bluuebunny/crossref_metadata_2025 huggingface dataset:
SYNTHESIS AND PROPERTIES OF SELENIUM NANOPARTICLES IN NATURAL POLYSACCHARIDES MATRIX
Authors: Panov Denis Aleksandrovich , Katsev Andrew Moiseevich , Omel'chenko Aleksandr Vladimirovich
Published: April 2022

Selenium nanoparticles were obtained by reduction of sodium selenite in aqueous solutions of nonstoichiometric alginate-chitosan polyelectrolyte complexes. Amorphous red nanosized selenium, formed as a result of the reaction, were characterized by maximum absorption at 256 nm. The process of formation and morphological characteristics of them were studied at different mass ratio of the components in the selenium-polysaccharide complex (in the range from 0.01 to 0.10). The morphological, dimensional, and spectral characteristics of obtained selenium nanoparticles were determined by transmission electron microscopy (TEM) and UV spectroscopy. The sample of nanoselenium was shown to consist of single nanoparticles, mostly spherical or partially elongated shapes, with an average size of 40 nm. The replacement of alginate (no more than 10%) with chitosan causes a significant increase in the stability of selenium nanoparticles, preventing them against aggregation and color change for three months. The biotoxicity of the synthesized nanoselenium was studied using Aliivibrio fischeri F1 bioluminescent assay. Selenium nanosamples were found to have no any inhibitory effect on bacterial bioluminescence and growth and thus have neither acute nor chronic biotoxicity. On contrary, sodium selenite, used for a comparison, decreased the bioluminescence of A. fischeri F1 at concentrations more than 100 mg/L. The values of NA2SeO3 half maximal effective concentration (EC50) were measured to be 420-820 mg/L at 15-60 minutes of incubation. Chronic biotoxicity of sodium selenite was manifested at concentrations more than 30 mg/L, and at 300 mg/L and higher led to a complete suppression of A. fischeri F1 growth and bioluminescence. Experimental study of biological properties of obtained selenium nanoparticles revealed an increase in seed germination and vigor of pea (Pisum sativum L.) of Madonna variety and barley (Hordeum vulgare L.) of Kuzen variety, as well as an increase in the dry matter mass of their roots and aerial parts. A high activity of growth processes for the studied crops was noted at a nanoselenium concentration of 20 mg/l.
Verificação da relação IRI e BBI na avaliação da irregularidade longitudinal de pavimentos aeroportuários
Authors: Da Silva Sousa Elisa , De Sousa Carneiro Rayssa , Lacerda de Oliveira Francisco Heber
Published: April 2022

A irregularidade longitudinal em Pistas de Pouso e Decolagem (PPD) é frequentemente monitorada por meio do International Roughness Index (IRI), índice desenvolvido para avaliação de rodovias. Com o propósito de melhor abordar as particularidades dos pavimentos aeroportuários, foi desenvolvido um método específico para as PPD, o denominado Boeing Bump Index (BBI). Este estudo busca verificar a relação existente entre o IRI e o BBI, a partir dos parâmetros de valor médio e crítico, obtidos pelo software ProFAA, comparando diferentes abordagens. Neste artigo, verificou-se que as maiores correlações foram observadas entre o IRI e BBI críticos. Além disso, essa correlação mostrou-se maior nas análises do primeiro terço de pista, com 58% das pistas apresentando R² maior que 0,70. Sendo assim, com base no conjunto de dados analisados, verifica-se que existe uma correlação significativa entre o IRI e o BBI apenas quando associados aos valores críticos.
Caso Clínico: Útero de Couvelaire, la importancia de una identificación temprana
Authors: Urgiles Barahona María José , López Macas Mariuxy del Rocío , Urgilés Barahona Cristina Elisabeth
Published: April 2022

BACKGROUND: Couvelaire Uterus or uteroplacental apoplexy is the blood extravasation to the uterine musculature and deep serosa, as a rare complication of severe forms of placental abruption. It is an infrequent syndrome, but has a rapid onset, that requires immediate attention in order to avoid maternal and fetal complications. CASE REPORT: A 33-year-old female patient, 38.4 weeks pregnant, calculated by LMP. She sought attention in a primary care health center, for a 12-hour history of uterine contraction-type abdominal pain, where controls were indicated every 4 hours. Approximately 13 hours later, in the last control, no fetal movements or heartbeat were evident, the mother had 3 cm of dilation and 80% cervical effacement, so she was transferred to a third level health care center. Upon admission, fetal death and presumptive diagnosis of PPD were confirmed, so it was decide to terminate the pregnancy immediately by cesarean section. CLINICAL COURSE: During the surgical procedure, the 2 500 grams stillborn was extracted, the uterus was macroscopically infiltrated with blood, compromising 100% of the tissue, as well as the wide ligament and the right ovary; uterine tone wasn’t achieved, Couvelaire Uterus was diagnosed and a hysterectomy was performed. During the surgical procedure the patient developed hypovolemic shock; she was stabilized with infusion of fluids, colloids, and blood components. She remained in the intensive care unit for 2 days and reached hemodynamic recovery. She developed high blood pressure that responded to nifedipine(10 mg/ 8 hours) administration. She was discharged, being stable, with hypotensive treatment. CONCLUSION: Couvelaire Uterus is a rare pathology that increases the risk of maternal complications and fetal death. The timely identification of premature placental abruption clinical signs decreases the probability to develop this pathology and increases the possibility of an optimal treatment.
Ventilación con liberación de presión en las vías respiratorias (APRV): un enfoque para su uso correcto
Authors: Guamán Crespo John Oswaldo , Ojeda Izquierdo Edgar Andrés , Monares Zepeda Enrique
Published: April 2022

The correct use of APRV provides alveolar opening for most of the respiratory cycle, reducing its movements and pulmonary stress, which reduces the mechanical power and the risk of damage caused by invasive mechanical ventilation. From its beginnings, to the present, ventilation with APRV has been criticized due to the results obtained in several research. Analyzing them, it can be seen that the application of this ventilation mode is not always adequate, interfering with its very objective. In this short-review, we describe the physiological foundations and the correct way to use APRV in intensive care patients, as well as the evidence that justifies the advantages and disadvantages of APVR.
Crecimiento y Desarrollo Craneofacial: Mini-review de la Teoría de Servosistema
Authors: Yánez Zurita Christian , Bacuilima Chimbo Jéssica
Published: April 2022

Craniofacial growth is a process that begins in utero and lasts until the individual reaches maturity. Despite the fact that a consensus has been sought regarding the theories that explain how this process occurs, it hasn’t been possible to establish a validated and accepted hypothesis by the entire scientific community. It is important to understand the mechanisms by which the head and skull reach complete development, since this could determine the cause of facial malformations and dental anomalies, such as malocclusions. Among the postulated theories, Alexandre Petkovic’s Servosystem Theory stands out, and remains under considerations now a days. Unlike other postulates, the so-called cybernetic theory of growth establishes the role played by hormonal and mechanical factors over genetic activity. The aim of this review is to assess the concepts and fundamentals of the Servosystem Theory and how it explains craniofacial growth
A Simple Proof of Dvoretzky-Type Theorem for Hausdorff Dimension in Doubling Spaces
Authors: Mendel Manor
Published: April 2022

The ultrametric skeleton theorem [Mendel, Naor 2013] implies, among other things, the following nonlinear Dvoretzky-type theorem for Hausdorff dimension: For any 0 < β < α, any compact metric space X of Hausdorff dimension α contains a subset which is biLipschitz equivalent to an ultrametric and has Hausdorff dimension at least β. In this note we present a simple proof of the ultrametric skeleton theorem in doubling spaces using Bartal’s Ramsey decompositions [Bartal 2021]. The same general approach is also used to answer a question of Zindulka [Zindulka 2020] about the existence of “nearly ultrametric” subsets of compact spaces having full Hausdorff dimension.
The effect of metformin on the metabolism of human vascular smooth muscle cells in high glucose conditions
Authors: Soleimani Ali Akbar , Abkenar Borhan Rahimi , Shokri Nafiseh , Ghasempour Ghasem , Najafi Mohammad
Published: April 2022

Objectives

Metformin is widely used in type 2 diabetic patients as an antihyperglycemic drug. The aim of this study was to investigate the effect of metformin on the metabolism of vascular smooth muscle cells in high glucose conditions.

Materials and methods

The vascular smooth muscle cells were cultured in DMEM F12 containing glucose as high as 25 mM. The preconditioned cells were then treated with metformin in doses of 1, 5, and 7 mM for 24 h. MTT method was used to determine cell viability. Biochemical parameters including lactate, glucose, total protein, creatinine, and triglyceride were measured in the cell culture after the treatment with metformin. Oil Red O staining method was used to stain the lipids in the cells.

Results

Metformin reduced significantly (p<0.001) VSMC proliferation in a concentration-dependent manner. With the increase of glucose uptake by VSMCs, the cell lipid deposition was not changed. Other biochemical parameters such as lactate, triglyceride, total protein, and creatinine were significantly changed in the cell culture (p<0.05).

Conclusions

Metformin increased the glucose uptake impacting metabolic pathways in VSMCs. It also increased the lactate efflux and protein metabolism without the change in cellular lipid deposition in high glucose conditions.
Die Forderung nach Kulteinheit. Beobachtungen zu Struktur und Genese von Dtn 12
Authors: Lee Sang-Won
Published: April 2022

Die gegenwärtige Forschung sieht den ältesten Baustein des Kulteinheitsgesetzes zumeist in Dtn 12,13–19. Der Beitrag zeigt, dass dies (wie auch ein Textanfang mit 12,8–12) aus sprachlichen und sachlichen Gründen nicht plausibel ist. Analytisch erweisen sich zudem die vermeintlichen Dubletten in 12,1–19 als pragmatisch erforderliche Entfaltungen des Gesetzes auf der Ebene des DtrG. Darüber hinaus erschließt sich der großflächige Numeruswechsel in Dtn 12 als strukturell stimmig. Demgegenüber hat der Abschnitt 12,20–28 (neben diversen punktuellen Interpolationen) als jüngere Ergänzung zu gelten. Das DtrG als primärer Kontext des Grundtextes schließt eine ältere deuteronomische Vorlage nicht per se aus, da der literargeschichtliche Befund für einen solchen Rückschluss nachweislich nicht hinreicht.
Sapientialised Priest?: Reconsidering the Priestly Torah in Sirach
Authors: Kwon JiSeong James
Published: April 2022

Scholars have maintained that Ben Sira belongs to a priestly group, or a circle of scribe-sages subjugated to priests, and that the book of Sirach hints at a merger of the created and priestly orders. The book’s harmonization of sapiential and Zadokite strands of Judaism might justify its identification with Jerusalemite priestly groups, but it is misleading to conclude that Sirach merges these two separate traditions. Its wisdom discourses are an adaptation of Proverbs in which Ben Sira, as a Jewish scribe, grants authority and power to the Zadokites on the model of Proverbs’ divine wisdom.
Partial substitution of the Mn atoms in CaMnO3by first row transition metal atoms: effect on oxygen vacancy formation
Authors: Grimm Benjamin , Bredow Thomas
Published: April 2022

Sustainable hydrogen production is one of the most challenging topics in modern energy economics. Electrochemical and thermal splitting of water are promising techniques, but are highly energy demanding. Efficient hydrogen evolution reaction catalysts can play a key role to lower the electrolysis potential and to make water splitting more feasible. Among other perovskites, CaMnO3has been identified as efficient electrode material due to its relatively high oxygen vacancy concentrations at elevated temperatures. But this compound needs to be further improved for technical use. In this study, the effect of Mn substitution in CaMnO3by 3d metals M = Sc, Ti, V, Cr, Fe, Co, Ni, Cu and Zn on the oxygen vacancy formation energy is investigated theoretically at DFT level. Vacancy formation energies, enthalpies and free enthalpies are calculated with a combination of hybrid and GGA density functionals. Configuration entropy is taken into account by calculating all possible configurations of M and oxygen vacancy site in supercell models. The calculated oxygen vacancy formation energies are strongly affected by Mn/M substitution, the most promising heteroelement being Cu. CaMn0.875Cu0.125O2.875and CaMn0.875Cu0.125O2.75are in equilibrium at 537 K, compared to 1231 K for CaMnO2.875/CaMnO2.75and 1350 K for CaMnO3/CaMnO2.875.
Synthesis, antimicrobial activity and modeling studies of thiazoles bearing pyridyl and triazolyl scaffolds
Authors: Funda Tay Naime , Berk Barkın , Duran Murat , Kayagil İsmail , Yurttaş Leyla , Biltekin Kaleli Sevde Nur , Yamaç Mustafa , Karaduman Ayşe Betül , Demirayak Şeref
Published: April 2022

In this study, novel 4-(5-((2/3/4-substituted benzyl)thio)-4-(4-substituted phenyl)-4H-1,2,4-triazol-3-yl)-2-(pyridin-3/4-yl)thiazoles were synthesized following a multi-step synthetic procedure. All the compounds were screened with a panel of gram positive/negative bacteria, yeasts, and molds for antimicrobial activity using the disc diffusion method. Then, the minimum inhibitor concentration (MIC) and the minimum bactericidal concentration (MBC) values of active compounds were determined against Micrococcus luteus, Bacillus cereus, Listeria monocytogenes, and Staphylococcus aureus using the broth microdilution technique. These compounds were also screened for their inhibitory activities against S. aureus DNA gyrase by supercoiling assay. Furthermore, the crystal structure of S. aureus DNA gyrase B ATPase was subjected to a docking experiment to identify the possible interactions between the most active ligand and the active site. Lastly, the in silico technique was performed to analyze and predict the drug-likeness, molecular and ADME properties of the synthesized molecules.
Clinical and Renal Cortical Blood Perfusion Characteristics in Patients with Severe Atherosclerotic Renal Artery Stenosis Who Underwent Stent Implantation: A Single-center Retrospective Cohort Study
Authors: Li Yan , Sun Youjing , Wang Siyu , Ma Na , Li Mengpu , Ren Junhong , Li Yongjun , Ai Hu , Zhu Hui , Wang Yang , Guo Fajin
Published: April 2022

Objective This study aimed to observe the clinical imaging features of patients with severe atherosclerotic renal artery stenosis (ARAS) receiving stent implantation, and to evaluate the associations between baseline clinical and imaging factors and renal-function deterioration at a 1-year follow-up.

Methods This study was a single-center retrospective cohort study. A total of 159 patients with unilateral severe ARAS who underwent stent implantation at Beijing Hospital between July 2017 and December 2020 were consecutively enrolled. According to the renal glomerular filtration rate (GFR), detected by radionuclide renal imaging at 1-year follow-up, all patients were divided into a poor-prognosis group (with a ≥30% decrease in renal GFR; n=32 cases) and a control group (127 cases). Clinical imaging data, including the renal cortical blood perfusion pre- and post-sent implantation, were analyzed. Univariate and multivariate logistic regression analysis was used to evaluate the associations between clinical and imaging factors and renal-function deterioration.

Results Of the 159 patients enrolled, 83 (52.2%) were men, with an average age of (57.2±14.7) years. The patient age, rate of diabetes, and systolic blood and diastolic blood pressure in the poor-prognosis group were significantly higher than those in the control group (all P<0.05). Before stent treatment, patients in the poor-prognosis group, compared with the control group, had a significantly smaller area under the ascending curve (AUC1), area under the descending curve (AUC2), and peak intensity (PI), and a longer time to peak intensity (TTP) and mean transit time (MTT) (all P<0.05). After stent treatment, patients in the poor-prognosis group, compared with the control group, showed significantly smaller AUC1, AUC2, and PI, and longer MTT (all P<0.05). Multivariate logistic regression analysis indicated that age (OR=1.251, 95%CI: 1.113–1.406, P=0.0002), diabetes (OR=1.472, 95%CI: 1.110–1.952, P=0.007), systolic blood pressure (OR=1.339, 95%CI: 1.082–1.657, P=0.007), renal GFR (OR=2.025, 95%CI: 1.217–3.369, P=0.006), and AUC1 post-stent (OR=2.173, 95%CI: 1.148–4.113, P=0.017) were the factors associated with renal deterioration at the 1-year follow-up.

Conclusions Patients with severe RAS with renal-function deterioration after stent implantation were older, and often had diabetes, hypertension, and impaired renal cortical perfusion. Age, diabetes, systolic blood pressure, renal GFR, and AUC1 after stent implantation were independent factors associated with short-term renal deterioration.
U.S. Border Militarization and Foreign Policy: A Symbiotic Relationship
Authors: Coyne Christopher J , Goodman Nathan P
Published: April 2022

U.S. government security along the U.S.–Mexican border has been increasingly militarized. This domestic militarization has been influenced by U.S. government military intervention abroad. Preparing for and executing foreign interventions involves investing in physical and human capital to effectively coerce and control the target population. The U.S. government’s “war on drugs” and “war on terror” created the conditions for this capital to be repurposed for domestic use in border-security efforts. While foreign policy created the conditions for border militarization, border militarization has also influenced foreign interventions. This article explores the symbiotic relationship between U.S. border militarization and foreign policy.
Paradiplomacia: una estrategia para la construcción de justicia socioespacial en el barrio Moravia de Medellín
Authors: Ávila Duque Victoria
Published: April 2022

La globalización ha producido cambios en la interacción de todos los niveles del sistema internacional y ha dado paso al surgimiento de nuevos actores como las ciudades. Así, las entidades subnacionales han establecido contactos directos transfronterizos de manera cada vez más frecuente. Esta práctica ha sido conocida desde la década de 1980 como paradiplomacia y, aunque el concepto ha sido poco desarrollado, el fenómeno al que se refiere no es nuevo, pues data de la década de 1950. El presente articulo busca primero, analizar la incidencia de la paradiplomacia, en general, y de la cooperación descentralizada, en particular, en el proceso de construcción de justicia socioespacial en la transformación del “Morro” de Moravia en la ciudad de Medellín y, segundo, realizar un aporte al avance de los estudios sobre paradiplomacia en el ámbito académico. Se concluyo que el proyecto de mejoramiento del “Morro” de Moravia es un ejemplo de como la paradiplomacia, a través de la cooperación descentralizada, puede aportar al mejoramiento de la ciudad y a la construcción de justicia socioespacial. La metodología utilizada es la documentación, principalmente, la exegesis de textos de fuentes primarias y secundarias y la revisión de material de divulgación audiovisual.
Para além da integração e do isolamento: mobilidades e presenças na Amazônia urbana
Authors: Candotti Fabio Magalhães , Melo Flávia
Published: April 2022

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Erratum - Journal Scientia Medica v.31 n.1 (2021) - ID 40589
Authors: Periódicos EDIPUCRS
Published: April 2022

The Editorial Team of Journal SCIENTIA MEDICA publishes the following changes and replacements, in the edition 31, n. 1 (2021), DOI: https://doi.org/10.15448/1980-6108.2021.1.40589, ID 40589, article, The 12 women who won the Nobel Prize in Medicine or Physiology
A new species and a new record of Malaxis (Malaxidinae) from Costa Rica
Authors: Chinchilla Isler F. , Karremans Adam P. , Blanco Mario A.
Published: April 2022

We describe and illustrate a new species and a new record of Malaxis from the lower montane and montane forests of Costa Rica. Taxonomic descriptions, illustrations, distribution maps, and conservation assessments are provided for each species. Malaxis excentrica sp. nov. is morphologically similar to Malaxis simillima, from which it can be distinguished by having a single leaf per sympodial unit, shorter, obovate, erect petals parallel to the column, the lip with triquetrous, acute, convex apical margin and the disc cavity divided by a costa. Malaxis pittieri is formally recorded for the flora of Costa Rica; Costa Rican specimens of this species were previously confused with Malaxis majanthemifolia. A lectotype for Microstylis pittieri is formally designated.
High performance thin layer chromatography (HPTLC) method development and validation for the simultaneous determination of paracetamol, caffeine, chlorpheniramine and phenylepherine in tablet formulation
Authors: Arage Almaz , Layloff Thomas , Hymete Ariaya , Ashenef Ayenew
Published: April 2022

A rapid, selective, and precise high performance thin layer chromatographic method was developed and validated for the simultaneous analysis of paracetamol, caffeine, phenylephrine and chlorpheniramine in tablets. The chromatographic analysis was carried out on glass plates pre-coated with silica gel 60 F254 as a stationary phase. The optimized mobile phase was methanol : n-butanol : toluene : acetic acid (8:6:4:0.2 v/v). TLC chamber of 10 × 20 cm was used with saturation time of 15 min. The retardation factor (RF) for chlorpheniramine, phenylephrine, caffeine and paracetamol was found to be 0.15 ± 0.02, 0.29 ± 0.02, 0.50 ± 0.02, 0.68 ± 0.02 respectively. Detection was carried out at 212 nm. Validation study was done following ICH Q2 (R1) guideline. The regression data for the calibration plots showed good linear relationship with R2 = 0.997 over the concentration range of 300–1,500 ng band−1 for caffeine, R2 = 0.996 over the concentration range of 100–500 ng band−1 for phenylephrine, R2 = 0.996 over the concentration range of 200–600 ng band−1 for chlorpheniramine, R2 = 0.998 over the concentration range of 400–2,400 ng band−1 for paracetamol. The method was validated for precision, accuracy and recovery. Minimum detectable amounts were found to be 304.9 ng band−1, 87.88 ng band−1, 117.18 ng band−1 and 143.06 ng band−1 for caffeine, phenylephrine, chlorpheniramine, and paracetamol respectively while the limit of quantification was found to be 923.95 ng band−1, 266.32 ng band−1, 355.11 ng band−1, and 433.53 ng band−1 in the same order. The method was successfully applied to analyze two marketed tablets in a selective and reproducible manner.
Absinthe against multi-drug resistant bacterial pathogens? A recent update on the antibacterial effects of Artemisia compounds
Authors: Janz Josephine , Shayya Nizar W. , Bereswill Stefan , Heimesaat Markus M.
Published: April 2022

The widespread misuse of antibiotics leads to a rapid development of multi-drug resistant (MDR) bacterial pathogens all over the globe, resulting in serious difficulties when treating infectious diseases. Possible solutions are not limited to the development of novel synthetic antibiotics but extend to application of plant-derived products either alone or in combination with common antibiotics. The aim of this actual review was to survey the literature from the past 10 years regarding the antibacterial effects of distinct Artemisia species including Artemisia absinthiae constituting an integral component of the Absinthe drink. We further explored the synergistic antibacterial effects of the Artemisia plant products with established antibiotics. The survey portrays the Artemisia derived compounds as potent antibacterial agents that can even restore the efficacy of antibiotics against MDR bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) and MDR Escherichia coli. This, in turn, is presumably triggered in part by the interaction of the Artemisia ingredients with the efflux pumps of MDR bacteria. In conclusion, biologically active molecules in Artemisia plants enhance the antibiotic susceptibility of resistant bacteria, which provide promising future therapeutic strategies to combat MDR bacterial pathogens.
ANALISIS KESESUAIAN KAWASAN WISATA PANTAI TELUK BETUNG TIMUR, BANDAR LAMPUNG
Authors: Fauzi Muhammad Aldhiansyah Rifqi , - Rismansyah , Bulgandi Ario Dwi , Hidayatullah Rismun
Published: April 2022

Pantai Duta Wisata, Puri Gading dan Tirtayasa merupakan pantai wisata yang terletak di wilayah administrasi Pemerintah Kota Bandar Lampung, Provinsi Lampung. Ketiga pantai ini mempunyai karakteristik yang hampir mirip yaitu mempunyai arus yang tenang karena terletak di Teluk Ratai Lampung. Penelitian ini dilakukan pada April 2020 untuk menentukan kesesuaian pantai sebagai wisata rekreasi dengan menggunakan Indeks Kesesuaian Wisata. Hasil dari penelitian ini menyatakan bahwa pantai Duta Wisata mendapat Indeks Kesesuaian Wisata (IKW)74 %, Pantai Tirtayasa mendapatkan nilai IKW 80% dan pantai Puri Gading mendapatkan nilai IKW 68%. Ketiga pantai ini mendapatkan predikat sesuai untuk kategori wisata berenang
UPAYA PEMECAHAN PERMASALAHAN USAHA PERIKANAN BUDIDAYA DI KECAMATAN PONJONG KABUPATEN GUNUNGKIDUL PROVINSI DAERAH ISTIMEWA YOGYAKARTA
Authors: Syarifudin Riva Bayu
Published: April 2022

Kecamatan Ponjong merupakan wilayah di Kabupaten Gunungkidul yang memiliki potensi sumberdaya perikanan yang masih dapat dikembangkan. Penelitian ini bertujuan untuk mengidentifikasi potensi, menganalisis permasalahan budidaya ikan dan strategi pemecahan masalah usaha perikanan. Metode penelitian menggunakan metode survey melalui observasi dan wawancara kepada responden yang berjumlah 28 pembudidaya ikan nila dan lele. Hasil penelitian menunjukkan sumber air untuk usaha perikanan mengandalkan mata air yang berasal pada sumber beton. Mayoritas penduduk di Kecamatan Ponjong mengeyam pendidikan di tingkat SD. Usaha budidaya ikan di Kecamatan Ponjong masih tradisional. Analisis permasalahan mengunakan metode SWOT, maka diperoleh strategi pemecahan masalah dengan, pendampingan penyuluhan mengenai pakan mandiri yang lebih murah, menerapkan biosecurity, meningkatkan mutu dan kualitas produk perikanan.
ANALISIS DAYA DUKUNG KAWASAN DAN POTENSI EKOWISATA BAHARI DI PROVINSI BANTEN
Authors: Rahman Abdul
Published: April 2022

Potensi wisata di Provinsi Banten yang menarik minat wisatawan diantaranya adalah pada wisata bahari (Pantai Anyer, Tanjung Lesung, Pantai Sawarna, Pulau Peucang, dan Pulau Burung). Penelitian ini bertujuan untuk mengetahui Daya Dukung Kawasan (DDK), Indeks Kesesuaian Wisata (IKW) ekowisata bahari dan untuk menganalisis potensi nya di Provinsi Banten. Penelitian ini dilakukan di 4 Kabupaten dan 1 kota, dengan 11 lokasi objek wisata yang dijadikan sampel. DDK di 11 lokasi pantai tertinggi yaitu 180 orang/50 mpanjang pantai yaitu di Pantai Sawarna (Lebak), di Pantai Pulau dua (Serang) dengan DDK 20 orang/50 mper hari. DDK wisata mangrove didapat dari dua lokasi yaitu PRPM Kronjo (Tangerang) dengan 72 orang/50 m2  dan Cagar Alam Pulau Dua (Serang) dengan 32 orang/50 m2  per hari. Sedangkan untuk DDK wisata snorkeling yang tertinggi yaitu; Spot Ciapus 8 orang/50 m2, dan terendah di Pulau Badul 3 orang/50 m2 per hari. Pantai Pulau Peucang (Uj. Kulon) memiliki nilai IKW tertinggi yaitu 96.67% dan yang terendah di Pantai Pulau Cangkir (Tangerang) yaitu 55.6%, Kategori rekreasi mangrove terdapat di dua lokasi yaitu; ekowisata mangrove PRPM Kronjo dengan nilai IKW 55.55% dan ekowisata mangrove Cagar Alam Pulau Dua dengan nilai IKW tertinggi 81.25%. Kategori rekreasi snorkelling tertinggi yaitu; Spot Legon Sumino dengan Nilai IKW 91.23% dan terendah di Pulau Badul dengan Nilai IKW 80.7%.
PROSES PENGOLAHAN FILLET IKAN KERAPU (Epinephelus Sp) BEKU DI PT. BINTAN INTAN GEMILANG, BINTAN – KEPULAUAN RIAU
Authors: Sirait Jaulim , Siregar Arpan Nasri , Mayangsari Tri Putri , Sipahutar Yuliati H
Published: April 2022

Grouper fish is an important commodity in Indonesian waters which has bright marketing prospects, both domestic and export. Grouper fish is Indonesia's leading non-oil and gas export commodity, in addition to seaweed, shrimp and tuna. Indonesia is the world's largest export of grouper, especially live grouper exports. This study aims to see the processing of frozen grouper fillets. The method is carried out by observation and survey, by directly following the entire processing process, from receiving raw materials to transportation, by conducting quality testing (organoleptic and microbiological), cold chain observation, yield, labor productivity. Data analysis was done descriptively. The results showed that the processing was carried out properly according to SNI No. 2696: 2013 concerning frozen fish fillets. The results of the organoleptic quality test of raw materials and final products were 8, microbiological tests ranged from 3 × 103 cabbage / gr for the ALT test, <3.0 APM / gr for the E. coli test and negative results for the Salmonella test, according to SNI. The application of cold chain has done well with the raw material temperature of grouper 1.580C. The yields in the filling and tidying process averaged 49.9% and 64.6%, according to company standards. The labor productivity in the filling and tidying process was 97.79 and 107.89 kg / hour / person, according to company standards.
Study on the role of nutrients in food to improve the motion state of athletes
Authors: Zhou Hongkai
Published: April 2022

This study aims to analyze the role of nutrients in food in improving athletic performance and to understand the feasibility of food supplementation in sports training. Twenty athletes were randomly divided into two groups, A and B. The athletes in the two groups had the same diet and the same training content and differed only in the supplemented food. Group A was supplemented with Siraitia grosvenorii water, and Group B was supplemented with pure water. After 3 months of training, the body composition, exercise status, and blood indexes of the athletes in the two groups were compared. Compared with the athletes in group A before the experiment as well as in group B after the experiment, the athletes in group A showed a significant increase in fat-free weight, improved athletic performance, increased levels of hemoglobin (Hb) and red blood cell (RBC), and decreased levels of blood lactic acid (BLA) and blood urea nitrogen (BUN) (P < 0.05). Nutrients in food can effectively improve the body composition and exercise status of athletes and inhibit the decrease of Hb and RBC as well as the increase of BLA and BUN, which have good usability in sports training.
Arnaldus de Villa Nova and his ideological “cliché” as a physician, theologian and alchemist. On the question of the image in Russian-language biographies and the history of medicine
Authors: Rodionova Yu. V.
Published: April 2022

In Russian historiography, the biography of Arnaldus de Villa Nova begins with the words “doctor and alchemist”, and then all the arguments go into myth-making, although Arnald’s writings are very well studied at the modern scientific level, but are inaccessible to reading due to the language barrier. An accurate understanding of the biography of Arnaldus de Villa Nova is important for researchers of the history of medicine, Medieval historians and historians of Church history, since the activity of this man influenced significant events of the late XIII — early XIV centuries, and he is known to the Russian-speaking environment only by the verses attributed to him.
Treatise De adventu Medici ad aegrotum — the attitude of doctors to the disease and its treatment, an example of the Salerno Medical School
Authors: Rodionova Yu. V.
Published: April 2022

The article presents a translation of an anonymous treatise De adventu Medici ad aegrotum in Russian, the origin of which is attributed to the Salerno School of Medicine. Using the example of the treatise, it is possible to determine what characteristic the doctors of the XIII century attached to the disease, and the tasks of the doctor’s craft.

The philosophy of healing the body is based on an understanding of nature as an instrument created by God, and not on the influence of divine power (will), which makes a decision about healing in each individual case (individually for each patient). The origin of the disease of the body is considered a consequence of some kind of influence on substance, an overabundance of substance affects nature, which resists and strives for the return of balance and its integrity.
Cure, healing, magic, superstition: the symbolism of the mandrake in Antiquity and the Middle Ages from the point of view of Hugo Rahner
Authors: Buzykina I. N.
Published: April 2022

The article reviews the idea of cure or healing in Late antiquity, which was accepted by Christian tradition. According to this tradition, the healing effect is emerging simultaneously both in body and soul, and the very idea of cure or healing falls into spiritual dimension. In mediaeval Christianity this concept of healing takes its form as folklore-medicine way of theurgy, or it appears as a pure allegory or symbolic interpretation in a miracle-play, or, in alchemy. This essay is trying to discuss the early Christian concept of healing or cure from the later Christian humanistic point of view, which was presented in Hugo Rahner’s book Greek Myths and Christian Mystery, first published in 1945.
INTEGRAÇÕES DESINTEGRADAS: OS (DES)CAMINHOS DA EDUCAÇÃO PROFISSIONAL E “TECNOLÓGICA” NO BRASIL
Authors: Silva Marcelo
Published: April 2022

Quando se fala em política de educação profissional e tecnológica, encontra-se presente como mediação fundamental os tipos de capitalismo e classes sociais, bem como a posição do Estado nas relações internacionais. No Brasil, contraditoriamente, constituiu-se um senso comum e difunde teorias educacionais descoladas das questões estruturais do Estado, do capitalismo e das classes sociais. O artigo em questão busca contestar a formação e desenvolvimento da chamada Rede Federal , seu claro centenário e sua relação fundamental com as classes sociais, o capitalismo e o Estado brasileiro. Trata-se de questão central, em um contexto de desindustrialização e redimensionamento de colônia de exportação de commodity .
El carácter sancionatorio del régimen de inhabilidades e incompatibilidades
Authors: Barreto-Moreno Antonio Alejandro , Pulido-Ortiz Fabio Enrique
Published: April 2022

En el derecho administrativo contemporáneo se resalta la función sancionatoria de su autoridad. Este artículo explica la forma en que esta característica ha impactado en la implementación del régimen de inhabilidades e incompatibilidades de la contratación pública en el derecho colombiano. Para ello, se identifican dos formas de implementar este régimen: 1) la regulación de las inhabilidades e incompatibilidades como normas para la limitación a la capacidad de realizar determinados actos jurídicos y 2) la incorporación de las inhabilidades e incompatibilidades como parte del contenido de reglas jurídicas sancionatorias. En el escrito, y a partir de la conceptualización de las reglas sancionatorias, se concluye que el régimen actual de inhabilidades e incompatibilidades de la contratación pública en Colombia es de carácter sancionatorio
La formazione umanistica per il Brasile del futuro : le sfide di efficacia dei diritti e doveri educativi in prospettiva umana.
Authors: Cangelosi Annalisa , Padilha dos Santos Rafael
Published: April 2022

Obiettivo: Questo articolo intende stimolare una riflessione sullo stato dell’offerta formativa brasiliana, in particolare per ciò che riguarda le discipline umanistiche. Metodologia: Viene posto particolare accento sulla deprivazione che le istituzioni educative brasiliane hanno pagato – e tuttora pagano – in conseguenza della colonizzazione culturale avviata negli anni della dittatura militare. Risultati: Il problema viene inquadrato in un’ottica più ampia, considerando il rapporto tra educazione e globalizzazione economica nella società di mercato – da un punto di vista tanto globale quanto particolare, secondo l’ottica del Brasile – e di quanto questa relazione incida nei risultati ottenuti in campo formativo. Conclusioni: Infine, vengono richiamati alcuni passaggi che la visione ontopsicologica espone sul ruolo del Brasile nel panorama globale del nuovo umanesimo, e offre alcune proposte di soluzione alle criticità tuttora presenti.
Facebook : derechos afectados y aspectos jurídicos de la red social.
Authors: Ortega Ruiz Luis Germán
Published: April 2022

Las redes sociales se han constituido en una de las creaciones con mayor incidencia en el diario vivir de las personas, convirtiéndose en un medio de interacción social. Una de las redes sociales más conocida y con mayor número de usuarios es Facebook, la cual es objeto de investigación en el presente trabajo con el fin de establecer y determinar su incidencia en el desarrollo jurídico de derechos, deberes y libertades. Específicamente se pretende describir los derechos que se ven amparados y vulnerados con su uso y manejo como elementos para la generación de políticas públicas, teniendo presente, igualmente, sus propias políticas. Para lo anterior se interroga:¿Cuál ha sido la regulación jurídica que se ha desarrollado frente al uso de la red social Facebook? La respuesta a dicho interrogante tiene como hipótesis que la red social Facebook materializa derechos y libertades a través del acceso a la Internet como derecho fundamental. Por lo anterior, se busca determinar la viabilidad de plantear una política pública de autorregulación para el uso de redes sociales bajo el esquema de principios jurídicos descartando el sistema de regulación reglada.
El enfoque cultural del desarrollo y los derechos culturales como propuesta para la redimensión de la reparación colectiva
Authors: Marún Uparela Katleen
Published: April 2022

Otorgar una importancia superficial a lo cultural en el marco de la reparación colectiva, particularmente a las afectaciones causadas en este ámbito a grupos y comunidades de víctimas, puede generar serias repercusiones sobre la integralidad de la reparación y su efecto transformador. En ese sentido, se hace necesaria una reflexión en torno a la reparación colectiva que tome como postulado esencial la inclusión de lo cultural en el proceso, lo que constituye el objetivo principal de este trabajo. Para ello, se retoman metodológicamente los apuntes teóricos del enfoque cultural del desarrollo y otros enfoques que lo alimentan, como elemento clave hacia una redimensión formal y operativa de la reparación colectiva. Finalmente, esta redimensión permite potenciar su pretensión trasformadora y abrir la puerta a procesos de desarrollo local y comunitario, para hacer posible tanto la agencia de sus derechos como víctimas, así como de sus derechos en tanto personas y ciudadanía.
Diseño y análisis psicométrico de un instrumento para evaluar victimización judicial en víctimas durante la etapa de denuncia
Authors: Mantilla Ojeda Saida L. , Avendaño Prieto Bertha Lucía
Published: April 2022

Los operadores judiciales en algunas ocasiones pueden revictimizar a quienes denuncian un hecho delictivo. El objetivo de la presente investigación es diseñar un instrumento para evaluar este tipo de victimización, el cual se realizó con base en los planteamientos sobre victimización secundaria y la evidencia empírica arrojada por las entrevistas realizadas a 18 víctimas que interpusieron denuncias. El estudio piloto se efectuó con 367 personas, la prueba final se aplicó a 825, con 336 se realizó un análisis factorial exploratorio y con las 489 restantes, un análisis confirmatorio. Los participantes fueron personas mayores de 18 años, de diferente estado civil, orientación sexual, nivel educativo, estrato, ocupación y ubicación geográfica. La validación de contenido del instrumento se realizó con once expertos. La consistencia interna del instrumento, los análisis factoriales y el ajuste de los ítems al modelo de Rasch, indicaron que el instrumento es válido y fiable.
La legitimidad de los actos administrativos electrónicos en el marco de las actuaciones administrativas
Authors: Mondragón Duarte Sergio Luis
Published: April 2022

La presente investigación tiene como objetivo dar a conocer la legitimidad de los actos administrativos electrónicos en el marco de las actuaciones administrativas, para lo cual se aborda el tema por medio de un enfoque cualitativo, basado en el método hermenéutico, que permite dilucidar el alcance de los resultados de la investigación por medio de la interpretación de textos normativos, jurisprudenciales y doctrinales.

En ese sentido, partiendo de una revisión documental exhaustiva de fuentes bibliográficas confiables, se obtiene como resultado principal de esta pesquisa, que los actos administrativos electrónicos tienen la misma validez que los actos administrativos físicos, siempre que satisfagan los requisitos de autenticidad, integridad y disponibilidad, para efectos probatorios, tanto ante la misma administración como ante la administración de justicia, en el marco del principio de equivalencia funcional.
Experiencias: trazos de resistencias
Authors: Ramírez Monsalve Paula Andrea , Roldán Salas Hernando
Published: April 2022

El presente escrito, explora diversas posibilidades conceptuales de la resistencia. Intenta describir algunas nociones relacionadas con los ejercicios decontrol y sometimiento, sujetos (agentes) resistentes, prácticas transformadoras, lucha por el reconocimiento, rupturas, subjetivaciones de experiencias, tejidos del quehacer; y desde allí se arroja a la tarea de contrastar, incluso, dar a conocer cómo ciertos teóricos asumen la resistencia en términos universales y topológicos, otros, simplemente le restan importancia. A través de metodologías histórico-descriptivas, los autores indagan por perspectivas críticas de significación, subjetivación e incorporación de práctica, por cierto, creativas, al momento de resistir. Acuden a la noción de potencia, relacionan la resistencia con la cultura y los horizontes de transformación, para aproximar significados otros, que manifiestan comportamientos no interesados en el poder, pero sí en la autonomía y en la afirmación de sus prácticas de existencia.
El derecho transnacional y la consolidación de un pluralismo jurídico transnacional
Authors: Piffer Carla , Márcio Cruz Paulo
Published: April 2022

Este artículo, cuyo objetivo es tratar el tema del derecho transnacional y la posibilidad de consolidación de un pluralismo jurídico transnacional, se inicia con consideraciones acerca de la transnacionalidad como un fenómeno que caracteriza la actual sociedad mundial. A continuación, se vislumbra la posibilidad de la construcción de un pluralismo jurídico transnacional a partir del derecho transnacional, totalmente diferente del pluralismo jurídico clásico. Finalmente, se concluye que es imprescindible alejar cualquier intento de mantener un pluralismo sujeto a actos jurídicos de comparación y convergencia, ante la necesidad de utilizarse también la coordinación e integración entre sistemas jurídicos y no jurídicos, elevando el desafío de los fenómenos que trascienden fronteras y superando modelos categorizados a nivel local, internacional, supranacional o global. La metodología por usar comprende el método inductivo, utilizándose las técnicas del referente, de la categoría, de los conceptos operacionales y de la investigación bibliográfica.
Towards class arbitration in the consumer law in Colombia. A reference to the AT&T mobility llC v. Concepcion case
Authors: Salgado Figueroa Eduardo
Published: April 2022

This article highlights a new discussion in Colombia, that is, the role that arbitration could play in consumer law. The paper also analyses a signature case in U.S. arbitration consumer law (AT&T Mobility v Concepcion), which offers the basis to open the debate of small claims contested during a ClassArbitral proceeding. It also weighs on the legal nature of Class Waiver Clause. It furthers on the possible sanctions that could be imposed on that clause, to conclude that Consumer Law in Colombia deserves a better and effective procedure favoring consumers by voiding with inefficacy a possible Class Waiver in an arbitration agreement.
Diagnostic significance of combined immunohistochemical panel of p63, High Molecular Weight Cytokeratin (34betaE12) and α‑Methyl Acyl Co A Racemase (AMACR) in resolving suspicious foci in prostatic lesions
Authors: Nida Malik , Veena Maheshwari , Mohsin Aijaz , Nishat Afroz
Published: April 2022

Background: The assessment of small foci of atypical glands in prostatic needle biopsy specimens is a key diagnostic challenge in routine histopathology for pathologists. Due to the presence of mimickers of prostate carcinoma, at times making a definitive diagnosis becomes difficult. The use of immunomarkers like α‑Methyl Acyl Co A Racemase (AMACR), p63 and High Molecular Weight Cytokeratin (HMWCK/34betaE12) has made it easier for us to reach the diagnosis in such cases. Material and methods: All the cases which were received in the Department of Pathology, JNMCH, AMU from January 2015 to December 2018 were categorized into four histomorphologic groups on the basis of histopathology, and immunohistochemistry was applied on all the cases which were rendered ‘suspicious’ on histomorphology. Result: One hundred twenty-one prostatic specimens were received. Out of which, 13 biopsies were found to be inadequate for analysis and hence were not included in the study. Out of the rest 108 cases, (1) 52 were benign, (2) 19 were premalignant, (3) 25 were carcinoma and (4) 12 were signed as ‘suspicious’ on histopathology. These 12 suspicious cases were true cut needle biopsies which were considered appropriate for applying immunomarkers along with control cases. Out of 12 suspicious cases, 8 cases (66.7%) were negative and 3 cases (25%) were weakly positive for p63, 1 case showed moderate immunostaining. HMWCK was completely negative in 7 cases (58.33%), 3 cases (25%) showed weak positivity, 1 case showed moderate and 1 case showed strong positivity. While 5 cases (41.67%) were negative and 7 cases (58.33%) were positive for AMACR mostly showing moderate to strong positivity Conclusion: The application of immunomarkers helped us to reach a definite diagnosis in 10 out of 12 cases, which were otherwise difficult to classify. Judicious use of immunomarkers can help in differentiating mimickers of prostate carcinoma from true cancer cases and assist in reaching a definitive diagnosis.
[RETRACTED] NextGen Pharma Keto Max - What Are The Pros and Cons of NextGen Keto Fat Burners? - News v1
Authors: Pharma Keto NextGen
Published: April 2022

[RETRACTED]

NextGen Pharma Keto
Stranded Transcript Count Table Generation from Long Reads v2
Authors: A Eccles David
Published: April 2022

This protocol is for comparing different samples at the transcript level, using long reads that are mapped to transcripts. Input(s): demultiplexed and oriented fastq files (see protocol Preparing Reads for Stranded Mapping), transcript reference fasta file, annotation file Output(s): transcript table, sorted by differential coverage, annotated with gene name / description / location