bluuebunny/crossref_metadata_2025 huggingface dataset:
Existence and concentration behavior of positive solutions to Schrödinger-Poisson-Slater equations
Authors: Li Yiqing , Zhang Binlin , Han Xiumei
Published: February 2023

This article is directed to the study of the following Schrödinger-Poisson-Slater type equation:

−

ε

2

Δ
u
+
V

(

x

)

u
+

ε

−
α

(

I

α

∗
∣
u

∣

2

)

u
=
λ
∣
u

∣

p
−
1

u

in

R

N

,

-{\varepsilon }^{2}\Delta u+V\left(x)u+{\varepsilon }^{-\alpha }\left({I}_{\alpha }\ast | u{| }^{2})u=\lambda | u{| }^{p-1}u\hspace{1em}\hspace{0.1em}\text{in}\hspace{0.1em}\hspace{0.33em}{{\mathbb{R}}}^{N},

where

ε
,
λ
>
0

\varepsilon ,\lambda \gt 0

are parameters,

N
⩾
2

N\geqslant 2

,

(

α
+
6

)

/

(

α
+
2

)

<
p
<

2

∗

−
1

\left(\alpha +6)\hspace{0.1em}\text{/}\hspace{0.1em}\left(\alpha +2)\lt p\lt {2}^{\ast }-1

,

I

α

{I}_{\alpha }

is the Riesz potential with

0
<
α
<
N

0\lt \alpha \lt N

, and

V
∈
C

(

R

N

,
R

)

V\in {\mathcal{C}}\left({{\mathbb{R}}}^{N},{\mathbb{R}})

. By using variational methods, we prove that there is a positive ground state solution for the aforementioned equation concentrating at a global minimum of

V

V

in the semi-classical limit, and then we found that this solution satisfies the property of exponential decay. Finally, the multiplicity and concentration behavior of positive solutions for the aforementioned problem is investigated by the Ljusternik-Schnirelmann theory. Our article improves and extends some existing results in several directions.
Efficiency of early selection for growth and wood quality traits of slash pine in three progeny trials in southern China
Authors: Lai Meng , Dong Leiming , Zhang Lu , Liu Siyu , Wen Jing , Yi Min
Published: February 2023

A firm understanding of the early selection efficiency of ring width and wood quality traits is a prerequisite for breeding of higher growth rates and wood quality of slash pine (Pinus elliottii Engelm.). To accomplish effective early selection for the studied traits, wood core samples were collected from 360 trees of 20 open-pollinated families from three slash pine rotation-aged (harvest age) genetic trials. Wood cores were measured by SilviScan, and the annual patterning, heritability, age-age genetic correlation and efficiency of early selection for ring width, modulus of elasticity (MOE), microfibril angle (MFA) and wood density for early to reference age (age 27) were investigated. The greatest annual ring width was observed at age 4, and this trait decreased gradually toward the bark. Different radial trends were found for MOE and MFA. Wood density was lowest near the pith and then increased steadily with age. Overall, heritability was moderate to high for all area-weighted wood quality traits. Very high age-age genetic correlation values were observed for all traits researched. Estimates of efficiency for early selection indicated that the optimal age of early selection for ring width was 9–12 years, while that for area-weighted MOE, MFA and wood density was 7–8 years.
Intelligent gloves: An IT intervention for deaf-mute people
Authors: Babour Amal , Bitar Hind , Alzamzami Ohoud , Alahmadi Dimah , Barsheed Amal , Alghamdi Amal , Almshjary Hanadi
Published: February 2023

Deaf-mute people have much potential to contribute to society. However, communication between deaf-mutes and non-deaf-mutes is a problem that isolates deaf-mutes from society and prevents them from interacting with others. In this study, an information technology intervention, intelligent gloves (IG), a prototype of a two-way communication glove, was developed to facilitate communication between deaf-mutes and non-deaf-mutes. IG consists of a pair of gloves, flex sensors, an Arduino nano, a screen with a built-in microphone, a speaker, and an SD card module. To facilitate communication from the deaf-mutes to the non-deaf-mutes, the flex sensors sense the hand gestures and connected wires, and then transmit the hand movement signals to the Arduino nano where they are translated into words and sentences. The output is displayed on a small screen attached to the gloves, and it is also issued as voice from the speakers attached to the gloves. For communication from the non-deaf-mutes to the deaf-mute, the built-in microphone in the screen senses the voice, which is then transmitted to the Arduino nano to translate it to sentences and sign language, which are displayed on the screen using a 3D avatar. A unit testing of IG has shown that it performed as expected without errors. In addition, IG was tested on ten participants, and it has been shown to be both usable and accepted by the target users.
Metabolic resuscitation therapy in critically ill patients with sepsis and septic shock: A pilot prospective randomized controlled trial
Authors: Feng Fang , Yang Huyong , Yang Weiwei , Chen Yu
Published: February 2023

The main purpose of our research was to further clarify the effectiveness and potential pathophysiological principles of metabolic resuscitation therapy in critically ill patients with sepsis and septic shock. We found that metabolic resuscitation therapy is beneficial for patients with sepsis and septic shock, shortening the length of intensive care unit (ICU) stay, reducing the duration of vasopressor use, and reducing the ICU mortality rate of patients with sepsis and septic shock, but it does not reduce the hospital mortality rate.
Lycopene ameliorates locomotor activity and urinary frequency induced by pelvic venous congestion in rats
Authors: Zhao Jinchai , Chen Wei , Liu Jian
Published: February 2023

Decreased locomotor activity and altered urinary frequency are induced by bilateral common iliac vein ligation in rats. As a carotenoid, lycopene has a strong anti-oxidative function. This research investigated the function of lycopene in the pelvic venous congestion (PC) rat model and the underlying molecular mechanism. Lycopene and olive oil were administered intragastrically on a daily basis for 4 weeks after successful modeling. Locomotor activity, voiding behavior, and continuous cystometry were analyzed. The levels of 8-hydroxy-2′-deoxyguanosine (8-OHdG), nitrate and nitrite (NO
x
), and creatinine in the urine were measured. Gene expression in the bladder wall was analyzed by quantitative reverse transcription polymerase chain reaction, enzyme-linked immunosorbent assay, and Western blot. Locomotor activity, single voided volume, the interval between the bladder contractions, and urinary NO
x
/cre ratio were all decreased in rats with PC, while the frequency of urination, urinary 8-OHdG/cre ratio, inflammatory responses, and nuclear factor-κB (NF-κB) signal activity were all increased. Lycopene treatment increased locomotor activity, decreased frequency of urination, elevated urinary NO
x
level, and decreased urinary 8-OHdG level in the PC rat model. Lycopene also inhibited PC-enhanced pro-inflammatory mediator expression and NF‐κB signaling pathway activity. In conclusion, lycopene treatment ameliorates PC-induced phenotypes and shows an anti-inflammatory effect in the PC rat model.
Applying solution of spray polyurea elastomer in asphalt binder: Feasibility analysis and DSR study based on the MSCR and LAS tests
Authors: Sun Xiaolong , Yuan Zhengbing , Huang Zhenying , Xu Qin , Zhu Yongqiang , Xu Xinquan , Yuan Junshen , Liu Zhisheng , Zhang Yikang , Chen Qian , Ng Alex Hay-Man
Published: February 2023

The polyurea elastomer (PUA) powder modifier was prepared by the method of spraying–initial crushing–fine grinding, and then, the PUA-modified asphalt was produced. The typical functional structure of PUA was identified and characterized. The apparent viscosity of PUA-modified asphalt was tested at different temperatures. The impact of particle size and content of PUA on creep and recovery properties of asphalt at high temperature was investigated through the multiple stress creep recovery test. The mesothermal fatigue behavior of PUA-modified asphalt was evaluated by means of time sweep and linear amplitude sweep. Results indicated that the high elastic properties of PUA materials might depend on the spherical structure inside PUA material. The diameter of functional structure was around 20 µm and presented as 3D ball structure. The increase in PUA particle size would lead to the increase in cracks and folds in the bonding surface PUA modifier could improve by about 50% of the apparent viscosity significantly. Furthermore, PUA modifier could promote the high-temperature rutting resistance and middle-temperature fatigue property of asphalt. The improving effect on R could reach almost 28% and the 0.075 mm could be the best application size of PUA.
Learning from a Distance
Authors: Mondésir Guinsly , Schoner-Saunders Lisl
Published: February 2023

With the onslaught of the global COVID19 pandemic, universities were forced to quickly pivot to exclusively remote and virtual service options. To further complicate the situation, many international student populations at these institutions were forced to study remotely in their home countries due to the pandemic and visa restrictions. In Canada and Ontario, International students make up a major revenue source for post-secondary institutions, making the need to find viable solutions to continue to serve these populations essential to their financial stability.The Ontario Council of University Libraries (OCUL) runs a shared virtual reference service called Ask a Librarian (Ask). This paper assessed the global pandemic's impact through a comparative study of the service before, during, and after the pandemic's height. Using IP addresses, this study evaluated the impact of geographical location on the user’s access to virtual library resources, as well as identified any barriers, shifts, or trends in the service. The COVID-19 pandemic has changed the face of education and remote learning indefinitely. The hope of this study is to assess the overall success and pitfalls of our current virtual reference services and suggest future improvement areas.
Etiology and Pathogenesis of Postoperative Cognitive Dysfunction (Review)
Authors: Neimark M. I. , Shmelev V. V. , Rakhmonov A. A. , Titova Z. A.
Published: February 2023

Impairment of higher mental functions can complicate the course of the postoperative period even after short and minimally invasive, including laparoscopic, surgical procedures. Postoperative cognitive dysfunction significantly challenges patients’ quality of life, negating real success of surgical intervention and anesthetic support. In some cases, early postoperative cognitive dysfunction may be one of the main predictors of persistent cognitive impairment.

The purpose of the review. To contemplate etiology, pathogenesis and the current perspective of postoperative cognitive dysfunction.

We analyzed 96 publications in various databases (PubMed, Medline, RSCI and others), including 67 papers published over the past 5 years.

The review provides an overview of current definitions and classification of postoperative cognitive dysfunction, data on the prevalence, polyethyology and risk factors, potential impact of the type of anesthesia and surgical intervention on the development of postoperative cognitive dysfunction. Various pathogenetic mechanisms of higher mental functions impairment alongside with available effective pharmacotherapies to correct them were considered.

Conclusion. Numerous adverse factors of the perioperative period, such as neurotoxic effects of general anesthetics, neuroinflammation in response to operational stress and surgical trauma, impaired autoregulation of the cerebral blood flow, imperfect oxygen homeostasis, interactions of neurotransmitter, etc., can potentially cause postoperative cognitive dysfunction. Further deeper insights into etiology and pathogenesis of early postoperative cognitive dysfunction are relevant and necessary to improve prevention strategies and identify most effective pharmacotherapies to correct such disorders.
Predictors of Clinical Efficacy of Cytokine Hemoadsorption in COVID-19 (Clinical Trial)
Authors: Ratnikov V. A. , Sheglov A. N. , Abramovskiy S. V. , Simutis I. S. , Danilov M. S. , Ivanova G. G. , Syrovatskii A. A.
Published: February 2023

Materials and methods. This study analyzed the results of treatment of 62 patients with severe COVID-19 in the intensive care unit using selective hemoadsorption of cytokines. All patients with severe COVID-19 were admitted to the intensive care unit within 14 days from the disease onset were subdivided into two groups. Group 1 patients (n=32) received on a top of standard treatment the hemoperfusion (HP) procedure for 4 hours, for 2–3 days in a row, using a cytokine sorption column composed of mesoporous styrene-divinilbenzen copolymer matrix. Group 2 patients were not subjected to extracorporeal blood purification. All patients received IL-6 inhibitors at a baseline in accordance to the temporary guidelines. We evaluated factors of unfavorable outcomes by analyzing changes in biochemical markers of systemic inflammatory response and mortality rates in patients of both groups.

Results. Initiation of HP later than 10 days from NCI onset (P < 0.001), length of stay in the ICU, extent of lung damage (P = 0.036) and the SOFA (Sequential Organ Failure Assessment) score (P = 0.009) were the most powerful predictors of unfavorable outcome. Levels of systemic inflammatory response markers (interleukin- 6, CRP, D-dimer) in both groups did not significantly affect the survival rates and length of hospital stay (P > 0.05). HP group demonstrated better survival (P < 0.05). Mean hospital stay was 31 and 27 days, ICU stay — 11 and 8 days for Groups 1 and 2, respectively (P < 0.05).

Conclusion. Treatment of severe COVID-19 patients with HP using novel domestic hemosorbent composed of styrene-divinilbenzen copolymer matrix resulted in decrease in CRP levels on the first day after application and, with early onset, contributed to a significant increase in survival and decreased hospital and ICU stay. Additional studies are warranted to clarify the optimal timing of the initiation of HP in severe COVID-19 patients.
Achieving and Maintaining Effective Plasma Concentration of Lithium After Oral Administration
Authors: Makarevich D. G. , Grebenchikov O. A. , Yadgarov M. Ya. , Berikashvili L. B. , Kadantseva K. K. , Likhvantsev V. V.
Published: February 2023

The aim of the study. To study the achievability and contingency to maintain an effective plasma lithium concentration in the perioperative period in patients undergoing carotid endarterectomy (CEAE) with oral intake of lithium carbonate pills.

Materials and methods. It was a prospective study, as a preparatory stage of the multicenter «BINOS» (NCT05126238) RCT. The sample included 15 patients undergoing elective CEAE. In the course of this study, patients were administered oral lithium carbonate, 900 mg per day during 4 perioperative days: two days before the procedure, in the day of surgery and in the 1st postoperative day. Plasma lithium concentration was monitored every 24 hours during all 4 days from the onset of treatment.

Results. Increased plasma lithium concentrations were found in blood samples taken at 48 hours (0.68 mmol/l [0.53–0.84, P = 0.004) and 72 hours (0.68 mmol/l [0.62–0.90, P < 0.001), as compared with the initial values (0.14 mmol/l [0.11–0.17).While during the period between 48 and 72 hours from the onset of treatment the plasma lithium concentration remained in the therapeutic range (0.4–1.2 mmol/l) in 100% of patients.

Conclusion. Oral intake of lithium carbonate pills at a dose of 900 mg/day during 2 preoperative days provided an effective and safe plasma lithium concentration in 100% of patients enrolled in the study.
Childhood obesity and racism: 2022 views and observations
Authors: Marks Ray
Published: February 2023

As obesity continues to pose an immense challenge to mitigate effectively, efforts to untangle its determinants continue, especially those that may exacerbate or impact childhood obesity, and its predictable and well-established multiple often irreversible negative health impacts. Studied for many years in various spheres, the role played by socially derived inequalities, and their long term health effects on youth have not been well studied in this regard, however. This mini review discusses what appears to be a possible insidious and contributing factor impacting various forms of service, resource disparities, and situational opportunities that may explain in part the prevailing and unequal childhood obesity rates between minorities and the mainstream child in the United States. Extracted from current literature, it is concluded that this is a topic of high potential and clinical relevance, and one worthy of intense study, more acceptance and recognition, plus dedicated sustainable collaborative policy goals and supportive efforts.
Presentation of multiple myeloma with absolute lymphocytosis? Coexistence of CLL & multiple myeloma
Authors: Fareed Noorulain , Muhammad Somroo Noor , Fatima Ghulam
Published: February 2023

The presence of a chronic lymphocytic leukemia and multiple myeloma in a single patient is very rare. Multiple myeloma is a plasma cell disorder, whereas CLL (Chronic Lymphocytic Leukemia) is the mature B-cell lymphocytes disorder. We described a 50 year-old man who presented with fatigue and lethargy of 1 month duration. He was found to be anemic, with lymphocytosis, decreased renal function, high calcium level, and conspicuous M-Spike on serum electrophoresis. Furthermore, peripheral smear & bone marrow biopsy demonstrated two distinct hematological malignancies on morphological basis.
Influence of ABO blood group antigen on activated partial thromboplastin and prothrombin time tests in healthy university students kosti city, White Nile state, Sudan
Authors: Elamin Elham , G Tamomh Abdelhakam , M Agena AbdElhadi , Abd Elfatah M Eltaib Rahma , Y Ali Nada , Elmadani Mohammed , F Mohammed Alaa , M Almahdi Fatima , B Musa Mozdlefa
Published: February 2023

Background: Variances in blood group antigen have been related with susceptibility particular to diseases. Prothrombin time [PT], measures the efficiency of the extrinsic and common coagulation pathways, although Activated partial Thromboplastin time [APTT] test evaluates the intrinsic and common coagulation pathways. Objective: To explore the influence of blood groups antigen on APTT and PT among Healthy University Students on different ABO blood groups. Materials and methods: Cross section study including student during the period of three months from September 2020 to December 2020 at Medical campus, University of El Imam El Mahdi, White Nile State, Kosti City, total of 480 students were enrolled. Four milliliters of venous blood was collected from each student, ABO blood grouping was done by the tile method whereas APTT, and PT were analyzed using the manual methods. Data were processed using the Statistical Package for the Social Sciences (SPSS) program version 26 by means of descriptive and inferential statistics. Results: Blood group O was largest among the test individuals [45%], followed by blood group A [30%] and B [16%], while blood group AB has the smallest percentage of (9%). Blood group O is significantly higher APTT value [39.07 ± 4.81] second compared to blood groups A [36.60 ± 5.89] second, AB [35.23 ± 4.86] second, and B [34.39 ± 5.30] second, P value < 0.05. Likewise, blood group A showed a significantly higher PT value [15.94 ± 1.36] second compared to blood groups O [14.12 ± 1.43] second, B [13.54 ± 1.35] second, and AB [14.67 ± 1.80] second, P < 0.05. Male had a higher APTT level (44.44± 7.27] second, PT [15.66 ± 1.88] second, and, compared with the female APTT [35.14 ± 6.49] second, PT [14.08 ± 1.29] second, P value < 0.05. Conclusion: Males have a higher APTT and PT levels compared to females. Blood group [O] individuals having a significantly higher APTT, while blood group [A]individuals having higher PT. This proposal that blood group of individuals may be affect their intrinsic (APTT) and extrinsic Coagulation mechanisms (PT].
Post-transplantation cyclophosphamide as graft versus host disease prophylaxis in patients with acute leukemia received fully matched allogeneic HSCT or haplo-identical HSCT
Authors: Elshamy Alaa , Abd Elmohsen Essam , Denewer Mai , Mabed Mohamed
Published: February 2023

Post-transplant Cyclophosphamide (PT-Cy) has proved efficacy as GVHD prophylaxis regimen after HSCT. However, experiences are limited with controversial results. We herein, assess the efficacy of PT-Cy compared to Methotrexate regimen. Eighty patients with acute leukemia received a fully matched allogeneic HSCT or a Haplo-identical HSCT were analyzed. Group I (Historical group) included 40 patients received Methotrexate, Cyclosporine and MMF. They were transplanted with fully matched allogeneic transplantation. Group II included 40 patients received PT-Cy, Cyclosporine and MMF. They were subdivided to 2 subgroups. Subgroup IIA included 22 patients received fully matched allo- HSCT and subgroup IIB included 18 patients received Haplo- HSCT. Group IIA showed significantly lower incidence of cGVHD when compared to group I with an incidence of 22.7% and 67% respectively (P = 0.002). Group IIA was associated with reduced risk of extensive cGVHD compared to MTX group (P =0.003). No significant differences were found in the incidence of aGVHD, relapse rates, relapse or non-relapse related mortalities, OS and DFS data among the different groups (P>0.05). In conclusion, PT-Cy with addition of IS drugs has statistically significant difference in reducing the incidence of cGvHD in both fully matched and Haplo SCT with less hepatic and renal toxicity.
Respectful maternal care and by who? perspectives of Somali community at IFO refugee Camp, Dadaab, Kenya
Authors: Kituku Jacqueline , Mwoma Teresa , Gitome Josephine , Kahumbi Newton , Ndegwa Priscila , Mainah Muthoni , Bagelman Jen
Published: February 2023

Respectful maternity care is where women are accorded the freedom to make informed choices, protects them from any form of harm and harassment, provides continuous support during labour and child birth and also upholds their privacy, confidentiality and dignity. Previous studies have demonstrated that any care deemed to disrespect the woman may henceforth determine her care seeking behaviour. In the lacuna created by some forms of disrespect of women of child bearing age in the healthcare system, some women may seek alternative care from traditional birth attendants, who are neither skilled nor able to promptly recognize, manage or refer complications arising during pregnancy, labour, child birth and puerperium. Globally, the high maternal mortality rate is associated with preventable complications which occur during pregnancy, labour, child birth and the puerperium, with those who encounter near misses or who narrowly survive death, end up suffering lifelong disability which affects their quality of life. Services offered by traditional birth attendants (TBAs) continue to be sort by a few women of reproductive age in both rural and urban settings including Dadaab, despite the availability of both public and private health facilities. TBAs are preferred among the Somali community as they are deemed to offer a type of care that is regarded as being respectable to the woman and her family as well as being aligned to their culture and religion. Hence, this study aimed to investigate the perspectives of the Somali community residing in Dadaab refugee camps on respectful maternal care. A qualitative study was conducted at Ifo refugee camp in Dadaab, where three TBAs, two save mothers, two married men and two expectant women were interviewed. Two focused group discussions were conducted among the men and pregnant women. The TBAs and the save mothers were interviewed. The TBAs were also video recorded as they performed some of their activities. Data was coded, categorized into thematic areas and the content was analyzed. The findings demonstrated that TBAs and save mothers accorded the women both social and psychological support during pregnancy, child birth, and postnatal period, and treated them with respect. They accompanied the mother throughout the labour and childbirth and gave her so much encouragement. The findings further revealed that cultural beliefs and practices such as prayer, disposal of the placenta and the gender of the care provider, play a big role in maternal care of the women. The placenta is valued as a significant part of the woman’s body and thus has to be buried according to their culture, as opposed to it being disposed of after giving birth in a health facility. Respectful maternal care should be accorded to all women irrespective of their background and should also be culturally sensitive
Evaluation of socio- demographic risk factors for asymptomatic bacteriuria in pregnancy
Authors: Hooja Nupur , Aseri Sapna
Published: February 2023

Background: Asymptomatic Bacteriuria in pregnancy though common often goes undiagnosed till overt U.T.I. occurs. It leads to various maternal and fetal complications. Many factors influence its occurrence. The aim of the study was to evaluate socio-demographic risk factors of asymptomatic bacteriuria. Methods: A hospital based observational study done over one year in the antenatal clinic of a tertiary care hospital. Urine of all the pregnant women was sent for complete microscopy and culture & sensitivity. Socio-demographic profile of all women was noted and data analysed. Results: Of the 450 women included in study, 8.22% had asymptomatic bacteriuria. It was significantly more in the less educated, in those residing in rural and semi-urban areas or belonging to socioeconomic group IV. Conclusion: All pregnant women must be universally screened for asymptomatic bacteriuria. In case it is not feasible, women with high risk factors should be identified and selectively screened.
A comparative study between Patwardhan technique and push & pull method in women undergoing second stage of labor
Authors: Deshmukh Gargi , Bandyopadhyay Tapan , kakade Aniket , Ghosh Asim Kumar
Published: February 2023

Introduction: Obstructed labor with the fetal head impacted in the pelvis is an obstetric complication that requires caesarean delivery with skilful handling in an organized manner to avoid serious maternal and neonatal morbidity. The present study was undertaken to compare the Patwardhan technique with push and pull methods and also to evaluate the safety of Patwardhan technique. Material & methods: Study based on a total 90 pregnant women, of age 18 – 35 years with singleton pregnancy in second stage of labor with deeply impacted head, cases examined in labor room who gave consent and fulfilled inclusion criteria including inpatient admissions and referral randomly allocated in three groups 30 each.1. Patwardhan technique. 2. Push Technique 3. Pull technique. Results: Age, gestational age and duration of labor of the subjects in three were similar. There was significantly less incidence of uterine incision extension to either side, board ligament hematoma, intra-operative blood loss and traumatic Postpartum hemorrhage in subjects undergoing Patwardhan’s technique. With regards to neonatal outcome, wound infection, foetal injury and mean duration of hospital stay were significantly less in Patwardhan’s technique. Birth weight and APGAR scores were similar in all groups. Conclusion: There was less incidence of maternal and foetal morbidity in Patwardhan’s technique which makes it a preferred choice for management during second stage of labor
Magnitude and factors associated with anemia among pregnant woman attending antenatal care in asella town arsi oromia, Ethiopia
Authors: Tadesse Aredo Melese , Fekadu Demise Hailu , Daba Megersa Emebet
Published: February 2023

Background: Anemia during pregnancy affects both the mother and the fetus and is a leading cause of morbidity and mortality in pregnant women in underdeveloped nations. Studies were undertaken in many sections of the nation to assess the prevalence of anemia and predictor variables despite its well-known negative impact on health; however, the topic in Asella has not been well addressed or investigated. Objective: From March 15 to April 15, 2017, pregnant women receiving Antenatal Care services at a public health center in Asella, Ethiopia, were assessed for the prevalence of anemia and its contributing factors. Methods and materials: A facility-based cross-sectional study design was used. Data were collected using an interviewer-administered questionnaire complemented by laboratory tests. Data were collected by face-to-face interviews using a pre-tested, semi-structured questionnaire and the Hg test. EPI ENFO version 7.1 was used for data clearing and documentation, and SPSS version 21 was used for data analysis. The predictors of anemia were found using a logistic regression analysis. To determine the strength of the association, crude and adjusted OR were computed along with their respective 95% CI. P 0.05 was also regarded as statistically significant. Result: The magnitude of anemia was 46.1% in this investigation utilizing a cut level of hemoglobin of 11 g/dl. Anemia was strongly linked with the occupation of merchant (AOR=0.066,95%CI=0.006,0.761), third trimester gestational age (AOR=2.631,95%CI=1.272,5.44), lack of nutrition education (AOR=1.723,95%CI=1.010,2.939), and consumption of wheat as a staple food (AOR=3.288,95%CI=1.765,6.128). Conclusion and recommendation: In the study area, anemia is discovered to be a serious public health issue. A special focus needs to be placed on raising awareness about the consumption of iron-rich and diverse foods among pregnant women and people who work as housewives
Dependent head posture dizziness syndrome: a case report
Authors: Sebastian Deepak , Chockalingam Saravanan , Patel Chetan
Published: February 2023

Dizziness is a symptom frequently encountered in clinical settings and requires a comprehensive differential screening process. The dizziness types commonly referred to rehabilitation are peripheral and central vestibular disorders, vestibular hypofunction, and cervicogenic dizziness. While cervicogenic dizziness continues to present as a diagnosis of exclusion, there is some agreement that cervical mobility is important to maintain vestibular integrity. This case report highlights the importance of cervical mobility in the maintenance of balance and equilibrium. Consequently, its lack thereof, in causing dizziness, is also described. While the relevance of cervical hypomobility to dizziness has been previously described, the possible correlation between cervical hypomobility and dependent postures of the semicircular canals is brought to light. Functional and postural compensations caused by cervical hypomobility which may in turn favor potential otoconia displacement, is described as a speculation. A case study relevant to this speculation is presented. Further research is needed to support and validate this speculation. The importance of restoring functional cervical mobility during routine vestibular rehabilitation is emphasized.
Pediatric cardiopulmonary resuscitation: comparison between emergency department and inpatients setting at a tertiary academic hospital in Oman
Authors: Ramachandran Shilpa , Lal Niranjan , Panchatcharam Sathiya Murthi , Al –Raisi Marwan , Abri Suad Al
Published: February 2023

Objective: The aim of this study was to compare cardiopulmonary resuscitation (CPR) between emergency department (ED) and inpatients setting at Sultan Qaboos University Hospital (SQUH). Methods: The study was a retrospective cohort chart review of pediatric CPR at Sultan Qaboos University Hospital (SQUH) from January 2012 till August 2017. The CPR sheets were reviewed for four main variables: patient related, event related, treatment and outcomes. Results: A total of 83 cases were included, 48 males (58%) and 35 females (42%). Two Thirds of the patients (n=56) were in-patient; whereas one third of cases were from ED (n=27). Overall, most common cause for arrest that accounted 73.5% (n=61) was due to respiratory arrest. Events were more common in younger age group with 50% in less than 1 year (n=41). Bradycardia with hypo-perfusion represented most of arrest type 65% (n=54) followed by asystole 31% (n=26). Only 10% of patient survived to discharge (n=8). In comparison, 89% of ED arrest were unwitnessed. On the other hand, PICU and ward arrests predominantly were monitored 98% (n=55). ED patients’ survival appeared better at 19.2% (n=5) within 24hrs post arrest and 11.5% (n=3) within 1-year in comparison to PICU/Ward of 8.9% (n=5) survival within 24hrs and 1-year post event yet it was not statistically significant. Conclusion: The survival outcome in resuscitation was almost similar between ED & In-patient setting (PICU/wards) cardiopulmonary arrests despite having few significant differences based on variables. Overall, 10% of patients survived to discharge and higher survival rates are associated with duration of CPR less than 20 minutes . Intraosseous route is underutilized and should be applied earlier especially in ED to prevent delay in administration of resuscitation medications.
Ostomy – more than what you see... integrative literature review
Authors: Morais de Matos Sandra Paula
Published: February 2023

Background: Taking into consideration the needs inherent in the new health-disease state, stoma marking can be a turning point in the whole process of transition. Thus, can be considered a factor inhibitor or facilitator, in part due to how it is diagnosed, seen and experienced. Objective: Understand the impact of preoperative stoma marking in context to patients undergoing colorectal surgery. Methodology: Bibliographical research, followed by analytical reading of selected articles and use of the theory of Afaf transitions as theoretical support. Results: The analysis of the scientific evidence, this orients to the recognition of the needs inherent to the candidate the ostomy. Conclusion: Preoperative marking of stoma in context is of great importance as it allows a diagnosis prior to planned nursing interventions associated with a contingency plan facilitates the healthy transition process, resulting in health gains.
Could nebulized heparin be the magic treatment for COVID-19 Pneumonia and ARDS?
Authors: Sewify Khaled , R Shoala Ahmed , Alshaer Abdelaziz , Amin Ashraf , Y AL-Ansari Rehab
Published: February 2023

Background: The global spread of the novel strain of coronavirus referred to as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in the continuous rise in the hospitalization of people suffering from COVID-19 in various parts of the world. The predominant symptoms experienced by patients diagnosed with SARS-CoV-2 infection include pneumonia and acute respiratory distress syndrome (ARDS). These symptoms have contributed to the high mortality rate of COVID-19 patients across the globe. Recent studies have indicated that nebulized unfractionated heparin (UFH) can be employed in the treatment of pneumonia and acute respiratory distress syndrome (ARDS) in hospitalized patients who have been diagnosed with SARS-CoV-2 infection. Case description: The case study for this investigation was a 37-year-old Saudi woman who had muscular dystrophy, bronchial asthma, and diabetes mellitus. This hospitalized patient who was a wheelchair bound was admitted to the intensive care unit (ICU) due to the onset of severe COVID-19 related pneumonia and ARDS. The patient was intubated and placed on high mechanical ventilation support with protective lung strategy (low tidal volume and high PEEP level), prone positioning, administering inhaled nitric oxide therapy, and the intravenous infusion methylprednisolone together with antiviral agents and empiric antibiotics for seven days. Despite the administration of this maximal therapy, she continued to have refractory hypoxemia and severe ARDS. As a result, a high dose of UFH was administered to the patient through nebulization. After administering nine different doses of nebulized UFH, the patient’s oxygenation and inflammatory markers have remarkably improved, then she had a very smooth course and successfully weaned off mechanical ventilation. Conclusion: This treatment strategy resulted in a significant improvement in the P/F ratio, a remarkable reduction in the bilateral lung infiltrates and inflammatory markers and eventually weaning of mechanical ventilation in the COVID-19 patient. This case suggests that nebulized UFH has a strong scientific and biological basis to test its use as a therapy for COVID-19 pneumonia and ARDS as it may offer huge clinical benefit across the time course of the disease as well may prevent progression of infection If administered early at the onset of symptoms, and may finally prevent the needs for mechanical ventilation. Learning points: Randomized controlled trials should be carried out to investigate the clinical impacts of nebulized UFH in both prevention and treatment of COVID-19 pneumonia/AERDS.
OHVIRA syndrome obstetric patient for lower segment caesarean section: peri-operative considerations
Authors: Kumar Amit , Hariharan Uma , Chandran Rejitha , Nagpal Vijay Kumar
Published: February 2023

OHVIRA syndrome is a rare congenital developmental condition manifested by uterus didelphys, lower genital tract obstruction and unilateral renal anomaly. We report a rare case of a full term obstetric patient with OHVIRA syndrome, posted for elective lower segment caesarean section. Peri-operative anaesthetic considerations in a patient with this syndrome have been described. The importances of systemic preoperative assessment and investigations to rule out associated anomalies have also been highlighted.
Optics “clear vision”, storozhynets, chernivtsi region, Ukraine
Authors: Rudkovska Oksana Dmytrivna
Published: February 2023

Manifestation of ocular symptoms in severe covid patients reaches 30% - 60% of cases. This high frequency of involvement of the visual analyzer in the pathological process is explained as follows: the visual system is very energy consuming, and when the general condition of the body is severe, the brain blocks the visual analyzer (motor and / or sensory parts) to pay more attention to other vital organs and systems (paralysis of motor activity of the eye muscles or a significant drop in visual acuity saves brain resources). In severe Covid -19, it is proposed to switch the visual analyzer to "energy saving mode": turn off the pupillary response and accommodation (cycloplegics) and close the eyes with a bandage (for a while). These manipulations (artificial blocking of the visual analyzer) can improve the overall condition of the patient and reduce the risk of blindness.
Comparison of goal-directed and standard therapy for hemodynamic management in heart transplantation surgery
Authors: Benisy Ronak , Saberi Kianoush , Saberi Hossein , Saberi Hasti , Sharifi Shahnaz
Published: February 2023

Background: Significant numbers of patients who undergo major surgery experience postoperative problems, the majority of which are preventable. It has been demonstrated that goal-directed therapy, a method for guiding clinicians in administering fluids, vasopressors, and inotropes, reduces mortality and postoperative complications. However, heart transplant patients were not exclusively investigated. This study focused on patients having heart transplant surgery, which compared the effects of goal-directed versus traditional fluid management. Methods: Goal-directed and standard therapy were examined on 74 patients who had received heart transplantation and were randomly divided into two groups.Using Lidco's CO, CI, SVV, and SVR to track progress toward treatment goals, two groups were compared in terms of fluid repositioning and the use of vasoactive medications.We also compared secondary outcomes like AKI, Cardiac dysrhythmia, CVA, ICU length of stay, and 30-day survival. Results: Both groups had similar baseline characteristics. The goal-directed therapy group had less fluid repositioning. AKI, Cardiac dysrhythmia, CVA, ICU stay, and 30-day survival rates did not differ significantly between the groups; however, Conventional patients spent more time in the ICU. Conclusion: Our data showed that the time spent in the intensive care unit after a heart transplant can be cut in half using GDT. Adverse events occurred in both groups with no statistically significant difference. Preoperative goal-directed therapy needs further well-designed and adequately powered studies.
Comparison of goal-directed and standard therapy for hemodynamic management in heart transplantation surgery
Authors: Sergio Velasco-Villanueva , Ana K Trejo-Olguín
Published: February 2023

Neuroblastoma is the most common solid extracranial tumor in childhood, that arises from neural crest cells. The cervical location is the least frequent and its clinical manifestations are diverse, from cervical mass, dyspnea, stridor, Horner's syndrome or dysphagia. In this case report, we present a male infant with an atypical clinical symptoms, with upper airway obstruction that can occur in multiple contexts, whether malformative or neoplastic masses; Simple and contrast-enhanced neck tomography revealed a lesion in the right posterior cervical triangle with involvement in the retropharyngeal region and significant displacement of the airway. The tumor was successfully excised. The histopathological diagnosis was mixed ganglioneuroblastoma, rich in Schwannian stroma, treatment was started with the COG protocol with 4 cycles of chemotherapy, at the end a control MRI was performed without evidence of tumor recurrence. The importance of recognizing primary tumors with atypical signs and symptoms is highlighted, given that the frequency of neuroblastomas, statistically speaking, is the second cause of childhood cancer, early diagnosis must be made in order to achieve successful treatment.
Fisheries activity in the Bizerta lagoon (South Mediterranean Sea) from the 18th to the 21st century
Authors: Mili Sami , Ennouri Rym , Fatnassi Manel , Bejaoui Safa , Bejaoui Dalel
Published: February 2023

The Bizerte lagoon is characterized by its biological diversity and its wealth of species with high commercial values such as cuttlefish, seabass, seabream, mussels, prawn, and sole, and its fisheries provide employment for fishermen in the area. Indeed, artisanal fishing in the lagoon has been practiced for decades using traps, nets, and mobile gears such as straight nets and lines. The present paper focuses on the diagnosis of the fisheries’ status in this area. This allows us to reflect on the exploitation of the species caught in the Bizerte lagoon since the18th century. Large-scale hydraulic works taking place during the 20th century resulted in a reduction in the water volume inputs, inevitably affecting the fishing activity in the lagoon which we intend to analyze in the present work.
Safety and effectiveness of combining different hyaluronic acid fillers for treatment of facial soft tissue defects: randomized trial, multilayer (“sandwich”) approach
Authors: SO Escobar , MJ Pelli , AB Rey
Published: February 2023

Hyaluronic acid (HA) has been used as a gold standard for aesthetic facial treatments. Many different HA gels are available, and they differ in their HA concentration and rheological aspects. Treating patients with more than one HA gel in the same session or throughout the patient's life is a common practice. We want to show that a combination of different HA is safe and can have a better outcome regarding results, duration, and patient satisfaction. We have treated 30 patients, split into four groups. Patients were treated with three different HA products selected by their G’ to target different facial layers. All products were from the same brand and were injected through a cannula with one point of entry. Patients were evaluated with the WSRS and GAIS scales, showing no difference between groups. A statistically significant difference was seen when compared with basal photos. The follow-up was 12 months. No relevant side effects were detected in all groups. Considering that aging is a transversal process that implicates every facial layer, we conclude that combining different G' HA (multifiller approach) targeting precisecly different layers appears to be well tolerated and increases the average duration of aesthetic effects. More studies should be performed to confirm these preliminary results.
Extravasation injuries in the intravenous therapy with drugs with properties vesicants and irritants in the veterinary medicine of small animals
Authors: Ruggero Errante Paolo
Published: February 2023

The extravasation injuries are uncommon complications during the administration of intravenous therapy in the small animal veterinary clinic. However, the efflux of drugs with vesicant or irritant properties can cause severe and/or irreversible functional and aesthetic changes. The correct catheterization technique and vigilance during intravenous administration of drugs with vesicant or irritant properties are fundamental in preventing the appearance of iatrogenic injuries. The therapeutic approach to this iatrogenic complication involves the combination of non-pharmacological, pharmacological, and surgical measures. In small animal veterinary medicine, there are no uniform recommendations about the best strategy could be adopted, and the interventions described in the literature lack evidence of effectiveness based on scientific studies.
Effectiveness of selected nursing interventions on obstructive sleep apnea syndrome (OSAS) among employees who are at risk in selected institutions, Mangalore
Authors: A Raja
Published: February 2023

Background of the study: Sleep is a physiological and behavioral process that is essential for the proper functioning of the human body. The measurement of sleep quality has become an important clinical tool to identify health problems. Sleep disturbances may be associated with fatigue, mood changes, and decreased pain tolerance. Impaired sleep may lead to metabolic dysfunctions because hormones, which play a vital role in the functioning of the body, are produced and released during the sleep cycle. Obstructive sleep apnea was clinically recognized more than 30 years ago, but awareness of this condition outside the field of sleep medicine was slow to develop. The situation changed drastically when population-based studies uncovered an unexpectedly high prevalence of OSA in adults Health care systems around the world. Aim: The aim of this study was to find out the effectiveness of selected nursing interventions on Obstructive Sleep Apnea Syndrome (OSAS) among employees who are at risk in selected institutions.
Use of omalizumab in women Mexican patients diagnosed with moderate to severe non-atopic asthma: an observational real-life study in a university hospital
Authors: Carlos Herrera-García José
Published: February 2023

ntroduction: While up to 50% of patients with moderate to severe asthma have no evidence of allergy, IgE has been linked to asthma regardless of atopic status. It has already been described that omalizumab, an anti-IgE monoclonal antibody, significantly benefits a subset of patients with non-atopic asthma. Methods: 20 Adult patients who, despite daily treatment with or without maintenance oral corticosteroids, had uncontrolled moderate to severe non-atopic asthma, were assigned to receive omalizumab at doses of IgE levels. The primary endpoint was the change in the clinical and functional parameters of the patients by means of asthma control examination. Results: After 52 weeks of administration of Omalizumab they showed a moderate increase in FEV1, clinical and functional parameters. The symptomatic improvement of the patients was mainly due to an ACT increase of 10 to 20 points. Good tolerance to the drug was also observed, without any serious adverse effects and improvement in the quality of life of the patients. Conclusions: Omalizumab down regulates the expression of FcεRI in patients with moderate to severe non-atopic asthma at the local level, decreasing the multifunctional and immunomodulatory expression of immunoglobulin E (IgE). Omalizumab has a therapeutic role in moderate to severe non-atopic asthma. Our results support the clinical efficacy of omalizumab in Mexican non-atopic asthmatic patients equal to other countries.