bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of BRAF v600 mutation by single strand conformation polymorphism-PCR (SSCP-PCR) in patients with interstitial lung disease
Authors: Ejam Sura Salman , Abd Ali Israa Al-Humairi , Karbel Hadeel Abdulelah , Al-Jabory Mohammed Ali
Published: February 2024

Background:

Many studies demonstrating a high predominance of pulmonary disease among individuals with interstitial lung disease (ILD), genomic examinations have recognized and initiated mutations in proto-oncogene B-Raf (BRAF) among patients with lung malignant growth. To support our hypothesis of being ILD could show a more vital event for framing into bronchogenic threat BRAFV600E change was examined.

Objectives:

To inquire about the frequency of BRAF (V600E) mutation in ILD with the possible evaluation of the presence of BRAF V600 mutation and such parameters as patient’s age, gender, and histopathological type.

Materials and Methods:

From January 2017 to April 2019, a review study was led in a few confidential labs and the Teeba respiratory focus in Hilla city, Babylon region. Sixty patients with interstitial lung issues’ clarifying data were recuperated, formalin-fixed paraffin-embedded (FFPE) tissue portions were furthermore collected, all of the results were surveyed by three expert histopathologists, and the last attestation of the examination was done. Equivalent number (60) of healthy lung tissues were also involved and used as control tests for polymerase chain reaction review.

Results:

Only two (3.3%) of ILD tests harbored BRAF V600E change, all of them were between 41 and 50 years and were the usual interstitial pneumonitis (UIP) type.

Conclusions:

BRAF V600E mutation likely could be identified in ILD especially UIP. Prognosis of such patients with mutated BRAF gene should be observed.
Prevalence of coronary artery disease in patients with left bundle branch block and its association with risk factors hypertension and diabetes mellitus
Authors: Aljubawii Ameer Ahmad Abd AL-Ameer , Hussein Hussein Nassir , AL-Alwany Ameen Abdulhasan
Published: February 2024

Background:

Left bundle branch block (LBBB) is a common finding in electrocardiography, there are many causes of LBBB.

Objectives:

The aim of this study is to discuss the true prevalence of coronary artery disease (CAD) in patients with LBBB and associated risk factors in the form of hypertension and diabetes mellitus.

Materials and Methods:

Patients with LBBB were admitted to the Iraqi heart center for cardiac disease in December 2017 to the end of April 2021; all patients underwent coronary angiography and they are classified into three groups: group 1: patients with proximal left anterior descending artery (LAD) or mid-LAD and either left circumflex artery (LCX) or right coronary artery (RCA) with lesion consider significant if more than 70% stenosis of the artery, group 2: patients with either isolated LCX or RCA with lesion if more than 70% stenosis of the artery, group 3: patients with normal coronary artery.

Results:

The most important finding in this study is that the percentage of LAD artery lesions or two vessels disease was only 24.5%. Patients in group 1 showed a high prevalence of hypertension (77.6%), whereas in group 3, the prevalence of hypertension was 47.95%. In this study, the prevalence of diabetes mellitus in group 1 was high (62.2%), whereas in group 3, it was 32%.

Conclusion:

High prevalence of men with LBBB than women, and the prevalence of LBBB increases with age. Patients who had hypertension and diabetes mellitus with LBBB most likely had an ischemic cause of LBBB, but patients with LBBB had low ejection fraction (EF) 369 out of 400 patients (90%) had low EF.
Effect of breastfeeding on the HMGA2 single nucleotide polymorphisms in relation to first primary tooth emergence among Iraqi infants
Authors: Salih Shaimaa Thabit , Diab Ban Sahib
Published: February 2024

Backgrounds:

Breastfeeding provides a large group of functional components that improve the infant’s health and development.additionally, the impact of human milk and genetic variants on complicated outcomes has also been the subject of several gene–nutrition interaction studies. This could also play a key part in the kinship that exists between offspring and their parents.

Objectives:

The purpose of this study was to compare breastfeeding to infants who were fed formula in order to determine if human milk affected the timing of teething in relation to genetic polymorphisms.

Materials and Methods:

This study is a cross-sectional comparative study concerning genetic analysis with a prospective view concerning the timing of eruption. The chosen sample included 40 breastfed infants and 40 infants who consumed formula milk. It was compiled from Baghdad’s health centers. For the genetic analysis, DNA samples were obtained from saliva throughout the buccal swab. Standard DNA extraction and real-time PCR techniques have been used according to the manufacturer’s instructions for the Quick-DNA™ MiniPrep kit (catalog nos. D3024 and D3025). For the whole sample, clinical examination and monitoring for emerging teeth were performed using a particular criterion.

Results:

findings showed that there were highly significant differences between breastfeeding and early eruption time for the first primary tooth. Also, there was a significant association between single nucleotide polymorphisms in the heterozygous AG genotype and eruption time.

Conclusion:

The results of the current study may support the genetic influence of breast milk on early primary teeth eruption when juxtaposed with infants fed formula.
Single nucleotide polymorphism of IL-18 gene and resistin gene in children infection with Entamoeba histolytica
Authors: Al-Sultany Aseel Kariem , Al-Morshidy Kassim Abdulla Hamza
Published: February 2024

Background:

Human amebiasis is caused by Entamoeba histolytica, which is found in many tropical countries. E. histolytica infections are known to have a wide range of clinical consequences. Most infections are asymptomatic; some cause diarrhea and dysentery, and only a few cause extraintestinal consequences, including liver abscess. Single nucleotide polymorphisms (SNPs) are the most prevalent kind of sequence variation in genomes and are regarded as useful genetic markers for exposing the evolutionary history and common genetic variants that explain the heritable risk for common illnesses and effected in the progression of some infections.

Objective:

Investigation of gene polymorphism of the parameters (interleukin 18 [IL-18], resistin) most susceptible to parasitic infection.

Materials and Methods:

Stool samples were collected from patients who were attending the (Kerbala Teaching Hospital for children in the holy city of Kerbala), between February 2021 and January 2022. In total, 3748 samples of feces from children between the ages of 1 and 15 years from both gender were tested using both direct smear and acid-fast stain tests in addition to rapid test techniques. Five milliliters of blood were obtained from 25 patients infected with E. histolytica, as well as 5 mL of blood from 25 healthy youngsters (sample control).

Results:

The result showed the distribution of genotype of IL-18 SNPs in intestinal parasites patient in contrast to the control group; there is an increase in the level of IL-18 in some SNPs, resistin concentration was statistically significantly different between resistin gene polymorphisms.

Conclusion:

The IL-18 and resistin polymorphism can be considered one of the genetic factors responsible for the progression of E. histolytica infection.
The association between anti-glutamic acid decarboxylase IgG and hemoglobin A1C among newly diagnosed type 1 diabetes of some Iraqi children in Karbala City
Authors: Hadi Hiba Ali Al-Khadhi , Al-Masoudi Hayam Khalis , Mahdi Mohammed Salih
Published: February 2024

Background:

Type 1 diabetes mellitus (T1DM) is brought on by immune system dysfunction intolerance, invasion of beta cells by autoreactive immunological T cells, degradation of beta cell activity and survival, and extended exogenous insulin treatment. One of the circulation autoantibodies against antigens of pancreatic cell that produce insulin is glutamic acid decarboxylase (GAD IgG antibody) that indicate the stress and/or death of the islet cell in T1D. A blood glucose monitoring test called hemoglobin A1C (HbA1c) is used to determine the average blood sugar level over three months (February, March, and April of 2022).

Objective:

The purpose of this study is to assess the frequency of anti-GAD IgG and HbA1c in T1DM children, as well as their correlation.

Materials and Methods:

Seventy individuals with new-onset T1DM (confirmed by clinical signs, including increased urination, intense hunger, intense thirst, and abrupt weight loss, along with a random blood sugar test that is higher than 200 mg/dL and a fasting blood sugar test that is higher than 126 mg/dL) are male and female, ranging in age from 1 to 12 years. Blood was drawn for the biochemical and immunological tests (including HbA1c, fasting blood sugar, C-peptide, anti-islets antibodies, and anti-GAD antibodies).

Results:

Ninety-four percent of the T1DM patients had positive anti-GAD IgG with a mean concentration of 147 IU/mL, and 6% had negative anti-GAD IgG with a mean value of 9 IU/mL. At the same time, the findings of the current study’s calculation of HbA1c levels revealed that individuals with newly diagnosed T1DM had a total mean average of HbA1c of 10.53.

Conclusion:

Specifically in T1D that had arisen in extremely young children, autoimmunity was discovered to take part in the glycemic index expressed by glycated hemoglobin average.
Urokinase-type plasminogen activator receptor as a predictive marker for cardiac disease among type 2 diabetic patients
Authors: Mohammed Melak Saleh , Ahmed Hind Shakir
Published: February 2024

Background:

Type 2 diabetes mellitus is a progressive and chronic disease manifested by β-cell dysfunction and improved insulin resistance. Higher levels of urokinase-type plasminogen activator receptors have been found to predict morbidity and mortality among diabetic patients with cardiac disease.

Objective:

This study aims to explore the role of serum urokinase-type plasminogen activator receptor levels as a prognostic marker among type 2 diabetic Iraqi patients.

Materials and Methods:

A total of 70 type 2 diabetic patients (40 male and 30 female) (mean age: 46.20 ± 7.56 years) participated in this study; 35 patients were with cardiovascular disease and 35 were without cardiovascular disease; their ages range were 40–55 years. They were collected from Baghdad Teaching Hospital/Medical City, Baghdad, Iraq through the period from October 2022 to February 2023. Moreover, 30 individuals who were apparent healthy were selected as control group.

Results:

There was significant increase in blood glucose, lipid levels with their ratios, and C-reactive protein in diabetic patients as compared to the control. Also, the present results reveal high levels of urokinase-type plasminogen activator receptor (2500.72 ± 12.36 vs. 2255.32 ± 10.15) ρg/mL with OR = 1.80, 95% CI: 1.2, and P = 0.0001 in type 2 diabetic patients with and without cardiovascular disease, respectively, as compared to healthy control (229.00 ± 14.48) ρg/mL. Moreover, this study reveals that female patients had higher levels of serum urokinase-type plasminogen activator receptor as compared to the male patients.

Conclusion:

It demonstrated that urokinase-type plasminogen activator receptor levels reliably predict morbidity among type 2 diabetic patients presenting with symptoms suggestive of cardiovascular disease.
Local cOinage and Hospital Equipment Index (Lo Hei): projectile distance of Singapore coinage and healthcare-related equipment in a 3T magnetic resonance imaging scanner
Authors: Ong Shao Jin , Hallinan James TPD , Khoo Deborah , Hoon Desmond , Chia Koon Liang , Hang Joanne , Teo Lycia , Su Peijing , Ong Michael , Ang Bertrand , Quek Swee Tian
Published: February 2024

Introduction:

Modern magnetic resonance imaging (MRI) scanners utilise superconducting magnets that are permanently active. Patients and healthcare professionals have been known to unintentionally introduce ferromagnetic objects into the scanning room. In this study, we evaluated the projectile risk of Singapore coinage as well as some common healthcare equipment within a 3 T MRI scanner.

Methods:

A rig termed ‘Object eNtry Guidance and Linear Acceleration Instrument’ (ONG LAI) was custom-built to facilitate safe trajectory of the putative ferromagnetic objects. A ballistic gel target was utilised as a human tissue surrogate to estimate tissue penetration. The point at which objects would self-propel towards the scanner was named ‘Huge Unintended Acceleration Towards Actual Harm (HUAT AH)’.

Results:

Singapore third-series coins (10-cent to 1-dollar coins) are highly ferromagnetic and would accelerate towards the MRI scanner from more than one metre away. Cannulas with their needles are ferromagnetic and would self-propel towards the scanner from a distance of 20 cm. Standard surgical masks are ferromagnetic and may lose their sealing efficacy when they are worn too close to the magnet. Among the tested objects, a can of pineapple drink (Lee Pineapple Juice) had the highest HUAT AH at a distance of more than 1.5 m.

Conclusion:

Some local coinage and commonly found objects within a healthcare setting demonstrate ferromagnetic activity with projectile potential from a distance of more than 1 m. Patients and healthcare professionals should be cognisant of the risk associated with introducing these objects into the MRI scanning room.
Review for special issue: Corneal lamellar surgery: Present outcomes and future perspectives
Authors: Hamon Loïc , Weinstein Isabel , Quintin Adrien , Safi Tarek , Bofferding Max , Daas Loay , Seitz Berthold
Published: February 2024

Since the establishment of the first eye bank in the 1940s, their role has evolved to face new challenges. With the recent development of lamellar keratoplasties, eye banks play an even bigger role in the selection and preparation of donor tissues. The increasing number of keratoplasty techniques and the high demand for “ready-to-use” tissues are challenging eye banks to improve and develop new preparation techniques. Besides necessary examinations, new approaches of tissue analysis in eye banks allow a better/optimized selection of corneal tissues. These new challenges in tissue preservation, preparation, and selection are propelling eye banks into a new era of modern eye banking.
Pesimist gerçekçilik ya da teknolojinin amansız tahakkümü: Tech-noir
Authors: EROL Ece
Published: February 2024

Tür, geçmişten bugüne değin şiirden resme, tiyatrodan sinemaya kadar uzanan sanatsal ürünlerin sınıflandırılmasında kullanılagelmiş bir kavramdır. Yedinci sanat olarak kabul edilen sinemada da tür, müşterek nitelik, özellik ve öğelere sahip olan sinema eserlerinin belirli bir çatı altında bir araya getirilmesi olarak tanımlanır. Her ne kadar bu kümelendirme üzerinde mutabık kalınması, güç bir mahiyette olsa dahi bu durum, film üretim tatbikinin belirli biçimler ve şablonlar üzerinden gerçekleştirilmesini sağlamıştır. Bu türlerden biri olan ve 1940’lı yıllarda Hollywood’da ortaya çıkan film-noir, geçmişten günümüze kadar içinde bulunduğu zamanın ruhunu da benimseyerek ve değişip dönüşerek varlığını sürdürmeyi başarabilmiştir. 1950’lerin bitiminde sona eren film-noir, 1970’lerde neo-noir ve 1980’lerde tech-noir olarak karşımıza çıkar. Bu doğrultuda çalışmada, tech-noirın oluşumunun zemininde yatan unsurlar ve onu besleyen koşullar betimleyici araştırma yöntemi kullanılarak açıklanmaya çalışılmıştır. Bilhassa gelişen teknolojinin insanoğlu üzerindeki olumsuz etkisine odaklanan bu türün; teknofobinin, yabancılaşmanın ve insan soyunun tükeneceğine dair kaygının distopik evrende inşasına yöneldiği tespit edilmiştir.
The concept of authority in the arbitral paradigm
Authors: Bezat Simon
Published: February 2024

International arbitration has been the most misunderstood area of Law since World War II, despite the many 21st century writings attempting to describe it. However, authors usually merely comment on the various articles of a precise arbitration regulation, without really taking the time to question the inner workings of the arbitral paradigm as a whole. And yet, said paradigm is far from anecdotal given how the crushing majority of commercial exchanges and energy-related transactions is ruled by arbitration. This is precisely what this book is aimed at: to understand the arbitral phenomenon in order to then question it and attempt to discover its foundations, mostly through a restored conception of authority, which has been seriously misconstrued for the past centuries and counting.10
Enhancing Operations Quality Improvement through Advanced Data Analytics
Authors: Noman A H M , Mustaquim S M , Molla Selim , Siddique Iqtiar Md
Published: February 2024

This study focuses on the application of data analytics algorithms for real-time monitoring in additive manufacturing processes. The utilization of advanced analytics plays a pivotal role in enhancing the quality control and efficiency of these manufacturing techniques. The research explores how data-driven insights can be harnessed to identify, analyze, and rectify deviations in the manufacturing process, ensuring optimal performance and product quality. By integrating sophisticated monitoring algorithms, the study aims to create a robust framework that continuously analyzes various parameters during additive manufacturing. This includes monitoring factors such as temperature, pressure, and material properties in real-time. The collected data is processed through advanced analytics tools to detect anomalies or deviations from the expected standards. The implementation of machine learning algorithms further facilitates predictive maintenance and proactive adjustments, contributing to the overall reliability and effectiveness of additive manufacturing processes. The outcomes of this research hold significant implications for industries relying on additive manufacturing technologies, providing a foundation for improved process control and product quality. The study contributes to the growing field of Industry 4.0 by showcasing the integration of data analytics as a key enabler for efficient and reliable additive manufacturing.
NOVA APLIKACIJA DOSTUPNOSTI PODATAKA NA SCADA SISTEMU U NDC SRBIJE
Authors:   JSC ELEKTROMREZA SERBIA, Veselinović Jelena
Published: February 2024

A new application made upon EMS Serbia’s request, SCADA Data availability (DA), with the goal of providing a better insight of the quality of SCADA data globally in real-time, which also has the possibility of keeping track of the quality parameter SCADA data through historical database. This application performs SCADA data availability calculations on several levels, by different SCADA data categories and with a predefined sequence cycle periodicity. In that way, all SCADA data are being constantly monitored in real-time, therefore enabling a very fast discovery and detection of malfunctions and “BAD/SUSPECT” measurements, locating them and drawing conclusions about possible causes of malfunctions.
ANALIZA UTICAJA VISINE VETROGENERATORA NA NIVO BUKE U OKOLINI VETROELEKTRANE
Authors:   University of Belgrade, School of Electrical Engineering, Bjelić Miloš , Šumarac Pavlović Dragana ,   University of Belgrade, School of Electrical Engineering, Mijić Miomir ,   University of Belgrade, School of Electrical Engineering, Grbić Maja ,   Electrical Engineering Institute "Nikola Tesla",  Belgrade, Serbia, Miljković Tatjana ,   University of Belgrade, School of Electrical Engineering, Stojanović Radomir ,   WINDVISION DEVELOPMENT Belgrade, Serbia
Published: February 2024

When planning the construction of a new wind power plant, it is necessary to analyze its impact on the environment from the aspect of noise. It is necessary to check whether the expected noise levels after the construction of the wind power plant are within the permitted limits, taking also into account the existing noise levels in the environment. The paper analyzes the influence of wind generator height on the noise level that occurs in the vicinity of the wind power plant. The analysis is based on software modeling and the results of the calculation of noise levels in the vicinity of the wind power plant. The calculation was performed for the selected type of wind generator and for two hub heights and a conclusion was given regarding the influence of hub height on the noise levels in the vicinity of wind power plant
Implementasi Multibeam Echosounder sebagai Alat Bantu Pencarian Rambu Penuntun yang Runtuh di Alur Pelayaran Sungai Kapuas Pontianak
Authors: Siregar Nathanael Bagaskara , Danial Mochammad Meddy , Lestari Arfena Deah , Meirany Jasisca , Supriyadi Asep
Published: February 2024

The Pontianak Kapuas River has a narrow shipping lane with a one-way route system. To reduce the danger in sailing in the shipping channel, a navigation tool is needed in the form of cardinal buoy. Based on the information obtained, there is a cardinal buoy 1 that has collapsed and endangered the shipping lanes. So it is necessary to carry out a hydrographic-bathymetric survey using the Multibeam Echosounder (MBES) technology. This survey aims to identify the coordinates and direction of the cardinal buoy object. The sounding method is a method used to obtain water depth data in the survey area. After processing the data, it was found that the coordinates of the cardinal buoy that collapsed were 0°4'29" N - 109°10'02" E and experienced a position shift of around ± 38 meters. The cardinal buoy that have been found do not block the shipping lanes because of their position as far as 240.39 meters from the shipping lanes. For this reason, the cardinal buoy that has collapsed does not need to be lifted, only a marker bouy is given,
PAI Teachers' Efforts in Fostering Blink's Style of Dress in Indonesia
Authors: Nursakti Muhammad Saman , Slamet Ubaidillah Al-Ghifary , Widyastri Sri
Published: February 2024

This study aims to analyze and find out the right efforts for PAI teachers in maintaining the dressing style of students, especially students who idolize the Black Pink band which is usually called Blink. This study used descriptive qualitative method. Using primary sources obtained from interviews with PAI teachers, school documents, and interviews with students who idolize Black Pink. In addition, researchers also get secondary sources that researchers get from the internet, books, and the latest journals. Based on the results of research that has been obtained, it shows that the right PAI teacher's efforts in maintaining Blink's dressing style at SMAN 06 Bekasi are to provide religious advice and advise students to be wise in using social media, provide examples to students, provide punishment if they violate with punishment that does not hurt, collaborate with the entire academic community, and parents. As well as creating a good environment for students, by introducing Islamic heroes and instilling moral values to students.
Literasi Edukasi Aplikasi Keuangan Digital Bukuwarung pada UMKM Warmindo Fortuna dan Warmindo Wisesa
Authors: Lussy Michi , Airawaty Diana
Published: February 2024

Micro, small and medium enterprises (MSMEs) continue to increase because they are the ones that play a greater role in the national economy. There are still many obstacles experienced by MSME actors related to financial management skills which is one of the problems faced. The importance of financial literacy through bookkeeping applications for MSMEs can help MSME actors record financial transactions and make it easier to arrange product sales. This study aims to provide education on the digitization of financial bookkeeping and financial literacy to MSME players Warmindo Fortuna and Warmindo Wisesa with the target that these MSMEs can carry out simple financial bookkeeping. This research was conducted in Depok District, Sleman Regency using qualitative methods. The author collected research data by observation, interviews and documentation. The results of the research show an increase in understanding and knowledge of business actors, it is hoped that this literacy can be felt by MSME business actors.
Mengubah Laut Menjadi Kesempatan: Pengembangan Usaha Keripik Kertas Rumput Laut
Authors: Hidayat Nurul , Amanda Allesandra Dior , Salwa S Agustina Neesha , Azhar A A. Rezki Hidayat Ryan , Felicia Rusdianti Lutfiah Adeline , Dewi S Elyza
Published: February 2024

This community service journal aims to find out how to process seaweed so that it can become a product that has selling value. This research involved an UMKM person who has the ability in the field of seaweed processing. Through a series of training and mentoring, we were taught how to process seaweed into a product that has a selling value, namely “kringkel”. Kringkel is a product whose main raw material is seaweed. Other raw materials used in this product are glutinous rice flour, cheese, vanilla, sugar, salt, milk, and eggs. Kringkel has a crunchy texture and has a savory and salty taste from the cheese. Kringkel is also included in the typical souvenirs of Tarakan. In making kringkel, there are influencing factors such as the quality of seaweed used, the amount of ingredients, the frying temperature, the right way to fry when the dough has been put into the pan, and how to package. The result of this service is that the community can utilize the resources around them to be able to create new business opportunities that are beneficial personally and to the people around them. This not only increases their income, but also encourages economic independence.
The Effect Of Education With The Adolescent Reproductive Health Module On Increasing Peer Counselors' Knowledge About Family Life Planning In Pelamunan Village
Authors: Nurfazriah Indah , Nurhayati Annisa , Irianti Susi , Suriani Sari , Mathofani Puji Eka
Published: February 2024

Early marriages in Indonesia result in various detrimental impacts, encompassing psychological, social, and health aspects. Psychologically, teenagers marrying early often struggle to navigate their emotional well-being amidst household challenges, contributing to an escalating divorce rate within this demographic. Additionally, early marriage poses significant risks to reproductive health, particularly for teenage girls, leading to complications such as premature birth, bleeding, and low birth weight (LBW) babies. Consequently, this trend contributes to the rising maternal and infant mortality rates. To address these issues, an analysis is conducted to understand the impact of providing education through e-modules on enhancing teenagers' knowledge concerning family planning preparation. The research employs a Quasi Experiment pre-test post-test design with a control group. The study focuses on peer counselors within the Kramatwatu Family Planning Hall work area, totaling 17 students, utilizing total sampling as the sampling technique. Findings reveal a notable improvement in peer counselors' average knowledge, increasing from 61.47 before education to 75.59 afterward, indicating a difference of 14.09. Statistical tests using the T-Test result in a significant p-value of 0.000 ? 0.05, leading to the acceptance of Ha or rejection of Ho. Hence, it can be concluded that there is a substantial increase in knowledge among peer counselors in the control group regarding Family Life Planning. Future research endeavors should explore the development of peer counseling modules covering diverse topics beyond family planning to comprehensively address the needs of adolescents.
Prediction Of Cryptocurrency Prices Using Lstm, Svm And Polynomial Regression
Authors: Al Giffary Novan Fauzi , Sulianta Feri
Published: February 2024

The rapid development of information technology, especially the Internet, has facilitated users with a quick and easy way to seek information. With these convenience offered by internet services, many individuals who initially invested in gold and precious metals are now shifting into digital investments in form of cryptocurrencies. However, investments in crypto coins are filled with uncertainties and fluctuation in daily basis. This risk posed as significant challenges for coin investors that could result in substantial investment losses. The uncertainty of the value of these crypto coins is a critical issue in the field of coin investment. Forecasting, is one of the methods used to predict the future value of these crypto coins. By utilizing the models of Long Short Term Memory, Support Vector Machine, and Polynomial Regression algorithm for forecasting, a performance comparison is conducted to determine which algorithm model is most suitable for predicting crypto currency prices. The mean square error is employed as a benchmark for the comparison. By applying those three constructed algorithm models, the Support Vector Machine uses a linear kernel to produce the smallest mean square error compared to the Long Short Term Memory and Polynomial Regression algorithm models, with a mean square error value of 0.02.
LIVING HADIS DALAM TRADISI NGUPATI DI DESA TALAGASARI KECAMATAN CIKUPA KABUPATEN TANGERANG PERSPEKTIF PSIKOLOGI SOSIAL
Authors: Abdullah Abdullah , Haris Haris , Nurfatsyah Zein Khumaedi
Published: February 2024

Penelitian ini membahas tentang hadis tradisi ngupati di Desa Talagasari Kec. Cikupa Kab. Tangerang, tradisi sangatlah penting yaitu melestarikan suatu adat, salah satunya adalah upacara ngupati, dimana tradisi ini dilakukan sebagai bentuk rasa syukur atas karunia yang telah diberikan oleh Allah. Tradisi ngupati yang dipraktikkan oleh sebagian masyarakat desa Talagasari Kec. Cikupa Kab. Tangerang merupakan salah satu upaya untuk mensyukuri janin yang dikandungnya saat usia kandungan mencapai empat bulan. Rumusan masalah yang ditemukan oleh penulis akan dibahas melalui penelitian yakni Bagaimana living hadis dalam tradisi ngupati di Desa Talagasari Kec. Cikupa Kab. Tangerang? Penelitian ini menggunakan metode kualitatif deskriptif dengan pendekatan living hadis. Teknik pengumpulan data dilakukan melalui observasi, wawancara serta dokumentasi, adapun dalam menganalisis data yang dilakukan dalam skripsi ini adalah analisis deskriptif dengan menggunakan teori living hadis, fenomenologi dan psikologi. Hasil dari penelitian ini adalah Kegiatan tradisi ngupati di Desa Talagasari Kecamatan Cikupa Kabupaten Tangerang yaitu bukan kegiatan biasa akan tetapi kegiatan yang berlandasan dengan hadis Nabi Saw, secara turun temurun yang dilakukan oleh para leluhur terdahulu yang berkembang hingga saaat ini, dengan adanya tradisi ngupati masyarakat dapat lebih bersyukur kepada Allah Swt yang telah mengutus malaikat meniupkan ruh untuk sang janin yang berada didalam kandungan seorang ibu dalam usia empat bulan, supaya sang janin dan ibunya sehat dan dimudahkan dalam proses melahirkan nanti
Afet Yönetim Döngüsü Çerçevesinde Kamusal Alanların Önemi: 6 Şubat Kahramanmaraş Depremi Deneyimi
Authors: Turna Başak , Savaş Yavuzçehre Ponar
Published: February 2024

Türkiye, coğrafi konumu ve jeolojik yapısı nedeniyle çeşitli afetlere maruz kalan bir ülkedir. İnsanların olağan yaşamsal faaliyetlerini kesintiye uğratan afetler, fiziksel, ekonomik ve sosyal alanlarda olmak üzere pek çok alanda olumsuz sonuçlara yol açmaktadır. Bu bakımdan, olası can ve mal kayıplarını önlemek adına afet yönetimi ile ilgili gerekli önlemlerin alınması hayati önem taşımaktadır. Bu kapsamda çalışma, kamusal alanların önemine ve afet anlarında üstlenebileceği işlevlere dikkat çekmeyi amaçlamaktadır. Çalışmada, 6 Şubat 2023 tarihinde Türkiye'nin Kahramanmaraş ilinde meydana gelen depremler sonrasında büyük hasar gören Dulkadiroğlu İlçesi örnek alan olarak seçilmiş ve sorgulayıcı ve yorumlayıcı bir kaygı ile nitel araştırma yöntemleri (yerinde gözlem, doküman analizi) kullanılmıştır. Dulkadiroğlu İlçesi ile sınırlı olan bu çalışmada, yerel yönetimlerin stratejik planlarında ve uygulamalarında kriz anlarına yönelik sakınım politikalarının bulunmadığı, kamusal alanların afet sonrasına yönelik yeterli tasarıma sahip olmadığı bulgusuna ulaşılmıştır.
The Influence of Overconfidence Bias, Herding Effect, and Loss Aversion on Investment Decisions in The Capital Market with Financial Literacy as A Moderating Variable
Authors: Firmansyah Firmansyah
Published: February 2024

This study aims to examine the effect of overconfidence bias, herding effect, and loss aversion on investment decisions in the capital market with financial literacy as a moderating variable study on Generation Z novice investors in Malang. Sample determination is used by the accidental sampling method. The research data sources came from observations, interviews and questionnaires. Data analysis using the SEM-PLS approach with WarpPLS 7.0 software. The results showed that overconfidence bias, herding effect, and loss aversion had a positive and significant effect on investment decisions. Financial literacy can moderate the effect of overconfidence bias, and loss aversion on investment decisions. Financial literacy cannot moderate the influence of the herding effect on investment decisions.
The Impact of Brand Awareness, and Product Attributes to Increase Purchase Intention (Study Case: Transvision)
Authors:   School of Business Management, Institute Technology of Bandung, Indonesia, Dewi Fianti Krisna , Belgiawan Prawira Fajarindra ,   School of Business Management, Institute Technology of Bandung, Indonesia
Published: February 2024

In the dynamic landscape of the Indonesian television industry, the rise of over-the-top (OTT) services poses a major challenge to traditional pay-TV providers such as Transvision. Intense competition from emerging OTT providers in Indonesia requires innovative strategies to secure customer acquisition. Indonesia is one of the fastest growing pay-TV markets, with a predicted CAGR of 5% and revenue projections of $633 million by 2025. The demographic differences between OTT and pay TV users, highlight the need for a customized marketing approach. In detail, Transvision, which offers pay TV services through Android TV box devices, faces hurdles in terms of market penetration and brand recognition. This study aims to propose an effective transvision marketing strategy while considering the complex dynamics of the evolving television landscape in Indonesia. Using a quantitative approach, the research conducted an examination of customers and hypothesis testing, administering surveys to android TV box users in the Jabodetabek area. The data, processed through SEM-PLS, indicated that social media marketing and electronic word of mouth positively impact brand awareness. Furthermore, significant product attributes, including variety of content and additional features, subscription package price, and payment method options, were found to influence purchase intention. The study concludes that both brand awareness and product attributes play pivotal roles in shaping purchase intention.
Direct compression of diclofenac sodium tablet using modified Musa paradisiaca pseudostem cellulose-corn starch polymer alloy
Authors:   Department of Pharmaceutics and Pharmaceutical Technology, Dora Akunyili College of Pharmacy, Igbinedion University, Okada, Edo State, Nigeria, Nnamani Nnabuike , Adedokun Oluwasegun ,   Department of Pharmacognosy and Natural Products, Afe Babalola University, Nigeria, Esezobo Samson ,   Department of Pharmaceutics and Pharmaceutical Technology, Dora Akunyili College of Pharmacy, Igbinedion University, Okada, Edo State, Nigeria, Onaga Ignatius ,   Department of Pharmaceutics and Pharmaceutical Technology, Dora Akunyili College of Pharmacy, Igbinedion University, Okada, Edo State, Nigeria
Published: February 2024

Background: Biomaterials exhibit different functional properties. The aim of this study is to formulate direct compressible diclofenac sodium tablet using modified pseudostem cellulose and starch complex. Methods: Cellulose was extracted from Musa paradisiaca pseudostem and modified using acid-hydrolysis and fermentation techniques. The modified cellulose was evaluated using FT-IR analysis. Avicel pH-101 was used as control cellulose. Micromeritic properties of the modified cellulose were evaluated using tapped consolidation technique. Co-milling heat technique was used to produce polymer-alloy of 21.7, 43.4 or 87.0% of modified cellulose and 78.3, 56.6, or 13.0% dried corn starch respectively. The dried starch or polymer-alloy was blended with diclofenac sodium, co-povidone and magnesium stearate to produce batches A - G. The blends were analyzed for Kawakita densification properties before being compressed to tablets. The physicochemical and drug-release properties of the tablets were evaluated. Results: Of the dried pseudostem mass, 52.01% and 48.04% of extracted and modified celluloses respectively were obtained. The FTIR study showed presence of cellulose in the pseudostem extract and no interaction between the cellulose and diclofenac sodium. The celluloses had Hausner’s ratios < 1.32 and Carr’s indices < 23.54%. The polymer-alloy blends showed Kawakita compressibility < 16.34 and compactibility > 489.30. The control tablets passed physicochemical properties tests. The test tablets had hardness > 12.34 KgF, disintegration time > 144.67 min, and released 7.64 - 77.59% drug in acidic to basic medium over 240 min. The result indicates that the pseudostem-cellulose was flow-able, and produced compactible polymer alloys and extended drug-release tablets. Conclusion: Direct compression of diclofenac sodium with Musa paradisiaca pseudostem cellulose-corn starch polymer-alloy produced compact tablets with extended drug release. Keywords: Acid-hydrolysis, co-milling, compressibility, drug release
Molecular docking assessment of the tocolytic potential of phytoconstituents of five medicinal plants used against preterm labour
Authors:   Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Benin, PMB 1154, Benin City, 300001, Nigeria, Ogbeide Uyi , Oriotor Eunice , Okeri Henry
Published: February 2024

Introduction: Preterm labour is currently being treated with a number of medications with untoward side effects, but many medicinal plants have also been found useful. This study aims to assess the tocolytic potentials of the phytoconstituents of Barteria fistulosa, Ficus capensis, Ficus exasperate, Newbouldia laevis and Zingiber officinale. Methods: Phytoconstituents present in these plants were obtained from literature sources, their 3D SDF structures were obtained from PubChem; the protein Beta-2 adrenergic receptor (7DHI) was processed using Chimera and molecular docking was done using PyRx software. Post-docking analysis was done using Bio-discovery Studio 2.0 and ADMET profiling was done using the Swiss ADME web server and ProTox-II virtual lab. Results: A binding affinity value of less than -7 kcal/mol was found for nine (9) phytoconstituents in Zingiber officinale, fourteen (14) phytoconstituents in Ficus capensis, three (3) phytoconstituents in Ficus exasperata, one (1) phytoconstituent in Barteria fistulosa and forty-four (44) phytoconstituents in Newbouldia laevis. Following post-docking analysis and ADMET profiling of specific ligands from the plants, Kaempferol, Chrysoeriol and Lapachol - all present in Newbouldia laevis - were identified as putative drug molecules based on their higher binding affinity and hydrogen bond interaction with the target proteins' active site amino acid residues. Conclusion: The tocolytic potential of Zingiber officinale, Ficus capensis, Barteria fistulosa and Newbouldia laevis as a medicinal plant for the treatment of preterm labour is validated. Kaempferol, Chrysoeriol and Lapachol, phytoconstituents in Newbouldia laevis possess the potential as a source of new drugs for the treatment of preterm labour. Keywords: Preterm labour, tocolysis, molecular docking, drug design
Characterization of Avocado (Persea americana) Seed Starch - Physicochemical and Powder Properties
Authors:   Department of Pharmaceutics and Pharmaceutical Technology, College of Pharmacy, Igbinedion University, Okada, Edo  State, Nigeria, Enadeghe Osaretin D , Eraga Sylvester O ,   Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, University of Benin,  PMB 1154, Benin City, 300001, Nigeria, Obarisiagbon Johnbull A ,   Department of Pharmaceutics and Pharmaceutical Technology, College of Pharmacy, Igbinedion University, Okada, Edo  State, Nigeria
Published: February 2024

Introduction: Starch is a biopolymer commonly used as an excipient in pharmaceutical formulations due to its biocompatibility, inertness, biodegradability, availability and affordability. Purpose: The study aimed to extract and characterize the starch isolated from avocado (Persea americana) seeds and investigate its disintegrant and binder properties in paracetamol tablet formulations. Methods: Starch was extracted from avocado seed using standard methods and then subjected to some phytochemical, physicochemical and bulk powder properties analyses. High-resolution analyses using differential scanning calorimetry (DSC), Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM) and x-ray diffractometry (XRD) were also carried out on the extracted starch powder. Results: Starch extraction yield was 19.61% and the starch was light-brown in colour, odourless, tasteless and smooth in texture. The starch showed a melting point range of 102-114°C and moisture content of 22.7%. It also exhibited a hydration capacity of 2.76 g/g and swelling and moisture sorption capacities of 46.43 and 115.34%, respectively. The starch powder was cohesive with poor flow properties but the DSC, FTIR, SEM and XRD results showed a semi-crystalline powder composed of fluffy discrete particles. Conclusion: The starch isolated from P. americana seeds exhibited good swelling, hydration and moisture sorption capacities, making it a good candidate as a tablet disintegrant. Keywords: Avocado, starch, physicochemical, high-resolution, analyses
Az intellektuális tőke mérési lehetőségei egy vállalati példán keresztül
Authors: Váradi Lucia , Hamad Mirjam
Published: February 2024

Our research aims to examine the “invisible value” found at UPC Magyarország Kft. Since Vodafone Magyarország Nyrt. announced the acquisition of UPC Magyarország Kft. in 2020. Our research is aimed at using different methods to determine the invisible assets, intellectual capital, and added value, which cannot be determined directly from the financial statements of UPC Magyarország Kft. Since the financial statements prepared based on accounting principles follow the principle of prudence, many assets (mainly intangible assets) are not shown in the financial statements, so they only become visible after the moment of acquisition. Three different methods were used to measure intellectual capital, then the results were compared. The three methods use different points of view to measure intellectual capital and approach the concept of intellectual capital from other points of view. The CIV method shows us the lack of intellectual capital in relation to the industry or the surplus value; The EVA indicator explicitly shows us the intellectual capital size; and the VAIC method the efficiency of intellectual capital.
CURRÍCULOS CRÍTICOS INTERCULTURALES PARA UNA EDUCACIÓN CONTEXTUALIZADA: REVISIÓN SISTEMÁTICA DE LA LITERATURA
Authors: Blanchar Añez Francisco Javier
Published: February 2024

Los sistemas educativos, además de atender las necesidades en temas de cobertura, calidad y permanencia, se enfrentan a la persistencia histórica de brechas de aprendizaje y desarrollo entre las diversas comunidades. Fenómenos como las migraciones y dinámicas cambiantes de orden social y económico han generado una serie de limitaciones territoriales, de género, acceso a derechos y capacidades de formación. Estas necesidades podrían ser atendidas desde la escuela, si se da la participación de los actores educativos con propuestas curriculares pertinentes. La presente investigación tiene como objetivo analizar las potencialidades, capacidades y problemáticas sociales, culturales y ambientales de una comunidad rural, para construir participativamente una propuesta educativa, en el marco de un currículo intercultural para la formación de los estudiantes en turismo en un corregimiento del Distrito Turístico y Cultural de Riohacha, Colombia. La ponencia presenta los resultados del proceso de revisión sistemática de la literatura científica a través de la metodología PRISMA 2020, con la revisión de 48 referencias documentales de tres fuentes (bases de datos; registros, revistas y repositorios y fuentes alternativas). Los resultados indican que la escuela y sus currículos responden a diversas perspectivas: como sistema estandarizador y homogeneizante desde la perspectiva tradicional, especialmente en naciones europeas; como ente que reconoce oficialmente la diversidad cultural que convergen en el aula (multiculturalismo), sin una atención real y práctica a estas; y, como un dispositivo de poder, empoderamiento y disputa, para reconocer y posibilitar la participación de comunidades vulneradas históricamente frente a problemáticas de índole económico, social, cultural.
L’ancrage idéologique du Séminaire vaudois de culture théologique
Authors: Bastian Jean-Pierre
Published: February 2024

Afin de préciser l’héritage théologique dans lequel le Séminaire de culture théologique s’est inscrit par ses fondateurs, il convient d’explorer la manière dont les libristes ont développé leur enseignement théologique au fil du temps au sein de leur Faculté fondée à Lausanne en 1847. Il nourrit la formation octroyée aux laïcs mettant en œuvre une pédagogie de la conviction ancrée dans la théologie du Réveil propagée durant plus d’un siècle (1847-1966) par l’Église évangélique libre du canton de Vaud et par sa Faculté. Au lendemain de la Seconde Guerre mondiale, il s’agissait plus largement de repenser l’implication du christianisme dans la société. Le Séminaire contribua ainsi à renforcer la place des laïcs et à démocratiser l’accès à la théologie.
Skrining Kesehatan Upaya Deteksi Dini Penyakit tidak Menular pada Lansia Kalurahan Wonolelo, Bantul
Authors: Tursilowati Sri Yuni , Viantika Kusumasari Raden Roro , Isnaini Yeni
Published: February 2024

Berdasarkan hasil pengumpulan data ditemukan bahwa PTM merupakan penyakit tertinggi yang ada di masyarakat diantaranya hipertensi. Pengabdian kepada Masyarakat dilaksanakan untuk deteksi dini PTM lansia di Kalurahan Wonolelo Kabupaten Bantul sebagai upaya pencegahan PTM. Sasaran dan lokasi: Lansia di Kalurahan Wonolelo Kabupaten Bantul yang berjumlah 74 orang. Metode yang digunakan yaitu melakukan edukasi kesehatan dengan tehnik konseling dan pemeriksaan kesehatan pada lansia berupa cek tekanan darah, kadar glukosa darah, dan pengukuran status gizi. Alat yang digunakan tensimeter, alat cek glukosa darah portabel, timbangan injak, dan statu meter. Hasil skrining PTM hipertensi dari 74 lansia yang hipertensi sebanyak 38 lansia (51,4 %) dan yang normal 36 lansia (48,6%),yang gula darah tinggi 7 lansia (9%) dan yang normal 93 lansia (91%), sedangkan hasil IMT lansia yang berisiko PTM 28 lansia (37,8%) dan yang tidak berisiko 46 lansia (62,2 %) . Sehingga perlu edukasi upaya pencegahan PTM. Hasil edukasi upaya pencegahan penyakit hipertensi dan diabetes pengetahuan sebelum edukasi memiliki rata-rata 40 dan terjadi peningkatan nilai 100% lansia yang mengikuti kegiatan abdimas berupa skrining cek gula darah dan tekanan darah tinggi serta edukasi pencegahan PTM pengetahuan menjadi rata-rata 95. Lansia jadi mengetahui upaya pencegahan PTM.