bluuebunny/crossref_metadata_2025 huggingface dataset:
The importance of specific autoimmune disorders in the pathogenesis of psoriasis and the prospects of immunobiological therapy of dermatosis
Authors: Tkachyshyna K.S.
Published: December 2022

Objective — to analyze the features of specific autoimmune disorders in patients with psoriasis, determine their importance in the pathogenesis of this dermatosis, and assess the prospects of immunobiological therapy for dermatosis.

Materials and methods. Based on an in-depth analysis of the results of modern special studies, the leading role of specific autoantigens and autoantibodies in the body of patients with this dermatosis has been confirmed in the pathogenesis of psoriasis.

Results and discussion. The article analyzes the importance of specific autoantigens, including keratin-17, LL-37, ADAMTSL5, and lipid antigens generated by PLA2G4D, which are essential in the pathogenesis of psoriasis. Emphasis is placed on the potential importance of immunobiological therapy, which significantly decrease levels of autoantigens LL-37 and ADAMTSL5 in areas of skin affected by psoriatic rash. The prospects of therapeutic approaches to the inhibition of cytokines derived from T cells and innate cells, such as IL-17, as well as to the inhibition of PLA2G4D or CD1a are also considered. Further study of specific autoimmune disorders in patients with psoriasis is important to improve therapeutic approaches to the treatment of psoriasis.

Conclusions. Autoimmune disorders, combined with genetic and a number of other factors, are one of the important of the development of psoriasis. Analysis of the results of current special studies has promising therapeutic value because, in addition to supporting approaches to inhibiting cytokines derived from T cells and dendritic cells, they support the development of approaches to inhibiting autoantigens directly.
The use of a long­pulse neodymium (LP­Nd:YAG) laser in treatment of patients with human papillomavirus (common and plantar warts)
Authors: Korolova Zh.V. , Vasilchuk Е.О.
Published: December 2022

Objective — to compare the effectiveness of a non-ablative method of treatment with the use of a neodymium laser and cryodestruction in patients with vulgar warts.

Materials and methods. 45 patients with vulgar warts, who were selected according to inclusion and exclusion criteria based on retrospective analysis of disease histories, were under observation. Three groups of patients were formed: 1st — treatment using the traditional method of laser therapy with a neodymium laser, 2nd — combined laser therapy with additional treatment of the affected areas with a laser scanner, 3rd — cryodestruction of warts. The Fotona SP Spectro new laser system — a long-pulse neodymium laser on yttria aluminum garnet (LP-Nd:YAG) with a wavelength of 1064 nm, a Fotona S11 scanner and Cry-Аc cryospray — was used for treatment.

Results and discussion. According to the observation data within a year from the start of therapy, the best result according to the criterion of the speed of achieving positive treatment results and the absence of the appearance of new elements was noted in patients of the 2nd group who underwent combined laser therapy. Significant advantages of laser therapy over cryodestruction have been determined, both according to the results of this study and according to the literature.

Conclusions. The combined method of laser therapy requires further careful study, but, without a doubt, is the most effective both in terms of aesthetic results and pathogenetic ones, since the action of laser radiation leads primarily to the neutralization of infected cells on the entire treatment area. Also, this combined technique allows reducing the recurrence of papillomavirus infection, and is practically painless for the patient. Based on the data obtained in the study, it can be concluded that the use of a neodymium laser is an effective alternative to cryotherapy, and significantly reduces the duration of treatment.
Oral allergy syndrome. Literature review
Authors: Bogomolov A.Ye.
Published: December 2022

Objective — to improve the methods of differential diagnosis and management of patients with oral allergy syndrome (OAS).

Materials and methods. A literature review is presented and diagnostic approaches and principles of management of patients with OAS are analyzed.

Results and discussion. OAS is a type of food allergy limited to the oral mucosa and triggered primarily by raw fruits, vegetables, flavorings, and nuts. Data on the prevalence of OAS vary considerably from study to study due to the use of different patient inclusion and exclusion criteria. However, there are reports of its frequency from 4.7 to more than 20 % in children and from 13 to 53.8 % in adults. It is reliably known that among the children’s population, OAS is mostly diagnosed in teenagers. Etiologically, OAS is caused by food allergens; mostly these are unprocessed fruits and raw vegetables that enter the patient’s oropharynx. Food allergens that cause OAS are actually inactivated by the gastric juice, so the reaction usually stops after the food is swallowed.

Conclusions. OAS is a subtype of food allergy that can be found in the practice of allergists, dermatologists, general practitioners. After contact with food, patients experience the following symptoms: itching of the lips and oropharynx; paresthesia; angioedema of the mucous membrane of the oral cavity, tongue, palate and oropharynx; sometimes hoarseness is possible. Modern therapy of OAS involves the use of a complex approach, which includes adherence to an elimination diet, pharmacotherapy, and allergen-specific immunotherapy. Antihistamines, corticosteroids, and adrenaline (intramuscular) are most often used in pharmacotherapy.
Polymorphism of VDR (Bsml) gene in patients with atopic dermatitis
Authors: Garibeh E.
Published: December 2022

Objective — to study the significance of the BsmI (rs1544410) gene of the VDR as a genetic molecular marker of the risk of atopic dermatitis (AD) development.

Materials and methods. The study included 54 patients with atopic dermatitis (the main group). The control group consisted of 32 people. All of the participants of this study lived in Podilliya region and had Ukrainian origin. The method of allele detection is based on the polymorphism of the length of restriction fragments that are obtained after treatment with certain restriction enzymes. BsmI polymorphism was studied, the international polymorphism code is rs1544410. Correct distribution of genotype frequencies was determined in accordance with Hardy—Weinberg’s law. Statistically significant differences were considered at p < 0.05.

Results and discussion. Analysis of the genotypes of single nucleotide polymorphism rs1544410 of VDR gene in patients with atopic dermatitis showed the predominance of the heterozygous variant (G/A). However, the proportion of allele A reached (47.2 ± 3.7) %, which may indicate a significant number of people with increased risk of atopic dermatitis development. According to our study of the single nucleotide polymorphism of the BsmI gene of the VDR among the subjects of the control group, the percentage of A/A-­genotype carriers was significantly lower than that of individuals with G/G­ (р = 0.028) and G/A-genotype (р = 0.023). While comparing the distribution of genotypes and alleles of single-nucleotide polymorphism BsmI VDR gene among individuals of the main and the control groups, we noted that allele A was more common in patients with atopic dermatitis (47.2 vs. 39.07 %, (OR 1.412; 95 % SI 0.203—0.978; р = 0.271). According to the obtained data, the carriers of the A/A-genotype dominated among the patients with severe atopic dermatitis, in contrast to the patients with a moderate course of the disease in whom G/A-genotype predominated. Carriers of the G/A- and G/G-genotypes also predominated among the patients with a mild course of the disease. Their number was significantly higher than that of the patients with the A/A-genotype (p < 0.05).Conclusions. Polymorphism of the VDR rs1544410 gene may be associated with an increased risk of atopic dermatitis development. Carriers of A/A-genotype of VDR rs1544410 gene are more common among patients with atopic dermatitis than among healthy persons of the control group.
MITOS - MITOS KEHIDUPAN SEBAGAI CIRI KHAS PADA MASYARAKAT JAWA KHUSUSNYA BERADA DI DESA MANISREJO, KECAMATAN TAMAN, KOTA MADIUN
Authors: Suryaningputri Dwi Amartani , Azahra Dwi Nabila , Nurjanah Syafina Putri , Darmadi Darmadi
Published: December 2022

Mitos merupakan salah-satu kepercayaan yang di ikuti dan memiliki kaitan yang sangat erat dengan budaya masyarakat jawa khususnya Kota Madiun, karena budaya jawa selalu mengangkat mitos dalam ritual-ritual yang dilaksanakan. Jenis mitos yang ada di Kota Madiun sangat banyak ragamnya, contohnya : Kerokan Bisa Menyembuhkan Masuk Angin, Menyapu Tidak Bersih Nanti Suaminya Brewokan, Burung Gagak Menandakan Ada Yang Meninggal, Anak Gadis Makan Di Depan Pintu, Keluar Saat Magrib, Bangun Siang Rejeki Dipatok Ayam. Itu merupakan suatu tradisi yang muncul dari dulu hingga sekarang yang masih di percaya oleh masyarakat jawa khususnya masyarakat Kota Madiun, terutama di Desa Manisrejo, Kecamatan Taman, Kota Madiun. Artikel ini bertujuan untuk mengetahui sejarah mitos dan untuk mengkaji kebenaran dari mitos yang dimunculkan tersebut. Artikel ini adalah penelitian lapangan (field research) yang bertempat di Desa Manisrejo, Kecamatan Taman, Kota Madiun. Penelitian ini menggunakan metode kualitatif deskriptif secara lisan maupun tulisan tentang orang-orang dan perilaku yang diamati. Dari penelitian ini, penulis menemukan bahwa Mitos yang ada di masyarakat adalah suatu kepercayaan masyarakat sekitar, kepercayaan terhadap mitos-mitos tersebut berasal dari sesepuh mereka yang dahulu, hingga sekarang masih terus bertahan dan menjadi suatu kepercayaan masyarakat sekitar.
BUDAYA BROKOHAN KELAHIRAN BAYI DI DESA JATIREJO, KECAMATAN WONOASRI, KABUPATEN MADIUN
Authors: Purwaningsih Riani , Dwi Putri Rahel Elsa , Triasroza Alrohma Nikmawati , Darmadi Darmadi
Published: December 2022

Permasalahan penelitian ini adalah (a) Bagaimanakah deskripsi upacara upacara brokohan kelahiran bayi di Desa Jatirejo, Kecamatan Wonoasri, Kabupaten Madiun. (b) Bagaimanakah deskripsi makna dan fungsi upacara upacara brokohan kelahiran bayi di Desa Jatirejo, Kecamatan Wonoasri, Kabupaten Madiun. (c) Bagaimanakah pandangan rasionalisme tentang upacara brokohan kelahiran bayi di Desa Jatirejo, Kecamatan Wonoasri, Kabupaten Madiun. Penelitian ini menggunakan pendekatan arketipal, antropologi budaya dan antropologi sastra. Penelitian ini tergolong sebagai penelitian kualitatif, penelitian yang tidak menggunakan angka sebagai data. Sedangkan sumber data dalam penelitian ini berupa data kata-kata atau tindakan orang yang diwawancarai atau diamati. Sumber data utama adalah catatan hasil wawancara dan observasi dengan narasumber. Hasil penelitian ini menunjukkan deskripsi aspek simbolisme yaitu bentuk atau lambang, makna, dan fungsi, serta pandangan rasionalisme dari budaya brokohan kelahiran bayi. Masyarakat Jawa menganggap budaya brokohan kelahiran bayi, sebagai ritual yang patut diperhatikan secara khusus. Karena pada hakikatnya, tradisi ini adalah memohon keselamatan kepada Allah SWT agar anak yang telah dilahirkan sehat, selamat, dan selalu mendapatkan rezeki yang lancar
Nigerian Supreme Council for Islamic Affairs and the Quest for Unity of Muslim Ummah in Nigeria
Authors: Suberu Ibrahim
Published: December 2022

Abstract

The emergence of Islamic organizations during the colonial era caused disunity among the Muslim Ummah in Nigeria. The quest to coordinate the affairs of these organizations and to unite the Muslim Ummah nationally under one umbrella led to the establishment of the Nigerian Supreme Council for Islamic Affairs (NSCIA) in 1973. This study, therefore, examines the role of NSCIA in addressing the challenges of disunity confronting the Muslim Ummah in Nigeria. Data were collected from oral interviews, questionnaires and secondary sources. A multidisciplinary approach was adopted using a combination of historical, phenomenological and sociological methods of data analysis. The theoretical framework is built on the theory of Asabiyyah by Ibn Khaldun and the theory of structural functionalism. The study discovered that the need to protect Islamic faith from colonial influence gave rise to the emergence of Islamic organizations in Nigeria. It is also discovered that Nigerian Muslims are divided along ethnic, regional and organizational lines. The study shows that despite the establishment of NSCIA in 1973, to foster unity, there are still issues bothering on disunity among the Muslim Ummah in Nigeria. Perpetuation and nothernization of the council's leadership is discovered to be a factor responsible for the inefficiency of the Council to unite the Ummah. This work recommends a review of the constitution of NSCIA for effectiveness. It also suggests rotation of its headship and that serious effort should be made by the Council at cultivating the spirit of unity among Muslims Ummah.
Role of Islamic Microfinance in Socio-economic Development
Authors: Arif Muhammad , Sultan Raja , Hussain Zahid
Published: December 2022

Prime Minister Imran Khan introduced an interest-free loan programme through a public-private collaboration as part of the Kamyab Jawan Programme 2022. A huge number of low-income and susceptible households benefited immensely from this programme. This program's goal is to end poverty by giving low-income individuals interest-free loans to launch their own small businesses. Primary data for this research was gathered from 184 beneficiaries of the lenders who received interest-free loans from the prime minister under the Kamyab Jawan programme in two districts of Sindh. Records of beneficiaries were taken from two chosen districts, and each component was chosen using a simple random sampling method. For this study, study participants of both genders were represented equally. A self-managed device was used to gather data directly from the recipients of the Prime Minister's interest-free loans. The findings show that the Prime Minister's Interest Free Loan Program is significantly enhancing the socioeconomic, economic, and social and political wellness of the recipients. Most survey participants reported significantly improved financial, personal, and sociopolitical wellness. Enhanced social, financial, and political wellness were also found to be related to interest-free loans in one sample binominal assessment. The majority of participants expressed satisfaction with the interest-free loan programme offered by the Kamyab Jawan programme, believing that it had a significant impact on decreasing the level of security vulnerabilities and poverty following the COVID-19 disease outbreak. The study's author suggested that this program's based on geography reach be increased in some way to attain as many poor and vulnerable communities as possible.
EKONOMI MONETER ISLAM MASA DEPAN
Authors: Zahra Sufiani
Published: December 2022

Sistem moneter masih terpaku pada tingkat suku bunga. Penerapan sistem moneter islam selain dilihat dari fasilitas sasaran kebijakan yang efektif, namun juga berjalannya sistem secara sehat dan adil. Penerapan prinsip-prinsip islam dalam sistem moneter, ada beberapa hal yang harus perhatikan yaitupenyelarasan sistem moneter, peningkatan kebutuhan sektor riil hingga aliran distribusi kekayaannya merata. Penerapan prinsip islam dalam sistem moneter juga harus dibarengi dengan peran dan dukungan pemerintah.Peluang penggunaan uang emas dalam seluruh kegiatan transaksi bukanlah hal yang tidak mungkin. Hal tersebut dapat dicapai selama regulator negara tersebut sudah memutuskan dan mengesahkan uang emas secara legal dan disetujui oleh seluruh negara di dunia.Uang elektronik sebagai alat pembayaran diperbolehkan asal memenuhi unsur-unsur yang telah ditetapkan oleh DSN-MUI juga terhindar dari maysir,gharar, dan riba serta sejalan dengan maqashid syariah.Dalam mendorong sumber pertumbuhan ekonomi baru di masa depan,ekonomi moneter islam lebih memfokuskan pada aspek sektor riil yaitu pada pemberdayaan umkm, serta pemenuhan menyeluruh pada tiga sektor yaitu sektor swasta, sektor publik, dan sektor sosial
Pasar monopolistik dan oligopoli
Authors: Ali Nurfadilla Nur
Published: December 2022

Tulisan ini dibuat untuk memenuhi tugas dari mata kuliah ekonomi mikro yang memuat tentang materi yang telah disampaikan dan didiskusikan di kelas bersama dosen kami. Dalam tulisan ini memuat pengenalan singkat mengenai materi "pasar monopolistik dan oligopoli", Penulis berharap bisa membantu pembaca dalam menambah wawasan dan penulis juga menyadari bahwa apa yang ada didalam tulisan ini masih belum memuat semua informasi yang ada tentang judul materi yang telah disebutkan sebelumnya.
UAS Pend IPS
Authors: Putri Amalia
Published: December 2022

IPS is a subject that has an important role in education. Because social studies studies various fields of history, economics, politics, technology and so on. Therefore, you must study IPS so that it can be used as a tool to solve everyday life problems, although many people view social studies as the most common field of study saturate. At every level of education is inseparable from social studies subjects from elementary school to university.
stabilitas sistem keuangan dan mineter islam
Authors: SYAHRA AISYAH
Published: December 2022

Pengalaman krisis global yang terjadi dalam beberapa tahun terakhir disebabkan oleh ketidakstabilan sistem keuangan yang diciptakan oleh lembaga perbankan.
Ekonomi Moneter Islam Masa Depan
Authors: H Yuris Huswatun
Published: December 2022

Penyelarasan prinsip-prinsip konvensional dengan prinsip Islam, atau bahkan yang sifatnya transformasi, harus mampu mengakar tidak hanya pada masyarakat secara individu namun juga masyarakat secara umum dan diikuti juga dengan transformasi dari sisi institusional. Institusi dan otoritas moneter diharapkan mampu menciptakan regulasi dan kerangka untuk penerapan nilai- nilai Islam secara menyeluruh dalam praktik sistem moneter. Masyarakat dan institusi memiliki peran masing-masing yang saling mendukung demi terciptanya iklim kondusif dan praktis dalam rangka pengaplikasian sistem moneter yang sesuai dengan prinsip Islam. Institusi harus merumuskan aturan-aturan yang mendukung agar pelaksanaannya tetap berada di jalur nilai-nilai Islam1.
Dampak Resesi dalam Perencanaan Bisnis 2023
Authors: Wirahmaja Michael Jonathan
Published: December 2022

Pada tahun 2023 banyak kabar yang memuat tentang resesi, dalam artikel ini akan banyak membahas tentang cara perencanaan bisnis pada masa resesi
OJK DAN SISTEM MONETER INDONESIA
Authors: Muthmainnah
Published: December 2022

Otoritas moneter dalah suatu entitas yang memiliki wewenang untuk mengendalikan jumlah uang yang beredar pada suatu negara dan memiliki hak untuk menetapkan suku bunga dan parameter lainnya yang menentukan biaya dan persediaan uang.
PRAKTEK KERJA MONETER ISLAM
Authors: T Andi Marhuni
Published: December 2022

Kebijakan Moneter adalah suatu usaha dalam mengendalikan keadaan ekonomi makro agar dapat berjalan sesuai dengan yang diinginkan melalui pengaturan jumlah uang yang beredar dalam perekonomian. Usaha tersebut dilakukan agar terjadi kestabilan harga dan inflasi serta terjadinya peningkatan output keseimbangan. Hampir semua sektor ekonomi kapitalis terkait dengan sistem bunga sehingga sektor moneter lebih cepat berkembang dari pada sektor riil. Hal ini disebabkan karena sektor moneter lebih cepat memberikan keuntungan dari pada sektor rill.
Stabilitas Sistem Keuangan dan Stabilitas Moneter
Authors: R Nurul Zahra Zahirah
Published: December 2022

Resume ini untuk memenuhi tugas mata kuliah ekonomi moneter
The dynamics of Foreign Direct Investment (FDI) inflows in developing economies: Evidence from Bangladesh
Authors: Islam Mohammad Mohidul
Published: December 2022

Considering the importance of economic development in attracting Foreign Direct Investment (FDI) inflows to the developing economies, this study aims to investigate the relationship between FDI inflows and economic development in Bangladesh using annual time series data for the period of 1991 to 2020. The empirical analysis is performed employing the Autoregressive Distributed Lag (ARDL) bound test method in order to find out the long-run as well as the short-run relationship between FDI inflows and economic development. The empirical evidence from the study indicates that the economic development indicator does not have any statistically significant positive relationship with FDI inflows in the long-run. Other variables, namely the interest rate and export receipts, have a significant statistical relationship with FDI inflows, and the right direction of these two variables in terms of the expected sign of the coefficients shows that to some extent there has been an insightful economic relationship. However, in the short-run, such a relationship between FDI inflows and economic development is statistically justified, where the negative coefficient of the error correction term indicates the dynamic adjustment to the long-run equilibrium has been found to be made in a consistent manner, which is supported by the statistical theory. Finally, this study also suggests that the government should take proper measures to attract higher FDI inflows in order to ensure the faster socio-economic development of the country as a whole.
EKONOMI MONETER ISLAM MASA DEPAN
Authors: Muhajir
Published: December 2022

Penggunaan uang emas dapat saja dicapai selama regulator negara tersebut sudah memutuskan dan mengesahkan uang emas secara legal. Selain itu, penerimaan dan persetujuan dari negara-negara lain juga diperlukan demi tujuan mencapai penggunaan uang yang sesuai syariat Islam. Maka dari itu, kerjasama antara seluruh negara terutama negara yang mayoritas Islam sangat penting untuk dapat mencapai kembali penggunaan uang emas, sehingga untuk perdagangan internasional digunakan mata uang tunggal.
A Virtual Reality Study Investigating the Train Illusion
Authors: Kooijman Lars , Asadi Houshyar , Mohamed Shady , Nahavandi Saeid
Published: December 2022

The feeling of self-movement that occurs in the absence of physical motion is often referred to as vection, which is commonly exemplified using the train illusion analogy (TIA). Limited research exists on whether the TIA accurately exemplifies the experience of vection in virtual environments (VEs). Few studies complemented their vection research with participants’ qualitative feedback or by recording physiological responses, and most studies used stimuli that contextually differed from the TIA. We investigated whether vection is experienced differently in a VE replicating the TIA compared to a VE depicting optic flow by recording subjective and physiological responses. Additionally, we explored participants’ experience through an open question survey. We expected the TIA environment to induce enhanced vection compared to the optic flow environment. Twenty-nine participants were visually and audibly immersed in VEs that either depicted optic flow or replicated the TIA. Results showed optic flow elicited more compelling vection than the TIA environment and no consistent physiological correlates to vection were identified. The post-experiment survey revealed discrepancies between participants’ quantitative and qualitative feedback. Although the dynamic content may outweigh the ecological relevance of the stimuli, it was concluded that more qualitative research is needed to understand participants’ vection experience in VEs.
The crucial roles of biodiversity loss belief and perception in urban residents’ consumption attitude and behavior towards animal-based products
Authors: Nguyen Minh-Hoang , Le Tam-Tri , Jones Thomas , Vuong Quan-Hoang
Published: December 2022

Products made from animal fur and skin have been a major part of human civilization. However, in modern society, the unsustainable consumption of these products – often considered luxury goods – has many negative environmental impacts. This study explores how people’s perceptions of biodiversity affect their attitudes and behaviors toward consumption. To investigate the information process deeper, we add the moderation of beliefs about biodiversity loss. Following the Bayesian Mindsponge Framework (BMF) analytics, we use mindsponge-based reasoning for constructing conceptual models and employ Bayesian analysis aided by Markov Chain Monte Carlo (MCMC) algorithms on a dataset of 535 Vietnamese urban residents. The results show that people’s preference for using products made from animal skin/fur is negatively associated with perceived consequences of biodiversity loss when they believe biodiversity loss is real and a major problem. In contrast, if urban residents believe biodiversity loss is unreal or not a significant issue, the association between perceived consequences of biodiversity loss and personal preference happens in the opposite direction. The same effects of biodiversity loss perception on people’s possession of skin/fur products was not found, indicating a more complex information process on behaviors compared to attitudes. Nevertheless, in the scenario that people believe biodiversity loss is not a significant issue, the higher the perceived consequences of biodiversity loss are, the greater number of animal-based products they likely own. Our results suggest that policymakers should not neglect the factor of personal belief besides knowledge and awareness in environmental campaigns.
Effect of COVID -19 Pandemic on Mental Health of Students: A Contemporary Literature Review
Authors: Gyawali Kalpana
Published: December 2022

The globally increasing trend of COVID -19 pandemic has got worldwide attention from several nations. Along with physical health, pandemic diseases have shown a tremendous negative impact on mental health in the general population throughout the world. To find out the impact of this pandemic on the mental health of students, a systematic review of different national and international literatures was carried out to complete this study. Elevated anxiety, depression, stress, and sleeping disorder were found as the major mental disorders among the students. Most of the results of reviewed studies were based on online survey. In Nepalease context studies on the impact of Covid -19 on mental health are very limited, hence the findings might be useful to explore the possible mental problems among the Nepalese students; and  the result will be  helpful to follow the necessary further steps to minimize the COVID-19 induced mental problems among the targeted group.
Challenges Faced by Teachers in Teaching English at Basic Level
Authors: Saud Mohan Singh
Published: December 2022

Teaching English as a foreign language can be a challenging job in non-English speaking countries like Nepal, particularly when English is taught as a subject. In consideration of English as an international language in Nepal, this study explored the challenges faced by English language teachers in teaching English at basic level pubic school education in Dhangadhi Sub-Metropolitan City of Kailali district of Nepal. Using a phenomenological design under qualitative research, the study included four English language teachers selected through non-random, purposive sampling technique. Semi-structured interviews were used to collect information from the participants, and then the data were analysed and discussed thematically in line with the research questions. As the results revealed, the key challenge concerned large class sizes, particularly when the students came from poor economic family backgrounds, those who also had a poor English language base with low vocabulary achievement. Managing larger classes, recruiting more teachers having English language proficiency and managing infrastructures along with extending class hour can be its implications. Exposing students to English forms the base.
Analyzing the Educational Attainment of People in Nepal from Gender Perspective
Authors: Karki Rita Devi , Karki Tek Mani
Published: December 2022

Education is a key tool for human civilization but many people are deprived of it and do not have equal chance to achieve it from gender point of view in society, though everyone has an equal right to get it. In this context, this study tries to explore the literacy status, educational attainment. The major concern of preparing this article was to study this issue extracting the data from two immediate past censuses of Nepal and analysing them by using the Microsoft Excel programme. Humanities and Arts, Business and Administration, Education, Science, and Social and Behavioural Science are supposed to be more selected subjects of study for both males and females at the national level. More gender gap in terms of literacy and level of education seems to occur though the level of education increases in all provinces.
Factors Influencing Head Teacher's Leadership: A Case of Community School in Kathmandu Valley
Authors: Sherpa Dawa , Baraily Khagendra
Published: December 2022

This study aimed to explore the factors influencing leadership of head teacher.  For this purpose, interpretative phenomenology was employed. Five head teachers having more than ten years' experience in different community secondary schools of Kathmandu valley were selected as participants for their lived experience and perception through purposive sampling. Information was collected through participants by in-depth interviews and semi-structured questionnaire to draw the perception and experience of the participants. In interviews, we attempted to interpret respondents' explanations, experiences, struggles, and evidences related to head teacher. Interviews were transcribed as verbatim and coded to generate themes. Themes were analyzed with reference to the essence of transformative leadership theory to reach in conclusion. The study finding showed that size of organization, level of interaction, decision making skill, problem solving skills, and team efforts are influencing factors for effective leadership. Head teacher’s leadership can be positively influenced in small organization but professional development of staffs can be negatively impacted. Frequent collaboration among stakeholders and interpersonal relationship among staff influences the leadership of head teacher positively. The tactful leadership skills for problem solving inspired the head teacher to strengthen the capacity of the organization along with team effort. Thus, the leadership of head teacher in community school needs to be sensitized to apply appropriate size based on stakeholder. The intensity of collaboration is required to be maintained with the principles of rich communication and team effort.
Editorial 30(1)
Authors: Luitel Binod
Published: December 2022

Not Available.
Metabesity-journey starts before birth?
Authors: Maskey R.
Published: December 2022

No abstract available.
Spectrum of endocrine disorders in a hospitalized patient in a Tertiary University Hospital, Nepal
Authors: Yadav G. , Paudel G. , Gautam A. , Yadav R. , Khatiwada P. , Raut P. , Guragain P. , Chaturvedi M. , Maskey R.
Published: December 2022

Background: The epidemiological spectrum of endocrine disorders in hospitalized patients is not much explored in developing countries. Therefore, the spectrum to visualize a complete picture of the endocrine-related disease is still missing.

Aims: The study aims to find the spectrum of endocrine-related-disorders in a hospitalized patient, characterize demographic variables, and the duration of hospital stay of patients.

Methods: This was a retrospective study of medical records of admitted cases between January 2014 to December 2018 in the Medicine Ward of BPKIHS. Records were retrieved from the Medical office and were entered into Excel and then transferred to SPSS and were analysed.

Result: Out of 26,590 admitted cases,1141 (4.3%) had endocrine-related-disease. This includes 565 males and 576 females (1.02: 1 ratio) with an overall mean age of 52.81 ± 16.21 years and median (IQR) age 53 (42-64) years. Among which 904 (79.2%) had Diabetes mellitus, 118 (10.3%) had Metabolic Disorders, 38 (3.3%) had Disorders of Thyroid gland, 38 (3.3%) had Other Nutritional Deficiencies, 29 (2.5%) had Disorders of other endocrine glands, 7 (0.6%) had other disorders of glucose regulation and pancreatic internal secretion, 5 (0.4%) had Overweight, obesity and other hyperalimentation, 2 (0.2%) had Malnutrition.

Conclusion: Diabetes and Metabolic disorders are the main components of the spectrum of endocrine disorders in admitted cases. Emphasizing the resources essential for further investigation will help both in dealing with and managing the cases of endocrine disorders.
Longitudinal Solid Polarized Target for CLAS12
Authors: Pandey P. , Kuhn S. , Lagerquist V. , Keith C. , Brock J. , Maxwell J.
Published: December 2022

The Run Group C suite of experiments measure multiple spin-dependent observables by scattering an 11 GeV electron beam from longitudinally polarized nucleon targets inside the CLAS12 spectrometer in Hall B at Jefferson Lab. The dynamically polarized target built for these experiments has been extensively tested by the JLab Target Group in the Experimental Equipment Lab using an auxiliary 5 T magnet. We report on the operational experience with the target, the benchmarks achieved so far (using various polarizable materials) as well as the complete target setup, experimental readiness, and its present status. Our results show that all target components work well and the project has started successfully with the first beam on June 11, 2022.
BibliometrÃ­a sofisticada
Authors: Aguillo Isidro F.
Published: December 2022

Una llamada a aplicar una bibliometrÃ­a mÃ¡s sofisticada, profesional, con mÃ©tricas de calidad tÃ©cnica y cientÃ­fica que supere la actual prÃ¡ctica incorrecta y fÃ¡cil en los procesos de evaluaciÃ³n de la actividad cientÃ­fica.
Аnalysis of the efficiency of the application of mobile autonomous power plants under critical conditions energy infrastructure.
Authors:   State Institution of Higher Education «Donetsk National Technical University», N. SAVCHENKO
Published: December 2022

A critical analysis of the design features of mobile autonomous power plants was carried out according to a new approach to their classification. The issues of the efficiency of the operation of existing mobile power plants in terms of technical characteristics are considered in order to identify the optimal energy-efficient options for use in a critical state of the country's energy system. The prospects for the introduction of hybrid mobile power plants built on the principle of duplication of alternative power sources with a different nature of the energy potential for conversion into electrical energy are substantiated. At the first stage of the analysis, it was revealed that among the wide variety of existing types of mobile power plants, there is almost no picture regarding the comparative characteristics of the energy efficiency of their use, which allows the consumer to determine the optimality of a particular design to ensure equality between the economically justified cost and the technical capabilities of the device for the purpose of reliable power supply. The validity of the optimal composition of a mobile autonomous power plant in each case is a difficult task for analysis according to a specific technical task, which is formed by the consumer. All influencing factors must be taken into account when choosing the design of a mobile power plant for each particular case, namely technical, economic, legislative, operational, climatic and environmental. As a result of the enlarged analysis of mobile power plants by type of energy conversion, it was found that all the considered classes and types of mobile power plants have both advantages and disadvantages, but during the period of destabilization of the processes of generation and distribution of electrical energy and the impossibility of a quick recovery of the country's energy sector, they are the only way out of the energy crisis, and it is necessary to apply all possible structures to exit the energy infrastructure from a critical state. To rank the available types of mobile power plants in terms of optimality and energy efficiency, further detailed analysis is required according to their technical characteristics.
Intelligent diagnostics of electrical networks
Authors:   State Institution of Higher Education «Donetsk National Technical University», D. OSTRENKO , O. KOLLAROV ,   State Institution of Higher Education «Donetsk National Technical University»
Published: December 2022

As follows from the conducted analysis [1-2], artificial intelligence has a great impact on modern energy as a whole, and it has also reached the electric power sector, especially "intelligent" networks with a high degree of automation, which closely interact with renewable energy sources. Here, artificial intelligence has gained widespread use in order to predict the level of illumination of a photovoltaic panel and estimate the output power of solar power plants. Considering the fact that artificial intelligence is a powerful and popular tool that is widely used in renewable energy (in particular, in photovoltaic), it is important to understand to what extent this tool can be used when creating a forecast of the generation of electrical energy at the output of a photovoltaic plant. It is becoming clear that with the help of artificial intelligence, it is necessary to increase both energy efficiency and accuracy values in the power grid, since electronic computing machines can process more data than an operator can in a given time period. When diagnosing the quality of electrical energy in a photovoltaic plant, it is important to observe certain provisions, namely: - adequate, for a specific task, the time of control. As a rule, this parameter must be installed in the system in advance; – determination of the number of electrical equipment and/or power system nodes for monitoring; – assignment of the limit level of parameters for measurement; – the choice of the method for performing the analysis of the measured data; – choosing the type and location for saving the received data, also here it is worth providing for compatibility with other devices in the electrical network, for example, control or signaling devices. In order to indicate the main tasks for the diagnostics system in the photovoltaic plant, which will include artificial intelligence, a structural diagram was created that indicates what tasks must be done in each link of the electrical network. It is worth noting that the structure of the diagnostic system can be divided into several components according to their physical location in the system under study. So, for example, sensors are responsible for all data collection in the power grid. Of greater interest are the links that perform monitoring in the power grid, as well as develop conclusions based on the conducted monitoring and accumulate databases for decision-making. An artificial neural network is responsible for fulfilling these requirements, and its data set for training and retraining can serve as a database.
Sovershenstvovanie pedagogicheskikh priiomov razvitiia logicheskogo myshleniia doshkol'nikov posredstvom konstruirovaniia iz bumagi
Authors: Bulat Roman Evgenevich , Sharipova Anastasiia Pavlovna
Published: December 2022

A study aimed at improving pedagogical methods for the development of logical thinking in preschoolers through paper construction revealed that: origami paper design is not part of the main educational program of preschool education, but is used either fragmentarily or in additional classes. At the same time, the pedagogical purposeful management of the development of thinking of preschoolers is based on methods and techniques, most often limited to the methods of imitation and repetition. The study reveals a contradiction between the objective need to introduce significant substantive adjustments to the basic educational programs of preschool education and the insufficient readiness of teachers to implement it. The development and implementation of the technology of pedagogical purposeful management of the development of thinking in preschoolers through the construction of paper using the origami technique made it possible to resolve the identified contradiction and increase the effectiveness of the development of thinking among students.
Latin as a nature of deontological principles of medicine and humanitarian values of teaching and learning at medical universities
Authors: Pavliuchenok Marina Borisovna , Uliankova Natalia Aleksandrovna
Published: December 2022

In their work, the authors reveal the applied role of the Latin language as an important propaedeutic discipline in the formation of professional ethical principles and moral qualities among students of the medical university, which they need both in the learning process and in future medical activity. The special influence of humanitarian comments on professional vocabulary and aphorisms of medical and general cultural content on the comprehensive development of students' personality is also considered. Significant aspects of this influence are orientation to humanistic values and self-development, increasing the level of general culture and education, understanding the essence and meaning of concepts, showing interest in science and language learning, improving oral speech skills and the ability to express their thoughts competently and intelligently, improving perception and memory training. In this paper, it is noted that the stereotype of the Latin language as an insignificant discipline, where its role is reduced only to the training of terminologically competent specialists, has long been outdated. The authors tried to present the Latin language not only as a narrow-profile subject for future physicians, but as the language of Antiquity and its great heritage, as the language spoken and written by famous philosophers, orators, poets and doctors, as a language that has provided and still provides cultural and spiritual influence on the personal formation of people.
The conclusions obtained in the course of the work are of interest to the teaching staff of the Latin Language Department at the Medical University and medical students.
Spetsifika prepodavaniia matematiki v tekhnicheskom vuze: opyt raboty
Authors: Genvareva Iuliia Anatolevna , Marchenkova Natalia Georgievna
Published: December 2022

This scientific work examines the specifics of teaching the discipline «Mathematics» for students of technical and engineering specialties. The problems of teaching mathematics at the university are analyzed, as well as ways to overcome them are considered. The forms of work with students within the discipline that allow for high-quality mathematical training of future engineers are described in detail.
O vozmozhnostiakh i perspektivakh obucheniia nemetskomu iazyku v vysshei shkole
Authors: Sokolova Galina Aleksandrovna
Published: December 2022

This chapter deals with the German language and its national variants which are spread in Switzerland and Austria. The work analyzes everyday situations of written and oral communication, emphasizes the important role in mastering the communicative and socio-cultural competencies by future teachers of foreign languages, highlights the importance of introducing the study of the national versions of the German language into the educational process.
Formation of grammatical forms of full-meaning parts of speech in Ukrainian and Polish languages
Authors: Lesiuk Mykola
Published: December 2022

The aim of the article is to find out and explain the reasons that differentiate these two grammatical systems and show that common which unites them and gives the basis to consider them closely related. The basis for writing this article served many years of experience in teaching the history of the Ukrainian language compared to other Slavic languages, and the source base, that the author relies on, are the numerous works of Ukrainian and Polish linguists dedicated to the history of Slavic languages.

Basic methods that were used while writing this article – are descriptive and comparative, due to which the author was able to show a great similarity in grammatical forms of main (independent) parts of speech and at the same time differences in these forms caused by these or those reasons that arose in the process of development of languages. In this article those language issues were given, in the process of studying of which the students, who study Polish, had some difficulties. This, in particular, concerns masculine and non-masculine personal forms within the limits of every full-meaning part of speech in Polish, namely here separate forms of masculine were singled out that concern just the males. As for Ukrainian, there isn’t such a variety of declinable forms, that means it went through larger unifications, moreover, if we take the system of verbs (separate verb forms) – under the influence of female samples. Functioning of these grammatical forms is shown in the system of declension of a noun, adjective, pronoun, numeral and a verb.

To conclude, this article will give students and all those who are interested in the language of the nation, namely the representatives of both countries – Ukraine and Poland – the understanding of main grammatical regularities and features of both closely related languages.
Poetic Skovorodiniana of Dnipro region
Authors: Biliatska Valentyna
Published: December 2022

Research of Hryhorіy Skovoroda phenomenon is significant, but his creative heritage has not been sufficiently studied especially the artistic interpretation of his figure. The poetic image of the Ukrainian philosopher in the lyrics of Dnipro region writers was not the object of scientific study. In the poetry of Dnipro residents Skovoroda is a key figure of our culture, it is a measure of the truth of life values, the personification of the spirit strength, a source of inner harmony and spiritual insight: «gray – haired lubomudr» (S. Burlakov); «judge of earthly vanities», «harsh philosopher», «affectionate judge», «thoughtful» (V. Korzh); «Immortelle-ozonets» (H. Prokopenko).

Assimilating the philosophical and aesthetic experience of Hryhorіy Skovoroda, artistic and ideological aspects of his heritage, the poets of Sicheslav region poetically interpreted the leading philosophical theory of the sage – cognition: by embracing himself and the world around him, a person asserts himself, develops his natural inclinations, chooses his own path and fulfills his earthly purpose; they focused on his teaching about work as a necessity of being to which God called rewarding him with talent and giving him the ability to know himself (S. Burlakov «Slobozhanshchina, I love your gardens», O. Zaivyi «Skovoroda», V. Zemliany «Skovoroda», V. Korzh «From the life of Hryhorіy Skovoroda. Rest», A. Kravchenko-Rusіv «Hryhorіy Skovoroda», N. Nikulina «Over the books of Skovoroda», H. Prokopenko «Testament of Skovoroda», H. Svitlychna «Skovoroda», I. Sokulsky «Skovoroda», K. Chernyshоv «It happens that the spirit of Skovoroda»).

In the poetry of Dnipro region artists symbolic images of Skovoroda are revealed: roads as a fact of the sage’s biography and inner world; garden as a kind of model harmony with nature, God, the world, and with himself, which corresponds to the biblical Garden of Eden and is associated with the immortality of the philosopher and his way of life; hearts and souls as a constant struggle between good and evil, helping to overcome all misconceptions and learn the true essence of a person. The works of poets were written mainly in the 70s and 80s of the twentieth century, but the lyrics interpreted this outstanding personality as a carrier of freedom, a carrier of «free spirit» (K. Chernyshоv), «son of freedom» (H. Prokopenko), and a «freedom-loving person» (A. Zaivyi).