bluuebunny/crossref_metadata_2025 huggingface dataset:
Response trajectories of gambling severity after cognitive behavioral therapy in young-adult pathological gamblers
Authors: Granero Roser , Valero-Solis Susana , Fernández-Aranda Fernando , Gómez-Peña Mónica , Moragas Laura , Mena-Moreno Teresa , Pino-Gutierrez Amparo del , Codina Ester , Martín-Romera Virginia , Casalé Gemma , Agüera Zaida , Baenas-Soto Isabel , Valenciano-Mendoza Eduardo , Mora-Maltas Bernat , Sánchez Isabel , Lozano-Madrid María , Menchón José M. , Murcia Susana Jiménez
Published: April 2020

Background and aims

The significant increase in the prevalence of gambling disorder (GD) among young adults in recent years has attracted interest in determining therapeutic efficiency in this sector of the population. The aim of this work was to estimate the response trajectories of gambling severity during the six-month follow-up after a cognitive behavioral therapy (CBT) program in young adult patients and to identify the main variables associated with each trajectory.

Methods

The sample included n = 192 patients, aged 19–35 years old, seeking treatment for GD. Response trajectories were identified through latent class growth analysis.

Results

Three trajectories emerged: T1 (n = 118, 61.5%), composed of patients with severe GD at pre-treatment and good evolution to recovery; T2 (n = 62, 32.3%), with patients with moderate-high GD affectation at baseline and good evolution to recovery; and T3 (n = 12, 6.3%), with participants with severe baseline GD severity and poor evolution after CBT (Abbott, 2019). The highest risk of poor therapeutic outcomes was related to lower social index positions, high emotional distress, high scores in harm avoidance and low scores in self-directedness.

Discussion and conclusions

Differences in the response trajectories at short-term follow-up after CBT reveal heterogeneity in the samples including young and young-adult GD patients. Patients' phenotype at baseline should be considered when developing efficient, person-centered intervention programs, which should comprise strategies aimed at increasing emotional regulation capacities, self-esteem and self-efficacy, with the aim of avoiding relapses in the medium-long term after therapy.
Inhibitory control and problematic Internet-pornography use – The important balancing role of the insula
Authors: Antons Stephanie , Matthias Brand
Published: April 2020

Background and aims

Diminished control over a specific behavior is a core characteristic in addictive behaviors such as problematic Internet-pornography (IP) use. First studies suggest that a hyperactivity of the impulsive system is one reason for impulsive behaviors in the context of problematic IP use. The tripartite-process theory of addiction explains neurocognitive mechanisms beyond common dual-process theories in addictive behaviors. However, the role of the reflective and interoceptive system is still unresolved.

Methods

The study comprised a stop-signal task (SST) including neutral and pornographic images during fMRI and questionnaires to investigate associations between symptoms of problematic IP use, craving, and neural activity of the impulsive, reflective, and interoceptive system. We examined 28 heterosexual males with varying symptom severity of problematic IP use.

Results

Data indicates that individuals with more symptoms of problematic IP use showed better performance in the SST which was linked to decreased insula and inferior frontal gyrus activity during pornographic image processing. An increase in craving was associated with lower activity of the ventral striatum during pornographic image processing. The interoceptive system showed varying effects. Increased insula activity during inhibitory control and decreased activity during pornographic image processing were associated with higher inhibitory control performance.

Discussion and Conclusion

Effects of tolerance and motivational aspects may explain the better inhibitory control performance in individuals with higher symptom severity which was associated with differential activity of the interoceptive and reflective system. Diminished control over IP use presumably results from the interaction between the impulsive, reflective, and interoceptive systems.
Peripherally administered KP-10 prevents development of insulin-induced hypoglycemic shock in diabetic rhesus monkeys
Authors: Qureshi IZ , Fatima I
Published: April 2020

Aim

This study investigated whether kisspeptin-10 (KP-10) prevents diabetic rhesus monkeys from insulin-induced hypoglycemic shock.

Materials and methods

Thirty-six adult male rhesus monkeys were used, six in each group. Diabetes was induced with streptozotocin (45 mg/kg b.w.; single dose i.v.). Groups were as: saline control, insulin alone, pre-insulin (treated with KP-10, 30 min before insulin), post-insulin (treated with KP-10, 30 min after insulin), treated with premix dose of KP-10 (50 μg) and insulin, and the group treated with the kisspeptin antagonist P234 (50 μg). Following an overnight fast, each animal was subjected to respective treatment, and blood glucose concentrations were recorded every 30-min interval for 3 h.

Results

Intergroup comparisons demonstrated that treatment with KP-10 prior to insulin administration and kisspeptin–insulin premix treatment allowed blood glucose levels to rise to significantly higher levels (p < 0.001) by 180 min in diabetic and healthy animals compared to treatment with insulin alone. However, intragroup comparisons revealed a significant decrease in blood glucose level in diabetic animals only. Treatment with P234 antagonist followed by insulin administration abolished the preventive action of kisspeptin, whereby blood glucose decreased significantly (p < 0.001) in both diabetic and healthy animals. KP-10 post-insulin treatment, however, remained ineffective and led, instead, to significantly decreased glucose concentrations by 180 min in both diabetic and healthy animals when compared to animals treated with insulin alone.

Conclusions

KP-10 bears therapeutic potential to prevent hypoglycemic shock that may sometimes occur during intensive insulin therapy. Several pharmacological aspects of its interaction with insulin and other drugs, however, remain to be investigated.
A gyógyszerfüggőség előfordulásának vizsgálata pszichiátriai és addiktológiai rehabilitációs osztályokon kezelt betegek között
Authors: Tóth Viktória , Molnár Beáta , Gazdag Gábor
Published: April 2020

Absztrakt:

Bevezetés: A nyugtatószer-függőség az egész világban, így
Magyarországon is egyre aggasztóbb méreteket ölt. Az egyéb függőségben is
szenvedők, valamint a pszichiátriai betegek különösen veszélyeztetettek a
gyógyszerfüggőség szempontjából. A probléma valós nagyságáról azonban kevés
tudományos adattal rendelkezünk. Célkitűzés: Benzodiazepin
hatóanyagú gyógyszerek használatának vizsgálata egy budapesti kórház
pszichiátriai rehabilitációs és addiktológiai rehabilitációs osztályán kezelt
betegei fogyasztási szokásainak felmérésével és összehasonlításával.
Módszer: A vizsgálat alapjául a két osztály 103 betege
által anonim módon, önkéntesen, interjú során kitöltött, a
nyugtatószer-használati szokásokra, illetve az ezzel kapcsolatos viselkedésekre
vonatkozó, 19 kérdésből álló kérdőív szolgált. Statisztikai
analízis: A demográfiai adatok leírása az átlaggal és a szórással
vagy százalékos arányok megadásával történt. A csoportok összehasonlítására a
minta eloszlásának megfelelően t-próbát, Mann–Whitney-féle U-tesztet vagy
khi-négyzet-próbát alkalmaztunk. Eredmények: A
gyógyszerfüggőségre utaló tünetek, a többféle nyugtató együttes használata,
valamint a nyugtatószedés alkoholfogyasztással történő kombinálása is nagyon
gyakori volt mindkét osztály betegei között. Az eredmények ugyanakkor számos
kérdésnél szignifikáns különbséget mutattak a két mintában. A gyógyszerabúzus
szignifikánsan gyakrabban fordult elő az addiktológiai betegek között, valamint
az illegális csatornákon történő gyógyszerbeszerzés is ehhez a betegcsoporthoz
köthető. A szociális státuszra vonatkozó demográfiai jellemzők, közülük is
kiemelkedő módon a lakhatás, jelentősen befolyásolja a nem orvosi rendelésre
történő gyógyszerfogyasztást. Következtetések: Az eredmények a
gyógyszerfüggőség gyakoriságára hívják fel a figyelmet az addiktológiai és
pszichiátriai betegek között, jelezve, hogy sürgős lépések szükségesek a
probléma visszaszorítása érdekében. Orv Hetil. 2020; 161(15): 594–600.
Kritikus állapotú, légzéstámogatást igénylő COVID–19-fertőzött beteg ellátásának gyakorlati szempontjai
Authors: Végh Tamás , László István , Juhász Marianna , Berhés Mariann , Fábián Ákos , Koszta György , Molnár Csilla , Fülesdi Béla
Published: April 2020

Absztrakt:

2019 decemberében egy új típusú pneumoniajárvány kitöréséről számoltak be a kínai
Wuhan városából, melynek kórokozója egy új koronavírus volt. A kezdetben
állatról emberre terjedő betegség később emberről emberre is terjedt,
világjárványt okozva. A vírus okozta betegség (COVID–19) a tünetmentestől az
enyhe tünetekkel járón keresztül a súlyos, légzési elégtelenséggel, intenzív
osztályos ellátást igénylő spektrumon keresztül változatos formában megjelenhet.
Ez utóbbi betegcsoport ellátása jelentős terhet ró az egészségügyre. Ezen
összefoglaló célja az intenzív ellátást és légzéstámogatást/gépi lélegeztetést
igénylő betegek ellátásának gyakorlati aspektusait hivatott bemutatni. Orv
Hetil. 2020; 161(17): 678–684.
Modern domestic and foreign approaches to assessing the state of economic crime and its impact on economic security
Authors: Splender Viktor , Kozlova Anna
Published: April 2020

The article considers the main domestic and foreign approaches to the assessment of economic crime, defines the essence and highlights the main categories of economic crime, formulates the main characteristics of economic crimes, as well as analyzes statistical data on economic crimes identified in the Russian Federation, reveals their essence and scheme of implementation.

Economic crime is a natural continuation of economic crises, and economic crises are a natural state of the market economy.

There are two main definitions of economic crime:

Economic crime is all crimes against property, that is, by and large, all crimes committed for selfish purposes.
Economic crime is only a crime in the economic sphere.

The most frequently identified economic crimes in Russia are misappropriation of assets, bribery and procurement fraud. That is, these are crimes carried out by employees of companies, or rather by senior employees of companies.

Crimes, the most common in the subjects of the domestic economy, are professional crimes, latent, difficult to prove, and often do not fall under the criminal code. Therefore, while the legislator will change, leading the criminal code in accordance with the requirements of modern economic realities, businesses need to ensure that the system of internal control through risk assessment and study of the revealed fraud, identify factors that contributed to their making, motivation of fraudsters and the conditions under which offenses were possible, to avoid similar situations in the future and to reduce negative impacts, both financial and non-financial.
Economy of joint consumption as a new form of economic relations
Authors: Glukhov Vladimir , Glukhova Zlata
Published: April 2020

Scientific and technological progress, the processes of globalization and internationalization have had a great influence on the development of the economy and related financial instruments, and financial technologies. To describe the model of economic behavior of individuals, the term “joint consumption economy” is widely used, which is based on the joint (collective) use of goods or services that are transferred for temporary use on a reimbursable or free basis. The analysis of information sources by the authors showed that, simultaneously with the term “sharing economy”, other concepts are used depending on the author’s point of view of the researcher and his belonging to the corresponding scientific school. The economy of joint consumption, as a model of the economy, is not new, however, in the context of the penetration of modern information and communication technologies into all spheres of the life of modern society, it received a new impetus for development and changed the structure of the relationship between consumers of goods (services) by reducing the transactional ones that arise in these processes costs, minimizing costs, reducing the number of intermediaries, increasing the number of online trading platforms and simplification of the process of providing consumers with temporary use of goods (services). The online services used in the sharing economy provide consumers with the opportunity to make more efficient, mobile and affordable the use of the resources at their disposal. To single out the volume of the economy of joint consumption among the general indicators of the national (world) economy due to the lack of a unified approach to its determination. For the effective development of the joint consumption economy, the development of the relevant regulatory legal acts is necessary, because for all its advantages there are mutual risks associated with the dishonesty of the parties involved in fulfilling their obligations.
On characteristic values for calculating factors of safety for dyke stability
Authors: Varkey D. , Hicks M. A. , van den Eijnden A. P. , Vardon P. J.
Published: April 2020

Various simplified approaches are used to calculate the characteristic values of shear strength properties, which have then been used in deterministic stability analyses of a dyke cross-section. The calculated factors of safety are compared with the 5-percentile ‘system response’ of the dyke cross-section, calculated using the more exhaustive random finite-element method (RFEM), which is consistent with the requirements of Eurocode 7. The simplified methods accounting for variance reduction due to averaging of property values mostly give factors of safety within 10% of the RFEM solution, whereas the factor of safety based on the 5-percentile material properties is significantly over-conservative.
Carácterización de la especie Chrysobalanus Icaco como alternativa de reforestación para mitigar procesos de erosión costera. Estudio de caso sostenibilidad ambiental de la especie en el departamento de Bolívar-Colombia
Authors: Díaz Mendoza Claudia Patricia , Ayola Mendoza Ledis Paola , Morelo González Yesid Alberto , Díaz Gómez Iván , Burgos Yunelis
Published: April 2020

Objetivo: Estudiar  la especie Chrysobalanus Icaco como alternativa de reforestación para manejo de erosión, teniendo en cuenta el potencial de la especie para la conservación y protección de suelos. Metodología: La metodología que manejó el estudio contempló métodos y técnicas inscritas en investigaciones de campo, descriptiva y correlacional. Resultados y conclusiones: El análisis indicó que la especie puede ser utilizada en el departamento para disminuir procesos erosivos. Sin embargo, las condiciones ambientales deben adecuarse con fertilizantes ricos en oligoelementos para la reforestación con Icaco con fines de aprovechamiento agroindustrial, manejo de erosión y conservación de la especie.
Editorial: Investigación e Innovación en Ingeniería para un mundo sostenible – 4.0
Authors: Forero de Lopez Graciela
Published: April 2020

La Universidad Simón Bolívar presenta este número 1 del Volumen 7 de la Revista Investigación e Innovación en Ingenierías, con la satisfacción de poder hacer evidentes los avances y logros sostenidos durante estos siete años en su objetivo de “publicar artículos de investigación originales, útiles y relevantes que presenten nuevos conocimientos sobre aspectos teóricos o prácticos de las metodologías y métodos usados en todos los campos de la ingeniería”. Por las experiencias, vivencias, el camino recorrido y por el futuro esperado, agradecimientos universitarios muy especiales para quienes han sido el alma de esta Revista: Editora, Co-editora, Comité Editorial, Comité Científico, Soporte Técnico y Tecnológico, Corrector de Estilo, Traductores y sin duda los autores de los artículos.
Perfil do câncer infantil em um estado da Amazônia Ocidental em 2018
Authors: Da Silva Beatriz Onofre Ferreira , Santos Ilná de Matos , Cozendey Mayla Pereira , Da Costa Ruth Silva lima
Published: April 2020

OBJETIVO: Identificar o perfil do câncer infantil em um estado da Amazônia Ocidental em 2018. MATERIAIS E MÉTODO: Trata-se de um estudo transversal, exploratório e descritivo, realizado na unidade de assistência de alta complexidade de um hospital de grande porte do Acre. A população de estudo foi formada por 49 crianças de 0 a 10 anos com diagnóstico de câncer e atendidas no local de estudo no ano de 2018. RESULTADOS: Os dados apontam que a maioria das crianças (38,8%), encontrava-se na faixa etária entre 05 a 07 anos, do sexo masculino (57,0%), de cor/raça parda (34,7%), e a maior parte delas eram procedentes do município de Rio Branco (39,0%).  Os tipos de cânceres mais frequentes foram leucemias (48,0%), seguido do câncer do sistema nervoso central (18,0%) e do sarcoma de partes moles (10,0%). Frente ao ano do diagnóstico prevaleceu o ano de 2018 com 19 casos e observa-se ainda que o número de ocorrências apresentou uma tendência de crescimento a partir do ano de 2015. Quanto ao desfecho dos casos, a maioria das crianças seguem em acompanhamento 40 (82,0%), sendo que 6 (12,0%) evoluíram para óbito e 1(2,0%), para cura. CONCLUSÃO: Observou-se que o câncer infantil é problema atual e crescente, predominado em crianças de 2 a 7 anos, do sexo masculino, de cor/raça parda. A leucemia e a quimioterapia representaram o tipo de câncer e o tratamento, respectivamente, mais frequentes. Recomendam-se estratégias que contemple o diagnóstico e tratamento precoce para o enfrentamento do problema.
Detection of five bacterial pathogens of rice by multiplex PCR v1
Authors: Bangratz Martine , Tollenaere Charlotte
Published: April 2020

This multiplex PCR protocol is used for the detection of five bacterial pathogens of rice : Pseudomonas fuscovaginae, Burkholderia glumae and gladioli, Pantoea spp, Xanthomonas oryzae, Sphingomonas spp.
Pillowcase & rubber band DIY face mask v4
Authors: Turnsek Jernej
Published: April 2020

This protocol describes a very simple way to make a face mask at home using a cotton pillowcase, a (coffee) filter, 2 rubber bands, and a minute of your time. Wearing a face mask helps stop the spread of the new coronavirus. Useful additional resources: 1/ Video protocol for a related face mask alternative. 2/ More DIY face mask ideas via the Center for Disease Control and Prevention. 3/ Pillowcase alternatives and strategies to improve/modify (the effectiveness of) your DIY face mask. 4/ Discussion on sneeze/cough droplet ballistics and why wearing a mask, even a DIY cloth-based one without filters, matters.
PhotoId-Whale: blue whale dorsal fin classification for mobile devices v1
Authors: I Ramos-Arredondo Rosa , E Blanca , Gendron Diane , Francisco Gallegos-Funes J. , Mújica-Vargas Dante , Rosas-Fernández J.B.
Published: April 2020

Photoidentification is a method used by biologists to classify animals primarily to track endangered species. Different methods of identification, either manual or computational, have been developed since the 1990s, which until now have remained in use. However, these methods can introduce a factor of subjectivity when classifying an individual animal, creating uncertainty or inaccuracy in the results obtained as a result of the human criteria involved. For this reason, one of the main objectives in photoidentification is to implement an automated mechanism that is free of biases, is portable, and is easily used. The main aim of this work is to develop an autonomous and portable photoidentification system through the optimization of image classification algorithms that have high statistical dependence, with the goal of classifying images of the dorsal fin of the blue whale through offline information processing on a mobile device. The new proposed methodology is based on the Scale Invariant Feature Transform (SIFT) that, in conjunction with statistical discriminators such as the variance and the standard deviation, fits the extracted data and selects the closest pixels that make up the edges of the dorsal fin of the blue whale. In this way, we ensure the elimination of the most common external factors that could affect the quality of the image, thus avoiding the elimination of relevant sections of the dorsal fin. The blue whale photoidentification method presented in this work has been developed at the Instituto Politécnico Nacional on the coast of Baja California Sur. The results shown have been validated qualitatively and quantitatively in terms of sensitivity, specificity and accuracy on the Jetson Tegra TK1 mobile platform. The presented solution balances the results obtained with the computational cost of the execution of the algorithm, and yields a portable system that could be beneficial for field studies.
Colony PCR (Protocol for Promega GoTaq) v1
Authors: Zurbruegg Mark
Published: April 2020

This protocol explains how to use the GoTaq Dna polymerase kit from Promega to perform colony PCR. "GoTaq® DNA Polymerase contains GoTaq® DNA Polymerase, 5X Green GoTaq® Reaction Buffer and 5X Colorless GoTaq® Reaction Buffer. The enzyme is a Taq DNA polymerase supplied in a proprietary formulation containing 50% glycerol with buffers designed for enhanced amplification. The 5X Green GoTaq® Reaction Buffer contains two dyes (blue and yellow) that separate during electrophoresis to monitor migration progress. The colorless buffer is used when direct fluorescence or absorbance readings are required without prior purification of the amplified DNA from the PCR. Both buffers contain MgCl2 at a concentration of 7.5mM for a final concentration of 1.5mM in the 1X reaction." -Promega instructions
Oral Glucose Tolerance Test in Mouse v1
Authors: Smith Nancy , Ferdaoussi Mourad , Lin Haopeng , E Macdonald Patrick
Published: April 2020

This protocol details the oral glucose tolerance test in mice. This is performed on C57Bl6, transgenic SENP1 KO and ZMIZ1 KO mouse models. Typically GTT's are done at 12 weeks of age. Following the GTT on chow diet, some mice are put on high fat diet for the next 10 weeks. Subsequent glucose tolerance tests are performed following 2 days, 4 weeks and 8 weeks of high fat diet. Insulin tolerance test can also be performed. Once the in vivo studies are complete, the pancreas or islets are isolated for further ex vivo experiments.
IP Glucose Tolerance Test in Mouse v1
Authors: Smith Nancy , Ferdaoussi Mourad , Lin Haopeng , E Macdonald Patrick
Published: April 2020

This protocol details the IP glucose tolerance test in mice. This is performed on C57Bl6, transgenic SENP1 KO and ZMIZ1 KO mouse models. Typically GTT's are done at 12 weeks of age. Following the GTT on chow diet, some mice are put on high fat diet for the next 10 weeks. Subsequent glucose tolerance tests are performed following 2 days, 4 weeks and 8 weeks of high fat diet. Insulin tolerance test can also be performed. Once the in vivo studies are complete, the pancreas or islets are isolated for further ex vivo experiments.
The Comparison of Student Creative Thinking Skill using CBL Implemented in STEM Education and Combined with PSL Worksheet in Indonesian School
Authors: Putri Noviana , Rusdiana Dadi , Suwarma Irma Rahma
Published: April 2020

The main goal of this study is to present the effectiveness improvement of student’s creative thinking skills using CBL implemented in STEM education and CBL combined with worksheet PSL. The STEM education perspective used in this study is a separate science discipline (Physics) that incorporates other disciplines. The research method used in this study is a quantitative method with a quasi-experimental research design. The research includes a pre-test-post test control group design. The subjects of the research consist of forty-five students in 10th grade of one of the vocational schools. The instrument used in this study is an essay test consisting of four questions with indicators of fluency, flexibility, and originality. The enhancement of students’ creative thinking skills is known by analyzing normalized gain (g) on the experimental group and control group. A non-parametric test and Cohen’s Kappa test were used to examine differences improvement of student’s creative thinking skills with the IBM Statistics SPSS 20.00 program at .05 significant levels. As a result of the research, it was found that CBL implemented in STEM education has a higher improvement for students of creative thinking skills than CBL combined with worksheet PSL. CBL implemented in STEM education also has a major impact on improvement of students’ creative thinking skills.
La elusiva seguridad humana del Tratado de Libre Comercio Colombia-Canadá. La minería en el municipio de Buriticá, Antioquia
Authors: Restrepo Parra Adrián Raúl
Published: April 2020

Este artículo aporta elementos de evaluación del Tratado de Libre Comercio (TLC) Colombia-Canadá a partir del estudio de la implementación de la minería en el municipio de Buriticá, departamento de Antioquia, donde la empresa Continental Gold dirige la explotación de una de las minas de oro más importantes del país. Por eso está enfocado en el supuesto central de esta política, el cual exige a la empresa generar riquezas y promover la seguridad humana. Por eso, este Tratado incluyó un capítulo sobre derechos humanos, algo inédito en este ámbito. El artículo recurre a la teoría del Estado en acción y la perspectiva metodológica del análisis de política pública —policy analysis—. Aunque la metodología de la investigación combinó técnicas cuantitativas y cualitativas, la principal técnica aplicada fue una encuesta. Los resultados del estudio permiten discutir los alcances del postulado central del TLC, particularmente porque su implementación en proyectos de extracción minera genera conflictos en los cuales la empresa resulta implicada y el Estado cuestionado en su rol de proteger, remediar y hacer respetar los derechos humanos.
De línea en el desierto a espacio de sociabilidad. El discurso informativo de la prensa chilena sobre la frontera entre Chile y Perú (2014-2015)
Authors: Bello Arellano Daniel , Chiuminatto Orrego Magglio Gino
Published: April 2020

Este artículo analiza los discursos informativos sobre la frontera entre Chile y Perú publicados por la prensa chilena, con el objetivo de identificar y contrastar las diversas propuestas narrativas que intervienen en el proceso simbólico de construcción de la realidad fronteriza. De este modo se busca, por un lado, contribuir al estudio de un territorio tensionado por disputas bilaterales de larga data, constantemente creado y re-significado en y por los discursos públicos; por otro lado, comparar el rol de los medios nacionales y locales en dicho proceso creativo. El trabajo permitió identificar dos formas distintas de entender y narrar la frontera, que pueden sintetizarse en dos imágenes: la de una línea en el desierto y la de un espacio complejo de sociabilidad.
Recirculating aquaculture system with three phase fluidized bed reactor: Carbon and nitrogen removal
Authors: Sánchez-Ortiz Iván Andrés , Cárdenas-Calvachi Gloria Lucía
Published: April 2020

The core objective of the study was to evaluate the organic matter and nitrogen removal efficiency in a recirculating aquaculture system for the intensive laboratory-bred rainbow trout. The treatment system consisted of an upflow reactor which operated at a hydraulic retention time (HRT) of 18 and 36 min, a pre-filtration unit with HRT of 4.9 and 9.8 min, a three-phase airlift fluidized bed reactor operated at HRT between 5 and 11 min, a granular unit for the upflow and the fluidized bed reactors effluents filtration with 5.8 and 11.6 min as HRT, and an ultraviolet (UV) unit for the final effluent disinfection. A plastic material was used as support media in the upflow reactor, and granular zeolite with an effective size of 1.30 mm in an 80 g/L constant concentration was used as a carrier for the fluidized bed reactor. Average removal efficiencies of biochemical oxygen demand (BOD) chemical oxygen demand (COD), ammonium, nitrite, nitrate, and total nitrogen were 94.4, 91.7, 52.5, 13.4, 1.3 and 6.0% respectively. In the rainbow trout rearing tanks, there was a water volume of 125 L and water exchange rates of 125 and 250 L/h, there were no registered mortalities; the calculated daily weight gains were 1.55 and 1.51 g/day and the final stocking densities were respectively 20.87 and 20.58 kg/m3. The results suggested that the system had the capability to develop a nitrification process for maintaining water quality characteristics within the recommended values for rainbow trout farming, but total nitrogen was not effectively removed due to the weak denitrification process, since there were modest values of nitrite and overall nitrogen removal.
A Method to Identify Geochemical Mineralization on Linear Transects
Authors: Mikšová Dominika , Rieser Christopher , Filzmoser Peter , Thaarup Simon Mose , Melleton Jeremie
Published: April 2020

Mineral exploration in biogeochemistry is related to the detection of anomalies in soil, which is driven by many factors and thus a complex problem. Mikšová, Rieser, and Filzmoser (2019b) have introduced a method for the identification of spatial patterns with increased element concentrations in samples along a linear sampling transect. This procedure is based on fitting Generalized Additive Models (GAMs) to the concentration data, and computing a curvature measure from the pairwise log-ratios of these fits. The higher the curvature, the more likely one or both elements of the pair indicate local mineralization. This method is applied on two geochemical data sets which have been collected specifically for the purpose of mineral exploration. The aim is to test the technique for its ability to identify pathfinder elements to detect mineralized zones, and to verify whether the method can indicate which sampling material is best suited for this purpose.
THE IDENTIFICATION OF THE PRODUCTIVE STRATA WITHIN TYNIV-HRUSHIV OIL AND GAS FIELD
Authors: Fedoryshyn D. , Bagriy I. , Trubenko A. , Fedoryshyn S. , Khovanets N.
Published: April 2020

The findings of the geological and geophysical researches reveal the high prospects of Krukenychi Depression in terms of new deposits discovery. Notably, some productive reservoir rocks have been indentified within the Neogene formations of Tyniv-Hrushiv Oil and Gas Field. The major gas capacity is associated with the lower Dashava deposits; that is supported by considerable well rates which were apparent within previously discovered fields.

According to the readings of the geophysical well logging, the correlation pattern of prospective strata distribution has been introduced; as a followup, it has been determined what the fluid content is within the lower Dashava age. Consequently, just over the gas-bearing reservoir rocks, the waterbearing strata have been located. The geological structure of the lower Dashava age is featured by the two-meter unit of claystones and siltstones which separate the water-bearing strata from the productive ones. The very feature of the geological structure causes the encroachment of productive horizons; that is proved by the well testing results. The more thorough researches help to define the key factors which influence the distribution of the sand material through the section of the Sarmatian age. Furthermore, it is possible to set up a water and gas ratio within the productive strata.
DEPENDENCE OF MECHANICAL SPEED OF WELL DRILLING ON THE PORE PRESSURE OF PENETRATED BEDS WITHIN THE PRE-CARPATHIAN FIELD
Authors: Chornyi E.
Published: April 2020

The paper considers the dependence of the mechanical speed of wells drilling on the seams with abnormally high spatial (reservoir) pressures. Forecasting of AHRP is important for improving the degree of completion of layers in process of drilling. As a result of the drilling in of unpredictable areas of AHRP in the Pre-Carpathian region the drill columns often get stuck, one of the reasons for which is not often a justified preventive weighting of the drilling mud. To regulate the pressure in the well during drilling, it is necessary to identify the upper limit of the AHRP zone in time and give it a reasonably quantified characteristics. After analysying the data of wells in the Pre-Carpathian region and those that are being drilled now, it was possible for us to establish that in the case of approaching the well bore to the formation of AHRP, there is an increase in the mechanical speed of drilling in clay rocks, due to the presence of increased inernal pressure and a lower density of these rocks. Increasing of the mechanical speed of drilling under the condition of constant parameters of the drilling regime is also due to heterogeneity of rocks, and stratigraphic transitions from one fold to the other. However, in the case of a double increase of the mechanical speed of drilling in sedimentary layers which are identical in lithology, it is possible to confidently explain this phenomenon by the entrance of the borehole into the AHRP zone. In order to verify the possibility of using mechanical logging to predict the areas of AHRP directly during drilling, we compared the change in the mechanical speed of drilling along the well bore with the data of quantitative and qualitative determination of the areas of AHRP on the results of industrial-geophysical research. Qualitative and quantitative estimation of AHRP zones was carried out, basically, according to the data of electrometry of wells, using the technique of "curves of normally densified clay". For the verification of the findings, direct measurements of the formation pressure with the pressure gauges were used and the data of determination of the formation pressures in the case of transfer of clay solution from the well. Due to the prediction of spatial and reservoir pressures by means of mechanical logging in the process of well laying, we observe a decrease in accidents rate, and an increase in the efficiency of drilling.
MANAGEMENT OF SUSTAINABLE MINING OF COAL RESOURCES IN UKRAINE
Authors: Volkov V. , Horoshkova L. , Khlobystov Y.
Published: April 2020

The dynamics of coal resources mining in Ukraine are analyzed in the article. It is proved that there were indices fluctuations, i.e. volumes of extraction, and growth rates during 10 years. The approximation of growth rates of coal mining resources by polynomial function using the trend line is made. It is determined that studied indices fluctuation have cyclical pattern, correlate to each other and depend on country`s economic and political situation. It is proposed to make forecasts of the extraction volumes based on national cyclical economic development. It is proved that balanced mining should solve the problem of mineral deposits sustainable exploitation. It is proposed to use the patent-protected author's methodology to forecast the development of complex systems to manage sustainable mining of coal resources in Ukraine. The developed model will allow managing volumes of extraction of technologically related minerals in correlation with the volumes of exploitation.
Experience of the Implementation of the Modular Principle in the Training of Primary School Teachers
Authors: Budnikova S.P.
Published: April 2020

The article presents the results of participation of the Tula State Lev Tolstoy Pedagogical University in the second and third stages of approbation of the basic professional educational program in terms of education bachelor degree with the direction: 44.03.05 "Pedagogical education (with two profiles of preparation)", profiles of preparation: Primary education, Foreign language; Primary education, Informatics. This project was implemented on the basis of an agreement on network interaction concluded with MSUPE. Approbation was attended by students 4 and 5 courses. The content, the course of implementation and the main results that were achieved by the students in the course of approbation and the formation of their professional subjectness were analyzed. The results of the pilot approbation of the toolkit of independent evaluation of the formation of the general professional competencies of students are also considered. The difficulties that were discovered during the practice process were classified. The project was tested within the framework of the Federal target program of education development for 2016–2020.
Hemostatic system parameters and level of magnesium in patients with beta-thalassemiа
Authors: Aliyeva N R
Published: April 2020

Aim. To study the hemostatic system parameters and magnesium levels in patients with beta-thalassemia.

Methods. The object of the study was the blood serum of 96 women with beta-thalassemia: 46 patients with intermediate beta-thalassemia and 50 patients with beta-thalassemia minor, without clinical manifestations of hypercoagulation. The blood serum of 30 healthy donors was used as the control group. It was studied hemostasis system parameters: platelet count activated partial thromboplastin time (aPTT), prothrombin time, plasma fibrinogen level, D-dimer level, euglobulin clot lysis time, antithrombin III activity. The serum magnesium level and risk of deficiency were determined using the MDQ questionnaire.

Results. In patients with intermediate beta-thalassemia, an increase in the level of thrombinemia marker D-dimer (500 ng/ml) was revealed. Patients with intermediate beta-thalassemia were divided into two groups according to the revealed level of D-dimer: 14 (30.46.8%) patients with latent hypercoagulation in group 1 and 32 (69.66.8%) patients without latent hypercoagulation in group 2. It was found that in the group with a high levels D-dimer, fibrinogen level was increased (p 0.05), fibrinolysis time was prolonged (p 0.05), activated partial thromboplastin time was shortened (p 0.05), and antithrombin III activity was slightly reduced (p 0.05). The serum magnesium level in patients of the first group was lower (t=7.3; p 0.001), and the risk of deficiency in the questionnaire was higher than in patients of the second group (r=0.785, p 0.05). Hemostasis and magnesium levels in patients with beta-thalassemia minor did not differ from the control group (p 0.05).

Conclusion. One-third of patients with intermediate beta-thalassemia have a pre-thrombotic state for hemostasis latent hypercoagulation and magnesium deficiency which can be predictors of clinical signs of thrombosis.
Causes of hypocalcemia after thyroid surgery
Authors: Hummatov A F , Abbasov A H , Ismayilov A K , Gasymov E M
Published: April 2020

Aim. To identify the causes affecting hypocalcemia and its frequency of causing after thyroidectomy.

Methods. The study included 402 patients after thyroidectomy, 361 (89.8%) women and 41 (10.2%) men, for the period 20152019. The patients were between the ages of 14 and 77 years (average 4527.2 years). Patients were tested for the presence of hyperthyroidism, the volume of tissue removed and type of thyroidectomy, presence of repeated thyroid operations and accidental parathyroidectomy, the results of parathyroid autotransplantation and pathohistological reports. To determine the effect of these factors on hypocalcemia, patients were divided into three groups. The first group included patients (n=51, 12.7%) were underwent surgery for Graves disease, the second (n=335, 83.3%) for nodular goiter, and the third (n=16, 4%) for recurrent goiter. Statistical data analysis was performed with IBM SPSS 16.0. The results were analyzed by one-way analysis of variance or KruskalWallis test and the median test. Results were considered statistically significant at p 0.05 (two-sided criterion).

Results. In the early postoperative period, 20 (5%) of 402 patients had hypocalcemia, of which 12 (3%) had transient hypocalcemia, and 8 (2%) had permanent hypocalcemia. Postoperative hypocalcemia was detected in 9 (17.6%) patients the first group, 8 (2.4%) patients in the second group, and 3 (18.8%) patients of the third group. Patients hypocalcemia was characterized based on the types of underwent operations as follows: in 14 (5.3%; p 0.05) patients after total thyroidectomy, in 1 (3.2%) patient after close to total thyroidectomy, in 1 (16.7%) patient after total thyroidectomy with central lymphatic dissection, in 1 (20%) patient after total thyroidectomy with central and lateral lymphatic dissection, in 3 (18.8%) patients after repeated surgery. Postoperative hypocalcemia was identified in 5 of 44 patients of the second group with thyroid carcinoma, as well as in 1 patient of the third group with the same pathology (p=0.246).

Conclusion. Incidence of hypocalcemia was more frequent after surgery for hyperthyroidism, especially after total thyroidectomy; in 40% of cases, transient hypocalcemia was identified in patients with autotransplantation of the parathyroid gland after an accidental parathyroidectomy.
Features of mental disorders and their correction in patients with cardiac pathology
Authors: Zhidyaevskj A G , Mendelevich V D , Galyautdinov G S , Ibragimova K R , Zakirova E B
Published: April 2020

In everyday practice, the doctor rarely encounters only one specific disease, more often a patient with comorbid pathology comes to him. Such a group of concomitant diseases are mental disorders. Their prevalence in cardiology practice reaches 80%. Mood affective, anxiety and somatization disorders, as well as cognitive impairment are observed most often. The review looked at mental disorders that occur in cardiac diseases with the highest number of deaths, such as coronary heart disease, including myocardial infarction and cardiac arrhythmias, arterial hypertension and cerebrovascular diseases. Including attention is paid to the senile asthenia syndrome, which is accompanied by cognitive impairment, loss of previous vital interests and depression. The review highlights the questions of regular and adequate psychopharmacotherapy of cardiovascular diseases, which leads to a statistically significant decrease in the frequency of their exacerbations, which reduces the number of doctors who come to see for somatogenic symptoms, and also allows to improve the prognosis of the underlying disease and significantly reduce mortality. It was observed that the doctor should take into account the fact that modern cardiological preparations have effects that can cause side effects in the form of mental disorders when choosing a therapy. Understanding the processes of formation and occurrence of mental diseases in a patient with cardiovascular pathology, as well as methods for their correction, can increase the effectiveness of the therapy and improve the prognosis of the underlying disease.
Indicators of potentially preventable hospitalizations as a tool for improving the quality of care in cardiovascular diseases
Authors: Khafisianova R Kh , Burykin I M , Aleeva G N
Published: April 2020

Aim. To assess the possibility of using indicators of potentially preventable hospitalizations of cardiovascular diseases to assess the quality of medical care.
Methods. Indicators of quality of cardiovascular disease treatment were formed based on the analysis of literature, current clinical recommendations and the structure of potentially preventable hospitalizations in the districts and cities of the Republic of Tatarstan. The proposed indicators were studied in the districts of the Republic of Tatarstan in 20112015.
Results. It is revealed that the distribution of indicator values in the regions of the Republic of Tatarstan differs from normal and is characterized by high variation. Median, minimum and maximum of hospitalization levels for hypertension in 2015 were 8.4, 1.3 and 26.8 respectively; unstable angina, myocardial infarction 2.2, 0.02 and 8.6. Indicators for hospitalization due to stable angina, chronic ischemic heart disease also had a high level of variation (6.3, 0.2 and 17.4). As criteria for quality and optimal use of resources, it is proposed to use nonparametric estimates, one of which is the upper quartile. According to this study, in 2015, upper quartile for hypertension was 11.2; for unstable stenocardia, myocardial infarction 3.4; for stable angina, chronic ischemic heart disease 8.6.
Conclusion. The results of this study prove that indicators of potentially preventable hospitalizations may be part of a comprehensive assessment of the quality of care.
Percutaneous puncture nephrostomy on the back of a patient with an external fixation apparatus on the bones of the pelvis following a road traffic accident
Authors: Abdurakhmanov R A
Published: April 2020

The article presents a rare clinical case of renal colic with a stone in the lower third of the ureter in the patient after a traffic accident with an external fixation device on the pelvic bones. A 41-year-old patient was hospitalized to the emergency urology department of the City Hospital No. 5 of Naberezhnye Chelny in 2019 with renal colic on the right. An ultrasound revealed right pelvocaliectasis of kidney. Pelvic survey (urogram) shows the shadow (9 mm in diameter) suspicious for renal calculus in the projection of the lower third of the right ureter. The pain was not relieved by analgesics. It was unsuccessfully attempted to stent the right ureter due to insurmountable obstacle at a distance of 4 cm from the ureteral orifice. Due to technical complexity (laying the patient in a lithotomy position and on the stomach or side was impossible due to a possible breakdown of the external fixation apparatus on the pelvic bones) percutaneous puncture nephrostomy was performed under ultrasound control in the supine position according to emergency indications. The pain was relieved. The patient was discharged home. After one month, the external fixation device for the pelvic bones was removed. The patient was hospitalized again. Ureteroscopy and contact ureterolithotripsy on the right ureter were performed routinely. Nephrostomy was removed. The patient recovered. The described case is of clinical interest as a rare combination of renal colic and the presence of an external fixation apparatus on the bones of the pelvis, which causes additional difficulties for the drainage of the urinary tract. Percutaneous puncture nephrostomy on the back with a roller in the ipsilateral kidney is a good alternative for urologists when to lay the patient on the stomach or side is impossible.
Las políticas de género durante la presidencia de Cristina Fernández de Kirchner en Argentina (2007–2015)
Authors: Lisińska Magdalena
Published: April 2020

El objetivo principal del presente artículo es discutir las políticas de género –propuestas y agendas, legislación e iniciativas políticas durante la presidencia de Cristina Fernández de Kirchner en Argentina (2007–2015). Primero, analizo los éxitos de la presidencia de Cristina Fernández –en la legislación y en las cuestiones de la violencia de género. Luego, presento los problemas y las derrotas de la agenda kirchnerista en el ámbito de género. En la conclusión, resumo los argumentos presentados en el artículo y considero si la presidencia de Cristina Fernández de Kirchner puede ser identificada como un paso adelante en materia de la igualdad de géneros, los derechos igualitarios y el empoderamiento de las mujeres en Argentina.