bluuebunny/crossref_metadata_2025 huggingface dataset:
The Efficacy of a Forgiveness Bibliotherapy: A Randomized Controlled Trial with Nursing Students
Authors: Kim Jichan J. , Mullen Lora M. , Akers Shanna W. , Joseph Rachel A. , Bishop Lauren B. , Bistany Belle R. , Chambers Anita C. , Harvey Jerry R. , Houghton Aimee
Published: January 2022

Purpose of study: The need for forgiveness education for nursing self-care and forgiveness facilitation has risen. Therefore, the present pilot study tested the efficacy of an 8-week forgiveness bibliotherapy with a small number of undergraduate nursing students. Design of study: Matched pairs of nursing students were randomly assigned to either the experimental group or no-contact control group. The experimental group, using 8 keys to forgiveness by R. Enright (2015) as the treatment manual, read one chapter a week for 8 weeks and provided weekly reflections. Forgiveness and forgiveness-related outcome measures were administered at pretest, posttest, and one-month follow-up. Findings: At the posttest, the experimental group had significantly greater improvement in forgiveness compared to the control group with a large effect size, which was maintained at one month follow-up. There was no other significant difference between the two groups. Within-group comparisons of the experimental group showed improvement in forgiveness, anxiety, depression, and fatigue from pre to post testing periods and forgiveness, anger, anxiety, depression, and fatigue from pre to follow-up testing periods. Conclusion: Use of bibliotherapy may be a cost-effective way to promote the virtue of forgiveness for students in nursing programs.
An overview on Hebephrenia, a diagnostic cornerstone in the neurodevelopmental model of Schizophrenia
Authors: Maggini Carlo , Dalle Luche Riccardo
Published: January 2022

Pre-Kraepelinian observations converged in Kahlbaum’s and Hecker’s description of Hebephrenia. For Kraepelin, Hebephrenia was an ‘idiopathic incurable dementia whose onset is in adolescence’. It became the core of ‘Dementia Praecox’, and then Bleulerian ‘Schizophrenia’. In recent decades, the resurgence of the ‘late neurodevelopment’ hypothesis of schizophrenia has brought into focus Hecker’s clinical reports of adolescents who, as a result of a putative loss of psychic energy, showed a rapidly progressive cognitive impairment leading to functional and behavioural disorganization. This paper summarizes the nineteenth-century conceptualization of Hebephrenia as a developmental illness.
The Use of Digitalization (ICTs) in Achieving Sustainable Development Goals
Authors: Vyas-Doorgapersad S.
Published: January 2022

The article examines the use of information and communication technologies (ICT) in achieving sustainable development goals (SDGs). This link is conceptually and contextually analyzed in the global context whereby scholarly opinions and research works are discussed to substantiate the role that ICT can play in achieving SDGs. The article further examines the link in South Africa, using the country as a locus of the study. The article aims to find answers to the following research questions: How is ICT linked to all 17 SDGs? To what extent this link may accelerate SDGs’ implementation? What is the impact of ICT on accelerating SDGs? What are the challenges hampering the efficient utilization of ICT for SDGs’ implementation? The article uses a qualitative approach with desktop analysis to draw significant information. In addition, unobtrusive methods were applied, such as conceptual analysis and document analysis, to draw conclusions based on the findings. The findings confirm that despite ICT policies and infrastructure, the use and impact of ICT on SDGs is not always high. The article suggests that improvements are required at policy, institutional, department and individual levels. The suggestions can be applicable globally, based on the technological advancement and socio-economic development in country-specific contexts.
Credit Constraints and Increased Firm-Level Production Fragmentation: Evidence from India
Authors: Ghosh Debarati , Dutta Meghna
Published: January 2022

Previous studies have underlined various rationales for production fragmentation from wage differentials, decreased trade costs, access to specialized skills and resources, access to new markets, and benevolent government policies, to technological advancement. However, the idea that a firm’s financing structure can influence its production structure remains less explored, more so empirically. Firms that are financially constrained find it difficult to complete the entire production process in-house and therefore tend to resort to production fragmentation. The current study investigates this link between the extent of credit constraints faced by firms and their outsourcing behavior using data from Indian manufacturing firms over a period of ten years. We also separately study this linkage for firms that tend to export more vis-à-vis firms that export less, to ascertain if increased exporting have relaxed the financial constraint of the firms. The results confirm the positive effect of credit constraints on outsourcing behavior. For a robustness check, subsample regressions and alternative measures of constraints are also analyzed. The study has important policy implications for developing countries such as India, where outsourcing may prove to be a profitable reorganization strategy for firms that are financially constrained.
Acute hemorrhage and death in calves following chlorophacinone exposure
Authors: Radke Scott L. , Schrunk Dwayne E. , Ruane Abigail , Olsen Thomas , Burns Laura , Derscheid Rachel
Published: January 2022

Three calves were submitted to the Iowa State University Veterinary Diagnostic Laboratory for diagnostic evaluation following an abrupt increase in morbidity and mortality in a calf herd associated with epistaxis and widespread hemorrhage. Each of the submitted calves had moderate-to-severe hemorrhage within various tissues and body cavities, including the thymus, subcutaneous region of the neck, mediastinum, lungs, pericardial sac, heart, spleen, perirenal fat, urinary bladder, and skeletal muscle, including the diaphragm. An anticoagulant rodenticide screen was performed on the livers of each calf. Significant concentrations of chlorophacinone were detected at 4.2, 3.6, and 2.9 ppm in liver. Multiple piles and an open pail of white powdery material were present within the facility in which the calves were housed and were identified as the sources of chlorophacinone. Acute hemorrhage and death occurred in fourteen 1.5-mo-old, crossbred calves following ingestion of the vitamin K antagonist chlorophacinone.
Benign mixed Müllerian (duct) vaginal tumor in a 12-y-old goat
Authors: Hartung Svenja , Schlohsarczyk Elfi K. , Jost Alexandra , Sickinger Marlene , Köhler Kernt
Published: January 2022

In human and veterinary medicine, mixed Müllerian tumors (MMTs) are rarely diagnosed neoplasms of the tubular female genital tract. Although there are case reports of malignant MMTs in various species, benign MMTs have only been described once in a macaque. Here we present a case of benign MMT in a 12-y-old goat, and review the literature on uterine, cervical, and vaginal neoplasia in goats. The doe was presented with vaginal discharge and was euthanized because of the high suspicion of intraabdominal neoplasia. On gross examination, an ulcerated vaginal mass was identified. Histologically, 2 distinct cell populations were present: smooth muscle cells that were well differentiated and positive for alpha–smooth muscle actin, and ciliated columnar epithelial cells that lined ductal structures and had no signs of malignancy. These findings led to the diagnosis of neoplasia of Müllerian origin. Benign MMT should be considered as a differential diagnosis for uterine and vaginal neoplasms in goats.
Faculty Perspectives on the Master’s Degree in Music Education
Authors: Springer D. Gregory , Adams Kari , Nápoles Jessica
Published: January 2022

The purpose of this study was to examine music education faculty members’ perceptions of the master’s degree in music education (MME). A total of 76 music teacher educators completed a researcher-designed survey instrument. Participants believed their MME students’ top four motivations for pursuing MME degrees were to become a better teacher, to gain a higher salary, to create a possible pathway to doctoral study in the future, and to gain academic stimulation through graduate level coursework. Faculty also indicated the MME degree was focused on both teaching/pedagogy and research. Participants explained that their students primarily learn about research through reading and discussing research articles in class, and that their students learn about pedagogy primarily from reading pedagogical articles and reflecting on personal teaching videos. In addition, participants presented various opinions regarding the purpose of MME degrees. Implications for music teacher educators are discussed.
Associations of Atrial Fibrillation Patterns With Mortality and Cardiovascular Events: Implications of the MISOAC-AF Trial
Authors: Baroutidou Amalia , Kartas Anastasios , Samaras Athanasios , Papazoglou Andreas S. , Vrana Eleni , Moysidis Dimitrios V. , Akrivos Evangelos , Papanastasiou Anastasios , Vouloagkas Ioannis , Botis Michail , Liampas Evangelos , Karagiannidis Artemios G. , Karagiannidis Efstratios , Efthimiadis Georgios , Karvounis Haralambos , Tzikas Apostolos , Giannakoulas George
Published: January 2022

Aim:

This retrospective cohort study aimed to evaluate the prognostic implications of the distinct atrial fibrillation (AF) temporal patterns: first diagnosed, paroxysmal, and persistent or permanent AF.

Methods:

In this post hoc analysis of the MISOAC-AF trial (NCT02941978), a total of 1052 patients with AF (median age 76 years), discharged from the cardiology ward between 2015 and 2018, were analyzed. Kaplan-Meier and Cox-regression analyses were performed to compare the primary outcome of all-cause mortality, the secondary outcomes of stroke, major bleeding and the composite outcome of cardiovascular (CV) mortality or hospitalization among AF patterns.

Results:

Of patients, 121 (11.2%) had first diagnosed, 356 (33%) paroxysmal, and 575 (53.2%) persistent or permanent AF. During a median follow-up of 31 months (interquartile range 10 to 52 months), 37.3% of patients died. Compared with paroxysmal AF, patients with persistent or permanent AF had higher mortality rates (adjusted hazard ratio (aHR), 1.37; 95% confidence interval [CI], 1.08-1.74, P = .009), but similar CV mortality or hospitalization rates (aHR, 1.09; 95% CI, 0.91-1.31, P = .35). Compared with first diagnosed AF, patients with persistent or permanent AF had similar mortality (aHR, 1.26; 95% CI, 0.87-1.82, P = .24), but higher CV mortality or hospitalization rates (aHR, 1.35; 95% CI, 1.01-1.8, P = .04). Stroke and major bleeding events did not differ across AF patterns (all P > .05).

Conclusions:

In conclusion, in recently hospitalized patients with comorbid AF, the presence of persistent or permanent AF was associated with a higher incidence of mortality and morbidity compared with paroxysmal and first diagnosed AF.
Serum GDF-15 Predicts In-Hospital Mortality and Arrhythmic Risks in Patients With Acute Myocardial Infarction
Authors: Mo Qiuping , Zhuo Liuan , Liao Zhihong , Li Rongshan , Chen Yu , Geng Jianfang
Published: January 2022

This study aims to evaluate the association of serum growth differentiation factor 15 (GDF-15) with in-hospital mortality and arrhythmic risks in patients with acute myocardial infarction (AMI). A total of 296 consecutive patients with AMI were enrolled in our hospital from Jan. 2018 to Dec. 2020. Serum GDF-15 levels were measured at baseline. The primary endpoint was in-hospital all-cause mortality, and the secondary endpoint was major adverse cardiac events (MACEs) during hospitalization, defined as a composite of cardiovascular death, heart failure, sustained ventricular arrhythmias (ventricular tachycardia or ventricular fibrillation), and bleeding. During hospitalization, patients with a higher GDF-15 level had significantly higher incidences of in-hospital mortality (7.4% vs 1.4%; P = .02) and MACEs (9.5% vs 20.9%, P < .01) than those with a lower GDF-15 level. Multivariate logistic regression analysis showed that a higher GDF-15 level was significantly associated with increased risks of in-hospital mortality (OR = 1.92, 95% CI: 1.44-2.50; P < .01) and MACEs (OR = 2.19, 95% CI: 1.56-2.77; P < .01). In conclusion, GDF-15 was associated with the risks of in-hospital mortality and MACEs, indicating that it should be a prognostic biomarker for patients with AMI.
Vibration control of an unbalanced system using a quasi-zero stiffness vibration isolator with fluidic actuators and composite material: An experimental study
Authors: Solaiachari Sivakumar , Lakshmipathy Jayakumar
Published: January 2022

In this study, a new type of vibration isolator based on fluidic actuators and a composite slab was tested experimentally with an unbalanced disturbance. Quasi-zero stiffness vibration isolation techniques are advanced and provide effective isolation performance for non-nominal loads. The isolation performance of the proposed isolator was compared to that of a nonlinear vibration isolator equipped with fluidic actuators and a mechanical coil spring (NLVIFA). The NLVIFA system is better suited to non-nominal loads; however, the mechanical spring axial deflection leads to limited amplitude reduction in the system. To address this issue, a cross buckled slab was developed to replace a mechanical coil spring for absorbing vertical deflection by transverse bending, which is made of a specially developed composite material of Basalt fiber reinforced with epoxy resin and enhanced with graphene nano pellets. This current study was concerned with the theoretical analysis and experimental investigations of the proposed nonlinear vibration isolator with fluidic actuators and composite material (NLVIFA-CM), which performs under quasi-zero stiffness characteristics. Because of its reduced axial deflection, the theoretical and experimental results show that the NLVIFA-CM system outperforms the NLVIFA system and other linear type vibration isolators in terms of isolation performance. Furthermore, the proposed vibration isolator makes a significant contribution to low-frequency vibration.
Child Maltreatment and Substance Use: A Behavior Genetic Analysis
Authors: Azimi Andia M. , Connolly Eric J.
Published: January 2022

Child maltreatment is a pervasive social problem often perpetuated by family members and is related to a wide array of negative life outcomes. Although substance use is an outcome commonly associated with experiences of child maltreatment, not all individuals who experience maltreatment struggle with such issues. Many individuals can positively adapt to experiences of maltreatment based on levels of resilience and susceptibility. Research suggests that genetic differences may partly explain why negative outcomes develop for some, but not for others. Few studies have examined the extent to which genetic and environmental factors influence the longitudinal association between child maltreatment and varying forms of substance use, leaving a fundamental gap in our current understanding of this association. The current study aims to address this gap by analyzing a sample of twins from the National Longitudinal Study of Adolescent to Adult Health (Add Health). Findings from a series of univariate and bivariate biometric models reveal that the longitudinal associations between maltreatment, cigarette use, and marijuana use are accounted for by additive genetic and nonshared environmental factors. Moreover, the magnitude of the contribution varies across unique subgroups of cigarette and marijuana use. Directions for future research and theoretical implications are discussed.
News Sources and Framing of Responsibility on Devolution in Kenya, 2013–2017
Authors: Ochieng Jimmy
Published: January 2022

The present research examines two aspects of newspaper coverage of devolution during a 4-year period between March 27, 2013, and May 28, 2017: first, through the lens of attribution of responsibility, who the news media most blamed for problems facing devolution; second, whether reliance on official sources in reporting of devolution mirrors the indexing hypothesis. Findings show that the most-blamed actor and dominant news source on devolution is the county executive. Journalists continue to rely on the elite as their main news source and as a result they shape the discourse on devolution.
The emergence of b-cell maturation antigen (BCMA) targeting immunotherapy in multiple myeloma
Authors: Davis James A. , Shockley Abigail , Hashmi Hamza
Published: January 2022

Objective

Multiple myeloma, a plasma cell neoplasm is the second most common hematological malignancy in the United States. Despite significant advances in treatment armamentarium over the last decade, multiple myeloma remains an incurable malignancy. B-cell maturation antigen (BCMA) is an antigen expressed on the surface on plasma cells that can be targeted by novel mechanisms of action including antibody-drug conjugates (ADCs), bispecific T-cell engagers, and chimeric antigen receptor (CAR) T-cell therapy. This review summarizes the clinical application and development of approved and investigational immunotherapies targeting BCMA.

Data Sources

A search of the PubMed database was conducted using the following search terms: BCMA, CAR T, myeloma, belantamab mafodotin, and bispecific. Ongoing clinical trials, as well as abstracts from ASH and ASCO evaluating the efficacy and safety of novel agents targeting BCMA were evaluated. Prescribing information was also reviewed.

Data Summary

Since the discovery of BCMA as a target for myeloma, researchers have developed antibody-drug conjugates, bispecific T-cell engagers, and CAR T-cell therapies as novel treatment modalities for myeloma patients. Belantamab mafodotin and idecabtagene vicleucel represent currently available therapies and ongoing trials have demonstrated the efficacy and safety of bispecifics and other BCMA targeting therapies.

Conclusion

BCMA targeting antibody drug conjugates, bispecific T-cell engagers, and CAR T-cell therapies have demonstrated clinical activity in myeloma patients and represent novel therapies in multiple myeloma treatment paradigm.
Severe Generalized Weakness, Paraplegia following administration of Oxaliplatin in a patient with refractory T-cell non-Hodgkin lymphoma: A case report
Authors: Zarei B. , Moeini Nodeh M. , Arasteh O.
Published: January 2022

Introduction

Oxaliplatin is a third-generation platinum compound that used extensively for the treatment of various types of cancer especially gastrointestinal neoplasms. The main dose-limiting toxicities of oxaliplatin are hematological toxicity and peripheral sensory neuropathy.

Case report

A 42-year-old man with refractory peripheral T-cell lymphoma (PTCL) was admitted to receive GEMOX chemotherapy regimen (gemcitabine, oxaliplatin). Three days after receiving his third cycle of chemotherapy regimen, he was re-admitted to the emergency department with complaint of severe generalized weakness, and paraplegia in the lower extremities. According to clinical and para-clinical findings, chronic sensorimotor polyneuropathy with ongoing axonal loss was confirmed.

Management & Outcome

Intravenous dexamethasone 8 mg three times daily was started at the time of admission for the patient. Muscle weakness and sensory impairment improved dramatically within 10 days and the patient was able to walk with assistance.

Discussion

Several cases of neuropathy following oxaliplatin and only one case with gemcitabine-based chemotherapy regimen have been previously reported. However, motor symptoms are rare unless in the setting of acute neuropathy due to oxaliplatin. The most striking finding of our study was the incidence of a chronic sensorimotor axonaldemyelinating polyneuropathy in a patient who were subjected to oxaliplatin therapy. In conclusion, we report a case of severe generalized weakness and paraplegia following administration of Oxaliplatin.
Two-field variational formulations for a class of nonlinear mechanical models
Authors: Matei Andaluzia , Osiceanu Madalina
Published: January 2022

A nonlinear boundary value problem arising from continuum mechanics is considered. The nonlinearity of the model arises from the constitutive law which is described by means of the subdifferential of a convex constitutive map. A bipotential [Formula: see text], related to the constitutive map and its Fenchel conjugate, is considered. Exploring the possibility to rewrite the constitutive law as a law governed by the bipotential [Formula: see text], a two-field variational formulation involving a variable convex set is proposed. Subsequently, we obtain existence and uniqueness results. Some properties of the solution are also discussed.
Visual field changes in glaucoma patients after blepharoptosis surgery
Authors: Taniguchi Aya , Yunoki Tatsuya , Otsuka Mitsuya , Hayashi Atsushi
Published: January 2022

Purpose

To examine changes in parameters of the visual field test before and after blepharoptosis surgery in patients with glaucoma.

Methods

Twenty-three eyes of 14 glaucoma patients who underwent blepharoptosis surgery at Toyama University Hospital between July 2015 and September 2020 were included in this study. Pre- and post-operative values for the mean deviation (MD), pattern standard deviation (PSD) and total deviation (TD) of the upper or lower hemi-visual field in the Humphrey visual field test, best-corrected visual acuity (BCVA), intraocular pressure (IOP), and margin reflex distance (MRD)-1 were compared.

Results

MRD-1 showed a significant improvement after blepharoptosis surgery (preoperative MRD-1: 1.0 ± 0.82 mm, postoperative MRD-1: 3.26 ± 0.66 mm, p < 0.001). There were no significant differences in BCVA, IOP, MD and PSD values before and after surgery. On the other hand, there was a significant improvement in the superior TD (preoperative: −11.29 ± 6.57 dB, postoperative: −9.88 ± 7.31 dB, p = 0.044) although no significant difference was detected in the inferior TD postoperatively. The preoperative parameters of 2 groups (improvement and non-improvement groups of postoperative superior TD) were compared. Preoperative MD and superior TD were significantly lower in the improvement group (p = 0.03, p = 0.004, respectively), although there was no significant difference in preoperative PSD and inferior TD between the two groups.

Conclusion

In glaucoma patients, blepharoptosis may interfere with accurate visual field assessment, especially of superior TD.
Normative data on the foveal avascular zone in a young healthy Irish population using optical coherence tomography angiography
Authors: O'Shea Susan M. , O’Dwyer Veronica M. , Scanlon Grainne
Published: January 2022

Purpose

To establish normative data on the size, shape and vascular profile of the foveal avascular zone (FAZ) in a young, healthy, Irish population, using the Cirrus 5000 HD-OCT. Certain diseases may alter FAZ appearance. Normative databases provide normal baseline values for comparison, thus improving diagnostic ability.

Methods

One hundred and fifty-four subjects aged 18–35 years old were recruited. Superficial FAZ area, diameter, circularity, ganglion cell layer, central macular thickness (CMT), vascular perfusion and density were measured using the Cirrus 5000. Axial length was measured with the IOL Master and blood pressure was measured using the Omron sphygmomanometer.

Results

Mean FAZ area was 0.22 ± 0.07 mm2, mean CMT was 263.08 ± 18.73μm. Both were larger in females than males (p = 0.022, p = 0.000). Mean vessel density and perfusion central were 14.11 ± 2.77 mm/mm2 and 24.70 ± 4.96% respectively. Both were lower in females (p = 0.010, p = 0.019). Vessel density and perfusion inner correlated positively with minimum ganglion cell layer plus inner plexiform layer (GCL + IPL) thickness (p = 0.001, p = 0.019). CMT correlated positively with vessel density and perfusion central (p = 0.000 for both) and negatively with FAZ area (p = 0.000).

Conclusions

This study provides normative data for FAZ appearance and vascularity for the first time in a young, healthy, Irish population, using the Cirrus 5000 HD-OCT. Establishing machine and population specific normative data, particularly in relation to vessel density and perfusion is paramount to the early identification of ocular disease using Optical Coherence Tomography Angiography.
Frozen overnight: Acute orbital apex syndrome caused by aspergillosis
Authors: Pellegrini Francesco , Mandarà Erika , Stafa Altin , Meli Salvatore
Published: January 2022

Purpose

to describe a rare case of orbital apex syndrome caused by aspergillosis with acute presentation.

Case description

retrospective case report of a 70-year-old man who developed unilateral ophthalmoplegia overnight. He was initially given the diagnosis of suspect Tolosa-Hunt syndrome, but biopsy of the involved tissue showed aspergillosis.

Conclusion

orbital apex syndrome caused by fungal disease is a life-threatening condition that should be promptly diagnosed and treated. It may present acutely and should not be misdiagnosed as Tolosa-Hunt syndrome. To our knowledge this is the first such case report in the English ophthalmic language Literature.
Use of chronically occluded fistula to establish access outflow
Authors: Lagha Amal , Mallios Alexandros
Published: January 2022

Maintaining a good quality vascular access in the long term can become particularly challenging especially in patients that are on dialysis for many years and present with exhausted venous capital and chronic access related complications. We present a 60-year-old female patient with multiple bilateral previous failed accesses, a previous distal revascularization interval ligation (DRIL) for hemodialysis access induced distal ischemia (HAIDI). Her chronically (more than a month) occluded arteriovenous fistula AVF was used to establish outflow and create a functioning forearm arteriovenous graft (AVG).
High incidence of large bore temporary hemodialysis catheter malfunction in patients with COVID-19 related kidney injury
Authors: Shanmugasundaram Srinidhi , Kubiak Aleksander , Dar Aleena , Shrinet Abhishek , Chauhan Nirav , Haque Humza , Kumar Abhishek , Shukla Pratik A
Published: January 2022

Purpose:

To evaluate the incidence of large bore hemodialysis catheter malfunction in the setting of COVID-19.

Materials and methods:

A retrospective review was performed of all patients who underwent placement of a temporary hemodialysis catheter after developing kidney injury after COVID-19 infection at our institution. Data collected included demographic information, procedure related information, and incidence of replacement due to lumen thrombosis. Groups were compared using students t-test for continuous variables and Fisher’s exact test for nominal variables.

Results:

Sixty-four patients (43M, mean age 63.2 ± 13.3) underwent placement of temporary hemodialysis catheter placement for kidney injury related to COVID 19 infection. Thirty-one (48.4%) of catheters were placed via an internal jugular vein (IJV) access and 33 (52.6%) of catheters were placed via a common femoral vein (CFV) access. Overall, 15 (23.4%) catheters required replacement due to catheter dysfunction. There were no differences in demographics in patients who required replacement to those who did not ( p > 0.05). Of the replacements, 5/31 (16%) were placed via an IJV access and 10/33 (30.3%) were placed via a CFV access ( p = 0.18). The average time to malfunction/replacement was 7.8 ± 4.8 days for catheters placed via an IJ access versus 3.4 ± 3.3 days for catheters placed via a CFV access ( p = 0.055).

Conclusion:

A high incidence of temporary dialysis catheter lumen dysfunction was present in patients with COVID-19 infection. Catheters placed via a femoral vein access had more frequent dysfunction with shorter indwelling time.
Atypical presentation of fistula dysfunction due to brachial arterial embolization mimicking stroke
Authors: Vicente Rita , Rodriguez Laura , Vallespín Joaquim , Rubiella Carolina , Ibeas Jose
Published: January 2022

Vascular access thrombosis is an important complication with great impact on access patency and, consequently, on a patient’s quality of life and survival. We report the case of a 73-year-old woman with chronic kidney disease on hemodialysis with a radiocephalic arteriovenous fistula on the right arm that was brought to the emergency department with decreased strength in her right arm, ipsilateral hypoesthesia and facial hemi-hypoesthesia. The patient was given a brain computed tomographic scan that did not confirm suspicion of stroke. On re-examination, the patient had new-onset pain at arteriovenous fistula level, and her right arm was cold and pale. The nephrology department was called for arteriovenous fistula evaluation. On physical examination, her forearm fistula had a decreased thrill and arm elevation exacerbated its paleness. A bedside ultrasound was performed for arteriovenous fistula assessment. Doppler ultrasound revealed: partial thrombosis at brachial bifurcation, a flow of 80–105 mL/min at brachial artery level and a radial artery with a damped waveform. Anastomosis and draining vein were permeable. In this case, the diagnosis of acute embolic brachial artery occlusion was made by a fast bedside ultrasound evaluation. The patient underwent thromboembolectomy with Fogarty technique, recovering fistula thrill, radial and cubital pulses. Thromboembolism of the fistula feeding artery is a rare cause of vascular access thrombosis and it is rarely mentioned in the literature. In this report, failure to recognize the upper limb ischemia would have led to delayed treatment, potentially resulting in the fistula’s complete thrombosis and further limb ischemia. We highlight the importance of a diagnosis method like Doppler ultrasound, which allows for rapid evaluation at the patient’s bedside.
Distance that the catheter covers from skin to the vein using the US-guided in-plane technique: The impact of footprint of the probe and depth of the vein
Authors: Uzumcugil Filiz
Published: January 2022

Employing the in-plane technique in infants the footprint of the ultrasound probe should be considered along with the depth of the vein, and the angle between the needle and the face of the probe, which is crucial in optimization of the visibility of the needle in the beam. Three different ultrasound probes are evaluated for different depths of vein. The hockey-stick probe provided a shorter minimum distance while maintaining the angle between the needle and the face of the probe within an optimal range for visualization of the needle in the beam, supporting its recommendation for infants with regard to its frequency and physical size.
When do political parties listen to interest groups?
Authors: Røed Maiken
Published: January 2022

This paper examines when parties listen to interest groups and adopt their input. Interest group information can help parties bolster their positions, and by taking their input into account, parties show that they are responsive to the groups’ interests which can increase their appeal to their constituents. Listening to interest groups can, however, also repel voters who disagree with the groups’ positions. This paper argues that party and issue-level characteristics affect whether the benefits of listening to interest groups exceed the costs. Examining more than 25,000 party-interest group observations on 88 Norwegian policy proposals and using a text reuse approach to measure interest group influence, the findings indicate that public salience, party issue emphasis, interest group coalitions, and government status affect parties’ propensity to listen. This implies that interest groups can be a pertinent source of information for parties under certain circumstances which affects the link between voters and parties.
Experimental investigation of seismic performance of a novel isostatic frame-cladding system
Authors: Chong Xun , Huo Pu , Xie Linlin , Jiang Qing , Hou Linbing , Xie Jinchen
Published: January 2022

A new connection measure between the precast concrete (PC) cladding panel and PC frame structure is proposed to realize a new kind of isostatic frame-cladding system. Three full-scale PC wall-frame substructures were tested under the quasi-static load. These substructures included a bare wall-frame specimen, a specimen with a cladding panel that has no opening, and a specimen with a cladding panel that has an opening in it. The damage evolution, failure mode, load-bearing capacity, deformation capacity, and energy dissipation capacity of three specimens were compared. The results indicated that the motions of the cladding panels and the main structures were uncoupled through the relative clearance of the bottom connections, and three specimens exhibited approximately identical failure modes and seismic performance. Thus, the reliability of this new isostatic system was validated.
Charity and grace
Authors: Pina-Cabral João
Published: January 2022

This essay attempts to reconcile charity with grace, the central concepts of two thinkers whose views may seem irreconcilable to many: Donald Davidson, an analytical philosopher and the most distinguished follower of Quine; and Julian Pitt-Rivers, an Europeanist anthropologist, who wrote at length on Spain and Southern France. The latter's historicist exegesis of gracia points to basic aspects of human experience that are also salient in the reduction to basics that Davidson carried out concerning interpretation and truth. For Davidson, in the face of ultimate indeterminacy, interpretation is made possible due to the rational accommodation that charity sparks off. For Pitt-Rivers, gratuity highlights how processes of personal interaction depend on the drawing of shared trajectories: that is, not only do I have to grant others charity to make sense of them, I also have to frame others as subjects with a future by relation to myself as already in existence. The paper proposes that human interaction involves processes of sensemaking that integrate shared intentionality (i.e. the credit with which we respond to the indeterminacy of meaning) with shared experience (i.e. the debt implicit in the ultimate underdetermination of the world's entities). Thus, it brings both concepts together under the label of charis, their common etymological root, suggesting that the dynamic it represents is a broader feature of life itself.
One donor egg and ‘a dollop of love’: ART and de-queering genealogies in Facebook advertising
Authors: Reed Elizabeth , Kant Tanya
Published: January 2022

We consider what genealogical links, kinship and sociality are promised through the marketing of assisted reproductive technologies (ARTs). Using a mixed method of formal analysis of Facebook's algorithmic architectures and textual analysis of twenty-eight adverts for egg donation drawn from the Facebook Ad Library, we analyse the ways in which the figure of the ‘fertile woman’ is constituted both within the text and at the level of Facebook's targeted advertising systems. We critically examine the ways in which ART clinics address those women whose eggs they wish to harvest and exchange, in combination with the ways in which Facebook's architecture identifies, and sorts those women deemed of ‘relevance’ to the commercial ART industry. We find that women variously appear in these adverts as empowered consumers, generous girlfriends, potential mothers and essentialised bodies who provide free-floating eggs. The genealogical and fertility possibility offered through ART is represented with banal ambiguity wherein potentially disruptive forms of biogenetic relatedness and arrangements of kinship are derisked by an overarching narrative of simplicity and sameness which excludes men, messy genealogies and explicitly queer forms of kinship. This rationalisation is supported by the simplicity and certainty of the Facebook targeted advertising algorithm which produces a coherent audience and interpellates users as fertile subjects whose choices are both biologically determined and only available through clinical intervention.
Does Innovative Millennial Entrepreneurship have a role in fostering cyber learning on business performance? A perspective of entrepreneurial agility
Authors: Hindrawati Gita , Dhewanto Wawan , Dellyana Dina
Published: January 2022

Millennials have the uniqueness of active learners and work with freedom. Millennials are the first generation to put the fun in work-life. Social media is a strategic instrument in Cyber Learning (CL) in work-life and lifestyle. Learning on Business Performance (BP) in many studies has an insignificant effect and is still inconclusive. The purpose of this study is to offer Innovative Millennial Entrepreneurship (IME), which will be tested empirically in its role in pushing CL to BP significantly. Data collection was carried out by employing a purposive sampling method on 159 millennials who hold owner/manager positions in business organizations. Data analysis used a quantitative approach with Structural Equation Modelling (SEM). The empirical results in the model provide evidence that IME fully mediates, becoming a bridge that strongly fosters the role of CL (β = 0.83) on BP (β = 0.42) and Marketing Capability (MC) through Agile Teamwork (AT) provides an excellent total effect when compared with the direct effect between CL (β = 1.01) and BP (β = 0.79). In the Entrepreneurial Agility perspective, IME and MC through AT have encouraged millennials CL to be converted into better performance through opportunity foresight, systemic insight, and entrepreneurial mindset.
Open innovation, dynamic organizational capacities and innovation performance in SMEs: Empirical evidence in the Tunisian manufacturing industry
Authors: Chabbouh Hajer , Boujelbene Younès
Published: January 2022

In this paper, the main objective is to examine inbound open innovation adoption by exploring its antecedents in terms of dynamic organizational capabilities, its implications on innovation performance, but also its mediating role between these capabilities and Small and Medium Enterprise (SME) innovation performance. Therefore, a conceptual model was proposed and empirically tested on the basis of data extracted from a survey involving a sample of 228 Tunisian manufacturing SMEs and analyzed through the Structural Equation Modeling method. In doing so, this paper adds to the existing literature on open innovation in SMEs and fills a neglected theoretical gap by proposing a link between dynamic capabilities theory and the open innovation paradigm, two literatures that have little overlap, to improve current understanding of innovation performance in SMEs. Ultimately, by empirically confirming the significant relationship between dynamic organizational capacities and innovation performance through the mediating role of open innovation, our results are mainly relevant for entrepreneurs and innovation managers in SMEs who can find valuable guidance on how to strengthen innovation performance under the nexus between the dynamic capabilities perspective and open innovation by focusing on the development of three capabilities that are dynamic capabilities, absorptive capability, and appropriation capabilities.
Classical deterrence theory revisited: An empirical analysis of Police Force Areas in England and Wales
Authors: Abramovaite Juste , Bandyopadhyay Siddhartha , Bhattacharya Samrat , Cowen Nick
Published: January 2022

The severity, certainty and celerity (swiftness) of punishment are theorised to influence offending through deterrence. Yet celerity is rarely included in empirical studies of criminal activity and the three deterrence factors have never been analysed in one empirical model. We address this gap with an analysis using unique panel data of recorded theft, burglary and violence against the person for 41 Police Force Areas in England and Wales using variables that capture these three theorised factors of deterrence. We find that the three factors affect crime in different ways. Increased detection by the police (certainty) is associated with reduced theft and burglary but not violence. We find that variation in the celerity of sanction has a significant impact on theft offences but not on burglary or violence offences. Increased average prison sentences (severity) reduce burglary only. We account for these results in terms of data challenges and the likely different motivations underlying violent and acquisitive crime.
Evaluation of Effect of Biologically Synthesized Ethanolic Extract of Propolis-Loaded Poly(-Lactic-co-Glycolic Acid) Nanoparticles on Wound Healing in Diabetic Rats
Authors: Tayfeh-Ebrahimi Reza , Amniattalab Amir , Mohammadi Rahim
Published: January 2022

Wound healing is interaction of a complex cascade of cellular/biochemical actions leading to restoration of structural and functional integrity with regain of injured tissues strength. This study was aimed at evaluation of application of ethanolic extract of propolis-loaded poly(-lactic-co-glycolic acid) nanoparticles (EEP-PLGA NPs) on wound healing in diabetic rats. Sixty rats were randomized into four groups of 15 rats each: In control group (Control) diabetic wound was treated with normal saline. In Carrier 1 group diabetic wound was treated with PLGA nanoparticles based solution. In Carrier 2 group the diabetic wound was treated with EEP. In Treatment group animals received EEP-PLGA NPs on the wound. Wound size was measured on 7, 14 and 21 days after surgery. The expression of p53, bcl-2, Caspase III, were evaluated using reverse-transcription PCR and Immunohistochemical staining. The Treatment group had significantly reduced the wound size compared to other groups ( P = 0.001). histological and morphometric studies, and mean rank of the qualitative studies demonstrated that there was significant difference between Treatment group and other groups ( P < .05). Observations demonstrated that ethanolic extract of propolis-loaded PLGA nanoparticles significantly shortened the inflammatory phase and accelerated the cellular proliferation. Accordingly, the animals in Treatment group revealed significantly ( P < .05) higher fibroblast distribution/one mm2 of wound area and rapid re epithelialization. The mRNA levels of bcl-2, p53 and caspase III were remarkably ( P < .05) higher in Treatment group compared to control and animals. The immunohistochemical analyzes confirmed the RT-PCR findings. EEP-PLGA NPs offered potential advantages in wound healing acceleration and improvement through angiogenesis stimulation, fibroblast proliferation and granulation tissue formation in early days of healing phases, acceleration in diabetic wound repair associated with earlier wound contraction and stability of damaged area by rearrangement of granulation tissue and collagen fibers.
Shakespeare’s Staged Trials
Authors: Leubsdorf John
Published: January 2022

The trials in Shakespeare’s plays are strange. There are no lawyers or professional judges, there may be no witnesses, and the adjudicator often imposes unusual sanctions such as banishment. Most strikingly, almost all the trials are fakes, manipulated by a character toward a predestined result. Two obvious explanations—that trials in Shakespeare’s day were like that, and that trials in the contemporary drama were like that—turn out to be largely incorrect. It is more persuasive to trace the strange features of Shakespeare’s trials to the various dramatic functions they fulfill, yet even this approach does not explain everything.
The psychological role of music and attentional control for religious experiences in worship
Authors: Walter Yoshija , Altorfer Andreas
Published: January 2022

This study investigated the psychological dynamics during worship experiences under the influence of different music conditions. In total, 60 believers were recruited to participate in experiments where they were asked to engage in worship and to connect with God while continuously ranking how strongly they sensed the presence of the divine. After each condition, they were asked to rate how well they were able to focus on God during the worship procedure. Based on a previously published Feedback Loop Model that portrays global psychological mechanisms in worship, we deduced two hypotheses: (1) the ability to focus on God is positively associated with how strong the subjective religious experience becomes, and (2) the different musical conditions yield varying degrees in the intensity of the felt presence of God. Our statistical analyses on the current sample demonstrate that both alternative hypotheses can be accepted. For the latter thesis, two further assumptions were at play: (1) we speculated that religious worship songs were associated with stronger divine experiences than with secular ones, and (2) it was assumed that if they could worship to their own selection of songs, the experience would be more powerful than with the ones that were provided by the research team. Whereas upon our investigation the former assumption can be deemed correct, the latter shows a positive but insignificant association.
Asymmetry in internal oblique muscle thickness: Not the key to a cricket fast bowler's performance
Authors: Olivier Benita , Olivier Franso-Mari , Mnguni Nkazimulo , Obiora Oluchukwu Loveth
Published: January 2022

Purpose

Previous studies found that trunk muscle asymmetry may play a role in preventing injury in cricket fast bowlers, while the association with bowling performance has not been investigated. This study aims to describe the side-to-side differences in trunk muscle thickness and determine the association between bowling performance and these side-to-side differences in trunk muscle thickness in adolescent fast bowlers.

Methods

In this observational cross-sectional study, bowling performance, namely ball release speed and bowling accuracy, was recorded in adolescent fast bowlers. Ultrasound imaging measured external oblique, internal oblique, transversus abdominis and lumbar multifidus muscle thickness.

Results

Fast bowlers (n = 46) with a mean age of 15.9 (±1.2) years participated. On the non-dominant side, the external oblique and internal oblique at rest were thicker than on the dominant side (external oblique: p = 0.011, effect size = 0.27; internal oblique: p < 0.0001, effect size = 0.40), while the transversus abdominus ( p = 0.72, effect size = 0.19) and lumbar multifidus ( p = 0.668, effect size = 0.04) were symmetrical. Weak correlations existed between bowling performance and the side-to-side differences in the thickness in all muscles, except for two moderate correlations: 1. The smaller the side-to-side difference in absolute thickness of the external oblique when contracted, the faster the ball release speed (Spearman's (ρ) = −0.455, p = 0.002). 2. Also, a smaller side-to-side difference in external oblique contraction ratio (Spearman's (ρ) = −0.495, p = 0.0001) was associated with faster ball release speed.

Conclusions

No relationship between bowling performance and side-to-side differences in internal oblique muscle thickness could be established, while more symmetrical external oblique muscles may be linked to faster ball release speeds.
Breaking up the play: The relationship between legal stops and winning in team handball
Authors: Laxdal Aron , Ivarsson Andreas
Published: January 2022

The purpose of this study was to examine the relationship between legal stops and winning in team handball. Real-time analysis was performed on all games played in the Icelandic elite division for both males and females (regular season and playoffs) between 2017–2021 (854 games [570 male games, 284 female games], 32,392 legal stops in total). Legal stops were assessed as any physical action by a defensive player that resulted in the stop of play, without the defensive player being penalized or the offensive player receiving a 7-meter throw. The results from a multinomial logistic regression analysis indicated that legal stops were significantly associated with winning games in the male league. No statistically significant relationship was found between illegal stops and game outcome for either sex. However, 2-minute suspensions were found to be positively associated with winning in the male league.