bluuebunny/crossref_metadata_2025 huggingface dataset:
Serotonylation of the Rho Family GTPases: Investigation in Neuronal Cell Models
Authors:   , Allen Samuel
Published: April 2022

Serotonin is a well-known monoamine neurotransmitter that displays a wide range of biological activities, one of which is protein serotonylation. In this process serotonin is covalently linked to a protein by the calcium-dependent activity of the enzyme Transglutaminase-2. Many different proteins can be serotonylated, ranging from extracellular proteins such as fibronectin, to intracellular proteins such as the small GTPases. This investigation focused on the Rho family of small GTPases, in particular the proteins RhoA, Rac1 and Cdc42, which all have roles in modulating the polymerisation activity of the actin cytoskeleton. These proteins can be serotonylated, which leads to their constitutive activation. It is thought that these changes in activity play a role in altered dendritic spine morphologies seen in neuropsychiatric disorders. This thesis examined the serotonylation of these three GTPases in neuronal cell culture models using Liquid Chromatography Tandem Mass Spectrometry techniques. Additionally, the chemical synthesis of the serotonin analogue O-propargylserotonin was investigated for its application to detect serotonylation using Immunocytochemistry and Western Blotting methodologies. The results of the Liquid Chromatography Tandem Mass Spectrometry investigation indicated that there was no serotonylation of the GTPases RhoA, Rac1 and Cdc42 under the conditions applied, and that this may be due to the absence of specific receptor stimulation events. Investigation of O-propargylserotonin synthesis indicated that there were inconsistencies with the published methods, which required an alternate methodology to be used.
Design of Rice Dryer Automation System Using Fuzzy MIMO Method
Authors: Rahardi Gamma Aditya , Widjonarko Widjonarko , Utomo Satryo Budi Utomo
Published: April 2022

Rice is one of the most important cultivated plants in human civilization. One of the most important post-harvest processes is drying. Therefore, we need a drying process with an artificial heat source that can be adjusted to achieve constant heat according to the temperature characteristics of the rice. By applying the Fuzzy-MIMO control system, rice drying is expected to work quickly without damaging the rice foam. Fuzzy-MIMO system is translated into a rule based on the fuzzy algorithm that has been created. The fuzzy-MIMO method used is the Sugeno method with input temperature errors and humidity errors and outputs in the form of heat and wind gusts. The temperature sensor used has an error factor of 3.61%. The expected control system is a heating system and a motor to regulate the wind gusts in the drying chamber. The total drying time produced is 240 seconds with a moisture content of 15.2%. Drying time is influenced by the initial moisture content of rice.
La percepción, la cognición y la interactividad
Authors: Freré Arauz Jesennia Susana , Véliz Gavilanes Johanna Paola , Sarco Alemán Evelina Mariley , Campoverde Jimenez Kerly Jasmín
Published: April 2022

La percepción es uno de los procesos cognitivos, capaz de captar, procesar y dar sentido de forma activa a la información que alcanza nuestros sentidos, mientras que la cognición organiza y da sentido a la actividad, al pensamiento, al razonamiento, a la acción, y a diferentes formas de relación de las personas con el mundo y con la información que obtiene de él. La interactividad, por su parte, es la comunicación entre mínimo dos actores que tiene lugar a través de un circuito de mensajes coherentes separados y consistente. El propósito fundamental de la presente investigación es plasmar un compendio de los aspectos relacionados con la percepción (sensorial), la cognición y la interactividad, principalmente mediante el uso de las tecnologías de comunicación e información (TIC) en los procesos cognitivos. La investigación se realizó bajo una metodología de tipo documental bibliográfica, bajo la modalidad de revisión. De la revisión se desprende que los procesos cognitivos de las personas ciertamente son racionales, no obstante, no se puede negar su dependencia de los estímulos exteriores que influyen en los sentidos y que permiten el proceso cognitivo. Elementos como la imagen, el sonido, el color, entre otros, llevan al ser humano al conocimiento de su entorno. En este sentido, tal y como lo explica el empirismo, se comienzan a formar ideas como un reflejo de la realidad que se percibe. El proceso de aprendizaje resulta más efectivo en aquellos casos donde se estimulan los sentidos en comparación con un texto plano. El avance de la educación debe ir a la par con la tecnología, por cuanto ofrece diferentes herramientas que permiten estimular los sentidos de manera individual o combinada para el aprendizaje. Asimismo, las nuevas TIC facilitan la interactividad entre el usuario y la información, pasando de un mero procedimiento mecánico en el acceso de la información a desarrollar un proceso cognitivo en quien interactúa y aprende.
History of Mathematics in High School: a proposal for didactic material based on (and despite) the Common Core
Authors: Jelin Daniel Fernandes , Venezuela Antonio Luís
Published: April 2022

This article examines the notorious contrast between the importance given in and outside the classroom to the use of History of Mathematics in teaching Mathematics. Based on that, we propose a framework of didactic material that encourages the use of historical elements in the fulfillment of the Brazilian Common Core for High School (BNCC-EM). The material consists of a historical recount, related to certain skill, and mathematical tasks inspired by it. We also present one example supported by three seminal contributions from the 17th century, due to Michael van Langren, Christiaan Huygens, and Edmond Halley. Throughout recount and tasks, we emphasize the use of History of Mathematics for the study of mathematical procedures and concepts, about which the BNCC-EM itself, contrary to previous milestones in Education, says nothing
Ensino de Física e escalas de distâncias astronômicas
Authors: Arruda Higor Felipe Gonçalves de , Teixeira Ricardo Roberto Plaza
Published: April 2022

O principal objetivo deste artigo é refletir sobre as possibilidades de um trabalho educacional em torno do tema das escalas de distâncias astronômicas, de modo a contribuir com a melhoria do ensino de Física. Foram analisadas três escalas astronômicas e as respectivas ordens de grandeza das medidas envolvidas: distâncias interplanetárias, distâncias interestelares e distâncias intergalácticas. Para isso, foram descritas algumas das principais unidades para medir comprimentos em escalas astronômicas e investigados os métodos básicos de determinação de distâncias em Astronomia. Foram descritas e investigadas algumas possibilidades de estratégias didáticas, tendo como eixo temático o estudo de escalas de distâncias astronômicas. Foram também apontadas e sucintamente caracterizadas algumas ferramentas disponíveis na internet úteis para atingir este propósito. Essa é, portanto, uma pesquisa exploratória e qualitativa sobre recursos didáticos com o intuito de analisar as possibilidades de seu uso educacional
SISTEM PEMBELAJARAN JARAK JAUH GURU PENDIDIKAN JASMANI OLAHRAGA DAN KESEHATAN (PJOK) SELAMA PANDEMI: KEUNTUNGAN, KENDALA DAN SOLUSI
Authors: Wahyudhi Andi Sultan Brilin Susandi Eka
Published: April 2022

Pandemi Covid-19 yang telah terjadi di beberapa negara masih tetap berlanjut hingga di tahun 2021 hingga batas waktu yang tidak menentu. Khusus bagi guru PJOK pembelajaran yang selama ini dilakukan dengan tatap muka berubah menjadi tatap maya (synchronous). Guru yang profesional harus dapat mengatasi semua masalah yang ada dalam pembelajaran. Jenis penelitian ini adalah penelitian deskriptif kualitatif. Teknik pengumpulan data menggunakan teknik observasi, Wawancara dan Dokumentasi. Populasi dalam penelitian ini adalah guru PJOK SMA. Sampel penelitian ini yaitu 20 orang dengan menggunakan teknik kuota sampling. Hasil yang diperoleh Keuntuangan yang didapat yaitu Pembelajaran tetap terlaksana dimana saja dan kapan saja, terhindar dari virus, lebih mengenal teknologi, materi pembelajaran bisa diakses dimana saja, dan lebih banyak berkumpul dengan keluarga dirumah. Kendala pembelajaran Jarak jauh yaitu kebiasaan malas mandi, jaringan yang tidak stabil, paket data yang terbatas, perangkat pembelajaran yang rusak, tidak semua materi pembelajaran bisa dilakukan, pemberian tugas tidak maksimal, pengawasan dan evaluasi dalam pembelajaran tidak maksimal serta mata mudah lelah. Solusi yang bisa di berikan yaitu Merubah RPP luring menjadi daring, penilaian diturunkan, durasi tugas dalam membuat video tidak harus lama, tidak harus sering melakukan tatap maya, pembelian perangkat pembelajaran untuk dipinjamkan ke peserta didik.Pandemi Covid-19 yang telah terjadi di beberapa negara masih tetap berlanjut hingga di tahun 2021 hingga batas waktu yang tidak menentu. Khusus bagi guru PJOK pembelajaran yang selama ini dilakukan dengan tatap muka berubah menjadi tatap maya (synchronous). Guru yang profesional harus dapat mengatasi semua masalah yang ada dalam pembelajaran. Jenis penelitian ini adalah penelitian deskriptif kualitatif. Teknik pengumpulan data menggunakan teknik observasi, Wawancara dan Dokumentasi. Populasi dalam penelitian ini adalah guru PJOK SMA. Sampel penelitian ini yaitu 20 orang dengan menggunakan teknik kuota sampling. Hasil yang diperoleh Keuntuangan yang didapat yaitu Pembelajaran tetap terlaksana dimana saja dan kapan saja, terhindar dari virus, lebih mengenal teknologi, materi pembelajaran bisa diakses dimana saja, dan lebih banyak berkumpul dengan keluarga dirumah. Kendala pembelajaran Jarak jauh yaitu kebiasaan malas mandi, jaringan yang tidak stabil, paket data yang terbatas, perangkat pembelajaran yang rusak, tidak semua materi pembelajaran bisa dilakukan, pemberian tugas tidak maksimal, pengawasan dan evaluasi dalam pembelajaran tidak maksimal serta mata mudah lelah. Solusi yang bisa di berikan yaitu Merubah RPP luring menjadi daring, penilaian diturunkan, durasi tugas dalam membuat video tidak harus lama, tidak harus sering melakukan tatap maya, pembelian perangkat pembelajaran untuk dipinjamkan ke peserta didik.
Myths and Realities of Modern Art Education
Authors: Oleksiuk Olga
Published: April 2022

The article considers the state of scientific understanding the pedagogical mythology, which is aimed at searching the genesis of myths, the peculiarities of development in terms of artistic educational communication. The author of the article considers that, within the theory and practice of modern art pedagogy, “old pedagogy” is in conflict with the new reality. Regulation, standardization, optimization and competence approach became the necessary aspects of a new pedagogical mythology. The special philosophy of education appears that follows standards of the digital society. In the context of digital renewal of the modern art education, it is necessary to analyse the failed experience of innovation activity in order to model the best ways to improve the situation
REMOTE WORK WITH CHOIR UNDER PANDEMIC CONDITIONS
Authors: Zeman Aleksandra
Published: April 2022

The classes of the Choir module in the Department of Artistic Education in Musical Art belong to the block of subjects which aim at the development and education of vocal abilities of choristers through improvement of voice emission and work on musical interpretation of vocal and vocal-instrumental pieces diversified in terms of texture and style. This class prepares for collaborative presentations of planned artistic endeavors.
The article describes a remote work with a choir operating in the Institute of Musical Arts of the Faculty of Arts and Sciences of Education in Cieszyn at the Silesian University in Katowice. The COVID-19 pandemic forced academics to look for new methodological solutions. In spite of many inconveniences and shortcomings, especially the lack of direct contact with the students or an important concert presentation of their achievements, I consider this time with full responsibility as extremely important in the musical development of students. Working on performance, emission and interpretation problems of the realized repertoire, recording the effects of the work required great commitment from the conductor, the leaders in the voices as well as all choristers. I am extremely grateful to the Choristers of the Musical Arts Institute Choir for their commitment and serious approach to new challenges.
Development of Aural Recall of the Novice Singers in Musical and Theoretical Cycle Classes
Authors: Merezhko Yuliya , Khodorovska Iryna
Published: April 2022

The article reveals the peculiarities of the development of aural recall of the novice singers in musical and theoretical cycle classes in higher education institutions. It is found that the development of the young people’s abilities for music, a component of which is the aural recall, influences the development of their music culture as an important and integral part of the whole intellectual culture of each individual.
In the process of writing the article, the following theoretical methods of research were used: analysis of psychological, pedagogical and musical literature on the problem under study, systematisation, content analysis, generalisation and formulisation of its conceptual provisions and conclusions. The analysis of the works of scientists on the definition of such concepts as “aural recall”, “ability for auditory perception”, “musical and rhythmic sense” has been conducted. The main abilities for music that make up the structure of musicality has been considered (according to B. Teplov). The essence of the concept of “distinction of mode functions of sounds” has been specified. The main characteristics of musical sound are outlined: absolute and relative pitch. It has been established that, depending on which characteristics of sound formed the basis of solfeggio, the appropriate methodological systems for the education of ear training
have been formed: absolute and relative. The musical and pedagogical system of “conscious musical singing” — “Stalbitza” (“Stairs”) by the Bulgarian educator Borys Trychkov has been substantiated. It has been specified that in the process of development of aural recall of the novice students the musical notation plays a big part. Methods and techniques for the development of aural recall of the novice singers
in the disciplines “Theory of Music”, “Solfeggio”, “Harmony”, “Analysis of Musical Form” have been suggested, namely: relative solfeggio, solmization, singing of melodic and harmonic exercises, writing of elementary musical dictations. Methodical pieces of advice on the development of pure intonation of the novice vocalist students in the process of vocal and performing activity have been given. The general conclusion of the article is the opinion of the scientists that the more active and colorful the musical activity of novice students in the disciplines of musical and theoretical cycle is, the more effective the process of their musical development will be, and it will contribute to the development of their musiс culture.
Implementation of the Instrumental and Performing Experience of Students in Concert Activities
Authors: Ekonomova Olga , Harkusha Lyudmyla
Published: April 2022

The article is devoted to the problem of students’ upbringing of active musicizing in the process of their performing activity. The aspects of improving the performing level and artistic and aesthetic development of students are considered. It is studied the students’ attitude to musical and artistic activity, to stage performance, which is the main component of fulfilment of a musician’s need to communicate and
involve the listeners to the process of communicating with a piece of music. The necessary pianistic skills, various methods of preparation for a concert performance and for the process of pop performance of musical works are shown. The author considers the integrity of the perception of a musical work, the implementation of the synthesis of author’s and performing ideas, sound material and the search
for its transmission to the listener, the analysis of factors that help professional, creative skill. The formation of a culture of professional-pedagogical and stage communication, the accumulation of relevant experience by students, due to the expansion and interaction of subjects of learning is shown. All this will give an impetus for a high level of communication between the teacher-student, the performer-listener and the achievement of mastery in professional, creative and performing activities. The basis of the student’s performing activity has always been the need to feel with the listener, and therefore the article very specifically shows the communicative aspects of musical performance.
The Professional and Personal Qualities of Music Teacher as a Research Subject
Authors: Malakhova Marharyta
Published: April 2022

The article’s relevance arises from the tasks of higher education to train a competent competitive specialist in the field of art education, which is characterised by the appropriate professional and personal qualities, as well as the ability to apply them in educating students through music. The goal of this article is to determine the essence and structure of a music teacher’s professional and personal qualities through the analysis of philosophical, psychological-pedagogical, and musical-methodical works.
The research methodology is founded on the complex application of methods of analysis (of scientific literature to determine teachers’ productive professional and personal qualities), generalisation (of theoretical provisions for the development of future teachers’ professional and personal qualities), and synthesis (of scientific theory and practice in order to determine the nature and structure of professional and personal qualities of this specialist). It is noted that the essence and structure of a music teacher’professional and personal qualities should be determined by taking into account the specifics of music and pedagogical activities and teachers’ social status, educational values and educational value of music, professional erudition and teaching competency, teachers’ pedagogical talent and creativity. The study’s findings include the author’s definition and the structure of a music teacher’s professional and personal qualities. A music teacher’s professional and personal qualities are defined as a complex of professional and pedagogical, musical and creative, social and personal competency characteristics that are developed during the learning and professional activity process and ensure their effectiveness. Three dominant components represent the structure of a music teacher’s professional and personal qualities:
1) professional and pedagogical qualities (professional motivation, education and value orientation, pedagogical tact, pedagogical style, professional image); 2) musical and creative qualities (musicality and musical talent, musical and methodical ability, creativity, musical and performing mobility, stage adaptability); 3) socio-personal qualities (social activity, emotional stability, character traits, erudition,
authority and leadership). It has been ascertained that the professional and personal qualities of a music teacher are competency characteristics, which ensures the effectiveness of music teaching and creative music activities
Kurgu ile Ütopya Arasında: Habermas’ın Dine Yaklaşımında Değişim ve Post-Seküler Toplum Projesi
Authors: DERELİ Mustafa Derviş
Published: April 2022

Sekülerleşme konusu, sosyolojinin en verimli tartışma alanlarından biri olarak son yarım asırdır ciddi düzeyde fikri kamplaşmalara sahne olmaktadır. Sosyolojinin kurucu isimlerinin dinin geleceğine yönelik kehanetleriyle temelleri atılan sekülerleşme literatürü, dine daha fazla alan açan modern dönem sosyologların farklı yaklaşımlarıyla zenginleşmeye devam etmektedir. Sosyal bilimlerin pek çok alanıyla bir şekilde irtibatı bulunduğu için disiplinler arası bir mahiyete sahip olan bu literatürde kimi kavram ve yaklaşımlar daha fazla ön plana çıkarken, kimi görüşler diğerleri kadar etkili olamamıştır. Bilhassa Türkçe literatürde yeterince irdelenmemiş sekülerleşme yaklaşımlarından biri de “post-seküler” kavramsallaştırmasıdır. 1950’lerin sonlarından itibaren bazı sosyal teologların çalışmalarında karşılaşılmakla birlikte söz konusu kavramı daha geniş düzeyde tartışmaya açan sosyolog, Jürgen Habermas olmuştur. Habermas, 2000’lerden sonra yazdığı pek çok metninde, özellikle Avrupa toplumları gibi belirli sekülerleşme süreçlerinden geçmiş ülkelerin “post-seküler” bir aşamaya geçmekte olduklarını, böylelikle toplumda dünya görüşü açısından çeşitlenen seküler ve dindar vatandaşların ortak bir uzlaşı noktasında buluşmaları gerektiğini ileri sürmektedir. Habermas’ın post-seküler toplum projesini sorunsallaştıran bu makale aynı zamanda din fenomenine yaklaşımında entelektüel bir dönüşüm yaşayan Habermas’a dair bir portre çıkartmayı hedeflemektedir. Literatür taraması yönteminin kullanılacağı bu çalışma; muğlak olduğu, ütopik veçhelerinin bulunduğu ve Avrupa-merkezci bir perspektif sunduğu gibi birtakım eleştirilerle karşılaşan “post-seküler toplum” kavramı etrafında geniş çaplı bir değerlendirme yapmayı amaçlamaktadır. Birtakım açmazları bulunmakla birlikte post-seküler toplum adlandırmasının, seküler-dini (kutsal) dikotomisini aşmak ve meseleyle ilgili daha kuşatıcı bir perspektif geliştirmek adına önemli görülmesi gerektiği sonucuna ulaşan bu makale, bilhassa ülkemiz literatüründe dine yönelik bakışı son derece ihmal edilen Habermas’ın konuyla ilgili analizlerine bir din sosyoloğu olarak daha fazla başvurulması gerektiğine dikkat çekmektedir.
Law as Anti-Kinship: The Colonial Present in Global Surrogacy
Authors: Van Wichelen Sonja
Published: April 2022

Law and regulation are often seen as the panacea for the ills of science and markets: regulation minimizes risks by setting out clear rules, calls out abuses when those rules are not obeyed, and disciplines actors, institutions, and states to behave according to collectively agreed upon principles. In this article I challenge this liberal narrative of regulation by looking at how cross-border surrogacy arrangements are currently debated in private international law. I first demonstrate that technosciences are intimately linked to regulatory and legal frameworks. Here, recombinant knowledge has led to new formations of legal parenthood while obscuring other forms of kinship in quite paradoxical ways. Second, the liberal story of law and regulation erodes the history and political economy in which law has come to represent itself as universal and moveable. I examine how a gendered, racialized, and (post)colonial context of global fertility chains is lost in the legal instruments designed to protect the people involved in international surrogacy arrangements, preferring instead neoliberal forms of kinship. Finally, the liberal story of law also embraces the story of individualism. I show the conflicts that arise when such individualist forms of law are transplanted to non-individualist contexts, both in non-Western and Western contexts. I argue that by subjecting non-liberal others (across the Global North-South divide) to bioethical frameworks that intervene in kinship ontologies, private international law runs the risk of prolonging the logic of colonial and imperial thinking.
Slave Episteme in Biocapitalism
Authors: Weinbaum Alys Eve
Published: April 2022

This article explores the connection between the extraction and dispossession of human reproductive labor power and its products in the contexts of Atlantic slavery and contemporary biocapitalism.  It argues that the conceptualization and practice of slave reproduction that sustained slave racial capitalism is forwarded into the biocapitalist present through “the slave episteme.”  This becomes evident when reproduction in biocapitalism is viewed through the lens of the long history of slave “breeding” in the Atlantic world. While the “blackness” that enslavers attributed to enslaved mothers and their progeny objectified and dehumanized both and rationalized their treatment as fungible and alienable commodities, in contempory biocapitalism the racial formation that subtends reproductive extraction and dispossession has been complexly recalibrated to do related ideological and material work. The article concludes with a discussion of the sublation of “blackness” in contemporary market exchanges in which reproductive labor and its products are bought and sold.
Transplacental and Molecular Migrations: Methyl Isocyanate Gas and Reproductive Bioeconomies in Bhopal
Authors: Roy Deboleena
Published: April 2022

In this article, the feminist and postcolonial frameworks of distributed reproduction and frontstaging a chemical are used to further explore the concept of global fertility chains. In particular, these approaches are used to trace reproductive bioeconomies that are traveling at the molecular and physiological levels and that link the chemical compound methyl isocyanate (MIC) involved in the 1984 Bhopal gas tragedy to the recent growth of reproductive technologies and surrogacy services in the very same city of Bhopal. The goal of this paper is to identify and contextualize the vertical and horizontal transmission of MIC-mediated chemical toxicity through different generations of human and nonhuman actors, and to understand how this toxicity connects to reproductive bioeconomies as we continue to map out global fertility chains and give particular importance to matters of place, scale, and biological borders. Distributed reproduction allows us to rethink the scope of reproduction and make legible the colonial infrastructures that support the molecular and physiological transmission of toxicities. Frontstaging the chemical MIC allows us to trace the specific pathways of colonial legacies that have assumed unfettered access to raw materials and biolabor extracted from the soil, plants, animals, and humans in Bhopal. The paper explores the role that the chemical MIC plays as a catalyst for the transplacental migration of biopolitics—thereby contributing to an extended appreciation of global fertility chains at new molecular and physiological scales.
Queer Synthetic Curriculum for the Chthulucene: Common Worlding Waste Pedagogies
Authors: Pacini-Ketchabaw Veronica , MacAlpine Kelly-Ann
Published: April 2022

This paper sketches aspects of common worlding waste pedagogies through Donna Haraway’s figure of the Chthulucene. More specifically, it narrates the making and happenings of what we call a queer synthetic curriculum in an early childhood centre. Drawing attention to plastic in order to reframe children’s relationship to it, the article engages with three main questions: How might we refashion waste practices from children’s ubiquitous plastic relations? How might we speculate on the kinds of response-able worlds that might be remade through new kinds of interactions between child and plastic bodies? What might the Chthulucene synthetic futures of early education entail? The queer synthetic curriculum also experiments with creative strategies to learn to live with plastic toxicities without necessarily celebrating them; it embraces the mixed affects that plastic affords (its sensorial pleasures and possibilities as well as the guilt embedded in their toxicity); it plays with the provocative idea that we can no longer separate our fleshy human bodies from synthetic polymer bodies; and it treats plastic as chthonic queer matter. We argue that, by staying with the trouble these risky attachments bring, conditions for futures other than those already determined by synthetic, toxic petrocapitalist modernity and coloniality might emerge in early childhood education.
Storytelling como prática pedagógica: experiência de um curso de formação para professores do ensino fundamental
Authors: Chiodi Marteli Raiane Paula , Pivetta da Silva Monalisa , Alberti Giaretta Jessica
Published: April 2022

Este artigo apresenta resultados de um curso de formação para professores da rede municipal de Coronel Freitas, Santa Catarina. O curso ocorreu de forma remota em virtude da pandemia do SARS-Cov-2, no mês de novembro de 2020. A referida experiência ressaltou a importância da formação continuada de professores da rede básica de ensino, no que se trata de práticas inovadoras e o uso de recursos tecnológicos. Além disso, principalmente em função dos desafios impostos pela pandemia, a experiência evidenciou as dificuldades e a importância de se trabalhar com equipamentos tecnológicos adequados que permitam ao professor desenvolver um trabalho com qualidade e tranquilidade. Para isso são necessários investimentos que garantam a valorização dos professores e a infraestrutura adequada nas escolas.
Acessibilidade no ensino superior na modalidade remota para deficientes visuais: comparação entre Brasil e Portugal
Authors: Guedes Denyse , Pisco Almeida Ana Margarida
Published: April 2022

O objetivo deste artigo é discutir a acessibilidade no ensino remoto, devido à pandemia decorrente da Covid-19, de estudantes do ensino superior com deficiência visual, numa análise comparativa entre Brasil e Portugal, através de estudo de caso, apresentando as facilidades e dificuldades encontradas por essa demanda e a possibilidade e necessidades de mediação a ser exercida entre docente e discente e o uso de ferramentas de tecnologia assistiva. A metodologia utilizada foi enquadrada por uma análise comparativa de pesquisa bibliográfica de publicações científicas e documentos que forneceram, para essa discussão, um referencial teórico, bem como entrevistas semiestruturadas a dois discentes com deficiência visual e dois docentes videntes de cada país. Foi identificado que a modalidade remota de ensino, complexa e desafiadora, urge adequar-se às necessidades dos discentes com deficiência visual e que precisam ser providenciados recursos adequados para a devida inclusão e o devido preparo para uso dos recursos da tecnologia assistiva através das ferramentas utilizadas. Conclui-se que a mudança repentina apresentou desvantagens, como a dificuldade dos docentes para apresentar o material via web, e vantagens, como maior disponibilidade de acesso às informações para o devido acompanhamento dos estudos.
Phytochemical and In-Silico Evaluation of the Pharmaceutically Important Biomolecules Present in Leaf and Seed Extracts of Mucuna pruriens.
Authors:   1Biotechnology Research and Development Center, National Root Crops Research Institute, Umudike, P.M.B 7006 UmuahiaAbia State, Nigeria., J I Reuben-kalu , R Renuka ,   2Department of Biotechnology, Agricultural College and Research Institute, Tamil Nadu Agricultural University, Madurai-625 104, Tamil Nadu,India., D Uma ,   3Department of Biochemistry, Center for Plant Molecular Biology and Biotechnology, Tamil Nadu Agricultural University, Coimbatore- 641003, India, R Gnanam ,   4Department of Bioinformatics, Center for Plant Molecular Biology and Biotechnology, Tamil Nadu Agricultural University, Coimbatore- 641003, India, P Santhanakrishnan ,   Department of Biotechnology, Agricultural College and Research Institute, Tamil Nadu Agricultural University, Coimbatore- 641003, Tamil Nadu, India, E A Alum ,   6Plant Protection General Laboratory & Services, National Root Crops Research Institute, Umudike, P.M.B 7006 Umuahia Abia State, Nigeria.
Published: April 2022

The present research aimed to identify the bioactive compounds present in two varieties of Mucuna pruriens var utilis (IIHR Selection 3 and Arka Dhanvantari) and their pharmaceutical importance evaluated through phytochemical and in-silico screening. The phytochemical screening of the leaf and seed extracts revealed the presence of alkaloids, tannins, flavonoids, phenols, proteins, terpenoids, glycosides, steroids, saponins etc. A total of 43 compounds were identified in the gas chromatography and mass spectrometry (GC-MS) analysis, and the identified biological active compounds were used for in-silico analysis. In-silico docking study revealed potent inhibition of the selected compounds: alpha-D-glucopyranoside, ethyl iso-allocholate and sitosterol against uncoupling protein 2 receptor (UCP2) involved in type 2 diabetes, showing that the binding profiles towards key amino acid residues in the active site were similar to that of the commercial alpha-amylase inhibitors: voglibose, acarbose and glibenclamide. Furthermore, the potent inhibition of another selected compound: 3-(4-hydroxyphenyl) propanoic acid against DJ-1 receptor (PARK7) involved in Parkinson’s disease was determined by docking and it was observed that the binding profile towards key amino acid residues in the active site was similar to that of commercial levodopa. Therefore, M. Pruriens extracts can be explored in managing type-2 diabetes and Parkinson’s disease
Pseudomonas Species in Soil as a Natural Resource for Plant Growth Promotion and Biocontrol Characteristics - An Overview
Authors:   1Department of Microbiology, Nrupathunga University, Nrupathunga Road, Bengaluru 560001, India, N Anuroopa , RAM Anshu B ,   2Department of Biotechnology, Nrupathunga University, Nrupathunga Road, Bengaluru 560001, India, P Ranadev ,   3Centre for Natural Biological Resources and Community Development, 41 RBI Colony, Anand Nagar, Bengaluru 560024, India, DJ Bagyaraj ,   3Centre for Natural Biological Resources and Community Development, 41 RBI Colony, Anand Nagar, Bengaluru 560024, India, R Ashwin ,   3Centre for Natural Biological Resources and Community Development, 41 RBI Colony, Anand Nagar, Bengaluru 560024, India
Published: April 2022

Plant growth-promoting Pseudomonads regulate plant growth by several direct and indirect mechanisms; direct mechanisms include producing phytohormones, increasing nutrient availability and indirect mechanisms include suppressing soil-borne plant pathogens by the production of siderophores, antibiotics, inducing systemic resistance and competing with pathogens. Pseudomonas spp. in soil has been reported from diverse ecological niches and has been well-documented as a model organism for regulating plant growth promotion. These bacteria are endowed with tremendous genetic and metabolic diversity and serve multiple ecological functions in the soil ecosystem. This versatile genus is one of the most commercially exploited bacteria in agriculture. The potential of the different species of Pseudomonas has not been realized sufficiently and requires emphasis on sustainable agriculture for the benefit of humankind. Research in the past decade has revealed that several species of Pseudomonas other than the common species such as P. fluorescens, P. putida, P. aeruginosa, have both plant growth promotion and biocontrol characteristics and have not been commercially exploited. According to the recent List of Prokaryotic names with Standing in Nomenclature (LPSN) there are 507 species of Pseudomonas and the present literature review brings out that 7.29% of them posses plant growth promotion (PGP) and biocontrol traits and thus can be utilized as biofertilizers in the field of agriculture. The role of different Pseudomonas spp. in the supply of plant nutrients and biocontrol of soilborne plant pathogens are covered in this review.
Fibromuscular dysplasia and aortic dissection
Authors: Antonio M Puppo , Manuel Fernández Caro , Sara Martín Sastre , Francisco T Gómez , Jose Mariá López Sánchez
Published: April 2022

Fibromuscular dysplasia is a rare, non-atherosclerotic, non-inflammatory vascular disease that typically affects women between the ages of 20 and 60 years. Although any artery can be affected fibromuscular dysplasia most commonly affects the renal and carotid arteries. Fibromuscular dysplasia of the renal arteries usually presents with hypertension, while carotid or vertebral artery disease causes transient ischemic attacks, strokes, or dissection. Aortic dissection is rare. We present the clinical case of a patient with fibromuscular dysplasia with type B aortic dissection.
Effects of Locations of Spur Dyke on Bed and Scour around Bridge Piers in Meandering Channel
Authors: Athar Mohammad , Naz Farha , Atahr Humaira
Published: April 2022

Spur dykes are the structures which are used to protect the eroding bank of rivers. They are sometimes also used to safeguard the life of many structures such as bridge piers, abutments etc. The efficiency of spur dykes has been checked in straight channels by conducting model tests in laboratories by many investigators. Very few studies were done in curved channels. In present work an attempt has been made to study the effect of location of spur dyke on bed and scour around bridge pier in curved open channel (bend angle = 80o ) with time. Experiment has been carried out in 80o channel bend at constant discharge (3.5×10–3 m3 /s) and bridge pier is located at angular displacement ϴ = 60o . Here ϴ is the angle the line drawn at the inlet of any bend to the line joining the centre of curvature and any point on the outer portion of the bend. It is found that maximum scouring occurs at ϴ = 0o and 20o along inner wall and at ϴ = 60o and 80o along outer wall. It is also found that scouring around bridge pier is more in the vicinity of pier and decreases with increase in distance from pier. The most suitable location for spur dyke to protect bridge pier is at angular displacement ϴ = 20o . Scour developed rapidly during initial time and then rate of scouring decreases with elapse of time.
Study on diel variation and effect of anthropogenic activities on birds
Authors: Priya Gaur  , Praveer Pandey  , Pramila Kori  , Santosh Gaherwal
Published: April 2022

Background: It has been claimed that the turndown of insect population due to strengthening agriculture may have led to a reduction in the number of farmland birds some autecological studies support this postulate. Insect abundance is significantly associated with bird density measures large scale invertebrate sampling was done using suction traps and results showed that with time as food quality and quantity changes there is a decline in farmland birds. Method: The study was conducted for a period of one year, point count method was adopted to record these parameters. Relevant field guides were used to identify observed bird and insect species. Several avian species were seen preying on several insects. Such instances were listed and we also concluded about the insectivorous nature of several avian species based on sightings. Results: In all the four sites collectively, order Lepidoptera of Insect fauna is dominant in all the four study sites. Several anthropogenic stresses were reported in the present study, these activities should be checked regularly and must be prohibited. During three time slots, the activity of birds was recorded and family wise bird activity were observed. Results showed that there were few species common in all the three-time slots and some disparity was recorded in their availability in the morning, noon, and evening respectively.
A review on tin dioxide gas sensor: The role of the metal oxide doping, nanoparticles, and operating temperatures
Authors: Jamal Malallah Rzaij  , Sameer Obaid Nawaf  , Ahmed Khalil Ibrahim
Published: April 2022

Metal oxide gas sensors have many advantages over other solid-state gas monitoring devices, including low cost, ease of manufacture, and small design. However, the shape and structure of sensing materials have a considerable impact on the performance of such sensors, posing a significant challenge for gas sensing properties on materials or dense films to attain high-sensitivity characteristics. Various tin dioxide (SnO2) nanostructures have been devised to increase gas sensing characteristics such as sensitivity, selectivity, and response time, among other characteristics. An overview of the most well-known techniques for synthesizing gas-sensing films, as well as the influence of doping with various metal oxides, nanoparticle size, and operating temperature on the gas-sensing properties of such films, is discussed in this work. The gas sensing mechanisms and the gas detection techniques are presented in detail. The metal oxide doped SnO2 showed a strong response for SO2 and NO2 gases, whereas nanoparticle doping plays a crucial effect in increasing SnO2 sensitivity towards H2, H2S, NO2, CO, Ethanol, etc. Furthermore, the effect of operating temperature on SnO2 response is discussed in this report. SnO2 has a high sensitivity over a wide temperature range (100-350 °C).
Framing the Psycho-Social and Cultural Aspects of Human-Machine Communication
Authors: Fortunati Leopoldina , Edwards Autumn
Published: April 2022

In this introduction to the fourth volume of the journal Human-Machine Communication, we present and discuss the nine articles selected for inclusion. In this essay, we aim to frame some crucial psychological, sociological, and cultural aspects of this field of research. In particular, we situate the current scholarship from a historical perspective by (a) discussing humanity’s long walk with hybridity and otherness, at both the cultural and individual development levels, (b) considering how the organization of capital, labor, and gender relations serve as fundamental context for understanding HMC in the present day, and (c) contextualizing the development of the HMC field in light of seismic, contemporary shifts in society and the social sciences. We call on the community of researchers, students, and practitioners to ask the big questions, to ground research and theory in the past as well as the real and unfolding lifeworld of human-machine communication (including what HMC may become), and to claim a seat at the table during the earliest phases in design, testing, implementation, law and policy, and ethics to intervene for social good.
The Symptom of Ethics; Rethinking Ethics in the Face of the Machine
Authors: Gunkel David
Published: April 2022

This essay argues that it is the machine that constitutes the symptom of ethics— “symptom” understood as that excluded “part that has no part” in the system of moral consideration. Ethics, which has been historically organized around a human or at least biological subject, needs the machine to define the proper limits of the moral community even if it simultaneously excludes such mechanisms from any serious claim on moral consideration. The argument will proceed in five steps or movements. The first part will define and characterize “the symptom” as it has been operationalized in the work of Slovenian philosopher Slavoj Žižek. Although Žižek appropriates this term from Jacques Lacan, he develops the concept in a unique way that exceeds Lacan’s initial psychoanalytic formulations. The second and third parts will demonstrate how the machine constitutes the symptom of moral philosophy, showing how and why it comprises the always already excluded element necessary to define the proper limits of moral subjectivity. The fourth part will then consider two alternatives that promise, but ultimately fail, to accommodate this symptom. And the final section will draw out the consequences of this analysis for ethics and its excluded others.
Sex With Robots and Human-Machine Sexualities: Encounters Between Human-Machine Communication and Sexuality Studies
Authors: Dehnert Marco
Published: April 2022

Sex robots are a controversial topic. Understood as artificial-intelligence enhanced humanoid robots designed for use in partnered and solo sex, sex robots offer ample opportunities for theorizing from a Human-Machine Communication (HMC) perspective. This comparative literature review conjoins the seemingly disconnected literatures of HMC and sexuality studies (SeS) to explore questions surrounding intimacy, love, desire, sex, and sexuality among humans and machines. In particular, I argue for understanding human-machine sexualities as communicative sexuotechnical-assemblages, extending previous efforts in both HMC and SeS for more-than-human, ecological, and more fluid approaches to humans and machines, as well as to sex and sexuality. This essay continues and expands the critical turn in HMC by engaging in an interdisciplinary exercise with theoretical, design, and use/effect implications in the context of sex robots.
I Get by With a Little Help From My Bots: Implications of Machine Agents in the Context of Social Support
Authors: Beattie Austin , High Andrew
Published: April 2022

In this manuscript we discuss the increasing use of machine agents as potential sources of support for humans. Continued examination of the use of machine agents, particularly chatbots (or “bots”) for support is crucial as more supportive interactions occur with these technologies. Building off extant research on supportive communication, this manuscript reviews research that has implications for bots as support providers. At the culmination of the literature review, several propositions regarding how factors of technological efficacy, problem severity, perceived stigma, and humanness affect the process of support are proposed. By reviewing relevant studies, we integrate research on human-machine and supportive communication to organize, extend, and provide a foundation for the growing body of work on machine agents for support.
Embracing AI-Based Education: Perceived Social Presence of Human Teachers and Expectations About Machine Teachers in Online Education
Authors: Kim Jihyun , Merrill Kelly , Xu Kun , Sellnow Deanna
Published: April 2022

Technological advancements in education have turned the idea of machines as teachers into a reality. To better understand this phenomenon, the present study explores how college students develop expectations (or anticipations) about a machine teacher, particularly an AI teaching assistant. Specifically, the study examines whether students’ previous experiences with online courses taught by a human teacher would influence their expectations about AI teaching assistants in future online courses. An online survey was conducted to collect data from college students in the United States. Findings indicate that positively experienced social presence of a human teacher helps develop positive expectations about an AI teaching assistant. The study provides meaningful implications and contributions to our understanding of a machine agent in education
Simulasi Numerik Kelajuan dan Periode Orbit Satelit Mengelilingi Bumi
Authors: Noor Iman , Fitrian Andry , Jahrudin Ahmad
Published: April 2022

Numerical simulation of the satellites’s orbital velocity and orbital period on the earth has been performed. This research aimed to study satellites’s orbital velocity and orbital period on the earthbased on position function. Velocity equation has been gotten from modification equation of centripetal force and equation of earth’s gravitational force. Through numerical calculation of orbital velocityand orbital period equation by function discretization, we got that the velocity and period of satellite at height of 30000 km above the earth’s surface are 3.31 km/s and 19.18 hours, respectively.