bluuebunny/crossref_metadata_2025 huggingface dataset:
Enhanced Recovery Pathway in Open and Minimally Invasive Colorectal Cancer Surgery: A Prospective study on Feasibility, Compliance and Outcomes
Authors: Thomas Martin , Agarwal Vandana , DeSouza Ashwin , Joshi Riddhi , Mali Minal , Panhale Karuna , Salvi Omkar K. , Ambulkar Reshma , Shrikhande Shailesh , Saklani Avnish
Published: November 2022

Background
Enhanced recovery program (ERP) has demonstrated improved postoperative outcomes with increased adherence to pathway. However, there is scarce data on feasibility and safety in resource limited setting. The objective was to assess compliance with ERP and its impact on postoperative outcomes and return to intended oncological treatment (RIOT).
Methods
A single center prospective observational audit was conducted from 2014–2019, in elective colorectal cancer surgery. Before implementation, multi-disciplinary team was educated regarding ERP. Adherence to ERP protocol and its elements was recorded. Impact of quantum of adherence (≥ 80% vs. <80%) to ERP on postoperative morbidity, mortality, readmission, stay, re-exploration, functional GI recovery, surgical-specific complications, and RIOT was evaluated for open and minimal invasive surgery (MIS).
Results
During study, 937 patients underwent elective colorectal cancer surgery. Overall Compliance with ERP was 73.3%. More than 80% compliance was observed in 332 (35.4%) patients in the entire cohort. Patients with < 80% compliance had significantly higher overall, minor and surgery-specific complications, longer postoperative stay, delayed functional GI recovery for both Open and MIS procedures. RIOT was observed in 96.5% patients. Duration to RIOT significantly was shorter following Open surgery with ≥ 80% compliance. Poor adherence to ERP was identified as one of the independent predictors for developing postoperative complications.
Conclusion
The study demonstrates beneficial impact on postoperative outcomes with increased adherence to ERP following open and minimally invasive surgery for colorectal cancer. Within a resource limited setting, ERP was found to feasible, safe, and effective in both open and minimally invasive colorectal cancer surgery.
Study of markovian queueing model with F-policy, impatience customers, feedback and re-service, server vacation and breakdown
Authors: Mahla Nitin , Sharma Dinesh C.
Published: November 2022

A system with two heterogeneous servers with impatient customers and finite capacity is considered. The admission control of customers is based on F-policy. This paper is based on M/M/2 queues, and presents the study of two heterogeneous servers where one server is the primary server and other is secondary. Customers are primarily served by the main server, who also takes customer's feedback into account. If customers are unsatisfied and opt for further service, the second server will serve them. The main server considered is unreliable, that is, it may breakdown at any time. The main server will go for vacation whenever there is no customer to serve. To analyze the performance of the model, we calculated the measures of performance and did the cost analysis. Impact of F-policy on system's estimated profit is shown. At last, conclusions are drawn.
Optimal allocation of water resources in Guyuan City based on improved NSGA-III algorithm
Authors: ZHU Sifeng , Shi Bing
Published: November 2022

At present, there are many ways to solve the problem of water shortage through rational use of water resources, but there are few ways to use artificial intelligence algorithm to solve the optimal allocation of water resources with various needs. In order to alleviate the problem of water resources shortage and unequal distribution in time and space in Guyuan City, this paper firstly analyzes the basic situation of water resources in Guyuan City, and constructs a multi-objective optimal allocation model of water resources with economic benefits, social benefits and ecological benefits as the objectives. Then, NSGA-III algorithm is proposed to solve the optimal allocation scheme of water resources. Based on the original NSGA-III algorithm, multi-point crossover operator and multi-point mutation operator, namely RNSGA-III, are used. In the selection of the next generation, SAW and MCDM schemes were used to evaluate the chromosomes and set the weights to achieve better and more ideal results. Finally, the proposed scheme is compared with the existing configuration scheme based on NSGA-III and NSGA-II algorithms. Simulation experiments show that the proposed scheme is better than the allocation scheme based on NSGA-III algorithm and NSGA-II algorithm in the comprehensive cost of economic benefits, water shortage and ecological benefits, which can provide a basis for the rational allocation of water resources in Guyuan City.
HSSA: A Novel Hybrid Shard Selection Algorithm for performance enhancement of distributed processing system
Authors: D praveen , Totad S G
Published: November 2022

Distributed processing systems are widely used for query search operations , Where the large-size data is partitioned into different numbers of nodes for parallel processing and replication operations. In an exhaustive search approach, for a given query, all the data nodes or shards are searched to find relevant documents matching the user query. Using the sharding technique, we search selected shards to retrieve relevant data for the given query. The conventional shard selection algorithm has significant challenges: Shard ranking Shard cutoff estimation, high latency, less throughput, and high cost in processing extensive size data. Among them are CORI, ReDDe, RankS , and SHiRE are the most popular ones. The limitations of these algorithms are that the performance tends to decrease with the increasing data size, affecting search efficiency and effectiveness. To overcome these challenges, we propose a novel hybrid shard selection algorithm (HSS) to enhance search effectiveness and efficiency. The proposed HSS algorithm is designed and tested with medium and large-size datasets (Gov2, clueweb 9) considering precision, recall, and MAP performance metrics. Considering average throughput, the HSS algorithm performs 21%, 16%, and 12% better compared to CORI, Ranks , and SHiRE algorithms. Similarly, in terms of average latency, the HSS algorithm performs 14.2%, 9.4%, and 8.2% better compared to CORI, RankS , and SHiRE algorithms.
In silico analysis of the profilaggrin sequence indicates alterations in the stability, degradation route, and intracellular protein fate in filaggrin null mutation carriers
Authors: Paul Argho A. , Szulc Natalia , Kobiela Adrian , Brown Sara J. , Pokrzywa Wojciech , Gutowska-Owsiak Danuta
Published: November 2022

Background Loss of function mutation inFLGis the major genetic risk factor for atopic dermatitis (AD) and other allergic manifestations. Presently, little is known about the cellular turnover and stability of profilaggrin, the protein encoded byFLG. Since ubiquitination directly regulates the cellular fate of numerous proteins, their degradation and trafficking, this process could influence the concentration of filaggrin in the skin. Objective To determine the elements mediating the interaction of profilaggrin with the ubiquitin-proteasome system (i.e., degron motifs and ubiquitination sites), the features responsible for its stability, and the effect of nonsense and frameshift mutations on profilaggrin turnover. Methods The effect of proteasome inhibition on the expression of profilaggrin and processed products was assessed by immunoblotting. Wild-type profilaggrin sequence and its mutated variants were analysedin silicousing the DEGRONOPEDIA and Clustal Omega tool. Results Proteasome inhibition stabilizes profilaggrin and its high molecular weight derivatives.In silicoanalysis of the sequence determined that profilaggrin contains 18 known degron motifs as well as multiple canonical and non-canonical ubiquitination-prone residues.FLGmutations generate products with increased stability scores, altered usage of the ubiquitination marks, and the frequent appearance of novel degrons, including those promoting C-terminus-mediated degradation routes. Conclusions The proteasome is involved in the turnover of profilaggrin, which contains multiple degrons and ubiquitination-prone residues.FLGmutations alter those key elements, affecting the degradation routes and the mutated products’ stability.
A Systematic Literature Review: Choice Bracketing in Decision making
Authors: Qandeel Mahmoud Salameh
Published: November 2022

Objectives

In this research, the author revised the most controversial cited articles, which have 100 citations and above, between 1994 and 2022 to investigate the main reasons behind narrow bracketing, and understand if it is rational psychological behavior or biased. Knowing the result would give room for scholars to tackle this issue and look for more enhancements.

Methods

All open-access and not restricted articles through the university of Pécs website were included, as downloadable handbooks as well, but books were excluded. Due to time limitations and grasping pure results, the articles with 100 citations and above, between 1994 and 2022 were selected.

Results

Thoroughly investigating into literature, the author found that scholars discussed “choice bracketing from their niche corner of science and let the other factors behind their research. To name but a few, accepting or rejecting the lottery, and decision differences between two separate choices, or a binary of choices, are not just caused because of determining factors such as bracketing or motivation alone. And it is not necessarily biased.

Conclusions

the author has elaborated and drawn maps for most factors that intervene in decision-making. However, by collecting the most debatable opinions from the literature, it was found that people’s decisions are driven by maximizing utility and loss aversion regarding wealth and income, individual psychology (emotions, heuristics, mental accounting), limitation of rationality and uncertainty, preferences and motivation, and diversification limit and time allocation. But, this is a psychological way of thinking limited to stimuli, time, and rules factors.
JEL Code: A14, D1, D71, D81, D83.
Asenkron Motorlar İçin Endüstriyel Nesnelerin İnterneti Tabanlı Sensör Kartı Uygulaması
Authors: MAMUR Hayati , İZ Atanur , ŞİMŞEK Haydar , ÇIRA Ferhat
Published: November 2022

Bu çalışmada, endüstride yaygın bir şekilde kullanılan ve bu nedenle kestirimci bakım tedbirlerinin alınması önem arz eden asenkron motorlarda (ASM) meydana gelebilecek arızaların ön kestirimlerinin yapılması için endüstriyel nesnelerin interneti (IIoT) tabanlı bir sensör kartı sistemi gerçekleştirilmiştir. Gerçekleştirilen sistem 3 fazlı 250 kW gücünde ve 315L gövde yapısındaki bir ASM üzerinde denenmiştir. Bu ASM’un bulunduğu şartlar geliştirilen gömülü sistemde bulunan sensörlerle algılanmış, gömülü sistem ile bir bulut ağına aktarılmıştır. Sensör kartı uygulamasında Wi-Fi ve Bluetooth haberleşme protokollerini içeren ESP-WROOM-32 mikrodenetleyicisi, frekansa bağlı oluşan titreşim verilerini üç eksende tespit eden bir LIS3DH ivmeölçer ve sıcaklık verileri için 10 KΩ değerinde NTC ASM’un üzerine montajlanmıştır. Bu sensör verileri değerlendirilerek ASM’da oluşabilecek kestirimci bakım tespitleri yapılmış ve ASM için bu tespitler ile kullanıcılara uyarı gönderecek kestirimci bakım kararları oluşturulmuştur.
Saf ve Cam Elyaf Katkılı PEEK Polimerin Sürtünme ve Aşınma Performanslarına Yük ve Kayma Hızının Etkisi
Authors: MASLAVİ Ahmet , ÜNAL Hüseyin , KAŞTAN Alim
Published: November 2022

Endüstrinin değişik sektörlerinde kullanılan makinaların bazı aksamlarında plastik esaslı burç ve yataklar kullanılmaktadır. Yüksek sıcaklık, korozyon, kimyasal direnç ve aşınma direnci istenen uygulamalarda doğru malzeme seçimi, makina elemanının çalışma ömrü açısından oldukça önemlidir. Bu çalışmada, saf poli-eter-eter-keton (PEEK) polimeri ile ağırlık olarak %30 oranında cam elyaf (CE) takviyeli poli-eter-eter-keton (PEEK-30CE) kompozitin tribolojik performansları araştırılmıştır. Deneylerde kullanılan malzemeler, ekstrüzyon yöntemiyle endüstriyel amacıyla üretilmiş çubuk formunda malzemelerdir. Tribolojik deneyler disk üzerinde pim cihazı kullanılarak oda sıcaklığında 2000 m kuru kayma şartlarında gerçekleştirilmiştir. Deneylerde iki farklı yük (30 N ve 60 N) ve dört farklı hız (1, 2, 3 ve 4 m s-1) kullanılmıştır. Deneyler sonucunda saf PEEK polimer ve %30 oranında cam elyaf takviyeli PEEK kompozitinin sürtünme katsayısı, pim sıcaklığı ve spesifik aşınma oranı belirlenmiştir. Deneyler sonucunda kayma hızının artması ile hem saf PEEK hem de cam elyaf takviyeli PEEK kompozitin aşınma oranı artarken sürtünme katsayısı değerleri ise azalmıştır. Düşük yük (30 N) ve hızda (1 m s-1) PEEK kompoziti saf PEEK polimerine göre 2.46 kez daha aşınma dirençli olduğu tespit edilmiştir. Ayrıca optik mikroskop kullanılarak deney malzemelerinin aşınma yüzeyi mikroyapı incelemeleri gerçekleştirilmiştir. Her iki deney malzemesi için düşük yük ve hızlarda adhezif aşınma, yüksek hız ve yüklerde ise abrazif aşınma mekanizması gözlenmiştir.
A review of adsorption techniques for removal of phosphates from wastewater
Authors: Usman Mariam Onize , Aturagaba Godwin , Ntale Muhammad , Nyakairu George William
Published: November 2022

Phosphate is considered the main cause of eutrophication and has received considerable attention recently. Several methods have been used for removal of phosphates in water and these include biological treatment, membrane filtration processes, chemical precipitation, and adsorption. Adsorption technology is highly effective in the removal of phosphate from wastewater even at low phosphate concentrations. Nanomaterials/nanoparticles, carbon-based materials (activated carbon and biochar), and their composites have been widely employed for the adsorptive removal and recovery of phosphate from wastewater due to their exceptional properties such as high surface area and high phosphate adsorption properties. This article is a review of the recently reported literature in the field of nanotechnology and activated carbon for the adsorption of phosphate from wastewater. Highlights of the adsorption mechanisms, adsorption behaviour, experimental parameters, effects of co-existing ions, and adsorbent modifications are also discussed.
Fighting Airborne Spread of COVID-19: An Innovative, Economical and Effective High Vacuum Extra Oral Dental Suction System (HVEDS) for Dental Practices
Authors: Hosein Mervyn , Hanif Ayesha , Baloch Haroon Rashid , Quraeshi Saima
Published: November 2022

Introduction:

The COVID-19 pandemic has led to a great deal of commentary about the airborne spread of the disease. It is of special concern for dentists as most dental procedures generate a significant amount of aerosols and droplets. Given such high risk and inevitable aerosol production in dentistry, special precautions and protective measures to ensure the safe delivery of dental treatment are directed. To ensure negligence-free dental practice, in addition to the standard protective procedures and measures, a high vacuum extra oral dental suction system is a mandated dental armamentarium.

Aims and Objectives:

Most commercially available vacuum aspirators are pricey and require special units with which they can work. In a country like Pakistan, where an expensive armamentarium is neither available nor easily affordable, we present an economical yet effective, high volume extra oral dental suction system for the dental offices which does not require a heavy monetary investment.

Equipment:

An in-house alternate to the commercially available extra oral aspirator is introduced here. We devised a make-shift extra oral aerosol aspirator that can be effortlessly assembled with the materials easily available around dental offices.

Result:

When tried in use, the aerosol and spatter were eliminated through the cone-shaped oil key and collected into the collection bin as observed visually. The equipment, due to its high vacuum suction capability, sucks the aerosol and splatter from the working area to the collection cone.

Conclusion:

Post COVID-19, we can expect a lot of changes in the infection control practices and guidelines. The use of extra oral vacuum aspiration along with the conventional protocol has been recommended to protect both the dental staff and the patients as the high vacuum extra oral aspirator may offer a way to reduce the generated aerosol particulate
Comparative Analysis of Methods for Surgical Treatment of Ankyloglossia: A Review Article
Authors: Oganyan Susanna , Khamidova Marina , Davtyan Albert , Diachkova Ekaterina , Blagushina Natalia , Repina Svetlana , Bokareva Svetlana , Morozova Elena
Published: November 2022

Aim:

Ankyloglossia is a congenital oral anomaly characterized by a short frenulum of the tongue, which can cause nutritional, speech, and developmental problems. The limited movement of the tongue may lead to the development of various anomalies of dentition. Thus, the purpose of this work is to compare the existing methods for surgical treatment of ankyloglossia that involve either laser technologies or scalpels.

Methods:

We analyzed literature sources about patients with ankyloglossia treated with various surgical methods, such as the use of a scalpel, diode laser, CO2laser, Er:YAG laser and Nd:YAG laser.

Results:

The results showed that lasers have multiple advantages over the scalpel: bloodless surgery, which provides good visualization of the surgery field; no need for suturing; the reduction of inflammation and pain in the postoperative period due to the bactericidal properties of the laser; minimal or no scar tissue; decreased surgery time.

Conclusion:

Thus, the laser technique is an alternative to conventional surgery, and, considering the upper mentioned benefits, it can be stated that the laser beam is more effective than a scalpel or scissors.
Nurses’ Perceptions Regarding Exposure to COVID-19 Risks, and Impact of COVID-19 Outbreak on their Work and Psychosocial health: A Cross-sectional Study
Authors: Elneblawi Nora H. , Elshatarat Rami A. , Elhefnawy Khadega A. , Ebeid Inas A. , Aljohani Mohammed S. , Alzahrani Naif S. , Almrwani Abdulaziz M. , Saleh Zyad T.
Published: November 2022

Introduction

Coronavirus (COVID) is a large family of RNA viruses that cause illnesses ranging from the common cold to more severe symptoms.

Objectives

Determine nurses’ perceptions in Saudi Arabia regarding their risks, measures and coping mechanisms to prevent COVID-19 infection and transmission, and the significant associated factors for their anxiety.

Methods

This is a correlational cross-sectional study. A conveniencesampling method was used to recruit a total of 345 nurses. A valid and reliable questionnaire was adapted from a previous study and the generalized anxiety disorder-2items (GAD-2) scale was used to collect the data.

Results

The majority of the participants (75.7%)perceived that they were most likely at risk of getting COVID-19.In terms of preventative actions,84.3% said they were avoiding crowded places, 77.4% were adhering to protocols and recommended measures, about 73.0% of participants were taking nutritional supplements and vitamins, practicing exercises, and changing out of work clothes, 54.8% were taking a shower before going home, and 53.9% were temporarily staying away from home in alternative housing to prevent having COVID-19 or transmitting the virus to their relatives. Furthermore, significant association was found between the participants’ anxiety and the male gender (r=0.1, p=0.04), less nursing experience (r=0.41, p=0.02), number of children (r=0.35, p=0.03). Additionally, participants exposed to COVID-19 patients, who didn’t implement the measures and coping mechanisms to prevent COVID-19 were significantly associated with high level of GAD-2.

Conclusion

The majority of nurses perceived that they were at high risk of getting COVID-19, and were concerned that they could easily to transmit COVID-19 to their relatives. As a result, many implemented preventive measures to protect themselves and prevent transmission of COVID-19 to their families and relatives. The continued attendance of health educational programs about COVID-19 as well as the implementation of basic standard precautions is essential to protect health workers and their families.
WITHDRAWN: Evaluation of Morphine, Methadone, Digoxin, and
Dronabinol Poisoning in Shahid Mostafa Khomeini Hospital in Ilam, Iran
Authors: Manouchehri Aliasghar , Saki Kourosh , Bahmani Mahmoud , Zamanian Golnaz , Shokri Samira , Aidy Ali
Published: November 2022

The article has been withdrawn at the request of the authors of the journal “Current Drug Research Reviews”.

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Imaginarios de Urbanización: Permanencias y Alteraciones desde las Leyendas y Modernización de Tijuana, B.C., México
Authors: Ayala-Macías Elvia Guadalupe
Published: November 2022

En el presente artículo, se exponen algunos imaginarios socioespaciales de una ciudad fronteriza mexicana, ante el marcado proceso de crecimiento, uso y transformación que se ha presenciado en su territorio, de manera intensiva, desde el s.XX. Con trabajo empírico se recuperan las prácticas cotidianas para evidenciar cómo se han consolidado identidades sociales urbanas en las que se yuxtaponen contradicciones y enarbolan elementos patrimoniales al margen de los discursos institucionales. Se recuperan aquellos anhelos, miedos, desigualdades y vulnerabilidades que, históricamente, se han utilizado para describir a Tijuana, dejando en evidencia la complejidad de estas representaciones y su papel en la urbanización.
El Instituto Nacional de la Vivienda como Antecedente en la Política de Vivienda del Estado Mexicano 1954-1970
Authors: Rey-Hernández Pilar Adriana
Published: November 2022

El artículo presenta un recorrido por el origen, el devenir y las funciones de la primera institución pública encargada del tema de la vivienda a nivel nacional en México. Se revisarán sus alcances y limitaciones, así como la relación que los potenciales usuarios establecieron con este organismo, durante los años de su vigencia. Se pretende demostrar que el Instituto Nacional de la Vivienda fue un organismo antecedente de la política de vivienda más unificada y de largo plazo que se consolidó durante la segunda mitad del siglo XX.
Programa de compliance em incorporações habitacionais
Authors: Miguel Batista Waleska , Luiz de Almeida Silvio
Published: November 2022

Neste artigo, afirmamos que os empreendimentos imobiliários são concretizados sem estarem em conformidade com as leis e tratados internacionais, visto que o planejamento urbano naturaliza a obtenção de propriedade por compra e venda e não garante o direito à moradia. O acesso aos bens e equipamentos públicos são usufruídos segundo o valor da propriedade adquirida. Importa mais lucratividade e menos a materialização do direito fundamental social à moradia. Nesse sentido, houve a corrupção da cidade, pela ausência de conformidade com as leis. Cabe à Administração Pública fiscalizar os Programas de Compliance e diretrizes das construtoras do mercado imobiliário para exigir destas que a construção da cidade ocorra segundo normas de integridade previstas pelas próprias construtoras.
Precaução, mudanças climáticas e riscos
Authors: Gasparro Sevilha Grego Patricia , Lebbos Favoreto Ricardo
Published: November 2022

A sociedade moderna comporta elevado grau de complexidade em seu funcionamento. As relações sociais ganharam dimensão e variedade jamais vistas. As ações do Homo sapiens têm impactado enormemente a natureza, afetando-lhe o equilíbrio. As mudanças climáticas são um dos sintomas mais evidentes. Em risco está posta não apenas a sobrevivência da espécie humana como a de todo o planeta. A cena atual: as sociedades desenvolvem-se sob riscos e florescem seus avanços às custas da geração de mais riscos. A ausência de precedentes joga contra previsões comensuráveis. Quanto mais se requerem detalhes, maior a dificuldade. O princípio da precaução irrompe nesse quadro. Pretende-se um limitador da ação mesmo quando se carece de certeza sobre implicações da ação. Sua aplicação não é, porém, a problemática. As dinâmicas sociais de sociedades complexas tornam tudo mais complicado. O presente artigo relaciona precaução, mudanças climáticas e riscos no painel da sociedade moderna – uma “de risco”, como desenvolve Ulrich Beck. Aponta para a necessidade de mudanças significativas no modo de pensar caso se pretenda ter na precaução um mediador efetivo da ação.
O apagamento epistêmico da revolução haitiana no ensino de direitos humanos pelas principais universidades brasileiras
Authors: Vitória Paulo Renato , Cruz Moitinho Dourado Adalberto Davi
Published: November 2022

A Revolução Haitiana (1791-1803) forjou o primeiro Estado-nação fundado a partir da superação radical do colonialismo e da escravidão, e foi pioneira em reconhecer a humanidade plena de todos os seres humanos e em garantir direitos sociais para homens, mulheres e crianças, desafiando as hierarquias raciais e de gênero desenhadas pela modernidade/colonialidade eurocêntrica. Este processo histórico de libertação e reconhecimento foi apagado e silenciado pelas narrativas humanistas hegemônicas, construídas pelo pensamento ocidental, que privilegiam o estudo da afirmação histórica dos direitos humanos a partir da Declaração de Independência dos Estado Unidos e da Declaração de Direitos do Homem e do Cidadão, da França, priorizando a experiência específica de emancipação da burguesia metropolitana, condescendente com o colonialismo, a escravidão e a inferiorização das mulheres. Através de uma abordagem metodológica é quali-quantitativa, de procedimento bibliográfico e documental, inicialmente realizamos uma reflexão teórica acerca da concepção de ser humano desenvolvida a partir da experiência histórica haitiana, em contraste com as predominantes no Ocidente, para demonstrar o seu potencial humanista e decolonial. Em seguida, realizamos uma pesquisa documental das ementas da disciplina Direitos Humanos nas vinte universidades brasileiras e duas sergipanas mais bem colocadas no último Ranking Universitário Folha (2019), que comprovou a existência de um apagamento epistêmico (que também é ético e político) deste processo histórico no ensino dos direitos humanos no Brasil.
Conflito na perspectiva de Georg Simmel e a “crimigração”
Authors: Memória de Andrade Aline , Vital da Rocha Maria
Published: November 2022

Trata-se de artigo que objetiva analisar a “crimigração” como expressão atual da xenofobia, através de análise que usa as ideias de Georg Simmel a respeito do conflito (onde se insere a xenofobia como uma de suas espécies) como referencial teórico. A originalidade do trabalho está em usar a teoria sociológica de Simmel e a de Carl Schmitt acerca da construção do inimigo para analisar como a “crimigração” criminaliza o estrangeiro migrante. Recorre-se à análise bibliográfica qualitativa. Inicialmente, mostra como a xenofobia sempre permeou a história da humanidade, enxergando o estrangeiro como um inimigo. Após, investiga a teoria de Simmel sobre o conflito, que ressaltou seu lado positivo e importância sociológica; analisando, em seguida, se a criminalização das migrações pode ser vista sob algum aspecto positivo, como defende Simmel no âmbito teórico ou se, na prática, só possui elementos negativos. Conclui-se que o aspecto positivo que pode ser vislumbrado é o de evitar a conformação das pessoas, fazendo com que elas questionem certas situações e lutem contra elas. Foi o que ocorreu com a Lei de Migração no Brasil, que alterou os paradigmas nacionalistas e xenófobos do já revogado Estatuto dos Estrangeiros.
Forma jurídica, dependência e superexploração da força de trabalho
Authors: Marques da Silva João Victor
Published: November 2022

O presente artigo busca analisar a Reforma Trabalhista de 2017 (Lei 13.467/2017) a partir da articulação entre a forma jurídica e o capitalismo dependente brasileiro, de modo a explicitar o recrudescimento da superexploração da força de trabalho no Brasil. Para tanto, inicialmente, discutiremos a teoria social marxiana para evidenciar os fundamentos sobre os quais se sustentam as referidas categorias analíticas para, em seguida, determinar como tal articulação pode ser útil para a compreensão do modo de regulação social do trabalho no país. Dessa forma, partindo-se do materialismo histórico dialético e de um recorte qualitativo, argumenta-se que a Reforma Trabalhista realça mais intensamente a genética do Direito do Trabalho como experiência histórica no Brasil, nessa quadra neoliberal.
O sentimento de infância no Brasil
Authors: De Lima Marques Santiago Sousa Vanessa
Published: November 2022

O sentimento de infância, como apresentado por Ariès (2016), foi ganhando novos significados no decorrer do tempo e segundo as relações familiares e culturais de cada sociedade. Apesar das limitações, este sentimento se formou no Brasil, partindo do projeto de colonização, e, hoje, adquire a forma de Proteção Integral. Desse modo, o objetivo deste artigo é enfrentar a questão: é possível decolonizar o sentimento de infância? Para tanto, faremos uso de uma metodologia exploratória, através dos procedimentos bibliográfico e documental, a partir de literatura especializada relacionada à decolonização, aos conceitos, à formulação da ideia de criança para o colonizador e para o colonizado, a influência da previsão legal (e constitucional) na compreensão da infância no Brasil de hoje. Procuraremos, assim, compreender que a decolonização do sentimento de infância exige, inicialmente, o reconhecimento de que há limitações no processo mesmo de decolonizar, além de um isolamento, quase completo, da criança do espaço de produção de uma percepção própria do que é ser criança, permanecendo a ideia de que é um adulto em formação e que precisa de um adulto para se expressar e efetivar seus direitos.
Effectiveness of a patient-centred assessment with a solution-focused approach (DIALOG-A) in the routine care of Colombian adolescents suffering from depression and anxiety: A multicentre cluster randomised controlled trial (Preprint)
Authors: Gómez-Restrepo Carlos , Rumbo Jose , Rodriguez Lopez Marta , Ospina-Pinillos Laura , Stanislaus Sureshkumar Diliniya , Priebe Stefan , Bird Victoria
Published: November 2022

UNSTRUCTURED

Background: Colombia is a middle-income country in South America which has historically struggled with high rates of mental health problems, coupled with a scarcity of mental health care. There is growing concern for the mental health of the adolescent population within this region. There is a significant treatment gap for young people, especially those living in the most vulnerable areas. DIALOG+ is a low-cost patient-centred intervention that can potentially improve the delivery of care and quality of life for adolescents with mental health problems. This exploratory randomised controlled trial aims to evaluate the effectiveness, acceptability, and feasibility of an adapted version of the DIALOG+ intervention (DIALOG-A) in the community treatment of Colombian adolescents with depression and anxiety. Methods: Eighteen clinicians and 108 adolescents will be recruited from primary healthcare services located in Bogota and Duitama, Colombia. Clinicians will be randomised in a 2:1 radio to either the intervention (12 clinicians/72 adolescents) or to the control group (6 clinicians/36 adolescents). In the intervention arm, clinicians will use DIALOG-A with adolescents monthly over 6 months. The control arm will continue to receive routine care. Outcomes will be measured at baseline, 6- and 9-months following randomisation. Semi-structured interviews with all clinicians and a subset of adolescents in the intervention arm will be conducted at the end of the intervention period. Quantitative and qualitative analysis of the data will be conducted. Discussion: This is the first study to test an adapted resource-orientated intervention (DIALOG-A) in the treatment of adolescents with depression and anxiety attending primary care services. If the results are positive, DIALOG-A can be implemented in the routine care of adolescents with these mental health problems and provide valuable insight to other middle-income countries.
Trial registration number and date: ISRCTN13980767 (18/03/2022)
Experimental validation and identify the characteristics of chromatin modulator and potential candidate drugs for sepsis (Preprint)
Authors: wang qianfei , Hou Mengxing , zhang weichao , wang chenxi , li xin , tao yulei , liu yuan , mei jianqiang , chen fenqiao
Published: November 2022

BACKGROUND

Sepsis is a common acute and critical disease, which is a systemic inflammatory response syndrome. More and more evidence shows that chromium regulators (CRs) are involved in the progress of inflammation and sepsis.

OBJECTIVE

The purpose of this study was to explore the role of CRS in sepsis patients and provide prognostic value

METHODS

CRs were obtained from previous top level studies. We downloaded four microarrays（GSE11755、GSE12624、GSE28750、GSE48080）from Gene Expression Omnibus (GEO). CRs related genes were extracted for differential analysis, and GO, KEGG, DO analysis was conducted for different CRs. We conduct PPI analysis on different CRs and screen hub genes. We use the ssGSEA algorithm to obtain the relevant immune cells and immune function infiltration matrix, and draw the relevant heat map for correlation analysis and difference analysis between immune cells and immune function. We analyzed the correlation between hub genes, immune cells and immune functions, and screened out the most relevant hub genes (IHGs). Finally, IHGs are used to build models, and nomograms, ROC curves, and calibration charts are drawn to predict IHGs related drugs and related miRNAs and genes, and RT-PCR is used to verify related genes.

RESULTS

We obtained 69 normal blood samples and 106 sepsis patients' blood samples, and extracted relevant CRS genes. GO analysis shows that CRS gene involves histone modification, peptidyl−lysine modification、chromatin remodeling, etc. KEGG analysis involves cell cycle, Viral carcinogenesis and Hepatocellular carcinoma signal pathways. We identified 10 hub genes, including TP53, EZH2, RNF2, and mapped relevant maps. 10 drugs such as PHA may be useful for the treatment of Sepsis. MiRNAs such as hsa-miR-4281, hsa-miR-4715-5p, hsa-miR-409-5p and TP53, CHD3, CBX4 genes are associated with this disease. RT-PCR results showed that the expression levels of TP53 and CHD3 were significantly reduced, and the expression levels of CBX4 were significantly increased

CONCLUSIONS

Our study provides new insights into the role of CRS in sepsis, and provides reliable biomarkers to determine the prognosis of sepsis patients.
Identification of risk indicators for periodontitis: Machine Learning and Feature Importance Analysis (Preprint)
Authors: Park Hee-Jung
Published: November 2022

BACKGROUND

Periodontitis is a multifactorial disease that involves numerous risk factors and indicators. While a few factors, such as age, uncontrolled diabetes, and smoking, have been well established as true risk factors for periodontitis, many risk factors and indicators remain debatable due to conflicting data from previous studies. This calls for a novel approach to data analysis to improve the accuracy of risk assessments and disease predictions.

OBJECTIVE

This study aimed to assess the ability of machine learning approaches to identify important risk indicators for periodontitis using data from the 2015–2018 Korea National Health and Nutrition Examination Survey of 13,946 subjects

METHODS

The severity of periodontitis was categorized as non-severe and severe according to the community periodontal index. Machine learning models such as classification and regression tree, gradient boosting machine, random forest, extareme gradient boost (XGBoost), and multilayer perceptron (MLP) were developed, and their performance based on the area under the receiver operating characteristic curve (AUC) wasXGBoost and MLP showed higher performance than the logistic regression model.

RESULTS

XGBoost and MLP showed higher performance than the logistic regression model. The important risk indicators for periodontitis were age, sex, education, smoking, blood pressure, use of interdental cleaning aids, and glycated hemoglobin. Interestingly, further analysis showed that glycated hemoglobin and frequency of binge drinking were significant indicators of severe periodontitis. While the findings of this study showed moderate AUC in machine learning models, it confirmed consistent risk indicator rank, which was derived from feature importance analysis such as Gini impurity, permutation importance, and Shapley additive explanations.

CONCLUSIONS

Collectively, our findings suggest the importance of considering a novel data analysis methodology, such as machine learning, for the better management of periodontitis.
Participatory Surveillance for COVID-19 Trend Detection in Brazil: Cross-sectional Study (Preprint)
Authors: Wittwer Salome , Paolotti Daniela , Lichand Guilherme , Leal Neto Onicio
Published: November 2022

BACKGROUND

The ongoing COVID-19 pandemic has emphasized the necessity of a well-functioning surveillance system to detect and mitigate disease outbreaks. Traditional surveillance (TS) usually relies on health care providers and generally suffers from reporting lags that prevent immediate response plans. Participatory surveillance (PS), an innovative digital approach whereby individuals voluntarily monitor and report on their own health status via web-based surveys, has emerged in the past decade to complement traditional data collection approaches.

OBJECTIVE

This study compared novel PS data on COVID-19 infection rates across 9 Brazilian cities with official TS data to examine the opportunities and challenges of using PS data, and the potential advantages of combining the 2 approaches.

METHODS

The TS data for Brazil are publicly accessible on GitHub. The PS data were collected through the Brazil Sem Corona platform, a Colab platform. To gather information on an individual’s health status, each participant was asked to fill out a daily questionnaire on symptoms and exposure in the Colab app.

RESULTS

We found that high participation rates are key for PS data to adequately mirror TS infection rates. Where participation was high, we documented a significant trend correlation between lagged PS data and TS infection rates, suggesting that PS data could be used for early detection. In our data, forecasting models integrating both approaches increased accuracy up to 3% relative to a 14-day forecast model based exclusively on TS data. Furthermore, we showed that PS data captured a population that significantly differed from a traditional observation.

CONCLUSIONS

In the traditional system, the new recorded COVID-19 cases per day are aggregated based on positive laboratory-confirmed tests. In contrast, PS data show a significant share of reports categorized as potential COVID-19 cases that are not laboratory confirmed. Quantifying the economic value of PS system implementation remains difficult. However, scarce public funds and persisting constraints to the TS system provide motivation for a PS system, making it an important avenue for future research. The decision to set up a PS system requires careful evaluation of its expected benefits, relative to the costs of setting up platforms and incentivizing engagement to increase both coverage and consistent reporting over time. The ability to compute such economic tradeoffs might be key to have PS become a more integral part of policy toolkits moving forward. These results corroborate previous studies when it comes to the benefits of an integrated and comprehensive surveillance system, and shed light on its limitations and on the need for additional research to improve future implementations of PS platforms.
Nurse-led innovations implemented during COVID-19 for adults living with chronic disease or multimorbidity: A scoping review (Preprint)
Authors: Whitehead Lisa , Van Lochem Colleen , Babutunde-Sowole Olutoyin , George Cobie , Quinn Robyn , Beks Hannah
Published: November 2022

BACKGROUND

The COVID-19 pandemic has redefined healthcare. Nurses, the largest registered health workforce worldwide have responded to meet the demands and changes in health care. Understanding how nurses have innovated practice to respond to COVID-19 will map current evidence.

OBJECTIVE

To scope all available peer-reviewed evidence on nurse-led innovations to support adults living with chronic disease or multimorbidity in response to COVID-19.

METHODS

A comprehensive systematic search strategy was used to query multiple electronic databases from 2020 through to October 2022. After removing 162 duplicates, 751 records were screened and 10 records were included in the review. The Joanna Briggs Institute’s scoping review methodology was used to guide all stages of the review.

RESULTS

The number of nurse-led innovations published to date is small (n=10) relative to the size of the workforce and the observation of rapid changes across healthcare systems as a result of COVID-19. The innovations reported involved the transition of an existing face-to-face intervention to an information communications technology platform. Some evidence was reported on patient satisfaction and acceptability of nurse-led innovations.

CONCLUSIONS

The focus on interventions underpinned by information communication platforms highlights the importance of a digitally competent workforce. Key gaps in the literature were identified including reports by geographical area and across a variety of clinical settings. Few nurse-led innovations have been published. A call for greater visibility of nurse-led innovations during this period of significant change in the field of chronic disease management is made.

CLINICALTRIAL

(https://osf.io/zmep2/).
The Impact of Diversified Income and Agricultural Tax Reform on the Consumption of Chinese Rural Residents
Authors: Zhou Fangyuan , Luo Xiao , Nujoma Kandorera Angela
Published: November 2022

Income from different sources has become an important guarantee to sustain family life and normal expenses in China. How different sources of income affect farmers’ expenditure levels and how they have influenced farmers’ consumption since the agricultural tax reform in China since the 20th century has become a question worth exploring. Panel data from 2016 to 2020 are utilized to examine rural residents’ consumption expenditures and their sources of disposable income by region to analyze the impact of different income sources on farmers’ consumption and the correlation between income before and after agricultural tax reform, and finally conducts an analysis of future scenarios based on a time series model. The research results show that the elasticity of income from different sources on rural households’ per capita consumption expenditure is different, among which wage income is the most elastic, while household business income has a relatively small effect on consumption expenditure, but through data analysis we can find that agricultural tax reform has a significant and continuous promotion effect on rural households’ per capita consumption expenditure. The continuous cycle of agricultural tax reform is long, and the transmission chain through less tax payment, expanded reproduction, harvest, realization, and then consumption is long, thus there is a certain lag in tax reduction effect. Income from such sources in the first three years has a large impact on the current period data, while the first four and five years have a relatively small impact on current business income.
Organizational Models and Dynamic Capabilities: From Bureaucratic Structures to a Freedom and Emotional Management for a Sustainable, Participative and Innovative Bank. The Case of Italian Banks
Authors: Baravelli Maurizio , Pilotti Luciano
Published: November 2022

The thesis that we support in this introductory work, and which we propose for discussion and technical-scientific debate, is that even the online bank, and even better the digital bank, towards which we are moving with ever-increasing acceleration, cannot escape the trends, now widespread in businesses, towards flexible and decentralized models, which recognize the principle of self-organization and empowerment, and therefore towards organizational forms that involve and participate managers and employees. Organizational models that place human capital and the ethical-motivational wellbeing of people (workers and managers) at the centre and that, if involved in decision-making processes, are capable not only of increasing dynamic capabilities but also of innovating them (renewing) by leveraging, above all, the enhancement of middle management. In this work we argue that the characteristics of organizational models promote the dynamic capabilities in a circular approach integrating vertical and horizontal competences in a flattening organization. Freedom and Emotional management shape organizations capable of adapting and regenerating even in rapidly changing environments. Reinforcing this position is the circumstance that Italian banks find themselves having to redesign their business and managerial models not only to make them economically and financially sustainable to counter the current profitability crisis, but also to make them consistent with social (and environmental) sustainability criteria by adapting to the new European regulation. A transformation that push towards the increasing convergence of eco-efficiency and eco-effectiveness with more participating and creative human resources for the resilience.
Un camino de 50 años del SUAyED, UNAM
Authors: Amador Bautista Rocío
Published: November 2022

El presente artículo tiene como objetivo integrar un compendio de la evolución del Sistema Universidad Abierta (sua, 1972-1996) y del Sistema Universidad Abierta y Educación a Distancia (suayed, 1997-2022) de la Universidad Nacional Autónoma de México (unam), durante nueve períodos de rectorados en cinco décadas. En este contexto histórico, se destaca la implantación e implementación de programas de estudio de bachillerato, profesionales, posgrado y educación continua en las modalidades de educación abierta, a distancia y mixta; y la transformación de los procesos de enseñanza y aprendizaje, con el uso de los medios audiovisuales y de comunicación de masas, tecnologías de información y comunicación, y redes y plataformas educativas.
Recordemos lo importante que es la lactancia materna
Authors: Morales López Sara , Colmenares Castaño Mariana , Cruz Licea Verónica , Iñarritu Pérez María del Carmen , Maya Rincón Natalia , Vega Rodríguez Aidee , Velasco Lavín María Rosario
Published: November 2022

Breastfeeding is considered a primary strategy in health promotion and disease prevention. This document addresses aspects that make evident the importance of breastfeeding for the health of the mother and her child, and the role of health professionals to promote, protect and support breastfeeding. An epidemiological panorama of breastfeeding in Mexico is presented, the main constituents of milk, the benefits of breastfeeding, both for the baby and for the mother, the barriers and myths that somehow influence breastfeeding, the main problems of breastfeeding and how to solve them, the proposed steps and the technique to achieve successful breastfeeding and promote a culture of breastfeeding.