bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role of the Supervisory Board in Finnish Cooperatives
Authors: Huhtala Kari
Published: January 2024

Research on the supervisory boards of cooperatives has been scarce considering their prevalence, especially in continental Europe. The supervisory board is a voluntary body under Finnish conditions and consists exclusively of members’ representatives. According to the cooperative law, the task of the supervisory board is to supervise the board and management. Based on the results of this article, the role of the supervisory board is changing in a more dynamic direction, which includes sparring with the board, taking care of the ownership strategy and developing interaction with the membership. Hence, it would fulfill not only the conformance role of the governance towards the membership but support the performance role of the board. This new role would require re-assessment of the selection criteria for the members of the supervisory board, not merely from a representational perspective, but also from the perspective of competence adequacy. The supervisory board and its chairperson are significant users of the power based on their formal position in preparing and electing directors. They also use the informal power in interaction with the board and its chairperson.Received: 28 April 2023 Accepted: 07 October 2023
Trendi na področju kadrovskega managementa
Authors: Jereb Eva
Published: January 2024

Prvo poglavje se osredotoča na pregled ključnih tehnoloških trendov na področju kadrovske funkcije pri delu na daljavo. Drugo poglavje obravnava težavne pogovore na delovnem mestu in ravnanje posameznikov, ko se z njimi soočijo. V tretjem poglavju so predstavljene kompetence za obvladovanje kompleksnih kriz. Četrto poglavje obravnava tehnologijo veriženja blokov na področju kadrovskega managementa. Peto poglavje prikazuje sistematični pregled zelenih kompetenc na področju zdravstva. Šesto poglavje nas popelje skozi zasnovo sistema ocenjevanja in nagrajevanja zaposlenih. Zadnje, sedmo poglavje, pa opozarja na pomen predporodnega izobraževanja in vpliv le tega na kvaliteto življenja po porodu in sam razvoj posameznika.
Pediatric lymphomatoid papulosis – a case report and management considerations
Authors: Dec Michał , Arasiewicz Hubert
Published: January 2024

Lymphomatoid papulosis (LyP) jest rzadką chorobą skóry, najczęściej obserwowaną u dorosłych, a jej występowanie
w populacji pediatrycznej jest niezwykle rzadkie. W pracy przedstawiono przypadek 6-letniego dziecka płci męskiej,
u którego stwierdzono cechy kliniczne i histopatologiczne zgodne z rozpoznaniem LyP. Na skórze pacjenta obserwowano liczne rumieniowe grudki zlokalizowane na tułowiu i kończynach, a towarzyszył im łagodny świąd. Zmiany chorobowe pojawiały się nawrotowo, następnie ustępowały i zmieniały morfologię. W badaniu przedmiotowym nie stwierdzono limfadenopatii ani objawów ogólnoustrojowych. W badaniu histopatologicznym w skórze właściwej stwierdzono gęsty naciek limfocytów atypowych z hiperchromatycznymi i nieregularnymi jądrami komórkowymi. Analiza immunohistochemiczna potwierdziła ekspresję CD30 w naciekających komórkach, co potwierdza rozpoznanie LyP.
W celu złagodzenia świądu i stanu zapalnego podawano miejscowo glikokortykosteroidy, chociaż uzyskano jedynie minimalne złagodzenie objawów. Korzystne efekty fototerapii wąskopasmowej UVB 311 obserwowano przez cztery miesiące. Niemniej jednak po zaprzestaniu leczenia zaobserwowano ponowne pojawienie się zarówno zmian guzkowych, jak i mniejszych zmian grudkowych. W związku z tym rozpoczęto schemat terapeutyczny polegający na podawaniu metotreksatu w dawce 10 mg raz na tydzień.
Leczenie LyP różni się zależnie od ciężkości zmian i objawów u pacjenta. Decyzje dotyczące leczenia należy dokładnie rozważyć ze względu na stosunkowo łagodny charakter choroby.
Rozpoznanie LyP u dzieci i młodzieży stanowi wyzwanie ze względu na rzadkość występowania choroby i możliwość błędnego rozpoznania tej jednostki chorobowej z chłoniakami złośliwymi. Histopatologia i immunohistochemia odgrywają kluczową rolę w odróżnianiu LyP od bardziej agresywnych jednostek chorobowych.
Pancasila and Citizenship Education Learning Model for Elementary School Students: A Literature Review
Authors: Retnasari Lisa , Hidayah Yayuk , Mulyoto Galih Puji , Istianah Anif
Published: January 2024

Model pembelajaran merupakan kerangka konseptual yang digunakan guru dalam mengorganisir pembelajaran. Model pembelajaran dianggap mampu mengatasi permasalahan yang timbul dalam proses pembelajaran terjadi. Model pembelajaran yang inovatif akan memudahkan dalam mencapai tujuan pembelajaran yang dirumuskan.Penelitian ini secara khusus bertujuan untuk mengetahui model pembelajaran PPKn SD. Jenis penelitian ini adalah kualitatif studi literatur. Hasil penelitian menunjukan bahwa model pembelajaran yang tepat dalam PPKn SD  ialah 1) Value Clarification Technique (VCT), 2) Analisis kasus, 3) Contextual Teaching and Learning (CTL), 4) Problem Based Learning (PBL).
Schooling From Home During Pandemic: How Do Parents' Response Towards Online Learning?
Authors: Hesmatantya Vega , Wijaya Armeria
Published: January 2024

This study aims to find the parents' response towards online schooling from home attended by their children. The spread of Covid-19 becomes a massive pandemic hazardous for the community. Its rapid transmission forces government to implement emergency policy to cope with this virus. The Ministry of Education and Culture decided to eliminate face-to-face learning on behalf of the Indonesian Government. The school is temporarily closed to disrupt a chain of Covid-19 transmission. As a replacement, face-to-face learning is transformed to be online learning. In this case, parents' roles become more prominent because they must provide learning assistance to their children to ensure that schooling from home can be followed properly. This exploratory research involved 200 parents as respondents to fill in the questionnaire, and later 12 parents were invited to proceed with further interview sessions. The result indicated a positive response to the implementation of online learning initiated by their schools. Its implementation is an appropriate option for preventing students from infectious Covid-19. However, some obstacles occur when parents cannot assist their children optimally due to their responsibility to accomplish their work and go to the office during school hours. It is suggested that teachers' assistance during learning from home can be improved to maintain effective learning. Moreover, parents hope that face-to-face school can be held right away after the pandemic is successfully handled.
Madrasah Teachers’ Self Efficacy on Constructing Literacy-Based Teaching Materials
Authors: Asmiyah Siti , Safriyani Rizka , Muhtarom Muhtarom
Published: January 2024

One of the most important teaching tasks is designing teaching materials professionally and accordingly constructed to support the teaching and learning process effectively. Thus, teachers need to be aware of selecting the appropriate material and learning resources for their students. This awareness is called self-efficacy which can be described as a person’s belief in their ability to succeed in a particular situation or task including teaching material preparation. Thus, this present research investigated the level of teachers’ self-efficacy in constructing a literacy-based teaching material. It employed mixed-method research, explanatory- sequential research. The respondents were 69 teachers of Madrasah Ibtidaiyah to Madrasah Aliyah in East Java. Surveys, interviews, and focus group discussions were used to collect data that was analyzed using SPSS 25. Further, the data was also described qualitatively based on the theme made. Then, the result shows the teachers’ self-efficacy in constructing literacy-based teaching material is on the intermediate level. Thus, implications and recommendations are given in this study.
The Phenomenon of Self-Diagnosis Behavior on Self-Healing Style in Young People
Authors: Ginting Eraskaita , Hati Putri Citra
Published: January 2024

The phenomenon of self-diagnosis, which is widely discussed on social media, has made many young people carry out self-healing in their way. This research aims to discover how self-diagnosis behavior affects the style of self-healing in young people and whether the concept of self-healing, which is popular among the younger generation, is by actual self-healing. This research method uses a qualitative descriptive approach with literature studies and data collection through secondary data obtained through literature studies such as reference books, journals, articles, and other sources related to research. The results of this research show that stigma and discrimination are still obstacles for mental health sufferers in getting appropriate and adequate treatment. This triggers the younger generation to carry out self-healing independently in their style, and this has an impact on the actual concept of healing. Several ways can be used as references for young people for self-healing, including mindfulness, guided imagery, self-talk, and expressive writing.
The Effect of Good Governance Practices and Decision Making at Da’wah and Communication Faculty UIN Raden Fatah Palembang
Authors: M. Ed Manalullaili
Published: January 2024

In the dynamic landscape of higher education, effective governance practices and decision-making within academic institutions are pivotal for shaping the academic environment. This holds particularly true for faculties dedicated to Da'wah and Communication, where religious principles, communication, and academic rigor converge. This study explores governance practices and decision-making dynamics within the Da’wah and Communication Faculty at UIN Raden Fatah Palembang. The research delves into administrative structures, decision-making processes, and their impact on academic, religious, and communicative dimensions. Differentiating educational governance from corporate governance, the study underscores the complexity of educational contexts. In the Da’wah and Communication Faculty, the Management Review Meeting serves as a crucial governance practice. The meeting involves agenda overview, prior meeting evaluation, academic contributions, student affairs, financial analysis, technology assessment, and open discussion. This strategic approach enhances organizational performance, aligning with the principles of good governance. The research methodology employs a quantitative approach, utilizing cross-sectional data from interviews and questionnaires. The Likert scale measures perceptions, with decision-making as the dependent variable and good governance as the independent variable. Hypothesis testing involves simple linear regression and partial tests. Research findings suggest a positive but statistically insignificant correlation between knowledge management (KM) and decision making (DM). Influencing factors include small sample sizes, high variability, insensitive measurement methods, unaccounted control variables, temporal aspects, and chance factors. Enhancing significance requires expanded sample sizes, detailed control variables, and robust statistical methods. Contextual considerations are crucial, emphasizing the context-dependent nature of the KM-DM relationship. In conclusion, the KM-DM relationship is generally perceived as positive, yet lacks consistent statistical significance. Factors influencing this relationship necessitate methodological improvements. Recognizing the context-dependent nature of KM's impact on decision-making outcomes, researchers can refine strategies for more targeted decision-making in educational organizations.
Framing Media Dan Dinamika Opini Publik TerkaitPengungsi Rohingya Di Indonesia: Perspektif UNHCR Dan Otoritas Aceh Dalam Sorotan Kritis
Authors: Mamis Subria , Rustan Ahmad Sultra , Arnus Sri Hadijah , Basri Hasan
Published: January 2024

Penelitian ini menganalisis framing media terkait penolakan dan penerimaan Rohingya sebagai pengungsi di Indonesia. Penelitian berfokus pada framing liputan berita yang dikeluarkan UNHCR dan Pemerintah Kabupaten Aceh (Pemkab Aceh), serta media lain yang secara eksplisit menyuarakan penolakan terhadap kehadiran Rohingya. Analisis konten digunakan sebagai pendekatan utama untuk menyelidiki bagaimana isu ini disajikan dan diekplorasi lebih jauh dalam media sehingga perbedaan media teramati dalam menggambarkan topik ini. Hasil penelitian menunjukkan bahwa UNHCR memandang Rohingya sebagai entitas yang berhak diterima di Aceh, berdasarkan prinsip-prinsip Hak Asasi Manusia dan keyakinan bahwa kehadiran mereka tidak akan mengeksploitasi kondisi di Aceh. Di sisi lain, framing berita yang menolak kehadiran Rohingya berasal dari alasan justifikasi ketidakpartisipan Indonesia dalam penandatanganan konvensi pengungsi, yang diartikan sebagai dasar bahwa Indonesia tidak berkewajiban menerima Rohingya. Alokasi Anggaran Pendapatan dan Belanja Daerah (APBD) Aceh untuk penanganan bencana banjir memperkuat alasan penolakan, didampingi dengan tuntutan tegas dari Pemerintah Kabupaten Aceh kepada pemerintah Indonesia untuk merespons kebijakan ini. Urgensi penelitian ini terletak pada kebutuhan akan pemahaman mendalam terhadap dinamika framing media yang mampu membentuk opini publik dan memengaruhi kebijakan pemerintah terkait isu kemanusiaan dalam konteks lokal, regional, bahkan internasional.
Problemas interpretativos de la definición estoica de representación cognitiva
Authors: Pineda Christian
Published: January 2024

El objetivo de este artículo es mostrar cuáles son y en qué consisten los problemas interpretativos de la definición estoica de representación cognitiva (καταληπτική φαντασία). Para tal fin, propongo una reconstrucción del debate académico sobre esta definición. Dicha reconstrucción articula el debate entorno a sus dos términos más problemáticos: el participio ὑπάρχον y la preposición ἀπό. A partir de un análisis de los fragmentos estoicos en los que aparecen estos términos, exploro las razones tanto filosóficas como textuales a favor y en contra de cada uno de los diferentes sentidos de ἀπό y cada una de las diferentes acepciones de ὑπάρχον. Al hacer esto, me propongo evidenciar las limitaciones de las interpretaciones de la definición de representación cognitiva que se han propuesto. Basándome en este examen, propongo en las conclusiones una serie de cuestiones centrales que deben formar parte de la agenda de investigación sobre la definición estoica de representación cognitiva. De esta manera, pueden observarse los retos que supone defender una interpretación determinada y, en cierta medida, podrían también vislumbrarse posibles soluciones.
Caminhos para a proteção da dignidade da pessoa humana na sociedade de dados
Authors: Melo Renan , Alvim Marcia Cristina de Souza
Published: January 2024

O presente artigo tem como escopo analisar a proteção jurídica à dignidade da pessoa humana no seio da sociedade de dados. O objetivo principal é tratar de como preservar a dignidade da pessoa humana no contexto em que as interações humanas estão cada mais permeadas pelas novas tecnologias de big data pelo e ambiente digital. O presente trabalho tem sua importância justificada na assimilação dos novos padrões de interação social e a proteção jurídica a ser conferida no novo contexto social. A metodologia empregada na construção deste artigo foi a lógico-dedutiva, com base no procedimento de análise bibliográfica sobre os pontos centrais envolvendo a sociedade de dados, o campo digital e a defesa da dignidade da pessoa humana.
O direito como "aparelho ideológico de Estado": notas sobre Louis Althusser e seus críticos
Authors: Villas Bôas Filho Orlando
Published: January 2024

O presente artigo tem por objetivo analisar a tese de Louis Althusser acerca do direito como “aparelho ideológico de Estado” e algumas críticas que lhe são dirigidas. Para tanto, em primeiro lugar, enfoca aspectos gerais da teoria althusseriana que sustentam a sua compreensão do Estado como instrumento de dominação de classe. Em seguida, analisa a teoria althusseriana dos “aparelhos ideológicos de Estado” para, a partir dela, abordar o direito como “aparelho de Estado”. Por fim, examina concisamente quatro perspectivas (a de Nicos Poulantzas, a de Michel Miaille, a de Pierre Bourdieu e a de Jacques Commaille) que, a partir de ângulos distintos, criticam a tese de Louis Althusser. A sua hipótese é de que essas críticas permitem uma compreensão mais efetiva da teoria althusseriana do direito como “aparelho de Estado”. A metodologia empregada é híbrida, de caráter descritivo-bibliográfico-explicativo. Como resultado, o artigo proporciona uma discussão crítica da teoria althusseriana do direito como “aparelho de Estado”.
Sobre a curricularização da extensão nos projetos pedagógicos dos cursos de Direito
Authors: Hogemann Edna Raquel
Published: January 2024

Este artigo vale-se da leitura crítico-reflexiva dos projetos pedagógicos dos cursos de Direito de duas instituições de ensino brasileiras para promover uma reflexão que perquire o nível de eficácia objetiva na aplicação das políticas públicas voltadas para a curricularização da extensão universitária, consagradas na Resolução do MEC n° 7 de 2018, artigo 4°. Vale-se da abordagem quanti-qualitativa e objetivos exploratórios, a partir do método hipotético-dedutivo, tendo em conta a necessidade de reinterpretação dos dados obtidos do cotejo das duas experiências pedagógicas. Aponta para o fato das duas experiências serem demarcadas por soluções muito próprias e lança luzes sobre as possibilidades da curricularização da extensão jurídica implantada no País e as possibilidades existentes, a partir da implementação de uma extensão universitária vocacionada para a cidadania, culminando por reconhecer a consagração desse intento por ambas as instituições de ensino superior.
O fomento do financiamento da inovação por meio das debêntures incentivadas
Authors: Morettini Felipe Tadeu Ribeiro
Published: January 2024

O presente artigo objetiva analisar a atuação fomentadora do Estado para o financiamento da produção econômica intensiva em pesquisa, desenvolvimento e inovação (PD&I) por meio das debêntures incentivadas instituídas pela Lei no 12.431/2011, ante os problemas de desenvolvimento do setor. Considera-se a hipótese de sua efetividade, uma vez que foi este o objetivo estimado quando de sua criação. A metodologia utilizada parte de uma perspectiva descritiva e indutiva, incorporando uma análise funcionalista do instrumento para avaliar sua efetividade frente às políticas públicas para inovação no Brasil, com a utilização da pesquisa descritiva bibliográfica e do levantamento de dados. Chega-se à conclusão de que as debêntures incentivadas criadas pela Lei no 12.431/2011, apesar de possuírem um formato jurídico adequado para o desenvolvimento de PD&I em países em desenvolvimento, careceram de articulação com uma política pública adequada que lhes dessem suporte, mostrando-se pouco efetivas no período analisado.
A garantia do exercício do direito à saúde como reflexo da cidadania
Authors: Silva Anna Paula Soares da , Lima Fernando Rister de Sousa
Published: January 2024

Este trabalho apresenta uma análise sobre a relação médico-paciente e a garantia da autodeterminação informativa pela legislação como reflexo direto do exercício da cidadania. Com efeito, o objetivo principal do artigo é demonstrar que se diretrizes legais elaboradas pelo Estado fizeram com que, ao longo dos anos, fosse possibilitado ao paciente exercer a sua cidadania de forma mais equânime. A metodologia utilizada será a pesquisa doutrinária e legislativa, por meio do método de procedimento bibliográfico e argumentativo. Como resultados alcançados, entendemos que as diretrizes legais estabelecidas após a promulgação da Constituição Federal foram determinantes para que os pacientes, ao obter o direito social à saúde em sua plenitude, em especial razão por conta das garantias que tais normativas estatais proporcionaram, teve verdadeira concretização de sua cidadania por meio de mecanismos de autodeterminação, em especial a informativa.
Intent to destroy no crime de genocídio: conhecimento e domínio das condutas individualmente consideradas dentro de um contexto genocidário e a atuação política brasileira na pandemia
Authors: Brito Alexis Couto de , Almeida Stéphanie Havir de
Published: January 2024

Cientes da dificuldade em representar e verificar os elementos que configuram o dolo, especialmente quanto ao crime de genocídio, e em meio às discussões acerca da adequação típica das condutas de dirigentes nacionais adotadas durante a Pandemia de Covid-19, buscamos, no presente estudo, apresentar uma alternativa às teorias existentes para identificação dos quesitos que constituem o intent to destroy, elemento essencial do tipo do crime de genocídio, conforme redação da Convenção para Prevenção e Repressão do Crime de Genocídio, replicada no Estatuto de Roma. De forma dialética, por meio da combinação de duas teorias propostas para a verificação e caracterização do dolo: a Twice Twofold Structure proposta por Kai Ambos, e a Teoria Cognitiva do Dolo na linha proposta por Ingeborg Puppe e compartilhada por Luís Greco, que toma o conceito de vontade no sentido atributivo-normativo, em contraste com o conceito psicológico-descritivo adotado pelas tradicionais teorias volitivas do dolo, apresentou-se uma terceira teoria capaz de melhor demonstrar o special intent/dollus specialis/dolo especial, que é requisito à verificação da conduta dolosa, única forma admissível de comissão do crime de genocídio. Na sequência, analisamos a alardeada suposta prática de genocídio por dirigentes nacionais na condução das políticas públicas de combate à pandemia de Covid-19, especialmente no estado do Amazonas, tomando por base o Relatório Final votado pela Comissão Parlamentar de Inquérito da Pandemia, em 26 de outubro de 2021, deduzindo pela possível prática de genocídio em face apenas de populações indígenas, já que para os demais casos mostraram-se ausentes diversos requisitos intrínsecos tanto ao conceito de genocídio quanto à teoria ora elaborada.
Judicial limits over the administrative discretionary act: analysis of the decisions of the injunctions granted in aco 3.451/DF by the Brazilian Supreme Court
Authors: Azevedo Edgar Meira Pires de , D’Assunção Maria Esther Alencar Advíncula , Presgrave Ana Beatriz Ferreira Rebello
Published: January 2024

The serious health situation resulting from the Covid-19 pandemic, in addition to the global health emergency, also generated deep crises in the economic, political-ideological and governance fields, which led to the Judiciary several issues that, in a normal situation, would not be within its jurisdiction. Therefore, this paper aims to address the decision rendered by the Federal Supreme Court (STF) in ACO 3.451/DF, in which the Court allowed the automatic authorization for the State of Maranhão to import and distribute the Sputnik V vaccine for its population. Consequently, the central problem of this research is to analyze whether this position, in addition to promoting a re-reading of the control of the administrative act by the Judiciary, is in accordance with the constitutional provisions. This is a research of strategic basic purpose, descriptive and exploratory objective, under the deductive method, with a qualitative approach and performed through bibliographic and documental procedures. In the end, it is verified that the decision taken by the STF in the judgment of ACO 3451/DF affronts the principle of the functional division of power, expressed in art. 2 of the Federal Constitution, and also culminates in violating the right to health itself, set forth in art. 196 of the Constitution. Moreover, the greatest contribution of the research is, precisely, in enabling the discussion of the position adopted by the Court before the ineffective management of the Executive due to the health crisis that has been established with the Covid-19 pandemic.
A experiência de adoção entre casais homoafetivos e heteroafetivos: aproximações e distanciamentos
Authors: Berres Angélica Nelice dos Anjos , Gomide Paula Inez Cunha , Azevêdo Adriano Valério dos Santos
Published: January 2024

No Brasil, a adoção de crianças/adolescentes é um direito concedido para casais homoafetivos e heteroafetivos, porém, podem surgir dificuldades e estigmas sociais. Este artigo objetivou analisar as aproximações e distanciamentos entre casais homoafetivos e heteroafetivos adotantes referentes aos seguintes pontos: 1) motivações para a adoção; 2) aspectos facilitadores e dificultadores da adoção; 3) a rotina do casal antes e após à adoção; 4) relacionamento do casal e filhos com a escola; e 5) casais homoafetivos e o preconceito. Utilizou-se o método qualitativo com a hipótese de que as práticas parentais eram similares para ambos os grupos. Foram entrevistados 64 pais e mães, divididos em dois grupos: 1. Homoafetivos – 38 pessoas, sendo 19 casais (nove de lésbicas e dez de gays), 2. Heteroafetivos – 26 pessoas, sendo 13 casais. A comparação entre os dois grupos mostrou similaridades em relação às motivações, as dificuldades para obtenção dos novos registros de nascimento e falta de acompanhamento psicológico pelo poder judiciário. Em ambos os grupos, a parentalidade é exercida por meio do diálogo e divisão nas tarefas domésticas e escolares. Os distanciamentos se referem aos casais homoafetivos: 1.lentidão e preconceitos durante o processo de adoção e inserção/adaptação dos filhos na escola, 2. falta de calendários adequados para festejar dia dos pais/mães. Maiores obstáculos são enfrentados pelos casais homoafetivos, assim, destaca-se a necessidade de mudanças no sistema judiciário para permitir a garantia de assistência integral buscando legitimar o direito à cidadania.
Studying the pharmacological safety of the standardized cleared bischofit brine
Authors: Bugaeva Lyubov I. , Spasov Alexander A. , Lebedeva Svetlana A. , Korzhova Tatyana M. , Getmanenko Andrey Yu.
Published: January 2024

In experiments on mature rats, the pharmacological safety of a purified form of a standardized brine of the mineral bischofite (SBB) was assessed with repeated intragastric administration for 90 days at a dose of 0.01 ml/kg (experimentally proven therapeutic dose). It has been established that the test substance does not have a damaging effect on the general condition of animals (body weight, coat and skin, behavior), hematological and biochemical blood parameters, electrophysiological work of the myocardium, liver and kidney function, does not contribute to changes in the morphostructure of internal organs and brain. In the action of SBB with repeated 90-day administration, the effects of gender differences in behavioral activity (increase in motor and emotional activity in males and decrease in such effects in females) were revealed, electrocardiogram (increased heart rate and amplitude of the "R" wave in males and no changes in females), biochemical parameters (increased glucose levels in males and no changes in females). These changes did not go beyond the physiological norm and completely leveled to the state of control during the 30-day withdrawal of SRP administration.
The clinical case of the patient’s treatment with avascular necrosis of the femoral and tibiral condyles by the method of intraosseous injection of autological bone marrow aspirate concentrate
Authors: Kondrashenko Vladimir V. , Malanin Dmitry A. , Demeshchenko Maxim V. , Perfilova Valentina N. , Borisov Alexander V.
Published: January 2024

According to statistics, from 5 to 17 % of endoprothesis is performed for avascular necrosis. This article demonstrates the use of autologous bone marrow aspirate concentrate as an orthobiological material in the treatment of developed stage 2 avascular necrosis while taking glucocorticosteroids for Covid-19 applying the example of a clinical case. The patient’s complaints, the results of laboratory and instrumental investigations, the technique for performing intraosseous injection are described. The functional state of the knee joint was assessed before treatment and after 3, 6 and 12 months. The case study testifies to the effectiveness of the use of an orthobiological preparation and explains the need for further study of the presented methodic.
HUBUNGAN MANAJEMEN WAKTU BELAJAR DENGAN PRESTASI BELAJAR MENUJU ERA SOCIETY 5.0 [THE RELATIONSHIP OF STUDY TIME MANAGEMENT WITH LEARNING ACHIEVEMENT TOWARDS THE ERA OF SOCIETY 5.0]
Authors: Nurlaila Nugraheni , Rigianti Henry Aditia
Published: January 2024

Studying time management is the management of learning opportunities. This governance is very important as an effort to improve learning achievement. The method used by researchers is literature review. From this research and literature review, results include that students who manage training duration are able to achieve or increase training manifestations substantially. By managing the training period, students become more determined in carrying out training.

 

Bahasa Indonesia Abstrak

Manajemen waktu belajar merupakan tata kelola kesempatan dalam belajar. Tata Kelola ini sangat penting sebagai upaya meningkatkan prestasi belajar. Metode yang peneliti tempuh ialah kajian literatur. Dari penelitian dengan kajian pustaka ini membuahkan hasil antara lain siswa yang melakukan pengelolaan durasi pelatihan mampu meraih atau meningkatkan manifestasi pelatihan dengan substansial. Dengan melakukan pengelolaan masa pelatihan, siswa menjadi lebih bertekat dalam melakukan pelatihan.
Orthognathic surgery in a patient with von Willebrand disease
Authors: Barcellos Bhárbara Mariano , Moreira Andressa Goicochea , Silveira Isabela Toledo Teixeira da , Gomes Eduardo de Freitas , Xavier Cristina Braga , Chagas Júnior Otacílio Luiz
Published: January 2024

Aim: This study aims to report the perioperative management of a patient with von Willebrand disease (vWd) who underwent orthognathic surgery. The report follows the guidelines of the Case Report Guidelines (CARE) and focuses on the steps taken to prevent bleeding during the surgical procedure. Methods: A 39-year-old female patient with skeletal Class III was treated with maxillary advancement and mandibular setback. Despite normal test results for ristocetin cofactor activity, measures were taken to prevent bleeding, including atraumatic surgical techniques, use of antifibrinolytic medication, induced hypotension during anesthesia, and preparation of blood products for transfusion during trans and postoperative periods if needed. In the end, these measures were not required. Results: The patient did not experience any bleeding during the surgical procedure or postoperative period, demonstrating the effectiveness of the measures taken to manage their blood dyscrasia. Two years after the surgery, the patient had satisfactory aesthetic and functional results and no evidence of relapse. Conclusion: Thus, this case report demonstrates that vWd does not prevent largescale oral and maxillofacial surgeries such as orthognathic surgery as long as proper precautions are taken pre-, intraand postoperatively.
The challenges facing mathematics teachers in Sahab Governorate schools after the COVID-19 pandemic and the plans to address them
Authors: Abuzaid Hana' Shihdah Mosleh
Published: January 2024

The study aimed to investigate the challenges facing mathematics teachers as a result of educational waste after the COVID-19 pandemic and the remedial plans for it by enhancing cognitive achievement from the perspective of teachers in schools affiliated with the education of Sahab Governorate. The descriptive analytical approach was adopted, and a questionnaire tool was developed to obtain data from the study sample, consisting of (200) mathematics teachers from Sahab Governorate. The study results showed that the difficulties faced by mathematics teachers due to educational waste after the COVID-19 pandemic were high, with an average of (4.56). One of the most important methods, according to teachers, to address these difficulties was diversifying the teaching methods suitable for students, such as boards, models, and others. As a result, the study recommended several recommendations, the most important of which was expanding the scope of future studies and understanding the effects of educational waste after the COVID-19 pandemic in other contexts.
AIMS65 Scoring System for Predicting Clinical Outcomes Among Emergency Department Patients with Upper Gastrointestinal Bleeding
Authors: Nabiel Rifaldy , Munawir Al , Firdaus Jauhar
Published: January 2024

Introduction: Several scoring systems were developed for early risk stratification in Upper Gastrointestinal Bleeding (UGIB) patients. AIMS65 score is a scoring system that only consists of five parameters, it might be used in daily clinical practice because of rapid and easy to calculate within 12 hours of admission. Objective: To evaluate the AIMS65 scoring system as a predictor of mortality, rebleeding events, need for endoscopic therapy, blood transfusion, and ICU admission for all causes of UGIB. Methods: We conducted a systematic review on PubMed, ScienceDirect, ProQuest, and Cochrane Library databases from the 2012 to 2022 publication period. We included either prospective or retrospective cohort studies that reported UGIB with all kinds of aetiologies who presented in the emergency department (ED), reported discriminative performance for each outcome, and reported the optimal cut-off of AIMS65. The primary measurement of discriminative performance for clinical outcomes includes mortality, rebleeding incidents, need for endoscopic therapy, blood transfusion, and ICU admission. Results: We identified 351 published studies, of which 20 were included in this study. Most of the studies reported discriminative performance for predicting mortality, which amounts to about 18 out of 20 studies. Rebleeding prediction was reported in 11 studies, need for endoscopic therapy in 5 studies, blood transfusion in 7 studies, and ICU admission in 2 studies. Most of the studies reported fair to excellent discriminative performance for predicting mortality, but in contrast for predicting rebleeding, the need for endoscopic therapy, blood transfusion, and ICU admission. Cut-off values≥ 2 are frequently reported to distinguish between high-risk and low-risk patients in mortality. Conclusion: AIMS65 can be applied to patients with UGIB in ED for predicting mortality, but not applicable for predicting rebleeding events, the need for endoscopic therapy, blood transfusion, and ICU admission. It enhances early decision-making and triage for UGIB patients.
Xanthophore Distribution of Nemo (Amphiprion ocellaris) Skin Based on various Concentrations of Carotenoid Sources
Authors: Pratiwi Rini , Karim Muhammad Yusri , Trijuno Dody Dh
Published: January 2024

Abstract
The decreased color intensity of  Nemo is related to the amount of carotenoid concentration in the xanthophore of Nemo’s skin. Therefore, efforts are needed to maintain stable carotenoid production. Tomato is one of the most abundant carotenoid producers. The utilization of carotenoids can maintain the morphological color of aquatic organisms. This study aimed to analyze the effect of carotenoid compounds on total carotenoid content, the size, and distribution of xanthophores on Nemo skin. A total of 60 Nemo with an average initial weight of 0.84±0.14 g and an average length of 2.95±0.08 cm. The research was conducted using a completely randomized design (CRD), consisting of four carotenoid concentrations in addition to fish pellet, 0%, 0.5%, 1%, and 1.5% with three replications. The results showed that the optimum dose of carotenoid compounds in increasing the total carotenoid content in nemo fish skin is 1.5%. Carotenoids added to the fish feed affected the distribution and maturity of xanthophore. However, it did not affect the size of the xanthophore.
Highlight Research

Nemo contains three types of pigment cells, namely melanophores, xanthophores, and iridophores.
Carotenoid supplementation is related to xanthophore in fish skin
The pigment pattern is determined mainly by the number, size, and distribution of different cell types
xanthophores were not found in the histology HE (hematoxylin-eosin) staining method in fish skin.
Optimizing Coastal Management: A Comprehensive Value Chain Analysis Approach for Sustainable Economic Development in Java, Indonesia
Authors: Rozaki Zuhud , Ariffin Ahmad Shabudin , Ramli Mona Fairuz , Nurrohma Elvina , Ramadhani Novara Nurvinka , Setyoasih Winda Ismah , Senge Masateru
Published: January 2024

Abstract
Coastal areas have become an important part of Indonesia's evolving economy, with a variety of commercial activities taking place. The island of Java has both northern and southern coastal areas, each with its own distinctive characteristics and products. The studies about coastal development through its product value chain are still limited. This study aimed to determine the value chain of fishery products in Java to provide recommendations for enhancing coastal management. For the northern coast, milkfish and ariid catfish from Juwana Coast (Pati Regency, Central Java) were selected, while Whiteleg Shrimp from Mendit Coast and Trisik Coast of Kulon Progo Regency, Yogyakarta were chosen to represent the southern coast. The study involved 48 respondents, including small and medium-sized enterprises (SMEs), farmers, fishermen, wholesalers, middlemen, retailers, restaurants, and consumers. The analysis techniques used in this study included Porter’s value chain, Hayami’s added value, Return/Cost (R/C) Ratio, and marketing margin analysis. The results of the study revealed that the products followed various channels in the value chain, with longer chains leading to higher prices for the end consumers. The findings also indicated that processed and creatively packaged products tend to command higher prices and generate greater profits. Coastal management should not only focus on upstream activities but also consider downstream processes to increase the value of coastal products. Efforts to enhance coastal management should consider key actors and government interventions through developing the coastal local products.
Highlight Research

The coastal area of Java Island makes a significant contribution to the local economy.
The supply chain of Whiteleg Shrimp, Ariid Catfish, and Milkfish involves various actors who play important roles in maintaining the distribution of coastal products.
Value chain analysis reveals opportunities to increase and improve the quality of products to enhance their worth.
It is necessary to enhance coastal management by involving local institutions, the government, and the private sector.
Social Structure Analysis in Management of South Sumatra Inland Waters
Authors: Putri Fevi Rahma Dwi , Satria Arif , Kinseng Rilus A. , Taryono Taryono
Published: January 2024

Abstract
The social structure of inland fisheries communities tends to place powerful elites in important positions, while local fishermen are subordinate actors. Patronage is a form of social relationship that describes the unequal social structure between these actors. This research aimed to analyze social structure in the inland waters of South Sumatra in the practice of the Lebak Lebung and River Auction (L3S) in OKI District. To achieve this goal, a constructivist paradigm with qualitative research methods was employed, and the sample comprised 39 informants selected as subjects. The data analysis was conducted in three distinct stages, namely data reduction, presentation, and drawing conclusions. The results showed that the regulation of open access for all parties in the local government regime after 1982 created an institutionalized social relations structure where the government, investors, traders, middlemen, and non-fishing actors dominated compared to the fishermen. The participants in this social landscape strived to accumulate capital to enhance their competitiveness within the L3S domain. A patronage system was implemented with middlemen assuming the role of patron and the fishermen acting as their clients. The current institutional social structure has created an unfair distribution of resource benefits for fishing workers. The novelty theories were found in the working relations of the inland waters community of South Sumatra, namely stratified distribution of rights, dual status, multi-stage patronage, and the positive function of patronage for chief fisherman. Further research should be conducted to research policy revitalization and develop strategic inland water management models.
Highlight Research
The author mentioned 3 highlights from their results research:

Auction system in inland waters in South Sumatra presents an unfair distribution for fishermen.
Structure of the working relationship formed is an asymmetric patron-client relationship but with novel theories such as the stratified distribution of rights model, dual status, multi-stage patronage, and the positive function of patronage.
An imbalance in local access to auction objects due to their weak ability to accumulate capital.
Effect of M-CSF on the expression of endothelial progenitor cell markers in blood mononuclear cell culture in coronary heart disease
Authors: Chumakova S. P. , Urazova O. I. , Shipulin V. M. , Gladkovskaya M. V. , Andreev S. L. , Nevskaya K. V. , Zima A. P. , Nikulina E. L.
Published: January 2024

Aim. To evaluate the nature of changes in the expression of markers of endothelial progenitor cells (VEGFR2, CD34, CD14) and endothelial cells (CD146) in association with the expression of the leukocyte common antigen CD45 in the culture of blood mononuclear cells in the presence of M-CSF in patients with coronary heart disease (CHD) and healthy donors.

Materials and methods. The study included 12 patients with CHD with class III–V angina pectoris and 10 healthy donors, from whom 30 ml of venous blood was taken on an empty stomach in the morning and stabilized with heparin. Blood mononuclear cells were isolated by Ficoll density gradient centrifugation (1.077 g / cm3) and subject to immunomagnetic separation using CD14-MicroBeads and CD34-MicroBead Kit (Miltenyi Biotec B.V. & Co. KG, Germany). The resulting CD14+ and CD34+ culture of mononuclear cells was incubated for 6 days in a complete nutrient medium with and without M-CSF 50 ng / ml (Cloud-Clone Corp., USA) with complete replacement of the medium and repeated application of M-CSF on day 3. After 6 days, the proportions of CD45+, CD14+, CD34+, VEGFR2+, and CD146+ cells in the culture were assessed by flow cytometry using CD14-FITC, CD34-PE, VEGFR2-Alexa Fluor 647; CD45-FITC and CD146-PerCP antibodies (BD Biosciences, USA).

Results. It was shown that in healthy donors, the proportion of CD146+ cells in the co-culture of blood mononuclear cells with M-CSF exceeded their number in the sample without it, with comparable expression rates of CD45, CD14, and VEGFR2 markers between the control and stimulated cultures. In CHD patients, the number of CD146+ and VEGFR2+ cells did not change when M-CSF was added to the mononuclear cell culture; however, the proportion of CD14+ cells increased and the proportion of CD45+ cells decreased compared to the control sample. The number of CD34+ cells was comparable both between control and stimulated samples, and between the groups of examined individuals. At the same time, in patients with CHD, an increased proportion of VEGFR2+ cells was found in the control and stimulated samples compared to healthy individuals, while an increased proportion of CD14+ cells was detected only in the stimulated culture.

Conclusion. The development of CHD disrupts the response of blood mononuclear cells to the effect of M-CSF, increasing the number of CD14+ and reducing the proportion of CD45+ cells in the culture in the absence of stimulating effects on the expression of endothelial cell marker CD146. At the same time, M-CSF does not affect the expression of CD34 and VEGFR2 in endothelial progenitor cells both in patients with CHD and in healthy individuals.
Notch signaling pathway in the development of imbalanced immune responses in patients with disseminated pulmonary tuberculosis
Authors: Sanina A. E. , Serebryakova V. A. , Urazova O. I. , Gadzhiev A. A.
Published: January 2024

Aim. To determine the role of the Notch signaling pathway in the regulation of Th1 / Th2 lymphocyte balance in patients with disseminated drug-sensitive (DS) and drug-resistant (DR) pulmonary tuberculosis (PT).

Materials and methods. Mononuclear leukocytes were isolated from the venous blood of 13 patients with disseminated PT by density gradient centrifugation. The cells were cultured for 72 h in the complete cell culture medium at 5% CO2 and 37 °C. Preliminarily, CFP10 and ESAT6 mycobacterial antigens or γ-secretase inhibitor DAPT (5 μM / l; 10 μM / l) together with CFP10 and ESAT6 antigens were added to the culture medium. Immunophenotyping of Th1 and Th2 lymphocytes was performed by multicolor flow cytometry by determining the expression of CD4 receptor and intracellular transcription factors T-bet and GATA-3.

Results. In patients with disseminated DS and DR PT, an increase in the number of Th1 and Th2 lymphocytes was found in intact cultures. Stimulation of cells with mycobacterial antigens CFP10 and ESAT6 resulted in an increase in the number of CD4+T-bet+ and CD4+GATA-3+ cells in all comparison groups. Addition of CFP10 and ESAT6 antigens and DAPT (10 μM / l) to the incubation medium was accompanied by a decrease in the number of Th2 lymphocytes in PT patients in both groups. A rise in the number of Th1 cells was registered only in patients with DS PT. Suppression of the Notch signaling pathway with the γ-secretase inhibitor DAPT (10 μM / l) resulted in an increase in the Th1 / Th2 lymphocyte balance in both DS and DR variants of the disease.

Conclusion. The Notch signaling pathway has a modulating effect on the differentiation of the key lymphocyte populations that determine the balance between cell-mediated and humoral immune responses to PT. Suppression of the Notch signaling cascade by the γ-secretase inhibitor DAPT (10 μM / l) in vitro promotes an increase in the Th1 / Th2 ratio in patients with disseminated DS and DR PT. The positive regulatory effect on the Th1 / Th2 lymphocyte balance allows to consider the Notch signaling pathway as a promising potential target in the development of new approaches to the pathogen-specific therapy for PT.
Did Inequalities in Mothers’ and Children’s Health and Well-Being in Japan Increase Through the Pandemic? Evidence From Nationwide Surveys and Routinely Collected Data
Authors: Takeuchi Hajime , Satoh Yoichi , Raman Shanti , Spencer Nick
Published: January 2024

Marginalised families faced significant challenges during the COVID-19 pandemic. This study explores inequalities in Japanese mothers’ and children’s health and wellbeing and family economic stability before and during the pandemic. Data sources were: nationwide surveys in 2019 and 2021 of families with children using medical institutions across Japan; infant mortality and adolescent suicide rates between 2018 and 2021 from publicly available sources. Outcomes by poor and non-poor families were compared for 2019 and 2021 using simple descriptive statistics. Poor mothers' part-time working increased from 41% to 61% and regular employment was reduced by two-thirds. Well-being of poor mothers worsened from 39% to 55%. Employment opportunities and wellbeing did not change for non-poor mothers. School subsidies among poor families increased from 23% to 55%. The infant mortality rate (IMR) among unemployed families increased significantly from 12.9/1,000 to 18.2/1,000 between 2018 and 2021 compared with a decreasing overall IMR from 1.9/1000 to 1.7/1000. Suicide rates in 10-19 year olds increased over the same period although no socio-economic indicators were available. Inequalities in mothers’ and children’s health and well-being indicators and family economics increased between 2019 to 2021 in Japan. This study cannot attribute cause but suggests a possible role of the pandemic.