bluuebunny/crossref_metadata_2025 huggingface dataset:
Marine mammal range and depth estimation using non-separated multipath propagation
Authors: Barazzutti Amelie , GERVAISE Cédric , D. SEGER Kerri , THODE Aaron , Urbán R. Jorge , Martínez-Loustalot Pamela , Jiménez-López M. Esther , López-Arzate Diana , I. MARS Jérôme
Published: May 2016

In passive acoustic monitoring, source localization using multipath propagation can be challenging whenever the source-receiver configuration leads to unresolved paths. Here, we propose a single-hydrophone method to estimate the range of a source based on two steps. First, we define a time deformation operator (e.g., Bonnel et al. 2014) to estimate the signal’s impulse response (IR). Each group of paths, when warped at its time of arrival, is transformed into a tone that corresponds to a peak in the IR, which can be isolated in the warped time-frequency domain, permitting a significant improvement of the time resolution of the multipath, or groups of multipath. Next, relative arrival times are used to estimate the source range and depth. When only groups of paths are resolved, the identity of the paths constituting the group remains unknown, preventing the use of classical localization methods. To overcome this critical limitation, we apply an approach based on the characterization of groups of paths to estimate source location. We evaluate the method’s performance on synthesized data, and examine its potential use on humpback whale low-frequency modulated calls using data collected off Cabo San Lucas in 2013.
Acoustic trajectory corrections to improve mapping of moving sources
Authors: Oudompheng Benoit , Lamotte Lucille , Nicolas Barbara
Published: May 2016

In the context of pass-by experiments, moving-source mapping is classically performed using the extension of conventional beamforming to moving sources: beamforming-MS. The main issue of moving-source mapping is the knowledge of the trajectory of the moving vehicle that contains the sources. This trajectory is mandatory to use the beamforming-MS. Indeed, trajectory errors induce localization artifacts in beamforming results, which can degrade beamforming-MS performance and bias physical interpretations of the localization results. This paper suggests an original method to acoustically correct trajectography mismatches, using a first beamforming-MS computation and spatial correlations, in order to improve moving-source mapping results. Experimental results of aerial pass-by experiments demonstrate the improvements to the mapping results using this trajectory correction.
Intensity filtering of acoustic sensor signals for multi-target tracking
Authors: Xiong Sihan , Damarla Thyagaraju , Ray Asok
Published: May 2016

This paper addresses tracking of closely spaced moving vehicles by using passive acoustic signals. A multiple signal classification algorithm has been applied to estimate the bearing of targets from acoustic sensor signals. Field data from several sensor arrays have been used to reduce estimation variance in intensity filtering, which is performed on the bearing data with a sequential Monte Carlo method. Performance of the algorithm in terms of estimation of number of targets and their tracks will be presented using actual field data.
Using ambient noise correlations for relocating drifting sensor networks
Authors: Nichols Brendan , Martin James , Verlinden Chris , Sabra Karim G.
Published: May 2016

A drifting sensor network, such as hydrophones mounted on autonomous underwater vehicles or drifting buoys, can be used as a random volumetric array for locating underwater acoustic sources. However, navigational uncertainties of mobile platforms underwater limit the positioning accuracy of their acoustic sensors. Precise positioning is required to perform coherent processing for sound source localization using this random volumetric array. It has been shown that ambient ocean noise correlations between fixed receivers can provide additional inter-element distance information to perform array element self-localization [Sabra et al., IEEE J.Ocean Eng., 30 (2005)]. An extension of this approach for an array of drifting sensors will be proposed by optimizing the required averaging duration to account for sensor drift motion. Performance of this proposed approach will be demonstrated using at-sea data collected in the Long Island Sound.
Soundscape analysis in the Southern Ocean using elephant seals as acoustic glider of opportunity
Authors: Cazau Dorian , Bonnel Julien , Le Bras Yves , Guinet Christophe
Published: May 2016

The underwater ambient sound field contains quantifiable information about the physical and biological marine environment. Since 2011, we have been annually collecting underwater data over the migratory routes of bio-logged Southern Elephant Seal (SES). As done with classical underwater gliders, we extract from these data very high resolution (approximately 30 min/400 m) ocean ambient noise measurements. In this conference, we present an overall picture of the low-to-medium frequency (10–6000 Hz) ambient noise distribution and its variability in time and space at a regional scale within the Indian Ocean. We detail our methodology to extract robustly the measurements usually performed on ocean ambient noise, such as sound pressure level over different frequency bands and their statistical percentiles. Also, we present our first attempts of exploiting acoustic recordings from bio-logged SES to infer surface wind speed. Wind maps from the ASCAT satellite (IFREMER, France) were used to study correlation relations between surface wind speed and acoustic content (e.g., the ratio of sound pressure levels at 1 and 6 kHz). In complement, we test SVM and Neural Network methods to estimate the presence of different classes of winds (e.g., below and above 10 m/s) from underwater ocean noise.
Identifying frequency and temporal characteristics of ambient noise using correlation matrices
Authors: Nichols Stephen , Bradley David L.
Published: May 2016

Long-term ambient noise recordings contain an immense amount of information which quickly becomes cumbersome to analyze fully and efficiently. Correlation matrices provide a promising approach to identifying and isolating the active source mechanisms in ambient noise datasets. By comparing the noise levels in different frequency bands, frequency regions which tend to change together are identified, pointing toward either one common source or multiple related sources for the identified frequency bands. An attempt at simplifying the frequency and temporal information provided by series of correlation matrices is presented, utilizing data recorded by the Comprehensive Nuclear-Test Ban Treaty Organization’s hydroacoustic monitoring system.
Amazon rainforest to get a growth check
Authors: Grossman Daniel
Published: May 2016

Ambitious experiment will test whether rising CO
2
will boost the tropical carbon sink.
A reboot for wave energy
Authors: Stokstad Erik
Published: May 2016

U.K. engineers and funders take stock of failures as they design new prototypes.
Comment on “Cycling Li-O
2
batteries via LiOH formation and decomposition”
Authors: Viswanathan Venkatasubramanian , Pande Vikram , Abraham K. M. , Luntz Alan C. , McCloskey Bryan D. , Addison Dan
Published: May 2016

Based on a simple thermodynamic analysis, we show that iodide-mediated electrochemical decomposition of lithium hydroxide (LiOH) likely occurs through a different mechanism than that proposed by Liu
et al
. (Research Article, 30 October 2015, p. 530). The mismatch in thermodynamic potentials for iodide/triiodide (I
−
/I
3
−
) redox and O
2
evolution from LiOH implies a different active iodine/oxygen electrochemistry on battery charge. It is therefore possible that the system described in Liu
et al
. may not form the basis for a rechargeable lithium-oxygen (Li-O
2
) battery.
Response to Comment on “Cycling Li-O
2
batteries via LiOH formation and decomposition”
Authors: Liu Tao , Kim Gunwoo , Carretero-González Javier , Castillo-Martínez Elizabeth , Grey Clare P.
Published: May 2016

We described a lithium-oxygen (Li-O
2
) battery comprising a graphene electrode, a dimethoxyethane-based electrolyte, and H
2
O and lithium iodide (LiI) additives, lithium hydroxide (LiOH) being the predominant discharge product. We demonstrate, in contrast to the work of Shen
et al.
, that the chemical reactivity between LiOH and the triiodide ion (I
3
–
) to form IO
3
–
indicates that LiOH can be removed on charging; the electrodes do not clog, even after multiple cycles, confirming that solid products are reversibly removed.
Draft Genome Sequences of Seven Thermophilic Spore-Forming Bacteria Isolated from Foods That Produce Highly Heat-Resistant Spores, Comprising
Geobacillus
spp., Caldibacillus debilis, and Anoxybacillus flavithermus
Authors: Berendsen Erwin M. , Wells-Bennik Marjon H. J. , Krawczyk Antonina O. , de Jong Anne , van Heel Auke , Holsappel Siger , Eijlander Robyn T. , Kuipers Oscar P.
Published: May 2016

Here, we report the draft genomes of five strains of
Geobacillus spp.
, one
Caldibacillus debilis
strain, and one draft genome of
Anoxybacillus flavithermus
, all thermophilic spore-forming Gram-positive bacteria.
Complete Genome Sequences of Three African Foot-and-Mouth Disease Viruses from Clinical Samples Isolated in 2009 and 2010
Authors: Van Borm Steven , Rosseel Toon , Haegeman Andy , Fana Mpolokang Elliot , Seoke Latoa , Hyera Joseph , Matlho George , Vandenbussche Frank , De Clercq Kris
Published: May 2016

The complete genome sequences of three foot-and-mouth disease viruses (one virus of each serotype SAT1, SAT2 and O) were directly sequenced from RNA extracted from clinical bovine samples, demonstrating the feasibility of full-genome sequencing from strong positive samples taken from symptomatic animals.
Synchronous quadriceps tendon rupture and unilateral ACL tear in a weightlifter, associated with anabolic steroid use
Authors: Fenelon Christopher , Dalton David M , Galbraith John G , Masterson Eric L
Published: May 2016

Synchronous quadriceps tendon rupture is rare. A 29-year-old man, an amateur weight lifter, taking androgenic-anabolic steroids (AAS), developed sudden onset bilateral pain and swelling of his anterior thighs when attempting to squat 280 kg (620 lb). Examination revealed gross swelling superior to the patella and palpable gaps in both quadriceps tendons. He underwent successful operative repair. MRI revealed a partial tear of the anterior cruciate ligament (ACL) of the right knee. This was not reconstructed. Only a few case reports of the association between AAS and quadriceps rupture exist in the literature, with none to the best of our knowledge in the past 10 years. ACL rupture coexisting is very rare, with only two reported cases.
Simple Interventions Improve the Quality of a Missed Lab Appointment Process
Authors: Mookadam Martina , Grover Michael , Pullins Chris , Winscott Mary , Pierce Susan
Published: May 2016

Simple interventions resolve the problem of missed lab appointments.

It is essential that patients complete ordered laboratory studies. This maintains clinical quality and, potentially, keeps patients safe from harm. In our academic family medicine practice, baseline data demonstrated patients completed 94.7% of labs as ordered (26850/28348 patients per year) while 1498 (5.3%) did not. Our baseline patient reminder process, a mail or portal based generic letter, resulted in only 449 (30%) of patients ultimately completing them (1049 [70%] did not). Our baseline system was 96.3 % reliable. This process did not allow for provider review or input, and was not personalized for patients.

We designed a quality improvement project involving three PDSA (Plan, Do, Study, and Act) cycles of about two months each. Desk staff created weekly reports of unresolved lab orders. A message in the electronic medical record (EMR) solicited provider input. Providers could elect to cancel studies (if already completed, reordered, or no longer clinically indicated) or have the patient receive a personalized reminder, including provider name and associated diagnoses. This reminder was sent by patient portal secure messaging (if an account existed) or with a mailed letter. These interventions resulted in 98.8 % process reliability. The frequency of unresolved lab orders decreased from 70% at baseline to 25%.

In the second PDSA cycle, we contacted patients by the portal only if there was evidence of an active account. Otherwise, they were contacted by telephone. Patients without a portal account continued to receive a letter by mail. These modified processes resulted in an overall reliability rate of 99.2%. The frequency of unresolved lab orders decreased to 17%.

A final PDSA cycle utilized only telephone contact with patients with unresolved lab orders. Schedulers offered patients a choice of appointment dates if they spoke personally. Otherwise, they were left messages with a future lab appointment date two weeks later.Overall process reliability now increased to 100%. The frequency of unresolved lab orders decreased to 0%.

Our interventions resulted in increased system reliability.Provider input was not perceived as burdensome. Desk staff work effort was not increased.Telephone patient contact resulted in more frequent lab order completion than other methods.
Introducing routine HIV screening for patients on an internal medicine residency inpatient service: a quality improvement project
Authors: Padrnos Leslie J , Barr Patrick J , Klassen Christine L , Fields Heather E , Azadeh Natalya , Mendoza Neil , Saadiq Rayya A , Pauwels Emanuel M , King Christopher S , Chung Andrew A , Sakata Kenneth K , Blair Janis E
Published: May 2016

The US Centers for Disease Control and Prevention (CDC) recommend human immunodeficiency virus (HIV) screening for all persons aged 13 to 64 years who present to a health care provider. We sought to improve adherence to the CDC guidelines on the Internal Medicine Resident Hospital Service. We surveyed residents about the CDC guidelines, sent email reminders, provided education, and engaged them in friendly competition. Credit for guideline adherence was awarded if an offer of HIV screening was documented at admission, if a screening test was performed, or if a notation in the resident sign out sheet indicated why screening was not performed.

We examined HIV screening of a postintervention group of patients admitted between August 8, 2012, and June 30, 2013, and compared them to a preintervention group admitted between August 1, 2011, and June 30, 2012. Postintervention offers of HIV screening increased significantly (7.9% [44/559] vs 55.5% [300/541]; P<.001), as did documentation of residents' contemplation of screening (8.9% [50/559] vs 67.5% [365/541]; P<.001). A significantly higher proportion of HIV screening tests was ordered postintervention (7.7% [43/559] vs 44.4% [240/541]; P<.001). Monthly HIV screening documentation ranged from 0% (0/53) to 17% (9/53) preintervention, whereas it ranged from 30.6% (11/36) to 100% (62/62) postintervention.

HIV screening adherence can be improved through resident education, friendly competition, and system reminders. Barriers to achieving sustained adherence to the CDC guidelines include a heterogeneous patient population and provider discomfort with the subject.
Exploring a new ultrasound score as a clinical predictive tool in patients with rheumatoid arthritis starting abatacept: results from the APPRAISE study
Authors: D'Agostino Maria-Antonietta , Boers Maarten , Wakefield Richard J , Berner Hammer Hilde , Vittecoq Olivier , Filippou Georgios , Balint Peter , Möller Ingrid , Iagnocco Annamaria , Naredo Esperanza , Østergaard Mikkel , Gaillez Corine , Le Bars Manuela
Published: May 2016

Objectives

To explore whether changes in a composite (power Doppler/greyscale ultrasound (PDUS)) synovitis score, developed by the OMERACT-EULAR-Ultrasound Task Force, predict disease activity outcomes in rheumatoid arthritis (RA).

Methods

Patients with RA who were methotrexate inadequate responders starting abatacept were evaluated. Individual joint PDUS scores were combined in the Global OMERACT-EULAR Synovitis Score (GLOESS) for metacarpophalangeal joints (MCPs) 2–5, all joints (22 paired) and a reduced (9 paired) joint set. The predictive value of changes in GLOESS at week 1–16 evaluations for clinical status and response (Disease Activity Score (DAS)28 (C reactive protein, CRP) <2.6; DAS28(CRP) ≤3.2; DAS28(CRP) ≥1.2 improvement) up to week 24, and correlations between DAS28 and GLOESS were assessed.

Results

Eighty-nine patients completed the 24-week treatment period. Changes in GLOESS (MCPs 2–5) from weeks 1 to 16 were unable to predict DAS28 outcomes up to week 24. However, significant improvements in GLOESS (MCPs 2–5) were observed at week 12 in patients with DAS28 ≥1.2 improvement at week 24 versus those who did not achieve that clinical response. In patients achieving DAS28 ≥1.2 improvement or DAS28 ≤3.2 at week 24, changes in GLOESS (22 and 9 paired joint sets) were greater in patients who already achieved DAS28 ≥1.2 at week 12 than in those who did not. No significant correlations were found between changes in DAS28 and GLOESS definitions at any time point.

Conclusions

PDUS was not correlated with clinical status or response as measured by DAS28-derived criteria, and PDUS changes were not predictive of clinical outcome. The discrepancies require further exploration.

Trial registration number

NCT00767325; Results.
Thinking large
Authors: Devries Egbert
Published: May 2016

Egbert Devries was brought up on a farm in the Netherlands and large animal medicine has always been his area of interest. After working in UK practice for 12 years he joined CVS and was soon appointed large animal director with responsibility for building a stronger large animal practice base
“Weighing” the effects of exercise and intrinsic aerobic capacity: are there beneficial effects independent of changes in weight?
Authors: Thyfault John P. , Wright David C.
Published: May 2016

It has been known for centuries that regularly performed exercise has beneficial effects on metabolic health. Owing to its central role in locomotion and the fact that it accounts for a large majority of whole-body glucose disposal and fatty acid oxidation, the effects of exercise on skeletal muscle has been a central focus in exercise physiology research. With this being said it is becoming increasingly well recognized that both adipose tissue and liver metabolism are robustly modified by exercise, especially in conditions of obesity and insulin resistance. One of the difficult questions to address is if the effects of exercise are direct or occur secondary to exercise-induced weight loss. The purpose of this review is to highlight recent work that has attempted to tease out the protective effects of exercise, or intrinsic aerobic capacity, against metabolic and inflammatory challenges as it relates to the treatment and prevention of obesity and insulin resistance. Recent studies reporting improvements in liver and adipose tissue insulin action following a single bout of exercise will also be discussed. The research highlighted in this review sheds new insight into protective, anti-inflammatory effects of exercise that occur largely independent of changes in adiposity and body weight.
Refining 2 km of Ordovician chronostratigraphy beneath Anticosti Island utilizing integrated chemostratigraphy
Authors: McLaughlin Patrick I. , Emsbo Poul , Desrochers André , Bancroft Alyssa , Brett Carlton E. , Riva John F. , Premo Wayne , Neymark Leonid , Achab Aicha , Asselin Esther , Emmons M. Matthew
Published: May 2016

New high-resolution chemostratigraphy, in combination with updated biostratigraphy, refines the chronostratigraphic resolution of the nearly 2 km thick Ordovician section below Anticosti Island. A total of 1414 horizons, spaced at 1.0–1.5 m intervals, were sampled from the New Associated Consolidated Paper (NACP) drill core and analyzed for major and trace elemental composition by portable X-ray fluorescence analyzer (pXRF). Select micrite and calcareous shale powders were then analyzed for δ13Ccarb (number of samples, N = 364) and 87Sr/86Sr (N = 25). Our results indicate a Floian to early Darriwilian (F3–Dw1) age for the Romaine Formation, a middle Darriwilian to Sandbian (Dw2–Sa1) age for the Mingan Formation, a lower to mid-Katian (Ka1–Ka2) age for the Macasty Formation, an upper Katian (Ka3) age for the lower Vauréal Formation, an uppermost Katian (Ka4) age for the upper Vauréal, and a Hirnantian (H1) age for the Ellis Bay Formation. This integrated chemostratigraphic and biostratigraphic synthesis establishes the position of numerous unconformities, the duration of the intervening depositional sequences, and rates of sedimentation.
Construction of hyperbolic hypersurfaces of low degree in ℙn(ℂ)
Authors: Huynh Dinh Tuan
Published: May 2016

We construct families of hyperbolic hypersurfaces [Formula: see text] of degree [Formula: see text].
Rationally integrable vector fields and rational additive group actions
Authors: Dubouloz Adrien , Liendo Alvaro
Published: May 2016

We characterize rational actions of the additive group on algebraic varieties defined over a field of characteristic zero in terms of a suitable integrability property of their associated velocity vector fields. This extends the classical correspondence between regular actions of the additive group on affine algebraic varieties and the so-called locally nilpotent derivations of their coordinate rings. Our results lead in particular to a complete characterization of regular additive group actions on semi-affine varieties in terms of their associated vector fields. Among other applications, we review properties of the rational counterpart of the Makar–Limanov invariant for affine varieties and describe the structure of rational homogeneous additive group actions on toric varieties.
First principles study of the structural, electronic and optical properties of crystalline o-phenanthroline
Authors: Nejatipour Hajar , Dadsetani Mehrdad
Published: May 2016

In a comprehensive study, structural properties, electronic structure and optical response of crystalline o-phenanthroline were investigated. Our results show that in generalized gradient approximation (GGA) approximation, o-phenanthroline is a direct bandgap semiconductor of 2.60 eV. In the framework of many-body approach, by solving the Bethe–Salpeter equation (BSE), dielectric properties of crystalline o-phenanthroline were studied and compared with phenanthrene. Highly anisotropic components of the imaginary part of the macroscopic dielectric function in o-phenanthroline show four main excitonic features in the bandgap region. In comparison to phenanthrene, these excitons occur at lower energies. Due to smaller bond lengths originated from the polarity nature of bonds in presence of nitrogen atoms, denser packing, and therefore, a weaker screening effect, exciton binding energies in o-phenanthroline were found to be larger than those in phenanthrene. Our results showed that in comparison to the independent-particle picture, excitonic effects highly redistribute the oscillator strength.
A Multi-Scale Cascaded Hierarchical Model for Image Labeling
Authors: Xiao Degui , Chen Qilei , Li Shanshan
Published: May 2016

Image labeling is an important and challenging task in the area of graphics and visual computing, where datasets with high quality labeling are critically needed. In this paper, based on the commonly accepted observation that the same semantic object in images with different resolutions may have different representations, we propose a novel multi-scale cascaded hierarchical model (MCHM) to enhance general image labeling methods. Our proposed approach first creates multi-resolution images from the original one to form an image pyramid and labels each image at different scale individually. Next, it constructs a cascaded hierarchical model and a feedback circle between image pyramid and labeling methods. The original image labeling result is used to adjust labeling parameters of those scaled images. Labeling results from the scaled images are then fed back to enhance the original image labeling results. These naturally form a global optimization problem under scale-space condition. We further propose a desirable iterative algorithm in order to run the model. The global convergence of the algorithm is proven through iterative approximation with latent optimization constraints. We have conducted extensive experiments with five widely used labeling methods on five popular image datasets. Experimental results indicate that MCHM improves labeling accuracy of the state-of-the-art image labeling approaches impressively.
CHEMICAL COMPOSITION STUDY OF VANADIUM PENTOXIDE XEROGELS DOPED BY BOVINE ALBUMIN
Authors: SEREIKA R. , KACIULIS S. , MEZZI A. , BRUCALE M.
Published: May 2016

Metal–bioorganic compounds of vanadium pentoxide and bovine serum albumin (BSA) (Fraction V) were obtained by using sol–gel method. Series of the samples (BSA)xV2O[Formula: see text]H2O, where [Formula: see text], 0.01 and 0.001, were originally produced by the synthesis of vanadium pentoxide xerogels and subsequent blending with water-dissolved BSA in appropriate molar ratios. It was evident that the gelation process does not occur for [Formula: see text]. For the X-ray photoelectron spectroscopy (XPS) studies, the thin layers of these materials were prepared by drying the gel onto the glass and mica substrates. The surface morphology of the samples was characterized by scanning electron microscopy (SEM) and atomic force microscopy (AFM) techniques. It follows from the analysis of experimental XPS spectra of (BSA)xV2O[Formula: see text]H2O that the nitrogen ions in pure albumin and in (BSA)[Formula: see text]V2O[Formula: see text]H2O are present in imine, amine and protonated amine groups. The additional protonated amine arises when the concentration of albumin in (BSA)xV2O[Formula: see text]H2O is low ([Formula: see text]). Increasing the amount of albumin results in decrease of the number of oxygen ions bonded to vanadium. At the same time (with increase of albumin), the component of oxygen bounded to carbon and nitrogen is increasing. In the samples with greater amount of albumin, the reduction of vanadium ions occurs. This means that the trivalent and tetravalent vanadium ions are present together with pentavalent ones.
Appraisal of Knowledge Object Use via a Three-Phase Flow Profile
Authors: Wu Chien-Hsing , Kao Shu-Chen
Published: May 2016

The quality of a knowledge base does not depend mainly on the number of knowledge objects (KOs) that are available, but on the number of objects that are actually shared, combined, internalised, adopted, or even validated to be value creatable. In support of this goal, knowledge management has paid increasing attention to the most valued KO of knowledge base for a variety of managerial decisions. This paper proposes a model called knowledge object use appraisal model (KOUAM) based on knowledge flow profile to help derive the appraisal of KO use in knowledge base. The KOUAM considers three phases, namely, incubation, adoption, and validation as the appraisal base. A demonstrated example is presented and evaluation of the proposed KOUAM is acceptable. Feedback and managerial implications are also addressed.
Recent advances in C–H bond aminations catalyzed by ruthenium porphyrin complexes
Authors: Intrieri Daniela , Carminati Daniela Maria , Gallo Emma
Published: May 2016

This review deals with the use of ruthenium porphyrin complexes to catalyze hydrocarbon aminations. This class of versatile porphyrin catalysts are able to activate different nitrogen sources, such as iminoiodinanes and organic azides, and promote the synthesis of a variety of aza-derivatives. Many synthetic procedures have been discussed as well as catalytic mechanisms involved in order to give an overview on the use of ruthenium porphyrins to promote nitrene transfer reactions yielding aminated derivatives.
A study of nonlinear age-structured population models
Authors: Mohyud-Din Syed Tauseef , Waheed A. , Rashidi M. M.
Published: May 2016

This paper presents a novel analysis for the solution of nonlinear age-structured problem which is of extreme importance in biological sciences. The presented model is very useful but quite complicated. Modified variational iteration method (MVIM) coupled with auxiliary parameter is used to cope with the complexity of the model which subsequently shows better results as compared to some existing results available in literature. Furthermore, an appropriate way is used for the identification of auxiliary parameter by means of residual function. Numerical examples are presented for the analysis of the proposed algorithm. Graphical results along with the discussions re-confirm the efficiency of proposed algorithm. The work proposes a new algorithm where He’s polynomials and an auxiliary parameter are merged with correction functional. The suggested scheme is implemented on nonlinear age-structured population models. Graphs are plotted for the residual function that reflects the accuracy and convergence of the presented algorithm.
Ferroelectric HfO2-based materials for next-generation ferroelectric memories
Authors: Fan Zhen , Chen Jingsheng , Wang John
Published: May 2016

Ferroelectric random access memory (FeRAM) based on conventional ferroelectric perovskites, such as Pb(Zr,Ti)O3 and SrBi2Ta2O9, has encountered bottlenecks on memory density and cost, because those conventional perovskites suffer from various issues mainly including poor complementary metal-oxide-semiconductor (CMOS)-compatibility and limited scalability. Next-generation cost-efficient, high-density FeRAM shall therefore rely on a material revolution. Since the discovery of ferroelectricity in Si:HfO2 thin films in 2011, HfO2-based materials have aroused widespread interest in the field of FeRAM, because they are CMOS-compatible and can exhibit robust ferroelectricity even when the film thickness is scaled down to below 10 nm. A review on this new class of ferroelectric materials is therefore of great interest. In this paper, the most appealing topics about ferroelectric HfO2-based materials including origins of ferroelectricity, advantageous material properties, and current and potential applications in FeRAM, are briefly reviewed.
АВТОДЕРМОПЛАСТИКА ТА ВАКУУМНА ТЕРАПІЯ РАН У ХВОРИХ НА СИНДРОМ ДІАБЕТИЧНОЇ СТОПИ
Authors: Herasymchuk P. O. , Vlasenko V. H. , Pavlyshyn A. V. , Fira D. B.
Published: May 2016

РЕЗЮМЕ. На основі обстеження та лікування 142 хворих на ускладнені форми синдрому діабетичної стопи
вивчено вплив вакуумної терапії на підготовку ран до автодермопластики. Доведено, що вакуумна терапія
ран дозволяє майже вдвічі зменшити число етапних некректомій та скоротити терміни підготовки ран до
автодермопластики у хворих з невропатично-інфікованою формою ураження в середньому на (3,4±1,2) дні,
у хворих з ішемічно-гангренозною формою – в середньому на (3,96±1,7) дні. Це дозволяє в зменшити терміни
стаціонарного лікування хворих у середньому на (4,2±1,8) ліжко-дні, що має не тільки медичне, а і соціальне
значення.

КЛЮЧОВІ СЛОВА: синдром діабетичної стопи, вакуумна терапія.
РАННЯ ДІАГНОСТИКА АЛКОГОЛЬНОЇ ЗАЛЕЖНОСТІ В ПРАКТИЦІ СІМЕЙНОГО ЛІКАРЯ
Authors: Sosin І. K. , Skvira I. M. , Mitsura V. M. , Chuyev Yu. F. , Honcharova O. Yu.
Published: May 2016

РЕЗЮМЕ. Рання діагностика алкогольної залежності є однією з найважливіших і найактуальніших завдань
сучасної наркології. Залучення до вирішення цієї проблеми лікарів сімейної практики дозволить на етапі
обстеження пацієнтів з гепатопатичною патологією виявити потенційну когорту осіб, які мають симптоми
алкогольної залежності. Своєчасна консультація лікаря нарколога дасть можливість підтвердити або виключити
наявність наркопатології, визначити лікувальну програму. Обстежено 255 пацієнтів з гепатопатичними розладами,
які звернулися за медичною допомогою в загальносоматичні лікувальні установи. На основі даних клінічного
інтерв'ю, психодіагностичного тестування, лабораторного дослідження розроблено комплексний алгоритм
виявлення алкогольної залежності у пацієнтів з хронічними захворюваннями печінки.

КЛЮЧОВІ СЛОВА: рання діагностика, алкогольна залежність, сімейний лікар.
КЛІНІЧНИЙ ПЕРЕБІГ ІНФАРКТУ МІОКАРДА З АНГІОГРАФІЧНО ІНТАКТНИМИ ТА МАЛОЗМІНЕНИМИ ВІНЦЕВИМИ АРТЕРІЯМИ У ЖИТЕЛІВ ГІРСЬКИХ ТА РІВНИННИХ НАСЕЛЕНИХ ПУНКТІВ ЗАКАРПАТТЯ
Authors: Ustych O. V.
Published: May 2016

РЕЗЮМЕ. Проаналізовані дані пацієнтів з інфарктом міокарда на фоні ангіографічно нормальних та незначно
змінених вінцевих артерій у жителів різних висотних регіонів Закарпаття. Горяни були молодшими та мали
більші розміри задньої стінки лівого шлуночка, правого шлуночка та лівого передсердя. Гірські мешканці рідше
зверталися за медичною допомогою та частіше навіть не лікувалися при наявності загрозливих симптомів з боку
серцево-судинної системи.

КЛЮЧОВІ СЛОВА: інфаркт міокарда, інтактні вінцеві артерії, незначно змінені вінцеві артерії, гірські регіони.
Crise da água na região metropolitana de São Paulo – 2013/2015
Authors: Jacobi Pedro Roberto , Cibim Juliana Cassano , Souza Alexandre Nascimento
Published: May 2016

A diminuição dos índices pluviométricos na região sudeste do Brasil apresentavam um cenário previsível de escassez hídrica no ano de 2015. Diante da negação da possível crise, a gestão hídrica restou prejudicada. A situação crítica e a morosidade na proposição de medidas efetivas para minimizar a crise fazem da Região Metropolitana de São Paulo uma área crítica em relação à qualidade e quantidade de água. Da observação dessa nova condição, o presente artigo, além de contextualizar a crise, se propõe a apresentar propostas para gestão dos recursos hídricos no estado.
Type 1
Deiodinase
Regulates
ApoA-I
Gene Expression and ApoA-I Synthesis Independent of Thyroid Hormone Signaling
Authors: Liu Jing , Hernandez-Ono Antonio , Graham Mark J. , Galton Valerie Anne , Ginsberg Henry N.
Published: May 2016

Objective—

Plasma levels of high-density lipoprotein cholesterol (HDL-C) and apolipoprotein A-I (ApoA-I) are reduced in individuals with defective insulin signaling. Initial studies using liver-specific insulin receptor (InsR) knockout mice identified reduced expression of type 1 deiodinase (
Dio1
) as a potentially novel link between defective hepatic insulin signaling and reduced expression of the
ApoA-I
gene. Our objective was to examine the regulation of
ApoA-I
expression by
Dio1
.

Approach and Results—

Acute inactivation of
InsR
by adenoviral delivery of Cre recombinase to
InsR
floxed mice reduced HDL-C and expression of both
ApoA-I
and
Dio1
. Overexpression of
Dio1
in
InsR
knockout mice restored HDL-C and ApoA-I levels and increased the expression of
ApoA-I
.
Dio1
knockout mice had low expression of
ApoA-I
and reduced serum levels of HDL-C and ApoA-I. Treatment of C57BL/6J mice with antisense to
Dio1
reduced
ApoA-I
mRNA, HDL-C, and serum ApoA-I. Hepatic 3,5,3′-triiodothyronine content was normal or elevated in
InsR
knockout mice or
Dio1
knockout mice. Knockdown of either
InsR
or
Dio1
by siRNA in HepG2 cells decreased the expression of
ApoA-I
and ApoA-I synthesis and secretion.
siRNA
knockdown of
InsR or Dio1
decreased activity of a region of the
ApoA-I
promoter lacking thyroid hormone response elements (region B). Electrophoretic mobility shift assay demonstrated that reduced
Dio1
expression decreased the binding of nuclear proteins to region B.

Conclusions—

Reductions in
Dio1
expression reduce the expression of
ApoA-I
in a 3,5,3′-triiodothyronine-/thyroid hormone response element–independent manner.
Outcome After Thrombectomy and Intravenous Thrombolysis in Patients With Acute Ischemic Stroke
Authors: Minnerup Jens , Wersching Heike , Teuber Anja , Wellmann Jürgen , Eyding Jens , Weber Ralph , Reimann Gernot , Weber Werner , Krause Lars Udo , Kurth Tobias , Berger Klaus ,   for the REVASK Investigators, Homberg V. , Petrovitch A. , Heuser L. , Mönnigs P. , Krogias C. , Wallner B. , Hennigs S. , Ahlers A. , Sahl H. , Ranft A. , Dobis C. , Brassel F. , Nolden-Koch M. , Schmitt H. , Chapot R. , Nordmeyer H. , Schlamann M. , Weimar C. , Busch F. , Busch E.W. , Sigges E. , Ruf H. , Wohlfahrt K. , Karatschai R. , Klein B. , Höhle T. , Haass A. , Nasreldein A. , Büchele B. , Gahn G. , Sterker M. , Hantel T. , Krämer C. , Henningsen H. , Adelt I. , König M. , Schmidt C. , Hofmann A. , Niederstadt T. , Unrath M. , Rehfeldt T. , Fauser B. , Pfeiffer A. , Lowens S. , Stögbauer F. , Staudacher T. , Erdmann P. , Grotemeyer K.H. , Spüntrup E. , Bücke P. , Wienecke P. , Faiss J. , Wolzik-Großmann M. , Brune N. , Isenmann S. , Thomas C. , Mucha D.
Published: May 2016

Background and Purpose—

In patients with ischemic stroke, randomized trials showed a better functional outcome after endovascular therapy with new-generation thrombectomy devices compared with medical treatment, including intravenous thrombolysis. However, effects on mortality and the generalizability of results to routine clinical practice are uncertain.

Methods—

In a prospective observational register-based study patients with ischemic stroke treated either with thrombectomy, intravenous thrombolysis, or their combination were included. Primary outcome was the modified Rankin scale score (0 [no symptoms] to 6 [death]) at 3 months. Ordinal logistic regression was used to estimate the common odds ratio as treatment effects (shift analysis). Propensity score matching was applied to compare patients treated either with intravenous thrombolysis alone or with intravenous thrombolysis plus thrombectomy.

Results—

Among 2650 recruited patients, 1543 received intravenous thrombolysis, 504 underwent thrombectomy, and 603 received intravenous thrombolysis in combination with thrombectomy. Later time-to-treatment was associated with worse outcomes among patients treated with thrombectomy plus thrombolysis. In 241 pairs of propensity score–matched patients with a proximal intracranial occlusion, thrombectomy plus thrombolysis was associated with improved functional outcome (common odds ratio, 1.84; 95% confidence interval, 1.32–2.57), and reduced mortality (15% versus 33%;
P
<0.0001) compared with intravenous thrombolysis alone. Results were similar in various sensitivity analyses accounting for missing outcome data and different analytic methods.

Conclusions—

Results from this large prospective registry show that also in routine clinical care thrombectomy plus thrombolysis compared with thrombolysis alone improved functional outcome and reduced mortality in patients with ischemic stroke. Earlier treatment was associated with better outcomes.
A phylogeny of Astyanax (Characiformes: Characidae) in Central and North America
Authors: SCHMITTER-SOTO JUAN J.
Published: May 2016

A phylogeny is presented for 34 species of Astyanax, 27 of them once included within A. aeneus or A. fasciatus in Central America and Mexico, based on 52 morphological characters (mostly osteological, but also pigmentation and meristics), with three outgroups. Monophyly is not supported for A. aeneus s. lat., as Brazilian species such as A. fasciatus s. str. and others occur also within that clade. There were only five resolved clades, three of them including both Brazilian and Central American species, one purely Nicaraguan, and one for central-northern Mexico and Texas. Coincidence with previous cladistic hypotheses is only partial. The genus Bramocharax Gill is not recovered, and thus confirmed as a synonym of Astyanax Baird & Girard. The findings point at a more complex biogeographic history of the region than usually recognized.
Five new species of the family Trischistomatidae (Nematoda: Enoplida) from North and Central America, with keys to the species of Trischistoma and Tripylina
Authors: PRADO-VERA IGNACIO CID DEL , FERRIS HOWARD , NADLER STEVEN A.
Published: May 2016

Three new species of Trischistoma and two new species of Tripylina (Trischistomatidae) are described. Trischistoma ripariana n. sp. was collected in the surface organic material and upper rhizosphere soil on a stream bank in Oakville, California, USA. It is characterized by a short, thin body, the vulva at 79–83%, a small index c (17–29) and a short tail, 34–57 µm. Trischistoma corticulensis n. sp. was found in moss on tree bark in a tropical forest at the La Mancha Ecological Institute, Veracruz State, México. The vulva is at 67–73% and the tail is elongate conoid (51–84 µm). Trischistoma helicoformis n. sp. was collected on lichen growing on tree bark near the Carretera Interamericana in Costa Rica. It is characterized by its spiral shape after fixation, the tail length (76–101 µm), a very small index c (10–14.5) and very small sclerotised pieces around the vagina. Tripylina rorkabanarum n. sp. was collected from moss on tree bark in a tropical forest at the La Mancha Ecological Institute. It is characterized by the presence of two cervical setae, the position of the subventral teeth posterior to the dorsal tooth, the absence of sclerotized pieces around the vagina and the distance of the dorsal tooth from the anterior, 10–15 μm. Tripylina iandrassyi n. sp. was collected from soil around a banana tree at the La Mancha Ecological Institute. It is characterized by the presence of a post-uterine sac, well-developed buccal lips, subventral teeth located posterior to the dorsal tooth, one cervical seta in females and two in males, and by spicules not completely surrounded by a muscular sheath.
Amblyceps accari, a new species of torrent catfish (Teleostei: Amblycipitidae) from the Western Ghats of India
Authors: DAHANUKAR NEELESH , RAGHAVAN RAJEEV , ALI ANVAR , BRITZ RALF
Published: May 2016

A new species of torrent catfish, Amblyceps accari, is described from the central region of the Western Ghats of India. The new species differs from all its congeners by having 12 branched anal-fin rays (vs. 7–10 in other Amblyceps, rarely 11 in A. tuberculatum). It differs further from all other species of the genus except A. murraystuarti and A. torrentis in having the adipose fin confluent with the dorsal procurrent part of the caudal fin and by the following combination of characters from all its congeners: jaws unequal with lower jaw weakly-projecting, pectoral spine smooth, adipose-fin origin opposite anal-fin origin, dorsal fin to adipose-fin distance more than one fourth of standard length, adipose fin long with its base more than one-fourth of standard length, and deeply forked caudal fin with minute, poorly developed, centrally projecting hooks on the proximal lepidotrichia of central caudal-fin rays. The discovery of the new species represents the first record of this genus from peninsular India.
S4: An O2R/R2O Infrastructure for Optimizing Satellite Data Utilization in NOAA Numerical Modeling Systems: A Step Toward Bridging the Gap between Research and Operations
Authors: Boukabara Sid A. , Zhu Tong , Tolman Hendrik L. , Lord Steve , Goodman Steven , Atlas Robert , Goldberg Mitch , Auligne Thomas , Pierce Bradley , Cucurull Lidia , Zupanski Milija , Zhang Man , Moradi Isaac , Otkin Jason , Santek David , Hoover Brett , Pu Zhaoxia , Zhan Xiwu , Hain Christopher , Kalnay Eugenia , Hotta Daisuke , Nolin Scott , Bayler Eric , Mehra Avichal , Casey Sean P. F. , Lindsey Daniel , Grasso Louie , Kumar V. Krishna , Powell Alfred , Xu Jianjun , Greenwald Thomas , Zajic Joe , Li Jun , Li Jinliong , Li Bin , Liu Jicheng , Fang Li , Wang Pei , Chen Tse-Chun
Published: May 2016

In 2011, the National Oceanic and Atmospheric Administration (NOAA) began a cooperative initiative with the academic community to help address a vexing issue that has long been known as a disconnection between the operational and research realms for weather forecasting and data assimilation. The issue is the gap, more exotically referred to as the “valley of death,” between efforts within the broader research community and NOAA’s activities, which are heavily driven by operational constraints. With the stated goals of leveraging research community efforts to benefit NOAA’s mission and offering a path to operations for the latest research activities that support the NOAA mission, satellite data assimilation in particular, this initiative aims to enhance the linkage between NOAA’s operational systems and the research efforts. A critical component is the establishment of an efficient operations-to-research (O2R) environment on the Supercomputer for Satellite Simulations and Data Assimilation Studies (S4). This O2R environment is critical for successful research-to-operations (R2O) transitions because it allows rigorous tracking, implementation, and merging of any changes necessary (to operational software codes, scripts, libraries, etc.) to achieve the scientific enhancement. So far, the S4 O2R environment, with close to 4,700 computing cores (60 TFLOPs) and 1,700-TB disk storage capacity, has been a great success and consequently was recently expanded to significantly increase its computing capacity. The objective of this article is to highlight some of the major achievements and benefits of this O2R approach and some lessons learned, with the ultimate goal of inspiring other O2R/R2O initiatives in other areas and for other applications.
A Global Ocean Observing System for Measuring Sea Level Atmospheric Pressure: Effects and Impacts on Numerical Weather Prediction
Authors: Centurioni Luca , Horányi András , Cardinali Carla , Charpentier Etienne , Lumpkin Rick
Published: May 2016

Since 1994 the U.S. Global Drifter Program (GDP) and its international partners cooperating within the Data Buoy Cooperation Panel (DBCP) of the World Meteorological Organization (WMO) and the United Nations Education, Scientific and Cultural Organization (UNESCO) have been deploying drifters equipped with barometers primarily in the extratropical regions of the world’s oceans in support of operational weather forecasting. To date, the impact of the drifter data isolated from other sources has never been studied. This essay quantifies and discusses the effect and the impact of in situ sea level atmospheric pressure (SLP) data from the global drifter array on numerical weather prediction using observing system experiments and forecast sensitivity observation impact studies. The in situ drifter SLP observations are extremely valuable for anchoring the global surface pressure field and significantly contributing to accurate marine weather forecasts, especially in regions where no other in situ observations are available, for example, the Southern Ocean. Furthermore, the forecast sensitivity observation impact analysis indicates that the SLP drifter data are the most valuable per-observation contributor of the Global Observing System (GOS). All these results give evidence that surface pressure observations of drifting buoys are essential ingredients of the GOS and that their quantity, quality, and distribution should be preserved as much as possible in order to avoid any analysis and forecast degradations. The barometer upgrade program offered by the GDP, under which GDP-funded drifters can be equipped with partner-funded accurate air pressure sensors, is a practical example of how the DBCP collaboration is executed. Interested parties are encouraged to contact the GDP to discuss upgrade opportunities.