bluuebunny/crossref_metadata_2025 huggingface dataset:
Stem-cells Research and Therapies
Authors: Aziz-Andersen Kaiser J.
Published: February 2024

Studies with leucogenenol, a compound isolated from the metabolic products of Penicillium gilmanii and human liver showed that leucogenenol accelerated the rate at which the “functional” cells, neutrophils, red blood cells and lymphocytes developed in the bone marrow from their corresponding committed precursor cells. It was found that the neutrophils that appear in the peripheral blood circulation following injection of leucogenenol originated from the neutrophils in the bone marrow. A scheme was presented to show that leucogenenol and adroxazine play key roles in regulating the circulation of blood cells. Stem cells act as the building blocks for the tissues and organs of physiologic systems. Research studies have shown stem-cells potential to treat a wide range of diseases. The Stem-cells play important roles in the treatment of various medical conditions and monitoring of bodily functions. Stem-cell therapy has shown results in treating conditions via peripheral blood circulation in the growth of new blood vessels such as heart disease, diabetes, cancer, Parkinson’s disease. Clinical trials are being conducted to assess the safety and efficacy of stem cell based-therapies in treating various diseases such as Chronic Myelogenous Leukemia (CML) which is a type of blood cancer that affects the bone marrow and blood cells characterized by the abnormal growth of white blood cells that affects the bone marrow and blood cells known as myeloid cells. Stem cell therapies have great potential to become one of the most important tools of regenerative medicine and untreatable diseases. In this review, different types of stem-cell-based therapies are described, which are used in treating various diseases.

Keywords: Blood Stem cells, therapies, clinical trials, CRISPR Therapeutics
Reqomp: Space-constrained Uncomputation for Quantum Circuits
Authors: Paradis Anouk , Bichsel Benjamin , Vechev Martin
Published: February 2024

Quantum circuits must run on quantum computers with tight limits on qubit and gate counts. To generate circuits respecting both limits, a promising opportunity is exploiting uncomputation to trade qubits for gates. We present Reqomp, a method to automatically synthesize correct and efficient uncomputation of ancillae while respecting hardware constraints. For a given circuit, Reqomp can offer a wide range of trade-offs between tightly constraining qubit count or gate count. Our evaluation demonstrates that Reqomp can significantly reduce the number of required ancilla qubits by up to 96%. On 80% of our benchmarks, the ancilla qubits required can be reduced by at least 25% while never incurring a gate count increase beyond 28%.
Essays on Business and Politics in Resource-abundant, Low-income Countries
Authors:   , Schilling Sören Felix
Published: February 2024

This dissertation examines links between politics and businesses in resource-abundant, low-income countries. I argue that privatizations and the awarding of property rights do not separate business and politics per se. Instead, they shift the way these two spheres interact. Whether this shift leads to socio-economic development, depends on the re-spective implementation of property rights. Each chapter of this dissertation examines therefore with quantitative methods on a micro level how powerful actors control, allocate and regulate assets in the private sector. Chapter One and Two explore the phenomenon of cronyism, where firms and politicians engage in trades to obtain mutual benefits in the case of Mozambique, a country that established market oriented reforms and experi-enced a resource fuelled FDI bonanza from 2009 onwards. The first chapter focuses on business partnerships or co-investment as a means for politicians to gain private benefits from holding political office. Chapter Two focuses on political selection and finds that the ruling elite in an electoral autocracy constructs and co-opts the emerging business elites into positions of raising economic sector. Chapter Three examines whether the awarding of mining licenses in the DRC and its neighboring countries reduces the link between the economic value of a mine and local levels of conflict. This chapter identifies property rights gaps as an important constraint to such formalization efforts and underscores the necessity for independent stakeholders to monitor the design and enforcement of property rights.
Forraje verde hidropónico como alternativa alimenticia en pollos de engorde (gallus gallus domesticus)
Authors: Castañeda Villarreal Diana Marisol , Orjuela Hueso Andrés Felipe , Marmolejo Villa Angie Paola
Published: February 2024

Broilers are part of the Colombian diet in a significant way, for which most of their production is done using concentrates, representing a high cost in their production and a dependence on these. Finally, the use of hydroponic green corn fodder, and an organic diet based on cassava, produced in the area of ​​the experiment, is proposed to identify if it is efficient in terms of weight gain, against a commercial feed. Carrying out the breeding of 16 chickens to which 8 are supplied with the diet of hydroponic green fodder with cassava (Manihot esculenta Crantz), and the other 8 a commercial diet, analyzing the weekly weight gain of each group and in the same conditions. weather and location. Resulting in a small study group for the analysis of the food supplied.
Aplicación de big data en sistemas de salud pública
Authors: Lopez Copete Andres Felipe , Rodriguez Martinez Libardo , Ramírez Gómez Daniel Alexander
Published: February 2024

This article mentions a series of strategies and success stories that, through their correct application, allow improving patient care in public health information systems, in turn, with the optimization of resources, efficiency levels are increased in all care processes such as inventory management, personnel management, prevention and timely diagnosis of infections. All this is achieved using Big Data tools, which allow forecasting and preventing infections or diseases through analytical components, with millions of data that are captured from diverse sources, stored in repositories, and processed with different algorithms that facilitate their interpretation, for efficient decision-making and resource management, not only at the health level, but also at the government level. On the other hand, a series of investigative challenges are generated which are mostly associated with privacy policies, security, and information laws where the role of government entities is essential to be able to achieve a mature relationship between technology and health.
La informática como herramienta elementan en el desarrollo económico de despachos contables en Jonuta, Tabasco
Authors: López Gómez Miguel , García Álvarez Aída Dinorah , Román Guillén Domingo
Published: February 2024

At present, information technology is the basic tool in accounting firms since it allows generating labor skills, reducing errors or loss of accounting information from clients, for which accountants apply the use of programs such as Excel, Aspel COI, Aspel NOI and SAT. that are specified in accounting activities. In this article, the study plan was analyzed, the relationship with the graduate profile and the labor field was evaluated, emphasis was placed on evaluating the impact of current technological advances in accounting, and business tax processes. In addition, it is taken into account that accountants are attached to changes in the management of technological tools for administrative and treasury processes presented by the tax administration. The objective of the research is to establish what the technological competences of the public accountant are, so that in this way they can face the problems imposed by the challenges and opportunities of their profession, managing in a more effective way the accounting systems of exercises, going from a manual registration to those supported by computer systems. The results generated by the analysis of the study plan, an evaluation of the relationship with the graduate profile and the labor field of the Lic was carried out. In UJAT public accounting, emphasis was placed on the evaluation of the impact of the technological advances present in digital accounting.
Identificación de pérdidas de alimentos e insumos agropecuarios desde laplaneación Agrologística. Experiencia en el departamento del Huila
Authors: Correa Nuñez Andres Camilo
Published: February 2024

Se presentan los antecedentes normativos y la articulación de la política pública relacionada con la reducción de pérdida y desperdicios de alimentos, y el ordenamiento del sector agropecuario a través del Decreto Ley 4145 del 3 de 2011, su relevancia en el Plan Nacional de Desarrollo 2022-2026 ‘Colombia, potencia mundial de la vida’, a través de los Ejes Estratégicos: 1) Ordenamiento del territorio alrededor del agua y justicia ambiental, y 3) Derecho Humano a la Alimentación, y su relación con los ODS en Colombia, especialmente el ODS 12 -Producción y Consumo responsables- y de forma indirecta con el ODS 2 – Hambre Cero-.También se debe mencionar que la UPRA ha participado en todo el proceso de implementación y reglamentación de la Ley 1990 de 2019, en el marco de la ‘Mesa técnica de Pérdidas y Desperdicios de Alimentos’, instaurada por la CISAN y a partir de la cual se estructuró la ‘Política para la prevención y la disminución de las pérdidas y los desperdicios de alimentos en Colombia’ que fue aprobada por esta Comisión y adoptada a través del Decreto 375 de 2022. Aquí, la UPRA asumió responsabilidades específicamente con la formulación de los Planes de Agrologística, donde se desarrollan los formularios de los procesos de abastecimiento, almacenamiento, y transporte y distribución, en ellos se indaga sobre las proporciones de pérdidas y desperdicios generados en estos procesos, sus causas y posibles soluciones concertadas directamente con los actores que realizan estas actividades.
Evaluación de la reducción de pérdidas de tomate (solanum lycopersicum) a partir de la adaptación de un sistema de envase en el proceso logístico de transporte
Authors: Povea Garcerant Ismael
Published: February 2024

In order to evaluate the reduction of tomato (Solanum lycopersicum) losses from the adaptation of the traditional container for its transport, a diagnosis was made in which all the characteristics and variables to be taken into account in the harvest and post-harvest processes of the fruit were observed, in order to identify factors that could affect the losses of this foodstuff. Taking into account the previous phase, the possible materials for the adaptations to the traditional container were evaluated, which consisted of the lining of the internal walls of the container. These materials were fique sacking (CA1) and injected polyethylene (CA2). The baskets with adaptations were placed in the customary transport for transportation to the point of sale, taking a total of 20 kg for physiological and physicochemical characterization, for subsequent statistical analysis using R Studio software. The results indicate that weight loss is one of the characteristics most influenced according to the adjustments made. In addition, a significant difference was observed between the units in the container with injected polyethylene adaptation (CA2) in factors such as citric acid percentage, maturity index and mechanical damage in comparison with the other containers studied. It is concluded that the implementation of adaptations to the plastic basket can reduce losses caused during tomato transport between 9% and 9.7%, as well as maintain the physical, physiological and physicochemical properties of the tomato.
Attitudes towards and readiness to involve in protection of natural resources: the case of Gauja National Park inhabitants
Authors:   University of Latvia, Felcis Renars
Published: February 2024

The protection of natural resources during an ongoing climate crisis can be viewed not only as a precondition for natural ecosystems but for social and economic ecosystems as well. At the same time, localization of natural resource protection within rural development issues includes the involvement of local inhabitants both in terms of attitude and practical involvement as an important precondition for sustainable regional development. Based on quantitative data gathered from the project "Ready for change? “Sustainable management of common natural resources” this article aims to reveal attitudes towards protection and readiness to involve in the protection of natural resources of Gauja National Park inhabitants. Data from a representative quantitative survey reveal that local inhabitants of Gauja National Park have high expected responsibility from various actors for the preservation and protection of natural resources. Expected responsibility can also be well explained by the concept of shared responsibility. It can also be concluded that there is broad agreement on the representation of interests of local inhabitants in the Nature conservation plan regardless of civic engagement or involvement in the protection of natural resources – either operationalized as involvement intensity in various dimensions of nature protection or in embedded readiness to involve or involvement in nature protection.
External and internal factors for increasing the use of electronic commerce in the SME sector in Latvia
Authors:   Liepaja University, Gudele Ina , Beizitere Ilona ,   Latvia University of Life Sciences and Technologies, Brence Ieva ,   Turiba University
Published: February 2024

Several studies have found that e-commerce can have a positive impact on any type of business. Some surveys show that the use of e-commerce in Latvia is a problem for most companies in the SME sector; however, there is still a lack of in-depth research to justify the directions of action contained in strategic policy documents. The purpose of the article is to provide analysis of external and internal factors that affect the use of electronic commerce in the SME sector. The Analytic Hierarchy Process (AHP) was used to identify the factors that most positively and negatively affect the e-commerce development of companies. Data from the expert survey were used to conduct the analysis with the AHP method. 17 experts from the state administration, academia and the business environment participated in the survey, who assessed the impact of various internal and external factors on the use of e-commerce in companies. Since the application of e-commerce in companies is one of the measures for faster recovery of the state of the national economy, including developing the export of the SME sector in the post-COVID-19 pandemic period, recommendations have been prepared for public and commercial organizations to have a positive impact on the use of e-commerce in SMEs.
The role of circular cumulative causation and economic geography approach in the development of new industries: example of green hydrogen industry evolution in Latvia and Estonia
Authors:   Latvia University of Life Sciences and Technologies, Lejnieks Ilgmars , Pelse Modrite ,   Latvia University of Life Sciences and Technologies
Published: February 2024

The unbalanced development of regions within the European Union (EU) faces challenges for sustainable economic growth opportunities in the future. Uneven scattering of industrial capacities across the EU determines the unequal distribution of wealth among the member states. The EU economy's Green Deal strategy determines the necessity of developing new technologies in both existing industries and developing new ones. The research emphasises two theories concerning territorial development issues. Circular cumulative causation theory and economic geography distinguish the development of industry, especially the manufacturing sector, as a crucial aspect of the economic development of a particular area. The symbiosis of both theories provides guidelines for a balanced approach to territory economic development capabilities in light of industry sustainability requirements in the present-day economy. The purpose of the study is to evaluate the combined circular cumulative causation and economic geography theory analysis approach by comparing the potential for the development of the green hydrogen industry in Latvia and Estonia. Hydrogen is one of the most likely energy sources to replace fossil fuels in the coming decades, and it possesses high potential for transportation, manufacturing, energy supply, and other sectors of the economy. The study established the research pattern within theoretical bases and identified general trends concerning an assessment framework, which can lead to unbalanced values in the industry’s potential evaluation process. The findings of the evaluation of the green hydrogen industry indicate Estonia's slight advantage over Latvia.
Municipal environmental governance in Latvia: Governance instruments’ framing practice
Authors:   University of Latvia, Ozolins Maris , Biezina Liga ,   University of Latvia, Zilniece Ilga ,   University of Latvia, Ernsteins Raimonds ,   University of Latvia
Published: February 2024

There is a certain positive development in Latvia, especially in particular cases, but, in general, not all environmental governance issues are regularly and sufficiently integrated into Latvian municipal development governance/planning system, since being neither substantially supported by national governance level nor everywhere taking place at the municipal planning and management self-designed practice, particularly, as instant public pressure and requirements are often limited. After governance landscape changing administrative-territorial reform (2021) in the country, researchers now were aiming to study governance dimensions’ framework in municipal practice – studying governance triple dimensions as content, stakeholders, and governance instruments. Research-and-development framework has been applied, using case study research methodology, based on the analysis of documents, general municipal practice structural overview, additional expert interviews/consultations, and, three chosen detailed municipal best practice case studies in Ventspils, Kekava and Valmiera municipalities with complementary governance approaches. Based on these studies, as well as on national previous studies and international best practice comparisons, there are emphasised the two core preconditions for the improvement of municipal environmental governance in Latvia. Since there is to be seen, that municipal environmental governance comprehensive integration approach, being theoretically well thought, but is having only limited success in current pragmatic municipal practice, there is to be secured municipal task-related vertical institutional environmental governance system, covering all four inner municipal administration levels. In parallel with statutory organized ground level environmental sector municipal companies, so-called communal services (drinking/sewage water, energy/heating, sanitary etc. basic environmental sub-sectors), other and newly growing environmental governance content issues are to be also institutionalised, but at the higher local government administration and decision-making levels. Next core precondition - municipal environmental communication complementary instrumentalisation and structural development, including environmental information, education/training, involvement/participation, and pro-environmental behaviour. These improvements would provide the necessary systemic overview and co-management of the whole complexity of environmental governance processes and procedures.
Conceptualization and process simulation of a CO2-based methanol production plant
Authors: Khawaja Saman , Usman Muhammad , Aslam Rabya
Published: February 2024

The present study conceptualizes and simulates a methanol production process through the direct hydrogenation of captured CO2. CuO/ZnO/ZrO2 was employed as the catalyst and Aspen HYSYS was used for the process simulation. Configurational optimization of the process flowsheet was carried out using a step-by-step hierarchical approach. Many alternate flowsheets have resulted, and their capital investment, product cost, and profitability measures were calculated. The discrimination among the competing flowsheets was carried out based on net profit and percent return on investment. The retained flowsheet was further analyzed for optimizing the recycle ratio and evaluating the effect of the price of captured CO2, green H2, natural gas (fuel), and catalyst on the economic performance of the plant. The optimum value of the recycle ratio was computed to be 4.23. Additionally, it was found that the price of H2 is the most important parameter in defining the feasibility and profitability of the process. Mathematical correlations were also developed that relate the profitability and price of the above-mentioned feed materials.
Inspira 3 2015
Authors: Leonardsen Ann-Chatrin Linqvist
Published: February 2024

Dette er en fulltekst av tidsskriftet Inspira nummer 3, 2015. Merk at tidsskriftet publiseres av Cappelen Damm Akademisk fra og med 15. januar 2021. Tidsskriftet ble godkjent som vitenskapelig publiseringskanal i november 2018.
Innhold
Leder: Therese og Sigbjørn
Ebola respons: Åge Wiberg Bøyum og Anne Kristin Jensen
Lyse Lene til minne
Bokanmeldelse
«Fra fjord til fjell» Fagkongress i Ålesund feiring av ALNSF 50 års-jubileum: Ellen Marie Lunde, redaksjonsmedlem Inspira
Avitetskalender
Den overvektige intensivpasienten: Viktoria Mari Markussen
NSFLIS fagkongress i Drammen 23. - 25. September: Anne-Mette Nygaard og Gerd M. Bjørknes
Årets intensivsykepleier: Britt Elin Fredriksen: Nominert av ansatte på Thoraxkirurgisk intensiv 1 og 2 på Rikshospitalet
På tur med Hurtigruta til Ålesund for å delta på ALNSFs fagkongress: Arnhild Lindegaard og Trine Karlsen
ALNSF – nytt
NSFLIS – nytt
Inspira 1 2016
Authors: Leonardsen Ann-Chatrin Linqvist
Published: February 2024

Dette er en fulltekst av tidsskriftet Inspira nummer 1, 2016. Merk at tidsskriftet publiseres av Cappelen Damm Akademisk fra og med 15. januar 2021. Tidsskriftet ble godkjent som vitenskapelig publiseringskanal i november 2018.
Innhold
Leder: Therese og Sigbjørn
Støy i intensivavdelingen -på godt og vondt: Turid Wigtil og Christine Wadel
Nytt sykehus i Østfold: splitter ny operasjonsavdeling på Kalnes: Mia Ulfeldt
Organdonasjonsprosessen -intensivsykepleieres opplevelse: Sigrid Norli Haugerud
Aktivitetskalender
Sjekklister -til begjær eller besvær?: Hilde V. Wæhle, Anette Storesund, Eirik Søfteland og Arvid S. Haugen
Verden samles rundt perioperative sykepleiere: Anne Kath Knudsen
ALNSF – nytt
NSFLIS – nytt
Inspira 2 2017
Authors: Leonardsen Ann-Chatrin Linqvist
Published: February 2024

Dette er en fulltekst av tidsskriftet Inspira nummer 2, 2017. Merk at tidsskriftet publiseres av Cappelen Damm Akademisk fra og med 15. januar 2021. Tidsskriftet ble godkjent som vitenskapelig publiseringskanal i november 2018.
Innhold
Leder: Therese og Sigbjørn
Redaktør med doktorgrad: Ellen Marie Lunde
Bruk av muskelrelaksantia, overflateanestesi eller dyp anestesi ved intubasjon?: Hanne Stålsett og Heidi Svendsen
Minneord om Gerd Margrethe Bjørknes: Fra kolleger
Prehospital identifisering og behandling av hjertestans forårsaket av hypotermi: Maria Blomberg og Ann-Chatrin Leonardsen
Aktivitetskalender
Søvn på dagsorden: Inger-Lise Stene-Nilssen, Therese Bro, Fang Reitanog Ann-Cathrin Linqvist Leonardsen
ALNSF Lokalgruppeleiarkonferanse (LGK) våren 2017: Jannicke Skodjereite
ALNSF – nytt
NSFLIS – nytt
Inspira 4 2017
Authors: Leonardsen Ann-Chatrin Linqvist
Published: February 2024

Dette er en fulltekst av tidsskriftet Inspira nummer 4, 2017. Merk at tidsskriftet publiseres av Cappelen Damm Akademisk fra og med 15. januar 2021. Tidsskriftet ble godkjent som vitenskapelig publiseringskanal i november 2018.
Innhold
Leder: Therese og Paula
Skriveseminar på Lesvos: Sigbjørn Flatland
Sepsis hos eldre: Maria Thune og Ann-Chatrin Leonardsen
Antikoagulasjonsbehandling og akutt kirurgi: Kristoffer Andresen, Dan Atar, Erik Gjertsen, Svein Roseth, Odd Erik JohansenBoehringer Ingelheim
Doktorgrad om smerter hos intensivpasienter: Vivian Nystrøm
Hva Mastergradskompetanse kan bidra med i klinisk praksis: Bente Skogaas og Berit Taraldsen
Aktivitetskalender
Polynevromyopati hos intensivpasienter: Linh My Chau, Anne-Mette Nygaard, Ann-Chatrin Leonardsen
ALNSF – nytt
NSFLIS – nytt
Inspira 1 2018
Authors: Leonardsen Ann-Chatrin Linqvist
Published: February 2024

Dette er en fulltekst av tidsskriftet Inspira nummer 1, 2018. Merk at tidsskriftet publiseres av Cappelen Damm Akademisk fra og med 15. januar 2021. Tidsskriftet ble godkjent som vitenskapelig publiseringskanal i november 2018.
Innhold
Leder: Therese og Paula
Hjerneoperasjon i våken tilstand: Anders Aasheim
Bruk av endotrakealtube med subglottis-sug kanforebygge ventilatorassosiert pneumoni: Elin Munch, Anne-Mette Nygaard og Ann-Chatrin Leonardsen
Overfylt urinblære – vårt ansvar!: Kirsten Marie Eliassen, Hilde-Irén Liland og Sylvin Thomassen
Overvekt og forebygging av atelekaser: Malin Mikaela Persdotter Myhren
Pårørende til intensivpasienter: Gro Frivold
Derfor virker sjekklister!: Hilde V. Wæhle, Eirik Søfteland og Arvid S. Haugen
Aktivitetskalender mars 2018
Motivasjon til å skrive fag- eller forskningsartikkel
ALNSF – nytt
NSFLIS – nytt
Inspira 2 2018
Authors: Leonardsen Ann-Chatrin Linqvist
Published: February 2024

Dette er en fulltekst av tidsskriftet Inspira nummer 2, 2018. Merk at tidsskriftet publiseres av Cappelen Damm Akademisk fra og med 15. januar 2021. Tidsskriftet ble godkjent som vitenskapelig publiseringskanal i november 2018.
Innhold
Leder: Therese og Paula
Hvordan ivareta pårørende ved organdonasjon?: Hege Ruud Kristiansen, Anette Markussen, Anne-Mette Nygaard, Ann-Chatrin Linqvist Leonardsen
Optimal bruk av trygg kirurgi sjekkliste?: Pernille Nordli, Silje Victoria Bakkenget, Ann-Chatrin Leonardsen
Til minne om Are J. Stegane: Bente Lüdemann
EEG – anestesiens glemte primærparameter?: Anders Aasheim
Slik kan sykepleiere forebygge lungekomplikasjoner: Elin Riis, Hege Jorde
Intensivsykepleiere kan forebygge PTSD: Martine Mathisen, Anne-Mette Nygaard Ann-Chatrin Linqvist Leonardsen
Aktivitetskalender juni 2018
ALNSF – nytt
NSFLIS – nytt
Ambulanseoverføring av pasienter mellom sykehus
Authors: Omnø Raymond Kvalfors
Published: February 2024

Transportmedisin er ikke et eget medisinsk fagfelt i Norge og faller gjerne under kategorien ambulansetjeneste prehospital tjeneste, til tross for at den korrekte benevnelsen er interhospital. Å flytte pasienter fra ett sykehus til et annet innebærer å utsette dem for masse påkjenninger.
Delirium hos intuberte intensivpasienter
Authors: Halvorsen Hedda Teig , Hammer Sandra Karoliussen , Nystrøm Vivian , Leonardsen Ann-Chatrin
Published: February 2024

Delirium oppstår oftest etter kirurgi og under intensivbehandling, og er en akutt forvirringstilstand på grunn av forstyrrelser i hjernens funksjoner. Patofysiologien er uklar, men delirium har en identifiserbar organisk årsak. Forløpet er fluktuerende og kan utvikle seg over tid. Symptomene kan være desorientering, hukommelsessvikt, hallusinasjoner og persepsjonsforstyrrelser (1). Pasientene blir svært sårbare fordi de har redusert evne til å ta del i, påvirke, eller kontrollere egen situasjon (2).
Intensivmiljøet inneholder fysiske, psykiske og miljømessige faktorer som kan utløse et delirium, for eksempel respiratorbehandling, sedasjon, alvorlighetsgrad av kritisk sykdom, mangel på døgnrytme og farmakologisk påvirkning. Predisponerende faktorer som demens eller kognitiv dysfunksjon, depresjon, alvorlig sykdom eller komorbiditet er også tilstede hos pasienten før sykehusinnleggelse (3, 4). Det er rapportert om delirium hos nær 87% av alle respiratorbehandlede pasienter. Ubehandlet delirium kan påvirke pasientens kliniske tilstand, og føre til redusert kontinuitet i behandlingen, lengre behandlingstid, økte kostnader og i verste fall økt mortalitet (5).
Pasientens adferd deles inn i hyperaktivt og hypoaktivt delirium, eller en kombinasjon av begge tilstandene. Hyperaktivt delirium er klassisk beskrevet som at pasienten er aggressive og utagerende, og ute av stand til å samarbeide. Hypoaktivt delirium viser seg ved svekket oppmerksomhet og bevissthet, og nedsatt psykomotorisk aktivitet. Det er høyest forekomst av pasienter i hypoaktivt delirium. På grunn av vage symptomer er det vanskeligere å avdekke. Dette fører til at langtidsprognosen for pasienter med hypoaktivt delirium er dårlig (5, 6).
Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) er et validert kartleggingsverktøy som benyttes for å avdekke tilstanden hos intuberte pasienter som ikke kan kommunisere verbalt (4, 7, 8). Rutinemessig screening med et slikt kartleggingsverktøy for å avdekke delirium er anbefalt. Likevel viser forskning at tilstanden er underdiagnostisert (9, 10).
Mobilisering av intensivpasienter
Authors: Fjerdingby Tine , Nystrøm Vivian , Leonardsen Ann-Chatrin
Published: February 2024

Mobilisering av intensivpasienter kan gi mange gunstige effekter, som forebygging av delir, styrking av muskler, skjelett, sanser og immunapparat, samt forebygging av nevromuskulær dysfunksjon. Dette medfører blant annet redusert liggetid i intensivavdeling og i sykehus (1-3). Komplikasjoner til mobilisering oppstår sjeldent, men når de oppstår er desaturasjon og hemodynamiske komplikasjoner de vanligste (4, 5). Mobilisering innenfor intensivbehandling er definert som alt fra passiv bevegelse ved sengeleie, leieendringer i seng / forflytning, og til aktiv mobilisering der pasienten er deltagende i forbindelse med aktivisering, forflytning eller er stående/ gående (6). Det er internasjonal konsensus om at mobilisering innen 48 timer er trygt og gjennomførbart, også for intensivpasienter (4). Likevel viser studier at intensivpasienter sjelden mobiliseres (1, 3).
Internasjonalt er det utarbeidet ulike retningslinjer som kan bistå behandlingsteamet ved vurdering av om mobilisering er trygt for den enkelte pasient. Det påpekes i retningslinjene at disse må brukes med utgangspunkt i klinisk skjønn og/ eller individuell tilpasning (4, 7). De fleste retningslinjene omhandler hovedsaklig den intuberte intensivpasienten, og ingen av dem forholder seg kun til ikke-intuberte pasienter.
Det finnes lite forskning på mobilisering av ikke-intuberte intensivpasienter.
Mobilisering av intens ivpasienter Tine Fjerdingby t.i.fjerdingby@gmail.com Vivian Nystrøm vivian.nystrom(at)hiof.no Ann-Chatrin Leonardsen ann.c.leonardsen(at)hiof.no Mobilisering hos disse pasientene er essensielt for å forebygge intubasjon, i tillegg til andre kjente komplikasjoner relatert til intensivoppholdet (8). Med utgangspunkt i sin tilstedeværelse 24/7 spiller intensivsykepleiere en sentral rolle ved observasjon, vurdering og mobilisering av intensivpasientene.
Inspira 3 2019
Authors: Leonardsen Ann-Chatrin Linqvist
Published: February 2024

Dette er en fulltekst av tidsskriftet Inspira nummer 3, 2019. Merk at tidsskriftet publiseres av Cappelen Damm Akademisk fra og med 15. januar 2021. Tidsskriftet ble godkjent som vitenskapelig publiseringskanal i november 2018.
Innhold
Redaktøren uttaler seg: Ann-Chatrin Leonardsen
Delirium ved hoftebrudd: Ingvild Marie Stene-Johansen, Madeleine Hagelund Horne, Egil Bekkhus, Ann-Chatrin Leonardsen
Hyperoksi hos premature: Ann Christin Skrøder, Stine Michalsen, Vivian Nystrøm, Ann-Chatrin Leonardsen
Bruk av NIV til ekstuberte pasienter: Therese Winsvold, Mina Eriksen, Vivian Nystrøm, Ann-Chatrin Leonardsen
Fagkongress for anestesisykepleierne i Kristiansand: Ann-Chatrin Leonardsen
NSFLIS fagkongress på Hamar: Brita Fosser Olsen, Anne Mette Nygaard
HEPATISK ENCEFALOPATI: Øyvor Talåsen, Ann-Chatrin Leonardsen
Bruk av Bispectral index for å unngå awareness: Ingunn Lieng, Camilla Kohlstrunk, Ann-Chatrin Leonardsen
Inspira 4 2019
Authors: Leonardsen Ann-Chatrin Linqvist
Published: February 2024

Dette er en fulltekst av tidsskriftet Inspira nummer 4, 2019. Merk at tidsskriftet publiseres av Cappelen Damm Akademisk fra og med 15. januar 2021. Tidsskriftet ble godkjent som vitenskapelig publiseringskanal i november 2018.
Innhold
Redaktøren uttaler seg: Ann-Chatrin Leonardsen
Ambulanseoverføring av pasienter mellom sykehus: Raymond Kvalfors Omnø
Mobilisering av intensivpasienter: Tine Fjerdingby, Vivian Nystrøm, Ann-Chatrin Leonardsen
Delirium hos intuberte intensivpasienter – intensiv sykepleieres erfaringer: Hedda Teig Halvorsen, Sandra Karoliussen Hammer, Vivian Nystrøm, Ann-Chatrin Leonardsen
Fagfellevurdert artikkel: Uhøflighet på operasjonsstua – anestesi sykepleieres erfaringer: Linda Bailey, Simen A. Steindal, Alfhild Dihle
Observasjonsskjema for måling av ISBAR
Authors: Tangvik Linda Skaug , Kinn-Mikalsen Mats A. , Johnsgaard Tone , Reime Marit Hegg
Published: February 2024

Bakgrunn: Oppsummert forskning rapporterer mangelfulle rutiner ved intrahospitale overflyttinger. Den muntlige overleveringen av pasientinformasjon mellom avdelinger beskrives som ustrukturert og varierende, og det etterlyses en standardisering for å øke pasientsikkerheten. ISBAR, anbefalt av Verdens Helseorganisasjon, har i økende grad blitt tatt i bruk av helsepersonell internasjonalt. Kommunikasjonsverktøyet bidrar til systematisk overlevering av pasientinformasjon, og studier viser at bruken kan forbedre kommunikasjonen mellom helsepersonell og redusere uønskede hendelser. Fra 2017 har flere norske sykehus innført ISBAR etter anbefaling fra Helsedirektoratets pasientsikkerhetskampanje ”I trygge hender 24-7”. Ved implementering av ny kunnskap er det nyttig å måle etterlevelsen av denne i klinisk praksis. Et observasjonsskjema som måler bruk av ISBAR ved pasientoverflyttinger mellom en intensivavdeling og medisinske sengeposter ble derfor utviklet og innholdsvalidert til en norsk observasjonsstudie.
Hensikt: Denne metodeartikkelen tar for seg innholdsvalidering av et observasjonsskjema som måler bruk av kommunikasjonsverktøyet ISBAR ved pasientoverflytting fra intensivavdelinger til medisinske sengeposter. Hensikten er å beskrive fremgangsmåten for innholdsvalidering av observasjonsskjemaet, og formidle resultatet av valideringen.
Metode: Observasjonsskjemaet ble innholdsvalidert ved bruk av Content validity index (CVI). Ekspertpanelet bestod av syv intensivsykepleiere og syv sykepleiere som ble rekruttert fra medisinske sengeposter og intensivavdelinger på ett regionsykehus og to lokalsykehus.
Resultater: Ekspertpanelet vurderte den umiddelbare validiteten til skjemaet som god, og at skjemaet målte det som forskerne ønsket å undersøke. Etter innholdsvalidering ble 26 av 29 observasjonspunkter inkludert i det endelige skjemaet, med en S-CVI på 0,91.
Konklusjon/implikasjon: Resultatet fra valideringsprosessen indikerer en svært god innholdsvaliditet. Observasjonsskjemaet kan benyttes til å måle bruk av kommunikasjonsverktøyet ISBAR i klinisk praksis og være et hjelpemiddel for intensivavdelinger for hva en overflyttingsrapport til medisinske sengeposter bør inneholde. Det er videre behov for å teste observasjonsskjemaet ytterligere i nye utvalg, og å teste skjemaets psykometriske egenskaper.
Intervju med statssekretær Anne-Grethe Erlandsen
Authors: Leonardsen Ann-Chatrin
Published: February 2024

I forkant av pressekonferansen om koronasituasjonen med Helseog omsorgsministeren 2. september sendte undertegnede inn noen spørsmål fra InspirA. Siden spørsmålene var omfattende fikk jeg tilbud om å stille spørsmålene i et intervju med statssekretær Anne-Grethe Erlandsen, noe jeg selvsagt takket ja til. Utgangspunktet var den situasjonen våre anestesi- og intensivsykepleiere har stått og står i under pandemien.
Inspira 4 2009
Authors: Jensvold Karin
Published: February 2024

Dette er en fulltekst av tidsskriftet Inspira nummer 4, 2009. Merk at tidsskriftet publiseres av Cappelen Damm Akademisk fra og med 15. januar 2021. Tidsskriftet ble godkjent som vitenskapelig publiseringskanal i november 2018.
Innhold
Leder: Anne-Marie og Hildegunn
Vil flere anestesisykepleiere i ambulansetjenesten heve kvaliteten?: Trond Jensen
Er palpasjon av cuffpiloten god nok praksis for å måle cufftrykket?: Siv-Berit Heggelund
Intensivpasienters betraktninger om familiens betydning under intensivoppholdet: Kristin Dahle Olsen
En stor takk til Grethe Kjeilen
4th All African Anaesthesia Congress, Nairobi, Kenya: Anne Marie Gran Bruun og Ellen Marie Lunde
Prehospital avansert luftveishåndtering: Arild Eskeland
Norsk feltsykehus i Tsjad: Tone Nordmo og Marit Jørgensen
ALNSF – nytt
NSFLIS – nytt
Inspira 2 2013
Authors: Leonardsen Ann-Chatrin Linqvist
Published: February 2024

Dette er en fulltekst av tidsskriftet Inspira nummer 2, 2013. Merk at tidsskriftet publiseres av Cappelen Damm Akademisk fra og med 15. januar 2021. Tidsskriftet ble godkjent som vitenskapelig publiseringskanal i november 2018.
Innhold
Leder: Marit og Sigbjørn
Å lytte til musikk under lokal anestesi - erfaringer og effekt hos engstelige pasienter: Örjan Trängeberg
Kommentar til artikkelen ”Å lytte til musikk”: Berit Taraldsen Valeberg
Arteriekateter i intensivavdelingen: Julia Blinova Kvernmo
Læring av eget arbeid: Maria Hageskal Lund, Tina Nilsen Henriksen og Elin Opphaug
Hjemme hos oss i Østfold:- en intensivavdeling i stadig endring: Tove Lader
ALNSF – nytt
NSFLIS – nytt
Inspira 2 2014
Authors: Leonardsen Ann-Chatrin Linqvist
Published: February 2024

Dette er en fulltekst av tidsskriftet Inspira nummer 2, 2014. Merk at tidsskriftet publiseres av Cappelen Damm Akademisk fra og med 15. januar 2021. Tidsskriftet ble godkjent som vitenskapelig publiseringskanal i november 2018.
Innhold
Leder: Marit og Sigbjørn
Hemodynamisk overvåkning etter hjertetransplantasjon: Erik Granberg og Gro Anne Lunde
AANA Annual meeting, Las Vegas 10.-13. aug. 2013 “reisebrev”: Kjersti Viken
Pårørendes tilstedeværelse og deltakelse: Nabila Sabab
Anestesi til nyfødte: Line Bolgvåg
Barneanestesikurs i Tromsø: Trine Karlsen
ALNSF – nytt
NSFLIS – nytt
Inspira 4 2014
Authors: Leonardsen Ann-Chatrin Linqvist
Published: February 2024

Dette er en fulltekst av tidsskriftet Inspira nummer 4, 2014. Merk at tidsskriftet publiseres av Cappelen Damm Akademisk fra og med 15. januar 2021. Tidsskriftet ble godkjent som vitenskapelig publiseringskanal i november 2018.
Innhold
Leder: Therese og Sigbjørn
Intensivpasientens søvnkvalitet: Karina Knutsen og Aina Swensson
Varmetiltak kan gi brannskade
Bruk av premedikasjon til barn - til barnets beste?: Synne Bjørnå
NSFLIS fagkongress 24. - 26. September: Simuleringskurs: Helga Freyer
PICC line: Carina Brännström
NUBA - Nordisk Utdannelse i Barneanesti for Anestesisykepleiere
En av få utvalgte (så langt): Gry Akre Sundal og Marit Vassbotten Olsen
Hva er Nursing Activities Scoore - NAS, og hva viser forskningen om nytten av NAS?: Siv K. Stafseth og Diana Solms
En leder gå videre...
ALNSF – nytt
NSFLIS – nytt
«Skolen har jo som mandat å utjevne sosial ulikhet» – lærerpraksis i en utjevningspolitisk kontekst
Authors: Kvaale-Conateh Lamin André , Jobst Solvejg
Published: February 2024

Hensikten med denne artikkelen er å bidra til mer kunnskap om forholdet mellom utjevningspolitikk og lærerpraksis, gjennom å undersøke praksisbeskrivelser fra lærere som er tilknyttet en skoleorientert områdesatsing. Analysefunnene framhever hvordan lærerne står i et spenningsforhold mellom utjevningspolitiske intensjoner, deres tilgjengelige ressurser og opplevde praksisutfordringer, under de krevende omstendighetene som informantene beskriver. I diskusjonsdelen drøftes lærernes utfordringer i lys av den utjevningspolitiske konteksten som de befinner seg i, og hvordan informantene gjennom den politiske innramningen av lærerrollen gir uttrykk for en pedagogisk stigmatisering av elever i området.
English abstract
“Schools Have a Mandate to Equalize Social Inequality” – Teacher Practice in an Equity Policy Context
The purpose of this article is to contribute more knowledge on the relationship between equity policy and teacher practice in Norwegian schools, by studying practice descriptions from teachers who are embedded in an area-based initiative. The analysis shows how the teachers find themselves in a professional predicament between equity policy intentions, their available resources, and challenges, under the difficult circumstances that the informants describe. In the following chapter, we discuss the teachers challenges against the equity policy context in which they find themselves in. We also discuss how the informants through the political framing of the teacher’s role, express a pedagogical stigmatization of pupils in the area.
Anti-SARS-CoV-2 spike antibody response to the third dose of BNT162b2 mRNA COVID-19 vaccine and associated factors in Japanese hemodialysis patients
Authors: Hirai Keiji , Shimotashiro Masako , Okumura Toshiaki , Ookawara Susumu , Morishita Yoshiyuki
Published: February 2024

Background: We assessed the anti-SARS-CoV-2 spike antibody response to the third dose of BNT162b2 mRNA COVID-19 vaccine in Japanese hemodialysis patients and determined factors associated with the anti-SARS-CoV-2 spike antibody titer after the third dose of COVID-19 vaccine. Methods: Overall, 64 patients were enrolled in this single-center, prospective, longitudinal study. Anti-SARS-CoV-2 spike antibody titers were compared between hemodialysis patients and 18 healthcare workers. Multiple linear regression analysis was used to identify factors associated with the anti-SARS-CoV-2 spike antibody titer after the third vaccination. Results: There was no significant difference in anti-SARS-CoV-2 spike antibody titer 4 weeks after the third vaccination between hemodialysis patients and healthcare workers (18,500 [interquartile range, 11,000–34,500] vs. 11,500 [interquartile range, 7,918– 19,500], all values in AU/mL; p = 0.17). Uric acid (standard coefficient [β] = −0.203, p = 0.02), transferrin saturation (β = −0.269, p = 0.003), and log–anti-SARS-CoV-2 spike antibody titer 1 week before the third vaccination (β = 0.440, p < 0.001) correlated with the log–anti-SARS-CoV-2 spike antibody titer 4 weeks after the third vaccination. In contrast, only the log–anti-SARS-CoV-2 spike antibody titer 1 week before the third vaccination (β = 0.410, p < 0.001) correlated with the log– anti-SARS-CoV-2 spike antibody titer 12 weeks after the third vaccination. Conclusion: The anti-SARS-CoV-2 spike antibody titer after the third dose of COVID-19 vaccine was comparable between hemodialysis patients and healthcare workers. Uric acid concentration, transferrin saturation, and anti-SARS-CoV-2 spike antibody titer before the third dose were associated with the anti-SARS-CoV-2 spike antibody titer after the third dose in Japanese hemodialysis patients.
Reformulation and Realization of Unit Crime Liability Theory from the Viewpoint of Corporate Compliance
Authors: Na Jiang
Published: February 2024

Lanzhou Nestle Company is exempted from the criminal responsibility on the grounds of fulfilling the compliance management obligations, but this is not the result of the corporate compliance effect on the identification of unit crime, and should return to the basic theory of unit crime liability theory, in order to clarify the specific path of corporate compliance to prevent the identification of unit crime. Unit crime lies in the essence of compliance responsibility, the objective central liability model in organizational responsibility theory is based on the objective aspect to infer the subjective aspect of the overall organization, and makes a comprehensive evaluation which both conforms to the subjective and objective unifies basic principles of criminal law, also provides concrete and clear solutions for practice. The will of corporate should be divided into direct intention and indirect intention. Corporate compliance has the effect of presuming that the unit does not have the will to indulge criminal behavior, that is, corporate compliance obstructs indirect intention. Based on this, the separation of unit responsibility and natural person responsibility is achieved. According to the basic principles of organizational responsibility and natural person responsibility, corresponding situations should be classified and defined separately. Post compliance can achieve the prosecution of natural persons without prosecuting the unit, and natural persons’ criminal responsibility should be reduced.
Medical Legal Aspects of Expert Investigations in the Crime of Child Kidding
Authors: Rodríguez Jorge Ricardo Romel
Published: February 2024

Infanticide represents the type of homicide that most expresses the cruelty of this crime, the characteristics of this fact demand an expertise of extreme quality due to the constant and rapid changes of traces and evidence useful for subsequent forensic determinations. When the violent death of the product of conception occurs, the medico-legal autopsy becomes the decisive procedure for the case to proceed or not with the accusation, the precision of being born alive is the key determination and at the same time the challenge for the forensic doctors, to specify if there was extrauterine life or not defines in many legislations the status of "person", this is the reason for serious debates that include the scientific, legal, social and religious field. The physical examination of the puérpera, the inspection of the place of the fact by the forensic experts even when the product of conception is in the same and the medico-legal autopsy are the three essential procedures. From the above analysis we propose a guide with practical theoretical elements to be taken into account in the medico-legal action for the investigation of this criminal typology, in addition to specifying the causes and circumstances that mediated in the fact.
Challenges and Innovations in Forensic Identification: Case Study of Decomposed Remains in a Crocodile's Body for Missing Child Identification
Authors: Kalhari Rathnayake Rathnayake Weerakoonge Ruchira
Published: February 2024

Identifying a missing child from decomposed remains in a crocodile's body poses significant challenges and complexity. Forensic investigations involving human remains within animal’s body can present unique difficulties apart from conventional investigative scenarios. Decomposed remains added an additional layer of difficulty as the digestive process of a crocodile can significantly degrade the body and its features. Forensic anthropology examinations were impeded due to the limited availability of tiny bone samples. In this scenario decomposed bone pieces were the only remaining material for DNA analysis, the choice of an efficient DNA recovery procedure becomes crucial for successful outcome. In the study, prior to the DNA extraction process, a decontamination technique was employed, followed by decalcification method on the bone sample. The resulting, clean and decalcified bone sample was then subjected to extraction using a silica-based method, and the extracted DNA was subsequently typed through STR amplification. The derived DNA profile information from the bone sample pertaining to the child is compared with the profile details of parents for identification purposes.
Intramural and Adapted-Germ Cell Neoplasia In situ
Authors: Bajaj Anubha
Published: February 2024

Germ cell neoplasia in situ emerges as a precursor lesion configuring type II germ cell tumours as testicular seminoma or post-pubertal non-seminomatous testicular germ cell tumours. Lesion is comprised of neoplastic gonocyte-like cells, latent totipotent or naive germ cells with developmental potential situated within ‘spermatogonial niche’ of seminiferous tubules. Germ cell neoplasia in situ delineates an increased incidence with conditions as uncorrected cryptorchidism, ambiguous genitalia, infertility or preceding history of post-pubertal germ cell tumour within contralateral testis. Neoplasm demonstrates aneuploidy or polypoid genotype with additional chromosomal gains as is chromosome 12p upon commencement of neoplastic invasion. Neoplastic cells appear enlarged, atypical, gonocyte-like and are incorporated with abundant, clear cytoplasm, enlarged, hyper chromatic nuclei, coarse nuclear chromatin, angulated cellular margins and prominent nucleoli.