bluuebunny/crossref_metadata_2025 huggingface dataset:
PROCESSO DE INCLUSÃO/EXCLUSÃO DIGITAL DE PROFESSORES EM FORMAÇÃO CONTINUADA EM UM AMBIENTE VIRTUAL
Authors: Godoi e Silva Kátia Alexandra , Lima Paniago Maria Cristina , Martins Régis dos Santos Rosimeire
Published: November 2018

O artigo discute as relações de inclusão/exclusão digital de professores em processo de formação continuada em um ambiente virtual. Desenvolvemos uma pesquisa qualitativa, com quatro professores participantes de um grupo de pesquisa, a partir das seguintes estratégias: entrevistas reflexivas e narrativas. Priorizamos tecer os referenciais teóricos juntamente com a análise dos dados construídos, tendo em vista três agrupamentos: redimensionamento do tempo; convergência e divergência entre professores e mídias; autonomia e mediação contextualizada. Os achados possibilitaram a visualização do imbricamento das três temáticas, as quais impedem, dificultam ou promovem a inclusão/exclusão dos professores em tal formação.
POLÍTICAS PÚBLICAS EDUCACIONAIS: FOCO NA INCLUSÃO DIGITAL
Authors: Coelho Neves Barbara , Couto Cunha Maria
Published: November 2018

O artigo trata das políticas públicas implementadas na educação com enfoque para inclusão digital. Tem como objetivo abordar o conceito de política pública na educação considerando a inclusão digital. Para nortear a discussão, desenhou-se objetivos específicos que visaram destacar as principais linhas de pesquisa que abordam políticas públicas educacionais para a inclusão digital; discutir alguns aspectos contextuais do conceito de política pública na educação; e observar as políticas públicas voltadas para inclusão digital na educação. Trata-se de um artigo de reflexão elaborado com o apoio de dados bibliográficos e documentais, podendo ser considerado revisão de literatura em seu aspecto geral. Entretanto, contou com um breve levantamento em banco de dados (BTD-Capes) para identificar as principais linhas de pesquisa do tema na Educação. Tem como principal resultado a agenda das políticas públicas voltadas para a inclusão digital na Educação brasileira desde a década de 1970. Considera-se finalmente, a necessidade de se observar alguns elementos em torno das políticas públicas possíveis de problematização para continuidade da agenda de inclusão digital.
POR UMA FORMAÇÃO NÃO FASCISTA: EXPERIMENTAÇÕES DOCENTES NA CIBERCULTURA
Authors: Da Silva Ponte de Carvalho Felipe , Pocahy Fernando , Oliveira dos Santos Edméa
Published: November 2018

A cibercultura é a cultura contemporânea conectada pelas redes digitais, cultura que vem sendo marcada também por práticas de viés fascistas: racismo; machismo, LGBTIfobia, violência contra a mulher, xenofobia... Nesse sentido, esta pesquisa-formação na cibercultura tem como objetivo pensar-fazer a formação docente não fascista em tempos de cibercultura, a partir do cuidado de si, vida não fascista, cidadania horizontal, docência online e partilha. A pesquisa foi realizada com cursistas da disciplina de Informática na Educação do curso de Pedagogia Uerj/Cederj/UAB, por meio de duas ambiências híbridas-formativas em atos de currículo, que constituíram a “Aula 2 - Fascismo em rede”, criada pela plataforma Moodle, composta por artigos, vídeos, fórum de discussão e produção de histórias em quadrinhos. Ao experienciarmos o cotidiano desta pesquisa-formação encontramos: narrativas de cursistas que articulavam ideias para uma prática docente não fascista; narrativas da escola como um espaço-tempo plural e de problematização; ações cotidianas para discutir o fascismo que está em nós, em nossas práticas. Estas narrativas nos remetem a reflexões em torno de uma formação voltada para mais participação social em rede, inclusiva, múltipla.
ANÁLISE CURRICULAR DO CONTRATURNO NA ESCOLA DE TEMPO INTEGRAL EM MINAS GERAIS
Authors: Dos Santos Felício Helena Maria
Published: November 2018

Este trabalho tem por objetivo analisar a organização curricular do contraturno da Escola de Tempo Integral (ETI), em Minas Gerais, com o intuito de perceber nele os indicadores que apontam para a dimensão de uma Educação Integral. A partir da concepção de Educação Integral, a pesquisa privilegiou a abordagem qualitativa pela qual foi possível perceber que, apesar dos benefícios oferecidos aos educandos que permanecem na escola em tempo integral, o currículo do contraturno, no projeto ETI é organizado na perspectiva do reforço escolar, distanciando dos objetivos propostos pela Educação Integral.
Resíduos sólidos orgânicos na construção de composteira em uma escola pública em São Luís, Maranhão, Brasil
Authors: Valle Mariana Guelero , Utta Ana Cristina
Published: November 2018

Cotidianamente, produzimos resíduos que, na ausência de coleta seletiva, acabam sendo depositados de maneira inadequada no meio ambiente. O objetivo deste trabalho foi sensibilizar alunos acerca da problemática do lixo enfatizando a importância da reciclagem a partir do processo de compostagem. Foram realizadas campanhas de sensibilização nas salas de aula, em seguida feita uma lista com os alunos voluntários a participar da implementação da composteira na escola. A execução do projeto resultou em uma forma alternativa de redução de resíduo sólido, bem como contribui para a formação de conhecimento para os alunos da escola. Campanhas de sensibilização são uma importante alternativa para alcançar cada vez mais pessoas, uma vez que ações de educação ambiental devem ter um caráter contínuo junto à comunidade.
Sobre o programa de saúde na escola e o protagonismo juvenil
Authors: Moura Eliana Gonçalves , Pereira Gislaine Cristina , Zuffo Sílvia
Published: November 2018

A presente pesquisa foi desenvolvida junto ao grupo de Jovens Multiplicadores (JM) do Programa Saúde na Escola (PSE), do município de Novo Hamburgo/RS, o qual tem a finalidade de promover a saúde juvenil nos seguintes eixos: gravidez na adolescência, DST’s, violências, uso de drogas e álcool. A investigação buscou aproximação do JM, e evidências de protagonismo juvenil pretendida por tal política. Por meio da técnica da observação participante, foram acompanhadas cinco reuniões ocorridas nos meses de maio/junho de 2016. As discussões, bem como os dados descritivos dos encontros, foram registradas em diário de campo. Como resultado, constata-se que o protagonismo juvenil assume outras características, e não a emancipação do indivíduo.
A ética do discurso em Habermas
Authors: Salles Sergio De Souza , Da Silveira Fernandes Geovana Faza
Published: November 2018

O defensor da universalidade no campo moral deve reconhecer os problemas vinculados à historicidade e à singularidade conflituosa das morais pertencentes ao mundo da vida. Pretende-se apresentar os princípios universais fundadores da moral propostos por Jürgen Habermas como parte de um percurso de justificação da ética, comprometida com a moral do respeito indistinto e da responsabilidade consensual e solidária por cada um. Procura-se, assim, avaliar de que modo o filósofo concilia a defesa da autonomia do julgamento moral de cada um com a expectativa do consenso de todas as pessoas enquanto participantes das discussões morais práticas.
Percepción del alumnado de primer ciclo de educación secundaria sobre su salud desde la perspectiva del profesorado
Authors: Caracuel Rafael , Guerreiro António
Published: November 2018

El objetivo de este trabajo es conocer la opinión del profesorado sobre los conocimientos en salud que tiene el alumnado y qué beneficios piensan los adolescentes que la práctica de actividad física produce en su salud. Vamos a analizar los conocimientos, pensamientos y creencias del alumnado de primer ciclo de educación secundaria acerca de su concepción de la salud y de su imagen corporal, contrastadas con la percepción del profesorado de educación física. Para ello hemos realizado un Grupo de Discusión, en el que han participado 8 profesores de Educación Física. La información obtenida la hemos procesado a través del programa Nudits Vivo. Los resultados indician que el profesorado considera de manera mayoritaria que su alumnado tiene un concepto difuso de lo que es la salud, aunque indiquen ciertos indicadores que hacen presumir que intuyen lo que es beneficioso o lo que no lo es. Así también manifiestan que el alumnado tiene conocimientos y hábitos de seguridad en la práctica de actividades físico-deportivas. Además se detecta que resulta difícil que se produzca una modificación de la conducta alimentaria, si al mismo tiempo no se promueven los cambios en los contextos familiares y sociales.
Pós-colheita de frutos de juazeiro em diferentes estádios de maturação
Authors: Silva Jéssica Leite da , Costa Franciscleudo Bezerra da , Nascimento Ana Marinho do , Costa Rafaela Teixeira Rodrigues do Vale , Formiga Anderson Dos Santos
Published: November 2018

O juazeiro (Ziziphus joazeiro Mart.) conhecido popularmente como juá é uma planta típica do Nordeste brasileiro, bastante utilizada na alimentação animal em épocas de seca prolongada, no entanto, seus frutos são pouco estudados e caracterizados. Nesse enfoque, objetivou-se avaliar a qualidade pós-colheita de frutos de juazeiro em diferentes estádios de maturação. Os frutos foram colhidos de plantas localizadas no Centro de Ciências e Tecnologia Agroalimentar, da Universidade Federal de Campina Grande, Campus Pombal-PB. Os frutos foram selecionados quanto à ausência de injúrias e classificados em cinco estádios de maturação, conforme a coloração da casca do fruto. Avaliaram-se características físicas, físico-químicas, composição centesimal e compostos bioativos. Os resultados apontam que os frutos de juazeiro apresentam elevado rendimento de polpa, alta concentração de sólidos solúveis, de ácido ascórbico e de compostos fenólicos, indicando o provável potencial antioxidante dos frutos, em especial no estádio de maturação I e IV.
Modificações paisagísticas e implicações térmicas no distrito administrativo de Belém, Pará
Authors: Takashima-Oliveira Tássia Toyoi Gomes , Bezerra Paulo Eduardo Silva , Pontes Altem Nascimento , Tavares-Martins Ana Cláudia Caldeira
Published: November 2018

As modificações paisagísticas no uso e cobertura da terra podem implicar em alterações na dinâmica de ecossistemas e no clima local. Assim, objetivou-se verificar se o padrão de uso e cobertura da terra contribui para a existência e ou aumento de ilhas de calor no distrito de Mosqueiro, Pará. Foram levantados dados qualitativos por meio de entrevistas não formais com moradores para se conhecer as formas de uso e manejo das propriedades. Os dados quantitativos foram obtidos através de imagens temáticas da ilha correspondentes ao período menos chuvoso da região nos anos de 2010, 2013 e 2015. A classificação do uso e cobertura da terra na ilha de Mosqueiro seguiu o critério não supervisionado. Os dados de temperatura de superfície (TS) foram obtidos por meio dos valores de radiância espectral, da banda termal dos satélites Landsat 5 e 8. Para determinação de ilha de calor, considerou-se a resultante da diferença das temperaturas entre a classe de área urbana e a de floresta. No período de 2010 a 2015, constatou-se redução de área em 9,1% de floresta, pelo crescimento da infraestrutura urbana e pelo desmatamento na região, fato corroborado com a percepção dos moradores locais. Essas modificações resultaram em mudanças na TS, com aumento médio de 5.15°C, mesmo que não se tenha constatado a ocorrência de ilha de calor no espaço urbano. Diante do exposto, verificou-se que as variações da TS estão inteiramente relacionadas às mudanças nas classes de uso e cobertura da terra na ilha e que tende a intensificar sem o planejamento ambiental adequado.
Sustentabilidade ambiental da pegada hídrica na sub-bacia do Alto Piranhas no sertão paraibano
Authors: Cândido Luíza Lilandra Teixeira , Vieira Allan Sarmento , Silva Érika Lira da , Fernandes Francisco Dinarte De Sousa , Sá Neto José Abrantes De , Cândido Raimundo Alves
Published: November 2018

Os avanços na gestão da água exigem conhecimento da disponibilidade e da demanda de recursos hídricos, como subsídio para definir ações prioritárias que possam conservar o uso adequado da água. Esse artigo tem como objetivo principal, determinar a pegada hídrica na sub-bacia do Alto Piranhas, localizada no sertão paraibano, no ano de 2015, analisando através de cenários de operação a sua sustentabilidade. Com base nisto, foram feitos estudos com os métodos da pegada hídrica a fim de verificar a sua eficiência e eficácia na geração de informações sobre a quantidade de água consumida nos principais setores de utilização da água, como também analisar a sustentabilidade da sub-bacia estudada. A pesquisa se classifica como exploratória e descritiva, uma vez que envolve pesquisa bibliográfica, estudo de caso, coleta de dados e ainda estabelece relações entre variáveis para que possa chegar ao resultado final. Os resultados demonstraram, para o ano de 2015, que a sub-bacia é sustentável, apesar de termos um ano considerado muito seco e apresentar práticas ineficientes. Porém, quando analisado no período de julho a dezembro a sub-bacia apresentara altos índices de escassez e poluição, devido à diminuição das vazões naturais. Portanto, os estudos na sub-bacia do Alto Piranhas, irão subsidiar o gestor público numa tomada de decisão precisa e promover consequentemente o fortalecimento do sistema de gerenciamento de recursos hídricos que busca uma governança sustentável.
The role and impact of politics on the Art of Pakistan for undergraduates
Authors: Ali Alia Hadi
Published: November 2018

There was a quantitative research done on role and impact of politics on the Art of Pakistan. Art students have an introduction to political scenario affecting art. The target audience chosen were the undergraduates of Art and Design College Punjab University and National College of Arts in Lahore. This paper works as a parameter. The students are aware that Art can be influenced, moulded and reface with political influence. The selected audience is going to get affected by the policies and commandment of political structure which is present and affecting all professions of Pakistan. After the survey forms were filled by the student of bought institutions,the results of both institutions were compared. Furthermore, this paper helps in adding topics taught in the history of Art in graduate level in a way that what are the circumstances which can be requested by the government to look upon for the promotion of Art.Keywords: First keyword, second keyword, third keyword, forth keyword;
Position paper mixed ceramic and porcelain on mud example applications
Authors: Ozkanli Nilufer Nazende
Published: November 2018

It has been observed that organic or inorganic materials such as grass, straw, fibrous plants, plant roots and mineral additives have been added to the ceramic bodies in order to be stronger throughout history. The use of paper as an additive material. It is known that in the past years, a mixture called â€˜Papier Macheâ€™ in India has been used in papermaking in ceramics. Nowadays, many ceramic artists use paper additives in their artistic applications. Cellulosic fibres are a ceramics body since it prevents creaking of the ceramic during the course of drying of the ceramic due to its binding properties when mixed with clay as well as its lightness after firing. In this study, the use of the paper additive in kaolin, some sample applications and samples from artist works have been presented.Keywords: Porcelain, artistic ceramic, paper additive ceramic.
Use of experimental materials in illustrations: Illustrated notebook designs
Authors: Turkmen Banu Bulduk
Published: November 2018

The illustration is a field kneaded with contemporary interpretation languages and finds a new breath with the forms used in new media environments. Similarly, this doesnâ€™t substitute for the traditional materials so artists continue to describe what is intended on various surfaces and encourage artists to develop alternative languages in their illustrations. When the tendency of illustratorâ€™s interpretation is combined with the idea of bringing paper and material together, the formation of originally designed areas is the result of this orientation. This article focuses on the diversity of the areas in which paintings are expressed. With the illustrations that also come to life on the surfaces of different textures, sketchbooks are transformed into valuable objects of design. The examination of this situation is covered by the method of the article, the formal analysis of the design objects is presented with examples, and the research is completed by examining the place of the experimental materials in the illustrations.Keywords: Illustration, illustration language, illustration techniques, sketchbook, illustrated notebook.
How to achieve a right graphic representation for a logo
Authors: Pasu Nicoleta Elisabeta , Adir Victor , Carutasu Nicoleta Luminita , Adir George
Published: November 2018

The graphic world of logos is interesting and creative. In this paper, we have pleaded about â€˜the graphic techniqueâ€™ to design good logos using a few essential principles to do it. To draw a graphic representation, as a logo, somebody has to know a peculiar language made of symbols, signs, colours, geometric shapes and words. Because the typology of logos is interesting and allows to create icons, logotype and complex graphic representations. Our study has analysed a lot of logos to identify the main principles â€˜to buildâ€™ them. It was a hard work of observation and explanation about logos using many examples. We think we have shown the power of graphics in our study.Keywords: Special graphic language, logo, principles, typology, creative work.
A study concerning the presence of stylised human body in logo design
Authors: Adir Victor , Pascu Nicoleta Elisabeta , Adir George , Carutasu Nicoleta Luminita
Published: November 2018

This paper talks about the stylised human body used in logo design. During our research, we have seen many logos which have had a stylised shape of animals, insects, birds and human being as a graphic representation. That was the reason to determine us â€˜to digâ€™ deeper in this field of stylisation shape. Because this field is huge, we were obliged to connect our study only to the human body, as a stylised graphic representation in logo design. One of the results of the research study in this paper, where we have tried to explain what kind of graphic elements, colours, geometric shapes and graphic techniques are used to design interesting logos. For us, it was a challenge because we have analyzed a human body as a stylised whole or parts to join the entire body. We think we have managed this work.Keywords: Human stylised body, logo, geometric shape, graphic techniques, colours.
Re-reading Nicosiaâ€™s urban transformation architecturally
Authors: Saglam Hakan , Anil Gaye
Published: November 2018

All cities are transformed and changed in the time being. This change is an important database for people who work in the design area to theorize the future. Nicosia, which was on the focus of important changes as a capital city, witnessed important changes in the past and today and especially after the recent policies it started to experience rapid changes. The aim of this research is to identify the change in the Nicosia cityâ€™s most important line Kyrenia Gate and Eleftheria Square and prepare a baseline for future decisions. These changes also effected from social, economic and cultural change through architecture, also we try to classify the data to reflect the predicted transformation and create sources for prospective studies.Keywords: Urban transformation, Kyrenia Gate-Eleftheria Square line.
The body that contemporary art fragments
Authors: Emrali Refa
Published: November 2018

Along with the history of humankind, the adorable female body which ensures the continuity of the human race has been a field where the socio-cultural structure can be read in a contemporary art. The body, which was preliminarily a whole and a material for aesthetic categories, starkly began to get fragmented with wars in the 17th Century Europe and following the war, with egalitarian, liberal formations of 1968 movement. During the course of the change from modernism to post-modernism, the chaotic structure caused by global lifestyles made it inevitable to review the existing genres. The world wars, genocides that many scientists and artists left their countries, escaping from invasions, the regional and mass destruction, threat, violence and the anxiety caused by them; the fear, the politicisation, racism, poverty, migration, marginalisation, deterritorialisation, discrimination that started during especially the 1980s, have been concepts that were considered with a poststructuralist point-of-view.

Keywords: Body, art, female, gender, violence.
Career Education and Integrated Curriculum
Authors: Gonzalez-Herrera Ana Isabel , Márquez-Domínguez Yolanda
Published: November 2018

The article presents an action research process for the improvement of Vocational Guidance and Career Education in a school center in Santa Cruz de Tenerife (Canary Islands). The research perspective, from a collaborative and critical work, responds to the need to improve the teaching-learning practice. Priority is given to the ulterior need to improve learning for all students and increase the impact of their journey through school by means of an educational attention and guidance based on a curriculum project with an integrated and global Career Education and Guidance. Finally, results, process and conclusions are displayed of the two years of critical action research carried out by the different educational agents participating.
Effect of Gender on the Outcome of Patients Receiving Immune Checkpoint Inhibitors for Advanced Cancer: A Systematic Review and Meta-Analysis of Phase III Randomized Clinical Trials
Authors: Grassadonia Antonino , Sperduti Isabella , Vici Patrizia , Iezzi Laura , Brocco Davide , Gamucci Teresa , Pizzuti Laura , Maugeri-Saccà Marcello , Marchetti Paolo , Cognetti Gaetana , De Tursi Michele , Natoli Clara , Barba Maddalena , Tinari Nicola
Published: November 2018

Evidence has recently emerged on the influence of gender on the immune system. In this systematic review and meta-analysis of phase III randomized clinical trials (RCTs), we explored the impact of gender on survival in patients with advanced cancer treated with immune checkpoint inhibitors (ICIs). We performed a comprehensive search of the literature updated to April 2018, including the Cochrane Central Register of Controlled Trials, PubMed, and EMBASE. We extracted data on study characteristics and risk of bias in duplicate. Of 423 unique citations, 21 RCTs were included, inherently to 12,635 patients. Both males and females showed reduced risk of death associated with ICIs use (HR 0.73, p<0.001 and HR 0.77, p<0.001, respectively). Subgroup analyses by specific ICI showed similar OS in both genders for anti-PD-1/PDL-1. Anti-CTLA-4 use was associated with longer OS in men only (HR 0.77, p<0.012), with the exception of melanoma (in women, HR 0.80, p=0.006). PFS was longer in men than in women (HR 0.67, p<0.001 and HR 0.77, p=0.100, respectively). Conclusively, ICIs use was associated with more favorable outcomes in men, particularly for anti-CTLA-4 agents. In melanoma, not gender-related factors may influence the anti-tumor immune response evoked by ICIs.
User Satisfaction in Augmented Reality-Based Training Using Microsoft HoloLens
Authors: Xue Hui , Sharma Puneet , Wild Fridolin
Published: November 2018

With the recent developments in augmented reality (AR) technologies comes an increased interest in the use of smart glasses for hands-on training. Whether this interest is turned into market success or not depends at the least on whether the interaction with smart AR glasses satisfies users, an aspect of AR use that so far has received little attention. With this contribution, we seek to change this. The objective of the article, therefore, is to investigate user satisfaction in AR applied to three cases of practical use. User satisfaction of AR can be broken down into satisfaction with the interaction and satisfaction with the delivery device. A total of 142 participants from three different industrial sectors contributed to this study, namely, aeronautics, medicine, and astronautics. In our analysis, we investigated the influence of different factors, such as age, gender, level of education, level of Internet knowledge, and the roles of the participants in the different sectors. Even though users were not familiar with the smart glasses, results show that general computer knowledge has a positive effect on user satisfaction. Further analysis using two-factor interactions shows that there is no significant interaction between the different factors and user satisfaction. The results of the study affirm that the questionnaires developed for user satisfaction of smart glasses and the AR application performed well, but leave room for improvement.
Development Model of  Synergistic Sustainable Marine Ecotourism (Case Study in Pangandaran Region, West Java Province, Indonesia)
Authors: Nurhayati Atikah , Aisah Isah , Supriatna Asep K
Published: November 2018

Coastal areas in the South Coast of West Java Province have the potential to develop marine ecotourism, one of which is the Pangandaran area which must be transferred into economic value by not damaging natural resources. Marine ecotourism development is not only intended to raise foreign exchange for local governments, but are also expected to play a role in maintaining natural resources sustainably. This research aims to analyze the sustainable synergistic marine ecotourism development model. The method used in this research using quantitative descriptive method. The Quantitative descriptive method is used to describe the general condition of the research area, using primary and secondary data. The technique of taking respondents using accidental sampling as many as 50 respondents consisting of tourists, public figures, fishermen who have side jobs as a provider of marine ecotourism services. The analysis tool used is through a Rapfish model approach to measuring the synergistic model of sustainable development of marine ecotourism. Based on the results of a research on a sustainable synergistic marine ecotourism development model by measuring the ecological dimensions of environmental services in high conditions, the economic dimension of marine ecotourism is in moderate condition. Marine ecotourism technology in low conditions and social dimensions of marine ecotourism in low conditions. Model development of sustainable marine ecotourism synergistic with regard to the dimension of environmental, economic and social institutions should be able to form integrated from infrastructure to support marine ecotourism up to raise the level of income of fishermen who have a second job as a marine ecotourism providers. The infrastructure and regulatory dimensions are recommended to use the technology information to promote marine ecotourism optimally and regulations need to make marine ecotourism zoning rules and infrastructure improvements.
DNA Sequences of Small DNA Tumor Viruses, Merkel Cell Polyomavirus and Human Papillomavirus, in Spontaneous Abortion Specimens
Authors: Tagliapietra Andrea , Rotondo John , Bononi Ilaria , Mazzoni Elisa , Magagnoli Federica , Oton Gonzalez Lucia , Contini Carlo , Vesce Fortunato , Tognon Mauro , Martini Fernanda
Published: November 2018

Background. The role of viruses in spontaneous abortion (SA) in not completely known. Methods. Merkel cell polyomavirus (MCPyV) and Human papillomavirus (HPV), two small DNA tumor viruses, were investigated in SA. MCPyV/HPV DNAs were investigated by PCR and droplet-digital/quantitative PCRs (ddPCR/qPCR) in chorionic villi and peripheral blood mononuclear cells (PBMCs) from SA females (n=100), the cases, and voluntary interruption (VI, n=100) of pregnancy females, the controls. Results. MCPyV DNAs were detected in 4% and 5% of SA and VI chorionic villi, respectively, with a mean DNA load of 1.99 copy/104 cells in SA and 3.02 copy/10,000 cells in VI (p>0.05). HPV DNAs were detected in 2% of VI chorionic villi, with a mean DNA load of 7.12 copy/cell. Two cases in the VI samples were HPV-45 positive. In PBMCs, MCPyV DNA was detected in 9% and 14% of SA and VI samples, with a mean viral DNA load of 2.09 and 4.70 copy/10,000 cells in SA and VI samples, respectively (p>0.05). None of PBMCs samples tested HPV-positive. Conclusions. MCPyV and HPV DNAs were quantified, for the first time, by ddPCR/qPCR in SA and VI chorionic villi and PBMCs. Data of the present study may help to better understand the role of MCPyV/HPV in SA.
Acute Exacerbation of Idiopathic Pulmonary Fibrosis
Authors: Kishaba Tomoo
Published: November 2018

Idiopathic Pulmonary Fibrosis (IPF) is most common idiopathic interstitial pneumonias. IIPF is often seen in elderly smoker man. Diagnosis of IPF is integration of detailed clinical history, specific physical examination, laboratory findings, pulmonary function test, chest high-resolution computed tomography (HRCT) and pathology. IPF have heterogeneous clinical course from asymptomatic stable state to progressive respiratory failure or acute exacerbation (AE). AE of IPF have several important differential diagnosis such as heart failure and volume overload. International working project proposed new criteria of AE of IPF in 2016. They divided into triggered and idiopathic AE. On the basis of this criteria, physician can capture AE of IPF more easily. Recent international IPF guideline emphasized the utility of chest HRCT. In addition, two anti-fibrotic agents have been available. We should pay attention to not only management of AE, but also prevention it. I review diagnostic process, laboratory findings, typical chest imaging, management and prognosis of AE.
An Explaining Theory for Diuretic-Induced-Diabetes Incidences
Authors: Yousef Farah , Mansour Oussama , Herbali Jehad
Published: November 2018

Many patients with hypertension are also suffering from Type II Diabetes Mellitus (TIIDM). Different studies argued the fact if these patients can use Hydrochlorothiazide (HCTZ) group or not to treat hyper-tension as these diuretics are accused with diuretic-induced diabetes especially Chlorthalidone and Bendroflumethiazide. As nothing is definite yet; in this paper, we are jotting down a new theory. In other words, we are seeking to study HCTZ interactions with sulfonylurea receptor Kir 6.2\SUR1 considering the chemical fact that HCTZ are also sulfonamide derivates like sulfonylurea drugs which are hypoglycemic agents used in the treatment of TIIDM. Therefore, we have studied in-silico 12 HCTZ compounds’ interactions with the binding site of sulfonylurea in its receptor Kir6.2\SUR1. Then, we compared the results to the interactions of Glibenclamide (GBM); a sulfonylurea agent, with the named receptor.  As a result, three compounds of this family (Chlorthalidone 1-1, Bendroflumethiazide 4-1, Metholazone 6-1) had bound to Kir6.2\SUR1 receptor in the same binding site of GBM. The rest members were almost close to the GBM binding site. These findings may explain the adverse effect that chlorthalidone and Bendroflumethiazide are accused with. We suggest that they are agonists for Kir6.1\SUR1 receptor, which results in decreasing insulin secretion from pancreas which consequences with hyper-glycemica. On the other hand, our results confirm that developing new anti hyperglycemia agents from HCTZ as a lead compound is also possible and promising.
A Sparse Autoencoder and Softmax Regression based Diagnosis Method for the Attachment on the Blade of Marine Current Turbine
Authors: Xin Bin , Wang Tianzhen , Zheng Yilai , Wang Yide
Published: November 2018

The development and application of marine current energy are attracting more and more attention in the world. Due to the hardness of its working environment, it’s important to study the fault diagnosis of marine current generation system. In this paper, underwater image is chosen as the fault diagnosing signal after different sensors are compared. The faults are set by simulating varying degrees of biological attachment in the actual working environment of marine current turbine (MCT). This paper proposes a diagnosis method based on the improved sparse autoencoder (SA) and softmax regression (SR). The improved SA is used to extract the features and SR is used to classify them. Images are used to monitor whether the blade is attached by benthos and to determine its corresponding degree of attachment. Compared with the other techniques, experiment results show that the proposed method can diagnose the blade attachment with higher accuracy.
Optimization of Mudaraba Sharia bank finance through agency theory perspective
Authors: Jasmin Djafar , Moeljadi M. , Djumahir  , Djazuli Atim
Published: November 2018

This study aims to analyze the implementation of mudaraba financing at Sharia banks, to consider the relationship between a principal and an agent in mudaraba financing at Sharia banks, and to explore efforts to optimize the implementation of mudaraba financing at Sharia banks.This research was conducted at the Bank Muamalat Ternate Branch. The study used a qualitative method of single case study approach. The analysis used is an interactive model developed by Miles and Huberman. Research result exhibits the following:1) The implementation of mudaraba financing was not in accordance with sharia implementation requirement, because there is still a gap in the income sharing system that causes the contract of mudharabah financing cannot be continued.2) A principal has more information than an agent, because the agent has limited information especially in terms of that about cooperation instrument (mudharabah financing), while the principal is way more about data on that cooperation instrument.3) Optimizing the implementation of mudaraba financing is needed by improving mudaraba financing governance. It is conducted by assigning consultants in mudaraba financing. The consultant has an active role and formally is directly involved in the mudharabah financing, but its characteristic only gives consideration and advice to shahibul maad and mudharabah as the key player in the mudharabah financing.
Effects of sertraline on cognitive function in patients with unipolar depressive disorders
Authors: Akhapkin R. V. , Fedorova A. I. , Faizulloev A. Z. , Emelin K. E.
Published: November 2018

Cognitive disfunction in depressive disorders have become a relevant aim of research in recent years. At the same time, the question of the influence of psychopharmacological drugs on the cognitive functioning of patients with depression also retains its significance. The article presents the results of a prospective study of the effect of sertraline on cognitive functions in patients with nonpsychotic unipolar depressive disorders. The study included 36 patients who received sertraline monotherapy for at least 12 weeks. The dynamics of depressive symptoms was assessed by the MADRS and HAM-D scales. The study of cognitive functions included memory testing (memory for faces), attention (Landolt rings), reaction time (sensorimotor reaction), psychomotor (tapping test) and executive functions (Stroop test, stress test, reaction to a moving object) with the help of the computer psychodiagnostic complex «Multipsychometer-05». The cognitive profile of the studied patients was characterized mainly by deficit of executive and psychomotor functions. The index of psychomotor activity significantly correlated with the severity of depressive symptoms. The use of sertraline contributed significantly to the reduction of depressive symptoms, as well as to the improvement of almost all the studied parameters of the cognitive profile, including memory, attention, reaction rate, psychomotor and performance functions.
The effect of sleep disorders on health and the possibility of correction of sleep disorders
Authors: Tsenteradze S. L. , Poluektov M. G.
Published: November 2018

Treatment of insomnia is an important medical and social problem due to its widespread prevalence and significant negative impact on human health. The state of chronic cerebral hyper-activation, which has cognitive, electrophysiological and metabolic manifestations, plays an important role in the development of insomnia. The sleep disorder has been proven to be a risk factor for the development of arterial hypertension, metabolic syndrome, immunodeficiency disorder and cognitive impairment. Nonmedicinal and medicinal products are used to treat insomnia. Cognitive-behavioural therapy may be effective as a psychotherapy.  Non-benzodiazepine GABA-receptors agonists are most often used to treat chronic insomnia and histamine receptor blockers to treat acute insomnia among the other drugs of this group.
Nonsteroidal anti-inflammatory drugs in therapeutic practice: nimesulide in focus
Authors: Ketova G. G. , Barysheva V. O.
Published: November 2018

The article presents the findings of questionnaire-based survey on the use of non-steroidal anti-inflammatory drugs conducted by the Chelyabinsk practitioners. It discusses the main indications for use of NSAIDs. The authors outline the key issues of the choice of drugs from the NSAID group, taking into account efficacy, safety and area of intended use. They also present the findings of the latest research studies conducted in Russia and abroad on the issues of efficacy, safety, epidemiology of the use of NSAIDs and paracetamol.
Significance of serum procalcitonin for differentiating infections from rheumatic diseases
Authors: Tarasova G. M. , Belov B. S. , Dilbaryan A. G. , Bukhanova D. V. , Glukova S. I.
Published: November 2018

Differentiation between flare of a rheumatic disease (RD) and the development of infectious process is often extremely difficult due to the similarity of clinical and laboratory manifestations, as well as their lack of specificity.

Objective of the study: to assess the significance of procalcitonin (PCT) test as a specific marker of generalized and local infection in patients with RD, and also to determine its role in assessing the inflammatory process activity in various RDs.

Material and methods: The case records of 145 patients (101 women , 44 men,  age of 3–79 years), who were undergoing inpatient examination and treatment at Nasonova Research Institute of Reumatology, were examined during the retrospective study. The serum PCT level was determined by the quantitative electrochemiluminescence method using  the Cobas E 411 analyzer (Roshe, Switzerland).

Results: The infectious process was diagnosed in 85 patients, the generalized one in 13 and the local one in 72. Local infections were divided into those with the light course – 41 and with the severe course – 31. In patients with generalized infection, the PCT level exceeded 2.0 ng/ml in 77% of cases and  in 10.0 ng/ml in 46.2% of cases.  Median (Me) PCT was 3.6 [2.26; 10.5] in the group with generalized infection. Me PKT exceeded the threshold values   and amounted to 0.49 [0.19; 1.5] ng/ml in the case of a local infection with the severe course,  PCT indices did not significantly differ from those of the group without infection (Me = 0.13 [0.08; 0.25] and 0.09 [0.06; 0.18 ] ng / ml, p> 0.05).with a local infection of the lungs, The maximum values   of PCT in the absence of infection and with a high activity of the rheumatic process were detected in patients with Adult-onset Still’s Disease (AOSD) – Me = 0.26 [0.10; 0.61] ng/ml, moderate increase was detected in patients with systemic-onset juvenile idiopathic arthritis (JIA)– Me = 0.2 [0.14, 0.24] ng/ml, juvenile rheumatoid arthritis (JRA) – Me = 0.2 [0.1; 0.26] ng/ml, systemic lupus erythematosus (SLE) – Me = 0.19 [0.11, 0.39] ng/ml.

Conclusions: Determining PCT level undoubtedly contributes to the diagnosis of generalized infections, and differential diagnosis of systemic RD from the infectious process. Further research is required to determine the PCT threshold value for various RDs.
Odnawialne źródła energii jako szansa na stworzenie proekologicznego wizerunku jednostki samorządu terytorialnego
Authors: Szlufik Martyna , Sasinowski Mateusz
Published: November 2018

W artykule została poruszona kwestia obowiązku samorządu terytorialnego dbania o środowiska naturalne. W tym celu jednostki samorządu terytorialnego powinien wykorzystywać najlepsze dostępne techniki, a więc m.in. alternatywne źródła energii. Odnawialne źródła energii zostały ukazane w kontekście zasad ogólnych wspólnotowegoprawa ochrony środowiska. Zgodnie z zasadą integracji polityki ochrony sektorowej z polityką ochrony środowiska, sektor energetyczny nie powinien szkodzić środowisku naturalnemu. Zasada prewencji wymaga działań zapobiegających zanieczyszczeniom powietrza, z kolei zasada ,,zanieczyszczający płaci” wprowadza kary za szkodliwą emisję.Zgodnie z zasadą wysokiego poziomu ochrony w każdym działaniu należy mieć na uwadze ochronę przyrody, a zasada usuwania szkód u źródła promuje stosowanie technologii czystej produkcji. Omówione zostały też zasady zrównoważonego rozwoju oraz partycypacjipublicznej, stanowiące podstawę zarówno ochrony środowiska, jak i udziału obywateli w decydowaniu o nim. Kolejna część artykułu dotyczy związków odnawialnych źródeł energii z samorządem terytorialnym na gruncie prawa krajowego w oparciu o polskie akty prawne, znajduje się tam też opis energetyki obywatelskiej z jej zaletami, sposobamifinansowania, a także z przykładami zarówno z Polski, jak i z krajów UE.
Dokument elektroniczny w jednostkach samorządu terytorialnego
Authors: Szymczuk Monika
Published: November 2018

W artykule zostanie opisane pojęcie dokumentu elektronicznego, w szczególności omówione będzie zastosowanie dokumentu elektronicznego w jednostkach samorządu terytorialnego. Przedstawiona zostanie potrzeba wprowadzenia elektronicznej administracji, w tym dokumentu elektronicznego oraz opisane będą unormowania prawne, które wpłynęły na rozwój i zainteresowanie tym tematem. Dla usprawnienia działania pracy jednostek samorządu terytorialnego ważne jest wprowadzenie najnowszych rozwiązań technologii informacyjno komunikacyjnej, dlatego dla poznania pojęcia i roli dokumentu elektronicznego w organach administracji publicznej, niezbędne jest określenie korzyści i zagrożeń związanych z nowymi rozwiązaniami e-administracji, w tym dokumentacją elektroniczną. Przy stosowaniu mechanizmów elektronicznych organy jednostek samorządu terytorialnego powinny przestrzegać zasadd powszechności i bezpieczeństwa, które również zostaną opisane w artykule.
Települési villamos energia önellátás meghatározásának módszerei
Authors: Kulcsár Balázs
Published: November 2018

A technológiai fejlődéssel elérhető közelségbe került az energiaváltás gondolata. Az átállás a fosszilis energiahordozókról a megújuló energiaforrásokra jelenleg területi kiterjedés kérdése, vagyis települési regionális vagy globális szinten érhető el. Jelen tanulmány, a települési szinten megvalósított 100%-ig megújuló forrásokra támaszkodó rendszerek módszertanát vizsgálja. A nemzetközi szervezeteken és esettanulmányokon keresztül rendszerezi a teljes megújuló alapú energiaellátáshoz vezető út módszereit, valamint vizsgálja meg ez alapján a magyarországi településállomány önellátottsági szintjét, sajátos módszereket alkalmazva.
Algoritmizálás játékosan
Authors: Vámosi Attila
Published: November 2018

Az EFOP–3.6.1–16–2016–00022 számú, „Debrecen Venture Catapult Program” elnevezésű pályázat „Műszaki kutatói kapacitás bővítése, kutatási szolgáltatások fejlesztése, tudásnégyszög kiépítése a mérnökképzésben” című alprogramjában alakult egy „Mérnöki és innovációs készségeket fejlesztő kutatócsoport”. A kutatócsoport vállalta, hogy készségfejlesztő foglalkozásokat dolgoz ki középiskolások számára matematika, fizika, ábrázoló geometria és informatika témakörökhöz kapcsolódóan. Jelen cikk a számos kifejlesztésre került foglalkozás közül a „Játékos algoritmizálás” című foglalkozást mutatja be, mely foglalkozás során számítógépes játékkal játszva fejlesztjük a diákok algoritmizálási készségét.
Gamification in programming - A short introductory session in programming with online games
Authors: Ádámkó Éva
Published: November 2018

Nowadays computer science is a diversified discipline with a wide range of interdisciplinary applications. Because of that, teachers at primary or high schools unavoidably face the following problem: What are the most useful fields, topics and applications of computer science and programming, and how can we teach them to be motivating enough for a student from the Z generation. In this paper we give a possible answer for the question above by presenting a short introductory session in programming for students in primary and high school. Our primary aim with the above session is to motivate students to continue their studies in engineering higher education. We also present our experiences about two experimental classes here.
Improving the Work Breakdown Structure of the Plant Installation - Case: Asphalt Plant
Authors: Abujudeh Said
Published: November 2018

The improvement of the project management forced the industrial organizations to focus on using the project management techniques in their industry, to plan and control the workflow to achieve their targets, further to increase the satisfaction of their customers. One of the most common project management tools are used is the work breakdown structure (WBS), which provide a framework for the implementation of the project scope including project planning, scheduling, monitoring, control, and estimation. Depending on the top-down approach the project activities will be broken into smaller parts that can be measured and controlled during the project implementation. The well-defined construction of the structure contributes to making the project more realistic and visual. However, the misunderstanding of the project WBS among the project team creates deflection and misinterpretation of the project scope. The main issue of this research is to improve the WBS of the installation plan and develop a standard WBS for plant installation. The research was limited to Asphalt plant installation WBS as a case study to identify the weaknesses of the current WBS at the case company which leads to extra installation time and cost. The research is offering a template WBS based on the company logic, defining the frequent risks that affect the plant installation based on the WBS and suggesting a suitable response strategy by recommending a control framework to monitor and control the WBS schedule throughout all installation phases.
A kézben tartható fejlődés egy kkv szervezet lean alapja
Authors: Baksi Zsolt
Published: November 2018

A lean személetmódjának alapja a vevő, a veszteségek kiküszöbölése során az értékteremtés és hatékonyságnövelés mellett ez határozza meg a folyamat fejlesztéseinek irányvonalát. A lean sikeres kiépítése és fenntartása érdekében a bevonás és fejlesztés nélkülözhetetlen, azonban nem olyan egyszerű dolog, ahogyan a korábbi viselkedési normák és attitűdök megváltoztatása sem. A vizsgált vállalat is felismerte, hogy változtatásra van szükség, ugyanis a vállalat megnövekedett létszámállománya, illetve a termelés növekedése és a vele járó profit egyértelművé tette, hogy szükséges a szervezetfejlesztés. A szervezetfejlesztést SWOT elemzéssel indult, majd ezen mentén Ishikawa segytségével feltártam, hogy szükséges-e a LEAN alaklamzása a vállalatnál. Gemba révén pedig számba vettem a problémákat, majd kategórizáltam őket a fejlesztési pontok kijelölése érdekében.
Learning Curve Based Sigma Level Determination in Interrupted Non-Production Processes
Authors: Molnár Viktor , Metszosy Gabriella
Published: November 2018

The philosophy and methods of six sigma process development have been applied successfully since mid1980s, and the application of the six sigma concept in non-production processes has increased significantly in the last decade. In this paper processes that can be characterized by learning curves are modeled. The quality of such processes can be analyzed on the basis of the six sigma concept. In this paper two back office processes are analyzed. The processes are built up of simple repeated steps and incorporate some interruptions. The application of the model allows the calculation of the maximally permitted number of interruptions in the process if the preliminary determined norm is to be kept.