bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Tables 1 - 2 from Hypomethylating Therapy in an Aggressive Stroma-Rich Model of Pancreatic Carcinoma
Authors: Shakya Reena , Gonda Tamas , Quante Michael , Salas Martha , Kim Samuel , Brooks Jenna , Hirsch Steffen , Davies Justine , Cullo Angelica , Olive Kenneth , Wang Timothy C. , Szabolcs Matthias , Tycko Benjamin , Ludwig Thomas
Published: April 2023

PDF file - 421K, Supplementary Table S1A. Results from mRNA expression profiling in PDAC cells. Supplementary Table S1B. Results from mRNA expression profiling in CAFs. Supplementary Table S2A. Highest ranked gene sets from GSEA of the PDAC expression data. Supplementary Table S2B. Highest ranked gene sets from GSEA of the CAF expression data.
Supplementary Figure Legend from Hypomethylating Therapy in an Aggressive Stroma-Rich Model of Pancreatic Carcinoma
Authors: Shakya Reena , Gonda Tamas , Quante Michael , Salas Martha , Kim Samuel , Brooks Jenna , Hirsch Steffen , Davies Justine , Cullo Angelica , Olive Kenneth , Wang Timothy C. , Szabolcs Matthias , Tycko Benjamin , Ludwig Thomas
Published: April 2023

PDF file - 95K
Supplementary Figure S6 from Ex Vivo Expansion of Highly Cytotoxic Human NK Cells by Cocultivation with Irradiated Tumor Cells for Adoptive Immunotherapy
Authors: Lim Seon Ah , Kim Tae-Jin , Lee Jung Eun , Sonn Chung Hee , Kim Kwanghee , Kim Jiyoung , Choi Jong Gwon , Choi Il-Kyu , Yun Chae-Ok , Kim Jae-Hong , Yee Cassian , Kumar Vinay , Lee Kyung-Mi
Published: April 2023

Supplementary Figure S6 PDF file - 23K, KL-1-mediated NK cell expansion from PBMC of healthy and patient donors was performed as described in Materials and Methods section of manuscript. PBMCs was co-cultivated with irradiated KL-1 at a ratio of 1:1 and supplemented with IL-2 500 U/ml every 3 days. On Day 14, the absolute number of NK cells was calculated by multiplying the total viable number of cells, as determined by manual counting with a hemacytometer, by the percentage of CD56+CD3- cells as determined by flow cytometry. Results are displayed as a scattergram. The mean number of NK cells expanded is shown as straight line. Although there is a trend towards increased expansion among healthy donors compared to patient donors, this linearity was not preserved and no statistically significant difference is noted between healthy donors and patients with cancer
Supplementary Figure S5 from Ex Vivo Expansion of Highly Cytotoxic Human NK Cells by Cocultivation with Irradiated Tumor Cells for Adoptive Immunotherapy
Authors: Lim Seon Ah , Kim Tae-Jin , Lee Jung Eun , Sonn Chung Hee , Kim Kwanghee , Kim Jiyoung , Choi Jong Gwon , Choi Il-Kyu , Yun Chae-Ok , Kim Jae-Hong , Yee Cassian , Kumar Vinay , Lee Kyung-Mi
Published: April 2023

Supplementary Figure S5 PDF file - 27K, Patient year of birth, disease type, stage and sites of metastasis where applicable, for samples which were evaluated in Figure 6 for KL-1 mediated NK cell expansion are shown
Supplementary Figure 1 from Tumor Suppressor NF2/Merlin Is a Microtubule Stabilizer
Authors: Smole Zlatko , Thoma Claudio R. , Applegate Kathryn T. , Duda Maria , Gutbrodt Katrin L. , Danuser Gaudenz , Krek Wilhelm
Published: April 2023

PDF file - 265K, Variation in control movies and between individual siRNA oligos.
Supplementary Movie S1 from Arkadia Regulates Tumor Metastasis by Modulation of the TGF-β Pathway
Authors: Briones-Orta Marco A. , Levy Laurence , Madsen Chris D. , Das Debipriya , Erker Yigit , Sahai Erik , Hill Caroline S.
Published: April 2023

Supplementary Movie S1 AVI file - 1075K, GFP-labeled parental MDA-MB-231 cells were seeded on top of a layer of HUVEC cells, and images were acquired every 5 min using a Plan apochromat 20x 0.8 objective on a Zeiss LSM 780 confocal microscope. The movie was created using Imaris software (Bitplane)
Supplementary Methods and References from Arkadia Regulates Tumor Metastasis by Modulation of the TGF-β Pathway
Authors: Briones-Orta Marco A. , Levy Laurence , Madsen Chris D. , Das Debipriya , Erker Yigit , Sahai Erik , Hill Caroline S.
Published: April 2023

Supplementary Methods and References PDF File - 125K, Supplementary methods contains lists of siRNAs, primers and antibodies, and methods for genomic sequencing, RNA-sequencing, RT-PCR, qPCR, soft agar and cell cycle analysis, cell spreading and adhesion assays
Supplementary Figure 8 from Cancer-Associated Fibroblasts Expressing CXCL14 Rely upon NOS1-Derived Nitric Oxide Signaling for Their Tumor-Supporting Properties
Authors: Augsten Martin , Sjöberg Elin , Frings Oliver , Vorrink Sabine U. , Frijhoff Jeroen , Olsson Eleonor , Borg Åke , Östman Arne
Published: April 2023

PDF file - 135KB, Recruitment of blood vessels into fibroblast-stimulated prostate and breast tumors.
Supplementary Figure S4 from Arkadia Regulates Tumor Metastasis by Modulation of the TGF-β Pathway
Authors: Briones-Orta Marco A. , Levy Laurence , Madsen Chris D. , Das Debipriya , Erker Yigit , Sahai Erik , Hill Caroline S.
Published: April 2023

Supplementary Figure S4 PDF File - 152K, Molecular characterization of MDA-MB-231 cells stably expressing FLAG-tagged Arkadia C937A
Supplementary Figure 4 from Cancer-Associated Fibroblasts Expressing CXCL14 Rely upon NOS1-Derived Nitric Oxide Signaling for Their Tumor-Supporting Properties
Authors: Augsten Martin , Sjöberg Elin , Frings Oliver , Vorrink Sabine U. , Frijhoff Jeroen , Olsson Eleonor , Borg Åke , Östman Arne
Published: April 2023

PDF file - 42KB, Nos1 is induced upon oxidative stress in NIH3T3 fibroblasts.
Supplementary Figure 3 from Cancer-Associated Fibroblasts Expressing CXCL14 Rely upon NOS1-Derived Nitric Oxide Signaling for Their Tumor-Supporting Properties
Authors: Augsten Martin , Sjöberg Elin , Frings Oliver , Vorrink Sabine U. , Frijhoff Jeroen , Olsson Eleonor , Borg Åke , Östman Arne
Published: April 2023

PDF file - 53KB, Enhanced activation of Hif1α-signaling in CXCL14-fibroblasts.
Supplementary Methods from Neuregulin Autocrine Signaling Promotes Self-Renewal of Breast Tumor-Initiating Cells by Triggering HER2/HER3 Activation
Authors: Lee Cleo Yi-Fang , Lin Yuan , Bratman Scott V. , Feng Weiguo , Kuo Angera H. , Scheeren Ferenc A. , Engreitz Jesse M. , Varma Sushama , West Robert B. , Diehn Maximilian
Published: April 2023

PDF file - 73K
Supplementary Figure Legends from β-Catenin Activation in a Novel Liver Progenitor Cell Type Is Sufficient to Cause Hepatocellular Carcinoma and Hepatoblastoma
Authors: Mokkapati Sharada , Niopek Katharina , Huang Le , Cunniff Kegan J. , Ruteshouser E. Cristy , deCaestecker Mark , Finegold Milton J. , Huff Vicki
Published: April 2023

PDF file - 116KB
Supplementary Figure Legends from Local and Systemic Protumorigenic Effects of Cancer-Associated Fibroblast-Derived GDF15
Authors: Bruzzese Francesca , Hägglöf Christina , Leone Alessandra , Sjöberg Elin , Roca Maria Serena , Kiflemariam Sara , Sjöblom Tobias , Hammarsten Peter , Egevad Lars , Bergh Anders , Östman Arne , Budillon Alfredo , Augsten Martin
Published: April 2023

PDF file - 85KB
Supplementary Figure 5 from Local and Systemic Protumorigenic Effects of Cancer-Associated Fibroblast-Derived GDF15
Authors: Bruzzese Francesca , Hägglöf Christina , Leone Alessandra , Sjöberg Elin , Roca Maria Serena , Kiflemariam Sara , Sjöblom Tobias , Hammarsten Peter , Egevad Lars , Bergh Anders , Östman Arne , Budillon Alfredo , Augsten Martin
Published: April 2023

PDF file - 157KB, Fibroblast-derived GDF15/MIC-1 stimulates cytokine production by LNCaP cells.
Supplementary Figure 1 from Local and Systemic Protumorigenic Effects of Cancer-Associated Fibroblast-Derived GDF15
Authors: Bruzzese Francesca , Hägglöf Christina , Leone Alessandra , Sjöberg Elin , Roca Maria Serena , Kiflemariam Sara , Sjöblom Tobias , Hammarsten Peter , Egevad Lars , Bergh Anders , Östman Arne , Budillon Alfredo , Augsten Martin
Published: April 2023

PDF file - 114KB, GDF15/MIC-1 expression in prostate tumor tissue.
Supplementary Figure Legend from A Preclinical Assay for Chemosensitivity in Multiple Myeloma
Authors: Khin Zayar P. , Ribeiro Maria L.C. , Jacobson Timothy , Hazlehurst Lori , Perez Lia , Baz Rachid , Shain Kenneth , Silva Ariosto S.
Published: April 2023

PDF file - 80K
Supplementary Figure 4 from A Preclinical Assay for Chemosensitivity in Multiple Myeloma
Authors: Khin Zayar P. , Ribeiro Maria L.C. , Jacobson Timothy , Hazlehurst Lori , Perez Lia , Baz Rachid , Shain Kenneth , Silva Ariosto S.
Published: April 2023

PDF file - 67K, The duration of bortezomib activity post-withdrawal.
Supplementary Figure 3 from A Preclinical Assay for Chemosensitivity in Multiple Myeloma
Authors: Khin Zayar P. , Ribeiro Maria L.C. , Jacobson Timothy , Hazlehurst Lori , Perez Lia , Baz Rachid , Shain Kenneth , Silva Ariosto S.
Published: April 2023

PDF file - 126K, The duration of melphalan toxicity post-withdrawal.
Supplementary Table S2 from Amplification of FRS2 and Activation of FGFR/FRS2 Signaling Pathway in High-Grade Liposarcoma
Authors: Zhang Keqiang , Chu Kevin , Wu Xiwei , Gao Hanlin , Wang Jinhui , Yuan Yate-Ching , Loera Sofia , Ho Kimberley , Wang Yafan , Chow Warren , Un Frank , Chu Peiguo , Yen Yun
Published: April 2023

Supplementary Table S2 PDF file 122K, Immunohistochemical staining and FISH results of DDLS
Supplementary Figure 4 from AMPK Activation by Oncogenesis Is Required to Maintain Cancer Cell Proliferation in Astrocytic Tumors
Authors: Ríos Marcos , Foretz Marc , Viollet Benoit , Prieto Angel , Fraga Máximo , Costoya Jose A. , Señarís Rosa
Published: April 2023

PDF file - 48K, Supplemental figure 4. AMPK inhibition reduces tumour growth ratio in a xenograft model.
Supplementary Figure 1 from AMPK Activation by Oncogenesis Is Required to Maintain Cancer Cell Proliferation in Astrocytic Tumors
Authors: Ríos Marcos , Foretz Marc , Viollet Benoit , Prieto Angel , Fraga Máximo , Costoya Jose A. , Señarís Rosa
Published: April 2023

PDF file - 61K, Supplemental figure 1: Characterization of astrocytes with HRasV12 expression and/or Pten deletion.
Supplementary Figures from ATIP3, a Novel Prognostic Marker of Breast Cancer Patient Survival, Limits Cancer Cell Migration and Slows Metastatic Progression by Regulating Microtubule Dynamics
Authors: Molina Angie , Velot Lauriane , Ghouinem Lydia , Abdelkarim Mohamed , Bouchet Benjamin Pierre , Luissint Anny-Claude , Bouhlel Imène , Morel Marina , Sapharikas Elène , Di Tommaso Anne , Honoré Stéphane , Braguer Diane , Gruel Nadège , Vincent-Salomon Anne , Delattre Olivier , Sigal-Zafrani Brigitte , André Fabrice , Terris Benoit , Akhmanova Anna , Di Benedetto Mélanie , Nahmias Clara , Rodrigues-Ferreira Sylvie
Published: April 2023

Supplementary Figures PDF file - 486K, Figure S1. Low levels of ATIP3 associate with decreased overall and relapse-free survival of the patients;Figure S2. Anti-metastatic effects of ATIP3 in vivo; Figure S3. ATIP3 inhibits breast cancer cell proliferation and migration; Figure S4. ATIP3 regulates MT dynamics; Figure S5. Characterization of ATIP3 domains
Movie 6 from ATIP3, a Novel Prognostic Marker of Breast Cancer Patient Survival, Limits Cancer Cell Migration and Slows Metastatic Progression by Regulating Microtubule Dynamics
Authors: Molina Angie , Velot Lauriane , Ghouinem Lydia , Abdelkarim Mohamed , Bouchet Benjamin Pierre , Luissint Anny-Claude , Bouhlel Imène , Morel Marina , Sapharikas Elène , Di Tommaso Anne , Honoré Stéphane , Braguer Diane , Gruel Nadège , Vincent-Salomon Anne , Delattre Olivier , Sigal-Zafrani Brigitte , André Fabrice , Terris Benoit , Akhmanova Anna , Di Benedetto Mélanie , Nahmias Clara , Rodrigues-Ferreira Sylvie
Published: April 2023

Movie 6 AVI file - 5618K, Time-lapse videomicroscopy of EB3-GFP comets in wild type and mCherry-ATIP3 transfected MRC5 cells
Supplementary Figures 1 - 3 from MAPK Kinase 3 Is a Tumor Suppressor with Reduced Copy Number in Breast Cancer
Authors: MacNeil Adam J. , Jiao Shun-Chang , McEachern Lori A. , Yang Yong Jun , Dennis Amanda , Yu Haiming , Xu Zhaolin , Marshall Jean S. , Lin Tong-Jun
Published: April 2023

PDF file - 612K, Supplementary Figure S1. Correlation of genomic loss and mRNA expression in breast cancer patients. Supplementary Figure S2. Generation of stable MDA-MB-468 cell lines expressing MKK3dn or MKK3ca. Supplementary Figure S3. MKK3 signalling inhibits Akt activation in MDA-MB-468 cells.
Movie 1 from ATIP3, a Novel Prognostic Marker of Breast Cancer Patient Survival, Limits Cancer Cell Migration and Slows Metastatic Progression by Regulating Microtubule Dynamics
Authors: Molina Angie , Velot Lauriane , Ghouinem Lydia , Abdelkarim Mohamed , Bouchet Benjamin Pierre , Luissint Anny-Claude , Bouhlel Imène , Morel Marina , Sapharikas Elène , Di Tommaso Anne , Honoré Stéphane , Braguer Diane , Gruel Nadège , Vincent-Salomon Anne , Delattre Olivier , Sigal-Zafrani Brigitte , André Fabrice , Terris Benoit , Akhmanova Anna , Di Benedetto Mélanie , Nahmias Clara , Rodrigues-Ferreira Sylvie
Published: April 2023

Movie 1 AVI file - 2575K, Time-lapse videomicroscopy of wound healing assay using GFP-transfected D3H2LN clone
Supplementary Figure Legend from Parathyroid Hormone–Related Protein Drives a CD11b+Gr1+ Cell–Mediated Positive Feedback Loop to Support Prostate Cancer Growth
Authors: Park Serk In , Lee Changki , Sadler W. David , Koh Amy J. , Jones Jacqueline , Seo Jung Won , Soki Fabiana N. , Cho Sun Wook , Daignault Stephanie D. , McCauley Laurie K.
Published: April 2023

PDF file - 76K
Supplementary Video 2 from Galectin-1 Drives Pancreatic Carcinogenesis through Stroma Remodeling and Hedgehog Signaling Activation
Authors: Martínez-Bosch Neus , Fernández-Barrena Maite G. , Moreno Mireia , Ortiz-Zapater Elena , Munné-Collado Jessica , Iglesias Mar , André Sabine , Gabius Hans-Joachim , Hwang Rosa F. , Poirier Françoise , Navas Carolina , Guerra Carmen , Fernández-Zapico Martin E. , Navarro Pilar
Published: April 2023

AVI file - 3855KB, Supplementary video 2 (Related to Figure 4E). Time lapse video microscopy in PANC-1 cells infected with a Gal1 shRNA (shGal1#1). Frames were collected every 15 min for 12h.
Supplementary Figure 2 from Parathyroid Hormone–Related Protein Drives a CD11b+Gr1+ Cell–Mediated Positive Feedback Loop to Support Prostate Cancer Growth
Authors: Park Serk In , Lee Changki , Sadler W. David , Koh Amy J. , Jones Jacqueline , Seo Jung Won , Soki Fabiana N. , Cho Sun Wook , Daignault Stephanie D. , McCauley Laurie K.
Published: April 2023

PDF file - 5411K, Supplemental Fig. 2 PTHrP promoted tumorigenic function of CD11b+Gr1+ cells.
Supplementary Figure 4 from EGFR-Mediated Chromatin Condensation Protects KRAS-Mutant Cancer Cells against Ionizing Radiation
Authors: Wang Meng , Kern Ashley M. , Hülskötter Marieke , Greninger Patricia , Singh Anurag , Pan Yunfeng , Chowdhury Dipanjan , Krause Mechthild , Baumann Michael , Benes Cyril H. , Efstathiou Jason A. , Settleman Jeff , Willers Henning
Published: April 2023

PDF file - 129KB, Effects of EGFR inhibition on regulation of senescence and apoptosis.
Supplementary Methods, Figures 1-4 from Nitric Oxide–Dependent Downregulation of BRCA1 Expression Promotes Genetic Instability
Authors: Yakovlev Vasily A.
Published: April 2023

PDF file - 2.9MB, Additional Material and Methods: Fluorescence-based DSB Repair Assay, Flow Cytometry; Figure S1: Measuring of HRR level; Figure S2: Labeling and sorting with anti-mouse F4/80Ab; Figure S3: Level of BRCA1 and RBL2 after different doses of SNAP; Figure S4: Expression of I-SceI endonuclease after Ad-SceI-NG infection
Supplementary Figure 4 from Inhibition of SRC Corrects GM-CSF Hypersensitivity That Underlies Juvenile Myelomonocytic Leukemia
Authors: Bunda Severa , Kang Michelle W. , Sybingco Stephanie S. , Weng Julie , Favre Helene , Shin Danielle H. , Irwin Meredith S. , Loh Mignon L. , Ohh Michael
Published: April 2023

PDF file - 269K, Dasatinib inhibits GM-CSF-induced phosphorylation of ERK in primary JMML cells from patients with CBL, NF1 and PTPN11 mutation
Supplementary Figure Legend from Targeting the Deregulated Spliceosome Core Machinery in Cancer Cells Triggers mTOR Blockade and Autophagy
Authors: Quidville Virginie , Alsafadi Samar , Goubar Aïcha , Commo Frédéric , Scott Véronique , Pioche-Durieu Catherine , Girault Isabelle , Baconnais Sonia , Le Cam Eric , Lazar Vladimir , Delaloge Suzette , Saghatchian Mahasti , Pautier Patricia , Morice Philippe , Dessen Philippe , Vagner Stéphan , André Fabrice
Published: April 2023

PDF file - 100K
Supplementary Methods from RNAi-Mediated Silencing of Myc Transcription Inhibits Stem-like Cell Maintenance and Tumorigenicity in Prostate Cancer
Authors: Civenni Gianluca , Malek Anastasia , Albino Domenico , Garcia-Escudero Ramon , Napoli Sara , Di Marco Stefano , Pinton Sandra , Sarti Manuela , Carbone Giuseppina M. , Catapano Carlo V.
Published: April 2023

PDF file - 94K
Supplementary Figure Legend from RNAi-Mediated Silencing of Myc Transcription Inhibits Stem-like Cell Maintenance and Tumorigenicity in Prostate Cancer
Authors: Civenni Gianluca , Malek Anastasia , Albino Domenico , Garcia-Escudero Ramon , Napoli Sara , Di Marco Stefano , Pinton Sandra , Sarti Manuela , Carbone Giuseppina M. , Catapano Carlo V.
Published: April 2023

PDF file - 73K
Supplementary Figure 6 from RNAi-Mediated Silencing of Myc Transcription Inhibits Stem-like Cell Maintenance and Tumorigenicity in Prostate Cancer
Authors: Civenni Gianluca , Malek Anastasia , Albino Domenico , Garcia-Escudero Ramon , Napoli Sara , Di Marco Stefano , Pinton Sandra , Sarti Manuela , Carbone Giuseppina M. , Catapano Carlo V.
Published: April 2023

PDF file - 22K, Expression of Myc in normal prostate epithelial cells (PrECs) and ESE3kd-PrECs determined by qRT-PCR.
Supplementary Figure 2 from Loss of TGF-β Adaptor β2SP Activates Notch Signaling and SOX9 Expression in Esophageal Adenocarcinoma
Authors: Song Shumei , Maru Dipen M. , Ajani Jaffer A. , Chan Chia-Hsin , Honjo Soichiro , Lin Hui-Kuan , Correa Arlene , Hofstetter Wayne L. , Davila Marta , Stroehlein John , Mishra Lopa
Published: April 2023

PDF file - 6469K, Activated Notch 1 receptor (ICN1) and stem cell markers were increased in xenograft mouse tumor tissues with knockdown β2SP. Expression of ICN1, ALDH-1, Oct3/4 and Lgr5 were determined by immunohistochemistry as described in Materials & Methods.
Supplementary Figure Legends from CLPTM1L Promotes Growth and Enhances Aneuploidy in Pancreatic Cancer Cells
Authors: Jia Jinping , Bosley Allen D. , Thompson Abbey , Hoskins Jason W. , Cheuk Adam , Collins Irene , Parikh Hemang , Xiao Zhen , Ylaya Kris , Dzyadyk Marta , Cozen Wendy , Hernandez Brenda Y. , Lynch Charles F. , Loncarek Jadranka , Altekruse Sean F. , Zhang Lizhi , Westlake Christopher J. , Factor Valentina M. , Thorgeirsson Snorri , Bamlet William R. , Hewitt Stephen M. , Petersen Gloria M. , Andresson Thorkell , Amundadottir Laufey T.
Published: April 2023

PDF file - 46KB
Supplementary Figure 6 from CLPTM1L Promotes Growth and Enhances Aneuploidy in Pancreatic Cancer Cells
Authors: Jia Jinping , Bosley Allen D. , Thompson Abbey , Hoskins Jason W. , Cheuk Adam , Collins Irene , Parikh Hemang , Xiao Zhen , Ylaya Kris , Dzyadyk Marta , Cozen Wendy , Hernandez Brenda Y. , Lynch Charles F. , Loncarek Jadranka , Altekruse Sean F. , Zhang Lizhi , Westlake Christopher J. , Factor Valentina M. , Thorgeirsson Snorri , Bamlet William R. , Hewitt Stephen M. , Petersen Gloria M. , Andresson Thorkell , Amundadottir Laufey T.
Published: April 2023

PDF file - 76KB, CLPTM1L protein levels are enhanced in pancreatic adenocarcinomas.
Supplementary Figure 5 from STC1 Expression By Cancer-Associated Fibroblasts Drives Metastasis of Colorectal Cancer
Authors: Peña Cristina , Céspedes María Virtudes , Lindh Maja Bradic , Kiflemariam Sara , Mezheyeuski Artur , Edqvist Per-Henrik , Hägglöf Christina , Birgisson Helgi , Bojmar Linda , Jirström Karin , Sandström Per , Olsson Eleonor , Veerla Srinivas , Gallardo Alberto , Sjöblom Tobias , Chang Andy C.-M. , Reddel Roger R. , Mangues Ramón , Augsten Martin , Östman Arne
Published: April 2023

PDF file - 938K, Analyses of relationship between size of primary tumor and metastases.
Supplementary Table 1 from ST6Gal-I Protein Expression Is Upregulated in Human Epithelial Tumors and Correlates with Stem Cell Markers in Normal Tissues and Colon Cancer Cell Lines
Authors: Swindall Amanda F. , Londoño-Joshi Angelina I. , Schultz Matthew J. , Fineberg Naomi , Buchsbaum Donald J. , Bellis Susan L.
Published: April 2023

PDF file - 22K, Patient demographics and pathological diagnosis for colon tumor samples
Supplementary Figure 2 from ST6Gal-I Protein Expression Is Upregulated in Human Epithelial Tumors and Correlates with Stem Cell Markers in Normal Tissues and Colon Cancer Cell Lines
Authors: Swindall Amanda F. , Londoño-Joshi Angelina I. , Schultz Matthew J. , Fineberg Naomi , Buchsbaum Donald J. , Bellis Susan L.
Published: April 2023

PDF file - 187K, Negative controls for ST6Gal-I staining of tissue sections
Supplementary Figure 2 from Anti-CD20 Antibody Promotes Cancer Escape via Enrichment of Tumor-Evoked Regulatory B Cells Expressing Low Levels of CD20 and CD137L
Authors: Bodogai Monica , Lee Chang Catalina , Wejksza Katarzyna , Lai Jinping , Merino Maria , Wersto Robert P. , Gress Ronald E. , Chan Andrew C. , Hesdorffer Charles , Biragyn Arya
Published: April 2023

PDF file - 206K, Regulatory activity is mostly retained in human tBregs expressing low levels of CD20
Supplementary Table S2 from Genetic Amplification of the NOTCH Modulator LNX2 Upregulates the WNT/β-Catenin Pathway in Colorectal Cancer
Authors: Camps Jordi , Pitt Jason J. , Emons Georg , Hummon Amanda B. , Case Chanelle M. , Grade Marian , Jones Tamara L. , Nguyen Quang T. , Ghadimi B. Michael , Beissbarth Tim , Difilippantonio Michael J. , Caplen Natasha J. , Ried Thomas
Published: April 2023

Supplementary Table S2 PDF file - 589K, List of siRNAs
Supplementary Figure 3-1 from Erlotinib Prolongs Survival in Pancreatic Cancer by Blocking Gemcitabine-Induced MAPK Signals
Authors: Miyabayashi Koji , Ijichi Hideaki , Mohri Dai , Tada Motohisa , Yamamoto Keisuke , Asaoka Yoshinari , Ikenoue Tsuneo , Tateishi Keisuke , Nakai Yousuke , Isayama Hiroyuki , Morishita Yasuyuki , Omata Masao , Moses Harold L. , Koike Kazuhiko
Published: April 2023

Supplementary Figure 3-1 PDF file - 354K, Gemcitabine-induced expression of EGFR ligands was dependent on active MAPK signaling in the PDAC cells
Supplementary Table 1 from xCT Inhibition Depletes CD44v-Expressing Tumor Cells That Are Resistant to EGFR-Targeted Therapy in Head and Neck Squamous Cell Carcinoma
Authors: Yoshikawa Momoko , Tsuchihashi Kenji , Ishimoto Takatsugu , Yae Toshifumi , Motohara Takeshi , Sugihara Eiji , Onishi Nobuyuki , Masuko Takashi , Yoshizawa Kunio , Kawashiri Shuichi , Mukai Makio , Asoda Seiji , Kawana Hiromasa , Nakagawa Taneaki , Saya Hideyuki , Nagano Osamu
Published: April 2023

PDF file - 79K, Clinicopathological characteristics of HNSCC patients in Figure 1.
Supplementary Figure 2 from Deficiency of Phospholipase A2 Group 7 Decreases Intestinal Polyposis and Colon Tumorigenesis in ApcMin/+ Mice
Authors: Xu Changxin , Reichert Ethan C. , Nakano Tomoyuki , Lohse Mariah , Gardner Alison A. , Revelo Mónica P. , Topham Matthew K. , Stafforini Diana M.
Published: April 2023

PDF file - 144K, PKC inhibition does not affect cPAF-induced de-phosphorylation of pAkt473
Supplementary Figure 1 from The HSP90 Inhibitor Ganetespib Synergizes with the MET Kinase Inhibitor Crizotinib in both Crizotinib-Sensitive and -Resistant MET-Driven Tumor Models
Authors: Miyajima Naoto , Tsutsumi Shinji , Sourbier Carole , Beebe Kristin , Mollapour Mehdi , Rivas Candy , Yoshida Soichiro , Trepel Jane B. , Huang Ying , Tatokoro Manabu , Shinohara Nobuo , Nonomura Katsuya , Neckers Len
Published: April 2023

PDF file - 172K, Proteasome inhibition reverses the impact of GA on phospho-MET and total MET protein expression.
Supplementary Figures 1 - 3, Tables 1 - 3 from Targeting Mitochondrial Oxidative Metabolism in Melanoma Causes Metabolic Compensation through Glucose and Glutamine Utilization
Authors: Lim Ji-Hong , Luo Chi , Vazquez Francisca , Puigserver Pere
Published: April 2023

PDF file - 344KB, Supplementary Figure 1. A, Levels of PGC1alpha target genes in PGC1α-suppressed tumors. Supplementary Figure 2. HIF-1alpha protein levels and glycolytic target genes in PGC1α negative and positive melanoma cells after exposure to hypoxia or oxidative stress. Supplementary Figure 3. A, Effects of doxycycline treatment on the expression of HIF-1α target glycolytic genes. Supplementary Table 1. Gene sets of genes induced under hypoxia. Supplementary Table 2. shRNA sequences. Supplementary Table 3. Sequence of primers for quantitative RT-PCR.
Supplementary Figure 3 from Distinguishing between Benign and Malignant Melanocytic Nevi by In Vivo Multiphoton Microscopy
Authors: Balu Mihaela , Kelly Kristen M. , Zachary Christopher B. , Harris Ronald M. , Krasieva Tatiana B. , König Karsten , Durkin Anthony J. , Tromberg Bruce J.
Published: April 2023

PDF file - 178KB, Melanoma. (a) Clinical image. (b) Histology image of the lesion showing pagetoid spread in the upper epidermal layers (arrows). (c-e) MPM images of epidermal layers showing advanced melanocytic dendrites (red arrows) and pleomorphic cells/pagetoid spread (yellow arrows) in upper epidermal layers at depths of 40 microm (c), 45 microm, (d) and 50 microm (e). Scale bar is 20 microm.
Supplementary Tables 1 - 4 from Distinct Effects of Ligand-Induced PDGFRα and PDGFRβ Signaling in the Human Rhabdomyosarcoma Tumor Cell and Stroma Cell Compartments
Authors: Ehnman Monika , Missiaglia Edoardo , Folestad Erika , Selfe Joanna , Strell Carina , Thway Khin , Brodin Bertha , Pietras Kristian , Shipley Janet , Östman Arne , Eriksson Ulf
Published: April 2023

PDF file - 166K, Gene list of the top 30 genes correlating with PDGF-C (top) and PDGF-D (bottom) gene expression in human RMS (S1); PDGF-C and PDGF-D expression levels in RMS cell lines. Values reported represent the log-transformed intensity of probes (Affymetrix microarray) measuring the expression of PDGF-C and PDGF-D genes (S2); RMS cell lines used in the functional experiments (S3); Overview of qRT-PCR primers (S4).
Supplementary Figure 6 from Distinct Effects of Ligand-Induced PDGFRα and PDGFRβ Signaling in the Human Rhabdomyosarcoma Tumor Cell and Stroma Cell Compartments
Authors: Ehnman Monika , Missiaglia Edoardo , Folestad Erika , Selfe Joanna , Strell Carina , Thway Khin , Brodin Bertha , Pietras Kristian , Shipley Janet , Östman Arne , Eriksson Ulf
Published: April 2023

PDF file - 669K, CP-673,451 treatment does not affect growth of tumors derived from the RMS cell line. A, PDGFRβ expression in infiltrating stroma. B, RMS tumor growth in response to CP-673,451 or vehicle (n≥9 mice/group).
Supplementary Figure 5 from Distinct Effects of Ligand-Induced PDGFRα and PDGFRβ Signaling in the Human Rhabdomyosarcoma Tumor Cell and Stroma Cell Compartments
Authors: Ehnman Monika , Missiaglia Edoardo , Folestad Erika , Selfe Joanna , Strell Carina , Thway Khin , Brodin Bertha , Pietras Kristian , Shipley Janet , Östman Arne , Eriksson Ulf
Published: April 2023

PDF file - 25K, Human PDGFRβ ligands can activate mouse PDGFRβ. Immunoblotting of pPDGFRβ and total PDGFRβ in C2C12 cells after ligand stimulation as indicated.
Supplementary Figure 2 from Distinct Effects of Ligand-Induced PDGFRα and PDGFRβ Signaling in the Human Rhabdomyosarcoma Tumor Cell and Stroma Cell Compartments
Authors: Ehnman Monika , Missiaglia Edoardo , Folestad Erika , Selfe Joanna , Strell Carina , Thway Khin , Brodin Bertha , Pietras Kristian , Shipley Janet , Östman Arne , Eriksson Ulf
Published: April 2023

PDF file - 46K, Gene set enrichment analysis associates PDGF-D expression with genes involved in ECM organization, leukocyte transendothelial migration and cell adhesion in human RMS tumors. A, biological processes associated with genes expressed in high PDGF-D expressing tumors compared to low PDGF-D expressing tumors, based on GO annotations. The first 17 categories that reached a p-value <0.01 are shown. B, pathways associated with genes expressed in high PDGF-D expressing tumors compared to low PDGF-D expressing tumors, using KEGG annotations. The first 11 categories that reached a p-value <0.01 are shown.
Supplementary Figures 1 - 7 from Interleukin 21–Induced Granzyme B–Expressing B Cells Infiltrate Tumors and Regulate T Cells
Authors: Lindner Stefanie , Dahlke Karen , Sontheimer Kai , Hagn Magdalena , Kaltenmeier Christof , Barth Thomas F.E. , Beyer Thamara , Reister Frank , Fabricius Dorit , Lotfi Ramin , Lunov Oleg , Nienhaus G. Ulrich , Simmet Thomas , Kreienberg Rolf , Möller Peter , Schrezenmeier Hubert , Jahrsdörfer Bernd
Published: April 2023

PDF file - 182K, Supplemental Figure 1. B cells activated with IL-21 and anti-BCR secrete enzymatically active granzyme B. Supplemental Figure 2. Interleukin 21 in the absence of B cells does not suppress T cell proliferation. Supplemental Figure 3. GrB-secreting B cells do not induce apoptosis in T cells. Supplemental Figure 4. IL-10, CD25 and IDO are expressed on IL-21-induced GrB+ Breg, but not on GrB- B cells. Supplemental Figure 5. IL-2 retitration has no significant effect on the suppression of CD4+ T cell proliferation by GrB-secreting B cells. Supplemental Figure 6. IL-21-induced GrB secretion by B cells depends on TLR7 and TLR9 signaling. Supplemental Figure 7. B cells in the microenvironment of solid tumors sporadically express IL-10.
Supplementary Figure 1 from Distinct Effects of Ligand-Induced PDGFRα and PDGFRβ Signaling in the Human Rhabdomyosarcoma Tumor Cell and Stroma Cell Compartments
Authors: Ehnman Monika , Missiaglia Edoardo , Folestad Erika , Selfe Joanna , Strell Carina , Thway Khin , Brodin Bertha , Pietras Kristian , Shipley Janet , Östman Arne , Eriksson Ulf
Published: April 2023

PDF file - 882K, Antibodies directed against human full-length PDGF-CC and PDGF-DD recognize their target proteins. Antibody specificity was evaluated in paraffin-embedded COS-1 cell pellets after transient transfection with plasmid constructs expressing PDGF proteins as indicated. The transfection efficiency was estimated to be approximately 40%. Additional analyses indicated that the PDGF-CC antibody displayed some crossreactivity with the processed form of PDGF-DD (data not shown).
Supplementary Table 1 from Cell Surface Receptor FPR2 Promotes Antitumor Host Defense by Limiting M2 Polarization of Macrophages
Authors: Liu Ying , Chen Keqiang , Wang Chunyan , Gong Wanghua , Yoshimura Teizo , Liu Mingyong , Wang Ji Ming
Published: April 2023

PDF file - 68K, PCR primers used in the study
Supplementary Figure 5 from An Essential Requirement for the SCAP/SREBP Signaling Axis to Protect Cancer Cells from Lipotoxicity
Authors: Williams Kevin J. , Argus Joseph P. , Zhu Yue , Wilks Moses Q. , Marbois Beth N. , York Autumn G. , Kidani Yoko , Pourzia Alexandra L. , Akhavan David , Lisiero Dominique N. , Komisopoulou Evangelia , Henkin Amy H. , Soto Horacio , Chamberlain Brian T. , Vergnes Laurent , Jung Michael E. , Torres Jorge Z. , Liau Linda M. , Christofk Heather R. , Prins Robert M. , Mischel Paul S. , Reue Karen , Graeber Thomas G. , Bensinger Steven J.
Published: April 2023

PDF File - 90K, Loss of SREBP signaling results in the uncoupling of saturated fatty acid biosynthesis from desaturase activity.
Supplementary Figure 4 from Cell Surface Receptor FPR2 Promotes Antitumor Host Defense by Limiting M2 Polarization of Macrophages
Authors: Liu Ying , Chen Keqiang , Wang Chunyan , Gong Wanghua , Yoshimura Teizo , Liu Mingyong , Wang Ji Ming
Published: April 2023

PDF file - 76K, Chemokines in the supernatant of tumor cell lines
Supplementary Figure Legend from Chemotherapy Acts as an Adjuvant to Convert the Tumor Microenvironment into a Highly Permissive State for Vaccination-Induced Antitumor Immunity
Authors: Kang Tae Heung , Mao Chih-Ping , Lee Sung Yong , Chen Alexander , Lee Ji-Hyun , Kim Tae Woo , Alvarez Ronald D. , Roden Richard B.S. , Pardoll Drew , Hung Chien-Fu , Wu T.-C.
Published: April 2023

PDF file - 60K
Supplementary Figures 1 - 6, Tables 1 - 7 from Biallelic DICER1 Mutations in Sporadic Pleuropulmonary Blastoma
Authors: Seki Masafumi , Yoshida Kenichi , Shiraishi Yuichi , Shimamura Teppei , Sato Yusuke , Nishimura Riki , Okuno Yusuke , Chiba Kenichi , Tanaka Hiroko , Kato Keisuke , Kato Motohiro , Hanada Ryoji , Nomura Yuko , Park Myoung-Ja , Ishida Toshiaki , Oka Akira , Igarashi Takashi , Miyano Satoru , Hayashi Yasuhide , Ogawa Seishi , Takita Junko
Published: April 2023

PDF file - 1805KB, Supplementary Table S1. List of primers used for validation of somatic mutations detected by whole-exome sequencing. Supplementary Table S2. Primers for DICER1 sequencing of all coding exons. Supplementary Table S3. Primers for DICER1 sequencing of all coding exons in paraffin embedded samples. Supplementary Table S4. Primers for TP53, UBA2, PDCD2L, CTNNB1, and GPR182. Supplementary Table S5. List of mutated genes detected by whole-exome sequencing. Supplementary Table S6. Allele frequency of DICER1 mutations in cases with unknown somatic status. Supplementary Table S7. Recurrent mutations detected by whole-exome sequencing. Supplementary Figure S1. Analyzing processes using Genomon. Supplementary Figure S2. Mean coverage of whole-exome sequencing in primary tumor, relapse tumor, and control samples. Supplementary Figure S3. Mean coverage of whole exome sequencing with GC contents in primary tumor, relapse tumor and control samples. Supplementary Figure S4. Detected mutations of DICER1 by Sanger sequencing. Supplementary Figure S5. Distribution of genetic lesions with 14 samples in PPB cases. Supplementary Figure S6. Common amplification lesion at 19q13.11.
Supplementary Figure Legend from The Major Reverse Transcriptase–Incompetent Splice Variant of the Human Telomerase Protein Inhibits Telomerase Activity but Protects from Apoptosis
Authors: Listerman Imke , Sun Jie , Gazzaniga Francesca S. , Lukas Jason L. , Blackburn Elizabeth H.
Published: April 2023

PDF file - 45K
Supplementary Figure 4 from Genetic and Pharmacologic Inhibition of mTORC1 Promotes EMT by a TGF-β–Independent Mechanism
Authors: Mikaelian Ivan , Malek Mouhannad , Gadet Rudy , Viallet Jean , Garcia Amandine , Girard-Gagnepain Anaïs , Hesling Cédric , Gillet Germain , Gonzalo Philippe , Rimokh Ruth , Billaud Marc
Published: April 2023

PDF file - 1195K, Supplementary Figure 4: RPTOR and mTOR silencing impair S6K phosphorylation.
Supplementary Figure 1 from Genetic and Pharmacologic Inhibition of mTORC1 Promotes EMT by a TGF-β–Independent Mechanism
Authors: Mikaelian Ivan , Malek Mouhannad , Gadet Rudy , Viallet Jean , Garcia Amandine , Girard-Gagnepain Anaïs , Hesling Cédric , Gillet Germain , Gonzalo Philippe , Rimokh Ruth , Billaud Marc
Published: April 2023

PDF file - 441K, Supplementary Figure 1: SiRNA screening procedure.
Supplementary Figure 3 from HNRNPAB Induces Epithelial–Mesenchymal Transition and Promotes Metastasis of Hepatocellular Carcinoma by Transcriptionally Activating SNAIL
Authors: Zhou Zheng-Jun , Dai Zhi , Zhou Shao-Lai , Hu Zhi-Qiang , Chen Qing , Zhao Yi-Ming , Shi Ying-Hong , Gao Qiang , Wu Wei-Zhong , Qiu Shuang-Jian , Zhou Jian , Fan Jia
Published: April 2023

PDF file - 844K, Supplementary Figure S3. Snail is critical for hnRNPAB-dependent regulation of E-cadherin expression.
Suppl Fig. S4 from Neuromedin U: A Candidate Biomarker and Therapeutic Target to Predict and Overcome Resistance to HER-Tyrosine Kinase Inhibitors
Authors: Rani Sweta , Corcoran Claire , Shiels Liam , Germano Serena , Breslin Susan , Madden Stephen , McDermott Martina S. , Browne Brigid C. , O'Donovan Norma , Crown John , Gogarty Martina , Byrne Annette T. , O'Driscoll Lorraine
Published: April 2023

Suppl Fig. S4
Supplementary Figure 1 from ΔNp63 Promotes Pediatric Neuroblastoma and Osteosarcoma by Regulating Tumor Angiogenesis
Authors: Bid Hemant K. , Roberts Ryan D. , Cam Maren , Audino Anthony , Kurmasheva Raushan T. , Lin Jiayuh , Houghton Peter J. , Cam Hakan
Published: April 2023

PDF file - 158K, mRNA expression analysis of deltaNp63 isoforms in Childhood Tumors.
Supplementary Tables 1 - 4 from CHD7 Expression Predicts Survival Outcomes in Patients with Resected Pancreatic Cancer
Authors: Colbert Lauren E. , Petrova Aleksandra V. , Fisher Sarah B. , Pantazides Brooke G. , Madden Matthew Z. , Hardy Claire W. , Warren Matthew D. , Pan Yunfeng , Nagaraju Ganji P. , Liu Elaine A. , Saka Burcu , Hall William A. , Shelton Joseph W. , Gandhi Khanjan , Pauly Rini , Kowalski Jeanne , Kooby David A. , El-Rayes Bassel F. , Staley Charles A. , Adsay N. Volkan , Curran Walter J. , Landry Jerome C. , Maithel Shishir K. , Yu David S.
Published: April 2023

XLS file - 675KB, Full Results of Primary Gemcitabine Sensitivity Screen (S1). Known DNA Damage Response Genes Identified as Hits in Gemcitabine Sensitivity Screen (S2). Dysregulation, Differential Expression, and Literature RNAi Cross-Reference for Known DDR Genes and Select Hits (S3). Selected Top 15% of Gemcitabine Sensitivity Genes Tested on Secondary Screen (S4).
Supplementary Figure Legends from Mislocalization of the Cell Polarity Protein Scribble Promotes Mammary Tumorigenesis and Is Associated with Basal Breast Cancer
Authors: Feigin Michael E. , Akshinthala S. Dipikaa , Araki Kiyomi , Rosenberg Avi Z. , Muthuswamy Lakshmi B. , Martin Bernard , Lehmann Brian D. , Berman Hal K. , Pietenpol Jennifer A. , Cardiff Robert D. , Muthuswamy Senthil K.
Published: April 2023

PDF file - 68K
Supplementary Figure Legends from NADPH Oxidase NOX4 Supports Renal Tumorigenesis by Promoting the Expression and Nuclear Accumulation of HIF2α
Authors: Gregg Jennifer L. , Turner Robert M. , Chang Guimin , Joshi Disha , Zhan Ye , Chen Li , Maranchie Jodi K.
Published: April 2023

PDF file - 42K
Supplementary Figure 3 from NADPH Oxidase NOX4 Supports Renal Tumorigenesis by Promoting the Expression and Nuclear Accumulation of HIF2α
Authors: Gregg Jennifer L. , Turner Robert M. , Chang Guimin , Joshi Disha , Zhan Ye , Chen Li , Maranchie Jodi K.
Published: April 2023

PDF file - 98K, Supplemental Figure 3. Lucigenin chemiluminescence assay for superoxide detection performed as described in materials and methods on a) isolated membrane fractions from parental 786-0, RCC4 and Caki-1 cells or isolated cell fractions from 786-0 (b) or RCC4 (c) cells. RLU: relative light units.
Supplementary Figure 3 from Low PIP4K2B Expression in Human Breast Tumors Correlates with Reduced Patient Survival: A Role for PIP4K2B in the Regulation of E-Cadherin Expression
Authors: Keune Willem-Jan , Sims Andrew H. , Jones David R. , Bultsma Yvette , Lynch James T. , Jirström Karin , Landberg Goran , Divecha Nullin
Published: April 2023

PDF file - 274K, A. Expression profiles from 17 data sets representing 2999 tumors were extracted, normalised and hierarchically clustered according to tumour subtype. The heat map shows the relative transcript expression of genes in order (named on the right) along chromosome surrounding the ERBB2 gene. The ERBB2 and PIP4K2B are labelled in red. B. ACGH array data from the Chin et al study are shown for genes in order on chromosome 17 surrounding the ERBB2 gene. ERBB2 and PIP4K2B are marked in red on the right side.
Supplementary Figure 3 from Pirfenidone Inhibits Pancreatic Cancer Desmoplasia by Regulating Stellate Cells
Authors: Kozono Shingo , Ohuchida Kenoki , Eguchi Daiki , Ikenaga Naoki , Fujiwara Kenji , Cui Lin , Mizumoto Kazuhiro , Tanaka Masao
Published: April 2023

PDF file - 1482K, Supplementary Figure 3: A. Representative photographs showing histological evaluation of desmoplastic activity on orthotopic pancreatic cancer mouse models. B. Evaluation of the PCNA index (%). C. Representative photographs showing nodules of liver metastasis on the surface of the liver.
Supplementary Figure 2 from Pirfenidone Inhibits Pancreatic Cancer Desmoplasia by Regulating Stellate Cells
Authors: Kozono Shingo , Ohuchida Kenoki , Eguchi Daiki , Ikenaga Naoki , Fujiwara Kenji , Cui Lin , Mizumoto Kazuhiro , Tanaka Masao
Published: April 2023

PDF file - 211K, Supplementary Figure 2: Representative photographs showing histological evaluation of Sirius red positive area on subcutaneous pancreatic cancer mouse models.
Supplementary Table 1 from USP22 Regulates Oncogenic Signaling Pathways to Drive Lethal Cancer Progression
Authors: Schrecengost Randy S. , Dean Jeffry L. , Goodwin Jonathan F. , Schiewer Matthew J. , Urban Mark W. , Stanek Timothy J. , Sussman Robyn T. , Hicks Jessica L. , Birbe Ruth C. , Draganova-Tacheva Rossitza A. , Visakorpi Tapio , DeMarzo Angelo M. , McMahon Steven B. , Knudsen Karen E.
Published: April 2023

PDF file - 50K, Primer sequences used in manuscript.
Supplementary Figure 5 from Trask Loss Enhances Tumorigenic Growth by Liberating Integrin Signaling and Growth Factor Receptor Cross-Talk in Unanchored Cells
Authors: Spassov Danislav S. , Wong Ching Hang , Wong Sunny Y. , Reiter Jeremy F. , Moasser Mark M.
Published: April 2023

PDF file - 1099K, p-Trask immunostain of wounded mouse skin
Supplementary Table 1 from Endocrine Fibroblast Growth Factor FGF19 Promotes Prostate Cancer Progression
Authors: Feng Shu , Dakhova Olga , Creighton Chad J. , Ittmann Michael
Published: April 2023

PDF file - 42KB, Primers used for quantitative RT-PCR and conventional RT-PCR.
Supplementary Methods, Figure Legends, and Tables 1 - 5 from Downregulation of the Novel Tumor Suppressor DIRAS1 Predicts Poor Prognosis in Esophageal Squamous Cell Carcinoma
Authors: Zhu Ying-Hui , Fu Li , Chen Leilei , Qin Yan-Ru , Liu Haibo , Xie Fajun , Zeng Tingting , Dong Sui-Sui , Li Jiangchao , Li Yan , Dai Yongdong , Xie Dan , Guan Xin-Yuan
Published: April 2023

PDF file - 142K
Supplementary Methods from Redox Modulation of Adjacent Thiols in VLA-4 by AS101 Converts Myeloid Leukemia Cells from a Drug-Resistant to Drug-Sensitive State
Authors: Layani-Bazar Adi , Skornick Itai , Berrebi Alain , Pauker Maor H. , Noy Elad , Silberman Alon , Albeck Michael , Longo Dan L. , Kalechman Yona , Sredni Benjamin
Published: April 2023

PDF file - 129K
Supplementary Figure Legend from A Circadian Clock Transcription Model for the Personalization of Cancer Chronotherapy
Authors: Li Xiao-Mei , Mohammad-Djafari Ali , Dumitru Mircea , Dulong Sandrine , Filipski Elisabeth , Siffroi-Fernandez Sandrine , Mteyrek Ali , Scaglione Francesco , Guettier Catherine , Delaunay Franck , Lévi Francis
Published: April 2023

PDF file - 110K
Supplementary Figure 2 from Redox Modulation of Adjacent Thiols in VLA-4 by AS101 Converts Myeloid Leukemia Cells from a Drug-Resistant to Drug-Sensitive State
Authors: Layani-Bazar Adi , Skornick Itai , Berrebi Alain , Pauker Maor H. , Noy Elad , Silberman Alon , Albeck Michael , Longo Dan L. , Kalechman Yona , Sredni Benjamin
Published: April 2023

PDF file - 766K, Fig. S2: Chemoresistance of myelomonocytic leukemia cells induced by BM Stromal cells is abrogated by AS101.
Supplementary Figures 1 - 4 from Targeting XRCC1 Deficiency in Breast Cancer for Personalized Therapy
Authors: Sultana Rebeka , Abdel-Fatah Tarek , Abbotts Rachel , Hawkes Claire , Albarakati Nada , Seedhouse Claire , Ball Graham , Chan Stephen , Rakha Emad A. , Ellis Ian O. , Madhusudan Srinivasan
Published: April 2023

PDF file - 322K, Supplemental Figure 1. Disease free survival (DFS) and distant metastasis free survival (DMFS) in breast cancer whole cohort (A), Lymph node negative (B) and lymphnode positive (C). Supplemental Figure 2. Disease free survival (DFS) and distant metastasis free survival (DMFS) in breast cancerlow risk, no adjuvant therapy (A), high risk, received endocrine therapy (B) and high risk, received CMF chemotherapy (C). Supplemental Figure 3. Disease free survival (DFS) and distant metastasis free survival (DMFS) in breast cancerER negative tumours (A), Triple negative tumours (B). Supplemental Figure 4. Clonogenic survival assay (A), Annexin-V FITC assay (B).
Supplementary Figures 1 - 2 from G Protein–Coupled Receptor Kinase GRK5 Phosphorylates Moesin and Regulates Metastasis in Prostate Cancer
Authors: Chakraborty Prabir Kumar , Zhang Yushan , Coomes Alexandra S. , Kim Wan-Ju , Stupay Rachel , Lynch Lauren D. , Atkinson Tamieka , Kim Jae I. , Nie Zhongzhen , Daaka Yehia
Published: April 2023

PDF file - 31K, Figure S1. GRK5 phosphorylates non-GPCR substrates. Figure S2. Moesin regulates migration and invasion of PCa cells.
Supplementary Figure 5 from De Novo Design of a Tumor-Penetrating Peptide
Authors: Alberici Luca , Roth Lise , Sugahara Kazuki N. , Agemy Lilach , Kotamraju Venkata R. , Teesalu Tambet , Bordignon Claudio , Traversari Catia , Rizzardi Gian-Paolo , Ruoslahti Erkki
Published: April 2023

PDF file - 590K, iNGR penetrates into extravascular tumor tissue
Supplementary Methods, Figures 1 - 7 from HER2 Drives Luminal Breast Cancer Stem Cells in the Absence of HER2 Amplification: Implications for Efficacy of Adjuvant Trastuzumab
Authors: Ithimakin Suthinee , Day Kathleen C. , Malik Fayaz , Zen Qin , Dawsey Scott J. , Bersano-Begey Tom F. , Quraishi Ahmed A. , Ignatoski Kathleen Woods , Daignault Stephanie , Davis April , Hall Christopher L. , Palanisamy Nallasivam , Heath Amber N. , Tawakkol Nader , Luther Tahra K. , Clouthier Shawn G. , Chadwick Whitney A. , Day Mark L. , Kleer Celina G. , Thomas Dafydd G. , Hayes Daniel F. , Korkaya Hasan , Wicha Max S.
Published: April 2023

PDF file - 491K, Supplementary Figure 3. Effect of trastazumab on stem cell marker expression. Supplementary Figure 2. Trastuzumab inhibits tertiary tumorsphere formation in luminal cell lines. Supplementary Figure 1. Representative FACS analysis demonstrating an overlap between HER2 expression and ALDH activity. Supplementary Figure 4. Trastuzumab treatment or HER2 gene knockdown reduces tumorsphere formation of MCF7 cells. Supplementary Figure 5. Rank mediated upreglation of HER2 expression in MCF7 cells. Supplementary Figure 6. Elevated HER2 expression in bone metastasis compared to matched primary luminal tumors is not due to HER2 gene amplification. Supplemental Figure 7. No significant differences in HER2 protein expression were found in matched primary tumors and bone metastasis in women with HER-positive breast cancer.
Supplementary Table 1 from Transcriptional Profiling of Melanoma Sentinel Nodes Identify Patients with Poor Outcome and Reveal an Association of CD30+ T Lymphocytes with Progression
Authors: Vallacchi Viviana , Vergani Elisabetta , Camisaschi Chiara , Deho Paola , Cabras Antonello D. , Sensi Marialuisa , De Cecco Loris , Bassani Niccolò , Ambrogi Federico , Carbone Antonino , Crippa Federica , Vergani Barbara , Frati Paola , Arienti Flavio , Patuzzo Roberto , Villa Antonello , Biganzoli Elia , Canevari Silvana , Santinami Mario , Castelli Chiara , Rivoltini Licia , Rodolfo Monica
Published: April 2023

XLSX file - 15K, Supplementary Table S1.Clinicopathological data for the SNB samples analyzed in the training and validation studies.
Supplementary Figure 5 from Skin Tumorigenesis Stimulated by Raf Inhibitors Relies Upon Raf Functions That Are Dependent and Independent of ERK
Authors: Doma Eszter , Rupp Christian , Varga Andrea , Kern Florian , Riegler Bettina , Baccarini Manuela
Published: April 2023

PDF file - 213K, C‐Raf, but not B‐Raf ablation, prevents tumor development in GDC‐0879 treated K5‐ SOS‐F+ mice.
Supplementary Figure 2 from Transcriptional Profiling of Melanoma Sentinel Nodes Identify Patients with Poor Outcome and Reveal an Association of CD30+ T Lymphocytes with Progression
Authors: Vallacchi Viviana , Vergani Elisabetta , Camisaschi Chiara , Deho Paola , Cabras Antonello D. , Sensi Marialuisa , De Cecco Loris , Bassani Niccolò , Ambrogi Federico , Carbone Antonino , Crippa Federica , Vergani Barbara , Frati Paola , Arienti Flavio , Patuzzo Roberto , Villa Antonello , Biganzoli Elia , Canevari Silvana , Santinami Mario , Castelli Chiara , Rivoltini Licia , Rodolfo Monica
Published: April 2023

PDF file - 85K, Supplementary Figure S2.Representation of the results of the class comparison analysis of the gene expression data. In total, 3,078 genes were differentially expressed in the PP samples compared with all other SNBs. In the analysis, 333 genes were differentially expressed between the PN and the PP tumor-positive SNB samples, 58 genes were differentially expressed between all tumor-positive SNBs and the N samples, and 18 genes were differentially expressed between the PN and N samples.