bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of Cost Analysis Guidance for Indonesian Hospitals
Authors: Dianingati Ragil Setia , Riewpaiboon Arthorn
Published: February 2020

Health technology assessment is important in the process of national health insurance system development. On the other hand, health technology assessment study needs a cost analysis as a basic, which is a troublesome if there is not any guidance. To help performing the cost analysis study, this study describes the development of a costing manual book and template as a guide for costing analysis in Indonesian hospitals. This management tool developed in stages, from tool drafting, testing in the real life environment, to approval from stakeholders. Costing templates were developed using Microsoft Excel formulas, such as IF, SUMIF and TRANSPOSE. The costing manual book and template were designed for the Indonesian hospital context. The costing template successfully assessed the unit costs of healthcare services in the study hospital. It can calculate the unit costs of healthcare services for 3 main objectives: hospital internal management, reimbursement rate setting and economic evaluation. The costing analysis tool was reviewed and approved by the study hospital staff and stakeholders. Even the model test was only tested in one district hospital, but it was designed to be flexible enough to adapt to different hospital organization structures. The cost analysis guidance is relevant and applicable to district hospitals in Indonesia. It is well accepted by stakeholders and helpful in calculating the hospital unit costs in a practical way. Hopefully, there will be further hospital cost analyses in the future. These cost analyses can then be used as inputs for universal health coverage development.
Evaluasi Luaran Klinis Terapi Antibiotik pada Pasien Community Acquired Pneumonia Anak Rawat Inap
Authors: Tambun Sabrina Handayani , Puspitasari Ika , Laksanawati Ida Safitri
Published: February 2020

Community Acquired Pneumonia (CAP) is an infectious disease which is one of the main causes of child mortality in developing countries. The pattern of giving antibiotics at the hospital is usually still empirical. Inappropriate use of antibiotics may cause failure of therapy or bacterial resistance. This study aims to determine the empirical antibiotic rationality and the relationship of rationality to the clinical outcome of CAP-pediatric inpatients at RSUP. Dr. Sardjito Yogyakarta. The study conducted using a descriptive analytic method with a retrospective cohort design. The subjects were CAP-pediatric inpatients at RSUP. Dr. Sardjito Yogyakarta period 1 January-31 December 2018. The rationality of empirical antibiotics is evaluated using the Gyssens algorithm. The clinical outcome was either good or bad outcome according to the clinician stating in the medical record. Patient characteristics, empirical antibiotic therapy and rationality patterns were analyzed descriptively. The relationship between empirical antibiotic rationality and clinical outcome were evaluated using Chi square test. There were 73 patients who met the inclusion and exclusion criteria (132 empirical antibiotic regimens). Rational antibiotic therapy accounted 76.5% (category 0). Types of irrationality of antibiotic found were IIIB (5.3%) and IIA categories (18.2%). Chi-square analysis showed that empirical antibiotic rationality related to good clinical outcome of CAP children (p = 0.011; OR = 2.957; 95% CI = 1,263 - 6,923).
Luaran Penggunaan Analgesik Opiat pada Pasien Kanker
Authors: Puspita Salma Fajar , Ikawati, Apt. Zullies , Muliawati Retno
Published: February 2020

Cancer pain might reduce the quality of life of cancer patients. Opioids are the drug of choice in cancer pain management. Fentanyl and other opioids are often prescribed. This study was aimed to compare the pain intensity reduction and quality of life of patients with cancer pain using transdermal fentanyl and other opioids. This prospective cohort study Oinvolved cancer outpatients with pain at the Tulip International Cancer Center of RSUP Dr. Sardjito, Yogyakarta fulfilling inclusion and exclusion criteria. Follow-up was carried out 2 weeks after recruitment. Pain intensity and quality of life were obtained through interview process using Numerical Rating Scale (NRS) and EORTC QLQ-C30 questionnaire. Patient demographic and disease status were obtained from medical records. Clinical outcomes (reduction in pain intensity and achievement of pain targets) and quality of life in the transdermal fentanyl and oral opioid groups were presented descriptively because of the low research power. Total respondents involved were 111 patients, 13 (11.71%) patients used transdermal fentanyl and 98 (88.29%) patients used oral opiates. The effect of opioid on reduction of pain intensity, achievement of pain targets and quality of life cannot be justified even though descriptively transdermal fentanyl shows better outcomes than oral opioid. The reduction of pain intensity was influenced by age (p = 0,000) and global health status was influenced by the stage of the cancer (p = 0.045).
Reducing preoperative blood orders and costs for radical prostatectomy
Authors: Gupta Natasha , Visagie Mereze , Kajstura Tymoteusz J , Han Misop , Trock Bruce , Gehrie Eric A , Frank Steven M , Bivalacqua Trinity J
Published: February 2020

Aim:
A maximum surgical blood order schedule (MSBOS) was implemented at our institution to optimize preoperative blood ordering and reduce unnecessary blood preparation for patients undergoing radical prostatectomy (RP), a common urologic procedure.
Materials & methods:
We conducted a retrospective review of patients who underwent RP from 2010 to 2016 and categorized patients by date of RP (pre- or post-MSBOS) and compared preoperative blood-ordering practices.
Results:
After MSBOS implementation, preoperative blood orders changed from predominantly type and cross-match 2 units (53%) to no sample (56%) for robot-assisted laparoscopic RP, and from mostly type and cross-match 2 units (62%) to type and screen (75%) for open RP with resultant cost savings.
Conclusion:
MSBOS implementation and compliance decreases unnecessary preoperative blood orders.
Strike And Power(Lessness) Of The Union
Authors: Stojiljković Zoran
Published: February 2020

The aim of this paper is to identify, on the basis of an analysis of the causes, the course and effects of strikes in Serbia over the last three decades, the mechanisms by which society and trade unions have moved from self-management mythology to the defense of whatever wages and “decent, dignified work” as the maximum goal. The drama of the decay of labor and trade unions, as well as the crisis of society, is presented in three chronologically related acts. The first one describes the process of decay concealed behind the call for patriotism, a kind of socialist-patriotic deception. The second one is the democratic introduction of capitalism through “predatory privatization”. The current, third act, illustrates how neoliberal populism seeks to pacify any resistance of employees and autonomous unions by creating their surrogates through political clientelism and party employment.
Electoral Management in the Western Balkans – Overview of Institutional Setting
Authors: Milenković Marko
Published: February 2020

Countries of the Western Balkans (WB) – former federal units of Socialist Federal Republic of Yugoslavia and Albania have undergone a lengthy and complex process of democratisation from late 1980s. Free and fair elections are among the cornerstones of democratic consolidation. Even though the institutional setting for electoral management differs greatly across the globe, during the Europeanisation process it was widely recommended to transitional societies to set up independent electoral management bodies in other to guarantee fair electoral conditions, with standards mostly promoted by the Venice Commission of the Council of Europe (VC) and International Institute for Democracy and Electoral Assistance (IDEA). Based on this influence, all the countries of the WB have established electoral commissions that are to great extent formally independent from the executive, with the intention of being less prone to electoral meddling. This is enhanced by regular election monitoring in the region by the Organisation for Security and Cooperation in Europe (OSCE) and the process being followed and evaluated by both the European Union institutions and member states as part of fulfilment of the Copenhagen criteria to join the EU. This paper gives an overview of the institutional setting of electoral management in the WB that was created following the model of independent bodies and outlines main features of their design.
Theoretical frameworks for constructing a model for analysis of Islamic discourse on YouTube: one view from Serbia
Authors: Pavlićević Predrag
Published: February 2020

The starting point of this paper an assumption that videos on the YouTube Internet portal relating to Islam produce intolerant and radical discourse that may be a factor of radicalization through their contents, the ways of the shaping of the content, and by their presentation modes. Thus, the aim of the study is to present theoretical frameworks and possible research tools needed to construct a model for the analysis of the Islamic discourse on YouTube. This paper draws on various theoretical approaches, indicate a large number of potential analytical concepts, sub-models, instruments and criteria. It argues in favour of theoretical pluralism, as well as a pluralistic approach and models, openness to accepting diverse methodological instruments, and stresses the need of multidisciplinary in the analysis. Consideration of the relationship between the concepts of politics, discourse and Islamic discourse led to a conclusion about the need of a particular emphasis on the use of critical discourse analysis (CDA) and political discourse analysis (PDA) settings. The results of the research indicate that Islamic discourse on YouTube in a large number of videos, with more or less open manipulative content (visible to the average viewer), aims at consolidating an unquestionable framework of understanding and knowledge of reality – as well as comprehending of the history. Designing a framework for understanding reality and through associated eschatology, the rules of everyday action, principles and limits of tolerance, and identity – especially through discursive strategies and argumentation and beliefs that establish enemies – Islamic discourse on YouTube interprets reality, constructs and impose the only possible reality, and the necessity of achieving the ideal universal Islamic perfection.
ENERGY HARVESTING TECHNIQUES IN WIRELESS SENSOR NETWORKS
Authors: Nikolić Tatjana , Stojčev Mile , Nikolić Goran , Jovanović Goran
Published: February 2020

Batteries are the main source of energy for low-power electronics such as micro-electro mechanical systems (MEMS), wireless sensor networks, embedded devices for remote sensing and control, etc. With the limited capacity of finite power sources and the need for supplying energy for the lifetime of a system/device there is a requirement for self-powered devices. Using conventional batteries is not always good design solution because batteries require human intervention to replace them (very often in hard-accessible and harsh-environmental conditions). Therefore, acquiring the electrical power, by using an alternative source of energy that is needed to operate these devices is a major concern. The process of extracting energy from the surrounding environment and converting it into consumable electrical energy is known as energy harvesting or power scavenging. The energy harvesting sources can be used to increase the lifetime and capability of the devices by either replacing or augmenting the battery usage. There are various forms of energy that can be scavenged, like solar, mechanical, thermal, and electromagnetic. Nowadays, there is a big interest in the field of research related to energy harvesting. This paper represents a survey for identifying the sources of energy harvesting and describes the basic operation of principles of the most common energy harvester. As first, we present, in short, the conversion principles of single energy source harvesting systems and point to their benefits and limitations in their usage. After that, hybrid structures of energy harvesters which simultaneously combine scavenged power from different ambient sources (solar, thermoelectric, electromagnetic), with aim to support higher load at the output, are considered.
DIGITAL MODEL PREDICTIVE CONTROL OF THE THREE TANK SYSTEM BASED ON LAGUERRE FUNCTIONS
Authors: Spasić Miodrag , Antić Dragan , Danković Nikola , Perić Staniša , Nikolić Saša S.
Published: February 2020

The application of the model predictive control (MPC) based on discrete-time Laguerre functions is presented in this paper. A nonlinear three-tank hydraulic system is used as an object to which the proposed algorithm is applied. The paper also presents the method of For the verification of the proposed control method, digital simulations are performed using Matlab.linearization of the nonlinear system, as well as the procedure for the controller design.
EXPLORING PICTORIAL RUNES IN LUCA ENOCH’S COMIC BOOK SERIES GEA
Authors: Tasić Miloš , Stamenković Dušan
Published: February 2020

Drawing on the work of Forceville (2005, 2006, 2011), who employed linguistic tools in analysing comics, the paper deals with pictorial runes as a specific type of visual information found in comic books. As Kennedy (1982) proposes, pictorial runes are graphic devices used in pictures to modify the literal depictions of objects, intended to convey certain aspects of those objects that are otherwise difficult to depict literally. In comics, they are usually employed to imply various emotions, such as anger, fear, pain, or surprise, and indicate speed or the direction of a moving object, among other things. Using the research model presented by Forceville (2011), the paper aims at identifying and categorising pictorial runes in a popular Italian comic book series Gea, in an attempt to corroborate the above method and add to the list of already inventoried runes. Furthermore, the new runes found in this comic book series show evidence of being indexical, rather than symbolic, signs. The paper also briefly outlines the distribution of runes across the entire series.
KINEMATIC PARAMETERS OF JUMP SHOT IN ELITE MALE BASKETBALL PLAYERS
Authors: Stojanović Emilija , Radenković Marko , Bubanj Saša , Stanković Ratko
Published: February 2020

The primary aim of this study was to determine kinematic parameters of jump shot in elite male basketball players, by analyzing the release time for shooting, the angle of entry, and ball spin and. The secondary aim of this study was to examine possible differences in these kinematic parameters among the players associated with their playing position. Eighteen male basketball players (7 guards, 8 forwards, 3 centers) from six Serbian senior teams were tested. 94Fifty basketball sensor was used to obtain the following kinematic parameters of jump shot). The highest average measured values of shot release time were found in centres (1.23±0.23 s) and the lowest in guards (1.07±0.28 s), although these differences were not statistically significant. Further, centres had a lower angle of entry (36.6±2.08°) than guards (40.54±4.76°) and forwards (42.05±3.77°). The highest value of backspin was obtained by forwards (130±11.91 rotations / min). There were no significant differences between guards, forwards and centers in any kinematic variables (p>.01). The relationship between the body height and angle of entry was not significant (p>0.05). In conclusion, compared to centers, guards and forwards showed similar results for the examined variables. This evidence seems to support the theory that compared to guards and forwards centres have the weaker shooting techniques. Coaches should encourage all players, especially centers, to shoot from all positions.
IS PHYSICAL EXERCISE EFFECTIVE FOR IMPROVING VO2max IN PERSONS WITH SCI? A SYSTEMATIC REVIEW
Authors: Stamenković Miloš
Published: February 2020

Maximum Oxygen Consumption (VO2max) is considered to be one of the most relevant indicators of the level of functional ability of the cardiorespiratory system in individuals and athletes. It is an indicator of the functional state and knowledge of the value of VO2max is of great importance in order to improve the functional form for athletes and recreational people, as well as in proper planning, programming and dosing activities. The aim of this study was to review the literature in order to determine whether physical exercise can improve VO2max in people with spinal cord injuries. The following electronic databases were used to collect the papers: KoBSON, Google Scholar, MEDLINE, PEDro, DOAJ and Open J Gate. The key words that were used to find the papers are: physical exercise, VO2max, spinal cord injury, adaptation, training, effects, patients, intensity, aerobic, anaerobic, heart rate. Based on inclusive and exclusive criteria, eight papers were selected that met the set criteria. Analyzing the papers, only four papers examined the differences in terms of the intensity of the exercise with the goal of finding out which intensity is suitable for improving the VO2max value. They have found that the VO2max value can be enhanced by physical exercise of increased intensity (HIIT) relative to physical exercise of moderate intensity (LI). Considering the high level of heterogeneity of scientific papers, the sample of respondents, measuring instruments, experimental research, conclusions should be taken with caution.
TOWARD DEFINING POLICY FRAMEWORK FOR LARGE-SCALE RETAIL IMPACT ADDRESSING IN SERBIA
Authors: Maksić Milica
Published: February 2020

The main objective of this paper was to research how policy framework in Serbia could be improved to address impacts of large-scale retail development. The first step of the research included identifying economical, social and environmental impacts of large-scale retail construction through the review of literature. The second step of the research included the analysis of different type of procedures for retail impact addressing, applied in developed European countries. Finally, policy framework in Serbia was analyzed and recommendations for its improvement are given in accordance with the experiences of European countries.
Contribuições da metodologia das produções narrativas na licenciatura em educação do campo
Authors: Santos Marcelo Loures dos , Silva Diego Gonzaga Duarte da
Published: February 2020

As Licenciaturas em Educação do Campo buscam formar educadores para atuarem nas escolas do campo. São orientadas por processos formativos em alternância, articulando formação na universidade e na comunidade dos educandos. Criar estratégias para a produção de conhecimento na articulação entre estes espaços é um de seus desafios. O objetivo desse artigo é avaliar, a partir do estudo de caso de uma educanda da Licenciatura em Educação do Campo da Universidade Federal de Viçosa, se essa metodologia pode favorecer a articulação entre experiências pessoais e saberes acadêmicos. Foram realizadas três entrevistas narrativas sobre os territórios educativos de sua comunidade, abordando trajetória pessoal, história e contexto local. As narrativas indicaram uma aproximação à lógica da formação por Área de Conhecimento; a articulação entre elementos vivenciais e sua contextualização histórica; e o papel dos sujeitos nas transformações sociais.
The use of Raman and XPS spectroscopy to study the cathode material of LiFePO4/C
Authors: Galaguz Vadym , Korduban Oleksandr , Panov Eduard , Malovanyi Sergiy
Published: February 2020

Using Raman spectroscopy and X-ray photoelection spectroscopy, synthesized lithium iron(II) phosphate (LiFePO4) and carbon coated nanocomposites LiFePO4/?, synthesized by annealing LiFePO4 with glucose for 1 and 12 h at 700?C, have been investigated. According to XPS data, the synthesis conditions of LiFePO4/? nanocomposite (700?C, 1 h) facilitate the reduction of iron, Fe3+ ?Fe2+, on the sample surface. Also according to C1s spectra, sp2C-sp2C is the main bond type in the samples under investigation. Contributions relating to C?O, C=O, C?O?C, O?C=O functional groups are also present. According to X-ray diffraction analysis, a 12-h synthesis of LiFePO4/C nanocomposite leads to the formation of impurities. According to Raman spectra, the annealing time does not affect the quality of carbon coating: the peak intensity ratio of bands D and G has a value of 1.06 for the material annealed for 1 h and 1.04 for LiFePO4/? nanocomposite after annealing for 12 h.
Bioenergy and bioactive components in leaves of Toona sinensis
Authors: Wang Yan , Cui Yilin , Zhang Dangquan
Published: February 2020

Toona sinensis is an important tree for urban greening construction. Toona sinensis sprouts are widely used because of their high medicinal and edible value. However, the functions and effective components of mature Toona sinensis leaves have not been fully exploited and utilized. In order to explore the value of Toona sinensis leaves in bioactive and bioenergy utilization, Toona sinensis leaves were extracted with benzene and ethanol, and then the components in extracts were analyzed by FT-IR and GC-MS. The results showed that benzene and ethanol extracts from Toona sinensis leaves mainly contained phenols, hydrocarbons, esters, alcohols, acids and other bioactive components. These bioactive components can be used in the fields of bioenergy, biomedicine, chemical row materials, food additives and spices. Among them, the content of bioactive components from benzene extract was higher than that from ethanol extract. These findings indicate that Toona sinensis leaves contain a large number of bioactive components which can be used in bioenergy and other fields, and have broad prospects for development.
Molecular characteristics of Salix cheilophila chemical components
Authors: Yang Jun , Chen Juntao , Yang Yafeng , Liu Zhenling , Wang Ting , Peng Wanxi
Published: February 2020

Salix cheilophila plays a role in sand control. However, due to the lack of systematic and in-depth analysis on the chemical composition of Salix chei lophila, it is difficult to develop higher-value products, resulting in low efficiency or even outright abandonment. In this paper, the components of Salix cheilophila and its change rule before/after extraction were introduced, and the thermal loss rules and pyrolysis properties of Salix cheilophila were also explained. The analytic result of FT-IR further confirmed that: the Salix cheilophila contains components including esters, aldehydes, alcohols and ethers, etc., and the organic solvent extraction does not made compound groups of Salix cheilophila significantly changed. There are four obvious stages in thermal loss treatment of Salix cheilophila. During thermal loss treatment, three critical turning points of temperature (44?C, 78?C, and 219?C) were observed, accompanied by significantly chemical changes such as macromolecule pyrolyzed into small volatile molecules. The pyrolysis products of Salix cheilophila extractive including esters, acid, alcohols, aldehyde, ethers, alkene, ammonium, anhydride, phenols, ketone, furans and heterocyclic compounds. There were quite differences among properties and functions of the components. Thus, the application prospects were also significantly different.
Trajectory control and parameter optimization of plasma robot gun
Authors: Chen Xiaohua , Wang Zhanshan , Liu Kailei
Published: February 2020

A plasma robot model with redundant freedom is proposed for the shortage of flexibility in the complex working environment of plasma robot. The existence of redundant degrees of freedom leads to the complex motion characteristics of the plasma robot joints. The trajectory of the end of the spray gun is difficult to describe. Therefore, a trajectory optimization algorithm based on fitness function is proposed. In the plasma robot joint space, a parabolic linear fitting is adopted. The error between the actual trajectory and the desired trajectory is taken as fitness function. Genetic algorithm is applied to find the optimal solution for the parameters in trajectory planning. The orthogonal experimental model of the parameters of the plasma spray gun is set up. The optimum working parameters of the spray gun are obtained through the analysis and study of the power, atmospheric pressure and the distance of the gun. Finally, the rationality of the proposed method is proved by simulation and test.
YouTube as a source of information about orthodontic clear aligners
Authors: Ustdal Gokay , Guney Ayca Ustdal
Published: February 2020

Objectives

To evaluate the content, reliability, and quality of videos about orthodontic clear aligners on YouTube.

Materials and Methods

Researchers used the Google Trends website to determine that the most frequently used search term for orthodontic clear aligners on the Internet was: “Invisalign.” A search was then conducted on YouTube using the key word “Invisalign.” From the first 140 results, 100 videos were selected for analysis. A 13-point content score was used to classify poor-content and rich-content videos, and the global quality scale (GQS) was used to examine quality of the videos. To evaluate reliability of the information, a five-question scale was used. The Mann-Whitney U-test, χ2 test, and Pearson correlation coefficients were used for statistical evaluations.

Results

Of the YouTube videos, 33 were classified as rich content and 67 as poor content. Most videos (73%) were uploaded by laypeople, and most uploaders (71%) were women. The most commonly discussed content was instructions (65%), followed by procedure (57%) and pain (52%). Regarding the GQS, most of the videos were evaluated as moderate quality (51%). Compared with the poor-content video group, the rich-content video group had a significantly higher GQS score (P = .004). There was no significant difference between the poor-content and rich-content groups regarding information reliability (P > .05).

Conclusions

Video content on YouTube relating to aligner orthodontics was generally insufficient. The quality of videos was moderate, but the reliability of information was generally poor. Specialists should refer patients to reliable sources of information.
Comparison of Methods for Determining Activity from Physical Movements
Authors: ÇALIŞAN Mücahit , TALU Muhammed Fatih
Published: February 2020

In this study, the
methods which can detect the basic physical movements of a person (downward,
upward, sitting, stop, walking, running) from inertial sensor data are evaluated.
The performances of classical and current approaches to map IMU data to
activity classes were compared. A three-stage study was carried out for this
aim: 1) data acquisition; 2) creating training/test sets; 3) construction and
classification of network architectures. At the stage of data acquisition, to
obtain 6 different physical movements from 10 different people, the
accelerometer sensor is placed on the persons. Repetitive movements of persons
were recorded. At the second stage, the recorded long-term accelerometer data
is divided into packages in the form of short-term windows. The training set of
classical approaches was constructed by features extracting from each packet
data containing one-dimensional acceleration information. The transformation of
one-dimensional signals to a two-dimensional image matrix for the training set
of the deep learning-based approaches was performed. In the third stage, ANN,
SVM, k-NN and CNN architectures were constructed, and classification process
was carried out. As a result of the experimental studies, it was found that the
accuracy of IMU-activity mapping was 99% with the ANN method and 95% with the
CNN method.
Cyber Diplomacy: Menuju Masyarakat Internasional yang Damai di Era Digital
Authors: Hamonangan Iskandar , Assegaff Zainab
Published: February 2020

Makalah ini bertujuan untuk membahas mengenai diplomasi siber (cyber diplomacy) dan apa yang bisa dijanjikannya untuk menuju masyarakat internasional yang damai di era digital. Ruang siber telah memiliki tempat khusus dan menjadi topik yang sangat penting dalam hubungan internasional. Topik ini telah menjadi arus utama karena sebagian besar aktor-aktor global telah menuangkan kebijakan-kebijakan luar negerinya dan mengadopsi berbagai langkah untuk mengejar tujuan-tujuan stategisnya di dalam ruang siber. Hal ini dapat dilihat misalnya pada penggunaan media sosial oleh Kementerian Luar Negeri untuk mempromosikan negara, kebijakan, dan nilai-nilainya. Namun, kegiatan di ruang siber tidak selalu damai. Terdapat dua kelompok negara yang bersaing untuk tata kelola keamanan siber global dan adanya persaingan antara Amerika Serikat (AS) dan China dalam memperebutkan keamanan siber. Konflik kepentingan antarnegara inilah yang membuat cyber diplomacy diperlukan untuk menengahinya dan mencegah perang siber yang terbuka. Cyber diplomacy adalah praktik internasional yang muncul atas upaya untuk membangun masyarakat siber internasional, dengan menjembatani antara kepentingan nasional negara dan dinamika masyarakat dunia. Oleh karena itu, tujuan dari cyber diplomacy adalah untuk memenuhi fungsi-fungsi tradisional diplomasi, seperti menjaga perdamaian serta membangun rasa saling percaya di antara para pemangku kepentingan, di ruang siber. Makalah ini menggunakan teori Diplomasi dari mazhab English School untuk menganalisis apa yang bisa dijanjikan cyber diplomacy bagi penggunaan ruang siber yang damai. Ada dua fungsi utama dari cyber diplomacy, yaitu sebagai alat komunikasi internasional untuk membangun norma siber bersama dan sebagai upaya untuk meminimalkan gesekan di ruang siber.
Pengelolaan reputasi pemanfaatan ilmu pengetahuan dan teknologi nuklir melalui media online
Authors: Muharromah I Aeni
Published: February 2020

Reputasi merupakan konsep penting bagi organisasi, dibutuhkan waktu yang lama dan upaya berkesinambungan untuk membangunnya. Penggunaan media online dapat dimanfaatkan dengan baik oleh lembaga dalam rangka mengkounter terkait isu nuklir yang sangat sensitif di masyarakat. Penelitian inibertujuan untuk melihat bagaimana pemanfaatkan media online dalam penyebaran informasi mengenai Iptek Nuklir sebagai suatu upaya menjaga reputasi lembaga. Hasil tabulasi setiap berita yang terdiri atas menelaah berita dan mengklasifikasikan sifat pemberitaan yang bernilai positif, negatif dan netral sebagai bahan evaluasi yang dapat menjadi perhatian media. Dengan metode deskriptif-kualitatif, data pemberitaan media online selama tahun 2017 sebanyak 324 buah yang terdiri atas nilai positif 56%, netral 38% dan negatif sebanyak 7%.Adapun isu yang terbanyak adalah mengenai PLTN, diseminasi sosialisasi, aplikasi iptek nuklir bidang kesehatan, pertanian, kecelakaan nuklir dan bidang pangan. Sedangkan 10 media terbanyak memuat pemberitaan nuklir adalah Detik, Tempo, Antara, Tribun, Kompas, Viva, Jawa Post, Republika, Liputan 6, dan Media Indonesia. Untuk isu pemberitaan PLTN menghasilkan kecenderungan negatif sebesar 45% dan medianya adalah Tribun, sebaliknya dengan pemberitaan Tempo sebanyak 9 kali menghasilkan nilai positif sebesar 78%. Dengan pendekatan media coverage, manajemen pemberitaan dan informasi melalui media online, dan pemilihan isu, dan press release yang memuat pesan yang ingin disampaikan organisasi kepada publiknya sangat berkontribusi pada reputasi BATAN.
Rebranding and its Impact on Banking Activities – Case Study
Authors: Kiss Marta
Published: February 2020

Rebranding is regarded as a necessary form when an organisation faces different problems due to the economic transformations of the society that requires new ways of visibility and decides to assign revitalization techniques to the brand image in order to refresh it. Nowadays, most of the Romanian banking companies went through the rebranding process firstly because they were involved in mergers and acquisitions, and secondly, to expand their target markets and to keep their loyal customers in an ever-changing market environment. This study aims to outline the impact of rebranding on a financial institution in Romania, CEC Bank, the oldest Romanian bank operating on the Romanian market since 1864. Following the 2007 rebranding, the purpose of the bank was to create a competitive commercial bank image. For this bank the rebranding process proved to be successful.
Genetic and reproductive toxicity of lamivudine, tenofovir disoproxil fumarate, efavirenz and their combination in the bone marrow and testicular cells of male mice
Authors: Bakare Adekunle A. , Akinseye Kehinde M. , Aminu Bayonle A. , Ofoegbu Francis C. , Anifowose Saheed O. , Abruda Stork , Fadoju Opeoluwa M. , Ogunsuyi Olusegun I. , Oyeyemi Ifeoluwa T. , Alabi Okunola A. , Adetona Olusola M. , Alimba Chibuisi G.
Published: February 2020

The combination of antiretroviral (ARV) drugs: lamivudine, tenofovir disoproxil fumarate (TDF) and efavirenz is among the preferred first-line regimens for adolescents and adults infected with HIV. However, knowledge on in vivo genetic and reproductive toxicity of each of these drugs and their combination is limited. We evaluated the genotoxicity of lamivudine, TDF, efavirenz and their combination utilizing the mouse micronucleus (MN) and sperm morphology tests. Histopathological analysis of the testes of exposed mice was also carried out. 0.016, 0.032, 0.064 and 0.129 mg/kg bwt of lamivudine, TDF and the combination; and 0.032, 0.064, 0.129 and 0.259 mg/kg bwt of efavirenz corresponding to 0.125, 0.250, 0.500 and 1.000 x the human therapeutic daily dose (HTD) of each of the ARVs and their combinations were administered to mice for 5 consecutive days. Data on MN showed a significant increase (p < 0.05) across the tested doses of TDF, efavirenz and the combination, with the combination inducing lower frequency of MN than TDF and efavirenz. Lamivudine did not evoke significant induction of MN. Significant increase in frequency of abnormal sperm cells were observed in the tested samples, however, the combination induced the highest number of abnormal spermatozoa. The ARVs and their combination induced pathological lesions such as vacuolation and necrosis in mice testes. These findings suggest that the individual ARVs and their combination are potentially capable of activating genetic alterations in the bone marrow and germ cells of male mice thereby raising concern for long term use by HIV patients.
A subordination results for a class of analytic functions defined by q-differential operator
Authors: Frasin Basem Aref , Murugusundaramoorthy Gangadharan
Published: February 2020

In this paper, we derive several subordination results and integral means result for certain class of analytic functions defined by means of q-differential operator. Some interesting corollaries and consequences of our results are also considered.
The Possible Ways of Country Brand Communication and Their Classification Based on the POE Model
Authors: Papp-Váry Árpád , Farkas Máté
Published: February 2020

The number of marketing communications tools and channels is steadily increasing – in addition, this growth has been accelerated since the emergence of the Internet and social media. On the one hand, there is an increasing dilemma of which tools one should choose from the plentiful options, and, on the other hand, the (material, human, and time) resources devoted to this are limited. This is valid for the marketing communications of “classic” products, services, and countries. This review article attempts to present the variety of available options with the help of the POE (paid, owned, earned) model and describe their advantages and disadvantages. The novelty of the study is that it focuses on a review of country communication campaigns and initiatives. It offers various visual examples for the different components of the POE model, clarifying the paid media, owned media, and earned media options for country brand communication. It mostly uses examples from Hungary, but other countries’ good practices are also included. Finally, as a result of the analysis, the article summarizes the possible ways of country brand communication according to the POE model in a summary table, which may also contribute to the work of academics and practitioners in the field.
Digital Media Use of Older Adults in Mureş County, Romania
Authors: Vajda András , Tőkés Gyöngyvér Erika
Published: February 2020

This paper analyses the media practices of older adults from Mureş County (village and small town). The first part of this paper examines the integration of digital media into current society and everyday life along with the characteristics of the knowledge and skill acquisition related to digital media. The second half, grounded on empirical qualitative data, offers insight into the digital media practices of older people in Mureş County, Romania, as well as into their opportunities and the contexts regarding the knowledge and skill acquisition necessary for the use of digital media. The paper is based on an exploratory qualitative research aimed at offering insight into the Romanian situation, identifying the obstacles to the digital media use of the older people living in rural areas, and laying the groundwork for a more extended study.
Technical Performance and Perceived Exertion Variations Between Small-Sided Basketball Games in Under-14 and Under-16 Competitive Levels
Authors: Clemente Filipe Manuel , Sanches Rita , Moleiro Carlos Filipe , Gomes Mónica , Lima Ricardo
Published: February 2020

The aim of this study was twofold: i) to compare the rate of perceived exertion (RPE) and the frequencies of technical actions per minute in different small-sided games (SSGs) between under-14 and under-16 age groups, and ii) to compare the RPE and the frequencies of technical actions per minute between 1 x 1, 2 x 2, 3 x 3, 4 x 4 and 5 x 5 formats within age groups. Twenty young male basketball players from the same club (N = 10, from under-14; N = 10, from under-16) competing at the national level voluntarily participated in this study. Five different SSGs (1 x 1, 2 x 2, 3 x 3, 4 x 4 and 5 x 5) were played twice on courts of the same relative area and were compared in terms of the RPE and technical actions. The number of technical-tactical actions per minute, i.e. conquered balls (CB), received balls (RB), lost balls (LB), attacking balls/passes (AB), shots (S), rebounds (R), and the RPE were collected for each player for each SSG session. The results revealed that most of the differences between age groups were considered trivial/small and/or unclear for all SSG formats, though likely moderate differences between age groups were found in 1 x 1 and 2 x 2 SSGs, revealing that young players had greater frequencies of received, conquered, and lost balls. Within-age-group comparisons also showed moderate-to-large increases in technical actions during smaller formats than during larger ones. The main evidence of this study revealed that age group seemed not to largely influence the RPE or technical actions during different SSGs. However, smaller formats moderately-to-largely increased the number of technical actions. Interestingly, the biggest format (5 x 5) largely increased the RPE in comparison to the remaining formats. As a conclusion, technical actions and the RPE were influenced more by the format of play than by the age group.
Notational Comparison Analysis of Outdoor Badminton Men’s Single and Double Matches
Authors: Pérez-Turpin José Antonio , Elvira-Aranda Carlos , Cabello-Manrique David , Gomis-Gomis María José , Suárez-Llorca Concepción , Andreu-Cabrera Eliseo
Published: February 2020

The objectives of this study were to determine the results of the analysis of single and double outdoor badminton men’s matches and to determine the relationship between technical and tactical aspects in a study organized by the BWF (Badminton Word Federation), on a sand surface. Twenty men’s singles matches were recorded using video cameras and analysed with a Dartfish video analysis software package. Along with this, percentages of use of technical elements were analysed by comparing the different modalities. For the single format Lob, Clear, Drop, Smash, Drive were used, different from the double format that used Lob, Clear, Drop, Smash, Drive. The study confirmed the applicability of computerized notation analysis to determine the characteristics of Outdoor Badminton on sand.
Aplasia Cutis Congenita with Unusual Localization – Case Report
Authors: Chiriac Anca , Naznean Adrian , Podoleanu Cristian , Stolnicu Simona
Published: February 2020

Congenital skin aplasia, known more as aplasia cutis congenita (ACC), is a rare congenital disease, characterized by absence of the skin, observed since birth, more often affecting the scalp and rarely the trunk or limbs. We report here for the first time a non-syndromic localized ACC, characterized by a small solitary area of skin atrophy on the cervical area in a healthy 3-day-old female infant.
Ensuring Reliability of Control Data in Engineering Systems
Authors: Dychko A. , Yeremeyev I. , Kyselov V. , Remez N. , Kniazevych A.
Published: February 2020

The paper presents the approach of determination of rationality coefficients of control system, inputted uncertainty, control of the process, system errors, and uncertainty. Algorithms for identifying the states of system have been developed on the basis of theorems of identification. They actually implement the theoretical multiplication cross-section and establish that increasing the reliability of information is possible only through the use of redundancy (structural, procedural, and informational). The increase in the reliability of control data with the developed methods ensures significant improvement of the functioning of information systems and facilitates the adoption of more substantiated decision making.
Diffuse Cutaneous Mastocytosis (Pigmented Maculopapular Cutaneous Mastocytosis) in a Cat
Authors: Szczepanik Marcin , Wilkołek Piotr , Śmiech Anna , Taszkun Iwona
Published: February 2020

Diffuse cutaneous mastocytosis was diagnosed in a 6-year-old, indoor, neutered female domestic European shorthair cat. Marked pruritus located mainly on the head and neck was noticed in the cat and in this area the animal had developed alopecia, crusts, and plaques. Histologically, monomorphic mast cells were found in the superficial dermis and around the hair follicles. Mast cells were well differentiated, with central nuclei and granular cytoplasm, with metachromatic granules which stained positively with Toluidine blue stain. The animal was successfully treated with oclacitinib at a dose of 1 mg/kg, twice a day per os.
Variability of ex-vivo stimulated T-cells secretory profile in healthy subjects
Authors: Manescu Ion Bogdan , Manu Doina Ramona , Serban Georgiana Mihaela , Dobreanu Minodora
Published: February 2020

Peripheral blood lymphocytes (PBL) are able to synthesize various cytokines that play key roles in the immune response and intercellular signaling. Since alterations in cytokine production and/or activity occur in many pathological processes, the study of cytokine synthetic capacity of PBL is a valuable tool for assessing the immune profile. In this paper, we aimed to investigate the variability of interleukin-2 (IL-2), tumor necrosis factor-alpha (TNF-α) and interferon gamma (IFN-γ) synthetic capacity of CD4+/CD8+ T-cells stimulated ex-vivo in healthy subjects, by means of a commercial intracellular cytokine staining (ICS) protocol. Peripheral blood mononuclear cells were isolated from 16 healthy subjects by Ficoll gradient centrifugation and activated ex-vivo with PMA/Ionomycin/Brefeldin-A for 4 hours. Activated PBL were surface-stained for CD3/CD4/CD8, fixed and permeabilized. ICS was performed using anti-human IL-2/TNF-α/IFN-γ and samples were analyzed on a BD-FACSAria-III flow cytometer. We recorded high post-isolation and post-activation mean viabilities: 82.1% and 82.4% respectively, p=0.84. Both CD4+/CD8+ subpopulations were found to partially produce each of the three cytokines, but in different proportions. On average, a significantly greater percentage of CD4+ cells was shown to produce IL-2 and TNF-α, compared with CD8+ cells (61.5%+/-5.8 vs. 25%+/-5.6 and 26.9%+/-11 vs. 7.5%+/-3.3 respectively, p---lt---0.0001 for both). Contrarily, IFN-γ was produced by a higher proportion of CD8+ cells (8.4%+/-3.9 vs. 6.8%+/-3.2, p=0.01). These results show that the employed ICS protocol elicits a satisfactory and consistent cytokine response from PBL of healthy subjects. The collected data may be used to outline a preliminary reference range for future studies on both healthy/pathological subjects.
The direct deleterious effect of Th17 cells in the nervous system compartment in multiple sclerosis and experimental autoimmune encephalomyelitis: one possible link between neuroinflammation and neurodegeneration
Authors: Balasa Rodica , Maier Smaranda , Barcutean Laura , Stoian Adina , Motataianu Anca
Published: February 2020

The processes of demyelination and neurodegeneration in the central nervous system (CNS) of multiple sclerosis (MS) patients and experimental autoimmune encephalomyelitis (EAE) are secondary to numerous pathophysiological mechanisms. One of the main cellular players is the Th17 lymphocyte. One of the major functions described for Th17 cells is the upregulation of pro-inflammatory cytokines, such as IL-17 at the level of peripheral and CNS inflammation. This review will focus on the newly described and unexpected, direct role played by the Th17 cells in the CNS of MS patients and EAE models. Th17 and their main cytokine, IL-17, are actively involved in the onset and maintenance of the immune cascade in the CNS compartment as Th17 were found to achieve brain-homing potential. Direct interaction of myelin oligodendrocyte glycoprotein - specific Th17 with the neuronal cells firstly induces demyelination and secondly, extensive axonal damage. The Th17 cells promote an inflammatory B cell response beyond the BBB through the presence of infiltrating Th follicles. Due to their role in preventing remyelination and direct neurotoxic effect, Th17 cells might stand for an important connection between neuroinflammation and neurodegeneration in a devastating disease like MS. The Th17 cell populations have different mechanisms of provoking an autoimmune attack not only in the periphery but also in the CNS of MS patients.
Gastric cancer is associated with a high rate of microsatellite instability versus chronic gastritis: A retrospective study
Authors: Xing Li , Guo Hua , Zheng Dongjie , Liu Jin , Zhou Baojun , Li Yanping , Wang Ning , Zhao Pu , Liang Yan , Wu Wenxin , Li Guixin
Published: February 2020

Objective: Microsatellite instability (MSI) in gastric cancer contributes to genetic complexities of gastric cancer. In the current study, we employed a panel of mononucleotide and dinucleotide markers to detect MSI in 99 gastric cancer patients and 91 chronic gastritis patients and further analyzed the association of MSI with clinicopathologic variables of the study patients.

Methods: We retrospectively analyzed the clinicopathologic data of primary gastric cancer patients and chronic gastritis patients. MSI was analyzed using five microsatellite markers, including D2S12, D5S346, D17S799, BAT26, and D18S34. MSI was defined as either a band shift or the appearance of a novel band in DNA. Multivariate logistic regression analysis was used to predict risk of MSI.

Results: Seventeen (17.2%) gastric cancer patients and 7 (7.7%) chronic gastritis patients were positive for MSI (P=0.012). Multivariate analysis further showed that gastric cancer was associated with a significantly higher likelihood for MSI versus gastritis (OR 3.73; 95% CI 1.19, 11.72; P=0.024) while age, drinking or smoking was not associated with increased MSI.

Conclusion: Gastric cancer is associated with a high rate of MSI. MSI should be further explored in future studies with a larger sample size for its role in gastric cancer development and as a predictive biomarker.