bluuebunny/crossref_metadata_2025 huggingface dataset:
Development Of Delphi-Based Learning Media in Electrical and Electronic Basic Students in SMKN 2 Serang
Authors:   Electrical Engineering Vocational Education Sultan Ageng Tirtayasa University, Indonesia, Irwanto Irwanto , Cahyono Bagus Dwi ,   Electrical Engineering Vocational Education Sultan Ageng Tirtayasa University, Indonesia, Wibowo Tubagus Umar Syarif Hadi ,   Department of History Education, Sultan Ageng Tirtayasa University, Indonesia, Nurmala Meilla Dwi ,   Guidance and counseling Sultan Ageng Tirtayasa University, Indonesia, Rizal Syamsul ,   Performing Arts Education Sultan Ageng Tirtayasa University, Indonesia
Published: June 2022

The development of science and technology has a direct impact on the preparation of a qualified workforce, including the preparation of workforce graduates of Vocational High Schools. One of the learning materials in Vocational High Schools is basic material on electricity and electronics. Introduction to the basic material of electricity and electronics will be very difficult if only with books. Therefore, this study aims to create an interesting and interactive learning media. This media uses the Delphi program. In the learning media, there are materials and exercises for basic electricity and electronics subject matter for passive components of RLC. The design of this learning media development follows the ADDIE stage (Analyze, Design, Development, Implementation, Evaluation). The validation of this learning media program includes validating the content and design of the media itself. Based on the results of data analysis, it was found that the learning media developed in this study had a very high validity value from the two aspects assessed. For the validity of the learning media subject matter, the results of validation by experts are 3.61 and validation by the teacher is 3.6 so that it is very relevant to the concepts to be taught using this media, while for the validity of media design by experts is 3.5 and by the teacher 3.62 so that the learning media This research can be declared fit for use to support learning in school.
DASHBOARD SUSTAINABLE DEVELOPMENT GOALS (SDGS) MENGGUNAKAN FRAMEWORK LARAVEL (STUDI KASUS KABUPATEN DAN KOTA PROVINSI LAMPUNG)
Authors: Tristiyanto Tristiyanto , Heningtyas Yunda , Aristoteles Aristoteles , Amran Muhammad Yusuf
Published: June 2022

On March 18, 1964, the Province of Lampung was established. In order to carry out efforts to develop Lampung Province, a development framework with a legal foundation and justice in each development process is required. The Sustainable Development Goals (SDGs) are a replacement for the Millennium Development Goals (MDGs), which were established as a result of an agreement amongst 189 leaders of UN member states with the primary goal of improving welfare and community development. As a result of this research, a dashboard was established to track the progress of the SDG indicators. The dashboard produced can analyze, manage, and display the progress of the SDG indicators in a way that all parties can simply read and understand. As a result, everyone at every level of society can understand and guarantee that development is carried out in accordance with the law in order to promote community welfare.
PENERAPAN METODE WATERFALL PADA PENGEMBANGAN SISTEM INFORMASI MONITORING PROSES BIMBINGAN SKRIPSI DI JURUSAN ILMU KOMPUTER UNIVERSITAS LAMPUNG
Authors: Septiawan Eko , Sakethi Dwi , Andrian Rico
Published: June 2022

The thesis is a compulsory task that must be completed by a student as a condition of graduation to obtain a bachelor's degree. The questionnaire of the thesis guidance process shows, there were students who experienced problems in the thesis guidance process. The thesis guidance process monitoring information system has previously been developed but is still in the prototype phase. This study aims to develop a system that can assist students in monitoring the status of thesis examination that is being carried out by supervisors as well as providing information about thesis guidance and the percentage of thesis guidance students passing. This research uses the waterfall method. The thesis guidance process monitoring information system will show announcements from supervisors, thesis progress status, and thesis draft checking information.
SISTEM INFORMASI PENJUALAN BUKU BEKAS DI KOTA BANDAR LAMPUNG BERBASIS WEB
Authors: Yusman Machudor , Hermanto Bambang , Rizaldi Ibnu
Published: June 2022

This study aims to create an information system that functions to sell used books in the city of Bandar Lampung. Currently the used book sales system still relies on media interaction with direct consumers and is still centered on a particular location. By creating a web-based used book sales information system in the city of Bandar Lampung, it can facilitate customer transactions in purchasing used books online. In this research the system design uses UML (Unifield Modeling Language), PHP (Hypertext Preprocessor) programming language, MYSOL as a database and using Windows as an operating system. Information systems are created by applying the Extreme Programming Method to determine the steps in making a system. System functional testing uses the Black Box Testing method in the functional test scenario. Accuracy testing uses 20 test cases that exist in the information system, then performed related to the system output with actual events. From the test results using 20 test cases, the results obtained are in accordance with the system output so that the test results are categorized as very good.
Kingdom Vision 2030 and the Women’s Empowerment in Saudi Arabia: An Empirical Investigation
Authors: ALHARBI MAI MOHAMMED H
Published: June 2022

Empowerment of women is the mirror of a society's civilization and development. It is vital and necessity for the success of the society’s comprehensive development. This study aims to explore the role played by the "Kingdom's vision 2030" in empowering Saudi women. The study applied a questionnaire consisting of five axes that express the awareness of empowering Saudi women according to the “Vision 2030”. A total of 152 responses were received in two months. The study used both the descriptive and analytical approaches to analyse the collected data. The results showed that there are statistically significant differences in the awareness of empowering Saudi women in the view of Vision 2030 based on the respondents ages, nature of their profession and level of education. The study recommended that more opportunity for women in terms of education and property ownership can encourage women to put more efforts towards the development of the Kingdom.
Kajian Analisis Etude Biola: “Franz Wohlfahrt Easiest Elementary Method for Beginners Op.38”
Authors: Ridhwan Urfan Saniylabdhawega , Sukmayadi Yudi
Published: June 2022

Etude merupakan sebuah hal yang harus dipelajari dan bersifat fundamental dalam pembelajaran instrumen musik khususnya pembelajaran instrumen biola. “Franz Wohlfahrt Easiest Elementary Method for Beginners Op.38” ialah salah satu dari sekian banyak etude yang memiliki berisikan berbagai teknik permainan biola dan uniknya dimainkan secara duet. Tentunya akan memberikan nilai lebih dari permainan secara duet tersebut dalam pembelajaran antara guru dan siswa. Tujuan dari artikel ini ialah mengkaji teknik permainan biola dan kompetensi dasar yang terdapat pada etude “Franz Wohlfahrt Easiest Elementary Method for Beginners Op.38”. Metode yang digunakan ialah metode deskriptif analitis yaitu memberikan sebuah gambaran secara deskripsi terhadap objek yang dikaji oleh peneliti melalui data yang dikumpulkan dan sudah dianalisis. Etude ini memberikan sebuah pembelajaran biola dengan permainan duet didalamnya sehingga dapat memberikan berbagai kebermanfaatan secara teknik permainan biola maupun manfaat kontekstual.
Penyusunan Modul Kewirausahaan dan Ekonomi Kreatif Berfokus Profil Lulusan Sebagai Upaya Pemberdayaan Mahasiswa Pendidikan Musik
Authors: Sakti Reza Ginandha
Published: June 2022

Kewirausahaan pada tahun 2021 menjadi mata kuliah yang wajib diselenggarakan oleh seluruh program studi di lingkungan Institut Seni Indonesia Yogyakarta untuk membekali dan memberdayakan mahasiswa setelah menyelesaikan Pendidikan. Mata kuliah kewirausahaan telah dilaksanakan sejak tahun 2019 di dengan nama Entrepreneurship di Program Studi Pendidikan Musik Fakultas Seni Pertunjukan ISI Yogyakarta. Profil lulusan di Program Studi Pendidikan Musik yang mencakup pengelola seni, konsultan, serta pendidik atau instruktur musik memiliki kaitan erat dengan ekonomi kreatif. Permasalahan yang terjadi adalah mahasiswa sangat minim pengetahuan tentang kewirausahaan dan industri kreatif bidang musik sesuai dengan profil lulusan. Untuk mengatasi hal tersebut, dirancanglah sebuah modul mata kuliah kewirausahaan berfokus ekonomi keatif yang sesuai dengan profil lulusan. Secara garis besar, modul berisi pemahaman tentang kewirausahaan, profil pengusaha, dan jenis kegiatan ekonomi industri kreatif bidang musik. Instrumen yang digunakan untuk mengumpulkan data dalam penelitian ini adalah lembar validitas dan lembar pertanyaan. Validator berasal dari kalangan praktisi, akademisi, dan ahli komunikasi. Berdasarkan hasil analisis data modul memiliki validasi tinggi dengan skor 93 yang berarti dapat digunakan tanpa revisi. Modul layak digunakan dan efektif untuk meningkatkan pengetahuan dan motivasi mahasiswa dalam bidang kewirausahaan dan industri kreatif bidang musik.
Bentuk dan Struktur Musik Rodat di Kabupaten Empat Lawang
Authors: Sandika Dera , Firmansyah Feri , Putra Rio Eka
Published: June 2022

Artikel ini merupakan hasil penelitian yang bertujuan mendeskripsikan salah satu bentuk dan struktur musik daerah, yaitu musik rodat di Kabupaten Empat Lawang, sebagai bentuk inventarisasi musik daerah yang ada di Nusantara. Penelitian didasari fenomena musik rodat yang disajikan dengan nyanyian dan tarian, diiringi dengan tabuhan terbangan dan jidur, dan terdapat leluconnya. Selanjutnya sajian tersebut disuguhkan dalam sebuah arak-arakan, untuk ditonton masyarakat sekitar desa. Untuk mendeskripsikan bentuk dan struktur Musik Rodat, pengumpulan data dilakukan dengan observasi, wawancara, dan dokumentasi. Selanjutnya data akan disajikan secara deskriptif, melalui hasil dari analisis bentuk dan struktur musik. Hasil penelitian didapatkan bahwa musik rodat di Kabupaten Empat Lawang merupakan ansambel musik yang terdiri dari unsur pokok yaitu vokal, lagu dan syair, sajian instrumen, dan gerak tari. Lagu pada musik rodat ini memiliki 3 bentuk dan stuktur yang umum disajikan yaitu pola A-B-B, A-B-B-A, dan A-B. Setiap rangkaian penyajian musik rodat ditampilkan tarian dan diselingi dengan lulucon.
Transkripsi Musikal Pertunjukan Rapai Pasee Di Aceh Utara
Authors: Karina Angga Eka , Widyastutieningrum Sri Rochana , Hirza Herna
Published: June 2022

Pertunjukan Rapai Pasee adalah musik perkusi yang menampilkan pertunjukan adu pola ritme oleh dua grup musik yang tampil bersamaan dalam satu panggung. Pola ritme yang dimainkan disebut dengan Lagu. Masing-masing Lagu memiliki susunan pola ritme yang berbeda satu sama lainnya. Hal ini menarik untuk dideskripsikan dalam bentuk transkripsi musikal. Teori merujuk pada Nettl dan Seeger (Chase & Nettl, 1965), (Charles Seeger, 2012) mengatakan bahwa transkripsi adalah proses menotasikan bunyi, mengalihkan bunyi menjadi simbol visual, atau kegiatan memvisualisasikan bunyi musik ke dalam bentuk notasi dengan cara menuliskannya ke atas kertas. Data penelitian didapatkan dengan mengamati kesenian Rapai Pasee yang dilakukan oleh Grup Putra Pasee dan Grup Raja Buah sebagai kelompok dengan persentase paling sering tampil dan juara pada kompetisi yang dilakukan di Aceh Utara. Data-data penelitian didapatkan melalui pengamatan, rekaman musik, diperkuat dengan wawancara dengan masyarakat yang terlibat dalam kesenian  Rapai Pasee. Hasil yang diperoleh menjelaskan bahwa transkrispi musikal secara deskriptif terdiri dari Lagu Sa, Lagu Dua, Lagu Lhee, Lagu Limoeng, Lagu Tujoh, Lagu Sikureung dan Lagu Duablah secara detail menurut apa yang ditangkap oleh indera pendengaran peneliti dengan maksud untuk menyampaikan ciri-ciri dan detail-detail komposisi musik Rapai Pasee.
Aransemen Sholawat Syi’ir Tanpo Waton: Sebuah Proses Kreatif
Authors: Satria Eki
Published: June 2022

Penulisan artikel ini berisikan dua pembahasan, yang pertama adalah deskripsi mengenai konsep penyusunan aransemen Sholawat Syi’ir Tanpo Waton, dan yang kedua adalah proses proses penyusunannya. Metode yang digunakan adalah kualitatif dengan pendekatan artistik berupa practice based research. Teknik pengumpulan data dilakukan dengan cara studi pustaka, observasi, wawancara, proses aransemen. Teknik analisis data menggunakan reduksi data, display data dan verifikasi. Hasil pembahasan berupa tahapan-tahapan dari dua proses pokok dalam aransemen yaitu: 1) Konsep aransmen Syi’ir Tanpo Waton yang berisikan tahapan  penetapan bentuk musik, pemilihan bait syair, instrumentasi, konsep melodi dan konsep harmoni; 2) Proses penyusunan aransemen Sholawat Syi’ir Tanpo Waton yang berisikan tahapan dalam penyusunan Intro/bagian A, transisi, bagian B, episode, bagian B’ dan codetta.
Manajemen Pertunjukan Seni Tradisional Berbasis Keragaman Budaya dan Kearifan Lokal Sumatera Utara
Authors: Sinaga Osberth
Published: June 2022

Studi ini mengkaji manajemen pertunjukan seni tradisional berbasis keragaman dan kearipan lokal Sumatera Utara. Berbagai perhelatan pertunjukan seni tradisional maupun pameran seni tradisional Sumatera Utara dapat menjadi daya tarik tersendiri bagi perkembangan industri pariwisata maupun pembangunan kebudayaan, namun demikian berbagai jenis keragaman seni pertunjukan ini masih telihat apa adanya saja dan tentu saja masih kalah bersaing dengan model-model seni pertunjukan populer dengan segala kecanggihan dan model manajemen pertunjukan yang lebih baik. Metode yang di gunakan dalam penelitian ini adalah penelitian lapangan dengan metode deskripsi kualitatif yaitu menggambarkan atau mengamati fakta - fakta yang sedang berlangsung. Tekhnik pengumpulan data dan penelitian ini adalah observasi dan wawancara. Tekhnik pengolahan dan analisa data di gunakan metode deskripsi kualitatif yaitu, menguraikan bagaimana proses manajemen yang diterapkan. Dalam studi ini ditemukan hasil kajian sebagai berikut : Manajemen pertunjukan seni memiliki peran dan kedudukan yang penting dalam kaitannya dengan target pencapaiannya secara optimal. Ada empat unsur manajemen pertunjukan seni yang sangat penting, yakni: 1) Unsur perencanaan yang menetapkan kebutuhan yang bersifat fital untuk memenuhi ketercapaian tujuan ideal. 2) Unsur pengorganisasian yakni dengan menempatkan SDM yang berkualitas. 3) Unsur pelaksanaan yakni telah ditetapkan aktivitas dalam mencapai tujuan pertunjukan seni. 4) Unsur Controling atau evaluasi untuk menentukan standar atau tolak ukur keberhasilan manajemen petunjukan seni baik evaluasi secara sistem ataupun produk hasil pertunjukan seni.
El cartel del ICAIC (Instituto Cubano del Arte e Industria Cinematográficos) como construcción de la imagen de la Revolución Cubana
Authors: Bartolomé Ángel , Martín Gómez Sonia , Lago Ávila María Jesús
Published: June 2022

El cartel de cine del ICAIC (Instituto Cubano del Arte e Industria Cinematográficos), como medio de comunicación visual, rompió radicalmente con los viejos cánones y se utilizó para construir la imaginería de la Revolución Cubana. Con grandes influencias de las escuelas del cartel polaco, checo, japonés y estadounidense se convirtió en un cartel reconocible por su colorido, forma de impresión y por establecer una gráfica que sirvió no solo para anunciar las películas sino para decorar e impregnar de colorido Cuba.
La Revolución cubana impulsó nuevos códigos en la realización y la percepción tanto de carteles de cine, políticos, así como de campañas económicas y de educación. Las necesidades que generó este proceso complejo trajeron consigo el deber de explicar, exhortar, convencer y provocar cambios en todo el país, lo que convirtió al diseño gráfico en una herramienta fundamental para conseguir de manera rápida y sencilla los propósitos de la Revolución.
El caso del cartel del ICAIC representa un caso peculiar, significativo y podríamos decir que único en la industria cinematográfica.
El discurso de las litografías que acompañaron a las novelas históricas de Mateos y Riva Palacio durante los primeros años de la República Restaurada (1868-1870)
Authors: Milán López Juan Alfonso
Published: June 2022

En el artículo se analiza el discurso de las litografías que ilustraron a las novelas históricas que aparecieron en los primeros años de la República Restaurada (1867-1870). Estos ejercicios visuales pretendieron afianzar la identidad nacional y mantener viva la llama del patriotismo liberal. Se intenta demostrar que dichas imágenes no sirvieron como un mero elemento ilustrativo, sino que mantienen un mensaje propio, que fueron referentes pedagógicos de las élites políticas y letradas para educar a la población, y que fueron útiles para señalar los vicios y abusos cometidos durante la época colonial, laudar a los héroes del movimiento por la independencia, y fomentar la memoria colectiva sobre los hechos recién vividos: la Intervención Francesa y el Segundo Imperio.
El ejército de Estrada. Disección de una rebelión frustrada en la frontera norte, 1926-1927
Authors: Grijalva Dávila Miguel Ángel
Published: June 2022

Esta es la historia del ejército de Enrique Estrada, un cuerpo de exiliados rebeldes con base en California, quienes pretendieron cruzar a México y derrocar a la presidencia de Plutarco Elías Calles en agosto de 1926. Fueron detenidos por las autoridades estadunidenses cuando se dirigían a cruzar la frontera, arrestados y enjuiciados. El objetivo, a grandes rasgos, es conocer las circunstancias en las que los exiliados de la revolución organizaban incursiones armadas desde E.U., cómo eran las relaciones gubernamentales para evitar esas incursiones y cómo se componía el grupo de Estrada. Para este objetivo, se dio prioridad a la documentación depositada en los National Archives of Record Administration (NARA), en el estado de Maryland, donde hay documentos sobre la investigación y juicio del grupo armado sobre el que nos enfocamos. Cabe señalar, es documentación poco explorada por la historiografía mexicana. Los aportes más significativos es el uso de dichas fuentes, así como la desvelación de los obstáculos, retos y complicaciones que tenían los exiliados al planear una rebelión desde E.U., algo que se repitió en muchos casos durante la revolución, pero se ha investigado poco. Por último, el texto propone que las relaciones entre agencias de ambos gobiernos, de seguridad e inteligencia en este caso, tenían una relación autónoma e independiente de la relación entre cancillerías.
Early use of corticosteroids and sarilumab in SARS-Cov-2 pneumonia.
Authors:   Clinical Pharmacology Department. Hospital Universitario Puerta de Hierro-Majadahonda. Instituto de Investigación Sanitaria Segovia de Arana, Caballero-Bermejo AF , Sancho-López A , Avendaño-Solá C , Ruiz-Antorán B ,   Clinical Pharmacology Department. Hospital Universitario Puerta de Hierro-Majadahonda. Instituto de Investigación Sanitaria Segovia de Arana, Ussetti-Gil P ,   Pneumology Department. Hospital Universitario Puerta de Hierro-Majadahonda. Instituto de Investigación Sanitaria Segovia de Arana, Fernández-Cruz A ,   Infectious Diseases Unit. Internal Medicine Department. Hospital Universitario Puerta de Hierro-Majadahonda. Instituto de Investigación Sanitaria Segovia de Arana
Published: June 2022

The cytokine storm underlying the inflammatory phase of COVID19 has been suggested since the beginning of the pandemic as a target for treatment of the disease. The identification of the presence of elevated IL6 levels in patients with severe SARS-CoV-2 infection led to the hypothesis that the use of already marketed drugs whose mechanism of action is the inhibition of IL6 could result in clinical benefit for these patients. We hypothesised that the use of glucocorticoid-associated sarilumab in early stages of the proinflammatory phase of COVID19 could prevent progression to respiratory distress syndrome and death. Hospitalised patients with SARS-CoV2 pneumonia, treated with nasal cannula and with analytical parameters of inflammation, were randomised (1:1 ratio) to receive sarilumab + standard therapy (sarilumab group) or standard therapy (control group). In all cases, standard therapy included glucocorticoid treatment for at least 3 days at a dose equivalent to methylprednisolone mg/kg/day. The primary endpoint was the percentage of patients who progressed to severe respiratory failure (defined as a BRESCIA-COVID score ≥3), intensive care unit (ICU) admission or death at any time up to day 15. A total of 201 patients were included, of whom 99 were randomised to the sarilumab group and 102 to the control group. The percentage of patients who progressed to severe respiratory failure (BRESCIA≥3), ICU admission or death at any time up to day 15 was 16.6% in the sarilumab group and 15.69% in the control group (RR 1.03; 95% CI, 0.48 to 2.20). No differences in the safety profile between the two groups were detected. Mortality at day 28 was 2.02% in the sarilumab group vs. 1.96% in the control group (RR 1.03; 95% CI 0.14 - 7.46). In conclusion, an early intervention with sarilumab and glucocorticoids did not demonstrate clinical benefit in our study population compared to standard therapy.
Dmrt5 beyond the cortex: early role in the sexual differentiation of the mouse limbic system.
Authors:   Centro de Biología Molecular Severo Ochoa (CSIC-UAM), Program of Tissue and Organ Homeostasis, Madrid, Spain., Casado-Navarro Rafael , Torrillas-de la Cal Rodrigo , Serrano-Saiz Esther ,   Centro de Biología Molecular Severo Ochoa (CSIC-UAM), Program of Tissue and Organ Homeostasis, Madrid, Spain., Macho Rendón Javier , Martínez-Morales Juan Ramón ,   Centro Andaluz de Biología del Desarrollo-CABD (CSIC/UPO/JA), 41013, Seville, Spain.
Published: June 2022

The mammalian limbic system is sexually dimorphic and underlies sex-specific innate behaviors such as mating, maternal care, and aggression. However, the genetic programs involved in the sexual differentiation of the limbic system are poorly understood. Dmrt transcription factors have emerged as conserved regulators of sex-specific traits across animal kingdom. They have been studied mostly in invertebrates, where they play an important role in nervous system sexual differentiation. In mammals, Dmrt genes have been predominantly studied in the gonads, however, Dmrt5, controls cortex development in humans and mice. In fact, mutations in DMRTA2 (Dmrt5) lead to a recessive human condition characterized by microcephaly and lissencephaly. Surprisingly, there are no studies beyond the cortex nor comparing males and females. In this work we use Dmrt5 null mutant mice, RNAseq and histological techniques to study Dmrt5 function in the developing mammalian nervous system beyond the cortex and comparing males and females. It is plausible that genetic factors involved in brain sexual differentiation, like Dmrt, may represent also etiologic causes for mental disorders, explaining the observed male-female sexual bias. In this study we showed that Dmrt5 is broadly expressed in the mouse nervous system, including the vomeronasal organ, olfactory tubercle, or ventral tegmental area (all key nodes in the control of innate behaviors). Furthermore, we showed that Dmrt5 is necessary for the correct specification of the main olfactory epithelium, the olfactory bulb, and several hypothalamic nuclei. Additionally, we found a novel function for Dmrt5 as a suppressor of sex differences in gene expression in the posterior hypothalamic area and midbrain. In this region, Dmrt5 could be specifying and maintaining a neuronal subpopulation or a group of neurons only in males. Taken together, Dmrt5 comes out as a crucial transcription factor for the accurate differentiation of limbic regions, integrating sex information. By studying the genetic factors involved in sexual differentiation of the nervous system, we might find potential factors to either afford protection or generate vulnerability in one sex versus the other for sex-biased mental disorders.
A unique F-actin and junctional organization that maintains the corneal endothelial barrier
Authors:   Centro de Biología Molecular Severo Ochoa-CSIC, UAM, Madrid, Madrid, Spain, Cerro-Tello G , Benito-Martínez S , Cacho-Navas C , Barroso S , de Rivas-Hidalgo G , Millán J ,   Centro de Biología Molecular Severo Ochoa-CSIC, UAM, Madrid, Madrid, Spain
Published: June 2022

Introduction: The corneal endothelium is responsible for the correct hydration of the corneal stroma and for an adequate transport through this tissue. Corneal endothelial layer has a particular organization to maintain its curved shape and function. The corneal endothelium has low proliferative capacity and form a monolayer that is subjected to an even mechanical tension coming from the positive pressure of the aqueous humor. Preserving their barrier function under suboptimal conditions, such as corneal pathologies, age and transplantation, is essential for maintaining corneal transparency. Material and methods: We have investigated the structure and the proteins in charge of maintaining corneal endothelial barrier function by confocal microscopy and time lapse spinning disk microscopy in murine corneas ex vivo, and hepatic organoids. Results: We have characterized a novel filamentous actin network that organizes into radial structures arising from the center of the cell under the nucleus towards cell-cell junctions. This structure is also observed in spherical epithelial organoids whose cells are also exposed to positive luminal pressure. Due to the simplicity of the model, it can be easily implemented in any clinic which leads to increasing ADR and preventing CRC, but requires validation in large multicenter trials.
In vivo nanotracer for the detection of brain thrombi in an AD mouse model.
Authors:   Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernandez Almagro 3, Madrid, Spain., Fuster Valentín ,   Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, New York, Cerón Carlos , Casquero-Veiga Marta , Fernandez-Nueda Irene , Moro María Ángeles ,   Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernandez Almagro 3, Madrid, Spain., Fernandez-Barahona Irene , Herranz Fernando ,   Instituto de Química Medica (IQM), Juan de la Cierva 3, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain,   CIBER de Enfermedades Respiratorias (CIBERES), Monforte de Lemos 3-5, Madrid, Spain, Cortes-Canteli Marta ,   Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Melchor Fernandez Almagro 3, Madrid, Spai,   CIBER de Enfermedades Neurodegenerativas (CIBERNED), Monforte de Lemos 3-5, Madrid, Spain
Published: June 2022

Background: Alzheimer’s disease (AD) is the most common cause of dementia. It is a multifactorial degenerative disease pathologically characterized by intracellular neurofibrillary tangles and extracellular deposition of amyloid. An early hemostatic dysregulation is also present and contributes to an increment in clot formation, leading to hypoperfusion, blood brain barrier disruption and neuronal loss. The detection of this prothrombotic state is of the upmost importance in diagnostic approaches to identify AD patients who would benefit from anticoagulation. Method: The aim of this project is to use an in vivo nanotracer for the detection of brain thrombi in an AD mouse model by fast pre-targeted positron emission tomography (PET) imaging. For that purpose, AD animals and their wild-type littermates were intravenously injected with the antiplatelet antibody against CD41 conjugated with transcyclooctene (TCO-antiCD41). Twenty-four hours later, [68Ga]core-doped iron oxide nanoparticles (NP) functionalized with tetrazine (TZ) were intravenously administered. TCO and TZ produce a rapid in vivo reaction by means of bioorthogonal chemistry, allowing to non-invasively evaluate platelets’ levels by PET. Two hours after [68Ga]NP-TZ injection, a static PET study of each mouse was acquired with a scanner for small animals (nanoScan® PET/CT, Mediso, USA). Finally, biodistribution assays of different organs after the PET study were performed. All PET images were analyzed by regions of interest and voxel-wise analyses. Conclusions: Our results provide a neuroimaging strategy to diagnose the prothrombotic state towards the personalization of anticoagulation treatment in AD patients.
PENDIDIKAN ISLAM DI ZAMAN KEMAJUAN DALAM TINJAUAN SEJARAH PERADABAN ISLAM
Authors: Abdul Rasak Muhammad Sarib
Published: June 2022

Islamic education is always changing from time to time, one of the important things to analyze is Islamic education in the period of progress in the era of the Abbasid dynasty. History records that the journey of Islamic education had progressed so rapidly, far behind Western education. However, later it experienced a setback and was inversely proportional to Western education which continued to soar far ahead of leaving Islamic education until now. Therefore, it is important to reflect on the glorious history of Islamic education or what is called the era of progress in Islamic education. Studying and understanding things that promote Islamic education in the age of progress, as an effort to build Islamic education in the future. Thus, based on the explanation that has been described, the formulation of the problem to be solved in this study is related to the description of Islamic education in the era of progress, in this study, namely library research, namely the type of research conducted by reading books or magazines and other data sources to collect data. data from various literature, both libraries and in other places. History records Islamic education in the Abbasid era as a period of progress and glory of Islamic education. The caliph as the holder of the power is a figure who is so strong and loves science very much. The seven caliphs who were known to love the development of science were al-Mahdi, al-Hadi, Harun al-Rashid, al-Ma'mun, al-Mu'tashim, al-Wasiq, and al-Mutawakkil. The rapid development of science was centered in Baghdad and lasted for approximately five centuries (750 AD - 1258 AD). Throughout the Abbasid Caliphate, many well-known educational institutions have been built, one of which is Baitul Hikmah. During the Abbasid era, the Nizamiyah Madrasah educational institution appeared for the first time and was the forerunner to the development of Madrasah in today's modern era.
PENDIDIKAN KARAKTER DALAM PROSES PEMBELAJARAN
Authors: Pakai Asra J.A
Published: June 2022

This paper intends to describe character education in relation to the learning process. This research uses the library research method. Data collection in this study was carried out using a citation technique, namely quoting from various references related to the concept of character education and its relationship to the learning process. Data analysis by the author is carried out after the data is collected, the author analyzes in a methodical order and describes it using inductive-deductive reasoning. The curriculum contains learning materials or methods used by a teacher to students achieve the expected educational goals, then this curriculum produces a syllabus or lesson plan, or lesson plan. With the agreed learning plan, a teacher must be able to practice or implement character education in the learning process. One proof of the success of a teacher in implementing character education to students is that a student can connect the material obtained in class with real life
Comparison of Changes in Electricity Consumption Distribution in Day and Night Scale Caused by Nord Pool Spot Prices Volatility
Authors: Lill Heiki , Pihlap Heino
Published: June 2022

Under free market conditions, there should be a correlation between price and demand. In the electricity market, it is not possible to shift all consumption to hours that are more favourable. Therefore, free market rules do not fully apply to the electricity exchange market. Household consumers have a better ability to shift their energy consumption. At the same time, a large number of household consumers have fixed-price contracts and are therefore not affected by the sharp price changes, so it can be said that they do not actively participate in the stock market. They do not need to shift their electricity consumption. High-consumption industrial companies have very low possibilities at all to react to the stock market changes. The aim of this study is to find out how much electricity consumption has been able to shift in a situation where electricity prices in Estonian were extremely high and volatile. Electricity prices are usually lower at night-time, so it can be assumed that consumption will be shifted to night-time if possible. Examining the change in the distribution of night- and daytime electrical consumption over the years, it is possible to analyse the effect of energy prices on consumer behaviour during periods of high volatility.
PEMANFAATAN MEDIA DIGITAL DALAM PENGELOLAAN KESEHATAN MENTAL REMAJA DI ERA PANDEMI
Authors: Janitra P. A. , Prihandini P. , Aristi N.
Published: June 2022

Data menunjukkan bahwa penggunaan media digital semakin meningkat, terutama semenjak pandemi Covid-19, khususnya di kalangan remaja. Selain itu, berbagai studi juga telah memperlihatkan keterkaitan antara penggunaan media digital dan kesehatan mental remaja. Dengan demikian, kemampuan memanfaatkan media digital pun berperan penting dalam mengelola kesehatan mental remaja. Kegiatan pengabdian ini bertujuan untuk meningkatkan literasi remaja Indonesia mengenai cara penggunaan media sosial yang baik bagi kesehatan mental serta mengedukasi remaja terkait dampak penggunaan media digital bagi kesehatan mental. Adapun metode yang digunakan dalam pelaksanaan kegiatan pengabdian ini yaitu dengan penyuluhan (seminar), diskusi interaktif secara virtual, dan kuis yang melibatkan peserta dari kalangan remaja, terutama siswa-siswi sekolah menengah atas (SMA) dan mahasiswa. Hasil dari kegiatan ini menunjukkan bahwa remaja yang menjadi peserta menggunakan media digital, khususnya media sosial, secara aktif dan peserta dapat memahami materi yang disampaikan terkait media digital dan kesehatan mental. Hal ini dapat diidentifikasi melalui keterlibatan aktif peserta dalam diskusi dan penilaian atas jawaban peserta dalam kuis yang relevan dengan materi.
DISAIN FASILITAS PENDUKUNG KAYEHAN DESA ALAS JERINGO DI DESA PEDAWA
Authors: Prajnawrdhi T. A. , Paramadhyaksa I. N. W. , Mahastuti N. M. M. , Satria M. W.
Published: June 2022

Kayehan Desa in Pedawa Village is a water source and public facilities that are used by all levels of Pedawa society. Kayehan desa located in a water source area in the middle of the forest, the condition of these public facilities are still not feasible and difficult to reach during the rainy season.  One of the kayehan desa named Kayehan Desa Alas Jeringo has great potential to be developed under the community service activities in the PUU scheme in 2020. This paper will discuss the design of the supporting facilities needed by the village of Alas Jeringo so that it can function more optimally both in the dry season and in the rainy season. Qualitative methods that involve field observations, interviews and discussions are used to generate a suitable design concept that combines the designer's ideas and is able to accommodate the aspirations of the local community. SWOT analysis applied for this study. The results show that the appropriate design for the Kayehan Desa supporting facilities in Alas Jeringo uses the concept of tropical architecture and sustainable architectural design so that these facilities are able to provide good sustainable functions and can be used by local communities and visitors who come to visit in the long term. Moreover, with the concept of tropical and sustainable architecture, the design of supporting facilities does not damage the surrounding environment.
PERAN MAHASISWA DALAM MITIGASI COVID-19 MELALUI PROGRAM KULIAH KERJA NYATA SECARA DARING DAN LURING
Authors: Valentin A.P. , Sukarsa I.K.G.
Published: June 2022

The Udayana University Community Service Program was carried out differently from the previous year. The Covid-19 pandemic has made KKN students appointed as agents of health protocol for the community. For this reason, students from Banyuwangi form the Udayana University Community Service Community Service Volunteer Team. The Udayana University Community Service Community Service Volunteer Team had the opportunity to carry out activities in Sukonatar Village, Srono District, Kab. Banyuwangi with the theme "Sukonatar Village Responds to Covid-19 Mitigation". This time the KKN was carried out online and in combination, for one month and one week the students compiled a schedule tailored to each work program in three fields, namely Public Health and Kesling, Education, and Social and Economy. Based on the grouping of the three areas that have been mentioned, it is intended to overcome the problems that arise by providing solutions with solution ideas, so that the community can survive even during a pandemic. In addition, it is also hoped that with a form of contribution of thoughts and energy from students regarding the prevention and handling of Covid-19 it can help the community a little, especially in Sukonatar Village.
PENINGKATAN KEMAMPUAN MENULIS SISWA PAKET B DAN C MELALUI PELATIHAN TEKNIK PENULISAN ILMIAH
Authors: Sumarjaya I. W. , Joni M. , Sibarani J. , Gautama I. P. W.
Published: June 2022

As a nonformal education institution for students that dropped-out of schools, pusat kegiatan belajar masyarakat (PKBM) plays important role in promoting the spirit of lifelong learning and community learning. One of the fundamental components of education, either formal or nonformal, is writing. The ability to write, especially scientific writing, is not an inborn talent but acquired. Results of interview conducted in early February 2019 concluded the followings. First, students are not capable of doing scientific writing correctly. This can be seen from their inability in creating cohesive and coherence sentences. Second, the students seem to lack confidence when participating in writing competition held regularly by Kemdikbud. Finally, the workplace often requires employees to make correspondence and written reports. One way to improve students’ ability to write scientifically is through basic scientific writing workshop. This community service started by giving questionnaires to students which consists of an informal writing about themselves and a scientific writing about social phenomenon. The next step is delivering workshop, giving posttest, and doing workshop evaluation. Based on our evaluation we conclude that the workshop can improve students’ ability to write scientifically.
PENCEGAHAN PENULARAN PENYAKIT FLU BURUNG OLEH UNGGAS MELALUI PENYULUHAN DAN VAKSINASI AYAM BURAS NYAMBU
Authors: Kencana G.A.Y. , Suartha I.N. , Apsari I.A.P. , Kendran A. A. S. , Suardana I. B. K.
Published: June 2022

The main host of Avian Influenza is poultry, including domestic chickens because domestic chickens are kept without cages (released). Extraordinary Avian Influenza has occurred in Indonesia, including in Tabanan Regency, Bali in 2003-2006. The case of human deaths due to Bird Flu had occurred in Banjar Batugaing Desa Beraban in Kediri District. Nyambu Village is located in Kediri Subdistrict, Tabanan Regency, many residents raise domestic poultry. The total population of free-range chickens in Kediri District is 30,171 in 2016. Considering the potential of Nyambu Village whose residents mostly raise free-range chicken by means of release, it is very vulnerable to the spread of Avian Influenza in the Village. The purpose of community service in Nyambu Village is to prevent the onset of Avian Influenza. The main target of community service in Nyambu Village is the villagers who maintain free-range chicken. Community service activities have been carried out on July 28, 2018 at the Nyambu Village Office followed by the Village apparatus and the local community. They were given counseling then continued with vaccination on their domesticated chickens from one house to another, it’s used AI inactive vaccine by intramuscullare injected. As many as 230 domestic chickens of various ages have been successfully vaccinated.
PEMANFAATAN BIOGAS UNTUK PEMBANGKIT LISTRIK SKALA RUMAH TANGGA
Authors: Nindhia T.G.T. , Surata I.W. , Nindhia T.S. , Swastika I.D.N.P.
Published: June 2022

Cemadik Village, Tampaksiring District in Gianyar Regency, Bali is an agricultural village with most of its inhabitants as farmers and ranchers. Livestock, especially cattle and pigs are widely available in this area and very potential to be developed as a source of energy reserves especially biogas obtained from the processing of farm waste through anaerobic digester. Biogas is commonly used for cooking but the use of further biogas for biogas power plants needs to be developed and disseminated. This is due to the decreasing availability of conventional energy which causes the price of electricity continues to increase. This dedication aims to build a pilot biogas power plant project to introduce and disseminate affordable and cost-effective technology of household-scale biogas power plant in Cemadik Village, Tampaksiring District, Gianyar, Bali. Furthermore, this activity succeeds to create a biogas power plant with a capacity of 1000 watts with biogas fuel and has been installed with a well equipped house generator.
DETEKSI DINI STATUS KESEHATAN, PENGETAHUAN, SIKAP DAN PERILAKU MASYARAKAT TERKAIT COVID-19
Authors: Suartha I.N. , Suarsana I.N. , Idayati I.G.A.A. , Gayatri I.A.P. , Oka P.I.S.S. , Pebyanthi P.K. , Dewi I.A.M.L.
Published: June 2022

The coronavirus (Covid-19) outbreak, which has infected almost all countries in the world, has been declared a pandemic. In Bali, It was spread due to local transmission. Prevention of transmission is influenced by attitudes, knowledge, and community awareness. This study aims to determine the early health status, knowledge, and attitudes of Gulingan Village community regarding the Covid-19 pandemic outbreak. The data were collected through a questionnaire distributed to six sub-villages, with 20 questionnaires every sub-village. The data collected in the form of respondent demographics, public health conditions related to Covid-19, knowledge, attitudes, and behavior in implementing health protocols. The data were collected from July to August 2020. The results of surveillance activities were 94.4% had low risk, while 0.8% had moderate risk. The level of knowledge of the Gulingan village community about Covid-19 was classified as good at 69.9%, while less knowledgeable was 30.1%. In response to the Covid-19 pandemic, it was found that 65.9% had obeyed the rules and implemented health protocols in their daily activities. On the other side, 34.1% was still classified as poor. The conclusions of this activity are: The health status of the Gulingan Village community regarding Covid-19 has a low risk, with a good level of knowledge and obedience to health protocols.

Keywords: Covid-19, knowledge, attitude, surveillance, early detection
PENERAPAN GERAKAN SERIBU BIOPORI (GASEBO) DALAM MENGATASI PROBLEMATIKA SAMPAH ORGANIK
Authors: Yuliani C. , Kusuma M.R. , Pastika I.P. , Wisudawati N.N.S.
Published: June 2022

Penelitian ini bertujuan untuk memecahkan masalah terkait sampah di Desa Penebel dan menjadikan Desa Penebel sebagai Desa Wisata Berbasis Lingkungan. Lingkup dari penelitian ini berupa pengertian biopori, keunggulan dan manfaat pembuatan lubang biopori, cara membuat biopori, dan rencana berkelanjutan biopori di Desa Penebel. Adapun metode yang digunakan yaitu dengan observasi langsung dan mempraktekkan cara pembuatan lubang biopori. Hasil dari pelaksanaan biopori  diharapkan dapat mengatasi problematika sampah dan menunjukkan bahwa Desa Penebel yang dijadikan sebagai tempat penelitian sekaligus sebagai pelopor penerapan biopori, yang nantinya jika terus diterapkan maka akan menghasilkan manfaat yang lebih baik untuk Desa Penebel. Dalam merealisasikan pemberdayaan masyarakat berkelanjutan, sesuai visi yang diinginkan agar Desa Penebel bebas dari sampah, maka rencana berkelanjutan yang dicanangkan yaitu, setiap masyarakat dapat memilah sampah organik dan non organik. Dimana sampah organik dapat dimasukan kedalam lubang biopori dan hasilnya setelah terurai maka dapat dimanfaatkan sebagai pupuk kompos. Untuk hasil yang maksimal dalam pengurangan limbah rumah tangga disetiap rumah diharapkan memiliki minimal 10 lubang biopori.
DISEMINASI TEKNOLOGI FERMENTASI URIN MENGGUNAKAN MIKROORGANISME LOKAL (MoL) SEBAGAI DEKOMPOSER ALAMI
Authors: Said M. I. , Amran Amran , Yuliati F. N.
Published: June 2022

The increasing use of chemical fertilizers, especially in rural areas, has a very large effect on agricultural production. Utilization of livestock waste (urine) as raw material for liquid organic fertilizer (LOF) has the potential to replace the use of chemical fertilizers. The basic problem that occurs is that the availability of microorganisms in the form of commercial decomposers for the LOF production process is becoming increasingly expensive and difficult to obtain. The purpose of this activity is to increase the knowledge capacity of farmer/breeder partners in developing the LOF production process by utilizing cattle waste (urine) as raw material. In addition, it is also to increase the ability of partners to produce local microorganisms (LoM) from natural ingredients. This activity has been carried out in Barebbo Village, Barebbo District, Bone Regency. The partner group involved is the farmer-livestock group “Mase-mase”. Several technology packages that have been disseminated include: 1) urine processing technology into LOF, 2) local microorganism (LoM) manufacturing technology using natural ingredients, 3) application of regression analysis and Coub Douglass function to optimize profits in beef cattle farming. The method of implementing the activities uses training methods in the form of face-to-face (offline) which is continued with direct practice. Furthermore, the process of technology assistance and monitoring is carried out. The results of the evaluation of the implementation of activities indicate that the application of technology has a very significant impact on the capacity of partners. The process of urine production into LOF can reduce the amount of liquid waste from cattle business which has a direct impact on environmental improvement.
PELATIHAN PEMBUATAN ALAT PERMAINAN EDUKATIF (APE) BAGI GURU PAUD DI KP. CIKAREES, GARUT, PADA MASA NEW NORMAL
Authors: Sulastri Resti , Fuada Syifaul
Published: June 2022

A workshop on making educational toy tools (in Bahasa Indonesia is “APE”) has been held for early childhood teachers in the New Normal period at Kp. Cikarees RT 04 RW 04 Desa Padasuka Kec. Cibatu Kab. Garut-West Java on Tuesday, December 22, 2020. This offline workshop aims to improve early childhood teachers' skills and creativity in making APE. This workshop is one of several community services of the 2020 Thematic KKN PPD Covid-19 Universitas Pendidikan Indonesia. The APE used for this workshop is readily available materials and adapted to the learning themes in early childhood school of Kp. Cikarees, i.e., Five Senses, Profession, and Fruits. A total of 4 early childhood teachers attended this workshop: two teachers from the Kober Miftahusaadah school and two teachers from the At-Thohariah Kindergarten school. This workshop is composed of 3 stages: 1) the Preparation stage, 2) The main stage, which contains the explanation of the theory, practice (Making APE), and the last is the evaluation stage by giving a questionnaire to each of the invited teachers in the workshop. The implementation of this workshop runs smoothly so that the program objectives can be achieved; that is, the early childhood teachers gain a deeper understanding of APE, and their creativity in making APE is increased.