bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of endophytic colonization by entomopathogenic fungi on the behavior and life history of the tobacco peach aphid Myzus persicae var. nicotianae
Authors: Wilberts Liesbet , Vuts József , Caulfield John C. , Thomas Gareth , Birkett Michael A. , Herrera-Malaver Beatriz , Verstrepen Kevin J. , Sobhy Islam S. , Jacquemyn Hans , Lievens Bart
Published: September 2022

Entomopathogenic fungi can adopt an endophytic lifestyle and provide protection against insect herbivores and plant pathogens. So far, most studies have focused onBeauveria bassianato increase plant resistance against abiotic and biotic stresses, while only little is known for other entomopathogenic fungi. In this study, we investigated whether root inoculation of sweet pepper (Capsicum annuumL.) by the entomopathogenic fungiAkanthomyces muscariusARSEF 5128 andB.bassianaARSEF 3097 can improve resistance against the tobacco peach aphidMyzus persicaevar.nicotianae. First, dual-choice experiments were performed to test the hypothesis that the fungi deter aphids via modifying plant volatile profiles. Next, we tested the hypothesis that endophytic colonization negatively affects aphid life history traits, such as fecundity, development and mortality rate. Aphids were significantly attracted to the odor of plants inoculated withA.muscariusover non-inoculated plants. Plants inoculated withA.muscariusemitted significantly higher amounts of β-pinene than non-inoculated plants, and significantly higher amounts of indole thanB.bassiana-inoculated and non-inoculated plants. Inoculation with the fungal strains also caused significantly higher emission of terpinolene. Further, both aphid longevity and fecundity were significantly reduced by 18% and 10%, respectively, when feeding on plants inoculated withA.muscarius, although intrinsic rate of population increase did not differ between inoculated and non-inoculated plants. Sweet pepper plants inoculated withB.bassianaARSEF 3097 did not elicit a significant behavioral response nor affected the investigated life history traits. We conclude that endophytic colonization by entomopathogenic fungi has the potential to alter olfactory behavior and performance ofM.persicaevar.nicotianae, but effects are small and depend on the fungal strain used.
Gene expression in meningeal lymphatic endothelial cells following traumatic brain injury in mice
Authors: Shimada Ryo , Tatara Yuki , Kibayashi Kazuhiko
Published: September 2022

Meningeal lymphatic vessels transport both the cerebrospinal fluid and interstitial fluid to the deep cervical lymph nodes. Traumatic brain injury (TBI) is accompanied by meningeal injury. We hypothesized that the TBI-induced meningeal injury would damage lymphatic vessels and affect brain function. We observed altered gene expression in meningeal lymphatic endothelial cells (LECs) in a mouse model of TBI. Through flow cytometry–based cell sorting, meningeal LECs were obtained from a mouse model of controlled cortical impact 3 days after TBI. Microarray analysis, real-time polymerase chain reaction assays, and enzyme-linked immunosorbent assays were performed to determine mRNA and protein expression levels in meningeal LECs. The number of meningeal LECs was significantly lower in the injury group than in the sham group 3 days after TBI. Additionally, the mRNA expression of lymphatic vessel endothelial hyaluronan receptor 1 (a specific marker of lymphatic vessels) in meningeal LECs was significantly lower in the injury group than in the sham group. The mRNA and protein expression of FMS-like tyrosine kinase 4 and neuropilin 2 (markers of lymphangiogenesis) in meningeal LECs was significantly higher in the injury group than in the sham group. Our findings indicate that TBI is associated with the impairment of meningeal LECs and meningeal lymphangiogenesis, which implicates lymphatic vessel injury in the pathogenesis of this condition.
Trends and geographical variation in mortality from coronary disease in Peru
Authors: Chambergo-Michilot Diego , Atamari-Anahui Noé , Segura-Saldaña Pedro , Brañez-Condorena Ana , Alva-Diaz Carlos , Espinoza-Alva Daniel
Published: September 2022

Background

Coronary disease (CD) is the main cause of mortality worldwide. Data about trends and geographical variation in CD mortality is available in some American countries. This information varies among countries since CD risk factors frequencies vary.

Objective

To describe the trend and geographical variation of coronary disease (CD) mortality in Peru, 2005–2017.

Methods

Analysis of secondary data of the Peruvian Ministry of Health’s registry of deaths. We analyzed CD mortality. We described the absolute and relative frequency of deaths and age-standardized mortality rate (ASMR) by natural regions, departments, age, sex, and year. We also described the change of ASMR between two periods (2005–2010 vs. 2011–2017).

Results

There were 64,721 CD deaths between 2005 and 2017 (4.12% among all deaths). The absolute frequency of CD deaths was 5,665 and 6,565 in 2005 and 2017, respectively. CD mortality was more frequent in men and older adults. The ASMR varied among natural regions, being higher in the Coast (19.61 per 100,000 inhabitants). The change between the two periods revealed that almost all departments reduced their ASMRs, except for Callao, Lambayeque, and Madre de Dios.

Conclusion

CD mortality has increased in Peru. Mortality was higher in men and older adults, and it varied among departments. More political efforts are needed to reduce these trends.
Fezf2-positive fork cell-like neurons in the mouse insular cortex
Authors: Taniguchi Manabu , Iwahashi Misaki , Oka Yuichiro , Tiong Sheena Y. X. , Sato Makoto
Published: September 2022

The fork cell and von Economo neuron, which are found in the insular cortex and/or the anterior cingulate cortex, are defined by their unique morphologies. Their shapes are not pyramidal; the fork cell has two primary apical dendrites and the von Economo neurons are spindle-shaped (bipolar). Presence of such neurons are reported only in the higher animals, especially in human and great ape, indicating that they are specific for most evolved species. Although it is likely that these neurons are involved in higher brain function, lack of results with experimental animals makes further investigation difficult. We here ask whether equivalent neurons exist in the mouse insular cortex. In human, Fezf2 has been reported to be highly expressed in these morphologically distinctive neurons and thus, we examined the detailed morphology of Fezf2-positive neurons in the mouse brain. Although von Economo-like neurons were not identified, Fezf2-positive fork cell-like neurons with two characteristic apical dendrites, were discovered. Examination with electron microscope indicated that these neurons did not embrace capillaries, rather they held another cell. We here term such neurons as holding neurons. We further observed several molecules, including neuromedin B (NMB) and gastrin releasing peptide (GRP) that are known to be localized in the fork cells and/or von Economo cells in human, were localized in the mouse insular cortex. Based on these observations, it is likely that an equivalent of the fork cell is present in the mouse.
Distraction by violation of sensory predictions: Functional distinction between deviant sounds and unexpected silences
Authors: Parmentier Fabrice B. R. , Leiva Alicia , Andrés Pilar , Maybery Murray T.
Published: September 2022

It has been established that participants performing a continuous categorization task respond significantly slower following the presentation of unexpected, task-irrelevant, auditory stimuli, compared to a repetitive (standard) sound. Evidence indicates that such distraction emerges because of the violation of sensory predictions. This has typically been studied by measuring the impact of replacing the repeated sound by a different sound on rare and unpredictable trials. Here, we examine the impact of a different type of violation: the mere omission of the standard sound. Capitalizing upon the recent finding that deviant sounds exert distinct effects on response times as a function of whether participants produced or withheld a response on the previous trial, we present the results of an experiment seeking to disentangle two potential effects of sound omission: deviance distraction and the removal of an unspecific warning signal. The results indicate that deviant sound and the unexpected omission of the standard sound impact response times through, at least partially, distinct mechanisms. Deviant sounds affect performance by triggering the orienting of attention towards a new sensory input. Sound omissions, in contrast, appear to affect performance in part because responses no longer benefit from an unspecific warning signal to prepare for action.
A joint ventricle and WMH segmentation from MRI for evaluation of healthy and pathological changes in the aging brain
Authors: Atlason Hans E. , Love Askell , Robertsson Vidar , Blitz Ari M. , Sigurdsson Sigurdur , Gudnason Vilmundur , Ellingsen Lotta M.
Published: September 2022

Age-related changes in brain structure include atrophy of the brain parenchyma and white matter changes of presumed vascular origin. Enlargement of the ventricles may occur due to atrophy or impaired cerebrospinal fluid (CSF) circulation. The co-occurrence of these changes in neurodegenerative diseases and in aging brains often requires investigators to take both into account when studying the brain, however, automated segmentation of enlarged ventricles and white matter hyperintensities (WMHs) can be a challenging task. Here, we present a hybrid multi-atlas segmentation and convolutional autoencoder approach for joint ventricle parcellation and WMH segmentation from magnetic resonance images (MRIs). Our fully automated approach uses a convolutional autoencoder to generate a standardized image of grey matter, white matter, CSF, and WMHs, which, in conjunction with labels generated by a multi-atlas segmentation approach, is then fed into a convolutional neural network to parcellate the ventricular system. Hence, our approach does not depend on manually delineated training data for new data sets. The segmentation pipeline was validated on both healthy elderly subjects and subjects with normal pressure hydrocephalus using ground truth manual labels and compared with state-of-the-art segmentation methods. We then applied the method to a cohort of 2401 elderly brains to investigate associations of ventricle volume and WMH load with various demographics and clinical biomarkers, using a multiple regression model. Our results indicate that the ventricle volume and WMH load are both highly variable in a cohort of elderly subjects and there is an independent association between the two, which highlights the importance of taking both the possibility of enlarged ventricles and WMHs into account when studying the aging brain.
Multiplex short tandem repeat profiling of immortalized hepatic stellate cell line Col-GFP HSC
Authors: Meurer Steffen K. , Brenner David A. , Weiskirchen Ralf
Published: September 2022

Misidentification, cross-contamination and genetic drift of continuous animal cell lines are persistent problems in biomedical research, leading to erroneous results and inconsistent or invalidated studies. The establishment of immortalized hepatic stellate cell line Col-GFP HSC was reported in PLoS One in the year 2013. In the present study a multi loci short tandem repeat signature for this cell line was established that allows for unique cell line authentication.
Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model
Authors: Wing Peter A. C. , Prange-Barczynska Maria , Cross Amy , Crotta Stefania , Orbegozo Rubio Claudia , Cheng Xiaotong , Harris James M. , Zhuang Xiaodong , Johnson Rachel L. , Ryan Kathryn A. , Hall Yper , Carroll Miles W. , Issa Fadi , Balfe Peter , Wack Andreas , Bishop Tammie , Salguero Francisco J. , McKeating Jane A.
Published: September 2022

Understanding the host pathways that define susceptibility to Severe-acute-respiratory-syndrome-coronavirus-2 (SARS-CoV-2) infection and disease are essential for the design of new therapies. Oxygen levels in the microenvironment define the transcriptional landscape, however the influence of hypoxia on virus replication and disease in animal models is not well understood. In this study, we identify a role for the hypoxic inducible factor (HIF) signalling axis to inhibit SARS-CoV-2 infection, epithelial damage and respiratory symptoms in the Syrian hamster model. Pharmacological activation of HIF with the prolyl-hydroxylase inhibitor FG-4592 significantly reduced infectious virus in the upper and lower respiratory tract. Nasal and lung epithelia showed a reduction in SARS-CoV-2 RNA and nucleocapsid expression in treated animals. Transcriptomic and pathological analysis showed reduced epithelial damage and increased expression of ciliated cells. Our study provides new insights on the intrinsic antiviral properties of the HIF signalling pathway in SARS-CoV-2 replication that may be applicable to other respiratory pathogens and identifies new therapeutic opportunities.
Components of the LINC and NPC complexes coordinately target and translocate a virus into the nucleus to promote infection
Authors: Spriggs Chelsey C. , Cha Grace , Li Jiaqian , Tsai Billy
Published: September 2022

Nuclear entry represents the final and decisive infection step for most DNA viruses, although how this is accomplished by some viruses is unclear. Polyomavirus SV40 transports from the cell surface through the endosome, the endoplasmic reticulum, and the cytosol from where it enters the nucleus to cause infection. Here we elucidate the nuclear entry mechanism of SV40. Our results show that cytosol-localized SV40 is targeted to the nuclear envelope by directly engaging Nesprin-2 of the linker of nucleoskeleton and cytoskeleton (LINC) nuclear membrane complex. Additionally, we identify the NUP188 subunit of the nuclear pore complex (NPC) as a new Nesprin-2-interacting partner. This physical proximity positions the NPC to capture SV40 upon release from Nesprin-2, enabling the channel to facilitate nuclear translocation of the virus. Strikingly, SV40 disassembles during nuclear entry, generating a viral genome-VP1-VP3 subcomplex that efficiently crosses the NPC to enter the nucleus. Our results reveal how two major nuclear membrane protein complexes are exploited to promote targeting and translocation of a virus into the nucleus.
APAKAH RELIGIUSITAS KEISLAMAN MEMPENGARUHI KETIMPANGAN PENDAPATAN? BUKTI DATA PANEL DARI PROVINSI ACEH
Authors: Amri Khairul , Adi A. Rahmat
Published: September 2022

Penelitian ini menganalisis pengaruh religiusitas keislaman terhadap distribusi pendapatan. Religiusitas diproksikan dengan tiga indikator pengukuran, yaitu jumlah masjid, pesantren, dan santri. Menggunakan dataset panel 23 kabupaten/kota di Aceh dari tahun 2010 hingga 2017, model analisis data yang digunakan adalah regresi panel metode fixed-effect. Hasil penelitian menemukan bahwa pesantren dan santri berpengaruh positif terhadap ketimpangan pendapatan. Sebaliknya, keberadaan masjid tidak mempengaruhi ketimpangan pendapatan. Hasil uji kausalitas Granger memberikan informasi statistik kausalitas satu arah dari ketimpangan pendapatan ke masjid dan pesantren dan dari masjid dan santri ke pesantren. Namun, tidak ada kausalitas dari ketiga dimensi religiusitas keislaman terhadap ketimpangan pendapatan. Informasi statistik ini menunjukkan bahwa, dalam jangka pendek, perubahan religiusitas Islam di Aceh merupakan respons terhadap perubahan ketimpangan pendapatan. Di sisi lain, ketimpangan pendapatan tidak merespon perubahan religiusitas keislaman.
Memahami Generasi Pasca Millenial: Sebuah Tinjauan Praktik Pembelajaran Siswa
Authors: Rakhmah Diyan Nur
Published: September 2022

Selepas era Generasi Millenial berakhir, generasi baru mulai bersiap untuk berperan penuh dalam berbagai urusan dalam kehidupan masa depan. Mereka adalah Generasi Z dan Alpha atau Generasi Pasca Millenial. Generasi ini mulai menyerbu dunia kerja, namun tidak banyak pihak yang paham  secara utuh bagaimana memperlakukan mereka nantinya dengan didasarkan pada bagaimana mereka nanti bekerja, berinteraksi dan membangun komunikasi dalam dunianya. Umumnya Generasi Pasca Millenial saat ini masih duduk di bangku sekolah, mempersiapkan diri memasuki era masa depan dengan segala tantangannya. Pendidikan sebagai bagian yang tidak terlepaskan dalam pembangunan, belum sepenuhnya dijalankan dengan mengakomodir kebutuhan generasi tersebut oleh karena tidak selalu dipraktikkan melalui pendekatan-pendekatan yang berkaitan dengan karakteristik generasi tersebut. Pemahaman lebih mendalam tentang karakteristik generasi ini perlu menjadi perhatian banyak pihak, agar praktik-praktik pembelajaran di dalam kelas, mampu benar-benar menjawab kebutuhan  mereka akan belajar. Pembelajaran dapat disesuaikan dengan karakter generasi tersebut, yaitu identitas yang sulit didefinisikan karena sering berubah-ubah (Undefined ID), menyenangi kehidupan bersama dengan komunitasnya (Communalholic), dan bersifat realistis memandang kehidupan (Realistic). Kemajuan teknologi dan informasi, menjadi salah satu sebab, mengapa karakteristik Generasi Pasca Millenial sangat jauh berbeda dengan generasi-generasi sebelumnya, serta bagaimana mereka menjalankan kehidupannya kelak. Studi kepustakaan terhadap literatur dan publikasi tentang apa dan bagaimana Generasi Pasca Millenial dipahami, menjadi dasar melakukan analisis, sehingga diharapkan mampu  memberikan perspektif berbeda tentang bagaimana mempersiapkan mereka menghadapi masa depan melalui instrumen pendidikan. Tulisan ini bertujuan untuk menawarkan gagasan konseptual tentang praktik-praktik pembelajaran di dalam kelas yang didasarkan pada karakteristik Generasi Pasca Millenial.
Memahami kualitas sumber daya manusia OAP berdasarkan pendekatan people-centered : Studi di Kabupaten Tambrauw dan Sorong
Authors: Surtiari Gusti Ayu Ketut , Romdiati Haning , Katherina Luh Kitty , Kusumaningrum Dwiyanti , Prasojo Ari Purwanto Sarwo
Published: September 2022

Kualitas sumber daya manusia Orang Asli Papua saat ini belum banyak dibahas. Indeks Pembangunan Manusia yang selama ini digunakan sebagai alat ukur untuk mengetahui  gambaran kualitas sumber daya manusia merupakan gambaran agregat di tingkat provinsi. Berdasarkan angka Indeks Pembangunan Manusia atau IPM, Provinsi Papua Barat dan Papua merupakan terendah di Indonesia. Pertanyaannya adalah apakah hal tersebut menunjukkan kualitas sumber daya manusia OAP memang rendah dan bagaimana jika tidak dilakukan perbandingan dengan daerah lain yang memiliki latar belakang sosial budaya dan ekonomi yang berbeda? Tulisan ini bertujuan untuk memahami lebih mendalam kualitas OAP dengan menggunakan pendekatan yang berfokus pada OAP atau people-centered. Pengumpulan data dilakukan melalui wawancara mendalam dan diskusi terpumpun serta observasi lapangan. Hasil kajian menunjukkan bahwa kualitas sumber daya manusia OAP tidak terlepas dari persepsi mereka terkait dengan kesejahteraan. Kecukupan dalam memenuhi kebutuhan dasar dan dapat melakukan aktivitas rutin dengan baik merupakan gambaran penilaian OAP terhadap kesejahteraan dan kemudian mempengaruhi motivasi untuk mendapatkan pendidikan tinggi. Peningkatan kualitas pendidikan dan kesehatan banyak ditemui di daerah yang sudah terpapar pembangunan infrastruktur dan juga hidup berdampingan dengan migran dari luar Papua. Tulisan ini  menyimpulkan bahwa penting memahami kualitas SDM berdasarkan karakter wilayah dan budaya setempat. Sehingga upaya meningkatkan kualitas SDM tidak semata bersifat instruksi tetapi lebih partisipatif dan kolaboratif. Tulisan ini memberikan gambaran yang signifikan terkait dengan keadilan dalam menilai kondisi kualitas SDM kelompok masyarakat tertentu.
Conspiracy Theories and Modern Disjuncture Amidst COVID-19 in Indonesia
Authors: Nadzir Ibnu
Published: September 2022

Amidst the global outbreak of COVID-19 in Indonesia, the government has been under the spotlight for not being able to formulate a proper response. Aside from the malfunctioning bureaucracy, the low compliance among Indonesian citizen toward public health advice complicates the impact of COVID-19 in Indonesia. One factor that contributes to the attitude of society is the spread of false information and conspiracy theories associated to the virus itself. How do we explain the spread of conspiracy theories propagation under the threat of COVID-19 in Indonesia? The article argues that the spread of conspiracy theories amidst the pandemic reflects the on-going contestation of political legitimacy between state and society in Indonesia. To elaborate this point, the article elucidates the three critical junctures that buttressed the propagation of conspiracy theories. First, conspiracy theory was utilized as a foundation of authoritarian regime of Soeharto, and later became an institutionalized tool to maintain its power. Second, the entanglement between democratic ecosystem and proliferation of social media after Reformasi has enabled society to appropriate conspiracy theories as a form of resistance and skepticism toward government. Third, the tension between state and society in regards to the authority manifested on the contention on COVID-19 management in Indonesia. The government have been trying to maintain the legitimacy by being secretive on COVID-19 information. At the same time, some elements of society responded to the secretive government with propagation conspiracy theories that also justify public disobedience toward health protocols. These combinations have further exacerbated the impact of COVID-19 in Indonesia.
Masculine Domination during Epidemic of Covid-19 in The Sotang’s Village, Tuban: The Perspective of Pierre Bordieu
Authors: Sya'adah Faridlatus , Febriyanti Fitri
Published: September 2022

This article aims to discuss the form of masculine domination in the role of women in facing the impact of the Covid-19 pandemic, especially in the social, economic, and cultural fields found in Sotang’s Village, Tambakboyo District, Tuban Regency. Type of this research is descriptive qualitative. The research object was a housewife with a new profession as an onion cutter in the lower middle class environment. The housewife comes from a family affected by Covid-19. Data obtained through observation and semi-structured interviews. The thinking framework used is Pierre Bordieu's perspective on the masculine domination. The masculine domination that was found in the social practices of the Sotang’s Village during the Covid-19 pandemic included: (1) women and onion cutting jobs during the Covid-19 outbreak; (2) female onion cutters as mothers and teachers; (3) space contestation for women onion cutters; (4) poverty and women. The role of women in increasing economic capital cannot be exchanged for symbolic capital. The form of masculine domination followed by symbolic violence as a result of the persecution of women from the lower middle class in the  Sotang’s Village during the Covid-19 pandemic has become part of the strengthening of androcentric culture.
Mengembangkan Tatanan Baru Pascapandemi: Pendekatan Deradikalisasi dan Reproduksi Tafsir
Authors: Rohman Saifur
Published: September 2022

Sejak kasus Covid-19 terkonfirmasi pertama kali pada 2 Maret 2020 hingga sekarang (Februari 2020), kini mencapai lebih dari satu juta kasus di Indonesia. Akumulasi kasus di seluruh dunia telah mencapai 8 juta. Deretan angka dari 0 kasus hingga 31 ribu kasus di Indonesia telah memberikan sketsa penting tentang “bagaimana cara menghadapi” dan bagaimana merancang sebuah norma baru pada masa depan. Sebaliknya rancangan kehidupan yang baru tersebut tidak selalu dianggap selaras dengan “cara menjalankan keyakinan” selama ini. Paradoks ini akan diteliti di dalam praktik kehidupan sosial selama Maret-Juni 2020. Objek kajian adalah kasus-kasus penolakan yang dilakukan oleh masyarakat terhadap kebijakan Pemerintah yang menerapkan pembatasan sosial berskala besar karena dianggap menghalangi praktgik relijius masyarakat. Kasus-kasus itu diperoleh dari unggahan media sosial dan dinilai sebagai representatif. Pemecahan dalam bentuk dialog hanya makin menunjukkan kekuasaan di satu pihak dan kelemahan di pihak lain. Dengan begitu, direkomendasikan untuk merancang sebuah konstruksi tafsir yang persuasif, negosiatif, dan praktik deradikaliasi sebagai upaya menyakinkan sehingga bisa diterima oleh pihah-pihak yang dituju.
Longitudinal Assessment of Bile Duct Loss in Primary Biliary Cholangitis
Authors: Hercun Julian , Noureddin Mazen , Noureddin Nabil , Eccleston Jason , Woolridge Daniel , Liang T. Jake , Tana Michele , Kleiner David E. , Rodriguez Gracia Viana , Koh Christopher , Hoofnagle Jay H. , Heller Theo
Published: September 2022

INTRODUCTION:

Bile duct involvement is a key finding of primary biliary cholangitis (PBC). The aim of this study was to evaluate baseline ductopenia and disease progression.

METHODS:

Retrospective longitudinal histological follow-up of treatment-naive patients with PBC.

RESULTS:

Eighty-three patients were included, with ductopenia correlated to fibrosis stage at baseline. The cumulative incidence of severe ductopenia remained stable after 5 years, whereas fibrosis continually increased over time. Baseline AST-to-Platelet Ratio Index and elevated alkaline phosphatase >2 times the normal with abnormal bilirubin were associated with ductopenia progression.

DISCUSSION:

Bile duct injury does not seem to follow the same course as fibrosis in PBC.
The Infidelity Scale: Psychometric properties and gender invariance among Portuguese adults
Authors:   Instituto Universitário Egas Moniz, Caparica, Portugal, Almeida Telma Catarina ,   CiiEM – Centro de Investigação Interdisciplinar Egas Moniz, Caparica, Portugal,   LabPSI – Laboratório de Psicologia Egas Moniz, Caparica, Portugal, Fernandes Filipa ,   Instituto Universitário Egas Moniz, Caparica, Portugal
Published: September 2022

Introduction: Infidelity is a breach of trust or a crossing of the boundaries of the primary relationship and it influences intimate relationships. It can be categorised as either sexual or emotional infidelity. In Portugal, there have been few studies on this subject using suitable instruments. Objective: This study aimed to analyse the factor structure, psychometric properties, and gender invariance of the Infidelity Scale (IS) in Portuguese adults. Method: The sample comprised 660 Portuguese adults (455 women and 205 men) between 18 and 79 years of age who had been unfaithful in their relationships. Results: The confirmatory analysis showed a structure with two factors (sexual and emotional infidelity), and good values for convergent and discriminant validity were found. The results displayed a satisfactory model fit and the non-invariance of the factor structure between women and men. Conclusion: This is the first Portuguese version of the IS, an instrument for the study of intimate relationships which contributes to the development of multicultural research.
Researching the prospects for change that COVID disruption has brought to high stakes testing and accountability systems
Authors: Moss Gemma
Published: September 2022

This paper explores the disruption that COVID has brought to the normal functioning of performance-based accountability systems and asks whether this has created new possibilities for those organising against the use of high stakes testing in education. Drawing on a sequence of research projects exploring primary schools’ responses to the pandemic in England during 2020-21, this article considers the ways in which the pandemic creates new conditions for dismantling high stakes testing and accountability regimes, and the role of research in making the case for change.
Analisis Spasial Area Genangan Banjir Rob Setelah Pembangunan Tanggul di Kabupaten Pekalongan, Jawa Tengah
Authors: El-Fath Daffa Dinan Ihsani , Atmodjo Warsito , Helmi Muhammad , Widada Sugeng , Rochaddi Baskoro
Published: September 2022

Banjir rob merupakan bencana yang banyak terjadi di daerah pesisir Pulau Jawa, salah satunya Kabupaten Pekalongan yang diakibatkan karena adanya kenaikan muka laut dan penurunan muka tanah. Banjir rob di Kabupaten Pekalongan ini sudah dilakukan mitigasi yaitu dengan membangun tanggul setinggi 3 meter. Adanya kenaikan muka laut dan penurunan muka tanah menyebabkan tanggul ini akan tenggelam. Tujuan dari penelitian ini adalah melakukan analisa spasial area genangan rob tahun 2020 sampai 2030 setelah dibangunnya tanggul, dan memprediksi tanggul dapat menahan genangan rob sampai genangan tersebut melewati batas ketinggian dari tanggul dalam tahun 2020 sampai 2030.  Data pengukuran ketinggian tanggul didapatkan menggunakan alat ukur meteran. Metode pengolahan data yang digunakan adalah metode least square untuk pengolahan pasang surut, metode regresi linier untuk pengolahan kenaikan muka air laut, metode InSAR untuk pengolahan data topografi muka tanah, metode DInSAR untuk pengolahan penurunan muka tanah, dan metode analisis spasial untuk mengetahui luas genangan banjir rob. Hasil data pengukuran ketinggian tanggul memiliki nilai antara 2,6 sampai 2,9 meter dengan nilai error sebesar 7,46%. Hasil pengolahan pasang surut didapatkan nilai HHWL sebesar 203,36 cm dan MSL sebesar 161,25 cm dengan tipe pasang surut condong harian ganda. Nilai kenaikan muka laut sebesar 6,81 mm/tahun. Nilai topografi muka tanah sebesar 0 sampai 5,96 meter. Nilai penurunan muka tanah sebesar 25,13 sampai 40,49 cm/tahun. Luas genangan banjir rob tahun 2020 sebesar 1081,93 hektar dan diprediksi semakin meluas menjadi 7389,47 hektar tahun 2030 dan tanggul diprediksi seluruhnya tenggelam.
PERBEDAAN FAKTOR-FAKTOR KEJADIAN DIARE PADA BALITA DI DESA ODF (OPEN DEFECATION FREE) DAN NON ODF DI WILAYAH KERJA PUSKESMAS SAPE KABUPATEN BIMA M
Authors: Muhlisan Muhlisan , Joko Tri , Yunita Dewanti Nikie Astorina
Published: September 2022

Kejadian diare pada balita masih tergolong tinggi di Desa ODF dan non ODF di Kecamatan Sape. Dalam kurun waktu dua tahun terakhir mengalami peningkatan dari 47,87% menjadi 63,98%. Penelitian ini bertujuan untuk mengetahui perbedaan kondisi kejadian diare pada balita di Desa ODF dan non ODF. Penelitian ini menggunakan pendekatan cross sectional. Populasi dalam penelitian ini seluruh balita rentang usia 1-5 tahun yang ada selama tahun 2019, sampel dalam penelitian ini sebanyak 57 balita yang menderita diare 3 bulan terakhir di Desa ODF maupun di Desa non ODF. Hasil penelitian menunjukkan bahwa responden memiliki rata-rata usia 32 tahun, dengan mayoritas tamatan SMA 48,2%, dan 95,6% lainnya merupakan ibu rumah tangga. Hasil uji statistik menunjukkan bahwa terdapat perbedaan  antara jenis jamban leher angsa dan jamban cemplung dengan kejadian diare pada balita di Desa ODF dan non ODF (p= 0,038), praktek cuci tangan pakai sabun tidak ada perbedaan dengan kejadian diare pada balita (p=0,844), pengolahan air minum tidak memiliki perbedaan terhadap kejadian diare pada balita di desa ODF maupun Non ODF (p=0,239), hasil pemeriksaan bakteriologis  tidak memiliki perbedaan terhadap kejadian diare pada balita di desa ODF maupun Non ODF (p= 0,246), jenis sumber air tidak memiliki perbedaan  terjadinya diare pada balita di desa ODF maupun non ODF (p=0,236). Kesimpulan ada perbedaan kondisi di desa ODF dan Non ODFpada keluarga yang memiliki balita diare di wilayah Puskesmas Sape pada penggunaan jamban, sedangkan sumber air minum, pengolahan air minum, perilaku cuci tangan pakai sabun dan kualitas bakteriologis tidak ada perbedaan kondisi secara signifikan.
MEDIA EDUKASI PROMOSI KESEHATAN MELALUI FILM DALAM MENUMBUHKAN PENGETAHUAN, SIKAP DAN PERILAKU KESEHATAN REPRODUKSI PADA REMAJA
Authors: Husodo Besar Tirto , Handayani Novia , Aisyiyah Purnamawati Ulfa Velia
Published: September 2022

One way to provide adolescent reproductive health education is through film media. Films are a collection of events that occur in unique human life and are poured into the screen. Signs produced by humans are used as visuals that can be seen from various perspectives and provide a separate message for each individual. “Dua Garis Biru” is a form of reproductive and sexual health promotion in form of movie for teenager, which is an attractive ways for teenager to understand the information about reproductive and sexual health. This study aims to explain how the understanding of reproductive health content delivered through the movie "Dua Garis Biru" to teenager at Junior High School X Semarang City. This research was conducted using quantitative descriptive method and cross sectional design. The population in this research were 567 students from 8th and 9th grade of 2020/2021 academic year who attended Junior High School  X Semarang City. The total of sample in this study is 85 respondents who were determined through the calculation of the Slovin formula. The results showed that the knowledge and attitudes of respondents who are already good after receiving information on adolescent reproductive health content through “Dua Garis Biru” were 58.8% and 68.2%. “Dua Garis Biru” can be used as a media in providing adolescent reproductive health education in schools.
GAMBARAN PERILAKU SEKSUAL PRANIKAH PADA MAHASISWA ALUMNI PESANTREN DI PROVINSI DKI JAKARTA
Authors: Nuhaa Zulfaa Nurin , Kusumawati Aditya , Musthofa Syamsulhuda Budi
Published: September 2022

Premarital sexual behavior among adolescents is an increasing problem, especially in big cities such as Jakarta. This problem also occurs to many college students in the late adolescence stage. Premarital sexual behavior can negatively impact health and non-health aspects. This problem encouraged the parents to send their children to Islamic boarding school, hoping a good character could be developed, averting such behavior. The data on this qualitative descriptive research was collected by an indepth interview with eight research subjects with the snowball sampling method. The validity test was done by nine triangulation subjects who are close friends of research subjects at this moment and when they were on Islamic boarding school, while the reliability test was done by data auditing. In this study, the research subjects were labeled as a delinquent by their parents, thus forced to go to modern Islamic boarding school hoping a good character as the earlier alumni while having excellent general knowledge. Still, that label was planted in themselves, and their character was not as expected, which made them feel accustomed doing a deviant behavior such as premarital sex.
IMPLEMENTASI KEBIJAKAN STANDAR PELAYANAN MINIMAL PENDERITA DIABETES MELLITUS DI PUSKESMAS PANDANARAN KOTA SEMARANG
Authors: Rahmadani Annisa Nurindra , Surjoputro Antono , Budiyanti Rani Tiyas
Published: September 2022

Diabetes mellitus (DM) is the fifth most disease in Semarang, but the achievement of Minimum Service Standard (SPM) only reached 50.64% in 2017. The district with the highest morbidity in Semarang is South Semarang which has two health centers. Puskesmas Pandanaran has lower achievement than the other central health in South Semarang, which is 89%. The purpose of this study is to analyze the implementation of SPM for DM in Puskesmas Pandanaran. The research method is qualitative research with in-depth interviews. Research subjects include the head of puskesmas, the program in charge, the program implementer, and the community. The research was conducted in August-October 2020. The results showed that the implementation of SPM services is still constrained at the stage of logging and early detection of DM patients. Unfulfilled performance targets are affected by standard and policy objectives that are difficult to achieve due to differences in the amount of target with the actual population, lack of infrastructure resources and funding sources, there is no Standar Operational Procedure (SOP) in the implementation of SPM for DM patients, and community knowledge factors. The conclusion of this study is variable that affects the performance of SPM are standards and policy objectives, resources, characteristics of implementing organizations and the social environment of the community. Coordination between health services and health centers regarding the use of data as targets for achievement is required, addition and fulfillment of infrastructure and funds, creating SOPs, forming team to record DM patients, and giving education.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN PRAKTIK KONSUMSI TABLET TAMBAH DARAH (TTD) REMAJA PUTRI DI WILAYAH KERJA PUSKESMAS GILINGAN KOTA SURAKARTA
Authors: Rahayuningtyas Devika , Indraswari Ratih , Musthofa Syamsulhuda Budi
Published: September 2022

Adolescents girls’ tend to be riskier of developing anemia than boys because they experience menstruation every month. Based on survey, 4 of 5 students who received blood supplement tablets at school stated that they don’t want to consume it. This research aimed to analyze any factors related to the practice of consuming adolescents girls’ blood supplement tablet in the work area of the Gilingan Health Care Center Surakarta. The method of this research was analytic quantitative with cross sectional design. The population were 542 adolescents girls’ and a sample of 225 adolescents girls’ were selected using simple random sampling. This research used univariate and bivariate analysis (Chi Square). The results of univariate analysis of characteristics respondents were the majority of the respondents were 17 years old (48,0%), education of the respondent’s father is university (56,0%) and also education of the respondent’s mother is university (44,9%), the occupation of respondent’s father is self-employed (30,7%), the occupation of respondent’s mother is housewife (46,2%), with the majority of parents income of Rp. 5.000.000,00 (12,0%). The result of Chi Square test showed that there is a relation between father’s education (p=0,032), parent’s income (p=0,002), attitude (p=0,000), family support (p=0,000), peer support (p=0,000), support from UKS tutor teachers (p=0,001), health workers support (p=0,003), and access to information (p=0,004) with practice of consuming adolescents girls’ blood supplement tablet. Meanwhile, the respondent’s age (p=0,396), father’s occupation (p=1,000), mother’s occupation (p=0,272), mother’s education (p=0,128), knowledge (p=0,850), school support (p=0,210), availability blood supplement tablets in school (p=0,164), and the availability of control cards (p=0,066) had no relation with practice of consuming adolescents girls’ blood supplement tablet.
ANALISIS FAKTOR – FAKTOR YANG BERHUBUNGAN DENGAN USER SATISFACTION TERHADAP SISTEM RUJUKAN ONLINE PADA PESERTA BPJS KESEHATAN DI KOTA SEMARANG
Authors: Ramadhan Hela Ayu , Arso Septo Pawelas , Nandini Nurhasmadiar
Published: September 2022

Sistem rujukan online merupakan inovasi BPJS Kesehatan dalam mendigitalkan sistem rujukan berjenjang. Sistem rujukan online diharapkan dapat meningkatkan kepuasan dan kenyamanan peserta dalam mendapatkan layanan rujukan. Namun belum ada evaluasi dalam pengukuran kepuasan pada sistem rujukan online hingga saat ini, khususnya di Kota Semarang. Penelitian ini bertujuan untuk mengevaluasi pelaksanaan sistem rujukan online dengan menganalisis faktor-faktor yang berhubungan dengan kepuasan peserta BPJS Kesehatan di Kota Semarang. Penelitian ini merupakan penelitian kuantitatif dengan pendekatan cross-sectional yang melibatkan 100 responden yang dipilih dengan teknik accidental sampling. Hasil penelitian menunjukkan bahwa persentase responden yang merasa puas hanya 54%. Hal ini disebabkan oleh masih belum optimalnya efisiensi administrasi dan efektifitas sistem rujukan online dalam mengurangi antrian. Selain itu ada hubungan antara harapan kinerja, harapan upaya, kondisi fasilitasi, kualitas informasi, dan kepuasan pengguna terhadap penerapan sistem rujukan online di BPJS Kesehatan Kota Semarang dengan p-value <0,05. Hasil penelitian menyarankan kepada BPJS Kesehatan untuk menentukan indikator kepuasan peserta terhadap penerapan sistem rujukan online dan mengintegrasikan sistem rujukan online dengan sistem registrasi di fasilitas kesehatan menengah dan tersier di Kota Semarang. Ada hubungan antara harapan kinerja, harapan upaya, kondisi fasilitasi, kualitas informasi, dan kepuasan pengguna terhadap penerapan sistem rujukan online di BPJS Kesehatan Kota Semarang dengan p-value <0,05. Hasil penelitian menyarankan kepada BPJS Kesehatan untuk menentukan indikator kepuasan peserta terhadap penerapan sistem rujukan online dan mengintegrasikan sistem rujukan online dengan sistem registrasi di fasilitas kesehatan menengah dan tersier di Kota Semarang. Ada hubungan antara harapan kinerja, harapan upaya, kondisi fasilitasi, kualitas informasi, dan kepuasan pengguna terhadap penerapan sistem rujukan online di BPJS Kesehatan Kota Semarang dengan p-value <0,05. Hasil penelitian menyarankan kepada BPJS Kesehatan untuk menentukan indikator kepuasan peserta terhadap penerapan sistem rujukan online dan mengintegrasikan sistem rujukan online dengan sistem registrasi di fasilitas kesehatan menengah dan tersier di Kota Semarang.
ANALISIS TINGKAT PENGETAHUAN TERHADAP PERSONAL HYGIENE DALAM PENCEGAHAN COVID-19 DI RW II DESA KEDUSAN KECAMATAN WIROSARI KABUPATEN GROBOGAN
Authors: Amanina Rodhwa Asma' , Nurjazuli Nurjazuli , Setiani Onny
Published: September 2022

Covid-19 terdeteksi pertama kali di Kota Wuhan, Provinsi Hubei China dengan diagnosis awal pneumonia misterius yang  tidak diketahui penyebabnya, pada 31 Desember 2019. Penelitian menunjukkan adanya infeksi coronavirus tipe baru jenis betacoronavirus yang dikenal dengan nama 2019 novel Coronavirus (2019-nCoV).Transmisi virus ini telah dikonfirmasi dapat menular dari manusia ke manusia dan telah menyebar luas di China dan 192 negara termasuk Indonesia. Data dari Dinas Kesehatan Kabupaten Grobogan menyebutkan masyarakat yang terkonfirmasi positif Covid-19 sebanyak 296 orang dan 10 diantaranya merupakan warga Kecamatan Wirosari. Tujuan dari penelitian ini untuk mengetahui hubungan tingkat pengetahuan terhadap personal hygiene dalam pencegahan Covid-19 di RW II Desa Kedusan Kecamatan Wirosari Kabupaten Grobogan. Jenis penelitian yang digunakan dalam penelitian ini adalah kuantitatif yang bersifat analitik dengan menggunakan pendekatan Cross Sectional. Populasi dalam penelitian ini adalah warga RW II Desa Kedusan Kecamatan Wirosari dengan jumlah sampel sebanyak 98 orang yang diambil dengan teknik purposive sampling. Variabel bebas dalam penelitian ini yaitu tingkat pengetahuan, persepsi, sosial ekonomi, sedangkan variabel terikatnya yaitu personal hygiene dalam pencegahan COVID-19. Pengumpulan data penelitian menggunakan kuesioner melalui google form, kemudian dianalisis menggunakan uji Chi square.  Hasil analisis bivariat menunjukkan terdapat hubungan antara tingkat pengetahuan dengan personal hygiene dalam pencegahan covid-19 nilai p-value (0,005) dan terdapat hubungan antara kondisi sosial ekonomi dengan personal hygiene dalam pencegahan covid-19 dengan p-value (0,001) di Desa Kedusan, Kecamatan Wirosari. Kesimpulan penelitian adalah tingkat pengetahuan dan sosial ekonomi sebagai variable yang berhubungan dengan personal hygiene dalam pencegahan covid-19.
ANALISIS KELENGKAPAN PENGISIAN KARTU PENDERITA KUSTA OLEH PETUGAS KUSTA DI KOTA PEKALONGAN
Authors: Rinjani Nivia Cemerlang , Dharminto Dharminto , Agushybana Farid , Mawarni Atik
Published: September 2022

Leprosy is a contagious disease which is a neglected disease or a case that is neglected because it cannot be completely controlled. Based on PMK No.11 of 2019 concerning Leprosy Eradication, recording and reporting is one of the most important elements to obtain an overview and information on activities at all levels of program implementers.The purpose of this study was to describe the completeness of filling out the leprosy patient cards at the Pekalongan City Health Center. The method of this type of qualitative descriptive research by determining the sources using purposive sampling technique totaling 5 leprosy officers and 33 leprosy patient cards. Data collection using in-depth interviews and observations. Data analysis used qualitative analysis with the stages of data collection, data reduction, data presentation, drawing conclusions and verification. Result : overall of the 33 cards, the average completeness of the leprosy card filling out was 75%. The incompleteness of filling out leprosy patient cards is due to the lack of attitude of leprosy officers, the lack of completeness checks by superiors and limited human resources. Based on the results of the research, it is suggested that the Pekalongan City Health Office be able to coordinate the cooperation between leprosy officers in all puskesmas in Pekalongan City to make joint visits in turn so that the household contact and environmental contacts can be filled completely and increase supervision of the completeness of filling out leprosy patients cards.
ANALISIS FAKTOR LINGKUNGAN FISIK DALAM RUANG YANG BERHUBUNGAN DENGAN KEJADIAN TUBERKULOSIS PARU DI NEGARA BERKEMBANG
Authors: Sriratih Eldrajune Agnes , Suhartono Suhartono , Nurjazuli Nurjazuli
Published: September 2022

One of all the contributing factors of Tuberculosis cases is environmental factors. So many cases of Tuberculosis are found in developing countries. Developing countries still have some issues or problems with environmental or living conditions. For example, in Indonesia, which takes the third place in Tuberculosis cases based on the World Health Organization in 2018, there are problems with sanitation and living conditions that are not well in some provinces in Indonesia. Based on those reasons, this review aims to describe what's the factor that influences the incidence of Tuberculosis. Systematic Review used in this research based on the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) guidelines. Articles reviewed took from some international database and national database. For the international database there are 5 databases, those are NCBI (MEDLINE/PubMed), Science Direct, Scopus, Springer Link, JSTOR and for national databases are Portal SINTA and Garuda Rujukan Digital. Based on 11 articles reviewed, 7 factors associated with Tuberculosis cases found, those are overcrowding, structure and material of building, temperature, lighting, dampness, and cooking fuel. Density of occupancy or overcrowding and the presence of ventilation are factors of the physical environment that are often found. Those factors are related to the income level of their population in each country. In developing country income level leads to the fact that people didn’t have so many sources, especially material to build a good building. A bad structure or quality of the building leads to other environmental factors such as overcrowding also the presence and the functions of ventilation associated with temperature, lighting and dampness.