bluuebunny/crossref_metadata_2025 huggingface dataset:
Medieval Modal Spaces
Authors: Pasnau I—Robert
Published: March 2020

There is often said to be something peculiar about the history of modal theory up until the turn of the fourteenth century, when John Duns Scotus decisively reframed the issues. I wish to argue that this impression of dramatic discontinuity is almost entirely a misimpression. Premodern philosophers prescind from the wide-open modal space of all possible worlds because they seek to adapt their modal discourse to the explanatory and linguistic demands of their context.
Direct modeling of the crude probability of cancer death and the number of life years lost due to cancer without the need of cause of death: a pseudo-observation approach in the relative survival setting
Authors: Kipourou Dimitra-Kleio , Perme Maja Pohar , Rachet Bernard , Belot Aurelien
Published: March 2020

In population-based cancer studies, net survival is a crucial measure for population comparison purposes. However, alternative measures, namely the crude probability of death (CPr) and the number of life years lost (LYL) due to death according to different causes, are useful as complementary measures for reflecting different dimensions in terms of prognosis, treatment choice, or development of a control strategy. When the cause of death (COD) information is available, both measures can be estimated in competing risks setting using either cause-specific or subdistribution hazard regression models or with the pseudo-observation approach through direct modeling. We extended the pseudo-observation approach in order to model the CPr and the LYL due to different causes when information on COD is unavailable or unreliable (i.e., in relative survival setting). In a simulation study, we assessed the performance of the proposed approach in estimating regression parameters and examined models with different link functions that can provide an easier interpretation of the parameters. We showed that the pseudo-observation approach performs well for both measures and we illustrated their use on cervical cancer data from the England population-based cancer registry. A tutorial showing how to implement the method in R software is also provided.
Workplace Violence Against Domestic and Family Violence and Sexual Assault Workers: A Gendered, Settings-Based Approach
Authors: Natalier Kristin , Cortis Natasha , Seymour Kate , Wendt Sarah , King Debra
Published: March 2020

Violence against social workers and other social service practitioners is prevalent across countries and service delivery settings, often accepted as implicit in working with vulnerable clients. A corresponding scholarly focus on workplace violence, and the factors that affect it, is, however, still developing. This is particularly stark in the domestic and family violence (DFV) and sexual assault (SA) sectors. To address this gap, this article explores the extent and impact of practitioners’ exposure to workplace violence, and the mix of work and organisational factors that predict it. Analysis of survey data from Australian DFV and SA practitioners (N = 903) enables a focus on the two main sources of workplace violence: violence from clients and violence from colleagues. Both types of violence were found to be prevalent, gendered and associated with emotional strain and intention to leave. We argue that in DFV and SA sectors, which respond to multiple forms of gendered violence, understanding the multifaceted nature of workplace violence, and the structural arrangements that underpin it, is necessary for planning strategies to prevent and address it.
The Role of Applied Theatre in Social Work: Creative Interventions with Homeless Individuals
Authors: Muñoz-Bellerín Manuel , Cordero-Ramos Nuria
Published: March 2020

This article explores how creative theatre is used in the area of social work with homeless individuals in Seville (Spain). We look at how applied theatre can be used as a tool for encouraging the development of capacities amongst this group, which is largely excluded from mainstream society. To do this, we focus on our experiences in this area, with the aim of showing how social work and theatre can combine to form a powerful tool for fostering the development of agency and empowerment at an individual and group level. We also explain how theatrical performances are able to create spaces where homeless individuals and mainstream society are able to interact with one another beyond strictly institutional settings.
Prion protein codon 129 polymorphism in mild cognitive impairment and dementia: the Rotterdam Study
Authors: Karamujić-Čomić Hata , Ahmad Shahzad , Lysen Thom S , Heshmatollah Alis , Roshchupkin Gennady V , Vernooij Meike W , Rozemuller Annemieke J M , Ikram Mohammad Arfan , Amin Najaf , van Duijn Cornelia M
Published: March 2020

Creutzfeldt–Jakob disease is a rare, fatal, neurodegenerative disease caused by the accumulation of abnormally folded prion proteins. The common polymorphism at codon 129 (methionine/valine) in the prion protein (PRNP) gene is the most important determinant of genetic susceptibility. Homozygotes of either allele have a higher risk of sporadic Creutzfeldt–Jakob disease. Various studies suggest that this polymorphism is also involved in other forms of dementia. We studied the association between the codon 129 polymorphism of the PRNP gene and mild cognitive impairment in 3605 participants from the Rotterdam Study using logistic regression analyses. Subsequently, we studied the association between this polymorphism and incident dementia, including Alzheimer’s disease, in 11 070 participants using Cox proportional hazard models. Analyses were adjusted for age and sex. We found the prevalence of mild cognitive impairment to be higher for carriers of the methionine/methionine genotype (odds ratio, 1.40; 95% confidence interval, 1.11–1.78; P = 0.005) as well as for carriers of the valine/valine genotype (odds ratio, 1.37; 95% confidence interval, 0.96–1.97; P = 0.08). The codon 129 polymorphism was not associated with the risk of incident dementia or Alzheimer’s disease. In conclusion, we found a statistically significant higher prevalence of mild cognitive impairment in carriers of the methionine/methionine genotype in the codon 129 polymorphism of the PRNP gene within this population-based study. No associations were found between the codon 129 polymorphism and dementia or Alzheimer’s disease in the general population.
The impact of preoperative sarcopenia on postoperative complications following esophagectomy for esophageal neoplasia: a systematic review and meta-analysis
Authors: Papaconstantinou Dimitrios , Vretakakou Konstantina , Paspala Anna , Misiakos Evangelos P , Charalampopoulos Anestis , Nastos Constantinos , Patapis Paul , Pikoulis Emmanouil
Published: March 2020

Esophageal cancer is characterized by profound changes in body composition due to dysphagia and generalized cachexia. Sarcopenia or muscle wasting is a component of cachexia associated with poor postoperative performance status. The skeletal muscle index (SMI) calculated by computed tomography scans at the level of the third lumbar vertebra is an easily quantifiable and reproducible measure of sarcopenia. The aim of this meta-analysis is to investigate the impact of preoperative sarcopenia (low SMI) on postoperative complications after esophagectomy for neoplastic lesions. In this context, a comprehensive literature search was undertaken to identify studies reporting short-term postoperative outcomes in relation to their preoperative SMI values. Cumulative risk ratios (RR) and risk differences (RD) and their respective 95% confidence intervals (CIs) were calculated using a random-effect model. A total of 11 studies incorporating 1,979 total patients (964 patients with sarcopeniaversus 1,015 without sarcopenia) were included in the final analysis. The results demonstrated a significant increase in overall morbidity (RR 1.16, 95% CI 1.01–1.33), respiratory complications (RR 1.64, 95% CI 1.21–2.22) and anastomotic leaks (RR 1.39, 95% CI 1.10–1.76) in patients with sarcopenia. No statistically significant difference was noted in overall mortality (RD 0, 95% CI −0.02–0.02) or Clavien–Dindo grade III or greater complications (RR 1.17, 95% CI 0.96–1.42). The above results demonstrate the validity of the SMI as a predictive factor for post-esophagectomy complications. Although the risk associated with sarcopenia is not prohibitive for surgery, patients with low SMI require closer vigilance during their postoperative course due to the increased propensity for respiratory and anastomotic complications.
Development of a multivariable prediction model for patient-adjusted aortic risk morphology
Authors: Krüger Tobias , Boburg Rodrigo Sandoval , Hamdoun Hasan , Oikonomou Alexandre , Bongers Malte N , Schlensak Christian
Published: March 2020

OBJECTIVES

Preventing type A aortic dissection requires reliable prediction. We developed and validated a multivariable prediction model based on anthropometry to define patient-adjusted thresholds for aortic diameter and length.

METHODS

We analysed computed tomography angiographies and clinical data from 510 control patients, 143 subjects for model validation, 125 individuals with ascending aorta ectasia (45–54 mm), 58 patients with aneurysm (≥55 mm), 206 patients with type A aortic dissection and 19 patients who had received a computed tomography angiography ≤2 years before they suffered from a type A aortic dissection. Computed tomography angiographies were analysed using curved planar reformations.

RESULTS

In the control group, the mean ascending aortic diameter was 33.8 mm [standard deviation (SD) ±5.2 mm], and the length, measured from the aortic valve to the brachiocephalic trunk, was 91.9 mm (SD ±12.2 mm); both diameter and length were correlated with anthropometric parameters and were smaller than the respective values in all pathological groups (P < 0.001). Multivariable linear regression analysis of the control group revealed that age, sex and body surface area were predictors of ascending aorta diameter (R2 = 0.40) and length (R2 = 0.26). Bicuspidity of the aortic valve was not included in the model; its prevalence was only 3.2% in the control group but >25% in the ectasia and aneurysm groups.

CONCLUSIONS

The regression model provides a patient-adjusted prediction of the thresholds for aortic diameter and length. In our retrospective data, the model resulted in better identification of aortas at the risk of dissection than the conventional 55-mm diameter threshold. The model is available as an Internet calculator (www.aorticcalculator.com).
Investment Contracts and International Law: Charting a Research Agenda
Authors: Cotula Lorenzo
Published: March 2020

Investment contracts are an important part of the web of legal relations that underpin investment processes. They raise complex doctrinal issues, including with regard to their interface with public international law. The two books under review are part of a new surge in academic writing about investment contracts, in a field that is currently dominated by concerns about investment treaties and treaty-based arbitration. In this review essay, I explore the intersections between investment contracts and international law, engaging with the arguments presented in the two books and developing reflections based on trends in the wider literature. After situating the contract in academic and policy debates about international investment law, I compare the different approaches the two books embody – in relation to their scope, focus and format as well as the ways in which they conceptualize and piece together the multiple commercial and public interests at stake in investment contracting. I then discuss one theme that features prominently in both books – namely, the legal contours of investment protection, particularly in connection with stabilization clauses – and I examine its articulation with public regulatory powers. I conclude by outlining areas that deserve further exploration in scholarly work on investment contracts and international law.
Inferring Tunicate Relationships and the Evolution of the Tunicate Hox Cluster with the Genome of Corella inflata
Authors: DeBiasse Melissa B , Colgan William N , Harris Lincoln , Davidson Bradley , Ryan Joseph F
Published: March 2020

Tunicates, the closest living relatives of vertebrates, have served as a foundational model of early embryonic development for decades. Comparative studies of tunicate phylogeny and genome evolution provide a critical framework for analyzing chordate diversification and the emergence of vertebrates. Toward this goal, we sequenced the genome of Corella inflata (Ascidiacea, Phlebobranchia), so named for the capacity to brood self-fertilized embryos in a modified, “inflated” atrial chamber. Combining the new genome sequence for Co. inflata with publicly available tunicate data, we estimated a tunicate species phylogeny, reconstructed the ancestral Hox gene cluster at important nodes in the tunicate tree, and compared patterns of gene loss between Co. inflata and Ciona robusta, the prevailing tunicate model species. Our maximum-likelihood and Bayesian trees estimated from a concatenated 210-gene matrix were largely concordant and showed that Aplousobranchia was nested within a paraphyletic Phlebobranchia. We demonstrated that this relationship is not an artifact due to compositional heterogeneity, as had been suggested by previous studies. In addition, within Thaliacea, we recovered Doliolida as sister to the clade containing Salpida and Pyrosomatida. The Co. inflata genome provides increased resolution of the ancestral Hox clusters of key tunicate nodes, therefore expanding our understanding of the evolution of this cluster and its potential impact on tunicate morphological diversity. Our analyses of other gene families revealed that several cardiovascular associated genes (e.g., BMP10, SCL2A12, and PDE2a) absent from Ci. robusta, are present in Co. inflata. Taken together, our results help clarify tunicate relationships and the genomic content of key ancestral nodes within this phylogeny, providing critical insights into tunicate evolution.
Relating strain localization and Kaiser effect to yield surface evolution in brittle rocks
Authors: Gajst Hannah , Shalev Eyal , Weinberger Ram , Marco Shmuel , Zh Wenlu , Lyakhovsky Vladimir
Published: March 2020

The yield surfaces of rocks keep evolving beyond the initial yield stress owing to the damage accumulation and porosity change during brittle deformation. Using a poroelastic damage rheology model, we demonstrate that the measure of coupling between the yield surface change and accumulated damage is correlated with strain localization and the Kaiser effect. Constant or minor yield surface change is associated with strong strain localization, as seen in low-porosity crystalline rocks. In contrast, strong coupling between damage growth and the yield surface leads to distributed deformation, as seen in high-porosity rocks. Assuming that during brittle deformation damage occurs primarily in the form of microcracks, we propose that the measured acoustic emission (AE) in rock samples correlates with the damage accumulation. This allows quantifying the Kaiser effect under cyclic loading by matching between the onset of AE and the onset of damage growth. The ratio of the stress at the onset of AE to the peak stress of the previous loading cycle, or Felicity Ratio (FR), is calculated for different model parameters. The results of the simulation show that FR gradually decreases in the case of weak coupling between yield surface and damage growth. For a strong damage-related coupling promoting significant yield surface change, the FR remains close to one and decreases only towards the failure. The model predicts that a steep decrease in FR is associated with a transition between distributed and localized modes of failure. By linking the evolving yield surface to strain localization patterns and the Kaiser effect, the poroelastic damage rheology model provides a new quantitative tool to study failure modes of brittle rocks.
Sustained Ultrastructural Changes in Rat Hippocampal Formation After Repeated Electroconvulsive Seizures
Authors: Chen Fenghua , Danladi Jibrin , Wegener Gregers , Madsen Torsten M , Nyengaard Jens R
Published: March 2020

Background

Electroconvulsive therapy (ECT) is a highly effective and fast-acting treatment for depression used in the clinic. Its mechanism of therapeutic action remains uncertain. Previous studies have focused on documenting neuroplasticity in the early phase following electroconvulsive seizures (ECS), an animal model of ECT. Here, we investigate whether changes in synaptic plasticity and nonneuronal plasticity (vascular and mitochondria) are sustained 3 months after repeated ECS trials.

Methods

ECS or sham treatment was given daily for 1 day or 10 days to a genetic animal model of depression: the Flinders Sensitive and Resistant Line rats. Stereological principles were employed to quantify numbers of synapses and mitochondria as well as length of microvessels in the hippocampus 24 hours after a single ECS. Three months after 10 ECS treatments (1 per day for 10 days) and sham-treatment, brain-derived neurotrophic factor and vascular endothelial growth factor protein levels were quantified with immunohistochemistry.

Results

A single ECS treatment significantly increased the volume of hippocampal CA1-stratum radiatum, the total length of microvessels, mitochondria number, and synapse number. Observed changes were sustained as shown in the multiple ECS treatment group analyzed 3 months after the last of 10 ECS treatments.

Conclusion

A single ECS caused rapid effects of synaptic plasticity and nonneuronal plasticity, while repeated ECS induced long-lasting changes in the efficacy of synaptic plasticity and nonneuronal plasticity at least up to 3 months after ECS.
Asymptotic analysis of internal relaxation oscillations in a conceptual climate model
Authors: Płociniczak Łukasz
Published: March 2020

We construct a dynamical system based on the Källén–Crafoord–Ghil conceptual climate model which includes the ice–albedo and precipitation–temperature feedbacks. Further, we classify the stability of various critical points of the system and identify a parameter which change generates a Hopf bifurcation. This gives rise to a stable limit cycle around a physically interesting critical point. Moreover, it follows from the general theory that the periodic orbit exhibits relaxation-oscillations that are a characteristic feature of the Pleistocene ice ages. We provide an asymptotic analysis of their behaviour and derive a formula for the period along with several estimates. They, in turn, are in a decent agreement with paleoclimatic data and are independent of any parametrization used. Whence, our simple but robust model shows that a climate may exhibit internal relaxation oscillations without any external forcing and for a wide range of parameters.
Littlewood’s Problem for Sets with Multidimensional Structure
Authors: Hanson Brandon
Published: March 2020

We give $L^1$-norm estimates for exponential sums of a finite sets $A$ consisting of integers or lattice points. Under the assumption that $A$ possesses sufficient multidimensional structure, our estimates are stronger than those of McGehee–Pigno–Smith and Konyagin. These theorems improve upon past work of Petridis.
A Randomized Dose-Escalating Phase I Trial of a Replication-Deficient Lymphocytic Choriomeningitis Virus Vector-Based Vaccine Against Human Cytomegalovirus
Authors: Schwendinger Michael , Thiry Georges , De Vos Beatrice , Leroux-Roels Geert , Bruhwyler Jacques , Huygens Ariane , Ganeff Corinne , Buchinger Heidemarie , Orlinger Klaus K , Pinschewer Daniel D , Monath Thomas P , Lilja Anders E
Published: March 2020

Background

A vaccine (HB-101) consisting of 2 nonreplicating lymphocytic choriomeningitis virus (LCMV) vectors expressing the human cytomegalovirus antigens glycoprotein B (gB) and the 65-kD phosphoprotein (pp65), respectively, is in development to prevent cytomegalovirus infection.

Methods

HB-101 was tested in cytomegalovirus-naive, healthy adults in a randomized, double-blind, placebo-controlled, dose-escalation Phase I trial. Fifty-four subjects received low, medium, or high dose of HB-101 or placebo by intramuscular administration at Month 0, 1, and 3. Safety and immunogenicity were the respective primary and secondary endpoints. Subjects were followed for 12 months after the initial immunization.

Results

Vaccination was associated with transient mild to moderate adverse events. HB-101 administration induced dose-dependent gB- and pp65-specific cellular responses, dominated by pp65-specific CD8 T cells, a high fraction of which were polyfunctional. Two administrations were sufficient to elicit dose-dependent gB-binding and cytomegalovirus-neutralizing antibodies (Abs). Cytomegalovirus-specific immune responses were boosted after each administration. Only 1 of 42 vaccine recipients mounted a transient LCMV vector-neutralizing Ab response.

Conclusions

HB-101 was well tolerated and induced cytomegalovirus-specific polyfunctional CD8 T-cell and neutralizing Ab responses in the majority of subjects. Lack of vector-neutralizing Ab responses should facilitate booster vaccinations. These results justify further clinical evaluation of this vaccine candidate.
Human brain microvascular endothelial cell pairs model tissue-level blood–brain barrier function
Authors: O’Connor Blakely B , Grevesse Thomas , Zimmerman John F , Ardoña Herdeline Ann M , Jimenez Jorge A , Bitounis Dimitrios , Demokritou Philip , Parker Kevin Kit
Published: March 2020

The blood–brain barrier plays a critical role in delivering oxygen and nutrients to the brain while preventing the transport of neurotoxins. Predicting the ability of potential therapeutics and neurotoxicants to modulate brain barrier function remains a challenge due to limited spatial resolution and geometric constraints offered by existing in vitro models. Using soft lithography to control the shape of microvascular tissues, we predicted blood–brain barrier permeability states based on structural changes in human brain endothelial cells. We quantified morphological differences in nuclear, junction, and cytoskeletal proteins that influence, or indicate, barrier permeability. We established a correlation between brain endothelial cell pair structure and permeability by treating cell pairs and tissues with known cytoskeleton-modulating agents, including a Rho activator, a Rho inhibitor, and a cyclic adenosine monophosphate analog. Using this approach, we found that high-permeability cell pairs showed nuclear elongation, loss of junction proteins, and increased actin stress fiber formation, which were indicative of increased contractility. We measured traction forces generated by high- and low-permeability pairs, finding that higher stress at the intercellular junction contributes to barrier leakiness. We further tested the applicability of this platform to predict modulations in brain endothelial permeability by exposing cell pairs to engineered nanomaterials, including gold, silver–silica, and cerium oxide nanoparticles, thereby uncovering new insights into the mechanism of nanoparticle-mediated barrier disruption. Overall, we confirm the utility of this platform to assess the multiscale impact of pharmacological agents or environmental toxicants on blood–brain barrier integrity.
Unfolding the Past, Proving the Present: Social Media Evidence in Terrorism Finance Court Cases
Authors: Anwar Tasniem
Published: March 2020

During terrorism trials, social media activities such as tweeting, Facebook posts, and WhatsApp conversations have become an essential part of the evidence presented. Amidst the complexity of prosecuting crimes with limited possibilities for criminal investigations and evidence collection, social media interactions can provide valuable information to reconstruct events that occurred there-and-then, to prosecute in the here-and-now. This paper follows social media objects as evidentiary objects in different court judgments to research how security practices and knowledge interact with legal practices in the court room. I build on the notion of the folding object as described by Bruno Latour and Amade M'charek to research the practices and arguments of the judges through which they unfold some of the histories, interpretations, and politics inside the object as reliable evidence. This concept allows for an in-depth examination of how histories are entangled in the presentation of an evidentiary object and how these references to histories are made (in)visible during legal discussions on security and terrorism. The paper therefore contributes to the field of critical security studies by focusing on how security practices are mediated in the everyday legal settings of domestic court rooms.
Salmonella Contamination of Seafood in Landing Centers and Retail Markets of Mumbai, India
Authors: Prabhakar Parmanand , Lekshmi Manjusha , Ammini Parvathi , Nayak Binaya Bhusan , Kumar Sanath
Published: March 2020

Background

Seafood contamination with Salmonella enterica is not only a public health concern, but can also lead to economic losses due to import rejections. Continuous monitoring of seafood for Salmonella is necessary for risk assessment and to establish suitable control measures.

Objective

The objective of this study was to determine the extent of Salmonella contamination of seafood in fish landing centers and retails markets.

Methods

In this study, we analyzed seafood samples from three fish landing centers and seven retail markets of Mumbai, India for S. enterica contamination. Salmonella was isolated using multiple selective enrichment broths and selective agars, and identified by conventional biochemical tests followed by polymerase chain reaction (PCR).

Results

Of 82 samples of seafood, comprising both finfish and shellfish, Salmonella was detected in 17 (20.7%) finfish samples. None of the shellfish samples (shrimps, clams, and cephalopods) were found to be contaminated with Salmonella. Samples from both landing centers and fish markets, as well as from pelagic and demersal sources, harbored Salmonella. Source-wise analysis showed that 11 of 57 (19.3%) samples from retail fish markets and 6 of 25 (24%) samples from fish landing centers were contaminated with Salmonella.

Conclusions

The study emphasizes the need to implement measures to prevent anthropogenic contamination of coastal waters and improve the hygiene of retail fish markets in Mumbai.

Highlights

Seafood from landing centers and retail markets, as well as from pelagic and demersalhabitats were similarly contaminated with Salmonella. Fish species widely consumed in the region of this study were found highly contaminated with Salmonella.
Printeos v Commission: Importance Of Equal Treatment And Duty To State Reasons In The Calculation Of Fines On Mono-Product Undertakings
Authors: Lourenço Nuno Calaim
Published: March 2020

The General Court (GC), dismissing an appeal from Printeos, held that the application of a non-linear methodology in calculating the amount of fines for different mono-product cartel participants does not, in principle, give rise to a breach of the right to equal treatment and that, by re-imposing a fine on Printeos, the Commission did not breach its right not to be tried twice for the same infringement (the ne bis in idem principle).
Investigating the role of environment in pika (Ochotona) body size patterns across taxonomic levels, space, and time
Authors: Westover Marie L , Smith Felisa A
Published: March 2020

Body size is an important trait in animals because it influences a multitude of additional life history traits. The causal mechanisms underlying body size patterns across spatial, temporal, and taxonomic hierarchies are debated, and of renewed interest in this era of climate change. Here, we tested multiple hypotheses regarding body mass patterns at the intraspecific and interspecific levels. We investigated body size patterns within a climate-sensitive small mammal species, Ochotona princeps (n = 2,873 individuals), across their range with local environmental variables. We also examined body mass of populations over time to determine if body size has evolved in situ in response to environmental change. At the interspecific level we compared the mean mass of 26 pika species (genus Ochotona) to determine if environmental temperatures, food availability, habitat variability, or range area influence body size. We found correlations between temperature, vegetation, and particularly precipitation variables, with body mass within O. princeps, but no linear relationship between body size and any climate or habitat variable for Ochotona species. Body size trends in relation to climate were stronger at the intraspecific than the interspecific level. Our results suggest that body size within O. princeps likely is related to food availability, and that body size evolution is not always a viable response to temperature change. Different mechanisms may be driving body size at the interspecific and intraspecific levels and factors other than environment, such as biotic interactions, may also be influential in determining body size over space and time.
Soil nitrogen availability intensifies negative density-dependent effects in a subtropical forest
Authors: Huang Fengmin , Liang Minxia , Zheng Yi , Liu Xubing , Chen Yuxin , Li Wenbin , Luo Shan , Yu Shixiao
Published: March 2020

Aims

The importance of density-dependent mortality in maintaining tree species diversity is widely accepted. However, density-dependent effects may vary in magnitude and direction with different abiotic conditions in forests. Theoretical predictions surmise that density-dependent effects may vary with soil available nitrogen (AN), but this still needs to be tested.

Methods

We analyzed the density-dependent effects on survival of newly germinated seedlings for 18 common species based on a long-term seedling census across environmental gradients in a subtropical forest. We also conducted a root lesion detection experiment for five species to investigate the potential effects of pathogens on variation in density-dependent disease between rich and poor AN environments.

Important Findings

The seedling dynamics analysis revealed that the strength of density-dependent effects increased with AN, shifting from neutral or positive with low AN to negative with high AN. Three of the five tree species had stronger density-dependent effects on root lesions in rich AN environments than in poor AN environments, which is consistent with the results of a long-term seedling dynamics analysis. We also found higher species diversity in rich AN environments, which may be promoted by the stronger negative density-dependent effects. Both the seedling dynamic analysis and root lesion detection experiment revealed stronger negative density-dependent effects in higher AN environment, resulting from stronger disease pressure by soil pathogens. Our study emphasized the importance of considering context dependence when testing the density dependence hypotheses.
Slower development of lower canopy beans produces better coffee
Authors: Cheng Bing , Smyth Heather E , Furtado Agnelo , Henry Robert J
Published: March 2020

The production of high-quality coffee is being challenged by changing climates in coffee-growing regions. The coffee beans from the upper and lower canopy at different development stages of the same plants were analyzed to investigate the impact of the microenvironment on gene expression and coffee quality. Compared with coffee beans from the upper canopy, lower canopy beans displayed more intense aroma with higher caffeine, trigonelline, and sucrose contents, associated with greater gene expression in the representative metabolic pathways. Global gene expression indicated a longer ripening in the lower canopy, resulting from higher expression of genes relating to growth inhibition and suppression of chlorophyll degradation during early bean ripening. Selection of genotypes or environments that enhance expression of the genes slowing bean development may produce higher quality coffee beans, allowing coffee production in a broader range of available future environments.
SuperCLASS – I. The super cluster assisted shear survey: Project overview and data release 1
Authors: Battye Richard A , Brown Michael L , Casey Caitlin M , Harrison Ian , Jackson Neal J , Smail Ian , Watson Robert A , Hales Christopher A , Manning Sinclaire M , Hung Chao-Ling , Riseley Christopher J , Abdalla Filipe B , Birkinshaw Mark , Demetroullas Constantinos , Chapman Scott , Beswick Robert J , Muxlow Tom W B , Bonaldi Anna , Camera Stefano , Hillier Tom , Kay Scott T , Peters Aaron , Sanders David B , Thomas Daniel B , Thomson A P , Tunbridge Ben , Whittaker Lee ,   (SuperCLASS Collaboration)
Published: March 2020

The SuperCLuster Assisted Shear Survey (SuperCLASS) is a legacy programme using the e-MERLIN interferometric array. The aim is to observe the sky at L-band (1.4 GHz) to a r.m.s. of $7\, \mu {\rm Jy}\,$beam−1 over an area of $\sim 1\, {\rm deg}^2$ centred on the Abell 981 supercluster. The main scientific objectives of the project are: (i) to detect the effects of weak lensing in the radio in preparation for similar measurements with the Square Kilometre Array (SKA); (ii) an extinction free census of star formation and AGN activity out to z ∼ 1. In this paper we give an overview of the project including the science goals and multiwavelength coverage before presenting the first data release. We have analysed around 400 h of e-MERLIN data allowing us to create a Data Release 1 (DR1) mosaic of $\sim 0.26\, {\rm deg}^2$ to the full depth. These observations have been supplemented with complementary radio observations from the Karl G. Jansky Very Large Array (VLA) and optical/near infrared observations taken with the Subaru, Canada-France-Hawaii, and Spitzer Telescopes. The main data product is a catalogue of 887 sources detected by the VLA, of which 395 are detected by e-MERLIN and 197 of these are resolved. We have investigated the size, flux, and spectral index properties of these sources finding them compatible with previous studies. Preliminary photometric redshifts, and an assessment of galaxy shapes measured in the radio data, combined with a radio-optical cross-correlation technique probing cosmic shear in a supercluster environment, are presented in companion papers.
Earth-size planet formation in the habitable zone of circumbinary stars
Authors: Barbosa G O , Winter O C , Amarante A , Izidoro A , Domingos R C , Macau E E N
Published: March 2020

This work investigates the possibility of close binary (CB) star systems having Earth-size planets within their habitable zones (HZs). First, we selected all known CB systems with confirmed planets (totaling 22 systems) to calculate the boundaries of their respective HZs. However, only eight systems had all the data necessary for the computation of HZ. Then, we numerically explored the stability within HZs for each one of the eight systems using test particles. From the results, we selected five systems that have stable regions inside HZs, namely Kepler-34,35,38,413, and 453. For these five cases of systems with stable regions in HZ, we perform a series of numerical simulations for planet formation considering discs composed of planetary embryos and planetesimals, with two distinct density profiles, in addition to the stars and host planets of each system. We found that in the case of the Kepler-34 and 453 systems, no Earth-size planet is formed within HZs. Although planets with Earth-like masses were formed in Kepler-453, they were outside HZ. In contrast, for the Kepler-35 and 38 systems, the results showed that potentially habitable planets are formed in all simulations. In the case of the Kepler-413system, in just one simulation, a terrestrial planet was formed within HZ.
Mid-infrared variability of γ-ray emitting blazars
Authors: Anjum Ayesha , Stalin C S , Rakshit Suvendu , Gudennavar Shivappa B , Durgapal Alok
Published: March 2020

Using data from the Wide-field Infrared Survey Explorer, we studied the mid-infrared (mid-IR) 3.4 μm (W1-band) and 4.6 μm (W2-band) flux variability of γ-ray emitting blazars. Our sample consists of 460 flat spectrum radio quasars (FSRQs) and 575 BL Lacertae (BL Lac) objects. On intraday time-scales, the median amplitude of variability (σm) for FSRQs is 0.04$^{+0.03}_{-0.02}$ and 0.05$^{+0.03}_{-0.02}$ mag in W1 and W2 bands. For BL Lacs, we found median σm in W1(W2) bands of 0.04$^{+0.01}_{-0.02}$ (0.04$^{+0.02}_{-0.02}$) mag. On long time-scales, for FSRQs we found a median σm of 0.44$^{+0.28}_{-0.27}$ and 0.45$^{+0.27}_{-0.27}$ mag in W1 and W2 bands, while for BL Lacs, the median values are 0.21$^{+0.18}_{-0.12}$ and 0.22$^{+0.18}_{-0.11}$ mag in W1 and W2 bands. From statistical tests, we found FSRQs to show larger σm than BL Lacs on both intraday and long time-scales. Among blazars, low synchrotron peaked sources showed larger σm compared to intermediate synchrotron peaked and high synchrotron peaked sources. The larger σm seen in FSRQs relative to BL Lacs on both intraday and long time-scales could be due to them having the most powerful relativistic jets and/or their mid-IR band coinciding with the peak of the electron energy distribution. BL Lacs have low power jets and the observational window too traces the emission from low-energy electrons, thereby leading to low σm. In both FSRQs and BL Lacs predominantly a bluer when brighter behaviour was observed. No correlation is found between σm and black hole mass.
Constraining properties of neutron star merger outflows with radio observations
Authors: Dobie Dougal , Kaplan David L , Hotokezaka Kenta , Murphy Tara , Deller Adam , Hallinan Gregg , Nissanke Samaya
Published: March 2020

The jet opening angle and inclination of GW170817 – the first detected binary neutron star merger – were vital to understand its energetics, relation to short gamma-ray bursts, and refinement of the standard siren-based determination of the Hubble constant, H0. These basic quantities were determined through a combination of the radio light curve and Very Long Baseline Interferometry (VLBI) measurements of proper motion. In this paper, we discuss and quantify the prospects for the use of radio VLBI observations and observations of scintillation-induced variability to measure the source size and proper motion of merger afterglows, and thereby infer properties of the merger including inclination angle, opening angle, and energetics. We show that these techniques are complementary as they probe different parts of the circum-merger density/inclination angle parameter space and different periods of the temporal evolution of the afterglow. We also find that while VLBI observations will be limited to the very closest events it will be possible to detect scintillation for a large fraction of events beyond the range of current gravitational wave detectors. Scintillation will also be detectable with next-generation telescopes such as the Square Kilometre Array, 2000 antenna Deep Synoptic Array, and the next-generation Very Large Array, for a large fraction of events detected with third-generation gravitational wave detectors. Finally, we discuss prospects for the measurement of the H0 with VLBI observations of neutron star mergers and compare this technique to other standard siren methods.
An attempt to constrain Planet Nine’s orbit and position via resonant confinement of distant TNOs
Authors: Downey Brynna G , Morbidelli Alessandro
Published: March 2020

We considered four TNOs on elongated orbits with small semimajor axis uncertainties: Sedna, 2004 VN112, 2012 VP113, and 2000 CR105. We found two sets of simultaneous near commensurabilities for these objects with a putative Planet Nine that are compatible with the current uncertainties in the objects’ orbital periods. We conducted a large number of numerical simulations of quasi-coplanar simulations (i.e. inclinations of Planet Nine and TNOs set to zero but not the giant planets) to find which values of Planet Nine’s mean anomaly and longitude of perihelion could put these objects in stable mean motion resonance (MMR) librations. We found no cases of simultaneous stable librations for multiple TNOs for more than 800 My, with most librations lasting much shorter than this time-scale. The objects 2004 VN112 and 2000 CR105 are the most unstable. Being in an MMR is not a strict requirement for long-term survival in 3D simulations, so our result cannot be used to refute Planet Nine’s existence. Nevertheless, it casts doubt and shows that theoretical attempts to constrain the position of the planet on the sky are not possible.
Effects of rotational disruption on the evolution of grain size distribution in galaxies
Authors: Hirashita Hiroyuki , Hoang Thiem
Published: March 2020

Interstellar dust grains can be spun up by radiative torques, and the resulting centrifugal force may be strong enough to disrupt large dust grains. We examine the effect of this rotational disruption on the evolution of grain size distribution in galaxies. To this goal, we modify our previous model by assuming that rotational disruption is the major small-grain production mechanism. We find that rotational disruption can have a large influence on the evolution of grain size distribution in the following two aspects especially for composites and grain mantles (with tensile strength ∼107   erg cm −3). First, because of the short time-scale of rotational disruption, the small-grain production occurs even in the early phase of galaxy evolution. Therefore, even though stars produce large grains, the abundance of small grains can be large enough to steepen the extinction curve. Secondly, rotational disruption is important in determining the maximum grain radius, which regulates the steepness of the extinction curve. For compact grains with tensile strength ≳109   erg cm −3, the size evolution is significantly affected by rotational disruption only if the radiation field is as strong as (or the dust temperature is as high as) expected for starburst galaxies. For compact grains, rotational disruption predicts that the maximum grain radius becomes less than 0.2 $\rm{\mu m}$ for galaxies with a dust temperature ≳50 K.
The assembly of dusty galaxies at z ≥ 4: statistical properties
Authors: Graziani L , Schneider R , Ginolfi M , Hunt L K , Maio U , Glatzle M , Ciardi B
Published: March 2020

The recent discovery of high-redshift dusty galaxies implies a rapid dust enrichment of their interstellar medium (ISM). To interpret these observations, we run a cosmological simulation in a 30 h−1 cMpc/size volume down to z ≈ 4. We use the hydrodynamical code dustygadget, which accounts for the production of dust by stellar populations and its evolution in the ISM. We find that the cosmic dust density parameter (Ωd) is mainly driven by stellar dust at z ≳ 10, so that mass- and metallicity-dependent yields are required to assess the dust content in the first galaxies. At z ≲ 9, the growth of grains in the ISM of evolved systems [log(M⋆/M⊙) > 8.5] significantly increases their dust mass, in agreement with observations in the redshift range 4 ≲ z < 8. Our simulation shows that the variety of high-redshift galaxies observed with the Atacama Large Millimeter Array can naturally be accounted for by modelling the grain growth time-scale as a function of the physical conditions in the gas cold phase. In addition, the trends of dust-to-metal and dust-to-gas (${\cal D}$) ratios are compatible with the available data. A qualitative investigation of the inhomogeneous dust distribution in a representative massive halo at z ≈ 4 shows that dust is found from the central galaxy up to the closest satellites along polluted filaments with $\rm log({\cal D}) \le -2.4$, but sharply declines at distances d ≳ 30 kpc along many lines of sight, where $\rm log({\cal D}) \lesssim -4.0$.
A systematic analysis of the phase lags associated with the type-C quasi-periodic oscillation in GRS 1915+105
Authors: Zhang Liang , Méndez Mariano , Altamirano Diego , Qu Jinlu , Chen Li , Karpouzas Konstantinos , Belloni Tomaso M , Bu Qingcui , Huang Yue , Ma Xiang , Tao Lian , Wang Yanan
Published: March 2020

We present a systematic analysis of the phase lags associated with the type-C quasi-periodic oscillations (QPOs) in GRS 1915+105 using RXTE data. Our sample comprises 620 RXTE observations with type-C QPOs ranging from ∼0.4 to ∼6.3 Hz. Based on our analysis, we confirm that the QPO phase lags decrease with QPO frequency, and change sign from positive to negative at a QPO frequency of ∼2 Hz. In addition, we find that the slope of this relation is significantly different between QPOs below and above 2 Hz. The relation between the QPO lags and QPO rms can be well fitted with a broken line: as the QPO lags go from negative to positive, the QPO rms first increases, reaching its maximum at around zero lag, and then decreases. The phase-lag behaviour of the subharmonic of the QPO is similar to that of the QPO fundamental, where the subharmonic lags decrease with subharmonic frequency and change sign from positive to negative at a subharmonic frequency of ∼1 Hz; on the contrary, the second harmonic of the QPO shows a quite different phase-lag behaviour, where all the second harmonics show hard lags that remain more or less constant. For both the QPO and its (sub)harmonics, the slope of the lag–energy spectra shows a similar evolution with frequency as the average phase lags. This suggests that the lag–energy spectra drive the average phase lags. We discuss the possibility for the change in lag sign, and the physical origin of the QPO lags.
Discovery of a thermonuclear Type I X-ray burst in infrared: new limits on the orbital period of 4U 1728-34
Authors: Vincentelli F M , Cavecchi Y , Casella P , Migliari S , Altamirano D , Belloni T , Diaz-Trigo M
Published: March 2020

We report the detection of an infrared burst lagging a thermonuclear Type I X-ray burst from the accreting neutron star (NS) 4U 1728-34 (GX 354-0). Observations were performed simultaneously with XMM–Newton (0.7–12 keV), NuSTAR (3–79 keV), and HAWK-I@VLT (2.2 $\, \mu$m). We measure a lag of 4.75 ± 0.5 s between the peaks of the emission in the two bands. Due to the length of the lag and the shape of the IR burst, we found that the most plausible cause for such a large delay is reprocessing of the Type I burst X-rays by the companion star. The inferred distance between the NS and the companion can be used to constrain the orbital period of the system, which we find to be larger than ∼66 min (or even ≳2 h, for a realistic inclination <75°). This is much larger than the current tentatively estimated period of ∼11 min. We discuss the physical implications on the nature of the binary and conclude that most likely the companion of 4U 1728-34 is a helium star.