bluuebunny/crossref_metadata_2025 huggingface dataset:
Congenital Cytomegalovirus Severity Definitions and Treatment Decisions around the World: A Systematic Scoping Review of the Literature
Authors: Boscarino Giovanni , Romano Rossana , Tegoni Francesca , Iotti Carlotta , Perrone Serafina , Esposito Susanna , Buonsenso Danilo
Published: October 2024

Congenital cytomegalovirus (cCMV) is the most common cause of congenital infection and the leading cause of non-genetic sensorineural hearing loss in childhood. While treatment trials have been conducted in symptomatic children, defining asymptomatic infection can be complex. We performed a scoping review to understand how infection severity is defined and treated globally, as well as the various indications for initiating treatment. We conducted an electronic search of MEDLINE, EMBASE, Scopus, and the Cochrane Library, using combinations of the following terms: “newborn”, “baby”, “child”, “ganciclovir”, “valganciclovir”, and “cytomegalovirus” or “CMV”. We included eligible prospective and retrospective studies, case series, and randomized clinical trials (RCTs) published up to May 2024. A total of 26 studies were included, of which only 5 were RCTs. There was significant heterogeneity between studies. The most commonly considered criteria for symptomatic infection were microcephaly (23/24 studies), abnormal neuroimaging (22/24 studies), chorioretinitis/ocular impairment (21/24 studies), and hearing impairment (20/24 studies). Two studies also included asymptomatic newborns in their treatment protocols. Outcome measures varied widely, focusing either on different hearing assessments or neurocognitive issues. Our literature analysis revealed significant variability and heterogeneity in the definition of symptomatic cCMV infection and, consequently, in treatment approaches. A consensus on core outcomes and well-conducted RCTs are needed to establish treatment protocols for specific groups of newborns with varying manifestations of cCMV.
Valorization of Eggshell as Renewable Materials for Sustainable Biocomposite Adsorbents—An Overview
Authors: Babalola Bolanle M. , Wilson Lee D.
Published: October 2024

The production and buildup of eggshell waste represents a challenge and an opportunity. The challenge is that uncontrolled disposal of generated eggshell waste relates to a sustainability concern for the environment. The opportunity relates to utilization of this biomass resource via recycling for waste valorization, cleaner production, and development of a circular economy. This review explores the development of eggshell powder (ESP) from eggshell waste and a coverage of various ESP composite sorbents with an emphasis on their potential utility as adsorbent materials for model pollutants in solid–liquid systems. An overview of literature since 2014 outlines the development of eggshell powder (ESP) and ESP composite adsorbents for solid–liquid adsorption processes. The isolation and treatment of ESP in its pristine or modified forms by various thermal or chemical treatments, along with the preparation of ESP biocomposites is described. An overview of the physico-chemical characterization of ESP and its biocomposites include an assessment of the adsorption properties with various model pollutants (cations, anions, and organic dyes). A coverage of equilibrium and kinetic adsorption isotherm models is provided, along with relevant thermodynamic parameters that govern the adsorption process for ESP-based adsorbents. This review reveals that ESP biocomposite adsorbents represent an emerging class of sustainable materials with tailored properties via modular synthetic strategies. This review will serve to encourage the recycling and utilization of eggshell biomass waste and its valorization as potential adsorbent systems. The impact of such ESP biosorbents cover a diverse range of adsorption-based applications from environmental remediation to slow-release fertilizer carrier systems in agricultural production.
Visual Navigation Systems for Maritime Smart Ships: A Survey
Authors: Wang Yuqing , Chen Xinqiang , Wu Yuzhen , Zhao Jiansen , Postolache Octavian , Liu Shuhao
Published: October 2024

The rapid development of artificial intelligence has greatly ensured maritime safety and made outstanding contributions to the protection of the marine environment. However, improving maritime safety still faces many challenges. In this paper, the development background and industry needs of smart ships are first studied. Then, it analyzes the development of smart ships for navigation from various fields such as the technology industry and regulation. Then, the importance of navigation technology is analyzed, and the current status of key technologies of navigation systems is deeply analyzed. Meanwhile, this paper also focuses on single perception technology and integrated perception technology based on single perception technology. As the development of artificial intelligence means that intelligent shipping is inevitably the trend for future shipping, this paper analyzes the future development trend of smart ships and visual navigation systems, providing a clear perspective on the future direction of visual navigation technology for smart ships.
Large-Scale Triaxial Test on Mechanical Behavior of Coral Sand Gravel Layered Samples
Authors: Tang Xinyue , Xin Dongfeng , Lei Xuewen , Yao Ting , Meng Qingshan , Liu Qingbing
Published: October 2024

Layered structures comprising coral sand and gravel have been observed in hydraulic filled foundations in the coral reefs in the South China Sea, leading to anisotropy in their physical and mechanical properties. However, the effect of a layered structure on the strength and deformation of the coral soil foundation remains unclear. In this study, a series of large-scale triaxial compression tests and step-loading tests were carried out on four types of samples, i.e., clean coral sand, clean coral gravel, sand-over-gravel layered sample, and gravel-over-sand layered sample, to investigate the impact of confining pressure and the layered structure on the strength and failure modes of these soils. The results indicate that the stress–strain relationships of all samples predominantly exhibit strain hardening under drained conditions. Under identical confining pressures, the peak strength of clean coral sand is the lowest, while that of coral gravel is the highest. The peak strengths of the two layered samples fall between these extremes, with the gravel-over-sand layered sample exhibiting higher strength. All four samples have similar peak friction angles, slightly exceeding 40°. The difference in peak strength among the four types of samples is attributed to the variations in cohesion, with the cohesion of clean coral gravel being up to four times that of clean sand, and the cohesion of layered samples falling between these two. Both clean sand and clean gravel samples exhibit a bulging phenomenon in the middle, while the layered samples primarily exhibit bulging near the coral gravel layer. In the step-loading tests, the bearing capacity of the layered samples falls between those of clean coral sand and coral gravel, with the gravel-over-sand layered samples demonstrating higher strength. Moreover, the p-s curve of the gravel-over-sand layered samples obtained from the large-scale triaxial apparatus under a confining pressure of 400 kPa resembles that from the plate load tests on the same samples.
Alleviation of NaCl Stress on Growth and Biochemical Traits of Cenchrus ciliaris L. via Arbuscular Mycorrhizal Fungi Symbiosis
Authors: Malik Jahangir A. , Alqarawi Abdulaziz A. , Alotaibi Fahad , Habib Muhammad M. , Sorrori Salah N. , Almutairi Majed B. R. , Dar Basharat A.
Published: October 2024

Soil salinization, especially in arid and semi-arid regions, is one of the major abiotic stresses that affect plant growth. To mediate and boost plant tolerance against this abiotic stress, arbuscular mycorrhizal fungi (AMF) symbiosis is commonly thought to be an effective tool. So, the main purpose of this study was to estimate the role of AMF (applied as a consortium of Claroideoglomus etunicatum, Funneliformis mosseae, Rhizophagus fasciculatum, and R. intraradices species) symbiosis in mitigating deleterious salt stress effects on the growth parameters (shoot length (SL), root length (RL), shoot dry weight (SDW), root dry weight (RDW), root surface area (RSA), total root length (TRL), root volume (RV), root diameter (RD), number of nodes and leaves) of Cenchrus ciliaris L. plants through improved accumulations of photosynthetic pigments (chlorophyll a, chlorophyll b, total chlorophyll), proline and phenolic compounds. The results of this experiment revealed that the roots of C. ciliaris plants were colonized by AMF under all the applied salinity levels (0, 75, 150, 225, and 300 mM NaCl). However, the rate of colonization was negatively affected by increasing salinity as depicted by the varied colonization structures (mycelium, vesicles, arbuscules and spores) which were highest under non-saline conditions. This association of AMF induced an increase in the growth parameters of the plant which were reduced by salinity stress. The improved shoot/root indices are likely due to enhanced photosynthetic activities as the AMF-treated plants showed increased accumulation of pigments (chlorophyll a, chlorophyll b and total chlorophyll), under saline as well as non-saline conditions, compared to non-AMF (N-AMF) plants. Furthermore, the AMF-treated plants also exhibited enhanced accumulation of proline and phenolic compounds. These accumulated metabolites act as protective measures under salinity stress, hence explaining the improved photosynthetic and growth parameters of the plants. These results suggest that AMF could be a good tool for the restoration of salt-affected habitats. However, more research is needed to check the true efficacy of different AMF inoculants under field conditions.
Alkali Activation of Metakaolin and Wollastonite: Reducing Sodium Hydroxide Use and Enhancing Gel Formation through Carbonation
Authors: Viola Veronica , Allah Prince , Perumal Priyadharshini , Catauro Michelina
Published: October 2024

Alkali activated materials (AAMs) offer significant advantages over traditional materials like Portland cement, but require the use of strong alkaline solutions, which can have negative environmental impacts. This study investigates the synthesis of AAMs using metakaolin and wollastonite, aiming to reduce environmental impact by eliminating sodium silicate and using only sodium hydroxide as an activator. The hypothesis is that wollastonite can provide the necessary silicon for the reaction, with calcium from wollastonite potentially balancing the negative charges usually countered by sodium in the alkaline solution. This study compares raw and carbonated wollastonite (AAM-W and AAM-CW) systems, with raw materials carefully characterized and binding networks analyzed using TGA, FT-IR, and XRD. The results show that while wollastonite can reduce the amount of sodium hydroxide needed, this reduction cannot exceed 50%, as higher substitution levels lead to an insufficiently alkaline environment for the reactions. The carbonation of wollastonite enhances the availability of silicon and calcium, promoting the formation of both N-A-S-H and C-A-S-H gels.
Innovative Hemp Shive-Based Bio-Composites: Part I: Modification of Potato Starch Binder by Sodium Meta-Silicate and Glycerol
Authors: Vitola Laura , Pundiene Ina , Pranckeviciene Jolanta , Bajare Diana
Published: October 2024

The growing demand for sustainable building materials has boosted research on plant-based composite materials, including hemp shives bound with biodegradable binders. This study investigates the enhancement of potato-starch-based binders with sodium metasilicate and glycerol to produce eco-friendly bio-composites incorporating hemp shives. Potato starch, while renewable, often results in suboptimal mechanical properties and durability in its unmodified form. The addition of sodium metasilicate is known to improve the mechanical strength and thermal stability of starch-based materials, while glycerol acts as a plasticizer, potentially enhancing flexibility and workability. Bio-composites were produced with varying concentrations of sodium metasilicate (0–107% by mass of starch) and glycerol (0–133% by mass of starch), and their properties were evaluated through thermal analysis, density measurements, water absorption tests, compressive strength assessments, and thermal conductivity evaluations. The results demonstrate that sodium metasilicate significantly increases the bulk density, water resistance, and compressive strength of the bio-composites, with enhancements up to 19.3% in density and up to 2.3 times in compressive strength. Glycerol further improves flexibility and workability, though excessive amounts can reduce compressive strength. The combination of sodium metasilicate and glycerol provides optimal performance, achieving the best results with an 80% sodium metasilicate and 33% glycerol mixture by weight of starch. These modified bio-composites offer promising alternatives t2 o conventional building materials with improved mechanical properties and environmental benefits, making them suitable for sustainable construction applications.
Maximising Synergy: The Benefits of a Joint Implementation of Knowledge Management and Artificial Intelligence System Standards
Authors: Khazieva Natalia , Pauliková Alena , Chovanová Henrieta Hrablik
Published: October 2024

Implementing management systems in organisations of all types and sizes often raises the following question: “What benefits will this bring?” Initial resistance and criticism are common as potential challenges are identified during the implementation process. To address this, it is essential to highlight the advantages of these systems and engage stakeholders in supporting management efforts. While the planning, implementation, use, maintenance, auditing, and improvement of management systems are generally voluntary, certification is frequently driven by external factors, particularly customer demands. Employees also stand to gain significantly, with knowledge and information serving as valuable resources, especially for leveraging artificial intelligence. This article explores the management’s readiness to adopt and fully utilise two management systems based on international standards: the ISO 30401 Knowledge management system (KMS) and the ISO/IEC 42001 Artificial intelligence management system (AIMS). Through interviews, we assess the challenges and solutions associated with implementing these systems, whether planned or partially adopted. The findings illustrate the synergistic benefits of integrating the KMS and AIMS, demonstrating how their combined use can enhance Integrated Management Systems (IMSs). Such integration supports comprehensive planning, operation, and performance evaluation of processes and services while also promoting continuous improvement.
An Investigation of Thermomechanical Behavior in Laser Hot Wire Directed Energy Deposition of NAB: Finite Element Analysis and Experimental Validation
Authors: Hatala Glenn W. , Reutzel Edward , Wang Qian
Published: October 2024

Laser Hot Wire (LHW) Directed Energy Deposition (DED) Additive Manufacturing (AM) processes are capable of manufacturing parts with a high deposition rate. There is a growing research interest in replacing large cast Nickel Aluminum Bronze (NAB) components using LHW DED processes for maritime applications. Understanding thermomechanical behavior during LHW DED of NAB is a critical step towards the production of high-quality NAB parts with desired performance and properties. In this paper, finite element simulations are first used to predict the thermomechanical time histories during LHW DED of NAB test coupons with an increasing geometric complexity, including single-layer and multilayer depositions. Simulation results are experimentally validated through in situ measurements of temperatures at multiple locations in the substrate as well as displacement at the free end of the substrate during and immediately following the deposition process. The results in this paper demonstrate that the finite element predictions have good agreement with the experimental measurements of both temperature and distortion history. The maximum prediction error for temperature is 5% for single-layer samples and 6% for multilayer samples, while the distortion prediction error is about 12% for single-layer samples and less than 4% for multilayer samples. In addition, this study shows the effectiveness of including a stress relaxation temperature at 500 °C during FE modeling to allow for better prediction of the low cross-layer accumulation of distortion in multilayer deposition of NAB.
Surface Engineering of Ti6Al4V: Impact of Rhenium–Carbon Coatings with Molybdenum Anchors on Biocompatibility and Corrosion Behavior
Authors: Orozco-Hernández Giovany , Mosquera-Diaz Sara V. , Ramírez-Monroy Juliana V. , Aperador Willian , Corredor-Figueroa Adriana P. , Pineda-Triana Yaneth
Published: October 2024

Titanium alloys, particularly Ti6Al4V, are widely used in biomedical applications due to their excellent mechanical properties and inherent biocompatibility. However, enhancing their surface characteristics, such as biocompatibility and corrosion resistance, remains a key challenge for their long-term use in medical implants. In this study, we investigate the effects of rhenium–carbon coatings deposited on Ti6Al4V substrates via magnetron sputtering, incorporating a molybdenum anchoring layer. X-ray diffraction (XRD) and energy dispersive spectroscopy (EDS) analyses confirmed the formation of rhenium carbides, elemental rhenium, and rhenium oxides within the coatings. Despite these successful depositions, scanning electron microscopy (SEM) revealed significant delamination and poor adhesion of the coatings to the Ti6Al4V substrates. Corrosion resistance, evaluated through potentiodynamic polarization tests, showed an increase in corrosion current densities and more negative corrosion potentials, indicating a detrimental effect on the substrate’s corrosion resistance. Biocompatibility assessments using PK15 cells demonstrated a marked decrease in cell viability and metabolic activity, particularly in samples with higher surface roughness. These findings underscore the critical need for the optimization of surface preparation and deposition processes to improve both the adhesion and biocompatibility of rhenium–carbon coatings on Ti6Al4V substrates. Future research should aim to refine coating technique to enhance adhesion, explore the mechanisms of cytotoxicity related to surface roughness, and expand biocompatibility studies across different cell lines and biological environments.
Drimia maritima as a New Green Inhibitor for Al-Si Alloy, SAE Steel and Pure Al Samples in 0.5 M NaCl Solution: Polarization and Electrochemical Impedance Analyses
Authors: Bonatti Rodrigo S. , Costa Diego , Padilha Giovana S. , Bortolozo Ausdinir D. , Osório Wislei R.
Published: October 2024

The corrosion inhibition effects of Drimia maritima (L.) Stearn sin. Urginea maritima (L.) Backer on three different materials, i.e., as-cast Al-7 wt.% Si alloy, SAE 1020 low carbon steel, and commercially pure Al samples, into a stagnant and naturally aerated 0.5 M NaCl solution are evaluated. For this purpose, both the potentiodynamic polarization curves and electrochemical impedance spectroscopy with an equivalent circuit are utilized. It is found that inhibition effect increases up to certain minor Drimia maritima content. Adsorption isotherms (e.g., Langmuir and Temkin) indicate that all three examined materials comprise physical adsorption mechanisms. Al-Si alloys attained inhibition efficiencies of about 96% at 25 °C with 1250 ppm of Drimia maritima and ~43% with 625 ppm at 45 °C. On the other hand, the cp. Al and SAE 1020 samples attain ~89% and 68% with 1250 ppm and 500 ppm at 25 °C, respectively. This clearly indicates that the dosage of Drimia maritima green inhibitor into NaCl solution possesses certain susceptibility for each distinctive material examined. Impedance parameters obtained by using CNLS (complex non-linear least squares simulations) are correlated and discussed.
Wheat Peptides as Catalysts for Athletic Performance Improvement in Cross-Country Skiers: A Randomized Controlled Trial
Authors: Xiang Mai , Han Qi , Chen Yue , Duan Shenglin , Han Xiaofeng , Sui Xuemei , Ren Chaoxue , Wang Qirong
Published: October 2024

Objectives: This study investigated the efficacy of wheat peptide supplementation compared to regular proteins in elite cross-country skiers, providing insights into the metabolic and performance effects of these supplements in order to guide athletes in selecting optimal energy sources for training and competition. Methods: Nineteen healthy male cross-country skiers were enrolled and assigned to either the peptide group (PEP, n = 9) or the protein group (PRO, n = 10). A four-week intervention study involving supplementation with wheat peptides/regular proteins was conducted, and pre- and post-intervention assessments were performed to evaluate exercise capacity and metabolic profiles. Results: The study found that the PEP group and the PRO group showed distinct within-group effects on exercise performance. The PEP group demonstrated improved aerobic capacity, including better performance in 10 km roller skating, an increased lactate threshold, and reduced resting blood lactate levels. The PRO group enhanced anaerobic capacity, such as improved sprint time, hexagon test performance, and lactate clearance. Metabolomic analysis revealed specific metabolic pathways affected in each group, with the PEP group showing impacts on the α-linolenic acid pathway and the PRO group on ketone body synthesis and degradation as well as vitamin B6 metabolism. Conclusions: Our findings indicate that wheat oligopeptides and regular proteins have comparable effects on exercise performance. However, the wheat peptides may offer greater advantages in enhancing aerobic capacity. No significant variations were observed in blood metabolite profiles between the two groups, but distinct metabolic pathways exhibited different responses.
Prenylated Dihydroflavonol from Sophora flavescens Regulate the Polarization and Phagocytosis of Macrophages In Vitro
Authors: Su Lu , Rao Kairui , Wang Lizhong , Pu Li , Zhang Zhijun , Li Hongmei , Li Rongtao , Liu Dan
Published: October 2024

As an important member of innate immunity, macrophages show remarkable plasticity and heterogeneity, and play an important role in immune regulation, tissue development, homeostasis of the internal environment and injury repair. However, the excessive activation of macrophages is closely related to the occurrence and development of many diseases. The prenylated flavonoid structure is one of the characteristic structures isolated from Sophora flavescens, with anti-inflammatory, anti-tumor, anti-allergy and other effects. In this study, the effects of (2R)-3β,7,4′-trihydroxy-5-methoxy-8-prenylflavanone (TMP), a prenylated dihydroflavonol, on the polarization and phagocytosis of macrophages were systematically studied. In LPS-induced M1-type macrophages, TMP dose-dependently inhibited the expression of COX-2, iNOS and the secretion of NO, IL-1β, IL-6 and IL-18, showing an inhibitory effect on M1 polarization. Further experiments revealed that it was related to the inhibition of TLR4-related AKT/mTOR, MAPK and NF-κB signaling pathways; in IL-4-induced M2-type macrophages, TMP down-regulated the expression of M2-related Arg1, IL-10, TGF-β, CD206 and CD163, as well as the phosphorylation levels of AKT1 and STAT6. For macrophages in a physiological state, it was very important for cells to return from a stress state to a phenotypic stability in the M0 state. These results indicated that TMP negatively regulated the M1/M2 polarization of macrophages, and made them tend to M0 homeostasis, which might provide new theoretical and data support for explaining the anti-inflammatory immunoregulatory activity of Sophora flavescens.
Healing Activity of Propolis of Stingless Bee (Scaptotrigona aff. postica), Reared in Monoculture of Açaí (Euterpe oleracea), in Induced Wounds in Rats
Authors: Ferreira Sara R. L. , Teixeira Suzanne A. , Lima Gabriella O. , de Castro Jhennifer N. R. S. , Teixeira Luís E. O. , Barros Carlos A. R. , Pereira Daniel S. , Hamoy Moisés , Bahia Veronica R. L. O. , Muto Nilton A.
Published: October 2024

Wound healing is a complex and coordinated process involving interactions between cells and various messenger systems. This study conducted in vivo tests to determine the healing effect of propolis (PR)-based cream derived from the Amazon stingless bee, Scaptotrigona aff. postica, reared in açaí (Euterpe oleracea) monoculture, on induced wounds in rats. Data were obtained by monitoring injuries on 14 Wistar rats, divided into three groups (G1, G2 and G3), each receiving specific treatments: propolis-based cream (PR), collagenase (PC) and neutral cream (NC). Over the seven days of treatment, the lesions were measured using photographic records and ImageJ software to evaluate the healing effectiveness of the test cream. ImageJ software version 1.53g was used to compare the wound diameters for each treatment. After seven days, histopathological analyses of the induced lesions were performed. It was observed that collagenase (PC) and the test cream (PR) did not differ significantly in terms of wound diameter reduction. However, the propolis-based cream directly influenced the lesion maturation process and exhibited a milder inflammatory response compared to the positive control (PC). This effect is possibly associated with antimicrobial and anti-inflammatory compounds identified by GC/MS analysis in the propolis. Notably, this is the first report describing propolis of Scaptotrigona aff. postica obtained from açaí monocultures with strong healing potential, highlighting the identification of a high concentration of phenolic compounds that aid directly in wound repair.
Artifacts and Anomalies in Raman Spectroscopy: A Review on Origins and Correction Procedures
Authors: Vulchi Ravi teja , Morgunov Volodymyr , Junjuri Rajendhar , Bocklitz Thomas
Published: October 2024

Raman spectroscopy, renowned for its unique ability to provide a molecular fingerprint, is an invaluable tool in industry and academic research. However, various constraints often hinder the measurement process, leading to artifacts and anomalies that can significantly affect spectral measurements. This review begins by thoroughly discussing the origins and impacts of these artifacts and anomalies stemming from instrumental, sampling, and sample-related factors. Following this, we present a comprehensive list and categorization of the existing correction procedures, including computational, experimental, and deep learning (DL) approaches. The review concludes by identifying the limitations of current procedures and discussing recent advancements and breakthroughs. This discussion highlights the potential of these advancements and provides a clear direction for future research to enhance correction procedures in Raman spectral analysis.
Enhancing Electrochemical Performance of Si@CNT Anode by Integrating SrTiO3 Material for High-Capacity Lithium-Ion Batteries
Authors: Oli Nischal , Liza Castillo Diana C. , Weiner Brad R. , Morell Gerardo , Katiyar Ram S.
Published: October 2024

Silicon (Si) has attracted worldwide attention for its ultrahigh theoretical storage capacity (4200 mA h g−1), low mass density (2.33 g cm−3), low operating potential (0.4 V vs. Li/Li+), abundant reserves, environmentally benign nature, and low cost. It is a promising high-energy-density anode material for next-generation lithium-ion batteries (LIBs), offering a replacement for graphite anodes owing to the escalating energy demands in booming automobile and energy storage applications. Unfortunately, the commercialization of silicon anodes is stringently hindered by large volume expansion during lithiation–delithiation, the unstable and detrimental growth of electrode/electrolyte interface layers, sluggish Li-ion diffusion, poor rate performance, and inherently low ion/electron conductivity. These present major safety challenges lead to quick capacity degradation in LIBs. Herein, we present the synergistic effects of nanostructured silicon and SrTiO3 (STO) for use as anodes in Li-ion batteries. Si and STO nanoparticles were incorporated into a multiwalled carbon nanotube (CNT) matrix using a planetary ball-milling process. The mechanical stress resulting from the expansion of Si was transferred via the CNT matrix to the STO. We discovered that the introduction of STO can improve the electrochemical performance of Si/CNT nanocomposite anodes. Experimental measurements and electrochemical impedance spectroscopy provide evidence for the enhanced mobility of Li-ions facilitated by STO. Hence, incorporating STO into the Si@CNT anode yields promising results, exhibiting a high initial Coulombic efficiency of approximately 85%, a reversible specific capacity of ~800 mA h g−1 after 100 cycles at 100 mA g−1, and a high-rate capability of 1400 mA g−1 with a capacity of 800 mA h g−1. Interestingly, it exhibits a capacity of 350 mAh g−1 after 1000 lithiation and delithiation cycles at a high rate of 600 mA hg−1. This result unveils and sheds light on the design of a scalable method for manufacturing Si anodes for next-generation LIBs.
Optimizing NiFe-Modified Graphite for Enhanced Catalytic Performance in Alkaline Water Electrolysis: Influence of Substrate Geometry and Catalyst Loading
Authors: Kuczyński Mateusz , Mikołajczyk Tomasz , Pierożyński Bogusław , Karczewski Jakub
Published: October 2024

The oxygen evolution reaction (OER) and the hydrogen evolution reaction (HER) are critical processes in water splitting, yet achieving efficient performance with minimal overpotential remains a significant challenge. Although NiFe-based catalysts are widely studied, their performance can be further enhanced by optimizing the interaction between the catalyst and the substrate. Here, we present a detailed investigation of NiFe-modified graphite electrodes, comparing the effects of compressed and expanded graphite substrates on catalytic performance. Our study reveals that substrate geometry plays a pivotal role in catalyst distribution and activity, with expanded graphite facilitating more effective electron transfer and active site utilization. Additionally, we observe that increasing the NiFe loading leads to only modest gains in performance, due to catalyst agglomeration at higher loadings. The optimized NiFe–graphite composites exhibit superior stability and catalytic activity, achieving lower overpotentials and higher current densities, making them promising candidates for sustainable hydrogen production via alkaline electrolysis.
The Satiating Effect of Extruded Plant Protein Compared with Native Plant and Meat Protein in a Ragú “Bolognaise” Meal: A Randomized Cross-Over Study
Authors: Martin Mille Skov , Dynesen Anja Weirsøe , Petersen Birthe , Petersen Iben Lykke , Duque-Estrada Patrícia , Aaslyng Margit Dall
Published: October 2024

Protein increases satiety by, among other things, increasing the content of certain amino acids in the blood. Plant proteins generally have a lower digestibility than meat proteins. The digestibility increases after extrusion; thereby, extrusion potentially also increases the satiating effect. We investigated subjective appetite and ad libitum energy intake (adlib_EI) following ragú “bolognaise” meals with three different protein sources. We hypothesized that the satiating effect of texturized vegetable proteins (TVP) was comparable to that of animal protein (Meat) and that TVPs would have a stronger satiating effect than non-texturized legume proteins (Green). Test meals were theoretically designed to be similar in weight, energy (kJ), macronutrients and fiber. The in vitro protein digestibility (IVPD) and the amino acid composition were analyzed. A randomized, single-blinded, three-way, cross-over study including 25 healthy men was carried out. There were no significant differences between the three meals in terms of subjective appetite. The adlib_EI was significantly lower after the TVP meal (758 kJ) than after the Meat meal (957 kJ), with the Green meal in between (903 kJ). The IVPD was significantly higher in the Meat meal (30.72%) than in the Green meal (20.17%), with the TVP meal in between (21.05%). In conclusion, the TVP meal had a higher long-term satiating effect than a similar meal with meat.
Mannose and Lactobionic Acid in Nasal Vaccination: Enhancing Antigen Delivery via C-Type Lectin Receptors
Authors: Colaço Mariana , Cruz Maria T. , Almeida Luís Pereira de , Borges Olga
Published: October 2024

Background/Objectives: Nasal vaccines are a promising strategy for enhancing mucosal immune responses and preventing diseases at mucosal sites by stimulating the secretion of secretory IgA, which is crucial for early pathogen neutralization. However, designing effective nasal vaccines is challenging due to the complex immunological mechanisms in the nasal mucosa, which must balance protection and tolerance against constant exposure to inhaled pathogens. The nasal route also presents unique formulation and delivery hurdles, such as the mucous layer hindering antigen penetration and immune cell access. Methods: This review focuses on cutting-edge approaches to enhance nasal vaccine delivery, particularly those targeting C-type lectin receptors (CLRs) like the mannose receptor and macrophage galactose-type lectin (MGL) receptor. It elucidates the roles of these receptors in antigen recognition and uptake by antigen-presenting cells (APCs), providing insights into optimizing vaccine delivery. Results: While a comprehensive examination of targeted glycoconjugate vaccine development is outside the scope of this study, we provide key examples of glycan-based ligands, such as lactobionic acid and mannose, which can selectively target CLRs in the nasal mucosa. Conclusions: With the rise of new viral infections, this review aims to facilitate the design of innovative vaccines and equip researchers, clinicians, and vaccine developers with the knowledge to enhance immune defenses against respiratory pathogens, ultimately protecting public health.
An Assessment of Vegetation Changes in the Three-River Headwaters Region, China: Integrating NDVI and Its Spatial Heterogeneity
Authors: Mou Xuejie , Chai Huixia , Duan Cheng , Feng Yao , Wang Xiahui
Published: October 2024

Assessing vegetation changes in alpine arid and fragile ecosystems is imperative for informed ecological restoration initiatives and adaptive ecosystem management. Previous studies primarily employed the Normalized Difference Vegetation Index (NDVI) to reveal vegetation dynamics, ignoring the spatial heterogeneity alterations caused by bare soil. In this study, we used a comprehensive analysis of NDVI and its spatial heterogeneity to examine the vegetation changes across the Three-River Headwaters Region (TRHR) over the past two decades. A random forest model was used to elucidate the underlying causes of these changes. We found that between 2000 and 2022, 9.4% of the regions exhibited significant changes in both NDVI and its spatial heterogeneity. These regions were categorized into six distinct types of vegetation change: improving conditions (62.1%), regrowing conditions (11.0%), slight degradation (16.2%), medium degradation (8.4%), severe degradation (2.0%), and desertification (0.3%). In comparison with steppe regions, meadows showed a greater proportion of improved conditions and medium degradation, whereas steppes had more instances of regrowth and slight degradation. Climate variables are the dominant factors that caused vegetation changes, with contributions to NDVI and spatial heterogeneity reaching 68.9% and 73.2%, respectively. Temperature is the primary driver of vegetation dynamics across the different types of change, with a more pronounced impact in meadows. In severely degraded steppe and meadow regions, grazing intensity emerged as the predominant driver of NDVI change, with an importance value exceeding 0.50. Notably, as degradation progressed from slight to severe, the significance of this factor correspondingly increased. Our findings can provide effective information for guiding the implementation of ecological restoration projects and the sustainable management of alpine arid ecosystems.
Phosphogypsum with Rice Cultivation Driven Saline-Alkali Soil Remediation Alters the Microbial Community Structure
Authors: Lu Guanru , Feng Zhonghui , Xu Yang , Guan Fachun , Jin Yangyang , Zhang Guohui , Hu Jiafeng , Yu Tianhe , Wang Mingming , Liu Miao , Yang Haoyu , Li Weiqiang , Liang Zhengwei
Published: October 2024

The improvement of saline-alkali land plays a key role in ensuring food security and promoting agricultural development. Saline soils modifies the response of the soil microbial community, but research is still limited. The effects of applying phosphogypsum with rice cultivation (PRC) on soil physicochemical properties and bacterial community in soda saline-alkali paddy fields in Songnen Plain, China were studied. The results showed that the PRC significantly improved the physicochemical properties of soil, significantly reduced the salinity, increased the utilization efficiency of carbon, nitrogen, and phosphorus, and significantly increased the activities of urease and phosphatase. The activities of urease and phosphatase were significantly correlated with the contents of total organic carbon and total carbon. A redundancy analysis showed that pH, AP, ESP, HCO3−, and Na+ were dominant factors in determining the bacterial community structure. The results showed that PRC could improve soil quality and enhance the ecosystem functionality of soda saline-alkali paddy fields by increasing nutrient content, stimulating soil enzyme activity, and regulating bacterial community improvement. After many years of PRC, the soda-alkali soil paddy field still develops continuously and healthily, which will provide a new idea for sustainable land use management and agricultural development.
Magnesium Hydride Confers Osmotic Tolerance in Mung Bean Seedlings by Promoting Ascorbate–Glutathione Cycle
Authors: Zhang Yihua , Lu Xing , Yao Wenrong , Cheng Xiaoqing , Wang Qiao , Feng Yu , Shen Wenbiao
Published: October 2024

Despite substantial evidence suggesting that hydrogen gas (H2) can enhance osmotic tolerance in plants, the conventional supply method of hydrogen-rich water (HRW) poses challenges for large-scale agricultural applications. Recently, magnesium hydride (MgH2), a hydrogen storage material in industry, has been reported to yield beneficial effects in plants. This study aimed to investigate the effects and underlying mechanisms of MgH2 in plants under osmotic stress. Mung bean seedlings were cultured under control conditions or with 20% polyethylene glycol (PEG)-6000, with or without MgH2 addition (0.01 g L−1). Under our experimental conditions, the MgH2 solution maintained a higher H2 content and longer retention time than HRW. Importantly, PEG-stimulated endogenous H2 production was further triggered by MgH2 application. Further results revealed that MgH2 significantly alleviated the inhibition of seedling growth and reduced oxidative damage induced by osmotic stress. Pharmacological evidence suggests the MgH2-reestablished redox homeostasis was associated with activated antioxidant systems, particularly the ascorbate–glutathione cycle. The above observations were further supported by the enhanced activities and gene transcriptional levels of ascorbate peroxidase, monodehydroascorbate reductase, dehydroascorbate reductase, and glutathione reductase. Overall, this study demonstrates the importance of MgH2 in mitigating osmotic stress in mung bean seedlings, providing novel insights into the potential agricultural applications of hydrogen storage materials.
Micro-Nanoparticle Characterization: Establishing Underpinnings for Proper Identification and Nanotechnology-Enabled Remediation
Authors: Williams Wesley Allen , Aravamudhan Shyam
Published: October 2024

Microplastics (MPLs) and nanoplastics (NPLs) are smaller particles derived from larger plastic material, polymerization, or refuse. In context to environmental health, they are separated into the industrially-created “primary” category or the degradation derivative “secondary” category where the particles exhibit different physiochemical characteristics that attenuate their toxicities. However, some particle types are more well documented in terms of their fate in the environment and potential toxicological effects (secondary) versus their industrial fabrication and chemical characterization (primary). Fourier Transform Infrared Spectroscopy (FTIR/µ-FTIR), Raman/µ-Raman, Proton Nuclear Magnetic Resonance (H-NMR), Curie Point-Gas Chromatography-Mass Spectrometry (CP-gc-MS), Induced Coupled Plasma-Mass Spectrometry (ICP-MS), Nanoparticle Tracking Analysis (NTA), Field Flow Fractionation-Multiple Angle Light Scattering (FFF-MALS), Differential Scanning Calorimetry (DSC), Thermogravimetry (TGA), Differential Mobility Particle [Sizing] (DMPS), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), and Scanning Transmission X-ray Microspectroscopy (STXM) are reviewed as part of a suite of characterization methods for physiochemical ascertainment and distinguishment. In addition, Optical-Photothermal Infrared Microspectroscopy (O-PTIR), Z-Stack Confocal Microscopy, Mueller Matrix Polarimetry, and Digital Holography (DH) are touched upon as a suite of cutting-edge modes of characterization. Organizations, like the water treatment or waste management industry, and those in groups that bring awareness to this issue, which are in direct contact with the hydrosphere, can utilize these techniques in order to sense and remediate this plastic polymer pollution. The primary goal of this review paper is to highlight the extent of plastic pollution in the environment as well as introduce its effect on the biodiversity of the planet while underscoring current characterization techniques in this field of research. The secondary goal involves illustrating current and theoretical avenues in which future research needs to address and optimize MPL/NPL remediation, utilizing nanotechnology, before this sleeping giant of a problem awakens.
An Investigation of the Mechanical Properties of Flax/Basalt Epoxy Hybrid Composites from a Sustainability Perspective
Authors: Panico Martina , Cozzolino Ersilia , Papa Ilaria , Taha Iman , Lopresto Valentina
Published: October 2024

Currently, sustainability plays a central role in the response to global challenges, strongly influencing decisions in various sectors. From this perspective, global efforts to explore inventive and eco-friendly solutions to address the demands of industrialization and large-scale production are being made. Bio-based composites needed for lightweight applications benefit from the integration of natural fibers, due to their lower specific weight compared to synthetic fibers, contributing to the overall reduction in the weight of such structures without compromising the mechanical performance. Nevertheless, challenges arise when using natural fibers in composite laminates and hybridization seems to be a solution. However, there is still a lack of knowledge in the literature regarding the strategies and possibilities for reducing laminate thickness, without sacrificing the mechanical performance. This work aims to fill this knowledge gap by investigating the possibility of reducing the laminate thickness in hybrid flax/basalt composites made of plies, organized in the same stacking sequence, through only varying their number. Tensile, Charpy, flexural, and drop-weight tests were carried out for the mechanical characterization of the composites. The results obtained confirm the feasibility of achieving thinner hybrid composites, thus contributing to sustainability, while still having acceptable mechanical properties for structural applications.
Capitalizing on Religious Pluralism in U.S. Prison Ministry: Lessons from LSP Angola’s Inmate Seminary
Authors: Hallett Michael , Johnson Byron R.
Published: October 2024

The renewed growth of immersive “faith-unit” programs operating inside U.S. maximum-security prisons has brought with it a heightened emphasis on the practice of religion in correctional settings. Modeled from a prototype Christian seminary planted inside Louisiana State Penitentiary Angola, newer programs utilize outside religious educators for the credentialing of inmates into work assignments on behalf of prisons. As resource-challenged wardens deploy religiously credentialed inmates for leading new forms of prison ministry inside state facilities, research has not kept pace with the rapid growth of programs. Based on previous research, this article offers a retrospective account of the establishment of “offender ministries” at the Angola prison seminary planted at Louisiana State Penitentiary in 1994. While correctional leaders are obliged to accommodate the diverse religious identities of prisoners, private sponsors of immersive religious programs must balance doctrinal fealty with religious pluralism. Drawing from fieldnotes and on-site interviews in previous research, lessons from the history of Angola’s ecumenical prison seminary and “inmate ministry” programs are discussed while strengths and weaknesses are also highlighted.
Fast and Economic Microarray-Based Detection of Species-, Resistance-, and Virulence-Associated Genes in Clinical Strains of Vancomycin-Resistant Enterococci (VRE)
Authors: Osadare Ibukun Elizabeth , Monecke Stefan , Abdilahi Abdinasir , Müller Elke , Collatz Maximilian , Braun Sascha , Reissig Annett , Schneider-Brachert Wulf , Kieninger Bärbel , Eichner Anja , Rath Anca , Fritsch Jürgen , Gary Dominik , Frankenfeld Katrin , Wellhöfer Thomas , Ehricht Ralf
Published: October 2024

Today, there is a continuous worldwide battle against antimicrobial resistance (AMR) and that includes vancomycin-resistant enterococci (VRE). Methods that can adequately and quickly detect transmission chains in outbreaks are needed to trace and manage this problem fast and cost-effectively. In this study, DNA-microarray-based technology was developed for this purpose. It commenced with the bioinformatic design of specific oligonucleotide sequences to obtain amplification primers and hybridization probes. Microarrays were manufactured using these synthesized oligonucleotides. A highly parallel and stringent labeling and hybridization protocol was developed and employed using isolated genomic DNA from previously sequenced (referenced) clinical VRE strains for optimal sensitivity and specificity. Microarray results showed the detection of virulence, resistance, and species-specific genes in the VRE strains. Theoretical predictions of the microarray results were also derived from the sequences of the same VRE strain and were compared to array results while optimizing protocols until the microarray result and theoretical predictions were a match. The study concludes that DNA microarray technology can be used to quickly, accurately, and economically detect specifically and massively parallel target genes in enterococci.