bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of the degree of tricuspid valve tethering on the early outcome of tricuspid valve repair with the De-Vega technique
Authors: Albatrek Hani , Ramadan Ahmed
Published: January 2023

Background: Functional tricuspid regurgitation (TR) is usually caused by leaflet tethering, and annuloplasty is usually recommended to repair annulus dilatation. This work aimed to evaluate the impact of the degree of the tricuspid valve (TV) tethering on the early outcome of tricuspid valve repair with the De-Vega technique.

Methods: This prospective study included 50 patients with De-Vega tricuspid valve repair. Patients were divided into two groups; Group A (n= 25) included patients with tricuspid valve tethering of 8 mm or less, and Group B (n= 25) included patients with tricuspid valve tethering distance of more than 8 mm.

Results: The mean age of Group A was 46.1 ±3.5 years compared to 49.6 ±7 years in Group B. There were significant differences in postoperative ejection fraction (48.7 ±12.5 vs. 39.1 ±9.4 %, P= 0.003), TV tethering distance (0.6 ±0.2 vs. 1.1 ±0.4 cm, P <0.001), and area (1.1 ±0.5 vs.  2.6 ±0.9 cm2; P<0.001),  and right ventricle fractional area (32.2± 7.9 vs. 25.4 ±9.7 cm2, P= 0.008) in Group A vs. B, respectively. There were no differences in postoperative complications, ICU, and hospital stay between groups.

Conclusion: Residual tricuspid regurgitation after De-Vega annuloplasty could be related to TV tethering distance. Increased TV tethering distance could be associated with reduced postoperative ejection fraction.
Hepatic and gastrointestinal complications after adult cardiac surgery
Authors: Metwally Mohammed , Helal Noha , Hassan Khaled , Ahmed Abdelmoniem , Elgazzar Mohammed
Published: January 2023

Background: Gastrointestinal tract (GIT) complications are associated with increased morbidity and mortality after cardiac surgery. Therefore, The goal of this research was to estimate the frequency of GIT and hepatic complications after cardiac surgery and to determine the risk factors for these complications. Additionally, we studied the effect of these complications on the outcomes of surgery.

Methods: This longitudinal study included 139 consecutive patients who underwent elective cardiac surgery. Patients were grouped according to the GIT and hepatic complications into two groups. Postoperative outcomes were compared between the two groups.  

Results The mean age was 59.43 years, and 106 patients were males (76%). The GIT and hepatic complications rate was 15.8% (n= 22). Hepatic dysfunction occurred in 8.6% of cases, GIT bleeding in 2.9%, paralytic ileus in 2.2%, fulminant hepatic failure in 2.2%, and GIT bleeding combined with paralytic ileus in 0.7%. The overall mortality was 7.2 % (n= 10). The mortality rate in patients who developed GIT and hepatic complications was 45.5% (n= 10 out of 22 patients). There was statistically significantly higher mortality (10 (45.5%) vs. 0; P= 0.001), cardiac arrest (10 (45.5%) vs. 3 (2.6%); P= 0.001), and reoperation rate (5 (22.7%) vs. 6 (5.1%); P= 0.005) among patients with GIT or hepatic complications.

Conclusion: Patients with hepatic and GIT complications could have higher mortality, morbidity, and longer hospital stay than the non-complicated group.
EFEKTIVITAS KOMUNIKASI ANTARPRIBADI ANAK DENGAN ORANG TUA DALAM KELUARGA INTI
Authors: Handayani Nadia , Yuliana Nina
Published: January 2023

Komunikasi merupakan sebuah hal yang sangat penting dalam berinteraksi dengan orang lain, dengan berkomunikasi juga merupakan suatu hal yang tidak bisa terlepaskan bagi seorang manusia. Seseorang akan mengetahui pesan yang dimaksud dari orang lain melalui komunikasi, seperti halnya dalam cakupan keluarga inti. Komunikasi antarpribadi sangat diperlukan dan menjadi faktor penting dalam mengetahui keterbukaan seorang anak serta menumbuhkan perilaku yang baik dalam diri seorang anak. Terkait dengan hal tersebut, maka penulis melakukan penelitian ini dengan komunikasi antarpribadi dikarenakan komunikasi antarpribadi memiliki efektivitas yang lumayan besar dalam berkomunikasi. Tujuan dari penelitian ini adalah untuk mengetahui efektivitas sebuah komunikasi antarpribadi antara anak dengan keluarga inti (ayah, ibu, atau orang tua) dalam menanggapi suatu kejadian, penelitian ini dilakukan dengan metode penelitian kualititatif serta pengumpulan data teknik yang digunakan adalah teknik wawancara mendalam (depth interview) kepada keluarga inti (kedua orang tua, ayah, dan ibu). Lalu dari hasil penelitian tersebut dianalisis dengan ciri-ciri komunikasi antarpribadi yang efektif sesuai dengan apa yang dikemukakan oleh Joseph DeVito, kesimpulan dari hasil penelitian ini menunjukkan bahwa adanya efektivitas komunikasi yang dilakukan dalam menanggapi suatu kejadian melalui komunikasi antarpribadi anak dengan orang tua dalam keluarga inti.Kata kunci: Komunikasi Antarpribadi, Komunikasi, Efektivitas Komunikasi, Keluarga
A Statistic Method for the Prediction of the Succession of Bear and Bull Stock Market
Authors:   Department of Mathematics for Applied Physics of Roberto Caporali, Imola, BO, Italy, Caporali Roberto P. L.
Published: January 2023

In this paper, we define an innovative method for predicting the stochastic behavior of the Bull and Bear periods of the stock market. The direct study of the prediction of possible Bull and Bear markets is a different and new approach about the analysis of stock markets. Our work is based on the collection of 40 years of data from the Italian stock market. The proposed solution is defined using the statistical analysis of the Bear and Bull Stock markets and it includes a criterion for statistically generating the most probable values of the next Bear and Bull markets, as well as especially the lengths of the time intervals corresponding to these market situations. We defined a new system for a stock market price trend prediction, where the trend of the succession of Bull and Bear markets can be described by a probability density function given by a Gaussian distribution. Furthermore, we considered the inverses of the relative time intervals as a measure of the speed with which the phenomenon of the Bear market (or, equivalently, the Bull market) develops in that interval of time and therefore, ultimately, it can represent a first statistical weight of the single percentage variation. Again, the time intervals of the individual Bear and Bull market periods are considered, calculated from 01/01/1973. This is based on the hypothesis that a secondary factor of probability is the temporal distance of the event that has already occurred. In this paper, we conduct a comprehensive evaluation of more frequently used statistical methods for evaluating Stock markets, highlighting the novelty of the described method. Simulation results show the ability of the method to define a statistical prediction of the next Bull and Bear markets.
Sequential Track Fusion in UKF-based Multi-Sensor Networks: A Case of Slip Estimation in Wheeled Mobile Robots
Authors: Zarei Mahboubeh , Chhabra Robin , Mottaghi Mohammadreza
Published: January 2023

Accurate wheel slip estimation facilitates Wheeled Mobile Robots (WMRs) with improved localization and traversability monitoring which are crucial to their autonomy in challenging environments. Although distributed track-level fusion offers better computational efficiency, often sensor-level fusion is adopted in slip estimators.  Extending upon our earlier work, we develop a novel explicit track-to-track fusion algorithm for UKF-based multi-sensor networks that has immediate application to slip ratio estimation in WMRs. The algorithm demonstrates better consistency compared to the existing fusion techniques, since it implements an optimal fusion rule to sequentially combine local tracks. It also saves computational power due to the recursive propagation of cross-covariance matrices based on the statistical linearization technique, instead of performing online optimizations. We prove that this recursion only requires the information of the first and last tracks in a sequence if all local tracks are unbiased. We rigorously study various key properties of the developed fusion algorithm and show its superior level of confidence   when compared to the two prominent fusion methods of sequential and batch covariance intersection. The slip ratio estimation in a six-wheel WMR is considered as a case study, where the steerable wheel sets act as a network of sensors. The proposed slip estimator works based on the rigid body kinematics and readings of purely proprioceptive sensors, i.e., an inertial measurement unit and encoders. The slip estimator's performance is evaluated in a high-fidelity software-in-the-loop simulation environment connecting MATLAB and CM Lab's Vortex Studio software. In a comparison study that considers four rival strategies, we show the superiority of the proposed fusion method offering a balance between consistency, accuracy, and speed in real-time slip estimations.
A Novel Hybrid Quantum-Classical Framework for an In-vehicle Controller Area Network Intrusion Detection
Authors: Salek M Sabbir , Kumar Biswas Pronab , Pollard Jacquan , Hales Jordyn , Shen Zecheng , Dixit Vivek , Chowdhury Mashrur , Khan Sakib Mahmud , Wang Yao
Published: January 2023

In-vehicle controller area network (CAN) is susceptible to various cyberattacks due to its broadcast-based communication nature. An attacker can inject false messages to a vehicle’s CAN via wireless communication, the infotainment system, or the onboard diagnostic port. Thus, an effective intrusion detection system is essential to distinguish authentic CAN messages from false ones. In this study, we developed a hybrid quantum-classical CAN intrusion detection framework using a classical neural network (NN) and a quantum restricted Boltzmann machine (RBM). The classical NN is dedicated to feature extraction from CAN images generated from a vehicle’s CAN bus data. In contrast, the quantum RBM is dedicated to CAN image reconstruction for classification-based intrusion detection. The novelty of the study lies in utilizing the generative ability of the RBM to reconstruct the pixels in a CAN image, a portion of which is dedicated to labeling. Then, that portion of the reconstructed image is used to classify the image as an attack image or a normal image. To evaluate the performance of the hybrid quantum-classical CAN intrusion detection framework, we used a real-world CAN fuzzy attack dataset to create three separate attack datasets, where each dataset represents a unique set of features related to the vehicle. We compared the performance of our hybrid framework to a similar but classical-only framework. Our analyses showed that the hybrid framework performs better in CAN intrusion detection compared to the classical-only framework. For the three datasets considered in this study, the best models in the hybrid framework achieved 97.5%, 97%, and 98.3% intrusion detection accuracies and 94.7%, 93.9%, and 97.2% recall, respectively. In contrast, the best models in the classical-only framework achieved 92.5%, 95%, and 93.3% intrusion detection accuracies and 84.2%, 89.8%, and 88.9% recall, respectively.
A Hybrid Approach for Intrusion Detection in an In-vehicle Controller Area Network using Classical Convolutional Neural Network and Quantum Restricted Boltzmann Machine
Authors: Salek M Sabbir , Kumar Biswas Pronab , Pollard Jacquan , Hales Jordyn , Shen Zecheng , Dixit Vivek , Chowdhury Mashrur , Khan Sakib Mahmud , Wang Yao
Published: January 2023

Controller area network (CAN) is susceptible to various cyberattacks due to its broadcast-based communication nature. In this study, we developed a hybrid approach for CAN intrusion detection using a classical convolutional neural network (CCNN) and a quantum restricted Boltzmann machine (quantum RBM). The CCNN is dedicated for feature extraction from CAN images generated from a vehicle’s CAN bus data, while the quantum RBM is dedicated for CAN image reconstruction for a classification-based intrusion detection. To evaluate the performance of the hybrid approach, we used a real-world CAN fuzzy attack dataset to create three separate attack datasets, where each dataset represents a unique set of features related to the vehicle. We compared the performance of our hybrid approach to a similar but classical-only approach. Our analyses showed that the hybrid approach performs better in CAN intrusion detection compared to the classical-only approach. For the three datasets considered in this study, the best models in the hybrid approach achieved 97.5%, 97%, and 98.3% intrusion detection accuracies, and 94.7%, 93.9%, and 97.2% recall, respectively, whereas the best models in the classical-only approach achieved 86.7%, 95%, and 89.7% intrusion detection accuracies, and 70.7%, 89.8, and 80.6% recall, respectively.
ICT integration by primary school teachers in Tunisia : users profiles and associated factors
Authors: Trabelsi Zied , Naceu Abdelmajid
Published: January 2023

Our study aims to closely analyze the professional uses of ICT by primary school teachers in Tunisia while trying to assess the various factors associated with this use to understand the causes of these differences. Initial theoretical work was necessary to define the concept of usage and present the various factors associated with it in the scientific literature. Then, we conducted a quantitative study with 350 French Language teachers in the primary cycle in Tunisia. The results revealed a weak ICT integration correlated to a set of personal and institutional factors. However, these correlations, by themselves, are not significant enough to explain these low uses. This allows us to explore new approaches in relation to the social dimension of the concept of usage, which considers the teacher as an active social actor who constructs his or her uses in interaction with other actors, hence the importance of considering collective dynamics in the construction of teachers' professional uses of ICT.
UTransBPNet: A General Deep Learning Model for Cuffless Blood Pressure Estimation under Activities
Authors: Zheng Yali , Liu Qing , Hong Jingyuan , Wu Shenghao , Zhang Yuanting , zheng Yali
Published: January 2023

The main challenge in cuffless blood pressure (BP) monitoring lies in its inaccuracy during daily activities. Many previous works either lacked appropriate validation with sufficient intra-individual BP variations, or showed unsatisfactory estimation accuracy under activities. This study introduces a novel deep learning model called UTransBPNet, which aims to improve the estimation accuracy and tracking capability of intra-individual BP changes under activities. UTransBPNet combines the Unet architecture with self- and cross-attention from transformer to estimate BP waveforms, which are then further regressed to systolic (SBP) and diastolic BP (DBP) using additional fully connected layers. The model’s performance was thoroughly evaluated in three distinct datasets: one public dataset (Dataset_MIMIC) and two datasets during activities (Dataset_Drink and Dataset_Exercise). Under subject-independent validation, the model achieved mean absolute differences (MADs) of 4.38 mmHg for SBP and 2.25 mmHg for DBP in Dataset_MIMIC. Additionally, the tracking capability of intra-individual BP variations during activities were also significantly improved. In Dataset_Drink, Pearson's correlation coefficients for SBP and DBP were 0.61±0.17 and 0.62±0.13, respectively. In Dataset_Exercise, the corresponding correlation coefficients were 0.82±0.11 for SBP and 0.72±0.18 for DBP. Furthermore, this study for the first time tested the generalization capability across different activities. The results showed that our model, with small-sized scenario-specific data for finetuning, exhibited a good cross-scenario generalization capability. However, it degraded significantly when there were differences in the BP distributions and variation patterns between the datasets. In conclusion, UTransBPNet shows promise as a deep learning model for accurate cuffless BP estimation and tracking BP changes during activities. 
Optimization of Adaptive Channel Estimation in Over-the-Air Computing Systems
Authors: Evgenidis Nikos , Papanikolaou Vasilis , Diamantoulakis Panagiotis D. , Karagiannidis George K.
Published: January 2023

Over-the-air computing (AirComp) has recently attracted significant attention as an efficient way of data fusion by integrating uncoded communication transmissions with computation thanks to the signal superposition offered by the multiple access channels. However, appropriate processing is required to neutralize the wireless channel effect. Since, internet-of-things (IoT) applications through low-cost devices are the main target of AirComp, perfect channel state information (CSI) availability is not always practical, there exists the need to investigate the effect of imperfect CSI on AirComp. Specifically, we present novel closed-form expressions for tight approximations that can be used to design and evaluate AirComp systems. Moreover, we design a general optimization framework that takes into account both magnitude and phase errors in CSI. Finally, a pilot retransmission policy is designed that offers a trade-off between a cost in resources and gain in the accuracy of the computations. To validate its use, a utility function of the cost of retransmission is introduced, namely, the Retransmission Policy Cost (RPC), which can incorporate the power or throughput cost opposing to the expected gain of the selected policy. Simulation results show the deterioration caused by the imperfect CSI, but, also, highlight the value of the proposed policy under various system conditions.
The Van der Pol Fourier Integral Representation of the Riemann Zeta Function
Authors: kermiche noureddine
Published: January 2023

The Van der Pol Fourier representation of the Riemann Zeta function in the critical strip is evaluated using the Fast Fourier Transform (FFT) algorithm and the Method of Stationary Phase. The Method of Stationary Phase approximation allows us to introduce a new representation for the zeta function. The new representation is used to propose new analytic predictions about non-trivial zeros.
Papilomavírus humano na realidade dos adolescentes brasileiros
Authors: Carvalho Cleziane Reis de , Bezerra Maria Luiza Rêgo
Published: January 2023

Objetivo: analisar a realidade dos adolescentes brasileiros no contexto do papilomavírus humano, bem como dissertar sobre as atuais formas de prevenção encontradas para essa doença e como estas têm sido utilizadas. Método: trata-se de uma revisão integrativa, alicerçada em três bases de dados, LILACS, ScIELO e BDENF, buscando priorizar as publicações mais recentes e mais relevantes para o andamento e fundamentação do estudo. Resultados: foram escolhidos 9 artigos que estão relacionados com o tema para compor o estudo. De maneira geral, o HPV causa o aparecimento de verrugas em diversas regiões, mas principalmente nas regiões genitais. Tem como meio de transmissão o contato de mucosas, devido a isso é considerada uma enfermidade sexualmente transmissível. Conclusão: a grande maioria dos adolescentes não possui conhecimento sobre o que é a doença causada pelo vírus nem o porquê precisa ser vacinado. O estudo demonstrou também que o número de vacinações, de campanhas de conscientização, educação e de conhecimento dos adolescentes, está abaixo do desejado.
Descritores: Papilomavirus Humano; Adolescentes; Vacina.
Testemunhos
Authors: Sassoli David , Martins Guilherme d’Oliveira , Faria Sandra Teixeira de , Colom Jiménez María
Published: January 2023

The statements here presented represent a tribute to David Sassoli and to the European values defended by Sassoli in his discours on the Future of Europe here included.
David Sassoli: Europa, Europa!
Authors: Marcheschi Daniela
Published: January 2023

David Sassoli has best interpreted the great Italian tradition of Europeanism, which had in Giuseppe Mazzini, Vincenzo Gioberti, Altiero Spinelli and Ernesto G. Rossi, the highest and most concrete theoretical and political expressions of the contemporary age. Europe means democracy, therefore freedom, social justice, solidarity among the peoples and within the peoples that make up the European Union. It means building and looking upwards towards peace.
União por meio da democracia
Authors: Guarnieri Ivanor Luiz
Published: January 2023

This article brings an implicit problem: How to unite different peoples and cultures, that are in constant tranformation, around a commom project? The democratic regime is the most approprieate for this task, as it respects diferences and combines it with freedom and justice to promote equal opportunities. On the other hand, the union carried out democratically improves democracy, both favoring each other.
Comparar a Europa. O conceito de literatura europeia como fator de integração política
Authors: Magalhães Gabriel
Published: January 2023

Starting with the last European discourse of David Sassoli, our intention is to reflect on Europe, specifically, on the concept of European literature as a factor of political integration.
De Antero de Quental a Mário Soares: do pensamento à política social na vertigem da democracia portuguesa
Authors: Pereira António dos Santos
Published: January 2023

The future has always been the destiny of men of action. We note the roots of the thought and fiction of the Portuguese socialist leader, Mário Soares, in the references of the political thought of Antero de Quental and the pedagogical of António Sérgio for the economic, social, cultural and mental well-being of the Portuguese people that we make coincide with humanity because western humanism movesus.
O impossível futuro da Europa ou O último europeu 2284 de Miguel Real
Authors: Pais Simon Maria Cristina
Published: January 2023

In 2015, Miguel Real publishes O último europeu 2284 (The Last European 2284), where he conducts, through the tale of an ideal and utopian city, an analysis of a European Union crumbling around all sorts of conflicts. In the current context, does Europe have a future? Is the future of a community compatible with human nature? These are the questions we will be reflecting upon in this article, through the study of this work.
Por uma Europa com vontade de futuro
Authors: Abreu Luís Machado de
Published: January 2023

The Europe of the future, democratic, freedom fighter, promoter of peace and well-being, is a task of all Europeans. The founding fathers of the European project opened up the path that men of good-will like David Sassoli were capable of dynamizing with determination and wisdom. It is important to follow their example and make of the general interest of Europe the common wish of each citizen and each nation.
«Amarás o próximo como a ti mesmo»
Authors: Leão Isabel Ponce de
Published: January 2023

You will love the next as you love yourself was the motto of life and work of David Sassoli, born communicator, who understanded that thought art we fight for any United and democratic Europe who innovates, protects and enlights. Six plastic artist understood his message and translated into different languages prolonging his plea.
Combining humic acid with NPK fertilizer improved growth and yield of chili pepper in dry season
Authors: Ichwan Budiyati , Eliyanti Eliyanti , Irianto Irianto , Zulkarnain Zulkarnain
Published: January 2023

This research aimed to study the effect of humic acid and NPK fertilizer (15:15:15) on growth and yield of red chili, and to obtain the most suitable composition of humic acid and NPK fertilizer which gave the best growth and yield. The study used a randomized block design with five replications. The treatments tested were the composition of humic acid and NPK fertilizer: 100% humic acid; 75% humic acid + 25% NPK; 50% humic acid + 50% NPK; 25% humic acid + 75% NPK; and 100% NPK. Data on plant growth and yield were processed by Analysis of Variance, and means were compared using Fisher’s Least Significant Difference test. In addition, data on plant biochemical and soil chemical parameters were determined compositely by mixing leaves taken from sample plants or soil samples into one homogenous sample. Results showed that there was no significant difference in growth and yield of plants treated with 100% humic acid in comparison with those plants treated with 100% NPK. However, in comparison with 100% humic acid, the application of different ratios of humic acid/NPK increased plant chlorophyll contents by 65% - 82% and total sugar by 28% - 71%. The application of humic acid/NPK increased soil fertility by improving soil pH as well as N, P and K. In the combination of humic acid/NPK, the best growth and yield were obtained with the application of 25% humic acid + 75% NPK fertilizers. Therefore, for the sustainability of chili cultivation, the use of humic acid needs to be accompanied with NPK fertilizers at a reduced amount, along with the increase in the dose of humic acid.
Analyzing STEM Students’ Critical Thinking Performance: Literacy Study on the Polymer Film Fabrication Process Irradiated with Gamma Rays
Authors: Bilad Muhammad Roil , Doyan Aris , Susilawati Susilawati
Published: January 2023

The reliability of pedagogical practice is highly dictated by how it enhances science, technology, engineering, and mathematics (STEM) students’ critical thinking achievement. Adequate pedagogical practice is thus needed in line with the demands of STEM learning in the 21st century, namely achieving optimal critical thinking. This paper reports this pedagogical practice on a topic of polymer film fabrication irradiated with gamma rays. The specific objective was to analyze STEM students’ critical thinking performance in literacy of the aforementioned topic. It is an exploratory study with an experimental method. Only one treatment group was involved, they were STEM students attending the Material Physics Courses. By employing valid critical thinking instruments and adequate methods of analysis, the findings show that literacy on the assigned topic significantly improved STEM students’ CT skills. It was proven that the mean scores of CT indicators have increased in all aspects of the CT assessed. The statistical analysis confirmed that there were significant differences in the CT skills of STEM students between the observations before and after the learning process intervention. The implication of this study is that pedagogical interventions integrated with studies on advanced material modification technology could be effectively used for creating inspiring STEM learning, especially for training STEM students’ critical thinking ways.
Large Locally Advanced Duodenal Gastrointestinal Stromal Tumor (GIST) Successfully Managed by Combined Use of Neoadjuvant Imatinib and Surgical Resection
Authors: H Yeap, J. , G Tan, P. , M Leow, V. , U Ramasamy,
Published: January 2023

Duodenal GISTs are rare mesenchymal neoplasms of the gastrointestinal tract. The usual presentation is gastrointestinal bleeding or abdominal pain. They can be asymptomatic until they reach a considerable size. Tyrosine kinase inhibitors (TKI) are important in high risk GISTs and in locally advanced disease. We report a 65-year-old man with abdominal discomfort, anemia and clinically palpable abdominal mass. A Computed Tomography (CT) scan of the abdomen and pelvis was done which showed a locally advanced duodenal GIST involving second and third part of duodenum. Neoadjuvant imatinib was given to this patient for 6 months. He underwent Whipple’s procedure and right hemicolectomy. The histopathological examination report revealed a high-risk duodenal GIST. Adjuvant Imatinib was continued for 1 month after the operation. He continued to do well with no evidence of disease recurrence based on post-operative CT abdomen and pelvis.
A Comparative Study on Spinal Anesthesia verses General Anesthesia for Laparoscopic Cholecystectomy
Authors: Shoman Dr. Mohammed Mohiuddin , Haque Dr. Mohammad Mahbub-Ul , Tariquzzaman Dr. Md. , Ahmmed Dr. Mustaq , Sultana Dr. Nargis , Sharmin Dr. Bedoura
Published: January 2023

Background: The main goal of anesthetic management in patients undergoing surgical procedures of laparoscopy includes the management of pneumoperitoneum. Generally, laparoscopic cholecystectomy is done under general anesthesia, but a large number of patients with major medical problems sometimes cannot tolerate such anesthesia where thoracic spinal anesthesia may be suitable. Aim of the Study: The aim of this study was to compare spinal anesthesia verses general anesthesia for laparoscopic cholecystectomy regarding the efficacy and outcomes. Methods: This prospective comparative study was conducted in the Department of Anaesthesia & ICU, Mugda Medical College & Hospital, Dhaka, Bangladesh during the period from January 2021 to December 2021. A total 60 patients were enrolled in this study as study population. Patients with physical status ASA I and II were selected as the study population and randomly divided to undergo laparoscopic cholecystectomy with low-tension pneumoperitoneum with CO2 under general anesthesia (n=30) or spinal anesthesia (n=30). Propofol, rocuronium, fentanyl, sevoflurane and tracheal intubation were used for general anesthesia. On the other hand, to achieve a sensorial level of T3, hyperbaric bupivacaine (15 mg) and fentanyl (20 µg) were used for the spinal anesthesia. Data regarding intraoperative parameters, postoperative pain, complications and recovery cost were compared between both groups. Results: In this study, in analyzing the perioperative comparison of mean ±SD VAS scores in both the general and spinal anesthesia groups we observed that in group 1 after 4, 8, 12 and 24 hours VAS (Visual analogue score) scores were found as 1.21±1.02, 1.62±1.35, 1.59±1.38 and 1.02±0.54 respectively which were found as 2.24±1.15, 3.29±1.62, 3.61±1.28 and 2.33±1.49 respectively in group 2. Between both the groups, in all the reading of VAS scores (4, 8, 12 and 24 hours) we found significant correlations between the groups where the P values ...........
Platelet Rich Plasma (PRP) Therapy in Pediatric Surgical Wound Care My Experience in a Tertiary Care Hospital in Bangladesh
Authors: Mahmud Dr. S.M. Khalid , Laizu Dr. Jahanara , Rashid Dr. Aminur , Islam Dr. Aminul , Mahmud Dr. S. M.
Published: January 2023

Background: In recent years, platelet-rich plasma (PRP) has been used in complicated pediatric surgical wound care; burn wound repair, plastic surgery, bone and tendon ligament injury repair and other treatment. Clinical studies indicate that, PRP has a good curative effect on wound care. But in Bangladesh, we have very limited research- based information regarding the outcome of platelet rich plasma (PRP) therapy in complicated pediatric surgical wound care. Aim of the Study: The aim of this study was to evaluate the outcome of platelet rich plasma (PRP) therapy in complicated pediatric surgical wound care. Methods: This prospective observational study was conducted in Bangladesh Shishu Hospital & Institute Dhaka, Bangladesh during the period from January 2021 to June 2022. In total 34 pediatric patients with complicated surgical wound were recruited as the study population. In all cases, the treatment procedure was carried out using autologous donations. Collected data were processed, analyzed and disseminated by using MS Excel and SPSS version 23.0 program as per necessity. Results: In this observational study, in analyzing the final outcomes we observed that, among total 34 complicated pediatric patients with surgical wound, in more than one third of the cases (68%) wounds were healed whereas in the rest 32% cases wound were not healed. The mean ±SD hospital staying period was found as 6.45±2.16 days whereas the mean ±SD healing time was found as 11.47±3.29 weeks. Conclusion: As per the findings of this study we can conclude that, platelet-rich plasma (PRP) has a good curative effect on complicated pediatric surgical wound care. This study can provide reliable evidence for the clinical use of PRP in the clinical cure/repair of several wound.
Public Cloud to Cloud Repatriation Trend
Authors: Jewargi Kiran
Published: January 2023

Cloud repatriation is the process of moving a workload or application from a public cloud to an on-premises or private cloud. The statistics of cloud repatriation, its possible effects, and the justifications for company adoption are all included in the paper. According to recent estimates, in 2021, over 80% of US businesses will pull some workloads from the public cloud. The statistic of the Public Cloud to Cloud Repatriation Trend initially seems to indicate a significant return to on-premises systems.
Home Nursing Practice in Japan during the COVID-19 Pandemic
Authors: Keiko Hattori
Published: January 2023

Home healthcare in Japan has changed with the times. Currently, Japan's population is about 130 million, and the aging rate of those over 65 is about to reach 30%. According to a survey, about 60% of the Japanese population would rather die at home than in a hospital. In Japan, there is a long-term care insurance system that allows people to live at home even if they are ill, and there is a support system that allows people to live in the community by utilizing various social resources. The system is designed to support people to live in their own way in the community. The role of a visiting nurse is to support people so that they can live their lives in the community in their own way. Practical training is provided to learn the role of the home nursing. We examined the extent to which nursing students were affected by the coronavirus for two years, in 2020 and 2021. The method of investigation was a comparison of the content of the practicum and the characteristics of the patients the students received during the practicum. Half of the time, the coronavirus replaced the practice on campus. In addition, the number of pediatric patients accepted was reduced. The nursing students' home nursing practice has been conducted without loss of learning opportunities while taking thorough infection control measures.
The Acquisition of the Spanish Trill (/R/) by Child Heritage Speakers: An Overview and Research Proposal
Authors: Marcano Zayra
Published: January 2023

I propose an analysis on the acquisition of the alveolar trill /r/ by Spanish-speaking children as a heritage language. I aim to determine to what extent the acquisition of the trill by these speakers may differ from the same process in monolingual children. To that end, I will recruit twenty children Spanish-English bilingual heritage speakers (3-6 years of age), and twenty monolingual children of the same age who have never been exposed to another language. To collect the data, I will schedule brief Zoom meetings with the parents of the participants, and I will ask them to connect with the children to play a quick game (a picture-naming task). I will carefully listen to the recordings and examine the participant’s accuracy to produce the acoustic features of the Spanish trill. I will analyze all the tokens acoustically using PRAAT (Boersma & Weenink, 2017). The research hopes to be a contribution in the field of phonological acquisition of Spanish in bilingual settings, and to fill a gap in the literature regarding the development of the trill by heritage speakers.
The Place of Lalle (Henna) in the Hausa Sociocultural and Tradimedical Practices
Authors: Gummi Dr. Musa Fadama , Sani Abu-Ubaida
Published: January 2023

This paper explored the sociocultural, tradimedical, and religious relevance of henna in the Hausa land. The scope is limited to the old Sokoto province, now comprising three states. The research employed a survey method to obtain data from two strata sampled populations through one-to-one interviews. The research has found henna to be a shrub of enormous value and great relevance in the Hausa culture. That includes its relevance and values in different domains of life, including health, religion, as well as socio-economic dealings. However, despite the numerous uses of the henna plant in Hausa culture, it is observed that henna plant cultivation has greatly reduced. Its usage is almost substituted with modern artificial products. It is gradually getting extinct as its cultivation has greatly reduced in most areas of the region (Sokoto province). The paper finally suggested among others that the government and other relevant parastatals should see to the reviving and modernizing the traditional practices, including by supporting the local farmers, conducting clinical research on the product, as well as technologically processing it.
Nitazoxanide in Acute Rotavirus Diarrhea- A Randomized Controlled Trial Study in a Tertiary Care Hospital in Bangladesh
Authors: Islam Dr. Md. Saiful , Ahmed Dr. Syed Shafi , Mahmud Dr. Salahuddin , Mamun Dr. Abdullah Al , Hasan Dr. Md. Kamrul , Hasan Nazmul , Halder Dr. Kanta , Tisha Dr. Shahrina Afroze
Published: January 2023

Background: Acute rotavirus diarrhea is one of the leading cause of morbidity and mortality in children younger than 5 years. Nitazoxanide, an antiparasitic agent, acts by inhibiting the maturation of rotavirus viral protein 7 thus interferes with viral morphogenesis. Aim of the study: was to evaluate the role of nitazoxanide in the treatment of acute rotavirus diarrhea in 6 months to 2 years aged children. Methods: This randomized controlled trial was conducted at Bangladesh Shishu Hospital & Institute, Dhaka, Bangladesh from June 2018 to July 2020. A total of 70 children with acute onset diarrhea of <48 hours. duration was included in this study. All the studied patients were divided into two equal groups (group I and group II) by lottery, each comprising 35 children. The groupI represented the study group who received standard treatment of diarrhea plus oral nitazoxanide (15mg/kg/day) twice daily for 3 days and the group II is the control group received standard treatment only. Results: Study demonstrated that maximum number of patients 22 (31.4%) were between 14-17 months of age group and 36% patients came from rural, 64% from urban areas. Study showed before commencement of treatment most of the patients in both groups experienced some dehydration, vomiting, fever, & abdominal distension. At 48 hours’ improvement was observed in both groups, comparatively higher in group I. Difference of some dehydration and vomiting improvement between two groups were statistically significant (p <0.05). After 3 days’ treatment normal stool consistency was found in 24(68.5%) patients in group I & 10 (28.5%) in group II patients. The difference was also statistically significant (p=<0.05). Mean time of resolution of diarrhea 62.5 hours in Group-I and 96.5 hours in group-II. Compared to the group II, group I showed decrease in mean time of resolution of diarrhea (p= 0.001). The mean duration of hospital stay was prolonged in group-II (86.5 hours vs. 102.5 hours in group I & II respectively), the difference was statistically significant (p˂0.05). Conclusion: In the present study, oral nitazoxanide was found effective in the treatment of acute rotavirus diarrhea in 6 months to 2 years old children.
Rehabilitation- Is a Vital Component of Universal Health Coverage
Authors: Mahadevaswamy Mr. R. K. , V Mrs. Manjula K.
Published: January 2023

Rehabilitation is important, as are other facets of universal health coverage such efficient illness prevention, treatment, and palliative care. A person who has undergone rehabilitation can participate in school, job, recreation, and important life responsibilities including caring for family members. Rehabilitation enables a child, adult, or senior to be as independent as possible in daily activities. A health issue that could be treated by rehabilitation affects an estimated 2.4 billion individuals worldwide. The need for rehabilitation services is anticipated to increase globally as a result of changes in population health and features. People are living longer but with more chronic illness and incapacity, for instance. Rehabilitation needs are now mostly unmet. More than half of the population does not obtain the necessary rehabilitation services in several low- and middle-income nations. Rehabilitation and other healthcare programs have been severely impacted by the COVID-19 pandemic.
The Influence of Individual Characteristics, Internal and External Factors of Postpartum Mothers with Baby Blues Syndrome in Rural and Urban Areas in Kupang City
Authors: Mones Servasia Yosefina , Lada Christina Olly , Jutomo Lewi , Trisno Idawati , Roga Anderias Umbu
Published: January 2023

Baby Blues Syndrome (BBS) is a psychological disorder in postpartum mothers. This can interfere with milk production. The mother cannot provide adequate breast milk to the baby and cannot take care of the baby properly. This study was conducted in two health center in rural and two in urban. This was a comparative descriptive design using with cross sectional approach. The number of respondents was 119 postpartum mothers taken by purposive sampling technique. Data were collected through questionnaires and interviews. The percentage incidence of BBS was 75.6%. From the results of Chi-Squre test, the factors that significantly influence the incidence of BBS include education (p=0,023), type delivery (p=0,025), family economic status (p=0,005), and social support (p=0,039). From the different Mann Whitney Test, it was found that there were differences in factors between rural and urban areas, including education (Sig.2 Tailed=0,029), occupation (Sig. 2 Tailed=0,001), nutritional status (Sig. 2 Tailed=0,001), parity (Sig. 2 Tailed=0,010), type delivery (Sig.2 Tailed=0,000), and family economic status (Sig.2 Tailed=0,000). Mothers with low family economic status and education in rural areas need capacity building through training (cooking and sewing) and education (counseling). Class activities for pregnant women by involving partners or families to increase social support, as well as counseling about the consequences of pregnancy out of wedlock and mental health for pregnant women to promote better physical, mental and social health.
PENGENDALIAN PERSEDIAAN VAKSIN PADA DINAS KESEHATAN KABUPATEN HULU SUNGAI SELATAN
Authors:   Politeknik Negeri Tanah Laut, Hayatie Marliza Noor , Aitama Muhammad Aditya
Published: January 2023

In the case of vaccination in Indonesia, the problem that often occurs is the shortage of vaccine supplies in one area while in other areas there is a problem of excess vaccine supply which results in the accumulation of goods in warehouses. The purpose of this study is to determine which type of vaccine is more widely used in the community so that there is no excess or shortage of supplies. This study uses the Activity Based Costing (ABC) inventory control analysis method to determine which vaccine is more priority and which is more widely used in Hulu Sungai Selatan Regency. The type of data used in this study is quantitative data, namely data on entry and expenditure of vaccine supplies in 2021 at the Hulu Sungai Selatan District Health Office. The data source used is secondary data with documentation collection techniques. Based on the results of research using the ABC method, the stock of vaccine types that are more prioritized for use by the community is the type of group A vaccine, namely with 2 types of vaccines, namely Sinovac 1 ml and Sinovac 5 ml.
UJI TOKSISITAS KITOSAN CANGKANG KERANG BULU (Anadara antiquata) DENGAN METODE BRINE SHRIMP LETHALITY TEST (BSLT)
Authors:   Program Studi Farmasi, Universitas Muslim Nusantara Al Washliyah, Sepvina Nadila Indra , Ridwanto Ridwanto , Rani Zulmai
Published: January 2023

Shellfish is one of Indonesia's fishery commodities which is increasing every year, one of which is blood clams and feather shells, which are easily found in Southeast Asia and East Asia. Shellfish also have great potential so that it has an impact on the increasing waste that is allowed to accumulate without any handling of the pollution that exists in the environment and society. One alternative to the use of waste from feather shells to have a high use value is to isolate it into chitosan. The purpose of this study was to investigate the utilization of shellfish waste into chitosan and to determine the LC50 value of the chitosan produced. The analysis carried out was the toxicity test of chitosan from shellfish shell waste on Artemia salina Leach shrimp larvae using the Brine Shrimp Lethalitiy Test (BSLT) method with various concentrations of 100; 250; 500; 750; and 1000 Âµg/mL, and determining the value of LC50 by probit analysis. Based on the results of the toxicity test of chitosan from shellfish waste, the LC50 value was Âµg/mL. These results indicate that chitosan from shellfish waste has no toxic effect on Artemia salina Leach shrimp larvae.
AKTIVITAS ANTIOBESITAS DAN ANTIINFLAMASI EKSTRAK ETANOL DAUN KATUK (Sauropus androgynus (L.) Merr) PADA TIKUS WISTAR JANTAN OBESITAS
Authors:   Fakultas Farmasi Universitas Bhakti Kencana, Istiqomah Aulia Nurfazri , Putra Hendra Mahakam , Aligita Widhya , Risa O Betti
Published: January 2023

Obesity is currently a disease with a prevalence that continues to increase every year and is a significant risk factor for cardiovascular disease. The relationship between obesity and inflammation is characterized by increased levels of TNF- which triggers inflammation. This study was conducted to determine the activity of katuk (Sauropus androgynus (L.) Merr) leaves as anti-obesity and anti-inflammatory properties. The study was conducted with a preventive method on white male wistar rats aged 2-3 months and body weight of 180-200 g. The test animals were divided into 6 groups that were induced by high-fat and carbohydrate diets except the normal group and were measured for anti-obesity and anti-inflammatory parameters. The results showed that katuk (Sauropus androgynus (L.) Merr) leaves can maintain activity as an anti-obesity and anti-inflammatory in test rats. Katuk leaf ethanol extract at a dose of 300 mg/kgBW has an effective activity as an anti-obesity, while at a dose of 150 mg/kgBW it has an anti-inflammatory activity.
POTENSI DAUN TEH HIJAU (Camellia sinensis) SEBAGAI INHIBITOR MAIN PROTEASE (Mpro) COVID-19: SEBUAH STUDI MOLECULAR DOCKING
Authors:   Profesi Kedokteran Umum, Fakultas Kedokteran, Universitas Sriwijaya, Hamzah Haidar Ali , Ernanto Junoretta Haviva ,   Profesi Kedokteran Umum, Fakultas Kedokteran, Universitas Sriwijaya, Afladhanti Putri Mahirah ,   Profesi Kedokteran Umum, Fakultas Kedokteran, Universitas Sriwijaya, Theodorus Theodorus ,   Departemen Farmakologi, Fakultas Kedokteran, Universitas Sriwijaya
Published: January 2023

Green tea is an herbal plant that has active compounds including anti-inflammatory, antioxidant, anti-allergic, and antiviral compounds. A previous study, flavonoid compound in tea leaves has been proven as antiviral. The development of effective antiviral drugs against COVID-19 remains a challenge for researchers across the world. A previous study investigated the role of the main protease enzyme (Mpro) which is useful in the viral life cycle as a promising drug target. This study aims to know the potential compounds of green tea leaves as a COVID-19 Mpro inhibitor using molecular docking. 12 compounds and lopinavir were used. Lipinski analysis was carried out to assess potential compounds as a drug. Docking was carried out by Autodock Tools 1.5.6 and Autodock Vina. The visualization was carried out by Discovery Studio v16. The results showed that all compounds compiled the criteria as a drug based on Lipinski rules. Catechin and epicatechin have the same energy bond as lopinavir with a binding energy of -7.1 kcal/mol. Catechin gallate and epicatechin gallate have the strongest energy bond with a binding energy of -9.0 and -8.2 kcal/mol. All compounds bind in the active site of the COVID-19 Mpro so they are competitive inhibitor. Catechin gallate is the strongest inhibitors.