bluuebunny/crossref_metadata_2025 huggingface dataset:
Transcriptomic profiling against Globodera pallida in resistant and susceptible potato roots
Authors: Carreño Hans , Ponce Olga , Casanova Regina , De la Cruz Germán , Neyra Edgar
Published: March 2020

Globodera pallida is a white potato cyst nematode present in the Andes, which causes huge losses to Peruvian farmers. An RNA-seq analysis allowed the identification of candidate genes that could mediate resistance against this pathogen. Two varieties, “María Huanca” (Solanum andigena) clone resistant (CIP 279142.12) and “Chimbina Colorada” (Solanum chaucha) (CIP 701013) clone susceptible to G. pallida, were used to identify differentially expressed genes. Total RNA from roots was extracted 72 hours post inoculation with second stage juveniles. Sequencing was done using the Illumina Hiseq 2500 platform. Reads were screened for quality issues and then mapped to the reference potato genome (clone DM1-3516 R44 v4.03). Here, we report 27717 and 27750 genes expressed in the resistant and susceptible variety respectively. The comparative analysis of expression identified 100 candidate genes. 91 genes were associated with resistance to G. pallida with Fold Change ≥ 2 (p <0.05). The remaining 9 R genes had Fold Change ≤ 1. We show differences in the expression of an NBS-LRR protein similar to Gro1-8, genes linked to late blight and TMV virus resistance.
Environmental Biotechnology
Authors: Hernández- Macedo Maria Lucila , López Jorge A. , Barrios Eguiluz Katlin Ivon , Salazar-Banda Giancarlo Richard
Published: March 2020

The various industrial sectors, as well as livestock and agricultural activities, are increasing the production of inputs to meet the demand of the worldwide demographic explosion, making a challenge the clean maintenance of water, soil, and air. Therefore, the search for solutions for a pollutant-free environment without compromising economic development has become extremely important. Thereby, biotechnological studies in order to solve environmental issues have been gaining extensive attention through the coupling of technology procedures to biological systems as sustainable solutions to remediate contaminated areas. In this sense, this review covers topics such as the role of Omics era in microbial environmental biotechnology for pollution control as well as the microbial fuel cell use in energy production. Moreover, phytoremediation and the perspective of applying chemical methods are approached as environmentally friendly tools for the pollutant control to improve remediation processes.
Single molecule sequencing of nucleic acids in real time (SMRT) to characterize transcriptomes and mRNA isoforms
Authors: Ponce de León F. Abel , Guo Yue , Crooker Brian
Published: March 2020

Our efforts are oriented to assess bovine Y-chromosome gene expression patterns. One set of genes that are of interest are the so-called X-degenerate Y-chromosome genes that are located in the male-specific region of the Y-chromosome (MSY). This region contains 95% of the DNA of the Y chromosome. These genes are single copy and have an X-chromosome homolog. Both, the Y-encoded and X-encoded homologs have ubiquitous expression profiles. However, some genes, like SRY that regulates male sex determination, have functions that are more specific. Identifying DNA sequence differences between these homologs will allow evaluation of their spatial and temporal expression patterns. Identification of the Y-encoded mRNAs and their isoforms will allow our understanding of tissue specific expression of isoforms in male tissues. The latter will facilitate our evaluation of gene function in male sex differentiation and fertility. Hence, we hypothesized that each of these X-degenerate gene homologs generate isoforms and that differential expression patterns exist between sexes and across tissues. To investigate the latter we used a new generation sequencing (NGS) technology that generates long sequencing reads with a range between 1000 to 10,000 base pairs in length. Single molecule real time (SMRT) isoform sequencing (IsoSeq) of several tissues (liver, lung, adipose, muscle, hypothalamus and testis) was carried out. Transcript sequences were used for bioinformatics analysis and isoform characterization. Given the focus of this manuscript the SMRT technology we are only presenting results obtained with the analysis of the bUTY and bUTX genes.
Improvement of the extraction of carotenoids and capsaicinoids of chili pepper native (Capsicum baccatum), assisted with cellulolytic enzymes
Authors: Gamarra Mendoza Norma Nélida , Velásquez Rodríguez Silvia Andrea , Roque Lima Blanca Lilia
Published: March 2020

The production of cellulases of Aspergillus niger ATCC 10864 was carried out by fermentation in biofilms (FB). The extracts of cellulases were used to hydrolyze the cellulose of Capsicum baccatum “escabeche chili” fruit, for this the chili fruits were dehydrated and ground to a particle size < 0.045 mm. Then dry chili: cellulase was mixed and hydrolyzed under conditions of agitation, controlled time and temperature. The medium was filtered and the supernatant of the hydrolyzed chili cake was separated, the latter was dried at 10% humidity and leached with a mixture of hexane:acetone:ethanol to extract the carotenoids and capsaicinoids, which were quantified by HPLC. The extraction yield of oleoresin was five times higher compared to the conventional method; likewise in the T8 and T5 treatments, greater extraction of carotenoids and total capsaicinoids was achieved compared to the other treatments. The hydrolytic action of the cellulases, on the molecular structures of the cellulose of the red drop chili fruit, favored greater release of the carotenoids and total capsaicinoids compared to conventional methods.
“Faça o que eu digo, não o que eu faço?” Um Estudo sobre a Transmissão Valorativa entre Pais e Filhos
Authors: Soares Ana Karla Silva , Cavalcanti Thiago Medeiros , Freire Sandra Elisa de Assis , Rezende Alessandro Teixeira , Ribeiro Maria Gabriela Costa , Gouveia Valdiney Veloso
Published: March 2020

Este estudo objetiva identificar em que medida os valores dos pai/mães e filhos estão relacionados, considerando o tipo de transmissão (direta ou indireta) e seu poder preditivo. Participaram 204 pares de pais e filhos. Dentre as crianças, a maioria era do sexo feminino (54,7%) e com idade média de 11 anos (DP = 1,01). Os pais, a maioria eram mães (69,6%), com idade média de 38 anos (DP= 7,82). Estes responderam o Questionário dos Valores Básicos correspondente ao seu grupo etário e a questões sociodemográficas. Os resultados indicaram que os valores dos filhos são influenciados mais fortemente pelos valores percebidos em seus pais do que pelos valores que os pais priorizam ou almejam para seus filhos, apresentando indicadores significativos nas seis subfunções valorativas. Conclui-se que por meio do processo de socialização, a criança apreende os valores transmitidos por seus pais a partir da observação de seus comportamentos, enfatizando que o próprio comportamento é a melhor forma para educar os filhos.
Relações entre Forças de Caráter e Autorregulação Emocional em Universitários Brasileiros
Authors: Noronha Ana Paula Porto , Batista Helder Henrique Viana
Published: March 2020

Investigar a relação entre as forças de caráter e a autorregulação emocional faz-se importante, pois os construtos podem auxiliar na diminuição de psicopatologias e contribuir para um desenvolvimento saudável. O estudo teve por objetivo analisar a predição das forças de caráter em relação à autorregulação emocional diante de eventos tristes. A amostra teve 233 universitários, com idades entre 18 e 52 anos (M= 23,20; DP= 5,588). Os participantes responderam a Escala de Forças de Caráter (EFC) e a Escala de Autorregulação Emocional-Adulto (EARE-AD). Cada fator da EARE-AD foi predito por pelo menos três forças de caráter (β entre 0,177 e 0,375). Com exceção da força espiritualidade, todas as forças se associaram significativamente com os fatores da EARE-AD (r entre 0,14 e 0,47). Os resultados parecem indicar que as forças de caráter vitalidade e autorregulação são as que mais contribuem para minimizar dificuldades emocionais. Novos estudos são sugeridos a fim de compreender alguns resultados encontrados nas forças de caráter.
Review: Does Gabapentin Relieve Opioids, Cannabis and Methamphetamines Addictions?
Authors: Quintero Garzola Gabriel Conrado
Published: March 2020

The study reviews the suitability of using Gabapentin for treating opioid, cannabis and methamphetamine use disorders. This revision consists of 61 biographical references based on a PubMed database search (January of 1983-May of 2018). Gabapentin displayed respectively 50% and 66.7% of success for treating methamphetamine dependence and opioid withdrawal symptoms. Furthermore, a few research studies have reported Gabapentin´s efficacy for alleviating cannabis dependence (two studies), and cannabis withdrawal symptoms (one study). Similarly, a single study reported Gabapentin reduction of opioid consumption during the detoxification process. Based on the revision, we can conclude that: (a) Gabapentin is useful for treating opioid withdrawal symptoms, (b) additional studies are necessary for elucidating the effectiveness of Gabapentin for treating methamphetamine dependence, cannabis dependence and its withdrawal symptoms, and (c) more studies are necessary to confirm the efficacy of Gabapentin in reducing opioid consumption during detoxification.
Encuadres mediáticos del Perdón y Reconciliación en el contexto del conflicto armado colombiano
Authors: López Wilson , Correa-Chica Andrea , Morales-Sierra María Del Pilar , Rivera-Escobar Sara , Rincón-Unigarro Camilo
Published: March 2020

Debido a su duración e intensidad, el conflicto armado colombiano puede ser analizado como un conflicto intratable. La intratabilidad involucra el desarrollo del ethos del conflicto (EDC), un conjunto de creencias sociales compartidas por la mayoría de los miembros de la sociedad, de manera que es usualmente exhibido en el discurso mediático. Este estudio describe, a través de la lexicometría unidimensional y multidimensional, cómo el edc permeó el discurso de cuatro de los principales medios de comunicación en Colombia (El Tiempo, El Espectador, Noticias Caracol, Noticias RCN); específicamente, cómo el EDC caracterizó el encuadre del perdón y la reconciliación durante el proceso de paz entre el Gobierno colombiano y las FARC-EP (2012-2017). Los resultados sugieren que el edc en Colombia se transformó con los diálogos de paz, probablemente promoviendo una orientación hacia la paz. Sin embargo, simultáneamente, algunas de las creencias del edc que contribuyen a la intratabilidad también fueron presentadas en el discurso mediático.
Dynamic processes in the phonetic system of present-day dialects of Udmurt (on the material of central dialects)
Authors: Kondratieva Natalia V. , Sokolova Olga L.
Published: March 2020

Introduction. The article deals with the dynamic processes in the phonetic system of Bol’shoi Zhuzhges dialect of Udmurt in its present state.
Materials and methods. The main source of the research is the audio materials recorded by the authors of the paper in the villages Bol’shoi Zhuzhges, Malyi Zhuzhges and Kosoevo of Uva district of the Udmurt Republic from 52 informants in five age groups: 10–18 , 18–30, 30–50, 50–70 and over 70 year old. The article employs a complex of methods is used to conduct the research: data collecting “field work” (conversation, direct questions, questionnaires, interviews, observation of speech activities, target selection); the descriptive method (observation, data comparing, generalization as well as interpretation and classification of the materials); с) comparative-historical and qualitative-statistic.
Research and Discussion. The analysis of the field materials reveals that the shift in the use of dialects in the speech of people of different age groups primarily includes the following linguistic phenomena: the use of affricates, adding non-etymological sounds in the end of words, vowel correspondence, assimilation of sounds in word stems and affixes.
Conclusion. The linguistic processes occurring in the Bol’shoi Zhuzhges develop slowly, which creates a situation when different language variants are revealed in the speech of different age groups within the same dialect. Dynamic processes in the phonetic system of the dialect are determined by intra- and extralinguistic factors.
Fresken des Schönen Stils in der Pfarrkirche von Torna (heute Turňa nad Bodvou, Slowakei) im einstigen Oberungarn
Authors: Prokopp Mária
Published: March 2020

Mural paintings of the International Gothic style in the parish church of Torna (today: Turňa nad Bodvou, Slovakia). The study gives as an introduction a short survey of the medieval history of the Hungarian Kingdom. It introduces the mural paintings of the sanctuary of the village church of Torna, which came to light between 2007 and 2014. The author emphasizes their high artistic level and presents their artistic context in Hungary. The patron of the village and the church after 1409 was Paulus Özdögei Besenyő. He was an outstanding person of the Hungarian royal court and a member of the Order of the Dragon of King Sigismund of Luxembourg. He was the donor of the painted decoration of the church of Torna. The author dates the frescoes between the years of 1410–1414.
A húgyúti fertőzések relatív gyakorisága metforminnal és SGLT2-gátlóval kezelt 2-es típusú diabetes mellitusban szenvedő betegekben. Hálózati metaanalízis
Authors: Merész Gergő , Szabó Szilvia , Dóczy Veronika , Hölgyesi Áron , Szakács Zsolt
Published: March 2020

Absztrakt:

Bevezetés és célkitűzés: A jelen kutatás célja, hogy
szisztematikus irodalomkeresésre épülő hálózati metaanalízis segítségével
összehasonlítsa a 2-es típusú cukorbetegség terápiájában alkalmazott,
metforminnal kombinált nátrium-glükóz kotranszporter-2 (SGLT2)-gátlókat a
húgyúti fertőzések kialakulási kockázatának vizsgálatán keresztül.
Módszer: A MEDLINE és EMBASE adatbázisokban történt
irodalomkeresés alapján beválogatott randomizált, kontrollos klinikai
vizsgálatok húgyúti fertőzések gyakoriságára vonatkozó eredményeit hálózati
metaanalízis segítségével foglaltuk össze, melyben a közös komparátor a
placebóval kombinált vagy monoterápiaként adott metformin volt.
Eredmények: Az irodalomkeresés során 10 165 hivatkozást
azonosítottunk, s ezek közül 10 közlemény eredményeit tartalmazza a hálózati
metaanalízis, amely alapján a húgyúti fertőzések kockázata a metforminnal
kombinált, kis dózisú ertugliflozin mellett számszerűleg alacsonyabb volt a
többi SGLT2-gátlóhoz képest (ertugliflozin, 5 mg vs.
empagliflozin, 10 mg: RR = 0,606, 95%-os CrI: 0,264–1,415; ertugliflozin, 5 mg
vs. dapagliflozin, 10 mg: RR = 0,853, 95%-os CrI:
0,301–2,285). Az empagliflozin 25 mg-os dózisa mellett a húgyúti fertőzés
kockázata számszerűleg alacsonyabbnak adódott az ertugliflozin 15 mg-os (RR =
0,745, 95%-os CrI: 0,330–1,610), valamint a dapagliflozin 10 mg-os (RR = 0,680,
95%-os CrI: 0,337–1,289) dózisához képest. A hatóanyagok, illetve a dózisok
közötti eltérés a húgyúti fertőzések tekintetében nem bizonyult statisztikailag
szignifikánsnak. A metaregressziós elemzések alapján a kiindulási éhomi
plazmavércukorszint statisztikailag szignifikáns, pozitív irányú összefüggést
mutatott a húgyúti fertőzések relatív gyakoriságával (β = 0,785, 95%-os CrI:
0,062–1,587). Következtetések: A húgyúti fertőzések relatív
gyakoriságát vizsgálva nem igazolható statisztikailag szignifikáns különbség a
vizsgált, metforminnal kombinált SGLT2-gátló kezelések között. A jelen tanulmány
példaként szolgálhat arra, hogy szabadon rendelkezésre álló eszközök
felhasználásával lebonyolítható egy hálózati metaanalízis, amely az egészségügyi
technológiák relatív hatásosságának, biztonságosságának értékeléséhez gyakran
nélkülözhetetlen. Orv Hetil. 2020; 161(13): 491–501.
Computer-Assisted Language Learning at the University of Dundee
Authors: Lewis Derek R.
Published: March 2020

This essay is intended to give a brief overview of activities in the field of Computer Assisted Language Learning in which the Modern Languages Department of the University of Dundee (Scotland) is involved.
PROGRAMMING FOR MISSPELLED EXTENDED INPUT
Authors: Soemarmo Marmo
Published: March 2020

Several means of providing students with informative feedback are presented in this article. They are incorporated into three samplelessons that are written in APPLESOFT BASIC. These sample lessons can be used to create supplementary CAI materials.Lesson LIM-LEN MISSPELL indicates the length of the expected input and disallows the inputting of a longer string. Feedback is in the form of reproducing the correct part of the input. Reinputting must be done by retyping the answer. Lesson RESPELL is very similar to LIM-LEN MISSPELL but reinputting of a longer string than the expected length is not prevented. However, reinputting is simplified by allowing students to screen copy the correct portion of the input.Program MISSPELLING gives specific feedback on misspelling of the input, whether the input is (a) one letter short, (b) contains one misspelled letter, (c) contains two letters in reversed order, or (d) contains the correct rootstem but the form is incorrect, with an indication on whether the students should check the prefix, suffix or both.In addition to the standard maximization of user friendliness and crash prevention, all three allow extended input. Input that contains commas, quotations, colons, etc. will not result in ?EXTRA IGNORED messages.
COURSEWARE - SOFTWARE INTERFACES
Authors: Paramskas D. M.
Published: March 2020

When designing a free-form remedial/tutorial program for second language learning, several principles are essential to insure pedagogically sound courseware. These include adaptability in terms of instructor requirements and user population needs; user friendliness to reduce machine-induced phobias and compensate for mechanical ignorance; sophistication in error analysis through extensive branching in order to produce comments which will help the user to learn through his/her errors; and flexibility, which gives the user control over both the content and the pace of learning. There are some disadvantages to such a program, but newer projects aim to overcome these disadvantages by allowing the individual instructor more freedom in creating materials for specific needs. Finally, evaluation through statistical records is discussed as a point of contention.
THE INTEGRATION OF CALL MATERIALS INTO THE OVERALL CURRICULUM
Authors: Rüschoff Bernd
Published: March 2020

The subject of CALL has only recently been introduced to language teachers in West Germany. While in other European countries many institutions are involved in projects dealing with the use of computers in language learning, the Audiovisual Media Centre (AVMZ) at the University of Wuppertal is one of the few places in this country investigating various approaches to CALL.Among other aspects of computers and language learning, our research project focuses on the problem of linking computerbased materials with the teaching unit as a whole in a meaningful way. This article describes the kin of programs developed at the AVMZ as well as one of the methods we are experimenting with to achieve this objective.
Counting Demons and Devas
Authors: Romain William F.
Published: March 2020

In the article referenced below and published earlier in Journal of Skyscape Archaeology 4(2), discussion was presented concerning the bas-relief at Angkor Wat known as the "Churning of the Ocean of Milk". The present paper clarifies certain points in the original discussion and provides additional details concerning the posited day-count between equinox and solstices as represented in the relief.
Keith Ray and Julian Thomas, 'Neolithic Britain: The Transformation of Social Worlds'
Authors: O’Donnell Ingrid
Published: March 2020

Keith Ray and Julian Thomas, Neolithic Britain: The Transformation of Social Worlds, Oxford: Oxford University Press, 2018. Hardback, 416 pages. ISBN: 978-0-19-882389-6. £30.
Gyula Priskin, 'The Ancient Egyptian Book of the Moon: Coffin Texts Spells'
Authors: Brady Bernadette
Published: March 2020

Gyula Priskin, The Ancient Egyptian Book of the Moon: Coffin Texts Spells. 154–160. Archaeopress Egyptology 22. Oxford: Archaeopress, 2019. Paperback. ii+254 pp., 4 tables, 1 figure. ISBN: 9781789691986. £30.00.
Stability analysis of twin circular tunnels using shear strength reduction method
Authors: Shiau J. , Al-Asadi F.
Published: March 2020

This paper investigates the face stability of twin circular tunnels horizontally aligned in cohesive undrained soil under plane strain conditions. The shear strength reduction method in the two-dimensional finite-element limit analysis programme is used to obtain rigorous upper and lower bounds of the factor of safety (FoS) for various depth ratios (C/D) and centre-to-centre spacing ratios (S/D) between the tunnels. Since the undrained shear strength is not a function of the mean normal stress, stability results are independent of loading directions. Therefore, the stability (in collapse or blowout) for this problem is well expressed by using Broms and Bennermarks’ original stability number N = (σs + γH − σt)/Su. The variations of the FoS have been presented for different combinations of stability numbers (N) and geometries (C/D and S/D). The FoS and the stability number results are compared and validated by using the finite-difference method as well as other existing solutions available in the literature. The results from this study are summarised in stability charts for use by designers and practising engineers.
La zona de posibilidades en el proceso de aprendiencia del residente digital: Un análisis cualitativo en la Red de experiencias Matemáticas de Norte de Santander
Authors: Gómez-Valderrama Carlos , Hernández-Suárez César , Prada-Nuñez Raul
Published: March 2020

Objetivo: Identificar, determinar y describir la zona de posibilidades en el estar-en-proceso-de-aprender del residente digital, según mapeo visitante/residente, para mejorar la práctica de construcción de la Red Personal de Aprendizaje. Método: Se trata de una investigación cualitativa, cuyos sujetos de investigación son profesores que integran la Red de Experiencias Matemáticas de Norte de Santander, Colombia. La información se recolectó a través de grupos de discusión en los foros temáticos. Resultados: Se muestra la zona de posibilidades en el proceso de aprendiencia del residente digital como resultado de la investigación. Discusión y Conclusiones: Se concluyó que la zona de posibilidades puede ser una zona difusa para las personas que no tienen una concepción clara de lo que representa la Red Personal de Aprendizaje, para beneficiarse de la inteligencia colectiva de este, y, por ende, precisar nuevos nodos de saberes
Financiamiento y desarrollo empresarial en las MYPES residentes en el parque industrial de Huaycán
Authors: Tanta Espinoza Ingrid Lizeth , Vilca Coaquira Abigail Elizabeth , Luy Medina Gloria Ivon
Published: March 2020

La presente investigación analiza la relación entre el financiamiento y desarrollo empresarial de las MYPES (Micro y Pequeñas Empresas) residentes en la zona industrial de Huaycán, ciudad del distrito de Ate-Vitarte, Lima. El estudio es de tipo descriptivo correlacional con un diseño no experimental y de corte transversal. La población en estudio estuvo formada por 60 MYPES en el mencionado lugar. A fin de medir el financiamiento interno se utilizó un cuestionario elaborado por Márquez (2007). Para medir el financiamiento externo se utilizó un cuestionario creado por Cornejo y Galicia (2010); el cuestionario de desarrollo empresarial fue elaborado por García (2003). Su fiabilidad se verificó por el alfa de Cronbach, que para el financiamiento obtuvo 0.95 y para el desarrollo empresarial 0.840. Los resultados de Rho de Spearman  ρ= 0.329,  p= 0.036 permite concluir que el financiamiento tiene una relación significativa directa sobre el desarrollo empresarial. Entonces, a mayor financiamiento las MYPES tendrán mayor desarrollo empresarial que les permitirá tener un desempeño óptimo en sus actividades que involucran a gran parte de la población, permitiéndoles tener una oportunidad de negocio y empleo, mejorando de esta manera la economía de sus familias, a fin de propiciar la reducción de pobreza en el país.
Efectividad del consumo de la hoja de guayaba sobre los niveles de glucosa en ratas diabéticas tipo 2
Authors: Díaz Correa Betty Esther , Chinchay Quito Marco Antonio
Published: March 2020

Este trabajo de investigación tiene como objetivo evaluar la efectividad de la hoja de guayaba en polvo sobre los niveles de glucemia en ratas (Sprague - Dawley) inducidas a diabetes mellitus tipo 2 (DM2) con el fármaco estreptozotocina (STZ). Esta investigación tiene un enfoque cuantitativo, de diseño experimental, explicativo y de corte longitudinal. La muestra estuvo conformada por 40 ratas macho de la cepa Sprague –Dawley de 5 semanas, distribuidos en 3 grupos de tratamiento: grupo control no diabético, grupo experimental 2 y grupo experimental 3 respectivamente. Para el proceso de inducción de diabetes tipo 2, las ratas recibieron una cantidad de fructuosa al 10% por dos semanas, seguidamente se les administró el fármaco estreptozotocina (STZ) por vía intraperitoneal (50mg/kg). Los grupos experimentales fueron alimentados por una sonda orogástrica, con una dosis de 500mg/Kg y 1000mg/Kg de hoja de guayaba en polvo, para los grupos experimentales que comprende el grupo 2 y el grupo 3, respectivamente, por un periodo de 3 semanas. Al finalizar el tratamiento, los grupos experimentales mostraron una disminución significativa de glicemia y un descenso de peso corporal. Este estudio concluye que la dosis de 1000mg/Kg de la hoja de guayaba en polvo, presenta mayor disminución de glicemia, luego de su consumo.
Transformações urbanas em Baku no século XXI
Authors: Imbronito Maria Isabel , De Paula Danilo Firbida
Published: March 2020

Este trabalho pretende fornecer elementos para o entendimento das transformações urbanas recentes de Baku, capital do Azerbaijão, apoiando-se nas circunstâncias históricas e atuais do Azerbaijão, e no mapeamento das intervenções, organizadas de modo a traçar sobre a cidade arcos de desenvolvimento urbano que foram identificados na pesquisa.
Diagnóstico e Propostas para a Gestão de Resíduos Sólidos da Construção Civil, Volumosos e Lenhosos Urbanos no Município de Jales - SP
Authors: Balbino Gustavo Alves , Vanzela Luiz Sergio , Tagliaferro Evandro Roberto , Mansano Cleber Fernando Menegasso
Published: March 2020

Um dos maiores desafios atuais das gestões municipais está no gerenciamento de resíduos sólidos, sobretudo os resíduos sólidos da construção civil, volumosos e lenhosos urbanos (RSCCVLU), que normalmente não possuem uma regulamentação de cobrança. Por isso, utilizando-se de método dedutivo de abordagem qualitativa, de natureza exploratória combinado com a pesquisa bibliográfica, realizou-se o diagnóstico da situação da gestão de RSCCVLU no município de Jales - SP e elaborou propostas legais e sustentáveis para solucionar as deficiências no gerenciamento. A pesquisa foi desenvolvida no período de julho de 2018 a outubro de 2019, no qual avaliaram-se os seguintes aspectos: a evolução da gestão político-administrativa de RSCCVLU e os impactos da concessão do gerenciamento ao setor privado. Em seguida, a partir do levantamento das deficiências, elaboraram-se propostas para a melhoria do sistema de gestão. Observou-se que houve uma evolução na gestão de RSCCVLU e melhorias com a concessão do gerenciamento a iniciativa privada. Com base nas deficiências levantadas, sugere-se para o Município de Jales - SP, as seguintes propostas para a melhoria no gerenciamento de resíduos sólidos da construção civil, volumosos e lenhosos urbanos: atualização real e participativa do Plano Municipal de Gestão Integrada de Resíduos Sólidos (2021-2024), quantidade de resíduos gerados, previsão orçamentária para o gerenciamento de RSCCVLU, regulamentação do sistema de cobrança, criação de sistema de cálculo para tarifa de RSCCVLU e destinação correta de recursos da contribuição tarifária.
Distinção de Modos de Transporte em Áreas Urbanas com base no uso de Protótipo de Receptor GNSS
Authors: Botion Neri Thiago , Louro Thiago Vinicius , Barbosa Fontenele Heliana , Prado da Silva Junior Carlos Alberto
Published: March 2020

Com o processo de urbanização pelo qual o mundo vem passando nas últimas décadas, os problemas inerentes às cidades tornam-se cada vez mais sérios. Assim, o planejamento de transporte precisa ser feito com maior precisão, em intervalos de tempo mais curtos e com custos mais acessíveis. Neste estudo, foi apresentado um processo para caracterizar e diferenciar viagens por diferentes modos de transporte através de dados brutos do receptor GNSS. Para a coleta de dados de viagem, foi utilizado um protótipo de receptor GNSS desenvolvido com a plataforma Arduino. Foram coletados dados de deslocamentos, realizados por quatro modos de transporte. A análise dos dados de velocidade e aceleração, permitiu diferenciar os deslocamentos por modos não motorizados e motorizados, além de, diferenciar as viagens realizadas por meio de caminhada e bicicleta. No entanto, somente com a ajuda de um SIG foi possível diferenciar viagens por carro e ônibus.
Mask Building Idea v1
Authors: Wells Erica
Published: March 2020

Our limited findings: This “DIY folding mask” tries to replicate some of the benefits of a n95 mask. It has been saccharin tested by several nurses and an NP. I cannot say these are as effective as a factory n95 mask because of course a real one would be better. But I tested it against a CDC recommended bandana and scarf and it seems to out perform them. It also seems to outperform the surgical mask.
10X TBS Buffer v1
Authors: Drown Bryon
Published: March 2020

Tris buffered saline (TBS) is a commonly used buffer with a wide range of applications in biochemistry. It is often more convenient to prepare a 10X solution so that additional components can be added when preparing the buffer on demand.
Viral Sequencing, from Gunk to Graph (Two-step, strand-switching) v2
Authors: A Eccles David
Published: March 2020

This is a fast "gunk to graph" protocol for analysing viral RNA from nasopharyngeal swabs. The approach involves swab lysis and inactivation at the point of sampling, uses a cellulose binding / wash protocol to reduce extraction cost, incorporates sample-specific barcodes during first-strand synthesis, nanopore rapid-attachment primers during PCR amplification, and nanopore sequencing with parallel RAMPART analysis for fast assembly and phylogenetics.
Violência obstétrica e os direitos da parturiente: o olhar do Poder Judiciário brasileiro
Authors: Brito Cecília Maria Costa de , Oliveira Ana Carolina Gondim de A. , Costa Ana Paula Correia de Albuquerque
Published: March 2020

Objective: the current study investigates the obstetric violence through judged cases, under the Judiciary’s perspective about the theme. Methodology: it is a literature review study, whose research happened from June of 2019 to January of 2020. For contextualization and analysis of the problem, a bibliographic search was performed through indexed scientific sources in Bireme, Latindex, and Scielo database. The judges analyzed were selected in the website Jusbrasil, whose sampling was made through the results of search by the term obstetric violence. Five cases were selected as samples to the development of the article. Results: obstetric violence can be considered a type of gender, symbolic, and institutional violence. As it is rooted in the feminine everyday life, in many situations, it is naturalized. However, the increasing access to information, among other facts, has been causing a change in the attitude, proved through the growth of judicial complaints and demands. However, from the examination of the judges was possible to identify the lack of knowledge from magistrates about the theme, which results, in some occasions, in the mitigation of the rights by the own Judiciary Branch. Conclusion: even in spite of the debate about violence against women, obstetric care is still little discussed and greatly invisibilized. It is manifested in extremely delicate phases, pregnancy and childbirth, mitigating not only the rights and dignity of parturients, but, equally, of the unborn child. Moreover, the highest incidence of this type of violence are still the environment of public hospitals, which users are, mostly, black and poor.
Mediação de conflitos na gestão da saúde (médica, clínica e hospitalar): humanização do direito médico
Authors: Nascimento Dulce Maria Martins do
Published: March 2020

Objective: to demonstrate that the conflict mediation process presents itself as an adequate response in the prevention, management and resolution of differences, where there are ongoing relationships and the interest in building effective, global and lasting solutions. Methodology: the present work is based on a bibliographic review and on the author's professional experience, through her interventions and practical experiences, with more than 5,000 hours of experience in mediation alone. Results: most of the conflicts between the different health subcultures - medical, nursing, administrative, patient and family relations, as well as, more recently, information technology and robotics in health - are directly related to different forms of work, authority and legitimacy, understood as divergent and mostly understood as incompatible and irreconcilable. Likewise, it is essential to know and incorporate consensual, voluntary and confidential dialogue and negotiation processes in the organization, such as mediation, facilitated by an impartial third party, with no decision or judgment power. It is confirmed the need for health leaders to know how to deal with the complexity of conflicts, which remain between the different subcultures. Organizations and managers who use consensual processes in a technical way enhance positive experiences, as well as improve quality indicators in the organizational social environment. Conclusion: it is expected that medical, clinical and hospital managers develop competences for the prevention, management and consensual resolution of conflicts, being necessary to develop and deepen the knowledge  of the mediation process.
Danos causados por medicamentos: responsabilidade civil do produtor no âmbito da legislação portuguesa
Authors: Martins Mickael
Published: March 2020

Objective: to analyze, on the one hand, the legal regime applicable in case of damages caused by medicines and, on the other hand, the difficulties that arise with the (in) sufficiencies of that same regime. Methodology: a bibliographic analysis was carried out on this topic. Results: although the legal regime in force proves to be adequate to most products, the same cannot be said when a medicine is concerned, taking into account its own characteristics and the interaction with the human body that immediately establishes itself. Conclusion: as in other European legal systems, it could be envisaged to legislate specifically on civil liability arising from damage caused by drugs, as is the case in Germany, or to enshrine some regime differences when a drug is concerned, as happened in Spain.
En marzo de 2020: luchar contra la enfermedad, superar la desesperación, pensar en la salud
Authors: Curado Manuel , Rodrigues João Vaz , Pereira André Dias
Published: March 2020

Editorial of the Ibero-American Health Law Journal, vol. 9, n.1
Educational Memory of Chinese Female Intellectuals in Early Twentieth Century
Authors: Menga Guo
Published: March 2020

Educational Memory of Chinese Female Intellectuals in Early Twentieth Century describes the campus life, teacher-student interaction, academic career, and ideological change of the first generation of female intellectuals trained in higher education in China as the Chinese society changed in the early 20th century. Using the research methods of life history, oral history, and history of mentalities, the author reveals the special experiences and ideological journeys of Chinese female intellectuals by the literature works of three first-generation Chinese female intellectuals and other people's interpretations and commentary on their works. It also analyzes the relationship between many factors such as society, academia and education, especially higher education, and female intellectuals.
O NARRADOR FINGIDOR EM O MAL DE MONTANO, DE ENRIQUE VILA-MATAS
Authors: Arruda de Souza Rosana
Published: March 2020

Em tempos de avulto sobre a querela do autor, ou seja, sobre as teorias literárias que promulgam ora a morte do autor, ora o seu retorno, propomos, neste trabalho, um contracaminho. Tendo por objeto o romance O mal de Montano, objetivamos colocar, no centro do palco, o narrador, ao invés do autor, e articular a possibilidade daquele ser um fingidor, de quando mobiliza as peças do jogo e se esconde atrás de várias máscaras. Para tanto, dialogaremos com a teoria iseriana, a respeito da recepção e dos atos de fingir, e com autores que possam contribuir com a discussão aqui proposta.
A leitura de literatura sul-rio-grandense contemporânea no contexto universitário
Authors: Da Silva Almeida Magali Lippert , Castello João Victor Martins , Gomes Júlia De Andrade
Published: March 2020

A questão que pretendemos responder neste artigo é se a literatura sul-rio-grandense contemporânea é lida pelos leitores gaúchos. Para isso, foram analisadas e discutidas as respostas a um questionário que visava delimitar o horizonte de leitura do entrevistado, verificando sua familiaridade com a literatura gaúcha contemporânea. O questionário foi aplicado, aleatoriamente, no Campus do Vale, da Universidade Federal do Rio Grande do Sul. Observa-se, nas respostas ao instrumento de coleta de dados, a presença majoritária de best-sellers e cânones internacionais entre as leituras feitas pelos participantes e pouca presença da literatura sul-rio-grandense publicada atualmente. Disso conclui-se que o mercado literário internacional vem ofuscando expressões literárias locais no Estado, e que, cada vez mais, há um afastamento entre obra gaúcha e leitor gaúcho.
Antisocial Personality Disorder in Adolescence: Methodology and Diagnostics
Authors: Syrokvashina K.V. , Dozortseva E.G.
Published: March 2020

The paper describes the issues in conceptualization and diagnostics of antisocial personality disorder in adolescents and youths. Modern interpretations of the antisocial personality disorder and psychopathy categories are presented in two competing approaches headed by R. Hare and D. Cooke. The application of these diagnoses to adolescents remains problematic, however, it is possible to single out certain predictors indicating potential development of antisocial personality disorder in the future. The methods of diagnostics of the antisocial personality disorder and corresponding individual traits in adolescents present a special problem. Further development of this research area will contribute to the forming of the theoretical grounds, methods, and inventories, as well as the practice of diagnostics, prevention and correction of antisocial personality disorder in adolescents and youths.
Maladaptive Personality Traits and Psychopathological Symptoms in Individuals with the First Suicidal Attempt and with Chronic Suicidal Behavior
Authors: Kholmogorova A.B. , Subotich M.I. , Korkh M.P. , Rakhmanina A.A. , Bykova M.S.
Published: March 2020

The paper compares the severity of maladaptive personality traits and psychopathological symptoms in patients with primary and repeated suicide attempts. The study involved patients of the somatopsychiatric department of the Sklifosovsky Research Institute of Emergency Care (N=61), who committed the first suicide attempt (n=31) or a repeated attempt (n=30). The results of the study did not reveal differences between the two groups in the severity of symptoms of social anxiety, depression and trait anxiety. However, indicators of such maladaptive personality traits as perfectionism and hypersensitive narcissism were significantly higher in the group of patients with a repeated suicide attempt. This group also manifested higher rates of the severity of borderline personality disorder traits and significant correlations between measures of psychopathology and maladaptive personality traits listed above. Conclusion: timely diagnostics of maladaptive traits and psychotherapy targeting socially prescribed perfectionism, hypersensitive narcissism, and borderline personality features after the first suicide attempt is necessary to prevent repeated ones.
Energy-momentum puzzle in a bianchi-type ıı universe with f(T) gravity
Authors: KORUNUR Murat
Published: March 2020

The energy-momentum localization problem, which was attemted by Einstein himself for the first time, has been continued to the present day. Recently, new prescription obtained by modifying the torsion theory and these results shed light on the solution of the energy momentum localisation problem. Focusing this purpose, we consider a Locally Rotationally Symmetric Bianchi Type-II model in the teleparallel framework and calculate the modified energy and momentum density for the general case. We also obtain the energy and momentum density for some special cases of the modified theory and compare our results with previous work in the literature.
Classification of the placement success in the undergraduate placement examination according to decision trees with bagging and boosting methods
Authors: TUĞ KAROĞLU Tuğba , OKUT Hayrettin
Published: March 2020

The purpose of this study is to classify the data set which is created by taking students who placed to universities from 81 provinces, in accordance with Undergraduate Placement Examination between the years 2010-2013 in Turkey, with Bagging and Boosting methods which are Ensemble algorithms. The data set which is used in the study was taken from the archives of Turk-Stat. (Turkish Statistical Institute) and OSYM (Assessment, Selection and Placement Center) and MATLAB statistical software program was used. In order to evaluate Bagging and Boosting classification performances better, the success rates of the students were grouped into two groups. According to this, the provinces that were above the average were coded as 1, and the provinces below the average were coded as 0 and dependent variables were created. The Bagging and Boosting ensemble algorithms were run accordingly. In order to evaluate the prediction abilities of the Bagging and Boosting algorithms, the data set was divided into training and testing. For this purpose, while the data between 2010-2012 yearrs were used as training data, the data of the year 2013 were used as testing data. Accuracy, precision, recall and f-measure were used to demonstrate the performance of the methods in the study. As a result, the performance in consequence of "Bagging” and “Boosting” methods were compared. According to this; it was determined that in all performance measure marginally “Boosting” method produced better results than the “Bagging” method.
Comparison of Remote Sensing Classification Techniques for Water Body Detection: A Case Study in Atikhisar Dam Lake (Çanakkale)
Authors: ÖZELKAN Emre
Published: March 2020

Water resources management is
one of the most important issues of today. Satellite remote sensing have been
successfully used to detect the presence of water bodies. In this study, four
remote sensing methods: (1) normalized difference water index (NDWI), (2)
support vector machine (SVM), (3) geographic object-based image analysis
(GEOBIA) and (4) NDWI supported GEOBIA (GEOBIA_NDWI) were examined for water
body area detection. For this purpose, Atikhisar Dam Lake, the only water
source of Çanakkale central district of Turkey was selected as study area. As
remote sensing data nine multitemporal Landsat-8 Operational Land Imager (OLI)
multispectral satellite images between 2013 and 2017 were used. For the
accuracy assessment, area values extracted from the used methods were tested
with in-situ measurement lake area values. The main issues discussed in this
study can be specified as follows: (i) Is pixel-based classification SVM or
object-based image classification GEOBIA more successful in the water body
detection?, (ii) Are the image classification methods (SVM and GEOBIA) or the
water index (NDWI) more successful in the water body detection? and (iii) What
is the contribution of NDWI to GEOBIA_NDWI (GEOBIA_NDWI) classification in the
water body detection? The results show that meteorological factors and irrigation
were influential in lake area variations. NDWI was found to be superior to
other methods in determining water body and allowed for better detection of the
lake boundary. Additionally, NDWI made a better separation of the land cover
classes adjacent to water at the border. The object based GEOBIA was better
than the pixel based SVM for distinguishing water and other land cover classes
adjacent to border. GEOBIA_NDWI lake area results were more accurate than the
standard object-based classification. Mixed pixels out of the lake area was
determined less in the NDWI and GEOBIA_NDWI results.
An integrated approach by fmea & fuzzy prioritization method at pharmaceutical ındustry quality control
Authors: YÜCENUR G.nilay , ÇATALTEPE Seren , SAKİN İrem
Published: March 2020

Protecting public health, taking preventive measures and ensuring recovery in case of any disease are conditions for creating a healthy life. In order to create this life, the manufacturing process of the pharmaceutical industry needs to be formed carefully. In this study there is a risk analysis application into operational processes of a pharmaceutical company. In application study, operational processes of sample company were examined and analyzed from October to May. Within the scope of the study, a two-stage approach was proposed in the analysis of the data obtained. In the first phase, fishbone analysis was carried out to determine the risks in the operational processes and the potential risks in two separate production lines were determined. In the second stage, the risk prioritization method was used and risk priority numbers (RPN) were calculated for all risks. In all these analysis, more realistic and valid results were obtained with the usage of fuzzy logic and the calculations of RPNs were made more objective and independent from analysts. After the determination of RPNs, precautions were suggested for high risky failures. Following the implementation of precautions, new RPNs were calculated for all failures. The old and the new RPNs were compared for all risky failures and all precautions were examined with their impacts on the process. As a result, all examined failures’ risk prioritization numbers were reduced in the ratio between 72% and 90%, the operational processes were improved.
On complex gaussian jacobsthal and jacobsthal-lucas quaternions
Authors: ARSLAN Hasan
Published: March 2020

The main aim of this work is to introduce the complex Gaussian Jacobsthal and Jacobsthal-Lucas quaternions and investigate their structures. We obtain the recurrence relations, Binet formulas and generating functions for these quaternions. We also give their Cassini identities by using Binet formulas. Furthermore, we prove some results for these quaternions such as summation formulas.