bluuebunny/crossref_metadata_2025 huggingface dataset:
Visualizing the invisible tie: Linking parent–child neural synchrony to parents’ and children's attachment representations
Authors: Nguyen Trinh , Kungl Melanie T. , Hoehl Stefanie , White Lars O. , Vrtička Pascal
Published: March 2024

It is a central tenet of attachment theory that individual differences in attachment representations organize behavior during social interactions. Secure attachment representations also facilitate behavioral synchrony, a key component of adaptive parent–child interactions. Yet, the dynamic neural processes underlying these interactions and the potential role of attachment representations remain largely unknown. A growing body of research indicates that interpersonal neural synchrony (INS) could be a potential neurobiological correlate of high interaction and relationship quality. In this study, we examined whether interpersonal neural and behavioral synchrony during parent–child interaction is associated with parent and child attachment representations. In total, 140 parents (74 mothers and 66 fathers) and their children (age 5–6 years; 60 girls and 80 boys) engaged in cooperative versus individual problem‐solving. INS in frontal and temporal regions was assessed with functional near‐infrared spectroscopy hyperscanning. Attachment representations were ascertained by means of the Adult Attachment Interview in parents and a story‐completion task in children, alongside video‐coded behavioral synchrony. Findings revealed increased INS during cooperative versus individual problem solving across all dyads (𝛸2(2) = 9.37, p = 0.009). Remarkably, individual differences in attachment representations were associated with INS but not behavioral synchrony (p > 0.159) during cooperation. More specifically, insecure maternal attachment representations were related to higher mother–child INS in frontal regions (𝛸2(3) = 9.18, p = 0.027). Conversely, secure daughter attachment representations were related to higher daughter–parent INS within temporal regions (𝛸2(3) = 12.58, p = 0.006). Our data thus provide further indication for INS as a promising correlate to probe the neurobiological underpinnings of attachment representations in the context of early parent–child interactions.

Research Highlights

We assessed attachment representations using narrative measures and interpersonal neural synchrony (INS) during parent‐child problem‐solving.

Dyads including mothers with insecure attachment representations showed higher INS in left prefrontal regions.

Dyads including daughters with secure attachment representations showed higher INS in right temporo‐parietal regions.

INS is a promising correlate to probe the neurobiological underpinnings of attachment representations in the context of parent‐child interactions, especially within the mutual prediction framework.
Hospital‐based surveillance of children with cerebral palsy in Suriname: The Suriname cerebral palsy register
Authors: Declerck Marlies H. P. , Jahan Israt , Lissone Neirude P. A. , Walhain Fenna , Chin A Fat Ruby , Fleurkens Marianne , Muradin Sarfaraz H. J. , Cruden Rhea , Ortibus Els , Badawi Nadia , Khandaker Gulam
Published: March 2024

Aim

To describe the aetiological risk factors, clinical characteristics, access to rehabilitation, and educational status of children with cerebral palsy (CP) in Suriname.

Method

Hospital‐based surveillance of children with CP aged younger than 18 years was conducted at the Academic Hospital Paramaribo, Suriname (known as the Suriname CP Register [SUR‐CPR]). Data were collected on sociodemographic characteristics, aetiological risk factors, clinical characteristics, rehabilitation, and educational status. Registry data on aetiological risk factors were compared with available national prevalence rates in Suriname. Descriptive statistics were reported.

Results

Between August 2018 and March 2020, 82 children with CP (mean [SD] age 5 years 10 months [3 years 10 months]) attending the Academic Hospital Paramaribo were registered in the SUR‐CPR. The mean (SD) age at diagnosis was 5 years 5 months (4 years 1 month). Spastic CP was predominant in 90.8% of children and 58.8% were classified in Gross Motor Function Classification System levels III to V. Overall, 43.9% had preterm birth compared with 13.9% reported nationally (p < 0.001) and 61.6% had birth‐related complications compared with 15% reported nationally (p < 0.001). Additionally, 39.1% had birth asphyxia and 23.2% had early feeding difficulties. Sixty‐two percent were admitted to the neonatal intensive care unit, 54.0% of whom required ventilation. Most children (82.5%) had CP acquired pre‐ or perinatally and 17.5% had CP acquired postneonatally. Seventeen percent had never received any rehabilitation services, and 31.9% of the school‐aged children were not enrolled in any education system.

Interpretation: The high burden of known aetiological risk factors, delayed diagnosis, and severe functional impairment among children with CP registered at the Academic Hospital Paramaribo is concerning. Public health interventions targeting early diagnosis and early intervention could improve the functional outcome of children with CP in Suriname.

What this paper adds

Almost half of the children with cerebral palsy (CP) had preterm birth, low birthweight, and signs of birth asphyxia.

Most of the children were diagnosed after 5 years of age.

Overall, 52.5% of children had severe forms of CP of whom only 36.6% received any assistive devices.
Audit simulation and learning styles: Enhancing students' experiential learning and performance at a MENA university
Authors: Elsayed Nader , Hassan Mostafa Kamal
Published: March 2024

Drawing on experiential learning theory (ELT), this study (1) explores students' perceived benefits of experiencing different learning styles through an audit simulation (AS) assignment and (2) analyses its role in enhancing students' performance at a Middle East and North Africa (MENA) university. The study compares students' performance across two different periods, 2019 and 2022, with 46 and 48 participants, respectively, independently completing a questionnaire of six open‐ended questions paired with follow‐up feedback, the instructor's observations and the analyses of students' grades. Our study findings indicate that the AS assignment enabled students to effectively experience different learning styles at different times during the AS learning process. They visualised an authentic AS experience by critically analysing and practically evaluating AS documents while showing strong preferences for initiating new experiences. It also reveals an improvement in students' grades after the AS implementation. Our study has theoretical implications relating to cognitive and constructivist learning, learning transfer and ethics awareness, as well as practical implications in audit education, skill development, teamwork, professional development, auditors' evaluation and curriculum assessment in other disciplines than auditing.
Sociocultural barriers to outsourcing housework: Unraveling the non‐use of domestic services
Authors: Trübner Miriam , Nisic Natascha
Published: March 2024

The outsourcing of housework is broadly recognized as providing an impetus for increasing women's participation in the labor market and relieving the burdens of households with children and dual earners. Despite an objective need, demand for paid domestic services is low, even for households with sufficient financial resources. By drawing on a German survey of cohabiting couples aged between 30 and 60, we analyze households that have, to date, not used domestic services (N = 1479). Based on items about attitudes toward domestic services, we identify five distinct attitude profiles defined by diverse combinations and levels of sociocultural barriers to outsourcing housework, including gendered expectations, privacy concerns, aversion toward a servant culture, and trust and control issues. Our results establish that half of the sample exhibits scarcely any sociocultural aversion to the employment of domestic help. While some of these households report preferring to do housework within the family, households of higher social strata, in particular, express a need for external support, but are hindered by an insufficient supply of and access to appropriate paid domestic services. In contrast, the other half of the sample consists of subgroups of rejectors, revealing different levels of disapproval and normative‐moral profiles concerning outsourcing. Interestingly, complete rejectors are often found in low‐income households, indicating a strong connection between socioeconomic and sociocultural characteristics. The results highlight the potential for future developments within the domestic service sector to meet customers' normative and moral concerns.
Global cognition and executive functions of older adults with type 1 diabetes mellitus without dementia
Authors: Nagasawa Kaoru , Matsumura Kimio , Uchida Takayasu , Suzuki Yuya , Nishimura Akihiro , Okubo Minoru , Igeta Yukifusa , Kobayashi Tetsuro , Sakurai Takashi , Mori Yasumichi
Published: March 2024

Aims/Introduction

This study aimed to characterize the global cognition and executive functions of older adults with type 1 diabetes mellitus in comparison with type 2 diabetes mellitus.

Materials and Methods

This study included 37 patients with type 1 diabetes mellitus aged ≥65 years and 37 age‐ and sex‐matched patients with type 2 diabetes mellitus. Patients with dementia scoring <24 on the Mini‐Mental State Examination were excluded. General cognition, memory, classic, and practical executive function were investigated.

Results

Patients with type 1 diabetes mellitus demonstrated lower psychomotor speed scores on Trail Making Tests A and B (P < 0.001, P < 0.013) than those with type 2 diabetes mellitus. The dysexecutive syndrome behavioral assessment revealed similar results in patients with types 1 and 2 diabetes mellitus. The Wechsler Memory Scale‐Revised verbal episodic memory and Montreal Cognitive Assessment Japanese version were similar in terms of general cognition, but worse delayed recall subset on the latter was associated with type 2 diabetes mellitus (P = 0.038). A worse Trail Making Test‐A performance was associated with type 1 diabetes mellitus and age (P < 0.004, P < 0.029).

Conclusions

Executive function of psychomotor speed was worse in older outpatient adults without dementia with type 1 diabetes mellitus than in those with type 2 diabetes mellitus but with no significant differences in the comprehensive and practical behavioral assessment of dysexecutive syndrome. Patients with type 1 diabetes had more severely impaired executive function, whereas those with type 2 had greater impaired memory than executive function.
Voltinism and life‐history traits of the invasive fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) feeding on corn
Authors: Huang Li‐Li , Xue Fang‐Sen , Tang Jian‐Jun , Wu Shao‐Hui , He Hai‐Min
Published: March 2024

Voltinism and life‐history traits of the invasive fall armyworm (FAW) Spodoptera frugiperda were investigated under semi‐natural conditions for a period of 2 years. The FAW invaded the corn field in the suburbs of Nanchang (28°46′ N, 115°50′ E) in early summer and produced six complete generations. FAW had the characteristics of short developmental time, high survival rates and strong fecundity. The development time of female pupae was significantly faster than that of male pupae, resulting in the emergence of female pupae earlier than male pupae. Except for the sixth generation in 2021, there was no significant difference between female and male sex ratio, which was close to 1:1. FAW showed male‐bias sexual size dimorphism with male pupae being significantly larger than female pupae. Unlike pupal weight, in most generations, male adult weighed significantly less than females, because the weight loss of male pupae during metamorphosis was significantly greater than that of female pupae. The temporal variation of pupal weight did not conform to the temperature–size rule. Compared with 22.8°C, the 29.2°C high temperature not only significantly reduced the development time of larvae but also significantly increased pupal weight. The adult fecundity feeding on fresh corn leaves was higher than that feeding on live corn plants in most generations. In most generations, pupal weight was positively correlated with larval development time and adult weight was positively correlated with fecundity. In conclusion, climate differences between generations and years have significant effects on developmental time, body weight, sexual size dimorphism and fecundity of the FAW. These results add to the understanding of the evolution of life‐history traits in the FAW and may have important implications for predicting population dynamics of the FAW and optimising control strategies.
Testing the Relationship of Linguistic Complexity to Second Language Learners’ Comparative Judgment on Text Difficulty
Authors: Zhang Xiaopeng , Lu Xiaofei
Published: March 2024

This study examined the relationship of linguistic complexity, captured using a set of lexical richness, syntactic complexity, and discoursal complexity indices, to second language (L2) learners’ perception of text difficulty, captured using L2 raters’ comparative judgment on text comprehensibility and reading speed. Testing materials were 180 texts abridged from college English coursebooks, and raters were 90 advanced Chinese learners of L2 English. Forty‐five raters read paired texts and determined which text was harder to understand in each pair, and another 45 raters read paired texts and determined which text they read faster in each pair. Two stepwise linear regression models containing lexical, syntactic, and discoursal features explained 48.1% and 54.6% of the variance in L2 learners’ estimates of text comprehensibility and reading speed, respectively, outperforming four commonly used language readability models. These findings contribute useful insights into the relationship between linguistic complexity and L2 learners’ perception of text difficulty.
Autoencoder‐based method to assess bridge health monitoring data quality
Authors: Xiao Bowen , Di Jin , Wang Jie , Wu Guanliang , Shi Jiapeng , Wang Xiaohai , Fan Jiuhong
Published: March 2024

The data quality determines the reliability of big data‐based bridge condition assessments. However, rapidly discerning data conditions and identifying low‐quality data segments pose considerable challenges. This study introduces a transformer‐based autoencoder neural network for rapid data quality assessment in bridge health monitoring. The average Euclidean distance was used to quantify the dispersion of multiple hidden variables, and the overall quality of the multiple data fragments was quantitatively evaluated. Moreover, a method was introduced to calculate the adaptive thresholds based on the Euclidean distance. The application to the acceleration data of a cable‐stayed bridge demonstrates that the proposed method can extract hidden variables from acceleration data segments of length 3000. The network achieves a high compression rate of 1/1500, and the extracted hidden variables retain pertinent information regarding data quality. The proposed approach is data‐driven and exhibits significant advantages in efficiency, accuracy, and user‐friendliness.
Regulation of late‐acting operons by three transcription factors and a CRISPR‐Cas component during Myxococcus xanthus development
Authors: Saha Shreya , Kroos Lee
Published: March 2024

Upon starvation, rod‐shaped Myxococcus xanthus bacteria form mounds and then differentiate into round, stress‐resistant spores. Little is known about the regulation of late‐acting operons important for spore formation. C‐signaling has been proposed to activate FruA, which binds DNA cooperatively with MrpC to stimulate transcription of developmental genes. We report that this model can explain regulation of the fadIJ operon involved in spore metabolism, but not that of the spore coat biogenesis operons exoA‐I, exoL‐P, and nfsA‐H. Rather, a mutation in fruA increased the transcript levels from these operons early in development, suggesting negative regulation by FruA, and a mutation in mrpC affected transcript levels from each operon differently. FruA bound to all four promoter regions in vitro, but strikingly each promoter region was unique in terms of whether or not MrpC and/or the DNA‐binding domain of Nla6 bound, and in terms of cooperative binding. Furthermore, the DevI component of a CRISPR‐Cas system is a negative regulator of all four operons, based on transcript measurements. Our results demonstrate complex regulation of sporulation genes by three transcription factors and a CRISPR‐Cas component, which we propose produces spores suited to withstand starvation and environmental insults.
BALTIC AMBER IN HISPANIA DURING LATE ANTIQUITY. CONTACTS, NETWORKS AND EXCHANGE
Authors: Vallejo‐Casas Elena , Ripoll Gisela , Sánchez Romero Margarita , Murillo‐Barroso Mercedes
Published: March 2024

Amber is a material of great social value that has been identified at various archaeological sites on the Iberian peninsula dating to Late Antiquity. The objects, mostly necklace beads, have been discussed to date with limited results in relation to a small number of studies. This article presents the characterization by Fourier Transform Infrared Spectroscopy (FTIR) of 52 amber beads from four Late Antique necropolises in the province of Granada (south‐eastern Iberian peninsula): Cortijo del Chopo (Colomera), El Castillón (Montefrío), Marugán (Atarfe) and Fuente Santa (Loja). The results obtained demonstrate the Baltic origin of the amber at these sites and advance our knowledge of this type of product in Hispanic Late Antique funerary contexts.
Meta‐analysis of pulsed‐field ablation versus cryoablation for atrial fibrillation
Authors: Zhang Hehua , Zhang Hua , Lu Heng , Mao Yinjun , Chen Jianxing
Published: March 2024

Purpose

The available data on the treatment strategy of pulsed field ablation (PFA) for patients with atrial fibrillation (AF) is limited. This study aims to provide a comparative analysis of the efficacy, safety, and procedural efficiency between PFA and cryoballoon ablation (CBA) for AF.

Methods

We conducted a comprehensive search of the EMBASE, PubMed, Cochrane Library, and ClinicalTrials.gov databases to identify trials comparing PFA with CBA for AF from their inception until December 2023. The odds ratio (OR) and mean difference (MD), along with a 95% confidence interval (CI), were utilized as measures of treatment effect.

Results

The analysis included 15 eligible trials with a total enrollment of 1880 patients. No significant differences were found in recurrent atrial arrhythmia (OR 0.83, 95% CI 0.64, 1.07) or periprocedural complications (OR 0.78, 95% CI 0.46, 1.30) between the two ablation techniques examined in this study. However, the PFA technique demonstrated a significantly shorter procedure time (MD ‐7.17, 95% CI ‐13.60, ‐0.73), but a longer fluoroscopy time (MD 2.53, 95% CI 0.87, 4.19). Similarly, PFA was found to be significantly associated with a decreased incidence of phrenic nerve palsy (OR 0.20, 95% CI 0.07, 0.59), but an increased incidence of cardiac tamponade (OR 4.07, 95% CI 1.15, 14.39). Moreover, there was a significantly higher release of troponin with PFA compared to CBA (MD 470.28, 95% CI 18.89, 921.67), while the increase in S100 protein and heart rate was significantly lower with PFA than with CBA (MD ‐64.41, 95% CI ‐105.46, ‐17.36), (MD ‐8.76, 95% CI ‐15.12, ‐2.40).

Conclusion

The utilization of PFA provides a safer, time‐saving, and tissue‐specific procedure compared to CBA, while maintaining comparable success rates. This has the potential to enhance procedural efficiency and optimize resource utilization in clinical practice. These findings underscore the feasibility and promise of PFA as an alternative technique for PVI in patients with AF.
Controlling diurnal flower‐opening time by manipulating the jasmonate pathway accelerates development of indica–japonica hybrid rice breeding
Authors: Wang Mumei , Zhu Xiaopei , Huang Zhen , Chen Minghao , Xu Peng , Liao Shitang , Zhao Yongzhen , Gao Yannan , He Jiahui , Luo Yutong , Chen Huixuan , Wei Xiaoying , Nie Shuai , Dong Jingfang , Zhu Liya , Zhuang Chuxiong , Zhao Junliang , Liu Zhenlan , Zhou Hai
Published: March 2024

Inter‐subspecific indica–japonica hybrid rice (Oryza sativa) has the potential for increased yields over traditional indica intra‐subspecies hybrid rice, but limited yield of F1 hybrid seed production (FHSP) hinders the development of indica–japonica hybrid rice breeding. Diurnal flower‐opening time (DFOT) divergence between indica and japonica rice has been a major contributing factor to this issue, but few DFOT genes have been cloned. Here, we found that manipulating the expression of jasmonate (JA) pathway genes can effectively modulate DFOT to improve the yield of FHSP in rice. Treating japonica cultivar Zhonghua 11 (ZH11) with methyl jasmonate (MeJA) substantially advanced DFOT. Furthermore, overexpressing the JA biosynthesis gene OPDA REDUCTASE 7 (OsOPR7) and knocking out the JA inactivation gene CHILLING TOLERANCE 1 (OsHAN1) in ZH11 advanced DFOT by 1‐ and 2‐h respectively; and knockout of the JA signal suppressor genes JASMONATE ZIM‐DOMAIN PROTEIN 7 (OsJAZ7) and OsJAZ9 resulted in 50‐min and 1.5‐h earlier DFOT respectively. The yields of FHSP using japonica male‐sterile lines GAZS with manipulated JA pathway genes were significantly higher than that of GAZS wildtype. Transcriptome analysis, cytological observations, measurements of elastic modulus and determination of cell wall components indicated that the JA pathway could affect the loosening of the lodicule cell walls by regulating their composition through controlling sugar metabolism, which in turn influences DFOT. This research has vital implications for breeding japonica rice cultivars with early DFOT to facilitate indica–japonica hybrid rice breeding.
Genomic full‐length sequence of the novel HLA‐B*56:94 allele
Authors: Yang John Jeongseok , Oh Heung‐Bum
Published: March 2024

HLA‐B*56:94 differs from HLA‐B*56:05:01 by two non‐synonymous nucleotide substitutions in exon 1 and synonymous nucleotide substitutions in exon 1 and exon 2.
Toward a dual-species atom interferometer with cadmium and strontium
Authors: Tinsley J. N. , Bandarupally S. , Chiarotti M. , Manzoor S. , Sacco M. , Poli N.
Published: March 2024

We report on the progress toward a dual-species cadmium and strontium atom interferometer for fundamental physics tests. We have developed and characterized a complete baseline laser system for cadmium, which provides the high power and narrow linewidth necessary for laser cooling and trapping and for performing atom interferometry, with upgraded systems for strontium also implemented. An overview of a design for cooling cadmium is presented, and we outline the basic design of a Cd–Sr atomic fountain, discussing atom launching techniques and the possible role of blackbody radiation. The excellent properties of cadmium and strontium, both individually and as a test pair, are discussed along with the enabled fundamental physics program of tests of the weak equivalence principle and the measurement of relativistic time dilation effects in quantum superpositions of clocks.
The effect of native language and bilingualism on multimodal perception in speech: A study of audio-aerotactile integration
Authors: Saito Haruka , Tiede Mark , Whalen D. H. , Ménard Lucie
Published: March 2024

Previous studies of speech perception revealed that tactile sensation can be integrated into the perception of stop consonants. It remains uncertain whether such multisensory integration can be shaped by linguistic experience, such as the listener's native language(s). This study investigates audio-aerotactile integration in phoneme perception for English and French monolinguals as well as English-French bilingual listeners. Six step voice onset time continua of alveolar (/da/-/ta/) and labial (/ba/-/pa/) stops constructed from both English and French end points were presented to listeners who performed a forced-choice identification task. Air puffs were synchronized to syllable onset and randomly applied to the back of the hand. Results show that stimuli with an air puff elicited more “voiceless” responses for the /da/-/ta/ continuum by both English and French listeners. This suggests that audio-aerotactile integration can occur even though the French listeners did not have an aspiration/non-aspiration contrast in their native language. Furthermore, bilingual speakers showed larger air puff effects compared to monolinguals in both languages, perhaps due to bilinguals' heightened receptiveness to multimodal information in speech.
Comparative Analysis of Morphological Diversification in Large African Barbs of the Genus Barbus (Labeobarbus auctorum, Cyprinidae) and Altai Osmans of the Genus Oreoleuciscus (Leuciscidae)
Authors: Mina M. V. , Mironovsky A. N. , Dgebuadze Yu. Yu.
Published: March 2024

The study of diversity in characters of the skull in generalized and specialized morphotypes of the large African barbs Barbus (Labeobarbus auctorum) in Ethiopia is carried out using the multivariate analysis methods. It has been proven that in Lake Tana exhibiting great diversity in morphotypes, the eigenvector loadings on the first principal component of characters of bones, which form the jaws, compose a distinct self-standing cluster in specimens of a generalized form reaching over 15 cm in length. In barbs inhabiting other lakes, where only a generalized form is found, the lack of such cluster is observed, while the eigenvector loadings on the second principal component generate a cluster similar in composition. The same pattern is discovered in the Altai osmans (genus Oreoleuciscus) in Lake Orog within the Central Asian Closed Basin (Mongolia). In this case, however, the specimens of the generalized form tend to exhibit the characters of a bigmouth form after transition to feeding on fish whereas the progeny of bigmouth barbs in Lake Tana exhibit the parental characters even in the aquarium-based experiments. It is assumed that in the Altai osmans from Lake Orog we observe an early stage of morpho-ecological divergence between forms, when it is still reversible, while the divergence at a later stage, when it is irreversible, is detected in the barbs from Lake Tana, which may be regarded as an example of genetic assimilation.
Structural optimization design of connection between centrifugal impeller and shaft end based on finite element method
Authors: Li Yanjun , Ma Zhichao
Published: March 2024

A centrifugal compressor is the core equipment of the chemical industry. To solve the problems of assembly difficulties and poor mechanical properties caused by the connection between impeller and shaft end in existing compressor, this paper takes a small geared air compressor designed by Shenyang Borui Turbine Technical Service Co., Ltd. as an example and designs its first-stage impeller and shaft end into three structural forms of tie rod–pin connection, tie rod–end key connection, and flange connection, respectively, to find an optimal connection mode between the centrifugal impeller and shaft end. Firstly, the calculation method is verified. Then, the stress, strain, deformation, and critical rotor speed of these three structures are compared and analyzed based on multi-parameter genetic optimization method. The results show that when the impeller and shaft end are connected by the tie rod–end key structure, compared to the tie rod–pin connection structure and flange connection structure, the maximum stress is reduced by 43.8% and 61.2%, the strain is reduced by 43.8% and 61.8%, the deformation is reduced by 3.64 times and 6.27 times, respectively, and the resonance margin will also be greatly improved. The research results in this paper provide a theoretical basis for the reliable design of the connection between the centrifugal impeller and shaft end.
Quantum gate sets for lattice QCD in the strong-coupling limit: $N_{f}=1$
Authors: Fromm Michael , Philipsen Owe , Unger Wolfgang , Winterowd Christopher
Published: March 2024

We derive the primitive quantum gate sets to simulate lattice quantum chromodynamics (LQCD) in the strong-coupling limit with one flavor of massless staggered quarks. This theory is of interest for studies at non-zero density as the sign problem can be overcome using Monte Carlo methods. In this work, we use it as a testing ground for quantum simulations. The key point is that no truncation of the bosonic Hilbert space is necessary as the theory is formulated in terms of color-singlet degrees of freedom (“baryons” and “mesons”). The baryons become static in the limit of continuous time and decouple, whereas the dynamics of the mesonic theory involves two qubits per lattice site. Lending dynamics also to the “baryons” simply requires to use the derived gate set in its controlled version.
THE EFFECTS OF WORK-LIFE BALANCE, ORGANISATIONAL LEARNING CAPABILITY, AND TRANSFORMATIONAL LEADERSHIP ON PRODUCT INNOVATION PERFORMANCE
Authors: PICOLO JAIME DAGOSTIM , GIANCARLO GOMES , TONTINI GÉRSON , RODRIGUES JORGE JOSÉ MARTINS
Published: March 2024

This study significantly advances innovation management literature by analysing the impact of work-life balance (WLB), organisational learning capability (OLC), and transformational leadership (TL) on product innovation performance (PIP). By employing Partial Least Squares Structural Equation Modelling (PLS-SEM) combined with Necessary Condition Analysis (NCA), it clarifies the roles of these variables in Brazil’s manufacturing sector. Data from 332 organisations revealed that OLC and TL are vital for enhancing PIP, while WLB, though not directly influential, is crucial for innovation. This finding offers a new understanding of WLB’s role in innovation management and highlights the complexity of factors driving product innovation. Integrating NCA with PLS-SEM, this research enriches theoretical debates and provides practical insights for optimising innovation strategies. It fills a gap in the literature by analysing how these key factors interact to impact PIP, contributing to both academic research and practical innovation management.
Generative AI and CS Education
Authors: Johnson Maggie
Published: March 2024

Increasing knowledge sharing between industry and academia.
SIoV Mobility Management Using SDVN-Enabled Traffic Light Cooperative Framework
Authors: Kumar Neetesh , Singh Navjot , Sachan Anuj , Chaudhry Rashmi
Published: March 2024

Social Internet of Vehicles (SIoV) is an emerging connected vehicular networking framework among specialized social vehicles to share and disseminate important information like traffic updates, weather conditions, parking slots, so on. This study aims to form an SIoV network among emergency vehicles for their frequent communication to improve the throughput, average waiting time, queue length, and speed during vehicular movement while crossing the intersection in the city. To address this, we propose a novel Smart Traffic Light Controller (STLC)-assisted Software-Defined Vehicular Networking (SDNV)-enabled SIoV framework for emergency vehicles. Emergency vehicles form an SIoV network by utilizing SDVN architecture in vehicle-to-vehicle and vehicle-to-infrastructure communication. The SDVN module is used to offer two essential services: (1) SIoV-based road-lane prioritization and (2) congestion prevention signal generation for the STLC. An SDVN-MP algorithm is proposed to generate an effective traffic light control signal with an SDVN controller feedback signal. Furthermore, to improve the SIoV movement in the city, two levels of prioritization are done: (1) SIoV and (2) the road lane with SIoV. The first level of prioritization is to assign higher weightage to the social vehicular entities, and the second level is to prioritize the respective road lane based on SIoV quantity. The proposed framework is validated through a realistic simulation study on the Indian city OpenStreetMap utilizing the Simulation of Urban MObility simulator. The experimental findings demonstrate that the SDVN-MP model enhances (state-of-the-art) comparative performance by 22.5–55.2%, 1.2–82.7%, 1.6–38.4%, and 1.8–12.4% for average waiting time, average speed, average queue length, and average throughput metrics, respectively.
Apelin regulates skeletal muscle adaptation to exercise in a high-intensity interval training model
Authors: Kilpiö Teemu , Skarp Sini , Perjés Ábel , Swan Julia , Kaikkonen Leena , Saarimäki Samu , Szokodi István , Penninger Josef M. , Szabó Zoltán , Magga Johanna , Kerkelä Risto
Published: March 2024

Apelin levels decline with age. This study demonstrates that in trained mice, apelin deficiency results in a switch from fast type II myofibers to slow oxidative type I myofibers. This is associated with a concomitant change in gene expression profile toward fatty acid utilization, indicating an aged-muscle phenotype in exercised apelin-deficient mice. These data are of importance in the design of exercise programs for aging individuals and could offer therapeutic target to maintain muscle mass.
Effects of Different Astaxanthin Sources on Fillet Coloration and Energy Deposition in Rainbow Trout (Oncorhynchus mykiss)
Authors: Meng Xiaoxue , Yang Fumei , Zhu Lulu , Zhan Lingli , Numasawa Toru , Deng Junming
Published: March 2024

A 9‐week feeding trial was conducted to investigate the effects of different dietary sources of astaxanthin on fillet coloration, texture, and nutrient composition in rainbow trout (Oncorhynchus mykiss). Eight diets were formulated to contain 0, 25, 50, 75, 100, and 125 mg/kg astaxanthin from wall‐broken Haematococcus pluvialis (WBHPA), 100 mg/kg astaxanthin from wall‐unbroken H. pluvialis (WUHPA), or chemically synthesized astaxanthin (CSA). Each diet was fed to triplicate groups of rainbow trout (mean initial weight of 561 g) twice daily (07:00 and 17:00) to apparent satiation for 9 weeks. Results showed that at the 100 mg/kg astaxanthin inclusion level, the CAS group had higher fillet gross energy, dorsal fillet redness, and dorsal fillet color card score compared to the WBHPA‐100 group, with both being higher than the WUHPA group (P < 0.05). Fillet astaxanthin content, dorsal fillet yellowness, and lateral line redness and yellowness did not differ significantly between the CSA and WBHPA‐100 groups (P > 0.05), but were higher than the WUHPA group. When WBHPA was used, the inclusion of 50–100 mg/kg decreased fillet lightness but increased fillet redness, while better fillet texture was served at 75–125 mg/kg. Dietary 25–125 mg/kg WBHPA inclusion increased fillet astaxanthin and gross energy concentrations, with minor effects on fatty acid compositions of fillet. Inclusion of over 100 mg/kg astaxanthin regardless of source decreased fillet threonine and serine contents, and the WBHPA‐100 group had lower fillet glycine and alanine contents compared to the control group (P < 0.05). In conclusion, CSA had the most significant impact on fillet coloration and energy deposition in rainbow trout, while WUHPA had the least favorable effect. Additionally, the wall‐breaking treatment of H. pluvialis can improve the effect of astaxanthin on fillet coloration and nutrient composition in rainbow trout, with a recommended dose range of 75–100 mg/kg.
Table S2 from Spectral Flow Cytometry Methods and Pipelines for Comprehensive Immunoprofiling of Human Peripheral Blood and Bone Marrow
Authors: Spasic Milos , Ogayo Esther R. , Parsons Adrienne M. , Mittendorf Elizabeth A. , van Galen Peter , McAllister Sandra S.
Published: March 2024

Table S2. M/N/D Panel Reagents. Information and concentration of indicated fluorophore-conjugated antibodies used to label PBMCs in these studies.
TABLE 1 from Spectral Flow Cytometry Methods and Pipelines for Comprehensive Immunoprofiling of Human Peripheral Blood and Bone Marrow
Authors: Spasic Milos , Ogayo Esther R. , Parsons Adrienne M. , Mittendorf Elizabeth A. , van Galen Peter , McAllister Sandra S.
Published: March 2024

PBMC panels markers. Cell-surface markers used to gate and identify indicated cell types in PBMC samples
Figure S2 from Spectral Flow Cytometry Methods and Pipelines for Comprehensive Immunoprofiling of Human Peripheral Blood and Bone Marrow
Authors: Spasic Milos , Ogayo Esther R. , Parsons Adrienne M. , Mittendorf Elizabeth A. , van Galen Peter , McAllister Sandra S.
Published: March 2024

Figure S2. Unmixing Accuracy Assessment. NxN permutations showing density plots of the same marker on the x-axis and every other fluorochrome plotted on the y-axis. Plots were manually examined for accuracy of unmixing. (A) T/B panel; (B) M/N/D panel; (E, F) BMC panel. The same PBMC donor sample was used for (A and B) and data represent cells gated as singlets, non-RBC, and live cells. (C) Density plot of CD159c-BYG575 vs CD19-BYG710 after automated unmixing. (D) Density plot of CD159c-BYG575 vs CD19-BYG710 after applying additional manual compensation of -2.79 using the SpectroFlo compensation tool. (F) NxN plots after removing antibody aggregates in NovaFluor Blue 610-70S – CD19. (G) Antibody aggregates are manually removed through the use of a NOT gate in the aberrant population.
FIGURE 6 from Spectral Flow Cytometry Methods and Pipelines for Comprehensive Immunoprofiling of Human Peripheral Blood and Bone Marrow
Authors: Spasic Milos , Ogayo Esther R. , Parsons Adrienne M. , Mittendorf Elizabeth A. , van Galen Peter , McAllister Sandra S.
Published: March 2024

BMC panel harmony integration for sample-specific batch correction. A, UMAP coordinates generated from concatenated files of 50,000 CD45+, live, singlets from each of 3 BMC donors demonstrate clustering of cells in two-dimensional space (left); however, these data show a strong sample-specific batch effect (middle) and poor cell type-specific clustering (right). B, Following integration using Harmony, new UMAP coordinates are generated (left), the data from 3 donors colocalize (middle), and cells annotated as the same cell type cluster in two-dimensional space (right).
FIGURE 1 from Spectral Flow Cytometry Methods and Pipelines for Comprehensive Immunoprofiling of Human Peripheral Blood and Bone Marrow
Authors: Spasic Milos , Ogayo Esther R. , Parsons Adrienne M. , Mittendorf Elizabeth A. , van Galen Peter , McAllister Sandra S.
Published: March 2024

PBMC Panel 1: Gating strategy for T and B cells. Density plots of the gating strategy used to identify indicated PBMC cell types in the T/B panel. Arrows denote sequential steps in the gating strategy and are used to visualize the relationships across populations. Density plots represent 553,000 CD45+ live single cells from concatenation of events from all donors (n = 3).
FIGURE 3 from Identification of Nonfunctional Alternatively Spliced Isoforms of STING in Human Acute Myeloid Leukemia
Authors: Boda Akash R. , Liu Arthur J. , Castro-Pando Susana , Whitfield Benjamin T. , Molldrem Jeffrey J. , Al-Atrash Gheath , Di Francesco Maria Emilia , Jones Philip , Ager Casey R. , Curran Michael A.
Published: March 2024

Identification of STING germline and transcript variants in AML. A, Summary of sequencing results indicating identification of known STING variant alleles and novel spliced isoforms. B, Structure of STING genomic locus and annotated coding sequence maps for WT, STING-I3R, and STING-Ex4D. Identification and validation of STING-I3R allele in primary bone marrow aspirates (C) and in normal donors (D) using primers to selectively amplify WT or I3R STING alleles.
Long Non-Coding RNA RP11-252C15.1 Is a Potential Biomarker of Prognosis and Hallmark for Leukemogenesis in Children with B-Cell Precursor Acute Lymphoblastic Leukemia
Authors: Pan Lili , Zheng Yongzhi , Zheng Hao
Published: March 2024

Introduction: Improved understanding of the prognostic biomarkers associated with childhood acute lymphoblastic leukemia (ALL) is needed for accurate risk group stratification. This study aimed to identify potential long non-coding RNA (lncRNA) markers and evaluate their prognostic value in children with ALL. Methods: We selected 50 children with newly diagnosed ALL and 20 age-matched patients with idiopathic immune thrombocytopenia (controls). RNA sequencing was performed to identify differentially expressed lncRNAs between the ALL and control groups. Correlation analysis was performed to determine the relationships between candidate lncRNAs, clinical features, and the risk of leukemogenesis. Results: A total of 1,019 differentially expressed lncRNAs were identified between the ALL and control groups. Reverse transcriptase (RT-qPCR) revealed that lncRNA RP11-252C15.1 and lncRNA RP11-701P16.2 were significantly upregulated in patients with ALL. Furthermore, correlation analysis showed that lncRNA RP11-252C15.1 and lncRNA RP11-701P16.2 represent potential predictors of leukemogenesis; however, only lncRNA RP11-252C15.1 was associated with clinical features and outcome in children with B-cell precursor ALL (BCP-ALL). In vitro experiments confirmed that lncRNA RP11-252C15.1 was significantly overexpressed in BCP-ALL cell lines and promoted proliferation and repressed apoptosis in MHH-CALL-3 cells. Conclusion: lncRNA RP11-252C15.1 is a potential oncogene in BCP-ALL pathogenesis and a prognostic biomarker in children with BCP-ALL.
Classification of Retronychia: A Narrative Clinical Review
Authors: Lencastre André , Richert Bertrand
Published: March 2024

Background: A retronychia classification system is overdue considering the most recent publications. Using the keyword “retronychia”, publications with a narrative literature review were selected from PubMed/MEDLINE, EMBASE and Google Scholar, adding a few select papers. Summary: This article proposes a theoretical pathophysiological basis for retronychia. Several factors alter the clinical picture of retronychia: length and periodicity of backward displacement, duration of disease, intensity of paronychia, presence and type of nail stacking (polymeronychia), and remodeling of the nail apparatus (elevation of the proximal nail, nail bed shortening, retroversion of the distal nail fold and acquired malalignment). Key Messages: With these factors in mind, we propose a new classification system for retronychia: A standing for acute, O for ongoing, and C for chronic. We believe this easy system may increase the diagnostic acuity for the disease and its understanding.
Renal progenitors derived from urine for personalized diagnosis of kidney diseases
Authors: Mazzinghi Benedetta , Melica Maria Elena , Lasagni Laura , Romagnani Paola , Lazzeri Elena
Published: March 2024

Background: Chronic kidney disease affects 10% of the world population and it is associated with progression to end stage kidney disease and increased morbidity and mortality. The advent of multi-omics technologies has expanded our knowledge on the complexity of kidney diseases, revealing their frequent genetic etiology, particularly in young subjects. Genetic heterogeneity and drug screening require patient-derived disease models to establish a correct diagnosis and evaluate new potential treatments and outcome.
Summary: Patient-derived renal progenitors can be isolated from urines to set up proper disease modeling. This strategy allows to make diagnosis of genetic kidney disease in patients carrying unknown significance variants or uncover variants missed from peripheral blood analysis. Furthermore, urinary-derived tubuloids obtained from renal progenitors of patients appear to be potentially valuable for modeling kidney diseases to test ex vivo treatment efficacy or to develop new therapeutic approaches. Finally, renal progenitors derived from urine can provide insights into acute kidney injury and predict kidney function recovery and outcome.
Key messages: Renal progenitors derived from urine are a promising new non-invasive and easy-to-handle tool, which improves the rate of diagnosis and the therapeutic choice, paving the way toward a personalized healthcare.
Teachers’ commitment and leadership behavior as correlates of academic performance
Authors: Ligaya Massuline Antonio D. , Ham Joung-hyun , Daniel Nanje Bakoma
Published: March 2024

This study examined the relationship between students’ academic performance, teachers’ commitment, and leadership behavior of school administrators. Teachers’ commitment was measured in two areas–commitment to job and commitment to organization and the leadership behavior of school administrators were evaluated in terms of consideration and initiating structure. Eighty-one teachers, 11 school heads, and 470 students served as respondents. The descriptive survey research technique, correlation analysis, and the following statistical methods were used: frequency, mean, standard deviation, and correlation coefficient. The study revealed that the initiating structure and consideration dimensions of leadership behavior affect teachers’ commitment to job (CTJ) and teacher’s commitment to organization (CTO). The correlation between CTJ and CTO and leadership behavior-initiating structure is positive and with leadership behavior-consideration negative. CTJ and CTO is correlated with the students’ academic performance in math, but not in Science and English. The correlation is negative. Students’ academic performance in all subject areas is negatively correlated with leadership behavior-initiating structure and has no significant relationship with leadership behavior-consideration. The leadership behavior-initiating structure is positively correlated with teachers’ commitment to both job and organization but has negative correlation with students’ academic performance in math, science, and English.
Preservice mathematics teacher knowledge of higher order thinking skills
Authors: Nenohai Juliana Mehelina Herlince , Dao Samo Damianus , Garak Siprianus Suban , Rimo Imelda Hendriani Eku , Soko Imelda Paulina
Published: March 2024

This study aims to describe preservice mathematics teacher knowledge of higher order thinking skills in terms of definition, Bloom's taxonomy level, curriculum, learning, and evaluation. This research is quantitative research with a survey method. and sample consisted of 248 preservice mathematics teachers in semesters VI - VIII of the Department of Mathematics Education, Nusa Cendana University, Timor University, and Wira Wacana Sumba University. The instrument used was a questionnaire about high order thinking skill (HOTS) which consisted of 105 statements. Data analysis used Likert's summeted rating, one sample test, Mann Whitney, Kruskall-Wallis tests, multiple linear regression test, and multivariate analyisis of variance (MANOVA) test. The results showed that the knowledge level of preservice mathematics teacher was in the good category. Based on gender differences, there was no significant difference in the average knowledge of preservice mathematics teacherabout HOTS, there was a significant difference in the average knowledge of preservice mathematics teacher about HOTS which is significant based on differences in academic ability and gender differences do not significantly affect knowledge about HOTS levels in Bloom's taxonomy, curriculum, and pedagogy while academic knowledge has a significant effect on HOTS knowledge of preservice teachers in almost all aspects except for pedagogy.