bluuebunny/crossref_metadata_2025 huggingface dataset:
The Inflammatory Markers C-reactive Protein and Mean Platelet Volume in Chronic Kidney Disease
Authors:   Department of Nephrology, Murat State Hospital, Edirne, Turkey., Kılıç İlhan , Oğuz Taylan Elif Tuğba ,   Department of Internal Medicine, Murat State Hospital, Edirne, Turkey., Kurultak İlhan ,   Department of Nephrology, School of Medicine, Trakya University, Edirne, Turkey., Üstündağ Sedat ,   Department of Nephrology, School of Medicine, Trakya University, Edirne, Turkey.
Published: September 2023

Background: People with chronic kidney disease (CKD) experience chronic systemic inflammation. Although a relationship exists between inflammation and renal injury, the association between inflammatory markers and renal disease has not been well-studied. As inflammation may be a trigger or a result of chronic disease, the kidney needs to be investigated to determine whether it is a clearer target for the devastating effects of persistent inflammation. Here, we report the relation of C-reactive protein and mean platelet volume levels with renal functions in chronic kidney disease patients. Methods: This study was an observational retrospective single-center study conducted on the record of CKD patients to detect the outcomes over a median follow-up time of three years. Demographic, clinical, laboratory, medication, and outcome data were obtained from the electronic data records of the hospital. We investigated the multivariable association of plasma levels of C-reactive protein and mean platelet volume with the progression of CKD in the study participants. Findings: Elevated plasma levels of C-reactive protein (r=0.13, P<0.001) and mean platelet volume (r=0.23, P<0.001) were associated with a greater loss of kidney function over time. The presence of diabetes mellitus was detected to be a risk factor for CKD progression (P=0.04). An inverse relationship was detected between sodium and creatinine (P<0.001). In addition, a weak association was detected between uric acid and creatinine (P<0.001). Conclusion: Elevated plasma levels of C-reactive protein and mean platelet volume were associated with a decline in the estimated glomerular filtration rate in patients with CKD.
Humic and Fulvic Acids Induced Thermodynamic and Structural Instability of Tyrosinase With Antiproliferative Effect on A375 Melanoma Cancer Cell Line
Authors:   Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran., Taherkhani Negar , Piri Hossein ,   Cellular and Molecular Research Center, Research Institute for Prevention of Non-communicable Disease, Qazvin University of Medical Sciences, Qazvin, Iran., Hekmat Azadeh ,   Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran., Haghbeen Kamahldin ,   Department of Biochemistry and Biophysics, National Institute for Genetic Engineering and Biotechnology, Tehran, Iran.
Published: September 2023

Background: The tyrosinase enzyme catalysis monophenols to melanin pigments through the melanogenesis process. For this reason, various inhibitors have been studied for enzyme regulations in melanogenesis abnormalities in both the food and cosmetics industries. In this study, the effect of humic acid (Hu) and fulvic acid (Fu) on the structure, activity, and stability of mushroom tyrosinase (MT) was investigated. Methods: These two organic acids are the main components of soil humus. Assessment of the thermodynamic and structural stability of enzymes was obtained through thechemical and thermal denaturations and (8-anilino-naphthalene sulfonic acid) ANS fluorescence analysis. The Hu and Fu impact on A375 melanoma cancer cell viability was achieved by MTT assay. Findings: The results of enzyme half denaturation concentration (Cm), melting points (Tm), ΔG0 values and external fluorescence emissions in the presence of Hu and FA proved the reduction of the thermodynamic and structural stability of MT by these compounds. The anti-proliferation effects of the compounds were confirmed by the inhibitory concentrations of 50% (IC50) of 31.5 and 42.7 µM and 12.5 and µM at time points of 24 and 48 hours treatments of the A375 melanoma cell line by Hu and Fu, respectively. Conclusion: Humic and fulvic acids can be expected to contribute to advancing skin disorder science play a crucial role in tyrosinase related disorders and anti-cancer effects, and good candidates for medical applications.
Effect of Antioxidant on Sperm Freezing
Authors:   Students’ Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran., Zamani Maryam , Zafari Fariba ,   Cellular and Molecular Research Center, Research Institute for Presentation of Non-communicable Disease, Qazvin University of Medical Sciences, Qazvin, Iran., Najafzadeh Vahid ,   Queensland Fertility Group Research Foundation, Spring Hill, Queensland, Australia., Rajaei Farzad ,   Cellular and Molecular Research Center, Research Institute for Presentation of Non-communicable Disease, Qazvin University of Medical Sciences, Qazvin, Iran., Kamranjam Mana ,   Students’ Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran., Hosseini Amir ,   Cellular and Molecular Research Center, Research Institute for Presentation of Non-communicable Disease, Qazvin University of Medical Sciences, Qazvin, Iran.
Published: September 2023

A major cause of male infertility, which includes 50 causes of infertility, is oxidative stress. Aerobic respiration in the sperm cell is associated with the production of reactive oxygen species (ROS). Some reactions, such as sperm capacitation and acrosome reactions require moderate levels of ROS. However, when the amount of ROS production surpasses the natural antioxidant defense of the cell, it causes a harmful effect called oxidative stress. This results in the oxidation of lipids, proteins, carbohydrates, and nucleotides. The production of ROS is increased by various factors, including the presence of leukocytes, sperms with abnormal and immature morphology, centrifugation of samples, and changes in oxygen concentration, pH, and temperature. Sperm freezing is a method widely used in assisted reproductive technology (ART) as well as infertility treatment. The process of freezing also contributes to increased oxidative stress because it alters the fluidity of the mitochondrial membrane, leading to increased production and release of ROS. Sperm have defense mechanisms against oxidative stress caused by increased ROS production, which includes the presence of enzymatic and non-enzymatic antioxidants in semen. The utilization of supplementary antioxidants in the freezing environment is a strategy to combat oxidative stress. This review aims to summarize the current evidence on the effect of antioxidants on sperm freezing.
The effectiveness of the use of the feed additive “Butaselmevit-plus” as part of compound feed for young pigs
Authors: Martyshuk T. V. , Gutyj B. V. , Sobolieva S. V. , Khalak V. I. , Vozna O. Ye. , Todoriuk V. B.
Published: September 2023

The results of the production approval fully confirmed the high efficiency of introducing the feed additive “Butaselmevit-plus” into the compound feed for piglets. It was established that at the end of the piglet rearing period (at the age of 75 days), the average weight of one head in the experimental group was 32.6 kg, which is 1.1 kilograms or 3.5% higher (P < 0.05). Then their peers from the control group. During the period of rearing, the absolute increase in body weight in young animals of the experimental group was higher by 1.2 kg, or by 4.7 %, and the average daily weight gain by 21.8 g, or by 4.7 %, compared to similar indicators in piglets of the control group, and were 26.5 kg and 481.8 g, respectively. Among the numerous indicators determining the economic efficiency of production, the cost per unit of production is considered the most important. One of the reserves for reducing the cost of pig production is increasing young animals' productivity and preservation. The above results of the production inspection convincingly prove that using the feed additive “Butaselmevit-plus” in compound feed for piglets at the rate of 100 mg/kg of body weight increases their product qualities and, as a result, improves economic indicators. In the experimental group, the cost of 1 kg of live weight of piglets during rearing decreased by UAH 0.57, or 3.0 %, compared to the young of the control group and amounted to UAH 18.25. The cost of 1 kg of live weight gain in control and experimental groups was slightly higher (23.44 and 22.46 UAH, respectively), and the difference in favor of the latter was 4.2 %. The decrease in the unit cost of production in the experimental group was due to the increase in body weight and the survival of young pigs during the rearing period. The economic effect of using the feed additive “Butaselmevit-plus” as part of compound feed, calculated per 1 head of young pigs, was UAH 25.97 at the prices set for feed and feed additive in 2019. To increase the adaptability of piglets at an early age when weaning from the sow and to prevent the development of oxidative stress, for further maintenance during the period of rearing and fattening, it is recommended to use the feed additive “Butaselmevit-plus” in the amount of 100 mg/kg of body weight per day together with concentrates diet in the period from 21 to 40 days of age.
Accumulation lithium in the tissues and organs of goslings concerning of its level in the mixed feed
Authors: Sobolev O. I. , Gutyj B. V. , Sobolieva S. V. , Petryshak R. А. , Petryshak O. І. , Naumyuk О. S. , Melnychenko Y. O. , Guta Z. A. , Martyshuk T. V.
Published: September 2023

We studied the possibility of fortification of goslings’ products with lithium and peculiarities of its depositing in the organs and tissues of goslings concerning lithium level in the mixed feed. Experimental studies have been conducted on goose breed Legart. A total of 320 one-day-old goslings were divided on the principle of analogues into four groups and 80 heads each. The goslings of the first control group did not receive the lithium supplement with the feed mix. Experimental groups were fed with the feed mixed that additionally was supplemented with different doses of lithium by the scheme of the experiment. After 70 days of rearing, three birds were randomly selected from each group and their control slaughter. The lithium content in the representative samples of muscle tissue and organs of goslings was determined by inductively coupled plasma-atomic emission spectrometry (ICP-AES). It was established that feeding the growing goslings with mixed feed containing lithium supplements in doses of 0.05, 0.1 and 0.15 mg/kg, contributed to the increase (P < 0.001) of the concentration of this trace element in the muscles of the thigh and drumstick accordingly 789.5, 1589.5 and at 3447.4 %, in the muscles of the breast 1096.8, 2080.6 and at 3948.4 %, liver are 455.4, 824.6 and at 1440.8 % are compared to goslings that did not receive lithium supplements. Significantly high values of lithium accumulation factors in organs and tissues of gosling (3.21–14.44) indicated that this element has a substantial accumulating capacity. The meat of goslings enriched with lithium can be considered as a natural product with bio-corrective action that can be used in human nutrition. These meat products can be particularly useful for people that are living in regions with a low environmental level of lithium.
Nuevos registros de triatominos (Hemiptera: Reduviidae: Triatominae) en el municipio de General Zuazua, Nuevo León, México
Authors:   Universidad Autónoma de Nuevo León, México, Martínez-Pérez Gloria Elena , Martínez-Tovar José Gerardo ,   Instituto Tecnológico de Estudios Superiores de la Región Carbonífera, México, Dávila-Barbosa Jesús Antonio , Rodríguez-Sánchez Iram , Ramírez-Ahuja María de Lourdes , Hernández-Cabrera Francisco , Elías-Santos Myriam , Rebollar-Téllez Eduardo A.
Published: September 2023

Introducción. La enfermedad de Chagas es endémica en Latinoamérica y es causada por el parásito Trypanosoma cruzi. Los vectores son chinches de la subfamilia Triatominae. En México, se han identificado unas 31 especies y en Nuevo León existen seis especies en 23 de los 51 municipios del estado. Objetivo. El objetivo del presente estudio fue documentar nuevos registros de triatominos en el municipio de General Zuazua, Nuevo León. Materiales y métodos. La colecta de triatominos se realizó en una zona semi-urbana del municipio de General Zuazua, Nuevo León. En dos puntos de colecta separados por 150 m, se colocaron trampas tipo pantalla blancas de 1.5 x 1.5 m, iluminadas con luces blancas LED en horario de 1800 a 0700 h. Se registraron variables ambientales como temperatura del aire, temperatura del suelo, velocidad del aire, humedad relativa en cada sitio usando un termo-anemómetro. Los especímenes colectados fueron resguardados en recipientes de plástico de 30 ml de capacidad al cual se le añadió papel filtro circular en la base y una tira de papel filtro arreglado de forma acordeón. La chinche Paratriatoma lecticularia fue mantenida viva en el laboratorio y fue alimentada dos veces con sangre de ratón y las heces fueron examinadas para la búsqueda de tripromastigote metacíclico de Trypanosoma cruzi. Resultados. Se capturaron dos especies de triatominos Paratriatoma lecticularia y Triatoma gerstaeckeri. Conclusión. Ambas especies son nuevos registros para el municipio de General Zuazua, Nuevo León.
Topical treatment of cutaneous leishmaniasis using a nanoemulsion cream-based on generic pentavalent antimony. Case report
Authors:   Universidad de Los Andes, República Bolivariana de Venezuela, Anez Néstor , Bullón Johnny ,   Facultad de Ingeniería, Universidad de Los Andes, Mérida, República Bolivariana de Venezuela, Crisante Gladys ,   Facultad de Ciencias, Universidad de Los Andes, Mérida, República Bolivariana de Venezuela, Scorza-Dagert José Vicente ,   Instituto de Investigaciones “José Witremundo Torrealba”, Núcleo Universitario Rafael Rangel, Trujillo, Universidad de Los Andes, Trujillo, República Bolivariana de Venezuela, Véjar Francia , Forgiarini Ana
Published: September 2023

Introduction. An effective vaccine against cutaneous leishmaniasis has yet to be developed. Treatment of the disease relies on painful intramuscular administration of high doses of compounds based on pentavalent antimony, causing adverse effects. New therapeutic options effective, easy to apply, cheap and without adverse effects are urgently required. Case report. A 26-year-old male patient showing a large facial ulcer, presumptively by cutaneous leishmaniasis, diagnostic confirmed by Montenegro’s skin test and microscopical observation of amastigote forms. Due to the ulcer’s location and size, topical treatment with a nanoemulsion cream-based on a generic antimony-compound was attempted. The cream was applied twice daily and was rapidly absorbed. After 2 months of treatment, no discomfort or other adverse effects were detected. The ulcer was replaced with healthy skin tissue and a soft, clean scar. Conclusion. The novel cream, which was rapidly absorbed, effective, cheaper than standard systemic therapy and self-applied by the patient, showed potential value in the treatment of cutaneous leishmaniasis.
An Analysis of Primary School Students’ Reading Competence in Using Cohesive Devices
Authors: Jing Jinxiu
Published: September 2023

Cohesion devices are an important and key part of discourse analysis through English learning. Based on problems in current English reading classes in primary schools, like lack of critical thinking competence, broken lexical knowledge, or ineffective reading habits, this paper aims to call for the necessity of guiding primary school students to gradually strengthen the awareness of analyzing the cohesion devices in text reading so as to lay a sound foundation for their future literature appreciation.
HYDROLOGICAL LEGACIES OF COLONIALISM: EXAMINING WATER SYSTEMS IN PERLIS, MALAYA (1909–1950)
Authors: Abdullah DR. Mohd Firdaus , Mohd Noor Arba'iyah , Azlizan Mat Enh
Published: September 2023

This study focused on water management and control in Malaya, particularly the establishment of a ‘colonial hydrology’ in Perlisfrom 1909 to 1950. The study analysed water policies, management techniques, and the social and economic aspects of the localpopulation and the global market, using archival data. This study has also highlighted the intersection between natural resources, political power, and global economic trends from an international studies perspective. The control over water resources allowed the British colonial government to strengthen its position in the global market, but this resulted in adverse effects on the environment and social justice, especially for the local population. The study has argued that sustainable and equitable approaches to resource management are needed to promote sustainable development and combat global environmental challenges. The findings of this research can inform policymakers about the importance of incorporating environmental and social justice considerations in policymaking, especially with regard to natural resource management. Overall, this study adds valuable insights to the field of international studies by highlighting how the exploitation of natural resources can have far-reaching effects, both locally and globally, thereby emphasising the need for interdisciplinary and inclusive approaches to addressing resource management issues.
The Use of Machine Learning for the Purpose of Combating Bank Fraud
Authors:   State University of Moldova, Caprian Iurie
Published: September 2023

Machine learning is a specific field of artificial intelligence that allows an information system to learn and improve itself autonomously using neural networks and deep learning, without the need for explicit programming, by ingesting large amounts of data. With the deepening of banking activity at the global level in cyberspace, the problems of a different kind, which are considered bank frauds, have become substantially more acute. Combating them required the examination of a gigantic volume of information, which as a task can only be achieved with artificial intelligence solutions, including the use of automatic learning technologies. Systems based on automatic learning are capable not only of analyzing the available information, but also of making certain predictions and self-learning conclusions, which allows not only the detection of existing forms of bank fraud, but to a certain extent to prevent it by detecting anomalies in customer behavior. At the moment, the global information industry has developed different forms of automatic learning, which can be adapted to the detection of fraud in different forms of banking activity. The development, implementation and further development of banking information systems based on automatic learning requires the completion of certain stages and the observance of mandatory rules.
Formation of the Organization’s Information and Communication Management
Authors:   State University of Infrastructure and Technology, Semenchuk Tetiana B. , Osypova Yevheniia L. ,   State University of Infrastructure and Technologies, Topoliuk Hanna Yu. ,   State University of Infrastructure and Technologies
Published: September 2023

The article is aimed at studying and substantiating information and communication links and managing them in an organization, i. e. systematizing the entire communication space relating to enterprise management and promotion of goods and services. The article describes the meaning, value and place of information and communication management of organization as a process of making managerial decisions and promoting goods and services. As a result of all relevant research, the article forms a mechanism of information and communication management of organization, which allows to effectively manage information resources and communication processes at enterprise, which, in turn, provides improvement of productivity, efficiency, and competitiveness. The systematization of the classification of communications, which is presented in the article, depending on the type, environment of application and characterization of each of them, allows more effective use of all information and communication processes for the formation of a general organizational mechanism of communication links. The authors, after a thorough study of domestic and foreign opinions of scholars on information and communication management, provide their own vision of this category as an area of activity that studies, develops and implements strategies, methods and technologies for effective management of information resources and communication processes in an organization or enterprise. For formation of the mechanism of information and communication management, the article identifies the main aspects of formation of communication space of enterprise, namely: collection and processing of information; providing access to information and information security; communications management; information technology management; analysis and implementation of the latest solutions. Improving the information and communication management in enterprises can play an important role in improving the efficiency and productivity of the organization. Therefore, the article considers the main processes that will improve information and communication management at enterprises.
Startups: Essence, Classification, Role in the Economies of the World
Authors:   Research Centre of Industrial Problems of Development of NAS of Ukraine, Khaustov Mykyta M.
Published: September 2023

The article defines that startups in the modern economy, being the first stage of the life cycle of innovations, become one of the main engines of scientific progress. The purpose of the study is to determine the essence, classification, and role of startups in the economies of the world. Within the framework of this goal, the main approaches to defining the essence of startups are considered; a content analysis of the concept of «startup» is carried out; a closer definition of the concept is proposed. The main characteristics of «startups» and «small businesses» are also compared; the key features that allow a business project to be considered a startup are identified; the types and kinds of startups are studied. It concerns the following: low-tech, high-tech, and deep-tech innovations; startups by type of activity; depending on the stage of their life cycle; according to the main trends within which the startup will develop; by the method of occurrence (i. e., the nature of the action in the market); depending on their cost, etc. A generalized classification of types of startups by various attributes is proposed. Trends in the development of the startup movement are studied, viz.: rating by the share of startups in key topics; number of startups in the leading countries; the world-wide distribution of startups based on the industry of their implementation and their respective percentage of the total number. It is proved that the present-days processes of creating startups in the world are developing dynamically and will be of particular importance in those areas of the economy where structural transformation is central to the realization of not only economic but also broader social goals. It is determined that Ukraine cannot stay aside from these processes, which will require the use of various national policy instruments, the formation and development of the startup ecosystem, and the relevant institutional environment. This will create a basis for economic growth, which is extremely important for Ukraine in the context of the post-war economic recovery.
The Problem of Food Security for the Countries of the Middle East and Its Socioeconomic Dimension
Authors:   West Ukrainian National University, Nahirna Nadiia I. , Zastavnyy Andriy R. ,   West Ukrainian National University
Published: September 2023

The article deals with the actuality of the problem of food security, the complex nature of the problem is substantiated. It is confirmed that food security is connected with human right to food; therefore it should be supported by international organizations and countries. The state of food security, formation of which was affected by changes both in the global and regional context, was analyzed. The state of food security in the countries of the Middle East was studied through the prism of threats to food security that occurred against the background of demographic, climatic and security challenges. The relationship between food security and socioeconomic processes was clarified. The influence of insufficient productivity of agricultural sector, land degradation, limited access to water resources, conflicts, demographic and social factors on the state of food security in the region was analyzed. The role of supporting agricultural sector at the level of international organizations to increase the level of food security is ascertained. The main types of support for the development of agriculture were analyzed using OECD indicators and their evaluation was carried out for some countries in the Middle East. Measures to improve food security in the region that take in account attracting funds and implementing special programs were considered on the example of Turkey. Recommendations for improving agricultural policy, developing infrastructure, supporting agriculture and promoting innovative approaches to ensure food security in the region were suggested.
The Qualitative Modernization of Consulting Services in the Process of Foreign Investment in the Post-War Reconstruction of the Economy of Ukraine
Authors:   Kyiv National Economic University named after V. Hetman, Tsygankova Tetiana M. , Gordieieva Tamara F. ,   Kyiv National Economic University named after V. Hetman, Khotsynska Daria V. ,   Kyiv National Economic University named after V. Hetman
Published: September 2023

In the conditions of post-war recovery of Ukraine, the tasks of consulting companies that will be serving the processes of foreign investment of the economy will become much more complicated. The article is aimed at defining the current approaches to qualitative modernization of provision of consulting services to foreign investors and domestic recipients of funds on the basis of observance of the principles of sustainable development and technological innovations. In the process of research, general scientific research methods were used: generalization, abstraction, structural-system method, classification. Qualitative modernization of modern consulting services for participants in the process of foreign investment involves improving the quality of services taking into account the conception of sustainable development, the use of novel technologies, the introduction of compliance control into the activities of companies and the formation of a special (integrated) package of services. According to the current requirements on the part of foreign investors, compliance should be an obligatory component of corporate governance in their partner companies – being an effective instrument to combat dishonesty and comply with standards in three areas – E (environmental), S (social), G (governance), or ESG. Digitalization of consulting companies raises the quality and variety of services to a new level, providing increased productivity of consultants; providing the ability to operate with large amounts of information, solve previously inaccessible tasks; creating conditions for communication between investment project participants in real time, etc. An additional factor in ensuring the quality of services to foreign investors is the real possibility of communication and work with documentation in the native language of a foreign customer, taking into account the specifics of its linguistic and cultural environment. In further research, it is advisable to study in detail the experience of using the conception of ESG and compliance in the activities of foreign companies and its implementation in the activities of Ukrainian companies.
Formation of a Decentralized Model of Financial and Economic Regulation of Environmental Protection and Nature Management Activity: The Focus on European Experience
Authors:   Separated Subdivision of National University of Life and Environmental Sciences of Ukraine “Boyarka Forestry Research Station”, Holian Vasyl A. , Medynska Nataliia V. ,   National University of Life and Environmental Sciences of Ukraine, Moroz Yuliia O. ,   National University of Life and Environmental Sciences of Ukraine, Zamlynskyi Oleksandr S. ,   National University of Life and Environmental Sciences of Ukraine
Published: September 2023

It is found that in the context of martial law and deepening decentralization of power and local government reform, there is a need to form a decentralized model of financial and economic regulation of environmental management, which will allow more efficient accumulation of natural resource and environmental payments and ensure their targeted use in terms of expanded reproduction of natural resource potential and environmental protection. It is substantiated that a distinctive feature of the interbudgetary distribution of natural resource rent and environmental tax is their excessive centralization, which does not allow forming a sufficient financial base of local self-government for financial and investment support aimed at the reproduction of natural resource potential, development of a network of natural and economic and environmental infrastructure and environmental protection. It is identified that in 1999-2021, the dynamics of the proportion of local budgets in the total revenues of rent and fees for the use of other natural resources and environmental taxes to the Consolidated Budget of Ukraine shows a downward trend, which indicates the existence of gaps between the declared priorities of fiscal deregulation in the system of natural resource management and environmental protection and the actual decentralization of the accumulation of environmental payments in public budgets. It is found that the effectiveness of the decentralized model of financial and economic regulation of environmental management directly depends on the growth of the concentration of eco-resource payments in local budgets, which, in combination with the spatial and territorial communal assets, will allow diversifying the sources and methods of financial and investment support for rationalizing the use of natural raw materials and environmental protection in the adjacent territories. It is substantiated that the basis for building a decentralized model of financial and economic regulation of environmental management should be the Polish experience of organizing financial and investment support for environmental rehabilitation through the formation of a network of environmental protection funds at both the national and regional levels.
Literasi Kognitif Neurosains Guru Pendidikan Anak Usia Dini (PAUD) dalam Pembelajaran Matematika
Authors: Nurbaiti Nurbaiti , Apriyantoro Nursama Heru , Dumaris Corazon Hana , Prawestri Retno , Rizqi Muhamamd , Supriyoni Puji
Published: September 2023

ABSTRAK Pertumbuhan dan perkembangan otak anak membutuhkan perhatian agar dapat mendukung kecerdasan mereka di masa mendatang. Pemahaman tentang perkembangan otak anak sangat dibutuhkan dalam proses mendidik mereka pada usia dini. Poltekkes Kemenkes Jakarta II melaksanakan pelatihan bagi para guru Pendidikan Anak Usia Dini (PAUD) dalam pembelajaran matematika. Kegiatan ini bertujuan meningkatkan pengetahuan dan keterampilan para guru dalam proses pembelajaran matematika di kelas. Kegiatan ini diikuti oleh para guru dari enam sekolah PAUD di wilayah Kebayoran Baru dan Pesanggrahan, Jakarta Selatan. Mereka mengikuti 3 tahap kegiatan pelatihan dengan metode ceramah, diskusi, simulasi dan praktek. Hasil kegiatan ini memberikan mereka kesempatan untuk memperbaharui konsep dan metode pembelajaran matematika di sekolah, dan mengemasnya menjadi model belajar matematika yang sesuai dengan usia anak dengan metode yang menarik. Pengajaran atas dasar pemahaman perkembangan otak dalam neurosains membantu para guru menyusun bahan belajar dasar matematika yang tepat bagi anak usia dini.   Kata Kunci: Edukasi, Neurosains, Matematika Paud  ABSTRACT The growth and development of a child's brain requires attention in order to support their intelligence in the future. An understanding of children's brain development is very important in educating them at an early age. Poltekkes Kemenkes Jakarta II has conducted training for Early Childhood Education (PAUD) teachers in mathematics learning. This activity aims to increase the knowledge and skills of teachers in the process of learning mathematics in class. This activity was attended by teachers from six PAUD schools in the Kebayoran Baru and Pesanggrahan areas, South Jakarta. They took part in 3 stages of training activities using lecture and simulation methods. The results of this activities provided them with the opportunity to update the concepts and methods of learning mathematics at school, and package age-appropriate mathematics learning models in a variety of interesting ways. Teaching based on understanding brain development in neuroscience helped teachers develop appropriate basic mathematics learning materials for early childhood.     Keywords : Education, Neuroscience, Preschool Math
Pencegahan Karies Gigi melalui Deteksi Dini dan Cara Menyikat Gigi pada Anak Pra Sekolah
Authors: Modjo Dewi , Sudirman Andi Akifa , Indrianingsih Sofiyah Tri
Published: September 2023

ABSTRAK Perilaku untuk menjaga kesehatan gigi adalah dengan cara menggosok gigi. Pengenalan waktu dan cara menggosok gigi yang baik dan benar perlu dipahami oleh anak. Tujuan pengabdian ini yaitu untuk pencegahan karies gigi yang terjadi pada anak usia prasekolah di Desa Talumelito. Metode pengabdian yang dilakukan yaitu dengan Ceramah, Diskusi dan Demonstrasi. Hasil pelaksanaan edukasi, ada 2 materi yang disampaikan yaitu tentang pencegahan karies gigi dan Langkah-langkah yang benar dalam mengosok gigi. Pelaksanaan penyuluhan dihadiri oleh orangtua dan anak-anak usia prasekolah. Orangtua diajarkan terkait masalah yang muncul apabila tidak menjaga kesehatan gigi dan mulut sedangkan anak usia prasekolah diberikan demostrasi terkait cara mengosok gigi yang benar. Kesimpulan pada pengabdian ini adalah setelah edukasi pencegahan karies gigi dilakukan orangtua dan anak-anak antusias dalam mendemostrasikan cara mengosok gigi yang baik dan enar. Disarankan untuk dilakukan edukasi pada masyarakat terhadap faktor-faktor yang dapat menyebabkan karies gigi pada anak usia prasekolah namun juga pada seluruh lapisan masyarakat Kata Kunci : Karies gigi, Prasekolah   ABSTRACT The behavior to maintain healthy teeth is by brushing your teeth. Knowing when and how to brush your teeth properly and correctly needs to be understood by children. The purpose of this service is to prevent dental caries that occurs in preschool-aged children in Talumelito Village. The dedication method used is Lectures, Discussions and Demonstrations. As a result of the education implementation, there were 2 materials presented, namely about preventing dental caries and the correct steps for brushing your teeth. The extension was attended by parents and preschool age children. Parents are taught about the problems that arise if they do not maintain oral health, while preschoolers are given demonstrations regarding how to brush their teeth properly. The conclusion of this service is that after education on preventing dental caries, parents and children are enthusiastic in demonstrating how to brush their teeth properly and correctly. Recommended foreducation is carried out in the community about the factors that can cause dental caries in preschool-aged children but also at all levels of society. Keywords : Dental caries, Preschool
Peningkatan Kesehatan Pesisir pada Pra Lansia dan Lansia melalui Penyuluhan Hipertensi dan Pemeriksaan di PSRS Himo-Himo Ternate
Authors: The Fera , Permana Dini , Dika Sadrakh
Published: September 2023

ABSTRAK Hipertensi merupakan penyakit umum yang mengancam kesehatan masyarakat populasi dewasa dan lanjut usia. Upaya pencegahan hipertensi pada Pra Lansia dan Lansia dapat dilakukan dengan melakukan penyuluhan tentang bahaya serta pencegahan hipertensi serta pemeriksaan tekanan darah untuk skrining. Panti Sosial Rehabilitasi Sosial (PSRS) Himo-Himo Ternate adalah sebuah panti sosial tempat tinggal untuk pra lansia dan lansia. Dari segi usia, kelompok usia ini yang paling rentan terhadap penyakit tidak menular salah satunya yaitu tekanan darah tinggi (hipertensi). Pengabdian masyarakat ini bertujuan untuk meningkatakan kesehatan pra lansia dan lansia dengan metode penyuluhan hipertensi dan skrining tekanan darah melalui pemeriksaan. Pada pemeriksaan didapatkan tekanan darah normal sebanyak 16 orang, pre hipertensi sebanyak 7 orang, hipertensi grade 1 sebanyak 13 orang dan hipertensi grade 2 sebanyak 4 orang. Pentingnya peningkatan pengetahuan untuk pencegahan penyakit dan komplikasi Kata Kunci : Hipertensi, Lansia, Pra Lansia, PSRS Himo-Himo Ternate ABSTRACT Hypertension is a common disease that threatens the public health of the adult and elderly population. Efforts to prevent hypertension in the Pre-Elderly and Elderly can be carried out by conducting counseling about the dangers and prevention of hypertension and blood pressure checks for screening. Himo-Himo Ternate Social Rehabilitation Social Institution (PSRS) is a residential social institution for the pre-elderly and elderly. In terms of age, this age group is most vulnerable to non-communicable diseases, one of which is high blood pressure (hypertension). This community service aims to improve the health of the pre-elderly and elderly with hypertension counseling methods and blood pressure screening through examinations. On examination, normal blood pressure was found as many as 16 people, pre-hypertension as many as 7 people, grade 1 hypertension as many as 13 people and grade 2 hypertension as many as 4 people. The importance of increasing knowledge for the prevention of diseases and complications Keywords : Hypertension, Elderly, Pre-Elderly, PSRS Himo-Himo Ternate
Sosialisasi Pentingnya Tetap Menerapkan Pola Hidup Sehat dalam Meningkatkan Sistem Imun
Authors: Batubara Khairunnisa , Harahap Rahmat Ali Putra , Sinaga Elvipson , Siallagan Romauli
Published: September 2023

ABSTRAK Pola hidup sehat didapat dari mereka yang memperhatikan keadaan tubuhnya, rajin berolahraga, makan dan tidur yang cukup, hal ini menyebabkan tingkat kesehatan seseorang menjadi lebih baik, hal ini akan menjadikan kualitas hidup seseorang meningkat. Tujuan dari kegiatan pengabdian kepada masyarakat ini adalah membantu masyarakat Desa di Lingkungan XI Kelurahan Sei Agul, mengatasi persoalan-persoalan yang dihadapi saat ini dalam meningkatkan dan memelihara kesehatan dengan menerapkan pola hidup sehat. Metode yang akan digunakan dalam pengabdian masyarakat ini adalah melalui kegiatan penyuluhan agar masyarakat di Lingkungan XI Kelurahan Sei Agul dapat menerapkan pola hidup sehat. Selain itu, memberikan pelatihan-pelatihan dalam menjaga dan memelihara kesehatan tubuh agar terhindar dari berbagai macam penyakit (Public Healt Education). dari hasil pelatihan dan penyuluhan disimpulkan Hasil: masyarakat di lingkungan XI mengerti akan pentingnya menerapkan pola hidup sehat dalam meningkatkan system imun. Bahwa selama proses pelatihan masyarakat Lingkungan XI Kelurahan Sei Agul antusias mengikuti pelatihan. Saran: diharapkan dapat mengaplikasikan dalam kegiatan sehari-hari. Kata Kunci: Pola Hidup Sehat, Penyuluhan Kesehatan  ABSTRACT A healthy lifestyle is obtained from those who pay attention to the condition of their bodies, exercise diligently, eat and sleep enough, this causes a person's health level to be better, this will improve a person's quality of life. The purpose of this community service activity is to help village communities in the XI Sei Agul Village, overcome the problems they are currently facing in improving and maintaining health by adopting a healthy lifestyle. The method that will be used in this community service is through outreach activities so that people in the XI Sei Agul Subdistrict can adopt a healthy lifestyle. In addition, providing training in maintaining and maintaining a healthy body to avoid various diseases (Public Health Education). from the results of the training and counseling it was concluded Results: the community in the XI neighborhood understood the importance of adopting a healthy lifestyle in improving the immune system. Conclusion: that during the training process the people of the XI Neighborhood of the Sei Agul Village were enthusiastic about participating in the training. Suggestion: expected to be able to apply in daily activities. Keywords: Healthy Lifestyle, Health Education
Analisis Asuhan Keperawatan dengan Intervensi Penggunaan Silver Sebagai Primary Dressing pada Fase Proliferasi pada Klien Tn. W, Tn. S, dan Tn. Y dengan Diabetic Foot Ulcer di Klinik Wocare Center Kota Bogor
Authors: Sugiarti Dwi , Naziyah Naziyah
Published: September 2023

ABSTRAK Diabetic foot ulcer merupakan salah satu komplikasi yang umum terjadi pada penderita diabetes mellitus yang tidak terkontrol dengan baik. Masalah keperawatan utama yang ditemukan pada Tn. W, Tn. S, dan Tn. Y adalah gangguan integritas jaringan yang dibuktikan dengan adanya data subjektif dan objektif pada tanda dan gejala mayor yang berupa adanya ulkus diabetikum pada kaki klien. Menganalisis asuhan keperawatan dengan intervensi penggunaan silver pada klien dengan diabetic foot ulcer. Studi kasus dengan menganalisis pemberian silver sebagai primary dressing pada fase proliferasi pada tiga klien dengan diabetic foot ulcer di Klinik Wocare Center Bogor. Terdapat perubahan pada ukuran luka, granulasi, dan epitelisasi setelah diberikan silver sebanyak dua kali kunjungan. Silver dapat melembabkan dan membantu mempercepat proses pertumbuhan jaringan granulasi. Penggunaan silver sebagai primary dressing pada diabetic foot ulcer saat fase proliferasi efektif dalam mempersingkat perkiraan waktu penyembuhan luka yang ditandai dengan adanya perubahan ukuran luka, granulasi, dan epitelisasi yang cukup signifikan. Silver dapat sebagai bahan acuan untuk penanganan diabetic foot ulcer fase proliferasi. Kata Kunci: Diabetic Foot Ulcer, Primary Dressing, Silver  ABSTRACT Diabetic foot ulcer is a common complication in patients with diabetes mellitus who are not well controlled. The main nursing problem found in Mr. W, Mr. S, and Mr. Y is a disruption of network integrity as evidenced by the existence of subjective and objective data on major signs and symptoms in the form of a diabetic ulcer on the client's leg. To analyze nursing care with interventions using silver in clients with diabetic foot ulcers. Case study by analyzing the administration of silver as a primary dressing in the proliferation phase of three clients with diabetic foot ulcers at the Bogor Wocare Center Clinic. There were changes in wound size, granulation, and epithelialization after being given silver for two visits. Silver can moisturize and help accelerate the growth process of granulation tissue. The use of silver as a primary dressing for diabetic foot ulcers during the proliferative phase is effective in shortening the estimated wound healing time which is characterized by significant changes in wound size, granulation, and epithelialization. Silver can be used as a reference for the treatment of diabetic foot ulcers in the proliferative phase. Keywords: Diabetic Foot Ulcer, Primary Dressing, Silver
Pemanfaatan Media Digital sebagai Upaya Media Promosi dan Pemasaran pada Ikm Ibu Sri Kabupaten Minahasa
Authors: Olii Djami , Hasibuan Alfiansyah , Hibrida Anas Romzy
Published: September 2023

ABSTRAK Ibu Sri merupakan salah satu masyarakat yang memiliki Usaha Mikro Kecil dan Menengah (UMKM) yang bergerak pada pembuatan keripik tempe, pisang dan umbi-umbian, sumber bahan yang digunakan adalah hasil panen dari petani yang di jual oleh ibu sri. UMKM ini masih terdapat banyak permasalahan, diantaranya, Pandemi Covid-19 membuat pendapatan menurun, Jangkauan Pemasaran Hasil produksi belum luas, Belum ada sertifikasi halal dari Kemenag. Kegiatan yang dilakukan pada pengabdian ini dengan membangun sistem berbasis digital. Dalam menyelesaikan permasalah mitra, ada beberapa solusi yang direncanakan. Solusi tersebut meliputi, Membuat sistem berbasis digital yang dapat membantu dalam proses promosi dan pemasaran dengan jangkauan yang lebih luas, memberikan pelatihan manajemen pemasaran, melakukan proses pendampingan produk halal. Metode yang digunakan dalam pengabidan kepada masyarakat adalah ceramah (berupa pemberian teori) dan praktik penggunaan sistem digital. Hasil dari kegiatan pengabdian ini adalah pelaksana kegiatan telah memberikan pelatihan penggunaan sistem yang akan digunakan oleh UMKM dan mendapat antusiasme pelaku usaha untuk menggunakan sistem digital sebagai upaya peningkatan penjualan produk yang dihasilkan oleh UMKM, serta telah terlaksananya sosialisasi pendampingan sertifikasi halal bagi produk UMKM. Kata Kunci: Ibu Sri, UMKM, Covid-19, Sistem, Sertifikasi  ABSTRACT Mrs. Sri is one of the people who have Micro, Small, and Medium Enterprises (UMKM) which are engaged in making tempeh chips, bananas, and tubers. The source of the materials used are harvests from farmers which are sold by Mrs. Sri. These UMKM still have many problems, including, the Covid-19 pandemic has made income decrease, the marketing reach of production is not yet wide, and there is no halal certification from the Ministry of Religion. Activities carried out in this service by building a digital-based sistem. In solving partner problems, there are several planned solutions. These solutions include Creating a digital-based sistem that can assist in the promotion and marketing process with a wider range, providing marketing management training, and carrying out the process of mentoring halal products. The method used in community service is lectures (in the form of giving theory) and practical use of digital sistems. The results of this service activity are that the executors of the activities have provided training on the use of the sistem that will be used by UMKM and got the enthusiasm of business actors to use the digital sistem as an effort to increase sales of products produced by UMKM, and socialization of halal certification assistance has been carried out for UMKM products.  Keywords: Mrs. Sri, UMKM, Covid-19, System, Certification
Penyuluhan Stunting dan Upaya Pencegahannya
Authors: Gustaman Firman , Nurdianti Lusi , Wulandari Winda Trisna , Sugiharti Mulya Tri , Cahyani Intan Gita , Safitri Nurfaiza , Naqiah Zahrotun , Wildan Reza Ariza , Ramdani Bagas Pra
Published: September 2023

ABSTRAK Stunting merupakan perkara kurang gizi kronis yang ditimbulkan kurangnya asupan gizi dalam jangka waktu lama, sehingga menyebabkan gangguan pertumbuhan pada anak yaitu tinggi badan anak lebih rendah atau pendek (kerdil) dari standar usianya. Tujuan dari kegiatan penyuluhan stunting yang dilaksanakan adalah untuk meningkatkan pengetahuan dan pemahaman mengenai stunting pada anak serta upaya pencegahannya. Metode yang dipakai adalah dengan penyuluhan berupa pemaparan materi tentang pengertian stunting hingga pencegahan dan penanganan seperti prinsip dasar panduan makan gizi seimbang kepada ibu-ibu posyandu  Desa Cidugaleun. Berdasarkan hasil analisis uji statistik Wilcoxon, dapat ditarik kesimpulan bahwa terdapat perbedaan yang signifikan antara sebelum dan sesudah dilaksanakannya kegiatan. Kata Kunci : Stunting, Balita, Penyuluhan  ABSTRACT Stunting is a case of chronic malnutrition caused by lack of nutritional intake in the long term, causing growth disorders in children, namely the child's height is lower or shorter (short) than the standard age. The purpose of the stunting counseling activities carried out is to increase knowledge and understanding of stunting in children and its prevention efforts. The method used is counseling in the form of presentation of material on the meaning of stunting to prevention and treatment such as basic principles of balanced nutrition eating guidelines for posyandu mothers in Cidugaleun Village. Based on the results of the Wilcoxon statistical test analysis, it can be concluded that there is a significant difference between before and after the activity. Keywords: Stunting, Toddlers, Counseling