bluuebunny/crossref_metadata_2025 huggingface dataset:
Over expression of PTEN induces apoptosis and prevents cell proliferation in breast cancer cells
Authors: Wu Jinfeng , Gao Hong , Ge Wanyu , He Jie
Published: December 2020

The phosphatase and tensin homolog (PTEN) is a tumor suppressor lipid phosphatase frequently mutated or deleted in breast cancer cells. Loss of PTEN is associated with aberrant activation of P13K/AKT signaling pathways, which are responsible for uncontrolled cell cycle, migration and prolonged survival. Therefore, stability and functional PTEN is essential for prevention of cancer growth and migration. In the present study, we have determined the effect of PTEN over expression in apoptosis induction and cell proliferation in breast cancer cells. We showed that PTEN over expression significantly declined the cell proliferation rate during logarithmic growth phase. Furthermore, the PTEN over expression leads to the activation of mitochondrial based intrinsic apoptosis pathways, which is confirmed by the activation and over expression of caspases 9 and caspases 3. In addition, the number of apoptotic cells are significantly more in PTEN over expressed cells, where they showed more apoptotic bodies in AO-EtBr and Hoechst 33344 staining. Finally, PTEN over expressed cells showed decreased chemo resistance as chemotherapeutic drugs kill them efficiently. Therefore, our findings suggest that tumor suppressive effect of PTEN is crucial for cancer prevention and thus PTEN might be a potential target for anti-cancer drugs.
Investigating the Manifestations of Nostalgia in the Poems of Amiri Firuzkuhi
Authors: Mahdavi Batul , Kasiri Hedye
Published: December 2020

A wistful desire to return in thought or in fact to a former time in one's life is called nostalgia. It has been one of the issues raised in psychology and later was considered in literature. It turned to the source and theme of many literary works. Amiri Firuzkoohi is one of the poets who used nostalgia in his poems. This paper aims at studying the examples of nostalgia in Amiri's poems. The results show that the examples reflect a wistful desire to return to happy days of youth and childhood.
Some Effects of Unstructured Outdoor Plays on a Child: A Case Study from New Zealand
Authors: OKUR-BERBEROĞLU Emel
Published: December 2020

Outdoors are considered a rich learning environment by the researchers. The literature mentions different positive outputs of outdoor plays. There are not many studies related to unstructured outdoor plays. The aim of this study is to determine some effects of unstructured outdoor plays on a child in New Zealand. Qualitative approach is used within a case study. The defined themes at the end of the study are observing, exploring, cognitive development, creativity and self-confidence. It is needed more experimental studies with control groups.
The Out of Court Divorce Model and Its Legal Implications: A Juridical Study in Babelan District Bekasi
Authors: Nursaidah Nursaidah , Rohman Adi Nur , Rahayu Panti
Published: December 2020

Abstract:Divorce in Indonesia, legally positive, must be carried out before a panel of judges at trial in accordance with the mandate of Law Number 1 of 1974 concerning Marriage and the Compilation of Islamic Law. However, out-of-court divorce is still common in several areas including Babelan district Bekasi where some of the community still practice out-of-court divorce. Out-of-court divorce even though it is considered religiously valid, leaves various legal issues such as neglect of the rights of children and wives who are divorced to the legality of the divorce itself. This study aims to find models of out-of-court divorce that are conducted by the community. Besides that, the study of the consequences and legal efforts to overcome this phenomenon are very important to be analyzed. This research is classified as a normative-empirical juridical study using a statutory approach assisted by a sociological approach. The results showed that research outside the court was carried out by: (1) kinship, and (2) through amil. From a positive legal perspective, divorce outside the court does not have a strong legal position, resulting in neglect of the right to support, distribution of assets and subsequent marriage.Keywords:divorce, Religious Court, legal consequences Abstrak:Perceraian di Indonesia secara hukum positif harus dilakukan dihadapan majelis hakim di persidangan sesuai dengan amanat Undang-Undang Nomor 1 Tahun 1974 Tentang Perkawinan dan Kompilasi Hukum Islam. Namun demikian, perceraian di luar pengadilan masih banyak ditemui di beberapa daerah termasuk di kecamatan Babelan Bekasi dimana sebagian masyarakatnya masih mempraktikkan perceraian di luar pengadilan. Perceraian di luar pengadilan meskipun dianggap sah secara agama, tetapi menyisakan berbagai persoalan hukum seperti pengabaian hak anak dan istri yang diceraikan hingga legalitas perceraian itu sendiri.Penelitian ini bertujuan untuk menemukan model-model perceraian di luar pengadilan yang dilakukan masyarakat. Disamping itu, kajian tentang akibat serta upaya hukum menanggulangi fenomena tersebut menjadi sangat penting untuk dianalisis. Penelitian ini tergolong penelitian yuridis normative-empiris dengan menggunakan pendekatan perundang-undangan dibantu dengan pendekatan sosiologis. Hasil penelitian menunjukkan bahwa penelitian di luar pengadilan dilakukan dengan cara: (1) secara kekeluargaan, dan (2) melalui amil. Dalam perspektif hukum positif, perceraian di luar pengadilan tidak memiliki kedudukan hukum yang kuat sehingga berakibat kepada pengabaian terhadap hak nafkah, pembagian harta serta pernikahan selanjutnya.Kata Kunci: akibat hukum, luar pengadilan, perceraian, Pengadilan Agama
The Existence of Sharia Supervisory Board in Sharia Fintech: Legal Basis and Problematic in Indonesia
Authors: Prayitno Guno , Setyowati Ro'fah
Published: December 2020

Abstrak: Kehadiran Dewan Pengawas Syariah merupakan bagian dari industri keuangan syariah tak terkecuali pada Fintech Syariah. Penelitian ini dilakukan untuk mengetahui urgensi dan tantangan eksistensi Dewan Pengawas Syariah pada Fintech Syariah di Indonesia serta landasan hukumya.  Metode pendekatan yang digunakan dalam penelitian ini adalah yuridis normatif. Hasil penelitian menyimpulkan bahwa Dewan Pengawas Syariah merupakan salah satu bentuk utama kepatuhan syariah di setiap industri keuangan syariah termasuk di Fintech Syariah di dalamnya untuk mematuhi ketentuan syariah yang menjadikan pengawasan syariah sebagai bagian yang tidak terpisahkan dari kepatuhan syariah (sharia compliance). Kehadiran Dewan Pengawas Syariah memilki tantangan keterbatasan sumber daya manusia yang ahli dalam bidang ekonomi Islam, serta anggapan bahwa Dewan Pengawas Syariah hanya sebagai objek pelengkap yang tidak terlalu penting perannya.  Selain itu, karena Fintech Syariah belum memiliki regulasi tersendiri, maka dasar hukum Dewan Pengawas Syariah pada Fintech Syariah menggunakan norma dalam peraturan perundang-undangan yang lebih umum seperti Undang-Undang Perseroan Terbatas maupun Peraturan Otoritas Jasa Keuangan yang mengatur mengenai Tata Kelola Perusahaan Yang Baik Bagi Perusahaan Pembiayaan.Kata Kunci: fintech, syariah, dewan pengawas syariah. Abstract: The existence of the Sharia Supervisory Board is part of the Islamic financial industry, including Sharia Fintech. This research was conducted to determine the urgency and challenges of the existence of the Sharia Supervisory Board on Sharia Fintech in Indonesia and its legal basis. The approach method used in this research is normative juridical. The results of the study conclude that the Sharia Supervisory Board is one of the main forms of sharia compliance in every Islamic financial industry including in Sharia Fintech to comply with sharia provisions which make sharia supervision an integral part of sharia compliance. The presence of the Sharia Supervisory Board poses the challenge of limited human resources who are experts in the field of Islamic economics, as well as the assumption that the Sharia Supervisory Board is only a complementary object whose role is not too important. In addition, because Sharia Fintech does not yet have separate regulations, the legal basis for the Sharia Supervisory Board on Sharia Fintech uses norms in more general laws such as the Limited Liability Company Law and Financial Services Authority Regulations which govern Good Corporate Governance for Financing Companies.Keywords: fintech, sharia, sharia supervisory board.Keywords: fintech, sharia, sharia supervisory board.
Open Defecation Free in Kartiasa Village in The Era Of Regional Autonomy: Implementation and Barriers
Authors: Muchsin Tamrin , Saliro Sri Sudono
Published: December 2020

Abstrak: Tujuan penelitian ini untuk menganalisis keterlibatan Pemerintah Desa Kartiasa dalam melaksanakan salah satu program Sanitasi Total Berbasis Masyarakat (STBM), yaitu Open Defecation Free (ODF) pada era otonomi daerah saat ini. Penelitian ini berfokus pada bagaimana bentuk keterlibatan Pemerintah Desa ODF pada wilayah Kabupaten Sambas, yaitu Desa Kartiasa, serta faktor penghambat pelaksanaan program ODF. Tulisan penelitian ini bersifat empiris, dan untuk memperoleh data melakukan obesevasi dan wawancara. Hasil penelitian ditemukan bahwa Pemerintah Desa Kartiasa dalam melaksanakan program ODF berdasarkan pada Surat Edaran Bupati Sambas Nomor 440/16/Dinkes tentang Pelaksanaan Program Sanitasi Total Berbasis Masyarakat. Faktor penghambat pelaksanaan ODF oleh Pemerintah Desa Kartiasa yaitu rendahnya kesadaran masyarakat untuk hidup bersih, rendahnya pengetahuan masyarakat akan nilai kesehatan, tidak ada peraturan desa, terbatasnya sarana dan prasarana, dan tidak ada pengawasanKata Kunci: Pemerintah Desa, Open Defecation Free, Otonomi Daerah Abstract: The purpose of this study was to analyze the involvement of the village government in implementing one of the Community-Based Total Sanitation (STBM) programs, namely Open Defecation Free (ODF) in the current era of regional autonomy. This research focuses on how the form of ODF Village Government involvement in the Sambas Regency area, namely Kartiasa Village, as well as the inhibiting factors for the implementation of the ODF program. The writing of this research is empirical, and to obtain data, we conduct observations and interviews. The results showed that the Kartiasa Village Government in implementing the ODF program was based on the Sambas Regent Circular Number 440/16/Dinkes concerning the Implementation of the Community-Based Total Sanitation Program. The inhibiting factors for the implementation of ODF by the Kartiasa Village Government are low community awareness to live clean, low community knowledge of the value of health, no village regulations, limited facilities and infrastructure, and no supervisionKeywords: Village Government, Open Defecation Free, Regional Autonomy.
Multimodal Learning Analytics to Inform Learning Design: Lessons Learned from Computing Education
Authors: Mangaroska Katerina , Sharma Kshitij , Gašević Dragan , Giannakos Michalis
Published: December 2020

Programming is a complex learning activity that involves coordination of cognitive processes and affective states. These aspects are often considered individually in computing education research, demonstrating limited understanding of how and when students learn best. This issue confines researchers to contextualize evidence-driven outcomes when learning behaviour deviates from pedagogical intentions. Multimodal learning analytics (MMLA) captures data essential for measuring constructs (e.g., cognitive load, confusion) that are posited in the learning sciences as important for learning, and cannot effectively be measured solely with the use of programming process data (IDE-log data). Thus, we augmented IDE-log data with physiological data (e.g., gaze data) and participants’ facial expressions, collected during a debugging learning activity. The findings emphasize the need for learning analytics that are consequential for learning, rather than easy and convenient to collect. In that regard, our paper aims to provoke productive reflections and conversations about the potential of MMLA to expand and advance the synergy of learning analytics and learning design among the community of educators from a post-evaluation design-aware process to a permanent monitoring process of adaptation.
Direito, cultura e sociedade em tempos de fake news
Authors: Themudo Tiago Seixas , Almeida Fernanda Carvalho de
Published: December 2020

O objetivo deste artigo é analisar o fenômeno das fake news, notícias falsas produzidas e disseminadas através dos novos meios de comunicação digitais, capazes de influenciar as formas contemporâneas de percepção e ação social, produzindo tanto consequências políticas de largo alcance quanto econômicas. Investigaremos o contexto no qual surgem as fake news, destacando a relação existente entre a tecnocultura, a dinâmica social das democracias e as subjetividades. Por fim, abordaremos a maneira como algumas sociedades tem tentando responder aos prejuízos que as notícias falsas produzem, no esforço de regulamentar e qualificar as estruturas de comunicação, preservando integralmente as liberdades democráticas.
Problemas da teoria das fontes do direito à luz da ideia de direito como integridade de Ronald Dworkin
Authors: Coura Alexandre de Castro , Ommati José Emílio Medauar
Published: December 2020

O presente texto pretende evidenciar os problemas da tradicional teoria das fontes do Direito em face da noção de que Direito é um empreendimento coletivo e uma prática social interpretativa, como apresenta Ronald Dworkin em sua teoria do Direito como Integridade. Assim, pretendemos mostrar que a teoria das fontes do Direito parte do pressuposto positivista no sentido de que o Direito seria uma mera questão de fato, a partir da existência de uma regra de reconhecimento, padecendo, nesse ponto, daquilo que Dworkin denomina de aguilhão semântico. Retirando-se o aguilhão semântico, passa-se a perceber o Direito como um conceito interpretativo, incompatível com uma teoria das fontes que pretenda relevar, de antemão e de forma unívoca, o que seja o direito válido.
La forma di governo in Italia dopo il 1993: mutamenti e nuovi orientamenti
Authors: Sobrino Giorgio
Published: December 2020

O presente artigo descreve as mudanças na forma de governo na Itália, e as novas tendências que ocorreram nesse sentido, no período posterior a 1993. Este ano - em que ocorreu o referendo popular que revogou a lei eleitoral proporcional que havia regulamentado as eleições na Itália desde os primeiros anos da República - representa um “divisor de águas” na reconstrução da doutrina sobre a forma de governo. Iniciou-se um longo período de transição da forma de governo italiana para uma estrutura diferente à anterior, com uma conotação majoritária. Este artigo também destaca que, a partir de 2013/2014, iniciou-se uma nova fase da forma de governo na Itália (hoje ainda não facilmente classificável), devido à mudança no sistema político determinada pela irrupção do “MoVimento 5 Stelle” e, por outro lado, aos acórdãos do Tribunal Constitucional n ° 1/2014 e n ° 35/2017, que declararam ilegítimas as duas últimas leis eleitorais majoritárias.
Apresentação
Authors: Francischetto Gilsilene Passon Picoretti
Published: December 2020

*
Revisão Sistemática dos estudos experimentais publicados na “Perspectivas em Análise do Comportamento” de 2010 a 2018
Authors: Keiner Simone Assunção , Marinho Vitor Duncan , Malerbi Fani Eta Korn
Published: December 2020

O presente trabalho apresenta uma revisão sistemática dos artigos experimentais publicados na revista brasileira Perspectivas em Análise do Comportamento (RPAC) desde a sua fundação em 2010 até o ano de 2018. Foram consideradas elegíveis para análise todas as pesquisas experimentais. A análise das 15 pesquisas selecionadas revelou: (1) pequeno número de pesquisas experimentais; (2) humanos como principal tipo de participantes utilizado; (3) preferência por delineamentos intra-sujeitos e por registros computadorizados; (4) prevalência de pesquisas básicas; (5) predominância de pesquisas envolvendo equivalência de estímulos; (6) pouco uso da estatística inferencial; e (7) pouca atenção à generalização, integridade e acordo entre observadores em pesquisas aplicadas. Além dessa visão preliminar sobre o comportamento de pesquisa de analistas do comportamento, os dados obtidos pelo presente estudo sugerem a necessidade de uma maior ênfase experimental.
Comentarios sobre los Tribunales de Apelación y la Administración de Bienes Eclesiásticos
Authors: Dammert Bellido José
Published: December 2020

No contiene resumen
De las anotaciones preventivas de las demandas
Authors: Merino Reyna José
Published: December 2020

No contiene resumen
El Gobierno de la Familia
Authors: Passarelli Santero
Published: December 2020

No contiene resumen
Notas sobre el Proceso Penal
Authors: García Rada Domingo
Published: December 2020

No contiene resumen
La Mujer en la Legislación Española
Authors: Fernández Arce César
Published: December 2020

No contiene resumen
Docencia Jurídica y Estado de derecho
Authors: Ferrero Rebagliati Raúl
Published: December 2020

No contiene resumen
¿Porqué la Iglesia defiende el Derecho de Propiedad?
Authors: Leclercq Jacques
Published: December 2020

No contiene resumen
Consideraciones sobre la prueba en la doctrina y en nuestro régimen procesal civil
Authors: Nugent Ricardo
Published: December 2020

No contiene resumen
Las Naciones Unidas
Authors: Pareja Paz Soldán José
Published: December 2020

No contiene resumen
Deberes Sociales: La Justa Distribución de lo Superfluo
Authors: Vargas Ugarte Rubén
Published: December 2020

No contiene resumen
Apuntes de Derecho Registral
Authors: Avendaño Valdez Jorge
Published: December 2020

El artículo no presenta resumen.
La Relación Jurídico-Tributaria
Authors: Barrios de Orbegoso Raúl
Published: December 2020

La Relación Jurídico Tributaria u obligación tributaria, ya que en ambas formas es denominada, es una relación sui-géneris de naturaleza pú­blica, ya que en ella interviene el Estado como ente público ejerciendo su poder de soberanía. Es una obligación  ex-lege ya  que su origen mediato es la ley, manifestación de la voluntad del Estado. Estudiaremos dicha relación empezando por su fuente, es decir, porla ley que la origina, para luego estudiar su contenido y naturaleza, pasando por fin a analizar sus elementos.
Temas de Derecho Procesal
Authors: Perla Velaochaga Ernesto
Published: December 2020

No contiene resumen
La Teoría de las Constantes Jurídicas y la Historia del Derecho Peruano
Authors: Ugarte del Pino Vicente
Published: December 2020

No contiene resumen
La crisis social de nuestro tiempo y la doctrina social de la Iglesia
Authors: Echecopar García Luis
Published: December 2020

No contiene resumen
Gran Bretaña y Estados Unidos
Authors: Ferrero Rebagliati Raúl
Published: December 2020

No contiene resumen
Cumplimiento de las Disposiciones del Derecho Canónico
Authors: Dammert Bellido José
Published: December 2020

No contiene resumen
Inmutabilidad de la Cláusula Penal
Authors: Osterling Parodi Felipe
Published: December 2020

No contiene resumen
El Impuesto Territorial
Authors: Rodrigo Luis Carlos
Published: December 2020

No contiene resumen
Garantías constitucionales
Authors: Ferrero Rebagliati Raúl
Published: December 2020

No contiene resumen
El contrato bilateral
Authors: Castañeda Jorge Eugenio
Published: December 2020

No contiene resumen
Derecho y realidad social
Authors: Cornejo Chávez Héctor
Published: December 2020

No contiene resumen
Inseguridad en la tenencia de la tierra en áreas rurales de América Latina
Authors: Thome Joseph
Published: December 2020

No contiene resumen
Modificaciones al derecho de propiedad en la legislación de reforma agraria
Authors: Rubio Correa Marcial
Published: December 2020

No contiene resumen
El impuesto a la renta en la Comunidad Laboral
Authors: Cardenal Montesinos Sergio
Published: December 2020

No contiene resumen
La influencia de Kelsen en el Perú
Authors: Sobrevilla Alcázar David
Published: December 2020

No contiene resumen
Debate en torno a la acción popular
Authors: Álvarez Simonetti Manuel
Published: December 2020

No presenta resumen
Reforma agraria peruana. ¿Una nueva ideología jurídica?
Authors: Bustamante Belaúnde Alberto
Published: December 2020

No presenta resumen
La justicia en los orígenes de la Filosofía del Derecho
Authors: García Belaúnde Domingo
Published: December 2020

No presenta resumen
El nomen juris en relación con las causales de invalidez de negocio jurídico
Authors: León Barandiarán José
Published: December 2020

No presenta resumen
El rol político del abogado litigante
Authors: Trazegnies Granda Fernando de
Published: December 2020

No presenta resumen
La cesión de posición contractual
Authors: Puente y Lavalle Manuel De la
Published: December 2020

No presenta resumen
La legislación como fuente de Derecho en el Perú
Authors: Rubio Correa Marcial
Published: December 2020

No presenta resumen
Los males de la educación legal
Authors: Zile Zigurds
Published: December 2020

No presenta resumen
El amparo en la constitución de 1979
Authors: Borea Odría Alberto
Published: December 2020

No presenta resumen
El régimen presidencial en la constitución de 1979
Authors: Pareja Paz Soldán José
Published: December 2020

No presenta resumen
Régimen municipal
Authors: Quispe Correa Alfredo
Published: December 2020

No presenta resumen
Los poderes políticos del estado en la nueva constitución
Authors: Rubio Correa Marcial
Published: December 2020

No presenta resumen
Las personas, el personalismo y la constitución peruana de 1979
Authors: Fernández Sessarego Carlos
Published: December 2020

No presenta resumen
Los derechos humanos como ideología
Authors: García Belaunde Domingo
Published: December 2020

No presenta resumen
Algunas implicaciones de los métodos de enseñanza del derecho y de su reforma
Authors: Pérez Perdomo Rogelio
Published: December 2020

No presenta resumen
Clasificación de bienes muebles e inmuebles
Authors: Jara Flórez Humberto
Published: December 2020

No presenta resumen
La igualdad de derechos del hombre y la mujer en el Código Civil vigente y el proyecto
Authors: Marcenaro Frers Ricardo
Published: December 2020

No presenta resumen
El principio de cooperacion entre los estados y el Fondo Monetario Internacional
Authors: Lama Eggerstedt Miguel De la
Published: December 2020

A diferencia del Derecho Internacional clásico que se limitaba a señalar como su objeto fundamentalel mantenimiento de la paz y la seguridad internacionales, el Derecho Internacional contemporáneo enfatiza que el logro de dicho objeto implica el crecimiento económico. Así el Principio de Igualdad Soberana de los Estados es limitado a su acepción de igualdad jurídica, mientras se reconocela desigualdad económica y social existente, y se establecen normas en favor de la categoría especial de "países en desarrollo". Al Principio de Proscripción del uso de la fuerza o de la amenaza del uso de ésta, se añade el Principio de Cooperación que obliga a los Estados a colaborar entre sí para lograr el crecimiento económico, particularmente, de los países en desarrollo. El autor propone el estudio de la vigencia del Principio de Cooperación en la esfera monetaria internacional. Para ello estudia tres aspectos del Fondo Monetario Internacional que han sido especialmente criticados por los países en desarrollo: La distribución del poder votante: la escasa ligazón entre la creación y distribución de Derechos Especiales de Giro y el desarrollo: y la condicionalidad en la utilización de los recursos del Fondo.
Problemas jurídicos del sobreendeudamiento de los países en desarrollo. Relevancia actual de la doctrina de las deudas odiosas
Authors: Frankenberg Günter , Knieper Rolf
Published: December 2020

Este artículo pretende discutir la parte del problema del endeudamiento que está compuesta, fundamentalmente, por créditos utilizados para inversiones de dudoso valor desde el punto de vista del desarrollo, trabajando en base a las llamadas "deudas odiosas" del Derecho Internacional, y su vinculación con la teoría y práctica del desarrollo económico.El propósito del trabajo es contribuir a la solución del actual problema del endeudamiento y a su prevención para el futuro. Sus presupuestos básicos son, en primer lugar,que solamente mediante la incorporación de criterios objetivos que puedan ser inferidos del debate internacional sobre el desarrollo, es posible evitaruna situación aún más catastrófica; y, en segundo lugar, que el valor de desarrollo de los bienes exportados al Tercer Mundo, es un riesgo campartido por el proveedor y por el comprador conjuntamente.
El Perú frente a la Antártida: análisis preliminar
Authors: Ramacciotti de Cubas Beatriz
Published: December 2020

La Antártida, el vasto continente del Hemisferio Austral, ya imaginado por los griegos muchos siglos atrás, región de aventuras, exploraciones y pacífica investigación científica, es hoy motivo de preocupación universal. La adhesión del Perú al Tratado Antártico,en abril de 1981, significó el reconocimiento de nuestro país al régimen jurídico negociado y establecido en Washington en 1959 para el Continente Austral.Para vislumbrar la importancia de la acción peruana, se presenta en primer lugar, una visión general de las condiciones geográficas y de los recursos naturales antárticos. Luego, se realiza una síntesis de los antecedentes históricos ( descubrimientos y exploraciones), presentándose además las principales teorías que sirven de fundamento a los reclamos de soberanía de distintos estados sobre sectores del frío continente. Seguidamente,se hace referencia a los principios del Tratado Antártico de 1959, mediante el cual se crea un régimenjurídico especial para la Antártida, convirtiéndola en una inmensa zona de investigación científica dentro de un marco de cooperación internacional,dejando congelados los reclamos territoriales por un lapso de 30 años.Pero a esta etapa de remanso parece avecinarse un tiempo nuevo: de un lado, la posible revisión del Tratado Antártico en 1991, está despertando los intereses nacionales de los estados reclamantes de soberanía y de otros estados (TercerMundo) que en foros mundiales (ONU) han solicitado que la Antártida sea considerada "Patrimonio Común de la Humanidad", y de otro lado.la posibilidad de la explotación de los abundantes recursos antárticos está generando una creciente competencia -a nivel oficial y privado-- de nacionesy empresas, por los beneficios económicos que de dicha explotación se generarían.
Autonomía de la voluntad en el Código Civil peruano de 1984: comentario a los artículos 2095 y 2096
Authors: Delgado Menéndez María Antonieta , Delgado Menéndez María del Carmen
Published: December 2020

No presenta resumen
Las normas regionales y el ordenamiento jurídico nacional
Authors: Landa Arroyo César
Published: December 2020

No presenta resumen
La falta grave laboral
Authors: Pasco Cosmópolis Mario
Published: December 2020

No presenta resumen
El tiempo como fenómeno jurídico
Authors: Vidal Ramírez Fernando
Published: December 2020

No presenta resumen
Teoría práctica de las negociaciones bilaterales
Authors: Camilion Oscar
Published: December 2020

No contiene resumen
Sistema electoral y representación política en el Perú actual
Authors: García Belaunde Domingo
Published: December 2020

El presente texto es la ponencia presentada al simposio internadonal "Sistema electoral y representación política-países andinos", organizado por el Instituto de Cooperación Iberoamericana y la Fundación Ebert, en colaboración con el Centro de Estudios Constitucionales y la Cátedra de Teoría del Estado de la UNED, y que se llevó a cabo en Segovia. del 25 al 27 de noviembre de 1986. Por razones de tiempo, no se pudo considerar comentario alguno acerca de las elecciones municipales realizadas en noviembre de 1986.
Concepto y realidad de la ley natural
Authors: Interdonato Francisco
Published: December 2020

No contiene resumen
Reflexiones sobre la actuación de los principios del derecho del trabajo
Authors: Neves Mujica Javier
Published: December 2020

En este ensayo voy a analizar el caso de la suspensión del horario de verano decretada por el actual gobierno para 1986 -y repetida luego para 1987-, con la intención de reflexionar a partir de aquél sobre las posibles actuaciones que caben a los principios del Derecho del Trabajo ante las situaciones concretas.
Derecho, administración de justicia y cambio social
Authors: Zolezzi Ibárcena Lorenzo
Published: December 2020

No contiene resumen
Constitucionalismo en las Américas: una perspectiva bicentenaria
Authors: Baker Robert
Published: December 2020

No contiene resumen
Derecho Civíl ante la post modernidad
Authors: Trazegnies Granda Fernando de
Published: December 2020

El presente trabajo pretende explorar las relaciones entre Derecho y tiempo y, más particularmente, la influencia del tiempo sobre el Derecho.
Acerca de los decretos llamados de urgencia y de la adecuación a sus caracteres y peculiar naturaleza sin necesidad de una previa reforma constitucional
Authors: Cantuarias Salaverry Fernando , Oquendo Heraud Sergio
Published: December 2020

No contiene resumen
Ley penal y hecho punible en código penal peruano de 1991
Authors: Villavicencio Terreros Felipe
Published: December 2020

No contiene resumen
Método de resolución de casos penales
Authors: Hurtado Pozo José
Published: December 2020

No contiene resumen
Aproximación al estudio de la criminalidad y el derecho penal ambiental peruano
Authors: Foy Valencia Pierre
Published: December 2020

El presente estudio pretende esbozar algunos criterio u orientaciones para una aproximación crítica en relación con las actuales prácticas sociales que afectan o transgreden gravemente un conjunto de valores ambientales, valores pasibles de ser tutelados desde nuestro sistema de control penal. En ese sentido, se postula la necesidad de formular un modelo de análisis sistémico que integre los diferentes componentes que guardan relación con el fenómeno de la criminalidad contemporánea, en su variante ambiental.
Principales tratados en materia de propiedad industrial administrados por la OMPI
Authors: OMPI OMPI
Published: December 2020

No contiene resumen
El principio protector en el derecho procesal del trabajo
Authors: Pasco Cosmópolis Mario
Published: December 2020

No contiene resumen
Derecho de preferencia de los accionistas
Authors: Puente y Lavalle Manuel De la
Published: December 2020

No presenta resumen
The Origins of the lnstitutionalised Guilty Plea in the United States: Sorne Lessons from History
Authors: McConville Mike
Published: December 2020

No presenta resumen
El right of privacy norteamericano y el derecho a la intimidad en el Perú. Estudio comparado
Authors: Morales Godo Juan
Published: December 2020

No presenta resumen
Para un dictamen consultivo de la CIJ sobre el marco ético y jurídico conforme al cual debe ser regulada la deuda externa
Authors: Schipani Sandro
Published: December 2020

No presenta resumen
¿Existen los derechos naturales?
Authors: Hernando Nieto Eduardo
Published: December 2020

No presenta resumen
Determination of Different Priming Applications on Vicia freyniana Bronm. Seeds Viability Parametres
Authors: Yüksel O. , Kenanoğlu B.B. , Öncü R.G.
Published: December 2020

Background: Legumes are the second among all the families in terms of varieties and Vicia genus is the third genus within the Leguminosae family. The germination and emergence rates decrease due to some reasons such as non-homogeneous genetic structure of seed or effect of environmental factors on it. For this reason, some quality problems occur. Quality enhancing applications are performed for seeds to have the desired quality levels in seeds and eliminate the problems. The aim of the present study was to determine the viability of Vicia freyniana Bornm. seeds by different priming treatments. For this purpose, the effect of different chemicals in different doses and periods and at what rate the hot water treatment would affect testa dormancy were studied. Methods: This study was conducted in Uşak University Agriculture and Natural Sciences Faculty Research laboratory in 2019. An investigation was conducted to determine the effects of the priming treatments (Soaking and imbibation; 2, 4 and 6% doses of NaCl, CaCl2 and KNO3 salts and 75, 100 and 125 ppm doses of GA3) on seeds of Vicia freyniana Bornm. In the study, the germination rate (%), germination speed (day), germination index (day) and EC values (µS/cm g-1) of the V. freyniana seeds were determined. Result: The highest germination rates were obtained from 2% of CaCl2 and 75 ppm of GA3 treatments and the fastest germination was observed in KNO3 treatment. From the study, it is concluded that 2% dose of CaCl2 and 75 ppm dose of GA3 should be preferred in V. freyniana seeds and the impregnation technique should be preferred among priming methods due to its high germination performance.
Isolation, Molecular Identification and Multidrug Resistance Profiling of Bacteria Causing Clinical Mastitis in Cows
Authors: Vatalia D.J. , Bhanderi B.B. , Nimavat V.R. , Jhala M.K.
Published: December 2020

Background: Mastitis, the inflammation of parenchyma of mammary gland is frequently considered to be costliest and complex disease prevalent in India. Mastitis is caused by pathogens like Staphylococcus spp., Streptococcus spp., Mycoplasma bovis, E. coli, Klebsiella spp., Citrobacter spp., Enterobacter spp. and Entercoccus. The treatment of mastitis in animals is carried out using antibiotics. Treatment failure in mastitis is due to increased antibiotic resistance of mastitis pathogens and also due to indiscriminate use of antibiotics without testing in vitro antibiotic sensitivity test against causal organisms. In comparison to cultural method, PCR assays takes less time for detection of bacteria from the mastitis milk samples. Present research work was carried out regarding isolation, identification and multiple drug resistance profile of clinical bovine mastitis associated pathogens using conventional as well as molecular approach. Methods: In the present study, 73 mastitis milk samples were collected from Anand and Panchmahal district of Gujarat. The milk samples were subjected for cultural isolation and DNA extraction for identification of bacteria by cultural and PCR method. Antimicrobial sensitivity pattern of the isolates were carried by disc diffusion method and isolates were categorized in multiple drug resistant. Result: In the present study, Out of 73 mastitis milk samples collected from cows 48 (65.75%) cows were positive for bacterial isolation and S. aureus was the most predominant bacterial species. PCR from the mastitis milk additionally detected bacteria in culturally negative milk samples. Most sensitive drug was gentamicin and most of the isolates (90.19%) showed the multiple drug resistance for the two to nine drugs with 0.1 to 0.6 multiple antibiotic resistance index.
Teleradiology its Application, Transmission, Legal Issues and Market in Veterinary Medicine: A Review
Authors: . Akash , Hoque M. , . Amarpal
Published: December 2020

Teleradiology is the practice of transmitting the different radiological reports generated via X-rays, CT-scan and MRI from one part of the world to the another or one location to the other to get the consultation and interpretation from the different expert radiologists. In veterinary, it was first commercially available in the early 90s. Previously it was poorly developed due to the limited internet speed and lack of essential software but currently, the practice of teleradiology in veterinary medicine has become universal due to proper broadband connection, availability of image compression, PACS and DICOM software. This review aims to summarize the goals, applications, transmission, method of image acquisition and digitalization, types of teleradiology, its legal issues and market in veterinary medicine.
Efficiency of Different Diluents and Dilution Rates on the Fertilization Potential of Chicken Spermatozoa
Authors: Pearlin V. Beulah , Mohan J. , Tyagi J.S. , Gopi M. , Kolluri G. , Prabakar G. , Shanmathy M.
Published: December 2020

Background: Artificial Insemination (AI) has been well established to obtain better fertility than natural mating. Semen extension and preservation play a major role in AI technique. The concentrated nature of chicken semen entails dilution of semen for easy handling and storage. With the availability of a wide range of extenders, exploring various extenders and dilution rates supplement the reproductive efficiency achieved through modern AI techniques. Methods: Pooled semen samples obtained from twenty White Leghorn breeder males were split equally into three portions, each for CARI poultry semen diluent, EK extender and Tselutin extender. At 1:2 dilution rate, the samples were subjected to sperm motility analysis from 0 to 96 h and AI was targeted at 0 and 24 h of semen collection. Fertility was assessed by candling of eggs collected from 2 to 8 days post insemination at 9th day of incubation. Further investigation of different dilution rates (1:2, 1:4, 1:6, 1:8, 1:10, 1:12, 1:14, 1:16, 1:18, 1:20) on fertility of fresh semen was done using the superior diluent. Result: Upon analysis, sperm motility showed no significant difference among the diluents at 0 h storage while CARI poultry semen diluent showed superior motility (%) at the subsequent storage periods, followed by EK and Tselutin extender. Higher fertility (p less than 0.05) was expressed in the diluents of CARI and EK at 0 h storage, whereas CARI poultry semen diluent showed superior fertility pattern (p less than 0.05) followed by EK and least by Tselutin extender at 24 h semen storage. Further investigation of different dilution rates using CARI diluent, exhibited fertility (p less than 0.05) of 90% and higher at 1:2 and 1:4 dilutions, followed by 1:6 and 1:8 at 2 to 6 days of fertile period.
Development of Isothermal LAMP Assay for Detection of Intimin Gene (eae) in E. coli Associated with Piglet Diarrhea
Authors: Kumar Sanjeev , Gali Jagan Mohanarao , Dutta T.K. , Roychoudhury P. , Subudhi P.K.
Published: December 2020

Background: Diarroeagenic Escherichia coli (DEC) including enteropathogenic E. coli (EPEC) and enterohaemorrhagic E. coli (EHEC) is associated with acute diarrhoea in children and young animals. The virulence is associated with attaching and effacing lesions encoded by eaeA gene is considered as marker for EPEC and EHEC. Laboratory diagnosis of such infections is carried out by traditional bacteriological techniques and by conventional PCR assays. Those techniques often provide false negative result and at the same time are costly as well as difficult to perform in the field level. The loop-mediated isothermal amplification (LAMP) is a new generation DNA amplification assay is developed for detection of eaeA gene in E. coli isolated from diarrhoeic piglets.Methods: Samples were collected from diarrhoeic piglets for isolation and identification of E. coli. eaeA gene was detected by conventional PCR using specific primers in all the isolates. LAMP assay was standardized for detection of eaeA gene. Analytical sensitivity of LAMP was evaluated using 10 fold serially diluted E. coli genomic DNA. The specificity of the LAMP assay was determined by evaluating the cross reactivity with 19 other enteric and non-enteric bacterial species. Standardized LAMP was applied for detection of eaeA gene in the field isolates.Result: A total of 37 (24.67%) isolates were recorded as positive for eaeA gene by conventional PCR, while 49 (32.67%) isolates were recorded as positive for eaeA gene by LAMP assay. The LAMP assay was 10 times more sensitive than conventional PCR. LAMP assay was found to be more sensitive, specific, cost effective, user friendly and reliable technique over conventional PCR, which can be applied for screening of the clinical isolates for confirmation of EPEC and/or EHEC.
The effectiveness of the Montessori training programme for mothers
Authors: Yıldız Fatma Ülkü , Cagdas Aysel , Kayili Gokhan
Published: December 2020

It was the aim of this study to follow-up for 2 years the mathematics and daily living skills of children whose mothers participated in the Montessori training programme for mothers (MTPM) and to determine whether the children still maintained these skills 2 years after the intervention. In 2016–2017, the MTPM was administered to the mothers of 4–5-year-old children who received Montessori education at preschool. The first follow-up was carried out 6 months after the training programme was completed; the second follow-up took place 6 months after the first follow-up and the third one was carried out12 months after the second follow-up. Eleven children included in the study group in the 2016–2017 school year were all reached. ‘Basic School Skills Inventory 3 – Mathematics and Daily Living Skills subtests – Age 4–8 years’ were used for data collection. The data were provided by the teachers. Statistical analysis of the data was carried out using Wilcoxon’s signed-rank test and Statistical Package for the Social Sciences 20.0 data analysis package programme. The results showed that the MTPM maintained its effect on mathematics and daily living skills of the experimental group children 24 months after the implementation of the programme.

 

Keywords: Montessori training programme for mothers, mathematics, daily living skills.
relações entre divisão do trabalho, classe social e educação na antiguidade e suas repercussões na atualidade
Authors: Roggenkamp Carla Irene
Published: December 2020

As relações entre a divisão do trabalho e as classes sociais perpassam a história da humanidade. Considera-se que tais relações trazem profundas implicações para a educação. Assim sendo, este artigo tem por objetivo refletir sobre o caráter histórico das relações de dominação e poder vinculadas ao mundo do trabalho, que determinam o antagonismo social entre senhores e trabalhadores (que constituem as duas classes sociais fundamentais), e, consequentemente, as ideias e a educação em cada período do desenvolvimento social. A partir das considerações de Adorno e Horkheimer (1985) sobre o mito de Ulisses em seu encontro com as sereias, registrado na obra Odisseia, de Homero, se estabelece um debate sobre a separação, ora rígida, ora tênue, entre o trabalho produtivo/manual e intelectual/espiritual, na antiguidade, condições estas que repercutem até a atualidade.
Cyber-physical manufacturing systems: An architecture for sensor integration, production line simulation and cloud services
Authors: Prist Mariorosario , Monteriù Andrea , Pallotta Emanuele , Cicconi Paolo , Freddi Alessandro , Giuggioloni Federico , Caizer Eduard , Verdini Carlo , Longhi Sauro
Published: December 2020

The pillars of Industry 4.0 require the integration of a modern smart factory, data storage in the Cloud, access to the Cloud for data analytics, and information sharing at the software level for simulation and hardware-in-the-loop (HIL) capabilities. The resulting cyber-physical system (CPS) is often termed the cyber-physical manufacturing system, and it has become crucial to cope with this increased system complexity and to attain the desired performances. However, since a great number of old production systems are based on monolithic architectures with limited external communication ports and reduced local computational capabilities, it is difficult to ensure such production lines are compliant with the Industry 4.0 pillars. A wireless sensor network is one solution for the smart connection of a production line to a CPS elaborating data through cloud computing. The scope of this research work lies in developing a modular software architecture based on the open service gateway initiative framework, which is able to seamlessly integrate both hardware and software wireless sensors, send data into the Cloud for further data analysis and enable both HIL and cloud computing capabilities. The CPS architecture was initially tested using HIL tools before it was deployed within a real manufacturing line for data collection and analysis over a period of two months.
Geometrical and thermal influences on a bacterial cellulose based sensing element for acceleration measurements
Authors: Trigona Carlo , Di Pasquale Giovanna , Graziani Salvatore , Licciulli Antonino , Nisi Rossella , Pollicino Antonino
Published: December 2020

The need for a sustainable economy necessitates new environmentally friendly production technologies as well as devices that can be easily recycled, disposed of, and, finally, degraded, without any release of pollutants to the environment. In this context, bacterial cellulose (BC) has recently been investigated as an intriguing solution for the creation of green motion sensors. BC has excellent mechanical properties, and it is fully biodegradable and greener than the more common plant-derived cellulose. In this paper, we investigate the influence of geometry and environmental temperature on BC based sensing elements. More specifically, the influence of these quantities on a previously investigated BC-based accelerometer are reported. An experimental campaign and the characterization of the proposed green device for several geometries (from 7 to 22 mm of length) and various temperatures (from 5 °C to 55 °C) is addressed, obtaining very intriguing results.
In-Band Pumped Continuous-Wave Lasers Based on Ho:KY(WO4)2 Crystal and Ho:KGdYbY(WO4)2 Epitaxial Layer
Authors: Dernovich O. P. , Gusakovа N. V. , Kisel V. E. , Kravtsov A. V. , Guretsky S. A. , Pavlyuk A. A. , Kuleshov N. V.
Published: December 2020

2 μm lasers are in demand for a number of practical applications, such as environmental monitoring, remote sensing, medicine, material processing, and are also used as a pump sources for optical parametric generators. Crystals of double potassium tungstates doped with ions of rare-earth elements were shown to be promising materials both for  the  creation  of  classical  solid-state  lasers  and  waveguide  lasers. The aim of this work was to develop a tunable pump laser in the spectral region of 1.9 µm based on double tungstate crystals doped with thulium ions and to study the lasing characteristics of a Ho:KY(WO4)2 crystal and a Ho:KGdYbY(WO4)2 single-crystal epitaxial layer under in-band pumping.

With a Ho(1at.%):KY(WO4)2  crystal, continuous wave low-threshold lasing with an output power of 85 mW with a slope efficiency of 54 % at 2074 nm was achieved. For the first time to our knowledge, continuous wave laser  generation  in  a  waveguide  configuration  is  realized  in  a  single-crystal  layer of potassium tungstate doped with holmium ions grown by liquid-phase epitaxy. The maximum output power at a wavelength of 2055 nm was 16.5 mW.