bluuebunny/crossref_metadata_2025 huggingface dataset:
When Land Becomes a Burden: An Analysis of an Underperforming Zambian Land Deal
Authors: Salverda Tijo , Nkonde Chewe
Published: October 2021

From 2011 onward, a European agribusiness progressively purchased about 38,000 hectares of land in Zambia. Although operations have commenced on the ground, only part of the land has been developed. Salverda and Nkonde look at the reasons for and implications of this partial development, focusing particularly on how, in such a context, Zambia’s slow-moving land administration, lack of financing, and the presence of rural residents on the purchased land have become self-reinforcing challenges. Their aim is to provide insights about why (very large) land deals often fail to achieve their projected capacity, leaving both investors and local residents in limbo.
Against Paretianism: A Wealth Creation Approach to Business Ethics
Authors: Young Carson
Published: October 2021

How should we distinguish between ethical and unethical ways of pursuing profit in a market? The market failures approach (MFA) to business ethics purports to provide an answer to this question. I argue that it fails to do so. The source of this failure is the MFA’s reliance on Pareto efficiency as a core ethical principle. Many ethically “preferred” tactics for seeking profit cannot be justified by appeal to Pareto efficiency. One important reason for this is that Pareto efficiency, as understood by the theory of welfare economics upon which the MFA relies, assumes a static conception of efficiency. This is a problem because many ethically “preferred” tactics can only be justified by appeal to dynamic efficiency considerations. I argue that, instead of Pareto efficiency, we should look to the value of wealth creation to understand the ethical constraints on how market actors may pursue profit.
On the lifespan of recirculating suspensions with pulsatile flow
Authors: Jeronimo Mark D. , Rival David E.
Published: October 2021

A Lagrangian analysis is performed to measure the rate at which recirculating fluid is replaced (depleted) in pulsatile flows. Based on this approach, we then investigate how depletion is affected in dense suspensions. Experiments are conducted for pure liquid as well as suspensions with volume fractions of

$\varPhi =5\,\%$

, 10 % and 20 %. Using Lagrangian tracking and pathline extension techniques, the depletion of the recirculation region is quantified via the trajectories of individual fluid parcels exiting the domain. Pulsatile flows with varying concentrations of hydrogel beads, up to a volume fraction of 20 %, are compared at mean Reynolds numbers of

$Re=4800$

, 9600 and 14 400, while the Strouhal number (

$St=0.04$

, 0.08 and 0.15) and amplitude ratio (

$\lambda =0.25$

, 0.50 and 0.95) are systematically varied. A so-called ‘depletion efficiency’ is calculated for each test case, which is shown to increase with increasing Strouhal number and amplitude ratio. For most pulsatile cases, periodic vortex formation significantly increases depletion efficiency through enhanced entrainment of recirculating fluid. Conversely, low-amplitude pulsatile flows are dominated by Kelvin–Helmholtz instabilities, which do not penetrate into the recirculation region, and thus their depletion efficiency is markedly lower as a result. The efficiency trends and depletion mechanisms remain virtually unchanged between the pure liquid and each of the suspension concentrations under almost all flow conditions, which forms an unexpected conclusion. The only exception is for low-amplitude and steady flows, where increasing the suspension volume fraction is shown to suppress fluid transport across the shear layer, which in turn slows depletion and decreases the overall depletion efficiency.
Bifurcation scenario for a two-dimensional static airfoil exhibiting trailing edge stall
Authors: Busquet Denis , Marquet Olivier , Richez François , Juniper Matthew , Sipp Denis
Published: October 2021

We numerically investigate stalling flow around a static airfoil at high Reynolds numbers using the Reynolds-averaged Navier–Stokes equations (RANS) closed with the Spalart–Allmaras turbulence model. An arclength continuation method allows to identify three branches of steady solutions, which form a characteristic inverted S-shaped curve as the angle of attack is varied. Global stability analyses of these steady solutions reveal the existence of two unstable modes: a low-frequency mode, which is unstable for angles of attack in the stall region, and a high-frequency vortex shedding mode, which is unstable at larger angles of attack. The low-frequency stall mode bifurcates several times along the three steady solutions: there are two Hopf bifurcations, two solutions with a two-fold degenerate eigenvalue and two saddle-node bifurcations. This low-frequency mode induces a cyclic flow separation and reattachment along the airfoil. Unsteady simulations of the RANS equations confirm the existence of large-amplitude low-frequency periodic solutions that oscillate around the three steady solutions in phase space. An analysis of the periodic solutions in the phase space shows that, when decreasing the angle of attack, the low-frequency periodic solution collides with the unstable steady middle-branch solution and thus disappears via a homoclinic bifurcation of periodic orbits. Finally, a one-equation nonlinear stall model is introduced to reveal that the disappearance of the limit cycle, when increasing the angle of attack, is due to a saddle-node bifurcation of periodic orbits.
Influence of molecular transport on burning rate and conditioned species concentrations in highly turbulent premixed flames
Authors: Lee H.C. , Dai P. , Wan M. , Lipatnikov A.N.
Published: October 2021

Apparent inconsistency between (i) experimental and direct numerical simulation (DNS) data that show the significant influence of differential diffusion on the turbulent burning rate and (ii) recent complex-chemistry DNS data that indicate mitigation of the influence of differential diffusion on conditioned profiles of various local flame characteristics at high Karlovitz numbers, is explored by analysing new DNS data obtained from lean hydrogen–air turbulent flames. Both aforementioned effects are observed by analysing the same DNS data provided that the conditioned profiles are sampled from the entire computational domain. On the contrary, the conditioned profiles sampled at the leading edge of the mean flame brush do not indicate the mitigation, but are significantly affected by differential diffusion phenomena, e.g. because reaction zones are highly curved at the leading edge. This observation is consistent with a significant increase in the computed turbulent burning velocity with decreasing Lewis number, with all the results considered jointly being consonant with the leading point concept of premixed turbulent combustion. The concept is further supported by comparing DNS data obtained by allowing for preferential diffusion solely for a single species, either atomic or molecular hydrogen.
Statistical characteristics of turbulent mixing in spherical and cylindrical converging Richtmyer–Meshkov instabilities
Authors: Li Xinliang , Fu Yaowei , Yu Changping , Li Li
Published: October 2021

In this paper, the Richtmyer–Meshkov instabilities in spherical and cylindrical converging geometries with a Mach number of approximately 1.5 are investigated by using the high resolution implicit large eddy simulation method, and the influence of the geometric effect on the turbulent mixing is investigated. The heavy fluid is sulphur hexafluoride (SF6), and the light fluid is nitrogen (N2). The shock wave converges from the heavy fluid into the light fluid. The Atwood number is 0.678. The total structured and uniform Cartesian grid node number in the main computational domain is 20483. In addition, to avoid the influence of boundary reflection, a sufficiently long sponge layer with 50 non-uniform coarse grids is added for each non-periodic boundary. Present numerical simulations have high and nonlinear initial perturbation levels, which rapidly lead to turbulent mixing in the mixing layers. Firstly, some physical-variable mean profiles, including mass fraction, Taylor Reynolds number, turbulent kinetic energy, enstrophy and helicity, are provided. Second, the mixing characteristics in the spherical and cylindrical turbulent mixing layers are investigated, such as molecular mixing fraction, efficiency Atwood number, turbulent mass-flux velocity and density self-correlation. Then, Reynolds stress and anisotropy are also investigated. Finally, the radial velocity, velocity divergence and enstrophy in the spherical and cylindrical turbulent mixing layers are studied using the method of conditional statistical analysis. Present numerical results show that the geometric effect has a great influence on the converging Richtmyer–Meshkov instability mixing layers.
Positive youth development: A brief review of literature with implications for school-based psychological interventions
Authors: Buenconsejo Jet U. , Datu Jesus Alfonso D.
Published: October 2021

There is a recognition about the mental health, educational, and career-related benefits of positive youth development (PYD) in children and youth. This brief review provides an overview of the current application of PYD in school settings. We begin by summarising the common conceptualisations of PYD along with similar and distinct features in such models. Then, we discuss the current status of PYD research and highlight the academic and psychological payoffs of PYD-oriented programs in schools. Importantly, this review elaborates future directions and practical implications for PYD researchers and practitioners in school contexts.
Exploring barriers to social inclusion for disabled people: perspectives from the performing arts
Authors: Collins Ayse , Rentschler Ruth , Williams Karen , Azmat Fara
Published: October 2021

Although the potential of arts to promote social inclusion is recognised, barriers to social inclusion for disabled people in the arts is under-researched. Based on 34 semi-structured interviews with disabled people and those without disability from four arts organisations in Australia, the paper identifies barriers for social inclusion for disabled people within performing arts across four dimensions: access; participation; representation and empowerment. Findings highlight barriers are societal, being created with little awareness of needs of disabled people, supporting the social model of disability. Findings have implications beyond social inclusion of disabled people within the arts, demonstrating how the arts can empower disabled people and enable them to access, participate and represent themselves and have a voice. Our framework conceptualises these four barriers for social inclusion for disabled people for management to change.
Influence of wild, local and cultivated tobacco varieties on the oviposition preference and offspring performance ofSpodoptera litura
Authors: Li Xiaohong , Huang Zhiyou , Yang Xianjun , Wu Shaolong
Published: October 2021

The influences of different plants on herbivores have recently attracted research interest; however, little is known regarding the effects of wild, local and cultivated varieties of the same plant from the same origin on herbivores. This study aimed to examine the effects of different tobacco varieties from the same origin on the oviposition preference and offspring performance ofSpodoptera litura. We selected two wild (‘Bishan wild tobacco’ and ‘Badan wild tobacco’), two local (‘Liangqiao sun-cured tobacco’ and ‘Shuangguan sun-cured tobacco’) and two cultivated (‘Xiangyan No. 5’ and ‘Cunsanpi’) tobacco varieties from Hunan Province, China. We found that femaleS. lituravaried in oviposition preferences across the tobacco varieties. They preferred to lay eggs on the cultivated varieties, followed by the local varieties, with the wild varieties being the least preferred. Furthermore, different tobacco varieties significantly influenced the life history parameters ofS. litura. Survival rate, pupal weight, emergence rate and adult dry weight decreased in the following order: cultivated varieties > local varieties > wild varieties. Conversely, the pupal stage and development period decreased in the following order: wild varieties > local varieties > cultivated varieties. Therefore, we conclude that wild tobacco varieties have higher resistance toS. liturathan cultivated and local varieties, reflecting the evolutionary advantages of wild tobacco varieties.
The burden of hypertension and unmet need for hypertension care among men aged 15–54 years: a population-based cross-sectional study in India
Authors: Kothavale Ajinkya , Puri Parul , Yadav Suryakant
Published: October 2021

Hypertension is one of the primary causes of morbidity and premature mortality among the working-age population in India. This study evaluated the burden of hypertension and unmet need for hypertension care among working-age men aged 15–54 years in India using data from the fourth round of the National Family Health Survey (NFHS-4, 2015–16). An individual was recognized as hypertensive if his blood pressure was over 140/90 mmHg or if he was consuming anti-hypertensive medication to lower his blood pressue. The study design was based on the Rule of Halves framework. Hypertensive cases were segmented into five analytical levels: (1) total, (2) screened, (3) diagnosed, (4) treated and (5) controlled cases. The prevalence of hypertension was 16% (n=16,254) among the men aged 15–54 years. Of the total hypertensive individuals, 63.2% (10,314) were screened, 21.5% (3428) were diagnosed, 12.6% (1862) were treated and only 6.1% (905) had controlled blood pressure. Of the screened individuals, 66.8% (6886) had never been diagnosed, 45.7% (1566) of those diagnosed had not receive treatment and 51.4% (957) of those treated still had uncontrolled blood pressure. The analyses revealed that 36.5% (5940) of hypertensive individuals were lost at the screening stage. The results demonstrate that there is a significant burden of hypertension and unmet need for hypertension care among men aged 15–54 in India. There is an urgent need to develop suitable strategies and programmes to manage this rising burden of hypertension among men, and reduce losses in the hypertension care continuum.
Parkinson's disease: the nutrition perspective
Authors: Ó Breasail Mícheál , Smith Matthew D. , Tenison Emma , Henderson Emily J. , Lithander Fiona E.
Published: October 2021

Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's disease and affects about 1% of the population over the age of 60 years in industrialised countries. The aim of this review is to examine nutrition in PD across three domains: dietary intake and the development of PD; whole body metabolism in PD and the effects of PD symptoms and treatment on nutritional status. In most cases, PD is believed to be caused by a combination of genetic and environmental factors and although there has been much research in the area, evidence suggests that poor dietary intake is not a risk factor for the development of PD. The evidence about body weight changes in both the prodromal and symptomatic phases of PD is inconclusive and is confounded by many factors. Malnutrition in PD has been documented as has sarcopaenia, although the prevalence of the latter remains uncertain due to a lack of consensus in the definition of sarcopaenia. PD symptoms, including those which are gastrointestinal and non-gastrointestinal, are known to adversely affect nutritional status. Similarly, PD treatments can cause nausea, vomiting and constipation, all of which can adversely affect nutritional status. Given that the prevalence of PD will increase as the population ages, it is important to understand the interplay between PD, comorbidities and nutritional status. Further research may contribute to the development of interventional strategies to improve symptoms, augment care and importantly, enhance the quality of life for patients living with this complex neurodegenerative disease.
Dietary health in the context of poverty and uncertainty around the social determinants of health
Authors: Thompson Claire
Published: October 2021

Lower household income has been consistently associated with poorer diet quality and poorer dietary health outcomes. Households experiencing poverty find themselves unable to afford enough food, and the food that they can afford is often poor quality, energy dense and low in nutrients. However, the relationship between diet, poverty and health is complex. Not everyone on a low income has a poor diet. Poverty is about more than low incomes and it is not a uniform experience. Particular aspects of the experience of poverty have implications for diet and dietary health. It is increasingly apparent thatuncertaintyis one of those aspects. Recession, welfare policy, employment trends and widening inequality have created more uncertainty for those on low incomes. In the context of heightened uncertainty, all aspects of household food provisioning – including budgeting, shopping, storage, meal planning and cooking – are more difficult and sometimes impossible. This review will draw on research about food practices and dietary health in low-income neighbourhoods to explore the ways in which experiences of prolonged uncertainty shape dietary practices and impact health and well-being.
Parasitic nematodes of the genus Syphacia Seurat, 1916 infecting Cricetidae in the British Isles: the enigmatic status of Syphacia nigeriana
Authors: Behnke Jerzy M. , Stewart Alex , Smales Lesley , Cooper Gemma , Lowe Ann , Kinsella John M. , Bajer Anna , Dwużnik-Szarek Dorota , Herman Jeremy , Fenn Jonathan , Catalano Stefano , Diagne Christophe A. , Webster Joanne P.
Published: October 2021

Oxyurid nematodes (Syphacia spp.) from bank (Myodes glareolus) and field/common (Microtus spp.) voles, from disparate geographical sites in the British Isles, were examined morphologically and genetically. The genetic signatures of 118 new isolates are provided, based primarily on the rDNA internal transcribed spacers (ITS1-5.8S-ITS2) region and for representative isolates also on the small subunit 18S rDNA region and cytochrome c oxidase subunit 1 (cox-1) gene locus. Genetic data on worms recovered from Microtus spp. from the European mainland and from other rodent genera from the Palaearctic, North America and West Africa are also included. We test historical hypotheses indicating that S. nigeriana is a generalist species, infecting a range of different rodent genera. Our results establish that S. nigeriana is a parasite of both bank and field voles in the British Isles. An identical genotype was also recorded from Hubert's multimammate mouse (Mastomys huberti) from Senegal, but Mastomys spp. from West Africa were additionally parasitized by a related, although genetically distinct Syphacia species. We found no evidence for S. petrusewiczi in voles from the British Isles but isolates from Russia and North America were genetically distinct and formed their own separate deep branch in maximum likelihood molecular phylogenetic trees.
Do secondary hemiepiphytes exist?
Authors: Zotz Gerhard , Almeda Frank , Arias Salvador , Hammel Barry , Pansarin Emerson
Published: October 2021

For decades, tropical ecologists distinguished primary (PH) and secondary hemiepiphytes (SH) as two structurally dependent life forms with an epiphytic phase at, respectively, the beginning or the end of their ontogeny. However, the use of these terms has been criticized repeatedly because the term “hemiepiphyte” suggests an unsubstantiated biological similarity in ontogeny, and worse, because it is often used without a qualifier, which makes unambiguous interpretation of the life history of such species impossible. In this paper, we go one step further and ask the question whether an ontogenetic trajectory as described by the term “secondary hemiepiphyte” does exist at all. We show that until now all evidence available for the three families that were traditionally listed as taxa with SHs (Araceae, Cyclanthaceae, Marcgraviaceae) falsifies such claims, but critically discuss reports of possible SHs in other families. In all these cases unambiguous conclusions about the existence of any SH are difficult, but our detailed discussion of potential candidates is meant to provide the basis for focused field studies. Irrespective of the outcome of these studies, we urge researchers to abandon the use of the term SH for the time being: Terminological issues can be discussed once there are data.
Are recommended dietary patterns equitable?
Authors: Wang Vivian Hsing-Chun , Foster Victoria , Yi Stella S
Published: October 2021

Objective:

Dietary recommendations (DR) in the USA may be inadequate at improving diets in racial/ethnic minority communities and may require redesign of the systems driving their development over the long term. Meanwhile, cultural adaptation of evidence-based DR may be an important strategy for mitigating nutrition disparities, but less is known about the adaptability of these recommendations to meet the needs of diverse groups. We examined the content and origin of major DRs – aspects that provide context on their potential universality across populations and evaluated their potential for cultural adaptation.

Design:

Case studies of Dietary Approaches to Stop Hypertension (DASH), the Mediterranean diet (MD), the EAT-Lancet diet (EAT) and the NOVA classification system.

Setting:

United States.

Participants:

Racial/ethnic minority populations.

Results:

Current DR differ in their origin/evolution but are similar in their reductionist emphasis on physical health. DASH has been successfully adapted for some cultures but may be challenged by the need for intensive resources; MD may be more beneficial if applied as part of a broader set of food procurement/preparation practices than as just diet alone; EAT-Lancet adaptation may not honor existing country-specific practices that are already beneficial to human and environmental health (e.g. traditional/plant-based diets); evidence for cultural adaptation is limited with NOVA, but classification of levels of food processing has potential for widespread application.

Conclusions:

For DR to equitably support diverse populations, they must move beyond a Eurocentric or ‘general population’ framing, be more inclusive of cultural differences and honour social practices to improve diet and reduce disparities.
What explains the large disparity in child stunting in the Philippines? A decomposition analysis
Authors: Ulep Valerie Gilbert T , Uy Jhanna , Casas Lyle Daryll
Published: October 2021

Objective:

About one-third of under-five Filipino children are stunted, with significant socio-economic inequality. This study aims to quantify factors that explain the large gap in stunting between poor and non-poor Filipino children.

Design:

Using the 2015 Philippine National Nutrition Survey, we conducted a linear probability model to examine the determinants of child stunting and then an Oaxaca-Blinder decomposition to explain the factors contributing to the gap in stunting between poor and non-poor children.

Setting:

Philippines.

Participants:

1881 children aged 6–23 months participated in this study.

Results:

The overall stunting prevalence was 38·5 % with a significant gap between poor and non-poor (45·0 % v. 32·0 %). Maternal height, education and maternal nutrition status account for 26 %, 18 % and 17 % of stunting inequality, respectively. These are followed by quality of prenatal care (12 %), dietary diversity (12 %) and iron supplementation in children (5 %).

Conclusions:

Maternal factors account for more than 50 % of the gap in child stunting in the Philippines. This signifies the critical role of maternal biological and socio-economic circumstances in improving the linear growth of children.
Seasonal variability of women’s dietary diversity and food supply: a cohort study in rural Burkina Faso
Authors: Lourme-Ruiz Alissia , Koffi Christophe Kouamé , Gautier Denis , Bahya-Batinda Dang , Bouquet Emmanuelle , Dury Sandrine , Martin-Prével Yves , Savy Mathilde
Published: October 2021

Objective:

To investigate the seasonal variations of women’s dietary diversity (WDD) (items consumed and food supply) and its linkages with agriculture, market and wild resources.

Design:

A cohort of 300 women was followed-up over a year to investigate WDD and food sources (production, purchase or foraging). Monthly qualitative 24 h recalls allowed computing WDD Scores from a standard 10-food groups (FG) classification (WDDS-10). Associations between farm/women’s characteristics and WDDS-10 were investigated using multivariate mixed models including interaction terms factor*months.

Setting:

Tuy province, Burkina Faso.

Participants:

300 women of reproductive age.

Results:

Both dietary diversity and food sources were seasonal. The mean WDDS-10 was relatively stable from August to January (ranging from 3·1 to 3·5 FG) when farm production predominated. The WDDS-10 gradually increased from February, concomitantly with an increase in food purchases (onions, tomatoes, mangoes) and reached its highest levels (>4 FG) from March to June, when food purchases were still relatively high and when more women consumed foraged fruits (shea plums and wild grapes). Women living on farms owning > 3 plough oxen and different animal species had significantly higher WDDS-10 than others (+0·28 and +0·35 FG, respectively). Women who practiced off-farm activities also had higher WDDS-10 than those who did not (+0·21 FG, P < 0·05). Other factors, for example, the number of foraged edible species, provided advantages in terms of dietary diversity only during certain seasons (October – January, P for interaction < 0·01).

Conclusions:

Diversifying women’s diets throughout the year requires complementary interventions aimed at diversifying production, promoting foraging and increasing income-generating activities to enable food purchasing.
Towards a Sustainable Welfare State: The Role of Universal Basic Services
Authors: Coote Anna
Published: October 2021

The idea of pooling resources and sharing risks to provide universal services according to need not ability to pay was at the heart of the post-war settlement. However, decades of market ideology and deep spending cuts have left most services starved of power and resources. Universal Basic Services (UBS) offers a principled framework for policy and practice that aims to ensure everyone has access to life’s essentials. Based on need theory it combines universality with sufficiency to provide a secure social foundation for all within planetary boundaries. Needs are met in different ways, combining collective and individual measures, as illustrated by examples of childcare, housing and food. UBS can be combined with an income guarantee to ensure no-one’s income falls below an agreed level of sufficiency. Cash and services, which represent a ‘social wage’, are best understood as two sides of the same coin, supporting rather than competing with one another.
Enough is Enough: De-colonise, Diversify and De-construct the Curriculum
Authors: Housee Shirin
Published: October 2021

This article explores the importance of anti-racism in a higher Education context. With reference to the recent discussions on de-colonising the curriculum, I reflect on the importance of the Black Lives Matter movement. I argue more vehemently than ever before – enough is enough – we have no choice but to teach against racism. This article discusses the importance of de-colonising the curriculum and Higher Education and creating learning environments that open out discussions about everyday racism. This, I argue, is core to our anti-racist practise if we intend to build a fairer and a more anti-racist world.
Intra-Crisis Lesson-Drawing in Real-Time: The Pandemic Lessons Available in the UK Media during the First Months of COVID-19
Authors: Greener Ian , Powell Martin , King-Hill Sophie
Published: October 2021

This article assesses, using a framework derived from lesson-drawing, policy transfer and crisis research, the lessons offered by the media from abroad and from the past in the UK COVID-19 pandemic. The lesson-drawing literature focuses on a series of steps and questions associated with the ‘fungibility’ of lessons, and the crisis literature, with its constituent elements of threat, uncertainty and between ‘routine’ and ‘non-routine’ or ‘less routine’ crises. The article utilises the LexisNexis Database1 in order to provide a content analysis of newspaper coverage of lessons offered, giving analysis in ‘real time’ of the source of potential lessons (e.g. past pandemics or other nations), and the type of lessons (e.g. copying or instruments). Its analysis highlights the complexity of lesson-drawing in ‘real time’ in a period of considerable uncertainty, where knowledge is contested, and is subject to change over time.
Silage corn yield is reduced by burcucumber competition and drought in New York State
Authors: Averill Kristine M. , Westbrook Anna S. , Morris Scott H. , Kubinski Emma , DiTommaso Antonio
Published: October 2021

Drought stress and weed competition are two of the most important threats to corn production in the northeastern United States. Both pressures have the potential to worsen under climate change. In a 2-yr field study in Ithaca, NY, we tested the effects of drought and burcucumber, an increasingly problematic annual vine, on silage corn. Burcucumber seedlings were transplanted into corn rows at densities of 0, 0.5, 2, and 3 plants m−2and a drought treatment was later imposed with rainout shelters constructed from steel frames and high-clarity plastic. Available soil moisture was lower in drought plots (47% ± 1% in 2018 and 52% ± 2% in 2019) than no-drought plots (69% ± 1% in 2018 and 68% ± 1% in 2019). Burcucumber planting density (P = 0.008) reduced fresh silage yield. Drought also reduced fresh silage yield (P < 0.001) with a drought-by-year interaction (P = 0.007): drought reduced fresh weight by 29% in 2018 (48,000 ± 2,000 kg ha−1to 34,000 ± 3,000 kg ha−1) and by 9% in 2019 (38,000 ± 3,000 kg ha−1to 34,000 ± 3,000 kg ha−1). Burcucumber planting density and drought did not interact. Overall, our findings indicate that drought and competition from burcucumber may have additive effects on silage corn in New York State. Regardless of water availability, active weed management is required to prevent yield losses due to burcucumber. Yield losses may be similar or greater in grain corn and might increase under climate change.
Transfer of resistance alleles from herbicide-resistant to susceptible grass weeds via pollen-mediated gene flow
Authors: Jhala Amit J. , Beckie Hugh J. , Mallory-Smith Carol , Jasieniuk Marie , Busi Roberto , Norsworthy Jason K. , Bagavathiannan Muthukumar V. , Tidemann Breanne D. , Geddes Charles M.
Published: October 2021

The objective of this paper was to review the reproductive biology, herbicide-resistant (HR) biotypes, pollen-mediated gene flow (PMGF), and potential for transfer of alleles from HR to herbicide-susceptible grass weeds including barnyardgrass, creeping bentgrass, Italian ryegrass, johnsongrass, rigid (annual) ryegrass, and wild oats. The widespread occurrence of HR grass weeds is at least partly due to PMGF, particularly in obligate outcrossing species such as rigid ryegrass. Creeping bentgrass, a wind-pollinated turfgrass species, can efficiently disseminate herbicide resistance alleles via PMGF and movement of seeds and stolons. The genusAgrostiscontains about 200 species, many of which are sexually compatible and produce naturally occurring hybrids and hybrids with species in the genusPolypogon. The self-incompatibility, extremely high outcrossing rate, and wind pollination in Italian ryegrass clearly point to PMGF as a major mechanism by which herbicide resistance alleles can spread across agricultural landscapes, resulting in abundant genetic variation within populations and low genetic differentiation among populations. Italian ryegrass can readily hybridize with perennial ryegrass and rigid ryegrass due to their similarity in chromosome numbers (2n= 14), resulting in interspecific gene exchange. Johnsongrass, barnyardgrass, and wild oats are self-pollinated species, so the potential for PMGF is relatively low and limited to short distances; however, seeds can easily shatter upon maturity before crop harvest, leading to wider dispersal. The occurrence of PMGF in reviewed grass weed species, even at a low rate, is greater than that of spontaneous mutations conferring herbicide resistance in weeds and thus can contribute to the spread of herbicide resistance alleles. This review indicates that the transfer of herbicide resistance alleles occurs under field conditions at varying levels depending on the grass weed species.
Alpha-lipoic acid supplementation affects serum lipids in a dose and duration-dependent manner in different health status
Authors: Mahmoudinezhad Mahsa , Farhangi Mahdieh Abbasalizad
Published: October 2021

Abstract: Background: Many studies have investigated the effect of alpha-lipoic acid (ALA) supplementation on lipid profile, and different results have been obtained from these studies. The current systematic review and dose-response meta-analysis was conducted to achive a strong conclusion about the effect of ALA supplementation on lipid profile including total cholesterol (TC), low- and high-density lipoprotein cholesterol (LDL, HDL) and triglycerides (TG). Methods: A systematic search was performed in PubMed, SCOPUS, ProQuest and Embase for randomized placebo-controlled human trials that examined the effect of ALA supplementation on lipid profile up to November 2020. The dose and duration of ALA supplementation for included studies were ranged between 300–1200 mg/d and 2–16 weeks respectively. Weighted mean differences (WMD) and 95% confidence intervals (CIs) were used to evaluate the effect size. Cochran’s Q and I2 tests were also used to assess between-study’s heterogeneity. In addition, subgroup analysis was performed to investigate potential sources of heterogeneity. Dose-response relationship was done using fractional polynomial modeling. Results: Among all eligible studies, 12 studies with a total number of 548 participants were selected. ALA caused a significant reduction on TC (WMD): −10.78 mg/dl, 95% CI: −20.81, −0.74, P=0.002), LDL (WMD: −10.88 mg/dl, 95% CI: −19.52, −2.24, P=0.014) and TG (WMD: −31.02 mg/dl, 95% CI: −49.63, −12.42, P<0.001). There was also a non-significant increaes in HDL concentrations. In addition, dose-response analysis showed a positive association between LDL (Pnon-linearity=0.026), TG (Pnon-linearity<0.001) and duration of intervention in a non-linear model. Conclusion: The present meta-analysis revealed the beneficial effects of ALA supplementation on TC, LDL and TG levels. Moreover, the beneficial effects of ALA supplementation on LDL and TG levels was duration-dependent.
Seasonal River Export of Nitrogen to Guanting and Baiyangdian Lakes in the Hai He Basin
Authors: Yang Jing , Strokal Maryna , Kroeze Carolien , Chen Xuanjing , Bai Zhaohai , Li Hongbo , Wu Yihong , Ma Lin
Published: October 2021

Eutrophication refers to the nutrient enrichment, leading to blooms of algae. Such blooms in lakes can happen throughout the year because of the changes in nutrient and hydrological cycles. Nutrient export to lakes from rivers is the main cause of eutrophication problems. Seasonal trends in nitrogen (N) export by rivers to lakes are still not well understood. The objective of this study is, therefore, to better understand the seasonal trends in river export of dissolved inorganic N (DIN) to lakes of the Hai He Basin. To this end, we selected Guanting and Baiyangdian as representative lakes, whose drainage areas include various cropping systems. We developed a seasonal version of the Model to Assess River Inputs of Nutrients to lAkes (MARINA‐Lakes) model for Guanting and Baiyangdian while assessing N flows from the land to the lakes. The model accounts for the seasonality in human activities (e.g., cropping systems and fertilizer practices), climate, and hydrology. The effective seasons are winter (December–February), spring (March–May), summer (June–August), and fall (September–November). The model results for the year 2012 indicate that river export of DIN was highest in winter and lowest in summer. Point sources accounted for over 50% of DIN exports to Guanting and Baiyangdian across seasons. Avoiding direct discharges of animal manure (point source) in winter is needed to reduce future lake pollution. We argue that effective lake pollution control requires accounting for seasonal N cycles. Our study can support effective nutrient management and environmental policies.
Inflation of Okmok Volcano During 2008–2020 From PS Analyses and Source Inversion With Finite Element Models
Authors: Wang Jiahui , Lu Zhong , Gregg Patricia M.
Published: October 2021

Okmok volcano, located on northeastern Umnak Island along the eastern end of the Aleutian island arc, is one of the most active volcanoes in Alaska, producing multiple eruptions in the past century. The most recent eruption, which occurred during July–August of 2008, was the most explosive since the early nineteenth century. In the years following the 2008 eruption, Global Navigation Satellite System (GNSS) and Interferometric Synthetic Aperture Radar (InSAR) observations indicate that Okmok has inflated at a variable rate of 40–195 mm/yr. In this study, we investigate the post‐eruptive deformation of Okmok (2008–2020) using InSAR and GNSS. L‐band ALOS‐2, C‐band Sentinel‐1/Envisat and X‐band TerraSAR‐X data are analyzed with Persistent Scatterer (PS) InSAR method. The deformation time series calculated from InSAR and GNSS are assimilated into finite element models using the Ensemble Kalman Filter to track the evolution of the magma system through time. The results indicate that the InSAR‐derived deformation history can be well explained by a spatially stable magmatic source located in the central caldera, at about 3 km beneath the sea level, which is also believed to be the same source that produced the 1997 and 2008 eruptions. Magma accumulation in the reservoir is about from 2008 to 2020, which is about 160% and about 60% of the total reservoir volume changes during the 1997 and the 2008 eruptions, respectively.
Variations in Summer Marine Heatwaves in the South China Sea
Authors: Yao Yulong , Wang Chunzai
Published: October 2021

Marine heatwaves (MHWs) are prolonged anomalous warm seawater events that can severely impact marine ecosystems and have never been studied previously in the South China Sea. Here, we combine satellite sea surface temperature and reanalysis products to provide a systematic analysis of variations in summer MHWs in the South China Sea and potential influencing factors. The MHW days and duration, calculated as multiyear average, are mainly concentrated near the Nansha Islands and Beibu Gulf. Additionally, we find significant increasing trends in MHW days, duration, and frequency in the South China Sea during 1982–2020. The first empirical orthogonal function mode accounts for 60% of the total variance and exhibits a general mono‐sign pattern over the entire South China Sea. Increased solar radiation and released latent heat during summer MHWs contribute to high pressure in the western North Pacific. The anticyclone induced by the anomalous intensification of the western North Pacific subtropical high and its westward extension bring easterly wind anomalies to low latitudes, weakening the summer southwest monsoon south of 12°N in the South China Sea. The midwestern South China Sea upwelling weakens or even disappears due to a negative wind stress curl, causing basin‐wide severe summer MHWs. The paper also points out that more attention should be given to inter‐ocean interactions when monitoring the risks of unprecedented MHW‐related coral bleaching and marine ranching in the South China Sea.
Dipole Mode of the Precipitation Anomaly Over the Tibetan Plateau in Mid‐Autumn Associated With Tropical Pacific‐Indian Ocean Sea Surface Temperature Anomaly: Role of Convection Over the Northern Maritime Continent
Authors: Zhang Ping , Duan Anmin
Published: October 2021

Based on observational data and numerical simulation results with the Community Atmosphere Model (CAM4), version 4 atmospheric general circulation model (AGCM), the influence of the sea surface temperature anomaly (SSTA) of the tropical Pacific–Indian Ocean mode (PIM) on the interannual variability of the Tibetan Plateau (TP) precipitation in mid‐autumn (October) is investigated. We find that the interannual variation of the mid‐autumn TP precipitation is characterized by a dipole mode with a southeast–northwest inverse pattern, which is influenced significantly by the large‐scale circulation anomalies induced by PIM. During a positive phase of PIM, that is, positive SSTA in both the tropical central‐eastern Pacific and western Indian Ocean accompanied by negative SSTA around the Maritime Continent, a robust lower‐level anticyclonic anomaly over the South Asia region (SAAC) and an upper‐level cyclonic anomaly over subtropical Asia are generated owing to the Rossby wave response to the suppressed convective heating over the northern Maritime Continent. As a result, the southerly (northerly) anomalies on the west (east) side of the SAAC can enhance (reduce) the transportation of moisture and the ascending motion over the northwestern (southeastern) TP. Meanwhile, the southward‐shifted East Asian westerly jet can further enhance the ascending motion over the northwestern TP by stimulating secondary circulation. Correspondingly, a positive (negative) precipitation anomaly appears over the northwestern (southeastern) TP. During a negative phase of PIM, the opposite case is also true. Therefore, the suppressed convective heating over the Maritime Continent serves as a pivotal medium by which PIM affects the TP precipitation in mid‐autumn.
Tree-based machine learning performed in-memory with memristive analog CAM
Authors: Pedretti Giacomo , Graves Catherine E. , Serebryakov Sergey , Mao Ruibin , Sheng Xia , Foltin Martin , Li Can , Strachan John Paul
Published: October 2021

Tree-based machine learning techniques, such as Decision Trees and Random Forests, are top performers in several domains as they do well with limited training datasets and offer improved interpretability compared to Deep Neural Networks (DNN). However, these models are difficult to optimize for fast inference at scale without accuracy loss in von Neumann architectures due to non-uniform memory access patterns. Recently, we proposed a novel analog content addressable memory (CAM) based on emerging memristor devices for fast look-up table operations. Here, we propose for the first time to use the analog CAM as an in-memory computational primitive to accelerate tree-based model inference. We demonstrate an efficient mapping algorithm leveraging the new analog CAM capabilities such that each root to leaf path of a Decision Tree is programmed into a row. This new in-memory compute concept for enables few-cycle model inference, dramatically increasing 103 × the throughput over conventional approaches.
A plastid two-pore channel essential for inter-organelle communication and growth of Toxoplasma gondii
Authors: Li Zhu-Hong , King Thayer P. , Ayong Lawrence , Asady Beejan , Cai Xinjiang , Rahman Taufiq , Vella Stephen A. , Coppens Isabelle , Patel Sandip , Moreno Silvia N. J.
Published: October 2021

Two-pore channels (TPCs) are a ubiquitous family of cation channels that localize to acidic organelles in animals and plants to regulate numerous Ca2+-dependent events. Little is known about TPCs in unicellular organisms despite their ancient origins. Here, we characterize a TPC fromToxoplasma gondii, the causative agent of toxoplasmosis. TgTPC is a member of a novel clad of TPCs in Apicomplexa, distinct from previously identified TPCs and only present in coccidians. We show that TgTPC localizes not to acidic organelles but to the apicoplast, a non-photosynthetic plastid found in most apicomplexan parasites. Conditional silencing of TgTPC resulted in progressive loss of apicoplast integrity, severely affecting growth and the lytic cycle. Isolation of TPCnullmutants revealed a selective role for TPCs in replication independent of apicoplast loss that required conserved residues within the pore-lining region. Using a genetically-encoded Ca2+indicator targeted to the apicoplast, we show that Ca2+signals deriving from the ER but not from the extracellular space are selectively transmitted to the lumen. Deletion of theTgTPC genecaused reduced apicoplast Ca2+uptake and membrane contact site formation between the apicoplast and the ER. Fundamental roles for TPCs in maintaining organelle integrity, inter-organelle communication and growth emerge.
Electron penetration triggering interface activity of Pt-graphene for CO oxidation at room temperature
Authors: Wang Yong , Ren Pengju , Hu Jingting , Tu Yunchuan , Gong Zhongmiao , Cui Yi , Zheng Yanping , Chen Mingshu , Zhang Wujun , Ma Chao , Yu Liang , Yang Fan , Wang Ye , Bao Xinhe , Deng Dehui
Published: October 2021

Achieving CO oxidation at room temperature is significant for gas purification but still challenging nowadays. Pt promoted by 3dtransition metals (TMs) is a promising candidate for this reaction, but TMs are prone to be deeply oxidized in an oxygen-rich atmosphere, leading to low activity. Herein we report a unique structure design of graphene-isolated Pt from CoNi nanoparticles (PtǀCoNi) for efficiently catalytic CO oxidation in an oxygen-rich atmosphere. CoNi alloy is protected by ultrathin graphene shell from oxidation and therefore modulates the electronic property of Pt-graphene interface via electron penetration effect. This catalyst can achieve near 100% CO conversion at room temperature, while there are limited conversions over Pt/C and Pt/CoNiOxcatalysts. Experiments and theoretical calculations indicate that CO will saturate Pt sites, but O2can adsorb at the Pt-graphene interface without competing with CO, which facilitate the O2activation and the subsequent surface reaction. This graphene-isolated system is distinct from the classical metal-metal oxide interface for catalysis, and it provides a new thought for the design of heterogeneous catalysts.
Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection
Authors: Ferren Marion , Favède Valérie , Decimo Didier , Iampietro Mathieu , Lieberman Nicole A. P. , Weickert Jean-Luc , Pelissier Rodolphe , Mazelier Magalie , Terrier Olivier , Moscona Anne , Porotto Matteo , Greninger Alexander L. , Messaddeq Nadia , Horvat Branka , Mathieu Cyrille
Published: October 2021

SARS-CoV-2 has caused a global pandemic of COVID-19 since its emergence in December 2019. The infection causes a severe acute respiratory syndrome and may also spread to central nervous system leading to neurological sequelae. We have developed and characterized two new organotypic cultures from hamster brainstem and lung tissues that offer a unique opportunity to study the early steps of viral infection and screening antivirals. These models are not dedicated to investigate how the virus reaches the brain. However, they allow validating the early tropism of the virus in the lungs and demonstrating that SARS-CoV-2 could infect the brainstem and the cerebellum, mainly by targeting granular neurons. Viral infection induces specific interferon and innate immune responses with patterns specific to each organ, along with cell death by apoptosis, necroptosis, and pyroptosis. Overall, our data illustrate the potential of rapid modeling of complex tissue-level interactions during infection by a newly emerged virus.