bluuebunny/crossref_metadata_2025 huggingface dataset:
QUALIDADE DE VIDA EM INGRESSANTES E CONCLUINTES DE DIFERENTES CURSOS UNIVERSITÁRIOS
Authors: Vargas Thaiane Moleta , Vargas Leandro Martinez , Cantorani José Roberto Herrera , Pedroso Bruno
Published: December 2020

O presente trabalho teve por objetivo avaliar a percepção da QV de estudantes universitários, comparando as informações obtidas de ingressantes e concluintes de uma IES de Itararé-SP, visando encontrar as diferenças entre os resultados não satisfatórios de QV. Participaram do estudo acadêmicos de diferentes áreas do conhecimento de uma instituição privada de ensino superior de Itararé – SP. Para a mensuração da qualidade de vida foi utilizado o WHOQOL-Bref, para avaliar o nível de atividade física foi utilizado o Questionário Internacional de Atividade Física (IPAQ) e a satisfação com a imagem corporal foi avaliada por meio de Escala de Silhuetas. Também foram coletadas informações sociodemográficas. A amostra foi composta por 343 acadêmicos, dos quais 175 (51,1%) eram homens e 168 (48,9%) eram mulheres, com média de idade de 22,9 ± 5,6 anos. Foram realizadas análises de diferenças entre grupos comparando cada domínio do WHOQOL-Bref com o sexo, períodos de formação, classes socioeconômicas, níveis de atividade física e satisfação com a imagem corporal. Conclui-se que o sexo, o nível de atividade física e a satisfação com a IC influenciam significativamente na percepção da QV dos estudantes pesquisados. Ao comparar a percepção da QV entre os períodos de formação verificam-se que os estudantes concluintes apresentaram melhores resultados nas facetas relacionadas ao domínio ambiente, quando comparados aos estudantes ingressantes.
Desenvolvimento de cachaça saborizada com pimenta
Authors: Duarte Gustavo Rodrigues , Viana Leticia Fleury , Machado Adriana Rodrigues
Published: December 2020

O objetivo deste trabalho foi produzir cachaça adicionando na etapa de destilação um blend com diferentes concentrações de pimenta Cumari do Pará (Capsicum Chinense Jacqui) e pimenta dedo de moça (Capsicum Baccatum), com o intuito de saborizar e aromatizar a bebida. Conforme descrito por legislação, cachaça é a bebida com graduação alcoólica de 38% vol. (trinta e oito por cento em volume) a 48% vol. (quarenta e oito por cento em volume) a 20ºC (vinte graus Celsius), obtida pela destilação do mosto fermentado do caldo de cana-de-açúcar. Foram desenvolvidas três formulações de cachaça saborizada com diferentes concentrações de pimentas e submetidas as análises físico-químicas afim de comparar os seus resultados com o proposto pela legislação. Os parâmetros analisados foram: teor alcóolico, acidez volátil, extrato seco e pH, além de avaliar a colorimetria das formulações obtidas. Para as três amostras não houve diferença significativa quanto ao teor alcóolico e pH estando esse resultado de acordo com a legislação, para as análises de acidez volátil e extrato seco a amostra três apresentou um valor acima do permitido se tornando imprópria para consumo e todas as amostras apresentaram coloração límpida e neutra. A cachaça obtida apresentou sabor e aroma característico das pimentas utilizadas no processo.
Atividade antioxidante de pequenas frutas produzidas no Estado do Rio Grande do Sul, Brasil
Authors: Lameiro Magna da Gloria Silva , Machado Maria Inês Rodrigues , Machado Adriana Rodrigues , Helbig Elizabete , Zambiazi Rui Carlos
Published: December 2020

A busca por pequenos frutos, por consumidores, tem aumentado nos ultimos tempos devido as grandes pesquisas sobre bioativos, que trazem benefícios associados à manutenção e bem-estar da saúde. Com isso, as agroindústrias também têm focado na expansão do mercado consumidor de polpas de frutas. Assim sendo, as culturas de amora-preta e mirtilo ganham espaço dentre outras espécies, das pequenas frutas consumidas no Brasil, despertam a atenção de consumidores, processadores de frutas, agentes comercializadores e, por consequência, por produtores em escala familiar, médio e de grande porte. O objetivo deste estudo foi avaliar a atividade antioxidante da polpa in natura, da polpa diluída e da polpa liofilizada de amora-preta cv. Tupy e de mirtilo cv. Powderblue. Foram utilizados frutos de amora-preta (Rubus fruticosus) da cultivar cv.Tupy, e mirtilos (Vaccinium ashei Reade) da cv. Powderblue, ambos cultivados na cidade de Morro Redondo-RS. Os frutos previamente congelados (-18°C) foram mantidos à temperatura ambiente até o descongelamento, e em seguida foram triturados em liquidificador e peneirados para obtenção da polpa, que foram diluidas com água mineral nas proporções de 50% e 75% p/v (polpa: água). As frutas também foram armazendas e retiradas do ultrafreezer (-80°C) e imediatamente liofilizadas, após foram armazenadas em embalagens de polietileno sob congelamento (-20±2°C) até o momento das análises. A atividade antioxidante foi determinada seguindo o método descrito por Brand-Willians. Portanto, verificou-se que a polpa -in natura de mirtilo cv. Powderblue apresenta maior capacidade antioxidante que a amora- preta cv. Tupy.
Tratamentos pré-germinativos em sementes e emergência de plântulas de Garcinia acuminata
Authors: Mendes Nouglas Veloso Barbosa , Nascimento Walnice Maria Oliveira do , Lima Denise de Castro , Tavares Rozane Franci de Moraes , Malcher Deyse Jacqueline da Paixão
Published: December 2020

O objetivo do trabalho foi avaliar a eficácia de tratamentos pré-germinativos para germinação de sementes e emergência de plântulas de Garcinia acuminata. O experimento foi realizado no Laboratório de Frutíferas da Embrapa Amazônia Oriental, Belém, Pará. Foi conduzido em ambiente protegido e desprovido de controles de temperatura e de umidade relativa do ar. A determinação do teor de água foi feito pelo método da estufa a 105±3 ºC, utilizando-se quatro amostras de dez sementes antes e depois da aplicação dos tratamentos. Adotou-se o delineamento inteiramente casualizado em fatorial (2 x 5), sendo: tratamentos na semente (com e sem tegumento) e níveis de embebição (sem embebição, embebição em água destilada, embebição em concentrações de 200, 400 e 600 mg.L-1 AG3 por 24 horas), com quatro repetições de 50 sementes em cada. Foi avaliado porcentagem de emergência, índice de velocidade de emergência, tempo médio de emergência, massa seca da parte aérea, massa seca da raiz, comprimento da parte aérea e comprimento da raiz. As médias obtidas no experimento foram comparadas pelo teste de Scott-knott ao nível de 5% de probabilidade. A embebição das sementes com ou sem tegumento, em solução de AG3 na concentração de 600 mg.L-1 durante 24 horas, acelera a germinação das sementes e a emergência das plântulas de G. acuminata. A retirada de tegumento e a embebição em AG3 é requerido para acelerar e uniformizar o processo germinativo de sementes de G. acuminata.
A urgência de monitorar remanescentes florestais em áreas urbanas situadas na restinga
Authors: Cunha Tupi Rodrigues , Borges Roberto Pereira , Seabra Alessandra Aloise de
Published: December 2020

Desde a colonização, o manejo da Mata Atlântica no Brasil, em especial da vegetação de restinga localizada nas zonas costeiras, representa um desafio a ser enfrentado por toda a sociedade costeira. Os dados são alarmantes e ratificam a perda de áreas de florestas nestes cinco séculos de história, concomitante ao aumento da urbanização nas regiões costeiras, comprovando a dificuldade em conciliar ocupação humana e preservação florestal. Este trabalho preenche um hiato legal, recorrente em áreas urbanas ou de expansão urbana localizadas nas regiões costeiras, relacionado à convivência entre os remanescentes florestais e as áreas antropizadas, situados na mesma propriedade em consequência das determinações legais vigentes no país, através de Diretrizes para Aplicação de Faixas de Amortecimento Privativas - FAPs na Restinga, destinadas a empreendimentos com maior impacto ambiental, licenciados através de RAP – Relatório Ambiental Preliminar ou EIA RIMA – Estudo de Impacto Ambiental e Relatório de Impacto Ambiental. Objetivou-se a definição de técnicas interdisciplinares para localizar, dimensionar e monitorar o remanescente florestal preservado na propriedade, além de aferir impactos que ocorrem durante e após a supressão de vegetação, na implantação e operação da atividade licenciada. Este trabalho concluiu pela viabilidade das FAPs, após análise e discussão dos resultados, das legislações, normas, notas e pareceres técnicos relacionados às Áreas Verdes Remanescentes na Propriedade, de Preservação Permanente e as Unidades de Conservação. Este último assunto foca a gestão e dimensão das Zonas de Amortecimento, técnicas de Biomonitoramento e conceitos de Planejamento Estratégico, Ecologia da Paisagem, Dupla Territorialidade, Sistemas Sócio Ecológicos, Manejo Adaptativo e Serviços Ecossistêmicos.
Desafios dos enfermeiros na preparação de casais para o parto
Authors: Sousa Ana Jessyca Campos , Silva Maria Adelane Monteiro da , Nour Guilherme Frederico Abdul , Moreira Andréa Carvalho Araújo , Freitas Cibelly Aliny Siqueira Lima , Sousa Conceição de Maria Farias , Silva Ana Celia Oliveira
Published: December 2020

Objetiva-se conhecer as necessidades de enfermeiros na preparação do casal para o parto. Trata-se de um estudo exploratório com abordagem qualitativa. Para análise das informações foi utilizada a técnica de Análise Temática. O estudo tem a aprovação do Comitê de Ética em Pesquisa (CEP) da Universidade Estadual Vale do Acaraú (UVA), com parecer número 2.442.627. A partir da análise temática, emergiram três categorias: Participação paterna na gestação; Desconhecimento dos profissionais na preparação do casal para o parto; Metodologias/Recursos utilizadas no preparo do casal para o parto. A partir do estudo foi possível identificar os desafios que os enfermeiros enfrentam para realizar a preparação para o parto. A partir do estudo foi possível identificar os desafios que os enfermeiros enfrentam na preparação do casal para o parto. A dificuldade de envolver o pai nessas abordagens impede a atuação do enfermeiro na APS dentro desse enfoque. Ademais, a insegurança e o distanciamento dos profissionais com a temática tem forte contribuição negativa. Sugerem-se mais estudos que tratem da temática e que objetivem a promoção do envolvimento paterno durante o parto e nascimento, visando a qualificação do cenário parturitivo brasileiro.
Persistence of intrahepatic hepatitis B virus DNA integration in patients developing hepatocellular carcinoma after hepatitis B surface antigen seroclearance
Authors: Jang Jeong Won , Kim Jin Seoub , Kim Hye Seon , Tak Kwon Yong , Nam Heechul , Sung Pil Soo , Bae Si Hyun , Choi Jong Young , Yoon Seung Kew , Roberts Lewis R.
Published: December 2020

Background/Aims: The role of hepatitis B virus (HBV) integration into the host genome in hepatocarcinogenesis following hepatitis B surface antigen (HBsAg) seroclearance remains unknown. Our study aimed to investigate and characterize HBV integration events in chronic hepatitis B (CHB) patients who developed hepatocellular carcinoma (HCC) after HBsAg seroclearance.
Methods: Using probe-based HBV capturing followed by next-generation sequencing technology, HBV integration was examined in 10 samples (seven tumors and three non-tumor tissues) from seven chronic carriers who developed HCC after HBsAg loss. Genomic locations and patterns of HBV integration were investigated.
Results: HBV integration was observed in six patients (85.7%) and eight (80.0%) of 10 tested samples. HBV integration breakpoints were detected in all of the non-tumor (3/3, 100%) and five of the seven (71.4%) tumor samples, with an average number of breakpoints of 4.00 and 2.43, respectively. Despite the lower total number of tumoral integration breakpoints, HBV integration sites in the tumors were more enriched within the genic area. In contrast, non-tumor tissues more often showed intergenic integration. Regarding functions of the affected genes, tumoral genes with HBV integration were mostly associated with carcinogenesis. At enrollment, patients who did not remain under regular HCC surveillance after HBsAg seroclearance had a large HCC, while those on regular surveillance had a small HCC.
Conclusions: The biological functions of HBV integration are almost comparable between HBsAg-positive and HBsAgserocleared HCCs, with continuing pro-oncogenic effects of HBV integration. Thus, ongoing HCC surveillance and clinical management should continue even after HBsAg seroclearance in patients with CHB.
Evaluation and management of extrahepatic manifestations of nonalcoholic fatty liver disease
Authors: Wijarnpreecha Karn , Aby Elizabeth S. , Ahmed Aijaz , Kim Donghee
Published: December 2020

Nonalcoholic fatty liver disease (NAFLD) is a multisystemic disease and a rapidly growing cause of chronic liver disease in children and adults worldwide. Diagnosis and management of extrahepatic manifestations of NAFLD, including cardiovascular disease (CVD), type 2 diabetes mellitus, metabolic syndrome, chronic kidney disease, obstructive sleep apnea, polycystic ovarian syndrome, hypothyroidism, psoriasis, and extrahepatic malignancy are crucial for the treatment of patients with NAFLD. The leading cause of death in NAFLD is primarily from CVD, followed by liver-related mortality, extrahepatic cancer, liver cancer, and diabetes-related mortality. Therefore, clinicians need to identify high-risk patients earlier in the disease course and be aware of the extrahepatic manifestations of NAFLD to improve liver disease outcomes. In this review, we focus on the monitoring and management of the extrahepatic manifestations of NAFLD.
Suchey-Brooks yaş tahmini yönteminin Türk popülasyonunda 3 boyutlu pubis simfisiz görüntüleri kullanılarak değerlendirilmesi
Authors: GÜLHAN Öznur
Published: December 2020

Yaş tahmini, özellikle adlî antropologlar için biyolojik profil oluşturma sürecinde oldukça kritik ve zaman zaman tanımlanması zor bir süreçtir. Yetişkin iskelet kalıntılarındaki çeşitli morfolojik özellikler gözlemlenerek yaş tahmini için belirli standartlar oluşturulmasında kullanılabilmektedir. Bu iskelet elementlerinin en başında pubis simfisiz gelmektedir. Günümüzde pubis simfisizden yaş tahmini için en yaygın olarak kullanılan yöntem, 6 fazlı bir sistem olan Suchey-Brooks yöntemidir. Bu yöntem çok sayıda osteolojik koleksiyon veya sanal örnek üzerinde geniş çapta test edilmiş ve bu yaş tahmini yönteminin genellikle popülasyon varyasyonlarından etkilendiği belirtilmiştir. Bu sebeple bu çalışmada BT görüntülerinden elde edilen modern Türk popülasyonuna ait pubis simfisiz modelleri üzerinde Suchey-Brooks yönteminin güvenilirliği test edilmiştir. Suchey-Brooks yöntemi kullanılarak yaş tahmini yapmak için modern Türk popülasyonuna ait 120 bireyin (60 Kadın, 60 Erkek) bilgisayarlı tomografi görüntülerinden elde edilen üç boyutlu rekonstrüksiyonları araştırmada kullanılmıştır. Çalışmanın sonuçları, Suchey-Brooks yöntemi için hem yanlılık hem de yanlışlık düzeylerinin yaşla birlikte arttığını ve yaş ilerledikçe gerçek yaşın daha küçük tahmin edilme eğiliminde olduğunu göstermektedir. Sonuç olarak, yetişkin bireylerin yaşını tahmin etmeye yönelik kullanılan yöntemlerin, yöntemin geliştirildiği örneklem ile uygulandığı çalışma arasındaki yer ve zaman farklılıklarını en aza indirmek için farklı popülasyonlarda test edilmesi gerekmektedir.
Online Testing in Teaching Mathematics: Problems and Opportunities of Distance Learning
Authors: Mukhamedova G.
Published: December 2020

Teaching mathematics in distance education has uncovered many problems and possibilities. The objective of this paper was to expose the obstacles and potentials of distance education based on the practices of Universitas Terbuka in offering mathematics courses. Modern technology of on-line testing is becoming more widely used in teaching mathematics. The advantages and disadvantages of this method of teaching and knowledge control are discussed. The analysis of the vulnerabilities of the testing procedure is given.
Pedagogical Conditions for the Organization of Distance Online Trainings in Kyrgyzstan in a Pandemic Period
Authors: Omurkanova Ch.
Published: December 2020

The scientific article considers various views on the pedagogical conditions of organizing distance learning in the universities of Kyrgyzstan, in a pandemic. The pedagogical conditions I distance learning (DL) presented problems requiring a solution to the pedagogical process. A pedagogical condition, in the learning process, emphasize a set of measures aimed at solving urgent problems in the organization of distance learning, purposefully implemented in the learning process and meeting the specifics of forms of distance learning.
The Role of Local Industry and Producers’ and Disabled People’s Cooperatives in Increasing the Goods Turnover in Bashkiria in 1944 To 1945
Authors: Antoshkin A.
Published: December 2020

The article is dedicated to the work of local industries, and producers’ and disabled people’s cooperatives manufacturing consumer goods in Bashkiria in 1944 to 1945. The archive materials first introduced into the scientific scrutiny in this article show important contribution of producers’ and disabled people’s cooperation to the growth of the goods turnover in Bashkiria. During the Great Patriotic War, the centralized funds were reduced significantly. The turnover of the state-owned trading organizations and consumer cooperation dropped. Considerable resources were withdrawn to meet the urgent needs of the Army. These economic hardships necessitated the producers’ and disabled people’s cooperative societies to step in and by using local resources and industrial waste to make up for the shortage of consumer goods in the trading system of Bashkiria. Those goods were needed for satisfying the demand for consumer goods by local and evacuated people. The study showed different infringements of contractual arrangements between cooperatives and trading organizations. It disclosed the causes of the failure of production plans. There were cases of embezzling scarce goods, cases of self-supplying. Often the distribution of goods was performed outside the legal trading network. Inspections regularly found embezzlement and theft of significant amounts of produce. The conclusion is that the aforementioned set of infringements was one of the causes of the failure of the turnover plan in the state trading system in Bashkiria.
Durability of Clay Architecture Monuments of Khorezm Oasis
Authors: Khuzhaniezov Sh. , Siddikov M.
Published: December 2020

The results of the experimental study of MG, the possibility of using modified clay with a new composition was established, a method of heat treatment is recommended for the restoration of architectural clay-raw monuments and the construction of new low-rise residential buildings in seismically active regions.
Specific Features of Country Population Settlements in Surkhandarya Region
Authors: Sattarov A.
Published: December 2020

This article highlights information about the population, the location of settlements, the housing of the population, the structure of dwellings, as well as the economic, social, and geographical changes that influenced the development of the region, it should be noted that the study of population growth, the location of settlements has great economic and social importance.
Brief Overview of Semantic Description of Spatial Elements in Azerbaijani Fairy Tales
Authors: Khudaverdiyeva T.
Published: December 2020

In fairy tales, space plays an important role and acts as a structural element of fairy tales, performing a certain function within the fairy tale. Therefore, it is impossible to imagine fairy tales without the elements of space. As it is mentioned in the article, the world of fairy tales consists of numerous transformations and changes of spatial elements. The article gives a brief overview of semantic description of the spatial elements in the Azerbaijan fairy tales on the bases of five volume book of the Azerbaijan fairy tales. The article also identifies the functions of the words describing spatial elements. It investigates the transformations of spatial elements in the fairy tales. It notes that the spatial elements make up the archaic world model and participate in the formation of fairy tales. The article searches the semantic structure of the fairy tales with exact examples from them.
Geri Çekilmiştir: Cevher-Araz Teorisinin İnsan Fiilleri Konusundaki Yaklaşımlara Etkisi
Authors: Altındas Mücteba
Published: December 2020

Bu makale, yazarın eş zamanlı yayınlanan başka makaleleriyle (10.18403/emakalat.790794 ve 10.18505/cuid.686675) kabul edilemez derecede örtüşme içerdiğinden dolayı editörlerin kararıyla geri çekilmiştir. This article has been retracted at the request of the editors as it contains unacceptable overlap with the other studies of the author (10.18403/emakalat.790794 ve 10.18505/cuid.686675) published simultaneously.
Якість кримінального процесуального законодавства України, яке регулює підстави та порядок застосування застави
Authors: Крайник Г.С. , Дунаєва Т. Є.
Published: December 2020

У статті досліджено актуальні питання щодо застави як запобіжного заходу. Запропоновано законодавчі зміни до ст. 182 Кримінального процесуального кодексу України, які належним чином урегулюють питання застосування застави в Україні та усунуть існуючі недоліки. Обґрунтовано необхідність змін до ст. 182 Кримінального процесуального кодексу України та запровадження застави в негрошовій формі. Чинну редакцію ст. 299 Кримінального процесуального кодексу України запропоновано вдосконалити шляхом надання можливості застосування застави при здійсненні кримінальних проступків. Також убачається доцільним доповнити ч. 1 ст. 335 та ч. 9 ст. 335 Кримінального процесуального кодексу України положенням про рішення в резолютивній частині обвинувального вироку питання про повернення застави заставодавцю. Запровадження вказаних пропозицій буде сприяти удосконаленню якості кримінального процесуального законодавства України щодо застави як запобіжного заходу.
Деякі аспекти забезпечення безпеки осіб в умовах протидії досудовому розслідуванню
Authors: Плетенець В.М.
Published: December 2020

Стаття присвячена розгляду окремих аспектів забезпечення безпеки осіб в умовах протидії досудовому розслідуванню. У роботі наголошується, що однією з причин сформованої криміногенної обстановки є тиск на учасників кримінального провадження. Звертається увага, що, наприклад, так звані добросовісні учасники (свідки, потерпілі, співучасники), відчуваючи загрозу безпеці власній або близьким, можуть відмовлятися від раніше даних свідчень, змінювати їх, уникати явки до правоохоронних органів, залишати місце постійного мешкання тощо. Наголошується, що між кількістю отримуваної в ході розслідування інформації та відчуттям захищеності відповідним учасником провадження може бути простежена пряма залежність.
Нова концепція конституційних основ правового статусу суддів в Україні
Authors: Іваницький С. О.
Published: December 2020

Рецензія підготовлена на монографію «Конституційні основи правового статусу суддів в Україні», автором якої є кандидат юридичних наук, доцент, доцент кафедри теорії та історії держави і права Східноєвропейського національного університету імені Лесі Українки (м. Луцьк) Володимир Миколайович Кравчук. Це дослідження актуальне не лише для конституційно-правової та судоустрійної науки, а й для правозастосовної діяльності. Нині вагомий інтерес до конституційних основ правового статусу суддів, його сутності, змісту та структурних елементів викликаний одразу багатьма чинниками. Дане питання лишається актуальним як у рамах новітнього конституційного процесу, першочерговим завданням якого є оновлення Конституції України, так і в межах удосконалення законодавства про судоустрій та статус суддів.
Відповідальність держави за знищення цивільних повітряних суден: особливості міжнародно-правового та національного регулювання
Authors: Камінська Н.В. , Акімов М. О.
Published: December 2020

У статті здійснено аналіз існуючих міжнародно-правових та деяких національних джерел як підстав настання відповідальності держави за знищення цивільних повітряних суден поряд з іншими неправомірними діяннями у сфері міжнародної цивільної авіації. Це зумовило вивчення стану міжнародно-правового та національного правового регулювання інституту відповідальності держави. Розкрито особливості притягнення до відповідальності держав як основних суб’єктів повітряного права, на відміну від фізичних та юридичних осіб, міжнародних організацій, інших суб’єктів. Хоча знищення та пошкодження цивільного повітряного судна в польоті суперечить принципу безпеки цивільної авіації, закріпленому Чиказькою конвенцією та вимогам утримуватися від застосування зброї до цивільного повітряного судна в польоті, встановлених Протоколом щодо змін Конвенції про міжнародну цивільну авіацію 1984 р. (Монреальський протокол), такі акти набули загрозливого поширення. У цілому міжнародно-правова відповідальність держави за знищення цивільного повітряного судна та, зокрема, порядок примусового виконання нею відповідних зобов’язань у частині відшкодування збитків залишаються недостатньо врегульованими, ґрунтуються здебільшого на звичаєвих положеннях, а відтак, потребують подальшої міжнародної і національної правотворчої діяльності.
THE VERSATILITY OF CREATIVITY V. G. ZABOLOTNY (TO THE 120TH ANNIVERSARY OF THE BIRTH)
Authors: Kutsevych Vadym
Published: December 2020

The architecture of Ukraine of the 20s — the beginning of the 30s of the XXth century was characterized by the search for the national originality of forms based on the understanding of the merits of Ukrainian baroque and folk architecture, a further workshop of the interpretation of the classicism techniques and the receipt of the marked revolutionary romance of architecture.In the 1930s, the stylistic orientation of the architecture of the former USSR and its component part of Ukraine was replaced by directive decrees and the Decree of the Central Committee of the CPSU (b) “On the restructuring of literary and artistic organizations” (1932), created unions of writers, composers and architects. The resulting policy orientation on classical patterns as the basis of the creative method of socialist realism has become a phenomenon inherent in totalitarian regimes.The article discusses the many facets of the creative activity of V.G. Zabolotny, as an architect, scientist and educator, public figure, founder of the Ukrainian school of architecture, founder and president of the Academy of Architecture of the former USSR. The main stages of the work of the architect in the context of the history of the formation and development of Ukrainian architecture of the 30–60-ies of XX century are analyzed.One of the significant creative achievements of V. G. Zabolotny was the fruitful activity in the Academy Architecture of the USSR, which he created, it was discontinued in 1963. In 1992, it was reborn as a public organization — the Ukrainian Academy of Architecture (UAA), called to life by the new socio-economic conditions of the country's development. The UAA revival, continuing the tradition the Academy of Architecture, created byV. G. Zabolotny, makes a significant contribution to the development of Ukrainian architecture as one of the components of Ukrainian national culture.The materials on the multifaceted activity of V.G. Zabolotny presented in the article will contribute to the development of scientific researches on the history and theory architecture of Ukraine in the last century.
Universidade e cidade: uma reconciliação necessária
Authors: Ultramari Clovis , Levy Wilson
Published: December 2020

Este artigo, de caráter predominantemente ensaístico, discute o compromisso social da universidade em territórios específicos, destacando cidades ou regiões em que se inserem. Sua argumentação é feita em dois caminhos analíticos: em nível de fluxos, do conhecimento gerado e possível apropriação por políticas públicas da gestão urbana e regional, e de fixos, pelo entendimento do impacto de suas estruturas físicas na malha de uma cidade. O primeiro caminho serve-se de um debate qualitativo e referencial; o segundo, de um breve estudo bibliométrico sobre o acatamento, pela gestão urbana, daquilo produzido na universidade. Conclui-se por avanços positivos na consideração e compreensão acadêmica e científica do local e do regional que contém nossas universidades e uma fragilidade no caso da consideração e compreensão da universidade pela cidade. Apesar de mudanças serem visíveis, o artigo detecta problemas estruturais que fazem da reconciliação entre universidade e cidade algo ainda mais difícil.
Desafios e aprendizados do Mestrado Profissional em Rede Nacional para Ensino das Ciências Ambientais
Authors: Malheiros Tadeu Fabrício , Kashiwagi Helena Midori , Ortêncio Filho Henrique , Silva Jair Gonçalves da , Martinelli Filho José Eduardo , Cavalcante Katia Viana , Santana Otacílio Antunes
Published: December 2020

A priorização institucional da CAPES para maior diálogo e alcance de professores da educação básica resultou na indução de 11 programas de mestrado em rede nacional, com áreas de concentração e temáticas vinculadas diretamente à melhoria da Educação Básica, com centenas de instituições envolvidas e localizadas nas cinco regiões do Brasil. Neste contexto, este artigo tem como objetivo destacar aspectos-chave da experiência da REDE PROFCIAMB, explorando de-safios e aprendizados na consolidação do programa, enquanto um exemplo positivo de resposta da pós-graduação brasileira frente aos desafios de alinhamento ao desenvolvimento sustentável. O artigo aborda a construção interdisciplinar de uma cultura do mestrado profissional; a estruturação e integração da REDE PROFCIAMB; a interface com a extensão enquanto processo de aprendizagem e impacto social; os produtos educacionais resultantes e sua usabilidade; e finalmente os esforços da REDE para alcançar regiões de contextos críticos quanto à vulnerabilidade socioambiental.
O Programa São Paulo Faz Escola: uma análise da reforma curricular paulista a partir dos estudos de política educacional
Authors: Ortega Daiani Vieira , Militão Silvio César Nunes
Published: December 2020

Neste artigo propomos uma análise da formulação e implemen-tação da reforma curricular no Estado de São Paulo, a partir do Programa São Paulo Faz Escola, com base nos modelos analíticos de políticas públicas de pesquisadores anglo-saxões, cujas contribuições foram discutidas por Viana (1996) e Rua (2013), e no ciclo de políticas de Stephan Ball e Richard Bowe (1992). Constatamos que a questão da qualidade da educação entrou na agenda governamental no contexto de ascensão da ideologia neoliberal no país e a reforma curricular surgiu como alternativa para melhoria dos índices educacionais, sendo imple-mentada de forma programada sem participação dos professores no processo decisório, em consonância com outras políticas em âmbito nacional e estadual.
A New Click-Through Rates Prediction Model Based on Deep&Cross Network
Authors: Huang Guojing , Chen Qingliang , Deng Congjian
Published: December 2020

With the development of E-commerce, online advertising began to thrive and has gradually developed into a new mode of business, of which Click-Through Rates (CTR) prediction is the essential driving technology. Given a user, commodities and scenarios, the CTR model can predict the user’s click probability of an online advertisement. Recently, great progress has been made with the introduction of Deep Neural Networks (DNN) into CTR. In order to further advance the DNN-based CTR prediction models, this paper introduces a new model of FO-FTRL-DCN, based on the prestigious model of Deep&Cross Network (DCN) augmented with the latest optimization technique of Follow The Regularized Leader (FTRL) for DNN. The extensive comparative experiments on the iPinYou datasets show that the proposed model has outperformed other state-of-the-art baselines, with better generalization across different datasets in the benchmark.
Dietary Application of Tannins as a Potential Mitigation Strategy for Current Challenges in Poultry Production: A Review
Authors: Choi Janghan , Kim Woo Kyun
Published: December 2020

The poultry industry has an important role in producing sources of protein for the world, and the size of global poultry production continues to increase annually. However, the poultry industry is confronting diverse challenges including bacterial infection (salmonellosis), coccidiosis, oxidative stress, including that caused by heat stress, welfare issues such as food pad dermatitis (FPD) and nitrogen and greenhouse gasses emissions that cumulatively cause food safety issues, reduce the efficacy of poultry production, impair animal welfare, and induce environmental issues. Furthermore, restrictions on the use of AGP have exacerbated several of these negative effects. Tannins, polyphenolic compounds that possess a protein precipitation capacity, have been considered as antinutritional factors in the past because high dosages of tannins can decrease feed intake and negatively affect nutrient digestibility and absorption. However, tannins have been shown to have antimicrobial, antioxidant and anti-inflammatory properties, and as such, have gained interest as promising bioactive compounds to help alleviate the challenges of AGP removal in the poultry industry. In addition, the beneficial effects of tannins can be enhanced by several strategies including heat processing, combining tannins with other bioactive compounds, and encapsulation. As a result, supplementation of tannins alone or in conjunction with the above strategies could be an effective approach to decrease the need of AGP and otherwise improve poultry production efficiency.
Efficient Learning of Healthcare Data from IoT Devices by Edge Convolution Neural Networks
Authors: He Yan , Fu Bin , Yu Jian , Li Renfa , Jiang Rucheng
Published: December 2020

Wireless and mobile health applications promote the development of smart healthcare. Effective diagnosis and feedbacks of remote health data pose significant challenges due to streaming data, high noise, network latency and user privacy. Therefore, we explore efficient edge and cloud design to maintain electrocardiogram classification performance while reducing the communication cost. These contributions include: (1) We introduce a hybrid smart medical architecture named edge convolutional neural networks (EdgeCNN) that balances the capability of edge and cloud computing to address the issue for agile learning of healthcare data from IoT devices. (2) We present an effective deep learning model for electrocardiogram (ECG) inference, which can be deployed to run on edge smart devices for low-latency diagnosis. (3) We design a data enhancement method for ECG based on deep convolutional generative adversarial network to expand ECG data volume. (4) We carried out experiments on two representative datasets to evaluate the effectiveness of the deep learning model of ECG classification based on EdgeCNN. EdgeCNN shows superior to traditional cloud medical systems in terms of network Input/Output (I/O) pressure, architecture cost and system high availability. The deep learning model not only ensures high diagnostic accuracy, but also has advantages in aspect of inference time, storage, running memory and power consumption.
Nucleus Accumbens-Associated Protein 1 Binds DNA Directly through the BEN Domain in a Sequence-Specific Manner
Authors: Nakayama Naomi , Sakashita Gyosuke , Nagata Takashi , Kobayashi Naohiro , Yoshida Hisashi , Park Sam-Yong , Nariai Yuko , Kato Hiroaki , Obayashi Eiji , Nakayama Kentaro , Kyo Satoru , Urano Takeshi
Published: December 2020

Nucleus accumbens-associated protein 1 (NAC1) is a nuclear protein that harbors an amino-terminal BTB domain and a carboxyl-terminal BEN domain. NAC1 appears to play significant and diverse functions in cancer and stem cell biology. Here we demonstrated that the BEN domain of NAC1 is a sequence-specific DNA-binding domain. We selected the palindromic 6 bp motif ACATGT as a target sequence by using a PCR-assisted random oligonucleotide selection approach. The interaction between NAC1 and target DNA was characterized by gel shift assays, pull-down assays, isothermal titration calorimetry (ITC), chromatin-immunoprecipitation assays, and NMR chemical shifts perturbation (CSP). The solution NMR structure revealed that the BEN domain of human NAC-1 is composed of five conserved α helices and two short β sheets, with an additional hitherto unknown N-terminal α helix. In particular, ITC clarified that there are two sequential events in the titration of the BEN domain of NAC1 into the target DNA. The ITC results were further supported by CSP data and structure analyses. Furthermore, live cell photobleaching analyses revealed that the BEN domain of NAC1 alone was unable to interact with chromatin/other proteins in cells.
Combined Cell Therapy in the Treatment of Neurological Disorders
Authors: Namestnikova Daria D. , Cherkashova Elvira A. , Sukhinich Kirill K. , Gubskiy Ilya L. , Leonov Georgy E. , Gubsky Leonid V. , Majouga Alexander G. , Yarygin Konstantin N.
Published: December 2020

Cell therapy of neurological diseases is gaining momentum. Various types of stem/progenitor cells and their derivatives have shown positive therapeutic results in animal models of neurological disorders and in clinical trials. Each tested cell type proved to have its advantages and flaws and unique cellular and molecular mechanism of action, prompting the idea to test combined transplantation of two or more types of cells (combined cell therapy). This review summarizes the results of combined cell therapy of neurological pathologies reported up to this point. The number of papers describing experimental studies or clinical trials addressing this subject is still limited. However, its successful application to the treatment of neurological pathologies including stroke, spinal cord injury, neurodegenerative diseases, Duchenne muscular dystrophy, and retinal degeneration has been reported in both experimental and clinical studies. The advantages of combined cell therapy can be realized by simple summation of beneficial effects of different cells. Alternatively, one kind of cells can support the survival and functioning of the other by enhancing the formation of optimum environment or immunomodulation. No significant adverse events were reported. Combined cell therapy is a promising approach for the treatment of neurological disorders, but further research needs to be conducted.
A Child Who Suddenly Freezes While Trying to Cross Crosswalks—Unique Clinical Manifestation of Paroxysmal Kinesigenic Dyskinesia: A Case Report
Authors: Kim Sae Yoon , Ahn JiYoung , Kwak Soyoung , Chang Min Cheol
Published: December 2020

(1) Background: We report the case of a patient with a unique clinical presentation of inability to cross crosswalks due to paroxysmal kinesigenic dyskinesia (PKD). (2) Case presentation: A 14-year-old boy presented with the inability to move his right leg at gait initiation from the standing position. This episode lasted for approximately 20–30 s and manifested 1–3 times a day. The difficulty in gait initiation usually occurred when the patient tried to cross crosswalks when the traffic light turned from red to blue. His right arm stiffened occasionally while trying to write with a pencil and eat food with a spoon or chopsticks. Other neurological manifestations and pain were absent during these episodes. No neurological symptoms were observed between the attacks. Brain magnetic resonance imaging did not reveal any abnormalities. A next-generation sequencing study revealed a pathological variant in the proline-rich transmembrane protein 2 (PRRT2) gene. The patient was diagnosed with PKD. His symptoms disappeared completely after treatment with carbamazepine (100 mg/day). (3) Conclusions: The symptoms of PKD can be successfully controlled using antiepileptic medications. Therefore, clinicians should be aware of the clinical manifestations of PKD to provide appropriate treatment.
Early Intervention with Parents of Children with Autism Spectrum Disorders: A Review of Programs
Authors: Rojas-Torres Liliana Paulina , Alonso-Esteban Yurena , Alcantud-Marín Francisco
Published: December 2020

The aim of this article was to analyze the evidence regarding the effectiveness of intervention programs for children with autism based on the participation of their parents. To obtain the data, a systematic search was carried out in four databases (PsycARTICLES (ProQuest), ERIC (ProQuest), PubMed (ProQuest), and Scopus). The retrieved documents were refined under the inclusion/exclusion criteria, and a total of 51 empirical studies were selected. These studies were first classified according to the function of the intervention objective and, later, by the methodology applied (19 studies were based on comprehensive interventions, 11 focused on the nuclear symptoms of autism spectrum disorder (ASD), 12 focused on the promotion of positive parenting, and nine interactions focused on child play). Once all of the documents had been analyzed, the evidence indicated scientific efficacy in most studies, mainly in those based on child development and the application of behavioral analysis principles. Moreover, the positive influence of parent participation in such programs was demonstrated.
Local Institutions and Climate Change Adaptation: Appraising Dysfunctional and Functional Roles of Local Institutions from the Bilate Basin Agropastoral Livelihood Zone of Sidama, Southern Ethiopia
Authors: Bekele Firew , Tolossa Degefa , Woldeamanuel Teshale
Published: December 2020

This study aimed to appraise the role of local institutions in adaptation to changing climate at the local level in the Bilate Basin Agropastoral Livelihood Zone of Ethiopia. Thirty-one years of climate data were analyzed by employing the Mann–Kendall trend and Sen’s slope test techniques. The survey was conducted on 400 households that were systematically randomized from 7066 households, while community-level data were collected through the participatory rural appraisal (PRA) technique. The entire analysis was framed by a tetragonal model. The results of the analysis indicated that temperature exhibited a significantly increasing trend, while rainfall, which is statistically related to temperature, showed a decreasing trend, resulting in lingering droughts and human and animal diseases. Major livestock declined by 69%. As a response, while Sidama indigenous institutions were well-functioning and nurtured through local knowledge, and the governmental and civic ones were entrenched with various limitations. Contextual fitness and compatibility, interplay, inclusiveness, and sustainability of their operations in temporal and spatial scales were some of their limitations. Therefore, federal and local governments should focus on monitoring, evaluating, and learning aspects of their grand strategies, review general education, farmers’ credit, and civic institutions’ governance policies and strengthen the synergy of civic, government, and indigenous institutions.
Prospects for the Improvement of Bioethanol and Biohydrogen Production from Mixed Starch-Based Agricultural Wastes
Authors: Aruwajoye Gabriel S. , Kassim Alaika , Saha Akshay K. , Gueguim Kana Evariste B.
Published: December 2020

The need for fossil fuel alternatives keeps increasing. Bioethanol and biohydrogen have emerged as significant renewable options. However, these bioprocess routes have presented various challenges, which constantly impede commercialization. Most of these bottlenecks are hinged on feedstock logistics, low biofuel yield and enormous process costs. Meanwhile, a large output of renewable energy can be generated from mixed starch-based agricultural wastes due to their intrinsic bioenergy characteristics. This study, therefore, focuses on the production of bioethanol and biohydrogen from mixed starch-based agricultural wastes. The content further highlights the current challenges of their individual processes and elucidates the prospects for improvement, through an integrated biofuel approach. The use of mixed starch-based agricultural wastes as substrates for integrated bioethanol and biohydrogen production was proposed. Furthermore, the use of mixture-based experimental design for the determination of optimal values of critical factors influencing biofuel production emerges as a viable prospect for profitable bioethanol production from the starch-based biomass. Additionally, biohydrogen production from effluents of the mixed starch-based waste bioethanol looked promising. Thus, the study proposed valuable insights towards achieving a cost-effective biofuel technology.
Analysis of Total Phenols, Sugars, and Mineral Elements in Colored Tubers of Solanum tuberosum L.
Authors: Saar-Reismaa Piret , Kotkas Katrin , Rosenberg Viive , Kulp Maria , Kuhtinskaja Maria , Vaher Merike
Published: December 2020

The use of colored tubers of Solanum tuberosum L. is growing worldwide due to their health benefits and attractive color. The positive health effects of purple-fleshed tubers are a result of anthocyanins and various phenolic compounds. The aim of this study was to evaluate and compare variety Blue Congo and its cross-breeds of Desiree and Granola to yellow-fleshed tubers. The concentration of total phenols, anthocyanins, sugars, and mineral elements were evaluated in all tubers. The results showed differences between all tested materials, with largest differences in sugar content. Moreover, the results confirmed the preservation of health improving compounds of Blue Congo when cross-bred with yellow-fleshed tubers. The total phenolic content and anthocyanin concentrations of all analyzed tubers were above the comparison yellow ones.
Polyphenolic Characterization of Nebbiolo Red Wines and Their Interaction with Salivary Proteins
Authors: Azevedo Joana , Brandão Elsa , Soares Susana , Oliveira Joana , Lopes Paulo , Mateus Nuno , de Freitas Victor
Published: December 2020

The present study correlates the polyphenolic composition of two different Nebbiolo red wines from the 2015 vintage (M and P), with the salivary proteins’ precipitation process. The work centered on the polyphenolic characterization of Nebbiolo wines and their interaction with different families of salivary proteins. Overall, both wines were found to be very reactive with human saliva which was supposed to contribute to their astringent character. The comparison of both wines showed that the M wine presented higher values of total phenolics, total proanthocyanidins, and tannin specific activity. Moreover, this wine showed a higher interaction with salivary proteins. Altogether, the chemical characterization and reactivity toward human saliva could contribute to the wine astringency.
Formulations of Rancid and Winey-Vinegary Artificial Olfactory Reference Materials (AORMs) for Virgin Olive Oil Sensory Evaluation
Authors: Aparicio-Ruiz Ramón , Barbieri Sara , Gallina Toschi Tullia , García-González Diego L.
Published: December 2020

Sensory assessment of virgin olive oil (“panel test”) is the only sensory method included in international regulations of edible oils and its application is compulsory. Even if its application has been a success in quality control, improving the quality of virgin olive oils over the last 30 years, at present, there is no reference material (RM), in the strict sense of the term, to be used as a validated standard for sensory defects of virgin olive oil with which tasters can be trained. Usually, real samples of virgin olive oils assessed by many panels for the International Olive Council (IOC) ring tests are used as materials of reference in panel training and control. The latter are highly representative of the main perceived defects, but availability is limited, samples are not homogeneous year after year, and other secondary defects can be present. Thus, in order to provide solutions, this work describes an analytical procedure for implementing olfactory formulations that emulate rancid and winey-vinegary defects found in virgin olive oils with the aim of providing reproducible RMs that can be prepared on demand. A strategy for designing RMs for aroma is presented and the optimization process to obtain the best formulation is described. Under the criteria of representativeness, verified with the advice of the IOC, aroma persistence, and simplicity in formulation, two RMs for winey-vinegary and rancid were obtained by diluting acetic acid and ethanol (winey-vinegary defect) and hexanal (rancid defect) together with other compounds that are used to modify aroma and avoid non-natural sensory notes.