bluuebunny/crossref_metadata_2025 huggingface dataset:
Periodontal Diseases and Lipid Profile in Systemic Sclerosis: an EUSTAR Cohort Experience
Authors: Ancuta Codrina , Pomirleanu Cristina , Iordache Cristina , Fatu Ana Maria , Popescu Eugenia , Ancuta eugen , Mihailov Claudia
Published: February 2020

Dental pathology is commonly described among patients with systemic sclerosis (SSc), a multisystem autoimmune disorder, and assumed to be multifactorial. We aimed to evaluate the periodontal status and to identify potential relation with SSc-specific parameters as well as serum lipid profile in a cross-sectional study on consecutive SSc. Standard assessments comprised dual, rheumatologic (disease subtype, clinical spectrum, inflammatory, immunological, lipid metabolism - total cholesterol and fractions, triglycerides), and dental evaluation (plaque index, bleeding on probing, pocket depth, clinical attachment level). 70.96% SSc developed oral manifestations, 51.61% periodontal disease, while one third severe aggressive periodontitis, particularly in diffuse SSc (p[0.05). Abnormal lipid pattern (low serum HDL- and high LDL-cholesterol, increased serum triglycerides, without significant modification in total cholesterol level) significantly correlated with diffuse SSc and skin involvement, disease duration, anti-topoisomerase 1 positivity, SSc activity and severity, as well as periodontitis (p[0.05). Our results clearly define an association between the presence and severity of periodontal disease and lipid anomalies in SSc, suggesting a potential link with early atherosclerosis via gingival inflammation and altered lipid metabolism.
A New Model for the Equation Describing the Cavitation Mean Depth Erosion Rate Curve
Authors: Micu Lavinia Madalina , Bordeasu Ilare , Popoviciu Mircea Octavian
Published: February 2020

Paper present a new relation describing the curve MDER(t) which mediates the experimentally obtained values of the mean depth erosion rates. These curves are used to characterize the cavitation erosion behavioor of materials tested in the Cavitation Laboratory of Timisoara Polytechnic University. Practically the new relation is an improvement of the analytical model established in 2004 by Bordeasu and coworkers, by introducing a supplementary element, which take into consideration the shape of the zone in where the cavitation erosion rate became stable and has linear variation. These addition allow increasing the approximation of the experimental values and also putting into evidence the tiny differences between different materials (various types of stainless steels, highly alloyed bronzes etc.) which till now were considered with similar resistance. Thus, the supplementary term allow a better differentiation resulting from the chemical composition, the structure and the mechanical properties.
The Effect of Mecury Contamination on Human Health and a Comparative Method of Extracting Hg(II) from Water Solution
Authors: Andoni Mihaiela , Savoiu Balint Germaine , Vlaia Vicentiu , Popovici Ramona Amina , Stanca Horia Tudor
Published: February 2020

In this paper it has been done an experimental work regarding the optimal conditions of removing mercury from water using ion exchange resins and cellulose xanthate (CX/Na). It were prepared water solution of HgCl2 with very well determined concentrations where it was added different amount of ion exchanger resin and CX/Na. The system was shaking 20, 40, 60 and 80 min. It has been found that the optimal conditions for removing of mercury from contaminated water solutions are 2.5 g/L CX/Na for 60 min shaking time for 100mg/L initial mercury concentration and 2.0 g/L CX/Na for 60 min shaking time for 50mg/L initial mercury concentration.
Thermal Cycling Influence on the Transformation Characteristics of a Ni50Ti48Nb2 Shape Memory Alloy
Authors: Gherghescu Ioana Arina , Ciuca Sorin , Jicmon Gabriela Liliana , Dumitrescu Ruxandra Elena , Branzei Mihai
Published: February 2020

The alloy was chosen in order to obtain a shape memory alloy having a wider hysteresis than equiatomic NiTi, that involves a better thermo-mechanical stability. Two samples investigated by differential scanning calorimetry (DSC) were previously annealed at 800oC/12 h and, respectively, 900 �C/12 h followed by furnace cooling. These were afterwards submitted to thermal cycling. The thermal cycling of a Ni50Ti48Nb2 alloy sample previously annealed at 900 �C/12 h results in lower critical points and higher hysteresis values as compared to those of the sample annealed at 800�C/12h, also submitted to thermal cycling. Thus, annealing a metallic part made of such an alloy at 900� C/12 h followed by thermal cycling prior to putting it into service enhances its reliability.
Chemical Physiology of Muscle Contraction
Authors: Pavel Liliana Lacramioara , Tiutiuca Carmen , Berbece Sorin Ioan , Condratovici Alina Plesea , Ioanid Nicoleta
Published: February 2020

The mechanical response of an isolated muscle to an excitant is not accompanied by any oxygen consumption increase; the additional amount of oxygen is not consumed as long as contraction and relaxation have not occurred. Thus, there are two contraction phases, an anaerobic (anoxidative) phase and an aerobic (oxidative) or recovery phase, during which the muscle resumes its previous stage. When the muscle is repeatedly excited in a nitrogen atmosphere, it strongly contracts at the beginning, but it gets quickly exhausted, since between contractions it cannot get the necessary oxygen for its recovery. Lactic acid gathers in the muscle, which becomes stiff. If it gets oxygen at the beginning of its fatigue, the lactic acid disappears and the muscle recovers its initial contraction strength. The lactic acid concentration at which complete skeletal muscle fatigue sets in (i.e. the lactic acid peak) ranges between 0.3 and 06%. In order to release the energy it needs for its contraction, the muscle does not depend on immediate oxidative processes. It continues to contract for a certain amount of time even when it is completely deprived of oxygen.
Interrelation Between Salivary pH, Buffer Capacity and Dental Caries in Underweight, Normal Weight and Overweight Children
Authors: Bud Anamaria , Bud Eugen , Esian Daniela , Pop Silvia , Bechir Anamaria , Pacurar Mariana , Curt-Mola Farah , Tarmure Viorica
Published: February 2020

The prevalence of dental caries in Romania remains high. The objective of this study is to analyse the link between dental caries, salivary pH and buffer capacity and the nutritional status in children. This cross-sectional study used a sample of 162 children, between the ages of 6 and 12 years, from Mures County, Romania. The prevalence of caries was measured using the decayed, missing, and filled teeth index for deciduous teeth (dmft index) and for permanent teeth (DMFT index). In addition, height and weight were assessed for each subject, and their body mass index (BMI) was calculated. The buffer capacity and the pH was determined after collecting stimulated saliva. Undernourished children presented a higher caries incidence and a lower salivary pH value compared with the normal weight and overweight children. Further longitudinal studies should be conducted in order to study the relationship between BMI, pH, dental caries and salivary buffer capacity. Future preventive programs should include nutrition control in order to prevent both the apparition of dental caries and of malnutrition.
Energy and Exergy Studies for Different Intensifying Processes of Malt Drying
Authors: Isopencu Gabriela , Mares Alina Monica , Jinescu Gheorghita
Published: February 2020

In this research, a comprehensive thermodynamic investigation through energy and exergy analyses is conducted to assess the performance of malt and mixtures of malt - inert add drying process. In this regard, energy and exergy efficiencies are evaluated with the experimental thermodynamic data for different techniques of malt drying (fixed, fluidized and modified fluidized bed with inert add). For all drying techniques analyzed, the study evidenced that energy utilization increases with drying agent velocity, drying time and temperature, meanwhile the energy utilization ratio decreases with this parameters. On the other hand, exergy loss and exergy efficiency increases with air velocity and drying temperature, but they have an antagonist behavior regarding with drying time: exergy loss decreasing in time, meanwhile the exergetic efficiency increases in time. The energetic values of the parameters for the fluidized bed are considerable smaller than those of fixed bed, which recommends the fluidization as intensification technique for malt drying. Also, the study evidenced the good influence on the energetic behavior of the fluidized bed, if the malt particle are mixed with a porous, hygroscopic inert add.
Characterization of Some Master Mg-X System (Ca, Mn, Zr, Y) Alloys Used in Medical Applications
Authors: Lupescu Stefan , Istrate Bogdan , Munteanu Corneliu , Minciuna Mirabela Georgiana , Focsaneanu Sergiu , Earar Kamel
Published: February 2020

Ultralight magnesium alloys are wide used in the medical field, especially for biodegradable implants. Although they are wide used, magnesium has low corrosion resistance. To improve this resistance, different types of alloys based on magnesium and Ca, Mn, Zr and Y can be developed. The main goal of the present paper is to investigate the properties of some master alloy based on Mg-X system (Ca ,Mn, Zr, Y) used in the development of biodegradable based alloys of Mg. The surface morphology was characterized using scanning electron microscopy (SEM), X-ray diffraction (XRD) and optical microscopy. After the XRD analysis, there was observed that some specific compounds were formed of Mg2Ca, Mg0.97Mn0.025, MgZr, Mg2Y, Mg24Y5 having the main Mg phase formed in the hexagonal structure. There were also evaluated the master alloys micro-hardness values in the range of 58.41 HV (Pure Mg), 67.97 HV (Mg-3Mn), 85.12 HV (Mg-25Zr), 131.8 HV (Mg-15Ca) and 291.45 HV (Mg-30Y). The corrosion resistance was developed using electrochemical testing in specific medium and there is shown that the corrosion rate increased significantly for the master alloys investigated, rather than pure magnesium. As a final conclusion structural properties of these alloys recommend them for usage as medical implants.
The Atmospheric Pollution Influence on the Surface Structures of Porous Geomaterials in Correlation with Some Natural Radionuclides
Authors: Pelin Vasile , Breaban Iuliana Gabriela , Sandu Ion , Gurlui Silviu
Published: February 2020

In the current context of climate and environmental changes, knowledge on the degradation and deterioration of the geomaterials mechanisms existing in the structure of both buildings and historical monuments becomes a priority due to the influence of atmospheric pollutants on apparent lithic surfaces. The aim of the paper is to highlight the impact of pollution on the surface structures of some porous carbonate rocks, where a series of radionuclides and heavy metals have been identified. Taking into account that these rocks are considered as commonly used local building material, being utilized also for the construction of the medieval and pre-modern historical monuments from the city of Iasi, the study draws attention to the detailed assessment of their conservation status from the built heritage in relation to the surrounding environment.
Green Energy for Sustainable Development in Romania�s Economy
Authors: Cristea Mirela , Dobrota Carmen Elena
Published: February 2020

Based on representative energy indicators, this study examines the need to adopt Green Energy Economy in Romania, in relation to the economic activity and demographic changes. The data used are the main energy indicators (the CO2 emissions, greenhouse gas emissions, the renewable energy consumption and the consumption of biofuel), the intensity of energy in economy, and the population number. The methodology consists in a quantitative analysis in EViews program. The results� interpretation will take into account that Romania has to continue to reduce the intensity of energy, by increasing the energy efficiency, focusing mainly on energy technologies with low-carbon.
Evaluation of Antioxidant Activity and Total Phenols Content in Selected Spices
Authors: Stanciu Gabriela , Cristache Nicoleta , Lupsor Simona , Dobrinas Simona
Published: February 2020

The total phenols contents and antioxidant activities of alcoholic extractive solutions of Ocimum basilicum (basil), Thymus vulgaris (thyme), Mentha piperita (mint), Rosmarinus officinalis (rosemary), Sativa officinalis (sage), Artemisia dracunculus (tarragon) and Coriandrum sativum (coriander) were examined using Folin-Ciocalteu method and ACL method, respectively. Extractive alcoholic solutions of above mentioned seven spices were analyzed during a period of five months in order to determine the optimal extraction time when the polyphenolic content was at maximum. The highest total phenolic contents were registered for rosemary (608.37 mg GAE/100 g d.w.), sage (530.66 mg GAE/100g d.w.) and mint (511.87 mg GAE/100g d.w.) In general the optimal extraction time of the total phenolic content was reached after 3 months of maceration, except thyme, tarragon (after two months) and coriander (after one month). The antioxidant capacity ranged between 1410.1 nmols Trolox/g d.w. for rosemary and 4.2560 nmols Trolox/g d.w. for tarragon.
The Effect of Enamel Matrix Derivate Proteins EMD on Ortodontically Induced Bone Resorption Based on Mini-implants
Authors: Vlasa Alexandru , Biris Carmen , Pacurar Mariana , Bud Anamaria , Bud Eugen , Bukhari Csilla , Imola Buka , Molnar Varlam Cristina , Maris Marius , Lazar Luminita
Published: February 2020

Amelogenine protein is the major component of the continuously secreted enamel extracellular matrix that controls the mineralization of enamel crystals. EmdogainTM is an extract of porcine fetal tooth material, a product based on the high degree of homology between porcine and human enamel proteins, composed primarily of amelogenine protein. It was created to promote the regeneration of periodontal tissues such as cementum, periodontal ligament and alveolar bone by stimulating normal development of these tissues, it is used to treat deep intraosseus defects.
The Role of Diet and Lifestyle Habits in Prevention of Cardiovascular Diseases in Moldavian and Transylvanian Population
Authors: Balint Iosif , Nagy Eniko Nemes , Csibi Monika , Tubak Nimrod , Olah Peter , Preg Zoltan , Sallo Marta German , Tilinca Mariana , Ormenisan Alina , Abram Zoltan , Fazakas Zita
Published: February 2020

The role of diet is crucial in the development and prevention of cardiovascular disease. The purpose of the current study was to describe dietary intake and assess health scores of children and adults by using a survey questionnaire on moldavian and transylvanian population, in order to evaluate whether it is necessary to introduce a prevention program for cardiovascular diseases in Romania. In 2015, a questionnaire was sent to 347 children and 583 adults in two counties in Romania where the climatic and topographic conditions are different. Participation rate in the children group was 56.48% moldavian / 43.51% transylvanian, respectively 39.62% moldavian / 60.37% transylvanian participants in the adult group. The questionnaire included a 44-item semi-quantitative food frequency questionnaire and questions on lifestyle for children and a 21- item semi-quantitative food frequency questionnaire and a health score for adults. Results were evaluated against the WHO recommendations of healthy diet. In Mures county the number of former smokers is significantly higher compared to Bacau county, and considerably more subjects report active smoking and exposure to passive smoking. The incidence of overweight and obesity was similar in the two counties, 68.14% in Bacau and 70.67% in Mures. More subjects from Bacau (94.35%) have regular exercise compared to those from Mures (85.38%), the difference is not quite significant. The majority of the subjects from Bacau county have a significantly healthier diet compared to those from Mures, consuming regularly eggs, meat and dairy products. Based on our data, only 16% of Romanian children reach the WHO recommendation for healthy nutrition regarding fruit and vegetable intake.Dietary habits of children and adults in Romania warrant improvements. Public health actions should be taken to increase the consumption of fruits and vegetables, decrease the consumption of saturated fats and sweets and also to increase the frequency of physical activity. These actions may be helpful in reducing the risks for overweight and cardiovascular diseases.
The Pattern of Ventricular Remodeling Influences the Level of Oxidative Stress in Heart Failure Patients
Authors: Goidescu Cerasela Mihaela , Farcas Anca Daniela , Anton Florin Petru , Vida Simiti Luminita Animarie
Published: February 2020

Oxidative stress (OS) is increased in chronic diseases, including cardiovascular (CV), but there are few data on its effects on the heart and vessels. The isoprostanes (IsoP) are bioactive compounds, with 8-iso-PGF25a being the most representative in vivo marker of OS. They correlate with the severity of heart failure (HF), but because data regarding OS levels in different types of HF are scarce, our study was aimed to evaluate it by assessing the urinary levels of 8-iso-PGF2aand its correlations with various biomarkers and parameters. Our prospective study included 53 consecutive patients with HF secondary to ischemic heart disease or dilative cardiomyopathy, divided according to the type of HF (acute, chronic decompensated or chronic compensated HF). The control group included 13 hypertensive patients, effectively treated. They underwent clinical, laboratory - serum NT-proBNP, creatinine, uric acid, lipids, C reactive protein (CRP) and urinary 8-iso-PGF2a and echocardiographic assessment. HF patients, regardless the type of HF, had higher 8-iso-PGF2a than controls (267.32pg/�mol vs. 19.82pg/�mol, p[0.001). The IsoP level was directly correlated with ejection fraction (EF) (r=-0.31, p=0.01) and NT-proBNP level (r=0.29, p=0.019). The relative wall thickness (RWT) was negatively correlated with IsoP (r=-0.55, p[0.001). Also 8-iso-PGF25a was higher by 213.59pg/�mol in the eccentric left ventricular (LV) hypertrophy subgroup comparing with the concentric subgroup (p=0.014), and the subgroups with severe mitral regurgitation (MR) and moderate/severe pulmonary hypertension (PAH) had the highest 8-iso-PGF2a levels. Male sex, severe MR, moderate/severe PAH, high LV mass and low RWT values were predictive for high OS level in HF patients.Eccentric cardiac remodeling, MR severity and PAH severity are independent predictors of OS in HF patients.
The Importance of Fluconazole in Treatment of Endogenous Endophtalmitis in Patients Prior Treated Using Negative Pressure Therapy for Wound Closure Contaminated with Meticillin-resistant Staphylococcus aureus
Authors: Alexa Anisia Iuliana , Ciuntu Roxana , Cantemir Alina , Anton Nicoleta , Danielescu Ciprian , Negru Robert , Bogdanici Camelia Margareta , Vasiluta Ciprian , Georgescu Stefan Octavian , Sirbu Paul Dan , Ciuntu Bogdan Mihnea
Published: February 2020

Severe infections with C. albicans should be treated promptly with antifungal agents, any delay in treatment increases the risk of endophthalmitis. The systemic Amphotericin B therapy is the gold standard in the treatment of endophthalmitis, but in the case of fungal infections it has not yet been determined. Numerous studies have shown that the use of Fluconazole is effective in the treatment of fungal endophthalmitis. In this paper, we report two cases (3 eyes) that have been presented for the same accusations of significant decrease of AV (visual acuity), ocular pain and blepharospasm suddenly installed, both of which required urgent antibiotic and intravenous antifungal treatment. Both are diagnosed with endogenous endophthalmitis and vitreous biopsy + VPP (pars plana vitrectomy) are performed, with a negative result of the vitreous culture. In both situations the treatment was with antibiotic and systemic antifungals. Postoperatively, evolution was favorable in the first case and less favorable in the second one. The prognosis depends on the virulence of the microorganisms and the time elapsed until initiation of the treatment. Also, the presence of risk factors such as diabetes, sepsis, recent abdominal surgery (C. Albicans is part of the comesary flora of the digestive tract) have influenced the prognosis decisively. Severe infections with C. albicans should be promptly treated with antifungal agents, any delay in treatment increases the risk of endophthalmitis. Even when prolonged treatment of candidemia is instituted, 3% of patients can develop endogenous endophthalmitis, so ocular evaluation is particularly important for patients immobilized in anesthesia and intensive care units.
The Study of Photoreversibility, Photopolimerization and Photocleavage Properties of Polyurethane Coumarin by Means of Electronic Spectrometry and AFM Methods
Authors: Gurlui Silviu , Buruiana Emil , Sandu Ioan Gabriel , Strat Mitachi
Published: February 2020

The spectroscopic and photochemical properties of polyurethane coumarin (PUC) in dimethyl sulf-oxide (DMSO), thetra hydro furan (THF), dimethyl formamide (DMF) and film state were investigated at room temperature under one photon excitation. The results show that under irradiation of l ] 310 nm photodimerization process are increased and under UV irradiation with l[ 260 nm, photocleavage of polymer have been evidenced, too.
Preliminary Data Regarding the Effects of Oxytocin Administration on the Oxidative Stress Status of Zebrafish (Danio Rerio)
Authors: Balmus Ioana Miruna , Strungaru Stefan , Nicoara Mircea , Plavan Gabriel , Cojocaru Sabina Ioana , Simion Laurentiu
Published: February 2020

Zebrafish are important animal models widely used in molecular biology research. To our best knowledge, no previous study on OT effects in zebrafishes� oxidative stress status was performed. Moreover, while the zebrafish are naturally producing isotocin, the investigation of its homologue OT effects may provide consistent evidence of the possible influence of oxytocin in isotocin naturally producing teleosteens. In this way, we aimed to analyse the influence of water exposure (e.g. branchial and tegmental exposure) on two different doses of OT (33.2 ng/mL and 66.4 ng/mL) on the adult zebrafish (n = 15) oxidative stress markers. Significant differences and correlations were found in the zebrafish exposed to a higher OT concentration, although lipid peroxidation tended to decrease as the OT concentration increased. Thus, it seems that oxytocin is cross-reacting and exerts clear effect on oxidative stress status main parameters in zebrafish.
Correlation Between the Tyrozinkinazine Inhibitor Sunitinib - Dose, Schedule of Administration and Adverse Events
Authors: Stanculeanu Dana Lucia , Mihaila Raluca Ioana , Zob Daniela , Toma Oana Catalina , Mihaila Raluca Ioana , Toader Elena , Boanca Mihaela , Poroch Vladimir , Simion Laurentiu
Published: February 2020

Sunitinib, a multi-targeted receptor tyrosine kinase inhibitor, has demonstrated survival benefit in patients with metastatic renal cell carcinoma (mRCC) and is generally well tolerated with most adverse events, manifesting as mild to moderate in severity. The most frequent related adverse events include hand-foot syndrome (HFS), hypertension, proteinuria, cardiac toxicities, myelosuppression, fatigue/asthenia, hypothyroidism, diarrhea and hepatotoxicity. The study aims to determine incidence of adverse events among patients with metastatic renal cell carcinoma (mRCC) treated Sunitinib within five years from 2010 to 2015 and comparing the results with data from literature. The study included a total of 56 patients treated with Sunitinib, with a dose of 50 mg (Schedule 4/2). Due to adverse events and individual safety and tolerability, at the indication of the personal clinician, 11 patients needed dose reduction, with a continuous dose of 37.5 mg, daily and 28 patients continued the dose of 50 mg taken daily, on a different schedule (2/1 schedule). The most important toxicities were anemia, leukopenia, thrombocytopenia, gastrointestinal effects (diarrhea), fatigue and hypertension. After dose reduction or modified schedule the incidence of the most frequent toxicities (HFS, leukopenia, thrombocytopenia and fatigue) decreased, but hypertension was still observed in 30% of patients. The results are similar with data from literature. Early identification of individuals at risk and monitoring patients during Sunitinib treatment is very important and it can facilitate early intervention with prophylactic measures or supportive treatment, thus increasing quality of life and adherence to treatment. Further studies need to establish which targeted population can benefit the most from adjusted regimens and to correlate them with prognostic factors for survival.
Interrelations Between Anesthetic Substances, General Condition of the Patient and Implant Rehabilitation Procedure
Authors: Rosu Manuel Florin , Agop Forna Doriana , Forna Norina Consuela
Published: February 2020

The purpose of this study is to quantify the existing interrelationship between the anesthetic substances used in the implanto-prosthetic rehabilitation procedures with the general state of the patient, as well as the specific implant rehabilitation work.The analyzed lot brought together 110 patients, candidates for implanto-prosthetic rehabilitation, subjected to a general and local evaluation protocol for choosing general anesthesia in accordance with the general state and complexity of the implanto-prosthetic algorithm. Regarding connection between therapeutic approaches in oral implantation and types of anesthesia , we obtained correlative aspects between the use of inhalosedation and implantation algorithm in 80% clinical cases and augmentation with implantation was found in 20%.General anesthesia with Midazolam has been correlated with implantation and augmentation in 77% clinical cases and sinus lift and implantation was found in 23% clinical cases.General anesthesia with Midazolam was used in 64% clinical cases with implantation and sinus lift and 36% clinical cases with implantation.Careful monitoring of the patient and proper dental surgery where the intervention is performed are the key for a therapeutic success regarding sedation and anesthesia.
Simulation of Aerobic Granular Sludge Process Efficiency
Authors: Manea Elena Elisabeta , Bumbac Costel , Tiron Olga , Dinu Razvan Laurentiu , Badescu Valeriu Robert
Published: February 2020

Using aerobic granular sludge for wastewater treatment has multiple advantages compared to conventional activated sludge systems, most important being the ability of simultaneous removal of the pollutants responsible for eutrophication: organic load, compounds of nitrogen (NH4+; NO3-) and phosphorus (PO43-). The advantages are currently exploited for developing the next generation of wastewater treatment systems while the identified limitations are approached by experimental and theoretical researches worldwide. The aim of the study consists in evaluating the possibility of predicting the system�s response to different changes in the influent wastewater loadings. The paper presents simulations results backed up by experimental data for pollutants removal efficiencies evaluation for a sequential batch reactor (SBR) with aerobic granular sludge. The mathematical model is based on the activated sludge model no. 3, which was updated by considering the simultaneous biological nitrification (NH4+NO3) and denitrification (NO3-N2) processes, thus complying with the biochemical reactions occurring in aerobic granular sludge sequential batch reactors. The model developed was validated by the experimental results obtained on a laboratory scale SBR monitored for over a month.
Water Quality Index, a Useful Tool for Evaluation of Danube River Raw Water
Authors: Paun Iuliana , Chiriac Florentina Laura , Marin Nicoleta Mirela , Cruceru Liliana Valeria , Pascu Luoana Florentina , Lehr Carol Blaziu , Ene Corina
Published: February 2020

The Danube River is the major source of drinking water supply for the cities in the southern part of Romania. The study was a descriptive-analytical one and lasted for 9 month. Samples were taken monthly between March 2016 and November 2016. Six sampling sites were selected to evaluate the spatial and temporal changes of water quality along the river. The samples were analyzed based on the standard methods for the following parameters: pH, conductivity (EC), NH4+, NO3-, Cl -, suspended solids, PO43-, SO42-, metals (Fe, Cd, Cr, Pb, Ni, Hg, As, Zn, Cu, Mn). The obtained values were compared with those imposed by the Romanian environmental legislation. An efficient and simplified method to express the quality of water used for consumption is provided by the Water Quality Index (WQI). WQI reflects the quality of water in a single value by comparing data obtained from the investigation of a number of physico-chemical parameters to the existing limits. The evaluation of water quality was performed using the Water Quality Index of the Canadian Council of Ministries of the Environment (CCME WQI). Water quality indices were classified as: excellent, good, medium, bad and very bad. The results indicated the water quality classification as �good� in all six sampling selected sites.
Study of Air Pollution and Atmospheric Stability in Ciuc Basin - Romania
Authors: Szep Robert , Keresztes Reka , Korodi Attila , Tonk Szende , Craciun Mihaela Emanuela
Published: February 2020

The atmospheric stability plays an important role in the accumulation of air pollutants and greatly influences their degradation, dispersion and deposition. These atmospheric qualities can be determined with various methods (Richardson number, Monin - Obukhov length, SRDT method) and the pollutant concentration increase demonstrates the atmospheric stability. In this study the cold periods were the most stable as well the PM10 and CO pollutants had high concentrations. Between these two pollutants the correlation is high because their sources are the same: transport and biomass burning. The study of hourly averages highlighted the importance of traffic intensity since the concentration variation follows the traffic intensity. An increase in the wind speed in the basin results in the pollutants concentrations decrease, the negative correlation with the temperature indicating the importance of the photochemical processes.
In vivo Experiments (Carassius gibelio Bloch) on Copper Homeostasis Alteration After Lead Intoxication and Natural Biologic-active Principles Treatments
Authors: Nicula Marioara , Pacala Nicolae , Stef Lavinia , Pet Ioan , Iancu Tiberiu , Dronca Dorel , Ahmadi Mirela , Gherbon Adriana , Deleanu Bogdan
Published: February 2020

Minerals are involved in the most metabolic pathways and are necessary for living organisms in different concentrations. When the concentration of these biominerals is unbalanced due to different factors, the metabolic processes are disturbed and the organism tries to find recovery solutions. Cu is one mineral indispensable for living organism, also for fishes, and its concentration it could be drastically reduced by the presence of high concentration of some heavy metals � like Pb, due to antagonistic effect. Our research evaluates the Pb toxic potential on Carassius gibelio Bloch on Cu distribution in different tissues and two natural solutions for potentiation of antagonistic effect of Pb on Cu. We worked on four different fish groups: control group (C); and for three experimental groups we add 75 ppm Pb � as Pb(NO3)2 x �H2O into the water from aquarium. To potent the Pb toxicity we add into the grounded fish feed 2% lyophilized garlic to E3 group and 2% chlorella to E4 group. Every group had 30 fishes in separate aquarium, the fishes were fed every 2 times a day and had 12h alternate light and dark. After 21 days of experiment the fishes were euthanized with cloves oil and the tissue samples were collected (brain, gill, gonads, intestine, kidney, liver, striated muscle � epaxial myotomes, cardiac muscle, and skin). The samples were analytical prepared for AAS in order to determinate the Cu concentration in all tissue samples. The results presented the best protection of garlic against antagonistic effect of Pb on Cu in brain and testicles, and the lowest protection in muscle-striatal; while chlorella best protection was observed in heart muscle, brain, kidney and liver, and lowest protection in muscle-striatal.
Studies on Adhesion of Composite Resins and Glass-Ionomer Cements in Open-Sandwich Technique
Authors: Ghiorghe Cristina Angela , Iovan Gianina , Andrian Sorin , Nica Irina , Topoliceanu Claudiu , Pancu Galina
Published: February 2020

The aim of this study was to assess the quality of the interface between dental root cement and some restorative materials used in the open sandwich technique. Standardised cavities were prepared on the buccal and oral surfaces of 30 human molars with the gingival margin situated in root cement. The teeth were randomly divided in 3 groups. Different materials combinations were used in buccal and oral cavities. In the control group, the cavities were filled only with composite resins (Filtek Z250-3M ESPE and Zmack Comp-Zermack). In the test groups the cavities were restored using an open sandwich technique as follows: in group 1 Filtek Z250 in combination with Dyract, respectively Ketac Molar Easymix; in group 2 Zmack Comp in combination with Dyract, respectively Ketac Molar. The teeth were stored in 1% methylene blue solution, for 24 hours. The samples were longitudinally sectioned through the centre of restorations and the degree of dye penetration as well as the morphology of the interface between the root cement and the restorative material were evaluated by optical microscopy and SEM. The results showed less microleakage and and adhesive failures in open sandwich restorations with Zmack Comp and Dyract combination.
Thermal Behaviour of Candesartan Active substance and in pharmaceutical compounds
Authors: Tita Ioana Cristina , Marian Eleonora , Tita Bogdan , Toma Claudia Crina , Vicas Laura
Published: February 2020

Thermal analysis is one of the most frequently used instrumental techniques in the pharmaceutical research, for the thermal characterization of different materials from solids to semi-solids, which are of pharmaceutical relevance. In this paper, simultaneous thermogravimetry/derivative thermogravimetry (TG/DTG) and differential scanning calorimetry (DSC) were used for characterization of the thermal behaviour of candesartan cilexetil � active substance (C-AS) under dynamic nitrogen atmosphere and nonisothermal conditions, in comparison with pharmaceutical product containing the corresponding active substance. It was observed that the commercial samples showed a different thermal profile than the standard sample, caused by the presence of excipients in the pharmaceutical product and to possible interaction of these with the active substance. The Fourier transformed infrared spectroscopy (FT-IR) and X-ray powder diffraction (XRPD) were used as complementary techniques adequately implement and assist in interpretation of the thermal results. The main conclusion of this comparative study was that the TG/DTG and DSC curves, together with the FT-IR spectra, respectively X-ray difractograms constitute believe data for the discrimination between the pure substance and pharmaceutical forms.
Applicability of Zirconia-Prefabricated Crowns in Children with Primary Dentition
Authors: Bica Cristina , Pescaru Paul , Stefanescu Ada , Docan Mihaela Oana , Martha Krisztina , Esian Daniela , Cerghizan Diana
Published: February 2020

Zirconia dioxide represents the current alternative in restoring primary teeth, being the most promising restorative material through its properties that offer. Zirconia crowns main properties are its aesthetics, resistance to fracture and compression, biocompatibility, alternative for the patients that are allergic to Ni-Cr. This cross-sectional study pointed out the correlations between the rate of applicability of the Ni-Cr crowns and the ZrO2 crowns, as well as the range of applicability of the ZrO2 crowns on temporary teeth among practitioners. The method of choice in the case of extensive carious lesions treatment on the primary teeth was the restoration using filling materials. From the 33,2% of the dentists who decide to apply a pedodontics crown, 75% use the Ni-Cr crowns, and only 25% of them choose the ZrO2 crown (p[0.0001). The applicability of ZrO2 crowns in pediatric dentistry is quite reduced, despite their physiognomic advantages, their excessive cost can also be an impediment for the patient�s parents.
Rheological Behaviour of Cold Creams with Cinnamon and Thuja Alcoholic Extract
Authors: Cobzaru Claudia , Gherghescu Oana , Aursulesei Andreea Eliza , Ibanescu Constanta , Danu Maricel , Apostolescu Gabriela Antoaneta , Cernatescu Corina
Published: February 2020

In this paper the rheological behavior of three cold creams obtained in laboratory have been made, such as: simple cold cream, one cream with cinnamon extract and one cream with thuja extract. All three creams have a pseudo-plastic time-dependent rheological behavior, also exhibiting a velvety feeling and being easily applied on skin. By adding the alcoholic extracts of cinnamon and thuja, the creams became more fluid and soft and could be applied better.
The Importance of Specific Antibiotic Therapy in the Evolution of Retinal Vasculitis
Authors: Anton Nicoleta , Alexa Anisia Iuliana , Cantemir Alina , Ciuntu Bogdan Mihnea , Timofte Daniel , Bogdanici Camelia Margareta , Ciuntu Roxana Elena
Published: February 2020

Ischemic retinal vasculitis is an inflammation of retinal blood vessels associated with vascular occlusion and retinal hypoperfusion. It may cause visual loss secondary to macular ischaemia, macular edema and neovascularization leading to vitreous hemorrhage, fibroblastic proliferation and retinal detachment by traction. Corticosteroids with or without immunosuppressive medication are the main treatment in retinal vasculitis associated with laser photocoagulation of retinal ischemic regions. In Lyme�s disease, etiologic treatment is achieved with Ceftriaxone that can be associated in some cases with corticosteroids. In this paper, we report about a patient who presented for the decrease of about 1.5 months of painless, asymptomatic visual acuity (VA). The patient was diagnosed with oclusive retinal vasculitis and followed a series of investigations to identify the etiology. The presence of anti-borelial antibodies required the administration of specific treatment with ceftriaxone 1g / 12h to which was added after 48h systemic corticosteroids, with slow evolution favourable. This association of retinal vasculitis - Lyme was quite rare and difficult to demonstrate. The prognosis of patients with retinal vasculitis is variable. Many patients may have a relatively benign condition or may have a dramatic response to systemic imunosuppressive therapy and will retain visual function. In the long run, despite specific treatment, it is unfavorable due to the evolution of retinal atrophy with visual field and visual function. Patients with ischemic retinal vasculitis represent a significant management challenge and, if not treated properly, can lead to a severe, irreversible visual loss.
Influence of Applied Phytosanitary Treatments and Climatic Crop Year on Zinc Content in Wines from Tohani Vineyard
Authors: Calin Catalina , Scaeteanu Gina Vasile , Madjar Roxana Maria , Cangea Otilia
Published: February 2020

Metallic ions present a great importance in oenological practice and usually are present in wines in levels that are not hazardous. Among all metallic ions, zinc presents a great interest because may cause the persistence of the wine sour taste and by the side of Al, Cu, Fe and Ni, contribute to the haze formation and the change of color. The present study was focused on measuring the concentration levels of mobile zinc from vineyard soil before and after phytosanitary treatments and zinc content from white (Feteasca Alba - FA, Riesling Italian - RI, Sauvignon Blanc - SB, Tamaioasa Rom�neasca - TR), rose (Busuioaca de Bohotin - BB) and red (Feteasca Neagra - FN) wines within the wine-growing Tohani area, Romania. Other objective was to investigate of the influence of crop year and variety on zinc levels found in wine samples. Mobile zinc content for all analyzed soil samples is low ([1.5 mg/kg). Analyses indicated that zinc content found in wines was below 5 mg/L, limit set by Organisation Internationale of Vine and Wine (OIV). Also, it was found that red wines contain zinc in higher concentrations than white ones.
Could the Old Poly(methylmethacrylate) Face Arrising Challanges of New Advanced Technologies for Dental Prosthesis Manufacturing?
Authors: Totu Eugenia Eftimie , Cristache Corina Marilena
Published: February 2020

The biocompatibility, relatively low cost and excellent aesthetic appearance of polymer Poly(methyl methacrylate) (PMMA) makes it the material of choice for fabricating partially and complete dentures. Nowadays the emerging 3D printing technique imposed itself as reliable solution for obtaining dental devices. However, extensive usage of such technique is still limited due to the materials available. Despite PMMA�s drawbacks, mainly related to bacterial contamination, wear and mechanical failures, composite polymeric matrix has issued high interest lately. An important improvement in basic material properties have been achieved due to the inclusion of nanosystems, either nanoparticles or nanotubes. The newly shown versatility of reinforced PMMA sustains it as the best alternative for stereolithography (3D printing) technique. This paper highlights the improvements of PMMA by adding different type of nanofillers. Therefore, prospective randomized clinical in vivo studies with the use of biocompatible tested modified filled PMMA and modern technologies should be performed.
Modular Simulation to Determine the Optimal Operating Policy of a Batch Reactor for the Enzymatic Fructose Reduction to Mannitol with the in situ Continuous Enzymatic Regeneration of the NAD Cofactor
Authors: Crisan Mara , Maria Gheorghe
Published: February 2020

Novel coupled enzymatic systems reported important applications in the industrial bio-catalysis. Multi-enzymatic reactions can successfully replace complex chemical syntheses, using milder reaction conditions, and generating less waste. For such systems acting simultaneously, the model-based engineering calculations (design, reactor operation optimization) are difficult tasks, because they must account for interacting reactions, differences in enzymes optimal activity domains and deactivation kinetics. The determination of the optimal operating mode (enzyme ratios, enzyme feeding policy, temperature, pH) often turns into a difficult multi-objective optimization problem with multiple constraints to be solved for every particular system. The paper focuses on applying a modular screening procedure that can identify the optimal operating policy of an enzymatic reactor, which minimizes the enzyme consumption, given the process kinetic model, and an imposed production capacity. Following an optimization procedure, the process effectiveness is evaluated in a systematic approach, by including simple batch reactor (BR), batch with intermittent addition of the key-enzyme following certain optimal policies (BRP). Exemplification is made for the case of the enzymatic reduction of D-fructose to mannitol by using suspended MDH (mannitol dehydrogenase) and NADH (Nicotinamide adenine dinucleotide) cofactor, with the in-situ continuous regeneration of the cofactor by the expense of formate degradation in the presence of suspended FDH (Formate dehydrogenase).
Dual DTM-Padé approximations on free convection MHD mass transfer flow of nanofluid through a stretching sheet in presence of Soret and Dufour Phenomena
Authors: Saha Dibyendu , Sengupta Sanjib
Published: February 2020

A theoretical study is made to investigate heat and mass transfer analysis on the single phase flow of an electrically conducting, Al2O3-Water nanofluid over a linearly stretching sheet in presence of Soret and Dufour effects. An applied magnetic field is considered normal to the flow, while the effect of induced magnetic field got neglected for small magnetic Reynolds number’s value of the flow field relative to the applied field. Since voltage difference at the lateral ends of the sheet is very small, the influence of the electric field is thus omitted. The governing equations representing the physical model of the fluid flow is solved by means of DTM-Padé approximations. The acquired results show that an increase in the Soret number (Dufour number) decreases (increases) the temperature profiles but increases (decreases) the concentration profiles. The axial velocity profiles found decreasing with increasing values of the magnetic parameter. Both chemical reaction and thermal radiation parameters maximize the temperature profiles whereas a reverse phenomenon is seen on concentration profiles. The obtained tables show that increasing nanoparticle volume fraction escalates skin-friction coefficient, Nusselt number and Sherwood number whereas an increase in Richardson number decreases the Nusselt number but increases the Sherwood number.
Behavioral Intention Towards “Halal Hotels”: Religiosity or Ethnicity?
Authors: Md. Ithnan Izwan Harith , M. Ariffin Ahmad Azmi
Published: February 2020

The primary purpose of this study is to empirically examine and compare the effects of religiosity and ethnicity in influencing behavioral intention towards halal hotels concept. Is it the religion or ethnic values that really matters in selecting an Islamic concept of hotel such as the halal hotel? This study involving 492 respondents randomly selected among travelers at the Kuala Lumpur International Airport used SEM as the main method to test the hypotheses. Underpinned by the Theory of Reasoned Action (TRA), the findings of this study revealed that religiosity (represented by the construct of religious commitment) significantly influence behavioral intention towards halal hotels via attitude while ethnicity (represented by ethnic identity) has no significant influence on intention to patronage a halal hotel. Theoretically, this present study help extends the TRA model by incorporating religiosity factor in the context of Islamic tourism. With regard to practical implications, the findings provide inputs to the hoteliers particularly in the hotel’s positioning theme development as well as marketing communication strategies.
Point-to-Point: A Reply to “A Critique to ‘Using Rasch Analysis to Create and Evaluate a Measurement Instrument for Foreign Language Classroom Speaking Anxiety’ ”
Authors: Apple Matthew
Published: February 2020

In his response to my paper concerning the use of the Rasch model for creating and evaluating foreign language classroom speaking anxiety (Apple, 2013), Dr. Panayides makes some interesting observations; however, there also appear to be several points of misinterpretation of the study results. The initial issue is his opening assertion that my paper was designed to show advantages of the Rasch model over classical test theory (CTT) models as well as item response theory (IRT) models. In fact, the paper was designed only to demonstrate the advantages of the Rasch model for Japan-based classroom teachers of English. I made no mention whatsoever of other IRT models. I also did not set the Rasch model against all CTT methods; I merely demonstrated that simple descriptive statistics were not as informative or useful as Rasch analysis when creating and evaluating questionnaires.