bluuebunny/crossref_metadata_2025 huggingface dataset:
Insights into Automated Attractiveness Evaluation from 2D Facial Images: A Comprehensive Review
Authors: Ibrahem Ali , Saeed Jwan , Abdulazeez Adnan
Published: December 2024

Predicting facial beauty in computer vision is a relatively emerging research area with diverse applications. However, Facial Beauty Prediction (FBP) has various challenging possibilities due to the lack of a universally accepted assessment procedure for facial beauty, the scarcity of sufficient available databases and computational models, and the way of extracting discriminative features to quantify facial attractiveness. This paper comprehensively reviews the 2D facial image beauty analysis and prediction research that utilizes computation, machine, and deep learning techniques. It introduces the limitations and makes a critical analysis of this research area. Beauty hypotheses, feature extraction, evaluation methods, and FBP benchmark datasets that can help measure the effectiveness of the automatic attractiveness assessment approaches are discussed and analyzed. In addition, this paper tries to figure out the answer to the most debatable question that says, “which face organs contribute to facial beauty and to what extent?”. It also highlights concerns and challenges in the FBP domain that can provide a foundation for future work and further development in automatic facial beauty estimation and evaluation
Left Ventricular Reverse Remodeling After Successful Living Donor Kidney Transplantation
Authors: Hidaka Sumi , Kobayashi Shuzo , Tanabe Kazunari ,   the VINTAGE Investigators
Published: December 2024

Background:

The impact of kidney transplantation (KT) on left ventricular (LV) remodeling remains poorly understood. This study aimed to evaluate the effect of KT on LV reverse remodeling, utilizing echocardiographic LV geometric patterns as a key assessment tool.

Methods:

In 100 recipients who underwent living KT between 2012 and 2022, we evaluated changes in the distribution of LV geometric patterns (normal geometry, concentric remodeling, eccentric hypertrophy, and concentric hypertrophy) between baseline and 1 year post-transplantation. These patterns were categorized based on LV mass index (LVMI) and relative wall thickness (RWT) assessed via echocardiography.

Results:

Overall, LV geometric patterns improved or remained stable in 81% of recipients, with worsening in 19%. The proportion of normal geometry increased from 15% to 19%, and concentric remodeling from 30% to 45%, while eccentric hypertrophy decreased markedly from 20% to 3%. Concentric hypertrophy remained relatively stable at 33% (p=0.036). Subgroup analysis revealed that 47% of those with pre-KT normal geometry progressed to LV remodeling, while 77% with concentric remodeling remained stable. In contrast, 55% with eccentric hypertrophy experienced reverse remodeling, and 49% with concentric hypertrophy also showed reverse remodeling. These subgroup results suggest an interaction between the effect of KT on LV reverse remodeling and the pre-KT LV geometric patterns. Multivariable analysis identified E/e' > 9.5 (OR 2.01, 95% CI 1.10-3.67, p=0.024) and acute antibody-mediated rejection (OR 2.44, 95% CI 1.01-5.87, p=0.047) as independent predictors of LV remodeling progression.

Conclusions:

KT can lead to improvements in even advanced LV geometric patterns, although this effect may be diminished in the presence of pre-KT diastolic dysfunction or the occurrence of acute rejection. Since recipients rarely achieve complete renal recovery, echocardiographic monitoring remains crucial post-KT. Future studies are needed to establish whether these observed improvements in LV reverse remodeling directly translate into long-term reductions in cardiovascular events.
Variación y polisemia del sintagma tan luego
Authors: Di Tullio Ángela L.
Published: December 2024

Tanto el adverbio luego como el sintagma tan luego son expresiones polisémicas: el primero, según contenga o no el rasgo de inmediatez; el segundo, en relación con el carácter composicional o lexicalizado de su formación. Después de una breve introducción dedicada a los significados de luego en el mundo hispanohablante, se analizarán las construcciones que se forman composicionalmente: un sintagma adverbial y una subordinada temporal. En cambio, la locución adverbial rioplatense homónima tan luego se caracteriza por haber perdido el significado temporal y adquirido el de focalizador, similar al que aportan los adverbios precisamente o justamente. Como este resultado no se deriva composicionalmente, su formación se explicará a partir del reanálisis de sus constituyentes. Esta construcción no ha recibido la atención de gramáticos ni de otros lingüistas, por lo que este trabajo pretende ser un aporte para el conocimiento de una locución rioplatense que, aunque poco usada actualmente en la conversación, sigue apareciendo en la lengua escrita, literaria o periodística.
Васкулярная компрессия как причина развития краниальных нейропатий: обзор литературы
Authors: Сидорович Р.Р. , Марьенко И.П. , Родич А.В. , Давидян А.В. , Забродец Г.В. , Клебан А.В.
Published: December 2024

Нейроваскулярные конфликты (синдромы васкулярной компрессии) черепно-мозговых нервов – патология, обусловленная анатомическими особенностями взаимоотношений сосудистых структур и черепно-мозговых нервов, при котором происходит прилегание сосуда к нерву, что приводит к формированию стойкой нейропатии в зоне интереса нервных структур. Частота встречаемости нейроваскулярных конфликтов колеблется от 11 случаев на 100 000 населения при гемифациальном спазме до 0,7 случая на 100 000 населения при невралгии языкоглоточного нерва. Определение анатомических взаимоотношений между стволами черепно-мозговых нервов и сосудистыми структурами задней черепной ямки является важным для диагностики и прогноза функциональных исходов оперативного вмешательства.

Neurovascular conflicts (vascular compression syndromes) of cranial nerves is a pathology determined by anatomical features of interrelations between vascular structures and cranial nerves, in which a vessel adheres to a nerve, resulting in persistent neuropathy in the area of interest of nerve structures. The incidence of neurovascular conflicts among population ranges from 11 cases per 100,000 in hemifacial spasm to 0.7 cases per 100,000 in lingual nerve neuralgia. Determining anatomical interrelations between cranial nerve trunks and vascular structures of the posterior cranial fossa is important for diagnosing and predicting functional outcomes of surgery.
Dimorfismo Sexual Relacionado a Dimensão do Espaço Aerofaringeo: um estudo transversal
Authors: Ferraz Aline Xavier ,  Bonaccorso Bruno Salvatore Carneiro ,  Silveira Arthur Felipe Golin , Freitas Pedro de Jesus , Priolo Filho Sidnei , Stechman-Neto José , Araujo Bianca Marques de Mattos de , Schroder Ângela Graciela Deliga , Araujo Cristiano Miranda de
Published: December 2024

Objetivo - O objetivo deste estudo foi analisar se existe dimorfismo sexual correlacionando à dimensão do espaço aéreo faríngeo entre homens e mulheres Método - Um total de 405 telerradiografias de pacientes (239 mulheres e 166 homens). Os dados foram analisados pelos testes qui-quadrado e teste t de Student, com intervalo de confiança de 95% e adotando p < 0,05 como nível de significância, utilizando o software JASP versão 0.17.2.1. Resultados: Houve diferença significativa para o espaço bucofaríngeo (<0.01) entre homens e mulheres, já o espaço nasofaríngeo não houve diferença (0.097). A média de idade da amostra variou entre 36.0 ±13.2 feminino e 36.4 ±12.1 masculino. Conclusão: Os resultados obtidos neste estudo sugerem que existe presença de dimorfismo sexual quando comparado as medidas dos espaços bucofaríngeo, já em comparação com espaço aéreo nasofaríngeo não existe diferença.
Palavras-chave: Dimorfismo sexual; ciência forense; espaço aerofaringeo;
O Vínculo Terapêutico e suas Implicações na Prática Clínica Fonoaudiológica: uma revisão sistemática
Authors: Paisca Adriele Barbosa , Jampersa Lucas ,  Taveira Karinna Veríssimo Meira , Araújo Cristiano Miranda de , Dias Carlos Eduardo Borges , Massi Giselle Aparecida de Athayde
Published: December 2024

Introdução: o vínculo terapêutico pode ser considerado o ponto central do processo terapêutico fonoaudiológico, pois possibilita a construção de um trabalho significativo entre os participantes da prática clínica. Objetivo: Avaliar as implicações do vínculo terapêutico, no campo da clínica fonoaudiológica. Procedimento metodológico: Combinações de palavras apropriadas e truncamentos foram selecionados e ajustados, especificamente, para cada banco de dados eletrônico. Os estudos foram selecionados por dois revisores independentes e analisados em duas fases. O risco de viés foi avaliado com a ferramenta JBI’s critical appraisal tools Resultados: De 2.229 artigos, 49 foram elegíveis para leitura de texto completo e seis foram incluídos. Considerando o risco geral de viés dos estudos, dois artigos foram julgados com baixo risco de viés, dois com risco moderado e dois com alto risco. Devido à alta heterogeneidade metodológica entre os estudos incluídos e a ausência de dados quantitativos, não foi possível realizar a meta-análise. Pela análise qualitativa, foi possível verificar que o vínculo terapêutico apresenta implicações significativas no processo terapêutico fonoaudiológico, tais como, melhoria das habilidades comunicativas dos pacientes, potencialização de fatores relacionados à motivação e ao engajamento terapêutico. Conclusão: O vínculo terapêutico apresenta influência positiva no fazer clínico, assumindo papel relevante no desenvolvimento do trabalho fonoaudiológico. Palavras-chave: vínculo; fonoaudiologia; clínica; terapia; revisão sistemática
Economic Performance Assessment of Malt Dust Derived Biochar Application for Groundwater Treatment: A Circular Economy Approach
Authors: Yapıcıoğlu Pelin
Published: December 2024

This paper mainly aimed to determine the energy cost reduction for groundwater treatment using the economic and innovative biochar adsorption process. From this point of view, malt dust which is a by-product of brewery industry was utilized as the agro-industrial raw material for the biochar production, in this study. Slow pyrolysis was performed under three different temperatures which are 250 (M1), 300 (M2) and 500 ºC (M3) to produce the biochar. This unique biochar was used for the groundwater treatment as an innovative and effective water treatment technique. The groundwater was sampled from three observation points which were Uğraklı, Yaygılı and Bolatlar resources located at the Harran Plain before and post-irrigation. An economic performance assessment was carried out to benchmark the conventional and biochar adsorption processes. A new energy cost indicator (ECI) was developed based on nitrate (NO3-) removal. Averagely 91.69% of removal efficiency of NO3- was reported using three types of malt dust derived biochar. Approximately, 65.87% of reduction on energy costs was obtained using biochar adsorption process.
Spatiotemporal Analysis and Machine Learning-Based Prediction of Air Quality in Indian Urban
Authors: Singh Sitesh Kumar , Jain Rituraj , Palaniappan Damodharan , Parmar Kumar , T Premavathi , Gothania Jaishri
Published: December 2024

Air pollution, more specifically Particulate Matter (PM2.5 - particulate matter with diameter less than 2.5 micrometers), threatens the public health most critically in urban Indian cities, and Delhi, among them, presents the most acute challenge. This study predicts the concentrations of PM2.5 using machine learning models using data ranging from 2010 to 2023 and assessing model fit via R², RMSE, MAE, and MAPE metrics. Models tested: Random Forest, Gradient Boosting, AdaBoost, Histogram-Based Gradient Boosting, XGBoost. The Random Forest model is extremely effective for the training set (R² = 0.99) but shows the highest degree of overfitting, with R² of 0.35 for the test set. Gradient Boosting has a more balanced result, with R² 0.54 and 0.48, respectively on the training and test set, as well as fewer errors (RMSE: 56.46, MAE: 39.60, MAPE: 0.50). Hence, it is a good predictor. AdaBoost performs the worst with an R² of 0.28 on the test set and the highest errors in terms of RMSE: 66.86, MAE: 52.34, MAPE: 0.94. Histogram Gradient Boosting and XGBoost: both models yield an average accuracy value, but the Gradient Boosting model is still a tad better than the former ones in terms of RMSE and MAE. Thus, Gradient Boosting happens to be the most accurate model considering generalization as well as accuracy for the prediction of the concentration of PM2.5. These results will be highly beneficial to policymakers to adopt machine learning-based air quality forecasting for better environmental management and the protection of public health.
The Incompleteness of Central Planning
Authors: Nguyen Hai-Trieu v.
Published: December 2024

This article aims to flesh out the implication of Kurt Gödel’s incompleteness theorems for the computability of social economic planning. Specifically, the article challenges the claim of modern technosocialists that access to large sets of economic data allows the social planner (or, equivalently, a supercomputing machine) to solve the planning problem for the economy. The article extends the computability problem proposed by the literature on computable economics for market socialism to the case of technosocialism. The conclusion is that even if all the practical challenges could be overcome, social economic calculation and planning are still impossible from a computation-theoretic point of view.
Eryptosis contributes to gestational diabetes mellitus in maternal obesity
Authors: Lazurenko V.V. , Zhelezniakov O.Yu. , Prokopiuk V.Yu.
Published: December 2024

Background. Obesity is considered to be a risk factor for Gestational Diabetes Mellitus (GDM), which is characterised by hyperglycaemia in pregnant women. Recent studies have demonstrated that glycated erythrocytes are more prone to eryptosis, a unique regulated cell death observed only in mature erythrocytes.

The aim of the current study was to analyse how eryptosis might contribute to GSM in maternal obesity.

Materials & Methods. Eryptosis parameters were assessed in pregnant women enrolled for the study: group 1 consisted of 12 obese pregnant women without the signs of GDM, 15 pregnant women without obesity but with GDM were included in group 2, 14 obese pregnant women with GDM were in group 3, group 4 (control) consisted of 15 pregnant women without the signs of obstetric and extragenital pathology. Phosphatidylserine externalisation was assessed by flow cytometry following Annexin V-FITC staining of circulating erythrocytes isolated from the pregnant women. Additionally, 2',7'-dichlorodihydrofluorescein diacetate (H2DCFDA) staining was used to analyse oxidative stress parameters in circulating erythrocytes.

Results. Groups 1, 2 and 3 of pregnant women showed a higher degree of ROS-dependent eryptosis compared to the control group (IV). There was no statistically significant difference (p>0.05) in the eryptosis of circulating erythrocytes between pregnant women of groups 1 and 2. However, the percentage of phosphatidylserine-dispersed erythrocytes in eryptosis and the level of ROS was statistically significantly higher in pregnant women of group 3 compared to pregnant women of groups 1 and 2.

Conclusions. GSM associated with maternal obesity is accompanied by accelerated ROS-dependent eryptosis. Enhanced eryptosis might act as an additional factor contributing to thrombosis and endothelial dysfunction in obese pregnant women with GDM.

Keywords: pregnancy, phosphatidylserine, flow cytometry, Annexin, erythrocytes.
Implementation of a mobile application for the dissemination of tourism in México
Authors: Sánchez-Juárez Ivan Rafael , Paredes-Xochihua Maria Petra , Martínez-Pérez José Randall
Published: December 2024

The arrival of international tourists to Mexico increased by 10% in 2023 compared to 2022, with an arrival of 42 million 153 thousand visitors in 2023 and 38 million 325 thousand in 2022, a difference of 3 million 828 thousand visitors; This reflects the growth in the tourism sector and contributing to the country's economy. The article presented below contains the implementation of a mobile application that allows the dissemination of tourist places in Mexico. The mobile application, developed for the Android operating system, has different types of users, including the owner or manager of the place and the tourist; The owner can record the information of the place such as the address, hours, services and events among others. The tourist will be able to see this information and leave comments of each place, allowing the tourist to have a better organization of the trip itinerary
Know-how as element of strategic management in an it solution company
Authors: Varela-Couoh Andrea , Quijano-García Román , Guillermo-Chuc Giselle , Alcocer-Martínez Fidel
Published: December 2024

The health crisis known as COVID-19 had consequences in the personal and business environment where human beings interact and it proved, among other aspects, that organizations with established administrative documents and previous strategic planning were able to face the negative economic effects and even innovate to remain active in the economic sectors where they operate. To identify the processes developed with exclusive knowledge of the work team members aimed to increase productivity within their organization, it was developed a case method study about a MSME from the IT services field that has remained active due to the knowledge acquired and transmitted without formal management of it, the results of the intervention allow to establish the opportunity to implement the know-how of the entity to strengthen the commitment of the bond organization collaborators and create a competitive advantage aimed to its growth based on strategic planning.
ESTUDO DE CASO DE VIABILIDADE FINANCEIRA E ARQUITETÔNICA PARA CONSTRUÇÃO DE HABITAÇÃO MULTIFAMILIAR A SER COMERCIALIZADA
Authors: Flávia Cartaxo Pessoa Estrêla Stephanni , Ferreira da Costa André , Valentim Afonso Filipe , Karla Garcia Silva Yanna
Published: December 2024

O presente estudo aborda a viabilidade financeira e arquitetônica para a construção de uma habitação multifamiliar na cidade de Cajazeiras-PB. A pesquisa foi conduzida com abordagem qualitativa, utilizando levantamento bibliográfico, estudo de caso e simulação de financiamento. Foram realizadas análises urbanísticas e financeiras do terreno, aplicação de parâmetros legais e cálculos baseados no Custo Unitário Básico (CUB). Os resultados indicam que o terreno é adequado para um projeto de oito pavimentos, com otimização do custo e espaço. O investimento total estimado, incluindo terreno e construção, é de R$ 7.267.154,26, com custo médio de R$ 236.182,50 por unidade habitacional, a viabilidade financeira foi confirmada, especialmente para investidores interessados em venda ou locação. Embora o público-alvo local seja limitado pela renda necessária para aquisição, o mercado de aluguel em Cajazeiras mostra grande potencial, impulsionado pela demanda de estudantes e profissionais das instituições de ensino locais. Por fim, conclui-se que projeto é viável e pode gerar lucros, especialmente com foco na locação, destacando a importância de estudos semelhantes para apoiar decisões de investimento e a necessidade de um planejamento cuidadoso para alcançar bons resultados. Ademais, a pesquisa é uma importante experimentação e aproximação no que se refere ao mercado imobiliário através da prática voltada para as atividades profissionais (estudo de viabilidade), que é um competência do arquiteto. A continuidade dessa temática é crucial para promover soluções habitacionais adaptáveis e garantir um desenvolvimento urbano sustentável, atendendo tanto às necessidades sociais quanto ao mercado imobiliário local. Assim, o estudo oferece um importante panorama para o setor da construção civil, com implicações diretas para a gestão de projetos e investimentos imobiliários.

Palavras-chave: Viabilidade financeira; Habitação multifamiliar; Construção civil; Investimento imobiliário.
Pharmacokinetics and Pharmacodynamics: An Ayurvedic Perspective
Authors: Madgulwar Dr.Yogesh D , Kalpana Bhaishajya , J.Shewalkar Dr.Kalyani , Kalpana Bhaishajya
Published: December 2024

Introduction:Ayurveda is an ancient system of
medicine that originated in India more than 3,000
years ago. It focuses on maintaining balance in the
body, mind, and spirit, primarily through the use of
diet, herbal remedies, lifestyle practices, and
treatments like massages and detoxification
procedures. The central principle of Ayurveda is
that health is achieved when the body's three
doshas—Vata, Pitta, and Kapha—are in
balance[1]. Each dosha is made up of the five basic
elements of nature: earth, water, fire, air, and ether
(space). Ayurvedic medicine works by addressing
the root cause of illness and restoring balance in the
body. Its effects are multi-dimensional, targeting
physical, mental, and spiritual aspects of
health.Materials and Methods: The present study
evaluates the therapeutic action of Ayurvedic
medicines which can be administered alone or in
combination.The pharmacological action of
Ayurvedic drugs and preparations can be explained
on the basis of Panchamahabhuta and Tridosha
theories.
Result and Discussion: The drug's action in the
body depends on Rasadi Panchaka, including Rasa,
Guna Virya, and Vipaka Prabhava [2]. These
elements, along with Prabhava, influence the
Sareera based on Dosha Prasamana, Dathu
Pradooshana, and Swasthahitha. Prabhava, a
hypothesis, justifies the innate action of a medicine,
independent of the other four
components.Conclusion: Ayurvedic medicine's
pharmacology is explained using Panchamahabhuta
and Rasadhi Panchaka principles, which
superimpose Samanya and Vishesha Karma. The
pharmacokinetics of Ayurvedic drugs is still
evolving, bridging traditional medicine with
modern scientific principles. Despite its emphasis
on natural remedies, the PK of these drugs remains
less studied compared to allopathic drugs.
Musa Balbisiana: Unravelling Its Pharmacological Properties and Health Benefits
Authors: Sadab Sadab , Singh Prof. (Dr.) Aaditya , Sharma Dr. Rahul
Published: December 2024

Musa balbisiana, a wild banana species native to
Asia, is a member of the Musaceae family. Despite
its numerous medicinal properties, including the
use of its seeds, pulp, inflorescence, and stem, the
banana peel is often overlooked for medicinal
purposes. Standing over 6 meters tall with a 30 cm
diameter base, Musa balbisiana displays distinctive
features such as large leaves and solid stems,
making it an interesting plant for botanical studies.
This study explores the therapeutic capabilities of
the banana peel, revealing its potential
pharmacological benefits. Chemical analysis of the
Musa balbisiana plant revealed a wide variety of
active compounds, highlighting its potential for
medicinal use. Lab studies showed that the plant
has significant anti-inflammatory properties,
reducing inflammation-causing chemicals. The
flowers have reddish to brownish hues. Many parts
of the plant contain high levels of specific
compounds, including terpenoids, alkaloids,
saponins, flavonoids, and tannins. These
compounds contribute to the plant's antiinflammatory, antibacterial, cholesterol-lowering,
and antifungal properties. Dried fruits contain a
potent blend of vitamins, minerals, and elements
that support tissue growth and provide energy.
They are particularly rich in calcium, chloride,
carbonate, and potassium. Research indicates that
dried fruit supplements may protect against heart
disease by reducing inflammation and oxidative
stress. Traditionally, extracts from M. balbisiana
have been used as contraceptives. Additionally, the
fruit's peel exhibits hepatoprotective properties,
while its root has shown anti-diabetic activity.
Geographically, this plant is found in Southeast
Asian countries such as India, Sri Lanka, Malaysia,
China, Myanmar, Thailand, Nepal and Indonesia.
Organometallic Compounds
Authors: Kounda Aryash , Happy Happy , Kumar Verma Dr.Kapil
Published: December 2024

Organometallic compounds have garnered
significant attention in the field of medicinal
chemistry due to their unique properties and
diverse applications in treating various diseases.
These compounds, characterized by the presence of
metal-carbon bonds, exhibit a wide range of
biological activities that make them valuable in
therapeutic contexts. This abstract explores the
introduction of organometallic compounds,
highlighting their benefits, roles in disease
management, design strategies, therapeutic effects,
and mechanisms of action.
The introduction of organometallics into
medicinal applications has opened new avenues for
drug development, particularly in cancer treatment,
antimicrobial therapy, and neurodegenerative
diseases. Their ability to interact with biological
macromolecules allows for targeted drug delivery
and modulation of biological pathways. Benefits of
organometallic compounds include enhanced
potency, reduced side effects, and the potential to
overcome drug resistance.
Organometallic compounds have been
shown to play critical roles in various disease
processes. For instance, platinum-based
compounds, such as cisplatin, are well-established
in oncology, while other metal complexes have
demonstrated efficacy against bacterial infections
and as anti-inflammatory agents. The design of
these compounds often involves optimizing metal
centers and ligands to enhance bioavailability and
selectivity.
The therapeutic effects of organometallics
are linked to their mechanisms of action, which
may include the formation of reactive species,
alteration of enzyme activity, and disruption of
cellular signaling pathways. Understanding these
mechanisms is crucial for the rational design of
new organometallic drugs.
In conclusion, organometallic compounds
represent a promising frontier in drug discovery,
offering innovative solutions to complex health
challenges. Continued research is essential to
unlock their full potential, refine their therapeutic
applications, and enhance our understanding of
their biological interactions.
A Prospective Observational Study Evaluating the Postoperative Pain Experiences Inpatients of General Surgery Department at Tertiary Care Hospital
Authors: Dr V B Vaishnavi, Dr V B Vaishnavi, , A N Thabassum A N Thabassum , Besi Ida J. Pheobe , R. Suriya R. Suriya
Published: December 2024

Background: Postoperative operative pain is a
common condition among postoperative patients. It
is experienced by patients regardless of type of
surgery. Severe pain after surgery is an
unrecognized clinical problem and is associated
with decreased patient satisfaction, delayed
ambulation and an increased risk of cardiac and
pulmonary complications.
Objective: To evaluate the postoperative pain
experiences in patients of general surgery
department at Government Medical College
Hospital during three consecutive postoperative
days.
To evaluate the prescribing practices of analgesics
during the first three consecutive postoperative pain
days.
Result: In this study of postoperative pain
experiences and its management among the patients
who underwent surgical procedures ,number of
males undergoing surgeries was high .65 out of 100
patients (61.90%)were males .Majority of surgical
procedures performed was appendectomy followed
by hernioplasty .
41.9% patients underwent appendectomy and
25.7% patients underwent hernioplasty .More
number were performed in patients between 18-33
years (38%) followed by those between 34-
49years (36%).There was high incidence of mild –
moderate pain (61.9%).Postoperative pain had
significant impact with the activities of daily living
.The mean interference score of doing activities in
bed was 4.17+/-2.09 and 4.57+/-2.09 for doing
activities out of bed and the mean interference
score was 0.5+/-1.91 on sleep. The administration
of analgesic had an association with patient „s
perception of pain.
Conclusion:Postoperative pain had a substantial
impact on patient „s activities of daily living.
Patient centric management of postoperative pain
reduces morbidity and improves patient
satisfaction.
Guduchi (Tinosporacordifolia): A Review Article
Authors: a Surajsingh Subhash Rajput Vd. Rana , Pawar Vd. Parshuram
Published: December 2024

Guduchi of family Menispermaceae. A Sanskrit
word meaning "that which protects body from
diseases" is guduchi. Another name for this herb is
"Amrita," which in Hindu mythology means "the
heavenly elixir." The story says that Guduchi kept
celestial beings young forever by preventing them
from growing old. Because of its many applications
and abundance of life energy, it is considered a
potential drug in Ayurveda. Long before the era of
modern technology, the ancient rishis of the Vedic
era recognised its ability to help prolong life.
Potentially used extensively to treat fever, diabetes,
urogenital tract infections, anaemia, jaundice,
asthma, cardiac disorders, and other conditions, it is
a potential ayurvedic medication. It is a well known
immune-modulator herb used in the correction of
auto immunity. As per Acharya Charak, Guduchi is
one among the four Medya Rasayan where its
Swaras is to bead minis rated to get all the benefits
of rasayan. Its Ras is Tikta, Veerya is Ushna and
Vipakais Madhura. Guna includes Laghu and
Snigdha. It balances Tridoshain the body. Guduchi
is highly rich in anti-oxidants. It also has antipyretic, anti-viral and wound healing
properties.There are many studies already done on
Guduchi and many researches are still going on to
know the effects of Guduchi in the body for the
benefit of the patients.
The Effect of Different Extraction Methods of Sargassum polycystum Pigments on Antioxidant and Anti-Obesity Activities in Vitro
Authors: Susilowati Novy Dwi , Lia Kusmita Lia Kusmita , Sulistyowati Etty
Published: December 2024

The brown algae Sargassum polycystumcontains
the pigment fucoxanthin. Fucoxanthinis a bioactive
compound useful for antioxidants and anti-obesity.
An appropriate extraction method is required to
obtain a high content of bioactive compounds with
potential as antioxidants and anti-obesity
agents.Themethods of maceration and ultrasonic
extraction were used to search for bioactive
compounds. This study aims to determine the effect
of different extraction methods, namely maceration
and ultrasonic, of the pigment Sargassum
polycystum on antioxidant activity IC50 using the
DPPH method and anti-obesity activity with
pancreatic lipase enzyme inhibitors in vitro. This
research was conducted using fresh Sargassum
polycystum samples with two extraction methods,
namely rapid maceration and ultrasonic, each for
20 minutes, using 100% acetone as the solvent. A
TLC test was conducted to identify the fucoxanthin
pigment, obtaining a standard fucoxanthin Rf of
0.69, and a Rf of 0.69 for both the maceration and
ultrasonic extracts. The phytochemical screening
showed positive results for saponin and steroid
compounds. Antioxidant activity test IC50 DPPH
method and obesity activity with pancreatic lipase
enzyme in vitro, obtained yield percentage results
from the rapid maceration method for 20 minutes
of 1.20 ± 0.09, with antioxidant activity IC50
111.24 ± 0.17 µg/mL and lipase inhibition
percentage 79.23 ± 1.99, yield percentage from the
ultrasonic method for 20 minutes of 1.30 ± 0.11
with antioxidant activity IC50 79.65 ± 0.42 µg/mL
and lipase inhibition percentage 92.35 ± 4.02. The
best results for the effect of yield on antioxidant
activity IC50 and lipase inhibition percentage are
from the ultrasonic extraction method.
Review Article on Khadiradi Vati and Its Effectiveness in MukhaPaka
Authors: Deshmukh Vd. Dhanashree , Chondikar Vd. Shailaja
Published: December 2024

Mukhapaka is the disease that
spreads throughout the mouth. It is the
inflammation of mucous membrane of lips, tongue,
and cheek. It is common problems faced by all
persons. Though, it may seem like a minor problem
but it inhibits the daily activities. Ayurveda has
described four types of Mukhapaka: Vataja, Pittaja,
Kaphajaand Raktaja. Different types of Mukhapaka
have different types of symptoms. Pain relievers,
mouth washes, lotions, corticosteroids, Vit. B12 are
used to treat stomatitis. In present era, world is
looking at Ayurveda for its valuable contribution in
the treatment of any ailment. Sarvasara
Mukharogas are named as Mukhapaka, as they
diffusely spread in the Mukha. Khadiradi Vati is a
traditional Ayurvedic formulation known for its
efficacy in treating oral health issues, particularly
Mukha Paka. This review aims to delve into the
composition, pharmacological properties, and
clinical effectiveness of Khadiradi Vati. By
exploring its mechanisms of action, safety profile,
and holistic benefits.
Design and Simulation of an Optimized Anti-Surge Adaptive Control System for Centrifugal Compressors in Gas Facilities
Authors: Eludu D.O Eludu D.O , Ezeofor C.J Ezeofor C.J , Asianuba I.B Asianuba I.B
Published: December 2024

This research enhances an adaptive control system
for centrifugal compressors using MATLAB
Simulink software, concentrating on gas facilities
such as refineries and natural gas processing plants.
Centrifugal compressors, crucial for these
processes, are susceptible to surges induced by
variable gas demands and operational disruptions,
which, if not managed properly, might lead to
compressor damage. An improved anti-surge
adaptive control system was developed and
simulated, using sophisticated optimization
methods and adaptive control algorithms to
monitor operational circumstances, predict surge
occurrences, and implement preventative actions.
Simulation results demonstrated that the proposed
control system effectively mitigates surge
occurrences, ensuring stable compressor operations
across diverse conditions, while exhibiting
substantial enhancements in the response time of
the anti-surge valve, as well as improvements in
gas compression processes, safety, reliability, and
efficiency. The study advocates for more
investigation into sophisticated control
methodologies, such as the incorporation of
machine learning and model predictive control, to
improve flexible functionalities.
An Overview of Aetiology, Types, Pathophysiology and Treatment of Vitiligo
Authors: Kumari Poonam , Devi Monika , Verma Dr. Kapil Kumar
Published: December 2024

Vitiligo is a chronic skin condition characterized by
the loss of melanin, resulting in white patches on
the skin. Its etiology is multifactorial, involving
genetic predisposition, autoimmune responses, and
environmental triggers. The disorder often presents
with asymptomatic depigmented macules and
patches that can appear on any part of the body,
leading to significant psychological impact and
social stigmatization. The pathogenesis of vitiligo
is complex, involving the destruction of
melanocytes—cells responsible for skin
pigmentation. Autoimmune mechanisms, where the
body’s immune system mistakenly attacks its own
cells, play a crucial role. Genetic factors may also
contribute to susceptibility, while stress, sunburn,
and certain chemicals can exacerbate the condition.
Treatment options for vitiligo aim to restore skin
color or achieve an even skin tone. Therapies
include topical corticosteroids, calcineurin
inhibitors, and phototherapy, which stimulate
regimentation. In more severe cases,
depigmentation of unaffected skin may be
considered for cosmetic uniformity. Psychosocial
support is essential, as vitiligo can significantly
affect quality of life. Ongoing research continues to
explore more effective therapies and a deeper
understanding of the underlying mechanisms of this
complex condition.
An Overview of Trachyspermum ammi (L.): A Comprehensive Review
Authors: Anuraj Anuraj , Shandilya Satya , Kumar Anand , Kumari Dr. Dharmshila
Published: December 2024

Trachyspermum ammi (L.),
commonly known as Ajwain, is a herbaceous plant
in the Apiaceae family. It is prevalent across
regions such as Egypt, Iran, Pakistan, Afghanistan,
India, and parts of Europe. Ajwain seeds, which are
rich in several chemical constituents, are reported
to have a wide range of biological and
pharmacological properties. These seeds exhibit
antiseptic, anaesthetic, antiviral, antimicrobial,
carminative, diuretic, stimulant, nematocidal,
antiulcer, antihypertensive and antitussive
properties. Additionally, these seeds also exhibit
bronchodilator, antiplatelet, hepatoprotective, and
antihyperlipidemic effects. A number of these
properties were noted by early Persian physicians.
Considering the aforementioned pharmacological
attributes, Ajwain seeds hold promise for potential
application in clinical practice. The current study
aims to comprehensively compile information
regarding the chemical composition and biological
activities of Ajwain.
Clinical Application of Vimana Sthana in the Present Era
Authors: Bidgar Vd. Shwetambari , Dande Vd. Bhavana
Published: December 2024

Traditional medicine, such as Ayurveda, Siddha,
Unani, and Yoga, has played an increasingly
important part in India's health system in recent
decades. The primary goal of Ayurveda is to
maintain the health of the healthy individual while
also treating diseases. This treatment-related notion
and its fundamentals were written in a step-by-step
way and grouped into distinct Sthanas. This article
discusses Charaka's archaic vision and the clinical
uses of the notions found in the Vimana Sthana of
Charaka Samhita. Aims and Objectives: To
explore the concepts clinical application of Vimana
Sthana in the present era. Material and Methods:
The available Samhita mainly Charaka Samhita,
with Sanskrit and Hindi commentaries on Vimana
Sthana along with the available commentaries.
Discussion: According to Acharya Charaka,
Vimana Sthana is explained after Nidana Sthana, in
which all etiological elements are thoroughly
explained; yet, if a physician does not understand
the measurement and special properties of Doshas,
he will be unable to treat the patient appropriately.
This Sthana contains eight chapters covering a
wide range of topics that a clinician should be
familiar with before commencing practice. The
therapeutic applicability of each chapter is
examined. Conclusion: Approach to diseases
concept by Acharya Charaka in Vimana Sthana is
progressive, scientific and applied in clinical
application of today’s era also.
Effect of Selenium in Teratospermia and Oligospermia
Authors: Dr. Lokesh. K Dr. Lokesh. K , Purushothaman Dr. Borus , Agwina Xavier Dr. Yashmi , Veerammal Veerammal , Sharma Dr. Suman
Published: December 2024

Selenium, a trace element known for its antioxidant
properties, plays a crucial role in male reproductive
health, particularly in sperm quality. This study
examines the impact of selenium supplementation
on two common male fertility issues:
teratospermia, characterized by abnormal sperm
morphology, and oligospermia, defined by low
sperm concentration. Selenium's antioxidative
properties help mitigate oxidative stress, a
significant factor contributing to sperm
dysfunction. Furthermore, selenium is involved in
modulating testosterone levels, which is crucial for
spermatogenesis. Research indicates that selenium
can enhance sperm motility, viability, and overall
morphology, thereby improving fertility outcomes
in men with teratospermia and oligospermia.
A Review on Importance and Concept of Nityasevaniya Dravyas in Modern Era
Authors: Dr. Rekha Dr. Rekha , Singh Chahar Dr.Devendra
Published: December 2024

Ayurveda is the most ancient and well-developed
science describing about a perfect lifestyle which
says human body system and diseases both origin
from Ahara (Diet). Acharyas have mentioned three
Basic elements i.e. Ahara, Nidra, Brahmacharya by
support of which Ayu can be maintained. At the
same time, society is suffering from the adverse
effects of its excessive use in the form of lifestyle
disorders such as Hypertension, Stroke, Renal
impairments etc. Ahara stands at first place
amongst these three for Healthy Body and Mind.
Acharya Charaka has described few Ahara Dravyas
which should be used regularly are known as
Nityasevaniya Dravyas. Ayurveda has a holistic
and person centric approach towards health
&disease which in turn necessitates consideration
of several factors. The concept of Nityasevaniya
Dravyas offers a valuable approach to healthcare
that is relevant in the modern era. Developing and
validating as enumerated in Ayurvedic classical
texts can help in combating various lifestyle
disorders.
Solanine Toxicity in a Man Following Consumption of Devil’s Fig-A Case Report
Authors: Kakumani Praveen , Wagangeri Ashwini
Published: December 2024

Native to tropical Africa, Solanum
torvum, also known as the Devil’s Fig is a tiny fruit
that grows on a shrub-like plant. The term "turkey
berry" was coined due to its widespread use as a
food source in Turkey. Antioxidants, vitamins, and
minerals like calcium, vitamin C, and plant-based
iron are abundant in these berries. Here is the
example of a 38-year-old man who came to the ER
with turkey berry poisoning after consuming them
several times in the evening and the morning after.
He complained of blurred vision, two quick
episodes of vomiting, and four episodes of loose
stools. The patient had no history of contacting ill
patients or eating stale food. Electrolyte
replenishers and drugs that prevent acetylcholine
buildup were used to treat his symptoms.
Pharmacological and Therapeutic Efficacy of Castor Oil
Authors: Dr. Prajakta Dr. Prajakta , P. Jibhkate P. Jibhkate
Published: December 2024

Background:The most commonly used part of
Ricinus communis is seeds known as Castor Oil. In
the Traditional system of Indian Medicine, it is
known as Gandharvahasta or Castor Oil, and the
abundance of natural compounds in castor oil
possess healing health benefits that are widely used
in Traditional system of Indian Medicine.
Objectives: A comprehensive review has been
made through the Classical Text of Indian System
of medicine. Views of their critics as well as
contemporaries were also taken into consideration
for compilation of Castor Oil formulations.
Material & Methods: The journals, modern books
and internet were also screened during the review
attempt on Castor Oil and their formulations.
Ricinus communis is found throughout India and
has been used medicinally for centuries.
Result: Among the thousands of medicinal plants,
Ricinus communis or castor plant is a widely used
and powerful medicinal plant. More scientifically
based research on its property and various modes
of administration must be conducted. A systematic
review of Castor Oil provides details on its use,
dosage, adverse reactions, and so on. In the current
review, A thorough examination of the evidencebased activity of the formulations mentioned in
Bhaishajya Ratnavali reveals that these
formulations can be used effectively in all diseased
conditions.
Conclusion: This knowledge may be useful in
developing safe and dependable therapeutic
conditions for all types of diseases, which are
currently unavailable on the herbal drug market.
A Review on Lehana as immunomodulation and its role as preventive aspect in children
Authors: Dr. Rekha Dr. Rekha , Singh Chahar Dr. Devendra , Moond Dr. Kamla
Published: December 2024

Introduction: The leading cause of death for
children and young adults worldwide is infectious
diseases, are the main cause of the rise in perinatal
infections, accounting for over 13 million deaths
annually, or one in two deaths in developing
nations, but they are also very common in India,
particularly among children. The Acharya‟s
describe similar methods for administering Lehana,
which involve mixing all the ingredients together
and giving it to the new-born. Therefore, the
primary goal of this article is to review Lehana's
role in immunomodulation and its role as a
preventive measure for children. Material and
Methods: Available literature related to Lehana
were searched from available printed form of
Samhita, and various text books, journals, webbased search engines source were referred for
updated research data. Results: One of the most
significant Lehana‟s mentioned in Ayurveda is
Swarna Prashana, which improves a child's
immunity, physical strength, and metabolism. With
Lehana, sublingual or buccal administration
methods were found to be comparable. The SLIT's
mechanism is comparable to that of the MadhuGhrita prashana or Swarnaprashana Yoga, which
involves administering the antigenic material honey
along with Ghrita for improved absorption and
transport. The addition of Swarna bhasma
strengthens the body's immune system and
functions as an all-around immunomodulatory
therapy. Conclusion: Ayurvedic classics explain
that Swarna, Ghrita, and Madhu have the properties
best suited for administration to children. One way
to think of gold's action is as a general defense
mechanism or reticulo-endothelial system catalytic
stimulation.
Perspectivas de la marcha humana
Authors:   Universidad del Valle, Flórez González Fernando , Mora Olarte Eugenia ,   Universidad del Valle, Perafán González Diana Yasmín ,   Universidad Santiago de Cali, Bolaños Diego Fernando ,   Universidad Santiago de Cali, Giraldo Gutiérrez Yorladiz ,   Universidad Santiago de Cali, Patiño Palma Brayan Esneider ,   Ministerio del Deporte, Calero Saa Pedro Antonio ,   Universidad Santiago de Cali, Suárez Marín Daniel ,   Universidad Santiago de Cali, Rey Peralta Liseth Anyela ,   Universidad Santiago de Cali, Madrid Rodríguez Leidy Johana ,   Universidad Santiago de Cali, Quiguanas López Diana Maritza ,   Universidad Santiago de Cali
Published: December 2024

El estudio de la marcha humana no es una novedad, a lo largo de la historia han existido diversos personajes interesados en compren- der este mecanismo que más allá del desplazamiento corporal, refleja caracteres tales como la personalidad, la cultura y las emociones entre otros aspectos.
BOLAÑO: DE PARTE DE LOS CRÍTICOS
Authors:   Universidad de Lund, Kraus Anna , Ríos Baeza Felipe Adrián ,   Universidad Anáhuac Querétaro, Bejarano Alberto ,   Instituto Caro y Cuervo, Sánchez Noguera Jorge Mario ,   Universidad Santiago de Cali, Íñigo Ainoa ,   Borough of Manhattan Community College, Herrera Pierre ,   Universidad Autónoma Metropolitana Iztapalapa, Rojas Juan Sebastián ,   Universidad Santiago de Cali, Bautista Cabrera Álvaro ,   Universidad del Valle, Arenas Reyes Julio César Augusto ,   Universidad Santiago de Cali
Published: December 2024

En los casi 20 años del siglo XXI, la literatura de Roberto Bolaño se ha situado a escala mundial como una de las más destacadas de Latinoa-mérica.Diversas traducciones al inglés, al francés y al alemán, son una señal de dicha ubicación en la república literaria. Bolaño es un autor de culto para personalidades como Susan Sontag.
Laminaria digitata o el cuerpo híbrido en/de la literatura de Roberto Bolaño
Authors:   Universidad de Lund, Kraus Anna
Published: December 2024

En la narrativa de Bolaño, muchos personajes se molestan con sus cuerpos que no pueden delegar a un segundo plano: los detectives salvajes, Belano y Lima, tienen problemas de estómago, sufren de insomnio e impotencia; en 2666, Fate no deja de vomitar, Morini se desmaya y en una ocasión sufre una pasajera pérdida de la vista, varios otros personajes sudan copiosamente; mientras que César Vallejo, en Monsieur Pain, incluso muere de hipo, porque, al parecer, un complot universal
Veinte años mirando por la ventana: Una revisión crítica de Los detectives salvajes
Authors:   Universidad Anáhuac Querétaro, Ríos Baeza Felipe Adrián
Published: December 2024

Tomando en cuenta ciertas nociones útiles de la sociología de la literatura, el postestructuralismo y la teoría literaria psicoanalítica, este ensayo propone releer de manera crítica y atenta la novela Los detectives salvajes, del chileno Roberto Bolaño. Se resaltan puntos que resultan fundamentales para su inter-pretación veinte años después de haber sido publicada.
Posfacio
Authors:   Universidad Santiago de Cali, Arenas Reyes Julio César Augusto
Published: December 2024

En tiempos de globalización, nuevas tecnologías y cambios; cuando las fronteras se hacen cada vez menos específicas y existe un marcado in-tercambio cultural y lingüístico que se ve representado en las expre-siones de la lengua misma y de la cultura. La literatura como expresión de la lengua y de la cultura no es ajena a estas evoluciones naturales, y consecuente-mente, en el campo de la academia y los grupos disciplinares se ha empezado a repensar qué enseñar y cómo enseñarlo.