bluuebunny/crossref_metadata_2025 huggingface dataset:
Impaired effective functional connectivity in the social preference of children with autism spectrum disorder
Authors: Deng Simin , Tan Si , Guo Cuihua , Liu Yanxiong , Li Xiuhong
Published: May 2024

Background

The medial prefrontal cortex (mPFC), amygdala (Amyg), and nucleus accumbens (NAc) have been identified as critical players in the social preference of individuals with ASD. However, the specific pathophysiological mechanisms underlying this role requires further clarification. In the current study, we applied Granger Causality Analysis (GCA) to investigate the neural connectivity of these three brain regions of interest (ROIs) in patients with ASD, aiming to elucidate their associations with clinical features of the disorder.

Methods

Resting-state functional magnetic resonance imaging (rs-fMRI) data were acquired from the ABIDE II database, which included 37 patients with ASD and 50 typically developing (TD) controls. The mPFC, Amyg, and NAc were defined as ROIs, and the differences in fractional amplitude of low-frequency fluctuations (fALFF) within the ROIs between the ASD and TD groups were computed. Subsequently, we employed GCA to investigate the bidirectional effective connectivity between the ROIs and the rest of the brain. Finally, we explored whether this effective connectivity was associated with the social responsiveness scale (SRS) scores of children with ASD.

Results

The fALFF values in the ROIs were reduced in children with ASD when compared to the TD group. In terms of the efferent connectivity from the ROIs to the whole brain, the ASD group exhibited increased connectivity in the right cingulate gyrus and decreased connectivity in the right superior temporal gyrus. Regarding the afferent connectivity from the whole brain to the ROIs, the ASD group displayed increased connectivity in the right globus pallidus and decreased connectivity in the right cerebellar Crus 1 area and left cingulate gyrus. Additionally, we demonstrated a positive correlation between effective connectivity derived from GCA and SRS scores.

Conclusion

Impairments in social preference ASD children is linked to impaired effective connectivity in brain regions associated with social cognition, emotional responses, social rewards, and social decision-making. This finding further reveals the potential neuropathological mechanisms underlying ASD.
Multivariate-coupling LOCA prediction using zLSTM
Authors: Li Xichen , Chen Xiang , She Jingke , Zhang Yifan , Wang Taizhe
Published: May 2024

A novel deep learning model zLSTM, which evolves from Long-Short Term Memory (LSTM) with enhanced long-term processing capability, is applied to the prediction of Loss of Coolant Accident (LOCA). During the prediction process, six-dimensional multivariate coupling is established among six major system parameters after connecting each timestep with the time dimension. The demonstration experiments show that the proposed method can increase the prediction accuracy by 35.84% comparing to the traditional LSTM baseline. Furthermore, zLSTM model follows the parameter progress well at the starting stage of LOCA, which reduces the prediction error at both the beginning and the far end.
Causal effects of dietary composition on multiple sclerosis risk and severity: a Mendelian randomization study
Authors: Nan Haitian
Published: May 2024

Objectives

Observational studies have found potential associations between dietary intake and multiple sclerosis (MS). However, these associations are inconsistent, and the causal relationship remains unclear. In this study, we aim to examine the causal relationship between genetically predicted dietary composition and the risk and severity of MS using two-sample Mendelian randomization.

Method

Genetic instruments for 30 different dietary compositions were extracted from large-scale genome-wide association studies (GWAS), mainly from the UK Biobank dataset. The GWAS data for MS risk and severity were obtained from the International Multiple Sclerosis Genetics Consortium. The primary analysis employed either the inverse variance weighted method or the Wald ratio method to evaluate the causal association. Several sensitivity analyses were also performed.

Results

Genetically predicted higher pork intake was causally associated with an increased risk of MS (odds ratio [OR] = 6.76; p = 0.005), while genetically driven higher cereal intake (OR = 0.43, p = 0.016), vitamin C supplement (OR < 0.01; p = 4.34 × 10−5), folic acid supplement (OR < 0.01; p = 4.91 × 10−71), and fish oil supplement (OR = 0.04; p = 0.017) were causally linked to a decreased risk of MS. In addition, genetically predicted higher alcoholic intake (OR = 1.17; p = 0.041) was causally associated with an increase in MS severity, while folic acid supplement (OR < 0.01; p = 0.015) was causally linked to a decrease in MS severity.

Interpretation

This study found that increased consumption of cereal, vitamin C, folic acid, and fish oil, coupled with reduced pork and alcohol intake, may potentially decrease the risk and severity of MS. These findings inform the development of dietary-based strategies for MS prevention and treatment.
Middle ear neuroendocrine tumor with multiple brain metastases: a case report and literature review
Authors: Sun Yesheng , Zhang Ying , Cai Dongpeng , Zhang Wei , Yang Zhiqian
Published: May 2024

Middle ear neuroendocrine tumor (MeNET) is a low-grade tumor with rare recurrence or metastasis. Here, we describe the case of a 29-year-old man who suffered from MeNET that recurred 3 times over 10 years and eventually metastasized to the brain. The patient was treated with surgical resection, radiotherapy, and chemotherapy. However, the tumor was not entirely removed as the brain metastatic tumor adhered tightly to the brainstem. Due to tumor rupture and bleeding after multiple brain tumor removal, profound coma developed. Finally, the patient died 10 months after the last surgery. To our knowledge, this is the first report of a MeNET case with multiple brain metastases. Characteristics of the present case indicate that CK, SYN, increased Ki67 index, and ATRX may be potential biomarkers of invasive MeNET. The survival of patients with brain metastatic MeNET may be extended by surgical resection, radiotherapy, and chemotherapy. Close follow-up of distinctive metastases and biomarkers related to recurrence is also suggested.
Pharmacological mTOR inhibitors in ameliorating Alzheimer’s disease: current review and perspectives
Authors: Xie Pei-Lun , Zheng Meng-Yu , Han Ran , Chen Wei-Xin , Mao Jin-Hua
Published: May 2024

Traditionally, pharmacological mammalian/mechanistic targets of rapamycin (mTOR) kinase inhibitors have been used during transplantation and tumor treatment. Emerging pre-clinical evidence from the last decade displayed the surprising effectiveness of mTOR inhibitors in ameliorating Alzheimer’s Disease (AD), a common neurodegenerative disorder characterized by progressive cognitive function decline and memory loss. Research shows mTOR activation as an early event in AD development, and inhibiting mTOR may promote the resolution of many hallmarks of Alzheimer’s. Aberrant protein aggregation, including amyloid-beta (Aβ) deposition and tau filaments, and cognitive defects, are reversed upon mTOR inhibition. A closer inspection of the evidence highlighted a temporal dependence and a hallmark-specific nature of such beneficial effects. Time of administration relative to disease progression, and a maintenance of a functional lysosomal system, could modulate its effectiveness. Moreover, mTOR inhibition also exerts distinct effects between neurons, glial cells, and endothelial cells. Different pharmacological properties of the inhibitors also produce different effects based on different blood-brain barrier (BBB) entry capacities and mTOR inhibition sites. This questions the effectiveness of mTOR inhibition as a viable AD intervention strategy. In this review, we first summarize the different mTOR inhibitors available and their characteristics. We then comprehensively update and discuss the pre-clinical results of mTOR inhibition to resolve many of the hallmarks of AD. Key pathologies discussed include Aβ deposition, tauopathies, aberrant neuroinflammation, and neurovascular system breakdowns.
Bi-specific T-cell engagers (BiTEs) in prostate cancer and strategies to enhance development: hope for a BiTE-r future
Authors: Lampe Harriet , Tam Laura , Hansen Aaron R.
Published: May 2024

Metastatic castrate resistant prostate cancer (mCRPC) continues to have poor survival rates due to limited treatment options. Bi-specific T cell engagers (BiTEs) are a promising class of novel immunotherapies with demonstrated success in haematological malignancies and melanoma. BiTEs developed for tumour associated antigens in prostate cancer have entered clinical testing. These trials have been hampered by high rates of treatment related adverse events, minimal or transient anti-tumour efficacy and generation of high titres of anti-drug antibodies. This paper aims to analyse the challenges faced by the different BiTE therapy constructs and the mCRPC tumour microenvironment that result in therapeutic resistance and identify possible strategies to overcome these issues.
Investigating the exotic magnetic properties in manganese diboride, a borophene intercalation compound
Authors: Li Hui , Cui Siwen , Huang Yi , Zhao Yongsheng , Zhu Pinwen , Ma Shuailing
Published: May 2024

The temperature-dependent magnetic susceptibility combined with first-principle calculations was conducted to unravel the magnetic structure and the magnetic interaction of the laminar structure of manganese diboride (MnB2). MnB2 showed weak ferromagnetic, antiferromagnetic, and paramagnetic behavior with increased temperature. Its weak ferromagnetic property below 135.6 K Curie temperature (TC) originated from the spin canting antiferromagnetic magnetic structure. The exotic kink of temperature-dependent magnetic susceptibility at 330 K Néel temperature (TN) correlated with the transition from antiferromagnetic to paramagnetic structure. First-principle calculation show that the antiferromagnetic ordering show lower energy, and suggest a canting anti-ferromagnetic ordering for its ferromagnetic behavior. The peculiar magnetic behavior of MnB2 may be due to the insertion of the honeycomb boron layers into the host matrix of manganese atoms. The honeycomb boron layers played a key role in the exchange between two manganese layers. This study resolved the longstanding puzzle of the magnetic structure of MnB2 and provided a typical laminar magnetic structure prototype.
Filament simulations for stellarators; a review of recent progress
Authors: Shanahan Brendan
Published: May 2024

A review of recent advances in simulations of turbulent filaments with relevance to stellarators is presented. Progress in performing global edge turbulence simulations is discussed as well as results from seeded filament simulations with applications to the unique environment of a stellarator island divertor–including abrupt changes in connection length and highly-nonuniform curvature drive. It is determined that the motion of filaments generally follows the average curvature, but strong nonuniform perturbations can shear a filament and reduce the overall transport. The coherence of filament transport is also determined to be influenced by the collisionality and electron plasma beta. By simplifying the simulation geometries, large parameter scans can be performed which accurately reflect the macroscopic transport of filaments observed in Wendelstein 7-X. Comparisons to experiments are discussed, and a the develeopment of a synthetic diagnostic has been able to inform experimental measurements by quantifying potential sources of error in filament propagation measurements. A discussion of the necessary extension to more complex multifluid models, and the scope for near-term filament simulations in stellarators, is provided.
The biology of Marchantia polymorpha subsp. ruderalis Bischl. & Boissel. Dub in nature
Authors: Duckett Jeffrey G. , Pressel Silvia , Kowal Jill
Published: May 2024

Introduction

Though used as the model liverwort in culture for several decades, the biology of Marchantia polymorpha subsp. ruderalis in nature has never been documented in detail in a single account.

Methods

Here we synthesize routine field observations documented with hundreds of images of M. ruderalis colonies (or groups) showing sex differentiation over 3 years on two populations of M. ruderalis after major heathland fires in 2020.

Results

Initial post-fire establishment is from airborne spores rather than a spore bank but thereafter spread is via gemmae which have less exacting germination requirements. Young sporelings are highly gemmiferous but gemmae production becomes less frequent after sex organ formation. Over the course of a year there are up to three waves of carpocephalum production with the overwhelming majority of antheridiophores appearing 2-3 months ahead of the archegoniophores though no differences in growth rates were apparent between male and female thalli. Spermatozoids are produced almost continuously throughout the year, whilst sporophyte maturation is restricted to the summer months.

Discussion

Because of the asynchrony between antheridiophore and archegoniophore production a 1:1 sex ratio is only apparent over this period. The spring months see an excess of males with more females in the summer. An almost 100% fertilization rate, with fertilization distances of up to 19 m far exceeding those in all other bryophytes, is attributed to vast spermatozoid production for most of the year, dispersal on surface oil films between thalli and highly effective intra-thallus spermatozoid transport via the pegged-rhizoid water-conducting system. Archegoniophores do develop on female-only populations but have shorter stalks than those where fertilization has occurred. Eventual disappearance post fires is attributed to a fall in topsoil nutrient levels preventing new sporeling establishment and competition from Ceratodon purpureus and Polytrichum spp. A major drought in the summer of 2022 almost wiped out the heathland Marchantia populations but all the other bryophytes survived.
Research on non-destructive and rapid detection technology of foxtail millet moisture content based on capacitance method and Logistic-SSA-ELM modelling
Authors: Qiu Zhichao , Li Gangao , Huang Zongbao , He Xiuhan , Zhang Zilin , Li Zhiwei , Du Huiling
Published: May 2024

Moisture content testing of agricultural products is critical for quality control, processing efficiency and storage management. Testing foxtail millet moisture content ensures stable foxtail millet quality and helps farmers determine the best time to harvest. A differential capacitance moisture content detection device was designed based on STM32 and PCAP01 capacitance digital converter chip. The capacitance method combined with the back-propagation(BP) algorithm and the extreme learning machine(ELM) algorithm was chosen to construct an analytical model for foxtail millet moisture content, temperature, and volume duty cycle. This work performs capacitance measurements on foxtail millet with different moisture contents, temperatures, and proportions of the measured substance occupying the detection area (that is, the volumetric duty cycle). On this foundation, the sparrow search algorithm (SSA) is used to optimize the BP and ELM models. However, SSA may encounter problems such as falling into local optimization solutions due to the reduction of population diversity in the late iterations. As a consequence, Logistic algorithm is introduced to optimize SSA, making it more appropriate for solving specific problems. Upon comparative analysis, the model predicted using the Logistic-SSA-ELM algorithm was more accurate. The results indicate that the predicted values of prediction set coefficient of determination (RP), prediction set root mean square error (RMSEP) and prediction set ratio performance deviation (RPDP) were 0.7016, 3.7150 and 1.4035, respectively. This algorithm has excellent prediction performance and can be used as a model for detection of foxtail millet moisture content. In view of the important role of foxtail millet moisture content detection in acquisition and storage, it is particularly important to study a nondestructive and fast online real-time detection method. The designed capacitive sensor with differential structure has well stabilization and high accuracy, which can be further studied in depth and gradually move towards the general trend of agricultural development of smart agriculture and precision agriculture.
Development of self-compatible Chinese cabbage lines of Chiifu through marker-assisted selection
Authors: Chang Lichun , Liang Jianli , Cai Xu , Zhang Li , Li Yufang , Wu Jian , Wang Xiaowu
Published: May 2024

The continuously refined genome assembly of the Chinese cabbage accession Chiifu is widely recognized as the reference for Brassica rapa. However, the high self-incompatibility of Chiifu limits its broader utilization. In this study, we report the development of self-compatible Chiifu lines through a meticulous marker-assisted selection (MAS) strategy, involving the substitution of the Chiifu allele of MLPK (M-locus protein kinase) with that from the self-compatible Yellow Sarson (YS). A YS-based marker (SC-MLPK) was employed to screen 841 B. rapa accessions, confirming that all eight accessions with the mlpk/mlpk (mm) genotype exhibited self-compatibility. Additionally, we designed 131 High-Resolution Melting (HRM) markers evenly distributed across the B. rapa genome as genomic background selection (GBS) markers to facilitate the introgression of self-compatibility from YS into Chiifu along with SC-MLPK. Genome background screening revealed that the BC3S1 population had a proportion of the recurrent parent genome (PR) ranging from 93.9% to 98.5%. From this population, we identified self-compatible individuals exhibiting a high number of pollen tubes penetrating stigmas (NPT) (>25) and a maximum compatibility index (CI) value of 7.5. Furthermore, we selected two individuals demonstrating significant similarity to Chiifu in both genetic background and morphological appearance, alongside self-compatibility. These selected individuals were self-pollinated to generate two novel lines designated as SC-Chiifu Lines. The development of these self-compatible Chiifu lines, together with the SC-MLPK marker and the set of HRM markers, represents valuable tools for B. rapa genetics and breeding.
Research on drought stress in Medicago sativa L. from 1998 to 2023: a bibliometric analysis
Authors: Zhou Zijun , Li Junqin , Gao Yang , Wang Xiangtao , Wang Rui , Huang Haiyan , Zhang Yu , Zhao Lili , Wang Puchang
Published: May 2024

Alfalfa (Medicago sativa L.) is one of the most important forage crops in the world. Drought is recognized as a major challenge limiting alfalfa production and threatening food security. Although some literature reviews have been conducted in this area, bibliometric reviews based on large amounts of published data are still lacking. In this paper, a bibliometric analysis of alfalfa drought stress from 1998–2023 was conducted using the Web of Science Core Collection database in order to assess global trends in alfalfa drought stress research and to provide new directions for future research. The results showed that the annual publication output maintained an increase in most years, with China and the United States contributing significantly to the field. Most of the journals published are specialized journals in botany, environmental science, soil science and crop science, as well as related agribusiness journals. “plant growth” and “yield” were the most frequently used keywords, reflecting the important purpose of research in this field. And two main research directions were identified: research on drought response mechanism of alfalfa and exploration of drought-resistant technology. In addition, physiological, biochemical, and molecular responses of drought tolerance and high yield in alfalfa, transgenics, and microbial fertilizer research have been hot research topics in recent years and may continue in the future. The ultimate goal of this paper is to provide a foundational reference for future research on alfalfa’s drought resistance and yield optimization mechanisms, thereby enhancing the crop’s application in agricultural production.
Nutrient enrichment, propagule pressure, and herbivory interactively influence the competitive ability of an invasive alien macrophyte Myriophyllum aquaticum
Authors: Huang Ru , Oduor Ayub M. O. , Yan Yimin , Yu Weicheng , Chao Chuanxin , Dong Lei , Jin Shaofei , Li Feng
Published: May 2024

Introduction

Freshwater ecosystems are susceptible to invasion by alien macrophytes due to their connectivity and various plant dispersal vectors. These ecosystems often experience anthropogenic nutrient enrichment, favouring invasive species that efficiently exploit these resources. Propagule pressure (reflecting the quantity of introduced individuals) and habitat invasibility are key determinants of invasion success. Moreover, the enemy release hypothesis predicts that escape from natural enemies, such as herbivores, allows alien species to invest more resources to growth and reproduction rather than defense, enhancing their invasive potential. Yet, the combined impact of propagule pressure, herbivory, and nutrient enrichment on the competitive dynamics between invasive alien macrophytes and native macrophyte communities is not well understood due to a paucity of studies.

Methods

We conducted a full factorial mesocosm experiment to explore the individual and combined effects of herbivory, nutrient levels, propagule pressure, and competition on the invasion success of the alien macrophyte Myriophyllum aquaticum into a native macrophyte community comprising Vallisneria natans, Hydrilla verticillata, and Myriophyllum spicatum. This setup included varying M. aquaticum densities (low vs. high, simulating low and high propagule pressures), two levels of herbivory by the native snail Lymnaea stagnalis (herbivory vs no-herbivory), and two nutrient conditions (low vs. high). Myriophyllum aquaticum was also grown separately at both densities without competition from native macrophytes.

Results

The invasive alien macrophyte M. aquaticum produced the highest shoot and total biomass when simultaneously subjected to conditions of high-density intraspecific competition, no herbivory, and low-nutrient availability treatments. Moreover, a high propagule pressure of M. aquaticum significantly reduced the growth of the native macrophyte community in nutrient-rich conditions, but this effect was not observed in nutrient-poor conditions.

Discussion

These findings indicate that M. aquaticum has adaptive traits enabling it to flourish in the absence of herbivory (supporting the enemy release hypothesis) and in challenging environments such as intense intraspecific competition and low nutrient availability. Additionally, the findings demonstrate that when present in large numbers, M. aquaticum can significantly inhibit the growth of native macrophyte communities, particularly in nutrient-rich environments. Consequently, reducing the propagule pressure of M. aquaticum could help control its spread and mitigate its ecological impact. Overall, these findings emphasize that the growth and impacts of invasive alien plants can vary across different habitat conditions and is shaped by the interplay of biotic and abiotic factors.
Patterns of occupational commitment among nurses: a latent profile analysis
Authors: Lin Zihan , Wu Wenbin , Zhang Huifang , He Zhiqiang , Han Mengyu , Li Jin
Published: May 2024

Background

Occupational commitment (OC) is a multidimensional construct that predicts turnover intentions. The interindividual variability of nurses’ OC merits further exploration. Therefore, this study aims to examine patterns of OC and its relationship with psychological empowerment and job crafting in nurses.

Methods

A sample of 1,061 nurses was recruited from February 2022 to April 2022 by using a stratified four-stage cluster sampling procedure. A self-report survey included the Psychological Empowerment Scale, Job Crafting Scale, and Occupational Commitment Scale. Latent profile analysis (LPA) was used to examine the patterns of OC. Associations of the latent class membership with individual characteristics, psychological empowerment and job crafting were examined using multinomial logistic regression.

Results

Three patterns of OC were identified: (1) “Low OC group” (n = 224, 21.1%); (2) “Moderate OC group” (n = 665, 62.7%); (3) “High OC group” (n = 172, 16.2%). Nurses with higher education, fewer years of service, working in medicine, lower psychological empowerment and lower job crafting had a higher likelihood of belonging to Class 1 (Low OC group). In contrast, nurses working in emergency and with higher psychological empowerment and job crafting were more likely to belong to Class 3 (High OC group).

Conclusion

The findings revealed the heterogeneity of occupational commitment among nurses in China and could guide the identification and early intervention of nurses with low level of occupational commitment.
Coping methods of college students with different personality traits when facing COVID-19 from the anxiety psychology perspective
Authors: Fu Hai , Mao Yuyao , Tian Li
Published: May 2024

Objective

Based on a survey of anxiety among college students during the epidemic, this study takes anxiety as an example to study the coping methods of college students with different personality traits. Thus predicting the behavioral tendencies of college students and proposing some appropriate suggestions for the current psychological education work of college students. Method: The study was carried out during the large-scale outbreak of the COVID-19 epidemic, and the investigation lasted one month. Using the Self Rating Anxiety Scale (SAS), Eysenck Personality Questionnaire Simplified Chinese Version (EPQ-RSC), and Trait Coping Style Scale (TCSQ), an online questionnaire survey was conducted on 932 college students to analyze the mutual effects of different grades, genders, personality traits, coping methods, and other factors.

Results

The research found that there was a significant gender difference in negative coping methods and anxiety among college students. Grade differences: In the comparative study of personality traits, there are gender differences in introversion and concealment dimensions and grade differences in neuroticism and concealment dimensions. There is a pairwise correlation between personality traits, coping methods, and anxiety. There is a significant positive correlation between the dimensions of psychoticism, neuroticism and anxiety; There is a significant negative correlation between introversion, concealment, and anxiety. Positive coping methods are significantly negatively correlated with anxiety, while negative coping methods are significantly positively correlated with anxiety. The positive coping style is significantly negatively correlated with the dimensions of psychoticism and neuroticism and positively correlated with the dimensions of introversion, introversion, and concealment; Negative coping methods are significantly positively correlated with the dimensions of psychoticism and neuroticism and negatively correlated with the dimensions of introversion, introversion, and concealment.

Conclusion

The research results indicate that the mental health issues of college students need to be taken seriously to prevent the spread of anxiety.
Rearticulating the promotion of Japanese language and culture from the perspective of “soft power”: planning and effects
Authors: Gu Jingshu , Deng Shiping
Published: May 2024

The concept of soft power has engendered lively discourse within the international community. The development of a nation’s soft power frequently hinges on cultural communication and the promotion of language. This manuscript concentrates on Japan as a case study and undertakes an investigation of the methods it has employed to cultivate its soft power. To accomplish this objective, Japan’s strategies for cultural communication and the promotion of the Japanese language are comprehensively examined. From the perspective of language planning, prestige planning of language and culture constitutes a crucial mode of cultural communication, whereas language education planning (or acquisition planning) is the primary method of language promotion. Japan has adeptly disseminated its culture overseas through cultural communication and language promotion. On one hand, it fashions a “cool culture” embodied by anime and manga to augment cultural appeal and amplify national image. On the other hand, it advances the Japanese language abroad by establishing supportive institutions, dispatching experts and volunteers, and creating online teaching materials. Building on Japan, this paper establishes a theoretical framework for the construction of soft power, employing the aforementioned two approaches as valuable guides for research on soft power.
Young users of social media: an analysis from a gender perspective
Authors: Aran-Ramspott Sue , Korres-Alonso Oihane , Elexpuru-Albizuri Iciar , Moro-Inchaurtieta Álvaro , Bergillos-García Ignacio
Published: May 2024

One of the major challenges for edu-communication research is to analyze the influence of social media on young and adolescent users. This article examines the evaluation of gender inequalities – real and symbolic – in the consumption of social networks such as YouTube and Instagram among young people. Within the framework of a Research & Development & innovation (R&D + i) project, it presents a discursive-theoretical analysis of how young users of social media perceive the presence and representation of gender on social media and whether such digital representations can be associated with an empowering gender perspective. This study presents results from 14 focus groups (N = 83), composed of students aged 12 to 18, drawn from three Spanish Autonomous Communities (Catalonia, the Balearic Islands and the Basque Country). The results show that gender issues arise in participants’ conversations, especially among female participants, who perceive the importance of physical appearance on platforms such as Instagram and TikTok. Female participants feel more pressure in terms of appearance and dress compared to male participants. Among male participants there are more expressions of self-affirmation and more mentions related to fun and social prestige. Both male and female participants express concern about the impact of that pressure on younger girls. The influence of social media on self-image is more evident among female participants, who make frequent mention of the importance of self-esteem in relation to beauty standards and exposure to idealized body images. Notably, there were no comments by male participants that acknowledge any influence of social media on their self-image. The findings are in line with existing research and taken as a whole gives rise to concern as to the gender disparities observed in the use of social media, which do not constitute a picture of female empowerment. This research underlines the importance of promoting a respectful and equitable environment in relation to gender equality within digital spaces. Thus, this study provides support for the need to develop and implement edu-communicative initiatives to foster critical thinking around the influence of social media in this context and the evaluation of the impact of such initiatives in future research.
Antecedents of innovative behavior in public organizations: the role of public service motivation, organizational commitment, and perceived innovative culture
Authors: Lee Geon , Kim Chulwoo
Published: May 2024

Introduction

This study examines the dynamics of public service motivation (PSM), organizational commitment, and perceived innovative culture and their collective influence on innovative behavior in public organizations. It uniquely focuses on intrinsic motivational factors, extends the scope of motivational studies to the public sector, and highlights the crucial role of organizational culture in fostering innovation.

Methods

A web-based survey was administered to 1,021 public servants in the central government of the Republic of Korea. Structured questionnaires were used to collect data, and structural equation modeling (SEM) was employed to analyze the relationships between the variables.

Results

The SEM results confirmed positive correlations between PSM and both organizational commitment and innovative behavior. However, contrary to expectations, organizational commitment did not significantly predict innovative behavior. Additionally, no mediating effect of organizational commitment was observed. Notably, perceived innovative culture was found to moderate the relationship between PSM and organizational commitment, and between organizational commitment and innovative behavior, particularly in environments with a strong innovation focus.

Discussion

These findings underscore the significance of PSM in spurring innovative behavior in the public sector, broadening our understanding of intrinsic motivation. This study also accentuates the influence of organizational culture on these dynamics. In practical terms, this suggests the importance of nurturing individuals with high PSM and fostering an environment that balances perceived innovative culture. While contributing to the fields of organizational psychology and public administration, this study has certain limitations and indicates the need for further research in various contexts.
Mental health and conflict: a pilot of an online eye movement desensitisation and reprocessing (EMDR) intervention for forcibly displaced Syrian women
Authors: Hamid Aseel , Williams Amanda C. de C. , Albakri Muslihah , Scior Katrina , Morgan Sian , Kayal Hamodi , Wilcockson Matthew , Drouish Alkaja Rouba , Alsayed Sahbaa , Logie Robin , Farrand Shiraz , Abdul-Hamid Walid
Published: May 2024

Background

The Syrian conflict has been ongoing since 2011. Practical and scalable solutions are urgently needed to meet an increase in need for specialised psychological support for post-traumatic stress disorder given limited availability of clinicians. Training forcibly displaced Syrians with a mental health background to remotely deliver specialised interventions increases the availability of evidence based psychological support. Little is known about the effectiveness of online therapy for forcibly displaced Syrian women provided by forcibly displaced Syrian women therapists.

Purpose

To pilot an evidence-based trauma therapy, Eye Movement Desensitisation and Reprocessing (EMDR), carried out online by trained forcibly displaced Syrian women therapists for forcibly displaced Syrian women who require treatment for post-traumatic stress disorder (PTSD).

Methods

83 forcibly displaced Syrian women, living in Türkiye or inside Syria, with diagnosable PTSD, were offered up to 12 sessions of online EMDR over a period of 3 months. This was delivered by forcibly displaced Syrian women therapists who were trained in EMDR. Data were gathered, using Arabic versions, on PTSD symptoms using the Impact of Events Scale Revised, depression symptoms using the Patient Health Questionnaire-9 and anxiety symptoms using the Generalised Anxiety Disorder Assessment-7 at baseline, mid-point, and end of therapy.

Results

PTSD scores, depression scores and anxiety scores all significantly reduced over the course of treatment, with lower scores at midpoint than baseline and lower scores at end of treatment than at midpoint. Only one participant (1%) exceeded the cutoff point for PTSD, and 13 (16%) exceeded the cutoff points for anxiety and depression at the end of treatment.

Conclusion

In this pilot study up to 12 sessions of online EMDR were associated with reductions in PTSD, anxiety and depression symptoms in Syrian women affected by the Syrian conflict. The training of forcibly displaced Syrian mental health professionals to deliver online therapy is a relatively low cost, scalable, sustainable solution to ensure that those who are affected by the conflict can access specialised support. Further research is needed using a control group to confirm that the observed effects are due to EMDR treatment, as is research with post-treatment follow-up to ascertain that benefits are maintained.
Causal analysis of radiotherapy safety incidents based on a hybrid model of HFACS and Bayesian network
Authors: He Haiping , Peng Xudong , Luo Dashuang , Wei Weige , Li Jing , Wang Qiang , Xiao Qing , Li Guangjun , Bai Sen
Published: May 2024

Objective

This research investigates the role of human factors of all hierarchical levels in radiotherapy safety incidents and examines their interconnections.

Methods

Utilizing the human factor analysis and classification system (HFACS) and Bayesian network (BN) methodologies, we created a BN-HFACS model to comprehensively analyze human factors, integrating the hierarchical structure. We examined 81 radiotherapy incidents from the radiation oncology incident learning system (RO-ILS), conducting a qualitative analysis using HFACS. Subsequently, parametric learning was applied to the derived data, and the prior probabilities of human factors were calculated at each BN-HFACS model level. Finally, a sensitivity analysis was conducted to identify the human factors with the greatest influence on unsafe acts.

Results

The majority of safety incidents reported on RO-ILS were traced back to the treatment planning phase, with skill errors and habitual violations being the primary unsafe acts causing these incidents. The sensitivity analysis highlighted that the condition of the operators, personnel factors, and environmental factors significantly influenced the occurrence of incidents. Additionally, it underscored the importance of organizational climate and organizational process in triggering unsafe acts.

Conclusion

Our findings suggest a strong association between upper-level human factors and unsafe acts among radiotherapy incidents in RO-ILS. To enhance radiation therapy safety and reduce incidents, interventions targeting these key factors are recommended.
Long COVID awareness and receipt of medical care: a survey among populations at risk for disparities
Authors: Fisher Kimberly A. , Mazor Kathleen M. , Epstein Mara M. , Goldthwait Lydia , Abu Ghazaleh Hiba , Zhou Yanhua , Crawford Sybil , Marathe Jai , Linas Benjamin P.
Published: May 2024

Introduction

The COVID-19 pandemic has been characterized by disparities in disease burden and medical care provision. Whether these disparities extend to long COVID awareness and receipt of medical care is unknown. We aimed to characterize awareness of long COVID and receipt of medical care for long COVID symptoms among populations who experience disparities in the United States (US).

Methods

We conducted a cross-sectional survey among a national sample of US adults between January 26–February 5, 2023. We surveyed approximately 2,800 adults drawn from the Ipsos probability-based KnowledgePanel® who identify as White, Black, or Hispanic, with over-sampling of Black, Hispanic, and Spanish-proficient adults. Awareness of long COVID was assessed with the question, “Have you heard of long COVID? This is also referred to as post-COVID, Long-haul COVID, Post-acute COVID-19, or Chronic COVID.” Respondents reporting COVID-19 symptoms lasting longer than 1 month were classified as having long COVID and asked about receipt of medical care.

Results

Of the 2,828 respondents, the mean age was 50.4 years, 52.8% were female, 40.2% identified as Hispanic, 29.8% as Black, and 26.7% as White. 18% completed the survey in Spanish. Overall, 62.5% had heard of long COVID. On multivariate analysis, long COVID awareness was lower among respondents who identified as Black (OR 0.64; 95% CI 0.51, 0.81), Hispanic and completed the survey in English (OR 0.59; 95% CI 0.46, 0.76), and Hispanic and completed the survey in Spanish (OR 0.31, 95% C.I. 0.23, 0.41), compared to White respondents (overall p < 0.001). Long COVID awareness was also associated with educational attainment, higher income, having health insurance, prior history of COVID-19 infection, and COVID-19 vaccination. Among those reporting symptoms consistent with long COVID (n = 272), 26.8% received medical care. Older age, longer symptom duration and greater symptom impact were associated with receipt of medical care for long COVID symptoms. Of those who received care, most (77.8%) rated it as less than excellent on a 5-point scale.

Discussion

This survey reveals limited awareness of long COVID and marked disparities in awareness according to race, ethnicity, and language. Targeted public health campaigns are needed to raise awareness.
Affiliate Stigma among family caregivers of individuals with dementia in China: a cross-sectional study
Authors: Shi Yingying , Dong Shishi , Liang Zhiqi , Xie Mengting , Zhang Hanyi , Li Sixie , Li Jufang
Published: May 2024

Background

Affiliate stigma experienced by family caregivers of individuals with dementia may seriously affect home care and prognosis of these patients. This study aimed to explore the levels of perceived affiliate stigma and its influencing factors among family caregivers of patients with dementia in mainland China, which remains a relatively unexplored topic.

Methods

In this cross-sectional study, purposive sampling was used to recruit dementia family caregivers from an online communication group between April and May 2022. A total of 727 eligible caregivers were included and asked to complete the demographic questionnaire, the affiliate stigma scale, and the caregiver burden inventory. Descriptive statistics, independent sample t-test, one-way analysis of variance, Pearson correlation analysis, and multiple linear regression were used to explore the factors that influence perceived affiliate stigma among dementia family caregivers.

Results

The mean score for affiliate stigma of dementia family caregivers was 48.09 ± 16.38 (range: 22–86). Whether there were regular breaks during patient care, time-dependent burden, developmental burden, physical burden, and social burden were significant factors influencing the affiliate stigma of dementia family caregivers.

Conclusion

Dementia family caregivers showed a moderate to high level of affiliate stigma. Those who had regular breaks during patient care, higher time-dependent burden, developmental burden, and physical burden and lower social burden exhibited higher levels of affiliate stigma.
Association between Life’s Essential 8 and estimated pulse wave velocity among adults in the US: a cross-sectional study of NHANES 2011–2018
Authors: Fan Yang , Yang Sisi , Ruan Lei , Zhang Cuntai , Cao Ming
Published: May 2024

Background

Arterial stiffness, typically evaluated via estimated pulse wave velocity (ePWV), is believed to have a significant association with cardiovascular diseases. The objective of this study was to investigate the correlation between Life’s Essential 8 (LE8), a newly revised metric of cardiovascular health, and ePWV among adult population in the United States.

Methods

This research employed a cross-sectional methodology, drawing upon data from the National Health and Nutrition Examination Survey (NHANES) spanning from 2011 to 2018. To explore the relationship between LE8 and ePWV among adults in the US, both univariate and multivariate linear regression analyses were carried out. Additionally, the restricted cubic splines method was utilized to examine any non-linear correlation.

Results

The study comprised 6,742 participants with an average age of 48.30 ± 0.35 years. Among these, 3,236 were males, representing a weighted percentage of 48%. The population’s weighted average LE8 score was 68.68 ± 0.37, while the average ePWV was 8.18 ± 0.04. An entirely adjusted model revealed a negative correlation between ePWV and LE8 scores [in the moderate LE8 group, coefficient − 0.17, 95% CI -0.28 to −0.06, p = 0.004; in the high LE8 group, coefficient − 0.44, 95% CI -0.56 to −0.32, p < 0.0001]. This negative correlation was consistent with the findings in demographic subgroup analysis, with the effect size being more pronounced among adults under the age of 60, and individuals without hypertension, cardiovascular disease, or diabetes.

Conclusion

Our study reveals a negative correlation between LE8 and ePWV in the adult population of the US, suggesting that LE8 could potentially serve as an indicative marker for evaluating the risk of vascular stiffness. This inverse relationship is markedly stronger in adults below 60 years and those without diagnosed vascular diseases. This implies that lifestyle upgrades and risk factor management could be especially advantageous in curbing arterial stiffness within these groups. These conclusions underscore the importance of primary prevention in mitigating the risk of vascular aging in a relatively healthy group, emphasizing the significance of early intervention and risk factor management in cardiovascular disease.
Quantification of sources and potential risks of cadmium, chromium, lead, mercury and arsenic in agricultural soils in a rapidly urbanizing region of southwest China: the case of Chengdu
Authors: Huang Chengyi , Gou Zhangyong , Ma Xinpeng , Liao Guitang , Deng Ouping , Yang Yuangxiang
Published: May 2024

Rapid urbanization a major factor affecting heavy metal contamination on suburban agricultural soils. In order to assess the dynamic contamination of heavy metals in soil from agricultural land bordering a rapidly urbanizing area and the transfer of human health risks from contaminants in this process, 186 and 293 soil samples from agricultural land in suburban Chengdu were collected in September 2008 and September 2017, respectively. Several indicators, such as the integrated pollution index (PI) and the potential ecological risk index (RI), were employed for analyzing the heavy metal contamination levels, and the APCS-MLR receptor model were applied for analyzing the heavy metal sources. As a result, mean concentrations for five elements did not exceed the national soil pollution risk screening values in the two periods mentioned above. Nemerow’s composite contamination index revealed an increase in soil contamination of arable land after 10 years of urbanization, with 3.75 and 1.02% of light and moderate sample plots, respectively, by 2017. The assessment for potential ecological risk indicated an increased level of eco-risk to high for most of the sample plots. Based on the APCS-MLR model, the origin and contribution to the five elements varied considerably between the two periods mentioned above. Among them, soil Pb changed from “industrial source” to “transportation source,” soil Cr changed from “natural source” to “transportation source,” and As and Hg changed from “industrial source” to “transportation source.” As and Hg were associated with agricultural activities in both periods, and Cd was derived from industrial activities in both periods. The study suggests that inhalation has become a major contributor to non-cancer health risks in urbanization, unlike intake routes in previous periods, and that the increase in cancer risk is mainly due to children’s consumption of agricultural products with As residues. The change in the main source of As to “transportation” also indicates a decrease in air quality during urbanization and the development of the transportation industry. This study provides a reference for the governments of rapidly urbanizing cities to formulate relevant highway and agricultural policies to safeguard the health of the people based on the current situation.