bluuebunny/crossref_metadata_2025 huggingface dataset:
SURGICAL MANAGEMENT OF EXTRA-ARTICULAR PROXIMAL TIBIA FRACTURE USING MINIMALLY INVASIVE TECHNIQUE WITH LOCKING COMPRESSION PLATE: AN OBSERVATIONAL STUDY
Authors: Maheshkumar Pandya Srikant , Kumar Gautam Rakesh , Singh Manjeet , Singh Chahal Jashandeep
Published: May 2022

Methods: This study evaluated the outcome of 23 patients with total 24 proximal tibia fractures, treated with Minimally Invasive Plate
Osteosynthesis using LCP from 13 March 2020 – 30 September 2021 at MMIMSR, Mullana.
Results: There were 17 males and 6 females, with mean age of 51 years. RTA was the most common cause of trauma (65%). Most common fracture
type as per AO classication was 41-A3.1 (41.7%). The average injury to surgery interval was 2.1 ± 1.4 days. The mean duration of surgery was
98.91 ± 16.5 minutes. Average follow-up period was 20.5 weeks. Union was seen in duration of 12 ± 3.9 weeks. Full weight bearing was achieved
by 12.9 ± 4.5weeks. American Knee Society Score is subdivided into knee score and function score. At 6 months follow-up, the mean Knee Score
was 86.7 ± 11.5 and the mean Functional Score was 88.1 ± 13.2. The mean range of motion at 108.5° ± 16.8° at 6 months. There was 1 instance of
supercial infection, 3 instances of knee stiffness and 1 instance of non-union.
Conclusion: MIPPO technique for management of extraarticular proximal tibia fractures using LCP leads to excellent clinical and functional
outcome.
COVID-19 DILEMMA: EARLY SEVERE HEMOLYTIC JAUNDICE IN NEWBORN BORN TO MOTHER WITH SARS-COV-2 INFECTION IN PREGNANCY
Authors: Gupta Aashish , Chowdhry Mohit , Gupta Vidya , Balan Saroja
Published: May 2022

COVID-19 has been associated with hemolytic anemia in pediatric as well as adult age group. However, very little is known about the clinical
course and immune responses in newborn born to a mother who contracted SARS-CoV-2 infection during pregnancy. Previously, few cases of
autoimmune hemolytic anemia with SARS-CoV-2 infection due to the cytokine storm or through molecular mimicry has been found. Through this
report, we would discuss about the SARS-COV-2 reactive antibodies as a potential etiology of severe early hemolysis leading to severe neonatal
hyperbilirubinemia in a neonate born to a mother with SARS-CoV-2 infection.
A STUDY OF OUTCOME OF MINIMUM 1 YEAR FOLLOW UP OF JOINT REPLACEMENT IN VARIOUS GOVERNMENT SCHEME (A STUDY OF 35 CASES)
Authors: S. Parmar Dipak , Amin Vihang
Published: May 2022

The hip joint is the most important joint of the body as it enables a person to assume various postures. Diseases of this joint are always alarming
because if untreated, produces serious disability, for this reason various methods of management of hip diseases have been devised, but failure of
conventional management in advanced stages of hip diseases like AVN, osteoarthritis, rheumatoid arthritis, congenital subluxation or dislocation,
bone tumor etc. have brought a new surgical era of Total Hip Replacement (THR).
The knee joint is the largest articulation in the body. Also this is a main weight bearing joint of the body. The usual degenerative changes due to
advancing age most commonly affect this joint. Diseases of this joint are alarming because if untreated it produces more and more pain and
disability, for this reason various methods of management of knee joint ailments have been devised, but failure of conventional management in the
advanced stage of knee arthritis have brought a new surgical era of total knee replacement.
Arthroplasty is an operation to restore pain free motion to a joint and function to the muscles, ligaments and other soft tissue structures that control
the joint. There has been an explosion in this eld of knowledge in recent years.
Objectives: The aim of this work is to study outcomes of 1 year follow-up of joint replacement (THR+TKR) under government scheme and to
study in terms of Pain relief,Range of motion, Functional improvements- To measure the functional outcomes, Complications - To evaluate short
term as well as long term complication rate.
Materials and Methods: This is the retrospective study operated with total hip arthroplasty and total knee arthroplasty with atleast 1 year follow
up of cases belonging to various age groups and having various pathologies of hip joint and knee joint and treated with uncemented THR and
cemented TKR were assessed in respect to midterm follow up. Cases were assessed in respect to postoperative results of short and long term follow
up with proforma and post operative radiographs at department of Orthopaedics, Guru Gobind Singh Govt. Hospital, Jamnagar
Results: TKR- Average functional score is 91.15 with 12 patients having score >90. Maximum score is 100 and minimum score is 5. Average knee
score is 93.5 with maximum score 99 and minimum score 88.
THR- Almost all patients were walking with normal gait. Almost All (100%) patients were pursing their daily activities either normally or with
minor modication in life style.82% had excellent Harris hip score.
DIAGNOSIS OF CANDIDA FROM PERIPHERAL BLOOD FILM: A CASE REPORT
Authors: Sodhatar Kinnari , Modi Ankit , Shah Chintan , Patel Umang
Published: May 2022

Candidemia is the most frequent invasive fungal infection in hospitalized patients. This report describes the case of a nine month old baby on whom
three colostomy were performed due to intestinal obstruction. After third colostomy, patient presented with fecal peritonitis. Peripheral blood lm
examination revealed yeast form of candida. Subsequently candida species was isolated on blood culture and subculture on cornmeal agar
and biochemical tests conrmed the presence of Candida albicans. A diagnosis of fungal infection based on the peripheral blood lm has a
potential to lead to early diagnosis and prompt treatment of a life threatening infection.
THE ROLE OF TRANEXAMIC ACID IN REDUCING BLOOD LOSS DURING ELECTIVE CAESAREAN SECTION IN A TERTIARY CARE CENTRE
Authors: Shiva Shiva , Sinha Chitra
Published: May 2022

Introduction: The reduction of maternal mortality is one of the indicators under Goal 3- Ensure healthy lives and promote well-being for all at all
ages of Sustainable Development Goals. It seeks to reduce global MMR to less than 70 per 100 000 live births by 2030. A leading cause of maternal
mortality is Post-partum Haemorrhage (PPH). Hence, it is imperative that any improvement in maternal mortality rate must address the issue of
Post-partum Haemorrhage.
Post-partum Haemorrhage (PPH) is dened as the amount of blood loss in excess of 500 ml following the birth of the baby (World Health
Organization). The clinical denition, which is more practical, states, any amount of bleeding from or into the genital tract following the birth of the
baby up to the end of the puerperium, which adversely affects the general condition of the patient evidenced by the rise in pulse rate and falling
blood pressure, is called Post-partum Haemorrhage.
Aim: The present study is aimed to determine the clinical efcacy of tranexamic acid in reducing blood loss during elective caesarean section in
Patna Medical College and Hospital, Patna.
Type of study: Prospective study
Study period: 1 year (January 2020 to December 2020)
Materials and Methods: This is a prospective study conducted in Obstetrics and Gynaecology department at Patna Medical College and Hospital,
Patna. 100 female patients scheduled for elective caesarean section are enrolled for the present prospective study, which was carried out from
January 2020 to December 2020. The patients were randomly divided into 2 groups. 50 patients received 1g intravenous tranexamic acid 10
rd
minutes before skin incision in addition to active management of 3 stage of labour and the other 50 patients were kept under the active
rd
management of 3 stage of labour only.
Result: In the present study, the amount of blood loss was found to be signicantly low (mean 537 ml) in the tranexamic acid group as compared to
the control group (608 ml), the difference was statistically signicant (p-value 0.001). The mean fall in haemoglobin level was also less (0.61
mg/dl) in the group which received the tranexamic acid as compared to the control group (1.07 mg/dl), the difference was statistically signicant (p-
value 0.001). Postpartum haemorrhage (blood loss more than 1000 ml) was observed in 1 patient in the control group and no case of PPH was
observed in the study group.
Conclusion: To reduce blood loss following caesarean section, TXAmay be safely recommended in addition to Oxytocin.
AN OBSERVATIONAL, RETROSPECTIVE STUDY ON THE IMPACT OF CORTICOSTEROIDS AND THEIR OUTCOMES IN COVID-19 PATIENTS
Authors: Bomma Durga , Laxmi Jyothi Sakilam , Chrysolite Gongati Nissi , Babu Sethu , Raphel Daniel Mary
Published: May 2022

Background: Corticosteroids were a topic of controversy during the ongoing pandemic. Safety and effectiveness of corticosteroids still remains
questionable in COVID-19.
Aims and objectives: To determine the reduction of morbidity and mortality, to assess the length of hospital stay, secondary infections and adverse
events in COVID-19 patients receiving corticosteroids.
Settings and Design:Aretrospective, observational study was performed at Krishna Institute of Medical Sciences (KIMS) hospital, Secunderabad.
Materials and Methods : A total of hundred RT-PCR positive patients aged >18 years were included in the study, of which, 75 patients received
corticosteroids and 25 patients did not. All the necessary information was collected for a period of 6 months from January, 2021-June, 2021 through
the subjects' medical records.
Statistical analysis used: Statistical SPSS version 2.0 software by carrying out chi-square test and independent t-test.
Results: Patients in the corticosteroids group showed 80% recovery and 20% mortality, while corticosteroid-free patients showed 100% recovery.
From the overall sample, 15% (15) fatality cases were reported in corticosteroid group out of which 80% were male, 67% aged 61-80 years, and
40% and 33% had HTN and HTN + DMII as co-morbidities respectively. No signicant difference was observed in mean hospital LOS between
corticosteroid (10.76 ± 5.26) and corticosteroid-free (9.92 ± 6.04) patients. 13% of secondary infections and 12% of adverse events were observed
in the corticosteroids group.
Conclusions: The study concludes that COVID-19 patients who received corticosteroids showed no survival benet. It reveals that corticosteroids
have no impact on hospital LOS. Secondary infections and adverse events were more pronounced in the corticosteroids group.
NEUROVASCULAR HYPERCOAGULABILTY IN COVID-19-A PICTORAL ESSAY
Authors: Moorthy Prashant , Bruce Jeban Chella , Meganathan Samaran , Jawahar Dinesh Babu
Published: May 2022

Acute stroke is a medical emergency during the COVID-19 pandemic as COVID-19 being a hypercoagulable state. COVID-19 present mostly
with respiratory system related symptoms, while others present with atypical gastrointestinal, cardiovascular, or neurological manifestations. Here
we present a series of three patients with COVID-19 that presented with acute stroke [1].
Methods: Hospital PACS was searched for COVID RTPCR positive patients who presented with weakness. Patients who had imaging suggestive
of stroke and PCR-conrmed COVID-19 infection were included in the study. Informed consent was obtained.
GORHAM STOUT DISEASE:A RARE CASE REPORT
Authors: Meena Ishwar , Gomes Nihal
Published: May 2022

Background: Disappearing bone disease -Gorham Stout disease a unparallel case of Unknown Origin . Medical condition of Bones, which does
not have any specic etiology. An extremely rare disorder, which causes the proliferation of endothelial channels and can lead to results and
disappearance of bone. Here sudden bone osseous matrix is destroyed and also lymphatic vascular structures up proliferated and further leads to
excessive regional osteolysis.With a variating clinical presentation and very often is diagnosed as benign disease which further spreads to an
unclear prognosis.Mainly diagnosed by single and various combinations like clinical features, histological ndings and radiological ndings.
Many therapeutic options have managed to provide certain efcacy, but most effective therapeutic option is still controversial without a certain
standard treatment protocol
Case presentation:A case of disappearing bone disease affecting the proximal femur, pelvis, sacrum in a 45 year old male has been described here.
Clinical features of the disease are pain , swelling of the affected region, functional impairment. In this case the diagnosis was made after the
pathological fracture of femur. Based on radiological and clinical ndings. Considering stabilisation as an important aspect internal xation that
was done followed by Bisphosphonates used for progession control and is now being currently followed up with no cessation of disease. But
internal xation has prevented complete severe disability.
Conclusion:Hereby given that conrmed ethiopathology of disappearing bone disease is not completely veried and further study is still needed to
effectively treat and provide intervention. But the need for every physician to know of it's presence, promptly direct a patient towards the right
direction and we are hence reporting this for it's rarity.
COMPARATIVE EVALUATION OF MICROLEAKAGE OF 5 , 7 & 8 GENERATION DBA’S: AN IN VITRO STUDY
Authors: Patil Deepu , Anvesh Sabbinani , C Shashidhar , Halli Basavaraj , Sardar Poonam , Neeruganti Karthika , Omar Kashif Mohammed
Published: May 2022

Aim: th th th
The purpose of the study was to evaluate microleakage of 5 , 7 & 8 generation DBA'S.
Methodology: th
On 45 extracted premolars, Class V cavities were prepared and divided into 3 groups according to the generation of DBA used. Group I uses 5
th th
generation, Group II uses 7 generation, and Group III uses 8 generation DBA's, followed by composite restoration, which were then
thermocycled at 5 & 55 ± 2°C for 1000 cycles and submerged in methylene blue (2%) and observed under stereomicroscope.
Results: th th th
Microleakage was highest in 7 generation DBA followed by 5 and minimal in 8 generation DBA. The 8th generation DBA had
statistically signicant results in respect to minimal microleakage in comparison to other generation DBA's.
Conclusion: th th th
8 generation DBA(Tetric N-Bond Universal) showed least microleakage compared to 5 and 7 generation DBA's.
VITAMIN D3 STATUS OF WOMEN WITH OSTEPOROSIS ATTENDING A TERTIARY CARE HOSPITAL
Authors: Joseph Mini , Beegum M Saboora
Published: May 2022

Introduction: Vitamin D deciency is a major health problem worldwide. Vitamin D is essential for the calcium homeostasis & skeletal
metabolism. Vitamin D deciency is a risk factor of osteoporosis. In women, Vitamin D status is of particular importance. Women in the early
menopausal period and post-menopausal period are exposed to greater risk of developing bone abnormalities & other associated disorders due to
low Vitamin D levels. The study was conducted for a period of one year in 100 women aged 40-60 years with osteoporosis. SerumMethodology:
vitamin D3, ionized calcium, phosphorus and ALP were determined. Serum Vitamin D level & BMD were signicantly reduced in studyResult:
population with a mean of 20.18± 10.04 SD & -3.25 respectively. Vitamin D deciency was found in 72% of the study population. Signicant
association was obtained between Vitamin D level & BMD. There is high prevalence of Vitamin D deciency & low Bone MineralConclusion:
Density among women with osteoporosis. Vitamin D level & BMD are variables that depends on each other. In women with osteoporosis Vitamin
D status is of particular importance. So, it is essential to maintain adequate levels of vitamin D levels among them.
EPIPLOIC APPENDAGITIS: AN UNCOMMON CASE OF ACUTE ABDOMINAL PAIN WITH CHARACTERISTIC IMAGING FINDINGS.
Authors: C Shreyas , Chauhan Ankita , Sharma Sanjeev
Published: May 2022

Introduction: th th
Epiploic appendagitis is an uncommon cause of abdominal pain and is frequently undiagnosed. Obese men in their 4 and 5 decade
of life are most affected. It generally mimics other serious causes of acute abdomen and thus the denitive diagnosis relies on cross-sectional
imaging primarily computed tomography ndings. Most often the condition is caused due to torsion of an epiploic appendage or spontaneous
venous thrombosis of a draining appendageal vein. Appendices epiploicae are small (0.5-5 cm long), fat lled pouches of peritoneum projecting
from the external surface of colon and are supplied by blood vessels that protrude through the bowel wall. They are present commonly over distal
colon particularly numerous at the rectosigmoid junction.
Case: We are reporting a case of 42 years old male patient, who presented to the surgical OPD at Dr. RPGMC Tanda with chief complaint of acute
abdominal pain localized in the left iliac fossa with tenderness in the region. The ultrasonography report was inconclusive and the patient was
further evaluated using biochemical investigations and contrast enhanced CT of the abdominopelvic region. The CECT revealed fat dense ovoid
shaped lesion in the left iliac fossa with surrounding fat stranding and hyperdense rim suggestive of intraperitoneal focal fat infarction. The
condition was managed conservatively with empirical antibiotics and analgesics.
Conclusion: Epiploic appendagitis is a self-limiting disease but persistence of symptoms or recurrence requires surgical management with
laparoscopic appendage excision. The anatomical and surgical knowledge of epiploic appendagitis is very important to raise awareness about this
clinical condition and to manage it appropriately.
STUDY OF DHS VERSUS CANNULATED CANCELLOUS SCREWS IN PAUWELS TYPE II AND III FRACTURE NECK FEMUR IN YOUNG ADULTS
Authors: Kumar Ranjeet , Kumar Shailendra
Published: May 2022

Fracture neck of femur is a specic type of intracapsular hip fracture
and is called unsolved fracture [1]. Fracture neck of femur are
associated with low energy falls in the elderly[2]. In younger pateints
sustaining a femoral neck fracture, the cause is usually high energy
trauma such as a substantial height or motor vehicle accidents [3].
Young pateints with femoral neck fractures will require treatment with
emergent open reduction internal xation.[4] Vertically oriented
fractures pauwel type 2 or 3 are more common in younger and high
energy trauma pateints. With displaced fractures in younger
pateints,the goal is to achieve anatomic reduction through emergent
open reduction internal xation.[5] . Avascular necrosis and nonunion
increase risk factor with increased initial displacement and failure to
obtain an anatomic reduction.[6]. Internal xation is less invasive, can
preserve the femoral head, and the hip function is better after healing
[7]. However, orthopedic surgeons are often perplexed by
postoperative complications of internal xation, such as avascular
necrosis, non-union, implant failure, and reoperation [8,9]. Achieving
an anatomic reduction and stable xation are imperative, other factors
such as timing of surgery, role of capsulotomy and method of xation
remain debatable . Femoral neck fractures with a vertical orientation
have been associated with an increased risk of failure as they are both
axial and rotation unstable and associated with higher rates of
nonunion compared to the more horizontally oriented fractures
sparking debate over the most effective internal xation device. Singh
et al in their study concluded that DHS is a better implant than CC
screw in management of fracture neck femur in young adults in
pauwels type II and III in terms of functional outcome but
complication rate does not depend on the implant selection.
NEW ONSET HYPERTENSION IN POST COVID-19 RECOVERED PATIENTS: A CASE SERIES FROM A TERTIARY CARE HOSPITAL IN EASTERN INDIA
Authors: Mukherjee Rishav , Sanghai Rishav , Bikash Naiya Subhendu , Lyngdoh Lamsaka , Bhattacharya Raja
Published: May 2022

Coronavirus Disease -19 (Covid-19) is a global challenge due to its catastrophic impact on healthcare demographics worldwide. Post Covid
Syndrome is a new clinical entity that has emerged as a concern in recent times. It is dened as the presence of some persistent symptoms like
fatigue, cognitive impairment and sleep disturbances in patients even after four weeks of recovery from Covid-19. Recent medical literature has
hinted on Post-Covid vascular complications and our study has supplemented it by reporting new-onset hypertension in a series of eight patients
within four weeks of recovery from laboratory proven Covid-19. None of the patients had pre-existing hypertension, cardiac disease, renal
abnormalities or any history of long term steroid intake. These patients presented to the fever clinic with initial symptoms of fever, sore throat, mild
cough and fatigue. `They were managed conservatively at home but one of the patients required hospital admission due to hypoxia.All the patients
recovered within ten days of presentation and weekly follow-up visits were scheduled for six weeks at Post-Covid Recovery clinic. At the clinic,
some of them complained of persistent headaches, occasional palpitations or prolonged fatigue. Examination incidentally revealed consistently
elevated blood pressure in all the eight patients, even those who did not have any post covid symptoms. They were advised on antihypertensive drug
therapy and lifestyle modications after six week of routine follow-up and home monitoring. It is proposed that the close binding of the virus with
Angiotensin Converting Enzyme-2 (ACE2) can lead to decrease in the serum enzyme levels, which in turn inhibit the protective pathway of the
Renin-Angiotensin-Aldosterone (RAAS) axis. It might lead to imprudent rise in Angiotensin-2 and thereby blood pressure. Hypertension and its
concomitant effect on target organ damage is a well known risk factor for increased mortality and morbidity among hospitalized Covid-19 patients.
The development of hypertension and other cardiovascular manifestations in the post covid-19 recovery phase warrants further research to
understand the molecular mechanisms, early identication and timely intervention to reduce incidence of adverse cardiovascular events in such
patient cohorts.
Designrhetorik
Authors: Smolarski Pierre
Published: May 2022

Design ist wirkungsintentionales Gestalten und profitiert daher sowohl als praktische Kunst wie auch als begleitende Theorie von der Rhetorik. Designrhetorik gibt der Praxis eine Sprache, der Theorie Argumente aus der Rhetorikgeschichte und verankert die Fragen der Designwirkung interdisziplinär.
utb+: Leser:innen erhalten zusätzlich zum Buch ein Video, das einen Überblick und eine Erläuterung über die zentralen Begriffe der Designrhetorik anhand eines aktuellen Beispiels (Klimaprotestbewegung) bietet.
Die Geschichte des Terrorismus
Authors: Hof Tobias
Published: May 2022

Gruppen wie der Ku-Klux-Klan, die Irish Republican Army, die Rote Armee Fraktion oder der Islamische Staat tragen damals wie heute dazu bei, dass das Thema Terrorismus und dessen Bekämpfung stets präsent sind.
Tobias Hof gibt in seinem Lehrbuch einen historischen Überblick zum komplexen Phänomen des Terrorismus, dessen Varianten sowie dessen Bekämpfung. Er zieht dabei mithilfe anschaulicher Beispiele und aktueller Bezüge einen chronologischen Bogen vom Tyrannenmord in der Antike über die Entstehung des „modernen“ Terrorismus zur terroristischen Gewalt im Zeitalter der Weltkriege bis hin zum transnationalen Terrorismus im 21. Jahrhundert.
A cryptic powdery mildew (Golovinomyces hieraciorum sp. nov.) on Hieracium and Pilosella (Compositae)
Authors: Guan Guan-Xiu , Liu Shu-Yan , Braun Uwe , Qiu Peng-Lei , Liu Jian , Zhao Feng-Yun , Tang Shu-Rong , Li Jia-Ni , Nguyen Van-Ninh
Published: May 2022

The Golovinomyces cichoracearum complex is morphologically highly variable and causes powdery mildew on a wide range of Compositae, including Hieracium spp. and Lapsana communis. A comprehensive phylogenetic analysis of Golovinomyces, published in 2013, revealed that G. cichoracearum s. str. was confined to Scorzonera and Tragopogon spp. as hosts (Compositae, tribe Lactuceae, subtribe Scorzonerinae). To clarify the phylogeny and taxonomy of Golovinomyces on Hieracium spp. (Compositae, tribe Lactuceae, subtribe Hieraciinae), which is common in Asia and Europe, morphology and phylogenetic analyses of ITS + 28S rDNA sequences were conducted for 57 powdery mildew specimens of Hieracium spp. and Lapsana communis. Golovinomyces on Hieracium spp. in Asia and Europe, previously referred to as G. cichoracearum, is a previously undescribed, cryptic species, which is described here as Golovinomyces hieraciorum sp. nov.. Since a sequence retrieved from a powdery mildew on Lapsana communis in Switzerland clustered in sister position to the G. hieraciorum clade, numerous German specimens identified as G. cichoracearum were included in the present examinations. All the re-examined collections of “G. cichoracearum” on L. communis were misidentified, and were shown to belong to Neoërysiphe nevoi or Podosphaera ergerontis-canadensis.
Characterization of Stemphylium spp. associated with tomato foliar diseases in Algeria
Authors: Bessadat Nabahat , Hamon Bruno , Bataille-Simoneau Nelly , Colou Justine , Mabrouk Kihal , Simoneau Philippe
Published: May 2022

Leaf blight and spot caused by Stemphylium spp. and Alternaria spp. are the most common destructive tomato diseases in north-western Algeria. During 2018 growing seasons, more than 30% of samples collected from plants grown in greenhouses or open fields were infected with Stemphylium. Initial symptoms were small, multiple, irregular to oval, yellow leaf spots, which enlarged to brown lesions later. In these lesions, Stemphylium mostly co-occurred with Alternaria spp. Twenty nine Stemphylium isolates were characterized based on morphological features, and multi-locus phylogenies using ITS, gpd, and cmdA genomic loci. Five Stemphylium species (S. lycopersici, S. gracilariae, S. eturmiunum, S. vesicarium, S. lycii) were associated with tomato leaf spot, of which S. lycii is a new report for tomato. Pathogenicity tests on healthy 2-months-old tomato seedlings reproduced symptoms similar to those observed in tomato crops. The tested fungus isolates differed in pathogenicity. Two isolates of S. lycopersici were more aggressive than those of the other species, causing major lesions on tomato plants. The five identified Stemphylium species are reported for the first time as new pathogens for tomato in Algeria, and S. lycopersici, S. gracilariae, S. eturmiunum, and S. lycii as new species of Algerian mycoflora.
Rutin-stevioside and related conjugates for potential control of grapevine trunk diseases
Authors: Buzón-Durán Laura , Langa-Lomba Natalia , González-García Vicente , Casanova-Gascón José , Sánchez-Hernández Eva , Martín-Gil Jesús , Martín Ramos Pablo
Published: May 2022

Flavonoids and phenolic acids play roles in grapevine defence against pathogens causing grapevine trunk diseases (GTDs). Rutin is a major flavonoid in vegetative organs of the grapevines, and this compound, unlike other flavonoids, is non-toxic and non-oxidizable. Rutin was assayed in vitro and in vivo against two Botryosphaeriaceae taxa. The limited bioavailability of this compound was circumvented by conjugation with stevioside, a glycoside obtained from Stevia rebaudiana. Clear synergistic effects were observed for the stevioside-rutin adduct, resulting in EC50 and EC90 values of 306.0 and 714.9 μg·mL-1 against Neofusicoccum parvum and 241.6 and 457.8 μg·mL-1 against Dothiorella viticola. In greenhouse experiments, moderate inhibition of N. parvum growth and complete inhibition of D. viticola were observed. These inhibitory effects were greater than those of ferulic acid, which has been considered the most effective phenolic acid against GTDs. Conjugation with stevioside provided solubility enhancement of rutin, paving the way to the design of glycopesticides based on rutin-rich plant extracts as promising antifungals against GTDs.
Mechanisms of resistance to powdery mildew in cucumber
Authors: TEK Mumin Ibrahim , CALIS Ozer
Published: May 2022

Podosphaera xanthii causes powdery mildew of cucumber, and is associated with significant yield and quality losses. Development of resistant or tolerant varieties is the most effective and eco-friendly strategy for powdery mildew management. An important host resistance mechanism is based on the recognition of conserved resistance genes, resulting in durable resistance. To determine powdery mildew resistance mechanisms in cucumber, total RNAs were isolated from the powdery mildew resistant cultivar Meltem, the tolerant line VT18, and the susceptible local variety Camlica. Expression levels of nine genes in these plants were analysed by Reverse Transcription Polymerase Chain Reaction (RT-PCR). The host reactions were assessed using microscope observations of stained specimens. Serine/threonine (STN7), transcription factor (WRKY22), serine/threonine-protein kinase (D6PKL1), and serine/threonine receptor kinase (NFP) genes were induced, as positive regulators in defence mechanisms against powdery mildew. Polygalacturonase Inhibitor (PGIP) did not express after P. xanthii inoculation of Camlica, resulting in susceptibility. After inoculation, callose synthase (CALLOSE) and cinnamyl alcohol dehydrogenase (CAD) gene expression levels were increased in resistant Meltem, but Hypersensitive Reaction (HR) and ROS formation were only linked in the tolerant VT18. Powdery mildew development was less in Meltem than in VT18, indicating that cell wall thickening and HR play separate roles in resistance to this disease.
Review Literatur : Kualitas Hidup Penyandang Diabetes Mellitus Ditinjau Dari Health Locus Of Control
Authors: Ramadhani Milenia , Induniasih Induniasih , Sutejo Sutejo
Published: May 2022

Health Locus of Control (HLoC) is an important indicator in self-care that plays a role in improving the quality of life for people with Diabetes Mellitus (DM). It is known that the quality of life of people with diabetes is affected by HLoC. This study uses a literature review method using the article databases PubMed, Science Direct, Proquest, Google Scholar, Cohcrane Library, Sage Publications, Researchgate, and EBSCOhost. Providing a good and correct understanding of perceptions, attitudes and behavior in people with DM can improve HLoC and their quality of life. It is proven that HloC has a positive and significant effect on the quality of life of people with DM.
Tinjauan Lama Waktu Pendistribusian Rekam Medis Rawat Jalan di Rumah Sakit Umum Bhakti Asih
Authors: Pratiwi Adinda , Widjaja Lily , Muniroh Muniroh , Putra Daniel Happy
Published: May 2022

Medical record is written or recorded information regarding identity, history taking, physical determination, laboratory, diagnosis of all medical services and actions provided to patients and treatment, whether inpatient, outpatient or receiving emergency services. Distribution in the health sector, especially medical records, has the meaning of a process of distributing medical records to each polyclinic addressed by the patient according to the medical record number. Minimum Service Standards (SPM) are provisions regarding the type and quality of basic services in the speed of providing medical records, the standard time for providing medical records for outpatient services is 10 minutes. This research was conducted at Bhakti Asih Hospital located at Jalan Raden Saleh No. 10, Karang Tengah, Tangerang City, Banten 15157. The purpose of this study was to determine the length of time for the distribution of outpatient medical records at Bhakti Asih General Hospital. This type of research uses descriptive quantitative methods. Data collection techniques used are observation and interviews. In this study, the population was all outpatient medical records in the period June 2021 with a sample of 96 outpatient medical records, using the Incidental/Convenience sampling technique. The results of this study can be seen that 52 medical records (54.16%) have met the SOP 10 minutes, while 44 medical records (45.83%) have not met the SOP 10 minutes. The time of calculating the distribution of outpatient medical records with 96 samples for 10 days with a total time of 984 minutes obtained an average time of distribution of outpatient medical records of 10.25 minutes.
Analisis Ketepatan Kode Diagnosis Typhoid Fever Pada Rekam Medis Rawat Inap di Rumah Sakit Islam Karawang Tahun 2020
Authors: Nurfena Deta Nurfena , Indawati Laela , Dewi Deasy Rosmala , Fannya Puteri
Published: May 2022

Medical record is a file containing records and documents regarding patient identity, examination, treatment, actions and other services that have been provided to patients. where one of the services provided is the management of patient medical record documents that contain coding of diagnoses and actions given to patients. The implementation of coding disease diagnoses in hospitals is a very important activity, namely by classifying disease diagnoses into several groups for the benefit of reports that the hospital does every month, both for internal reports and external reports and plays an important role in the financing system at the hospital itself. The purpose of this study was to determine the accuracy of the diagnosis code for typhoid fever in inpatients at the Karawang Islamic Hospital. The research methodology was carried out using quantitative descriptive methods, the population was 200 medical records of typhoid fever patients in 2020, with a total sample of 67 samples. The sampling technique used is simple random sampling. How to collect data is done by direct observation. The accuracy of the code obtained is 31 (46%) correct codes and 36 (54%) incorrect codes, the inaccuracy of the code is caused by the medical record professional staff in charge of the coding section who are still not focused and not careful with laboratory results to determine the results of the coding. It is correct and only codes for the H titer, while in determining the diagnosis of typhoid fever, it is seen from the O titer. Suggestions for coding the diagnosis carried out at the Karawang Islamic Hospital are expected that the coding is carried out correctly according to the diagnosis, history, and laboratory results.
Evaluasi Penerapan Sistem Informasi Manajemen Puskesmas (SIMPUS)
Authors: Aldio Ahmad Hikmi , Dewi Deasy Rosmala , Yulia Noor , Viatiningsih Wiwik
Published: May 2022

In evaluating the implementation of the Puskesmas Management Information System (SIMPUS) at the puskesmas, it is expected to be able to minimize the accumulation of patients the health service procedures at the puskesmas and also to foster more enthusiasm for the officers at the puskesmas so that services become more effective. So it is necessary to evaluate the implementation of the health center management information system (SIMPUS). Objective: evaluate the implementation of the puskesmas management information system (SIMPUS) to find out what methods are used in evaluating the implementation of the puskesmas management information system (SIMPUS). This study uses the google scholar database in computing a literature review search by using the keyword search for this research journal, namely ” Evaluation of applications (SIMPUS) at the puskesmas. Research results in it can be seen that the most dominant SIMPUS evaluation used is Hot-fit while the least is the cloud-based methods in evaluating the implementation of the puskesmas management information system (SIMPUS). The puskesmas management evaluation information system (SIMPUS) has several methods in implementing the SIMPUS evaluation, namely, web-based, hot-fit, and cloud-based.
Tinjauan Kelengkapan Pengisian Formulir Assesment Awal Poli Klinik Pasien Rawat Jalan Menggunakan Metode IAR
Authors: Safitri Dinda Melani , Fannya Puteri , Indawati Laela , Rosmala Dewi Deasy
Published: May 2022

The hospital is one of the health care facilities with various services helping people who have health probems. Medical record is a file that contains records and data related to patient identity, examination results, treatment history that has been given, other actions and services that have been carried out to patients. This study aimed to describe the completeness of filling the initial polyclinic assessment form. The methode of this study was descriptive analysis. The population of this study were the initial assessment of the physiotherapy clinic 312 medical records, surgery poly 177 medical records, and internal medicine clinic 457 medical records. And the sample of this research is 91 medical records. The results showed that from 91 medical records, 70 (77%) of forms is complete and 21 (23%) of forms is incomplete, which consisted of complete patient identification 80 (88%) and incomplete 11 (12%), completeness of important reports/notes 54 (59%) and incomplete 37 (41%), completeness of author authentication 73 (80%) and incomplete 18 (20%), and completeness of good records 72 (79%) and incomplete 19 ( 21%).
Tinjauan Tata Ruang Unit Rekam Medis dalam Menjaga Keamanan dan Kerahasiaan Rekam Medis di RSUD Kembangan
Authors: Tri Putra Iqbal , Fannya Puteri , Widjaya Lily , Muniroh Muniroh
Published: May 2022

In the Medical Record Unit of the Kembangan Regional General Hospital, the work space of the medical record unit is directly related to the active medical record storage room, the door of the medical record unit at the Kembangan Regional General Hospital does not yet have a secret key or additional security such as a fingerprint. The purpose of this study was to determine the layout of the medical record unit in maintaining the security and confidentiality of medical records at the Kembangan Regional General Hospital. This study used quantitative descriptive methods with observation and interview data collection techniques, as well as direct measurements in the workspace and storage of the medical record unit of the Kembangan Regional General Hospital using a measuring instrument in the form of a building meter, then to determine the need for storage space obtained from the calculation of shelf requirements. medical record storage using the formula according to the International Federation of Health Information Management Associations. The results of the research are in the medical record unit of the Kembangan Regional General Hospital already have standard operating procedures related to the security and confidentiality of medical records but in practice it has not been implemented optimally. Inadequate facilities and infrastructure can be seen from the current work area of 10.27 m3, it should takes 15 m3, the storage space is still minimally lit and does not meet the standards. Suggestion: it is better if standard operating procedures have not been implemented to be implemented immediately.
Tinjauan Prosedur Pendaftaran Pasien Rawat Inap di RSU Bhakti Asih Tangerang
Authors: Fandhika Lilin Tata , Fannya Puteri , Rumana Nanda Aula , Yulia Noor
Published: May 2022

The inpatient registration procedure contains a collection of patient data that is admitted per day, from the existing data registered for inpatient registration, it can be seen the number of patients admitted per day, the number of patients admitted per treatment room. The purpose of this study was to determine the procedure for registering inpatients at Bhakti Asih General Hospital, Tangerang. This type of research uses a qualitative descriptive method. Data collection techniques used are observation and interviews. The results of this study are related to the implementation of inpatient registration procedures, there are obstacles regarding incomplete requirements at the time of registration such as personal identity cards (KTP/KK), patient referral letters and the lack of registration officers so that there is a buildup during inpatient registration. the lack of completeness in the patient identity requirements as a condition for patient registration, therefore the officer must educate the patient to make a statement letter for files that are left behind 2 X 24 hours or before the patient goes home. to be brought as terms and procedures of patient registration at the hospital.
Faktor Risiko Pasien Acute Limb Ischemia
Authors: Admadiani Fhahira Rizkhika , Ekoputranto J Nugroho , Soebroto Heroe , Subagjo Agus
Published: May 2022

Acute Limb Ischemia (ALI) is a classification of peripheral arterial disease that causes decreased blood flow to the extremities, with onset within 2 weeks and characterized by 6 'P's, namely pallor, pain, perishing cold, pulseless, paralysis, and paresthesia. This can be identified through several risk factors, including: diabetes, smoking, gender, high blood pressure, age,hyperlipidemia, atrial fibrillation (AF) and diabetes. This study aims to identify risk factors in ALI patients. Hospital identification. Soetomo Surabaya Period January 2016 – March 2019. This study uses a total sampling technique. This study uses a descriptive cross sectional method with medical record instruments and direct interviews with patients. Twenty-five (25) patients were known to have ALI (14 males and 11 females), and the age of the patients ranged from 65 to 69 years (20%). The causes of risk included a history of smoking obtained from 10 subjects (40%), a history of hypertension in 7 subjects (28%), a history of stage 1 hypertension, a history of diabetes mellitus with the highest blood glucose test value > 126 mg/dl up to 10 people. . (62.5%), with a history of hyperlipidemia, with total cholesterol within normal limits of up to 4 (66.7%), LDL in the normal range of not more than 3 (60%), and HDL with 2 with low HDL values (40%). ), and the highest triglyceride levels were within the normal range. Electrocardiographic examination revealed 7 patients (28%) with atrial fibrillation. Most of the ALI patients in this study were aged between 65 and 69 years and were male. Most ALI patients in this study were 65-69 years old and males. The most common risk factors for ALI patients were hypertension, diabetes mellitus, and hypercholesterolemia.
Pengaruh Mobilisasi Dini terhadap Berkemih Spontan Pasca Bedah Sesar dengan Anestesi Spinal di Rumah Sakit TK. IV IM 07.01 Lhokseumawe
Authors: Nur Afifah , Millizia Anna , Iqbal Teuku Yudhi
Published: May 2022

Cesarean section requires anesthetic efforts to relieve pain in the patient. The type of anesthesia commonly used is spinal anesthesia. Urinary retention is one of the side effect on using spinal anesthetic drugs caused by blockade of spinal cord conduction as high as the S2-S4 segment which innervates the urinary bladder which can lead to UTI. One of the actions that can accelerate spontaneous voiding is early mobilization step by step after cesarean section. This study aims to determine the effect of early mobilization on spontaneous voiding after cesarean section with spinal anesthesia at Level IV IM 07.01 Hospital Lhokseumawe. Method that used in this research is quasi-experimental design with  one-group posttest-only design, a population of 53 mothers after cesarean section with spinal anesthesia at Level IV IM 07.01 Hospital Lhokseumawe in October - November 2021. Data analysis used univariate and bivariate with Fisher Exact Test with 95% confidence level, = 5%. The result showed there was an effect of early mobilization on spontaneous voiding after cesarean section with spinal anesthesia at Level IV IM 07.01 Hospital Lhokseumawe with p value = 0.037 and OR = 6.346 (95% CI = 1.091-36.921). The conclusion of the study that there is an effect of early mobilization on spontaneous voiding after cesarean section with spinal anesthesia at Level IV IM 07.01 Hospital Lhokseumawe in 2021 and early mobilization had an effect 6 times on the initial time of voiding.
Perbedaan Kuantitas Lakrimal Sebelum dan Sesudah menggunakan Komputer pada Pekerja PT. Bank Syariah Indonesia Kota Lhokseumawe menggunakan Uji Schirmer I
Authors: Madina Aqsha , Maulina Nora , Sayuti Muhammad
Published: May 2022

The use of computers continues to increase over time and has become a daily necessity. In line with this, dry eye complaints often arise from workers who use computers. The decrease in the production of tear secretion is closely related to the use of computers for a long time, where the longer the duration of use, the lower the frequency of blinking which results in an increase in tear evaporation, so the eyes will become dry and uncomfortable. This study intends to see the difference in lacrimal quantity before and after using the computer at PT. Indonesian Islamic Bank in Lhokseumawe City. The method used in this study is a quasi-experimental (quasi-experimental) research design in the form of a pretest-posttest control one group design and uses primary data taken through the examination of the Schirmer I test to 31 respondents. The results showed that 22 respondents (71%) had decreased tear secretion, 2 respondents (6.5%) had increased secretions, and 7 respondents (22.6%) had constant secretions. Statistical analysis using the Wilcoxon alternative test with the results obtained a significant value of 0.002 (p<0.05), so statistically there is a statistically significant difference in the mean of tear secretion with the Schirmer I test in PT. Indonesian Islamic Bank in Lhokseumawe City. The conclusion of this study is that there are differences in the quantity of lacrimal before and after using the computer at PT. Bank Syariah Indonesia in Lhokseumawe City uses the Schirmer I . test.
Deteksi Tingkat Cemaran Bakteri Staphylococcus Aureus pada Daging Ayam Broiler yang Dijual di Pasar Tradisional Kota Lhokseumawe
Authors: Amirah Amirah , Sahputri Juwita , Zubir Zubir , Khairunnisa Cut
Published: May 2022

Chicken meat is a product from poultry farming which is very important for meeting food needs. Foods that are often the cause of S. aureus poisoning include meat, meat products, and poultry. This study aims to determine the quality of broiler meat as seen from the contamination and level of S. aureus bacteria contamination. The research design is a descriptive laboratory test, using the Total Plate Count (TPC) method listed in SNI 2897:2008, carried out at the Fundamental Science Lab. The research sample was broiler chicken as many as 11 samples from RPA in the traditional market of Lhokseumawe city. The examination started with culturing in BPA media, followed by qualitative tests (identification) including Gram staining, coagulase test, and quantitative test (TPC), namely counting S. aureus colonies on BPA media. The results showed that from 11 samples, no growth characteristics of S. aureus were found. The conclusion is that the broiler meat from the Chicken Slaughterhouse (RPA) located in the traditional market of Lhokseumawe city which was tested met the requirements set by SNI regarding S. aureus bacterial contamination.