bluuebunny/crossref_metadata_2025 huggingface dataset:
Transcultural parallels between children of migrant parents and hearing children of Deaf parents: a case report
Authors: de Montgrémier Marion Vu-Augier , Lachal Jonathan , Moro Marie-Rose
Published: November 2023

The authors have requested that this preprint be removed from Research Square.
Scattering of pump electromagnetic wave in Thermal Cluster Plasma
Authors: Tiwari Pawan K. , Sadhu Riddhima , Kumar Ravindra , Parmar K P S
Published: November 2023

The existence of sub-micron sized clusters in a gas jet plasma dramatically alters the dispersion equations for electromagnetic and Langmuir waves. When a strong laser travels through such a plasma, stimulated Raman scattering, or SRS, takes place. The electromagnetic pump in SRS excites a side band wave and a Langmuir wave. The pump's oscillatory velocity mixes with the density disturbance caused by the Langmuir wave to produce a non-linear current density that drives the side band. The pump and side band wave exert a ponderomotive force on the electrons generating the Langmuir wave. The Langmuir wave is influenced by the plasma frequency and the thermal velocity of the plasma electrons.The impact of temperature on a short pulse laser stimulated Raman Scattering in a gas jet is examined embedded with atomic clusters.Due to a rise in the coupling constant, the growth rate of SRS increases as cluster density and electron thermal velocity increase., and frequency of the plasma wave,.Simulations have been carried out on Mathematica Version 8 to obtain the Normalized growth rate of stimulated Raman back-scattered wave with respect to normalized cluster density
Preliminary Design of Detector Assembly for DIXE
Authors: Liu Jiejia , Wang Sifan , Jin Hai , Cui Wei
Published: November 2023

Diffuse X-ray Explorer (DIXE) is a proposed X-ray spectroscopic survey experiment for the China Space Station. Its detector assembly (DA) contains the transition edge sensor (TES) microcalorimeter and readout electronics based on the superconducting quantum interference device (SQUID) on the cold stage. The cold stage is thermally connected to the 50 mK ADR stage, and a Kevlar suspension is used to stabilize and isolate it from the 4 K environment. TES and SQUID are both sensitive to the magnetic field, so a hybrid shielding structure consisting of an outer Cryoperm shield and an inner niobium shield is used to attenuate the magnetic field. In addition, IR/optical/UV photons can produce shot noise and thus degrade the energy resolution of the TES microcalorimeter. A blocking filter assembly is designed to minimize the effects. In it, five filters are mounted at different temperature stages, reducing the probability of IR/optical/UV photons reaching the detector through multiple reflections between filters and absorption. This paper will describe the preliminary design of the detector assembly and its optimization.
“Hope at a Better Chance”: Perspectives on Genetic Counseling and Testing among Black Individuals with Prostate Cancer
Authors: Prindeville Breanne , Szymaniak Brittany M. , Greenberg Samantha E. , Murphy Adam B. , Ross Ashley E. , Duquette Debra
Published: November 2023

Introduction:
Black individuals have the highest prostate cancer (PCa) incidence and mortality rates of any racial or ethnic group. Racial disparities persist in the understanding and uptake of genetics services, while the perspectives of Black individuals with PCa regarding genetic counseling and germline genetic testing for inherited cancer risk (GC/GT) remains understudied.
Methods
This qualitative study explored attitudes, facilitators, and barriers to awareness, interest, and uptake of GC/GT among Black individuals with PCa. Eight individuals who self-identified as African American and/or Black with a personal history of PCa participated in individual telephone interviews using a semi-structured interview guide. Interview transcripts were analyzed using both an inductive and deductive coding approach, constant comparison, and selective coding.
Results
Five major themes were identified: (1) uncertainty surrounding personal relevance of GC/GT, (2) family influence and impact of GC/GT, (3) healthcare providers and institutions as gatekeepers of GC/GT, (4) community identity, influence, and impact of GC/GT, and (5) systemic barriers to GC/GT exemplify larger structural constraints. A key finding was the influence of community, a collective identity among Black individuals and a desire to benefit the Black community, in motivating research participation and pursuit of GC/GT to lessen racial disparities in PCa.
Discussion
Individual, interpersonal, institutional, community, and structural factors are both barriers and facilitators to awareness, interest, and uptake of GC/GT. Multilevel interventions such as communicating personal, familial, and community implications of GC/GT, improving patient-provider relationships and genetics education, and addressing systemic barriers are necessary to increase efficacy, utility, and equity in GC/GT.
Quantitative synthesis of microbe-driven acclimation and adaptation in wild vertebrates
Authors: Bideguren Garazi , Razgour Orly , Alberdi Antton
Published: November 2023

We conducted a quantitative systematic review to evaluate the scientific evidence for the contribution of gut microorganisms to the acclimation and adaptation capacity of wild vertebrate hosts. After screening 1974 publications, we scrutinised the 109 studies that met the inclusion criteria based on 10 metrics encompassing study design, methodology, and reproducibility. We found that so far published studies were not able to resolve the contribution of gut microorganisms due to insufficient study design and research methods for addressing the hypothesis. Our findings highlight the need to shift from observational studies to experimental manipulations, where fitness or related indicators are measured, coupled with an update in molecular techniques used to analyse microbial functions.
Hollow Fibre Membrane Contactors for CO2 Capture
Authors: Panziera Edoardo , Sai-Obodai Lois Sandra , Sam Yusif Rhule , Avor Esther Praise , Ghobadi Amir
Published: November 2023

Hollow fiber membrane contactors have emerged as an attractive and promising technology for post-combustion carbon dioxide (CO2) capture by contacting exhaust gas with amines. This study focuses on investigating the performance of a modularized PTFE hollow fiber membrane contactor developed by Ionada. Comparative analyses were conducted between Ionada's technology and a traditional packed bed column. Results from simulations indicate a remarkable 20% reduction in solvent regeneration requirement and a 28% decrease in amine losses when employing Ionada's contactor, while maintaining the same operating conditions and target CO2 removal as the packed bed column. Consequently, these findings translate into substantial operational cost savings for carbon capture processes. The simulation results were validated through experimental runs, revealing an average absolute deviation of only 4% when comparing CO2 mass flux. Furthermore, the technology exhibits scalability, as an increase in the number of modules allows for the treatment of flue gas streams with higher flowrates without necessitating a complete unit change. Notably, scaling up the system correspondingly enhances absorption efficiency.
Cirsium acaule SCOP. und Cirsium×rigens (AITON) WALLR. im Altkreis Salzwedel (Altmark)
Authors: Brennenstuhl Günter
Published: November 2023

Es werden die im Altkreis Salzwedel (Altmark, Sachsen-Anhalt) seit 1972 beobachteten Vorkommen von Cirsium×rigens (AITON) WALLR. beschrieben. Der Elter Cirsium acaule SCOP. wird wegen seiner Seltenheit im Untersuchungsgebiet in die Betrachtung einbezogen. Zu beiden Sippen folgen Angaben zu den Fundorten und Standortverhältnissen sowie zur Populationsentwicklung und Begleitflora.
Zur Einbürgerung von Vinca- und Miscanthus-Taxa – Beobachtungen im Gebiet um Salzwedel
Authors: Brennenstuhl Günter
Published: November 2023

-
Bunte Blumenwiesen – Erhöhung der Biodiversität oder Verstoß gegen Naturschutzrecht?
Authors: Frank Dieter , John Heino
Published: November 2023

Die Artenzusammensetzung von Ansaatgrünland in der freien Landschaft wurde beispielhaft überprüft. Es konnte die Etablierung sowohl von Kulturformen indigener Arten als auch fremder Taxa, wie Dianthus giganteus und Centaurea scabiosa ssp. fritschii, nachgewiesen werden.
Zur Unterscheidung von Dipsacus pilosus L. und Dipsacus strigosus WILLDENOW ex ROEMER et SCHULTES
Authors: Ahrens Wolfgang
Published: November 2023

-
Zur Situation von Armeria maritima ssp. hornburgensis – aktuelle Daten zu Populationsgröße, Demographie und Taxonomie
Authors: Baumbach Henryk , Volkmann Horst K. M.
Published: November 2023

Der vorliegende Beitrag gibt einen Überblick über die aktuelle Bestandssituation (September 2006) von Armeria maritima ssp. hornburgensis (A. SCHULZ) ROTHM. sowie demografische und genetische Parameter der Population. Aus diesen Daten werden Empfehlungen für kurz-, mittelund langfristige Schutz- und Pflegemaßnahmen zum Erhalt der Population abgeleitet. Zusätzlich wird die Taxonomie der Sippe im Kontext neuer molekulargenetischer Untersuchungen des gesamten mitteleuropäischen Armeria maritima-Komplexes diskutiert.
Biotoperfassung in der Tagebaufolgelandschaft des Osendorfer Sees (Halle/Saale)
Authors: Kästner Arndt , Schubert Rudolf
Published: November 2023

-
Bemerkenswerte Pflanzenfunde in Sachsen-Anhalt 2. Beitrag
Authors: Krumbiegel Anselm
Published: November 2023

-
Wiederfund von Eleocharis ovata (ROTH) R. et SCH. im Naturschutzgebiet „Heideteiche bei Osterfeld“, Burgenlandkreis
Authors: Löb Andreas
Published: November 2023

-
Bemerkenswerte Pflanzenfunde im Landkreis Sangerhausen
Authors: Hoch Armin
Published: November 2023

-
Zur Ausbreitung von Halophyten und salztoleranten Pflanzen in der Umgebung von Kali-Rückstandshalden am Beispiel des FND „Salzstelle bei Teutschenthal-Bahnhof“ (Saalkreis)
Authors: John Heino
Published: November 2023

-
Erfassung, Identifizierung, Vermehrung und Wiederansiedlung der Schwarzpappel Populus nigra in Sachsen-Anhalt
Authors: Natzke Ehlert
Published: November 2023

-
Brombeeren Sachsen-Anhalts (Gattung Rubus L. subgenus Rubus)
Authors: Pedersen Anfred , Stohr Gerrit , Weber Heinrich E.
Published: November 2023

-
Fritillaria meleagris am Quellhügel bei Vinzelberg (Altmarkkreis Salzwedel)
Authors: Krumbiegel Anselm
Published: November 2023

Im Jahr 2017 wurde ein bisher nicht beschriebenes Vorkommen der Schachblume bei Vinzelberg in der Altmark erfasst und hinsichtlich Bestandsgröße und Vergesellschaftung der Art untersucht. Es werden außerdem aktuelle Bestandsdaten zu einigen weiteren Vorkommen in der Altmark mitgeteilt.
Socioeconomic predictors of access to improved water sources, sanitation facilities, and household water treatment in Nigeria
Authors: Azeez Olumayowa , Henderson-Mitchell Randi J. , LaFevor Matthew C. , Gregg Abbey
Published: November 2023

In Nigeria, the widespread lack of access to water, sanitation, and hygiene (WASH) represents a critical public health challenge. Yet, the socioeconomic determinants of WASH access at the national level remain poorly understood. This study uses 2018 Nigeria Demographic and Health Surveys (NDHS) cross-sectional data to investigate the socioeconomic factors associated with WASH access. The majority of survey respondents lived in rural areas (57%); used an improved source of drinking water (73%) and an improved sanitation facility (55%); and did not treat their drinking water (92%). Binary logistic regression showed that Nigerians living in rural areas were less likely to have access to an improved water source (p < 0.001, OR = 0.42 [0.41, 0.44]) and less likely to have access to an improved sanitation facility (p < 0.001, OR = 0.79 [0.77, 0.81]). A sub-group regression analysis of respondents without access to improved WASH found that rural residence (OR = 0.84 [0.76, 0.93]), along with lower levels of education and wealth were associated with non-treatment of their unimproved drinking water. This study suggests that efforts are needed to increase WASH access in rural areas and to improve household water treatment in areas without access to improved water and sanitation.
WASH practices increased the prevalence of malnutrition among under-five children (6–59 months) in an urban slum area in Ibadan, Nigeria
Authors: Aleru Elizabeth Oluwafolakemi , Bodunde Ifeoluwa Omolara , Deniran Igbagboyemi Adesola , Nafisat Ajani Olajumoke , Aleru Oluwatobi Olayinka , Fawole Abisola Omotola
Published: November 2023

Access to safe water, proper sanitation, and hygienic practices are fundamental to the growth and survival of children. This study assessed the relationship between water, sanitation, and hygiene (WASH) practices and the nutritional status of children aged 6–59 months in the Beere/Oja-Oba community, Ibadan, Oyo State. This cross-sectional study involved 200 mothers/caregivers with under-five children. WASH practices were assessed using an interviewer-administered questionnaire. Anthropometric measurements were taken and analyzed using WHO Anthro. Data were analyzed using SPSS at p < 0.05. The mean age of the children was 24.91±10.52, and the majority were females (77.5%). Prevalence of stunting (44.0%), wasting (37.5%), and underweight (34.0%) were high among the children. Well (71.5%) and tap/borehole (74.0%) were the major sources of domestic and drinking water respectively, and required 5–15 min (36.9%) to source. The occurrence of diarrhea was high (48.5%) among the children. Time to drinking water source and washing a child's hands before feeding were WASH practices significantly associated with stunting (p = 0.000) and underweight (p = 0.003) among the children from lower socio-economic households (p = 0.045). Access to unsafe water was significantly associated with child malnutrition. There is a need to educate and encourage mothers/caregivers to improve their hygiene practices in the community.
How to Choose the Best Fragrance for Your Cosmetics
Authors: Minocha Sakshi
Published: November 2023

Background:

Some people may experience allergic responses like skin irritation and
rashes due to the seductive aroma of your attractive cosmetic products. The fragrance in your
cosmetic items can also lead to serious allergies like asthma and headaches, which may deter
customers from purchasing your cosmetics. The development of fragrances is a crucial component
of cosmetic formulation because it blends an aesthetic vision with knowledge of the chemistries
and dynamics of the scent materials.

Objective:

When launching a cosmetics company and having a product ready to sell, it is crucial
to take into account a number of elements, including the potency of the scent, the product's stability
in the presence of heat and light, the compatibility of the ingredients, and the effects of the
packaging. While certain compounds used in fragrances quickly disappear from the skin, others
cling to it for longer. In order to accomplish the intended outcome and produce a product that is
attractive to the eye, it is crucial for these qualities to interact over time. Buyer psychology is
impacted by fragrance in cosmetic products, which may influence whether or not a consumer
decides to purchase it.

Methods:

The study utilized a comprehensive review of existing literature, market research, and
industry insights to gather information on fragrance selection for cosmetics.

Results:

The results of the study indicate that choosing the best fragrance for cosmetics involves
considering several key factors. Firstly, understanding the specific product type is crucial, as different
cosmetics require different types of fragrances to match their purpose and intended use.
Secondly, considering the target audience's preferences is essential, as different demographics
have varying fragrance preferences. Thirdly, aligning the fragrance with the brand identity is important
to create a cohesive and consistent product experience.

Conclusion:

In conclusion, selecting the best fragrance for cosmetics requires a thoughtful and
strategic approach. By considering the product type, target audience, brand identity, and market
trends, cosmetics manufacturers can make informed decisions that enhance the overall product
experience and customer satisfaction.
Transformational Games as a Tool for Developing Students' Effective Communication Skills
Authors: Ivanova T. V. , Altunina E. V. , Danko O. A.
Published: November 2023

Purpose of the study. The skill of effective communication is not only the most important component in the activities of a qualified specialist, but also makes everyday communication more trusting, less aggressive and dependent. This is confirmed by the research of domestic and foreign scientists, business coach programs, and the practical work of coaching and consulting specialists. The purpose of our work is a theoretical and experimental study of the use of transformational games as a tool for developing students' effective communication skills. The article examines the skill of effective communication of students according to various criteria. The results of the application of the program for the development of effective communication skills of students using transformational games are shown.

   Methods. The methodology of «Diagnostics of communicative tolerance» by V. V. Boyko is designed to determine to what extent people are able to show tolerance to other people in business and interpersonal communication. The test «Communicative skills» of Mikhelson L. in the modification of Gilbukh Y.Z. we used to determine the level of communicative competence and the quality of formation of basic communicative skills. To study the ability to showempathy, the «Emotional Response Scale» technique is used (A. Mehrabyan, modification by N. Epstein). In the formative part of our work, we used transformational negotiation games «The Red Rose Effect. The best techniques of persuasion» and «Say NO».

   Results. it was revealed that a significant number of students have difficulties in managing emotions that negatively affect interpersonal communication. Testing showed that the majority of students have an average level of general communicative tolerance. Students use aggressive (oppressive behavior) and dependent (insecure behavior) positions in communication. A significant number of students demonstrate a low level of response with feelings, which makes it difficult to contact people around them.

   Conclusion. Thus, purposeful work is needed to develop students' communication skills. For this purpose, we have developed a program for developing students' effective communication skills using transformational games, the effectiveness of which has been proven in practice and statistically.
Ways to Create a Negative Image of Russia in Georgia's Political Discourse
Authors: Akhmetgareeva O. F.
Published: November 2023

The importance of this study due to the direct linkage of such issues to the priority directions of development of modern anthropocentric and functionally oriented linguistics that contributes to scientific interest in the study of language and issues of speech influence on the consciousness of individuals, including the explicit form of exposure. This article discusses some ways of creating the image of Russia in political discourse of modern Georgia in interstate conflict that is actively used in information war and implemented by the use of the tactic of creating an enemy image, which appears to be the highest form of discrediting Russia's image. The paper highlights the features of the functioning of language tools used in the technology of demonization of the enemy, taking into account factors such as the situation of communication, its characteristics. Proper use of methods of speech influence, their expressive capabilities helps to achieve the desired result. This study is relevant for specialists engaged in the study of discourse, national and linguistic and cultural features of political discourse, as well as for those interested in ways to create negative images of the likely enemy of the mass addressee.
Experimentally Induced Reductions in Alcohol Consumption and Brain, Cognitive, and Clinical Outcomes in Older Persons With and Those Without HIV Infection (30-Day Challenge Study): Protocol for a Nonrandomized Clinical Trial
Authors: Cook Robert L , Richards Veronica L , Gullett Joseph M , Lerner Brenda D G , Zhou Zhi , Porges Eric C , Wang Yan , Kahler Christopher W , Barnett Nancy P , Li Zhigang , Pallikkuth Suresh , Thomas Emmanuel , Rodriguez Allan , Bryant Kendall J , Ghare Smita , Barve Shirish , Govind Varan , Dévieux Jessy G , Cohen Ronald A ,   The 30-Day Challenge Research Team
Published: November 2023

Background

Both alcohol consumption and HIV infection are associated with worse brain, cognitive, and clinical outcomes in older adults. However, the extent to which brain and cognitive dysfunction is reversible with reduction or cessation of drinking is unknown.

Objective

The 30-Day Challenge study was designed to determine whether reduction or cessation of drinking would be associated with improvements in cognition, reduction of systemic and brain inflammation, and improvement in HIV-related outcomes in adults with heavy drinking.

Methods

The study design was a mechanistic experimental trial, in which all participants received an alcohol reduction intervention followed by repeated assessments of behavioral and clinical outcomes. Persons were eligible if they were 45 years of age or older, had weekly alcohol consumption of 21 or more drinks (men) or 14 or more drinks (women), and were not at high risk of alcohol withdrawal. After a baseline assessment, participants received an intervention consisting of contingency management (money for nondrinking days) for at least 30 days followed by a brief motivational interview. After this, participants could either resume drinking or not. Study questionnaires, neurocognitive assessments, neuroimaging, and blood, urine, and stool samples were collected at baseline, 30 days, 90 days, and 1 year after enrollment.

Results

We enrolled 57 persons with heavy drinking who initiated the contingency management protocol (mean age 56 years, SD 4.6 years; 63%, n=36 male, 77%, n=44 Black, and 58%, n=33 people with HIV) of whom 50 completed 30-day follow-up and 43 the 90-day follow-up. The planned study procedures were interrupted and modified due to the COVID-19 pandemic of 2020-2021.

Conclusions

This was the first study seeking to assess changes in brain (neuroimaging) and cognition after alcohol intervention in nontreatment-seeking people with HIV together with people without HIV as controls. Study design strengths, limitations, and lessons for future study design considerations are discussed. Planned analyses are in progress, after which deidentified study data will be available for sharing.

Trial Registration

ClinicalTrials.gov NCT03353701; https://clinicaltrials.gov/study/NCT03353701

International Registered Report Identifier (IRRID)

DERR1-10.2196/53684
Case-Based Serious Gaming for Complication Management in Colorectal and Pancreatic Surgery: Prospective Observational Study (Preprint)
Authors: Schwarzkopf Sophie-Caroline , Distler Marius , Welsch Thilo , Krause-Jüttler Grit , Weitz Jürgen , Kolbinger Fiona R
Published: November 2023

BACKGROUND

The potential risk and subsequent impact of serious complications after pancreatic and colorectal surgery can be significantly reduced through early recognition, correct assessment, and timely initiation of appropriate therapy. Serious gaming (SG) is an innovative teaching method that combines play with knowledge acquisition, increased concentration, and quick decision-making and could therefore be used for clinically oriented education.

OBJECTIVE

This study aims to develop a case-based SG platform for complication management in pancreatic and colorectal surgery, validate the application by comparing game courses of various professional groups in the health care sector, and test the acceptance of the developed platform in the context of clinical education by measuring levels of usability and applicability within the framework of a validity and usefulness analysis.

METHODS

In this observational trial, a novel SG for management of postoperative complications was developed and prospectively validated in a cohort of 131 human caregivers with varying experience in abdominal surgery. A total of 6 realistic patient cases were implemented, representing common complications after pancreatic and colorectal surgery. Cases were developed and illustrated using anonymized images, data, and histories of postoperative patients. In the prospective section of this study, following a brief case presentation, participants were asked to triage the virtual patient, make an initial suspected diagnosis, and design a 3-step management plan, throughout which the results of selected diagnostic and therapeutic actions were presented. Participants’ proposed case management was compared to ideal case management according to clinical guidelines. Usability, applicability, validity, and acceptance of the application were assessed using the Trier Teaching Evaluation Inventory as part of a noncomparative analysis. In addition, a comparative analysis of conventional teaching and learning formats was carried out.

RESULTS

A total of 131 cases were answered. Physicians selected more appropriate therapeutic measures than nonphysicians. In the Trier Teaching Evaluation Inventory, design, structure, relevance, timeliness, and interest promotion were predominantly rated positively. Most participants perceived the application to be superior to conventional lecture-based formats (training courses, lectures, and seminars) in terms of problem-solving skills (102/131, 77.9%), self-reflection (102/131, 77.9%), and usability and applicability (104/131, 79.4%).

CONCLUSIONS

Case-based SG has educational potential for complication management in surgery and could thereby contribute to improvements in postoperative patient care.
The Effect of Friend Support and Family Support on the Adjustment of First Year College Students
Authors: Dubey Paulmi , Soni Dr. Siddharth
Published: November 2023

Abstract: Adjustment is the process of adapting to changes in the environment, which may be mental, physical and occupational. It also refers to being able to balance out conflicting needs, or bringing back the state of homeostasis. A well adjusted person is able to adapt to their surrounding efficiently, in a healthy way and is able to perform the tasks expected of them, and are able to have valuable contributions towards their friends, family, peers and the society at large. It was found that both family support and peer support were positively correlated to the overall adjustment of first year college students. However, family support and adjustment had a higher correlation (0.266) as compared to the correlation between friends support and adjustment ( 0.259). This can be alluded to the fact that India is a collectivistic country, and family support and values have a higher priority than the support of friends and acquaintances.
Manifestation of Hadiths in Environmental Preservation
Authors: Nuraini Nuraini
Published: November 2023

Humans and the environment are inseparable partners. The environment is our home, where we live and interact with everything around us, both living and non-living. Allah SWT has created this environment to meet our needs, as we depend on it for our survival. This shows how crucial it is for us to treat our environment wisely, ensuring it can continue supporting us. However, not everyone treats the environment wisely. Sometimes people prioritize their own interests without considering the long-term health of nature. This can lead to resources running out or becoming damaged. This article explores how the teachings of Prophet Muhammad SAW guide us in preserving the environment, both through what he said and what he did. Prophet Muhammad SAW’s guidance encourages us to act responsibly when using the environment. These teachings also highlight that we are responsible for taking care of the environment, as Allah SWT has chosen us to look after it. Allah SWT knows that humans can be greedy and harm nature. So, Allah SWT has rewards and consequences based on how we treat the environment. When we follow Islamic teachings, we are rewarded, and when we disregard them, there are consequences. Following these teachings means thinking about the environment’s long-term well-being. It means taking positive care of nature so that all of Allah SWT’s creations—living things and the environment—can thrive. Ultimately, this approach benefits us, leading to a complete, beautiful, peaceful, healthy, and refreshing environment
Competencies for managing green buildings: aligned components from malaysia's facilities management service provider
Authors: Ishak Mohd Hafizal , Ismail Siti Nur Ayunie , Md. Yassin Azlina , Ahmad Nurul Afiqah
Published: November 2023

The increased development of green buildings in Malaysia has necessitated the need for facility management businesses to upgrade their competencies. However, as evidenced by past studies, a shortage of competences among practitioners has emerged as an uncertainty about firms' capacity for managing green buildings. Therefore, the purpose of the research is to acquire insight into the competency features of FM service providers in Malaysia for managing green buildings and to make recommendations for competency improvement. The qualitative approach was adopted, and interview was used to achieve the goals, the data was examined using content analysis. Based on the experiences of seven (7) managers who have managed green buildings, the five (5) core strengths of facilities management service providers in managing green buildings are sustainable procurement, operations, resource management, repair and maintenance, and environmental health. This study demonstrated common themes between facilities management and green building management competencies.
Revitalization of Colonial Buildings as Community Centre: Case study of the Former Radio Cililin Building, Bandung, West Java, Indonesia
Authors: Nurrahman Hafiz , Purwatiana Rahmadean Alifani , Kusliansjah Yohanes Karyadi , Permana Asep Yudi
Published: November 2023

The historical remnants of the former Cililin Radio Transmitter area comprise the Cililin Radio Transmitter Building and the remnants of the Transformer Building, which served as tangible artifacts from the Dutch colonial era when it functioned as a radio transmission station. These remnants hold profound historical and archaeological significance, representing a bygone communication technology era. Cililin Radio Transmitter Building is interwoven with pivotal historical events, including the sovereignty transfer from the Netherlands to Indonesia in the Cililin region, and marks the inception of SMA N 1 Cililin (State Senior High School 1 Cililin). These structures' condition and surroundings were neglected, rendering them susceptible to deterioration. This led to the restoration and revitalization of this area to safeguard its historical value and make it accessible to the community. This design research aims to revitalize the former area. Cililin Radio Transmitter is a community center, where the process begins with studies related to revitalization to obtain design parameters that can be applied to the case. Therefore, this research and design will transform the former Cililin Radio Transmitter Area into a vibrant community center. A creative metaphorical approach was employed, which ensured the preservation of the buildings, amplification of the historical essence of the site, and the provision of community-oriented facilities. A qualitative method was used to analyze the objects through field surveys connected with literature related to revitalization and metaphorical architecture. The results showed that the adaptation and addition of new functions to the study objects rejuvenated the environment and accommodated the community's social activities.
Thermal Comfort and Microclimate in Indoor Spaces of Low-rise Residential Buildings in Dry Tropical Climate
Authors: Therán-Nieto Kevin , Pérez-Arévalo Raúl , Marín-Carranza Jesús , Caballero-Calvo Andrés
Published: November 2023

The aim of this research is to analyze thermal comfort and microclimate for indoor spaces in low-rise residential buildings in dry tropical climate. The study area is the municipality of Palmar de Varela in northern Colombia. The experimental methodology is based on measuring three microclimatic parameters: air temperature (Ta), relative humidity (RH) and natural ventilation (W). The study assessed the thermal sensation in indoor spaces based on Thermal Sensation Vote (TSV) and Predicted mean vote (PMV). Data gathered from surveys were analyzed with data mining technologies. The findings suggest that suspended ceilings and ceramic tiles aid to the thermal equilibrium of the building, resulting in a 1.1 °C decrease in indoor air temperature. Likewise, the correlation between temperature and wind (r = -0.72; -0.56) indicates that natural ventilation in buildings can alleviate thermal discomfort. Based on the thermal sensation evaluation, the predominant feeling reported by interviewees in indoor spaces was warm (2) in S1 and S2, and slightly warm (1) in S3. In addition, the correlation between air temperature and comfort sensation in indoor spaces (r = 0.64; 0.44) suggests that temperature has a direct impact on thermal sensation votes.
Program pendampingan ibu rumah tangga dalam meningkatkan ketahanan keluarga pasca bencana gempa Cianjur
Authors: Widiastuti Novi , Nugraha Arya , Firmansyah Fiqri , Herrianto Herrianto , Rochman Mochamad Nur , Sazidan Muhammad Nizar , Permana Yuda Hakim
Published: November 2023

Bencana gempa yang menimpa Kab. Cianjur memberikan dampak yang sangat berarti, salah satunya adalah runtuhnya ketahanan keluarga. Ketahanan keluarga pada aspek fisik dan psikis tentunya menjadi sebuah kehrusan untuk dimiliki setiap keluarga dalam menghadapi berbagai tantangan hidup yang tidak pasti. Kehilangan anggota keluarga tentunya sangat memberikan efek negatif pada ketahanan keluarga, apalagi kehilangan kepala keluarga. IKIP SIliwangi melalui program Gerakan IKIP Siliwangi Mengajar (Gisma) tahun 2023 melakukan pendampingan terhadap keluarga yang terdampak gempa secara langsung. Dengan metode pendampingan, pelatihan, dan trauma healing, diharapkan dapat memberikan warna baru dalam membantu korban bencana gempa melalui pengabdian pada masyarakat yang terintegrasi dengan kegiatan mahasiswa. Materi yang disampaikan dalam pendampingan adalah program parenting dan trauma healing melalui kegiatan Surat Cinta Untuk Diriku. Adapun hasil yang didapat adalah adanya semangat para ibu untuk bangkit dari bencana demi mempertahankan keutuhan keluarga dan perluasan aksesibilitas terhadap layanan konsultasi pengasuhan anak.Kata Kunci : Parenting , Pendampingan Keluarga, Ketahanan Keluarga
CRITICAL PLAYGROUND AS PLAY-CE UTOPIA. (MANIFESTO FOR A DIFFERENCE IN ITSELF.)
Authors: Anartist
Published: November 2023

City of Panic is an urban intervention, which has been realized by The Anartist (Gian Luigi Biagini and John Dunn). It happened in 2019 in the central train-station square of Helsinki. The installation-performance is a "caged mini-golf", which catches and elicits many disruptive resonances. The intervention challenges, contests and makes visible the "iron cage of rationality" that organizes the capitalist urban space through an ordoliberal trans-institutional consensus that does not leave space for the expression of Difference. The intervention puts in "play-ce" a critical and mystic playground of Difference in Itself that breaks the cage of assimilation to a functional hierarchical identity. The article describes this complex experience of rupture and cata-comic rapture by a phenomenology of the process in becoming. A phenomenology and an ethnography of difference, with theory references "in flight", that cannot be completely grasped by a homogenous and unified signifier, narrative, representation. Even the style of the graphic tries to evoke this "virtual heterogeneity of intertwined planes and becomings" that are sutured and re-composed by creative writing.
Constructing a database of alien plants in the Himalaya to test patterns structuring diversity
Authors: Rana Suresh , Dangwal Bhawana , Rawat G.S. , Price Trevor
Published: November 2023

Differences in the number of alien plant species in different locations
may reflect climatic and other controls that similarly affect native
species and/or propagule pressure accompanied with delayed spread from
the point of introduction. We set out to examine these alternatives for
Himalayan plants, in a phylogenetic framework. We build a database of
alien plant distributions for the Himalaya. Focusing on the well
documented regions of Jammu & Kashmir (west) and Bhutan (east) we
compare alien and native species for (1) richness patterns, (2) degree
of phylogenetic clustering, (3) the extent to which species-poor regions
are subsets of species-rich regions, and (4) continental and climatic
affinities/source. We document 1,470 alien species (at least 600
naturalised), which comprise ~14% of the vascular
plants known from the Himalaya. Alien plant species with tropical
affinities decline in richness with elevation and species at high
elevations form a subset of those at lower elevations, supporting
location of introduction as an important driver of alien plant richness
patterns. Separately, elevations which are especially rich in native
plant species are also especially rich in alien plant species,
suggesting an important role for climate (high productivity) in
determining both native and alien richness. We find no support for the
proposition that human disturbance or resistance to invasion by native
species affect alien distributions. Results imply an ongoing expansion
of alien species from low elevation sources, some of which are highly
invasive.
Robots in Mine Search and Rescue Operations: A Review of Platforms and Design Requirements
Authors: Androulakis V. , Bakzadeh R. , Khaniani H. , Shao S. , Hassanalian M. , Roghanchi P.
Published: November 2023

The use of automation in mining can be found at all stages of the mining
process, covering exploration, excavation, loading, transportation,
mineral processing, and search and rescue missions in emergency
situations. Due to the harsh conditions during an underground mine
disaster, robots can be of great assistance to rescue teams by entering
areas that are unsafe for human rescuers, locating trapped workers and
collecting valuable data. The design and implementation of mine rescue
robots is characterized by great complexity since it encompasses the
consideration of a great range of components and requirements. However,
comprehensive guidelines for design and deployment of robots in harsh
underground environments have not been established. As a result, the
developers of mine rescue robots (MRRs) are to exercise their own
judgment on the development and evaluation of the platform
functionalities. This review attempts an extensive discussion of design
and functionality requirements based on the common practices and lessons
learned from the existing MRRs. Common considerations, as well as
current and future trends are identified with the aim of facilitating
future research and development on mine search and rescue robots.
GM3 Ganglioside’s Efficacy in LPS-Induced Parkinsonism: Neuroprotection and Gliosis Mitigation
Authors: Liu Tsung-Ta , Fann Li-Yun , Li I-Hsun , Hsiao Sheng-Huang , Chu Yu-Chieh , Hung Hao-Yuan , Cheng Chih-Chien , Huang Ying-Che , Chiu Chuang-Hsin , Chou Ta-kai , Shih Jui-Hu
Published: November 2023

Background: Parkinson’s disease (PD) continues to be a neurological
challenge with limited therapeutic options. This study aimed to
investigate the potential therapeutic effects of GM3 ganglioside,
focusing on its role in mitigating LPS-induced parkinsonism behaviors,
gliosis, and neurotoxicity. Methods: We employed a range of in vivo
tests, including rotarod and beam-walking, to assess motor function
improvements in LPS-induced parkinsonism following GM3 ganglioside
pre-treatment. Dopaminergic neurotoxicity was examined using
[18F]FE-PE2I PET imaging and TH staining of the striatum. Further,
we investigated the impact of GM3 ganglioside on LPS-induced gliosis by
observing changes in microglial activation and astrocytic proliferation.
Results: Pre-treatment with GM3 ganglioside significantly improved motor
functions, as evidenced by enhanced performance in rotarod and
beam-walking tests. Our findings also showcased GM3 ganglioside’s
efficacy in countering LPS-induced dopaminergic neurotoxicity, with
[18F]FE-PE2I PET imaging and TH staining supporting its
neuroprotective potential. Importantly, GM3 ganglioside pre-treatment
notably reduced LPS-induced gliosis, demonstrating a significant
decrease in both microglial activation and astrocytic proliferation.
Conclusions: GM3 ganglioside presents promising neuroprotective
capabilities, effectively mitigating LPS-induced parkinsonism behaviors
and gliosis. These findings underscore GM3 ganglioside’s potential as a
valuable therapeutic avenue for future Parkinson’s disease
interventions.
Comparative analysis of echocardiographic and clinical characteristics among patients afflicted by embolic stroke of undetermined source and migraine, both accompanied by patent foramen ovale
Authors: Polat Fuat , Kaya Zeynettin , yaylak barış , Onuk Tolga
Published: November 2023

Background: This study aimed to compare patients with migraine
and embolic stroke of undetermined source (ESUS) with known patent
foramen ovale (PFO) in terms of echocardiographic and clinical features.
Methods: In this observational single-center study, we obtained
2-dimensional (2D) and color Doppler images using parasternal short axis
(PSAX), apical 4-chamber (A4C), and subcostal 4-chamber (SC4C)
transthoracic echocardiography (TTE) views for patients with Migraine
and ESUS. In cases where a PFO was suspected, patients underwent
transthoracic contrast echocardiography and transesophageal
echocardiography (TEE). We compared the anatomical and functional
high-risk characteristics of PFO, as assessed by TEE and the RoPe score,
in both patient groups. Results: This research involved a
cohort of 720 individuals with ages ranging from 18 to 60, and 73.2% of
the participants were female. Among the participants, 43.5% had
Migraine, and 56.5% had ESUS. The most common comorbidity was diabetes
(26.1%). PFO characteristics were measured, and high-velocity shunting
through the interatrial septum was observed in 35.5% of patients. ESUS
patients had a higher median age, with a similar gender distribution.
ESUS patients had higher rates of diabetes and hypertension, while
active smoking was more common in Migraine patients. Basic
echocardiographic parameters were similar, except for higher pulmonary
artery systolic pressure in ESUS. In the ESUS group, as compared to the
migraine group, there was a more substantial occurrence of large
microbubble passage through the interatrial septum, and the PFO showed
increased length, while the PFO width remained similar. The RoPe and
High-risk PFO scores were similar between the groups.
Conclusions: ESUS patients were older with higher rates of
diabetes and hypertension, while Migraine patients had a higher
prevalence of active smoking. ESUS patients showed elevated pulmonary
artery pressure, increased large microbubble crossings through the
interatrial septum, and longer PFO lengths.
He-A, a new natural [4 + 2] adduct, protects against neuronal damage through inhibiting ferroptosis via the Nrf2/SLC7A11 axis activation
Authors: Deng Jia-Le , Wang Guo-Yan , Zhai Yi-Jie , Feng Xu-Yao , Deng Lu , Han Wen-Bo , Tang Jiang-Jiang , Gao Jin-Ming
Published: November 2023

Background and Purpose: Neuroprotective strategy targeting ferroptosis
is currently considered a promising therapeutic approach for
neurodegenerative diseases (NDDs). Herpotrichones showed potential the
neuroprotective activity with low toxicity. The current study aimed to
find new herpotrichone neuroprotectants and investigate their
neuroprotective mechanism in vitro and in vivo. Experimental Approach:
Comprehensive separation methods were used to isolate new herpotrichone
analogues. The H2O2, RSL3, 6-OHDA-induced PC12 cells and LPS-induced
BV-2 cells were used to assess the potential neuroprotective effect of
compounds. UV-vis spectroscopy was used to determine the cell-free
antioxidant and iron-chelating capacity. Western blotting,
immunofluorescence, quantitative PCR, flow cytometry and enzyme-linked
immunosorbent assay (ELISA) were used to evaluate the activation of the
antioxidative elements and the regulation of the ferroptosis factors in
cell cultures and in zebrafish larvae. Key Results: Herpotrichone A
(He-A) and a new herpotrichone analogue with a new pentacyclic 6/6/6/6/3
skeleton exhibited significantly the neuroprotective effect in cell
cultures. He-A activated antioxidative elements and modulated SLC7A11
pathways. The decreased lipid ROS levels but increased GSH level showed
the anti-ferroptosis effect of He-A. The increased cell viability in
RSL3-induced PC12 cells and the improvement of locomotor in
6-OHDA-induced zebrafish larvae indicated that He-A possessed protective
ability against neuronal damage. Conclusion and Implications: This study
identifies a novel compound He-A that protects against neuronal damage
through activating Nrf2 pathway to upregulate antioxidative elements and
increasing the expressions of SLC7A11, FTL and FTH1 in vitro and in
vivo, which supports the development of He-A as a new neuroprotective
agent targeting ferroptosis.
Climate change and the biodiversity of alpine ponds: challenges and perspectives
Authors: Lamouille-Hébert Marie , Arthaud F. , Datry T.
Published: November 2023

1. Inland waters are among the most threatened biodiversity hotspots.
Ponds located in alpine areas are experiencing more rapid and dramatic
water temperature increases than any other biome. Despite their
prevalence, alpine ponds and their biodiversity responses to climate
change have been poorly explored, reflecting their small size and
difficult access. 2. To understand the effects of climate change on
alpine pond biodiversity, we performed a comprehensive literature review
for papers published since 1955. 3. Through analysis of their geographic
distribution, environmental features, and biodiversity values, we
identified which environmental factors related to climate change would
have direct or indirect effects on alpine pond biodiversity. We then
synthesized this information to produce a conceptual model of the
effects of climate change on alpine pond biodiversity. 4. Increased
water temperature, reduced hydroperiod, and loss of connectivity between
alpine ponds were the main drivers of biodiversity geographic
distribution, leading to predictable changes in spatial patterns of
biodiversity. 5. We identified three major research gaps that, if
addressed, can guide conservation and restoration strategies for alpine
ponds biodiversity in an uncertain future.
Infliximab-induced depression and Suicidal behaviour: a serious adverse event to consider
Authors: Thabet Maissa , Yahia Wissal Ben , Fathallah Neila , Guiga Ahmed , atig amira , ouni bouraoui , Ghannouchi Neirouz
Published: November 2023

Infliximab (INF) is a biological widely used in the treatment of various
auto-immune diseases including Behçet’s disease. INF and other
pro-inflammatory cytokines, has been retained in some cases as a factor
in the pathogenesis of various neuropsychiatric conditions. Herein we
present the case of an adult man with Behçet’s disease (BD) who
developed acute depression leading to suicide after the fourth infusion
of infliximab. The patient did not experience disabling depressive
syndrome, or suicidal thoughts before. He has never made a prior suicide
attempt. He denied any previous episodes of mania or psychosis or a
history of trauma. Our patient received a serotonin reuptake inhibitor
with a good response which allowed us to maintain infliximab therapy.