bluuebunny/crossref_metadata_2025 huggingface dataset:
ASSOCIATION OF TNF AND LTA GENES WITH ATHEROSCLEROSIS COMPLICATIONSIN PATIENTS WITH HISTORY OF ACUTE CORONARY SYNDROME
Authors: Zateyshchikov D A , Pushkov A A , Nikitin A G , Brovkin A N , Evdokimova M A , Baklanova T N , Tereschenko S N , Dzhaiani N A , Akatova E V , Glezer M G , Galyavich A S , Koziolova N A , Yagoda A V , Boyeva O I , Horolets E V , Shlyk S V , Volkova E G , Konstantinov V O , Nosikov V V , Blagodatskih K A
Published: March 2018

The aim of this study was to investigate an association of polymorphic markers G(-308)A of TNF gene and Thr26Asn of LTA gene with the frequency of poor outcomes in patients with the history of acute coronary syndrome.Methods. A total of 1145 patients admitted to cardiological hospitals of Moscow, St. Petersburg, Kazan, Chelyabinsk, Perm, Stavropol, and Rostov-on-Don with ischemic heart disease exacerbation were examined. The maximum follow up time was 3.2 years. The identification of polymorphic marker allele was carried out by hybridization-fluorescent analysis using real-time polymerase chain reaction.Results. In case of Thr26Asn polymorphic marker of LTA gene we have not found any association with the frequency of poor outcomes in patients with the history of acute coronary syndrome. However, in case of G(-308)A polymorphic marker of TNF gene we have found the reliable association. The carriers of GA and AA genotypes has higher frequency of poor outcomes in comparison with the carriers of GG genotypes. The survival time to the endpoint for carriers of the GA and AA genotypes was 43.3 months (95% CI = 40.04 - 46.56) vs. 49.6 months (95% CI = 47.38 - 51.82) for carriers of theGG genotype (χ2 = 15.4; р < 0.001).The results of our study allow to make a conclusion that the G(-308)A polymorphic marker of TNF gene is significantly associated with hereditary predisposition to unfavourable outcome in patients with history of acute coronary syndrome.
PRE-OPERATIVE THERAPEUTIC PREPARATION FOR PATIENTS IN ONCOSURGERY
Authors: Shestopalova I M , Laktionova L V
Published: March 2018

The paper deals with current possibilities of pre-operative therapeutic assessment and the management of patients with concurrent cancer and cardiac diseases.Adequate diagnostics, modern surgery and therapeutic methods in pre- and postoperative period allow to survive 12 months without features of both diseases in 68.4% of patients. 3-5 year survival rate is respectively 25.8-12.9%.
EXPERIENCE IN HYBRID SURGERY FOR COMBINED LESIONS OF BRACHIO-CEPHALIC ARTERIES AND THORACOABDOMINAL AORTIC ANEURYSM
Authors: Chupin A V , Shablovsky O R , Zaytsev M V , Deryabin S V , Kolosov R V , Lesnyak V N , Nishchenko A V , Starkova E V
Published: March 2018

We presented the case history of successful surgical treatment of patient with aortic arch aneurysm, thoracoabdominal aortic aneurysm and stenosis of brachiocephalic arteries. She was underwent hybrid reconstruction (open and endovascular intervention): open reconstruction of both carotid bifurcations and the right subclavian artery and arc and descending thoracic aortic endoprosthesis.
CYTOKINE PROFILE IN PATIENTS WITH ADENOVIRAL INFECTION
Authors: Shipilov M V , Ivanov V V
Published: March 2018

Investigated the serum of patients with adenoviral infection (n = 17). Changes of cytokine circuit in a significant increase in the acute period of disease IFN-γ, IL-1ra, IL-4, IL-6, IL-8, IL-10 and IL-17. Period of convalescence marked by high levels of IFN-γ, IL-4, IL-10, IL-17.
SYNDROME OF CHRONIC ABDOMINAL ISCHEMIA IN THE PRACTICE OF GENERAL SURGEONS
Authors: Ivanov Yu V , Chupin A V , Sazonov D V , Lebedev D P
Published: March 2018

One possible cause of resistant abdominal pain syndrome is a chronic intestinal ischemia caused by varying degrees of occlusion of the mesenteric vessels. Due to the variety of clinical manifestations, just noticeable their specificity and lack of awareness of general practitioners timely diagnosis of the syndrome of chronic abdominal ischemia is difficult. The main methods of diagnosis at this stage are: ultrasound duplex scanning, spiral computed tomography, magnetic resonance computed tomography angiography in the mode of indirect and direct angiography. The method of choice of surgical treatment is percutaneous transluminal angioplasty and stenting of the arteries.
THE POSSIBILITY OF MINIMALLY INVASIVE ROENTGEN-SURGICAL TECHNIQUES IN ABDOMINAL SURGERY
Authors: Ivanov Yu V , Lebedev D P , Alekhnovich A V
Published: March 2018

The clinical observations showing the diagnostic and therapeutic capacities of minimally invasive percutaneous roentgen-surgical techniques in the diagnosis and treatment of hepatopancreatoduodenal zone diseases are presented. In these cases, the use of minimally invasive surgical techniques on various stages of diagnosis and treatment have helped to correct diagnosis, and effective treatment, discarding traditional traumatic surgery. In the first clinical observation percutaneous radiosurgical method drainage of an abscess of the liver allowed to reveal chronic form of fascioliasis and conduct specific treatment. In the second - to establish the cause of recurrent subhepatic abscess, in the third-to remove concrements of common bile duct, if unable to perform open surgery or endoscopic papillosfinkterotomiya and remove concrements. Common to all three clinical observations is the fact that up to minimally invasive roentgen-surgical methods of treatment were carried out public activities, which for various reasons proved ineffective. The latest minimally invasive radiosurgical methods allow not only to establish an accurate diagnosis, but may be intermediate or final treatment.This is especially important in severe patients at impossibility of the surgery and if necessary, stabilization of the general status and improving metabolic and functional parameters of the upcoming radical operation. In most cases, a variety of minimally invasive surgical techniques are not competing among themselves, but only complement or substitute one another in every concrete clinical situation.
THE SAFETY OF MESENCHIMAL STROMAL CELLS THERAPY
Authors: Knyazev O V , Konoplyannikov A G , Parfenov A I , Ruchkina I N , Churikova A A , Albulova E A , Bykova S V , Boldyreva O N , Fadeeva N A , Lishinskaya A A , Bondarenko E Yu , Kagramanova A V
Published: March 2018

There is a large amount of literature data that shows the effectiveness of cell therapy using mesenchymal stromal cells (MSCs), as on preclinical models and in some clinical studies in small groups of patients.Currently the use of MSC in clinical practice is limited by security considerations. Potential risks associated with their proliferative capacity, the risk of infectious complications, as well as the possible immunogenicity of the cells themselves.Foreign researchers analyzed on the basis of a literature review, the results of which evaluated the clinical safety of MSCs. The article presents the results of our monitoring of patients with inflammatory bowel disease (IBD), which received MSCs in the Department of pathology bowel. The results of our study, and the results, given in the review, should provide scientists and policy-makers the confidence that according to available scientific data an innovative method of cell therapy is safe for clinical use.
SUDDEN CARDIAC DEATH AND WOLFF-PARKINSON-WHITE ELECTROCARDIOGRAPHIC PATTERN: A REVIEW
Authors: Mamchur S E , Ardashev A V
Published: March 2018

The causes of sudden cardiac death in patients with Wolff-Parkinson-White syndrome are considered; necessity of endocardial electrophysiological study and radiofrequency catheter ablation is discussed, including asymptomatic patients with accessory pathways.
MRI-ASSESSMENT OF COMPOSITE INTERFERENCE SCREWS AFTER RECONSTRUCTION OF THE ANTERIORCRUCIATE LIGAMENT
Authors: Dzhambinova E A , Zvezdkina E A , Akhpashev A A , Agzamov D S , Lesnyak V N
Published: March 2018

In the article authors describe the results of MRI studies of patients after reconstruction of the anterior cruciate ligament. The potential of biodegradable implants, timing of their location in the bone. The evaluation of bone response to biodegradable screws. The authors defined the terms of biodegradation clips from polylactic acid polymer and tricalcium phosphate.
THE EXPERIENCE OF USE OF CERAMIC-POLYETHYLENE PROSTHESES IN TOTAL HIP ARTHROPLASTY
Authors: Turahodzhaev F A , Zagorodnii N V , Magomedov H M , Kalashnikov S A
Published: March 2018

From 2004 to 2014 there were conducted more than 400 operations with the use of ceramic- polyethylene prostheses in the Hospital №13 (clinical base of the Department of Traumatology and Orthopedics of Peoples’ Friendship University of Russia). In any case there were no signs of aseptic loosening of prosthesis components. Nowadays the use of low friction ceramic-polyethylene friction pair in hip arthroplasty is widespread for most patients with hip joint pathology in all age groups.
EARLY BREAST CANCER. THE CONTROVERSY OF BREAST CANCER IN SITU
Authors: Kosyi V V , Kedrova A G
Published: March 2018

Perfecting screening tests of breast cancer by introducing digital mammography has increased findings the initial stages of the growth (neoplasma) in situ up to 25% of all detected cases of breast cancer. It has lead to 98% of surgical or combined forms of treatment although the risk of the advance into intrusive cancer is observed only in 50% to 75% of patients. In this connection the search for the prognosis marker and the degree of the radicalism of the treatment of such patients is the most discussed questions on clinic forums. This article discusses the re-thinking of the problem of the initial stages of breast cancer and working-out the best possible approach to its treatment.
Algorithm of oNe-stAge correctioN oF breAst Asymmetry iN PAtieNts with hyPomAstiA
Authors: Sharobaro V I , Baeva A A , Mokshina N V
Published: March 2018

We analyzed the results of one-stage correction of the asymmetry of mammary glands in 51 patients with a diagnosis of hypomastia. On the basis of obtained results the algorithm of one-stage restoration of symmetry at the given category of patients, based on the type and severity of the asymmetry was developed, which contributes to the achievement of good aesthetic results in 94.1% of cases.
STUDY OF THE PLATELET-RICH PLASMA CLINICAL EFFICACY IN THE TREATMENT OF KNEE OSTEOARTHRITIS
Authors: Lazishvili G D , Egiazaryan К A , Akhpashev A A , Danilov M A , Strakhov M A , Gaev T G
Published: March 2018

The study of platelet-rich plasma efficacy in the treatment of patients with knee osteoarthritis (OA) was performed. 188 patients were included and divided into three groups. Group 1 - 82 patients with OA, where hyaluronic acid was used for treatment, Group 2 - 36 patients, and Platelet Rich Plasma (PRP) and hyaluronic acid were used, Group 3 - 70 patients, only PRP was used. It`s been found that the use of PRP for treatment is characterized by a pronounced clinical efficacy compared with use of hyaluronic acid, which manifests in reduced detection rate of edema, hyperthermia and hyperemia. The use of PRP leads to pain reduction in the knee joint and increase the functionality of patients, that confirmed by more pronounced declining of visual analog scale indicators, Leken index and the WOMAC index values increase. The presented results of study are consistent with authors who believe that the lack of side effects and complications when using PRP indicates the safety of its use in clinical practice.
THE ORGANIZATION OF TUBERCULOSIS CHEMOPREVENTION OF HIV INFECTED PEOPLE IN MODERN CONDITIONS
Authors: Sinitsyn M V , Ausheeva L B , Bogorodskaya E M
Published: March 2018

In connection with the growing number of patients with combined HIV/ TB infection the legal framework and organization of treatment for such cases need some modernization. We investigated the legal documents regulating the provision of TB care in the Russian Federation, and medical care for HIV-infected persons. The results have shown that there is no comprehensive program for the reception, inspection and simultaneous antiretroviral therapy, tuberculosis chemoprevention and timely tracking the development of unwanted side reactions in patients with combined HIV/ TB infection. Therefore, for effective work on the prevention and early detection of tuberculosis the integration of TB and AIDS Service Center is required. Chemoprevention schemes, including optimally two medicines in complex, especially if patients on antiretroviral therapy, are also considered.
OXYGEN UPTAKE OF BLOOD IN PATIENTS WITH ISCHEMIC HEART DISEASE AFTER MYOCARDIAL REVASCULARIZATION
Authors: Bondarenko E T , Iljyn M V , Zotov A S , Staroverov I N
Published: March 2018

Oxidative stress, which is observed in patients with coronary artery disease (CAD), is accompanied by the changes of plasma redox regulation. We aimed to investigate the dynamics of blood oxygen uptake rates in patients with CAD following coronary artery bypass graft surgery. We examined 80 CAD patients at admission to the hospital, discharge and 6 months after surgery. Patients were divided into three groups: Group 1 - 8 patients with acute coronary syndrome (ACS), Group 2 - 61 patients with old myocardial infarction (old MI), Group 3 - 11 patients with chronic CAD (CCAD). 24 healthy donors were included in the control group. We modelled the processes of lipid peroxidation (LPO) in plasma using biological oxygen monitor. The increase of indicators of blood oxygen uptake was registered in ACS and old MI patients at the day of admission, old MI patients at the day of discharge from the hospital, and CCАD patients at the day of 6 months after surgery. The increase of these indicators occurred after the depletion of blood antioxidant systems and caused by activation of lipoprotein peroxidation on the minute 30 and the decline of lipid radicals formation on the minute 40. As the plasma antioxidant status was greater, the оxidative damage of lipids started on the minute 40 of the study.
THE USE OF DIODE LASER IN THE TREATMENT OF HEMORRHOIDAL DISEASE
Authors: Gigin N K , Sarkisyan Yu G , Potapova Yu V , Ivanov Yu V
Published: March 2018

The study focuses on modern and innovative methods of surgical treatment of hemorrhoidal disease. The results of using diode laser in the treatment of this disease showed some effectiveness and potential of this methodology. Identified key indications for the use of the diode laser, the technique of execution, revealed its advantages over traditional methods of surgical treatment.
THE QUALITY OF LIFE IN PATIENTS WITH CORONARY HEART DISEASE
Authors: Zholkovsky A V , Ermolenko V V , Borondzhiyan T S , Timofeeva L L , Chubarov V E , Urusov I A
Published: March 2018

Occlusion of terminal aorta is mostly often caused by atherosclerosis and the development of lower limb ischemia requires prompt treatment. In addition to the open aortic surgery recanalization and stenting can also be used. The article presents the first experience of endovascular treatment in patients with good immediate and mid-term results. This method is suitable to use in patients with contraindications to general anesthesia.
CLINICAL CASE OF SURGERY KIDNEY CANCER WITH TUMOR THROMBUS IN THE ATRIUM AND ISOLATED LIVER METASTASIS
Authors: Perepechay V A , Zholkovsky A V , Burikov M A , Makhno Yu E , Spitsyn I M , Siryak A V
Published: March 2018

Presents a clinical case of successful surgical treatment of kidney cancer with tumor thrombus of the inferior vena cava (IVC) to the level of the atrium, with simultaneous resection of segment I of the liver containing a single metastasis, in 57-year patient.
SERUM OSTEOPONTIN LEVEL IS ASSOCIATED WITH PRESENCE OF ATRIAL FIBRILLATION IN CALCIFIC AORTIC VALVE STENOSIS
Authors: Tipteva T A , Chumakova O S , Reznichenko N E , Safaryan V I , Baklanova T N , Voloshina N M , Zateyshchikov D A
Published: March 2018

Identification of risk factors associated with presence of atrial fibrillation (AF) in patients with aortic valve stenosis (AS) remains to be unraveled.The aim of the study was to investigate relationship between profibrotic biomarkers and presence of AF in AS patientsMethods. 191 patients (29,8% male, 77,7±0,59 years) with AS (defined as aortic valve area (AVA) ≤ 2,0 sm2) were enrolled in the study. Clinical, echocardiographic and biochemical variables, including serum TGFβ1 and osteopontin levels were compared between 2 groups of patients: with and without AF. Results. 83(36,5%) of AS patients had AF. In logistic regression models independent associations between AVA index (p=0,040), left atrial volume (p=0,021), OPN (р=0,009) and presence of AF were found. Patients with serum OPN level > 10,05 ng/ml had twice more higher AF incidence comparedto patients with serum OPN level ≤ 10,05 ng/ml (53,8% and 29,2%, respectively, p=0,020).Conclusion. Serum OPN level was independently associated with presence of AF in AS patients, thus we speculate on it’s predominant profibrotic role in the left atrium.
EFFICIENCY AND SAFETY OF RADIOFREQUENCY CATHETER ABLATION OF ATRIAL FIBRILLATION IN ELDERLY PATIENTS
Authors: Fedorova M H , Chapurnykh A V , Nizhnichenko V B , Lakomkin S V , Doshicin V L
Published: March 2018

Atrial fibrillation is one of the most frequent and significant rhythm disturbances. The effectiveness and expediency of using one of the most effective methods of treatment of this arrhythmia (radiofrequency ablation in elderly patients) remains a controversial and insufficiently studied issue. The article compares the results of the treatment of 63 patients of mature age (up to 75 years) and senile age (from 75 years). Patients underwent 78 operations of radiofrequency catheter ablation of atrial fibrillation and atypical atrial flutter, which was resistant to drug therapy. In the groups of patients of mature and senile age, there were no statistically significant differences in the effectiveness of treatment. In elderly people group, a higher incidence of complications was found mainly due to hydrothorax, but these complications did not increase the risk of death and were stopped during treatment. This allows to conclude that the senile age of patients should not be the reason for refusing to conduct radiofrequency catheter ablation.
THE PROBLEM OF HEART TRANSPLANT REJECTION AND WAYS OF OPTIMIZING THE ASSESSMENT OF ENDOMYOCARDIAL BIOPSY RESULTS
Authors: Stavenchuk T V , Kosmachova E D , Shelestova I A , Slavinsky A A , Terman E A , Verevkin A A , Medvedeva L A , Barbuhatty K O , Tatarintseva Z G , Porchanov V A
Published: March 2018

The following article describes tactics of recipient management when a rejection episode of a heart transplant is being suspected. We have discovered some new figures to assess biopsy samples through computerised morphometric study, which can both improve and clarify biopsy results. CD3+ (T-cells) and CD 68+ (macrophages) figures make it possible to determine the extent of transplant rejection in accordance with the International Society for Heart and Lung Transplantation diagnostic criteria (sensitivity 91%, specificity 91%).
ANTI-HYPERTENSIVE EFFECT OF RENAL ARTERIES RADIOFREQUENCY DENERVATION IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION
Authors: Gapon L I , Mikova E V , Savel`eva N Yu , Kopylova L N , Aleksandrovich E L
Published: March 2018

Objective. To assess the effect of some characteristics of chronic obstructive pulmonary disease (COPD) in patients after elective percutaneous coronary intervention (PCI) on repeat myocardial revascularization frequency in long-term period (up to 3 year). Materials and methods. 135 patients with COPD, who suffered stable ischemic heart disease and were underwent PCI, were included in prospective observational study. Follow-up duration was up to 3 year. Evaluation included comparing the frequency of elective repeat revascularization in regards to frequent COPD exacerbations, COPD severity, lung function and C-reactive protein (CRP) plasm level. Comparing Kaplan-Mayer curves and Cox regression analysis were also applied. Results. Elective repeat myocardial revascularization frequency was 23% and 2,1 times higher among the patients who had frequent COPD exacerbations history (95% CI 1,1-3,9). The difference between Kaplan-Mayers curves was also detected as statistically significant (p=0,016). None of the pulmonary function characteristics had relations with elective repeat revascularization frequency increase. Frequent COPD exacerbations history and CRP plasma level were included in Cox regression model as non-cardiovascular variables (p=0,05 and 0,08 respectively). Conclusions. Frequent COPD exacerbations history and increased CRP plasma level are independent non-cardiovascular variables related to increased risk of elective repeat myocardial revascularization. None of the pulmonary function characteristics had relations with elective repeat revascularization frequency increase.
CORONARY ANGIOGRAPHY IN PATIENTS WITH PREMATURE ACUTE CORONARY SYNDROME AND FAMILY HYPERCHOLESTEROLEMIA
Authors: Averkova A O , Brazhnik V A , Koroleva O S , Zubova E A , Sizgunov D S , Rogozhina A A , Zateyshchikov D A
Published: March 2018

Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder with a prevalence of 1/200-1/500 in the general population. The aim of the study was to assess the specific features of coronary angiography in young patients with acute coronary syndrome (ACS) and FH diagnosed using Dutch Lipid Clinic Network (I) and Simone Broome Register (II) criteria. 224 pts with early onset of ACS who underwent coronary angiography were selected (≤ 55 years of age for men and ≤ 60 years of age for women). Two, three vessel disease/left coronary artery (LCA) impairment was observed in 12 of 13 (92,3%) pts with definite/possible FH (I, p=0,036) and in 28 of 29 (96,6%) pts with probable FH (II, p=0,001). In patients with family history of cardiovascular disease three ves-sel disease or LCA impairment was observed in 54 of 73 (74%) pts (p=0,024). Comparing two groups of patients with LDL over and below 4,6 mmol/l (the concentration was obtained by ROC analysis) it was shown that 20 of 29 (69%) and 58 of 144 (40,3%) pts (p=0,036) respectively had culprit vessel thrombosis. Thus, we can suppose that in pts with higher LDL level atherosclerotic plaque rupture is observed more frequently in case of ACS. Therefore, it has been shown that multivessel and LCA stem impairment in young patients with ACS and FH is associated with both main factors used for not genetic FH diagnosis: high LDL cholesterol level and family history of cardiovascular disease.
PCSK9: BIOLOGICAL ACTIVITY REGULATION AND CONNECTION WITH LIPID AND CARBOHYDRATE METABOLISM
Authors: Averkova A O
Published: March 2018

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease which plays an important role in the regulation of LDL receptor (LDLR) expression and apolipoprotein B (apoB) lipoprotein cholesterol metabolism. It is well known that hepatic PCSK9 expression, its activity and secretion influence cholesterol homeostasis. An upregulation of PCSK9 causes an increase of LDLR degradation, which results in decrease of apoB lipoprotein uptake, and a consequent increase in plasma lipoprotein concentration, including LDL. Therefore, PCSK9 has become a new target for lipid lowering therapy. The aim of this review is to consider current data on metabolic and dietary regulation of PCSK9 and its effect on cholesterol and apoB lipoproteins metabolism and risk of cardiovascular disease.
SOLAR ENERGY CONTROL AND POWER QUALITY IMPROVEMENT USING MULTILAYER FEED FORWARD NEURAL NETWORK
Authors: Dehini R.
Published: March 2018

Oil, coal and gas continue to be the most demanded
source of energy throughout the world along. In recent years, the alarming fall
in amounts of fossil fuels and increase in atmospheric carbon dioxide
composition have been seen on several occasions. These disadvantages of fossil
fuels orientate the researchers toward renewable energy sources as a more
durable long-term solution. The aim of this paper is to present a shunt active
power filter (PAPF) supplied by the Photovoltaic cells ,in such a way that the
(PAPF)  feeds the linear and nonlinear
loads by harmonics currents and the excess of the energy is injected into the
power system. In order to improve the performances of conventional (PAPF) This
paper also proposes artificial neural networks (ANN) for harmonics
identification and DC link voltage control. The simulation study results of the
new (SAPF) identification technique are found quite satisfactory by assuring
good filtering characteristics and high system stability
A NUMERICAL STUDY OF FORCED CONVECTIVE FLOW IN MICROCHANNELS HEAT SINKS WITH PERIODIC EXPANSION-CONSTRICTION CROSS SECTION
Authors: BELHADJ Abdelkadir
Published: March 2018

This paper aims to study numerically
the laminar convective heat transfer of ionized water flow inside rectangular
heat sinks with periodic expansion-constriction cross-section; each heat sink
consists of parallel microchannels system with 4 mm wide and 0.1 mm deep in
constant cross-section segment. 
Two-dimensional laminar numerical simulations, based on Navier-Stoks
equations and energy equation, are obtained under the same boundary conditions
for different microchannels. In this study, the heat transfer and pressure drop
inside microchannels with cross-section (cylindrical grooves and triangular
cavities) are compared with that of simple smooth microchannel at Reynolds
number ranging from 150-1500; an increase in pressure drop of 44% for all
microchannels  is observed with Reynolds
number increasing.  The obtained results
indicate an enhancement in Nusselt number for all microchannels at all Reynolds
number values with a maximum enhancement of 36%, these ameliorated thermal
parameters attribute to enhance the heat transfer efficiency of proposed
microchannels. Which improve the effect of periodic expansion-constriction
cross-section on the heat transfer performance for microelectromechanical
systems (MEMS) cooling phenomena.

 
Comparative study on open appendicectomy versus laparoscopic appendicectomy in a tertiary care centre
Authors: S. Naraintran , David S. Sandeep Kumar , K. Raveendran , B. K. Eashwara Pilla
Published: March 2018

Background: Appendicectomy is one of the most common procedure in general surgery, accounts for approximately 1% of all surgical operation. Laparoscopic appendicectomy are likely to have less postoperative pain, early discharge, decreased wound infection, better cosmesis and also early return to routine work. Laparoscopic procedure for appendicectomy is compared with open surgical technique with respect to duration of surgery, post operative pain, duration of analgesic, post operative complications, post operative length of hospital stay and return to routine work.Methods: This is a prospective and comparative study from September 2013 to August 2014 involved 100 cases, 50 open and 50 lap appendicectomy, which were randomly selected and were operated in department of surgery, Dr S. M. C. S. I. Medical College, Karakonam.Results: In present study pain score was 2.7±0.9 for open group as compared to 1.3±0.5 in lap group (P<0.05) because of longer incision stretch of muscles and wound infection. Post operative complications like vomiting was lower in laparoscopic group with 8% as compared with 36% in open group (P<0.05) and ileus was lower in lap group with 17.3±7.1 and for open group 30.8±8.9 with P<0.05 which were significant. There is significant reduction in incidence of post operative wound infection in lap group 4% as compared to open group 26% (P<0.05). Duration of post operative hospital stay was significantly low for lap group 2.8±0.9 as compared to open group 4±2.9. The return to normal activity was low for lap group 8±3.15 days as compared to open group 13.7±3.15 days. Duration of surgery for open appendicectomy was 48.2±12.4 and for lap appendicectomy was 68.5±20.3.Conclusions: Laparoscopic appendicectomy is better than open appendectomy in selected patients with acute or recurrent appendicitis.
Labor Migration from Third Countries to Swedish Low-wage Jobs
Authors: Frödin Olle , Kjellberg Anders
Published: March 2018

Since December 2008, Sweden has more liberal rules for labor immigration from ‘third countries’ – countries outside the European Union (EU) and European Economic Area (EEA) – than any other country in the Organisation for Economic Co-operation and Development (OECD). The introduction of employer-driven labor immigration, motivated by the need to address labor shortages, resulted in large inflows of migrants in low-skilled occupations in labor surplus sectors. This article examines the situation of the approximately 500 restaurant and cleaning workers who were granted work permits in Stockholm in 2012. More than four out of ten labor migrants ‘switched track’ from asylum seekers, students, or family connection. Every second worker was recruited to companies without collective agreements. In several cases, a nationality/ethnic link between migrant and employer appears to exist. The reasons why so many low-skilled labor migrants in nonseasonal occupations were recruited are discussed. Finally, alternative explanations for the decline of this type of labor migration after 2011 are considered.
Introduction to 2018-1
Authors: Buch Anders
Published: March 2018

What is the matter with contemporary working life? This question might indicate that something has gone astray in the way the labor market functions, or how it affects the wellbeing of working people. But the question might also be understood in a more profound sense: what really matters to people in working life? How do people (fail to) find meaning in the activities that they are involved in during work? What do people care about when working? (...)
İleri Patates Hatlarının Kuraklık Toleransının In Vitro Koşullarda Belirlenmesi
Authors: ÖZKAYNAK Ercan , ŞİMŞEK Tuğba
Published: March 2018

Araştırma bazı ileri patates hatlarında in vitro
koşullarda PEG 6000 kullanılarak oluşturulan kuraklık stresinin etkisini
belirlemek amacıyla yapılmıştır. Araştırma doku kültürü laboratuvarında 2016
yılı Ocak - Mayıs ayları arasında gerçekleştirilmiştir. Araştırma tesadüf
blokları deneme desenine göre; MS0: PEG yok, P1: %3 PEG, P2= %10 PEG ve P3=%15
PEG olarak adlandırılan 4 PEG konsantrasyonu kullanılarak 3 tekerrürlü olarak
yapılmıştır. Bitki boyu, bitki başına boğum sayısı ve bitki yaş ağırlığı gibi
bitki özellikleri 20 ve 40 günlük kültür periyotlarında ölçülmüş ve değerlendirilmiştir.
Genel olarak P1 (MS + %3 sukroz + 7 g/lagar + %3 PEG), P2 (MS + %3
sukroz + 7 g/lagar + %10 PEG) ve P3 (MS + %3 sukroz + 7 g/lagar
+ %15 PEG) ortamlarına göre tüm bitki özelliklerinde en yüksek değerler MSO (MS
+ %3 sukroz + 7 g/l agar ) ortamında elde edilmiştir. Araştırma sonuçlarına
göre PEG konsantrasyonu artıkça bitki boyu, bitki başına boğum sayısı, bitki
yaş ağırlığı ve bitki büyüme ve gelişmesi azalma göstermiştir. Araştırma
sonucuna göre 13-80-44, 22-99-33 ve 12-69-39 ileri hatları PEG 6000 içeren in
vitro koşullarda kuraklık toleransı yüksek hatlar olarak seçilmiştir.
Medea in Etruscan Art
Authors: Kobakhidze Ekaterine
Published: March 2018

It could be said with some precision, that in Antiquity the myth of the Argonauts and especially of Medea herself as a personage of this myth, has enjoyed popularity not only in Greece but also outside its territories. The first among the Italic tribes to be introduced to the personage of Medea no doubt were the Etruscans, who were the first to establish intensive contacts with the Greeks from Euboea founding a colony in Cumae, Italy. It is noteworthy that the first image of Medea in the World Art is seen on Etruscan ceramics. The paper gives detailed analyses of   Etruscan artefacts on which Medea appears, providing a solid precondition for substantive conclusions. Some new versions of an interpretation expressed in relation to each of the artefacts on the basis of critical analysis of Etruscan archeological material, of classical texts and of previously undertaken modern research, are provided. Images of Medea in Etruscan art confirmed from the Orientalist era to the Hellenization period represent an original, local interpretation of Medea's image. Medea's magical art turned out to be familiar to the Etruscans, who were well known all throughout the Mediterranean for divination and being experts of magic. In contrast to the Greeks, they turned Medea into an object of cult worship, identifying her with the Etruscan sun god Cavatha.
Óleos essenciais e eugenol como anestésico para Serrasalmus rhombeus
Authors: ALMEIDA Ana Paula Gottlieb , HEINZMANN Berta Maria , VAL Adalberto Luis , BALDISSEROTTO Bernardo
Published: March 2018

Esse estudo avaliou os perí­­odos de tempo de indução e recuperação anestésica de Serrasalmus rhombeus expostos aos óleos essenciais (OEs) de Aloysia triphylla e Lippia alba e eugenol, bem como se esses anestésicos podem ser usados no transporte dessa espécie, através da análise do comportamento natatório. Os peixes foram colocados em aquários contendo diferentes concentrações de OE de A. triphylla ou OE de L. alba ou eugenol, e posteriormente foram transferidos para aquários contendo somente água, para avaliar o tempo de recuperação. No segundo experimento, o comportamento foi analisado durante exposição aos OEs ou eugenol nas concentrações 5 ou 10 ÂµL L-1. As avaliações foram realizadas em 0, 1, 5, 10 e 15 min de exposição. Peixes expostos a 150, 200 e 50 ÂµL L-1 de OE de A. triphylla, OE de L. alba e eugenol, respectivamente, apresentaram tempo de indução anestésica menor que 3 min e tempo de recuperação menor que 10 min. Concentrações de 50 ÂµL L-1 de ambos OEs e 25 ÂµL L-1 de eugenol causaram somente sedação. Exposição a 5 e 10 ÂµL L-1 de OEs e eugenol diminuí­­ram o tempo de natação dos peixes. Ambos os OEs e o eugenol foram efetivos para anestesia e podem ser utilizados para transporte de S. rhombeus
Substituição de fonte proteica em dietas práticas para Camarão-da-Amazônia
Authors: CAGOL Luana , SANTOS Lilian Dena dos , PONTES Tânia Cristina , ZADINELO Izabel Volkweis , BALLESTER Eduardo Luís Cupertino
Published: March 2018

O objetivo deste trabalho foi avaliar o melhor ní­­vel de substituição da farinha de peixe (FP) pelo farelo de soja (FS), como fonte de proteí­­na em dietas práticas para juvenis de Macrobrachium amazonicum. Juvenis com peso médio inicial de 0,16 Â± 0,66 g foram estocados em uma densidade equivalente a 150 juvenis m-2 em sistema de recirculação. Os tratamentos consistiram das seguintes proporções de farinha de peixe e farelo de soja (FP:FS): 0:100, 20:80, 40:60, 70:30, 100:0 com cinco repetições por tratamento. Ao final de 45 dias de experimento, os camarões foram contados, medidos e pesados, bem como foi realizada análise bromatológica corporal. A sobrevivência manteve-se superior a 94% em todos os tratamentos (p>0,05). A análise bromatológica corporal apresentou diferenças significativas entre os tratamentos apenas para proteí­­na bruta (p<0,05). Os resultados da análise de desempenho zootécnico demonstraram que a inclusão de até 30% de FS em substituição a FP (70:30) não interferiu significativamente no desempenho dos camarões, possibilitando uso do farelo de soja em dietas para juvenis de camarão amazônico.
On the Learning Method, Properties of the Extended Functional-Type SIRMs Connected Fuzzy Inference Model and Their Application to a Medical Diagnosis System
Authors: Krieken Diederik van , Seki Hirosato , Inuiguchi Masahiro ,   University of Groningen  43-2 John Franklinstraat, Amsterdam 1056 SX, the Netherlands,   Graduate School of Engineering Science, Osaka University  1-3 Machikaneyama-cho, Toyonaka, Osaka 560-8531, Japan
Published: March 2018

Seki et al. have proposed the functional type single input rule modules fuzzy inference model (functional-type SIRMs model, for short) which generalized consequent part of SIRMs model to function. However, it is too strict to satisfy the equivaence conditions of T–S inference model. Therefore, this paper proposes an extended functional-type SIRMs model (EF-SIRMs, for short) in which the consequent part of the functional-type SIRMs model is extended to a function with 1 dimensional polynomial from a function with n dimensional polynomial, and its properties are clarified. Further, it shows the ability of this model becomes greatly larger than that of ordinary functional-type SIRMs model. Moreover, it proposes a learning method of the EF-SIRMs model, and it is applied to a medical diagnosis, and compared with the conventional SIRMs models.
Relationship Between Cerebral Aneurysm Development and Cerebral Artery Shape
Authors: Yasugi Marin ,   Graduate School of Engineering, University of Hyogo 2167 Shosha, Himeji, Hyogo 671-2280, Japan, Hossain Belayat , Nii Manabu , Kobashi Syoji
Published: March 2018

Lifestyle and genetics are known to be the major factors causing cerebral aneurysms, but some studies suggest that the shape of cerebral arteries might be correlated with the risk of aneurysm occurrence. This study focuses on the shape of cerebral arteries where cerebral aneurysms tend to occur. First, it extracts the shape feature of the cerebral artery ring, which is a predilection site of cerebral aneurysm, from 3-D magnetic resonance angiography images, and calculates four types of shape feature vectors – 3-D shape, bifurcation angle, degree of meandering, and direction of the branch points. Then, it estimates the risk of cerebral aneurysms occurring, based on the extracted features using support vector machine. To validate the proposed method, we conducted a leave-one-out cross validation test using 80 subjects (40 subjects with and 40 subjects without cerebral aneurysms). The method using a 3-D artery shape achieved 75% sensitivity and 75% specificity; the one using the bifurcation angle showed 47% sensitivity and 41% specificity. The method using the degree of meandering showed 55% sensitivity and 53% specificity, and the one that used the direction of the six branch points showed 30% sensitivity and 27% specificity. These results show that the 3-D artery shape could be a possible indicator for predicting the risk of developing cerebral aneurysms.
Multi-Objective Solar Farm Design Based on Parabolic Collectors
Authors: Alfughi Zakiya ,   Department of Electrical, Computer, and Software Engineering, University of Ontario Institute of Technology (UOIT) 2000 Simcoe Street, North Oshawa, Ontario L1H 7K4, Canada, Rahnamayan Shahryar , Yilbas Bekir
Published: March 2018

The configuration of solar farms, in which solar collectors are arranged in rows, is related to field and collector characteristics and solar radiation data. The main parameters considered during the optimization of solar farm designs include the number of collector rows, the center-to-center distance between collectors, collector inclination angles, and the rim angles. Solar collectors can be subjected to shading depending on the spacing between the collector rows, collector height and angle, row length, and latitude of the solar field. This study aims to optimize solar farm design by ensuring the farm receives the maximum incident solar energy and incurs the minimum deployment cost. The proposed mathematical model for photovoltaic panels is presented in detail. A multi-objective evolutionary algorithm, a non-dominated sorting genetic algorithm-II (NSGA-II), is used to achieve an optimum solar farm design that incorporates parabolic trough panels. The performances of the parabolic and flat panels are also compared, and the findings are discussed in detail. Based on the obtained results, we can verify that the parabolic PV model could generate more energy than the flat model. However, at the same cost, the flat PV model generated more energy than the parabolic model. There is a trade-off between the absolute values of the various objectives, and a solution can be selected based on the customer’s requirements and desires.
Tendency of English Teaching Based on Content-Based Instruction in China
Authors: Li Yafang
Published: March 2018

The purpose of this study is to serve as guidance to academics that are starting or currently developing their research within the field of content-based instruction in China. This paper presents a bibliometric analysis on content-based instruction, making use of the National Knowledge Infrastructure database to perform it. The identified articles were analyzed concerning year of publication, citations, topics keywords and authors. This analysis comprises fundamental issues such as (i) the number of studies published per year, (ii) the most cited studies on content-based instruction between 2010 and 2018, (iii) the most frequent words used in the title of Content-based instruction studies in China, and (iv) assessment of studies citing content-based instruction. Results reveal a growth in the number of publications on content-based instruction for the 2010–2014 period. Although, since 2014 this growth has decelerated, the number of publications on this topic remains noteworthy. This study brings tendency of CBI in China for those academics and practitioners attempting to analyze and deepen within this particular field of research. At the same time it provides some insights concerning the future development and progress of content-based instruction in the English teaching.
Impact of Medicaid Expansion on Access to Opioid Analgesic Medications and Medication-Assisted Treatment
Authors: Sharp Alana , Jones Austin , Sherwood Jennifer , Kutsa Oksana , Honermann Brian , Millett Gregorio
Published: March 2018

Objectives. To assess the impact of the expansion of Medicaid eligibility in the United States on the opioid epidemic, as measured through increased access to opioid analgesic medications and medication-assisted treatment.

Methods. Using Medicaid enrollment and reimbursement data from 2011 to 2016 in all states, we evaluated prescribing patterns of opioids and the 3 Food and Drug Administration–approved medications used in treating opioid use disorders by using 2 statistical models. We used difference-in-differences and interrupted time series models to measure prescribing rates before and after state expansions.

Results. Although opioid prescribing per Medicaid enrollee increased overall, we observed no statistical difference between expansion and nonexpansion states. By contrast, per-enrollee rates of buprenorphine and naltrexone prescribing increased more than 200% after states expanded eligibility, while increasing by less than 50% in states that did not expand. Methadone prescribing decreased in all states in this period, with larger decreases in expansion states.

Conclusions. The Medicaid expansion enrolled a population no more likely to be prescribed opioids than the base Medicaid population while significantly increasing uptake of 2 drugs used in medication-assisted treatment.
Increasing Industry Support Is Associated with Higher Research Productivity in Orthopaedic Surgery
Authors: Boddapati Venkat , Sachdev Ridhi , Fu Michael C. , Camp Christopher L. , Marx Robert G. , Dines Joshua S.
Published: March 2018

Background:

Orthopaedic surgeons receive a disproportionately small share of funding from the National Institutes of Health, but they receive the largest amount of funding from industry sources. The purpose of this study was to examine the association between payments from industry partners and research productivity among orthopaedic research authors, as well as to identify predictors of high research productivity.

Methods:

United States-based physicians who published an article in 2016 in The Journal of Bone & Joint Surgery or The American Journal of Sports Medicine were included in this study. These authors were queried in the Centers for Medicare & Medicaid Services Open Payments database (OPD) to determine the amount of industry payments received, and on Scopus, a bibliometric web site, to assess the quantity (total publication count) and quality (Hirsch index [h-index]) of each author’s research. Nonparametric testing was used to compare the h-index and the total publication count of authors by payments received and academic position. Multivariate regression was used to identify independent predictors of high research productivity.

Results:

Of the 766 included authors, 494 (64.5%) received <$10,000 per year, 162 (21.1%) received between $10,000 and $100,000, and 110 (14.4%) received >$100,000 in total payments. The h-index increased significantly from a mean (and standard deviation) of 13.1 ± 12.9 to 20.9 ± 14.4, and to 32.3 ± 16.7, from the lowest to highest payment cohorts, as did total publication count. When authors were stratified by academic position (assistant professor, associate professor, full professor, and nonacademic), those who received more industry payments (>$100,000) had a higher h-index and total publication count at all academic levels relative to lower-earning (<$10,000) authors. Independent predictors of a high h-index included industry payments of between $10,000 and $100,000 (odds ratio [OR], 1.63; p = 0.048), payments of >$100,000 (OR, 5.87), associate professorship (OR, 6.53), full professorship (OR, 33.38), and last authorship (OR, 2.22) (p < 0.001 for all comparisons unless otherwise noted).

Conclusions:

Although this study does not establish a causal relationship, we identified increasing industry payments as an independent predictor of research productivity among authors at all academic levels who had published peer-reviewed orthopaedic research.
Morfologi Bunga dan Korelasinya terhadap Kemampuan Menyerbuk Silang Galur Mandul Jantan Padi
Authors: Rumanti Indrastuti A. , Purwoko B. S. , Dewi Iswari S. , Aswidinnoor Hajrial , Satoto Satoto
Published: March 2018

Good male sterile lines should have high and stable sterility, as well as have good characters of flowers that enhances the outcrossing ability. Research was conducted at Sukamandi field station during DS of 2010 to study the character and flowering behaviour and their genetic variability among the new CMS lines. Five new CMS lines were tested in the field in three replicates of randomized complete block design. The results showed that CMS derived from the Wild Abortive, Kalinga and Gambiaca all were early flowering. The new CMS lines have better flower characters than that of IR58025A, including the following: bigger stigma, higher stigma exsertion percentage, wider degree of glume opening, and longer duration of glume opening. Better flowering behaviour enhanced the ability of outcrossing, and resulted in seed set obtained from CMS lines, up to 25.90%; the traditional IR58025A CMS line produced seed set of only 2.98%. The significant positive correlation was found between seed set with stigma width (r = 0.44*), with stigma exsertion (r = 0.54*); and with degree of glume opening of male sterile lines (r = 0.42*); also with filament length (r = 0.47*) and degree of glume opening of maintainer line (r = 0.57**). Those characters are important for the seed set of CMS lines in the hybrid seed production.