctuating active vitamin D levels, synthesis, and demand. The ability to estimate active vitamin D levels, and synthesis may allow the establishment of actual active vitamin D levels in the body needed to suppress COVID-19 virus replication and to decrease COVID-19 virus stimulation of an exaggerated immune system inflammatory response. Determining actual active vitamin D levels and percent utilization/demand may prove vital in the treatment and monitoring of individuals with acute and sometimes life-threatening infections. This new information may allow clinicians to quickly adjust intervention with calcitriol, active vitamin D, 1,25(OH) 2 D 3 , in order to achieve rapid suppression of viruses such as the COVID-19 virus and improvement in immune system’s ability to control its inflammatory response.
Induction of artesunate resistance in Plasmodium falciparum 3D7 strain using intermittent exposure method and comparing P.fk13 sequence between susceptible and resistant strains
Authors: Barati Sahar , Haghi Afsaneh Motevalli , Nateghpour Mehdi , Zamani Zahra , Khodaveisi Sadegh
Published: May 2022

Introduction: Malaria is a major health issues in a number of countries in the world, especially tropical countries. Over the past 50 years, the resistance of Plasmodium falciparum has expanded against the antimalarial drugs that had been used to treat the disease. Recently resistance to some derivatives of artemisinin and the failure of artemisinin combination therapy (ACT) has threatened all major achievements in malaria control. Resistant strains are limited around the world, but it may spread very soon, hence the necessary to be prepared for any event regarding this matter, it is needed to organize more investigations about resistant strains and related genes. Preparation of a new resistant strain in the laboratory can provide opportunity to predict genes responsible for resistance. The aim of this study was to induce resistance to artesunate in Plasmodium falciparum 3D7 strain using intermittent exposure method and comparing P.fk13 gene sequence between susceptible and resistance strains.Materials and Methods: Plasmodium falciparum 3D7 strain was cultured according to Trager & Jensen method with some modifications. Serial concentrations between 10-2 mol/l, to 10-7mol/l were prepared, then P.falciparum 3D7 was exposed to each of the dilution to determine IC50 and lethal dose. After 24 hours exposure the rate of parasitemia and mean of growth inhibitory percent were evaluated. Sensitivity reduction process was started from the concentration of 10-7mol/l and ended at 10-2mol/l. Exposed parasites were collected after at least 27 days after cultivation in each drug concentration. DNA extraction, PCR and sequencing process were performed to investigate any possible mutations in the pfk13 gene sequence.Results: Effectiveness of 10-2mol/l concentration of artemisinin was found as a lethal dose. The resistant strain was provided in the lab, sequenced and registered in the gene bank as P.f Art -2, (accession number MH796123. 1). Alignment of this registered sample showed no mutation in P.f kelch13 gene in comparison with standard strain submitted in the Genebank. Conclusion: Results of this study showed that resistance to artesunate in malaria parasite may occur but with no mutation in the P.f kelch13 gene. Therefore, whole genome sequencing should be applied to determine mutations in resistant strains.
Study of Activation Energy and Moisture Diffusivity of Various Dipping Solutions of Ivy gourd using Solar Dryer
Authors: Elangovan Elavarasan , NATARAJAN SENDHIL KUMAR
Published: May 2022

The study is aimed to enhance the shelf life of ivy gourd through the solar drying method in open, forced and natural convection mode. Ivy gourd is treated as the primary agent to prepare medicines and the stems, leaves and flowers are used to cure diseases related to diabetics, ulcer, skin. The normal shelf life is 2–3 days and it can be increased up to 6 months with an effective drying process. The experiment is intended to find the best drying process among the open, natural and forced convection mode with an initial dipping method with ascorbic acid, lemon juice, sugar solution, honey solutions individually and a control sample (without dipping). A 3kg sample of ivy gourd is dipped in 10g/L of each of the solutions and it is used for the three drying processes individually. The obtained results are indicating that the forced convection method for ascorbic acid is best among the other drying method, with the highest moisture diffusivity is 7.88×10− 8 m2/s and the lowest activation energy of 21.12 kJ/mol. It was observed that the drying kinetics of ivy gourd should be considered an indicator of efficiency for solar drying technique from an environmental safety perspective. The influence of dipping solution and drying mechanisms on the functionalities of drying are discussed with suitable illustrations.
Impact of historical land cover changes on land surface characteristics over the Indian region using the Land Information System.
Authors: jose vibin , Chandrasekar Anantharaman , Reddy Suraj
Published: May 2022

The present study has employed a regional Land Surface Model (LSM) to investigate the impact of historical land cover changes on land surface characteristics over the Indian subcontinent for the period of 1930-2013. Four simulations that include a control run and three experiment runs are performed with the Noah 3.6 LSM within the Land Information System (LIS). The control run is performed with a MODIS-IGBP land cover map, while the three experimental runs are performed with three different potential land cover maps for the years 1930, 1975, and 2013. The potential land cover maps for the above three simulations are developed by blending the MODIS-IGBP data set with the fractional forest cover data set; the latter data is available for the years 1930, 1975, and 2013. Results indicate that the historical land cover change (1930 to 2013) has reduced the annual mean of latent heat flux and net surface radiation over the Indian domain by -24.74 W/m 2 and -14.18 W/m 2 respectively, while the sensible heat flux and the soil temperature has increased by 4.97 W/m 2 and 2.78 K. The annual mean change in latent heat flux, sensible heat flux, and soil temperature demonstrate that the largest changes occur when the land cover changes from forest to urban land as compared to forest to cropland, forest to grassland and forest to open shrubland. The annual mean change in latent heat flux is moderately large for the land cover change from forest to open shrubland when compared to forest to grassland and forest to cropland. The above is attributed to the effects of evapotranspiration, which has high values for the cropland followed by grassland and open shrubland. Furthermore, the triple collocation method is employed to assess the impact of historical land cover change on soil moisture. Results indicate that the triple collocation method effectively demonstrates the impact of land cover change on soil moisture.
Gastric cancer in patients aged younger and older than 50 years: characteristics of gastric cancer and survival analysis
Authors: Kovalenko N. V. , Zhavoronkova V. V. , Ivanov A. I. , Postolov M. P. , Tolstopyatov S. E. , Dzhafarov D. D. , Pavlovskaya P. M. , Suvorov V. A.
Published: May 2022

Objective. To study clinical and pathological characteristics of gastric cancer in patients aged younger and older than 50 years, who received anticancer treatment including surgery, as well as to identify prognostic factors for overall survival of these patients.

Material and methods. A retrospective study of surgical treatment outcomes was conducted in 350 gastric cancer patients, who were divided into 2 groups. The study group included 34 (9.71 %) patients aged 50 years and younger and the control group consisted of 316 (90.29 %) patients aged 51 years and older.

Results. The analysis of treatment outcomes and survival rates was carried out. The diffuse-type gastric cancer was more frequently diagnosed in younger than in older patients (p<0.001), and asymptomatic disease often present in younger patients (p<0.001). There were no differences in the extent of surgery between the groups (p=0.613). The overall survival rate was lower in the control group than in the study group (p=0.002). The multivariate analysis revealed that a worse prognosis was observed in patients of the control group (hr=12.71), with regional lymph node metastases (hr=2.64), distant metastases (hr=1.83), iii/iv stage of the disease (hr=2.01), lymphovascular (hr=3.15) and perineural invasion (hr=2.46), as well as with postoperative complications (hr=2.12). Adjuvant chemotherapy improved the disease prognosis (hr=0.35).

Conclusion. Specific clinical and pathological features predicted survival of gastric cancer patients aged younger and older 50 years.
Early postoperative complications after liquid nitrogen – based cryoablation therapy for localized kidney cancer
Authors: Shchekuteev N. A. , Nosov A. K.
Published: May 2022

The purpose of the study was to identify risk factors for the development of early postoperative complications after cryoablation of localized kidney cancer.

Material and methods. The study included 56 patients with kidney cancer who underwent cryoablation as a treatment option. Cryoablation for localized kidney cancer was performed using the liquid nitrogen-based cryogenic device. Early postoperative complications during the 30-day follow-up period were classified according to the clavien-dindo system.

Results. The univariate analysis included 9 predictor factors that affected the risk of developing complications after kidney cancer cryoablation. However, only 2 factors were associated with an increased risk of postoperative complications: tumor localization in the right kidney (odds ratio – 0.2619, 95 % confidence interval – 0.08553–0.8020; p=0.019) and localization in the upper kidney pole (odds ratio 0.09955, 95 % confidence interval – 0.01872–0.5292; p=0.0068).

Conclusion. Liquid nitrogen-based cryoablation therapy for localized kidney cancer was shown to be an effective and safe treatment option with a low incidence of postoperative complications.
Epidemiological assessment of the most common cancers among urban and rural male populations
Authors: Vazhenin A. V. , Novikova S. V. , Tyukov Yu. A. , Kotov A. A.
Published: May 2022

According to the who data, lung cancer (lc) is the most common cancer (nearly 13,0 %) and prostate cancer (pc) is the second most common cancer (11,0 %) in men worldwide. In the chelyabinsk region, pc has been the most common cancer since 2019, accounting for 18,3 % of all cancer cases in males, and lc has become the second most common cancer, accounting for 6,8 %.

The purpose of the study was to evaluate the epidemiological situation in terms of the most common cancers (lc and pc) in a male population of rural municipal areas in the constituent entity of the Russian Federation.

Material and methods. The incidence and mortality of lung and prostate cancers were analyzed in 1020 males from five rural municipal districts of the chelyabinsk Region, territorially included in the magnitogorsk oncological cluster. Data were obtained from the population cancer Registry of the chelyabinsk Region for 2010–2019.

Results. Over a ten-year period, the average detection rates for lc and pc were 103.59 ± 3.28 and 50.75 ± 4.86, respectively per 100,000 men in rural municipal areas. The average 1-year mortality rates from lc and pc were 59.33 ± 2.14 % and 21.11 ± 2.89 %, respectively. The average overall lc mortality was 85.44 ± 5.1 deaths per 100,000 men and the average overall pc mortality was 23.04 ± 1.26 deaths per 100,000.

Discussion. The rates of the 1-year mortality from lc and pc, as well as the rates of the overall mortality from lc in men of rural municipal areas were higher than those in urban areas, demonstrating the tendency to increase.

Conclusion. To ensure access to oncology medicine for patients in rural areas, private medical oncology clinics are involved on the basis of public-private partnership.
Issues of diagnosis and treatment of metastases in the spine and long bones
Authors: Bukharov A. V. , Erin D. A. , Derzhavin V. A. , Yadrina A. V.
Published: May 2022

Purpose: to conducted a systematic analysis of data available in the current literature, modern diagnosticalgorithms, prognostic factors, survival and options for surgical treatment of metastases in the spine andlong bones of the extremities.

Material And Methods. The review included data from randomized clinical trials evaluating various diagnostic algorithms for detecting bone metastases, the frequency of metastases to the vertebral column and long bones, their number, and options for surgical or radiation treatment published over the past 10 years. The review also evaluated various prognostic factors that can be used to determine the patient’s life expectancy.

Results. Diagnostic algorithms and scales that help choose treatment strategy, taking into account prognostic factors, were published. The treatment outcomes in patients with spine and long bone metastases were shown to be improved due to personalized surgical treatment strategies.

Conclusion. Further studies are needed to identify new prognostic factors determining the oncological outcomes in patients with bone metastases. This will lead to the optimization of surgical treatment methods and the development of new algorithms for choosing the extent of surgery in patients with bone metastases.
Effective theory for matter in non-perturbative cavity QED
Authors: Román-Roche Juan , Zueco David
Published: May 2022

Starting from a general material system of
NN
particles coupled to a cavity, we use a coherent-state path integral
formulation to produce a effective theory for the material degrees of
freedom. We tackle the effects of image charges, the
A^2A2
term and a multimode arbitrary-geometry cavity. The resulting
(non-local) action has the photonic degrees of freedom replaced by an
effective position-dependent interaction between the particles. In the
large-NN
limit, we discuss how the theory can be cast into an effective
Hamiltonian where the cavity induced interactions are made explicit.
The theory is applicable, beyond cavity QED, to any system where bulk
material is linearly coupled to a diagonalizable bosonic bath. We
highlight the differences of the theory with other well-known methods
and numerically study its finite-size scaling on the Dicke model.
Finally, we showcase its descriptive power with three examples: photon
condensation, the 2D free electron gas in a cavity and the modification
of magnetic interactions between molecular spins; recovering, condensing
and extending some recent results in the literature.
Experimental study on the treatment of acid mine drainage containing heavy metals with domestic waste pyrolysis ash
Authors: Li Xiangdong , Guo Yanwen , Cai Jieying , Bao Wei
Published: May 2022

Acid mine drainage (AMD) is a special kind of acidic wastewater produced in the process of mining and utilization. In this study, AMD was treated using the adsorption method. Domestic waste was prepared by pyrolysis, and the resulting waste pyrolysis ash adsorbent was studied experimentally by a static adsorption test to treat metal ions in AMD. The results showed that the maximum adsorption amounts of Zn2+, Cu2+, Mn2+, Fe2+, Pb2+, and Cd2+ reached 0.425, 0.593, 0.498, 18.519, 0.055, and 0.039 mg/g, respectively, when the amount of pyrolysis ash was added at 30 g/L, the initial pH of the water was 4.1 and the reaction time was 150 min. It was found that the waste pyrolysis ash could be reused at least three times by using Na2S as the regeneration agent. The SEM and BET characterization results prove that its large specific surface areas and well-developed pore structures have the potential to promote the adsorption of metal ions. The pseudo-second-order kinetic equation and Freundlich adsorption isotherms fit the adsorption process well, and the experiments reveal that the metal ions in AMD are well treated by waste pyrolysis ash through adsorption, flocculation and chemical precipitation. Waste pyrolysis ash has great potential for the treatment of acid mine drainage, providing a new approach to solid waste disposal and new ideas for water treatment as a low-cost alternative material.
Usabilidade de bombas de infusão e segurança do paciente na terapia intensiva: revisão integrativa
Authors: De Oliveira Fernanda Dos Anjos , Paes Graciele Oroski , Moreira Ana Paula Amorim , De Araújo Poliana Moreira
Published: May 2022

Trata-se de uma revisão integrativa cujo objetivo é: Identificar nas produções científicas como o manejo das Bombas de Infusão pela equipe de enfermagem impacta na segurança do paciente nas Unidades de Terapia Intensiva. O levantamento foi realizado nas bases de dados da Biblioteca Virtual de Saúde: Medline, Lilacs e Bdenf; e Web of Science Core Collection. Foram selecionados 20 artigos de 2014 a 2019, onde 76% tratavam da usabilidade de tecnologias, alguns abordando as dificuldades ou barreiras encontradas na manipulação durante a incorporação de novas bombas, e os demais, de dispositivos já incorporados. Constatou-se que a equipe de enfermagem é a profissão de destaque no que concerne à segurança do paciente nos mais variados cuidados. Foi possível observar que a usabilidade adequada das bombas durante a programação de infusões assegura uma assistência de qualidade.
Perfil clínico da gestação tardia em um município brasileiro de fronteira
Authors: Tibes-Cherman Chris Mayara , Camargo Carla Regina Moreira , Flores Lucinar Jupir Forner , Silva-Sobrinho Reinaldo Antonio , Munhak da Silva Rosane Meire , Zilly Adriana
Published: May 2022

Introdução: o adiamento da gestação ocorre por motivos diversos e possui maior risco de desenvolver complicações maternas, fetais e neonatais. O período do pré-natal se torna um momento propício para promoção da saúde dessas gestantes. Objetivo: descrever o perfil clínico da gestante com idade igual ou superior a 35 anos em um município de tríplice fronteira. Métodos: pesquisa quantitativa, do tipo retrospectiva e descritiva. Os dados são de prontuários de mulheres com idade igual ou maior que 35 anos que passaram por parto no período de 2012 a 2016. Para análise dos dados foi realizado o teste Qui-quadrado. Resultados: no período ocorreram 2.605 partos de gestações tardias, a maioria era brasileira e multípara e o parto cirúrgico o mais realizado. Quanto ao pré-natal, a maioria realizou. As intercorrências gestacionais mais encontradas foram a hipertensão arterial, diabetes mellitus e a pré-eclâmpsia. O parto cirúrgico teve maior incidência para prematuridade, baixo peso e como desfecho neonatal, a unidade de terapia neonatal. Conclusão: o perfil clínico das gestantes estudadas corrobora com outros resultados nacionais.  Diante dos resultados evidenciados, destaca-se a importância dos profissionais de saúde conheçam os fatores de risco que as gestantes tardias estão expostas, para atuarem na prevenção de tais agravos.
Experiências brasileiras no acompanhamento de crescimento e desenvolvimento infantil no contexto da Atenção Básica
Authors: Souza Laianne Santos Barbosa de , Jacob Lia Maristela da Silva , Lucena Eudes Euler de Souza , Costa Raphael Raniere de Oliveira
Published: May 2022

Objetivo: Identificar as experiências brasileiras no acompanhamento de crescimento e desenvolvimento infantil no contexto da Atenção Básica. Método: Trata-se de um estudo do tipo Revisão Integrativa de Literatura. As bases de dados utilizadas nesse estudo foram: Scientific Eletronic Library Online, Literatura Latino-Americana e do Caribe em Ciências da Saúde e SCOPUS. Resultados: Durante a busca inicial foram encontrados setenta e oito artigos, onze artigos repetiam-se dentro das bases e por esse motivo, a amostra final foi composta por oito artigos. O acompanhamento do crescimento e desenvolvimento infantil é realizado por meio de consultas na ESF e, em sua maioria, com ações de aferição de medidas antropométricas, verificação do esquema vacinal e orientação nutricional. Conclusão: Foi possível identificar experiências de consultas que ainda estão voltadas para o modelo biomédico, pautado na queixa conduta. É preciso que os profissionais atuantes na Atenção Básica recebam capacitação de qualidade, para que suas ações sejam efetivas na prevenção e promoção de saúde infantil.Descritores: Desenvolvimento infantil; Atenção Primária a Saúde; Assistência integral a saúde.
Yoga como prática integrativa e recurso terapêutico no apoio ao aleitamento materno
Authors: Aguiar Camila Clara Viana de , Alves Valdecyr Herdy , Marchiori Giovanna Rosario Soanno , Rodrigues Diego Pereira , Pereira Audrey Vidal , Vieira Bianca Dargam Gomes , Branco Maria Bertilla Lutterbach Riker , Felício Felipe De Castro
Published: May 2022

Objetivo: descrever a utilização da Yoga no apoio ao aleitamento materno, a partir do olhar das nutrizes. Método: trata-se de um estudo exploratório, descritivo com abordagem qualitativa, com dez mulheres lactantes, do município de Niterói - RJ, no período entre maio e setembro de 2018, utilizando-se como ferramenta de produção dos dados a entrevista estruturada, oficina de Yoga e diário de campo. Os dados foram submetidos à análise de discurso na modalidade temática. Resultados: Foram identificadas três categorias: A Yoga como apoio emocional e físico para as mães; A assistência da equipe de saúde, e os significados da vivência durante o processo de parturição e amamentação; e A relação mãe-bebê como base para o bem-estar e segurança materna e continuidade da amamentação. Conclusão: identifica-se a convergência entre Yoga e aleitamento materno, uma vez que os processos fisiológicos e psíquicos se manifestam na saúde do corpo físico, interligados holisticamente. Os sentidos e emoções negativos, relatados no processo de aleitamento, foram minimizados com a utilização da Yoga como recurso terapêutico.
Relação do letramento funcional em saúde com a insuficiência renal em pessoas com diabetes mellitus
Authors: Santos Júnior Jair Luiz Dos , Chaves Camilo Marta Regina , Ramos Vieira Santos Isabel Cristina , Araújo Santana Rosas Marília , Rodrigues da Silva Jullyane Rebeca , Araújo de Medeiros Lílian Katiússia , Melo Bezerra Jéssica Naylla De , Oliveira de Andrade Luz Givaneide
Published: May 2022

Objetivo: analisar a relação entre o letramento funcional em saúde e a diminuição da capacidade da função renal de pessoas com diabetes mellitus atendidas em uma unidade de referência em saúde do estado de Pernambuco. Método: estudo descritivo de corte transversal com uma abordagem quantitativa, a amostra foi de 70 participantes, que se submeteram à avaliação do nível de letramento funcional em saúde, através do questionário Brief Test of Functional Health Literacy in Adults (B-TOFHLA), e à mensuração da taxa de filtração glomerular estimada. Para a análise, foram utilizados os testes estatísticos de Qui-quadrado com correlação de Pearson, o T de Student e Mann-Whitney. Resultados: os resultados principais foram a associação estatística entre o letramento funcional em saúde inadequado, taxa de filtração glomerular estimada e a creatinina sérica reduzidas. Conclusão: este estudo mostrou associação estatística entre letramento funcional em saúde com variáveis primordiais no controle e prevenção da doença renal crônica em pessoas com diabetes mellitus, esses dados podem subsidiar o enfermeiro na busca de estratégias para promover aos pacientes a execução do autogerenciamento em saúde de modo a minimizar as complicações dessa patologia.
Práticas de enfermeiros sobre imunização: construção compartilhada de tecnologia educacional
Authors: Nascimento Camilla Cristina Lisboa do , Monteiro Diully Siqueira , Rodrigues Ivaneide Leal Ataíde , Nogueira Laura Maria Vidal , Santos Felipe Valino dos , Pereira Alexandre Aguiar
Published: May 2022

Objetivos: Conhecer a percepção de enfermeiros da Atenção Primária em Saúde a respeito dos conhecimentos dos usuários sobre imunização; Identificar as práticas desses enfermeiros sobre imunização; Construir, de forma compartilhada, uma tecnologia educacional sobre imunização. Método: Pesquisa metodológica qualitativa, realizada em 21 Unidades Municipais de Saúde em Belém-Pará, com 23 enfermeiros que atuavam em sala de imunização. A coleta de dados foi por meio de entrevistas individuais submetidas à análise de conteúdo temática. Resultados: Organizaram-se duas categorias: “Percepção dos enfermeiros sobre os conhecimentos dos usuários no contexto da imunização” e “Ações de educação em saúde na rotina das práticas relativas à imunização e elaboração da tecnologia educacional”, que possibilitaram a construção de uma cartilha com orientações baseadas no produto dessas categorias. Conclusão: Os enfermeiros têm percepção dos conhecimentos dos usuários sobre a imunização. Reconhecem a importância de práticas educativas, embora não consigam realizá-las efetivamente, devido dificuldades do cotidiano gerencial e assistencial. A participação dos enfermeiros na construção da cartilha foi fundamental para obter-se uma ferramenta adequada a intermediar suas ações educativas junto aos usuários com potencial de colaborar significativamente para a atuação da enfermagem em salas de vacina.
Síndromes hipertensivas específicas da gestação provocam desconforto respiratório agudo em recém-nascidos
Authors: Cesar Nayara Franklin , Coelho Amanda Santos Fernandes , Sousa Marília Cordeiro de , Alves Taynara Cassimiro de Moura , Silva Priscila Salomão da , Guimarães Janaina Valadares
Published: May 2022

Objetivo: Associar as síndromes hipertensivas específicas da gestação (SHEG) com desconforto respiratório agudo em recém-nascidos (RN). Metodologia: Estudo transversal, prospectivo, composto por 130 puérperas com SHEG e 142 RN. Os dados foram coletados através de questionário entre junho e setembro de 2018. Foram utilizados os testes de qui-quadrado de Yates e Exato de Fisher. Resultados: O diagnóstico de SHEG mais prevalente foi pré-eclâmpsia (48,46%). Predominou RN prematuro (62,68%), que necessitou de cuidados intensivos neonatais (61,36%). O diagnóstico de pré-eclâmpsia associou-se a prematuridade (0.01744), baixo peso (0.009306), desconforto respiratório (<0.0000001) e uso de suporte ventilatório (<0.0000001), e de pré-eclâmpsia sobreposta associou-se com desconforto respiratório (0.0006261) e uso de suporte ventilatório (0.0006261). Conclusão: É importante identificar precocemente as SHEG e oferecer uma assistência de qualidade durante o processo gravídico para reduzir os desfechos neonatais desfavoráveis e a taxa de mortalidade infantil.Descritores: complicações da gravidez, gravidez de alto risco, hipertensão, pré-eclâmpsia.
Independência no autocuidado nos doentes com acidente vascular cerebral: contribuição da enfermagem de reabilitação
Authors: Santos José Miguel , Prata Ana Paula , Cunha Isabel Cristina Kowal Olm , Reis Santos Margarida
Published: May 2022

Objetivos: Identificar o número de dias necessários à obtenção de ganhos em independência e quais estes ganhos, em indivíduos com acidente vascular cerebral internados num serviço de Medicina Física e Reabilitação, após intervenção do Enfermeiro de Reabilitação. Método: estudo quantitativo, descritivo e retrospetivo. Analisados os registros de enfermagem referentes aos doentes com acidente vascular cerebral, internados no período de janeiro de 2013 a dezembro de 2014. A colheita de dados realizou-se em instrumento construído para este estudo de análise documental. Resultados: Nos registros de 96 pacientes, constatou-se que na admissão mais de 90% apresentavam algum grau de dependência nos autocuidados de higiene, arranjo pessoal e vestir-se. Na alta mais de 50% adquiriram independência nesses autocuidados. Foram necessários 9 a 28 dias para a aquisição da independência. Conclusão: os resultados obtidos permitiram concluir que se verificou a aquisição de ganhos em independência nos três autocuidados estudados. Sugere-se outros estudos que permitam perceber qual o contributo do Enfermeiro Especialista em Enfermagem de Reabilitação para a obtenção destes ganhos.Descritores: Acidente vascular cerebral; enfermagem em reabilitação; autocuidado.
Assistência de enfermagem hemodiálise: (re)conhecendo a rotina do enfermeiro
Authors: Marinho Ingrid Veríssimo , Santos Davydson Gouveia , Bittelbrunn Caroline , De Carvalho Andrezza Lira , Vasconcelos Nídia Carolina Bandeira , Silva Milécyo De Lima
Published: May 2022

Objetivo: Conhecer a rotina do enfermeiro no setor de hemodiálise de um hospital público do Nordeste brasileiro. Metodologia: Estudo de campo de natureza exploratória e descritiva, abordagem qualitativa. Desenvolvido no setor de hemodiálise de um hospital público localizado em Campina Grande, Paraíba, com todos os enfermeiros atuantes no setor. A coleta de dados ocorreu em setembro de 2017, por meio de entrevista semiestruturada, e analisada seguindo a teoria proposta por Bardin. Resultados: Foram entrevistados enfermeiros com idade média de 41 anos, predominância do sexo feminino e com tempo médio de oito anos em atuação no setor de hemodiálise. Da análise de conteúdo emergiram as seguintes categorias: Atribuições da Enfermagem no setor de hemodiálise; Gerenciamento de enfermagem no serviço de hemodiálise; Sistematização da assistência de enfermagem no serviço de hemodiálise; Adversidades e complicações encontradas no setor de hemodiálise; e Ações da equipe de enfermagem para minimização dos riscos e possíveis intercorrências. Considerações finais: A multiplicidade de atribuições e atividades na rotina de enfermeiros do setor de hemodiálise ficou evidente em nosso estudo, que mostrou a essencial atuação e o protagonismo do enfermeiro dentro de um setor tão específico e de alta complexidade.
O lúdico como recurso terapêutico no tratamento de crianças hospitalizadas: percepção dos enfermeiros
Authors: Silva Jocelle De Araújo , De Azevedo Elisângela Braga , Barbosa Josefa Cristina Gomes , Lima Maria Karoline Santos , Cantalice Anajás Da Silva Cardoso , Ramalho Millena Cavalcanti , Barbosa Hevillyn Cecília Ventura
Published: May 2022

Objetivo: descrever a percepção dos enfermeiros quanto ao uso do lúdico como recurso terapêutico no tratamento de crianças hospitalizadas. Método: pesquisa exploratória, descritiva e qualitativa, realizada na ala pediátrica de um Hospital de Urgência e Emergência da Paraíba/Brasil. Os dados foram coletados por meio de entrevista semiestruturada e foram analisados por meio da técnica de análise de conteúdo. Resultados: participaram dez enfermeiras que atuam no referido setor. Emergiram duas categorias temáticas: “Concepção dos enfermeiros sobre o lúdico como recurso terapêutico” e “Benefícios e desafios do lúdico como recurso terapêutico”. Conclusão: confirmou-se que os enfermeiros possuem uma concepção positiva sobre a relevância e os vários benefícios da inserção do lúdico no ambiente hospitalar pediátrico.
Idosos hospitalizados com tempo de permanência prolongado: contribuições para o cuidado de enfermagem
Authors: Diniz Jamylle Lucas , Moreira Andréa Carvalho Araújo , Teixeira Iane Ximenes , Oliveira Francisco Eduardo Silva de , Sousa Vítoria Lídia Pereira , Santana Jaqueliny Mendes , Azevedo Samir Gabriel Vasconcelos
Published: May 2022

Objetivo: realizar cuidados de enfermagem em idosos hospitalizados com tempo de permanência prolongado com base na teoria de Virginia Henderson e mediado pela pesquisa-cuidado. Método: Utilizou-se abordagem quanti-qualitativa por meio da pesquisa-cuidado, embasada na Teoria das Necessidades Fundamentais de Virginia Henderson. O estudo foi realizado em um hospital do estado do Ceará entre os meses de julho de 2017 a junho de 2018. Participaram idosos com idade igual ou superior a 60 anos e que estiveram hospitalizados em quatro unidades de internação em permanência prolongada.  Para a análise dos dados utilizou-se o Software R. Resultados: Participaram 30 idosos. O sexo feminino predominou (63,33%), com distribuição etária média de 71,17 anos. A maioria eram casados (56,66%), mais da metade não possuía escolaridade (56,67%) e 93,34% eram aposentados. Predominaram-se as necessidades referentes ao domínio fisiológico. Foram identificados 16 diagnósticos de enfermagem e realizadas 42 intervenções. Conclusão: A identificação dos diagnósticos e intervenções de enfermagem fundamentados na teoria de Henderson, realizado através da pesquisa-cuidado, foram essenciais para interação entre pesquisador e pesquisados-cuidados, com foco nas necessidades de cada indivíduo.