bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of Scientific Techniques in Investigation of Criminal Cases in India
Authors: V. Udayakumar , Gill Simranjeet Kaur
Published: March 2023

Solving crime is a major task to the investigators and it is also considered as a serious business. Successful investigation as well as prosecutions contributes to public safety to a great extent by incapacitating violent criminals. In doing so, people build confidence in our criminal judicial system. Whenever, investigation fails, the offenders remain free and therefore, the public is at risk of harm by the offenders. Similarly if innocent person was arrested and convicted, it will be horrible injustice done to that person which causes reputation of criminal justice system. To solve this problem, it is the forensic science, which plays an important role in criminal investigation of crime cases. The scientific method of investigation helps the courts to reach at logical conclusion of an offence. Tremendous scientific and technological developments have been made in India during the last century and also intensified in the 21st century. The 20th century is often called as the age of science. Many scientific Institutions came into exist in India at the beginning of 20th Century and the flow is continued till now. Various scientific technologies such as fingerprinting, DNA profiling ,Narco-analysis, Polygraph, Brain Mapping, Electronic surveillance, Computer forensics etc. are being used by the investigating officers to bring out the real facts of the case. At present, the Government has created a lot of forensic facilities for the disposal of cases in timely manner through scientific investigation. This paper aims to explore the use of scientific and modern technologies in criminal investigation and how it helps to keep law and order in our society. It also discusses the problems in investigation, contemporary sciences and the essentialities of forensics in India.
Research Design in Adult Education: Issues and Perspectives
Authors: Fajimi Babatunde Ayoola
Published: March 2023

In the universities, students and researchers who engage in research writing have continued to find it difficult to understand the concept of research design, its importance and how to apply it in their project works at undergraduate and postgraduate levels. This may not be unconnected to the reasons most of them outsource the process of writing research projects to third parties with attendant consequences on the quality, validity and credibility of their research output. Research in Adult Education is aimed at proffering solutions to educational problems and creating new ideas in the field of education. This paper explored the concepts of research design and its significance in adult education research. The paper used documentary approach in qualitative research methodology to obtain secondary data from scholarly publications to examine the different approaches in design research and highlight the critical issues that students and researchers should acquaint themselves with in their pursuit to produce quality research projects.
INFLUENCE OF PHOSPHOGYPSUM ON THE RICE YIELD UNDER THE SALTED SOILS CONDITIONS OF THE KAZAKHSTAN ARAL REGION
Authors:   Kyzylorda University named after Korkyt Ata, Kyzylorda city, Republic of Kazakhstan, Tautenov I.A. , Bekzhanov S.Zh. ,   Kyzylorda University named after Korkyt Ata, Kyzylorda city, Republic of Kazakhstan, Abish N.T ,   Kyzylorda University named after Korkyt Ata, Kyzylorda, Republic of Kazakhstan, Zholdasbekkyzy N. ,   Kyzylorda University named after Korkyt Ata, Kyzylorda, Republic of Kazakhstan, Kultasov B.Sh. ,   Kyzylorda University named after Korkyt Ata, Kyzylorda, Republic of Kazakhstan
Published: March 2023

Қазақстандық Арал өңіріндегі Сырдария өзенінің төмеңгі ағысында күріш егуге арналған инженерлік жүйеге келтірілген суармалы жерлердің көлемі 270 мың гектардан асады. Қазіргі кезеңде топырақтардың тұздану, сортаңдану, сілтілену және мелиоративтік жағдайының нашарлануы себебінен бұрын игерілген күріш ауыспалы егістері жерлерінің шамамен 100 мың гектары пайдаланылмай отыр.Аймақтың тұзданған топырақтарын игеруде күріштің топырақ жақсартушы дақыл ретінде маңызды өте ерекше,себебі күріш атыздарынан шығатын қашыртқы сулармен суда еритін тұздар шайылып кетеді. Арал теңізінің құрғауы бұл аймақта экологиялық дағдарыс тудырды. Биологиялық және экологиялық тепе-теңдікті бұзып, нәтижесінде Сырдария өзені суының минералдануы жоғарылап, күріш жүйелері топырақтарының тұздануы артты. Егісті суару суының жетімсіздігіне байланысты дән өнімділігін ұдайы арттыру күріш шаруашылығының өзекті мәселесі болып табылады. Айтылған мәселеге байланысты күріш суару жүйесінің сортандаңған және сілтілі топырақтарында кальцийдің қорын молайту мақсатында химиялық мелиориант фосфогипстің әртүрлі дозалары зерттелініп, олардың күріш дақылының өнімділігіне әсері анықталды. Қазақстандық Арал өңірінің күріш жүйелерінің тұзданған топырақтарында фосфогипсті мелиорант ретінде пайдалану мүмкіндігі айқындалды.Фосфогипсті күріш өсімдігіне азоттың 120 кг/га фонында қолдану, бұл дақылдың өнімділігін тыңайтқышсыз бақылау нұсқасымен салыстырғанда, екі есеге дейін жоғарылатты. Фосфогипстің 5 т/га нормасын азоттың 120 кг/га фонында қолданғанда, күріш өнімділігі суперфосфатты 90 кг/га дозасында қолданған нұсқадан асып түсті, бұл тұзданған топырақтарда өсірілетін күрішке фосфогипсті фосфор тыңайтқышы ретінде қолдануға мүмкін болатынын көрсетті
EFFECT OF SUPPLEMENTARY FEEDING ON MILK PRODUCTION AND MILK CONTENT OF EWES OF KAZAKH FAT-TAILED SEMI-COARSE-WOOLED BREED
Authors:   S.Seifullin Kazakh Agro Technical University, Nur-Sultan,Republic of Kazakhstan, Ibrayev D.K. , Shauyenov S.K. ,   S.Seifullin Kazakh Agro Technical University, Nur-Sultan,Republic of Kazakhstan, Dolgasheva G.K. ,   S.Seifullin Kazakh Agro Technical University, Nur-Sultan,Republic of Kazakhstan, Muldasheva A.H. ,   S.Seifullin Kazakh Agro Technical University, Nur-Sultan,Republic of Kazakhstan, Mukhametzhanova I.E. ,   S.Seifullin Kazakh Agro Technical University, Nur-Sultan,Republic of Kazakhstan
Published: March 2023

Мақалада қазақтың ұяң жүнді құйрықты қойларының сүттілігі мен сүт құрамына қосымша азықтандырудың әсеріне арналған зерттеу нәтижелері келтірілген.Зерттеу нысаны ретінде Қарағанды облысы жағдайында өсірілетін қазақтың ұяң жүнді құйрықты қой тұқымының төрт жастағы саулықтары болды. Жалпы тәжірибеге 30 бас саулық, оның ішінде тәжірибелік топта 15 бас және бақылау тобына 15 бас аналог әдісімен алынған. Тәжірибедегі барлық саулықтар бір жағдайда жайылымда күтіп бағылған. Тәжірибелік топтағы саулықтарға қосымша азық ретінде экструдталған құрамажем тәулігіне бір басқа 300 г беріліп, ал бақылау тобына қосымша азықтар берілмеген. Зерттеу барысында тәжірибеге алынған саулықтар желіндерінің морфологиялық көрсеткіштері тәжірибенің басы мен соңында анықталып, лактацияның 105 күнінен бастап желін өлшемдерінің өзгерістері байқалған. Сауылған сүт мөлшері бойынша лактация басында саулықтардың орташа тәуліктік сауымы бақылау және тәжірибелік топтарына сәйкесінше 1380 және 1400 г құраса, ал тәжірибе соңында сәйкесінше 230 және 260 г болған, яғни зерттеуге алынған топтар бойынша тәжірибе тобының сүттілік көрсеткіші басым болғаны анықталған (P<0,05). Тәжірибедегі саулықтар сүтінің физика-химиялық құрамы бойынша қалыпты норма шегінде болды. Қосымша азықтандырылған саулықтардың сүтіндегі май мөлшері лактация соңына дейін тұрақты болатыны анықталды.
PHYTO-EXPERTIZE AND IMPROVEMENT OF SPRING WHEAT AND BARLEY SEEDS
Authors:   ", Kozhabayeva G.E. ,   Kazakh Scientific Research Institute of Plant Protection and Quarantine named after Zh.Zhiembayev",   , LLP, Almaty city, Republic of Kazakhstan, Kopirova G.I. ,   "Kazakh Scientific Research Institute of Plant Protection and Quarantine named after Zh.Zhiembayev", LLP, Almaty city, Republic of Kazakhstan, Baizhanova M.A. ,   "Kazakh Scientific Research Institute of Plant Protection and Quarantine named after Zh.Zhiembayev", LLP, Almaty city, Republic of Kazakhstan, Altay M.B ,   "Kazakh Scientific Research Institute of Plant Protection and Quarantine named after Zh.Zhiembayev", LLP, Almaty city, Republic of Kazakhstan, Usembayeva Zh.S. ,   "Kazakh Scientific Research Institute of Plant Protection and Quarantine named after Zh.Zhiembayev", LLP, Almaty city, Republic of Kazakhstan
Published: March 2023

В статье приведены данные лабораторных опытов по фитоэкспертизе и оздоровлению семян яровой пшеницы и ячменя. Своевременная фитоэкспертиза позволяет выявить спектр патогенов в семенных партиях, правильно выбрать протравитель для каждой конкретной партии семян в соответствии со спектром обнаруженных патогенов, повысить эффективность протравливания семян, добиться расширения спектра действия за счет добавления к химическим протравителям биопрепаратов, снизить затраты на протравливание за счет уменьшения дозировки протравителей и не допустить распространение опасных болезней. Наилучший показатель лабораторной всхожести на яровой пшенице и ячмене был выявлен в варианте Скарлет, м.э. (0,4 л/т) + Табу, в.с.к. (0,4 л/т) + Гумат калия (гуминовая кислота), ж., (1,0 л/т) – 99,3% и 98,0%, соответственно. Достаточно хорошие показатели были в вариантах Сид спор, ж.ф. (20,0 мл/т), Сид спор, ж.ф. (20,0 мл/т) + Селест топ, 312,5 к.с. (1,0 л/т), Пилигрим, к.с. (0,3 л/т) + Агрофлорин, ж. (20 мл/т) + Фомазин, ж. (3,0 л/т): на яровой пшенице энергия прорастания составила 96,9; 94,6 и 96,3%, соответственно. Наиболее эффективным и экономически выгодным по цене является вариант Скарлет, м.э. (0,4, л/т) + Табу, в.с.к. (0,4 л/т) + Гумат калия, ж. (1 л/т). Результаты опытов на питательной среде КГА в чашках Петри выявили наименьшее заражение семян пшеницы грибной микрофлорой в варианте Скарлет, м.э. (0,4 л/т) + Табу, в.с.к. (0,4 л/т) + Гумат калия, ж. (1,0 л/т) – 3,3%; на семянах ячменя – БисолбиСан, ж. (1,0 л/т) + Юнта, к.с. (1,75 л/т) + Фомазин, ж. (3,0 л/т) – 15,3%, в контрольном варианте – 100,0%. Таким образом, проведенные нами исследования по фитоэкспертизе и оздоровлению семян яровой пшеницы и ячменя выявили, что большинство испытанных защитно-стимулирующих составов положительно влияют на посевные качества семян и интенсивность роста проростков, а также эффективно подавляют грибную и бактериальную микрофлору семян пшеницы и ячменя и стимулируют развитие корневой системы.
INFLUENCE OF АPPLE DАMАGE WITH CАLIFORNIА SHIELD (QUАDRАSPIDIOTUS PERNICIOSUS) ON FRUITS QUАLITY АND THEIR SАFETY
Authors:   Kаzаkh Reseаrch Institute of Plаnt Protection аnd Quаrаntine nаmed аfter Zh.Zhiembаev Аlmаty city, Republic of Kаzаkhstаn, Kopzhаsаrov B.K , Beknаzаrovа Z.B. ,   Kаzаkh Reseаrch Institute of Plаnt Protection аnd Quаrаntine nаmed аfter Zh.Zhiembаev Аlmаty city, Republic of Kаzаkhstаn, Isinа Zh.M., ,   Kаzаkh Reseаrch Institute of Plаnt Protection аnd Quаrаntine nаmed аfter Zh.Zhiembаev Аlmаty city, Republic of Kаzаkhstаn, Dinаsilov А.S., ,   Kаzаkh Reseаrch Institute of Plаnt Protection аnd Quаrаntine nаmed аfter Zh.Zhiembаev Аlmаty city, Republic of Kаzаkhstаn, Kаldybekkyzy G., ,   Kаzаkh Reseаrch Institute of Plаnt Protection аnd Quаrаntine nаmed аfter Zh.Zhiembаev Аlmаty city, Republic of Kаzаkhstаn
Published: March 2023

Целью работы является снижение потерь урожая яблони при хранении. В статье приведены данные о влиянии повреждения калифорнийской щитовкой на качество урожая яблони. Калифорнийская щитовка является опасным вредителем плодовых культур, на эффективную защиту деревьев от нее, обеспечивающее снижение численности и получение товарного урожая, должны быть направлены усилия товаропроизводителей сельскохозяйственной продукции, что позволит исключить или снизить экономический ущерб. Вредитель относится к сосущим насекомым, её личинки прикрепляясь к коре дерева высасывают соки, отчего вокруг поврежденного места образуются неровности коры ствола и молодых побегов. На листьях появляются покраснения поврежденных участков, приводящие к их деформации, в результате чего они опадают. Более того, уменьшается общее количество зеленой массы и прирост деревьев, теряется качество плодов и их товарный вид. Яблоки, в сильной степени поврежденные щитовками, увядают быстрее, заболевают плодовой гнилью чаще, чем неповрежденные плоды, сроки хранения продукции значительно снижаются. Биологическая эффективность защитных мероприятий против калифорнийской щитовки составила 90,1-92,3%, одновременно уменьшив поврежденность плодов на 94,9-95,5%, повышение качества урожая снижало потери продукции при хранении с 15,5 % до 5-6%.
DIGITAL PROGRAM FOR THE USE OF PASTURE RESOURCES FOR GRAZING CATTLE
Authors:   Kazakh Research Institute of Livestock and Forage Production, Almaty city, Republic of Kazakhstan, Meldebekova N.A. , Kushenov K.I. ,   Kazakh Research Institute of Livestock and Forage Production, Almaty city, Republic of Kazakhstan, Shanbayev K.B. ,   Kazakh Research Institute of Livestock and Forage Production, Almaty city, Republic of Kazakhstan
Published: March 2023

В последние годы бессменное и бессистемное использование сказывается не только на деградации пастбищных угодий, но и в целом на развитии животноводства Казахстана.В результате этого площадь деградированных угодий постоянно увеличивается, а состояние используемых пастбищ не обеспечивает кормом потребность выпасаемого поголовья животных. Особенно остро сложилась ситуация на юго-востоке, юге и западе республики, где пастбищные земли вокруг населенных пунктов и открытых водных источников повсеместно сбиты. Потенциальная урожайность используемых пастбищ из-за перевыпаса скота снизилась до 50-60%. Предлагаемая цифровая программа поможетпастбищепользователям быстро рассчитать площадь пастбищ для нормированноговыпаса имеющегося в поголовья скота в зависимости от климатических условий года, фактическойурожайности пастбищной растительности и сезонных объемов кормозапасов пастбищных кормов и других факторов. На основе этих расчетов онможет принять правильные управленческие решения по организации сезонной ротации пастбищ, по оптимизации поголовья животных, продолжительность ихсодержания напастбищах, оставления части пастбищных земель на отдых и другие. Данная цифровая программа также окажет помощь работникам местных исполнительных органов и контролирующих органов сельских округов, районов и областей в проведении мониторинга соблюдения требований пастбищного законодательства в части рационального использования пастбищных ресурсов.
THE EFFECT OF FERTILIZERS ON THE QUALITY AND COMPOSITION OF PEANUT SEED GROWN IN TURKESTAN REGION
Authors:   Kazakh National Agrarian Research University, Almaty city, Republic of Kazakhstan, Muminova Sh.S. , Tastanbekova G.R. ,   Shymkent University, Shymkent, Republic of Kazakhstan, Balgabaev A.M. ,   Kazakh National Agrarian Research University, Almaty city, Republic of Kazakhstan, Raisov B.О. ,   Kazakh National Agrarian Research University, Almaty city, Republic of Kazakhstan
Published: March 2023

Қазіргі таңда елімізде өсімдік шаруашылығындағы құрылымдық және технологиялық әртараптандырудың нәтижесін байқауға болады. Мәселен бидайдың егістік ауданы қысқартылып, орнына майлы, мал азығы, жарма және бұршақты дақылдары егістігінің ауданы кеңейтілді. Демек, өсімдік шаруашылығы өнімдерінің өндірісі өсіп тұр. Оның бірі –майбұршақ. Майбұршақ – ертеден өсіріліп келе жатқан дақыл және ол дүниежүзілік маңызы бар басты мәдени өсімдіктер қатарына жатады. Майбұршақты негізінен таңғажайып өсімдік деп атайды. Себебі тұқымның құрамында жоғары мөлшерді ақуыз 33-тен 45%-ға дейін, 20-дан 25,7 % ға дейін май (оның кұрамында холестеролдың болмайтынын атап өткен жөн) және 25-21% көмірсулары бар. Еліміздің әртүрлі аймақтарының ғылыми мекемелерінде майбұршақты өсіру үшін нақты сенімді және жоғары өнімді сорттары өндірілуде. Оларды өсірудің интенсивті және бейімді аймақтық технологиялары әзірленді, олар жоғары өнім алудың негізі болып табылады. Осы облыстарда майбұршақ дақылын табысты өсіруде көп жылғы озық тәжірибенің байлығы жинақталған. Дегенмен, барлық аймақтарда майбұршақтың тұрақты жоғары өнімін алу үшін белгілі бір жағдайларды ескере отырып, сенімді сорттар мен оларды өсіру әдістерін таңдаудың заманауи ғылыми негізделген аграрлық талаптарын қатаң сақтау қажет. Бұл мақалада әр түрлі минералды тыңайтқыштардың, микроэлементтер мен өсу стимуляторларының майбұршақ дәнінің сапасына әсері бойынша далалық тәжірибелердің нәтижелері берілген. Ғылыми-зерттеу жұмыстары «Оңтүстік-Батыс мал шаруашылығы және өсімдік шаруашылығы ғылыми-зерттеу институты» ЖШС тәжірибе алаңында жүргізілді. Ласточка сортында фосфорлы-калийлі тыңайтқыштарды және «әмбебап Вуксал» өсу стимуляторын қолданудың тиімділігі Ласточка сортында 5,08 % құрайтыны анықталды, бұл бақылаудағыдан 0,11 % жоғары көрсеткішті көрсетті. Ал, Аққу сортында 4,88 %, Галина сортында 4,82% бұл бақылауға қарағанда 0,20% және 0,28% төмен көрсеткішті көрсетті. Фосфорлы-калийлі тыңайтқыштар мен өсу стимуляторларын қолдану майбұршақ тұқымындағы майлылыққа оң әсерін тигізді. Осылайша, NPK + Эпин қолдану нұсқасында Ласточка сортының тұқымындағы май мөлшері 25,53% құрады; Аққу сорты – 24,62%; Галина сортында – 26,01%, бақылаудағы майбұршақтан 4,26-ға артық, керісінше 1,99 және 3,64% көреткішті көрсетті
TERMSFOR CREATION OF FOREST CROPS OF BLACK SAXAUL (HALOXYLON APHYLLUM) IN WEST KAZAKHSTAN
Authors:   Almatybranch of Kazakh Scientific Research Institute of Forestry and Agroforestry named after A.N. Bukeikhan LLP, Almaty city, Republic of Kazakhstan, Akhmetov R.S. , Mambetov B.T. ,   Kazakh National Agrarian Research University, Almaty city, Republic of Kazakhstan, Kentbaev E.Zh. ,   Kazakh National Agrarian Research University, Almaty city, Republic of Kazakhstan, Dosmanbetov D.А. ,   Almatybranch of Kazakh Scientific Research Institute of Forestry and Agroforestry named after A.N. Bukeikhan LLP, Almaty city, Republic of Kazakhstan, Yesimbek B.B. ,   Kazakh National Academy of Art named after T.Zhurgenov, Almaty city, Republic of Kazakhstan
Published: March 2023

The authors of the article, on the basis of studies conducted on the territory of the state forest fund of the KSU "Samsk State Institution for the Forests and Wildlife Protection" of the Department of Natural Resources and Environmental Management in Mangystau Region, prove that in the arid conditions of Western Kazakhstan, the terms of planting black saxaul affects growth and survival rate. The main indicator of the success of silvicultural work is the survival rate and growth, which more fully characterize the physiological state of plants in connection with transplantation. The survival rate of seedlings is closely related to the amount of soil moisture at the time of planting and in the first 10-15 days after it. The article presents the results of the optimal terms of the creation of black saxaul crops in spring. The most reliable way to create forest saxaul crops is spring planting with annual standard seedlings, which ensures a high percentage of survival rate and distribution of plants over the entire area compared to autumn sowing. Preliminarily, the first ten days of April should be considered the optimal planting time for the arid conditions of Western Kazakhstan. Delay in forest planting by one decade significantly reduces the survival rate of crops.
OBTAINING DRY BIOMASS OF THE DRUG BASED ON THE YEAST STRAIN METSCHNIKOWIA PULCHERRIMA MP-3
Authors:   RSE on REM ", Satenova A.M. ,   Republican Collection of Microorganisms",   MHRK, Astana city, Republic of Kazakhstan, Tuyakova A.K. ,   RSE on REM "Republican Collection of Microorganisms" MHRK, Astana city, Republic of Kazakhstan, Urazova M.S. ,   RSE on REM "Republican Collection of Microorganisms" MHRK, Astana city, Republic of Kazakhstan, Abilkhadirov A.M. ,   RSE on REM "Republican Collection of Microorganisms" MHRK, Astana city, Republic of Kazakhstan, Shaikhin S.M. ,   RSE on REM "Republican Collection of Microorganisms" MHRK, Astana city, Republic of Kazakhstan
Published: March 2023

Дрожжи, активно участвующие в биологических процессах окружающей среды и являющиеся продуцентами многих соединений, необходимых человеку, остаются популярным объектом изучения в различных научных направлениях – биологии, микробной экологии, генетики, биотехнологии. Одним из современных направлений является использование дрожжей как средств биоконтроля в борьбе с послеуборочными патогенами плодовых культур. Европейское агентство по безопасности пищевых продуктов (EFSA) официально признало средствами защиты растений от грибковых заболеваний некоторые штаммы дрожжей Metschnikowia. Целью данной работы являлся подбор оптимальных условии культивировании и режимов лиофильной сушки для получения сухой формы биопрепарата на основе дрожжевого штамма. Проведен сравнительный анализ показателей жизнеспособности в двух экспериментах с использованием различных условий культивирования штамма и режимов лиофилизации. По результатам проведенных экспериментов были подобраны среды показавшие высокие результаты по накоплению биомассы - среда Риддера с солодовой средой 1:1, в качестве защитной среды показал хороший результат - обезжиренное молоко. Также был подобран оптимальный режим лиофилизации для получения сухого биопрепарата на основе штамма дрожжей Metschnikowiapulcherrima МР-8. Жизнеспособность после лиофилизации при подобранных режимах показал - 2,4×1010 КОЕ/мл, жизнеспособность после 6 месяцев хранения (4 °С) показал - 2,3×109 . Штамм дрожжей Metschnikowiapulcherrima МР-8 был ранее выделен нами с поверхности груши сорта «Талгарская красавица» (Алматинская область) и является антагонистом целого ряда плесневых грибов: Alternaria alternata, Penicillium expansum, Acremonium alternatum. Применение бактерий-антагонистов, подавляющих рост микробов послеуборочной порчи и гниения является одним из наиболее безопасных методов обработки плодов
The Comparative Effectiveness of Botulinum Toxin-A Injection Therapy Versus Augmentation Uretero-Enterocystoplasty for the Treatment of Lower Urinary Tract Dysfunction
Authors: Wang Xuesheng , Zhou Zhonghan , Liao Limin
Published: March 2023

Purpose: We investigated the effectiveness of intravesical botulinum toxin-A (BTX-A) injection therapy in patients with lower urinary tract dysfunction (LUTD) and upper urinary tract (UUT) deterioration and evaluated whether BTX-A injection therapy could substitute for augmentation uretero-enterocystoplasty (AUEC).Methods: Data from a prospective, single-center cohort from 2017–2021 were analyzed. Patients were divided into 2 treatment groups: AUEC and BTX-A (i.e., patients who declined AUEC). Bladder and UUT functions were assessed by comparing clinical information, urodynamic data, laboratory results, and imaging records.Results: In total, 121 patients were enrolled (BTX-A group: 41 patients; AUEC group: 80 patients). The BTX-A group showed a reduced maximum detrusor pressure and increases in the maximum bladder volume and bladder compliance (P<0.05). However, in follow-up evaluations, significantly smaller improvements (all P<0.05) in urodynamic parameters were found in the BTX-A group than in the AUEC group. Notably, there was no significant improvement in vesicoureteral reflux (VUR; P=0.66) or upper urinary tract dilatation (UUTD; P=0.75) in the BTX-A group, and no statistically significant difference in serum creatinine (Scr) levels or the estimated glomerular filtration rate (eGFR) was observed in the follow-up evaluations (all P>0.05). Both VUR and UUTD improved significantly in the AUEC group, and the Scr and eGFR levels significantly improved after AUEC relative to baseline levels (P<0.05). The reduction in the Scr level was significantly lower in the BTX-A group than in the AUEC group during 0–15 months of follow-up (Scr reduction differences, -1.36; P<0.01).Conclusions: Although BTX-A injection therapy was effective for improving bladder function, BTX-A injections did not alleviate UUT deterioration in this study, particularly in patients with advanced-stage LUTD. Conversely, AUEC for LUTD has a well-established role in improving UUT function. Hence, BTX-A injection therapy should not replace AUEC to ameliorate UUT impairment and protect UUT function.
Effects of Age and Multiple Vaginal Births on Lower Urinary Tract Structure and Function in Nonhuman Primates
Authors: Williams J. Koudy , Andersson Karl-Erik , Lankford Shannon , Badlani Gopal
Published: March 2023

Purpose: The relative roles of urinary sphincter damage, aging, and childbirth in stress urinary incontinence (SUI), have not been established. This study was performed to elucidate the roles of these factors.Methods: The study included: (1) 8 female cynomolgus monkeys (17–19 years of age and 7–8 vaginal births each); (2) six 5-yearold nulliparous monkeys with surgically created chronic urinary sphincter dysfunction; and (3) six 5-year-old, nulliparous, nosurgery controls. Sedated abdominal leak point pressure (ALPP) and maximum urethral sphincter pressures (MUP) were measured. Sphincters, bladders, and pelvic support muscles were quantified for collagen content. Additionally, bladders were analyzed for collagen fiber thickness, length, and angle using CT-FIRE analysis of Picrosirius red-stained tissues.Results: Resting MUP values were similar in the controls and older multiparous monkeys (P>0.05). However, aging and multiple births reduced pudendal nerve-stimulated increases in MUP (P<0.05 vs. controls). ALPP values were lower in the older multiparous versus younger groups of monkeys (P<0.05). Sphincter collagen content was greater, and muscle content less, in the injury model (P<0.05 vs. controls). However, these measures were not affected by age and childbirth (P>0.05 vs. young groups). Bladder collagen content was greater, and muscle content less, in the old multiparous monkeys (P<0.05 vs. younger groups). Additionally, collagen fibers were thicker and more angular in the bladders of the older multiparous monkeys than in the other nonhuman primate groups (P<0.05). Pelvic support muscles had higher collagen and lower muscle content in the older multiparous monkeys than in the younger groups of monkeys (P<0.05).Conclusions: SUI, associated with aging and multiple childbirths, appeared to be more strongly associated with bladder dysfunction, reduced pelvic muscle support, and the compensatory response to neural stimulation than with selective urinary sphincter dysfunction.
Development and Evaluation of Urolithiasis Detection Technology Based on a Multimethod Algorithm
Authors: Park Jong Mok , Eun Sung-Jong , Na Yong Gil
Published: March 2023

Purpose: In this paper, we propose an optimal ureter stone detection model utilizing multiple artificial intelligence technologies. Specifically, the proposed model of urinary tract stone detection merges an artificial intelligence model and an image processing model, resulting in a multimethod approach.Methods: We propose an optimal urinary tract stone detection algorithm based on artificial intelligence technology. This method was intended to increase the accuracy of urinary tract stone detection by combining deep learning technology (Fast R-CNN) and image processing technology (Watershed).Results: As a result of deriving the confusion matrix, the sensitivity and specificity of urinary tract stone detection were calculated to be 0.90 and 0.91, and the accuracy for their position was 0.84. This value was higher than 0.8, which is the standard for accuracy. This finding confirmed that accurate guidance to the stones area was possible when the developed platform was used to support actual surgery.Conclusions: The performance evaluation of the method proposed herein indicated that it can effectively play an auxiliary role in diagnostic decision-making with a clinically acceptable range of safety. In particular, in the case of ambush stones or urinary stones accompanying ureter polyps, the value that could be obtained through combination therapy based on diagnostic assistance could be evaluated.
Anna Triandafyllidou and Tariq Modood (eds), The Problem of Religious Diversity: European Challenges and Asian Approaches; Edinburgh University Press, Edinburgh, 2017, $53.61 (Paperback), pp. 352, ISBN 9781474419093
Authors: KONNEH Karamo Faruk
Published: March 2023

Religion and religious diversity are two of the most critical aspects of European diversity today. Older models of republicanism and multiculturalism appear to be in crisis, but no new “third route” between laicité and state religion is emerging.
Intracellular transport by motor proteins with the same directionality
Authors: Xie Kewei , Wang Qian ,   Department of Physics, University of Science and Technology of China, Hefei 230026, China
Published: March 2023

Active intracellular transport is mainly performed by a group of special nanomachines called motor proteins. During transport, cooperation between motor proteins significantly influences important transport features, such as distance and velocity. To understand this mechanism, we combine Gillespie simulation and analytical derivation to demonstrate how the mechanical properties of a single motor influence the cooperation between multiple motors, further regulating the transport distance. In addition, we build a deep learning model to help us quickly obtain the motor parameters. Our results shed light on the physical nature of intracellular transport by motor proteins with the same directionality.
A sustainable inventory model for growing items considering carbon emissions, product expiry, and profit-sharing policy
Authors: Chandramohan Jayasankari , Ramasamy Uthayakumar
Published: March 2023

In this article, a multi-echelon supply chain for growing and deteriorating items, where the grower has a lot of live newborn items (growing) is discussed. The grower transfers the matured inventory to the processor in each shipment. The processor begins to process the stock as a ready-sale product in the market. The processor also delivers the processed inventory to the retailer in each shipment in the non-processing period of his cycle length. Then the processor offers trade credit to the retailer and makes the retailer agree to share a portion of his profit with him. The product’s life cycle when in the hand of the retailer is certain and it expires after some time t. Carbon emission during processing is considered while packing and preserving the livestock for sale. Depending on these assumptions, there are six possibilities to discuss profit values. Sensitivity analysis was also brought to verify the optimal determined values. The profit-sharing sharing method’s outcome benefits the processor and the retailer more.
Tạp chí Nghiên cứu Y học tập 100 (2) 2016
Authors: Nghiên cứu Y học Tạp chí
Published: March 2023

Toàn văn Tạp chí Nghiên cứu Y học tập 100 (2) 2016
Pulmonary manifestations of Granulomatosis with Polyangiitis (GPA)
Authors:   Senior Clinical Fellow, Respiratory Medicine, Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, Cheshire, SK2 7JE, Sseguya Paul , Arangelova Svetlana ,   Consultant Acute Physician, Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, Cheshire, SK2 7JE, Bhatia Praveen ,   Consultant Respiratory & General Physician, Stepping Hill Hospital, Stockport, UK, Bucur Anca ,   Senior Clinical Fellow, Respiratory Medicine, Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, Cheshire, SK2 7JE
Published: March 2023

Granulomatosis with Polyangiitis is a rare multisystem autoimmune disease-causing inflammation of blood cells in the lungs, the sinuses, throat, kidneys, and the nervous system. People most affected are Caucasians, with age of occurrence 40 to 60ysrs. Among genetically susceptible individuals, Bacterial and viral infections initiate autoantibody production that interacts with immune cells, adhering to epithelial membranes and causing destruction. The illness involves the upper rasp tract in > 90% of cases but the inflammatory process can also involve the rest of the pulmonary system, the orbit, the heart, renal system, and adrenal system. The patients can present to any of the clinical specialties. Management is usually immunosuppression and supportive care
Ground Glass Changes on CT, causes and management
Authors:   Consultant Radiologist, Tameside General Hospital, Fountain Street, Ashton-Under-Lyne, OL6 9 RW, Musda William , Arangelova Svetlana ,   Consultant Acute Physician, Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, Cheshire, SK2 7JE, Sseguya Paul ,   Senior Clinical Fellow, Respiratory Medicine, Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, Cheshire, SK2 7JE, Bucur Anca ,   Senior Clinical Fellow, Respiratory Medicine, Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, Cheshire, SK2 7JE
Published: March 2023

Ground Glass (GG) changes can be normally seen on a CT thorax if done during expiration. However, various conditions, both malignant and benign, may also present as GG changes. The typical radiological manifestation of Covid pneumonitis is ground glass changes, and in this short review, we will look at other causes of ground glass changes on the CT thorax. These are usually non-specific, but knowledge of the causes of GG changes can help the respiratory physician plan further tests and reach a diagnosis.
How to assess a patient with breathlessness
Authors:   Junior Clinical Fellow, Respiratory Medicine, Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, Cheshire, SK2 7JE, Radhakrishnan Gowri , Arangelova Svetlana ,   Consultant Acute Physician, Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, Cheshire, SK2 7JE, Sseguya Paul ,   Senior Clinical Fellow, Respiratory Medicine, Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, Cheshire, SK2 7JE
Published: March 2023

This article is aimed to guide Junior doctors in the assessment and initial management of a patient presenting with breathlessness – a presentation very commonly seen in the wards and the emergency department. This article outlines the most common causes of breathlessness in adults and what to look for on examining the patient. It also elaborates on the preliminary investigations required to make a diagnosis and the initial treatment that can be administered at the level of a Junior doctor.
A Case of Unusual Oral Theophylline Toxicity
Authors:   Senior Clinical Fellow, Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, Cheshire, SK2 7JE, Makstutis Simonas
Published: March 2023

Theophylline is a methylxanthine medicine used for treatment of bronchospasm in asthma and COPD. This reports illustrates a case where a patient was taking oral theophylline for COPD, was admitted to hospital with confirmed COVID-19 and subsequently developed a combination of vague signs, symptoms and biochemistry results, such as confusion, sinus tachycardia, compensated metabolic acidosis, hypomagnesaemia and refractory hypokalaemia. These non-specific signs and symptoms were initially attributed to other causes such as infection; however subsequent review of the patient’s medication suggested that theophylline toxicity could be the cause. These non-specific signs and symptoms were present despite normal plasma aminophylline level and resolved once treatment with oral theophylline was ceased.
A lady with breathlessness
Authors:   Consultant Acute Physician, Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, Cheshire, SK2 7JE, Arangelova Svetlana , Umate Anil ,   Trust Registrar, Tameside General hospital, Fountain Street, Ashton-Under-Lyne, OL6 9RW
Published: March 2023

A 55-year-old lady presented to hospital with increasing breathlessness for 2 days and a cough with green phlegm, but no other chest symptoms. She had a past medical history of COPD, was an ex-smoker, CKD 3, and some cardiac surgery in her childhood. Had recurrent admissions for dyspnoea and type 2 respiratory failure, needing NIV on each admission. She mentioned that she’s never been a heavy smoker, stopped smoking more than 10 years back. Her only medication was a PRN Salbutamol inhaler.
Management of Subcutaneous Emphysema associated with Pneumothorax: a case report and review of literature
Authors:   Consultant Acute Physician, Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, Cheshire, SK2 7JE, Arangelova Svetlana , Sseguya Paul ,   Senior Clinical Fellow, Respiratory Medicine, Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, Cheshire, SK2 7JE, Bucur Anca ,   Senior Clinical Fellow, Respiratory Medicine, Stepping Hill Hospital, Poplar Grove, Hazel Grove, Stockport, Cheshire, SK2 7JE, Bhatia Praveen ,   Consultant Respiratory & General Physician, Stepping Hill Hospital, Stockport, UK
Published: March 2023

Subcutaneous Emphysema is usually a benign, self-limiting condition that has various causes. It can be quite distressing due to the facial swelling associated with it. If associated with pneumothorax, it can be effectively managed by large bore chest drain with or without suction. Though subcutaneous incisions and subcutaneous drains have been used to treat it, most patients improve with chest drain and suction. We present a case report of Surgical emphysema that was successfully managed and review the relevant literature.
Aspectos bioéticos do manejo pericial de óbitos por COVID-19
Authors: Barbosa Felipe Romério
Published: March 2023

A pandemia do novo coronavírus (SARS-CoV-2) trouxe à tona questionamentos bioéticos e desafios no manejo dos falecidos pela doença. Dentro dessa perspectiva, faz-se necessário avaliar por meio dos pontos elencados dentro do presente artigo, como tais questionamentos podem colaborar para a Medicina Legal no tocante aos preceitos éticos, jurídicas e técnico-científicos. O presente artigo de Ponto de Vista aborda, com sólido e atualizado embasamento científico, o que se sabe até o momento sobre os mecanismos de transmissão do novo coronavírus e os meios disponíveis para evitar a sua disseminação, além de melhor esclarecer os protocolos e diretrizes utilizadas, auxiliando os serviços funerários e de saúde.
PENURUNAN KADAR BESI (Fe) DENGAN SISTEM AERASI DAN FILTRASI PADA AIR SUMUR GALI
Authors: Amiliza Miarti
Published: March 2023

Pengadaan air bersih di Indonesia khususnya untuk skala yang besar masih terpusat didaerah perkotaan, dan dikelola oleh Perusahaan Air Minum (PAM) kota yang bersangkutan. Namun demikian secara nasional jumlahnya masih relatif kecil dan dapat dikatakan belum mencukupi.

Penelitian ini bertujuan untuk mengetahui penurunan kadar besi (Fe) dengan sistem aerasi dan filtrasi pada air sumur gali. Penelitian untuk mengetahui kadar besi dengan sistem aerasi dan filtrasi pada air sumur gali dengan desain pre-pos Test atau melakukan uji pada air baku dan air hasil pengolahan. Dalam proses penelitian akan dilakukan replikasi atau pengulangan proses pengolahan hingga media filter mencapai titik jenuh.

Penurunan kadar besi (Fe) setelah perlakuan Aerasi dapat menurunkan kadar besi (Fe) hingga mencapai persentase Penurunan sebesar 66,7%. Dan hasil yang diperoleh telah sesuai persyaratan yang telah di tentukan sesuai Permenkes RI No. 416/MENKES/PER/IX/1990, yaitu 1.0 mg/l.
The recursive and causative correlations for viability of the third way of development of the Amazon
Authors: Barbosa Marcelo Augusto Mendes , Moret Artur de Souza , Nantes Rosalina Alves
Published: March 2023

The conceptions of development implemented and experimented within the Brazilian Amazon weren’t inclusive, not being solidifying in socioeconomically long term. The Amazon urges for development that advocates the inclusion of the full exercise of civil, political and civic rights; in sustainability that are conceived in the long term, susceptible to continuity, without exhausting, in parts or in full, the biome that sustains it. This article aims to find the correlation and recursive causality between the discourse of the third way of development and it’s variables: environmental, economic and social, which will be the object of an analysis towards a new paradigm of development in the Amazon. To organize the collected data, Libault's (1971) methodology will be applied, which organizes the data into four distinct stages: compilation, correlation, semantics and normative process. Also considering the need to create a recursive relationship between the results of the variables, we developed a matrix that portrays the recursive and causal process of the variables: Economic, Environmental and Social. Facing the analyses, we obtain results which indicate that in the process there is causality and recursion in the third way, considering that there is a correlation between the terms: Amazon, biodiversity, value, products and economy.
Gestión directiva del currículo
Authors: Arroyo Valenciano Juan Antonio
Published: March 2023

En este artículo, el autor destaca la relevancia que tiene para la Gestión Directiva del Currículo, la identificación de la visión de sociedad y ser social a la que aspira cada comunidad política. Una vez esa visión está claramente identificada, sostiene el autor, la gestión directiva del currículo asume la tarea de identificar y proponer estrategias, acciones y mecanismos, juntamente con cuerpo docente y administrativo, para que en función de esa visión se realice y oriente todo el esfuerzo educativo.
Chemogenomics: Is A Promising Area for Drug Target and Discovery
Authors:   Department of Pharmaceutical Chemistry, K. K. Wagh College of Pharmacy, Nasik, Maharashatra, India, Amrutkar Rakesh Devidas , Bhamare Vaibhav G ,   Department of Pharmaceutics, K. K. Wagh College of Pharmacy, Nasik, Maharashatra, India, Kapse Sachin N ,   Department of Pharmaceutical Chemistry, Matoshri College of Pharmacy, Nasik, Maharashatra, India
Published: March 2023

The latest tools of genomics and chemistry and applies them to target and drug discovery is chemogenomoics. It is defined as the analysis of class of organic compound libraries against families of functionally related proteins called as receptor. chemogenomoics help to investigate biological target for the new drug entities. This deals with the systematic investigation of chemical-biological interactions. Study of chemogenomoics is the very important tool in medicinal chemistry for the development of new chemical entities) The main goal of chemogenomics is to identify the newer drugs and the targets because of number of chemical entities ware present so it is very difficult to identify the targets of said chemical compounds. The chemogenomic approach is the interaction of possible drug molecules with all probable targets In this regards we have reported significance and application of chemogenomoics.
Improving Buyer-supplier Relationships: A Supplier's Perspective
Authors: Scheerlinck Glenn , Reniers Genserik , Michiels Hans
Published: March 2023

Background: Literature review shows there are very few studies looking at the buyer-supplier relationship from the supplier’s perspective. Furthermore, the available studies are largely qualitative research. This gap in quantitative literature leads us to question which and to what extend certain variables influence the preferred customer status from a supplier’s viewpoint. Based on a qualitative literature review, nine variables should be considered in explaining preferred customer status. Objective: This study attempts to find quantitative scientific evidence for variables that can improve buyer-supplier relationships. Methods: The study utilises a supplier survey. Supplier contact details are extracts from the Enterprise Resource Planning software of two production sites within a business division of a large cap multinational healthcare company noted on the SIX Swiss Exchange. In total 2.737 online surveys were sent out and 319 answers received. These answers serve as data to build a multiple linear regression model. Results: The results indicate that the variables explain 41% of the variance (R2adj) of preferred customer status. Our research supports the idea that preferred customer status is significantly influenced by financial attractiveness, corporate social responsibility (CSR), and proximity. The findings suggest that both financial attractiveness and CSR have a positive partial effect on preferred customer status that is diminishing as the independent variables keep increasing, while the positive effect from proximity on preferred customer status is linear. Conclusion: Buyers should be aware of the significance that these three variables hold on their preferred customer status, from a supplier’s viewpoint. Buyers should carefully consider the potential effects of their decisions regarding the generation of sufficient and steady cash flow at the supplier, the risk of an undersized CSR policy, and the value of proximity in a supply chain.
Penerapan Prinsip 5C pada Layanan Simpan Pinjam L-Smart BUMDes Bumiayu Kanaka Pringsewu Provinsi Lampung
Authors: Arizal Muhammad , Hasnawati Sri , Hendrawaty Ernie , Marvinita Risda , Fathia Syaharani Noer
Published: March 2023

Badan Usaha Milik Desa (BUMDes) Bumiayu Kanaka, Kabupaten Pringsewu Provinsi Lampung bergerak pada bidang perdagangan, peminjaman modal usaha L-Smart, dan agen BNI 46. Layanan Simpan Pinjam L-Smart bekerjasama dengan Bank Lampung bertujuan untuk memajukan kesejahteraan masyarakat dengan menyediakan peminjaman kepada nasabah. Namun kegiatan ini mengalamai penurunan nasabah seiring berjalannya waktu karena penundaan pembayaran hutang oleh nasabah. Hal ini mengakibatkan kerugian pada pengurangan modal untuk unit usaha L-Smart. Atas permasalahan ini maka perlu dilakukan analisis analisis efektivitas terhadap penerapan layanan simpan pinjam L-Smart BUMDes Bumiayu Kanaka dengan prinsip 5C. Metode yang digunakan dalam penelitian ini yaitu pendekatan kualitatif menggunakan teknik wawancara, observasi, studi kepustakaan, dan dokumentasi. Hasil pada studi ini adalah analisis 5C dalam kelayakan peminjaman dana BUMDes Bumiayu Kanaka belum sepenuhnya baik dilaksanakan karena tidak menganalisis Capital dan Condition. Selanjutnya disarankan untuk keberlanjutan unit usaha tersebut untuk BUmdes Bumiayu Kanaka kebih selektif dan professional dalam memilih calon debitur.
Random Numbers Generation and Goodness-of-Fit Testing for Literal Neutrosophic Numbers
Authors:   Faculty of Science, Department of Mathematical Statistics, University of Aleppo, Aleppo, Syria, Zeina Mohamed Bisher ,   Faculty of Science, Department of Mathematical Statistics, University of Aleppo, Aleppo, Syria,   Faculty of Science, Department of Mathematical Statistics, University of Aleppo, Aleppo, Syria, Anan Mohamad Taher , Marjamak Yousef
Published: March 2023

This paper presents an algorithm for generating random numbers that follow literal neutrosophic distributions using algebraic isomorphisms. The algorithm was applied to three distributions: literal neutrosophic uniform distribution, literal neutrosophic exponential distribution, and literal neutrosophic normal distribution. We also proposed a development of the Kolmogorov-Smirnov test to analyze goodness-of-fit for literal neutrosophic data. To evaluate the effectiveness of the proposed method, a simulation study was conducted, and the power results showed that increasing the sample size improved the test power. Our research contributes to the development of statistical methods for analyzing literal neutrosophic data, which has applications in a wide range of fields.