bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessing the Effect of Fe2O3 Nanoparticles on Catalase Activity in Patients with Chronic Periodontitis: In Vitro study and Molecular Docking
Authors: Hatem Sara A. , Nasif Zaizafon N. , Al-Rubaee Eaman A. S.
Published: July 2024

Periodontal disease, also known as gum disease, is a chronic inflammatory condition that affects the supporting structures of the teeth, including the gums and underlying bone. It is primarily caused by a bacterial infection resulting from poor oral hygiene practices. The main objectives of the current study were to synthesize iron oxide nanoparticles (Fe2O3-NPs) and their characteristics were analyzed through UV, SEM, and X-ray analysis. Additionally, the dispersion of the synthesized NPs was investigated using UV and TEM techniques. The study also aimed to assess the kinetic behavior and the impact of Fe2O3-NPs on catalase activity in the saliva of the patient and control groups. The findings revealed a significant increase in catalase activity (p>0.05) in both serum and saliva of all patient groups compared to the control group. The UV-visible spectrum shows that the absorption peaks for synthesized α- and γ-iron oxide nanoparticles was at 225 nm. According to the SEM image analysis, the primary particle size of the nano-particles is approximately 26.8 nm. The X-ray diffraction results indicate that the Fe2O3-NPs range in size from 14 nm to 26 nm. UV and TEM study conclude that water a suitable solvent for Fe2O3-NPs dispersion on kinetic study of catalase (CAT) activity. The kinetic data cleared that the α-Fe2O3-NPs have an inhibitory effect for the total activity of salivary CAT in the samples of both healthy and patients with chronic periodontitis. Lineweaver–Burk graph showed that (α-Fe2O3) inhibit catalase by un comp. inhibition. γ-Fe2O3-NPs inhibited total salivary CAT activity in healthy and patients with chronic periodontitis samples. Lineweaver –Burk graph showed that (γ-Fe2O3) inhibit catalase by uncompetitive inhibition.
Up-Regulation of microRNA-34a in Women with Systemic Lupus Erythematosus
Authors: Abdullah Wissam L. , Abed Reema M.
Published: July 2024

Systemic Lupus Erythematosus (SLE) is a chronic systemic autoimmune disease with multiple contributing factors. It is characterized by the immune system's inability to tolerate autoantigens such as nuclear antigens. The objective of this study is to evaluate the expression of microRNA-34a in relation to the incidence and occurrence of SLE in Iraqi women using quantitative real-time PCR and to determine its potential relationship with various demographic and laboratory parameters and disease activity. This investigation enrolled 100 healthy controls with a mean age of 31.68 years and 100 SLE patients, all of whom were women with a mean age of 32.85 years and  a disease duration of 9.00 (6.75) years. The mean of the Systemic Lupus Erythematosus disease activity index (SLEDAI-2k) score was 10.860±3.275. Erythrocyte sedimentation rate, C-reactive protein, urea, and creatinine were significantly higher (50.00 vs. 10.00 mm/h, 16.70 vs. 0.650 mg/dl, 58.00 vs. 33.00 mg/l, and 1.550 vs. 0.700 mg/l, respectively), while hemoglobin, white blood cells, and Complement 3 and Complement 4 were significantly lower (8.40 vs. 13.00 g/dl, 3.500 vs. 6.800 x 109  /L, 74.00 vs. 130.00 mg/dl, and 10.00 vs. 13.50 mg/dl, respectively) in patients with SLE compared with controls (P≤ 0.001). The analysis of anti-nuclear antibodies (ANA) in patients showed that 89% have ANA and 95% have anti-double-stranded DNA (anti-dsDNA). Also, the findings revealed a significant increase in microRNA-34a expression with fold change (5.19 ±0.48) when compared to the fold change mean in controls (1.00 ±0.00). There is no evidence for any correlation between microRNA-34a fold change and any laboratory or demographic examination of the illness in the present study except for age and BMI. In addition, receiver operating characteristic (ROC) analysis was performed on SLE patients to establish the diagnostic accuracy of microRNA-34a in differentiating SLE patients from controls. The specificity and sensitivity of microRNA-34a were 98% and 100%, respectively. The area under the curve (AUC) was 0.990, and the cutoff point was 1.050. This indicates that the identified microRNA-34a may represent strong biomarkers for SLE disorders.
Slope Stability Analysis Some Selected Sites at Bajalia Anticline in Missan Governorate, Eastern Iraq
Authors: Al-Zubaydi Jaffar H.Ali , Al-Turaihi Ahmed S.
Published: July 2024

In this study, rock stability has been assessed to pinpoint the critical factors affecting slope instability. The discontinuity data collected during the field surveys was evaluated using stereograph projection. Bai Hassan, Mukdadiya, and Injana Formations that were exposed in the research region show slope collapses, ranging in severity from most to least in terms of secondary toppling and rock fall. The characteristics of the rock discontinuities determine the kind and extent of hazards. According to this study, warning signs and fencing should be used to prevent people from walking along the edges of the slopes in the Bajalia anticline and the areas around to alert them of potential failure threats.
Generalizations of Supplemented and Lifting Semimodules
Authors: Alwan Ahmed H.
Published: July 2024

In this paper, principally supplemented (-supplemented), and principally lifting (-lifting) semimodules are defined as generalizations of principally supplemented (-supplemented), and principally lifting (-lifting) modules. Let  be a semiring. An -semimodule  is called a principally supplemented (-supplemented) semimodule, if for all  there exists a subsemimodule  of  with  and  small (-small) in . In this paper, we examine properties of principally -supplemented semimodules and generalize results on principally -supplemented modules to semimodules. Besides, we characterize -semiperfect semimodules as a generalization of -semiperfect modules.
An Advanced Approach for Predicting ROP Stages: Deep Learning Algorithms and Belief Function Technique
Authors: Salih Nazar , Ksantini Mohamed , Hussein Nebras , Ben Halima Donia , Abdul Razzaq Ali , Ahmed Sohaib
Published: July 2024

A significant cause of blindness in preterm infants is retinal retinopathy of prematurity (ROP). Early detection and intervention are essential for preventing visual loss. This study proposes an advanced approach for predicting ROP stages using deep learning algorithms and belief function theory. Three steps comprise the suggested technique: image pre-processing, feature extraction using deep learning models, and classification utilizing belief function theory. We used a dataset of 3720 retinal images from premature infants and achieved a classification accuracy of 95.57% for predicting ROP stages. Our results demonstrate the effectiveness of deep learning algorithms and belief function theory in ROP diagnosis. This strategy can increase the efficacy and precision of ROP diagnosis, improving the treatment course for premature infants at risk of vision loss.
FIXED POINT THEOREM FOR MULTIVALUED (Ï•, F, Ï‰)-CONTRACTION MAPPING ON COMPLETE METRIC SPACE
Authors: Dethan Yovita Margerita , Pasangka Irvandi Gorby
Published: July 2024

Dalam penelitan ini, didefinisikan suatu pemetaan baru yang diberi nama pemetaan kontraksi-$(\phi, F,\omega)$ bernilai banyak. Pemetaan ini merupakan hasil modifikasi dari pemetaan kontraksi-$(\phi,F)$ yang diberikan oleh Wardowski. Selanjutnya dibuktikan eksistensi titik tetap dari pemetaan kontraksi-$(\phi, F,\omega)$ bernilai banyak, dan diperoleh beberapa akibat dari teorema tersebut.
OPTIMASI BIAYA DISTRIBUSI BERAS SEJAHTERA PERUM BULOG DIVRE SUMATERA BARAT DENGAN IMPROVED VOGELâ€™S APPROXIMATION METHOD
Authors: Bahri Susila , Karimi Arief Farhan , Baqi Ahmad Iqbal
Published: July 2024

Perusahaan Umum Badan Urusan Logistik Divisi Regional Sumatera Barat (Perum Bulog Divre Sumatera Barat) adalah perusahaan yang ditunjuk un- tuk mendistribusikan beras sejahtera ke berbagai daerah demi memenuhi kebutuhan pokok penduduk Sumatera Barat. Untuk meminimumkan biaya, dibutuhkan peren- canaan matang sehingga biaya distribusi yang dikeluarkan Perum menjadi optimal. Un- tuk menyelesaikan masalah transportasi pendistribusian kebutuhan pokok tersebut, di- gunakan Improved Vogels Approximation Method (IVAM). Selanjutya, uji optimalisasi biaya dilakukan dengan menggunakan Modified Distribution Method (MODI). Penelitian ini menghasilkan biaya distribusi adalah Rp 124.149.070 sedangkan biaya pengeluaran tanpa penggunaan metode dihasilkan sebesar Rp 126.259.188. Oleh karea itu, terdapat penghematan sebesar Rp 2.001.938.
Derecho a la alimentación adecuada, pérdidas y desperdicios, y géneros. Problemáticas superpuestas: ¿respuestas contrapuestas?
Authors: Castagnari Valentina , Valentini Mariano G.
Published: July 2024

Las dietas malsanas, factores de riesgo prevenibles de enfermedades no transmisibles (ENT), constituyen un reto creciente, que coexiste con problemas preexistentes y persistentes de desnutrición. Éstos, además, conviven e interactúan sinérgicamente con dinámicas de cambio climático, que amenazan la sostenibilidad de los sistemas alimentarios, y son atravesadas silenciosamente por dinámicas de géneros. Los Estados han adoptado medidas para abordar estas problemáticas, entre ellas, normas para promover la alimentación saludable y prevenir la pérdida y desperdicios de alimentos. No obstante, las respuestas estatales a problemas cuyas causas son frecuentemente comunes se adoptan de manera fragmentada, con elementos contradictorios entre sí y con el marco de derechos humanos. El presente trabajo presenta las anteriores discusiones comparando las iniciativas regulatorias de tres países, Colombia, Chile y Argentina, analizando su compatibilidad hacia el interior y el marco internacional de derechos humanos. Finalmente, plantea ideas disparadoras para reconciliar las diversas agendas desde una mirada integral.
Efecto de la red de urgencias sobre el tiempo de atención del paciente traumatizado en el Hospital Universitario del Valle, Cali, Colombia
Authors: Zamudio Alexandra , Castro Inés
Published: July 2024

En el Hospital Universitario del Valle (HUV), Cali, Colombia, se realizó un estudio observacional para demostrar el efecto de la red de urgencias sobre el tiempo necesario en la solución de los problemas del paciente traumatizado. Se compararon 2 poblaciones, la que se obtuvo antes que se estableciera la red y la que se produjo como resultado de las medidas generadas por ella. Se intentó demostrar si la diferencia era el producto de la aplicación de tal variable. Las muestras se manejaron en dos períodos; el primero cobijó un total de 29 pacientes que correspondían a 25% de la población y en el segundo período, cuando se cobijó a 100% de la población consultante, se obtuvieron 15 pacientes. Se pudo demostrar que la red de emergencia contribuyó a descongestionar el Servicio de Urgencias del HUV, pues el número de pacientes atendidos por día disminuyó en 27%; además, se lograron agilizar las distintas etapas de atención por las que pasa el paciente víctima de trauma.
Carcinoma adenoide quístico de glándulas salivales. Experiencia en el Hospital Royal Marsden, Londres, Inglaterra
Authors: Rubiano Jaime , Pérez María Victoria
Published: July 2024

Se revisa la experiencia del Hospital Royal Masden de Londres, con 38 casos de carcinoma adenoide quístico de glándulas salivales, entre 1960 y 1985. Con los modelos de Kaplan-Meir para sobrevida y el de Cox para factores pronósticos, se encontró que la edad, el sexo y la localización no influyen en la sobrevida y sólo el estadío clínico y la radioterapia afectan la sobrevida y el control local. La cirugía no debe ser radical y sólo una excisión local amplia del tumor, seguida de radioterapia cuando esté indicada, es el tratamiento de elección. La sobrevida fue de 74% a 5 años y 58% a 10 años.
Parasitic protozoa transmission by drinking water
Authors: Solarte Yezid , Peña Miguel , Madera Carlos
Published: July 2024

The pathogenic protozoa Cryptosporidium sp. and Giardia sp. showed their infectivity and negative effects on the health of thousands of people in both developed and developing countries. Protozoa have ambient resistant stages that permit survived to physical and chemical treatment of drinking water. This risk is mainly related to the consumption of water whose microbiological quality indicators typically fulfill with current standards (fecal coliforms and Escherichia coli). Likewise, the discovery of new pathogens is calling for the development of new microbiological quality indicators that allow the production of really safe goods and services such as water for human consumption. Herein the authors present a literature review showing the impact of this microbiological risk in different populations.
Overview of short bowel syndrome and intestinal transplantation.
Authors: Duro Debora , Kamin Daniel
Published: July 2024

Short bowel syndrome is at once a surgical, medical, and a disorder, with potential for life-threatening complications as well as eventual independence from artificial nutrition. Navigating through the diagnostic and therapeutic decisions is ideally accomplished by a multidisciplinary team comprised of nutrition, pharmacy, social work, medicine, and surgery. Early identification of patients at risk for long-term PN-dependency is the first step towards avoiding severe complications. Close monitoring of nutritional status, steady and early introduction of enteral nutrition, and aggressive prevention, diagnosis and treatment of infections such as line sepsis, and bacterial overgrowth can significantly improve prognosis. Intestinal transplantation is an emerging treatment that may be considered when intestinal failure is irreversible and children are suffering from serious complications related to TPN administration.
Frequency and variability of the dental morphology in African-Colombian children of a school institution of Puerto Tejada, Cauca, Colombia.
Authors: Rocha Lorena , Rivas Harold , Moreno Freddy
Published: July 2024

Objectives: To assess the frequency and variability of eleven non-metric dental crown traits (winging, shovel-shape, double shovel shape, Carabelli trait, deflecting wrinkle, protostylid, groove pattern, cusp number, sixth and seventh cusps) in permanent (UI1/UI2/UM1/LM1) teeth, in order to understanding the ethnic influence and the biological distance of the sample in study. Materials and methods: In this descriptive and quantitative study, frequency and variability of twelve non-metric dental crown traits were analyzed, through the ASUDAS System, in dental casts from 84 African-Colombian children of both sexes (42 females and 42 males), in mixed-dentition from Puerto Tejada, Cauca (Colombia) inhabitants. Results: High frequencies of Carabelli trait in grade 5; and +5 y +6 groove patterns, suggests Western dental complex influence. High frequencies of protostylid (P point or foramen secum) and deflecting wrinkle that suggest Mongoloid influence from the miscegenation with regional indigenous groups were observed. Winging, shovel-shape, double shovel, cusp number and cusp 6 showed low frequencies. Bilateral symmetry and absence of sexual dimorphism were demonstrated (except winging, shovel-shape and protostylid).
Noise levels in the «Hospital Universitario del Valle» newborn intensive care unit «Cirena», Cali, Colombia.
Authors: Fajardo Diana Lorena , Gallego Sonia Yurany , Argote Luz Ángela
Published: July 2024

Introduction:  The high risk newborn babies requires special care and treatment then they have to be move to a exclusive area of the new born intensive care unit (Cirena), where they stay in the hospital during long periods of time and they are more vulnerable to multiple physics and environmental aggressions like noise that can make a negative influence on their clinical situation and post evolution. Objective: Determine level and noise levels in the newborn intensive care unit (Cirena), to planning nurse care to make a contribution to the well being of the new born babies. Methodology:  This is a prospective descriptive study that quantified the sound intensity in different areas of the unit, with a digital sound meter, the study identifies some hours of the day and the noise increment related activities in CIRENA, according to international standards. The statistic analysis was made with SPSS program V 11.5. Results: The study shows that the CIRENA´s noise level is above of the allowed limit, the maximum registered value was 73.6 dB and the minimum value was 46.5 dB, the main source of noise was the people in the room. All the health team needs to keep in mind that is necessary to apply strategies to decrease the noise level  and in this way, reduce the stress level for kids in the hospital.
Teachers performance evaluation: the experience of the Dentist Academic Program of the Universidad del Valle.
Authors: Villavicencio Judy Elena
Published: July 2024

Background: Teaching activity evaluation as a result of students’ opinion is a process that has been developing in the Dentist Academic Program for approximately ten years. This kind of evaluation has its formal origin in American and European universities during the 1920´s. Objective: To analyze the results of the teacher’s performance trends according to the inquiries undertaken by the Dentist Academic Program students of the Universidad del Valle from 2005 to 2007, and to determine if there are significant differences in the teacher’s evaluation results according to academic ranks and program formation areas. Method: A descriptive transversal study was carried out, with  teaching evaluation questionnaires undertaken by students of the Dentist Academic Program of the Universidad del Valle during 2005 and 2007. Results: A total of 474 teachers were evaluated. The average results during the five semesters evaluated for the teachers were 4.4. It was found that in four of the five semesters analyzed do exist significant differences in the results of the evaluation by the students at the level of teachers’ academic ranks. Additionally, there were no significant differences in the results of the students’ evaluation for the Academic Program Areas.
Exercise induced hemolysis: relation between the activity of glucose-6-phosphate dehydrogenase and the magnitude of the hemolysis.
Authors: Bonilla Javier Fernando , Palomino Fernando
Published: July 2024

Introduction: Oxidation and hemolysis associated with physical exercise, moderate and severe, have been studied by several investigations, but only in the most recent have been evaluated how the variations of the genetic determined mechanisms for antioxidative enzymatic erytrocytic capacity, contribute to establish different levels of susceptibility to the hemolysis induced trough exercise, however, those studies have mainly been made on non sedentary subjects with deficiency of enzyme G6PD. Purpose: The objective of this study was to establish if there is either yes or not a relationship between the activity level of erythrocytic activity of the enzyme G6PD and the hemolysis grade, induced by exercise in adult healthy sedentary men and after an experimental bout of moderate exercise pre-exhaustive and equivalent in modality and intensity. Methods: Twenty five men, sedentary and seemingly healthy, were evaluated after an exercise session of 1 hour over a cycloergometer, with 70% of VO2peak previously founded.  On the basis of plasmatic Hb, the proportion of hemolysis and haptoglobin consumed, taking in account the variation of plasma haptoglobin and intravascular hemolysis after and at least three hours post-exercise, were calculated. Results: The experimental subjects presented laboratory evidence (free plasma hemoglobin, percentage of hemolysis and haptoglobin) of intravascular hemolysis immediately after and at least past three hours of exercise bouts. Conclusion: The grade of hemolysis had an inversely significative correlation with the G6PD activity and, this intensity had a significative different behaviour below the percentil 40 media founded for G6PD and above of it. Thus, the oxidative hemolytic response in sedentary and healthy individuals who had lower levels G6PD activity with one bout of exercise with 70% of VO2peak was highly variable.
Gastroschisis at hospital of third level in Cali, Colombia, from March 2004 to February 2006.
Authors: Pachajoa Harry , Saldarriaga Wilmar , Isaza Carolina
Published: July 2024

Introduction: Gastroschisis is a congenital malformation in the abdominal wall, whose prevalence ranges between 0.66 and 2.7 per 10,000 births. In the last years has been detected an increase of the prevalence has been detected in recent years. This is associated to an increasing proportion of teenage mothers and to new etiologic factors like exposition to specific teratogens and nutritional deficiencies. Objectives: To determine the prevalence of newborns with gastroschisis born at Hospital Universitario del Valle (HUV) in Cali, during a two-year period and to evaluate the association between demographic factors of the parents and the occurrence of gastrosquisis. Methods: An observational and descriptive study was made, considering as universe all newborns at Hospital Universitario del Valle in Cali, Colombia, between March 2004 and February 2006, to determine the occurrence of newborns with gastroschisis. Results: During the time of the study, 16 children were born with gastrosquisis from a total of 14,452 births, representing a prevalence of 11.1 per 10,000 births, of 7.8 per 10,000 live newborns and of 103.5 in dead newborns. We found the mothers’ average age at 18.3. In August 2005 at Hospital Universitario del Valle there were 611 births of which 5 were born with gastroschisis, showing a prevalence of 81.8 per 10,000 and 1 per 122 newborns. Conclusions: The prevalence of gastrosquisis at HUV of 11.1 per 10,000 births is one of the highest reported in the literature. Maternal age under 20 years and being the first pregnancy were found in most of the mothers of newborns with gastroschisis. 5 cases of gastroschisis in August 2005 at HUV suggest a cluster for this malformation.
Documental revision of the natural products authorized for marketing in Colombia
Authors: Guevara Hellen Astrid , Luengas Pilar Ester , Garavito Giovanny
Published: July 2024

Introduction: The group of natural products has gained much interest in recent years because of the popular belief that they are effective and more secure than synthetic medications, or because of recent health tendencies seeking to supplement nutrition. Objective: To describe the group of natural products from a sanitary authority point of view. Methodology: Observational, descriptive, cross-sectional study from the universe of Drug approvals of Natural Products presented by a database from the Instituto Nacional de Vigilancia de Medicamentos y Alimentos (Colombian Sanitary Authority). Results: Nearly half of the natural products legally accepted for marketing are herbal medicines and the other half are dietary supplements, along with specific-use products. The vegetable species with the greatest number of commercialization authorizations is artichoke Cynara scolymus  (alcachofa), followed by calendula (Calendula officinalis), valerian (Valeriana officinalis), garlic (Allium sativum), and ginkgo (Ginkgo biloba).  Foreign species predominate in the fabrication of commercialized herbal medicines.  A novel classification is proposed of the plant organ or drug employed in the production with which it is evident that leaves are used more with respect to any other plant organ.  Capsules, tablets, and solutions are the predominant pharmaceutical forms. Conclusions: The group of natural products has demonstrated growing evolution in drug approvals in these last years; for the herbal medicines subgroup, national production predominates even though there is a minimum use of native species; while for dietary supplements and specific use products subgroups importation is predominant, evidencing the necessity for national policies to articulate the norms with Colombian needs and to stimulate the valorisation and sustainable use of our natural resources with adequate profit for the communities that will be reflected in greater national production using resources in which Colombia has competitive advantages.
Policy Brief No. 2. Comprehensive habitat upgrading with an intersectional approach
Authors: Franco Calderón Ángela María , Millan Franco Gynna , Jiménez Avilés Ángela María , Jaramillo Díaz Isabella
Published: July 2024

Latin America and the Caribbean (LAC) is the most urbanised region in the world, with 80% of its population living in cities (ECLAC, 2012). As in many countries of the Global South, in the Latin American city outskirts there is a significant number of people living in poverty, including migrants who have arrived for economic reasons or forced displacement. These people have found a housing option in self-built neighbourhoods, but having a roof does not guarantee a quality of life. Governments have implemented upgrading programmes to address this situation, to provide basic infrastructure, housing, and titling. However, projects developed under this approach have left aside social and cultural factors such as population diversity and local knowledge. This policy brief provides recommendations for implementing the Comprehensive Habitat Upgrading with an Intersectional Approach (CHU-I) as an instrument to formulate projects in line with local realities, and presents a summary of its implementation in Cali, Colombia.
Cervical Cancer During the COVID-19 Pandemic in Rural Communities of Ayacucho
Authors: Orellana de Piscoya Lucy ,   Universidad Nacional San Cristóbal de Huamanga, Ayacucho. Lima, Perú.
Published: July 2024

Introduction: Due to the COVID-19 pandemic, vulnerable rural women faced significant challenges. Objective: To explore the situation of cervical cancer during the pandemic from an intercultural perspective among rural women in Ayacucho in 2021. Methodology: Mixed-method research with a concurrent triangulation design. Sample: Healthcare providers and rural women. Purposeful and reasoned sampling. Techniques: Surveys, in-depth interviews. Data analysis: Data systematization using Excel, SPSS for quantitative data, and Atlas.ti for qualitative data. Level of validity and confidence: triangulation. Results: Information from surveys and interviews was contrasted, revealing that the problem may have alternative solutions within the knowledge of the same communities. Conclusion: Women reported lack of awareness, insufficient information in the Quechua language, and undervaluation of their traditional knowledge. Fear and contagion concerns prevented them from seeking healthcare services. Services were reduced, redirected, or discontinued, often due to budget constraints.
Efecto de la Averrhoa carambola L. en la piel en un modelo animal de cicatrización hipertrófica
Authors: Córdova-Aguilar Alberto ,   Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima-Perú, Mujica-Albán Elydia , Ortiz-Sánchez José , Suárez-Cunza Silvia , Iglesias-Bustamante Rodrigo , Blanco-Victorio Daniel ,   Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima-Perú.,   Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima-Perú.,   Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima-Perú.,   Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima-Perú.,   Facultad de Ciencias e Ingeniería, Universidad Peruana Cayetano Heredia, Lima-Perú.
Published: July 2024

Introduction: Hypertrophic scarring in the skin represents a serious global public health problem, as it physically and emotionally affects people who suffer from it. This makes it necessary to investigate new alternatives for its prevention and treatment. The objective of the study was to compare the effect of Averrhoa Carambola L. (star fruit) on the skin under an animal model of hypertrophic healing. Methods: Experimental study; 10 male New Zealand breed rabbits were used, between 3 and 4 months old, with an average weight of 3 to 3.5Kg. The formation of hypertrophic scars in the ears of rabbits was induced under the model described by Morris et al. One of the groups received 1 mL of a 10% aqueous solution of the lyophilized star fruit, while the other received 1 mL of triamcinolone acetonide; in both groups the application was intralesional and weekly in a month. After the treatment, under sedation, only the hypertrophic scars were extracted using a biopsy punch and the tissues were preserved in 10% formalin for subsequent pathological examination. Results: The group that received star fruit solution significantly improved the dermis and epidermis in the hypertrophic scars on the ears of rabbits that received treatment. When compared with the group that received triamcinolone acetonide, there were no statistically significant differences. Conclusion: The lyophilized aqueous extract of star fruit at 10% demonstrated a similar effect compare to triamcinolone acetonide (treatment of choice) in reducing the fibrosis of hypertrophic scars in the ears of rabbits.
Integration of the Pancasila student profile in physical education learning
Authors: Nopiyanto Yahya Eko , Pujianto Dian , Maisarah Ira , Wibowo Cahyo , Kardi Ipa Sari
Published: July 2024

Background: The integration of the Pancasila Student Profile (PSP) in physical education (PE) learning represents a significant endeavour to align educational practices with national values and aspirations. Through rigorous research and thoughtful implementation strategies, educators can harness the transformative potential of PE to cultivate socially responsible citizens who embody the spirit of Pancasila in their actions and interactions within the broader Indonesian society. Research Objectives: The aim of this research is to determine the level of integration of Pancasila student profiles in physical education learning in Bengkulu City. Methods: The quantitative research method was used to achieve this goal. The sample was 432 students whose taken randomly among the elementary school, middle school, and high school. The instrument in this research was a questionnaire. The data was analysed using the mean ideal and the deviation standard ideal. Finding/Results: The integration of the PSP in schools in the city of Bengkulu has four different categories. In the very high category, the frequency is 51; in the high category, the frequency is 301; in the moderate category, the frequency is 78; and in the low category, the frequency is 2. Conclusion: The Pancasila profile of students learning PE in Bengkulu City is well implemented. The novelty of integrating the PSP into PE learning lies in its unique approach to instilling national values and character education in the PE curriculum. This integration aims to encourage holistic student development by combining physical education learning with the values of God Almighty, independence, global diversity, cooperation, critical thinking, and creative thinking, which are the core of the Pancasila student profile.
Physical education teacher skills in preparing HOTS lesson plans and their contribution to teaching performance
Authors: Hardiansyah Sefri , Blegur Jusuf
Published: July 2024

Background: Higher-order thinking skills (HOTS) are 21st-century thinking skills needed by students to survive the demands of the current era. However, the problem is that teachers often do not optimally include HOTS in the lesson plan and the implementation of learning. Research Objective: This study aimed to investigate the relationship between the teacher's skill in preparing HOTS lesson plans and the teacher's performance in applying them to physical education. Methods: This type of research is correlational using two research variables: the teacher's skills in preparing HOTS lesson plans and teaching performance. The participants were 28 physical education teachers (men = 21, women = 7) who participated in the Teacher Professional Education Programme at Universitas Negeri Padang in 2022. The HOTS lesson plan data and teacher teaching videos were taken from the documented performance test results (PDF files and teaching videos). Data analysis used regression with the help of SPSS version 25. Findings/Results: The results showed that α < 0.05 (0.007) with a regression value of 2.923 means that the teacher's skills in preparing HOTS lesson plans are positively determined by their performance in teaching HOTS to students. The contribution made by the teacher's ability to prepare HOTS lesson plans to teacher teaching performance is 24.70%. Conclusion: Teachers who can prepare a good HOTS lesson plan can provide a guarantee for their HOTS teaching performance. Thus, the more detailed the teacher formulates the goals, objectives, activities, media, and HOTS assessments, the more it helps them determine their teaching performance that encourages their students' HOTS.
Enhancement of basic tennis technical skills: Game and drill training methods of male athletes reviewed by age group
Authors: Putri Alifia Ramadhina , Sugiyanto  , Riyadi Slamet
Published: July 2024

Background Problems: The lack of variety in exercises applied by coaches makes players feel bored, so they must be given training variations by looking at training methods that significantly improve basic tennis technique skills between game training methods and drills. Research Objectives: This study aims to determine differences in the effect of game and drill training methods on improving basic tennis technical skills based on the age groups of 10-12 years and 13-15 years. Methods: In this context, the method used was experimental research with a 2x2 factorial design. The sample consisted of 24 male athletes in Lampung who were separated into 4 groups. Findings and Results: (i) There are differences in the effect of game practice and drill methods on improving basic tennis technique skills. (ii) There is a difference in improving basic tennis technique skills between the age groups of 10-12 years and 13-15 years. (iii) There is an influence of interaction between training methods and age groups on improving basic tennis technique skills. Conclusion: The age group 10-12 years is more appropriate if given the game training method, and the age group 13-15 years is more appropriate if given the practice training method. The findings of this study provide an important contribution by highlighting the importance of both applied training methods for basic tennis technique. This training method is also adapted for age-based characteristics. Therefore, the recommendation to use game and drill training methods as part of tennis training can help athletes cope with intense playing conditions. Based on the analysis above, the novelty of the research developed by the researcher was two exercise methods compared, two age groups that were sampled, and research instruments using International Tennis Number (ITN) On Court Assessment. Researchers used game and drill training methods that could affect the sample after treatment. Different from previous research, the sample used was male athletes aged 10-15 years.
FROM THE HISTORY OF ECOLOGY OF DAGESTAN
Authors: Алилова К.М.
Published: July 2024

На основе литературных и архивных данных рассматривается история и современное состояние экологических воззрений в Дагестане. Предметом исследования является отношение к природе в Дагестане с древних времен и по сегодняшний день. Говорится о важности наблюдения за природой родных мест, о том, как необходимо беречь природу. Подчеркивается большой вклад народной экологии в деле сохранения природы. Рассказывается о преданиях, которые дошли до наших времен, о том, как люди охраняли водные источники, леса, как культивировалась любовь к родному краю. Приводятся примеры наказания для тех, кто разрушал природу. Значительный интерес представляет проблема экологического права в Дагестане, то, как в дореволюционный период регулировались отношения между человеком и окружающей средой. Предлагается возрождать традиции предков по охране природы с учетом современных этнополитических, культурных, социально-экономических особенностей. Говорится о том, что междисциплинарное исследование природы экологами и историками очень полезно для поиска путей решения экологических проблем.

On the basis of the literary and archived data is examined history and modern state of ecological views in Daghestan. The article of research is attitude toward nature in Daghestan from ancient times and for today. Talked about importance of watching nature of native places, about that, how it is necessary to save nature. The large contribution of folk ecology is underlined to the matter of maintenance of nature. Told about legends that reached to our times, about that, how people guarded water sources, forests, as love was cultivated to the native edge. Examples of punishment are made for those, who destroyed nature. Considerable interest is presented by the problem of ecolaw in Daghestan, then, as in a pre-revolution period relations were regulated between a man and environment. It is suggested to revive traditions of ancestors on conservancy taking into account modern этнополитических, cultural, socio-economic features. In the article talked that междисцплинарное research of nature by eclogues and historians very usefully to the search of ways of decision of ecological problems.
LOSS OF WAVE ENERGY DUE TO TSUNAMI PENETRATION INTO THE OKHOTSK SEA THROUGH THE STRAITS OF THE KURIL ISLANDS
Authors: Костенко И.С. , Зайцев А.И. , Кузин В.Д.
Published: July 2024

Представлена количественная оценка защитной роли Курильских островов при проникновении цунами из Тихого океана в Охотское море. Для этого проведена серия вычислительных экспериментов распространения волн от гипотетического очага цунами с использованием разных батиметрий: с Курильскими островами, без Курильских островов и со стенкой в районе Курильских островов. Проведена оценка районов максимального усиления волн в районе Курильских островов и в акватории Охотского моря. По результатам численных экспериментов проведен анализ изменения энергии цунами при проходе через проливы Курильских островов в Охотское море.

The paper presents a quantitative assessment of the protective role of the Kuril Islands in the penetration of the tsunami from the Pacifi c Ocean into the Okhotsk Sea. For this purpose, a series of computational experiments of wave propagation from a hypothetical tsunami source using different bathymetries: with the Kuril Islands, without the Kuril Islands and with the wall near the Kuril Islands. The assessment of areas of maximum wave amplifi cation in the Kuril Islands and in the Okhotsk Sea is carried out. According to the results of numerical experiments, the analysis of the Tsunami energy changes during the passage through the Straits of the Kuril Islands in the Okhotsk Sea was carried out.
AEROSOL, ATMOSPHERIC VORTEX ACTIVITY AND TURBULENCE
Authors: ИЖОВКИНА Н.И. , АРТЕХА С.Н. , ЕРОХИН Н.С. , МИХАЙЛОВСКАЯ Л.А.
Published: July 2024

The interaction between the cyclone coming from the Atlantic side and the anticyclone above the center of the European part of Russia depends on the stability of the anticyclone. The blocking of anticyclones is observed mainly in the summer. Blocking anticyclones are formed over Siberia too. It is shown that the vortex activity of the atmosphere, jet flows and turbulence in it are associated with inhomogeneous cellular distributions of atmospheric pollution. Part of the energy of powerful atmospheric vortex structures, such as tornadoes, cyclones and anticyclones, is generated by aerosol plasma vortices.
THE FIRST ELECTRIC VEHICLES INVENTIONS IN RUSSIA
Authors: Смык А.Ф.
Published: July 2024

В работе исследованы вопросы изобретательской деятельности одного из талантливых представителей российского инженерного сообщества конца ХIХ–начала ХХ вв. Ипполита Владимировича Романова, которая была связана с созданием первых в нашей стране электрических транспортных средств. В Петербурге при непосредственном участии известного инженера и предпринимателя П.А. Фрезе были построены двухместные электромобили системы Романова, а также электрический омнибус. В самом начале ХХ в. русские инженеры развивали идеи городского электрического транспорта – трамваев, электромобилей и омнибусов, для массового производства которых требовалась государственная поддержка. В 1900 г. И.В. Романовым был получен патент в России, а в 1905 г. аналогичный патент в Соединенных Штатах Америки на подвесную железную дорогу, именовавшуюся дорогой «системы инженера Романова». В Гатчине прошли успешные испытания монорельсовой дороги на электротяге, построенной по проекту Романова.

The paper investigates the issues of the inventive activity of one of the talented representatives of the Russian engineering community of the late XIX – early XX centuries Ippolit Romanov, which was associated with the creation of the fi rst in our country electric vehicles. With the direct participation of the famous engineer P. Freze, two-seater Romanov electric vehicles and an electric omnibus were built in Peterburg. At the very beginning of the twentieth century, Russian engineers developed the idea of urban electric transport – trams, electric vehicles and omnibuses, for the mass production of which required state support. In 1900 I. Romanov received a patent in Russia, and in 1905 a similar patent in the United States of America for the suspended railway, called the road «systems of engineer Romanov». In Gatchina were successfully tested monorail electric built under the project Romanova.
Understanding confidence in Banks: the role of personal characteristics and Artificial Intelligence
Authors: Gómez-Martínez Raúl , Pérez-González Benito , Medrano-García María Luisa , Torres-Pruñonosa Jose
Published: July 2024

Confidence in banks and financial institutions is a cornerstone of financial stability and economic prosperity. This study investigates the relationship between personal characteristics and confidence in banks, recognizing the pivotal role of trust in shaping individuals' perceptions of financial institutions. Through a mixed-methods approach combining survey techniques and artificial intelligence modelling, we analyse data collected from a representative sample of the university community. Our findings highlight the significant influence of demographic factors such as age, gender and education level on confidence in banks. Moreover, we validate our hypothesis using metrics such as ROC Area and PRC Area, indicating the predictive power of personal characteristics in determining confidence in banks. The sensitivity analysis further elucidates the relative importance of different predictors in shaping confidence levels. The implications of our research extend to policymakers, financial institutions and researchers, offering insights for tailored interventions, customer engagement strategies, and future investigations. By deepening our understanding of the drivers of confidence in banks, this study contributes to the enhancement of financial stability and consumer trust in the banking sector.
Nilai Guna Langsung Perikanan Tangkap di Kawasan Mangrove Desa Sungai Nibung
Authors: Yustina Yustina , Nurdiansyah Syarif Irwan , Kushadiwijayanto Arie Antasari
Published: July 2024

Penelitian ini bertujuan untuk mengetahui jenis biota hasil perikanan tangkap, mengestimasi pemasukan nelayan, dan mengestimasi valuasi ekonomi perikanan tangkap secara langsung di kawasan mangrove. Metode yang digunakan pada penelitian adalah dengan melakukan penyebaran kuesioner berjumlah 43 responden. Analisis data pada penelitian ini menggunakan analisis deskriptif digunakan untuk menggambarkan atau menganalisis aktivitas pemanfaat sumber daya pada kawasan mangrove dan analisis kuantitatif untuk menghitung valuasi ekonomi kawasan mangrove. Hasil yang didapat menunjukkan terdapat 8 jenis biota perikanan tangkap yaitu kepiting, ikan gulama, ikan sembilang, ikan teri, ikan samge, gurita, udang rebon, dan udang vannamei. Hasil estimasi pemasukan nelayan Desa Sungai Nibung Rp. 2.014.544.000. Luas kawasan mangrove 8000 ha maka nilai ekonomi setiap meter persegi area panen adalah Rp. 439.217.
Pinpointing the Onset of Water Harvesting in Reticular Frameworks from Structure
Authors: Nguyen Ha , Darù Andrea , Chheda Saumil , Alawadhi Ali , Neumann S. Ephraim , Wang Lifen , Bai Xuedong , Alawad Majed , Borgs Christian , Chayes Jennifer , Sauer Joachim , Gagliardi Laura , Yaghi Omar
Published: July 2024

Covalent organic frameworks (COFs) have emerged as promising atmospheric water harvesters, offering a potential solution to the pressing global issue of water scarcity, which threatens millions of lives worldwide. This study presents a series of 2D COFs, including HCOF-3, HCOF-2, and a newly developed structure named COF-309, designed for optimized water harvesting performance with high working capacity at low relative humidity. To elucidate their water sorption behavior, we introduce a hydrophilicity index directly linked to intrinsic properties such as the strength and spatial density of adsorptive sites. This index is mathematically correlated with the step of water adsorption isotherms. Our correlation provides a predictive tool that extends to other microporous COFs and metal–organic frameworks, significantly enhancing the ability to predict their onset positions of water adsorption isotherms based on structural characteristics. This advancement holds the potential to guide the development of more efficient materials for atmospheric water harvesting.
Impact of Dumpsite-Derived Compost on Heavy Metal Accumulation in Cultivated Maize and Spinach.
Authors: Gideon Mathew , Anton Kuzmin , Boyi Mercy Omawumi
Published: July 2024

In many agricultural settings, the high cost of inorganic fertilizers has led farmers to resort to using compost from large dumpsites for soil amendment, in some cases, farmers even level smaller dumpsites and utilize the land for crop cultivation. This study investigated the concentrations of trace metals (Cd, Cr, Cu, Mn, Ni, Fe, Pb, Zn) in dumpsite compost, soil for cultivation, maize plants, and spinach vegetables. The study results revealed significant variations in heavy metal levels across the different samples analysed. Dumpsite compost exhibited elevated concentrations of Cd (6.00 mg/kg), Cr (89.00 mg/kg), Cu (21.00 mg/kg), Mn (101.00 mg/kg), Ni (17.12 mg/kg), Fe (1570.02 mg/kg), Pb (29.31 mg/kg), and Zn (315.18 mg/kg), surpassing the EU limits for Cd, Cu, Ni, Pb, and Zn. Conversely, soil for cultivation showed low concentrations of heavy metals, for Cd is (0.40 mg/kg), Cr (21.31 mg/kg), Cu (1.72 mg/kg), Mn (12.98 mg/kg), Ni (2.43 mg/kg), Fe (520.11 mg/kg), Pb (0.98 mg/kg), and Zn (67.31 mg/kg), still exceeding EU limits for Cd, Cr, Mn, Ni, and Zn. Maize plants and spinach vegetables showed varying levels of heavy metals, with concentrations generally lower than those in dumpsite compost but still exceeding the EU limits for several metals. The metal uptake by plants followed the order Cd > Pb > Cu > Ni > Cr > Zn > Fe > Mn. Thus, this study underscores the potential health risks associated with consuming crops grown on heavy metal loaded compost/soil and highlights the importance of continuous monitoring and remediation efforts to ensure food safety and environmental health.
Semisandwich cobalt(III) complexes as antitumor agents: high intracellular ROS activity and low in vivo toxicity
Authors: Aguado Zulima , Soriano-Jarabo Alejandro , Orduña Marcos , Cásedas Guillermo , Martínez-Vicente Pablo , García-Orduña Pilar , Moliner Cristina , del Río M. Pilar , Ricardo Rodriguez Martinez
Published: July 2024

Cp*Co(III) complexes based on the ligand 1-amidino-2-thiourea (guanylylthiourea) have been synthesized and characterized. The antitumor potential of the synthesized complexes was evaluated in vitro using HeLa and HepG2 cell lines. The cytotoxicity of the complexes was assessed, along with their effect on the production of reactive oxygen species (ROS), activation of apoptotic pathways, and cell cycle progression. Finally, the acute toxicity of the complexes was evaluated using the model organism Caenorhabditis elegans.