bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Pembelajaran Menggunakan Media Pembelajaran Interaktif terhadap Hasil Belajar siswa di Sekolah Dasar
Authors: Harsiwi Udi Budi , Arini Liss Dyah Dewi
Published: January 2021

Latar belakang penelitian ini adalah salah satu faktor yang mempengaruhi kemajuan bangsa adalah kualitas sumber daya manusia dalam menguasai pengetahuan dan teknologi di era revolusi industri 4.0. Kualitas pendidikan semakin dituntut untuk meningkat agar dapat mengikuti perkembangan zaman yang berkembang dengan sangat pesat. Media pembelajaran juga merupakan dasar yang sangat diperlukan demi berhasilnya proses pembelajaran. Tujuan penelitian ini adalah (1) mengembangkan media pembelajaran berbasis adobe flash; (2) menganalisis perbedaan motivasi antara siswa yang menggunakan media adobe flash dan konvensional; (3) menganalisis perbedaan hasil belajar antara siswa yang menggunakan media adobe flash dan konvensional; (4) menganalisis perbedaan motivasi dan hasil belajar antara siswa yang belajar IPA menggunakan media adobe flash dan konvensional di SD N 06 dan 07 Ngringo, Karanganyar. Tahapan metode penelitian ini adalah penelitian eksperimen dengan rancangan postest only control group design. Subjek penelitian ini adalah siswa kelas V di SDN 06 dan 07 Ngringo, Karanganyar. Pengambilan kelas penelitian melalui teknik random sampling berdasarkan. Kegiatan dalam analisis data meliputi pengolahan data dan analisis statistik. Kesimpulan penelitian ini adalah secara umum model pembelajaran melalui media pembelajaran interaktif (video swf) dapat memotivasi siswa sehingga dapat meningkatkan prestasi belajar mahasiswa. Siswa memberikan respon positif terhadap implementasi model pembelajaran interaktif (video swf).
Pengaruh Asupan Nutrisi Shake Kacang Kedelai terhadap Skala Lemak Perut Guru-guru Sekolah Dasar di Bangkinang Kota Kabupaten Kampar
Authors: Witarsa Ramdhan , Fadhilaturrahmi Fadhilaturrahmi , Rizal Muhammad Syahrul
Published: January 2021

Permasalahan penelitian yang melatarbelakangi penelitian ini adalah banyaknya guru-guru sekolah dasar yang memiliki kelebihan berat badan dan perut yang buncit. Hal ini dikarenakan skala lemak perut tinggi yang dimiliki hampir sebagian besar guru-guru sekolah dasar di Bangkinang Kota, Kabupaten Kampar. Tingginya skala lemak perut tersebut dikarenakan kurangnya berolahraga dan asupan nutrisi yang salah. Tujuan penelitian ini ingin melihat pengaruh asupan nutrisi shake kacang kedelai yang dipercaya sebagai rendah kalori namun berenergi tinggi terhadap skala lemak perut guru-guru. Metode Penelitian yang digunakan adalah kuasi eksperimen. Jumlah sampel sebanyak 20 orang guru. Hasil penelitian menunjukkan bahwa dengan pemberian asupan nutrisi shake kacang kedelai selama satu bulan secara signifikan menurunkan skala lemak perut dari kategori bahaya ke kategori tinggi (80%) dan semakin bugarnya fisik guru-guru yang diteliti. Kebaruan penelitian ini adalah adanya peningkatan skala kesehatan guru-guru serta cara dan gaya hidup sehat. Dampak dan impak dari hasil penelitian ini adalah cara dan gaya hidup sehat yang dijalanin selama program dilanjutkan oleh guru-guru tersebut di lingkungan kelas dan lingkungan keluarganya
Pengembangan Perangkat Pembelajaran Matematika Berbasis Kompetensi 4K Anies Baswedan dan Multiple Intelligences
Authors: Rulyansah Afib , Wardana Ludfi Arya
Published: January 2021

Keterampilan-keterampilan yang harus dimiliki oleh peserta didik juga memerlukan kecerdasan yang sesuai dengan kompetensi yang dimiliki, terutama pada pembelajaran matematika sering kali tidak disukai siswa. Pengembangan perangkat pembelajaran perlu dilakukan agar dapat menghasilkan perangkat pembelajaran matematika yang valid, praktis, menarik dan efektif. Jenis penelitian yang dilakukan adalah penelitian dan pengembangan atau yang sering disebut Research and Development (R&D). Model pengembangan pada penelitian ini diadaptasi dari ADDIE yang berbasis pada Multiple Intelligences dan Kompetensi 4K Anies Baswedan. Berdasarkan hasil penilaian validasi dari ahli desain pembelajaran menunjukkan rata-rata 4,8 dengan presentase 96%. Ahli materi dan LKS menunjukkan rata-rata 5 dengan presentase 100%. Hasil ahli perangkat pembelajaran matematika kelas V yang didapat menunjukkan nilai rata-rata 4,7 dengan persentase 95%. Respon siswa terhadap learning media matematika berbasis kompetensi 4K Anies Baswedan dan Multiple Intelligence yang dikembangkan menunjukkan hasil persentase rata-rata diatas 85% yang berarti sebagian besar siswa memberikan respon positif atau sangat kuat. Berdasarkan temuan hasil penelitian dapat dikatakan bahwa perangkat pembelajaran matematika berbasis kompetensi 4K Anies Baswedan dan Multiple Intelligence sangat praktis, efektif dan menarik dalam proses belajar dikelas dengan persentase 98%
Pengaruh Kemampuan Berpikir Kreatif untuk meningkatkan Hasil Belajar Matematika di Sekolah Dasar
Authors: Manurung Alberth Supriyanto , Halim Abdul , Rosyid Ainur
Published: January 2021

Tujuan penelitian ini adalah untuk menentukan Pengaruh Kemampuan Berpikir Kreatif untuk meningkatkan Hasil Belajar Matematika Siswa kelas V SD. Metode penelitian yang digunakan adalah metode survei dan mengunakan teknik analisis regresi dan korelasi sederhana, regresi dan korelasi ganda. Penelitian ini dilakukan di SDN Kenari 07 Pagi Jakarta, kecamatan Salemba, Jakarta Pusat dengan n = 36 dengan menggunakan teknik Cluster Sampling.Penelitian ini dilandasi dengan hipotesis-hipotesis sebagai berikut : (1) Kemampuan Berpikir Kreatif memiliki pengaruh terhadap hasil belajar matematika; (2) Minat memiliki pengaruh terhadap Kemampuan Berpikir Kreatif; (3) Latar belakang siswa memiliki pengaruh Kemampuan Berpikir Kreatif; (4) Intelegensia memiliki pengaruh Kemampuan Berpikir Kreatif; (5) Terdapat pengaruh antara bakat dan Kemampuan Berpikir Kreatif dengan hasil belajar matematika. Berdasarkan penelitian ini diharapkan hasil belajar matematika siswa kelas V SD dapat ditingkatkan dengan pengaruh Kemampuan Berpikir Kreatif, karena hasil verifikasi membuktikan bahwa Kemampuan Berpikir Kreatif menjadi faktor-faktor penentu yang signifikan
A cidade convida para caminhar?: Mobilidade urbana e acessibilidade na área central de Brasília – o setor comercial Sul
Authors: Barros Sulivan Charles
Published: January 2021

From the urban point of view, walkability is the mode of transport where the highest level of contact with the urban environment occurs and provides the most intense exchange between its agents. For this reason, it produces the greatest interaction with city life, promoting an almost organic relationship. Thus, primarily the walk of so repeated and automated is little reflected as an act in itself and can be held responsible for the reduced importance given to it in the treatment of urban space in Brazilian cities. And this occurs both in its understanding as a circulation system, as in its planning and formal spatial repercussion, responsible for generating an outline of urban design. Thus, commuting on foot, along with those who practice it, are systematically relegated by urban technology to a secondary level, where the understanding that adequate treatment of sidewalks and crossings predominates constitutes a kind of urban privilege, a luxury wasted on a second-class user. In this context, the research sought to understand the quality of the walkability and accessibility environment in the central region ofBrasília - the Southern Commercial Sector (SCS), considering the microscale (or street scale), as well as a survey of the physical system for accessibility : public facilities / urban barriers, urban furniture, sidewalks and shelters.
Formação de professores a distância e início de carreira: Significando as aprendizagens da docência
Authors: França-Carvalho Antonia Dalva , Araújo Zilda Tizziana Santos
Published: January 2021

Se formar professores é uma tarefa desafiadora, aprender a ser professor consiste em um luta diária de um processo formativo, continuum, daqueles que iniciam a carreira. Quando esta formação ocorre à distância o desafio pode ser maior, dadas as condições conjunturais e estruturais desta modalidade de ensino, cuja demanda é cada vez maior em nossa sociedade. Aprender a ser professor é uma ação pautada em movimentos contínuos de aquisição, equilibração, modificação e reorganização dos saberes e fazeres profissionais, que constroem a identidade docente. Por isso tornar-se professor é um caminho longo, delicado, por vezes desgastante e solitário, requerendo o comprometimento daqueles que se propõem ao ofício de ensinar. Contudo, é, também, tempo e espaço para descobertas, encantamento, desenvolvimento do sentimento de pertencimento à profissão e ressignificação dos modos de ser, viver e ver a docência. Este livro traz as reflexões acerca das aprendizagens vividas na formação de professores na EaD e no início da carreira docente. Especificamente promove a reflexividade em cada um dos tempos e espaços formativos. E, de modo geral, ratifica a defesa de articulação entre universidade e o chão da escola, principais pilares de aquisição dos saberes professorais e devem ser analisadas em suas práticas formativas, de acolhimento e orientação. Os diálogos aqui promovidos são valiosos para quem deseja conhecer melhor sobre o professor iniciante e suas experiências ao longo do seu processo formativo durante a entrada na carreira docente. Sua leitura certamente aguçará a curiosidade epistemológica da comunidade preocupada com o campo da formação e da prática formativa de modo geral, considerando suas especificidades e singularidades.
The problem of unification of the Romanian principalities in 1859 in Romanian historiography
Authors:   Alexandru Ioan Cuza University, Tsurkan Kristina V.
Published: January 2021

The study aims to describe one of the key and crucial events in the national history of modern Romania from the Romanian historiography's perspective. The author analyses the creation of a unitary state as a result of the unification of the Romanian Principalities of Moldova and Wallachia in 1859 under the leadership of Alexandru Ioan Cuza, who was elected as the ruler in each of those regions. This research provides valuable information on the issue of the Romania-Russia relations in the period of 1858–1862, when according to the Paris Convention of 7/19 August 1858 objective external conditions were created not only for the unification of the Romanian principalities, but also for the administrative reorganization and expansion of independence of the unitary Romanian state. The unification of the Romanian principalities, which in foreign policy terms was accompanied by a clash of interests of major powers (the Austrian, Ottoman, Russian Empires, Great Britain, and France), took place in those specific conditions that were not suitable for Russia's positions in Southeastern Europe and the Balkans. Nevertheless, the historiography does not question the role of Russian foreign policy as a factor that contributed to the international recognition of the young Romanian state, as well as the significance of the diplomatic activities of the Russian consuls in Bucharest and Jassy. That is why the introduction of Russian diplomatic reports that reflect the attitude of Russian consuls to Prince Cuza's policy and their connection with the Romanian elite is still a crucial task for historiography.
On the question of the role of the «Russian factor» in the development of Serbian statehood (1878–1903)
Authors:   Institute of Slavic Studies, Russian Academy of Sciences, Danchenko Svetlana I.
Published: January 2021

The study based on an analysis of the documents from Russian archives examines the issues of Russia's policy towards Serbia and the role of the so-called Russian factor in the formation of Serbian statehood after the Congress of Berlin of 1878. During this period, Serbia began to move into the era of the Austrian-Hungary economic and political influence. With the growth of the pro-Austrian orientation of the Serbian ruling elite, Russia's influence was declining. However, in St. Petersburg a course on the «Serbian issue» was developed, which was consistently pursued in the last quarter of the 19th century, relying on the traditional Russophile sentiments of the Serbian people, with the support of the opposition forces to the Obrenović regime. The activities of Russian diplomats in Serbia were aimed at stabilizing political life in the country, progressive development of independent Serbia and strengthening of its sovereignty.
Serbia's struggle for economic independence in the late 19th–early 20th centuries
Authors:   Institute of Slavic Studies, Russian Academy of Sciences, Kireeva Ekaterina S.
Published: January 2021

The study is devoted to the question of economic independence of Serbia at the end of the 19th–the beginning of the 20th century. At the time Serbian economy and trade were deeply dependent on Austria-Hungary who was Serbia’s main trade partner. Not able to export its goods through any other avenues Serbia strongly relied on Austria-Hungary not only as the main consumer of Serbian agricultural goods but also as a trade mediator between Serbia and the rest of Europe. At the same time such trade relations were discriminative towards Serbia as Austria-Hungary often used Serbia’s dependent position to reach her own economic and political goals. The beginning of the 20th century was marked by Serbia’s attempts to break away from these disadvantageous ties and to find new trade partners and markets for her products.
Montenegrin ruling dynasty of Petrović-Njegoš and the formation of national statehood
Authors:   Institute of Slavic Studies, Russian Academy of Sciences, Strunina-Borodina Natalia G.
Published: January 2021

The study traces the history of the Montenegrin lands during the reign of the Petrović-Njegoš family that lasted for more than two centuries, and also examines the main milestones in the formation of Montenegro’s national statehood. Despite the constant external threat (mainly from the Ottoman Empire), self-identity of the Montenegrin people was not eliminated. Throughout the 19th century the formation of state institutions was taking place within the country; with constant help from the Russian Empire Montenegro received recognition of its independence following the results of the Russo-Turkish war of 1877–1878 and the status of a kingdom in 1910.
Towards Spheres of Influence and the End of the «Balkan Polyphony»: Southeast Europe in the Strategic Calculations of Great Britain at the Final Stage of World War II
Authors:   Lomonosov Moscow State University, Aganson Olga I.
Published: January 2021

The research analyzes Britain’s approaches to the post-war arrangement of the political space of Southeastern Europe at the final stage of World War II. In an effort to maintain its status as a global power, Great Britain took an active part in developing the foundations of a new world order. British strategic planning paid special attention to the Balkan region, where British interests traditionally clashed with the Russian/Soviet ones. The author tries to trace the elements of continuity and variability in British policy in the Balkans. This will enable us to get a more nuanced understanding of the new balance of forces in the region, one of the main manifestations of which was the extinction of the «Balkan polyphony».
The economic development of Bulgaria in the 1960s according to the Soviet diplomats (based on the documents from the Foreign Policy Archive of the Russian Federation)
Authors:   Institute of Slavic Studies, Russian Academy of Sciences, Volokitina Tatyana V.
Published: January 2021

The paper examines the formation and implementation of Bulgaria's economic policy in the 1960s, which are believed to be the time of the formation of the regime of personal power of Todor Zhivkov. The materials of the Archive of Foreign Policy of the Russian Federation analysed by the author testify to the intensive work of the office of the economic adviser of the Embassy of the USSR as well as its complexity. It is stated that in fact Moscow received objective and diverse data on the economic policy of the Bulgarian state, reflecting its unique position – the intention of the national leadership to bring the country on the path of scientific and technological progress through economic acceleration and comprehensive rapprochement with the Soviet Union, that is consistent with the views of the Bulgarian government on national and state interests of the country.
Yugoslav Socialism: A View from Hungary (1956)
Authors:   Institute of Slavic Studies, Russian Academy of Sciences, Kimura Kaori , Stykalin Alexander S. ,   Institute of Slavic Studies, Russian Academy of Sciences
Published: January 2021

The authors focus is on the Hungarian attitude to the Yugoslav experience of building socialism in the conditions of the socio-political upsurge that preceded the uprising of 1956. The authors consider the views on Tito's Yugoslavia and its policies of both the leaders of the ruling Hungarian Workers' Party and the internal party reformist-minded opposition.
Filosofi Research Dalam Upaya Pengembangan Ilmu
Authors: Agustang Andi
Published: January 2021

Dengan mengucapkan syukur kehadirat Allah SWT, atas Rahmat dan Karunia- Nya, sehingga tulisan ini dapat diselesaikan dan diterbitkan. Materi yang dituangkan dalam buku ini diilhami oleh Guru Penulis (Bapak Prof Dr. Rusidi.M.S.) melalui bahan-bahan/materi-materi kuliahNya selama satu semester. Ketika itu penulis masih belajar pada program Magister (S2) di Universitas Padjadjaran Bandung. Materi yang dikemukakan dalam buku ini hanyalah merupakan garis-garis besar yang masih perlu dikembangkan lebih lanjut. Untuk itu kepada para pemakai diharapkan dapat lebih memperkaya pengetahuan- nya dengan mempergunakan sumber-sumber lain yang erat kaitannya dengan masalah yang dibahas dalam buku ini. Harapan penulis semoga buku yang sederhana ini dapat menambah bahan bacaan, utamanya bagi para pengembara/pencinta dan pengembang ilmu pengetahuan. Semoga buku ini memberi manfaat bagi pembacanya, terutama dalam melaksanakantugas-tugas penelitian dalam rangka pengembangan ilmu. Kepada yang tersayang saudara editor dan semua pihak yang membantu terbitnya buku ini, kami haturkan terima kasih yang sebanyak- banyaknya. Tiada gading yang tak retak, demikian bunyi pepatah. Begitupula buku ini, tentu tidak luput dari berbagai kekurangan. Oleh karena itudiharapkan kritik konstruktif untuk kesempurnaannya.
Menangkal Kepunahan Bahasa Tegalan
Authors: Fathurozi
Published: January 2021

Kondisi ini, menjadikan bahasa lokal sulit berkembang dan malah makin terpinggirkan, dan kehilangan maknanya. Padahal bahasa Tegalan memiliki nilai-nilai sosial bisa dijadikan modal kerukunan.Ungkapan bahasa Tegalyang mengandung nilai sosial, penuh kearifansekaligus sebagai seperangkat pengetahuan kehidupan sosial.Wilayah yang terkenal dengan sebutan “Jepangnya Indonesia” terdapat ungkapan-ungkapan yang mengandung nilai sosial yakni.Pertama “Laka Musuh Bala Kabeh” yang artinya “Kita tidak punya musuh, semua sahabat.
UAS TEORI KOMUNIKASI
Authors: elanda adam rihbi
Published: January 2021

adam rihbi elanda fisip 180900025
TAOK1 is a differentially expressed gene in human metastatic breast cancer, in the brain and in the lymph nodes.
Authors: Mamoor Shahan
Published: January 2021

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that the TAO kinase 1, encoded by TAOK1, was among the genes whose expression was most different in the brain and lymph node metastases of patients with metastatic breast cancer. TAOK1 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Importantly, expression of TAOK1 in primary tumors was significantly correlated with patient distant metastasis-free survival in patients with breast cancer. Modulation of TAOK1 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain while evading immune clearance in the lymph nodes in humans with metastatic breast cancer. These data are one piece of evidence suggesting a common ancestor or tumor clone for brain and lymph node metastases that originate from the primary tumor, alluding to patterns in developmental origin and migratory pathways through the lymph node in human brain metastatic breast cancer.
Is urban growing of fruit and vegetables associated with better diet quality and what mediates this relationship? Evidence from a cross-sectional survey.
Authors: Mead Bethan , Hardman Charlotte , Christiansen Paul , Davies Jessica , Falagán Natalia , Kourmpetli Sofia , Liu Lingxuan , Walsh Lael
Published: January 2021

Urban agriculture (UA), the growing of fruits and vegetables in urban and peri-urban areas, may improve food security and access, public health and dietary quality on both a broad and personal scale. However, there is little research on the relationship between UA and diet, and potential mediating factors are also unclear. This study aimed to investigate if proximity to and engagement with UA is associated with better diet quality, and what accounts for this relationship. UK-based adults (N=583, 69% Female) completed measures of proximity to and engagement with UA, perceived access to fruits and vegetables, health and ethical food choice motivations, connection with nature, psychological distress and dietary quality in an online survey. Participants were recruited from UA-related groups and the general public. Proposed relationships were analysed using a structural equation model. Greater proximity to and engagement with UA was associated with greater perceived access to fruits and vegetables, more health-related food choice motivations, more ethical-related food choice, feeling more connected with nature, and, surprisingly greater psychological distress. Furthermore, proximity to and engagement with UA was indirectly associated with better diet quality via health-, and ethical-related, food choice motivations. While the direct pathway between proximity to and engagement with UA and diet quality was not significant, UA is associated with better diet quality, partly via healthier and ethical food choice motivations. Upscaling UA may have benefits for dietary quality via these factors, and more research is needed to test causal relationships and understand these complex interactions.
Limits on Simulation Approaches in Intuitive Physics
Authors: Ludwin-Peery Ethan , Bramley Neil R , Davis Ernest , Gureckis Todd Matthew
Published: January 2021

A popular explanation of the human ability for physical reasoning is that it depends on a sophisticated ability to perform mental simulations. According to this perspective, physical reasoning problems are approached by repeatedly simulating relevant aspects of a scenario, with noise, and making judgments based on aggregation over these simulations. In this paper, we describe three core tenets of simulation approaches, theoretical commitments that must be present in order for a simulation approach to be viable. The identification of these tenets threatens the plausibility of simulation as a theory of physical reasoning, because they appear to be incompatible with what we know about cognition more generally. To investigate this apparent contradiction, we describe three experiments involving simple physical judgments and predictions, and argue their results challenge these core predictions of theories of mental simulation.
Sex, drugs, and genes: Illuminating the moral condemnation of recreational drugs
Authors: Karinen Annika , Wesseldijk Laura , Jern Patrick , Tybur Joshua M.
Published: January 2021

Over the past decade, evolutionary psychologists have proposed that many moral stances function to promote self-interests, and behavioral geneticists have demonstrated that many moral stances have genetic bases. We integrate these perspectives by examining how moral condemnation of recreational drug use relates to sexual strategy (i.e., being more versus less open to sex outside of a committed relationship) in a sample of Finnish twins and siblings (N = 8,118). Twin modeling suggested that genetic factors accounted for 53%, 46%, and 41% of the variance in drug condemnation, sociosexuality, and sexual disgust sensitivity, respectively. Further, approximately 75% of the phenotypic covariance between drug condemnation and sexual strategy was accounted for by genes, and there was substantial overlap in the genetic effects underlying both drug condemnation and sexual strategy (rg = .41). Results suggest that some moral sentiments are calibrated to promote strategic sexual interests, which arise partially via genetic factors.
Content Creation, Dissemination and Preservation: Disrupting the Status Quo through Technological Interventions
Authors: Panda Subhajit , Chakravarty Rupak
Published: January 2021

Disasters, either natural and man-made, adversely affect humanity including human lives and tangible assets. Knowledge as the indisputable gold standard for growth and progress of civilization also destroyed during such disasters. This should not impediment the creation of knowledge. Instead, efforts should be made to find measures which can ensure the longevity of resources for posterity. In this paper, the authors have discussed tools after evaluation and comparison which can use by learners and educators for creation, dissemination and preservation of e-content, especially multimedia. The tools acknowledged for this motive are either cost-free or the basic version is free, or it offers educators & learners some extended free versions. This paper also highlights the resistance of Indian educators to this changing essence of learning from conventional to online.
Geological and geotechnical investigations of Tapovan-Vishnugad Hydroelectric Project, Chamoli District, Uttarakhand, India
Authors: Naithani Ajay K. , Murthy K. S. Krishna
Published: January 2021

The Tapovan- Vishnugad Hydroelectric Project is located in the Dhauliganga and Alaknanda valleys, where the Central Crystallines are composed mainly of medium- to high-grade metamorphics represented by augen gneisses, metabasics, fine­ grained quartz-mica gneisses, micaschists, quartzites, and coarse-grained garnet-biotite-kyanite gneisses. Towards the south, they are thrust over the Lesser Himalayan rocks of the Garhwal Group along the Main Central Thrust. The study aims at modelling the effects of geological structures for determining the potentially fractured or weak zones in underground excavations. For this purpose, Q and RMR values are obtained for each rock type. The in situ deformation modulus, cohesion, and friction angle are estimated to design support systems in unstable zones.
Dust versus Dust: Aluminum Therapy and Silicosis in the Canadian and Global Mining Industries
Authors: Jorgenson Mica , Sandlos John
Published: January 2021

By the 1930s, silicosis – a debilitating lung disease caused by the inhalation of silica dust – had reached epidemic proportions among miners in the gold-producing Porcupine region of northern Ontario. In response, industrial doctors at the McIntyre Mine began to test aluminum powder as a possible prophylactic against the effects of silica dust. In 1944, the newly created McIntyre Research Foundation began distributing aluminum powder throughout Canada and exported this new therapy to mines across the globe. The practice continued until the 1980s despite a failure to replicate preventative effects of silicosis and emerging evidence of adverse neurological impacts among long-time recipients of aluminum therapy. Situated at the intersection of labour, health, science, and environmental histories, this article argues that aluminum therapy represents an extreme and important example where industry and health researchers collaborated on quick-fix “miracle cures” rather than the systemic (and more expensive) changes to the underground environment necessary to reduce the risk of silicosis.
Evaluating the quality of resilience apps for military members and public safety personnel
Authors: O’Toole Kaitlin , Brown Cary A.
Published: January 2021

LAY SUMMARY

A growing number of smartphone apps are being recommended to help build resilience. It is important to test whether these apps are of good quality and evidence-based. This study systematically evaluated 12 popular resilience-related apps for military and public service personnel and found that the majority were of high quality.
РОЛЬ БІЛКІВ ГОСТРОЇ ФАЗИ ПРИ СТРЕСОВОМУ НЕТРИМАННІ СЕЧІ
Authors:   д.мед.н., професор, Івано-Франківський національний медичний університет, м.Івано-Франківськ, Україна, Литвинець Людмила Ярославівна , Литвинець Владислава Євгенівна ,   асистент, Івано-Франківський національний медичний університет, м.Івано-Франківськ, Україна, Горовий Віктор Іванович ,   к.м.н., доцент, Вінницький національниймедичний університетім.М.І.Пирогова, м.Вінниця, Україна, Литвинець-Голутяк Уляна Євгенівна ,   к.м.н, доцент, Івано-Франківський національний медичний університет, м.Івано-Франківськ, Україна
Published: January 2021

Стресове нетримання сечі –одне з найбільш поширених захворювань серед жіночого населення, вкрай негативно позначається на якості життя пацієнток. Серед факторів, які зумовлюють зміни при запальному процесі, велике значення мають так звані білки гострої фази.Беручи до уваги загальну біологічну функцію СРБ, слід вважати закономірним знаходження цього білка безпосередньо в "осередках ураження". Метою нашої роботи стало дослідження вмісту СРБ у сечі та крові пацієнтів зі стресовим нетриманням сечі.Нами 45 хворих на СНС віком від 35 до 75 рр. Групу контролю склали 25 здорових жінок аналогічного віку. У сироватці крові хворих на СНС при поступленні реєстрували підвищення рівня СРБ, практично у всіх хворих він досягав «гострозапального» діапазону і становив в середньому 15,64±3,56 мг/л (р<0,001). Одночасне визначення СРБ у сечі хворих на СНС виявило концентрації біомаркера, що в 4-5 разів перевищували показники в крові і становили в середньому 63,76±4,25 мг/л (р1<0,001).
ПОПЕРЕДЖУВАНІСТЬ ЗАХВОРЮВАНЬ І ВІДВОРОТНІСТЬ ПРИЧИН СМЕРТІ ПЕРЕДЧАСНО НАРОДЖЕНИХ ДІТЕЙ З ВНУТРІШНЬОУТРОБНОЮ ІНФЕКЦІЄЮ
Authors:   канд. мед. наук, доцент кафедри неонатології Харківської медичної академії післядипломної освіти, м.Харків, Україна, Сандуляк Т.В.
Published: January 2021

We carried out research about disease prevention and avoiding of death causes in premature babies with different body masses and intrauterine infections at the modern perinatal center. Under conditions of help localization to pregnant women and newborns and implementation of acknowledged standards of the evidence-based medicine and perinatal strategies of health care to mother and child, we found out some demographic changes in the structure of birth giving, diseases and death of premature babies. Although there is a significant improvement of medical care quality to pregnant women and newborns, as well as an increase in the survival rate among premature newborns with very little and extremely little body masses, a number of newborns has grown who suffered from long-lasting infections and hypoxi before birth, which caused negative disease side-effects
PREREQUISITES FOR THE ACTIVATION OF THE ARCHITECTURAL AND HISTORICAL ENVIRONMENT
Authors: Киселева Алла Александровна
Published: January 2021

The architectural and historical environment concentrates and integrates the main elements of the city cultural values, having a high uniqueness rating. It structures and brings unity and identity to the city, while constantly adapting to changing social demands. The modern stage of the architectural and historical environment development is that the atmosphere of the formed space becomes anachronistic, while its content, perception and experience of use are changing. There is a need for the successive development of historical values and the acquisition of new environmental qualities. The architectural and historical environment faces new challenges and tasks.
Economic efficiency of cultivation of pumiselect clone root in commodity nursery
Authors:   Mykolayiv National Agrarian University, Kovalenko А. , Bushilov V. ,   Uman National University of Horticulture
Published: January 2021

Economic efficiency of cultivation of pumiselect clone root in commodity nursery The article highlights the results of the study of industrial technological models of growing clonal rootstocks for legumes by cuttings. The efficiency of the basic stages of cultivation (vertical cuttings, horizontal cuttings, uterine cuttings, nursery) was established. The problems that arise in the process of production of cuttings according to different technological models are highlighted, and the directions of their solution are offered taking into account the specifics of the region and culture. The advantages of the promising direction of growing the rootstock pumiselect with woody cuttings are proved and substantiated. Keywords: clonal rootstock, method of reproduction, economic efficiency, profitability, profitability.
Automation of relations with customers as a tool of management of agricultural enterprises
Authors:   Petro Mohyla Black Sea National University, Mytskevych N. , Mytskevych D. ,   Petro Mohyla Black Sea National University
Published: January 2021

Automation of relations with customers as a tool of management of agricultural enterprises The article considers the use of CRM-system in the business activity of an agricultural enterprise. The application of automated technology as a tool for transparency of the enterprise, customer relationships and the benefits that gives business this innovation, aimed at building a sustainable business strategy. The influence of the CRM-system on the efficiency of work with clients through the mechanism which includes the improved use of the information, reasonable behavior of sale and customer service and allows to optimize activity of the enterprise is defined. Keywords: automation, innovation, CRM-system, customer relations, management, enterprise.
Proprioceptive Stimulation of the Articulatory Muscles for Restoration of Speech and Swallowing
Authors:   Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University (a Federal Government-funded Educational Institution of Higher Education), Russian Federation Ministry of Health, Mozheiko E.Yu. ,   Krasnoyarsk, Russian Federation, Prokopenko S.V. ,   Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University (a Federal Government-funded Educational Institution of Higher Education), Russian Federation Ministry of Health; Krasnoyarsk, Russian Federation, Yasinskaya Ya.V. ,   I.S. Berzon Krasnoyarsk Interregional Clinical Hospital No. 20 (a Territorial Government-funded Healthcare Institution); Krasnoyarsk, Russian Federation, Eremina Yu.O. ,   Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University (a Federal Government-funded Educational Institution of Higher Education), Russian Federation Ministry of Health; Krasnoyarsk, Russian Federation, Piskareva Yu.Yu. ,   RZD-Meditsina Clinical Hospital of Krasnoyarsk (a Private Healthcare Institution); Krasnoyarsk, Russian Federation, Revtovich Ya.O. ,   Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University (a Federal Government-funded Educational Institution of Higher Education), Russian Federation Ministry of Health; Krasnoyarsk, Russian Federation
Published: January 2021

Objective of the Paper: To assess the possibility of supplementing standard speech therapy protocols for dysarthria patients in the acute period of ischemic stroke, with techniques for stimulating the afferent nerves of the mouth and articulatory organs via a proprietary training mask designed to improve proprioception. Key Points: The paper describes a clinical case of using the training mask. Repeated speech evaluations and changes in scores on scales for assessing the severity of speech problems and dysarthria showed that stimulation of the proprioceptive afferents in the mouth and articulatory organs improved mimetic muscle function and speech articulation, contributed to normalizing muscle tone in the articulatory muscles, and reduced speech hesitation. Conclusion: The clinical case described in the paper demonstrates the positive effects of a training mask designed for proprioceptive stimulation of the articulatory muscles in patients with acute ischemic stroke. These results will be of interest to neurologists, speech therapists, and specialists in neurorehabilitation. Keywords: dysarthria, pseudobulbar disorders, extrapyramidal disorders, training mask, ischemic stroke.
Prevention and Treatment of Back Pain: Experts’ Consensus Recommendations
Authors:   A.I. Yevdokimov Moscow State University of Medicine and Dentistry (a Federal Government-funded Educational Institution of Higher Education), Russian Federation Ministry of Health, Vertkin A.L. ,   Moscow, Russian Federation, Shamuilova M.M. ,   A.I. Yevdokimov Moscow State University of Medicine and Dentistry (a Federal Government-funded Educational Institution of Higher Education), Russian Federation Ministry of Health; Moscow, Russian Federation, Knorring G.Yu. ,   A.I. Yevdokimov Moscow State University of Medicine and Dentistry (a Federal Government-funded Educational Institution of Higher Education), Russian Federation Ministry of Health; Moscow, Russian Federation, Sedyakina Yu.V. ,   A.I. Yevdokimov Moscow State University of Medicine and Dentistry (a Federal Government-funded Educational Institution of Higher Education), Russian Federation Ministry of Health; Moscow, Russian Federation, Nosova A.V. ,   A.I. Yevdokimov Moscow State University of Medicine and Dentistry (a Federal Government-funded Educational Institution of Higher Education), Russian Federation Ministry of Health; Moscow, Russian Federation, Aliev Z.K. ,   A.I. Yevdokimov Moscow State University of Medicine and Dentistry (a Federal Government-funded Educational Institution of Higher Education), Russian Federation Ministry of Health; Moscow, Russian Federation
Published: January 2021

Objective of the Review: To present, for internists and general practitioners, two sets of multidisciplinary consensus recommendations for the management of patients with back pain. Key Points: The paper includes short diagnostic protocols, red flag screening protocols, and criteria for involving specialists from related fields, starting physiotherapy, and using a battery of psychological tools. Also covered are criteria for optimal treatment with medications, including fast-acting analgesics (particularly non-steroidal anti-inflammatory drugs) and prolonged-action structure-modifying drugs. Conclusion: The management of patients with non-specific back pain is dealt with by internists or general practitioners. It requires a clear, structured approach to identifying red flags and bringing in specialists from related fields; lifestyle and diet modifications; exercise and physical therapy; a battery of psychological tools; and, without question, optimal treatment with medications, including fast-acting analgesics and prolonged-action structure-modifying drugs. Keywords: non-steroidal anti-inflammatory drugs, back pain, treatment protocol, neurotropic B vitamins, prolonged-action structuremodifying drugs.
A Method for Predicting Repeat Socially Dangerous Acts in Subjects with Organic Mental Disorders
Authors:   Voronezh Regional Clinical Center for Psychoneurology (a Public Healthcare In-stitution of Voronezh Region), Popov S.N. ,   Orlovka Village, Voronezh Region, Russian Federation, Vinnikova I.N. ,   V.P. Serbsky National Medical Research Center for Psychiatry and Narcology (a Federal Government-funded Institution), Russian Federation Ministry of Health; Moscow, Russian Federation
Published: January 2021

Study Objective: To describe a new method for predicting repeat socially dan-gerous acts (SDA) by persons with organic mental disorders. Study Design: This was a comparative study. Materials and Methods: The people studied were 118 male patients with organic mental disorders who had committed SDA and were subject to involuntary medical measures, administered in outpatient or inpatient settings. These patients were divided into a main group, which was made up of 45 men who had commit-ted repeat SDA, and a comparison group, which consisted of 73 men with no history of recidivist criminal behavior in the follow-up period. The main research methods included clinical psychopathological assessments, prospective clinical follow-up (mean duration of follow-up was 8.65 ± 2.17 years), statistical analysis of clinical data, and criminological analysis. Study Results: Mathematical analysis and identification of the main correlation relationships made it possible to develop a questionnaire and a computer program for predicting the possibility of committing a repeat SDA. There are 24 input parameters. This method predicts repeat SDA in 82.9% of cases. For a sample of at least 80 people, the average predictive reliability of this method exceeds 80%, with a minimum reliability no lower than 70% in the event of random fluctuations. The study also showed that even with only one input parameter the method provides a reliable prognosis in almost 70% of cases, and beginning at 23 input parameters its prognostic reliability exceeds 80% and increases with in-crease of the number of input characteristics. Conclusion: The authors have developed a tool for predicting a repeat SDA, and its characteristics, using the pattern proximity method. This tool can be used for patients with any type of disorder. Further multifactorial evaluation of the causes of both initial and repeat SDA in patients with mental disorders provides information for assessing the possibility of predicting such actions. This study gives us a practical data-assessment tool, which can be widely used at any stage of preventive measures against socially dangerous behavior by patients with mental disorders. Keywords: socially dangerous act, organic mental disorders, prognostic methodology.
Factors influencing ecotourism in Wasur national park Merauke regency
Authors: Ririhena Samel W. , Phuk Tjilen Alexander , Cahyono Edi , Cara Alexander Phoek Inez
Published: January 2021

Government planning to promote tourism in Indonesia, including national parks, needs to be more serious to have a positive impact on the economic welfare of a region and the welfare of the community, the same things for Wasur National Park (TNW) in Merauke, Papua Province, Indonesia. This paper reports on the determinant factors of TNW's role in its management as ecotourism and conservation parks. This study uses qualitative methods, with semi-structured interviews and face-to-face. Interviews were conducted with the Department of Tourism, TNW managers, Non-Governmental Organizations, community leaders, religious leaders and researchers from Musamus University and field observers. This research results as follows: TNW has a tourist attraction in the form of a natural panorama consisting of several different spots, many tourists who are not recorded (do not pay entrance fees). Lodging and culinary facilities are still managed traditionally. Therefore, foreign tourists bring their own equipment and needs. In general, transportation to TNW is relatively expensive. The Local Government provides buses for transportation from Merauke Regency to TNW, but tourists prefer renting a car. Local wisdom has contributed so that the natural conditions of TNW are still well preserved and most are still natural. On the other hand, there has not been a serious effort to promote TNW and partnership cooperation with related industries to optimize the potential of TNW has not been done much. The results of this study are crucial for the Government, industry, and the community in a joint effort to optimize the potential of TNW ecotourism to obtain a positive impact on economic life, improve community welfare and conservation.
The reaction of American Luxury tourists visiting Rwanda during 2018-2019 Ebola outbreaks
Authors: Ngamije James
Published: January 2021

Several cases of Ebola virus diseases (EVD), have been discovered in Africa. The 2018–2019 outbreak of the Ebola virus disease (EVD) in North Kivu and Ituri provinces has been declared International public health emergency. Rwanda as a neighboring country was on high alert, with the possibility of the disease crossing its borders. As a result, some countries, issued travel alerts to their citizens to avoid travel to Congo or nearby countries to include Rwanda. This study investigates the impact of Ebola outbreak on American Luxury tourists in Rwanda, evaluating its findings in light of the 2018–2019 outbreak of Ebola virus disease (EVD) in Democratic Republic of Congo. It concludes that this EVD did not discourage this target group of tourists from undertaking their planned itineraries in Rwanda.
Intraoperative seizure outcome of levetiracetam combined with perampanel therapy in patients with glioma undergoing awake brain surgery
Authors: Motomura Kazuya , Chalise Lushun , Shimizu Hiroyuki , Yamaguchi Junya , Nishikawa Tomohide , Ohka Fumiharu , Aoki Kosuke , Tanahashi Kuniaki , Hirano Masaki , Wakabayashi Toshihiko , Natsume Atsushi
Published: January 2021

OBJECTIVE

This study aimed to evaluate the efficacy of levetiracetam (LEV) combined with perampanel (PER) therapy for intraoperative seizure treatment to determine whether a combination of LEV and PER can aid in the prevention of intraoperative intractable seizures during awake surgery.

METHODS

The authors performed a retrospective cohort study in 78 consecutive patients with glioma who underwent awake surgery using intraoperative direct electrical stimulation mapping. To prevent intraoperative seizures, 50 patients were treated with the antiepileptic drug LEV only (LEV group) from January 2017 to January 2019, while the remaining 28 patients were treated with LEV plus PER (LEV + PER group) between March 2019 and January 2020. LEV (1000–3000 mg) and/or PER (2–4 mg) were administered before the surgery.

RESULTS

Preoperative seizures with International League Against Epilepsy (ILAE) class II–VI occurred in 44% of the patients in the LEV group and in 35.7% of patients in the LEV + PER group, with no significant difference between groups (p = 0.319). Total intraoperative seizures occurred in 18 patients (36.0%) in the LEV therapy group and in 2 patients (7.1%) in the LEV + PER group (p = 0.009). Of these, there were no patients (0%) with intractable seizures in the LEV + PER group. Regarding factors that influence intraoperative seizures in glioma patients during awake brain surgery, multivariate logistic regression models revealed that the occurrence of intraoperative seizures was significantly related to the involvement of motor-related regions (positive vs negative, HR 6.98, 95% CI 1.71–28.56, p = 0.007), preoperative seizure (ILAE class II–VI vs ILAE class I, HR 4.44, 95% CI 1.22–16.11, p = 0.024), and LEV + PER group (positive vs negative, HR 0.07, 95% CI 0.01–0.44, p = 0.005). Treatment-related adverse effects were rare and mild, including sleepiness, tiredness, and dizziness in both treatment groups.

CONCLUSIONS

This study demonstrates that LEV + PER therapy is significantly associated with a lower risk of intraoperative seizures compared with LEV therapy alone in patients with glioma during awake brain mapping. These findings will help neurosurgeons conduct safe and reliable awake surgeries and reduce the rate of intraoperative intractable seizures during such procedures.