bluuebunny/crossref_metadata_2025 huggingface dataset:
Die Kraft der Bilder
Authors: Haußmann Annette
Published: June 2021

Bilder sind allgegenwärtig in digitaler Kommunikation, insbesondere in sozialen Medien. Sie fungieren als Gefühls- und Bedeutungsträger, illustrieren und transzendieren die alltägliche Lebenswelt und eröffnen spirituelle Dimensionen. Als Form der Selbstmitteilung und Selbstdarstellung sind sie auch auf persönliche Begegnung angelegt, fördern Emotionsreaktionen und regen interaktive Prozesse an. Insofern generieren sich über statische und bewegte Bilder und die Praxis des Bildteilens neue digitale Gemeinschaften, die das Potenzial zur gegenseitigen Sorge und zum Austausch über Spiritualität und spirituelle Praxis bergen. Diese Prozesse gilt es wahrzunehmen und die Chancen visueller Kommunikation für Spiritual Care und Seelsorge auszuloten.
Pretreatment of diabetic aged rats with combination of ginsenoside-Mc1 and silibinin protects liver from ischemia-reperfusion injury through an AMPK-dependent mechanism
Authors: Wang Hao , Zhu Jiali , Jia Zhe , Lu Sucai
Published: June 2021

Objectives

This study evaluated the protective efficacy of combination treatment with ginsenoside-Mc1 and silibinin against hepatic ischemia-reperfusion (IR) injury in diabetic-aged rats, and further explored AMPK’s role in this protection.

Methods

A high-fat diet/streptozotocin was used to induce type-2 diabetes in aged rats (20–24 months). Diabetic-aged rats were pretreated with ginsenoside-Mc1 (10 mg/kg, IP) and silibinin (50 mg/kg, IP), alone or in combination, for 4 weeks before induction of hepatic IR injury.

Results

Induction of IR injury in diabetic-aged rats significantly elevated plasma levels of hepatic alanine and aspartate aminotransferases and negatively affected liver histology. Levels of 8-isoprostane, ROS production, Bax, and cleaved-caspase-3 expression were higher and manganese-superoxide dismutase (MnSOD), glutathione, and Bcl2 and p-AMPK were lower in IR-receiving group. In comparison to individual treatments, the combination of ginsenoside-Mc1 and silibinin powerfully restored IR-induced changes in liver enzymes and histopathological indices, oxidative markers, AMPK, and apoptotic protein expressions. Inhibition of AMPK using compound-C in H2O2-stimulated HepG2 cells significantly abolished the protective effects of combination treatment.

Conclusions

Combination of ginsenoside-Mc1 and silibinin was superior to their alone usage in protecting hepatocytes of diabetic-aged rats from oxidative/apoptotic damages following IR injury, through an AMPK-mediated mechanism.
Instrument Timbre Enhances Perceptual Segregation in Orchestral Music
Authors: Fischer Manda , Soden Kit , Thoret Etienne , Montrey Marcel , McAdams Stephen
Published: June 2021

Timbre perception and auditory grouping principles can provide a theoretical basis for aspects of orchestration. In Experiment 1, 36 excerpts contained two streams and 12 contained one stream as determined by music analysts. Streams—the perceptual connecting of successive events—comprised either single instruments or blended combinations of instruments from the same or different families. Musicians and nonmusicians rated the degree of segregation perceived in the excerpts. Heterogeneous instrument combinations between streams yielded greater segregation than did homogeneous ones. Experiment 2 presented the individual streams from each two-stream excerpt. Blend ratings on isolated individual streams from the two-stream excerpts did not predict global segregation between streams. In Experiment 3, Experiment 1 excerpts were reorchestrated with only string instruments to determine the relative contribution of timbre to segregation beyond other musical cues. Decreasing timbral differences reduced segregation ratings. Acoustic and score-based descriptors were extracted from the recordings and scores, respectively, to statistically quantify the factors involved in these effects. Instrument family, part crossing, consonance, spectral factors related to timbre, and onset synchrony all played a role, providing evidence of how timbral differences enhance segregation in orchestral music.
Music to Your Ears
Authors: Rathcke Tamara , Falk Simone , Dalla Bella Simone
Published: June 2021

Listeners usually have no difficulties telling the difference between speech and song. Yet when a spoken phrase is repeated several times, they often report a perceptual transformation that turns speech into song. There is a great deal of variability in the perception of the speech-to-song illusion (STS). It may result partly from linguistic properties of spoken phrases and be partly due to the individual processing difference of listeners exposed to STS. To date, existing evidence is insufficient to predict who is most likely to experience the transformation, and which sentences may be more conducive to the transformation once spoken repeatedly. The present study investigates these questions with French and English listeners, testing the hypothesis that the transformation is achieved by means of functional re-evaluation of phrasal prosody during repetition. Such prosodic re-analysis places demands on the phonological structure of sentences and language proficiency of listeners. Two experiments show that STS is facilitated in high-sonority sentences and in listeners’ non-native languages and support the hypothesis that STS involves a switch between musical and linguistic perception modes.
Acute hypoglycemia and risk of cardiac arrhythmias in insulin-treated type 2 diabetes and controls
Authors: Andersen Andreas , Bagger Jonatan I , Baldassarre Maria P A , Christensen Mikkel B , Abelin Kirsten U , Faber Jens , Pedersen-Bjergaard Ulrik , Holst Jens J , Lindhardt Tommi B , Gislason Gunnar , Knop Filip K , Vilsbøll Tina
Published: June 2021

Objective

Hypoglycemia is associated with an increased risk of cardiovascular disease including cardiac arrhythmias. We investigated the effect of hypoglycemia in the setting of acute glycemic fluctuations on cardiac rhythm and cardiac repolarization in insulin-treated patients with type 2 diabetes compared with matched controls without diabetes.

Design

A non-randomized, mechanistic intervention study.

Methods

Insulin-treated patients with type 2 diabetes (n = 21, age (mean ± s.d.): 62.8 ± 6.5 years, BMI: 29.0 ± 4.2 kg/m2, HbA1c: 6.8 ± 0.5% (51.0 ± 5.4 mmol/mol)) and matched controls (n = 21, age: 62.2 ± 8.3 years, BMI 29.2 ± 3.5 kg/m2, HbA1c: 5.3 ± 0.3% (34.3 ± 3.3 mmol/mol)) underwent a sequential hyperglycemic and hypoglycemic clamp with three steady-states of plasma glucose: (i) fasting plasma glucose, (ii) hyperglycemia (fasting plasma glucose +10 mmol/L) and (iii) hyperinsulinemic hypoglycemia (plasma glucose < 3.0 mmol/L). Participants underwent continuous ECG monitoring and blood samples for counterregulatory hormones and plasma potassium were obtained.

Results

Both groups experienced progressively increasing heart rate corrected QT (Fridericia’s formula) interval prolongations during hypoglycemia ((∆mean (95% CI): 31 ms (16, 45) and 39 ms (24, 53) in the group of patients with type 2 diabetes and controls, respectively) with similar increases from baseline at the end of the hypoglycemic phase (P = 0.43). The incidence of ventricular premature beats increased significantly in both groups during hypoglycemia (P = 0.033 and P < 0.0001, respectively). One patient with type 2 diabetes developed atrial fibrillation during recovery from hypoglycemia.

Conclusions

In insulin-treated patients with type 2 diabetes and controls without diabetes, hypoglycemia causes clinically significant and similar increases in cardiac repolarization that might increase vulnerability for serious cardiac arrhythmias and sudden cardiac death.
Adrenal tumors provide insight into the role of cortisol in NK cell activity
Authors: Greenstein Andrew E , Habra Mouhammed Amir , Wadekar Subhagya A , Grauer Andreas
Published: June 2021

Elevated glucocorticoid (GC) activity may limit tumor immune response and immune checkpoint inhibitor (ICI) efficacy. Adrenocortical carcinoma (ACC) provides a unique test case to assess correlates of GC activity, as approximately half of ACC patients exhibit excess GC production (GC+). ACC multi-omics were analyzed to identify molecular consequences of GC+ and assess the rationale for combining the glucocorticoid receptor (GR) antagonist relacorilant with an ICI. GC status, mRNA expression, and DNA mutation and methylation data from 71 adrenal tumors were accessed via The Cancer Genome Atlas. Expression of 858 genes differed significantly between GC− and GC+ ACC cases. KEGG pathway analysis showed higher gene expression of three pathways involved in steroid synthesis and secretion in GC+ cases. Fifteen pathways, most related to NK cells and other immune activity, showed lower expression. Hypomethylation was primarily observed in the steroid synthesis pathways. Tumor-infiltrating CD4+ memory (P = 0.003), CD8+ memory (P < 0.001), and NKT-cells (P = 0.014) were depleted in GC+ cases; tumor-associated neutrophils were enriched (P < 0.001). Given the pronounced differences between GC+ and GC− ACC, the effects of cortisol on NK cells were assessed in vitro (NK cells from human PBMCs stimulated with IL-2 or IL-12/15). Cortisol suppressed, and relacorilant restored, NK cell activation, proliferation, and direct tumor cell killing. Thus, GR antagonism may increase the abundance and function of NK and other immune cells in the tumor microenvironment, promoting immune response in GC+ ACC and other malignancies with GC+. This hypothesis will be tested in a phase 1 trial of relacorilant + ICI.
Intralipid therapy and adverse reproductive outcome: is there any evidence?
Authors: Kumar Parijot , Marron Kevin , Harrity Conor
Published: June 2021

Controversy exists regarding the benefits of intravenous intralipid therapy in patients with a poor reproductive history. It is frequently reported that there is no evidence to support the effectiveness, utility or safety for this treatment. While individual studies may be perceived as weak, a systematic review and meta-analysis were performed to determine if there is any advantage to patients. PubMed, Embase and Scopus searches were performed with the target populations being either recurrent pregnancy loss (RPL), or recurrent implantation failure (RIF) undergoing assisted reproductive technology (ART) and receiving intralipid infusions. These cohorts were compared with either placebo, no intervention or alternative treatments. The most relevant outcome measures were considered to be clinical pregnancy rate (CPR), live birth rate (LBR), implantation rate (IR) and miscarriage rate (MR). Twelve studies encompassing 2676 participants met the criteria for selection and were included and reviewed. Treatment of the target population with intralipid led to an improvement in IR (Odds Ratio (OR): 2.97, 2.05–4.29), pregnancy rate (OR: 1.64, 1.31–2.04), and LBR (OR: 2.36, 1.75–3.17), with a reduction in MR (OR: 0.2, 0.14–0.30). Although intravenous intralipid is not recommended as a routine treatment for recurrent miscarriage or implantation failure, there is enough data to suggest consideration in selected patients where routine testing is unremarkable, standard treatments have failed and immunological risk factors are present. The presence of abnormal uterine natural killer (uNK) cells needs more study as a target marker to determine those who could benefit.

Lay summary

There is controversy regarding the benefits and efficacy of intravenous intralipid therapy in patients with a poor reproductive history. It is frequently reported that there is no credible evidence to support their use. A situation we frequently face as medical professionals is patients asking us to consider immune therapy (such as intralipid) for reproductive failure where good quality embryos have been used. Intralipid infusions have been reported to improve pregnancy rates with IVF, and reduce the miscarriage risk in selected patient groups, but study results are not universally accepted. We have performed a detailed review and analysis of the literature to determine if there is any benefit to this immune treatment in specific patient groups. Our paper identified and analyzed 12 studies, finding that treatment with intravenous intralipid leads to an improvement in implantation, pregnancy and live birth rates, with a decrease in miscarriage rate. This study shows that there is evidence to suggest consideration of intralipid in certain patients where standard treatments have failed.
An Initiative to Decrease Laboratory Testing in a NICU
Authors: Klunk Christopher J. , Barrett Renee E. , Peterec Steven M. , Blythe Eleanor , Brockett Renee , Kenney Marta , Natusch Amber , Thursland Caitlin , Gallagher Patrick G. , Pando Richard , Bizzarro Matthew J.
Published: June 2021

BACKGROUND AND OBJECTIVES

Laboratory testing is performed frequently in the NICU. Unnecessary tests can result in increased costs, blood loss, and pain, which can increase the risk of long-term growth and neurodevelopmental impairment. Our aim was to decrease routine screening laboratory testing in all infants admitted to our NICU by 20% over a 24-month period.

METHODS

We designed and implemented a multifaceted quality improvement project using the Institute for Healthcare Improvement’s Model for Improvement. Baseline data were reviewed and analyzed to prioritize order of interventions. The primary outcome measure was number of laboratory tests performed per 1000 patient days. Secondary outcome measures included number of blood glucose and serum bilirubin tests per 1000 patient days, blood volume removed per 1000 patient days, and cost. Extreme laboratory values were tracked and reviewed as balancing measures. Statistical process control charts were used to track measures over time.

RESULTS

Over a 24-month period, we achieved a 26.8% decrease in laboratory tests performed per 1000 patient days (∽51 000 fewer tests). We observed significant decreases in all secondary measures, including a decrease of almost 8 L of blood drawn and a savings of $258 000. No extreme laboratory values were deemed attributable to the interventions. Improvement was sustained for an additional 7 months.

CONCLUSIONS

Targeted interventions, including guideline development, dashboard creation and distribution, electronic medical record optimization, and expansion of noninvasive and point-of-care testing resulted in a significant and sustained reduction in laboratory testing without notable adverse effects.
Quality variation of fruits of species of the genus Lycium in Ukraine: A comparative morphological analysis
Authors: Zhurba M. Y. , Klymenko S. V. , Szot I.
Published: June 2021

Goji berries (Lycium L.) have been an important element of traditional Chinese medicine for centuries due to their health-promoting properties and chemical composition, and they deserve the term “superfruit”. The objective of this study was to evaluate the morphological parameters of Lycium (L. barbarum L., L. chinense Mill. and L. truncatum Y. C. Wang) fruits for 21 cultivars and varieties from the collections in the M. M. Gryshko National Botanical Garden of NAS of Ukraine (Kyiv). Cultivars and varieties differed by weight, shape, and size of fruits. Their morphometric parameters were the following: fruit weight from 0.44 (L. truncatum cv. Princess Tao) to 1.08 (L. chinense cv. Tybet) g, fruit length from 10.41 (L. chinense cv. Delikat) to 22.84 (L. truncatum cv. Super Sweet) mm, fruit diameter from 7.16 (L. truncatum cv. Princess Tao) to 13.48 (L. chinense cv. Delikat) mm, number of seeds in fruit from 1.0 to 49.0. The shape indexes of fruits were found ranging from 0.78 (L. chinense cv. Delikat) to 2.56 (L. truncatum cv. New Big). The analysis of coefficient of variation showed the difference of variability in morphometric characteristics between Lycium spp. cultivars and varieties. The most variable features are fruit weight (11.4–37.1%) and number of seeds in fruits (9.7–60.8%), which are important parameters for selection that indicates about potential success of selection. Using the cluster analysis with the Bray-Curtis similarity index allowed us to establish the relationships among the fruits Lycium spp. germplasm and arrange the cultivars and varieties into three relatively main clusters. Plants of the genus Lycium, due to the growing importance as functional food, require systematic research work. In cases of food use, large fruit size is important. In the results of our research on L. barbarum, L. chinense and L. truncatum, in terms of fruit sizes the following cultivars and varieties stand out : LB02, LC Amber Sweet and LT Super Sweet. The collected varieties can be the basis for obtaining new cultivars distinguished by the size of crops and their quality.
Structural features of the mesonephros of semianadromous fish on the example of the European smelt (Osmerus eperlanus)
Authors: Flerova E. A.
Published: June 2021

At present, special attention is drawn to the study of the adaptation of aquatic organisms to a complex of environmental factors precisely at the cellular level. It is very important to study the structural and functional features of the kidney, which not only plays a key role in osmoregulation, but also makes a significant contribution to maintaining homeostasis at the level of functioning of a single nonspecific defense system of the body. In this aspect, the study of species belonging to a unique ancient group, united in the order salmoniformes, is highly relevant. Using the methods of light and electron microscopy, we investigated the morphology and ultrastructure of the mesonephros of the population of the semianadromous ecological form European smelt Osmerus eperlanus inhabiting the Gulf of Finland of the Baltic Sea and performing spawning migrations in the Luga River of the Leningrad Region. The general scheme of the trunk kidney organization is given, the structural features and the ratio of leukocytes and structures of the smelt nephron are revealed. It is shown that the development of hematopoietic tissue in the mesonephros, the number of mature forms of granulocytes are systematic signs which do not depend on the ecology of the species. The ratio of leukocytes, the width of the cisterns of the rough endoplasmic reticulum of plasma cells, the structure and number of granules in granulocytes are associated with the peculiarities of the functioning of the cellular link of the immune system under certain conditions of the species habitat. The ultrafine structure of the ion-transporting interstitial cells, as well as the ultrastructural features found in the smelt nephron, can be considered cytological markers of smelt adaptation to a semianadromous lifestyle.
Morphological identification of Nematodirus spathiger nematodes (Nematoda, Molineidae) obtained from the small intestine of sheep
Authors: Melnychuk V. , Yevstafieva V. , Pishchalenko M. , Reshetylo O. , Antipov A.
Published: June 2021

Strongyloidiases are caused by nematodes of the suborder Strongylida and are the most widely prevalent group of gastrointestinal helminthiases of sheep in many regions of the world. Among gastrointestinal strongylids, the helminths of the genus Nematodirus are represented by the largest number of species and highest infection rates in sheep. Nematodirosis causes significant economic losses in the sheep industry through decreased sheep productivity, delayed growth and development of young animals, and a reduced resistance to other diseases. Timely and accurate diagnosis of nematodirosis and identification of the pathogen will effectively prevent the disease and help to carry out treatment and prevention measures. Therefore, the aim of the work was to study the definitive morphometric characters of mature males and females of Nematodirus spathiger Railliet, 1896, obtained from the small intestine of domestic sheep. The results of experimental studies showed that nematodes of this species morphologically are characterized by a thin filiform body, a vesicle at the head end and a chitinous tooth in a short oral capsule. The differential morphological features of male nematodes of N. spathiger include specifics of the structure of spicules, their distal end and the shape and location of the rays of the caudal bursa; in females, those are the features of the structure of the vulva and tail end. In identification of male nematodes of N. spathiger, it is proposed to use 40 metric parameters, of which 11 characterize the overall size of the body, esophagus and vesicles, 24 refer to the size of the tail bursa, 5 to the size of the spicules and the enveloping membrane. To help identify the females of N. spathiger, 25 parameters are chosen, of which 14 also characterize the overall size of the body, esophagus and head vesicle, 6 refer to the size of the cuticular formations of the vulva and its location, and 5 to the size of the tail end, the location of the anus and the size of the tail spike.
The influence of microwave electromagnetic radiation on rat heart morphogenesis during thyroidectomy
Authors: Drobakhin O. O. , Magro V. I. , Kosharnyi V. V. , Rutgaizer V. H. , Abdul-Ohly L. V.
Published: June 2021

It is known that electromagnetic radiation affects the functional systems of living beings, in particular, the endocrine and cardiovascular systems and directly the heart cells and their functioning. In this case, the influence of electromagnetic radiation significantly affects the properties of the cardiovascular system and changes physiological processes in it. Moreover, sensitivity to signals is higher for biosystems with a higher level of organization. The method of simulating hypothyroidism for rats makes it possible to develop an experimental model for analyzing morphogenetic changes in the rat heart. Under conditions of hypothyroidism modeling, destructive changes in muscle fibers are observed in the myocardium after thyroidectomy, but after microwave irradiation with an exposure of 45 minutes, a regenerative-compensatory reconstruction of the structural components of the myocardium of the heart wall occurs. After thyroidectomy and microwave irradiation with an exposure of 120 minutes, an increase in degenerative and destructive processes in the heart myocardium was observed. For the first time, a comparative ultramicroscopic study using electron microscopy was carried out. It showed that after electromagnetic irradiation with an exposure of 45 minutes, the general structure of the mitochondrial apparatus does not change. Irradiation with an exposure of 120 minutes causes the destruction of subsarcolemal and paranuclear organelles, edema and degradation of intermyofibrillar mitochondria. After exposure to electromagnetic radiation with the exposure of 45 minutes in a hypothyroid state, a compensatory restructuring of the energy apparatus of the contractile cardiomyocytes of the left ventricle occurs due to the formation of mitochondria and an increase in their contact interaction. After exposure to radiation for 120 minutes, the development of destructive-degenerative processes in the mitochondrial apparatus of left ventricular cardiomyocytes, deepening of damage to intermitochondrial contacts was observed. The most significant increase in the relative volume of the endothelium in the areas of the rat heart myocardium was observed for the case of microwave irradiation only (without experimental hypothyroidism) with exposure duration of 45 minutes. Immunohistochemical study both for the case of microwave irradiation only and for the case of microwave irradiation under conditions of experimental hypothyroidism allows us to conclude that morphogenetic transformations are highly active in the myocardium of the heart when the duration of exposure is 45 minutes. This study will make it possible to develop recommendations for persons with thyroid diseases on the duration of daily exposure of staying in electromagnetic field emitted by devices with characteristics similar to the case under study.
Features of modern winter wheat varieties in terms of winter hardiness components under conditions of Ukrainian Forest-Steppe
Authors: Pirych A. V. , Yurchenko T. V. , Hudzenko V. M. , Demydov O. A. , Kovalyshyna H. M. , Humeniuk O. V. , Kyrylenko V. V.
Published: June 2021

In recent years, there has been a significant change in climatic conditions affecting the cultivation and yield of winter wheat. Therefore, the creation of wheat varieties with high adaptive potential is one of the main tasks of modern breeding. A significant component of the overall adaptive potential of winter wheat is winter hardiness, which is determined by a set of characters enabling plants to overwinter. To a large extent, winter hardiness is determined by gene systems that control vernalization requirement duration, photoperiod reaction, and frost resistance. The research is aimed at determining the features of modern winter wheat varieties developed at the V. M. Remeslo Myronivka Institute of Wheat of the National Academy of Agrarian Sciences of Ukraine in terms of winter hardiness components and adaptive potential in the environment of the Central part of the Ukrainian Forest-Steppe. Winter bread wheat varieties Estafeta myronivska, Hratsiia myronivska, MIP Assol, and Balada myronivska were studied. They also were crossed on incomplete diallele scheme with three near-isogenic lines derived from Erythrospermum 604 with different alleles of Vrd genes 1) Vrd1Vrd1vrd2vrd2, 2) vrd1vrd1Vrd2Vrd2, and 3) vrd1vrd1vrd2vrd2. It was established that vernalization requirement duration in the varieties Estafeta myronivska and Balada myronivska was short whereas in the varieties Hratsiia myronivska and MIP Assol it was medium. All the varieties studied have medium photoperiod sensitivity. The results of the hybridological analysis indicate the absence of the Vrd1 and Vrd2 genes in the varieties. Frost tolerance of these varieties is at the same level and higher than in the highly tolerant to the low temperatures variety Myronivska 808. Thus, the results indicate the possibility of recombining different levels of expression of these traits in genotypes by breeding efforts. This has great practical importance in farming, because in recent years the areas of crops harvested late (corn, sunflower, etc.) in the production conditions has significantly increased. It causes a shift in sowing dates of winter wheat to a later period. In this case, varieties Estafeta myronivska, Hratsiia myronivska, MIP Assol, and Balada myronivska are able to undergo sufficient hardening, to satisfy the vernalization requirement, and to form a high level of winter hardiness. Their relatively medium photoperiod sensitivity allows vegetation to be restored a little earlier in the spring and winter reserves of moisture to be used more effectively.
«После признания и торжества национального начала многие общечеловеческие вопросы разрешаются»: европейский опыт и российский национальный проект в работах А. Д. Градовского.
Authors: Венгер Наталья Викторовна
Published: June 2021

The purpose of the article is to study the researches by A. Gradovsky, dedicated to the problem of nationalism as a phenomenon that manifested itself in the 19th century Western Europe. The author studies how the scholar correlated the above-named phenomena with the situation in the Russian Empire. N. Venger has found out the place of Gradovsky in the context of the general polemic about the Russian national project. Being rather a scholar, teacher and observer than a politician and publicist, Gradovsky reflected the European experience through the prism of the Russian Empire`s history. His Eurocentricity was important due to the fact that the dominant conservative ideology had rejected the western pattern of development for a long time. Most of Gradovsky's articles on national issues were created in the 1870s – at the beginning of 1880s. The scholar was never able to propose a global national project for the Russian Empire. However, projecting European phenomena onto the Russian Empire`s future development, Gradovsky paid attention to the most painful points of the society, which impede the progress of the national project`s formation and required reforms. The author created his own concept of ethnicity and nation, discussed the issue of the language unification and state religion role as well as advocated freedom of conscience. The topics of serfdom remnants overcoming, the elimination of estates, the emancipation of the peasantry were of great importance for the scholar. Gradovsky also touched on the problem of choosing Russia`s national idea, which he associated with Slavism. Supporting decisive actions in Polish uprising suppressing, Gradovsky insisted on keeping a dialogue with the Poles. While solving the German question, he demanded to avoid Russian xenophobia regarding the Russian Germans. It was not clear what the scholar thought about the possibility to create a national state from the totally heterogeneous Russian empire.
Рецензія на книгу Т. М. Чернової-Дьоке «Німецькі поселення на Північному Кавказі Російської імперії».
Authors: Бобилєва Світлана Йосипівна
Published: June 2021

The review provides an analysis of the monograph by T. N. Chernova-Dyoke, dedicated to the history of the formation, development and disappearance of the German-speaking colonies in the North Caucasus. The events till 1941(including deportation) are being studied.
A prediction model of mining subsidence in thick loose layer based on probability integral model
Authors: Li Jingxian , Yu Xuexiang , Liang Ya
Published: June 2021

The probability integral method is the most commonly used mining subsidence prediction model, but it is only applicable to ordinary geological mining conditions. When the loose layer in the geological mining conditions where the mining face is located is too thick, many inaccurate phenomena will occur when the movement deformation value is predicted by the probability integral method. The most obvious one is the problem that the predicted value converges too fast compared with the measured value in the edge of the sinking basin. In 2012, Wang and Deng proposed a modified model of probability integral method for the marginal errors in the model of probability integral method and verified the feasibility of the method through examples. In this paper, the method is applied to the prediction of surface movement under thick and loose layers after modified. Through practical application, it is found that due to the angle between the working face and the horizontal direction, the average mining depth in the strike direction is different from the average mining depth in the inclined direction, and the main influence radius of the two main sections are often. Therefore, based on this problem, this paper divides the main influence radius into trend and tendency and adjusts the parameters in the model to find the rules of the parameters. The original method uses a dynamic scale factor to adjust the predicted shape of the graph by adjusting the sinking coefficient. This study is aimed to set the scale factor to 0.5 and fix the value of the sinking factor, and propose to adjust the integral range and then adjust the shape of the graph to make it more in line with the actual measurement situation.
Study on the Evolution Monitoring of Topographic and Hydrological Characteristics of Small Watershed Based on Remote Sensing and GIS
Authors: Pan Hong , Khabazi Mostafa
Published: June 2021

Soil and water conservation is one of the key measures to improve the ecological environment of small watersheds and maintain the healthy life of the region. With the current method used to monitor the evolution of topographic and hydrological characteristics of a small watershed, the edge keeping index of the image and the signal-to-noise ratio of the image are low, the monitoring results are inaccurate, and there are some problems such as low edge keeping ability, poor denoising effect, and low monitoring accuracy. A monitoring method based on remote sensing and GIS for the evolution of topographic and hydrological characteristics of small watersheds is proposed. The hyperspectral data was transformed by the Principal Component Analysis (PCA). Group principal component images, use sparse representation method based on adaptive dictionary and dual-tree complex wavelet transform method to denoise principal component images with a small amount of information were the objectives of the paper; also the use the multi-scale wavelet transform to detect image edge; build a binary model of a pixel, extract vegetation index, and terrain factor based on a binary model of the pixel, and realize terrain and hydrological characteristics of the small watershed. The experimental results show that the proposed method has the high edge-preserving ability, good denoising effect, and high monitoring accuracy.
Priapismo en paciente en diálisis y con COVID-19. Reporte de caso
Authors: Larrarte-Arenas Carolina , Vargas-Ángel Diana Carolina
Published: June 2021

Introducción. El priapismo es una condición infrecuente en pacientes en diálisis que se puede presentar por factores inherentes a esta terapia y a la enfermedad renal. Por otra parte, es una entidad que se ha reportado en pacientes con síntomas severos de COVID-19 y se ha asociado a coagulopatía secundaria a la infección, pero de la que no hay registro en casos leves de esta enfermedad.
Presentación de caso. Paciente masculino de 65 años en hemodiálisis y con infección por SARS-CoV-2 con síntomas leves, quien consultó al servicio de urgencias de un hospital de cuarto nivel por erección peneana dolorosa de 30 horas de evolución. Al examen físico se evidenció la erección, sin otros hallazgos relevantes. Con base en la historia clínica, el examen físico y los resultados de laboratorio, se diagnosticó priapismo isquémico y se realizó drenaje de senos cavernosos y aplicación de dos inyecciones de epinefrina (cada una con una dosis de 2mL de solución de epinefrina 1/100 000), lográndose resolución completa de la condición.
Conclusiones. Hasta el momento de la elaboración del presente reporte de caso no hay información disponible de casos de priapismo en pacientes con manifestaciones leves de COVID-19, y tampoco hay claridad de cómo se debe evaluar el riesgo de trombosis en este grupo de pacientes. Desde el punto de vista fisiopatológico, factores relacionados con la diálisis y la enfermedad renal pudieron predisponer a este paciente al priapismo, aunque no es claro el rol de la infección por SARS-CoV-2. Por tanto, se requieren estudios que permitan confirmar o descartar la asociación entre COVID-19 y priapismo en pacientes en diálisis.
Motivación por el aprendizaje, un aspecto fundamental en la formación de estudiantes de ciencias de la salud durante la pandemia por COVID-19
Authors: Muñoz-Vidal Fabián Andrés , Beltrán Véliz Juan Carlos
Published: June 2021

Señor editor:
La pandemia por el nuevo coronavirus SARS-CoV-2 y la enfermedad que causa (COVID-19) ha generado una crisis de salud sin precedentes a nivel mundial. Tal ha sido el impacto de la COVID-19 que diferentes sectores se han visto perjudicados, como por ejemplo la educación superior, cuyas instituciones han tenido que suspender temporalmente muchas de sus actividades afectando a cerca de 165 millones de estudiantes solo en Latinoamérica y el Caribe,1 esto obedeciendo a las medidas de inmovilización social y aislamiento obligatorio que fueron instauradas por las autoridades de salud como estrategias para disminuir la expansión del virus.
Juventude
Authors: Beleza Joana
Published: June 2021

Pereira, Cláudia (Org.). Brazilian Youth: Global Trends and Local Perspectives. New York: Routledge, 2020..
Zakir Naik’s Concept of Divinity-Cosmology: Criticism-Reconstruction of the Modern Natural-Cosmological Theology
Authors: Saputra Gigih
Published: June 2021

Zakir Naik voices the evidence of God’s existence by employing the Big Bang Theory while proving the truth of al-Qur’ān. His positive reputation and controversy also create an impact on his da’wa journey. This study aims to bring out criticism and reconstruction on the concept of Zakir Naik’s cosmology and argument of God’s existence. The author, therefore, uses the Big Bang theory, al-Kindī’s Natural Theology, and Peter Kreeft’s Kalam Cosmology Argument. The result of the research shows the irrelevance of Zakir Naik’s explanations to the Big Bang theory itself, in addition to his lack of exposition about the theory. His idea, in fact, only centers around the proof of God’s existence as well as the truth of al-Qur’ān. Philosophically, this suggests that his concept of creation is inadequate. This, moreover, indicates that the explanation of the infinity of causality and the Infinite Regress critiques are too classic. The article attempts to reconstruct the Big Bang Theory to be more pertinent and profound and also to reform atheism cosmology. The attempt includes strengthening the position of Creatio ex Nihilo based on al-Kindī’s Natural Theology and its comparison to the other theory, such as Emanationism. Additionally, it is to extend the argument of causality and the criticisms toward Infinite Regression with the argumentation development based on al-Kindi’s Theology and Peter Kreeft’s Kalam Cosmology.
When Abangan Embraces Sufism: Religious Phenomenology to Counter Radicalism in Contemporary Java
Authors: Nurish Amanah
Published: June 2021

Abangan is one of the socio-religious groups regarded as a marginal community among the trichotomy of santri and priayi. It has been known that abangan were not religious Muslim, and they are poor farmers as well as workers, backward and less educated people. Meanwhile, santri are more religious and priayi among Javanese society are middle-class people practising syncretic Islam. The thesis on “The Religion of Java,” by Clifford Geertz, was more than a half-century indicated religious and social classification in Javanese society. In the midst of political polarization of Indonesian reformation, transnational Islamic groups began to establish their movement widely. Transnational Islamic groups that promote radicalism and violent extremism clearly avoid local wisdom and mysticism. As a result, abangan has experienced dramatic religious and social change. This study aims to see how to face radicalism after reformation in the social and religious transformation of abangan in Java. Previous studies have shown that the phenomenon of radicalism affects religious intolerance addressed to minority groups like abangan. This research paper aims to examine how abangan reacts to radicalism and engages with Sufism and their devotion to tarekat. Abangan recently appears to convert and join the tarekat movement as an alternative discourse to encounter modernism and religious radicalism.
Elliptic curve involving subfamilies of rank at least 5 over $\mathbb{Q}(t)$ or $\mathbb{Q}(t,k)$
Authors: YOUMBAI Ahmed El Amine , ULUDAĞ A. Muhammed , BEHLOUL Djilali
Published: June 2021

Motivated by the work of Zargar and Zamani, we introduce a family of elliptic curves containing several one- (respectively two-) parameter subfamilies of high rank over the function field $\mathbb{Q}(t)$ (respectively $\mathbb{Q}(t,k)$). Following the approach of Moody, we construct two subfamilies of infinitely many elliptic curves of rank at least 5 over $\mathbb{Q}(t,k)$. Secondly, we deduce two other subfamilies of this family, induced by the edges of a rational cuboid containing five independent $\mathbb{Q}(t)$-rational points. Finally, we give a new subfamily induced by Diophantine triples with rank at least 5 over $\mathbb{Q}(t)$. By specialization, we obtain some specific examples of elliptic curves over $\mathbb{Q}$ with a high rank (8, 9, 10 and 11).
Influence of Anthropogenic Factors on the State of Woody Plants in Volgograd
Authors: Tereshchenko Tatyana , Sroslova Galina , Postnova Margarita , Zimina Yuliya , Sroslov Mikhail
Published: June 2021

Studies conducted in different cities have shown that trees growing in urbanized areas reduce noise levels and cleanse the air of solid particles, ozone, sulfur dioxide, carbon monoxide, nitric oxide and other pollutants contained in car fumes, transport dust and generated by industry. The reaction to the influence of negative factors in woody plants is in disturbances in metabolism and biochemical composition, their general development also changes, and their population decreases. The indicators of disorders occurring at the cellular and tissue levels are more sensitive to the influence of negative anthropogenic factors in comparison with external manifestations. The research was carried out on woody plants: small-leaved linden (L. Tíliacordáta), horse chestnut (L. Aésculus); the soil. The research was carried out in 9 districts of Volgograd. The assessment of the state of woody plants was carried out by the visual method based on external signs. GOST methods were used to determine the concentrations of chemical elements in the foliage and soil of woody plants. Using physical and chemical methods, the concentrations of chemical elements in the soil and biomass of woody plants taken from the selected areas of the city of Volgograd were obtained, and the correlation between these indicators and the life state of woody plants was determined. The dependence of the indicators of the concentration of nutrients in the soil and the state and viability of woody plants was well traced. In general, the state of most of the woody plants of the city was healthy or moderately weakened. Such a high level of the life state is explained by the relatively young age structure of the studied plants, because at a young age woody plants are more resistant to negative factors of the urban environment. The revealed features of the life of woody plants in the city can be taken into account in the practice of city green building.
Self-care among people with Diabetes Mellitus and quality of care in Primary Health Care
Authors: Suplici Samara Eliane Rabelo , Meirelles Betina Hörner Schlindwein , Lacerda Josimari Telino de , Silva Denise Maria Guerreiro Vieira da
Published: June 2021

ABSTRACT Objectives: to verify the adherence to self-care activities among people with diabetes mellitus and its association with quality of care received in Primary Care. Methods: a cross-sectional study with 329 people with diabetes assisted in Primary Care. Sociodemographic and self-care data were collected. To assess quality of care in Primary Care, secondary data from the Access and Quality Improvement Program were used. For comparisons between adherence to self-care activities and quality of care received in Primary Care, the Kruskal-Wallis Test was used. Results: better adherence to the diet, blood glucose monitoring and medication use were observed among people with diabetes treated in Primary Care with better coordination of care, agenda organization, and equipment. Foot examination, despite the inverse relationship with quality of care, proved to be desirable. Conclusions: adherence to self-care among people with diabetes was associated with quality of care received in Primary Care.
Association between early pregnant hospitalization and use of obstetric interventions and cesarean: a cross-sectional study
Authors: Terto Tamara Lopes , Silva Thales Philipe Rodrigues da , Viana Thamara Gabriela Fernandes , Sousa Ana Maria Magalhães , Martins Eunice Francisca , Souza Kleyde Ventura de , Matozinhos Fernanda Penido
Published: June 2021

ABSTRACT Objective: Evaluate the association between early pregnant hospitalization and the use of obstetric interventions and cesarean delivery route. Methods: Cross-sectional study, with 758 women selected at the time of childbirth. It was assumed as early hospitalization when the woman was admitted to the hospital having less than 6 cm of cervical dilation. Logistic regression models were constructed in order to estimate the odds ratio for each obstetric intervention, adjusted by sociodemographic and obstetric variables. Results: 73.22% of women were early hospitalized. On average, they had 1.97 times the chance to undergo Kristeller’s maneuver, 2.59 and 1.80 times the chance to receive oxytocin infusion and analgesia, respectively, and 8 times more chances to having their children by cesarean delivery when compared to women that had timely hospitalization. Conclusion: Early hospitalized women were submitted to a higher number of obstetric intervention and had increased chances of undergoing cesarean sections.
Gender violence against woman nursing students: a cross-sectional study
Authors: Silva Luiza Csordas Peixinho da , Hino Paula , Oliveira Rebeca Nunes Guedes de , Fernandes Hugo
Published: June 2021

ABSTRACT Objective: to identify the sociodemographic profile of nursing students who suffered gender violence and to know the characteristics of the violence that occurred in this population. Method: a cross-sectional study with 91 nursing students from a public university in southeastern Brazil, between September 2019 and January 2020. A sociodemographic questionnaire and the World Health Organization Violence Against Women, section 10 were used. Results: approximately 65% suffered some form of gender violence during their lifetime, mainly perpetrated by family members. 41.7% were victims of physical aggression, 23% suffered sexual harassment, 30.8% suffered sexual abuse. There was a pattern of intergenerational violence (p<0.001), vulnerability of self-declared lesbians and/or bisexuals (p=0.705), Christian or evangelical (p<0.001). Conclusion: gender violence was high among those surveyed. The experience of forms of violence can damage students’ lives. There is a need for attention from teaching institutions and professors in addressing the theme.
Epidemiological profile of women with gynecological cancer in brachytherapy: a cross-sectional study
Authors: Rosa Luciana Martins da , Hames Maria Eduarda , Dias Mirella , Miranda Gisele Martins , Bagio Camila Beltrame , Santos Maristela Jeci dos , Kalinke Luciana Puchalski
Published: June 2021

ABSTRACT Objective: to analyze the sociodemographic and clinical profile of women with gynecological cancer in brachytherapy. Method: a cross-sectional study including records of 1,930 visits of women in brachytherapy assisted between 2006-2016 in Santa Catarina (Brazil). Collection was performed in 2019, in an institutional bank, submitted to frequency measurements, chi-square test, 95% confidence intervals, significance level of 0.05. Results: women aged 40-59 years (47.2%), white (93.3%); with elementary school (65%); cervical cancer (78.5%); stages II-III (73.3%) figured prominently. In the comparison of staging proportions in the topography variable, a higher proportion of malignant neoplasm of cervix uteri unspecified in the grouped III-IV staging (84.6%). Conclusion: the profile analysis shows the need for screening and health education for prevention and/or early detection of gynecological cancers and training of nurses specialized in radiotherapy to care for women’s health.
Integrated Care model: Transition from acute to chronic care
Authors: Ghiyasvandian Shahrzad , Shahsavari Hooman , Matourypour Pegah , Golestannejad Mohamad Reza
Published: June 2021

ABSTRACT Objective: Description and discussion dimensions of Integrated Care Model. Methods: A descriptive study is done that describe a technological innovation, intervention strategies for professional performance. Results: Integrated Care Model (ICM) has two main categories include individual and Group-and disease-specific Model. First, is used for risky patients or with comorbidities. In second category; Chronic Care Model (CCM) is common form of Integrated Care Model to improve resultants in the patients with chronic condition, to move from acute care to integrate, regular, long-lasting, preventative and community-based nursing. Final considerations: It is important to consider patient as an active member of the treatment team. It seems to be essential to monitor performance of care system. On the other hand, offer multidisciplinary care leads to present desirable care, tailored to the specific needs of patients regarding safety, patient-centered care and their culture.