bluuebunny/crossref_metadata_2025 huggingface dataset:
The effect of tranexamic acid on blood loss in non-urgent trauma patients undergoing major orthopaedic surgery: A retrospective cohort study
Authors:   Faculty of Medicine, University of Crete, Heraklion, Crete, Greece., Nyktari Vasileia , Diamantaki Helen ,   Department of Anaesthesiology, University Hospital of Heraklion, Crete, Greece., Stefanakis Georgios ,   Department of Anaesthesiology, University Hospital of Heraklion, Crete, Greece., Koutoulaki Emmanouela ,   Department of Anaesthesiology, University Hospital of Heraklion, Crete, Greece., Vasilos Periklis ,   Department of Anaesthesiology, University Hospital of Heraklion, Crete, Greece., Alegakis Athanasios ,   Faculty of Medicine, University of Crete, Heraklion, Crete, Greece., Sperelakis Ioannis ,   Department of Trauma and Orthopedic Surgery, University Hospital of Heraklion, Crete, Greece., Papaioannou Alexandra ,   Faculty of Medicine, University of Crete, Heraklion, Crete, Greece.
Published: January 2022

Objectives: This study aims to clarify the role of prophylactic TXA on blood loss and transfusion requirements in a subgroup of trauma patients undergoing major orthopaedic surgery on a non-urgent basis. Study design: This is a retrospective cohort study Setting: Tertiary University Hospital of Crete (2017-2018) Patients/participants: Polytrauma patients who underwent delayed major orthopaedic surgery Main outcome measurement: Significant haemorrhage occurrence in relation to TXA administration. In a subgroup of patients Rotational Thromboelastometry (ROTEM) was used to reveal their haemostatic profile prior to TXA administration. Methods: Data from anaesthetic and ICU records were analyzed regarding age, sex, body mass index, ASA physical status, Injury Severity Score, Caprini Score, intraoperative blood loss, number of packed red blood cells units transfused, volume of crystalloids administered, operation duration, preoperative and postoperative haemoglobin values, and days from hospital admission to surgery. ROTEM analysis in a subgroup of patients revealed their haemostatic profile prior to TXA administration. Results: Twenty five out of 46 patients received prophylactic TXA treatment. After adjustment for confounding factors, the odds ratio for the composite endpoint for prophylactic TXA (n=25) vs no TXA (n=21) was 1.27 (95% confidence interval, CI 0.39-4.16). Propensity matched analysis confirmed the absence of a difference between patients with and without TXA. In all patients analyzed with ROTEM normal or hypercoagulable status was revealed. Conclusions: In trauma patients undergoing major orthopaedic surgery more than 12 hours after the initial injury, TXA has no effect on blood loss and transfusion requirements. Keywords: tranexamic acid; blood loss; transfusion; orthopaedic trauma surgery; spine surgery; pelvis surgery; significant bleeding in orthopaedic surgery
Lofgren’s syndrome: A case report and review of the literature
Authors:   Department of Endocrinology and Metabolism, the Affiliated Hospital of Qingdao University, Qingdao, 266003, China., Bingzi Dong , Qian Zhao ,   Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Qingdao University, Qingdao, 266003, China., Mei Wang ,   Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Qingdao University, Qingdao, 266003, China., Jinfeng Li ,   Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Qingdao University, Qingdao, 266003, China., Lina Wang ,   Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Qingdao University, Qingdao, 266003, China., Chunhua Du ,   Department of Respiratory and Critical Care Medicine, the Affiliated Hospital of Qingdao University, Qingdao, 266003, China.
Published: January 2022

Lofgren’s syndrome is a variant of acute-onset sarcoidosis, characterized as Hilar Lymphadenopathy (HL), Erythema Nodosum (EN) and bilateral arthritis or arthralgia, with elevated serum Angiotensin Converting Enzyme (ACE) and calcium level. It is relatively common in Caucasians, but rarely reported in Asian countries. We reported a 72-year old Chinese female with HL, acute onset EN, multiple arthritis and arthralgia, and achieved remission with prednisolone treatment. We summarized reported cases in European and Asia countries, and investigated the characteristics of etiology, genetics, prognosis and therapeutic strategy variants due to different ethnicities. Almost all the patients showed HL, and half of them exhibited classical triad. ACE, the biomarker of Lofgren’s syndrome, elevated in more than half of the European cases, but only 30% in Asian patients. NASID is considered as the first choice of Lofgren’s syndrome, and glucocorticoid may be necessary in severe cases. One quarter of the cases from European countries need steroid therapy. However, the proportion is much higher (64.3%) to achieve symptomatic relief. Considering Lofgren’s syndrome is rare and less recognized from sarcoidosis in Asian patients, further investigation is needed to achieve clinical experience. Keywords: lofgren’s syndrome; lymphadenopathy; erythema nodosum; arthritis; sarcoidosis.
Congenital nephrogenic diabetes insipidus and the trauma injured brain: A case report
Authors:   Department of Anaesthesiology and Critical Care, Stellenbosch University, South Africa., Davids Ryan , Ahmed Nadiya ,   Department of Surgical Sciences, Stellenbosch University, South Africa., Overmeyer Reinhard ,   Department of Anaesthesiology and Critical Care, Stellenbosch University, South Africa., Domingo Abdurragmaan ,   Department of Anaesthesiology and Critical Care, Stellenbosch University, South Africa.
Published: January 2022

Diabetes insipidus is commonly attributed as post-surgical complication of neurosurgical procedures. The case presented here describes the antithesis, where a young man with nephrogenic diabetes insipidus requires emergency neurosurgical intervention. Complex treatment goals and fluid strategies are discussed. Keywords: nephrogenic diabetes insipidus; fluid management; traumatic brain Injury.
Mental retardation and oral health: An insight
Authors:   Reader, Department of Periodontics, College Of Dental Sciences, Davanagere-577004, Karnataka, India., Tatuskar Pramod V , KL Vandana ,   Senior Professor, Department of Periodontics, College Of Dental Sciences, Davanagere-577004, Karnataka, India.
Published: January 2022

Mental Retardation (MR) is a genetic disorder mainfested in significantly below average overall intellectual functioning and deficits in adaptive behaviour. It is a particular state of functioning that begins in childhood and is characterized by decreased intelligence and adaptive skills and also is the most common developmental disorder, often missed by clinicians. The condition is present in 2 to 3 percent of the population, either as an isolated finding or as part of a syndrome or broader disorder. Looking at varies studies it was concluded that the oral health situation of these groups must be improved and a suitable system devised for delivery of preventive measures. Special consideration must be given to improving the oral health of these groups. Oral health should be included in each child’s individual health care plan with oral health promotion programmes aimed specifically at special needs schools and their parents. Children should be instructed to clean their teeth twice a day and oral hygiene should be practised at school and supervised by teachers. There should be a provision for in-service training for teachers, school staff and parents on how to promote good oral health specifically for these children with disabilities.
Desmoplastic fibroma of bone: A morphological and immunohistochemical characterization
Authors:   Universidad Abierta Interamericana-CONICET, Centro de Altos Estudios en Ciencias Humanas y de la Salud, Buenos Aires, Argentina., Cao Gabriel , Ottaviano Graciela ,   Universidad Abierta Interamericana-CONICET, Centro de Altos Estudios en Ciencias Humanas y de la Salud, Buenos Aires, Argentina., Fusaro Analía ,   División Anatomía Patológica, Hospital General de Niños “Dr. Pedro de Elizalde”, Buenos Aires, Argentina., Mendez Julián ,   División Anatomía Patológica, Hospital General de Niños “Dr. Pedro de Elizalde”, Buenos Aires, Argentina., Navacchia Daniel ,   División Anatomía Patológica, Hospital General de Niños “Dr. Pedro de Elizalde”, Buenos Aires, Argentina.
Published: January 2022

Background: Desmoplastic Fibroma (DF) of bone is a locally aggressive and infrequent benign neoplasm. Recently was described a role of vascular endothelial growth factor in the interstitial fibrotic processes. Case presentation: A 13-year-old female presented with pain, swelling and limitation of movements in right forearm. An osteolytic lesion at the distal end of the right radius was shown, with pathologic concentration of Technetium 99 and slight enhancement of soft tissue lesion employing computerized axial tomography. The surgical biopsy showed nodular formations of hyalinized collagen fibers arranged in thick bands with few well-differentiated interstitial fibroblasts / myofibroblasts, focally expressing VEGF-A. Conclusion: The intramedullary neoplastic proliferation is limited by the cortical bone, provoking compression of the intratumorally micro-vessels, favoring both, the extracellular matrix and VEGF-A synthesis. Future research should include therapeutic intervention with anti-CD117 and anti-VEGF-A drugs, with the aim of limiting tumor growth, facilitating the complete surgical excision of the neoplasm. Keywords: desmoplastic fibroma; vascular endothelial growth factor; hyalinization; neoplasm progression.
Diplopia and skin rash in a patient treated with immunotherapy nivolumab regimen
Authors:   Resident of Internal Medicine, Metaxa Cancer Institute, Piraeus, Greece., Papadimitriou Theodora-Maria , Liatsos Alexandros-Nikolaos ,   Resident of Nephrology, Evaggelismos General Hospital, Athens, Greece., Symeonidis David ,   Resident of Medical- Oncology, Metaxa Cancer Institute, Piraeus, Greece., Xynogalos Spyridon ,   Head of Medical- Oncology Department, Metaxa Cancer Institute, Piraeus, Greece.
Published: January 2022

This is a case report of an 80-year-old caucasian male patient with metastatic urothelial bladder carcinoma and bone/liver metastases, who was being presented with diplopia, raynaud’s syndrome and skin rash on both legs, in response to immunotherapy with anti-PDL-1 Nivolumab regimen.
Anal canal epithelioid sarcoma: Case report and literature review
Authors:   Department of Neurological Surgery, National Institute of Neurology and Neurosurgery “Manuel Velasco Suarez” (INNN), 3877 Insurgentes Sur Av, La Fama, Tlalpan, 14269 Mexico City, Mexico., Bárbara V Cárdenas-Almaraz , Gabriela Capdeville-Jímenez ,   Department of Neurological Surgery, National Institute of Neurology and Neurosurgery “Manuel Velasco Suarez” (INNN), 3877 Insurgentes Sur Av, La Fama, Tlalpan, 14269 Mexico City, Mexico., Diego Molina-Botello ,   Department of Neurological Surgery, National Institute of Neurology and Neurosurgery “Manuel Velasco Suarez” (INNN), 3877 Insurgentes Sur Av, La Fama, Tlalpan, 14269 Mexico City, Mexico., Ignacio J Pérez-Martínez ,   Department of Neurological Surgery, National Institute of Neurology and Neurosurgery “Manuel Velasco Suarez” (INNN), 3877 Insurgentes Sur Av, La Fama, Tlalpan, 14269 Mexico City, Mexico.
Published: January 2022

Soft tissue tumors account for less than 0.1% of colon and rectum malignant neoplasms. Epithelioid sarcoma is a subtype of undifferentiated soft tissue neoplasia that makes up 1% of this category; it is characterized by a slow progression, commonly affecting young male adults, with little or no response to chemotherapy and radiotherapy, leaving surgical resection their main therapeutic option to reduce recurrence. We here present the case of a 71-year-old male patient admitted for major rectorrhagia after evacuations and anal pain. During physical examination, a posterior anal sphincter induration was noted, which extended to the puborectal muscle. Anoscopy was performed where a thrombosed hemorrhoidal bundle was detected adjacent to a mass. In the later biopsy with immunohistochemistry, a proximal ulcer type, histological grade three epithelioid sarcoma was diagnosed. Subsequently, traditional abdominal perineal resection with colostomy was performed, resulting in favorable postoperative evolution and discharge after six days of the procedure. Keywords: soft tissue tumors; epithelioid sarcoma.
MIS-A associated myocardial injury: The art of diagnosis and follow-up
Authors:   Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA., Nzemenoh Bellony , Agdamag Arianne C ,   Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, MN 55455, USA., Maharaj Valmiki ,   Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, MN 55455, USA., Charpentier Victoria ,   University of Minnesota Medical School, Minneapolis, MN 55455, USA., Albrecht Kellen ,   Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, MN 55455, USA., Alexy Tamas ,   Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, MN 55455, USA.
Published: January 2022

Multisystem inflammatory syndrome in adults (MIS-A) is a rare but severe condition in adults with a clinical course similar to that described in children (MIS-C) following infection with the SARS-CoV-2 virus. Here we describe a case of a 21-year-old, otherwise healthy female who presented with chest pain and signs of sepsis six weeks after recovering from coronavirus disease 2019 (COVID-19). Early identification of MIS-A led to a favorable clinical course and full recovery. Given the highly variable disease presentation yet potentially deadly outcome, providers must remain vigilant to recognize and treat MIS-A early Keywords: MIS-A; myocardial inflammation; SARS-CoV-2; COVID-19 disease.
“Tineariasis” (or plaque-psoriasis induced by Terbinafine)
Authors:   Dermatology Department, Clinica Dermatologica Internacional, Madrid, Spain., JL Ramirez-Bellver , G Segurado-Miravalles ,   Dermatology Department, Clinica Dermatologica Internacional, Madrid, Spain., L Bagazgoitia ,   Dermatology Department, Clinica Dermatologica Internacional, Madrid, Spain., C Moreno ,   Pathology Department, Hospital Universitario Ramon y Cajal, Madrid, Spain, R Ruiz-Rodriguez ,   Dermatology Department, Clinica Dermatologica Internacional, Madrid, Spain.
Published: January 2022

Terbinafine is an anti fungal drug used worldwide to treat dermatophytosis. Although generally is well tolerated, several cutaneous side effects have been described. One of them is the induction or exacerbation of psoriasis, especially the pustular type. We describe a case of plaque-psoriasis induced by terbinafine in a young patient. Skin biopsy was performed to confirm the diagnosis and the suspected drug was discontinued. Biopsy showed regular epidermal hyperplasia with parakeratoses and neutrophils in the corneal layer. No fungal elements were observed. Improvement was observed after discontinuation of terbinafine. We present a new case of the induction of plaque-psoriasis after the use of oral terbinafine and conclude that this drug should be used with caution in predisposed patients. Keywords: psoriasis; pustular posriasis; plaque-psoriasis; terbinafine
Intrabiliary papillary myxoma: A case report
Authors:   Zunyi Medical University, Zunyi, Guizhou 563003, China., Hexiao Lu , Shenglong Zhang ,   Department of General Surgery, Chengdu Second People’s Hospital, Chengdu, Sichuan 600017, China., Sandeep Bhushan ,   Department of Cardiothoracic surgery, Chengdu second People’s Hospital, Chengdu, Sichuan 610017, China, Sineng Yin ,   Department of General Surgery, Zunyi Medical University, Chengdu Second People’s Hospital, Chengdu, Sichuan 600017,China
Published: January 2022

In 2010, the World Health Organization (WHO) classified intraductal papillary mucinous tumor (ipmn-b) as a solid tumor of the liver producing mucinous bile, which is rare and difficult to diagnose. We reported a 71 year old female patient with ipmn-b due to abdominal pain. Through the description of the causes, diagnosis, treatment and prognosis, we can get a better understanding of the disease. Ipmn-b is considered as a kind of benign precancerous lesion of cholangiocarcinoma with good prognosis. Keywords: papillary mucinous tumor; cholangiocarcinoma; neoplasm.
Presumed topography of basal ganglion: Derived from TRODAT images in a case of hemorrhagic stroke complicated with asymmetrical cogwheel rigidity
Authors:   Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan., Chen Li-Yin , Chiu Yu-Li ,   Department of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan., Chang Yuan-Ling ,   Department of Anaesthesiology, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan., Ding Ruei-Sian ,   Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan., Chang Shin-Tsu ,   Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital, School of Medicine, National Defence Medical Center, Taipei, Taiwan.
Published: January 2022

Introduction: Systemic maps of basal ganglion lesion corresponding to clinical symptoms are lacking at present. Only the framework of functional domains in striatum was presumed. We present a case with asymmetrical cogwheel rigidity which is related to the lesion site of the basal ganglion in his functional brain image. Case presentations: A 50-year-old male who suffered from subarachnoid hemorrhage and intracranial hemorrhage presented with upper limbs cogwheel rigidity. The symptom was more severe in the right side than the left side. Dopamine transport images revealed bilateral decreased dopamine transporter binding capacity in bilateral striatum. In left striatum, decreased uptake in dorsal region is more severe than ventral region. Cogwheel rigidity was mildly improved after use of pramipexole. Conclusions: This case report suggests that asymmetrical cogwheel rigidity is linked to the lesion site of the basal ganglion. Topography exists in the striatum and is related to dysfunctional site of parkinsonism. Keywords: cogwheel rigidity; asymmetrical cogwheel rigidity; parkinsonism; basal ganglion; topography
The role of beta-agonist therapy for chronic obstructive airway disease in patients with coexistent atrial fibrillation: Literature review
Authors:   Montefiore Medical Center, Albert Einstein College of Medicine, Department of Medicine, Bronx, NY, USA., Miguel Rodríguez , Siddharth Chinta ,   BronxCare Hospital Center, Icahn School of Medicine at Mount Sinai, Department of Internal Medicine, Bronx, NY, USA., Timothy Vittorio ,   BronxCare Hospital Center, Icahn School of Medicine at Mount Sinai, Division of Cardiology, Bronx, NY, USA.
Published: January 2022

Background: New advances have been made in medicine, but the incidence and prevalence of Chronic Obstructive Pulmonary Disease (COPD) are evident, and it is established as the fourth cause of death in the United States representing a high cost for the healthcare system. This condition has been related to atrial fibrillation due to the changes in the lungs and vasculature. Based on this history, we seek to evaluate the outcome of AF in the patients with COPD and its relationship with medical therapy utilized to treat this pulmonary condition with the objective of establishing the relationship between the use of beta-agonist therapy for obstructive airway disease in patients with AF. Discussion: Cell receptors participate in multiple reactions and the sympathetic response is received via the alpha- and beta-receptors are related to the hemodynamic of the vasculature of the lungs and cardiovascular system. The beta-blockade agents are one of the most common medication classes used for rate control in cardiac arrhythmias, but the side effect could be COPD exacerbation; on the other hand, beta-adrenergic or beta-agonist as a therapy for this pulmonary condition could increase the heart rate leading to AF decompensation. There is a clear dilemma in our patients who have airway disease and AF since the treatment for one might worsen the other. The clear benefit in morbidity and mortality of beta-blocker therapy, especially beta1-selective, outweighs the potential for any pulmonary side-effects related to ex-acerbation of COPD or airway disease. Conclusion: There is clear data showing the evidence of the potential paradoxical side-effect between COPD and AF therapies, given the exacerbation of one due to treatment of the other, benefits versus risks should be discussed and the medical decision should be made based on them. The deteriorated cardiac condition can rapidly predispose to critical complications leading to death, which is why the use of beta-blockade agents will be chosen over possible complications with pulmonary disease. In other words, the benefit should outweigh the risk based on the best outcome for the patient. Keywords: atrial fibrillation; pulmonary disease; obstructive pulmonary disease; chronic obstructive pulmonary disease (COPD); B-Agonist; B-Block (selective; non-selective); digitalis; other antiarrhythmic.
Studi Komparatif Pelaksanaan Peradilan Pidana Islam di Negara Republik Arab Mesir dan Negara Republik Indonesia (Provinsi Nanggroe Aceh Darussalam)
Authors: Rahmadiana Annisa
Published: January 2022

Abstract:

This article discusses the implementation of Islamic criminal justice in Indonesia, especially in the Province of Nanggroe Aceh Darussalam and the Arab Republic of Egypt. Between Egypt and Indonesia have the same reference in the implementation of Islamic law in the judiciary, namely referring to the Qur'an and Hadith. The Aceh Syar'iyah Court has a position as part of a special judicial institution under the auspices of the general court and the religious court according to the type of case being handled. Meanwhile, the Court in Egypt has a wider scope with each function and authority according to its level. The research method used in the preparation of this article is a comparative study by comparing the similarities and differences inherent in Indonesia and Egypt in terms of the implementation of Islamic law which is studied through reading materials, including books, laws and regulations, and various other related sources.

Keywords : Court, Judiciary, Islamic Law, Aceh, Egypt
Keterkaitan Arah Kebijakan Lingkungan Pasca Undang-Undang Tentang Cipta Kerja dengan Manajemen dan Kebijakan Lingkungan Sektor Militer
Authors: Susdarwono Endro Tri , Susdarwanto Eko
Published: January 2022

Praktik UU Cipta Kerja terkait lingkungan berpengaruh terhadap manajemen lingkungan militer berupa penyiapan dan penataan wilayah negara sebagai medan pertahanan dan penyiapan logistik wilayah. Penelitian ini bertujuan meneliti mengenai keterkaitan arah pembangunan pasca UU Cipta Kerja dengan manajemen dan kebijakan lingkungan sektor lingkungan. Dalam penelitian ini pendekatan yang digunakan adalah kombinasi antara kualitatif dan kuantitatif. Metode pendekatan kualitatif yang digunakan adalah yuridis normatif analitis substansi hukum sedangkan pendekatan kuantitatif menggunakan pengujian hipotesis atas tanda guna menganalisis dampak yang timbul karena terjadinya suatu hal. Kesimpulan dari penelitian ini adalah UU Cipta Kerja dalam implementasinya berpotensi melemahkan instrumen yang terkait manajemen dan kebijakan lingkungan sektor militer yaitu perlindungan lingkungan hidup, hak-hak masyarakat dan juga berpotensi memberikan dampak negatif terhadap kualitas lingkungan hidup. Hal ini juga diperkuat dengan hasil pengujian hipotesis atas tanda bahwa terjadi perubahan dalam membangun respons manajemen lingkungan standar yang harus digunakan untuk semua komponen, sipil atau militer.
Study of the biology and ecology of the Muscidae Family (Insecta: Diptera): Collections
Authors: Carlos Henrique Marchiori
Published: January 2022

Adults can be predators, hematophagous and detritivores or feed on numerous types of exudates from plants or animals. They can be attracted to various substances including sugars, sweets, tears, and blood. Larvae appear in a variety of habitats, including decaying vegetation or animals, dry or moist soil, insect, or bird nests, fresh or stagnant water, and droppings. The objective of the mini review consists of bibliographical research on the muscoid dipterans of the Family Muscidae. The research was carried out in studies related to quantitative aspects of the Family and Species (taxonomic groups) and in conceptual. A literature search was carried out containing articles published from 1971 to 2021. The mini review was prepared in Goiânia, Goiás, from August to September 2021, through the Online Scientific Library (Scielo), internet, ResearchGate, Academia.edu, Frontiers, Publons, Qeios, Portal of Scientific Journals in Health Sciences, https://goo.gl/gLTTTs and https://www.growkudos.com/register. Although some species are very common worldwide, such as the housefly and the stablefly due to their synanthropy, most species do not have this behavior, so they are restricted to some territorial areas, sometimes-small dimension.
Progresses in the production of ethanol from lignocellulosic biomass using Saccharomyces cerevisiae by fermentation engineering
Authors: Richmond Godwin Afful  , Tracy Naa Adoley Addotey  , Samaila Boye Ajeje
Published: January 2022

Ethanol fermentation is a biological procedure which converts sugars such as glucose, fructose, and sucrose into cellular energy, producing ethanol and carbon dioxide as by-products. Since yeasts perform this conversion in the absence of oxygen, alcoholic fermentation is generally considered to be an anaerobic process. Ethanol fermentation has many uses, including the production of alcoholic beverages, the production of ethanol fuel, and bread making. The increasing demand for biofuels around the globe has also prompted the necessity to seek other means to meet the demands. In this review, the general ideologies, methodologies, general chemistry and biochemistry and conditions of the production of ethanol by fermentation engineering using Saccharomyces cerevisiae are highlighted. The quest to reduce pressure on staple foods has necessitated the attention now given to the use of lignocellulose biomass, despite the complexity of the process. It concludes by suggesting ways to improve yield and commercialization of the use of lignocellulosic biomass for ethanol fermentation.
A Snapshot of Risk Stratification of Diabetic Patients Fasting during the Month of Ramadan
Authors: Hassan Asim , Abullah Aldahasai Wedad , Abdulatif Alsalmi Shayma
Published: January 2022

Objectives: To get a clinical snapshot of the diabetic patients who planned to fast during the month of Ramadan and to determine the ability of the RRR application to effectively risk-stratify patients. Study Design: Observational study. Place and Duration of Study: Department of Diabetes & Endocrinology, Armed Forces Hospital Al-Hada, Taif, Kingdom of Saudi Arabia from 1st April 2018 to 31st May 2018. Methodology: Ninety six patients over 15 years of age with diabetes mellitus were risk stratified using standardized risk criteria were enrolled. Detailed analysis of the information was performed to paint a clinical landscape of the patients who intended to fast. Results: Seventy four percent of the patients were type 2 diabetics, 11% GDM, 31% were between 60-70 years and 17 % had diabetes for more than 20 years. 17% of participants had serious complications during the last three months before Ramadan including hypoglycemia, Diabetic Ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS). 59% had chronic diabetic complications. 28 % of patients were on both insulin and oral hypoglycemic agents (OHA) together and 16 % on high risk medications. 25% of patients had an HbA1C of more than 10%. Pertaining to the previous Ramadan experience 19% disclosed having serious complications in the past. 6 % were categorized as low risk individuals, 76% as moderate, 6% high and 12 % as very high risk. Conclusions: Astonishingly all the patients advised to refrain from fasting insisted on fasting. Considering the latest IDF numbers the above calculated percentages would translate into very huge numbers who are in serious jeopardy. In order to prevent serious consequences it is highly recommends that evidence based and validated risk stratification strategies are implemented in routine clinical practices. Keywords: Diabetes mellitus, Fast, Hypoglycemia, High risk patients
Frequency of Dyslipidemia in patients with Psoriasis and Association with Disease Severity
Authors: Kiran Ayesha , Babar Zahra , Naheed Aqsa , Awan Sobia , Fatima Bilqees , Mirza Urooj , Rehman Farid-ur-
Published: January 2022

Background: Psoriasis is a recurrent disfiguring skin disease, associated with abnormal lipid metabolism and with high occurrence of cardiovascular complications. This linked to the extent of disease, as it is often seen in those patients who have larger body areas involved with psoriasis. Objective: To estimate frequency of dyslipidemia in psoriatic patients and to determine the frequency of dyslipidemia in psoriatic patients based on the severity of disease. Study Design: Cross-sectional study Place and Duration of Study: Department of Dermatology, Fauji Foundation Hospital Rawalpindi from 1stMarch 2017 to 30th September 2017. Methodology: One hundred and fifty cases were enrolled. All cases were enrolled and 3ml of blood was collected following 12 hrs of fasting for determination of lipid profile. Blood sample was sent to the Hospital laboratory and reports were verified by senior pathologists. Severity of psoriasis was determined according to PASI score. Results: Age of participants was between 18-60 years with mean 38.88±12.26 years and 29 (19.33%) male and 121 (80.67%) female cases. According to severity of disease, 50 (33.3%) cases had mild, 70 (46.7%) had moderate and 30(20%) cases had severe Psoriasis. The mean cholesterol, triglycerides (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL) was 12.91 ± 2.17, 8.93 ± 2.90, 5.0 ± 2.28 and 1.98 ± 0.31 respectively. There were 100(66.7%) cases who had dyslipidemia and 50(33.3%) had normal lipid profile. Conclusion: Frequency of dyslipidemia is very high and is associated with severity of psoriasis. Keywords: Psoriasis, Dyslipidemia, Lipid profile and Cardiovascular disease.
Identification of Nephron Progenitor Cells from WT1 through Amniotic Fluid as a Stem Cell Initiator
Authors: Jabeen Hina , Wahid Mohsin , Ahmed Shaikh Naveed , Ali Sohail Muhammad , Ahmed Junaid , Rasheed Shaikh Abdul
Published: January 2022

Background: The incidence of kidney disease is prevailing worldwide and there is an urgent requirement for regenerative techniques such as stem cells. Objective: To identify nephron progenitor cells from transcriptional factor WT1. Study Design: Experimental analytical study Place and Duration of Study: Dow Research Institute of Biotechnology & Biomedical Sciences, Dow International Medical College, Karachi from 1st January 2019 to 31stDecember 2019 Methodology: 40 ml of amniotic fluid was extracted from 10 full term women at the time of elective caesarean. Using cell culturing, inverted phase contrast microscopy and flow cytometry techniques in addition to immune-florescence the nephron progenitor cells were identified. Results: The mean age of women was 30.3±0.4 years. Out of total 10 million WT1 expressed in three samples 1.4 million nephron progenitor cells were identified. Conclusion: Identification of nephron progenitor cells is feasible procedure for designing stem cell lines through amniotic fluid. Key words: Progenitor cell, Amniotic fluid, Stem cell initiator
Plaque Removal Efficacy of Dental floss Compare to Water Jet Following Single Use
Authors: Batool Syed Midhat , Rasheed Madiha , Syed Kawish , Farooq Afaq , Ayub Zain , Raheem Abid
Published: January 2022

Background: Dental plaque (biofilm) is a well-known contributor to the onset and progression of many dental illnesses. Plaque is a natural biofilm that develops on oral surfaces and contains a wide variety of organisms. As a result, it is critical to control plaque formation, particularly in the young population, by implementing effective preventive strategies. Objective: To assess and compare plaque removal efficacy of water flosser and string floss in patients. Study design: Randomized controlled trial Place and Duration of study: Department of Periodontology, Sardar Begum Dental College, Gandhara University from 1st March 2019 to 31st May 2019. Methodology: Seventy patients were enrolled. Patients were randomly allocated to one of two groups, group A (using dental floss) as the control group and group B (using waterpik) as the intervention group, using the lottery technique. Patients were randomly allocated to one of two groups, group A (control group), using dental floss and group B (intervention group), using waterpik utilizing the lottery technique. All participants were taught correct brushing technique utilizing the Modified Bass technique and manufacturer's instructions for using waterpik as well as normal flossing instructions for using Dental floss. Results: The mean age presentation was 34.23±6.78 years. The females were 42 (60%) males were 28 (40%). The mean percentage showed that those using water flosser with tooth brushing had low plaque score than using string floss with tooth brushing. The independent t test showed that water flosser is significantly more effective (p=0.001) in plaque reduction than conventional string floss. Conclusion: A water flosser coupled with hand brushing is more effective in eliminating plaque than string floss. Plaque removal was 20-30% higher in the group that used a water flosser. Key words: Efficacy, Dental floss, Water jet
Smile Aesthetics Acuity of Lay-persons verses Dental Professionals
Authors: Ahmed Sadia Nisar , Falak Nazish , Batool Iffat , Gul Kemia , Amin Arsalan , Yousafzai Brekhna
Published: January 2022

Objective: To compare and evaluate the perception of smile aesthetics by lay-persons and dental specialists. Study Design: Cross-sectional study Place and Duration of Study: Department of Orthodontics, Bacha Khan College of Dentistry/Medical Teaching Institute, Mardan from 1st April 2020 to 31st July 2021. Methodology: Eighty participants were assessed for their smiles through photographical imaging to assess each photographic image of smile (frontal view) and categorized them as very good, good, average or bad. Results: The mean age was 20.59±3.1 years with 59 females and 21 males. The laypeople assessed smile under categories of very good (60%) or good with a least number of people categorizing it average or bad. Contrary to this the dentist perception about smile aesthetic was completely reveres. Conclusion: There is an obvious variance between perception of laypeople and dentists with dentist being more analytical and judgmental. Key words: Incisors, Smile, Aesthetic, Smile arc
To Compare the Graft Uptake in Permeatal versus Postaural Approaches in Myringoplasty
Authors: Shinwari Wajih-ud-Din , Ali Amjad , Mustafa Sadaf Raffat , Mushahid Uzair , Jamil Muhammad , Khan Azmatullah
Published: January 2022

Objective: To compare the graft uptake in permeatal versus postaural approaches in myringoplasty. Study design: Cross sectional comparative Place and Duration of Study: Department of ENT, Head and Neck Surgery, Pakistan Institute of Medical Sciences/Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad Pakistan from 1st March 2018 to 31st December 2018. Methodology: Seventy two patients were classified into two equal groups. Thirty six patients underwent myringoplasty by permeatal approach and thirty six patients underwent postaural approach. Those patients were included who had mucosal type moderate central perforation with inactive disease with age 15-42 years and those patients were excluded who had small, subtotal, total, squamosal type atticoantral tympanic membrane perforation, with comorbidities and pregnancy. Results: Thirty seven were (51.4 %) males and 35 (48.6%) were females. In both the groups the success of graft uptake was 52 (72.2%) patients and graft rejection in 20 (27.8%) patients. In each group there were 36 patients. The graft uptake in permeatal approach was 30 patients (83.3%), while the graft uptake in postaural approach was 22 (61.1%) patients. The overall graft uptake in permeatal approach is more as compared to postaural approach (p=0.035). Conclusion: The permeatal approach is better than the postaural approach in terms of graft uptake in medium sized central perforations in myringoplasty. Key words: Myringoplasty, Tympanoplasty, Permeatal, Postauricular
Women, Journalism, and Discrimination in Indonesia Digital Media
Authors: Asnaura  , Zahrani Nisrina , Alifia Suryadi Sarah
Published: January 2022

Permasalahan kesetaraan gender dalam kehidupan jurnalistik masih perlu diperhatikan, diskriminasi gender bahkan pelecehan yang dialami oleh jurnalis perempuan dilakukan ketika sedang melaksanakan peliputan. Tujuan dari penelitian ini adalah untuk mengetahui diskriminasi yang dihadapi oleh jurnalis perempuan dan cara untuk menghadapi diskriminasi dalam pekerjaan mereka. Jenis metode yang di gunakan dalam penelitian ini adalah metode kualitatif deskriptif. Objek atau sumber pada kajian penelitian ini adalah data sekunder berupa berita-berita terkait diskriminasi yang diterima oleh jurnalis perempuan serta penelitian terdahulu. Penelitian ini merupakan studi pustaka, observasi, dan analisis wacana secara kritis. Peneliti menggunakan instrumen checklist untuk membantu dalam menganalisis data. Berdasarkan hasil penelitian diskriminasi terhadap perempuan masih banyak terjadi, khususnya di kalangan jurnalis. Diskriminasi gender yang dialami oleh jurnalis perempuan berupa pembedaan pemberian upah, penempatan posisi, fasilitas yang kurang memadai untuk kebutuhan jurnalis perempuan serta pelecehan yang dialami ketika sedang melakukan peliputan. Dalam hal ini jurnalis perempuan melakukan upaya untuk memperjuangkan kesetaraan gender dan diskriminasi yang dialami dengan mengangkat isu-isu terkait perjuangan terhadap kesetaraan gender untuk perempuan terutama dalam bidang jurnalistik.
Pola Komunikasi Interpersonal dalam Membentuk Kemandirian Anak Berkebutuhan Khusus
Authors: Rahma Fitri Dayana  , Bunyamin
Published: January 2022

Anak Berkebutuhan Khusus yang di besarkan di lembaga sosial memiliki hak yang sama seperti anak yang tumbuh kembangnya dalam lingkungan keluarga. Salah satu bentuk komunikasi yang terjadi antara pengasuh kepada anak berkebutuhan khsus untuk memberikan motivasi serta nasihat dalam  hal membentuk kemandirian adalah komunikasi interpersonal. tujuan penelitian ini adalah untuk membahas bagaiamana tahapan komunikasi interpersonal serta pola komunikasi interpersonal pengasuh Lembaga Kesejahteraan Sosial Anak (LKSA) Villa Do’a Yatim Sejahtera terhadap anak berkebutuhan khusus dalam membentuk kemandirian. Untuk menjawab rumusan masalah diatas penelitian ini menggunakan penelitian berjenis kualitatif yang bersifat deskriptif serta menggunaka teori penetrasi sosial.  Adapun hasil penelitian ini adalalah terdapat empat tahapan komunikasi interpersonal yakni tahap orientasi, tahap pertukaran eksplorasi, tahap pertukaran afektif, dan tahap pertukaran stabil yang digunakan oleh pengasuh Lembaga Kesejahteraan Sosial Anak (LKSA) Villa Do’a Yatim Sejahtera kepada anak berkebutuhan khusus serta pola komunikasi roda dan pola komunikasi bintang dapat membentuk kemandirian anak
Media Komunikasi Guru Terhadap Penyandang Tunarungu Selama Pandemi
Authors: Trika Fitria  , Sutamaji  , Muhammad Amrillah
Published: January 2022

Komunikasi merupakan suatu proses sosial yang mendasar dalam kehidupan manusia. Dalam berkomunikasi sering kali menemukan hambatan dalam proses penyampaian pesan. Khususnya berkomunikasi dengan seorang penyandang tunarungu yang mengalami gangguan pada pendengaran. Mengajar anak tunarungu diperlukan strategi tersendiri dalam penggunaan media pembelajaran. Apalagi selama pandemi Covid-19 dibutuhkan media pembelajaran yang efektif dari seorang guru kepada siswa tunarungu dalam mengajar dan memberikan intruksi pengetahuan sesuai dengan kurikulum yang ada disekolah. Salah satunya yaitu penggunaan media komunikasi nonverbal baik dilakukan dalam jaringan ataupun luar jaringan selama pandemi. Metode penelitian ini menggunakan pola penelitian deskriptif dan studi kasus dengan pendekatan kualitatif. Hasil penelitian menunjukan bawah media komunikasi guru dalam proses belajar mengajar terhadap siswa penyandang tunarungu selama pandemi di SDLB Shanti Kosala Mas Trip adalah berbentuk buku LKS yang telah dimodifikasi oleh guru sesuai tingkat ketunaan siswa dan Handphone sebagai alat dan sarana guru dengan siswa dan wali murid dalam proses pembelajaran selama pandemi agar tetap terjalin secara efektif. Sedangkan media yang digunakan yaitu internet dengan memanfaatkan aplikasi WhatsApp, Zoom Meeting dan Google Classroom.
Knowing Communication Strategy for Better Communication
Authors: Rona Merita  , Sony Eko Adisaputro
Published: January 2022

Nowadays, the importance of communication is undeniable. In oral communication, the learners employ speaking skills which requires the mastery of communication strategies in order to solve the communication problems which they found during oral communication and to get across the communicative goals to the interlocutors. Unfortunately, speaking is still considered one of the most difficult skills to be acquired by English language learners. English learners need more practices and also strategies in communication. In addition, communication ability also influenced by some factors such as target language proficiency, learning and communicating contexts, task types, gender differences and learners’ personality. Driven by this condition, this paper is aimed to discuss theoretical framework about communication strategies and its development since firstly proposed by Tarone (1977). This paper is beneficial for English language practitioner and English language learners, ELT researcher as well.
Model Pembelajaran Berbasis Aktivitas pada Siswa Kelas VII di MTs Al-Hidayah Sungai Tabukan
Authors: Ramdhani
Published: January 2022

Tujuan penelitian ini untuk mengetahui dan mendeskripsikan tingkat pendekatan berbasis aktivitas dalam menumbuhkan motivasi belajar aqidah akhlak pokok bahasan Taubat MTs Al-Hidayah Sungai Tabukan  pada siswi kelas VII B  pada semester I tahun pelajaran 2020/2021. Penelitian ini merupakan penelitian tindakan kelas yang ingin mengungkap seberapa tinggi tingkat efektifitas pendekatan berbasis aktivitas dalam menumbuhkan motivasi belajar aqidah akhlak pokak bahasan Taubat  pada siswi kelas VII. Lokasi penelitian tindakan ini adalah Madrasah Tsanawiyah Al-Hidayah Sungai Tabukan, kelas VII B semester I terdiri dari 14  siswi. Hasil penelitian menemukan bahwa pembelajaran materi taubat  dengan menggunakan metode Saintifik/inquiry pada siswi kelas VII B dirasa dapat meningkatkan proses pembelajaran materi taubat. Dimana dapat dilihat dari peningkatan rata-rata perolehan skor dari siklus 1 sebesar (85%) dan meningkat pada siklus 2 sebesar (95%).
Penggunaan Website dan Internet dalam Pembelajaran
Authors: Said Zulfikar
Published: January 2022

Penelitian ini bertujuan untuk membangun pemahaman serta menyelesaikan latihan pembelajaran terhadap pendidik dan untuk mendapatkan data tentang pemanfaatan website dan internet sebagai pengembangan pembelajaran di sekolah. Sasaran mendasar dari penelitian tersebut adalah untuk memutuskan pemanfaatan model pembelajaran yang menggunakan model berbasis website dan internet. Metode penelitian menggunakan pendekatan kualitatif studi literatur atau penelitian perpustakaan, membaca dan memeriksa beberapa artikel nasional  untuk menjawab tujuan penelitian tersebut. Hasil penelitian menemukan pengertian, pemanfaatan, kekurangan website dan internet dalam pembelajaran. Hal ini sangat mempengaruhi pengajar dalam menyampaikan materi ajar terhadap pendidik yang telah diputuskan, serta dapat diterima sesuai dengan sarana dalam model pembelajaran. Sehingga dapat memberikan waktu kepada pendidik untuk berpikir dalam sistem pembelajaran. Demikian pula dengan latihan pembelajaran, pendidik memiliki pilihan untuk mengikuti sistem pembelajaran dengan baik dan penuh semangat  menggunakan website dan internet sebagai bahan untuk mengungkap data. Hal ini terlihat dari korelasi jika mereka tidak menggunakan website dan internet dalam menggali data, maka mereka pada umumnya akan mengalami keterlambatan dalam memahami pembelajaran.
Peningkatan Kedisplinan Belajar Pendidikan Agama Islam Melalui Pembiasaan Tadarrus Siswa
Authors: M. Rijal
Published: January 2022

Penelitian ini bertujuan untuk mengetahui bagaimana pembiasaan tadarrus dapat meningkatkan Kedisplinan siswa pada mata pelajaran pendidikan agama Islam Kelas 8.A di SMP Negeri 9 Balikpapan. Penelitian ini dirancang dengan Penelitian Tindakan Kelas (PTK) atau yang disebut classroom action research, prosedur pelaksanaan tindakan kelas dalam penelitian ini diatur dalam skenario model penelitian tindakan kelas dengan rancangan distrukturkan dalam dua siklus, dimana Siklus I merupakan prerekuiset dari siklus berikutnya. Setiap siklus terdiri dari 4 tahapan (langkah), yaitu Perencanaan, Pelaksanaan, Pengamatan dan Refleksi, Hasil penelitian menemukan adanya peningkatan persentase kedisplinan belajar siswa pada pelajaran PAI pada saat pembelajaran, sebelum tindakan sebesar 30% (3 siswa) menjadi 50% (10 siswa) pada siklus I, dan pada siklus II meningkat menjadi 80% (8 siswa). Pada awal siklus terdapat beberapa kelemahan dalam proses pembelajaran, tetapi setelah diadakan refleksi dan perbaikan maka proses pembelajaran pada siklus II dapat mencapai keberhasilan sesuai target yang diharapkan. Jadi semua indikator kinerja telah tercapai, maka hipotesis tindakan yang berbunyi “Bahwa melalui pembiasaan tadarrus dapat meningkatkan kedisplinan belajar siswa pada mata pelajaran PAI Kelas VIII.A  SMP Negeri 9 Balikpapan.
Studi Literatur: Pengembangan Media Pembelajaran dengan Video Animasi Powtoon
Authors: Ega Safitri  , Titin
Published: January 2022

Tujuan penelitian ini adalah untuk mengetahui (1) kelayakan media pembelajaran dengan video animasi powtoon; (2) respons terhadap media pembelajaran dengan video animasi powtoon; (3) hasil belajar setelah menerapkan media pembelajaran dengan video animasi powtoon. Teknik pengumpulan data dengan cara mengumpulkan beberapa penelitian terdahulu untuk menjawab kelayakan media, respons, dan hasil belajar setelah menerapkan media pembelajaran dengan video animasi powtoon. Penelitian terdahulu yang sudah terkumpul selanjutnya dikompilasi, dianalisis, dan disimpulkan sehingga mendapatkan kesimpulan mengenai pengembangan media pembelajaran dengan video animasi powtoon. Hasil penelitian (1) media pembelajaran dengan video animasi powtoon dikatakan layak karena memenuhi aspek-aspek kevalidan media terhadap video animasi powtoon dengan persentase rata-rata penialain validasi ≥ 61% - 100% dengan kualitatif baik hingga sangat baik, (2) respons terhadap media pembelajaran dengan video animasi powtoon dikatakan baik karena responden menunjukkan ketertarikan terhadap media dengan persentase rata-rata peniaian hasil respons ≥ 61% - 100% dengan baik hingga sangat baik, (3) media pembelajaran dengan video animasi powtoon yang dapat meningkatkan hasil belajar adalah media pembelajaran dengan video animasi powtoon yang telah memenuhi aspek kelayakan media serta hasil uji penerapan media menunjukkan peningkatan hasil belajar setelah menerapkan video animasi powtoon.