bluuebunny/crossref_metadata_2025 huggingface dataset:
GIS-based landslide susceptibility mapping using bivariate statistical methods in North-western Tunisia
Authors: Anis Zorgati , Wissem Gallala , Vali Vakhshoori , Smida Habib , Mohamed Essghaier Gaied
Published: November 2019

The Tunisian North-western region, especially Tabarka and Ain-Drahim villages, presents many landslides every year. Therefore, the landslide susceptibility mapping is essential to frame zones with high landslide susceptibility, to avoid loss of lives and properties. In this study, two bivariate statistical models: the evidential belief functions (EBF) and the weight of evidence (WoE), were used to produce landslide susceptibility maps for the study area. For this, a landslide inventory map was mapped using aerial photo, satellite image and extensive field survey. A total of 451 landslides were randomly separated into two datasets: 316 landslides (70%) for modelling and 135 landslides (30%) for validation. Then, 11 landslide conditioning factors: elevation, slope, aspect, lithology, rainfall, normalized difference vegetation index (NDVI), land cover/use, plan curvature, profile curvature, distance to faults and distance to drainage networks, were considered for modelling. The EBF and WoE models were well validated using the Area Under the Receiver Operating Characteristic (AUROC) curve with a success rate of 87.9% and 89.5%, respectively, and a predictive rate of 84.8% and 86.5%, respectively. The landslide susceptibility maps were very similar by the two models, but the WoE model is more efficient and it can be useful in future planning for the current study area.
Deformation monitoring and prediction for residential areas in the Panji mining area based on an InSAR time series analysis and the GM-SVR model
Authors: Li Jinchao , Gao Fei , Lu Jiaguo , Tao Tingye
Published: November 2019

Underground coal mining activities often cause ground subsidence and damage to surface construction, which seriously threatens the lives and property of residents in mining areas. In this paper, the deformation of the Yang Juzhuang village, which is a residential area in the Huainan mining area (China), was monitored through an interferometric synthetic aperture radar (InSAR) time series analysis. The vertical displacements were detected using thirteen Sentinel-1A images that were acquired between December 2016 and May 2017. The validity and applicability of the method are verified by comparing the acquired images with the GPS measurement results. Because of the deformation characteristics of the mining area, a prediction model that is combined with a grey support vector machine regression (GM-SVR) is proposed, and the practical effects of the model are verified using the deformation monitoring results of the study area. The combination of this model and SBAS-InSAR provides rapid dynamic monitoring and enables the issuance of disaster warnings in the region.
Statistical and expert-based landslide susceptibility modeling on a national scale applied to North Macedonia
Authors: Milevski Ivica , Dragićević Slavoljub , Zorn Matija
Published: November 2019

This article presents a Geographic Information System (GIS) assessment of Landslide Susceptibility Zonation (LSZ) in North Macedonia. Because of the weak landslide inventory, statistical method (frequency ratio) is combined with Analytical Hierarchy Process (AHP). In this study, lithology, slope, plan curvature, precipitations, land cover, distance from streams, and distance from roads were selected as precondition factors for landslide occurrence. There are two advantages of the approach used. The first is the possibility of comparing of the results and cross-validation between the statistical and expert based methods with an indication of the advantages and drawbacks of each of them. The second is the possibility of better weighting of precondition factors for landslide occurrence, which can be useful in cases of weak landslide inventory. The final result shows that in the case of weak landslide inventory, LSZmap created with the combination of both models provide better overall results than each model separately.
Performance Analysis of FSK-PPM Technique in Visible-Light Communication Systems
Authors: Sönmez Mehmet
Published: November 2019

This paper presents a combination of the FSK (frequency shift keying) and the PPM (pulse position modulation) techniques for visible-light communication systems. We propose novel modulator architecture, which is referred as combined FSK-PPM (CFPPM), to observe the average power requirement of FSK technique. The proposed combined scheme is compared with the traditional FSK method in terms of average transmission power and BER (bit error rate) performance. The average transmission power of FSK modulation technique is independent on M that is expressed as modulation order. The results show that the requirement of average transmission power of proposed FSK can be gradually decreased dependent on M.
Multi-Layer Graded-Index Planar Structure for Coarse WDM Demultiplexing
Authors: Bany Salameh Haythem , Khrais Hazem
Published: November 2019

In this paper, we develop a novel demultiplexer design for Coarse Wavelength Division Multiplexer (CWDM). The device consists of multi-layer inhomogeneous semi-conductor material, where the refractive index of each layer is graded according to a predefined profile. The proposed design exploits the ray’s spatial shift that results from the material dispersion as different wavelengths propagate through the different layers of the device. Our design forces the multiplexed light to refract after propagation for short distance within the device leading to smaller device size while providing the needed spatial shift between the ray’s of the adjacent multiplexed wavelengths. The proposed structure can be easily implemented using the well-established technology utilized in fabricating existing graded-index fibers. The impacts of the various design parameters (such as the incident angle, number of layers, the layer thickness, the spacing between adjacent wavelengths, the refractive index difference) on the amount of achieved spatial shift between the adjacent wavelengths and the size of the device are investigated. Compared to previous proposed techniques, our device can be easily fabricated to provide higher spatial shift while reducing the device size with by controlling the different design parameters.
Crystal structure of hexacarbonyl-(μ2-methanoato-k2
O:O′)-(μ2–bis(di-p-tolylphosphino)cyclohexylamine-κ2
P:P′)dirhenium(I), C42H45NO8P2Re2
Authors: Kama Dumisani V. , Brink Alice , Alberto Roger , Roodt Andreas
Published: November 2019

C42H45NO8P2Re2, monoclinic, C2/c (no. 15), a = 24.1612(7) Å, b = 13.0229(3) Å, c = 14.9180(4) Å, β = 121.383(3)°, V = 4007.2(2) Å3, Z = 4, R
gt(F) = 0.0235, wR
ref(F
2) = 0.0596, T = 173(2) K.
Crystal structure of catena-[(bis(O,O′-diethyl dithiophosphato-S,S′)-μ2-1,2-bis(4-pyridylmethylene)hydrazine-N,N′)cadmium(II)], {C20H30CdN4O4P2S4}n
Authors: Tan Yee Seng , Tiekink Edward R.T.
Published: November 2019

C20H30CdN4O4P2S4, triclinic, P1̄ (no. 2), a = 9.3353(2) Å, b = 9.7725(2) Å, c = 10.6884(2) Å, α = 63.153(2)°, β = 64.193(2)°, γ = 62.710(2)°, V = 740.43(3) Å3, Z = 1, R
gt(F) = 0.0171, wR
ref(F
2) = 0.0465, T = 100 K.
The crystal structure of the triclinic polymorph of hexameric (trimethylsilyl)methyllithium, C24H66Li6Si6
Authors: Bauer Jonathan O.
Published: November 2019

C24H66Li6Si6, triclinic, P1̄ (no. 2), a = 12.2492(9) Å, b = 12.4617(9) Å, c = 14.3841(11) Å, α = 74.189(6), β = 74.543(7), γ = 85.970(6), V = 2036.2(3) Å3, Z = 2, R
gt(F) = 0.0465, wR
ref(F
2) = 0.0802, T = 173(2) K.
The crystal structure of 3-((1R,2S)-1-methylpyrrolidin-1-ium-2-yl)pyridin-1-ium tetrachloridomanganate(II), C10H16Cl4MnN2
Authors: Reiss Guido J.
Published: November 2019

C10H16Cl4MnN2, monoclinic, P21 (no. 4), a = 7.28276(7) Å, b = 13.22972(12) Å, c = 8.01007(7) Å, β = 97.5018(9)°, V = 765.155(12) Å3, Z = 2, R
gt(F) = 0.0165, wR
ref(F
2) = 0.0392, T = 123(2) K.
Magnetic and electronic properties of CaFeO2Cl
Authors: Rendenbach Bettina , Klenner Steffen , Pöttgen Rainer , Johrendt Dirk
Published: November 2019

CaFeO2Cl is a unique exception in the family of the iron oxyhalides. Its crystal structure is not related to the Ruddlesden-Popper phases as known for the other members, but contains layers of edge-sharing FeO2/2O3/3 pyramids without Fe–Cl contacts. The iron atoms form a distorted honeycomb substructure. Magnetization measurements on single crystals show an unexpected weak anisotropy and indicate antiferromagnetic ordering of the iron magnetic moments already at room temperature. 57Fe Mössbauer spectra confirm the trivalent oxidation state of iron and the presence of magnetic order. DFT calculations using the LDA + U approach support a Mott-insulating antiferromagnetic ground state and indicate a Néel-type ordered antiferromagnetic state in the honeycomb layer. The band gap from optical measurements is 1.3 eV and agrees with the red-brown colour as well as with the theoretical calculations.
The Effect of Personal Protective Equipment on Firefighter Occupational Performance
Authors: Lesniak Ashley Y. , Bergstrom Haley C. , Clasey Jody L. , Stromberg Arnold J. , Abel Mark G.
Published: November 2019

Lesniak, AY, Bergstrom, HC, Clasey, JL, Stromberg, AJ, and Abel, MG. The effect of personal protective equipment on firefighter occupational performance. J Strength Cond Res 34(8): 2165–2172, 2020—The purpose of this study was to evaluate the effects of load carriage (LC) and LC plus respirator use (LC + self-contained breathing apparatus [SCBA]) on firefighters' work capacity to enhance our understanding of occupational demands. Twenty-one male structural firefighter recruits (age: 28.6 ± 4.3 years; height: 178.6 ± 7.2 cm; body mass: 94.1 ± 15.4 kg; body fat: 22.9 ± 6.1%) participated. Occupational performance was assessed by time to complete a simulated fire ground test (SFGT). After 2 familiarization trials, recruits performed the following SFGT conditions in a randomized order: PT (physical training clothes), LC only, and LC + SCBA. To describe within-group differences between SFGT conditions, relative difference scores were calculated as follows: % difference = ([experimental trial outcome − PT trial outcome]/PT trial outcome) × 100. Statistical differences between conditions were assessed with repeated-measures analysis of variance. The level of significance was set p < 0.01. Time to complete the LC + SCBA trial (345.9 ± 43.7 seconds; p < 0.001) and LC-only trial (331.2 ± 39.3 seconds; p < 0.001) were significantly greater than the PT trial (241.0 ± 33.3 seconds). Post-SFGT rating of perceived exertion was higher in the LC + SCBA trial (6.7 ± 1.7) and LC trial (6.4 ± 1.5) compared with the PT trial (4.7 ± 1.8; p < 0.001). Heart rate and lactate measures were similar across conditions (p = 0.488; p = 0.287). Personal protective equipment (PPE) significantly decreases the work capacity and increases the perceived effort of occupational tasks. Thus, these findings describe the additional physical demands produced by PPE and indicate that performance of firefighting tasks in an unloaded condition does not reflect work capacity in a bona fide condition.
Evaluating Concrete Damage in Bridge Decks with and without Overlays Using Nondestructive Testing Procedures
Authors: Robison Tyler W. , Barnes Christopher L. , Tinkey Yajai , Tanner Jennifer E.
Published: November 2019

The state of Wyoming alone has 13.1 million square feet of bridge deck, and evaluation of those decks has become an important part of the Wyoming Department of Transportation’s (WYDOT) management of bridge repairs. The authors believe that development and advancement of nondestructive evaluation methods over the past 25 years may provide a more efficient, standardized, and accurate method for evaluating bridge deck conditions compared with current practices. A study was performed on three bridge decks in Wyoming: the First Street Bridge in Casper, the Douglas I-25 Bridge, and the Remount I-80 Bridge. For each bridge, an investigation was done using standard WYDOT practices for chain dragging. In addition, the bridges were evaluated using impact echo, thermal imaging, and ground-penetrating radar (GPR) techniques. All three methods considered were successful, and the damage locations between the impact echo, thermal imaging, and GPR generally correlated well. Based on this study, a complete bridge deck evaluation should combine impact echo with GPR testing to provide the most accurate predictions of delamination and debonding in support of optimal maintenance decisions.
Diagnostic Accuracy of Three-Dimensional Whole-Heart Magnetic Resonance Angiography to Detect Coronary Artery Disease with Invasive Coronary Angiography as a Reference: A Meta-Analysis
Authors: Yu Shiqin , Cui Chen , Lu Minjie , Zhao Shihua
Published: November 2019

Objective: We aimed to evaluate the diagnostic performance of three-dimensional whole-heart magnetic resonance coronary angiography (MRCA) in detecting coronary artery disease (CAD) with invasive coronary angiography as the reference standard.

Methods: We searched PubMed and Embase for studies evaluating the diagnostic performance of three-dimensional whole-heart MRCA for the diagnosis of CAD with invasive coronary angiography as the reference standard. The bivariate mixed-effects regression model was applied to synthesize available data. The clinical utility of whole-heart MRCA was calculated by the posttest probability based on Bayes’s theorem.

Results: Eighteen studies were included, of which 16 provided data at the artery level. Patient-based analysis revealed a pooled sensitivity of 0.90 (95% confidence interval [CI] 0.87–0.93) and specificity of 0.79 (95% CI 0.73–0.84), while the pooled estimates were 0.86 (95% CI 0.82–0.89) and 0.89 (95% CI 0.84–0.92), respectively, at the artery level. The areas under the summary receiver operating characteristic curve were 0.93 (95% CI 0.90–0.95) and 0.92 (95% CI 0.90–0.94) at the patient and artery levels, respectively. With a pretest probability of 50%, the patients’ posttest probabilities of CAD were 81% for positive results and 11% for negative results.

Conclusions: Whole-heart MRCA can be an alternative noninvasive method for diagnosis and assessment of CAD.
Talk That Talk
Authors: Hunter Matthew
Published: November 2019

This essay draws upon the work of Erving Goffman and Michael Silverstein to read Shakespeare’s first poem as a guide to mastering the burgeoning early modern art of conversation. The epyllion follows the conversation manuals of its day in embracing the aphorism as a charismatic form of talk, but it departs from its precedents in attributing to the aphorism an overtly erotic force. By according to the aphorism the power to turn conversation into an erotic encounter, Venus and Adonis elaborates its period’s most seductive fantasy of talk.
CARM1 is heterogeneous in mouse four-cell embryo and important to blastocyst development
Authors: Sun Hongzheng , Su Jianmin , Wu Teng , Wang Fengyu , Kang Jian , Zhang Jingcheng , Xing Xupeng , Cheng Yuyao , Zhang Yong
Published: November 2019

Coactivator-associated arginine methyltransferase 1 (CARM1) is a type I arginine methyltransferase that methylates the arginine residues of histone and nonhistone. Carm1 regulates various cellular processes, including transcriptional regulation, mRNA processing, cellular proliferation, and differentiation. Blastomeres with high Carm1 expression levels show cleavage tendency to inner cell mass (ICM) in mouse embryos. However, details about the factors for CARM1 distribution in mouse early embryos and the role of Carm1 in blastocyst development remain unclear. Here, the endonuclear distribution of CARM1 protein was heterogeneous between blastomeres from the late four-cell stage to the blastocyst stage. The heterogeneity of CARM1 distribution in blastomeres at the late four-cell stage was randomly obtained from two-cell stage embryos. From the four-cell stage to morula, CARM1 in individual blastomere remained heterogeneous. In the blastocyst stage, CARM1 protein level in ICM was much higher than that in trophoblast. We found that microRNA (miRNA) miR-181a is an important regulator for Carm1 distribution at the late four-cell stage. The ratio of heterogeneous embryos was reduced in all the embryos when miR-181a was inhibited. CARM1 inhibition reduced the level of symmetrical histone H3 arginine-26 dimethylation and impaired blastocyst development. Silencing Carm1 reduced cell number and increased cell apoptosis at the blastocyst stage. These results show a CARM1 heterogeneous distribution from the four-cell embryos to the blastocysts. miR-181a regulates the control of CARM1 heterogeneous distribution in the four-cell-stage embryos, and CARM1 is an important protein in regulating blastocyst development.
Settlement differentiation of vital comfort of population of European countries: a comparative analysis
Authors: Burova Olha
Published: November 2019

The article compares settlement differentiation of vital comfort of European countries. In Western countries, trend growth rates of vital comfort with a decrease in the size of the settlement.
In post-socialist countries, noticeable general trend of growth of these parameters with increasing size of the settlement.
Development of the internal light industry market: challenges and opportunities
Authors: Deyneko Liudmyla , Zavgorodnya Mariia
Published: November 2019

In this article problems and tendencies of the improving of the domestic market of Ukrainian light industry were traced. The factors, which caused reduction of domestic product at the market and worsening of export-import balance, were studied.
Possible ways of improving of the domestic market of light industry and measures of the government regulation to defend and stimulate it were determined.
Institutional and economic problems of formation of business environment in Ukraine
Authors: Melnyk Oleksandr
Published: November 2019

Comparative analysis of institutional and economic problems of formation of the domestic business environment on the basis of rating assignments of leading international organizations and public opinion polls is conducted, summarized the main disadvantages of the organizational and economic conditions of business development.
The directions of combating corruption, improving the regulatory policy and licensing system of the domestic business environment is determined.
Origin and development of finances as the institutions of Ukrainian statehood in the context of political and economic antagonism XVI–XVIII centuries
Authors: Nebrat Viktoriia
Published: November 2019

The article discusses the features of the evolution of financial relations in the Ukrainian lands and defines the character of economic policies of Hetmans. Is justified the thesis that in the process of political and economic confrontation of XVI–XVIII centuries. took place the birth and development of the finances as the institutions of the Ukrainian statehood.
Regional aspects of development of social labour sphere in Ukraine and abroad
Authors: Melnyk Serhii
Published: November 2019

The article determines respective issues of regulation of regional policy in Ukraine and abroad, describes methodical approaches as to determination of depressive regions in EC countries and USA, illustrates the experience of some countries as to levelling of social-economic development, classifies the regions of Ukraine according to levels of social-economic development, submits propositions on their interregional levelling.
Possibilities of influence of civil society institutions on political culture transformation, social mobility of Ukrainian society
Authors: Golovenko Valerii
Published: November 2019

The article defines the possibilities of influence of civil society institutions on social mobility transformation. Is analyzed, how membership in such organizations affects the formation of political culture of citizens.
It is shown that even in conditions of underdeveloped civil society of modern Ukraine, membership in its organization has a positive effect on the transformation of political culture, social mobility of society.
Facing the Other
Authors: Remund Ariel
Published: November 2019

This article examines religious and community leaders’ perceptions of diversity and the ways in which they, and their communities, negotiate difference. Hobart, in Tasmania, Australia, is experiencing growing religious and ethnic diversity that is posing challenges for existing faith communities. The data consists of twelve in-depth interviews with Hobart’s religious leaders in which participants described two modes of negotiating difference: seeking sameness and agreeing to disagree. These modes of negotiation are positive examples of Lori Beaman’s (2014) understanding of agonistic respect in processes of “deep equality”. Growing diversity is, however, causing tensions for some communities, most notably conservative Christians in this study, who perceived growing hostility towards Christianity from secular society. Social issues, including marriage equality, have heightened tensions between conservative Christians and anti-religious Nones (Not Religious). I argue that social cohesion is reliant upon a commitment to liberal democratic values. This commitment provides the capacity for individuals to live with sometimes confronting difference that in turn underlies the celebration of diversity and difference in multiculturalism and pluralism.
Transcending Methodological Atheism and Not Thinking Transcendentally
Authors: Jewdokimow Marcin
Published: November 2019

The main goal of the article is to propose an alternative approach towards the monastery, which relies on overcoming methodological atheism and is rooted in a lived, everyday religion approach. In order to do so, in the first section, I reconstruct Peter Berger’s methodological atheism, discuss its limits, and point to alternative methodological approaches. In the second section I present elements of my sociological study of a female, cloistered monastery, focusing on the dichotomy between obedience and autonomy in nuns’ experiences of life within a cloistered monastery. If understood from a classical perspective, the two traits seem contradictory. My research suggests that some nuns perceive these two characteristics as supplemental rather than contradictory. I propose that using an approach that focuses on lived, everyday religion, rather than an approach focused on religious experience (methodological atheism) allows for a comprehensive interpretation of how monasteries work and how monks and nuns operate in this specific environment. It also allows for the integration of social actors’ understanding of their environment into investigation.
O’Brien, John. Keeping It Halal: The Everyday Lives of Muslim American Teenage Boys
Authors: Van Stee Elena G.
Published: November 2019

O’Brien, John. 2017. Keeping It Halal: The Everyday Lives of Muslim American Teenage Boys. Princeton, NJ: Princeton University Press. xxiii + 216 pp. ISBN: 978-0-6911-6882-1 £24.00 (hbk); 978-0-6911-9711-1 £21.95 (pbk).
ESTRESSE OCUPACIONAL NA MÍDIA IMPRESSA: UMA PERSPECTIVA DE CHRISTOPHE DEJOURS
Authors: Garcia Átala Lotti , Emerich Tatiana Breder , Salaroli Luciane Bresciani , Cavaca Aline Guio , Santos Neto Edson Theodoro dos
Published: November 2019

Resumo O estresse no trabalho afeta os aspectos psicológicos, físicos e sociais do trabalhador, bem como a eficácia das organizações produtivas. O objetivo deste estudo foi compreender o estresse ocupacional na mídia jornalística sob a ótica da organização do trabalho. Trata-se de uma pesquisa qualitativa conduzida por análise de conteúdo de Bardin, com base nas categorias analíticas previamente definidas pela Organização Mundial da Saúde, no relatório “Work Organization & Stress”, sob a perspectiva do referencial teórico de Christophe Dejours. Foram classificadas 727 notícias que tinham como palavra-chave ‘estresse’, sendo 130 notícias específicas do tema estresse no trabalho. Dentre estas notícias, foram classificadas as categorias “Conteúdo dos Riscos do Estresse” (47) e “Contexto dos Riscos do Estresse” (59), ambas com suas subcategorias. Constatou-se que a mídia quase não tem funcionado como porta-voz dos trabalhadores a fim de cumprir seu papel social, sem estimulá-los como sujeitos sociais. Propõe-se que a mídia jornalística estimule ações que impulsionem o protagonismo dos trabalhadores, baseado na visibilidade das legislações vigentes, e aponte caminhos mais diretos para que os trabalhadores possam lutar pela garantia de direitos à saúde no combate ao estresse, com perspectiva crítica do entendimento sobre organização do trabalho e suas potencialidades na promoção da saúde.
Deslimites da Palavra em Manoel de Barros: literatura menor e infância
Authors: Moraes Fabiano de Oliveira , Silva Sandra Kretli da
Published: November 2019

Resumo: Com o intuito de potencializar o devir-nômade que pulsa nas escolas e subversa os currículos, o artigo lança mão dos conceitos de literatura menor, língua menor, desterritorialização, reterritorialização, nomadismo, linhas molares, moleculares e de fuga, espaços liso e estriado, e máquina de guerra nômade (Deleuze, Guattari e Parnet), e de inutileza, inutensílio, infância, invenção, deslimite da palavra e idioleto manoelês (Barros) com o objetivo de problematizar os conceitos de lúdico, brincadeira e seriedade, e provocar possíveis produções de sentido a partir dos balbucios e gaguejos de crianças do 2º Ano em seu processo de reinvenção de uma linguagem estrangeira dentro de uma língua maior, em textos produzidos em uma oficina de leitura.
O gênero Aeschynomene (Leguminosae-Papilionoideae) no estado de Roraima, Brasil
Authors: Hartmann Leonardo da Silva , Rodrigues Rodrigo Schütz , Flores Andréia Silva
Published: November 2019

Resumo Aeschynomene L., como atualmente delimitado, é um gênero pantropical de leguminosas com cerca de 180 espécies, pertencente à subfamília Papilionoideae. Este trabalho apresenta o levantamento dos táxons de Aeschynomene no estado de Roraima, Região Norte do Brasil. Em Roraima, o gênero está representado por 11 espécies: A. americana, A. brasiliana, A. evenia, A. filosa, A. fluminensis, A. histrix, A. interrupta, A. paniculata, A. pratensis, A. rudis e A. sensitiva. As espécies A. rudis e A. evenia são novas ocorrências para a flora do estado. Neste trabalho são fornecidas chaves de identificação, descrições, ilustrações e informações sobre habitats preferenciais para as espécies ocorrentes no estado.
Orthodontic traction of impacted maxillary canines using segmented arch mechanics
Authors: Schroeder Marco Antonio , Schroeder Daniela Kimaid , Capelli Júnior Jonas , Santos Diego Junior da Silva
Published: November 2019

ABSTRACT The principles of orthodontic mechanics strongly influence the success of impacted canine traction. The present study discusses the main imaging exams used for diagnosis and localization of impacted canines, the possible associated etiological factors and the most indicated mechanical solutions.
Práticas de Ciência Aberta da comunidade acadêmica brasileira: estudo a partir da produção científica
Authors: CABALLERO-RIVERO Alejandro , SÁNCHEZ-TARRAGÓ Nancy , SANTOS Raimundo Nonato Macedo dos
Published: November 2019

Resumo A Ciência Aberta representa um novo enfoque para o trabalho científi co, resultante do rápido desenvolvimento de modos interativos e colaborativos de aquisição, produção e disseminação de conhecimento, facilitados pelas tecnologias da informação. O termo é utilizado como “guarda-chuva” que engloba um conjunto de iniciativas, entre elas Acesso Aberto e Dados Abertos. A pesquisa, com enfoque cientométrico, utiliza a produção científi ca brasileira de artigos publicados em periódicos indexados na Web of Science Core Collection, no período 2015-2018, visando explorar as práticas da comunidade acadêmica nacional relacionadas com Acesso Aberto e Dados Abertos. Constata o crescimento estável dos artigos em Acesso Aberto, os quais representam mais de um terço da produção brasileira na Web of Science no período. A publicação em mega journals internacionais de Acesso Aberto constitui uma prática destacada, com ênfase em comunidades que pesquisam as áreas de Agricultura e Ciência & Tecnologia, bem como o depósito em repositório de artigos previamente publicados em periódicos de acesso aberto. Já as práticas relacionadas a Dados Abertos parecem ainda incipientes, e os resultados sugerem que seu uso predomina nas áreas de Ciência & Tecnologia, Parasitologia e Genética & Hereditariedade.
DNA clean-up and size selection for long-read sequencing v2
Authors: Jones Ashley , Purushotham Neeraj , Nasim Jamila , Schwessinger Benjamin
Published: November 2019

DNA extractions often contain impurities which limit the output of long-read sequencing technologies. Here a protocol is provided which removes impurities and size selects for longer fragments. To remove residual RNA and protein, an additional RNAse A and Proteinase K treatment is performed. A clean-up with chloroform: isoamyl alcohol (24:1) removes these proteins and other hydrophobic organics such as lipids. A low volume ethanol precipitation and wash is used to concentrate the DNA, hopefully also reducing polysaccharides. Finally, a Short Read Eliminator (SRE) kit by Circulomics is utilised for size selection, which also appears to clean the DNA. This has been trialled for the sorghum rot fungus Macrophomina phaseolina, providing highly promising results with an Oxford Nanopore MinION. One strain yielded 13.71 Gbases with an N50 of 21.75 kb, another strain yielded 9.72 Gbases with an N50 of 43.50 kb. Similar results are expected across many organisms, but have not been tested.
To the study of herpetofauna of "Yelanetskyi steppe" nature reserve and adjoined territоries
Authors: Nekrasova O. , Marushchak O. , Oskyrko O.
Published: November 2019

As a result of monitoring research conducted in 2015-2017 on the territory of the nature reserve “Yelanetskyi steppe" and adjacent areas, 5 amphibian species (fire-bellied toad, green toad, common spadefoot, marsh frog, H. arborea) and 7 species of reptiles (sand lizard, green lizard, blotched snake, large whipsnake, grass snake, dice snake, pond turtle). The presence of some of the species specified in the project of the reserve creation, namely pond turtle, green lizard, large whipsnake, steppe viper, common toad and common newt has not been confirmed on the reserve's territory. The presence of 8 species was registered directly on the territory of the reserve, and another 4 species were registered in the vicinity of the rivers Gromokliya and Gniloy Yelanets. The most numerous among the identified amphibians are the semi-terrestrial species, such as the common spadefoot and the marsh frog. Sand lizard is the most widespread reptile species within the reserve territory and its population is characterized by an exceptional variety of coloration morphology. It should be noted that for more than a 30-year period a unique numerous population of the blotched snake has been preserved here. According to original data, more than two dozen snake specimens were registered in the vicinity of the Rosa beam. Due to climatic changes, it is proposed to expand the reserve's territory in ecotone river areas where there are finds of blotched snakes and large whipsnakes (RBU, 2009), green lizards (RBU, 2009) and pond turtles (IUCN (LR/NT)) to conserve biodiversity and protect rare species. In
particular, the expansion of the boundaries of the reserve is necessary in the context of climate change, as it leads to a shift in the natural habitats of certain amphibian and reptile species, and is also an important step towards the expansion of the Emerald Network of Ukraine
Metabolomic research in medicine
Authors: Furina R R , Mitrakova N N , Ryzhkov V L , Safiullin I K
Published: November 2019

The paper covers the questions of metabolomic research in medicine. The central idea of metabolomics is to identify the specific biomarkers in biological samples for diagnosis of a number of conditions. The biomarkers include volatile organic compounds - metabolites isolated from various tissues and biological fluids (blood, urine, sputum, exhaled air). Main methods of separation and identification of volatile organic compounds (gas chromatography, mass spectrometry, nuclear magnetic resonance spectroscopy) applied in metabolomics, are reviewed. Mass spectrometry and nuclear magnetic resonance spectroscopy are compared as the main methods of volatile metabolites detection. The method of solid phase microextraction, used for sample preparation, is described. The paper reviews laboratory research results aimed at the detection of cancer, chronic infections and inherited diseases biomarkers. The qualitative characteristics of biological sample metabolome taken from patients with different diseases are discussed. Besides, special attention is paid to the possible use of metabolomics in experimental medicine. The results of volatile metabolome changes in cell culture in vitro depending on the additives to nutrient media, β-carotene volatile decomposition products as suspected carcinogens, volatile organic compounds emitted at vertebrates decay are described. In addition, the method of two-dimensional gas chromatography aimed to increase the sensitivity and specificity of metabolomics tests is portrayed. The presented approach adds to early diagnosis of a number of diseases.
Secondary premature loss of baby teeth in children who had seek for the orthodontic aid
Authors: Ayupova F S
Published: November 2019

Aim. To study the prevalence and structure of secondary premature loss of baby teeth in children of various ages who had seek for orthodontic aid. Methods. 998 medical charts of children aged from 3 to 10 years who were present at the department of pediatric stomatology seeking for orthodontic aid from 2003 to 2012. Groups of children were gender and age-matched. The analysis of prevalence and structure of prematurely extracted temporary teeth was performed. Results. Premature loss of temporary teeth was revealed in 312 (31.27%) out of 998 children who had seek for orthodontic aid. During the period of the temporary bite formation (3-6 years), the number of extracted deciduous incisors and molar teeth increased twice, single cases of deciduous canine teeth loss were revealed. During the mixed bite period, every 4th and/or 5th child had defects of baby tooth arches. Molars, mainly first molars, were the temporary teeth that were extracted more often. Significant increase in prevalence of a secondary premature loss of baby teeth (up to 27.91%), mainly at the lower jaw, was noticed during the period of the eruption of closely located permanent incisor teeth. Combined defects of frontal and lateral areas of temporary tooth arches were revealed in some children. Conclusion. Prevalence of a secondary premature loss of baby teeth in children of Krasnodar Krai who had seek for the orthodontic help, reached 31.27%. Upper incisors, first molar teeth, lower canines and their combination prevailed among the prematurely extracted temporary teeth. No gender differences in prevalence, structure and localization of prematurely extracted teeth according to quadrants of tooth arches were revealed.
Bond strength of restoration materials used for dental ceramics repair
Authors: Mikheeva A A , Bol’shakov G V
Published: November 2019

Aim. To assess the bond strength of composite material to ceramic surface of metal-ceramic-fixed dental prosthesis depending on the type of restoration systems used for chipped porcelain restorations. Methods. Bond strength of restoration material to porcelain coating surface were studied according to ISO 10477 issued at 01.10.2004. The surface of the ceramic-metal plates was polished by different methods depending on the restoration system used. Restorative material was applied using a template. Prepared samples were placed in a testing machine and loaded at a constant crosshead speed of 1±0.3 mm/min before separation, the load F at break was registered by an automatic recorder. Results. Similar bond strength results were revealed for restoration systems not requiring acid pickling of porcelain surface («Cimara», «Ceramic Repair») and restoration system including 9.5% hydrofluoric acid «Porcelain etch silane»: 17.993, 17.774 and 17.896 MPa respectively. Bond strength was much higher (25.278 MPa) if restoration system with 4% hydrofluoric acid was used. «Vertise™ Flow» restorative single-component material also provided significant bond strength - 24.315 MPa. Conclusion. The study showed the possibility of using a single-component restorative material to repair chipped porcelain tile coating metal-ceramic-fixed dental prostheses. For longer life of chipped porcelain tile coating restoration of dental prostheses, the use of restoration systems including 4% hydrofluoric acid is recommended.
The functional state of the endothelium in patients with viral hepatitis and liver cirrhosis
Authors: Chistyakova M V , Govorin A V , Radaeva E V
Published: November 2019

Aim. To study the functional state of endothelium in patients with chronic viral hepatitis and liver cirrhosis and impact of left and right ventricle diastolic malfunction and pulmonary hypertension on endothelial function. Methods. 74 patients with chronic viral hepatitis (group 1), 62 patients with cirrhosis (group 2) and 17 healthy volunteers were examined. Doppler echocardiography and brachial artery ultrasonography with endothelium-dependent vasodilation measurement were performed. Results. Endothelium-dependent vasodilatation was reduced in patients of the 1 stgroup (6.2%), and of the 2 ndgroup (2.2%) compared to the controls (13.8%, р 0.05). Sensitivity coefficient for the brachial artery was measured as 0.31 (0.19; 0.35) in patients with chronic viral hepatitis, 0.25 (0.09; 0.35) in patients with cirrhosis compared to 1.27 (0.72; 1.29) in control group, demonstrating the marked endothelial dysfunction in patients of the 1 stand 2 ndgroups (р 0.05). Moderate pulmonary hypertension was accompanied by a more pronounced endothelium-dependent vasodilation impairment in both groups (р 0.05). In patients with viral hepatitis, endothelial malfunction was less common (62%) compared with patients with liver cirrhosis (85%, p=0.002). Presence of left and right ventricle diastolic malfunction did not influence the endothelial function. Conclusion. In patients with viral hepatitis and cirrhosis, endothelium-dependent vasodilatation is affected depending on the severity of the disease and increased if pulmonary hypertension was present. Presence of left and right ventricle diastolic malfunction did not influence the endothelial function.
Influence of some hormones and collagen metabolism on gastroesophageal reflux disease pathogenesis in children
Authors: Butorina N V , Vakhrushev Ya M , Zaprudnov A M
Published: November 2019

Aim. To study the collagen metabolism and secretion of hormones, and estimate their association in gastroesophageal reflux disease (GERD). Methods. 62 children with gastroesophageal reflux disease were examined. Control group included 32 children. Insulin and cortisol blood levels were determined by electro-chemiluminescence immunoassay (ECLIA), gastrin and somatostatin blood levels were determined by ELISA. Hydroxyproline and sialic acids levels were measured in gastric juice. Results. Esophageal mucosa lesions of different stages were diagnosed in all children with GERD: 36 (58%) children had I stage of esophagitis, 24 (38.7 %) children - II stage, 2 (3.2%) children - III stage. It was revealed that children with GERD demonstrated increased collagen breakdown level in esophageal and gastric mucosa, confirmed by high free hydroxyproline levels (29.6±3.2 μmol/L; p 0,05) and peptin-associated hydroxyproline (25.5±2.1 μmol /L; p 0.01). This collagen breakdown might be possible due to high cortisol level (389±15.5 nmol/L versus 204.4±12.1 nmol/L in control group, р 0.05). Increased insulin level (28.5±3.2 μU/ml vs 9.3±2.5 μU/ml; р 0,05) in patients with GERD might be a compensatory reaction to catabolic processes. Increased level of somatostatin (0.457±0.14 nmol/L; р 0.001) associated with low levels of gastrin (7.2±1.4 nmol/L) was discovered in children with GERD aged 9-12 years. On the contrary, children older than 12 years demonstrated high gastrin levels (18.72±3.2 nmol/L) associated with low levels of somatostatin (0.129±0.09 nmol/L). Conclusion. Influence of cortisol increased blood level on mucosa results in disbalance between aggressive and protective gastroduodenal factors in children with GERD, resulting in collagen breakdown. Increased insulin level signs the stimulation of the protective and adaptation mechanisms in children with GERD.
Mathematical model for predicting the length of hospital stay after performing high-tech operations for arrhythmia correction
Authors: Basova L A , Karyakina O E , Kochorova L V , Martynova N A , Kalinin A G
Published: November 2019

Aim. To create a mathematical model for predicting the length of post-operative treatment after performing high-tech surgeries for arrhythmia treatment. Methods. To predict the in-patient treatment duration after performing high-tech surgeries for arrhythmia treatment, the data set was checked for normality of sample variance distribution and for variability, discriminant function analysis, variability analysis, Kolmogorov-Smirnov test, crosstab Pearson’s chi-squared test were performed. Normally distributed quantitative parameters are presented as M±m (m - standard error). Cross-sectional prospective study including the data of 345 patients aged 20 to 88 years (males 42.0%, females 58.0%) who underwent high-tech surgeries for arrhythmia treatment, was performed for modeling. Results. It was found that the main category of patients who require surgery for cardiac arrhythmia treatment were women aged 61 to 75 years (mean 68±7 years). Pacemaker implantation was the most common surgery type (47.0%, 162 patients), followed by radiofrequency ablation (31.0%, 107 patients) and encircling pulmonary veins isolation (22.0%, 76 patients). It was also found that the presence of postoperative complications after implantation of the pacemaker directly influencing treatment duration, increasing it almost twice fold (to an average of 14.2±5.1 days compared to 7.4±1.2 days in patients without complications, p=0.02). Statistical analysis allowed to identify five levels characte­rizing the duration of in-patient post-operative management. An automated software module for risk assessment in patients admitted for high-tech surgeries for arrhythmia treatment was created basing on the results of the study. The precision of the model reached 87% (mean value 84.7%). Conclusion. An automated software module for predicting the length of in-patient post-operative treatment allows to stratify the risk of post-surgical complications for patients and shows the influence of those risks on the use of hospital beds, medical aid management and funding of high-tech surgeries by obligatory health insurance funds.
Patient satisfaction as a quality criterion of paid ophthalmologic aid
Authors: Lipinskiy D A , Abrosimova M Yu
Published: November 2019

Aim. Conduct a questionnaire survey of in private clinic patients to study the problems of ophthalmologic aid quality. Methods. The survey included 108 patients who filled in a specially designed questionnaire. Typological and variation analysis was performed, relative and mean statistical values were calculated; statistical significance of revealed differences was checked. Results. When choosing a private clinic, young people often rely on advertising, while the older patients - on the opinion of relatives and friends. Patients seek for paid services because they believe in a higher healthcare, with 59.3% of respondents believe that the quality of care is improved if they pay. Services of paid clinics are quite affordable for the majority of the interviewed patients (proposed service cost is moderate, transport accessibility, travelling time and admission queue time are quite acceptable). Generally, consumers gave a positive assessment of the clinic staff and its activities as a whole: the relationship with the doctor was characterized as trustful, attentive and respectful, involving a complete understanding of patient’s problems by the medical staff. Most respondents (92.6%) find their physician a specialist of high qualification. The main reasons for dissatisfaction with paid medical services are discrepancy between price and quality, low treatment effect, which is closely coupled with the staff competence and incorrect behavior of health workers. Conclusion. The conducted survey showed high satisfaction with medical services provided in a private clinic.
Risk factors of urolithiasis in Gusar and Khachmaz districts of Azerbaijan Republic
Authors: Imamverdiyev S B , Husein-zade R T
Published: November 2019

Aim. To assess the risk factors, gender, age and social features of patients with urolithiasis who live in the northern regions of Azerbaijan. Methods. Patients with urolithiasis who live in the northern regions of Azerbaijan and were admitted to the Central Hospitals of Gusar and Khachmaz districts (113 and 81 patients respectively) were included in the study. In Gusar district, 70 (61.95%) male patients and 43 (38.05%) female patients were included, in Khachmaz region, 51 (62.96%) male and 30 (37.04%) female patients were included. Results. In Gusar district, urolithiasis was most commonly found in patients aged from 16 to 30 years and from 41 to 50 years. In Khachmaz district, the highest prevalence of urolithiasis was registered in people aged from 41 to 50 years. In Gusar district, urolithiasis was more common in patient groups with body mass index of 25-29.9 kg/m 2and 30-34.9 kg/m 2. In Khachmaz district, urolithiasis was diagnosed mainly in patients with body mass index of 25-29.9 kg/m 2and 18.5-24.9 kg/m 2; in female patients - mainly in patients with body mass index of 25-29.9 kg/m 2and 30-34.9 kg/m 2). In both districts, urolithiasis mainly occurred in unemployed and white collars. Conclusion. Overweight, aged and elderly, unemployed and white collars are patient categories with highest risk for urolithiasis, which should be considered at prevention.
Social pediatrics: scientometric analysis
Authors: Albitskiy V Yu , Ustinova N V
Published: November 2019

Aim. To identify trends of further development, priorities, challenges and vectors of further research in social pediatrics. Methods. Interpretive content analysis of dissertations in the field of public health and healthcare for the period from 1991 to 2012 was performed. 4194 items were analyzed. Results. At the first stage of the research, it was found that 14.8% of public health dissertations presented during the research period addressed pediatric problems. The next stage included qualitative and quantitative analysis of top-priority topics of social pediatrics in public health dissertations. The analysis of social pediatrics areas included the following categories: (1) studies of social (psychosocial) determinants of children’s health; (2) studies of health condition of children and adolescents in a stressful situation; (3) organization of medical and social aid to children. Studies of social (psychosocial) determinants of children’s health were the most common (35.9 %). Studies of health status of vulnerable children and adolescents had a share of 15% of all studies. 7.6% of studies were devoted to pediatric medical and social aid organization. Conclusion. It is important to facilitate the research in social pediatrics to optimize the scientific data and improve pediatric medical and social aid.