bluuebunny/crossref_metadata_2025 huggingface dataset:
KLASIFIKASI KODE MUTU KAYU PROVINSI SULAWESI SELATAN
Authors: Khairil Khairil
Published: April 2023

ABSTRACT Since wood regulations were revised in 2002, the strength classes of wood are no longer known as class I, II, III, IV and V but known as quality code. The highest quality code is E26 and the smallest is E10. With these changes, it is very possible to confuse the community, especially in the province of South Sulawesi in choosing the type of wood that will be used for construction. This study aims to classify the wood quality code in the province of South Sulawesi based on PKKI NI-5 2002.The study begins by choosing the woods in South Sulawesi to be testing the water content and density of that woods. The result of the tested are used to calculate flexural modulus of elasticity as a basis in determining the wood quality code. The result showed that from 18 kinds of wood studied, twelve kinds of wood have a quality code from E9 to E15 and another six do not have quality code. The six types of wood do not have quality code because the flexural modulus of elasticity of that wood less than 9000 MPa where that value is not classified in PKKI NI-5 2002.Keywords: density, quality code of wood, wood in South Sulawesi, water content, ABSTRAK  Sejak peraturan kayu direvisi pada tahun 2002,penggolongan kelas kuat kayu tidak lagi dikenal sebagai kelas kuat I, II, III, IV dan V namun dikenal dengan istilah kode mutu. Kode mutu terbesar adalah E26 dan yang terkecil E10. Dengan perubahan tersebut, makasangat mungkin dapat membingungkan masyarakat khususnya di provinsi sulawesi selatan dalam memilih jenis kayu yang akan digunakan untuk keperluan konstruksi.Penelitian ini bertujuanuntuk mengklasifikasikan kode mutu kayu yang beredar di provinsi Sulawesi Selatan berdasarkan PKKI NI-5 2002. Penelitian diawali dengan memilih jenis kayu yang beredar di provinsi Sulawesi Selatan dan selanjutnya dilakukan pengujian kadar air dan kerapatan kayu  tersebut untuk digunakan dalam menentukan nilai modulus elastisitas lentur. Dengan nilai modulus elastisitas lentur yang tersebut, maka kode mutu kayu dapat ditentukan. Hasil penelitian memperlihatkan bahwa dari 18 belas jenis kayu yang diuji,  dua belas jenis kayu memiliki kode mutu yaitu E9sampai E15 dan enam jenis kayu yang lain tidak memiliki kode mutu kayu. Keenam jenis kayu tersebut tidak memiliki kode mutu karena nilai modulus elastisas lenturnya lebih kecil dari 9000 MPa dimana nilai modulus elastisitas lentur tersebut tidak di klasifikasikan dalam PKKI NI-5 2002.Kata kunci: kerapatan, kode mutu kayu, kayu provinsi Sulawesi Selatan, kadar air
Clinical conference as an educational technology for training residents in therapeutic specialties
Authors: Ponomareva E. Yu. , Rebrov A. P.
Published: April 2023

The article discusses the concept and educational role of the clinical conference in the preparation of residents of therapeutic specialties at the Department of Hospital Therapy. The purpose of holding a clinical conference of residents is to improve professional and universal competencies and develop clinical thinking in future therapists in the process of teaching hospital therapy. The authors consider the clinical conference as an effective form of educational process that combines students' independent activities, interaction with the teacher, and the formation of basic skills for future medical practice.
Features of development, the possibility of prevention and treatment of atrial fibrillation in patients with diabetes mellitus
Authors: Kanorskii S. G. , Kovalenko Yu. S.
Published: April 2023

Diabetes mellitus (DM) is one of the strongest independent risk factors for the development of atrial fibrillation (AF). Their combination is increasingly common, creating a high risk of complications and poor outcome in patients. A search and analysis of 8907 literature sources from the Scopus, Web of Science, PubMed/MedLine, The CochraneLibrary databases was carried out for the keywords "diabetes mellitus", "atrial fibrillation", "glycemic control", "hypoglycemic therapy". The review presents current ideas about the mechanisms underlying the development of AF in DM, as well as the effect of certain classes of hypoglycemic and other drugs on the risk of AF, some features of the treatment of AF in combination with DM.
The Frequency and the character of bacterial infection in patients with COVID-19
Authors: Karoli N. A. , Rebrov A. P.
Published: April 2023

The first human cases of new coronavirus (COVID-19), for the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), were in Wuhan, in December 2019. By June 2022 there had been more than 500 million with confirmed cases of new coronavirus and over 5 million lives lost to the disease. During the earlier SARS-CoV-1 and MERSCoV epidemics, patients often developed bacterial coinfections and had a higher mortality rate. The aim of this work is to summarize the results of a study of the frequency and nature of bacterial infection in patients with COVID-19. Various studies was been in USA and countries of Asia and Europe show conflicting results regarding the prevalence of secondary bacterial infections in patients with COVID-19, from 1% to 50%. Bacterial co-infection is relatively infrequent in hospitalized patients with COVID-19. Risk factors of bacterial infections in patients with COVID-19 are more 60 years old, prolonged hospital length of stay, reanimation unit admission (severe disease COVID-19), chronic bacterial infection in anamnesis, immunosuppression therapy. The most common bacterial microorganisms identified in patients with infection of the lower respiratory tract, who hospital length of stay less than 48 hours are Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae. In patients, who hospital length of stay more than 48 hours the main pathogens are P. aeruginosa, Klebsiella spp., S. aureus. The data obtained indicate a low frequency of bacterial infections in patients hospitalized for COVID-19. Early infections are quite rare, more often bacterial infections are secondary and develop after 48 hours of the patient's stay in the hospital. The causative agents of early and late infections are different. Most often, an infection of the respiratory tract is noted, less often — the urinary system and bacterial infections of other localization.
Pharmacovigilance: focus on the analysis of spontaneous reports of adverse drug reactions
Authors: Litvinenko T. S. , Polinskaya T. A. , Shishov M. A. , Safronenko A. V. , Gantsgorn E. V.
Published: April 2023

Objective: using the example of data for 2019–2020 in the Rostov region, to analyze the characteristics of spontaneous reports (SR) of adverse drug reactions (ADRs), as well as to assess their correlation with the individual characteristics of patients and the drugs used. Materials and methods: The object of a retrospective descriptive study was 234 SR about ADRs registered in the Rostov region in 2019-2020. Results: highest number of SR about ADRs in 2019–2020 were associated with drugs from the group "Nervous system, "Alimentary tract and inclusion metabolism" and "Antineoplastic and immunomodulators". In 2019, as well as in 2020, there was a statistically significant correlation between the indicators of the drug group and the type about ADRs, the age of the patient and the outcome of the developed ADRs. In addition, in females, a significant relationship was established between the criterion for the severity about ADRs and its outcome. Conclusions: the results obtained during the implementation of this study include the identification of common values and prerequisites for the development about ADRs in 2019 and 2020, and therefore can be taken into account when assessing a risk-based algorithm for the exclusion and emergency of identifying ADRs. This, in turn, inevitably constitutes and personalizes the choice of pharmacotherapy, balanced in terms of "efficacy-safety".
Dynamics of matrix metalloproteinase 9 in comorbid patients who had myocardial infarction with ST elevation
Authors: Syroedov V. A. , Pirozhenko A. A. , Barkova K. V. , Simkina A. A. , Khaisheva L. A. , Shlyk S. V.
Published: April 2023

Aim. The aim of the work was to study for three years the dynamics of matrix metalloproteinase 9 in patients with comorbid pathology who had suffered a myocardial infarction with ST segment elevation. Materials and methods. The study included patients of both sexes older than 18 years. All of them signed an informed consent for participation in the study. The inclusion criteria, in addition to signing informed consent for participation in the study, were acute myocardial infarction with ST elevation (STEMI), PCI and implantation of 1-2 stents into the left coronary artery, the presence of hypertension, type 2 diabetes melitus. Patients younger than 18 years and older than 80 years with type 1 diabetes mellitus, the presence of oncological diseases at the time of the study or in the anamnesis, chronic obstructive pulmonary disease, chronic viral infections were not included. All diagnoses were established according current clinical recommendations. The patients were divided into two groups. The first group included patients with arterial hypertension and type 2 diabetes mellitus, the second group included patients who had suffered acute myocardial infarction with ST segment elevation, who had arterial hypertension and type 2 diabetes mellitus. Serum was used to assess the content of matrix metalloproteinase 9. A standard test kit was used ("Cloud-Clone Corp.", China) in accordance with the instructions. The calculations were carried out using Excel spreadsheets and the statistical software package Statistica 10 (StatSoftInc.) USA. Results. When studying the level of metalloproteinase 9 for 3 years in patients who had suffered a myocardial infarction, it was found that the level of MMP-9 was statistically significantly higher in patients at the time of hospitalization, then decreased by the first year after the index event and became comparable with patients who did not have MI. After 36 months from the start of the study, patients who had suffered a myocardial infarction had statistically significantly higher levels of matrix metalloproteinase 9, compared with their values by the end of the first year, however, these data are comparable to the level of MMP-9 in patients of the first group. The level of MMP-9 in the first group is comparable at all time stages of observation. Conclusion. The inflammatory marker MMP-9, under certain conditions, can serve as a good predictor for predicting fatal outcomes and repeated AMI in patients who have undergone MI.
Lipid-lowering therapy in patients with arterial hypertension with concomitant chronic obstructive pulmonary disease
Authors: Grigoryeva N. U. , Petrova M. O. , Blokhina E. I.
Published: April 2023

Оbjective: in order to evaluate the effects (lipid-lowering, the effect on the endothelial function and oxidative stress) of pitavastatin at a dose of 4 mg in patients with dyslipidemia, arterial hypertension (AH) and chronic obstructive pulmonary disease (COPD) at baseline, after 4 weeks and 12 months of treatment.Material and methods:the prospective study included 33 patients (mean age 60 [54;61] years) with AH, COPD and dyslipidemia. Laboratory examination consisted in determining the lipid spectrum, the level of lipid peroxidation products, creatinine, bilirubin, alanine aminotransferase, aspartate aminotransferase. The endothelium’s function was performed by the test with the endothelium-dependent vasodilation. We prescribed Pitavastatin (4 mg, Livazo, Recordati, Ireland) as a lipid-lowering therapy. After 12 months, the atherosclerotic plaques (AP) in the vessel was seen by the ultrasound duplex scanning of carotid arteries.Results: after 4 weeks of treatment with pitavastatin (4 mg), there was a decrease in total cholesterol — 26%, low-density lipoprotein (LDL) — 33%, triglycerides (TG) — 19%, high-density lipoprotein was increased by 18%. There was an improvement in endothelial dysfunction and oxidative stress. There were no side effects in patients.Conclusion: correction of lipid metabolism disorders in AH patients with COPD by prescribing pitavastatin (4 mg) can reduce total cholesterol, LDL and TG, can positively affect endothelial function and lipid peroxidation processes. Therapy with pitavastatin (4 mg) in patients with dyslipidemia, AH and COPD is safe. It is noted the regression of AP after 12 months of regular intake of pitavastatin at a dose of 4 mg.
Representation Learning for Texts and Graphs
Authors: Galke Lukas Paul Achatius
Published: April 2023

[...] This thesis is situated between natural language processing and graph representation learning and investigates selected connections. First, we introduce matrix embeddings as an efficient text representation
sensitive to word order. [...] Experiments with ten linguistic probing tasks, 11 supervised, and five unsupervised downstream tasks reveal that vector and matrix embeddings have complementary strengths and that a
jointly trained hybrid model outperforms both. Second, a popular pretrained language model, BERT, is distilled into matrix embeddings. [...] The results on the GLUE benchmark show that these models are competitive
with other recent contextualized language models while being more efficient in time and space. Third, we compare three model types for text classification: bag-of-words, sequence-, and graph-based models. Experiments
on five datasets show that, surprisingly, a wide multilayer perceptron on top of a bag-of-words representation is competitive with recent graph-based approaches, questioning the necessity of graphs synthesized
from the text. [...] Fourth, we investigate the connection between text and graph data in document-based recommender systems for citations and subject labels. Experiments on six datasets show that the title as side
information improves the performance of autoencoder models. [...] We find that the meaning of item co-occurrence is crucial for the choice of input modalities and an appropriate model. Fifth, we introduce a generic
framework for lifelong learning on evolving graphs in which new nodes, edges, and classes appear over time. [...] The results show that by reusing previous parameters in incremental training, it is possible to employ
smaller history sizes with only a slight decrease in accuracy compared to training with complete history. Moreover, weighting the binary cross-entropy loss function is crucial to mitigate the problem of class imbalance
when detecting newly emerging classes. [...]
Development of a Corpus Annotated With Mentions of Pain in Mental Health Records: Natural Language Processing Approach
Authors: Chaturvedi Jaya , Chance Natalia , Mirza Luwaiza , Vernugopan Veshalee , Velupillai Sumithra , Stewart Robert , Roberts Angus
Published: April 2023

Background

Pain is a widespread issue, with 20% of adults (1 in 5) experiencing it globally. A strong association has been demonstrated between pain and mental health conditions, and this association is known to exacerbate disability and impairment. Pain is also known to be strongly related to emotions, which can lead to damaging consequences. As pain is a common reason for people to access health care facilities, electronic health records (EHRs) are a potential source of information on this pain. Mental health EHRs could be particularly beneficial since they can show the overlap of pain with mental health. Most mental health EHRs contain the majority of their information within the free-text sections of the records. However, it is challenging to extract information from free text. Natural language processing (NLP) methods are therefore required to extract this information from the text.

Objective

This research describes the development of a corpus of manually labeled mentions of pain and pain-related entities from the documents of a mental health EHR database, for use in the development and evaluation of future NLP methods.

Methods

The EHR database used, Clinical Record Interactive Search, consists of anonymized patient records from The South London and Maudsley National Health Service Foundation Trust in the United Kingdom. The corpus was developed through a process of manual annotation where pain mentions were marked as relevant (ie, referring to physical pain afflicting the patient), negated (ie, indicating absence of pain), or not relevant (ie, referring to pain affecting someone other than the patient, or metaphorical and hypothetical mentions). Relevant mentions were also annotated with additional attributes such as anatomical location affected by pain, pain character, and pain management measures, if mentioned.

Results

A total of 5644 annotations were collected from 1985 documents (723 patients). Over 70% (n=4028) of the mentions found within the documents were annotated as relevant, and about half of these mentions also included the anatomical location affected by the pain. The most common pain character was chronic pain, and the most commonly mentioned anatomical location was the chest. Most annotations (n=1857, 33%) were from patients who had a primary diagnosis of mood disorders (International Classification of Diseases—10th edition, chapter F30-39).

Conclusions

This research has helped better understand how pain is mentioned within the context of mental health EHRs and provided insight into the kind of information that is typically mentioned around pain in such a data source. In future work, the extracted information will be used to develop and evaluate a machine learning–based NLP application to automatically extract relevant pain information from EHR databases.
Disaster Management of Archives in Indonesia: A Systematic Literature Review
Authors: Jalinur Jalinur , Rahmi Rahmi
Published: April 2023

Archives are vital assets to organizations, communities and individuals. Recovering archives from natural and human-made disasters requires careful handling. Governments, agencies, and the private sector must plan and prepare for archive rescue management, the main objective of which is the long-term preservation of documents and archives. This study aims to determine models of disaster affected archive management and to assess challenges to managing disasters in archives in Indonesia by performing a systematic literature review of journal articles published from 2015 to 2020. The results show that the selected journal articles primarily focused on disaster prevention, while disaster recovery was not widely discussed in journal articles from Indonesia. This research examines the suitability of models presented in the literature to manage and rescue archives relative to Indonesia’s rules and existing models and methods.
Konsepsi Pusat Studi Arsip Kedirgantaraan Indonesia: Sebuah Kajian Pendahuluan
Authors: Bawono Harry
Published: April 2023

There are two primary problems of aviation and aerospace governance in Indonesia, the lack of documentation tradition and the lack of passion for research in the aviation and aerospace field. Concerning those issues, the archivistics perspective could effectively contribute to tackling those problems. The research aims to describe the concept of the center for the study of the Indonesian aviation and aerospace archives. In archive management, aviation and aerospace archives can be categorized as special collections. Used the literature review method, this research found that the concept of the center for the study of the Indonesian aviation and aerospace archives is used by the national archival institution either to fulfill one of the archives administration objectives and also to help the aviation and aerospace community tackle the problems of aerospace governance in Indonesia. As preliminary research, this research needs further development by the next researcher so that the concepts of the center for the study of the Indonesian aviation and aerospace archives easier to translate at the policy level.
Strategi Peningkatan Aksesibilitas Arsip Statis Sebagai Informasi Publik Pada Lembaga Kearsipan di Era Keterbukaan Informasi
Authors: Mufidati Tri Yekti , Wijayanti Luki
Published: April 2023

Accessibility of archival information in the era of information disclosure is marked by the development of technology and information, which is a challenge for archival institutions in meeting community needs for historical information sourced from archives. As a public information institution, archival institutions must transform in carrying out their functions and duties in order to provide excellent service to the public using static archives. However, in practice, efforts to realize the accessibility of static archives as a source of public information at archival institutions (LK) have experienced problems related to the deposit of archives as a collective memory. This is caused by two things, namely that there are still many archive creators who have not submitted static archives to le, and the limited understanding and archival outreach of the public. This study describes how to improve the accessibility of archives as public information on LK in the era of information disclosure, using a qualitative approach and literature study methods. The results of this study indicate that the low accessibility of archives is caused by the lack of optimal archival management development, the low availability of archives as a result of the low quality of archive management in LK, and the lack of public understanding of the role of LK as a repository of historical information.
Peran Penataan Arsip Dinamis Inaktif Dalam Mendukung Aktivitas Organisasi Di Universitas Islam Kadiri (UNISKA) Kediri
Authors: Permadani Sonia Putri , Waluyo Waluyo
Published: April 2023

Suatu organisasi yang tentu saja bekerja, baik publik maupun swasta, akan menghasilkan arsip. Arsip adalah catatan kegiatan atau bukti kegiatan organisasi dalam menjalankan fungsi. Secara fungsional, arsip dikategorikan menjadi dua jenis, yaitu arsip dan arsip statis. Catatan dinamis adalah file yang langsung digunakan oleh organisasi yang dibuat untuk kepentingan operasional organisasi. Sedangkan arsip statis adalah arsip yang pada umumnya tidak lagi digunakan dalam operasional organisasi pencipta tetapi karena memiliki nilai sejarah dan nilai maka arsip tersebut dilestarikan sebagai arsip permanen. Sebagai arsip dinamis, keberadaan arsip yang tidak aktif harus dijaga sesuai aturan arsip karena sifatnya dinamis berarti arsip masih dibutuhkan dalam kegiatan organisasi.Pada umumnya karena frekuensi penggunaan yang menurun menyebabkan arsip yang tidak aktif menjadi terabaikan bahkan tidak terkelola. Dalam kondisi demikian, arsip pada umumnya dalam keadaan tidak beraturan. Penelitian ini berusaha untuk menggali kondisi arsip yang tidak aktif dan memanfaatkan dalam kegiatan organisasi di Universitas Islam Kadiri (UNISKA) Kediri. Masalah yang diangkat dari penelitian ini adalah bagaimana penataan arsip inaktif dan bagaimana peran arsip inaktif dalam mendukung kegiatan organisasi, serta kendala apa saja yang dihadapi dalam proses penataan arsip inaktif di Universitas Islam Kadiri (UNISKA) Kediri. Penelitian ini bersifat deskriptif-analitis dengan metode kualitatif.Pengumpulan data penelitian ini meliputi observasi, wawancara, dan studi pustaka dokumen. Kesimpulan utama dari penelitian ini adalah kondisi arsip di Universitas Islam Kadiri (UNISKA) Kediri masih tercampur antara arsip dengan non arsip dan arsip tidak aktif dalam kondisi tidak beraturan.
KOMUNIKASI ANTARBUDAYA DALAM KONFLIK DI MEDIA SOSIAL (CONTENT ANALYSIS KONFLIK OVERSTAY KRISTEN GRAY DI TWITTER)
Authors: Wicaksono Dimas Satriawan Lambang , Fauziah Farah Fattatin , Adinta Ulima Nabila , Sadasri Lidwina Mutia
Published: April 2023

Social media has become a place for various limitless interactions, including conflict interaction. This research is intended to discover the face management of individuals with different cultural backgrounds in intercultural conflict situations on social media. One of the issues that can be studied using the concept of face negotiation theory is the case of Kristen Gray’s overstay, which was discussed for several days on Twitter. Therefore, three research questions emerge: (1) how is face management between Indonesian citizens and Black Americans in the intercultural conflict "Kristen Gray" on Twitter in the period of January 17-20, 2021? (2) when compared to Ting-Toomey's assumption, is there any change in face management in Indonesian and Black American individuals? (3) why did face management changes occur? Content Analysis is used as a primary method. There are several findings in this research: individualistic face management is shown by both conflicting actors, shifting in Indonesian’s netizen face management that analyzed using the role of social media, and absence of Black’s face management shifting is analyzed using community perspective.
Skin Lesion Segmentation and Classification Using Deep Learning
Authors: K S Mr. Gokul , S T Ms. Pumenitha , Vasanth S V Mr. Hema
Published: April 2023

Abstract: Classification of skin lesions has recently received a lot of attention. Due to the high degree of similarity between the skin lesions, physicians frequently take a long time to examine them. A deep learning-based automated classification system can help doctors identify the type of skin lesion and improve the patient's health. With the development of deep learning architecture, the classification of skin lesions has emerged as a popular area of research. In this research, we present a method to use segmentation and techniques like Averaging of Deep Learning Architectures and classify skin lesions. We evaluated the proposal using a large dataset: HAM 10000. Our numerical results using VGGNet and ResNet using good results on the mentioned dataset.
A Detailed Study of Winding Up of a Company
Authors: Rastogi Nimisha , Dixit Aastha
Published: April 2023

Abstract: This research provides a brief overview of the process of winding up a company, which involves the formal closure of a business entity through the sale of assets, settlement of liabilities, and distribution of proceeds to creditors and shareholders. The winding-up process can be either voluntary or compulsory, and requires compliance with legal and regulatory requirements. Factors affecting the duration of the process include the company's structure and outstanding debts.
Elektromanyetik Radyasyonun (2.45 GHz) Lenfosit DNA Hasarına ve Hematolojik Parametrelere Etkisi: Vitamin C'nin Koruyucu Rolü
Authors: KAVRIK Oğuzhan , SAYGIN Mustafa , ASLANKOÇ Rahime , GÜMRAL Nurhan , AŞCI Halil , CANKARA Fatma Nihan
Published: April 2023

Amaç: Bu çalışmanın amacı, kanda hematolojik ve biyokimyasal değişikliklere neden olabilen 2.45 GHz elektromanyetik radyasyonun (EMR) etkilerini araştırmaktır. EMR maruziyetinin etkilerine karşı koruyucu özelliği olan Vitamin C'yi (Vit C) tercih ettik.
Materyal-Metot: Bu çalışma için 18 dişi Sprague Dawley sıçanı rastgele her birinde altı hayvan bulunan üç gruba ayrıldı: Kontrol, EMR ve EMR+Vit C grupları. Kontrol grubu: gavaj ile 30 gün boyunca 0.1 ml/gün salin; EMR grubu: EMR, 30 gün boyunca 1 saat/gün; EMR+Vit C grubu: EMR, 30 gün boyunca 1 saat/gün C vitamini 250 mg/kg/gün, gavaj ile. Beyaz Kan Hücresi (WBC), Nötrofil, Lenfosit, Monosit, Eozinofil, Bazofil, Kırmızı Kan Hücresi (RBC), Hemoglobin (Hb), Hematokrit (Htc), Ortalama Eritrosit Hacmi (MCV), Kırmızı Hücre Dağılım Genişliği-SD (RDW- SD), Kırmızı Hücre Dağılım Genişliği-CV (RDW-CV), Trombosit (PLT), Ortalama Trombosit Hacmi (MPV), Trombosit Dağılım Genişliği (PDW), Trombosit Krit (PCT) ve Trombosit Büyük Hücre Oranı (P-LCR) sayıları ölçülmüştür. Comet testi ile lenfosit DNA hasarı değerlendirildi, ayrıca malondialdehit (MDA) seviyesi ve katalaz (CAT) aktivitesi değerlendirildi.
Bulgular: Comet analiz skoru ve P-LCR sayıları EMR grubunda Kontrol grubuna göre arttı (p<0,05). C vitamini tedavisi sonrası comet analiz skorunda ve P-LCR sayılarında EMR grubuna göre azalma gözlemledik (p<0,05).
Sonuç: Sonuçlar, bir cep telefonu tarafından üretilen frekansta EMR'nin lenfosit DNA kırılmasına neden olduğunu ve P-LCR seviyesini artırdığını göstermektedir. C vitamini, EMF maruziyetinin neden olduğu lenfosit DNA hasarını ve P-LCR seviyesini azaltıyor gibi görünmektedir.
Structure of genomic DNA in chicken populations revealed by multilocus DNA probe
Authors: Terletskiy Valeriy P. , Tyshchenko Valentina I.
Published: April 2023

Molecular genetic technologies are taking an increasing place in breeding work to improve existing breeds and populations of chickens, as well as in programs to preserve a valuable gene pool. Small local breeds are a source of valuable genes that can be used in breeding. The aim of this work was to obtain new knowledge about the structure of genomic DNA of six chicken populations using multilocus analysis with a labeled molecular probe (GTG)5. Multilocus analysis using labeled DNA probes provides working simultaneously with a large number of genetic loci and calculating population genetic parameters both within populations and between them. The data on use of the multilocus probe (GTG)5 in molecular hybridization reaction in six breeds and populations of chickens were analyzed. The results revealed a large genetic distance between Black-and-White Australorp and the Bald-necked chickens (D = 0.155). Bald-necked chickens are bred in isolation from other breeds to maintain the unique trait of naked necks. According to the criterion of average heterozygosity, the population of Bald-necked chickens surpassed the Yurlov Crowers and Black-and-White Australorps. Obviously, this is due to the intensive breeding work carried out in the last two populations, which reduces genetic diversity. Marker DNA fragments specific for individual breeds were identified. The effectiveness of multilocus analysis as a tool for identifying the features of genome organization in chicken breeds and populations was confirmed.
Effect of L-carnitine administered via subcutaneous injection on hematological parameters of laboratory animals
Authors: Sabirzyanova Lilia I. , Konovalova Gella V. , Tokar Valentina V.
Published: April 2023

To date, there is no registered injectable dosage form of levocarnitine for veterinary use on the territory of the Russian Federation. Based on the above, the purpose of our work was to conduct preclinical studies of L-carnitine of subchronic toxicity for veterinary use in laboratory animals. Experiments to test the toxicity were performed on outbred rats in October 2021 at the vivarium of St. Petersburg State University of Veterinary Medicine. The study involved females weighing 190210 grams, purchased from RAPPOLOVO Laboratory Animal Nursery. To study subchronic toxicity via subcutaneous injection, L-carnitine was administered in 2 dose levels. The doses were determined based on the results of the acute toxicity experiment: 1/5 and 1/10 of the maximum tolerated dose. The first experimental group (n=10) received the drug subcutaneously at a dose of 0.08 mg/kg (1/5 of 2000 mg/kg). The second experimental group (n = 10) received the drug subcutaneously at a dose of 0.04 mg/kg (1/10 of 2000 mg/kg). The control group (n = 10) received sodium chloride 0.09 % subcutaneously at a dose of 1/5 of 2000 mg/kg. The drug was administered subcutaneously daily for 42 days. Killing and blood sampling from the second half of the animals was carried out after assessing the recovery period (10 days after drug cancellation). As a result of studies of subchronic toxicity of subcutaneously administered L-carnitine for veterinary use in laboratory animals, it was found that the dosage of 1/5 of the maximum tolerated, and the dosage of 1/10 of the maximum tolerated, do not cause external signs of toxicosis and death of rats. No significant changes in the hematological parameters of blood of animals from the experimental and control groups were found.
Influence of spent mushroom compost on crop productivity
Authors: Zubkova Tatyana V. , Vinogradov Dmitry V.
Published: April 2023

As development of mushroom industry in Russia is growing, and the amount of spent mushroom composts is increasing, they are actively used as organomineral fertilizers for agricultural crops. Therefore, from the rather large problem of storing waste composts, these fertilizers began to be in great demand in the agricultural industry. Organic fertilizers are characterized by a high percentage of nutrients. They are able to improve physical properties of soil by increasing aggregative stability and reducing soil density. Organic fertilizers improve biological and biochemical properties of soil, and positively affect the development of soil microbial community. In the experiments, the content of nutrients in fresh compost and compost after one year of storage averaged: ash content - 8.0 and 74.1 %; organic matter - 66.3 and 25.9 %; NPK (%) - 0.50, 0.63, 0.44 and 0.45, 0.51, 0.39, respectively, under a favorable soil acidity (pH 8.0-7.3). In studies carried out on dark grey forest soils of the Ryazan region, the maximum productivity of agricultural crops was noted in variants with application of half-ripened compost: the yield of spring wheat was 2.82 t/ha (+ 0.23 t/ha compared to the control); spring barley - 3.21 t/ha (+0.17); spring rapeseed - 1.77 t/ha (+0.24); potato cv. Vympel - 27.91 (+ 4.41); potato cv. Kolobok - 11.21 t/ha (+1.63); pea - 2.10 t/ha (+0.21). The high efficiency of spent mushroom composts as fertilizers for increasing yields of spring barley and wheat, spring rapeseed, potatoes and peas was confirmed.
Morphological criteria for Pipistrellus pygmaeus kidney indicators
Authors: Karpenko Elizaveta N. , Kharlan Alexey L. , Zaitseva Elena V.
Published: April 2023

At present, there is scientific and practical interest in the study of morphological and physiological features, criteria and tolerance of organs involved in protein metabolism in representatives of the order Chiroptera. Macro- and micrometric indicators of kidneys in soprano pipistrelle (Pipistrellus pygmaeus), as a result of adaptive transformations of the body to habitat conditions in the Bryansk region were studied. The study was conducted in the period from 2011 to 2022, 40 captures were carried out with a total of 481 individuals, of which 100 were selected for further study. On histological preparations of kidneys of soprano pipistrelle (Pipistrellus pygmaeus), morphometry of nephrons, podocyte parameters, nuclear-cytoplasmic ratio, areas of nucleolar organizers and their total area were studied. It was established that biological adaptation of the bats (Chiroptera), on the example of soprano pipistrelle (Pipistrellus pygmaeus), is manifested in development of biological properties of the species. The functional and protein-synthetic activity of cells, kidneys (cell volume, nucleus, cytoplasm and nuclear-cytoplasmic ratio), the number and increase in the total area of the argentophilic region of nucleolar organizers were determined by organ topography, gender and influence of anthropogenic negative environmental effects. The data obtained showed gender differences in female bats (Chiroptera) of Pipistrellus pygmaeus species living in an urban environment, having a large number in the colony, against the background of a combined anthropogenic load, under the influence of hydrocarbons, sulfur and nitrogen dioxides and suspended solids. It was found that phenotypic adaptation as an adaptation to flight triggers the main processes of biochemical cycles, the processes of endogenous intoxication and detoxification function in kidneys. In turn, it increases metabolism, which contributes to increase in the number of renal glomeruli and decrease in the cavity of renal glomerular capsule. New data characterizing nuclear-cytoplasmic ratio, number and total area of regions of nucleolar organizers in podocytes of glomeruli in kidneys of soprano pipistrelle (Pipistrellus pygmaeus), which may be a manifestation of genetic adaptation to environmental conditions, were obtained.
Morphometric and chemical parameters of hen carcasses of ‘Smena 9’ cross raised under different conditions
Authors: Kondrashkina Ksenia M. , Nikitchenko Dmitry V. , Nikitchenko Vladimir E.
Published: April 2023

Changes in live weight, morphology of carcasses, their morphometric parameters, chemical composition of muscles during cage rising (group 1) and ground-grazing raising (group 2) were studied in hens (Smena 9 cross) at the age of 1, 35, 42, 49 and 56 days. Generally accepted research methods were used. The hens were raised under the same conditions. The experiments revealed that chickens had a high growth rate at an early age. At 56-day age, live weight of hen from group 1 was 3438 g, which was 2.69 % less than in group 2, and carcass weight was 2.89 % less (P 0.05). In carcasses of broilers from group 2, weight of muscle tissue was 3.14 % more (P 0.05), however, fat and bones were less by 0.22 and 0.09 %, respectively. Compared to 1-day-old chickens, 56-day-old broilers had increased relative weight: muscle tissue in group 1 and group 2 - by 13.04 and 13.27 %, respectively; fat - by 4.02 and 3.80 %, respectively; while relative bone weight decreased by 16.25 and 16.34 % in group 1 and group 2, respectively. Ground-grazing raising of chickens is not inferior in meat productivity to cage rising. At the same time, veterinary and sanitary indicators differ in the quality of meat.
The tree layer structure of forest communities of the Kola Peninsula central part formed when aerotechnogenic emissions reduced
Authors: Evdokimov Alexander S. , Yarmishko Vasily T.
Published: April 2023

This research provides an overview of the main component of forest ecosystems in northern Europe, the tree layer formed by the Scotch pine (Pinus sylvestris L .) species. The studied communities are located in the immediate vicinity of the largest plant in Europe, OAO Severonickel (Monchegorsk, Murmansk region). The main pollutants are polymetallic dust containing elements such as Cu, Ni and Co (which are by-products of processing and smelting non-ferrous ores) and sulfur dioxide - SO2 (which is formed during the primary processing of ores, the so-called “roasting”). The first permanent trial plots (PPPs) in this region were established in the early 1970s. Since the second half of the 1990s, the plant has significantly reduced the amount of aerotechnogenic emissions, as evidenced by the data noted by some researchers at that time. The cumulative nature of the accumulation (and release) of polymetallic dust led to the fact that, starting from the time the ore processing plant reduced its capacity, the concentration of metals contained in the soil and plant organs decreased to a certain level. We present the materials obtained in the course of field research in 2015-2018.
Rewilding in megacities: from concept to implementation
Authors: Fedorchenko Leonid Yu. , Bobkova Arina A. , Nikiforov Andrey I.
Published: April 2023

The expansion of urban agglomerations and the accompanying increase in the severity of environmental problems require special attention to ensure a comfortable urban environment. One of the ways to solve this problem is to create an ecological framework in the megacity, formed by quasi-natural biocenoses, created within the application of the concept of rewilding. This article reviews the main current trends and approaches to the implementation of rewilding; discusses positive and negative environmental effects of the transformation of urban ecosystems within rewilding; presents an analytical review of available techniques and options for rewilding in various megacities around the world.
Research on carbon balance in Japan
Authors: Bancheva Alexandra I.
Published: April 2023

The article presents an overview of scientific publications on the subject of the study «carbon balance in terrestrial ecosystems», made for the territory of Japan and indexed in the Scopus database for the period 2017-2021. Within this theme, the areas with the highest number of articles are highlighted: carbon fluxes in soils, carbon stocks in above ground phytomass (mainly studies of the ecosystems of Hokkaido), features of carbon dioxide sequestration by various plant species typical for Japan, as well as the carbon balance dynamics associated with deforestation, reforestation and natural phenomena such as typhoons. The most active in publishing activity scientific and academic institutions were identified (Forestry and Forest Products Research Institute; National Agriculture and Food Research Organization; Hokkaido University).
The use of a piece sound absorber to reduce the impact of noise on workers in the dairy industry on the example of industrial enterprises of the Republic of Mordovia
Authors: Skvortsov Alexander N.
Published: April 2023

The paper analyzes the working conditions of workers in the dairy industry, which showed that the prevailing harmful production factor is the increased noise level. It has been proven that noise has a negative impact not only on the hearing organs, but also on the whole organism as a whole as a general biological irritant, therefore, reducing noise expansion due to engineering solutions is an urgent task of our time. The article assesses the noise impact on operators of the dairy industry as part of a special assessment of working conditions. The analysis showed that the excess noise level is observed at all workplaces. To protect workers from an increased noise level, a design of a sound-suppressing piece sound absorber is proposed, which is distinguished by high sanitary and hygienic properties. The use of sound-suppressing piece sound absorbers will improve working conditions from a harmful class to an acceptable one.
Features of the relationship between elemental composition and immune reactions in representatives of ethno-demographic groups of the North-East of Russia
Authors: Gorbachev Anatoly L. , Kirichuk Anatoly A. , Pokhilyuk Natalya V.
Published: April 2023

The content of some chemical elements that support immune responses (selenium, zinc, iron, iodine) was analyzed among representatives of the ethno-demographic groups of the North-East of Russia - natives (Chukchi, Koryaks, Evens), mestizos, and newcomers. A potential risk group for the development of hyposelenoses is the Koryak ethnic group. The minimum values of zinc were found among the Chukchi. In representatives of all ethno-demographic groups, the iron content was within the reference values, but its maximum values were noted in the newcomers. The maximum iodine levels are also characteristic of the newcomers. Comparable iodine content was noted in the Evens group. Features of the elemental status (selenium, zinc, iron, iodine) in the inhabitants of the north indicate that among the ethno-demographic groups, it is the aboriginal ethnic groups that are most predisposed to the development of immunodeficiency states.
Bioremediation of polluted soils with pesticides using microorganisms - situation in Colombia
Authors: Zambrano-Gary Cesar C. , Kirichuk Anatoly A.
Published: April 2023

The analysis of the scientific literature on the subject of bioremediation in Latin America countries shows that due to the excessive and uncontrolled use of pesticides in agriculture, there are negative impacts on the environment, mainly on soil and water, as well as on human health. However, through processes such as bioremediation, which utilize the metabolic potential of microorganisms such as bacteria and fungi, it is possible to reduce the impact of pesticides on the environment and human health, which are key factors for achieving sustainable development. Colombia has a severe pesticide pollution problem, as the uncontrolled use of pesticides has affected not only the environment but also human health. Thus, bioremediation is a good alternative to the restoration of a polluted environment and the reduction of its impact on human health.
Influence of the elemental composition of water and soil on the environmental portrait of teenagers in Khabarovsky Kray
Authors: Nesterenko Alena O. , Evseeva Galina P. , Tselikh Ekaterina D.
Published: April 2023

The results of studying the content of Fe, Сu, Mo, Zn, Co, Se, Th and U in drinking water, soil and hair of teenagers of different ethnic groups (Nivkhs, Evens, Russians) living in the Khabarovsk Territory are presented. One of the priority directions of the regional policy of the Khabarovsk region is the preservation of the health of indigenous people. In the conditions of a biogeochemical province, the organism develops adaptive mechanisms that compensate for the imbalance of a number of microelements in the environment which occurred for many generations. However, in the areas of compact residence of the indigenous population, there is an increase in the illnesses from 2010 to 2020 among the Nivkhs (Mykolaiv district) and Evens (Okhotsk district) by 1.8 times and 1.4 times, respectively, which indicates the presence of signs of depletion of the functional reserves of the body of indigenous people. In this regard, the assessment of the ecological state of the environment and the analysis of the content of chemical elements in the hair, reflecting the duration and nature of their entry into the organism, is of particular relevance.
Activities of the Karelian State Pedagogical Institute in 1930s
Authors: Filimonchik Svetlana Nikolaevna
Published: April 2023

This article analyzes the organizational, educational, and scientific activities of the Karelian State Pedagogical Institute during the Stalinist modernization of the 1930s. Sources of formation, number, and composition of new social groups of the Karelian urban population: university lecturers and students were identified. The article shows that the institute activities in Karelia significantly increased the availability of higher education for rural youth and the Finno-Ugric peoples' representatives in the 1930s.
Educational everyday life of students of the Yelabuga Teacher’s Institute in 1939–1941
Authors: Maslova Inga Vladimirovna
Published: April 2023

The article is devoted to the study of the educational everyday life of students of the Yelabuga Teacher's Institute during the formation of the system of higher pedagogical education in the USSR. According to the Decree of the Council of People’s Commissars of the RSFSR in 1939, 48 pedagogical schools were transformed into teachers' institutes. Within a few years, a wide network of such institutions was created in the country. Only in the RSFSR in 1940 there were 130 teacher’s institutes, and by 1945 there were already 187 of them. By the decree of the Government of the USSR in Yelabuga, by the beginning of the 1939–1940 academic year, a teacher’s institute of republican significance was created on the basis of a pedagogical school. The study was carried out on the example of the Yelabuga Teachers’ Institute based on the analysis of archival sources and materials from the periodical press.

The study analyzes the main structural components of the educational everyday life of students of the teacher’s institute: temporal characteristics associated with educational activities; organization of the educational process at the institute; observance of generally accepted norms and rules of behavior of students, methods of spending leisure and recreation, culture of food and life. The housing and material and financial conditions of the life of student youth in the conditions of Soviet reality in the pre-war period were studied.