bluuebunny/crossref_metadata_2025 huggingface dataset:
Modelling the Development Dynamics of Small and Medium-Sized Enterprises in Russia
Authors: Chunikhin Sergey A.
Published: March 2020

The paper explores the factors in the development of small and medium-sized entrepreneurship (SME) in Russia over the past 13 years. The purpose of the article is to identify the patterns and current trends in the dynamics of the number of SMEs. The present study carries out correlation and regression analysis of the factors using the statistical data for 2006–2018. The number of the employed and the average nominal wage are the factors that exert a positive effect on the number of small enterprises, whereas tax burden, the weighted average rate for short-term loans and the inflation rate have a negative impact. The research results allowed forecasting the development dynamics of SMEs for 2020–2024. Providing that Russia follows the basic scenario of the socio-economic development and the existing trends persist, the total number of SMEs is expected to grow to 3,636 thousand (1.37 times) by 2024.
Entrepreneurship in the third age: data from Russia
Authors: Pinkovetskaia I. S. , Nuretdinova Y. V. , Navasardyan A. A.
Published: March 2020

The purpose of the study was to analyze the features of early entrepreneurial activity in the third age, to assess the dynamics of its change in recent years in Russia and the projected values for the future. The study examined the advantages and disadvantages of early entrepreneurship in the age group, estimated its levels for the period from 2013 to 2018, compared business activity in Russia and a number of large economically developed countries, and proposed a forecast of the potential number of start-up entrepreneurs, taking into account current trends. The results of surveys conducted during the Global monitoring of entrepreneurship and the corresponding national report on Russia, as well as official information from the Federal state statistics service, reflecting the population size by age groups and demographic forecast, were used as initial data for the study.
Evaluation of indicators of entrepreneurial potential in 2018
Authors: Pinkovetskaia I. S. , Kostina T. I. , Berezina N. V.
Published: March 2020

Entrepreneurial potential of the population is largely determined by how adults evaluate their intentions in terms of creating their own business. The purpose of the study was to assess the existing indicators in 2018 that characterize the potential entrepreneurial activity of the population in different countries. The self-assessment of people on such factors as their ability and ability to create their own businesses, entrepreneurial purposes, fear of failure in this activity, as well as the presence of familiar entrepreneurs were considered as the estimated indicators. The study used information from the Global entrepreneurship monitor for 2018 for 48 countries. Three hypotheses were tested using mathematical models representing the density functions of the normal distribution. Five indicators of entrepreneurial potential were used to determine their average values for the countries under consideration. Countries with high and low values of indicators were identified. A comparative analysis of the entrepreneurial potential in Russia and foreign countries is carried out.
Cargo cult agile: Use of information technology by senior executives for decision making activities
Authors: Sajjad Muhammad , . Orangzab , Chani Muhammad Irfan , Tahir Muhammad Sohail
Published: March 2020

Cargo cult agile is a metaphorical notion for senior executives (SEs’) who have latest and costly information tools at workplace but their use for decision making is very limited. The study initiated to measure the use of information technology (IT) by senior executives for decision making activities. For this very purpose, territory of Islamabad, Pakistan were chosen for survey. Target population were top ranked officers or executives from the public organizations. Access to these executives were a big challenge, so the snowball sampling was the only technique which were employed in this study.  A semi structured interview technique was used for data collection. This semi structured interview was divided into four portions. In first portion, simple and direct questions were asked about the routine tasks performed by senior executives while using their personal computers or laptops. Second portion consisted of questions related to hardware knowledge while the third portion have the questions about use of web, emails or blogs. The fourth and utmost important portion of this semi structured interview consisted of questions related to decision making activities. All responses were recorded on piece of papers in hard form and later transformed into percentages. It was found that most of the senior executives use their personal computers or laptops for drafting or for instant communication using internet. The real essence or tasks of these executives are impugned in decision making activities as per the title or resources they availed. But unfortunately, they have been stuck in minion jobs of IT which can be easily performed by their subordinates. The study highlighted and identified the cult of this modern era and urged the senior executives to effectively utilize the IT for decision making activities.
Legal issues of protection of agricultural land in Ukraine at the present stage
Authors: Lisova Tetiana , Sharapova Svitlana
Published: March 2020

Excessive anthropogenic pressure on land resources in Ukraine leads to a deterioration of their quality, and consequently they lose their potential. Human impact on the change of land quality can be direct (by involving land lots in use, carrying out economic activities) and indirect (as a result of such activity, enhancing the natural degradation of soils). The tendency of deterioration of the state of land resources requires the subordination of land relations to the main goal – to ensure comprehensive protection of this major national wealth of Ukraine.

Legal support for the protection of agricultural land is considered as a single complex of interdependent elements: legal standards for the protection of land, soil, agricultural landscapes, and the mechanism for their implementation – legally significant measures: economic, organizational, scientific and technical. At the same time, it was concluded that the system of legal regulation of the use of agricultural land is not sufficiently saturated with mechanisms for regulating agricultural activity.
Information society: the interaction of tradition and innovation in communicative processes
Authors: Bytiak Yuriy P. , Danilyan Oleg G. , Dzeban Alexander P. , Kalinovsky Yury Y. , Chalapko Volodymyr V.
Published: March 2020

Scientific novelty of work is in revealing the key aspects of understanding the nature and characteristics of contemporary processes of communication at various levels of socially organized matter, in identifying their most significant features in conditions of the actual information society. The article expresses the view that in modern society, reality is manifested in the form of “normal accidens”, and in this context some of the most illustrative trends of modern social development, that are manifested in various aspects of human activity are highlighted that are the “normal accidents”. It is substantiated that modern network communications are characterized by non-linearity, absence of a core and hierarchy, which affects the dynamics of society. Conclusions. New forms of communication are multidirectional and ambiguous: on the one hand, they are a continuation and a new measurement of the traditionally established forms of public communication and, on the other hand, they are socio-cultural innovations capable of a new influence on the quality of life of an individual, functionality and dynamics of society and its institutions development.
Requisitos del procedimiento de certificación de personal en la empresa de la industria de la aviación
Authors: Prosvirina Natalya Viktorovna
Published: March 2020

El propósito de este estudio es analizar e identificar las características del sistema de certificación de personal en la empresa de la industria de la aviación, que es uno de los sectores principales de alta tecnología y alta tecnología del complejo industrial de defensa ruso. Las cuestiones relacionadas con la certificación de personal en empresas de industrias de alta tecnología son actualmente particularmente relevantes. Dado que la certificación de los empleados es la función más importante del servicio de personal, que es un examen periódico de la idoneidad profesional y el cumplimiento del puesto que ocupa un empleado de la organización. Permite a los empleados recibir comentarios, una evaluación de su trabajo, motivar a sus colegas a trabajar de manera efectiva; identificar el potencial de los empleados, justificar decisiones sobre la rotación del personal, evaluar la efectividad de la capacitación de los empleados, determinar áreas de trabajo para el desarrollo y desarrollo del personal; crear un grupo de talentos para ascender a puestos más altos. Se necesita la certificación de los empleados de la empresa de la industria de la aviación para evaluar la composición de calidad del personal de la organización, identificar la carga de cada miembro del equipo, identificar problemas y direcciones para mejorar el estilo y los métodos de gestión del colectivo laboral. Para lograr este objetivo, se resolvieron las siguientes tareas: se estudiaron los objetivos de certificación de los empleados de la empresa de la industria de la aviación; se muestran los criterios para la certificación del personal, los métodos y las etapas de su implementación; se analiza la efectividad de la certificación y la racionalización de los lugares de trabajo de la empresa de la industria de la aviación; Se consideran los principales errores de gestión durante la certificación del personal de la empresa. Para esto, se utilizaron métodos de investigación teórica y empírica.
Historical and pedagogical experience of the formation of the educational system of the Primorsky special school
Authors: Tikhiy Konstantin Teodorovich , Shurukhina Tatiana Nikolaevna , Belov Alexander Nikitovich , Tarasenko Vladimir Nikolaevich , Anisimov Aleksandr Leonidovich
Published: March 2020

The article presents the results of historical and pedagogical analysis of the educational system of the Primorsky special school. The purpose of this work is to analyze the experience of the formation and development of the adaptation system of juvenile delinquents in a special school. In the late 1960s and the first half of the 1970s, this experience was completely new in the educational system, since there were no such types of educational institutions in Soviet practice, so there was a need to find new methods to achieve educational, educational and rehabilitation tasks in work with difficult teens. This article analyzes the emerging techniques and methods of educational and social and adaptation activities of adolescents in a special school in the 70s of the twentieth century. Results. The experience of the formation of the educational system of the Primorsky special school is described, the mechanisms of the successful functioning of special schools are shown, the specifics of the relationship between teachers, educators and pupils are highlighted.
Certain aspects of personal data protection in the social network: european experience and legislative regulation in Ukraine
Authors: Davydova Iryna , Bernaz-Lukavetska Olena , Reznichenko Semen
Published: March 2020

The purpose of this study is to examine some aspects of personal data protection in the social network, a comparative analysis of the protection of personal data in the social network under Ukrainian and European legislation, namely the General Data Protection Regulation of the European Union. The methods used in this work are: dialectical, comparative-legal, formal-logical, analysis and dogmatic interpretation. Each of these methods was used in the study to understand and qualitatively explain to the audience categories the individual aspects of personal data protection on the social network. This article reveals the notion of: personal data in the social network, the features of their collection, storage and protection in accordance with European legislation and the development of proposals aimed at improving these processes in Ukraine. The research also addresses the following issues: Features of managing consent to the processing of personal data that have already been obtained; who can act as an "operator" under EU law and what actions he can take; who can act as "controller" and what functions it performs. The article concludes that there is an urgent need to streamline Ukrainian domestic legislation in line with EU law, which should result in a new law on personal data protection that complies with GDPR norms. As a result, a new law on personal data protection may soon emerge in Ukraine, replacing the outdated Law of Ukraine “On Personal Data Protection” of 01.06.2010, which is a “mirror” of the repealed Directive 95/46/EC of the European Parliament and of the Council.
Evaluation of fishing industry clusterization in the russian far east within the context of integration with Asian-Pacific markets
Authors: Saltykov Maxim Alexandrovich , Stetsyuk Victor Victorovich , Pravikov Oleg Vladimirovich
Published: March 2020

The study’s aim is to assess the potential and processes of formation of sectoral clusters in the Far Eastern regions fishing industry.
The paper suggests the strategy for forming the fishing industry clusters in the Russian Far East, analyzes trends, taking place in the fishing industry, from the perspective of its clusterization, interprets locatization and density ratios of capture fisheries and fish-farming businesses in the Far Eastern territories.
The research first describes methods used to evaluate localization and geographical density of fishing-industry companies in the Far Eastern regions, and offers methodological recommendations for investigating fishing industry clusters. The second stage outlines trends of the industry such as increasing harvest level, changing proportion of capture fisheries and fish breeding, growing export, emerging exporting clusters, forming fishing industry associations. The third stage analyzes density ratios and specialization of fishing and fish-farming businesses by regions, compares the calculated ratios’ values to other Russian regions’ ones. On the basis of integral ratio we estimate the potential for clusterization of the fishing industry in Russian regions as well as on the territories of the Far Eastern Federal District.
The research comes to conclusion that a set of state support measures and effective investment projects, concerned with the fishing industry cluster, can produce an additional synergetic effect for the whole gross regional product.
Foreign experience of administrative and legal support of citizens' rights by prosecutor's offices and possibilities of its use in Ukraine
Authors: Yevdokimenko Svitlana Viktorivna , Naumova Anna Oleksandrivna , Yakymchuk SvitlanaOleksiivna , Povydysh Vladyslav Volodymyrovych
Published: March 2020

The purpose of the article is to substantiate, on the basis of the analysis of the legislation of France, Italy, Germany, Great Britain and the USA, the ways of improving the legislation of Ukraine in the sphere of ensuring the rights of citizens by the prosecuting authorities.
During the writing of the article, such methods as comparative-legal, system-structural, logical-normative were used.
The relevance of the article is due to the fact that the optimization of the activity of the prosecution bodies is impossible without taking into account foreign experience. This issue is of particular importance in the field of ensuring human rights and freedoms by the prosecuting authorities. Concidering that fact, the legislation of France, Italy, Germany, the United Kingdom and the United States has been analyzed, which made it possible to formulate certain ways of improving national legislation on the protection of citizens' rights by prosecuting authorities. It has been justified to improve the administrative status of the prosecution bodies, to review its functions, the requirements for the level of training and to legislate a clear mechanism for the implementation of functions. According to the results of the study, the authors have identified possible ways of using the positive foreign experience of administrative and legal support of citizens' rights by prosecuting authorities.
Involuntary termination of private property rights under the civil legislation of Ukraine
Authors: Mykhailov Oleksandr , Hryb Anna , Riaboshapchenko Anastasiia
Published: March 2020

The article investigates theoretical and practical problems of civil regulation of involuntary termination of private property rights. Private ownership is one of the essential human rights. That is why it is extremely important to provide its appropriate protection. It is especially important in terms of current Ukrainian realities in the context of continuous hostilities, the temporary occupation of part of the country's territory, rapid economic reforms aimed at bringing the Ukrainian economy closer to the standards of the European Union. The involuntary termination of private property right should be an exception used in very rare cases, established by law. Considering this, the article analyzes established by Ukrainian legislation cases of involuntary termination of private ownership from the point of view of human rights protection. Some imperfections in the legal regulation of involuntary termination of private property are revealed and ways of improvement of the current state are suggested. It is concluded that involuntary termination of private ownership takes place in a limited number of cases, but it does not directly follow from Art. 346 of the Civil Code of Ukraine. It was offered to supply Art. 346 of the Civil Code of Ukraine with the provision that ownership shall be terminated by compulsory order only on the grounds and in the manner provided by the Civil Code and the Laws of Ukraine.
Agricultural Cooperation in The Kyrgyz Republic: Potential, Problems and Prospects
Authors: Maksimov Anatoly А. , Ten Anatoly D.
Published: March 2020

The article has been written in order to disclose the development potential of agricultural cooperation in the Kyrgyz Republic in the conditions of its integration into the unified food market of Eurasian Economic Union member states. Cooperation is considered an efficient economic mechanism of integration of small agricultural producers into national and global food value chains. Upon examination of works revealing the potential of cooperation in the development of value chains, analysis of the agrarian structure and evaluation of the potential held by member states for cooperation, the authors of the article have proposed measures for comprehensive development of agricultural cooperation in the Kyrgyz Republic. The article is based on the materials by international organizations, the National Committee of Statistics of the Kyrgyz Republic, the Eurasian Economic Commission and results of research conducted by separate authors. The article’s materials can be used to generalize the international practice of studying the role of cooperation in the development of food value chains and to improve institutional conditions and government policy of supporting cooperation in the Kyrgyz Republic. They are also of interest for a broad group of researchers in the field of agricultural cooperation.
NT-PROBNP AND THE CUT-OFF VALUE IN CARDIOVASCULAR DISEASES
Authors: Hoang Anh Tien , Huynh Van Minh , Hoang Khanh , Tran Huu Dang , Tran Viet An
Published: March 2020

NT-ProBNP is a high value cardiac biomarker and widely applies in many cardiovascular diseases. The evaluation of concentration of NT-ProBNP needs the concern about age, gender, obesity and especially we need each cut-off point for each cause of cardiovascular disease in evaluation and clinical application. Because NT-ProBNP is a new cardiac marker and has been researched in 5 recent years, the cut-off of NT-ProBNP is still being studied for the clinical application in cardiovascular diseases. Only the cut-off of NT-ProBNP in diagnosis heart failure was guided by European Society of Cardiology. The meaning of introduce cut-off value of value plays an role as pilot study for the other relate study and brings the NT-ProBNP closely approach to clinical application.
STUDY ON EFFICACY OF QUADRUPLE THERAPY RACM IN PATIENTS WITH HP- POSITIVE GASTRIC ULCER
Authors: Vinh Khanh , Pham Ngoc Doanh , Tran Van Huy
Published: March 2020

Objectives: Gastric ulcer is a chronis disease with a lot of dangerous complications and H. pylori is a major cause of gastric ulcer. Eradicating H. pylori helps reducing ulcer relapse and preventing cancer. The aim of study: to evaluate the rate of H. pylori infection in gastric ulcer and efficacy of quadruple therapy RACM for 5 days in patients with gastric ulcer with H. pylori positive. Materials and methods: Total 98 patients with gastric ulcer have been performed the endoscopy and CLO-Test, treated with quadruple therapy RACM for 5 days and evaluate efficacy 4 weeks after ending treatment. Results: The rate of H. pylori in gastric ulcer is 82.65%. The rate of H. pylori eradication is 88.71%. The effect of reducing pain of therapy is 90.32%; and the rate of reducing pain: 96.37% in successfully H. pylori-eradicated group and in the other group 42.85% (p < 0.05). The effect of healing ulcer of therapy is 77.41%; and the rate of healing gastric ulcer: 83.63% in successfully H. pylori-eradicated group and in the other group 28.57% (p < 0.05). The adverse effects of therapy included tiredness: 11.29%, lose appetite: 8.06% and diarrhea: 6.45%. Conclutions: Quadruple therapy RACM for 5 days showed an effective, safe and simple regime for eradicating H. pylori and should be considered to apply as the first lines treatment for H. pylori.
RELATED FACTORS TO RELAPSE IN DEPRESSED PATIENTS AFTER COGNITIVE BEHAVIOURAL THERAPY DURING ONE YEAR PROSPECTIVE FOLLOW-UP
Authors: Tran Nhu Minh Hang , Nguyen Huu Cat , Nguyen Dang Doanh , Ngo Van Luong , Nguyen Vu Hoang , Ho Ngoc Bich
Published: March 2020

Objectives: To determine factors impact on the relapse in depressed patients treated with Cognitive Behavioral Therapy (CBT) during one year follow-up. Materials and Methods: 80 depressed patients divided into two groups, group 1: included 40 patients treated with CBT; group 2: 40 patients on amitriptyline. Non-randomized controlled clinical trial, opened, longiditual and prospective research. Results and Conclusions: relapse rate after CBT during 1 year follow-up is 10% (compared to 25% in control group), related factors to relapse rate in depression after CBT are age and education. Shared predictors between 2 groups are severity and recurrence of depression. Key words: Depression, relapse, Cognitive Behavioral Therapy (CBT)
STUDY ON HOSPITAL INFECTION AND RELATED FACTORS IN PHU YEN PROVINCIAL HOSPITAL IN 2011
Authors:   Hieu Vinh Pham, Dinh Binh Tran
Published: March 2020

Background: Data on hospital infection and related factors are really necessary to have a strategy to reduce hospital infection. Aim: assessing the hospital infection situation in Phu Yen hospital. Method: cross study on the situation of hospital infection in Phu Yen province hospital in 2011. Results and conclusion: The prevalence rate of hospital infection is 5.6%, in which male patients accounted for 57.1% and female patients are 42.9%, in which wound infections are 28.6%, respiratory tract infections are 25,0%, blood infections is 21.4%, infected burns are 10.7%, skin and soft tissue infections 7,1%, neonatal infections and urinary tract infections are 3,6%. Hospital infections related to the time in hospital. The patients that are hospital infections stay in hospital longer. Hospital infection rates is highest in infants that was 12.5%, followed by the 1-15 age group that was 7.9% and group above 60 years was 7.0%. The departments have hospital infection in high rate are emergency (58.8%), surgical trauma, surgical burns and neurological surgery are 13.3%, 8.0% of patients in general surgery department are hospital infections, that was 5.3% in medical services, 4.5% in neonatal department, 1.5% in obstetrics and 1.2% in general internal department.
ARRAY CGH AND ITS APPLICATIONS IN PRENTAL DIAGNOSIS
Authors: Nguyen Viet Nhan , Ha Thi Minh Thi , Nguyen Vu Quoc Huy
Published: March 2020

In prenatal diagnosis, array CGH has several advantages more than traditional chromosomal analysis. It can detect all of aneuploidies, deletions, duplications and unbalanced structural rearrangements of chromosomes with higher resolution, avoidance of culturing amniocytes or chorionic villi, automation, and faster turnaround times. But array CGH has high cost, inability to detect balanced inversions or translocations as well as polyploidy and mosaicism below 20%. Array CGH can identify marker chromosomes and copy number variants (CNVs) of chromosomes but many of them have uncertain clinical significance. So that in prenatal diagnosis array CGH is indicated in the following cases : (1) abnormal fetal ultrasound findings; (2) suspected chromosome imbalances; (3) had children with abnormal chromosomes (4) parents with chromosome balances; (5) advanced maternal age.
STUDY ON CLINICAL AND ENDOSCOPIC FEATURES OF ADENOIDITIS AND RESULT OF ADENOIDECTOMY AT BUON MA THUOT HOSPITAL
Authors: Vo Nguyen Hoang Khoi , Nguyen Thanh Nam , Dang Thanh
Published: March 2020

Objective: Thí study aims to reseach the clinical and endoscopic features of adenoiditis and the efficacy of adenoidectomy with curette of La Force by local anesthesia. Material and method: To study on 35 children sufferring from adenoiditis, adenoidectomied with curette of La Force by local anesthesia, reviewed after 1 month at Buon Ma Thuot Hospital; with prospective descriptive method and having clinical intervention. Results: Mean of age was 8.1 ± 3.0 year old (2-15 years old). The most frequent preoperative clinical symptoms were nasal obstruction 94.3%, rhinorrhea 85.7%, sleep snoring 65.7%, sweating during sleep 62.9%. The postoperative clinical symptomps remarkably reduced compared with those before operating with rates respectively: nasal obstruction (94.3%-5.7%), rhinorrhea (85.7%-8.6%), sleep snoring (65.7%-14.3%), sweating during sleep (62.9%-20%). Preoperative endoscopic evaluation of hypertrophic degree of adenoids: degree I was 2.9%; degree II was 20%; degree III was 40%; degree IV was 37.1%. The change in hypertrophic degree of adenoids by endoscopic review at 1 month postoperatively: absence of adenoids 28.6%, adenoids being smaller than before operating 68.5%; adenoids having the same volume as before operating 2.9%. Conclusions: After adenoidectomy, the clinical symptomps of adenoiditis remarkably reduced; and by endoscopic review, absence of adenoids 28.6%, adenoids being smaller than before operating 68.5%.
ANTIBIOTICS RESISTANCE AND OUTCOMES OF SEPSIS IN HUE CENTRAL HOSPITAL FROM 2009 TO 2010
Authors: Nguyen Thi Phuong Thao , Tran Xuan Chuong
Published: March 2020

Objective: Sepsis is a very important infection. Studying the antibiotic resistance helps doctors to make the right choice for treatment of infections and reduce mortality. Materials and methods: 60 patients diagnosed as sepsis treated at Hue Central hospital, since Jan 2009 to June 2010. Retrospective study. Results: The most isolated agents are E. coli (40% patients), K. pneumoniae (16.7%) and Streptococcus suis (18.3%). Most of agents sensitive to ceftriaxon, ciprofloxacin và gentamicin. 100% sensitive to imipenem. All agents, except S. suis, are resistant to ampicillin. Agents resistant to ceftriaxon, ciprofloxacin and gentamicin have very high mortality (E. coli: 87.5% vs. 43.7%. S. suis : 66.7% vs. 25%). Conclusions: The most isolated agents are E. coli, K. pneumoniae and S. suis. Most of agents sensitive to ceftriaxon, ciprofloxacin và gentamicin. All agents, except S. suis, are resistant to ampicillin. Agents resistant to ceftriaxon, ciprofloxacin and gentamicin have very high mortality.
STUDY ON SLEEP APNEA SYNDROME IN THE PATIENTS WITH CARDIOVASCULAR RISK
Authors: Hoang Anh Tien , Nguyen Huu Duc , Tran Thi Doan , Vo Duc Toan
Published: March 2020

Background: Sleep apnea syndrome is the disease of ceasing the breath when sleeping. The incidence was 5% in the population, more often in female than male. More than 50% of SAS patients have hypertension, diabetes mellitus, coronary syndrome or even sudden death. In Viet Nam there were still a few studies about SAS. Objective: To evaluate the prevalence of cardiovascular risk in SAS patients. Also the correlation between AHI and BMI, SBP, DBP, fasting glucose, Cholesterol, Triglyceride, LDL-C, HDL-C. Materials and Methods: Clinical data of 30 SAS patients admitted to hospital were analysed and compared to 30 well-healthy person, without cardiovascular risk. We evaluate the incidence of cardiovascular risk in the SAS patients. We also find the correlations between AHI and age, BMI, systolic blood pressure, diasystolic blood pressure, fasting glucose, Cholesterol, Triglyceride, LDL-C, HDL-C. Results: 1. The prevalence of cardiovascular risk in SAS patients: lipid disorder 27.59%, hypertension 18.97%, obesity 20.69%, smoking 13.79%, sedentary lifestyle 8.62%, diabetis mellitus 10,34%. 2. There were some positive correlations between AHI and systolic blood pressure r=0.37, p<0.05, p<0.05; Cholesterol r=0.32, p<0.05; BMI r=0.41, p<0.05. Conclusion: Basing on the correlation, cardiovascular risk should be concerned in SAS.
STUDY OF DISTURBANCES OF PHOSPHATE AND PARATHYROID HORMON IN THE ELDERLY CHRONIC HEMODIALYSIS PATIENTS
Authors: Nguyen Bach , Nguyen Thi Le , Vu Dinh Hung
Published: March 2020

Objectives:
1. To identify the prevalence of the elderly chronic hemodialysis patients with dysturbances of Phosphate and PTH.
2. To compare the clinical manifestations and complications of the patients with hyperparathyroidism versus the patients with non-hyperparathyroidism.
3. To compare dysturbances P, PTH in patients dialyzed by high – flux dialyzer versus low-flux.
Materials and method:
Patients: 53 elderly chronic hemodialysis patients in department of Nephrology and Dialysis, Thong Nhat Hospital. The period of study was Sept 2009 to Sept 2010. The criteria inclusion was patients over 60 years of old, chronic hemodialysis more than 6 months, followed strictly medical treatment of hyperparathyroidism and followed closely prescriptions of hemodialysis.
Method: prospective and cross-sectional study. Statistical analysis: SPSS 13.0.
Results: The prevalence of elderly chronic hemodialysis with serum phosphate in normal range, mild, moderate and severe increase was 20.8%; 15.1%; 28.3% and 35.8% respectively. The prevalence of those with serum PTH in normal range and hyperparathyroidism was 13.4% and 26.4% respectively. Systolic and diastolic blood pressure in patients with hyperparathyroidism vs non hyperparathyroidism were 144.64±12.32 vs 142.82±15.89 (p>0.05) and 76.07±6.56 vs 76.67±5.77 (p>0.05). The prevalence of those with uremia itching in hyperparathyroidism group vs non hyperparathyroidism was 52.86% vs 38.46% (p>0.05). Hb (g/dl) in patients with hyperparathyroidism vs non hyperparathyroidism was 10.76±2.93 vs 10.89±1.28 (p>0.05). Total cholesterol and triglyceride (mmol/L) in those with hyperparathyroidism vs non hyperparathyroidism were 4.86±0.89 vs 4.78±1.00 (p>0.05) and 2.11±0.91 vs 2.08±1.31 (p>0.05). The prevalence of hyperparathyroiddism in patients dialysed by high-flux dialyzer was 10% vs 36.36% in those dialysed by low-flux dialyzer (p<0.05).
Conclusions: The prevalence of the elderly chronic hemodialysis patients with dysturbances of Phosphate and PTH was 79.2% and 86.8% respectivelly. In those, 26.4% patients diagnosed hyperparathyroidism (PTH pre HD ≥ 250pg/ml). The differences of clinical manifestations such as blood pressure, itching, anemia and lipid disorders in patients with hyperparathyroidism versus non – hyperparathyroidism were not recorded. The study also shows that lower rate of hyperparathyroidism in the patients dialysed by high-flux dialyzer versus in those dialyzed by low – flux dialyzer.
Key words: chronic hemodialysis; parathyroidism.
AFFECTING MECHANISMS AND EFFECTS OF ENDOCRINE DISRUPTOR PESTICIDES
Authors: Nguyen Ba Tiep , Bui Ngan Tam
Published: March 2020

Endocrine disrupting chemicals are compounds that alter the functioning of endocrine system and subsequently affect on different growth and development stages of human and animals. Endocrine disruptors including pesticides have gained a global attention in various fields like environment toxicology, reproduction, food safety and cancer. This article reviews affecting mechanisms of endocrine disruptors including (1) Interfering steroid hormone synthesis, release, transport and metabolism (2) Effecting via hormone receptors, (3) Effecting the action of thyroid hormones, and (4) affecting on central nervous system. Adverse health effects of pesticides via endocrine disruption pathways and recent discoveries in endocrine disruption mechanisms of common pesticides are also be discussed. The information is necessary for the development of safe and sustainable agricultural systems and public health protection in Vietnam.
Key words: endocrine disruptors, affecting mechanisms, pesticides, public health
TWO POLYOXYGENATED STEROIDS FROM SOFT CORAL SINULARIA CRUCIATA
Authors: Vo Quoc Hung , Nguyen Thi Hoai
Published: March 2020

Background: Marine organisms are rich sources of complicated and various secondary metabolites which have a lager number of valuable bioactivities. Among those, although soft corals are potential materials, they have not been deeply investigated yet. This is an ongoing research to determine the chemical constituents of Vietnamese octocorals Sinularia cruciata. Materials and method: The whole bodies of soft coral Sinularia cruciata collected from Con Co, Quang Tri province. Pure compounds were isolated by using column chromatography normal phase and inverse phase, preparative thin layer chromatography, thin layer chromatography and Shephadex LH-20. Structures of them were determined by spectral data of nuclear magnetic resonance (NMR), electrospray ionization mass spectrometry (ESI-MS). Results & Conclusion: Structures of 2 polyoxygenated steroids were identified: (1) ergosta-3β,5α,6β,11α-tetraol (sarcoaldesterol B) and (2) ergosta-1β,3β,5α,6β-tetraol. Till now, there are no reports about biological effects of these compounds. However, this steroidal group has shown many of precious bioactivities, especially anti-cancer. Key words Sinularia cruciata, sarcoaldesterol B, polyoxygenated steroid, soft coral, cancer.
Key words: Sinularia cruciata, sarcoaldesterol B, polyoxygenated steroid, soft coral, cancer
STUDYING OF KNOWLEDGES, ATTITUDES AND PRACTICES (KAP) TOWARD HIV PREVENTION IN MSM IN KHANH HOA PROVINCE 2010
Authors: Ton That Toan , Tran Xuan Chuong
Published: March 2020

Objectives: Man who have sex with man (MSM) group is a high risk group of HIV infection. There are very rare studies about HIV infection in this group. Aims: Study knowledge, attitudes and practices (KAP) toward HIV prevention in MSM in Khanh Hoa province in 2010. Methods: A cross-sectional study among MSM over 16 years aged living in Khanh Hoa in which data were collected from June 2010 to June 2011. Results: Knowledge: Most of MSM have good knowledge about the ways of HIV transmission in which 47.5% have right answers to 14-15 questions about HIV prevention. Attitudes: 98.5% MSM are ready to do voluntary tests for HIV. 61.5% MSM did not discuss to male partners about HIV or STDs. Practices: 99.1% have used condom but 67.5% did not use condoms in the last contact with female partners. Only 19.6% MSM have received consultations about HIV. Conclusions: Most of MSM have good knowledge about the ways of HIV transmission. 98.5% MSM are ready to do voluntary tests for HIV. 99.1% have used condom. Only 19.6% MSM have received consultations about HIV.
STUDY ON THE RELATION BETWEEN CARCINO-EMBRYONIC ANTIGEN LEVEL AND THE CLINICOPATHOLOGIC FEATURES IN COLORECTAL CARCINOMA
Authors: Dang Cong Thuan , Nguyen Duy Nam Anh
Published: March 2020

Background: We examined the clinicopathologic features and carcinoembryonic antigen (CEA) levels of the colorectal carcinoma patients at Hue University Hospital and Hue Central Hospital. The aim of this study was to evaluate the relation between the pre-operative CEA levels from the post-operative CEA level and the clinicopathologic features in colorectal carcinomas. Materials and methods: From May 2011 to April 2012, samples were collected from 87 colorectal carcinoma patients. The pre-operative and post-operative samples from peripheral blood of the patients were collected to quantity of CEA level by sandwich principle. Results: Most patients were among the age of ≥70; 36.8% of cases. The medium age at presentation was 61.2±15,2. 36.8% (n=32) of the carcinomas were located in rectum and 19.5% in sigmoid colon. The great majority of cases were non-mucinous adenocarcinoma (90.8%). 48,1% of cases with pre-operative CEA level were higher normal level. The medium level of pre-operative CEA was 11.2±16.8 ng/l. Dukes B, C and D classification were 85.1%; 5.7% and 9.2% of cases, respectively. Compared with the pre-operative CEA level, post-operative CEA level was reduced (r = 0.604; p = 0.002). Conclusions: We found that there was a significant relation between pre-operative CEA level from post-operative CEA level (p<0.05), tumor location (p<0.05) and Dukes classification (p<0.05).
Key words: CEA, colorectal carcinoma, clinicopathology
UPDATE ON TREATMENT OF TYPE 2 DIABETES
Authors: Nguyen Thi Nhan
Published: March 2020

80% patients with type 2 diabete are overweight and obesity. Hyperglycemia almost due to insulin-resistance; In overweight and obese insulin-resistant individuals, modest weight loss has been shown to reduce insulin resistance. Lifestyle changes that include moderate weight loss and regular physical activity (150-300min/week), with dietary strategies including reduced calories and reduced intake of dietary fat, can reduce the risk for developing the complication of diabetes. Therefore, MNT and exercise are the firt choice and metformin. People with diabetes should receive diabetes self-management education to have a good effective in therapy for type 2 diabetes. According to the guidelines in the World, individuals who have type 2 diabetes should receive individualized medical nutrition therapy (MNT) and exercise as needed to achieve treatment goals. In 2008 and update in 2011, 2012, new guideline of the IDC, the ADA and the EASD published an expert consensus statement on the approach to management of hyperglycemia in individuals with type 2 diabetes. Highlights of this approach are: intervention at the time of diagnosis with metformin (monotherapy with metformin as the initial pharmacologic therapy for most patients with type 2 diabetes) in combination with lifestyle changes (MNT and exercise), and continuing timely augmentation of therapy with additional agents (including early initiation of insulin therapy) as a means of achieving and maintaining recommended levels of glycemic control (Fasting plasma glucose or preprandial: 70-130mg/dl, 2 hours posprandial: <180mg/dl and A1C <7% for most patients/3 months). As A1C targets are not achieved, treatment intensification is based on the addition of another agent from a different class (sulfonylureas, meglitinides, thiazolidinediones, DPP-4 inhibitors, and GLP-1 receptor antagonist, insulin). Diabetes in adults is associated with a high risk of macrovascular disease, with CVD the primary cause of death among people with type 2 diabetes. For prevention of cardiovascular events among type 2 diabetes (MI, stroke, PAD..), beside treatment hyperglycemia, we have also to reduce hyperlipidemia and hypertension
MICROSCOPIC-OBSERVATION DRUG-SUSCEPTIBILITY ASAY DETECTING RAPIDLY DRUG RESISTANT AND MULTIDRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS
Authors: Ngo Viet Quynh Tram , Nguyen Thi Chau Anh , Nguyen Hoang Bach , et al
Published: March 2020

Backround: Tuberculosis remains a major cause of morbidity and mortality in many countries and a significant public health problem worldwide. If TB is detected early and properly treated, the patients quickly become non-infectious and are eventually cured. Objective: Using MODS assay for detecting rapidly drug resistant and multidrug resistant M. tuberculosis. Methods: The MODS assay for the detection of tuberculosis and drug-resistant tuberculosis, directly from 252 sputum samples from suspected tuberculosis patients or untreated or ≤ 2 weeks treated tuberculosis patients. Culturing and doing susceptibility test by MODS assay (Issoniazid: 0.1 µg/ml; rifampicin: 1 µg/ml, Streptomycin: 2 µg/ml và Ethambutol: 2.5 µg/ml). Realtime PCR 16S was performed for the MODS culture-positive samples before 7 days and the samples with MODS culture-negative but AFB-positive. Results: M.tuberculosis was detected in 153 samples (60.7%) and 46 (30.1%) were antibiotic resistant. One drug resistance was present in 30 strains (19.6%): 18 for RIF, 6 for INH and 3 for STR and EBM. Multidrug resistant M.tuberculosis as defined by WHO (resistant to RIF and INH) was observed in 13 strains. There were additional 14 strains showing resistance to two or more drugs. Conclusion: The MODS assay is a rapid, direct method for simultaneous culture detection and drug susceptibility of M. tuberculosis, can be used as a routine procedure.
STUDYING OF SOME CLINICAL, BIOCHEMICAL CHARACTERISTICS AND TREATMENTS RESULTS OF CHOLERA PATIENTS IN BEN TRE PROVINCE IN 2010
Authors: Cao Thi My Nhon , Ho Thuy Kim Son , Le Thi Kim Loan , Tran Xuan Chuong
Published: March 2020

Objectives: Cholera is an emergent infection due to Vibrio cholerae. Studying clinical and biochemical characteristics of cholera helps doctors in diagnosis, treatment, following up and prognosis. Aims: 1. To determine some clinical and biochemical characteristics of cholera patients in 2010 epidemics in Ben Tre province. 2. To evaluate the relation of leucocytosis to diarrheal duration. Materials and methods: Patients diagnosed as cholera treated in Nguyen Dinh Chieu Hospital and Cu Lao Minh Hospital, Ben Tre province, since May 2010 to September 2010. Results: 54 patients were enrolled in this study (males 16, females 38). All patients had Ogawa positive. More than 60% pts stayed in hospitals over 96 hours. Most of pts had diarrheal duration over 48 hours, 44.5% more than 72 hours. 20.3% pts had water loss in level 3. 50% pts had leucocytosis, in them 16.7% had over 15.109/L. 18,5% had acute renal failure. Group with leucocytosis had higher rate of diarrhoea over 72 hours than group without leucocytosis (77.7% vs. 36%). Conclusions: 1. Most of pts had long diarrheal duration. 20.3% pts had water loss in level 3. 50% pts had leucocytosis, in them 16.7% had over 15.109/L. 18,5% had acute renal failure. 2. Leucocytosis may be related to the diarrheal duration.
RESEARCH ON CLINICAL MANIFESTATIONS AND AEROBIC BACTERIA OF ACUTE TONSILITIS IN HUE CENTRAL HOSPITAL AND HUE UNIVERSITY HOSPITAL
Authors: Truong Kim Tri , Nguyen Tu The , Vo Lam Phuoc
Published: March 2020

Objective: To study the paraclinical and clinical mannifestations, aerobic bacteria and antibiogramme of acute tonsilitis. Materials and method: A cross-sectional study was conducted upon 34 patients with acute tonsilitis at Hue Central hospital and of Hue University Hospital. Results: Clinical and paraclinical characteristics: odynophagy 94.1%, tonsillar hyperaemia 88.2%. Having treatment with antibiotics before hospitalization 50%. White blood cells >10-15.109/l (58.8%). Positive bacteria culture is 67.6% in which streptococcus β hemolytic group (A) 25%, streptococcus α hemolytic 25%, hemophilus influenzae 25%. Antibiogramme: Sensitization: gentamycin 100%, cefuroxim 100%, ceftriaxone 93.8%, cefalexin 90.9%, vancomycin 86.7%; Resistance: Tetracyclin 85.7%, erythromycin 69.2%, ofloxacin 42.9%, ampicillin 33.3%, ciprofloxacin 33.3%. Consclusions: The priority of antibiotic prescription for acute tonsilitis should be based on the frequency of bacteria found in bacteria culture and depending on antibiogramme to choose appropriate antibiotics.
A STUDY OF SOLUTIONS TO PREVENT THE EROSION OF THE MOSS GROWING ON ARCHITECTURES OF HUE IMPERIAL CITADEL
Authors: Nguyen Nhan Duc , Luong Cong Nho , Nguyen Hoang Vu
Published: March 2020

Background: The erosion of mosses on the surface of Hue imperial citadel has caused a lot of harm and is currently an urgent problem to be solved. Objectives:1. Identifying some moss species growing on Hue relics. 2. Determining the cause of slipperiness and the living environment mosses. 3. Finding a solution to limit the intrusion of the mosses. Methods: The methods are: identifying scientific name by comparing patterns, identify mucus, pH measurement and evaluation of the effects of certain chemicals on the growth of mosses in the laboratory. Result: The moss species that develop popularly in Hue relics is Funaria hygrometrica, Bryum apiculatum, Trichostomum orthodontum, Fissidens lycopodioides. Funaria hygrometrica is the most popular moss. The cause of the slipperiness is mucus in moss cells released outside the moss after death. Mosses grow well in moist environments, clear and slightly acidic surface. After two days assessing the effect of citric acid 18%, 15%, 10% and 7% NaHCO3, 5%, 3% on the growth of moss, the mosses all died completely. Since then identified two types of chemicals have been found to completely dead moss, inexpensive, environmentally friendly and does not affect the surface of architectures are citric acid 10% solution and NaHCO3 3% solution. Keywords: The moss erosion, Funaria hygrometrica, mucus, citric acid, NaHCO3
Key words: The moss erosion, Funaria hygrometrica, mucus, citric acid, NaHCO 3
THE EFFECT OF LECTURER PROFESSIONALISM AND TEACHING MOTIVATION ON LECTURERS STRENGTHENING THE NATION'S COMPETITIVENESS (SURVEY ON XYZ COLLEGE LECTURERS IN CENTRAL JAKARTA CITY)
Authors: Khasanah Khasanah
Published: March 2020

The purpose of this study was to determine the effect of Lecturer Professionalism and Motivation Teaching Lecturers equally against National Competitiveness in Higher Education XYZ in Central Jakarta. The research method used was a survey with correlation analysis and regression. Data on lecturer professionalism, teaching motivation, and national competitiveness obtained through a questionnaire compiled by researchers, namely those that measure things related to the three things above. The results showed: 1) There was an influence significant independent variable lecturer professionalism and lecturer teaching motivation together with the dependent variable of the nation's competitiveness. This is proven by the results of testing hypothesis through multiple regression analysis that the value of Sig = 0,000 and Fcount = 27,746, whereas F table = 3.25 so that the Sig value <0.05 and Fcount> F table which means the regression is significant. 2) There is a significant influence of the lecturer professionalism independent variable on the variable nation's competitiveness. This is evidenced by the results of testing the hypothesis obtained that the value Sig = 0.001 and tcount = 3.808, while table = 1.68 so the value of Sig <0.05 and tcount> table which means there is a significant influence. 3) There is a significant influence of variables free motivation to teach the nation's competitiveness variable. This is proven by the results Hypothesis testing obtained that the value of Sig = 0.001 and tcount = 3.772, while table = 1.68 so that the Sig value <0.05 and tcount> t table which means that there is an influence significant. The equation shows that there is an influence of professionalism lecturer on the nation's competitiveness.