bluuebunny/crossref_metadata_2025 huggingface dataset:
Safe use of opioids
Authors: Go Se-Il , Won Young-Woong , Kang Jung Hun
Published: January 2022

Background: Opioids are effective analgesics for cancer pain and refractory non-cancer pain. Although they are essential medication, problematic issues on aberrant behavior and adverse events have rapidly emerged as social problems in Korea. This study aimed to describe the mechanisms, efficacy, and adverse events, especially how to deal with opioid dependency.Current Concepts: Opioid-induced aberrant behavior includes physical and psychological dependences (addiction), abuse, and diversion (giving prescribed opioids to another person). Most physicians are unfamiliar with how to handle patients presenting these problematic issues. Physical and psychological dependences develop through different pathophysiologic mechanisms, i.e., noradrenergic and dopaminergic pathways, respectively. Motivational enhancement therapy, psychosocial support, substitution therapy with buprenorphine, and adjunctive medications, including alpha-2 adrenergic agonist, antidepressants, and non-steroidal antiinflammatory drugs, are the mainstay of treatment for opioid dependency. Constipation, nausea/vomiting, drowsiness/sedation, delirium, itching sensation, voiding difficulty, dry mouth, opioid-induced hyperalgesia, and respiratory depression are well-known physical side effects of opioid consumption.Discussion and Conclusion: Research on the development history, epidemiology of opioid dependency, and its treatment are warranted to avoid an opioid crisis in Korea. Above all, thorough knowledge for physicians and patients is urgently needed.
Doctors’ consciousness on CCTV installation in operating rooms: A survey
Authors: Lim Ji Yeun , Lim Sun Mi , Kim Kye-Hyun
Published: January 2022

Background: A bill for the mandatory installation of closed-circuit television (CCTV) in operating rooms, still likely in breach of the constitution, was approved. When a bill infringing on individuals’ fundamental rights is drafted, alternative means of minimizing the infringement of the offender’s rights should be considered ahead of the draft. To this end, alternatives on the bill identified through the consciousness of the offender would be most realistic and much more effective. Thus, this study examined doctors’ consciousness on the mandatory installation of CCTV in operating rooms, the appropriateness of punishment for members who commit immoral and unethical behaviors, and doctors’ alternative ideas to CCTV installation in operating rooms.Methods: The online survey was conducted for a week from July 9, 2021, to July 16, 2021, by the Korean Medical Association Doctors News, and 2,345 doctor members responded to the investigation.Results: According to the survey, the following alternatives to CCTV installation in operating rooms were proposed: strengthening punishment for performing ghost surgery (38.3%), placing cameras at the entrance of the operating room (21.8%), mandatory written consent (pledge) (13.7%) to prevent ghost surgery for medical staff participating in the surgery, promoting self-purification (whistle-blowing) (11.5%), and a biometrics function for entering operating rooms (8.8%).Conclusion: The revised medical law delegated legislative devices to subordinate statutes for minimizing infringement. Thus, new regulations should be set to reduce infringement of fundamental rights. It is hoped that doctors’ consciousness on new law could be preliminary data to regulate new rules in discussing lower statutes.
“Replete with instruction and rational amusement”?: Unexpected Features in the Register of British Didactic Novels, 1778–1814
Authors: Misset Juliette
Published: January 2022

British didactic novels of the turn of the 19th century have been defined as works of fiction where instruction in moral codes of behavior rather than imaginative elements is the primary focus (Havens 2017, p. 5). My research aims to investigate the generic specificities of such novels by working with the open-source software TXM and AntConc to compare two corpora of novels published between 1778 and 1814 in Britain. These corpora were created using reviews from the Monthly Review and the Critical Review. Contrary to my hypothesis, a lexical comparison of the two corpora shows that the novels they contain do not materially differ in their use of lexis related to instruction and morality. This leads me to reassess the basis for the early reception of didacticism in these novels. Fruitful new hypotheses are generated using both corpus stylistics and close reading.
Aquela Noite: o lugar da Israel imaginária na nova direita brasileira
Authors: Gherman Michel
Published: January 2022

Neste artigo, oferecemos uma reflexão sobre o significado dos símbolos judaicos e sionistas contexto político contemporâneo do Brasil. Pretendemos aqui explorar os significados do aparecimento destes símbolos em manifestações e da ‘Nova Direita’ brasileira. Pretendemos aqui entender as relações de tais símbolos com grupos conservadores no país. Além disso, também buscamos refletir sobre a mudança de significado da raça no Brasil após a realização da Conferência de Durban em 2001e suas consequencias para a população judaica residente no país.
CISNE, Mirla. 2018. Feminismo e Consciência de Classe no Brasil.
Authors: Souza Jheuren Karoline Costa de
Published: January 2022

Mirla Cisne possui sua formação voltada ao Serviço Social tanto em nível de graduação, quanto mestrado e doutorado. Neste livro, Feminismo e Consciência de Classe no Brasil, retoma seu trabalho de doutorado realizado sobre os principais movimentos de mulheres do Brasil (Articulação de Mulheres Brasileiras, Movimento de Mulheres Camponesas e Marcha Mundial das Mulheres), trazendo importante análise para se pensar e questionar a importância da consciência de classe nos movimentos feministas do país.
Informação – um Produto Insubstituível na Estratégia de Marketing: Estudo de Caso Empresa E-Commerce
Authors: Seguro José Leandro , Razzolini Filho Edelvino , Franco Everton De Barros
Published: January 2022

Este artigo objetiva analisar de que forma uma empresa de e-commerce, localizada em Curitiba-PR, coletam dados e como os transforma em informações úteis para construção da estratégia de marketing. O estudo tem cunho qualitativo, por meio de uma revisão bibliográfica de artigos sem corte temporal, estudo de caso único por meio de entrevista semiestruturada, com a finalidade de descrever um evento contemporâneo específico. Como resultado do estudo, foi constatado que a principal fonte de dados internos são os históricos de vendas. Por outro lado, como fontes externas, a empresa monitora informações de sítios de internet de empresas concorrentes. Após transformarem esses dados em informações, a empresa realiza seu planejamento e define sua estratégia de marketing, direcionando os anúncios e suas promoções, reduzindo os custos da operação e maximizando os resultados.
Monitoring of biochemical parameters of the oral fluid in patients with recancerous of the oral mucosa
Authors: Kontorshchikova Klavdiia Nikolaevna , Kazarina L. N. , Gulyan U. G. , Pursanova A. E. , Zakharova A. R. , Kontorshchikov M. M. , Gushchina O. O.
Published: January 2022

Orthopedic treatment is of particular difficulty in the complex therapy and rehabilitation of patients with precancerous diseases of the oral mucosa. In this regard, in patients with chronic inflammatory and destructive lesions of the oral mucosa, it is necessary to control changes in the oral cavity, taking into account clinical and laboratory data. Oral fluid is most often used as a diagnostic material in dental research, the composition and properties of which reflect functional changes in the body. However, the studies that substantiate rational orthopedic treatment in such patients are extremely insufficient: there are no data on the effect of orthopedic structures on the primary metabolism in the oral cavity in patients with precancerous diseases. In this regard, the purpose of this work was to study the biochemical parameters of the oral fluid in patients using orthopedic structures to identify the prognostic factors of precancerous conditions. In the oral fluid, the levels of total protein, total cholesterol, triglycerides, and lactate were determined. Free radical oxidation was assessed by the intensity of induced biochemiluminescence and by the levels of lipid peroxidation products. In the oral fluid of patients with mucosal precancer compared with patients in the control group, a significantly higher intensity of free radical oxidation was revealed with a corresponding decrease in antioxidant activity. The level of the end products of lipid peroxidation - Schiff’s bases - was statistically significantly increased. Among the metabolites of the oral fluid, there was a decrease in protein levels and an increase in cholesterol and lactate levels. At the same time, a positive correlation was established between the indicators of free radical oxidation and lactate, free radical oxidation and cholesterol, but negative with the levels of protein and triglycerides. Regarding the antioxidant system, there was a negative correlation between the tg (-2α) value and the lactate level and positive with the triglyceride level, as well as a positive correlation between the Z parameter and the total protein level. The obtained changes in the biochemical parameters of the oral fluid can be used to confirm the diagnosis of precancer of the oral mucosa in patients with orthopedic structures.
Emerging Pan-Asian Identities in Chile in #StopAsianHate
Authors: Chan Carol
Published: January 2022

This position paper highlights the emergence of "Asian Chilean" identities and "anti-Asian racism" discourses during #StopAsianHate social media campaigns in Chile. We argue that while panethnicity can critically respond to and visibilise the shared racialisation of ethnic Chinese and Asian persons in South American contexts, public discussions must also distinguish between ethnic Chinese persons, Chinese-owned private and state enterprises, and the PRC government, as well as highlighting the diversity within these groups and others often considered as “Chinese” in Latin America. Both approaches are necessary to apprehend the multifaceted implications of geopolitical shifts in the region without promoting biased anti- or pro-China attitudes.
Strange New (Old) Worlds: Chinese Identities in Port Cities
Authors: Abe Kaori
Published: January 2022

Observers of migratory Chinese in port cities have been producing writings that highlight the diversity of “Chinese” identities and lifestyles throughout collecting micro stories of individuals. Simultaneously, their publications ­­––newspaper, magazines, and encyclopaedia––functioned as a transnational platform linking different Chinese communities in different locations.
Disrupted Nationality: Revisiting ‘Chinese’ in the Era of “Stop Asian Hate”
Authors: Du Yunpeng
Published: January 2022

Drawing on a two-year ethnography focused on the transnational academic trajectories of Chinese international students in London, I provide a ground-driven account of how Chinese nationality was consistently enacted, negotiated, and contested in the pandemic crisis such that it reshaped the everyday experiences of these students as oversea Chinese. As such, I shift attention to the real-life complexities, as well as the emerging inequality associated with national categories which were rendered as insignificant under the trending discourses of “Stop Asian Hate”.
UN ANÁLISIS CRÍTICO DE LA INTERNACIONALIZACIÓN Y LAS RELACIONES LABORALES EN LA INDUSTRIA AGROALIMENTARIA
Authors: Cardoso Ribeiro Bernardo , Guerra Costa Gabriel de Menezes , dos Santos Fernandes Jéssica , Siqueira Ribeiro Stephanie Caroline , de Carvalho Italo Brener
Published: January 2022

La internacionalización del sector agroindustrial alimentario es una cadena compleja y dinámica. Es necesario un análisis crítico de las influencias macroeconómicas, políticas, legales y socioculturales relevantes sobre los lineamientos estratégicos globales y la gestión de cadenas multinacionales en un sector fuertemente ligado a países emergentes. Este ensayo, a través de una metodología de análisis crítico, busca señalar en el contexto internacional: (1) la planificación y el ingreso a los mercados externos, (2) la internacionalización y organización del sector agroalimentario, en los mercados emergentes y finalmente presente a través de (3) una crítica a las relaciones laborales en el sector agroalimentario y su cadena global. Como resultado de este trabajo, se presentan los principales actores destacados como mercados y eslabones fuertes en la cadena productiva Brasil, Rusia, India y China, y las hipótesis que sugieren los vacíos a ser llenados por estudios futuros de importantes factores de investigación como la organización, estrategias y relaciones laborales presentes en la cadena global.
PRÁTICA DOCENTE NO ENSINO SUPERIOR: CONSTRUÇÃO FORMATIVA E DESAFIOS NO CONTEXTO DO BACHARELADO EM ADMINISTRAÇÃO
Authors: Massuga Flavia , Soares Simone , Luis Kuzma Edson , Pacheco Dos Santos Wanda Terezinha , Dias Doliveira Sergio Luis
Published: January 2022

O objetivo do estudo é compreender o processo de construção da prática docente universitária dos professores do curso de Administração de uma Universidade Estadual do Paraná, bem como apresentar uma perspectiva atual de sua prática, os desafios inerentes ao cotidiano da profissão e a percepção quanto à contribuição das disciplinas ou outros espaços formativos para a atuação docente. Aplicou-se entrevista estruturada a cinco docentes do referido curso, tratadas por meio de análise de conteúdo. As disciplinas e outros espaços formativos foram apontadas como essenciais no deslocamento da teoria para a práxis na administração, fatores consideravelmente associados à experiência adquirida no mercado e na prática docente. Ademais, a formação continuada ganhou destaque meio ao contexto complexo e mutável de aprendizagem.
Oceanographic regional climate projections for the Baltic Sea until 2100
Authors: Meier H. E. Markus , Dieterich Christian , Gröger Matthias , Dutheil Cyril , Börgel Florian , Safonova Kseniia , Christensen Ole B. , Kjellström Erik
Published: January 2022

Abstract. The Baltic Sea, located in northern Europe, is a semi-enclosed, shallow and tideless sea with seasonal sea-ice cover in its northern sub-basins. Its long water residence time contributes to oxygen depletion in the bottom water of its southern sub-basins. In this study, recently performed scenario simulations for the Baltic Sea including marine biogeochemistry were analysed and compared with earlier published projections. Specifically, dynamical downscaling using a regionally coupled atmosphere–ocean climate model was used to regionalise four global Earth
system models. However, as the regional climate model does not include
components representing terrestrial and marine biogeochemistry, an additional catchment and a coupled physical–biogeochemical model for the
Baltic Sea were included. The scenario simulations take the impact of various global sea level rise scenarios into account. According to the projections, compared to the present climate, higher water temperatures, a shallower mixed layer with a sharper thermocline during summer, less sea-ice cover and greater mixing in the northern Baltic Sea during winter can be expected. Both the frequency and the duration of marine heat waves will increase significantly, in particular in the coastal zone of the southern Baltic Sea (except in regions with frequent upwellings). Nonetheless, due to the uncertainties in the projections regarding regional winds, the water cycle and the global sea level rise, robust and statistically significant salinity changes could not be identified. The impact of a changing climate on biogeochemical cycling is predicted to be considerable but still smaller than that of plausible nutrient input changes. Implementing the proposed Baltic Sea Action Plan, a nutrient input abatement plan for the entire catchment area, would result in a significantly improved ecological status of the Baltic Sea, including
reductions in the size of the hypoxic area also in a future climate, which
in turn would increase the resilience of the Baltic Sea against anticipated
climate change. While our findings regarding changes in heat-cycle variables mainly confirm earlier scenario simulations, they differ substantially from earlier projections of salinity and biogeochemical cycles, due to differences in experimental setups and in input scenarios for bioavailable nutrients.
Investigating the effects of herbaceous root types on the soil detachment process at the species level
Authors: Wang Jian-Fang , Wang Bing , Yang Yan-Fen , Liu Guo-Bin , Zhang Feng-Bao , Fang Nu-Fang
Published: January 2022

Abstract. The changes in soil properties and root traits caused by plant growth might have great effects on the process of soil detachment by overland flow. On this basis, two typical herbaceous plants, Bothriochloa ischcemum (Linn.). Keng (BI; fibrous root system) and Artemisia vestita Wall. ex Bess (AG; tap root system), from the Loess Plateau were studied for one year under six planted densities of 5 plants m−2, 10 plants m−2, 15 plants m−2, 20 plants m−2, 25 plants m−2, and 30 plants m−2 to determine how the soil detachment rate responds to soil properties and plant root traits. In total, 24 steel tanks were planted, and two plots were used as bare soil controls. Their soil detachment rates were tested under a constant overland flow (1.5 l s−1) on a 26.2 % slope. The results showed that the soil detachment rate under the six planted densities ranged from 0.034 kg m2 s−1 to 0.112 kg m2 s−1 for BI and was ranged from 0.053 m2 s−1 to 0.132 m2 s−1 for AG, which all greatly reduced soil detachment rate and were 68.17 % to 92.33 % and 69.20 % to 87.27 % less than that of the control. In general, BI was more effective in reducing the soil detachment rate than AG, achieving a mean soil detachment rate that was 23.75 % lower. With increasing plant density, the soil detachment rate decreased as a power function (R2 = 0.23, p < 0.01). The overland flow hydraulic characteristics, soil properties and root traits influenced by plant density were positively or negatively correlated with the soil detachment rate. Specifically, the soil detachment rate decreased with velocity, bulk density, root length density, and increased with shear stress and the Darcy–Weisbach friction factor as power or exponential functions (R2 ranged from 0.16 to 0.54, p < 0.01). On this basis, the soil detachment rate (Dr) can be satisfactorily estimated by the overland flow velocity (v), soil bulk density (BD) and root length density (RLD) as a power function (Dr = 5.636v0.118 × BD−19.917 × RLD−0.170; R2 = 0.58; NSE = 0.78; p < 0.01).
Using high-resolution global climate models from the PRIMAVERA project to create a European winter windstorm event set
Authors: Lockwood Julia F. , Guentchev Galina S. , Alabaster Alexander , Brown Simon J. , Palin Erika J. , Roberts Malcolm J. , Thornton Hazel E.
Published: January 2022

Abstract. PRIMAVERA was a European Union Horizon 2020 project whose primary aim was to generate advanced and well-evaluated high-resolution global climate model datasets, for the beneﬁt of governments, business and society in general. Following consultation with members of the insurance industry, we have used a PRIMAVERA multi-model ensemble to generate a European winter windstorm event set for use in insurance risk analysis, containing approximately 1300 years of windstorm data. To create the storm footprints for the event set, the storms in the PRIMAVERA models are identified through tracking. A method is developed to separate the winds from storms occurring in the domain at the same time. The wind footprints are bias corrected and converted to 3-s gusts onto a uniform grid using quantile mapping. The distribution of the number of model storms per season as a function of estimated loss is consistent with re-analysis, as are the total losses per season, and the additional event set data greatly reduces uncertainty on return period magnitudes. The event set also reproduces the temporally clustered nature of European windstorms. Since the event set is generated from global climate models, it can help to quantify the non-linear relationship between large-scale climate indices such as the North Atlantic Oscillation (NAO) and windstorm damage. Although we find only a moderate positive correlation between extended winter NAO and storm damage in northern European countries (consistent with re-analysis), there is a large change in risk of extreme seasons between negative and positive NAO states. The intensities of the most severe storms in the event set are, however, sensitive to the gust conversion/bias correction method used, so care should be taken when interpreting the expected damages for very long return periods.
Using Mentor Texts to Develop Disciplinary Literacy of Scholarly Practitioners Through Dissertations in Practice
Authors: Markos Amy , Buss Ray R.
Published: January 2022

In this essay, we described how we use mentor texts (MTs) to foster students’ disciplinary literacy—reading, writing, thinking, and performing abilities in an area related to their problem of practice. We did this by carefully creating scaffolded learning experiences affording them with multiple, situated learning opportunities over time that allow students to move to central roles as scholarly practitioners where they now contribute in meaningful ways to disciplinary-based literacy. In this process, students were transformed from being readers of MTs where they were consuming the MTs for content to being producers, writers, of MTs that influenced others. This transformation was couched in Wenger’s Community of Practice framework. We provided a detailed presentation of how we implement the MT process throughout the EdD program. We discussed challenges and next steps and concluded with questions readers might consider as they contemplate whether using MTs might be beneficial to students in their programs.
Australian Cultural and Creative Activity: A Population and Hotspot Analysis: Ballarat
Authors: Kerrigan Susan , McIntyre Phillip , McCutcheon Marion
Published: January 2022

Description Ballarat sits on Wathaurong land and is located at the crossroads of four main Victorian highways. A number of State agencies are located here to support and build entrepreneurial activity in the region. The Ballarat Technology Park, located some way out of the heart of the city at the Mount Helen campus of Federation University, is an attempt to expand and diversify the technology and innovation sector in the region. This university also has a high profile presence in the city occupying part of a historically endowed precinct in the city centre. Because of the wise preservation and maintenance of its heritage listed buildings by the local council, Ballarat has been used as the location for a significant set of feature films, documentaries and television series bringing work to local crews and suppliers. With numerous festivals playing to the cities strengths many creative embeddeds and performing artists take advantage of employment in facilities such as the Museum of Australian Democracy at Eureka. The city has its share of start-ups, as well as advertising, design and architectural firms. The city is noted for its museums, its many theatres and art galleries. All major national networks service the TV and radio sector here while community radio is strong and growing.
Australian Cultural and Creative Activity: A Population and Hotspot Analysis: Albany and Denmark
Authors: Ryan Mark David , Hearn Greg , McCutcheon Marion , Cunningham Stuart , Kirkwood Katherine
Published: January 2022

Located a 45-minute drive apart from each other in WA’s Great Southern Region, Albany and Denmark attract creative practitioners who are drawn to the region’s natural beauty and country lifestyle. A regional services hub, Albany has a robust creative services presence with a legacy media sector that functions as a hub for public and commercial media organisations servicing Great Southern and the Wheatbelt. Denmark, while a much smaller town, is renowned nationally as an enclave for locally, nationally, and internationally acclaimed artists and creatives.
A new student-led dissection approach to the glenohumeral joint
Authors: Leigh Robert J. , Merrick Deborah
Published: January 2022

Modern day anatomy educators face many educational challenges associated with changes in curriculum, institutional reorganization and reduced teaching hours—all alongside criticism that medical students’ anatomical knowledge at graduation is insufficient. At the University of Nottingham in the United Kingdom, a traditional approach to full body cadaveric dissection is carried out in the undergraduate medical curriculum, using dissection manuals based on long- published dissector guides. First-year medical students dissect the shoulder region in a superficial manner allowing good visualization of musculature and surrounding neurovascular structures, although observation of the internal joint is significantly limited. This study reports a student-led adaption to a novel dissection approach of the glenohumeral joint, which involves splitting the humeral head to expose the internal joint capsule in exceptional detail. The prosection generated was incorporated into an on-line teaching package for first-year medical students. Students’ knowledge of the region was assessed before and after accessing the on-line teaching material, and results highlighted a significant improvement in anatomical knowledge after completion of the package (P = 0.013). First-year medical students who view the novel dissection also out-performed second-year medical students who had experienced traditional teaching of this region (P = 0.002). This study has demonstrated that a novel dissection of the glenohumeral joint can provide educational benefit by increasing anatomical knowledge of the region. Furthermore, student-led innovations may act as a powerful means of achieving much- needed reform in the field of musculoskeletal anatomy education.
Impact of a multimodal anatomy CPD course on intravenous cannulation skills – An Irish radiographers and radiation therapists’ perspective
Authors: Lone Mutahira , Sheikh Ahmad H. , Factor Andreea , Moore Niamh , Javaid Muhammad A.
Published: January 2022

Radiographers and radiation therapists continually upgrade their knowledge to remain informed and competent in modern radiological imaging techniques. Despite the generally agreed upon significance of anatomy for successful interpretation of imaging modalities, its link with clinical performance of radiographers and radiation therapists has not been highlighted before. The above-stated gap in the literature was addressed by employing an anatomy-based CPD course and investigating its influence on intravenous cannulation and administration skills of 10 radiographers and 4 radiation therapists. The course comprised interactive anatomy tutorials (employing vascular histology e-modules and vascular prosections), lectures and simulation sessions to practice IV cannulation. Likert questionnaires were employed to gauge attitudes and interests, prior to and after the course. At the end of the course, participants perceived anatomy prosections/dissection more useful compared to other learning modalities, including social media, textbooks, e-learning, plastic models and lectures. This corresponded with a significant increase in their perceived level of anatomy knowledge and confidence in identifying structures on prosections, and tracing vessels on radiographs and body surface. Anatomy-based CPD course was valued with regards to their career progression and enhancement of anatomical knowledge. Furthermore, the use of prosections and hands-on practical sessions was highly commended and a desire to attend similar future courses was expressed. Lastly, participants identified factors facilitating or hindering course attendance and offered advice to improve efficacy of future courses. We conclude that an interactive anatomy-based CPD—employing multimodal pedagogies—can be effective in enhancing anatomy knowledge and clinical competence of radiographers and radiation therapists.
An unusual case of quadruple polyorchidism in a human cadaver mimicking bilateral lipoma
Authors: Talarico Jr Ernest F. , Castaneda Joseph G. , Wahab Sana M. , Paulus Katelyn M. , Walsh Jack D. , Stromberg Amy E. , Olson Victoria N. , Janus Paul J. , Rocco Nicholas R.
Published: January 2022

Polyorchidism is a rare congenital disorder defined as the presence of more than two testicles for which the underlying etiology is unknown. This report examines a novel case, correlates findings to the literature, and discusses potential mechanisms of dysgenesis. This study was conducted on a 96-year-old male cadaver. Meticulous skilled dissection was done with careful attention to the pelvis, the inguinal region, the scrotum and testes. Measurements of the scrotal testes (STs), supernumerary testes (SNTs), scrotal epididymides (SEs), supernumerary epididymides (SNEs), ductus deferens (DD) and supernumerary ductus deferens (SDD) were taken, and testicular volume was calculated. Sagittal sectioning of STs, SNTs, SEs and SNEs was performed and, using standard histologic protocol, tissues were processed, stained with H&E, and examined. Histological findings supported the anatomical suspicion of high, bilateral inguinal polyorchdism, or tetraorchdism, in this patient. STs and SNTs have normal, gross morphological features. The left SNT was supplied by the testicular artery, and the right SNT by the inferior epigastric artery. Both SNTs and SNEs were infiltrated with adipose tissue, whereas the scrotal homologues were histologically normal. Testicular volumes were 26.5 cm3 and 23.7 cm3, and 12.3 cm3 and 0.55 cm3, for the left and right STs and SNTs, respectively. The left and right SEs measured 7.2 cm and 7.0 cm; the left and right SNEs measured 4.7 cm and 1.7 cm, respectively. The left DD measured 40.2 cm from the scrotum. The SDD from the left SNT measured 5.9 cm and joined the main ductus 16 cm proximal to its origin. The right main DD measured 39.2 cm, and the SDD from the right SNT was 3.2 cm and joined the main DD 17.4 cm proximal to its origin. The current work suggests a novel classification for polyorchidism of Type 3, Subgroup B, or SNT attached to the draining epididymis and vas deferens without reproductive potential and SNT located outside the scrotal sac. Clinicians must correlate anatomical and histological findings in suspected polyorchids to avoid misdiagnosis of SNTs as benign lipomas.
Métricas da informação sobre gestão ambiental na pecuária
Authors: Fernandes Alice Munz , Malafaia Guilherme Cunha , Teixeira Odilene de Souza , Santos Francisca Viviane dos
Published: January 2022

O objetivo desta pesquisa foi caracterizar as publicações científicas sobre gestão ambiental na atividade pecuária a partir de métricas da informação. Para isso, empregou-se uma análise cientométrica pautada em técnicas de bibliometria e sociometria. A partir de uma busca na base de dados Web of Science, considerando como período de publicações todos os anos limitados até agosto de 2019, obteve-se um portfólio composto por 105 artigos científicos. Para operacionalizar a análise dos dados e possibilitar a organização e formações de redes utilizaram-se os softwares VOSviewer e UCINET. Os resultados obtidos demonstraram que o portfólio de estudos está distribuído entre 82 journals e revistas científicas distintas. Também constatou-se que nos últimos cinco anos o interesse do pesquisadores sobre a temática também intensificou-se, respondendo por aproximadamente 42% do total das publicações. Para a análise das cocitações considerou-se como unidade analítica os autores citados que possuíam ao menos seis vínculos de cocitação, resultando em 34 autores dentre os 3.951 identificados. A vista disso, formaram-se três clusters e 59 ligações, distribuídos da seguinte forma: (i) formado por nove autores; (ii) formado por três autores, e; (iii) formado por dois autores. Portanto, verifica-se a maximização do interesse dos pesquisadores sobre o assunto ao longo dos últimos anos, bem como as extensas redes de colaboração
Espaços de comunicação e de convivência delineados com o Museu do Amanhã
Authors: Drigo Maria Ogécia , Benetti Bianca Zanoni Faião
Published: January 2022

Este artigo tem como objetivo inventariar os possíveis significados do Museu do Amanhã - obra do arquiteto Santiago Calatrava, que compõe o projeto de revitalização do centro histórico da cidade do Rio de Janeiro, no Brasil - enquanto signo, na perspectiva peirceana, o que leva a identificar espaços de comunicação e de convivência então construídos. Para tanto, vale-se de abordagem etnográfica e análise de experiências no local, aqui reavivadas com o auxílio de fotografias lá realizadas. O Museu do Amanhã constrói espaços que propiciam a contemplação, que contribuem para a reconstrução da imagem da cidade pelos usuários. O artigo é relevante por tornar evidente os espaços de comunicação e de convivência que se instauram com o Museu do Amanhã.
Relatos da vida real:
Authors: Cruz Daiane Rodrigues da , Oliveira dos Santos Marta , Barth Mauricio
Published: January 2022

Diante do universo de opções entre marcas e produtos nos dias atuais, o desafio da publicidade está em encontrar estratégias de comunicação que estabeleçam uma conexão com o consumidor, influenciando no seu poder de escolha. A partir dessa perspectiva, o presente artigo tenciona analisar o emprego do storydoing na campanha da marca Brahma “Um Brinde ao que realmente importa” por meio de análise de conteúdo, prevendo três categorias construídas, a fim de identificar nesta narrativa a relação afetiva entre marca e consumidor, pela participação deste na história da marca. A pesquisa realizada identifica que há um discurso emocional na construção de reposicionamento de marca da Brahma, potencializado pela estratégia do storydoing.
Inserção das lutas na educação física escolar da cidade de Muriaé-MG
Authors: Rocha Ferreira Nicoly , Loth Costa Júlia , Aparecida Hudson Tassiana , Fernandes Filgueiras Meireles Juliana
Published: January 2022

O objetivo foi verificar se os professores de Educação Física escolar utilizam o conteúdo Lutas em suas aulas na cidade de Muriaé - MG. Participaram da pesquisa sete professores de educação física de escolas públicas e privadas. Foi aplicada uma entrevista semiestruturada e os dados foram analisados através da Análise de Conteúdo. Observou-se que apenas dois professores desenvolvem o conteúdo lutas em suas aulas. Falta de preparo e conhecimento foram apontados como os principais motivos para a não abordagem desse conteúdo nas aulas. Concluiu-se que as lutas ainda são pouco utilizadas nas aulas de Educação Física escolar, e que a formação de professores é um ponto chave para a solução dessa defasagem.
ANALYSIS OF REGULATORY AND LEGAL ASPECTS OF THE DELIMITATION OF THE KAZAKH-RUSSIAN BORDER
Authors:   Chief Researcher,“Astana” International Scientific Complex, Dean ofthe Higher School of Social Sciences and Humanities ofAstana International University, Ibrayeva Aigerim , Satbayeva Aizhan ,   Kazakh National Agrarian Research University
Published: January 2022

The world community of states is built on a territorial basis. In international law, the territory of a State is recognized as one of its main features. The peculiarity of the state territory is that it is under the sovereignty of the state, the manifestation of state sovereignty is the jurisdiction of the state. Borders are of great importance for determining the limits of the territory, ensuring the security of the state. On the basis of international treaties and domestic national legislation, the State establishes the legal regime of the Territory. The purpose of the article is to consider the key aspects of the legal registration of the Kazakh-Russian border. The article discusses the main milestones of legal support for the delimitation and demarcation of the borders of the Republic of Kazakhstan and the Russian Federation.
CONNECTIVITY OF CHINESE RAILWAYS IN CENTRAL ASIA AND ITS FUTURE
Authors:   PhD student of Wuhan University, Wuhan, China / Kazakh Ablai khanUniversity of IR&WL (Almaty, Kazakhstan), Yermekbayev Adilbek , Uralbayev Samat ,   Kazakh Ablai khan University of IR&WL
Published: January 2022

The article explores the current state and future scenario of the Chinese railway lines routes through Central Asia and Afghanistan taking into account the Taliban regime. Since ancient times, Central Asia has been a crossroad of trade routes, which in modern times largest geopolitical actors are trying to revive. The concept of the Silk Road, which a few decades ago lived only on the pages of history textbooks, firmly settled on the front pages of newspapers, in analytical reports and development strategies of the states of Central Asia. However, times have changed, and the countries of Central Asia are trying to work hard to get access to the seas. And the railways are of paramount importance in this process. Trading via railways is vital for landlocked Central Asian states and in its turn, the competition is high among them to negotiate with Beijing to invest in the project. Furthermore, China and Uzbekistan have a chance to deal with the railway extension to Pakistan and Iran through Afghanistan by negotiating with the Taliban administration.
قضايا دعوية طبية
Authors: عبد الرحمن إبراهيم محمد الفكي
Published: January 2022

قضايا دعوية طبية

This research, in its two sections, is a legislative originalization and an explanation to the constant Islam stand from the modern medical Issues as : Euthansia, alternative mother, cloning and test-tubes babies.

Islam rejects these modernized things and devilish ways because they degenerate the human dignity which is secured and originalized by Islamic Sharia’.

These conducts don’t conform with the methods legislated by All?h for begetting in all the stages of preliminary creation.
È o non è blu? La metaemoglobinemia
Authors: Allegorico Annalisa , Umano Giuseppina , Apicella Andrea , Rosa Margherita
Published: January 2022

A case of methemoglobinemia in a 7-month infant due to the ingestion of improperly stored spinach is presented. The diagnostic and therapeutic implications are discussed.
Musikk-estetiske væremåter hos førskolebarn
Authors: Lie Jorunn B.
Published: January 2022

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Kunstformidling for barn og unge – utenfra, ovenfra, innenfra?
Authors: Aure Venke
Published: January 2022

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Skolen og estetikken – problemer og dilemmaer i grunnskolens kunst- og kulturformidling.
Authors: Bringager Frithjof
Published: January 2022

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La oss gjøre det sammen: Foreldresamarbeid i praksis – et utviklingsprosjekt i barnehagen
Authors: Fætten Wigdis
Published: January 2022

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Accelerated orphan drug approval: surrogate endpoints
Authors: Candida Fratazzi  , Jixiao Niu
Published: January 2022

Today, orphan drug development is confronted with significant challenges represented by the considerable complexity, diversity of clinical manifestations, and competition in study recruitment. Thus, surrogate endpoints adoption plays a crucial role in rare disease trials by minimizing costs, the number of subjects, and study duration. Surrogate endpoints, to substitute for a direct measure of how patients feel, function, or survive, must be biomarkers that directly correlate with disease clinical manifestations and predict the impact of study drug on the long-term disease progression. Validation of surrogate endpoints for accuracy and sensitivity is essential to maximize its benefit and utility. These validation criteria include reliability, reproducibility, keenness, and a direct reflection of patient feeling, function, or survival upon treatment. On the other hand, the selection of surrogate endpoints may be pretty complex, and making mistakes may lead to inaccurate estimates of the clinical benefit. Finally, surrogate endpoints contribute to a composite endpoint when studying drug benefits patients in multiple ways, and not all the measured components are detected in each patient. Furthermore, a composite endpoint comprised of multiple surrogate endpoints could improve statistical efficiency. Selection and qualification of biomarkers for surrogate endpoints and accelerated market approval is often a complex process that requires experience and method. Today, we contributed to developing orphan drugs for many rare diseases, including Neurological Diseases, Lysosomal Storage Diseases, Metabolic Conditions, Immune Disorders, and Cancers. In conclusion, surrogate endpoints play an essential role in orphan drug development, benefiting patients and the healthcare system.
EL DETONANTE EVOLUTIVO DE LA NARCOLITERATURA COLOMBIANA EN EL RUIDO DE LAS COSAS AL CAER DE JUAN GABRIEL VÁZQUEZ: ENTRE MEMORIA, CAMBIO Y PARODIA
Authors: Santos Danilos , Urgüelles Latorre Ingrid
Published: January 2022

La memoria sirve para leer las novelas sicarescas desde La Virgen de los sicarios (1994) hasta textos recientes como El ruido de las cosas al caer (2011) de Juan Gabriel Vásquez. Esta última se estructura desde esa base y se constituye en la escritura generacional del trauma post Pablo Escobar. El presente trabajo revisa esta novela en consonancia con la evolución literaria y la mutación del género de la narcoliteratura colombiana en el siglo XXI. La memoria indica dicha mutación, no solo como memoria del trauma nacional, sino como memoria interna del subgénero. Así, este artículo interpreta el texto de Vásquez y propone una oscilación entre una ficción de la memoria traumática nacional a un nuevo relato narcoliterario, paródico y afín a la sicaresca antioqueña retraducida en el siglo XXI.
LA INDIVIDUALIDAD DETRAÍDA. INDISPOSICIONES DE LA RELACIÓN EN WERNER HAMACHER
Authors: Durán Rojas Cristóbal
Published: January 2022

En el presente artículo intentaremos proporcionar una respuesta tentativa para dar cuenta de un rasgo o trazo temático que a nuestro parecer se muestra insistente en la escritura de Werner Hamacher. Dicha insistencia se hace patente cuando se trata de hacer comprensible la naturaleza de la relación, naturaleza que no ha sido abordada debidamente en la historia del pensamiento (por ejemplo, con Aristóteles o Hegel, entre otros). Sea ella entendida como una diferencia previa a la diferencia ontológica, como una relación indiscernible entre lenguas en la traducción, o como dirección intensiva del lenguaje hacia aquello que no puede referir, la relación siempre se muestra como indisponible, es decir, como aquello que no puede ser determinado o definido como una parte de un todo o como un término individuado. Intentaremos mostrar que una clave de lectura que permite entender la singularidad de esta relación es la comprensión de la individualidad que desarrolla Hamacher y que consideramos indisociable de un pensamiento de la relación como el que propone.
BLOQUEIO NERVOSO PERIFÉRICO COMO TRATAMENTO CIRÚRGICO PARA DOR DE CABEÇA DE USO EXCESSIVO DE MEDICAMENTOS: DOIS RELATÓRIOS DE CASO
Authors: Ferreira Fonseca Weiler , Teixeira Borges Neves Filipe , José da Silva Ledismar
Published: January 2022

Dor de cabeça de uso excessivo de drogas (EMC) é uma dor de cabeça secundária que ocorre por 15 ou mais dias por mês em pacientes com diagnóstico pré-existente de dor de cabeça primária, o que leva ao consumo excessivo regular de medicamentos sintomáticos de dor de cabeça por 10 dias em casos de ergotamina, tripulações, opioides e combinações de analgésicos, ou por mais de 15 dias em casos de analgesics não opioides, ou por mais de 15 dias em casos de analgesics não opioides, ou por mais de 15 dias em casos de analgesics não opioides, ou por mais de 15 dias em casos de analgesics não opioides, ou por mais de 15 dias em casos de analgesics não opioides, ou por mais de 15 dias em casos de analgesics não opioides, ou por mais de 15 dias em casos de analgesics não opioides, ou por mais de 15 dias em casos de analgesics não opioides, ou por mais de 15 dias em casos de angesics não opioides, paracetamol e anti-inflamatórios não esteroides por mês por mais de 3 meses. O CEM é uma das doenças incapacitantes que teve a maior incidência desde a década de 1990. A principal medida terapêutica é a retirada do medicamento superusuado. No entanto, alguns pacientes não respondem totalmente ao protocolo de retirada e, além disso, aqueles que apresentaram melhora, ainda têm dores de cabeça mensais, embora suficientes para não serem diagnosticados com EMF. Os blocos anestésicos são um recurso para o gerenciamento de diferentes dores de cabeça, seja como tratamento isolado ou combinado, ou para o tratamento da dor de cabeça de recuperação após a retirada de medicamentos. Os anestésicos locais são capazes de interromper reversivamente a condução do impulso nervoso bloqueando canais de sódio dependentes de tensão através de sua fração não ionizada, reduzindo assim a excitabilidade celular. Assim, este estudo teve como objetivo relatar o uso do bloqueio nervoso periférico como um tratamento alternativo e eficaz para o MOH.
Preocupações caritativas das rainhas medievais portuguesas
Authors: Drumond Braga Paulo
Published: January 2022

This article aims to study several aspects of the charitable action of the first Portuguese consort queens (12th-15th centuries).
A assistência aos expostos de Lisboa: a aprendizagem de ofícios da construção (1777-1812)
Authors: Alves Milene
Published: January 2022

Among other strategies that the Real Casa dos Expostos, managed by Misericórdia of Lisbon, has adopted in an attempt to ensure the autonomy of the young people it has assisted, it has promoted training in various crafts through contracts with masters of differents trades, in which it has determined the obligations that they had to fulfil towards the institution and apprentices. The fundamental objective was to prepare them to work as journeymen, as stated by the tripartite hierarchy of crafts. Amongst contracts of apprenticeship signed between 1777 and 1812, I will highlight those relating to the building area. The aim is to characterize one of the strategies promoted by that institution to insert the young people it assisted, at a time in their lives when it was not constrained to maintain its assistance.
Romper géneros
Authors: Serrano Pedro
Published: January 2022

This essay argues that the paths of translation intersect and form different configurations as one advances in it and in the study of it. It also proposes that translated literature belongs to the literary history of the language in which it appears and, therefore, should be part of the studies in that language and those literatures. It begins by comparing different translations of Horace’s Ars poetica, goes through the argumentation in philosophy of science about the preeminence of practice over theory, and states that translating poetry is writing poetry. It concludes by proposing that literary translation is a craft involving creation, criticism, and theory.