bluuebunny/crossref_metadata_2025 huggingface dataset:
The Relationship between Energy Production and GDP: Evidence from Selected European Economies
Authors: Szustak Grażyna , Dąbrowski Piotr , Gradoń Witold , Szewczyk Łukasz
Published: December 2021

The aim of this article was to investigate the possible relationship between energy production and GDP growth. This problem is of a crucial importance because as a numerous studies show, it is difficult to give an unambiguous answer to the question of whether there is a relationship between GDP and energy production and what direction it takes if it exists, i.e., whether energy production drives GDP growth or GDP growth drives energy production. The research conducted by the authors used data on hourly power production in MWh/h averaged over a whole day, which were converted into total quarterly production. The data were divided in terms of the type of energy into conventional, renewable, other and total. Next, the correlation coefficient was calculated for proper data sets in order to determine whether there was a correlation between the variables. The main conclusion from the study is the fact that a correlation measured with the Pearson correlation coefficient is not reflected in the data. Changes in power production independent of the source of power do not influence the GDP directly. Naturally, in some countries, the connection between power production and GDP was stronger; however, comparing this to the rest of the researched countries, where correlation was low or even extremely low, it can be seen that the relationship is random. This study should be seen as an introductory one with a perspective of broadening research in terms of causality between variables, which, nowadays, has great application in terms of climate change and sustainable development.
The Impact of Local Anti-Smog Resolution in Cracow (Poland) on the Concentrations of PM10 and BaP Based on the Results of Measurements of the State Environmental Monitoring
Authors: Flaga-Maryańczyk Agnieszka , Baran-Gurgul Katarzyna
Published: December 2021

As a result of conducted air quality policy, including recent legal regulations (the local anti-smog resolution), the number of individual solid fuel heating devices in Cracow (Poland) gradually decreased. Reports on air quality in the city indicate that the concentration of pollutants in Cracow’s air shows a downward trend. However, a similar tendency in terms of improving air quality is also observed in the entire voivodeship, where, as a result of analogous although less radical measures, the number of individual solid fuel heating devices is also decreasing. The paper discusses the impact of legal regulations in Cracow on the improvement of air quality in the context of changes taking place in nearby cities. Trends in changes in PM10 and BaP (PM10) concentrations are analyzed. The rate of decline of the analyzed pollutants concentrations is estimated with the use of nonparametric linear regression. Analysis showed that the rate of decline in the average annual concentrations of PM10 and BaP (PM10) in Cracow is always higher than for the analyzed cities of the Malopolskie Voivodeship. The difference is more pronounced with regard to the months of the heating season. The rate of changes for the average annual BaP (PM10) concentrations in Cracow, compared to other analyzed cities of the Malopolskie Voivodeship, is more intensive than in the case of PM10 concentrations (1.5 times stronger with regard to the months of the heating season). Since the concentration of BaP (PM10) is a better indicator of the effects of liquidation of high-emission furnaces than the concentration of PM10, it can be concluded that the impact of actions related to the improvement of air quality in Cracow in the context of changes taking place in selected cities of the Malopolskie Voivodeship is more visible.
Fuzzy-Based Investigation of Challenges for the Deployment of Renewable Energy Power Generation
Authors: Shabbiruddin  , Kanwar Neeraj , Jadoun Vinay Kumar , Alotaibi Majed A. , Malik Hasmat , E. Nassar Mohammed
Published: December 2021

Studying and analyzing the challenges that the renewable energy sector faces can help evaluate the risks and improve the planning. This research is done by considering the challenges in the implementation of sustainable generation of electricity through RESs in India, based on factors, including technical, financial, involvement, support, and others. The triangular fuzzy number (TFN) method, based on fuzzy logic concept, is used to analyze the challenges in this study. In general, TFN comprises of three numbers, likewise Gaussian fuzzy numbers, trapezoidal fuzzy numbers also exist. The classified sets of numbers are denotations to decision-makers’ perspective or a choice towards the criterion preference. Although alternatives are many to design a fuzzy set depending on elements count, the TFNs are the ones considered as actual representations of a fuzzy number. On the other hand, cases the Gaussian or trapezoidal, are manifestations of fuzzy intervals. Another argument is that the membership function shape corresponding to the number of fuzzy set elements is largely dependent on the study. The challenges identified along with analysis in this paper will help the industry, governments, and policymakers focus and tackle essential issues to facilitate further the deployment of RESs in India towards a more sustainable country.
Hydrogen Containing Nanofluids in the Spark Engine’s Cylinder Head Cooling System
Authors: Balitskii Alexander , Kindrachuk Myroslav , Volchenko Dmytro , Abramek Karol F. , Balitskii Olexiy , Skrypnyk Vasyl , Zhuravlev Dmytro , Bekish Iryna , Ostashuk Mykola , Kolesnikov Valerii
Published: December 2021

The article is devoted to the following issues: boiling of fluid in the cooling jacket of the engine cylinder head; agents that influenced the thermal conductivity coefficient of nanofluids; behavior of nanoparticles and devices with nanoparticles in the engine’s cylinder head cooling system. The permissible temperature level of internal combustion engines is ensured by intensification of heat transfer in cooling systems due to the change of coolants with “light” and “heavy” nanoparticles. It was established that the introduction of “light” nanoparticles of aluminum oxide Al2O3 Al2O3 into the water in a mass concentration of 0.75% led to an increase in its thermal conductivity coefficient by 60% compared to the base fluid at a coolant temperature of 90 °C, which corresponds to the operating temperature of the engine cooling systems. At the indicated temperature, the base fluid has a thermal conductivity coefficient of 0.545 Wm2×°C W/(m °C), for nanofluid with Al2O3 particles its value was 0.872 Wm2×°C. At the same time, a positive change in the parameters of the nanofluid in the engine cooling system was noted: the average movement speed increased from 0.2 to 2.0 m/s; the average temperature is in the range of 60–90 °C; heat flux density 2 × 102–2 × 106 Wm2; heat transfer coefficient 150–1000 Wm2×°C. Growth of the thermal conductivity coefficient of the cooling nanofluid was achieved. This increase is determined by the change in the mass concentration of aluminum oxide nanoparticles in the base fluid. This will make it possible to create coolants with such thermophysical characteristics that are required to ensure intensive heat transfer in cooling systems of engines with various capacities.
Limbic Encephalitis Associated with COVID-19
Authors: Shnayder Natalia A. , Sirbiladze Timur K. , Demko Irina V. , Petrova Marina M. , Nasyrova Regina F.
Published: December 2021

Limbic encephalitis (LE) is an inflammatory disease of the brain, in which lesion is anatomically limited in structures of the limbic system. In some cases, LE can start with symptoms of limbic dysfunction with further involvement of other regions of the brain. Classic LE syndrome includes such symptoms as the development of personality disorders, depression, sleep disorders, epileptic seizures, hallucinations and cognitive disorders (short-term and long-term memory impairment). The information of clinical examination, electroencephalogram (EEG), magnetic resonance imaging (MRI) and cerebrospinal fluid studies (CSF) suggest the diagnosis of LE in most patients with Coronavirus Disease 2019 (COVID-19).
A CFD Comparative Study of Bubbling Fluidized Bed Behavior with Thermal Effects Using the Open-Source Platforms MFiX and OpenFOAM
Authors: Reyes-Urrutia Andrés , Venier Cesar , Mariani Néstor Javier , Nigro Norberto , Rodriguez Rosa , Mazza Germán
Published: December 2021

This work studies the performance of two open-source CFD codes, OpenFOAM and MFiX, to address bubbling fluidized bed system at different temperature and heat transfer conditions. Both codes are used to predict two parameters that are relevant for the design of fluidized units: the minimum fluidization velocity as a function of the temperature of the bed and wall-to-bed heat transfer coefficient from a lateral wall and from internal tubes. Although the CFD solvers are structuraly similar, there are some key differences (available models, meshing techniques, and balance formulations) that are often translated into differences in the fields prediction. The computational results are compared between both codes and against the experimental data. The minimum fluidization velocity can be correctly predicted with both codes at different temperatures while, in general, for the heat transfer and the fluidization patterns, MFiX shows slightly more accurate results compared to OpenFOAM but with low versatility for meshing curved geometries which might translate into higher computational costs for the same level of accuracy.
The Hydrodynamic Behavior of Vortex Shedding behind Circular Cylinder in the Presence of Group Focused Waves
Authors: Abroug Iskander , Abcha Nizar , Mejri Fahd , Turki Emma Imen , Ojeda Elena
Published: December 2021

Vortex shedding behind an elastically mounted circular cylinder in the presence of group focused waves propagating upstream was investigated using a classical approach (time series and FFT) and nonclassical approach (complex 2D Morlet wavelets). Wavelet analysis emerged as a novel solution in this regard. Our results include wave trains with different nonlinearities propagating in different water depths and derived from three types of spectra (Pierson–Moskowitz, JONSWAP (γ = 3.3 or γ = 7)). It was found that the generated wave trains could modify regimes of shedding behind the cylinder, and subharmonic frequency lock-in could arise in particular situations. The occurrence of a lock-in regime in the case of wave trains propagating in intermediate water locations was shown experimentally even for small nonlinearities. Moreover, the application of time-localized wavelet analysis was found to be a powerful approach. In fact, the frequency lock-in regime and its duration could be readily identified from the wavelet-based energy and its corresponding ridges.
Promise of Persistent Multi-Messenger Astronomy with the Blazar OJ 287
Authors: Valtonen Mauri J. , Dey Lankeswar , Gopakumar Achamveedu , Zola Staszek , Komossa S. , Pursimo Tapio , Gomez Jose L. , Hudec Rene , Jermak Helen , Berdyugin Andrei V.
Published: December 2021

Successful observations of the seven predicted bremsstrahlung flares from the unique bright blazar OJ 287 firmly point to the presence of a nanohertz gravitational wave (GW) emitting supermassive black hole (SMBH) binary central engine. We present arguments for the continued monitoring of the source in several electromagnetic windows to firmly establish various details of the SMBH binary central engine description for OJ 287. In this article, we explore what more can be known about this system, particularly with regard to accretion and outflows from its two accretion disks. We mainly concentrate on the expected impact of the secondary black hole on the disk of the primary on 3 December 2021 and the resulting electromagnetic signals in the following years. We also predict the times of exceptional fades, and outline their usefulness in the study of the host galaxy. A spectral survey has been carried out, and spectral lines from the secondary were searched for but were not found. The jet of the secondary has been studied and proposals to discover it in future VLBI observations are mentioned. In conclusion, the binary black hole model explains a large number of observations of different kinds in OJ 287. Carefully timed future observations will be able to provide further details of its central engine. Such multi-wavelength and multidisciplinary efforts will be required to pursue multi-messenger nanohertz GW astronomy with OJ 287 in the coming decades.
3D Genome Organization: Causes and Consequences for DNA Damage and Repair
Authors: Carré-Simon Ànnia , Fabre Emmanuelle
Published: December 2021

The inability to repair damaged DNA severely compromises the integrity of any organism. In eukaryotes, the DNA damage response (DDR) operates within chromatin, a tightly organized DNA–histone complex in a non-random manner within the nucleus. Chromatin thus orchestrates various cellular processes, including repair. Here, we examine the chromatin landscape before, during, and after the DNA damage, focusing on double strand breaks (DSBs). We study how chromatin is modified during the repair process, not only around the damaged region (in cis), but also genome-wide (in trans). Recent evidence has highlighted a complex landscape in which different chromatin parameters (stiffness, compaction, loops) are transiently modified, defining “codes” for each specific stage of the DDR. We illustrate a novel aspect of DDR where chromatin modifications contribute to the movement of DSB-damaged chromatin, as well as undamaged chromatin, ensuring the mobilization of DSBs, their clustering, and their repair processes.
Additive and Dominance Genomic Analysis for Litter Size in Purebred and Crossbred Iberian Pigs
Authors: Srihi Houssemeddine , Noguera José Luis , Topayan Victoria , Martín de Hijas Melani , Ibañez-Escriche Noelia , Casellas Joaquim , Vázquez-Gómez Marta , Martínez-Castillero María , Rosas Juan Pablo , Varona Luis
Published: December 2021

INGA FOOD S. A., as a Spanish company that produces and commercializes fattened pigs, has produced a hybrid Iberian sow called CASTÚA by crossing the Retinto and Entrepelado varieties. The selection of the parental populations is based on selection criteria calculated from purebred information, under the assumption that the genetic correlation between purebred and crossbred performance is high; however, these correlations can be less than one because of a GxE interaction or the presence of non-additive genetic effects. This study estimated the additive and dominance variances of the purebred and crossbred populations for litter size, and calculated the additive genetic correlations between the purebred and crossbred performances. The dataset consisted of 2030 litters from the Entrepelado population, 1977 litters from the Retinto population, and 1958 litters from the crossbred population. The individuals were genotyped with a GeneSeek® GGP Porcine70K HDchip. The model of analysis was a ‘biological’ multivariate mixed model that included additive and dominance SNP effects. The estimates of the additive genotypic variance for the total number born (TNB) were 0.248, 0.282 and 0.546 for the Entrepelado, Retinto and Crossbred populations, respectively. The estimates of the dominance genotypic variances were 0.177, 0.172 and 0.262 for the Entrepelado, Retinto and Crossbred populations. The results for the number born alive (NBA) were similar. The genetic correlations between the purebred and crossbred performance for TNB and NBA—between the brackets—were 0.663 in the Entrepelado and 0.881 in Retinto poplulations. After backsolving to obtain estimates of the SNP effects, the additive genetic variance associated with genomic regions containing 30 SNPs was estimated, and we identified four genomic regions that each explained > 2% of the additive genetic variance in chromosomes (SSC) 6, 8 and 12: one region in SSC6, two regions in SSC8, and one region in SSC12.
Causal Association between Periodontal Diseases and Cardiovascular Diseases
Authors: Zhou Mengchen , Dong Jiangtao , Zha Lingfeng , Liao Yuhua
Published: December 2021

Observational studies have revealed that dental diseases such as periodontitis and dental caries increase the risk of cardiovascular diseases (CVDs). However, the causality between periodontal disease (PD) and CVDs is still not clarified. In the present study, two-sample Mendelian randomization (MR) studies were carried out to assess the association between genetic liability for periodontal diseases (dental caries and periodontitis) and major CVDs, including coronary artery disease (CAD), heart failure (HF), atrial fibrillation (AF), and stroke—including ischemic stroke as well as its three main subtypes—based on large-scale genome-wide association studies (GWASs). Our two-sample MR analyses did not provide evidence for dental caries and periodontitis as the causes of cardiovascular diseases; sensitivity analyses, including MR–Egger analysis and weighted median analysis, also supported this result. Gene functional annotation and pathway enrichment analyses indicated the common pathophysiology between cardiovascular diseases and periodontal diseases. The associations from observational studies may be explained by shared risk factors and comorbidities instead of direct consequences. This also suggests that addressing the common risk factors—such as reducing obesity and improving glucose tolerance—could benefit both conditions.
Seismic Soil Characterization to Estimate Site Effects Induced by Near-Fault Earthquakes: The Case Study of Pizzoli (Central Italy) during the Mw 6.7 2 February 1703, Earthquake
Authors: Chiaradonna Anna , Spadi Marco , Monaco Paola , Papasodaro Felicia , Tallini Marco
Published: December 2021

Many of the urban settlements in Central Italy are placed nearby active faults and, consequently, the ground motion evaluation and seismic site effects under near-fault earthquakes are noteworthy issues to be investigated. This paper presents the results of site investigations, the seismic site characterization, and the local seismic response for assessing the effects induced by the Mw 6.7 2 February 1703, near-fault earthquake at the Madonna delle Fornaci site (Pizzoli, Central Italy) in which notable ground failure phenomena were observed, as witnessed by several coeval sources. Even though recent papers described these phenomena, the geological characteristics of the site and the failure mechanism have never been assessed through in-situ investigations and numerical modeling. Within a project concerning the assessment of soil liquefaction potential and co-seismic ground failure, deep and shallow continuous core drilling, geophysical investigations and in-hole tests have been carried out. Subsequently, the geotechnical model has been defined and the numerical quantification of the different hypotheses of failure mechanisms has been evaluated. Analyses showed that liquefaction did not occur, and the excess pore water pressure induced by the shaking was not the source of the ground failure. Therefore, it was hypothesized that the sinkhole was likely caused by earthquake-induced gas eruption.
Reviewing the UK’s Action Levels for the Management of Dredged Material
Authors: Mason Claire , Vivian Chris , Griffith Andrew , Warford Lee , Hynes Clare , Barber Jon , Sheahan David , Bersuder Philippe , Bakir Adil , Lonsdale Jemma-Anne
Published: December 2021

Action Levels (ALs) are thresholds which are used to determine whether dredged material is suitable for disposal at sea by providing a proxy risk assessment for potential impacts to biological features such as fish and benthos. This project tested proposed scenarios for changes to the UK Action Levels to determine the likely implications for navigational dredge licensing in England and Wales. Approximately 3000 sample data records from 2009 to 2018 were collated with varying numbers of concentrations for contaminant parameters including trace metals, organotins, polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs) and polybrominated diphenyl ethers (PBDEs). Initially, these data were assessed using current ALs to determine the percentages of the samples with levels below AL1 (generally acceptable for disposal), between AL1 and AL2 and those showing levels above AL2 (generally unacceptable for disposal). These results were then used to compare with the results of the proposed new AL scenarios for each contaminant type derived from literature reviews and historic data. The results indicate that there are changes to the ALs which could be made such as updating the current ALs with the revised ALs, as well as the introduction of ALs where there are currently none set. The benefits of changing the ALs include reducing contaminant disposal to the marine environment and increased transparency in decision making. Any proposed scenarios will need to be phased in carefully in full liaison with stakeholders.
Deep Learning on Histopathology Images for Breast Cancer Classification: A Bibliometric Analysis
Authors: Khairi Siti , Bakar Mohd , Alias Mohd , Bakar Sakhinah , Liong Choong-Yeun , Rosli Nurwahyuna , Farid Mohsen
Published: December 2021

Medical imaging is gaining significant attention in healthcare, including breast cancer. Breast cancer is the most common cancer-related death among women worldwide. Currently, histopathology image analysis is the clinical gold standard in cancer diagnosis. However, the manual process of microscopic examination involves laborious work and can be misleading due to human error. Therefore, this study explored the research status and development trends of deep learning on breast cancer image classification using bibliometric analysis. Relevant works of literature were obtained from the Scopus database between 2014 and 2021. The VOSviewer and Bibliometrix tools were used for analysis through various visualization forms. This study is concerned with the annual publication trends, co-authorship networks among countries, authors, and scientific journals. The co-occurrence network of the authors’ keywords was analyzed for potential future directions of the field. Authors started to contribute to publications in 2016, and the research domain has maintained its growth rate since. The United States and China have strong research collaboration strengths. Only a few studies use bibliometric analysis in this research area. This study provides a recent review on this fast-growing field to highlight status and trends using scientific visualization. It is hoped that the findings will assist researchers in identifying and exploring the potential emerging areas in the related field.
Endoscopic Diagnosis of Biliary Stricture Combined with Digital Cholangioscope: A Case Series
Authors: Fukuhara Seiichiro , Iwasaki Eisuke , Kayashima Atsuto , Machida Yujiro , Tamagawa Hiroki , Kawasaki Shintaro , Horibe Masayasu , Hori Shutaro , Abe Yuta , Kitago Minoru , Ogata Haruhiko , Kanai Takanori
Published: December 2021

The endoscopic diagnosis of biliary tract lesions is applied as a non-invasive method; however, its diagnostic accuracy is not yet high. Moreover, digital cholangioscopy is used for directly visualizing the inside of the bile duct, resulting in a more precise biopsy. We present the case series of the outcomes of diagnosis using digital cholangioscopy in patients who underwent cholangioscopy for the evaluation of biliary stenosis in our department between January 2014 and March 2021. The controls were those who underwent a biopsy for biliary stenosis with conventional endoscopic retrograde cholangiopancreatography (ERCP). Background data for each case were collected, and the clinical outcomes by biopsy were evaluated, focusing on the accuracy of the diagnosis. Cholangioscopy was performed in 15 cases, while a conventional biopsy by ERCP was performed in 172 cases. Nine of 15 cases (60.0%) were diagnosed with cholangiocarcinoma. The number of specimens obtained through conventional ERCP and cholangioscopy was 2.5 ± 1.3 and 3.3 ± 1.5, respectively (p = 0.043). The diagnostic accuracy of conventional ERCP and cholangioscopy were 65.7% (113 of 172 cases) and 100%, respectively, which was significantly higher in the group with cholangioscopy. Digital cholangioscopy is useful when the diagnosis of the biliary stricture using the conventional ERCP method is difficult.
Supporting Sign Language Narrations in the Museum
Authors: Partarakis Nikolaos , Zabulis Xenophon , Foukarakis Michalis , Moutsaki Mirοdanthi , Zidianakis Emmanouil , Patakos Andreas , Adami Ilia , Kaplanidi Danae , Ringas Christodoulos , Tasiopoulou Eleana
Published: December 2021

The accessibility of Cultural Heritage content for the diverse user population visiting Cultural Heritage Institutions and accessing content online has not been thoroughly discussed. Considering the penetration of new digital media in such physical and virtual spaces, lack of accessibility may result in the exclusion of a large user population. To overcome such emerging barriers, this paper proposes a cost-effective methodology for the implementation of Virtual Humans, which are capable of narrating content in a universally accessible form and acting as virtual storytellers in the context of online and on-site CH experiences. The methodology is rooted in advances in motion capture technologies and Virtual Human implementation, animation, and multi-device rendering. This methodology is employed in the context of a museum installation at the Chios Mastic Museum where VHs are presenting the industrial process of mastic processing for chewing gum production.
Study of the Influence of Abiotic and Biotic Stress Factors on Horticultural Plants
Authors: Hanaka Agnieszka , Majewska Małgorzata , Jaroszuk-Ściseł Jolanta
Published: December 2021

In changing environmental conditions, horticulture plants are affected by a vast range of abiotic and biotic stresses which directly and indirectly influence plant condition [...]
Raising Children in Risk Neighborhoods from Chile: Examining the Relationship between Parenting Stress and Parental Adjustment
Authors: Sandoval-Obando Eduardo , Alcaide Marta , Salazar-Muñoz Miguel , Peña-Troncoso Sebastián , Hernández-Mosqueira Claudio , Gimenez-Serrano Sofia
Published: December 2021

Introduction: Parenting stress and parental adjustment could implicate key differences in the relational dynamics that parents establish with their children, particularly when families come from vulnerable social contexts. Method: Participants were 142 fathers and mothers from a risk neighborhood of Chile. The variables examined were parenting stress (parental distress, parent–child dysfunctional interaction and difficult child) and parental adjustment (depression, anxiety, and stress). Parents also completed a sociodemographic characterization survey. The statistical analyses were a correlation analysis and multiple linear regression analyses. Results: Overall, not all components of parenting stress were related to parental adjustment. Only parental distress was found as a significant predictor of poor parental adjustment (greater depression, anxiety, and stress), but not parent–child dysfunctional interaction and having a difficult child. Conclusions: The present study findings highlight the influence of stress on parenting as a relevant dimension of research for the improvement of the intervention deployed by the state regarding the protection of vulnerable Chilean children, providing multiple clinical and psychosocial applications for research and intervention purposes.
Effect of Heart Rate Reserve on Prefrontal Cortical Activation While Dual-Task Walking in Older Adults
Authors: Bishnoi Alka , Chaparro Gioella N. , Hernandez Manuel E.
Published: December 2021

Hypertension is considered a risk factor for cardiovascular health and non-amnestic cognitive impairment in older adults. While heart rate reserve (HRR) has been shown to be a risk factor for hypertension, how impaired HRR in older adults can lead to cognitive impairment is still unclear. The objective of this study was to examine the effects of HRR on prefrontal cortical (PFC) activation under varying dual-task demands in older adults. Twenty-eight older adults (50–82 years of age) were included in this study and divided into higher (n = 14) and lower (n = 14) HRR groups. Participants engaged in the cognitive task which was the Modified Stroop Color Word Test (MSCWT) on a self-paced treadmill while walking. Participants with higher HRR demonstrated increased PFC activation in comparison to lower HRR, even after controlling for covariates in analysis. Furthermore, as cognitive task difficulty increased (from neutral to congruent to incongruent to switching), PFC activation increased. In addition, there was a significant interaction between tasks and HRR group, with older adults with higher HRR demonstrating increases in PFC activation, faster gait speed, and increased accuracy, relative to those with lower HRR, when going from neutral to switching tasks. These results provide evidence of a relationship between HRR and prefrontal cortical activation and cognitive and physical performance, suggesting that HRR may serve as a biomarker for cognitive health of an older adult with or without cardiovascular risk.
Analysis of Medical Management in Geriatric Patients in the Hospital Emergency Department by Example of Selected Cities with County Status in Poland: A Retrospective Cohort Study
Authors: Celiński Mariusz , Cybulski Mateusz , Fiłon Joanna , Muszalik Marta , Goniewicz Mariusz , Krajewska-Kułak Elżbieta , Ślifirczyk Anna
Published: December 2021

The aim of this study was to analyse medical management in geriatric patients in the Hospital Emergency Departments in the Biała Podlaska County and Chełm County (Poland) between 2016 and 2018 in a group of patients ≥65 years of age. We analysed medical records of 829 patients transported to Hospital Emergency Departments by Medical Emergency Teams. The research was conducted in the period from June 2019 to March 2020. We analysed emergency medical procedure forms and medical records of patients transported to the hospitals. Cardiovascular diseases were diagnosed in 40% of patients. Mortality cases accounted for 3.1% of the 1200 interventions analysed. Ambulance dispatch resulted in the patient being transported to the Hospital Emergency Departments in more than 2/3 of cases. The concordance between the diagnoses made by the Medical Emergency Teams and those made at the Hospital Emergency Departments was confirmed for 78% patients admitted to the department (n = 647), whereas the concordance of classification at the group level was estimated at 71.7% (n = 594). Further in-patient treatment was initiated in some of the patients admitted to the department (n = 385). The mean time of hospital stay was 10.1 days. In conclusion, differences between the initial diagnosis made by the heads of the Medical Emergency Teams and the diagnosis made by the doctor on duty in the Hospital Emergency Departments depended on the chapter of diseases in the ICD-10 classification, but they were acceptable. The majority of the patients were transported to Hospital Emergency Departments. The most common groups of diseases that require Hospital Emergency Departments admission include cardiovascular diseases, injuries due to external causes, and respiratory diseases. A moderate percentage of patients were qualified for further specialist treatment in hospital departments.
Breaking the Mould: A Theory Explaining How Young Adults Living with WS Learn Life Skills through Music
Authors: Erasmus Ewie
Published: December 2021

This article presents a theory explaining how young adults living with Williams syndrome (WS) learn life skills through music. The article answers the question: What theory explains how young adults living with WS learn life skills through music? The theory presented in this article is informed by principles of care ethics and compassionate music education and theories of wellbeing and flourishing. The theory is further informed by empirical data, including data collected during semi-structured interviews, casual conversations, observations, field notes, and social media and blog posts collected at Berkshire Hills Music Academy, Massachusetts, USA, over six weeks. Thematic analysis was the data analysis strategy. The theoretical proposition represented by the findings is: (i) If young adults living with WS have the opportunity to learn through engagement in music activities within a safe environment in which they are engaged, supported, appreciated, motivated, feel that they belong and feel that they are competent, and (ii) if educators are willing to focus on the abilities of these young adults by putting their needs first, (iii) then young adults living with WS should be able to overcome various challenges and ultimately develop the life skills they need to live well.
Diet and Consumer Behavior in U.S. Vegetarians: A National Health and Nutrition Examination Survey (NHANES) Data Report
Authors: Storz Maximilian Andreas , Müller Alexander , Lombardo Mauro
Published: December 2021

An increasing number of individuals adopt plant-based diets for their potential health benefits. Understanding vegetarians’ dietary behavior in the context of their socioeconomic background is essential for pro-vegetarian messaging and to influence public beliefs about plant food consumption. Thus, this study sought to investigate diet and consumer behaviors in U.S. vegetarians. This is a cross-sectional, population-based study with data from the Nutrition and Health Examination Surveys (2007–2010). Selected items from three modules (diet and nutrition behavior, consumer behavior, and food security) were compared between vegetarians (n = 352) and the general population (n = 14,328). U.S. vegetarians consumed significantly fewer calories and less cholesterol but more fiber than their omnivorous counterparts. Moreover, vegetarians had significantly fewer soft drinks and salty snacks available at home. We also observed significant intergroup differences with regard to the availability of fruit and dark green vegetables. Vegetarians spent less money on eating out and indicated a lower number of not-home-prepared meals and ready-to-eat foods. We found no differences regarding money spent at supermarkets or grocery stores. Our study contributes to a better understanding of dietary and consumer behaviors in vegetarians. We shed a new light on the economic feasibility of vegetarian diets, highlighting that these diets are not necessarily more expensive than an omnivorous diet.
Perinatal Environmental Health Education Intervention to Reduce Exposure to Endocrine Disruptors: The PREVED Project
Authors: El Ouazzani Houria , Fortin Simon , Venisse Nicolas , Dupuis Antoine , Rouillon Steeve , Cambien Guillaume , Gourgues Anne-Sophie , Pierre-Eugène Pascale , Rabouan Sylvie , Migeot Virginie , Albouy-Llaty Marion
Published: December 2021

Environmental health promotion interventions may reduce endocrine disruptor (ED) exposure. The PREVED (PREgnancy, preVention, Endocrine Disruptors) project was developed to improve knowledge, to enhance risk perception, and to change exposure behavior. Our objective was to present the phases of the PREVED project using the RE-AIM method. PREVED intervention consisted of three workshops during pregnancy. Reach, adoption, and implementation phases were assessed with qualitative studies. Efficacy study consisted of a three-arm randomized controlled trial (RCT) on 268 pregnant women: (i) control group (leaflet), (ii) intervention group in neutral location, (iii) intervention group in contextualized location. The main outcome was the percentage evolution of participants who reported consuming canned food. Secondary outcomes were evolution of psycho-social scores, evolution of ED presence in urine, and ED presence in colostrum. The intervention adoption was centered on upper-privileged women, but implementation assessment showed that key features (highly practical intervention) seemed to be carried out and had initiated some behavior changes. A total of 268 pregnant women participated in the intervention and 230 in a randomized controlled trial (control group: 86 and intervention groups: 172). We found no significant differences in consumption of canned food and in percentage of women having a decrease of bisphenol A or parabens in urine, but we found a significant increase in the evolution of risk perception score and overall psychosocial score in intervention groups (respectively: +15.73 control versus +21.03 intervention, p = 0.003 and +12.39 versus +16.20, p = 0.02). We found a significant difference in percentage of women with butylparaben detection between control group and intervention groups (13% versus 3%, p = 0.03). PREVED intervention is the first intervention research dedicated to perinatal environmental health education in France. By sharing know-how/experience in a positive non-alarmist approach, it improved risk perception, which is key to behavior change, aiming to reduce perinatal ED exposure. Including women in precarious situations remains a major issue.
Evaluation and Optimization of Walkability of Children’s School Travel Road for Accessibility and Safety Improvement
Authors: Zhao Jia , Su Wei , Luo Jiancheng , Zuo Jin
Published: December 2021

(1) Background: In the context of a children friendly city, accessibility and safety are the basic needs of children’s pedestrian school travel. This study proposes a comprehensive evaluation method of pedestrian accessibility and safety for children’s school travel. (2) Methods: Firstly, the school travel network was constructed by simulating the path of children walking to school. Secondly, from the meso and micro dimensions, the impact factors of pedestrian accessibility and safety were combed out, and an evaluation index system was constructed. Finally, pedestrian accessibility and safety were evaluated based on the Space Syntax analysis and ArcGIS spatial analysis, and the results were superimposed and spatially differentiated. The new evaluation method was tested in the Jintang Road area in Hedong District, Tianjin, China. (3) Results: The pedestrian accessibility and safety of children’s school travel road in the study area needed to be improved. It was found that the main impact factors were the effective walking width, the spatial connectivity, the visual integration, the obstruction of pedestrian safety, the completeness of crossing facilities and the influence of traffic flow and put forward optimization strategies. After optimized simulation verification, the overall improvement was achieved. (4) Conclusion: The evaluation method is helpful to calculate the pedestrian accessibility and safety of children’s school travel, and help decision makers determine the design and management strategies of child-friendly streets.
Outcome of Surgical Treated Isolated Pronator Teres Syndromes—A Retrospective Cohort Study and Complete Review of the Literature
Authors: Binder Harald , Zadra Armin , Popp Domenik , Komjati Micha , Tiefenboeck Thomas M.
Published: December 2021

Purpose: This study aims to elucidate the occurrence of postoperative carpal tunnel syndrome (CTS), the functional outcome of patients with primary pronator teres syndrome (PTS), and review complete literature regarding this topic. Material and Methods: A retrospective chart review was conducted in patients with PTS at a single center. In all patients, a numeric Visual Analog Scale (VAS) score, Pinch-Test, Jamar hand dynamometer test (JAMAR), and the Disabilities of the Arm Shoulder and Hand (DASH) score were analyzed preoperatively and at final follow-up to assess outcome. Additionally, a complete review of the literature was performed, including all data dealing with pronator teres syndrome. Results: Ten female and two male patients were included with a mean age of 49 years. Significant improvement in DASH and numeric VAS was detected at latest postoperative follow-up. In three patients, clinical signs of CTS pathology were detected during the follow-up period. One patient needed to be treated surgically, and in the other two patients, a conservative management was possible. In one patient (8%), a PTS recurrence was detected. All patients presented satisfied at latest follow-up. Conclusion: In one-fourth of our patients, a CTS occurred during the follow-up period. Therefore, focusing on double-crush syndrome in unclear or mixed symptoms is necessary to avoid multiple operations. Furthermore, it seems that assessment with NCV is not enough for diagnosing PTS; therefore, further research is needed to clarify this problem.
Impact of Service Quality of Low-Cost Carriers on Airline Image and Consumers’ Satisfaction and Loyalty during the COVID-19 Outbreak
Authors: Hassan Thowayeb H. , Salem Amany E.
Published: December 2021

Low-cost carriers (LCCs) in Saudi Arabia operate in a competitive, highly demanding environment. Customer-related attributes may be influenced by the levels of service quality in a no-frills airline, which might impact satisfaction and loyalty. Given the unique traveler and market characteristics of the aviation sector in the kingdom, we sought to investigate the impact of service quality of LCCs on customer satisfaction and loyalty and the perceived airline image. A total of 299 passengers at two international airports were approached using a modified SERVQUAL scale. Results revealed that service quality was a significant predictor of customer satisfaction (β = 0.46, p < 0.0001), airline image (β = 0.55, p < 0.0001), and customer loyalty (β = 0.16, p = 0.006). The responsiveness dimension was the most important dimension of service quality, since it predicted all other constructs (satisfaction, loyalty, and brand image). Airline tangibles and reliability were independently associated with brand image and loyalty, respectively. Based on these results, LCCs should tailor future strategic plans that rely heavily on improving different service quality measures, particularly the responsiveness domain.
Geospatial Distributions of Lead Levels Found in Human Hair and Preterm Birth in San Francisco Neighborhoods
Authors: Okorie Chinomnso N. , Thomas Marilyn D. , Méndez Rebecca M. , Di Giuseppe Erendira C. , Roberts Nina S. , Márquez-Magaña Leticia
Published: December 2021

In San Francisco (SF), many environmental factors drive the unequal burden of preterm birth outcomes for communities of color. Here, we examine the association between human exposure to lead (Pb) and preterm birth (PTB) in 19 racially diverse SF zip codes. Pb concentrations were measured in 109 hair samples donated by 72 salons and barbershops in 2018–2019. Multi-method data collection included randomly selecting hair salons stratified by zip code, administering demographic surveys, and measuring Pb in hair samples as a biomarker of environmental exposure to heavy metals. Concentrations of Pb were measured by atomic emission spectrometry. Aggregate neighborhood Pb levels were linked to PTB and demographic data using STATA 16 SE (StataCorp LLC, College Station, TX, USA). Pb varied by zip code (p < 0.001) and correlated with PTB (p < 0.01). Increases in unadjusted Pb concentration predicted an increase in PTB (β = 0.003; p < 0.001) and after adjusting for poverty (β = 0.002; p < 0.001). Confidence intervals contained the null after further adjustment for African American/Black population density (p = 0.16), suggesting that race is more indicative of high rates of PTB than poverty. In conclusion, Pb was found in every hair sample collected from SF neighborhoods. The highest concentrations were found in predominately African American/Black and high poverty neighborhoods, necessitating public health guidelines to eliminate this environmental injustice.
Neuroprotective Effect of Valproic Acid on Salicylate-Induced Tinnitus
Authors: Song Anji , Cho Gwang-Won , Vijayakumar Karthikeyan A. , Moon Changjong , Ang Mary Jasmin , Kim Jahae , Park Ilyong , Jang Chul Ho
Published: December 2021

High-dose salicylate induces temporary moderate hearing loss and the perception of a high-pitched tinnitus in humans and animals. Previous studies demonstrated that high doses of salicylate increase N-methyl-d-aspartate (NMDA) receptor levels, resulting in a rise in Ca2+ influx and induction of excitotoxicity. Glutamate excitotoxicity is associated with failure in the maintenance of calcium homeostasis, mitochondrial dysfunction, and production of reactive oxygen species (ROS). Valproic acid (VPA) is widely used for the management of bipolar disorder, epilepsy, and migraine headaches, and is known to regulate NMDA receptor activity. In this study, we examined the beneficial effects of VPA in a salicylate-induced tinnitus model in vitro and in vivo. Cells were pretreated with VPA followed by salicylate treatment. The expression levels of NMDA receptor subunit NR2B, phosphorylated cAMP response element-binding protein—an apoptosis marker, and intracellular levels of ROS were measured using several biochemical techniques. We observed increased expression of NR2B and its related genes TNFα and ARC, increased intracellular ROS levels, and induced expression of cleaved caspase-3. These salicylate-induced changes were attenuated in the neuronal cell line SH-SY5Y and rat cortical neurons after VPA pretreatment. Together, these results provide evidence of the beneficial effects of VPA in a salicylate-induced temporary hearing loss and tinnitus model.
Environmental Factors That Affect Parathyroid Hormone and Calcitonin Levels
Authors: Babić Leko Mirjana , Pleić Nikolina , Gunjača Ivana , Zemunik Tatijana
Published: December 2021

Calciotropic hormones, parathyroid hormone (PTH) and calcitonin are involved in the regulation of bone mineral metabolism and maintenance of calcium and phosphate homeostasis in the body. Therefore, an understanding of environmental and genetic factors influencing PTH and calcitonin levels is crucial. Genetic factors are estimated to account for 60% of variations in PTH levels, while the genetic background of interindividual calcitonin variations has not yet been studied. In this review, we analyzed the literature discussing the influence of environmental factors (lifestyle factors and pollutants) on PTH and calcitonin levels. Among lifestyle factors, smoking, body mass index (BMI), diet, alcohol, and exercise were analyzed; among pollutants, heavy metals and chemicals were analyzed. Lifestyle factors that showed the clearest association with PTH levels were smoking, BMI, exercise, and micronutrients taken from the diet (vitamin D and calcium). Smoking, vitamin D, and calcium intake led to a decrease in PTH levels, while higher BMI and exercise led to an increase in PTH levels. In terms of pollutants, exposure to cadmium led to a decrease in PTH levels, while exposure to lead increased PTH levels. Several studies have investigated the effect of chemicals on PTH levels in humans. Compared to PTH studies, a smaller number of studies analyzed the influence of environmental factors on calcitonin levels, which gives great variability in results. Only a few studies have analyzed the influence of pollutants on calcitonin levels in humans. The lifestyle factor with the clearest relationship with calcitonin was smoking (smokers had increased calcitonin levels). Given the importance of PTH and calcitonin in maintaining calcium and phosphate homeostasis and bone mineral metabolism, additional studies on the influence of environmental factors that could affect PTH and calcitonin levels are crucial.