bluuebunny/crossref_metadata_2025 huggingface dataset:
EXISTENTIAL MERCY AS A VALUE-SEMANTIC REGULATION OF THE ACTIVITIES OF WAR
CORRESPONDENTS
Authors: Kolobova S. V. , Maligina E. V.
Published: September 2024

In order to study such a phenomenon as existential mercy in the context of
value-semantic regulation regarding the activities of war correspondents, the work
analyzes the work of researchers in the field of psychology and sociology on the problem
of existential mercy as value-semantic regulation. It is shown that developed value
orientations within the framework of existential mercy help people maintain emotional
balance, prevent burnout, be aware of their emotions and fears, find the strength to
continue working and maintain professional integrity. A high level of existential mercy
contributes to the strengthening of professional activity and adaptation to stressful
situations of war correspondents. Existential mercy contributes to the formation of
emotional and psychological stability, which is an important factor for maintaining the
physical, psychological and mental health of war correspondents.
THE CONCEPTOSPHERE OF THE NOVGOROD TEXT: TO THE PROBLEM STATEMENT
Authors: Tereshkina D. B. , Kniazeva T. S.
Published: September 2024

The purposr of the article is to provide a preliminary analysis of the main
problems and questions regarding the construction of a model of the conceptosphere of
the Novgorod text in Russian literature. The conceptosphere of local texts has recently
been the subject of considerable research, with each specific locus applying the model
of a "collection of concepts" (defined by D.S. Likhachev, who introduced the
term "conceptosphere") in a unique variant specific to that locus. However,
the scientific validity of the model is justified not only by the support of precedent
texts of local literature but also by the universal nature of approaches to describing
the conceptosphere of a local text, regardless of the chosen locus of study. This
universal model includes the concepts of a nuclear (basic) concept, a nominative field
of concepts, the center and periphery of semantic fields of concepts in a local text,
their hierarchically organized system (conceptosphere) and others. The Novgorod text
requires the construction of a model of its conceptosphere as one of the most enriched
local texts in Russian literature.
Multifactorial Methodology of Assessment of Socio-economic Efficiency of Management Consulting
Authors:   Immanuel Kant Baltic Federal University, Pavlyak V. E.
Published: September 2024

In this article, the author researches the problem of assessment of socio-economic ef-ficiency of management consulting services, which is becoming more and more actual within the growing industry. Despite the visible increase of consulting projects affecting regional socio-eco-nomic development, it is still complicated to measure it due to existing methodological problems and limitations including difficulties with counting all the factors influencing regional changes, especially long-term ones, and diversity of consulting services, which complicates creation of standardized tool set for the assessment of their efficiency. The author analyzes key issues of existing approaches and suggests common methodological principles as a fundament for build-ing a universal method of assessment, which covers different types of consulting services and clients. Moreover, it is suggested to use a new terminology for defining different combinations ofdifferent types of efficiency of consulting projects. The core result of this work is the FESG meth-odology that covers financial, ecological, social, and governmental components of efficiency. The methodology is described together with its limitations, conditions, and practical guidance on its usage with examples. The methodology is offered to consulting companies to assess their pro-jects before and after the implementation. If assessing before, it helps to weigh main advantages and disadvantages, and take the decision whether to sign for the project. After the implementation it helps to confirm the value of the project and position this consulting company as a social impactor meaning it might be used as an element of marketing. This methodology is also helpful for regional governance and any researcher assessing the impact of consulting com-panies on regional socio-economic development.
ESTIMATION OF HYDROXYCINNAMIC ACIDS CONTENT IN BERRY FRUITS
Authors: Миронов А.М. , Акимов М.Ю. , Кольцов В.А. , Жидехина Т.В. , Брыксин Д.М. , Хромов Н.В.
Published: September 2024

Продукция с  высоким содержанием гидроксикоричных кислот благотворно воздействует на  здоровье человека. В  связи с  этим возрастает научный интерес к  оценке содержания гидроксикоричных кислот в  плодах ягодных культур. Количественное определение гидрокискоричных кислот проводили с  помощью метода обращенно-фазовой высокоэффективной жидкостной хроматографии. В качестве стандартов использовали: хлорогеновую кислоту (Fluka), кофейную кислоту (Fluka), para-кумаровую кислоту (Sigma), тrans-коричную кислоту (Aldrich), цикориевую кислоту (Sigma), тrans-феруловую кислоту (Sigma). Объектами исследования служили плоды различных сортов ягодных культур (жимолость, ирга, кизил, крыжовник, малина, смородина красная, смородина черная). Наиболее высоким содержанием хлорогеновой кислоты характеризовались плоды смородины черной сортов Тамерлан (64,29  мг/100  г) и  Чернавка (61,89  мг/100  г), кофейной кислоты  — смородины черной сорта Зеленая дымка (9,36 мг/100 г), р-кумаровой кислоты — смородины черной сорта Тамерлан (8,41 мг/100 г), цикориевой кислоты  — кизила сорта Аббат (1,23  мг/100  г), транс-феруловой кислоты  — крыжовника сорта Kuršu Dzintars (0,89  мг/100  г), т-коричной кислоты  — кизила сорта Волгоградский грушевидный (1,03 мг/100 г).

Products with a  high content of  hydroxycinnamic acids have beneficial effects on  human health. In  this regard, scientific interest in the evaluation of hydroxycinnamic acids content in  berry fruits is  increasing.Quantitative determination of  hydroxycinnamic acids was carried out using reversed-phase high-performance liquid chromatography. Chlorogenic acid (Fluka), caffeic acid (Fluka), para-coumaric acid (Sigma), tranes-cinnamic acid (Aldrich), cichoric acid (Sigma), tranes-ferulic acid (Sigma) were used as standards. Fruit of berry crops (honeysuckle, honeysuckle, honeysuckle, cotoneaster, gooseberry, raspberry, red currant, black currant) served as objects of the study. The highest content of chlorogenic acid was observed in black currant fruits of Tamerlan (64.29 mg/100 g) and Chernavka (61.89 mg/100 g) varieties, caffeic acid — in black currant fruits of Green Smoke variety (9.36  mg/100  g), p-coumaric acid  — black currant fruits of Tamerlan variety (8.41 mg/100 g), cichoric acid — in kizil Abbat berries (1.23  mg/100  g), trans-ferulic acid — gooseberry fruits of  Kuršu Dzintars variety (0.89  mg/100  g), t-cinnamic acid  — Volgograd pear-shaped kizil (1.03 mg/100 g).
ASSESSMENT OF STRAWBERRY SELECTED FORMS BY RESISTANCE TO RED STELE ROOT ROT (RPF1 GENE)
Authors: Лыжин А.С. , Лукъянчук И.В.
Published: September 2024

Показаны результаты анализа аллельного состояния гена Rpf1  устойчивости к  фитофторозной корневой гнили у  гибридных форм земляники селекции «ФНЦ им. И.В. Мичурина». Аллель rpf1 в гомозиготном состоянии (восприимчивость к фитофторозу) идентифицирован у сеянцев 932-29 (F. virginiana subsp. platypetala × Фейерверк), 933-4 (F. virginiana subsp. platypetala × Рубиновый кулон), 62-7, 62-23 (Былинная × Фейерверк), 65-2, 65-15 (Олимпийская надежда × Былинная), 35-16 (922-67 × Maryshka). Гетерозиготное сочетание аллелей гена Rpf1  выявлено у  гибридных сеянцев 69-29 (Фейерверк × Былинная), 62-41 (Былинная × Фейерверк), 72-24, 72-71 (Привлекательная × Былинная), 65-17, 65-24 (Олимпийская надежда × Былинная), что позволяет использовать их в селекции на устойчивость к P. fragariae var. fragariae в качестве ценных исходных форм.

The results of  the analysis of  allelic state of the Rpf1 red stele root rot resistance gene in strawberry hybrid forms created in  the “I.V. Michurin FSC” were shown. Allele rpf1 in homozygous state (susceptibility to red stele root rot) was identified in  strawberry seedlings 932-29 (F. virginiana subsp. platypetala × Feyerverk), 933-4 (F. virginiana subsp. platypetala × Rubinovyy kulon), 62- 7, 62-23 (Bylinnaya × Feyerverk), 65-2, 65-15 (Olimpiyskaya nadezhda × Bylinnaya) and 35-16 (922-67 × Maryshka). Heterozygous combination of Rpf1 gene alleles was identified in  strawberry hybrids 69-29 (Feyerverk × Bylinnaya), 62-41 (Bylinnaya × Feyerverk), 72-24, 72-71 (Privlekatelnaya × Bylinnaya), 65-17, 65-24 (Olimpiyskaya nadezhda × Bylinnaya), which allows them to  be  used in  breeding for resistance to  P. fragariae var. fragariae as valuable initial forms.
ECOLOGICAL ASSESSMENT OF HYBRID SEEDLINGS RED CURRANTS
Authors: Родюкова О.С.
Published: September 2024

Проведена оценка гибридных сеянцев, полученных от  свободного опыления сортов смородины красной. Высокий выход сеянцев, устойчивых к  абиотическим стрессорам получен в гибридном потомстве сортов Голландская розовая, Герой, Джонкер ван Тетс, устойчивых к  антракнозу: Герой, Голландская розовая, Память Смольяниновой, устойчивых к листовой галловой тле: Виксне, Голландская розовая, Джонкер ван Тетс, Память Смольяниновой. Выделены перспективные формы с высоким уровнем хозяйственно-ценных признаков.

High yield seedlings that are resistant to abiotic stressors was obtained in  hybrid progeny from free pollination of cultivars of Gollandskaya rozovaya, Geroyi, Jonkeer van Tets, resistant to anthracnose: the Geroyi, Gollandskaya rozovaya, Pamyat` Smol`yaninovoy, resistant to leaf gall aphids: Viksne, Gollandskaya rozovaya, Jonkeer van Tets, Pamyat` Smol`yaninovoy. Promising selected forms with a high level of economically valuable features are identified.
RELATIONSHIP OF COMPONENT COMPOSITION OF SUPERCRITICAL CO2 EXTRACTS OF WILD CARROTS WITH GROWING CONDITIONS
Authors: АЛИЕВ А. М. , РАДЖАБОВ Г. К. , ВАГАБОВА Ф. А. , ИСЛАМОВА Ф. И. , ГОРЯИНОВ С. В. , ХАЖЖАР Ф. ХАЖЖАР Ф. , ХАММАМИ С. ХАММАМИ С.
Published: September 2024

Для изучения влияния экологических условий произрастания на химический состав растений проведена сверхкритическая углекислотная экстракция образцов моркови дикой Daucus carota subsp. maritimus, широко распространенной во всех регионах мира с умеренным климатом. С использованием методов газо-жидкостной хроматографии и масс -спектрального анализа в полученных экстрактах были определены летучие органические соединения, жирные кислоты и фитостерины находящиеся в изучаемых объектах. Показана зависимость химического состава моркови дикой от условий ее произрастания (температура, осадки, солнечная радиация и т. п.).

To study the influence of ecological growing conditions on the chemical composition of plants, supercritical carbon dioxide extraction of wild carrot samples, widespread in all regions of the world with a temperate climate (Daucus carota subsp. maritimus). Using the methods of gas-liquid chromatography and mass spectral analysis, volatile organic compounds, fatty acids and phytosterols in the studied objects were determined in the extracts obtained. The dependence of the chemical composition of wild carrots on its growing conditions (temperature,precipitation,solar radiation,etc.) is shown.
Analysis of Essential Oils Extracted from Algerian Medicinal Plants and Their Aphicidal Effect Against the Melon Aphid Aphis Gossypii Glover (Homoptera: Aphididae)
Authors: Hakimi Sakina , Araj Salah-Eddin , Ateyyat Mazen A. , Bounechada Mustapha , Demirtas Ibrahim , Gul Fatih
Published: September 2024

Chemical insecticides are decisive in controlling insect pests, but they harm the environment. Reducing the use of chemical insecticides has become the main goal for ensuring healthy produce. However, research focusing on plant-based compounds has recently increased. The present study was carried out to analyze essential oils extracted from Algerian medicinal plants by gas chromatography coupled with mass spectrometry (GC-MS) to determine the insecticidal activity of essential oils from Juniperus phoenicea, Rosmarinus officinalis, Lavandula stoechas, Mentha pulegium and Pinus sylvestris, against Aphis gossypii Glover The main components constituting each essential oil were: α-pinene, β-Pinene 1,8- cineol, Linalool, Linalyl acetate, Fenchone, Pulegone, and Camphor. The toxicity of tested essential oils against Aphis gossypii was different and dependent on the concentration used (1000, 10000, and 100000 ppm), the duration of exposure (24, 48, and 72 h), and the chemical composition of the oil. The highest toxicity was for J. phoenicea, M. pulegium, and L. stoechas which were toxic as Actara® insecticide.
Impact of Hybrid Varieties on the Productivity of Rice Cultivation: The Case of Sindh, Pakistan
Authors: Abbasi Saqib
Published: September 2024

Agriculture is a very important sector and crucial for poverty reduction and employment generation. The use of hybrid seeds leading to increased yield of crops and farmers’ income has been widely discussed in the literature. Through this study, an effort has been made to identify factors that impact obtaining high crop yield of rice by using the hybrid varieties. This study focuses on the use of hybrid varieties in the rice crop and presents a comparison in yield with the traditional open-pollinated varieties.  The plot level information collected from eight major rice-producing districts of Sindh province of Pakistan was used to conduct this study and a propensity score matching technique was used to estimate the results of the study by using plot level variation between hybrid varieties and open-pollinated varieties. The results of the study showed significant improvement in rice yield with the adoption of hybrid rice varieties in the study area.  This study highlights that the farmers have achieved a higher average yield of rice by using hybrid seeds as compared to open-pollinated varieties. Besides the crop yield, the overall income and profit of farmers have also increased by using hybrid seeds in the Sindh province. The study illustrates different interesting patterns relating to different characteristics of the household cultivating rice crops, different plot-level characteristics, and their comparison with hybrid and traditional varieties.
El cuadro endometral en las hemorragias uterinas funcionales
Authors:   , Guixa Héctor Lucio
Published: September 2024

La metropatía hemorrágica es una afección frecuente, que se encuentra fundamentalmente en dos etapas de la vida genital de la mujer: al comienzo, es decir, la pubertad, y al finalizar, la premenopausia, hecho lógico si se tiene presente que se trata en último término de una manifestación de deficiencia ovárica. En el primer caso se trataría de un ovario que no ha llegado aún a su madurez y en el segundo, el agotamiento después de muchos años de funcionamiento. De ahí que se la haya dividido en 2 formas fundamentales: la juvenil (o de R. Meyer) y la premenopaúsica (o de K. Schroeder). La primera a su vez puede subdividirse en puberal (pacientes de 11 a 20 años) y Juvenil propiamente dicha (de 21 a 34 años), considerando la forma premenopausica por encima de los 35 años. Constituye a veces problemas terapéuticos de gran importancia, y ha sido objeto de múltiples trabajos, pero pocos Son los que se refieren a un aspecto nuevo sobre el que se ha insistido en los últimos años, cual es al variado tipo histológico del endometrio que descama. Esto es lo que nos ha inducido a presentar como tesis de profesorado un estudio de conjunto del problema, actualizando al mismo tiempo el tema por considerarlo de importancia.
The Effect of Product Attributes, Brand Image, and Variety Seeking on Brand Switching of Lemonilo Instant Noodles
Authors: Wiyoko Achmad Jauhar , Transistari Ralina
Published: September 2024

This study aims to analyze the effect of product attributes, brand image, and variety-seeking behavior on brand switching from other brands to Lemonilo instant noodles. This research is quantitative, utilizing a non-probability sampling method and purposive sampling technique. The sample size of this study consists of 100 respondents. The analytical method used is multiple linear regression analysis. Research results show that product attributes, brand image, and variety seeking have a positive effect on brand switching from other brands to Lemonilo instant noodles.
Small Business Empowerment Strategy in the Agricultural Sector Through Digital Entrepreneurship
Authors: Achmad Adnan , Karto Andriani , Asril Akmil
Published: September 2024

This study looks at how digital entrepreneurship is being used by small enterprises in the agriculture industry to empower them. It focusses on how this is affecting market access, production efficiency, and bolstering competitiveness. The advent of digital transformation has presented small enterprises with novel prospects to surmount customary constraints, including restricted availability of markets, finance, and technology. This research employs a qualitative methodology and a case study approach to investigate how small agricultural firms might use digital technologies, like e-commerce platforms and the Internet of Things (IoT), to increase market access and productivity. In-depth interviews with small business owners, technology suppliers, and other stakeholders were used to gather data. Direct observation and document analysis were also used. The results of this study show that small enterprises' operational efficiency and revenue are greatly increased when digital entrepreneurship is implemented. Collaboration with a range of stakeholders, including the government and academic institutions, and sufficient digital literacy have shown to be crucial for the effective execution of this plan. This study also emphasises how crucial it is to create both domestic and global business networks in an effort to increase market penetration and boost the competitiveness of small enterprises in the agriculture industry. In order to increase the sustainability and competitiveness of small enterprises in the agriculture sector, this study makes recommendations based on its results for policy makers and industry participants to assist the widespread adoption of digital entrepreneurship.
Effective Digital Business Management Strategy: A Structured Approach to Turning Challenges into Opportunities for Sustainable Growth and Innovation
Authors: Rasyad Rizky Zakariyya , Nuraini Mawardah Putri
Published: September 2024

Digital transformation has become one of the main pillars of modern business strategy, requiring companies to adapt to technological developments and maximize emerging opportunities. This article explores effective digital business management strategies, focusing on a structured approach to transform challenges into opportunities for growth and sustainable innovation. Through a qualitative approach based on literature studies and case analysis, this study identifies key elements in digital business management strategies, including the use of information technology (IT) and management information systems (MIS), the use of data and analytics, organizational flexibility, continuous innovation, and strategic collaboration with external parties. The results show that companies that successfully implement this strategy can adapt quickly to market changes, improve operational efficiency, and create competitive advantages. Flexibility and continuous innovation are also found to be important factors in ensuring business continuity amidst technological disruption. In addition, collaboration between companies, startups, and academic institutions is a key element in driving innovation and optimizing resources. This article contributes to the academic literature and business practice, by offering practical guidance for companies to formulate superior digital strategies in the era of global competition.
A PROSPECTIVE STUDY OF OPEN INGUINAL HERNIA REPAIR UNDER GENERAL/ SPINALANESTHESIA USING LOCAL INFILTRATION WITH SENSORCAINE 0.5%
Authors: A. Saiyed Aliyabanu , Jyoti Banerjee Divya , Parmar Anit , Kolsawala Hussain , Desai Ashish
Published: September 2024

Inguinal hernia repair is a common surgery aiming to minimize recurrence, pain, and cost. Studies explore techniques to achieve these goals.
Lichtenstein Tension-Free repair uses mesh to strengthen the abdominal wall, allowing for wider use of local anesthesia, reducing pain, shortening
recovery time, and lowering recurrence rates. Local anesthesia offers several benets: it's simple, safe, provides extended pain relief, allows early
mobilization without side effects, and is cost-effective. Inltrating the wound with local anesthetic is a proven method for pain control in various
surgeries with minimal complications. Local anesthetic toxicity, wound infection, and healing are not major concerns. This review summarizes
existing research on local anesthesia use in specic procedures and advocates for its wider adoption. Careful and controlled inltration of all tissue
layers is crucial. Local anesthetic nerve blockade is the most effective pain relief method, and its effects can last longer than the pain itself.
However, intermittent intramuscular opioids remain the common pain management approach despite their drawbacks. Techniques like epidural
catheters and wound inltration have demonstrably reduced post-surgical pain, opioid use, and respiratory complications. Studies comparing
wound inltration with inguinal nerve blocks after hernia repair show both methods provide excellent pain relief, as does intermittent local
anesthetic infusion into the wound. None of these methods have been linked to delayed wound healing, increased infection, or signs of sensitivity
CASE REPORT: AN UNUSUAL CAUSE OF RENAL COLIC
Authors: Gnanasekaran Pritika
Published: September 2024

A 58 year old diabetic woman presented with right sided renal colic and dysuria for one week. She had no prior history of haematuria. No past
medical history of hypertension, ischemic heart disease, Nephropathies or NSAID use. Laboratory investigations revealed a total white count was
elevated to 11.400 cells/cumm, USG abdomen showed mild right sided hydronephrosis secondary to right distal ureteric calculus obstruction.
Autismeconversietherapie
Authors: Springveld Niels
Published: September 2024

This article is the fourth installment in a series on the history of autism in the United States. This part focuses on psychologist Ole Ivar Lovaas and the history of applied behavior analysis (ABA).
Ervaringen van ouderen met het krijgen van de diagnose autisme
Authors: Quartel Annemarije , Andrea Helena , Wilting Rosalien , Videler Arjan
Published: September 2024

The experiences of ten older adults, who received their autism diagnosis later in life (after the age of 55), were acquired through semi structured interviews. The interviews were coded with the use of thematic analysis. The results show that older autistic adults often had a long history in mental healthcare, where autism was overlooked. The participants were relieved to have an explanation for their symptoms; however, they regretted not getting the diagnosis earlier in life. They were content about the treatment they received, after their diagnosis and about sharing experiences with like-minded people of their age. The participants had felt different from other people their entire life and had suffered from several psychological problems. For future research, it is recommended to study the experiences of a broader group of older adults who received their autism diagnosis in late life.
Muzisch-ludisch waardenwerk van humanistiekstudenten
Authors: Schreurs Martien
Published: September 2024

Als er ergens een plek op de wereld is waar je mag verwachten dat studenten betrokken zijn op hun studie en dat zij zich engageren met de samenleving waarin zij leven, dan is het wel de Universiteit voor Humanistiek die er in haar eigen woorden naar streeft om ‘een zinvol leven in rechtvaardige en zorgzame instituties’ te realiseren. Toch moet dit ideaalbeeld wel genuanceerd worden. Hoewel onze universiteit inderdaad een unieke plek inneemt in de academische wereld, heb ik mij in mijn lange ervaring als humanistiekstudent en -docent vaak verwonderd over de studiecultuur op onze universiteit. Wat ik mis, is echte betrokkenheid bij de studie. Ik merk bijvoorbeeld dat mijn studenten weinig lezen en dat ze vaak onvoorbereid naar de colleges en werkgroepen komen. Natuurlijk heeft dit met de veranderende mediatijd te maken, maar daarmee is het laatste woord nog niet gezegd. Ook al is het waar dat de huidige studenten andere media tot hun beschikking hebben dan de boeken, tijdschriften en kranten waardoor wij ons laten vormen, dan nog blijf ik zeggen dat onze studenten te weinig lezen en dat dit zorgelijk is. Ik zie bijvoorbeeld bijzonder weinig studenten die het belangrijk vinden om kwaliteitskranten te lezen. Ik maak mij daar zorgen over, ook omdat er geen geheugen is waar je als docent bij aan kunt haken. Zo kreeg ik onlangs van meerdere tweede jaar studenten te horen dat ze nog nooit van Adolf Eichmann gehoord hadden toen ik dit jaar een college gaf over banaliteit van het kwaad van Hannah Arendt. En onlangs was ik met stomheid geslagen toen een van onze masterstudenten tegen mij zei dat ze nog nooit van de schrijver Salman Rushdie gehoord had toen ik haar naar aanleiding van een specifieke gebeurtenis -terroristische aanslag- aanraadde om zijn laatste boek Knife te gaan lezen. De reden waarom ik zo verbaasd was, is dat zij een serieuze studente is die graag boeken leest. En dan merk ik weer dat onze studenten geen intellectuele oriëntatie hebben. Overigens ben ik wel de laatste docent die mijn ongeletterde studenten in verlegenheid wil brengen door bijvoorbeeld tegen hen te roepen dat het een schande is dat zij de grote literaire humanisten van de Europese humanistische traditie niet kennen. Mijn vraag is eerder hoe het zo ver heeft kunnen komen. Waarom lezen mijn studenten zo weinig essays en romans die tot de wereldliteratuur worden gerekend?
Transitional Home in Perspective: A Critical Overview of Burial Practices and Grave Construction among the Hausa of Northern Nigeria
Authors: Jabbi Umar Muhammad , Bawa Abubakar
Published: September 2024

Throughout history, the Hausa people of Northern Nigeria have viewed death as a transition from one form of existence to another. This belief underscores the importance of constructing elaborate structures to house their dead, providing for their needs during their 'everlasting sleep,' which is believed to last for centuries or even millennia. The deceased were often interred with various goods, signifying their social status within the community. The advent of Islam introduced clear and uniform guidelines for the disposal of the dead and other funeral practices. However, significant personalities in society continue to have their 'transitional homes' elaborately built. These 'transitional homes' are well-maintained, featuring plants and trees, and receiving regular upkeep. They are considered an integral part of the human community. This paper examines the belief system, funeral practices, and grave construction among the Hausa people to understand how these elements influence the conception of a 'transitional home' for the dead. The study draws on extensive literature reviews, observations, and discussions with cemetery custodians. This approach aims to illuminate the notion that transitional homes are seen as part of the human community, necessitating construction, frequent visits, protection, and care.
Evaluation of the Efficiency of Neural Enolase (NSA) in the Diagnosis of Viral Encephalitis: A Medical Review
Authors: Marchiori Carlos Henrique , Santana Marco Vinícios de Oliveira , Malheiros Klebert de Paula
Published: September 2024

Encephalitis is an inflammation that occurs in the brain when a virus in some cases, bacteria attack it directly, and can also be triggered by other factors. It is an inflammatory process of the meninges, the membranes that cover the central nervous system. Enolase isoenzyme found in neuronal and neuroendocrine tissues. Its levels in tissues other than erythrocytes are negligible. Its measurement is useful for monitoring tumors of neuroendocrine origin, such as neuroblastoma, pheochromocytoma, medullary thyroid carcinoma, small cell lung carcinoma, melanoma, and some pancreatic tumors. NSE concentrations in cerebrospinal fluid (CSF) are often elevated in diseases that result in relatively rapid neuronal destruction. This review aims to evaluate the efficiency of neural enolase (NSA) in diagnosing viral encephalitis. The methodology used an integrative literature review and a synthesis process to develop the study, expand the understanding of knowledge, and achieve the expected results. The integrative literature review is a method that aims to synthesize results obtained in research on a topic or issue, in a systematic, ordered, and comprehensive way. It is called integrative because it provides broader information on a subject/problem, thus constituting a body of knowledge. To carry out the study, a search for scientific articles was carried out through the Virtual Health Library, in the SCIELO, LILACS, and PUBMED databases, using the terminologies registered in the Health Sciences descriptors, encephalitis, enolase, virus, and diagnosis.
CHIA SEEDS: Novel Considerations in Therapeutics
Authors: Murad Shah , Yousaf Iftekhar , Lashari Saleemullah , Zainab Nikhar , Saifuddin Seema , Sharif Imtenan , Sangi Sibghatullah , Azad Abrar Hussain
Published: September 2024

In this study we evaluated and compared hypolipidemic efficacy of chia seeds and niacin. The study was conducted at National hospital, Lahore Pakistan from August 2019 to December 2019. Ninty hyperlipidemic patients were selected from cardiology and medical wards of the hospital. They were divided in three groups, one on placebo, another on chia seeds and third one on Niacin. After one and half month, significant changes (p value ranging from <0.05 to <0.001) were observed in their FBS, LDL and HDL-cholesterol. Conclusion of the study was to recommend use of chia seeds and Niacin for prevention and treatment of diabetes mellitus type 2 and secondary hyperlipidemia with good patient compliance.
Characteristics of Venomous Coleopterans and Their Venom with Therapeutic Power (Insecta: Coleoptera)
Authors: Marchiori Carlos Henrique , Santana Marco Vinícios de Oliveira , Malheiros Klebert de Paula
Published: September 2024

The medical importance linked to these beetles is because they have a terpene in their hemolymph insect blood that is soluble in various organic solvents, but practically insoluble in water, cantharidin. Only synthesized male cantharidin is stored until mating and transferred to the female at the time of copulation. When molested, these insects expel the toxin through the membranous joints of the body, causing vesicles similar to burns on human skin. Meloid beetles generate a poisonous chemical compound to, among other things, defend themselves from their predators. An international research team involving the Complutense University of Madrid has shown that cantharidin is toxic to several common parasites. The results explain that some birds, such as the great bustard, ingest this type of beetle, among other beneficial properties, due to the antiparasitic activity of cantharidin. The objective of this manuscript was to describe the characteristics of venomous coleopterans and their venom with therapeutic power (Insecta: Coleoptera). This is a narrative review of the literature, which is indicated to explain and discuss a certain subject from a theoretical or contextual perspective, in a to allow the reader to acquire and/or update knowledge on a specific topic. The search for scientific articles that made up this review was carried out on Google Scholar, Biological Abstract, HAL, Qeios, ResearchGate, Scielo, and SSRN. The following descriptors in Health Sciences (DeCS) were used: biological therapy, larva, wound, debridement, and healing. The following inclusion criteria were considered: Original articles and reviews, published nationally and internationally in full, available electronically, and published in Portuguese, English, and Spanish. The exclusion criteria were dissertations, theses, monographs, and conclusion work, duplicates, and those that required payment to access the content in full.
Electrolytes Status in Acute Stroke Patient in Rajshahi Medical College Hospital
Authors: Haque Md Azizul , Khan Mohammad Mahbubur Rahman , Kundu Pijush
Published: September 2024

Background: Stroke is a major cause of mortality and morbidity worldwide, significantly impacting patients and healthcare systems. Electrolyte imbalances are common in acute stroke patients and can influence clinical outcomes. This study investigates the electrolyte status in acute stroke patients admitted to Rajshahi Medical College Hospital Objective: To evaluate the electrolyte status (sodium and potassium levels) in acute stroke patients and its association with stroke types (Ischaemic and haemorrhagic) and clinical outcomes. Method: A cross-sectional study was conducted over two years (July 2017 to June 2019) in the Medicine and Neuromedicine Department of Rajshahi Medical College Hospital. A total of 104 acute stroke patients were included. Serum sodium and potassium levels were measured upon admission. Sociodemographic data, stroke types, and electrolyte levels were analyzed. Results: Among the 104 stroke patients, 71 (68.27%) had ischaemic stroke, and 33 (31.73%) had haemorrhagic stroke. The age distribution was highest in the 50-60 years group (34.62%). Males comprised 58.65% of the patients. Sodium levels were normal in 61.54% of patients, high in 2.88%, and low in 35.58%. Potassium levels were normal in 68.27% of patients, high in 10.58%, and low in 21.15%. No significant difference was found in sodium (p>0.05) and potassium (p>0.05) levels between ischaemic and haemorrhagic stroke patients. Conclusions: Electrolyte imbalances are prevalent in acute stroke patients, but no significant differences were observed between ischaemic and haemorrhagic stroke types. Regular monitoring and correction of electrolytes are crucial in managing stroke patients to improve outcomes.
Optimizing Neuroimaging Techniques for Enhanced Visualization of Intracranial Aneurysms
Authors: Farooq Ayesha Bintay , Hamza Muhammad Awais , Ijaz Izat , Ishaq Muhammad Umair , Yasin Alishba
Published: September 2024

Intracranial aneurysms, abnormal dilations of blood vessels in the brain, pose significant health risks, especially when ruptured, leading to conditions such as subarachnoid hemorrhage and stroke. The primary objective of this study is to evaluate the diagnostic accuracy of different computed tomography angiography (CTA) protocols for detecting intracranial aneurysms and to identify methods for optimizing scanning parameters to reduce radiation exposure while ensuring high image quality. Results from the analysis of various CTA protocols revealed that lowering tube voltages (80-120 kV) and milliampere seconds (mAs) effectively reduced radiation exposure without compromising the quality of images. Additionally, the use of advanced reconstruction algorithms, including deep learning techniques, significantly improved the visualization of small vascular structures, thereby enhancing diagnostic accuracy. These findings provide valuable insights for enhancing clinical practices in the fields of neurology and radiology.
The Pattern of Corneal Diseases in North Kordofan State
Authors: Ibraheim Khalil Ali
Published: September 2024

Background: All corneal diseases cause ocular morbidity and decrease vision, or even blindness, so early management intervention is critical. This study sought to evaluate several corneal disorders, including corneal foreign bodies, corneal tears, and ruptured globes. Methodology: This retrospective descriptive study was undertaken in El-Obeid Teaching Hospital's Ophthalmology Emergency Department in North Kordofan State, Sudan, as well as Dr. Khalil's Ophthalmology Center. This study sample, which represents the entire corneal illness, was obtained from 1000 patient files for various eye conditions. Results: This study examines 205 patients with corneal disorders to assess the prevalence of corneal diseases in North Kordofan State. The study found that the disease is more common in males, with 48 out of 78 patients (62%) being male and 38% being female. The male-to-female ratio is 1.6:1. The age group that is most affected is the group of individuals younger than 9 years, accounting for 34% of the affected population. This is followed by the age groups of 10–20 years, 21–32 years, 33–53 years, and >54 years, which account for 24%, 18%, 14%, and 9%, respectively. Regarding the classification of corneal disorders, the most prevalent form is foreign body corneal disease, accounting for 38% of cases. This is followed by corneal tear (16%), corneal opacity (15%), corneal tear with iris prolapses (10%), bacterial corneal ulcer (7%), and rupture globe (6%). The incidence rates of viral corneal ulcers, chemical trauma, burn trauma, and keratoconus are 3%, 3%, 1%, and 1%, respectively. Conclusion: Eye trauma is prevalent in north Kordofan, leading to an upsurge in corneal illnesses including foreign body cornea, corneal tear, and ruptured globe.
Amplitude Variations of Moving Distributed Masses of Orthotropic Rectangular Plate with Elastically Supported Ends under Moving Loads
Authors: S Adeoye A.
Published: September 2024

The deflection of thin orthotropic rectangular plate under moving loads is a classic problem in solid mechanics. However, the equations are challenging to solve due to their non linearity and complexity. At the same time, this equation is a coupled fourth order partial differential equation having variables and singular coefficients. In this research article, the partial differential equation is converted to a set of coupled second order ordinary differential equations by using a special technique adopted by Shadnam et al., [19]. This transformed set of second order ordinary differential equations is then reduced using modified asymptotic method of Struble and Laplce transformation. The closed form solution is evaluated, resonance conditions are obtained and the results are showed in plotted curves to solve the variations in amplitudes for some varying orthotropic plate parameters with elastically supported ends under moving loads for both cases of moving distributed force and moving distributed mass.
Flexural Rigidity Influence on Dynamic Response of Orthoropic Rectangular Plate Resting on Constant Elastic Foundation
Authors: S Adeoye, A. , O Adeloye, T.
Published: September 2024

This research article considers the flexural rigidity influence along both x and y axes on the dynamic response of orthotropic rectangular plate resting on constant elastic foundation with elastic end conditions. The orthotropic rectangular plate model is a coupled fourth order partial differential equation having variables and singular coefficients. The solutions to this model are arrived at by reconstructing the fourth order partial differential. This partial differential equation model is converted to a set of coupled second order ordinary differential equations by using a special technique adopted by Shadnam et al., [11]. This set of second order ordinary differential equations is then reduced using modified asymptotic method of Struble. The closed form solution is evaluated, resonance conditions are obtained and the results are showed in plotted curves to depict the influence of flexural rigidities along both x and y axes on the dynamic response of orthotropic rectangular plate resting on constant elastic foundation with elastic end conditions for both cases of moving distributed mass and moving distributed force.
Optimization of Flexural Strength of Sawdust Ash Blended Geopolymer Concrete
Authors: Gift Osere , Temple Nwofor , Samuel Dr. Sule
Published: September 2024

release of greenhouse gases linked to the manufacture of cement. Geopolymer as a binder for making concrete consists of two (2) main components; (1) the alkaline liquid consisting of sodium or potassium silicate and sodium or potassium hydroxide and (2) source material of geological origin or by-products rich in silica and alumina. The combination proportions utilised in this investigation were formulated utilising Scheffe's (5,2) basic lattice mix design approach with the intent to create the trial mix and the control mix. A total of thirty (30) geopolymers concrete sample mixes were made in the laboratory, with fifteen samples for trial mixes and fifteen mixtures for control mixes. These mixtures were used to appraise the performance of the sawdust ash geopolymer concrete in term of its flexural strength property. The study used sawdust ash as the source material and investigation revealed that subjecting sawdust ash to pyrolysis without oxygen has a notable impact on the pozzolanic characteristics of the constituent. Consequently, this also affects the flexural qualities of the concrete. Furthermore, it has been shown that softwood sawdust exhibits superior pozzolanic properties when compared to hardwood sawdust. The study revealed that the optimum flexural strength of sawdust ash blended geopolymer concrete is 3.3002 MPa and the corresponding mix deign obtained. Computer programs were created using Matlab and used for the optimization and prediction of the flexural strength of sawdust ash based geopolymer concrete.
Fungal Infections in Spondyloarthritis Patients Undergoing Biotherapy: Insights from the Moroccan Biotherapy Registry (RBSMR) over a Three-Year Follow-Up Period
Authors: Bourjila Salma , Rostom Samira , Souissi Abir , Binoune Imane EL , Amine Bouchra , Hmamouchi Ihsane , Abouqal, Redouane , Achemlal Lahcen , Allali Fadoua , Bouchti Imane El , Maghraoui Abdellah El , Ghozlani Imad El , Hassikou Hasna , Harzy Taoufik , Ichchou Linda , Mkinsi Ouafa , Niamane Radouane , Bahiri Rachid
Published: September 2024

Biological therapy increases the risk of fungal infections in chronic inflammatory rheumatism patients. Objectives: To determine the incidence of fungal infections in spondyloarthritis patients on biotherapy in the Moroccan registry (RBSMR) during 3-year follow-up and to identify associated factors. Methods: Patients' socio-demographic, clinical and para-clinical data were collected. The type of biotherapy used and episodes of fungal infections were determinated. Also, the frequency of corticosteroids and NSAIDs use, disease activity, and various comorbidities before and at the time of fungal infection during the 3 years of follow-up were defined. Regarding fungal infection, the germ and location were specified. Results: Seven spondyloarthritis patients out of 194 had a fungal infection (with 8 episodes). Mean age was 44±17 years, with mean disease duration of 11 years. All these patients had comorbidities before and during the fungal infection. At the time of this, all patients were on TNF alpha inhibitors, specifically, one patient was on Adalimumab but later switched to Etanercept, five were on Etanercept, and one was on Infliximab. No case of systemic fungal infection was noted. In the 8 fungal infection episodes, there were 7 cases of appendages’ involvement and 1 case of vaginal candidiasis. Conclusion: The incidence of fungal infections in patients with spondyloarthritis remains low and seems to be related to disease activity and type of biologics.
Updates in Management of Pulmonary Hypertension in Pediatrics: A Systematic Review
Authors: Nagadi Albatoul Yasser , Bafaqih Hind Ali , Qasem Abdullah Abdulrahim , Alkurdi Adnan Bakur , Alseheel Yaser Mohamed
Published: September 2024

Objectives: To provide an updated synthesis of the evidence on the management of pulmonary hypertension (PH) in pediatric patients. Methods: We performed a thorough search of electronic databases such as PubMed, Science Direct, Cochrane Library, and Scopus. Two independent reviewers evaluated and retrieved information from qualifying papers. Results: Our data consists of eight studies with 2003 children, 930 (46.3%) of whom were female. Prostacyclin agonists were found to significantly improve hemodynamic parameters and reduced BNP levels, which implies that they have promising clinical efficacy and a good tolerance profile. No major side effects were noted except for headaches and gastrointestinal symptoms. Systemic glucocorticoids, inhaled NO, endothelin receptor antagonists, and PDE showed tolerability and clinical improvements in pediatric PH. Side effects such as acute kidney damage, renal failure, and methemoglobinemia were noted with the inhaled NO. Conclusion: Pediatric PH is still a difficult condition with high morbidity and mortality. All of the reported pharmacological interventions demonstrated good clinical outcomes and almost no adverse effects. Healthcare practitioners can improve the care of children with PH and eventually improve their quality of life and long-term survival by incorporating new research into clinical practice.
Endodontic Non-Surgical Management of Dens Invaginatus Type Two with Open Apex and Separate Root Sheath: A Case Report and Literature Review
Authors: Alkhammash Nawaf , Hajji Mohammed Al , Fatani Bader Al
Published: September 2024

Dens invaginatus (DI) is a rare developmental anomaly with an unknown etiology and different complexity. It is classified into three types according to Oehler’s classification 1957 based on the extent of invagination. This case involves an upper lateral tooth demonstrating Dens invaginatus type 2, an open apex, and a separate root sheath and diagnosis of necrotic pulp with symptomatic apical periodontitis. A cone beam computed tomography (CBCT) assessment was conducted prior to nonsurgical root canal treatment, which included apexification with bio ceramic material and internal bleaching to address both healing potential and aesthetics. The procedure was performed under an operating microscope, and a 6-month follow-up was conducted with both clinical and radiographic signs of healing.
Hubungan Kesesuaian Kenaikan Berat Badan Ibu selama Hamil dengan Kejadian Ruptur Perineum di TPMB Farida Hajri Surabaya
Authors: Wuni Aulia Az Zahra , Ferdinandus Euvanggelia Dwilda , Prasetyo Budi
Published: September 2024

Ruptur perineum terjadi akibat adanya perlukaan pada jalan lahir baik menggunakan alat maupun tidak merupakan salah satu penyebab dari perdarahan postpartum, penyebab tidak langsung dari ruptur perineum adalah kenaikan berat badan yang berkaitan dengan berat bayi lahir. Hal ini menyebabkan meningkatnya angka kematian dan kesakitan pada ibu. Penelitian ini bertujuan untuk mengetahui hubungan kesesuaian kenaikan berat badan selama hamil dengan kejadian ruptur perineum, supaya tindak pencegahan sebagai salah satu pendukung SDG’s good health and well being pada maternal dapat ditingkatkan. Metode: Metode penelitian menggunakan analitik observasional dengan rancangan case control dan pendekatan secara retrospektif. Sampel dalam penelitian ini adalah 126 ibu postpartum pervaginam primipara yang melakukan persalinan normal di TPMB Farida Hajri Surabaya peiode Januari 2019–Desember 2022 yang termasuk ke dalam kriteria inklusi dan eksklusi dan ditentukan menggunakan teknik purposive sampling yang terdiri dari 63 kelompok kasus (ruptur perineum) dan 63 kelompok kontrol (tidak ruptur perineum). Instrumen yang digunakan berupa rekam medis. Data penelitian dianalisis menggunakan uji Chi-square (X2). Hasil: Hasil penelitian menunjukkan sebagian besar kelompok kasus yaitu 45 sampel (71,4%) mengalami kenaikan berat badan tidak sesuai dengan rekomendasi IOM, sedangkan sebagian besar kelompok kontrol yaitu 36 sampel (57,1%) mengalami kenaikan berat badan sesuai dengan rekomendasi IOM. Hasil uji didapatkan nilai p=0,001 (p<α), C=0,277, dan OR=3,333 (95% CI=1,590–6,987). Kesimpulan: Data tersebut menunjukkan bahwa terdapat hubungan signifikan antara kesesuaian kenaikan berat badan ibu selama hamil dengan kejadian ruptur perineum di TPMB Farida Hajri Surabaya.