bluuebunny/crossref_metadata_2025 huggingface dataset:
Mitochondrial Inherited Disorders and their Correlation with Neurodegenerative Diseases
Authors: Gushi Sofjana , Balis Vasileios
Published: November 2023

Mitochondria are essential organelles for the survival of a cell because they produce energy. The cells that need more mitochondria are neurons because they perform a variety of tasks that are necessary to support brain homeostasis. The build-up of abnormal proteins in neurons, as well as their interactions with mitochondrial proteins, or MAM proteins, cause serious health issues. As a result, mitochondrial functions, such as mitophagy, are impaired, resulting in the disorders described in this review. They are also due to mtDNA mutations, which alter the heritability of diseases. The topic of disease prevention, as well as the diagnosis, requires further explanation and exploration. Finally, there are treatments that are quite promising, but more detailed research is needed.
Applications of Nanomedicine in Brain Tumor Therapy: Nanocarrierbased Drug Delivery Platforms, Challenges, and Perspectives
Authors: Verma Ravinder , Rao Lakshita , Kumar Harish , Bansal Nitin , Deep Aakash , Parashar Jatin , Yadav Manish , Mittal Vineet , Kaushik Deepak
Published: November 2023

Background:

The most difficult kind of cancer to treat is brain cancer, which causes around
3% of all cancer-related deaths. The targeted delivery is improved with the use of technologies based
on nanotechnology that are both safe and efficient. Because of this, there is now a lot of research being
done on brain cancer treatments based on nanoformulations.

Objective:

In this review, the author's primary aim is to elucidate the various nanomedicine for brain
cancer therapy. The authors focus primarily on the advancement of nanotechnology in treating brain
cancer (BC). This review article gives readers an up-to-date look at publications on sophisticated
nanosystems in treating BC, including quantum dots (QDs), nanoparticles (NPs), polymeric micelles
(PMs), dendrimers, and solid lipid nanoparticles (SLNs), among others. This article offers insight into
the use of various nanotechnology-based systems for therapy as well as their potential in the future.
This article also emphasizes the drawbacks of nanotechnology-based methods. Future perspectives
for treating brain cancer using proteomics and biomimetic nanosystems are briefly discussed.

Conclusion:

In this review, we review several aspects of brain cancer therapy, including various nanomedicines,
their challenges and future perspectives. Overall, this article gives a thorough overview
of both the present state of brain cancer treatment options and the disease itself.
An Efficient Suppression of EGFR and B-Raf mRNA Overexpression in the Lung of Benzo[a]pyrene-induced mice by Cationic Lipo-ATRA Nanoformulation
Authors: Mariammal Berlin Grace Viswanathan , Wilson Devarajan David , Siddikuzzaman  , Singaram Viswanathan , Ravichandran Ragavi , Chandrasekharan Guruvayoorappan , Chinnadurai Kathirvelan
Published: November 2023

Background:

The molecular drug all-trans retinoic acid (ATRA) acts on cancer cells via
different molecular pathways, but its poor bioavailability in cancer cells limits its potency. This study
was, therefore, carried out to analyse the oncogene expressions in the lung tissue of benzo[a]pyrene
(B[a]P)-induced mice and compare between free ATRA and cationic liposome nanoformulation (lipo-
ATRA) treatments.

Objective:

This study was designed to analyse the changes in the expression levels of epidermal
growth factor receptor (EGFR) and B-Raf in the lung tissues of B[a]P-induced mice during the cancer
development stage itself and to find the suppressive effect of free ATRA and lipo-ATRA.

Methods:

Lung cancer was induced in mice by oral ingestion of 50mg/kg body weight B[a]P weekly
twice for four consecutive weeks. Then, the mice were treated with free and lipo-ATRA (0.60mg/kg)
for 30 days via i.v injection. The EGFR and B-Raf gene expressions were analyzed in lung cells by
reverse transcriptase polymerase chain reaction (RT-PCR) and quantitative polymerase chain reaction
(qPCR).

Results:

The RT-PCR gene band density and the relative quantity (RQ) values from qPCR revealed
both EGFR and B-Raf genes to be significantly overexpressed in B[a]P control mice while having very
low or no expression in normal mice. This indicates that they function as oncogenes in B[a]P-induced
lung carcinogenesis. The lipo-ATRA treatment has shown a highly significant increase in RQ values
for both EGFR and BRaf when compared to the free ATRA treatment.

Conclusion:

The study results have revealed the cationic lipo-ATRA treatment to have enhanced the
bioavailability of ATRA in lung tissue due to its significant suppression action on EGFR-mediated
oncogenes’ expressions. Furthermore, the EGFR and BRaf could be the molecular targets of ATRA
action in lung carcinogenesis.
Phthalate-induced Toxicity and its Mitigation by Natural Plant Products
Authors: Gaur Kajal , Siddique Yasir Hasan
Published: November 2023

Phthalates are common synthetic chemicals in various industrial and consumer products,
including plastics, personal care products, and medical equipment. They are dangerous
even at extremely low concentrations during the crucial stages of life, such as pregnancy, infancy,
early childhood, and adolescence. In recent years, there has been increased interest in looking
into natural plant components as potential phthalate toxicity mitigators. Phthalates have been
related to a number of health problems, including endocrine disruption, reproductive and developmental
disorders, and carcinogenicity. As a result, effective ways to decrease phthalate exposure
and attenuate its negative effects are required. Natural plant products have shown the potential
to reduce phthalate toxicity via various methods. These methods include antioxidant and anti-
inflammatory properties, detoxifying enzyme regulation, and competition for phthalate binding
sites. Certain plant-derived chemicals, such as polyphenols, flavonoids, terpenes, and alkaloids,
have been shown to interact with phthalates and potentially limit their absorption, distribution,
and metabolism inside the body. This review highlights the effects of several naturally occurring
plant products, such as apigenin, taxifolin, vitamin C, and many more, on the toxicity of
phthalates. Natural products use nowadays is increasing due to their non-toxic nature, so in the
future, more focus should be in favor of increasing the use of these natural products that we obtained
from plants.
Augmented Reality Control based Energy Management System for Residence
Authors: Kandasamy Prabaakaran , Veeramani Thilagar Kannappan , Munusamy Venkatesh , Sanjth Sudharsan , Amurthavalli Sethuraman , Balaji Barath Chander
Published: November 2023

Introduction:

The roots of virtual reality (VR) go back to the work of Ivan Sutherland
in the 1960s. At the time, virtual reality showed promise in universities and labs, peaking in the
early 1990s at a stable level. The latest form of IoT is merging with the Internet of Everything
(IOE). Using this technology, users can access any device, device, and machine in the environment
through any middleware application or system. In recent years, smart speakers have become
a common commercial method for controlling household appliances, solving some of the
problems of remote control. For example, speech recognition is difficult in noisy environments
and is minimized using noise cancellation. It also takes a long time to determine the current state
of the device as the user need to request or issue a command to the smart speaker and need to
wait for a response. The evaluation of prototype system found, using a device with gestures and
interacting with a virtual 3D device instead of a real device was acceptable in terms of usability.
In this article, the Unity and Vuforia are used to create an AR-based IoT virtual switch that can
control any device connected to a LAN controller via HTTP requests.

Methods:

The system is made experimental with the Augmented Reality (AR), the virtual communication
system is designed instead of physical mode. It provide the real time based image for
active control of Energy management. It consist of virtual switches, it supports the AR based
power control system.

Results:

The proposed system are made evaluated and tested under various load conditions. The
virtual image consist of virtual switches to make real time control of power equipment. The proposed
system achieve the latency of about 0.06 sec.

Conclusion:

The advancement in day today activities required with AR based energy management
system with proper control measures. The designed system is supportive for such mechanism.
The further system is proposed to make more energy saving concept for enhancement in
proposed work.
Anti-epidemic Measures of a Community
Authors: Lau Yui-yip , Tang Yuk Ming , Wai Keung Alan Leung
Published: November 2023

In this chapter, the authors mainly highlight the key anti-epidemic measures
adopted by a community. A total of 14 illustrative examples are discussed to
demonstrate the different measures adopted in response to the COVID-19 pandemic.
Details of the measures are provided, including photos, such as in a gym, hospitals,
swimming pools, catering premises, a cinema, theme parks (i.e. Ocean Park and
Disneyland), the Hong Kong Airport, schools, public markets, an elderly home, a
church, museums, the Hong Kong Coliseum and public transportation. The antiepidemic measures were effective in controlling the spread of COVID-19 during the
different waves in the past 3 years. The anti-epidemic measures may provide valuable
insights into the practices and preparation of other countries for the post-COVID-19-
pandemic future.
Homes for the Aged in the COVID-19 Pandemic
Authors: Lau Yui-yip , Tang Yuk Ming , Keung Alan Leung Wai
Published: November 2023

In the context of the COVID-19 pandemic, homes for the aged have
seriously suffered from the fifth wave of COVID-19. Although the problem of an
ageing population emerges as a global issue, the relevant studies related to homes for
the aged are under-researched. In this chapter, we explored the weaknesses of homes
for the aged and weak government policies that have posed threats to homes for the
aged to deal with numerous confirmed cases of COVID-19. In response, we propose
possible ways for homes for the aged to deal with the challenges arising from the
COVID-19 pandemic. It may give useful guidelines for the policymakers, researchers,
homes for the aged, and the local community to design and implement anti-epidemic
measures in the forthcoming years.
The Adoption of Mobile App for the Elderly in the 21st Century
Authors: Lau Yui-yip , Tang Yuk Ming , Keung Alan Leung Wai
Published: November 2023

In general, the elderly mainly face two kinds of problems, namely physical
and mental. Such kinds of problems lead to the unfolded challenges for the elderly in
the community. Also, it may increase the burden on the healthcare system in the long
term. To this end, this chapter introduces the adoption of mobile apps for the elderly to
increase the elderly social mobility and mitigate the overloaded public healthcare
system in the future.
Virtual Reality, Artificial Intelligence and Specialized Logistics in Healthcare
Authors: Lau Yui-yip , Tang Yuk Ming , Keung Alan Leung Wai
Published: November 2023

Virtual Reality, Artificial Intelligence and Specialized Logistics in Healthcare aims to enrich knowledge and expertise in the field of advanced technologies and specialized logistics within the healthcare industry. A key feature of the book is the focus on mitigating the effects of epidemics such as COVID-19.

The book offers a comprehensive understanding of these topics across nine chapters. The initial chapters, 1 and 2, meticulously delve into the state-of-the-art advancements in healthcare research. This section focuses on advances in immersive technologies (such as VR and AR), and internet of Things for digital healthcare services.

Chapters 3 and 4 cover specialized logistics, providing an in-depth exploration of funeral logistics and vaccine supply chains, respectively. The next chapter provides case-studies on community level anti-epidemic measures,

Chapters 6, 7, and 8 concentrate on pertinent issues concerning the elderly population. Topics in this section include elderly care home surveys. the utilization of modern mobile applications tailored for the elderly, and a comprehensive narrative review of mobile technology from the perspective of the elderly.

Lastly, Chapter 9 culminates the exploration by addressing the adoption of macro business simulation in healthcare products. Leveraging illustrative examples such as hand sanitizers, this chapter offers valuable insights into healthcare product adoption.

In essence, this book serves as a resource for policymakers, researchers, students, and industrial practitioners. References and summaries make this an indispensable guide for those seeking to navigate and comprehend the ever-evolving healthcare and supply chain industry.
Water Hyacinth Potential in The Pollution Impact Reduction of Coffee Agroindustry Wastewater
Authors: Elida Novita  , Sri Wahyuningsih  , Mastuki Andika  , Hendra Andiananta Pradana
Published: November 2023

Coffee processing wastewater originating from the coffee agroindustry has the potential to reduce environmental quality. Water hyacinth is one of the biological agents capable of reducing pollutants in wastewater through a rhizo-filtration mechanism in the phytoremediation process. The pollutant reducing ability of water hyacinth is limited so that the replacement of water hyacinth is one of the alternatives for optimizing the phytoremediation method. The purpose of this research was to compare the replacement time of water hyacinth to the decrease parameters namely turbidity, Biochemicals Oxygen Demand (BOD), Chemicals Oxygen Demand (COD), ammonia, and phosphate in the treatment of coffee processing wastewater using the phytoremediation method. The research stages consisted of water hyacinth acclimatization, determination of hydraulic resistance time, water hyacinth replacement time, and analysis of wastewater pollutant reduction. The density of water hyacinth used is 30 grams / L and the incubation time is 14 days. The results showed that the replacement of water hyacinth had a positive effect on improving the quality of coffee processing wastewater. The most water hyacinth replacement was on the 7th day. The percentage of turbidity parameters, Biochemicals Oxygen Demand (BOD), Chemicals Oxygen Demand (COD), ammonia (NH3-N), and phosphate (PO4-P) in the treatment of coffee processing wastewater with replacement of water hyacinth sequentially is 92.02%; 81.10%; 81.05%; 76.03% and 72.40%.
Application of Green Retrofitting Ready Mix Concrete Plant in Indonesia to Increase Financial Benefits and Reduce Environmental Issues: A Case Study
Authors: Ardiansyah Mohammad Kholis , Husin Albert Eddy , Amin Mawardi
Published: November 2023

Currently, the Indonesian government continues to encourage the realization of sustainable development. The green concept is a sustainable development trend in the construction material industry. The concrete industry plays a vital role as a supplier of concrete materials in construction, so its availability is essential. The role of concrete industry itself has a negative impact on the environment. Stakeholders increase the cost of green retrofitting so that the industry or building becomes eco-friendly. The research method was carried out using a process case study, namely, how to implement green retrofitting cost performance in the concrete industry using Value Engineering and Life Cycle Cost Analysis. Theoretically, the research results provide additional knowledge for academics; practitioners can provide problem-solving to get an overview of the implementation of the green concept in the industry regarding the flow of implementation and the benefits of savings in an environmentally friendly production process. The application of value engineering in the green retrofitting of the concrete industry has increased the cost performance of green retrofitting by 8.66% with a return of 3 years and 8 months and increased the functions and benefits of an eco-friendly and sustainable concrete industry
Contexto de cadena de guandul (Cajanus cajan)
Authors:   , Arenas Rubio Isueh , Moreno Medrano Dania , González Cerón Sandra Paola , Romero Perdomo Felipe Andrés
Published: November 2023

La cadena de guandul ofrece un panorama del comportamiento de este cultivo a nivel nacional e internacional. En ella, se abordan aspectos fundamentales como la producción, la cosecha y el rendimiento del guandul, lo cual permite tener una visión clara de su desempeño e impacto en la productividad agrícola. Además, se destacan otros aspectos como la generación de empleo en Colombia de este cultivo, que beneficia las comunidades locales. Asimismo, se resalta el costo total de producción asociado al guandul, lo que determina la competitividad de los precios y la rentabilidad para los agricultores colombianos
Risk Analysis of Sengon (Falcataria moluccana Miq.) Seedling Production Using Fault Tree Method
Authors: Yodfiatfinda Yodfiatfinda , Putri Fathiya Azzahra , Baksh Rukavina
Published: November 2023

This research analyzed the sengon (Falcataria moluccana Miq.) seedling production risk and factors associated with the risks at the Research and Development Center for Forest Plant Seed Technology (BPPTPTH) Bogor. The data collection included interviews using questionnaires with 11 purposely selected respondents. This research employed the Fault Tree Analysis (FTA), a descriptive qualitative method, to analyze the seedling production risks. The results revealed two groups of risks, namely field and management production risks, that stemmed from eight primary roots. These eight primary roots included long seed storage time, far distance between the nursery and the researcher's office, lack of safety facilities, lack of employee skills, lack of employee appreciation, high frequency of employee absences for personal reasons, changes in seasons that cause changes in planting schedules, and changes in budget allocation. Inaddition to these eight main factors, leaf aphids and fungi attacks, including tumorrust(karat puru), could also increase seedling production risks.
Cohabitation Study of Tricolour Langur (Presbytis chrysomelas ssp. cruciger) and Proboscis Monkey (Nasalis larvatus) in Bukit Semujan Danau Sentarum National Park
Authors: Santoso Nyoto , Diva Alfatheya Margwita , Fauziah Natasya Nurul , Sutopo Sutopo
Published: November 2023

The  tricolour langur and proboscis monkey in Bukit Semujan cohabited and utilized the same resources. Cohabitation, mainly due to resource constraints, needed substantial attention to ensure the survival of these primates. This research aimed to map the utilization of canopy strata vertical forest structure and vegetation as food sources and identify the size and overlap of ecological niches for both primates. This research occurred in Danau Sentarurn National Park (DSNP) from July to December 2021. The data collection employed the ad libitum method. The results indicated that cohabitation occurred in the canopy strata vertical forest structure utilization, particularly stratum B and C, and was related to food availability for both primates. The Jaccard Index of the stratum utilization association was 0.6 for swamp forests and 0.8 for hillside forests, while the food plant association was 0.2. In addition, the ecological niche of the  tricolour langur overlapped 48% against the proboscis monkey and 34% on the contrary. The tricolour langur's niche size (FT) was 0.32278 ≤ 0.5960 ≥ 0.81253, while the proboscis monkey was 0.20866 ≤ 0.52837 ≥ 0.78529 at 95% confidence interval.
MULTI-CRITERIA SELECTION OF STANDARDS FOR SYSTEM ANALYST ACTIVITIES IN ORGANIZATIONS
Authors: Rakić Miomir , Žižović Miodrag M. , Miljković Boža , Njeguš Angelina , Žižović Mališa R. , Đorđević Igor
Published: November 2023

The paper defines the methodology for the selection of standards and tools that system analysts use for the purposes of analyzing the computer infrastructure of organizations. The goal of system analyst analysis is primarily to increase: the speed of processing information, the efficiency of data processing and data exchange. A large number of standards and tools complicates an adequate choice, and on the other hand system analysts are not the only ones who influence the choice. In the analysis of the choice of standards and tools, in the second chapter an algorithm for determining the weight coefficients for the criteria selected by the company and the ranking of the standards for selection is presented through an example. In order to choose the best standard, the choice was made between four standards described in the third chapter. The chapter defines the criteria that cover IT activities for the selection of standards according to selected criteria and defined weight coefficients in the observed company. Finally, on the assumption that the company together with the analyst chose “k” criteria, where the methodology (LBWA) for the selection of weight coefficients for the criteria was proposed, a new model for calculating the ranking of standards was presented, i.e. the choice of the best. The conclusion of the paper is that the presented procedure for choosing standards is not complicated, that it is very successful, and that in this way the proposals were more easily accepted and implemented in the fastest way.
A HYBRID DEEP LEARNING APPROACH FOR SENTIMENT ANALYSIS IN PRODUCT REVIEWS
Authors: Kuang Minghui , Safa Ramin , Edalatpanah Seyyed Ahmad , Keyser Robert S.
Published: November 2023

Product reviews play a crucial role in providing valuable insights to consumers and producers. Analyzing the vast amount of data generated around a product, such as posts, comments, and views, can be challenging for business intelligence purposes. Sentiment analysis of this content helps both consumers and producers gain a better understanding of the market status, enabling them to make informed decisions. In this study, we propose a novel hybrid approach based on deep neural networks (DNNs) for sentiment analysis in product reviews, focusing on the classification of sentiments expressed. Our approach utilizes the recursive neural network (RNN) algorithm for sentiment classification. To address the imbalanced distribution of positive and negative samples in social network data, we employ a resampling technique that balances the dataset by increasing samples from the minority class and decreasing samples from the majority class. We evaluate our approach using Amazon data, comprising four product categories: clothing, cars, luxury goods, and household appliances. Experimental results demonstrate that our proposed approach performs well in sentiment analysis for product reviews, particularly in the context of digital marketing. Furthermore, the attention-based RNN algorithm outperforms the baseline RNN by approximately 5%. Notably, the study reveals consumer sentiment variations across different products, particularly in relation to appearance and price aspects.
Isolation and Identification of Shimwellia blattae from the Gut of the Hospital Cockroach Blatta orientalis in Annaba City, Algeria
Authors: Benouagueni Sarah , Labid Asma , Mehainaoui Aida , Kirane Djamila Gacemi
Published: November 2023

The overall aim of this paper was to divulge the pathogenic and beneficial bacterial flora of cockroaches (Blatta orientalis) living in a hospital area in Annaba city, Algeria. Thirteen cockroaches were randomly apprehended in sterile conditions during March 2022 in two different hospitals in Annaba, “El Bouni” Hospital and the “Sainte-Therese” Hospital. Bacterial strains were isolated from the imprint of the insect on Petri dishes previously inoculated with different media, also from external and internal body part suspensions of the captured specimens. Biochemical identification was established using the analytical profile Index (API) System (Biomerieux, France). The identification of the enteric-screened strain was confirmed using molecular sequencing of the 16S rRNA gene and phylogenetic analysis was performed. The results showed a high prevalence of the pathogenic strains isolated from the oriental cockroach Blatta orientalis (225 strains), such as Serratia liquefaciens, Raoultella ornithinolytica, Pseudomonas luteola, Enterobacter aerogenes, Hafniaalvei and Bacillus sp. Phylogenetic analysis of the enteric bacteria confirmed the affiliation with Shimwellia blattae NCTC10965 (100%), Basonym Escherichia blattae, which is a natural cyanocobalamin producer. Results confirm at the same time the symbiotic relationship between S. blattae and Blatta orientalis, but also point out the underrepresented potential of these insects as a source of strains with biotechnological interest.
Las villas de Cartagena y su caracterización cultural. Una visión de conjunto
Authors: NAVARRO MORENO David
Published: November 2023

Cartagena conserva un interesante grupo de villas burguesas construidas a finales del s.XIX con una sofisticada arquitectura y jardinería. Desafortunadamente constituye un patrimonio cultural poco estudiado y en riesgo de desaparición. El objetivo de esta investigación es identificar, describir y analizar dichas villas para ofrecer una visión panorámica. La metodología ha consistido en el acercamiento a las mismas mediante su inventario y catalogación, seguido del análisis comparativo entre ejemplares. Los resultados constatan el valor cultural del conjunto de villas por la multiplicidad de valores que agrupan, relacionados tanto con la arquitectura, jardinería y paisajismo, como con la antropología y etnografía.
PROSPECT OF MINERAL AND COAL MINING POLICY
Authors: Pertiwi Rahni Andeka , Manik Berliandy Haposan , Praditha Azzahra Ayu , Safitri Nur
Published: November 2023

Mineral and coal mining policy is a subject that continues to receive attention in the legal and regulatory environment. This journal analyzes prospective mineral and coal mining policies through a normative juridical approach focusing on relevant regulatory aspects and legal implications. This study uses a normative juridical analysis method to evaluate policies that apply in the context of mineral and coal mining. This research gains an in-depth understanding of the existing regulatory structure by reviewing applicable laws and regulations, court decisions, and decisions of regulatory agencies. The results of this study indicate that mineral and coal mining policies have a solid legal basis and regulate various aspects, such as licensing, environment, labor protection, and corporate social obligations. However, there are challenges related to law enforcement, harmonization of regulations, and consistent implementation of policies. In response to these challenges, this study proposes several recommendations to increase the effectiveness of mineral and coal mining policies legally. These recommendations include expanding cooperation between relevant government agencies, improving regulations and procedures, increasing legal capacity, and strengthening oversight and stricter law enforcement. This research is expected to contribute to policymakers, legal practitioners, and related parties in developing more responsive, comprehensive, and effective regulations in maintaining the sustainability of the mineral and coal mining sector by taking into account related legal aspects.
LOCAL GOVERNMENT POLICY IN EMPOWERING WOMEN IN HOUSEHOLD WASTE MANAGEMENT
Authors: Jufri Billy A , Raksanjani Reyhan , Badri M.Hilalatul , Ahdim Haddad P , Siboro Daniel S
Published: November 2023

Waste is the residue of human daily activities and natural processes in solid form. The waste production rate continues to increase, not only in line with population growth but also with the increasing consumption patterns of society. On the other hand, the waste management capacity conducted by both the community and local government still needs to be optimal. This research uses a normative juridical research method with a legal research approach. It employs standards using a literature review. The literature review in this research is based on legislation, books, journals, academic news media, and online sources. This research uses The legal approach to explore possible concepts and techniques. This normative legal research aims to find a general legal model for rationalizing natural resources. The Organic Village activities begin with meetings and planning within community groups at the Dasa Wisma level. In the Dasa-Wisma group meetings, a routine program is developed to conduct weekly organic and inorganic waste inventories. The challenges faced in the field are analyzed, and alternative solutions are considered. The Legok Makmur Organic Village activities start with meetings and planning within community groups at the Dasa Wisma level. The Legok Makmur activities carried out by the community association include daily organic waste counting, plant watering, processing of shredded organic waste every Sunday around noon, and receiving sales proceeds of inorganic waste from residents in exchange for goods. These topics include environmental maintenance, collaboration with club administrators, harvests, member shopping, external group members, vegetable cultivation, and poultry and fish farming. The community has the right and equal opportunity to think and actively participate in disaster management and environmental management.
A nine-year (2012-2020) study of publication delay in an open access Library and Information Science journal
Authors: (Corresponding Author) Sandip Majumdar (Corresponding Author)
Published: November 2023

This study attempts to map the publication delay of articles published in an international, peer-reviewed, open access Library and Information Science journal (LIS) i.e. the DESIDOC Journal of Library and Information Technology (DJLIT). An exploratory method was applied to collect data related to the editorial timeline through archival open access to the articles published in DJLIT during the period from 2012 to 2020. Data were tabulated in an Excel spreadsheet to facilitate statistical analysis and interpretation. The study finds a mean and median waiting time of approximately 176 days and 152 days respectively for articles before they got published. About 64.57 percent of articles went through revision. The majority of articles (i.e., 40.08%) experienced a delay between 100-199 days and were closely followed by 26.11 percent of articles with a delay of up to 99 days. Only 2.43 percent of articles fell in the 400-499 days delay category before being published. A strong influence of time between submission to final revision on overall publication delay was observed. The study did not find any correlation between the number of contributing authors and increasing delay in publication and contradicts the result obtained in another study on selected information science journals. The study is expected to help researchers and authors in the field of LIS to take informed decision before submitting their manuscripts to DJLIT for publication.
Profiling COVID-19 research in the social sciences from Indonesia based on Scopus database
Authors: - Yusnaini, , - Nengyanti , Yanti Mery , (Corresponding Author) Anang Dwi Santoso
Published: November 2023

This study provides insights into the pattern of COVID-19 research publications in Indonesia and aims to map out the contributions of social science scholars in the country during the pandemic, using bibliometric analysis. The analysis was conducted through desk research using the scientometric method from the Scopus database, with a total of 1,037 articles analysed. The research found that social sciences scholars in Indonesia made significant contributions to the fields of online learning, economics, business and management, public health and administration, and communication and media studies. The study also identified the influences of research areas, funding, open access, female first author, female co-authors, and international collaborative research on quartile and the number of citations. The implications of the study suggest that efforts should be made to promote gender diversity in research, allocate research funding appropriately, and encourage international collaboration. Authors should prioritize publishing in high quartile journals and opt for open access publication. Additionally, academic institutions and funding agencies should provide guidance on selecting reputable journals to maintain a culture of quality research.
Mastectomia preventiva em situações de câncer de mama precoce.
Authors: Coelho Verena Isabelle , Chagas Jaqueline Maria de Azevedo , Costa Fernando Henrique da Silva , Azevedo João Victor Bezerra de Moura , Maciel Kailane Luiza , Mühlmann Lindson , China Mayara Jéssica Monteiro , Morais Rainally Sabrina Freire de , Amer Shadya Teixeira , Mendonça Virgílio Dias Furtado , Zanoni Rodrigo Daniel
Published: November 2023

Introdução: A mastectomia preventiva relacionada às neoplasias de mama precoces é um tema de grande importância na área da oncologia, especialmente para mulheres com alto risco genético de desenvolver câncer de mama. Objetivo: Descrever como a mastectomia relaciona-se com a prevenção de neoplasias de mama precoces. Pergunta: O que a literatura científica dispõe acerca da mastectomia preventiva relacionada às neoplasias mamárias em idade precoce? Métodos: Trata-se de uma revisão integrativa da literatura, por proporcionar uma síntese dos resultados obtidos através de pesquisas publicadas. Para construção da pesquisa, a coleta e análise de dados foi realizada através do Portal da Biblioteca Virtual da Saúde e da base de dados Medical Literature Analysis and Retrievel System Online via PubMed, através dos seguintes Descritores em Ciências da Saúde (DeCS): “Mastectomia Profilática”, “Neoplasias da Mama” e “Fatores de Risco” combinados entre si pelo operador booleano AND. Resultados: A mastectomia preventiva relacionada às neoplasias de mama precoces é um tema amplamente discutido no campo da oncologia. Essa intervenção cirúrgica, que envolve a remoção preventiva da mama saudável em mulheres com alto risco genético de desenvolver câncer de mama, tem gerado debates e opiniões divergentes. Conclusão: A mastectomia preventiva relacionada às neoplasias de mama precoces é uma opção terapêutica complexa e individualizada, que busca reduzir o risco de desenvolvimento ou recorrência do câncer de mama em mulheres de alto risco.
The efficacy of two models – MEAF and pMELD, as indicators of lethal outcome in early postoperative period after liver transplantation in children
Authors:   University Hospital “Lozenetz”, Sofia University “St. Kliment Ohridski”, Sofia, Bulgaria, Goncharov Andrey , Uzunova Yordanka
Published: November 2023

The current study is aiming to prove the effectiveness and compare “Model for Early Allograft Function” (MEAF) and “postoperative Model for End-stage Liver Disease” (pMELD) in the early posttransplant setting in children. Methods. We did a retrospective study on 43 liver transplant patients for a 17-year period between the ages 0 – 18 years. MEAF and pMELD were calculated on the third and fifth postoperative day, respectively, and a Cox regression analysis was performed to find the correlation between them and mortality in the early postoperative period (EPOP). Results. Both scores proved to be statistically significant and applicable in EPOP. MEAF had P value of 0.0003 and a hazard ratio of 10.99, while pMELD demonstrated P value of 0.003 and a hazard ratio of 1.24. Conclusions. Both MEAF and pMELD can be used for the diagnostics of early allograft dysfunction and predicting the outcome of the transplantation, with MEAF having the upper hand.
Privacy-preserving WiFi-based Crowd Monitoring
Authors: Rusca Riccardo , Carluccio Alex , Casetti Claudio , Giaccone Paolo
Published: November 2023

The process of estimating the number of individuals within a
defined area, commonly referred to as people counting, is of
paramount importance in the realm of safety, security and crisis
management. It serves as a crucial tool for accurately monitoring crowd
dynamics and facilitating well-informed decision-making during critical
situations. In our current study, we place a special emphasis on the
utilization of the WiFi fingerprint technique, leveraging probe request
messages emitted by smart devices as a proxy for people counting.
However, it is essential to recognize the evolving landscape of privacy
regulations and the concerted efforts by major smart-device
manufacturers to enhance user privacy, exemplified by the introduction
of MAC addresses randomization techniques. In this context, we designed
a crowd monitoring solution that exploits Bloom filters for ensuring a
formal deniability, aligning with the stringent requirements set
forth by regulations like the European GDPR [1] . Our
proposed solution not only addresses the essential task of people
counting but also incorporates advanced privacy-preserving mechanisms.
Importantly, it seamlessly integrates with trajectory-based crowd
monitoring, offering a comprehensive approach to managing crowds while
respecting individual privacy rights.
Phenological synchrony does not regulate fecundity in a mast-fruiting oak species
Authors: Sork Victoria , Lentz Andy , Davis Frank
Published: November 2023

Biologists have long debated why some plant species produce many seeds
synchronously during some years and few during others. One hypothesis is
that selection on phenological synchrony of flowering improves
pollination efficiency and leads to increased fecundity. In an 11-year
study of valley oak (Quercus lobata), we found that, indeed,
trees that produced flowers during mid-season tended to produce more
acorns. But, is synchrony the key factor? Here, we test the phenological
synchrony hypothesis versus the alternative hypothesis that the
environment principally shapes flowering phenology and acorn production.
At our site, we find that a tree’s microenvironment is associated with
both timing of phenology and acorn production. Timing of flowering
depends on air temperature and crop size is not related to synchrony but
is best predicted by relative elevation – likely a proxy for substrate
quality and access to water. We conclude that microenvironment - not
phenological synchrony - shapes acorn production.
Reduced Post-Ablation Chest Pain with Active Esophageal Cooling
Authors: Zagrodzky William , Small Allison , Joseph Christopher , Cooper Julie , Kulstad Erik , Brumback Babette , Aslam Kamran
Published: November 2023

Introduction: Post-ablation chest pain is a common occurrence
in patients after radiofrequency (RF) pulmonary vein isolation (PVI)
ablation for the treatment of atrial fibrillation (AF), with a reported
incidence of up to 50%. Pain can be caused by pericarditis, vagal
plexus thermal injury, gastroparesis, or local inflammation. Active
esophageal cooling is FDA cleared for reducing the likelihood of
ablation-related esophageal injury resulting from RF cardiac ablation
procedures, but cooling has also been reported to have pleiotropic
effects which may mitigate inflammation and reduce the likelihood of
post-ablation chest pain. The aim of this study is to quantify the
change in incidence of post-ablation chest pain after the adoption of
active esophageal cooling during RF ablations. Methods: Data
from a community hospital registry were obtained for the 12 months prior
to (pre-adoption), and the 12 months after adoption (post-adoption) of
active esophageal cooling in December 2021 during RF ablations. Type of
ablation was recorded, along with patient’s age, post-ablation symptoms,
and type of prophylactic treatment utilized. Incidence rates of chest
pain before and after adoption of esophageal cooling were then compared.
Results: Data were reviewed from 183 patients. In the
pre-adoption cohort, patients were given 2 weeks of daily sucralfate and
pantoprazole, with an additional 4 weeks in cases with persisting
symptoms. In this group, 90 patients (66.7% persistent AF) with a mean
age of 69.6 years (SD ± 10.34) received PVI, with 62 (68.9%) receiving
roof lines, 60 (66.7%) receiving floor lines, and 41 (45.6%) reporting
post-ablation chest pain requiring extension of treatment to 6 weeks. In
the post-adoption cohort, 2 days of sucralfate and pantoprazole was
given, and a total of 93 patients (75.2% persistent AF) with a mean age
of 68.3 years (SD ± 10.28) received PVI, with 79 (84.5%) receiving roof
lines, 75 (80.6%) receiving floor lines, and none reporting
post-ablation chest pain (p<0.0001). Conclusion:
Adoption of active esophageal cooling was associated with a significant
reduction in post-ablation chest pain despite increased use of posterior
wall isolation and decreased use of prophylactic treatment.
Age-related changes of the time-varying features in the brain functional connectivity and cognitive ageing
Authors: Yao Furong , Zhao Ziyang , Wang Yin , Li Tongtong , Chen Miao , Zhijun Yao , Jiao Jin , Hu Bin
Published: November 2023

Brain functional modular organization changes with age. Considering the
brain as a dynamic system, recent studies have suggested that
time-varying connectivity provides more information on brain functions.
However, the spontaneous reconfiguration of modular brain structures
over time during ageing remains poorly understood. In this study, we
investigated the age-related dynamic modular reconfiguration using
resting-state functional MRI data (615 participants, aged 18-88 years)
from Cam-CAN. We employed a graph-based modularity analysis to
investigate modular variability and the transition of nodes from one
module to another in modular brain networks across the adult lifespan.
Results showed that modular structure exhibits both linear and nonlinear
age-related trends. The modular variability is higher in early and late
adulthood, with higher modular variability in the association networks
and lower modular variability in the primary networks. In addition, the
whole brain transition matrix showed that the times of transition from
other networks to the dorsal attention network were the largest.
Furthermore, the modular structure was closely related to the number of
cognitive components and memory-related cognitive performance,
suggesting a potential contribution to flexibility cognitive function.
Our findings highlighted the notable dynamic characteristics in
large-scale brain networks across the adult lifespan, which enhanced our
understanding of the neural substrate in various cognition during
ageing. These findings also provided further evidence that
dedifferentiation and compensation are the outcomes of functional brain
interactions.
How ADB Uses Futures and Foresight Tools to Help Countries Prepare for an Uncertain Future
Authors:   Asian Development Bank, Roth Susann , Parry Jane ,   Asian Development Bank
Published: November 2023

As ADB’s developing member countries target sustainable growth and tackle inequality, this brief shows how future-focused tools and approaches can lead to forward-thinking strategies designed to navigate climate change and digital transformation. It outlines how ADB is expanding beyond knowledge management to help countries identify emerging issues, understand their consequences, and develop scenarios. Providing examples of different analyses, the brief explains the importance of integrating technology, data, and people to create effective policies and strategies that can foster innovation and better prepare countries to tackle the complex development challenges of the future.
Ekonomiczno-ekologiczne aspekty wdrożenia zestawów klasy LHV-LZV do obsługi łańcuchów dostaw w ramach ciężkiej dystrybucyjnej logistyki ostatniej mili w miastach – przykład Holandii
Authors: Brach Jarosław
Published: November 2023

Koncepcja wydłużonego miejskiego zestawu klasy City LZV-LHV jest w Polsce prawie zupełnie nieznana, głównie ze względu na prawny brak możliwości wprowadzenia zestawów tego rodzaju na nasze drogi. Niemniej zestawy te – o czym dobitnie świadczy przypadek Holandii – mogą się przyczynić do znacznej poprawy konkurencyjności ciężkiej dystrybucji w miastach. Cel tego artykułu polega więc na wskazaniu na korzyści organizacyjno-czasowe, ekonomiczne oraz ekologiczne związane z wdrażaniem zestawów tego rodzaju. Postawiono tezę, że jeżeli przepisy prawa na to pozwalają oraz istnieją operatorzy mogący zapewnić opłacalność tego rozwiązania, co wynika z konieczności zabezpieczenia w danym czasie odpowiedniej masy towarowej przeznaczonej do dystrybucji na danym obszarze miasta, to wtedy propozycja ta wykazuje pełny sens wdrożeniowy. Podstawę dla artykułu stanowiła analiza materiałów źródłowych, zasadniczo pochodzących od holenderskich instytucji rządowych, instytutów badawczych, operatorów transportu producentów odpowiedniego sprzętu przewozowego oraz sieci handlowych. Uzupełniły to własne wnioski i przemyślenia autora wynikajace z analizy tego narzędzia w systemie łańcuchów dostaw w miastach.
Wpływ pandemii koronawirusa na mobilność Polaków
Authors: Stec Sławomir
Published: November 2023

Trwająca od 2020 roku pandemia COVID-19 spowodowała bardzo duże zmiany w wielu dziedzinach życia na całym świecie. Zaistniałe zmiany dotknęły bezpośrednio całe społeczeństwo. W miarę wzrostu liczby zakażeń i rozprzestrzenianiu się patogenu po całym świecie, zaczęła spadać mobilność społeczeństwa. W związku z powyższym podjęto badania, których celem było przeprowadzenie oceny wpływu pandemii COVID-19 na mobilność mieszkańców Polski, a w szczególności przeprowadzanie diagnozy w zakresie siły wpływu liczby zakażeń na mobilność pieszą i pojazdami mieszkańców Polski. Do badań wykorzystano metodę współczynnika korelacji liniowej Persona. W wyniku analiz, stwierdzono, że w całym badanym okresie, od 1 marca 2020 roku do 31 grudnia 2021 roku wzrost liczby zakażeń umiarkowanie wpływał na spadek mobilności mieszkańców. Najbardziej silną zależność odnotowano w pierwszych dwóch tygodniach pandemii. W tym, okresie współczynnik korelacji wynosił –0,845 dla mobilności pieszej i –0,895 dla mobilności pojazdami. Wraz z upływem czasu, kiedy ludzie zaczęli się oswajać z pandemią, a także rozpoczęto szczepienia przeciwko COVID-19, zależność między liczba zakażeń, a mobilnością społeczeństwa zmniejszyła się z silnej do umiarkowanej.
Rozwój systemów kolejowego transportu pasażerskiego w krajach Grupy Wyszehradzkiej i krajach bałtyckich
Authors: Wilczewska Martyna
Published: November 2023

Celem badania była ocena rozwoju krajowych systemów kolejowego transportu pasażerskiego Estonii, Łotwy, Litwy, Polski, Czech, Słowacji i Węgier na tle rezultatów osiąganych na poziomie całej UE w kontekście realizacji europejskich celów związanych ze zrównoważeniem europejskiego systemu transportowego. Badanie obecnego stanu oraz przyszłych perspektyw rozwoju europejskiego systemu transportu kolejowego stanowi istotne zagadnienie badawcze, szczególnie w kontekście przemian zachodzących w europejskim systemie transportowym. W badaniu zastosowano metodę TOPSIS, przy wykorzystaniu danych statystycznych publikowanych przez Eurostat, Komisję Europejską oraz IRG-Rail. W jej wyniku zbudowano cztery rankingi odzwierciedlające relatywne rezultaty osiągane przez systemy transportowe analizowanych krajów w latach 2005, 2010, 2015 i 2020. Wyniki badania wskazują, że w latach 2005 i 2010 jedynie Czechy i Węgry osiągały rezultaty powyżej średniej UE, w 2015 i 2020 roku natomiast udało się to również Słowacji. W analizowanym okresie cztery spośród siedmiu krajów (oprócz Węgier, Łotwy i Litwy) notowały regularny postęp aż do roku 2015, po czym w 2020 roku nastąpiła stagnacja lub spadek względnych rezultatów wszystkich krajów poza Węgrami. Przesunięcie modalne na transport kolejowy ma być jednym z kluczowych środków mających umożliwić realizację europejskich polityk dotyczących zrównoważonego rozwoju i osiągnięcie do 2050 roku neutralności klimatycznej, co czyni badanie tej gałęzi transportu istotnym narzędziem wspierania podejmowania decyzji rozwojowych.