bluuebunny/crossref_metadata_2025 huggingface dataset:
Fine-grained Fiber Concrete on Mechanoactivated Portlandcement
Authors: Anatolii Vorokhaiev , Ivan Barabash , Liubov Ksonshkevych , Zeljko Kos , Iryna Grynyova
Published: September 2021

This article is devoted to the study of the mechanical properties of fine-grained concrete used for flooring in industrial and civil buildings. Characterized by the well-known advantages (unlimited raw material base, manufacturability, high homogeneity), fine-grained concrete requires an increased consumption of cement to achieve the necessary mechanical characteristics - compressive strength, abrasion, impact resistance. An alternative to the known technological method is proposed an intensive separate technology (IST) for preparing fine-grained concrete mixtures using a high-speed mixer-activator in the presence of hydrophobized basalt fiber and a polycarboxylate superplasticizer Relaxol-Super PC. The use of IST leads to an increase in the strength of fine-grained concrete in compression by 1.9 times, impact resistance by a factor of 2, and a decrease in abrasion by 40... 50% in comparison with the control. The relevance of using the technology of monolithic floors for industrial and civil construction is due to a wide range of varieties of Portland cement, the grain composition of aggregates, as well as the simplicity of the technology for preparing a fine-grained concrete mixture.
Frost resistance of cement-sand and concrete beams during unilateral freezing
Authors: Nikolaevich Nepomyach Alexander , Nikolaevich Vyrovoy Valeriy , Aleksaedrovich Chistyakov Artem
Published: September 2021

The work investigates changes in the beam structure under the action of local freezing, which leads to a change of the mechanical properties of the material and, consequently, of the beam structure. Two types of beam samples were used: from cement-sand mortar and from concrete. The work investigates the change in the development of deformations depending on the conditions of freezing of samples. The second accelerated method for assessing frost resistance was chosen according to DSTU B В.2.7-47-96. An accelerated method was chosen for assessing frost resistance at the temperature of -20 ±2 C°. After every five freeze-thaw cycles, the following changes were monitored: mass, water absorption, ultrasound transmission rate, damage coefficient, tensile bending strength, splitting strength, compressive strength, carbonization depth. The results showed that both in concrete and in mortar samples, the compressive strength after freezing was lower by 8% and 15% accordingly. The experimental results obtained confirm the assumptions made that the frost resistance of the material depends on the conditions of exposure of negative temperatures on products and structures and it can be used in a wider range of construction which will push regional development.
Innovative methods of non-destructive evaluation of log quality
Authors: Ondrejka Vojtěch , Gergeľ Tomáš , Bucha Tomáš , Pástor Michal
Published: September 2021

For the sustainability of an important renewable resource, such as wood, it is important to significantly increase the efficiency of its processing. A large part of this raw material ends up in the wood processing industry, where it is used for the production of pulp, paper, construction and furniture timber, floors and others. Therefore, it is very important to gain the knowledge needed for optimal valuation of raw wood material, through quality detection and classification into quality classes. There are many defectoscopic methods working on different physical principles. The most familiar of these methods are semi-destructive and non-destructive, as they do not cause damage to the tree or wood during assessment. The aim of this article is to describe, assess and compare known semi-destructive and non-destructive methods for the assessment of wood properties. This article describes basic visual inspection, basic semi-destructive methods (Pilodyn, Resistograph) and advanced semi-destructive methods (SilviScan®, DiscBot®) as well. Non-destructive methods use mostly acoustic wave motion (acoustic, ultrasonic), high-frequency waves (using georadar, microwave) and methods based on visual evaluation (image, laser). At last, there are X–ray methods with the latest technology using three-dimensional (3D) computed tomography (CT). The implementation of modern non-destructive methods is of great importance for the application of principles of Industry 4.0, where these methods provide collecting of data on the material properties, in its entire production flow of log processing.
RISK MANAGEMENT AND BANKING PERFORMANCE WITH CORPORATE GOVERNANCE AS MODERATING VARIABLE
Authors: Hikmawati Santi , Sutrisno Sutrisno
Published: September 2021

This research aims to analyze the effect of risk management on bank financial performance with corporate governance as a moderating variable. The independent variables used in this research are risk management, consist of credit risk (NPL), liquidity risk (LDR), and operating risk (OEIR). The dependent variable used is financial performance (ROA). Meanwhile, corporate governance as a moderating variable and firm size as a control variable. The regression model used are multiple linear regression analysis and moderated regression analysis. The sample was selected through purposive sampling method and 43 banks were selected as research sample. The result of this research showed that NPL and OEIR have a negative and significant impact on financial performance. Meanwhile, LDR has not significant effect on financial performance. Corporate governance was able to moderate the relationship between NPL and OEIR on financial performance, but unable to moderate the relationship between LDR on financial performance.
Apollo Flights and the Hazards of Radiation
Authors:   Paleo Faliro, Salerian Alen J
Published: September 2021

This correspondence inspired by recent NASA plans for two astronauts to spend 6.5 days on the moon-reviews the radiation effects upon the Apollo astronauts who traveled to the moon and back from 1969 to 1972.
WISH-Type Hip Brace for Patients with Osteoarthritis of the Hip
Authors:   Takasaki University Of Health And Welfare, Watanabe Hideomi
Published: September 2021

We developed a user-friendly WISH-type hip brace that reinforces the hip joint by preventing up- and outward movement of the femoral head.
The Stability of Mastery Motivation and its Relationship with Motor Competence Influenced by Gender in Preschoolers
Authors:   Asia University, Wang Pei-Jung
Published: September 2021

Mastery motivation (intrinsic drives to explore and master one’s environment) is a key aspect of development in children.
Neurological and Neuropathological Findings in Dengue: A Review
Authors:   Fuldade De Medicina Da Universidade De São Paulo, Frassetto Fernando Pereira
Published: September 2021

Dengue is an infectious disease endemic in large regions of the world, caused by the dengue virus, subtypes 1 to 4, transmitted by mosquitoes of the Aedes genus.
Mechanical and Thermodynamic Properties of Mesenchymal Stem Cells Differentiated into Myofibroblasts: A Commentary on the Article “Statistical Mechanics of Non-Muscle Myosin IIA in Human Bone Marrow-Derived Mesenchymal Stromal Cells Seeded in a Collagen Scaffold: A Thermodynamic Near-Equilibrium Linear System Modified by the Tripeptide Arg-Gly-Asp (RGD)”
Authors:   Centre De Recherche Clinique, Grand Hôpital De L’Est Francilien, 77104 Meaux, France, Lecarpentier Yves
Published: September 2021

Mesenchymal Stem Cells (MSCs) are multipotent stromal cells found in bone marrow and have the capacity to differentiate into myofibroblast. In contractile myofibroblasts, the molecular motor is the non-muscle myosin (NMIIA) which differs from the muscle myosin by its ultra-slow kinetics. The differentiation of MSCs into myofibroblasts is promoted by the “Transforming Growth Factor” (TGF-b) which represents a potentially target against tissue fibrosis and cancer.
Biochemical and Biomechanical Myogenic Differentiation of Adipose-Derived Stem Cells for Tissue Engineering Applications
Authors:   Human Health Therapeutics, National Research Council Of Canada, 1200 Montreal Road, Ottawa, ON K1A0R6, Canada, Yogi Alvaro
Published: September 2021

Tissue engineering has shown great promise in generating vascular grafts with properties similar to that of native blood vessels. Vascular Smooth Muscle Cells (VSMC) are the main component of the vasculature tunica media. Recreation of this layer represents a major challenge in tissue engineering due to difficulties in harvesting and culturing autologous VSMC. The use of stem cells and their inherent ability to differentiate into diverse cell types, including vascular lineages, have been proposed
CHARACTERISTICS OF SOME OBSTETRIC AND GYNECOLOGICAL FEATURES IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME AND CONCOMITANT THYROID GLAND PATHOLOGY
Authors:   Azerbaijan State Advanced Training Institute for Doctors named after A. Aliyev, Baku, Azerbaijan, MEKHDIEVA L.A.
Published: September 2021

To study certain obstetric and gynecological characteristics in patients with polycystic ovary syndrome (PCOS) and hypothyroidism.
THE USE OF ANATOMIC TABLE FOR STUDYING THE VARIANT ANATOMY OF THE SUBCLAVIAN AND AXILLARY ARTERIES
Authors:   Department of Fundamental Medicine and Biochemistry, Pskov State University, Pskov, Russian Federation, MURASHOV O.V.
Published: September 2021

To study of the variant anatomy of the subclavian and axillary arteries and compare the obtained data with the classical anatomy of Russian and foreign anatomical schools.
LAMELLAR KERATOPLASTY WITH THE CROSS-LINKING APPLICATION IN TREATMENT OF KERATOCONUS
Authors:   Department of Ophthalmology, Medical Faculty, Kyrgyz-Russian Slavic University, Bishkek, Kyrgyz Republic, MEDVEDEV M.A. , BEBEZOV B.KH. ,   Department of Hospital Surgery, Medical Faculty, Kyrgyz-Russian Slavic University, Bishkek, Kyrgyz Republic, TURGUNBAEV N.A. ,   Department of Ophthalmology, Medical Faculty, Kyrgyz-Russian Slavic University, Bishkek, Kyrgyz Republic, OSTROVERKHOV A.I. ,   Department of Ophthalmology, Medical Faculty, Kyrgyz-Russian Slavic University, Bishkek, Kyrgyz Republic
Published: September 2021

To study the effectiveness and safety of using a combination of lamellar keratoplasty and cross-linking in the treatment of keratoconus.
FEATURES OF TREATMENT TACTICS FOR PATIENTS WITH «HIGH RISK» ACUTE OBSTRUCTIVE CHOLECYSTITIS
Authors:   Department of General Surgery № 2, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, ABDULLOZODA D.A. , GULOMOV L.A. ,   Department of General Surgery № 2, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, SAFARZODA A.M. ,   Department of General Surgery № 1, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
Published: September 2021

To improve the results of surgical treatment of patients with high operational and anesthetic risk, the suffering of acute obstructive cholecystitis (AOC), by improving two-stage tactics.
ACTUAL PROBLEMS OF VARICOCELE IN ADOLESCENTS
Authors:   Department of Surgical Diseases № 2, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, ARTYKOV K.P. , KHUSEYNZODA D. ,   Republican Scientific Center for Cardiovascular Surgery, Dushanbe, Republic of Tajikistan, YULDOSHOV M. A. ,   Department of Surgical Diseases № 2, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, KHVAN I.N. ,   Department of Surgery, Tajik National University, Dushanbe, Republic of Tajikistan
Published: September 2021

In recent years, cases of detection of varicocele in adolescent age have increased and the using methods of treatment for this population remain controversial. The literature analysis revealed a variety of approaches to the therapy of the pathology: there are supporters of both surgical treatment and conservative therapy and dynamic surveillance. It is known that about 20-40% of adolescents with varicocele are potentially infertile, and they need early surgery for indications such as testicle hypotrophy, pathospermia. However, the existing methods of treatment of varicocele are accompanied by the recurrence, with hydrocele development, and progressive testicle injuries. Furthermore, the results of applicable methods of treatment are limited, characterized by low evidence, lack of randomized controlled researches.
SYSTEMATIC REVIEW WITH COMPARATIVE ANALYSIS OF RECOMMENDATIONS FOR THE DIAGNOSIS OF NONALCOHOLIC FATTY LIVER DISEASE
Authors:   Department of Internal Medicine № 1 of the specialties «Pediatrics» and «Dentistry», Kyrgyz-Russian Slavic University named after B.N. Yeltsin, Bishkek, Kyrgyz Republic, TOKTOGULOVA N.A.
Published: September 2021

A review of the available literature has shown that the current epidemic of nonalcoholic fatty liver disease (NAFLD) is closely related with the widespread prevalence of metabolic risk factors worldwide, such as obesity, type 2 diabetes, and dyslipidemia. In parallel with the increasing availability of effective antiviral drugs, NAFLD is rapidly becoming the most common cause of chronic liver disease in Western countries, and a similar trend is expected in Eastern countries in the coming years. This epidemic and its aftermath have prompted experts from around the world to identify effective strategies for the diagnosis, management and treatment of NAFLD. Various scientific associations from America, Europe and the Asia-Pacific region have offered recommendations based on the most recent data on NAFLD. These recommendations are consistent with the key elements of NAFLD management, but at the same time, there are significant differences in some critical points. We have identified clinical guidelines from 8 different scientific societies with a worldwide reputation, and tried to conduct a systematic and comparative analysis of the presented protocols. Differences were noted in: definition of NAFLD, screening for NAFLD in high-risk patients, a non-invasive test proposed to diagnose NAFLD and identify NAFLD patients with severe fibrosis, follow-up protocols, and finally, treatment strategy
Reserves for improving perinatal indicators by analyzing the outcomes of preterm labor
Authors:   Tajik Scientific Research Institute of Obstetrics, Gynecology and Perinatology, Dushanbe, Republic of Tajikistan, ISHAN-KHODZHAEVA F.R. , KAMILOVA M.YA.
Published: September 2021

Outline ways to improve perinatal outcomes as a result of analysis of the structure and methods of delivery in preterm labor (PL).
EPIDEMIOLOGY, RISK FACTORS, DIAGNOSTICS AND PREVENTION OF DEEP VENOUS THROMBOSIS IN FRACTURES OF LONG BONES OF THE LOWER EXTREMITIES
Authors:   Republican Scientific Center for Cardiovascular Surgery, Dushanbe, Republic of Tajikistan, NEMATZODA O. , KURBANOV S.KH. ,   Department of Traumatology, Orthopedics and Military Surgery, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, MAKHMUDOV D.SH. ,   Department of Traumatology, Orthopedics and Military Surgery, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan
Published: September 2021

A literature review presents a data concerning the incidence and risk factors for development of venous thromboembolic complications (VTEC), as well as their diagnosis and prevention in long bones fractures of the lower extremities (LBFLE). Literature data show that, despite the widespread implementation of preventive measures in case of LBFLE, it is not always possible to completely avoid VTEC. The main risk factors for their development are the injuries’ severity, the location and nature of the extremity bone fracture, the duration of immobilization, the amount of surgery performed for bone fragments stabilization, as well as age and the presence of concomitant diseases. In the diagnosis of thrombotic process, laboratory and radiation research methods play an essential role, and according to data they has varying degrees of sensitivity and specificity. However, to date, none of them has absolute diagnostic accuracy. Complex thrombosis prophylaxis significantly reduces the risk of VTEC development, however, the choice of the type and dosage of anticoagulants, as well as the duration of their use, remain controversial, and some authors recommend different approaches in this issue. In addition, the diagnostic criteria and therapeutic tactics for embologenic floating thrombi remain open for discussion. In this regard, the conduct of large randomized scientific studies aimed at early diagnosis, prevention and treatment of VTEC using modern diagnostic tests and new generation anticoagulants is relevant and allows to minimize the risk of disability and death.
Reevaluating incarcerated juvenile education in the wake of COVID-19: Why the juvenile system should take advantage of the online learning wave
Authors:   Maurer School of Law, Indiana University, Bloomington, IN, USA, Hutwagner Catherine
Published: September 2021

Incarcerated juveniles have the greatest need for education and potential for improvement, yet they are one of the most underserved populations in terms of public education. Juveniles in detention centers receive a lower quality education when compared to public education systems–courses exclusively based on worksheets, single-room style teaching methods, a shortage of textbooks, and underqualified teachers. They also struggle to earn and transfer credits. In addition, solitary confinement often denies access to education, adding further disadvantages. Currently, juveniles have a low reenrollment rate in the public education system after their release. This paper presents a solution for the future of juvenile education, using the national response to COVID-19 of moving education online as a blueprint, combined with social science research, to provide small amendments to promote an effective learning environment.
An evaluation study of Anganwadis under ICDS in India
Authors:   Indian Institute of Public Administration, New Delhi, India, Panda Pradeep Kumar
Published: September 2021

Integrated Child Development Services (ICDS) scheme has expanded tremendously over the 30 years of its operation to cover almost all the development blocks in the country. It offers a wide range of health, nutrition and education related services to children, women and adolescent girls. The study wish to find out the impact and efficacy of the ICDS scheme. The study was conducted from April 2019 to December 2019. The study was conducted on purposive random sampling basis covering 19 States/UTs. 510 AWCs were selected and total 15300 children were covered. One of the important findings of the study is that the children in the Normal grade are found to be 77.4% of the total sample size which means that in spite of a lot of bottlenecks, the malnutrition has been reduced among the children of 0 to 5 years of age. As envisages from the field study, people are well aware of the ICDS scheme and are sending their children to AWCs. However, the children from remote areas are not able to avail these facilities. The opening of public nursery school in urban and rural areas poses a great threat to the enrollment of children in AWCs nowadays unless the infrastructural and other facilities of AWCs are upgraded. The working conditions and remuneration of AWC workers needs to be looked at sympathetically. The findings of the study are expected to help policymakers and programme implementing bodies to take appropriate corrective measures to make the ICDS more effective and thereby bringing down the malnutrition in children to zero level.
Experiencias inaudibles del horror. Entre la anticipación en Levinas y la rememoración en Levi
Authors: Scherbosky Federica
Published: September 2021

¿Por qué volver a pensar Auschwitz? ¿Qué sentido tendría si ya se ha abordado innumerables veces? Por un intento de comprensión del horror que no descansa y en ese marco destacamos los aportes de Emmanuel Levinas y de Primo Levi. El primero en Algunas reflexiones sobre la filosofía del hitlerismo (1934) anuncia y denuncia la estructura de exterminio que esta implicaba. El segundo en Si esto es un hombre escrito en 1946 y publicado en 1947, bajo el imperativo del testimonio, sostiene que sobrevivir tuvo sentido para poder contar lo sucedido. Ambos textos tuvieron dificultades para ser oídos y consideramos que esto se debe a la premura de sus denuncias. Esas experiencias inaudibles lo fueron tanto por el objeto del relato –un horror desconocido hasta entonces- como por un régimen de sensibilidad que aún no podía abrirse a semejante escucha.
Nietzsche y la filosofía experimental. Estudios y perspectivas
Authors: Choque Osman
Published: September 2021

La expresión filosofía experimental ha cobrado un vivo interés en las recientes investigaciones sobre Nietzsche, como lo deja ver el número creciente de intérpretes. Esta reflexión ocupó un lugar pequeño en las discusiones a finales del siglo XX; situación que cambió rotundamente a comienzos de nuestro siglo. Para comprender las cuestiones que giran en torno a dicha filosofía es necesario considerar sus límites y alcances y, ante todo, el espacio que ocupa en la obra del pensador alemán. Por medio de un acercamiento filológico, el desarrollo de los últimos trabajos y los diferentes usos del concepto podremos resaltar los matices de este proyecto prometedor. Este trabajo pretende acercar al lector, por la novedad en lengua hispana, a esta discusión que va atrayendo la mirada de los interesados por el filósofo de Röcken.
The World as a Quantum Information Processor
Authors: Maldonado Carlos Eduardo
Published: September 2021

It is impossible to fully grasp reality and the universe without a sound understanding of quantum science, i.e. theory. The aim of this paper is twofold, namely first presenting what quantum information processing consists of, and then consequently discussing the implications of quantum science to the understanding of reality. I shall claim that the world is fully quantum, and the classical world is but a limit case of the quantum world. The crux of the argument is that quantum information can be taken as a living phenomenon. Quantum information processing (QIP) has been mainly the subject of computational approaches. Here we take it as the way in which information allows for a non-dualistic explanation of the world. In this sense, quantum information processing consists in understanding how entanglement stands as the ground for a coherent reality yet highly dynamical, vibrant and vivid. Information, I argue, is a living phenomenon that creates itself out of nothing. Quantum information is a relational view of entities, systems, phenomena, and events (Auletta, 2005).
ОРГАНІЗАЦІЯ МОНІТОРИНГУ ТА ПРОГНОЗУВАННЯ РОЗВИТКУ РЕГІОНАЛЬНИХ СИСТЕМ ВИЩОЇ ОСВІТИ
Authors: Lomonosova Oksana
Published: September 2021

The need for appropriate providing the leading stakeholders of higher education with objective information about the local universities' status and development is justified, which is important for making managerial decisions. It requires continuous monitoring and forecasting of the changes at the regional educational services markets in higher education. A complex of studies should include analysis, assessment, and forecasting of processes in higher education of the region, as well as in the labor market. It is shown that effective monitoring is possible only under the condition of close interaction of local higher education institutions, state authorities, and local self-government. The role of the latter is to determine the directions of the regional labor market development and to forecast its changes. On the example of the Kherson region, it is shown that a research and development monitoring center, established by the state authorities, may be a possible organizational form that allows performing the necessary research.
Evaluation of Signs of Skin Aging in Patients with Metabolic Syndrome after Substitution Therapy with Antioxidants. Summary of the Doctoral Thesis
Authors:   ,   Rīga Stradiņš University, Janovska Jana
Published: September 2021

Skin aging is a complex biological phenomenon consisting of two overlapping components: internal (true aging) and external. OS, which is believed to play a central pathogenic role in the development of MetS, is a state of prooxidant / antioxidant imbalance in which the net amount of Reactive Oxygen Species (ROS) exceeds the body's antioxidant defenses. Excess ROS can cause lipid, protein oxidation, and oxidative damage to DNA. MetS is a syndrome, of which main symptoms are obesity, insulin resistance (IR), dyslipidemia and hypertension or high blood pressure. About a third of the adult population in developing countries is currently classified as having MetS according to various criteria (Moore and Chaudhary, and Akinyemiju, 2017). The use of AO has been observed to reduce the OS and inflammatory response involved in the development of MetS (Soory, 2012). The effects of selenium on the expression and secretion of inflammatory and OS biomarkers have been studied in vitro and in vivo in experimental MetS models as well as in humans. There are many studies in the literature on various parameters influenced by blood selenium (Se) levels, such as C-reactive protein, interleukin-6, tumor necrosis factor-alpha, interleukin-1 beta, and retinol-binding protein (Rayman, 2000; Alissa and Bahijri, and Ferns, 2003). Intake of Se and other AOs is associated with lower C-reactive protein (CRP) in women, indicating a possible anti-inflammatory effect of dietary AO. The above is also relevant in Latvia but has not been studied. There are patients with diabetes, light skin phototype, MetS, cardiovascular diseases in Latvia, but visual changes do not give a complete picture of the aging processes in the skin. Aim of the study. To study the signs of skin photoaging and evaluate the effectiveness of AO therapy in patients with MetS in the Latvian population. Tasks of the study: 1. Evaluate MetS symptoms and skin parameters in MetS patients and control groups. 2. Identify and describe the signs of skin aging in the group of MetS patients (visually, as well as using dermatoscopic and histological examination). 3. Evaluate the skin changes after organic selenium substitution. 4. Evaluate the interrelationships between MetS symptoms, OS parameters and skin changes in MetS patients and control groups. Hypothesis: AO substitution improves skin aging parameters in MetS patients.
Ahorro del costo de hospitalización con técnica WALANT en la resolución quirúrgica del síndrome del túnel carpiano y tenosinovitis de De Quervain. Evaluación de costos en un hospital privado de Quito, Ecuador
Authors: Cayón Cayón Fidel , Alarcón Serrano Juan Pablo
Published: September 2021

Introducción. El interés en los beneficios del uso de técnicas anestésicas regionales en ortopedia y traumatología ha aumentado en los últimos años ya que estas permiten realizar varios procesos quirúrgicos en la mano y en la muñeca de forma segura y ambulatoria, y sin los efectos secundarios de la anestesia general ni la necesidad de monitorización en la unidad de cuidados posanestésicos, disminuyendo así el uso de los recursos hospitalarios.

Objetivo. Estimar el valor promedio de ahorro en los gastos en procedimientos quirúrgicos de la mano en pacientes atendidos con la técnica WALANT comparada con anestesia general.

Materiales y métodos. Se compararon los costos que ocasionaron 14 pacientes operados mediante la técnica WALANT versus los ocasionados por 13 pacientes operados bajo anestesia general.

Resultados. Las cirugías realizadas mediante técnica WALANT implicaron un menorcosto en comparación a las ejecutadas bajo anestesia general.

Conclusiones. La cirugía del síndrome del túnel carpiano y tenosinovitis de De Quervain bajo anestesia local sin torniquete y con el paciente despierto (técnica WALANT) permite disminuir los costos en un promedio de US$391,80 (54.36%).
Using smartphone-based accelerometers to gauge postoperative outcomes in patients with NPH: Implications for ambulatory monitoring
Authors: Sprau Annelise Claire , Basil Gregory W. , Eliahu Karen , Vallejo Frederic A. , Luther Evan M. , Yoon Jang W. , Wang Michael Y. , Komotar Ricardo J.
Published: September 2021

Background:

The surgical treatment of normal pressure hydrocephalus (NPH) with shunting remains controversial due to the difficulty in distinguishing such pathology from other neurological conditions that can present similarly. Thus, patients with suspected NPH should be carefully selected for surgical intervention. Historically, clinical improvement has been measured by the use of functional grades, alleviation of symptoms, and/or patient/family-member reported surveys. Such outcome analysis can be subjective, and there is difficulty in quantifying cognition. Thus, a push for a more quantifiable and objective investigation is warranted, especially for patients with idiopathic NPH (INPH), for which the final diagnosis is confirmed with postoperative clinical improvement. We aimed to use Apple Health (Apple Inc., Cupertino, CA) data to approximate physical activity levels before and after shunt placement for NPH as an objective outcome measurement. The patients were contacted and verbally consented to export Apple Health activity data. The patient’s physical activity data were then analyzed. A chart review from the patient’s EMR was performed to understand and better correlate recovery.

Case Description:

Our first patient had short-term improvements in activity levels when compared to his preoperative activity. The patient’s activity level subsequently decreased at 6 months and onward. This decline was simultaneous to new-onset lumbar pain. Our second patient experienced sustained improvements in activity levels for 12 months after his operation. His mobility data were in congruence with his subjectively reported improvement in clinical symptoms. He subsequently experienced a late-decline that began at 48-months. His late deterioration was likely confounded by exogenous factors such as further neurodegenerative diseases coupled with old age.

Conclusion:

The use of objective activity data offers a number of key benefits in the analysis of shunted patients with NPH/INPH. In this distinctive patient population, detailed functional outcome analysis is imperative because the long-term prognosis can be affected by comorbid factors or life expectancy. The benefits from using smartphone-based accelerometers for objective outcome metrics are abundant and such an application can serve as a clinical aid to better optimize surgical and recovery care.
A rare case of ruptured intracranial aneurysm arising from the retro-mastoid branch of the occipital artery
Authors: Aljuboori Zaid , McGrath Margaret , Jadhav Rahul , Ghodke Basavaraj , Sekhar Laligam
Published: September 2021

Background:

Aneurysms of the occipital artery (OA) are rare, with few cases published in the literature. The pathophysiology is unknown, and the presentation is variable. We present a case of a ruptured intracranial aneurysm arising from a branch of the OA.

Case Description:

A 36-year-old male with a history of ankylosing spondylitis presented with altered mental status after an assaulted. On examination, he was intubated, with a Glasgow coma scale of 9, and imaging of the head and neck revealed a subdural hematoma of the posterior fossa and the cervical spine. The patient underwent suboccipital craniectomy and C1-5 laminectomy with the evacuation of the subdural hematoma. Postoperative cerebral angiography showed an intracranial aneurysm arising from the retromastoid branch of the OA on the left side. Furthermore, the parent vessel of the aneurysm supplied the left lower half of the cerebellar hemisphere. The aneurysm and the parent vessel were embolized using platinum coils. The patient tolerated the procedure well, and magnetic resonance imaging of the brain showed a minor left-sided cerebellar infarct, which was asymptomatic. The patient was discharged home with a modified Rankin scale of 2. There were no outpatient follow-up data available because the patient lost to follow-up.

Conclusion:

Intracranial OA aneurysms are extremely rare with no clear consensus concerning the management of these aneurysms. They can be treated using endovascular and or open surgical techniques depending on the aneurysm characteristics, patient condition, rupture status, and others.
Molecular Docking and ADME Study of Quinoline and Chalcone based Derivatives for Anti-Cancer Activity
Authors: Kuldeep Patel  , Richa Dubey  , Shaifali Soni  , Jagdish Chandra Rathi  , Neerupma Dhiman
Published: September 2021

Cancer is a big issue that affects people all over the world. It develops as a result of uncontrolled cell growth. The interaction between developed ligands and thymine phosphorylation was investigated in this study, which was computationally optimized. The aim of this study was to examine the anticancerous activity of designed ligands in thymine phosphorylation (PDB ID: 1UOU) in order to minimize the cost and time required to develop a novel anticancer drug with minimal side effects. All the designed ligands showed mild to excellent binding with proteins. Most of the ligands exhibited better interaction compared to reference compound Tamoxifen with pdb files. Some of the designed ligands among (1-7) in qunoline derivatives and (1-5) in Chalcone derivatives showed excellent docking scores with PDB file (1UOU) of thymine phosphorylation. All the designed ligands and Zinc databases were docked with 1UOU PDB files of protein, and it was found that out of twenty-five designed ligands in Qunoline series, ligand 25 showed the best binding (docking score −8.268) with 1UOU PDB of protein thymine phosphorylation. And that out of ten designed ligands in Chalcone series, ligand K1 showed the best binding (docking score −9.433) with 1UOU PDB of protein thymine phosphorylation. Docked ligand cavity of ligand ku 25 in qunoline series and K 9 in Chalcone series showed important hydrophobic/non-polar residues such as Ile199, Ile316, Trp119, Phe168, Ile198, Cys172, Tyr188, Tyr398, Tyr435, Phe343, Tyr60, Leu328, Leu171, and showed pi-pi interaction with Tyr326. Further wet laboratory studies are continued in our laboratory to confirm and find out the efficiency and activity of target compounds.
¿En qué sentido puede hablarse de literatura como otra forma de conocimiento complejo? Elementos para un acercamiento entre ciencia y literatura
Authors: Baldoví Giraldo Jose María
Published: September 2021

No solamente es necesario el diálogo entre las ciencias y las artes, especialmente la literatura. Es preciso, asimismo, concebir a la literatura como una forma de pensamiento complejo capaz de generar conocimiento. En ese sentido, una expresión como la novela constituye en sí misma un sistema complejo que bien puede compaginarse con las cualidades de las ciencias. La metáfora literaria es múltiple en sus connotaciones y hace universales las experiencias particulares; la expresión científica es unívoca y da razón del mundo exterior. Los intercambios entre ambos modos de entender el mundo pueden ampliar la visión compleja de la vida.
TRADE AND ENVIRONMENTAL RISKS OF MODERN MODERNIZING ECONOMIES: INTERRE-LATION AND DISPROPORTIONS
Authors:   MGIMO University, Sarkisyan Jacqueline M.
Published: September 2021

The article presents the results of the research about the directions of development of countries with a modernized economy, including the advantages and limitations for the development of raw material exports. The possibilities of preserving the raw material strategy for the development and restructuring of industry and agriculture in developing countries, taking into account the projected commodity super — cycle, are identified. At the same time, the interrelationships of trade and competition risks in the context of increasing international exchange and increasing the likelihood of environmental risks, including the spread of the use of alternative energy, are determined.
PERSONNEL POLICY IN THE FOREST INDUSTRY OF THE KRASNOYARSK TERRITORY: РROBLEMS AND SOLUTIONS IN THE FOREST COMPLEX
Authors:   Reshetnev Siberian State University of Science and Technology (Reshetnev University), Markovskaia Ella V. , Rubinskaya Anastasia V. ,   Reshetnev Siberian State University of Science and Technology (Reshetnev University), Voronina Elena A. ,   Reshetnev Siberian State University of Science and Technology (Reshetnev University)
Published: September 2021

The presented article is devoted to the analysis of personnel policy in the forestry industry of the Krasnoyarsk Territory, identifying problems and finding solutions. Based on the analysis of materials, the main requirements for personnel are derived. The main trends of the apparatus, methods of encouraging or punishing employees are analyzed. It was revealed that the main principle of the personnel policy of the Krasnoyarsk Territory is to ensure its maximum performance. The requirements that were imposed on staff members of the timber industry of the region have differences from traditional ideas about modern personnel policy. The main requirement in the period under review was not so much the availability of education as the presence of professionalism, length of service or enterprise. This allows us to conclude that the personnel policy of the region’s forest industry is quite high, and also suggests that such a strategy will ensure the rapid development of the region’s productive forces.
MANAGEMENT OF THE DEVELOPMENT OF INTELLECTUAL CAPITAL IN HIGH-TECHNOLOGY DESIGN-ORIENTED COMPANIES OF THE RUSSIAN FEDERATION
Authors:   Moscow State University named after M.V. Lomonosov, Parshintsev Alexander A.
Published: September 2021

The purpose of the study was to develop a conceptual and logical model of intellectual capital management in high-tech project-oriented companies of the Russian Federation. To achieve this goal, the author's approach to the definition of the concept of intellectual capital in high-tech project-oriented companies was proposed and its structure was developed, taking into account the multidimensional nature of the studied economic category. The key indicators of intellectual capital in high-tech project-oriented companies in Russia are also analyzed and based on them, a method for calculating the integral indicator of intellectual capital in high-tech project-oriented companies is developed, the purpose of which is to conduct a comparative regional analysis and analysis of the dynamics of the level of intellectual capital in high-tech project-oriented companies as a whole and its individual components. As a result of testing the methodology for calculating the integral indicator, the leading and lagging regions were identified for each sub-index of the integral index of intellectual capital: human capital, information and reputation capital, and the capital of intellectual labor achievements. Taking into account the obtained conclusions, a conceptual and logical model of intellectual capital management in high-tech project-oriented companies was justified, and the effectiveness of its implementation was proved by predicting the levels of one of the most important indicators of intellectual capital in high-tech project-oriented companies at the macro level — the share of innovative goods, works, services in the total volume of goods shipped, works performed, services rendered by high-tech project-oriented companies.
ECOLOGICAL MIGRATION FROM CENTRAL ASIA TO RUSSIA
Authors:   Institute for Demographic Research FCTAS RAS, Lukyanets Artem S. , Ochirova Galina N. ,   Institute for Demographic Research FCTAS RAS, Maksimova Anastasia S. ,   Institute for Demographic Research FCTAS RAS
Published: September 2021

Developing countries and low-income countries with rapidly growing populations and underdeveloped agricultural technologies are most vulnerable to climate change and natural disasters. The countries of Central Asia are already exposed to the impact of natural and climatic changes due to insufficient financial and technical capabilities to overcome negative climatic and environmental phenomena. The authors predict an increase in the ecological migration of the population from Central Asia to Russia due to the visa-free regime, territorial proximity, established migrant social networks and other factors, which partially will compensate for the Russian population decline. Without a legal channel for environmental migration, these flows will be forced to use the labor migration channel. However, there are a number of potential negative consequences that need to be further scrutinized.
TAJIK COMMUNITIES IN RUSSIAN REGIONS DURING THE COVID-19 PANDEMIC: EMPLOYMENT AND SOLIDARITY
Authors:   Institute for Demographic Research FCTAS RAS, Ryazantsev Sergey V. , Vazirov Zafar K. ,   Institute for Demographic Research FCTAS RAS, Kasymov Osim K. ,   Institute for Demographic Research FCTAS RAS
Published: September 2021

In the course of field research, statistical and sociological data were collected on the number, socio-demographic structure and problems of Tajik migrants in various regions of the Russian Federation. During the COVID-19 pandemic in Russia, Tajik migrants faced social and economic difficulties. The pandemic has significantly complicated the situation of Tajik citizens — temporary labor migrants in Russia. Many were unable to leave Russia before the borders were closed, and during the lockdown they lost their jobs and sources of income. The loss of a job turned into problems both for the migrants who remained in Russia and for their families, who could not receive remittances from Russia. Many labor migrants were forced to look for work, adapt to the new socio-economic situation, experienced pressure from the security forces, lost their health and were in a state of stress. Labor migrants from Tajikistan, who initially lost income during the lockdown in April-May 2020, were gradually able to adapt to the new socio-economic conditions and restore their monetary income, continuing to provide assistance to their families in their homeland. Three types of Tajik public associations in Russia have been identified and described: organizations positioning themselves through the ethnocultural component and carrying out cultural projects; organizations providing various types of assistance to citizens and immigrants from Tajikistan (for example, labor migrants); organizations uniting representatives of socio-demographic groups from Tajikistan (for example, working with youth). The article also analyzes the forms of solidarity of Tajik communities during the COVID-19 pandemic in Russia; it is revealed that the main burden of supporting Tajik migrants was carried by ethnic entrepreneurs and non-governmental organizations.
THE RESULTS OF THE INTERREGIONAL POPULATION EXCHANGE IN RUSSIA FOR 1993-2019
Authors:   Institute of Socio-Economic Studies of Population FCTAS RAS, Rybakovsky Oleg L. ,   Institute for Demographic Research FCTAS RAS
Published: September 2021

The article examines the components of the balance of interregional migration of the Russian population for 27 post-Soviet years, from 1993 to 2019. The main macro-regions of Russia and the results of their interregional migration development for the period are being investigated. Trends and patterns are revealed. The first of them is a continuation of the super-concentration of the population in the first five regions — interregional migration recipients of the country (Moscow, Moscow region, St. Petersburg, Leningrad region and Krasnodar region) due, first of all, interregional migration. The latter as a whole for the period ranged from 3/4 to 4/5 of their migration growth. The balance of population placement in Russia continues to break down. All this is happening under the influence of market mechanisms and does not stop, but, on the contrary, is amplified in the 21st century. The steps of the authorities in this area remain not effective enough. The first five regions are fueled by migration through the country's most important territories, such as Siberia, the Far East and the European North, as well as at the expense of most other territories. Perhaps the only positive development in inter-regional migration in recent years is the increase in the outflow of predominantly rural populations from the overpopulated republics of the North Caucasus.
CURRENT TRENDS IN THE DEVELOPMENT OF ECONOMIC COOPERATION BETWEEN RUSSIA AND MONGOLIA
Authors:   Institute of Economics, Russian Academy of Sciences, Lezhenina Tatiana V.
Published: September 2021

In the post-Soviet era, after a period of stagnation of the 90s, Russia and Mongolia began to actively cooperate, using and updating the economic potential created during the years of cooperation between Mongolia and the USSR. Goal. Explore modern conditions for the transition from stagnation in relations between Russia and Mongolia to cooperation. Tasks. Assess the readiness of the two countries to resume wide-ranging communications on mutually beneficial conditions. Methodology. The use of methods of scientific knowledge, the experience of economic relations of large and small countries in conditions of instability of the world economy, new threats and challenges in the XXI century. Results. It is proved that on the basis of mutually beneficial economic cooperation and coordination of domestic and foreign policies, Russia and Mongolia have created guarantees to maintain peace and promote integration in the Asia-Pacific region. Findings. Using the example of studying bilateral relations between Russia and Mongolia together with tripartite ones in the new Russia-Mongolia-China format, the possibility of reducing the dominance of China's role in Mongolia, reducing American influence and pressure on the leadership of Mongolia in order to weaken the Russian and Chinese presence is proved.
ANALYSIS OF KEY TRENDS OF THE INTERNATIONAL COAL MARKET (ON THE EXAMPLE OF THE COUNTRIES OF NORTH-EASTERN ASIA)
Authors:   MGIMO University, Cherechukin Andrey V.
Published: September 2021

The article provides an analysis of key trends in the international market, using the example of the countries of Northeast Asia. In 2019, the world coal market amounted to 1,424.5 million tons, of which 78.1% are energy grades to produce electricity and heat, and 21.9% are in metallurgy, the reserves of which are significantly less. The import coal market of the countries of Northeast Asia in 2019 was already 680 million tons, covering 48% of the entire world coal market. The paper provides an overview of the key importers and exporters of coal in the world, the quantitative and qualitative characteristics of the supplied raw materials, and analyzes the key factors affecting the pricing of coal. In the conclusions, the main trends in the international coal market of the countries of Northeast Asia are presented, including "geographical" — the shift of the center of world trade from Europe to Asia, and "types and quality of imported coal" — an increase in the share of high-quality premium energy and coking (metallurgical). Trends can be clearly seen in the countries of Northeast Asia, which actively use coal, and are making efforts to decarbonize their national economies, while intensifying inter-fuel competition with other primary energy sources.