bluuebunny/crossref_metadata_2025 huggingface dataset:
Velocity-model building with enhanced shallow resolution using elastic waveform inversion — An example from onshore Oman
Authors: Pérez Solano Carlos , Plessix René-Édouard
Published: August 2019

Full-waveform inversion is a powerful data-fitting technique that is used for velocity-model building in seismic exploration. The inversion approach exploits the sensitivity of long-offset, wide-aperture, low-frequency data to the P-wave velocity properties in the subsurface. In the geologically complex land context in which different lithologies interleave and create large elastic property contrasts, acoustic waveform inversion is challenged due to the elastic nature of the data. The large elastic property contrasts create mode conversions. At low-to-intermediate frequencies, due to tuning/interference effects, the changes in the amplitudes of the different events affect amplitude and phase of the waveforms. We found that elastic waveform inversion of the long-offset, wide-aperture, low-frequency data leads to better retrieval of the compressional velocity model than the acoustic inversion and it is more stable. To obtain a good resolution in the shallow part of the model in an efficient manner, we have developed a two-stage inversion workflow that combines offset and frequency continuation. We have evaluated the relevance of this workflow with a challenging data set from South Oman.
Switching to Degludec From Other Basal Insulins Is Associated With Reduced Hypoglycemia Rates: A Prospective Study
Authors: Fadini Gian Paolo , Feher Michael , Hansen Troels Krarup , de Valk Harold W , Koefoed Mette Marie , Wolden Michael , Zimmermann Esther , Jendle Johan
Published: August 2019

Context

Observational studies of insulin degludec (degludec) with hypoglycemia events prospectively recorded are lacking.

Objective

To evaluate the safety and effectiveness of degludec in patients with type 1 diabetes (T1D) or type 2 diabetes (T2D) switching from other basal insulins in routine care.

Design

Results From Real-World Clinical Treatment With Tresiba® was a multinational, multicenter, prospective, observational, single-arm study comprising a 4-week baseline period (preswitch basal insulin) and 12-month follow-up (degludec).

Setting

Routine clinical practice.

Patients or Other Participants

Insulin-treated patients (≥18 years) with T1D (n = 556) or T2D (n = 611) with treatment plans to initiate degludec.

Interventions

Switching to degludec from other basal insulins.

Main Outcome Measure

Change from baseline in number of overall hypoglycemic events recorded in patient diaries.

Results

In T1D, the 12-month follow-up/baseline rate ratios (95% CI) of overall [0.80 (0.74 to 0.88)], nonsevere [0.83 (0.76 to 0.91)], severe [0.28 (0.14 to 0.56)], and nocturnal [0.61 (0.50 to 0.73)] hypoglycemia suggested significantly lower hypoglycemia rates with degludec (all Ps < 0.001). At 12 months, HbA1c, fasting plasma glucose (FPG), and basal insulin dosage decreased significantly. Body weight increased, and treatment satisfaction improved significantly. In T2D, the hypoglycemia rate ratios were overall [0.46 (0.38 to 0.56)], nonsevere [0.53 (0.44 to 0.64)], and nocturnal [0.35 (0.20 to 0.62)] (all Ps < 0.001; too few events for analysis of severe hypoglycemia). At 12 months, HbA1c and FPG decreased significantly. Body weight and insulin dosages remained unchanged, and treatment satisfaction was significantly improved.

Conclusions

In a routine clinical care setting, switching to degludec from other basal insulins was associated with significantly lower rates of hypoglycemia, improved glycemic control, and treatment satisfaction in patients with T1D or T2D.
Une société sans pères peut-elle être féministe ?
Authors: Verjus Anne
Published: August 2019

Précis

L'empire des Nairs, publié en 1793, imagine une société dans laquelle mariage et paternité ont été abolis. L'amour et la sexualité y sont libres pour les deux sexes. Les femmes sont payées par l'Etat pour s'occuper des enfants. Les hommes, libérés de toute responsabilité paternelle, placent leur énergie au service de la science ou de la guerre. Lawrence, l'auteur de cette utopie qui connaît de multiples éditions en allemand, anglais et français, se réclame du féminisme. Mais une société qui charge exclusivement les femmes du soin des enfants peut-elle être considérée comme féministe ? Promouvoir l'amour libre, à une époque où l'on ne maîtrise pas la contraception, n'est-il pas une vision androcentrée de l'égalité des sexes ? On répond à ces questions en comparant les propositions de Lawrence avec la législation française et les romans féministes anglais sur le mariage et la paternité dans l'espace transnational de la cause des femmes des années 1790.

The Empire of the Nairs, first published in 1793, imagines a society in which marriage and paternity would be abolished. Love and sexuality would be free for both sexes. Girls and boys would receive the same education. Mothers, not fathers, would give their name to children. Women would be paid by the state for taking care of children, while daughters and sons would inherit from the maternal lineage. Fathers, by contrast, having no familial obligations, would reserve their sexual energy for love, genius, or war. Lawrence, the English author of this utopia, considered himself a feminist. But how can a society that places the entire burden of raising children on women be feminist? Wasn't advocating free love, in a time with no contraception, an androcentric point of view? Only by examining the way French legislators and English feminist novelists during the 1790s thought about marriage and paternity can we answer these questions.
When the Republic Came for the Nuns
Authors: Sachs Miranda
Published: August 2019

During its first decades the Third Republic's relationship with the Catholic Church soured. While the Republic notoriously recast itself as a secular regime through removing clerics from the classroom, laicization also drove the development of public welfare. By examining the case of ouvroirs, charitable ateliers run by female religious orders to train and employ young women, this article explores the consequences of new ideas about welfare for working-class girlhood. In the context of rising anticlericalism, the Republic mobilized labor law and sent labor inspectors to scrutinize the nuns' treatment of their charges. The Republic's efforts to regulate these spaces represent a transformation in its treatment of girlhood, a recognition that girls' care could not be left to the private sphere. Instead, not only was it the Republic's responsibility to protect these girls, but this protection had a larger, societal imperative.

Durant ses premières décennies, les relations entre la Troisième République et l'Eglise catholique se détérioraient. Si l'écartement du clergé des salles de classe est un exemple notoire de la laïcisation républicaine, l'avènement de l'assistance sociale n'en est pas moins un. En examinant le cas des « ouvroirs », ces ateliers dirigés par des religieuses afin de former et employer des jeunes filles, cet article s'intéresse aux conséquences des conceptions nouvelles de l'assistance sociale pour les filles de la classe ouvrière. Alors que l'anticléricalisme devient de plus en plus présent, la République fait appel aux lois sur le travail et demande aux inspecteurs de vérifier le bon fonctionnement des actions entreprises par les religieuses. Cet effort croissant de la République pour réglementer ces locaux marque un refus de laisser le sort des jeunes filles à la sphère privée ainsi qu'une transformation de la politique sur l'enfance. Quand la République accepte la responsabilité de protéger ces filles des ouvroirs, la protection de l'enfance devient un devoir politique.
Ultrasound-derived Biceps Femoris Long Head Fascicle Length: Extrapolation Pitfalls
Authors: FRANCHI MARTINO V. , FITZE DANIEL P. , RAITERI BRENT J. , HAHN DANIEL , SPÖRRI JÖRG
Published: August 2019

Purpose

This study aimed to compare biceps femoris long head (BFlh) fascicle length (Lf) obtained with different ultrasound-based approaches: 1) single ultrasound images and linear Lf extrapolation, 2) single ultrasound images and one of two different trigonometric equations (termed equations A and B), and 3) extended field of view (EFOV) ultrasound images.

Methods

Thirty-seven elite alpine skiers (21.7 ± 2.8 yr) without a previous history of hamstring strain injury were tested. Single ultrasound images were collected with a 5-cm linear transducer from BFlh at 50% femur length and were compared with whole muscle scans acquired by EFOV ultrasound.

Results

The intrasession reliability (intraclass correlation coefficient [ICC3,k]) of Lf measurements was very high for both single ultrasound images (i.e., Lf estimated by linear extrapolation; ICC3,k = 0.96–0.99, SEM = 0.18 cm) and EFOV scans (ICC3,k = 0.91–0.98, SEM = 0.19 cm). Although extrapolation methods showed cases of Lf overestimation and underestimation when compared with EFOV scans, mean Lf measured from EFOV scans (8.07 ± 1.36 cm) was significantly shorter than Lf estimated by trigonometric equations A (9.98 ± 2.12 cm, P < 0.01) and B (8.57 ± 1.59 cm, P = 0.03), but not significantly different from Lf estimated with manual linear extrapolation (8.40 ± 1.68 cm, P = 0.13). Bland–Altman analyses revealed mean differences in Lf obtained from EFOV scans and those estimated from equation A, equation B, and manual linear extrapolation of 1.91 ± 2.1, 0.50 ± 1.0, and 0.33 ± 1.0 cm, respectively.

Conclusions

The typical extrapolation methods used for estimating Lf from single ultrasound images are reliable within the same session, but not accurate for estimating BFlh Lf at rest with a 5-cm field of view. We recommend that EFOV scans are implemented to accurately determine intervention-related Lf changes in BFlh.
Blogging in the Socio-Cultural Sphere
Authors: Корнилова Виктория , Kornilova Victoria
Published: August 2019

The article is devoted to blogging. Blogging used to promote a product or organization on the Internet. It allows you to successfully implement mediavlijanie on users. According to the author, special attention should be paid to issues associated with the creation of the blog. Reveal the types and ways of doing blog, principles and functions of blogging. In the process of scientific research identifies the specifics of blogging in the socio-cultural sphere. Describes the main criteria for evaluating the performance of blogger.
Statistical Method of Processing the Results of Experimental Research of Polycode-Polymodal Text Influence on Audience (Using the Example of Regional Televigion Sports Coverage)
Authors: Никитина Элина , Nikitina Elina
Published: August 2019

This article analyzes the description of the procedure of statistical processing of the obtained experimental data of polycode-polymodal texts influence on audience. As examples of such complicated texts were taken sports coverages aired on television covering the Republic of Bashkortostan. Sports coverages are polycode-polymodal texts as they combine components belonging to different sign systems in one text and this information is percepted by audience with the help of two channels: visual and audial. In our research the audience was represented by the first-year and secondyear students of Ufa State Aviation Technical University. Their task was to estimate 100 television sport coverages using the scale offered. Because of technical reasons 10 sports coverages were analyzed with the usage of STATISTICA Version 6, Statsoft program. We received the following results. The audial perceptual channel is suggested to be leading as audience’s total perceptual estimation was influenced by reporter’s speech quality (presence or absence speech defects) the most.
Suggestive Function of the Proper Names in the Commercial Advertising Texts of the Glossy Magazine «Tatler»
Authors: Селеменева Ольга , Selemeneva Ol'ga
Published: August 2019

Advertising is an example of persuasive communication, at the beginning of the XXI century it becomes the object of linguistic research in the field of speech suggestion. In the article the author analyzes the proper names as a group of the linguistic signs that ensure the functioning of the program of undocumented influence in the consciousness of the subject and aim to persuade him to buy the advertised object. The material of the study is commercial advertising texts from the magazine «Tatler». The choice of this source of the actual material is due to its prototypicity. This international highly artistic glossy magazine, focused on creating a model of the world of luxury and comfort, is an effective advertising medium. The author comes to the conclusion that in the aspect of suggestive linguistics problems the proper names of three groups are especially important for the advertising text: pragmatonyms, anthroponyms and toponyms. The orientation of the magazine «Tatler» for a specific target audience (people with a high level of the material wealth) affects the selection of the pragmatonyms, anthroponyms and toponyms. For example, pragmatonyms-globalisms, symbolic pragmatonyms, calling cosmetic, jewelry, watch brands, etc., allusive names of the persons with a common background of world fame, the names of the countries and cities that are leaders of the fashion and the beauty industry. These groups of names implement suggestive strategies of idealization of the advertised object and imitation of its exclusivity, high quality, participate in the creation of a psychological effect of the trust, form a positive motivation for the purchase.
Comparison of arthroscopic and open reduction of conservatively irreducible dislocated hips of children
Authors: Presch C. , Eberhardt O. , Wirth T. , Fernandez F. F.
Published: August 2019

Purpose

Children with sonographic grade IV hip dysplasia according to Graf and with failed conservative treatment usually need surgical reduction afterwards. Surgical reduction of the hip can lead to severe complications, the occurrence of residual acetabular dysplasia, osteonecrosis, redislocation and other postoperative complications. This paper investigates whether arthroscopic reduction is a promising alternative to open reduction.

Methods

We retrospectively examined 66 patients (78 hips) who were not older than two years at the first time of surgery. Arthroscopic reduction was performed on 17 children (19 hips) and open reduction on 49 children (59 hips). Patient records were used to determine redislocation, postoperative complication and residual dysplasia. Radiographs were used to determine Tönnis classification for osteonecrosis and pathological acetabular (AC) angle for residual dysplasia. We considered data up to a two-year follow-up. Statistical evaluation was performed with binary logistic regression.

Results

After arthroscopic reduction, 6% showed osteonecrosis, compared with 20% with open reduction (p = 0.334). Redislocation was not observed after arthroscopic reduction but for 29% after open reduction (p = 0.005). An improvement of femoral head coverage was achieved with residual dysplasia of 23.5% after arthroscopic reduction, compared with 62% after open reduction (p = 0.002).

Conclusion

The arthroscopic procedure represents a meaningful alternative to the open procedure due to a lower complication rate, a safe setting, a lower rate of residual dysplasia, no observed redislocation and occurrence of osteonecrosis only once in the arthroscopic group of developmental dysplasia of the hip. The arthroscopic procedure should be tested in further studies and in other clinics in order to broaden the empirical base.

Level of Evidence

Level III (retrospective cohort study)
Mid-regional pro-atrial natriuretic peptide as a biomarker of left ventricular systolic dysfunction in patients with sepsis
Authors: Wasyanto Trisulo , Hermawan Guntur
Published: August 2019

BACKGROUND Releasing cytokine pro inflammation in patients with sepsis (tumor necrosis factor-alpha (TNF-α), interleukin-1β (IL-1β) and IL-6) with other factors (mid regional pro atrial natriuretic peptide [MR-proANP] and TNF-α) will cause left ventricular systolic dysfunction (LVSD). This research aimed to prove MR-proANP as a biomarker of LVSD in sepsis, area under the curve (AUC), sensitivity, specificity, cut-off point and probability of MR-proANP and TNF-α as a biomarker of LVSD.

METHODS Non-experimental diagnostic test with cross sectional design and simple random sampling. Variable examined consisted of MR pro ANP, TNF-α and left ventricular ejection fraction (LVEF). LVSD if LVEF was ≤45%. Statistical analysis using 2 × 2 table and receiver operating characteristic curve using SPSS 22 for window.

RESULTS There were examined 71 patients from November 2013 to March 2014 in tertiary ICU of Moewardi Hospital. There were 22 patients with mild sepsis (30.9%), 40 patients with severe sepsis (56.4%) and 9 patients with septic shock (12.7%). The AUC value of MR-proANP level was 0.84 (95% CI 0.73–0.95), p < 0.001. Optimal cut off point was ≥225.95 pmol/l and diagnostic odd ratio (DOR) was 12.11. The AUC value of TNF-α level was 0.73 (95% CI 0.60–0.86), p < 0.002. Optimal cut-off point was ≥7.36 pg/ml and DOR was 5.03. Multivariate analysis was resulted that MR-proANP was the best predictor of LVSD (AUC 0.78), and TNF-α (0.69).

CONCLUSIONS MR-proANP could be used as a biomarker and the best diagnostic predictor of LVSD.
Effects of low glycemic index diet on insulin resistance among obese adolescent with non-alcoholic fatty liver disease: a randomized controlled trial
Authors: Utari Agustini , Maududi Muhammad Saifulhaq , Kusumawati Ninung Rose Diana , Mexitalia Maria
Published: August 2019

BACKGROUND Obesity is strongly correlated with insulin resistance (IR) and nonalcoholic fatty liver disease (NAFLD). Some studies suggest that dietary intake with low glycemic index (GI) may prevent IR and reduce the incidences of NAFLD. This study was aimed to determine the effects of low GI diet on IR among obese adolescents with NAFLD.

METHODS This study was a randomized controlled trial conducted in two JuniorHigh Schools in Semarang, Indonesia. The subjects were 12–14 years obese students with NAFLD, which divided into intervention and control groups according to schools using block random allocation. The intervention group received nutrition education and lunch diet (low energy, low GI, and low fat); meanwhile, the control group only received nutrition education for 12 weeks. The biochemical evaluation included fasting blood glucose (FBG) and insulin levels. IR was assessed using homeostatic model assessment-insulin resistance (HOMA-IR).

RESULTS Thirty-two subjects were enrolled in this study, 16 of which were assigned to the intervention group and the other to the control group. After 12 weeks, the energy and carbohydrate intake reduced in the intervention group (p < 0.05), FBG remained unchanged, and HOMA-IR increased (4.9 [3.7]–7.2 [3.5]) compared to the control group (6.4 [4.9]–5.5 [2.8]) (p < 0.05). Meanwhile, within the control group, there were no significant differences in the energy and carbohydrate intake as well as biochemical variables.

CONCLUSIONS Low GI modification diet alone may not reduce IR in the obeseadolescents with NAFLD.
Anterior cervical corpectomy and fusion in a 7-year-old boy: a case report
Authors: Saekhu Mohamad , Ashari Samsul , Tandian David , Nugroho Setyo Widi
Published: August 2019

Bicycle mishap, a common and ordinary event occurring in children, can have devastating consequences associated with cervical spine injury. Furthermore, either diagnosis or surgical management of cervical spine injury in children is a challenging issue. This research report a challenging case of an anterior cervical corpectomy and fusion with plating in a 7-year-old boy due to cervical spine instability with spinal cord compression after a bicycle mishap. After 20 months of the primary surgery, the titanium-based cervical plate was removed by a second surgery to allow the growth of the cervical spine.
Decreased sensitivity of several anticancer drugs in TMEPAI knockout triple-negative breast cancer cells
Authors: Wardhani Bantari Wisynu Kusuma , Puteri Meidi Utami , Watanabe Yukihide , Louisa Melva , Setiabudy Rianto , Kato Mitsuyasu
Published: August 2019

BACKGROUND Transmembrane prostate androgen-induced protein (TMEPAI) was reported to be highly amplified in the majority of patients with triple-negative breast cancer (TNBC). TMEPAI is related to poorer prognosis, limited treatment options, and prone to drug resistance compared with other proteins. One of the established markers to determine cancer resistance to drugs is the increased expression levels of drug efflux transporters. However, the role of TMEPAI in cancer resistance to drugs has not been elucidated. This study was aimed to investigate whether TMEPAI participates in cancer resistance to drugs by regulating drug efflux transporters.

METHODS TMEPAI knockout (KO) cells were previously developed from a TNBC cell line, Hs578T (wild-type/WT), using a CRISPR-Cas9 system. The expression levels of drug efflux transporters were determined in Hs578T-KO and Hs578-WT by quantitative reverse transcriptase polymerase chain reaction. Cytotoxic concentration 50% (CC50) of several anticancer drugs (doxorubicin, cisplatin, and paclitaxel) were determined in the two cell lines via 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium assay.

RESULTS The results showed that the mRNA expression of P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) was significantly increased in Hs578T-KO compared with that in Hs578T-WT cells. CC50 of several anticancer drugs investigated (doxorubicin, paclitaxel, and cisplatin) in Hs578T-KO cells was higher than that in Hs678-WT.

CONCLUSIONS TMEPAI participated in the regulation of mRNA expression levels in drug efflux transporters (P-gp, BCRP, and multidrug resistance-associated protein 1). Further studies are necessary to confirm whether this finding might be dependent on the development of cancer cell sensitivity to anticancer agents.
Obesity in school-age children
Authors: Wangge Grace
Published: August 2019

[None]
A HISTÓRIA DA EDUCAÇÃO BRASILEIRA SOB O ENFOQUE DA RELAÇÃO PÚBLICO-PRIVADA: LIMITES E POSSIBILIDADES PARA A SUA DEMOCRATIZAÇÃO
Authors: Pires Daniela De Oliveira , Peroni Vera Maria Vidal
Published: August 2019

O estudo analisa os limites e as possibilidades para a democratização do direito à educação por meio da construção da esfera pública no Brasil e os impasses da relação com setor privado a partir dos anos 1930. A metodologia utilizada tem como base as análises bibliográfica, histórica e legislativa. Assim, contextualiza-se a relação público-privada na história da educação ao longo da formação política e social brasileira. Conclui-se que a educação brasileira, historicamente, sofreu as consequências dos períodos de instabilidade política e social.
Endosso de celebridades e human brands no Instagram: estudo de caso da Coleção Fenty Puma by Rihanna
Authors: Vieira de Souza Rosana , Possebon Gabriele
Published: August 2019

O presente estudo tem como objetivo analisar de que forma se dá o endosso de celebridades na relação da cantora Rihanna com a coleção Fenty, da marca Puma, na plataforma Instagram. Para a base teórica da pesquisa, são apresentados autores que estudam sobre endosso de celebridades, human brands e sites de redes sociais. O estudo é baseado em um método qualitativo de pesquisa com o uso de análise de conteúdo (BARDIN, 2016). Ao analisar o caso Puma/Rihanna busca-se entender até que ponto o endosso de celebridade pode ser estendido para o conceito de human brands no contexto dos sites de redes sociais, adicionando desafios para a publicidade e a comunicação de marketing de modo geral.
Entre a Comunicação, a Política e o Espetáculo.
Authors: Panke Luciana , Philippi Ricardo
Published: August 2019

Investigam-se alguns pontos de convergência conceituais entre o tripé “comunicação, política e espetáculo”, revisando autores que perpassam as três áreas, principalmente aqueles que reexaminam concepções da obra Sociedade do Espetáculo, de Guy Debord (1997). São identificados esforços dos teóricos em entender o consumo, a produção e a circulação de imagens públicas, o que emparelha o conceito de espetáculo político com a estética, em especial pelas estratégias políticas midiáticas que se utilizam de afetos e emoções para a legitimação do poder. Embora este trabalho identifique o determinismo de alguns autores, observa-se também que outros pensadores buscam dialogar com o conceito, a fim de interpretar os pressupostos da Sociedade do Espetáculo na área da comunicação política.
A postura inconstitucional do setor de comunicação brasileiro: O caso Empresa Brasil de Comunicação (EBC)
Authors: Rêgo Marília Gabriela Silva , Silva Acsa Roberta Macena da
Published: August 2019

O presente artigo discute sobre as práticas inconstitucionais no sistema de comunicação brasileiro que dificultam a democratização da mídia. O trabalho aborda de maneira mais específica as investidas contra o setor público de comunicação, com ênfase na Empresa Brasil de Comunicação (EBC) que teve seu conselho curador destituído no governo Temer (2016-2018) e que, no primeiro semestre de 2019, na gestão Bolsonaro (PSL), vivenciou a fusão da TV Brasil (emissora pública) com a TV NBR (estatal). A investigação aponta que este último acontecimento contraria o princípio da complementariedade entre os sistemas privado, público e estatal previsto no Artigo 223 da Constituição Federal de 1988.
Deradikalisasi Masjid Inklusi: Upaya Penghapusan Ideologi Radikal di Yogyakarta
Authors: Muryanti Muryanti , Mulyani Tri
Published: August 2019

Radicalization has recently strengthened in Indonesia. The real act makes in burning and killing war. The violence war takes  the results in casualties and damage. This paper talks the process of deradicalization in the cases of phenomenology radicalization in recent years. One of the activities on the issue is to restore the function of the mosque with various activities at 3 important mosques in Yogyakarta. The UIN Sunan Kalijaga Mosque as a Religious Laboratory in the development of da'wah, the Syuhada Mosque as an Educational and economic institution, and the Jogokaryan Mosque as a pesantren in prospering the environment. These 3 findings indicate the potential character of the inclusion mosque. This gave rise to empowerment activities in religious studies and economic education. the activities in the mosque's efforts to reduce radicalization based on religion.Radikalisasi atas nama agama akhir-akhir ini menguat di Indonesia. Wujud nyata dari hal tersebut adalah aksi teror. Hal ini menggunakan kekerasan yang berakibat korban jiwa dan kerusakan. Tulisan ini hendak mengkaji proses deradikalisasi dalam fenomena pada banyak kasus radikalisasi beberapa tahun ini. Salah satu aktivitas pada isu tersebut mengembalikan fungsi masjid dengan berbagai macam kegiatan pada 3 masjid penting di Yogyakarta. Masjid UIN Sunan Kalijaga sebagai Laboratorium Agama dalam pengembangan dakwah, Masjid Syuhada sebagai Lembaga Pendidikan dan ekonomi, dan Masjid Jogokaryan sebagai pesantren dalam memakmurkan lingkungan tersebut. 3 temuan ini menunjukan potensi karakter masjid inklusi. Hal ini memunculkan kegiatan pemberdayaan dalam kajian keagamaan dan Pendidikan ekonomi. Berbagai macam kegiatan dalam aktivitas masjid tersebut merupakan upaya meredam radikalisasi berbasiskan agama.
Platonism about Goodness—Anselm’s Proof in the Monologion
Authors: Brower Jeffrey E.
Published: August 2019

In the opening chapter of the Monologion, Anselm offers an intriguing proof for the existence of a Platonic form of goodness. This proof is extremely interesting, both in itself and for its place in the broader argument for God’s existence that Anselm develops in the Monologion as a whole. Even so, it has yet to receive the scholarly attention that it deserves. My aim in this article is to begin correcting this state of affairs by examining Anslem’s proof in some detail. In particular, I aim to clarify the proof’s structure, motivate and explain its central premises, and begin the larger project of evaluating its overall success as an argument for Platonism about goodness.
Alinhadores CAD/CAM in-office: futuro ou realidade?
Authors: Rodrigues Ernesto Dutra
Published: August 2019

A busca por tratamentos ortodônticos mais estéticos tem aumentado a demanda por alinhadores transparentes. Apesar dessa modalidade de tratamento produzida pelo método digital estar disponível há mais de uma década, apenas recentemente a evolução da tecnologia 3D permitiu aos ortodontistas produzir alinhadores pelo método CAD/CAM dentro de seus próprios consultórios, o que traz vantagens e desvantagens. O objetivo do presente artigo é apresentar e discutir as etapas de produção dos alinhadores, incluindo os métodos de aquisição do modelo digital, planejamento virtual, impressão 3D e estampagem.
Niklas Luhmann’s theory of social system and the reflection on translation system
Authors: Mutlu Sıla
Published: August 2019

This article aims at discussing an important problem of university education from the point of view of translation studies. The relation of translation education and the translation curriculum with social practice, and the counterpart of translation studies departments in the social system, constitute an important problem in the field of translation. It is possible to increase the quality of the translation industry through translation education by identifying the counterparts of translation education and translation theories in practice, and their positions within the translation system. The realisation of this objective is possible by considering translation as a system. Thanks to this approach of considering translation as a system, the positions of the actors within the translation system may be reinterpreted. This article aims at redefining the position of all stakeholders of the translation system within the translation system.

Extended English summary is in the end of Full Text PDF (TURKISH) file.

 

Özet

Bu makale üniversite eğitiminin en önemli sorunlarından birisi olan kuram pratik ilişkisini çeviribilim perspektifinden tartışmayı amaçlamaktadır. Kuram ve uygulama bir sistemin dönüşüm hallerini temsil ederler. Kuramdan pratiğe ve pratikten kurama dönüşle gerçekleşen toplumsal sistemler, kendi bağımsız işleyişlerini ve kalitelerini sürdürme yeteneğini geliştirebilirler. Çeviri eğitiminin ve çeviri müfredatının toplumsal pratikle ilişkisi ve çeviri bölümlerinin toplumsal sistemdeki karşılığı çeviri alanının önemli bir sorunsalıdır. Çeviri eğitimi ve çeviri kuramlarının pratikteki karşılıkları ve çeviri sistemi içindeki konumlarının yeniden belirlenerek, çeviri sektörünün çeviri eğitimi yoluyla kalitesini artırması mümkündür. Bu amacın gerçekleşebilmesi çevirinin bir sistem olarak ele alınmasıyla mümkündür. Çevirinin bir sistem olarak ele alınması sayesinde, çeviri sistemindeki aktörlerin konumları yeniden yorumlanabilir. Bu yazı, Luhmann’ın sistem kuramından yola çıkarak, çeviri sisteminin tüm paydaşlarının çeviri sistemindeki rolünün yeniden belirlenmesini amaçlamaktadır.
Serum level of insulin-like growth factor-I in type 2 diabetic patients: impact of obesity
Authors: Aleidi Shereen M. , Shayeb Eman , Bzour Jameel , Abu-rish Eman Y. , Hudaib Mohammad , Al Alawi Sundus , Bustanji Yasser
Published: August 2019

Background

Insulin-like growth factor-I (IGF-I) is homologous to proinsulin and possesses glucose reducing activity. The association between the level of IGF-I and diabetes has been highlighted. However, this association is controversial due to the influence of different factors including obesity. The aim of the study was to evaluate serum level of IGF-I in type 2 diabetic patients compared to control subjects.

Materials and methods

A cross-sectional study involving 100 participants was conducted. Serum levels of IGF-I were measured using enzyme-linked immunosorbent assay (ELISA) and the fasting plasma glucose (FPG) levels were measured using the glucose oxidase method.

Results

IGF-I levels in the diabetic patients were significantly lower than in non-diabetic control subjects (105.13 ± 6.34 vs. 159.96 ± 9.62 ng/mL, p < 0.0001). Among the diabetic group, there was no significant difference in IGF-I levels between obese diabetic patients and non-obese diabetic patients, p = 0.18. Similarly, among the non-diabetic group, a non-significant difference was found in IGF-I levels between obese non-diabetic and non-obese non-diabetic subjects, p = 0.156. However, among the obese group, obese diabetic patients had significantly lower IGF-I serum levels compared to obese non-diabetic subjects (112.07 ± 7.97 vs. 147.07 ± 13.05 ng/mL, p = 0.02). Furthermore, among the non-obese group, the non-obese diabetic patients had significantly lower IGF-I serum levels compared to the non-obese non-diabetic subjects (91.66 ± 9.93 vs. 171.86 ± 13.86 ng/mL, p < 0.0001). No significant associations were observed between IGF-I level and any of the age, gender, body mass index (BMI), FPG levels, or the duration of diabetes.

Conclusions

Type 2 diabetes mellitus is associated with lower levels of IGF-I regardless to the presence or absence of obesity.
Russland und Deutschland im Schicksal und Schaffen des Schriftstellers Eugen Gagarin
Authors: Galimova Elena Š. , Polikarpov Aleksandr M. , Korin Sabine
Published: August 2019

Little is known about the life and literary creations of Eugen Gagarin. This article deals with the facts known so far and explores archive material to expand and partially correct them. The writer Evgenij Andreevich Gagarin (1905‒1948) was born in the province of Arkhangelʼsk (Archangelʼskaja gubernija) and emigrated to Germany in 1933, where he started writing. Until his tragic accidental death in 1948 he wrote various oeuvres in German and in Russian, including the 1948 novel Vozvraščenie Korneta (‘The Return of the Cornet’), which bears autobiographical features. First published in Russia in 1991, it initiated the acquisition of his works in Russia. This article seeks to contributes to the academic analysis of Gagarin’s Œuvre by systematizing and completing the biographical data on Eugen Gagarin and his family, as well as the information on the publications of Gagarinʼs works.
Brain gene expression in a novel mouse model of postpartum mood disorder
Authors: Humby Trevor , Davies William
Published: August 2019

Background

Steroid sulfatase (STS) cleaves sulfate groups from steroid hormones; its expression/activity increases in late pregnancy and into the postpartum period. STS-deficient human and mouse mothers display elevated psychopathology and abnormal behaviour respectively; in mice, these effects can be partially normalised by antipsychotic (ziprasidone) administration.

Methodology

We compared brain gene expression in new mouse mothers administered the STS inhibitor 667-Coumate, or vehicle; significant changes were followed-up with pathway analysis and quantitative polymerase chain reaction (qPCR). Finally, the effects of combined 667-Coumate and ziprasidone administration on expression of the most robustly differentially-expressed genes were examined.

Results

Surprisingly, no between-group gene expression changes were detected at a False Discovery Rate (FDR)-corrected p<0.1. 1,081 unique expression changes were detected at p<0.05, two top hits were verified by qPCR, and pathway analysis indicated enrichment of genes involved in olfactory transduction. The expression of Stoml3 and Cyp2g1 was unaffected by ziprasidone administration.

Conclusions

Postpartum behavioural abnormalities in STS-deficient mothers are likely to be the culmination of many small gene expression changes. Our data are consistent with the idea that olfactory function is key to maternal behaviour in mice, and suggest that aberrant expression of olfactory system genes may underlie abnormal maternal behaviour in STS-deficient women.
Dynamic Gain Analysis Reveals Encoding Deficiencies in Cortical Neurons That Recover from Hypoxia-Induced Spreading Depolarizations
Authors: Revah Omer , Stoler Ohad , Neef Andreas , Wolf Fred , Fleidervish Ilya A. , Gutnick Michael J.
Published: August 2019

Cortical regions that are damaged by insults, such as ischemia, hypoxia, and trauma, frequently generate spreading depolarization (SD). At the neuronal level, SDs entail complete breakdown of ionic gradients, persisting for seconds to minutes. It is unclear whether these transient events have a more lasting influence on neuronal function. Here, we describe electrophysiological changes in cortical neurons after recovery from hypoxia-induced SD. When examined with standard measures of neuronal excitability several hours after recovery from SD, layer 5 pyramidal neurons in brain slices from mice of either sex appear surprisingly normal. However, we here introduce an additional parameter, dynamic gain, which characterizes the bandwidth of action potential encoding by a neuron, and thereby reflects its potential efficiency in a multineuronal circuit. We find that the ability of neurons that recover from SD to track high-frequency inputs is markedly curtailed; exposure to hypoxia did not have this effect when SD was prevented pharmacologically. Staining for Ankyrin G revealed at least a fourfold decrease in the number of intact axon initial segments in post-SD slices. Since this effect, along with the effect on encoding, was blocked by an inhibitor of the Ca2+-dependent enzyme, calpain, we conclude that both effects were mediated by the SD-induced rise in intracellular Ca2+. Although effects of calpain activation were detected in the axon initial segment, changes in soma-dendritic compartments may also be involved. Whatever the precise molecular mechanism, our findings indicate that in the context of cortical circuit function, effectiveness of neurons that survive SD may be limited.

SIGNIFICANCE STATEMENTSpreading depolarization, which commonly accompanies cortical injury, entails transient massive breakdown of neuronal ionic gradients. The function of cortical neurons that recover from hypoxia-induced spreading depolarization is not obviously abnormal when tested for usual measures of neuronal excitability. However, we now demonstrate that they have a reduced bandwidth, reflecting a significant impairment of their ability to precisely encode high-frequency components of their synaptic input in output spike trains. Thus, neurons that recover from spreading depolarizations are less able to function normally as elements in the multineuronal cortical circuitry. These changes are correlated with activation of the calcium-dependent enzyme, calpain.
Choosing a Thirteenth-Century Motet Tenor: From the Magnus liber organi to Adam de la Halle
Authors: Bradley Catherine A.
Published: August 2019

This article explores trends and motivations in the selection of plainchant and vernacular song quotations as the foundations of thirteenth-century motets. I argue that particular tenor melodies that received only cursory treatment in the liturgical polyphony of the Magnus liber organi were adopted in motets on account of their brevity and simplicity, characteristics that enabled their combination with upper-voice song forms and refrain quotations. Demonstrating a preference for short and simple tenors within the earliest layers of the motet repertoire, I trace the polyphonic heritage of the tenor omnes, whose simple melody enabled its combination with another more obscure plainchant quotation, aptatur, in a unique double tenor motet. I propose that motet creators—while sensitive to the semantic connotations of tenor texts—exploited the musical ability of tenor quotations to be combined with or stand in for other musical quotations. Newly identifying a plainchant tenor source in a motet by Adam de la Halle, I show that Adam's polyphonic motet quotations of his own three-voice polyphonic rondeaux were achieved by the careful selection of motet tenors to replicate the freely conceived lowest voices of these preexisting rondeaux. The article further reveals profound modal and melodic similarities between the quotations chosen as thirteenth-century motet tenors and the newly composed lowest voices of polyphonic rondeaux and English pes motets. It offers new perspectives on the relationship between the “elite” genre of the motet and types of polyphony that are less well attested in written sources, often considered to inhabit a more “popular” realm of musical practice.
Attitude of Postmenopausal Women Toward the Menopause and Hormone Treatment in Enugu, Southeast Nigeria
Authors: Ezeome Ijeoma V , Ezugworie Joseph O , Nwankwo Theophilus O
Published: August 2019

Objectives: Menopause is a naturally occurring event in which there is a failure of a woman’s ovarian function, thus ending her ability to bear children. However, the attitude of women about menopause and its treatment vary in different societies. The present study assessed postmenopausal women’s attitude and knowledge about menopause and hormone treatment (HT) in a private specialist clinic in Enugu, Nigeria. Materials and Methods: This descriptive cross-sectional survey was conducted on 400 consecutively selected women at the gynecologic clinic of a specialist hospital in Enugu through a structured questionnaire. Descriptive statistics were applied to investigate women’s attitudes using SPSS software. The level of significance was estimated by the chi-square test and P<0.05 was considered statistically significant. Results: The mean age of the respondents at menopause was 48.4 (±5.2) years, and their ages ranged between 38 and 52 years. A total of 300 (75%) women had at least primary education. In addition, the hot flush was the most common symptom. Further, 236 (59%) of the respondents obtained their information based on experiences and older women while 64 (16%) of them received such information from books and the internet. Totally, 148 (37%) of women sought treatment in the hospital and 196 (49%) of them had heard of HT mostly from their physician. Even though they were aware that HT relieves hot flushes, they were afraid of the perceived side effects like cancer and heart disease. However, 10.3% remained as the current users. Given adequate information, 37% of the respondents would like to use HT. Conclusions: In general, an increased number of postmenopausal women in Enugu, Nigeria seek relief in the hospital and are becoming aware of HT.
The Political Factors that affect Contemporary Art in the Arab world, Descriptive Analytical Study
Authors: Salameh Mohammad Ahmad. Bani , Rafee Yakup Mohd. , Al Smadi Tamara Adnan.
Published: August 2019

This paper examining the determine the political factors that affect contemporary art in the Arab world. through what the Arabic artworks (study sample) contained ideas, there was internal and external political factors that affect contemporary Arabic art. the researcher will extract these factors by evaluating the findings made in respect to the political factors (internal and external) that influence the selected artworks (sample study). This step also includes the drawn conclusions in respect to the political factors (internal and external) that cause these political situations in the Arab world. The study sample contained seven Arabic contemporary installation artworks from 2010-2015 to determine the political factors that affect contemporary art in the Arab world.  The findings were list combines the external and internal political factors that influence contemporary Arabic art in general because these factors include all the political factors and its comprehensive and appeared in contemporary Arabic artworks.
The Framing of a Problem through Gaming (Mathematics-STEM) Subject Content Areas
Authors: Ph.D. Charletta H. Barringer-Brown,
Published: August 2019

According to Demeter (2015) over the past fourty years, scientists, engineers, philosophers, and psychologists have been concerned with the infinite number of social, economic, and  physical issues that exist and that cannot be dealt with in isolation. As agruged                                                                                                                                                                                                                                                                                                                                                                                                                                                  by Wong, Luo, and Fong  (2019) it has been found through experiments and piloting techniques that the existing traditional methods and knowledge is not suited into coping and addressing the unique and sophisticated situations. In the process of searching and coming up with techniques such the use of Bernoulli’s principle for aerodynamics and aviation, perturbation techniques, and the nonlinear approximation methods, it was discovered that physics, chemistry, and mathematics brings out a limited area of interest and therefore can only offer solutions to problems in narrow perspectives. For example, the aforementioned disciplines majorly concentrated on a particular subject of interest and use limited principles towards solving the identified problem, that is to say, a significant number of assumptions are brought into play in order to help in arriving at the intended destinations. Notably, the techniques applied in solving scientific problems do not regard competing frameworks and this contributed to their limited nature in solving social and physical problems. As suggested by Leaver,Willson, and Torres (2016) it is against this backdrop that, framing of a problem through gaming techniques in subject content areas is being encouraged since it involves competing frameworks and consequently works to reduce the number of assumptions plunged in the process of solving mathematical problem. Gaming techniques entails the combination of various techniques that can deal with adversities, uncertainty, unique, and sophisticated situations in the field of science. Fundamentally, framing of a problem through gaming tricks provides an advantage of combining the social-human with economic, technological, and physical domains. The outcome associated with the gaming technique is scientific improvements and increased applications of the available knowledge and information (Wong, Luo, and Fong, 2019).
FATTY ACID COMPOSITION IN MEDICINAL MUSHROOMS (CRATERELLUS TUBAEFORMIS)
Authors: Dospatliev Lilko , Ivanova Miroslava , Petkova Zhana , Angelova-Romova Maria , Antova Ginka
Published: August 2019

Bulgaria has a very rich fungal flora due to its phytogeographical position. The screening of
chemical content and active substances of mushrooms becomes an important subject not only for Bulgaria but also for all over the world. In the last decade, Analyses on phytochemical and biological activity of fungi have gradually increased as a result of improvement in the number and quality of facilities. In the scope of the present research, medicinal mushrooms; Craterellus tubaeformis was analyzed for fatty acid compositions by GC-FID, tocopherols by HPLC-fluorescence, and Oil content by Soxhlet. The ongoing research will lead to a new generation of foods, and will certainly promote their nutritional and medicinal use.
Bullous pemphigoid in 65 years old female: a case report
Authors: Sanjaya I Dewa Made Rendy , Artana Putu , Hari Embun Dini
Published: August 2019

Introduction: Bullous pemphigoid is an autoimmune disorder. The incidence of bullous pemphigoid has increased over time, current understanding regarding treatment and complication is an important issue considering the disease often occur in elderly resulting in high rates of morbidity to the patients. Aim of current case report is to describe the clinical relevance regarding symptom and treatment of bullous pemphigoid.Case presentation: A 65 years old female patient, came with chief complaints of bullae in abdominal region with itching and burning sensation in the ruptured bullae. Over time bullae spread in lower and upper extremity. Patient was admitted for four days with therapy intravenous steroids, oral antihistamine, and potent topical steroids. Patient was discharged from hospital in well condition.Conclusion: Bullous pemphigoid is an inflammatory autoimmune skin disease and usually result in good prognosis with adequate management.Keywords: autoimmune, bullous, pemphigoid, skin, disease.