bluuebunny/crossref_metadata_2025 huggingface dataset:
Medicinal chemistry advances in targeting class I histone deacetylases
Authors: Abdallah Diaaeldin I. , de Araujo Elvin D. , Patel Naman H. , Hasan Lina S. , Moriggl Richard , Krämer Oliver H. , Gunning Patrick T.
Published: September 2023

Histone deacetylases (HDACs) are a class of zinc (Zn)-dependent metalloenzymes that are responsible for epigenetic modifications. HDACs are largely associated with histone proteins that regulate gene expression at the DNA level. This tight regulation is controlled by acetylation [via histone acetyl transferases (HATs)] and deacetylation (via HDACs) of histone and non-histone proteins that alter the coiling state of DNA, thus impacting gene expression as a downstream effect. For the last two decades, HDACs have been studied extensively and indicated in a range of diseases where HDAC dysregulation has been strongly correlated with disease emergence and progression—most prominently, cancer, neurodegenerative diseases, HIV, and inflammatory diseases. The involvement of HDACs as regulators in these biochemical pathways established them as an attractive therapeutic target. This review summarizes the drug development efforts exerted to create HDAC inhibitors (HDACis), specifically class I HDACs, with a focus on the medicinal chemistry, structural design, and pharmacology aspects of these inhibitors.
Eating disorders in digestive functional pathology
Authors: López Peñas DL , Villalón García IV , Andrades Ramírez CA
Published: September 2023

Los trastornos de la conducta alimentaria (TCA) son patologías de salud mental graves con una alta mortalidad dentro de los trastornos mentales. Además de las consecuencias físicas que conllevan los TCA, se dan frecuentemente alteraciones del funcionamiento del tracto gastrointestinales que producen sintomatología a nivel digestivo que pueden ser compatibles con los de una patología funcional digestiva (PFD). Puede ser frecuente encontrar en la consulta de gastroenterología pacientes que refieren sintomatología digestiva, la cual puede estar enmascarando un TCA. Por ello, es importante que los gastroenterólogos estén familiarizados con los TCA, puesto que tratar la posible PFD, sin tener en cuenta el TCA, puede agravar la sintomatología del mismo dada las restricciones a nivel alimentario que pueden implicar las pautas dietéticas para patologías digestivas. Del mismo modo, los pacientes con PFD pueden tener un mayor riesgo de desarrollo de alteraciones alimentarias y de TCA en población con factores predisponentes y precipitantes. La relación bidireccional entre las PFD y los TCA hace necesario el conocimiento en estos trastornos por parte de los profesionales que pueden estar en primera línea para prevenirlos y detectarlos, así como para acompañar en un adecuado tratamiento de los mismos.
Sosialisasi Pemanfaatan Eco Enzyme untuk Mengurangi Sampah Organik di Dawis Anggrek Desa Blederan, Wonosobo, Jawa Tengah
Authors: Latifah Siti , Mukhotib Ahmad Atho’ , Nadzir Nadzir , Pamungkas Doni Agil , Hermawan Hermawan
Published: September 2023

Indonesia has a serious waste problem and needs attention from all parties. Waste management can be carried out based on the 4R principle, namely reduce, reuse, recycle and replace. Garbage itself consists of organic and inorganic waste. Organic waste that is over capacity and not managed properly can cause hazards such as odors, affecting water quality, reducing soil quality, and producing methane gas as a contributor to greenhouse gases which can cause environmental damage. One of the efforts to reduce organic waste is through the manufacture of eco enzymes as a natural fertilizer for plants while reducing the greenhouse effect. Activities are carried out through socialization methods and training in making eco enzymes. The results of the activity show that there is an increase in public understanding about the benefits of eco enzyme for the environment as well as how to make eco enzyme by utilizing kitchen waste that is found every day..
Pengabdian Masyarakat dengan “Sosialisasi Pengaruh Penggunaan Gadget pada Anak” di Posyandu Remaja Kelurahan Banyurip
Authors: Ulya Ni'matul , Setyowati Ana , Artanti Swasti
Published: September 2023

The development of advanced technology can increase internet usage in adolescents to spend time every day using social media or the like.  Gadgets have an important role in human life, as technological advances are created to make big changes from children to adults. On the other hand, gadgets have a negative or bad impact if their use is not adjusted to the actual benefits or functions. Socialization of the "Effect of Gadget Use" at the Youth Posyandu of Banyurip Village, Pekalongan City on Friday, February 10, 2023 with 20 participants. This community service activity was very effective and gave significant results with the results of the participants' knowledge before the socialization was mostly in the moderate category, namely 8 people and after socialization the participants had good knowledge as many as 13 people. The author hopes that teenagers, especially in the Banyurip Village area, can have a positive attitude and can manage their time in using gadgets
POSREM (Posyandu Remaja) sebagai Wadah untuk Edukasi Bahaya Merokok pada Remaja
Authors: Maslikhah Maslikhah , Prajayanti Hilda
Published: September 2023

Adolescence is a transition period from children to adults. Teenagers are usually more interested in something new so that teenagers will try to do new things that are not necessarily with the right knowledge, attitudes and actions. Teenage problems are very complex, one of which is smoking behavior and free sex. Free sex can occur by changing boyfriends and girlfriends and smoking can occur due to the life style of adolescents who are influenced by the surrounding environment. The purpose of this activity is to provide education to adolescents about the importance of preventive efforts of juvenile delinquency in terms of free sex and smoking behavior. The method used is by giving pretest, filling in the material, discussion, examination and ending with filling in the post test. The results of this program obtained an increase in adolescents' knowledge about the importance of preventing juvenile delinquency, especially free sex and smoking behavior, which can be seen in the mean value increased by 18.16%. This shows that providing education about the importance of preventing juvenile delinquency, especially free sex and smoking, can increase knowledge.
La argumentación en la enseñanza de las ciencias médicas
Authors: Nassar Tobón Andrea Catalina
Published: September 2023

El uso de la argumentación en la enseñanza de las ciencias conlleva muchos beneficios, incluyendo el desarrollo de habilidades críticas, la promoción del espíritu de investigación, la mejora de la comprensión conceptual y del rendimiento académico. Esta reflexión sustenta la formación en argumentación en profesionales de la salud, exponiendo algunos desafíos implícitos en el quehacer médico. Se plantea la relevancia de integrar la enseñanza de la argumentación, el razonamiento clínico y el aprendizaje basado en problemas. Aunque no existe un modelo ideal de consulta universal, construir argumentos para respaldar perspectivas médicas y sostener diálogos críticos con pacientes son habilidades médicas esenciales.
Prevention and management of hepatitis B virus reactivation in patients with hematological malignancies in the targeted therapy era
Authors: Mak Joyce Wing Yan , Law Alvin Wing Hin , Law Kimmy Wan Tung , Ho Rita , Cheung Carmen Ka Man , Law Man Fai
Published: September 2023

Delayed passage of meconium or constipation during the perinatal period is traditionally regarded as a signal to initiate further work up to evaluate for serious diagnoses such as Hirschsprung’s disease (HD), meconium ileus due to Cystic Fibrosis, etc. The diagnosis of HD particularly warrants invasive testing to confirm the diagnosis, such as anorectal manometry or rectal suction biopsy. What if there was another etiology of perinatal constipation, that is far lesser known? Cow’s milk protein allergy (CMPA) is often diagnosed in infants within the first few weeks of life, however, there are studies that show that the CMPA allergen can be passed from mother to an infant in-utero, therefore allowing symptoms to show as early as day one of life. The presentation is more atypical, with perinatal constipation rather than with bloody stools, diarrhea, and vomiting. The diagnosis and management would be avoidance of cow's milk protein within the diet, with results and symptom improvement in patients immediately. Therefore, we discuss whether an alternative pathway to address perinatal constipation should be further discussed and implemented to potentially avoid invasive techniques in patients. This entails first ruling out CMPA with safe, noninvasive techniques with diet modification, and if unsuccessful, then moving forward with further diagnostic modalities.
SISTEM OTOMATISASI SUHU LUMBUNG PADI BERBASIS ARDUINO
Authors: Risal Muhammad , Affandy Andy Lukman
Published: September 2023

Penyimpan padi (gabah) di lumbung sering terkena masalah-masalah, seperti masalah hama Gudang, gangguan tikus dan juga masalah ketika terjadi curah hujan yang tinggi sehingga menyebabkan suhu di dalam lumbung menurun sehingga terjadi lembab maka pada akhirnya padi yang disimpan rusak menghitam akibat terkena jamur serta juga ketika suhu matahari yang terlalu panas maka dapat menyebabkan padi di dalam lumbung rusak atau mudah hancur sehingga dapat mempengaruhi mutu dan kuliatasnya. Penelitian ini bertujuan untuk merancang dan mengimplementasikan sistem otomatisasi suhu lumbung padi berbasis arduino, menggunakan sensor DHT11 sebagai sensor mendeteksi suhu dan kelembaban serta blower untuk menaikkan suhu dalam lumbung, menggunakan arduino sebagai pemroses sistem. Prototype lumbung padi bekerja secara otomatis dalam mengontrol suhu dan kelembaban pada lumbung. Sistem bekerja pada suhu 280C - 400C dimana blower akan bekerja memanaskan ruangan dan akan berhenti bekerja jika suhu telah melebihi 400C. Pada pengujian sistem terdapat rata-rata margin error sebessar 2,6% antara data yang ditampilkan pada LCD dengan pengukuran secara manual menggunakan termometer.
RANCANG BANGUN SISTEM MONITORING DAN PENYEMPROTAN GULMA RUMPUT PADI BERBASIS ANDROID
Authors: S. Kom., M.Kom. Guntur, , Agus Muh .
Published: September 2023

Rumput padi (gulma berdaun sempit) adalah rumput liar yang sering tumbuh di sekitar tanaman padi, apabila tidak diatasi dengan benar maka petani akan mengalami kerugian berupa penurunan hasil panen dari tanaman yang dibudidayakan. Untuk itu diperlukan suatu alat yang dapat memonitoring dan melakukan penyemprotan secara otomatis untuk memudahkan serta mengurangi beban kerja petani jika lahan yang digarap cukup luas. Metode penelitian yang digunakan adalah metode waterfall. Pada penelitian ini digunakan beberapa komponen rangkaian yaitu antara lain: Arduino mega 2560 sebagai kontroler dan Arduino IDE yang digunakan dalam aplikasi pemprogramannya. Arduino mega menjadi pusat data dan control terhadap semua komponen yang terhubung.. System operasi dibangun menggunakan Bahasa pemprograman C. Pada penelitian ini digunakan luas lahan 11 X 3 Meter2.. Hasil Kinerja dari system ini menunjukkan bahwa dibutuhkan 4 buah sprinkle untuk dapat menyemprot luas lahan seluas 11 X 3 Meter2. Keadaan rumput yang telah disemprot mati dalam jangka waktu 11 hari.
Aplikasi APLIKASI PENGENALAN RUMAH ADAT SULAWESI SELATAN DENGAN MENGGUNAKAN AUGMENTED REALITY
Authors: T Muh Alwi , Umar Najirah , Haris Yuliah
Published: September 2023

Sulawesi Selatan merupakan provinsi yang kaya akan ragam, budaya dan suku.Tapi meski memiliki keberagaman kebudayaan yang cukup banyak, namun masyaraktnya sendiri banyak yang belum mengetahui rumah adat tersebut. Penelitian ini, (1) Untuk merancang aplikasi pengenalan rumah adat Sulawesi Selatan menggunakan teknologi Augmented Reality,(2) Mengimplementasikan rumah adat dalam bentuk 3D.Augmented Reality dapat dimanfaatkan sebagai media pengenalan rumah adat Sulawesi Selatan yang di tampilkan dalam bentuk 3D. Dalam penelitian ini untuk membuat objek 3D digunakan Software Blender  dan untuk memunculkan objek 3D menerapkan teknik User Defenied Target, yaitu mengenali objek sebagai marker dengan syarat objek itu memiliki kombinasi warna lebih dari satu. Dalam metode markerless penggunaan tanda marker dan frame marker sebagai tracking object sudah digantikan dengan pengenalan pola (pattern Recognition) pada objek. Ketika melakukan pelacakan, markerless akan melakukan perhitungan posisi antara kamera atau lensa yang digunakan oleh pengguna dengan objek pada dunia nyata, lalu merefleksikan hanya dengan menggunakan titik-titik pada fitur alami MAR seperti: edge, corner, garis ataupun objeck 3D. Selanjutnya dilakukan langkah priori manual, serta penggambaran model sebagai referensi untuk inisialisasi objek. Dengan demikian, keakuratan objek yang didapat serta objek yang akan divisualisasikan dari proses tracking dan pattern recognition akan lebih baik dan tinggi. Hasil uji implementasi kepada 25 responden diperoleh hasil dari aspek rekayasa perangkat lunak 72% bernilai baik, aspek komunikasi visual bernilai sangat baik sebesar 68%, dan aspek Fungsionalitas bernilai sangat baik sebesar 76% sehingga layak untuk digunakan
PENINGKATAN PELAYANAN PELANGGAN DENGAN MEMBANGUN SISTEM INFORMASI MANAJEMEN SERVICE PADA CV EDO PRIMA COMPUTAMA
Authors: Wijaya Yahya Dwi
Published: September 2023

Dalam menjalankan proses bisnis, CV Edo Prima Computama memiliki kendala di pelayanan informasi pelanggan. Kendala tersebut adalah kurangnya optimalisasi peayanan inforamsi service dan manajemen data service. Dalam melakukan pelayanan informasi pelanggan service CV Edo Prima Computama, hanya menggunakan media komunikasi whatsapp saja. Salah satu kelemahan pelayanan melalui whatsapp adalah pelanggan harus menunggu waktu respon dari admin yang terkadang menunggu waktu yang lama apabila admin belum online. Dalam melakukan pencatanan transaksi, CV Edo Prima Computama masih memikiki ketergantungan menggunakan kertas nota. Pengelolaan data service dilakukan oleh admin dari kertas ke excel kemudian dikirimkan ke atasan. Untuk mengatasi permasalahan tersebut maka dibutuhkan sistem inforamsi manajemen yang digunakan untuk optimalisasi pelayanan pelanggan dan pengelolaan data service. Sistem informasi yang dibangun menggunakan metode extreme programing. Sistem informasi yang dihasilkan memiliki fitur untuk rekapitulasi data service pelanggan, pengelolaan data service pelanggan, layanan informasi riwayat service pelanggan, dan unduh nota digital.
ANALISIS PENERIMAAN DAN PENGGUNAAN APLIKASI PLATFORM FAN COMMUNITY WEVERSE MENGGUNAKAN TECHNOLOGY ACCEPTANCE MODEL(TAM)
Authors: Cantika Imelda , Ary Maxsi
Published: September 2023

Weverse adalah komunitas K-Pop sebagai penggemar resmi tempat bagi penggemar dan artis berinteraksi. Aplikasi fandom weverse merupakan alat yang dapat berkomunikasi dengan para idola mereka. Penggemar mendapatkan akses konten eksklusif, membeli merchandise, dan berbincang-bincang dengan para idola. Tujuan penelitian ini untuk mengetahui penerimaan dan penggunaan aplikasi Weverse menggunakan Technology Acceptance Model (TAM). Metode penelitian yang digunakan yaitu Technology Acceptance Model dengan 3 variabel, yaitcu perceived usefulness (PU), perceived ease of use (PEOU), dan attitude toward using (ATU). Sampel penelitian merupakan pengguna aplikasi weverse yang berjumlah 87 responden. Berdasarkan hasil penelitian dan pengujian hipotesis menggunakan SPSS 20, didapatkan hasil bahwa PEOU tidak berdampak signifikan terhadap ATU dengan tingkat hubungan 0.033 = 0,33% dan PU berpengaruh signifikan terhadap ATU dengan tingkat hubungan 0.522 =52,5%, PEOU dan PU berpengaruh signifikan terhadap ATU dengan R Square 0.300 = 30%.

Kata kunci: Technology Acceptance Model, Aplikasi Weverse
Analsis Sistem Pendukung Keputusan Seleksi Karyawan Tetap Dengan Menggunakan Metode Multifactor Evaluation Proses Pada PT. Pharos Indonesia
Authors: Ismiyati Ummi , Idrus Arnida , Indraswari Ririn
Published: September 2023

Abstrak : Penelitian ini bertujuan untuk : (1) merancang suatu sistem pendukung keputusan yang dapat memberikan kemudahan bagi panitia seleksi karyawan tetap dalam memberikan keputusan tentang hasil dari seleksi karyawan tetap tersebut. (2) mengemplementasikan aplikasi sistem pendukung keputusan seleksi karyawan tetap pada PT. Pharos Indonesia. Penelitian ini dilakukan pada PT. Pharos Indonesia Makassar. Perancangan Sistem Pendukung Keputusan Seleksi karyawan tetap pada PT. Pharos Indonesia dimaksudkan untuk meningkatkan efektifitas dan efesiensi waktu dalam hal pengambilan keputusan untuk seleksi karyawan tetap. Hasil dari penelitian menunjukkan bahwa sistem yang dirancang ini sangat mendukung Keputusan Seleksi Karyawan Tetap pada PT. Pharos Indonesia dengan memberikan kemudahan dalam pengambilan keputusan yang objektif dan transparan.
MONITORING SUHU DAN KELEMBAPAN BERBASIS THINGSPEAK PADA RUMAH JAMUR TIRAM
Authors: Habibuddin Julianti
Published: September 2023

Budidaya jamur tiram memerlukan perawatan dan perlakuan khusus sehingga jamur dapat tumbuh seperti lingkungan alaminya. Mengetahui suhu dan kelembapan rumah menjadi hal yang penting untuk proses penyiraman yang merupakan langkah untuk menjaga kelembapan rumah jamur. Pada beberapa industri kecil menengah (IKM) jamur tiram melakukan proses penyiraman rumah jamur secara manual apabila cuaca panas (masih memperkirakan suhu ruangan belum berbasis data). hal tersebut kurang efektif sehingga dibutuhkan penelitian perancangan alat monitoring suhu dan kelembapan berbasis thingspeak. Pada perancangannya digunakan sensor DHT22 yang berfungsi mendeteksi suhu dan kelembapan pada rumah jamur. Mikrokontroller yang digunakan berupa nodeMCU ESP32 yang dapat terhubung dengan platform IoT. Platform Iot yang digunakan untuk memonitoring suhu dan kelembapan rumah adalah ThingSpeak. Berdasarkan hasil penelitian diperoleh waktu pengamatan 10 menit yaitu pukul 21:15 – 21:25 di peroleh nilai suhu 26,3º - 26,4º C dan kelembapan 95 – 97% sehingga pada waktu tersebut tidak perlu dilakukan penyiraman karena suhu dan kelembapan memenuhi untuk suhu ruang rumah jamur tiram yaitu suhu 22º - 28º C dan kelembapan 70-90%.
SISTEM REAL-TIME UNTUK PEMBELAJARAN TARI 4 ETNIS SULAWESI SELATAN
Authors: Gani Hamdan
Published: September 2023

Properti dan potensi budaya yang mulai dilupakan dan kurang dimanfaatkan secara maksimal oleh pemerintah Indonesia menimbulkan banyak persoalan, salah satunya adalah klaim budaya tari oleh negara lain. Penelitian ini bertujuan (1) mengimplementasikan sistem pembelajaran yang mampu melakukan proses pelacakan fitur objek bergerak dan proses pengenalan gerakan secara sistem real-time (2) mengimplementasikan sistem pembelajaran untuk melihat manfaat belajar siswa menggunakan sistem yang diusulkan pada penelitian ini. Implementasi sistem pembelajaran dilakukan dengan menggunakan algoritma tracking dan algoritma recognition (Dynamic Time Warping). Studi kasus penelitian dilakukan pada tarian empat etnis dari Sulawesi Selatan. Sistem diuji menggunakan uji fungsional sistem dan uji manfaat menggunakan statistik komparatif dengan T-test. Hasil penelitian menunjukkan bahwa keluaran Rekognisi gerak tari secara parsial memiliki nilai akurasi sebesar 87,26 %, sedangkan total MSE pengenalan sebesar 0,02 untuk Threshold=2. Selanjutnya, uji statistik komparatif digunakan untuk membandingkan hasil ujian siswa dalam dua kelas sampel. Salah satu kelas menggunakan sistem pembelajaran, sedangkan yang lain tidak menggunakan. Uji T menunjukkan bahwa nilai signifikansi 0,000 < 0,01 pada tingkat signifikansi 99%. Artinya terdapat perbedaan yang signifikan antara siswa di kelas yang menggunakan sistem pembelajaran tari yang diusulkan dengan siswa yang berada di kelas tanpa sistem pembelajaran pada mata pelajaran seni rupa.
Pendampingan Pelaporan Pajak Menggunakan E- Filing
Authors: Nurjanah Yayuk , Zulkarnain Pingky Dezar , Sutjipto Suci Sri Utami , Gracia Shania
Published: September 2023

Ciawi Pratama Tax Service Office (KPP) is an office engaged in taxation for public services with the aim of obtaining revenue in conducting tax reporting activities. The DJPOnline system is an application system built on a web-based basis which was developed as a means where taxpayers can register and report their tax obligations online and can be accessed anywhere. This application is connected in real time with the tax information system that is already running at the Ciawi Pratama Tax Service Office. The purpose of the discussion is to find out tax reporting services andtax reporting procedures online using e-Filing. The purpose oftax reporting online using e-Filing is to assist taxpayers in reporting in real time and can be done anywhere without the need to go to the Tax Service Office.The results of the discussion show that the online tax reporting procedure uses e-Filing to help taxpayers to be able to report their taxes in real time and can be done anywhere without the need to go to the Tax Service Office, with a connected internet network and an active email in the DJPOnline account. .

 

Keywords ; Procedure, Tax Reporting, e-Filing
Pelatihan Optimasi Media Sosial Untuk Peningkatan Omzet UMKM
Authors: Kusuma Rahma Djati , Sutjipto Suci Sri Utami , Sujana Sujana , Maretha Hildha Aulia
Published: September 2023

This community service activity (PKM) aims to increase UMKM players' understanding of the importance of social media for business continuity, then provide guidance so that UMKM have an Instagram account for business and can use it effectively in accordance with best practices. This Social Media Optimization Training for Increasing UMKM Turnover is expected to provide understanding and the ability of UMKM players in using their business social media accounts so that they have an impact on business development and increase their turnover.

The methods used in this training include (1) lectures to explain current Indonesian digital data, (2) discussion to find out the problems faced by UMKM related to social media, and (3) simulation as a practical session so that it is hoped that UMKM actors will better understand and master how. use of Instagram social media for business.

This PKM activity has been carried out and is running smoothly in accordance with the objectives to be achieved, and getting good results. In general, the training participants, namely 100 UMKM champions in Bogor City, gave a positive response to the overall implementation of the training. This is because the material they get from this training is in accordance with their needs and is packaged in a fun event. Full support and appreciation from the Head of the Bogor City Cooperative and UMKM Office was given to the implementation team and the LPPM of the Unitary Business and Informatics Institute starting from the assessment or observation stage, to the implementation of training. The collaboration that has been established between the Unitary Business and Informatics Institute with UMKM actors as well as the Bogor City Cooperative and UMKM Office is expected to continue and be developed in the future as a form of implementing the Tridharma of Higher Education.

 

Keywords: social media, UMKM
Penerapan Hukum Bisnis Sebagai Upaya Menstimulus Kinerja Umkm Dalam Perspektif Marketing
Authors: Noor Tubagus Dicky Faldy Syahid , Nurendah Yulia , Suardy Weman
Published: September 2023

Micro, Small, and Medium Enterprises are business activities that are able to expand employment opportunities and provide broad economic services to the community, and can play a role in the process of equity and increase people's income, encourage economic growth and play a role in realizing national stability. MSMEs need knowledge related to the legalization of designs, packaging, for example the procedures for registering products for Trademarks, Copyrights, Industrial Designs and brand disputes.

 

Keywords: Legality, Micro, Small, and Medium Enterprises, SWOT
PKM-Pendampingan Tehnik Pembuatan Konten Promosi Digital Bagi UMKM Kota Bogor
Authors: Pradana Egi Adithia , Damatraseta Febri
Published: September 2023

Dalam membina dan mengembangkan UMKM di Kota Bogor, diperlukan wadah yang berfungsi sebagai pembinaan dan pelatihan yang dilakukan secara terus-menerus. Kegiatan Pengabdian Kepada Masyarakat (PKM) ini bertujuan agar UMKM yang bernaung dibawah LPPM Institut Bisnis dan Informatika Kesatuan dapat menambah kemampuan dan pengalaman dalam membuat konten digital terkait dengan promosi produk mereka.

Dalam pelatihan ini menggunakan beberapa metode antara lain (1) ceramah untuk memaparkan pentingnya konten digital dalam promosi, (2) diskusi untuk mengetahui permasalahan yang dihadapi UMKM membuat konten digital, dan (3) simulasi sebagai sesi praktik sehingga diharapkan pelaku UMKM lebih memahami dan menguasai cara membuat konten dengan media digital sebagai sarana promosi bisnis.

Kegiatan PkM-Pendampingan Tehnik Pembuatan Konten Promosi Digital Bagi Umkm Kota Bogor telah dilaksanakan dan berjalan dengan lancar tanpa hambatan berarti dan sesuai dengan tujuan yang ingin dicapai, serta mendapatkan hasil yang baik. 100 UMKM Juara Kota sebagai peserta pelatihan Bogor juga memberikan respon yang positif terhadap pelaksanaan pelatihan. Hal ini disebabkan mereka mendapatkan materi dari pelatihan ini sesuai dengan kebutuhan dan kegiatan pelatihan tidak monoton kegiatan pelatihan ini didukung sepenuhnya oleh Dinas UMKM Kota Bogor dengan bekerja sama dengan LPPM IBI Kesatuan sebagai penyelenggara kegiatan pelatihan, diharapkan kegiatan seperti ini akan terus ada secara kontinyu dan menghasilkan pelaku UMKM kota Bogor unggulan.

 

Kata kunci: Media Digital, UMKM
Pelatihan Buzz Marketing Pada Sepatu Adidas
Authors: Rainanto Bambang Hengky , Damatraseta Febri , Pradana Rafli
Published: September 2023

Buzz Marketing or word of mouth is an important attribute of Buzz Marketing. There are four attributes in Brand Equality from Brand Awareness , namely Association Brand ,, apartPrecieved Quality (perceived quality), Brand Loyalty (Brand Loyalty) and Other Proprientary Brand Assets (brand assets). other). There are four levels in Buzz Marketing, namely: Top Of Mind , Brand Recall , Brand Recognition , and Unware of Brand . In this review, it only focuses on "Overview of Buzz Marketing in Adidas Shoes", the purpose of this final project is to find out where Adidas is in thePyramid Buzz Marketing. Based on the research results show that Buzz Marketing has an important role in the introduction of adidas shoe products. Good marketing quality can foster high customer satisfaction.

 

Keywords: Buzz Marketing, Top of Mind, Brand Recall, Brand Recognition Unaware of Brand
Pelatihan Penerapan Potongan Harga Pada Layanan Dompet Digital OVO
Authors: Mulyana Mumuh , Roup Abdul , Sulastri Sulastri
Published: September 2023

The research method used is a case study, which takes one particular object for in-depth analysis by focusing on one problem. The data used are primary data and secondary data. Primary data were collected through questionnaires and direct observation with the customers of PT. International Visionet (OVO), while secondary data were obtained from books and other sources.

Based on the results of the study, it shows that the digital wallet service of PT. Visionet Internasional is in the good category, this can be seen from the large number and increasing number of digital wallet service (OVO) users, and with various promos that customers can enjoy at various merchants, it keeps its users loyal to using digital wallet (OVO) services. With the discount, it has an impact on the customer's desire to re-establish cooperation and even recommends others to participate in using the digital wallet service application (OVO).

 

Keywords: Service, OVO Digital Wallet
Pendampingan Dan Pelatihan Inovasi Kemasan Produk Bagi Umkm Kota Bogor
Authors: Pambudi Arde Lindung , Yusdira Ade , Mashadi Mashadi
Published: September 2023

Kemasan (packaging) merupakan salah satu ujung tombak penjualan suatu produk. Kemasan mempunyai peranan yang sangat penting karena akan selalu terkait dengan komoditi yang dikemas dan sekaligus merupakan nilai jual dan citra produk. Nilai jual ini meningkat ketika produk yang dihasilkan mendapat nilai tambah dari kemasan yang menarik. Sedangkan citra produk terkait dengan gambaran produk dalam benak konsumen akan semakin baik apabila produk itu dikemas secara baik, dengan kata lain produk dapat memberi kesan baik bagi konsumen. Tujuan umum dari kegiatan ini adalah memberikan pelatihan tentang bagaimana para pelaku usaha UMKM Kota Bogor dapat mengembangkan kemasan produk agar produk yang dihasilkan banyak diminati oleh konsumen sehingga mereka dapat mengembangkan usahanya dengan baik dan mampu memberikan kontribusi bagi pembangunan ekonomi di Kota Bogor.
Women s' perception on role of breast self-examination in early breast cancer detection
Authors: Uzma Kausar  , Amir Ahmad  , Muhammad Sohail Anjum Noor  , Areeba Sohail
Published: September 2023

BACKGROUND & OBJECTIVE: A good knowledge of the predictive and precepting factors can reduce the risk of breast cancer. This study aimed to assess female patients' knowledge of breast cancer, self-examination techniques, and other screening methods.

METHODOLOGY: A cross-sectional descriptive study was carried out at the territory care hospital Khurrianwala Faisalabad, including 500 women attending the outpatient department from June 2022 to November 2022 after taking informed consent. Data collected by filling out a validated questionnaire was analyzed through SPSS software version 22.0. Relationships between categorical variables were tested by using the chi-square test, and a p<0.05 is considered highly significant.

RESULTS: Out of 500 study participants, 304(60.8 %) know about breast cancer, of which 64(12.8 %) have a positive family history, 436(87.2 %) have no history of breast cancer, and 196(39.2%) were unaware of breast cancer. Out of the total participants, 60.8 % were aware of Breast self-examination, while 39.2% did not know. There is a significant association for the practice of breast self-examination in the population above higher education p-value≤0.001. Similarly, occupation p-value≤0.001, marital status p-value=0.040, and education p-value≤0.001 have significant associations with BSE.

CONCLUSION: The current study showed that knowledge of breast cancer and the practice of BSE and mammography were very poor. A health education program involving the local and governing bodies should be organized to reduce the prevalence and create awareness.
La educación en el Siglo XXI Desafíos y Oportunidades
Authors: Calderón Sánchez Dr. Edgar Ricardo
Published: September 2023

La educación en el Siglo XXI Desafíos y Oportunidades
Analisis Forensik Digital Pada Whatsapp Dan Facebook Menggunakan Metode NIST
Authors: Ruslan Takdir , Riadi Imam , Sunardi Sunardi
Published: September 2023

Technological developments can make it easier for Smartphone users to share various kinds of information using instant messaging applications such as Facebook Messenger and WhatsApp, the features contained in these instant messaging applications can send messages in the form of text, audio, images, videos and documents. The increase in the number of users of instant messaging applications also has a negative impact, namely the emergence of individuals who abuse instant messaging applications for digital crimes such as fraud, pornography, and drug sales. Disclosure of crimes requires valid digital evidence. In conducting investigations of digital crime cases, digital evidence is needed to solve them. Retrieval of digital evidence requires a forensic process of the physical evidence that has been obtained. This research focuses on the forensic process to obtain digital evidence from an Android Smartphone in the form of audio and video in the Facebook Messenger and WhatsApp applications. The forensic tools used in this research are Oxygen Forensic Pc Suite 2014, MOBILedit Forensic, Belkasoft evidence, and Magnet Axiom. The research uses a framework from the National Institute of Standards and Technology (NIST). The results of the research using the NIST method on an Android Smartphone were that Belkasoft succeeded in recovering deleted data with a percentage of 50% audio and 41% video on the WhatsApp application while on Facebook Messenger only 8.33% audio and 41% video, Magnet Axiom with a data percentage of 100%. audio and 100% video while Facebook Messenger has 8.33% audio and 5% video, on MOBILedit with a percentage of 0% on both applications, and Oxygen manages to return 16.67% audio and 23.5% video from the WhatsApp application and 0% for Facebook Messenger
PRIMEIROS CASOS DE INFECÇÃO PELO VÍRUS DA FEBRE DO NILO OCIDENTAL EM EQUINOS NO ESTADO DE SÃO PAULO: FIRST CASES OF WEST NILE FEVER VIRUS INFECTION IN HORSES IN SÃO PAULO STATE
Authors: Farinelli De Siqueira Renata , Hansen V. S. , Martins M. F. M. , Bondan E. F.
Published: September 2023

O vírus da Febre do Nilo Ocidental (WNF) foi relatado no Brasil em soro de equinos e aves em 2008 na região centro-oeste, em 2013 na Paraíba, em 2014 no Piauí e em 2018 no Espírito Santo. É um membro da família Flaviviridae do gênero Flavivirus, neurotrópico, que infecta várias espécies de mamíferos, sendo humanos e equinos os mais suscetíveis. Aproximadamente 35% dos cavalos desenvolvem sinais clínicos, sendo considerados as melhores sentinelas para essa doença. Em 2019, dois equinos com sintomatologia neurológica foram atendidos no hospital veterinário da Universidade Cruzeiro do Sul (São Paulo, S.P.). O primeiro apresentou sintomas como fraqueza e convulsões esporádicas e se recuperou, sendo internado quinze dias depois com insuficiência renal e laminite. O segundo apresentou incoordenação, fraqueza de membros pélvicos, andar em círculos, evoluiu para convulsões e os dois animais foram eutanasiados. Amostras de sangue ambos os cavalos foram enviadas para exames de raiva, herpes vírus e WNF, com resultados negativos para os 2 primeiros. RNAs foram extraídos das hemácias mediante uso da técnica da reação em cadeia da polimerase (PCR) in house. Os produtos da amplificação por RT-PCR específicos para a WNF foram obtidos usando uma combinação de nested PCR e PCR multiplex. Relatamos aqui os primeiros casos confirmados de WNF na cidade de São Paulo e alertamos para a inclusão dessa doença no diagnóstico diferencial em cavalos com afecções do sistema nervoso.
REFUGIADOS VENEZUELANOS NO BRASIL: CONTEXTO PRECEDENTE, PROCESSO DE INTERIORIZAÇÃO E DESAFIOS A INTEGRAÇÃO LOCAL
Authors: SANTOS Robério Gomes dos , SANTOS Antônia Gabrielly Araújo dos
Published: September 2023

A problemática a respeito dos refugiados venezuelanos no Brasil vem gerando reflexos na sociedade brasileira, ante aos milhares que ingressam no país em busca de refúgio. O objetivo geral deste trabalho é discutir a questão dos refugiados venezuelanos no Brasil, os objetivos específicos são: apresentar breve contexto histórico da crise humanitária da Venezuela; analisar o trabalho da Operação Acolhida; e investigar as dificuldades encontradas pelos refugiados venezuelanos para a integração na sociedade brasileira. A metodologia utilizada foi a pesquisa bibliográfica de artigos, doutrinas, e produções correlatas que tratem sobre refugiado venezuelanos, sobre a operação acolhida, com a abordagem de pesquisa descritiva, explicativa e quantitativa. Foi possível concluir que: a) A crise político-econômica e social da Venezuela tem levado milhares de venezuelanos a buscar refúgio no Brasil, para fugir das violações aos direitos humanos; b) O trabalho realizado pela operação Acolhida tem uma enorme contribuição na acolhida dos refugiados venezuelanos em nosso país, tendo realizado a interiorização de milhares de venezuelanos, possibilitando nova oportunidade de vida no Brasil; c) Ainda existem muitos desafios a serem superados para a integração dos refugiados venezuelanos no Brasil, como os preconceitos, xenofobia, desconhecimento do idioma português, acesso aos serviços públicos brasileiros, dente outros.
O SISTEMA ÚNICO DE SAÚDE - DIANTE DA COVID- 19: O FARMACÊUTICO NO COMBATE À PANDEMIA
Authors: De Oliveira Mirelly Dutra , Lacerda Luiza Gobira , Mendes Ronivaldo Ferreira , Coelho Viviane Amaral Toledo , Nascimento Ednardo de Souza , Coelho Thomaz , Lopes Lívia Alves Rezende , Machado Anna Lethicia de Oliveira , Campos Sandy Ribeiro , Cruz Arthur Botelho Benevides
Published: September 2023

A Covid-19 é uma doença cuja dimensão alcançou níveis pandêmicos rapidamente, atingindo várias regiões do mundo, com diferentes impactos. A pesquisa trata-se de uma abordagem qualitativa, de caráter exploratório, compreensivo, explicativo. Esse estudo tem a intenção de apresentar os aspectos clínicos, epidemiológicos e terapêuticos sobre o Covid-19, bem como compreender o papel desenvolvido pelo farmacêutico e pelo Sistema Único de Saúde – SUS. Em virtude de ser uma doença nova e recente, as estratégias de enfrentamento foram acontencendo comcomitantemente ao avaço da pandemia. O mesmo se deu quanto aos aspectos clínicos e epidemiológicos. O diagnóstico do coronavírus é feito com o auxílio de exames que identificam material genético, antígenos e anticorpos. O farmacêutico, deve auxiliar os clientes pacientes que acessam as farmácias públicas, privadas e comunitárias, contribuindo com a identificação de casos suspeitos. O estudo descreve as caracerísticas gerais da infecção, apontando dados e sua evolução no período analisado, bem como expõe as suas prinicpais características e desagios impos aos serviços de saúde, especialmente no Brasil, a atuação do Sistema Único de Saúde (SUS) no enfrentamento dos desafios impostos. De modo incipiente, apontou as regras gerais iniciais para utilização dos testes diagnóstics, seus critéiros de validaçãono Instituto Nacional de Controle de Qualidade em Saúde (INCQS)/Fiocruz e sua diversidade de utilização e aplicabilidade.
CONTRIBUIÇÕES DO SOFTWARE GEOGEBRA NO ENSINO E APRENDIZAGEM DA ÁLGEBRA MATRICIAL E VETORIAL
Authors: Santana Fabiana Tristão , Santana Fágner Lemos
Published: September 2023

O objetivo deste trabalho é mostrar algumas contribuições que o uso da Janela CAS do software GeoGebra pode trazer ao ensino e aprendizagem da álgebra matricial e vetorial nos cursos de Engenharias. A escolha dos temas abordados se deu pela grande aplicabilidade e pelo fato deles abrangerem conceitos abstratos, frequentemente mal compreendidos por muitos estudantes. Para isso, apresentaremos os principais comandos da linguagem utilizada na Janela CAS que permitirão o desenvolvimento de uma programação elementar e fácil de ser compreendida. Exploraremos os conceitos de vetores, matrizes e sistemas lineares nesse ambiente computacional utilizando alguns exemplos e, como resultado, teremos um tutorial com alguns modelos que poderão ser usados por professores e alunos para elaborar novas questões e para resolver problemas. A familiaridade com o software e o conhecimento das informações apresentadas nesse trabalho garantirão autonomia para os interessados se aprofundarem ainda mais e perceberem como esta ferramenta pode facilitar o desenvolvimento das atividades dos docentes e dos estudantes.
ANÁLISE MULTIVARIADA NA COMPARAÇÃO DE ATRIBUTOS NUTRICIONAIS E TECNOLÓGICOS DE GRÃOS DE FEIJÃO CARIOCA ORGÂNICO E CONVENCIONAL ARMAZENADOS
Authors: Cassol F.D.R. , Coelho S.R.M. , Fortes A.M.T.
Published: September 2023

Os atributos nutricionais e tecnológicos conferem a qualidade dos feijões e são baseados em um conjunto de variáveis. O uso da análise das componentes principais (APC) e de agrupamento (Cluster) contribuem para a diminuição do número de dados apresentados, melhorando a interpretação dos dados originais. Sendo assim, o objetivo deste trabalho foi usar técnicas multivariadas para determinar as variáveis que mais influenciam na qualidade dos feijões e verificar as semelhanças entre as formas de conservação e modo de produção dos feijões carioca. Foram empregados os dados de proteínas, ácido fítico, taninos, capacidade antioxidante, teores de cálcio, ferro e fósforo, componentes de cor (C*, H* e L*), teor de água, massa de grãos, capacidade de hidratação, tempo de cocção, textura dos feijões cozidos e embebidos de oito cultivares de feijões orgânico e convencional, recém-colhidos, armazenados sob refrigeração e em condições ambientais, foram utilizados nas análises de APC e o Cluster. Com o uso da APC foram definidas as variáveis que mais influenciaram a qualidade dos feijões sendo elas proteínas, cálcio, fósforo, ácido fítico, taninos, a capacidade de hidratação e antioxidante, o tempo de cocção, a massa dos grãos e ângulo de coloração (H*). A utilização do Cluster possibilitou classificar os cultivares em grupos e verificar que o armazenamento refrigerado foi eficaz na manutenção da qualidade, além disso, essa técnica mostrou a semelhança entre os feijões orgânicos e convencionais pertencentes ao mesmo cultivar.
ESTUDO DOS EFEITOS BIOLÓGICOS DO EXTRATO AQUOSO DA FLOR DA ESPÉCIE TARAXACUM OFFICINALE SOBRE A FRAÇÃO DE SOBREVIVÊNCIA DA CEPA ESCHERICHIA COLI AB1157
Authors: Cruz Thayná Faria , Nascimento Claudia Cristina Hastenreiter da Costa , Feliciano Gláucio Diré , Vasconcelos Suzy Darlen Dutra de , Stephens Paulo Roberto Soares , Barreto Alaide de Sá
Published: September 2023

Objetivo: Analisar os efeitos biológicos de extratos aquosos, obtidos a partir das flores de espécimes de Taraxacum officinale conhecida através nome popular de Dente-de-Leão, correlacionando com suas ações farmacológicas presentes em literatura. Métodos: O material botânico contendo a parte das flores da Taraxacum officinale para a Preparação do Extrato Aquoso realizou-se a preparação do Meio de Cultura para o Ensaio de Sensibilidade Antimicrobiana (Disco-Difusão), Reativação da cepa de Escherichia Coli AB1157, Cepa Bacteriana avaliada, Teste de Sensibilidade Antimicrobiana (Disco-Difusão) e a Análise estatística. Resultados: obteve-se pelo teste de sensibilidade antimicrobiana, denominado difusão em disco, onde foi avaliada a ação do extrato aquoso da flor da planta Taraxacum officinale sobre a fração de sobrevivência da cepa selvagem Escherichia coli AB1157 e comparados com o estudo já pré-existentes, sobre a mesma linha de pesquisa realizado na mesma instituição, do extrato aquoso das folhas e ramos da planta Schinus terebinthifolius Raddi. Conclusão: Pode-se observar que o extrato aquoso da flor da Taraxacum officinale apresentou uma maior significância com relação aos valores médios do diâmetro do halo de inibição do crescimento bacteriano do que o extrato aquoso da espécie Schinus terebinthifolius Raddi, sugerindo ao extrato da flor da Taraxacum officinale uma maior e melhor ação antibacteriana, anti-inflamatória e anticancerígena.
SOBRECARGA MATERNA FACE AO DIAGNÓSTICO DE TRANSTORNO ESPECTRO AUTISTA E IMPLICAÇÕES PARA A ENFERMAGEM
Authors: BOHN LARISSA , MOLIN ROSSANO SARTORI DAL
Published: September 2023

Objetivo: Avaliar a sobrecarga física e mental de mães de crianças com Transtorno Espectro Autista. Métodos: Configura- se de um estudo, com pesquisa de campo de abordagem quali-quantitativa do tipo exploratório, descritivo e transversal, conduzido com 10 mães de crianças com o diagnóstico de TEA. A pesquisa foi desenvolvida na Associação de Pais e Amigos de Excepcionais de Feliz, Rio Grande do Sul, Brasil. A coleta foi feita em abril de 2023. Para a coleta de dados a técnica empregada foi uma entrevista semiestruturada, que consiste em uma combinação de perguntas abertas e fechadas. O roteiro da entrevista contém 9 perguntas fechadas de caracterização dos participantes e 10 perguntas abertas relacionadas ao cotidiano com a criança autista. Para mensurar os dados quantitativos da sobrecarga materna utilizou-se a escala de Zarit, contendo um total de 22 perguntas fechadas. O estudo foi submetido e aprovado pelo Comitê de Ética em Pesquisa. Resultados: Foi possível identificar um nível moderado a severo de sobrecarga nas mulheres em estudo, conforme a escala de Zarit (1985), podemos associar o fato aos cuidados e exigências que uma criança com diagnóstico de Transtorno Espectro Autista exige. Conclusão: Constatou-se que a sobrecarga de cuidados impacta a saúde física e mental das mães. E está associada a constante necessidade de atenção e suporte muito peculiar que a criança com TEA exige. É uma questão complexa e desafiadora que requer atenção e compreensão dos profissionais enfermeiros e da área da saúde.
PRODUTIVIDADE E QUALIDADE DO TOMATEIRO CULTIVADO COM DIFERENTES SISTEMAS DE CONDUÇÃO: SISTEMAS SUSTENTÁVEIS DE CONDUÇÃO DO TOMATEIRO
Authors: Borges Layane Ferreira , Araújo Dyovana Resende , Fernandes Flávio Lemes , Campos Raiane Fernandes , Fernandes Maria Elisa de Sena , Costa Brenda Lorraine , Moura Carla Lucia Santos , Santana Eidy Jady Fernandez , Lima Maria Luiza Fonseca , Silva Lorraine de Souza
Published: September 2023

Práticas culturais adequadas, como a condução de plantas, densidade de plantio, formas de tutoramento, técnica de aplicação de agrotóxico, cultivares resistentes a pragas e doenças e época de plantio, podem aumentar a produtividade do tomateiro. O objetivo foi avaliar diferentes sistemas de condução do tomateiro em área da Universidade Federal de Viçosa campus Rio Paranaíba em Rio Paranaíba, Minas Gerais, Brasil. O plantio foi realizado 30 dias após a semeadura com o híbrido comercial Forty de tomate. Os tratamentos foram dispostos em delineamento em blocos casualizados, com quatro tratamentos e quatro repetições. Os tratamentos foram quatro tipos de sistema de condução (fitilho, bambu, V20 e V50). A altura e número de folhas e taxa de crescimento (última avaliação de altura de planta menos a primeira) foram avaliadas, em colheitas semanais. O peso de frutos, a produção por planta e total, o comprimento e largura do fruto, espessura da casca. Número de lóculos por fruto e características qualitativas dos frutos como teor de sólidos solúveis e pH foram obtidos. Os dados foram submetidos à análise de variância e as médias comparadas pelo teste de Tukey a p<0,05. O número de folhas foi maior com o sistema V20 e a altura de plantas e taxa de crescimento com o V50. A produção, em toneladas por hectare, foi maior com o sistema V20, o qual é mais vantajoso por aumentar em 32% a produtividade do tomateiro e poder ser utilizado na região do Alto Paranaíba, Minas Gerais, Brasil.
UM SISTEMA DE AUTOMAÇÃO RESIDENCIAL USANDO PLACAS DE DESENVOLVIMENTO
Authors: Batista Juliana Davel , Mestria Mário
Published: September 2023

A comunicação é uma fase importante dos projetos de engenharia. Isso está contido em um processo de revisão sistemática no desenvolvimento do projeto. Além disso, prevê futuras manutenções e desafios para os novos projetos. As formas de comunicação mais utilizadas são o modelo icônico, a forma diagramática, as representações matemáticas e gráficas. Um modelo icônico é definido como instâncias de objetos organizados em um modelo geométrico especificado pelas escalas relativas para várias regiões. Esse modelo serve para ter uma visão peculiar do projeto final. Os projetos de construção estão sendo realizados para reduzir os custos com eletricidade. Os sistemas inteligentes de automação vêm se tornando importantes aliados da eficiência energética, pois são utilizados, por exemplo, para controle de iluminação e climatização. Desta forma, diante da importância da comunicação nos projetos, redução do custo com energia elétrica e novas tecnologias inteligentes de automação, esse trabalho apresenta um sistema de automação residencial. Esse sistema ajuda os engenheiros a prever custos e analisar retroalimentação durante a fase de construção. O sistema pode ser usado para mostrar uma ampla gama de ações para compradores, funcionários, administradores, projetistas e arquitetos e refinar ações futuras.