bluuebunny/crossref_metadata_2025 huggingface dataset:
Combined use of CROSS TCA and modified subcision with PRP administration for acne scars
Authors: Fiqri Ahmad , Mochtar Moerbono , Zulfikar Dendy
Published: July 2022

Background: Acne vulgaris is a skin disease that can cause permanent scarring. Various therapeutic options are available to treat atrophic scars, but combination therapy is still the best choice according to different types of scars in a single patient. Chemical reconstruction of skin scars (CROSS) trichloroacetic acid (TCA), modified subcutaneous incisionless (subcision), and platelet-rich plasma (PRP) can be used as a combination therapy to treat acne scars. Case Illustration: A 25-year-old man complained of acne scars on both sides of his face. Dermatologic findings were blackheads, icepick, boxcar, and rolling scars. Clinically he had moderate to severe acne scores. He was treated with a combination of CROSS TCA for icepick-type acne scars, modified subcision, and PRP injection for rolling and boxcar-type acne scars on both sides of the face. During treatment, the patient was given oral and topical antibiotics. The patient was followed-up after one month. It resulted in a good therapeutic response, which showed 25%-49% of Goodman and Baron’s classification, and a visual analog scale of 6. Discussion: CROSS TCA is a therapeutic choice for icepick-type acne scars with a simple, practical technique and provides a significant effect. Modified subcision is modified therapies from the previous Khunger subcision technique and a new alternative that can be applied to damaged tissue. This can maximally repair scarring, facilitate surgeon, provide avenues, and increase maximum PRP penetration. Conclusion: CROSS TCA with subcision and PRP are simple procedures that can be applied as an alternative therapy to acne scars with good therapeutic response. Keywords: CROSS TCA, PRP, scars, subcision
Allergen profile of facial ACD to cosmetics among patients at Tertiary Referral Hospital in Yogyakarta
Authors: Alfieri Alessandro , Pudjiati Satiti , Waskito Fajar , Indriastuti Niken , Febriana Sri
Published: July 2022

Background: Cosmetics are a part of life for most of the population and may cause allergic contact dermatitis (ACD), especially on the face, as the primary exposure of cosmetics is on the face area. Methods: This research was conducted retrospectively using secondary data. The research subjects and demographic data were taken from the registered list of patients at Dermatology and Venereology Outpatient Clinic Dr. Sardjito General Hospital with a clinical picture of facial ACD due to cosmetics. Patch tests were carried out from January 2017 to December 2020. Results: From three years period, 26 patients were diagnosed with suspected facial ACD due to cosmetics and underwent patch tests. Of the total 26 patients, 3 patients did not show any reaction to the patch test. On the 23 patients who had reactions on the patch test, there were 66 points on the skin that showed a reaction to allergens. Of the 66 points, 37 points gave a positive reaction picture, with the most common allergen causing the reaction being cobalt(II) chloride hexahydrate (n=4, 10.8%). Then, from 29 points that gave doubtful reactions, the allergen that caused the most reactions was potassium dichromate 0.5% (n=4, 13,8%). Conclusion: The allergens that most often give a positive or doubtful reaction on the patch test of this study are metal compounds (cobalt and potassium dichromate). This study only looks at the patch test that gives a reaction without looking at the clinical relevance related to cosmetics use. Keywords: cosmetics, facial allergic contact dermatitis, patch test
Analisis Penggunaan Model Discovery Learning Dan Pengaruhnya Terhadap Keterampilan Proses Sains Pada Pembelajaran IPA Di SMPN 41 Muaro Jambi
Authors: Listiani Listiani
Published: July 2022

Pada kurikulum 2013, peserta didik dituntut untuk aktif dalam pembelajaran. Salah satu model pembelajaran yang cocok memenuhi kebutuhan saat ini adalah model discovery learning. Berdasarkan model pembelajaran, pembelajaran diarahkan pada keterlibatan peserta didik secara aktif melalui kegiatan proses. Kegiatan proses didapat dari pengalaman melalui kegiatan percobaan, untuk mendapatkan kegiatan proses dibutuhkan suatu keterampilan yang disebut keterampilan proses. Keterampilan dalam melakukan aktivitas-aktivitas yang terkait dalam sains biasa disebut keterampilan proses sains (KPS) yang merupakan perangkat kemampuan kompleks yang diasa digunakan dalam melakukan penyelidikan ilmiah pada proses pembelajaran. Pada penelitian ini bertujuan untuk mengetahui penggunaan model pembelajaran discovery learning dan pengaruhnya model pembelajaran discovery learning terhadap keterampilan proses sains pada pembelajaran IPA kelas VII SMPN 41 Muaro Jambi. Penelitian ini dilakukan pada pembelajaran IPA khususnya materi kalor dan perpindahanya dengan jumlah peserta didik 30 orang. Metode penelitian ini menggunakan jenis penelitian concurren embedded mixed methods. Hasil penelitian penggunaan model pembelajaran discovery learning pada pembelajaran IPA di kelas VII SMPN 41 Muaro Jambi cukup mendapat respon yang baik dari peserta didik, dapat dilihat dari nilai tes pre-test dan post-test yang diperoleh nilai yang jauh lebih baik ditunujukan dengan nilai rata-rata pre-test 44,4 dan nilai rata-rata post-test 78,133. Model pembelajaran discovery learning pada pembelajaran IPA mempunyai pengaruh yang signifikan. Hasil perhitungn uji hipotesis dengan uji t berpasangan atau t-Test: Paired Two Sample For Means menunjukan thitung = -15,445 dan ttabel = -2,045. Kesimpulannya karena thitung > ttable maka Ho ditolak dan Ha diterima.
From the history of teaching psychology: the first soviet textbooks of the 1920 1930s
Authors:   Lobachevsky state university of Nizhny Novgorod, Stoyukhina Natalya Y. , Kostrigin Artem A. ,   Institute of philosophy of the Russian academy of sciences
Published: July 2022

The article analyzes soviet textbooks on psychology in the 1920 1930s till the Decree «On pedological perversions in the system of the People's Commissariat of Education» of July 4, 1936. The works of K. N. Kornilov, V. A. Artemov, N. A. Bernshtein, L. S. Vygotsky, N. F. Dobrynin, A. R. Luria, P. S. Lyubimov, S. M. Vasileisky, A. A. Gayvorovsky, S. M. Verzhbolovich, A. P. Boltunov and G. E. Shumkov are examined. Their textbooks, practicums, anthologies and manuals are discussed. The main core of educational publications were works written by employees of Moscow state institute of experimental psychology under the guidance of K. N. Kornilov. This was reflected in the theoretical and methodological principles on which the authors stood when developing their textbooks: in many of them the concept of reaction was central, and the interpretation of various mental phenomena was carried out from the standpoint of reactology. The second group of educational works used other psychological approaches common at that time — foreign Gestalt psychology, pre-revolutionary Russian empirical and experimental psychology, Soviet reflexology. However, since the early 1930s and after the reactological discussion in 1931, educational developments within the framework of reactology and other original psychological trends were practically curtailed. The last textbook of the period under study, published by K. N. Kornilov in 1934, became a kind of transition from the period of theoretical and methodological pluralism in Soviet psychology to a homogeneous field of psychological science and education based on Marxism. Consideration of Soviet textbooks on psychology in the 1920 1930s allows analyzing not only the characteristics of psychological education of this period, but also determining their theoretical and methodological foundations, on which the teaching course or educational-methodological publication was built.
The Genetic Psychosocial Risk Instrument (GPRI): A Validation Study for European Portuguese
Authors: Gomes Pedro , Ferreira Tiago , Mena Matos Paula , Silva Eunice , Silva João , Esplen Mary Jane , M. D. Sales Célia
Published: July 2022

Introduction: Screening instruments specifically developed to identify genetic testing applicants who may need professional psychosocial support are much needed. However, there are no screening instruments validated for the Portuguese language. This paper presents the translation, adaptation, and validation process of the Genetic Psychosocial Risk Instrument in a sample of 207 Portuguese applicants to genetic testing in the context of inherited cancer risk.Material and Methods: Participants were mainly female (84.06%), with a mean age of 40.08 (SD = 12.89) and were recruited from the Portuguese Oncology Institute of Porto. Confirmatory factor analysis was conducted to confirm the Genetic Psychosocial Risk Instrument factorial structure. Convergent validity was assessed with the Impact of Events Scale, the Clinical Outcome Routine Evaluation – Outcome Measure, and the Hospital Anxiety and Depression Scale.Results: A model composed by the factors ‘Internal Impact of Genetic Testing’, ‘External Impact of Genetic Testing’ and ‘History of Mental Health Concerns’ was confirmed. These factors showed good internal consistency, convergent and discriminant validity. The factor ‘Personal Loss to Cancer’ proposed in the Canadian and French versions did not converge. We propose excluding this factor from the European Portuguese version of the scale.Conclusion: The European Portuguese version of the Genetic Psychosocial Risk Instrument is a reliable and valid instrument, although more research is needed to effectively use it in routine clinical oncogenetic departments.
Lesiones de causa externa y su relación con el alcohol en pacientes atendidos en un hospital de emergencia de Lima, Perú
Authors: Villar Emily , Málaga Hernán , Falcón Néstor
Published: July 2022

Objetivo: Describir las características demográficas, temporales y espaciales de las personas con lesiones de causa externa (LCE) y la relación con el consumo y la disponibilidad de alcohol, ocurridos en el distrito y atendidos en un hospital de emergencias. Material y métodos: Estudio descriptivo retrospectivo de personas atendidas por LCE en el Hospital de Emergencias José Casimiro Ulloa en el periodo 2014-2016 y la información de la denuncia policial por los afectados, en la comisaría del distrito. Se determinó la asociación entre las variables demográficas, temporales y espaciales con el tipo de LCE y la presencia de alcohol mediante pruebas de regresión logística. Resultados: Se encontró que era más probable la presencia de alcohol en un accidentado con LCE, cuando este era del sexo masculino en los días jueves a domingo. La contusión en una LCE en vez de una herida cortante, fue más probable cuando el accidentado era de sexo masculino, edades entre 15 a 38 años, la causa era una agresión, la ocurrencia del evento se producía entre las 00:00 a 18:00 horas, los días jueves a domingo y en los años 2014 y Geográficamente, la ocurrencia fue mayor en avenidas principales a no más de 500 metros de lugares donde se vendía y consumía licor. Conclusiones: La persona que va atenderse por lesiones de causa externa causadas como consecuencia de la violencia tiene una alta probabilidad de ser varón, además ocurren con mayor frecuencia los fines de semana y en avenidas principales en donde se puede usar un transporte público y no a más de 500 metros de lugares en donde se puede vender y consumir alcohol sin necesidad de ser residentes del distrito de ocurrencia, sin descartar que el consumo de alcohol pueda considerarse un factor de riesgo.
Repercusión familiar y apoyo social en familias de pacientes con lesión medular
Authors: Chávez-Cristóbal Olinda
Published: July 2022

Objetivo: Determinar si existe asociación entre la repercusión familiar y el apoyo social en familias de pacientes con lesión medular espinal. Material y métodos: Estudio observacional, descriptivo y relacional. El estudio se llevó a cabo en un instituto especializado de rehabilitación del Ministerio de Salud. La población de estudio fue 50 familias de pacientes con lesión medular, a quienes se les evaluó la repercusión familiar mediante el instrumento de repercusión familiar (IRFA) y el apoyo social mediante el cuestionario MOS de apoyo social. Resultados: El 44% de los pacientes y el 58% de los familiares tenían entre 30 y 59 años. El 34% de los cuidadores eran cónyuges del paciente, el 48% era familia de tipo nuclear y el 62% de las familias pertenecieron al nivel socioeconómico de pobreza extrema. El 78% de los pacientes tenían paraplejía y el 48% lesión tipo ASIA A. La repercusión global, fue elevada en 68% y con un sentido negativo en 94% de los casos. En el apoyo social emocional/informacional, instrumental, afectivo e interacción social positiva, se encontró una media de 27,8 ± 4,7 puntos; 15,2 ± 2,5 puntos; 11,3 ± 1,9 puntos y 12,8 ± 2,4 puntos, respectivamente. Se encontró relación entre el sexo del familiar (p=0,043), edad del paciente (p=0,013) y parentesco (p=0,014) con la repercusión familiar; sin embargo, no hubo relación entre las dimensiones del apoyo social y la repercusión familiar. Conclusiones: No hubo diferencias del apoyo social en los niveles de repercusión familiar de los pacientes con lesión medular espinal atendidos en un instituto de rehabilitación.
Models of Role-Structure in Project-Based Games for Children in Kindergarten About 5-6 Years Old
Authors: Wang Yingying , Zhao Li
Published: July 2022

In this paper we report on the use of project-based learning in teaching the children about 5-6 years old. We call it “Project-based game”. It’s a way of proceeding through the organization of mutual collaboration of children to solve the real problems of games, from which can excise children on transferring knowledge and problem-solving ability. Children work as a team. Each team member has the different role and task. So how to integrate resources to play a team advantage, and how to tap the maximum potential of each team member are particularly important. This study was trying to build a role of structural models for children to explain the relationship between the different roles in the project learning and reference for researchers. This study accomplished the following works:we interviewed normal teachers and children which from different classes, aware of the problems of grouping when teachers carry out the project game. Then we tracked and observed a number of project cases in kindergarten, designed the questions and tasks and collected a wealth of experimental data. Through the collation and analysis, we finally obtained significant achievement in this study “The role of structure model in project-based games for the children in kindergarten about 5-6 years old”.
A Machine Learning Prediction of Academic Performance of Secondary School Students Using Radial Basis Function Neural Network
Authors: Olabanjo Olusola , Wusu Ashiribo
Published: July 2022

Introduction: Academic success is primary goal of every student. It is described as the extent to which a student has successfully achieved his or her short and long-term educational goals. Several factors have been established to predict academic performance of students. Machine learning techniques have been employed in predicting students’ performance, but it has not been prevalent in developing countries like Nigeria and most studies did not consider class teachers’ end-of-the-year rating. Aim: The aim of this work is to develop a Radial Basis Function Neural Network (RBFNN) for prediction of secondary school students’ performance. Materials and Methods: We obtained data from school repository containing students’ raw score and classteachers’ rating from year one to year six. The data was labelled into pass or fail given the actual outcome of their examinations. Subjects were categorized into Mathematics, English and major, depending on the student’s specialization. Class-teachers’ ratings were also included in the dataset. The preprocessed dataset was used to train the RBFNN model. The impact of Principal Component Analysis (PCA) was also measured. Results: We set up four experiments in order to achieve our aim. The best result gave the sensitivity of 93.49%, specificity of 75%, accuracy of 86.59% and an AUC score of 94%. Other experiments gave a relatively low performance. Conclusion: This study helps students to get a projection of academic success even before sitting for the examination. This will also help parents and counsellors in knowing the direction of their counseling to each student. Teachers and parents should pay attention to class teacher ratings of the students as this is discovered to affect the prediction accuracy of their examination success.
Integrasi Perceived Security dan Promosi dalam Mendeteksi Perilaku Konsumsi Milenial Sorong di Era Digital: Sebuah Analisis Model UTAUT2
Authors: Yuliani Irma , Amin Muhammad
Published: July 2022

Perkembangan sistem digital dalam transaksi keuangan di indonesia tidak hanya terpusat di wilayah metropolitan saja. Sorong sebagai wilayah indonesia timur tampaknya juga memiliki potensi yang cukup besar sebagai wilayah dengan tingkat penetrasi internet yang tinggi. Penggunaan platform dompet digital di kota Sorong masih di dominasi oleh penduduk milenial. Penelitian ini bertujuan untuk menganalisis model UTAUT2 dalam mendeteksi minat milenial sorong menggunakan dompet digital dengan integrasi perceived security dan promosi. Penelitian ini termasuk penelitian survei dengan pendekatan explanatory study, yaitu berupaya untuk mengembangkan suatu model agar memperoleh model prediksi yang paling tepat. Data dalam penelitian bersifat primer yang dikumpulkan melalui kuesioner dan dianalisis menggunakan SEM – PLS (Structural Equation Modelling – Partial Least Square). Hasil penelitian menunjukkan bahwa variabel performance expectancy, facilitating condition, habit, perceived security, dan promosi berpengaruh signifikan terhadap minat milenial sorong menggunakna dompet digital. Sedangkan variabel effort expectancy, social influence, dan price value tidak berpengaruh terhadap minat milenial menggunakan dompet digital. Implikasi dari penelitian ini merekomendasikan adanya pengembangan fitur-fitur tertentu seperti fitur debit-kredit payment, user tutorial, serta penciptaan ekosistem digital yang kondusif dan inklusif untuk meningkatkan kepuasan konsumen.
Internal Torsion of the Knee
Authors: Qiao Yi , Zhang Xiuyuan , Xu Junjie , Xu Caiqi , Zhao Song , Zhao Jinzhong
Published: July 2022

Background:

Torsion of the lower extremities has been suggested to be a predisposing factor for patellar instability. However, no clear torsional factors have been clarified. This study aimed to elucidate the rotational geometry of the lower limb through segmental analysis in patients with patellar instability.

Methods:

Eighty-three patients with patellar instability were included. Computed tomography of the lower limb was acquired. Femoral and tibial torsion were measured in different segments. Femoral and tibial torsion in each segment was compared between the high- and normal-torsion groups to investigate which segment contributes the most.

Results:

All segments of femoral and tibial torsion except proximal femoral torsion showed significant differences between the high- and normal-torsion groups. The average proximal femoral torsion was 1.9° ± 7.1°, indicating that there was only slight torsion in the segment of the femoral neck. The angle between the femoral neck and the foot orientation in the normal-torsion, high-torsion tibial, and combined high-torsion femoral and tibial groups was 89.1° ± 12.0°, 81.3° ± 9.4°, and 98.2° ± 11.7°, respectively (p < 0.001), which suggested that the femoral neck remained nearly perpendicular to the foot orientation in the normal-torsion group. Shaft and distal femoral torsion contributed the most to total femoral torsion. For tibial torsion, from distal to proximal, internal torsion of both the proximal and distal segments contributed to the high torsion. There was no significant difference between distal femoral torsion and proximal tibial torsion, which suggested that, rather than the distal femur rotating internally on its own, the distal femur and the proximal tibia simultaneously rotated internally.

Conclusions:

In patients with patellar instability, torsional deformity occurs along the length of the tibia and in the shaft and distal segments of the femur. The comprehensive embodiment of lower-extremity malrotation is an internal rotation deformity of the knee.

Clinical Relevance:

This study elucidated the rotational geometry of the lower limb through a detailed segmental analysis in patients with patellar instability. It could serve as a theoretical basis for choosing a derotational osteotomy site and may be a reference for additional clinical research.
Modular Fluted Tapered Stems for Periprosthetic Femoral Fractures
Authors: Hannon Charles P. , Sheehan Kevin P. , Duong Stephanie Q. , Yuan Brandon J. , Lewallen David G. , Berry Daniel J. , Abdel Matthew P.
Published: July 2022

Background:

Modular fluted tapered (MFT) stems have advanced treatment of Vancouver B2 and B3 periprosthetic femoral fractures, but series to date have been limited with respect to cohort size and follow-up duration. The purpose of this study was to determine implant survivorship, radiographic results, complications, and clinical outcomes of Vancouver B2 and B3 periprosthetic femoral fractures treated with MFT stems in a large series of patients.

Methods:

We identified 171 Vancouver B2 (109) and B3 (62) periprosthetic femoral fractures treated with an MFT stem between 2000 and 2018 using our institutional total joint registry. The mean age was 75 years, 50% were female, and the mean body mass index was 29 kg/m2. The median stem diameter was 18 mm and median stem length was 210 mm. The cumulative incidences of revision and reoperation with death as the competing risk were calculated, radiographs were reviewed, and clinical outcomes were evaluated using the Harris hip score (HHS). The mean follow-up was 5 years.

Results:

The 10-year cumulative incidence of any revision was 10%. There were 17 revisions, of which only 3 were for the distal fluted portion of the MFT stem. Revision indications included periprosthetic joint infection (PJI) (n = 6) and dislocation (n = 11). The 10-year cumulative incidence of any reoperation was 15%. In addition to the above 17 revisions, there were 7 reoperations for superficial wound complications (n = 4), Vancouver B1 periprosthetic femoral fracture (n = 1), vascular occlusion (n = 1), and acetabular cartilage degeneration requiring an acetabular component (n = 1). Radiographically, there was 1 fracture nonunion. All unrevised MFT stems were radiographically well fixed. Subsidence of ≥5 mm occurred in 11%, but all implants were stable at the most recent follow-up. The mean HHS was 75 at 2 years (n = 71).

Conclusions:

In this large series of 171 Vancouver B2 and B3 periprosthetic femoral fractures treated with MFT stems, we found that such constructs were associated with a high rate of fracture healing and provided extremely reliable and durable implant fixation, with no revisions for aseptic loosening. Dislocation and PJI were the most common complications.

Level of Evidence:

Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Ecolodge y centro de investigación educativa ocupacional agropecuario: Adaptación de los sistemas constructivos tradicionales y uso de las energías renovables en los sistemas constructivos convencionales para el distrito de Huallanca-Áncash
Authors:   , Marquez Rene Sanie Lizeth
Published: July 2022

En la zona andina del Perú, se ha identificado que uno de los problemas más recurrentes en las últimas décadas, es que los sistemas constructivos tradicionales con materiales propios como adobe, piedra, y otros, han sido dejados de lado por sistemas constructivos convencionales como el concreto armado y hormigón, perdiendo las construcciones sostenibles e identidad de ellas. Esta tesis analiza la posibilidad de armonizar ambos sistemas en nuevas edificaciones de Huallanca - Ancash, incluyendo el uso de energías renovables aprovechables. Se aplicaron encuestas para conocer las características de la vivienda, economía y el turismo, fichas de observación de viviendas, y análisis documental de casos similares analizando las dimensiones tipológicas, de uso, sistemas constructivos y energías renovables. Se concluye que ambos sistemas pueden aplicarse en un solo proyecto, combinando estructura de concreto con el tapial y la madera laminada, con estrategias como edificios semienterrados, techos verdes, además la utilización de las energías renovables, generando un proyecto autosostenible. Se deben incluir criterios de manejo de topografía en montaña. Por lo tanto, se propone, un ecolodge cercano a la zona urbana de Huallanca combinando con un centro de investigación educativa ocupacional agropecuario, que potencie turismo vivencial aprovechando el paisaje andino, y aumente las capacidades de la población, fortaleciendo la ganadería y agricultura en altura, complementando con la experiencia vivencial de los turistas. Este proyecto materializa la integración de los sistemas constructivos tradicionales, convencionales y la eficiencia energética a partir del trabajo volumétrico, la materialidad y los detalles. En conclusión, este proyecto busca ser un ejemplo de arquitectura sostenible en la sierra del Perú.
Cuantificación de las nanopartículas del exosoma de célula madre del cáncer mamario triple negativo para estudios biológicos y proteómicos
Authors:   , Choque Matos Jorge Alex Alfredo
Published: July 2022

Introducción. Las células madre del tumor mamario triple negativo (CSC-TMTN) producen secretomas cuyas nanopartículas pueden ser biomarcadores, pero no se conoce su frecuencia y concentración en líneas celulares. Materiales y Métodos. La concentración y frecuencia de nanopartículas del secretoma de CSC de las líneas MDA -MB-231 y MDA-MB-436 del TMTN, se determinó mediante la técnica TPRS usando el sistema qNano, previamente se concentró mediante filtros de centrífuga Amicon™ (Sigma-Aldrich®, MO, USA) Ultra-15 Centrifugal Filter con un corte de peso molecular de 30kDa. Resultados. La mayor frecuencia de nanopartículas se encuentra en el rango de 0-200 nm para las CSC-MDA-MB-436, en tanto que para las CSC-MDA-MB-231 se encuentran entre 201-500 nm. La concentración fue mayor en las células madre del cáncer y su respectiva línea de origen MDA-MB-436. Conclusiones. Hay diferencias en frecuencia y concentración de nanopartículas del secretoma de las CSC, lo que permitirá estudios diferenciales para buscar biomarcadores.
Evaluación de la biodisponibilidad de mercurio en el ecosistema del río Ichu en Huancavelica, afectado por contaminación difusa
Authors:   , Malca Michaud Juan Diego
Published: July 2022

El objetivo del trabajo de investigación fue evaluar la biodisponibilidad de mercurio en el ecosistema del río Ichu–Huancavelica afectado por contaminación difusa. La metodología aplicada se enmarca en el protocolo nacional para el monitoreo de la calidad de los recursos hídricos superficiales, las muestras de sedimento extraídas del lecho del río fueron colocada en frascos de plástico rotulados, la vegetación ribereña fue recolectada en forma integral considerando raíz; tallo; hojas y flores; utilizando bolsas de polietileno para su seguridad, la muestra de peces [trucha arcoíris (Oncorynchus mykiss)] fue adquirida en la “Piscigranja” consideraciones el mayor tamaño. Todas las muestras fueron trasladadas al laboratorio CERPER en la ciudad de Lima para realizar los análisis de mercurio. Los resultados de mercurio en promedio fueron, agua: PM–01 y PM–02 <0.0002 mg/L; PM–03 0.004 mg/L y PM–04 0.0005 mg/L, sedimentos: PM–02 37.46 mg/kg y PM–03 34.72 mg/kg, vegetación ribereña: PM–02 0.04 mg/kg y PM–03 0.22 mg/kg, peces: PM–04 0.019 mg/kg.
New data from the first discovered paleoparadoxiid (Desmostylia) specimen shed light into the morphological variation of the genus Neoparadoxia
Authors: Matsui Kumiko , Valenzuela-Toro Ana M. , Pyenson Nicholas D.
Published: July 2022

Desmostylia is an extinct clade of marine mammals with two major sub-clades, Desmostylidae and Paleoparadoxiidae, known from Oligocene to Miocene strata of the North Pacific coastline. Within Paleoparadoxiidae, three genera have been identified: Archaeoparadoxia, Paleoparadoxia, and Neoparadoxia. The latter taxon is the geochronologically youngest palaeoparadoxiid and characterized by a comparatively larger body size, although it is known only from a few specimens within a short temporal and geographic range. Here we report the discovery of an isolated tooth identified as Neoparadoxia cf. N. cecilialina, constituting only the second individual specimen of Neoparadoxia with preserved dentition yet reported. This specimen was collected near Corona, California, USA, and we attribute it to the “Topanga” Formation, becoming the first record of Neoparadoxia from this unit. While the exact geographic locality was not properly recorded for this specimen when it was collected in 1913, we establish two potential localities based on the associated hand-written museum label and new stratigraphic information. Although this specimen wasinitially identified as Desmostylus hesperus, it was collected 10 years before the first named paleoparadoxiid from Japan. This new occurrence data adds to interpretations of marine mammal assemblages, especially in Southern California where paleoparadoxiids co-occur with desmostylids and sirenians.
Computational System for Prediction of the Vacuum Degree of Vacuum Glass
Authors: GASTRO OMARY
Published: July 2022

The heat transfer characteristics of vacuum degree and the influence of the vacuum degree of vacuum glass on unit operations for predicting the vacuum degree were investigated. In this study, we designed and developed a set of intelligent detection systems using intelligent algorithms that comprised a model for predicting the vacuum degree of vacuum glass. Using wireless temperature detection in an intelligent detection system was convenient for measuring temperature data. First, the model utilized a backpropagation neural network (BPNN) to predict and infer temperature data. Furthermore, we developed a software package implementing the proposed BPNN-based model in MATLAB and verified that it could predict the vacuum degree of vacuum glass. The proposed system created a precedent for using intelligent algorithms to establish a model to predict the vacuum degree of vacuum glass with additional computer software to improve its convenience for users. Using the core theoretical module of the system, BPNN, and the appropriate intelligent algorithms, we obtained an absolute error within 1.5 Pa using the model and learnt that it was good for quick vacuum prediction.
An Investigation of Several Models for Machine Learning Based Automated Essay Grading System
Authors: R Pradeep , M Kowsalya
Published: July 2022

Automated Essay Grading (AEG), formerly known as scoring systems, is no longer a myth. These AI systems are a boon to the educational sector, as teachers often have difficulty evaluating students' essays. It's a real hurdle to examine a large number of student articles in a short period, even while providing feedback. However, AEG systems can now effortlessly evaluate human-written (not handwritten) essays. One of the best instances of its application is the TOEFL exam. Student’s essays are graded by both a human and an automatic essay grading system. Many of the characteristics that distinguish good and bad writing, as well as many of the linguistic, cognitive, and other skills that underpin human potential for both reading and writing, might be explained using AEG. Teachers frequently use free-text questions to assess students' overall competence, which has led to an increased focus on clever auto-grading systems to reduce the grading load on examiners. A revolutionary automatic essay scoring system based on Machine Learning and Python is presented in this work. The suggested method, in particular, encodes an essay as sequential embedding’s and uses a bi-directional LSTM to capture semantic information. Meanwhile, the method builds attention for each essay so that the network can learn to correctly focus on genuine material in an article, which can also provide reasonable evidence of the prediction outcome. The public essay set provided in Kaggle's Automated Student Assessment Prize was used for training and testing.
Fixing usability smells of mobile apps: A multi-objective early refactoring recommendation approach
Authors: Soui Makram , Chouchane Mabrouka , Mansouri Nesrine
Published: July 2022

Usability is crucial for mobile app success. Usability evaluation and correction of Mobile User Interface (MUI) is fundamental phase to discover the usability smells and improve its quality. However, it continues to be a hard, expensive, and generally it is ignored. Several existing works depend on a subjective assessment of usability defects which relies on users’ feedback, that leads to time-consuming, human-centric, and error-prone task. Hence, recent works proposed tools for collection and analysis log user interaction when using the mobile application to understand user behavior and identify usability smells. But, these tools treat the defects with the same importance and rarely propose recommendations to help evaluator to improve their MUIs. It still also needed to identify concrete usability defects and fixed riskiest usability smells. In addition, most existing methods proposed to assess the usability of once the applications has been developed, which led to a lot of reworking by the designer because these changes can affect the development phases.In this paper, we propose an automated approach based on correction rules which combine literature evaluation metrics with usability smells to define recommended refactoring of MUI.To this end, we consider this refactoring recommendation as a multi-objective optimization problem. The purpose of this optimization is to maximize the number of refactoring per individual while minimizing the number of features per rule, the number of rules by solution, the misclassification rate, the information gain and improving the MUI quality in terms of guidance and cohesion coverage and minimizing the complexity of MUI. Moreover, we leaded a comparative study of four evolutionary algorithms to solve this optimization problem. The results prove the efficiency of the IBEA in terms of generating the most accurate refactoring rules with an average of 0.92 of AUC.This paper applied an evolutionary algorithm to recommend the best refactoring operations to enhance the quality of MUI. The results are promising. Our search-based algorithm successfully searches the best trade-off between eight objectives and recommending the most accurate refactoring rules compared with other studied algorithms.
Coverage of different kinds of paper by varied treatments with chitosan/montmorillonite nanocomposite layer
Authors: Zhou Pingyan , Yi Jing
Published: July 2022

The barrier of paper against water vapor and oxygen can be improved by coating chitosan/montmorillonite nanocomposite on the surface of base paper. The high coating layer coverage is the most important factor which affects the barrier property of paper. The effects of different kinds of base papers and drying conditions on the coverage of chitosan/montmorillonite nanocomposite layer were researched in this paper. The coverage of montmorillonite/chitosan nanocomposite was characterized by the scanning electron microscope and the optical contact goniometer. The water permeation was verified by the penetration dynamics analyzer. It was found that the base paper with a smooth and tight surface had the high coating layer coverage, resulting from little water penetration into the base paper. High drying temperature and rapid drying speed benefited to increase the coverage of chitosan/montmorilonite nanocomposite and form a uniform coating layer on the surface of base paper.
Nutritional Status of β-Thalassemia major patients
Authors: Lidoriki Irene , Stavrou George , Schizas dimitrios , Frountzas maximos , Fotis Lampros , Kapelouzou Alkistis , Kokkota Smaro , Tsaousi Georgia , Fyntanidou Barbara , Kotzampassi Katerina
Published: July 2022

Background: Patients suffering from thalassemia have impaired body composition and increased nutritional risk. To assess body composition and vitamin D levels of thalassemic patients in relation to nutritional risk.Methods: A total of 67 consecutive adult patients who were diagnosed with thalassemia major and followed a regular blood transfusion scheme were included in this study. Demographic and clinical data were registered for each participant. Blood samples were collected to assess 25-hydroxy-vitamin D (25-OH-D) levels. The assessment of patients’ nutritional risk was based on the Malnutrition Universal Screening Tool. Body composition assessment was based on bioelectrical impedance analysis.Results: Eleven patients (16.4%) and five patients (7.5%) were at moderate and high risk for malnutrition, respectively. Moreover, 86.6% of patients had low fat-free mass index (FFM) and 74.6% of patients had high fat mass (FM) index. The prevalence of sarcopenic obesity and 25-OH-D deficiency was 64.2% and 92.2%, respectively. Medium and high-risk patients had significantly lower BMI (18.81 ± 1.29 vs 23.90 ± 2.65 kg/m2, p<0.001), lower FFM index (12.80 ± 1.38 vs 14.19 ± 1.89 kg/m2, p=0.009) and lower FM index (5.97 ± 1.86 vs 9.70 ± 2.70 kg/m2, p<0.001) than their low-risk counterparts.Conclusions: Adult patients with β-thalassemia major had low levels of vitamin D and altered body composition, presenting with increased adiposity, low levels of lean body mass and high rates of sarcopenic obesity. Timely detection of patients at risk could lead to prioritization of patients that could benefit from nutritional interventions.
A rare complication post-hysterectomy for fibroids: a case report and literature review of Pulmonary Benign Metastasising Leiomyoma
Authors: Malina Madeleine , Magro Michael , Rathod Kunal
Published: July 2022

PurposeBenign Metastasising Leiomyomatosis is a rare complication of a common gynaecological condition, often requiring multidisciplinary team input. No guidelines exist for its management. We aim to highlight an unusual case and summarise international practice of investigation and management from existing literature, to facilitate better recognition and management in the future. MethodsWe present a challenging case of progressive pulmonary BML in a woman with previous lung cancer. An extensive Pubmed search was performed using search terms: benign, metastasising, metastasizing, parasitic, leiomyoma, leiomyomata, leiomyomatosis, fibroid and fibroids. All English papers available in free text were reviewed for the literature review.Results80 relevant papers reporting 123 cases were included. We report common demographics, gynacological backgrounds and presenting symptoms of the women. Diagnosis involved CT imaging in 96% of cases, histopathology in 93% and immunohistochemistry in 83% with the most common markers used being ER, PR, SMA and Ki-67. PET scan was performed in 24%. We summarise also the management options, including an overview of current hormonal treatment options, and follow-up regimes which typically involves regular CT-scans. ConclusionPulmonary BML is a benign condition but it presents similarly to lung cancer, making our case especially complex. Malignancy must therefore always be a differential diagnosis. Management is individualised as shown in our review but may be expectant, medical or surgical, with a strong emphasis on follow-up.
WITHDRAWN: Rethinking Urban Planning from the Perspective of Nature-based Stormwater Runoff Management in Hawassa City, Ethiopia
Authors: Gerezgher Tikabo Gebreyesus , Habtemariam Kumlachew Yeshitila , Mengistu Aramde Fetene , Jauregui Cristina Herrero , Tesemma Mesele Negash
Published: July 2022

A considerable area of land has been turned into a built surface due to urbanization in Ethiopia. Storm-runoff is the impact of land conversion into built areas, which is a threat every rain season in Hawassa city. GI-based urban planning plays a prominent role in runoff management. However, the potential benefit of GI remains unexplored in Ethiopia. This research aimed at evaluating the effectiveness of GI to alleviate stormwater runoff that cities have been suffering from. The i-Tree Eco model with pre-stratified random sampling techniques was employed to analyze the hydrological benefits of GI by considering the vegetation structural variables. The ArcGIS was further used to demonstrate the spatial distributions of annually avoided runoff and potential sites across the study area. The study shows that the total number of trees in the study area is 576,224, which contributes to 20.7% of tree coverage in the city. These trees annually intercepted 1,376,132.8 m3 water and avoided 288,372 m3yr-1 runoff, and in turn economically valued at $680,558 USD. However, the GI elements had different runoff reduction efficiency, according to the morpho-functional characteristics of tree species. GI types with large trees, high leaf area, and high number of broadleaved trees were more efficient. Stormwater runoff could be maximized through the incorporation of adequate GI coverage at the planning stage and proper execution on the ground. Hence, this research is expected to make planners and policymakers rethink the integration of GI with the spatial planning of cities in Ethiopia.
Study of Fano resonance and its application in MIM waveguide using a k-shaped Resonator
Authors: Fan Haopeng , tian jinping , Yang Rongcao
Published: July 2022

In this paper, a plasmonic MIM waveguide consisting of a k-shaped resonant cavity is designed, which can support three Fano resonances. The physical mechanisms behind the multiple Fano resonances are studied with the help of field distributions and the changes of geometric parameters. Further, by varying the refractive index of the dielectric medium filled in the air part of the waveguide, property of refractive index sensing is studied. The maximum sensitivity is up to 1250 nm/RIU and the maximum figure of merit is more than 4000. Eventually the slow-light effect is also investigated, and the results show that the maximum optical delay and the group index are about 0.05ps and 9.23, respectively. All the results may provide some fundamental references for the design of plasmonic optical waveguide devices, and it will also have potential applications in areas such as nanoscale refractive index sensing, slow-light effects, photonic device integration, and so on.
Nationwide study of risk factors for reoperation after surgical treatment for degenerative spinal disease in Poland
Authors: Słowiński Jerzy , Żurek Michał , Wypych-Ślusarska Agata , Krupa-Kotara Karolina , Oleksiuk Klaudia , Głogowska-Ligus Joanna , Kozioł Anna , Kozioł Milena
Published: July 2022

Background
The aim of the study is to evaluate the reoperation rate after surgical treatment for degenerative spinal diseases (DSD) in Poland and to identify risk factors for reoperation, including comorbidities and other variables.
Methods
A retrospective analysis of hospitalisations in 2018 that were reported to the National Health Fund (NHF) using ICD-10 codes: M43.1, M47, M48, M50, M51, M53 and Diagnosis Related Group (DRG) codes: A22, A23, A27, H51, H52, H53, H55. Reoperations were identified using the same codes provided that they were reported within 365 days after discharge. The analysis involved demographic factors and patient multimorbidity. A logistic regression model was then performed to assess risk factors for reoperation.
Results
In 2018, 38,953 surgical hospitalisations for DSD were reported. A total of 3,942 hospitalised patients (10.12%) needed reoperation within 365 days. Patients requiring reoperation were predominantly women (1.34:1) and the elderly (mean age: 56.66 vs. 53.24). The percentage of reoperations correlated with the multimorbidity rate (from 8.81–15.31%). The risk of reoperation was most increased by concomitant depression, neurological diseases, obesity and older age. The risk of reoperation was reduced by instrumented spinal surgery, operations in a neurosurgical department and hospitalisations other than day-surgery.
Conclusions
Reoperations within the first year of surgical treatment for DSD are common. Identification of risk factors for reoperation, including those related to the presence of comorbidities and the phenomenon of multimorbidity, can be an important tool in reducing the reoperation rate.
Insights into the mechanism of pre-mRNA splicing of tiny introns from the genome of a giant ciliate Stentor coeruleus
Authors: Chanarat Sittinan , Nuadthaisong Jirayu , Techawisutthinan Chanakan
Published: July 2022

Stentor coeruleus is a ciliate known for its regenerative ability. Recent genome sequencing reveals that its spliceosomal introns are exceptionally small. We wondered whether the multi-megadalton spliceosome has any unique characteristics for removal of the tiny introns. First, we analyzed intron features and identified spliceosomal RNA/protein components. We found that all snRNAs are present, whereas many proteins are conserved but slightly reduced in size. Some regulators such as Serine/Arginine-rich proteins are noticeably undetected. Interestingly, while most parts of spliceosomal proteins, including Prp8’s positively-charged catalytic cavity, are conserved, regions of branching factors projecting to the active site are not. We conjecture that steric-clash avoidance between spliceosomal proteins and a sharply-looped lariat might occur and splicing regulation may differ from other species.
Radiation-induced fibrosarcoma after breast-conserving surgery and radiation therapy for breast cancer: A case report and literature review
Authors: Hoshina Hideko , Kubouchi Kouichi , Tsutsumi Yutaka , Takei Hiroyuki
Published: July 2022

Background: Radiation-induced sarcoma (RIS) has a 10-year incidence of 0.2-0.27% and a poor prognosis. In particular, radiation-induced fibrosarcoma has been rarer, and its incidence is 2.6-3.7% of RIS.Case presentation: A 43-year-old woman with pT1N1M0 breast cancer underwent breast-conserving surgery, chemotherapy, radiation therapy eight years ago, and continued hormonal therapy. She complained of a hard mass palpated in her right axillary breast. Although we suspected local recurrence, core needle biopsy revealed atypical spindled tumor cells without mammary or epithelial markers. A diagnosis of fibrosarcoma was made via tumorectomy. She underwent additional enlarged surgery.Conclusions: We report a rare case of fibrosarcoma after breast-conserving surgery and radiation therapy. Fibrosarcoma after radiation therapy for breast cancer has been reported in 30 cases, including the present case. The dead and alive cases were not significantly different in terms of age, primary breast cancer, radiation dose, and following months. Patients with breast masses after radiation therapy should be suspected local recurrence and RIS.