bluuebunny/crossref_metadata_2025 huggingface dataset:
Стратегічні напрями розвитку ринку логістичних послуг в Україні
Authors: Шкуренко Ольга , Григоренко Анастасія
Published: December 2021

Анотація. Геостратегічне положення України та активний розвиток електронної комерції як активного споживача логістичних послуг на тлі глобалізації світового ринку і зростання обсягів транзитних перевезень свідчить про великий потенціал держави у даній сфері, про доцільність розвитку логістичного ринку як однієї із пріоритетних галузей народного господарства.

Доведено, що саме на логістиці будується взаємодія між суб’єктами підприємництва та підвищення їхньої економічної ефективності. З точки зору світового досвіду та сучасних тенденцій розвитку глобального ринку логістичних послуг Україна знаходиться на етапі формування та консолідації галузі, значно поступаючись західним країнам, як з якості, так і за комплексністю послуг, які надаються національними транспортно-логістичними компаніями.

Виокремлено основних операторів логістичних послуг в Україні. Проведено аналіз стану ринку логістичних послуг у секторах вантажних перевезень різними видами транспорту та складської логістики за період 2016-2020 рр., за результатами якого, сформовано поточні тенденції на логістичному ринку.

Узагальнено напрями розвитку ринку логістичних послуг в Україні та виокремлено інструментарій підвищення ефективності логістики.

Визначено пріоритетні напрями розвитку ринку логістичних послуг в Україні, а саме впровадження конкурентної та ефективної транспортної системи; інноваційний розвиток транспортного сектору через реалізацію стратегічних інноваційних проєктів; забезпечення екологічно чистого та енергоефективного транспорту; впровадження цифрових рішень на транспорті. Саме розвиток ринку логістичних послуг за цими напрямами дозволить підвищити ефективність ринку логістики, що призведе до появи на ринку більшої кількості компетентних провайдерів комплексних логістичних послуг, приваблення на ринок закордонних гравців, що матиме позитивний вплив на господарство країни в цілому.

Ключові слова: логістика; ринок логістичних послуг; вантажні перевезення; розвиток;інструментарій логістики; стратегія.
Інноваційні інформаційні технології в підготовці та управлінні персоналом
Authors: Федорова Юлія , Єльникова Галина
Published: December 2021

Анотація. В умовах цифрової революції в економіці та менеджменті відбуваються активні зміни.Саме в умовах невизначеності, запровадження інноваційних заходів та постійний змін на зміну класичному навчанню та управлінню персоналом мають приходити новітні інформаційні технології.

Все частіше інноваційні технології навчання дозволяють персоналу отримувати знання онлайн, що дозволяє реалізовувати навчальні програми у рамках концепції безперервного навчання. Безліч сучасних організацій спрямовані на зміцнення своєї конкурентоспроможності за рахунок збільшення вартості людського капіталу шляхом навчання та розвитку власного персоналу. Кожна організація підходить до питання навчання співробітників виходячи з власного бачення: деякі підвищують кваліфікацію за рахунок тренінгових центрів, зовнішніх навчальних програм, інші наймають тьютора або формують власні  учбові центри та команди. В будь-якому разі виникає потреба в застосуванні ефективних технологій навчання персоналу.У статті подано сучасні IT-технології супроводу управління персоналом у цифровій економіці.

У рамках дослідження сучасних  інформаційних технологій розглянуть наступні: AI(Artificial Intelligence), хмарна технологія Cloud ERP (Enterprise Resource Planning – Програмне забезпечення для планування ресурсів), віртуальна реальність (VR) та доповнена реальність (AR), blockchain (блокчейн), bigdata, digital-learning. Розглянуто: HRIS (інформаційна система людських ресурсів), HCM (управління людським капіталом), HRMS (система управління людськими ресурсами), TMS (система управління талантами), ATS (система відстеження претендентів), LMS (система управління навчанням).

У статті розглянуть найбільш ефективні сучасні технології навчання персоналу, такі як геймифікація, коучинг, buddying, shadowing, тощо. Зазначено, що застосування інноваційних технологій навчання персоналу, таких як блокчейн, хмарні технології, віртуальна реальність, bigdata, «digital-learning» здатне зміцнити підприємство, підвищити його конкурентоспроможність, сприятиме підвищенню економічних результатів його діяльності. Технологія «digital-learning» дозволяє на практиці підвищити рівень якості навчання співробітників, знизити часові витрати на навчання, отримати прискорений практичний результат на робочому місці. Розглянуті технології мають перспективи розвитку та застосування у сучасному менеджменті.

Ключові слова: цифрова економіка, IT-технології, навчання персоналу, blockchain (блокчейн), HRIS (інформаційна система з людських ресурсів), HCM (управління людським капіталом), TMS (система управління талантами), ATS (система відстеження претендентів), digital-learning.
Limit theorems for numbers satisfying a class of triangular arrays
Authors:   Institute of Data Science and Digital Technologies, Vilnius University, 04812 Vilnius, Lithuania, Belovas Igoris
Published: December 2021

The paper extends the investigations of limit theorems for numbers satisfying a class of triangular arrays, defined by a bivariate linear recurrence with bivariate linear coefficients. We obtain the partial differential equation and special analytical expressions for the numbers using a semi-exponential generating function. We apply the results to prove the asymptotic normality of special classes of the numbers and specify the convergence rate to the limiting distribution. We demonstrate that the limiting distribution is not always Gaussian.
On homotopy nilpotency
Authors:   Faculty of Mathematics and Computer Science, University of Warmia and Mazury, Słoneczna 54 Street, 10-710 Olsztyn, Poland, Golasiński Marek
Published: December 2021

We review established and recent results on the homotopy nilpotence of spaces. In particular, the homotopy nilpotency of the loop spaces \(\Omega(G/K)\) of homogenous spaces \(G/K\) for a compact Lie group \(G\) and its closed homotopy nilpotent subgroup \(K \lt G\) is discussed.
Análise do ambiente educacional de uma escola médica brasileira à luz das demandas do ensino remoto
Authors: Serra Sandra Torres , Taquette Stella Regina , Rodrigues Nadia Cristina Pinheiro , Corrêa Letícia Moraes , Bteshe Mariana
Published: December 2021

A necessidade de distanciamento social  provocou impactos na formação médica, que já sofria processo de mudanças. Com a adoção do ensino remoto, ocasionada pela pandemia da Covid-19, as escolas médicas revisaram práticas educativas e a relação professor-aluno em novos cenários. Nosso objetivo é analisar o ambiente educacional de um curso de graduação de medicina contextualizando-o à nova realidade, identificando aspectos do curso que devem ser revistos para favorecer as transformações necessárias. Aplicamos questionários sociodemográficos e Dundee Ready Education Environment Measure (DREEM) a alunos do primeiro, terceiro e sexto anos do curso de medicina de uma universidade pública brasileira entre agosto e novembro de 2019. Os alunos avaliaram negativamente o ambiente educacional, sendo aspectos concernentes à motivação, uso inadequado do tempo, incentivo à educação permanente percebidos como pouco estimulados e que precisam ser melhorados, objetivos pedagógicos pouco esclarecidos e professores autoritários. Na análise dos dados destacamos as percepções dos alunos sobre motivação e estímulo para aprender; relação professor-aluno; autonomia e estímulo à educação continuada; avaliação, e prática de feedback. Os resultados indicam que a adoção de metodologias de ensino centradas no professor não favorece a participação ativa do aluno e não o encoraja à construção do conhecimento. A modalidade remota de ensino exige ressignificar práticas educativas e lugares ocupados por professores e alunos no processo de ensino-aprendizagem. Atividades de aprimoramento docente, revisão dos métodos de ensino e de avaliação, e maior participação de alunos e professores nos processos de mudança são necessárias.
Percepção de alunos do Ensino Médio sobre o uso de Plantas Medicinais: uma ferramenta didática nas disciplinas de Biologia e Química em Quirinópolis, Goiás, Brasil
Authors: Morais Isa Lucia de , Nascimento Luciano Aparecido do , Santos Aline Bezerra da Silva , Guimarães Brenda de Oliveira
Published: December 2021

As disciplinas de Biologia e Química podem ser utilizadas como ferramentas para disseminação e ampliação do conhecimento etnobotânico quanto ao uso de plantas medicinais. O despertar deste conhecimento nos alunos contribui para a melhora do interesse pelas ciências experimentais e, consequentemente, propicia um sentimento de pertencimento à natureza por parte dos envolvidos. Neste contexto, esta pesquisa objetivou avaliar a percepção de alunos do Ensino Médio sobre o uso de plantas medicinais em Quirinópolis, Goiás. A pesquisa foi conduzida com a aplicação do questionário 1, seguida por uma aula prática utilizando o método de tintura na preparação do medicamento com plantas medicinais, e, finalizando com a aplicação do questionário 2. Para realização da aula prática, os alunos coletaram as plantas e as trouxeram para o Laboratório de Química/Biologia. A maioria dos estudantes afirmou fazer uso de plantas para fins medicinais com orientação de familiares. Foram citadas 12 espécies vegetais, a maioria exótica, adquiridas, pela maioria, de cultivo próprio, e as mais citadas Plectranthus barbatus Andrews, Chenopodium ambrosioides L., Matricaria chamomilla L. e Bidens pilosa L. A parte mais usada foram as folhas, a forma de preparo predominante foi infusão e o principal uso foi para o tratamento da gripe. A aula prática foi considerada pelos alunos como uma vivência inovadora e de profícuo saber científico. A maioria deles acredita que o conhecimento sobre plantas medicinais pode contribuir para o aprendizado de Química e Biologia e a experiência desperta o interesse nas aplicações práticas dos conceitos científicos abordados em sala de aula.
Proliferation of Mouse Prostate Cancer Cells Inflamed by Trichomonas vaginalis
Authors: Kim Sang-Su , Kim Kyu-Shik , Han Ik-Hwan , Kim Yeseul , Bang Seong Sik , Kim Jung-Hyun , Kim Yong-Suk , Choi Soo-Yeon , Ryu Jae-Sook
Published: December 2021

Our objective was to investigate whether inflammatory microenvironment induced by Trichomonas vaginalis infection can stimulate proliferation of prostate cancer (PCa) cells in vitro and in vivo mouse experiments. The production of CXCL1 and CCL2 increased when cells of the mouse PCa cells (TRAMP-C2 cell line) were infected with live T. vaginalis. T. vaginalis-conditioned medium (TCM) prepared from co-culture of PCa cells and T. vaginalis increased PCa cells migration, proliferation and invasion. The cytokine receptors (CXCR2, CCR2, gp130) were expressed higher on the PCa cells treated with TCM. Pretreatment of PCa cells with antibodies to these cytokine receptors significantly reduced the proliferation, mobility and invasiveness of PCa cells, indicating that TCM has its effect through cytokine-cytokine receptor signaling. In C57BL/6 mice, the prostates injected with T. vaginalis mixed PCa cells were larger than those injected with PCa cells alone after 4 weeks. Expression of epithelial-mesenchymal transition markers and cyclin D1 in the prostate tissue injected with T. vaginalis mixed PCa cells increased than those of PCa cells alone. Collectively, it was suggested that inflammatory reactions by T. vaginalis-stimulated PCa cells increase the proliferation and invasion of PCa cells through cytokine-cytokine receptor signaling pathways.
Recent Spatial and Temporal Trends of Malaria in Korea
Authors: Kim Yeong Hoon , Ahn Hye-Jin , Kim Dongjae , Hong Sung-Jong , Kim Tong-Soo , Nam Ho-Woo
Published: December 2021

This study was done to provide an analytical overview on the latest malaria infection clusters by evaluating temporal trends during 2010-2019 in Korea. Incheon was the most likely cluster (MLC) for all cases of malaria during the total period. MLCs for P. falciparum, vivax, malariae, ovale, and clinically diagnosed malaria without parasitological confirmation were Jeollanam-do, Incheon, Gangwon-do, Gyeongsangnam-do, and Jeollabuk-do, respectively. Malaria was decreasing in most significant clusters, but Gwangju showed an increase for all cases of malaria, P. vivax and clinically diagnosed cases. Malaria overall, P. falciparum and P. vivax seem to be under control thanks to aggressive health measures. This study might provide a sound scientific basis for future control measures against malaria in Korea.
A Report of Chigger Mites on the Striped Field Mouse, Apodemus agrarius, in Southwest China
Authors: Chen Yan-Ling , Guo Xian-Guo , Ren Tian-Guang , Zhang Lei , Fan Rong , Zhao Cheng-Fu , Zhang Zhi-Wei , Mao Ke-Yu , Huang Xiao-Bin , Qian Ti-Jun
Published: December 2021

Based on the field investigations in 91 investigation sites (counties) in southwest China between 2001 and 2019, the present paper reported the chigger mites on A. agrarius mice in southwest China for the first time by using a series of statistical methods. From 715 striped field mice captured in 28 of 91 investigated sites, only 255 chiggers were collected, and they were identified as 14 species, 6 genera in 3 subfamilies under 2 families. Of 715 A. agrarius mice, only 24 of them were infested with chigger mites with low overall prevalence (PM=3.4%), overall mean abundance (MA=0.36 mites/host) and overall mean intensity (MI=10.63 mites/host). The species diversity and infestation of chiggers on A. agrarius were much lower than those previously reported on some other rodents in southwest China. On a certain species of rodent, A. agrarius mouse in southwest China seems to have a very low susceptibility to chigger infestations than in other geographical regions. Of 14 chigger species, there were 3 dominant species, Leptotrombidium sialkotense, L. rupestre and Schoengastiella novoconfuciana, which were of aggregated distribution among different individuals of A. agrarius hosts. L. sialkotense, one of 6 main vectors of scrub typhus in China, was the first dominant on A. agrarius. The species similarity of chigger mites on male and female hosts was low with CSS=0.25, and this reflects the sex-bias of different genders of A. agrarius mice in harboring different chigger species.
A Human Case of Lumbosacral Canal Sparganosis in China
Authors: Fan Jian-Feng , Huang Sheng , Li Jing , Peng Ren-Jun , Huang He , Ding Xi-Ping , Jiang Li-Ping , Xi Jian
Published: December 2021

In this study, we intended to describe a human case of lumbosacral canal sparganosis in People’s Republic of China (China). A 56-year-old man was admitted to Xiangya Hospital Central South University in Changsha, Hunan province, China after having an experience of perianal pain for a week. An enhancing mass, a tumor clinically suggested, was showed at the S1-S2 level of the lumbosacral spine by the examination of magnetic resonance imaging (MRI) with gadolinium contrast. The patient was received the laminectomy from S1 to S2, and an ivory-white living worm was detected in inferior margin of L5. In ELISA-test with cerebrospinal fluid (CSF) and serum samples, anti-sparganum antibodies were detected. He had a ingesting history of undercooked frog meat in his youth. By the present study, a human case of spinal sparganosis invaded in lumbosacral canal at the S1-S2 level was diagnosed in China. Although the surgical removal of larvae is known to be the best way of treatment for sparganosis, we administered the high-dosage of praziquantel, albendazole and dexamethasone to prevent the occurrence of another remain worms in this study.
Autonomic Nervous System Function in Newly Diagnosed Multiple Sclerosis: Association With Lipid Levels and Insulin Resistance
Authors: Hardoňová M. , Šiarnik P. , Siváková M. , Suchá B. , Vlček M. , Imrich R. , Turčáni P. , Havranová A. , Rádiková Ž. , Žitňanová I. , Dean Z. , Penesová A. , Kollár B.
Published: December 2021

Autonomic nervous system (ANS) disorders are common in multiple sclerosis (MS). Previous studies showed differences in insulin resistance (IR) and lipoprotein levels in MS subjects compared to controls. Lipolysis caused by increased sympathetic activity could be one of the possible linking mechanisms leading to dyslipidemia in MS. Our study aimed to evaluate ANS activity in the context of glucose and lipid metabolism in people with MS. We prospectively measured short-term heart rate variability (HRV), fasting lipoprotein concentrations, and calculated IR indices based on plasma glucose and insulin levels during oral glucose tolerance test (oGTT) in 32 patients with MS and 29 healthy controls matched for age, sex and body mass index in our study. There was no significant difference in HRV parameters and lipoprotein levels between MS and controls. A significant positive correlation was found between low/high-frequency power ratio (LF/HF) and triglycerides (r=0.413, p=0.021) in MS subjects but not in controls. A significantly lower whole-body insulin sensitivity index (ISIMat) was found in patients with MS compared to the control group (7.3±3.7 vs. 9.8±5.6, p=0.041). No significant correlations were found between LF/HF and IR parameters. In MS subjects, the positive correlation of LF/HF with triglycerides could reflect the effects of sympathetic activity on lipolysis. Positive correlations of sympathetic activity with increased lipoprotein levels could rather reflect processes associated with immune system activation/inflammation, than processes involved in glucose homeostasis maintenance.
Los microempresarios del altiplano y el capital semilla, una visión desde la antropología empresarial
Authors: Véliz Quispe Tomás , Véliz Gonzales Carol Fabiola
Published: December 2021

La investigación destaca las bases e importancia del capital para los microempresarios del altiplano del Perú al 2020; en un contexto de globalización del capital. El objetivo es describir e interpretar la naturaleza del “capital semilla y cultural” de los microempresarios andinos, desde la perspectiva de la antropología empresarial. La metodología está enmarcada en el paradigma cuantitativo y cualitativo; diseño no experimental y tipo descriptivo; muestra 26 encuestas y 11 testimonios de microempresarios; técnica de encuesta por cuestionario y entrevista. El estudio se realizó en los meses de febrero 2018 a marzo del 2020. Los resultados: El capital de la microempresa del altiplano destaca: 1. Capital semilla (ahorros de trabajo, prestamos familiares, uso de crédito) 2. Capital cultural (valores de reciprocidad, responsabilidad y respeto) 3. Capital simbólico (creencias y rituales el tributo a la tierra con vino o cerveza; símbolos de prosperidad la ruda, flores amarillas y lentejas). Las conclusiones: El enfoque del capital desde la antropología empresarial en el altiplano considera: dimensión económica- semilla, cultural-valores y simbología- rituales forman parte de la filosofía de la microempresa.
Comunicación sobre COVID-19 en Twitter: liderazgo y dialéctica Presidentes de México, España, Estados Unidos
Authors: Del Prado Flores Rogelio , Arévalo-Martínez Rebeca Illiana , Góngora Cuevas Genny Elizabeth
Published: December 2021

El artículo trata sobre la comunicación en redes sociales acerca de la COVID-19 y su impacto en los usuarios y tiene como objetivo analizar los mensajes de los presidentes de tres países (España, México y Estados Unidos) en Twitter a la luz de las categorías de liderazgo integrador y pragmático presentes en su contenido y relacionarlos con la dialéctica positiva o negativa que generan entre los usuarios, con el fin de identificar el impacto que tiene el discurso presidencial de la COVID-19. La metodología es mixta con análisis de contenido de los mensajes y pruebas estadísticas sobre la interacción con usuarios en los tweets emitidos por los presidentes entre el 15 de marzo y 15 de abril 2020 sobre COVID-19 y 1% de los comentarios de los usuarios. Entre los principales hallazgos del análisis de contenido se encuentra que los tres presidentes muestran un liderazgo pragmático. En el análisis de la interacción, en México se observan más favoritos, mientras que en España y Estados Unidos más retweets. Finalmente, los comentarios negativos en los tres países son relacionados con política, mientras que los positivos en México y España son sobre política, salud y economía; y en Estados Unidos sobre economía, política y salud.
Методика определения приоритетных мероприятий по развитию транспортной инфраструктуры
Authors: АРГУНОВ Сергей Владимирович , СУРИН Григорий Дмитриевич
Published: December 2021

Рассмотрены вопросы реализации приоритетных мероприятий по развитию транспортной инфраструктуры. Приоритетность мероприятий определяется на основе концепции ранжирования объектов улично-дорожной сети, по результатам которого каждому объекту присваивается ранг, отражающий его важность среди подобных. Выявлены основные этапы определения наиболее приоритетных объектов транспортной инфраструктуры к реализации, представлены веса связанных объектов капитального строительства. Введено понятие показателя градостроительной необходимости реализации объектов и соответствующих мероприятий. Рассмотрена оценка экономической и бюджетной эффективности от реализации объектов, а также расчет удельных показателей затрат на транспортную инфраструктуру. Установлен конечный показатель ранга объектов и произведено ранжирование по их числовому значению. Разработанная методика и ее применение на практике позволяют определять первоочередные мероприятия по развитию транспортной инфраструктуры и содействовать успешной реализации проектов планировки в целом. Данная методика может использоваться при решении вопросов развития транспортной инфраструктуры не только Москвы, но и других крупных городов.
Оптимизация производства карт для целей формирования программ благоустройства Москвы
Authors: ВОЛОХИНА Оксана Александровна , АСКАРОВ Ришат Ринатович , ПРОНИН Александр Александрович
Published: December 2021

Рассмотрена необходимость применения географической информационной системы специалистами НПЦ "Развитие города" для достижения целей программ благоустройства городской среды. Предложена методика оптимизации работы с использованием возможностей геоинформационной системы QGIS: создание, анализ, хранение, преобразование и обработка пространственных объектов. Представлен механизм, позволяющий оперативно наносить данные на карту максимально автоматизированным способом. Показано расширение функций программы с помощью плагинов, которые добавляют новые возможности в географическую информационную систему и позволяют ускорить процесс создания карты. Продемонстрированы инструменты оформления, создания макетов картографических материалов с последующим их экспортом в различные форматы хранения данных. Полученные с помощью представленной методики карты можно использовать как в печатном, так и в электронном видах.
Modern approaches to the elimination of artifacts of cone-beam computed tomography of the maxillofacial region
Authors: Dolgalev A. A. , Danaev A. B. , Hossain S.J. , Kulikova A. A. , Yamurkova N. F. , Burenchev D. V. , Chagarov A. A.
Published: December 2021

The use of X-ray radiation is the main additional method for complete visualization of hard and soft tissues in dentistry and maxillofacial surgery. Cone-beam computed tomography (CBCT) is of leading importance among other methods. Three-dimensional reformation of CBCT data into a multiplanar or three-dimensional image of anatomical structures allows for a qualitative assessment of the area of interest and to choose the right treatment tactics if necessary. Nevertheless, there are a number of factors or artifacts that lead to distortion, disrupt the image or lead to loss of information during CBCT, in addition, the formation of overdiagnosis is not excluded. Currently, an active search is underway for ways to improve the quality of CBCT images and eliminate artifacts to improve the quality of diagnostics. This review is devoted to the description of the main causes of artifacts and modern methods of their elimination.
Study of the effect of using a hard toothbrush with a high abrasive toothpaste according to profilometry data
Authors: Razumova S. N. , Kozlova Y. S. , Brago А. S. , Razumov N. M. , Glybina T. A.
Published: December 2021

Compliance with oral hygiene is an important aspect of the prevention of dental diseases. But an uncontrolled choice, the use of improperly selected home hygiene products can lead to a number of complications, for example hyperesthesia of dentin. An important aspect of the choice of home hygiene products is their effect on the hard tissues of the tooth.

Aim. To study in the experiment the effect of a hard toothbrush with a high level of abrasiveness of a toothpaste on the change in the enamel surface according to profilometry data.

Materials and methods. Using the device for cleaning teeth, a study was carried out on the roughness of the surface if the enamel of the sample. In research were used the first 3 molars removed for periodontal indications, of which 3 samples of 1×1 cm were prepared. The measurements were carried out using a Senso neox profilometer (Sensofar) with a 3D magnification of 150 at the following time intervals: initial condition of the tooth, 1 week, 1 month, 6 months, 1 year.

Conclusion. When using a hard toothbrush together in combination with a highly abrasive paste, the optimal combination time is not more than 6 months. Further, there is an increase in roughness of enamel surface.
The use of Kollapan in the treatment of periodontal diseases
Authors: Ivaschenko A. V. , Yablokov A. E. , Kolganov I. N. , Shcherbakov M. V. , Bazhutova I. V. , Yablokova A. E. , Chigarina S. E. , Nesterov A. M.
Published: December 2021

Relevance. Before starting the therapeutic treatment of various periodontal diseases, it should be clearly understood that a high-quality treatment is possible only with complex therapy, excluding local irritating adverse factors in the oral cavity, elimination of inflammatory processes in the periodontal tissues, as well as violations of its function. One of the main tasks of the treatment of periodontal diseases is the preservation of the dentition with a single functional system.

Purpose – to assess the use of the drug Kollapan in tooth extraction and treatment of periodontitis.

Materials and methods. The clinical observation group consisted of 40 patients aged 19 to 65 years. The gender ratio was 3 : 2 (60% men, 40% women). The largest percentage of patients (65%) came to the clinic with complex tooth extraction. The remaining 35% – with generalized periodontitis of moderate and mild severity.

Results. Clinical observation showed that in the first group of patients, whose therapy included the use of Collapan, after a complex tooth extraction, physiological healing of the hole was observed, the disappearance of inflammation within 24–36 hours after the surgery
Dental status of geriatric patients with disorder of cognitive functions and their medical and social characteristics
Authors: Podkhvatilina A. S. , Kozhokar A. S. , Margaryan E. G. , Kadzhoyan A. G.
Published: December 2021

Aim: analysis of medical and social characteristics and assessment of the dental status of geriatric patients with cognitive impairment.

Materials and methods. The study was carried out at the Department of Therapeutic Dentistry. We analyzed the responses and laboratory results of 43 patients aged 60–92 years. The main methods used in the study were: questioning (Fox test), sialometry, saliva pH determination, microbiological analysis (of the upper respiratory tract) for fungal microflora.

Results obtained showed that an objective study of the secretory function of the salivary glands according to the method of M.M. Pozharitskaya found that the average rate was 0.2 ± 0.004 ml/min, and the average saliva pH was 5.7 ± 0.04. The medical and social portrait of a geriatric patient indicates that mainly patients with impaired cognitive functions seeking dental treatment and prophylaxis were women, whose average age was 76.03 ± 2.8 years, as a rule, they were representatives of the humanitarian and natural-scientific professions, 75% are married. According to the results of the Fox test, it was found that 60% of patients complained of dry mouth of a different nature. The perception of dry mouth was statistically significantly dependent on gender (P = 0.025) and the presence of chronic diseases (P = 0.004). Women (OR = 1.17, P = 0.026) with chronic diseases (OR = 2.97, P = 0.002) were more likely to suffer from dry mouth.
FAMILY MEMORY OF THE RUSSIA’S CITIZENS IN THE CONTEXT OF ACTUAL SOCIAL CHALLENGES
Authors:   Institute of Sociology of the Federal Center of Theoretical and Applied Sociology of the Russian Academy of Sciences, Moscow, Russian Federation, BARASH RAISA
Published: December 2021

Applying to the sociological data, the author examines the Russians’ perception of the family memory as a source of historical knowledge and proves that the memory about relatives and friends who have become participants and witnesses of the state’s key events seriously “feeds” the emotional citizens’ attitude towards symbols of the state identity and national pride. The actuality of the article is determinated by the global development of digital communication that seriously influences on the interest towards the reconstruction of family history and allows persons today to lift the veil of secrecy over the history of many families. Contemporary internet resources give wide opportunities for many modernized citizens to receive objective historical knowledge about their families. The purpose of this article is to study the specifics of the preservation and reproduction of family memory by the Russia’s citizens. In order to achieve this goal the author implement some research tasks. The author study as the place of the family memory among a number of various historical sources as the demand for family historical knowledge that the persons from different socio-demographic groups has. The special attention is paid to the study of the social media mechanisms that are using in order to reconstruct and reproduce the family memory.
UV kürlenmeli vernik uygulanmış sedir odununun yapay yaşlandırma uygulaması sonrasında bazı yüzey özelliklerinin belirlenmesi
Authors: AYATA Ümit , ÇAKICIER Nevzat , GÜRLEYEN Levent
Published: December 2021

UV kürlenmeli uygulamaların kullanımları, günümüzde teknolojinin gelişmesi ile yaygın bir hale gelmiştir. Bu UV kürlenmeli sistemlerin avantajları da, müşterilerin kullanıma ait çeşitli özelliklerini (uçucu organik bileşik, direnç, vb.) desteklemektedir. Bu uygulamalar birçok sektör açısından tercih edilmekte olunup, uygulama alanlarından biriside ahşap malzeme yüzeyleri olmaktadır. Bu çalışmada, endüstriyel uygulamalara göre Toros sediri (Cedrus libani A. Rich) odunu yüzeylerine UV kürlenmeli parke vernikleri uygulanmış malzemeler üzerinde UV-B 313 lambalarının bulunduğu yapay yaşlandırmaya ortamına maruz bırakılması ile meydana gelen yüzeylerdeki değişiklikler araştırılmıştır. Araştırma sonuçlarına göre; yaşlandırma uygulamaları, parlaklık (20o, 60o ve 85o’de liflere paralel ve dik) değerlerinde ve ışıklılık (L*) değerlerinde azalmalara, kırmızı (a*) ve sarı (b*) renk ton değerlerinde ise artışlar görülmüştür. Buna ek olarak, salınımsal sertlik değerleri 3 kat uygulamada yaşlandırma sonrasında azalırken, 5 kat uygulamasında artmıştır. 504 saatlik yaşlandırma sonunda her iki vernik türünde toplam renk farkı (∆E*) değerleri “farklı renk” kriterini vermiştir. Sonuç olarak, literatürdeki çalışmalarla kıyaslandığında Toros sedirinin UV sistem parke endüstrisinde kullanılabileceği söylenebilir.
Mobilya üretimde kullanılan farklı malzemelerin web madenciliği yöntemleri ile değerlendirilmesi
Authors: SÖZEN Eser , BARDAK Timuçin
Published: December 2021

İnternet günümüzde yaygın olarak kullanılan ve içerisinde birçok alandan faydalı bilgiler bulunduran zengin bir kaynaktır. Web madenciliği ise temelde tüketiciler ve tüketicilerin pazar eğilimleri hakkındaki bilgileri bulmaya yardımcı olan bir alandır. Doğru ve güvenilir bilgi, her endüstri için kritik bir konu haline dönüşmüştür. Firmalar web madenciliği teknikleri ile elde edilen anlamlı bilgiler sayesinde daha doğru kararlar alabilmektedir. Bu çalışmada, E-ticaret web sayfalarında farklı mobilya ürünleri hakkında yapılan yorumlar, Rapidminer yazılımı ile elde edilmiştir. Ahşap ve metal malzemeden üretilmiş mobilyalar hakkında elde edilen veriler, web madenciliği ile değerlendirilmiştir. Bu amaçla günlük hayatta yaygın olarak kullanılan çalışma masası, kütüphane ve sandalye mobilyaları seçilmiştir. Tüm mobilya türleri için ayrı ayrı web ve metin madenciliği ile kelime bulutları oluşturulmuştur. Bu sayede mobilya ürünü üzerine yapılan yorumlardaki anahtar kelimeler görselleştirilmiştir. Çalışma sonuçlarına göre ahşap sandalyelerde “sağlamlık” metal sandalyelerde “oturma” ile ilgili yorumlar öne çıkmıştır. Ahşap ve metal çalışma masalarında “güzel” kelimesi öne çıkarken, ahşap kütüphanelerde “kolay”, metal kütüphanelerde “ofis” ve “paketleme” anahtar kelimeleri ortaya çıkmıştır.
Forming a data ecosystem: international experience of infrastructure asset management
Authors:   National Institute for Strategic Studies, OLIYNYK Danyila
Published: December 2021

Based on the research conducted on the European policy of data ecosystem formation, the feasibility of regulatory alignment of the components of the digital ecosystem model in Ukraine to measure and control the parameters on economic sustainability is substantiated. The article presents the approaches of the EU, international standardization organizations and scientists to understanding the essence of the data ecosystem, identifies factors that impact the complexity of network assets administration on the example of infrastructure assets. Emphasis is placed on ensuring sustainability and assurance of existing network infrastructure assets throughout their lifecycle. The problems of digital transformation related to the increasing strain on all infrastructure systems, which are solved by the model of network infrastructure formation, are outlined. The need to accelerate the introduction of semantic technologies in IoT, in particular artificial intelligence, which expands the possibilities of data analysis and control and support of economic indicators of the state and the creation of added value in production and services, is justified.
Transdisciplinary consolidation of financial technologies with knowledge systems
Authors:   SESE “The Academy of Financial Management”, LYUBICH Oleksandr , STRYZHAK Oleksandr ,   SESE “The Academy of Financial Management”
Published: December 2021

The article describes a cognitive IT technology that provides consolidated interaction with online narrative documents which show various financial technologies. Consolidated interaction is carried out in the process of implementing innovative projects. An aggregative model of consolidated interaction is presented.
Conceptual problems of the development of interdisciplinary research in the field of international economic relations
Authors:   Taras Shevchenko National University of Kyiv, LUTSYSHYN Zoriana
Published: December 2021

In the context of the current Ukrainian realities, given its place, the significance and role in the geo-economic space from the standpoint of economic security the issue of high-quality provision of research in the area of international economic relations and, consequently, training of scientists and researchers in this field is acute. The article discusses the prerequisites and substantiates the need to find a mechanism for improving teaching methods, enhancing the effectiveness of forms and methods of teaching and research based on an interdisciplinary approach, search and development of new theories. The step-by-step algorithm of training / formation of scientists, characteristic features of the current stage of scientific research, communication and cooperation environment, specifics of training doctors of philosophy on the basis of competence approach is analyzed as well as the problems of terminological casuistry, quality of scientific publications, search for topical themes aimed at addressing a number of issues related to increasing the competitiveness of Ukrainian science in the area of international economic relations with a practical focus on strengthening Ukraine's position on the current geoeconomic chessboard. The purpose of the article is to study the prerequisites for reconfiguring the format of scientific research, enriching the research methodology, filling it with interdisciplinary tools.
IMPLEMENTASI 2D BARCODE PADA LABEL PANGAN OLAHAN SEBAGAI KEKUATAN PENGAWASAN BADAN PENGAWAS OBAT DAN MAKANAN (BPOM)
Authors: Dessy Setiawanti
Published: December 2021

Pada saat ini, peredaran produk pangan olahan diwajibkan memenuhi persyaratan keamanan, mutu, dan gizi pangan tersebut. Salah satu dari ketiga elemen tersebut diterapkan ke dalam pangan olahan dalam bentuk label pangan. Keterangan informasi pada label pangan bertujuan untuk menerangkan bahwa informasi yang tertera benar, tidak mudah rusak dan lepas, mudah dilihat dan dibaca melalui Nomor Izin Edar (NIE). BPOM bersinergi kuat dalam pengawasan produk pangan dengan menerbitkan penerapan 2D barcode dalam label pangan sebagai kebijakan untuk mengurangi risiko peredaran produk pangan palsu atau ilegal. Metode penulisan karya ini secara studi pustaka melalui pengambilan data berdasarkan peraturan perundang-undangan yang berlaku serta pelaporan pengawasan terhadap label pangan. Intensifikasi pengawasan produk pangan yang dilakukan oleh BPOM pada sarana ritel dan distribusi banyak menemukan produk Tanpa Izin Edar (TIE), produk kedaluwarsa serta produk rusak. Hasil data yang didapatkan terhadap temuan pengawasan produk pangan lebih banyak ditemukan produk TIE dengan persentase temuan di Sarana Ritel sebesar 52%, sedangkan persentase temuan di Gudang Importir/Distributor sebesar 72%. Dengan penerbitan implementasi 2D Barcode pada label pangan olahan sangat memberikan dampak positif bagi stakeholder meliputi. pemerintah, pelaku usaha dan masyarakat. Penerapan 2D Barcode ini diupayakan mampu membangun intelektual masyarakat untuk menjadi lebih responsif serta cerdas dalam mengolah informasi di masa yang akan mendatang.
Crops' Yield and Roots Response to Soil Phosphorus Distribution Resulting From Long-Term Soil and Phosphate Fertilization Management Strategies
Authors: Nunes Rafael de Souza , Sousa Djalma Martinhão Gomes de , Goedert Wenceslau J. , de Oliveira Luiz Eduardo Zancanaro , Pinheiro Thamires Dutra
Published: December 2021

We investigated labile P and roots distribution in the soil profile and their effect on phosphorus uptake and soybean and corn yield under different tillage systems and phosphate fertilization managements. In a long-term experiment fertilized with triple superphosphate (TSP) or reactive phosphate rock (RPR), where the fertilizer was band-applied in the crop row or broadcasted under conventional tillage (CT) or no-tillage (NT), we evaluated labile P (Bray-1) and root density distribution in depth, and crop yield, biomass production and P uptake by soybean (16th crop) and corn (17th crop). The soil disturbance in CT promoted more homogeneous soil P distribution while in NT there was a strong gradient in depth, with nutrient accumulation in the fertilizer application zone. In general, the average content of P in the 0–20 cm layer was similar for the two soil management systems and for the two application methods, but higher for TSP in relation to RPR. Root distribution of soybeans in NT and corn in both tillage systems showed a strong relationship with soil P distribution. The production of biomass, P uptake and grain yield of soybean in CT was influenced by phosphate fertilization management and generally presented lower performance than in NT, what did not occur for corn possibly due to a better P uptake efficiency compared to that of soybean. Greater stratification on the distribution of soil P and soybean and corn roots in NT did not represent any limitation on the nutrient uptake and yield of these crops, not even in the extreme case where the fertilizer was continuously broadcast on the soil surface. The influence of soil tillage management and phosphate fertilization was more evident in soybeans than corn.
Effect of Sperm Cryopreservation on miRNA Expression and Early Embryonic Development
Authors: Xu Xiaoyu , Li Wanqiong , Zhang Lina , Ji Yazhong , Qin Jiaying , Wang Lu , Wang Mingwen , Qi Lingbin , Xue Jinfeng , Lv Bo , Zhang Xunyi , Xue Zhigang
Published: December 2021

Although sperm preservation is a common means of personal fertility preservation, its effects on embryonic development potential need further investigation. The purpose of this study was to identify key microRNA (miRNA) in cryopreserved sperm and determine the changes of these miRNAs and their target genes during embryonic development using cryopreserved sperm. Moreover, the embryonic development potential of cryopreserved sperm was estimated in assisted reproductive technology (ART), where key miRNAs and target genes were validated in sperm and subsequent embryos. Clinical data of embryonic development from cryopreserved sperm indicated a significant decrease in fertilization rate in both in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) cases, as well as a reduction in blastocyst formation rate in ICSI cases. Meanwhile there was a significant increase in blocked embryo ratio of Day1, Day2, and Day3.5 embryos when frozen-thawed mouse sperm was used, compared with fresh mouse sperm, suggesting a potential negative effect of sperm cryopreservation on embryonic development. From frozen-thawed and fresh sperm in humans and mice, respectively, 21 and 95 differentially expressed miRNAs (DEmiRs) were detected. miR-148b-3p were downregulated in both human and mouse frozen-thawed sperm and were also decreased in embryos after fertilization using cryopreserved sperm. Target genes of miR-148b-3p, Pten, was identified in mouse embryos using quantitative real-time PCR (qRT-PCR) and Western blot (WB). In addition, common characters of cryopreservation of mouse oocytes compared with sperm were also detected; downregulation of miR-148b-3p was also confirmed in cryopreserved oocytes. In summary, our study suggested that cryopreservation of sperm could change the expression of miRNAs, especially the miR-148b-3p across humans and mice, and may further affect fertilization and embryo development by increasing the expression of Pten. Moreover, downregulation of miR-148b-3p induced by cryopreservation was conserved in mouse gametes.
Collagen and Discoidin Domain Receptor 1 Partnership: A Multifaceted Role in the Regulation of Breast Carcinoma Cell Phenotype
Authors: Saby Charles , Maquoi Erik , Saltel Frédéric , Morjani Hamid
Published: December 2021

Type I collagen, the major components of breast interstitial stroma, is able to regulate breast carcinoma cell behavior. Discoidin domain receptor 1 (DDR1) is a type I collagen receptor playing a key role in this process. In fact, collagen/DDR1 axis is able to trigger the downregulation of cell proliferation and the activation of BIK-mediated apoptosis pathway. The aim of this review is to discuss the role of two important factors that regulate these processes. The first factor is the level of DDR1 expression. DDR1 is highly expressed in epithelial-like breast carcinoma cells, but poorly in basal-like ones. Moreover, DDR1 undergoes cleavage by MT1-MMP, which is highly expressed in basal-like breast carcinoma cells. The second factor is type I collagen remodeling since DDR1 activation depends on its fibrillar organization. Collagen remodeling is involved in the regulation of cell proliferation and apoptosis through age- and proteolysis-related modifications.
Production of Succinic Acid From Basfia succiniciproducens
Authors: D’ambrosio Sergio , Alfano Alberto , Cimini Donatella
Published: December 2021

Basfia succiniciproducens is a facultative anaerobic capnophilic bacterium, isolated from rumen, that naturally produces high amounts of succinic acid by fixing CO2 and using fumarate as final electron acceptor. This metabolic feature makes it one of the ideal candidates for developing biotechnological industrial routes that could eventually replace the polluting and environment unfriendly petrochemical ones that are still main sources for the production of this value-added compound. In fact, due to the large number of applications of succinic acid that range from the more traditional ones as food additive or pharmaceutical intermediate to the most recent as building block for biopolymers and bioplastic, increasing demand and market size growth are expected in the next years. In line with a “green revolution” needed to preserve our environment, the great challenge is the establishment of commercially viable production processes that exploit renewable materials and in particular preferably non-food lignocellulosic biomasses and waste products. In this review, we describe the currently available literature concerning B. succiniciproducens since the strain was first isolated, focusing on the different renewable materials and fermentation strategies used to improve succinic acid production titers to date. Moreover, an insight into the metabolic engineering approaches and the key physiological characteristics of B. succiniciproducens deduced from the different studies are presented.
Fragment-Based Quantum Mechanical Calculation of Excited-State Properties of Fluorescent RNAs
Authors: Shen Chenfei , Wang Xianwei , He Xiao
Published: December 2021

Fluorescent RNA aptamers have been successfully applied to track and tag RNA in a biological system. However, it is still challenging to predict the excited-state properties of the RNA aptamer–fluorophore complex with the traditional electronic structure methods due to expensive computational costs. In this study, an accurate and efficient fragmentation quantum mechanical (QM) approach of the electrostatically embedded generalized molecular fractionation with conjugate caps (EE-GMFCC) scheme was applied for calculations of excited-state properties of the RNA aptamer–fluorophore complex. In this method, the excited-state properties were first calculated with one-body fragment quantum mechanics/molecular mechanics (QM/MM) calculation (the excited-state properties of the fluorophore) and then corrected with a series of two-body fragment QM calculations for accounting for the QM effects from the RNA on the excited-state properties of the fluorophore. The performance of the EE-GMFCC on prediction of the absolute excitation energies, the corresponding transition electric dipole moment (TEDM), and atomic forces at both the TD-HF and TD-DFT levels was tested using the Mango-II RNA aptamer system as a model system. The results demonstrate that the calculated excited-state properties by EE-GMFCC are in excellent agreement with the traditional full-system time-dependent ab initio calculations. Moreover, the EE-GMFCC method is capable of providing an accurate prediction of the relative conformational excited-state energies for different configurations of the Mango-II RNA aptamer system extracted from the molecular dynamics (MD) simulations. The fragmentation method further provides a straightforward approach to decompose the excitation energy contribution per ribonucleotide around the fluorophore and then reveals the influence of the local chemical environment on the fluorophore. The applications of EE-GMFCC in calculations of excitation energies for other RNA aptamer–fluorophore complexes demonstrate that the EE-GMFCC method is a general approach for accurate and efficient calculations of excited-state properties of fluorescent RNAs.