bluuebunny/crossref_metadata_2025 huggingface dataset:
Estimating mixture hybrid Weibull distribution parameters for wind energy application using Bayesian approach
Authors: Guenoupkati Agbassou , Salami Adekunlé Akim , Bokovi Yao , Koussetou Piléki Xavier , Ouedraogo Seydou
Published: August 2023

The Weibull distribution function is essential for planning and designing wind-farm implementation projects and wind-resource assessments. However, the Weibull distribution is limited for those areas with high frequencies of calm winds. One solution is to use the hybrid Weibull distribution. In fact, when the wind speed data present heterogeneous structures, it makes sense to group them into classes that describe the different wind regimes. However, the single use of the Weibull distribution presents fitting errors that should be minimized. In this context, mixture distributions represent an appropriate alternative for modelling wind-speed data. This approach was used to combine the distributions associated with different wind-speed classes by weighting the contribution of each of them. This study proposes an approach based on mixtures of Weibull distributions for modelling wind-speed data in the West Africa region. The study focused on mixture Weibull (WW-BAY) and mixture hybrid Weibull (WWH-BAY) distributions using Bayes' theorem to characterize the wind speed distribution over twelve years of recorded data at the Abuja, Accra, Cotonou, Lome, and Tambacounda sites in West Africa. The parameters of the models were computed using the expectation-maximization (E-M) algorithm. The parameters of the models were estimated using the expectation-maximization (E-M) algorithm. The initial values were provided by the Levenberg-Marquardt algorithm. The results obtained from the proposed models were compared with those from the classical Weibull distribution whose parameters are estimated by some numerical method such as the energy pattern factor, maximum likelihood, and the empirical Justus methods based on statistical criteria. It is found that the WWH-BAY model gives the best prediction of power density at the Cotonou and Lome sites, with relative percentage error values of 0.00351 and 0.01084. The energy pattern factor method presents the lowest errors at the Abuja site with a relative percentage error value of -0.54752, Accra with -0.55774, and WW-BAY performs well for the Tambacounda site with 0.19232. It is recommended that these models are useful for wind energy applications in the West African region.
Analisis Short Circuit dan Mitigasi Bahaya Arc Flash pada Switchgear 20 kV dan PMCC (Power Motor Control Center) 0,42 kV pada PT. Unilever Oleochemical Indonesia
Authors: Syafrudin Khafis Aji , Darmanto Nugroho Agus , Denis Denis
Published: August 2023

PT. Unilever Oleochemical Indonesia merupakan salah satu perusahaan oleokimia terbesar di dunia yang menggunakan 2 sumber tenaga listrik untuk menjalankan proses produksi, yaitu Combined Heat Power Gas Turbin Generator sebagai sumber energi dalam kondisi normal dan feeder PLN sebagai backup energi. Sistem ketenagalistrikan yang aman dan handal menjadi hal yang sangat penting dalam industri sehingga diperlukan sistem proteksi yang menyeluruh untuk menjamin keamanan pasokan listrik. Tugas akhir ini membahas tentang analisis short circuit dan mitigasi bahaya arc flash pada switchgear 20 kV dan PMCC (Power Motor Control Center) 0,42 kV pada PT. Unilever Oleochemical Indonesia. Analisis short circuit serta analisis dan mitigasi bahaya arc flash dilakukan dengan menggunakan software ETAP 16.0.0 yang divalidasi dengan perhitungan manual short circuit berdasarkan standar IEC 60909-0 2001 dan perhitungan manual arc flash berdasarkan standar IEEE 1584-2002. Hasil dari analisis short circuit digunakan untuk melakukan analisis arc flash. Hasil akhir dari analisis arc flash berupa rekomendasi PPE/APD yang harus digunakan pekerja ketika beraktivitas di lingkungan bertegangan berdasarkan standar NFPA 70E 2015 dan label peringatan bahaya arc flash.
Perancangan Alat Estimasi Indeks Massa Tubuh untuk Pengguna Berkebutuhan Khusus
Authors: Mawardi Kholid , Riyadi Munawar Agus , Christyono Yuli
Published: August 2023

Dengan akal dan pikiran yang di karuniakan oleh Tuhan manusia berlomba-lomba untuk mengembangkan teknologi. Teknologi  berkembang dengan  sangat pesat dari waktu ke waktu salah satunya perkembangan teknologi dibidang kesehatan. Alat Estimasi Indeks Massa Tubuh(IMT) untuk Pengguna Berkebutuhan Khusus. Dengan memanfaatkan teknologi yang ada yaitu gelombang ultrasonik pada sensor HC-SR04. sensor HC-SR04 mengeluarkan suara dengan frekuensi yaitu 20 kHz yang tergolong dalam gelombang ultrasonik dapat merambat melalui medium berupa cair,medium  padat, dan lewat medium gas, serta dapat dipantulakan pada permukaan cair dan padat. gelombang ultrasonik dapat digunakan sebagai metode pengukuran tinggi badan pada Alat Estimasi Indeks Massa Tubuh untuk Pengguna Berkebutuhan Khusus dengan memanfaatkan delay gelombang pantulan dan gelombang datang. Untuk melakukan pengukaran tinggi lutut, digunakan sensor ultrasonik HC-SR04 dan menggunakan Arduino Uno sebagai kontroler. Setelah tinggi lutut diperoleh dan telah menginput jenis kelamin  selanjutnya  sistem akan menghitung dengan persamaan Fatmah untuk memperoleh data tinggi badan, data berat badan juga diperlukan untuk meghitung indeks massa tubuh. Untuk memperoleh data berat badan digunakan sensor berat load cell dimana sensor berat load cell merupakan sensor untuk berat yang dapat digunakan untuk timbangan. Ketika semua data yang dibutuhkan telah diperoleh, data kemudian akan dikirim ke database melalui komunikasi USB serial untuk dilakukan perhitungan IMT.
PERANCANGAN PENGATURAN KECEPATAN MOTOR DC PADA OTOMASI SABLON KAOS DENGAN METODE PULSE WIDTH MODULATION (PWM)
Authors: Wibowo Bagus Catur , Triwiyatno Aris , Sudjadi Sudjadi
Published: August 2023

Otomasi sablon kaos adalah sebuah perancangan yang mengubah sistem penyablonan kaos menjadi otomatis menggunakan penggerak berupa motor dan silinder aktuator. Otomasi sablon kaos terdiri dari sistem pemindah kaos, sistem pemberian tinta sablon, sistem penyablonan dan sistem pengeringan. Proses memindahkan kaos menggunakan konveyor dengan penggerak motor listrik, pemberian tinta dilakukan dengan pompa tinta, proses penyablonan menggunakan motor listrik yang terhubung dengan leadscrew untuk mengubah putaran motor menjadi gerakan linier, proses pengeringan dilakukan dengan lampu halogen sebagai pemanas.  Proses penyablonan pada desain ukuran kecil dan besar memiliki perbedaan dalam kecepatan penyablonan, semakin besar ukuran desain semakin pelan kecepatan penyablonan yang dibutuhkan untuk hasil yang terbaik. Pada tugas akhir ini akan dirancang spesifikasi kebutuhan motor penggerak konveyor, spesifikasi pompa tinta, spesifikasi motor penyablonan dan spesifikasi lampu halogen. Perancangan kontrol kecepatan motor penyablonan dilakukan pada motor DC 37GB31ZY yang memiliki torsi 1,098 Nm dengan kecepatan maksimal 140 rpm. Kontrol kecepatan menggunakan metode Pulse Width Modulation yang dibangkitkan dari IC NE555 berdasarkan variasi perubahan resistansi potensiometer sebagai kendali duty cycle. Nilai duty cycle minimal yang dapat dihasilkan bernilai 3,26% dan nilai maksimal yang dihasilkan mencapai 99,74% pada tegangan masukan 12,75 V. Kecepatan penyablonan maksimal yang dihasilkan dengan kontrol kecepatan mencapai 14,7 mm/s.
Value, Virtue, and Vivienne Westwood: On the Philosophical Importance of Fashion
Authors: Olive Colette
Published: August 2023

In the aforementioned quote, Vivienne Westwood sketches a role for fashion that elevates it from the prosaic to the status of art, as something important, life-enhancing, and worthy of pursuit. Here, a philosophical treatment of Westwood’s vision of fashion that does justice to the artistic and life-enhancing value that fashion can realise is offered, using an emergent theory in contemporary analytic aesthetics. The virtue theory of art delineates the intrinsic worth of art in terms of the opportunities it provides for us to exercise and cultivate virtues such as courage, self-expression, imagination, wit, or authenticity. Our engagement with art can subsequently be genuinely life-enhancing in lieu of the constitutive role the virtues play in living well. The present study takes Westwood’s claims as a jumping-off point, considering how they speak not just to her own designs but to our relationship with our clothes more broadly. Fashion is defended as a practice that performs this function in analogous ways to other genres of art and thus has clear artistic value as well as enables us to live well. Given this potential, just as Westwood claimed, there are reasons to perform the practice well because it has importance for the ways in which it can realise artistic value and aid us in living well.
Believing for Practical Reasons in Plato’s
Gorgias
Authors: Blackson Thomas A.
Published: August 2023

In Plato’s Gorgias, Socrates says to Callicles that “your love of the people, existing in your soul, stands against me, but if we closely examine these same matters often and in a better way, you will be persuaded” (513c7–d1). I argue for an interpretation that explains how Socrates understands Callicles’s love of the people to stand against him and why he believes examination often and in a better way will persuade Callicles.
Aristotle as an Astronomer? Sosigenes’ Account of
Metaphysics
Λ.8
Authors: Golitsis Pantelis
Published: August 2023

I have argued elsewhere that the idea that Aristotle aspired to improve the theories of the planetary motions of Eudoxus and Callippus by adding the ‘counteracting’ spheres (ἀνελίττουσαι) first emerged with the Peripatetic exegete Sosigenes in the second century CE. This paper supplements that argument by contrasting two major lines of interpretation of the astronomical system set out in Metaphysics Λ.8: Adrastus of Aphrodisias’ widely ahistorical account, and Sosigenes’ attempt to save Aristotle against later developments of astronomical science.
Photosynthetic apparatus variability of the rigid hornwort (Ceratophyllum demersum L.) from the Saksagan River influenced by the mine activity
Authors: Marenkov O. M. , Alexeyeva A. A. , Khromykh N. O. , Holub I. V. , Drehval I. V.
Published: August 2023

Aquatic ecosystems are the final absorbers of various pollutants, so require complex monitoring to control their condition. Macrophytes and other aquatic plants serve as reliable indicators of the hydro ecosystems ecological state, as they provide an integral assessment of the aquatic environment in time and space. Changes in chlorophyll a and chlorophyll b content and ratio in the rigid hornwort (Ceratophyllum demersum L.) leaves depending on the water hydro chemical parameters of Saksagan River in the zones of influence of "Ternivska" and "Oktyabrska" mines (Kryvyi Rih city) were studied. The purpose of the work was to find out the features of C. demersum photosynthetic apparatus reorganization as plants adaptive reaction to the technogenic transformation of river ecosystem. The water mineralization changes in the range of 1.2–2.9 g/L and fluctuations in the nitrates and nitrites content in the Saksagan River different sections were established. Both an increase and a decrease in the content of chlorophyll both forms in C. demersum leaves were detected, but more significant changes were related to chlorophyll b content. The photosynthetic pigments total content in plant leaves was the highest in the most mineralized areas (points of return water discharge and 500 m below of "Ternivska" mine), and it was the lowest due to sharp water mineralization increasing (500 m below the return water discharge of "Oktyabrska" mine). Significant variability in the photosynthetic pigments content and ratio indicates flexible regulation of their synthesis in C. demersum leaves to maintain the efficiency of the photosynthetic apparatus under conditions of water pollution. The revealed regularities indicate the active protection of the photosynthetic process in the C. demersum leaves, which is an important prerequisite for the plant’s survival in adverse conditions and the preservation of the structure and productivity of the water ecosystem of the Saksagan River.
The Specifics of the Economic Tradition of Russian Society: from Byzantine Origins to Postindustrialism and Postmodernism
Authors: Eldin Mikhail A. , Raslova Anastasia A.
Published: August 2023

Introduction. In the history of Russian public thought, the issues of human economic activity have been considered from time immemorial through the prism of ethics of justice. Many things have been borrowed from the practice of Byzantine religious morality of economic taxonomism. In the Byzantine patristic paradigm, economy-house-building was analyzed as a field for spiritual growth in the field of Orthodox obedience. Wealth and success were not condemned, but evaluated as a challenge to the test. At the same time, from John Chrysostom to the thinkers of Moscow Russia, the theme of economic activity was presented as serving the highest social ideals of spiritual service. In the imperial period, the problems of economic life were analyzed from the standpoint of service to the state from S. N. Bulgakov to P. B. Struve. The Soviet model of state regulation turned out to be unique and did not reproduce much the previous experience of Rus – Russia in terms of the complexity of the national economy.

Material and Methods. An integrative approach combined with historical-methodological and philosophical-historical analysis is considered as a theoretical and methodological research strategy. The solution of research tasks was provided by a complex of complementary theoretical (analysis of scientific, historical literature, journalistic research on the studied problem, comparative analysis of texts, comparison, generalization) and empirical (study and generalization of normative legal documents in the concepts of caesarepapism and secularism) methods.

Results. The considered model of postmodernism in terms of its understanding in the Russian economic tradition and the specifics of the national economic structure in the realities of Russian history testifies to the secondary, borrowed nature of postmodern concepts.

Discussion and Conclusion. The expected effect of the actual understanding of the processes can be a properly constructed model of state-public relations, which can appear only with a balanced factor of diverse interests of actors of modern state-economic policy of Russia.
El Papel del Colegio de Trabajadores Sociales de Costa Rica durante la Covid-19
Authors: Monge Campos Ana
Published: August 2023

Resumen

Introducción: Las condiciones laborales se agudizaron durante la pandemia, el desempleo de la profesión, la disminución de las posibilidades de contratación por parte del Estado, la sobreoferta de personas graduadas y la redefinición de algunos de los puestos que eran desempeñados por profesionales en trabajo social.

Objetivo: Aportar a las organizaciones de profesionales la experiencia del COLTRAS durante la pandemia, y cómo se abocó al apoyo y solidaridad con las personas agremiadas, en quienes repercutió la afectación emocional, económica y social producto de la pandemia misma y la participación en la ejecución de acciones emanadas por la Comisión Nacional de Emergencias y por el Ministerio de Salud.

Método y técnica: El método utilizado fue sistematización de las acciones, la construcción de informes de Presidencia y Planes de Trabajo de las comisiones. Entre las técnicas utilizadas fueron las sesiones virtuales, entrevistas con las colegas coordinadoras de programas de primera línea de los sectores de la salud, educación, municipales y organizaciones locales, entre otras. La integración y colectivización de experiencias fue realizado paulatinamente por parte de la secretaria de la junta con apoyo del equipo administrativo del COLTRAS.

Resultados: Se visibilizó aún más las desigualdades e inequidades en la población y se incrementaron las vulnerabilidades en los sectores de atención de trabajo social. La virtualidad permitió mayor integración de las filiales a nivel regional y sectorial y mayor visualización de la profesión.

Conclusiones: Se fortaleció la investigación, capacitación, sistematización y la correspondiente divulgación de experiencias, lo que robusteció el servicio profesional.
Urban adaptation to climate change and resident awareness. A Polish perspective
Authors: Rajca Joanna , Olczak Barbara , Wilkosz-Mamcarczyk Magdalena
Published: August 2023

The development of urban areas over the last several decades has significantly contributed to climate change. The modern approach to spatial planning and land management responds to the adaptation of cities to changing climate conditions and the need for a liveable environment. The land use of new green spaces and the upgrading of the existing ones should include adaptation to the present and future climate conditions. Cities can adjust to climate change in many different ways. Over the years, the expansion of urban areas has generated a trend towards higher average temperatures than in rural areas, especially in densely populated urban centres with scarce vegetation where temperatures tend to be higher. City growth is detrimental to the natural environment and water circulation. Insufficient vegetation contributes to high air temperature in cities and urban heat islands. In addition, poor water retention and water infrastructure exacerbate urban droughts and floods. Therefore, efforts should be interdisciplinary and multi-faceted to achieve the best results. Adaptation to climate change faces in Poland multiple and diversified barriers. Hence the question: what is happening at the social level? Are residents of cities conscious of the problem, and do they know how to respond to it? What are the barriers concerning climate change? The paper investigates the public awareness of climate change in Poland. The results demonstrate that there is insufficient awareness of climate change in Polish society and a broad remedial measures are needed.
A Uniform Acquisitional Path for Linguistic Recursion
Authors: Mao Tiaoyuan , Chang Xiangyu
Published: August 2023

While children’s acquisition of recursion has drawn extensive attention in the field, there is less research offering proper evidence for the uniform developmental path of linguistic recursion. To address this issue cross-linguistically, this study examines how 84 Mandarin-speaking children aged between three and six comprehend two to four-level DeP recursion through a pointing task. The results reveal that two and three-level DeP recursion is successfully generated by four-year-old children first, and then five-year-old children fully master four-level DeP recursion. The findings are consistent with the developmental route-map of Japanese children’s acquisition of recursive possessives. Meanwhile, the analysis shows that the biological maturation of the recursive mechanism and the enhancement of computational efficiency of the linguistic mechanism mainly account for the step-by-step development.
Hydrothermally grown optically enhanced CdS-GO nanocomposites
Authors: Kaundal Jyoti Bala , Tiwari Rajendra Kumar , Goswami Yogesh Chandra
Published: August 2023

Nanocomposites based on graphene oxide have shown significant potential in various applications, including solar devices. In this paper, hydrothermally synthesized cadmium sulfide (CdS)-embedded graphene oxide (GO–CdS) nanocomposites were reported. The resulting powder was black and was filtered and washed with distilled water. The samples were then characterized by X-ray diffraction, Fourier transform infrared (FTIR) spectroscopy, optical transmission and photoluminescence studies. The samples demonstrated a polycrystalline phase with a rutile structure and high luminescence peaks. As the amount of cadmium sulfide in the graphene oxide increased, the particle size of the nanocomposites also increased. FTIR analysis confirmed the formation of GO–CdS nanocomposites. Furthermore, the samples exhibited excellent photoluminescence, which made these composites highly suitable for optoelectronic applications.
ORFanID Web-based Search Engine to IdentifyOrphan and Taxonomically Restricted Genes v1
Authors: Galbadage Thushara , Gunasekera Vinodh , Tundrea Emanuel , S. Gunasekera Richard
Published: August 2023

ORFanID is a web-based software engine designed to identify ORFan genes from genomes of interest; from a given list of DNA or protein sequences within the NCBI databases. The selection of the taxonomy level of interest can define the scope of the search for orphan genes. Detectable homologous sequences are found by the software for candidate genes in the NCBI databases. Based on these findings, the ORFanID engine identifies and depicts orphan genes. Results may be viewed and analyzed graphically for scientific research and inquiry. As the enigma of orphan genes unravels, we believe ORFanID will provide critical insights into the origin, function, and prevalence of ORFan genes in genomes.
U54 SCENT Histology H&E Staining v1
Authors: McCall Shannon
Published: August 2023

To provide a standardized method of running, cleaning, refilling, and verifying quality of the automatic H&E stainer. Every morning before running slides for projects, a quality control slide containing brain, kidney, liver, and pancreas tissue is run, reviewed, and deemed acceptable by a histotechnician, who documents this review.
Free floating immunofluorescent staining protocol on mouse brain sections v2
Authors: Sagredo Giselle
Published: August 2023

This protocol describes our free-floating immunofluorescence staining protocol used to investigate the fate and pathologyof human iPSC-derived cells grafted in the mouse brain. This protocol allows for the post-mortem visualisation and analysis of the morphology and pathological inclusions of the transplanted human iPSC-derived cells carrying different PD-related mutations in different regions within mouse brain tissue sections.
U54 SCENTOlink® Target 96 v1
Authors: not provided andrew.nixon
Published: August 2023

This protocol outlines the sample preparation and running of the Olink 96 panel
U54 SCENT T/NK Immunosenescence Profiling Flow Cytometry Panel v1
Authors: R Healy Zachary
Published: August 2023

This protocol describes the T/NK Immunosenescence Profiling Flow Cytometry Panel
My earth-EVAL pilot v1
Authors: Teran-Escobar Claudia
Published: August 2023

Background. Certain activities embedded in academic culture (international conferences, field missions) are an important source of greenhouse. Although some institutions and members of the scientific community have started to propose ways to reduce the impact of Academia, collective efforts should be pursued. Serious games have been used in the past to promote ecological transition. Nevertheless, to our knowledge, the deployed evaluations have only measured the changes on knowledge and not on behaviour. The main objectives of this study are to 1) Evaluate the feasibility of two interventions and, 2) Evaluate the fidelity of the interventions provided to the experimental and control groups.Methods. People employed by a French public or private research organisation (N=30) will be recruited and randomised to one of the two arms. The experimental arm consists in a 1-hour group discussion for raising awareness about climate change, carrying out a carbon footprint assessment and participating to a serious game called “My earth in 180 minutes.” The control arm consists in a 1-hour group discussion for raising awareness about climate change, carrying out a carbon footprint assessment. During two-time measurements spread out over one month, participants will fill up online surveys about their behaviours, psychological constructs related to behaviour change, sociodemographic and institutional information. For session of intervention, the facilitators will fill up information about task completion, perceived complexity of the tasks, percentage of completion of online questionnaires, duration of each session and perceived responsiveness of participants. Descriptive statistics will be done to analyse percentages and averages of the different outcomes.Discussion. My-earth EVAL pilot study is a 1-month and a half pilot randomised controlled trial aiming to evaluate the feasibility and the fidelity of a 24-month randomised controlled trial aiming to change academic practices such as professional mobility by air, daily commuting and digital and material purchases.
Directing Paths Into Adulthood: Newly Arrived Students and the Intersection of Education and Migration Policy
Authors: Rydell Maria , Nyström Sofia , Dahlstedt Magnus
Published: August 2023

This article is centred on the tendency to align education for newly arrived students with migration policy. Drawing on an in-depth analysis of interviews with four adult migrant students, we aim to investigate how the participants’ experiences of studying and how they imagine their future intersect with their immigration status. The interviews were conducted when they were first studying a language introduction programme, and then three years later. We focus on the participants’ narratives about transitions within the education system and later into the labour market. Using Sara Ahmed’s approach to the orientation of subjects in time and space, the analysis shows that all students expressed a desire to “be in line,” meaning finishing their studies and finding employment. Students with temporary and conditional residence permits were directed towards specific vocational tracks and sectors of the labour market. Migrant students are a heterogenous group and, based on the findings presented, we argue that immigration status constitutes a crucial part of this heterogeneity, influencing how students imagine their future in a new society.
Prevalência e fatores associados aos óbitos pela COVID-19: estudo transversal
Authors: Carvalho Mariane Cardoso , Melo Rosana Alves de , Fernandes Flávia Emília Cavalcante Valença , Góis Amanda Regina da Silva , Mattos Rachel Mola de , Teles Roxana Braga de Andrade
Published: August 2023

Objetivo: avaliar a prevalência e os fatores associados aos óbitos pela COVID-19 em Pernambuco. Método: estudo transversal com a utilização das bases dos dados referente ao acompanhamento das notificações por COVID-19 em Pernambuco. Resultados:  Prevalência do sexo masculino (54,1%), não idoso (53,0%) com alguma comorbidade (55,6%). Prevaleceram os sintomas gripais (82,5%) e dispneia (80,2%). Entre os fatores associados à mortalidade, prevaleceram os idosos (OR 3,57; p-valor=0,000), a presença de doenças hepáticas (OR 4,81; p-valor=0,000), doenças renais (OR 2,94; p-valor=0,000) e sobrepeso ou obesidade (OR 2,38; p-valor=0,000), sintomas como dispneia (OR 1,31; p-valor=0,000) e saturação de O2 <95% (OR 1,42; p=valor=0,000). Conclusão: A prevalência foi de homens, não idosos e com comorbidades. Os principais fatores associados aos óbitos foram a presença de comorbidades e ser idoso.
The role of lenvatinib in the era of immunotherapy of hepatocellular carcinoma
Authors: Lee Matthew Man Pok , Chan Landon Long , Chan Stephen Lam
Published: August 2023

Hepatocellular carcinoma (HCC) frequently presents as advanced stage with poor prognosis and high mortality. Systemic treatment is the treatment of choice for advanced disease. In 2007, the first multi-kinase inhibitor (MKI) sorafenib was approved and shown to modestly prolong overall survival (OS). The progress of systemic therapy has been slow afterwards until 2018 when lenvatinib, another MKI, was shown to be non-inferior to sorafenib on median OS as the first-line therapy for HCC. Since then, remarkable progress has been achieved on the treatment of advanced HCC, including the development of second-line targeted treatment, including regorafenib, cabozantinib and ramucirumab from 2017 to 2019. A growing focus has been placed on immune checkpoint inhibitors (ICIs) targeting programmed cell death-1 (PD-1), its ligand PD-L1, and cytotoxic T-lymphocyte-associated protein 4. These ICIs have proven their potency in treating HCC as both initial and subsequent line of therapy. At present, both regimens of atezolizumab combined with bevacizumab, as well as the combination of tremelimumab and durvalumab, are recommended as the first-line treatments based on positive phase III clinical trials. With the advancement of ICIs, it is anticipated that the role of MKIs in the treatment of HCC will evolve. In this article, lenvatinib, one of the most commonly used MKIs in HCC, is chosen to be reviewed.
SimTank – um simulador de nível de líquido em tanques
Authors: Trigueiro Tancredo Caciano , Lira Valnyr Vasconcelos
Published: August 2023

Sistemas de controle de nível de líquidos em tanques são amplamente utilizados em processos industriais. Diversas configurações podem ser encontradas na prática, por exemplo: sistemas com apenas um tanque (onde um determinado material é acumulado para ser processado) e sistemas com tanques acoplados (em série ou em cascata, onde o material de um tanque é misturado com o material presente em outro tanque). Independentemente do sistema, a dinâmica do nível de líquido nos tanques é obtida através do balanço de massa do sistema, ou seja, o nível de líquido no tanque varia de acordo com a diferença entre a massa que entra e a massa que sai do tanque. Como a construção de um sistema didático de tanques (planta piloto), apesar de ser relativamente simples, pode ser economicamente inviável (já que são necessários vários kits, principalmente se desejarmos que diversos usuários o utilizem ao mesmo tempo), uma opção é utilizar um software simulador. No entanto, para que seja mantido o aspecto visual, que é bastante importante para o aprendiz, o simulador deve apresentar não só a dinâmica do nível de líquido nos tanques, mas também uma animação do sistema, sendo esses os principais objetivos desta pesquisa. Assim, neste artigo é apresentado um simulador, desenvolvido no ambiente MATLAB, cujos resultados de simulação possuem tais características.
Desafios da comunicação pública em uma instituição federal de ensino
Authors: Abiahy Ana Carolina De Araújo
Published: August 2023

O artigo analisa os desafios da Comunicação Pública em uma instituição da Rede Federal de Educação Profissional, Científica e Tecnológica através de resultados alcançados em pesquisas realizadas nos últimos cinco anos. Foram realizadas entrevistas com gestores, análise sobre as ferramentas mais utilizadas pelos canais
oficiais de comunicação, com enfoque mais específico no uso das mídias digitais. Os conceitos de Comunicação Pública, em sua intersecção com a Comunicação Estratégica e Organizacional, balizam teoricamente esse estudo. Reflexões sobre novas práticas de comunicação com vistas ao alcance das políticas públicas e à democratização dos serviços são desenvolvidas nesse texto. Autores como Sodré, Primo, Recuero, Duarte e Brandão são suportes teóricos utilizados.
Análise experimental do efeito de diversas configurações de "inset feed" na alimentação de antenas planares dos tipos retangular, circular e triangular
Authors: Silva Jefferson Costa e
Published: August 2023

Este artigo trata da análise experimental de antenas planares, com geometria do patch dos tipos retangular, circular e triangular, com alimentação por linha de microfita e técnica de casamento de impedância através de reentrâncias (inset feed) assimétricas no patch radiante, de modo a se verificar a resposta em frequência dessas antenas para diversas configurações de assimetria. A partir desse objetivo, foram realizadas diversas medições para a verificação do efeito desse tipo de alimentação no casamento de impedância das antenas simuladas.
The influence of obesity on the risk of development of selected gastrointestinal cancers
Authors: Marcinkiewicz Anita , Borowska-Waniak Karolina , Łukaszczyk Aneta , Ochotnicka Aleksandra , Opala Anna , Borowska Maja , Skorupińska Kinga , Michalik Dominik
Published: August 2023

Purpose of the study: The subject of consideration is the influence of obesity on gastrointestinal cancers. Considerations were focused on discussing the connection between obesity and the risk of cancer of particular organs of the gastrointestinal tract. The aim of the work is to analyze this phenomenon and to show the connection between these two issues.

Methodology: The article was prepared with the use the critical literature review method. Appropriate materials focused on the subject of consideration were searched, among others, in PubMed and specialized literature.

Main conclusions: The analyzes of available materials show that obesity significantly affects the occurrence of gastrointestinal cancers, and also affects the treatment and prognosis of cancer patients. It predisposes not only to gastrointestinal cancers, which are the subject of this article, but also to other cancers, which is worth emphasizing.

Applied studies: The article shows the broad influence of obesity on particular gastrointestinal cancers. The content contained in the article can be useful for doctors to systematize knowledge, but also for patients to make them aware and motivate them to change and a healthier lifestyle.

Originality of research: The report presents medical knowledge in an accessible way, making it easier to assimilate. It allows to understand the problem of obesity and its impact on the incidence of gastrointestinal cancers. It may also inspire further research on this issu.
Selected components of body mass composition and blood pressure in a group of students of the University of Rzeszów
Authors: Kawa Grzegorz , Matłosz Piotr , Barańska Katarzyna
Published: August 2023

Purpose of the study: The aim of the study was to investigate the association between selected components of body mass composition and blood pressure in a group of students at the University of Rzeszów.

Methodology: The article was prepared using the method of critical literature review and statistical study of selected components of body mass composition and blood pressure in a group of students at the University of Rzeszów.

Main findings: The study showed that the prevalence of overweight and obesity based on BMI and FAT% in the study group of students was low. BMI values indicated that only 27 subjects, representing 19.57% of the study group, were overweight. The mean arterial pressure in the women was within the normal range, indicating that there were no significant problems of hypertensive disease in this group. on the other hand, among the male representatives, the mean arterial pressure was above the normal values. On the basis of the study, it can be seen that there is a correlation in the prevalence of overweight among adults in rural areas, where 17 people (12.32% of all subjects) were overweight. The present study showed a trend in the prevalence of high blood pressure among men from rural areas (135/76 mmHg) and from urban areas with less than 20,000 inhabitants (137/75 mmHg). Excess body weight and percentage of body fat showed no association with the prevalence of hypertension in the study group.

Application of the study: The presented article refers to the selected components of body mass composition and blood pressure in a group of students at the University of Rzeszów. The tool used will make it possible to analyse the problem and to find probably non-positive changes affecting their health. The content can be used by PhD students to make people aware of this existing problem.

Originality/Novelty of the study: Selected components of body mass composition versus blood pressure is a new issue that is gaining popularity over time. It is noteworthy that although it is known, but few people know about the exact consequences of an abnormal component on blood pressure and health. This article may encourage further research on this topic and behavioural change among people.
A Simple, Stable, and Highly Sensitive Spectrophotometric Method for the Determination of Arsenic(III) from Different Biological Media in the Presence of Nanosilica-Cysteine Composite
Authors: ALNASRA Omar , KHALİLİ Fawwaz
Published: August 2023

This paper describes a selective and fairly stable colorimetric approach to determine trace amounts of arsenic conjugated with nanosilica-cysteine composite in various aqueous and biological samples in milligram per liter (mg/L) using Leucocrystal Violet (LCV) as a chromogenic reagent. Attenuated total reflectance-Fourier-transform infrared (ATR-FTIR) spectroscopy analysis was applied to characterize the composite. Novelty of this method is dealing with the presence of nanosilica which is reflected in the difficulty of obtaining a clear solution. The maximum absorbance is measured and Beer's law shows linearity over the concentration range of (0.75 to 5.00 mg/L) of As(III) at 590 nm. The molar absorptivity, Sandell’s sensitivity, and detection limit of the method were found to be 6.00 × 105 L/mol.cm, 8.55 × 10-2 μg/cm2, and 0.043 mg/L, respectively. The optimum reaction conditions and other analytical parameters were evaluated. Arsenic was successfully detected in a variety of aqueous and biological samples using the proposed method.
"Państwo celów" jako instytucja kultury. Czy krytyka władz podmiotu jest wystarczającą podstawą filozofii kultury?
Authors: Kozłowski Marek
Published: August 2023

Using E. Wolicka book "Consideration on Kant" as an anchoring point, the author investigates the conditions under which 'kingdom of ends' can successfully play a role of institution of culture, i.e. be translated into rules of action and empirical facts in the sphere of every day life and history.
Mecanismos involucrados en la patogénesis de Candidatus Liberibacter asiaticus y bases moleculares de la tolerancia en cítricos
Authors: Pérez-Zarate Luis A. , Villanueva-Jiménez Juan A. , Osorio-Acosta Francisco , García-Pérez Eliseo , Flores-de la Rosa Felipe Roberto , Martínez-Hernández Aída
Published: August 2023

El Huanglongbing (HLB) es una enfermedad considerada como la más destructiva para los cítricos en el mundo, es causada por Candidatus Liberibacter asiaticus (CLas) y diseminada por el vector Diaphorina citri. El HLB ha generado cuantiosas pérdidas económicas en la citricultura mundial. Todas las variedades comerciales de cítricos son susceptibles a esta enfermedad. La naturaleza de CLas como parásito intra celular estricto limitado al floema dificulta el estudio fitopatológico de la enfermedad. Las herramientas “ómicas”, que permiten aplicar análisis comparativos con enfoque masivos, han resultado útiles para describir la interacción entre el agente patogénico y diferentes especies de cítricos, generando conocimiento sobre las bases moleculares de la patogenicidad de CLas y de las respuestas de los hospederos ante la infección. Sin embargo, muchos procesos inmersos en la compleja interacción CLas-cítricos aún no son del todo comprendidos. En la presente revisión se resumen algunos de los principales hallazgos en la última década relacionados con los posibles mecanismos de patogenicidad de CLas a nivel molecular, así como de las respuestas transcripcionales y metabólicas inducidas en cítricos tolerantes o susceptibles, ante la infección. Este conocimiento es necesario para el diseño e implementación de nuevas estrategias para el manejo sustentable de la enfermedad.
Electrocardiographic history of pulmonary arterial hypertension – from diagnosis, through pregnancy, to lung transplantation
Authors: Bula Karolina , Grabka Marek , Mizia-Stec Katarzyna
Published: August 2023

Częstość i charakter zmian w zapisach elektrokardiograficznych u pacjentów z nadciśnieniem płucnym znacząco różnią się zależnie od ciężkości choroby. U pacjentów z łagodnym nadciśnieniem płucnym zapis elektrokardiograficzny (EKG) może być prawidłowy. W niniejszej pracy prezentujemy kolejne zapisy EKG pacjentki z tętniczym nadciśnieniem płucnym (pulmonary arterial hypertension – PAH) w 5-letnim okresie choroby – od postawienia diagnozy aż do przeszczepienia płuc. Opisany przypadek pokazuje różnorodność zmian w zapisach EKG, których nasilenie korelowało ze stanem klinicznym pacjentki. Obserwowane nieprawidłowości w zapisach EKG w przypadku PAH są odwracalne i w prezentowanym przypadku doszło do ich normalizacji po przeszczepieniu płuc.
Awareness of Hospice Care Among Community-Dwelling Elderly Participants
Authors: Liu Jun , Li Jun-fang , Li Xiao-xiao , Wu Yi-ping , Li Shu-rui , Li Li-yang , Zhou Hai-ping
Published: August 2023

Background and Purpose:The main goal of hospice care is to improve the quality of life for people who are at the end-of-life phase. However, investigations on the awareness of hospice care among community-dwelling elderly participants are limited. This work aimed to reveal the awareness status of hospice care and explore the factors influencing the awareness rate among elderly participants.Methods:A questionnaire survey was conducted among individuals aged 60 years and above.Results:A total of 4,969 individuals aged 60 years and above were randomly selected from 48 primary medical institutions in Handan. The awareness rate of hospice care in the baseline survey was 19.3% (n= 959). All included individuals were divided into two groups in accordance with their awareness of hospice care. The awareness of hospice care among participants with low educational level, living alone, and afraid of talking about death was low (p< .05).Implications for Practice:The level of awareness of hospice care among community-dwelling elderly participants is low. The influencing factors included educational level, living status, and fear of talking about death. The community-dwelling elderly participants’ awareness of hospice care must be improved. It is recommended that public medical education and training should be enhanced to improve knowledge and awareness of hospice care among community-dwelling elderly residents with low educational level, living alone, and afraid of talking about death.
Countering Backlash in the Implementation of Bangladesh's Domestic Violence Act
Authors: Sultan Maheen , Mahpara Pragyna
Published: August 2023

Domestic violence rates are high in Bangladesh in spite of laws such as the Nari o Shishu Nirjatan Domon Ain and the DVPPA 2010. According to data from the Bangladesh Bureau of Statistics, almost three in every five women (57.7%) have experienced some form of physical, sexual, or emotional violence in their lifetime. While the formulation and enactment of the DVPPA in 2010 was an achievement for the government, especially the Ministry of Women and Children Affairs that proposed it and the coalition for domestic violence known as the Citizens Initiative against Domestic Violence (CIDV) that championed it, subsequent experience of implementation has been less positive. This policy briefing outlines details, key messages and recommendations from research into the implementation of the DVPPA conducted in 2022 by the BRAC Institute of Governance and Development (BIGD), BRAC University, as part of the “Countering Backlash: Reclaiming Gender Justice” programme hosted at the Institute of Development Studies, funded by the Swedish International Development Cooperation Agency (Sida) programme, and supported by the Swedish Government.
Structural relationship between subsurface oil fields in the North Dezful Embayment: Qaleh Nar, Lower and Upper Balarud Anticlines (central Zagros, Iran)
Authors: RAZAVİ PASH Raana , SERAJ Mohammad , MUKHERJEE Soumyajit , RADMEHR Ahmad
Published: August 2023

How subsurface anticlines (oil fields) link structurally with faults is of great relevance in the exploration and development of oil fields. In this context, we investigate the geometric relation between lower Balarud (LBR), upper Balarud (UBR) and Qaleh Nar (QN) subsurface anticlines that are the main oil fields in the Northern Dezful Embayment, central Zagros. The Asmari (As) and the Bangestan (Bng) reservoirs are studied geophysically using seismic profiles, well data and underground contour maps (UGC). Interpretation of 3500 m deep seismic profiles indicates the geometry of the studied subsurface anticlines differs vertically and horizontally to a significant proportion. The interpreted structures much resemble As and Bng horizons in each anticline. The UBR got overturned on the LBR due to thrusting possibly in the Late Miocene. The LBR, like a rabbit-ear structure, is situated at the northern edge of the QN. The lower and upper Chenareh and LBR and UBR resemble structurally and are separated mutually by a steep (strike-slip) fault. The fault separates the LBR and UBR from the QN. Interaction of different factors: change in overburden pressure, rate of deformation and uplift in the different parts of the subsurface anticlines moved and accumulated Gachsaran Formation

towards both limbs of the anticlines.
Analysis of the Navigation Criteria of Passing Vessel for the Mooring Safety in Adjacent Berth to the Fairway
Authors: Lim Min-Jeong , Cho Ik-Soon
Published: August 2023

The ship wave generated by the passing ship can affect to the nearby berth and moored vessels. This can result in excessive motion of the moored ship and lead to the severing of mooring lines, potentially causing accidents. The aim of this study is to analyze the effect of passing ships navigating through the vicinity of the berth, evaluate the risks posed to the safety of moored ship, and propose safety measures. The OPTIMOOR analysis software was utilized for the assessment, with Berth A in Ulsan Port chosen as the target. The study revealed that the speed of passing ships and the separation distance between vessels significantly influence the motion of moored ships. Considering the high-risk of Berth A due to its proximity to the fairway, proposed navigation criteria for the Ulsan Port's No.1 fairway to ensure mooring safety. It has been determined that passing ships in the vicinity of Berth A should maintain a proper speed less than 8 knots, or navigate at a distance of more than 200 meters away from the dock. This study can contribute to decision-making and the establishment of safety measures in berth and fairway design.
The General Balance in the Six Dimensional of Space-Time
Authors: mousavi seyed kazem
Published: August 2023

On the basis of the findings of this paper, the theories of quantum mechanics and general relativity can be expressed in a comprehensive theory. The events were surveyed length of the time, in the Euclidean six-dimensional space-time (R6=x1+x2+x3+t1+t2+t3). Previous studies have not studied the relationship between the origin of matter's inherent properties, fundamental constants, and quantum mechanics phenomenon with space-time geometry. This theory prediction the with certainty obtained probabilistic results of quantum mechanics. This prediction is on the basis of metric resulting from the Eccentricity of the Ellipse due to the object density, in the length of time. The cause and nature of dark matter and dark energy are the findings of this article.