bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Suku Bunga, PER, dan PBV Terhadap Harga Saham Perusahaan Sub Sektor Konstruksi Bangunan
Authors: Arbaningrum Rosa , Muslihat Asep
Published: September 2021

The study aims to determine how much influence of interest rate, PER, and PBV have on stock prices. The method used is descriptive verification with a quantitative approaches. Data were analyzed using multiple linear regression analysis. Based on the results of a descriptive analysis of the highest interest rate occurred in 2014-2015 while the lowest interest rate in the 2017. There are 5 building construction sub-sector companies that have PER industry average, while 4 other companies have PER above industry average. Furthermore, there are 4 companies that have the value of PBV below the industry average and 5 companies have PBV above the industry average. Then, there are 5 companies that have a share price above the industry average and 4 companies have the stock price below the industry average. Based on the result of verificative analysis that interest rate variable has no signification effect on stock price, while PER variable has no signification effect on stock price and PBV variable has signification effect on stock price. R square test result show that the interest rate, PER, and PBV has effect of 29,3% against the stock price so that remaining 71,7% is affected by other variables that are not researched.

Keywords: Interest Rate; PER; PBV; Stock Price.
Pengaruh Ukuran Perusahaan, Profitabilitas, Leverage, Dan Kinerja Lingkungan Terhadap Environmental Disclosure
Authors: Maulana Agus , Ruchjana Eva Theresna , Nurdiansyah Dian Hakip
Published: September 2021

The background of this study is intend to identify, analyse, and describe the effect of size company, profitability, leverage, and environmental performance on environmental disclosure. The data on this uses a descriptive verificate research with a quantitative approach. In this study, used researches purposive sampling to determine the samples. This research using the secondary data taken from annual report that is published by companies sample. While in the process of data analysis in this research using SPSS 26 software consisting of classical assumption test (normalitas test, autocorrelation test, heteroskedastisity test and multicolinearity test) double regresilinear analysis, hypotesis test (t statictical test and F statistical test) and coefficient of determination test. The result of reseach is profitability has a negative influence on environmental disclosure. As for the size company, leverage, and environmental performance have no influence on environmental disclosure.

Keywords: Company Size, Profitability, Leverage, Environmental Performance, Environmental Disclosure.
Pengaruh Word Of Mouth Dan Kepercayaan Terhadap Keputusan Pengambilan Kredit Usaha Rakyat (KUR) Bank Bni Unit Jalan Baru Kabupaten Karawang
Authors: Salamah Ismi , Sudrajat Ajat
Published: September 2021

This study aims to determine the description of the variable word of mouth, customer trust, and decision making of people's business credit (KUR) at Bank BRI Unit Jalan Baru, Karawang Regency. In addition, this study aims to determine the effect partially and simultaneously between word of mouth and customer trust on the decision to make people's business credit (KUR) at Bank BRI Unit Jalan Baru, Karawang Regency. The type of data used in this research is quantitative data. This research was conducted on customers of the People's Business Credit (KUR) BRI Bank Unit Jalan Baru, Karawang Regency. The analysis model used in this research is the path analysis model. Based on the results of descriptive analysis, it shows that the word of mouth variable gets an average score of 474 on the agreeing criteria, then the customer trust variable gets an average score of 435.5 in the agreeing criteria, while the people's business credit decision-making variable (KUR) gets an average -The average score of 494.5 is on the agreed criteria. Based on the results of hypothesis testing, it shows that there is a partial and simultaneous influence on word of mouth and customer trust on the decision of making people's business credit (KUR) at Bank BRI Unit Jalan Kabupaten Karawang. 

Keyword : Word of mouth, Costumer Trust, Dicision Making Kredit
Pengaruh DER, CR, DPR, EPS, Inflasi, Dan Pertumbuhan Arus Kas Operasi Terhadap Return Saham Pada Perusahaan Sektor Property, Real Estate dan Konstruksi Bangunan Di BEI
Authors: Wulandari Bayu , Wijaya William , Winata Veronika , Kathy Kathy , Septani Lise
Published: September 2021

The purpose of this research is to carry out analysis regarding the influence of Operating Cash Flow Growth, Inflation, Earning per Share Ratio, Debt to Equity Ratio, and Current Ratio on Stock Returns in building, property, and real estate construction companies. In the implementation of this research, the population used is building construction companies, property, and real estate which are listed on the Indonesia Stock Exchange for the period 2016 to 2019. In this study, the sampling technique is using purposive sampling. The data used are quantitative secondary data. The data analysis method is multiple linear regression. Based on the results of the analysis, it is determined that simultaneously the independent variable Debt Equity Ratio, the independent variable Current Ratio, the independent variable Earning per Share, the independent variable Dividend Payout Ratio, Inflation and Growth in Operating Cash Flow do not provide contribution to the influence of Stock Return. Partially the results of the analysis determine that the independent variable of the Debt Equity Ratio contributes a significant effect on stock returns, meanwhile for the independent variables of Current Ratio, Dividend Payout Ratio, Earning per Share, Inflation and Operating Cash Flow Growth did not contribute significantly to Stock Returns.

Keywords: Debt Equity Ratio, Current Ratio, Dividend Payout Ratio, Earning Per Share, Inflation, Operating Cash Flow Growth and Stock Returns
Pengaruh Transparansi, Kompetensi, Dan Sistem Akuntansi Keuangan Terhadap Akuntabilitas Pengelolaan Keuangan Daerah Dengan Penerapan Sistem Pengendalian Internal Pemerintah Sebagai Variabel Moderasi
Authors: Herlina Ria , Taufik Taufeni , Nasir Azwir
Published: September 2021

This study aims to examine the effect of transparency, competency, financial accounting systems on the accountability of regional financial management with the government's internal control system as a moderating variable with a case study in Indragiri Hulu Regency. The population of this study were all employees in all OPDs in Indragiri Hulu Regency as many as 45 OPDs so that a sample of 180 respondents was obtained from this population using the purposive sampling method. The data analysis method used in this research is the quantitative analysis method with WarpPLS version 6.0 as data processing software. The results show that transparency, competency, and financial accounting systems affect the accountability of regional financial management, the implementation of the government internal control system can moderate the effect of transparency and financial accounting systems on the accountability of regional financial management, and the implementation of the government internal control system cannot moderate the effect of competency on the accountability of regional finance management.

Keywords: Transparency, Competency, Financial Accounting System, The Accountability of Regional Financial Management, Implementation of The Government Internal Control System
Pasar Modal dan Penanaman Modal Asing di Indonesia
Authors: Jamil Poppy Camenia , Hayati Restu
Published: September 2021

The role of the capital market for the economy of a country according to capital market education by PT. There are two functions of the Indonesia Stock Exchange, namely as a means of business funding or as a means for companies to obtain funds from investors (investors) for business development, expansion, additional working capital and others. This study aims to explain the relationship between the capital market and foreign investment in Indonesia. The variables used in this study are the return of the Composite Stock Price Index (IHSG) and Foreign Direct Investment (FDI) from 2003 to 2019. Data analysis techniques use regression analysis to explain the relationship between the capital market and foreign investment in Indonesia. Indonesia. The final results of the achievements in this study are to increase literacy understanding about economic activities, capital markets, investment to contribute to economic growth.

 Keywords: IHSG, FDI, Investment, Capital Market, Stock Index.
Pengaruh Net Profit Margin (NPM) Dan Debt To Assets Rasio (DAR) Terhadap Return Saham
Authors: Noviyanti Lusi , Zarkasyi Moh. Wahyudin
Published: September 2021

This study aims to determine the effect of Net Profit Margin and Debt to Assets Ratio on Stock Return. The sampling method using purposive sampling, obtained a sample of 13 companies. The research data uses secondary data, namely from the financial statements of the food and beverage subsector companies listed on the Indonesia Stock Exchange for the 2014-2018 period eith miltiple linear regression analysis testing with the help of SPSS version 22 using teh normality test, multicollinearity test, heteroscedasticity test, autocorrelation test, t test, f test and the coefficient of determination. The examiner shows that partially NPM has no effect on stock returns and DAR has no effect on stock returns. And simultaneously NPM and DAR have no effect on stock returns.

Keyboards: Net Profit Margin (NPM), Debt to Assets Ratio (DAR), Stock return
Pengaruh Struktur Modal, Profitabilitas, Dan Kebijakan Dividen Terhadap Nilai Perusahaan
Authors: Desniati Nur Eka , Suartini Sri
Published: September 2021

Business competition in indonesia very tight make company to sho the best value of company The purpose of thi research is to analyzing the effect of capital structure, profitability, and Dividend Policy on Firm value. The sample research is a companies listed on the indonesia stock Exchange on period of 2014-2018. The type of data used is secondary data. The sampling technique used purposive sampling method. Analitycal technique used are the multiple regression anaysis with a significance level a=5%. The result of this research indicates that variabel capital structure has a positive and significant effect on firm value. profitability has a positive and significant effect on firm value. Dividend Policy has a positive and significant effect on firm value.simultaneousl capital stucture, profitability, Dividen policy, on Firm value by 78,1% and the rest was influenced by other variables.

Keywords: Capital Structure, Profitability, Dividen policy, Firm value
Pengaruh Bauran Pemasaran Terhadap Keputusan Pembelian Konsumen Produk Kartu Perdana Pascabayar Halo Pada PT. Telkomsel Grapari Makassar
Authors: Safrida Safrida , Musmulyadi Musmulyadi
Published: September 2021

This research was conducted with the aim of: (1) examining and analyzing the effect of the product on consumer purchasing decisions for postpaid hello card products; (2) examining and analyzing the effect of price on consumer purchasing decisions for postpaid starter pack hello; (3) examining and analyzing the effect of promotion on consumer purchasing decisions for postpaid starter pack hello; (4) examining and analyzing the effect of place on consumer purchasing decisions for postpaid starter pack hello; (5) examining and analyzing the four factors that have the most dominant influence on consumer purchasing decisions for postpaid hello card products. This study uses primary data and secondary data. In this study, the sample used was 100 consumers. based on secondary data at the end of 2015 to December 2016. Data was collected through questionnaires and data tabulation was carried out. Methods of data analysis using multiple linear regression analysis and analysis of the coefficient of determination and descriptive analysis with the help of the Statistical Product and Service Solutions (SPSS) program. These results indicate that: (1) the product variable has a positive but insignificant effect on consumer decision making to buy postpaid starter pack hello: (2) the price variable has a positive and significant effect on the decision to buy a postpaid starter pack hello: (3) promotion variable has a significant effect on the decision to buy postpaid starter pack hello: (4) the place variable does not have a positive and significant effect on the decision to buy the postpaid starter card hello: (5) the most dominant variable influencing decision making is the price variable.

Keywords: Product, Price, Place, Promotion, and Purchase Decision
Pengaruh Struktur Kepemilikan Institusional Dan Financial Leverage Terhadap Manajemen Laba
Authors: Ayudia Titania , Hapsari Nesti
Published: September 2021

This study aims to determine whether there is an influence of Institutional Ownership Structure, Debt to Equity Ratio, and Debt to Asset Ratio to the Earnings Management partially or jointly. The method used in this research is descriptive method verification with a quantitative approach sourced from the annual financial statements on manufacturing companies sub sector of food and beverage, and literature studies. The sampling technique uses non probability sampling with purposive sampling technique. The data obtained were analyzed by testing the classic assumption, multiple linear regression analysis and hypothesis testing using t test and f test. This study uses the SPSS version 26 program to process data. The results of this study indicate that, Institutional Ownership Structure does not affect the Earnings Management, Debt to Equity Ratio (DER) have a negative and significant effect the Earnings Management, Debt to Asset Ratio (DAR) have a positive and significant effect the Earnings Management. And simultaneously Institutional Ownership Structure, Debt to Equity Ratio, and Debt to Asset Ratio have a  affect the Earnings Management. 

Keyword : Institutional Ownership Structure, Debt to Equity Ratio (DER), Debt to Asset Ratio (DAR), and Earnings Management.
Pengaruh Current Ratio Dan Debt To Equity Ratio Terhadap Profitabilitas ( ROE)
Authors: Tiani Yosi , Hasanuh Nanu
Published: September 2021

This study aims to prove and analyze the effect of Current Ratio and Debt to Equity Ratio to Return on Equity in basic industrial and chemical sub-sector manufacturing companies listed on the Indonesia Stock Exchange from 2016 to 2018.These are 76 companies listed on the Indonesia Stock Exchange 2016-2018. Of the 76 listed companies, 10 companies were selected using purposive sampling. The data used in this study are secondary data, with how to collect the information needed from idx in the form of financial statements for 2016-2018. The method used to analyze the relationship between independent variables with the dependent variable is multiple regression method, and assumption test. Results of the discussion shows that simultaneously the independent variables: Current Ratio and Debt to Equity Ratio with the F test, jointly affects the Return on Equity. Result partially with the t test, the variable Current Ratio and Debt to Equity Ratio have an effect against Return on Equity.

Keywords : ROE, Debt to Equity Ratio, Current Ratio
Dinamika Hukum Perpajakan Di Indonesia Ditinjau Dari Undang-Undang Nomor 28 Tahun 2009 Tentang Pajak Daerah Dan Distribusi Daerah
Authors: Fudika Moza Dela , Hamzah Rosyidi
Published: September 2021

Changes in tax regulation policies as an implication of regional autonomy in Indonesia starting from Law Number 18 of 1997 concerning Regional Taxes and Regional Levies, then amended by Law Number 34 of 2000 concerning Amendments to Law Number 18 of 1997 concerning Taxes Regions and Regional Retribution. This regulation was later replaced by Law Number 28 of 2009 concerning Regional taxes and Regional Levies. Of the three regulations, legal dynamics occur that lead from decentralized to centralized. The research method in this study uses the normative legal method. From the results of the study, it is found that the dynamics of taxation law in Indonesia in terms of law number 28 of 2009 concerning regional taxes and regional distribution have experienced legal changes in terms of types of taxes, discretionary rate setting, and the nature of determining the type of tax of the law prevailing previously which led to a decentralized to centralized nature as well as a change in tax determination policy from an open list system to a closed list system.

Keyword : legal dynamics, taxation, regional taxes and regional distribution
Study of the influence of interfering ions of heavy metals and various sample preparation on the determination of mercury impurity in protamine sulfate by stripping voltammetry
Authors:   Novosibirsk State Medical University, Kim N.O. , Ivanovskaya E.A. ,   Novosibirsk State Medical University
Published: September 2021

Aim. To determine the content of mercury in protamine sulfate samples with different sample preparation. To study the effect of interfering ions on the content of mercury impurity in protamine sulfate by stripping voltammetry (SV). Materials and methods. We used a solution for injection of protamine sulfate, batches 515091, 514062, 514111; for sample preparation — various options for dilution and precipitation. Dilution was carried out with bidistilled water, and the precipitation of proteins — with sodium tungstate in 2 options. Mercury impurities were determined by the SV method. Results. The mercury content in protamine sulfate samples was 0.000417 ± 0.00140 and 0.000420 ± 0.00152 mg/l when diluted with water 1 : 2 and 1 : 1 respectively and 0.000462 ± 0.00131 and 0.000459 ± 0.00121 when precipitated with tungstate in options 1 and 2 respectively. With the addition of an interfering ion, for example, Cu2+, the content of mercury in the medicinal product was 0.000606 ± 0.00015, 0.000452 ± 0.00013 and 0.0004212 ± 0.00011 mg/l for protamine sulfate batches 514062, 515091 and 514111 respectively, which does not exceed the values determined by the product specification. The addition of Pb2+, Fe2+, Zn2+, Cu2+, and Cd2+ ions also had no effect on the determination of the mercury content in protamine sulfate samples. Conclusion. To determine the mercury impurity in the protamine sulfate, special sample preparation is not required. Ions of Cu2+, Pb2+, Fe2+, Cd2+, Zn2+ do not affect the result of determining the mercury content in protamine sulfate samples by the SV method, which indicates a high selectivity of the method used.
Pharmacoepidemiological analysis of the use of antimicrobial drugs for diseases of the lower respiratory tract in the pulmonary department of a multifield hospital of the Republic of Tajikistan
Authors:   Tajik National University (Dyushambe, Republic of Tajikistan), Saidova M.N. , Pulotzoda I.P. ,   Main Department of the Service of the State Supervision  of Healthcare and Social Protection of the Population in the Sughd Region (Khojend, Republic of Tajikistan), Sanginova N.S. ,   Medical College (Gulistan, Republic of Tajikistan)
Published: September 2021

Aim. Assessment of the use of antimicrobial drugs (AD) in the pulmonary department of a multifield hospital (MH), the Republic of Tajikistan. Materials and methods. A retrospective analysis of medical prescriptions of patients who were treated in the pulmonary department of the Sughd Regional Clinical Hospital (city of Khojend, the Republic of Tajikistan) in 2011–2018 was carried out. The use of AD was evaluated in total, by groups in accordance with the WHO ATC/DDD index: penicillins, cephalosporins, aminoglycosides, fluoroquinolones, tetracyclines, and other antibiotics, as well as separately by international nonproprietary names of drugs. The measurable unit was the number of grams of an active substance, followed by the calculation of the indicators DDD/100 bed-days and percentage of total DDD. Results. Significant changes in the structure of AD used for the initial antibacterial therapy of respiratory tract infections during the study period were revealed. There is a marked tendency to reduce the use of AD of the penicillin family and macrolides, with the transition to monotherapy with cephalosporins of the 3rd generation (ceftriaxone) and partially with fluoroquinolones. Conclusion. Monitoring the use of AD in hospital departments on basis of the ATC/DDD methodology allows to make strategic decisions regarding the tactics of antibacterial therapy, determine the orientation of administrative measures and improve the range of antibacterial agents with the introduction of the modern effective drugs into practice in the future.
New aspects of the etiology and pathogenesis of HIV infection (literature review)
Authors:   Novosibirsk State Medical University, Kapustin D.V. , Ul’yanova Ya.S. ,   City Infectious Clinical Hospital No. 1 (Novosibirsk), Karpovich G.S. ,   Novosibirsk State Medical University, Krasnova E.I. ,   Novosibirsk State Medical University, Kuznetsova V.G. ,   Novosibirsk State Medical University, Izvekova I.Ya. ,   Novosibirsk State Medical University
Published: September 2021

The paper presents the review on current ideas about the etiology and pathogenesis of HIV infection. It highlights the issues of the immune response in this disease, as well as the problems of HIV resistance to modern drugs.
Possibilities of neural networks application in assessing the results of intravascular ultrasound (literature review)
Authors:   Novosibirsk State Medical University, Madonov P.G. , Khidirova L.D. ,   Novosibirsk State Medical University, Kovalev E.A. ,   Novosibirsk State Medical University
Published: September 2021

The review considers the experience of neural networks use in assessing the results of intravascular ultrasound investigation (detection of vulnerable plaques, extraction of the lumen and layers of the vessel wall, prediction of the fractional fl ow reserve).
Pharmacy business and its social responsibility
Authors:   Saint Petersburg State Chemical Pharmaceutical University, Kareva N.N. , Shvetsova V.D. ,   Saint Petersburg State Chemical Pharmaceutical University
Published: September 2021

In the modern world, the corporate social responsibility (CSR) is an important factor that determines the optimal use of resources for the sustainable development of the organization. The CSR is not just the responsibility of an organization to the state, people and other organizations that it encounters in the course of its activities, but the philosophy of a company that takes care of its reputation and competitive advantages in its development, as well as ensuring a decent standard of living for its employees. The pharmaceutical business, including pharmacy, is one of the most important and socially signifi cant branches of the modern economy of the country. However, the problems of social responsibility of pharmaceutical market participants remained outside the scope of interests of domestic scientists. The above highlights the relevance and scientifi c novelty of the study. The aim of the research was to study the social responsibility in the fi eld of pharmacy business. The materials of the study were primary sources of information (questionnaires) and secondary were the offi cial websites of pharmacy chains in Russia.
Granulomatosis as a component of proliferative reactions in the liver and pancreas after partial hepatectomy in the setting of superinvasive opisthorchiasis
Authors:   Tyumen State Medical University, Lazarev S.D. , Uruzbaev R.M. ,   Tyumen State Medical University; Clinical Medical Center “Medical City” (Tyumen), Khadieva E.D. ,   District Clinical Hospital (Khanty-Mansiysk); Khanty-Mansiysk State Medical Academy, Kulikova S.V. ,   Tyumen State Medical University, Kosikina А.V. ,   Tyumen State Medical University, Vikhareva L.V. ,   Tyumen State Medical University, Bychkov V.G. ,   Tyumen State Medical University
Published: September 2021

Introduction. Opisthorchiasis on the territory of Russia has a predominantly superinvasive form, i.e., the disease in hyperendemic foci proceeds with more severe manifestations and structural changes in the parasite’s ecological niche (liver, pancreas). With superinvasive opisthorchiasis (SO) in humans and animals, granulomatous infl ammation with the formation of granulomas is observed. Aimoftheresearch. To reveal the features of the granulomatous process in the liver and pancreas after partial hepatectomy in the setting of superinvasive opisthorchiasis in Syrian hamsters. Materials and methods. Research animals were divided into 2 groups: group 1 (n = 180) — SO modeling by introducing into the stomach of 50 Opisthorchis (O.) felineus metacercariae, superinvasions with 50 O. felineus metacercariae were repeated on the 6, 16th days after the primary infestation; group 2 (n = 86) — modeling of SO according to the same scheme as for group 1, and partial hepatectomy (PHE) (removal of the median lobe of an organ, 17.3–17.7% from its mass) on the 16th day after the last superinvasion. The animals were removed from the experiment on 7, 16th, 23rd, 32nd, 38, 120, 240th day. The study of liver and pancreas preparations was carried out using histological, histochemical, immunohistochemical methods. Results. The types, morphogenesis, course, outcomes of granulomas in the liver and pancreas were revealed. The factors of granuloma formation were the secretome, eggs and metabolites of O. felineus in both experimental groups. Conclusion. Granulomatosis in superinvasive opisthorchiasis, including after PHE, is an emergent state of the parasite-host system due to the accumulation of antigenic material in an amount exceeding the nonequilibrium state in this system. The regenerative process in the group of animals after PHE in the SO setting does not affect granulomatous infl ammation and the formation of granulomas.
Forecasting importance of ultrasound semiotics for the choice of further diagnostic procedures and treatment methods for patients with abdominal abscesses (literature review)
Authors:   Consultative and Diagnostic Outpatient Clinic No. 27 (Novosibirsk), Grechikhina M.V. , Gorbunov N.A. ,   Novosibirsk State Medical University, Dergilev A.P. ,   Novosibirsk State Medical University
Published: September 2021

The purpose of the review is to show that the ultrasound picture at the initial diagnosis can become decisive for the planned examination and treatment of patients with abdominal abscesses. The article analyzes the possibilities of using the ultrasound method, describes its advantages and disadvantages. The key points related to the formation of an ultrasound picture of cavity formations of various etiologies and localization, their difference from pathological cavity formations of a purulent-destructive nature are considered. The main ultrasound signs of abdominal abscesses of various localization, which play a leading role in the choice of further patient management tactics, are determined.
The effect of bee venom and hyperthermia on the lipoperoxidation and antioxidant activity of the blood of tumor-bearing animals
Authors:   Lobachevsky State University of Nizhny Novgorod, Shabalin M.A. , Deryugina A.V. ,   Lobachevsky State University of Nizhny Novgorod, Nazarova V.V. ,   Lobachevsky State University of Nizhny Novgorod, Gracheva E.A. ,   Lobachevsky State University of Nizhny Novgorod, Lizunova A.S. ,   Ryazan State Medical University n.a. academician I.P. Pavlov
Published: September 2021

Introduction. Nowadays, it has been shown that one of the possible ways to increase the effectiveness of the treatment of malignant tumors is the use of combined treatment methods. Aim. To study the intensity of lipid peroxidation (LPO) and the activity of superoxide dismutase (SOD) in hyperthermia against the background of bee venom in the blood of tumor-bearing rats. Materials and methods. The experimental animals were divided into 5 groups: 1st — intact; 2nd — control (tumor-bearing animals (PS-1 tumor strain) with intraperitoneal (IP) administration of saline solution); 3rd, 4th and 5th groups — tumor-bearing animals with IP administration of 0.5 ml of bee venom against the background of hyperthermia 42, 43 and 44°C respectively. The content of diene and triene conjugates, Schiff bases (SB) and SOD activity in the blood of animals was determined. Results. From the 1st day after the end of the experiment, a statistically significant decrease in triene conjugates was recorded in all experimental groups compared to the control group. SB decreased on the 1st–7th day after the end of the experiment with the action of hyperthermia 42°C and bee venom, on the 7th–28th day — with the action of hyperthermia 43°C and bee venom, and on the 28th day — with the action of bee venom and hyperthermia 44°C, which was accompanied by an increase in SOD activity from the 7th day in all experimental groups compared to the control group. Conclusion. Hyperthermia in combination with the action of bee venom causes a decrease in lipid peroxidation products and an increase in antioxidant activity in the blood of tumor-bearing rats. The most effective action, in our opinion, is the use of bee venom against the background of hyperthermia of 43°C, at which a prolonged effect is recorded both with respect to a decrease in the concentration of SB and an increase in the activity of SOD.
Myocardial stress of the left ventricle during occupational vibration
Authors:   Novosibirsk State Medical University, Tretyakov S.V. , Popova A.A. ,   Novosibirsk State Medical University
Published: September 2021

Aim. Study of intramyocardial stress of the left ventricle (LV) in persons exposed to occupational vibration and patients with hand-arm vibration syndrome (HAVS). Materials and methods. We examined 15 individuals exposed to vibration, 44 individuals with grade 1 HAVS, 10 individuals with grade 2. The control group consisted of 20 persons without cardiovascular pathology, who had not been exposed to hazardous occupational factors. The main occupational hazards in persons with HAVS were vibration, noise, physical exertion. Echocardiography was carried out to determine the total volume of LV (Vtotal); the volume of myocardium (Vm); myocardial mass (LVMM); myocardial mass index (LVMMI); systolic intraventricular pressure; the intensity of the functioning of the LV structures; LV circumferential and meridional diastolic and systolic stresses (σcd, σcs and σmd, σms respectively); LV tension in the circumferential and meridional direction during systole and diastole (Tcs, Tcd and Tms, Tmd respectively). Results. In persons exposed to vibration, in comparison with those who have not been exposed to occupational hazards, there is an increase in σmd by 2.5 times (p < 0.05) and σcd by 2.8 times (p < 0.05). The tension increases during systole and diastole both in the circumferential (Tcs by 17.35%, p < 0.05; Tms by 2.74 times, p < 0.05) and in the meridional (Tcd by 14.59%, p < 0.05; Tmd by 2.76 times, p < 0.05) directions. In persons with grade 1 HAVS, there is an increase during diastole σmd by 2.2 times (p < 0.05), σcd by 2.4 times (p < 0.05), and Tmd (p < 0.05) and Tms by 2.5 times (p < 0.05). In patients with grade 2 HAVS, in contrast to those with grade 1 and persons exposed to vibration, there is a change in the working conditions of LV. With the same values of Vtotal, Vm, LVMM and LVMMI, as in the described groups, in patients with grade 2 HAVS, there is a decrease by 12.3% (p < 0.05) in systolic intraventicular pressure against the background of an increase in σmd by 14.7% (p < 0.05), Tmd by 13.6% (p < 0.05), as well as σms by 2.25 times (p < 0.05) and Tcd by 1.97 times (p < 0.05). Conclusion. In the group of persons exposed to vibration and patients with grade 1 HAVS, in contrast to those who are not exposed to occupational hazards, there is an increase in stress and tension, primarily in the circumferential direction during diastole, which indicates the activation of the heterometric type of autoregulation of activity of the heart. In patients with grade 2 HAVS, stress and tension increase in the meridional direction during systole, which indicates the levelling of LV hyperfunction by isotonic type.
Hydropic degeneration of the sensorimotor cortex of white rats in the context of the formation of dark neurons and changes in neuroglial relationships following short-term common carotid arteries occlusion
Authors:   Omsk State Medical University, Gorbunova A.V. , Stepanov S.S. ,   Omsk State Medical University, Akulinin V.A. ,   Omsk State Medical University; Omsk State Agrarian University n.a. P.A. Stolypin, Avdeev D.B. ,   Omsk State Medical University, Shoronova A.Yu. ,   Omsk State Medical University, Makaryeva L.M. ,   Omsk State Medical University, Konev V.P. ,   Omsk State Medical University
Published: September 2021

Introduction. Neurodegenerative processes are key in the development of a number of diseases — strokes, Parkinson’s and Alzheimer’s diseases, epilepsy, and traumatic brain injury. They include primary and secondary structural and functional changes in the nervous tissue, as well as the death of neurons and complete loss of functions. Aim. To study the manifestations of hydropic degeneration and reorganization of glio-cytoarchitectonics during the formation of dark neurons in the sensorimotor cortex (SMC) of the cerebrum of mature white rats in 40 min after the common carotid arteries occlusion (CCAO). Materials and methods. A 40-minute CCAO was simulated in white Wistar rats. The brain was fi xed by perfusion method. Morphometric assessment of manifestations of edema — swelling, cyto- and glio-cyto-architectonics of SMC was performed normally (n = 6, control group), on the 1st (n = 6), 3rd (n = 6) and 7th days (n = 6) after CCAO. The Nissl staining, hematoxylin and eosin, immunohistochemical typing NSE, MAP-2, GFAP and AIF1 were applied. The relative area of edema-swelling zones, the numerical density of normochromic and dark pyramidal neurons, oligodendrocytes (OD), microgliocytes (MG) were determined. Results. The high content (20–50%) of dark neurons after CCAO was accompanied by a 3.3-fold increase in the relative area of edema-swelling zones (r = 0.82, p = 0.01). Specifi c proteins (NSE, MAP-2) of most dark neurons were preserved. The total numerical density of SMC neurons decreased by 26.4% (layer III, p = 0.001) and 18.5% (layer V, p = 0.01) after 7 days of CCAO. The content of astrocytes, MG and OD increased. The peak in the number density of MG was observed in the 1st day, and OD — in the 7th day after acute subtotal ischemia (p ≤ 0.001). The revealed changes were of a diffuse-focal nature. Conclusion. After a 40-minute CCAO, the content of dark neurons in SMC increased and, as a result, signs of hydropic degeneration appeared. Against this background, the number of satellite OD, astrocytes and MG increased. Probably, edema-swelling, active MG and astrocytes previously (on the 1st – 3rd day) sanitate the nerve tissue, ensuring its subsequent (on the 7th day) structural and functional recovery with the participation of OD
EXHIBITING EVERYTHING: A REVIEW ON DAMIEN HIRST’S “REAL” EXHIBITION
Authors: KARAKAŞ TABAK Dilara
Published: September 2021

In the development process of art, it is seen that many different artistic styles follow each other. Each movement has been linked to each other in a chain and the way of expression of the artists has been directly affected by the conditions of the period and the cultural background. Contemporary art is undoubtedly completely different from any movement that comes before it. The sharpest point of the break is that the perception of beauty has changed. As a result of this change, a new type of expression that is often difficult to understand, questioning, related to concepts and contexts has emerged. With the transformative power of contemporary art, every object can gain the ability to represent and become a work of art. In this respect, making iconographic analysis in order to better understand the nature of contemporary art requires evaluating the work together with the conditions of the period. In this study, Damien Hirst's new exhibition named "Fact Paintings and Fact Sculptures" has been examined together with the subject of the works, the explicit or hidden meanings of the objects, the past exhibitions of the artist and the similarities of his works with his past works, and the artistic conditions of the period. As a result of the examination, it is seen that the exhibition clearly reflects Hirst's artistic style.
Desain Model Kelembagaan Guna Memperkuat Kinerja Usaha Mikro Kecil dan Menengah (UMKM) di Kota Magelang
Authors: Wiratama Adi , Al-Manan Oesman Raliby , Rosyidi Muhammad Imron
Published: September 2021

Mainan anak berbahan kayu adalah salah satu produk UMKM yang terdapat di Kota Magelang. Dalam perkembanganya, pelaku UMKM mainan anak masih memiliki permasalahan yang kurang mendukung kinerja dan berkembangnya usaha mereka. Salah satu permasalahan yang dihadapi ialah belum ada lembaga yang benar-benar memberikan manfaat dan menaungi usaha mereka. Tujuan dari penelitian ini adalah menemukan faktor-faktor kelembagaan dan mengkonstruk model kelembagaan yang berguna untuk memperkuat kinerja UMKM. Penelitian ini menggunakan metode analisis SEM dengan PLS dan AHP untuk menentukan bobot prioritas dari masing-masing variabel pendukung. Hasil dari penyusunan model diperoleh peningkatan kinerja sebesar 25% melalui kelembagaan serta faktor internal dan faktor eksternal mempunyai pengaruh sebesar 42% terhadap kelembagaan. Hasil dari analisis AHP penelitian ini diperoleh faktor-faktor kelembagaan dengan prioritas faktor internal kemudian faktor eksternal dengan nilai 0,535 dan 0,465. Prioritas pertama dari faktor internal adalah kapasitas produksi, kemudian prioritas kedua kualitas produk, permintaan pasar, modal pinjaman, dan jiwa kepemimpinan. Prioritas pertama dari faktor eksternal adalah bantuan modal, kemudian prioritas kedua penyiapan lokasi usaha dan penyediaan informasi, pendampingan, pembinaan, dan monitoring serta evaluasi. Nilai rasio konsistensi (CR) pada masing-masing matrik adalah kurang dari 0,1 dan dapat dikatakan seluruh matrik tersebut konsisten. Dalam upaya meningkatkan kinerja UMKM melalui kelembagaan, kelembagaan memerlukan dukungan dari faktor internal dan eksternal UMKM agar kelembagaan bermanfaat secara maksimal terhadap pelaku UMKM dan dapat memperkuat kinerja UMKM.
Struktura szkolnictwa w imperium rosyjskim na początku XIX wieku. Zarys problemu
Authors: Szmyt Andrzej
Published: September 2021

Having ascended the throne, Tsar Alexander established for the first time the Ministry of Education in 1802. Then the legal framework for the modern education in the Russian Empire was devised by a document called The Provisional Regulations of Public Enlightenment of the Russian Empire enacted 24th of January 1803, whereby six educational (school) districts were erected. The universities rode herd on schools. Next rescripts determined a.o. relations between schools and their policy. The system lasted until the fourth decade of the 19th century when Tsar started to restrict the autonomy of universities as well as unify their structure and educational system.
The United Kingdom against Russia’s attempts to maintain the zones of influence on the example of the Ukrainian crisis
Authors: Jureńczyk Łukasz
Published: September 2021

The subject of the paper are the United Kingdom’s actions against Russia's attempts to maintain its zones of influence, based on the example of the Ukrainian crisis. The introduction consists of a synthetic outline of the geopolitical rivalry between Russia and Great Britain. The next section discusses the attitude of the United Kingdom towards Russia’s attempts to maintain its zones of influence in the 21st century. The main section of the paper focuses on the United Kingdom’s actions against Russia’s military policy in Ukraine. The main thesis of the paper assumes that during the Ukrainian crisis, the UK has taken the most far-reaching measures so far to oppose Russia’s attempts to maintain zones of influence. The consequence of this is a significant deterioration in Russian-British relations due to the Ukrainian crisis. The leading paradigm is structural realism. The method of text source analysis was used in the paper.
The Ruling Elite in Russia: Continuity or Change?
Authors: Olszanecka Natalia
Published: September 2021

The third Vladimir’s Putin presidential term (2012-2018) was a significant period for the Russian Federation political security. Social protests, the annexation of Crimea, conflicts in eastern Ukraine and Syria, as well as economic sanctions and the deepening Russian isolationism - these are just some of the problems that Russian authorities had to face to ensure political stability. The aim of this article was to examine the changes and conflicts that occurred within President Putin’s inner circle between 2012 and 2018. The research was conducted according to content analysis method. It revealed that in 2012-2018 the attempts to weaken the decision-making power elite as a whole failed.
India’s foreign policy towards Central and Eastern Europe in 2014-2019
Authors: Dahl Michał
Published: September 2021

It has been said that Central and Eastern Europe can be seen as an interesting direction for Indian political and economic expansion. Both the data on diplomatic activity and India’s trade with the countries of CEE, however, prove that the region is not of key importance for New Delhi’s foreign policy. On the other hand, a steadily growing trade turnover allows assuming that the current situation will gradually change. The conclusions may be confirmed by the analysis of New Delhi’s diplomacy directions in the region. The Indian leaders (not the most important figures, taking into account symbolism and real significance) visited in the years 2014-2019 the CEE countries with the highest trade turnover with India, namely Poland, the Czech Republic, Hungary and Romania. They also paid visits to Bulgaria, Croatia and Serbia, that is countries with which India’s trade turnover is relatively low, but steadily growing. It may indicate a desire to establish more active diplomatic and economic involvement in this region than previously.
Bronisław Ferdynand Trentowski vs. panslawizm rosyjski
Authors: Starzyńska-Kościuszko Ewa
Published: September 2021

In the article I recreate and analyze the attitude of Bronisław Ferdynand Trentowski (1808-1869), one of the leading Polish representatives of “national philosophy”, participant of November Uprising and political emigrant, towards Russian Pan-Slavism. In opposition to Pan-Slavism, Trentowski introduced the idea of the Slavic Reich. Originally he based it on values specific to Western culture (occidentalism), and later on the conservative-catholic idea of Poland as the “Christ of Nations”. Combination of these two doctrines (Russian pan-Slavism and Polish messianism) offers an insight into historical premises of Polish and Russian national identities. The reconstruction of Trentowski’s position is proceeded by synthetic characteristics of Slavophilia and Pan-Slavism in Russia.
About the role of the text transformation in the process of cyclization of an author’s book of verse (“Sumerki” by E. A. Boratynsky and “Prostoe, kak mychanie” by V. Mayakovky)
Authors: Darvin Mikhail , Moreva Yuliya
Published: September 2021

In this paper the authors compare the two versions of the poetic dedication to P. A. Vyazemsky written by E. A. Boratynsky, the first one appeared in Pushkin’s “Sovremennik” magazine in 1836, the other one was published in Boratynsky’s book of verse “Sumerki” in 1842, and the untitled poem by V. V. Mayakovsky which appeared first in the book “Ya!” in 1913 and then in “Prostoe kak mychanie” in 1916. The transformations of the poems changed not only the meaning of the text but its function and played an important role in constructing of the artistic entity of the books. The authors pay attention not only to the minor changes of the text but also to the editorial and book printing details which are not less important for the meaning of the whole book.
Polish artists in Kazakhstan: with love to the steppe
Authors: Shaygozova Zhanerke , Sultanowa Madina
Published: September 2021

The article analyzes the cultural and creative heritage of artists of Polish descent who found themselves in Kazakhstan for various reasons in the period from the middle of the 19th to the end of the 20th centuries. In addition to their unconditional artistic value, the results of their creative efforts are of great scientific importance for modern Kazakhstan as unique ethnographic sources and documentary evidence of the daily graft and life of the Kazakh steppe. Domestic historical science already has a certain reserve dedicated to various sociopolitical, cultural and economic aspects of Kazakh-Polish relations, where the deportation of Poles and the formation of Kazakhstan’s Polonia are of particular importance. However, the creative heritage of Polish artists in Kazakhstan fell into the field of vision of scientists extremely occasionally. While its cultural and art historical context is able to shed light on many facets of the history, ethnography and culture of the Kazakh people. During the research, retrospective, comparative-historical and formal-stylistic campaigns were used. The result of the research is a retrospective analysis of the works of some of the most prominent Polish artists, due to various factors, for whom the Great Steppe has become not only a home, but also a source of inspiration and strength.
ADDITIONAL CHARACTERISTICS OF HYBRID COMPOSITES FOR FILLING TEETH UNDER LOCAL MOUNTING CLOCKS
Authors: Makeev V.F. , Kukhta V.S. , Kyrmanov O.S. , Skalsky V.R.
Published: September 2021

For the rational use of materials, it is necessary to have data on their ability to resist deformation and destruction. In particular, in each case it is necessary to have information on the stiffness, strength and resistance to destruction of materials in the specified operating conditions of the elements. To determine such strength characteristics of the material, certain studies are carried out.

According to the analysis of literature sources in the study of dental composites mainly determine the tensile strength (bending) and compression [2-10], because it is subjected to restore materials during their operation in the oral cavity.

The purpose of the study is to conduct a comparative analysis of the strength of hybrid composites of domestic and imported production during their local loading: Latelux (Latus, Ukraine), TETRIC N-CERAM (Ivoclar Vivadent, Liechtenstein), CHARISMA CLASSIC (Kulzer, Germany).

To conduct research, 10 samples of each dental polymer composite were made. Packaging and molding of the material into a specially designed form was performed in laboratory conditions at an air temperature of 18 210 C with their subsequent polymerization with a LED photopolymer lamp Bluephase 20i (G2) (Ivoclar Vivadent). Before the test, the samples were kept for 24 hours at a temperature of 370 C in saline.

The samples were loaded on the SVR-5 installation using a ball indenter (ball diameter mm steel SHX15, modulus of elasticity GPa, Poisson's ratio) with a speed of 0.002 mm/s.

The purpose of the study is to conduct a comparative analysis of the strength of hybrid composites of domestic and imported production during their local loading.

According to the results of experimental studies on the load of PB fracture, the Charisma Classic composite (5.72 ± 0.16 kN) has the highest strength, Latelux (4.23 ± 0.53 kN) the lowest, and Tetric N-Ceram (5, 03 ± 0.71 kN) occupies an intermediate position. To move the indenter, we obtained the following order of materials (in ascending order): Latelux (0.94 ± 0.11 mm); Charisma Classic (1.02 ± 0.04 mm); Tetric N-Ceram (1.03 ± 0.17 mm).