bluuebunny/crossref_metadata_2025 huggingface dataset:
A study on Professionality for Elementary Teacher in Assessing Korean Language: Based on assessment question item development
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Im Cheon Taek
Published: July 2023

This study researched assessment tool development for Elementary Teacher in assessing Korean Language. With this tried to observe a part of professionality for elementary teacher in assessing Korean Language. I set four kind analytical focuses accomplishing standard, performance characteristic, thinking characteristic, question item suitability. And analyzed studies accomplishing question items 60 and performance assessment question items 18 of 2 grade 1 semester. Those were collected from three elementary schools. Question and direct conversation led and in addition collected analyzed a data about assessment tool development. The result with after words is same.
Teachers who made the question items for studies accomplishing assessment had a proper question item development ability in accomplishing standard and question item suitability. But the question item development ability which is sufficient an performance characteristic and thinking characteristic was insufficient. According to area characteristic and accomplishing standard characteristic the accomplishing standard reflection degree, performance characteristic reflection degree and thinking characteristic reflection degree appeared differently. This was ratiocinated. with the fact that the convenient characteristic of question item development operated.
Teachers who made the question items for performance assessment had a proper question item development ability in performance characteristic and thinking characteristic reflecting the performance characteristic of Korean Language and characteristic of performance assessment. But it appeared the set of assessment standard which is objective and consistent was insufficient from part. Also it understands a area by mistake or does not reflect a corresponding area characteristic does not reflect an accomplishing standard with the result well from part.
Competitive ability of common bean cultivars in the presence of Urochloa plantaginea
Authors: Henz Neto Otilo Daniel , Toso Janaíne Oliveira , Galon Leandro , Müller Caroline , Forte Cesar Tiago , Brunetto Leonardo , Giacomini João Paulo , Perin Gismael Francisco
Published: July 2023

Weeds are the main constraints to high bean productivity. Here, we aimed to investigate the competitive ability of black type bean cultivars BRS Campeiro and SCS Predileto in coexistence with alexandergrass, Urochloa plataginea. The experimental design employed a replacement series arrangement, and the experiments were conducted in a greenhouse using a randomized block design with four replicates. Once the appropriate plant density was determined, the experiments proceeded with the following ratios of bean to U. plataginea plants per pot: 20:00, 15:5, 10:10, 5:15, and 0:20. Fifty-five days after the emergence of the plants, physiological and morphological traits were analyzed. Diagrams were made to analyze the relative productivity (RP), total relative productivity (TRP), and the competitiveness indices. Based on RP and TRP, a similar competitive mechanism for environmental resources was observed for both bean cultivars in the presence of U. plataginea. Variables such as leaf area, dry matter, stem diameter, and plant height of the bean cultivars were negatively affected by U. plataginea, indicating a superior competitive ability for environmental resources. However, considering only the 10:10 plants per plot ratio, beans showed higher relative growth than U. plataginea, represented by relative competition indices, relative clustering coefficients, and aggressiveness. Intraspecific competition was found to be more harmful than interspecific competition for both crop and weed species.
MORF9 mediating plastid RNA editing influences Arabidopsis root growth under sugar starvation
Authors: Miao Ying , Xie Yakun , Yu Jinfa , Tian Faan , Li Xue , Chen Xinyan , Li Yanyun , Wu Binghua
Published: July 2023

RNA editing converts cytidines to uridines in the RNAs transcribed from
the chloroplast and mitochondrial genomes in flowering plants. Multiple
organellar RNA editing factor (MORF) complex is discovered to be highly
associated with C-to-U RNA editing activity of vascular plant editosome.
However, mechanism of MORF9 mediating plastid RNA editing controlling
plant development and in response to environmental cues remains limited.
In this study, we found that loss of MORF9 function impaired PSII
efficiency, NDH activity, and carbohydrate production, rapidly promoted
nuclear gene expression including sucrose transporter and sugar/energy
responsive genes, exhibiting a retard seedling development under sugar
starvation condition. When exogenous application of sugar increased
transcript and protein level of MORF9 and MORF2 in wild-type, and
enhanced the decreasing of matK-706C, accD-794C, ndhD-383C
and ndhF-290C RNA editing efficiency in morf9 mutant, and
partially recovered altered cell division of root meristem zone, and
nuclear gene expression in morf9 mutant. Using gin2, snrk1,
morf9 single and double mutants and overexpressing SnRK1 (KIN10)
or HXK1 in morf9 mutant background genetically addressed
that RNA editing efficiency of ndhD-383C and ndhF-290C
sites was declined in the gin2morf9, that of matK-706C,
accD-794C, ndhD-383C and ndhF-290C sites was significantly declined in
the snrk1morf9, while overexpressing HXK1 or SnRK1
promoted RNA editing rate of matK,accD, ndhD, and
ndhF in leaves of morf9 mutant，indicating that HXK1 might
require for MORF9 mediating ndhD-383C and ndhF-290C
editing, SnRK1 only require for MORF9 mediating ndhF-290C site
editing. It suggests that sugar as an energy/sugar signal impairs MORF9
mediating plastid RNA editing affecting plant root development.
High-resolution Multi-reflection Time-of-Flight Mass Spectrometer with Atmospheric Pressure Interface
Authors: Huang Zhengxu , Yan Shuxiong , Ren Yi , Huang Qi , Hong Yi , Chen Zhengge , Li Mei
Published: July 2023

RATIONALE: Many chemical processes operate at unsteady state
and require a rapid mass analysis of transients with high resolution. An
atmospheric pressure interface multi-reflection time-of-flight mass
spectrometer (API-MRTOF-MS) has the potential to be a powerful process
analytical tool. METHODS: The ion flight path of the
API-MRTOF-MS was extended from meters to over one kilometer, and the
mass resolution was increased to an ultra-high level. Furthermore, the
mass analysis could be done at around ten milliseconds due to the
rapidity of TOFMS. The mass analyzer reflects ions via electrostatic
mirrors and directs them along a folded flight path, significantly
increasing flight distances and theoretically with no upper limit. The
powerful API, equipped with two quadrupoles, makes the API-MRTOF-MS
suitable for complex mass spectrometry methods with alternative ion
selection schemes. RESULTS: A mass resolution of 116,050 for Cs
ions is achieved within a total time-of-flight of
only 18 ms. An ion transmission efficiency of over 50% was achieved
after 600 cycles. CONCLUSIONS: The performance of the
API-MRTOF-MS demonstrates that it is exceedingly suitable for
high-resolution process analysis, particularly for transient process
analysis, due to its fast analysis speed and high-selectivity.
Constraint on Net Long Term Climate Feedback to Emerge From Satellite Observed Internal Variability by Mid 2040s
Authors: Uribe Alejandro , Bender Frida A.-M. , Mauritsen Thorsten
Published: July 2023

Climate feedbacks are vital in shaping the extent of global warming.
While directly observing climate feedbacks is hardly feasible, it is
possible to establish a relationship between them and
top-of-the-atmosphere flux changes in response to natural fluctuations
in surface temperature. In this study, we explore this method to
potentially constrain climate feedbacks in climate models using
observations. Our findings reveal significant correlations for longwave
and shortwave feedbacks within a period of 14 years. This allows for
utilizing satellite observations and reanalysis to show that models
exhibiting moderate negative longwave and moderate positive shortwave
internal variability feedbacks demonstrate better consistency with
observations. The emergence of the relationship for the net feedback
requires a longer time, about 60 years. Continuous satellite records
need to be maintained minimum until the mid-2040s before estimates of
observed net internal variability feedback can be used to constrain net
forced climate feedback, and thereby climate sensitivity.
Observations and biogeochemical modeling reveal chlorophyll diel cycle with near-sunset maxima in the Red Sea
Authors: Wang Yixin , Mazloff Matthew R. , Verdy Ariane , Cerovecki Ivana , Naylor Patrick , Krokos George , Hoteit Ibrahim
Published: July 2023

The Red Sea is an extremely warm tropical sea that hosts diverse
ecosystems; thus, it is important to understand its ecology in the
context of global warming. Using a coupled physical–biogeochemical
model validated against in situ data, we provide the first report on the
diel cycle (i.e., diel variability) in the Red Sea chlorophyll (CHL)
concentration, revealing near-sunset CHL maxima at 17h ± 1h local time
over the entire basin. This CHL peak time is considerably later than
those reported in most other oceans, suggesting low grazing rates in
this high-irradiance tropical sea. Model-based analyses reveal that CHL
diel cycle is predominantly controlled by irradiance, whereas
longer-timescale (e.g., seasonal) CHL variability is regulated by
nutrient availability, suggesting a light-limited biological production
at diel timescale. The identified CHL diel cycle comprises a fundamental
component of the Red Sea ecology and has implications for CHL remote
sensing and in situ measurements.
“The music is highly eclectic, and it should be approached accordingly”: Voice in Jug Markovic's compositions
Authors: Radovanovic Bojana
Published: July 2023

Music for voice holds a special place in the opus of Serbian composer Jug Markovic. In all of his pieces, Markovic maintains a type of care for the vocal part that distinguishes him in the context of Serbian art music, and, at the same time, puts him on the international map of contemporary composers who work with voice in non-traditional ways. This is reflected in his intention to diversify performing techniques and vocal styles, in the detailed instructions regarding technique and scenic gesture, and in the use of technological means in vocal performance and manipulation of sound. In this paper, I investigate the expansion of vocal and bodily expression via performing techniques and new technologies, and address the issues of autonomy, agency, and responsibility of composer and vocal performer, in order to determine the characteristics and different factors of eclecticism in Markovic?s vocal music.
Bagaimana Dampak Permainan Tradisional Pada Perkembangan Motorik Siswa: Systematic Literature Review
Authors: Siswanto Siswanto , Winarno M E , Adi Sapto , Setiawan Edi
Published: July 2023

Tujuan penelitian ini adalah untuk mengetahui dampak permainan tradisional terhadap keterampilan motorik pada siswa sekolah dasar. Metode yang digunakan dalam penelitian ini yaitu literatur review menggunakan 3 database yang terdiri dari Google Scholar, Eric, dan Sage Journal, pada tahap pengumpulan artikel, peneliti menyertakan kritetia inklusi dengan jenis artikel berupa research article, artikel yang telah terindeks scopus (Q1-Q4) dan sinta (S1-S4), terbitan artikel selama 5 tahun terakhir, dan sampel penelitian berupa sekolah dasar atau usia 6-12 tahun. Hasil analisis artikel yang telah dilakukan terdapat 16 artikel membahas tentang pengaruh permainan tradisional terhadap keterampilan motorik siswa sekolah dasar. Kesimpulan pada penelitian ini yaitu permainan tradisional memberikan pengaruh yang sangat signifikan terhadap perkembangan keterampilan motorik kasar dan keterampilan motorik halus siswa sekolah dasar. Panduan permainan tradisonal dikembangkan untuk pembelajaran motorik yang disesuaikan dengan standar tingkat pencapaian perkembangan siswa. Permainan tradisional merupakan salah satu jenis permainan yang dapat memberikan manfaat untuk perkembangan pertumbuhan siswa. Permainan tradisional mempunyai dampak yang erat dengan perkembangan intelektual, sosial, serta karakter siswa.
The Neoproterozoic–Paleozoic basement in the Alpidic Supragetic/Kučaj units of eastern Serbia: a continuation of the Rheic Ocean?
Authors: Spahić Darko , Gaudenyi Tivadar , Glavaš-Trbić Bojan
Published: July 2023

This paper attempts to allocate a segment of the Paleozoic Ocean situated in what is now Southeastern Europe (SEE) into a regional geological and paleotectonic synthesis connecting the sedimentary, metamorphic and igneous records associated with the ocean’s cycle. The Supragetic basement (external section of the Carpatho-Balkan arch) represents a tectonically reworked basement vestige of the Neoproterozoic–Lower Paleozoic oceanic floor system recrystallized under regional low temperature greenschist-facies conditions. The regional geological constraints associated with this low-grade basement are integrated with information from the overlying Silurian, Devonian and Lower Carboniferous cap-rocks of the “Kučaj Unit” to demonstrate the presence of a major Paleozoic ocean crossing this segment of SEE. In connection with the Lower Paleozoic north Gondwanan Pan- African processes, the low-grade Supragetic basement (including its Devonian cover) is in a complex relationship with the occasionally anchimetamorphic Silurian, Devonian, and Lower Carboniferous deep-water record of the polymetamorphic “Kučaj Unit”. The Upper Devonian–Lower Carboniferous flysch and molasse of the “Kučaj Unit” are interposed with the Neoproterozic–Lower Paleozoic oceanic vestige or with the Supragetic basement with the corresponding Devonian Balkan-Carpathian back-arc ophiolite-bearing lithosphere and its carrier (Danubian Unit). This regional-scale synthesis demonstrates that a segment of the Rheic Ocean referred to as the Saxo-Thuringian seaway and its suture lay to the east, underneath the Permian red-bed overstepping sequence and to the west of the Danubian aggregation. Unlike many of the high-pressure rocks characterizing the segment of the Rheic suture in the Central European Variscides, the SEE zone described here has only a mild overprint.
Opportunities and Reasons for the Protection of the Steel and Mining Plant Bolesław, Małopolskie Voivodeship, Poland on the Background of Law Possibilities
Authors: Stankiewicz Barbara , Sąsiadek Zbigniew
Published: July 2023

The industrial heritage of the 1960s and 1970s includes post-mining buildings, most of them abandoned and neglected. The question is whether they should be protected? Is protection possible under the law in force? Polish law does not regulate these issues. This work shall use the Zakłady Górniczo Hutnicze Bolesław (Steel and Mining Plant) based in Bolesław, a city in Lesser Poland, as an example. Spatial arrangements of two mines, both of which belong to the ZGH Bolesław, were subject to analysis, together with their constructional aspects, as well as the present condition of the shaft towers and the head-pit buildings. The conclusions concern the possibility of utilizing the statutory and the non-statutory methods of assessing post-mining structures as a form of tools that are used to protect them and as a form of a recommendation for providing their comprehensive historical, cultural, and social valuation. Moreover, the research was also based on archival materials provided by ZGH Bolesław as well as in-situ studies.
Energy-Active Shadow Structures in Single-Family Buildings – Application Possibilities and Architectural Conditions
Authors: Uherek-Bradecka Barbara , Rozpondek Maciej , Kasprzyk Grzegorz
Published: July 2023

Existing approaches to indoor environmental quality in single-family residential buildings have been described, identifying their optimal preferred parameters for maintaining a human-healthy environment. The energy requirements for maintaining basic building systems (lighting, cooking, heating, ventilation, cooling) have been analyzed. Passive and active sources of energy production have been analyzed, prosumer buildings have been considered, and methods of obtaining maximum energy in winter periods and avoiding overheating of the building in summer periods have been discussed. Process schemes of using active shadow structures as an integral element with other systems acquiring energy from RES in single-family residential buildings have been presented. Architectural aspects of the use of energy-active shadow structures in residential buildings (single – family houses) have been presented together with alternative solutions. This paper presents process diagrams of the use of energy-active shadow integrated with other renewable energy sources used in single-family buildings, such as: BIPV, PVT and heat pumps, benefiting indoor environmental quality. Architectural considerations for the use of energy-active shadow structures in single-family homes have been presented along with alternative solutions. The purpose of this paper is to present a concept (especially effective in the summer) for an additional way to harvest electricity from energy-active shadows in single-family houses.
The Impact of Polypropylene Fibre Addition on the CBR Value
Authors: Dobrzycki Patryk
Published: July 2023

The classic test for soil or aggregate bearing capacity in road construction is the CBR test. The results of the CBR were determined for gravelly sand and sand with the addition of 1.5% cement, as well as for their mixtures with 18 mm long polypropylene fibres in the amounts of 0.1%, 0.2% and 0.3%. The effect of compaction and time of curing of samples stabilised with hydraulic binder were also determined. The natural soil without cement and fibre additions had relatively high CBR values. The additions of 0.1% and 0.2% polypropylene fibres to the dry mass of the soil resulted in an approximately 2-fold increase in the CBR value for the samples compacted using the standard method. Increasing the amount of fibres to 0.3% caused a reduction in the CBR value to that obtained without fibre addition. For samples compacted using the modified Proctor method, the observations are different. Only the sample with 0.2% fibre addition achieved a slightly higher CBR value. Moreover, the addition of 1.5% cement and the length of treatment increased the CBR values.
The Role of Selected Technological Processes in Drinking Water Treatment
Authors: Wiewiórska Iwona
Published: July 2023

The selection of appropriate technological processes for water treatment has a key impact on the qualitative safety of water intended for human consumption. The article analyzes water treatment processes used in a selected Water Treatment Plant (WTP) in terms of surface and ground water treatment. Five-year results of the research are presented on selected physico-chemical and bacteriological parameters of water quality before treatment processes, after individual stages of treatment (settling tanks, DynaSand® filters, ozonation, carbon filters, UV rays and chlorine gas disinfection). The reduction of key pollutants at individual stages of technological processes was calculated. The results of the analyzes demonstrated that the technological processes used in WTP effectively remove turbidity, color, UVA254nm, permanganatate oxygen demand, Fetotal, Mn, coliform bacteria, Enterococcus faecalis and Clostridium Perfringens from the surface and underground water. Studies have shown that infiltration in the ground effectively removes selected pollutants from water and its effectiveness is comparable to high-efficiency treatment processes.
Analytic solution of fractional order Pseudo-Hyperbolic Telegraph equation using modified double Laplace transform method
Authors: Abdulazeez Sadeq Taha , Modanli Mahmut
Published: July 2023

The Pseudo-Hyperbolic Telegraph partial differential equation (PHTPDE) based on the Caputo fractional derivative is investigated in this paper. The modified double Laplace transform method (MDLTM) is constructed for the proposed model. The MDLTM was used to obtain the analytic solution for the pseudo-hyperbolic telegraph equation of fractional order defined by the Caputo derivative. The proposed method is a highly effective analytical method for the fractional-order pseudo-hyperbolic telegraph equation. A test problem was presented as an example. Based on the results, it is clear that this method is more convenient and produces an analytic solution in fewer steps than other methods that require more steps to have an identical analytical solution. This paper claims to provide an analytic solution to the fractional order pseudohyperbolic telegraph equation order using the MDLTM. An analytical solution leads to an exact, closed-form solution that can be expressed in mathematical functions or known operations. Obtaining analytic solutions to PDEs is often challenging, especially for fractional order equations, making this achievement noteworthy.
Wavelets approach for the solution of nonlinear variable delay differential equations
Authors: Srinivasa Kumbinarasaiah , Mundewadi Ravikiran Ashok
Published: July 2023

In this study, the Laguerre wavelet-oriented numerical scheme for nonlinear first and second-order delay differential equations (DDEs) is offered. The proposed technique is dependent on the truncated series of the Laguerre wavelets approximation of an unknown function. Here, we transform the different ordered DDEs into a system of non-linear algebraic equations with the help of limit points of a sequence of collocation points. Four nonlinear illustrations are involved to prove the efficiency of the planned technique. the Obtained results are equated with the current results, indicating the proposed technique’s accuracy and efficiency.
The catastrophe of rabies encephalitis: A case series
Authors: Jha Satya , Yadav Taruna , Rohila Amit Kumar , Sharma Sanjiv Kumar , Tiwari Sarbesh
Published: July 2023

Rabies is one of humankind’s oldest and most fatal zoonotic diseases. Few cases of survival post rabies infection have been documented so far. Due to its rapid course of progression, patients succumb before acquiring magnetic resonance imaging (MRI). However, in cases where MRI is feasible, the latter is a valuable source of information that aids in antemortem confirmation of diagnosis when backed by clinical data. We present two cases of rabies encephalitis, with classic imaging features on MRI. Symmetrical involvement of the basal ganglia, mesial temporal lobes, and dorsal portion of the brainstem should raise a suspicion of rabies encephalitis in the proper clinical situation.
Fullerene functionalized halogen bonding heteroditopic hosts for ion-pair recognition
Authors: Bąk Krzysztof M. , Marqes Igor , Kuhn Heike , Christensen Kirsten , Félix Vítor , Beer Paul D.
Published: July 2023

Despite their hydrophobic surfaces with localized π-holes and rigid well-defined architectures providing a scaffold for preorganizing binding motifs, fullerenes remain unexplored as potential supramolecular host platforms for the recognition of anions. Herein, we present the first example of the rational design, synthesis, and unique recognition properties of novel fullerene-functionalized halogen bonding (XB) heteroditopic ion-pair receptors containing cation and anion binding domains spatially separated by C60. Fullerene spatial separation of the XB donors and the crown ether complexed potassium cation resulted in a rare example of an artificial receptor containing two anion binding sites with opposing preferences for hard and soft halides. Importantly, the incorporation of the C60 motif into the heteroditopic receptor structure has a significant effect on halide binding selectivity, which is further amplified upon K+ cation binding. The potassium cation complexed fullerene based receptors exhibit enhanced selectivity for the soft polarizable iodide ion which is assisted by the C60 scaffold preorganizing the potent XB-based binding domains, anion-π interactions and the exceptional polarizability of the fullerene moiety, as evidenced from computational DFT calculations. These observations serve to highlight the unique properties of fullerene surfaces for proximal charged guest binding with potential applications in construction of selective molecular sensors and modulating the properties of solar cell devices.
ON THE RATIO OF THE LEGAL CONSEQUENCES OF A FEIGNED DEAL AND VIOLATION OF THE FEIGNFULLNESS PROHIBITION IN ACCOUNTING
Authors: Зверева П.К. , Кириллов Д.А.
Published: July 2023

Объектом исследования выступает финансово-правовой запрет на регистрацию притворных объектов бухгалтерского учета, включая притворные сделки в учетных регистрах (далее – «запрет на притворность») в контексте отсутствия запрета на притворные сделки в гражданском законодательстве. Цель работы – изучение целесообразности согласования законоположений о «запрете на притворность» и о притворных сделках. Задачи исследования – проведение сравнительно-правового анализа «запрета на притворность», сравнение правовых последствий притворных сделок и «запрета на притворность», выявление причин различий отраслевых подходов. Обосновано, что «запрет на притворность» не только противоречит гражданскому законодательству, но и влечет неосновательные ограничения прав организаций. Сделан вывод о необходимости коррекции финансового законодательства.

The object of the study is a financial and legal a prohibition on the registration of feigned accounting objects including feigned deals in accounting registers (hereinafter referred to as the "feignfullness prohibition") in the context that civil law does not prohibit feigned deals. The purpose of the work is to study the expediency of coordinating the legal provisions on the "feignfullness prohibition" and on feigned deals. The objectives of the study are to conduct a comparative legal analysis of the "feignfullness prohibition", to compare the legal consequences of feigned deals and the "feignfullness prohibition", to identify the causes of differences in branch-law approaches. It is proved that the "feignfullness prohibition" not only contradicts civil law, but also entails unjustified restrictions on the rights of organizations. The conclusion is made about the need to correct the financial legislation.
The C-terminal tail of CSNAP attenuates the CSN complex
Authors: Füzesi-Levi Maria G , Ben-Nissan Gili , Listov Dina , Fridmann Sirkis Yael , Hayouka Zvi , Fleishman Sarel , Sharon Michal
Published: July 2023

Protein degradation is one of the essential mechanisms that enables reshaping of the proteome landscape in response to various stimuli. The largest E3 ubiquitin ligase family that targets proteins to degradation by catalyzing ubiquitination is the cullin–RING ligases (CRLs). Many of the proteins that are regulated by CRLs are central to tumorigenesis and tumor progression, and dysregulation of the CRL family is frequently associated with cancer. The CRL family comprises ∼300 complexes, all of which are regulated by the COP9 signalosome complex (CSN). Therefore, CSN is considered an attractive target for therapeutic intervention. Research efforts for targeted CSN inhibition have been directed towards inhibition of the complex enzymatic subunit, CSN5. Here, we have taken a fresh approach focusing on CSNAP, the smallest CSN subunit. Our results show that the C-terminal region of CSNAP is tightly packed within the CSN complex, in a groove formed by CSN3 and CSN8. We show that a 16 amino acid C-terminal peptide, derived from this CSN-interacting region, can displace the endogenous CSNAP subunit from the complex. This, in turn, leads to a CSNAP null phenotype that attenuates CSN activity and consequently CRLs function. Overall, our findings emphasize the potential of a CSNAP-based peptide for CSN inhibition as a new therapeutic avenue.
Brain IGF-I regulates LTP, spatial memory, and sexual dimorphic behavior
Authors: Herrero-Labrador Raquel , Fernández-Irigoyen Joaquín , Vecino Rebeca , González-Arias Candela , Ausín Karina , Crespo Inmaculada , Fernández Acosta Francisco J , Nieto-Estévez Vanesa , Román M José , Perea Gertrudis , Torres-Alemán Ignacio , Santamaría Enrique , Vicario Carlos
Published: July 2023

Insulin-like growth factor-I (IGF-I) exerts multiple actions, yet the role of IGF-I from different sources is poorly understood. Here, we explored the functional and behavioral consequences of the conditional deletion ofIgf-Iin the nervous system (Igf-IΔ/Δ), and demonstrated that long-term potentiation was impaired in hippocampal slices. Moreover,Igf-IΔ/Δmice showed spatial memory deficits in the Morris water maze, and the significant sex-dependent differences displayed byIgf-ICtrl/Ctrlmice disappeared inIgf-IΔ/Δmice in the open field and rota-rod tests. BrainIgf-Ideletion disorganized the granule cell layer of the dentate gyrus (DG), and it modified the relative expressions of GAD and VGLUT1, which are preferentially localized to inhibitory and excitatory presynaptic terminals. Furthermore,Igf-Ideletion altered protein modules involved in receptor trafficking, synaptic proteins, and proteins that functionally interact with estrogen and androgen metabolism. Our findings indicate that brain IGF-I is crucial for long-term potentiation, and that it is involved in the regulation of spatial memory and sexual dimorphic behaviors, possibly by maintaining the granule cell layer structure and the stability of synaptic-related protein modules.
Guerra Híbrida: o emprego da tecnologia da informação no conflito Rússia-Ucrânia (2014-2015)
Authors: Oliveira Marcos Aurélio Guedes de , Casalunga Fernando Henrique
Published: July 2023

Como a tecnologia da informação amplia a assimetria de poder entre os Estados contemporâneos? Com o objetivo de responder ao questionamento, o artigo descreve o processo de utilização do ciberespaço para consecução dos objetivos estratégicos da Federação Russa em seu entorno regional, durante o conflito desencadeado com a Ucrânia (2014-2015). A partir da análise de relatórios de empresas especializadas em segurança cibernética e instituições governamentais, aplicamos as técnicas qualitativas da dependência da trajetória e rastreamento de processos para explicitar a complexidade das operações conjuntas entre as forças especiais russas e hackers civis, bem como a sofisticação das principais ameaças e armas utilizadas nos ataques cibernéticos. Desse modo, identificamos o mecanismo responsável por conectar os níveis estratégico, tático e operacional militar ao verificarmos o processo de ação simbiótica entre os atores envolvidos no conflito. As evidências coletadas indicam como a guerra híbrida empregada pela Federação Russa incorporou a dimensão cibernética como peça chave para a desestabilização de territórios e consecução de interesses em seu entorno estratégico.
Estado, inovação e indústria de defesa: a simulação digital de combate nos EUA
Authors: Werle Berwaldt Julio , Castellano Igor
Published: July 2023

O artigo aborda as transformações no processo de desenvolvimento e aquisição de produtos de defesa e a reorganização institucional dos Estados, de forma a lidar com as alterações nas dinâmicas de inovação tecnológica e com o fortalecimento de empresas da sociedade civil. O trabalho contribui com o debate sobre capacidades estatais ao discorrer sobre a necessidade de adaptação dos papéis cumpridos pelo Estado frente a constrangimentos sistêmicos enquanto indício de sua efetividade. A hipótese de trabalho é que, na incorporação de novas tecnologias ao setor de defesa, não importa tanto o tipo ou a variação nas capacidades estatais, mas sim a adaptabilidade dessas capacidades frente às pressões sistêmicas de mercado. Especificamente, no caso estadunidense identificam-se mudanças de papéis desempenhados pelo Estado desde 1945 (interessado, indutor e organizador, respectivamente) que garantiram a sua capacidade de estimular o desenvolvimento tecnológico em prol da soberania. Avaliamos, por meio de estudo de caso amparado por process-tracing, os sistemas de simulação digitais de combate. O setor exemplifica o desenvolvimento de novas tecnologias aplicáveis à defesa nacional, ampliação do número de firmas no mercado, mudanças na lógica de aquisição de produtos de defesa e alterações na estrutura organizacional e nos papéis cumpridos pelo Estado.
Антимюллеров гормон и его роль в женская репродуктивная система
Authors: J.F. Gurbanova  , N.K. Kaziyeva  , R.M. Mammadova  , Q. Salakhova
Published: July 2023

В статье показана роль АМГ в периоде репродуктивного возраста у женщин с бесплодием в анамнезе. Полученные результаты показали, что изменение уровня АМГ у женщин с бесплодием свидетельствует о функциональном расстройстве яичников.Таким образом, низкий уровень АМГ свидетельствует о низком овариальном резерве, а высокий уровень АМГ свидетельствует о поликистозе яичников у этих женщин.
Türkçeyi yabancı dil olarak öğrenen c1 düzeyi öğrencilerinin paragraf tutarlılık düzeyleri
Authors: KIRİBİŞ Ali , CAN Remzi
Published: July 2023

Türkçenin yabancı dil olarak öğretimi bilgiden ziyade beceri temellidir. Anlamaya dayalı becerileri dinleme ve okuma becerisi; anlatmaya dayalı becerileri konuşma ve yazma becerisi oluşturur. Dil öğretim sürecinde bir paragrafın kurgulanabilmesi yazma becerisinin geliştirilmesini sağlar. Hedefe uygun cümle, paragraf, metin yazmak, yazma becerisinin yetkin bir şekilde kazanılması ile gerçekleşir. Uluslararası öğrencilerin bu süreçte en zorlandığı becerinin yazma becerisi olduğunu bilinmektedir. Paragrafın iyi kurgulanabilmesi için paragrafta ana fikrin ve yardımcı fikirlerin olması bu fikirlerin birbiri ile çelişmemesi, cümleler arasında mantık çerçevesinde bağlantıların açık ve net bir biçimde kurulması gereklidir. Bu unsurlar paragrafta tutarlılığı sağlar. Türkçeyi yabancı dil olarak öğrenen C1 düzeyi öğrencilerinin ele alınan düşünceyi bir ana fikir etrafında planlama, paragraflarında düşünceyi geliştirme tekniklerinden yararlanma ve paragraflarını sonuç bölümü ile bitirme gibi yeterliklere sahip olması gereklidir. Bu çalışmanın amacı, “Türkçeyi yabancı dil olarak öğrenen C1 düzeyi öğrencilerinin paragraflarındaki tutarlılık ne düzeydedir?” problem cümlesine cevap bularak bu öğrencilerin paragraf yazma becerisindeki düzeylerinden hareket ile çeşitli çözümler üretmektir. Araştırma betimsel durum saptaması niteliğindedir. Araştırma sürecinde nitel veri toplama tekniklerinden biri olan doküman incelemesi yoluyla ise öğrencilerin paragraf tutarlılık düzeyleri belirlenmeye çalışılmıştır. Katılımcıların paragraf tutarlılığını sağlamaya ilişkin düzeyleri “Paragraf Tutarlılığı Değerlendirme Envanteri” temel alınarak sayısal veriler ile açıklanmıştır. Bu öğrencilerin paragraflarında tutarlılığı oluşturabilme düzeyleri frekans sıralamasına göre 99 frekans ile yetersiz; 7 frekans ile orta; 41 frekans ile iyi ve 27 frekans ile pekiyi düzeyindedir.
Niveles de depresión de los estudiantes de educación superior como condicionantes de la deserción escolar
Authors: Garay Mendoza Martha Paola
Published: July 2023

Las enfermedades mentales del siglo XXI consideradas como las del primer lugar y causadas; la mayoría de las veces debido al contexto socioeconómico, invaden el futuro de los jóvenes estudiantes, sumiéndolos en momentos de delirio y desesperación, son sin duda un tema fresco para tomar como base una investigación, que nos dé como resultado un parteaguas para descifrar bien el camino que deben tomar los catedráticos de las universidades, además de estar atentos a los focos rojos, para guiar en todo momento la estadía dentro de la universidad de los estudiantes y evitar así la deserción escolar. La creatividad de escritores, actores y músicos entre otros, “ha sido asociada a sintomatologías afectivas o emocionales”. La continua exposición a estas situaciones puede generar un riesgo mayor de consumo de sustancias; en otros casos las adicciones pueden estar influenciadas por factores como presión laboral y social, que generalmente provoca ansiedad, o bien “debido a que se involucran desde jóvenes al abuso de sustancias”. Sin embargo cada vez más son la mayoría de la población la que está siendo afectada por este tipo de trastornos llamados coloquial mente como “locura” independientemente del nivel socioeconómico y cultural, afectando las vida de las personas, y que sin una debida atención terminan desgraciadamente claudicando la vidas funcional que tenían y ganando un déficit de vida integral.
Las pesadillas del simulacro: Los seres artificiales como figuras monstruosas (2ª parte)
Authors: Oliva Abarca Jesús Eduardo
Published: July 2023

En toda época, diversos seres artificiales han poblado la imaginación humana; animados por el mito, la magia y la ciencia, estas criaturas acompañan al ser humano en su perpetua pesquisa por descubrir los mecanismos secretos de la existencia. Este impulso de recrear la vida da origen a toda una fauna de seres de variada factura: autómatas, robots, androides y cíborgs se convierten en depositarios de los deseos e inquietudes de la especie humana y, como protagonistas de obras literarias, cinematográficas, series televisivas, historietas y videojuegos, representan a un mismo tiempo ensueños placenteros y terroríficas pesadillas. Este artículo se propone evidenciar la faceta monstruosa de los seres artificiales a través del análisis de cinco personajes emblemáticos de la literatura y el cine: la “criatura” de Frankenstein, la ginoide Hadaly, la robot María, el “Exterminador” T-800, y la replicante Rachel, figuras monstruosas en tanto amenazan con emular, y superar, al ser humano.
Una realidad incómoda, la infantilización de las masas
Authors: Ramírez Saldívar Rosa Isabel
Published: July 2023

¿Cuándo permitimos que la demagogia se apodere de las aulas? En la actualidad, la ignorancia ya no se propone como lo preocupante, sino la obstinación de mantenerse en dicho estado. ¿Qué ha sucedido con la humildad de la sabiduría? Durante nuestro escrito, se pretende enunciar una serie de eventos que diluciden el contexto actual en el que como sociedad nos estamos cerniendo. La idea central, es analizar dichas esferas y reflexionar sobre su contribución en los efectos tanto a nivel individual como social, para de esa manera tratar de entender más adecuadamente las causas de la sintomatología que se extiende. Se reflexionará sobre la situación actual de la educación, la infantilización eterna que evade las responsabilidades del Yo adulto, la victimización de las masas, y la censura políticamente correcta. Se pretende invitar a una reflexión sobre el tipo de sociedad en la que no solo estamos viviendo, sino también, fomentando.
Graph Neural Networks for Traffic Classification in Satellite Communication Channels: A Comparative Analysis
Authors: Do P. H. , Le T. D. , Berezkin A. , Kirichek R.
Published: July 2023

This paper presents a comprehensive comparison of graph neural networks, specifically Graph Convolutional Networks (GCN) and Graph Attention Networks (GAT), for traffic classification in satellite communication channels. The performance of these GNN-based methods is benchmarked against traditional Multi-Layer Perceptron (MLP) algorithms. The results indicate that GNNs demonstrate superior accuracy and efficiency compared to MLPs, emphasizing their potential for application in satellite communication systems. Moreover, the study investigates the impact of various factors on GNN algorithm performance, providing insights into the most effective strategies for implementing GNNs in traffic classification tasks. This research offers valuable knowledge on the benefits and prospective use cases of GNNs within satellite communication systems.
Implementasi Metode Bagdadi bagi Peningkatan Kualitas Baca Al-Qur’an di Pondok Pesantren Daarusshofwah
Authors: Arfah Nasution Nazli , Salmah Febriani Ina
Published: July 2023

ABSTRAK

 

Indonesia dikenal sebagai negara dengan penduduk Islam terbanyak di dunia. Rilis dari World Population Review (WPR) tahun 2020 menguraikan bahwa jumlah penduduk Indonesia sebanyak 273.500.000 jiwa. Dari jumlah tersebut, presentase umat Islam berjumlah 87,2 persen atau setara 229 juta jiwa. Jumlah ini tentu menggembirakan sekaligus menjadi tantangan utamanya dalam kemampuan membaca Alquran. Ketua Yayasan Indonesia Mengaji, Komjen Pol Dr (HC) Syafruddin, yang dikutip dari republika.co.id menyampaikan, sebanyak 65 persen dari jumlah penduduk Indonesia yang beragama Islam tidak bisa membaca Alquran. Data ini mengacu pada kajian dan penelitian mendalam oleh organisasi pemuda Islam dan tokoh-tokoh pemuda Islam.

Beberapa organisasi pemuda Islam dan tokoh-tokoh pemuda melakukan penelitian yang mendalam tentang kemampuan membaca Alquran di kalangan umat Muslim Indonesia. Alhasil, ditemukan, hanya 35 persen atau sekitar 80 juta penduduk Muslim di Indonesia yang bisa membaca Alquran. Sisanya, 65 persen atau sekitar 149 juta penduduk Muslim tidak bisa membaca kitab sucinya.

Berdasarkan fakta di atas, metode Bagdadi sebagai salah satu metode membaca Alquran menjadi jawaban. Metode yang lahir di era sebelum 1980-an kemudian disempurnakan oleh Pimpinan Pusat Jam’iyyatul Qurra wal Huffadz Nahdlatul Ulama (PP-JQHNU) telah diperkenalkan dan dipelajari di seluruh Indonesia. Tak jauh berbeda dengan beberapa metode lainnya semisal metode Yanbu’a, Ummi, al-Barqi, Qiraati, Utsmani, Jibril, hingga Iqra’, metode ini terfokus untuk meningkatkan kualitas baca al-Quran. Baik metode Bagdadi maupun beberapa metode membaca al-Quran yang telah disebutkan di atas bertujuan agar umat Islam bukan saja mengenal huruf namun mampu membaca huruf sesuai dengan makharijul huruf (tempat keluarnya huruf) beserta shifatul huruf (sifat-sifat huruf). Penelitian ini menggunakan pendekatan kualitatif dengan objek kajian di Pondok Pesantren Daarus Sofwah, Kabupaten Bogor yang telah mengimplementasikan metode Bagdadi untuk meningkatkan kualitas baca Alquran santri. Ditemukan bahwa metode Bagdadi mampu menjadi salah satu cara agar santri gemar mempelajari dan membaca Alquran meskipun ada beberapa yang merasa kesulitan terhadap metode ini. Peran guru sangat menentukan dalam keberhasilan metode ini agar kualitas membaca Alquran santri meningkat.
Improving the Quality of Life by Utilizing Social Media as a Media for Marketing Activity Therapy Product of Breast Cancer Survivor in Medan City
Authors: Hasnida  , Lubis Namora Lumongga , Lubis Ramona Dumasari , Novitarum Lilis
Published: July 2023

Breast cancer survivors have a desire to remain productive in helping the family's economic function. As housewives, breast cancer survivors have free time that can be used to earn income. Moreover, at this time, easy access to information through social media is one way to market their handicraft products. However, this is still not the main focus of the group. Considering that the average age has passed the age of 50, their ability to use social media is still very lacking. Whereas with survivors having positive activities, they are expected to increase their motivation and quality of life. The purpose of this community service is to improve the quality of life of survivors by preparing breast cancer survivors to be able to independently produce handicrafts and market them digitally through social media. Activities carried out using training and mentoring methods in using social media as an effective marketing medium. After providing assistance in uploading handicrafts to social media by using services to expand their reach, the interest of buyers began to increase and the sales of handicrafts began to increase.
Exploring the role of viral hepatitis in plasma cell disorders
Authors: O’Donnell Elizabeth
Published: July 2023

Not available.
Global Assessment of Predictive Biomarkers in Malian BCLC Stage C Hepatocellular Carcinoma Patients under Mono or Combination Immune Checkpoint Inhibitors Treatment: A Proposed Research Protocol
Authors: Kaly Keita , K Abdoulaye , Abdoulaye Diawara , AK Alou , Moussa Bathily , AK Dembélé , Mariam Sidibé , Aissata Coulibay , Bakarou Kamaté , TC Bougadari , Mamadou Wélé , Kassim Traoré , Djénéba Dabitao , O Samassekou , Ak Soukho , AK Traoré , Mahamadou Diakité
Published: July 2023

Background: According to the Barcelona Clinic Liver Cancer (BCLC) staging system, only the advanced stage (stage C) hepatocellular carcinoma (HCC) patient is eligible for systemic treatments. In addition to sorafenib and lenvatinib that represent the standard-of-care options in the first-line treatment, the multikinase inhibitors regorafenib and cabozantinib or ramucirumab, the anti-vascular-endothelial growth factor-2 (VEGF-R2) in the second-line setting but their poor tolerability have brought out the need for new therapeutic strategies, the immune checkpoint inhibitors (ICIs) might represent the most important novelty and the future perspective also in the field of HCC. Therefore, the need to identify predictive biomarkers to select those patients who might actually benefit from ICIs-based treatment is urgently a challenge. Our central hypothesis is that the global assessment of predictive biomarkers could help patient-specific choices for ICIs treatment by developing simplified therapeutic algorithms and novel prognostic index for efficient HCC management. The primary aim of this work will be to globally assess predictive biomarkers in Malian patients with BCLC stage C HCC undergoing treatment with ICIs in mono or in combination.
Coral reef pinnacles act as ecological magnets for the abundance, diversity and biomass of predatory fishes
Authors: Cresswell BJ , Galbraith GF , Harrison HB , McCormick MI , Jones GP
Published: July 2023

Predation is a key ecological process regulating the structure and diversity of biological communities, yet predators do not exist homogeneously in nature. Coral reefs possess diverse assemblages of predatory fishes, the distribution and abundance of which is well documented for coastal and emergent reefs. However, for remote, isolated and submerged reefs, such as those found on pinnacles and seamounts, our understanding of predatory fish communities is limited. These features are ubiquitous in the world’s oceans and frequently targeted by fishers for their presumed fish aggregation properties. Here we describe communities of predatory fishes on a series of pinnacle reefs and contrast these to regional coastal and offshore emergent reefs. Pinnacles supported 2-4× higher abundance, biomass and diversity of predatory fishes compared to emergent reefs. They also supported unique communities, with 32 out of the 63 predator species in our study found only on pinnacle reefs. For species found on all 3 reef types, all were most abundant on pinnacles and the 6 taxa driving differences in community structure were most abundant on pinnacles. Together, our results show that predatory fishes are strongly attracted to pinnacles, although the mechanisms are still unclear. Prioritising the selection of these small ecological magnets in conservation planning would be an effective approach to target the protection of regional reef fish biodiversity.