bluuebunny/crossref_metadata_2025 huggingface dataset:
Outcomes of multidisciplinary management of pulmonary nodules in a tertiary center
Authors: Öztürk Aktaş Özge , Demir Ahmet Uğur , Selçuk Ziya Toros
Published: September 2024

Objective: A multidisciplinary approach is recommended for managing pulmonary nodules. This study aimed to examine the malignancy rates, malignancy determinants, and follow-up results of patients with pulmonary nodules whom the multidisciplinary team evaluates.
Methods: Clinical characteristics of the patients, radiological and histological characteristics of the nodules, and the follow-up outcomes were documented retrospectively. A total of 94 patients with solitary pulmonary nodules (SPNs) (n=58) and multiple pulmonary nodules (MPNs) (n=36) were included in the study.
Results: Our study showed that malignancy risk increased with irregular nodule margins (p < 0.008). Patients who had tissue sampling from suspected nodules exhibited markedly higher rates of previous malignancy than those who did not (58.5% vs. 19.5% p<0.001). For the patients with solitary pulmonary nodule (SPN), the group for whom biopsy was planned had more underlying malignancy (p=0.011) and had a bigger nodule size of 10 mm (range, 8.0-13.25 mm) vs 15.00 mm (range, 10.0-19.75 mm) (p=0.003). Among the patients who have multiple pulmonary nodules (MPN), eighty-four percent of patients in the biopsy group had underlying malignancy diagnoses, whereas this rate was 26% in the CT follow-up group (p=0.002). Adenocarcinoma was the most common SPN histology and squamous cell carcinoma for MPNs. The Multidisciplinary Thoracic Oncology Board identified malignancy in 60% of patients with SPNs and 92.3% of those with MPNs/
Conclusions: Patients evaluated in the multidisciplinary tumor board consist of a very diverse patient group. Discerning between malignant and benign conditions relies heavily on examining nodule features and assessing malignancy history.
Pengaruh Suhu Ekstraksi dan Kecepatan Pengadukan terhadap Karakteristik Crude Ekstrak Stevia
Authors: Dewi Luthfi Kurnia , Milenia Rohmah , Islam Livya Safira , Ismuyanto Bambang
Published: September 2024

Stevia is a natural sweetener that is 250-300 times sweeter than sucrose and is low in calories. Stevia sweeteners are obtained from the extraction of stevia leaves. This study aims to determine the effects of temperature and stirring speed on the characteristics of crude stevia extract (yield, brix value, and IR spectrum). Maceration extraction was conducted with 70% ethanol for 1 hour, varying the temperature (28 â„ƒ, 40 â„ƒ, 55 â„ƒ) and stirring speed (0 rpm, 50 rpm, 100 rpm, 150 rpm). The results showed that a temperature of 40 â„ƒ produced the highest yield at each stirring speed. The yield increased with the increase in stirring speed at each extraction temperature. The highest brix value was obtained at 55 â„ƒ and a stirring speed of 150 rpm. The IR spectrum results showed that the functional groups in the crude stevia extract were almost identical to those in commercial stevia.
A historical confusion that has long permeated the sex paradox
Authors: Gollo Gustavo
Published: September 2024

A historical misunderstanding permeates nearly every formulation of the sexual reproduction paradox, an age-old conundrum that continues to challenge the foundations of evolutionary theory. Recognizing this error will clarify the problem and facilitate its resolution.
The Conception of Local Economic Development as an Instrument for Sustainable Economic Growth of Territories: Ukrainian Aspect
Authors:   Central Ukrainian National Technical University, Androshchuk Ilona O. , Riedrieiev Rostyslav A. ,   Central Ukrainian National Technical University
Published: September 2024

The aim of this article is to study the conception of local economic development as an instrument for sustainable economic growth of territories in the context of decentralization, including the process of implementation of foreign experience of this conception in Ukrainian realities. The article analyzes modern theories of local economic development. An analysis of the definition of the concept of «local economic development», key elements and basic principles is carried out. The main barriers that hinder local economic development are noted, namely: financial and economic, innovative, social, environmental, political, lack of motivation and controlling system, as well as institutional barrier. The key risks characteristic of the general goals of local economic development are studied, including: risks of physical capital; risks associated with technological innovations; human capital risks; social capital risks, as well as risks related to the macroeconomic environment; risks related to the technological environment; ecological risks; risks associated with the cultural environment; infrastructure-related risks and political and legal risks. The key stakeholders of local economic development have been identified, which include: the government, local self-governments, non-profit organizations, business organizations, international organizations and the population. An analysis of the activities of stakeholders in the measurement of international trends is carried out. The advantages for the development of territories through the use of the conception of local economic development are substantiated. It is proved that the implementation of the conception of local economic development, taking into account the positive experience of foreign countries, will accelerate the development of the domestic economy and reduce the negative dynamics of destructive changes due to military aggression on the territory of Ukraine.
Research of the Trends of Socioeconomic Development of the Regions of Ukraine
Authors:   National University «Chernihiv Polytechnic», Gonta Olena I. , Troian Vladyslava I. ,   O. M. Beketov National University of Urban Economy in Kharkiv
Published: September 2024

The article discusses the current trends in the socioeconomic development of the regions of Ukraine, which remains a critical problem, especially in the context of constant regional imbalances that impede the overall economic stability of the country. The decentralization process, which gave more autonomy to local governments, was expected to mitigate some of these imbalances. However, challenges such as the long-term war, the COVID-19 pandemic, and systemic infrastructure shortages have exacerbated the development gap between regions. Many regions continue to face obstacles related to investment attractiveness, innovation, and efficient use of resources, hindering their economic growth. Therefore, addressing these inequalities is essential to achieve sustainable national development and ensure social cohesion. The aim of this article is to analyze the main trends in the socioeconomic development of the regions of Ukraine and provide recommendations for addressing the existing challenges. The study aims to examine the factors that account for regional differences, assess the impact of decentralization reforms, and identify effective measures to promote balanced regional growth. The study also identifies critical infrastructure gaps that prevent regions from fully exploiting their economic potential. It is concluded that the achievement of balanced socioeconomic development of the regions of Ukraine requires purposeful State intervention and strengthening of interregional cooperation. The data obtained indicate the need to expand investment programs aimed at underdeveloped regions, improve infrastructure and support innovative industries. In addition, continuous optimization of the decentralization process is important, in particular in terms of increasing the transparency and efficiency of local governance. By focusing on these areas, Ukraine can reduce regional disparities, increase economic resilience, and promote sustainable, inclusive growth across the country. The article provides a comprehensive framework for understanding the current state of regional development in Ukraine and offers practical solutions for bridging the socioeconomic gap between regions.
The Impact of Digital Transformations on the Development of the Modern Economic Space: Human Capital, Inclusion, Security
Authors:   West Ukrainian National University, Ptashchenko Olena V. , Kyrylenko Olga P. ,   West Ukrainian National University, Kurtsev Oleksiy Yu. ,   Simon Kuznets Kharkiv National University of Economics
Published: September 2024

Digital transformations, encompassing the integration of the latest technologies into all aspects of life, are fundamentally changing the modern economic space. This process has a profound impact on three key aspects: human capital, inclusion, and security. These factors interact in the context of digital change, as their proper management is crucial for sustainable and equitable economic development. That is why the purpose of the presented work is to determine the impact of digital transformations on the development of the modern economic space in the aspects of inclusiveness, security and human capital development. The main methods presented in the study are: method of analysis, method of synthesis, method of generalization, logical method, method of expert evaluation, method of deduction, method of induction, tabular method, graphical method. The main results of the study include the conclusion that digital technologies pose new requirements on skills and knowledge. Modern business models require highly skilled professionals capable of working with big data, artificial intelligence, cybersecurity, and other advanced technologies. This requires significant changes in education and training, as well as ongoing training and retraining of employees. Digital transformation can also exacerbate social and economic inequalities if an equal access to new technologies is not ensured. Different segments of the population may have unequal access to digital resources and opportunities, which can lead to the exclusion of certain groups from economic activity. Digital transformations are accompanied by an increase in cyber threats such as hacker attacks, identity theft, and fraud. This can jeopardize the security of personal data, business processes and national security. Thus, digital transformations have a powerful impact on the development of the modern economic space, changing the dynamics of human capital, inclusion issues, and security aspects. In order to maximize the positive outcomes of digital change and minimize possible negative impacts, comprehensive measures must be taken, covering educational initiatives, support for inclusion, and strengthening cybersecurity. Only through coherent and strategic approaches can equitable and sustainable development be ensured in the face of rapid technological change.
Meminimalisir Patologi Kehamilan dengan Deteksi Dini Faktor Resiko
Authors: Irawati Fanni Siska , Yanti Linda , Dewi Feti Kumala
Published: September 2024

ABSTRAK Data Angka Kematian Ibu (AKI) di Indonesia mengalami peningkatan setiap tahunnya, dimana AKI meningkat dari 4.627 kematian tahun 2020. Angka AKI wilayah Banjarnegara pada tahun 2022 mencapai 130,83 per 100.000 kelahiran hidup. Upaya menurunkan angka kematian ibu adalah peningkatan pengetahuan melalui penyuluhan. Tujuan pada pengabdian ini yaitu meminimalisir patologi kehamilan dengan deteksi dini faktor risiko. Metode yang digunakan adalah metode penyuluhan. Alur kegiatanya meliputi persiapan dan koordinasi, skrining peserta, pretest, penyuluhan, pemeriksaan deteksi dengan Skor Poedji Rochjati, postest, monitoring dan evaluasi. Kegiatan dilakukan di rumah kader Bantarwaru 24 desember 2023 dengan jumlah 9 peserta. Hasil dari penyuluhan sebagian besar usia reproduksi sehat 7 orang (77,8%), sebagian besar pendidikan dasar 6 orang (66,6%), gravida terbanyak multigravida 6 orang (66,6%) dan paritas terbanyak  pada primipara 8 orang (88,8%).Berdasarkan skor poedji rochjati terdapat 2 (22,2%) dengan hasil scrinning usia >35 tahun memiliki kategori kehamilan risiko tinggi (KRT).Berdasarkan hasil Pengabdian Kepada Masyarakat dari hasil pretest mayoritas memiliki nilai baik sejumlah 4 responden (44,4%). Berdasarkan hasil Pengabdian Kepada Masyarakat dari hasil prostest terdapat peningkatan pengetahuan baik sebanyak 6 orang (66,6%) karena memperhatikan dengan baik saat diberi materi penyuluhan. Kata Kunci: Kehamilan,Pengetahuan, Faktor Resiko Kehamilan, Deteksi Dini  ABSTRACT Data on maternal mortality rate increases every year, the MMR increased from 4,627 deaths 2020. The Maternal Mortality Rate in Banjarnegara Regency in 2022 will reach 130.83 per 100,000 live births. Efforts made to reduce maternal and newborn mortality rates are increasing knowledge through outreach. The aim of this service is to minimize pregnancy pathology by early detection of risk factors. The method used is the extension method. The flow of activities includes preparation and coordination, participant screening, pretest, counseling, detection examination with the Poedji Rochjati Score, posttest, monitoring and evaluation. The activity was carried out at the Bantarwaru cadre's house on December 24 2023 with a total of 9 participants. The results of the counseling were mostly healthy reproductive age 7 people (77.8%), mostly basic education 6 people (66.6%), gravida mostly multigravida 6 people (66.6%) and most parity in primipara 8 people (88 .8%). Based on the Poedji Rochjati score, there were 2 (22.2%) with screening results aged >35 years who had the high risk pregnancy (KRT) category. Based on Community Service results from the pre test results, the majority of respondents had good knowledge, 4 people (44.4 %). Based on the Community Service results from the prostest results, there was an increase in good knowledge by 6 people (66.6%) because they paid good attention when given counseling material. Keywords : Pregnancy, Knowledge, Pregnancy Risk Factors, Early Detection
Edukasi Bantuan Hidup Dasar Tingkatkan Pengetahuan Remaja Menghadapi Situasi Darurat Henti Jantung
Authors: Alex Alex , Handoko Willy , Novitarini Poppy
Published: September 2024

ABSTRAK Serangan jantung di luar rumah sakit merupakan penyebab utama kematian, dengan frekuensi 67 hingga 170 per 100.000 orang. Tingkat kelangsungan hidup sangat rendah jika saksi mata yang melihat kejadian secara langsung terlambat memberikan pertolongan. Tujuan dari kegiatan ini adalah memberikan edukasi bantuan hidup dasar (BHD) kepada remaja untuk meningkatkan pengetahuan remaja menghadapi situasi darurat henti jantung. Kegiatan pengabdian kepada masyarakat (PKM) ini menggunakan metode penyuluhan, demonstrasi, serta praktek RJP pada manekin. Kegiatan didahului pre-test, kemudian dilanjutkan dengan edukasi mengenai materi BHD, demonstrasi resusitasi jantung paru (RJP) pada manekin, praktek langsung RJP pada manekin oleh setiap peserta, diskusi, kemudian diakhiri dengan post-test. Evaluasi dilakukan dengan membandingkan antara nilai pre-test dan post-test. Semua peserta mengalami peningkatan nilai post-test dibandingkan dengan nilai pre-test. Nilai rata-rata pre-test adalah 35,19, sedangkan nilai rata-rata post-test adalah 82,96. Uji Wicoxon mendapatkan p-value 0,000 yang menandakan ada perbedaan signifikan antara nilai pre-test dan post-test. Kegiatan edukasi BHD pada remaja di Kelurahan Siantan Hilir, Kecamatan Pontianak Utara berhasil meningkatkan pengetahuan remaja dalam menghadapi situasi darurat henti jantung. Kata Kunci: Bantuan Hidup Dasar, Remaja, Situasi Darurat, Henti Jantung  ABSTRACT Out-of-hospital cardiac arrest is the leading cause of death, with a frequency of 67 to 170 per 100,000 people. The survival rate is very low if bystanders who see the incident directly are late in providing Basic Life Support (BLS). This activity aims to provide BLS education to teenagers to increase their knowledge of dealing with emergency situations of cardiac arrest. This PKM activity uses counseling methods, demonstrations, and cardiopulmonary resuscitation (CPR) practice on mannequins. The activity was preceded by a pre-test, then continued with education regarding BHD material, demonstration of CPR on a mannequin, direct practice of CPR on a mannequin by each participant, discussion, and then ended with a post-test. Evaluation is carried out by comparing the results of the pre-test and post-test. All participants experienced an increase in post-test scores compared to pre-test scores. The average pre-test score was 35.19, while the average post-test score was 82.96. The Wilcoxon test obtained a p-value of 0.000, indicating a significant difference between the pre-test and post-test scores. BLS educational activities for teenagers in Siantan Hilir Village, North Pontianak District, increased teenagers' knowledge in dealing with emergency situations of cardiac arrest. Keywords: Basic Life Support, Teenager, Emergency, Cardiac Arrest
Edukasi Pencegahan Anemia pada Masa Kehamilan sebagai Upaya Meningkatkan Pengetahuan Ibu Hamil
Authors: R Maria Magdalena Saragi , Doloksaribu Tiurlan Mariasima , Yusniar Yusniar
Published: September 2024

ABSTRAK Anemia memberikan dampak negatif terutama bagi bayi dalam kandungan, seperti mengakibatkan keguguran, bayi lahir tidak cukup bulan, bayi tidak berkembang sempurna. Anemia dianggap sebagai masalah kesehatan masyarakat yang utama pada lebih dari 80% negara di dunia, prevalensi anemia pada kehamilan >20%. Pengabdian kepada masyarakat dilakukan dalam bentuk  edukasi pada ibu hamil berjumlah 30 orang. Tujuan Pengabdian Kepada Masyarakat ini adalah untuk mewujudkan pengabdian kepada masyarakat sebagai salah satu kegiatan Tri Darma Perguruan Tinggi, meningkatkan pengetahuan Ibu hamil tentang anemia sebagai upaya pencegahan anemia.  Dari hasil evaluasi diperoleh pengetahuan ibu hamil sebelum diberikan edukasi mayoritas cukup sebanyak 63,3% dan setelah dilakukan edukasi mayoritas baik  sebanyak 95.7%. Dengan adanya kegiatan Pengabdian Kepada Masyarakat ini diharapakan kepada Ibu hamil dapat meningkatkan pengetahuan mengenai anemia sebagai upaya pencegahan anemia pada ibu hamil. Kata Kunci: Edukasi, Pengetahuan, Ibu Hamil  ABSTRACT Anemia has a negative impact, especially on babies in the womb, such as resulting in miscarriage, babies born not at term, babies not developing fully. Anemia is considered a major public health problem in more than 80% of countries in the world, the prevalence of anemia in pregnancy is >20%. Community service was carried out in the form of education for 30 pregnant women. The aim of this Community Service is to realize community service as one of the Tri Darma activities of higher education, increasing pregnant women's knowledge about anemia as an effort to prevent anemia.  From the evaluation results, it was found that the majority of pregnant women's knowledge before being given education was adequate at 63.3% and after education the majority was good at 95.7%. With this Community Service activity, it is hoped that pregnant women can increase their knowledge about anemia as an effort to prevent anemia in pregnant women. Keywords: Education, Knowledge, Pregnant
Application of Guarantee contracts in Islamic Financial Transaction: Analysis of BNM and AAIOFI
Authors: Busari Saheed , Suleiman Hassan , Salhab Belal
Published: September 2024

A guarantee (Kafalah) is considered an effective Islamic finance contract aimed at providing assurance and security by having a third party; the guarantor, commit to fulfilling the financial obligations of the debtor in case of default. However, Bank Negara Malaysia (BNM) policy document considered guarantee as the term (kafālah) while the Accounting and Auditing Organization for Islamic Financial Institutions (AAIOFI) considered it as the term Damān. The term guarantee falls within the category of non-compensatory contract in classical Islamic financial contracts whereby there are no returns or compensation available for contracts like benevolence loans (Qard), gifts (Tabarru/Hibah), guarantee (Kafalah), and assignment of debt (Hawalah). In the modern financial setting, this might not fulfill one of the objectives of Islamic financial institutions to offer services for profit. This study explores the application of Guarantee (Kafalah) as a non-compensatory and noncommutative contract, falling under the category of Uqud Ghair Mua’wadha in Islamic Financial Institutions. Contracts such as benevolence loans (Qard), gifts (Tabarru/Hibah), guarantees (Kafalah), and assignment of debt (Hawalah) are characterized by the absence of return or compensation.
This study uses the doctrinal approach of the qualitative method in exploring juristic meaning, justification, and implications of the shariah terms. It analyses the sustainable implication of its application in contemporary Islamic finance institutions between BNM and AAIOFI. This study found that despite the classical implication of guarantee as a non-compensatory contract guarantee contracts cannot yield a direct profit; yet can generate income through, Wakālah (agency fee), such as issuing LCs guarantees. These may be charged based on expenses incurred, potentially in amount-based (possibly slabs) but not time-based structures. The finding shows that the comparative analysis of regulatory frameworks by BNM and AAIOFI underscores the challenges of harmonizing global standards with local contexts, highlighting the necessity for ongoing dialogue and collaboration to ensure coherence and adaptability in Islamic finance regulation.
Peraturan Majlis Kebangsaan Bagi Hal Ehwal Ugama Islam Malaysia 2022: Ulasan Terhadap Pindaan Jawatankuasa Muzakarah Majlis Kebangsaan Bagi Hal Ehwal Agama Islam
Authors: Mahmud Ahmad Tarmizi , Mohd Subri Irwan , Abdul Majid Nasir
Published: September 2024

Abstrak
Majlis Kebangsaan Bagi Hal Ehwal Agama Islam (MKI) merupakan satu entiti yang ditubuhkan oleh Majlis Raja-Raja pada 17 Okotober 1968. Ia merupakan badan yang bertanggungjawab dalam melakukan penyelarasan pentadbiran agama Islam di seluruh negara berdasarkan kepada bidangkuasanya yang termaktub dalam Peraturan Majlis Kebangsaan Bagi Hal Ehwal Ugama Islam Malaysia 1968 (Peraturan MKI 1968). Namun begitu, pada tahun 2022, peraturan ini telah dipinda bertujuan bagi menambahbaik tadbir urus MKI. Pindaan ini telah memberikan nafas baharu kepada kefungsian majlis ini serta beberapa jawatankuasa yang ditubuhkan di bawahnya. Oleh itu, kajian ini dikemukakan bagi meninjau pindaan yang telah dilakukan terhadap jawatankuasa fatwa yang merupakan salah satu jawatankuasa di bawah MKI. Kajian ini berbentuk kualitatif menggunakan metodologi analisis dokumen yang merangkumi buku, akta, enakmen, artikel penyelidikan dan juga Peraturan MKI. Kaedah temubual separa berstruktur dan penelitian secara komparatif juga telah dilakukan dalam mengulas perubahan yang berlaku terhadap jawatankuasa fatwa tersebut. Hasil kajian mendapati terdapat beberapa pindaan telah dilakukan yang merangkumi penubuhan dan perlantikan, keanggotan, tugasan dan juga penjenamaan baharu jawatankuasa tersebut. Didapati pindaan yang telah dilakukan bertujuan memberikan nilai tambah kepadanya tanpa menjejaskan kefungsian asal jawatankuasa ini.
Hadith Preservation: Techniques And Contemporary Efforts
Authors: Babatunde Jaiyeoba Haruna , Osmani Noor Mohammad
Published: September 2024

Hadith is an important source of Islamic teachings. The method of Hadith preservation during the time of Prophet Muhammad (peace be upon him) and after his demise has constantly been criticised by Orientalists and critics of Islam. Most of their objections emphasise that Hadith could not have been accurately transmitted orally over a century. Thus, conducting research on how Hadith has been preserved is crucial, particularly to remind the critics that Allah’s (Subhanahu Wa Ta’ala) promise to protect His Book is not limited to the Qur’an, but also extends to the Hadith, which explains the meanings of the Qur’an. Additionally, it is crucial to continuously discuss the painstaking efforts that went into Hadith preservation, which make Muslims believe with absolute certainty that Hadith were accurately preserved. On this basis, this article discusses the multifaceted landscape of Hadith preservation by exploring the techniques employed and contemporary efforts in preserving this rich Islamic heritage. Relevant books, academic journal articles, lecture notes, and webpages were reviewed in writing this article. The three main techniques that played a significant role in preserving Hadith are memorisation, the principle of practice, and documentation. Moreover, the contemporary efforts that contributed to Hadith preservation include the massive publication of academic books and journals on Hadith, the establishment of faculties in major universities that offer Hadith studies as a specialised academic program, the increase in comparative jurisprudence studies that refer to Hadith as one of the most important references, the need to respond to Orientalist theories on Hadith, and the advent of digital technology.
Rasuah Pilihan Raya: Analisis Hukum Dan Fatwa Di Malaysia Dan Indonesia
Authors: Abdulah Nur Aina , Zakaria Alfons , Kamruzaman Nur Al-Farhain , Hazram Nurul Ain , Gunardi Setiyawan , Nek Mustafa Nik Nur Afiqah
Published: September 2024

Rasuah merupakan perbuatan yang dilarang dan bersalahan dengan agama, akhlak dan undang-undang. Ia boleh berlaku dalam pelbagai cara dan peringkat, termasuklah dalam pilihan raya. Impak rasuah ini amatlah besar, bukan sahaja meruntuhkan akan sebuah masyarakat, malah negara keseluruhannya. Permasalahannya adalah isu-isu rasuah yang berlegar sekitar pilihan raya masih samar-samar belum dibincangkan secara terperinci dari persepektif Syariah. Oleh itu, objektif artikel ini adalah untuk menjelaskan hukum dan fatwa di Malaysia dan Indonesia berkaitan rasuah termasuk isu-isu yang berlegar ketika pilihan raya. Metodologi kajian kualitatif digunakan dengan kaedah pengumpulan data secara analisis kandungan dan tembual pakar. Data kemudiannya dianalisis secara tematik dan deskriptif. Hasil kajian mendapati bahawa hukum asal sesuatu pemberian adalah harus dalam Syariah. Walau bagaimanapun, dalam isu pilihan raya, sekiranya pemberian itu mempunyai niat dan tujuan di sebaliknya, seperti untuk memancing undi dan mengubah kecenderungan politik, maka, hukumnya adalah haram dan perlu ditinggalkan kerana ia tergolong dalam perbuatan rasuah.
PageRank and Regression as a Two-Step Approach to Analysing a Network of Nasdaq Firms During a Recession: Insights from Minimum Spanning Tree Topology
Authors: Tomeczek Artur F. , Napiórkowski Tomasz M.
Published: September 2024

Występowanie wpływowych firm oddziałujących na cały rynek akcji zostało potwierdzone w wielu badaniach bazujących na topologii minimalnych drzew rozpinających. Historycznie, centralne firmy były identyfikowane przede wszystkich na podstawie centralności stopniowej wierzchołków. Niniejszy artykuł przedstawia alternatywną metodę selekcji, stanowiącą połączenie wyników PageRank i klas modularności, która pozwala wyeliminować remisy w rankingach podczas selekcji określonej liczby wierzchołków. Wykorzystano analizę sieciową na podstawie centralności PageRank połączoną z analizą regresji, aby zidentyfikować wpływowe firmy w indeksie Nasdaq-100 podczas trzech ostatnich recesji w Stanach Zjednoczonych. Wykazano zasadność oraz odporność zaproponowanego dwuetapowego podejścia łączącego minimalne drzewa rozpinające z autorską metodą selekcji, które tłumaczy ponad 90% dynamiki indeksu Nasdaq-100. Analiza zidentyfikowała istotne zmiany w topologii podczas globalnego kryzysu finansowego (rola CSCO jako firmy centralnej) oraz pandemii COVID-19 (wspólne ruchy akcji).
Emerging Links Between COVID-19 and Cardiovascular & Cerebrovascular Thromboembolic Events: A Systematic Review
Authors:   Epidemiological Cardiology Research Center, Section on Cardiovascular Medicine, Department of Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, Agarwal Abhimanyu , Panjiyar Binay K ,   Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA, Manishbhai Patel Dhwani ,   Smt. NHL Medical College, Ahmedabad, India, Ghotra Monica ,   Sri Guru Ram Dass Institute of Medical Sciences and Research, Vallah, Punjab, India, Nabi Husain Mahato Gulam Husain , Brijeshkumar Upadhyay Ronak ,   Nootan Medical College and Research Center, Visnagar, Gujarat, Indi
Published: September 2024

Purpose: COVID-19, caused by the SARS-CoV-2 virus, initially identified as a respiratory illness, has increasingly been linked to a broader range of organ complications. This systematic review explores the impact of COVID-19 on cardiovascular and cerebrovascular health, focusing on thromboembolic events in post-COVID patients. Method: A comprehensive literature search was conducted in PubMed and Google Scholar databases up to July 2023, utilizing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Studies meeting eligibility criteria were analyzed for outcomes and associations between COVID-19 and cardiovascular and cerebrovascular events. Result: The review includes 6 studies involving over 12 million patients, demonstrating a strong connection between COVID-19 and elevated risks of cardiovascular and cerebrovascular thromboembolic events. The risk of these events is evident in conditions such as ischemic heart disease, stroke, and cardiac arrhythmias. The burden of these events beyond the acute phase of the disease is concerning, warranting further exploration of long-term implications. Variability in event rates among different cohorts and healthcare settings underscores the need for understanding underlying factors influencing these differences. Potential mechanisms behind these events include endothelial dysfunction, systemic inflammation, and viral invasion. Implications for public health policies, clinical guidelines, and future research directions are discussed. Conclusion: This review serves as a valuable resource for healthcare providers, policymakers, and researchers to enhance patient care, outcomes, and preparedness for future waves of COVID-19 infections. However, there remain unexplored aspects of the COVID-19 and thromboembolic events relationship, urging further investigations into mechanistic insights and potential therapeutic interventions.
Post-COVID-19 Infection Tietze’s Syndrome in a Young Adult Patient
Authors: Mark Sayeef Hossain Khan , Khan Rasif Hossain , Mishu Shaima Rahman , Azad Khan Abul Kalam
Published: September 2024

Tietze syndrome is a benign inflammation of one or more of the costal cartilages. The condition is characterized by tenderness and painful swelling of the anterior (front) chest wall at the costochondral (rib to cartilage), sternocostal (cartilage to sternum), or sternoclavicular (clavicle to sternum) junctions. We describe a previously healthy 35 years old gentleman with repeated presentations to the emergency department (ED) with left-sided chest and sternoclavicular pain on a background of recent asymptomatic COVID-19 infection. Labs and imaging subsequently confirmed the diagnosis of Tietze’s syndrome. Anti-inflammatory medications and colchicine eventually led to uneventful recovery. This case highlights how Tietze’s syndrome — a disorder that is potentially self-limiting, can cause recurrent hospital admission and should be a differential diagnosis of chest pain related to COVID-19.
Bangladesh J Medicine 2023; 34(2): 155-159
A Deadly Tunnel: A Case Report of Atrial-Esophageal Fistula after Atrial Fibrillation Ablation
Authors: Hoque Farzana
Published: September 2024

The left atrial-esophageal fistula is an exceedinglyrare but lethal iatrogenic complication after atrial fibrillation ablation. Variability in timing of clinical presentation may lead to delayed diagnosis of this fatal complication. It is crucial to have high clinical suspicion when patients present with new neurologic symptoms, chest discomfort or sepsis after ablation. This is a unique case of 78-year-old white man who presented with fever, hematemesis & confusion attributed to left atrial-esophageal fistula after ablation for medically refractory atrial fibrillation.
Bangladesh J Medicine 2023; 34(2): 160-162
A Young Girl With Granulomatosis with Polyangiitis: A Rare Case Report
Authors: Rahman Md Mahfuzer , Roy Rana Shankor , Rabbani Md Golam , Banu Akter , Kabir Md Jahangir , Azad Md Abul Kalam , Akter Mohsina , Arafat Yeasir
Published: September 2024

Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis is a necrotizing vasculitides that primarily affects small-sized arteries and manifests differently depending on the organ involved and the severity of the disease. Here we are reporting a case of a 15-year-old girl presented with purulent nasal discharge with epistaxis, cough, reduced hearing, fever & rash. Tissue biopsy report, positive C-ANCA, imaging and clinical features were consistent with the diagnosis of GPA. After counseling the patient & her parents and taking consent, she has been treated with intravenous methylprednisolone and cyclophosphamide. Despite being a rare disease with a typical age of onset around 40 years, it should be suspected in any aged patient exhibiting constitutional symptoms and other evidence of upper or lower respiratory tract involvement or glomerulonephritis.
Bangladesh J Medicine 2023; 34(2): 151-154
Non Alcoholic Fatty Liver Disease: A Silent Global Epidemic
Authors: Shil Bimal Chandra , Uddin Mohammad Kamal , Hasan Monirul
Published: September 2024

Nonalcoholic fatty liver disease (NAFLD) is a common liver disease worldwide affecting adult as well as children with an increasing prevalence. It is associated with insulin resistance and frequently occurs with features of the metabolic syndrome. NAFLD is a spectrum, with NAFL (Non-alcoholic fatty liver) being the initial mildest form, NASH and cirrhosis is being at the other end of the spectrum. Mostly NAFLD is asymptomatic but may present with elevated liver enzyme levels to cirrhosis with its complications and hepatocellular carcinoma. Standard ultrasound including elastography may be used to detect steatosis. Though, liver biopsy is the gold standard for diagnosis of NAFLD but it is not frequently performed. NAFLD patients with evidence of nonalcoholic steatohepatitis and advanced fibrosis are at increased risk of adverse outcomes, including overall mortality.  Life style modification and weight loss remains the cornerstone of the management of NAFLD. There are no approved pharmacological drugs for the treatment of NAFLD till now. Although several promising drugs are on the horizon, more trials are needed to validate these medications.
Bangladesh J Medicine 2023; 34(2): 73-79
God Must Be Crazy
Authors: Islam Quazi Tarikul
Published: September 2024

Abstract not available
Bangladesh J Medicine 2023; 34(2): 171
Prevalencia de caries dental en niños de 6 y 12 años en un distrito de la provincia de Islay, Arequipa
Authors: Lavado García Mayra Isaura , Adasme Zeballos Jacqueline Judith
Published: September 2024

Objetivo: Determinar la prevalencia de caries utilizando los índices CEOD y CPOD y compararlos según las características sociodemográficas en niños de 6 y 12 años en un distrito de la provincia de Islay, Arequipa. Material y métodos: Estudio relacional, de corte transversal, prospectivo. Previo consentimiento informado de los padres, se realizó una revisión bucodental a 50 niños, utilizando los índices CEOD para niños de 6 años y CPOD para niños de 12 años, que participaron de un programa educativo en el año 2023. Estos datos fueron registrados en fichas individuales y luego procesados en el programa SPSS. Se utilizaron estadísticos descriptivos y la prueba Chi2 para el análisis. Resultados: Del total de niños, el 56 % fueron de sexo femenino y el 52 % presentaron 12 años. La prevalencia de caries fue alta en el 28 % y muy alta o moderada en el 22 %. Según el género, el 32,1 % de las niñas presentó alto índice de caries, siendo alta o moderada en un 21,4 %; mientras que, en los niños, en el 22,7 % fue moderada, alta o muy alta. Según la edad, en los niños de 6 años, la presencia de categorías baja, moderada, alto y muy alto fue del 25 % para todos los casos; mientras que, en los niños de 12 años la categoría alta fue la más frecuente en el 30,8 %. Conclusión: Al considerar las características sociodemográficas de los niños, no se encontraron diferencias significativas en la prevalencia de caries según género o edad.
DESIGNING TAX ME SERVICE APPLICATIONS IN TAX CONSULTING
Authors: Joosten Joosten , Halim Fandi , Arianto Jennifer , Yulinda Cindy
Published: September 2024

Abstract: "Tax Me" is an application engaged in tax consulting services that is run through a mobile platform. The problems that are often faced by the public, especially taxpayers, are difficulties in choosing reliable and trusted tax consultants because many tax consultants embezzle money and slow down the tax reporting process, as well as the lack of knowledge of taxpayers about all tax regulations, a complicated and frequently changing tax system, and also there are still negative public assumptions about taxes such as corruption in taxes that have been paid by taxpayers.  The "Tax Me" application was developed using the System Development Life Cycle (SDLC) system development methodology. This application was developed as a forum for tax consulting services in collaboration with the Directorate General of Taxes (DGT) institution which is able to provide transparent and reliable tax consulting services. "Tax Me" is expected to be able to provide education to taxpayers, overcome taxpayers' concerns about the tax calculation and reporting process as well as in choosing a tax consultant who can be trusted. In addition, several features of the "Tax Me" application such as: NPWP, Tax Calculation, Tax Consultation, Report & Check Annual Tax Return, E-Billing & Pay Tax, Tax Reminder and Tax Article.            Keywords: directorate general of taxes (DJP); tax; tax me; taxpayer  Abstrak: “Tax Me” adalah aplikasi yang bergerak pada bidang pelayanan konsultasi pajak yang dijalankan melalui platform mobile. Masalah yang sering dihadapi oleh masyarakat khususnya Wajib Pajak adalah kesulitan dalam memilih konsultan pajak yang dapat diandalkan dan dipercaya karena banyak konsultan pajak yang menggelapkan uang dan memperlambat proses pelaporan pajak, serta kurangnya pengetahuan Wajib Pajak mengenai segala peraturan perpajakan, sistem perpajakan yang rumit dan sering berubah, dan juga masih ada anggapan negatif masyarakat tentang pajak seperti korupsi atas pajak yang telah dibayarkan oleh Wajib Pajak. Aplikasi “Tax Me” dikembangkan dengan menggunakan metodologi pengembangan sistem System Development Life Cycle (SDLC). Aplikasi ini dikembangkan sebagai wadah layanan konsultasi perpajakan yang bekerja sama dengan lembaga Direktorat Jenderal Pajak (DJP) yang mampu memberikan layanan konsultasi perpajakan yang transparan dan terpercaya. “Tax Me” diharapkan mampu memberikan edukasi kepada Wajib Pajak, mengatasi kekhawatiran Wajib Pajak terhadap proses perhitungan dan pelaporan pajak juga dalam memilih konsultan pajak yang dapat di percaya. Disamping itu, beberapa fitur dari aplikasi “Tax Me” seperti: NPWP, Hitung Pajak, Konsultasi Pajak, Lapor & Periksa SPT Tahunan, E-Billing & Bayar Pajak, Pengingat Pajak dan Artikel Pajak. Kata kunci: direktorat jenderal pajak (DJP); pajak; tax me; wajib pajak
MAPPING SYSTEM FOR LOCATION OF STUNTING CASES IN TODDLER IN TANJUNG BALAI CITY USING WEBGIS
Authors: Alfa Zikri , Yusda Riki Andri , Rahayu Elly
Published: September 2024

Abstract: Data on stunting cases among toddlers in Datuk Bandar Timur sub-district, Tanjung Balai city Not yet processed in a way computerized use digital map , so that the monitoring process in-depth investigation of the distribution and patterns of stunting in a area Not yet presented with Good . This matter Of course impact on cadre Public health center Semula Jadi For monitor number nutrition bad And spread prevalence of stunting in Datuk Bandar Timur sub-district, Tanjung Balai city . For That need development A system internal data management form chart nor map that can be give description spread nutrition bad in the region Mayor. Planning And development system information This done with use method data collection and interview direct to the UPTD Community Health Center Semula Jadi . Objective it was built this webgis can assist in identifying areas that need nutritional intervention, mapping the prevalence of stunting and malnutrition, as well as monitoring nutrition programs and optimizing resource allocation. Results from GIS can plays an important role in supporting efforts to prevent and overcome stunting problems by providing tools effective software for collecting, analyzing and visualizing nutritional data spatially. The use of web GIS can also provide information on stunting locations from UPTD Semula Jadi Health Center data.Keywords : geographic information system; location mapping system; stunting.  Abstrak: Data kasus stunting pada balita di kecamatan datuk bandar timur kota tanjung balai belum diproses secara terkomputerisasi menggunakan peta digital, sehingga proses pemantauan penyelidikan mendalam tentang sebaran dan pola stunting disuatu daerah belum tersajikan dengan baik. Hal ini tentu berdampak pada kader puskesmas Semula Jadi untuk memantau angka gizi buruk dan penyebaran prevalensi stunting di kecamatan datuk bandar timur kota tanjung balai. untuk itu perlu pembangunan sebuah sistem pengelolaan data dalam bentuk grafik maupun peta yang dapat memberikan gambaran penyebaran gizi buruk diwilayah Datuk Bandar. Perancangan dan pembangunan sistem informasi ini dilakukan dengan menggunakan metode pengambilan data dan wawancara langsung ke UPTD Puskesmas Semula Jadi. Tujuan dibangunnya webgis ini dapat membantu dalam identifikasi daerah yang membutuhkan intervensi gizi, pemetaan prevalensi stunting dan gizi buruk, serta memantau program-program gizi dan optimalisasi alokasi sumber daya. Hasil dari SIG dapat berperan penting dalam mendukung upaya pencegahan dan penanggulangan masalah stunting dengan menyediakan alat software yang efektif untuk pengumpulan, analisis, dan visualisasi data gizi secara spasial. Kegunaan webgis juga dapat memberikan informasi mengenai lokasi stunting dari data UPTD Puskesmas Semula Jadi.Kata kunci: sistem informasi geografis; sistem pemetaan lokasi; stunting
Patients-Reported Outcomes of Acute Side Effects During Head and Neck Cancer Radiotherapy: A Cross-Sectional Study at Andalas University Hospital Padang
Authors: Ismail Fikri Wahyuda , Rafli Rhandyka , Putriyuni Anandia
Published: September 2024

Background: Head and neck cancer is a malignancy originating from the upper aerodigestive tract. Head and neck cancer patients undergoing radiotherapy using brachytherapy, 2DRT, 3CDRT, and IMRT techniques. Patients undergoing radiotherapy will experience several acute side effects consisting of mucositis, dysphagia, xerostomia, and dermatitis. This is influenced by the technique and dose given. This study aims to grade and time the acute side effects of radiotherapy for head and neck cancer at the Andalas University Hospital Padang. Methods: A quantitative descriptive method with a cross-sectional approach is used. Secondary data with a total sample of 88 patients. This research uses medical record data and is analyzed using statistical analysis methods. Results: This study found that the most head and neck cancer patients who underwent radiotherapy were male 57 (64.8%) patients, nasopharyngeal subsite 41 (46.6%) patients with non-keratinizing nasopharyngeal carcinoma 32 (36.4%) patients. The most common radiotherapy technique for head and neck cancer was IMRT in 58 (65.9%) patients with a dose of 61-70 Gy in 78 (88.6%) patients and the most common stage was IV A in 51 (58%) patients. Patients did not undergo chemotherapy treatment in 51 (58%) and surgery in 69 (78.4%). Body mass index (BMI) before radiotherapy was normal in 74 (84.1%) patients and after radiotherapy became underweight in 57 (64.8%) patients resulting in weight loss 1 kg in 83 (94.3%) patients. The highest grade of radiotherapy side effects was grade 1 which consisted of mucositis 84 (95.5%), dysphagia 83 (94.3%), xerostomia 78 (88.6%), and dermatitis 78 (88.6%) patients. The most frequent timing of mucositis side effects occurred in the 3rd week in 40 (45%) patients, dysphagia in the 3rd week in 41 (47%) patients, xerostomia in the 3rd week in 33 (38%) patients, and dermatitis at week 6 in 24 (27%) patients. Conclusions: Patients with head and neck cancer who undergo radiotherapy from week 1 to week 7 will experience side effects, including mucositis, dysphagia, xerostomia, and dermatitis. The average side effect appears in the 3rd week with grade 1.
Descriptive Analysis of CT Scan Findings in Breast Cancer Patients with Bone Metastases in Universitas Andalas Hospital Radiotherapy Installation
Authors: Yusriono Irfan , Tri Septiana Vina , Rafli Rhandyka
Published: September 2024

Background: Breast cancer is experiencing the most significant increase in cases among all cancers worldwide. Approximately 65% to 75 % of advanced breast cancer patients will experience bone metastases. CT scan is the most affordable and accessible method for evaluating bone metastases. This study aims to describe the characteristics of CT scan examination of bone metastases in breast cancer patients in the radiotherapy installation at Universitas Andalas Hospital from 2019 until 2021. Methods: A total of 51 patients with breast cancer who had bone metastases were included in this quantitative descriptive study, using a total sampling approach. The clinical data was taken from the medical records at the radiotherapy installation at Andalas University Hospital. The collected data was processed and analyzed using SPSS statistical software. Results: Based on the results, the mean age of patients was 49 years. The most histopathological type was invasive carcinoma mammae of no special type (57%). The most common site for bone metastases is osteo vertebrae (35%). Mixed lesions were the most frequent bone metastatic finding (51%), with fractures occurring in 27% of cases. Conclusions: The results of this study are breast cancer with bone metastases occurring on average at the age of 49 years, histopathological type the most is invasive carcinoma mammae of no special type. Breast cancer with bone metastases is most common in Osteo Vertebrae with mixed lesions as well as pathological fracture with a low percentage.
Finansal Teknolojik (FinTek) Gelişmeler Türkiye’de Enflasyonu Etkiliyor mu?
Authors: Kömürcüoğlu Ömer Faruk
Published: September 2024

Finansal teknolojiler alanında yaşanan gelişmeler geçmişte olduğu gibi günümüzde de bankacılık ve finans sektörünü etkilemektedir. Finansal teknolojiler, çağın gereklerine uygun ürün ve hizmetleri ucuz ve etkili bir şekilde sunarak daha fazla ilgi çekebilmektedir. Bu ilgi olumlu görülse de ödeme hizmetlerinde alternatifler yaratarak hanehalkı harcama alışkanlıklarını değiştirmesi ve artırması enflasyonist baskı doğurabileceği için politika yapıcılar tarafından dikkatle izlenmesi gerekmektedir. Çalışmanın amacı, Türkiye’de 2012:Q1-2023:Q1 dönemi için finansal teknolojik gelişmelerin enflasyona etkisini incelemektir. Finansal teknolojik gelişmeleri temsilen beş farklı değişken kullanılarak “FinTek Endeksi” oluşturulmuştur. Elde edilen bulgular, Türkiye’de finansal teknolojik gelişmelerin uzun dönemde enflasyonu artırdığını göstermiştir. Toda-Yamamoto nedensellik testi sonuçlarına göre değişkenler arasında karşılıklı nedensellik ilişkisi saptanmıştır.