bluuebunny/crossref_metadata_2025 huggingface dataset:
Optical Simulation and Development towards Compact Sensor Heads using Deep Frequency Modulation Interferometry
Authors: An Sangmin , Isleif Katharina-Sophie
Published: August 2024

Die Tiefenfrequenzmodulationsinterferometrie (DFMI) bietet eine vielversprechende Alternative zur klassischen Heterodyn-Interferometrie, indem sie die optische Komplexität reduziert und gleichzeitig eine dynamische Auslesung über mehrere Laser-Wellenlängen sicherstellt. DFMI hat auch das Potenzial absolute Entfernung zu messen, indem die optische Laufzeit in die Modulationstiefe enkodiert wird, was diese Technik attraktiv für Hilfssensoren in Gravitationswellendetektoren und für industrielle Anwendungen macht. Diese Studie untersucht DFMI in einem Michelson-Interferometer zur Messung von Oberflächenverformungen mit einem Sensornetzwerk. Wir adressieren Herausforderungen bei der Entwicklung kompakter, drahtloser Sensoren mit kostengünstigen Laserdioden, die unerwünschte Amplitudenmodulationen einführen. Wir bewerten die Effizienz und Phasenfehler von DFMI-Anpassungsalgorithmen bei starker residualer Amplitudenmodulation und zeigen die Notwendigkeit neuer Anpassungsmethoden, um die Fehler selbst bei schwachen Amplitudenmodulationen zu reduzieren. Um den Dynamikbereich eines kompakten Sensors abzuschätzen, simulieren wir ein Michelson-Interferometer mit IFOCAD, um die interferometrischen Signale in Abhängigkeit der Testmassen-Bewegung vorherzusagen. Unsere Ergebnisse zeigen, dass die Verwendung eines Retroreflektors als Testmasse robuste Translationsmessungen auch bei hohen Winkeldynamiken ermöglicht und eine genaue Bewegungserkennung senkrecht zur Laserstrahlachse durch die Nutzung einer Quadrant-Photodiode mit differentieller Wellenfront- oder Leistungsmessung erlaubt. Wir vergleichen diese Ergebnisse mit der Leistung eines Planspiegels als Testmasse.
Impact of dilating forcing amplitudes on a peristaltically driven non-Newtonian fluid in an elastic tube: application to swallowing disorders
Authors: Pandey Sanjay K. , Pandey Anupam K.
Published: August 2024

We investigate the flow dynamics within an elastic tube transporting a power-law fluid, where the tube is subject to a specified external forcing in the form of a progressive traveling wave. The oesophagus is cylindrical in shape and exhibits linear elastic properties. The flow is creeping, and the long wavelength and low Reynolds number approximations are employed for a solution. The relationship between the pressure distribution within the oesophagus and the radial variation of the tube characterizes the behavior of the tube. Findings reveal that the elasticity and the variations in the applied dilating forcing amplitude substantially impact pressure resulting from sinusoidal wave forcing. Notably, even a nominal increase in the inward radial force amplitude for dilatant fluid results in significant pressure changes compared with Newtonian fluid. We also observe a notable distinction between time-averaged volume flow rate and velocity in pseudo-plastic and dilatant forms. Our study also identifies that the radial velocity experiences either attenuation or enhancement due to the fluid’s shear thickening and thinning characteristics. Moreover, our research uncovers a novel dimension by highlighting that in shifting from pseudo-plasticity to dilatancy, the fluid requires higher pressure to propel the bolus toward the hiatus. This observation has important implications, suggesting that feeding a more dilatant fluid to patients with pre-diagnosed swallowing disorders, such as sliding hiatus hernia, is not advisable, fearing increased pressure.
Variation in the development of Neolithic societies atop the Central Anatolian Plateau: recent results from Balıklı
Authors: Goring-Morris A. Nigel , Munro Natalie D. , Özbaşaran Mihriban , Kayacan Nurcan , Ergun Müge , Uzdurum Melis , Yelözer Sera , Kalkan Fatma , Duru Güneş
Published: August 2024

Regional variation in the historic development of agricultural societies in South-west Asia is increasingly apparent. Recent investigations at the wetland site of Balıklı (c. 8300–7900 BC) provide new insights into the initial processes of sedentism in Central Anatolia and the interaction of early communities within local and larger-scale networks. Located near major obsidian sources, excellent architectural preservation and faunal and botanical records at Balıklı suggest cultural connections to the upper Middle Euphrates region, yet inhabitants of the site do not appear to have participated in the wider South-west Asian obsidian-exchange networks and largely relied on wild resources.
Processing-Microstructure-Mechanical Property Paradigm in Hot Rolled Ti-6Al-4V Alloy
Authors: Paliwal Deepak , Jha Sumit , Raturi Abheepsit , Ghosh Atasi , Bandyopadhyay Soumya , Pandey Vivek Kumar , Anoop C. R. , Narayanan P. Ramesh , Mukherjee Rajdip , Gurao Nilesh Prakash
Published: August 2024

The effects of hot rolling temperature and subsequent cooling at different cooling rates on the microstructure, texture, and mechanical properties of α + β titanium alloy Ti-6Al-4V were studied using a battery of structural and mechanical characterization tools. To this end, Ti-6Al-4V samples were subjected to a rolling reduction of 50 % below the β-transus (750°C and 850°C) and near the β-transus (950°C) temperature followed by water quenching and air cooling. Detailed electron back scatter diffraction provided information on the fraction, morphology, and orientation of the alpha and β-phases for different processing conditions and bulk texture analysis provided information on the orientation relationship at the macroscale. Mechanical properties, like hardness and modulus, were determined at different length scales using the Vickers microhardness experiment, instrumented microindentation, and nanoindentation. Hot rolling at sub β-transus temperatures (750°C and 850°C) leads to the equiaxed morphology of the α-phase and the absence of a Burgers orientation relationship (BOR) with the β-phase, whereas near the β-transus, hot rolling leads to the multi-variant lamellar morphology of the α-phase and a strong BOR with the β-phase for both the cooling conditions. Hot rolling at 850°C followed by water quenching showed an optimum combination of indentation hardness and modulus. This has been primarily attributed to the relatively low kernel average misorientation of the basal-prism-oriented grains compared with the prism-pyramidal oriented grains after indentation. The basal oriented grains are both elastically and plastically harder compared with the prism-oriented grains that are elastically soft but plastically hard. The orientation specific indentation hardness property is reflected in the microhardness property for sub β-transus deformed samples. A clear processing-microstructure-texture-mechanical property paradigm in the context of variant selection and distinct cooling rates for hot rolling of Ti-6Al-4V is established.
A morte esconde-se sob a beleza dos túmulos: fotografias do Arquivo da Irmandade São Miguel e Almas de Porto Alegre
Authors: Dillmann Mauro
Published: August 2024

Este ensaio visual tem a intenção de apresentar algumas fotografias do Cemitério da Irmandade São Miguel e Almas (ISMA) de Porto Alegre, que se encontram no Arquivo da própria instituição. Inaugurado em 1909, o cemitério, privado e católico, logo atendeu aos anseios de uma parcela da população ávida por valorizar e eternizar a memória de seus antepassados em grandes jazigos, em túmulos que se tornavam um patrimônio material que não apenas representavam a morte, mas também possuíam a intenção simbólica de escondê-la sob a beleza dos túmulos.
O Retorno do Encoberto como Paródia: Inflexões no Teatro das Memórias Sociais na Atualidade
Authors: Corrêa Alexandre Fernandes
Published: August 2024

Reflexão sobre a preservação dos patrimônios culturais e das memórias sociais na atualidade. Análise crítica das políticas do patrimônio cultural e natural na sociedade brasileira contemporânea, através de aproximações teóricas dos Estudos Culturais com a Psicanálise, Mitologia e a Etnologia comparada. Esse estudo tenta responder mais especificamente a seguinte questão: quais os alcances políticos de um trabalho de ação cultural voltado para a reabilitação das memórias sociais dos marginalizados?
A força do sagrado no patrimônio imaterial: agenciamentos religiosos e políticos na restauração da Gruta de Oxum da Praia da Alegria, Guaíba
Authors: Sant'Ana Maria Helena
Published: August 2024

Analisa como uma luta pela restauração de uma Gruta de Oxum, localizada na Praia da Alegria na cidade de Guaiba, RS, produz agenciamentos que entrecruzam uma visão religiosa a processos de patrimonialização, de disputas políticas e de religiosidades. Contexto que situa cruzamentos e desencontros entre a lógica de salvaguarda do bem público e as formas de heranças e transmissão dos sagrados e dos “axés” dos terreiros afrobrasileiros. Interpreta-se que a demanda por sua revitalização religiosa através da adesão à categoria patrimônio imaterial frente à Prefeitura Municipal produziu a Gruta de Oxum como um objeto fronteira, na disputa de seu destino material e simbólico, com múltiplas possibilidades de significação patrimonial. Neste caso, compreende-se como a defesa do patrimônio imaterial vem a ser incorporada na perspectiva encompassadora da visão religiosa e das práticas que a atualizam e que se cruzam de forma tensa com a posição dos governantes municipais.
Modifying of surface properties and structural characteristics of low energy argon beam irradiated methylcellulose/TiO2 nanocomposite films
Authors:   Department of Physics, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia, Altuijri R. , Atta A. ,   Physics Department, College of Science, Jouf University, P.O. Box: 2014, Sakaka, Saudi Arabia, Abdeltwab E. ,   Physics Department, College of Science, Jouf University, P.O. Box: 2014, Sakaka, Saudi Arabia, Abdelhamied M. M. ,   Charged Particles Lab., Radiation Physics Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo, Egypt
Published: August 2024

Flexible polymeric nanocomposites MC/TiO2 films, which consisting of titanium dioxide (TiO2) and methyl cellulose (MC) were fabricated in this research for applied in coating devices. The successful manufacturing of MC/TiO2 sheets were verified by FTIR, SEM and XRD methods, which demonstrated a uniform distribution of TiO2 in MC. Additionally, the chemical bonds of MC and TiO2 contribute for the broadening and decreasing of MC in the peaks intensity of XRD and FTIR with increasing TiO2, indicating the successful incorporation of TiO2 in MC. The impacts of argon beam bombardment on MC/TiO2 composites using cold cathode source with fluencies (2.5×1015, 5×1015 and 7.5×1015 ions/cm2 ). The contact angle, work of adhesion and surface free energy of MC/TiO2 were determined as a function of ion irradiation. The water contact angle is decreased from 70.32o to 43.34o by increasing ion fluence from 2.5×1015 ions/cm2 to 7.5×1015 ions/cm2 , while the surface free energy is enhanced from 38.83 mJ/m2 to 64.17 mJ/m2 . The collected data confirmed that the surface wettability of the irradiated MC/TiO2 films were improved to be can usage in coating and printing applications
Hydrothermal synthesis of La0.5Sr0.5MnO3 nanostructures for enhanced CO oxidation
Authors:   R&D Laboratory, Department of Physics, Excel Engineering College (Autonomous), Namakkal – 637 303, Tamil Nadu, India, Priyatharshni S. , Sivakumar P. ,   R&D Laboratory, Department of Chemistry, Excel Engineering College (Autonomous), Namakkal – 637 303, Tamil Nadu, India, Prabhu N. ,   R&D Laboratory, Department of Physics, Excel Engineering College (Autonomous), Namakkal – 637 303, Tamil Nadu, India, Karthikraj C. ,   R&D Laboratory, Department of Physics, Excel Engineering College (Autonomous), Namakkal – 637 303, Tamil Nadu, India, Gowtham M. ,   Department of Aeronautical Engineering, Excel Engineering College (Autonomous), Namakkal – 637 303, Tamil Nadu, India
Published: August 2024

This study focuses on the synthesis and characterization of La0.5Sr0.5MnO3 (LSMO) perovskite nanostructures via the hydrothermal method and their catalytic performance evaluation in CO oxidation. Structural analysis using techniques like XRD, FE-SEM, FTIR, and Raman spectroscopy analysis verified the development of LSMO nanostructures exhibiting a rhombohedral phase configuration. The catalytic activity of the annealed LSMO nanostructures was assessed, demonstrating significant CO conversion efficiency attributed to structural modifications enhancing catalytic performance. These findings highlight the potential of LSMO perovskite nanostructures as efficient catalysts for CO oxidation.
Theoretical exploration of novel alkannin derived D-π-A conjugated organic dyes as efficient sensitizer in dye-sensitized solar cells
Authors:   Department of Physics, Jamal Mohamed College (Autonomous) (Affiliated to Bharathidasan University), Tiruchirappalli-620020, Tamil Nadu, India, Mary Josephine X. , Raj Muhamed R. ,   Department of Physics, Jamal Mohamed College (Autonomous) (Affiliated to Bharathidasan University), Tiruchirappalli-620020, Tamil Nadu, India, Sathyanarayanamoorthi V. ,   Department of Physics, PSG College of Arts and Science (Autonomous),  Coimbatore-641014, Tamil Nadu, India
Published: August 2024

The advancement of cost-effective, highly efficient sensitizers plays a crucial role in the progress of dye-sensitized solar cells (DSSCs). Employing density functional theory (DFT) and time-dependent density functional theory (TD-DFT), a range of metal-free organic dyes with D - π - A configuration, featuring different donor and acceptor groups, have been investigated to enhance the effectiveness of sensitizer dyes. We developed metal-free organic dyes (Ak1-Ak6) with a D - π - A structure through structural modifications of alkannin reference dye. Calculations were conducted to assess the electronic and optical properties, along with key parameters such as short-circuit current density (Jsc) and open-circuit voltage (Voc), including light-harvesting efficiency (LHE), electronic injection-free energy (ΔG inject), and regeneration driving forces (ΔG reg) of the designed dyes. The outcomes of this study offer valuable insights for the design of highefficiency DSSCs.
Structural, optical and dielectric properties of (AZT) aluminum doped zinc titanate nano-composites
Authors:   Department of Physics, GSS, GITAM Deemed to be University, Bangalore562163, India, Srinivas Y. , Prasad N. V. K. ,   Department of Physics, GSS, GITAM Deemed to be University, Bangalore562163, India, Naresh U. ,   Dept. of Physics, PVKK Institute of Technology, Anantapur-515001, India, Basha D. B. ,   College of Computer and Information Sciences, Majmaah University, Al’Majmaah, K.S.A-11952
Published: August 2024

Aluminum-doped Zinc Titanate (AZT) AlxZn1-xTiO3 ( for x= 0.20,0.40,0.60,0.80) nanoparticles are synthesized through low temperature hydrothermal method and their physical properties such as structure, surface, energy gap and dielectric characteristics were investigated using X-ray diffraction (XRD), Field Emission Scanning Electron Microscopy (FESEM), Transmission Electron Microscopy (TEM), UV-visible spectroscopy and impedance analysis. XRD analysis indicated structural transformation of tetragonal phase for samples of x = 0.20 to 0.60 and some secondary phases for x=0.80. It was found that lattice constants of the sample decrease with increasing aluminium content. The morphology of nano-composites, as evidenced by FESEM and TEM imaging, displayed the formation of nano-spheres and nano-rods. The impedance and dielectric modulus analysis for the current samples revealed their dielectric behaviour, microstructure and conduction procedure. However negative dielectric property was seen in nano-composite with x=0.60. All samples with x ranging between 0.2 to 0.8 displayed high ac-electrical conductivity at 1 MHz frequency. These samples are well suitable for charge storage capacitors and as perfect absorbers.
The Alteration Level of VEGF of Colon Cancer Cell After Induction with Mandarin Orange (Citrus Reticulata) Peel Ethanol Extract
Authors: Astuti Yoni , Zuliana Utami Anisa , Suharto Agus , Yano Yoshihiko , Aristyaning Putri Wahyu
Published: August 2024

The natural ingredient-based therapy extracted from various plants is assumed more tolerable to cancer patients’ bodies than synthetic drugs. To tell successful novel cancer therapy, an indicator is needed to confirm the result. VEGF is a pro-angiogenic factor that leads the cancer cells’ invasion to another organ and is associated with high mortality in patients. Hence, the VEGF level is widely used as one of the successful cancer therapy indicators. Purposed of research elucidated the effect of Mandarin orange peel ethanol extract (EEKJM) to improve the reduction of VEGF levels in colon cancer in vitro. This study was an experimental posttest and control group design to analyze different level of VEGF on cancer cells at end of the study.  Research began with the preparation of EEKJM followed by a cytotoxic extract test using the MTT assay method. Furthermore, the measurement of VEGF levels by the VEGF ELISA kit protocol. One Way ANOVA was performed to analyze data.Results showed the cytotoxic test of the EEKJM and doxorubicin against WiDr cells was 240 g/ml and 1.59 µg/ml. VEGF levels showed decreasing after being induced with EEKJM and doxorubicin with doses ½ IC50 and ¼ IC50. Conclusion: EEKJM was able to reduce VEGF levels and viability of WiDr colon cancer cells. The advantages are as much as initial evidence of the ability of the orange to treat cancer even though further animal studies or evidence of a pathway of decrease of the VEGF or other signals are required.
Influence of the forest mosaic on functional diversity of earthworms (Oligochaeta, Lumbricidae) (on the example of forest-steppe Ob region in Novosibirsk area)
Authors: Ермолов С.А.
Published: August 2024

В разнотравно-папоротниковых сосняках и березово-осиновых папоротниковых лесах, наиболее характерных для лесостепного Приобья Новосибирской области, проведено исследование населения дождевых червей семействаLumbricidae с учетом лесной мозаичности. Подробный анализ структуры комплексов дождевых червей позволил выделить конкретные виды и жизненные формы, биотопически приуроченные как к определенному типу леса, так и к лесному микросайту. В сосняках в основном преобладают азиатские виды, в березово-осиновых лесах – космополиты. Различия в населении лесных микросайтов по показателям плотности населения и биомассы червей более выражены в окнах, чем в подкроновых и межкроновых пространствах, особенно в сосняках. При изучении населения дождевых червей в валежнике для каждого типа леса выявлены характерные особенности структуры комплексов: в сосняках неполночленные валежные комплексы червей дополняют почвенные, в березово-осиновых лесах валежники являются обособленным микросайтом с полночленным комплексом дождевых червей.

In pine and birch-aspen forests that are typical for forest-steppe Ob region in Novosibirsk area we conducted a study of earthworm populations (Lumbricidae) with taking into account forest mosaic. A detailed analysis of the structure of earthworm complexes made it possible to identify concrete species and living forms that are biotopically distributed to both a certain type of forest and a forest microsite. Asian species mainly predominate in pine forests, cosmopolitans in birch-aspen forests. Differences in the population of forest microsites in terms of earthworm population density and biomass are more pronounced in the forest gaps than in the spaces under tree crown and between tree crown, especially in pine forests. Studying the population of earthworms in the deadwood we revealed the characteristic features of complexes structure for each type of forest: in pine forests incomplete deadwood earthworm complexes complement soil ones, in birch-aspen forests, deadwood is a specific microsite with a full-complete earthworm complex.
El efecto de la educación en los ingresos en Argentina a través de un estudio econométrico
Authors: Caro Norma Patricia , Avalis Francisca
Published: August 2024

Los efectos piel de oveja se refieren a las ganancias (o ingresos) de los individuos asociadas a la obtención de un diploma. Con el objetivo de determinar la relación entre educación y la prosperidad económica de los individuos, se encuentra evidencia de efectos piel de oveja asociados a la finalización de los sucesivos niveles educativos en Argentina. Se utilizan los datos de la encuesta Permanente de Hogares del Instituto Nacional de Estadísticas y Censos (INDEC, 2021), en Argentina, 15199 registros correspondientes al tercer trimestre de 2021. Se aplican dos modelos econométricos, uno general donde se explican los ingresos en función del efecto de las variables que representan escolarización, experiencia, variables de control y las que indican los títulos obtenidos y otro modelo sin las variables que representan el título. Los resultados obtenidos, una vez controlados los efectos de la escolarización, muestran la importancia de las titulaciones como factor explicativo de los retornos de la educación. Los efectos de piel de oveja hallados parecen validar, al menos parcialmente, la hipótesis credencialista. En términos generales la finalización de sucesivos niveles de educación superior, incrementa los ingresos.
Percepciones del cuerpo académico sobre los fines de la Educación Universitaria. Algunos resultados preliminares para una pregunta de fondo
Authors: Espejo Leupin Roberto , Cárdenas Artigas Karin , Romo López Verónica
Published: August 2024

Este artículo presenta las percepciones sobre los fines de la educación universitaria de un conjunto de 48 docentes de una universidad privada chilena. Para esto se revisó la literatura especializada y se estableció una selección individual de posibles fines formativos de la educación universitaria por cada persona investigadora, los cuales fueron luego socializados y discutidos para definir un conjunto propuesto de siete conceptos con base al criterio de las personas investigadoras. Los conceptos fueron presentados al grupo de docentes solicitando su jerarquización según importancia a través de un cuestionario en línea. El estudio se enmarca en un paradigma positivista, con un diseño no experimental descriptivo, comparativo y transeccional. Los datos fueron analizados a partir de la importancia otorgada por el profesorado a cada concepto, ubicándolos en una zona central y dos zonas periféricas a través de un análisis de conglomerados. Los resultados muestran la centralidad que se otorga al desarrollo del pensamiento crítico, la actitud ética y la autonomía, siendo conceptos más periféricos el compromiso social, las competencias ciudadanas, la autodeterminación y las competencias técnicas de la profesión. Estos resultados varían al considerar distintos niveles de experiencia docente y tipo de disciplina, con excepción del desarrollo del pensamiento crítico que mantiene su posición central. Se destaca cómo este tipo de descripciones puede ser una herramienta para fortalecer procesos de desarrollo docente y la necesidad de complementar estos resultados con técnicas cualitativas y estudios longitudinales.
Acciones innovadoras mediadas por tecnologías digitales en educación secundaria: un análisis en función del sexo y la edad del profesorado
Authors: Mercado Borja William Enrique , Calle Álvarez Gerzon Yair , Barrera Navarro Juancri Rusbel , Mosquera Mosquera Carlos Enrique
Published: August 2024

Las prácticas pedagógicas y su relación con el uso de acciones innovadoras mediadas por Tecnologías de la Información y las Comunicaciones (TIC), inciden en el desarrollo de competencias digitales del cuerpo docente. El objetivo del estudio es presentar una descripción y un diagnóstico multivariado sobre acciones innovadoras con tecnologías digitales en docentes de educación secundaria, tomando como referencia las variables de género y edad. El estudio es cuantitativo y de tipo no experimental, descriptivo y correlacional. Fue llevado a cabo a través de un instrumento con 5 dimensiones: resistencia al cambio, confianza, utilidad percibida, la facilidad de uso e intención de uso; aplicado a una muestra de 165 docentes de educación secundaria de Colombia. Los resultados fueron obtenidos a partir de análisis descriptivos e inferenciales mediante las pruebas no paramétricas Test U Mann-Witney y Test Kruskal-Wallis. Estas muestran una percepción favorable en cuanto al uso de acciones innovadoras mediadas con TIC por parte del profesorado. Frente a las variables analizadas, se dilucida que en todas las dimensiones existen diferencias significativas en función del sexo y la edad, excepto entre la dimensión utilidad percibida y la edad.
A stochastic loss given default model of Hungarian residential mortgages
Authors: Várgedő Bálint
Published: August 2024

The paper analyses the Loss Given Default (LGD) rates of residential mortgages, using a model based on stochastic collateral value. The implementation of the model is based on exponential Ornstein-Uhlenbeck processes fitted to the Hungarian regions' house price indices. According to the model results, in case of a mortgage with a 80% loan-to-value ratio at origination, the expected LGD is around 30–40%, depending on the region. The highest LGD rates are estimated for villages, while the lowest rates are expected in Budapest and cities in the middle of the country. The range of the regional differences can reach 7 percentage points. According to the LGD Risk index based on the aggregated model, the LGD risk profile of recently issued mortgages has improved significantly since 2009 in Hungary.

Due to the strong negative relation between the house prices and mortgage default rates, the expected return on defaulted collateral value tends to be low. The results could be relevant for credit institutions in their mortgage origination decisions and enhance analysis of lending processes and the associated risks.
М’ЯСНИЙ ХЛІБ З РОСЛИННИМИ ІНГРЕДІЄНТАМИ
Authors: Агунова Л. В. , Глушков О. А. , Кумпан А. В.
Published: August 2024

Розглянута можливість використання борошна червоної сочевиці і меленого пажитнику при виробництві м’ясних хлібів. В серії досліджень органолептичних і функціонально-технологічних показників модельних фаршевих систем встановлено, що при внесені запропонованих рослинних добавок зростає показник вологозв’язуючої здатності на 21 % при внесенні 5 % борошна червоної сочевиці і на 4 % при внесенні 1,0 % меленого пажитника. Натомість значення показників граничного напруження зсуву і активної кислотності падають. Граничне напруження зсуву у зразках із борошном червоної сочевиці зменшується максимально на 90 Па, а у зразках із пажитником на 34 Па, показник рН зменшується на 0,7 і 0,39, відповідно. Сенсорні характеристики модельних зразків характеризувались незначним падінням за рахунок зменшення соковитості і ущільнення структури. Смак і запах залишились гармонійними, властивими даному виду продукції. Керуючись результатами органолептичної оцінки запропоновано вносити 5 % борошна червоної сочевиці (замінюючи 2 % крохмалю картопляного і 3 % яловичини І сорту) та 0,5 % меленого пажитника (замінюючи 0,5 % сала бокового). Доведена доцільність збільшення масової частки доданої води при кутеруванні на 6 % при внесені даних добавок. Такий технологічний прийом сприяє збільшенню виходу готової продукції на 4 %. Досліджено показники якості експериментального зразка м’ясного хліба з борошном червоної сочевиці і меленим пажитником. Встановлено, що вони повністю відповідають вимогам нормативної документації, а отже використання рослинних інгредієнтів у технології м’ясних хлібів дозволить розширити асортимент і раціонально використовувати сировину тваринного походження.
Dental and microbiological status of COVID-19 convalescent patients with simple marginal gingivitis
Authors: Lyamin A. V. , Vinnik A. V. , Postnikov M. A. , Vinnik S. V. , Popov N. V. , Alekseev D. V.
Published: August 2024

The pattern of dental morbidity in the population of the Russian Federation evidences about a high incidence of inflammatory periodontal diseases, which varies based on patient age and comorbidity. The negative age-related dynamics of dental health emphasizes the problem of concomitant pathology and requires constant monitoring of risk factors for inflammatory periodontal diseases. Insufficient attention is paid to endogenous risk factors, such as neurodystrophic disorders, diseases of the cardiovascular system, leukemia, anemia, gastrointestinal tract diseases, infections, etc. At the same time, the growth of “new” infections (HIV-infection, HCV-infection, Ebola fever, new coronavirus infection) is recorded with elevating level of other infectious diseases. The aim of the study is to assess dental and microbiological status of COVID-19 convalescent patients. A survey of 100 patients diagnosed with simple marginal gingivitis (ICD-10 code: K 05.10) was carried out consisting of the following groups: main group — 75 COVID-19 convalescent patients, control group — 25 COVID-19-negative subjects. All individuals underwent microbiological diagnostics for gingival groove contents and an assessed dental status. The index assessment was performed using the simplified Green-Vermillion Oral Hygiene Index (OHI-S), the PMA index (Parma) and the gingival papilla blood flow index (PBI). In the laboratory, the collected material was seeded onto expanded list of dense nutrient media. The identification of isolated microorganisms was carried out using MALDI-ToF mass spectrometry. Our analysis of the index assessment in both groups showed that the average values of the indices 1 month after the diagnosis of new coronavirus infection (ICD-10 code: U07.1) in main group are higher than in control group. Based on the results of a microbiological study, significant differences in the frequency of microbial species isolation were identified for 12 species. Thus, it is important to develop approaches to predicting development of chronic gingivitis and its exacerbation in COVID-19 patients.
Identification of specific IgG class antibodies to certain flaviviruses in the population of the Republic of Guinea
Authors: Krivosheina E. I. , Kartashov M. Yu. , Naidenova E. V. , Ushkalenko N. D. , Svirin K. A. , Bah M. B. , Nourdine I. , Boumbaly S. , Ternovoi V. A.
Published: August 2024

One of the most common arboviruses in the world are representatives of the genus Orthoflavivirus (family Flaviviridae). On the territory of the Republic of Guinea, the circulation of such representatives of this family as the yellow fever virus (YFV), West Nile virus (WNV) and dengue virus (DENV) has been confirmed. The aim of the study was to determine the level of specific IgG class antibodies to YFV, DENV and WNV in residents of various landscape– geographical zones of the Republic of Guinea by the ELISA method. Materials and methods. For the study, a panel of 1559 blood serums from practically healthy people was compiled, which were collected in all landscape and geographical zones of the Republic of Guinea. The detection of specific IgG class antibodies to DENV and WNV was carried out with commercial diagnostic drugs, and for YFV — with an experimental ELISA test system based on an analogue of the third domain of protein E obtained at the State Research Center for Virology and Biotechnology “Vector” of Rospotrebnadzor. Results. When testing blood sera in 28.5% (95% CI: 26.3–30.7) of cases, IgG antibodies to YFV, to DENV — in 11.8%, (95% CI: 10.3–13.5) and to WNV — in 27.0% (95% CI: 24.8–29.3) were detected. Antibodies to three viruses simultaneously (YFV, DENV and WNV) were detected in 30 cases, to YFV and DENV — 14, YFV and WNV — 44, DENV and WNV — 56. Conclusion. The detection of antibodies to WNV and DENV confirms the fact of the continued circulation of these pathogens in the territory of the Republic of Guinea, which poses a health risk to the local population. A detailed study of the molecular genetic and antigenic properties of flaviviruses circulating in this area will allow the development of more specific diagnostic tools.
Methyl orange sorption on octadecylamine-modified iron oxide magnetic nanoparticles
Authors: Tianhui Liang , Aga-Tagieva Sayara , Omelyanchik Alexander , Xiaozhou Zhang , Lu Hong , Levada Katerina , Rodionova Valeria , Magomedov Kurban
Published: August 2024

This study investigates the sorption of 2-methyl orange dye onto octadecylamine-modified iron oxide magnetic nanoparticles (ODA-IONPs). The synthesized ODA-IONPs exhibit remarkable sorption capacity, reaching 800 mg/g at the nanoparticle concentrations ranging from 5 to 10 mg/g and pH of 2–8. The sorption process demonstrates rapid kinetics, achieving 90% of maximum sorption within 0.5 min. Thermodynamic analysis showed that sorption process is spontaneous and endothermic, as indicated by negative ΔG and positive ΔH values. The pseudo-second-order and Langmuir models best describe the sorption kinetics at 293 K (R² 0.99). Compared to other adsorbents, ODA-IONPs show superior MO removal capacity under a wider pH range. The influence of nanoparticle concentration, pH, and temperature on sorption efficiency is systematically explored, with optimal conditions identified at 10 mg/L ODA-IONPs and pH 6. Furthermore, the feasibility of nanoparticle reusability for sorption purposes is assessed. These findings underscore the potential of ODA-IONPs as efficient sorbents for wastewater treatment and environmental remediation applications.
Mechanosynthesis of pentiptycene-based polyesters and polycarbonates
Authors: Al-Ithawi Wahab A.K. , Al-Sammarraie Eman S. A. , Baklykov Artem V. , Platonov Vadim A. , Altobee Aqeel M.K. , Glebov Nikita S. , Khasanov Albert F. , Kovalev Igor S. , Nikonov Igor L. , Kopchuk Dmitry S. , Zyryanov Grigory V.
Published: August 2024

Iptycenes are common building blocks for the small-molecules or polymer-based chemosensors and fluorophores. In addition, iptycene derivatives are widely presented in polymers of intrinsic microporosity (PIMs) as materials for the separation and purification technologies. In this manuscript we wish to report a mechanochemical approach to pentiptycene-based polyesters and polycarbonates as, possibly, new representatives of PIMs. Our approach involves the polycondensation reaction between 5,7,12,14-tetrahydro-5,14:7,12-bis([1,2]benzeno)pentacene-6,13-diol (pentiptycene-6,13-diol) and triphosgene or oxalyl chloride under ball-milling conditions. The obtained polymers were characterized by means of 1H NMR- and IR-spectroscopy. As the last step, the fluorescence “turn-off” response of pentiptycene-6,13-diol and two pentiptycene-based polymers towards nitroanalytes (2,4-dinitrotioluene (DNT) and 2,4,6-trinitrophenole (picric acid, PA)) was investigated, and Stern-Volmer constants as high as 1o4 M–1 were observed.
ROBUST TOPOLOGY OPTIMIZATION USING MULTI-FIDELITY VARIATIONAL AUTOENCODERS
Authors: Gladstone Rini Jasmine , Nabian Mohammad Amin , Keshavarzzadeh Vahid , Meidani Hadi
Published: August 2024

Robust topology optimization (RTO), as a class of topology optimization problems, identifies a design with the best average performance while reducing the response sensitivity to input uncertainties, e.g., load uncertainty. Solving RTO is computationally challenging as it requires repetitive finite element solutions for different candidate designs and different samples of random inputs. To address this challenge, a neural network method is proposed that offers computational efficiency because (i) it builds and explores a low dimensional search space, which is parametrized using deterministically optimal designs corresponding to different realizations of random inputs, and (ii) the probabilistic performance measure for each design candidate is predicted by a neural network surrogate. This method bypasses the numerous finite element response evaluations that are needed in the standard RTO approaches and with minimal training can produce optimal designs with better performance measures compared to those observed in the training set. Moreover, a multi-fidelity framework is incorporated to the proposed approach to further improve the computational efficiency. Numerical application of the method is shown on the robust design of L-bracket structure with single point load as well as multiple point loads.
Gene Expression Analysis of the Early Flowering 6 Homologues in Apricot Reveals Their Potential Role in Developmental Stages
Authors: Kıyak Ali
Published: August 2024

In higher plants, regulation of gene expression and chromatin formation occurs by histone methylation and demethylation. Genes encoding JmjC-JmjN domains belong to the histone demethylase family and have an important role in the regulation of plant growth and development. Early Flowering 6 (AtELF6), which encodes the JmjC-JmjN domain in Arabidopsis thaliana, is a demethylase that regulates growth and development as well as the transition to flowering, but it has not been identified in apricot so far. In this study, two genes homologous to AtELF6 were identified for the first time in apricot. Gene expression analysis by RT-qPCR revealed that both ELF6 homologs were expressed in 12 different developmental stages of three different tissues. The fact that both homologues were expressed, especially in the flower bud, suggested that they play a role in the transition to flowering, similar to Arabidopsis thaliana. In summary, the information obtained from this study will provide a unique resource for understanding the role of ELF 6 in apricot growth and development, as well as for future functional characterization studies for the manipulation of the flowering transition.
Yüksek Teknoloji İhracatında Karşılaştırmalı Rekabet Gücü Analizi: Öncü ilk 40 Ülke Örneği
Authors: Öztemiz Handan
Published: August 2024

İhracata dayalı büyüme stratejileri çerçevesinde ekonomik büyüme ve kalkınmanın önemli araçlarından birisi teknoloji üretimi ve ihracatıdır. Teknolojinin günlük yaşamın bir parçası olduğu günümüzde hemen hemen tüm ülkeler teknoloji üretimi ve ihracatıyla uğraşmaktadır. Bu kapsamda teknoloji üretimi ve ihracatında ayrıştırıcı unsurun, yüksek teknolojili ürün üretimi ve ihracatı olduğu söylenebilir. Bu çalışmada yüksek teknoloji ihracatında öncü 40 ülke örneklem olarak belirlenmiş, ulaşılan en güncel verilerle 2012- 2019 yılları arası ülkelerin sektördeki rekabet güçleri Açıklanmış Karşılaştırmalı Üstünlükler Endeksi ve Simetrik Açıklanmış Karşılaştırmalı Üstünlükler Endeksi ile incelenmiştir. Araştırma sonucunda yüksek teknolojili ürün ihracatında Çin ve Çin özel yönetim bölgesi Hong Kong’un başta olmak üzere Asya ülkelerinin karşılaştırmalı üstünlüğe veya diğer ifade ile rekabet gücüne sahip olduğu; AB üye ülkelerinden ise Fransa, Macaristan ve Çekya dışında karşılaştırmalı üstünlüğü sürdüren ülkenin olmadığı belirlenmiştir. Ayrıca ABD’nin de içinde yer aldığı araştırma örnekleminde yer alan 22 ülkenin karşılaştırmalı üstünlüğe sahip olmadığı tespit edilmiştir
A repeated strike loading organ culture model for studying compression-associated chronic disc degeneration
Authors: Li Baoliang , Chen Xu , Chen Hongkun , Zhang Fu , Li Jianfeng , Zhu Zhengya , Tang Tao , Gao Manman , Li Nianhu , Ma Liang , Zhou Zhiyu
Published: August 2024

Mechanical stress has been viewed as one of the key risk factors in accelerating the intervertebral disc degeneration process. The goal of the present study was to employ a repeated strike loading bovine caudal disc system to elucidate the pathophysiological impacts of cumulative mechanical stress on the disc. The discs in the model groups were subjected to two different mechanical stresses: one strike loading or repeated strike loading. The following indices were analyzed: histological morphology, glycosaminoglycan release, disc height, cell viability, apoptosis-related protein expression, and catabolism-related gene expression. Both mechanical stress modes induced degenerative changes in the discs by day 11, such as clefts and delamination of the annulus fibrosus; they increased glycosaminoglycan release. Cell viability was significantly decreased and catabolic gene expression was significantly up-regulated in the degenerative loading group and repeated strike loading group by day 9. These alterations remained evident in the annulus fibrosus tissue of the repeated strike loading group on day 11. Our data suggests that the repeated strike loading model adopted in this study could lead to degenerative changes in the disc organ model. Annulus fibrosus cells displayed a more noticeable response to mechanical stress damage and a slower recovery process, suggesting that the annulus fibrosus serves as a pivotal factor in disc degeneration due to mechanical stress injuries. The study also indicates that due to the gradual self-repair of intervertebral disc cells after injury, it is necessary to apply repeated strike loading on the disc at specific intervals when researching the repair of chronic disc injuries.
The Thai Folk Game “Jik Sen” has Become a Recreational Sport for Older People in Senior Citizen Schools
Authors: Tongterm Tachapon , Chimphali Khanittha , Pongthanu Metawut , Pengseesang Thanyaporn , Kaewma Jeeranan , Namboonlue Sarocha
Published: August 2024

Objectives. The purposes of this study were to: 1) develop an exercise program incorporating the Thai recreational sport “Jik Sen” for older people in senior citizen schools; 2) investigate the effects of the exercise program incorporating the Thai recreational sport “Jik Sen” on the physical fitness of older people in senior citizen schools; and 3) assess the satisfaction level of older people with the exercise program incorporating the Thai recreational sport “Jik Sen”.
Materials and methods. This was a two-group experimental study including the experimental group of 17 people (65.53 ± 3.43 years) and the control group of 17 people (65.76 ± 3.60 years). The participants in this study were healthy individuals aged 60 years and above, who were actively engaged in the elderly school program. They were selected using a purposive sampling method and subsequently assigned them to the experimental and control groups using a matching method based on BMI. The research tools consisted of the exercise program, which incorporated the Thai recreational sport “Jik Sen” developed by the research team, and the Senior Fitness Test (SFT). For a period of 8 weeks, the experimental group involved in an exercise regimen comprising 60 minutes of daily training in the Thai recreational sport “Jik Sen”, with a frequency of 3 days per week. The control group was instructed to maintain their normal daily routine and did not participate in any physical activities or exercise programs during the experiment. The data were analyzed using mean, standard deviation, percentage, and t-test. 
Results. 1) The exercise program incorporating the Thai recreational sport “Jik Sen” for older people in senior citizen schools can be appropriately used to promote exercise and sports in elderly schools in Thailand. The IOC value was 0.97. 2) A significant difference was observed in the mean scores of the 8-foot up-and-go test between the pre-experimental (mean = 7.94, S.D. = 1.34) and post-experimental (after 8 weeks) (mean = 6.70, S.D.= 0.79) periods for the experimental group at the level of 0.05. The mean scores of the 8-foot up-and-go test between the control group (mean = 7.84, S.D. = 1.16) and the experimental group (mean = 6.70, S.D. = 0.79) were also found to be significantly different at the level of 0.05. 3) The experimental group expressed high levels of satisfaction with the exercise program involving the Thai recreational sport “Jik Sen” for older people in senior citizen schools, with a mean score of 4.62 ± 0.51 points.   
Conclusion. The exercise program incorporating the Thai recreational sport "Jik Sen" can effectively enhance the dynamic balance of older individuals in senior citizen schools. Furthermore, it has been shown to facilitate social interaction, improve cognitive abilities including thinking and planning skills, and promote enjoyment.
Проблема эпистемической ответственности и ее психофизиологические основания
Authors: Адамов Михаил Сергеевич
Published: August 2024

В статье анализируется понятие «эпистемической ответственности» как способности субъекта воспринимать себя агентом познавательного процесса, доверяющим собственным познавательным способностям, а также вырабатывающим самостоятельно правила достижения и критерии успешности своей познавательной деятельности. С развитием когнитивных наук, а также совершенствованием современных технологий нейровизуализации появилась возможность изучения психофизологических коррелятов «эпистемической ответственности» в головном мозге человека. Однако очевидны трудности, связанные с формализацией этой эпистемической и одновременно этической категории, а также с убедительностью обоснования наличия такого рода коррелятов в силу разницы между теоретичностью эпистемологического и этического методологического аппарата и физической природой головного мозга, требующей эмпирического обоснования выносимых суждений, в том числе, в обнаружении психофизиологический коррелятов эпистемической ответственности. Тем не менее, в статье предпринимается попытка обоснования возможности обнаружения таковых с целью понимания взаимосвязи между процессами в мозге человека и его способностью к ответственному интеллектуальному поведению. Такое обоснование призвано обеспечить эмпирический базис «ответственности», позволяющий более или менее беспристрастно оценивать когнитивные способности субъекта как заслуживающие доверия в достижении «надежного» знания.
Acute Ischemic Stroke in a Patient with Metastatic Gastric Cancer after Ramucirumab Chemotherapy
Authors: Kim Sumin , Lee Sorae , Sunwoo Jun-Sang
Published: August 2024

Ramucirumab is a vascular endothelial growth factor (VEGF) receptor-2 inhibiting monoclonal antibody for the treatment of gastric cancer, non-small cell lung cancer, colorectal cancer, and hepatocellular carcinoma. Some VEGF inhibitors are known to increase the risk of ischemic stroke; however, their association with ramucirumab remains controversial. To the best of our knowledge, only two cases of ischemic stroke following ramucirumab treatment have been reported worldwide. We herein present the first case of acute cerebral infarction secondary to ramucirumab in Korea.
Delayed Post-hypoxic Leukoencephalopathy after Carbon Monoxide Intoxication Improved by High-dose Steroid Treatment
Authors: Lee Hak in , Oh Eungseok
Published: August 2024

Delayed post-hypoxic leukoencephalopathy (DHPL) is a demyelinating syndrome characterized by acute onset of neuropsychiatric symptoms within days to weeks following apparent recovery from coma after a period of prolonged cerebral hypo-oxygenation. The majority of DPHL cases are associated with carbon monoxide intoxication. There is no specific treatment, and the prognosis is usually poor. However, we present a case of DHPL patient with akinetic mutism, parkinsonism, stool and urine incontinence, and severe cognitive impairment improved after treatment with high-dose steroid therapy.
Cushing’s Disease Complicated with Multiple Thrombotic Phenomena Following Inferior Petrosal Sinus Sampling
Authors: Yoon Bo Hye , Koo Bon Gook , Kang Yoomin , Ha Sang Hee
Published: August 2024

Cushing’s syndrome is an endocrinologic disorder that occurs due to an excessive secretion of adrenal cortex-stimulating hormones or an overproduction of cortisol in the adrenal glands. Patients present with a variety of clinical symptoms such as obesity, hypertension, impaired glucose tolerance, and cardiovascular complications have been known for major contributors to the mortality. The inferior petrosal sinus sampling (IPSS) test is a useful diagnostic tool for identifying the source of Cushing’s disease. This procedure involves process of collecting samples through venous access and is generally considered safe. Here, we present 44-year-old patient diagnosed with Cushing’s disease presenting pulmonary thromboembolism and multiple embolic infarctions following IPSS.