bluuebunny/crossref_metadata_2025 huggingface dataset:
From trial and error to Equator Network
Authors: Palacios Gómez Mauricio
Published: December 2019

The dissemination of science is grounded on the reliability and value of the research literature that, through an editorial process, expresses the necessary detail to meet the reproducibility and refutability demands that underlie the scientific method. Three roles are defined in this editorial process that the researcher may assume at differing times or simultaneously, from the beginning of his career to the end of professional life: those of author, reviewer and editor.
Identification of messenger RNA of fetoplacental source in maternal plasma of women with normal pregnancies and pregnancies with intrauterine growth restriction
Authors: Ayala Ramírez Paola Andrea , García Robles Reggie , Rojas Barrera Juan Diego , Bermúdez Martha Cecilia , Bernal Villegas Jaime Eduardo
Published: December 2019

Objective: to quantify placenta-specific RNA in plasma of women carrying foetuses with intrauterine growth restriction and pregnant women with normal pregnancies.
Materials and methods: 8 pregnant women with foetuses with intrauterine growth restriction were studied as well as 18 women with uncomplicated pregnancies in the third pregnancy trimester. Total free RNA was quantified in maternal plasma by spectrophotometry and the gene expression of hPL (Human Placental Lactogen) at the messenger RNA level through technical Real Time-Chain Reaction Polymerase.
Results: plasma RNA of fetoplacental origin was successfully detected in 100% of pregnant women. There were no statistically significant differences between the values of total RNA extracted from plasma (p = 0.5975) nor in the messenger RNA expression of hPL gene (p = 0.5785) between cases and controls.
Conclusion: messenger RNA of fetoplacental origin can be detected in maternal plasma during pregnancy.
Trends of cancer incidence and mortality in Cali, Colombia. 50 years experience
Authors: Bravo Luis Eduardo , Collazos Tito , Collazos Paola , García Luz Stella , Correa Pelayo
Published: December 2019

Objetive: The Population-based Cancer Registry of Cali aims to report all new cases in permanent residents within the limits of the city of Cali. Time trends of cancer incidence and mortality are described. The registry has been in continuous operation for 50 years.
Methods: Cancer cases reports are obtained actively by visiting all sources of information: hospitals, pathology departments, hematology laboratories, radiotherapy centers, government offices where death certificates are processed and physician’s offices. It is estimated that the reporting is at least 95% complete.
Results: Drastic decreases are documented in rates for tumors causally related to infectious agents, especially cancers of the uterine cervix and the stomach. Gradual increases are documented in rates of tumors linked to affluence and the metabolic syndrome, especially cancers of the colon and the female breast. An unexpected increase in the incidence of papillary carcinoma of the thyroid gland in women is reported. Tobacco-related cancers, especially cancer of the lung, showed marked increase in incidence rates around 1970, apparently the beginning of an epidemic similar to the one reported in Western societies. But the increase in incidence stopped around 1980, resulting from a strong anti-smoking campaign launched in Colombia in the 1970s.
Conclusions: The findings have influenced prevention strategies implemented by public health authorities, specially the establishment of a city-wide program to prevent cervix cancer via widespread use of vaginal cytology and anti-smoking campaigns. Also, new population-based cancer registries have been established in other Colombian cities as well as in Ecuador.
Evaluation of an educational, theater-based intervention on attitudes toward organ donation in Risaralda, Colombia
Authors: Buitrago Juliana , Sánchez Julio C , Guerra Alvaro , Gómez Sandra V , Lucumí Leidy J , Romero César R
Published: December 2019

Introduction: The shortage of organs for transplantation is a worldwide problem and the main cause is the refusal of family members to donate. Consent to donate is influenced by many factors and educational interventions are strongly recommended.Objective: To evaluate the impact of an educational, theater-based strategy on the attitudes toward organ donation.Methodology: This study employed an intervention using theater as the central tool. The impact of this intervention on the intention to donate was assessed through a controlled, prospective, non randomized designed study. The sample consisted of 1,038 people. All the participants answered a survey that asked about sex, age and intent to donate. Afterward, one portion of the sample was exposed to the play, The Gift of Life, and a subsequent discussion forum that was guided by experts. The same survey was administered again after the intervention.Results: Before the intervention, donation attitudes were positive in 68.3% of the responses, negative in 6.8% and uncertain in 24.9%. Females showed a greater intent to donate while age had no apparent influence on the donation decision. Those exposed to the intervention were found to be more likely to donate and show a favorable change in attitude toward donation than those who were not exposed to the intervention.Conclusion: An educational intervention using theater is an effective tool to generate a short-term change in the intent to donate. Educational strategies should be employed to increase the rates of organ donation.
Mucocele of the glands of blandin nuhn: a case report
Authors: García-León Nathalia , Marrugo Gilberto E
Published: December 2019

Mucoceles arising from the Blandin Nuhn glands are uncommon benign lesions of the oral cavity, which by their clinical presentation may be confused with more serious diseases such as vascular lesions, pyogenic granulomas, polyps, or squamous papillomas; thereby, it is convenient to be aware of the characteristics of this entity to guide the accurate and timely diagnosis and treatment. Herein, we present a case of a 10-year-old patient with a recurrent lesion of this type, which required surgical excision and marsupialization of the same, with no evidence of recurrence during follow-up.
HIV and risk behaviors of persons of low socio-economic status, Popayan-Colombia (2008-2009)
Authors: Mueses Héctor Fabio , Pinzón María Viriginia , Tello Inés Constanza , Rincón-Hoyos Hernán G , Galindo Jaime
Published: December 2019

Objective: To determine HIV presence and risk behaviors of persons of low socio-economic status in the city of Popayan, Colombia.Methods: Cross-sectional study; between 2008 and 2009, 363 participants of Popayan signed informed consent and received pre and post HIV test counseling. Socio-demographic characteristics and history of STDs, risk behaviors and previous HIV testing were assessed. Descriptive statistics, correlations and multivariate logistic regression were calculated.Results: Mean age 33.5±10.2; 66.0% women. Frequency of HIV positive patients was 3.86% (95% CI: 1.87-5.85), greater in men (7.38%; p= 0.013). Greater frequency of HIV-positive patients was observed in people age 29-37, those without a stable partner, and those with history of risky alcohol consumption (more than five drinks in 2 hrs).Conclusions: HIV-positive patients frequency in this population was greater than national estimate for general population, aged 15-49 in Colombia, with even greater frequency in men. This study suggests that characteristics associated with low socioeconomic status, in economically active population, without a stable partner and with risky alcohol use, can potentially increase risk of HIV infection
A numerical well model considering capillary end effect for the low-permeability gas reservoir
Authors: Yao Yu-Min , Shi An-Feng , Wang Xiao-Hong , Liu Zhi-Feng
Published: December 2019

In the recovery of low permeability reservoir, the capillary pressure has an important effect, which may reduce gas production. Due to the capillary end effect, there are two flow patterns in the vicinity of the production well: both water and gas phases can flow into the production well and only gas phase can enter the production well. Based on the analytical equations of one-dimensional radial flow considering the capillary end effect, an alternative numerical well model for low permeability gas reservoir is constructed. Numerical examples show that the proposed model can reflect the dramatic change for saturation and gas-phase pressure in the vicinity of the production well both for two flow patterns, and therefore can predict the gas and water productions accurately at different grid scales. In contrast, the original Peaceman well model for multi-phase flow, which is directly extended from that for single-phase flow, only can provide good prediction under the condition of that the grid size is enough small. Especially, for the original Peaceman well model, this problem is out of control since it is difficult to estimate a suitable grid size.
Notes on the Poetics of Parajanov
Authors: Abrahamian L. A.
Published: December 2019

The author in the form of notes discusses the poetics of Parajanov’s creativity – his realized and unrealized films, collages and life episodes. The film “The Color of Pomegranates” is analyzed in more detail, in which the author acted in a few episodes and is therefore familiar with some of the inner sides of its creation. It is shown how Parajanov visualizes the poetry of the 18th century poet and ashugh (bard) Sayat-Nova, building a new type of poetic cinema, using visual rhymes and repetitions. When the film director was deprived of the opportunity to make movies, he created collages – “pressed films”. The Parajanovian methods of creating collages and the collage principle of his films are explored. The sources and tendencies of the development of Parajanov’s artistic works, his understanding of the canon and improvisation, methods of constructing and transforming images are analyzed. The film director’s adherence to universal color classifications (red, white, black) is revealed with the apparent polychrome coloring of his films and to multivalued and archetypical semantic images, such as “window-cage” or “window-frame-mirror” triad, the last member of which allows the director to operate with twin and androgynous images.
Ethnography of Prison According to Parajanov
Authors: Mikayelyan A. G.
Published: December 2019

In the article, the prison period of Sergei Parajanov’s art is examined – Parajanov served his sentence in 1973–1977 in the high security camps in Ukraine. Following the graphic works, collages and film scenarios which he created in the prison, one can conceive of the everyday life in the Soviet prison of 1970s –1980s, more than that, get an outline of the ethnography of the Soviet prison. Parajanov often uses ethnographic realities and attributes in his movies, some of these movies are even considered to be a specific variety of ethnographic cinema. However, there is an opinion that the film director, while reflecting ethnographic realities, no less created pseudoethnographic ones. In this regard, his works of the prison period are something different from the usual Parajanovian fantasies. Unlike the authors who studied the ethnography of the prison, even those who relied on their own experience (for example, L. Samoilov), Parajanov created a significant part of his works of prison content in the camp, like an ethnographer in the field, although there are also works that he created or supplemented after prison, again like an ethnographer, relying on his field notes. In other words, his works of the prison period are much closer to the genre of ethnography than his “ethnographic” films. The article also discusses the problem of the representation of Parajanov’s works of the prison period in the museums. Are they samples of prison art, a representation of a certain period in the author’s biography, or a kind of the prison ethnography?
Bistable Texts: On Cognitive Mechanisms of Maintaining of Unresolved Ambiguity
Authors: Akhapkin D. N.
Published: December 2019

The article introduces the concept of bistable texts in literature, that reflects a notion of bistable images in cognitive psychology. Bistable texts are the texts that can be read in two different and not intersected semantic plans. They are characterized not by uncertainty but the certainty of two equally plausible interpretations, each one of which is independent and sovereign when it occupies the conscious stage. The main features of the bistable text are exclusivity, inevitability and randomness. As an example of bistable text one of the poems written by Russian poet Vladimir Strochkov is analyzed.
The Observer as a Plot Position in the Poetry and Prose by N. D. Khvoshchinskaya
Authors: Ponomareva Anastasia A.
Published: December 2019

The article presents investigation the phenomenon, characteristic for poetry and prose by N. D. Khvoshchinskaya. It is actualization of the observer figure in the plot. The author determines poems by N. D. Khvoshchinskaya have stories micro-plots. The center is a lyrical heroine watching else’s life. The poetic creation of this plot position is eclectic. The motif theme is developed with the help of romantic and naturalistic clichés. On the one hand, the author reproduces the romantic situation of social alienation, elegiac motives of memory, loss, etc. On the other hand, the author actualizes the theme of the influence of the environment on the person, the idea of useful work, etc. The article shows the plot position, formed in poetry, organically entered into prose in the heyday of the “fiction talent” by writer. In prose works the lyrical component is absorbed by the plot. The observer is not only not removed from the events, but also actively involved in them. The article gives a thorough description of the story “Behind the wall” (1862). This story is exceptionally representative. The narrator watching the love story of his neighbors is brought to the fore. Fable observation is presented through a situation of listening, not peeping. The actualization of the poetic principle in the prose plot leads to the weakening of “fabulousness”. The constructive beginning, forming a prose plot, is the reflection of the narrator. Else’s love story is the background of his experiences. The shift of the plot emphasis from the lovers to the narrator leads to the fact that the social component of the plot, associated with the issue of female emancipation, is “extinguished”, there is a psychologization of the narrative. In conclusion that the figure of the observer in poetry and prose by N. D. Khvoshchinskaya has an important plot value, organizing the semantic core of the plot. In the poetic and prose versions of the plot position is repeated the same motif theme. In the process of observation before the lyrical heroine and the hero-narrator open the opportunity to live else’s life. The ways of its development differ in the poetry and prose by N. D. Khvoshchinskaya.
Principles of creating technology for modeling and forecasting the development of regional fuel and energy complexes of Russia and Mongolia in respect the energy cooperation between the two countries
Authors: Казаков Александр Леонидович , Лемперт Анна Ананьевна , Столбов Александр Борисович , Санеев Борис Григорьевич , Попов Сергей Петрович
Published: December 2019

Статья посвящена разработке вычислительной технологии для сценарного моделирования и прогнозирования взаимосвязанного развития национальных топливно/энергетических комплексов России и Монголии с учетом межстрановой торговли топливно/энергетическими ресурсами. Целью исследования является создание методологической базы для определения наиболее перспективных вариантов двухстороннего взаимодействия, которая позволит давать обоснованные оценки эффективности проектам сотрудничества России и Монголии в области энергетики. Научной основой для создаваемой технологии послужили принципы агентного имитационного моделирования, в соответствии с которыми изучаемые объекты рассматриваются как элементы многоагентной системы.

Для создания агентной имитационной модели (АИМ) топливно/энергетического комплекса России и Монголии выбрано инструментальное средство разработки агентных имитационных моделей Adskit. Проведено обоснование выбора программных средств, разработаны методические принципы и архитектура АИМ. Построена математическая модель для задачи прокладки маршрутов протяженных энергетических объектов, имеющая вид специальной задачи вариационного исчисления, для её решения предложен авторский алгоритм на основе принципов геометрической оптики.
Study of the vectorization efficiency of loop nests with an irregular number of iterations
Authors: Рыбаков Алексей Анатольевич , Шумилин Сергей Сергеевич
Published: December 2019

Векторизация вычислений является важной низкоуровневой оптимизацией, используемой для создания высокоэффективного параллельного кода. Особенности набора инструкций AVX-512 позволяют применять векторизацию для сложного программного контекста, в частности для гнезд циклов и циклов с сильно разветвленным управлением. При использовании векторных инструкций для контекста с неизвестным профилем исполнения существует опасность низкой эффективности векторизации. Особенно ярко это проявляется при векторизации гнезд циклов с нерегулярным числом итераций внутреннего цикла.

В статье рассматривается практический подход к векторизации гнезд циклов, основанный на предикатном представлении программы. В качестве примера приводится реализация сортировки Шелла, компактная реализация которой состоит из гнезда циклов, в котором количество итераций внутреннего цикла носит нерегулярный характер и зависит от номеров итераций внешних циклов. Такой контекст является крайне неудобным для векторизации.

Приводится сравнение теоретической и практической эффективности векторизации сортировки Шелла, рассматриваются особенности этого программного контекста и объясняется их негативное влияние на производительность векторизованного кода. Полученные результаты могут быть использованы исследователями и разработчиками программного обеспечения для обнаружения причин низкой эффективности векторизации программного кода с похожими особенностями.
Dethioacylation by Sirtuins 1–3: Considerations for Drug Design using Mechanism-based Sirtuin Inhibition
Authors: Rajabi Nima , Lund Nielsen Alexander , Olsen Christian Adam
Published: December 2019

The sirtuin enzymes are potential drug targets for intervention in a series of diseases. Efforts to inhibit enzymes of this class with thioamide- and thiourea-containing, substrate-mimicking entities have produced a number of high-affinity binders. However, less attention has been dedicated to the investigation of the stability of these inhibitors under various conditions. Here, we provide evidence of unprecedented degree of cleavage of short-chain epsilon-N-thioacyllysine modifications meant to target these sirtuins and further provide insights into the serum stability of compounds containing both thioamides and thioureas. Our study questions the utility short-chain thioamide-based inhibitors of sirtuins for drug development and points to application of mono-alkylated thiourea-based chemotypes as more promising for targeting sirtuins 1 and 3, in particular.
Erişkinlerde akılcı ilaç kullanımı farkındalık ölçeğinin geliştirilmesi: Geçerlik ve güvenirlik çalışması
Authors: AKTAŞ Hakkı , SELVİ Hüseyin
Published: December 2019

Amaç: Bu çalışmada 18 yaş üstü bireylerin akılcı
ilaç kullanımı konusundaki farkındalıklarını belirlemeye yönelik bir ölçek
geliştirmek amaçlanmıştır. Yöntem:
Çalışmaya 18 yaş üstü 402 birey katılmıştır. Çalışma kapsamında elde edilen
veriler 22 maddelik 5’li Likert tipinde bir ölçek deneme formu kullanılarak
elde edilmiştir. Elde edilen veriler üzerinden betimsel istatistikler, açımlayıcı
faktör analizi, doğrulayıcı faktör analizi, bağımsız gruplar t testi uygulanmış
ve Cronbach alfa katsayısı hesaplanmıştır. Bulgular: Açımlayıcı faktör analizi
sonuçları ölçeğin tek faktörlü 3 bileşenli bir yapı sergilediğini ve 15
maddeden oluştuğunu göstermiştir. Tek faktörlü üç bileşenli bu yapı doğrulayıcı
faktör analiziyle de doğrulanmıştır. Ölçeğin alfa güvenirliği 0.83 olarak
belirlenmiştir. Sonuç: Ölçeğin
akılcı ilaç kullamını farkındalığını ölçmeye yönelik güvenilir ve geçerli bir
ölçek olduğu sonucuna varılmıştır.
Effects Of Genre Based Approach (GBA) In EFL Reading Comprehension And Writing
Authors: Montero-Arévalo Sindy Johana
Published: December 2019

The present paper puts under examination the effects of Genre Based Approach (GBA) on 9th grade students from a city in the Caribbean coast of Colombia. The study has the purpose of analyzing how GBA affects reading comprehension and writing. We implemented GBA for six sessions using instruments for data collection that included tests, questionnaires and interviews. The overall findings show that students’ reading comprehension, writing, motivation and autonomy improve after the implementation of GBA; as a result, the students were able to understand, explain and recreate the genres that were part of the study.
Inhibitory effects of cardamonin on compound action potentials in frog sciatic nerves and the possible involvement of opioidergic pathway
Authors: Sambasevam Yogesvari , Siong Jiun Wong , Ghazali Farihah Hanani , Amir Ramadan Ammar Izzati , Omar Farouk Ahmad Akira , Sulaiman Mohd Roslan , Hussain Mohd Khairi , Perimal Enoch Kumar
Published: December 2019

Introduction: Active compounds derived from plants are able to inhibit nerve conduction. Cardamonin, a naturally occurring chalcone, manifests anti-nociceptive, anti-inflammatory and anti-neuropathy properties. Consequently, cardamonin may potentially inhibit nerve action potential, whereby, it affects the nerve conduction. Compound action potential is the sum of the activity which is measured from a nerve trunk. Objective: The study was conducted to investigate the inhibitory effect of cardamonin on compound action potentials and its possible mechanism of action on frog sciatic nerve. Methodology: Compound action potentials were recorded from frog sciatic nerve by using the AD instrument. Sciatic nerve was isolated from the frog and placed in Ringer’s solution. Stimulating electrodes were used to stimulate the nerve and recording electrodes were used to record compound action potentials. Compound action potential of the nerve were recorded before and after treatments [vehicle, cardamonin (0.5, 1 & 2 mg/ml) & morphine (3mg/ml)]. To investigate the involvement of opioidergic system, the nerve were pre-treated with naloxone and followed by cardamonin. All the data were recorded and analysed via LabTutor software. The data were analysed by using Two-way ANOVA followed by Bonferonni’s post hoc test with significant value at P < 0.05. Results: The outcomes showed that all the doses of cardamonin significantly reduced the peak amplitude of compound action potential in frog sciatic nerves. Besides, co-treatment of naloxone and cardamonin significantly (P < 0.001) reversed the effect of cardamonin on peak amplitude of compound action potential, suggesting the involvement of opioid receptors to inhibit nerve conduction. Conclusion: Cardamonin reduces the nerve signal conduction via activation of opioid receptors to modulate pain and contribute to the analgesic effects.
Elucidating Lineage-Specific Myelotoxicity and Chromosomal Abberation Status in Hydroquinone-Exposed Hematopoietic Stem / Progenitor Cells
Authors: Mohd Idris Julia , Abdul Hamid Zariyantey , Ng Khen Eng , Chow Paik Wah , Shuib Salwati , Mathialagan Ramya Dewi
Published: December 2019

Benzene exposure has been associated with hematotoxicity and leukemogenicity. However, the impact of benzene exposure on complex microenvironment of Hematopoetic Stem Cells (HSCs) niche, comprising of HSCs and lineage-specific progenitors remains elusive. Thus, a study on benzene-targeting HSCs niche could uncover mechanism linking benzene to HSCs niche alteration. This study evaluates the lineage-specific responses following exposure to a benzene metabolite, namely hydroquinone (HQ) in targeting HSCs and myeloid-committed progenitors. Freshly isolated murine bone marrow cells (BMCs) were exposed to HQ at series of concentrations (0 – 50 µM) for 24 hours; followed by cell viability analysis using MTT assay. Chromosomal aberration (CA) status was determined using karyotyping analysis. Expression of surface antigen for HSCs (Sca-1) was confirmed by flow cytometer. Lineage-specific myelotoxicity was studied using the colony-forming unit (CFU) assay for the following myeloid progenitors: CFU granulocyte /erythrocyte /macrophage /megakaryocyte (CFU-GEMM), CFU-granulocyte/macrophage (CFU-GM), CFU-granulocyte (CFU-G), CFU-macrophage (CFU-M), CFU-erythroid (CFU-E) and Burst-forming unit erythroid (BFU-E). HQ reduced (p<0.05) viability of BMCs at 25 µM and 50 µM with the IC10, IC25, and IC50 were at 17 µM, 23 µM and 35 µM, respectively. Increased (p<0.05) frequency of CA was observed in HQ-treated group as compared to control. Reduced (p<0.05) Sca-1+ cells at 17 µM, 23 µM and 35 µM indicates cytotoxic effect of HQ targeting HSCs population. Reduced (p<0.05) total colony counts were noted following HQ exposure at 6.25 µM and a complete inhibition of colony growth were observed at higher concentration (12.5 µM). HQ reduced (p<0.05) the growth of CFU-GEMM, CFU-GM and CFU-G at 6.25 µM, while the growth of CFU-M, CFU-E and BFU-E were not remarkably affected at lower concentrations (1.56 µM and 6.25 µM). Conclusively, HQ induces chromosomal aberration and cytotoxicity on HSCs with notable lineage-specific responses in governing benzene-mediated myelotoxicity targeting HSCs niche.
Association of Immunoglobulin G Abnormalities in Diseases: A Mini Review
Authors: Kow Audrey Siew Foong , Wan Zahidi Nuha Fahimah , Tham Chau Ling
Published: December 2019

Immunoglobulins are antibodies that play important roles in preserving our immune system. They have the ability to initiate humoral responses and remove antigen from the body. Out of the five major isotypes of immunoglobulins, IgG are most abundantly found in human serum. Abnormalities – deficiency or elevation in the level of IgG are found to be associated to the occurrence of several autoimmune diseases. These may include rheumatoid arthritis, Crohn’s disease, Mikulicz’s disease, Kuttner’s tumour and Hashimoto’s thyroiditis. Apart from autoimmune diseases, IgG has been found to play a role in initiating anaphylaxis, a severe and life threatening form of allergy and lately it has been discovered in cases of dengue virus infection too. It is important to acknowledge the roles of IgG on diseases especially subclass IgG4 which the elevation has been tied to numerous diseases such as Kuttner’s tumour and Hashimoto’s thyroiditis hence termed IgG4-related diseases. In addition, the roles of IgG in anaphylaxis are of importance, too, as IgG has been used in allergy immunotherapy. Hence, this review is a mini compilation of effects of IgG abnormalities based on their subclasses. Hopefully it will provide insightful understanding on the development of diagnostic and therapeutic courses for the aforementioned IgG abnormalities in the future.
Protective effect of aqueous extracts from Canarium odontophyllum Miq. leaf on liver in streptozotocin-induced diabetic rats
Authors: Budin Siti Balkis , Kumar Shashi , Abd Warif Nor Malia , Mohd Saari Shafikha , Basri Dayang Fredalina
Published: December 2019

The fruit of Canarium odontophyllum Miq. are a traditional delicacy in Borneo for its anti-aging benefit. This study evaluated the protective effect of C. odontophyllum leaf aqueous extract on the damaged liver in streptozotocin-induced diabetic rats. A total of 30 male Spraque-Dawley rats (150-250g) were randomly divided into three groups: control group, diabetic without treatment and diabetic treated with 300 mg/kg aqueous extract once a day for 28 days. The diabetic condition was induced by intravenous injection of 65 mg/kg streptozotocin (STZ). The blood was collected to assess the biochemical changes and the oxidative stress marker whereas the liver section was examined for morphological changes. Result showed that the level of blood aspartate transaminase (AST), alanine transaminase (ALT), total bilirubin, gamma-glutamyl transferase (GGT) and alkaline phosphatase (ALP) in STZ-induced rats treated with C. odontophyllum were significantly reduced (p<0.05) compared to STZ group. Oxidative stress test showed lower level of malondealdehid (MDA) and protein carbonyl but significantly (p<0.05) higher activity of GSH, SOD and GPx compared to untreated diabetic group. Abnormal cells were not detected from the histological observation. These findings demonstrated that the aqueous extract of C. odontophyllum has the potential to provide protective effect against liver damage in diabetic rat.
Effect of Break Time on the Upper Extremity Musculoskeletal Disorder Development among Intensive Computer Users in Malaysia
Authors: Manoharan Thulasi , Mohd Yusuff Rosnah , Zulkifli Norzima , Perimal Enoch Kumar
Published: December 2019

Upper Extremity musculoskeletal disorder (MSD) has become a common problem among office workers in Malaysia. Studies have shown that an appropriate work-rest schedule can reduce fatigue and MSDs among office workers. In Malaysia, there has been an increase in the occurrence of MSDs, especially in work that require intensive computer use. Operators who used computers continuously for more than 4 hours a day have shown to develop CTDs. Studies on the effect of break time on the performance of office workers in Malaysia are still lacking. As such this study was aimed to evaluate effect of work rest schedule on the discomfort, performance and muscular load levels of computer users in Malaysia. The effect of break time starting with no break, one minute and 30 seconds break interval were carried out on the 15 subjects. EMG was measured for each task given. Performance which was calculated by multiplying speed and accuracy (WPM) showed 30 seconds break was 13.5% higher than 1 minute break and 20.14% higher than schedule with no break. EMG analyses showed 30 seconds have lowest mean AEMG which was 0.035 for flexor carpi ulnaris and 0.0331 for radialis muscles. It also recorded least discomfort scale for upper extremity muscles compared to the other two schedules. This study showed that more frequent microbreaks can improve performance of office workers and reduce MSD problem from occurring.
Profiles and Biological Values of Sea Cucumbers: A Mini Review
Authors: Masre Siti Fathiah
Published: December 2019

Sea cucumbers, blind cylindrical marine invertebrates that live in the ocean intertidal beds have more than thousand species available of varying morphology and colours throughout the world. Sea cucumbers have long been exploited in traditional treatment as a source of natural medicinal compounds. Various nutritional and therapeutic values have been linked to this invertebrate. These creatures have been eaten since ancient times and purported as the most commonly consumed echinoderms. Some important biological activities of sea cucumbers including anti-hypertension, anti-inflammatory, anti-cancer, anti-asthmatic, anti-bacterial and wound healing. Thus, this short review comes with the principal aim to cover the profile, taxonomy, together with nutritional and medicinal properties of sea cucumbers.
Pendampingan Ibu-Ibu PKK RT 04 Wonokromo I Pleret Bantul Dalam Melakukan Perencanaan dan Implementasi Bisnis, Proses Produksi, dan Pengembangan Produk Usaha Rintisan Wono Batik Jumputan
Authors: Zabidi Yasrin
Published: December 2019

Usaha Wono Batik Jumputan pada dasarnya merupakan usaha rintisan ibu-ibu PKK Wonokromo I berbasis rumahan yang masih kebingungan dalam menjalankan usaha dengan baik, khususnya kurangnya pengetahuan dalam  perencanan bisnis batik (aspek pasar meliputi konsumen, pasar, pesaing, aspek teknik meliputi perencanaan bahan baku utama dan pendukung, alat, sumber daya manusia), implementasi bisnis (cara memasarkan produk), pengelolaan keuangan, pengembangan/inovasi produk, sehingga berdampak tidak optimalnya usaha yang dijalankan. Salah satu faktor penyebabnya adalah kurangnya pengetahuan, keterampilan sumber daya manusia dalam menjalankan suatu usaha/bisnis. Selain itu usaha rintisan ini  relatif masih lambat untuk berkembang karena faktor modal usaha yang sangat terbatas. Solusi untuk mengatasi permasalahan  kurangnya pengetahuan, keterampilan sumber daya manusia dalam menjalankan suatu usaha/bisnis adalah dengan memberikan pendampingan bimbingan usaha. Oleh karena itu dalam kegiatan Pengabdian pada Masyarakat T.A. 2018/2019 ini, pengusul melakukan kegiatan pendampingan untuk membina dan membimbing ibu-ibu PKK di RT 04, Wonokromo I, Wonokromo, Pleret, Bantul dalam melakukan perencanaan bisnis batik (aspek pasar meliputi konsumen, pasar, pesaing, aspek teknik meliputi perencanaan bahan baku utama dan pendukung, alat, sumber daya manusia), implementasi bisnis batik (cara dan media promosi, cara memasarkan produk batik, analisis SWOT, analisis kinerja), mampu melakukan proses pembuatan batik jumputan, membuat laporan keuangan yang sederhana serta mampu memunculkan ide-ide motif batik jumputan agar usaha rintisan ini berkembang dengan baik dan dapat meningkatkan kesejahteraan masyarakat.
Gri Tahmin Modeli ve Uygulaması
Authors: BİLGİL Halis , OZTURK Zafer , OZGUL Emine
Published: December 2019

Gri teori, zayıf bilgi veya bilgilerin eksik olduğu sistemlerle
ilgilenen etkili bir teoridir. Bu teoride az sayıda veriden faydalanarak
gelecek zamanlar için etkin ve oldukça yaklaşık tahminler
oluşturulabilmektedir. Gri modelleme yöntemi, gri sistemler teorisinin bir alt
dalı olup, modelleme işlemi ilgili fark denklemleri ve diferansiyel denklemler kullanılarak
yapılır. En küçük kareler yaklaşımı sonuçların uygunluğu üzerinde önemli bir
rol oynamaktadır. Kesinliği ve kullanışlılığı ile gri tahmin modellerinin
temelini oluşturan GM(1,1) modelleme yöntemi kullanılarak, Aksaray ilinden
ileriki yıllarda elde edilecek vergi gelirlerinin tahmini yapılmıştır. Bu
tahminler başta yerel yönetimler olmak üzere ekonomik politikalar için oldukça
faydalıdır.
Penerimaan Zakat dan Penurunan Kemiskinan di Aceh: Peran Dana Otonomi Khusus Sebagai Pemoderasi
Authors: Muliadi Muliadi , Amri Khairul
Published: December 2019

This study aims to analyze the effect of the zakat revenue on poverty by using the special autonomy fund (DOK) as a moderating variable. Using panel data of 15 districts from Aceh province from 2011 to 2016, Moderated Regression Analysis (MRA) was used to analyze the functional relationship. The study found that zakat revenue and DOK had a negative and significant effect on poverty reduction. The negative impact of DOK on poverty partially more significant compared to the negative impact of zakat revenue. The existence of DOK does not only play a role as a predictor variable but also moderates the effect of zakat revenue on poverty reduction in Aceh.
PENENTUAN FAKTOR PENDORONG PENYEBARAN WABAH PENYAKIT BERDASARKAN METODE AHP - DELPHI (STUDI KASUS: KLB LEPTOSPIROSIS DI KABUPATEN BANTUL)
Authors: Yuliana Diyah
Published: December 2019

Leptospirosis merupakan salah satu penyakit zoonosis yang terabaikan, namun memiliki tingkat kefatalan yang cukup tinggi. Penyebaran epidemiologis bakteri leptospirosis dipengaruhi oleh lingkungan dan aspek sosio-demografis. Leptospirosis menjadi masalah yang penting dan genting di Provinsi Daerah Istimewa Yogyakarta, khususnya Kabupaten Bantul. Tercatat sejak tahun 2009 – 2014 banyak kasus leptospirosis dilaporkan. Peningkatan kasus leptospirosis di Kabupaten Bantul terjadi pada tahun 2011 sehingga dinyatakan sebagai Kejadian Luar Biasa (KLB). Analisis risiko sebagai langkah mitigasi dapat dilakukan untuk menentukan penyebaran, mengelompokkan dan memprediksi terjadinya leptospirosis di suatu wilayah. Sebelum membuat analisis risiko, perlu ditentukan faktor apa saja yang menjadi pendorong penyebaran wabah leptospirosis di Kabupaten Bantul. Melalui metode AHP – Delphi dapat diketahui bahwa faktor pemukiman yang padat dan faktor kejadian banjir dinilai merupakan faktor pendorong paling kuat dalam penyebaran KLB leptospirosis di Kabupaten Bantul. Faktor keberadaan lahan basah dan faktor kepadatan penduduk juga dinilai memiliki peran dalam penyebaran KLB leptospirosis di Kabupaten Bantul.Kata kunci: leptospirosis, wabah, faktor pendorong, AHP, Delphi
KEMAMPUAN PENANGANAN TERHADAP ANCAMAN BENCANA TSUNAMI DI WILAYAH PESISIR KOTA CILEGON
Authors: Yuliana Diyah Krisna , G. Tejakusuma Iwan
Published: December 2019

Wilayah pesisir Kota Cilegon merupakan daerah rawan gempa dan tsunami, karena posisinya yang berbatasan langsung dengan Selat Sunda yang  memiliki bahaya gempa dan dekat dengan Gunung Anak Krakatau. Pada tahun  1883 pernah terjadi tsunami besar akibat letusan Gunung Krakatau yang telah memakan korban sekitar 36.000 jiwa. Risiko bencana tsunami akan sangat besar bagi Kota Cilegon karena terletak di wilayah pesisir dengan tingkat kepadatan penduduk dan aktivitas perekonomian yang cukup tinggi. Risiko bencana yang tinggi dapat diminimalisir jika suatu wilayah memiliki tingkat kemampuan penanganan  atau kapasitas yang tinggi. Oleh karena itu kajian tentang kemampuan penanganan terhadap bencana tsunami di kota ini menjadi sangat penting. Penilaian kemampuan penanganan terhadap ancaman bencana tsunami ini dilakukan dengan menggunakan metode MCE (Multi Criteria Evaluation) dan teknik GIS (Geographical Information System). Kesehatan, kesiapsiagaan dan jumlah penduduk bekerja adalah tiga indikator penting yang digunakan dalam penilaian kemampuan penanganan di wilayah pesisir Kota Cilegon. Berdasarkan analisis MCE dan SIG diketahui bahwa Desa atau Kelurahan Randakari dan Kubangsari adalah desa atau kelurahan yang memiliki kemampuan penanganan terhadap bencana tsunami yang paling tinggi.
MITIGASI BENCANA KEKERINGAN DI KABUPATEN PELALAWAN, RIAU
Authors: Hernaningsih Taty
Published: December 2019

Musim kemarau yang berkepanjangan di tahun 2015 ini berimplikasi pada bencana kekeringan di sejumlah wilayah di Indonesia. Kekeringan itu juga melanda  propinsi Riau  dan kondisi daerahnya dari tahun ke tahun  semakin parah karena  kemarau panjang. Musim kemarau di bulan Juli 2015, sebanyak 17 kecamatan yang tersebar di enam kabupaten dan kota di tengah Pulau Sumatera itu tidak mengalami hujan selama lebih dari 30 hari. Keadaan ini menyebabkan bencana kekeringan danberdampak terhadap krisis air  di lokasi tersebut serta daerah sekitarnya  seperti di kabupaten Pelalawan. Penelitian dilakukan terhadap bencana kekeringan yang terjadi dan mitigasi yang dilakukan untuk mengatasi bencana tersebut yang dapat diterapkan di kabupaten Pelalawan, Riau. Bencana kekeringan yang termasuk klasifikasi kekeringan sosio-ekonomi telah terjadi di kabupaten Pelalawan berupa kekurangan sumber air, kekeringan sumber air sungai dan kekeringan di lahan gambut. Mitigasi untuk mengatasi bencana kekeringan dapat dilakukan dalam jangka panjang maupun jangka pendek. Mitigasi jangka pendek di kawasan Teknopolitan Pelalawan yaitu dengan pembuatan sumur air tanah dalam dengan kedalaman sampai 110 meter. Sedangkan mitigasi jangka panjang di kabupaten  tersebut dengan pembangunan sekat kanal. Rekayasa teknologi yang lebih tinggi hingga saat ini belum ada yang bisa diterapkan untuk skala nasional.
ENGINEERING STUDENTS’ ATTITUDES TOWARD STATISTICS: A MULTI-CASE STUDY
Authors: SARIKAYA Kadir , EMMİOĞLU SARIKAYA Esma
Published: December 2019

This study investigated the attitudes toward statistics of the electrical & electronics engineering and geomatic engineering students who were enrolled in a Turkish university. Survey of Attitudes toward Statistics-36 (SATS) was used to collect data. The participants of the study were 62 Engineering students (38 male and 24 female). They were sophomore students enrolled in either electrical & electronics engineering (n=28) or geomatic engineering (n=34) departments and had not taken a university level statistics course before. Both electrical & electronics engineering students and geomatic engineering students generally had positive attitudes toward statistics; however, geomatic students tended to have more neutral attitudes at the end of the semester.
Responsabilidad Social Empresarial competitiva en Mipymes de la Sabana de Occidente, Cundinamarca
Authors: Zipasuca Quemba Francisco Javier , Cruz Páez Fabio Orlando , Rojas Ramírez Juan de Jesús , Muñoz Omar Fernando
Published: December 2019

El presente artículo de investigación muestra la importancia de la Responsabilidad Social Empresarial (RSE) y la incorporación de la misma en la planeación de las Mipymes de la Sabana de Occidente en Cundinamarca, Colombia. La metodología fue de corte mixto con diseño transversal, mediante una encuesta dirigida a los gerentes de 206 pequeñas empresas, 93 de medianas empresas y 771 de microempresas, ubicadas en ocho municipios del departamento de Cundinamarca. En el análisis se exploran las variables teóricas de Responsabilidad Social Empresarial, competitividad, stakeholders, pymes y medio ambiente, evidenciando que para implementar la RSE en Mipymes es fundamental aumentar la comprensión del concepto y fortalecer la planeación. Adicionalmente, se comprobó que el mejor punto de partida es trabajar la relación con los stakeholders, que están más conectados con el núcleo del negocio, así como las relaciones comunitarias y la sensibilización ambiental requieren de mayor atención y se pueden fortalecer desde la relación con los stakeholders.
Upgrading the Land Administration System of the Philippines through ICT: A Review of the Land Titling Computerization Program
Authors: Katigbak Jovito Jose
Published: December 2019

An effective and efficient land administration system is vital in pursuing national and local development as it ensures security of land tenure, enables citizens to utilize their land, and fosters a peaceful and stable environment. In the Philippines, the Land Registration Authority (LRA) demonstrated its commitment to adopt e-government by launching the Land Titling Computerization Project (LTCP) in 2008. Despite this major stride, the viability of the LTCP was put to the test due to a couple of challenges. Thus, this research attempts to describe the opportunities and challenges faced by the LTCP. It uses a descriptive-exploratory method as it identifies the depth of e-government development in the Philippines with a specific focus on the LTCP. The study finds that the LTCP is currently in the enhanced information services (stage 2) level based on the UN Online Service Index and basic gaps must be addressed via necessary improvements.
PENGARUH DEBT TO EQUITY RATIO TERHADAP DIVIDEND PAYOUT RATIO MELALUI RETURN ON ASSET
Authors: Santoso Rahmat Agus , Handayani Anita
Published: December 2019

Dividend distribution becomes a complicated problem due to differences in interests between  management and shareholders. Dividends are part of the profits obtained by the company during its business which are distributed to shareholders. The dividend payout ratio determines the amount of profit divided into cash dividends and retained earnings. If the retained earnings of the company are large, the profit to be paid as a dividend will be smaller. Important aspect of dividend policy is determining the appropriate profit allocation between payment of earnings as retained earnings and earnings as dividends. Analysis of the data used in this study uses Partial Least Square (PLS). Debt to Equity Ratio (DER) has a significant negative effect on Return on Assets (ROA). Debt to Equity Ratio (DER) does not directly influence Dividend Payout Ratio (DPR). Return on Assets (ROA) has a significant positive effect on Dividend Payout Ratio (DPR). Return on Assets (ROA) is not able to mediate between Debt to Equity (DER) with Dividend Payout Ratio (DPR).
ANALISIS PROGRES PENCAPAIAN MILLENIUM DEVELOPMENT GOALS PROVINSI JAWA TIMUR (Progress Analysis Of Achievement Millenium Development Goals In The Province Of East Java)
Authors: Hidayati Roziana Ainul
Published: December 2019

Problems of poverty alleviation is not an easy problem. Poverty alleviation programs should be targeted, the exact activities, the right program, the right location and the right budget. This programs will be undertaken in order to reduce poverty more in the form of charity, physical development and others that it is less well targeted. a lot of program-the program as activities which basically only be duplicated or copy paste from the previous year's activities with the intention that the budget, physical also often undertaken without first reviewing whether the local area is very requires the existence of the physical building while there are things another even more a priority for local residents to improve their welfare. And one of the frameworks that can help us understand poverty as a multidimensional problem and its measurement is with the Millennium Development Goals or also known as the Millennium Development Goals (MDGs). The results showed that the achievement of the MDGs progress in East Java of 7 (seven) existing Goal progress of his "fast" exception Target IC on Goal I. To Target IC progress in the achievement of East Java Province "slow". Districts that experienced the severity of poverty for Goal I is Sampang and Pamekasan. , Districts that experienced the severity of poverty for Goal III is Bangkalan and Pamekasan. Districts that experienced the severity of poverty for Goal IV is Probolinggo and Bangkalan. Districts that experienced the severity of poverty for Goal V is Bangkalan and Sumenep. Districts that experienced the severity of poverty for the Goal and VII are Sampang regency. Districts that have the highest poverty severity for each Goal MDG namely Bangkalan on Goal III, IV and V
Pengaruh Efisiensi dan Motivasi Kerja terhadap Kinerja Karyawan Melalui Sistem E-Procurement Sebagai Variabel Intervening
Authors: Suharyanto Agus
Published: December 2019

Penelitian ini bertujuan untuk mengetahui manfaat setelah diimplementasikan dari sistem E-Procurement  yang merupakan bagian dari SAP dalam proses Supply Chain Management (procurement) pada perusahaan PT. Petrokimia Gresik. Setelah melakukan migrasi sistem Enterprise Resource Plan tahun 2016 dan mengaplikasikan sistem E-Procurement   pada tahun 2017, dapat dilihat manfaat dari kinerja karyawan, efisiensi kerja dan kepuasan kerja. Penelitian ini menggunakan variabel intervening, dimana sistem E-Procurement  merupakan variabel tersebut. Dari akhir penelitian dapat dilihat terdapat peningkatan dari efisiensi kerja, namun tidak demikian dengan kepuasan kerja.
PENGARUH PENERAPAN TATA KELOLA, RASIO LIKUIDITAS, DAN TINGKAT EFISIENSI TERHADAP NILAI PERUSAHAAN DENGAN KINERJA KEUANGAN SEBAGAI VARIABEL INTERVENING PADA PERUSAHAAN PERBANKAN DI BEI
Authors: Wardani Bella Martina , Priyawan Sunu , Riyadi Slamet
Published: December 2019

This study aims to analyze the influence of Corporate Governance, liquidity ratios and efficiency levels on financial performance and company value that can be used as a reference for management in using good and appropriate governance so that it can benefit the company as a whole. The population in this study uses all banking companies listed on the Indonesia Stock Exchange with a sample of 21 companies. The variables used in this study are Corporate Governance that is proxied by the Board of Commissioners, Independent Board of Commissioners, Board of Directors and Audit Committee, Liquidity Ratios that use the proxy Current Ratio, Quick Ratio and Cash Ratio, Efficiency Levels that use Operational Cost-Operational Proxies , Financial Performance that uses the proxy of Return On Assets (ROA), Return On Equity (ROE) and Net Profit Margin (NPM), while the company value uses Price to Book Value (PBV), Price Earning Ratio (PER) and TOBIN'S. using Smart PLS (Partial Least Square) analysis tool to determine the effect of these variables. The results of this study indicate that Corporate Governance has a significant negative effect on Financial Performance and Corporate Values, Liquidity Ratios and Efficiency Levels have a significant positive effect on Financial Performance and Corporate Value While Financial Performance has a significant negative effect on Firm Value