bluuebunny/crossref_metadata_2025 huggingface dataset:
Combined use of fractional co2 laser and collagenase diadynamophoresis in correction of contour plastic surgery complications
Authors: Gerasimenko Marina Yu. , Alekseenko Irina P.
Published: September 2021

Background. One of the most frequent complications of aesthetic correction methods is the problem of contouring, visualization, or local tightening of the skin at the sites of administration of the agent based on calcium hydroxyapatite, which occurs in violation of the injection technique.
Aim: to study the efficiency of the combined method including a course of diadynamophoresis of collagenase 1000 KE (collagenase units) and a fractional CO2 laser procedure in correction of a surface-injected preparation in late terms.
Methods. Clinical and instrumental examination of 24 women (average age 38.2 3.5 years) was conducted. All patients complained of complications after the contour plastic surgery procedure using a preparation based on calcium hydroxyapatite, in the form of contouring of the preparation and superficial skin tightening on the face at the filler injection site.
Results. When comparing the control, main and reference groups, it was revealed that the combined use of collalysin diadynamophoresis and fractional CO2 laser at low parameters improves significantly the quality of life in terms of the adapted dermatological index. Clinical improvement was registered in all groups, but it was most significant in the main one, which correlated with the data of ultrasound examination with a 33 MHz sensor. In the main group, faster biodegradation was noted, and the volume of the surface-injected filler decreased 2.5 times after 1 month and 6 times after 2 months.
Conclusion. The combined use of collalysin diadynamophoresis and a fractional CO2 laser is an effective complex for the correction of complications after contour plastic surgery of fillers based on calcium hydroxyapatite.
Observations on the healing effect of erysipelas
Authors: Faerstein S.
Published: September 2021

At the present time, there are already many observations of the health-improving effect of some diseases on others; so, according to the work of Wagner-Jauregg and others, there is an improvement in many cases with progressive paralysis and dorsal tabes after vaccinations of malaria and relapsing fever. Some authors, like Schreber and others, have seen improvement in gonorrhoid patients after malaria vaccination.
Phase-matched filters: Application to the study of Love waves
Authors: Goforth Tom , Herrin Eugene
Published: September 2021

abstract

Seismic surface waves are usually composed of overlapping wave trains representing multipath propagation. A first task in the analysis of such waves is to identify and separate the various component wave trains so that each can be analyzed separately.

Phase-matched filters are a class of linear filters in which the Fourier phase of the filter is made equal to that of a given signal. Herrin and Goforth (1977) described an iterative technique which can be used to find a phase-matched filter for a particular component of a seismic signal. Application of the filters to digital records of Rayleigh waves allowed multiple arrivals to be identified and removed, and allowed recovery of the complex spectrum of the primary wave train along with its apparent group-velocity dispersion curve.

A comparable analysis of Love waves presents additional complications. Love waves are contaminated by both Love and Rayleigh multipathing and by primary off-axis Rayleigh energy. In the case of explosions, there is much less energy generated as Love waves than as Rayleigh waves.

The applicability of phase-matched filtering to Love waves is demonstrated by its use on earthquakes occurring in the Norwegian Sea and near Iceland and on a nuclear explosion in Novaya Zemlya. Despite severe multipathing in two of the three events, the amplitude and phase of each of the primary Love waves were recovered without significant distortion.
Landslides of central Vancouver Island and the 1946 earthquake
Authors: Mathews W. H.
Published: September 2021

abstract

Numerous fresh landslide scars visible in aerial photographs of central Vancouver Island taken in the period 1946 to 1957 are attributed to the earthquake, magnitude 7.2, of June 23, 1946. Distribution of the scars shows a very strong concentration in a zone parallel to the favored fault-plane solution but some 50 km to one side, straddling the favored P nodal auxiliary plane. Topography precludes the development of a corresponding belt of landslides on the opposite side of the favored fault plane. A high proportion of slides face southerly or southwesterly but an explanation for this favored orientation is lacking.
Implications for dance/movement therapy in forensics
Authors:   , Carey Melissa E. , Goodill Sherry W.
Published: September 2021

This literature-based study presents a training module that applies dance/movement therapy (DMT) observation methods as assessment tools in the realm of forensics. Literature on behavioral research, nonverbal communication, the forensic applications of nonverbal communication, movement studies, and the current ethical implications of behavioral science in the courtroom is reviewed. This investigation discusses the current uses and problems presented in using trial consultants and how movement observation techniques may assist in regulating this field. Literature linking behavioral research and DMT assessment is presented for the purpose of understanding how the two domains can be synthesized for the use in the legal field. From this analysis, a theoretical model that applies DMT to behavioral evaluation in the courtroom evolved. This model identifies four categories for the assessment of nonverbal behavior in this setting. The training module illustrates how this application could be taught to law students. Recommendations for future research with the model are provided.
Reconstructing Professional Philosophy: Lessons from Philosophy as a Way of Life During a Time of Crises
Authors: Kramer Eli , Faustino Marta
Published: September 2021

This article reflects on the way the Covid-19 hecatomb has disclosed and unraveled the ongoing crisis of professional philosophy, and suggests some lessons that might be taken from the pandemic, urging academic philosophers to take action regarding the future of their work in philosophy departments and institutions. In the first section of the article, we highlight some lasting criticisms to academic philosophy and explore one particular nasty thorn in the side of philosophers doing the kind of work that might speak to broad audiences facing a crisis of meaning and living: the rush to publish instead of “perishing” without a secure academic position. In the next section, we discuss philosophy as a way of life (PWL) as an alternative nascent field in academic philosophy that, while garnering respect and recognition within the academy, has regained connections with a broader public desperate for ways to chart their own paths of meaningful living, especially when facing a deeply challenged and fractured world. PWL helps address the crises of meaning many in the academy face (both teachers and students) and the absence of rich philosophical reflection and communities in the broader public, which otherwise all too easily fall prey to hucksters, con-artists, and authoritarian and conspiratorial forces. We argue that this kind of wholistic critical development of PWL from the ancient world is designed to enact a prefigurative or eutopian politics. We conclude by situating our recommendations into a broader reconstruction of professional philosophy needed at this critical cultural moment.
Comparison of the anti-nociceptive effect of dexmedetomidine with that of clonidine immediately prior to propofol injection in alleviating propofol injection pain
Authors: Sultana Rehsma , Ali Mohammed Mohsin
Published: September 2021

Background: Propofol is the drug of choice for induction of anaesthesia because of its rapid onset and short duration of action, easy titration, and favourable profile for side effects. But three out of five patients experience pain on injection of propofol.  Alleviation of Propofol injection pain (PIP) is thus a major concern and several interventions have been investigated to alleviate the pain associated with propofol injection. Clonidine was found to alleviate the pain of injected propofol effectively. Dexmedetomidine is also an alpha-2 adrenoceptor agonist but is more selective than clonidine and has analgesic and sedative properties. The aim of the study was to compare the anti-nociceptive effect of dexmedetomidine with that of clonidine immediately prior to propofol injection in alleviating propofol injection pain.Methods: A randomized controlled study was conducted on 60 patients admitted in Malla Reddy Institute of Medical Sciences, undergoing elective surgeries under general anaesthesia (GA) for 2 years from October 2015 to September 2017. The patients were randomly divided into two groups (30 each). Group A was administered intravenous injection clonidine 0.5 µg/kg. Group B was administered intravenous injection dexmedetomidine 0.5 µg/kg.Results: In the present study, difference between the study groups in their mean age, mean weight, gender, ASA grading was not found to be statistically significant. The difference between the groups in incidence of pain on propofol injection was found to be significant statistically. The mean baseline heart rate was declining and mean arterial blood pressure was increasing in both the groups but the difference was not found to be statistically significant.Conclusions: Pre-treatment with 0.5 µg/kg of IV dexmedetomidine is more effective as compared to IV clonidine in alleviating propofol injection pain.
Varied presentation of tuberculosis adenopathy: an immunological and diagnostic contemplation
Authors: Ganesan Natesh , Vidyasagar Sachin , Mani Anbumaran Parivakkam , Vadivelu Gangadharan
Published: September 2021

Tuberculous lymphadenitis is the most common presentation of extra pulmonary tuberculosis EPTB. Clinical and radiological presentation of disease may vary and differential diagnosis includes both benign and malignant conditions such as lymphomas and sarcoidosis. We present two case reports of tuberculous lymphadenitis with varied presentation. In case report Ⅰ, patient had undergone splenectomy due to traumatic splenic rupture had classical symptoms of tuberculosis, chest X-ray, CT thorax showed mediastinal and cervical lymphadenopathy. FNAC showed a picture of granulomatous lesion. In case report ⅠⅠ patient came with complaints of abdominal pain in hypochondriac region. CT and USG abdomen showed multiple enlarged retroperitoneal lymph nodes which led to a provisional diagnosis of lymphoma after which lymph node biopsy showed a granulomatous picture. This case report stresses the importance of early and quick diagnosis of tuberculosis in immunocompromised patients and highlights the risk of misdiagnosis of tuberculous lymphadenitis with other benign and malignant causes of lymphadenopathy and the importance of humoral mediated immunity in tuberculosis.
Brain networks and medical education
Authors: Prineethi Sheena , Bharath Rose Dawn , A. Thamodharan , Mani Sunithi
Published: September 2021

Background: There has been significant progress in understanding the human brain with the development of modalities like functional magnetic resonance imaging (fMRI), positron emission tomography (PET) etc. Education is an important source of intellectual, emotional and cultural stimulus to the brain. In this resting fMRI study, we aim to map out specific regions in the brain in which changes occur relating to memory, language, motor, behavioural and cognitive functions after five years of undergraduate medical education and how this knowledge can bring us closer to understanding the brain and its functions and applications in clinical practice.

Methods: A total number of 48 normal, healthy medical students from our medical college were included in the study, and were divided into two groups, the first group completed five years of under-graduate medical training and the second group consisted of individuals who had only 4 months of exposure to medical training. Resting state fMRI study was performed and seed-to-voxel based functional connectivity analysis method was used to derive between group differences

Results: Out of the 48, 13 played one or more sport professionally, 8 were musically oriented with skills to play one or more musical instrument professionally and 9 had other talents (2-Good academic, 2-theatre, 3-dancing, 2-art like pottery and painting).

Conclusions: There were significant differences in the right inferior temporal gyrus which is the seat of many cognitive functions like language, emotion and memory and the left cerebellar hemisphere, which is known to play a role in fine motor functions, language and visual learning.
Calidad de vida, buen vivir y salud. Indígenas en la ciudad: el caso de 6 pueblos migrantes en Bogotá
Authors:   Universidad El Bosque, Vargas-Cruz Sandra , Parra-García Irene
Published: September 2021

The work addresses the situation of six migrant indigenous peoples who currently reside in the city of Bogotá: Los Pastos, Misak misak, Wounaan, Yanacona, Nasa and Kamëntšá biya. An interdisciplinary team developed the work; due to this, the phenomenon is analysed from dierent approaches, although with a special emphasis on health. It constitutes a reflection on the condition of being indigenous in Latin American cities from the redefinition of identities, through the challenges for the guarantee of rights outside their territories, to the reasons for migration and the characterization of the migrant indigenous’ households in the city. The book includes components of the broad discussion on indigenous studies and the common situations that they may experience when settling in Bogotá, and the importance of making visible the specific experience of each people participating in the study.
Zagrożenia jako główna determinanta bezpieczeństwa międzynarodowego
Authors: Rogozińska Agnieszka
Published: September 2021

The essence of international security concerns the possibility of counteracting threats created by other entities, creating conditions for its stable and harmonious functioning and development, and securing the values and interests of the state. The aim of the article is to identify the definition of international security and to diagnose contemporary threats to international security. The main research problem was formulated in the form of the question: What are the theoretical aspects of contemporary threats to international security? In the research process, the methodology of scientific cognition was used, including mainly the analysis and criticism of literature.
The Unmet Supportive Care Needs of Omani Women Diagnosed with Breast Cancer
Authors: Al-Azri Mohammed , Al-Bimani Khalid , Al-Maqbali Al-Anoud , Al-Riyami Hala , Al-Shabnooti Al-Kuthar , Panchatcharam Sathiya M , Jaju Sanjay
Published: September 2021

Objectives: This study aimed to assess the unmet supportive care needs of Omani women with breast cancer (BC). Methods: This cross-sectional study was conducted from November 2020 to February 2021 among 250 adult Omani women diagnosed with BC at Sultan Qaboos University Hospital, Muscat, Oman. An Arabic version of the 34-item Supportive Care Needs Survey-Short Form tool was used to determine perceived unmet supportive care needs across five domains. Results: A total of 181 women participated in the study (response rate: 72.4%). The domain with the highest mean score per item was health system and information (mean score: 3.33), with the greatest unmet need in this domain being information about what the patient could do to help themselves get well (40.9%). The domain with the second highest mean score per item was patient care and support (mean score: 3.04), with the greatest unmet need being for clinicians to be more sincere with the patient (36.5%). Higher total mean scores were reported by women who had visited the hospital four times or more over the two months preceding the study (P = 0.045), those with stage 3 or 4 cancer (P = 0.047) and those who had recently undergone radiotherapy or chemotherapy (P = 0.014). Conclusion: Most unmet supportive care needs fell under the health system and information domain. Healthcare providers in Oman should explore patient concerns and provide sufficient information at various stages of the care process to decrease the anxiety associated with living with cancer.Keywords: Breast Neoplasms; Needs Assessment; Palliative Supportive Care; Women; Oman.
A histological investigation of dental crown characters used in mosasaur phylogenetic analyses
Authors: Street Hallie , LeBlanc Aaron , Caldwell Michael
Published: September 2021

Mosasaur researchers have used varieties of tooth crown ornamentation as diagnostic and phylogenetic characters for decades. Such tooth crown features include facets, flutes, striations, serrated carinae, and coarse anastomosing texture. This study investigates the relative contribution of dentine and enamel to the development of these dental characters and assesses possible homologies between these structures. Histological analysis of isolated mosasaur teeth revealed that flutes and facets develop initially from the dentine, and the external enamel morphology we observe macroscopically mirrors the shape the underlying dentine. Striations combine underlying contributions from the dentine with additional and irregular enamel deposition that results strictly from amelogenesis. In both serrated carinae and anastomosing texture the border between the dentine and the enamel is smooth, and these external ornamentations form through variations in enamel development. Based on these observations, we infer that flutes and facets are part of a morphological spectrum and should not be treated as separate phylogenetic characters. Conversely, striations develop differently than flutes and facets, and should therefore be treated as a distinct character. We recommend referring to the “serrations” on mosasaur carinae as crenulations to differentiate these enamel-only structures from true denticles possessing a dentine core. Anastomosing texture can also coincide with significant apical thickening, both of which could be adaptations for processing hard-shelled prey. Care must be taken when using tooth crown features as diagnostic or phylogenetic characters because seemingly different morphologies can have similar developmental origins, and tooth morphology can be more closely tied to diet than to common ancestry.
Evaluation of Cyber Victimization and Self-Esteem Level in High School Students
Authors: AYDOĞAN GEDİK Sevil , ÜNSAL Alaettin , ARSLANTAS Didem , ATAY Emrah , ÖZTÜRK EMİRAL Gülsüm
Published: September 2021

Objective: The aim of this study is to determine the prevalence of cyber victimization among high school students, to examine some possibly related variables and to evaluate the relation with level of self-esteem in Sivrihisar district of Eskişehir.

Method: This is a cross-sectional study conducted between May-June 2018. The study group consisted of 712 students. The questionnaire used in the study includes The Revised Cyber Bullying Inventory-II and Rosenberg Self-Esteem Scale. Chi-square test, Mann Whitney U test and Logistic Regression Analysis were performed to analyze the data. It was considered significant if p≤0.05.

Results: The 60.1% of the students were female, and the mean value of ages was 16.3±1.2 in years (ranged 13-20). The prevalence of cyber victimization was 51.3% (n=365). When compared to other groups in same subtitle, the risk of being cyber victim was 1.66 times higher in the 9th and 10th grades (CI: 1.20-2.30), 4.56 times higher in individuals with poor family income (CI: 1.18-17.64), 1.53 times in the middle ones (CI: 1.10-2.16), 3.15 times in individuals with social media accounts (CI: 1.00-9.85), and 2.80 times higher in individuals having problems with anyone on the internet (CI: 1.96-4.02). Rosenberg Self-Esteem Scale scores were higher in cyber victims (p=0.027).

Conclusion: It was concluded that cyber victimization is an important problem among high school students in Sivrihisar, and cyber victimization is observed higher in the group with low self-esteem.
La Asociación Internacional de Gendarmerías y Fuerzas Policiales con Estatuto Militar (FIEP): ¿un instrumento a disposición de la gestión integrada de fronteras europeas?
Authors: Acosta Sánchez Miguel Á.
Published: September 2021

La Asociación Internacional de Gendarmerías y Fuerzas Policiales con Estatuto Militar (FIEP), representa un caso muy particular de cooperación. Esta estructura permite la participación de fuerzas de Estados europeos con otros Estados no europeos y en igualdad de condiciones. Por otra parte, sus objetivos facilitan una acción muy importante en la gestión integrada de fronteras exteriores, incluido el control y vigilancia fronterizos y actuando con Estados de origen y tránsito de la inmigración, y ello a través de mecanismos de formación conjunta e intercambio de información, particularmente. Finalmente, la FIEP representa una interesante herramienta complementaria con otras formas de cooperación policial en el contexto europeo, como Eurogendfor y Frontex.
Recibido: 10 septiembre 2020Aceptado: 21 junio 2021
Experimental investigation of biodiesel-n-butanol fuels blends on performance and emissions in a diesel engine
Authors: Mickevicius Tomas , Labeckas Gvidonas , Slavinskas Stasys
Published: September 2021

The paper presents the experimental test results reflecting the comparative changes in the performance efficiency and emissions of the exhaust of a naturally aspirated, four-stroke, single-cylinder, air-cooled diesel engine due to its transition from neat rapeseed oil biodiesel to fuel blends prepared by mixing in various proportion (by volume) rapeseed methyl ester (B) and butanol (Bu). The lubricity properties of biodiesel-n-butanol fuel blends were studied using HFRR method. In contrast to previous works, the undertaken investigation is performed with a totally renewable, binary liquid biofuel blends. The purpose of the research is to reduce simultaneously the production of NOx emissions and the exhaust smoke with respect to neat biodiesel due to potentially improved homogeneity of combustible mixture and particulate matter emissions benefits suggested by the higher oxygen content (21.62wt%) and the relatively lower carbon-to-hydrogen ratio (4.8) of the normal n-butanol. The tests revealed that the brake specific fuel consumption for the binary biodiesel-n-butanol fuel blends is always higher than that neat biodiesel produces under the same loading conditions. Maximum nitrogen oxide (NOx) emissions were obtained with the engine running on neat biodiesel (2290 ppm). At full (100%) load conditions, the lowest NOx emission was obtained with the engine running on a biofuel BBu20 blend. The lowest level of carbon monoxide emissions (CO) was observed, when engine running with the most butanol-oxygenated biofuel blend BBu20.The highest smoke opacity of the exhaust was obtained when the engine was fuelled with neat biodiesel and at full load.
A kelet-közép-európai országok térségeinek konvergenciaklubjai
Authors: Szakálné Kanó Izabella , Lengyel Imre
Published: September 2021

A tanulmány az EU (Európai Unió) hat KKE-tagállama (kelet-közép-európai), Bulgária, Csehország, Lengyelország, Magyarország, Románia és Szlovákia NUTS 3-as (Nomenclature des Unités Territoriales Statistiques – Statisztikai célú területi egységek nómenklatúrája) szintű régióinak (megyéinek) gazdasági növekedését elemzi 2000 és 2018 között. A szerzők vizsgálata arra irányul, hogy a közel két évtized alatt elkülöníthetők-e a NUTS 3 régiók hasonló növekedési pályával leírható csoportjai, ún. konvergenciaklubjai, amelyeken belül a térségek ugyanazon klubspecifikus egyensúlyi állapothoz tartanak. A konvergenciaklubok elkülönítésére a Phillips és Sul [2007] által kifejlesztett regresszióalapú konvergenciatesztet, az ún. log t-tesztet használják. A klubokon belüli és klubok közötti egyenlőtlenségek alakulását pedig általánosított Theil-index segítségével mutatják be.
Fotografia na história da arte
Authors:   Universidade de São Paulo, Takami Marina
Published: September 2021

A produção artística atual requer uma revisão das terminologias e das formas de abordar o objeto. Os limites que separavam as diferentes linguagens artísticas foram diluídos. A imagem fotográfica tem presença marcante na produção de arte contemporânea. Neste sentido é relevante que as discussões alcancem as fronteiras mais amplas das artes visuais. Na ocasião da aceitação da fotografia pelo mercado tradicional de arte, ela perdeu, oportuna e momentaneamente, uma de suas características principais: a reprodutibilidade. A fotografia garantiu sua entrada na história da arte por meio de empréstimos estéticos da pintura. Este ensaio aponta algumas reflexões sobre a imagem fotográfica a partir da leitura dos textos “O fotográfico”, de Rosalind Krauss, e “La fotografía plástica: un arte paradójico”, de Dominique Baqué.
Fala cantada: poética e melódica na musicologia de Mário de Andrade
Authors:   Universidade de São Paulo, Teixeira Maurício de Carvalho
Published: September 2021

Texto apresentado no II Encontro de História da Arte.
A arte da cantaria ao longo da estrada real: as produções do século XVIII no caminho do ouro em abordagens multidisciplinares
Authors:   Universidade Estadual de Campinas, Viana Daniela , Pereira Carlos Alberto ,   Universidade Federal de Ouro Preto
Published: September 2021

A comunicação apresenta o projeto em andamento de preservação, ao longo da chamada Estrada Real, do patrimônio material e dos conhecimentos da arte da cantaria desenvolvido em parceria por pesquisadores de universidades de São Paulo e Minas Gerais. Essa experiência multidisciplinar envolve a abordagem de metodologias diversas e serve de base para “o debate e a reflexão crítica a respeito das metodologias utilizadas na produção historiográfica da arte”, como propõe esse II EHA. A arte do trabalho da pedra conhecida como cantaria (abrangendo seus saberes internos, formas de trabalho e produções) é o alvo desse trabalho de levantamento, catalogação e disseminação de conhecimento através da conscientização patrimonial.
Geoarchaeology within the system of archaeological research in the territory of Baikal Siberia
Authors: Berdnikova N.E. , Vorobieva G.A. , Berdnikov I.M. , Shchetnikov A.A. , Filinov I.A. , Lipnina E.A. , Zolotarev D.P.
Published: September 2021

The value of geoarchaeology in archaeological research is discussed with an example of Baikal Siberia. Geoarchaeology is considered as an interface between archaeology and Earth sciences comprising a specific set of approaches, methods, and procedures. Nowadays, geoarchaeology constitutes a full-fledged research branch within the world archaeological practice. However, there are some problems in the determination of the essence and the role of geoarchaeology in archaeological studies, especially in Russia. In particular, the question whether geoarchaeology represents an independent discipline or an interdisciplinary approach has not been resolved yet. Moreover, archaeologists often focus on increasing the number of analytical methods to the detriment of their conceptual basis. In the Russian archaeological practice, the uncertain role of geoarchaeology is manifested by its perception as an auxiliary discipline with limited capabilities for the archaeological interpretations. As a result of many years of research on archaeological sites of Baikal Siberia, we have developed our own concept of geoarchaeology as a source study with a transdisciplinary character. It is based on four principles. Firstly, in our opinion, geoarchaeology constitutes a source study discipline with its own research methods. Geoarchaeological assessment represents one of the most important verification methods aimed at the determination of the degree of correspondence between the results of archaeological and natural science data. Secondly, the main object of research is a geoarchaeological object, which is a composite integral system with a mixture of traces of natural and anthropogenic events encrypted in it. We define the layer with cultural remains, where the natural component predominates, as ‘culture-bearing’. The layer with the predominantly anthropogenic component can be called ‘cultural’. Thirdly, geoarchaeology should be a transdisciplinary branch, the nature of which is determined by the complex origins of the geoarchaeological site. Such an amalgamation allows overcoming disciplinary differences and contradictions which leads to the formation of new knowledge levels. At fourth, geoarchaeological research should be based principally on the methods of actualism and stratigraphy in conjunction with overcoming misidentification of objects and phenomena, as well as on the pedolithological and event-driven approaches.
Stone equipment of the Poludensky complex of the Kedrovy Mys-1 site
Authors: Skochina S.N. , Моsin V.S.
Published: September 2021

The paper deals with the complex analysis of the stone equipment of the Kedrovy Mys-1 site associated with the Poludensky tradition, classical for the Trans-Urals, dated to the Late Neolithic period. On the basis of typologi-cal and functional analyses, aimed at the study of tool shapes and identification of their correlation with the func-tional purpose, specifics of the stone industry of the Poludensky complex have been determined. The tools manu-factured at the site of Kedrovy Mys-1 were produced from the materials from the valley of the river Miass, situated behind the Ilmensky ridge, approximately 20–25 km away from the site. Dominant materials are phtanitoids and sealing-wax green jade; these quality materials were scarce, so that local chalcedonies were used. The stone industry based on the prismatic flaking was aimed at the production of plates as the feedstock for the tools. For the production of tools, preference was given to the medium-width plates, with a little use of small plates. A fea-ture of the complex is represented by the tools indicating the existence of the insert technique, such as plates with the rounded back and face, chamfered tips, “triangle”, and unretouched plates used as knives. Mainly blunting retouching, and sometimes sharpening, was used for the plate processing from the back side. A cutter spalling as the tool shaping technique was used occasionally. No cutters were found. Typologically identified tools are repre-sented by arrow tips, end scrapers, piercers, borers, scrapers on the flakes and nucleus cleavage, chopping tools, abrasives, and a retoucher. Specifics of the Poludensky toolset of the Kedrovy Mys-1 site allows suggestion that during this period of the site the main activity of the population was concerned with food processing — meat cut-ting and catch processing. This is evidenced by the predominance of the knives for meat/fish cutting. The propor-tion of tools used for the production of wooden equipment is quite small, which is probably due to the sampling, although morphologically it is very prominent. In the meantime, the presence of tools for processing of skin, stone, bone, and for repair of ceramics indicates a full cycle of the production activity ensuring efficient adaptation in the lake system environment.
Contrast-enhanced spectral mammography in the radiological assessment of response to neoadjuvant chemotherapy in breast cancer
Authors: Grażyńska Anna , Antoniuk Sofija , Steinhof-Radwańska Katarzyna
Published: September 2021

Accurate morphological assessment and measurement of the residual disease following neoadjuvant chemotherapy are vital for the effective surgical treatment in patients with breast cancer. Neoadjuvant chemotherapy response is measured by RECIST 1.1 criteria (Response Evaluation Criteria in Solid Tumors), and the classification of the specific therapeutic responses is based on the difference in the tumour size prior to and after chemotherapy. There are currently a few methods of imaging used in the assessment of the neoadjuvant chemotherapy response. Conventional mammography remains the most popular method, whereas magnetic resonance imaging is considered the most effective ones. Nonetheless, the available methods tend to be imperfect and limited, and therefore, new methods are constantly investigated. Contrast-enhanced spectral mammography is a relatively new method used in breast cancer diagnosis, which involves the phenomenon of neoangiogenesis of cancerous tumours, allowing contrast enhancement in the areas of vessel proliferation in the background of the surrounding breast tissue. Contrast-enhanced spectral mammography presents sensitivity similar to magnetic resonance imaging in breast cancer detection, and can be an efficient method used in monitoring neoadjuvant chemotherapy response.
Night Parrots Pezoporus occidentalis at the Ethel River, Western Australia: Continuing opportunities for conserving habitats around rare permanent springs
Authors: Curry Peter , Nicholson Charles , Wykes Boyd
Published: September 2021

The combined records of two 20th-century observers (Martin Bourgoin and Julian Ford) of Night Parrots Pezoporus occidentalis at permanent springs on the Ethel River amount to more published records of this elusive bird over a longer timespan (1912–1964) than anywhere else in Western Australia. Likely Night Parrot habitats persisting in the Ethel River area in 2019–2020 include extensive areas of mature Limestone Spinifex Triodia wiseana with other native perennial grasses, hard spinifex on sandplains, patchy perennial tussock grasses on minor floodplains and chenopod shrublands including perennial saltbush. We evaluate these habitats for their past uses and likely continuing changes that might have affected Night Parrots. With a mine under construction upstream in the sub-catchment headwaters and indications that the species is not extinct in the district, there is an urgent need to raise awareness of a uniquely important area and to survey the area for the species. Monitoring and coordinating protective measures across intersecting land uses is likely to improve the future of rare permanent springs and sensitive habitats.
Agriculture Practice and Food Supply in Malaysia for last 50 years
Authors: Moniruzzaman M. , Reza Mohammad Imam Hasan , Khatun Rahima
Published: September 2021

Malaysia is a developing country and agro-industries contribute country’s economy. However, it is largely unknown the scenarios of agricultural practice and food supply over the years. To understand the fact, this study was designed to explore the agricultural land use changes and domestic food supply for last 50 years in Malaysia. The result showed that oil palm plantation area and yield, both are increased by folds, conforming “oil palm” mono-culture practice. Rice cultivation area remained almost unchanged but the yield increased. However, both area of plantation and yield in case of rubber, coca and coconut were decreased. When, it comes to domestic food supply, in 1973 food grain (Rice, Wheat, Maize) import was lower than domestic production. However, the import increased more than 3 times than the domestic production in 2013. Domestic production of vegetables and vegetables import was almost 50:50. Fruits import increased almost 3 times of domestic production, though domestic production was increased. In conclusion, it is understood that Malaysian agriculture economy is standing on “oil palm” wearers domestic food supply is import dependent. It is high time to reshuffle the policy for sustainable development and achieving food sovereignty.
Retrieval of Snow Albedo and Total Ozone Column from Single-View MSI/S-2 Spectral Reflectance Measurements over Antarctica
Authors: Kokhanovsky Alexander , Gascoin Simon , Arnaud Laurent , Picard Ghislain
Published: September 2021

We have proposed a simple algorithm to retrieve the total ozone column and snow properties (spectral albedo and effective light absorption path) using the high spatial resolution single – view MSI/S-2 measurements over Antarctica.
Absorption and Translocation of [14c]2,4-Dichlorophenoxyacetic Scid in Herbicide-tolerant Chromosome Substitution Lines of Gossypium Hirsutum L.
Authors: Perez Loida M , Yue Ziming , Saha Sukumar , Dean Jeffrey F. D. , Jenkins Johnie N , Stelly David M , Tseng Te Ming
Published: September 2021

Upland cotton is sensitive to 2,4-dichlorophenoxyacetic acid (2,4-D), and the identification of potentially 2,4-D tolerant cotton chromosome substitution (CS) lines and understanding tolerance mechanisms provide a significant step into the development and genetic improvement of upland cotton to reduce yield loss caused by 2,4-D herbicide effects including the drifts. Experiments were conducted to understand the possible mechanism of herbicide tolerance in CS-T04-15, CS-T07, and CS-B15sh, 2,4-D herbicide-tolerant cotton CS lines compared with TM-1, the 2,4-D herbicide susceptible recurrent parent of the CS line as control, using [14C]2,4-D. Percent absorption rate and translocation patterns of the 14C-labeled herbicide application at 5.17 kBq at 6 to 48 hours after treatment (HAT) were determined. The tolerant cotton CS lines showed 15-19% [14C]2,4-D uptake while TM-1 exhibited a reduced uptake of only 1.4% [14C]2,4-D at 24 HAT. Distribution of the absorbed [14C]2,4-D showed that 2-5% was translocated outside the treated leaf. In TM-1, 77% of the herbicide was translocated above and below the treated leaf, contrasting with the reduced translocation of 14C-labeled herbicide observed in the tolerant CS lines. Interestingly, CS-T04-15 showed a restricted movement of 14C below the treated leaf at 6 to 48 HAT, suggesting a novel mechanism of herbicide tolerance. This finding is the first report on upland cotton demonstrating a complex differential uptake and translocation associated with herbicide tolerance for [14C]2,4-D in cotton CS lines.
On the properties of the classifier in case of maximal deviations of blood parameters from the norm
Authors: Gavrikov Boris Mikhailovich , Gavrikov Mikhail Borisovich , Pesryakova Nadezhda Vladimirovna
Published: September 2021

A mathematical model is described and implemented, intended for the numerical study of the ability of the statistical classification method to interpolate and extrapolate. The classifier developed by the authors is based on the polynomial-regression approach and has probabilistic estimates. It is used to assess the state of human health based on the parameters of laboratory analysis of peripheral blood. The blood base is considered with a maximal deviation from the norm.
Assessing the seasonal variability of shallow underground waters quality from a volcanic – sedimentary formation during El Niño event in Panama
Authors: Montenegro Mario Luis Miranda , Garcia Ana , Batista Raizha , de Montilla Obdulia , Tapia Arkin , Alvarado Mayubell , Edward Humberto , Olmos Jorge , Lloyd Javier , Hernandez Cecilio , Bayard Carmelo , Pino Alfonso , Caballero Alberto , de Patiño Hildaura Acosta , Villarreal José
Published: September 2021

Providing drinking water to growing populations has become a worldwide concern. Therefore, in many countries some groundwater reserves are now being used to supply drinking water in remote urban areas. The state of these groundwater reserves is strongly influenced by the local geological conditions. Furthermore, climate change has caused a decrease in the periodicity of environmental conditions such as rainfalls, a key driver in replenishing these reserves. In 2019, the weak El Niño event affected the rainfall pattern, as well as physical and chemical quality of shallow ground waters in Panama. Within this study, the northwestern central region of Panama groundwaters have been systematically characterized during El Niño 2018 – 2019 event. Our results indicate that changes in values of physicochemical parameters such as alkalinity, pH and conductivity are related to changes in the amount of rainfall reported in the region starting from dry season (DS) to the rainy season (RS). Chloride was recorded as an indicator of anthropogenic activity and/or the effect of human populations on specific sites in the aquifer recharge zones. Lead (Pb2+), Zinc (Zn2+), Manganese (Mn2+), and Copper (Cu2+) concentrations in the groundwater were evaluated during the DS and RS 2019. Recorded data indicates sub – lethal concentrations of Pb2+, Zn2+, Mn2+ were associated to changes in alkalinity values of groundwater during the DS. While during the RS, a decrease in pH values favored the dissolution of Cu2+ and Zn2+. Our findings suggest that seasonal rainfall deficits modify shallow underground water alkalinity and pH values, inducing the redissolution of Pb2+, Zn2+, Mn2+, Cu 2+and exposing populations to sub – lethal concentrations of those microelements.
Evaluation of Apoptotic Activity of Protein Fusion Enterocin A- Pyocin R-Lactocin, Bacteriocins and Specific Ligand of Gastric Cancer Cell Line (AGS)
Authors: Jalalvand Neda , Bashi Mohammad Mehdi Moghani , Raiszadeh Mohammad , Naeimi Sirous , Esmaeili Davoud
Published: September 2021

Conventional antimicrobial and anti-cancer treatments, including chemotherapy, surgery, radiation therapy, etc., have all been associated with antimicrobial resistance (AMR) and side effects on healthy cell damage. Recently, bacteriocins have emerged as a promising option in antimicrobial and anticancer therapies.In this study, EntA-PynR-Lac gene sequence was obtained using bioinformatics software. The designed fusion gene was synthesized and cloned into the pET22b expression vector and transferred to the engineered E. coli BL21 bacterium for expression of the recombinant protein. The three-dimensional structures and stability of the designed recombinant protein were evaluated. Confirmation and purification of the recombinant protein was performed by Western blotting and nickel column chromatography and determination of cell lethality of different concentrations of the recombinant protein against AGS cell line by MTT technique was conducted. Treatment of cells with different concentrations of protein to evaluate the apoptosis of AGS cells was performed by flow cytometry. The results showed that the percentage of cells treated with recombinant protein at a concentration of 80µg/ml with total apoptosis was 46.91% and increased by 36.25% compared to untreated cells. Due to the anti-apoptotic properties of fusion protein, it can be used to inhibit cancer cells as a therapeutic supplement and prevention.
Closure Versus Non-Closure of Hernia Defect in Laparoscopic Ventral Hernia Repair with Mesh: A Systematic Review
Authors: Aljohani Emad
Published: September 2021

PurposeThere is a controversial premise about choosing a surgical approach in ventral hernia using laparoscopic repair. Some surgeons prefer to use mesh with closure while others prefer to use mesh without closure. This study aims to compare mainly the rate of recurrence in mesh repair with and without closure. MethodsA wide range of electronic bibliographic databases such as PubMed, Embase, and ERIC was searched. Based on the eligibility criteria, all studies which compared the results after hernia repair from 2010 to 2020, were incorporated. Following screening the abstracts, we ended up reviewing seven full-text articles, and data were extracted on important parameters such as demographic attributes of participants, sample size, and recurrence rate of hernia.ResultsOf the total studies that were reviewed, three were randomized controlled trials (RCT’s) and four retrospective observational studies. The sample size of all included studies varied between 80 to 176. The findings appear promising for the fascial closure as it showed an evidence of significant reduction in the recurrence rate with P = 0•047 in one out of the three RCT’s and in the retrospective observational studies reaching up to 16.7 % recurrence reduction rate. Likewise, there is also a reduction in the bulging, surgical site infection and seroma formation with higher patient’s satisfaction and quality of life score.ConclusionPrimary fascial closure appears to be effective as it can decrease the rates of recurrence, seroma formation, bulging and improve patient’s satisfaction and quality of life. Given the dearth of studies, mainly randomized controlled trials, there is a need to carry out large randomized controlled trials with enough follow-up.
Analyzing Trends in Rainfall and Their Impacts in Water Management in a Cerrado Region in Brazil
Authors: Alves welber Ferreira , Roig Henrique , Kalin Latif , Prado Luciana Figueiredo , Satgé Frédéric , Steinke Valdir Adilson
Published: September 2021

This study presents a trend analysis related to a Cerrado Region in Brazil surrounded by multiple climatic influences and which lived a recent water crisis (2016-2018). This crisis could be associated with climatic changes or population growth. To verify the first possibility, an analysis was performed on a series of rainfall data (21 rain gauges spread throughout the region) divided by season periods (December/January/February – DJF, March/April/May – MAM, June/July/August – JJA, September/October/November – SON, and Water Year – WY) to provide information about the presence of trends or lack thereof. Four statistics tests were used in this procedure: Cox-Stuart, Mann-Kendall, Spearman, and Wald-Wolfowitz. The overall results indicate that the percentage of gauges/periods displaying trends by the Mann-Kendall was 10.48%, Cox-Stuart 9.52%, Spearman 12.38, and Wald-Wolfowitz 8.57%. Of these gauges/periods, 70% were classified as highly skewed, 10% as moderately skewed, and 20% as symmetric. Most of the trends are concentrated in the JJA period where it registered about 22 mm of rainfall average while the annual mean total precipitation is ~1500 mm.
IVF Outcome With High Level of AMH: Focus on Pcos Versus Non-pcos
Authors: Muharam R , Prasetyo Yohanes Danang , Prabowo Kevin Ardito , Maidarti Mila , Hestiantoro Andon
Published: September 2021

Background: To investigate whether high AMH level in PCOS patients resulted in different IVF outcomes compared to non-PCOS patients.Methods: A cross-sectional observational study involving 238 women undergoing IVF who have AMH level > 4 ng/ml. Participants then grouped into PCOS and non-PCOS cohorts. Results: The median AMH was significantly higher in the PCOS group (7.59 [4.61] ng/ml vs 5.91 [2.22] ng/ml) (U = 4087, p < 0.001). The PCOS group required less gonadotropin but yielded more oocytes after stimulation. Significantly more participants from PCOS group (41.5% [n=39]) developed hyper-response to ovarian stimulation compared to the non-PCOS group (26.4% [n=38]) (OR = 1.978, 95% CI: 1.138 – 3.488; p = 0.015).Conclusion: Women with PCOS and high AMH levels have a higher risk of hyper-response after ovarian stimulation than their non-PCOS cohorts.