bluuebunny/crossref_metadata_2025 huggingface dataset:
Why Did I Consult My Pharmacist about Herbal and Dietary Supplements? An Online Survey Amid the COVID-19 Pandemic in Malaysia
Authors: Wahab Mohd Shahezwan Abd , Jalani Muhammad Mustaqim , Goh Khang Wen , Ming Long Chiau , Faller Erwin Martinez
Published: September 2022

Herbal and dietary supplements (HDSs) are frequently obtained from community pharmacies, but community pharmacists (CPs) have been underutilized for information regarding them. This study aimed to determine the prevalence of, factors behind, and reasons for consultation with CPs among HDS consumers in Malaysia. A cross-sectional study using an online survey was conducted among conveniently sampled individuals in Malaysia. Reasons for consultation or non-consultation with CPs about HDSs were sought from the respondents. A logistic regression analysis was conducted to determine the predictors of consultation with CPs. Overall, 40.3% (239/593) of participants consulted CPs about the HDSs that they purchased. The participants were predominantly unmarried (362/588, 61.6%) and belonged to the 18–29 age group (332/593, 56%). The multivariate analysis showed that a suburban residential setting was the only significant predictor for consultation with CPs (adjusted odds ratio = 0.390, 95% CI = 0.260–0.583). Respondents who consulted CPs generally agreed that the CPs were the right people to consult on HDSs (mean = 4.37, SD = 0.73). However, their discussion with CPs regarding HDSs mostly revolved around the benefits and directions for use, but little on the potential risks. Meanwhile, most respondents who did not consult CPs agreed that they had never thought of consulting CPs about their HDS use (mean = 3.45, SD = 1.02). The majority of them referred to the Internet (61.3%, 217/354) and social media (59.9%, 212/354) for information about HDSs. The findings from this study show that more efforts are warranted in encouraging consumers to consult CPs about their HDS use and to enhance their awareness of the roles of CPs in ensuring the safe use of HDSs.
Service User and Carer Views and Expectations of Mental Health Nurses: A Systematic Review
Authors: Moyo Nompilo , Jones Martin , Kushemererwa Diana , Arefadib Noushin , Jones Adrian , Pantha Sandesh , Gray Richard
Published: September 2022

Service users’ views and expectations of mental health nurses in a UK context were previously reviewed in 2008. The aim of this systematic review is to extend previous research by reviewing international research and work published after the original review. Five databases were searched for studies of any design, published since 2008, that addressed service user and carer views and expectations of mental health nurses. Two reviewers independently completed title and abstract, full-text screening and data extraction. A narrative synthesis was undertaken. We included 49 studies. Most included studies (n = 39, 80%) were qualitative. The importance of the therapeutic relationship and service users being supported in their personal recovery by mental health nurses were core themes identified across included studies. Service users frequently expressed concern about the quality of the therapeutic relationship and indicated that nurses lacked time to spend with them. Carers reported that their concerns were not taken seriously and were often excluded from the care of their relatives. Our critical appraisal identified important sources of bias in included studies. The findings of our review are broadly consistent with previous reviews however the importance of adopting a recovery approach has emerged as a new focus.
Overview of the Role of Spatial Factors in Indoor SARS-CoV-2 Transmission: A Space-Based Framework for Assessing the Multi-Route Infection Risk
Authors: Zhen Qi , Zhang Anxiao , Huang Qiong , Li Jing , Du Yiming , Zhang Qi
Published: September 2022

The COVID-19 pandemic has lasted from 2019 to 2022, severely disrupting human health and daily life. The combined effects of spatial, environmental, and behavioral factors on indoor COVID-19 spread and their interactions are usually ignored. Especially, there is a lack of discussion on the role of spatial factors in reducing the risk of virus transmission in complex and diverse indoor environments. This paper endeavours to summarize the spatial factors and their effects involved in indoor virus transmission. The process of release, transport, and intake of SARS-CoV-2 was reviewed, and six transmission routes according to spatial distance and exposure way were classified. The triangular relationship between spatial, environmental and occupant behavioral parameters during virus transmission was discussed. The detailed effects of spatial parameters on droplet-based, surface-based and air-based transmission processes and virus viability were summarized. We found that spatial layout, public-facility design and openings have a significant indirect impact on the indoor virus distribution and transmission by affecting occupant behavior, indoor airflow field and virus stability. We proposed a space-based indoor multi-route infection risk assessment framework, in which the 3D building model containing detailed spatial information, occupant behavior model, virus-spread model and infection-risk calculation model are linked together. It is also applicable to other, similar, respiratory infectious diseases such as SARS, influenza, etc. This study contributes to developing building-level, infection-risk assessment models, which could help building practitioners make better decisions to improve the building’s epidemic-resistance performance.
Stress across the Lifespan: From Risk to Management—Conference Report on the Inaugural Canadian Stress Research Summit
Authors: Fiocco Alexandra J.
Published: September 2022

In 2021, the Toronto Metropolitan University Institute for Stress and Wellbeing Research welcomed over 200 conference delegates across Canada to the inaugural Canadian Stress Research Summit (CSRS) to share ideas and foster collaboration among Canadian scholars. This conference was unique from existing international stress-related conferences as it bridged science and community. The objective of this conference report is to provide an overview of the 3-day virtual inaugural stress conference, offering a summary of the keynote addresses, themed symposia, spotlight presentations, graphical designs of selected presentations, and conference feedback. Overall, the CSRS highlighted important methodological considerations in understanding the relationship between stress exposure and various outcomes of interest that pertain to the mental health and wellbeing of Canadians. Furthermore, there is a need for continued work to understand stress across the lifespan from an inclusive and diverse Canadian lens.
Clinical and Aesthetic Outcomes of Multiple Gingival Recessions Coverage with Modified Coronally Advanced Tunnel and Subepithelial Connective Tissue Graft in Maxilla and Mandible: A 2-Year Retrospective Study
Authors: Skierska Izabela , Wyrębek Beata , Górski Bartłomiej
Published: September 2022

Limited long-term data are available when analyzing gingival recession coverage between the maxillary and mandibular sites. Therefore, the aim of this study was to evaluate the influence of location (maxilla versus mandible) of multiple gingival recessions on 24 months clinical and aesthetic outcomes of modified coronally advanced tunnel with subepithelial connective tissue graft. Forty patients with multiple gingival recessions (GR) located at maxillary or mandibular teeth were treated between January 2018 and December 2019. Reduction in GR, average root coverage (ARC), complete root coverage (CRC), increase in keratinized tissue width (KTW), increase in gingival thickness (GT), and aesthetic evaluation with the root coverage esthetic score (RES) were evaluated after 24 months. Thirty patients with 270 recessions in the upper teeth and ten patients with 90 recessions in the lower teeth completed the 2-year recall. The differences between preoperative and postoperative clinical parameters showed statistical significance only within but not between groups. ARC at 2 years was 93.31% for maxillary teeth and 93.06% for mandibular teeth (p = 0.7906). Mean RES values were comparable for upper and lower teeth (9.25 versus 8.92, respectively, p = 0.6733). However, upper teeth achieved significantly higher scores for marginal tissue contour (MTC), muco-gingival junction alignment (MGJ), and gingival color (GC). Lower teeth had decreased chances of receiving better RES (OR = 0.49, CI 0.24–0.99, p = 0.0457) in regression analysis, when compared with upper teeth. MCAT + SCTG achieved comparably favorable 2-year outcomes for the treatment of multiple GR in upper and in lower teeth. However, the individual RES components were higher in maxillary teeth, and upper teeth had higher odds of receiving better RES.
Subclinical Hearing Deficits in Noise-Exposed Firefighters
Authors: Snapp Hillary A. , Schaefer Solle Natasha , Millet Barbara , Rajguru Suhrud M.
Published: September 2022

Noise-induced hearing loss (NIHL) is the most prevalent occupational disease in the world and firefighters are at increased risk of NIHL due to their frequent exposure to hazardous levels of noise during service. Adverse effects of NIHL include acceleration of age-related hearing loss and an increased risk of cognitive decline. A critical challenge in addressing NIHL is the delayed clinical presentation of symptoms and lack of sensitive tools for early detection. To study the early clinical symptoms of NIHL in this high-risk group, we collected hearing function data including behavioral audiometric thresholds and distortion product otoacoustic emissions (DPOAEs) in 176 firefighters during annual physical assessments. Results revealed significant deficits in cochlear outer hair cell function in the presence of normal audiograms. Additionally, 55% of firefighters self-reported changes in hearing, while 20% self-reported concerns about their balance. This study is the first to characterize DPOAEs in firefighters who display decreased DPOAE amplitudes with increasing years in the fire service. These effects were observed even when controlling for hearing loss and age and are suggestive of a link between hearing loss and occupational exposure to hazardous noise.
Intention for Warm-Up among Children and Adolescents Scale: Development and Initial Validation
Authors: Ding Liyi , Van Raalte Judy L. , Mackey Marcia , Brewer Britton W. , Jin Min , Chu Minming , Weng Lijun
Published: September 2022

The purpose of this study was to develop and validate the Intention for Warm-up among Children and Adolescents Scale (IWCAS). There were four phases and four sets of participants in the development of the IWCAS. In the first phase, the domains of intention were defined, and related components were developed, organized, and validated. In the second phase, 446 elementary and middle school students participated in a pilot study for the first version of the scale, which was revised based on the information obtained. In the third phase, 12 graduates in sports pedagogy served on an expert panel and organized the items into domain areas and developed a second version of the IWCAS. In the final phase, 1322 elementary and middle school students from three k-12 schools completed the revised version of the IWCAS, and exploratory and confirmatory factor analyses were conducted. Based on the results, the IWCAS was shortened by deleting some items in two domains; this resulted in 11 items of the final version with 3 domains: (1) attitude toward warm-up, (2) subjective norm, and (3) perceived behavioral control that, according to the indices, generate reliable and structurally valid scores. The composite internal consistency for the three domains ranged from 0.74 to 0.85. The researchers hypothesized the IWCAS is a valid and reliable scale, which can be used by P.E. teachers or coaches to evaluate the intention of primary and secondary school students to perform warm-ups.
Post-Traumatic Stress Disorder after the 6.1 Magnitude Earthquake in Piura, Peru: A Cross-Sectional Study
Authors: Valladares-Garrido Mario J. , Zapata-Castro Luis E. , Peralta C. Ichiro , García-Vicente Abigaíl , Astudillo-Rueda David , León-Figueroa Darwin A. , Díaz-Vélez Cristian
Published: September 2022

In Peru, major disasters like the 2007 Pisco earthquake have produced high rates of post-traumatic stress. However, evidence is still needed to strengthen interventions. In 2021, a major earthquake struck Piura, in northern Peru. In this context, we aimed to assess the prevalence of PTSD and its associated factors. A cross-sectional study was conducted during August–September 2021 in people who experienced the 6.1 Piura earthquake on 30 July 2021. The questionnaire included the PCL-C, CD-RISC, ISI, HFIAS, and additional demographic data. Generalized linear models were used. The prevalence of PTSD was 20.3%. Household income was between PEN 2001 and 3000 (PR = 4.26, 95% CI: 1.08–16.75), smoking (PR = 2.49, 95% CI: 1.03–6.01), experience of a nervous breakdown (PR = 1.83, 95% CI: 1.09–3.09), moderate food insecurity (PR = 2.91, 95% CI: 1.10–7.73), and severe insomnia (PR = 8.25, 95% CI: 2.22–30.71) increased the prevalence of PTSD. One out of five individuals experienced post-traumatic stress symptoms after the 2021 earthquake in Piura, which varies depending on socioeconomic, psychosocial, and individual factors. Further research should strengthen these findings to ensure a fair and early mental health intervention against new seismic events in this and other Peruvian regions.
Comprehensive Time-Course Effects of Combined Training on Hypertensive Older Adults: A Randomized Control Trial
Authors: Sardeli Amanda V. , Gáspari Arthur F. , dos Santos Wellington M. , de Araujo Amanda A. , de Angelis Kátia , Mariano Lilian O. , Cavaglieri Cláudia R. , Fernhall Bo , Chacon-Mikahil Mara Patrícia T.
Published: September 2022

The aim was to identify whether 16 weeks of combined training (Training) reduces blood pressure of hypertensive older adults and what the key fitness, hemodynamic, autonomic, inflammatory, oxidative, glucose and/or lipid mediators of this intervention would be. Fifty-two individuals were randomized to either 16 weeks of Training or control group who remained physically inactive (Control). Training included walking/running at 63% of V˙O2max, three times per week, and strength training, consisting of one set of fifteen repetitions (seven exercises) at moderate intensity, twice per week. Both groups underwent a comprehensive health assessment at baseline (W0) and every four weeks, for 16 weeks total. p-value ≤ 0.05 was set as significant. Training did not reduce blood pressure. It increased V˙O2max after eight weeks and again after 16 weeks (~18%), differently from the Control group. At 16 weeks, Training increased strength (~8%), slightly reduced body mass (~1%), and reduced the number of individuals with metabolic syndrome (~7%). No other changes were observed (heart rate, carotid compliance, body composition, glycemic and lipid profile, inflammatory markers and oxidative profile, vasoactive substances, heart rate variability indices). Although Training increased cardiorespiratory fitness and strength, Training was able to reduce neither blood pressure nor a wide range of mediators in hypertensive older adults, suggesting other exercise interventions might be necessary to improve overall health in this population. The novelty of this study was the time-course characterization of Training effects, surprisingly demonstrating stability among a comprehensive number of health outcomes in hypertensive older adults, including blood pressure.
Change in Factors Affecting Cyberbullying of Korean Elementary School Students during the COVID-19 Pandemic
Authors: Choi Yeon-Jun , Shin So Young , Lee Julak
Published: September 2022

The importance of social networking and the online environment as core factors in building relationships has grown as a result of the COVID-19 pandemic, which limited in-person activities. As classes transitioned to online platforms, there was an influx of elementary school students into the cyberspace, increasing the risk of exposure to cyberbullying. This study analyzed the factors influencing the experience of cyberbullying among Korean elementary school students around 2020, when the spread of COVID-19 began in earnest, and thus suggests directions for cyberbullying prevention measures for the post-COVID-19 era. This comparative study used binary logistic regression to analyze data from the “Cyber Violence Survey” conducted by the Korea Communications Commission in 2019 and 2020. The analysis confirmed that interactions between parents and children, cyberbullying control by schools, and recognition of cyberbullying as a problem had statistically significant influences on cyberbullying experience only in 2020 (i.e., when the pandemic began). Overall, this study emphasizes the importance of raising awareness about cyberbullying among elementary school students and taking preventive action through a home-school system to address cyberbullying in the post-COVID-19 era.
Factors Associated with Antiretroviral Therapy Toxicity Out-Comes in Patients with and without Hypertension
Authors: Dlamini Sabelo Bonginkosi , Wu Ming-Tsang , Dahms Hans-Uwe
Published: September 2022

Background: Negative effects of antiretroviral therapy (ART) drugs on HIV/AIDS patients are one of the major health issues in the therapeutic treatment of this communicable disease. This holds particularly for people living with HIV (PLHIV) who might have a non-communicable disease (like hypertension), which also requires a lifetime treatment. In this study, we investigated the association between hypertension and other possible factors on ART toxicity markers in patients with hypertension, compared to those without hypertension. Methods: This retrospective longitudinal study reviewed chronic patient files of 525 patients (of which 222 were hypertensive) who satisfied the inclusion criteria and were on ART at a hospital in central Eswatini. Specific levels of estimated glomerular filtration (eGFR), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were used as drug toxicity markers. To analyze the longitudinal data between the exposure of interest and outcome variables, a Generalized Estimated Equation method was employed. Results: Participants with hypertension had decreased eGFR compared to those without hypertension (β = −2.22; p-value = 0.03). There was no significant association between ALT, AST and hypertension (p-value = 0.34 and 0.20, respectively). Factors that were found to have a significant association with ART toxicity markers included age, sex, ART duration, hypertension treatment and time of study. The eGFR was found to be significantly increasing over the study period (p-value < 0.001) for all participants. The significance was consistent in both hypertensive and non-hypertensive participants independently (p-value = 0.002 and <0.001, respectively). The overall trends of ALT and AST over time were also significant (p-value = 0.003 and <0.001, respectively). Conclusions: Patients with hypertension had decreased eGFR, and there was a significant association of eGFR with time of the study. Special attention, therefore, to monitor calamities which are indicated by a decrease of eGFR (like renal impairment) should be given in PLHIV on ART with hypertension, especially more so if they were on ART for longer time.
Knowledge and Perceptions about Cervical Cancer and HPV Screening in Women in Rural Areas of Ecuador: A Qualitative Research Study
Authors: Bautista-Valarezo Estefanía , Vega Crespo Bernardo , Maldonado-Rengel Ruth , Espinosa María , Neira Vivian , Verhoeven Veronique
Published: September 2022

Background: Cervical cancer continues to be a major health problem in developing countries. Educational programs, as well as Pap and HPV screening and vaccination, are important tools to reduce the morbidity and mortality rates associated with this disease. The objective of this study is to explore the diverse knowledge and perceptions about cervical cancer and the different diagnostic tests for HPV of populations living in the rural parish “El Valle”. Method: A qualitative study was conducted through eight focus groups, which included 46 participants from mixed ethnic groups. A phenomenological analysis was performed. Results: Four topics and seven sub-topics were identified. By analyzing all the narratives, it was possible to identify that the perception of cervical cancer was focused on its severity, secondary to its infectious process and screening periodicity. However, despite the diverse knowledge, indigenous people do not relate it to the human papilloma virus; in addition, there is also certain resistance to undergo the Pap smear test, for reasons such as inaccessibility and its sampling process. Conclusions: It is necessary to develop educational programs for the prevention of cervical cancer and to implement diagnostic alternatives to reach populations with precarious accessibility, as well as women who refuse to undergo the Pap smear test.
Are You Willing to Protect the Health of Older People? Intergenerational Contact and Ageism as Predictors of Attitudes toward the COVID-19 Vaccination Passport
Authors: Visintin Emilio Paolo , Tasso Alessandra
Published: September 2022

Since the beginning of the COVID-19 pandemic, the vulnerability of older people to COVID-19 has been stressed in political discourse and the mass media, with the call to protect older adults. Therefore, policies aimed at reducing the spread of coronavirus, such as the COVID-19 vaccination passport policy, might be perceived as policies aimed at preserving the health of older people, and negative attitudes toward older people (i.e., ageism) might underlie negative attitudes toward such policies. While intergenerational contact is one of the main antecedents of reduced ageism, the pandemic has forced people to separate, and direct intergenerational contact in particular might have been reduced, possibly being replaced by telephone and virtual contact. In a correlational study (N = 153 Italian university students) we found that quantity and quality of direct intergenerational contact diminished during the pandemic. Virtual intergenerational contact was unexpectedly less frequent than direct contact. Quality of direct contact before the pandemic was associated, over and above the effects of other contact forms under investigation, with reduced ageism, which was in turn associated with negative attitude toward the vaccination passport. Findings will be discussed focusing on the roles of intergenerational contact and ageism for public health.
Evolution of Medical Students’ Perception of the Patient’s Right to Privacy
Authors: Terán Alberto Álvarez , Palazuelos Camilo , Dierssen-Sotos Trinidad , Alonso-Molero Jessica , Llorca Javier , Gómez-Acebo Inés
Published: September 2022

During clinical rotations, medical students experience situations in which the patients’ right to privacy may be violated. The aim of this study is to analyze medical students’ perception of clinical situations that affect patients’ right to privacy, and to look for the influential factors that may contribute to the infringement on their rights, such as the students’ age, sex, academic year or parents’ educational level. A cross-sectional study was conducted with a survey via “Google Drive”. It consisted of 16 questions about personal information, 24 questions about their experience when rotating and 21 questions about their opinion concerning several situations related to the right to privacy. A total of 129 medical students from various Spanish medical schools participated. Only 31% of 3rd–6th year students declared having signed a confidentiality agreement when starting their clinical practice, and most students (52%) reported that doctors “sometimes”, “rarely” or “never” introduce themselves and the students when entering the patients’ rooms. Additionally, about 50% of all students reported that they would take a picture of a patient’s hospitalization report without his/her (consent), which would be useful for an assignment. Important mistakes during medical students’ rotations have been observed, as well as a general lack of knowledge regarding patient’s right to privacy among Spanish medical students. Men and older students showed better knowledge of current legislation, as well as those whose parents were both university-educated and those in higher academic years.
Neuroticism and Aggressive Behavior among Left-Behind Children: The Mediating Roles of Interpersonal Sensitivity and Bullying Victimization
Authors: Dong Yinghan , Liu Fangfang , Jiang Yingjie , Wei Siyuan
Published: September 2022

When children are “left behind”, aggressive behavior is a common manifestation of problem behaviors, and several previous studies suggested that neuroticism has characteristics such as oversensitivity and impulsivity, which may be important predictors of aggressive behavior. However, the mediating mechanisms underlying this relationship are unknown. This study is designed to analyze how neuroticism leads to left-behind children’s aggressive behaviors through mediators of interpersonal sensitivity and bullying victimization. A sample of 1478 Chinese children (67.72% left-behind children; 37.28% non-left-behind children) through whole-class contact and voluntary participation completed measurements of neuroticism, interpersonal sensitivity, bullying victimization, and aggressive behavior. Findings from the mediation analysis show that interpersonal sensitivity and bullying victimization could mediate the relationship between neuroticism and aggressive behavior among left-behind children separately and sequentially. These findings suggest helpful ways to reduce the aggressive behaviors of left-behind children by decreasing interpersonal sensitivity and bullying victimization.
Effect of Pelvic Floor Workout on Pelvic Floor Muscle Function Recovery of Postpartum Women: Protocol for a Randomized Controlled Trial
Authors: Zhu Hongmei , Zhang Di , Gao Lei , Liu Huixin , Di Yonghui , Xie Bing , Jiao Wei , Sun Xiuli
Published: September 2022

Background: There is a risk of pelvic floor dysfunction (PFD) from baby delivery. Many clinical guidelines recommend pelvic floor muscle training (PFMT) as the conservative treatment for PFD because pelvic floor muscles (PFMs) play a crucial role in development of PFD. However, there is disagreement about the method and intensity of PFM training and the relevant measurements. To pilot the study in PFM training, we designed a Pelvic Floor Workout (PEFLOW) for women to train their pelvic through entire body exercises, and we planned a trial to evaluate its effectiveness through comparing the outcomes from a group of postpartum women who perform PELFLOW at home under professional guidance online with the control group. Methods/design: The randomized controlled trial was projected to be conducted from November 2021 to March 2023. A total of 260 postpartum women would be recruited from the obstetrics departments of the study hospital and women would be eligible for participation randomized into experimental or control groups (EG/CG) if their PFM strength are scaled by less than Modified Oxford grading Scale (MOS) to be less than grade 3. Women in EG would perform a 12-week PEFLOW online under the supervision and guidance of a physiotherapist, while women in CG would have no interventions. Assessments would be conducted at enrollment, post intervention (for EG) or 18th to 24th week postpartum (for CG), and 1 year postpartum. Assessment would be performed in terms of pelvic floor symptoms, including MOS, cough stress test, urinary leakage symptoms, pelvic organ prolapse quantitation (POP-Q), and vaginal relaxation, clinic examinations including Pelvic floor electrophysiological test, Pelvic floor ultrasound and Spine X-ray, overall body test including trunk endurance test, handgrip test, body composition test, and questionnaires including International Physical Activity Questionnaire Score-Short Form(IPAQ-SF), Pelvic Floor Distress Inventory Questionnaire-20 (PFDI-20), Pelvic Floor Impact Questionnaire-7 (PFIQ-7), the 6-item Female Sexual Function Index (FSFI-6), and the Pittsburgh Sleep Quality Index (PSQI). Primary analysis will be performed to test our main hypothesis that PEFLOW is effective with respect to strengthen PFM strength. Discussion: This trial will demonstrate that pelvic floor-care is accessible to most women and clinical practice on PFD may change relevantly should this study find that Online PEFLOW approach is effective to improve PFMs. Trial registration: ClinicalTrials.gov, NCT05218239.
Peaking Global and G20 Countries’ CO2 Emissions under the Shared Socio-Economic Pathways
Authors: Kong Yuan , Feng Chao , Guo Liyang
Published: September 2022

Mitigating climate change requires long-term global efforts. The aim of this study is to simulate the possible paths of CO2 emissions in G20 countries and the world from 2020 to 2050, by using the STIRPAT model and SSP scenarios with different constraints (SSP baseline, SSP-3.4). The results show that: (1) the world’s CO2 emissions cannot peak in the SSP baseline scenarios, but can peak in the SSP-3.4 scenarios through four paths other than the high fossil energy consumption path; (2) for G20 countries, in the SSP baseline scenarios, 13 countries such as China, the United States, and the United Kingdom can achieve the peak, while six countries such as Argentina, India, and Saudi Arabia cannot. In the SSP-3.4 scenarios, Saudi Arabia cannot achieve the peak, while other countries can achieve the peak, and most of them are likely to achieve significant CO2 emission reductions by 2050; (3) climate goals have a crowding-out effect on other sustainable development goals, with less impact on developed countries and a greater impact on developing countries; and (4) the optimization of the energy structure and a low energy intensity can greatly advance the peak time of CO2 emissions.
Public Health Services, Health Human Capital, and Relative Poverty of Rural Families
Authors: Yang Yingya , Zhou Liangliang , Zhang Chongmei , Luo Xin , Luo Yihan , Wang Wei
Published: September 2022

With the successful completion of the battle against poverty, after 2020, the focus and difficulty of China’s poverty governance will change from solving absolute poverty to alleviating relative poverty. Analyzing and studying the alleviation of relative poverty from the perspective of public health services is in line with the current needs of consolidating and expanding poverty alleviation in China, and it is also of great significance to building a long-term solution mechanism for relative poverty. In this study, basic panel data were constructed by using the data of five CFPS surveys in 2010, 2012, 2014, 2016, and 2018 and matched with the macro data. The correlation between public health services and rural households’ relative poverty was also analyzed by using logit regression analysis and the KHB mediation effect decomposition method. The results show that (1) public health services play a significant role in promoting the accumulation of health human capital, improving individual feasible ability, and alleviating the relative poverty of rural families; (2) the improvement of public health services is conducive to the alleviation of the relative poverty of rural families; (3) we should continue to increase investment in public health care in underdeveloped areas and strive to promote the balanced development of public health services, so as to further consolidate and expand the achievements of poverty eradication.
Post-Acute COVID-19 Sequelae in a Working Population at One Year Follow-Up: A Wide Range of Impacts from an Italian Sample
Authors: Buonsenso Danilo , Gualano Maria Rosaria , Rossi Maria Francesca , Valz Gris Angelica , Sisti Leuconoe Grazia , Borrelli Ivan , Santoro Paolo Emilio , Tumminello Antonio , Gentili Carolina , Malorni Walter , Valentini Piero , Ricciardi Walter , Moscato Umberto
Published: September 2022

Long COVID-19 is a term used to describe the symptomatic sequelae that develop after suffering from COVID-19. Very few studies have investigated the impact of COVID-19 sequelae on employment status. The aim of this research was to characterise sequelae of COVID-19 in a population of workers who tested positive for COVID-19, with a follow-up within one year of the acute illness, and to analyse the possible association between this and changes in the workers’ occupational status. In this retrospective cohort study, a questionnaire was administered to 155 workers; descriptive, univariate (chi-square tests), and multivariate (logistic regression model) analyses were carried out. The mean age was 46.48 years (SD ± 7.302); 76 participants were males (49.7%), and 33 participants reported being current smokers (21.3%). Overall, 19.0% of patients reported not feeling fully recovered at follow-up, and 13.7% reported a change in their job status after COVID-19. A change in occupational status was associated with being a smoker (OR 4.106, CI [1.406–11.990], p = 0.010); hospital stay was associated with age > 46 years in a statistically significant way (p = 0.025) and with not feeling fully recovered at follow-up (p = 0.003). A persistent worsening in anxiety was more common in women (p = 0.028). This study identifies smoking as a risk factor for workers not able to resume their job; furthermore, occupational physicians should monitor mental health more closely after COVID-19, particularly in female workers.
Risk Factors Associated with Passengers with Imported Dengue Fever at International Airports in Taiwan
Authors: Wang Ying-Yun , Tsay Pei-Kwei
Published: September 2022

Dengue fever (DF) is a mosquito-borne disease prevalent in the tropics (e.g., sub-Saharan Africa, Asia, and Central and South America) and a common cause of febrile illness in travelers. The high incidence of imported DF in Taiwan has led to a domestic outbreak. This study explored the risk factors associated with individuals given diagnoses of imported DF at international airports in Taiwan. The results may serve as a reference for DF prevention. In this retrospective study, data from the symptom notification system database of the Taiwan Centers for Disease Control (TCDC) were used. These data concerned travelers who returned to Taiwan from DF-endemic areas with suspected DF symptoms. The epidemiological characteristics of the cases were analyzed, and 28 variables related to DF infection were included in the multivariate logistic regression analysis. In 2018–2019, there were 8656 cases (451 positive and 8205 negative cases). The results revealed DF symptoms and a 16–30-day stay in endemic areas to be independent risk factors and the presence of three respiratory symptoms and <10 days of short-term travel to be protective factors. These results may enable the accurate assessment of symptoms in travelers with DF as well as the risk factors associated with imported DF, lowering the risk of indigenous DF outbreaks caused by imported DF.
The Impact of Payment Scheme Changes on Medication Adherence and Persistence of Patients Diagnosed with Depression in Korea
Authors: Shin Gyeongseon , Jang Bohwa , Bae Green , Jeon Ha-Lim , Bae SeungJin
Published: September 2022

As of 1 July 2018, the Korean National Health Insurance Service (NHIS) changed the fee schedule for individual psychotherapy (IP). We sought to analyze the impact of the IP payment scheme changes on the medication adherence and persistence of patients diagnosed with depression in Korea. We utilized the NHIS claims database from 2017 to 2019. Patients who were newly diagnosed with depression and utilized IP and were prescribed antidepressants during the study period were included. Adherence was measured using the medication possession ratio (MPR), and persistence was measured using the length of therapy (LOT) during the follow-up period. Adherence and persistence during the pre-policy period (before the change of the payment scheme, from January 2018 until June 2018) and the post-policy period (after the change, from July 2018 until December 2019) were compared. During the study period, a total of 176,740 patients with depression were identified. The average MPR significantly increased from 0.20 to 0.33 in the pre- and post-policy periods, respectively (p < 0.001). The average LOT of the patients improved considerably from 36 to 56 days in the pre- and post-policy periods, respectively (p < 0.001). Poisson regression analysis showed that patients with depression who were female, 19–34 years of age (vs. 50–64 years or over 64 years), and in the post-policy period were significantly associated with greater adherence and persistence rates. Payment scheme changes were associated with an increased adherence and persistence of medication use among patients diagnosed with depression.
Association between Maternal Anxiety and Children’s Problem Behaviors: A Systematic Review and Meta-Analysis
Authors: Song Zhanmei , Huang Jie , Qiao Tianqi , Yan Jingfeng , Zhang Xueying , Lu Dengcheng
Published: September 2022

Although numerous studies have found that maternal anxiety is a risk factor for the development of children’s problem behaviors, and there is a possible role of genes in the association between the two. And anxious mothers caring for their children can also affect the development of children’s problem behaviors. However, there is also considerable evidence from studies that refute this view. This study used a meta-analysis to explore the relationship between maternal anxiety and preschool children’s problem behaviors. Through literature retrieval and selection, in terms of the criteria for inclusion in the meta-analysis, 88 independent effect sizes (34 studies, 295,032 participants) were picked out as meta-analysis units. The test for heterogeneity illustrated that there was significant heterogeneity in 88 independent effect sizes, while the random effects model was an appropriate model for the subsequent meta-analysis. The publication bias test indicated that the impact of publication bias was modest but the major findings remained valid. In addition, in terms of the tentative review analysis and research hypotheses, the random effects model was used as a meta-analysis model. The research revealed that maternal anxiety was significantly positively correlated with preschool children’s internalizing problem behaviors, externalizing problem behaviors, and overall problem behaviors. The moderating effect analysis showed that region and gender of the child affected the relationship between maternal anxiety and children’s internalizing problem behaviors and externalizing problem behaviors, and region, child’s age and gender, mother’s age, and education level affected maternal anxiety and preschool children’s problems behavioral relationship. Hence, these results affirmed the role of maternal anxiety and emphasized the need to pay attention to the demographic characteristics and cultural background of the subjects during the research process and consider the generalizability of the conclusions under different circumstances.
Development and Psychometric Assessment of a Questionnaire for the Detection of Invisible Violence against Women
Authors: Dobarrio-Sanz Iria , Fernández-Vargas Anabel , Fernández-Férez Alba , Vanegas-Coveña Diana Patricia , Cordero-Ahiman Otilia Vanessa , Granero-Molina José , Fernández-Sola Cayetano , Hernández-Padilla José Manuel
Published: September 2022

Background. Invisible violence against women (IVAW) can be understood as the set of attitudes, behaviors, and subtle beliefs that men use to subordinate women and that are culturally accepted. These behaviors can be a risk factor for intimate partner violence (IPV), so it is important to design tools that allow us to detect it early. The aim of this study was to design and psychometrically assess a questionnaire for the detection of invisible violence against women (Q-IVAW). Methodology. A descriptive cross-sectional methodological study carried out in three phases: (1) development of the initial version; (2) pilot study (N = 51); and (3) final validation study (N = 990). The tool’s reliability, validity, and legibility were assessed. To assess reliability, the internal consistency (Cronbach’s α) was analyzed. The validity assessment included an analysis of content, criterion, and construct validity. Results. The EFA revealed that the Q-IVAW was comprised of five factors that explained 55.85% of the total variance found. The Q-IVAW showed very high reliability (α = 0.937), excellent content validity, and good construct validity. The criterion validity analysis showed a moderate correlation between A-IPVAW and Q-IVAW (r = 0.30; p < 0.001). Conclusion. The psychometric assessment of the Q-IVAW yielded good results, which could support the tool’s ability to assess how often women are subjected to inviable violent behaviors by their partners.
Pharmaceuticals and Personal Care Products across Different Water Bodies in Taihu Lake Basin, China: Occurrence, Source, and Flux
Authors: Huang Jichao , Ding Jiannan , Jiang Hang , Wang Zhenguo , Zheng Lixing , Song Xiaojun , Zou Hua
Published: September 2022

Although pharmaceuticals and personal care products (PPCPs) have attracted great attentions, their occurrence characteristics across different water bodies at a basin scale remain poorly understood. To grasp a more comprehensive understanding of PPCP pollution from the perspective of the whole basin, the occurrence, spatial and seasonal variation, source, and flux of thirteen PPCPs across the different environmental compartments of the northern Taihu Lake Basin (TLB) were studied. The results showed that the non-therapeutic pharmaceuticals caffeine (CFI) and n, n-diethyl-m-toluamide (DEET) were the main components across the different environmental compartments. The total concentrations of detected PPCPs ranged from 0.2 to 2437.9 ng/L. Higher concentrations of PPCPs were observed in spring and autumn, which were mainly attributed to seasonal differences in PPCP consumption. Generally, pollution level was higher in industry and agriculture area and in the inner bay and southwest of Taihu Lake. Source apportionment indicated that untreated water was the main source of PPCPs in river waters of the northern TLB. Flux estimation showed that the mean annual flux of PPCPs from northern TLB to Taihu Lake in 2021 was 1.6 t/a, which was higher in comparison with other areas. Overall, the resulting data will be useful to enrich the research of PPCPs in freshwater for environmental investigations.
Stabilization of Recycled Concrete Aggregate Using High Calcium Fly Ash Geopolymer as Pavement Base Material
Authors: Tiyasangthong Sermsak , Yoosuk Piyathida , Krosoongnern Kitsada , Sakdinakorn Ratchanon , Tabyang Wisitsak , Phojan Worawit , Suksiripattanapong Cherdsak
Published: September 2022

This research investigated high calcium fly ash geopolymer stabilized recycled concrete aggregate (RCA-FAG) as pavement base material. The effect of recycled concrete aggregate (RCA):high calcium fly ash (FA) ratios, sodium silicate (Na2SiO3):sodium hydroxide (NaOH) ratio, and curing time on the unconfined compressive strength (UCS) and scanning electron microscope (SEM) properties of RCA-FAG samples were evaluated. The maximum dry unit weight of the RCA-FAG sample was 20.73 kN/m3 at RCA:FA ratio of 80:20 and Na2SiO3:NaOH ratio of 60:40. The 7-d UCS of RCA-FAG samples increased as the FA content and Na2SiO3:NaOH ratio increased. The 7-d UCS of the RCA-FAG sample was better than that of the RCA with no FA because FA particles filled in RCA particles, resulting in a dense matrix. The 7-d UCS of RCA-FAG samples passed the 7-d UCS requirement for the low-traffic road. All ingredients met the 7-d UCS requirement for the high-traffic road except the sample with RCA:FA of 100:0 and Na2SiO3:NaOH of 50:50 and 60:40. The 7-d SEM images indicated that spherical FA and RCA particles are bonded together, resulting in the dense matrix for all Na2SiO3:NaOH ratios. The proposed equation for predicting the UCS of RCA-FAG offered a good coefficient of correlation, which is useful in designing pavement base material from RCA-FAG material.
Crystallographic and Theoretical Study of Osme Bonds in Nitrido-Osmium(VI) Complexes
Authors: Gomila Rosa M. , Frontera Antonio
Published: September 2022

Osme bonds have been recently defined as the attractive interaction between an element of group 8 acting as an electrophile and any atom or group of atoms acting as a nucleophile. To date, the known examples of osme bonds in X-ray structures involve mostly the highly reactive OsO4 and amines and amine oxides. In this work, evidence supporting the existence of osme bonds in osmium(VI) derivatives is reported. In particular, nitrido-osmium(VI) complexes that present square-pyramidal geometries are well disposed to participate in osme bonds opposite to the Os≡N bond. By using a combination of experimental and theoretical results, the existence and importance of this new class of σ-hole interactions is demonstrated in the solid state of several nitrido-osmium(VI) derivatives.
Analysis of Polyadenylation Signal Usage with Full-Length Transcriptome in Spodoptera frugiperda (Lepidoptera: Noctuidae)
Authors: Fang Liying , Guo Lina , Zhang Min , Li Xianchun , Deng Zhongyuan
Published: September 2022

During the messenger RNA (mRNA) maturation process, RNA polyadenylation is a key step, and is coupled to the termination of transcription. Various cis-acting elements near the cleavage site and their binding factors would affect the process of polyadenylation, and AAUAAA, a highly conserved hexamer, was the most important polyadenylation signal (PAS). PAS usage is one of the critical modification determinants targeted at mRNA post-transcription. The full-length transcriptome has recently generated a massive amount of sequencing data, revealing poly(A) variation and alternative polyadenylation (APA) in Spodoptera frugiperda. We identified 50,616 polyadenylation signals in Spodoptera frugiperda via analysis of full-length transcriptome combined with expression Sequence Tags Technology (EST). The polyadenylation signal usage in Spodoptera frugiperda is conserved, and it is similar to that of flies and other animals. AAUAAA and AUUAAA are the most highly conserved polyadenylation signals of all polyadenylation signals we identified. Additionally, we found the U/GU-rich downstream sequence element (DSE) in the cleavage site. These results demonstrate that APA in Spodoptera frugiperda plays a significant role in root growth and development. This is the first polyadenylation signal usage analysis in agricultural pests, which can deepen our understanding of Spodoptera frugiperda and provide a theoretical basis for pest control.
Predicting the Weathering Time by the Empty Puparium of Sarcophaga peregrina (Diptera: Sarcophagidae) with the ANN Models
Authors: Zhang Xiangyan , Bai Yang , Ngando Fernand Jocelin , Qu Hongke , Shang Yanjie , Ren Lipin , Guo Yadong
Published: September 2022

Empty puparium are frequently collected at crime scenes and may provide valuable evidence in cases with a long postmortem interval (PMI). Here, we collected the puparium of Sarcophaga peregrina (Diptera: Sarcophagidae) (Robineau-Desvoidy, 1830) for 120 days at three temperatures (10 °C, 25 °C, and 40 °C) with the aim to estimate the weathering time of empty puparium. The CHC profiles were analyzed by gas chromatography-mass spectrometry (GC-MS). The partial least squares (PLS), support vector regression (SVR), and artificial neural network (ANN) models were used to estimate the weathering time. This identified 49 CHCs with a carbon chain length between 10 and 33 in empty puparium. The three models demonstrate that the variation tendency of hydrocarbon could be used to estimate the weathering time, while the ANN models show the best predictive ability among these three models. This work indicated that puparial hydrocarbon weathering has certain regularity with weathering time and can gain insight into estimating PMI in forensic investigations.