bluuebunny/crossref_metadata_2025 huggingface dataset:
Prolonged Delayed Renal Graft Function Secondary to Venous Hypertension
Authors: Mishra Suraj , Gupta Gaurav , Moinuddin I. , Strife Brian , Prasad Uma , Massey D. , King Anne , Kumar Dhiren , Bhati Chandra S.
Published: September 2017

The case of a 39-year-old highly sensitized woman who underwent second renal transplantation after being on warfarin because of a history of frequent thromboses of her left femoral arteriovenous graft (AVG) is reported here. The patient received a flow cytometric positive crossmatch kidney transplant from a deceased donor. Her posttransplant course was complicated by prolonged delayed graft function (DGF) lasting for 9 months. Antibody-mediated rejection occurred in the immediate postoperative period. This resolved after treatment, and resolution was confirmed by repeat biopsy. Despite this, she had persistent DGF and remained dialysis dependent. A computed tomography scan due to the development of perinephric hematoma after posttransplant biopsy demonstrated venous collateralization around the allograft. At 7 months posttransplant, a venogram during declotting of AVG revealed chronic thrombus in the inferior vena cava (IVC) above the level of native renal veins with a venous gradient of 26 mmHg. After declotting of the graft, iliac venoplasty, and subsequent IVC stent, her renal function continues to improve with a most recent creatinine of 1.4 mg/dL at 36 months posttransplant. Venous hypertension secondary to IVC thrombosis in presence of patent femoral AVG should be considered as a rare cause of prolonged DGF.
Retrospective cell lineage reconstruction in Humans using short tandem repeats
Authors: Tao Liming , Raz Ofir , Marx Zipora , Gosh Manjusha , Huber Sandra , Greindl-Junghans Julia , Biezuner Tamir , Amir Shiran , Milo Lilach , Adar Rivka , Levy Ron , Onn Amos , Chapal-Ilani Noa , Berman Veronika , Arie Asaf Ben , Rom Guy , Oron Barak , Halaban Ruth , Czyz Zbigniew T. , Werner-Klein Melanie , Klein Christoph A. , Shapiro Ehud
Published: September 2017

Cell lineage analysis aims to uncover the developmental history of an organism back to its cell of origin1. Recently, novelin vivomethods and technologies utilizing genome editing enabled important insights into the cell lineages of animals2–8. In contrast, human cell lineage remains restricted to retrospective approaches, which still lack in resolution and cost-efficient solutions. Here we demonstrate a scalable platform for human cell lineage tracing based on Short Tandem Repeats (STRs) targeted by duplex Molecular Inversion Probes (MIPs). With this platform we accurately reproduced a known lineage of DU145 cell lines cells9and reconstructed lineages of healthy and metastatic single cells from a melanoma patient. The reconstructed trees matched the anatomical and SNV references while adding further refinements. Our platform allowed to faithfully recapitulate lineages of developmental tissue formation in cells from healthy donors. In summary, our lineage discovery platform can profile informative STR somatic mutations efficiently and we provide a solid, high-resolution lineage reconstruction even in challenging low-mutation-rate healthy single cells.
Ancient genomes from North Africa evidence prehistoric migrations to the Maghreb from both the Levant and Europe
Authors: Fregel Rosa , Méndez Fernando L. , Bokbot Youssef , Martín-Socas Dimas , Camalich-Massieu María D. , Santana Jonathan , Morales Jacob , Ávila-Arcos María C. , Underhill Peter A. , Shapiro Beth , Wojcik Genevieve , Rasmussen Morten , Soares Andre E. R. , Kapp Joshua , Sockell Alexandra , Rodríguez-Santos Francisco J. , Mikdad Abdeslam , Trujillo-Mederos Aioze , Bustamante Carlos D.
Published: September 2017

The extent to which prehistoric migrations of farmers influenced the genetic pool of western North Africans remains unclear. Archaeological evidence suggests the Neolithization process may have happened through the adoption of innovations by local Epipaleolithic communities, or by demic diffusion from the Eastern Mediterranean shores or Iberia. Here, we present the first analysis of individuals’ genome sequences from early and late Neolithic sites in Morocco, as well as Early Neolithic individuals from southern Iberia. We show that Early Neolithic Moroccans are distinct from any other reported ancient individuals and possess an endemic element retained in present-day Maghrebi populations, confirming a long-term genetic continuity in the region. Among ancient populations, Early Neolithic Moroccans are distantly related to Levantine Natufian hunter-gatherers (∼9,000 BCE) and Pre-Pottery Neolithic farmers (∼6,500 BCE). Although an expansion in Early Neolithic times is also plausible, the high divergence observed in Early Neolithic Moroccans suggests a long-term isolation and an early arrival in North Africa for this population. This scenario is consistent with early Neolithic traditions in North Africa deriving from Epipaleolithic communities who adopted certain innovations from neighbouring populations. Late Neolithic (∼3,000 BCE) Moroccans, in contrast, share an Iberian component, supporting theories of trans-Gibraltar gene flow. Finally, the southern Iberian Early Neolithic samples share the same genetic composition as the Cardial Mediterranean Neolithic culture that reached Iberia ∼5,500 BCE. The cultural and genetic similarities of the Iberian Neolithic cultures with that of North African Neolithic sites further reinforce the model of an Iberian migration into the Maghreb.

SIGNIFICANCE STATEMENT

The acquisition of agricultural techniques during the so-called Neolithic revolution has been one of the major steps forward in human history. Using next-generation sequencing and ancient DNA techniques, we directly test if Neolithization in North Africa occurred through the transmission of ideas or by demic diffusion. We show that Early Neolithic Moroccans are composed of an endemic Maghrebi element still retained in present-day North African populations and distantly related to Epipaleolithic communities from the Levant. However, late Neolithic individuals from North Africa are admixed, with a North African and a European component. Our results support the idea that the Neolithization of North Africa might have involved both the development of Epipaleolithic communities and the migration of people from Europe.
Streamlined histone-based fluorescence lifetime imaging microscopy reveals ATM regulation of chromatin compaction
Authors: Sherrard Alice , Bishop Paul , Panagi Melanie , Villagomez Maria Beatriz , Alibhai Dominic , Kaidi Abderrahmane
Published: September 2017

Changes in chromatin compaction are crucial during genomic responses. Thus, methods that enable such measurements are instrumental for investigating genome function. Here, we address this challenge by developing, validating, and streamlining histone-based fluorescence lifetime imaging microscopy (FLIM) that robustly detects chromatin compaction states in fixed and live cells; in 2D and 3D. We present quality-controlled and detailed method that is simpler and faster than previous approches, and uses FLIMfit open-source software. We demonstrate the versatility of our method through its combination with immunofluorescence and its implementation in immortalised cells and primary neurons. Owing to these developments, we applied this method to elucidate the function of the DNA damage response kinase, ATM, in regulating chromatin organisation after genotoxic-stress. We unravelled a role for ATM in regulating chromatin compaction independently of DNA damage. Collectively, we present an adaptable chromatin FLIM method for examining chromatin structure in cells, and establish its broader utility.
A novel strategy to express different antigens from one modified vaccinia Ankara vaccine vector
Authors: Lauer K. B. , McKenzie E. A. , Hall Y. , Gowda C.P.C. , Klapper P. , Borrow R. , Vallely P.J. , Carroll M. W. , Blanchard T. J.
Published: September 2017

To enhance global control of encephalitis and hepatitis caused by rabies-(RABV), Japanese encephalitis-(JEV), hepatitis B-virus (HBV), and enterovirus 71 (EV71) novel immunisation strategies are needed. Therefore, a multipathogen modified Vaccinia Ankara vector, expressing antigens from the above pathogens, was constructed. Two recombinants, one carrying the EV71 and JEV pathogen sequence and one the RABV-HBV pathogen sequence were generated. To ensure similar expression of the antigens, a T7-promoter was linked to the expression cassettes of all pathogen sequences. Direct regulation of this promoter was achieved through co-infection with a second T7-polymerase expressing MVA. Protein expression using this co-infection model of expression was demonstrated in vitro. To investigate the co-infection model of antigen delivery in vivo, a murine immunogenicity study was performed using the MVA-RABV-HBV recombinant. Although, serum antibodies against MVA were induced in all mice, no serum antibodies against RABV or HBV could be detected.
A structural approach to disentangle the visualization of bipartite biological networks
Authors: Garcia-Algarra J. , Pastor J. M. , Mouronte M. L. , Galeano J.
Published: September 2017

Interactions between two different guilds of entities are pervasive in biology. They may happen at molecular level, like in a diseasome, or amongst individuals linked by biotic relationships, such as mutualism or parasitism. These sets of interactions are complex bipartite networks. Visualization is a powerful tool to explore and analyse them but the most common plots, the bipartite graph and the interaction matrix, become rather confusing when working with real biological networks. We have developed two new types of visualization that exploit the structural properties of these networks to improve readability. A technique calledk-core decompositionidentifies groups of nodes that share connectivity properties. With the results of this analysis it is possible to build a plot based on information reduction (Polar Plot) and another which takes the groups as elementary blocks for spatial distribution (Ziggurat plot). We describe the applications of both plots and the software to create them.
Distributed and dynamic intracellular organization of extracellular information
Authors: Granados Alejandro A. , Pietsch Julian M. J. , Cepeda-Humerez Sarah A. , Tkačik Gašsper , Swain Peter S.
Published: September 2017

Although cells respond specifically to environments, how environmental identity is encoded intracellularly is not understood. Here we study this organization of information in budding yeast by estimating the mutual information between environmental transitions and the dynamics of nuclear translocation for ten transcription factors. Our method of estimation is general, scalable, and based on decoding from single cells. The dynamics of the transcription factors are necessary to encode the highest amounts of extracellular information, and we show that information is transduced through two channels: generalists (Msn2/4, Tod6/Dot6, Maf1, and Sfp1) can encode the nature of multiple stresses but only if stress is high; specialists (Hog1, Yap1, and Mig1/2) encode one particular stress, but do so more quickly and for a wider range of magnitudes. Each transcription factor reports differently, and it is only their collective response that distinguishes between multiple environmental states. Changes in the dynamics of the localization of transcription factors thus constitute a precise, distributed internal representation of extracellular change, and we predict that such multi-dimensional representations are common in cellular decision-making.

Significance Statement

To thrive in diverse environments, cells must represent extracellular change intracellularly despite stochastic biochemistry. Here we introduce a quantitative framework for investigating the organization of information within a cell. Combining single-cell measurements of intracellular dynamics with a new, scalable methodology for estimating mutual information between time-series and a discrete input, we demonstrate that extracellular information is encoded in the dynamics of the nuclear localization of transcription factors and that information is lost with alternative static statistics. Any one transcription factor is usually insufficient, but the collective dynamics of multiple transcription factors can represent complex extracellular change. We therefore show that a cell’s internal representation of its environment can be both distributed across diverse proteins and dynamically encoded.
USA300 MRSA lineages persist on multiple body sites following infection
Authors: Read Timothy D. , Petit Robert A. , Yin Zachary , Montgomery Tuyaa , McNulty Moira C. , David Michael Z.
Published: September 2017

Abstract

BACKGROUND

USA300 methicillin-resistantStaphylococcus aureus(MRSA) is a community- and hospital- acquired pathogen that frequently causes infections but also can survive on the human body asymptomatically as a part of the normal flora. We devised a comparative genomic strategy to track colonizing USA300 at different body sites afterS. aureusinfection.

METHODS

We sampled ST8S. aureusfrom subjects at the site of a first known MRSA infection. Within 60 days of this infection and again 12 months later, each subject was tested for asymptomatic colonization in the nose, throat and perirectal region. 93S. aureusstrains underwent whole genome shotgun sequencing.

RESULTS

Genome sequencing revealed that 23 patients carried USA300 intra-subject lineages (ISLs), defined as having an index infection isolate (III) and closely related strains. Pairwise distance between strains in different ISLs was 48 to 162 single nucleotide polymorphisms (SNPs), whereas within the same ISL it was 0 to 26 SNPs. At the initial sampling time among 23 subjects, we isolatedS. aureusfrom the nose, throat and perirectal sites from 15, 11 and 15 of them, respectively. Twelve months later we isolatedS. aureuswithin the same ISL from 9 subjects, with 6, 3 and 3 strains from the nose, throat and perirectal area, respectively. The median time from initial acquisition of theS. aureusUSA300 strains to culture of the index infection was estimated at 18 weeks. Strains in ISLs from the same subject differed in plasmid and prophage content, and contained deletions that removed themecA-containing SCCmecand ACME regions. Five strains contained frameshift mutations inagrtoxin-regulating genes. Persistence of an ISL was not associated with clinical or demographic subject characteristics.

CONCLUSION

Clonal lineages of USA300 may continue to colonize people at one or more anatomic sites up to a year after an initial infection and experience loss of the SCCmec, loss and gain of other mobile genetic elements, and mutations in the agr operon.
Pinaceae show elevated rates of gene duplication and gene loss that are robust to incomplete gene annotation
Authors: Casola Claudio , Koralewski Tomasz E.
Published: September 2017

Gene duplications and gene losses are major determinants of genome evolution and phenotypic diversity. The frequency of gene turnover (gene gains and gene losses combined) is known to vary between organisms. Comparative genomic analyses of gene families can highlight such variation; however, estimates of gene turnover rates may be biased when using highly fragmented genome assemblies resulting in poor gene annotations. Here, we address potential biases introduced by gene annotation errors in estimates of gene turnover frequencies in a dataset including both well-annotated angiosperm genomes and the incomplete gene sets of four Pinaceae including two pine species, Norway spruce and Douglas-fir. Previous studies have shown low overall substitution rates, but higher levels of adaptive substitutions, in genes from Pinaceae and other gymnosperms compared to angiosperms. Conversely, our analysis suggests that pines experienced higher gene turnover rates than angiosperm lineages lacking recent whole-genome duplications. This finding is robust to both known major issues in Pinaceae gene sets: missing gene models and erroneous annotation of pseudogenes. A separate analysis limited to the four Pinaceae gene sets confirmed an accelerated gene turnover rate in pines compared to Norway spruce and Douglas-fir. Our results indicate that gene turnover significantly contributes to genome variation and possibly to adaptation and speciation in Pinaceae. Moreover, these findings indicate that reliable estimates of gene turnover frequencies can be discerned in incomplete and potentially inaccurate gene sets.
Salient Experiences are Represented by Unique Transcriptional Signatures in the Brain
Authors: Mukherjee Diptendu , Ignatowska-Jankowska Bogna Marta , Itskovits Eyal , Gonzales Ben Jerry , Turm Hagit , Izakson Liz , Haritan Doron , Bleistein Noa , Cohen Chen , Amit Ido , Shay Tal , Grueter Brad , Zaslaver Alon , Citri Ami
Published: September 2017

Inducible transcription is essential for consolidation of salient experiences into long-term memory. However, the question of whether inducible transcription relays information representing the identity of the experience being encoded, has not been explored. To this end, we have analyzed transcription across multiple brain regions, induced by a variety of rewarding and aversive experiences. Our results define robust transcriptional signatures uniquely characterizing individual salient experiences. A subset of these induced transcriptional markers suffice for near-perfect decoding of the identity of recent experiences at the level of individual mice. Furthermore, experiences with shared attributes display commonalities in their transcriptional representation, exemplified in the representation of valence, habituation and reinforcement. Taken together, our results demonstrate the existence of a neural transcriptional code that represents the encoding of experiences in the mouse brain. This code is comprised of distinct transcriptional signatures that correlate to the affective attributes of the experiences that are being encoded.
Cryo-EM reconstruction of the chlororibosome to 3.2 Å resolution within 24 h
Authors: Forsberg Björn O. , Aibara Shintaro , Kimanius Dari , Paul Bijoya , Lindahl Erik , Amunts Alexey
Published: September 2017

The introduction of direct detectors and the automation of data collection in cryo-EM have led to a surge in data, creating new opportunities for advancing computational processing. In particular, on-the-fly workflows that connect data collection with three-dimensional reconstruction would be valuable for more efficient use of cryo-EM and its application as a sample-screening tool. Here, accelerated on-the-fly analysis is reported with optimized organization of the data-processing tools, image acquisition and particle alignment that make it possible to reconstruct the three-dimensional density of the 70S chlororibosome to 3.2 Å resolution within 24 h of tissue harvesting. It is also shown that it is possible to achieve even faster processing at comparable quality by imposing some limits to data use, as illustrated by a 3.7 Å resolution map that was obtained in only 80 min on a desktop computer. These on-the-fly methods can be employed as an assessment of data quality from small samples and extended to high-throughput approaches.
Merging single-shot XFEL diffraction data from inorganic nanoparticles: a new approach to size and orientation determination
Authors: Li Xuanxuan , Spence John C. H. , Hogue Brenda G. , Liu Haiguang
Published: September 2017

X-ray free-electron lasers (XFELs) provide new opportunities for structure determination of biomolecules, viruses and nanomaterials. With unprecedented peak brilliance and ultra-short pulse duration, XFELs can tolerate higher X-ray doses by exploiting the femtosecond-scale exposure time, and can thus go beyond the resolution limits achieved with conventional X-ray diffraction imaging techniques. Using XFELs, it is possible to collect scattering information from single particles at high resolution, however particle heterogeneity and unknown orientations complicate data merging in three-dimensional space. Using the Linac Coherent Light Source (LCLS), synthetic inorganic nanocrystals with a core–shell architecture were used as a model system for proof-of-principle coherent diffractive single-particle imaging experiments. To deal with the heterogeneity of the core–shell particles, new computational methods have been developed to extract the particle size and orientation from the scattering data to assist data merging. The size distribution agrees with that obtained by electron microscopy and the merged data support a model with a core–shell architecture.
Short-sale prohibitions, firm characteristics and stock returns: evidence from Chinese market
Authors: Li Rui , Li Jiahui , Yuan Jinjian
Published: September 2017

Purpose

The purpose of this paper is to empirically analyze the impacts of short prohibitions on stock prices.

Design/methodology/approach

The authors adopt event study in this paper. First, the authors match each shortable stocks with one unshortable stocks by the propensity score matching method. Second, the authors check the performance difference between treatment group and control group after the event date. Third, the authors check the performance difference among sub-groups sorted by other factors associated with stock returns.

Findings

The authors find that stocks do not decline necessarily after removal of short prohibitions; only those heavily overpriced stocks, such as small stocks, lower B/M or P/E stocks and higher turnover stocks, decline significantly.

Research limitations/implications

The media falsely stated that short selling lead to market crash; otherwise, short selling is beneficial for improving market efficiency as it is helpful for keeping overpriced stocks in line with the fundamental value.

Originality/value

This is the first paper showing that removal of short prohibitions only impacts heavily overpriced stocks significantly, which is valuable for policy making.
Ethnically diverse workplaces in Irish hospitals
Authors: Bobek Alicja , Devitt Camilla
Published: September 2017

Purpose

The purpose of this paper is to explore the ethnically diverse workplace in Irish hospitals by examining the perspectives of foreign- and Irish-born professionals and their managers.

Design/methodology/approach

Semi-structured qualitative interviews with 30 health professionals (foreign- and Irish-born) and with hospital managers (Irish-born). All interviews were transcribed and analysed using thematic analysis.

Findings

The managers and professionals interviewed mostly perceived ethnically diverse workplaces as an asset. Health professionals also identified a number of challenges, including internal divisions based on ethnicity, language and communication problems and cultural differences. However, in general, discrimination on the basis of ethnicity was not highlighted by interviewees.

Research limitations/implications

While the qualitative design of the study allowed for an in-depth exploration of experiences in ethnically diverse workplaces in selected Irish hospitals, the relatively small sample size poses some limitations. The study brings to light the need for larger-scale survey-based research on the ethnically diverse workplace in Irish hospitals, which includes Irish- and foreign-born health professionals in the sample.

Originality/value

The study includes a variety of perspectives on experiences in ethnically diverse workplaces in Irish hospitals, including foreign-born health professionals, their Irish-born colleagues and hospital managers.
Relationships between job embeddedness and employees’ life satisfaction
Authors: Ampofo Emmanuel Twumasi , Coetzer Alan , Poisat Paul
Published: September 2017

Purpose

The purpose of this paper is to explore relationships between organisation embeddedness and life satisfaction, and community embeddedness and life satisfaction. The study also examined relationships between each sub-dimension of organisation embeddedness and community embeddedness and life satisfaction. These sub-dimensions are “links”, “fit” and “sacrifice”.

Design/methodology/approach

Data were collected from 549 employees in organisations located in four major business centres in South Africa. The data were analysed using structural equation modelling.

Findings

Both organisation embeddedness and community embeddedness were positively related to life satisfaction. Regarding the sub-dimensions of organisation embeddedness, only organisation fit and sacrifice were positively related to life satisfaction. As regards the sub-dimensions of community embeddedness, only community fit was positively related to life satisfaction.

Practical implications

Adopting practices which embed employees in the organisation and communities where they live is potentially beneficial for both organisations and employee well-being.

Originality/value

The bulk of research on job embeddedness (JE) and work-related outcomes has focussed on benefits for the organisation. The effects of embeddedness on employee well-being have been largely overlooked. The current study is an attempt to redress this imbalance in JE research.
Lay off employees or terminate consultant contracts? Responses to an external shock in three firms in the Norwegian petroleum industry
Authors: Fijalkowska Anna Paula , Hjartåker Karina Sofie , Nesheim Torstein
Published: September 2017

Purpose

Previous studies on non-standard employment relations have analyzed how firms’ use of non-standard work arrangements are explained by variables related to numerical flexibility. Here, the purpose of this paper is to explore how firms respond to changes in the external environment through reduction in staffing. Since the firms combine employees and external consultants, they are confronted with a dilemma between laying off employees or terminating consultant contracts.

Design/methodology/approach

The empirical context is the petroleum sector in Norway. The data consists of 11 interviews with managers at different levels in three firms.

Findings

The authors found that firms terminated over 80 percent of the consultant contracts, while around a forth of employees were downsized. A core-periphery strategy and union power are vital drivers of the prioritization of employees. However, some consultants were retained due to their knowledge of unique aspects of the firm and their role in development and innovation. The authors also found that the firms differed in their emphasis on seniority vs competencies criteria in deciding “survival” among employees.

Research limitations/implications

A main contribution of the study is thus the identification of variables and mechanisms that influence the two interrelated choices of downsizing in such multi-employment contexts. The main limitation is the number of firms analyzed (three), which restricts statistical generalization.

Practical implications

Better understanding of circumstances and criteria of downsizing choices in employees/external consultants’ constellations.

Originality/value

This study is one of the first to analyze two interrelated issues of downsizing in such constellations lying off employees vs terminating consulting contracts, and whether seniority or competence criteria were prioritized when laying off employees. A main contribution of the study is the identification of variables and mechanisms that influence the two interrelated choices of downsizing in such multi-employment contexts.
Exploring the role of employer forums – the case of Business in the Community Wales
Authors: Bowkett Cassandra , Hauptmeier Marco , Heery Edmund
Published: September 2017

Purpose

Collective employer representation in the UK has changed in fundamental ways in recent decades. Collective bargaining has declined and instead, the authors have seen the emergence of a significant new form of collective organisation, the employer forum (EF), which promotes good corporate behaviour and typically focusses on issues of equality and diversity, social policy and community engagement. The purpose of this paper is to examine this new form of collective action through a case study on Business in the Community (BITC) Wales. It also compares this EF with traditional employers’ associations (EAs) in order to establish what is significant and distinctive about EFs.

Design/methodology/approach

BITC Wales is a “typical case” (Patton, 2014; Seawright and Gerring, 2008) that shares key characteristics and functions with other EFs across key analytical dimensions, and therefore provides insights into the wider population of EFs in the UK. In addition, the paper compares EFs, examined through a qualitative case study of BITC Wales, and traditional EAs, introduced and discussed in the literature review, along the same analytical dimensions. The aim of contrasting EAs with the case study on BITC Wales is to establish what is distinctive and significant about EFs and to consider the implications for employment relations in the UK.

Findings

The paper argues that EFs and EAs support employers in dealing with the challenges of managing the employment relationship and threats to profitability in different political contexts. The organisation of employers in EAs was a response to increasing trade union power and labour costs. EFs are helping employers to deal with a different set of challenges, including declining social cohesion in communities in which employers operate, reputational and legal risks posed by new equality and diversity legislation and expectations of good corporate citizenship by consumers and their own employees. EFs address these challenges by engaging in social projects in local communities, by promoting good corporate behaviour through benchmarking and codes of conduct, and by boosting the reputation of employers through award schemes and promotion of corporate social responsibility activities of member companies.

Originality/value

Previous literature has not examined EFs and their role in employment relations. This paper considers EFs as a new actor in employment relations.
Institutional logics perspective in management control research
Authors: Damayanthi Sujeewa , Gooneratne Tharusha
Published: September 2017

Purpose

This paper reviews management control literature which draws on the institutional logics perspective as the theoretical lens to understand the current grounding of this perspective on management control research. It identifies gaps in the current literature and offers possible future research directions.

Design/methodology/approach

For the purpose of this paper, five search engines (ABI INFORM, EBSCO, Emerald insight, JSTOR and Science Direct) were consulted, and 35 papers across 16 journals, which specifically fall within the area of management controls and institutional logics, were reviewed.

Findings

The review revealed that the institutional logics perspective has provided theoretical anchoring to management control-related areas such as budgeting, performance management and control tools in organizations. The extant studies have either used institutional logics as a single theoretical perspective or have integrated it with other theories such as neo-institutional theory, agency theory and structuration theory. The research settings of the papers span across firm level, industry level and government organizations and non-profit organizations. Most of the studies have used the qualitative case study approach, whereas a few have taken the mixed method research design.

Originality/value

Although there are a number of review papers in the area of management controls as well as on institutional theory in general, such reviews have not specifically been focused on the institutional logics perspective, which is a significant development within institutional theory, having provided theoretical backing to a wide range of management control studies over the years. Addressing this omission, this paper provides important insights for future researchers on what research has been done using the lens of institutional logics and what else is worth doing. In that sense, this paper contributes to the domain of management control research, as well as to the development of institutional theory in general and the institutional logics perspective in particular.
The indirect effect of strategic management accounting in the relationship between CEO characteristics and their networking activities, and company performance
Authors: Amanollah Nejad Kalkhouran Abolfazl , Hossein Nezhad Nedaei Bahareh , Abdul Rasid Siti Zaleha
Published: September 2017

Purpose

The purpose of this paper is to investigate the effect of chief executive officer (CEO) characteristics and involvement in networks on strategic management accounting (SMA) and, in turn, the indirect effect of SMA on company performance.

Design/methodology/approach

A model is advanced and tested using partial least-squares path modelling and data were collected from a sample of 121 service small and medium-sized enterprises (SMEs) in Malaysia.

Findings

The results indicate significant and positive relationships between the CEO education and the application of SMA as well as between involvement in networks and SMA. Moreover, it is found that SMA has an indirect effect in relations of CEO education, involvement in networks and company performance.

Practical implications

SMEs’ leaders may realize their important role in affecting outcomes by their choices, which are in turn affected by their characteristics and activities.

Originality/value

This study provides an empirical evidence on the impact of two new factors on the SMA by considering contingency theory and upper echelons theory simultaneously for explaining relationships and developing a new model.
Disclosure effects of the PCAOB part II reports
Authors: Udeh Ifeoma
Published: September 2017

Purpose

The purpose of this paper is to examine the effect of the PCAOB part II report disclosures on US triennially inspected audit firms’ deregistration decisions, the likelihood and the timing of audit firms’ dismissals and resignations.

Design/methodology/approach

The paper anchored on US regulations used 158 publicly available records of disclosed PCAOB part II reports from 2004 to 2012.

Findings

The number of the quality control deficiencies disclosed in the part II report affects US triennially inspected audit firms’ decisions to deregister from the PCAOB. Additionally, audit firms’ dismissals and resignations, both occur mostly within the first year after the part II report disclosure, although audit firms that subsequently deregister are more likely to be dismissed.

Practical implications

The paper provides support that the disclosure of the PCAOB part II inspection report motivates audit quality improvement.

Social implications

The PCAOB inspection and subsequent disclosure of the part II inspection report enhances audit quality, which in turn, enhances investor confidence in the accuracy and reliability of audited financial statements.

Originality/value

The paper provides insights about the effect of the disclosures of PCAOB part II report, over and above any benefits from the PCAOB part I report disclosures, which is the dominant focus of related literature.
The relationship between customer orientation, emotional labour and job burnout
Authors: Wu Xue , Shie An-Jin
Published: September 2017

Purpose

Drawing on the conservation of resources theory, this study aims to apply the emotional labour concept to illustrate about the relationship between customer orientation (CO) and job burnout, further demonstrating how the relationship is established in the hospitality industry. This study intends to find that emotional intelligence moderates the relationship between CO and emotional labour.

Design/methodology/approach

The study uses descriptive statistical analysis and reliability analysis. Then, the study uses confirmatory factor analyses to ensure the model fit and discriminant validity of the measures. Finally, the hypothesised relationship model is tested and analysed via regression analysis.

Findings

The study finds three dimensions of emotional labour all partially mediated the relationship between CO and job burnout. Meanwhile, the study finds that emotional intelligence would moderate the relationship between CO and three dimensions of emotional labour.

Research limitations/implications

First, the respondents in this study come from five-star hotels in Beijing, China. As the results of this study are based on a sample of Chinese five-star hotel employees, the selection of a single service setting and a single country may raise concerns for the issue of generalisability. Thus, the findings of this study may not generalise to other hospitality contexts, other cultures or other times; research in other settings, geographical areas or times might yield different results.

Practical implications

High employee job burnout is a thorny problem in the hospitality industry, so it is a great challenge for hospitality management to solve high employee job burnout. As a personality resource, CO will decrease job burnout. Emotional labour is a common issue in hospitality. The study intends to explore the lived experiences of the frontline employees in hospitality industry to explain the role of CO directives on employee job burnout in an emotional labour perspective. The results give suggestions for the hospitality management.

Social implications

After reviewing of relevant literature, two research gaps are found. First, despite the amount of research showing a negative relationship between CO and job burnout, remarkably little is known about how these relationships are established. Second, a more important gap lies in overlooking the emotional nature of hospitality service work. The results of the study can fill the theoretical gap.

Originality/value

First, the recruitment and selection of frontline employees should incorporate an assessment of the level of CO. Second, hospitality management should teach and train the employees about the proper control of emotional labour. Third, the recruitment and selection of frontline employees should incorporate an assessment of the level of emotional intelligence; meanwhile, it is necessary to strengthen the emotional intelligence training.
Preparing junior doctors for emergency psychiatric experience: a peer-led teaching programme
Authors: Till Alex , Shaw Elizabeth Jane , Royles Bethan , Banat Malik , Singh Krishna , Wilson Peter , Vinjamuri Indira
Published: September 2017

Purpose

Junior doctors rotating through psychiatry often practise in isolated environments with little prior experience in this field. This can cause anxiety amongst doctors, and may potentially lead to patient safety concerns. The paper aims to discuss these issues.

Design/methodology/approach

A novel peer-led simulation style teaching session was developed to improve junior doctor knowledge and confidence when working with psychiatry rotations out of hours.

Findings

Following successful completion of two iterations of the teaching, junior doctors reported increased confidence, reduced anxiety and a more positive attitude following the session. Facilitators were similarly positive in their feedback, being able to gain formal teaching experience and appraisal.

Originality/value

A novel, inexpensive and easily replicable teaching session is introduced, which can improve junior doctors’ practice and experience when working in psychiatry settings out of hours.
It is your fault! How blame attributions of breach predict employees’ reactions
Authors: Costa Sandra , Neves Pedro
Published: September 2017

Purpose

Using insights from attributions, planned behavior, and fairness theories, this study examines the effect of blame attributions of psychological contract breach on employees’ attitudes (affective organizational commitment) and behaviors (organizational citizenship behavior (OCB)). The purpose of this paper is to understand whether employees’ reactions depend on the attributions they make concerning who is responsible for the breach.

Design/methodology/approach

Cross-lagged design in which data were collected from 220 employees and their supervisors in a public company at two times. Moderated mediation was tested using the bootstrapping analysis outlined by Hayes (2012).

Findings

The results supported the authors’ predictions: employees’ blame attributions to the organization have a negative impact on OCBs (as rated by supervisors in time 2) through decreased affective organizational commitment, but blame attributions to the economic context act as a buffer to the relationship between blame attributions to organization and affective organizational commitment, with consequences for OCBs.

Research limitations/implications

Attributions can also be made to concrete persons (i.e. supervisor, coworker, self) rather than to just the organization or context.

Practical implications

When hiring, recruiters should provide accurate and realistic promises to the candidates. When facing hard times, managers should provide additional information to employees and adjust their expectations to the current situation of the firm.

Originality/value

This study makes a unique contribution to the literature by questioning the “single story” perspective about reactions to psychological contract breach, in which it is assumed that employees always respond negatively to such event.
Competing in business-to-business sectors through pay-per-use services
Authors: Gebauer Heiko , Haldimann Mirella , Saul Caroline Jennings
Published: September 2017

Purpose

Despite the opportunities provided by pay-per-use (PPU) services, product companies in business-to-business sectors often fail to compete systematically by using them. The purpose of this paper is to explain how companies can avoid failures when it comes to PPU services. The paper describes the “seizing” capabilities needed to achieve the strategic objectives of PPU services.

Design/methodology/approach

The research process is divided into a pilot and an in-depth study. Altogether, 17 companies participated in the study.

Findings

The findings reveal that the seizing capabilities depend on the strategic objectives of PPU services. To expand the market share with PPU services, companies need to broaden the customer portfolio for PPU services, to align individual services within the entire service portfolio and to balance profits made by PPU services and other business lines. For strategic objectives such as rapid sales growth early in the market development and new market creation other seizing capabilities are required.

Research limitations/implications

The findings are not generalizable, due to the use of a qualitative study. The study is restricted to product companies in the business-to-business sector.

Practical implications

Managers often believe that extending and modularizing the service portfolio is beneficial. When achieving sales growth during the market development phase, these capabilities are in fact sometimes counterproductive. Practitioners have to look into the costs and benefits of setting-up their own financing company and working with banks.

Social implications

PPU services contribute to a more sustainable consumption and make product design more resource-efficient.

Originality/value

The study is original by virtue of systematically studying PPU services, providing a microfoundation for seizing capabilities and developing testable propositions for future research.
Use of new technologies in libraries globally: a study
Authors: Sanjeev Sanjeev
Published: September 2017

Purpose

The present paper aims to explore the applications of new technologies in library scenario.

Design/methodology/approach

Survey method was used.

Findings

With the influx of information technology, libraries have engaged major deal of works on computers, which has nothing to do with the mission and objectives of the libraries. In such a situation, cloud computing has a lot on offer.

Originality/value

The present paper explores the core competencies of cloud-based computing and discusses about the cloud models-based futuristic libraries.
“Through the looking glass: envisioning new library technologies” Adopting augmented reality: trends and updates
Authors: Fernandez Peter
Published: September 2017

Purpose

This column aims to summarize developments in augmented reality and use those developments to help explain trends that influence the likelihood of mainstream adoption.

Design/methodology/approach

The idea of augmented reality also drives the development of many other related technologies, including wearables, haptic technologies and many others that have been featured in this column.

Findings

Developers invest in the future based on the idea that widespread use of augmented reality is just around the corner. Yet in many ways, it still appears to be a technology eternally on the cusp of mainstream adoption.

Originality/value

In 2014, this column looked at augmented reality as an important emerging technology. Nearly three years later, some libraries continue to use it in groundbreaking ways, and it has grown by leaps and bounds.
The determinants of internet risk disclosure: empirical study of Egyptian listed companies
Authors: Khalil Ali , Maghraby Mona
Published: September 2017

Purpose

The purpose of this paper is to contribute to the existing disclosure literature by examining the determinants of corporate risk disclosure (CRD) in the internet reporting for a sample of Egyptian listed companies on the Egyptian Stock Exchange (EGX).

Design/methodology/approach

This study depends on a sample of 76 Egyptian companies included in the EGX 100 in the period 2012-2014. The study applies a content analysis and uses a sentence-based method to measure CRD in the internet reporting. Ordinary least-squares regression analysis is used to examine the impact of firm and board characteristics on CRD in the internet reporting.

Findings

The empirical analysis shows that large Egyptian companies tend to disclose more risk information in their internet reporting. Moreover, the results indicate that there is a significant positive association between sector type and CRD in the internet reporting. The results show non-significant association between CRD and other firm characteristics (cross listing and level of risk). Finally, there are no significant associations between CRD and board characteristics variables (board size, board composition and CEO duality).

Research limitations/implications

The study’s findings have practical implications. It aids in informing policy makers considering implementing new economic reform programs about the properties of Egyptian companies that disclose risk information in their internet reporting. It provides insights on CRD in Egyptian companies for standards setters and professional authorities to improve risk reporting practices to help stakeholders in making good decisions.

Originality/value

This study is one of the first studies to examine the determinants of CRD in the internet reporting for a sample of Egyptian companies.