bluuebunny/crossref_metadata_2025 huggingface dataset:
Screening the binding affinity of bile acid derivatives for the glucocorticoid receptor ligand-binding domain
Authors: Bjedov Srdjan , Bekic Sofija , Marinovic Maja , Skoric Dusan , Pavlovic Ksenija , Celic Andjelka , Petri Edward , Sakac Marija
Published: January 2023

The necessity of anti-inflammatory drugs such as glucocorticoids has been evident during the COVID-19 pandemic. Glucocorticoids, are the standard therapy for the treatment of moderate and severe COVID-19 patients. However, serious side effects limit the use of these drugs, and anti-inflammatory drugs with better pharmacological properties are urgently required. Bile acids are of interest, because of their anti-inflammatory and immunomodulatory properties, facilitated through an unclear mechanism involving transmembrane and nuclear receptors. In this work, we screened the binding activity of a number of bile acid derivatives, for the ligand-binding domain of glucocorticoid receptor (GR-LBD), the most important receptor for anti-inflammatory processes. Tested compounds include oximes, lactones, lactams, tetrazoles, dienones, C-24 alcohols and cholic acid amides. Cholic acid oxime, deoxycholic acid dienone, 3-keto-24-cholic alcohol and cholic acid amide showed best binding affinities for GR-LBD among tested compounds. The in silico molecular docking explanation is provided. SAR analysis showed that expansion of B and C steroid rings or attachment of heterocycle to C ring is not beneficial for binding; side chain should contain hydrogen donor group; the GR-LBD tolerate well different functionalities on C-3 position. These results provide valuable information toward synthesis of the new glucocorticoids based on bile acids.
Association between Pruritus and Psychosocial Well-being: A Population-based Study among 6,809 Subjects
Authors: Sinikumpu Suvi-Päivikki , Jokelainen Jari , Tasanen Kaisa , Timonen Markku , Huilaja Laura
Published: January 2023

Pruritus has an extensive impact on functional, social and psychosocial behaviour. The association between pruritus and psychological well-being has mostly been studied among selected patient groups, whereas population-based studies are lacking. The aim of this study was to determine the association between pruritus and insomnia, quality of life, depression and anxiety at the population level in the general population. A cross-sectional population-based study was conducted in 2012 to 2013. Study subjects (n = 6,809) belonging to the Northern Finland Birth Cohort 1966 Study participated in a large follow-up study at the age of 45–47 years. They completed an extensive health questionnaire including questions on pruritus and several previously validated questionnaires regarding symptoms of psychosocial well-being. Pruritus affected 19.9% of the study subjects weekly, being more common in women than in men (p < 0.001). A significant association was found between both localized and generalized pruritus and symptoms of insomnia, depression, anxiety and decreased quality of life. The association was seen even in those with mild psychological symptoms/insomnia, and it affected both sexes. The severity of psychological symptoms increased with increasing frequency of pruritus. In conclusion, pruritus has a multiple effect on psychosocial well-being. Physicians should consider possible psychosocial symptoms in patients with pruritus.
Mathematical modeling and design for six sigma
Authors: Tekriwal Prabhat
Published: January 2023

The mathematical modeling (computational fluid dynamics) has been combined with Six Sigma methodology to guide the design of a Range. The concept of Transfer Function development and Robust Design has been explained. A few sample examples including Laser Surface Heating have been included in the context of Transfer Function and Design for Six Sigma. The concept of Lean and its integration with Six Sigma is briefly covered.
Chronologia radiowęglowa stanowisk grupy Gordineşti kultury trypolskiej z północnej Mołdawii i zachodniej Ukrainy
Authors: Król Dariusz , Rybicka Małgorzata
Published: January 2023

Artykuł poświęcony jest problematyce chronologii radiowęglowej stanowisk grupy Gordineşti kultury trypolskiej z obszarów północnej Mołdawii i zachodniej Ukrainy. Bazując na najnowszych datowaniach radiowęglowych i zbudowanych za ich pomocą modelach statystycznych, można sugerować, że osiedle Gordineşti II-Stînca goală mogło funkcjonować wcześniej niż zachodnioukraińskie osady o cechach grupy Gordineşti (np. wołyński Hołysziw). Natomiast rezultaty otrzymane dla stanowiska Winniki-Żupan odpowiadają datowaniu osiedla Gordineşti II-Stînca goală. Uściślenie chronologii mołdawskiej grupy Gordineşti jest również ważne z perspektywy młodszych faz nadbużańskich osiedli kultury pucharów lejkowatych.
Podlaskie cmentarzyska z grobami w obstawach kamiennych w świetle wyników badań interdyscyplinarnych
Authors: Skrzyńska Katarzyna
Published: January 2023

W artykule prezentowane są wybrane wyniki badań projektu pt. „Początki chrześcijaństwa na pograniczu mazowiecko-ruskim”, realizowanego w latach 2013–2016 w Instytucie Archeologii i Etnologii PAN pod kierownictwem prof. dr. hab. Andrzeja Buko. Przedmiotem tych badań były wczesnośredniowieczne cmentarzyska szkieletowe na Podlasiu. Analizy aDNA wykazały, że ludność pochowana w kurhanach genetycznie różniła się od użytkującej tamtejsze cmentarze płaskie – zarówno te z konstrukcjami kamiennymi, jak i bez nich. Antropologiczna analiza porównawcza populacji z cmentarzysk w Surażu i Czarnej Wielkiej wskazuje także na różnice biostrukturalne pomiędzy użytkownikami obydwu typów nekropoli płaskich. Wyniki badań wspierają koncepcję o obcym pochodzeniu ludności pochowanej na podlaskich cmentarzyskach z grobami w obstawach kamiennych oraz co najmniej częściowo tej użytkującej nekropole płaskie założone przy głównych tamtejszych grodach.
Zważyć sacrum? Uwagi nad metodami badań wczesnośredniowiecznych masek z Opola
Authors: Szczepanik Paweł
Published: January 2023

Prezentowany szkic stanowi głos w dyskusji na temat dwóch drewnianych masek z Opola, będących w ostatnim czasie przedmiotem zainteresowania Kamila Kajkowskiego (2021). Celem niniejszego artykułu jest przede wszystkim zwrócenie uwagi na sposoby badania i budowania interpretacji źródeł archeologicznych w kontekście poznania przedchrześcijańskich wierzeń tradycyjnych oraz rekonstruowania elementów obrzędowych związanych z tym systemem. Zostały również ukazane wątpliwości dotyczące sposobów badania przeszłego sacrum, z perspektywy kultury nowożytnej oraz dzisiejszej racjonalności.
Prof. dr hab. Romuald Schild (2.10.1936–23.11.2021)
Authors: Rębkowski Marian
Published: January 2023

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Pembangunan Sistem Informasi Komunitas Ikatan Dosen Katolik Indonesia Berbasis Website
Authors: Arkin Eliezer Julijanto  , Stephanie Pamela Adithama  , Suryanti Ch.
Published: January 2023

Abstrak. Ikatan Dosen Katolik Indonesia (IKDKI) merupakan komunitas dosen Katolik yang hadir untuk menaungi dosen-dosen Katolik di seluruh Indonesia. Salah satu misi dari IKDKI adalah meningkatkan kualitas dosen sebagai pendidik profesional dan ilmuwan melalui penyelenggaraan tri dharma perguruan tinggi. Dengan semakin bertambahnya anggota dari berbagai provinsi, maka fungsi kepengurusan untuk melakukan pengawasan terhadap anggota menjadi semakin sulit. Untuk menyelesaikan masalah tersebut, penulis membangun sistem informasi komunitas berbasis website dengan menggunakan framework Laravel sebagai backend dan framework React JS untuk tampilan pengguna. Sistem yang dibangun akan membantu mulai dari pendaftaran anggota, pengelolaan anggota, pencetakan kartu anggota serta pencatatan aktivitas tridharma perguruan tinggi. Sistem informasi komunitas IKDKI ini telah berhasil dibangun dan dapat memudahkan pengurus maupun anggota komunitas IKDKI dalam mewujudkan salah satu misi IKDKI. Sistem informasi komunitas IKDKI juga dinilai mudah digunakan oleh para pengguna. Dapat disimpulkan juga bahwa pengguna merasa puas dengan adanya sistem informasi komunitas IKDKI ini.

Kata Kunci: Sistem Informasi, Komunitas, Website, Ikatan Dosen Katolik Indonesia
Pengujian Antarmuka Web Perpustakaan Universitas Atma Jaya Yogyakarta Menggunakan Usability Testing
Authors: Nathaniel Jovian Suryono  , Joseph Eric Samodra  , Djoko Budiyanto Setyohadi
Published: January 2023

Abstrak. UAJY memiliki fasilitas perpustakaan yang bisa digunakan oleh para mahasiswa. Perpustakaan UAJY juga memiliki web yang bisa diakses oleh mahasiswa secara online dengan alamat lib.uajy.ac.id. Perancangan tampilan antarmuka suatu web merupakan hal yang cukup penting dalam pengembangan suatu web untuk meningkatkan user experience. Hal tersebut dapat diukur salah satunya dengan melakukan pengujian usability. Pengujian usability dilakukan dengan menguji lima variabel usability menurut Jakob Nielsen yaitu learnability, efficiency, memorability, errors, dan satisfaction. Pengumpulan data dilakukan dengan menyebar kuesioner dengan pertanyataan sebanyak 18 ke 30 orang responden. Pengukuran dilakukan menggunakan likert scale. Hasil yang didapat dari pengujian usability ini adalah web lib.uajy.ac.id memiliki tingkat usability yang “baik” dengan persentase sebesar 72,79%. Kelima variabel yang diuji mendapat hasil usability yang dikategorikan "baik". Selain itu penulis juga membuat rekomendasi perbaikan berupa prototype yang diharapkan bisa membantu pengembangan web lib.uajy.ac.id kedepannya.Kata Kunci: Perpustakaan, Usability, Antarmuka.
Penerapan Metode Logika Fuzzy Dalam Menentukan Jumlah Produksi Optimal Sampul Rapor Pada Percetakan Unika Grafika
Authors: Dimas Yoshua Rama Kurniawan  , Joseph Eric Samodra  , Joanna Ardhyanti Mita Nugraha
Published: January 2023

Abstrak. Indonesia memiliki sistem pendidikan yang menggunakan rapor sebagai laporan guru mengenai perolehan nilai siswa kepada orang tua. Dengan sistem pendidikan tersebut, memunculkan usaha percetakan sampul rapor di Kabupaten Klaten, salah satunya Percetakan Unika Grafika. Percetakan ini sering mengalami kendala dalam proses produksi untuk menentukan jumlah produksi optimal sampul rapor. Logika fuzzy metode Mamdani digunakan dalam penelitian ini untuk menyelesaikan permasalahan. Data yang diperoleh dari pemilik percetakan diolah secara perhitungan manual dan MatlabR2021a. Penelitian ini bertujuan untuk menentukan banyaknya barang yang seharusnya diproduksi oleh Percetakan Unika Grafika. Penentuan jumlah produksi optimal sampul rapor menggunakan variabel permintaan, persediaan dan produksi. Pada metode Mamdani, untuk mendapatkan hasil diperlukan tahap-tahap: (a) Fuzzifikasi, (b) Aplikasi fungsi implikasi, (c) Komposisi aturan, (d) Defuzzifikasi dengan metode centroid. Dari hasil perhitungan menggunakan metode fuzzy Mamdani dengan data jumlah permintaannya adalah 1420 eksemplar dan jumlah persediaannya adalah 385 eksemplar, diperoleh jumlah produksi optimum adalah 3840 eksemplar.Kata Kunci: Permintaan, Persediaan, Produksi, Mamdani, Matlab.
Pembangunan Sistem Informasi Galeri Portofolio Mahasiswa Arsitektur Universitas Atma Jaya Yogyakarta Berbasis Website
Authors: Lilyani Saputri Stevani , Pamela Adithama Stephanie , Joko Santoso Albertus
Published: January 2023

Abstrak. Universitas Atma Jaya Yogyakarta (UAJY) memiliki departemen Arsitektur. Arsitektur adalah ilmu yang mengaitkan seni pada perancangan bangunan menghasilkan produk luaran berupa poster, video, dokumen penelitian. Di UAJY hasil karya mahasiswa disimpan oleh masing-masing mahasiswa dalam bentuk media yang berbeda dan membuat mahasiswa tidak memiliki rekam digital, serta mahasiswa sulit untuk mengelompokkan proyek yang pernah dikerjakannya. Hal ini membuat mahasiswa tidak memiliki portofolio dan Departemen Arsitektur tidak memiliki dokumentasi hasil karya mahasiswa yang dapat ditunjukkan ke masyarakat. Maka dari itu dibuatlah sistem informasi galeri portofolio berbasis website yang menggunakan backend Laravel dan frontend framework Vue.Js. Sistem dibangun untuk membantu mulai pengelolaan data pendukung portofolio hingga pengunggahan berkas hasil karya. Sistem menyediakan fitur share agar pengguna dapat membagikan portofolio kepada masyarakat luar.Sistem Informasi Galeri Portofolio berhasil dibangun dan memudahkan mahasiswa Arsitektur UAJYdalam berbagai hal serta memudahkan mahasiswa memamerkan dan membagikan hasil karya kepada masyarakat umum dan membantu departemen arsitektur menunjukkan kualitas pendidikannya.Kata Kunci: Arsitektur, Portofolio, Galeri, Sistem Informasi, Website
Minangkabau Women’s Politics Participation in the Tradition of Khatm Quran
Authors: Wirdanengsih Wirdanengsih , Erianjoni Erianjoni , Fitrisia Azmi
Published: January 2023

This study concerns on the women of Minangkabau in politics system that is egalitarian and has a central position within the society with the focus on the involvement of women in politics in the process and activities of Khatm Quran tradition which is a part of the local society’s responsibility. Generally, there is a representation of women in politics and local position within the local society. There is a causal relationship between women’s egalitarian characteristics and their positions in politics in daily life. In fact, egalitarian characteristics have a significant effect on the decision making process and in the process and activities of Khatm Quran tradition.
Maarak Bungo Lamang at Maulid Nabi (the Prophet Muhammad's Birthday) Ceremony in Nagari Luak Kapau, South Solok Regency (Study: Form, Procession and Meaning)
Authors: Hidayat Febri , Elida Elida
Published: January 2023

This study explained Maarak Bungo Lamang in Nagari (district) Luak Kapau, South Solok Regency. Maarak Bungo Lamang is one of Nagari Luak Kapau traditions to welcome the birthday of Prophet Muhammad SAW or Maulid Nabi among the people of Nagari Luak Kapau, which still exists today with a study of form, procession, and meaning. This study described the problem of form Bungo Lamang, the procession Maarak Bungo Lamang, the meaning of Maarak Bungo Lamang in the Prophet's Birthday ceremony in Nagari Luak Kapau. This research was conducted with a qualitative approach, with a descriptive method. The data were collected using observation techniques, literature study, interviews, and documentation. The research instrument was the researcher himself as the key instrument. The research location was in Nagari Luak Kapau, South Solok Regency. The informants of this research were the leader of the district (wali Nagari), heads of jorong, artists, religious teachers, traditional leaders, and local communities. The data analysis technique used was the data analysis model of Miles and Humberman in Sugiyono. The results of this study indicated that Maarak Bungo Lamang is a traditional ceremony that has existed for a long time. Starting from Bungo Lamang, which used to be just a cooked lamang decorated with newsprint, has been made to vary with the times. Bungo Lamang consists of cooked lamang decorated with oil paper, cardboard, wood talampuang, shell, etc. The Maarak Bungo Lamang procession is carried out after the prayer midday until before the Asr prayer by surrounding Luak Kapau Nagari from the Nagari border to the field. The community still maintains the meaning of Maarak Bungo Lamang in Luak Kapau Nagari as a form of gratitude for the birth of the Prophet Muhammad or what is commonly called the Maulid Nabi.
Interaksi Pengasuh Asrama dengan Anak Berkebutuhan Khusus dalam Membentuk Karakter di Asrama Sekolah Luar Biasa Negeri Muara Bungo
Authors: Kusuma Aruni Widya , Hasmira Mira Hasti
Published: January 2023

Penelitian ini bertujuan untuk menjelaskan bagaimana interaksi pengasuh asrama dengan anak berkebutuhan khusus dalam membentuk karakternya di Asrama Sekolah Luar Biasa Negeri Muara Bungo. Penelitian ini dilatarbelakangi oleh perilaku tidak baik yang ditunjukkan oleh anak berkebutuhan khusus di asrama, yang dapat menyebabkan penurunan kualitas nilai karakter pada anak berkebutuhan khusus. Penelitian ini menggunakan teori interaksionisme simbolik yang dikemukakan oleh George Herbert Mead. Teknik pengumpulan data yang digunakan dalam penelitian ini yaitu observasi partisipatif, wawancara mendalam, dan studi dokumentasi. Hasil penelitian menunjukkan bahwa interaksi sosial yang dilakukan antara pengasuh dan anak berkebutuhan khusus dalam membentuk karakternya di asrama, dilakukan dengan secara langsung, seperti menyebut nama dan berbicara secara jelas terhadap anak autisme, tunagrahita dan tunadaksa. Dan juga dilakukan interaksi secara tidak langsung, yaitu dengan menggunakan bahasa isyarat bagi anak tunarungu. Sehingga, dengan interaksi yang dilakukan pengasuh dengan anak berkebutuhan khusus, dapat meningkatkan kualitas karakter yang tertanam dalam diri anak kebutuhan khusus. Pembentukan nilai-nilai karakter tersebut antara lain, religius, disiplin, kreatif, mandiri, peduli lingkungan dan peduli sosial. Terdapat satu karakter yang belum tertanam dengan baik dalam anak berkebutuhan khusus, yaitu karakter jujur. Kendala yang dihadapi pengasuh asrama dalam membentuk karakter anak berkebutuhan khusus adalah, dalam penggunaan bahasa yang dilakukan untuk berinteraksi dengan anak berkebutuhan di asrama.
Analyzing a Software Education Experience Based on Stories Told by Elementary School Teachers
Authors:   The Korean Association of Practical Arts Education, Kim Nayoung , Song Hyunsoon
Published: January 2023

This study asked teachers to discuss their experiences with software education in elementary schools. We then explored the meanings of their stories. To accomplish this, we employed the narrative method procedure among four elementary school teachers with experience in software education, thus allowing us to collect data through in-depth interviews. We transcribed these interviews, categorized relevant information, and interpreted the meaning. In this context, we divided the results into stories pertaining to the meaningful experiences of each participant.
Our results were as follows.
First, the participants recognized that software education was necessary, but also reported many difficulties. Second, it began involuntarily, but then grew on its own or remained uninterested. Third, each participant had a different perspective on software education.
In sum, this highlights three important provisions for the successful implementation of software education. First, it is necessary to create an environment in which teachers can experience software education meaningfully. Second, it is important to enhance their understanding of software education. Third, it is critical to reduce the rejection of software education and establish positive perceptions.
Probabilistic Seismic Hazard Analysis of Burdur City
Authors: ALPYÜRÜR Mehmet
Published: January 2023

The aim of this study is to assess seismic hazard for Burdur City (SW Turkey) using a probabilistic approach. A new earthquake catalog for Burdur City and its vicinity, with unified moment magnitude scale, was prepared in the scope of the study. Seismicity of the area was evaluated by the Gutenberg-Richter recurrence relationship. For hazard computation, R-CRISIS (v18) software was used. New Generation Attenuation models were used for analyses. Seismic hazard maps were developed for peak ground acceleration and for bedrock with hazard levels of 2% and 10% probability of exceedance in 50 years. Results of the study show that peak ground acceleration values on bedrock with hazard levels of 2% and 10% probability of exceedance in 50 years change between 0.70-0.75 g and 0.44-0.48 g, respectively.
THE MEANINGFULNESS OF LINGUISTIC EXPRESSIONS FROM THE TRUTH-CONDITIONAL THEORY OF MEANING (A METALINGUAL SYUDY)
Authors: Kusmanto Joko . , Pulungan Anni Holila
Published: January 2023

Meaning is the essence of language. It has been one of the main concerns in the study of language since the age of Plato and Aristotle. There have been various theories of meaning but only a few explains ‘what one knows when s/he is said to know the meaning of linguistic expressions’. Truth-conditional theory of meaning is one of them – not to say the only theory of meaning – which explains ‘what one knows when s/he is said to know the meaning of linguistic expressions’. However, it has been little paid attention to by theorists working on linguistic meaning since the decline of the ideal language philosophy. It happens so because it is basically misunderstood, i.e. the misunderstanding between linguistic proposition and epistemic proposition in the correspondence theory of truth. This paper revives the significance of the truth-conditional theory of meaning in understanding what constitutes the meaning of linguistic expressions when one is said to know it.
LEXICAL RELATIONS IN KELLY CLARKSON’S SONGS
Authors: Guntar Muhammad .
Published: January 2023

This study is about analysis of lexical relations in Kelly Clarkson’s songs. The aim of this study is to find out types of lexical relations by Saeed’s theory that have been found in Kelly Clarkson’s songs and which most dominant lexical relations found in Kelly Clarkson’s songs. This study emerges from the qualitative research. The writer used several Kelly Clarkson’s songs namely Piece by Piece, Breakaway, Dark Side and Miss Independent as the data sources. The finding of this study is categorized by Saeed’s theory namely homonym, polysemy, synonymy, antonym, hyponymy, and meronymy. The results of the study found out synonymy, antonymy, polysemy, homonymy, hyponymy, and meronymy in Kelly Clarkson’s songs. The most dominant lexical relations found in those songs is polysemy. It was found 7 cases from 20 cases in total. Polysemy is a less well-known term than synonym or antonym, although it relates to a far more significant sense relationship. In one word, it can describe two or more meanings.
PEDAGOGICAL TRANSLATION IN ENGLISH TEACHING USED BY TEACHERS IN TEACHER EDUCATION PROGRAM
Authors: Guntar Muhammad . , Sartika Dina . , Mulya Rina . , Elsa Rizky Femilya
Published: January 2023

The purposes of this research were to analyze what situations teachers use translation (from English into Bahasa Indonesia and vice versa) in the Teacher Education Program classes and to describe how the teachers implement the translation in classroom. The research utilized descriptive qualitative method. The participants of the research were two English teachers in high school level in Jambi Province. The data were collected in the form of video recording and then the utterances were transcribed and analyzed based on the theory of situation of using translation proposed by Atkinson (1987), which consists of six situations namely: Eliciting Language, Checking Comprehension, Giving Instruction, Presentation, Checking for Sense, and Language Testing/Language Assessment. The result showed that there were five situations of using translation occurred in this study, they are eliciting language, checking comprehension, giving instruction, presentation and language testing/assessment. Further, pedagogical translation is very useful to facilitate the communication process in the classrooms by interpreting the information received in one language (L1) into another language (FL) and vice versa.
Disparities in the level of regional technical infrastructure development in Poland: multicriteria analysis
Authors: Miłek Dorota
Published: January 2023

Research background: The development policy currently promoted by the European Union is focused on the use of the territory?s internal resources. Among the factors affecting regional development, by building its potential, infrastructure, being a basic necessity for developing activity in a given area, is of significant importance. Hence, investment in infrastructure is critical to stimulating economic dynamism, as it is the basis for supporting a variety of measures aimed at economic growth.
Purpose of the article: This paper aims to evaluate the level of development of technical infrastructure and changes taking place in this field in Polish voivodeships in 2008 and 2020.
Methods: The study was carried out using the Hellwig development pattern method and a comparative analysis of the technical infrastructure of Polish regions. The above approach makes it possible to measure the diversity of the state and availability of infrastructure for the communities of the regions.
Findings & value added: While implementing the study aim, particular attention was paid to the spatial differences in the level of development of the technical infrastructure of Polish voivodeships. The analysis enabled to distinguish groups of voivodeships with the highest, high, low, and very low level of technical infrastructure development. From a long-term perspective, the conducted research can be seen as a contribution to existing research and serve to further compare the impact of technical infrastructure on the economic development of countries. The strength of the study is the adequately long time span of the analysis (2008 ? the period of the financial crisis and 2020 ? the COVID 2019 pandemic), which provides a basis for the formation of the infrastructure in question. The added value of the article is also a regional perspective on the level of development of technical infrastructure using multidimensional methods of statistical analysis. The results of the study can be used to make decisions at the national level regarding the retrofitting of infrastructure in regions with a low level of infrastructure development. For the European Union's decision-makers they can be a source of knowledge of where to direct EU funds the purpose of which is the infrastructural development of regions.
“The national need of sympathy": valor y enseñanza del español como lengua extranjera en Estados Unidos a comienzos del siglo xx
Authors: Albert Ferrando Lorena
Published: January 2023

En el debate en torno al papel de las lenguas extranjeras de finales del siglo XIX en Estados Unidos, las dos estrategias más empleadas eran: la defensa del valor pragmático del idioma en relación con la política exterior norteamericana y la reivindicación de la tradición cultural asociada a la lengua meta. En los textos sobre el español se observa una tercera estrategia: la articulación de una hermandad continental, según la capacidad del lenguaje, para favorecer la comprensión simpatética entre los pueblos. Este trabajo analiza los matices con que los distintos sedimentos de la noción de simpatía infuyen en tal criterio moral.
Efficiency of using aluminum polyoxychloride for purification of drinking water
Authors: Гусятинська Н. А. , Деменюк О. М. , Шульга С. А.
Published: January 2023

Ефективність застосування поліоксихлориду алюмінію для очищення питної води] {Efficiency of using aluminum polyoxychloride for purification of drinking water} 125-136
10.24263/2225-2924-2022-28-6-14
http://nuft.edu.ua/doi/doc/swnuft/2022/6/4.pdf
Imbalanced Samples Fault Detection Using GANCNN for Power Inverters
Authors:   Nanjing Institute of Technology, Sun Quan
Published: January 2023

Aiming at the problem of incomplete fault types existing in power switches fault detection for three phase inverters, a novel diagnosis method based on generative adversarial network (GAN) and convolutional neural network (CNN) is proposed. Firstly, the phase current is used as the fault-sensitive signal, and the fast Fourier transform (FFT) is performed to obtain the frequency domain features, and the normalization preprocessing is performed. Then, the GAN model is used for confrontation training to generate virtual samples by few real sample characteristics, in order to get balanced samples with different fault modes. Finally, convolutional neural network model is built to complete the power inverter fault diagnosis. The experimental results show that GAN-CNN can effectively improve the diagnosis accuracy and stability in the case of sample imbalance.
Egy egészségfejlesztési iroda által, szenvedélybetegek körében megvalósított lelki egészségprogram
Authors: Tóthné Hatházi Anita , Kőpájer István , Kelemen Anett , M. Kornyicki Ágota
Published: January 2023

Szabolcs-Szatmár-Bereg megye hazánk leghátrányosabb helyzetű megyéi közé sorolható. Az ebből adódó nehezített életkörülmények mentális teherként jelentkeznek a megye lakosságát illetően. Számos tanulmány támasztja alá, hogy Magyarországon nagyon magas az egy főre jutó alkoholfogyasztás, mely a dohányzás mellett a legveszélyesebb egészségromboló magatartásforma. A mentális terheltség gyors és átmeneti „megoldására” – a felnőtt lakosság körében – többen az alkoholfogyasztást választják. A fentebb ismertetett információkat figyelembe véve indított szenvedélybetegek részére csoportfoglalkozást egy, a Szabolcs- Szatmár-Bereg Megyei Kórházak és Egyetemi Oktatókórház fenntartásában működő egészségfejlesztési iroda. Betekintést kívánunk nyújtani egy több szempontból hátrányos helyzetű célcsoporttal megvalósított szakmai program részleteibe. Ezen tanulmány segítségével ismertetjük a program terjesztését, előnyeit, korlátait, a program menetét. Bízunk benne, hogy mindez hozzájárulhat az országban található más egészségfejlesztési irodák jövőbeni sikeres munkájához.
Egészségfejlesztési irodák működése: Múlt, jelen és a vízionált jövő
Authors: M. Kornyicki Ágota
Published: January 2023

A magyar lakosság egészségi állapota a születéskor várható átlagos élettartammal mérve az elmúlt években kedvező irányba mozdult el, azonban a többi európai uniós ország egészségmutatóihoz (egészségben eltöltött életévek száma, korai halálozás, megbetegedési és halálozási gyakoriság) viszonyítva továbbra is lemaradásunk van. Ennek hátterében egyfelől a lakosság igen kedvezőtlen életmód tényezői, másfelől az egészségügyi ellátás korlátozott hatékonysága áll. Az egészségfejlesztési irodák elmúlt közel tíz éves működésük során igyekeztek primer prevenciós tevékenységükkel hozzájárulni a lakosság egészségi állapotának megtartásához és javításához. Az egészségfejlesztési irodák eddigi működése hiánypótlónak bizonyult az egészségfejlesztés területén, azonban a hálózat egységes cselekvése érdekében további fejlesztések szükségesek. A hatékonyabb funkcionalitás érdekében a jövőben nélkülözhetetlen egységet teremteni mind a szakmai programok megvalósításának sztenderdjében, mind a fenntartói hatáskörben. Fontos a finanszírozási rendszer összehangolása is, hogy a leszakadó (egészség szempontjából hátrányos helyzetű) területeket minél jobban közelíteni tudjuk a fejlettebbekhez. Kiemelendő, hogy az elmúlt években felmerülő nehézségek ellenére az egészségfejlesztési irodák hálózata és az abban dolgozó szakemberek kitartottak, mivel meggyőződésük szerint nélkülözhetetlen munkát látnak el az egészségügyi ellátórendszerben. A közlemény megkísérli egy területen dolgozó vezető szemüvegén keresztül összegezni az egészségfejlesztési irodák működésének elmúlt időszakát, a jelenlegi helyzetet és a jövőbeli fejlesztendő javaslatokat.
The Relationship Between Environmental Sensitivity, Ecological Attitude, and the Ecological Product purchasing Behaviour of Tourists
Authors: Yayla Özgür , Keskin Emrah , Keles Hüseyin
Published: January 2023

This research was conducted to determine the relationship between environmental sensitivity, ecological attitude, and ecological product purchasing behaviour of tourists. Within the scope of the research, a survey was conducted on foreign tourists who visited Manavgat, Turkey. The Smart PLS program was used to determine the relationships among the variables. According to the results of the research, it has been determined that tourists’ environmental sensitivity has a strong effect on their ecological attitude and their behaviour in purchasing ecological products. Moreover, ecological attitude plays a mediating role in the relationship between environmental sensitivity and ecological product purchasing behaviour. Many suggestions are offered to the academicians, business managers in the sector, and destination management organisations at the end of the study.
Food export restrictions during the COVID-19 pandemic: Real and potential effects on food security
Authors: Kowalska Aleksandra , Budzyńska Anna , Białowąs Tomasz
Published: January 2023

The purpose of the article is to review and critique the implementation of food export restrictions in times of crisis in addressing food security challenges. The methodological approach was to undertake a narrative literature review to outline the challenge of ensuring food security in times of crisis. We explored the problem of food export restrictions introduced in 2007–2008 and 2020 and assessed the changes in the state of food security at the national level during the COVID-19 pandemic using the Global Food Security Index (GFSI). The trade restrictions imposed in 2020 did not play a key role in the increases in international food prices as was the case during 2007–2008 and 2010–2011. The analysis of GFSI values questions whether food export restrictions have been sufficient measures given the size of the food security challenge during the pandemic, and this is a new contribution of this research. The issue of food export restrictions is underregulated in the World Trade Organization (WTO), and this needs to be urgently addressed by another institution, e.g., Food and Agriculture Organization (FAO), given that the war in Ukraine is endangering food security across the world.
Kadmiyum stresi altında yetiştirilen Brassica rapa’da bazı metal taşıyıcı ATPaz’ların anlatımı
Authors: Sahan Merve , Meraklı Nuriye , Memon Abdulrezzak
Published: January 2023

Cadmium (Cd) is one of the toxic heavy metals not essential for the growth and development of plants and other organisms. Brassica rapa accumulates several heavy metals in its leaves and is reportedly suitable for phytoremediation. In this study, Cd uptake and accumulation in the leaves of B. rapa exposed to different cadmium levels (0, 5, 10, 20, 50, 100 μM CdSO4) were analyzed, as well as the effect of Cd stress on HMA2 and HMA4 genes expression were investigated. The qRT-PCR results showed that HMA2 and HMA4 play a vital role in cadmium uptake and translocation in B. rapa at low Cd levels (5-20 μM). However, exposure to high Cd levels (50 and 100 μM) significantly reduced the growth and biomass of B. rapa. Furthermore, high levels of Cd inhibit the expression of HMA2 and HMA4 genes in B. rapa. Our data show a multigenetic (co-acting of many transporter gene clusters) response in the signaling pathway associated with Cd accumulation and tolerance mechanism in B. rapa.
Küresel Salgın ve Türkiye Hayvancılığı Üzerine Etkileri
Authors: Alapala Demirhan Sibel , Şahinler Nuray
Published: January 2023

In this study, the effects of the COVID-19 pandemic process on farm animals in our country were evaluated. The situation in our country has been revealed by examining the available resources on this subject. In addition, information on the characteristics of the COVID-19 agent and the differences between animal species was given, and the production of cattle, sheep, poultry and bee products was examined by examining the number of farm animals. The Covid-19 outbreak has revealed the importance of the food and livestock industry. The continuation of production in the livestock sector prevented a possible food crisis. The Covid 19 epidemic has had some effects on livestock in our country, and there has been an increase in costs along with the global markets. Unfortunately, the increase in costs still continues and puts the producer in a difficult situation. This study has been prepared to contribute to the literature by compiling data on the effects of COVID-19 in the livestock sector and animals.
Bazı Hayvansal Ürünlerin Beslenme ve Sağlık Açısından Önemi
Authors: Alapala Demirhan Sibel , Şahinler Nuray
Published: January 2023

For an adult to have a balanced diet; It is necessary to consume 2800-3000 calories and at least 75- 80 g of protein in a day, and at least 30-35 g of this protein must be of animal origin. Nutrients consist of carbohydrates, proteins, vitamins and minerals. All nutrients contain these compounds to a greater or lesser extent. Although there are these compounds in plant-based foods, animal-based foods such as meat, milk, eggs and honey are rich in protein, as well as the biological value of the protein they contain. When it comes to the use of animal products as a support for the treatment of diseases, the importance of goat’s milk should be emphasized. It is known that goat milk is used in the treatment of many diseases. It has been determined by the positive results obtained from the applications that the regular consumption of goat milk and goat milk products is beneficial in the treatment of eczema, asthma, digestive disorders, some diseases related to varicose veins, virus abscesses and some allergic conditions. “Apitherapy” is a treatment method with bee products and it shows a rapid development in our country. Products obtained from beekeeping activities; products such as honey, pollen, propolis, royal jelly, bee venom. These products are used in many diseases (insomnia, digestive system diseases, upper respiratory tract infections, rheumatic, influenza, orthopedic diseases, skin cancer, eczema, asthma, arteriosclerosis, gastrointestinal diseases, rheumatic diseases, kidney, urinary tract infections, etc.) used as a supplement to treatments. Honey, propolis, royal jelly have excellent antibacterial properties. Bee venom has antirheumatic properties and pollen is used in the treatment of immunological diseases. The importance of animal products in terms of health should

not be ignored and more studies on the subject are needed.
Rooting Performances of Promising Black Mulberry (Morus nigra L.) Genotypes Determined in Tokat Province under Same Environmental Conditions
Authors: Dinçer Emircan , Saraçoğğlu Onur , Öcalan Osman Nuri
Published: January 2023

In this study, it was aimed to examine the rooting performance of hardwood cuttings taken from the promising black mulberry genotypes Kemalpaşa, Yelpe, Merkez 3, Merkez 6, Kocacık, Çamdere, and Merkez 7 determined in the province of Tokat under the same environmental conditions. All cuttings were immersed in 6000 ppm IBA solution for 5 seconds before planting and planted on heated bottom tables. The cuttings, which were kept in rooting units for about 3 months, were then removed and measurements were made on them. As a result of the study, statistically, differences were found in root length, root diameter, root number, callus formation rate and rooting rates in the parameters examined. There was no statistically significant difference between genotypes in decay rates. Decay rates of genotypes are between 12.96% - 41.67%, callus formation rates are between 70.83% - 95.39%, rooting rates are between 60.41% - 92.64%, root lengths are between 5.85 - 7.52 cm, root diameters are between 1.42 - 1.75 mm, and root numbers are between 7.87 - 12.67 root/cutting has taken values. In the light of the information obtained as a result of the study, it was determined that Yelpe, Çamdere, and Merkez 6 genotypes showed high rooting success. These results are important in terms of shedding light on the research to be done in order to determine the various studies and the performance of the saplings. It is also a determining factor for enterprises producing saplings.
Paclobutrazol Uygulamalarının Karadut (Morus nigra L.) Odun Çeliklerinin Köklenme Performansı Üzerine Etkileri
Authors: İşbilir Mehmet Emin , Saraçoğlu Onur , Dinçer Emircan , Donat Alperen , Al-Salihi Ala Asi Mohammed
Published: January 2023

Cutting reproduction is the cheapest and most practical method for plants capable of clonal regeneration. However, the difficulties in adventitious root formation in black mulberry cuttings create a disadvantage for mulberry growers. This study aimed to investigate the effect of IBA and Paclobutrazol applications on the rooting ability of black mulberry hardwood cuttings. The experiment was carried out in the polyethylene greenhouse of Tokat Gaziosmanpaşa University Agricultural Research and Application Center in February 2022. As a material, hardwood cuttings prepared from one-year-old branches of breeding black mulberry trees within the body of the directorate were used. The study was set up in a randomized plot design with 3 replications and 15 cuttings in each replication. In the study, pure water as a control group, 6000 ppm IBA and doses of 1000 ppm, 2000 ppm and 3000 ppm Paclobutrazol respectively were applied to black mulberry wood cuttings separately and together. After the application, the cuttings were planted in perlite medium. The cuttings were kept in the rooting medium for 90 days and then removed; rooting rate, root number, root length and root diameter values were recorded. As a result of the study, the effect of the applications on the root number of the cuttings was not observed while the rooting rate, root length and root diameter parameters were observed. In terms of rooting rate, the best result was obtained from IBA+PBZ 1000 application (40.00%) compared to the control group (0.0%). The highest root length was determined in IBA 6000 application, and the thickest root diameter values were determined in PBZ 1000 application.
Gidya, Leonardit ve Kompost’un Çinko Sorpsiyon Özelliklerinin Belirlernmesi
Authors: Saltalı Kadir , Alhashemi Muhammed
Published: January 2023

Leonardite and compost are used as soil conditioner materials. Gyttja is a material which contains 30-40% lime and 40-50% organic matter with a reserve of approximately 4.8 billion tons in Afşin-Elbistan Thermal Power Plant basin. These materials are used in the production of organomineral (OMG) fertilizers. Zinc (Zn) is one of the micronutrients that plants need. Available Zn deficiency is observed in approximately 49% of Turkish soils. The aim of this study was to determine the Zn adsorption properties of gyttja, leonardite and compost used in OMG fertilizer production. The study was conducted under laboratory conditions. In order to determine the optimum adsorption conditions, the effect of pH, particle size, temperature, shaking time and solution concentration were determined. Then, adsorption properties were determined using linear Langmuir isotherm under optimum conditions. According to Langmuir isotherm, the maximum sorption capacity (qmax) was found to be 14.10 mgg-1 for gyttja, 13.74 mgg-1 for leonardite and 15.67 mgg-1 for compost. In conclusion, Zn sorption values of gyttja, leonardite and compost were consistent with Langmuir and Freunlich isotherms. The maximum sorption capacity (qmax) of these materials is very close to each other. When these data are taken into consideration, it is seen that 1 kg of organic material can sorbed about 15 g Zn. It is useful to take these basic data into account in OMG fertilizer production and sustainable Zn fertilization.
Konya İli Park ve Ev Bahçelerinde Peyzaj Amaçlı Yetiştirilen Dahlia Türlerinde Enfeksiyon Yapan Bazı Virüs Hastalıklarının Serolojik Yöntemlerle Belirlenmesi
Authors: Yeşil Serkan
Published: January 2023

In this study, it was aimed to reveal some viruses that are a problem in Dahlia plants grown for ornamental plants in parks and home gardens in Selçuklu, Karatay and Meram districts of Konya. For this reason, in the 2019 summer, leaf samples were taken from 152 Dahlia plants showing symptoms similar to virus disease symptoms such as mosaic, deformations, yellowing, blight on the leaves and stunted plants. Possible infections of Cucumber mosaic virus (CMV), Tomato spotted-wilt virus (TSWV) and Impatiens necrotic spot virus, (INSV) on these leaves were tested by serological-based DAS-ELISA (Double Antibody Sandwich- Enzyme Linked Immuno Sorbent Assay) method. According to DAS-ELISA results, it was determined that 46.71% of the samples were infected with at least one of these three viruses. In addition, TSWV was detected as the most common virus with a 38.82% relative incidence in the samples, followed by CMV (27.63%). Mixed infections of the viruses were also detected in the leaf samples tested. As a result of the tests, only CMV + TSWV double infection was detected in a total of 30 samples. On the other hand, INSV infection was not detected in any of the leaf samples tested. As a result of survey studies, the average of prevalence rate of virus diseases in Dahlia plants grown in Konya was calculated as 69.56%. Moreover, it was determined that virus diseases were most common in Selçuklu district (75.47%). This is the first report of CMV and TSWV on Dahlia spp. in Türkiye.
Kuraklık Stresi Altında İndol Asetik Asidin Yemlik Soya Fasulyesine Etkisi
Authors: Aksu Gizem
Published: January 2023

Drought is an important environmental stress that limits crop production in the world. Its importance has increased with global warming and it has become one of the most important factors limiting plant production. Soybean is the more source of obtaining and cheaper protein per unit area. Soybean has a widespread use in livestock because it contains valuable amino acids as well as high protein quality. The aim of this research is to diminish negative effect of drought stress in the forage soybean with indole acetic acid application. The experiment was carried out in the growth chamber according to a randomized block design with 4 doses (0-5-10-20 μM IAA) of indole acetic acid, 2 drought levels (0 and -0.5 MPa PEG-6000) and 3 replicate. Leaf length and width, leaf proportional water content, cell membrane damage and malondialdehyde (MDA) content of the plants were determined. The data were evaluated by analysis of variance using a statistical package program. According to the analysis of variance, all parameters were found to be statistically significant in drought x indole acetic acid interaction. Indole acetic acid applied to the forage soybean plant alleviated the damage caused by drought. For this reason, it is thought that it may be important to ensure less damage to plants grown under stress.
Farklı Organik ve İnorganik Gübre Uygulamalarının Mısır Bitkisinin Verimine ve Gelişimine Etkileri
Authors: Durukan Hasan , Duran Zekeriya , Saraç Handan , Demirbaş Ahmet
Published: January 2023

In this study, it was aimed to determine the effects of organic and inorganic fertilizer applications at different rates on the yield and development of maize plant. The research was carried out in three replications in greenhouse conditions, according to the randomized plot design, in plastic pots with a capacity of three kg. Applications in research; control, conventional fertilization, gypsum (1% and 2% w/w), anhydrite (1% and 2% w/w), calcite (1% and 2% w/w), perlite (1% and 2% w/w), vermicompost (5% and 10% w/w) and animal manure (5% and 10% w/w). Maize was used as the test plant. Maize plant was harvested approximately 60 days after planting and analysis of dry matter production and nitrogen, phosphorus, potassium, calcium, magnesium, iron, zinc, manganese and copper were made. According to the results of the research, the highest dry matter production was determined at 15.4 g pot-1 and 10% of the vermicompost application. This application was followed by conventional fertilizer application (13.64 g pot-1). In addition, vermicompost application in general had higher values in macro and micro element concentrations of maize plant.
Causality Analysis and Cointegration Between Mudharabah Financing and Return On Assets In Sharia Business Units Year 2016-2019
Authors: Lubis Delima Sari , Matondang Zulaikha , Siregar Hera Rusliani
Published: January 2023

In increasing profitability, Islamic banks can take advantage of productive assets in the form of financing. One of them is mudharabah financing, the higher the mudharabah financing , the higher the level of profitability of Islamic banks. However, based on data on mudharabah financing with return on assets obtained from the financial services authority, the amount of mudharabah financing always increases every year during the 2016-2019 period. Meanwhile, the percentage of return on assets decreased during that period. The purpose of this research is to find out whether the two variables influence each other or not . The research method is correlation analysis with data analysis techniques used, namely descriptive, normality test, stationary test, lag test, Granger causality test, cointegration test, vector autoregretion (VAR) model test, Impulse Response Function (IRF) test, and Variance Decomposition test. (VD) which is processed using Eviews 10. The results obtained from the causality test are that there is a one-way relationship between Mudharabah Financing and Return On Assets with a probability value of 0.0326 0.05 , but there is no causal relationship between Return On Assets and mudharabah financing.