bluuebunny/crossref_metadata_2025 huggingface dataset:
Rapid Histological Assessment of Prostate Specimens in the Three-dimensional Space by Hydrophilic Tissue Clearing and Confocal Microscopy
Authors: Peng Yu-Ching , Lin Yu-Chieh , Hung Yu-Ling , Fu Chien-Chung , Chang Margaret Dah-Tsyr , Lin Yen-Yin , Chou Teh-Ying
Published: July 2022

Microscopic examination of biopsied and resected prostatic specimens is the mainstay in the diagnosis of prostate cancer. However, conventional analysis of hematoxylin and eosin (H&E)-stained tissue is time-consuming and offers limited two-dimensional (2D) information. In the current study, we devised a method—termed Prostate Rapid Optical examination for cancer STATus (proSTAT)—for rapid screening of prostate cancer using high-resolution 2D and three-dimensional (3D) confocal images obtained after hydrophilic tissue clearing of 100-µm-thick tissue slices. The results of the proSTAT method were compared with those of traditional H&E stains for the analysis of cores ( n=15) obtained from radical prostatectomy specimens ( n=5). Gland lumen formation, consistent with Gleason pattern 3, was evident following tracking of multiple optical imaging sections. In addition, 3D rendering allowed visualizing a tubular network of interconnecting branches. Rapid 3D fluorescent labeling of tumor protein p63 accurately distinguished prostate adenocarcinoma from normal tissue and benign lesions. Compared with conventional stains, the 3D spatial and molecular information extracted from proSTAT may significantly increase the amount of available data for pathological assessment of prostate specimens. Our approach is amenable to automation and—subject to independent validation—can find a wide spectrum of clinical and research applications.
Feline upper respiratory tract disease – Computed tomography and laboratory diagnostic
Authors: Vekšins Armands
Published: July 2022

Background and Aim: Upper respiratory tract disease (URTD) is prevalent in cats, and diagnosis can be challenging. This study aimed to determine the most common causes of cat URTD in Latvia and describe computed tomography (CT) and laboratory diagnostic findings.

Materials and Methods: The present retrospective study included a total of 94 cats who were diagnosed with URTD. All cats underwent CT, and 50 of them had additional diagnostic tests, such as histology and respiratory infection polymerase chain reaction (PCR) testing.

Results: The most common CT finding was rhinosinusitis (55.32%) followed by nasal neoplasia (26.6%) and nasopharyngeal polyp (14.89%), but in three cats, a cause of respiratory symptoms was larynx neoplasia, nasal dermoid cyst, and an oronasal fistula. PCR test showed that the most cause of rhinosinusitis was Mycoplasma felis. Nasopharyngeal polyp as the primary diagnosis was identified in 14 cats from 3 months to 6 years, with an average age of 1.85 ± 1.915 years, and 54% of cats were female. Nasal neoplasia as a primary CT diagnosis was determined in 25 cats at the age of 5–18 years, with an average age of 10.56 ± 3.416 years. Histology diagnosis included four types of neoplasia – squamous cell carcinoma, sarcoma, adenocarcinoma, and aplastic carcinoma.

Conclusion: This study describes the most common CT and laboratory findings in cats with URTD. Included information will be helpful for general veterinary practitioners and researchers and will update their knowledge on feline URTD.
Load optimization on the performance of combined cycle power plant Block 4 PT Indonesia Power Priok POMU
Authors: Utami Louise Indah , Yuliyani Ika , Suprianti Yanti , Iriani Purwinda
Published: July 2022

Combined cycle power plant (CCPP) is a closed-cycle power plant, where the heat from the gas turbine’s (GT) exhaust gas will be streamed to the heat recovery steam generator (HRSG) to be utilized by steam turbine (ST). CCPP Block 4 (Jawa-2) PT Indonesia Power Priok POMU has an installed capacity of 880 MW, consists of 2 GT units (301.5 MW each) and 1 ST unit (307.5 MW). The performance of a power plant depends on its load, as the efficiency of the turbine generator is low when operated at low loads. The data as of July 2019 showed that 2.2.1 (2 GT, 2 HRSG, 1 ST) configuration has been used in three conditions where the CC net load was around 30 - 45 %, which in fact could be compensated by the 1.1.1 (1 GT, 1 HRSG, 1 ST) configuration. This resulted in a decrease of the CC net efficiency up to 21.34 %. The optimization that can be done is to change the load configuration from 2.2.1 to 1.1.1 at 0 - 50 % of CC net load through simulations, by including the influence of the GT and HRSG start-up processes. The result of this optimization is that the CCPP performance increases due to higher performance of each turbine generator. Thus, the optimization results during July 2019 provided energy saving of 1,146.09 MMBTU or equivalent to cost saving of IDR 152,249,551.76.
Fabrication of nitrate ion sensor based on conductive polyaniline doped with nitrate using thick film technology
Authors: Charlotha Charlotha , Manurung Robeth Viktoria , Debataraja Aminuddin , Dwisaputra Indra , Subkhan Subkhan , Syamsu Iqbal
Published: July 2022

Nitrate is one of the nutrients that can give an effect on the environment if it is applied in excess. It is also easily soluble in water and it has the potential to be a pollutant in groundwater by the over-process of fertilizer. Therefore, it needs a detected component to give the right measure for nitrate in the soil, called a nitrate ion sensor. It consists of three electrodes configuration, namely, working, counter, and reference electrodes with conductive polyaniline doped with Nitrate (NO₃‾) which is fabricated by thick film technology. In previous research, acidic media was used as a solvent for polyaniline, while this research used water (H2O) solvent. The result of characterization showed that particles were distributed evenly on the sample with the form of particles being small balls with a dimension of 0.18 µm and the percentage of atomic elements being: 91.96 % carbon, 3.14 % nitrogen, and 4.9 % oxygen. The performance of sensors was investigated using potentiostat with four concentrations of nitrate standard solution. The result showed good response with a voltage range in each concentration of nitrate standard solution being 0.5002 Volt (10 mg/l), 1.3552 Volt (20 mg/l), 1.1208 Volt (50 mg/l), and 0.8963 Volt (100 mg/l). It was found that nitrate sensors with nitrate-doped conductive polymer, polyaniline, as the sensitive membrane responded well to detecting nitrate elements in precision farming and the sensitivity showed that for every 1 mg/l concentration in nitrate standard solution, the voltage increases by 0.0007.
Case Control Study to Evaluate Tear Film Function and Ocular Surface Disorder in Diabetic Patients
Authors: Samreen Arif  , Jyoti Tulsani  , Sajid Naqvi
Published: July 2022

BACKGROUND

Diabetic retinopathy and early development of cataracts are well-known ocular complications of long-standing diabetes. In recent years various researchers have reported ocular surface disorders, particularly dry eyes in diabetic patients which if left untreated may result in a variety of corneal complications. These ocular surface disorders can be clinically diagnosed by performing a detailed slit lamp examination, Schirmer's test and tear film break-up time. Our study intended at assessing tear film and ocular surface disorders in diabetic patients and study tear film function in them and compare it with non-diabetic patients.

METHODS

A comparative cross-sectional study was done on 100 diabetic and 100 non-diabetic patients > 30 years of age visiting OPD of health centre of tertiary care hospital of Central India. Clinical data and detailed clinical history were obtained from all subjects through direct patient interviews and reviewing of their medical records followed by a comprehensive ocular examination that included best-corrected vision, slit lamp examination, and Tear Film break up time (TBUT) & Schirmer test.

RESULTS

In our study, mean TBUT was found to be significantly reduced in diabetics (15.94 ± 3.8) as compared to non-diabetics (20.13 ± 6.6). No significant difference was found in the Schirmer test reading between diabetics (17.13 ± 3.20) and non-diabetics (19.20 ± 6.23). Diabetic male patients had significantly decreased mean TBUT & mean Schirmer test readings as compared to diabetic females. Mean Schirmer reading & Mean TBUT were lowest in a patients having > 20 years of DM and highest in patients having < 5 years of DM. No positive correlation was found between HbA1c (Glyosylated Haemoglobin) and diabetic retinopathy with TBUT/ Schirmer test readings.

CONCLUSIONS

Our study showed that the tear film stability was found to be affected in diabetic patients, as compared to non-diabetic subjects as evident by the lower level of TBUT in diabetic patients. Significantly reduced TBUT with no significant difference in Schirmer test reading in diabetic as compared to non-diabetic subjects might be due to a decrease in basal secretion with normal overall tear secretion. The absence of subjective symptoms of dryness in spite of decreased TBUT in the diabetic group might be due to a decrease in corneal sensitivity caused by diabetic peripheral neuropathy in diabetic patients. There was an increase in the prevalence of DES with an increasing duration of DM. Rheumatoid arthritis was found to be a risk factor for DES. Diabetic males were found to be at risk for developing dry eye syndrome. Hence it can be concluded from our study that every diabetic patient should undergo a comprehensive eye examination which should include various tests for dry eye assessing multiple tear parameters.
SEPA Based Flap for Covering Defect after Adult Exstrophy Epispadias Repair
Authors: Deepak Bolbandi  , Raghuveer  , Mayank Agarwal
Published: July 2022

INTRODUCTION

Bladder exstrophy is a complex, rare disorder that affects the foetus in utero. Here the abdominal wall is not fully formed, leaving the pubic bones separated and the bladder exposed in the lower abdominal wall.

METHODOLOGY

Single-stage reconstructive and repair surgery was undertaken in adults diagnosed with bladder exstrophy epispadias complex. The superficial external pudendal artery flap was considered for covering the defect after extensive reviews and discussion.

CONCLUSION

An uneventful surgery with recovery and a two-year follow-up post-surgery did not account for any complications following the procedure. This shows that the superficial external pudendal artery flap can be considered a favourable option for urologists in the repair of bladder exstrophy epispadias complex when undertaken in a single sitting surgery, especially in adults.

MeSH Terms

Bladder Exstrophy, epispadias repair, superficial external pudendal artery, axial-pattern flap.
Análise de tendência de concentração de material particulado atmosférico e efetividade de políticas públicas
Authors: Marinho Lucas Veloso , Nogarotto Danilo Covaes , Pozza Simone Andrea
Published: July 2022

A poluição atmosférica é um problema ambiental que provoca efeitos nocivos, tanto a curto quanto a longo prazo, gerando por isso, constante preocupação dos gestores, por todo o mundo. Este trabalho objetivou verificar tanto a tendência de comportamento na concentração de material particulado inalável (MP10), como a efetividade de políticas públicas na busca pela redução e controle deste poluente. Dois municípios paulistas, com características distintas de desenvolvimento, industrialização e expansão urbana foram usados como estudos de caso. Os dados de Marília (entre 2009 e 2020) e de Paulínia (entre 2002 e 2020) foram coletados da plataforma QUALAR, da Companhia Ambiental do Estado de São Paulo (CETESB) e tratados com o auxílio do pacote Openair, do Software R. Foi possível verificar que inverno e primavera apresentaram concentrações mais elevadas de MP10, quando comparado às estações de verão e outono, assim como evidenciar que a sua concentração foi bem menor aos finais de semana. Os dados referentes as concentrações de MP10 dos municípios de Marília e Paulínia, quando confrontados ao Decreto Estadual nº 59.113, indicaram que, a partir de 2013, as concentrações deste poluente apresentaram consideráveis reduções, muito provavelmente relacionadas a ações e práticas de políticas públicas e pela atuação do órgão ambiental estadual. Para que se atinja as novas diretrizes da OMS, sugere-se que, novas medidas sejam adotadas.
Effects of Three Anesthesia Methods on Inflammation, Oxidative Stress, Analgesia
and Cognition in Elderly Patients Receiving Hip Replacement
Authors: Jizheng Zhang  , Xiaohua Sun  , Yan Liu  , Xiaochen Gui  , Wanlu Ren
Published: July 2022

The study aimed to investigate the effects of different anesthesia methods on the analgesia,
inflammation and oxidative stress levels and cognitive function in elderly patients undergoing hip
replacement. 100 elderly patients requiring hip replacement and admitted to Tianjin Hospital from
March 2017 to March 2019 were enrolled and divided into group A (n=35, general anesthesia with
endotracheal intubation), group B (n=35, epidural anesthesia) and group C (n=30, general anesthesia
with endotracheal intubation + epidural anesthesia). The basic vital signs, inflammatory factors, stress
response indicators and cognitive function changes were compared among three groups. Additionally,
the effects of three different anesthesia methods were analyzed based on the differences in postoperative
analgesic effect, extubation time and recovery time. The vital signs [systolic blood pressure (SBP),
diastolic blood pressure (DBP) and heart rate (HR)] were lower in group C than those in group A and
group B after surgery (p<0.05). The VAS score at 12 h and 24 h after surgery was lower than that at 3 h
after surgery (p<0.05). Group A and B had increased levels of these inflammatory factors after surgery
compared with those before surgery. Postoperative extubation time, eye-opening time upon calling and
recovery time were significantly shorter in group C than those in groups A and B (p<0.05). The
oxidative stress indexes in group C were remarkably lower than those in groups A and B (p<0.05). The
MMSE score was decreased in groups A and B after surgery compared with that before surgery
(p<0.05). General anesthesia combined with epidural anesthesia applied in elderly patients undergoing
hip replacement achieves a good anesthetic effect and is able to stabilize the vital signs and stress levels
of patients and improve postoperative analgesic effect and cognitive function, which is worthy of
popularization in clinical practice.
Influence of Dexmedetomidine on Cognitive Function and Inflammatory Factors in
Rats and Analysis of Its Molecular Mechanism after Cardiac Surgery under
Cardiopulmonary Bypass
Authors: Jingjing Yang  , Xiaoyan Zheng  , Shuai Zhang  , Hanwei Wang
Published: July 2022

The study aimed to explore the influence of Dexmedetomidine (Dex) on cognitive function and
inflammatory factors in rats after cardiac surgery under cardiopulmonary bypass (CPB). For this
purpose, 30 healthy male SD rats were reared in a quiet and clean environment with alternating light for
12 hours. They were rolled randomly into 3 groups, each with 10 rats, namely the control (Ctrl) group,
the experimental group, and the Dex group. The rats in the Ctrl were not treated, and the rats in the
experimental group were intraperitoneally injected with 50μg/kg saline. After that, cardiac surgery was
performed under CPB. Rats in the Dex group were injected with 50 μg/kg Dex intraperitoneally and
underwent cardiac surgery under CPB. The Morris water maze (MWM) experiment was performed to
test the learning and memory abilities and spatial positioning abilities of SD rats. Enzyme-linked
immunosorbent assay (ELISA method) was adopted to detect the contents of TNF-α, IL-6, and IL-1β.
Fluorescence quantitative PCR was applied to determine the mRNA expression levels of TNF-α, IL-6,
and IL-1β in the hippocampus. Results showed that in the MWM experiment, in contrast with the Ctrl,
the escape latency of the experimental group and the Dex group after surgery were prolonged (P<0.05),
and the times they crossed platforms reduced (P<0.05). In contrast with the experimental group, the
escape latency of the Dex group shortened, and the times they crossed platforms increased. ELISA
suggested that in contrast with the experimental group, the concentrations of TNF-α, IL-6, and IL-1β in
the Ctrl decreased (P<0.05), and those in the Dex group decreased slightly. In the fluorescence
quantitative PCR experiment, in contrast with the experimental group, the mRNA expression levels of
TNF-α, IL-6, and IL-1β in the Ctrl increased, and those in the Dex group decreased slightly. Then Dex
can improve the cognitive dysfunction of rats undergoing cardiac surgery under CPB, and its molecular
mechanism may be to reduce the inflammation around the heart and hippocampus.
Relationship between the Characteristics of Vaginal Secretion, Reproductive Immune
Antibody and Infertility
Authors: Huabin Cao  , Lu Wang  , Huanhuan Wu
Published: July 2022

Infertility is still a hot topic in the field of reproductive medicine. In this paper, the detection of vaginal
secretions and the positive rate of serum reproductive immune antibody in infertile women and normal
pregnant women were used to explore the correlation between infertility and the two, so as to provide an
effective scientific basis for the diagnosis and treatment of infertility. In this paper, 80 infertile patients
(experimental group) and normal pregnant women (control group) were selected for the experiment.
Real-time PCR was used to detect vaginal secretion and enzyme-linked immunosorbent assay. The
results showed that the positive rates of UU and CT were 42.5% and 40%, respectively. The positive
rate of the control group was 8.8% (Uu) and 7.5% (CT). In addition, the positive rates of ANA and
AsAb in the experimental group were 40% and 44%, respectively, and those in the control group were
7.5% and 8.8%, respectively, with a significant difference (P<0.01). The correlation coefficients
between the two antibodies and the occurrence of infertility were 0.501 (ANA) and 0.663 (AsAb), and
there was a correlation (P<0.05).
The effect of miR-138 on the proliferation and apoptosis of breast cancer cells
through the NF-κB/VEGF signaling pathway
Authors: Hongbing Cheng  , Liangji Chen  , Zhenyu Fang  , Qian Wan  , Zhuo Du  , Nanshan Ma  , Genxin Guo  , Wenjing Lu
Published: July 2022

The analyze the effect of miR-138 on the proliferation and apoptosis of breast cancer cells through the
NF-κB/VEGF signaling pathway is the Objective of this experiment. For this aim, the endometrial stem
breast cancer cell line MCF-7 was cultured in vitro, and the overexpression mimic miR-138 mimics and
the inhibitor anti-miR-138 were transfected into the endometrial stem breast cancer cell line MCF-7,
which was set to overexpress miR-138 group and interfere with miR-138, and set up negative control of
overexpression and negative control of inhibitor. Observe the cell proliferation and apoptosis ability of
each group, and the changes in tumor necrosis factor-α (TNF-α), interleukin 1β, 6, 18 (IL-1β, IL-6, IL-
18) levels, and compare the Bax of each group, NF-κB, VEGF protein expression level. Results showed
that the proliferation ability of the miR-138 overexpression group was significantly lower than that of
the miR-138 overexpression control group (P<0.05); the proliferation ability of the miR-138
interference group was significantly higher than that of the miR-138 interference control group
(P<0.05). The apoptosis rate, caspase-3 and caspase-9 expression levels of the miR-138 overexpression
group were significantly higher than those of the miR-138 overexpression control group (P<0.05); the
apoptosis rate, caspase-3 and caspase-9 expression levels of the miR-138 interference group were
significantly lower than those of the miR-138 interference control group (P<0.05). The expression levels
of IL-1 β, IL-6, IL-18 and TNF - α in the miR-138 overexpression group were significantly lower than
those in the miR-138 overexpression control group (P < 0.05). The protein expression levels of Bax,
NF-κB and VEGF in the miR-138 overexpression group were significantly lower than those in the miR-
138 overexpression control group (P < 0.05); the protein expression levels of Bax, NF-κB and VEGF in
the miR-138 interference group were significantly higher than those in the miR-138 interference control
group (P <0.05). The proliferation ability of the miR-138 overexpression group was significantly lower
than that of the miR-138 overexpression control group (P < 0.05); the proliferation ability of the miR-
138 + NF-κB overexpression group was significantly higher than that of the miR-138 overexpression
group (P<0.05). The apoptosis rate of the miR-138 + NF-κB overexpression group was significantly
lower than that of the miR-138 overexpression group (P < 0.05). Then MiR-138 can significantly inhibit
the proliferation of breast cancer cells, promote apoptosis, and regulate the expression of inflammatory
factors in the cells. It is speculated that the related mechanism may be related to the negative regulation
of the NF-κB/VEGF signaling pathway.
PMN Apoptosis Induced by SNHG11 through the Inhibition of Endotoxin-induced
Acute Lung Injury NF-κB Pathway
Authors: Wenhui Hu  , Yaping Ying  , Lihong Jin  , Lingling Chen  , Tingmin Zhou  , Xiaohong Jin
Published: July 2022

To investigate the impacts of small nucleolar RNA host gene 11 (SNHG11) on nuclear factor kappa-B
(NF-κB) pathway and polymorphonuclear granulocyte (PMN) apoptosis in rats with endotoxin-induced
acute lung injury (ALI). Forty rats were the experimental subjects. They were randomly grouped as a
control group (Group C), an endotoxin group (Group E), an inhibitor group (Group I), and an activator
group (Group A), with 10 rats in each group. The endotoxin-educed ALI rat model was built. Arterial
Blood Gas Test (ABGT) was performed, and the Wet/Dry (W/D) ratio of lung weight was determined.
The pathological variations in rat pulmonary tissues were scrutinized and scored. PMN in peripheral
blood was isolated; its apoptosis was assessed, and its total NF-κB p65 and p-NF-κB p65 expressions
were assessed. The expression of SNHG11 mRNA in pulmonary tissues was assessed. Results:
Compared to Group C, the W/D ratios and pathological scores of Group E, Group I, and Group A
boosted notably (P <0.05), while their ABGT indicators and PMN apoptosis rates dropped (P <0.05).
Compared to Group E and Group I, the W/D ratio and pathological score of Group A dropped notably
(P <0.05), while its ABGT indicators and PMN apoptosis rate boosted (P <0.05). Compared to Group C,
the p-NF-κB p65 and SNHG11 expressions were boosted in Group E, Group I, and Group A (P <0.05);
compared to Group E and Group I, the p-NF-κB p65 and SNHG11 expressions in Group A dropped (P
<0.05). SNHG11 could relieve endotoxin-induced ALI, which might be associated with the acceleration
of PMN apoptosis and the inhibition of the NF-κB pathway.
Business Student Perceptions of Online versus Face-to-Face Education Given Self-Reported Technology Level and Number of Online Courses Web Appendix
Authors: Fish Lynn A. , Snodgrass Coral R.
Published: July 2022

Through an ongoing study at an AACSB Jesuit, Catholic University with a strong focus on teaching, business student perspectives regarding online versus face-to-face courses indicate that students prefer face-to-face classes. Researchers have noted changes in student perspectives over time. A student’s perception of their own technological understanding may impact upon their perception of online and face-to-face education. Past research demonstrated a difference in student perceptions as the student took more online courses. This research explores the impact of a student’s self-reported technological understanding and taking more online courses. This research has implications for instructors and administrators.
Pembinaan Prestasi Olahraga Atletik di Kabupaten Kendal Tahun 2019
Authors: Putri Eka Erisza , Suripto Agus Widodo
Published: July 2022

Aim of this study is to determine the implementation of installation, breeding, and coaching in the athletic sports achievement at PASI Kendal Regency. This study used a qualitative approach research method. The subjects of this study were administrators, coaches and athletes. The techniques of collecting data in this study were through observation, interviews, and documentation. The techniques of analyzing data used data collection, data reduction, and drawing a conclusion. The validity of the data in this study used data triangulation. The results showed that the stages of installation and breeding in the athletic sports at PASI Kendal Regency were carried out by introducing athletic sports during open selection activities or through direct observation towards the school. The athletic sports PASI in Kendal Regency have quite good achievements because they are supporting by infrastructure, a qualified trainers who have Level 3 IAAF certificates, and there are intensive and extra for outstanding athletes. The conclusion of this study is the development of athletic sports achievement in PASI Kendal Regency year 2019 included as good criteria
Profil Atlet Pelatda Hoki Jawa Tengah Dalam Persiapan PON Papua XX Tahun 2021
Authors: Risdiyanti Winda , Hartono Mugiyo
Published: July 2022

Latar belakang penelitian ini adalah kondisi fisik merupakan bagian penting dalam perolehan prestasi maksimal, karenanya mengetahui kondisi fisik sangat diperlukan. Tujuan yang ingin dicapai dalam penelitian ini adalah untuk mendeskripsikan profil atlet pelatda hoki Jawa Tengah dalam persiapan PON Papua XX Tahun 2021. Metode pengumpulan data menggunakan metode tes dan pengukuran kondisi fisik, ketrampilan dasar dan indeks massa tubuh. Populasi penelitian ini adalah atlet Pelatda hoki Jawa Tengah sebanyak 20 atlet (10 atlet putra dan 10 atlet putri). Teknik pengambilan sampel menggunakan total sampling. Variabel penelitian ini adalah 1), komponen kondisi fisik, 2) komponen ketrampilan dasar, 3) komponen indeks massa tubuh. Teknik analisis data dengan menggunakan statistik deskriptif. Hasil penelitian menunjukan bahwa profil atlet pelatda hoki Jawa Tengah 2020 komponen fisik keseluruhan 12 item tes fisik yang diujikan di dapatkan 3 item penilaian baik, 6 item cukup, 1 item kurang, 2 item kurang sekali, komponen ketrampilan dasar 3 item tes fisik yang diujikan di dapatkan 1 item penilaian baik, 1 item baik sekali, 1 item baik sekali, komponen indeks massa tubuh tes yang diujikan di dapatkan kategori ideal. Simpulan dari hasil penelitian pada pelatda hoki Jawa Tengah tahun 2020 dapat dikatakan kurang maksimal dan masih bisa ditingkatkan ke dalam kategori baik sekali, melalui program latihan yang lebih spesifik mengenai latihan fisik dan teknik serta asupan gizi. berdasarkan hasil tes profil atlet pelatda putra dan atlet putri.
Motivasi Masyarakat Terhadap Aktivitas Car Free Day di Alun-alun Kabupaten Temanggung
Authors: FITRIANI RIZQI WITARI
Published: July 2022

The purpose of this research to describe the community's motivation to sport activities In the Car Free Day Square of  Temanggung district. The research method used Is a survey through a quantitative approach. Data collection Is done by observation, Interviews, and questionnaires. The results showed that the community's motivation to exercise due to physiological needs had a percentage of 23,3%, a safety requirement of 23,03%, a social need of 19.30%, the need for an award of 12,55%, and self-actualisation requirement of 21,49%. For the  people of Temanggung distict,it is hoped that they can make as good as possible of  Car Free Day activity because the Car Free Day  is a means of self-actualization which is very beneficial for improving health, physical fitness, social and self-actualization. Then for the local government to expand the hygiene facilities such as trash cans and handwashing places and for organizers or community leaders still provide the best service so that the community Is Increasingly motivated to exercise In the Car Free Day of Temanggung District Square.
Sri Indarti Manajemen Pengelolaan Penyedia Jasa Instruktur Senam Aerobik Di Kabupaten Demak
Authors: Indarti Sri
Published: July 2022

The purpose of this study was to determine the management of service providers and the satisfaction of users of aerobic infrastructure services in Demak Regency. This study used descriptive qualitative method. The location of this research is an institution that is a provider of aerobic exercise instructor services in Demak Regency. The data collection methods in this research are: observation, interview, documentation, from each instrument the data collection method can be described. The research instrument used an interview guide, observation (observation) and documentation. Data analysis techniques used qualitative research conducted before entering the field, during the field and after completion of the field. The results showed that the results of the research in four locations were related to the management of aerobic gymnastics instructor service providers in Demak Regency which consisted of five functions, first the planning was running smoothly and well, secondly the organization was running poorly, the three movements were running well, the fourth was running supervision. well, and the five customer satisfaction is good.
Manajemen Outbound Taman Wisata Matahari Di Cisarua Kabupaten Bogor tahun 2020
Authors: Safitri Wiwi , Mulyono Aris
Published: July 2022

Wiwi Safitri. 2021. Management Analysis of Outbound Activity in Matahari Tourism Park Cisarua Bogor 2020. Skripsi, Department of Health and Recreation Physical Education / S1 Faculty of Sport Science, State University of Semarang. Advisor Aris Mulyono, S, Pd., M, Pd.Keywords: Management, Outbound,Taman Wisata Matahari Recently, the enthusiasm of the community, organizations and companies has been busy organizing recreational activities together as an effort to improve the performance and performance of their members or employees. One of them is an activity in the form of Outbound training. The development of the sports industry is currently very much in demand by private entrepreneurs, especially outbound. This Matahari Tourism Park is one of the tours with a concept of carrying outbound activities as a concept of recreation and education for the community. The problem of this research is how to implement the management function in the management of Taman Wisata Matahari in the presence of the same business competition in other places. Manager's leadership, outbound trainers and visitors. Data analysis uses focus data selection to answer the problem formulation (data reduction), which is arranged briefly (display data), and develops after being in the field (verification). The results showed that the planning function of the solar tourism park has its own vision and mission of the company which plans are long-term and short-term. Taman Wisata Matahari has an organizing line (leadership, staff, functional). The process of recruiting employees is always prioritized to support good and efficient organizational activities. The existence of good promotions, welfare, warning letters (SP) to dismissal if they do not comply with all existing regulations and retired employees who are always carried out by the Taman Wisata Matahari. Motivation for employees is carried out by HRD leaders to improve employee performance. Evaluating activities and employees is always the main thing to assess the performance of the system. Based on the above results it can be concluded that the management (planning, organizing, employees, motivation and supervision) at Taman Wisata Matahari has good and neat management. Management needs to carry out intensive supervision both in the office and in the field, this is to reduce the occurrence of errors in management implementation
Manajemen Pembinaan Prestasi Klub Bola Voli Mitra Kencana Semarang Tahun 2021
Authors: Nailufar Nabila , Hartono Mugiyo
Published: July 2022

Fokus kajian penelitian ini meliputi pengelolaan manajemen, pelaksanaan program pembinaan, atlet, pelatih, sarana, prasarana, dan prestasi. Tujuan peneliti untuk mengatahui manajemen pembinaan pada klub tersebut.

Peneliti menggunakan pendekatan deskriptif kualitatif. Pengumpulan data menggunakan metode observasi, wawancara, dokumentasi. Sumber data penelitian adalah pengurus, pelatih, dan atlet Klub Mitra Kencana Semarang. Subyek dalam penelitian adalah 1 pengurus, 3 pelatih, dan 8 atlet Klub Mitra Kencana Semarang.

Hasil penelitian ini adalah pengolahan manajemen dari berbagai aspek sudah sesuai dengan program kerja yang telah dibuat pada klub.

Simpulannya klub ini terstruktur dengan baik dan memiliki prestasi yang baik. Saran yang diberikan yaitu: 1) Pengurus dan pelatih perlu adanya penambahan anggota, 2) Lebih diperketat dalam kedisiplinan atlet agar lebih bertanggungjawab dalam mengikuti program latihan yang diberikan oleh pelatih, 3) Pendanaan senantiasa menjalin kerjasama dengan pihak-pihak luar, 4) Program latihan disesuaikan dengan kondisi eksternal atlet, 5) Melengkapi kekurangan sarana dan prasarana seperti gedung olahraga, 6) Perlu peningkatan prestasi agar sampai tingkat nasional.
Tingkat Penguasaan Materi PJOK dalam Proses Pembelajaran Secara Daring pada Siswa SD di Desa Jono Kecamatan Tawangharjo Kabupaten Grobogan 2021
Authors: Siwi Alif Haryo , Hartono Mugiyo
Published: July 2022

Abstak

Penelitian ini menggunakan pendekatan kuantitatif dengan metode survei, teknik pengambilan sampelnya berupa total sampling berjumlah 71, pengumpulan datanya menggunakan angket. Analisis data menggunakan analisis SPSS berupa deskriptif statistik. Penelitian ini bertujuan untuk mendeskripsikan Tingkat pengetahuan materi penjasorkes Dalam Proses Pembelajaran Secara Daring Pada Siswa SD Di Desa Jono Kecamatan Tawangharjo Kabupaten Grobogan Tahun 2021. Hasil penelitian menunjukkan bahwa tingkat pengetahuan materi penjasorkes siswa Sekolah Dasar di desa Jono Kecamatan Tawangharjo Kabupaten Grobogan selama pembelajaran daring berada pada kategori  “sangat tinggi” sebesar 0% ( 0 siswa), “tinggi” sebesar 38,03%( 27 siswa), “sedang” sebesar 22,54% (16 siswa), “rendah” sebesar 36,62%(26 siswa), “ sangat rendah” sebesar 2,82% (2 siswa). Kesimpulan adalah tingkat pengetahuan materi Penjasorkes siswa SD Di Desa Jono berada pada kategori “tinggi” dengan jumlah 27 siswa.

Abstract

This study uses a quantitative approach with a survey method, the sampling technique is a total sampling of 71, the data collection uses a questionnaire. Data analysis used SPSS analysis in the form of descriptive statistics. This study aims to describe the level of physical education material knowledge in the online learning process for elementary school students in Jono Village, Tawangharjo District, Grobogan Regency in 2021. The results showed that the level of physical education material knowledge of elementary school students in Jono Village, Tawangharjo District, Grobogan Regency during online learning was at category "very high" by 0% ( 0 students), "high" by 38.03% (27 students), "medium" by 22.54% (16 students), "low" by 36.62% (26 students ), “very low” by 2.82% (2 students). The conclusion is that the level of knowledge of physical education material for elementary school students in Jono Village is in the "high" category with a total of 27 students.
How to Retain Rural Preschool Teachers?
Authors: Luo Yuhua , Yuan Suonian , Zhou Longjun
Published: July 2022

As a result of the accelerated urbanization and the improved remunerations of urban teachers, a large number of rural teachers have been pursuing employment in urban areas, resulting in a severe shortage of rural teaching staff. This phenomenon is particularly pronounced in developing countries. Disadvantages in rural school working and living situations such as low pay, poor living conditions, heavy workloads, limited professional development has made teacher recruitment and retention extremely challenging tasks. The unbalanced urban-rural distribution of teachers, especially high-quality teachers, have become barriers to rural education development and further exacerbated the disadvantaged situations of rural students.
A technique for external beam radiotherapy to the eyelid without the need for an internal eye shield
Authors: Gorjiara Tina , Conway Aoife , Sullivan Joanne , Guitera Pascale , Petsoglou Con , Conway R. Max , Illie Vlad , Fogarty Gerald B.
Published: July 2022

Cancer of the eyelids is difficult to treat. Surgery can lead to tissue loss. Superficial radiotherapy (SXRT) can be used in this scenario, but each fraction requires topical ophthalmic local anaesthetic and the insertion of an internal eye shield (IES) to protect the radiation sensitive anterior structures from the incident beam during beam-on time. The use of an IES comes with challenges. A technique was developed to avoid the IES based on the ability of selected cooperative patients to move the anterior structures out of the incident beam during beam-on time. We present two cases in which this technique was used. Case 1 involves the lower eyelid and case 2 the upper eyelid. Case 1 was a 69-year old, immunosuppressed woman needing definitive SXRT for lentigo maligna (LM) of the lower eye lid. She was treated using the new non-IES technique to a total dose of 50 Gy in 25 fractions using a 100 kV beam from a superficial Xstrahl 300 radiotherapy unit (Xstrahl, Surrey, UK). In vivo dosimetry (IVD) measured during a fraction on the posterior of the external eye shield located above the anterior structures showed that the transmitted dose through the external eye shield was less than ten percent of the dose applied. The patient developed conjunctivitis during SXRT that responded to topical antibiotics. Ophthalmology review five months post SXRT showed no change in eye function from baseline. Reflectance confocal microscopy (RCM) eight months after SXRT showed no LM. Case 2 was a 72-year old woman needing post-operative radiotherapy (PORT) for sebaceous cell carcinoma (SebC) of the upper eyelid. She was treated with 60 Gy in 30 fractions at 5 fractions per week with 100kV SXRT using the new non-IES technique. All the treatment was delivered on time. As per Case 1, IVD under the external eye shield showed the transmitted dose was ten percent of the dose applied. Ophthalmology review pre- and post-RT showed no change in eye function. She remains in complete remission six months after the end of PORT. The new non-IES technique is safer and quicker and simplifies the workflow. This has become the standard technique in our department for treating eyelids with SXRT. Multidisciplinary care involving an ophthalmologist pre- and post-SXRT is advised.
Does psoriasis need more radiation dose to clear recalcitrant plaques? A case series of lesions from a single subject
Authors: Fogarty Gerald B. , Moutrie Zoe , Cusi Mel , Gibbs Rachel , Allende Alexandra
Published: July 2022

Psoriasis vulgaris is a chronic benign disease of the whole thickness of the epidermis with symptomatic plaque formation impacting quality of life. Relatively low doses of fractionated radiotherapy (RT) have been used in the past to a total dose of four to six Gray (Gy). We present the case of an older male with seven recalcitrant plaques each treated with the same prescribed dose of RT. Superficial radiotherapy (SXRT) with a 100kV beam from a Xstrahl 300 machine to a total dose of 20 Gy in 10 fractions (#s) at five #s per week was used for six areas - four on the scalp and one on each elbow. At six months post treatment, four scalp areas had a continuing complete response (CR) whilst the elbows had a continuing partial response (PR). A seventh area, measuring 21 x 16cm on the lower back, was treated with volumetric modulated arc therapy (VMAT) using six megavoltage photons (MV) at the same prescribed dose. At four weeks, an infield CR was observed, but at eight weeks there was some infield recurrence. Pre- and post-RT biopsies from this field were compared. In the VMAT area with clinical recurrence, RT caused a histological PR. In the VMAT area with clinical CR, there was no histological evidence of disease. These findings raise radiobiological questions. Was the difference in clearance due to lower disease burden, kilovoltage backscatter from bone giving a higher relative dose, a difference in oxygenation or chronic sun exposure of tissues, or a difference in the relative biological effectiveness (RBE) between SXRT (1.2) relative to MV photons (1.0)? We recommend that future studies of RT in psoriasis start with 20Gy in 10#s, preferably with a modality that can penetrate the whole plaque epidermis, which can be quite thickened in patients suffering from psoriasis.
The survey and identification of the effect of sports activities on non-active and active students’ mental health
Authors: Bakhshalipour Vahid
Published: July 2022

Mental disorders have harmful effects on individuals and society. A person who has not mental health suffers physical and mental symptoms, isolation, headache, worry, depression, anxiety, difficulty falling asleep and daily dysfunction. The purpose of this study was to survey and identify the effect of sports activities on non-active and active students’ mental health. This study is a descriptive and ex-post facto research. The sample size was included 480 female students that they were randomly selected. The instrument of this study was included Goldberg’s General Health Questionnaire-28 (GHQ-28).The collected data were classified by descriptive statistical methods (percentage, mean, standard deviation) and were analyzed by the T-test and the Chi-Square Test. The SPSS software (version 21) was used for data analysis (α≤0.05).Married athlete students’ general health score was 19.36, married non-athlete students’ general health score was 20.11, single athlete students’ general health score was 19.16 and single non-athlete students’ general health score was 21.11.Sport activities are a valuable tool for maintaining mental health and those are effective on the prevention of mental disorders. The university authorities are recommended to increase the time of sports activities, so that students have more physical activities.
Small-sided games activities with external wildcard soccer players
Authors: Sannicandro Italo , Cofano Giacomo
Published: July 2022

Aim: The Small-Sided Games (SSG) is technical exercises presented as modified games by coaches and conditioning trainers according to the objective of the training session. The aim of the study is to evaluate and compare the external load of the professional player using GPS devices and to describe the speed run and power events in 6vs6 and 7vs7 SSG with external wildcard players. Methods: 14 professional soccer players Results: The study shows that values ​​of average speed, average power and the power events number were statistically significant in 6vs6 versus 7vs7 (p<0.05); the low intensity (p<0.05) and moderate intensity travel volumes are higher in 6vs6, while the high intensity runs and the sprint number are clearly higher in 7vs7 (p<0.001). Conclusion: The results showed that the two SSG formats determine very different external workload in professional soccer players. The 7vs7 format shows a greater sprint number while the 6vs6 imposes average running speeds up to medium intensity but does not require, if not to a very small extent, high speed and sprint performance.
Dual Antiplatelet Therapy for 3 or 12 Months in Patients with Non-ST-elevation MI/Unstable Angina or ST-elevation MI: Analysis of the REDUCE Trial
Authors: Wan Ahmad Wan Azman , Benit Edouard , Legrand Victor M , Yahya Achmad Fauzi , Tan Huay Cheem , Rifqi Sodiqur , Abdul Kader Muhamad Ali SK , Pironi Bruno , de Winter Robert J , Tam Chor-Cheung Frankie , Ligtenberg Eric , De Luca Giuseppe , Suryapranata Harry
Published: July 2022

Background: The aim of this subanalysis of the REDUCE (Short-term Dual Antiplatelet Therapy in Patients with ACS Treated with the COMBO Dual-therapy Stent) trial was to evaluate differences between non-ST-elevation MI/unstable angina (NSTEMI/UA) patients and ST-elevation MI (STEMI) patients in terms of patient characteristics, procedures and outcomes. Methods: In the REDUCE trial, 1,496 acute coronary syndrome patients undergoing successful COMBO stent implantation were randomised to 3 or 12 months of dual antiplatelet therapy (DAPT) treatment. In total, 789 (52.8%) patients had NSTEMI/UA and 706 (47.2%) had STEMI. For this analysis, NSTEMI/UA patients (n=789) were compared with STEMI patients (n=706). Results: In the analysis of the NSTEMI/UA and STEMI cohorts comparing 3-month DAPT (751 patients) and 12-month DAPT treatment (745 patients) there were no statistically significant differences in the primary endpoints of all-cause mortality, MI, stent thrombosis, stroke, target vessel revascularisation or bleeding (Bleeding Academic Research Consortium [BARC] II, III, V) at 360 and 720 days between the two cohorts. Comparing the overall primary endpoints in the NSTEMI/UA cohort, 3-month DAPT was better than 12-month DAPT (9.6% versus 10.0% at 360 days and 12.1% versus 15.0% at 720 days). In the STEMI cohort, 12-month DAPT was better than 3-month DAPT (8.4% versus 11.0% at 720 days). Conclusion: For NSTEMI/UA patients, a numerically lower occurrence of outcomes was observed with 3-month DAPT at 360 and 720 days, whereas for STEMI patients, 12-month DAPT appeared to be better at 720 days. NSTEMI patients seemed to have less favourable long-term outcomes than STEMI patients in this subanalysis. Further adequately powered randomised trials are needed to confirm the findings.
Pilot study of the efficacy of treatment of urticaria by using two traditional Vietnamese herbs administered systemically
Authors: Bach Thị Như Quỳnh , Pham Van Thức , Nguyen Thị Thuỳ Dung , Nguyen Thị Hien , Floch Katell , Nguyen Thị Hồng Liên , Carre Jean-Luc
Published: July 2022

Among the many plants used in traditional medicine in many countries, Averrhoa carambola L. and lonicera japonica Thunb are regularly the subjects of publications describing the pharmacological effects of their extracts. Lonicera japonica Thunb is particularly studied.
Alkoss – A találékonyság pszichológiája! Kreativitás mint képességvizsgálat a Tóth-féle kreativitás becslő skála segítségével a Nemzeti Közszolgálati Egyetem hallgatóinak körében
Authors: Dominek Dalma Lilla , Ceglédi Szabolcs
Published: August 2022

A kreativitás vizsgálata egyre aktuálisabbá válik a mai információkkal teli világban, így az oktatás területén is. A kutatásunk fő célja a Nemzeti Közszolgálati Egyetem hallgatóinak (N=132) kreativitásszint-vizsgálata a kreativitás pedagógiai és oktatás-módszertani megközelítésének értelmezési keretein belül. Kutatásunk során megvizsgáltuk, hogy melyek azok a tényezők, amelyek hatást gyakorolnak az egyén kreativitásszintjére. Ennek feltárására a képzési típusokból és nemek szerinti eltérésekből fakadó különbségeket kerestük, jelen kutatás nem terjed ki az életkori eltérések bemutatására. Tóth és Király (2006) korai mérései nem találtak jelentős különbséget a vizsgált férfiak és nők körében, így azt feltételezzük, hogy ez esetünkben sem lesz másként, ugyanakkor képzési típusok terén korábbi kutatási eredmények hiányában nem alkothatunk olyan előzetes feltevéseket, amelyeket az említett adatokkal alátámaszthatnánk, mégis szükségszerű, hogy megvizsgáljuk, adódnak-e esetleges differenciák levelezős és nappali tagozatos hallgatók között. Azonban ehhez elengedhetetlen a kreativitás pszichológiai vetületének feltárása is. Így jelen tanulmány a kreativitás pszichológiai hátterét szintén szemlélteti, melynek keretében egy kérdőíves kutatás eredményeit is bemutatjuk. Annak érdekében azonban, hogy a téma pedagógiai irányvonalára is reflektáljunk, röviden írunk a téma pedagógiai hátteréről is.