bluuebunny/crossref_metadata_2025 huggingface dataset:
Dissecting Papaya Leaf Curl Disease (PLCD) Complex and Assessing its Potential for siRNA Based Targeting
Authors: Verma Saurabh , Saxena Sangeeta
Published: December 2017

Carica papaya L. (papaya) production is severely affected by leaf curl and related disease symptoms caused by various species of begomoviruses making it a complex disease. Papaya leaf curl disease (PLCD) complex has broad host range and high genetic variability, therefore, the study was conducted to dissect the genetic complexity of PLCD. Begomoviruses infect various host crops and weeds associated with cultivation of papaya. Intermixing among their genomes and mutational forces drive molecular variability in the disease complex, which enables them to expand their host range. This molecular variability is important determinant when RNA interference based strategy is applied against these viruses. In this study, we have observed that the broad host range of PLCD complex viral components is due to high frequency of recombination events that took place at different time scales. The rise of recombinants led to host variability resulting in similar symptomatic infection over new crops and weeds in nearby fields. Therefore, we have taken into account molecular variability and recombination regions of the viral genome as the targets for providing resistance against these viruses, thus, preventing serious implications of similar diseases spreading over to new hosts.
In vitro Propagation of Saprophytic Moss Splachnum sphaericum Hedw.
Authors: Sahu Vinay , Rawat K. K. , Srivastava Ankita , Asthana A. K.
Published: December 2017

In vitro propagation of Splachnum sphaericum Hedw. has been carried out to study its growth pattern and morphogenetic attributes. Plants of this species were freshly collected from Se La Pass, Tawang, Arunachal Pradesh. Axenic culture of the species has been established using spores as explants. Half Knop's macronutrients, Half Knop's + Vitamins, Hoagland and Murashige and Skoog media were used for culture. Half Knop's macronutrients medium was found as most suitable for the growth of plants under controlled laboratory condition and after 50 days a well grown dense population of gametophores has been achieved. Observations made on morphogenesis of protonema and gametophyte development in different media are provided.
PERSISTENCIA ACADÉMICA EN UN PROGRAMA DE NIVELACIÓN UNIVERSITARIO VENEZOLANO: CASO UNIVERSIDAD SIMÓN BOLÍVAR
Authors: Arias-Gómez Diana , Durán-Aponte Emilse
Published: December 2017

La investigación tuvo como objetivo determinar en qué medida factores previos al ingreso universitario, factores motivacionales y experiencias institucionales explican la persistencia académica de los estudiantes del Ciclo de Iniciación Universitaria (CIU) de la Universidad Simón Bolívar-Sede del Litoral. Se planteó un diseño cuantitativo de tipo explicativo, con un diseño no experimental, transeccional de relación causal retrospectiva. La muestra estuvo conformada por 101 estudiantes (50.5% mujeres) con una edad promedio de 17.90 años (DE= 2.37). Se encontró una relación significativa entre algunas variables que explican la persistencia académica, las cuales fueron: (a) tener menor orientación a las metas académicas, (b) mayor puntaje en patrón desadaptativo, (c) mayor puntaje en la percepción de evaluación del docente de matemáticas y (c) mayor puntaje en el rendimiento final. Este conjunto de variables explica el 56.4% de la persistencia académica en el programa CIU para la muestra de estudio. A partir de los resultados se plantea una posible explicación a la persistencia académica y se analiza la importancia de contrastar los hallazgos con nuevas investigaciones en distintos escenarios académicos.
FOREIGN LANGUAGE TRAINING IN TRANSLATION AND INTERPRETING DEGREES IN SPAIN: A STUDY OF TEXTUAL FACTORS
Authors: Cruz García Laura
Published: December 2017

Foreign language teaching and learning has received a considerable amount of scholarly attention across different stages of education, particularly in the case of English. Apart from language training in general contexts, language for special purposes also constitutes a prolific field of study. However, less research has been conducted on the foreign-language training needs of trainee translators and interpreters and the corresponding teaching methodologies. In order to gain insight into actual teaching practices in this area in Spanish universities, we have studied the methodological approaches used in the classroom by 58 foreign language lecturers at 13 Translation and Interpreting Faculties in Spain, through a research project of Universidad de Las Palmas de Gran Canaria (Spain). Information was compiled from the responses to an ad hoc questionnaire created for this purpose, sent out by email and filled out on a voluntary basis. This article describes the uses made of texts in foreign language classes, to which end we will focus on the responses to one of the questions posed in the questionnaire. One of the key findings of the study is the preponderance of lexical, semantic, morphological and syntactic features, potentially implying teaching methodologies akin to those used in other education settings.
EDITORIAL: Formación de traductores e intérpretes. Avanzando en el enfoque por competencia
Authors: Galán-Mañas Anabel
Published: December 2017

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Local do crime: a preservação e o isolamento e seus reflexos na persecução criminal
Authors: Garcia Tiago Mikael , Régis Jonathan Cardoso
Published: December 2017

O presente estudo baseia-se na definição dos tópicos de maneira objetiva. A conceituação dos tópicos parte da premissa majoritária da doutrina. A importância e necessidade do isolamento e a preservação do local do crime, a classificação dos cenários do local do crime, bem como os aspectos relacionados ao dimensionamento das ações pelos agentes de segurança pública, por óbvio, os profissionais que primeiro se deparam com a cena do local do crime, é o exemplo maior do estudo. O trabalho demonstra a essencialidade das ações eficazes de isolamento e preservação do local do crime e os respectivos reflexos, positivos quando realizados de maneira eficiente, trazendo condições aceitáveis para que os peritos criminais realizem seu levantamento de dados, assim como também negativas, quando da ocorrência de falha nesse processo inicial, uma vez que características importantes da cena do crime se perdem, dificultando a perícia criminal e refletindo em prejuízo na persecução criminal como um todo.
O mal ronda a terra: um tratado sobre as insatisfações do presente - por Tony Judt
Authors: Barros Deolindo de
Published: December 2017

Tony Judt (1948-2010), nascido na Inglaterra e radicado nos Estados Unidos aonde viera falecer em 2010 com sessenta e dois anos, fez uma carreira brilhante e deixou trabalhos de grande envergadura e reconhecimento. Autor/editor de pelo menos 12 (doze) livros, entre eles “Um tratado sobre os nossos atuais descontentamentos”, “Refl exões sobre um século esquecido: 1901- 2000”, “Passado imperfeito”, “Pós-guerra: uma história da Europa desde 1945” etc., lecionou em diversas e destacadas universidades (Cambridge, Oxford, Berkeley e New York University), e em 1995 criou o Remarque Institute (destinado ao estudo da Europa), onde também foi professor e diretor. Igualmente contribuiu amiúde para jornais e revistas (New York Times, New Republic, New York Review of Books e Times Literary Supplement). Ganhou prêmio (Hannah Arendt, em 2007) e o seu livro (Pós-Guerra) também foi distinguido (prêmio de livros Arthur Ross, do Council on Foreign Relations).
Globalização e as ciências sociais anotações sobre os desafios apresentados pela ascensão dos países Brics
Authors: Dwyer Tom
Published: December 2017

A globalização e as transformações do papel do Brasil no mundo desafiam a sociologia brasileira. Novas questões e atores emergem, e novos temas de pesquisa e ensino se impõem de tal forma que países que antes pareciam irrelevantes ao desenvolvimento brasileiro, com destaque para a China, desafiam nossa imaginação sociológica. É preciso compreender as relações se constroem com nossos parceiros dos BRICS e, na medida em que o conhecemos melhor, também aprender com eles.
A criminalização dos movimentos sociais ante a instalação de uma hidrelétrica no Rio Uruguai (Brasil): uma discussão entre o legal e o legítimo
Authors: Rocha Humberto José da
Published: December 2017

As obras de grande escala são propostas por empresas públicas e privadas através do argumento da utilidade pública e de premissas legais. As populações dos locais onde essas são instaladas se organizam em movimentos sociais que reivindicam a legitimidade de seus direitos. Nessa relação conflitiva, analisamos como a criminalização dos movimentos sociais tende a suplantar o binômio legal/legítimo estabelecendo uma assimetria nas relações de poder em favor dos proponentes dessas obras. A fundamentação teórica dialoga com a pesquisa empírica sobre o caso da instalação de uma hidrelétrica na bacia do Uruguai, no Sul do Brasil.
“O sol da liberdade pura aqui reluz contínuo”: a construção da imprensa lusófona na Inglaterra (1808-1822)
Authors: Munaro Luís Francisco
Published: December 2017

O estudo da imprensa periódica luso-brasileira na cidade de Londres entre 1808 e 1822 revela a necessidade sentida pelos elementos luso-brasileiros de instaurarem um dizer-suporte para significar o Reino Português diante do público inglês. O confronto com os jornais ingleses permitiu a solidificação e mesmo a definição de linhas profissionais para o funcionamento da imprensa em Portugal e Brasil. Além disso, forneceu dados importantes para pensar o papel dos intelectuais exilados para o fomento de uma esfera pública literária em língua portuguesa cujas bases de sustentação estavam protegidas pela constitucionalidade britânica.
A educação escolar e a formação humana em tempos de neoliberalismo: reflexões sobre a formação do professor
Authors: Coimbra Leonardo José Pinho , Sousa Ana Paula Ribeiro de
Published: December 2017

Analisa-se nesse ensaio a formação humana e, mais especificamente, a formação dos professores no contexto da sociedade capitalista neoliberal. Se a apropriação dos bens materiais e culturais é condição para o completo desenvolvimento humano, observa-se que o processo, cada vez mais intenso, de apropriação desses bens por parte de uma pequena parcela da população, como grave obstáculo para o processo de desenvolvimento e humanização dos homens. Nesse sentido, a análise sobre a formação dos profissionais da educação, os responsáveis pela formação das demais categorias de trabalhadores, é exemplar. O tecnicismo pedagógico e as políticas atuais para formação de professores no Brasil trouxeram uma série de novos desafios que precisam ser enfrentados se quisermos construir uma educação de qualidade socialmente referenciada.
Rito escolar – perspectiva histórico-pedagógica
Authors: Magalhães Justino
Published: December 2017

Há um rito no educacional escolar, que a escola comporta e a que dá sequência e significado. O currículo é cognição e passagem. O texto escolar é actualizado e ajustado. O ofício escolar é o de leitor-escrevente e o meta-percurso é o de uma mente letrada, mas é sobretudo o sociocultural educativo que confere substância e reificação ao rito. Neste texto apresentarei uma genealogia e uma reiteração do rito escolar, aplicado à criança e aplicado ao percurso do escolar. Procurarei também fundamentar como esse rito que é inerente à formação da pessoa humana integra a instituição educativa e o educacional escolar.
Análise das bases filosóficas dos pressupostos teóricos presentes nas propostas do movimento “por uma educação do campo”
Authors: Neto Luiz Bezerra , Luna Junior Cesar
Published: December 2017

Este artigo busca analisar as Bases Filosóficas dos pressupostos teóricos presentes nas propostas do movimento “Por uma Educação do Campo”. Este movimento liderado pelo MST, em defesa de uma educação do campo serviu principalmente para denunciar as condições a que as escolas da zona rural estavam sujeitas, até aquele momento, segunda metade da década de 1990. Neste artigo partimos do pressuposto de que esse movimento foi constituído em torno de algumas bases teórico-filosóficas, que passamos a analisar. Percebemos que há nelas um ecletismo teórico-metodológico divergente das intenções com as quais os mesmos são indicados, ou seja, há um distanciamento dos objetivos proclamados com as bases teóricas da realidade objetiva da ação prática. O texto apresentado, deriva de pesquisas em que os autores se propuseram a discutir a seguinte questão: Existem fundamentos teórico-filosóficos que preencham satisfatoriamente a lacuna da Educação do Campo? Para tentar responder esta questão buscar-se-á uma identidade teórico-filosófica genuína, da qual sabemos ser um desafio ousado, pois a falta de consenso entre as bases dos principais movimentos sociais que lideram o programa “Por uma Educação do Campo” constitui uma diafonia, ao nosso ver, por não utilizarem os métodos efetivos como óculos para uma leitura da realidade.
O instituto universitário de educação e os desafios da universitarização no contexto das reformas educacionais em Cabo Verde
Authors: Gomes Janice Raquel Sança , Nascimento Manoel Nelito Matheus Nascimento
Published: December 2017

As discussões apresentadas neste artigo integram a análise da pesquisa intitulada “O Instituto Universitário de Educação de Cabo verde e os desafios da universitarização para a formação de professores” com o objetivo de compreender as repercussões do processo de universitarização na formação de professores cabo-verdianos do Ensino Básico (em sua maioria com uma única formação de nível médio), após a frequência de um curso de complemento de licenciatura no Instituto Universitário de Educação. Neste artigo apresentamos resultados das análises das legislações educacionais juntamente com parte das entrevistas realizadas com alunos que frequentaram cursos de complemento de licenciatura no Instituto Universitário de Educação e professoras/coordenadoras dos respectivos cursos. A pesquisa comprovou a relação direta entre reforma educacional e políticas de formação de professores para o cumprimento da mesma.O Instituto Universitário de Educação, embora não represente o movimento completo de universitarização, apresenta elementos que mostram que esse fenômeno está em pleno desenvolvimento.
Revista Estomatológica Herediana: 27 años después.
Authors: Ronquillo-Herrera Hugo
Published: December 2017

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Musculoskeletal disorders associated to dentists work activities in Brazilian primary health care
Authors: Barbosa De Souza Fábio , Braga Costa Isabelle Ribeiro , Silva Pinto Larissa Lívia , Cabral De Melo Márcia Maria Dantas
Published: December 2017

Objetivos: Verifi car la prevalencia de los trastornos musculoesqueléticos asociados con el trabajo (TMEAT) de los dentistas de la red de atención primaria de salud en Recife, Brasil. Material y Métodos: Se utilizó el Cuestionario nórdico de síntomas musculoesqueléticos con el objetivo de identifi car la presencia de dolor, incomodidad o latencia en diferentes áreas del cuerpo. Resultados: El 97,3% de los entrevistados mencionaron los síntomas musculoesqueléticos asociados con la práctica de la Odontología. El Cuello (56,75%); el puño / manos / dedos (54.06%); los hombros (51.35%) y la región lumbar (48,65%) fueron los lugares más afectados. Al medir la asociación entre TMEAT y las “5” variables extraprofesionales estudiadas, solo la actividad física se asoció con síntomas en la región de puño / manos / dedos (p <0,05). Conclusiones: se observó un alta prevalencia de TMEAT en dentistas de Recife. La práctica de actividad física regular demostró ser un posible factor de protección para las lesiones puño / manos / dedos.
Aceptabilidad y eficacia del midazolam oral en jugo y en gelatina en la sedación consciente de pacientes pre-escolares para su atención estomatológica
Authors: Tapia Akemy , Vilcapoma Henry , Nuñez María
Published: December 2017

Objetivos: Comparar la aceptabilidad y efi cacia del midazolam por vía oral (en gelatina y en jugo) en la sedación consciente de pacientes preescolares para su atención estomatológica. Material y métodos: Se incluyeron 50 niños sanos, no colaboradores, preescolares y con necesidad de atención estomatológica bajo sedación consciente quienes fueron asignados al azar a la preparación de midazolam vía oral (0,5mg/kg): jugo o gelatina. Se registraron la aceptabilidad del paciente, puntuaciones de conducta, signos vitales, efectos adversos y tiempo de recuperación. La medicación aplicada fue cegada al operador y al observador. Resultados: La aceptabilidad del midazolam usando gelatina fue signifi cativamente mayor (88%) que usando jugo (56%) (p<0,05). Las puntuaciones de conducta en cada parámetro (llanto, somnolencia, movimiento y comportamiento general) no difi eren en ambas vías de manera signifi cativa. Los valores de los signos vitales tuvieron parámetros normales para ambos grupos (en cada etapa de la sedación). No se identifi caron reacciones adversas en los grupos de estudio. La recuperación promedio para el grupo sedado con midazolam en jugo fue de 117 minutos y para el grupo sedado con midazolam en gelatina fue de 114,24 minutos. Conclusiones: El midazolam administrado por vía oral en jugo y en gelatina es efi caz en el tratamiento estomatológico bajo sedación consciente en niños no colaboradores en edad preescolar. Se destaca el uso del midazolam administrado en gelatina por la mayor aceptabilidad del paciente.
Calidad de vida relacionada a la salud bucal en escolares de Sayausí, Cuenca Ecuador
Authors: Reinoso-Vintimilla Napoleón , Del Castillo-López Cesar
Published: December 2017

Objetivos: El objetivo del presente estudio fue evaluar la calidad de vida relacionada a la salud bucal en los niños de 11 a 12 años de las escuelas de la parroquia de Sayausí Cuenca Ecuador. Material y métodos: Fue un estudio analítico de corte transversal se evaluaron 359 escolares entre 11 y 12 años de edad, que fue toda la población que cumplió con los criterios de selección, se evaluó la calidad de vida relacionada a la salud bucal CVRSB, mediante la encuesta CHILD- OIDP versión validada en Perú. Los pacientes evaluados dieron su asentimiento y sus padres firmaron el consentimiento informado, de acuerdo a las exigencias del comité institucional de ética de la Universidad Peruana Cayetano Heredia. Resultados: Se encontró  que el 98,9% de escolares tenían algún nivel de impacto en su calidad de vida. Las tres condiciones orales auto percibidas como problema que tuvieron mayor frecuencia fueron la caries dental, dientes con sensibilidad y dientes con dolor, siendo 72%; 50% y 50% respectivamente.
Estimación de la edad de acuerdo al método de Demirjian en niños de 5 a 16 años de la ciudad de Guayaquil, Ecuador
Authors: Aguirre-Rueda Evelyn Jesenia , Del Castillo-López Cesar Eduardo , Orejuela-Ramírez Francisco José , León-Manco Roberto Antonio , Quezada-Márquez Milushka Miroslava
Published: December 2017

Objetivos: Comparar la edad cronológica y edad dental según el método de Demirjian en pacientes de 5 a 16 años que acudieron al Centro Radiológico Dr. Virgilio Aguirre Cadena, Guayaquil-Ecuador durante el período2014-2015. Material y Métodos: Se evaluaron 617 radiografías panorámicas tomadas durante el año 2014-2015, posteriormente se procedió a realizar el cálculo de la edad dental utilizando el método de Demirjian de cada uno de los pacientes. Luego se realizó un análisis comparativo con la edad cronológica tomada de la misma base de datos de las imágenes, para lo cual se utilizó la prueba de Wilcoxon. Resultados: La estimación de la edad dental en relación con la edad cronológica, se observó en el sexo femenino dentro del grupo etario de 7-7,99 y el de 10-10,99, presentó buenos estimadores para determinar la edad cronológica, mostrando valores de p=0,6643 y p=0,1147 respectivamente; en el sexo masculino, el grupo etario de 10-10,99 y 12-12,99 mostró buenos esti- madores para determinar la edad cronológica con valores de p=0,2713 y p=0,6996 respectivamente. El resto de grupos no presentó buenos estimadores para determinar la edad cronológica con valores de p˂0,05. Conclusio- nes: El método de Demirjian no es un buen estimador de la edad ósea en todos los grupos etarios de la población estudiada, puesto que, la mayoría de grupos presentan diferencias entre la edad dental y la edad cronológica.
Nitrato de plata y despigmentación gingival de manchas melánicas: un reporte de caso
Authors: Churata Quispe Jhonatan , Correa Quispilaya Emil , Ríos Villasis Katty
Published: December 2017

La pigmentación melánica es una característica de la encía que podría ser considerada como antiestética; tanto por el profesional como por el paciente. Uno de los tratamientos que ha demostrado mayor efectividad es la des- pigmentación mediante el uso del láser; sin embargo, su alto costo limita el acceso en algunos estratos sociales, por ello, se emplean otros métodos, tales como: la abrasión con fresas diamantadas, la criocirugía y la electro- cirugía. Otra alternativa es el uso del nitrato de plata que actúa produciendo coagulación del epitelio, edema y desnaturalización de proteínas; permitiendo una regeneración óptima del epitelio y logrando una estética gingival adecuada. Se presenta un reporte de caso con el uso de esta técnica y su posterior control por periodos hasta los 18 meses post tratamiento.
A Sequential Algorithm for Signal Segmentation
Authors: Hubert Paulo , Padovese Linilson , Stern Julio
Published: December 2017

The problem of event detection in general noisy signals arises in many applications; usually, either a functional form for the event is available, or a previous annotated sample with instances of the event that can be used to train a classification algorithm. There are situations, however, where neither functional forms nor annotated samples are available; then it is necessary to apply other strategies to separate and characterize events. In this work, we analyze 15 minute-long samples of an acoustic signal, and are interested in separating sections, or segments, of the signal which are likely to contain significative events. For that, we apply a sequential algorithm with the only assumption that an event alters the energy of the signal. The algorithm is entirely based on Bayesian methods.
Ocean Dynamics Observed by the VIIRS Day-Night Band Measurements
Authors: Shi Wei , Wang Menghua
Published: December 2017

Three cases of Day-Night Band (DNB) observations of the Visible Infrared Imaging Radiometer Suite (VIIRS) onboard the Suomi National Polar-orbiting Partnership (SNPP) are explored for applications to assess the ocean environment and monitor ocean dynamics. An approach to use the DNB radiance ratio was developed in order to better continuously assess the ocean diurnal and short-term environmental changes with VIIRS DNB observations. In the La Plata River Estuary, the sediment fronts showed 20–25 km diurnal inshore-offshore movements on March 13, 2017. In the waters off the Argentina coast in the South Atlantic, VIIRS DNB measurements provided continuous observations and monitoring of the algae bloom development and migration between 24–26 March 2016. This algae bloom generally kept the same spatial patterns, but moved nearly 20 km eastward in the three-day period. In the Yangtze River Estuary and Hangzhou Bay region in China’s east coast, VIIRS DNB observations also revealed the complicated coastal dynamic changes between 12–14 April 2017. Even though there are still some challenges and limitations for monitoring the ocean environment with VIIRS DNB observations, this study shows that satellite DNB observations can provide additional data sources for ocean observations, especially observations during the nighttime.
Asymmetric Bimodal Exponential Power Distribution on Real Line
Authors: Çankaya Mehmet Niyazi
Published: December 2017

The asymmetric bimodal exponential power (ABEP) distribution is an extension of the generalized gamma distribution to the real line via adding two parameters which fit the shape of peakedness in bimodality on real line. The special values of peakedness parameters of the distribution are combination of half Laplace and half normal distributions on real line. The distribution has two parameters fitting the height of bimodality, so capacity of bimodality is enhanced by using these parameters. Adding a skewness parameter is considered to model asymmetry in data. The location-scale form of this distribution is proposed. The Fisher information matrix of these parameters in ABEP is obtained explicitly. Properties of ABEP are examined. Real data examples are given to illustrate the modelling capacity of ABEP. The replicated artificial data from maximum likelihood estimates of parameters of ABEP and distributions having an algorithm for artificial data generation procedure are provided to test the similarity with real data.
Characterization of Different Cable Ferrite Materials to Reduce the Electromagnetic Noise in the 2–150 kHz Frequency Range
Authors: Suarez Adrian , Victoria Jorge , Alcarria Antonio , Torres Jose , Martinez Pedro A. , Martos Julio , Soret Jesús , Garcia-Olcina Raimundo , Muetsch Steffen
Published: December 2017

The gap of standardization for conducted and field coupled electromagnetic interferences (EMI) in the 2–150 kHz frequency range can lead to Electromagnetic Compatibility (EMC) problems. This is caused by power systems such as PWM controlled rectifiers, photovoltaic inverters or charging battery units in electric vehicles. This is a very important frequency spectral due to interferences generate in a wide range of dives and, specifically, communication problems in the new technologies and devices incorporated to the traditional grid to convert it into Smart Grid. Consequently, it is necessary to provide new solutions to attenuate this kind of interferences, which involve finding new materials able to filter the electromagnetic noise. This contribution is focused on characterizing the performance of different cable ferrite compositions in order to determine the effectiveness of most common materials such as MnZn and NiZn and a new range based on nanocrystalline solutions. This analysis procedure is carried out through two methods: theoretical method by determining the insertion loss through measuring impedance parameter and proposing a new empirical technique based on measuring directly the insertion loss parameter. Therefore, the main aim of this characterization process is to determine the performance of these cable ferrites to reduce the interferences in this controversial frequency range. From the results obtained, it is possible to deduce that nanocrystalline cable ferrites provide the best performance to filter the electromagnetic noise in the 2-150 kHz frequency range.
The Integrative Method Based on Module-Network for Identifying Driver Genes in Cancer Subtypes
Authors: Lu Xinguo , Li Xing , Qian Xin , Miao Qiumai , Peng Shaoliang
Published: December 2017

With advances in next-generation sequencing(NGS) technologies, large number of multiple types of high-throughput genomics data are available. A great challenge in exploring cancer mechanism is to identify the driver genes from the mutation genes by analyzing and integrating multi-types genomics data. Breast cancer is known as a heterogeneous disease. The identification of subtype-specific driver genes is critical to guide the diagnosis, assessment of prognosis and treatment of breast cancer. We developed an integrated frame based on gene expression profilings and copy number variation(CNV) data to identify breast cancer subtype-specific driver genes. In this frame, we employed statistical machine-learning method to select gene subsets and utilized an module-network analysis method to identify potential candidate driver genes. The final subtype-specific driver genes were acquired by paired-wise comparison in subtypes. To validate specificity of the driver genes, the gene expression data of these genes were applied to classify the patient samples with 10-fold cross validation and the enrichment analysis were also conducted on the identified driver genes. The experimental results show that the proposed integrative method can identify the potential driver genes and the classifier with these genes acquired better performance than with genes identified by other methods.
Analyze PFG Anomalous Diffusion via Real Space and Phase Space Approaches
Authors: Lin Guoxing
Published: December 2017

Pulsed-field gradient (PFG) diffusion experiments can be used to measure anomalous diffusion in many polymer or biological systems. However, it is still complicated to analyze PFG anomalous diffusion, particularly the finite gradient pulse width (FGPW) effect. In practical applications, the FGPW effect may not be neglected such as in clinical diffusion magnetic resonance imaging (MRI). Here, two significantly different methods are proposed to analyze PFG anomalous diffusion: the effective phase shift diffusion equation (EPSDE) method and an observing the signal intensity at the origin method. The EPSDE method describes the phase evolution in virtual phase space, while the method to observe the signal intensity at the origin describes the magnetization evolution in real space. However, these two approaches give the same general PFG signal attenuation including FGPW effect, which can be numerically evaluated by a direct integration method. The direct integration method is fast and without overflow. It is a convenient numerical evaluation method for Mittag-Leffler function type PFG signal attenuation. The methods here provide a clear view of spin evolution under field gradient, and their results will help the analysis of PFG anomalous diffusion.
Food Insecurity in Homeless Families in the Paris Region (France): Results from the ENFAMS Survey
Authors: Martin-Fernandez Judith , Lioret Sandrine , Vuillermoz Cécile , Chauvin Pierre , Vandentorren Stéphanie
Published: December 2017

The number of families sheltered in the Paris region (France) increased by a factor of 5 between 1999 and 2009. In 2013, a survey was performed on homeless families in order to characterize their living conditions, their health needs and the developmental problems in children. This random survey was conducted in 17 languages among homeless families sheltered in emergency centers for asylum-seekers, emergency housing centers, social rehabilitation centers and social hotels in the Paris region. The situation was particularly worrying regarding their food security. Indeed, only 14.0% of people were with food security, whereas 43.3% were with low food security and 9.8% very low food security (a situation where children are also affected). Stratified multivariate robust Poisson models showed that some characteristics can lead homeless families to be at higher risk of food insecurity and/or at higher risk of falling into very low food security, such as residential instability, single parenthood, having more than 3 children, depressive symptoms, housing in social hostels, difficult access to cheap or free food locally. These harmful situations are intolerable in such a wealthy region as the Paris region. They argue for a better detection of these families, a closer social follow-up and an increase in food aid.
Probing Quantum Gravity Through Strong Gravitational Lensing
Authors: Marongwe Stuart
Published: December 2017

We report the use of Einstein rings to reveal the quantized and dynamical states of space-time in a region of impressed gravitational field as predicted by the Nexus Paradigm of quantum gravity. This in turn reveals the orbital speeds of objects found therein and the radius of curvature of the quantized space-time. Similarities between the Nexus graviton and the singular isothermal sphere (SIS) in the Cold Dark Matter (CDM) paradigm are highlighted. However unlike the singular isothermal sphere, the Nexus graviton does not contain singularities or divergent integrals. This solves the core cusp problem. In this work, data from a sample of fifteen Einstein rings published on the Cfa-Arizona Space Telescope Lens Survey (CASTLES) website is used to probe the quantized properties of space-time.
Recent Advances of Malaria Parasites Detection Systems Based on Mathematical Morphology
Authors: Loddo Andrea , Di Ruberto Cecilia , Kocher Michel
Published: December 2017

This paper investigates existing mathematical morphology based techniques applied for performing malaria parasites detection and identification in both Giemsa and Leishman stained blood smears images. Malaria is an epidemic health disease and a rapid, accurate diagnosis is necessary for proper intervention. Generally, pathologists visually examine blood stained slides for malaria diagnosis; this kind of visual inspection is subjective, errorprone and time consuming. In order to cope with such issues, computer-aided methods have been increasingly evolved for abnormal erythrocyte and/or parasites detection, segmentation and semi/fully automated classification. The aim of this paper is to present a review of recent mathematical morphology based methods for malaria parasite detection.
Prevalence of Mental Disorders and Addictions among the Homeless Population in the Greater Paris Area, France
Authors: Laporte Anne , Vandentorren Stéphanie , Détrez Marc-Antoine , Douay Caroline , Le Strat Yann , Le Mener Erwan , Chauvin Pierre
Published: December 2017

The Samenta study was conducted in 2009 in the Greater Paris area to estimate the prevalence of psychiatric disorders among the homeless. A cross-sectional survey was performed with a three-stage random sample of homeless people (n = 859), including users of day services, emergency shelters, hot meal distribution, long-term rehabilitation centres and social hotels. Information was collected by a lay interviewer, using the Mini International Neuropsychiatric Interview, and completed by a psychologist through an open clinical interview. In the end, a psychiatrist assessed the psychiatric diagnosis according to the ICD10. One third of the homeless in the Paris area had at least one severe psychiatric disorder: psychotic disorders (13%), anxiety disorders (12%) or severe mood disorders (7%). One in five was alcohol dependent and 18% were drug users. Homeless women had significantly higher prevalence of anxiety disorders and depression and men were more likely to suffer from psychotic disorders. Homeless people of French origin were at higher risk of SPD, as well as people who experienced various adverse life events before the age of 18 (running away, sexual violence, parental disputes, and/or addictions) and those who experienced homelessness for the first time before the age of 26. The prevalence rates of main psychiatric disorders within the homeless population of our study are consistent with those reported in other Western cities. Our results advocate for an improvement in detection, housing and care of psychiatric homeless.
Bio-Inspired Optimal Control Framework to Generate Walking Motions for the Humanoid Robot iCub Using Whole Body Models
Authors: Hu Yue , Mombaur Katja
Published: December 2017

Bipedal locomotion remains one of the major open challenges of humanoid robotics. The common approaches are based on simple reduced model dynamics to generate walking trajectories, often neglecting the whole-body dynamics of the robots. As motions in nature are often considered as optimal with respect to certain criteria, in this work we present an optimal control based approach that allows us to generate optimized walking motions using a precise whole-body dynamic model of the robot, in contrast with the common approaches. The optimal control problem is formulated to minimize a set of desired objective functions with respect to physical constraints of the robot and contact constraints of the walking phases. We apply the method with combinations of different objective criteria to the model of a reduced version of the iCub humanoid robot of 15 internal DOF. The obtained trajectories are executed on the real robot and we carry out a discussion on the differences between the outcomes of this approach with the classic approaches.
On Generalized k-Fractional Derivative Operator
Authors: Rahman Gauhar , Nisar Kottakkaran Sooppy , Mubeen Shahid
Published: December 2017

The main objective of this paper is to introduce k-fractional derivative operator by using the definition of k-beta function. We establish some results related to the newly defined fractional operator such as Mellin transform and relations to k-hypergeometric and k-Appell's functions. Also, we investigate the k-fractional derivative of k-Mittag-Leffler and Wright hypergeometric functions.
Effects of Climate Change on Grassland Biodiversity and Productivity: The Need for a Diversity of Models
Authors: van Oijen Marcel , Bellocchi Gianni , Höglind Mats
Published: December 2017

There is increasing evidence that the impact of climate change on the productivity of grasslands will at least partly depend on their biodiversity. A high level of biodiversity may confer stability to grassland ecosystems against environmental change, but there are also direct effects of biodiversity on the quantity and quality of grassland productivity. To explain the manifold interactions, and to predict future climatic responses, models may be used. However, models designed for studying the interaction between biodiversity and productivity tend to be structurally different from models for studying the effects of climatic impacts. Here we review the literature on the impacts of climate change on biodiversity and productivity of grasslands. We first discuss the availability of data for model development. Then we analyse strengths and weaknesses of three types of model: ecological, process-based and integrated. We discuss the merits of this model diversity and the scope for merging different model types.
Climate Policy Implications of Nonlinear Decline of Arctic Land Permafrost and Sea Ice
Authors: Yumashev Dmitry , Hope Chris , Schaefer Kevin , Riemann-Campe Kathrin , Iglesias-Suarez Fernando , Jafarov Elchin , Whiteman Gail , Young Paul
Published: December 2017

Arctic feedbacks will accelerate climate change and could jeopardise mitigation efforts. The permafrost carbon feedback releases carbon to the atmosphere from thawing permafrost and the sea ice albedo feedback increases solar absorption in the Arctic Ocean. A constant positive albedo feedback and zero permafrost feedback have been used in nearly all climate policy studies to date, while observations and models show that the permafrost feedback is significant and that both feedbacks are nonlinear. Using novel dynamic emulators in the integrated assessment model PAGE-ICE, we investigate nonlinear interactions of the two feedbacks with the climate and economy under a range of climate scenarios consistent with the Paris Agreement. The permafrost feedback interacts with the land and ocean carbon uptake processes, and the albedo feedback evolves through a sequence of nonlinear transitions associated with the loss of Arctic sea ice in different months of the year. The US’s withdrawal from the current national pledges could increase the total discounted economic impact of the two Arctic feedbacks until 2300 by $25 trillion, reaching nearly $120 trillion, while meeting the 1.5 °C and 2 °C targets will reduce the impact by an order of magnitude.
A Novel Strategy for Very-Large-Scale Cash-Crop Mapping in the Context of Weather-Related Risk Assessment, Combining Global Satellite Multispectral Datasets, Environmental Constraints, and in-Situ Acquisition of Geospatial Data
Authors: Dell'Acqua Fabio , Iannelli Gianni Cristian , Torres Marco A. , Martina Mario L. V.
Published: December 2017

Cash crops are agricultural crops intended to be sold for profit as opposed to subsistence crops, meant to support the producer, or to support livestock. Since cash crops are intended for future sale, they translate into large financial value when considered on a wide geographical scale, so their production directly involves financial risk. At a national level, extreme weather events including destructive rain or hail, as well as drought, can have a significant impact on the overall economic balance. It is thus important to map such crops in order to set up insurance and mitigation strategies. Using locally generated data -such as municipality-level records of crop seeding- for mapping purposes implies facing a series of issues like data availability, quality, homogeneity etc. We thus opted for a different approach relying on global datasets. Global datasets ensure homogeneity and availability of data, although sometimes at the expense of precision and accuracy. A typical global approach makes use of spaceborne remote sensing, for which different land cover classification strategies are available in literature at different levels of cost and accuracy. We selected the optimal strategy in the perspective of a global processing chain. Thanks to a specifically developed strategy for fusing unsupervised classification results with environmental constraints and other geospatial inputs including ground-based data, we managed to obtain good classification results despite the constraints placed. The overall production process was composed using ``good-enough" algorithms at each step, ensuring that the precision, accuracy, and data-hunger of each algorithm was commensurate to the precision, accuracy, and amount of data available. This paper describes the tailored strategy developed on the occasion as a cooperation among different groups with diverse backgrounds, a strategy which is believed to be profitably reusable in other, similar contexts. The paper presents the problem, the constraints and the adopted solutions; it then summarizes the main findings including that efforts and costs can be saved on the side of Earth Observation data processing when additional ground-based data are available to support the mapping task.
CISTEM Education with Robotic Platform: For Human-Human Synchrony and Human-Machine Synchrony
Authors: Nakada Kazuki , Tsunematsu Miwako , Kihara Takuya , Hattori Takumu , Tokiwa Tatsuji , Fukuda Hiroshi ,   Graduate School of Information Sciences, Hiroshima City University 3-4-1 Ozuka-Higashi, Asa-Minami, Hiroshima 731-3194, Japan,   Graduate School of Biomedical and Health Sciences, Hiroshima University 1-2-3 Kasumi, Minami, Hiroshima 734-8553, Japan,   Faculty of Health and Medical Sciences, Hokuriku University 1-1 Taiyogaoka, Kanazawa 920-1154, Japan
Published: December 2017

In Hiroshima Prefecture, an inter-university collaborative educational project of an interdisciplinary field: Clinical Informatics and Technology (the CIT program) has being implemented. As a part of the CIT program, we have been working on CISTEM (Clinical Information, Science, Technology, Engineering, Mathematics, and Medicine) education to establish a systematic educational curriculum for students (mainly undergraduate students) who will be responsible for medical engineering cooperation/collaboration in the future. In this paper, from the viewpoints of communication and control engineering, we introduce an attempt to enhance students’ problem consciousness and motivation for research and development by facilitating their self-discovery of the design principles commonly required for medical instruments and medical systems through production tasks utilizing robotic platforms. Especially we introduce our case studies focusing on the significance of human-human synchrony and human-machine synchrony towards the realization of symbiosis among humans and machines. We further propose a model case of an CISTEM education customized for undergraduate students who specialize in information, communication and control engineering based on trials conducted in these case studies.
Study on Assist Education of Swing Riding Using a Robot
Authors: Kawada Kazuo ,   Graduate School of Education, Hiroshima University 1-1-1 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8524, Japan, Ito Masahiro
Published: December 2017

This paper describes a framework for “Robo-iku” (education facilitated by robots) at the kindergarten and primary school levels. We believe the concept of Robo-iku can help to give a unified approach to the problem of the avoidance of science and technology learning. It can also provide young children with opportunities to develop various skills, such as cooperative skills and/or skills to help them relate well to others. We detail the practical experience of a “monotsukuri” workshop for primary school children, a workshop on designing and building rescue robots. A working definition of “Robo-iku” is provided. The results of the workshop imply that the concept of Robo-iku needs to be further investigated.
Does Causal Marketing Matter in the Drugstore Business?
Authors: Wang Min-ju , Shieh Meng-Chih , Pan Frank
Published: December 2017

Drugstore business encountered fierce competition with multiple retailers. Other than professional knowledge and legal protections, drugstores needed to win consumer’s trust by creating a favorable image. Based on the theory of planned behavior (TPB), the current research brought the concept of cause-related marketing into the model, and hypothesized that the consumer’s perceived cause moderates the relationship within TPB variables. 262 consumers of drugstores were gathered for testing. Test results confirm the applicability of TPB, of which subjective norm is the strongest predictor, followed by perceived behavior control and attitude. Moderating effects of perceived cause existed in the relationship. Several suggestions to industry and the academic were provided.
THE STATE AND SOCIAL INTERMEDIATION (MEDIATION) IN TRADITIONAL CHINA
Authors: Даньшин Александр , Dan'shin Aleksandr
Published: December 2017

The main aim of the article is to study the relationship of the institutions of social intermediation and state bodies in traditional China in the process of regulation of civil legal disputes. The law instructed judges to deal with property disputes of private individuals in person (i. e. «minor issues»); however, they thought it possible to intervene in a conflict only when all possible ways of mediation had been exhausted. The intention of the plaintiff to apply to the court immediately could be stopped by the judge's decision to transfer the civil case into a criminal one, which would threaten the plaintiff with serious adverse consequences. If the case was considered by the judge, his decisions, as a rule, were based on the Confucian principle of « ren » (humanity) and not law. Guided by this principle, the court could decide in favor of the debtor, even if his guilt was obvious before the creditor. In addition, the main method of punishment of the debtor was furtigation, which could not guarantee the performance of his obligations. In this regard, most Chinese citizens, regardless of their social status, preferred to refrain from applying to court with their civil cases. The most promising variant for them was the institute of social intermediation (mediation), represented by village headmen ( ts’ilao ) and rural police ( t’ipao ), «noble (perfect) men» ( chüntzu ) and representatives of the «scientific order» ( shênshih ), etc. State control over their brokerage activities was carried out through a system of collective responsibility paochia, and the hsiangpao , who was elected by community members and approved by the local judge. Developing ancient folk traditions, the institute of mediation at the legislative level in contemporary China is recognized as an important form of regulation of civil legal relations, existing in the form of national, commercial, administrative and labor intermediation, the main purpose of which, as in ancient times, is social harmony and stability in the country.