bluuebunny/crossref_metadata_2025 huggingface dataset:
Theta blocks
Authors: Gritsenko Valery , Skoruppa Nils-Peter , Zagier Don
Published: June 2024

We define theta blocks as products of Jacobi theta functions divided by powers of the Dedekind eta function and show that they give a new powerful method to construct Jacobi forms and Siegel modular forms, with applications also in lattice theory and algebraic geometry. One of the central questions is when a theta block defines a Jacobi form. It turns out that this seemingly simple question is connected to various deep problems in different fields ranging from Fourier analysis over infinite-dimensional Lie algebras to the theory of moduli spaces in algebraic geometry. We give several answers to this question.
Early monitoring values of oncogenic signalling molecules for hepatocellular carcinoma
Authors: Yao Min , Fang Rong-Fei , Xie Qun , Xu Min , Sai Wen-Li , Yao Deng-Fu
Published: June 2024

The prevention and early diagnosis of liver cancer remains a global medical challenge. During the malignant transformation of hepatocytes, a variety of oncogenic cellular signalling molecules, such as novel high mobility group-Box 3, angiopoietin-2, Golgi protein 73, glypican-3, Wnt3a (a signalling molecule in the Wnt/β-catenin pathway), and secretory clusterin, can be expressed and secreted into the blood. These signalling molecules are derived from different signalling pathways and may not only participate in the malignant transformation of hepatocytes but also become early diagnostic indicators of hepatocarcinogenesis or specific targeted molecules for hepatocellular carcinoma therapy. This article reviews recent progress in the study of several signalling molecules as sensitive biomarkers for monitoring hepatocarcinogenesis.
Simplified liver imaging reporting and data system for the diagnosis of hepatocellular carcinoma on gadoxetic acid-enhanced magnetic resonance imaging
Authors: Lyu Rong , Hu Wei-Juan , Wang Di , Wang Jiao , Ye Yu-Bing , Jia Ke-Feng
Published: June 2024

BACKGROUND

The liver imaging reporting and data system (LI-RADS) diagnostic table has 15 cells and is too complex. The diagnostic performance of LI-RADS for hepatocellular carcinoma (HCC) is not satisfactory on gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI).

AIM

To evaluate the ability of the simplified LI-RADS (sLI-RADS) to diagnose HCC on EOB-MRI.

METHODS

A total of 331 patients with 356 hepatic observations were retrospectively analysed. The diagnostic performance of sLI-RADS A-D using a single threshold was evaluated and compared with LI-RADS v2018 to determine the optimal sLI-RADS. The algorithms of sLI-RADS A-D are as follows: The single threshold for sLI-RADS A and B was 10 mm, that is, classified observations ≥ 10mm using an algorithm of 10-19 mm observations (sLI-RADS A) and ≥ 20 mm observations (sLI-RADS B) in the diagnosis table of LI-RADS v2018, respectively, while the classification algorithm remained unchanged for observations < 10 mm; the single threshold for sLI-RADS C and D was 20 mm, that is, for < 20 mm observations, the algorithms for < 10 mm observations (sLI-RADS C)and 10-19 mm observations (sLI-RADS D) were used, respectively, while the algorithm remained unchanged for observations ≥ 20 mm. With hepatobiliary phase (HBP) hypointensity as a major feature (MF), the final sLI-RADS (F-sLI-RADS) was formed according to the optimal sLI-RADS, and its diagnostic performance was evaluated. The times needed to classify the observations according to F-sLI-RADS and LI-RADS v2018 were compared.

RESULTS

The optimal sLI-RADS was sLI-RADS D (with a single threshold of 20 mm), because its sensitivity was greater than that of LI-RADS v2018 (89.8% vs 87.0%, P = 0.031), and its specificity was not lower (89.4% vs 90.1%, P > 0.999). With HBP hypointensity as an MF, the sensitivity of F-sLI-RADS was greater than that of LI-RADS v2018 (93.0% vs 87.0%, P < 0.001) and sLI-RADS D (93.0% vs 89.8%, P = 0.016), without a lower specificity (86.5% vs 90.1%, P = 0.062; 86.5% vs 89.4%, P = 0.125). Compared with that of LI-RADS v2018, the time to classify lesions according to F-sLI-RADS was shorter (51 ± 21 s vs 73 ± 24 s, P < 0.001).

CONCLUSION

The use of sLI-RADS with HBP hypointensity as an MF may improve the sensitivity of HCC diagnosis and reduce lesion classification time.
Hepatocellular carcinoma: An analysis of the expression status of stress granules and their prognostic value
Authors: Ren Qing-Shuai , Sun Qiu , Cheng Shu-Qin , Du Li-Ming , Guo Ping-Xuan
Published: June 2024

BACKGROUND

Hepatocellular carcinoma (HCC) is a global popular malignant tumor, which is difficult to cure, and the current treatment is limited.

AIM

To analyze the impacts of stress granule (SG) genes on overall survival (OS), survival time, and prognosis in HCC.

METHODS

The combined The Cancer Genome Atlas-Liver Hepatocellular Carcinoma (TCGA-LIHC), GSE25097, and GSE36376 datasets were utilized to obtain genetic and clinical information. Optimal hub gene numbers and corresponding coefficients were determined using the Least absolute shrinkage and selection operator model approach, and genes for constructing risk scores and corresponding correlation coefficients were calculated according to multivariate Cox regression, respectively. The prognostic model’s receiver operating characteristic (ROC) curve was produced and plotted utilizing the time ROC software package. Nomogram models were constructed to predict the outcomes at 1, 3, and 5-year OS prognostications with good prediction accuracy.

RESULTS

We identified seven SG genes (DDX1 , DKC1 , BICC1 , HNRNPUL1 , CNOT6 , DYRK3 , CCDC124 ) having a prognostic significance and developed a risk score model. The findings of Kaplan-Meier analysis indicated that the group with a high risk exhibited significantly reduced OS in comparison with those of the low-risk group (P < 0.001). The nomogram model’s findings indicate a significant enhancement in the accuracy of OS prediction for individuals with HCC in the TCGA-HCC cohort. Gene Ontology and Gene Set Enrichment Analysis suggested that these SGs might be involved in the cell cycle, RNA editing, and other biological processes.

CONCLUSION

Based on the impact of SG genes on HCC prognosis, in the future, it will be used as a biomarker as well as a unique therapeutic target for the identification and treatment of HCC.
Fine-needle aspiration technique under endoscopic ultrasound guidance: A technical approach for RNA profiling of pancreatic neoplasms
Authors: Seyfedinova Sabina Sherafedinovna , Freylikhman Olga Aleksandrovna , Sokolnikova Polina Sergeevna , Samochernykh Konstantin Aleksandrovich , Kostareva Anna Aleksandrovna , Kalinina Olga Viktorovna , Solonitsyn Evgeniy Gennadievich
Published: June 2024

BACKGROUND

Early diagnosis of pancreatic ductal adenocarcinoma (PDAC) has been a longstanding challenge. The prognosis of patients with PDAC depends on the stage at diagnosis. It is necessary to identify biomarkers for the detection and differentiation of pancreatic tumors and optimize PDAC sample preparation procedures for DNA and RNA analysis. Most molecular studies are done using paraffin-embedded blocks; however, the integrity of DNA and RNA is often compromised in this format. Moreover, RNA isolated from human pancreatic tissue samples is generally of low quality, in part, because of the high concentration of endogenous pancreatic RNAse activity present.

AIM

To assess the potential of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) to obtain specimens from pancreatic neoplasms for subsequent RNA molecular profiling, including next-generation sequencing (NGS).

METHODS

Thirty-four EUS-FNA samples were included in this study: PDAC (n = 15), chronic pancreatitis (n = 5), pancreatic cysts (n = 14), mucinous cysts (mucinous cystic neoplasia/intraductal papillary mucinous neoplasia) n = 7, serous cystic neoplasms n = 5, and pseudocysts n = 2. Cyst material consisted of cyst fluid and cyst wall samples obtained by through-the-needle biopsy (TTNB). Samples were stored at -80 °C until analysis. RNA purity (A260/230, A260/280 ratios), concentration, and integrity (RIN) were assessed. Real-time polymerase chain reaction was conducted on all samples, and small RNA libraries were prepared from solid mass samples.

RESULTS

RNA was successfully extracted from 29/34 (85%) EUS-FNA samples: 100% pancreatic adenocarcinoma samples, 100% chronic pancreatitis samples, 70% pancreatic fluid cyst samples, and 50% TTNB samples. The relative expression of GAPDH and HPRT were obtained for all successfully extracted RNA samples (n = 29) including low-quality RNA specimens. Low concentration and nonoptimal RIN values (no less than 3) of RNA extracted from EUS-FNA samples did not prevent NGS library preparation. The suitability of cyst fluid samples for RNA profiling varied. The quality of RNA extracted from mucinous cyst fluid had a median RIN of 7.7 (5.0-8.2), which was compatible with that from solid neoplasms [6.2 (0-7.8)], whereas the quality of the RNA extracted from all fluids of serous cystic neoplasms and TTNB samples had a RIN of 0.

CONCLUSION

The results demonstrate the high potential of EUS-FNA material for RNA profiling of various pancreatic lesions, including low-quality RNA specimens.
N-glycosylation of Wnt3 regulates the progression of hepatocellular carcinoma by affecting Wnt/β-catenin signal pathway
Authors: Zhang Xin-Zhan , Mo Xiao-Chuan , Wang Zhu-Ting , Sun Rong , Sun Da-Quan
Published: June 2024

BACKGROUND

Wnt/FZD-mediated signaling pathways are activated in more than 90% of hepatocellular carcinoma (HCC) cell lines. As a well-known secretory glycoprotein, Wnt3 can interact with FZD receptors on the cell surface, thereby activating the Wnt/β-catenin signaling pathway. However, the N-glycosylation modification site of Wnt3 and the effect of this modification on the biological function of the protein are still unclear.

AIM

To investigate the effect of Wnt3 N-glycosylation on the biological function of HCC cells.

METHODS

Site-directed mutagenesis was used to verify the Wnt3 N-glycosylation sites, actinomycin D treatment was used to detect the stability of Wnt3 after site-directed mutation, the binding of the N-glycosylation site-directed mutant Wnt3 to FZD7 was observed by laser confocal microscopy, and the effects of the N-glycosylation site-directed mutation of Wnt3 on the Wnt/β-catenin signaling pathway and the progression of HCC cells were detected by western blot and cell function experiments.

RESULTS

Wnt3 has two N-glycosylation-modified sites (Asn90 and Asn301); when a single site at amino acid 301 is mutated, the stability of Wnt3 is weakened; the binding ability of Wnt3 to FZD7 decreases when both sites are mutated simultaneously; and the level of proteins related to the Wnt/β-catenin signaling pathway is downregulated. Cell proliferation, migration and invasion are also weakened in the case of single 301 site and double-site mutations.

CONCLUSION

These results indicate that by inhibiting the N-glycosylation of Wnt3, the proliferation, migration, invasion and colony formation abilities of liver cancer cells can be weakened, which might provide new therapeutic strategies for clinical liver cancer in the future.
Balloon dilation of congenital perforated duodenal web in newborns: Evaluation of short and long-term results
Authors: Marakhouski Kirill , Malyshka Elena , Nikalayeva Katsiaryna , Valiok Larysa , Pataleta Aleh , Sanfirau Kiryl , Svirsky Aliaksandr , Averin Vasily
Published: June 2024

BACKGROUND

Incomplete congenital duodenal obstruction (ICDO) is caused by a congenitally perforated duodenal web (CPDW). Currently, only six cases of balloon dilatation of the PDW in newborns have been described.

AIM

To present our experience of balloon dilatation of a perforated duodenal membrane in newborns with ICDO.

METHODS

Five newborns who underwent balloon dilatation of the CPDW along a preinstalled guidewire between 2021 and 2023 were included. Nineteen newborns diagnosed with ICDO who underwent laparotomy were included in the control group.

RESULTS

In all cases, good anatomical and clinical results were obtained. In three cases, a follow-up study was conducted after 1 year. The average time to start enteral feeding per os was significantly earlier in the study group (4.4 d) than in the laparotomic group (21.2 days; P < 0.0001). The time spent by patients in the intensive care unit and hospital after balloon dilatation was also significantly shorter. We determined the selection criteria for possible and effective CPDW balloon dilatation in newborns as follows: (1) Presence of dynamic radiographic signs of the passage of a radiopaque substance beyond the zone of narrowing or radiographic signs of pneumatisation of the duodenum and small bowel distal to the web; (2) presence of endoscopic signs of CPDW; (3) successful cannulation with a guidewire performed parallel to the endoscope, with holes in the congenital duodenal web; and (4) successful positioning of the balloon performed along a freestanding guidewire on the web.

CONCLUSION

Strictly following selection criteria for newborns with ICDO caused by CPDW ensures that endoscopic balloon dilatation using a pre-installed guidewire is safe and effective and shows good 1-year follow-up results.
Steel, Corrosion-Resistant, Rivet Wire, 18Cr - 11.5Ni (SAE 305) Solution Heat Treated
Authors:   AMS F Corrosion and Heat Resistant Alloys Committee
Published: June 2024

This specification covers a corrosion-resistant steel in the form of wire.
‘Profit margins are determined by the need for companies to generate enough internal finance to pay for their investment’
Authors: Hein Eckhard , Lavoie Marc
Published: June 2024

Adrian Wood is Professor Emeritus of International Development at the University of Oxford. Among post-Keynesian economists, he is best known for his 1975 book, A Theory of Profits, which establishes a link between profit margins and growth rates. Wood was an undergraduate at King’s College in the University of Cambridge. After two years at Harvard University, he obtained his PhD in Economics in 1972 at Cambridge, and taught there until 1977. He then worked until 1985 at the World Bank, including five years on China, after which he joined the Institute of Development Studies at the University of Sussex, and later became Chief Economist of the UK’s Department of International Development. Wood was the guest of honour at the 2023 Lille Post Keynesian Conference.
Od naruszenia bezpieczeństwa przetwarzanych danych osobowych do nałożenia kary przez Prezesa UODO– zagadnienia praktyczne
Authors: Klich Aleksandra , Skrendo Bartosz
Published: June 2024

In the study, the authors focus on the practical aspects of personal data security management in the context of Polish legal regulations. They analyzed the concept of a personal data security incident and breach along with the necessary steps leading from a data security breach to the possible imposition of a penalty by the President of the Office for Personal Data Protection (UODO). The authors pointed out that to avoid sanctions, a personal data processor must not only comply with the minimum legal requirements but also focus on implementing measures to ensure an adequate level of security. The authors indicate the need for effective data protection through monitoring, rapid response to incidents and employee education. The authors point out that awareness of data security risks and effective preventive measures can help avoid sanctions from the President of the UODO. The conclusions of the publication provide a practical guide for data processors seeking to effectively protect personal data in a dynamic legal environment.
Prawo do sprzeciwu– szczególne uprawnienie decyzyjne podmiotu danych osobowych
Authors: Gudowska-Natanek Elżbieta
Published: June 2024

The article deals with the issue of a special decision-making right of the subject of personal data, which is the right to object to the processing of personal data by the data subject. The purpose of the study is not only to show the essence of this right, including the analysis of the conditions entitling the data subject to use the objection, administrator’s conduct, effects of making an effective request, as well as legal measures applicable in the event of rejection of the objection, but also to draw attention to the existing normative inaccuracies reflected in Regulation 2016/679. After reading the study, the readers will notice that the protection of the rights of the subject of personal data, without the help of a professional attorney, may not bring the expected results. The second emphasized aim of the study is of fundamental importance because ambiguous, hard-to-interpret, confusing, and highly formalized law is never helpful to the individual. Perhaps pointing out problems of a legal nature, which constitute specific postulates de lege ferenda, will cause a rational lawmaker to decide to introduce appropriate changes to the regulations.
Termin wymagalności roszczeń odszkodowawczych związanych z ograniczeniem sposobu korzystania z nieruchomości na terenie obszaru ograniczonego użytkowania
Authors: Jankowiak Tomasz
Published: June 2024

The author considers doubts relating to the date from which an indefinite claim arising from a restriction of the use of real estate in the area of limited usufruct is becoming due, which is regulated by Articles 129(2) and (3) and 136(3) of the Environmental Protection Law.
Firstly, the author presents primary conditions for establishing the area of limited usufruct. According to the author, the debtor, in the case of this type of claim, is well aware of its validity and can also easily verify it as to the amount. The author concluded that in the case of perpetual compensation claims related to the restriction of the use of real estate in a limited-use area, they become due when the debtor fails to provide without reasonable delay after the creditor calls on him to do so and from that moment statutory interest for delay should be awarded.
The Effectiveness of Using the SOLO Taxonomy in Acquiring Students the Concepts of Coordinate Geometry
Authors: Ghunaimat Mohammad A. , Alawneh Esraa Ahmed
Published: June 2024

Objective: The study aimed to investigate the effect of using the SOLO taxonomy levels on Prince Faisal Technical College students' acquisition of coordinate geometry concepts. To achieve the study's objective, Method: The researcher developed a test of acquisition of coordinate geometry concepts. The study used the semi-experimental approach with a pre-post design, and it was applied to (51) students from the college, who were divided into two groups: one experimental (25) student studied using the SOLO taxonomy levels, and the other controlled (26) students studied in the usual way. Results showed a positive effect of using the SOLO taxonomy as a strategy for teaching mathematics, especially in students' acquisition of concepts of coordinate geometry. The study recommended using the SOLO Taxonomy levels on students' acquisition of mathematical concepts in other fields such as algebra, statistics, etc. Novelty: This research presents novelty through the use of Solo taxonomy levels of classification in teaching mathematics, designing a teaching strategy to enable students to acquire concepts of coordinate geometry so that it is easy for teachers to implement this strategy in teaching mathematics.
Assessing the Complex Operation of Blended Learning for English Instruction in a Public High School in the Philippines
Authors: Sagun Danica Jae B. , Pawilen Greg T. , Paccarangan Sarah Jen C. , Albor Rufo Gil Z. , Patindol Hannah L. , Almeda Phrygian P. , Pelegrina Daisy V.
Published: June 2024

Objective: The study aims to describe stakeholders' experiences in blended learning at a public high school in Laguna, Philippines, during the COVID-19 pandemic. Method: This qualitative study was conducted through Focus Group Discussions (FGD) with English teachers, learners, and the Information and Communications Technology (ICT) coordinators and a Key Informant Interview (KII) with the English department head. Results: Three main themes emerged from the study: factors that encourage stakeholder collaboration, barriers to stakeholder collaboration, and solutions to collaboration challenges. Novelty: Overall, the study results show how important collaboration is in overcoming the difficulties associated with blended learning and creating a positive learning environment for the stakeholders. By fostering a collaborative environment, stakeholders can work together to address the complexities of blended learning, optimize the benefits of the modality, and create a compelling and engaging learning experience for all learners.
Autistic Student Teacher’s Pedagogical Competence in the English Language Teaching
Authors: Saputri Tiyas , Anam Syafiul , Munir Ahmad
Published: June 2024

Objective: This study aims to investigate the autistic student teacher’s pedagogical competence in the English Language Teaching (ELT) practicum based on eight teaching skills, the difficulties he faced, and the strategies to support the autistic student teacher applying his pedagogical competence in the ELT. Method: The method used was a descriptive qualitative with a case study approach. Data collection techniques used in this study were observation, interview, and video recording. Data analysis techniques were dividing observational field notes, doing data reduction, describing and identifying the activity of the autistic student teacher applying his pedagogical competence in the ELT practicums based on the eight teaching skills, and making a conclusion. Results:  The results of the study indicated that the autistic student teacher’s pedagogical competence in English Language Teaching based on the eight teaching skills in the eighth grade of inclusion class at 39 Junior High School Surabaya was good, although it was not successfully completed. It was obtained that he only did five to eight teaching skills. He had only skills in questioning, doing reinforcement, doing variation, explaining, opening and closing the class. Three teaching skills had yet to be fully mastered by him. The difficulties faced by him were classroom management, small group discussion and organizing small group discussion and individual work with the students. Novelty: This study focused on the autistic student teacher’s pedagogical competence in the English Language Teaching (ELT) practicum based on eight teaching skills. No study investigates the pedagogical competence of autistic student teacher in ELT, mostly the previous researches investigated the pedagogical competence of the student teacher with a normal condition.
FEATURES OF THERAPY FOR ADENOIDITIS IN CHILDREN WITH RESPIRATORY ALLERGOSIS
Authors: Карпищенко С.А. , Роднева Ю.А.
Published: June 2024

Cочетание гипертрофии аденоидов, риноаденоидита с другими заболеваниями верхних и нижних дыхательных путей, корреляция выраженности симптомов c иммунологическим и аллергологическим статусом ребенка, их взаимовлияние на степень проявлений симптомов являются актуальной проблемой. Поиск комбинированных методов лечения и контроль над полипрагмазией остаются ведущей задачей многих специалистов. В статье рассматриваются особенности течения, диагностики и лечения риноаденоидита при доказанном аллергозе. На основании анализа схожих клинических случаев показаны зависимость течения и успешность лечения данных патологий с применением антисептических и биорегулирующих средств.

The combination of adenoid hypertrophy, rhinoadenoiditis with other diseases of the upper and lower respiratory tract, the correlation of the severity of symptoms with the immunological and allergic status of the child, their mutual influence on the degree of manifestation of symptoms is an urgent problem. The search for combined treatment methods and control of polypharmacy remains the leading task of many specialists. In our article we consider the features of the course, diagnosis and treatment of rhinoadenoiditis with proven allergosis. Based on the analysis of similar clinical cases, we show the dependence of the course and success of treatment of these pathologies with the use of antiseptic and bioregulatory agents.
The Perceptions of Different Disciplines on Early Childhood Interprofessional Teams Involving Occupational Therapy Services
Authors: Martinez-Peraza Jessica , Milliken Natalie , Riley Bonnie
Published: June 2024

This phenomenological study was conducted to explore how professionals identify the roles of occupational therapy practitioners and other pediatric professionals on early childhood interprofessional teams. The use of surveys and interviews revealed three themes: 1) the role of occupational therapy encompasses more than what is perceived to be their role, 2) collaboration must be initiated, as it can be influenced by the setting, and 3) different professionals have the shared goal of promoting child health outcomes, but conflict can arise during collaboration. It was recognized that early childhood professionals would like to collaborate more with each member on the interprofessional team, but external influences and different settings for providing early childhood services may impact the ability to collaborate. This study discusses implications for occupational therapy professionals working in early childhood and the possibilities for future research.
Optimización de la gestión de inconformidades laborales, sector agroindustrial. Caso azucarero en Ecuador
Authors: Pullo Chuqui Silvia Vanessa , Tinto-Andrade Jaime , Solís-Muñoz Juan Bautista
Published: June 2024

El trabajo de titulación Optimización de la gestión de inconformidades laborales, sector agroindustrial. Caso azucarero en Ecuador parte desde la pregunta científica investigativa ¿Es posible la optimización de la gestión de inconformidades laborales en el sector agroindustrial? la cual actualmente se ve afectada por una administración inadecuada, generando impactos negativos en la estabilidad laboral. Así mismo el objetivo se centra en Determinar las dimensiones de la optimización de la gestión de inconformidades laborales en el sector industrial azucarero ecuatoriano mediante un paradigma positivista, con variables independientes como los conflictos laborales y dependientes en la optimización del clima laboral. El diseño metodológico adopta un enfoque cuantitativo, exploratorio, descriptivo y correlacional, utilizando encuestas con una muestra de 329 que se obtuvo del total de trabajadores de un Ingenio en Ecuador. El corte es transversal, probabilístico no experimental. Los resultados se basen a las respuestas obtenidas de las encuestas y a la pregunta científica planteada, así como también al objetivo general del estudio, revelando que la mayoría de los participantes son adultos ecuatorianos de entre 31 y 40 años, casados, y que trabajan en el sector agrícola, ganando entre 501 y 1000 dólares al mes, con un título básico y predominantemente de La Troncal. Los datos muestran que el país de procedencia, la experiencia en inconformidades, la escolaridad, el área de trabajo, el nivel de ingresos y el promedio de conflictos laborales tienen una asociación significativa con la percepción del clima laboral, mientras que el estado civil y la edad no influyen significativamente.
Preface
Authors: Campani Giovanna
Published: June 2024

Preface No. 16 (2023)
Istoria Didacticii Matematicii civilizației Indiei Antice
Authors: MARCHITAN Gabriela
Published: June 2024

The creation of Hindu mathematicians had an enormous influence on the subsequent evolution of arithmetic (the Hindu positional decimal number system), algebra (dispersion method for solving indeterminate equations of the first and second degree with two unknowns) and trigonometry (infinite strings for sine, cosine and arctangent). The earliest information with reference in Ancient India relates to the era of the composition of the philosophical-religious holy books "The Vedas".
Studierea Istoriei Didacticii Matematicii
Authors: COJOCARU Ion , HARITON Andrei , CALMUȚCHI Laurențiu
Published: June 2024

In order to expose in all its fullness the evolution of the History of Didactics and Mathematics, it is necessary to mark those premises that influenced the necessity of its appearance. These premises are geographical, chronological, social-economic-cultural, historical-archaeological monuments, mathematical monuments, remarkable problems from pop activity.
Istoria Didacticii Matematicii în contextul civilizației Chinei Antice
Authors: GHERMAN Gabriela
Published: June 2024

Chinese culture, including their mathematics, has very ancient and specific roots. Many of the most important discoveries in science and technology that have been made by Chinese scientists have long anticipated discoveries in other countries, especially Western Europe.
Analisis Hubungan Sektor Ekonomi Basis dengan Penyerapan Tenaga Kerja di Kabupaten Sidoarjo
Authors: Sagita Eka Aprilia N. , Imaningsih Niniek , Wijaya Riko Setya
Published: June 2024

This research aims to examine the relationship between the Basic Economic Sector and Labor Absorption for the 2018-2022 period. This research uses secondary data with a quantitative approach. The population in this study is data from the Annual Gross Regional Domestic Product Report for East Java and Sidoarjo Regency and data on Labor Absorption of Sidoarjo Regency. The sample used is annual Gross Regional Domestic Product data based on constant prices, basic sectors and labor absorption using a sample of the last 5 years, namely 2018 to 2022. The analysis method used in this research is the LQ method and data regression analysis method using SPSS software in carrying out data processing. The results of this research show that the Sidoarjo Regency Base Sector analysis in 2018-2022 produced 3 superior sectors, namely the Processing Industry Sector, the Electricity and Gas Procurement Sector, and the Transportation and Warehousing Sector. Meanwhile, the simultaneous results of the Base Sector variable have a significant effect on Labor Absorption. Partially, the Base Sector has a positive and significant effect on Labor Absorption. The Base Sector variable is able to explain variations in the Cooperative Capital variable of 98.4% and 1.6% is influenced by other factors not included in the research variables
DEVELOPMENT OF A RADIOMETER FOR MEASURING THE RADON CONCENTRATION IN THE AIR
Authors: Kovalenko G. , Karpus S. , Semisalov I. , Kapliy O. , Ovchinnik V. , Shulika M. , Shliakhov I. , Yalovenko V.
Published: June 2024

The results of the development of an experimental sample of a radiometer for measuring the concentration of radon in the air are presented. The application of an air pumping system and a combination of four Si planar detector plates made it possible to increase the sensitivity of the radiometer, which significantly expands its possibilities for use in both open and closed air ventilation systems. The developed software allows to measure and analyze the spectra of alpha particles in real time and evaluate the radon content in the specified time.
MODERNIZATION AND ADJUSTMENT OF THE MICROWAVE POWER CONTROL SYSTEM OF THE “ALMAZ-2M” ACCELERATOR
Authors: Zaleskyi D.Yu. , Pristupa V.I. , Us V.S. , Sotnikov G.V.
Published: June 2024

The microwave power source of the “Almaz-2M” accelerator is controlled by supplying a microwave modulated pulse from the “Rubin” master microwave generator to the KIU-12M klystron. The “Rubin” frequency must be adjusted to the resonant frequency of the accelerator, which may change under the influence of external conditions and aging of the materials of the accelerator elements, so it is necessary to adjust the “Rubin” frequency. At the same time, the “Rubin” frequency meter –“wave meter” also needs calibration. This paper describes a method for calibrating a “wave meter” with an accuracy of 1.5 MHz. For experiments on wakefield acceleration of an electron beam using a profiled sequence of bunches, it is important to synchronize all elements of the accelerator - the gun, the master oscillator, the klystron. For this purpose, a standard accelerator launch system was carried out. This made it possible to obtain trigger pulses with a rise time of about 200 ns. Also, based on modern microcircuits, a new trigger system with a leading edge of less than 100 ns has been developed.
COMPARISON OF STRUCTURAL DISRUPTIONS ON THE TUNGSTEN SURFACES WHICH INDUCED BY IRRADIATION OF HELIUM IONS BEAMS WITH ENERGIES 0.12 AND 4 MeV
Authors: Manuilenko O.V. , Prokhorenko E.M. , Pavlii K.V. , Zajtsev B.V. , Soshenko V.A. , Butenko V.I. , Prokhorenko T.G.
Published: June 2024

Helium ion beams with energies EHe+ = 0.12 and 4 МeV were used to irradiate samples of tungsten with a purity of 99.7%. Graphs of coefficient of the ionization, coefficient of production of phonon and vacancies are obtained. These processes occurred as a result of irradiation. The differential and integral curves of the sputtering coefficient
from the surface of samples of tungsten were constructed, that allowed to determine the number of recoil atoms that reached the surface. The total coefficients of displacements on the surface of the samples were calculated. These characteristics are compared with similar characteristics obtained by irradiating of samples of tungsten (tungsten samples) with a purity of 99.5% with helium ions (0.12, 4 MeV). Areas in which the characteristics are similar and areas where these characteristics differ are marked.
A RESEARCH ON NATIONAL POSTGRADUATE STUDIES WRITTEN IN THE FIELD OF KAZIEN COSTING
Authors: Önder Şerife
Published: June 2024

The increasingly competitive environment in business life causes businesses to adopt up-to-date approaches that will provide competitive advantage in the field of cost. For this reason, academic studies on cost accounting have become popular again in recent years. Kaizen costing approach is also one of the contemporary costing approaches. In this study, postgraduate thesis studies in the National Thesis Center of the Council of Higher Education (YÖK) were examined within the framework of bibliometric analysis, with the aim of being a guide for new studies in the relevant field. As a result of the examination, a total of 35 theses were identified. As a result of the bibliometric analysis, it was determined that 85% of the theses were prepared as master's theses. It has been determined that 83% of these universities are state universities. Although the first thesis on this subject was published in 1995, when compared in terms of publication years, it was seen that the numbers of theses were generally close to each other, although there were differences in some years.
Implementasi E-Government dalam Pelayanan Publik Bidang Administrasi Kependudukan di Kabupaten Karawang
Authors: Shadiq Dzaki Zaidan , Purnamasari Hanny
Published: June 2024

E-Government adalah penerapan teknologi inovatif untuk mengelola dan mengelola pemerintahan dan pelayanan publik secara efisien dan efektif. Hal ini melibatkan evaluasi terus-menerus terhadap kinerja birokrasi dan penerapan teknologi terintegrasi untuk meningkatkan komunikasi dan daya tanggap. Oleh karena itu, Dinas Kependudukan dan Pencatatan Sipil Kabupaten Karawang memperkenalkan layanan administrasi online mutakhir bernama E-Dukcapil. Tujuan penelitian ini adalah untuk mengkaji implementasi E-Government dalam penyelenggaraan pelayanan publik di Bidang Administrasi Kependudukan di Kabupaten Karawang. Penelitian ini menggunakan metode deskriptif kualitatif dengan menggunakan prosedur pengumpulan data berupa wawancara, observasi, dan dokumentasi secara langsung di Dinas Dukcapil Kabupaten Karawang. Hasil penelitian dilihat berdasarkan elemen penerapan E-Government bahwa implementasi E-Dukcapil tersebut masih kurang efektif sesuai indikator Support, Capacity dan Value, dikarenakan masyarakat memilih untuk melakukan proses pelayanan secara langsung
Article RETRACTED due to manipulation by the authors Analysis of Multiple Intelligence of Elementary Students in Physical Education Lessons in Yogyakarta Indonesia
Authors: Gani Ismail , Tomoliyus Tomoliyus , Hariono Awan , Pavlovic Ratko , Darmawan Arief , Shidiq Abdul Aziz Purnomo , Rahmatullah Muhammad Imam
Published: June 2024

The application of learning based on multiple intelligences has implications for collective awareness about diversity, uniqueness and equitable education. The objective of this study is to describe the level of multiple intelligences of students learning physical education in elementary schools, as well as to identify differences in the levels of each type of multiple intelligences based on the gender of the students.This study is a descriptive and comparative quantitative study. Purposive sampling was used to collect the samples. The 124 respondents included 57 male and 67 female students from Yogyakarta’s Syuhada Mosque Elementary School. The instrument employs a questionnaire comprised of 21 statements derived from the substance of multiple intelligences. The instrument employs a Likert scale of 1 to 4. The instrument was developed using theory, with expert consultation, and its validity and reliability were tested. Descriptive statistical data analysis used frequency distribution to describe the state of multiple intelligences, and non-parametric Mann-Whitney Test analysis used to determine differences in multiple intelligences based on gender. Based on the frequency distribution analysis, it was determined that the highest frequency of intelligence corresponds to the following criteria: the "low" category is in logical-mathematical (22.58%), the "moderate" category is in visual spatial (40.32%), the "high" criterion is in intrapersonal (58.06%), and the "very high" category is in bodily-kinesthetic (54.03%). According to the Mann-Whitney Test analysis, The value of Sig > 0.05 indicates that the hypothesis that elementary school male and female students learn physical education differently in terms of their multiple intelligences (musical, verbal linguistic, intrapersonal, visual spatial, interpersonal, bodily-kinesthetic, logical-mathematical) is rejected. Meanwhile, the hypothesis that male and female students have different levels of naturalist intelligence when learning physical education in primary schools is accepted because the Sig < 0.05. Elementary school students' levels of each type of multiple intelligence in physical education are quite variable. The Mann-Whitney Test analysis revealed that there was no significant difference in the level of multiple intelligences (musical, verbal-linguistic, intrapersonal, visual-spatial, interpersonal, bodily-kinesthetic, logical-mathematical) based on the gender of the students, but there were significant differences in the level of naturalist intelligence in learning physical education for elementary schools based on the gender of the students.
Key words: Multiple intelligence (MI), Students, Elementary School, Physical Education (PE)
Adolescents’ self-perceived health, life satisfaction and subjective vitality during the COVID-19 pan-demic: an analysis based on education level, gender and physical activity status.
Authors: Mata Carlos , Onofre Marcos , Papaioannou Athanasios , Martins João
Published: June 2024

During the COVID-19 pandemic, disruptions to adolescents' routines manifested in increased sedentary behaviors, reduced physical activity (PA), diminished social contacts, and adverse effects on mental health. The study's objective was to analyze and compare adolescents' self-perceptions concerning health, vitality, and life satisfaction based on gender, PA, and education levels during the pandemic's restrictive timeframe before the January 2021 lockdown. A total of 1369 Portuguese students (621 boys and 748 girls; Mage: 14.4 years; SD: 1.74) participated in this study. Group differences were analyzed via ANCOVA, considering age, standardized BMI, socioeconomic status, and daily moderate-to-vigorous PA both pre- and during the pandemic. Only 3.1% of adolescents adhered to international PA guidelines. Results indicated generally low levels of adolescents' health self-perceptions, particularly among girls. The study sheds light on adolescents' self-perceptions of health and well-being during the COVID-19 pandemic, emphasizing the associations between restrictive measures and adolescents' health perceptions and PA levels. Future studies are necessary to assess students' self-perceptions upon returning to normalcy and understand lingering negative effects on adolescents' well-being.
Keywords: Adolescents; self-perceived health; vitality; life satisfaction; physical activity; COVID-19.
The Effect of The Situated Game Teaching Model Through Set-Plays on Motor Development
Authors: Çakto Piyami , Akin Sinan
Published: June 2024

The purpose of this study, the effect of the situated game teaching model through setplays, which is an innovative model, on basic motor skills was investigated. In addition to the applications within the scope of the current curriculum, educational games applied for 8 weeks were conducted with situated game teaching model through setplays and their effects on basic motor skills were examined. Experimental and control groups included 62 2nd grade students in the 2020-2021 academic year. For 8 weeks, children were made to play with situated game teaching model through setplays 2 days a week and 40 minutes each. The short form of the second version of the Bruininks-Oseretsky Motor Proficiency Test (BOT-2) was used as a measurement tool. Prior to the applications, the first tests of both the experimental group and the control group were taken, and after the applications, the final tests of both groups were taken. After the normality test, repeated measures ANOVA and SIMPLE EFFECTS tests were applied for mixed measures at α=0.05 significance level to determine whether there was a difference between the basic motor development levels depending on the program applied to the study groups and the duration of the study. A statistically significant difference was found between the 6 subtests of BOT-2 (Fine Motor Sensitivity and Integrity, Balance, Running Speed and Agility, Hand-Arm Coordination, Power) and Total Motor Compound values. As a result, educational games applied and situated game teaching model through setplays positively affect basic motor skill levels.
Keywords: Situated game teaching, model, setplays, motor development, physical education.
Chronic effects of training and subsequent physical detraining on histology and morphometry of adipose tissue in adult Wistar rats
Authors: De Souza Alex , De Moraes Siqueira Gabriel , De Oliveira Campello Felix Anelize , Castilho de Barros Carlos , Xavier Cruz Luis Augusto , Bueno Orcy Rafael , Boscolo del Vecchio Fabrício
Published: June 2024

The objective of the study was to analyze the effects of physical exercise and subsequent detraining on histological and morphometric parameters of white adipose tissue (WAT) and brown adipose tissue (BAT). Also investigated were insulin and glucose tolerance. It was an experimental study with three groups: continuous moderate-intensity training (CMIT), high-intensity interval training (HIIT), and a control group (CG). Three assessments were carried out: pre-intervention, after 8 weeks of training, and after 4 weeks of detraining. A generalized estimation equation was performed for (group x moment), with Bonferroni post-hoc for group and moment in the analysis of adipocyte area and weight. A one-way ANOVA was performed to analyze the decay rate and the area under the curve between groups. For the intragroup study, repeated measures ANOVA with Bonferroni post-hoc was performed. An increase was observed between T2 and T3 in the area of perilumbar adipose tissue (747.3 ± 28.4 µm2 vs. 853.0 ± 15.7 µm2, p ≤ 0.01) and perirenal (770.3 ± 11.4 µm2 vs. 830 .9 ± 18.6 µm2, p ≤ 0.01) regardless of the group, as well as an increase in the subscapular BAT area from T1 to T3 (419.9 ± 38.5 µm2 vs. 751.8 ± 27.5 µm2, p ≤ 0.001). The weights of perirenal, perilumbar, and subscapular brown adipose tissues were lower in HIIT and CMIT compared to the CG (p ≤ 0.001). It was observed that after detraining, the calculation of the decline in glycemia showed a statistically significant difference (F = 8.79; p = 0.005) between CG and HIIT (0.78 % vs. 1.82 %), with a higher average percentage for HIIT. It is concluded that 8 weeks of CMIT and HIIT are efficient for weight control and adipose tissue area; however, this control is lost after 4 weeks of detraining, and even after this period, HIIT showed better insulin sensitivity.
Keywords: Exercise; Lipids; Adipose tissue; General adaptation syndrome; Supercompensation.
Moderate-intensity endurance training has higher effects suppression of oxidative stress secretion than strength training in obese students
Authors: Siantoro Gigih , Kartiko Dwi Cahyo , Muhammad Muhammad , Phanpheng Yanyong , Pramono Bayu Agung , Kusuma I Dewa Made Aryananda Wijaya , Triardhana Yanuar Alfan , Lestari Bhekti , Samudra Fajar Eka , Pranoto Adi
Published: June 2024

The objective of this research is to establish the impact of endurance training of moderate intensity and resistance exercises on the mitigation of oxidative stress in students with obesity. The research engaged a cohort of 30 female students, characterized by obesity, with an age average of 22.30±1.92 years and a Body Mass Index (BMI) averaging 31.77±2.72 kg/m2. These participants were randomly allocated into three distinct groups: the control group (CN, n=10), the group undergoing endurance training (ET, n=10), and the group subjected to strength training (ST, n=10). The intervention involving endurance training was executed at an intensity level of 60-70% HRmax, with each training session lasting between 40 to 60 minutes. Whereas, the strength training regimen was implemented with a load intensity of 60-70% 1RM, 4-6 sets, and 12-15 repetitions for each set. The intervention was administered with a regularity of three times per week for four weeks. Data collection was carried out by taking blood samples before and 24 hours after the last intervention—analysis of MDA levels utilizing the TBARs technique served as an indicator of oxidative stress. The technique employed for data analysis was the ANOVA test, then continued with the LSD post hoc test with a significant level (p≤0.05). The results showed that the average pre-MDA levels in CN, ET, and ST were (31.07±5.97, 32.12±8.91, and 31.36±8.52 ng/mL) respectively p=0.953. The mean post-MDA levels in CN, ET, and ST were (32.14±11.46, 15.21±8.01, and 22.02±7.33 ng/mL) respectively p=0.001. The mean delta MDA levels in CN, ET, and ST were (1.08±14.83, -16.91±9.68, and -9.34±7.51 ng/mL) respectively p=0.005. The average changes in MDA levels in CN, ET, and ST were (9.09±48.42, -51.71±24.77, and - 27.85±25.31 %) respectively p=0.002. Our findings revealed that both the endurance and strength training interventions resulted in a reduction of oxidative stress, as evidenced by the observed decrease in MDA levels following the training sessions. However, endurance training intervention has a higher effect on suppressing the secretion of oxidative stress than strength training in obese students.
Keywords: Endurance training, MDA levels, obesity, oxidative stress, strength training