bluuebunny/crossref_metadata_2025 huggingface dataset:
Agricultural development driven by the digital economy: improved EfficientNet vegetable quality grading
Authors: Wen Jun , He Jing
Published: January 2024

Introduction

The conventional manual grading of vegetables poses challenges that necessitate innovative solutions. In this context, our paper proposes a deep learning methodology for vegetable quality grading.

Methods

To address the scarcity of vegetable datasets, we constructed a unique dataset comprising 3,600 images of diverse vegetables, including lettuce, broccoli, tomatoes, garlic, bitter melon, and Chinese cabbage. We present an improved CA-EfficientNet-CBAM model for vegetable quality grading. The CA module replaces the squeeze-and-excitation (SE) module in the MobileNet convolution (MBConv) structure of the EfficientNet model. Additionally, a channel and spatial attention module (CBAM) is integrated before the final layer, accelerating model training and emphasizing nuanced features.

Results

The enhanced model, along with comparisons to VGGNet16, ResNet50, and DenseNet169, was subjected to ablation experiments. Our method achieved the highest classification accuracy of 95.12% on the cabbage vegetable image test set, outperforming VGGNet16, ResNet50, and DenseNet169 by 8.34%, 7%, and 4.29%, respectively. Notably, the proposed method effectively reduced the model’s parameter count.

Discussion

Our experimental results highlight the effectiveness of the deep learning approach in improving vegetable quality grading accuracy. The superior performance of the enhanced EfficientNet model underscores its potential for advancing the field, achieving both high classification accuracy and parameter efficiency. We hope this aligns with your expectations. If there are further adjustments or clarifications needed, please let us know.
Research on the Stability and Bifurcation Characteristics of a Landing Gear Shimming Dynamics System
Authors: Ruan Shuang , Zhang Ming , Yang Shaofei , Hu Xiaohang , Nie Hong
Published: January 2024

A dynamic model is established to investigate the shimmy instability of a landing gear system, considering the influence of nonlinear damping. The stability criterion is utilized to determine the critical speed at which the landing gear system becomes unstable. The central manifold theorem and canonical method are employed to simplify the dynamic model of the landing gear. The first Lyapunov coefficient of the system is theoretically derived and verified using numerical simulation. Further investigation on the Hopf bifurcation characteristics and stability of the shimmy in the landing gear system is conducted. The results indicate that above a certain threshold speed, with a tire stability distance greater than half the tire length in contact with the ground plus the slack length, the aircraft remains stable during taxiing. At critical speeds, a shimmy system with higher-order nonlinear damping will undergo supercritical Hopf bifurcation. Quantitative analysis suggests an increase in the linear damping coefficient within a range that ensures a stability margin to mitigate undesired oscillation, while the nonlinear damping coefficient should be designed within a reasonable range to decrease the amplitude of the limit cycle.
A High-Efficiency DC-DC Converter Based on Series/Parallel Switched Inductor Capacitors for Ultra-High Voltage Gains
Authors: Algamluoli Ammar Falah , Wu Xiaohua
Published: January 2024

A high-efficiency DC-DC converter employing a modified architecture called the hybrid switched inductor–capacitor series (MHSLCS) is proposed in this paper. The primary goal is to achieve a notably ultra-high voltage gain for renewable energy systems (RESs). Furthermore, the use of only one input capacitor in the MHSLCS eliminates pulsations in the input current at both low and high duty ratios. The proposed converter integrates the MHSLCS with a modified switched capacitor (MSC) that interleaves with the main MOSFET, effectively doubling the voltage transfer gain. Additionally, a modified hybrid switched inductor–capacitor parallel (MHSLCP) is incorporated in parallel with an interleaved auxiliary MOSFET. Both MOSFETs, combined with the MSC, contribute to achieving an ultra-high voltage gain. In addition, the inductors of the MHSLCP operate in a discontinuous conduction mode (DCM), which results in significant stress reductions in the power diodes and switches at high output voltages. The advantages of the proposed converter are multifaceted, demonstrating a high efficiency while minimizing the voltage in power device diodes and MOSFETs. The use of low inductance and capacitance values at high switching frequencies further enhances the performance. Wide-bandgap (WBG) power devices are employed to achieve the desired high voltage gain and efficiency. The proposed converter was designed with a PCB and underwent experimental testing to validate laboratory results. The proposed converter boosted the input voltage from 30 V to a variable output voltage between 325 V and 500 V, with a power output of 325 watts and an efficiency of 95.5%.
On Automated Object Grasping for Intelligent Prosthetic Hands Using Machine Learning
Authors: Odeyemi Jethro , Ogbeyemi Akinola , Wong Kelvin , Zhang Wenjun
Published: January 2024

Prosthetic technology has witnessed remarkable advancements, yet challenges persist in achieving autonomous grasping control while ensuring the user’s experience is not compromised. Current electronic prosthetics often require extensive training for users to gain fine motor control over the prosthetic fingers, hindering their usability and acceptance. To address this challenge and improve the autonomy of prosthetics, this paper proposes an automated method that leverages computer vision-based techniques and machine learning algorithms. In this study, three reinforcement learning algorithms, namely Soft Actor-Critic (SAC), Deep Q-Network (DQN), and Proximal Policy Optimization (PPO), are employed to train agents for automated grasping tasks. The results indicate that the SAC algorithm achieves the highest success rate of 99% among the three algorithms at just under 200,000 timesteps. This research also shows that an object’s physical characteristics can affect the agent’s ability to learn an optimal policy. Moreover, the findings highlight the potential of the SAC algorithm in developing intelligent prosthetic hands with automatic object-gripping capabilities.
Phenomena of Intussusceptive Angiogenesis and Intussusceptive Lymphangiogenesis in Blood and Lymphatic Vessel Tumors
Authors: Díaz-Flores Lucio , Gutiérrez Ricardo , González-Gómez Miriam , García Maria del Pino , Carrasco-Juan Jose-Luis , Martín-Vasallo Pablo , Madrid Juan Francisco , Díaz-Flores Lucio
Published: January 2024

Intussusceptive angiogenesis (IA) and intussusceptive lymphangiogenesis (IL) play a key role in the growth and morphogenesis of vessels. However, there are very few studies in this regard in vessel tumors (VTs). Our objective is to assess the presence, characteristics, and possible mechanisms of the formation of intussusceptive structures in a broad spectrum of VTs. For this purpose, examples of benign and malignant blood and lymphatic VTs were studied via conventional procedures, semithin sections, and immunochemistry and immunofluorescence microscopy. The results demonstrated intussusceptive structures (pillars, meshes, and folds) in benign (lobular capillary hemangioma or pyogenic granuloma, intravascular papillary endothelial hyperplasia or Masson tumor, sinusoidal hemangioma, cavernous hemangioma, glomeruloid hemangioma, angiolipoma, and lymphangiomas), low-grade malignancy (retiform hemangioendothelioma and Dabska tumor), and malignant (angiosarcoma and Kaposi sarcoma) VTs. Intussusceptive structures showed an endothelial cover and a core formed of connective tissue components and presented findings suggesting an origin through vessel loops, endothelialized thrombus, interendothelial bridges, and/or splitting and fusion, and conditioned VT morphology. In conclusion, the findings support the participation of IA and IL, in association with sprouting angiogenesis, in VTs, and therefore in their growth and morphogenesis, which is of pathophysiological interest and lays the groundwork for in-depth molecular studies with therapeutic purposes.
Low-Temperature Calcium Phosphate Ceramics Can Modulate Monocytes and Macrophages Inflammatory Response In Vitro
Authors: Minaychev Vladislav V. , Smirnova Polina V. , Kobyakova Margarita I. , Teterina Anastasia Yu. , Smirnov Igor V. , Skirda Vladimir D. , Alexandrov Artem S. , Gafurov Marat R. , Shlykov Mikhail A. , Pyatina Kira V. , Senotov Anatoliy S. , Salynkin Pavel S. , Fadeev Roman S. , Komlev Vladimir S. , Fadeeva Irina S.
Published: January 2024

Creating bioactive materials for bone tissue regeneration and augmentation remains a pertinent challenge. One of the most promising and rapidly advancing approaches involves the use of low-temperature ceramics that closely mimic the natural composition of the extracellular matrix of native bone tissue, such as Hydroxyapatite (HAp) and its phase precursors (Dicalcium Phosphate Dihydrate—DCPD, Octacalcium Phosphate—OCP, etc.). However, despite significant scientific interest, the current knowledge and understanding remain limited regarding the impact of these ceramics not only on reparative histogenesis processes but also on the immunostimulation and initiation of local aseptic inflammation leading to material rejection. Using the stable cell models of monocyte-like (THP-1ATRA) and macrophage-like (THP-1PMA) cells under the conditions of LPS-induced model inflammation in vitro, the influence of DCPD, OCP, and HAp on cell viability, ROS and intracellular NO production, phagocytosis, and the secretion of pro-inflammatory cytokines was assessed. The results demonstrate that all investigated ceramic particles exhibit biological activity toward human macrophage and monocyte cells in vitro, potentially providing conditions necessary for bone tissue restoration/regeneration in the peri-implant environment in vivo. Among the studied ceramics, DCPD appears to be the most preferable for implantation in patients with latent inflammation or unpredictable immune status, as this ceramic had the most favorable overall impact on the investigated cellular models.
Action of Curcumin on Glioblastoma Growth: A Systematic Review with Meta-Analysis of Animal Model Studies
Authors: Luís Ângelo , Amaral Leonor , Domingues Fernanda , Pereira Luísa , Cascalheira José Francisco
Published: January 2024

Gliomas are aggressive brain tumors with poor prognosis even after surgical removal and radio-chemotherapy, stressing the urgency to find alternative therapies. Several preclinical studies evaluating the anticancer effect of curcumin in animal models of glioma are reported, but a systematic review with meta-analysis of these studies, considering the different experimental conditions used, has not been made up to this date. A search in different databases (Pubmed, Web of Science, Scopus, and SciELO) following the PRISMA statement was conducted during November 2023 to systematically identify articles assessing the effect of curcumin in murine xenograft models of glioma and identified 15 articles, which were subdivided into 24 studies. Tumor volume before and after treatment with curcumin or vehicle was extracted and the efficacy of curcumin was evaluated by performing a random effects meta-analysis of the data. Publication bias and the impact of different experimental conditions on curcumin efficacy were assessed. Treatment with curcumin decreased tumor volume. Comparing curcumin with control groups, the overall weighted standardized difference in means was −2.079 (95% CI: −2.816 to −1.341; p-value < 0.001). The curcumin effect was observed for different animal models, types of glioma cells, administration routes, and curcumin formulations. Publication bias was identified but does not invalidate curcumin’s effectiveness. The findings suggest the potential therapeutic efficacy of curcumin against glioma.
Amorphous Metallic Cobalt-Based Organophosphonic Acid Compounds as Novel Photocatalysts to Boost Photocatalytic CO2 Reduction
Authors: Zhou Chengwei , Wu Fan , Tang Yonggong , Chai Boyuan , Liang Jiaxin , Han Jiangang , Xing Weinan , Huang Yudong , Wu Guangyu
Published: January 2024

Photocatalytic carbon dioxide conversion is a promising method for generating carbon fuels, in which the most important thing is to adjust the catalyst material to improve the photocatalytic efficiency and selectivity to conversion products, but it is still very challenging. In order to enhance the efficiency of CO2 photoreduction, it is important to develop an appropriate photocatalyst. The present study focuses on developing a simple and effective hydrothermal reaction treatment to improve the catalytic efficiency of transition metal cobalt (Co) and organophosphonates. Photoexcited charge carriers are separated and transferred efficiently during this treatment, which enhances CO2 chemisorption. Under visible light exposure, the best performing catalyst, CoP-4, showed 2.4 times higher activity than Co3O4 (19.90 μmol h−1 g−1) for reducing CO2 into CO, with rates up to 47.16 μmol h−1 g−1. This approach provides a viable route to enhancing the efficiency of CO2 photoreduction.
Family Meal Environment Differentially Conditions the Prospective Association between Early Childhood Screen Time and Key Social Relationships in Adolescent Girls
Authors: Harandian Kianoush , Necsa Beatrice , Barnett Tracie A. , Pagani Linda S.
Published: January 2024

Background: Despite screen time recommendations, children are increasingly spending time on electronic devices, rendering it an important risk factor for subsequent social and developmental outcomes. Sharing meals could offer a way to promote psychosocial development. This study examines the interaction between family meal environment and early childhood screen time on key adolescent social relationships. Methods: Participants are 1455 millennial children (49% boys) from the Quebec Longitudinal Study of Child Development birth cohort. Parents reported on child screen use at ages 2 and 6 years and family meal environment quality at age 6 years. Parents and children reported on parent–child relationships and peer victimization experiences, respectively, at age 13 years. Sex-stratified multiple regression estimated the direct association between screen time trends, family meal environment quality, and their interaction on later social relationship outcomes. Results: For girls, when preschool screen time increased, sharing family meals in high-quality environments was associated with more positive and less conflictual relationships with their mothers, whereas meals shared in low- and moderate-quality environments were associated with fewer instances of victimization by their peers. Non-linear associations were not significant for boys. Conclusion: Capitalizing on family meal environment represents a simple/cost-efficient activity that can compensate for some long-term risks associated with increased screen use, above and beyond pre-existing and concurrent individual and family characteristics. Public health initiatives may benefit from considering family meals as a complementary intervention strategy to screen use guidelines.
Analysis of General Knowledge on Obstructive Sleep Apnea Syndrome (OSAS) among Italian Pediatricians
Authors: Saran Stefano , Saccomanno Sabina , Viti Simonetta , Mastrapasqua Rodolfo Francesco , Viti Grazia , Giannotta Nicola , Fioretti Paola , Lorenzini Elisa , Raffaelli Luca , Levrini Luca
Published: January 2024

Introduction: Obstructive sleep apnea syndrome (OSAS) is a disorder characterized by partial or total airway obstruction during sleep. Studies have shown variability in the level of knowledge and awareness about OSAS among pediatricians. The management of childhood obstructive sleep apnea syndrome (OSAS) depends on the severity of the disease, the presence of comorbidities, and the child’s age. The American Pediatric Academy recommends a multidisciplinary approach involving a pediatrician, a sleep specialist, and an otolaryngologist to provide comprehensive care for children with OSAS. The aim of this cross-sectional study is to evaluate the level of knowledge among pediatricians in Italy regarding the diagnosis of pediatric OSAS. Material and Methods: An anonymized survey was conducted among Italian pediatricians. The survey was administered electronically using Google Forms, and a total of 350 pediatricians were invited to participate. Out of the 350 invitations, 299 pediatricians responded to the survey. The statistical analysis performed consisted of descriptive analysis. The study included 297 pediatricians. Results: Pediatricians demonstrated proficiency in identifying common nocturnal and day symptoms of OSAS. A majority (68.9%) considered the oral and otorhinolaryngologist areas during checkups. Approximately 70.6% took patient weight into account, and 62.8% were aware of the regional diagnostic-therapeutic-assistance pathway. Conclusions: According to the results of this manuscript, there is evidence of a good level of knowledge about OSAS, but disseminating more information about OSAS and all the health issues associated with this syndrome is suggested. This study also has limitations caused by the complexity of the pathology.
Update on Sentinel Lymph Node Methods and Pathology in Breast Cancer
Authors: Zhang-Yin Jules , Mauel Etienne , Talpe Stéphanie
Published: January 2024

Breast cancer stands out as the most commonly diagnosed cancer among women globally. Precise lymph node staging holds critical significance for both predicting outcomes in early-stage disease and formulating effective treatment strategies to control regional disease progression in breast cancer patients. No imaging technique possesses sufficient accuracy to identify lymph node metastases in the early stages (I or II) of primary breast cancer. However, the sentinel node procedure emerges as a valuable approach for identifying metastatic axillary nodes. The sentinel lymph node is the hypothetical first lymph node or group of nodes draining a cancer. In case of established cancerous dissemination, it is postulated that the sentinel lymph nodes are the target organs primarily reached by metastasizing cancer cells from the tumor. The utilization of the sentinel node technique has brought about changes in the assessment of lymph nodes. It involves evaluating the sentinel node during surgery, enabling prompt lymph node dissection when the sentinel node procedure is positive. Additionally, histological ultra-stratification is employed to uncover occult metastases. This review aims to provide an update of this valuable technique, with focus on the practical aspects of the procedure and the different histological protocols of sentinel node evaluation in breast cancer.
Tensorized Discrete Multi-View Spectral Clustering
Authors: Li Qin , Yang Geng , Yun Yu , Lei Yu , You Jane
Published: January 2024

Discrete spectral clustering directly obtains the discrete labels of data, but existing clustering methods assume that the real-valued indicator matrices of different views are identical, which is unreasonable in practical applications. Moreover, they do not effectively exploit the spatial structure and complementary information embedded in views. To overcome this disadvantage, we propose a tensorized discrete multi-view spectral clustering model that integrates spectral embedding and spectral rotation into a unified framework. Specifically, we leverage the weighted tensor nuclear-norm regularizer on the third-order tensor, which consists of the real-valued indicator matrices of views, to exploit the complementary information embedded in the indicator matrices of different views. Furthermore, we present an adaptively weighted scheme that takes into account the relationship between views for clustering. Finally, discrete labels are obtained by spectral rotation. Experiments show the effectiveness of our proposed method.
The Influence of Different Sustainable Substrates on the Nutritional Value of Tenebrio molitor Larvae
Authors: Jankauskienė Agnė , Aleknavičius Dominykas , Kiseliovienė Sandra , Antanaitis Šarūnas , Falkauskas Rimvydas , Šumskienė Marijona , Juknienė Ignė , Kabašinskienė Aistė
Published: January 2024

Every year, over 30% of food production is wasted. However, promoting a sustainable food supply not only fosters economic stability in agriculture and the food industry, but also safeguards precious natural resources and ensures universal food access and safety. Therefore, the aim of the study was to determine how specific growth conditions (utilizing by-products: sprouted potatoes (1), wheat bran (2), brewers’ spent grain (3), and a control sample with agar-agar gels (4)) affect the larvae of yellow mealworms (Tenebrio molitor). This includes their nutritional and energy value, consumer sensory profiling, and technological parameters of processing. The results have indicated that larvae reared on the substrate with wheat bran had the highest energy value, at 708.26 kcal. In larvae, the difference in protein content was not significant when changing the rearing conditions, and ranged between 48.54 and 59.18%. The larvae contained a significant content of fibers, with the highest amount detected in samples with brewers’ spent grain. The data indicate that glucose and arabinose were distinctive to larvae. Our study has also revealed a statistical difference in ash content between larvae and the substrate, with higher levels of nitrogen, copper, and zinc detected in the larvae compared to the substrate. We have found that the salt was naturally occurring in the substrates, with the brewers’ spent grain sample having the highest amount, at 1.83%. However, the control sample yielded the highest ratings, achieving a score of 7.30 for general smell acceptability. These findings emphasize the potential of utilizing various industrial and farm by-products as substrates for mealworms, transforming them into a sustainable and nutrient-rich food source. This contribution adds to the broader discourse on nutritional value and resource efficiency.
The Impact of Various Types of Cooking on the Fate of Hg and Se in Predatory Fish Species
Authors: Ribeiro Mariana , Douis Laurène , Silva José Armando Luísa da , Castanheira Isabel , Leufroy Axelle , Jitaru Petru
Published: January 2024

This study addresses the effect of various cooking approaches on total Hg (HgT) and total Se (SeT) contents in three predatory fish species. For this purpose, samples of swordfish, dogfish, and tuna from regular French (fish) markets were cooked by boiling, steaming, grilling, and frying, respectively. The levels of HgT and SeT in raw and cooked samples were determined by inductively coupled plasma-mass spectrometry. The data showed a significant increase in HgT and SeT levels between raw and cooked samples (33% of the samples for SeT and 67% for HgT) due to the water loss during the cooking. High intra-species variation related to HgT and SeT levels was found. Considering the level of exposure to HgT through fish consumption and taking also into account the possible protective effect of Se (expressed here via the Se/Hg molar ratio), the safest cooking approach corresponds to grilled swordfish, fried tuna, and steamed dogfish, which show Se/Hg molar ratios of (1.0 ± 0.5), (4.3 ± 4.2), and (1.0 ± 0.6), respectively.
In Vitro Release of Glycyrrhiza Glabra Extract by a Gel-Based Microneedle Patch for Psoriasis Treatment
Authors: Khorshidian Ayeh , Sharifi Niloufar , Choupani Kheirabadi Fatemeh , Rezaei Farnoushsadat , Sheikholeslami Seyed Alireza , Ariyannejad Ayda , Esmaeili Javad , Basati Hojat , Barati Aboulfazl
Published: January 2024

Microneedle patches are attractive drug delivery systems that give hope for treating skin disorders. In this study, to first fabricate a chitosan-based low-cost microneedle patch (MNP) using a CO2 laser cutter for in vitro purposes was tried and then the delivery and impact of Glycyrrhiza glabra extract (GgE) on the cell population by this microneedle was evaluated. Microscopic analysis, swelling, penetration, degradation, biocompatibility, and drug delivery were carried out to assess the patch’s performance. DAPI staining and acridine orange (AO) staining were performed to evaluate cell numbers. Based on the results, the MNs were conical and sharp enough (diameter: 400–500 μm, height: 700–900 μm). They showed notable swelling (2 folds) during 5 min and good degradability during 30 min, which can be considered a burst release. The MNP showed no cytotoxicity against fibroblast cell line L929. It also demonstrated good potential for GgE delivery. The results from AO and DAPI staining approved the reduction in the cell population after GgE delivery. To sum up, the fabricated MNP can be a useful recommendation for lab-scale studies. In addition, a GgE-loaded MNP can be a good remedy for skin disorders in which cell proliferation needs to be controlled.
Knowledge, Attitudes, and Practices of Parents in the Use of Antibiotics: A Case Study in a Mexican Indigenous Community
Authors: González-Villoria Ana María , García Quiroz Alma Delia , Osorio Guzmán Edgar Ulises , Suarez-Herrera José Carlos , Abeldaño Zuñiga Roberto Ariel
Published: January 2024

The rise and spread of antibiotic-resistant bacteria have become a global health problem. At the community level, bacterial resistance has been linked to antibiotic misuse practices. These practices are related to social factors such as education level, poverty, ethnicity, and use of traditional medicine. Through a survey, this study aims to analyse the knowledge, attitudes, and practices (KAP) of antimicrobial use, in an indigenous community in the south of Oaxaca, Mexico. It was observed that the population had a low socioeconomic profile, poor access to healthcare services, low academic level, little knowledge of antibiotics, the use of traditional medicine, and proper attitudes and practices regarding antibiotics use. Therefore, social factors are related to bacterial resistance only if they make the population prone to the use of antimicrobials. Lack of medical access and cultural factors drives this population to use ancestral alternatives such traditional medicine to treat conditions that in other contexts could be treated with antibiotics. This is an example of how the population can reduce the consumption of antimicrobials in infections if they have a reliable alternative that improves their symptoms.
Utility of Intermediate Care Units: A Systematic Review Study
Authors: López-Jardón Paula , Martínez-Fernández María Cristina , García-Fernández Rubén , Martín-Vázquez Cristian , Verdeal-Dacal Rodrigo
Published: January 2024

Intermediate care units (IMCUs) have become increasingly important in the care of critical and semi-critical patients, particularly during the COVID-19 pandemic. However, there is still no clear definition of their structural characteristics, specialties, types of patients, and the benefits they provide. The aim of this work is to describe the current state of implementation and operation of IMCUs in hospitals and patient care. To achieve this goal, a systematic review was conducted in the Web of Science, Scopus and CINAHL databases, along with a hand search. The research yielded 419 documents, of which 26 were included in this review after applying inclusion and exclusion criteria. The results were highly diverse and were categorized based on the following topics: material resources, human resources, continuity of care, and patient benefits. Despite the different objectives outlined in the studies, all of them demonstrate the numerous benefits provided by an IMCU, along with the increased relevance of this type of unit in recent years. Therefore, this systematic review highlights the benefits of IMCUs in the care of critical patients, as well as the role of health workers in these units.
Empowering Community Health Workers in Japan: Determinants of Non-Communicable Disease Prevention Competency
Authors: Imamatsu Yuki , Iwata Yuka , Yokoyama Ayuka , Tanaka Yuko , Tadaka Etsuko
Published: January 2024

Background: Community health workers (CHWs), hailing from the general populace, play a pivotal role in fortifying healthcare systems, with a primary focus on mitigating non-communicable diseases (NCDs) and elevating overall life expectancy. To assess the aptitude of CHWs in NCD prevention, we introduced the Community Health Workers Perceptual and Behavioral Competency Scale for preventing non-communicable diseases (COCS-N). This study examines the multifaceted interplay of individual and community factors that influence CHWs’ COCS-N scores. Methods: The research design is a secondary analysis using data from a self-administered questionnaire survey of 6480 CHWs residing in municipalities across Japan, which obtained 3120 valid responses, between September to November 2020. The COCS-N was employed as the dependent variable, while the independent variables were individual-related factors, including years of community health work, health literacy, and community-related factors, such as CHWs’ sense of community. To ascertain the significance of associations between individual and community factors and CHWs’ competency, an analysis of covariance (ANCOVA) was utilized to compare the three groups Q1/Q2/Q3 by low, medium, and high scores on the COCS-N scale. Statistical significance was considered to be indicated by a p-value of less than 0.05. Results: The ANCOVA analysis revealed that three factors were significantly linked to CHWs’ competence. These comprised individual factors: “years of CHWs” (mean ± SD Q1: 6.0 ± 6.0, Q2: 7.8 ± 7.0, Q3: 8.2 ± 7.7, p < 0.001) and “health literacy” (Q1: 27.7 ± 6.6, Q2: 30.4 ± 6.9, Q3: 33.8 ± 7.8, p < 0.001), as well as a community factor: “Sense of community” (Q1: 14.8 ± 3.7, Q2: 16.5 ± 3.5, Q3: 18.2 ± 3.6, p < 0.001). Conclusions: Our finding is that a positive association was derived between COCS-N scores and certain determinants. Notably, “years of CHWs” and “health literacy” in the individual domain, along with the “Sense of community” in the communal context, were firmly established as being significantly associated with CHWs’ competency. Consequently, CHWs need training to increase their “health literacy” and “sense of community”, to acquire high competency in NCD prevention, which will lead to the empowerment of CHWs and maintain their motivation to continue.
The Immediate Effect of Hanging Exercise and Muscle Cylinder Exercise on the Angle of Trunk Rotation in Adolescent Idiopathic Scoliosis
Authors: Akçay Burçin , Çolak Tuğba Kuru , Apti Adnan , Çolak İlker
Published: January 2024

(1) Background: Semi-hanging and muscle cylinder exercises have been defined as scoliosis-specific corrective exercises. The aim of this study was to evaluate the immediate effect of muscle cylinder and semi-hanging exercises on the angle of trunk rotation in patients with adolescent idiopathic scoliosis (AIS). (2) Methods: Twenty-seven patients with AIS with a mean age of 18.6 years were retrospectively analyzed. The angle of trunk rotation (ATR) values were measured before and after performing semi-hanging and standing muscle cylinder exercises. Both exercises were performed for three to five respiratory cycles. The semi-hanging exercise was performed first, followed by the muscle cylinder exercise, in this order, in all participants. For statistical analysis, the Wilcoxon signed-rank test was used to analyze ATR changes after the exercises, and the Kruskal–Wallis test was used to compare ATR changes according to the main curve location. (3) Results: The thoracic, thoracolumbar and lumbar maximum ATR values were significantly increased after the semi-hanging exercise (p < 0.001) and decreased after the muscle cylinder exercise (p < 0.001). The ATR change was greater in the lumbar region than in the thoracic and thoracolumbar regions. (4) Conclusion: The results of this study of a small group of patients emphasized that one of the scoliosis-specific corrective exercises, the standing muscle cylinder exercise, improved ATR, while the other, the semi-hanging exercise, worsened ATR in patients with AIS. It is recommended that each scoliosis-specific corrective exercise be evaluated and redesigned to maximize the three-dimensional corrective effect, considering the biomechanics of the spine and the pathomechanics of scoliosis.
Predicting Operating Income via a Generalized Operating-Leverage Model
Authors: Lambert Sherwood Lane , Krieger Kevin , Mauck Nathan
Published: January 2024

We propose a generalized, practitioner-oriented operating-leverage model for predicting operating income using net sales, cost of sales, depreciation, and SG&A. Prior research links operating income directly to these items; hence, our model includes all aggregate revenues and expenses that comprise operating income. Prior research finds that the cost of sales is “much less” sticky than depreciation and SG&A; hence, we use the cost of sales as a proxy for the total variable costs and depreciation and SG&A as proxies for the sticky fixed costs. We introduce a new adjustment to the textbook operating-leverage model so that the ratio of sales to the cost of sales remains constant for the reference and forecast periods. Inspired by prior research, we adjust depreciation and SG&A for cost stickiness. We find that using our generalized operating-leverage model improves the forecast accuracy of next-quarter and next-year operating income predictions compared to predictions made using textbook operating leverage, which is a special case of our model.
A Review about the Mycoremediation of Soil Impacted by War-like Activities: Challenges and Gaps
Authors: Geris Regina , Malta Marcos , Soares Luar Aguiar , de Souza Neta Lourdes Cardoso , Pereira Natan Silva , Soares Miguel , Reis Vanessa da Silva , Pereira Madson de Godoi
Published: January 2024

(1) Background: The frequency and intensity of war-like activities (war, military training, and shooting ranges) worldwide cause soil pollution by metals, metalloids, explosives, radionuclides, and herbicides. Despite this environmentally worrying scenario, soil decontamination in former war zones almost always involves incineration. Nevertheless, this practice is expensive, and its efficiency is suitable only for organic pollutants. Therefore, treating soils polluted by wars requires efficient and economically viable alternatives. In this sense, this manuscript reviews the status and knowledge gaps of mycoremediation. (2) Methods: The literature review consisted of searches on ScienceDirect and Web of Science for articles (1980 to 2023) on the mycoremediation of soils containing pollutants derived from war-like activities. (3) Results: This review highlighted that mycoremediation has many successful applications for removing all pollutants of war-like activities. However, the mycoremediation of soils in former war zones and those impacted by military training and shooting ranges is still very incipient, with most applications emphasizing explosives. (4) Conclusion: The mycoremediation of soils from conflict zones is an entirely open field of research, and the main challenge is to optimize experimental conditions on a field scale.
Multi-Locus Microsatellite Typing of Colonising and Invasive Aspergillus fumigatus Isolates from Patients Post Lung Transplantation and with Chronic Lung Disease
Authors: Birnie Joshua D. , Ahmed Tanveer , Kidd Sarah E. , Westall Glen P. , Snell Gregory I. , Peleg Anton Y. , Morrissey Catherine Orla
Published: January 2024

Aspergillus fumigatus can cause different clinical manifestations/phenotypes in lung transplant (LTx) recipients and patients with chronic respiratory diseases. It can also precipitate chronic lung allograft dysfunction (CLAD) in LTx recipients. Many host factors have been linked with the severity of A. fumigatus infection, but little is known about the contribution of different A. fumigatus strains to the development of different phenotypes and CLAD. We used multi-locus microsatellite typing (MLMT) to determine if there is a relationship between strain (i.e., genotype) and phenotype in 60 patients post LTx or with chronic respiratory disease across two time periods (1 November 2006–31 March 2009 and 1 November 2015–30 June 2017). The MLMT (STRAf) assay was highly discriminatory (Simpson’s diversity index of 0.9819–0.9942) with no dominant strain detected. No specific genotype–phenotype link was detected, but several clusters and related strains were associated with invasive aspergillosis (IA) and colonisation in the absence of CLAD. Host factors were linked to clinical phenotypes, with prior lymphopenia significantly more common in IA cases as compared with A. fumigatus-colonised patients (12/16 [75%] vs. 13/36 [36.1%]; p = 0.01), and prior Staphylococcus aureus infection was a significant risk factor for the development of IA (odds ratio 13.8; 95% confidence interval [2.01–279.23]). A trend toward a greater incidence of CMV reactivation post-A. fumigatus isolation was observed (0 vs. 5; p = 0.06) in LTx recipients. Further research is required to determine the pathogenicity and immunogenicity of specific A. fumigatus strains.
Geomorphosites as Geotouristic Resources: Assessment of Geomorphological Heritage for Local Development in the Río Lobos Natural Park
Authors: Ruiz-Pedrosa Rosa María , González-Amuchástegui María José , Serrano Enrique
Published: January 2024

Natural protected areas (NPAs) are territorial resources that have received an increasing number of visitors in societies with a high demand for landscapes of high aesthetic and scenic value. Tourism is one of the main activities in NPAs, and within this, geotourism plays an important role, becoming an effective resource in the promotion of natural heritage with repercussions on local and regional economic development. The aim of this work is to analyse geomorphosites’ tourist potential in natural protected areas, focusing on the case of the Río Lobos Natural Park (Castilla-León, Spain) and its geotourism cartography, as well as the proposal of different geotourism routes. To this end, a methodology is applied to the 14 geomorphosites inventoried in the Cañón del Río Lobos, based on a combination of different methods. Its application results in a classification with three thresholds (high, medium and low) for each geomorphosite analysed. In addition, a series of management proposals are included. The validity of this methodology applied for the evaluation of the tourist potential of geomorphosites endorses its application for other natural protected areas.
A Model of the Control Problem of the Thermal Effect of a Laser Beam on a Two-Layer Biomaterial
Authors: Barseghyan Vanya , Solodusha Svetlana
Published: January 2024

We consider a two-layer biological object consisting of layers with different thermophysical characteristics and subjected to laser radiation. Using the method of separation of variables and methods of control theory for finite-dimensional systems, we developed a constructive approach to constructing a control function for the thermal effect of a laser beam on a two-layer biomaterial. Under the controlled thermal influence of a laser beam, the distribution of the temperature state in a two-layer biomaterial transitions from the initial state to the final one during a given time period.
An Energy-Efficient Unrelated Parallel Machine Scheduling Problem with Batch Processing and Time-of-Use Electricity Prices
Authors: Feng Liman , Chen Guo , Zhou Shengchao , Zhou Xiaojun , Jin Mingzhou
Published: January 2024

The extensive consumption of energy in manufacturing has led to a large amount of greenhouse gas emissions that have caused an enormous effect on the environment. Therefore, investigating how to reduce energy consumption in manufacturing is of great significance to cleaner production. This paper considers an energy-conscious unrelated parallel batch processing machine scheduling problem under time-of-use (TOU) electricity prices. Under TOU, electricity prices vary for different periods of a day. This problem is grouping jobs into batches, assigning the batches to machines and allocating time to the batches so as to minimize the total electricity cost. A mixed-integer linear programming model and two groups of heuristics are proposed to solve this problem. The first group of heuristics first forms batches, assigns the batches to machines and finally allocates time to the batches, while the second group of heuristics first assigns jobs to machines, batches the jobs on each machine and finally allocates time to each batch. The computational results show that the SPT-FBLPT-P1 heuristic in the second group can provide high-quality solutions for large-scaled instances in a short time, in which the jobs are assigned to the machines based on the shortest processing time rule, the jobs on each machine are batched following the full-batch longest processing time algorithm, and the time is allocated to each batch following an integer programming approach. The MDEC-FBLPT-P1 heuristic that uses the minimum difference of the power consumption algorithm to assign the jobs also performed well.
Laguerre-Type Bernoulli and Euler Numbers and Related Fractional Polynomials
Authors: Ricci Paolo Emilio , Srivastava Rekha , Caratelli Diego
Published: January 2024

We extended the classical Bernoulli and Euler numbers and polynomials to introduce the Laguerre-type Bernoulli and Euler numbers and related fractional polynomials. The case of fractional Bernoulli and Euler polynomials and numbers has already been considered in a previous paper of which this article is a further generalization. Furthermore, we exploited the Laguerre-type fractional exponentials to define a generalized form of the classical Laplace transform. We show some examples of these generalized mathematical entities, which were derived using the computer algebra system Mathematica© (latest v. 14.0).
Impact of Anthropogenic Activities on Microbial Community Structure in Riverbed Sediments of East Kazakhstan
Authors: Muter Olga , Gudrā Dita , Daumova Gulzhan , Idrisheva Zhanat , Rakhymberdina Marzhan , Tabors Guntis , Dirnēna Baiba , Dobkeviča Linda , Petrova Olga , Apshikur Baitak , Luņģe Megija , Fridmanis Dāvids , Denissov Igor , Bekishev Yerkebulan , Kasparinskis Raimonds , Mukulysova Zarina , Polezhayev Stanislav
Published: January 2024

Heavy metal (HMe) pollution in regions with mining and metallurgy activities is known to be a serious environmental problem worldwide. Hydrological processes contribute to the dissemination of HMes (drainage, precipitation, flow rate). The aim of the present study is to investigate the microbial community structure in ten river sediments sampled in different regions of East Kazakhstan, which are contaminated with HMes. The overall degree of sediment contamination with HMes (Cr, Cu, Zn, Pb, and Cd) was assessed using the pollution index Zc, which ranged from 0.43 to 21.6, with the highest in Ridder City (Zc = 21.6) and Ust-Kamenogorsk City, 0.8 km below the dam of the hydroelectric power station (Zc = 19.6). The tested samples considerably differed in organic matter, total carbon, nitrogen, and phosphorus content, as well as in the abundance of HMe-related functional gene families and antibiotic resistance genes. Metagenomic analysis of benthic microorganisms showed the prevalence of Proteobacteria (88.84–97.61%) and Actinobacteria (1.21–5.98%) at the phylum level in all samples. At the class level, Actinobacteria (21.68–57.48%), Betaproteobacteria (19.38–41.17%), and Alphaproteobacteria (10.0–39.78%) were the most common among the classified reads. To the best of our knowledge, this is the first study on the metagenomic characteristics of benthic microbial communities exposed to chronic HMe pressure in different regions of East Kazakhstan.
Synthesis and Characterization of Mesoporous Silica Nanoparticles Loaded with P-Cymene against Rice Bacterial Blight
Authors: Li Chaonan , Mo Yalan , Jiao Luying , Liu Yiping , Li Xiaogang
Published: January 2024

Mesoporous silica nanoparticles (MSNs) can be used as carrier materials for the controlled release of pesticides while reducing their negative environmental impact. In this study, we screened an active ingredient, p-cymene (PC), with an excellent inhibitory effect on rice bacterial blight. Subsequently, the PC was successfully loaded onto MSNs via physisorption (PC@MSNs). PC@MSNs, characterized by a regular spherical shape, smooth surface, and an MSN average size of 262.9 nm, achieved an 8.6% drug loading capacity. The release kinetics of the PC from the PC@MSNs demonstrated a sustained release (288 h) pattern influenced by drug diffusion. The efficacy of the PC@MSNs against Xanthomonas oryzae pv. Oryzae paralleled those of PC. Acute toxicity assays revealed that the PC@MSNs were less toxic to aquatic life (LC50 = 257.867 mg/L) and that the formulation showed no adverse effects on rice seedling growth. In summary, these results suggest that PC@MSNs can broaden PC’s scope of application in managing rice diseases.
Environmental Protection through Aerobic Granular Sludge Process
Authors: Liu Yong-Qiang
Published: January 2024

Aerobic granular sludge (AGS) represents a significant advancement in wastewater treatment technology [...]
Development of an Experimental Dead-End Microfiltration Layout and Process Repeatability Analysis
Authors: Bombek Gorazd , Kevorkijan Luka , Hrovat Grega , Kuzman Drago , Kapun Aleks , Ravnik Jure , Hriberšek Matjaž , Hribernik Aleš
Published: January 2024

Microfiltration is an important process in the pharmaceutical industry. Filter selection and validation is a time-consuming and expensive process. Quality by design approach is important for product safety. The article covers the instrumentalization and process control of a laboratory-scale dead-end microfiltration layout. The layout is a downscale model of the actual production line, and the goal is filter validation and analysis of process parameters, which may influence filter operation. Filter size, fluid pressure, valve plunger speed, and timing issues were considered. The focus is on the identification of the most influential process parameters and their influence on the repeatability of pressure oscillations caused by valve opening. The goal was to find the worst-case scenario regarding pressure oscillations and, consequently, filter energy intake. The layout was designed as compact as possible to reduce pressure losses between the filter and valve. Valve-induced pressure oscillations proved to be prevailing over the water hammer effect. Several filters in sizes between 3.5 cm2 and 6900 cm2 were tested, and some recommendations were suggested for the reduction of energy intake of the filter and to improve the repeatability of the process.