bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of E-Commerce Use in Consumptive Behavior of Students Madiun State Polytechnic
Authors: Netty Lisdiantini  , Bias Nur Elmira  , Farida Tri Hastuti
Published: November 2024

The development of technology and information is currently very influential in all aspects of life, for example the use of social media is not only used as a means of obtaining information but social media is widely used as a means of doing business call an online shop. The development of technology, there are many online buying and selling sites where in it gathers many online shops into one site that makes it easier for buyers to get the items they want with various promos that attract students to shop on the site. In this study, researchers want to know how the development of E-Commerce affects the consumptive behavior of Madiun State Polytechnic students. The method used in this study is descriptive qualitative method with a sample of 105 Madiun State Polytechnic students by distributing questionnaires. The results show that of the 105 samples taken, it can be seen that the biggest influence on students' consumptive behavior towards E-commerce is due to the promo or discount factor provided by E-commerce sites at the beginning of the month.
Integration of Local Wisdom in the Role of Village Heads as Mediators of Industrial Relations Disputes
Authors: Sarah Magfirah Daud  , Nur Mohamad Kasim  , Weny Almoravid Dungga
Published: November 2024

The integration of local wisdom in the role of village heads as mediators of industrial relations disputes is an effective strategy in rural conflict resolution. Local wisdom, which is a community's traditional knowledge and practices, can be used to understand and resolve complex conflicts. The village head, as a respected figure with traditional knowledge, can serve as an effective mediator in resolving industrial relations disputes. The results show that village heads play an important role as mediators by integrating local wisdom principles such as deliberation, mutual cooperation, and harmony in the mediation process. The custom-based approach proved effective in reaching an agreement that was acceptable to both parties and maintaining social harmony in the village. However, challenges arise when dealing with large companies or disputes involving formal legal aspects. This research provides new insights into the potential integration of local wisdom in the resolution of industrial relations disputes at the village level, as well as the implications for the development of a more contextualized alternative dispute resolution system in Indonesia. The analysis will discuss how the integration of local wisdom in the role of the village head can improve the effectiveness of conflict resolution in rural areas.
Digital Transformation and the Role of Digital Platforms in Enhancing Organizational Performance
Authors: Jassim Asst. lecturer Karam Muzaffar
Published: November 2024

Modern technology, with its digital platforms, has become an integral part of contemporary life, providing significant opportunities to harness this revolution optimally for the benefit of individuals and societies. Institutions have played a substantial role in investing in this digital revolution by increasing communication spaces with the community, strengthening relationships with their clients, and focusing on guidance, awareness, reputation enhancement, crisis management, and digital marketing, among other gains achieved through digital platforms. These platforms have also created unprecedented opportunities for workers, companies, and society, unleashing innovation on a global scale. However, at the same time, they pose serious threats to decent work and fair competition. Therefore, this research paper aims to shed light on the role of digital platforms in improving institutional performance, in addition to the challenges they face.
Observing the proliferation of Salmonella sp. in Karnaphuli River: Catastrophic for the Riverbank dwellers
Authors: Alam Md. Wahidul , Khandakar Md. Jahin , Mondal Md. Atiqul Islam , Jahan Most. Israt , Rahman Md. Mosfiqur , Aktar Fowzia
Published: November 2024

The quality of Karnaphuli River water has an important role in human infection and disease sheltered near Karnaphuli River along with the people of Chittagong. The once-powerful Karnaphuli River is severely contaminated, which could lead to the spread of bacterial infections. However, there is very little information available regarding the diversity of bacterial pathogens in Karnaphuli, particularly in the estuary area. The present study was conducted to systematically examine the prevalence of indicator and pathogenic microorganism Salmonella sp. in water and sediment samples along with their relationship with some physiochemical parameters like pH, salinity, DO, temperature, etc. during September 2021. A total of 6 water samples from 6 different stations were taken and samples were examined by the pour plate culture method along with chemical and biological tests for detection of Salmonella sp. This study showed that all water and sediment samples were positive for Salmonella sp. There were significant differences between Station no. 2, referred to as Firingee Bazar, and the 6th station, known as Soltgola. The present research shows that pollution indicators like DO, salinity and the amount of cells of bacteria prevail in the unhygienic and polluted situation of the river which is a clear picture of uncontrolled hazardous activity.
TRILHAS E TEMAS DA DISCIPLINA FILOSOFIA DA EDUCAÇÃO
Authors: Betânia Barbosa Albuquerque Maria
Published: November 2024

Este texto é parte integrante de minha tese de doutorado que visou reconstruir, historicamente, a trajetória da disciplina Filosofia da Educação entre as décadas de 40 a 80 no curso de Pedagogia da Pontifícia Universidade Católica de São Paulo (PUC/SP), considerando os temas que selecionou ou silenciou nos seus programas de ensino, os seus atores e sua produção teórica. Além disso, a tese fez uma incursão na década de 90 objetivando verificar a situação dessa disciplina a partir da pós-graduação, enfocando basicamente o programa de pós-graduação em Filosofia da Educação da PUC/SP, os debates ocorridos no Grupo de Trabalho (GT) em Filosofia da Educação da Associação Nacional de Pós-Graduação e Pesquisa em Educação (ANPEd), das suas pesquisas, eventos e veículos de divulgação. Teoricamente a investigação apoiou-se nos estudos históricos e sociológicos que possibilitam compreender o itinerário das disciplinas, tais como os de André Chervel (1990), Ivor Goodson (1995), Tomaz Popckewitz (1994) e outros.
O PROCESSO DE PRIVATIZAÇÃO DA EDUCAÇÃO SUPERIOR: UM ESTUDO SOBRE O CASO DA UNAMA
Authors: Lúcia Gomes Figueira de Melo Maria , Agrassar Morais Ingrid
Published: November 2024

A agudização da dinâmica do capital no Brasil esculpiu-se com um impulso mais evidente a partir do governo Fernando Henrique Cardoso, porém, identificando as raízes desse processo na conjuntura nacional, percebemos que essa nova forma de organização capitalista, a Macro ordem Neoliberal, remonta-se, ainda, aos primórdios da gestão de Fernando Collor de Mello, responsável pela efetiva abertura da economia nacional ao mercado mundial. Assim, tornamo-nos presas fáceis diante das novas exigências impostas pelo movimento de Globalização do sistema capitalista.
Narratives of Technology and Livelihood Education Teachers in the Use of Authentic Assessment
Authors: Rosal Hanna Claire O.
Published: November 2024

The study aimed to explore the narratives of teachers in the Philippine educational context. It focused on understanding the strategies implemented by teachers, the responses of students to strategy applied, the difficulties encountered by teachers, and how students responded to authentic assessment execution difficulties. By examining these elements through a phenomenological research design, this research interviewed 13 Junior High School teachers from the Division of Cabuyao. In order to select the right informants and participants for the study, the used of Criterion Sampling Method was utilized. This method is a subtype of Purposive Sampling Method used in research to select individuals based on specific predetermined criteria or characteristics. After gathering the data from the participants, a thematic analysis was done to ensure a comprehensive analysis. The inquiry sought to provide an in-depth analysis of the current state and challenges of authentic assessment in schools in Cabuyao, Laguna, Philippines. The findings revealed that teachers employed a variety of authentic assessment strategies aimed at fostering deeper learning and critical thinking skills among students. These strategies included performance-based assessments, project-based learning, and real-world problem-solving tasks. Students generally responded positively to these methods, showing increased engagement and improved learning outcomes. However, the study also highlighted significant challenges faced by teachers, such as limited resources, large class sizes, and a lack of professional development opportunities. There were also issues expressed in terms of curriculum alignment and support.  These difficulties posed hindrances in the effective implementation of authentic assessments. While authentic assessment strategies offered the potential in enhancing student learning, their successful implementation requires addressing the systemic and individual challenges faced by educators. There is a need for increased support in terms of resources, training, and institutional policies to fully realize the benefits of authentic assessment. The findings underscore the importance of a supportive educational environment that empowers teachers to innovate and apply effective assessment methods that cater to the diverse needs of students.
Occurrence of Malaria Parasitaemia among Pregnant Women attending Selected Hospitals in Akure, Southwest, Nigeria
Authors: Akinladejo A. C. , Omoya F. O. , Ajayi K. O.
Published: November 2024

Malaria, a serious and potentially fatal disease caused by Plasmodium parasites, poses a major public health challenge, pregnant women, their unborn children and children under the age of five are among the most vulnerable groups. This study therefore aimed to determine the effects of blood group, genotype and maternal demographic on malaria parasitemia among pregnant women visiting selected hospitals in Akure, Ondo State, Southwest Nigeria. Blood samples were collected and were all analyzed to determine the blood group using the ABO anti sera method and genotype was determined using electrophoresis method. Malaria parasite load was carried out using microscopy (giemsa staining technique) method. The overall incidence of malaria among the outpatient pregnant women is 66.80% (127/190) among which 63.70% (121/190), 2.10% (4/190) and 1.10% (2/190) had mild, moderate and severe parasitaemia levels respectively compared with the control with malaria incidence of 7.30% (3/41). There is no significant (p<0.05) difference in the malaria incidence among different blood groups and genotypes. The parasitaemia loads of those with genotype AS (984.06±504.36 per µL of blood) was significantly (F = 8.039; p – value = 0.005) higher than AA (158.77±11.39 per µL of blood). The high prevalence of malaria among pregnant women underscores the persistent public health challenge in this area.
O impacto da reabilitação fonoaudiológica em crianças com dificuldades de aprendizagem
Authors: Moura Stefanny Loren Silva Soares , Alves Francisca Laura Ferreira Sousa
Published: November 2024

Introdução: As dificuldades de aprendizagem impactam o desenvolvimento cognitivo da criança, uma vez que dificulta nos processos de ensino e aprendizagem, bem como na apreensão de conhecimentos, habilidades e competências necessárias para sua vida adulta. Após a pandemia da civid-19 essas dificuldades potencializaram, haja vista as determinações de isolamento social e lockdown, o que contribuiu para disseminação do ensino híbrido e/ou remoto, o que ocasionou déficits pertinentes à aprendizagem no Brasil. Sob esta lógica, é imprescindível a presença de profissionais capacitados em promover um conjunto de ações e estratégias que possibilitem minimizar os efeitos dos atrasos e dificuldades de aprendizagem em crianças. Objetivo: anlisar a importância do profissional de Fonoaudiologia, haja vista que este pode ajudar a criança a desenvolver fala, linguagem e comunicação, o que irá consequentemente, refletir no seu processo de aprendizagem. A partir desta conjuntura, a pesquisa terá como objetivo avaliar os impactos da reabilitação fonoaudiológica em crianças com dificuldade de aprendizagem. Metodologia: Para tanto, a pesquisa trata-se de um estudo de revisão bibliográfica, com abordagem qualitativa, no qual contempla estudos e pesquisas disponibilizadas nas bases de dados daPubMed, MedLine e Lilacs, publicados entre os anos de 2019 a 2024. Resultados: Foi realizada uma análise crítica e comparativa dos 9 artigos selecionados. Os artigos incluídos evidenciaram que a reabilitação não apenas facilita o desenvolvimento da linguagem, mas também contribui para a melhoria a aprendizagem no geral. Conclusão: A atuação fonoaudiológica vai além do tratamento da fala e da linguagem; é um componente essencial no apoio ao desenvolvimento educacional e social, assegurando que crianças com dificuldades de aprendizagem possam alcançar seu pleno potencial e uma integração mais eficiente na sociedade.
Effectiveness of Bufei Formula and Bufei Yishen Formula as Adjuvant Treatment for Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis
Authors: Han Ying , Yang Dong , Zhao Yan
Published: November 2024

Introduction: Chronic obstructive pulmonary disease (COPD) is a prevalent condition worldwide, and standardized targeted treatments can effectively control its symptoms. However, the efficacy of the Bufei Formula or its modified versions as an adjuvant treatment for preventing COPD exacerbations has not been well established.
Methods: To evaluate the effectiveness of the Bufei and modified Bufei formulas, a systematic review followed by a meta-analysis was conducted. In September 2024, four databases were searched for randomized controlled trials investigating the use of the Bufei Formula and its variations in the treatment of COPD.
Results: Four studies were included in this meta-analysis: one on the Bufei Formula and three on the Bufei Yishen Formula, encompassing a total of 775 patients. The Bufei and Bufei Yishen formulas demonstrated effectiveness in preventing COPD exacerbations, with mean differences (MD) of -0.6 times/person-year (95% CI: -0.68 to -0.52, p < 0.001) and -0.39 (95% CI: -0.47 to -0.32, p < 0.001; I² = 0%), respectively. The combined effect of both formulas in reducing exacerbations was -0.45 (95% CI: -0.60 to -0.31, p < 0.001; I² = 77%). For reducing dyspnea as measured by the modified Medical Research Council dyspnea scale, the Bufei and Bufei Yishen formulas showed mean differences of -0.39 points (95% CI: -0.62 to -0.16, p < 0.001) and -0.46 points (95% CI: -0.67 to -0.26, p < 0.001; I² = 48%), respectively. Additionally, two studies evaluated the Bufei Yishen Formula's effectiveness in improving the 6-minute walking distance, showing a mean difference of 37.0 meters (95% CI: 21.1 to 52.9, p < 0.001; I² = 0%).
Conclusion: Bufei and Bufei Yishen formulas are effective adjuvant treatments for COPD.
Apremilast: a possible alternative to local treatment of Beceht's disease
Authors: Murcia Lourdes
Published: November 2024

This letter aims to raise awareness about Behcet's disease (BD) and its impact, particularly in
Honduras. BD is a chronic inflammatory disease that affects different organs. It is recurrent and of
unknown origin. It is characterized by neurological, ocular, vascular, gastrointestinal, and
mucocutaneous alterations that could be fatal1. Among the mucocutaneous manifestations, we can
mention oral ulcers, also known as thrush, which are usually painful and harm the quality of life of
people who suffer from them2. These mouth ulcers begin as lesions of oral mucosa, gums, tongue,
or lips. They are characterized by being rounded and raised and quickly transform into painful
ulcers. The sores heal in one to three weeks, although they reappear3
. The cause of BD is unknown.
It is believed that there could be a genetic predisposition that has been demonstrated by its
association with HLA genes (HLA B51/B5, MICA gene) and other non-HLA genes (1-ICAM gene,
TNF gene, MEFV gene) and also requires other factors such as the participation of microorganisms
such as streptococci, mycobacteria and Helicobacter pylori4
Prevention of cocoa moniliasis using Progressive Web Applications and sensor data in the province of Francisco de Orellana
Authors: Romero Darwin , Oña Pilar , Aguilar Pedro , Chango Wilson
Published: November 2024

Ecuador is an essential cocoa producer recognized for its quality and aroma. Additionally, it holds a prominent
position among the country's traditional export products, making it the third-largest cocoa-producing country
in the world. However, the cocoa industry faces challenges due to moniliasis, a fungal disease that affects
cocoa trees and causes damage to the fruits, resulting in decreased production. This research aims to prevent
cocoa moniliasis by conducting tests with different algorithms to select the best one for predicting moniliasis
using sensor data in the progressive web application. Various supervised learning algorithms were applied,
including PCA, IPCA, KPCA, Linear Regression, Sci-Kit Learning, and ensemble methods like Bagging and
Boosting. Google's Lighthouse is utilized for artifact validation. It is concluded that the Boosting ensemble
method with a value of 1.0 and 4 estimators is the algorithm that shows a good fit for prediction. In artifact
validation, it yields favorable results with a score of over 90 in various Lighthouse parameters.
Keywords: Moniliasis 1; Progressive Web Application 2; PCA 3; IPCA 4; KPCA 5; Linear Regression 6;
Bagging 7; Boosting 8; Lighthouse 9
Las competencias educativas de la criminología y su ampliación en el campo laboral
Authors: Delgado José Enrique
Published: November 2024

En este artículo se propone una nueva definición de la criminología con base en una revisión epistemológica y etimológica de la disciplina. Tras este procedimiento, los objetivos del área y sus alcances como ciencia se reestructuran para considerar sus competencias educativas declarativas, procedimentales y actitudinales en paralelo a las presentes en el ámbito penal. De esta forma, se pretende ampliar el ámbito profesional de los criminólogos en el mundo empresarial, corporativo, en políticas públicas y las tecnologías de la información y la comunicación. Para lograr tal fin, se realizó un análisis documental junto con el desarrollo y aplicación de un formulario a trece docentes criminólogos de licenciatura para que —desde su pericia y experiencia— ponderen las competencias educativas a la luz de las recientes necesidades profesionales y sociales para, a su vez, modificar el mapa curricular universitario en criminología.
Peshgi Practices in Pakistan: Bridging the Gap with International Labor Standards
Authors: Zaman Fakhar
Published: November 2024

This research paper delves into the pressing issues of child labor and forced labor, focusing on their prevalence and legal frameworks in Pakistan. The paper begins by examining "Peshgi," a prevalent form of child labor in Pakistan, analyzing international standards and Pakistan's legal stance regarding this issue. It further investigates forced labor, exploring global standards and Pakistan's legal framework in combating this violation of human rights. Through a comparative analysis of international standards and Pakistan's legal provisions, the paper aims to assess the efficacy of existing measures in addressing child labor and forced labor. By shedding light on the intricacies of these labor practices and legal responses, this paper contributes to the discourse on combating exploitation and promoting the rights and well-being of vulnerable populations.
COMPARATIVE ANALYSIS OF THE EFFECTIVENESS OF SURGICAL AND CONSERVATIVE TREATMENT OF TWO-PART DISPLACED PROXIMAL HUMERAL FRACTURES IN ELDERLY PATIENTS
Authors:   First Moscow State Medical University named after I.M. Sechenov, Gasparyan D.A. , Repnikov A.S. ,   First Moscow State Medical University named after I.M. Sechenov
Published: November 2024

Purpose. To evaluate the long-term results of treatment of two-part displaced fractures of the proximal humerus in patients over 60 years of age by comparing the effectiveness of surgical treatment using fixing plates and conservative methods. Materials and methods. Between March 2022 and August 2024, a randomized controlled trial was conducted with 22 patients in the Central Hospital of the RCH. Participants were divided into two groups: surgical treatment with the use of fixing plates and non-surgical treatment. The primary outcome measure was the DASH scale, and secondary criteria were the Constant-Murley scales, the Visual Analogue Pain Scale, the 15D and EQ-5D Quality of Life questionnaires, and the Oxford Shoulder Scale. The study was semi-blind, using sealed envelopes and standardized treatments. Results. At 2 years after the start of the study, there were no statistically significant differences in the average DASH score between the groups: 29.1 in the operational group and 28.0 in the non-operational group. The difference was 1.2 points (p = 0.20). Similarly, other measures, including the Constant-Murley scale, VAS of pain, and quality of life assessments, did not demonstrate significant differences in the long term. Conclusions. The study showed that at 2 years there are no statistically significant differences in the results between the operative and conservative treatment of two-part displaced fractures in groups of patients over 60 years of age. These data confirm the lack of benefits of surgery during long-term recovery, emphasizing the importance of an individualized approach when choosing tactics for treating these fractures.
Simulation of infant suction vacuum pressure using WGAN
Authors: Arslan Fatih Furkan , Dinçel Önder
Published: November 2024

In this study, it is aimed to simulate infant suction vacuums by replicating infant suction vacuum pressures with the Wasserstein Generative Adversarial Network (WGAN) model. To understand the physiology of infants' feeding behavior, it is very important to understand the physiology of sucking. One of the most important elements of feeding physiology is the infant suction vacuum. In this context, the infant suction vacuum pressure produced by the WGAN model was successfully simulated. Data preprocessing and hyperparameter optimization were performed to ensure the most accurate simulation of the WGAN model used in the study.
As a result, the low RMSE and high R2 value between the real data and the generated data show that the model works successfully. This method is promising in terms of better understanding the sucking behavior of infants and contributing to solving problems in the field of infant feeding. In the future, infant sucking simulation will be more successful if the model is supported with larger data and other elements of infant sucking physiology such as swallowing and respiration are considered. This kind of simulation will pave the way for new applications in the fields of infant feeding and breastfeeding.
“Quiero Eliminar tu Dolor”. Kinesiología y Fisioterapia en el Paraguay. Su Historia - Evolución - Currículum de Formación - Importancia
Authors: Sotelo Segovia Emiliano
Published: November 2024

Este artículo se centra en la Kinesiología y Fisioterapia en el Paraguay. Tiene por objetivo una descripción cronológica, su evolución e importancia en los hechos relevantes en nuestro país. La investigación fue cualitativa. Se basó en una revisión bibliográfica y en un análisis de documentos recolectados de modo semiestructurados. Se estudiaron varios canales de información: por un lado, los textos y artículos de la Lic. Lelis Noelia Morales Clemotte, la Lic. Loria C. Giménez y el Lic. Marcos Almirón. Por otro lado, el acceso a la información brindada por varias Instituciones Nacionales, como así también publicaciones historiográficas de los siguientes autores: Dra. Mary Monte de López Moreira y Alfredo Boccia Paz. Esta profesión expuesta presenta su valor en el impacto del contexto socio histórico que marca una tendencia de servicio de rehabilitación, dándose su merecido lugar en la salud nacional.
Efecto de la fertilización nitrogenada sobre cobertura de abonos verdes de invierno en maíz (Zea mays L.)
Authors: Ortiz Alfonso Aldo Andrés , Tilleria Laura Diana
Published: November 2024

El maíz es un cultivo tradicional del Paraguay, la fertilización con nitrógeno (N) es una de las prácticas de manejo que más limita el rendimiento. Con el objetivo de evaluar el efecto de diferentes dosis de fertilizante nitrogenado (urea) en la producción de maíz sobre coberturas de mezclas de abonos verdes de invierno, se instaló un experimento el distrito de Encarnación con coordenadas geográficas latitud sur -27°19'50.02" y longitud oeste -55°52'0.01", el diseño experimental fue factorial, se consideró como factor A: dos sistemas de labranza (mescla de abonos verdes de invierno y método convencional de manejo de suelo) y factor B: tres dosis de urea (0, 150 y 300 kg ha-1). Se evaluaron las variables número total de granos por mazorca, peso de mil granos y rendimiento. El número total de granos por mazorca con un valor máximo de 380 granos por mazorca presentó diferencia altamente significativa para el efecto del manejo donde el valor fue de 214 granos/mazorca, mientras que la diferencia
fue no significativa para los efectos de dosis de urea y la interacción. El peso de mil granos y rendimiento presentaron diferencias altamente significativas para los efectos individuales como en la interacción. El mayor rendimiento de grano fue de 3.903 kg ha-1 con la combinación de 300 kg ha-1 de urea sobre suelo con cobertura de abonos verde de invierno. El rendimiento de grano del maíz es relacionado por el número de granos por mazorca y el peso de granos, a su vez el sistema de manejo de suelo influye en la eficiencia de utilización de la urea como fertilizante en el maíz considerando que este es un cultivo parte de los sistemas agrícolas tanto para pequeños, medianos y grandes productores.
El Aporte de la Mediación en los Procesos de la Niñez y Adolescencia en el Juzgado en la Ciudad de Saltos del Guairá – Paraguay
Authors: Acosta Alvarenga Mirian Beatriz
Published: November 2024

El objetivo fundamental de este estudio se centró en mostrar que, frente a los conflictos familiares, la mediación se presenta como una vía extrajudicial de resolución de conflictos. Por medio de ella, se ofrece al grupo familiar la oportunidad de reorganizarse, sin intervención de los tribunales. Con todo esto se procuró determinar el aporte de la mediación en los procesos de la niñez y adolescencia en la Oficina de Mediación de la Circunscripción Judicial de la ciudad de Saltos del Guairá en el periodo 2016-2021 para lo cual se ha estudiado los expedientes ingresados en el Juzgado de la Niñez y Adolescencia. El tipo de investigación fue no experimental, el método utilizado fue el deductivo y la técnica fue la documental directa con un nivel descriptivo. En definitiva, se puede afirmar que remitir estos Juicios a dicha Oficina, a fin de la búsqueda de un acuerdo es una de las mejores alternativas de dirimir conflictos, buscando así una justicia rápida, barata, eficaz y segura para las partes.
Metodología de implementación del Costeo Basado en Actividades para Micros, Pequeñas y Medianas Empresas en Paraguay. Año 2020
Authors: Alegre Miguel
Published: November 2024

En Paraguay, particularmente, las Micro pequeñas y medianas empresas (Mipymes) tienen dificultades para la confección y diseño de sus sistemas de costos, además que el Costo Basado en Actividades (CBA) es poco conocido en nuestro país, y principalmente por el tipo de empresas mencionadas. El objetivo general de este trabajo fue diseñar la Metodología de Implementación del Costo Basado en Actividades para Micros, Pequeñas y Medianas Empresas en Paraguay, año 2020. Como metodología se aplicó el Enfoque mixto con alcance aplicativo y propositivo, se realizó un análisis documental de los principales exponentes de costos a efectos de su comparabilidad y propuesta de costos ABC. Los principales resultados son: a) Es compleja la realización del CBA en sus inicios, b) Luego de su implementación el CBA permite la identificación correcta de los costos en forma detallada por cada tipo de unidad o departamento de la Mipyme. Se concluye que la metodología propuesta beneficiará a las Mipymes para su correcta reestructuración y adecuación en cuanto a sus sistemas de costos.
Estrategias de Tratamiento Kinésico de Secuelas Faciales Post Resección de Meningioma Petroclival Izquierdo Mediante Telerehabilitación
Authors: Zalazar Cinat Jessica Andrea Isabel , Leyes Laura Elizabeth , Gerometta Rosana Maria del Rosario
Published: November 2024

La Pandemia por Covid-19, ha representado un desafío para el tratamiento y seguimiento de pacientes en general, pero más aún, en la población de personas con parálisis facial, lo que motivó la implementación de la telerehabilitación como estrategia de tratamiento y seguimiento de dichos pacientes.  Se realizó el seguimiento de una paciente de 51 años de edad, con parálisis facial, de un mes de evolución, presencia de sincinesias y espasmos faciales, secuelas post quirúrgicas de resección de meningioma petroclival izquierdo, tratado durante el periodo agosto 2021 abril 2022. Las sesiones de terapia kinésica se realizaron a través de tele rehabilitación, debido a las restricciones por COVID-19, los recursos terapéuticos se basaron en, educación del paciente durante la sesión, se incluyeron ejercicios de reeducación e inhibición facial frente a un espejo, masoterapia y estiramientos, además se le facilitaron a la paciente, micro videos explicativos con cada técnica realizada durante la sesión. Se utilizaron para la valoración del grado de parálisis y sincinesias, escala de House Brackman, Synkinesis Assessment Questionnaire (SAQ). A la evaluación inicial según escala de House Brackman, se observó parálisis grado V (disfunción severa, parálisis total, asimetría en reposo y movimiento) y se obtuvo un puntaje de 41 en el SAQ. Luego de 8 meses de tratamiento kinésico se obtuvieron los siguientes resultados; HB: parálisis grado 3 (paresia y disfunción leve a moderada) y 25 en el SAQ. Si bien se lograron simetría facial, oclusión completa de ojos, contención de líquidos en la boca y mejoría en la función facial según las escalas mencionadas, los espasmos hemifaciales continúan presentes y la paciente refirió que estos aumentan en frecuencia e intensidad con la fatiga y el estrés
Tecnologías de Información y Comunicaciones para la comunicación efectiva en Adultos Mayores
Authors: Núñez Duré Gilda Elizabeth
Published: November 2024

La tecnología no debe ser privilegio solo de los jóvenes; debe llegar con toda su importancia a los adultos mayores, por consiguiente, surgió la necesidad de integrar a los adultos mayores en el ámbito de la Tecnología, aprendiendo con los jóvenes/estudiantes de la Facultad de Ciencias Aplicadas-Pilar-Paraguay, para la comunicación efectiva entre sus pares, familiares, etc. El estudio consistió en la revisión de la literatura, realizada entre los años 2015 al 2022, mediante un proceso de búsqueda de artículos científicos. Los resultados permitieron identificar los valores de justicia, respeto, tolerancia, diálogo y también la inclusión de tecnología, en la vida diaria como una herramienta para fortalecer los lazos familiares entre adultos mayores, jóvenes y nietos, combinar el componente lúdico de los dispositivos móviles con los contenidos educativos en valores familiares. Con la finalidad de: lograr la integración entre los adultos mayores, jóvenes y nietos de las familias que viven y residen en la Ciudad de Pilar, como también fomentar la actitud positiva hacia la tecnología que proporciona una ayuda imprescindible para facilitar la forma de vida para ellos.
The Effect Of Serum Leptin Level On Subfertility & obesity in Patient With Polycystic Ovaries In Iraqi Population
Authors: Khaleel Zainab ali
Published: November 2024

Abstract:
Background: Subfertility is an expanding problem in the world influencing about 10-15% of the population. Couples with polycystic ovaries female partner usually have an extra risk of being infertile. For different reasons, polycystic ovaries incident is increasing between females. Adipose tissue is a functional endocrine-like organ, that secretes a variety of cytokines and adipokines(mainly Leptin). Leptin, a hormone that is believed to be released by different cell types (mainly by adipocytes) controls energy stores and reflects body fat stores. Elevated serum level of leptin found to be closely impaired oocyte development.
Aim of the study: To determine the association between serum leptin level and body weight in subfertile women with polycystic ovaries.    
Material and methods: A case-control study was done during the period Sep.2020-Jan.2021.The study includes 88 women whose age range from 18-40 years and their BMI ranging between(18.5-40) Kg/m², 44 of them was infertile with polycystic ovaries, and the other 44 women are fertile women with normal ovarian texture. For both groups, leptin levels were measured.
Result: There is a significant association between serum leptin level and subfertility especially in overweight and obese females compared to the control group.
Conclusions: The significant association between serum leptin levels and reproductive capacity in different bodyweight groups especially in females with polycystic ovaries points to the important function of this adipokine in subfertility pathogenesis especially in overweight and obese females in comparison to the control group.
Association between Helicobacter pylori infection IgG and HbA1c in type 2 diabetes mellitus
Authors: Saeed Chiman Hameed
Published: November 2024

Abstract
Background: Infection with Helicobacter pylori has been recognized as a public health problem worldwide. Patients with diabetes mellitus are more liable to infection. The aim of the study was to determine the association between Helicobacter pylori IgGin type 2 diabetes mellitus in Erbil Cityand to find whether H. pyloriinfection associated with higher levels of glycated hemoglobin (HbA1c).
Materials and Methods: The study was a case-control study and carried out at Laila Kasim Health Centre. Around150 type 2 diabetes mellitus patients and 50 non-diabetic patients wererecruited. The study was conducted between September to November 2020.Blood sampleswere collectedand analyzed for blood sugar, HbA1c and serum used for detection of anti-Helicobacter pylori antibody (IgG) by ELISA.
Results:Helicobacterpylori infection was detected in 73.3% of Type 2 diabetes mellitus (T2DM) patients and54% of controls(P= 0.01). Helicobacter pyloriinfection was highly prevalent in patients with fair control of blood glucose (HbA1c 83.8%; P= 0.007).Helicobacterpylori infection was not associated with; duration of T2DM, age, gender, body mass index (BMI), alcohol consumption,dyspeptic symptoms and level of education.
Conclusion:
This study found that the prevalence of H. pylori infection among diabetic patients was significantly higherespecially in those with fair control of blood glucose. This indicates thatH. pyloriinfection could be a potential risk factor for Type 2 Diabetes Mellitus. 
Key word: Helicobacterpylori,Type 2 diabetesmellitus, HbA1c.
Application of Nano-particulate drug delivery systems to deliver therapeutic agents into cancer cells
Authors: Alfuraiji Narjes , Kadhim Weam , Hameed Rana , Chyad Abdulzahra Qasim
Published: November 2024

Cancer is a disorder in which a group of cells grows uncontrollably, disregarding the cell division's physiological rules. Since its discovery (although the word cancer was not used)3000 BC, extraordinary research aims to uncover novel treatment approaches for combating cancer. Currently, over 60% of all ongoing clinical trials worldwide focus on cancer. The selection of treatment depends on the type of cancer, site, and stage of progression. Surgery, radiation-based surgical knives, chemotherapy, and radiotherapy are traditional treatment approaches that are mostly used. Side effects associated with conventional therapy highlight the need for novel cancer treatment. 
Nanotechnology has been widely investigated and utilized for cancer therapy, as nanoparticles play a key role in medication delivery. Nanoparticle-based drug delivery provides several advantages over traditional drug delivery, including better stability and biocompatibility, increased permeability and retention effect, and precision targeting. It has also been proven to tackle the resistance to anticancer drugs by targeting the underlying mechanism such as overexpression of drug efflux transporters, defective apoptotic pathways, and a hypoxic environment, leading to enhance multidrug resistance reversal. Moreover, nanoparticles' role in immunotherapy is undergoing investigation due to their essential role in cancer treatment. This review highlights the role of nanoparticles for drug delivery in chemotherapy, targeted therapy, and the targeting mechanism of nanoparticle-based drug delivery.
outcome of steriod resistant nephrotic syndrome of children in central teaching hospital of pediatrics
Authors: Hasan Faleeha Obaid , Al Ubaidy Mohamed Saad Fadhil , Murad Haider Sabri
Published: November 2024

OUTCOME OF IDIOPATHIC STEROID RESISTANT NEPHROTIC SYNDROME OF CHILDREN IN CENTRAL TEACHING HOSPITAL OF PEDIATRICS
Abstract
Background: Steroid resistant nephrotic syndrome accounts for 10%-20% of all cases of idiopathic nephrotic syndrome. These patients are at risk of developing end stage renal disease.
Aim of the study: to determine the demographic characteristics, renal biopsy findings, response to immunosuppressive treatment, and outcome in pediatric patients with steroid resistant nephrotic syndrome.
Materials and Methods: This retrospective study included 136 children patients diagnosed as primary steroid resistant nephrotic syndrome followed by pediatric nephrology department in central teaching hospital of pediatric during the period from 2000 to December 2015.the study done from June 2016 to December 2016.Age at first episode, gender and familial history of nephrotic syndrome were recorded. Demographic characteristics, clinical features at presentation, renal biopsy findings, response to immunosuppressive treatment and outcome were analyzed.
Results: one hundred thirty six patients involved in the study, Mean age at first episode of nephrotic syndrome was 7.18+_ 3.9 years (range: 1 - 16 years). renal biopsy was done for 83 patients and main histopathology was focal segmental glomerulosclerosis found in 54  patients represent (65.1%).Many items of drugs given to the patients and most common used and most effective drug is Cyclosporine A in which 34(34%) from patients achieved complete remission. There were 21 patients (15.4%) get complete remission, 38 patients (27.9%) lost follow up, 6 patients (4.4%) died, 13 patients (9.6%) developed stage 3 chronic kidney disease 24 patients (17.6%) developed stage 4 Chronic kidney disease and 34(25%) patients developed End stage renal disease. There is significant relationship between hypertension, hematuria, and impaired renal functions at presentation and response to immunotherapy and development of end stage renal disease ,while there is no significant relationship between age of patient at presentation, gender and histopathology with development of end stage renal disease.
Conclusion: we found near half of the patients developed chronic renal failure and 25% developed end stage renal disease. Patients with atypical presentation, resistance to immunosuppressive are liable to develop End stage renal disease significantly .In addition, we found Cyclosporine A is more effective than other immunotherapy as the initial therapy for many patients. However, did not find relation between histopathology and progression to End stage renal disease.
Key wards: steroid resistant nephrotc syndrome, cyclosporine A, chronic kidney disease, end stage kidney disease.
The impact of isotretinoin on platelet and white blood cell count in patient with acne vulgaris
Authors: Abdulwahab Mayday Hadi , Alaa Abdul sahib Jawad
Published: November 2024

Background: Acne is a multifactorial disease and represents a spectrum of disease severity from a couple of blackheads and pustules to severe nodulocystic fulminant acne. The severity of the disease differs from patient to patient therefore Isotretinoin is a commonly used for treating acne. However, isotretinoin may lead to elevated serum levels of triglycerides and cholesterol, and it may affect liver function tests. Moreover, the effect of isotretinoin on hematological parameters remains controversial and examines changes in the blood chemistry panel, hematological parameters of patients diagnosed with acne and treated with isotretinoin.
Methods: This comparative clinical trial carried out at Clinic in the Department of Dermatology in tow hospitals Salahaddin hospital and emergency hospital in Salahaddin city in Iraq. 116 patients were selected. Patients are suffering from acne and divided equally (58 patients each) to one of the two treatment regimens using isotretinoin and doxycycline. Group one was given oral isotretinoin twice daily for seven months and Group two was given doxycycline twice daily for same period. These patients were prepared before the time of study and were followed up during the treatment period. According to female, pregnancy prevented by two contraceptive methods. Both groups are investigated with the same investigations.
 
Results: Among the 116 cases included in the study, (36) were male and (80) were female. The mean age of group one was 21.97±4.87 years and in group two was 21.72±4.95years Mean, platelet count increased, whereas white blood cell count decreased after isotretinoin treatment. But without any statically significant association.
Conclusions: The results of this study revealed that no statically significant effect of white blood cells and platelets count after therapy by isotretinoin.
Keywords: Acne, Isotretinoin, white blood cells and platelets.
Aim of study
 The aim of this study was to assess and compare the efficacy of oral isotretinoin on WBC and platelet count in acne vulgaris patients.
Healthy Lifestyle Behaviors among Medical College Students
Authors: Ali Khamael
Published: November 2024

Background: Countries are impacted by an increase of a group for unhealthy behaviors that strongly contribute to the raise of chronic diseases that have a close connection to daily life behaviors. These diseases include high blood pressure, diabetes, osteoporosis, and cardiovascular diseases. The study aims to assess the healthy lifestyle behaviors among medical college students, and found out relationship between healthy lifestyle behaviors with their demographic characteristics. Methodology: The descriptive research design was conducted at medical colleges in university of kerbala during Sep 26th,2022 to 19th, March, 2023. The sample was collected a non-probability convenience consist of 150 students. The data was collected process has been performed from 4th January to 27th Fepruary,2023. The data were described analyzed through use of a descriptive (frequencies, percentage…) and inferential (Spearman correlation coefficient) statistical analysis procedures. Results: The findings of the study indicated that the majority of the sample were female (68.7%), most of participants were single (88%), the highest percentage of the sample was living at their family (92.7%), and (61.3%) of them resident in rural areas with high monthly income. At last, Concerning the healthy lifestyle activities for students were (79%) at moderate level. Conclusion: The results of this study show more than two- thirds of the sample have moderate level for healthy behaviors. Furthermore, the findings show that there is no significant relationship between students’ healthy lifestyle behaviors with their demographic characteristics. Recommendation: The Ministry of Health should implement an education program through social media to increase level of health awareness among medical college students at Karbala University by highlighting the importance of some curriculum related health.
Association between ER and HER2neu status with various sonographic findings in breast cancer
Authors: Abo Dega Farah
Published: November 2024

Diagnostic ultrasonography  is often  used as a  radiological modality  for assessing  clinically  or radiologically  suspected mammary  lesions based on certain radiological  criteria. This study was conducted to investigate an association between breast sonographic findings and biological markers (ER and HER2\NEU). The study enrolled 100 histological sample of invasive mammary carcinoma diagnosed by core needle biopsy, 52% from the right breast  and 48 % from the left one , age range of patient was from 28 to 80 years with a mean age was 53 years. 64 % were estrogen receptor positive, 54% were HER2\NEU positive. There is a significant statistical correlation between ER and HER2\NEU positivity with the simultaneous   presence of axillery lymph node metastasis. While there is a non statistical relashioship between ER and HER2\NEU positivity with various sonographic findings in invasive mammary carcinoma. Thus, breast ultrasound based findings are of no help to predict ER and  HER2 status of  invasive mammary carcinoma.
The Effect of Parenting Style, Communication Patterns, and Self Efficacyon Adolescent Participation in Family Decision Making
Authors: Simanjuntak Megawat , Rizkillah Risda
Published: November 2024

Adolescence is between childhood and adulthood, where many different developmental tasks must be completed. One of the tasks of adolescent development is to make decisions that in the process, involve parents. This study aims to analyze parenting style, communication patterns and self-efficacy on adolescent participation in family decision making. The research design used was a cross-sectional study design. The population of this research is teenagers from grade 10 to grade 12 who attend SMAN 4 Kota Bogor and SMAN 1 Leuwiliang, Bogor Regency. Sampling in this study was carried out randomly in groups (random cluster sampling) with 323 samples. Data is collected by self-administered. The results showed that the sample self-efficacy included in the moderate category, parents in urban and rural areas had a high authoritative parenting style. Family communication patterns still low. Youth participation in family decision making belongs to the moderate category. One factor that influence a significant negative effect on adolescent participation in decision making was conformity orientation communication patterns. Parents have an essential role in helping improve the ability of children in decision making. Parents begin to involve children in making decisions and build balanced family communication patterns with the orientation of the child and following parents.