bluuebunny/crossref_metadata_2025 huggingface dataset:
Veneno de avispas de los géneros Parachartergus sp. y Polybia sp (Vespidae: Polistinae) en Costa Rica: un potencial biológico por explorar
Authors: Rodríguez-Picado Ivonne , Chavarría-Pizarro Laura , Centeno-Cerdas Carolina
Published: September 2022

América Latina alberga gran diversidad de especies del orden Hymenoptera, dentro de las cuales se encuentran las avispas de los géneros Polybia y Parachartergus. Se ha caracterizado que las picaduras de avispas causan reacciones como permeabilidad vascular, activación y movilización de células inflamatorias y moléculas mediadoras de inflamación. Esto ha incrementado el interés biotecnológico en el veneno de avispas, con el fin de identificar componentes bioactivos involucrados en las respuestas biológicas, en busca de moléculas con actividades específicas. En las últimas décadas, se ha encontrado que las más prometedoras son los péptidos mastoparán y otros péptidos anticancerígenos (ACPs). El potencial de estos péptidos se atribuye principalmente a su tamaño y estructura anfipática, que les permite interactuar diferencialmente con las membranas celulares.
El perfil proteómico reportado para el veneno de Polybia paulista, en Brasil, motiva a estudiar también el de diferentes insectos en Costa Rica, considerando que los componentes del veneno pueden variar entre diferentes zonas geográficas, así como en función de sus depredadores y presas. El presente documento pretende resaltar el potencial farmacológico que encierra el veneno de avispas de los géneros Parachartergus sp. y Polybia sp., principalmente para tratar el cáncer, aprovechando la biodiversidad y capacidades tecnológicas de Costa Rica, aportando con esto a la lucha contra una de las mayores causas de morbilidad y mortalidad a nivel mundial.
El perfil proteómico reportado para el veneno de Polybia paulista, motiva a estudiar también el de diferentes insectos en Costa Rica, considerando que los componentes del veneno pueden diferir entre diferentes zonas geográficas, así como entre especies y géneros en función, por ejemplo, de sus depredadores y presas. El presente documento pretende resaltar el potencial farmacológico que encierra el veneno de avispas de los géneros Parachartergus sp. y Polybia sp., principalmente para tratar el cáncer, aprovechando la biodiversidad y capacidades tecnológicas de Costa Rica, aportando con esto a la lucha contra una de las mayores causas de morbilidad y mortalidad a nivel mundial.
Amenazas tecnológicas en el cantón La Unión, Cartago, Costa Rica
Authors: Rodríguez-Campos Jorge Eduardo , Fernández-Arce Mario
Published: September 2022

Este artículo describe la distribución de las amenazas tecnológicas en el cantón La Unión de Cartago y muestra los radios de máximo alcance por eventuales explosiones en gasolineras. En las industrias, gasolineras y el poliducto de la Refinadora Costarricense de Petróleo (RECOPE) podrían suscitarse incidentes tecnológicos lo que demanda estudios para conocer su capacidad destructiva. El trabajo da a conocer el potencial de los incidentes tecnológicos en el cantón La Unión y servirá para manejar más eficientemente estos peligros tecnológicos. Se utilizó una relación de linealidad y proporcionalidad con datos del Servicio Geológico Mexicano para estimar el alcance de explosiones en gasolineras. Con el fin de conocer la extensión de las fugas de gases industriales se utilizó como guía un estudio sobre amenazas químico-tecnológicas de la Gran Área Metropolitana (GAM) y se revisó referencias sobre incidentes ocurridos previamente. Un estudio de campo, para verificar la presencia de asentamientos humanos cerca del poliducto, y revisión bibliográfica permitieron tener una idea del potencial de amenaza del poliducto. Los resultados indican que los radios de máximo peligro asociados a explosiones de gasolineras en La Unión varían entre 6,85 y 13,08 metros y que la fuga de gases puede tener impacto en áreas de un radio cercano a los 10 km.
Análisis del proceso de empaque de banano para el aprovechamiento del recurso hídrico mediante la simulación de eventos discretos
Authors: Orozco-Irola Carlos , Badilla-Murillo Félix
Published: September 2022

El recurso hídrico es un elemento esencial para el proceso de empaque de banano y su disponibilidad en algunos sectores está siendo limitada por el aumento en la demanda, agravándose por consecuencias del cambio climático, de ahí que es fundamental una correcta gestión del recurso para asegurar su cantidad, calidad y continuidad de la industria bananera. En esta investigación se analiza el actual consumo de agua de una planta empacadora de banano ubicada en la zona Atlántica de Costa Rica, para determinar las alternativas de diseño y cambios en procedimientos de trabajo que favorezcan su aprovechamiento eficiente y sostenible. Se efectuó una caracterización del proceso de producción a través de un diagrama SIPOC, lo que permitió identificar nueve subprocesos que están directamente relacionados con el consumo y aprovechamiento del recurso. Utilizando los registros de 49 días de proceso, se crearon dos modelos de simulación de eventos discretos, cuya validación muestra, con un 95% de confianza, que no hay diferencias significativas con respecto a los resultados generados por el modelo y los obtenidos del proceso real. Se obtuvo un consumo actual de 96 litros por caja empacada para los días entre semana y de 177 litros por caja empacada para los sábados. Por tanto, aplicando nuevamente los modelos de simulación con las modificaciones en el diseño y procedimientos de trabajo, se estima una reducción de 19% en el indicador para los días entre semana y un 10% para los sábados, representando un ahorro anual aproximado de 44.777,2 m3 de agua.
Plantlia: free android app for measurement of foliar area and color with automated scaling
Authors: Valerio Cubillo Ovidio
Published: September 2022

There is a plethora of apps available for different biological applications, however, mobile software for plant measurement, specifically for field conditions are limited. Additionally, there is a need to create large training datasets for machine learning applications. A free app called Plantlia, which is available to download from the Google Play Store, aims to resolve this with an intuitive interface, and a method to automatically scale images using homography. Plantlia also includes methods to share results from either direct measurements or thresholded images. This paper aims to describe some of the functions of Plantlia, as well as show scenarios that display its performance. Images from cellphones and drone pictures were used for validation on different devices. This is important, as it means that users with low-cost equipment, like drones with no GPS information, can still analyze localized field information. Similarly, researchers can do communal efforts to share and receive in-field data to create machine learning datasets.
Relaciones entre densidad de siembra y variables de rendimiento en pimiento (Capsicum annuum)
Authors: Monge-Pérez José Eladio , Loría-Coto Michelle
Published: September 2022

El objetivo de la investigación fue establecer correlaciones de Pearson en pimiento cultivado bajo invernadero, utilizando dos tipos de poda (española y holandesa), entre la densidad de siembra y las siguientes variables:  número de frutos (por planta y por m2), peso del fruto, y rendimiento total y comercial.  Con poda holandesa las correlaciones entre la densidad de siembra y las variables evaluadas no fueron significativas.  Con poda española se presentaron cinco correlaciones de Pearson con significancia estadística (p≤0,05), en cuyo caso se obtuvieron las regresiones lineales; estas correlaciones fueron entre la densidad de siembra y:  número total de frutos por planta (r=–0,63*); número de frutos de primera calidad por planta (r=–0,87**); número de frutos de segunda calidad por m2 (r=0,61*); rendimiento de segunda calidad (r=0,76**); y rendimiento comercial (r=0,64*).  Se concluye que, con poda española, la mejor opción desde el punto de vista económico es el uso de la mayor densidad de siembra.
Residuos peligrosos de la construcción en Costa Rica y sus impactos al ambiente
Authors: Rosales-Calvo Sheyla María , Abarca-Guerrero Lilliana , Leandro-Hernandez Ana Grettel
Published: September 2022

Históricamente, el sector de la construcción ha sido uno de los contribuyentes más importantes en la economía, ya que genera gran cantidad de empleos durante y después de concluida la obra, creando de esta manera, ingresos y progreso para la economía local .Sin embargo, causa daños ambientales significativos ya que produce una gran cantidad de residuos, algunos de los cuales se consideran peligrosos. A pesar de esto, el país no cuenta con un manejo adecuado de estos residuos, por este motivo, se identificaron los residuos peligrosos del sector de la construcción y su impacto ambiental.
Los datos fueron recolectados por medio de fuentes secundarias, así como encuestas a personal de empresas constructoras, visitas de campo y consultas a expertos. Los resultados demostraron que los residuos peligrosos identificados en la construcción en el país incluyen: ácidos, solventes, detergentes, aditivos para concreto, contenedores de aceite, lubricantes, líquidos de frenos, combustibles, residuos de pintura y sus empaques, desencofrantes, madera tratada con compuestos químicos, residuos de soldadura, silicona y selladores, suelo contaminado, utensilios que contienen productos químicos y tubos fluorescentes. Cada uno de los residuos peligrosos identificados está asociado con un impacto ambiental negativo en el suelo, el agua o el aire. El 100% de ellos tiene efectos negativos en la calidad del agua. A pesar de lo anterior, se encontró que menos del 40% de las empresas encuestadas reutilizan o recuperan para reciclar estos residuos y ninguna de ellas administra adecuadamente todos los desechos peligrosos que generan.
Los datos fueron recolectados por medio de fuentes secundarias, así como encuestas a personal de empresas constructoras, visitas de campo y consultas a expertos. Los resultados demostraron que los residuos peligrosos identificados en la construcción en el país incluyen: ácidos, solventes, detergentes, aditivos para concreto, contenedores de aceite, lubricantes, líquidos de frenos, combustibles, residuos de pintura y sus empaques, desencofrantes, madera tratada con compuestos químicos, residuos de soldadura, silicona y selladores, suelo contaminado, utensilios que contienen productos químicos y tubos fluorescentes. Cada uno de los residuos peligrosos identificados está asociado con un impacto ambiental negativo en el suelo, el agua o el aire. El 100% de ellos tiene efectos negativos en la calidad del agua. A pesar de lo anterior, se encontró que menos del 40% de las empresas encuestadas reutilizan o recuperan para reciclar estos residuos y ninguna de ellas administra adecuadamente todos los desechos peligrosos que generan.
Crecimiento de estructuras de carbono mediante deposición química en fase de vapor a baja presión
Authors: Varela-Fonseca Stephanie Mariela , Hernández-Murillo Camila , Montero-Zeledón Ernesto , Gutiérrez-Fallas Dionisio , Urcuyo Roberto , Puente-Urbina Allen Arturo
Published: September 2022

Los alótropos de carbono han ganado interés en las últimas décadas debido a sus propiedades y a la gran variedad de posibles aplicaciones tecnológicas que han demostrado. Por dichas razones, la obtención de estos alótropos con diferentes propiedades y coberturas es ampliamente investigado. La Deposición Química en Fase de Vapor (CVD, por sus siglas en inglés) es una de las técnicas más utilizadas para obtener este tipo de materiales con una alta calidad y cobertura en una forma controlada. En CVD, se utilizan metales de transición como catalizadores, fuentes de carbono gaseosas y altas temperaturas. En este reporte, se presentan estructuras de carbono sintetizadas sobre substratos de cobre utilizando Deposición Química en Fase de Vapor a Baja Presión (LPCVD, por sus siglas en inglés) con acetileno como fuente de carbono. Los sustratos de cobre se trataron térmicamente bajo una atmósfera reductora de hidrógeno-argón y luego se expusieron a acetileno, variando el flujo de acetileno y el tiempo de deposición. Los materiales resultantes se caracterizaron mediante Microscopía Óptica y Espectroscopia Raman. El enfoque seguido permitió determinar las mejores condiciones de síntesis de grafeno monocapa, de crecimiento irregular.
The Role of Multinational Pharmaceutical Companies in the Battle against COVID-19
Authors: Baykara Sıla Turac , Furfaro Ricardo , Rajput Muhammad Arif , Fernando Jorge Tenorio
Published: September 2022

This research aims to discuss how multinational pharmaceutical companies have responded to the challenges imposed by the COVID-19 pandemic, which would ideally be translated into supplying vaccines in a timely and efficient manner to fight against that emergency. The theoretical approach relies upon the concept of Corporate Social Responsibility (CSR), implying enterprises are supposed to achieve a balance of economic, social, and environmental deliverables while, at the same time, addressing the expectations of both shareholders and stakeholders. The method consists of scrutinizing secondary data—mainly figures of the vaccines provided by the different companies— and qualitative content analysis of the actions they state they have taken, which have been conveyed in press releases and annual reports. The findings show that major corporations have primarily considered the financial aspects of CSR, leaving out the social component they claim to address in their mission statements. Our critical position is that millions of lives could have been saved and relevant economic downturn avoided, particularly in low- and middle-income countries, had there been true practice and implementation of the CSR principles on the pharmaceutical company part.
« L’Ebeb » un Structurant Endogène de Quête de la Longévité et de la Retraite Active en Pays « Lodjukru » (Dabou-Côte d’Ivoire)
Authors: Arnaud Kévin Dayoro Zoguéhi
Published: September 2022

En Côte d’Ivoire, dans un contexte sociodémographique dominé par les jeunes, des institutions traditionnelles subsistent nonobstant la modernisation de la société. Le présent article fait une lecture du fonctionnement de l’institution de « l’Ebeb[1] » dans la société « Lodjukru », dans l’optique de potentialiser les modèles de retraite active. À partir de la méthode descriptive interprétative, du 15 au 27 mars 2020, la ville de Dabou dans le Sud de la Côte d’Ivoire a servi d’espace social de production de neuf (09) récits de vie recueillis auprès de trois (03) femmes et six (06) hommes âgés de 80 à 96 ans. De la mise en sens de ces récits, il ressort que chez les « Lodjukru », la longévité est un concept de production et d’incorporation de leçons biographiques. « L’Ebeb » institutionnalise la valorisation sociale du pouvoir des personnes vieillissantes et rend compte de la domestication sociale de la retraite en Côte d’Ivoire.

 

[1] l’êbéb est une institution de valorisation des aînés dans le pays  Lodjukru Cette institution s’inscrit dans une logique de gestion intergénérationnelle du pouvoir. Elle consacre les efforts individuels et communautaires de la quête de longévité.

Les personnes âgées dont l’âge est compris entre 60 et 68 ans. Celles-ci détiennent le pouvoir exécutif et suprême pendant une période de huit ans non renouvelables.

 

In Côte d'Ivoire, in a socio-demographic context dominated by young people, traditional institutions remain, notwithstanding the modernization of society. This article reads how the « Ebeb » institution works in « Lodjukru » society, with a view to enhancing active retirement models. From the interpretive descriptive method, from 15 au 27 mars 2020, the city of Dabou in the south of Côte d'Ivoire, served as a social space for the production of nine (09) life stories collected from three (03) women and six (06) men aged 80 to 96. From the meaning of these accounts, it emerges that among the «Lodjukru», longevity is a concept of production and incorporation of biographical lessons. The Ebeb institutionalizes the social valuation of the power of aging people and reports on the social domestication of retirement in Côte d'Ivoire.
Influence of Labour Migration on the Rate of Youth Unemployment within the European Union: A Study Review
Authors: Tamar Pkhakadze
Published: September 2022

The European Union has been working on migration issues for several years now and several policies and structures have been developed to better manage processes connected to migration. Legal labour migration remains one of the challenges and is still a very fragmented and limited process. For some specific categories, legal labour migration is much easier, for example, highly qualified workers, seasonal workers, students, researchers, etc. This paper focuses on finding the role of labour migration on unemployment. Paper analysis cases within the European Union and methodologies used are research based on primary or secondary sources (documents, literature). The methods used in this paper are mainly qualitative and include document and text analysis and some case studies. The approach does not refer to the main challenges of migration in the European Union as the labour market does not legally integrate migrants from outside Europe (for example, third-country nationals) and does not legally integrate family members of legally migrated people, asylum seekers or even students studying in the European Union member state.
Possibilities of Nursing High Education in the Context of COVID-19 - Reality and Perspectives
Authors: Machitidze Manana
Published: September 2022

Aim/objective: The Covid-19 pandemic has swept the world and affected our daily life in various ways. While this impact is often negative, it has pushed some areas for development, overcoming challenges, and generating new opportunities. This article reviews the problem, its triggers, consequences, and perspectives. Background: The education sector faced a challenge at the beginning of the pandemic of maintaining security and high-quality teaching simultaneously, especially since there was no online teaching experience. Healthcare faculties were at the forefront of such difficulties, as the training included not only theoretical but also simulation and practical teaching, the implementation of which was initially unimaginable. Design and Methods: The article reviews and describes the global situation through secondary data analyses published in SCOPUS and PubMed from 2020-2022. Also, an analysis of survey results conducting in May 2020 at the University of Georgia (UG) School of Health Sciences. Results and Conclusions: To formulate the main difficulties will be taken list: teaching, research, and communication. Along with education, the challenge was increasing Internet usage, which in many cases led to delays in the teaching-learning process. Creating virtual platforms and developing online pedagogy is undoubtedly a significant pandemic challenge.
Durabilité des Peuplements de Mangrove au Large de la Lagune Ebrié dans les Sous-préfectures de Toukouzou, Jacqueville et Attoutou (Sud de la Côte d’Ivoire)
Authors: Bohoussou Crystel Natacha , Dibi N’Da Hyppolite , Bali Birba Jean-Jacques
Published: September 2022

La présente étude est une contribution à la gestion durable des écosystèmes de mangrove. Elle s’est faite par enquête portant sur l’identification des usages du palétuvier par les populations, la détermination des modes de gestion de la ressource et l’évaluation de la durabilité. Ainsi, une enquête par entrevues dirigées à l’aide d’un questionnaire a été réalisée auprès des populations de 8 localités (Gbehiri, Teffrédji, Tiemien, Avadivry, Niangoussou, Toukouzou, Gboyo et Azagny) au large de la lagune Ebrié. L’analyse descriptive faite des données collectées indique qu’il existe 5 classes d’usage de la mangrove par la population. Il s’agit des usages pour : la fabrication du matériel (8,01%), le bois d’énergie, la médecine traditionnelle (3,87%), la pêche et l’aquaculture (7,44%). La mangrove est au cœur de la vie socioéconomique des populations lagunaires. En effet, il existe trois modes de gestion pour cette ressource. Il s’agit de la gestion traditionnelle par la communauté villageoise, privée pour le propriétaire terrien et la gestion administrative, dans le sciage du site RAMSAR d’Azagny, une restriction sur l’accès à la ressource est imposée par l’office ivoirien des parcs et réserves. Si la population reconnait l’importance de la mangrove, sa gestion n’est toutefois pas faite dans un esprit de durabilité puisqu’aucune action de renouvèlement de la ressource n’est entreprise.

 

            This study is a contribution to the sustainable management of mangrove ecosystems. It was carried out by means of a survey to identify the uses of mangroves by the populations, to determine the management methods of the resource and to evaluate its sustainability. Thus, a questionnaire survey was carried out with the help of guided interviews with the populations of eight localities (Gbehiri, Teffrédji, Tiemien, Avadivry, Niangoussou, Toukouzou, Gboyo and Azagny) off the Ebrié lagoon. The descriptive analysis made of the collected data indicate that there are five classes of use of the mangrove by the population. These are uses for: the manufacture of materials (8. 01%), energy wood, traditional medicine (3.87%), fishing and aquaculture (7.44%). The mangrove is at the heart of the socio-economic life of the lagoon populations. Indeed, there are three management methods for this resource: traditional management by the village community and administrative management, for forest exploitation of the RAMSAR site of Azagny. Here, an access, restriction of the resource is imposed by the Ivorian office of parks and reserves. If the population recognizes the importance of the mangrove, its management is however not made in a spirit of sustainability since no action of renewal of the resource is undertaken.
Landsat 8 oli Satellite Imagery Mapping and Analysis of Bedrock Fracture Networks in the Departments of Yamoussoukro and Toumodi (Central Cote d’Ivoire)
Authors: Guillaume Atte , Arthur Brice Konan-Waidhet , Parfait Sombe Abé , Hervé Jacques Kokobou Kouassi , Jea Biemi
Published: September 2022

This study focuses on the departments of Yamoussoukro and Toumodi located in central Côte d'Ivoire where the problem of drinking water supply is a growing reality. Its objective is to map and analyze the fracturing likely to develop underground aquifers from Landsat 8 OLI data. The set of techniques (color composition, directional and gradient filters) used resulted in the enhancement of linear structures present on satellite images, allowing a better mapping of geological features. The linear map obtained, after the different treatments, is very dense and includes 2063 lineaments. The validation of these different linear structures was made on the basis of the drillings already carried out from the data of the geophysics. The analysis of the fracture networks emphasized two dominant directions, namely: N0°-10° (N-S) and N90°-100° (E-W), which highlights the heterogeneity of the geological formations.  These results constitute an essential contribution to the exploitation of groundwater resources in the departments of Yamoussoukro and Toumodi.
Effectiveness of Neem Oil and Jatropha Oil in Controlling Spodoptera frugiperda (J.E Smith) on Maize in the Republic of Chad
Authors: Josue Mbaidiro Taambaijim’d , Alexis Onzo
Published: September 2022

Upon the evidence of its invasion in Chad in 2018, Spodoptera frugiperda has become a serious threat to maize production, thereby prompting farmers to a massive use of chemical pesticides to reduce its damage. However, given the adverse negative effects of chemical pesticides on human health and the environment, alternatives to chemical control are highly sought. In that respect, the effectiveness of Neem oil and Jatropha oil, two bio pesticides widely acknowledged for their insecticidal properties, was evaluated in the field in comparison with the chemical insecticide, Emamectin benzoate, in a Fisher Blocks design with 4 treatments and 4 replicates. The mean larval density per 25 plants was significantly the lowest (P < 0.0001) on Emamectin benzoate-treated plants(1.13 ± 0.70), followed by Jatropha oil (6.13 ± 0.87) and Neem oil treatments (7.13 ± 0.80) while the highest density was recorded on the untreated plants (12.31 ± 0.87). Similarly, the infestation rates were significantly lower on plots that received the chemical insecticide or the bio pesticides compared to the control plots (P < 0.0001). Foliar and ear damage scores were also significantly lower on the treated than on the control plots (P < 0.0001); and the number of ears attacked was significantly higher on the untreated control than on the other treatments. Maize grain yields were significantly higher in the treated plots compared to the control plots (P < 0.001). Yield gains over the control were 132.57%, 90.91% and 72.73% respectively for Emamectin benzoate, Jatropha oil and Neem oil treatments. It appears, therefore, that the use of Jatropha oil or Neem oil could significantly contribute to an effective and sustainable management of S. frugiperda on maize in Chad, thereby calling for the need for further investigations in that area in the frame of integrated pest management of this pest.
Effets de L’activité Physique sur la Qualité de vie des Diabétiques de Type 2 suivis au Centre Antidiabétique d’Abidjan (CADA)
Authors: Amandine Elodie Niangoran Assoh , Siaka Coulibaly , N’Guessan Kouame
Published: September 2022

L’objectif de la présente étude était d’analyser les effets bénéfiques des exercices combinés d’endurance et de renforcement musculaire sur la qualité de vie des patients diabétiques de type 2. Elle a porté sur 22 sujets diabétiques de type 2 dont 15 femmes et 7 hommes sélectionnés à partir du questionnaire de l'aptitude à l'activité physique (QAAP). Les sujets ont répondu au questionnaire World Health Organization Quality of Life (WHOQOL-26) avant et après un programme de huit (8) semaines d’activité physique combinant les exercices d’endurance et de renforcement musculaire. Les résultats ont montré que l’indice de santé physique est passé de 51,62 à 54,22 soit une augmentation non significative de 2,6 (p=0,091). L’indice de la santé psychologique est passé de 51,13 à 56,62 soit une augmentation non significative de 5,49 (p=0,328). L’indice de relations sociales est passé de 61,74 à une moyenne de 66,28 avec une augmentation non significative de 4,54 (p=0,247). Celle de l’environnement est passé de 51,56 à 54,97 soit une augmentation significative de 3,14 (p=0,008). Nous pouvons conclure que l’activité physique pratiquée sous forme de fitness associant les exercices d’endurance et de renforcement musculaire n'a pas d'effets bénéfiques sur la qualité de vie des patients diabétiques de type 2. En effet, aucune amélioration significative n’a été observée sur les paramètres de la qualité de vie en dehors de l’indice de l’environnement.

 

The objective of this study was to analyze the beneficial effects of combined endurance and muscle strengthening exercises on the quality of life of type 2 diabetic patients. This study involved 22 type 2 diabetic subjects including 15 women and 7 men selected from the Physical Activity Readiness Questionnaire (QAAP). Subjects answered to the World Health Organization Quality of Life (WHOQOL-26) before and after an eight (8) week physical activity program combining endurance and muscle strengthening exercises. The results showed that the physical health index increased from 51.62 to 54.22, a non-significant increase of 2.6 (p=0.091).  The psychological health index increased from 51.13 to 56.62, a non-significant increase of 5.49 (p=0.328).  The index of social relationships increased from 61.74 to a mean of 66.28 with a non-significant increase of 2.6 (p=0.091).  That of the environment index went from 51.56 to 54.97 with to 54.97, a significant increase of 3.14 (p = 0.008). We conclude that physical activity practiced in the form of fitness combining endurance exercises and muscle-strengthening exercises does not have any beneficial effects on the quality of life of type 2 diabetic patients. Indeed, no significant improvement was observed on the parameters of the quality of life apart from the environment index.
The Pengaruh Quick Ratio, Inventory Turnover, Fixed Assets Turnover, dan Assets Turnover terhadap Profitabilitas Perusahaan Sektor Farmasi di BEI Tahun 2016-2018
Authors: Hamdan Umar , Maufiroh Lailatul
Published: September 2022

Perkembangan perekonomian dunia saat ini yang semakin pesat di tandai dengan adanya kemajuan di bidang teknologi dan pertumbuhan inovasi yang secara terus menerus membuat persaingan bisnis semakin kempetitif. Para pelaku bisnis mulai menyadari bahwa kemampuan bersaing tidak hanya terletak pada kepemilikan aktiva berwujud perusahaan, namun lebih pada inovasi, sistem informasi, pengelola organisasi dan sumber daya organisasi yang dimiliki oleh perusahaan. Penelitian ini menggunakan pendekatan kuantitatif. Data yang digunakan dalam penelitian ini adalah data skunder yang diperoleh dari laporan keuangan tahunan, dengan jumlah sampel sebanyak 10 perusahaan dan periode 2016-2018, jadi datanya sebanyak 30. Metode analisis dalam penelitian ini yaitu uji normalitas data, uji autokorelasi, uji heteroskedastisitas, uji multikolinearitas, uji regresi linier berganda, uji hipotesis dan uji koefisien determinasi. Penelitian ini menunjukkan bahwa secara uji F Quick Ratio, Inventory Turnover, Fixed Asset Turnover dan Asset Turnover berpengaruh signifikan terhadap ROA perusahaan sektor farmasi yang terdaftar di BEI periode 2016-2018. Sedangkan secara parsial Quick Ratio, Inventory Turnover, dan Asset Turnover berpengaruh signifikan terhadap ROA perusahaan sektor farmasi yang terdaftar di BEI periode 2016-2018 untuk variabel Fixed Asset Turnover tidak memiliki pengaruh terhadap ROA perusahaan sektor farmasi yang terdaftar di BEI periode 2016-2018.
Analisis Rasio Likuiditas Dalam Mengukur Kinerja Keuangan PT Adira Dinamika Multi Finance Tbk Tahun 2020 - 2021
Authors: Syiffani Karunia , Fatimah Nurul , Janeta Falecia
Published: September 2022

Dalam kajian ini data dikumpulkan dengan 3 metode, yaitu dengan kajian pustaka, non-perilaku observasi berupa annual report yang di publish oleh PT Adira Dinamika Multi Finance Tbk pada tahun 2020 dan 2021, dan penarikan simpulan. Observasi ini bertujuan untuk mengetahui dan mengidentifikasi rasio likuiditas yang dapat berpengaruh terhadap kemampuan PT Adira Dinamika Multi Finance dalam pemenuhan kewajiban keuangan terhadap pihak luar. Berdasar pada hasil perhitungan dapat disimpulkan bahwa pada tahun 2021 rasio lancar (Current Ratio), rasio kas (Cash Ratio), dan rasio pertukaran kas (Turn Cash Ratio) mengalami peningkatan dibandingkan dengan tahun 2020. Rasio lancar meningkat sebesar 2,27%, rasio kas meningkat sebesar 0,12%, dan rasio pertukaran kas meningkat sebesar 1,15%.
Pengaruh Inflasi, Nilai Tukar, dan BI 7 Day Repo Rate terhadap Return Saham pada Industri Barang Konsumsi di Indeks Saham Syariah Indonesia (ISSI) Tahun 2017-2020
Authors: Nisa Khoirun , Sultoni Mohammad Hamim
Published: September 2022

Penelitian  ini  bertujuan  mengetahui  pengaruh  inflasi,  nilai  tukar,  BI  7  Day  Repo Rate terhadap  return  saham  pada  industri  barang  konsumsi  di  Indeks  Saham  Syariah  Indonesia (ISSI) tahun 2017-2020 secara parsial maupun simultan, dengan  menggunakan  purposive sampling,  sampel  yang  digunakan  berjumlah  25  perusahaan,  menggunakan  pendekatan kuantitatif  berupa  data  sekunder,  dengan analisis  regresi  linear berganda  ditemukan  hasil penelitian inflasi, nilai tukar, dan BI 7 Day Repo Rate berpengaruh signifikan terhadap return saham secara simultan maupun parsial
Kemampuan Profitabilitas sebagai Variabel Moderasi antara Corporate Philanthrophy dan Kepemilikan Institusional dengan Nilai Perusahaan
Authors: Masruroh
Published: September 2022

This study aimed to analyze the effect of Corporate Philanthropy and Institutional Owners on the firm value to Profitability as a moderating variable. This study using a secondary data. The population of this research are the manufactured companies listed on Indonesia Stock Exchange during the years 2014-2018. The sampling method using is purposive sampling method. Based on the criteria using, the company qualified research sample is 22 companies. The analysis method using in this study is Moderating Regression Analysis, model feasibility test and t-test.  Based on f-test, Corporate Philanthropy, Institutional Owners, and Corporate Philanthropy and Institutional Owners that is moderated Profitability significant effect to firm value. Based on t-test, Corporate Philanthropy doesn’t significant effect to firm value, Institutional Owners doesn’t significant effect to firm value, Corporate Philanthropy that is moderated Profitability doesn’t significant effect to firm value, while Institutional Owners has a negative and significant effect to firm value
PHYSICAL ACTIVITY LEVEL RESTORATION IN PATIENTS AFTER ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION USING «BONE-TENDON-BONE» AUTOGRAFT
Authors: Suchilin I. A , Malanin D. A , Volodin I. V. , Julikov A. L , Cherezov L. L
Published: September 2022

Injuries to the anterior cruciate ligament of the knee joint, while remaining one of its most common types of injury, cause restriction of physical activity in people leading an active lifestyle, due to the occurrence of biomechanical disorders. The generally accepted approach of surgical correction is aimed at replacing the lost structure in order to approach the motor norm of the preserved elements of the joint. The presented publication reflects the results of arthroscopic surgical reconstruction of the anterior cruciate ligament with an autograft from the patellar ligament by anatomical and transtibial methods. The main methods of diagnosing tears of the anterior cruciate ligament were clinical and instrumental studies, including manual testing, radiography, magnetic resonance imaging, hardware arthrometry. A total of 134 patients with long-standing damage to the anterior cruciate ligament and chronic anterior instability of the knee joint were treated, which were divided into two groups according to the method of plastic surgery. Complete recovery of the level of physical activity and return to sports were observed in the majority of patients of both clinical groups.
INFLUENCE OF BASIC AND EXTRACORPOREAL THERAPY ON THE LEVEL OF THYROID HORMONES AND ANTITHYROID ANTIBODIES IN PATIENTS WITH RHEUMATOID ARTHRITIS WITH THYROID INVOLVEMENT
Authors: Rusanova O. A , Trofimenko A. S , Emelyanova O. I
Published: September 2022

Objective: to study the effect of treatment on the dynamics of antibodies to thyroid hormones in patients with rheumatoid arthritis with thyroid involvement. Methods: 27 people were selected with a diagnosis of rheumatoid arthritis, with a different cjndition of thyroid gland, tread with basic therapy (methotrexate or leflunomide). The patients were divided into three groups, depending on additional anti-inflammatory therapy: group 1 - NSAIDs, group 2 - NSAIDs and glucjcjrticoids (GC), group 3 - NSAIDs, GC and plasmapheresis (7, 15 and 5 patients, respectively). Concentrations of TSH, T3 and T4 were measured using ELISA, antibodies to T3 and T4 - by indirect ELISA using antigens immobilized on magnetic polyacrylamide beads. Marker levels were measured at admission to the hospital and at the time of discharge. Results. By the end of hospitalization of RA patients with autothyroid pathology in the hospital, there was a significant decrease in the content of antibodies in the blood to thyroid hormones. The level of antibodies to thyroid hormones in RA patients with concomitant autothyroid pathology demonstrated significant differences between the indicators before and after treatment in patients in the third group. The levels of antibodies to thyroid hormones in subgroup No. 3 after treatment significantly decreased by 75 % from the initial values. The other two subgroups also showed reductions in antibody levels, but these were not statistically significant. Conclusion. Thus, the basic therapy of RA, as well as additional methods of reducing RA activity using NSAIDs, GC, plasmapheresis, can affect the levels of thyroid hormones in patients with thyroid lesions. The most pronounced effect on the concentration of antibodies to thyroid hormones was found in patients who received a course of plasmapheresis in addition to other methods of treatment. T4 level after treatment was proportionally reduced in patients of all three groups, while remaining within the normal range. For T3, there were no distinct dynamics after treatment. The results obtained indicate a predominantly autoimmune genesis of thyroid lesions in RA.
MODERN ASPECTS OF THE COURSE AND METHODS OF PREVENTION OF RECURRENT URINARY TRACT INFECTIONS IN PRESCHOOL GIRLS
Authors: Shaposhnikova N. F , Salomatina O. S
Published: September 2022

Urinary tract infections in children are increasingly attracting the attention of specialists, which is due to their wide spread, high recurrence rate, are widespread, have a serious prognosis and require the search for the earliest diagnosis, optimization of therapy and prevention of exacerbations. The article provides a retrospective analysis of the medical histories of children undergoing inpatient treatment in the nephrological department of the state healthcare institution «Children's Clinical Hospital 8»,Volgograd in order to analyze the grounds for choosing preventive therapy schemes with the possibility of further catamnestic evaluation of the effectiveness of prevention. According to the results of the analysis, the prevalence of therapeutic dosage prescriptions of furazidine and nitroxoline was revealed.
APPLICATION OFAN EXTENDED SET OF EXCITATION/EMISSION WAVELENGTHS INTHE DETECTION OF FLUORESCENTADVANCED GLYCATION END-PRODUCTS, FORMED BOTH INVITRO AND IN VIVO
Authors: Litvinov R. A , Ibragimova U. M , Rzayeva A. S , Sokolova E. V. , Shushakova A. I , Valuyskiy N. V.
Published: September 2022

Using a set of excitation/emission wavelengths characteristic of fluorescent advanced glycation end-products (AGEs), the fluorescence intensities of glycated albumin and hydrolyzed diabetic rat tail tendons were compared. The following excitation/emission wavelengths were used: 335/385 nm, 345/405 nm, 370/440 nm, 379/463 nm and 440/520 nm. The ability of 1-benzyl-1,4-dihydronicotinamide (a fluorophore) to interfere with fluorescence of AGEs was studied. It was shown that glycated albumin and hydrolyzed tendons of diabetic animals have nearly identical values of fluorescence at all wavelengths. At the same time, 1-benzyl-1,4-dihydronicotinamide, which was added into the samples of glycated albumin to bring the interference (the addition was carried out after the end of glycation reaction), interfere only at the excitation/emission wavelengths of 370/440 nm and 379/463 nm. Thus, the advantage of the use of entire set of the wavelengths (simultaneously) for AGEs detection was confirmed. We believe that the usage of the entire set of wavelengths may reduce the risk of interference-induced errors in detection of fluorescent AGEs.
THROMBOSIS OF THE LEFT ILIAC ARTERY IN COVID-19: A CLINICAL CASE
Authors: Petrova O. V , Tverdokhlebova D. K , Shashin S. A , Nikulina D. M , Tarasov D. G
Published: September 2022

The incidence of arterial thrombosis in patients with COVID-19 is about 11 %. Currently, the pathogenesis of these complications has not been fully studied. Purpose: present the course of COVID-19 Associated thrombosis of the left iliac artery on a clinical example. Material and methods. Patient with Covid-19 developed thrombosis the iliac artery. Results. A clinical example demonstrates that a patient with risk factors - coronary heart disease, type 2 diabetes mellitus, obesity, smoking, against the background of a new coronavirus infection, an iliac artery thromboembolism developed. Conservative treatment of thrombosis with antithrombotic drugs was not successful. In this connection, the patient was hospitalized in a socialized medical institution, where a thromboectomy was performed from the iliac, femoral, popliteal artery on the right. The patient's condition improved during the therapy. However, on the 3rd day, a pneumonia clinic developed, which was the reason for transferring him to a covid hospital. Despite the etiotropic and antithrombotic therapy, repeated arterial thrombosis of the vessels of the lower limb progressed, which required surgical intervention (amputation of the lower leg). The cause of death of the patient was a progressive multiple organ. A clinical example shows that the pathogenesis of thrombosis in COVID-19 has not been fully studied (not established), and treatment regimens with antithrombotic drugs require further revision.
THE EFFECT OF VISCERAL OBESITY ON THE CONDITION OF THE MAIN ARTERIES IN PATIENTS WITH CHRONIC HEART FAILURE
Authors: Statsenko M. E , Fabritskaya S. V , Ryndina Yu. A , Shilina N. N
Published: September 2022

Aim: to study the relationship between the severity of visceral obesity and the condition of the main arteries in patients with chronic heart failure (CHF) with obesity. Materials and methods. 116 patients with CHF of stage I -IIA of functional class I -III (FC) aged 40 to 65 years were included. All patients were divided into 3 comparable groups: group 1 included patients with CHF with normal body weight (n = 34), group 2 - overweight CHF (n = 40), group 3 - CHF and 1 - 2 degree obesity (n = 42). There were no differences in severity, CHF FC and NT-proBNP levels between the study groups. A clinical examination was performed, indicators of visceral obesity and adipokine status were evaluated. Arterial stiffness was assessed by measuring the pulse wave propagation velocity (CWPV) through the vessels of muscular (CWPVm) and elastic (CWPVe) types. Results. A high percentage of visceral obesity was found: 17.6 % among people with normal BMI, 70 % among overweight people and 100 % among obese people. A statistically significant increase in CWPVe was found in patients with CHF and obesity in comparison with patients with CHF and normal body weight (10,5 [8,9; 11,6] vs 8,5 [7,5; 8,4] m/s). CWPVe > 10 m/s was significantly more common among overweight or obese patients compared to patients with normal body weight (62,4 and 83,2 % vs 37,5 %, respectively). There was a significant decrease in the concentration of adiponectin and an increase in the level of leptin from group 1 to group 3. The correlation analysis showed the presence of reliable relationships between the parameters characterizing the elasticity of the vascular wall and the severity of visceral obesity, as well as laboratory markers of obesity. Conclusion. The data obtained indicate a negative effect of visceral obesity, hyperleptinemia and hypoadiponectinemia on the condition of the main arteries in patients with CHF.
Socio-political features and prospects for the development of the Russian movie industry through the prism of the history of soviet cinema and international film industry experience
Authors: Tumanov Arseniy
Published: September 2022

The article is devoted to the Russian movie industry and the problems that national cinema is currently facing. This applies to surface level, urgent difficulties, such as the rapid decline in cinema attendance in the absence of Hollywood tentpoles at the box office, as well as to deeper shortcomings, among them the lack of Russian cinema's own identity. The author describes how the modern system of state support of the movie industry unwittingly leads to a deluge of similar run-of-the-mill movies, which not only negatively affects the total revenue of Russian cinemas, but also does not allow the domestic film market to grow, as well as effectively perform its socio-political functions. Patriotic high-budget blockbusters have become the most demanded type of Russian film production in recent years, the plot of which is based on events from Russian history, told in the language of Western commercial cinema. The rare but nevertheless sound successes of such films have led to the system under which these types of movies receive the lion's share of budget funding. Disregarding the fact that box office data shows that viewers are more often attracted to films of a smaller scale, but about lives of our contemporaries of today and tomorrow. The current situation in the Russian movie industry is compared with the experience of the formation of the Soviet cinema and withe the development of national film industries of China, South Korea and France.
Rethinking attitudes towards education in the cultural space of young people
Authors: Sorokin Oleg
Published: September 2022

In the cultural space of young people, the rethinking of attitudes towards education is accompanied by the emergence of hybrid patterns that combine opposite meanings. From the perspective of normative approach these patterns should be considered as opposing value-normative patterns, standards of social interactions in the field of education. The paper considers the nature of youth deviant behaviour in the context of deviation from the underlying meanings that have been incorporated into the understanding of moral and ethical standards within the dominant culture. Young people's choice in favour of deviant meanings is presented as a consequence of intensified instrumentalisation and rationalisation of youth in the educational sphere. The results of the All-Russian study conducted by the Centre of Sociology of Youth ISPI FNISC RAS in 2020 are presented. The relationships between the level of education, place of study, value of education and deviant meanings in the cultural space of youth are analyzed, which allows to investigate the semantic orientation of self-regulation of deviant behavior of youth in the educational sphere. The findings of the study suggest that the increasing instrumentalization of knowledge and cultural practices in education reinforces the processes of rethinking the essence of social norms in the social reality of youth. This rethinking manifests itself at two poles of rationalization: from the liberalization of these norms to the almost complete leveling out of former standards of interaction.
Social Justice in the Collective Perceptions of the Population of the Regions of the South of Russia in the Context of the Formation of the All-Russian Identity
Authors: Volkov Yuriy
Published: September 2022

The article is devoted to an overview analysis of the results of the research project “Social justice in ensuring the harmonization of interethnic relations and strengthening the all-Russian identity of the population in the South of Russia”, The data obtained during the work on the project are considered in the context of the problem of forming a unified all-Russian civic identity, which sets a specific angle for analyzing the responses of respondents reflecting the collective ideas of the population of the regions of Southern Russia about social justice. The specificity of the chosen approach to the study is determined by the fact that the study of ideas about justice in the mass consciousness is carried out through the prism of interethnic relations in the regions of Southern Russia, which makes it possible to identify and assess the state of the process of formation of all-Russian identity in ethnic groups living in the South of Russia, the presence and level of severity of interethnic contradictions. The author of the article shows, based on empirical data obtained in the course of the study, that interethnic relations in the southern regions of Russia currently have a generally positive character, the ethnic factor is not an object of politicization, in the representation of ethnic groups there are social opportunities and legal responsibility, which indicates the emerging priority of the emerging all-Russian civic identity in relation to ethno-group identities. At the same time, it is emphasized in the article, fairness in interethnic interactions is assessed by respondents mainly by the criterion of the absence of preferences from the local authorities in relation to a particular ethnic group when solving issues of everyday socio-economic life, creating equal opportunities for intergenerational reproduction and broadcasting of ethno-cultural identities.