bluuebunny/crossref_metadata_2025 huggingface dataset:
Development Of An Elisa Method For The Measurement Of Cd44 Expression In Human Serum
Authors:   ,   Cork Institute of Technology, Hurley Ciara
Published: June 2024

CD44 is a cell surface glycoprotein (mol. wt. =85-95 kDa) which has been implicated in lymphocyte-HEV interactions and the process of lymphocyte homing. CD44 is a complex glycoprotein which undergoes extensive alternative splicing to generate various CD44 isoforms. CD44 functions include the delivery of an activation signal to T-cells, binding to hyaluronate, mediation of lymphocyte homing, and the spread of metastatic cells. CD44 has been particularly implicated in the dissemination of non- Hodgkin's lymphoma and as such may serve as a useful prognostic marker of disease progression. CD44 measurement in serum may provide a rapid, inexpensive and relatively non-invasive prognostic marker for NHL. Commercial ELISA systems have been developed for such a purpose and were assessed as part of this study. Two assays were evaluated but both were found to be unsatisfactory. The lack of efficacy of the assays led to the development of an 'in-house' ELISA system. The development of such a system requires CD44 antigen, which despite several approaches to the various manufacturers, proved impossible to obtain. Cloned CD44 cDNA was therefore used to generate antigen by recombinant DNA methods. CD44 cDNA was subcloned into the pTrcHis2 expression vector . CD44 protein expression was induced by IPTG and purified by affinity chromatography. The presence of the protein was confirmed by SDS-PAGE and western blot analysis. The protein was quantified using a Hitachi 911 analyser.
The Electrodynamic Levitation Of A Collar : Analysis, Experimentation And Simulation
Authors:   ,   Cork Institute of Technology, Nixon Philip
Published: June 2024

"This dissertation describes various methods of maintaining a collar levitated in a vertical axis, using the well-known principle of electromagnetic induction between two circuits. The advantages of closing the magnetic loop around the collar, to obtain large radial flux cutting the collar and, therefore, large lifting forces for a given induced current, are considered in depth. The ideal magnetic circuit and the equivalent electrical circuit are used in developing a model for two topologies of core (both an open and closed-circuit core) levitating a nonmagnetic conducting collar above a coil. Various affects that degrade the performance of the levitation rig from the ideal, are discussed, and then incorporated into the model. Particular emphasis is placed on the levitation of a collar, highlighting the differences that occur when levitating a collar, as opposed to levitating a ring. In particular the distribution of the flux over the height of the collar is considered, as an accurate description of this distribution leads directly to a good model for the levitation system. The mutual inductance of mutually coupled coils and the coupling coefficient between these coils is also considered at length. This is necessary, as it is the accurate definition of the mutual inductance that defines the accuracy of the model. Care is taken to maintain the theory as general as possible. In this way the resulting model is not tied to any particular topology and it is a relatively simple task to apply the model to any application. Emphasis is placed on the practicality of the model. Therefore, many experiments have been carried out, and the results from these are compared with those obtained from the model. Also, throughout the development of the model, demonstrative experiments are carried out to show the validity of some of the more crucial parts of the theory. The theory results are also compared with the results obtained from a electrodynamics simulation package. In all of the results obtained, a good agreement is found across a range of levitated distances, different frequencies of operation, various weights of the levitated member and various types of materials. The dissertation closes by considering some applications of the electrodynamics levitation system, in particular, its application to Load Cells and Magnetic Bearings."
Molecular Analysis Of The Factor V-leiden Mutation In A Cardiac Transplant Patient Population
Authors:   ,   Cork Institute of Technology, Maher Caroline
Published: June 2024

"Venous thrombosis is a serious health problem affecting 1 in 1000 individuals annually. Until recently the pathogenic factors underlying thrombosis were associated with genetic defects in protein C, protein S and antithrombin III. However these were recognised in fewer than 5-10% of thrombotic patients. A breakthrough was made with the discovery of activated protein C resistance (APCr) which is associated in 90% of cases v/herein a G-->A transition in the factor V gene results in an abnormal molecule, Factor V Leiden. APCr is a major risk factor for thrombosis being present in 20-60% of thrombotic patients. Recently a G-^A new mutation at the 3’-untranslated region (UTR) of the prothrombin gene was described. This mutation increases the level of prothrombin in blood by a mechanism(s) which remain(s) to be defined. Furthermore this mutation is thought to be linked to thrombosis since it is present in 6% of thrombotic cases. This work is divided between three areas. The first part of this study examined 40 thrombotic patients and 40 normal individuals using two commonly used coagulation-based assays for detection of APCr. Comparisons of analytical specificity and sensitivity were made as a means of critically assessing the kits performance. Genotype assignments for factor V were also determined using site- directed mutagenesis (SDM)-polymerase chain reaction (PCR). In the second part of this study a ‘single-tube’ amplification refractory mutation (ARMS) detection strategy for factor V Leiden and the prothrombin variant was developed. Essentially these strategies used fluorescent-based differentially- labelled primers to simultaneously amplify both allelic-types. The final stage of this work examined the genotypes and ‘rest-time’ clotting properties of 75 thrombotic patients who presented for cardiac venografting. Initially the viso-elastic properties of each subjects blood was studied using thromboelastography (TEG). Subsequently genotyping was performed using SDM-PCR protocols to detect factor V Leiden, the prothrombin variant and other mutations in the blood clotting pathway components of protein C and antithrombin III. Comparisons between TEG and genotype data were made. Results of this analysis has significant health economic implications."
Development And Validation Of Flow-injection (continuous-flow) Elisa Techniques.
Authors:   ,   Institute of Technology Tralee, Spillane Declan
Published: June 2024

A flow-through enzyme-linked immunosorbent assay was developed based on affinity chromatography using the determination of ferritin in serum as a model system. In this method, samples and standards are introduced to separate columns containing immobilised anti-ferritin antibody, and antigen bound by solid-phase antibody is subsequently detected using an anti-ferritin-alkaline phosphatase conjugate. To detect immobilised label, p-nitrophenyl phosphate is added and product is developed in the column at room temperature. Following elution of product from the column, the absorbance is measured and the columns are regenerated using a low pH elution. The final developed system requires approximately 1.5 h for the simultaneous assay of standards and up to forty samples. The lower limit of detection using a 200 μl assay volume is 1.82 x 10-15 mol or 9.11 x 10-12 mol/l (4.1 μg/l). However, there is potential to increase the assay sensitivity further through the use of amplification systems for alkaline phosphatase label. In addition, the present assay gives accurate results, good precision, and is easy to perform. The immunoaffinity columns have been shown to be stable for at least ten assays and presumably could be used for an even greater number. By using different immobilised and labelled antibodies, this method could easily he adapted for use with other analytes.
Methicillin Resistant Staphylococcus Aureus (mrsa): Molecular Detection And Dna Fingerprinting
Authors:   ,   Cork Institute of Technology, Cotter Leslie
Published: June 2024

"Throughout the 1990s, the incidence of methicillin-resistant Staphylococcus aureus has increased in many health care areas including acute and chronic care facilities, outpatient clinics and in the community. Once introduced into a health care environment, this nosocomial pathogen can spread rapidly and as MRSA are resistant to multiple antibiotics, treatment is often difficult. Therefore effective infection control measures are required to prevent cross-infection and further spread of endemic strains. In this study, a sensitive and specific triplex-PCR assay was designed for MRSA detection, wherein three genes, the methicillin resistance gene (mecA). femA and the extracellular thermonuclease gene (rmc) were simultaneously amplified. The products of this triplex-PCR were analysed using a number of detection formats (including conventional agarose gel electrophoresis, “dot blot” analysis, colour amplified PCR detection system (CAPS) and fluorescent GeneScan technology). Such PCR detection assays do not investigate the complex epidemiology of this pathogen. Rapid and accurate epidemiological typing methods are required to identify the source and track the spread of different MRSA clinical isolates. To this end, the genetic relationship(s) among two Cork University Hospital (CUH) MRSA outbreaks was successfully analysed using rep-PCR with a single RW3A primer, together with agarose gel electrophoresis and fluorescent GeneScan analysis. The fluorescent triplex-PCR and RW3A fingerprinting strategies were multiplexed and this permitted the development of a combined detection and typing scheme termed COGEDET for MRSA strains. In addition, a number of conserved RW3A-generated amplicons were characterised by cloning and sequencing to determine their genomic origins."
Conjugated Bilirubin Measurement Re-examined: A New 'approach'.
Authors:   ,   Cork Institute of Technology, Kelleher Aidan
Published: June 2024

Conjugated bilirubin is an important but difficult metabolite to measure accurately, elevated levels of conjugated bilirubin in the serum are indicative of obstructive jaundice and therefore can be used to discriminate this disorder from other forms of unconjugated hyper bilirubinaemia.
REVISIÓN DEL USO DE ANALGÉSICOS EN EL MANEJO DEL DOLOR AGUDO Y CRÓNICO. DESAFÍOS, EVIDENCIAS Y PERSPECTIVAS
Authors: María Carmen Albiac Cubeles , Laura Piedrafita Rodríguez , Ana Zamorano Sotomayor , Raquel García Castellanos , Beatriz Grao Fernández
Published: June 2024

INTRODUCCIÓN: El manejo del dolor según la escala analgésica de la OMS, asume un enfoque escalonado para el manejo del dolor, iniciando con fármacos no opioides como paracetamol y antiinflamatorios no esteroideos (AINEs) para el dolor leve, pasando a opioides débiles para dolor de intensidad moderada y finalmente a opioides potentes para el dolor intenso. Se buscará destacar la importancia de la individualización del tratamiento del dolor, la selección apropiada del analgésico y la dosificación adecuada conforme a la escala analgésica y también la integración de asociaciones entre analgésicos y con otros fármacos que mejor funcionan en conjunto para aliviar el dolor intenso. OBJETIVOS: Este artículo tiene como objetivo general explorar y aclarar el uso correcto de analgésicos siguiendo la escala de analgesia de la OMS y las asociaciones entre analgésicos y otros fármacos para el tratamiento del dolor intenso agudo y crónico. Uno de los objetivos específicos es brindar una orientación clara sobre el uso de la escala analgésica propuesta por la OMS, describiendo cómo puede adaptarse a distintas situaciones clínicas para el manejo del dolor. METODOLOGÍA: Se ha realizado una búsqueda en múltiples bases de datos como MEDLINE (PubMed), EMBASE, Web of Science, Enfispo, Biblioteca Cochrane y Google Académico, utilizando una combinación de términos MeSH y palabras clave relacionadas con “Manejo del dolor, Analgésicos opioides, Antiinflamatorios no Esteroideos, dolor agudo y dolor crónico” y se eligieron artículos a texto completo. RESULTADOS: La investigación compilada y analizada en este artículo ofrece una comprensión exhaustiva de los principios que deben guiar el uso de analgésicos según la escala analgésica de la OMS, así como de las asociaciones eficientes con otros fármacos para el tratamiento del dolor agudo y crónico.
FACTORS AFFECTING SUCCESSFUL AND PROLONGED LACTATION: CURRENT EXPERIENCE AND POSSIBLE PROSPECTS
Authors:   Surgut State University, Surgut, Russia, Добрынина О. Д. , Тепляков А. А. ,   Surgut State University, Surgut, Russia
Published: June 2024

The problem of breastfeeding and an increase in its prevalence are examined at three possible levels of influence on the mechanisms for implementing breastfeeding: state, health care system, and personal. The study reviewed the literature on managing issues of implementation and prevalence of breastfeeding programs, the lactation period, approaches to forming lactation dominants, lactation challenges, and the need for prelactation preparation for pregnant women in order to increase breastfeeding adherence. The study also examined the issues that prevent breastfeeding from overcoming its low barrier.
RECONSTRUCTIVE SURGERY OF LONG-TERM AFTEREFFECTS OF LOWER LIMBS BURNS
Authors:   Republican Scientific Center of Cardiovascular Surgery, Dushanbe, Republic of Tajikistan, Ходжамурадов Г. М. , Шаймонов А. Х. ,   Republican Scientific Center of Cardiovascular Surgery, Dushanbe, Republic of Tajikistan, Исмоилов М. М. ,   Republican Scientific Center of Cardiovascular Surgery, Dushanbe, Republic of Tajikistan, Саидов М. С. ,   Republican Scientific Center of Cardiovascular Surgery, Dushanbe, Republic of Tajikistan
Published: June 2024

The study aims to comparatively assess long-term results of surgical treatment of burns aftereffects using local tissues and free flaps from 2005 to 2022. The surgical treatment was performed on 84 patients with aftereffects of lower limbs burns. The mean age of the patients was 9.2 ± 1.7 years. The patients were divided into two clinical groups: group I included 51 patients (60.7 %) with local tissue grafting, group II included 33 patients (39.3 %) with the author’s method of free flap grafting using tissue from the groin area, which allowed for reducing the occurrence of relapses to a minimum. Two patients who repeatedly underwent unsuccessful surgeries required an additional surgical intervention. Moreover, it can be considered successful, given that prior to the surgical intervention, there were practically no movements in the joints. Thue, the available data show the effectiveness of plastics with a free flap of defects remaining during excision of postburn tightening scars in the lower limbs. However, in individuals under 18 years of age, future bone growth should be taken into account, as well as the proximity of the lesion to the joints, in order to avoid tension and the need for reoperations.
OBSTETRIC HEMOLYTIC UREMIC SYNDROME ASSOCIATED WITH PREGNANCY IN A PATIENT WITH INFECTION AND MASSIVE BLEEDING: A CLINICAL CASE
Authors:   Khanty-Mansiysk State Medical Academy, Khanty-Mansiysk, Russia, Васильковская Е. Н. ,   District Clinical Hospital, Khanty-Mansiysk, Russia, Кутефа Е. И. ,   District Clinical Hospital, Khanty-Mansiysk, Russia, Каспарова А. Э. ,   Khanty-Mansiysk State Medical Academy, Khanty-Mansiysk, Russia,   District Clinical Hospital, Khanty-Mansiysk, Russia, Никитин Д. Ю. ,   District Clinical Hospital, Khanty-Mansiysk, Russia, Шептухина Д. Е. ,   Khanty-Mansiysk State Medical Academy, Khanty-Mansiysk, Russia, Номанова Р. К. ,   Khanty-Mansiysk State Medical Academy, Khanty-Mansiysk, Russia, Пьянкина О. В. ,   Khanty-Mansiysk State Medical Academy, Khanty-Mansiysk, Russia,   District Clinical Hospital, Khanty-Mansiysk, Russia, Гилева С. Л. ,   Khanty-Mansiysk State Medical Academy, Khanty-Mansiysk, Russia,   District Clinical Hospital, Khanty-Mansiysk, Russia
Published: June 2024

The study aims to present a clinical case of a rare pathology such as obstetric hemolytic uremic syndrome associated with infection during pregnancy, and complicated by massive bleeding, a critical obstetric condition, and a high risk of maternal mortality in a near-miss case. The study analyzes changes in causes of maternal mortality rate in the Russian Federation, including changes towards extragenital diseases; indirect causes and embolisms; preeclampsia, obstetric bleeding, and sepsis despite their decrease in the causes of maternal mortality rate; and such diseases as thrombotic microangiopathy, which is considered a probable life-threatening maternal condition and named a critical obstetric condition, that can be diagnosed in a highinformation laboratory with an instrumental basis. Thrombotic microangiopathy is attributed to many diseases, therefore, there are many unclear and controversial issues in diagnosing such a disease during pregnancy. Its clinical symptoms include hemolytic microangiopathic anemia, thrombocytopenia, thrombosis of the terminal arterioles and capillaries of the microvascular bed, and multiple organ dysfunction.
COGNITIVE AND NEUROLOGICAL STATE OF RATS FOLLOWING THE SIMULATION OF ACUTE TRAUMATIC BRAIN INJURY ASSOCIATED WITH VARIOUS XENON CONCENTRATIONS
Authors:   Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia, Беда Е. Е. , Гребенчиков О. А. ,   Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia, Долгих В. Т. ,   Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia, Антонова В. В. ,   Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
Published: June 2024

The study aims to evaluate the efficacy of xenon inhalation at various concentrations on neurological and cognitive impairments when simulating open traumatic brain injury (TBI) in rats. Tests were performed on 35 male Wistar rats weighing from 250 to 350 g. After simulating an open traumatic brain injury, the animals received inhalation with a mixture of gases: 5 sham operated animals received only anesthesia without traumatic brain injury and inhalations, a control group with traumatic brain injury + inhalation N2 70 % / O2 30 % (group “TBI”, n = 10); an experimental group with traumatic brain injury + inhalation of xenon-oxygen 70 % / O2 30 % (group “TBI + iXe70”, n = 10), an experimental group with traumatic brain injury + inhalation of xenon-oxygen and nitrogen – Xe 35 % / O2 30 %, nitrogen 35 % (group “TBI + iXe + N2”, n = 10) for 60 minutes. After gas inhalation, the animals were observed for 14 days. On the 3rd, 7th and 14th days, the neurological limb placement test was carried out. The preservation of cognitive functions, such as learning and spatial memory, was assessed using the Morris water maze test with control testing on the 14th day. After testing, on the 14th day of observation, euthanasia was performed, and the brain was collected for research. It was found that the selected xenon concentrations in doses of 0.25 and 0.5 MAC tatistically significantly reduced the severity of both neurological deficit and cognitive impairment in 7 and 14 days, whereas increasing the xenon concentration did not significantly enhance the neuroprotective effect.
HISTORY AND EVOLUTION OF NEUROIMAGING METHODS IN EPILEPTOLOGY
Authors:   Petrovsky B. V. Russian Scientific Center for Surgery, Moscow, Russia, Мельников А. А. , Климова Н. В. ,   Surgut State University, Surgut, Russia, Воронкова К. В. ,   Pirogov Russian National Research Medical University, Moscow, Russia
Published: June 2024

The article examines history of fundamental discoveries, methods and clinical achievements in neuroimaging, their contribution to the development of diagnosing, treatment and understanding of epilepsy etiology, also as part of International League Against Epilepsy’s research. In the early stages of its development, neuroimaging had advanced rapidly in the areas of cancer detection, pneumoencephalography, pneumomiography, ventriculography, linear tomography and selective angiography. The development of epileptology was greatly influenced by the use of computed tomography and magnetic resonance imaging, which made it possible to identify pathological lesions in a large number of patients with cryptogenic epilepsy, expand the indications for surgical treatment and improve understanding of the pathogenesis of pathological processes in the brain associated with seizure activity. In recent years, functional magnetic resonance imaging, magnetic resonance spectroscopy, positron emission tomography and single-photon emission computed tomography have become the focus of attention of researchers, which revealed a huge number of different structural changes of the brain tissue, which lie at the basis of the formation of the epileptic focus and lead to the development of focal epilepsy.
PANCREATIC DUCT STENTING IN PATIENTS WITH PANCREATIC NECROSIS
Authors:   Nefteyugansk District Clinical Hospital named after V. I. Yatskiv, Nefteyugansk, Russia, Логинов Е. В. , Дарвин В. В. ,   Surgut State University, Surgut, Russia
Published: June 2024

The article reviews Russian and foreign literature on the treatment of patients with acute pancreatitis according to the relevance, as well as increase in disease frequency, high mortality rate, and persistent disability of patients with severe pancreatitis. Pancreatic duct stenting is one of the most promising treatments for pancreatic necrosis, and it can help improve the treatment of such patients with a severe disease.
ASSESSING A LIPID PROFILE IN PATIENTS WITH ALCOHOL LIVER DISEASE AFTER STANDARD TREATMENT
Authors:   Khanty-Mansiysk State Medical Academy, Khanty-Mansiysk, Russia, Коркин А. Л. , Сайтаджиев Б. Р. ,   District Clinical Hospital, Khanty-Mansiysk, Russia
Published: June 2024

The success of standard therapy for alcoholic liver disease in terms of forecasting the risks of an adverse outcome is now assessed using the degree of decrease in the activity of laboratory markers of cytolysis and cholestasis. The study aims to examine a lipid profile through comparing of laboratory parameters in 28 patients aged forty to sixty with alcoholic liver disease before and after standard treatment in terms of mortality risks. When compared to the mortal risks before and after standard treatment in the group of patients with an achieved total cholesterol level of more than 5 mmol/L, the mortality risk was significantly reduced in patients with an achieved total cholesterol level of less than 5 mmol/L. It has been demonstrated that, in the presence of significant fluctuations in cholestasis indicators, a total cholesterol level in the blood serum of less than 5 mmol/L can be used as a criterion for reducing the mortality risk in patients after standard therapy for alcoholic liver disease.
REDUCTION MAMMOPLASTY AND OBESITY: IS THERE AN INTERCHANGEABLE INFLUENCE
Authors:   Republican Scientific Center of Cardiovascular Surgery, Dushanbe, Republic of Tajikistan, Саидов М. С.
Published: June 2024

According to the studies, there is a high probability of gigantomastia development in juvenile with obesity, and mammary gland reduction may help decrease weight in such patients due to the improvement of hormones level in the organism. The article presents the results of a comparative analysis of reduction mammoplasty in patients with and without obesity. The study aims to examine the influence of obesity on short- and long-term results of performing a standard surgery with an author’s modification of reduction mammoplasty from 2010 to 2023 in 32 female patients with gigantomastia. The patients from 19 to 62 y. o. (34.5 ± 1.8) were divided into two groups: 23 women with obesity and 9 without. Performing reduction mammoplasty contributed to weight loss in the long-term postoperative period, while the recovery process itself after surgery in patients with obesity was much more difficult than in those without it. Obesity is an aggravating factor when performing reduction mammoplasty. The presence of excess body weight not only increases the severity of pain and blood loss, but can have a negative impact on the aesthetic result of surgery.
La comprensión lectora en educación secundaria
Authors: González Valenzuela María José , Barba Quintero María José , González Alicia
Published: June 2024

Uno de los objetivos educativos principales en la educación obligatoria es contribuir a desarrollar las habilidades básicas de leer y escribir. Sin embargo, en los últimos años se ha apreciado, en la Educación Secundaria Obligatoria, un bajo rendimiento académico motivado, en gran medida, por las dificultades que los alumnos presentan en comprensión lectora. La mayoría de los alumnos no poseen los mecanismos necesarios para abordar las tareas que se le proponen, que están relacionadas con el lenguaje escrito. Uno de los contribuyentes a esta situación es el contexto educativo, ya que en la enseñanza de la comprensión lectora no se dan demasiadas pautas ni estrategias concretas que sustenten su desarrollo, aprendiéndose estas destrezas de forma asistemática. Por estos motivos, en este documento se incide, en primer lugar, en entender que es la comprensión lectora, es decir, en el análisis sobre lo que hacemos cuando comprendemos un texto y lo que los sujetos no hacen para presentar dificultades en este ámbito. En segundo lugar, se pretende conocer algunas pautas de intervención psicoeducativa, como medida de mejora de la comprensión lectora, que se encuentran en la literatura. Y finalmente, se ofrece una experiencia y propuesta de trabajo para mejorar y adquirir la comprensión lectora a través del currículo escolar en esta etapa educativa.
Small-group online actors-as-instructors psychiatric clinical interview skill training: a single blind, randomised controlled study
Authors: Tsui Alice Ling , Chau Steven Wai Ho
Published: June 2024

Background:Leveraging the similarities between theatre training and psychiatric clinical interviews, our previous pilot study proved that incorporating actors as standardized patient-instructors (SPI) in communication skills training in the psychiatry module of the medical curriculum was feasible and welcomed by medical students and senior psychiatrists.Objectives:To evaluate the objective effectiveness of an online small group psychiatric clinical interview skill training program using the SPI approach in enhancing students’ clinical communication skills.Method:This is a single-blinded randomized controlled trial with two parallel arms: a control group receiving standard teaching, and an intervention group receiving a one-off intensive clinical skill training workshop instructed by trained actors, served as both simulated patients and tutors via an online platform. Students’ interview skill sub-score in the end-of-module Objective Structured Clinical Exam (OSCE) is the primary outcome measure. Results:112 Year 5 Medical students were recruited and randomly assigned into the intervention group (n=58) and the control group (n=54). The results show that there were no significant differences in their OSCE interview skill sub-score between the intervention group and the control group. Despite the non-significant examination results, participants expressed highly positive feedback towards the intervention training using the SPI approach: over 98% of students found the workshop positively impacted their clinical interview skills. Conclusion:The participants' positive subjective appraisal indicates that using a trained professional actor as the standardized patient-instructor in clinical interview skills training is feasible and welcomed by medical students. However, further improvements in the training design and objective measurement tools are needed to demonstrate the objective effectiveness of such an approach. Nevertheless, the SPI approach still holds considerable potential to enhance the acquisition of psychiatric interview skills education.
Dynamics of Women's Role in Urban Society: A Qualitative Approach
Authors: Amin Sulvahrul , Haniah St. , Firdaus Firdaus , Roslyn Roslyn
Published: June 2024

The dynamics of women's roles in urban society is a complex phenomenon that continues to change along with the times. Urban areas have become dynamic and diverse centers of life, creating challenges and opportunities for women in carrying out their roles. The purpose of the research is to explore the experiences, perceptions, and understandings of urban women about their roles in society. The research method used is a qualitative research method with a phenomenological approach. Data is obtained through in-depth interviews with 15 women from various backgrounds in Makassar city to understand women’s experiences directly and deeply, as well as direct observation of women's roles in the current urban society. The data collected will be analyzed thematically to find out the role of women in the current urban society. The results of this study show that the dynamics of women's roles in urban society have developed significantly along with social and economic transformation. In the midst of the development of cities, women are not only limited to their traditional roles as housewives, but are also increasingly actively involved in various sectors of life.
The Role of Principal Supervision in Improving Teacher Professionalism at SMAN 1 Batang Gansal Indragiri Hulu Regency Riau Province
Authors: Ridwan Ahmad , Yudistira  , Zillah Hikmatun , Khomisah Siti
Published: June 2024

Enhancing the professionality of educators is an essential component of guaranteeing the caliber of instruction in each and every educational establishment. The point of this research is to look at the professionalism of teachers at SMAN 1 Batang Gansal, to see how to improve the professionalism of teachers at SMAN 1 Batang Gansal, and to examine the contribution of principal supervision at SMAN 1 Batang Gansal, Indragiri Hulu Regency, Riau Province to teacher professionalism. The method that is being used is qualitative. Data is gathered from a variety of sources using techniques including classroom observations, document studies, and in-depth interviews. The research results reveal that in enhancing the professionalism of teachers at SMAN 1 Batang Gansal, various efforts can be made, such as pursuing higher education, attending training sessions, and organizing mentoring programs. Meanwhile, the principal of SMAN 1 Batang Gansal implements four supervision roles, namely coordinator, consultant, group leader, and evaluator. Additionally, the school principal also follows three stages in supervision: preparation, implementation, and reporting, as a systematic effort to enhance teachers' professionalism and consequently improve the quality of teaching.
Teachers’ Challenges in EFL Classroom Management
Authors: Hidayat Reski , Sunra La , Salija Kisman
Published: June 2024

Every teacher who teaches a foreign language must have challenges in teaching and managing the classroom. The objectives of this study are: (1) To find out the English teachers’ challenges in English classroom management at SMA Insan Cendekia Syech Yusuf. (2) To describe the strategies used by teachers to solve the challenges in English classroom management at SMA Insan Cendekia Syech Yusuf. The subjects of this study were three teachers who taught English subjects at SMA Insan Cendekia Syech Yusuf. This research used a qualitative method. The instruments that the researcher employed were documentation, interviews, and observation. The researcher applied Miles et al.'s theory—data reduction, data display, conclusion drafting, and verification—to the data analysis process. The study's findings suggest that: (1) Teachers have difficulties when instructing pupils in English, including inadequate vocabulary acquisition, insufficient exposure to the language, psychological issues, linguistic difficulties, and low proficiency. (2) Teachers used several strategies to overcome the challenges they faced, such as the Determination Strategy, Group Discussion Strategy, and Communication Strategy. It appears that there are still a lot of difficulties in controlling and instructing English in the classroom when it comes to some of these issues. Therefore, in order to create a safe and comfortable learning environment where learning proceeds without problems teachers must employ a variety of teaching strategies in addition to appropriate classroom management techniques.
Factors that Influence Impulse Buying: A Literature Review
Authors: Hanifah Nida , Susilaningsih  , Sabandi Muhammad
Published: June 2024

An individual's personality, way of thinking, social interactions, and response to situations play an important role in impulse buying behavior. This phenomenon is now common among consumers, who often initially have the goal of buying one item but are tempted to buy additional items that attract attention while at the market. This article reviews the impulse buying literature, the focus is on understanding the phenomenon and the factors that influence it in the purchasing context. The method used is Systematic Literature Reviews (SLR). ). The research results show several factors that influence consumer impulse buying behavior. Positive emotions, store atmosphere, and financial knowledge interact to influence impulse buying tendencies.
Influence of Environmental Conditions and The Students' Health
Authors: Baluyos Jaslyn Esther , Canastra Abby Clirame , Dionio Julveman , Ilusorio Honey , Jimenez Christian Carl , Baluyos Genelyn R.
Published: June 2024

Healthy students are not merely a result of good genes; they are also a product of an environment that fosters and encourages their well-being through a mutual influence of environmental conditions. This study determined the influence of environmental conditions on students' health in one of the basic education schools in Ozamiz City during the S.Y. 2023-2024. It employed a descriptive-correlational design with 249 Senior High School respondents chosen through simple random sampling. The Environmental Conditions and Students' Health Questionnaires with a five-point Likert scale were used as data gathering instruments. Mean, Standard Deviation, and the Pearson Product Moment Correlation Coefficient were used as the statistical tools to analyze the gathered data. Results revealed that the students' environmental conditions on air quality, water quality, access to green spaces, built environment, social and community support, transportation, and commute, and environmental were good, while noise pollution and temperature were fair. The students' overall health was good, including their physical, mental, and social health. The students' environmental conditions greatly influenced their health and well-being. The learning environment of students plays an important role in their health and well-being. School administrators may prioritize reducing noise pollution and regulating temperature while investing in sustainable practices, green spaces, and community support to create a healthier learning environment.
Exploring EFL Teachers’ Teaching Styles at a Junior Secondary School
Authors: Arif Nurindah Fadillah , Noni Nurdin , Korompot Chairil Anwar
Published: June 2024

The study aimed to find out the teachers’ teaching styles applied at SMP Telkom Makassar, students’ perceptions, and the teachers’ obstacles faced during teaching. This study was categorized as qualitative research, and the data was collected through observation, TSI questionnaire, and interview. There were six participants in this study, consisting of three teachers, and three students. The findings of this research showed that: (1) Teachers respectively applied various teaching styles in teaching English in the classroom and no one teacher applied only one style in teaching, they applied as a facilitator, delegator, formal authority, personal, expert, academic style, audiolingual, communicative style, and task-based learning style. The dominant teaching styles applied by the participants are facilitator and delegator styles. (2) The students’ perceptions, they feel comfortable learning English with their teachers because their teachers applied various styles to teach not only focusing on the book, but their teachers providing the material using interesting PPT, audio-video conversation, ice-breaking, and games to make their class fun. Another activity that the students enjoyed learning English like discussion with pairs or groups and the atmosphere that is built by the teachers such as interaction with other students, never judging, and yelling at students when they make a mistake. (3) The obstacle that the participants faced during teaching they were exhausted from teaching in large classes that consisted of many students with different characteristics and abilities. Sometimes, they are confused about the method or strategy, and media that are suitable for their students that can increase their ability in English.
Price Perception and Promotion on Honda Motorcycle Purchase Decision on CV. Various Motorcycles
Authors: Pelupessy Merry M. , Hanoeboen Bin Raudha Arif , Leiwakabessy Erly , Pitna Sancyes Henderina
Published: June 2024

Does Price Perception and Promotion affect Honda Motorcycle Purchase Decisions? Benefits of research For companies, this research is expected to help as well as contribute thoughts in strategies to increase sales volume. The method used in this study uses multiple linear regression analysis with the analysis tool used is SPSS version 26. This method is deliberately used to partially test and the coefficient of determination of the influence or not between variables. The number of samples from this study amounted to 106 respondents and the sample size was determined based on consideration using the hair formula (2010) The results of the study found that based on the results of analysis using the SPSS Program found that the variable X1 or Price Perception had a significant effect on the Purchase Decision of Honda Motorcycles because the sig value of 0.029 was smaller than 0.05 and t_calculate 2.212 ˃ t_table 1.984 and variable X2 or Promotion
Implementation of Talent Pool System to Realize Professionalism Performance State Civil Apparatus
Authors: Oktaviani Monica , Yuswanto Yuswanto , Deviani Eka
Published: June 2024

Purpose: Realizing good local government governance and ensuring the availability of professional civil servants require planned and measurable human resource management. Therefore, the Pagar Alam City Government issued Pagar Alam Mayor Regulation No. 24 of 2021 concerning the Policy for Implementing the Civil Servant Talent Pool System within the Pagar Alam City Government. To realize good local governance and ensure the availability of professional civil servants.
Method: Normative and empirical methods were employed. Data collection was carried out using field and literature studies. The data analysis was qualitatively descriptive.
Result: Implementation of the Talent pool System as a strategy of the Pagar Alam city government to realize the professionalism of the performance of the state civil apparatus, the Pagaralam city government participated in a series of events held at the Regional VII Agency of the State Civil Service Agency (BKN) Palembang by sending 9 (nine) participants. However, the mayor’s regulation has not been fully and maximally realized within the Pagar Alam City government.
Limitations: The factors that hinder the implementation of the talent pool system within the scope of the Pagar Alam city government are a lack of human resource participation and budget factors that have not been fully explained.
Contribution: Implementation of the Talent pool system as a strategy of the Pagar Alam city government to realize professionalism in the performance of the state civil apparatus.
Pengaruh Hedonic Shopping Motives, Sales Promotion, Fashion Involvement terhadap Impulse Buying Shopee
Authors: Ngadiman Sabrina , Pradana Bayu Laksma
Published: June 2024

Purpose: Consumer impulse buying has received considerable attention in consumer research. This phenomenon is interesting because it is not only driven by various internal psychological factors but also influenced by external stimuli related to the market. This study aims to determine whether there is an influence between Hedonic Shopping Motives, Sales Promotion, and Fashion Involvement on Impulse Buying of a Pradita University student class of 2020 – 2023 Business Management Study Program, Retail Management, and Accounting, who use Shopee e-commerce.
Method: A quantitative survey method was used. The sampling technique used the nonprobability sampling method and purposive sampling, with a total sample of 140 people. Data collection techniques using online questionnaires. Primary and secondary data were used in this study. The analytical tool used in this study was multiple regression using SPSS 26.
Results: The results of this research show that Sales Promotion and Fashion Involvement have no effect on impulse buying on the Shopee application, while Hedonic Shopping Motives have a significant positive effect on Impulse Buying among the Pradita University student class 2020 – 2023 Business Management, Retail Management, and Accounting Study Programs that use Shopee e-commerce.
Limitation: The limited scope of research focuses only on Pradita University students from 2020 to 2023.
Contribution: Fashion involvement has no influence on impulse buying among Pradita University students’ class 2020 – 2023 Business Management, Retail Management, and Accounting Study Programs that use the Shopee application.
Studi Empiris Terkait Loyalitas Pelanggan pada Bisnis Coffee Shop
Authors: Wijaya Vanessa , Widjaja William
Published: June 2024

Purpose: The rapid growth of coffee outlets in Indonesia has increased competition in this industry, thus encouraging each coffee outlet to continue to innovate with superior products that differentiate it from competitors. This research aims to analyze the influence of brand equity on customer loyalty at Kopi Nako outlets, by considering the role of purchasing intention variables and purchasing decisions as intervening variables.
Research Methodology: The research method used is ex-post facto with a quantitative approach. The sampling technique used is non-probability sampling with a purposive sampling method based on the population. Data was collected through questionnaires given to 104 respondents, who were consumers of Kopi Nako or had interacted directly with the Kopi Nako brand.
Results: The findings of this research reveal that there is a positive and significant influence between brand equity on customer loyalty through purchase intentions and purchase decisions.
Limitation: 1. The number of respondents is only limited to 104 respondents, researchers believe that involving a larger number of respondents can increase the level of accuracy and representation of research results. 2. The research variables that are the focus of this research are limited to brand equity, purchase intention, purchase decision, and customer loyalty. There are various other factors that might influence customer loyalty in the context of Kopi Nako, such as customer satisfaction, word-of-mouth (WOM), and marketing mix.
Contribution: The achievements of this research can contribute to the understanding of marketing theory, especially in the context of the relationship between brand equity, purchase intention, purchase decisions, and customer loyalty. Apart from that, marketing practitioners, especially those in the coffee industry such as Kopi Nako, can use these findings to develop more effective marketing strategies.
Intrusion Detection System to Secure a Network using ACNN Model and Machine Learning
Authors:   Research Scholar, Department of Computer Science & Engineering, University of Technology, Jaipur (R.J), India., Dungarani Ruchika , Gujjar Dr. Satish Narayan ,   Professor, Department of Computer Science & Engineering, University of Technology, Jaipur (R.J), India.
Published: June 2024

As cyber threats continue to evolve in sophistication and diversity, the need for robust Intrusion Detection Systems (IDS) becomes paramount to safeguarding network integrity. This research explores the application of an innovative approach by integrating an Attention-based Convolutional Neural Network (ACNN) model with machine learning techniques to enhance the accuracy and efficiency of intrusion detection. The proposed system leverages the ACNN's ability to capture contextual dependencies in network traffic data, enabling the extraction of intricate patterns indicative of potential intrusions. The ACNN's attention mechanism focuses on relevant features within the data, improving the model's discriminative power and adaptability to dynamic cyber threats. To achieve optimal performance, the ACNN is complemented with a machine learning framework that includes feature engineering, dimensionality reduction, and classification algorithms. This integrated approach allows the system to adapt and learn from evolving attack vectors, providing a proactive defense mechanism against both known and unknown threats. The research evaluates the proposed ACNN-based IDS using benchmark datasets and real-world network traffic scenarios. Comparative analysis against traditional IDS models showcases the superiority of the ACNN in terms of detection accuracy, false positive rates, and computational efficiency. Furthermore, the system's adaptability to emerging threats is demonstrated through continuous learning and retraining mechanisms. Results indicate that the ACNN-based IDS not only exhibits superior performance but also demonstrates resilience against evasion techniques employed by malicious actors. The research findings contribute to the advancement of network security by presenting a cuttingedge solution that combines deep learning and machine learning for effective and adaptive intrusion detection.
La deplastificazione è auspicabile
Authors: Lombardi Vallauri Edoardo
Published: June 2024

Una lettrice lamenta l’assenza del termine deplastificazione dai dizionari, e si domanda se sia lecito usarlo, ad esempio per esprimere il proprio desiderio di eliminare la plastica che affligge gli oceani (e in verità molti altri luoghi).
Pengenalan Kebudayaan Bengkulu melalui Rancang Bangun SIPEDALU
Authors: Renaningtias Nurul , Sari Julia Purnama
Published: June 2024

Kehadiran teknologi berperan penting dalam semua sektor kehidupan, salah satunya sektor kebudayaan dan pariwisata. Sektor kebudayaan dan pariwisata merupakan sektor yang sangat potensial dalam pembangunan suatu daerah sehingga perlu adanya perhatian khusus agar dapat mendorong perkembangan dan kemajuan pada sektor ini, khususnya kebudayaan dan pariwisata yang ada di Bengkulu. Bengkulu memiliki kebudayaan dan pariwisata yang beraneka ragam, baik wisata alam, wisata budaya dan wisata sejarahnya yang memiliki keistimewaan dan keunikan tersendiri yang harus dikembangkan dan dilestarikan. Namun hingga saat ini, informasi mengenai kebudayaan dan pariwisata di Provinsi Bengkulu masih belum terpublikasi dengan baik. Masih banyak wisatawan dan masyarakat yang belum mengetahui keragaman kebudayaan dan pariwisata yang ada di Provinsi Bengkulu. Sehingga dibutuhkan suatu inovasi baru dengan memanfaatkan teknologi berbasis web dengan membangun sistem Informasi pengenalan kebudayaan Bengkulu yang dinamakan SIPEDALU. Metode yang digunakan dalam pengembangan sistem ini yaitu metode Waterfall. Berdasarkan dari hasil pengujian yang dilakukan menggunakan Blackbox testing didapatkan akurasi sebesar 100% pada sistem informasi pengenalan kebudayaan dan pariwisata Provinsi Bengkulu.