bluuebunny/crossref_metadata_2025 huggingface dataset:
The Benefits of Blockchain Technology for Medical Tourism
Authors: Tyan Inessa , Guevara-Plaza Antonio , Yagüe Mariemma I.
Published: November 2021

The paper discusses the benefits of blockchain technology for medical tourism. The major focus is placed on pre-procedure and post-procedure of medical tourism. The authors argue that blockchain technology can facilitate several stages of medical tourism by enabling disintermediation, allowing cryptocurrency payments, ensuring secure data sharing and privacy, and empowering trusted review systems. With regard to COVID-19 pandemic, the paper outlines the current challenges of the medical tourism industry and prop oses the opportunities for blockchain technology use. The paper attempts to provide important insights regarding the positive implications of blockchain technology use within the medical tourism industry as well as to further advance the current knowledge about blockchain technology’s effects for medical tourism.
Effect of the Influent Substrate Concentration on Nitrogen Removal from Summer to Winter in Field Pilot-Scale Multistage Constructed Wetland–Pond Systems for Treating Low-C/N River Water
Authors: Wang Tao , Xiao Liping , Lu Hongbin , Lu Shaoyong , Zhao Xiaoliang , Liu Fuchun
Published: November 2021

The quality of micropolluted water is unstable and its substrate concentration fluctuates greatly. The goal is to predict the concentration effect on the treatment of nitrogen in a river with an actual low C/N ratio for the proposed full-scale Xiaoyi River estuary wetland, so that the wetland project can operate stably and perform the water purification function effectively in the long term. Two pilot-scale multistage constructed wetland–pond (MCWP) systems (S1 and S2, respectively) based on actual engineering with the same “front ecological oxidation ponds, two-stage horizontal subsurface flow constructed wetlands and surface flow constructed wetlands (SFCWs) as the core and postsubmerged plant ponds” as the planned process were constructed to investigate the effect of different influent permanganate indexes (CODMn) and total nitrogen (TN) contents on nitrogen removal from micropolluted river water with a fixed C/N ratio from summer to winter in the field. The results indicate that the TN removal rate in the S1 and S2 systems was significant (19.56% and 34.84%, respectively). During the process of treating this micropolluted water with a fixed C/N ratio, the influent of S2 with a higher CODMn concentration was conducive to the removal of TN. The TN removal rate in S2 was significantly affected by the daily highest temperature. There was significant nitrogen removal efficiency in the SFCWs. The C/N ratio was a major determinant influencing the nitrogen removal rate in the SFCWs. The organic matter release phenomenon in SFCWs with high-density planting played an essential role in alleviating the lack of carbon sources in the influent. This research strongly supports the rule that there is seasonal nitrogen removal in the MCWPs under different influent substrate concentrations, which is of guiding significance for practical engineering.
A Framework for the Heterogeneity and Ecosystem Services of Farmland Landscapes: An Integrative Review
Authors: Wang Xiaohui , Wu Yao , Manevski Kiril , Fu Manqi , Yin Xiaogang , Chen Fu
Published: November 2021

It is essential for the sustainable development of farmland landscapes to balance ecosystem service trade-offs and improve resource use efficiency during crop production. Thus, an integrative and concept-centric qualitative approach was applied by combining the patch–corridor–matrix model of landscape ecology and the crop layout theory of farming systems into a theoretical framework. The thesis concludes that a farmland landscape comprises three compositions: the crop (the main crop and the service crop), the non-crop, and the non-vegetation, leading to heterogeneous composition and configuration. The main crop, typically displayed as large patches with a high distribution ratio, provides most of the provisioning services, while the service crop performs many regulation services. The non-crop and non-vegetation compositions often appear as strips that can connect different patches as corridors and support the provisioning services of crops. Non-crop compositions mainly focus on support and regulation services, while non-vegetation compositions support farming operations. Further research is needed in several respects, including the ecological impact and ecosystem service trade-offs of the composition and configuration heterogeneity, and strategies for the adoption of cropping systems and agronomic measures at the landscape scale, which are essential to the evaluation, improvement, and redesign of farmland landscapes.
Building Circularity Assessment in the Architecture, Engineering, and Construction Industry: A New Framework
Authors: Zhang Nuo , Han Qi , de Vries Bauke
Published: November 2021

Circular Economy (CE) has proved its contribution to addressing environmental impacts in the Architecture, Engineering, and Construction (AEC) industries. Building Circularity (BC) assessment methods have been developed to measure the circularity of building projects. However, there still exists ambiguity and inconsistency in these methods. Based on the reviewed literature, this study proposes a new framework for BC assessment, including a material flow model, a Material Passport (MP), and a BC calculation method. The material flow model redefines the concept of BC assessment, containing three circularity cycles and five indicators. The BC MP defines the data needed for the assessment, and the BC calculation method provides the equations for building circularity scoring. The proposed framework offers a comprehensive basis to support a coherent and consistent implementation of CE in the AEC industry.
Managing Natural Resources through Sustainable Environmental Actions: A Cross-Sectional Study of 138 Countries
Authors: Lee Tzai-Chiao , Anser Muhammad Khalid , Nassani Abdelmohsen A. , Haffar Mohamed , Zaman Khalid , Abro Muhammad Moinuddin Qazi
Published: November 2021

Management of natural resources is pivotal for sustained economic growth—the increasing ecological footprints causing biocapacity deficit threaten the resource conversation agenda. The study identified the potential causes and consequences of natural resource depletion in a broad cross-section of 138 countries. Ecological footprints, international migrant stocks, industrial value-added, and population growth influenced natural resource capital across countries. The results show that ecological footprints, industrial value-added, and population growth are the detrimental factors of resource capital. In contrast, continued economic growth is helpful to conserve natural resources for future generations. The rise and fall in the natural resource degradation are evident in the wake of international migrants’ stocks to support an inverted U-shaped relationship between them. The Granger causality inferences confirmed the one-way linkages, running from international migrant stocks, economic growth, and population growth to natural resource degradation. It verifies migrants-led, affluence-led, and population-led resource degradation. Ecological footprints Granger causes industrial value-added across countries. The forecasting estimates suggested that economic growth would likely to influenced greater in magnitude to resource degradation by its innovation shocks of 4.791%, followed by international migrant stocks, population growth, ecological footprints, and industrial value added by their innovation shocks of 4.709%, 1.829%, 1.247%, and 0.700%, respectively. The study concludes that international migrant stocks should manage smartly, causing more resource degradation via a channel of increasing biocapacity deficit across countries.
Female Reproductive Health and Exposure to Phthalates and Bisphenol A: A Cross Sectional Study
Authors: Caporossi Lidia , Viganò Paola , Paci Enrico , Capanna Silvia , Alteri Alessandra , Campo Giovanni , Pigini Daniela , De Rosa Mariangela , Tranfo Giovanna , Papaleo Bruno
Published: November 2021

The xenoestrogenicity of some plasticisers (phthalates and bisphenol A) is documented in the literature and may pose a risk to female reproductive health. The aim of this study was to assess exposure to six phthalates. This was achieved by measuring their respective metabolites (mono-ethylphthalate (MEP); mono-n-butylphthalate (MnBP); mono-n-ottylphthalate (MnOP); and monobenzylphthalate (MBzP)), as well as the sum of two of the diethyl-hexyl phthalate metabolites-(∑DEHP) and bisphenol A (BPA) in a female population with infertility problems, and by conducting a correlation analysis between infertility factors, work activities, and lifestyle habits, in order to formulate a causal hypothesis. A cross-sectional epidemiological study was carried out and women under 43 years of age were recruited from an assisted reproduction technology (ART) center; the sample of 186 women was given a specific questionnaire and a spot urine sample was collected. Phthalate metabolites and urinary BPA were analyzed by HPLC/MS/MS. The results showed significantly higher mean values for MEP in women with recurrent pregnancy loss (RPL) (820.5 ± 1929.5 µg/g of creatinine) and idiopathic infertility (230.0 ± 794.2 µg/g of creatinine) than in women with other infertility factors (76.9 ± 171.8 µg/g of creatinine). Similarly, for MnOP levels, women with idiopathic infertility (2.95 ± 3.44 µg/g of creatinine) showed significantly higher values than women with the other infertility factors taken together (1.35 ± 2.05 µg/g of creatinine). Women with tubal factors of infertility, RPL, and endocrine dysfunctions show higher values of DEHP (p = 0.032). Considering occupations, women working in commerce showed more than twice as much urinary BPA levels (1.10 ± 0.48 µg/g of creatinine) compared to women working in other industries (0.45 ± 0.35 µg/g of creatinine). The presence of significantly higher values of certain phthalates, DEHP in particular, especially in women with RPL and idiopathic infertility, suggests a possible involvement of these compounds as competing factors in reproductive issues. The study of sources of exposure suggested that the working activity in trade, as a casher in particular, represents a major one for BPA (p = 0.015).
Trans-Activator Binding Site Context in RCNMV Modulates Subgenomic mRNA Transcription
Authors: Im Jennifer S. H. , Newburn Laura R. , Kent Gregory , White K. Andrew
Published: November 2021

Many positive-sense RNA viruses transcribe subgenomic (sg) mRNAs during infections that template the translation of a subset of viral proteins. Red clover necrotic mosaic virus (RCNMV) expresses its capsid protein through the transcription of a sg mRNA from RNA1 genome segment. This transcription event is activated by an RNA structure formed by base pairing between a trans-activator (TA) in RNA2 and a trans-activator binding site (TABS) in RNA1. In this study, the impact of the structural context of the TABS in RNA1 on the TA–TABS interaction and sg mRNA transcription was investigated using in vitro and in vivo approaches. The results (i) generated RNA secondary structure models for the TA and TABS, (ii) revealed that the TABS is partially base paired with proximal upstream sequences, which limits TA access, (iii) demonstrated that the aforementioned intra-RNA1 base pairing involving the TABS modulates the TA–TABS interaction in vitro and sg mRNA levels during infections, and (iv) revealed that the TABS in RNA1 can be modified to mediate sg mRNA transcription in a TA-independent manner. These findings advance our understanding of transcriptional regulation in RCNMV and provide novel insights into the origin of the TA–TABS interaction.
A Feasibility Assessment of Potential Artificial Recharge for Increasing Agricultural Areas in the Kerbala Desert in Iraq Using Numerical Groundwater Modeling
Authors: Hassan Waqed H. , Nile Basim K. , Mahdi Karrar , Wesseling Jan , Ritsema Coen
Published: November 2021

Groundwater in Iraq is considered to be an alternative water resource, especially for areas far away from surface water. Groundwater is affected by many factors including climate change, industrial activities, urbanization, and industrialization. In this study, the effect of artificial recharge on the quantity of groundwater in the Dibdibba unconfined aquifer in Iraq was simulated using a groundwater modeling system (GMS). The main raw water source used in the artificial recharge process was the reclaimed water output (tertiary treatment) from the main wastewater treatment plant (WWTP) in Kerbala, with 20 injection wells. After calibration and validation of the three-dimensional numerical model used in this study and taking wastewater recharge rates into account, two different scenarios were applied to obtain the expected behavior of the aquifer when the groundwater levels were augmented with 5% and 10% of the daily outflow production of the WWTP in Kerbala. The model matched the observed head elevations with R2 = 0.951 for steady state and R2= 0.894 for transient simulations. The results indicate that the injection of treated water through 20 wells raised the water table in more than 91 and 136 km2 for 5000 and 10,000 m3/day pumping rates, respectively. Moreover, increasing the volume of water added to the aquifer could lead to establishing new agricultural areas, spanning more than 62 km2, extending about 20 km along the river.
Impact of Sediment Layer on Longitudinal Dispersion in Sewer Systems
Authors: Sokáč Marek , Velísková Yvetta
Published: November 2021

Experiments focused on pollution transport and dispersion phenomena in conditions of low flow (low water depth and velocities) in sewers with bed sediment and deposits are presented. Such conditions occur very often in sewer pipes during dry weather flows. Experiments were performed in laboratory conditions. To simulate real hydraulic conditions in sewer pipes, sand of fraction 0.6–1.2 mm was placed on the bottom of the pipe. In total, we performed 23 experiments with 4 different thicknesses of sand sediment layers. The first scenario is without sediment, the second is with sediment filling 3.4% of the pipe diameter (sediment layer thickness = 8.5 mm), the third scenario represents sediment filling 10% of the pipe diameter (sediment layer thickness = 25 mm) and sediment fills 14% of the pipe diameter (sediment layer thickness = 35 mm) in the last scenario. For each thickness of the sediment layer, a set of tracer experiments with different flow rates was performed. The discharge ranges were from (0.14–2.5)·10−3 m3·s−1, corresponding to the range of Reynolds number 500–18,000. Results show that in the hydraulic conditions of a circular sewer pipe with the occurrence of sediment and deposits, the value of the longitudinal dispersion coefficient Dx decreases almost linearly with decrease of the flow rate (also with Reynolds number) to a certain limit (inflexion point), which is individual for each particular sediment thickness. Below this limit the value of the dispersion coefficient starts to rise again, together with increasing asymmetricity of the concentration distribution in time, caused by transient (dead) storage zones.
Factors Controlling Contemporary Suspended Sediment Yield in the Caucasus Region
Authors: Golosov Valentin , Tsyplenkov Anatoly
Published: November 2021

This paper discusses the joint impact of catchment complexity in topography, tectonics, climate, landuse patterns, and lithology on the suspended sediment yield (SSY, t km−2 year−1) in the Caucasus region using measurements from 244 gauging stations (GS). A Partial Least Square Regression (PLSR) was used to reveal the relationships between SSY and explanatory variables. Despite possible significant uncertainties on the SSY values, analysis of this database indicates clear spatial patterns of SSY in the Caucasus. Most catchments in the Lesser Caucasia and Ciscaucasia are characterized by relatively low SSY values (<100–150 t km−2 year−1), the Greater Caucasus region generally have higher SSY values (more than 150–300 t km−2 year−1). Partial correlation analyses demonstrated that such proxies of topography as height above nearest drainage (HAND) and normalized steepness index (Ksn) tend to be among the most important ones. However, a PLSR analysis suggested that these variables’ influence is likely associated with peak ground acceleration (PGA). We also found a strong relationship between land cover types (e.g., barren areas and cropland) and SSY in different elevation zones. Nonetheless, adding more gauging stations into analyses and more refined characterizations of the catchments may reveal additional trends.
Rehabilitation of an Industrial Water Main Using Multicriteria Decision Analysis
Authors: Carriço Nelson , Covas Dídia , Almeida Maria do Céu
Published: November 2021

This paper demonstrates the application of multicriteria decision analysis (MCDA) methodology in a real case study aiming to choose the best rehabilitation intervention of an industrial water main. This methodology is composed of three main stages: problem identification, structuring, and evaluation. Problem structuring, a crucial stage for the outcomes, includes identifying objectives, selecting scenarios within the analysis period, defining problem alternatives, and defining the problematic type. Problem evaluation includes the selection of assessment metrics, selection of the aggregation method, application of the method, and a sensitivity and robustness analysis. Two scenarios, nine assessment metrics, and seven alternatives are established, and two ranking methods (the additive model and ELECTRE III method) are used to compare the alternatives. The results show that the best solution corresponds to building a new pipe and deactivating the existing one, as it significantly reduces the pipe failure risk and O&M costs, whereas the worst solution is always the status quo case, since it is the only alternative that does not improve the system performance, independently of the ranking method and the analyzed scenario.
A Tale of Two Deltas: Dam-Induced Hydro-Morphological Evolution of the Volta River Delta (Ghana) and Yellow River Delta (China)
Authors: Li Dongxue , Gao Weilun , Shao Dongdong , Amenuvor Mawusi , Tong Yao , Cui Baoshan
Published: November 2021

Previous studies mostly focus on an individual delta, or deltas at a global scale, to explore dam effects on deltaic hydrological alteration and morphological evolution, while comparative studies on selected similar deltas remain scarce. In this study, we compare the alteration of river discharge and sediment load, as well as the associated deltaic area and shoreline, of two deltas, namely, the Volta River Delta in Ghana and the Yellow River Delta in China, which are subject to similar forcings and mainstem dam influences. The results show that the sediment loads of the Volta River Delta and Yellow River Delta have decreased abruptly and gradually, respectively, to ~10% of the pre-dam level, presumably due to differences in reservoir capacity and upstream dam location. Sediment decline has led to a decrease of the fluvial dominance ratio, which has also been affected by the river mouth location and shoreline orientation. As a consequence, the area of the Volta River Delta has shifted to a new quasi-equilibrium, whereas the Yellow River Delta has kept prograding. This comparative study provides references for understanding the future evolution of similar deltas around the world.
Current approaches to the treatment of rhinosinusitis
Authors: Gizinger Oksana. A. , Kornova Natalia V. , Beloshangin Artem S.
Published: November 2021

Relevance: despite the available methods and medicines, rhinosinusitis occupies a leading place in the structure of diseases of the upper respiratory tract. Rhinosinusitis can be a consequence of respiratory viral infections, can be an independent nosological unit. In recent years, there has been a protracted course of rhinosinusitis with a long recovery period with chronic inflammation in the paranasal sinuses and nasal cavity. Purpose of the study: to analyze the validity and effectiveness of therapeutic approaches to the treatment of chronic rhinosinusitis using the Polydexa with phenylephrinum nasal spray with phenylephrine Materials and мethods: The study included 121 patients — 61 (50.41 %) women and 60 (49.59 %) men aged 25 to 50 years, a history of chronic rhinosinusitis in the stage of clinical exacerbation at the time of the study. All patients underwent: otorhinolaryngological examination, general clinical and radiological (radiography or computed / magnetic resonance imaging of the paranasal sinuses). Cytological examination of the detachable nasal cavity was carried out to study the calculation of the relative number of neutrophilic granulocytes, macrophages, epithelial cells, lymphocytes. Microbiological examination of the detachable nasal cavity and paranasal sinuses included the study of the qualitative and quantitative composition of pathogenic and opportunistic organisms on the surface of the nasal mucosa. Results: in patients with chronic rhinosinusitis in the stage of clinical exacerbation, an increase in the relative content of inflammatory elements was revealed in the nasal secretion against the background of the prevailing content of pathogenic staphylococci and streptococci. The use of topical preparations containing antibacterial components of a broad antimicrobial spectrum of action, dexamethasone, phenylephrine hydrochloride helps to relieve inflammation on the surface of the mucous membranes of the nasal cavity and paranasal sinuses. Conclusions: a method of treating chronic rhinosinusitis in the stage of clinical exacerbation using a combined preparation for topical application containing neomycin sulfate, polymyxin B sulfate, dexamethasone sodium metasulfobenzoate, phenylephrine hydrochloride has a pronounced anti-inflammatory, decongestant, antibacterial effect
Personal data protection in medical institutions. Part I
Authors: Krylov Aleksandr Petrovich
Published: November 2021

The problem of protecting personal data in medical institutions is currently very acute. The article discusses the main problems of personal data protection.
Generalization of information substantiating the method of subcutaneous administration of recombinant human interleukin-2
Authors: Rybakova Nadezhda Aleksandrovna
Published: November 2021

The article presents the experience and clinical and immunological effectiveness of the use of recombinant human interleukin-2. The accumulated clinical experience of the use of recombinant interleukin-2 in patients of different age groups indicates the validity and expediency of including the drug in the basic therapy of severe bacterial and viral infections, oncological diseases, simultaneously with antimicrobial chemotherapy in order to normalize immunological parameters and improve the clinical course of the disease, as well as for timely and complete resolution of the inflammatory process.
PENGARUH RIWAYAT INFEKSI DAN ASI EKSKLUSIF TERHADAP TUMBUH KEMBANG BALITA DALAM MENCEGAH STUNTING
Authors: Sinaga Elvalini Warnelis , Simamora Debora
Published: November 2021

Stunting is a condition where the toddler's height is less than normal, this is an important problem for Indonesia today. The research method used naturalistic phenomenology with a retrosfective study approach. location in the Kelurahan Pekan Labuhan Medan., a total sample of 50 people, questionnaire interview research instruments. The results showed that there was an effect of infection history and exclusive breastfeeding on toddler growth and development. The results of the statistical analysis of the T test showed that the history of infection had an influence on the growth and development of children under five (p = 0.01; p <0.05), exclusive breastfeeding had an effect (p = 0.02; p <0.05) on the growth and development of children under five. Suggestions for further research with a different design.
HUBUNGAN KARAKTERISTIK IBU BERSALIN DENGAN TERJADINYA RETENSIO PLASENTA DI PUSKESMAS BABUSSALAM KECAMATAN BABUSSALAM KABUPATEN ACEH TENGGARA TAHUN 2021
Authors: Lestari Fika , Cane Purnama Sari , Joharsah Joharsah
Published: November 2021

Causes and post partum bleeding include placental retention which reached 16%-17% in 2016. Placental retention is a condition in which the placenta is not born within 1 hour after the baby is born. The purpose of this study is to find out the relationship between maternal characteristics and the occurrence of placental retention in Babussalam Health Center in 2021. The research was conducted at Babussalam Health Center with a sample number of 22 people with this type of analytical survey research and cross sectional design. The results of the study can be seen with the Chi Square test with a confidence level of 95%, and a = 0.05, based on the parity it is known that X2 calculates > X2 table (14,157 > 7.815) then there is a relationship between parity and the occurrence of placental retention. Based on the age of daketahul X2 calculated > X2 table (13,093 > 5,991) then there is a relationship between the mother's age and the occurrence of placental retention. Based on the state of the uterus known X2 calculates > X2 table (10,092 > 3,841) then there is a relationship between the state of the mother's uterus and the occurrence of placental retention. Based on the sticking of the table is known X2 calculates > X2 table (9,322 > 5,991) it can be concluded that Ha was accepted and Ho was rejected. So there is a relationship between placental attachment and placental retention. There is a characteristic relationship of maternity mothers with the occurrence of placental retention. It is expected to the mother to keep her pregnancy distance and if the mother's age is > 35 years and already have more children and 3 should the mother not get pregnant again because it will be very risky to the mother and fetus.
ADAPTASI PSIKOLOGI KLIEN DENGAN KANKER PAYUDARA DI RS NURUL HASANAH KUTACANE TAHUN 2021
Authors: Nurjannah Nurjannah , Sym Nurhasanah
Published: November 2021

Breast cancer is a disease that can be experienced by women all over the world and affects every aspect of human life, especially psychosocial aspects. The main psychosocial problems experienced by breast cancer clients are ineffective coping, body image and impaired sexual function. This descriptive study aims to identify psychosocial adaptations of breast cancer clients at Nurul Hasanah Kutacane Hospital. The study was conducted from January 12 to June 4, 2021. Determination of the number of samples using total sampling with the number of samples of 25 people. The research instrument used a self-created questionnaire by researchers consisting of demographic data and psychosocial adaptations of breast cancer clients. The questionnaire has been tested for reliability using KR 20 with a result of 0.7029. The results showed that most of the 24 respondents (96%) had adaptive psychosocial adaptations. This research has implications for educational institutions, nursing practices.
HUBUNGAN DUKUNGAN KELUARGA DENGAN KEPATUHAN PASIEN STROKE DALAM MELAKUKAN FISIOTERAPI DI RSUD H. SAHUDIN KUTACANE TAHUN 2021
Authors: Andriani Dina
Published: November 2021

Family support is the help provided by the family to family members in need when facing problems whereas compliance is the extent to which the patient's behavior is in accordance with the provisions provided by the health professional. The design of this study is correlational. The goal is to find out the relationship of family support with the compliance of stroke patients in doing physiotherapy. Sampling using purposive sampling technique amounted to 22 respondents who were a family of stroke patients who did physiotherapy at RSUD Kutacane, Southeast Aceh Regency. The compliance rate of stroke patients in doing physiotherapy in the hospital is about 72.7% where families who provide support as much as 77.3%. Based on the results of the analysis with fisher's exact test obtained the value P (fisher) = 0.000. Then there is a relationship between family support and the compliance of stroke patients in doing physiotherapy. These results show that if the family provides good support, then the patient's compliance with physiotherapy will be better as well. Based on the results of this study, the family should be able to provide support to patients. It is expected that the H. Sahudin of Southeast Aceh Regency Hospital, Educational Institutions and other related institutions will develop a permanent procedure on providing health education to patients and their families, especially about the importance of family support in the recovery of the patient's health.
EFEKTIVITAS PLATELET-RICH PLASMA TERHADAP PERBAIKAN ORGAN GINJAL
Authors: Chiuman Linda , Ginting Chrismis Novalinda
Published: November 2021

Kidney Failure is a health condition that worsen the quality of life. In Acute Kidney Injury and Chronic Kidney Disease there is a damage not only in function but also in the structure of kidney. Platelet Rich Plasma is known to has a lot of benefits as a medical treatment. Platelet Rich Plasma is a plasma that rich in platelets which has the function of regenerating and repairing tissue structures, especially damaged kidneys. This study aimsTo determine the effectiveness of Platelet-Rich Plasma on the improvement of  damaged kidneys. This paper uses a literature study or literature review by searching through Google Scholar or Pubmed using the keywords “Platelet-Rich Plasma”, “Acute Kidney Injury”, “Chronic Kidney Disease” for the last 5 years studies published between 2016 to 2021. Based on the literature search, there were 5 research articles related to the effectiveness of Platelet Rich Plasma on the improvement of damaged kidney, where all studies were tested on experimental animals. Based on the results of the literature study, it can be concluded that there is a relationship between the effectiveness of Platelet-Rich Plasma on the improvement of damaged kidneys in experimental animals.
SUATU STUDI LITERATUR: AKTIVITAS ANTIDIABETIC DARI KULIT JERUK (Citrus sp.)
Authors: Mutia Maya Sari , Ginting Chrismis Novalinda , Yulizal OK
Published: November 2021

Diabetes mellitus is a chronic metabolic disease, which is not able to secrete insulin in sufficient quantities or the body is unable to use insulin effectively so there is an excess glucose level and immediately suffer from some complications against the organs. Diabetes mellitus can be cured by herb utility which are thought to have compounds that has an antidiabetic effect. Therefore, this literature study discusses the antidiabetic activity of orange peel (Citrus sp.). The literature search was carried out on the Google Scholar search engine which used some keyword included antidiabetic, extract, orange peel, Citrus. In this literature study, there are inclusion and exclusion criteria for selecting journals as literature sources. The results of 12 literatures review that orange peel had antidiabetic activity by decrease blood glucose levels in some animal trials that had received an effective dose of orange peel extract in each of the reviewed studies. Hence, it can be concluded that various type of Citrus peels has antidiabetic effect.
Searching for the Roots of Bloom Syndrome Protein and Its Homologs Using Phylogenetic Analysis
Authors: KORAK Tuğcan , KASAP Murat
Published: November 2021

Phylogenetic analysis (PA) is used for elucidation of relationships among different species and provides information about their evolution. BLM protein (BLM RecQ like helicase) is responsible for the repair of stalled replication fork during double-strand break repair by homologous recombination. In the current study, phylogenetic analysis was performed using BLM protein sequences, sequences of its homologs and its putative homologs from 34 species including covering the genera of Bacteria, Archaea and Eukaryotes. This study was carried out for the purpose of (1) illustrating and comparing relationships among eukaryotic BLM proteins, their homologs (ATP-dependent DNA helicase RecQs in Bacteria) and their potential putative homologs (ATP-dependent DNA helicase Hel308s in Archaea), (2) evaluating how BLM protein evolution took place, what it brought to the organisms by acquiring functional changes and how future potential changes would occur and (3) gaining the general perspective in the evolution of BLM protein. All analyzed species in Bacteria, Archaea and Eukaryota formed a clear inter-species cluster, except for P. sinensis (Reptilia). The results supported that Hjm helicase may be one of the candidate potential ancestors of the BLM proteins and their homologs. Moreover, especially two domains which are Helicase ATP-binding and Helicase C-terminal domain were encountered in the all analyzed species and seem to be strictly conserved in the future. Repair related-highly sophisticated interaction network of BLM indicated that its functional evolution reaches a certain level and it appears to have taken an important place in maintaining genomic stability. However, it should be taken into account that BLM may acquire additional functions or become a cornerstone in different pathways in the future depending on its participation in various metabolic roads.
Perbedaan Hasil Belajar Antara Siswa yang Diajar dengan Media Teka-Teki Silang (TTS) dan Lembar Kegiatan Peserta Didik (LKPD) pada Materi Sistem Koloid
Authors: Said Agus , Paputungan Mardjan , Tangio Julhim S.
Published: November 2021

Penelitian ini bertujuan untuk mengetahui perbedaan hasil belajar antara siswa yang diajar dengan model pembelajaran Think Pair Share (TPS) berbantukan media Teka-Teki Silang (TTS) dan Lembar Kegiatan Peserta Didik (LKPD) pada materi sistem koloid di SMA Negeri 4 Gorontalo. Populasi dalam penelitian ini adalah seluruh siswa kelas XI IPA yang terdiri dari 3 kelas dengan jumlah sampel 2 kelas yang masing-masing kelas berjumlah 30 siswa. Desain penelitian ini menggunakan pola rancangan “randomized pretest-posttest comparison group design”. Data hasil belajar kognitif menggunakan tes pilihan ganda, data afektif dan psikomotor menggunakan lembar observasi, uji hipotesis menggunakan uji t. Berdasarkan hasil penelitian dapat disimpulkan bahwa penggunaan model pembelajaran TPS berbantukan TTS memberikan hasil belajar lebih baik dibandingkan dengan penggunaan model pembelajaran TPS berbantukan LKPD baik kognitif, afektif dan psikomotor. Hal ini dibuktikan dengan hasil perhitungan menggunakan uji-t perbandingan antara kedua kelas dengan taraf signifikan 5% diperoleh thitung = 6,530 > ttabel =1,672.
Pengembangan Video Animasi Kimia Terintegrasi Keislaman pada Materi Struktur Atom
Authors: Muslim Buchori , Ramli Munasprianto , Nursarifah Ulfah
Published: November 2021

Abstrak

Penelitian ini bertujuan untuk menghasilkan suatu produk media pembelajaran berupa video animasi kimia terintegrasi keislaman pada materi struktur atom. Proses pengembangan dalam penelitian ini menggunakan model ADDIE yang terdiri dari dari analyze (analisis), design (perancangan), development (pengembangan), implementation (implementasi), dan evaluation (evaluasi). Hasil penelitian uji coba terbatas kepada mahasiswa diantaranya aspek minat terhadap media dengan presentase 84%, aspek penguasaan materi dengan presentase 83,30%, aspek integrasi sains dan islam dengan presentase 86,4%, aspek tampilan dengan presentase 83%, aspek keterlaksanaan dengan presentase 84,7%, serta aspek audio dengan presentase 84,1%. Sehingga secara keseluruhan uji coba terbatas kepada mahasiswa mendapatkan presentase 84,30% dengan kriteria sangat layak. Hasil penilaian produk video animasi oleh ahli media sebesar 82,50% untuk video 1, 83,75% untuk video 2, dan 82,50% untuk video 3. Sehingga video animasi yang dikembangkan dalam penelitian ini mendapat kriteria sangat layak.
Saberes que se privilegian, seguridades que se contabilizan:
Authors: Ocampo Carolina , Blois Paula , Gómez Lilén , Rendón Constanza
Published: November 2021

Durante el 2020 en Argentina se ha desarrollado la peor epidemia de dengue registrada hasta el momento. De manera general, en América esta enfermedad no logra ser prevenida ni controlada. Ante esto, buscamos examinar los sentidos acerca del dengue que circulan entre agentes de salud en un municipio de Buenos Aires (Argentina). El objetivo es comprender qué tipos de saberes y formas de seguridad colectiva configuran las intervenciones contra el dengue en el municipio.
Bitácora cyborg:
Authors: Lodi Maria Eugenia
Published: November 2021

El auge de las tecnologías digitales legitima al ciberespacio y la cibercultura como territorios válidos para el estudio de fenómenos sociales. Nos proponemos vincular el objeto de estudio digital, como problema de investigación y referente empírico, con las transformaciones de la mirada disciplinar, aportar una clasificación de estrategias de estudio de la cibercultura, y abordar la etnografía virtual/digital desde una sistematización de métodos y técnicas de investigación.
Discusiones acerca de la toma de decisiones médicas en el final de la vida:
Authors: Di Marco Martín Hernán , Villarejo Agustina , Alonso Juan Pedro
Published: November 2021

El objetivo de este artículo es analizar la cobertura periodística de los debates sobre “muerte digna” en la prensa escrita Argentina en el período 2011-2015, en ocasión de la discusión y aprobación de la llamada ley de “muerte digna” en el país. Se realizó un relevamiento de noticias en La Nación, Clarín y Página/12 y se conformó un corpus de 373 artículos periodísticos que fueron analizados a partir de un análisis cuantitativo y de análisis temático. En este artículo mostramos cómo la circulación de ideas en torno a la muerte digna se construye a partir de la preeminencia de tópicos legales y familiares, y el poco espacio de abordajes médicos y/o científicos; la centralidad de los estados vegetativos y de los daños neurológicos como condición de salud asociada a estas discusiones, motivada en parte por los casos que pusieron la temática en el ámbito público; el foco de la cobertura en casos emblemáticos y dramas particulares; y, por último, la casi nula referencia a temáticas como la eutanasia o el suicidio asistido en los debates, dominados por la limitación del esfuerzo terapéutico.
Study Of The Effectiveness Of The Use Of Gypsum And Volcanic Ash On Stability Of The Clay Soil Based On The CBR Value And The Unconfined Compression Test
Authors: Lubis Ade Indra Utama
Published: November 2021

Stabilization is one of the efforts to improve the condition of the soil which has a poor index of properties. One of the soil stabilization that is usually done is by adding chemicals to the soil. Chemicals commonly used in the form of cement, lime, bitumen. In this study, the stabilization of clay was carried out by adding gypsum and volcanic ash. The purpose of this study was to determine the value of the index properties due to the addition of 2% gypsum and volcanic ash on the clay soil, then to determine the maximum compressive strength value due to the addition of variations in stabilizing materials by testing the Unconfined Compression Test (UCT) and testing the California Bearing Ratio (CBR). ) laboratory. From the research, it was found that the original soil sample had a moisture content of 12.42%; specific weight 2.65; liquid limit 46.82% and plasticity index 29.40%. The original soil classification according to USCS is classified as Clay – Low Plasticity (CL) and according to AASHTO it is classified as A-7-6 (10). Unconfined Compression Test (UCT) values ​​for native soil and native soil plus 2% gypsum were 1.40 kg/cm2 and 1.66 kg/cm2. The laboratory CBR values ​​for soaked and unsoaked for the original soil were 4.44% and 6.28%, respectively. While the laboratory CBR values ​​soaked and unsoaked for the original soil plus 2% gypsum were 6.74% and 8.02%, respectively.The most effective results were obtained from a mixture of 2% gypsum and 10% volcanic ash with a UCT value of 2.79 kg/cm2 (an increase of 99.28%). For laboratory CBR testing, the most effective mixture was on a mixed variation of 2% gypsum and 9% volcanic ash with laboratory CBR values ​​soaked and unsoaked of 9.07% (an increase of 104.27% from the original soil) and 10 ,29% (an increase of 63.85% from the original land). The soil that has been mixed with the most effective stabilizer material, namely 2% gypsum and 9% volcanic ash is classified as Clay - Low Plasticity (CL) based on the USCS classification and is classified as A-6 (4) based on the AASHTO classification.
Analysis Of The Effect Of Bending Strength On Scaffolding System With Direct Analysis Method
Authors: Talim Michael
Published: November 2021

Steel scaffolding is a very important component in formwork work to support further work. The purpose of this analysis is to review the maximum compressive strength that occurs in 3-story scaffolding before buckling occurs using the direct analysis method (DAM). The design of steel structures, which are generally slender, requires stability analysis. The result is influenced by imperfections (non-linear geometry) and inelastic conditions (non-linear material). In this final project, we use second-order inelastic analysis based on direct analysis method. The 3-level scaffolding model was analyzed using beam elements in the SAP2000 program with 6 variations of notional loads applied to the weak axis direction of the scaffolding pipe.The lowest compressive strength on 3-story scaffolding before buckling occurs is 18.24 kN with horizontal notional loads to the right on the first level scaffolding, left on the second level scaffolding and to the right on the 3rd level scaffolding. The results of the analysis show that the maximum compressive strength obtained results in a large displacement drastically in the iteration step. By using the analysis on the DAM method, the results obtained are more effective.
La educación científica rural en la modalidad m-learning y su afectación en la pandemia de la covid-19
Authors: Rodríguez-Sarmiento Carlos Enrique
Published: November 2021

Desde un aporte científico, social y educativo, este artículo muestra el proceso de enseñanza-aprendizaje de la ciencia física con el modelo M-Learning, además, reflexiona sobre las repercusiones que conlleva la aplicación del modelo educativo durante la pandemia en los estudiantes de secundaria de un colegio público rural de Colombia en dos facetas.

En la primera faceta se evidencia que el M-Learning desde un enfoque constructivista, está llevando la ciencia física con efectividad al lugar donde están los estudiantes y ha contribuido con su posibilidad de aislamiento social, que la Covid-19 sea contenida. En la ruralidad, el teléfono móvil inteligente y la aplicación WhatsApp se destacan por su portabilidad y ventajas económicas.

En la segunda faceta mediante una encuesta virtual se aplica un instrumento de cuatro escalas que miden el ambiente familiar, el ciberacoso, la satisfacción del estudiante y la disposición hacia el estudio. Se encuentra que la disposición para el estudio es explicada por el clima familiar (24%) y por la satisfacción del servicio educativo (51%). La evidencia sugiere que el bienestar estudiantil está siendo afectado por el m-learning en la pandemia repercutiendo en la disposición hacia el estudio, por lo que la educación en el sector rural está involucionando.
PENINGKATAN PEMAHAMAN FIKIH PADA ANAK DENGAN METODE DEMONSTRASI DI MASA PANDEMI COVID-19 DI TPQ AL-HIKMAH KELURAHAN NGRONGGO KOTA KEDIRI
Authors: Khabibi Muhammad Yahya , Surur Agus Miftakus , Subandono Agus
Published: November 2021

Pengabdian masyarakat yang dilakukan ini bertujuan untuk mengenalkan pembelajaran Fikih menggunakan metode demonstrasi sebagai alternatif pengajaran dimasa pandemi Covid-­19. Pengabdian masyarakat yang dilakukan ini berdasarkan pada Tri Dharma Perguruan Tinggi. Pengabdian masyarakat ini sebagai wujud dari program kegiatan Kuliah Kerja Nyata Tematik dari rumah (KKN DR) IAIN Kediri yang dilakukan secara virtual dan memperhatikan protokol kesehatan yang berlaku. Bentuk kegiatan ini bermacam­-macam diantaranya adalah kampanye media sosial dan pengajaran. Kampanye media sosial digunakan sebagai bentuk edukasi masyarakat tentang Covid-19 sedangkan pengajaran merupakan bentuk nyata kepedulian tentang pendidikan di masa pandemi. Kegiatan penerapan pembelajaran pada materi Fikih menggunakan metode demonstrasi ini dilakukan di Kelurahan Ngronggo kepada anak-anak TPQ al-Hikmah ang bertujuan memberikan alternatif di masa pembelajaran agama di masa pandemi. Hasil dari pengabdian tersebut menunjukkan respon positif, dimana anak-anak dapat menerima pembelajaran Fikih dan mendemonstrasikan agar dapat membantu mereka untuk belajar pendidikan agama Islam dengan lebih mudah dan bermakna.
This community service aims to introduce Fiqh learning using the demonstration method as an alternative teaching during the Covid-19 pandemic. This community service is based on the Tri Dharma of Higher Education. This community service is a manifestation of the Thematic Real Work Lecture from home (KKN DR) IAIN Kediri program which is carried out virtually and takes into account the applicable health protocols. These activities take various forms, including social media campaigns and teaching. Social media campaigns are used as a form of public education about Covid-19, while teaching is a real form of concern about education during the pandemic. The activity of implementing learning on Fiqh material using the demonstration method was carried out in Ngronggo Village for TPQ al-Hikmah children with the aim of providing an alternative during religious learning during the pandemic. The results of this service show a positive response, where children can receive Fiqh learning and demonstrate so that it can help them to learn Islamic religious education more easily and meaningfully.
Efeitos da nutrição, genética e sua interação sobre o metabolismo animal
Authors: Del Vesco Ana Paula , Gasparino Eliane , Menck Soares Maria Amélia , Marques Voltolini Débora , De Souza Khatlab Angélica
Published: November 2021

Esta revisão trata de fatores que influenciam no desempenho das aves. Características produtivas importantes para o sucesso na produção de aves, como taxa de ganho de peso diário e composição do ganho de peso (proteína e gordura) são influenciadas por diversos mecanismos biológicos. A composição nutricional da dieta pode influenciar a fisiologia e a expressão de vários genes, e assim tornar os animais mais ou menos eficientes em converter alimentos em crescimento corporal. Desta forma a revisão aborda hormônios e proteínas envolvidos no crescimento e eficiência alimentar das aves, bem como alguns efeitos da interação entre a nutrição e a genética sobre o metabolismo animal.
Curtimento de rúmen e retículo de bovinos: qualidade de resistência
Authors: Do Prado Marcellie , Rodrigues de Souza Franco Maria Luiza , Coutinho Machado Andressa , Dorta de Souza Emilia , Uchimura Claudia Mari , Gasparino Eliane , Del Vesco Ana Paula
Published: November 2021

O objetivo deste experimento foi avaliar as características de resistência do rúmen e do retículo submetidos ao processo de curtimento com diferentes agentes curtentes. Quarenta rúmens e retículos foram curtidos com sais de cromo e distribuídos em quatro diferentes recurtimentos (Trat1 = sais de cromo; Trat 2 = tanino vegetal; Trat 3 = tanino sintético e Trat 4 = tanino vegetal + sintético). O rúmen apresentou maior elasticidade, diferindo significativamente do retículo. A técnica de recurtimento com tanino sintético conferiu maior elasticidade e o vegetal + sintético menor elasticidade (86,05% e 68,77%, respectivamente). Os rúmens apresentaram resistência à tração (2,14 N/mm2) e rasgamento progressivo (21,93 N/mm) significativamente maior quando comparados aos dos retículos (1,82 N/mm2 e 12,20 N/mm, respectivamente). Os rúmens e retículos recurtidos com tanino sintético (2,13 N/mm2) apresentaram maior resistência à tração entre os tratamentos, diferindo significativamente dos recurtidos com tanino vegetal (1,40 N/mm2). A utilização de tanino sintético (21,03 N/mm) conferiu maior resistência ao rasgamento progressivo, porém não diferiu significativamente do cromo (15,99 N/mm) e tanino vegetal (17,44 N/mm). Não houve diferença significativa para alongamento. Apesar de baixa resistência após o curtimento dos rúmens e retículos, estes apresentaram uma grande beleza para aplicação como detalhes em artefatos em geral.