bluuebunny/crossref_metadata_2025 huggingface dataset:
ТЕХНОЛОГІЇ ФОРМУВАННЯ ДЕМОКРАТИЧНОГО ІМІДЖУ УКРАЇНИ У ВНУТРІШНЬОМУ ТА ЗОВНІШНЬОМУ СЕРЕДОВИЩІ: ПОЛІТИЧНЕ РЕФОРМУВАННЯ
Authors: Petrov Pavlo H.
Published: January 2022

У статті здійснюється аналіз специфіки технологічного формування іміджу України шляхом політичного реформування у внутрішньої та зовнішньої спільноти. Досліджується нормативно-правове трансформування України зі становлення незалежності. Виокремлюються основні нормативні положення, що якісно реалізують процес політичного реформування та підвищення демократичного іміджу України. Аналізуються позитивні та негативні елементи технологічного формування демократичного іміджу України засобами політичного реформування. Наводяться рекомендації щодо підвищення ефективності політичного реформування України у контексті формування якісного демократичного іміджу у внутрішньої та зовнішньої спільнотах.
БІЛОРУСЬ ЯК КЛЮЧОВИЙ ІНСТРУМЕНТ ЗАБЕЗПЕЧЕННЯ ГІБРИДНОЇ СТРАТЕГІЇ РОСІЙСЬКОЇ ФЕДЕРАЦІЇ У ВІЙНІ ПРОТИ УКРАЇНИ ТА У ПРОТИСТОЯННІ З ЄС І НАТО
Authors: Tverdokhlib Yuliia
Published: January 2022

Стаття присвячена аналізу гібридного сценарію Російської Федерації щодо встановлення повного контролю над Республікою Білорусь та використанням останньої у війні проти України та у протистоянні Європейському Союзу та НАТО.
ФІЛОСОФІЯ КУЛЬТУРИ У ГОРИЗОНТІ ФІЛОСОФСЬКОЇ МАЙСТЕРНІ
Authors: Shevtsov Serhii Victorovych
Published: January 2022

Розглядаються філософсько-педагогічні проблеми філософії культури. Мета роботи – артикуляція певних змістовних й методологічних аспектів філософії культури у межах науково-дослідницького проекту філософської майстерні. Надана стисла розмітка філософської майстерні, як комунікативної науково-дослідної лабораторії. Окреслені умови комунікативного повороту у викладанні філософії культури (подолання пасивності сприйняття учбового матеріалу, вихід за межі лекційно-семінарської форми, пріоритет методологічної складової над інформативною, співпраця викладача та студентів тощо). Показані механізми, через які типологія культури стає основою розвитку навичок й вмінь з дескрипції та пояснення. З’ясовані особливості методологічної організації праці у межах онтології культури, як основи розвитку навичок й вмінь за аналітики та герменевтики текстів. Показано, що компаративістика у власній методологічній спрямованості базується на ідеє діалогу культур, являє собою інтегративну частину курсу, яка синкретично поєднує типологічну та онтологічну проблематику культури.
INTERNATIONAL LEGAL SOLUTION TO THE PROBLEMS OF THE ARAL AND CASPIAN SEAS
Authors: Mykytchuk Nataliia
Published: January 2022

he causes and consequences of the drying up of the Aral Sea have been determined. The international initiatives of the leaders of the Central Asian states are considered, the activity of the International Fund for Saving the Aral Sea is analyzed. It was found that the uncertainty of the legal status of the Caspian Sea, the lack of agreement on the distribution of the bottom of the Caspian Sea and the order of subsoil use have become destabilizing factors in shaping the geopolitical situation in Central Asia. The settlement of the conflicting interests of the Caspian states on a bilateral basis in 1998-2014 is analyzed. It is established that the result of international agreements was the Convention on the Legal Status of the Caspian Sea (2018). This agreement formalized the sovereign and exclusive rights of the parties, the collective use of marine resources and the responsibilities of the parties and paved the way for the construction of submarine pipelines, which will enhance the Caspian Sea as one of the key centers of geopolitical and geoeconomic processes. However, the signing of the Convention on the Status of the Caspian Sea did not solve all the existing problems. Regional platforms set up to address the problems of the Aral Sea have proved ineffective and have not improved the environmental situation in the Aral Sea. The region continues to be a zone of global environmental disaster.
As novas tecnologias da informação na educação: desafios, possibilidades e contribuições para ensino e aprendizagem
Authors: Conceição José Luis Monteiro da , Ferreira Fabricio Nicácio
Published: January 2022

No século XIX, o ensino praticado pelos professores era tecnicamente inspirado na educação tradicional. As estratégias didáticas adotadas resumiam-se em aulas expositivas, mantendo-o como detentor do conhecimento e o aluno expectador. Com o passar do tempo, esse cenário foi modificado, principalmente pele a inserção de Tecnologias da Informação e Comunicação (TIC´s) no processo educativo. Contudo, ainda é perceptível a existência de empasses que devem ser superados. Neste sentido, o presente artigo tem como objetivo discutir as barreiras que impedem os professores utilizarem das TIC em suas aulas. Visa também, apresentar as contribuições que elas propiciam tanto para o aluno, quanto para o professor em benefício de uma aprendizagem integral e significativa. Assim, realizou-se um estudo bibliográfico com a sistematização de pesquisas empíricas brasileiras publicadas no período de 2016 a 2021. Constatou-se que existem barreiras que interferem na adoção das TIC no ambiente escolar, a saber: a resistência por parte do docente sobre o uso das ferramentas tecnológicas, equipamentos no ambiente escolar sucateados, falta de investimento em infraestrutura nas escolas, ausência de laboratórios de informática e falta de capacitação docente para usar a tecnologia. No entanto, foi consenso entre 100% dos estudos o quanto as TIC´s contribuem efetivamente para a prática pedagógica do professor e, sobretudo na aprendizagem do aluno.
PHYSICAL DEVELOPMENT AND PHYSICAL FITNESS OF FEMALE STUDENTS FROM THE UNWE’S BASKETBALL GROUPS
Authors: Kasabova L.
Published: January 2022

The dynamic times we live in require that curricula and scales for assessment of physical development and fitness to be updated. This circumstance gave birth to the idea of conducting our study. The research aims to analyze the changes in the characteristics of physical development and physical fitness of UNWE students. The study contingent is 110 students from the UNWE Sports Optional - Basketball groups, of which 46 are under 18, 42 are 18-20, and 22 are over 21. At the beginning and end of the experiment, testing of key indicators of physical development and fitness was conducted. The data obtained were processed by variation analysis. The physical development of female students is the highest growth in the earliest student age. The smallest growth was at the age of 21 years, which should be taken into account in the construction of the educational process and the preparation of curricula for UNWE students. The physical fitness of female students over 21 years of age is marked to a significant decrease.
INFLUENCE OF A TRAINING MODEL FOR THE DEVELOPMENT OF THE SPEED-STRENGHT QUALITIES OF FEMAL STUDENTS FROM THE UNIVERSITY OF NATIONAL AND WORLD ECONOMY PRACTICING BASKETBALL
Authors: Kasabova L.
Published: January 2022

The changes that have occurred as a result of the application of a training model for the development of speed and strength qualities and the improvement of the basketball coordination of movement have been observed. The performance of the model was monitored in 38 students from the basketball study groups divided into two groups [EG] and [KG], after a preliminary test aimed at equalizing the groups at the beginning of the experiment. In the experimental group was applied and tested a model containing complexes of special exercises to develop bounce, speed and increase coordination of movements when performing technical - tactical techniques. At the beginning and end of the experiment, five indicators carrying information about the respective qualities were tested. The results are subjected to mathematical - statistical processing. The speed-strength readiness of the EG students improved in the application of the training model containing sets of exercises with short-term maximum strength loads with weights and multi-jumps.
Alterations in oxytocin and vasopressin in men with problematic pornography use: The role of empathy
Authors: Kor Ariel , Djalovski Amir , Potenza Marc N. , Zagoory-Sharon Orna , Feldman Ruth
Published: January 2022

Background

Addictive behaviors share clinical, genetic, neurobiological and phenomenological parallels with substance addictions. Despite the prevalence of compulsive sexual behaviors, particularly problematic pornography use (PPU), how neuroendocrine systems relate to PPU is not well understood. Preclinical studies demonstrate alterations in oxytocin and arginine vasopressin (AVP) function in animal models of addiction, but no human study has tested their involvement in PPU.

Method

Participants included 122 males; 69 reported PPU, and 53 were demographically-matched participants without PPU. Plasma oxytocin and AVP levels and oxytocin-to-AVP balance were measured at baseline. Salivary oxytocin was assessed at baseline and in response to four videos depicting neutral/positive social encounters. Participants reported on empathy and psychiatric symptoms.

Results

Baseline plasma AVP levels were elevated in men with PPU, and the ratio of oxytocin-to-vasopressin suggested AVP dominance. Men with PPU reacted with greater oxytocin increases to presentation of neutral/positive social stimuli. Decreased empathic tendencies were found in men with PPU, and this reduced empathy mediated links between oxytocin and pornography-related hypersexuality. Structural equation modeling revealed three independent paths to pornography-related hypersexuality; two direct paths via increased AVP and higher psychiatric symptoms and one indirect path from oxytocin to pornography-related hypersexuality mediated by diminished empathy.

Conclusions

Findings are among the first to implicate neuropeptides sustaining mammalian attachment in the pathophysiology of pornography-related hypersexuality and describe a neurobiological mechanism by which oxytocin-AVP systems and psychiatric symptomatology may operate to reduce empathy and lead to pornography-related hypersexuality.
Transorbitomaxillaris percutan endoszkópos gastrostomia
Authors: Pap István , Jakab-Péter Kinga , Uzsaly János , Tóth István , Barabás Márta-Andrea , Fábián György , Lujber László
Published: January 2022

Összefoglaló. Fej-nyaki daganattal diagnosztizált és kezelt
betegeknél a szájon keresztüli táplálás gyakran nem lehetséges vagy nehezítetté
válik a kezelés valamelyik fázisában. A beteg enteralis táplálásának
biztosítására tartós és hatékony megoldást kell nyújtanunk, erre megfelelő
választás lehet a percutan endoszkópos gastrostomia. A fej-nyaki régióban a
daganat elhelyezkedése, kiterjedtsége és a műtétek miatt megváltozott anatómiai
viszonyok sokszor gátat szabnak a gasztroszkóp hagyományos, szájon át történő
sikeres levezetésének, és így különleges megoldásokra lehet szükség.
Közleményünkben egy, a szakirodalomban is ritkán alkalmazott percutan
endoszkópos gastrostomakészítésről számolunk be. A bemutatott esetben egy
kiterjedt, rosszindulatú fej-nyaki daganat miatt totális maxillectomián és
orbitaexenteratión átesett betegben a műtét következtében kialakult
arcdefektuson át történt a gastroscopia és a tápszonda levezetése, ugyanis
komplett szájzár következtében a beteg a táplálkozásra képtelen volt. A fent
említett módszerrel sikerült a beteg hosszú távú enteralis táplálását megoldani
minimálinvazív módon. Az összetett kóros esetek gyakran állítják kihívások elé a
gyakorló klinikust. Esetbemutatásunkkal szeretnénk felhívni a figyelmet a
hagyományos, megszokott módszerek helyett sokszor nagyobb sikerrel alkalmazható,
személyre szabott terápiás lehetőségekre. Orv Hetil. 2022; 163(3): 116–119.

Summary. Peroral, enteral feeding is often impossible in patients
with head and neck cancer. Percutaneous endoscopic gastrostomy is a
well-established, quick, minimally invasive, and safe procedure for providing
long-term enteral feeding. Space-occupying tumour mass and altered anatomy due
to surgery inhibit the gastroscope’s peroral introduction and the feeding tube’s
placement in some instances. Various access routes and modified insertion
techniques are recommended to overcome the feeding tube insertion challenges. We
present a rare case of a 64-year-old head and neck cancer patient who was unable
to eat orally due to trismus and had a facial soft tissue defect following total
maxillectomy and orbital exenteration. A complete oesophago-gastro-duodenoscopy
and feeding tube insertion were performed transfacially. Percutaneous endoscopic
gastrostomy was successful and uneventful via the maxillary and
orbital soft tissue facial defect. No complication was noted, and long-term
enteral feeding of the patient was provided in a minimally invasive way.
Surgeons often face challenging cases when treating patients with head and neck
cancer. The modification of standard procedures is sometimes required to adapt
surgical techniques to the patient’s specific case. Orv Hetil. 2022; 163(3):
116–119.
Arthrogryposis–renalis diszfunkció–cholestasis szindróma
Authors: Mikó Ágnes , Lóth Szendile , Müller Judit , Lotz Bence , Rossitto Patrizio , Szabolcs Andrea , Benyó Gábor , Jávorszky Eszter , Tory Kálmán , Dezsőfi Antal
Published: January 2022

Összefoglaló. Az arthrogryposis–renalis diszfunkció–cholestasis
(ARC) szindróma igen rossz prognózisú autoszomális recesszív kórkép. A három
vezető tünethez társulhat központi idegrendszeri érintettség, siketség,
cardiovascularis anomália (pitvari és kamrai sövényhiány),
thrombocytafunkció-zavar, rekurrens szepszisek, ichthyosis, valamint
súlyfejlődésben való elmaradás. A háromnapos újszülöttet neuromuscularis
betegség gyanúja miatt vettük át a szülészeti intézményből. Fizikális vizsgálat
során pes equinovarust és hypotrophiás küllemet tapasztaltunk. Kéthetes korában
súlyos tubulopathia, valamint cholestasis igazolódott normális
gamma-glutamil-transzferáz-szint mellett. A perifériás vérkenet vizsgálata során
abnormális morfológiájú thrombocyták ábrázolódtak. Súlygyarapodást komplex
felépített enteralis és parenteralis táplálás segítségével sem sikerült elérni.
Három hónapos korára a gyermek súlya 15%-kal a születési súlya alatt volt. A
kórkép szövődményeként ismétlődő bakteriális véráramfertőzés súlyosbította az
állapotát. Az újszülött klinikai képe az ARC-szindrómának felelt meg. A kóroki
gének szekvenálása során a VPS33B-génben homozigóta
c.498+1G>T variáns igazolódott, mely igazolja a betegség fennállását. Orv
Hetil. 2022; 163(2): 74–78.

Summary. Arthrogryposis–renal dysfunction–cholestasis (ARC) syndrome
is an autosomal recessive multisystem disorder that typically presents with
arthrogryposis, renal tubular leak and neonatal cholestatic jaundice. It can be
accompanied by nervous system abnormalities, deafness, structural cardiac
defects, abnormal platelet morphology, recurrent sepsis, ichthyosis and failure
to thrive. The three-day-old neonate was admitted for a suspected neuromuscular
disorder. On examination, clubfoot, jaundice and hypotonia were found.
Laboratory evaluation revealed tubulopathy and cholestasis with normal
gamma-glutamyl transferase level. Peripheral blood smear evaluation revealed
abnormally giant platelets. Despite the combined enteral and parenteral
nutrition, the infant experienced severe failure to thrive. The phenotype of the
presented neonate is consistent with ARC syndrome. Sequencing of the causal
genes revealed a homozygous consensus splice site VPS33B
mutation (c.498+1G>T), confirming the clinical diagnosis. Orv Hetil. 2022;
163(2): 74–78.
ANALISIS KEMAMPUAN LITERASI SAINS FISIKA SISWA SMA PADA MATERI KINEMATIKA GERAK LURUS DI MASA PANDEMI COVID-19
Authors: Mukharomah Farikhatul , Wiyanto Wiyanto , Darma Putra Ngurah Made
Published: January 2022

Pembelajaran daring di masa pandemi Covid-19 yang tidak maksimal memberikan dampak terhadap kemampuan literasi sains, termasuk literasi sains fisika. Terlebih fakta di Indoensia, kemampuan literasi sains siswa masih rendahmenurut hasil PISA. Oleh karena itu, diperlukan upaya untuk meningkatkan kemampuan literasi sains siswa. Tujuan penelitian ini adalah untuk menganalisis kemampuan awal literasi sains fisika siswa kelas X MIPA SMA Negeri 1 Jepara di masa pandemi Covid-19. Penelitian ini termasuk penelitian deskriptif kuantitatif. Sampel penelitian ini adalah 71 siswa kelas X MIPA SMA Negeri 1 Jepara. Data dikumpulkan dengan wawancara dan tes secara online. Domain kemampuan literasi sains yang diukur adalah domain kompetensi. Hasil penelitian menunjukkan bahwa kemampuan literasi sains fisika siswa pada materi kinematika gerak lurus pada domain kompetensi sebesar 57,50% masih dalam kategori pencapaian “rendah”. Oleh sebab itu, kemampuan literasi sains fisika siswa perlu ditingkatkan. Salah satu faktor rendahnya kemampuan literasi sains fisika ini adalah proses pembelajaran daring yang belum menerapkan kegiatan praktikum. Maka dari itu, upaya untuk meningkatkan kemampuan literasi sains fisika tersebut dapat dilakukan dengan cara melakukan kegiatan praktikum berbasis literasi sains secara daring
First ecological report of bat diversity present in Sierra de Navachiste protected area, Sinaloa, Mexico
Authors: Aguilar-Romero R. J. , Escobedo-Bonilla C. M. , Martínez-Álvarez I. G. , Ley-Quiñónez C. P. , Hart C. E. , Zavala-Félix K. A. , Leal-Moreno R. , Suzán G. , Aguirre A. A. , Zavala-Norzagaray A. A.
Published: January 2022

In Mexico, studies on bats have reported the presence of eight families and a total of 140 species, of which seven families and 55 species are reported for the state of Sinaloa. However, the Sierra de Navachiste, México is a natural protected area of state jurisdiction registered as an area subject to Ecological Conservation. studies on bat populations in this area are scarce or nonexistent, resulting in their environmental needs, current threats and the impact they have at population level being unknown. Despite finding a low species richness (five species), the migratory species Leptonycteris yerbabuenae was caught in Sierra de Navachiste. This bat is included on the IUCN red list (International Union for the Conservation of Nature) as a "vulnerable" species, and in Mexico it is listed as "Special protection" species. This bat is considered a keystone mutualist within the ecosystem due to its function as pollinator of the dominant columnar cacti and spreading its seeds though fruit consumption. These activities promote the dispersal of these plants and maintains the structure and health of the ecosystem. Due to the importance of the Sierra Navachiste as a refuge for at least five bat species, including one migratory and protected species, it is necessary to establish a management plan in order to protect the chiroptera community that depends on it.
Blow-up of Solutions of a Logarithmic Viscoelastic Plate Equation with Delay Term
Authors: Yüksekkaya Hazal , Pişkin Erhan
Published: January 2022

In this paper, we consider a logarithmic viscoelastic plate equation with a delay term in a bounded domain. Under suitable conditions, we establish the blow-up of solutions in a finite time. Time delays often seem in thermal, economic phenomena, biological, chemical, physical, electrical
engineering systems, mechanical applications and medicine.
Relation-Theoretic Revised Fuzzy Banach Contraction Principle and Revised Fuzzy Eldestein Contraction Theorem
Authors: Raj A. Murali , Thangathamizh R.
Published: January 2022

In this paper we extend and generalize the classical Banach's contraction principle and Edelstein's contraction theorem on a Revised fuzzy metric spaces endowed with a binary relation.
Fuzzy Metric Space and Sequel of Common Fixed Point Theorem Using Property E.A.
Authors: Sayyed Shoyeb Ali
Published: January 2022

In the present article, proved a common fixed point theorem in fuzzy metric space using property E.A. for a pair of weakly compatible maps.
Agreeing to bind: the case of Russian
Authors: Reuland Eric , Zubkov Peter
Published: January 2022

This contribution offers an analysis of the structural constraints on the interpretation of the Russian anaphoric expressions sebja and svoj. It accounts for a number of intricate binding patterns, such as the ‘animacy effect’ in the case of non-local binding and apparent irregularities in subject orientation and complementarity in local and long-distance binding. We show that these patterns can be accounted for in a unified manner by Multiple Agree-based dependencies established separately for person and number features, assuming the presence of a φ-incomplete number-only probe low in the structure. As a result of the valuation procedure the reflexives end up only partially valued and thus remain distinct from pronominals.
An audit of patients presenting with clinically benign breast disease to the Helen Joseph Hospital Breast Imaging Unit
Authors: Christofides NC , Rubin G , Beim C-A
Published: January 2022

ABSTRACT BACKGROUND: Benign breast pathology is a common presenting complaint, and its assessment is important to characterise not to miss malignant pathology. At Helen Joseph Hospital (HJH), patients are triaged at the breast clinic according to the clinical suspicion of benign versus malignant disease. The patients are assigned a colour label based on their clinical presentation. This triage system affects waiting times between clinical examination and mammography appointments. This study aims to assess the association between clinical examination and the radiological and pathological findings of disorders deemed clinically benign, and to ascertain the spectrum of benign breast disorders encountered at HJH METHOD: A retrospective study of imaging results of patients at HJH presenting as clinically benign breast disorders from January to June 2018 was conducted. Assessed Breast Imaging-Reporting and Data System (BI-RADS) score was noted and if core biopsies were performed, their results and patient demographics were documented RESULTS: Of the 1 263 clinically benign patients presenting from January to June 2018, the radiological assessment was: BI-RADS 1: 158 (12.5%), BI-RADS 2: 685 (54.2%), BI-RADS 3: 292 (23.1%), BI-RADS 4a: 54 (4.3%), BI-RADS 4b: 29 (2.3 %), BI-RADS 4c: 21 (1.7%), BI-RADS 5: 24 (1.9%). There were 133 biopsies (including eight BI-RADS 3 patients), with 46 (3.6%) confirmed malignancies. The combined specificity of mammography and ultrasound was 65.52% (54.56-75.39%) and combined sensitivity 91.30% (79.21-97.58% CONCLUSION: There is a vast spectrum of benign conditions presenting in this population group with only 3.6% confirmed malignancies, confirming an accurate triage system utilised at the breast clinic. Radiological imaging is highly sensitive but less specific, emphasising the triad of clinical, radiological and histological assessment as the gold standard with regard to diagnosis of breast disease Keywords: clinically benign breast disease, breast imaging unit, Helen Joseph Hospital
An inguinal hernia imposter
Authors: Patel RR , Tu S , Plaskett J
Published: January 2022

SUMMARY This is a report of one of the many imposters of an irreducible inguinal hernia, a dermoid cyst. It is a rare entity that should be considered in the differential diagnosis of a groin lump when an atypical clinical presentation or groin examination occurs. Complete excision with histological evaluation remains the mainstay of surgical treatment. Keywords: dermoid cyst, inguinal hernia, inguinal canal, incarcerated, hernia surgery
The correlation between full moon and admission volume for penetrating injuries at a major trauma centre in South Africa
Authors: Kong VY , Keizer AA , Donovan MM , Weale RD , Raj aretnam NS , Bruce JL , Elsabagh A , Clarke DL
Published: January 2022

ABSTRACT BACKGROUND: The possible effect of full moon on admission volume of trauma centres is a well-mentioned phenomenon that has been perpetuated worldwide. We aimed to review the correlation between full moon and admission volume and to interrogate any possible relationship on admission for penetrating trauma METHODS: A retrospective study from 2012 to 2018 at Pietermaritzburg Metropolitan Trauma Service (PMTS), South Africa RESULTS: A total of 8 722 patients were admitted. Eighty-three per cent (7 242/8 722) were male and the mean age was 29 years. The total number of days during the study period was 1 953, 66 of which were 'full moon' (FM) days and 1 887 were 'non-full moon' (NFM) days. There was no significant difference between gender or age distribution. The mean number of admissions per day on FM days compared with NFM days was not significant (4.1 vs 4.5, p = 0.583). A total of 3 332 patients with penetrating trauma were admitted. This constituted 42% (113/271) of admission on FM days and 38% (3 219) on NFM days, which is not statistically significant (p = 0.229). Subgroup analysis did not demonstrate any significant difference between the number of stab wounds - 28% (77/113) vs 25% (2 124/3 219) - or gunshot wounds - 13% (16/113) vs 12% (990/3 219) - between FM and NFM days CONCLUSION: The correlation between full moon and trauma admission is unfound in our setting. The perpetuating notion that 'it must be full moon tonight' is likely to be an urban myth with no scientific evidence for such a claim Keywords: emergency medicine, trauma, epidemiology, full moon, lunar cycle
Biliary tract anatomical variance - the value of MRCP
Authors: Ferreira C , Noel CB
Published: January 2022

SUMMARY Duplication of the common bile duct (CBD) is a rare congenital anomaly of the bile ducts that should be diagnosed prior to surgery in order to optimise management and prevent complications. We report a case of a patient presenting with choledocholithiasis and type Va duplicated extrahepatic bile duct that was missed on ultrasonography. The atypical course prompted further imaging with magnetic resonance cholangiopancreatography (MRCP), which identified the aberrant bile duct and assisted in safe preoperative and operative management. This case highlights the importance of accurate pre-interventional imaging and agrees with the reclassification of duplications of the CBD. Keywords: bile duct, extrahepatic, anomaly, duplicated, injury
The role of surgery in Conn's syndrome -a case of refractory hypertension secondary to an aldosterone secreting adenoma
Authors: Carides MD , Sishuba NT , Bombil I , Christofides C
Published: January 2022

SUMMARY Primary aldosteronism, eponymously known as Conn's syndrome, has recently gained recognition as the most common cause of endocrine hypertension. Unilateral subtypes, such as aldosterone secreting adenomas, are managed surgically and are potentially curable. The background of refractory hypertension and hypokalaemia in a forty-year-old man raised suspicions of Conn's syndrome which was localised to an aldosterone secreting adenoma in the right adrenal gland. The patient underwent a laparoscopic intraperitoneal right adrenalectomy which resulted in normalisation of his plasma aldosterone concentration as well as improved blood pressure control.
Extralevator abdominoperineal excision for low rectal cancer: oncological outcome after five-year follow-up
Authors: Dermanovic A , Radovanovic Z , Lukic D , Duric M , Kresoja M , Golijanin D
Published: January 2022

ABSTRACT BACKGROUND: Extralevator abdominoperineal excision (ELAPE) is a surgical technique that is indicated for low rectal cancer where sphincter preservation is not possible. Compared to conventional abdominoperineal excision major advantages of ELAPE are the risk reduction of intraoperative bowel perforation and positive circumferential margin which lead to a better oncological outcome. The aim of this study was to present our results in ELAPE surgery METHODS: From February 2011 to February 2015, 40 patients underwent surgery for low rectal cancer at the Oncology Institute of Vojvodina. The collected data included sex, age, preoperative staging, neoadjuvant treatment, operative time, rate of intraoperative bowel perforation, rate of positive circumferential resection margins, histopathological analysis, postoperative mortality, tumour, node and metastasis (TNM) classification, local recurrence (LR) rate and presence of distant metastases RESULTS: Positive circumferential margin was found in three (7.5%) patients while eight (20%) patients had intraoperative bowel perforation. LR during follow-up was seen in seven (17.5%) patients, three of them had intraoperative bowel perforation and two patients had positive circumferential margin. The estimated five-year cumulative incidence of LR is 7%. Distant metastases occurred in 18 (45%) patients. The estimated five-year survival rate is 62% CONCLUSION: The study shows satisfactory five-year survival rates of 62% in a highly complex patient group treated by ELAPE procedure Keywords: rectal cancer, extralevator abdominoperineal excision, local recurrence, overall survival
Translation and linguistic validation of the EORTC QLQ-PAN26 questionnaire for assessment of health-related quality of life in patients with pancreatic cancer and chronic pancreatitis into isiXhosa and Afrikaans
Authors: Gqada KJ , Kotze U , Soldati V , Kloppers C , Krige J , Jonas E
Published: January 2022

ABSTRACT BACKGROUND: Health-related quality of life (HRQOL) parameters have become important components in the holistic management of pancreatic ductal adenocarcinoma (PDAC) and are now increasingly incorporated in treatment protocols. The European Organisation for Research and Treatment of Cancer (EORTC) pancreatic cancer specific questionnaire (QLQ-PAN26) has also been validated for chronic pancreatitis (CP). The objective was to translate the EORTC QLQ-PAN26 questionnaire into and validate it for isiXhosa and Afrikaans METHODS: Following the EORTC translation procedure, two forward translations of the English version into isiXhosa and Afrikaans were performed independently by two language practitioners for each language, followed by reconciliation of disagreements. A back translation of the reconciled version into English by a second pair of language practitioners was done. The results of all the steps were summarised with comments in a report for review by the EORTC translation unit. After proofreading by an external proof-reader chosen by the translation unit, pilot testing was performed on a cohort of ten isiXhosa patients and ten Afrikaans patients with PDAC or chronic pancreatitis. Results were summarised in a pilot-testing report, and the final version approved by the translation unit RESULTS: Thirteen patients diagnosed with PDAC and seven with CP were included in the study. The questionnaire was completed electronically (n = 12) or on paper (n = 8). Median age in the isiXhosa group was 53.7 (range 41-63) and in the Afrikaans group 60.9 (range 35-79). Questions 31-54 had a 100% completion rate, while 35% of respondents did not complete Q55 and Q56. Internal consistency was satisfactory in isiXhosa (alpha = 0.88) and Afrikaans (alpha = 0.89 CONCLUSION: The EORTC QLQ-PAN26 used in patients with PDAC and CP has been translated and linguistic validation performed in isiXhosa and Afrikaans. Availability of a questionnaire in patients' mother tongue should increase the validity of results Keywords: health-related quality of life pancreatic ductal adenocarcinoma, questionnaire translation
Colorectal surgical outcomes following implementation of an enhanced recovery after surgery programme in Cape Town
Authors: Oodit R , Constant DA , Maree F , Lorrimer I , Dalwai EK , Moodley J
Published: January 2022

ABSTRACT BACKGROUND: Colorectal surgery is commonly performed for benign and malignant colorectal disease. The aim of this study was to describe length of stay (LOS), complications and its associated factors in patients undergoing elective colorectal surgery following implementation of an enhanced recovery after surgery (ERAS) programme in South Africa (SA METHODS: Socio-demographic, pre- intra- and postoperative clinical details and compliance to the ERAS guidelines were recorded in all patients undergoing colorectal surgery in a private practice in Cape Town, SA. Means and standard deviations or medians and interquartile range (IQR), as appropriate, were used to describe continuous variables and frequencies and percentages for categorical variables. Bivariate and multivariate analyses using linear regression of log transformed LOS and logistic regression for development of complications were performed RESULTS: Between 2015 and 2019, 457 patients had elective colorectal surgical procedures. The median LOS was 5 days (IQR 3-7). Pre- and intraoperative compliance was 92% and 86% respectively. In total, 203 (44%) patients developed 346 complications, of which 61% were minor. On bivariate analysis, increased intraoperative compliance was associated with a significant decrease in LOS (coefficient [ß] = 0.987, 95% confidence interval [CI] 0.984-0.991) and complications (odds ratio [OR] 0.457, 95/5 CI 0.266-0.787). For every additional 30 minutes of theatre time, irrespective of type of procedure, LOS increased by 8% and complications by 12%. On multivariate analysis, laparoscopic compared to open surgery was also associated with a shorter LOS (exp [ß] = 0.667, 95% CI 0.580-0.767 p < 0.001) and reduced complications (OR 0.457, 95% CI 0.266-0.787 CONCLUSION: Our results show that high compliance to the ERAS guidelines is possible in the private sector in SA and that a significant reduction in LOS can be achieved without placing the patient at a higher risk of complications Keywords: colorectal surgery, perioperative care, ERAS, LMIC, surgical checklist
Compliance to the South African ventral hernia guidelines: inaugural results from the HIG(SA) registry
Authors: Gouws J , Nel D , Bougard HC , Koto Z , Oodit R , Kloppers JC
Published: January 2022

ABSTRACT BACKGROUND: The Hernia Interest Group (HIG) of South Africa (SA), following the publication of their inguinal and ventral hernia guidelines (in 2015 and 2016 respectively), developed a hernia registry, the HIG(SA) hernia registry METHODS: A retrospective analysis of the prospectively maintained HIG(SA) hernia registry from 1 February 2019 to 29 February 2020. Compliance to six recommendations made in the HIG(SA) ventral hernia guidelines were assessed in both the public and private healthcare systems RESULTS: Three hundred and fifty-three ventral hernia repair cases were included in the study. Fifty-four per cent were private and 46% were public sector cases. Laparoscopic repair for patients with a BMI > 35 kg/m2 occurred in 38% of eligible cases and a minimum 5 cm of mesh overlap was achieved in 50% of cases. Overall, 80% of elective cases occurred in non-smokers; 97% of the intraperitoneal on-lay mesh (IPOM) repairs used composite mesh; 96% of ventral hernias with defects of larger than 2 cm and 95% of incisional hernias were repaired with mesh. Non-smokers undergoing repair numbered 72% in public and 85% in private practice, p = 0.01 CONCLUSION: Ventral hernia repair practices in SA facilities overall had good compliance to four out of the six HIG(SA) ventral hernia guidelines highlighted for the purposes of this study. The two guidelines that had poor compliance overall were 'laparoscopic repair for patients with a BMI of > 35 kg/m2' and 'ensuring a mesh overlap of 5 cm'. The public sector had higher rates of current smokers undergoing elective ventral hernia repair Keywords: registry, low-middle income countries, ventral hernia, hernia guidelines
Childhood and adolescent trauma in Pietermaritzburg is a neglected sub-epidemic within a larger epidemic and warrants a dedicated service
Authors: Conradie B , Xu W , Kong V , Clarke DL , Bruce JL , Manchev V , Laing GL , Bekker W
Published: January 2022

ABSTRACT BACKGROUND: This study reviews our experience with paediatric trauma to help plan and strengthen ongoing strategies to deal with trauma in our region METHODS: All children and adolescents less than 18 years of age who were admitted to our centre following trauma between December 2012 and October 2020 were reviewed RESULTS: Over the 8-year period, 2 091 children were admitted with trauma to Grey's Hospital. There were 1 479 (71%) male patients, median age: 10 years. One thousand four hundred and fifty-eight (70%) patients were referral from rural regions. In 1 597 (76%) patients, the mechanism of injury was blunt trauma. A total of 387 (19%) patients underwent a surgical intervention, whilst 1 641 (78%) patients were managed non-operatively. In 63 patients, management records were missing. Multiple patients required multiple surgical procedures. A total of 144 patients had a laparotomy, 70 a soft tissue debridement procedure, 40 an orthopaedic procedure, 53 a neurosurgical procedure, which included 37 patients who underwent craniotomy, and 18 patients underwent a fasciotomy for compartment syndrome. There were 82 patients who required miscellaneous procedures. A total of 213 (10%) patients required ICU admission. There were 48 (2.3%) deaths CONCLUSION: The volume of child and adolescent trauma managed is significant and suggests that a dedicated paediatric trauma service in the region is warranted. It is hoped that future partnering with appropriate stakeholders will allow this service to continue to mature and provide leadership in all aspects of care of injured children in the region Keywords: multiple trauma, general surgery, paediatrics
Oral and Oropharyngeal HPV prevalence in South Africa A systematic review and meta-analysis
Authors: Wood Neil , Motloba Pagollang , Makwakwa Louisa Nokukhanya , Bogers John-Paul
Published: January 2022

Prevalence data for HPV infection in the head and neck in Southern African populations is lacking. In addition to cervical cancer, this sexually transmitted oncogenic virus is responsible for a subset of head and neck cancer and is transmitted via oral sexual routes, and through other forms of intimate contact between anatomical sites lined by mucosa. This systematic review and meta-analyses aimed to synthesize data for the prevalence of head and neck HPV infection in South Africa. Original research papers from South Africa reporting on the prevalence of HPV in the head and neck was systematically reviewed using PubMed, Ovid Medline, Embase and the Cochrane Library. A meta-analysis on the prevalence data wasconducted for 16 papers that met the inclusion criteria.
Determinantes del precio de la vivienda nueva en Bogotá para el año 2019: una aproximación a través de un modelo semiparamétrico de regresión espacial
Authors: Toloza-Delgado Jurgen , Melo-Martínez Oscar , Azcarate-Romero Juan
Published: January 2022

Este trabajo toma como punto de partida los recientes avances en el campo de la econometría espacial para desarrollar un modelo de regresión semiparamétrico que permite la inclusión de no linealidades y el modelamiento de la heterogeneidad espacial a través de una función bidimensional que depende de las coordenadas geográficas. La metodología se aplica en un modelo hedónico para el precio de la vivienda nueva en Bogotá donde se obtiene un ajuste destacable, en términos del error cuadrático medio y el R2. El resultado empírico muestra que el estrato, la condición de entrega y el estado constructivo afectan el precio de manera lineal, mientras que el área, y las distancias a parques, vías y estaciones de Transmilenio presentan resultados no lineales; además se logró modelar la tendencia espacial que representa la ubicación sobre el valor de la vivienda, evidenciando un incremento hacia el nororiente de la ciudad. Así, se concluye que el modelo estimado permite medir de manera flexible la relación entre las variables explicativas y la dependiente, estableciéndose como una buena alternativa para entender la formación de los precios en el mercado inmobiliario.
A Generalized of Sλ-I-Convergence of Complex Uncertain Double Sequences
Authors: Granados Carlos
Published: January 2022

In this paper, we introduce the λI2 -statistically convergence sequence concepts which are namely λI2 -statistically convergence almost surely (Sλ(I2) a.s.), λI2 -statistically convergence in measure, λI2 -statistically convergence in mean, λI2 -statistically convergence in distribution and λI2 -statistically convergence uniformly almost surely (Sλ(I2) u.a.s.). Additionally, decomposition theorems and relationships among them are presented, further, when reciprocal of one theorem is not satisfied, an counterexample is shown to support the result.
Lie Algebra Representation, Conservation Laws and Some Invariant Solutions for a Generalized Emden-Fowler Equation
Authors: Loaiza Ossa Gabriel Ignacio , Acevedo-Agudelo Yeisson , Londoño-Duque Oscar , García Hernández Danilo A.
Published: January 2022

All generators of the optimal algebra associated with a generalization of the Endem-Fowler equation are showed; some of them allow to give invariant solutions. Variational symmetries and the respective conservation laws are also showed. Finally, a representation of Lie symmetry algebra is showed by groups of matrices.
Protocols from: Evolutionary analyses of visual opsin genes in frogs and toads: diversity, duplication, and positive selection v1
Authors: K Schott Ryan , Perez Leah , A Kwiatkowski Matthew , Imhoff Vance , Gumm Jennifer
Published: January 2022

Protocols used to extra mRNA from frog retina, create cDNA libraries, and prepare sampled for sequence at the UT core facility under standard protocols.
[RETRACTED] Power CBD Gummies Formula - Clinically Approved? v1
Authors: CBD Gummies Power
Published: January 2022

[RETRACTED]

https://www.mynewsdesk.com/iexponet/pressreleases/power-cbd-gummy-bears-reviews-uk-and-canada-dragons-den-new-elite-power-cbd-gummies-uk-2022-3152973
Senior Citizens during COVID-19 Crisis in the Philippines: Enabling Laws, Current Issues, and Shared Efforts
Authors: Cahapay Michael
Published: January 2022

While COVID-19 affects all ages, there is an unheard side of a vulnerable group of older people across the globe amid the current crisis. This article discusses the condition of senior citizens in the Philippines during the COVID-19 crisis. The review showed that various enabling laws have been enacted to secure the welfare of senior citizens. However, the current crisis revealed issues such as deprivation of income sources, inaccessibility to essential needs, inadequate physical space, and unspoken negative perceptions, which all greatly affect the senior citizens. Thus, to implement the laws and solve the issues, shared efforts should focus to improve social pension payout, guidelines for mobility, different approaches of remote access to essential goods and services, and meaningful internet connectivity in the context of senior citizens.
THE SOURCES FOR FINANCING THE ACCOMODATION SUPPORT IN THE ARMED FORCES OF UKRAINE
Authors:   Taras Shevchenko national University of Kyiv, Gorodianska L. , Tsiukalo L. ,   Taras Shevchenko national University of Kyiv
Published: January 2022

The article presents the qualification of types of accommodation support in the Armed Forces of Ukraine (AFU) in accordance to which the military personnel and their family members are to be supported by newly built accommodation, liberated accommodation, acquired accommodation, service accommodation or a monetary compensation for a premise fit for living. The essence of the financial mechanism of accommodation support in the Armed Forces of Ukraine has been analyzed, which is basically comprised of the funds of the state budget according to the types of generic and special funds. It has been demonstrated that the existing financial mechanism is not perfect, limited in resources accompanied by a large number of bureaucratic obstacles, does not satisfy the modern request for accommodation support within the AFU. According to date provided at the 1-st of January 2021 the overall amount of military personnel accountable for accommodation is at 47,2 thousand, whilst at the same time in the years 2020 and 2021 at the costs of the budget it is only possible to build 4000 apartments a year, which is obviously not sufficient to meet the requirements of the Armed Forces of Ukraine as such. The main reason for the insufficient support of military personnel in terms of accommodation are the limited financial resources that are available to build or to buy (accommodation). Following the detailed analyses of the budget expenditures for the finance support in terms of the program of construction (acquiring) accommodation for military personnel in the years 2011-2020 it has been stipulated, that even the assets of the special fund have not been used completely in the course of the years 2011-2017 and the level of using the budget assets for the accommodation support within the AFU in an overall perspective was within the framework of 27-81 %. It has also been pointed out that the reason for the incomplete using of the budget assets is the systematic delay of approval of the passports of the budget approval of construction (acquiring) accommodation for servicemen. The article suggests the introduction of innovative approaches to support the military personnel with accommodation, namely mortgage lending, financial leasing and investment for housing construction on land plots of the Ministry of Defense of Ukraine. It is also suggested to implement the experience of NATO member state countries that happen to present service premises to military personnel situated on the territory of the unit (garrison) for temporary use, presenting monetary support to hire accommodation, interest-free loans or loans on preferential terms for the purchase or construction of accommodation.
FORMS OF PUBLIC ADMINISTRATION OF TRAINING WITH HIGHER MILITARY EDUCATION FOR THE ARMED FORCES OF UKRAINE
Authors:   Interregional Academy of Personnel Management, Kyiv, Ziborieva O.
Published: January 2022

The purpose of this article is to define the concept and types of forms of public administration for training personnel with higher military education for the Armed Forces of Ukraine. The article analyzes theoretical approaches to the problem of the essence of the forms of public administration. The work highlights the most important features of these forms. The definition of the forms of public administration of personnel training with higher military education for the Armed Forces of Ukraine has been formulated: these are ways of external expression of the achievement of the goals set for the subjects of public administration in this area, carried out by legal and extra-legal (organizational) methods. Taking into account the principle of differentiation by nature and legal nature, it is proposed to divide such forms into four main types: a) rulemaking activities aimed at establishing and specifying the rights, duties and responsibilities of the subjects of the educational process in higher military educational institutions and military educational units of higher educational institutions; b) the publication of executive and administrative and individual legal acts; c) implementation of legally significant actions with the publication of an official document; d) the implementation of interim actions necessary to support the training of personnel with higher military education for the Armed Forces of Ukraine (this includes a wide range of activities related to organizational, managerial, informational, material and technical, personnel, psychological and other types of training for officer personnel). The article substantiates that the forms of public administration of training personnel with higher military education for the Armed Forces of Ukraine are an integral part of the conceptual apparatus of public administration in the security and defense sector. The ontological nature of the studied forms of public administration is due to the need for the practical implementation of legal prescriptions at the legal and individual level to achieve the goals of legal regulation (ensuring the defense capability of the state by training the required number of officers who have the necessary knowledge, skills, skills and personal qualities).