bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengembangan Media Pembelajaran Agama Islam Berbasis Kecerdasan Buatan: Perspektif Pendidikan Agama Islam
Authors: Hafiz Abdul , Mu’ti Abdul , Amirrachman Alpha
Published: January 2025

Pengembangan media pembelajaran yang inovatif menjadi penting dalam meningkatkan kualitas pendidikan agama Islam di era digital. Penelitian ini bertujuan untuk mengkaji dan mengembangkan media pembelajaran berbasis kecerdasan buatan (AI) dalam konteks pendidikan agama Islam. Penggunaan AI dalam pendidikan agama Islam menawarkan berbagai keunggulan, termasuk personalisasi pembelajaran, peningkatan interaksi siswa-guru, dan aksesibilitas materi pembelajaran yang lebih luas. Metode penelitian yang digunakan adalah pendekatan kualitatif dengan teknik analisis deskriptif. Data dikumpulkan melalui wawancara dengan ahli pendidikan Islam, praktisi teknologi pendidikan, serta pengamatan langsung terhadap implementasi media pembelajaran berbasis AI. Hasil penelitian menunjukkan bahwa media pembelajaran berbasis AI dapat meningkatkan pemahaman siswa terhadap materi ajar, memfasilitasi pengajaran yang lebih interaktif, dan memberikan umpan balik yang lebih efektif kepada siswa. Selain itu, integrasi AI dalam pembelajaran agama Islam juga menghadirkan tantangan seperti kebutuhan akan infrastruktur teknologi yang memadai dan pelatihan guru dalam penggunaan teknologi tersebut. Penelitian ini menyimpulkan bahwa pengembangan media pembelajaran berbasis AI merupakan langkah strategis dalam meningkatkan kualitas pendidikan agama Islam, dengan syarat adanya dukungan yang komprehensif dari berbagai pihak terkait.
The development of innovative learning media is important in improving the quality of Islamic religious education in the digital era. This research aims to examine and develop artificial intelligence (AI)-based learning media in the context of Islamic religious education. The use of AI in Islamic religious education offers various advantages, including personalization of learning, increased student-teacher interaction, and wider accessibility of learning materials. The research method used is a qualitative approach with descriptive analysis techniques. Data were collected through interviews with Islamic education experts, educational technology practitioners, and direct observation of the implementation of AI-based learning media. The results showed that AI-based learning media can improve students' understanding of teaching materials, facilitate more interactive teaching, and provide more effective feedback to students. In addition, the integration of AI in Islamic learning also presents challenges such as the need for adequate technological infrastructure and teacher training in the use of the technology. This study concludes that the development of AI-based learning media is a strategic step in improving the quality of Islamic religious education, provided there is comprehensive support from various related parties.
Prinsip-Prinsip Dasar Ekonomi Islam
Authors: Rafifah Abu Rahmah , Rahmaniar  , Ambo Masse Rahman
Published: January 2025

Penelitian ini bertujuan untuk menganalisis peran prinsip ekonomi Islam dalam menciptakan kesejahteraan yang berkeadilan bagi seluruh lapisan masyarakat. Dengan menggunakan metode kajian pustaka deskriptif, penelitian ini mengidentifikasi prinsip-prinsip utama ekonomi Islam, seperti keadilan, keseimbangan, tanggung jawab sosial, dan distribusi kekayaan yang adil. Hasil penelitian menunjukkan bahwa ekonomi Islam menawarkan solusi atas berbagai tantangan ekonomi modern, seperti ketimpangan, eksploitasi, dan ketidakadilan, melalui pendekatan yang lebih etis dan berlandaskan nilai-nilai spiritual. Dukungan kebijakan, peningkatan literasi, dan inovasi dalam sistem ekonomi Islam diperlukan agar potensi ini dapat dioptimalkan untuk menciptakan kesejahteraan yang inklusif dan berkelanjutan.
This research aims to analyze the role of Islamic economic principles in creating equitable prosperity for all levels of society. Using a descriptive literature review method, this research identifies the main principles of Islamic economics, such as justice, balance, social responsibility and fair distribution of wealth. The research results show that Islamic economics offers solutions to various modern economic challenges, such as inequality, exploitation and injustice, through a more ethical approach and based on spiritual values. Policy support, increased literacy and innovation in the Islamic economic system are needed so that this potential can be optimized to create inclusive and sustainable prosperity.
Transformation from Neoclassicism to Austrian School: Javier Mileis Economic Evolution
Authors: Moch Enrico
Published: January 2025

Under President Javier Milei, Argentina's economic policies have drastically changed, shifting from neoclassical concepts to an Austrian School-inspired libertarian framework. His administration has placed a high priority on deregulation, fiscal restraint, and monetary stability in an effort to reduce government intervention and combat inflation. The economic, social, and political effects of Milei's actions during his first one-and-a-half years in power are evaluated in this paper, along with views from across the world and the viability of implementing his strategy in Germany. This study uses a mixed-methods approach, using quantitative data (inflation, GDP, unemployment rates, and fiscal balances), secondary literature (economic analysis, political commentary), and primary sources (government programs, Milei's speeches). According to the results, Milei's measures have been effective in lowering inflation, which by October 2024 had dropped from 211% in 2023 to a monthly rate of 2.7%. The social consequences of quick fiscal consolidation are reflected in the fact that these changes have also resulted in an economic recession (GDP -4%), increased unemployment (8%), and a rise in poverty (53%). Reactions to Milei's policies have been divided on a global scale. Keynesian critics warn of economic stagnation and growing inequality, while Austrian and libertarian economists praise his deregulation and fiscal restraint. In terms of transferability, Germany's robust social market economy and institutional protections make full-scale adoption of free-market ideas impossible, even though some of them may be modified there. Future research should look at the long-term impact of Milei's changes and their applicability in various economic circumstances since the study concludes that his initiatives provide both potential and risks and serve as a test case for extreme fiscal conservatism
Peningkatan Kapasitas dan Kualitas Produk serta Implementasi Digital Marketing Sebagai Wujud Inkubator Bisnis Kampung Tudung Desa Grujugan Kebumen
Authors: Blandina Hendrawardani  , Desi Sugiarti  , Ari Sunardi  , Bahtiar Wilantara  , Ari Waluyo  , M. Haikal Ramdani  , Azzahra Kurniafistika  , Candra Ahmad Latief Pratama  , Imam Maulana  , Nasikin  , Tri Wahyuni  , Widya Audy Febriyanti  , Ade Pangestu  , Siti Nurjannah  , Rangga Maulana Insani
Published: January 2025

Kegiatan pemberdayaan masyarakat desa melalui Program Ormawa Membangun Negeri dalam peningkatan kapasitas dan kualitas produksi perajinan anyaman bambu dalam wadah inkubator bisnis yang ada di desa melalui Bumdes membawa pembedayaan yang berdampak dan memberikan output kegiatan yang nyata dalam mengubah cara bekerja pengrajin lebih efektif dan efisien. Metode pembedayaan yang digunakan mencakup pendekatan partisipatif dan kolaboratif dengan masyarakat lokal, organisasi lokal, dan instansi terkait. Hasil dari kegiatan ini adalah produksi pengrajin dari cara yang tradisional beralih menggunakan mesin, kualitas produk unggulan meningkat karena kecepatan produksi serta kualitas produk inovasi yang memiliki nilai jual, dan terwujudnya inkubator bisnis yang ditetapkan melalui Peraturan Desa. Aktifnya media social dan marketplace sebagai sarana pemasaran online yang efektif. Kolaborasi pentahelix dalam pemberdayaan masyarakat ini menjadi kerjasama tim yang solid dan sumber daya manusia terlibat secara aktif sehingga memberikan dampak perubahan bagi pengrajin dan Pemerintah Desa.
KONSEP EKONOMI KERAKYATAN SEBAGAI PENGEMBANGAN KOPERASI SYARIAH DI INDONESIA (TELAAH PEMIKIRAN MUHAMMAD HATTA)
Authors: Arifqi Moh. Musfiq
Published: January 2025

Konsep ekonomi kerakyatan adalah salah satu intrumen sistem perekonomian yang ada di Indonesia. Konsep ini digagas oleh Muhammad Hatta. Lahirnya konsep ini dilatar belakangi adanya keterpurukan perekonomian pada masa itu. Pada masa krisis moneter 1997 di Indonesia telah banyak menyebabkan hancurnya perekonomian. Namun, konsep ekonomi kerakyatan masih mampu berdiri tegak dengan prinsipnya saling gotong-royong dalam membangun perekonomian. Bagitupun dengan konsep koperasi syariah yang saat ini terus mengalami peningkatan dengan mengedepankan konsep kekeluargaan. Pendekatan peneltian library research digunakan untuk mempermudah mendeskripsikan hasil penelitian. Hal ini diperoleh melalui karya-karya orisinal Muhammad Hatta, buku-buku, jurnal, artikel serta dokumen lain yang relevan dengan tema pembahasan. Hasil penelitian ini menunjukkan bahwa konsep ekonomi kerakyatan menurut Muhammad Hatta mampu memberikan solusi dalam pengembangan koperasi syariah di Indonesia. Dengan mengedepankan prinsip tolong menolong (at-ta’awun), masyarakat akan lebih percaya dalam bertransaksi di koperasi syariah. Setidaknya ada tiga komponen dasar ekonomi kerakyatan dalam mengembangkan ekonomi syariah, yaitu, prinsip kebersamaan, kekuasaan milik rakyat serta lebih mementingkan orang banyak.
ANALISIS SISTEM PENGENDALIAN INTERNAL DENGAN MENGGUNAKAN SPIP (Studi Kasus Pada Disdukcapil Kota Magelang
Authors: Prastya Yoshandi Rendra , Sunaningsih Suci Nasehati
Published: January 2025

Penelitian ini berujuan untuk mengetahui bagaimana penerapan lingkungan pengendalian, penilaian risiko, kegiatan pengendalian, informasi dan komunikasi, serta pemantauan pengendalian intern di Dinas Kependudukan dan Pencatatan Sipil Kota Magelang. Penelitian menggunakan jenis penelitian kualitatif dengan menggunakan metode analisis deskriptif. Objek dalam penelitian ini adalah Dinas Kependudukan dan Pencatatan Sipil Kota Magelang. Hasil penelitian menunjukkan bahwa penerapan sistem pengendalian intern pemerintah (SPIP) pada Dinas Kependudukan dan Pencatatan Sipil Kota Magelang telah sesuai dengan unsur – unsur yang ada dalam Sistem Kontrol Internal yang telah ditetapkan oleh pemerintah berdasarkan Peraturan Pemerintah No. 60 tahun 2008. Kelemahan dalam penelitian ini adalah kelemahan dalam sistem komputerisai seperti mekanisme pendataan yang terkadang terkendala sehingga dapat menghambat dalam proses pelayanan kepada masyarakat.
Internal transcribed spacer sequencing to explore the intrinsic composition of fungal communities in fungal esophagitis
Authors: Song Yi-Kang , Zheng Lin , Liu Ai-Xin , Ma Jun-Ji
Published: January 2025

BACKGROUND

Fungal esophagitis (FE) is caused by fungal invasion of the esophageal mucosa. Under endoscopy, the esophageal mucosa shows edema, congestion, erosion, and ulceration, and bleeds easily when touched, and the surface of the mucosa is covered with small white spots like "bean curd residue". Clinical cases showing typical FE under endoscopic imaging but negative esophageal mucosal brush (referred to as suspected FE) have increased the difficulty and challenge of clinical diagnosis and treatment. At present, the esophageal fungal flora of suspected case has not been thoroughly studied.

AIM

To characterize the fungal flora in FE, suspected FE, and the esophageal normal controls (NCs), and to identify marker species to improve detection of FE.

METHODS

This was a case-control study. A total of 19 patients with FE, 16 with suspected FE, and 10 NCs were selected by endoscopy. The esophageal cell brush samples of each group were sequenced by internal transcribed spacer (ITS) 1 and analyzed by bioinformatics.

RESULTS

In FE and suspected FE patients, species richness, species diversity and species evenness, as measured by the Chao1 index, Shannon index and Pielou index, were lower than in the NCs, and the comparison between the FE and NCs was the most significant (P < 0.05). Compared with the NCs, the relative abundance of Candida in FE and suspected FE patients was significantly increased (P < 0.001), while the relative abundance of Yarrowia was significantly decreased (P < 0.05). Moreover, Yarrowia abundance in the FE group was significantly lower than in the NCs and suspected FE groups (P < 0.001). The area under the curve for Candida in FE and suspected FE patients was 99.5% (P < 0.05) and 81.3% (P < 0.05), respectively. Finally, compared with FE patients, the relative abundance of Ascomycota and Candida in the esophageal flora of suspected FE patients was decreased, while the relative abundance of Yarrowia , Thermomyces and Pichia was increased.

CONCLUSION

ITS showed that composition of the fungal community was similar in the FE and suspected FE groups. ITS can be used as an auxiliary diagnostic method for FE and provide a theoretical basis for follow-up diagnosis and treatment.
New classification of gastric polyps: An in-depth analysis and critical evaluation
Authors: Liao Xiao-Hui , Sun Ying-Ming , Chen Hong-Bin
Published: January 2025

With the widespread use of upper gastrointestinal endoscopy, more and more gastric polyps (GPs) are being detected. Traditional management strategies often rely on histopathologic examination, which can be time-consuming and may not guide immediate clinical decisions. This paper aims to introduce a novel classification system for GPs based on their potential risk of malignant transformation, categorizing them as "good", "bad", and "ugly". A review of the literature and clinical case analysis were conducted to explore the clinical implications, management strategies, and the system's application in endoscopic practice. Good polyps, mainly including fundic gland polyps and inflammatory fibrous polyps, have a low risk of malignancy and typically require minimal or no intervention. Bad polyps, mainly including hyperplastic polyps and adenomas, pose an intermediate risk of malignancy, necessitating closer monitoring or removal. Ugly polyps, mainly including type 3 neuroendocrine tumors and early gastric cancer, indicate a high potential for malignancy and require urgent and comprehensive treatment. The new classification system provides a simplified and practical framework for diagnosing and managing GPs, improving diagnostic accuracy, guiding individualized treatment, and promoting advancements in endoscopic techniques. Despite some challenges, such as the risk of misclassification due to similar endoscopic appearances, this system is essential for the standardized management of GPs. It also lays the foundation for future research into biomarkers and the development of personalized medicine.
Evaluating the scope of human leukocyte antigen polymorphisms influencing hepatitis B virus-related liver cancer and cirrhosis through multi-clustering analysis
Authors: Li Shi , Xi Yue , Dong Xue-Ying , Yuan Wen-Bin , Tang Jing-Feng , Zhou Ce-Fan
Published: January 2025

Hepatitis B virus remains a major cause of cirrhosis and hepatocellular carcinoma, with genetic polymorphisms and mutations influencing immune responses and disease progression. Nguyen et al present novel findings on specific human leukocyte antigen (HLA) alleles, including rs2856718 of HLA-DQ and rs3077 and rs9277535 of HLA-DP, which may predispose individuals to cirrhosis and liver cancer, based on multi-clustering analysis. Here, we discuss the feasibility of this approach and identify key areas for further investigation, aiming to offer insights for advancing clinical practice and research in liver disease and related cancers.
Mechanistic link between long noncoding RNA and stability of oncogene reveals stemness and chemoresistance of hepatocellular carcinoma
Authors: Liang Yu-Bo , Chen Xing-Ming , Luo Wan-Ling , Ke Yang
Published: January 2025

This letter comments on the recently published manuscript by Yu et al , in which the authors revealed a novel mechanism by which the m6A-modified long noncoding RNA kinesin family member 9-antisense RNA 1 promotes stemness and sorafenib resistance of hepatocellular carcinoma (HCC) through ubiquitin-specific peptidase 1-mediated deubiquitination of oncogene short stature homeobox 2. Given the high mortality rate and poor prognosis of HCC, the findings by Yu et al open a new avenue for overcoming HCC burden by focusing on kinesin family member 9-antisense RNA 1 and short stature homeobox 2 as prognostic markers and therapeutic targets.
Mesalazine alleviated the symptoms of spontaneous colitis in interleukin-10 knockout mice by regulating the STAT3/NF-κB signaling pathway
Authors: Chen Qian , Zhang Ya-Li , Shi Yong-Quan , Zheng Lie
Published: January 2025

BACKGROUND

Excessive endoplasmic reticulum (ER) stress in intestinal epithelial cells can lead to damage to the intestinal mucosal barrier, activate the signal transducer and activator of transcription 3 (STAT3)/nuclear factor kappa B (NF-κB) signaling pathway, and exacerbate the inflammatory response, thus participating in the pathogenesis of ulcerative colitis (UC). Mesalazine is a commonly used drug in the clinical treatment of UC. However, further studies are needed to determine whether mesalazine regulates the ER stress of intestinal epithelial cells, down-regulates the STAT3/NF-κB pathway to play a role in the treatment of UC.

AIM

To study the therapeutic effects of mesalazine on spontaneous colitis in interleukin-10 (IL-10)-/- mice.

METHODS

The 24-week-old IL-10-/- mice with spontaneous colitis were divided into the model group and the 5-amino salicylic acid group. Littermates of wild-type mice of the same age group served as the control. There were eight mice in each group, four males and four females. The severity of symptoms of spontaneous colitis in IL-10-/- mice was assessed using disease activity index scores. On day 15, the mice were sacrificed. The colon length was measured, and the histopathological changes and ultrastructure of colonic epithelial cells were detected. The protein expressions of STAT3, p-STAT3, NF-κB, IκB, p-IκB, and glucose-regulated protein 78 were identified using Western blotting. The STAT3 and NF-κB mRNA expressions were identified using real-time polymerase chain reaction. The glucose-regulated protein 78 and C/EBP homologous protein expressions in colon sections were detected using immunofluorescence.

RESULTS

Mesalazine reduced the symptoms of spontaneous colitis in IL-10 knockout mice and the histopathological damage of colonic tissues, and alleviated the ER stress in epithelial cells of colitis mice. Western blotting and quantitative real-time polymerase chain reaction results showed that the STAT3/NF-κB pathway in the colon tissue of model mice was activated, suggesting that this pathway was involved in the pathogenesis of UC and might become a potential therapeutic target. Mesalazine could down-regulate the protein expressions of p-STAT3, NF-κB and p-IκB, and down-regulate the mRNA expression of STAT3 and NF-κB.

CONCLUSION

Mesalazine may play a protective role in UC by reducing ER stress by regulating the STAT3/NF-κB signaling pathway.
Inhibition of metabotropic glutamate receptor-5 alleviates hepatic steatosis by enhancing autophagy via activation of the AMPK signaling pathway
Authors: Tao Min , Zhang Li-Li , Zhou Guang-Hong , Wang Cong , Luo Xie
Published: January 2025

BACKGROUND

The global prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) has continued to increase annually. Recent studies have indicated that inhibition of metabotropic glutamate receptor 5 (mGluR5) may alleviate hepatic steatosis. However, the precise mechanism warrants further exploration.

AIM

To investigate the potential mechanism by which mGluR5 attenuates hepatocyte steatosis in vitro and in vivo .

METHODS

Free fatty acids (FFAs)-stimulated HepG2 cells were treated with the mGluR5 antagonist MPEP and the mGluR5 agonist CHPG. Oil Red O staining and a triglyceride assay kit were used to evaluate lipid content. Western blot analysis was conducted to detect the expression of the autophagy-associated proteins p62 and LC3-II, as well as the expression of the key signaling molecules AMPK and ULK1, in the treated cells. To further elucidate the contributions of autophagy and AMPK, we used chloroquine (CQ) to inhibit autophagy and compound C (CC) to inhibit AMPK activity. In parallel, wild-type mice and mGluR5 knockout (KO) mice fed a normal chow diet or a high-fat diet (HFD) were used to evaluate the effect of mGluR5 inhibition in vivo .

RESULTS

mGluR5 inhibition by MPEP attenuated hepatocellular steatosis and increased LC3-II and p62 protein expression. The autophagy inhibitor CQ reversed the effects of MPEP. In addition, MPEP promoted AMPK and ULK1 expression in HepG2 cells exposed to FFAs. MPEP treatment led to the nuclear translocation of transcription factor EB, which is known to promote p62 expression. This effect was negated by the AMPK inhibitor CC. mGluR5 KO mice presented reduced body weight, improved glucose tolerance and reduced hyperlipidemia when fed a HFD. Additionally, the livers of HFD-fed mGluR5 KO mice presented increases in LC3-II and p62.

CONCLUSION

Our results suggest that mGluR5 inhibition promoted autophagy and reduced hepatocyte steatosis through activation of the AMPK signaling pathway. These findings reveal a new functional mechanism of mGluR5 as a target in the treatment of MASLD.
Analysis of the effectiveness of acne drug therapy
Authors: Melnikova Yu. E. , Trapchevskaya E. K.
Published: January 2025

Relevance. Acne is one of the most common dermatological diseases, affecting a significant proportion of the population, particularly adolescents and young adults. The modern pharmaceutical market offers several drugs for acne treatment, including topical retinoids, antibiotics, benzoyl peroxide, and azelaic acid, as well as systemic drugs, such as isotretinoin and hormonal agents. The growing problem of antibiotic resistance among microorganisms, including Propionibacterium acnes, requires rational antibacterial drug use and alternative acne treatment methods.

Objective. A comprehensive analysis of the effectiveness of various methods of acne drug therapy to optimize treatment approaches and improve therapy results.

Methods. As part of this review study, a comprehensive analysis of the scientific literature on acne drug therapy was conducted. The inclusion criteria were original studies, meta-analyses, and systematic reviews published over the past 5 years (2018–2023).

Results. An analysis of the literature has shown that topical retinoids and antibiotics, as well as systemic retinoids and antibiotics, remain the most effective methods of treating acne.

Conclusion. The analysis of the modern scientific literature confirms the effectiveness of existing methods of drug therapy for acne. The choice of optimal therapy should be based on the individual characteristics of the patient, the severity of the disease and the presence of concomitant factors.
Potential role of PAR2 inhibitors for treating rheumatoid arthritis
Authors: Fedorov V. N. , Korsakov M. K. , Khokhlov A. L. , Arshinov A. V. , Vdovichenko V. P. , Leonova O. V. , Suleymanov S. Sh.
Published: January 2025

Rheumatoid arthritis (RA) is a multifactorial incurable immune-inflammatory disease. Progression leads to joint deformation, cartilage and bone tissue destruction, and subsequent disability. The primary goal of RA pharmacotherapy is to achieve disease remission. For this purpose, several classes of drugs are used: basic anti-inflammatory drugs (DMARDs), which are a large group of synthetic and biological drugs that are combined according to their ability to influence the pathogenetic mechanisms of RA; glucocorticoids, which are recommended for use in combination with DMARDs; and non-steroidal anti-inflammatory drugs, which are used to relieve acute and chronic pain. The treatment of RA is a long-term process, and the drugs used for this condition are not always safe and not always effective, which leads to discontinuation of treatment in 20–50 % of patients. Therefore, there is a need to develop new pharmacological targets that can increase drug effectiveness and reduce drug toxicity. One promising therapeutic target is proteinase-activated receptors (PARs), particularly PAR2, whose activation contributes to the occurrence of inflammation, fibrosis, and proliferation of connective tissue. Experiments have demonstrated that inhibition of PAR2 activity prevents the development of RA pathogenesis and positively modifies the course of the disease. The search for drugs that inhibit PAR2 was carried out in the following directions: indirect blockade of PAR2 activity; creation of monoclonal antibodies; search for PAR2 inhibitors among peptide compounds; synthesis of low-molecular-weight inhibitory substances.
Automation testing to improve the quality of medical applications
Authors:   Senior QA Engineer, Publicis Sapient Arlington, VA , USA, Ismagambetov Zhenis
Published: January 2025

This article identifies the primary advantages of automating the testing processes of medical applications, significantly enhancing their reliability and safety. Special attention is given to methodologies such as Total Quality Management and Plan-Do-Check-Act, as well as the application of mobile technologies in healthcare, which contribute to error minimization and improved treatment quality. The article describes a multi-stage study, including an analysis of scientific publications, experimental testing using automation tools, and statistical data processing. The study also examined the importance ranking of various quality criteria identified during the evaluation of different medical applications. The results demonstrate significant improvements in diagnostic accuracy and patient satisfaction through the use of electronic medical records and feedback systems. This article will be particularly valuable to healthcare professionals and software developers, including quality engineers and developers of medical applications, as well as researchers studying the impact of technologies on the medical industry. This work serves as a valuable resource for those aiming to enhance the quality and safety of medical services through innovative automation methods.
The Effect of Feeding Red Beans In Yoghurt On Organoleptic Acceptance And Protein Levels
Authors: Okfrianti Yenni , Lestari Putri Ayu , Yunita Yunita
Published: January 2025

Purpose: This study aims to examine the effect of red bean slurry addition on the organoleptic acceptance and protein content of yogurt. Methodology: The research employed a Completely Randomized Design (CRD) with one factor, namely variations in red bean slurry concentration. Organoleptic analysis was conducted using the Kruskal-Wallis test on attributes such as color, aroma, taste, consistency, and overall quality, involving 30 panelists. The most preferred product underwent protein content analysis using the micro Kjeldahl method. Results: Yogurt with 20% red bean slurry addition (F2) showed the highest organoleptic acceptance. The protein content of F2 yogurt increased from 0.56% to 1.30% after 24 hours of fermentation. Findings: The addition of 20% red bean slurry significantly enhanced the organoleptic acceptance and protein content of yogurt. Novelty: This study reveals the potential of red bean slurry as an additive to improve yogurt's organoleptic quality and protein content. Originality: This research contributes to the development of yogurt products enriched with red bean-based ingredients. Conclusions: Yogurt with 20% red bean slurry (F2) is the most preferred product, showing a significant increase in protein content after 24 hours of fermentation. Type of Paper: Experimental Research Paper.
An Analysis Of Income And Efficiency Of Robusta Coffee Farming In Lubuk Saung Village, Sebrang Musi Sub-District Kepahiang Regency
Authors: Anjarwati Meilinda Dwi , Nurmalia Ana , Fariadi Herri
Published: January 2025

Purpose: This study aims to analyze the income and efficiency of robusta coffee farming conducted by farmers in Lubuk Saung Village, Seberang Musi District, Kepahiang Regency. Methodology: The research was conducted in May 2024 using a quantitative descriptive method. The sample size was determined using the Slovin formula from a total population of 69 robusta coffee farmers. Results: The average robusta coffee production per hectare per year is 463 kg, generating a total revenue of IDR 27,786,086 annually. Average production costs are IDR 2,379,405.80, resulting in a net income of IDR 25,406,682 per hectare per year. Findings: The R/C ratio of 1.18 indicates that every IDR 1 spent generates IDR 1.18 in revenue. Originality: This research highlights the economic feasibility of robusta coffee farming. Novelty: It provides detailed financial analysis for local farming practices. Conclusion: Robusta coffee farming in Lubuk Saung is profitable and efficient. Type of Paper: Empirical research.
Analysis Business Feasibility of Saraba Traditional Beverage In Gorontalo Province
Authors: Murtisari Amelia , Blongkod Isra , Hippy Zubair
Published: January 2025

Purpose: This study aims to analyze the feasibility of saraba beverage businesses financially and non-financially in Gorontalo Province. Methodology: The study employed a quantitative descriptive approach through surveys using structured questionnaires. Samples were purposively selected, involving 16 saraba vendors and 30 consumers. Results: The analysis indicates that saraba beverage businesses are financially feasible with 12.5% R/C ratio > 1, 50% R/C ratio > 2, and 37.5% R/C ratio > 1. Finding: Non-financial feasibility is supported by a strong market potential with suggestions for flavor innovations, parking facilities, and educational promotions. Novelty: This study highlights the feasibility of saraba businesses through holistic financial and non-financial analyses, emphasizing sustainability and market development. Originality: The study provides strategic insights for saraba entrepreneurs to enhance local competitiveness. Conclusions: Saraba beverage businesses are feasible to develop, focusing on product innovation, consumer facilities, and promotions.Type of Paper: Empirical Research Article
Optimization Of Temperature And Time For The Quality Of Probiotic Yogurt Using Custom Incubator
Authors: Yannuarsita Deni , Prasojo Nugroho Dwi , Sasmito Moch Shandy
Published: January 2025

Purpose: This study aims to determine the best  temperature and time to incubate the yogurt making process by using a custom incubator as a fermentation tool for the quality of yogurt which includes the content of protein, fat, total acid, and lactic acid bacteria (LAB) Methodology: This study uses a Factorial Complete Random Design (RAL), the first factor is temperature (S1=36ºC, S2=39ºC, S3=42ºC) and the second factor is time  (T1=8 hours, T2=12 hours, T3=16 hours, T4=20 hours) each treatment is repeated three times, the data obtained is statistically analyzed using Analysis of Variance (Anova). If there is a real difference, it is continued with Duncan's New Multiple Range Test (DNMRT) at the level of 5% and 1%. Results: The temperature difference had a real effect (P<0.05) on the levels of protein, fat and LAB while the time difference had a real effect (P<0.05) on protein, fat, total acid and LAB. The interaction of temperature and time treatment had a real effect (P<0.05) on the content of Protein, Fat, Total Solid and LAB. Findings: The use of 39ºC temperature and 16 hours was able to produce a protein content of 3.77%, a total acid level of 0.85%, and a number of lactic acid bacteria of  8.99 log cfu/ml. Novelty: This study provides information that the combination of high temperature use and short time can speed up the incubation process. Originality: This study explains the effect of temperature and time on the quality of yogurt. Conclusion: high temperature and short time with custom incubator can produce yogurt according to SNI.  Document Type: Experimental Research Article
Influence of Non-Performing Loans, Lending rate and Financial Performance of Commercial Banks in Kenya. A Review of the Literature
Authors: Juma Otieno Ezekiel , Jemaiyo Beatrice
Published: January 2025

This study examined the impact of non-performing loans on the financial performance of publicly listed commercial banks in Kenya, focusing on the bank lending rate as a mediating variable. It analyzed the relationship between non-performing loans and banks' return on assets (ROA) and return on equity (ROE) through a review of empirical literature from Google Scholar and the Central Bank of Kenya reports. Studies show mixed results on the relationship between non-performing loans (NPLs) and bank performance. Previous studies have highlighted an inverse relationship between non-performing loans and return on assets (ROA), as noted by Siddique et al. (2022) and others. On the other hand, Mrindoko et al. (2020) discovered a negligible negative correlation with return on assets. Generally, the literature suggests an inverse relationship between NPLs and bank performance, emphasizing a diversified loan portfolio for improved profitability. Researchers have noted connections between NPLs and lending rates (Case et al., 2023; Rahmananingtyas, 2022; Koskei & Samoei, 2024), as well as between lending rates and bank performance (Hania & Himel, 2023; Dondi & Mule, 2023). This hypothesis suggests that lending rates play a mediating role in the relationship between non-performing loans (NPLs) and the financial performance of commercial banks in Kenya, highlighting the need for additional empirical research in this area.
Evaluasi Uprating Transformator Distribusi 20 KV pada Penyulang Kelinci di PT. PLN (Persero) ULP Rumbai
Authors: Usaha Situmeang  , Pangestu Aji , Monice Monice
Published: January 2025

The need for electrical energy affects the loading of the transformer which can result in overloading of more than 80%. PLN Standard No. 50 of 1997 states that a transformer is said to be overloaded if the load is more than 80%. This research aims to determine the effect of loading on transformer efficiency and voltage drop on distribution transformers. For loading on transformers before uprating, the results were 92.143%. The voltage drop percentage value obtained for each phase R, S, T is 11.121%, voltage drop percentage on the R phase, 10.973% voltage drop percentage on the S phase, 10.167% voltage drop percentage on the T phase. Uprating was carried out on the transformer to reduce overloading. After the uprating was carried out, the loading results were 55.568 % , which was in accordance with the permitted loading standards. The voltage drop percentage value obtained for each phase R, S, T is 10.973%, voltage drop percentage on the R phase, 10.524 % voltage drop percentage on the S phase, 9.637 % voltage drop percentage on the T phase.
EXPLORING THE GREEN-HRM LANDSCAPE: A DYNAMIC BIBLIOMETRIC DIVE INTO THE SCOPUS DATABASE
Authors: Kumar Vikas , - Versha , Jamwal Rajender
Published: January 2025

Green Human Resource Management is an HRM methodology that goes the extra mile to think outside the box and bring environmental sustainability into the picture regarding human resource activities. Managing human resources sustainably (GHRM) is a new term arising from the growing business movement to protect the environment. However, there are few bibliometric analyses of the development, trends, and collaborative networks in environmentally sustainable HR practices. The lack of this component emphasizes the need for the current inquiry. Biblioshiny and VOS Viewer software are used to answer the three research questions. Scopus database containing 357 records from 2000 to 2022 was used. Based on the data, 2019, 2020, 2021, and 2022 were highly productive years for GHRM paper publication. The study uses Scopus Database research documents to create visuals and tables. According to this data, the most referenced work in GHRM was Green Human Resource Management: A Review and Research Agenda, and the most cited author was Yusoff, Yusliza Mohd, from University Malaysia Terengganu in Malaysia. This study shows that service sector research is scarce. However, manufacturing studies are rising. Furthermore, GHRM research differs across developed and developing countries. Hence, cross-cultural and multicultural studies need to be prioritized.
Selection of optimal technique for greywater pretreatment
Authors: Taher Amer Hasan , Mosa Ahmed Mancy , Abdulrahman Lubna
Published: January 2025

Greywater can be reused after treatment. Several techniques for treating greywater can be adopted. However, the selection of the optimal technique is a difficult action. Therefore, this study adopted an experimental approach to compare two different techniques to determine the optimal one. Two systems were designed and constructed to study the optimal technique for greywater pretreatment. The first system consists of a 5000L anaerobic fiberglass tank of 2.5m depth whereas the other system consists of 5 separated cylindrical tanks; each tank of 1000L fiberglass. The pH, biological oxygen demand (BOD5), total suspended solids (TSS), Total N, Total P, chemical oxygen demand (COD), total organic Carbon (TOC), SO4, Alkaline, Na+1, Ca+2, K+1, and water temperature for raw greywater and effluent from each tank were continuously measured for ten months. According to performance data, ineffective anaerobic bacteria weaken wastewater in septic tanks by roughly 30–40% while extremely effective aerobic bacteria do the same in protonated tanks by more than 93%. Compared to anaerobic bacteria, aerobic bacteria enhance the quality of greywater that exits a septic tank. The present study exposed the nitrification of waste through aerobic treatment of greywater using ozone and air (1:1 volume %) to reduce odor, COD, TSS, and BOD5 and remove nitrogen.
Financial Feasibility Study of Middlemist Florist for Expansion
Authors: Christina Lorensia , Subiakto Subiakto , Anggono Achmad Herlanto
Published: January 2025

his study aims to evaluate the feasibility of Middlemist Florist’s business expansion by opening three new booths in strategic locations in Indonesia. Middlemist, as a leading player in the florist industry, has been operating since 2021, offering various fresh flower arrangements with exclusive designs. However, in the face of increasing competition, Middlemist needs to develop innovative business strategies to enhance revenue and expand its market reach. Using a quantitative approach, this study assesses the financial feasibility of Middlemist’s expansion by analyzing financial reports from 2021 to 2024, including income statements, balance sheets, and cash flow statements. Financial projections for the next five years were conducted to evaluate feasibility using methods such as Net Present Value (NPV), Internal Rate of Return (IRR), Profitability Index (PI), and Payback Period. The analysis revealed that the expansion project’s NPV is IDR 32.7 million, with an IRR of 66.52%, significantly exceeding the Weighted Average Cost of Capital (WACC) of 6.78%. Additionally, the PI value of 3.18 indicates substantial financial benefits compared to the initial investment cost. The Payback Period is estimated at only 1 year and 6 months, reflecting the efficiency and short-term profitability of this expansion. Sales projections indicate potential annual revenue of IDR 51.6 million per booth, with an average monthly sales target of IDR 4.3 million. This success relies heavily on Middlemist’s ability to capitalize on seasonal trends and customer demand for high-quality flower arrangements. However, the main challenges include competing with other florist businesses and maintaining high standards of quality and product innovation. This study recommends that Middlemist enhance its marketing strategies through digital approaches and collaborations with event organizers to expand its customer base. Revenue from the new booths should also be allocated to strengthening the operations of the main store and diversifying products to reach a broader market segment. Additionally, Middlemist should ensure sustainable operations by prioritizing environmentally friendly flower sourcing and supporting local farmers, aligning with the company’s vision. These findings suggest that expansion into three strategic locations not only has the potential to increase revenue but also strengthens Middlemist’s position in the growing florist industry in Indonesia. This study provides practical contributions to data-driven business strategy development, focusing on financial efficiency and business sustainability. This expansion is expected to be the first step in realizing Middlemist’s vision of being a premium flower provider that brings beauty and meaning to every important customer moment.
Skrining Probiotik Asal Produk Komersil yang Berpotensi Sebagai Inhibitor a-Glukosidase
Authors: Christin Angelin , Fachrial Edy
Published: January 2025

Various types of food products have good and bad effects on human health. One type of food that provides positive benefits is functional food. Functional foods are foods or beverages that are not only consumed to fulfill nutritional needs, but also provide good effects on the body's health and help reduce the risk of serious diseases. An example of functional food is probiotic drinks, which are known to support digestive health and strengthen the immune system. The content of probiotic drinks has a good impact on digestion and is able to inhibit α-glucosidase, so it is good to be consumed as a supplement for type 2 diabetes patients. The research focused on testing the potential of probiotics derived from commercial products on α-glucosidase enzyme activity. This type of research is laboratory experimental research with In Vitro method. The samples in this study are beverage samples with various types of brands containing probiotic milk that will be tested. The results showed that of the 8 probiotic isolates isolated from commercial products L-Bio, Yakult, Biokul and Max biotic have tolerance to acid and bile salt. Probiotic isolates in this study did not show antimicrobial activity. Screening of probiotics from commercial products with the most potential as α-glucosidase inhibitors was yakult.
Une progressive végétalisation des projets d’aménagement répond-elle aux enjeux de l’urbanisme durable ? Le cas de Lausanne
Authors: Jakob Fabien
Published: January 2025

Se focalisant sur la révision participative des plans directeur et d’affectation de la ville de Lausanne, cette recherche vise à saisir comment les éléments naturels, le végétal en particulier, sont pris en compte par les dispositifs de gouvernance, les stratégies d’adaptation des espaces urbains aux effets induits par les changements climatiques, les instruments réglementaires et techniques d’action publique en matière de planification et de gestion territoriales.
Remembering the XXVI SISET Congress and the 50th anniversary of its foundation, 2020
Authors: Tripodi Armando
Published: January 2025

SISET stands for the Italian Scientific Society for the Study of Thrombosis and Hemostasis. Founded in 1970, it currently enrolls more than 1,000 professionals across the country. Contributions by SISET scientists range from clinical to experimental investigations and are regularly published in leading international medical journals.
Pentecostal church leaders’ support to children in need of care and protection
Authors: Spaumer Andrew , Mavhandu-Mudzusi Azwihangwisi H.
Published: January 2025

Churches are considered one of the important structures responsible for providing care and support to vulnerable populations. One such population are children in need of care and support. This article presents the support provided by Pentecostal religious leaders to children needing care and protection. The study was conducted in Pentecostal churches in Tshwane Metropolitan Municipality, which is found in Gauteng province, South Africa. This qualitative study used an interpretative phenomenological analysis design. Data were collected from nineteen purposively selected leaders in Pentecostal churches using face-to-face semi-structured interviews. Data analysis was guided by the interpretative phenomenological analysis framework for data analysis. Findings indicate that religious leaders within Pentecostal churches are involved in providing care and support to children in need of care. The process they are engaged in include proper identification of those children, attending to physical, psychosocial and spiritual needs. However, each religious leaders use their approach depending on the relationship they have with members of government institutions such as police services and social workers. In order to enhance the support provided the children in need of care and protection, by religious leaders within Pentecostal churches, it is recommended that religious leaders are well informed about the role of different members of multidisciplinary teams such as social workers, psychologists, police officers, parents and other community structures. Moreover, there should be formalised collaboration and referral processes that will ensure that the child’s rights are not further violated in the process of provision of support.Contribution: The study contributes to the body of knowledge regarding the role Pentecostal church religious leaders are playing in child protection. Furthermore, it sheds light on the importance of a multidisciplinary approach to ensure that children in need of care and protection are holistically supported.
Twisted thinking and its relationship to radical thinking among university students
Authors: AL-Ogaidi Mohammed H.T.S. , Al-Dulami Yasir M.
Published: January 2025

Orientation: Twisted thinking and its relationship to radical thinking among university students.Research purpose: This study aimed to reveal the level of twisted and radical thinking, and to know the relationship between them among university students.Motivation for the study: To know the effects of these two negative types of thinking on students. These thoughts can cause a decline in their academic achievement and affect their social relationships within the university, leading to a waste of youthful energies.Research approach/design and method: This study used a descriptive approach on a random sample of 400 male and female students, in the second year in different specialisations, for the academic year 2023–2024.Main findings: It was found that the problem of second-year students in the colleges of the University of Mosul is that they possess twisted and radical thinking, and there is a strong direct relationship between these two types of thinking, which may cause a decline in their academic and social abilities in the future.Practical/managerial implications: The study highlights the impact of negative thinking patterns represented by twisted and radical thinking on students’ academic and social life, and the need to develop positive thinking skills to confront these negative thinking patterns.Contribution/value-add: This study contributes by providing data on deviant and radical thinking patterns among second-year students in the University of Mosul. Educational policy makers and curricula should include critical and positive thinking skills to ensure that these negative thinking patterns do not spread among students.