bluuebunny/crossref_metadata_2025 huggingface dataset:
Where do we draw our last breath? A comparative analysis of factors associated with places of death in European countries
Authors: Srdelic Leonarda
Published: October 2024

This paper investigates whether a shift towards formal long-term care (LTC), typically associated with increased public spending in LTC, correlates with a lower likelihood of dying in hospitals compared to homes or care homes. Additionally, the study aims to assess how demographic, socioeconomic, and health-related variables are associated with the place of death across European countries. For this purpose, the study employs multinomial logistic regression on the data concerning 16,633 individuals aged 50 and over, who died between 2004 and 2021 in 24 European countries. The countries are grouped in two country groups to control for variations in their LTC systems. The first group consists of countries with more generous public funding for LTC, while the second group includes those where LTC is less funded and structured. Results indicate that the place of death is associated with the country’s healthcare system, demographic characteristics, socioeconomic status, and medical conditions. While hospitals remain the most common setting for death, this trend is shifting as recent years have seen a rise in deaths at home or in care homes across both country groups.
Racial and Ethnic Disparities in the Time to Ovarian Cancer Surgery in Patients at an Integrated Health Care Delivery System
Authors: Mukherjee Amrita , Tewari Devansu , Rahimian Rombod , Chen Qiaoling , Batech Michael , Wride Patricia , Sappington Sandra , Chao Chun R.
Published: October 2024

Background: Disparities in ovarian cancer survival for African American women are multifactorial. We evaluated racial and ethnic differences in time to ovarian cancer surgery in members of an integrated health care system. Patients and Methods: In this retrospective cohort study, we identified women diagnosed with invasive epithelial-type ovarian cancer between January 1, 2008, through December 31, 2014, at an integrated health care system in the United States. We extracted data on cancer-related variables and sociodemographic variables from the health care system’s cancer registry and electronic health records. We included patients who received ovarian cancer surgery without neoadjuvant chemotherapy. We defined time to surgery as the number of days between diagnostic imaging study and surgery. We used Cox proportional hazards regression to evaluate crude and adjusted association of race and ethnicity with time to surgery. Results: Of 872 patients included, 55.1% were non-Hispanic White (hereafter, White), 24.9% were Hispanic, 14.6% were Asian/Pacific Islander (PI)/Native American, and 5.5% were African American. Median age at diagnosis was 59.0 years. African American patients were diagnosed at an older age and were more likely to come from deprived neighborhoods than other racial and ethnic groups. Median time to surgery was longer for African American patients compared with White, Hispanic, and Asian/PI/Native American patients (median days: 27.5 vs 21.0, 24.5, and 26.0, respectively; P<.0001). In adjusted models, the likelihood of having received surgery at any given time post diagnostic imaging was 31% lower for African American patients compared with White patients (HR, 0.69; 95% CI, 0.51–0.93). This likelihood was also lower for Hispanic and Asian/PI/Native American patients, but not statistically significant. Conclusions: Our findings showed that patients with ovarian cancer from racial and ethnic minorities had a lower likelihood of having received surgery at any given time post diagnostic imaging compared with White patients, demonstrating that racial and ethnic differences exist in time to ovarian cancer surgery in patients with relatively equal access to care.
Cross Efficiency Evaluation In Olive Oil Sector: A Case Study Of Aydın And Balıkesir Province
Authors: Kır Alperen , Özden Altuğ
Published: October 2024

The aim of this study is to reveal whether there is a relationship between the production activities of olive oil mills in Aydın and Balıkesir provinces, where important olive oil producers of our country are located, and the province in which they are located, and what are the determining factors on their efficiency. The main material of the study consists of data obtained from face-to-face surveys covering the 2020-2021 and 2021-2022 production seasons in a total of 131 olive oil mills, 63 in Aydın province and 68 in Balıkesir province, determined by the stratified random sampling method. Data envelopment analysis was used to calculate the effectiveness scores, and a discrete and bootstrapped regression model with 1000 repetitions was used to determine the factors affecting the effectiveness. As a result of the analysis, it was found that the olive oil mills in Balıkesir province used production inputs more effectively compared to those in Aydın province, the number of fully effective mills in Balıkesir province was higher, the mills in Balıkesir province had lower ratios of improvement compared to the mills in Aydın, and the meta-technology ratios were always higher. It has been concluded that the two provinces are close to each other, 95% of the current output is met with the current technology, and there is a significant relationship between the activities of the olive oil mills in Aydın and Balıkesir provinces and the province they are located in. In addition, it is thought that newly established mills with support and incentives make existing mills ineffective and cause market contraction, and instead, it would be more appropriate to support and encourage the revision of existing mills.
El Papel de la Infraestructura en el Desarrollo Económico del Ecuador
Authors: Burgos Limones Ariel Eron , Chang Rizo Fresia Susana , Núñez Bartolomé Elizabeth Juliana , Estrada Aguilar Jaime Leonardo
Published: October 2024

La infraestructura es clave para el desarrollo económico y la calidad de vida en América Latina y el Caribe, donde se requiere una inversión anual del 3,12% del PIB, estimándose un total de 2,2 billones de dólares hasta 2030. A pesar de las inversiones en transporte y energía, Ecuador enfrenta deficiencias significativas que afectan su competitividad. Este estudio emplea un enfoque mixto con un diseño no experimental, que integra una revisión sistemática de la literatura y un análisis de series temporales, utilizando datos de Infralatam y el Banco Mundial desde 2008 hasta 2021. Para ofrecer una perspectiva integral del fenómeno, se realizó la recolección y análisis de datos cualitativos y cuantitativos, complementada por una búsqueda exhaustiva en bases de datos académicas y la evaluación de documentos de entidades gubernamentales pertinentes. Los resultados muestran una tendencia de crecimiento en la inversión hasta 2014, alcanzando más de 4,000 millones de USD, impulsada por proyectos como la modernización de la Red Vial Estatal. Sin embargo, a partir de 2015, la inversión sufrió una caída significativa debido a la crisis económica y la pandemia de COVID-19, paralizando varios proyectos. La revisión sistemática resalta que la inversión en infraestructura impulsa el crecimiento económico, con transporte y energía como sectores cruciales. Se identifican brechas infraestructurales y la falta de recursos financieros como desafíos persistentes. Para optimizar el impacto de estas inversiones, es crucial una planificación eficiente y fomentar la participación del sector privado, elementos vitales para el desarrollo sostenible del país.
Síndrome de Burnout y Recursos Laborales en Universidades de la Región Ica, 2024
Authors: Velásquez Cabrera Marco Antonio , Loayza Gutierrez Jessenia Leonor , Ramos Sayritupac Freddy Augusto , Carpio Mayorga María Ysabel , Arriaga Cancino María Cecilia
Published: October 2024

El propósito de la investigación fue demostrar la relación existente entre Síndrome de Burnout y Recursos Laborales. Desde junio hasta agosto de 2024 se inició el estudio con docentes, administrativos de una Universidad Pública, Universidades Privadas. Se constituyo una base de datos significativa relacionadas a las Variable de investigación: Síndrome de Burnout; Categoría: Recursos Laborales. Así, para la Variable, se trabajaron las Dimensiones: Agotamiento Emocional; Despersonalización; Disminución del Desempeño Personal. En lo que corresponde a la Categoría referida se tomaron en cuenta como Sub-Categorías: Apoyo Social; Autonomía; Retroalimentación sobre el Desempeño Laboral. Se emplearon la Técnica de la Encuesta; la Técnica de la Entrevista. Se implementaron los Instrumentos de recolección de datos, denominados: Cuestionario sobre Síndrome de Burnout con 15 ítems; Guía de Entrevista sobre Recursos Laborales. Se recurrió a una Muestra representativa de 50 unidades muestrales entre docentes, administrativos de una Universidad Pública, Universidades Privadas de la Región Ica para que apliquen el Cuestionario y 06 funcionarios de las entidades de educación superior universitaria para que colaboren con la Guía de Entrevista. Los colaboradores fueron seleccionados de manera intencional, tomando en cuenta criterios de inclusión: conocimiento, manejo, experiencia en lo relacionado al tema. Al procesarse los datos obtenidos se corroboro que las variables en estudio tienen una relación significativa. Se concluye que, Agotamiento Emocional; Despersonalización; Disminución del Desempeño Personal tienen una significativa relación con Apoyo Social; Autonomía; Retroalimentación sobre el Desempeño Laboral en las entidades universitarias públicas y privadas del contexto estudiado se está vivenciando en el día a día, ya que los colaboradores demuestran cada una de las dimensiones presentadas y de otro lado, las universidades de estudio no hacen nada para brindar mejores recursos laborales que ayuden a revertir la situación problemática, todo lo contrario interpretan cualquier pedido de los docentes, administrativos como actos de rebeldía y en muchas ocasiones despiden a los trabajadores.
Peran Kelompok Tani Nekafmese dalam Meningkatkan Kesejahteraan Keluarga Katolik di Lingkungan Oeolo B Paroki Santa Maria Ratu Oeolo
Authors: Sila Elviana
Published: October 2024

Tujuan penelitian ini untuk mengetahui peran Kelompok Tani Nekafmese dalam meningkatkan kesejahteraan keluarga Katolik di Lingkungan Oeolo B Paroki Santa Maria Ratu Oeolo, dan mendeskripsikan peran Kelompok Tani Nekafmese dalam meningkatkan kesejahteraan keluarga Katolik di Lingkungan Oeolo B Paroki Santa Maria Ratu Oeolo. Metode yang digunakan dalam penelitian ini adalah metode penelitian kualitatif. Teknik  pengumpulan data dilakukan dengan wawancara, observasi, dan dokumentasi. Analisis data dilakukan pada saat pengumpulan data berlangsung, dan setelah selesai pengumpulan data pada periode tertentu. Pada saat wawancara, peneliti sudah melakukan analisis terhadap jawaban informan. Sesudahnya peneliti membuat tanggapan kritis terhadap jawaban mereka. Hasil penelitian menunjukkan bahwa Kelompok Tani Nekafmese berperan dalam meningkatkan kesejahteraan keluarga Katolik di Lingkungan Oeolo B Paroki Santa Maria Ratu Oeolo dengan menjadi: Pertama, fasilitator. Kedua, motivator. Ketiga, pendamping.
Spiritualitas Katekis
Authors: Aek Klau Yohana
Published: October 2024

In the framework of the Christian vocation, being a catechist cannot be reduced into fullfiling a job to proclaim the truth of the Christian faith and to teach People of God to live according to the Christian faith. Catechist needs to form himself acording to spirituality proper to his mission. The spirituality of catechist is fundamentally formed of openness to Word of God, truthfullness to the self, and authentic living according to Christian faith and ethics. To begin with such spirituality, one has to make a habit which is relevant to that objectives, such as, constant practice of reading the Bible and spiritual exercise, personal prayer and devotion, and honest life.
Mecánica de suelos no saturados
Authors: Rojas González Eduardo , Chávez Alegría Omar , Romero Zepeda Felipe
Published: October 2024

En épocas recientes se han visto avances notables a nivel mundial en la ingeniería civil a partir de la evolución en el mejoramiento de las propiedades de los suelos, el mayor entendimiento de los materiales y la implementación de nuevas tecnologías y procesos constructivos. En este sentido, para llevar a cabo los proyectos de construcción es fundamental comprender la gama de características de los diferentes suelos sobre los cuales se edifica la infraestructura, pues ello define el mecanismo de falla del material y cuál será su comportamiento ante las cargas impuestas, así como frente a los efectos estacionales.El presente libro muestra las teorías actuales sobre el comportamiento de los suelos no saturados, proporciona al lector los principales elementos que se deben tomar en cuenta para conocerlo y permite interpretar los resultados obtenidos en pruebas de laboratorio para trazar diseños más seguros y económicos al trabajar con estos materiales. Este conocimiento es valioso en la mecánica de suelos, ya que no sólo favorece los diseños desarollados, sino que ayuda a mitigar los daños a la infraestructura y sus obras complementarias.
Molecular detection of Cryptosporidium parvum in sheep and goats in rural areas of Al-Muthanna Province, Iraq
Authors:   Department of Parasitology, College of Veterinary Medicine, Al-Qasim Green University, Babylon, Iraq, Al-Kaabi Nawras Abdul bari Madlol , Aljobory Qasim Jawad Amer ,   Department of Parasitology, College of Veterinary Medicine, Al-Qasim Green University, Babylon, Iraq, Alkaabawi Naer Abdulbari Madlool ,   Department of Microbiology, College of Veterinary Medicine, University of Al-Muthanna, Samawah, Iraq
Published: October 2024

Background: Cryptosporidium species are widespread protozoa and are considered an important cause of diarrhea in humans and animals. Aim: The aim of this study was to identify the occurrence of Cryptosporidium parvum in diarrheic sheep and goats from the rural areas of the Al-Muthanna Province, southern Iraq, based on molecular screening using PCR. The outcomes would help in determining the distribution of C. parvum in sheep and goats in the area, as well as the risk factors for the infection. Methodology: Sixty fecal samples were collected from clinically ill sheep and goats. The samples were submitted to PCR and sequencing that targeted the 18S rRNA gene in the protozoan. Results: The PCR revealed a 60% (18 samples) and 76.67% (23 samples) positive identification of C. parvum in sheep and goats, respectively. The sequencing demonstrated nucleotide similarities with isolates deriving from Iraq (MG878399.1) and India (JN836324.1) for the sheep isolates, and with isolates deriving from South Korea (DQ054819.1) and the USA (AF159112.1) for the goat isolates. Conclusion: C. parvum is the dominant species in the sheep and goats of Al-Muthanna Province, in southern Iraq. Moreover, the phylogenetic analysis demonstrates that the current study’s isolates may share the same ancestor with local and global isolates.
Blockchain Espousal in Legal Compliance with Corporate Governance
Authors: Ali Naheeda
Published: October 2024

There is much exhilaration about blockchain technology in practically every business, including financial, and significant investments are being made worldwide. In order to uncover critical criteria for blockchain espousal in corporate governance, we undertook a systematic examination of a sample of 52 articles (10 industrial and 42 academics) through a preliminary research period from 2012 to 2020. We perform textual and empirical research to build a paradigm for decentralised autonomous governance. Additionally, we relate classic corporate governance theories to blockchain espousal using this framework. Our research also focuses on how blockchain technology may be used to improve the way corporations are run, now and in the future, as well as its possible consequences. By doing a systematic study and conducting an analysis of the text, we uncovered other gaps in the earlier academic and industrial literature and common tendencies. In addition, as part of our empirical research, we are compiling a one-of-a-kind blockchain investment database to make future investment projections. In addition, in the course of and after the COVID-19 conference, we researched the many ways blockchain technology may be used to improve corporate governance. According to our findings, previous academic publications prefer to concentrate on regulation and Initial Coin Offerings (ICOs). In contrast, previous publications in the sector have focused on exchanges and cryptocurrencies. Final thoughts on the impact of blockchain technology on corporate governance from the perspectives of behaviour, law & regulatory requirements, ethical considerations and managerial practices.
Stock Markets during Different Waves of COVID-19 Pandemic: An Empirical Study on the Comparative Significance of Information and Sentiment
Authors: Irrum Lubna , Farooq Sadia
Published: October 2024

This study has investigated the impact of Covid-19 on stock markets in perspective of cases, deaths, and sentiments during different waves of pandemic in emerging countries. In order to run analysis OLS technique have been applied. The study found that information and sentiment might have different implications for different markets, where information seemed to be. Sentiment was deemed important for USA and India, whereas information aspect was deemed important for India and Pakistan, while both sentiment and information failed to explain stock returns in China. This implied that sentiment was important for countries where pandemic was not managed or controlled, whereas information was important for countries with some control on the pandemic, and both information and sentiment were not important for the country with stringent control on the pandemic and also on media. It is recommended on findings of the study that both information and sentiment could be important in different markets, during different situations and investors should consider dynamics of individual markets for their investment decisions
Coinfección y sobreinfección bacteriana en pacientes con neumonía por COVID-19 en el Nuevo Hospital San Roque de Córdoba (2020
Authors: Molina Ana Paula , Muñoz Verónica , Olocco Cecilia , Vacaflor Liliana , Peralta Nora , Gerván Natalia
Published: October 2024

Introducción: La enfermedad por COVID-19 ha provocado que un gran número de pacientes ingresados en unidades de cuidados intensivos presenten riesgo de adquirir infecciones bacterianas secundarias. Objetivo: Describir la coinfección/sobreinfección bacteriana y el patrón de sensibilidad antimicrobiana en pacientes con COVID-19 en la Unidad de Terapia Intensiva del Nuevo Hospital San Roque de Córdoba, Argentina. Materiales y métodos: Se hizo un estudio retrospectivo, descriptivo y observacional de pacientes mayores de 18 años de edad, ingresados en la Unidad de Terapia Intensiva con COVID-19 desde marzo a diciembre de 2020. Resultados: Se incluyeron 44 pacientes; el 5% (n=2) y el 73% (n=32) presentaron coinfección y sobreinfección bacteriana, respectivamente. El 89% (n=39) se encontraba ventilado mecánicamente, con un promedio de duración de la internación de 32,2 días. El 50% de los pacientes falleció. El 61% (n=27) fueron hombres. La mediana de edad global fue de 56 años y las comorbilidades más frecuentes fueron hipertensión arterial (n=17, 39%),  diabetes mellitus (n=10, 23%), inmunosupresión (n=7, 16%), obesidad (n=5, 11%) y enfermedad pulmonar obstructiva crónica (n=5, 11%). De los cultivos microbiológicos de muestras respiratorias, se aislaron principalmente Klebsiella pneumoniae, Acinetobacter baumannii y Pseudomonas aeruginosa. Klebsiella pneumoniae presentó una sensibilidad elevada para colistín, fosfomicina, ceftazidima/avibactam y amicacina. Se observó un 61% (n=14) de Klebsiella pneumoniae productora de carbapenemasas KPC. Acinetobacter baumannii mostró mayor sensibilidad para colistín, tobramicina y amicacina, mientras que Pseudomonas aeruginosa, a amicacina, gentamicina, ciprofloxacina y colistín. Conclusión: Existe una alta prevalencia de sobreinfecciones bacterianas en pacientes con COVID-19 que requieren hospitalización, principalmente, en aquellos con comorbilidades específicas, complicaciones, estancia prolongada y ventilación mecánica.
Biotecnología aplicada al diagnóstico y tratamiento de la osteoporosis. Avances en biofármacos, bioterapias y biomarcadores. Parte 1
Authors: Sterin Prync Aida , Bagnato Julieta , Olano Lucía , Ronchi Rivara Juan Pablo , Solari Ligo María Florencia , Torrens Pierina , Carlucci Adriana Mónica
Published: October 2024

Introducción: La osteoporosis es un desorden óseo que incrementa el riesgo a padecer fracturas que constituye un problema de salud pública. Objetivos: Estudiar los avances biotecnológicos en relación con biofármacos, bioterapias y biomarcadores aplicados a la osteporosis. Materiales y Métodos: Se realizó una búsqueda bibliográfica con las palabras clave osteoporosis, biopharmaceuticals, biotherapies, microbiota, y biomarkers en MEDLINE/Pubmed, Scielo, Lilacs - BVS y Google Scholar. Se analizaron 53 trabajos científicos en inglés o español, publicados entre 2005 y 2019. Resultados: Los péptidos recombinantes análogos de la hormona paratiroidea son biofármacos aprobados como alternativas a los fármacos tradicionales en la osteoporosis. La microbiota intestinal aparece como una bioterapia en estudio. Se describen distintos tipos de marcadores y biomarcadores y el desarrollo de herramientas como el algoritmo Fracture Risk Assessment Tool (FRAX). Conclusiones: La biotecnología bioquímica y farmacéutica tiene una activa e importante participación en alternativas que pueden beneficiar la calidad de vida del paciente y disminuir el problema sanitario de esta compleja patología.
Recuento plaquetario y volumen plaquetario medio en pacientes sépticos: variación y asociación con mortalidad
Authors: Acosta Liotard Florencia Belén
Published: October 2024

Introducción: Sepsis es uno de los principales diagnósticos de ingreso a terapia intensiva. En el paciente crítico, la trombocitopenia es el desorden hematológico más común y un potente indicador que expresa un desacople fisiológico global. En estas condiciones, se puede alterar el tamaño de las plaquetas, que se detecta mediante el volumen plaquetario medio (VPM). Objetivos: Evaluar la variación del recuento plaquetario y VPM a lo largo de las primeras 72 horas de internación y su asociación con mortalidad en pacientes que permanecieron en la UTI del Hospital Italiano de Córdoba con diagnóstico de sepsis o shock séptico de cualquier etiología. Materiales y métodos: Se analizan mediciones de VPM y recuento total de plaquetas de pacientes internados en terapia intensiva, divididos en dos grupos: sépticos y controles no sépticos, al inicio, a las 24, 48 y 72 horas de internación. Resultados: El recuento plaquetario en pacientes sépticos fue menor que el de pacientes con diagnóstico no relacionado; el VPM fue significativamente mayor a partir de las 24 horas y este hecho resultó más evidente según aumentaban los días de internación. Los pacientes sépticos que mueren tienen un VPM mayor que aquellos que obtienen el alta a partir de las 24 horas y recuentos plaquetarios menores que los que obtienen el alta a partir de las 72 horas. Además, poseen un VPM superior a 10,0 fL a partir de las 24 horas de internación. Discusión: Validar este parámetro como biomarcador pronóstico en sepsis significaría tener una herramienta práctica y rápidamente disponible.
Evaluación del desempeño diagnóstico de tres ensayos serológicos para la detección de anticuerpos IgG contra SARS-CoV-2
Authors: Alcalde María Belén , Chiodini Julieta , Shepherd Safar Melanie , Accorinti Ailin , Alegre María , González María Sandra
Published: October 2024

Introducción: En respuesta a la pandemia de COVID-19 se han desarrollado y aprobado con celeridad un gran número de pruebas serológicas, en diferentes formatos, para la detección de anticuerpos contra SARS-CoV-2. Dada la gran oferta y variabilidad entre ensayos, la evaluación independiente de su rendimiento resulta fundamental. Objetivos: El objetivo de este trabajo fue analizar y comparar el desempeño diagnóstico de tres métodos de detección de anticuerpos IgG anti-SARS-CoV-2 disponibles en nuestro medio. Materiales y métodos: Se evaluaron tres tipos de ensayos serológicos, un inmunoensayo quimioluminiscente (Access® SARS-CoV-2 IgG), un enzimoinmunoensayo (COVIDAR IgG) y un inmunoensayo de flujo lateral (SARS-CoV-2 Antibody Test), utilizando muestras de suero de individuos con infección por SARS-CoV-2 superada, y sueros recolectados antes del inicio de la pandemia. Resultados: Se procesaron un total de 168 muestras, 94 sueros de individuos con infección por SARS-CoV-2 superada y 74 sueros prepandemia. Las sensibilidades de los métodos evaluados variaron entre 71,3 % y 89,4 %. La sensibilidad del ensayo COVIDAR IgG resultó ser significativamente mayor que la de los otros dos métodos (p < 0,05). Las especificidades variaron entre 95,9 % y 100 %, sin diferencias significativas entre los tres métodos. Se encontró una concordancia sustancial entre el ensayo COVIDAR IgG y el Access® SARS-CoV-2 IgG (índice kappa: 0,74), y casi perfecta entre el SARS-CoV-2 Antibody Test y los otros dos ensayos (índices kappa: 0,80 y 0,89). Conclusiones: Este estudio demuestra un adecuado desempeño de los tres ensayos en nuestra población y la existencia de concordancia entre los mismos.
Valor predictivo del sodio plasmático en pacientes internados con COVID-19
Authors: Towstyka Nadia Yasmín , Palanek María Laura , Brethauer Alejandra , Morvillo Natalia , Tarditti Adrián , Duarte Ender
Published: October 2024

Introducción: La enzima convertidora de angiotensina II es el receptor que utiliza el virus SARS-CoV2 para ingresar a las células y su bloqueo puede afectar la regulación del balance hidroelectrolítico generando, entre otras alteraciones, hipernatremia. Objetivo: Puesto que el aumento de sodio fue reportado como un factor de mal pronóstico en internados con COVID-19, nos propusimos evaluar su valor predictivo en la evolución de pacientes internados en el Hospital de Alta Complejidad del Bicentenario Esteban Echeverría. Materiales y métodos: Utilizando la base de datos del laboratorio, se analizaron los niveles plasmáticos de sodio, de forma retrospectiva, en una cohorte de 160 pacientes durante el primer semestre del año 2021. Resultados: En pacientes fallecidos (N=98), se observa un aumento significativo del sodio plasmático medido a partir de las 48 h de internación (p<0,01), que no se observa en pacientes no fallecidos (N=62). Si se comparan los resultados de sodio plasmático al quinto día de internación, se observan diferencias significativas (p<0,0001) entre ambos grupos. Para cada rango etario, es mayor el porcentaje de óbitos, si se consideran los pacientes con hipernatremia respecto de los pacientes internados en general. El porcentaje de fallecidos se incrementa en función de la edad y el grado de hipernatremia. Conclusión: Considerando los elevados valores de sodio que se observaron durante los primeros días de internación en los pacientes fallecidos y el aumento de la mortalidad en función de la mayor edad del paciente y de valores más elevados de sodio plasmático, podemos concluir que la hipernatremia tiene un valor predictivo de mortalidad significativo en los pacientes internados por COVID-19.
Método rápido y directo para detección de variantes delta y ómicron BA.1 por RT-PCR en tiempo real
Authors: Chialva Constanza Soledad , Galdi Mónica Ana María , Buscalia María Laura , Quiroz Héctor Magno
Published: October 2024

Introducción: La mayoría de las pruebas de RT-PCR utilizadas por los laboratorios comerciales y de salud pública detectan si una persona porta el virus SARS-CoV-2, pero no pueden determinar de qué variante se trata. Debido a esto, puede resultar de interés contar con pruebas que faciliten la identificación de una de las dos variantes de preocupación, con mayor circulación en la actualidad: delta y ómicron. Objetivos: Desarrollar una prueba comercial, de uso exclusivo en investigación, para la detección de las variantes delta y ómicron BA.1. Materiales y métodos: Se seleccionaron cebadores y sondas para detectar una región única y específica, con mutaciones del gen que codifica para la proteína Spike en las variantes delta y ómicron BA.1, y su versión sin mutación. Se diseñó un producto que contiene todos los componentes necesarios para detectar y amplificar ARN viral mediante la técnica de RT-PCR en tiempo real. Se llevaron a cabo las validaciones analíticas, empleando material sintético de cada variante, y las validaciones clínicas, usando un panel de 110 muestras positivas para SARS-CoV-2, previamente secuenciadas para clasificación de sus variantes. Resultados: Se desarrolló y validó un método rápido, directo y accesible para la detección de las variantes delta y ómicron BA.1 mediante RT-PCR en tiempo real, con un límite de detección menor que 10 cp/μL y una alta sensibilidad y especificidad (100%). Conclusiones: Las pruebas basadas en RT-PCR en tiempo real se pueden usar para monitorear rápidamente las variantes de preocupación de SARS-CoV-2 en países de recursos limitados, pero requieren actualizaciones a medida que surgen nuevas variantes.
Pembuatan Peta Lokasi Alternatif Peternakan Ayam Broiler Kabupaten Muara Enim Dengan Menggunakan Logika Fuzzy
Authors: Putra Putra  , Freddy Sapta Wirandha
Published: October 2024

Pemilihan lokasi peternakan ayam broiler yang optimal merupakan faktor kunci dalam menentukan keberhasilan usaha peternakan, terutama di Kabupaten Muara Enim yang memiliki potensi besar di sektor ini. Penelitian ini bertujuan untuk mengembangkan peta lokasi alternatif untuk peternakan ayam broiler di Kabupaten Muara Enim dengan menggunakan metode logika fuzzy. Pendekatan logika fuzzy dipilih karena kemampuannya dalam mengolah data yang bersifat tidak pasti dan mempertimbangkan berbagai variable yang saling berkaitan, seperti ketersediaan lahan, aksesibilitas, serta kondisi lingkungan. Hasil penelitian menunjukkan bahwa metode logika fuzzy dapat memberikan rekomendasi lokasi yang lebih adaptif dan realistis dibandingkan dengan pendekatan konvensional. Hasil akhirnya dari penilaian diperoleh 6 lokasi dengan tingkat kesesuaian “Sangat Sesuai” dengan luas total 165.631 ha yang berada di Kecamatan Tanjung Agung. Lokasi yang direkomendasikan untuk peternakan ayam broiler berada di Kecamatan Tanjung Agung Kabupaten Muara Enim dengan luas ± 72,07 ha. Peta lokasi yang dihasilkan diharapkan dapat menjadi panduan bagi para pemangku kepentingan dalam perencanaan dan pengembangan usaha peternakan ayam broiler yang berkelanjutan di Kabupaten Muara Enim.
Pengaruh Intensitas Curah Hujan Terhadap Kualitas Batubara MT-47 di Gerbong TLS II PT. Bukit Asam, Tbk.
Authors: Astrid Fadhilah  , Selfi Murnia Devi  , Putra Putra  , Muhammad Abdul Ghony
Published: October 2024

PT. Bukit Asam, Tbk. merupakan salah satu pertambangan batubara terbesar di Indonesia yang selalu memprioritaskan kualitas batubara agar sesuai dengan permintaan konsumen. Agar kesesuaian kualitas dapat terpenuhi, pengendalian mutu batubara menjadi kegiatan penting untuk penjagaan dan pemastian kualitas batubara yang dikirim ke konsumen sesuai yang tercatat dengan kontrak jual beli. Pelaksanaan penambangan dan penumpukan batubara di stockpile terdapat permasalahan yaitu berkurangnya kualitas batubara, permasalahan tersebut beberapa diantaranya adalah kurang terjaganya kebersihan jalur area gerbong dan stockpile yang kurang baik serta cuaca alam yang tidak bisa diperkirakan, salah satunya curah hujan. Kandungan air (moisture) adalah salah satu indeks yang paling penting di mana produk batubara dinilai. Penghilangan kadar air dari batubara sangat penting untuk meminimalkan kerugian ekonomi, penanganan dan masalah transportasi, dan untuk memaksimalkan nilai kalori batubara. Air yang terinfiltrasi dapat menguap, mengalir atau tetap berada di dalam timbunan. Berdasarkan analisis pengaruh curah hujan terhadap parameter Total Moisture (TM), Volatile Matter, Total Sulfur, Ash Content, Fixed Carbon, dan Gross Calorific Value terjadi kenaikan kadar tertinggi dan penurunan kadar terendah. Parameter TM kenaikan tertinggi terjadi sebesar 32,27 dan penurunan terendah yaitu 21,40. Parameter VM terjadi kenaikan kadar yaitu 36,18 dan penurunan terendah yaitu 30,95. Parameter FC terjadi kenaikan yaitu 38.09 dan penurunan terendah yaitu 32,47. Parameter ASH terjadi kenaikan kadar tertinggi yaitu 7,48 dan penurunan terendah yaitu 1,52. Parameter TS terjadi kenaikan kadar tertinggi yaitu 0,22 dan penurunan terendah yaitu 0,67. Parameter GCV terjadi kenaikan yaitu 5,517 dan penurunan terendah yaitu 4,594.
লোকসঙ্গীতের সুরে রবীন্দ্রসঙ্গীত
Authors: মৃদুলকান্তি চক্রবর্তী
Published: October 2024

রবীন্দ্রসঙ্গীতের বিপুল সম্ভার বাঙালির অন্যতম মহৎ উত্তরাধিকার। গানের বাণীর পাশাপাশি বিচিত্র সুরের সমাহারে পূর্ণ রবীন্দ্রসঙ্গীতের এই ভূবন। নব নব আঙ্গিকের পরীক্ষা-নিরীক্ষায় নিত্যনতুন সুরবিহারের প্রবণতা দেখা যায় রবীন্দ্রনাথের সমগ্র জীবন জুড়ে। শৈশবকাল থেকেই রবীন্দ্রনাথ ঠাকুরের উপর লোকসাহিত্য ও লোকসঙ্গীতের প্রভাব সর্বজনস্বীকৃত। পরে জমিদারীর কাজে দীর্ঘসময় পূর্ব বঙ্গে বসবাস এবং আরও পরে শান্তিনিকেতন প্রতিষ্ঠার সূত্রে বীরভূমে বাসকালে গ্রামীণ সুরের সঙ্গে রবীন্দ্রনাথের ঘনিষ্ঠ পরিচয় ঘটে। রবীন্দ্রনাথ নিজেও তাঁর অনেক গানকে 'রবীন্দ্র-বাউলের গান' বলে আখ্যায়িত করেছেন। রবীন্দ্রনাথের গানে সুরারোপে বাউল, সারি, ভাটিয়ালী, কর্মসঙ্গীত প্রভৃতির সুর কি মাত্রায় ও রূপে বিচিত্র বৈশিষ্ট্য নিয়ে ব্যবহৃত হয়েছে— তার উদ্‌ঘাটন-প্রয়াস বর্তমান নিবন্ধের মূল অন্বিষ্ট।
PENCEGAHAN BLACK CAMPAIGN DALAM PEMILIHAN PRESIDEN 2019 MENURUT PERSPEKTIF HUKUM POSITIF (Studi Kasus Pemilu Presiden di Kabupaten Serang)
Authors: Rizki Rahmat Alfan , Martinesya Sefa , Widad Sofyatul
Published: October 2024

Penelitian ini dilatarbelakangi dengan adanya banyak temuan Black Campaign yang peneliti temukan menjelang pemilu 2019 baik secara langsung dalam kegiatan bermasyarakat maupun secara tidak langsung yaitu melalui media massa dan media elektronik yang menurut peneliti memiliki intensitas yang cukup tinggi sebagai sarana penyebaran Black Campaign. Sehingga, peneliti merasa tertantang untuk meneliti Pencegahan Black Campaign yang berfokus di Kabupaten Serang. Tujuan penelitian ini adalah mengetahui secara yuridis tentang pencegahan Black Campaign dalam pemilihan presiden tahun 2019 di kabupaten Serang berdasarkan hukum positif. Penelitian ini menggunakan metode penelitian yuridis normatif dengan sifat penelitian deskriptif analitis, kemudian sumber data diambil dari data sekunder, dengan bahan hukum primer, sekunder dan tersier, untuk selanjutnya data-data yang diperoleh akan diolah dan dianalisis secara kualitatif. Hasil penelitian ini menunjukkan bahwa Pencegahan Black Campaign dimotori oleh Bawaslu Kabupaten Serang melalui beberapa cara, yaitu dengan membentuk kebijakan, mengadakan sosialisasi dan membangun kerjasama dengan lembaga lain. Larangan Black Campaign berdasarkan hukum positif diatur dalam KUHP dan Undang-Undang yang berkaitan dengan pemilihan umum.
Hipertansiyon Hastalarının Akılcı İlaç Kullanımı Düzeyleri ve Etkileyen Faktörler: Kesitsel Çalışma
Authors: Semerci Çakmak Vahide
Published: October 2024

Amaç: Çalışma hipertansiyon hastalarının akılcı ilaç kullanımı düzeylerinin ve etkileyen faktörlerin belirlenmesi amacıyla yapıldı.
Yöntemler: Kesitsel tipte olan bu çalışma 10 Kasım ve 30 Aralık 2023 tarihleri arasında Türkiye’nin Doğu Karadeniz Bölgesinde Bayburt şehrinde yapıldı. Çalışmaya 18 yaş ve üzeri hipertansiyon hastalığı olan 237 kişi dahil edildi. Veriler Hasta Tanıtım Formu ve Akılcı İlaç Kullanımı Ölçeği ile toplandı. Verilerin analizinde tanımlayıcı istatistikler ve çoklu doğrusal regresyon analizi kullanıldı.
Bulgular: Hipertansiyon hastalarının yaş ortalaması 57,18±6,94 (min=33, max=65) idi. Katılımcıların Akılcı İlaç Kullanımı Ölçeği puan ortalaması 58,00±3,32 (min=38 ve max=64) olduğu belirlendi. Yapılan çoklu regresyon analizinde oluşturulan modelin istatistiksel olarak anlamlı olduğu ve modele dahil edilen değişkenlerin varyansın %25’ini açıkladığı belirlendi (R2=0,255, F=2,805, p
An Evaluation Postgraduate Midwives’ Attitudes Towards Postgraduate Education: Türkiye Example
Authors: Ocak Aktürk Sibel , Kızılkaya Tuba , Güdücü Neriman , Dolgun Gülümser
Published: October 2024

Objective: To determine the academic and professional profiles of midwives studying at the Department of Midwifery in Türkiye, to examine their attitudes towards graduate education and related factors.
Methods: This study was carried out descriptive and cross-sectional study with 190 midwives actively continuing their postgraduate education and who met the inclusion criteria. The study was conducted between April 2021 and July 2021. Descriptive Information Form and Attitude Scale Towards Postgraduate Education were used to collect data.
Results: Thinking about becoming an academician in the future, being satisfied with the performance of the academicians in postgraduate education, thinking that clinical experience is necessary before postgraduate education were determined as the factors affecting the attitudes of midwives towards postgraduate education.
Conclusion: It is thought that determining the attitudes, expectations and problems of midwives towards graduate education and developing solutions for problems will increase positive attitudes towards graduate education.
Effectiveness of diet therapy compared to medical pharmacological treatment for iron deficiency anemia in residents of the temporary shelter in the Jesús del Gran Poder neighborhood, aged 18 to 75 years, Santo Domingo
Authors: Lizcano Ramírez Jennifer , Salabarria Rosero Brittany María , Mera Santos Vicky Gabriela , Chávez-Arizala Jenrry Fredy
Published: October 2024

Introduction: food plays an essential role in the incorporation of iron, a mineral necessary for the growth and development of the body. Diet therapy is applied to people who suffer from a disease; in this case, iron deficiency anemia, consisting of a decrease in hemoglobin levels in the blood due to iron deprivation.Objective: to determine the effectiveness of diet therapy compared to pharmacological treatment to treat iron deficiency anemia in people from the Jesús del Gran Poder neighborhood, in the period February-May, Santo Domingo 2021Methods: quasi-experimental longitudinal study, for data collection a sociodemographic data sheet was used and a blood count was performed to corroborate the diagnosis. The sample was divided into a control and experimental group, each group of 15 participants. The control group was given 50 g of oral iron, once a day, and the experimental group received diet therapy workshops for three months.Results: at the end of the treatment, the results of the intervention showed that 53% of the experimental group had moderate anemia and 47% had mild anemia, while 80% of the control group had anemia and 20% had mild anemia. After the intervention, 100% of both groups significantly overcame anemia, demonstrating the effectiveness of the experimental treatment.Conclusions: a decrease in iron deficiency anemia was obtained compared to the control sample; although the difference between the levels was not significant, there was an efficacy in the application of the natural treatment
Application of a Modified SegFormer Architecture for Gleason Pattern Segmentation
Authors: Ermakou Vadzim , Kosik Ivan , Nedzvedz Artsiom , Karapetsian Ryhor , Liatkouskaya Tatsiana
Published: October 2024

A key element of morphological assessment in prostate cancer (PCa) diagnostics is the Gleason score, which is based on the architecture of tumor growth in biopsy or prostatectomy samples. During this process, biopsies from the prostate's pathological areas are evaluated to identify the most common and severe architectural patterns (referred to as Gleason patterns), each of which is assigned a score in the Gleason grading system. The resulting total score serves as a critical predictor for disease progression and metastasis.
This research focuses on enhancing the efficiency of morphological examination in PCa by utilizing automatic segmentation of Gleason patterns in whole slide images (WSI) in *.svs format, with 40x magnification and an average spatial resolution of 0.258 microns per pixel. Segmentation was performed using a neural network with a SegFormer architecture, supplemented by an EdgeNeXt (small variant) subnet. The proposed solution successfully identified Gleason patterns of grades 3, 4, and 5. The best model performance for detecting combined Gleason patterns 3, 4, 5, and 4, 5 was achieved with input images sized 512x512 (tile size) and a batch size of 8, resulting in an F-score of 0.835 and 0.769, respectively.
Empowering college physical education: AI-driven training, teaching, and intelligent information processing
Authors: Tian Yu
Published: October 2024

The current status, methods utilized for Physical Education Training and Teaching System for College Students, and difficulties during information processing are all investigated in this comprehensive study. We compiled 130 empirical research on Artificial Intelligence-based Physical Education (AIPE) using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses are analysed. Research shows that AI may improve health tracking, individualized training, and analysis of sporting performance. There is a lot of promise in AIPE for individualized lessons, immediate feedback, varied classroom settings, and evaluation. The problems arise when dealing with technological dependability, privacy concerns, and the need for instructor assistance. These results give light on important questions for future AIPE. This research delves into the process of creating and launching an all-encompassing educational platform that makes use of AI and data processing methods. Our system’s goals include improving the quality of instruction, tailoring feedback to each student, and enhancing the overall learning experience. AI Algorithms powered by artificial intelligence help us shift through student test scores, identify knowledge gaps, and modify lessons appropriately. This makes sure that the curriculum meets each student’s needs. Practical exercises, quizzes, and assignments get immediate feedback through the system. It uses natural language processing (NLP) to analyse student answers, find misunderstandings, and provide help for fixing them. The system personalizes learning routes according to students’ choices, learning styles, and progress. It suggests further reading, interactive games, and group assignments. Through the automation of administrative activities, generation of analytics reports, and suggestion of pedagogical changes, the system aids instructors. It makes it easier for students and instructors to talk to one another. Data protection, overcoming AI biases, and getting teachers on board with tech-enhanced lessons are all obstacles. Future studies should aim to improve the system, confirm its efficacy, and encourage its implementation across educational institutions. Finally, there is great potential for improving higher education with an AI-based training and teaching system with strong data processing skills. Students and teachers may reap the advantages of a technologically enhanced, ever-changing learning environment.
Exploring the Relationship between Hygiene Factors and Job Satisfaction in Workplace
Authors: Mahmood Nor Asiah , Tajuddin Nur Ilyana Ismarau
Published: October 2024

The purpose of this research is to investigate the relationship that exists between hygiene factors and job satisfaction (JS) among the Royal Malaysian Navy (RMN) personnel in the workplace. The focus shall be directed toward the diligent personnel on board at Lumut Naval Base. The present study adopts a quantitative analysis methodology, employing a straightforward descriptive approach and correlation analysis through SPSS 23, wherein a sample of 220 employees was randomly selected for analysis. The empirical evidence suggests that there exist notable associations between job satisfaction (JS) and various factors, namely company policy, salary and benefits, and interpersonal relationships. The variables of job security and working conditions do not exhibit a statistically significant correlation with job satisfaction. The findings of this study suggest that there exists a noteworthy correlation between variables towards Job Satisfaction (JS). Therefore, there is no significant correlation between Job Security and Working Conditions in JS. The study's impact extends beyond the organization, encompassing the broader field, as it adds to the body of literature about the research elements. The utilization of models and theoretical frameworks in prospective investigations presents a distinct point for comprehending and interpreting phenomena that represents a noteworthy innovation within the context study.
The Impact of Foreign Direct Investment, Trade Value on the Economic Growth of Greater Mekong Subregion (GMS)
Authors:   Department of Technology and communication Luang Phabang Province, PHALAMMIXAY Anousone
Published: October 2024

In the study entitled “The impact of foreign direct investment, trade value on the economic growth of the Greater Mekong Subregion countries” which aims to study the changes of foreign direct investment, trade value on the economic growth of the Greater Mekong Subregion countries (GMS) from 2005–2022, and analyze the impact of foreign direct investment, trade value on the economic growth of the Greater Mekong Subregion countries (GMS), The data used in the study is geographical data. This study uses descriptive statistics to analyze changes and uses the estimation method of ordinary least squares (OLS) through a statistical program. Through the analysis of changes in foreign direct investment, trade value, and gross domestic product of GMS, it was found that, since GMS was established in 1992, the condition of foreign direct investment, trade value, and gross domestic product of GMS has been changing continuously due to the influence of Chinese investment that has come to invest in the region in terms of transportation infrastructure and electricity. In terms of trade, there are trade relations among the group of GMS countries, focusing on facilities for transportation and trade in the region. Cooperation in the region, contributing to economic growth and reducing poverty, as well as responding to the demand for products in the region, developing agriculture in urban areas, promoting GMS as a tourist source, and making the total domestic product of the countries in the region grow. A temporary drop in foreign direct investment, trade value, and gross domestic product of the GMS is due to the Mekong Delta member countries being affected by the financial crisis in Asia, political unrest, the financial crisis in China, and the spread of the COVID-19 disease. Analysis of the effect of foreign direct investment and trade value on the economic growth of the GMS countries by testing the relationship found that both the value of foreign direct investment and the value of international trade are related in the same direction to economic growth: if the value of foreign direct investment in the GMS countries increases by 1%, it will result in an increase in the total domestic product by 0.1225%, and if the value of trade in the GMS countries increases by 1%, it will result in an increase in the total domestic product by 0.7566% through statistical significance of 0.01.