bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 3 from Surveillance of the Tumor Mutanome by T Cells during Progression from Primary to Recurrent Ovarian Cancer
Authors: Wick Darin A. , Webb John R. , Nielsen Julie S. , Martin Spencer D. , Kroeger David R. , Milne Katy , Castellarin Mauro , Twumasi-Boateng Kwame , Watson Peter H. , Holt Rob A. , Nelson Brad H.
Published: April 2023

PDF file - 128K, Defining the minimal peptide containing the HSDL1L25V mutation recognized by Clone 1.
Supplementary Figure 1 from Surveillance of the Tumor Mutanome by T Cells during Progression from Primary to Recurrent Ovarian Cancer
Authors: Wick Darin A. , Webb John R. , Nielsen Julie S. , Martin Spencer D. , Kroeger David R. , Milne Katy , Castellarin Mauro , Twumasi-Boateng Kwame , Watson Peter H. , Holt Rob A. , Nelson Brad H.
Published: April 2023

PDF file - 133K, Lymphocyte infiltration and MHC expression in HGSC.
Supplementary Table 5 from Elevated TNFR1 and Serotonin in Bone Metastasis Are Correlated with Poor Survival following Bone Metastasis Diagnosis for Both Carcinoma and Sarcoma Primary Tumors
Authors: Chiechi Antonella , Novello Chiara , Magagnoli Giovanna , Petricoin Emanuel F. , Deng Jianghong , Benassi Maria S. , Picci Piero , Vaisman Iosif , Espina Virginia , Liotta Lance A.
Published: April 2023

XLSX file - 350K, Spearman's Rho correlation analysis results for the long-survivor group, using RPMA data.
Supplementary Table 4 from Elevated TNFR1 and Serotonin in Bone Metastasis Are Correlated with Poor Survival following Bone Metastasis Diagnosis for Both Carcinoma and Sarcoma Primary Tumors
Authors: Chiechi Antonella , Novello Chiara , Magagnoli Giovanna , Petricoin Emanuel F. , Deng Jianghong , Benassi Maria S. , Picci Piero , Vaisman Iosif , Espina Virginia , Liotta Lance A.
Published: April 2023

XLSX file - 242K, Spearman's Rho correlation analysis results for the entire study set, using RPMA data.
Supplementary Figure Legends from Interleukin-17A Modulates Circulating Tumor Cells in Tumor Draining Vein of Colorectal Cancers and Affects Metastases
Authors: Tseng Ju-Yu , Yang Chih-Yung , Liang Shu-Ching , Liu Ren-Shyan , Yang Shung-Haur , Lin Jen-Kou , Chen Yuh-Min , Wu Yu-Chung , Jiang Jeng-Kai , Lin Chi-Hung
Published: April 2023

PDF file - 104KB
Supplementary Table 2 from First-in-Human Phase I Trial of Two Schedules of OSI-930, a Novel Multikinase Inhibitor, Incorporating Translational Proof-of-Mechanism Studies
Authors: Yap Timothy A. , Arkenau Hendrik-Tobias , Camidge D. Ross , George Suzanne , Serkova Natalie J. , Gwyther Stephen J. , Spratlin Jennifer L. , Lal Rohit , Spicer James , Desouza Nandita M. , Leach Martin O. , Chick Jon , Poondru Srinivasu , Boinpally Ramesh , Gedrich Richard , Brock Katie , Stephens Andrew , Eckhardt S. Gail , Kaye Stan B. , Demetri George , Scurr Michelle
Published: April 2023

PDF file - 72K, The semi-quantitative DCE-MRI endpoints for assessment of tumor perfusion (IAUC) and overall tumor vascularity (AUC)
Supplementary Methods, Figure Legend from Preclinical Activity Profile and Therapeutic Efficacy of the HSP90 Inhibitor Ganetespib in Triple-Negative Breast Cancer
Authors: Proia David A. , Zhang Chaohua , Sequeira Manuel , Jimenez John-Paul , He Suqin , Spector Neil , Shapiro Geoffrey I. , Tolaney Sara , Nagai Masazumi , Acquaviva Jaime , Smith Donald L. , Sang Jim , Bates Richard C. , El-Hariry Iman
Published: April 2023

PDF file - 62K
Supplementary Figure 4 from Contribution of Abcc4-Mediated Gastric Transport to the Absorption and Efficacy of Dasatinib
Authors: Furmanski Brian D. , Hu Shuiying , Fujita Ken-ichi , Li Lie , Gibson Alice A. , Janke Laura J. , Williams Richard T. , Schuetz John D. , Sparreboom Alex , Baker Sharyn D.
Published: April 2023

PDF file - 88K, Expression of Abcb1 and Abcg2 in mouse intestine.
Supplementary Figure 3 from Contribution of Abcc4-Mediated Gastric Transport to the Absorption and Efficacy of Dasatinib
Authors: Furmanski Brian D. , Hu Shuiying , Fujita Ken-ichi , Li Lie , Gibson Alice A. , Janke Laura J. , Williams Richard T. , Schuetz John D. , Sparreboom Alex , Baker Sharyn D.
Published: April 2023

PDF file - 399K, Influence of Abcc4 function on dasatinib disposition.
Supplementary Figure 2 from Phase I Dendritic Cell p53 Peptide Vaccine for Head and Neck Cancer
Authors: Schuler Patrick J. , Harasymczuk Malgorzata , Visus Carmen , DeLeo Albert , Trivedi Sumita , Lei Yu , Argiris Athanassios , Gooding William , Butterfield Lisa H. , Whiteside Theresa L. , Ferris Robert L.
Published: April 2023

PDF file - 120KB, Representative examples of flow cytometric gating and quantification of CD4, CD25, CD39, and FOXP3 on Treg subsets.
Supplementary Fig. S2 from Phase I Safety, Pharmacokinetic and Pharmacodynamic Evaluation of the Vascular Disrupting Agent Ombrabulin (AVE8062) in Patients with Advanced Solid Tumors
Authors: Sessa Cristiana , Lorusso Patricia , Tolcher Anthony , Farace Françoise , Lassau Nathalie , Delmonte Angelo , Braghetti Antonio , Bahleda Rastislav , Cohen Patrick , Hospitel Marie , Veyrat-Follet Christine , Soria Jean-Charles
Published: April 2023

Supplementary Fig. S2 - PDF file 123K, Change in Fridericia-corrected QT interval from baseline vs ombrabulin (A) and RPR258063 (B) concentrations as the predictor
Supplementary Figure 9 from Caspase-Independent Cell Death Is Involved in the Negative Effect of EGF Receptor Inhibitors on Cisplatin in Non–Small Cell Lung Cancer Cells
Authors: Yamaguchi Hirohito , Hsu Jennifer L. , Chen Chun-Te , Wang Ying-Nai , Hsu Ming-Chuan , Chang Shih-Shin , Du Yi , Ko How-Wen , Herbst Roy , Hung Mien-Chie
Published: April 2023

PDF file - 87K, The effects of cisplatin and/or gefitinb on FOXO3a phosphorylation and Mn-SOD expression in H1299-Blc-XL xenograft tumors
Supplementary Figure 8 from Caspase-Independent Cell Death Is Involved in the Negative Effect of EGF Receptor Inhibitors on Cisplatin in Non–Small Cell Lung Cancer Cells
Authors: Yamaguchi Hirohito , Hsu Jennifer L. , Chen Chun-Te , Wang Ying-Nai , Hsu Ming-Chuan , Chang Shih-Shin , Du Yi , Ko How-Wen , Herbst Roy , Hung Mien-Chie
Published: April 2023

PDF file - 154K, The role of Mn-SOD or catalase on cisplatin-induced CID
Supplementary Tables 1 - 4, Figures 1 - 4 from MicroRNA-202-3p Inhibits Cell Proliferation by Targeting ADP-Ribosylation Factor-like 5A in Human Colorectal Carcinoma
Authors: Wang Qifeng , Huang Zhaohui , Guo Weijie , Ni Shujuan , Xiao Xiuying , Wang Lisha , Huang Dan , Tan Cong , Xu Qinghua , Zha Ruopeng , Zhang Jiwei , Sheng Weiqi , He Xianghuo , Du Xiang
Published: April 2023

PDF file - 543K, Table S1. Patient information. Table S2. Primers sequences. Table S3. siRNA sequences for potential target genes Table S4. Downregulated genes in miR-202-3p-transfected LoVo cells. Fig S1: The influence of miR-202-3p T:N expression ratios levels on the overall survival of CRC patients. Fig S2: The effect of miR-202-3p on tumor formation in a nude mouse xenograft model. Fig S3: The expression levels of ARL5A mRNA in HCT-116 and LoVo cells infected with miR-202-3p or control lentiviruses were determined by qRT-PCR. Beta-actin mRNA served as an internal control. Fig S4: Immunohistochemical staining of ARL5A in the CRC and NCT samples is shown.
Supplementary Figure 4 from Regulation of Cell Proliferation and Migration by Keratin19-Induced Nuclear Import of Early Growth Response-1 in Breast Cancer Cells
Authors: Ju Ji-hyun , Yang Wonseok , Lee Kyung-min , Oh Sunhwa , Nam KeeSoo , Shim Sarah , Shin Soon Young , Gye Myung Chan , Chu In-Sun , Shin Incheol
Published: April 2023

Supplementary Figure 4 - PDF file 1098K, KRT19 inhibition does not down-regulate PTEN protein level through modulation of PTEN stability
Supplementary Fig. 7A from Regulation of Cell Proliferation and Migration by Keratin19-Induced Nuclear Import of Early Growth Response-1 in Breast Cancer Cells
Authors: Ju Ji-hyun , Yang Wonseok , Lee Kyung-min , Oh Sunhwa , Nam KeeSoo , Shim Sarah , Shin Soon Young , Gye Myung Chan , Chu In-Sun , Shin Incheol
Published: April 2023

Supplementary Fig. 7A - PDF file 188K, Correlation between KRT19 and HER2 expression in breast cancer patient samples
Supplementary Table 3 from Identification of a Subset of Human Non–Small Cell Lung Cancer Patients with High PI3Kβ and Low PTEN Expression, More Prevalent in Squamous Cell Carcinoma
Authors: Cumberbatch Marie , Tang Ximing , Beran Garry , Eckersley Sonia , Wang Xin , Ellston Rebecca P.A. , Dearden Simon , Cosulich Sabina , Smith Paul D. , Behrens Carmen , Kim Edward S. , Su Xinying , Fan Shuqiong , Gray Neil , Blowers David P. , Wistuba Ignacio I. , Womack Chris
Published: April 2023

PDF file - 78K, Mutation status of AZ samples acquired through Liverpool Heart and Chest Hospital.
Supplementary Tables 1 - 2 from Antagonism of SET Using OP449 Enhances the Efficacy of Tyrosine Kinase Inhibitors and Overcomes Drug Resistance in Myeloid Leukemia
Authors: Agarwal Anupriya , MacKenzie Ryan J. , Pippa Raffaella , Eide Christopher A. , Oddo Jessica , Tyner Jeffrey W. , Sears Rosalie , Vitek Michael P. , Odero María D. , Christensen Dale J. , Druker Brian J.
Published: April 2023

PDF file - 73KB, CML (Table 1) and AML (Table 2) Patient sample information.
Supplementary Data from Merkel Polyomavirus-Specific T Cells Fluctuate with Merkel Cell Carcinoma Burden and Express Therapeutically Targetable PD-1 and Tim-3 Exhaustion Markers
Authors: Afanasiev Olga K. , Yelistratova Lola , Miller Natalie , Nagase Kotaro , Paulson Kelly , Iyer Jayasri G. , Ibrani Dafina , Koelle David M. , Nghiem Paul
Published: April 2023

Supplementary Data - PDF file 227K, Supplementaty Data Figure S1. Representative flow cytometry gating scheme for TIL and PBMC surface marker analysis. Figure S2. Representative data showing IFN-y production in response to no stimulation (top row) or to PMA/ionomycin stimulation (bottom row)
Supplementary Table 2 from Development and Characterization of HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinoma Tumorgrafts
Authors: Kimple Randall J. , Harari Paul M. , Torres Alexandra D. , Yang Robert Z. , Soriano Benjamin J. , Yu Menggang , Armstrong Eric A. , Blitzer Grace C. , Smith Molly A. , Lorenz Laurel D. , Lee Denis , Yang David T. , McCulloch Timothy M. , Hartig Gregory K. , Lambert Paul F.
Published: April 2023

XLSX file - 76K, Differentiation of tumorgraft passages
Supplementary Table 2 from Characteristics and Clinical Impacts of the Immune Environments in Colorectal and Renal Cell Carcinoma Lung Metastases: Influence of Tumor Origin
Authors: Remark Romain , Alifano Marco , Cremer Isabelle , Lupo Audrey , Dieu-Nosjean Marie-Caroline , Riquet Marc , Crozet Lucile , Ouakrim Hanane , Goc Jeremy , Cazes Aurélie , Fléjou Jean-François , Gibault Laure , Verkarre Virginie , Régnard Jean-François , Pagès Olivier-Nicolas , Oudard Stéphane , Mlecnik Bernhard , Sautès-Fridman Catherine , Fridman Wolf-Herman , Damotte Diane
Published: April 2023

PDF file - 83K, Baseline characteristics of 52 patients with RCC lung metastasis. * determined by Heng et al.
Supplementary Figure 5 from Overexpression of Sirt7 Exhibits Oncogenic Property and Serves as a Prognostic Factor in Colorectal Cancer
Authors: Yu Hongyan , Ye Wen , Wu Jiangxue , Meng Xiangqi , Liu Ran-yi , Ying Xiaofang , Zhou Yi , Wang Hui , Pan Changchuan , Huang Wenlin
Published: April 2023

PDF file - 2515KB, Sirt7 induces CRC cell migration in vitro partly dependent on the ERK activated. PD98059 can inhibit the migration of THC8307 that overexpressed Sirt7 while the inhibited effect was not depentent on the dose of PD98059.
Supplementary Methods and Figure Legend from ZEB1 Promotes Invasiveness of Colorectal Carcinoma Cells through the Opposing Regulation of uPA and PAI-1
Authors: Sánchez-Tilló Ester , de Barrios Oriol , Siles Laura , Amendola Pier G. , Darling Douglas S. , Cuatrecasas Miriam , Castells Antoni , Postigo Antonio
Published: April 2023

PDF file - 195K
Supplementary Table 1 from Chemoprevention of Head and Neck Cancer by Simultaneous Blocking of Epidermal Growth Factor Receptor and Cyclooxygenase-2 Signaling Pathways: Preclinical and Clinical Studies
Authors: Shin Dong M. , Zhang Hongzheng , Saba Nabil F. , Chen Amy Y. , Nannapaneni Sreenivas , Amin A.R.M. Ruhul , Müller Susan , Lewis Melinda , Sica Gabriel , Kono Scott , Brandes Johann C. , Grist William J. , Moreno-Williams Rachel , Beitler Jonathan J. , Thomas Sufi M. , Chen Zhengjia , Shin Hyung Ju C. , Grandis Jennifer R. , Khuri Fadlo R. , Chen Zhuo Georgia
Published: April 2023

Summary of the top 27 genes/proteins associated with clinical response
Supplementary Table S2 from Contrasting Expression Patterns of Histone mRNA and microRNA 760 in Patients with Gastric Cancer
Authors: Iwaya Takeshi , Fukagawa Takeo , Suzuki Yutaka , Takahashi Yusuke , Sawada Genta , Ishibashi Masahisa , Kurashige Junji , Sudo Tomoya , Tanaka Fumiaki , Shibata Kohei , Endo Fumitaka , Katagiri Hirokatsu , Ishida Kaoru , Kume Kohei , Nishizuka Satoshi , Iinuma Hisae , Wakabayashi Go , Mori Masaki , Sasako Mitsuru , Mimori Koshi
Published: April 2023

XLS file 15K, HIST1H3D expression and clinicopathological factors
Supplementary Figure 3 from In Vivo Fluorescence Lifetime Imaging for Monitoring the Efficacy of the Cancer Treatment
Authors: Ardeshirpour Yasaman , Chernomordik Victor , Hassan Moinuddin , Zielinski Rafal , Capala Jacek , Gandjbakhche Amir
Published: April 2023

PDF file - 232KB, Average fluorescence intensity at the tumor and contralateral site (for one mouse) 12 hours after the last treatment.
Supplementary Table 2 from HIF-1α of Bone Marrow Endothelial Cells Implies Relapse and Drug Resistance in Patients with Multiple Myeloma and May Act as a Therapeutic Target
Authors: Ria Roberto , Catacchio Ivana , Berardi Simona , De Luisi Annunziata , Caivano Antonella , Piccoli Claudia , Ruggieri Vitalba , Frassanito Maria Antonia , Ribatti Domenico , Nico Beatrice , Annese Tiziana , Ruggieri Simona , Guarini Attilio , Minoia Carla , Ditonno Paolo , Angelucci Emanuele , Derudas Daniele , Moschetta Michele , Dammacco Franco , Vacca Angelo
Published: April 2023

PDF file - 23K, Proteins identified in MMECs upon HIF-1�siRNA and panobinostat treatment (MALDITOFF mass spectrometry).
Supplementary Figure 4 from HIF-1α of Bone Marrow Endothelial Cells Implies Relapse and Drug Resistance in Patients with Multiple Myeloma and May Act as a Therapeutic Target
Authors: Ria Roberto , Catacchio Ivana , Berardi Simona , De Luisi Annunziata , Caivano Antonella , Piccoli Claudia , Ruggieri Vitalba , Frassanito Maria Antonia , Ribatti Domenico , Nico Beatrice , Annese Tiziana , Ruggieri Simona , Guarini Attilio , Minoia Carla , Ditonno Paolo , Angelucci Emanuele , Derudas Daniele , Moschetta Michele , Dammacco Franco , Vacca Angelo
Published: April 2023

PDF file - 2376K, Panobinostat effect on MMECs in the presence of BM cells and proteomic analysis of MMECs upon treatment with HIF-1α·siRNA or panobinostat.
Supplementary Methods from Promoter CpG Island Methylation of Genes in Key Cancer Pathways Associates with Clinical Outcome in High-Grade Serous Ovarian Cancer
Authors: Dai Wei , Zeller Constanze , Masrour Nahal , Siddiqui Nadeem , Paul James , Brown Robert
Published: April 2023

PDF file - 100K
Supplementary Figure Legend from Promoter CpG Island Methylation of Genes in Key Cancer Pathways Associates with Clinical Outcome in High-Grade Serous Ovarian Cancer
Authors: Dai Wei , Zeller Constanze , Masrour Nahal , Siddiqui Nadeem , Paul James , Brown Robert
Published: April 2023

Supplementary Figure Legend - PDF file 6K, Supplementary Figure 1 legend
Supplementary Figure 1 from HIF-1α of Bone Marrow Endothelial Cells Implies Relapse and Drug Resistance in Patients with Multiple Myeloma and May Act as a Therapeutic Target
Authors: Ria Roberto , Catacchio Ivana , Berardi Simona , De Luisi Annunziata , Caivano Antonella , Piccoli Claudia , Ruggieri Vitalba , Frassanito Maria Antonia , Ribatti Domenico , Nico Beatrice , Annese Tiziana , Ruggieri Simona , Guarini Attilio , Minoia Carla , Ditonno Paolo , Angelucci Emanuele , Derudas Daniele , Moschetta Michele , Dammacco Franco , Vacca Angelo
Published: April 2023

PDF file - 114K, Lack of HIF-1alpha expression by BM macrophages in normoxia condition.
Supplementary Table 1, Figures 1 - 5 from Targeted Delivery of microRNA-29b by Transferrin-Conjugated Anionic Lipopolyplex Nanoparticles: A Novel Therapeutic Strategy in Acute Myeloid Leukemia
Authors: Huang Xiaomeng , Schwind Sebastian , Yu Bo , Santhanam Ramasamy , Wang Hongyan , Hoellerbauer Pia , Mims Alice , Klisovic Rebecca , Walker Alison R. , Chan Kenneth K. , Blum William , Perrotti Danilo , Byrd John C. , Bloomfield Clara D. , Caligiuri Michael A. , Lee Robert J. , Garzon Ramiro , Muthusamy Natarajan , Lee Ly James , Marcucci Guido
Published: April 2023

PDF file - 325K, Supplemental Table 1: Particle Size Distribution and Zeta Potential; Supplemental Figure 1: Transferrin receptor (CD71) expression on AML patient blasts; Supplemental Figure 2: miR entrapment efficiency; Supplemental Figure 3: Relative expression of miR-29b in AML cell lines, patient blasts and bone marrow samples from healthy donors; Supplemental Figure 4: Expression of pri-miR-29b-1 and pri-miR-29b-2 in AML cell lines and patient blasts following Tf-NP-miR-29b treatment; Supplemental Figure 5: Safety profile of Tf-NPs treatment in immune competent mice.
Supplementary Methods from Altered Microenvironment Promotes Progression of Preinvasive Breast Cancer: Myoepithelial Expression of αvβ6 Integrin in DCIS Identifies High-risk Patients and Predicts Recurrence
Authors: Allen Michael D. , Thomas Gareth J. , Clark Sarah , Dawoud Marwa M. , Vallath Sabarinath , Payne Sarah J. , Gomm Jennifer J. , Dreger Sally A. , Dickinson Sarah , Edwards Dylan R. , Pennington Caroline J. , Sestak Ivana , Cuzick Jack , Marshall John F. , Hart Ian R. , Jones J. Louise
Published: April 2023

PDF file - 91K
Supplementary Figure 1 from Reciprocal Interactions between Tumor-Associated Macrophages and CD44-Positive Cancer Cells via Osteopontin/CD44 Promote Tumorigenicity in Colorectal Cancer
Authors: Rao Guanhua , Wang Hongyi , Li Baowei , Huang Li , Xue Danfeng , Wang Xiaohui , Jin Haijing , Wang Jun , Zhu Yushan , Lu Youyong , Du Lei , Chen Quan
Published: April 2023

PDF file - 1330K, TAMs promote tumorigenicity of colorectal cancer cells.
Supplementary Figure 2 from Cabozantinib Inhibits Prostate Cancer Growth and Prevents Tumor-Induced Bone Lesions
Authors: Dai Jinlu , Zhang Honglai , Karatsinides Andreas , Keller Jill M. , Kozloff Kenneth M. , Aftab Dana T. , Schimmoller Frauke , Keller Evan T.
Published: April 2023

PDF file 95K, Cabozantinib does not inhibit progression of PC-3luc PCa cells in bone in vivo
Supplementary Methods from Antitumoral Activity of Lenalidomide in In Vitro and In Vivo Models of Mantle Cell Lymphoma Involves the Destabilization of Cyclin D1/p27KIP1 Complexes
Authors: Moros Alexandra , Bustany Sophie , Cahu Julie , Saborit-Villarroya Ifigènia , Martínez Antonio , Colomer Dolors , Sola Brigitte , Roué Gaël
Published: April 2023

PDF file - 78K
Supplementary Figure 1 from Cabozantinib Inhibits Prostate Cancer Growth and Prevents Tumor-Induced Bone Lesions
Authors: Dai Jinlu , Zhang Honglai , Karatsinides Andreas , Keller Jill M. , Kozloff Kenneth M. , Aftab Dana T. , Schimmoller Frauke , Keller Evan T.
Published: April 2023

PDF file 97K, Cabozantinib inhibits the progression of C4-2B PCa cells in bone in vivo
Supplementary Figure Legend from DNA Methyltransferase Inhibition Reverses Epigenetically Embedded Phenotypes in Lung Cancer Preferentially Affecting Polycomb Target Genes
Authors: Hascher Antje , Haase Ann-Kristin , Hebestreit Katja , Rohde Christian , Klein Hans-Ulrich , Rius Maria , Jungen Dominik , Witten Anika , Stoll Monika , Schulze Isabell , Ogawa Seishi , Wiewrodt Rainer , Tickenbrock Lara , Berdel Wolfgang E. , Dugas Martin , Thoennissen Nils H. , Müller-Tidow Carsten
Published: April 2023

PDF file - 52K
Supplementary Table 6 - 10 from Proteome Profiling of Cancer-Associated Fibroblasts Identifies Novel Proinflammatory Signatures and Prognostic Markers for Colorectal Cancer
Authors: Torres Sofia , Bartolomé Rubén A. , Mendes Marta , Barderas Rodrigo , Fernandez-Aceñero M. Jesús , Peláez-García Alberto , Peña Cristina , Lopez-Lucendo María , Villar-Vázquez Roi , de Herreros Antonio García , Bonilla Felix , Casal J. Ignacio
Published: April 2023

PDF file - 69K, S6, S7 Gene Ontology analysis of whole cellular extract (S6) or conditioned media (S7) proteins from CAFs versus NFs S8, S9 Ingenuity Pathway Analysis (S8) or FatiGo Analysis (S9) of the most important biological functions and pathways altered S10 Clinical data of patients in according to stromal expression of CAF markers
Supplementary Table 3 from Proteome Profiling of Cancer-Associated Fibroblasts Identifies Novel Proinflammatory Signatures and Prognostic Markers for Colorectal Cancer
Authors: Torres Sofia , Bartolomé Rubén A. , Mendes Marta , Barderas Rodrigo , Fernandez-Aceñero M. Jesús , Peláez-García Alberto , Peña Cristina , Lopez-Lucendo María , Villar-Vázquez Roi , de Herreros Antonio García , Bonilla Felix , Casal J. Ignacio
Published: April 2023

XLSX file - 312K, Global list of proteins identified and quantified in the conditioned medium of CAFs
Supplementary Table 2 from Proteome Profiling of Cancer-Associated Fibroblasts Identifies Novel Proinflammatory Signatures and Prognostic Markers for Colorectal Cancer
Authors: Torres Sofia , Bartolomé Rubén A. , Mendes Marta , Barderas Rodrigo , Fernandez-Aceñero M. Jesús , Peláez-García Alberto , Peña Cristina , Lopez-Lucendo María , Villar-Vázquez Roi , de Herreros Antonio García , Bonilla Felix , Casal J. Ignacio
Published: April 2023

XLSX file - 1349K, Global list of proteins identified and differentially-expressed in whole cellular extracts of CAFs
Supplementary Methods from Proteome Profiling of Cancer-Associated Fibroblasts Identifies Novel Proinflammatory Signatures and Prognostic Markers for Colorectal Cancer
Authors: Torres Sofia , Bartolomé Rubén A. , Mendes Marta , Barderas Rodrigo , Fernandez-Aceñero M. Jesús , Peláez-García Alberto , Peña Cristina , Lopez-Lucendo María , Villar-Vázquez Roi , de Herreros Antonio García , Bonilla Felix , Casal J. Ignacio
Published: April 2023

PDF file - 88K
Supplementary Table 1 from A Phase I Study of Quisinostat (JNJ-26481585), an Oral Hydroxamate Histone Deacetylase Inhibitor with Evidence of Target Modulation and Antitumor Activity, in Patients with Advanced Solid Tumors
Authors: Venugopal Balaji , Baird Richard , Kristeleit Rebecca S. , Plummer Ruth , Cowan Richard , Stewart Adam , Fourneau Nele , Hellemans Peter , Elsayed Yusri , Mcclue Steve , Smit Johan W. , Forslund Ann , Phelps Charles , Camm John , Evans T.R. Jeffry , de Bono Johann S. , Banerji Udai
Published: April 2023

Supplementary Table 1 - PDF file 54K, Number (percentage) of patients exhibiting increased ventricular ectopic activity
Supplementary Appendix from Sorafenib in Combination with Oxaliplatin, Leucovorin, and Fluorouracil (Modified FOLFOX6) as First-line Treatment of Metastatic Colorectal Cancer: The RESPECT Trial
Authors: Tabernero Josep , Garcia-Carbonero Rocio , Cassidy James , Sobrero Alberto , Van Cutsem Eric , Köhne Claus-Henning , Tejpar Sabine , Gladkov Oleg , Davidenko Irina , Salazar Ramon , Vladimirova Liubov , Cheporov Sergey , Burdaeva Olga , Rivera Fernando , Samuel Leslie , Bulavina Irina , Potter Vanessa , Chang Yu-Lin , Lokker Nathalie A. , O'Dwyer Peter J.
Published: April 2023

Supplementary Appendix
Supplementary Table 1 from Glioma Grade Is Associated with the Accumulation and Activity of Cells Bearing M2 Monocyte Markers
Authors: Prosniak Michael , Harshyne Larry A. , Andrews David W. , Kenyon Lawrence C. , Bedelbaeva Kamila , Apanasovich Tatiyana V. , Heber-Katz Ellen , Curtis Mark T. , Cotzia Paolo , Hooper D. Craig
Published: April 2023

PDF - 45K, Summary of clinical characteristics from archived tissues analyzed
Supplementary Figure 2 from Combination Immunotherapy after ASCT for Multiple Myeloma Using MAGE-A3/Poly-ICLC Immunizations Followed by Adoptive Transfer of Vaccine-Primed and Costimulated Autologous T Cells
Authors: Rapoport Aaron P. , Aqui Nicole A. , Stadtmauer Edward A. , Vogl Dan T. , Xu Yin Yan , Kalos Michael , Cai Ling , Fang Hong-Bin , Weiss Brendan M. , Badros Ashraf , Yanovich Saul , Akpek Gorgun , Tsao Patricia , Cross Alan , Mann Dean , Philip Sunita , Kerr Naseem , Brennan Andrea , Zheng Zhaohui , Ruehle Kathleen , Milliron Todd , Strome Scott E. , Salazar Andres M. , Levine Bruce L. , June Carl H.
Published: April 2023

PDF file - 1065KB, Supplemental Data for Figure 4.
Supplementary Figure 3 from Targeting PI3K/mTOR Overcomes Resistance to HER2-Targeted Therapy Independent of Feedback Activation of AKT
Authors: O'Brien Neil A. , McDonald Karen , Tong Luo , von Euw Erika , Kalous Ondrej , Conklin Dylan , Hurvitz Sara A. , di Tomaso Emmanuelle , Schnell Christian , Linnartz Ronald , Finn Richard S. , Hirawat Samit , Slamon Dennis J.
Published: April 2023

PDF file - 36K, Figure S3. Xenograft response data for 7-day tissue acquisition studies. A-C, SUM190, UACC812 and KPL-1 xenografts (6 mice per arm) were treated with BKM120 at 35 mg/kg, BYL719 at 50 mg/kg, RAD001 at 10 mg/kg and BEZ235 at 30 mg/kg, all daily PO. Trastuzumab was given at given at 10 mg/kg IP twice weekly. For SUM190 (A), tumors were collected 2.5 hours post final dose, for UACC812 (B) and KPL-1 (C), samples were collected 24 hours post final dose.
Supplementary Figure 1 from Targeting PI3K/mTOR Overcomes Resistance to HER2-Targeted Therapy Independent of Feedback Activation of AKT
Authors: O'Brien Neil A. , McDonald Karen , Tong Luo , von Euw Erika , Kalous Ondrej , Conklin Dylan , Hurvitz Sara A. , di Tomaso Emmanuelle , Schnell Christian , Linnartz Ronald , Finn Richard S. , Hirawat Samit , Slamon Dennis J.
Published: April 2023

PDF file - 772K, Figure S1: Targeting the PI3K/mTOR pathway in HER2-amplified breast cancer cell lines. Effect of A, RAD001, B, BEZ235, C, BKM120 or D, BYL719 treatment on PI3K/mTOR signaling in two representative cell lines; SKBR3 and MDA453 (PIK3CA mutant H1047R). All lysates taken 24 hours post-treatment.
Supplementary Tables 1-13 from Integrative Genomics Analysis Identifies Candidate Drivers at 3q26-29 Amplicon in Squamous Cell Carcinoma of the Lung
Authors: Wang Jing , Qian Jun , Hoeksema Megan D. , Zou Yong , Espinosa Allan V. , Rahman S.M. Jamshedur , Zhang Bing , Massion Pierre P.
Published: April 2023

Supplementary Tables 1-13 - PDF file 135K, Supplementary Table S1: Amplification scores and average expression scores for all paired samples based on the TCGA copy number data and gene expression data Table S2: The corr_exp_amp and corr_exp_ave for 164 genes in the 3q26-39 regions Table S3 Description of six datasets using to identify candidate driver genes Table S4 Predicted information based on GSE2109 Table S5 Predicted information based on GSE3141 Table S6 Predicted information based on GSE4573 Table S7 Predicted information based on GSE8894 Table S8 Predicted information based on GSE17710 Table S9 Predicted information based on Roepman et al. dataset Table S10 Order statistic result for 181 genes in 3q26�29 Table S11 Correlation between gene expression and 3q26-29 amplification level for identified 20 genes in head and neck SCC Table S12 Correlation between gene expression and 3q26-29 amplification level for identified 20 genes in cervical SCC Table S13 Copy number alteration and mRNA expression of four genes in a panel of NSCLC cell lines (data from Cancer Cell Line Encyclopedia database)
Supplementary Figure 1 from A Phase I/II, Multiple-Dose, Dose-Escalation Study of Siltuximab, an Anti-Interleukin-6 Monoclonal Antibody, in Patients with Advanced Solid Tumors
Authors: Angevin Eric , Tabernero Josep , Elez Elena , Cohen Steven J. , Bahleda Rastilav , van Laethem Jean-Luc , Ottensmeier Christian , Lopez-Martin Jose A. , Clive Sally , Joly Florence , Ray-Coquard Isabelle , Dirix Luc , Machiels Jean-Pascal , Steven Neil , Reddy Manjula , Hall Brett , Puchalski Thomas A. , Bandekar Rajesh , van de Velde Helgi , Tromp Brenda , Vermeulen Jessica , Kurzrock Razelle
Published: April 2023

PDF file - 25KB, Supplementary Figure S1. Patient disposition: AE, adverse event. KRAS, Kirsten rat sarcoma-2. PD, progressive disease. q2w, every 2 weeks. q3w, every 3 weeks.
Supplementary Materials from Therapeutic Potential of HSP90 Inhibition for Neurofibromatosis Type 2
Authors: Tanaka Karo , Eskin Ascia , Chareyre Fabrice , Jessen Walter J. , Manent Jan , Niwa-Kawakita Michiko , Chen Ruihong , White Cory H. , Vitte Jeremie , Jaffer Zahara M. , Nelson Stanley F. , Rubenstein Allan E. , Giovannini Marco
Published: April 2023

Supplementary Materials - PDF files 113K, Materials and Methods
Supplementary Figure Legends from Therapeutic Potential of HSP90 Inhibition for Neurofibromatosis Type 2
Authors: Tanaka Karo , Eskin Ascia , Chareyre Fabrice , Jessen Walter J. , Manent Jan , Niwa-Kawakita Michiko , Chen Ruihong , White Cory H. , Vitte Jeremie , Jaffer Zahara M. , Nelson Stanley F. , Rubenstein Allan E. , Giovannini Marco
Published: April 2023

Supplementary Figure Legends - PDF files 65K, Figure Legends
Supplementary Table 2 from PI3K Pathway Activation in High-Grade Ductal Carcinoma In Situ—Implications for Progression to Invasive Breast Carcinoma
Authors: Sakr Rita A. , Weigelt Britta , Chandarlapaty Sarat , Andrade Victor P. , Guerini-Rocco Elena , Giri Dilip , Ng Charlotte K.Y. , Cowell Catherine F. , Rosen Neal , Reis-Filho Jorge S. , King Tari A.
Published: April 2023

PDF file - 39KB, PI3K pathway alterations in pure high-grade DCIS, high-grade DCIS components adjacent to IBC, and in synchronous IBC components.
Supplementary Figure S5 from Targeting Small Cell Lung Cancer Harboring PIK3CA Mutation with a Selective Oral PI3K Inhibitor PF-4989216
Authors: Walls Marlena , Baxi Sangita M. , Mehta Pramod P. , Liu Kevin K.-C. , Zhu JinJiang , Estrella Heather , Li Chunze , Zientek Michael , Zong Qing , Smeal Tod , Yin Min-Jean
Published: April 2023

PDF file 58K, Supplementary Figure S5: Basal AKT phosphorylation is higher in SCLC lines with either PIK3CA mutation or PTEN loss
Supplementary Figure S2 from Targeting Small Cell Lung Cancer Harboring PIK3CA Mutation with a Selective Oral PI3K Inhibitor PF-4989216
Authors: Walls Marlena , Baxi Sangita M. , Mehta Pramod P. , Liu Kevin K.-C. , Zhu JinJiang , Estrella Heather , Li Chunze , Zientek Michael , Zong Qing , Smeal Tod , Yin Min-Jean
Published: April 2023

PDF file 78K, Supplementary Figure S2: Introduction of PTEN enhanced PF-4989216 inhibition in Lu134B cells but not in Lu134A
Supplementary Methods from Tumor Genetic Analyses of Patients with Metastatic Melanoma Treated with the BRAF Inhibitor Dabrafenib (GSK2118436)
Authors: Nathanson Katherine L. , Martin Anne-Marie , Wubbenhorst Bradley , Greshock Joel , Letrero Richard , D'Andrea Kurt , O'Day Steven , Infante Jeffrey R. , Falchook Gerald S. , Arkenau Hendrik-Tobias , Millward Michael , Brown Michael P. , Pavlick Anna , Davies Michael A. , Ma Bo , Gagnon Robert , Curtis Martin , Lebowitz Peter F. , Kefford Richard , Long Georgina V.
Published: April 2023

Supplementary Methods - PDF file 95K, Supplementary Methods
Supplementary Figure 6 from Stearoyl-CoA Desaturase 1 Is a Novel Molecular Therapeutic Target for Clear Cell Renal Cell Carcinoma
Authors: von Roemeling Christina A. , Marlow Laura A. , Wei Johnny J. , Cooper Simon J. , Caulfield Thomas R. , Wu Kevin , Tan Winston W. , Tun Han W. , Copland John A.
Published: April 2023

Supplementary Figure 6: temsirolimus and SCD1 inhibitor synergy in vitro - PDF file 5856K, Treatment of ccRCC cells with SCD1 inhibitor in combination with the mTOR inhibitor temsirolimus synergistically inhibits tumor cell growth in vitro
Supplementary Figure 2 from Stearoyl-CoA Desaturase 1 Is a Novel Molecular Therapeutic Target for Clear Cell Renal Cell Carcinoma
Authors: von Roemeling Christina A. , Marlow Laura A. , Wei Johnny J. , Cooper Simon J. , Caulfield Thomas R. , Wu Kevin , Tan Winston W. , Tun Han W. , Copland John A.
Published: April 2023

Supplementary Figure 2: Inhibition of SCD1 induces ER stress - PDF file 1316K, Inhibition of SCD1 activity in ccRCC induces endoplasmic reticulum stress response in ccRCC
Supplementary Figure 2 from T Lymphocytes Redirected against the Chondroitin Sulfate Proteoglycan-4 Control the Growth of Multiple Solid Tumors both In Vitro and In Vivo
Authors: Geldres Claudia , Savoldo Barbara , Hoyos Valentina , Caruana Ignazio , Zhang Ming , Yvon Eric , Del Vecchio Michele , Creighton Chad J. , Ittmann Michael , Ferrone Soldano , Dotti Gianpietro
Published: April 2023

PDF file - 1277K, Immunohistochemistry of normal tissue arrays. Representative immunohistochemistry of normal tissue arrays. Endometrium, lung, skeletal muscle, nerve, skin, and a lung carcinoma are shown. 200X magnification.
Supplementary Figure 1 from T Lymphocytes Redirected against the Chondroitin Sulfate Proteoglycan-4 Control the Growth of Multiple Solid Tumors both In Vitro and In Vivo
Authors: Geldres Claudia , Savoldo Barbara , Hoyos Valentina , Caruana Ignazio , Zhang Ming , Yvon Eric , Del Vecchio Michele , Creighton Chad J. , Ittmann Michael , Ferrone Soldano , Dotti Gianpietro
Published: April 2023

PDF file - 624K, Patterns for CSPG4 expression in the Bittner dataset (www.oncomine.org, accessed June 10, 2013).
Supplementary Table 4 from MGMT-STP27 Methylation Status as Predictive Marker for Response to PCV in Anaplastic Oligodendrogliomas and Oligoastrocytomas. A Report from EORTC Study 26951
Authors: van den Bent Martin J. , Erdem-Eraslan Lale , Idbaih Ahmed , de Rooi Johan , Eilers Paul H.C. , Spliet Wim G.M. , den Dunnen Wilfred F.A. , Tijssen Cees , Wesseling Pieter , Sillevis Smitt Peter A.E. , Kros Johan M. , Gorlia Thierry , French Pim J.
Published: April 2023

Supplementary Table 4 - PDF file 69K, CpGs associated with benefit from adjuvant PCV chemotherapy
Supplementary Figure 2 from MGMT-STP27 Methylation Status as Predictive Marker for Response to PCV in Anaplastic Oligodendrogliomas and Oligoastrocytomas. A Report from EORTC Study 26951
Authors: van den Bent Martin J. , Erdem-Eraslan Lale , Idbaih Ahmed , de Rooi Johan , Eilers Paul H.C. , Spliet Wim G.M. , den Dunnen Wilfred F.A. , Tijssen Cees , Wesseling Pieter , Sillevis Smitt Peter A.E. , Kros Johan M. , Gorlia Thierry , French Pim J.
Published: April 2023

Supplementary figure 2 - PDF file 488K, Treatment effect included vs not included samples
Supplementary Figures from Molecular Classification of Malignant Pleural Mesothelioma: Identification of a Poor Prognosis Subgroup Linked to the Epithelial-to-Mesenchymal Transition
Authors: de Reyniès Aurélien , Jaurand Marie-Claude , Renier Annie , Couchy Gabrielle , Hysi Ilir , Elarouci Nabila , Galateau-Sallé Françoise , Copin Marie-Christine , Hofman Paul , Cazes Aurélie , Andujar Pascal , Imbeaud Sandrine , Petel Fabien , Pairon Jean-Claude , Le Pimpec-Barthes Francoise , Zucman-Rossi Jessica , Jean Didier
Published: April 2023

PDF file - 356KB, This file contains supplementary figures S1-S7. Figure S1: Flowchart depicting the analyses carried out to establish and validate a molecular classification of MPM; Figure S2: Unsupervised molecular subgroups in the discovery series; Figures S3: Recurrent regions of chromosomal alteration in MPM molecular subgroups; Figures S4: Identification of the three-gene predictor; Figure S5: Unsupervised molecular subgroups in the two public series; Figure S6: Distribution of histological subtypes and overall survival differences between MPM molecular subgroups in the two public series; Figure S7: Differential mRNA expression of epithelial-to-mesenchymal transition (EMT) markers in MPM molecular subgroups.
Supplementary Figure 2 from Margin-Infiltrating CD20+ B Cells Display an Atypical Memory Phenotype and Correlate with Favorable Prognosis in Hepatocellular Carcinoma
Authors: Shi Jie-Yi , Gao Qiang , Wang Zhi-Chao , Zhou Jian , Wang Xiao-Ying , Min Zhi-Hui , Shi Ying-Hong , Shi Guo-Ming , Ding Zhen-Bin , Ke Ai-Wu , Dai Zhi , Qiu Shuang-Jian , Song Kang , Fan Jia
Published: April 2023

PDF file - 439K, Flow-cytometry data from a representative patient showing that the majority of the CD20+ B cells are enriched in the tissue of the margin area.
Supplementary Figure 3 from JMJD2B Promotes Epithelial–Mesenchymal Transition by Cooperating with β-Catenin and Enhances Gastric Cancer Metastasis
Authors: Zhao Li , Li Wenjuan , Zang Wen , Liu Zhifang , Xu Xia , Yu Han , Yang Qing , Jia Jihui
Published: April 2023

PDF file - 127K, Supplementary Figure S3 JMJD2B inhibition attenuates TGF-Beta1-mediated Beta-catenin nuclear accumulation.
Supplementary Table 4 from Identification of Lethal microRNAs Specific for Head and Neck Cancer
Authors: Lindenbergh-van der Plas Marlon , Martens-de Kemp Sanne R. , de Maaker Michiel , van Wieringen Wessel N. , Ylstra Bauke , Agami Reuven , Cerisoli Francesco , Leemans C. René , Braakhuis Boudewijn J.M. , Brakenhoff Ruud H.
Published: April 2023

PDF file, 437K, Genes predicted to have potential binding sites for the six tumor-slective lethal microRNAs.
Supplementary Table 3 from Identification of Lethal microRNAs Specific for Head and Neck Cancer
Authors: Lindenbergh-van der Plas Marlon , Martens-de Kemp Sanne R. , de Maaker Michiel , van Wieringen Wessel N. , Ylstra Bauke , Agami Reuven , Cerisoli Francesco , Leemans C. René , Braakhuis Boudewijn J.M. , Brakenhoff Ruud H.
Published: April 2023

PDF file, 711K, Differentially expressed genes group B microRNAs.
Supplementary Table 1 from Identification of Lethal microRNAs Specific for Head and Neck Cancer
Authors: Lindenbergh-van der Plas Marlon , Martens-de Kemp Sanne R. , de Maaker Michiel , van Wieringen Wessel N. , Ylstra Bauke , Agami Reuven , Cerisoli Francesco , Leemans C. René , Braakhuis Boudewijn J.M. , Brakenhoff Ruud H.
Published: April 2023

PDF file, 107K, Data of primary screen.
Supplementary Figure 3 from Inactivation or Loss of TTP Promotes Invasion in Head and Neck Cancer via Transcript Stabilization and Secretion of MMP9, MMP2, and IL-6
Authors: Van Tubergen Elizabeth A. , Banerjee Rajat , Liu Min , Broek Robert Vander , Light Emily , Kuo Shiuhyang , Feinberg Stephen E. , Willis Amanda L. , Wolf Gregory , Carey Thomas , Bradford Carol , Prince Mark , Worden Francis P. , Kirkwood Keith L. , D'Silva Nisha J.
Published: April 2023

PDF file - 4209K, Supplementary Figure S3 The CAM invasion assay was performed with GFP (green) expressing UM-SCC-1-shC and -shTTP cells placed onto the upper CAM of an 11-day-old chick embryo for two days. Tissue sections were prepared and specimens were stained with Collagen IV (red) and DAPI (blue). Images were taken on Olympus BX-51 fluorescent microscope and merged. Results are representative of 3 independent experiments. White arrows point to invasive islands.
Supplementary Figure 1 from Preclinical and Early Clinical Evaluation of the Oral AKT Inhibitor, MK-2206, for the Treatment of Acute Myelogenous Leukemia
Authors: Konopleva Marina Y. , Walter Roland B. , Faderl Stefan H. , Jabbour Elias J. , Zeng Zhihong , Borthakur Gautam , Huang Xuelin , Kadia Tapan M. , Ruvolo Peter P. , Feliu Jennie B. , Lu Hongbo , Debose LaKiesha , Burger Jan A. , Andreeff Michael , Liu Wenbin , Baggerly Keith A. , Kornblau Steven M. , Doyle L. Austin , Estey Elihu H. , Kantarjian Hagop M.
Published: April 2023

PDF file - 131KB, Effects of MK-2206 on AKT signaling in FLT3-mutant AML cells.
Figure S6 from Consistent and Differential Genetic Aberrations between Esophageal Dysplasia and Squamous Cell Carcinoma Detected By Array Comparative Genomic Hybridization
Authors: Shi Zhi-Zhou , Shang Li , Jiang Yan-Yi , Hao Jia-Jie , Zhang Yu , Zhang Tong-Tong , Lin De-Chen , Liu Shu-Guang , Wang Bo-Shi , Gong Ting , Zhan Qi-Min , Wang Ming-Rong
Published: April 2023

Effect of ANO1 on cell proliferation. Knock-down the expression of ANO1 inhibited the cell proliferation of KYSE30 (A) and KYSE510 cells (B). The absorbance at 450 nm was measured.
Supplementary Figure 4 from Oncogenic Function of SCCRO5/DCUN1D5 Requires Its Neddylation E3 Activity and Nuclear Localization
Authors: Bommeljé Claire C. , Weeda Víola B. , Huang Guochang , Shah Kushyup , Bains Sarina , Buss Elizabeth , Shaha Manish , Gönen Mithat , Ghossein Ronald , Ramanathan Suresh Y. , Singh Bhuvanesh
Published: April 2023

PDF file - 76K, Kaplan-Meier survival curves from post-hoc analysis showing recurrence-free survival based on SCCRO5 mRNA expression status in primary lung neuroendocrine carcinomas.
Supplementary Figure 3 from Oncogenic Function of SCCRO5/DCUN1D5 Requires Its Neddylation E3 Activity and Nuclear Localization
Authors: Bommeljé Claire C. , Weeda Víola B. , Huang Guochang , Shah Kushyup , Bains Sarina , Buss Elizabeth , Shaha Manish , Gönen Mithat , Ghossein Ronald , Ramanathan Suresh Y. , Singh Bhuvanesh
Published: April 2023

PDF file - 56K, Correlation between SCCRO5 copy number alterations and mRNA expression measured by RNA seq (deep sequencing for RNA), in head and neck squamous cell carcinomas from The Cancer Genome Atlas, normalized by z-score transformation. Het, heterozygous; Hom, homologous; RPKM, reads per kilobase for million mapped reads.
Figure S2 from Consistent and Differential Genetic Aberrations between Esophageal Dysplasia and Squamous Cell Carcinoma Detected By Array Comparative Genomic Hybridization
Authors: Shi Zhi-Zhou , Shang Li , Jiang Yan-Yi , Hao Jia-Jie , Zhang Yu , Zhang Tong-Tong , Lin De-Chen , Liu Shu-Guang , Wang Bo-Shi , Gong Ting , Zhan Qi-Min , Wang Ming-Rong
Published: April 2023

Amplification and overexpression of MCM7 in ESCC. A. Amplification of MCM7 in array CGH study. B. Validation of MCM7 amplification by FISH. Left: two MCM7 signals in peripheral blood cells; Middle: two MCM7 signals in ESCC cells; Right: more than four MCM7 signals in ESCC cells. C. MCM7 overexpressed in ESCC by semi-quantitative RT-PCR. D. MCM7 overexpressed in ESCC by Western blotting. E. MCM7 overexpressed in ESCC by IHC.
Supplementary Figure 2 from BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma
Authors: Frederick Dennie T. , Piris Adriano , Cogdill Alexandria P. , Cooper Zachary A. , Lezcano Cecilia , Ferrone Cristina R. , Mitra Devarati , Boni Andrea , Newton Lindsay P. , Liu Chengwen , Peng Weiyi , Sullivan Ryan J. , Lawrence Donald P. , Hodi F. Stephen , Overwijk Willem W. , Lizée Gregory , Murphy George F. , Hwu Patrick , Flaherty Keith T. , Fisher David E. , Wargo Jennifer A.
Published: April 2023

PDF file - 349K, Inhibition of BRAFV600E is not associated with a significant increase in HLA expression in patients with metastatic melanoma.
Supplementary Data 3 from Adoptive Transfer of Autologous T Cells Improves T-cell Repertoire Diversity and Long-term B-cell Function in Pediatric Patients with Neuroblastoma
Authors: Grupp Stephan A. , Prak Eline Luning , Boyer Jean , McDonald Kenyetta R. , Shusterman Suzanne , Thompson Edward , Callahan Colleen , Jawad Abbas F. , Levine Bruce L. , June Carl H. , Sullivan Kathleen E.
Published: April 2023

PDF file - 209K, B cell maturation was defined by flow cytometry
Supplementary Figure 7 from Combined Immunostimulatory Monoclonal Antibodies Extend Survival in an Aggressive Transgenic Hepatocellular Carcinoma Mouse Model
Authors: Morales-Kastresana Aizea , Sanmamed Miguel F. , Rodriguez Inmaculada , Palazon Asis , Martinez-Forero Ivan , Labiano Sara , Hervas-Stubbs Sandra , Sangro Bruno , Ochoa Carmen , Rouzaut Ana , Azpilikueta Arantza , Bolaños Elixabet , Jure-Kunkel Maria , Gütgemann Ines , Melero Ignacio
Published: April 2023

PDF file - 953K, TILs recognize unknown antigens in JMJ cell lines.
Supplementary Figure 3 from Impairment of Glioma Stem Cell Survival and Growth by a Novel Inhibitor for Survivin–Ran Protein Complex
Authors: Guvenc Hacer , Pavlyukov Marat S. , Joshi Kaushal , Kurt Habibe , Banasavadi-Siddegowda Yeshavanth K. , Mao Ping , Hong Christopher , Yamada Ryosuke , Kwon Chang-Hyuk , Bhasin Deepak , Chettiar Somsundaram , Kitange Gaspar , Park In-Hee , Sarkaria Jann N. , Li Chenglong , Shakhparonov Mihail I. , Nakano Ichiro
Published: April 2023

PDF file - 4581K, Design of new Survivin inhibitors (related to Figure 3)
Supplementary Figure S3 from T-cell Responses to Oncogenic Merkel Cell Polyomavirus Proteins Distinguish Patients with Merkel Cell Carcinoma from Healthy Donors
Authors: Lyngaa Rikke , Pedersen Natasja Wulff , Schrama David , Thrue Charlotte Albæk , Ibrani Dafina , Met Özcan , thor Straten Per , Nghiem Paul , Becker Jürgen C. , Hadrup Sine Reker
Published: April 2023

PDF file 44K, LTA/STA responses in relation to MCPyV status
Supplementary Figure 4 from ALKBH3 Contributes to Survival and Angiogenesis of Human Urothelial Carcinoma Cells through NADPH Oxidase and Tweak/Fn14/VEGF Signals
Authors: Shimada Keiji , Fujii Tomomi , Tsujikawa Kazutake , Anai Satoshi , Fujimoto Kiyohide , Konishi Noboru
Published: April 2023

PDF file, 196K, The immunohistochemistry data for NOX2 in human urothelial carcinomas of the urinary bladder indicate a correlation with pathological parameter.
Supplementary Table S5 from Preclinical Antitumor Activity of Cabazitaxel, a Semisynthetic Taxane Active in Taxane-Resistant Tumors
Authors: Vrignaud Patricia , Sémiond Dorothée , Lejeune Pascale , Bouchard Hervé , Calvet Loreley , Combeau Cecile , Riou Jean-François , Commerçon Alain , Lavelle François , Bissery Marie-Christine
Published: April 2023

Supplementary Table S5 - PDF file 68K, In vitro antiproliferative effects of cabazitaxel against cell lines resistant to standard clinical agents not expressing P-glycoprotein
Supplementary Table 1 from Phosphoinositide 3-Kinase (PI3K) Pathway Alterations Are Associated with Histologic Subtypes and Are Predictive of Sensitivity to PI3K Inhibitors in Lung Cancer Preclinical Models
Authors: Spoerke Jill M. , O'Brien Carol , Huw Ling , Koeppen Hartmut , Fridlyand Jane , Brachmann Rainer K. , Haverty Peter M. , Pandita Ajay , Mohan Sankar , Sampath Deepak , Friedman Lori S. , Ross Leanne , Hampton Garret M. , Amler Lukas C. , Shames David S. , Lackner Mark R.
Published: April 2023

XLSX file - 18K, PI3K pathway alterations in NSCLC FFPE tumor samples
Supplementary Figures 1 - 6 from Phosphoinositide 3-Kinase (PI3K) Pathway Alterations Are Associated with Histologic Subtypes and Are Predictive of Sensitivity to PI3K Inhibitors in Lung Cancer Preclinical Models
Authors: Spoerke Jill M. , O'Brien Carol , Huw Ling , Koeppen Hartmut , Fridlyand Jane , Brachmann Rainer K. , Haverty Peter M. , Pandita Ajay , Mohan Sankar , Sampath Deepak , Friedman Lori S. , Ross Leanne , Hampton Garret M. , Amler Lukas C. , Shames David S. , Lackner Mark R.
Published: April 2023

PDF file - 221K, S1 Selected regions of recurrent amplification in 52 NSCLC tumor samples profiled by array CGH; S2 (A), GISTIC analysis showing combined frequency and magnitude of PIK3CA amplification in NSCLC tumor samples with squamous (upper) or adenocarcinoma (lower) histology. (B), plot of PIK3CA mRNA compared with copy number at the PIK3CA locus from a panel of NSCLC frozen tumor samples; S3 (A), array CGH data from individual squamous NSCLC tumor samples showing focal amplification of the PIK3CA locus on chromosome 3 and (B), TaqMan qPCR copy number analysis for PIK3CA for adenocarcinoma and squamous NSCLC samples,as well as matched normal lung tissue; S4 FISH assay showing additional copies of PIK3CA and, to a lesser extent, the centromeric probe CEP3, in the NSCLC cell line Calu3; S5 Western blot of selected PI3K/mTOR pathway components in NSCLC cell lines; S6 Tumor growth inhibition plot showing in vivo efficacy in H460 xenografts treated with 1mg/kg or 2.5mg/kg daily of GDC-0980
Supplementary Figure 1 from First-in-Human, Phase I Dose-Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of RO5126766, a First-in-Class Dual MEK/RAF Inhibitor in Patients with Solid Tumors
Authors: Martinez-Garcia Maria , Banerji Udai , Albanell Joan , Bahleda Rastilav , Dolly Saoirse , Kraeber-Bodéré Françoise , Rojo Federico , Routier Emilie , Guarin Ernesto , Xu Zhi-Xin , Rueger Ruediger , Tessier Jean J. L. , Shochat Eliezer , Blotner Steve , Naegelen Valerie Meresse , Soria Jean-Charles
Published: April 2023

PDF file, 18K, Schematic showing cohort doses evaluated, dose-limiting-toxicities observed and maximum-tolerated-doses per dosing regimen.