bluuebunny/crossref_metadata_2025 huggingface dataset:
Automation and Machine Learning in Transforming the Financial Industry
Authors:   UST-Global, Inc., Donepudi Praveen Kumar
Published: November 2020

The major purpose of this study was to analyze the influence of machine learning on the digital age, particularly in the field of finance. This study involves the application of machine learning, its challenges, opportunities and effect on job openings and operations. This paper is based on the findings of a qualitative study of the text on the subject of machine learning in finance. The theoretical portion of this paper explores the universal framework, such as the past, existing and the next level of the machine learning, with emphasis on its advantages and drawbacks. The study also examines the global recognition of machine learning in the review of artificially intelligent development and start-ups in European countries. The research methodology used in this study was the evaluation of the qualitative methods in the paper. The study also reviewed twenty electronic records and articles on machine learning in finance. During the research on how computer technology transforms the banking sector, the implementation and impact of artificial intelligence in financing was discussed. Research shows that several financial institutions have significantly benefited from the introduction of a variety of machine learning and artificial intelligence. This paper demonstrates that there is a lack of experience in the field of machine learning, even as many unskilled or semi-qualified tasks carried out by individuals are carried out by machines. This study has shown that, through banking and financial valuation, whether it is manufacturing, data analysis or continuing to invest, there will be many more developments that can get the job done.
Role of Technology in the Development of Smart Cities
Authors: Miah Md. Shelim , Amin Ruhul
Published: November 2020

The key aim of this paper is to address the technical effects of smart city growth. While the smart city issue has been discussed in recent literature, it is of interest if macro ICT considerations should also be considered for determining a city's technical advancement. First of all, literature analysis of a smart city is presented to accomplish this purpose. Along with a theoretical structure focused on the information community, an overview of the smart city idea is included. The ICT development of Smart Cities depends on the characteristics and features of the cities, as well as on macro-technological considerations. Cities that use information technology as a means of urban sustainability build smartness to emerge as smart cities as a source of constant growth and transformation within the urban ecosystem, pursuing a managerial and organizational vision of sustainability. The aim of this thesis is to suggest a theoretical overview of the city as a sustainable society that drives urban development and adopts a smart urban growth vision.
Chemical composition and microbiological quality of bee pollen
Authors: Lorini Alexandre , Rosa Claudineli Cassia Bueno da , Oliveira Livia Teixeira , Wobeto Carmen
Published: November 2020

Besides honey and propolis, bee products already well consolidated, pollen also has relevant economic, nutritional and functional value. As the quality of the final product is directly related to the region where it is collected and processed, this work has evaluated the nutritional and microbiological quality of two dehydrated bee pollens from São Paulo state and the other produced by beekeepers from northern of Mato Grosso state, but with no inspection. Physical-chemical and microbiological quality, phenolic composition and mineral profile analysis were performed. It was observed that both pollens presented satisfactory quality regarding protein contents (24.8 ± 2.4 g 100 g-1), total sugars (36.2 ± 1.1 g 100 g-1), lipids (4.0 ± 0.3 g 100 g-1), ashes (2.6 ± 0.05 g 100 g-1), free acidity (238.7 ± 4.5 mEq Kg-1) and pH (4.8 ± 0.03), however regarding the humidity levels (6.6 ± 2.2 g 100 g-1) both samples were not in accordance with recommended by law (4 g 100 g-1). The bioactive profile has shown a significant amount of phenolic compounds (37.3 ± 1.1 mg GAE g-1) and flavonoids (41.8 ± 2.5 mg QE g-1), besides potential antioxidants around, approximately, 50 and 80%. Microbiological analyzes have revealed low bacterial contamination (≤ 3.6 MPN g-1), molds and yeasts (variation between 1.2x103 and 4x101 CFU g-1), according to values stipulated by the current legislation, being observed the absence of Salmonella sp. and Escherichia coli. The bee pollens investigated have nutritional quality and safety for consumption. However, pollen from São Paulo state showed greater antioxidant potential, probably due to its higher content of phenolics when compared with pollen from Mato Grosso state.
Does split nitrogen application increase garlic yield and quality?
Authors: Besen Marcos Renan , Ogawa Juliano Masahiko , Ribeiro Ricardo Henrique , Guginski-Piva Claudia Aparecida , Piva Jonatas Thiago
Published: November 2020

Nitrogen (N) fertilization is essential for obtaining high garlic yields and satisfying commercial requirements for bulb diameter. However, excess nitrogen may favor the development of lateral shoots. This study aimed to examine the effect of different N application strategies on garlic yield and quality. The experiment was conducted in the field using garlic cv. Chonan and four N fertilization strategies (T1, N fertilizer applied at 15-day intervals; T2, N fertilizer applied before and after clove differentiation; T3, N fertilizer applied before clove differentiation; and T4, N fertilizer applied after clove differentiation). All treatments received the same N rate (210 kg ha-1). A single N application before clove differentiation (T3) favored lateral shoot growth, resulting in the highest incidence of this defect (11.66%). The other treatments did not differ in lateral shoot incidence. Four classes (3–6) of bulb diameter were observed, with treatments ranked in decreasing order as T2 > T1 > T3 > T4. There were no significant differences in garlic yield between single N application treatments (T3 and T4). However, garlic yield differed by 73% between T1 (13,329 kg ha-1) and T4 (7,679 kg ha-1), by 55.31% between T2 (11,927 kg ha-1) and T4, and by 36% between T1 and T3 (9,783 kg ha-1). These results indicate that two N fertilization strategies can be adopted in high-quality garlic production: fortnightly N fertilization or split N application before and after clove differentiation. A single N application is not recommended, regardless of application timing, as it promotes lateral shoot growth and reduces garlic quality and yield.
Characterization of properties and deterioration by termites in the Pinus elliottii Engelm. wood
Authors: Gallio Ezequiel , Costa Henrique Weber Dalla , Guerreiro Laíse , Cruz Nidria Dias , Beltrame Rafael , Gatto Darci Alberto
Published: November 2020

The technological properties of wood are constituted by parameters, which after being analyzed, make it possible to define an appropriate use for this material. However, the deterioration of the wood due to the attack of termites, which find their food source in the chemical components, ends up altering these original technological characteristics, reducing their useful life and compromising their use. Thus, this study aimed to determine some technological properties of Pinus elliottii, as well as to evaluate the influence of deterioration caused by Nasutitermes termites in this wood. Specimens with dimensions of 20 x 20 x 150 mm (tangential x radial x longitudinal) were used as specimens. The physical properties evaluated were the basic density and linear shrinkage (tangential and radial contractions, and anisotropy coefficient), while the mechanical properties were represented through the Janka hardness test and compression parallel to the fibers. After 40 days of the biodeterioration test with Nasutitermes termites, changes in the equilibrium moisture content, retractability, water absorption rate and mechanical properties were evaluated. While the physical and mechanical properties evaluated showed values similar to those found in the literature, the deterioration caused by termites caused a reduction in hardness and parameters related to compression, increasing the dimensional instability of the wood, represented by the variation in the anisotropy coefficient. This made it possible to conclude that the biodeterioration resulting from the attack of termites directly affected the technological parameters of the wood, and consequently, its quality for the use in the purpose it could initially be destined.
Cotton response to nitrogen fertilization in the integrated crop-livestock system
Authors: Steiner Fábio , Zuffo Alan Mario , Silva Kátia Cristina , Machado de Oliveira Lima Isabela , Ardon Hector José Valerio
Published: November 2020

Cotton has been widely cultivated in the Cerrado region, including the crop-livestock integration system under no-till. The objective of this study was to evaluate the effects of plant residues from ruzigrass [Urochloa ruziziensis (R. Germ. C.M. Evrard) Crins] and nitrogen fertilization on nitrogen use efficiency, growth, and yield of cotton crop (Gossypium hirsutum L. R. latifolium Hutch.), cv. TMG 44 B2RF. The experimental design was randomized blocks, in a split plot scheme, with four replications. The plots consisted of three production systems: i) conventional cotton cropping in fallow area; ii) cotton cropping in the presence of straw from the shoots and roots of ruzigrass plants; iii) cotton cropping only in the presence of residues from the ruzigrass roots. The subplots consisted of five rates of N (0, 40, 80, 120 and 160 kg ha–1), applied at 30 and 50 days after seedling emergence. The presence of ruzigrass straw provided less growth and development of cotton, in addition to less N uptake by plants. The cotton cropping in the crop-livestock integration system in the presence of residues from the roots and shoots of the ruzigrass plants resulted in the greater cotton yield in the second year, demonstrating the importance of the straw formation of the cover crops for the sandy soils of the Cerrado region. The optimal application rate of N in topdressing for the cropping of cotton in succession or not with ruzigrass residues in sandy soil varies from 100 to 110 kg N ha–1.
Rock powder and organic fertilization in soil cultivated with black bean
Authors: Gotz Lenir Fátima , Piovesan Felipe , Castamann Alfredo
Published: November 2020

The use of rock powder as a source of nutrients to plants can be an alternative or complement to mineral soluble and organic sources. Thus, the aim of this study was to evaluate the potential of different rock powder doses, associated or not with livestock manure, as a source of nutrients for bean and its effect on soil chemical attributes. The treatments consisted of the application of 0, 3, 6, 9 and 12 Mg ha-1 of rock powder, associated or not with livestock manure (17 Mg ha-1), applied on the soil surface, without incorporation. The experiment was carried out in completely randomized blocks, with three replicates, and in a factorial arrangement (5x2). The grain yield of bean, height plants and number of plants m-2 were not influenced by the treatments. On the other hand, the application of 3 Mg ha-1 of rock powder associated with livestock manure resulted in a higher number of grains per pod, and the increase in the rock powder doses affected the number of pods per plant. In the soil, only the manure application, regardless of the rock powder, resulted in effects: reduced potential acidity and potential cation exchange capacity, and increased phosphorus content and base saturation. Thus, rock powder, associated or not with livestock manure, is not effective in improving bean yield and soil chemical attributes after approximately three months of application, and the use of livestock manure, regardless of the rock powder doses, improves some chemical attributes in the soil.
Egy gyermekcsoport szerepe a családsegítésben részesülő családokban nevelkedő hátrányos helyzetű gyermekek körében 1995–2005 között
Authors: Sik Dorottya
Published: November 2020

The aim of this paper is to analyse the methods and effects of a children group, which existedfrom 1995 till 2005. The relevance of this group is, that the beginning of this period preludes theconstitution of the Hungarian child protection law. After the transmission period the emergingsocial service system provided (or at least tried) supports and services. Those families whosechildren were involved in this child group were dealing with unemployment, poverty, lack ofproper housing, abuse, deviance and addictions. The significance of this group that the givenservice was easily ductile to the needs of the children and families.
THE POSSIBILITY OF PREDICTION OF DENTAL CARIES IN CHILDREN DURING THE PERIOD OF CHANGEBITE
Authors: Mityaeva Tatyana , Skripkina Galina , Ekimov Evgeniy , Matskieva Olga
Published: November 2020

Background. Preventive measures that are implemented through the introduction of regional prevention programs have a massive focus and do not lead to a decrease in dental morbidity, because they are based on routine preventive measures without taking into account the individual characteristics of metabolic processes in the patient's oral cavity. All this confirms the need to abandon the mass approach when carrying out preventive measures, and requires the search for modern methods for predicting dental caries, based on predictive diagnostics of the risk of caries, which should be a key element of clinical examination of the pediatric population by a dentist.

Purpose of the study: on the basis of a comprehensive clinical and laboratory approach with the use of mathematical analysis of the obtained data on homeostasis of the oral cavity, to establish predictors of the development of the carious process in children in order to determine the possibility of predicting dental caries during the period of mixed bite.

Methodology. To achieve this goal, a comprehensive clinical and laboratory examination of metabolic processes in the oral cavity was carried out in 60 caries-resistant children during the period of mixed bite: from 7 to 12 years. Statistical analysis was performed using the STATISTICA 8.0 software.

Results. According to the results of the study, strong relationships were revealed between individual clinical and laboratory indicators-predictors, an optimal set of predictors was established for constructing classification models for patients with different types of MCS, which is a prerequisite for the possibility of predicting the risk of caries development in children during the mixed bite period.

Conclusions. An optimal set of predictors has been established for constructing classification models for patients with different types of ISS for creating computer programs aimed at preclinical diagnostics of the subclinical course of the carious process with access to prediction, which will allow planning individual primary preventive measures in children during the period of active formation of hard dental tissues.
PREVENTION OF TOXIC-ALLERGIC REACTIONS WHEN USING DENTURES AND DEVICES
Authors: Zotov Aleksey , Podoprigora Anna , Komarova Yuliya , Kalivradzhiyan Edvard , Stepanov Ilya , Belenova Irina
Published: November 2020

Subject. Today, nanoparticles of chemical elements that make up the body are of particular interest. Such nanomaterials usually do not cause allergic reactions, they can potentially be broken down and removed from it, and, for example, drugs can be placed in the pores of these materials. At the Department of Prosthetic Dentistry of V.G. N.N. Burdenko together with Voronezh State University developed a polymer modified with nanosized silver particles, which was successfully tested on patients in the manufacture of removable plate prostheses. However, there is no data on the effect of this polymer in patients with complex jaw pathology in combination with somatic pathology, in which visible changes occur in the oral cavity.

Goal ― to consider the problem of prevention of toxic-allergic reactions when using complex-jaw prostheses and devices. To study the state of the oral microbiocenosis and the cytological characteristics of the mucous membrane in patients with apparatus bases made of a polymer modified with nanoscale silver. Materials and methods. 80 people were examined and 60 patients were treated for complete absence of teeth with various degrees of atrophy according to A.I.Doynikov (1967) I, II, III, IV, V, with a uniform quantitative distribution in groups.

Methodology. 80 people were examined and 60 patients were treated for complete absence of teeth with various degrees of atrophy according to A.I.Doynikov (1967) I, II, III, IV, V, with a uniform quantitative distribution in groups.

Results. The dynamics of the inflammatory processes of the mucous membrane of the prosthetic bed under the bases of removable jaw devices made by the known method and with bases from modified materials was studied. A complex of personalized prevention of complications associated with the action of basic polymers has been developed.

Conclusion. Obtained by analyzing the results of the study, it was possible to create, on the basis of the use of modified acrylic polymer as the material of the bases of removable prostheses and devices, a program for individual prevention of the inflammatory complications induced by them from the mucosa of the prosthetic bed, the efficiency level of which is at least 60 %. This predisposes to recommendations for the further implementation of the modified nanosilver acrylic polymer in practical dentistry.
THE RELATIONSHIP OF QUALITY OF LIFE INDICATORS AND PSYCHOLOGICAL STATUS FEATURES IN CADETS OF THE UFA LAW INSTITUTE OF THE MINISTRY OF INTERNAL AFFAIRS OF THE RUSSIAN FEDERATION WITH CHRONIC GENERALIZED CATARRHAL GINGIVITIS
Authors: Sitdikova Olesya , Kabirova Milyausha , Gubina Oksana
Published: November 2020

Subject. Chronic generalized catarrhal gingivitis affects the physical condition of a person, as well as the psychology of their behavior, emotional reactions, as well as their role in social life. Doctors are not always set up to assess the quality of life and patient satisfaction with the therapy. The peculiarity of this disease is the vastness of its clinical manifestations, and the need to start treatment in a timely manner, and patients taking medications themselves, affects poor adherence to treatment. These characteristics have an impact on the quality of life, and if the quality of life improves as a result of therapy, this motivates patients to effectively control their condition.

Goal ― to assess the quality of life, frequency and severity of anxiety and depressive disorders in cadets with chronic generalized catarrhal gingivitis.

Methodology. We conducted a survey of 140 cadets aged 18 to 25 years.

Results.The revealed patterns suggest that bleeding, gum pain,and halitosis often contribute to the clinical manifestation of anxiety and depressive disorders in cadets with chronic generalized catarrhal gingivitis, thereby impairing the quality of life. The combination of various metabolic factors in a closed circle mutually increases the severity of not only clinical manifestations of chronic generalized catarrhal gingivitis, but also affects the mental status of the patient, increasing the degree of neurosis-like manifestations

Conclusion. Chronic generalized catarrhal gingivitis significantly affects the decline in indicators of not only physical health, but also mental well-being. High levels of anxiety and depression are most significantly correlated with indicators of mental and physical health of cadets . Thus, anxiety and depression of a somatogenic nature has a negative impact on the quality of life, aggravates the course of the underlying disease, significantly affecting the General well-being of the patient.
Walki oddziału wydzielonego ppłk. Mariana Frydrycha z jednostkami 30 dywizji piechoty wehrmachtu o utrzymanie przeprawy mostowej w Uniejowie w dn. 6–7 września 1939 roku
Authors: Wójcik Tomasz , Boraś Jacek
Published: November 2020

W czasie wojny obronnej we wrześniu 1939 roku Uniejów i jego okolice były miejscem zaciętych walk pomiędzy oddziałami polskiej armii „Poznań” i niemieckiej 8 armii. Taktyczne znaczenie Uniejowa związane było ze znajdującą się tutaj przeprawą przez rzekę Wartę, której utrzymanie miało kluczowe znaczenie dla wojsk polskich, maszerujących znad granicy w kierunku Warszawy. Wrogie sobie oddziały stoczyły w tym rejonie walkę o utrzymanie przeprawy mostowej (Polacy), bądź jej zdobycie (Niemcy). Bitwa miała miejsce w dniach 6–7 września, gdy polski Oddział Wydzielony ppłk. Mariana Frydrycha, dowódcy 60 Pułku Piechoty Wielkopolskiej z 25 Dywizji Piechoty, uniemożliwił oddziałom 30 Dywizji Piechoty z 8 armii Wehrmachtu zdobycie i zniszczenie mostu w Uniejowie, a tym samym zapewnił bezpieczeństwo przeprawy oddziałom macierzystej armii. Bitwa miała dwie fazy, pierwszą była zasadzka 2 batalionu 60 pp pod Balinem w dn. 6 września wieczorem. Drugą był kontratak sił niemieckich, rozpoczęty następnego dnia rano. Bitwa pod Uniejowem była wstępem do walk tych samych oddziałów pod Łęczycą (I faza bitwy nad Bzurą). Autorzy po raz pierwszy w polskiej historiografii wykorzystują dokumenty dywizyjne z archiwów niemieckich, identyfikując wojska Wehrmachtu, biorące udział w tych walkach, do szczebla pododdziałów oraz prezentując obraz walk z perspektywy wojsk agresora. Udało się także jednoznacznie wyjaśnić nierozstrzygniętą dotąd w piśmiennictwie kwestię rozbicia przez Niemców 1 batalionu 29 Pułku Strzelców Kaniowskich pod Uniejowem 7 września wieczorem.
Implicaciones geopolíticas y económicas del Brexit en la Unión Europea
Authors: Linares Giraldo Maricel , Avendaño Castro William Rodrigo , Mogrovejo Andrade Johanna Milena
Published: November 2020

El objetivo de este artículo de investigación es analizar las implicaciones económicas y geopolíticas del Brexit para la Unión Europea y Gran Bretaña. Corresponde a una investigación cualitativa con alcance descriptivo, enmarcada en el paradigma interpretativo. Se consultaron fuentes documentales para el logro de los objetivos, y la información recolectada fue sometida a un proceso de codificación y categorización a través del software Atlas Ti. Los resultados del análisis permiten exponer los hallazgos en dos apartados: 1) las causas y el proceso del Brexit, haciendo especial alusión a las razones políticas y a los resultados del voto del 2016; 2) los impactos del Brexit de acuerdo con el análisis de la literatura, los cuales se codifican y categorizan para una mejor comprensión del fenómeno. Aunque existe una importante literatura sobre los múltiples y variados efectos del Brexit, solo en los próximos años se podrán reconocer las implicaciones de este fenómeno para los grupos de interés.
Socio-Cultural and Institutional Mechanisms and Resources of Contemporary and Soviet-Era Solidarity Practices (Through the Example of Soviet-Era Patronage and Corporate Volunteering)
Authors:   Institute of Sociology of the FCTAS RAS, Russian Federation, Klimova Svetlana G. , Klimov Ivan A. ,   Institute of Sociology of the FCTAS RAS, Russian Federation
Published: November 2020

This article continues the analysis of the continuity problem with regard to contemporary and Soviet-era solidarity practices as exemplified by patronage and corporate volunteering, which was started in the article published in the Yearbook of the Federal Center of Theoretical and Applied Sociology of the Russian Academy of Sciences in 2019 and was devoted to the theme of meanings and functions of both activities This article analyzes the subjects, resources (organizational, material, and personal) and competencies of both solidarity activities as well as their socio-economic mechanisms. The author draws abconclusion that the organizational orderliness of volunteering is not always sufficient for its social effectiveness. In turn, social effectiveness occurs where absystem of non-random horizontal connections is built and where the interaction of subjects included in volunteer projects is based on local identities and an operational system of social responsibility. Where local interests (ofbauthorities or businesses) supersede the public good, both recipients and donors get disappointed in volunteer projects. The objective of comparing the two social practices is to reveal the theme of the semantic and functional continuity of current solidarity practices and Soviet-era experience (with corporate volunteering and Soviet-era patronage as abspecial case). The application task is to identify sociological parameters of comparison in order to understand what elements of Soviet experience can be used today in doctrinal substantiation and organizational solutions related to volunteering (public and corporate).
Finding Better Job by Employed People as the Feature of Precarious Work
Authors:   Bashkir Branch of FCTAS RAS, Ufa, Russian Federation, Valiakhmetov Rim M. , Turakayev Marcel S. ,   Bashkir Branch of FCTAS RAS, Ufa, Russian Federation, Yelena V. Kabashova ,   Bashkir Branch of FCTAS RAS, Ufa, Russian Federation
Published: November 2020

The article is devoted to the set of signs and consequences of unstable employment, expressed in the desire and readiness to find abnew job with better working conditions. The article identifies two groups of factors that affect the probability of finding another job: 1)ba set of social and labor characteristics; 2)bа personal desire for professional and career growth. The willingness to change the place of work is manifested through the individual response of the working person to the working and living conditions. The search for abbetter job is most often prompted by such undesirable social and labor factors as employment without ablabor contract, underemployment or flexible work schedule, temporary nature of work, availability of additional work and overtime, dissatisfaction with working conditions, lack of labor safety guarantees, discrepancy between the place of permanent residence and the place of work (shift work, pendulum migration), etc. Abstimulating factor in the search for abbetter job is also the desire for professional or career growth. According to our research, employed respondents who believe that their level of education and qualifications allow them to perform more difficult work are more likely to search for another, namely abbetter job.
New Social Elevators in the Regional Space
Authors:   South Russian Branch of FCTAS RAS, Rostov-on- Don, Russian Federation, Volkov Yury G.
Published: November 2020

The problem of new social elevators in Russian society has entered the public space and has become abdiscussion space not only for the expert community, but also for practical managers. It is obvious that the social class and socio-territorial (spatial) barriers to upward social mobility generate abmultiplicative effect of social stagnation. According to the author of the article, new social elevators in the regional space are mechanisms of upward social mobility of subjects of the regional space (volunteer movements, social networks, subcultural practices), focused on changes in social status positions according to the criteria of social utility, social creativity, and social self-determination. Applying the principles of the resource approach (volume of capital, diversity capital, resource potential regional space, resursoemkost regional elite and non-elite actors of the regional space) on the basis of the results of all-Russian and regional sociological researches devoted to different aspects of the problem, it is concluded that the formation of abnew social mobility is the result of ab“social contract” with regional elites focus on social “capitalization” and the regional space, forming new social elevators within the framework of converting social and cultural-symbolic capital not for inclusion in regional elites, but for acquiring abresource of influence on making vital decisions for regional development.
Impact of personality traits on prosthodontic patients
Authors: Dantas Fernando Filipe dos Santos , Almeida Carlos Emanuel Natividade Ferreira de , Correia André Ricardo Maia , Reis Campos José Carlos
Published: November 2020

Determining oral health-related quality of life in elderly patientswith removable prostheses who have increased difficulty inreporting oral issues is imperative for a successful rehabilitation.Aim: Our objective is to assess the extent to which a trace,or personality dimension, can influence oral health-relatedquality of life (OHRQoL) in rehabilitated patients. Methods:135 participants rehabilitated with removable prosthesis wereevaluated in the Clinical Unit of Removable Prosthodontics ofthe Faculty of Dental Medicine of Porto University, Portugal. TheOral Health Impact Profile (OHIP-14) questionnaire was appliedto evaluate oral health-related quality of life, along with theEysenck Personality Inventory (E.P.I.) to determine a personalitytrait. Statistical analysis was carried out using Mann-Whitney,Student’s t-test, Spearman’s rho and linear regression. Results:No statistical correlation was found concerning age, gender andoral health-related quality of life. Regarding the latter, the highestagreement was found on the question involving “pain in teeth”.The prevalence of acrylic partial dentures, as opposed to partialdentures with metallic framework, was substantially higher. Nosigniﬁcant association between both extraversion/neuroticism(E.P.I.) and oral health-related quality of life (OHIP-14) uponrehabilitation with removable prostheses was found (p>0,05).In our study, personality traits neuroticism and extraversion didnot influence oral health-related quality of life with removableprostheses. However, we should not overlook the importance ofother psychological factors (such as motivation or perception)and their role in determining oral health-related quality of life.Conclusion: Personality traits “extraversion” and “neuroticism”did not influence oral health-related quality of life.
Pelanggaran Hak Anak yang Berkonflik Dengan Hukum Dalam Proses Penyidikan
Authors: Saraswatie Fariza
Published: November 2020

Kasus mengenai Pelanggaran Hak Anak di Indonesia kini semakin meningkat, pada dasarnya banyak aparat penegak hukum yang kurang memahami pengaturan mengenai Hak-hak Anak dalam Undang-Undang No. 11 Tahun 2012 tentang Sistem Peradilan Pidana Anak (SPPA), telah ditetapkan bahwa Hak Anak mempunyai pengaturan yang khusus di dalam proses beracara yang wajib memperhatikan kepentingan terbaik bagi si anak. Dari interpretasi tersebut menjelaskan bahwa Pelanggaran Hak Anak bertentangan dengan pernyataan di dalam Undang-undang tersebut. Penelitian ini menggunakan metode yuridis normatif dengan melalui pendekatan perundang-undangan dan pendekatan konseptual. Pendekatan ini berusaha menjawab terkait akibat hukum pelanggaran hak anak dalam proses penyidikan. Dan peran pemerintah disini sebagai penjamin terpenuhinya hak anak yang berdasar pada peraturan perundang-undangan dan penegak hukum (penyidik) juga harus memperhatikan kode etik profesi kepolisian dalam menjalankan proses beracara khususnya penyidikan yang bersangkutan dengan hak anak.
Trends and Patterns of The Internet Use During School Holidays
Authors: Khalid Khalid , Rozas Indri Sudanawati , Rolliawati Dwi
Published: November 2020

Background: The Internet use according to Indonesian Internet Services Provider Association (APJII) can be an indicator for parents and educators to monitor students’ mental development and learning behaviors.Objective: This study aims to analyze trends and patterns of the Internet use among students during the school holidays.Methods: This study uses data from XYZ operator, one of the most affordable mobile service providers in Indonesia in 2019. The data was analyzed by using Online Analytical Processing (OLAP).Result: The results shows that the use of 3G and 4G data increased significantly during the school holidays, compared to school days. The highest increase of the Internet traffic is during the semester break, occurred at the rate of 22 to 24 hours a day, with the peak reaching 20.87% at 10:00.Conclusion: The research findings can inform relevant parties, both parents and school teachers in guiding their children to use the Internet.
INFLUENCE OF MEDICATION ON FLARE UP AND INFECTION AFTER ELECTIVE ORTHOPEDIC SURGERY IN RHEUMATOID ARTHRITIS PATIENT - A NARRATIVE REVIEW
Authors: Rosadi Yaldi , Marinta Yustin , Afifah Muthiah Nur
Published: November 2020

Background: Orthopedic Surgery in Rheumatoid Arthritis (RA) patients is still controversial between orthopedic surgeons and rheumatologists, mainly due to infection and disease flares. The incidence of postoperative infections may be high due to the immunosuppressive effect of RA medication. Conversely, discontinuance of antirheumatic agents increases the possibility of a disease flare. The objective of our review is to assess the influence of drugs on both incidences.Literature Review: There were 13 studies included in this review. Methotrexate (MTX) is the most common csDMARD option among the included studies. One retrospective study that the incidence of flares tends to be higher among the group of patients who received MTX therapy and stopped more than one week before surgery than the group who did not stop. The use of MTX doses of 5 to 10 mg/week did not show an association with infection or flare incidence. On the use of bDMARD, 37.0% of patients had higher surgical site infection (SSI). Specifically, Tumor Necrosis Factor-alpha (TNF-α) inhibitors significantly (OR: 9.5, 95% CI: 1.0-88.8) increase the incidence of postoperative infections in standard-dose and high-dose, but not significantly in the rate of flares.Summary: csDMARD is recommended for continuous therapy, whereas for bDMARD, although it is recommended for withholding in the perioperative period, the results of the study did not show significant differences. The ideal dosage of medication is by the basic properties of the drug. In comparison, the incidence of flares and infections was significantly higher in biologic than csDMARD.
Profile study of ectopic pregnancy at Department of Obstetrics and Gynecology, Dr. Soetomo Hospital, Surabaya, Indonesia
Authors: Nugraha Andarisa Rachman , Sa’adi Ashon , Tirthaningsih Ni Wajan
Published: November 2020

Objective: Ectopic pregnancy is a leading cause of maternal death during the first trimester of pregnancy, it can cause infertility and even death as a result of massive bleeding of the mother. Based on those fact, study of ectopic pregnancy is needed.Materials and Methods: This study used retrospective design and total sampling to collect the data and present it as a descriptive – analytical result.Results: Of the 98 samples, as many as 30.6% of the patients age was in the range of 26 - 30 years, there was 16.3% of patients with unmarried status, hormonal contraception was more often used by patients than intrauterine device, there were 7% of patients with recurrent ectopic pregnancy, as many as 12.1% of patients had a history of surgery in the abdomen or pelvic area, ectopic pregnancy was most common in first pregnancies, and there were 26.4% of patient found with Infection.Conclusion: Ectopic pregnancy has many risk factors, Ectopic pregnancy could be cause by solely one risk factor or more (multifactorial), The most commonly found risk factor was infection.
Detection and Imaging of Damages and Defects in Fibre-Reinforced Composites by Resonance Magnetic Technique
Authors: Alves Carine , Oliveira Janete , Tannus Alberto , Tarpani Alessandra , Tarpani José
Published: November 2020

Defectively manufactured and deliberately damaged composite laminates fabricated with different continuous reinforcing fibres (respectively, carbon and glass) and polymer matrices (respectively, thermoset and thermoplastic) were inspected in magnetic resonance imaging equipment. Two pulse sequences were evaluated during non-destructive examination conducted in saline solution-immersed samples to simulate load-bearing orthopaedic implants permanently in contact with biofluids. The orientation, positioning, shape, and especially the size of translaminar and delamination fractures were determined according to stringent structural assessment criteria. The spatial distribution, shape, and contours of water-filled voids were sufficiently delineated to infer the amount of absorbed water if thinner image slices than this study were used. The surface texture of composite specimens featuring roughness, waviness, indentation, crushing, and scratches was outlined, with fortuitous artefacts not impairing the image quality and interpretation. Low electromagnetic shielding glass fibres delivered the highest, while electrically conductive carbon fibres produced the poorest quality images, particularly when blended with thermoplastic polymer, though reliable image interpretation was still attainable.
Structure and Biomechanics during Xylem Vessel Transdifferentiation in Arabidopsis thaliana
Authors: Roumeli Eleftheria , Ginsberg Leah , McDonald Robin , Spigolon Giada , Hendrickx Rodinde , Ohtani Misato , Demura Taku , Ravichandran Guruswami , Daraio Chiara
Published: November 2020

Individual plant cells are the building blocks for all plantae and artificially constructed plant biomaterials, like biocomposites. Secondary cell walls (SCWs) are a key component for mediating mechanical strength and stiffness in both living vascular plants and biocomposite materials. In this paper, we study the structure and biomechanics of cultured plant cells during the cellular developmental stages associated with SCW formation. We use a model culture system that induces transdifferentiation of Arabidopsis thaliana cells to xylem vessel elements, upon treatment with dexamethasone (DEX). We group the transdifferentiation process into three distinct stages, based on morphological observations of the cell walls. The first stage includes cells with only a primary cell wall (PCW), the second covers cells that have formed a SCW, and the third stage includes cells with a ruptured tonoplast and partially or fully degraded PCW. We adopt a multi-scale approach to study the mechanical properties of cells in these three stages. We perform large-scale indentations with a micro-compression system and nanoscale indentations through atomic force microscopy (AFM), in three different osmotic conditions. We introduce a spring-based model to deconvolve the competing stiffness contributions from turgor pressure, PCW, SCW and cytoplasm in the stiffness of differentiating cells. Prior to triggering differentiation, cells in hypotonic pressure conditions are significantly stiffer than cells in isotonic or hypertonic conditions, highlighting the dominant role of turgor pressure. Plasmolyzed cells with a SCW reach similar levels of stiffness as cells with maximum turgor pressure. The stiffness of the PCW in all of these conditions is lower than the stiffness of the fully-formed SCW. Our results provide the first experimental characterization of the mechanics of SCW formation at single cell level.
One Step E-Beam Radiation Cross-Linking of Quaternary Hydrogels Dressings Based on Chitosan-Poly(Vinyl-Pyrrolidone)-Poly(ethylene Glycol)-Poly(Acrylic Acid)
Authors: Călina Ion , Demeter Maria , Scărișoreanu Anca , Sătulu Veronica , Mitu Bogdana
Published: November 2020

We report on the successful preparation of wet dressings hydrogels based on Chitosan-Poly(N-Vinyl-Pyrrolidone)-Poly(ethylene glycol)-Poly(acrylic acid) and Poly(ethylene oxide) by e-beam cross-linking in weakly acidic media, to be used for rapid healing and pain release of infected skin wounds. The structure and compositions of hydrogels investigated according to sol-gel and swelling studies, network parameters, as well as FTIR and XPS analyses showed the efficient interaction of the hydrogel components upon irradiation, maintaining the bonding environment while the cross-linking degree increasing with the irradiation dose and the formation of a structure with the mesh size in the range 11-67 nm. Hydrogels with gel fraction above 85% and the best-swelling properties in different pH solutions were obtained for hydrogels produced with 15 kGy. The hydrogels are stable in the simulated physiological condition of an infected wound and show appropriate moisture retention capability and the water vapor transmission rate up to 272.67 g m-2 day-1, to ensure fast healing. The hydrogels proved to have a significant loading capacity of ibuprofen (IBU), being able to incorporate a therapeutic dose for the treatment of severe pains. Simultaneously, IBU was released up to 25% in the first 2h, having a release maximum after 8h.
Associations of Blood Pressure and Heart Rate and Their Contribution to the Development of Cardiovascular Complications and All-Cause Mortality in the Russian Population of 25-64 Years
Authors: Shalnova S. A. , Kutsenko V. A. , Kapustina A. V. , Yarovaya E. B. , Balanova Yu. A. , Evstifeeva S. E. , Imaeva A. E. , Maksimov S. A. , Muromtseva G. A. , Kulakova N. V. , Kalachikova O. N. , Chernykh T. M. , Belova O. A. , Artamonova G. V. , Indukaeva E. V. , Grinshtein Yu. I. , Libis R. A. , Duplyakov D. V. , Rotar O. P. , Trubacheva I. A. , Serebryakova V. N. , Efanov A. Yu. , Konradi A. O. , Boytsov S. A. , Drapkina O. M.
Published: November 2020

Aim. To study the relationship of blood pressure (BP) and heart rate (HR) in a sample of men and women 25-64 years old and their predictive value for the development of fatal and non-fatal cardiovascular diseases (CVD) and mortality from all causes.

Material and methods. Prospective observation was for cohorts of the population aged 25-64 years from 11 regions of the Russian Federation. 18,251 people were included in the analysis. Each participant gave written informed consent. All surveyed persons were interviewed with a standard questionnaire. BP was measured on the right hand with an automatic tonometer. BP and HR were measured twice with an interval of 2-3 min with the calculation of the average value. The patients were divided into 4 groups: the first group with BP<140/90 ><140/90 mm Hg and HR≤80 beats/min; the second group – BP<140/><140/90 mm Hg and HR>80; the third group – BP≥140/90 mm Hg and HR≤80; the fourth group – BP≥140/90 mm Hg and HR>80 beats/min. Risk factors and cardiovascular history were analyzed as well. Deaths over 6 years of follow-up occurred in 393 people (141 – from CVD). Statistical analysis was performed using the open source R3.6.1 system.

Results. A HR>80 beats/min was found in 26.3% of people with BP≥140/90 mm Hg, regardless of medication. Analysis of the associations between HR and BP showed that for every increase in HR by 10 beats/min, systolic BP increases by 3 mm Hg. (p<0.0001). The group with HR>80 beats/min and BP≥140/90 mm Hg had the shortest life expectancy (p<0.001). Adding an increased HR to BP≥140/90 mm Hg significantly><0.001). Adding an increased HR to BP≥140/90 mm Hg significantly worsened the prognosis of patients. Similar results were obtained in the analysis of cardiovascular survival. Elevated BP and elevated HR had the same effect on outcomes, except for the combined endpoint, where the contribution of elevated BP was predominant. However, their combined effect was the largest and highly significant for the development of the studied outcomes, even after adjusting for other predictors. With an increase in HR by every 10 beats/min, the risk of mortality increased statistically significantly by 22%.

Conclusion. The prevalence of HR>80 beats/min in people with BP≥140 mm Hg amounted to 26.34%. Every 10 beats/min significantly increases the risk of mortality by 22%. Increased HR with elevated BP leads to increased adverse outcomes.
Clinical Case of Complicated Thrombophilia in a Patient with Ulcerative Colitis
Authors: Boldueva S. A. , Yarmosh I. V. , Dolinova A. N. , Kaloeva Z. G. , Serkova M. Yu. , Avramova V. M.
Published: November 2020

This article presents the clinical observation of hereditary thrombophilia, complicated by the formation of a thrombus in the cavity of the right ventricle, in a 40-year-old patient with first diagnosed ulcerative colitis. Despite the standard drug therapy, the patient had a persistent fever. Transthoracic echocardiogram revealed a formation in the right ventricle. A differential diagnosis was made between the vegetation and thrombus. Due to the high risk of infective endocarditis, the antibacterial therapy was started. The addition of deep vein and common iliac vein thrombosis required the exclusion of thrombophilia. Molecular genetic testing allowed to diagnose hereditary thrombophilia: heterozygous carriage of mutations in the genes of factor V Leiden, fibrinogen, platelet receptor for collagen, plasminogen activator inhibitor I. The diagnosis of thrombophilia and ineffectiveness of antibacterial therapy led to the conclusion that there was a thrombus in the right ventricle. The treatment of ulcerative colitis was continued. At the same time, anticoagulant therapy was started, and antibiotics were canceled. As a result, clinical remission of ulcerative colitis, regression of venous thrombosis and complete dissolution of the thrombus in the cavity of the right ventricle were achieved. Ulcerative colitis may be complicated by venous trombosis and hereditary thrombophilia increases this risk.
Pharmacokinetics and Pharmacogenetics of Apixaban
Authors: Savinova A. V. , Petrova M. M. , Shnayder N. A. , Bochanova E. N. , Nasyrova R. F.
Published: November 2020

Apixaban is oral anticoagulant, it is widely used in prevention of stroke in non-valvular atrial fibrillation and treatment of deep vein thrombosis and pulmonary embolism. Its main mechanism of action is through reversible inhibition of factor Xa. It specifically binds and inhibits both free and bound factor Xa which ultimately results in reduction in the levels of thrombin formation. Apixaban is mainly metabolized by CYP3A4 with minor contributions from CYP1A2, CYP2C8, CYP2C9, CYP2C19 and CYP2J2 isoenzymes. Some of the major metabolic pathways of apixaban include o-demethylation, hydroxylation, and sulfation, with o-demethylapixabansulphate being the major metabolite. The aim of this review is analysis of associated researches of single nucleotide variants (SNV) of CYP3A5 and SULT1A1 genes and search for new candidate genes reflecting effectiveness and safety of apixaban. The search for full-text publications in Russian and English languages containing key words “apixaban”, “pharmacokinetics”, “effectiveness”, “safety” was carried out amongst literature of the past twenty years with the use of eLibrary, PubMed, Web of Science, OMIM data bases. Pharmacokinetics and pharmacogenetics of apixaban are considered in this review. The hypothesis about CYP и SULT1A enzymes influence on apixaban metabolism was examined. To date, numerous SNVs of the CYP3A5 and SULT1A1 genes have been identified, but their potential influence on pharmacokinetics apixaban in clinical practice needs to be further studies. The role of SNVs of other genes encoding beta-oxidation enzymes of apixaban (CYP1A2, CYP2C8, CYP2C9, CYP2C19, CYP2J2) and transporter proteins (ABCB1, ABCG2) in its efficacy and safety are not well understood, and ABCB1 and ABCG2 genes may be potential candidate genes for studies of the drug safety.