bluuebunny/crossref_metadata_2025 huggingface dataset:
Using Data Science to Interrogate Transition State Stabilization in Anion-Binding Catalysis for Disulfide Ring-Opening Polymerization
Authors: Zhang Miaomiao , Su Yuming , Du Tianyi , Ding Shihao , Dai Jieyu , Wang Cheng , Liu Yun
Published: January 2025

In nature, enzymes leverage constituent amino acid residues to create catalytic microenvironment for their active sites to effect high reactivity and selectivity. Multicomponent host−guest assemblies have been exploited to mimic enzymatic microenvironments by preorganizing a network of noncovalent interactions. While anion-binding catalysts such as thioureas have gained widespread success in organic transformation and controlled polymerization, evaluation of the participating structural features in the transition state (TS) stabilization remains challenging. Herein, we report the use of data science tools, i.e., a decision-tree-based machine-learning algorithm and Shapley additive explanations (SHAP) analysis, to model reactivity and regioselectivity in a thiourea-catalyzed ring-opening polymerization of 1,2-dithiolanes. Variation of aryl substituent position and electronic characteristics helps reveal key catalyst features involved in the TS stabilization within the catalytically active, multicomponent host−guest complexes. The analysis of feature importance helps explain the reason behind the optimal performance of (pseudo)halogen-substituted catalysts. Furthermore, the structural basis for the unveiled reactivity-regioselectivity trade-off in the catalysis are established.
Photo-induced Vicinal Difunctionalization of Diaryliodonium Salts to Access Bis(tetraphenylphosphonium) Salts
Authors: Wang Yu , Wang Limin , Han Jianwei
Published: January 2025

Vicinal bis(tetraarylphosphonium) salts have scarcely been reported in the literatures. In this study, we demonstrate that visible-light-induced difunctionalization of ortho-trifluoromethylsulfonylated diaryliodonium salts conveniently furnishes symmetric bis(phosphonium) salts without additional catalysts or photo-initiators. The methodology establishes a practical platform for the prep-aration of bis(phosphonium) salts using readily available tertiary phosphines. The bis(tetraarylphosphonium) salts are anticipated to garner wide interest in catalytic and medicinal chemistry.
Comprehensive Study on Solvent Dynamics in Gel Polymer Electrolytes for Lithium-Sulfur Battery
Authors: Gomes Luisa , Dai Huidong , Chambers Daniel , Ribeiro Sanctis Victor , Yang Kevin , Dong Ruizhi , Do Anhtu , Ji Tongtai , Mukerjee Sanjeev
Published: January 2025

Li-Sulfur (Li-S) batteries stand promising as the next-generation energy storage technology but are hindered by sluggish sulfur redox reaction kinetics and sulfur shuttling effect. Many studies tried to address these issues by adopting polycaprolactone (PCL) based gel polymer electrolytes (GPEs), but often overlooked solvent properties, including dielectric constant (ϵ), donor and acceptor numbers (DN and AN), impact performance and prevent the full implementation of GPE-based Li-S batteries. This work compares three distinct electrolytes paired with PCL, namely, dimethoxyethane (DME), dimethyl sulfoxide (DMSO), and tetraethylene glycol dimethyl ether (TEGDME), due to their varied solvent properties, to evaluate their effects on the physical properties of the GPE, Li⁺ transport and solvation, and polysulfide's confinement. The DME-based GPE, with an intermediate DN, exhibited the lowest crystallinity (2.31%), highest ionic conductivity (7.49 mS/cm), and high Li⁺ transference number (0.77), achieving a specific capacity of 795 mAh/g sulfur and an average coulombic efficiency of 97.5% after 120 cycles at C/5, outperforming its competitors. Moreover, operando Raman and UV-Vis spectroscopy confirmed that PCL effectively confines long-chain polysulfides within its network, mitigating the shuttle effect and facilitating reversible polysulfide conversion. These findings highlight that GPEs with moderate DN values and balanced ϵ enhance stability, extend cycle life, and improve rate performance for Li-S batteries, providing unique insights for designing advanced electrolyte systems for practical applications.
H-Tunneling Rotamerization in Glycine Imine
Authors: Drabkin Vladimir D. , Eckhardt André K.
Published: January 2025

Quantum mechanical tunneling governs chemical reactivity at cryogenic temperatures. Here we present the near-infrared (NIR) light-induced generation of a higher energy conformer of glycine imine and its H-tunneling CO bond rotamerization in solid argon (Ar), para-hydrogen (p-H2), and dinitrogen (N2) at cryogenic temperatures. The tunneling half-life for the CO bond rotamerization highly depends on the host matrix and is approximately 5 h in Ar, 18 h in p-H2 and N2. Surprisingly, experiments in p-H2 revealed a much longer half-life than in Ar, indicating the formation of a dinitrogen complex after photolysis of the azide precursor. Deuteration of the carboxylic acid group completely inhibits the CO bond D-tunneling rotamerization. We conducted Wentzel−Kramers−Brillouin (WKB) and canonical variational transition state theory in combination with multidimensional small curvature tunneling corrections (CVT/SCT) tunneling calculations at the B3LYP/cc-pVTZ level of theory. The gas-phase tunneling half-life is 11 h according to the one-dimensional WKB model and 1 h according to the multidimensional CVT/SCT model, both aligning well with our experimental results.
Induced bifunctionality by mechanical blending of OER and ORR active 3D perovskite electrocatalysts for zinc-air batteries
Authors: Sen Sujan , Kumar Anil , Roy Sounak , Mandal Tapas Kumar
Published: January 2025

Bifunctional electrocatalysts for oxygen electrocatalysis are typically developed by combining separate OER and ORR electrocatalysts to form composites, often requiring complex synthesis methods. In this study, we present a simplified approach by mechanical blending of BaSr2CoTiSbO9 (BSCTS), an OER catalyst, with BaSr2MnTiSbO9 (BSMTS), an ORR catalyst, to construct a composite bifunctional electrocatalyst. The DFT calculation supports superior ORR activity of BSMTS due to an uplifted Mn d-band center than the Co d-band and its proximity to the Fermi level, whereas the greater OER activity of BSCTS is due to the uplifted O 2p band center. While microstructural similarity of BSCTS and BSMTS facilitates efficient mixing for composite formation, the mechanical blending avoids intervention of complex synthesis procedures. The resulting bifunctional composite electrocatalyst demonstrates excellent performance with a bifunctional index of 0.72 V and a peak power density of 125 mW/cm2 when used as an air cathode electrocatalyst in Zn-air battery (ZAB). This approach underscores the importance of mechanical blending of microstructurally compatible OER and ORR catalysts in designing practical bifunctional electrocatalysts for zinc-air batteries.
Characterization of the tautomeric equilibrium of molnupiravir, an antiviral for the treatment of COVID-19
Authors: Burgess Samantha , Wang Xiao , Stueber Dirk , Wang Yunyi , Cohen Ryan , Lam Yu-hong , Iuzzolino Luca , Reibarkh Mikhail
Published: January 2025

A combined experimental NMR and DFT computational analysis of molnupiravir, an orally dosed antiviral effective for treatment of patients with COVID-19, determined that the molecule primarily exists as an oxime tautomer both in solution and in solid state. Both Z and E oxime stereoisomers were observed in various solvents, with Z being the major form, consistent with the DFT calculations. An amine form was not detected directly, but the results strongly suggest that it exists as the transient intermediate responsible for the interconversion of E and Z oxime isomers observed in solution. The Z oxime form was identified to be the predominant form in the solid state.
Geometric Orthogonality as a Recipe for Efficient Single-Molecule Charge Generation in Core Substituted NDI Derivatives
Authors: Britton Hugh , Santa Daría Alberto , Lyu Chao , Bučar Dejan-Krešimir , Tabor Alethea , Schroeder Bob , Gómez Sandra , Marin-Beloqui Jose Manuel
Published: January 2025

One of the primary drawbacks of organic materials, compared to their inorganic counterparts in various optoelectronic applications, is their lower charge generation efficiency, which stems from their inherently higher exciton binding energy. Therefore, new out-of-the-box approaches need to be introduced to the field. Herein, we propose a new approach to increase the charge formation of naphthalenediimide (NDI) derivatives by inducing a large torsional angle between the NDI core and the core-attached substituent, deconjugating the resulting extended π-system. To study the extent of this change, transient absorption spectroscopy characterisation has been performed on a set of derivatised NDI molecules where the core-attached substituents have been systematically altered to modulate the resulting torsional angle. The data clearly shows an enhanced charge generation with core-attached substituents from phenyl to anthracenyl which increase in both size and degree of rotational inhibition. This opens the possibility for a new family of NDI materials with implications for a wide range of applications such as photovoltaics, transistors and catalysis.
Electrochemical Tryptophan-Selective Bioconjugation
Authors: Kuroda Ryo , Toyama Eisho , Sugai Tomoya , Imai Maho , Watanabe Kohei , Konoue Natsuki , Maruyama Katsuya , Kondo Mio , Masaoka Shigeyuki , Saitoh Tsuyoshi , Oisaki Kounosuke , Kanai Motomu
Published: January 2025

Bioconjugation reactions are a fundamental synthetic strategy for generating artificial peptides and proteins. Although bioconjugates at hydrophobic amino acid residues can offer superior product homogeneity compared to those at hydrophilic residues, methods to target moderately reactive hydrophobic amino acids under mild and metal-free conditions are limited. In this study, we present the first electrochemically promoted, tryptophan (Trp)-selective bioconjugation that is applicable at the protein scale in a neutral buffer. The unique electrochemical cooperation of two radicals, keto-ABNO and 4-oxo-TEMPO, along with NaBr, was key to accelerating the reaction while simultaneously suppressing both anodic overoxidation of the products and cross-reactivity. Systematic cyclic voltammetry (CV) and UV-visible absorption spectroelectrochemistry (SEC) analyses revealed that these two radicals, which have similar redox potentials but differing steric demands, serve distinct electrochemical roles (as reactant and electrochemical mediator, respectively). Additionally, NaBr was suggested not to function as a redox mediator, but instead likely prevents the decomposition of oxoammonium active species. This electrochemical protocol marks a significant advance toward novel processing techniques for chemically modified biologics.
Polybenzenoid Hydrocarbons in the S1 State: Simple Structural Motifs Predict Electronic Properties and (Anti)Aromaticity
Authors: Khaleel Fatimah , Chakraborty Sabyasachi , Gershoni-Poranne Renana
Published: January 2025

Abstract Polybenzenoid hydrocarbons (PBHs) are widely studied for their semiconductive properties and potential applications in organic electronics and photochemistry. Understanding their behavior in excited states is crucial for optimizing their performance in these applications. Here, we computationally investigate a dataset of 43 unbranched cata-condensed PBHs in their first singlet excited state (S₁), revealing clear correlations between molecular structure and electronic properties. By analyzing these molecules through their annulation patterns—specifically the arrangement of linear (L) and angular (A) tricyclic subunits, and tetracyclic zig-zag (Z) and curve (C) motifs—we establish a predictive hierarchy (L > Z > C > A) for the location of unpaired electrons and Baird-antiaromaticity. This structural approach enables semi-quantitative prediction of key properties including excitation energies, magnetic response, and singlet fission capability. Notably, we find that singlet fission propensity is dependent on both the length of the Longest L sequence and the position of the sequence at the edge of the molecule. These insights, derived from analysis of small tri- and tetracyclic components and validated on larger systems, provide a practical framework for understanding and designing PBH-based materials.
Low-cost optical multi-wavelength sensor for accurate real-time state-of-charge monitoring in vanadium flow batteries
Authors: Maurice Ange A. , Prieto-Díaz Pablo A. , Vera Marcos
Published: January 2025

We presents a novel, low-cost optical sensor for accurate real-time monitoring of state of charge (SoC) and total vanadium concentration in vanadium flow batteries. Using only six discrete wavelengths, the sensor achieves precision comparable to full-spectrum methods while significantly reducing equipment costs and complexity. A general deconvolution method is used to measure both the SoC and the total vanadium concentration in both the posolyte and negolyte, with calibration covering concentrations from 1.2 to 1.8 M. We achieve an overall accuracy of 2.4% for the SoC and 70 mM for the total vanadium concentration. Additionally, an optimization study is proposed to determine the optimal number and placement of spectral channels, providing a basis for designing tailored optical sensors for vanadium electrolytes.
Evans-Polanyi-like models for rapidly predicting barriers of hemicellulose motifs under pyrolysis conditions based on the reactant reactivity parameters
Authors: Ayarde-Henríquez Leandro , Lupi Jacopo , Ballotta Bernardo , Dooley Stephen
Published: January 2025

This work elucidates Evans-Polanyi-like (EPL) relations to rapidly estimate the standard activation enthalpy of three ubiquitous reaction classes playing a central role in hemicellulose pyrolysis: ring-opening, ring contraction, and elimination. These models leverage computationally cheap local and global electron-density-based chemical reactivity descriptors, such as Fukui’s functions (f), electron population of CO bonds (N), and the gross intrinsic strength bond index (Δgpair), evaluated for reactants solely. More than 270 reactions observed in twenty-eight functionalized β-D-xylopyranoses, the hemicellulose building block, are used under the 20-80 % partition scheme for validating-deriving purposes. By using the relatively simple multilinear regression analysis, four EPL are proposed for informing barriers at the M06-2X/6-311++G(d,p), CBS-QB3, G4, and DLPNO-CCSD(T)-F12/cc-pVTZ-F12//M06-2X/6-311++G(d,p), namely, ΔHDFT = –168.82f ̅– 66.28N ̅ + 328.10Δ ̅gpair – 18.80, ΔHCBS = –189.01(f ) ̅– 65.11N ̅ + 266.44Δ ̅gpair + 13.96, ΔHG4 = –184.99f ̅ – 64.85N ̅ + 275.10Δ ̅gpair + 8.52, and ΔHDLPNO = –187.82f ̅ – 72.45N ̅ + 296.14Δ ̅gpair + 7.72, respectively. An adjusted coefficient of determination of 0.80 characterizes all these parametric polynomials. Moreover, MAE and RMSE equal to ≈3.3 and ≈4.1 kcal mol-1 describe the performance of the best-fitting models at DFT and G4. Conversely, the highest values, MAE = 3.6 and RMSE = 4.7 kcal mol-1, are associated with the CBS-QB3 level. The benchmarking of the computed activation enthalpies at 298 K yields simple functions for high-level estimations from low levels of theory: ΔHCBS = 0.96ΔHDFT + 1.67, ΔHG4 = 0.96ΔHDFT + 1.72, ΔHDLPNO = 1.02ΔHDFT – 1.57, ΔHG4 = 0.96ΔHCBS + 2.86, ΔHDLPNO = 1.01ΔHCBS – 0.14, and ΔHDLPNO = 1.05ΔHG4 – 2.77. R2 ranges from 0.94 to 0.98 across these polynomials. Extrapolating the DPLNO barriers to the complete basis set limit tends to lower them by 0.63 kcal mol-1. EPL expressions are tailored to facilitate the development of chemical kinetic models for hemicellulose pyrolysis, as the reactant structure is the only input required, thereby contributing to the faster deployment of bioproducts at a commercial level.
Improved modeling of battery electrolytes: betting on model fitting or quantum effects?
Authors: Sarac Defne , Moreno-Martinez Diego , Doublet Marie-Liesse , Raynaud Christophe
Published: January 2025

The accurate modeling of solvent dynamics and ionic interactions is of crucial importance for the development of novel electrolytes in next-generation metal-ion batteries. This study presents a critical evaluation of the semi-classical computational approach, the adaptive Quantum Thermal Bath (adQTB) method, as a methodology for capturing the key properties of glyme-based solvents and their Ca2+-based electrolyte solutions. Simulations reveal that the adQTB method is particularly effective in accurately reproducing vibrational spectra, while offering good transferability across systems and conditions without requiring empirical parameter adjustments. In the context of electrolyte solutions, semi-classical adQTB simulations in combination with graph theory analysis indicate a distribution of the various charge-carrying clusters that is closely aligned with the conductivity measurements previously reported [Nguyen et al., Phys. Chem. Chem. Phys., 2022, 24, 21601], in sharp contrast to the empirically scaled force field. These findings emphasize the necessity of incorporating nuclear quantum effects for reliable electrolyte modeling, thereby paving the way for the advancement of post-Li battery technology.
Implementasi Metode Naïve Bayes dan Support Vector Machine (SVM) untuk Menganalisis Sentimen Pengguna Twitter terhadap Transjakarta
Authors: Ramdhania Khairunnisa Fadhilla , Hidayat Dian Fitrianto , Salkiawati Ratna
Published: January 2025

Twitter merupakan dari salah satu platform media sosial yang populer di Indonesia. Twitter menjadi salah satu media untuk mengungkapkan perasaan bagi para pengguna dan memberikan kritik atau saran terhadap suatu objek. Transjakarta merupakan salah satu transportasi umum yang memiliki jumlah penumpang harian terbanyak dibandingkan dengan transportasi umum lainnya. Berbagai pengalaman dirasakan oleh para pengguna Transjakarta. Beberapa pengguna membagikan pengalaman tersebut di Twitter. Namun tidak hanya pengalaman tetapi pendapat, kritik, dan saran juga pengguna utarakan di Twitter. Salah satu permasalahan yang terjadi pada Transjakarta yaitu beberapa halte mengalami penutupan sementara waktu. Selain itu marak terjadinya kasus asusila yang dialami oleh beberapa pengguna Transjakarta. Tujuan dari penelitian ini yaitu untuk menganalisis opini pengguna media sosial Twitter terhadap Transjakarta dengan menggunakan metode Support Vector Machine (SVM) dan  Naïve Bayes. Pada penelitian ini menggunakan lexicon based untuk pemberian label dari masing-masing kelas dan menggunakan dataset sebanyak 6736 tweet. Hasil yang didapatkan dari kelas positif berjumlah 2228 dan kelas negatif 2821. Berdasarkan Metode Support Vector Machine didapatkan akurasi 84.95%, presisi 83%, recall 83% dan f1-score 83% sedangkan Metode Naïve Bayes didapatkan akurasi 76.43%, presisi 78%, recall 68% dan f1-score 73%.
Kata kunci: Twitter; Transjakarta; Lexicon Based; Naïve Bayes; Support Vector Machine
Karakteristik Kemampuan Berpikir Kritis Siswa SMA dengan Kemampuan Kognitif Tinggi dalam Pemecahan Masalah Matematika
Authors: Safitri Ayu , Lusiana Restu , Adamura Fatriya
Published: January 2025

Penelitian ini bertujuan untuk mendeskripsikan kemampuan berpikir kritis siswa SMA dengan kemampuan kognitif tinggi dalam menyelesaikan masalah matematika. Penelitian ini menggunakan pendekatan kualitatif deskriptif. Intrumen pendukung dalam penelitian ini adalah lembar observasi, tes kemampuan berpikir kritis, pedoman wawancara, dan dokumentasi. Analisis data dalam penelitian melalui tahap reduksi, penyajian data, dan penarikan kesimpulam. Hasil penelitian menunjukkan kemampuan berpikir kritis siswa dengan kemampuan kognitif tinggi pada tiap aspek. Pada aspek interpretasi yaitu siswa membuat perumpamaan atau simbol. Pada aspek analisis, siswa menyajikan dalam bentuk poin-poin serta memberikan angka romawi atau arab di setiap poinnya. Pada aspek evaluasi, siswa menggunakan rumus alternatif substitusi dan eliminasi. Pada aspek inferensi, siswa menyajikan kesimpulan dengan menggunakan kalimatnya sendiri. Pada aspek penjelasan, siswa melihat dan membaca kembali hasil akhir yang diperoleh. Pada aspek regulasi diri, siswa membaca dan melihat kembali jawaban yang diperoleh dengan teliti dan rasa percaya diri.
Cesarean Section in a Patient with Severe Preeclampsia with Pulmonary Edema: A Case Report
Authors: Tao Yifan , Xu Guoxun , Yang Lu
Published: January 2025

Acute pulmonary edema is a leading cause of death in patients with preeclampsia. The authors reported a case of a pregnant woman at 25 weeks of gestation with severe preeclampsia complicated by pulmonary edema, who required an emergency cesarean section, posing a significant challenge to the anesthesiologist. The patient had developed Type 1 respiratory failure and needed supplemental oxygen with high-flow nasal oxygen. Due to contraindications for neuraxial anesthesia, the cesarean section was performed under general anesthesia. After induction of anesthesia, the patient’s hypoxemia worsened. Eventually, after treatment with fluid restriction, diuretics, and albumin, oxygenation improved gradually, and the procedure was performed successfully. Both the patient and the newborn had a good prognosis.
All That I Studied Gave Me a Clearer Goal” Students’ Voice: Project-Based Learning in ESP Course
Authors: Krisdianata Yoannes Yuka , Larasati Rachelina
Published: January 2025

English as the main language held an enormous role in the Ecotourism and Hospitality sectors, moreover in preparing students for the working field. This study examines the use of a project-based learning (PBL) approach in an English for Specific Purposes (ESP) course, specifically in an English for Ecotourism and Hospitality Management class for Thai students. It focuses on students’ perceptions during and after the implementation of PBL. Data were collected through interviews, revealing that participants experienced happiness and enjoyment throughout the process. Additionally, they gained greater clarity about their future goals upon completing their projects. The findings suggest that PBL in ESP not only strengthens students’ knowledge and skills but also promotes their mental well-being. The study concludes with implications and recommendations for future research on PBL and ESP.
Safety of frozen and dried forms of whole yellow mealworm (Tenebrio molitor larva) as a novel food pursuant to Regulation (EU) 2015/2283
Authors:   EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Turck Dominique , Bohn Torsten , Cámara Montaña , Castenmiller Jacqueline , De Henauw Stefaan , Hirsch‐Ernst Karen Ildico , Jos Ángeles , Maciuk Alexandre , Mangelsdorf Inge , McNulty Breige , Naska Androniki , Pentieva Kristina , Siani Alfonso , Thies Frank , Aguilera‐Gómez Margarita , Cubadda Francesco , Frenzel Thomas , Heinonen Marina , Neuhäuser‐Berthold Monika , Knutsen Helle Katrine , Poulsen Morten , Maradona Miguel Prieto , Schlatter Josef Rudolf , Siskos Alexandros , van Loveren Henk , Precup Gabriela , Ververis Ermolaos , McArdle Harry J.
Published: January 2025

Abstract
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on the safety of frozen, dried and powder forms of whole yellow mealworm (Tenebrio molitor larva) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The term yellow mealworm refers to the larval form of the insect species T. molitor. The NF consists of the frozen and dried forms of the whole yellow mealworm. The frozen form mainly consists of water, crude protein, carbohydrates and fat, whereas the dried forms consist of crude protein, fat and carbohydrates. The Panel notes that the levels of contaminants in the NF highly depend on the occurrence levels of these substances in the insect feed. The Panel notes that there are no safety concerns regarding the stability of the NF if the NF complies with the proposed specification limits during its entire shelf life. The NF has a protein content that ranges between 13 and 48 g/100 g. The Panel acknowledges that the true protein content is overestimated when using the nitrogen‐to‐protein conversion factor of 6.25 due to the presence of non‐protein nitrogen from chitin. The applicant proposed to use the NF as food ingredient in various food products. The target population proposed by the applicant is the general population. Considering the composition of the NF and the proposed conditions of use, the consumption of the NF is not nutritionally disadvantageous. The Panel notes that no safety concerns arise from the toxicological information of the NF. The Panel considers that the consumption of the NF might trigger primary sensitisation to yellow mealworm proteins and may cause allergic reactions in subjects allergic to crustaceans, dust mites and molluscs. Additionally, allergens from the feed may end up in the NF. The Panel notes that allergic reactions may occur upon consumption. The Panel concludes that the NF is safe under the proposed uses and use levels.
ENCHANTING REALMS: THE IMPACT OF J.K. ROWLING ON MODERN FANTASY LITERATURE
Authors: Parmar Prabha , Doval Ayushi Gaurav
Published: January 2025

The substantial transformational impact of J.K. Rowling on modern fantasy literature is examined in this research paper. Rowling's groundbreaking Harry Potter series drew readers of all ages to her inventive world-building, likable characters, and complex moral concerns. This paper explores how she left a lasting impact, inspired a new generation of writers and readers, and transformed the fantasy genre. It also explores the cultural phenomena of Harry Potter, including its influence on marketing, popular culture, and stage and movie adaptations. The research paper also looks at the criticisms and disputes that have surfaced over time, analyzing how these debates have affected Rowling's literary reputation and how the general public views her writing. By examining various facets, the paper draws attention to Rowling's writing's complex influence on literature and society at large.
THE INCREASING PROMINENCE OF FEMALE LEADERSHIP WITHIN THE INDIAN SPIRITUAL DOMAIN: A SOCIOLOGICAL ANALYSIS OF THE BRAHMA KUMARI SECT
Authors: Rani Neha , Malik Naveen , Joginder
Published: January 2025

The Brahma Kumari organisation embodies a significant spiritual movement marked by predominantly female leadership and extensive global outreach across 137 countries. This sect uniquely permits unmarried women to attain lifelong membership, called Brahma Kumaris (BKs). Traditionally, within Hindu culture, marriage is viewed as a crucial sacrament closely linked to vital life goals and spiritual objectives. However, in the contemporary context, the Brahma Kumari sect has gradually distanced itself from Hindu practices. Its philosophical framework suggests that marriage may hinder women's individual and spiritual advancement. Central to the Brahma Kumari belief system is the practice of Raja Yoga meditation, a transformative methodology to enhance interpersonal relationships and deepen one's connection to the natural environment. The organisation’s approach integrates spirituality, psychology, philosophy, and ecological awareness, offering a holistic perspective on well-being. Research has revealed notable correlations and divergences in life satisfaction and social adaptation among practitioners of Brahma Kumari principles. Studies indicate that the spirituality nurtured within this framework positively correlates with increased happiness and life satisfaction among adherents. This spiritual paradigm facilitates significant personal transformations and holds the potential for broader societal impact.
INTERSECTIONAL BARRIERS IN WOMEN’S ENTREPRENEURIAL ASPIRATIONS: A STUDY OF KURUKSHETRA DISTRICT IN HARYANA
Authors: Ms. Meenakshi  , Singh Kulvir , Sunil Kumar
Published: January 2025

Men and women are interconnected and essential for a harmonious society, like as two wheels of a cart, and imply that both man and woman resemble two bulls yoked in a chariot. Both genders’ contributions are vital for a balanced and prosperous society. Traditionally, patriarchal societies like India have limited women's roles to domestic duties and childcare, while men held power and influence, restricting women's access to education, employment, and social advancement. This gender division of labour and societal expectations perpetuated gender inequality and restricted women's opportunities and autonomy. Despite facing numerous obstacles, women have persistently challenged gender norms, demanded equal opportunities, and battled against discrimination. Women’s entry into business evolved from traditional kitchen activities (3P's: Pickle, Powder, Pappad) to modern fields (3E's: Energy, Electronics, Engineering) with education and time. Thus, presents study investigates the experiences, challenges, and opportunities faced by women entrepreneurs of Kurukshetra district of Haryana by employing a triangulation method. Convenience sampling was utilized to select 30 participants, comprising women entrepreneurs. The findings highlight the intersectional barriers, including socio-cultural norms, financial constraints, and lack of institutional support, that hinder women's entrepreneurial aspirations. Notably, the study reveals the resilience and adaptability of women entrepreneurs in navigating these challenges and leveraging community networks and government initiatives to foster business growth. The research contributes to the existing literature on women's entrepreneurship in rural India, emphasizing the need for targeted policy interventions, capacity-building programs, and inclusive support systems. The study's conclusions inform strategies for promoting women's economic empowerment and entrepreneurship development in Haryana, with implications for similar contexts globally.
Contextualization of The Talkin Hadith in The Book Tarjamah Bulugul Maram by Ahmad Hassan
Authors: Akbar Riko , Muhid Muhid , Nurita Andris , Muthaharoh Isnaini Lu'Lu' Atim
Published: January 2025

This research examines Ahmad Hassan's thoughts regarding Ahmad Hasan's thoughts on the Talkin hadith in the book Tarjamah Bulugh al-Maram. This research uses a qualitative approach. In data mining, library research is used by searching various written sources to obtain other supporting data. Data analysis in this research uses the content analysis method by discussing in depth the information content of the collected data in accordance with the research objectives and problems. The theory used is Syuhudi Ismail's contextualization theory. The results of this research are that Ahmad Hassan interprets what is meant by talkin as teaching, meaning teaching the deceased to answer the questions given by the Angels Munkar and Nakir in the grave regarding I'tikad. which must be believed while living in the world. For Ahmad Hassan, talkin is invalid and not justified because there is no explanation in the Quran and hadith.
Islamic Psychology-Based Educational Strategies For Student Character Development
Authors: Warsah Idi , Morganna Ruly , Warsah Berliani Aslam Alkiromah , Warsah Bizikrika Hably Hudaya
Published: January 2025

Character education is a vital component in shaping a generation with integrity and readiness to face future challenges. This study aims to identify effective models and approaches within Islamic psychology-based education strategies for student character development and to determine the success indicators of these strategies through a bibliometric review. Utilizing systematic literature reviews and bibliometric analysis, this research gathers and analyzes data from various relevant sources. The findings reveal that integrating moral and spiritual values into the curriculum significantly impacts students' development across academic, moral, spiritual, emotional, social, personal, cultural, and environmental dimensions. Effective models and approaches include fitrah-based education, tarbiyah, and akhlaq teaching, along with the involvement of parents and the community. The use of technology in character education, through Islamic psychology-based applications and platforms, also enhances student engagement and aids in the internalization of moral and spiritual values. Identified success indicators include improved academic performance, moral and ethical development, heightened spiritual awareness, engagement in social and environmental activities, and a reduction in negative behaviors. This study provides practical guidance for educators and policymakers in designing comprehensive and sustainable character education programs. Additionally, it makes a significant contribution to the academic literature by demonstrating the effectiveness of Islamic psychology-based education strategies in fostering strong and integral student character. The application of these findings is expected to assist schools and educators in cultivating a generation that is well-prepared to meet future challenges with solid character and high moral values.
The Relevance of the Concept of Hadith Jawami’ al-Kalim in the Information Era: New Strategies for Spreading the Wisdom of Islam
Authors: Zakiar Zakiar
Published: January 2025

This study examines the relevance of the Jawami’ al-Kalim hadith concept in spreading Islamic wisdom in the information age. Jawami’ al-Kalim refers to the principle of conveying Islamic teachings concisely yet comprehensively. Using literature review and content analysis methods, this research evaluates digital da'wah strategies that apply the Jawami’ al-Kalim principle. Primary and secondary sources are analyzed to identify best practices in spreading Islamic messages through digital media. The results show the effectiveness of utilizing social media, developing online educational content, and collaborating with Muslim influencers. These strategies allow Islamic da'wah to reach a wider audience, build solid online communities, and respond to contemporary issues. Although facing challenges such as misinformation, this approach opens new opportunities to strengthen religious education and positive inspiration in global society. In conclusion, applying the Jawami’ al-Kalim principle through digital technology is an important step in ensuring the relevance and effectiveness of Islamic da'wah in the information age.
Analisis Sikap Moderasi Beragama Pada Kisah Nabi Ibrahim dalam Al-Quran
Authors: Febriyarni Busra , Harmi Hendra , Yusefri
Published: January 2025

Abstrak. Tulisan ini bertujuan untuk menggambarkan sikap moderasi beragama nabi Ibrahim dalam Alquran. Ada 9 surah yang dijadikan sebagai fokus penelitian, yaitu: Al-Baqarah 124, An-Nisa 125, Al-An’am 74 – 79, Ibrahim 35 – 41, Maryam 41 – 50, Al-Anbiya’ 55 – 67, Asy-Syuara’ 83 – 87, Ash-Shaffat 99 – 102 dan Shad 45 – 48. 87  dari berbagai kitab tafsir yang muncul di Indonesia, yaitu kitab Tafsir Al-Mishbah karya Muhammad Quraish Shihab, tafsir Al-Azhar karya buya Hamka, tafsir Kementerian Agama Republik Indonesia dan tafsir Hidayatul Insan Bi Tafsiril Qur’an karya Marwan Hadidi bin Musa. Selanjutnya mengetahui nilai moderasi beragama yang terdapat pada ayat-ayat yang mengisahkan nabi Ibrahim. menggunakan library research, dengan upaya menggali data secara mendalam dari berbagai kitab tafsir Indonesia secara tematik. Untuk mengambil perbandingan keempat kitab tafsir digunakan metode muqarran (komparatif). Menyelami makna dari ayat yang dibahas menggunakan pendekatan tekstual dan kontekstual, jika diperlukan akan menggunakan teori fazlurrahman yaitu double movement. Hasil penelitian menunjukkan bahwa, nilai sikap moderasi beragama dalam kisah Nabi Ibrahim adalah: komitmen kebangsaan yang tinggi untuk mencintai tanah airnya,  nilai toleransi,  nilai dialog ketauhidan,  nilai cinta tanah air,  anti kekerasan,  komunikasi persuasif dan   dialog terbuka (musyawarah).
Proses Pemilihan Pemimpin dalam Alquran Analisis Kontekstualis Pemilu di Indonesia 2024
Authors: Hibatullah Alif , Bakar Abu
Published: January 2025

Pergantian pemimpin sering menimbulkan konflik, adanya money politic, korban jiwa, masuk daftar masalah yang dihadapi. Saat ini adanya pemaknaan baru Pasal 169 huruf q UU nomor 7 tahun 2017 Â menjadi isu politik dinasti di Indonesia. Proses pemilihan pemimpin yang seharusnya menjadi momen sakral sekaligus harapan perubahan kehidupan lebih baik bagi masyarakat, nyatanya menjadi momen pertikaian. Sebagai masyarakat muslim tentu berharap Alquran menjadi kitab jawaban persoalan zaman. Metode yang digunakan dalam penelitian ini adalah kualitatif dengan pendekatan library research. Penelitian ini menemukan ada tiga proses pemimpin dipilih. Pertama, dipilih langsung oleh Allah. Termaktub dalam surat al-Baqarah ayat 30 dan surat Sad ayat 26. Pemilihan ini merupakan hak prerogatif Allah, tidak ada yang mencampurinya serta tidak bisa digugat keputusannya. Kedua, dipilih oleh Nabi. Termaktub dalam surat al-Baqarah 246-247. Masyarakat dapat bermusyawarah untuk memberikan wewenang kepada Nabi agar menunjuk pemimpin di antara mereka. Ini merupakan metode memilih pemimpin yang cocok digunakan di Indonesia, dengan alasan minim kecurangan sekaligus mengurangi konflik masyarakat. Meski saat ini sudah tidak ada sosok Nabi sebagai penunjuk kepemimpinan, namun itu bisa diwakili oleh para wakil rakyat. Ketiga, dipilih oleh pemimpin sebelumnya. Pemimpin yang berkuasa berhak menentukan pemimpin selanjutnya, dalilnya surat Yusuf ayat 54-56. Raja Mesir yang berkuasa terkagum dengan kemampuan bahasa, takwil, mengelola harta Nabi Yusuf, dan Nabi Yusuf meminta dirinya menjadi bendahara, permintaanya dikabulkan raja. Ayat ini mengindikasikan ciri-ciri pemimpin yang berkompeten dan memikul amanat sesuai kapasitas.
The Concept of Qur'anic Communication from the Perspective of the Philosophy of Science
Authors: Kusnadi Kusnadi , Rohmah Siti , Akmal Akmal , Suryadinata M. , Arib Juhrah M. , Mokodenseho Sabil
Published: January 2025

This study aims to analyze the term al-ittishāl or al-mūashalah, specifically interpreted in Arabic as communication. The study addresses inquiries regarding the essence and existence of communication in the Qur'an from ontological, epistemological, and axiological perspectives. The focus of this study is crucial for analysis as the mainstream perception of communication in society has predominantly concentrated on aspects such as al-qaul, al-khitab, al-kalam, and the like. Employing thematic tafsir methodology, this research analyzes data primarily derived from the Qur'an, its exegesis, and hadith, while relevant books and journal articles serve as secondary sources. The research reveals that the essence of Qur'anic communication through the term al-ittishāl, stemming from the root word washala and its derivatives, recurs 12 times within the Qur'an across various chapters, all of which connote meanings of connection, seeking protection, reaching, and revelation (clarification). Meanwhile, the existence of communication in the Qur'an, from the perspective of the philosophy of science, is categorized into three aspects. Firstly, the ontological dimension of communication in the Qur'an is evident in the term yashilūna, signifying 'connected, linked, and reaching.' Secondly, the epistemological aspect of communication is depicted through its various forms within the Qur'an, encompassing verbal and non-verbal expressions, whether direct or indirect, unidirectional, or bidirectional. Thirdly, the axiological aspect of Qur'anic communication is discernible in its intended purpose or benefits, aiming for human understanding of the conveyed instructions and demonstrating the power of Allah.
Prohibition on Choosing Incompetent Leaders: Partial and Simultaneous Analysis of Abu Dzar's History in Sahih Muslim
Authors: Nugroho Nur Abdul Kholik , Damanhuri
Published: January 2025

The aim of this research is to conduct a partial and simultaneous analysis of the hadith on the prohibition of electing incompetent leaders. The scope of this research is the main hadith narrated by Abu Dzar. which was takhrij by Imam Muslim. Data relating to hadiths and the quality of each narrator is collected using documentation methods. This type of research is qualitative and data analysis uses content analysis methods. Based on partial analysis, it is found that this hadith is of authentic quality, because (1) All the narrators have the degree of thiqah . (2) Sanad hadith continues. (3) This matan hadith does not contain syadz , because there is no contradiction found with the naqli proposition, namely the Al-Qur'an and Hadith which have a higher sanad quality. (4) This hadith matan does not contain 'illat , because there is no contradiction found with the aqli proposition, namely with common sense, the senses or science. Based on simultaneous analysis; This hadith has 2 tabi ' hadiths. However, because in terms of quality the hadith already has authentic quality, the existence of this tabi'nya hadith has no effect in improving its quality. As for his martyrdom, apparently 6 hadiths of martyrdom were found, this means that the hadiths were narrated by six Companions, namely: Abu Dzar, Abu Hurairah, Auf bin Malik, Zaid bin Thabit, Abu Musa and Abdurrahman bin Samurah.
Evaluasi Pembelajaran Nilai-Nilai Keislaman di Sekolah Dasar Plus Rahmat Kediri Perspektif Logic Model
Authors: Tsani Iskandar , Sufirmansyah Sufirmansyah
Published: January 2025

This article aims to evaluate the learning of Islamic values at SD Plus Rahmat Kediri from a logic model perspective. This article is based on mixed method field research. The qualitative approach is maximized to collect data from a number of key informants through interviews, observation, and documentation. While the descriptive-quantitative approach is utilized to see how much outcome is produced. Then, the data is analyzed interactively through the stages of data collection, data reduction, data display, and conclusion drawing. This article concludes that the input of learning Islamic values at SD Plus Rahmat Kediri structurally involves the Korbid (Field Coordinator) of the School, especially the Faith and Taqwa Field, the Facilities and Infrastructure Field, the Grade Level Coordinator, Classroom Teachers and Homeroom Teachers, the Ummi Learning Session Coordinator, and the ustadz/ustadzah from the Ummi Foundation. Culturally, the school climate at SD Plus Rahmat Kediri is very good, as manifested in the academic field, community aspect, security aspect, and institutional environment. The morning muroja'ah activity has an impact on the emergence of the Islamic values of ta'addub, qudwah, and i'tidal. BTQ tutoring in the Ummi method produces the Islamic values of tathawwur wa ibtikar, qudwah, and i'tidal. The dhuha and dhuhur prayer congregation activities bring out the Islamic values of ta'addub, qudwah, and shura. The activities of clean friday and blessed friday bring out the Islamic values of musawah, ta'addub, tathawwur wa ibtikar, and tasamuh.
Patient Perspectives: The Effects of Contemporary Phosphorus Management on Quality of Life
Authors: Levy Michael , Alex Berrios Alex x
Published: January 2025

Effective regulation of phosphate levels is essential for managing the health of the nearly 600,000 dialysis patients in the United States, over 43% of whom exceed the recommended serum phosphate target of 5.5 mg/dL. Current phosphate binders present significant challenges, including large pills that are hard to swallow, pills that require thorough chewing, which may be difficult for patients with impaired dentition, frequent dosing, gastrointestinal adverse effects, and the need to take them while in public, which can lead to non-adherence and reduced social eating. Coupled with stringent dietary restrictions, confusion over administration timing, and high medication cost, these factors severely compromise patients’ quality of life. Addressing these barriers requires a comprehensive strategy: clinicians must recognize the difficulties faced by patients, bridge knowledge gaps regarding dietary phosphorus, and explore novel therapies that reduce pill size and burden without sacrificing efficacy. By mitigating these challenges, healthcare providers can enhance treatment experiences, strengthen patient-clinician relationships, and ultimately improve overall quality of life for dialysis patients. With a focus on patients’ perspectives, this review highlights the critical need for patient-centered approaches in phosphate management to ensure better clinical outcomes and patient satisfaction.
OPTIMIZATION OF THE CONDITIONS OF ULTRASONIC EXTRACTION OF POLYPHENOLIC COMPOUNDS FROM THE INFLORESCENCES OF KOENIGIA WEYRICHII (F. SCHMIDT) T.M. SCHUST. ET REVEAL
Authors: Korovkina A.V. , Koigerova A.A. , Tsvetov N.S. , Mizina P.G.
Published: January 2025

Introduction. Inflorescences of Koenigia weyrichii (F. Schmidt) T.M. Schust. et Reveal contains a large amount of flavonoids. However, at present, the most optimal conditions for their extraction by water-ethanol mixtures have not been obtained, and the effect of ultrasound on the extraction pro-cess has not been fully studied. The aim of the study was to optimize the conditions of ultrasonic water-ethanol extraction of secondary metabolites from the inflorescences of K. weyrichii. Material and methods. Optimal extraction conditions have been established using the Box-Behnken algorithm. The total content of polyphenols was determined using the Folin-Ciocalteu method, and flavonoids were determined using a complexation reaction with aluminum chloride. The total antioxi-dant activity was assessed using the phosphomolybdate method. The content of polyphenolic acids was determined by HPLC. The ability of the extract obtained under optimal conditions to inhibit free radicals was determined by DPPH and ABTS methods. Results. The highest yield of the target substances is achieved in 60 minutes of extraction in 50% aqueous ethanol at a temperature of 50 ° C, and mixing plant material with a particle size of 0.1 mm with an solvent in a ratio of 1:10 (mass to volume. It has been shown that ultrasound exposure reduces the yield of target substances. Conclusions. The results of the work are the scientific basis for the development of methods of phytochemical analysis and technologies for the pro-duction of pharmaceuticals based on the studied plant.
EXPERIMENTAL SEARCH AN UNDERLYING BASIS OF PRINCIPLES FOR MICROBIOLOGICAL QUANTITATIVE ASSESSMENT OF PRESERVATIVE SOLUTIONS
Authors: Panin V.P. , Emer N.R.
Published: January 2025

Introduction. Microbiological control of preservative solutions and assessment of the state of anatomical preparations are topical issues, the solution of which requires adaptation of methods for quantitative determination of the level of microbial contamination to the special conditions of equilibrium systems containing biological preparations. The aim of the study is screening, experimental testing and adaptation of microbiological methods for quantitative assessment of the level of microbial contamination for monitoring the microbiological purity of preservative solutions using the Melnikov–Razvedenkov solution as an example. Material and methods. The object of the study was the Melnikov–Razvedenkov preservative solution modified by the Scientific Research Center for Biomedical Technologies of the All-Russian Scientific Research Institute of Medicinal and Aromatic Plants. The study used methods for quantitative assessment of the level of microbial contamination on agar nutrient media. Results. As a result of screening, experimental testing and comparative analysis of methods for quantitative assessment of the level of microbial contamination, the most promising methodological approaches were identified and adapted for microbiological monitoring of modified Melnikov-Razvedenkov solution. Conclusions. The microbiological study of the modified Melnikov-Razvedenkov preservative solution showed the feasibility of using the membrane vacuum filtration method with membrane filters made of a mixture of cellulose acetate and nitrate with a nominal pore diameter of 0.45 μm. For sterilization of the test solution, the use of a vacuum filtration through membrane filters with a nominal pore diameter of 0.22 μm is promising.