bluuebunny/crossref_metadata_2025 huggingface dataset:
Graphene Nanoparticles: Technological Concepts and Future Applications
Authors: Zahera Manaal , Khan Aquib , Mishra Katyayani , Fatima Faria
Published: August 2024

Graphene, one of the most recent materials, has unique physical and
chemical properties. The low weight and honeycomb structure of graphene gives it
extraordinary unique properties. According to a recent study, experts from many
different disciplines, such as biological science, energy, and the environment, are
interested in graphene-based composites. These nanoparticles also show certain
biologically undesirable effects that need to be clarified. As a result, it became
important to analyse graphene's characteristics and potential uses. In this chapter,
recent advancements in the synthesis process for composites consisting of
nanoparticles and graphene, examine their properties and discuss their advantages for a
variety of applications. Additionally, the important properties of the unit cell's edges,
bond formation, bond electronic structure, and stacking sequence were emphasized.
Investigations are also conducted into how these illnesses affect the thermal, electrical,
mechanical, and chemical characteristics of graphene. Following a brief explanation of
the fundamental composition, production methods, and their properties are discussed.
Finally, present challenges in surface modification are explored, along with prospective
directions for future study. Thus this paper detailing the excellent techniques and some
cutting-edge graphene applications is necessary.
Synthesis, Preparation, and Properties of 2DGraphene for Electrochemical Energy Storage and Conversion
Authors: Shakoor Abdul , Siddiqui Rabia , Rani Malika , Arif Khizra , Dashi Marvi , Junaid Muhammad Faiz , Yousaf Jamal , Atif Muhammad , Awais Muhammad , Ajat Khel Behram Khan , Waseem Muhammad
Published: August 2024

Stimulating properties of two 2D-Graphene, like its huge surface area,
exceptional electrical conductivity, extreme thinness, amazing electron kinesis, and
state-of-the-art mechanical regulation, have added an enormous investigative concern.
This background exhibits significant dynamism and find widespread application in
various energy storage devices like Li-sulfur batteries, Li-ion batteries, Li-oxygen
batteries, sodium Ion batteries and also as a hybrid cathode/anode material for
supercapacitors. Scaled-up, stable production and correspondence of carbon-based
nano-materials are essential conditions for the preparation of graphene-based EESDs.
This chapter diagnostically explains the synthesis methods of graphene and the
properties of graphene-nanomaterials with various dimensions in adaptable EESDs.
The main tasks and scenarios in this field are also discussed.
Effect of Graphene on the Microstructure and Mechanical Properties of Metal Matrix Composites
Authors: Singh Kamaljit , Khanna Virat , Chaudhary Vishal
Published: August 2024

Metal Matrix Composites (MMCs), an advanced class of materials with
exceptional mechanical properties and tailored functionality have emerged as a
promising option for a wide range of applications. Graphene, a two-dimensional carbon
allotrope with remarkable properties, has the potential to further enhance the structural
integrity and mechanical performance of MMCs when integrated into them. Therefore,
this article reviews the results obtained from a thorough examination of the
microstructure and mechanical properties of metal-based composites, focusing on the
impact of graphene reinforcement. The microstructure and mechanical characteristics
of graphene-based MMCs are highly influenced by the amount of graphene present, the
process used, and the presence of defects. In general, graphene addition has shown
improvement in the mechanical strength, and hardness of MMCs due to refinement in
grain size. MMC characterization techniques such as scanning electron microscopy,
transmission electron microscopy, Raman spectrum and X-ray diffraction have been
discussed to understand the graphene’s dispersion, interfacial bonding with metal, and
crystallographic changes in MMC. Based on the outcomes, it can be concluded that
graphene-based MMCs have the potential to revolutionize a wide range of industries,
from aerospace and automotive to electronics and energy storage.
Introduction
Authors: Santhanam Ramasamy , Ramesh Santhanam , Balasundari Subbiah , David Sheba R.
Published: August 2024

This chapter deals with the approved drugs sourced from marine biota, the
pathophysiology of cancer, the anticancer potential of marine organisms, the most
promising marine biota-derived anticancer compounds for the different types of human
and cancer, biogeography of marine invertebrate species yielding anti cancer compounds, major constraints in the development of anticancer drugs and the remedial
measures.
Marine Bio-Chemical Diversity: Promising Anticancer Groups
Authors: Santhanam Ramasamy , Ramesh Santhanam , Balasundari Subbiah , David Sheba R.
Published: August 2024

This chapter deals with marine biodiversity and its constituents possessing
anticancer activity. The different potential groups of marine plants such as microalgae
(e.g. cyanobacteria), macroalgae (seaweeds), seagrasses, and mangroves; marine
invertebrates viz. sponges, cnidarians, bryozoans, molluscs, and echinoderms; and
tunicates among chordates producing anticancer compounds have been identified. The
chemical diversity of anticancer compounds representing different chemical classes viz.
alkaloids, terpenes, peptides, polyketides, polyphenols, glycosides etc. is also dealt
with.
Marine Biota-based Anticancer Drug Candidates in Pipeline
Authors: Santhanam Ramasamy , Ramesh Santhanam , Balasundari Subbiah , David Sheba R.
Published: August 2024

This chapter deals with the approved and marketed anticancer drugs derived
from marine sponges, mollusks/cyanobacteria, and tunicates; marine biota-derived
anticancer compounds in clinical trials i.e in III, II, and I phases; and bioactive new
chemical entities (NCEs) with anticancer function from marine biota. Limiting factors
in the development and approval of drugs from marine biota and significant challenges
in the development and approval of marine drugs are also given.
Smart Kinematics For Modern Engineering Students
Authors: Gutman Yevsey
Published: August 2024

Smart Kinematics for Modern Engineering Students is an essential reference on basic kinematics. The book provides detailed knowledge on coordinate transformations for matrix calculations, followed by information about different configurations in component pairs and joints. Readers will learn about the basic mechanical engineering methods used to design components for systems with moving parts along with various practical applications of these concepts.

Key Features

Provides-In-depth knowledge of 3D vector calculations in kinematics

Includes descriptions and depictions of major joints commonly used in engineering designs and applications

Discusses common methods of optimization for solving multivariable systems of highly nonlinear equations using displacement models

Presents practical examples of analysis applied to commonly used mechanical system

6 DOF robotic arm and moving platform

A generic Light Manufacturing Tool (LMT)

Phantom DOF devices

Temporomandibular joint (TMJ) as a biomechanical joint

Include scientific references

The material in this book will be helpful to undergraduate and graduate engineers who are required to understand knowledge about modern methods in mechanical engineering, including prerequisite courses in advanced linear algebra, kinematics and complex systems.
A Narrative Review to Identify Promising Approaches for Digital Health Interventions to Support Emotion Regulation for Adolescents With Attention-Deficit/Hyperactivity Disorder
Authors: Murray Aja Louise , Thye Melissa , Obsuth Ingrid , Cai Shufang , Lui Michael , Orr Corina , Saravanan Anusha
Published: August 2024

Emotion regulation difficulties affect many adolescents with attention-deficit/hyperactivity disorder (ADHD), and previous research has highlighted a need for accessible interventions to support them in this domain, especially in real-life contexts. Digital health interventions (DHIs) can be embedded in adolescents’ daily lives and thus offer considerable promise for meeting this need. However, there is a lack of information to guide the development of suitable emotion regulation DHIs for this population. The goal of this study is, therefore, to identify recommendations to guide the development of emotion regulation DHIs for adolescents with ADHD. This narrative review synthesizes diverse relevant evidence to inform their development, including promising therapeutic approaches and components and relevant design and development considerations. We find that there is very little direct evidence of “what works” for emotion regulation DHIs and emotion regulation interventions more generally for adolescents with ADHD; however, we identify promising therapeutic approaches for new DHIs. We also recommend following a co-design or coproduction approach with adolescents with ADHD, including exploring elements designed to motivate and engage young people to support sustained adherence. We conclude that DHIs are a promising approach for emotion regulation interventions for adolescents with ADHD, could draw on a range of existing therapeutic approaches, and should be co-designed with users themselves.
Handwriting as an objective tool to support the identification of people with Alzheimer’s disease: suitability of an assessment protocol (Preprint)
Authors: Matias Ana Rita , Borbinha Cláudia , Silva Ana Rita , Gonçalves-Montera Marta , Melo Filipe , Fernandes Orlando
Published: August 2024

BACKGROUND

Alzheimer’s disease (AD) is the most common of dementia, and has associated cognitive and motor disorders, with consequences on daily activities, including handwriting.
Handwriting has been used to study fine motor control or executive functioning in healthy and unhealthy populations. Changes in this skill are present at different stages of the clinical course of Alzheimer’s Disease. Sensorimotor deterioration is observed in handwriting tasks (motion kinematics, such as movement time, speed, and profiles) and brain activity rhythms.

OBJECTIVE

We aim to study the suitability of a handwriting assessment protocol to differentiate handwriting characteristics and the associated brain activity in older people with AD and cognitively healthy.

METHODS

Subjects from three organizations (one hospital and two Residential Centers for the Elderly) were recruited. Participants were either cognitively healthy or had clinical diagnoses of minor cognitive impairment or dementia, suggestive of AD. When a direct assessment by a neurologist was not feasible, as in the two nursing homes, participants undertook a comprehensive neuropsychological evaluation that supported the existing diagnoses by clinicians in charge. All participants performed a handwriting assessment with the following instruments: Beery Buktenica Visual-Motor Integration Development Test – 6 and Adult Writing Assessment Battery (HAB). The handwriting tasks were carried out on a Wacom digitizing platform, and the data extraction was done through the MovAlyzeR software. Participants wore an EPOC X helmet during handwriting tasks to assess brain activity.

RESULTS

The study received funding in May 2023. Data collection was initiated in January 2024. As of April 2024, 21 participants had been enrolled (female: n=17; male, n=3; cognitively healthy: n=9, dementia: n=11). Data collection finished on July 2024. Data analysis and dissemination of findings will be submitted at the beginning of 2025.

CONCLUSIONS

The findings from this research can contribute to a more in-depth knowledge of this subject and potentially support early identification and treatment.

CLINICALTRIAL

ClinicalTrials.gov Protocol Identifier:
NCT06483438
Optimizing Data Transmission in Wireless Sensor Networks Using Beetle Antennae Search Algorithm
Authors: Kumar Ravindra
Published: August 2024

Abstract: Wireless Sensor Networks (WSNs) have become an integral part of modern communication systems, enabling efficient data gathering and transmission in various applications. However, optimizing the routes for data transmission remains a significant challenge due to the energy constraints of sensor nodes. This paper presents an innovative approach to route optimization in WSNs using the Beetle Antennae Search (BAS) algorithm. The proposed method aims to minimize energy consumption and enhance network lifetime by leveraging the foraging behavior of beetles. Simulation results demonstrate the effectiveness of the BAS algorithm in optimizing routes, leading to improved performance compared to traditional methods
“Resistance and Empowerment: The Representation of Women in Arundhati Roy’s ‘The God of Small Things’ and ‘The Ministry of Utmost Happiness”
Authors: Kumar Brajesh
Published: August 2024

Abstract: This study explores the themes of resistance and empowerment in the portrayal of women in Arundhati Roy’s novels, ‘The God of Small Things’ and ‘The Ministry of Utmost Happiness’. Roy’s narratives present women who challenge societal norms and resist oppression in multifaceted ways. In ‘The God of Small Things’, characters like Ammu and Rahel navigate the patriarchal confines of Kerala society, embodying defiance against rigid cultural expectations. Through their personal struggles and transgressions, Roy highlights the complexities of female agency in a conservative setting. ‘The Ministry of Utmost Happiness’ expands this exploration into a broader socio-political context, featuring characters such as Anjum, a transgender woman, and Tilottama, who navigate their identities amidst India’s tumultuous political landscape. This novel showcases a diverse spectrum of womanhood, intersecting with themes of caste, religion, and gender identity. By focusing on the resilience and empowerment of her female characters, Roy critiques social injustices and illuminates pathways toward autonomy and selfexpression. This analysis aims to underscore the transformative power of Roy’s writing in challenging traditional narratives and advocating for a more inclusive understanding of gender and identity.
Evaluasi Parameter Genetik 42 Klon Teh (Camellia sinensis var. Sinensis)
Authors: Rafidah Ana Farah
Published: August 2024

Teh merupakan komoditas perkebunan yang berperan penting dalam kegiatan perekonomian Indonesia. Perlu upaya peningkatan produktivitas dari perkebunan teh supaya dapat bersaing yaitu melalui pemuliaan tanaman. Perakitan varietas unggul baru dengan dasar ilmu pemuliaan  memerlukan nilai parameter genetik dan keragaman dari setiap klonnya. Tujuan penelitian ini adalah melakukan evaluasi parameter genetik pada 42 klon tanaman teh varietas sinensis koleksi Pusat Penelitian Teh dan Kina. Penelitian dilakukan dengan Rancangan Acak Kelompok (RAK) dengan tiga ulangan, dimana dalam setiap ulangan terdiri dari tiga sampel tanaman untuk masing-masing klon. Karakter morfologi yang diamati berupa tinggi bidang petik, diameter batang, jumlah cabang, dan luas frame. Data dianalisis menggunakan  ANOVA atau sidik ragam pada taraf α 1% dan α 5% menggunakan  perangkat lunak PKBT STAT 3.1 yang dilanjutkan dengan analisis parameter genetik. Hasil dari penelitian ini adalah karakter yang diamati memiliki nilai variabilitas genetik, variabilitas fenotip, heritabilitas, koefisien keragaman genetik (KKG), dan koefisien keragaman fenotip (KKF) yang beragam. Karakter tinggi bidang petik, diameter batang, dan jumlah cabang memiliki variabilitas genetik dan fenotip luas. Karakter yang memiliki kemungkinan paling besar untuk dijadikan bahan seleksi yaitu jumlah cabang karena memiliki nilai parameter genetik yang luas dan tinggi karena sifat dari jumlah cabang akan mudah diturunkan ke generasi berikutnya.
Pengaruh Ekstrak Daun Kipahit dan Bandotan terhadap Empoasca flavescens pada Tanaman Teh (Camellia sinensis (L.) Kuntze)
Authors: Fauziah Fani , Eulis Eva  , Lilis Irmawatie
Published: August 2024

Empoasca flavescens merupakan salah satu hama utama teh yang dapat menyebabkan kerusakan hingga lebih dari 50%. Penggunaan pestisida nabati ekstrak daun kipahit dan bandotan merupakan salah satu alternatif pengendalian yang ramah lingkungan untuk E. flavescens. Penelitian ini bertujuan untuk mengetahui konsentrasi ekstrak daun kipahit dan bandotan mana yang paling baik dalam menekan intensitas serangan E. flavescens pada tanaman teh. Metode penelitian menggunakan Rancangan Acak Kelompok yang terdiri dari tujuh perlakuan dan empat ulangan dengan rincian; P1: Ekstrak daun kipahit 100 ml/l, P2: Ekstrak daun bandotan 100 ml/l, P3: Kombinasi ekstrak daun kipahit 50 ml/l dan bandotan 50 ml/l, P4: Kombinasi ekstrak daun kipahit 100 ml/l dan bandotan 100 ml/l, P5: Kombinasi ekstrak daun kipahit 150 ml/l dan bandotan 150 ml/l, P6: Buprofezin 0,75 ml/l (perlakuan pembanding), P7: kontrol (air). Hasil penelitian menunjukkan bahwa kombinasi ekstrak kipahit 150 ml/l dan bandotan 150 ml/l merupakan perlakuan paling baik dalam menekan populasi E. flavescens hingga 3,33 ekor/perdu dan sebanding dengan buprofezin 0,75 ml/l.
Spatial Distributio n of Economic Facilities in Tondo Urban Village, Palu City
Authors: Ikbal  , Alim Saputra Iwan
Published: August 2024

This research was conducted in Tondo Village,  Palu City with the aim of knowing the spatial distribution (distribution and distribution patterns ) of economic    facilities    in    Tondo   Village,    Palu    City,    knowing    the characteris tics  of  economic  facilities   (Shops  and  Warungs ) in  Tondo Village,  Palu City. This research is a descriptive survey method research with samples  taken using Saturated  samples (taken all)  for distribution and spatial patterns to determine the characteristics of respondents using simple random sampling,  namely   15%   of   the   population   of   38 respondents Stores  and  23  responses and  Warungs  from  the  entire population  of  253  Stores  and  152  Warungs  in  Tondo  village,  data collected through observation,  interviews ,  and  document   recording methods whose results were  analyzed  using Nearest neighbor analysis , the  results showed that the spatial distribution  pattern of  Stores  and Warungs   in Tondo Village showed a clustering    pattern. The characteristics of economic facilities  (shops and stalls ) in Tondo Village , Palu city are owned by traders with an average age of 30 to 40 years with a high school education level, the income earned from the shop business is Rp.6,293,478, per month and the average shop business income is Rp.9,131,579,   per month,  the reason for  choosing a  business location  is because they see an opportunity that the enthusiasm of buyers in this location is more promising for profit, the length of time they have been in the shop and shop business is above five years on average
Land Use Change on Potential Landslide Vulnerability in Palolo Sub-district, Sigi Regency
Authors: T Novitasaril , Budianta Aziz , Alim Saputra Iwan
Published: August 2024

the population. This s tudy aims to determine how large the extent of land-us e change that occurred in the Dis trict  of Palolo  within 13  years (2003-2016),   as well  as determine  the  potential  for lands lides  in  the Dis trict  of  Palolo  due  to  land -us e changes that  occur.  The  res earch location is in the Dis trict of Palolo, Sigi Regency. Res earch data included: LANDSAT   8  imagery,   RBI  Palolo  map,  DEM   s lope  data,  rainfall, geological type, s oil type, and population dens ity. The method of data collection is done by indirect obs ervation and calculation by Geographic Information  Sys tem (GIS)  analys is , as well as us ing the Qua ntum GIS (QGIS)   application   and  documentation  s tudy. The  method  of  data analys is is  done  us ing  image  interpretation  analys is , s caling,  coding, overlay  techniques , and des criptive analys is . The res ults  of the s tudy s how that  land-us e changes  that  occurred  in  2003  to  2016  covered
47,366.81   hectares  of the total area  of Palolo  Subdis trict, which  was
64,710.21  Ha or 73.2%.  Areas with moderate and high levels of potential
lands lide  dis as ters  are  more   prevalent  in  areas  that  experience   less intens ive land-us e change (IC). The area referred to can be s een from the A2-KI-B1  land unit covering 18,013,279   ha or 38.02%,  and the A3-KI- B1 land unit covering 10,491,693   ha or 22.15%  of the total area that has changed ie 47,366.81   ha. This s hows that the occurrence of lands lides in the Palolo s ub-dis trict was caus ed more by the weather (high rainfall)  in the Palolo s ub-dis trict.
INTERPOLTION OF SULFUR DIOXIDE (SO2) AND NITROGEN DIOXIDE (NO2 ) IN YOGYAKARTA SPECIAL PROVINCE USING THE COKRIGING METHOD
Authors: Aulia Pramesti Andina , Nur’eni  , Iman Setiawan
Published: August 2024

Air is a mixture of gases found in the layer that surrounds the earth. The cokriging method is the development of the kriging method to estimate a variable that minimizes estimation errors by utilizing cross-correlation between several variables. This research was conducted using data from 45 coordinate locations for air monitoring by the Department of Environment and Forestry of the Special Region of Yogyakarta in 2017. The results showed that the best model for estimating sulfur dioxide and nitrogen dioxide air pollution was the spherical model with the smallest Mean Square Error (MSE) value. which is 317,527. Interpolation of sulfur dioxide and nitrogen dioxide content values using cokringing resulted in 100,390 new points. The value of air pollution is in the range of 0-40, which according to ISPU means that at that point, good air quality has no impact on humans but causes a certain smell and injury to some plant species.
DETERMINATION OF SEISMIC VULNERABILITY INDEX AND SEDIMENT THICKNESS USING THE HVSR METHOD IN PALU CITY AREA
Authors: S Marwah , Rusydi M  , Kurniawan M  , Efendi Rustan , Rusli M  , E Sesa
Published: August 2024

The Palu City area is one of the areas that are vulnerable to the impact of the earthquake, seen from the seismicity and the Palu-Koro fault. Therefore, it is necessary to analyze the seismic vulnerability index and the thickness of the sediment layer in the Palu city area. This study uses the microtremor method with HVSR (Horizontal to Vertical Spectrum Ratio) analysis. The HVSR method produces natural frequency parameters (fo) and amplification (Ao) which are presented in the form of an H/V curve so that this method can estimate the seismic vulnerability index (Kg). The H/V then becomes the input for the ellipticity curve analysis to get the thickness of the sediment layer (h). The results of the study show that the Kg value ranges from 0.16 to 37.09. The lowest Kg value is located at the point MP2234-14 (Kawatuna Village). ) and the highest Kg value is located at MP2234-06 (Petobo Village), the high Kg value tends to be in the valley area and areas close to the coast, while the hillside tends to be low. The results of the analysis of the thickness of the sediment layer (h) ranged from 7 m to 128 m, the thick sediment layer is in the valley and coastal areas, while the thin sediment layer tends to be in the area oh the hills
POLÍTICAS PÚBLICAS EDUCACIONAIS E AS CONTRADIÇÕES DO ENSINO MÉDIO BRASILEIRO: AS INFLUÊNCIAS DA TEORIA DO CAPITAL HUMANO NA EDUCAÇÃO BRASILEIRA
Authors: Souza Maysa Andrade de , Alves João Paulo da Conceição , Souza Keline do Socorro Rodrigues de
Published: August 2024

O artigo apresenta como tema: o Ensino Médio (EM), última etapa da educação básica brasileita. Com objetivo geral de analisar o ensino médio brasileiro e suas contradições. Base teórico-metodológica é o Materialismo Histórico-dialético, o tipo de abordagem qualitativa. É importante ressaltar que os caminhos para a compreensão das políticas educacionais brasileiras voltadas ao Ensino Médio apresentam desafios. A análise das influências da TCH na educação brasileira é um deles. A realidade educacional do país que é marcado pela desigualdade social e divisão de classes, encontra no capitalismo modelos que reforçam ainda mais a dualidade marcante dessa etapa. Caracterizamos a TCH para compreender as formas que algumas políticas educacionais são pensadas e desenvolvidas. É o caso do Novo Ensino Médio (NEM), orientado pelo Lei n. 13.415/2017, uma política de reformulação de uma etapa significativa para a formação de novos trabalhadores/estudantes do Ensino superior no Brasil.
Ethnosciences learning related to socio-scientific issues: Problems asked, science answered
Authors: Tsaniyah Salma Putri , Fadly Wirawan
Published: August 2024

This study employs both quantitative and qualitative methods within an experimental setting. The study was conducted at Ma'arif 1 Junior High School in Ponorogo and focused on the influence of ethnoscience-based learning in ecology. The findings indicate a significant improvement in students' learning activities and their ability to address real environmental problems. Pre-test and post-test analyses revealed a substantial difference in learning outcomes, affirming that the integration of ethnoscience and social issues can enhance students' understanding and application of scientific knowledge in real and current contexts. This research implies the efficacy of ethnoscience as an effective means in science education to enhance students' scientific literacy and ecological awareness.
An analysis of Technological, Pedagogical, and Content Knowledge (TPACK) competencies of mathematics teachers in Sumatra in terms of gender
Authors: Sepriyanti Nana , Aniswita Aniswita , Wahida Deni
Published: August 2024

This research aims to analyze the TPACK competencies of mathematics teachers in Sumatra based on gender differences. Using a sequential explanatory mixed method approach, this study collected data through questionnaires and interviews to test hypotheses using two-way analysis of variance (ANOVA). The results indicate that mathematics teachers in Sumatra have a high level of TPACK competencies, with gender influencing the pedagogical knowledge and content knowledge domains. Specifically, male teachers exhibit higher competency in these domains compared to their female counterparts. Additionally, male teachers more frequently utilize technology in teaching and exhibit greater variability in integrating TPACK compared to female teachers. The implication of this research provides valuable insights for the development of teacher training programs that consider gender factors in enhancing TPACK competency, which is crucial for effective technology integration in mathematics education.
Unveiling the needs for ethnoscience-based e-worksheets to enhance nature of science and environmental awareness of elementary school students
Authors: Pratiwi Wulan Octi , Sunyono Sunyono , Rohman Fatkhur , Firdaus Rangga
Published: August 2024

This study aims to describe the analysis of the development needs of an ethnosciences-based e-worksheet. The research utilizes the 4D Research and Development model, specifically focusing on the define stage, which employs descriptive data analysis techniques. The research instruments consist of interviews with natural and social sciences teachers and questionnaires assessing the needs of both teachers and students. A preliminary study involved 136 students and 5 natural and social sciences teachers from 5 Elementary Schools in Bandar Lampung. The teachers' needs questionnaire results indicate that 100% of the teachers have not yet integrated natural and social sciences learning by connecting science knowledge with local Lampung culture. Similarly, the student's needs questionnaire shows that 89% have not experienced natural and social sciences learning integrated with Lampung's local culture. Furthermore, based on the results of the students' and teachers' needs questionnaires, 84% of the students answered "yes," indicating they strongly agree, and 100% of the teachers also answered "yes," indicating strong agreement, regarding the potential development of ethnosciences-based e-worksheet. This study implies the importance of instructional materials integrating local wisdom to enrich the learning process, support scientific literacy, and enhance environmental awareness.
The implementation of integral concepts in physics problem-solving by students with a conceptual blending framework approach
Authors: Fitriah Fitriah , Sugiatno Sugiatno , Noviani Evi
Published: August 2024

This research employed a qualitative descriptive approach to explore the application of integral concepts in solving physics problems with the conceptual blending framework. The sample of 26 students were categorized into four groups. The research investigated how different groups applied conceptual blending in addressing physics problems involving integrals. The findings revealed diverse understandings and approaches across the groups, with Group 4 exhibiting a more integrated understanding of physics and mathematics concepts. The study highlighted the effectiveness of conceptual blending in fostering a deeper comprehension of complex concepts in physics and mathematics, suggesting a potential pedagogical strategy to enhance students' problem-solving skills and theoretical understanding. This research contributes to the field by demonstrating the nuanced ways students engage with interdisciplinary concepts, offering insights for educators to refine teaching methodologies in integrating mathematics into physics education.
Empowering minds: How guided inquiry enhances scientific reasoning in students with varied self-efficacy levels
Authors: Diani Rahma , Asyhari Ardian , Putri Lia Pebriana
Published: August 2024

This study aims to determine the influence of the guided inquiry learning model on scientific reasoning abilities in students with high self-efficacy, moderate self-efficacy, and low self-efficacy categories. The method used is a quantitative approach with a quasi-experimental research type. The population was all of tenth-grade IPA (Natural Science) students. The samples taken were class XI IPA 1 and class XI IPA 2, determined with the simple random sampling technique. The research instrument consisted of description items to measure scientific reasoning ability and twenty Likert scale questionnaire items to measure student self-efficacy. The hypothesis test was conducted using the ANCOVA (Analysis of Covariance) test. Based on the hypothesis test result, the guided inquiry learning model influences students' scientific reasoning abilities with high self-efficacy, moderate self-efficacy, and low self-efficacy categories. The results of this research have several important implications for the development of educational practices, especially in science learning.
Association of local bioimpedance analysis of the abdominal region with morphological and biochemical traits
Authors: Bondareva EA , Leonov GE , Parfenteva OI , Arutiunian AA , Bevziuk NA , Kovaleva ON , Gadzhiakhmedova AN , Shemyakov SE , Kulemin NA
Published: August 2024

Quantification of the subcutaneous and visceral fat depot in the abdominal region is a promising method to assess individual risk of cardiometabolic disorders and estimate the efficacy of certain drugs. The local bioimpedance analysis (BIA) represent a new promising method for separate quantification of two fat depots in the abdominal region. The method combines high accuracy, low cost, and noninvasiveness. The study was aimed to analyze the relationships between the impedance estimates obtained in the local BIA lead and the complex of anthropometric and biochemical characteristics in males and females. A total of 147 females and 42 males aged 18–73 years were assessed. To estimate subcutaneous fat, we used the local BIA lead (АВС-02 Medass) in accordance with the earlier proposed electode placement scheme. Local impedance (Z50sc, Ohm) was recorded using the АВС-02 Medass software. The correlation analysis revealed significant correlations of Z50sc with the waist-to-height ratio, insulin concentration, body fat percentage, and HOMA-IR. Markers of the risk of cardiometabolic diseases (abdominal obesity, insulin resistance, and body fat percentage) are associated with the increased Z50sc values. The results of ROC analysis with the insulin resistance index (AUC 0.79 [0.72; 0.84], p < 0.000) make it possible to consider Z50sc a promising marker of the risk of cardiometabolic diseases. The differences between subgroups are confirmed by both statistical significance and large effect size.
Svyaz' lokal'noj bioimpedansometrii v abdominal'noj oblasti s ee morfologicheskimi i biohimicheskimi priznakami
Authors: Бондарева Э. А. , Леонов Г. Е. , Парфентьева О. И. , Арутюнян А. А. , Бевзюк Н. А. , Ковалева О. Н. , Гаджиахмедова А. Н. , Шемяков С. Е. , Кулемин Н. А.
Published: August 2024

Kolichestvennoe opredelenie podkozhnogo i visceral'nogo depo zhira v abdominal'noj oblasti yavlyaetsya perspektivnym metodom ocenki indvidual'nyh riskov razvitiya kardiometabolicheskih zabolevanij i ocenki effektivnosti nekotoryh lekarstvennyh preparatov. Lokal'nye otvedeniya bioimpedansometrii (BIA) — novyj perspektivnyj metod razdel'noj kolichestvennoj ocenki dvuh depo zhira v oblasti zhivota. On sochetaet vysokuyu tochnost', nevysokuyu sebestoimost' i neinvazivnost'. Cel'yu raboty bylo provesti analiz svyazej impedansnyh ocenok, poluchennyh v lokal'nom otvedenii BIA s kompleksom antropometricheskih i biohimicheskih harakteristik u muzhchin i zhenshchin. Obsledovany 147 zhenshchin i 42 muzhchiny v vozraste 18–73 let. Dlya ocenki podkozhnogo zhirootlozheniya ispol'zovali lokal'noe otvedenie BIA (AVS-02 «Medass») po predlozhennoj ranee skheme raspolozheniya elektrodov. Pri pomoshchi programmnogo obespecheniya AVS-02 «Medass» fiksirovali lokal'nyj impedans — Z50sc, Om. Korrelyacionnyj analiz vyyavil znachimye svyazi Z50sc s indeksom taliya/rost, koncentraciej insulina, procentom zhirovoj massy tela i HOMA-IR. Markery riska kardiometabolicheskih zabolevanij (abdominal'noe ozhirenie, insulinorezistentnost' i dolya zhirovoj massy) svyazany s povyshennymi znacheniyami Z50sc. Rezul'taty ROC-analiza s indeksom insulinorezistentnosti (AUC 0,79 [0,72; 0,84], p < 0,000) pozvolyayut rassmatrivat' Z50sc v kachestve perspektivnogo markera riska kardiometabolicheskih zabolevanij. Razlichiya mezhdu podgruppami podtverzhdayutsya ne tol'ko urovnem statisticheskoj znachimosti, no i znachitel'nym razmerom effekta.
Bibliometric Analysis of the Scientific Production in Cultural Tourism from 2010 to 2019 in Europe
Authors: Caicedo-Barreth Alba , Pavón Enrique Santos , Santos Luís Lima
Published: August 2024

This paper provides a general review of cultural tourism as a research subject in the last decade in Europe. First, it defines the terminology and its dimensions. This is followed by the analysis of the scientific papers published in international journals between 2010 and 2019, available in the Web of Science (WoS) and Scopus databases, to ensure the inclusion of high-impact studies according to the bibliometric quality index. Through the quantitative analysis of 625 WoS articles and 765 Scopus articles using bibliographic coupling, co-citation and co-occurrence analysis, this publication provides a significant overview of the terms involved or related to cultural tourism and the proposed clustering for each term. This paper concludes with a discussion of the main trends identified, their characteristics and possible changes over time.
Sustainable Tourism: A Systematic Literature Review and Bibliometric Analysis
Authors: Sofia Loureiro Isabel , Costa Vânia , Malheiro Alexandra
Published: August 2024

The research aims to emphasise the significance of sustainable tourism and the topics it’s being associated with. It is also intended to analyse the shift in literature during the selected time. A bibliometric analysis was conducted on highly cited documents about the Topic “sustainable tourism” from 2017 to 2022, using the Web of Science database. The analysis involved examining the number of research papers, their respective journals, co-authorship, country of origin and keywords. The keywords “sustainable tourism”, “covid-19” and “tourism” were used more frequently in the 50 articles collected. The majority of the articles were published in 2020 and 2021, coinciding with the pandemic, which demonstrates the emerging focus on sustainability given by researchers in this period. By relying on a specific database and specifically selecting highly cited papers, the study was limited. However, preferring these papers aligns with the goal of this research. The literature review synthesises the themes and perspectives from different authors and the relevance given to sustainable tourism due to the COVID-19 pandemic. It identifies key trends and viewpoints in the field while recognising its limitations and provides visual information on the topic.
Motivations and satisfaction of tourists staying in homestays across Kashmir Valley
Authors: Dar Ajaz , Iqbal Danish , Bhat Sajad
Published: August 2024

This study explores the motivations and satisfaction levels of tourists choosing homestays in the Kashmir Valley, an area renowned for its natural beauty and cultural richness. Despite the growing popularity of homestays, little research has been conducted on understanding the driving factors behind their selection and the satisfaction derived from such stays in this unique context. Utilising primary data collected through surveys and interviews from a sample of tourists, this paper employs Structural Equation Modelling (SEM) and factor analysis to identify the underlying motivations for choosing homestays and to evaluate tourists’ satisfaction levels.

The findings reveal that cultural immersion, personalised experiences, and the desire for authentic local interactions are primary motivations for tourists opting for home-stays over traditional hotel accommodations. Satisfaction levels were significantly influenced by the quality of interaction with hosts, the comfort of the accommodation, and the ability to experience the local way of life. The study’s results contribute to the theoretical understanding of tourist behaviour in the context of homestays and offer practical implications for hosts and policymakers aiming to enhance the homestay experience in the Kashmir Valley. By addressing the gap in the literature, this research provides valuable insights into the sustainable development of homestay tourism in culturally and ecologically sensitive regions.
Researching destination branding in pandemic crises: A research agenda
Authors: Feijó Almeida Giovana Goretti , Almeida Paulo
Published: August 2024

COVID-19 posed challenges to all areas of society. This study aims to analyse the impact of COVID-19 on destination brand research between 2020 and 2022. Based on Scopus and Web of Science, the researchers analysed the impact of COVID-19 on destination branding research. Thus, the systematic literature review associated with the integrative review was the method used in the study. The combined research databases showed limited published research on COVID-19 and the investigated topic. It is surprising to see such a contrast in an area that has experienced continuous growth since 2005. This article is relevant for public policy planners, tourism professionals, researchers, and students interested in destination branding. It is still necessary to perform a study on the impact of COVID-19 on destination branding. It should compare the peak of the pandemic in 2020–2022 with the current situation in 2024. An in-depth case study would be an especially welcome addition to the literature. The COVID-19 pandemic has underscored the critical importance of destination brand management in addressing unprecedented challenges and crises.
Tratamento da depressão bipolar
Authors: Lafer Beny , Nery Fabiano G.
Published: August 2024

Embora o estado maníaco seja a condição definidora do diagnóstico de transtorno bipolar, o estado depressivo é a condição sintomática mais frequente na vida do paciente e o responsável pela maior parte da incapacitação e sofrimento gerados ao portador de transtorno bipolar (Goodwin & Jamison, 2007). Em um estudo de seguimento de 10 anos, pacientes com transtorno bipolar tipo I estiveram deprimidos em 31% do tempo, mais do que em mania (9%) ou em estados mistos (9%) (Judd et al., 2003a). Pacientes com transtorno bipolar tipo II estiveram em depressão em 50,3% do tempo, muito mais do que em hipomania (1,3%) (Judd et al., 2003b). Cerca de 50% dos pacientes com transtorno bipolar tem um episódio depressivo como a primeira manifestação da doença, e os episódios depressivos podem ser crônicos em 20% dos pacientes e serem mais refratários ao tratamento do que episódios maníacos ou hipomaníacos (Yatham et al., 2005). A depressão bipolar, seja o episódio depressivo, sejam os sintomas subsindrômicos, contribui ainda com grande parte da perda de funcionalidade e qualidade de vida do paciente com transtorno bipolar (Goodwin & Jamison, 2007).
Tratamento de manutenção no transtorno bipolar
Authors: Souza Fábio Gomes de Matos e , (GETA) Grupo de Estudos de Transtornos Afetivos
Published: August 2024

Porque fazer o tratamento de manutenção. Devido ao alto risco de recorrências e recaídas (o tempo para recaída é de três meses em 50% dos indivíduos) em pacientes com transtorno afetivo bipolar (TB), a terapia de manutenção é de extrema importância. As taxas de recorrência variam de 60-80% após descontinuação do uso do lítio ou terapia antipsicótica e 20-50% durante o curso do tratamento (1) Yatham et al., 2005). Como resultado, os objeti-vos do tratamento a longo prazo incluem não apenas prevenção de comportamento suicida e recorrência de episódios maníacos e depressivos, mas também melhorar sintomas sub-sindrômicos, aderência ao tratamento e qualidade de vida e reinserção social dos pacientes (Yatham et al., 2009). Comorbidades psiquiátricas como abuso de substâncias e sintomas psicóticos são fatores de risco para recorrência (Kemp et al., 2009).
Abordagens psicossociais
Authors: Bio Danielle Soares , Gomes Bernardo
Published: August 2024

Ao longo dos últimos anos, especialmente na última década, a avaliação de diversas abordagens psicoterápicas foi incluída na agenda de pesquisa do transtorno bipolar (TB) do humor. Se até o final da década de 90 existiam pouco mais de dois estudos controlados publicados na literatura, apenas nos últimos dois anos foram publicados ao menos 12 ensaios clínicos com utilização de grupo controle. Este grande crescimento pode ser explicado pela mudança de visão que se tinha em relação ao TB, que passou a considerar a presença de sintomatologia residual fora de episódios de humor (Judd et al., 2002), o enorme impacto na vida funcional dos indivíduos (Magliano et al., 2009) e o próprio custo social atribuível a doença (Fajutrao et al., 2009). Somado a isso, estudos recentes têm demonstrado que quanto maior o número de episódios de humor pior a resposta destes pacientes (Pacchiarotti et al., 2011) ao tratamento medicamentoso. Desta forma, novos esforços foram empregados no sentido de aumentar o período de remissão da doença e de melhorar o manejo de sintomas e problemas relacionados a ela. Dentro deste contexto, o uso de abordagens estruturadas que se destinam especificamente ao tratamento do TB começaram a ser desenvolvidas.
Fatores desencadeantes da síndrome do coração partido
Authors: Gonçalves Maria Luiza de Sousa , Nogueira Raquel Bezerra de Sá de Sousa , Nogueira Tiago Bezerra de Sá de Sousa
Published: August 2024

Objetivo: Analisar os principais fatores que podem levar ao aparecimento da Síndrome do Coração Partido. Métodos: Trata-se de uma revisão integrativa e para compor essa pesquisa, as bases de dados utilizadas foram U.S. National Library of Medicine (PubMed), Portal da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) e Science Direct. A busca foi realizada com os Descritores em Ciências da Saúde (DeCS): “Takotsubo Cardiomyopathy” e “Risk Factors” combinados através do operador booleano “AND”, sendo selecionados 16 artigos para esse estudo. Resultados: Quanto aos achados, foram explanados como fatores que contribuem para o aparecimento da Síndrome do Coração Partido: hemorragia subaracnóidea, relatada em 18,75% dos artigos, pós-menopausa em 25%, síndrome metabólica em 18,75%, COVID-19 em 31,25%, inflamação sistêmica em 6,25%, medicamentos em 31,25%, estresse emocional em 37,5% e Alzheimer em 6,25%. Considerações finais: Evidenciou-se que as áreas que englobam os principais fatores os quais podem desencadear a Síndrome do Coração Partido são as alterações patológicas, endócrino-metabólicas, inflamatórias e psíquicas.
O papel da PrEP na estratégia de prevenção contra o HIV
Authors: Arrais Gabriel Lira de Carvalho , Amoroso Marco Antônio Ribeiro , Amoroso Marcelo Henrique Ribeiro , Gaudard Ana Marcia Iunes Salles
Published: August 2024

Objetivo: Expor o atual cenário da prevenção da infecção pelo HIV no que tange ao uso da Profilaxia Pré-Exposição (PrEP). Revisão bibliográfica: PrEP é uma inovação farmacológica que permite ao usuário estar protegido quase que completamente contra a infecção pelo vírus HIV. Em adição aos métodos de prevenção previamente existentes, esse medicamento tem modificado a epidemiologia da transmissão do vírus em populações-chave, proporcionando um impacto positivo considerável para a saúde pública, mas ainda enfrenta barreiras à sua implementação e adesão tanto por sistemas de saúde quanto por usuários. A literatura descreve uma adesão moderadamente bem-sucedida, com substanciais lacunas advindas das limitações socioeconômicas, culturais e psicológicas inerentes à divulgação e o uso de uma droga contra o HIV. Considerações finais: Esse artigo apresenta a atual literatura sobre o uso, a adesão, a expectativa, a realidade e as atitudes sobre o PrEP. Pode ser considerado que o uso da profilaxia pré-exposição está cada vez mais disseminado, mas que ainda há muito potencial para implementação de programas mais robustos visando a diminuição da transmissão do HIV.
Perfil bacteriológico de superfícies de canetas odontológicas
Authors: Queiroz Ana Luiza Florencio Galvão de , Alves Gabriela Quirino , Brito Jenyffer Kyara Chaves , Silva Iran Alves da , Cordeiro Risonildo Pereira
Published: August 2024

Objetivo: Realizar um estudo sobre os perfis de bactérias presentes nas superfícies das canetas odontológicas. Métodos: Trata-se de uma revisão de literatura integrativa, que investigou a contaminação de canetas odontológicas, a partir de publicações científicas indexadas no Google Acadêmico, PubMed, LILACS e ScienceDirect, utilizando os descritores “Equipamentos Odontológicos de Alta Rotação”, “Bactérias”, “Contaminação” e “Esterilização” combinados com o operador booleano AND, nos idiomas português, inglês e espanhol, publicados de 2013 a 2023, cuja amostra final resultou em 6 artigos. Resultados: Entre as publicações selecionadas, as bactérias mais comumente encontradas foram Staphylococcus spp. e Pseudomonas spp. No Brasil, é comum usar álcool a 70% para desinfecção de canetas, porém tal método não se mostra tão eficaz, pois não elimina todos os tipos de microrganismos, especialmente esporos. Por isso, é importante seguir o protocolo recomendado, limpando e desinfetando os componentes das canetas. Conclusão: É crucial seguir rigorosamente as normas de biossegurança, evitando a contaminação e protegendo os pacientes, dentistas e equipe ao lidar com canetas odontológicas de alto potencial de contaminação.