bluuebunny/crossref_metadata_2025 huggingface dataset:
Estimation of Water Stress in Guinea and Sudano-Sahelian Ecological Zones of Nigeria Under Climate Change and Population Growth
Authors: A. C Salihu , A Abdulkadir , G. N Nsofor , M. Y Otache
Published: April 2023

Climate change and population growth are seen to be the major factors that will shape the pattern of per capita water up to the end of 21st century. The study aimed to project water stress condition in Guinea and Sudano-Sahelian ecological zones of Nigeria under the impacts of climate change and population growth. Firstly, annual water yield was generated using KNMI climate explorer for (2019-2048), (2049-2078) and (2079-2100) under three CO2 emission trajectories. Secondly, population was projected using the Nigeria’s average growth rate of 2.6%. Thirdly, the per capita water was analysed based on water stress index. Mann-Kendal statistical test was used to analyses trends in water stress at 0.05 significant levels. Result demonstrated that the Guinea and Sudano-Sahelian ecological zones of Nigeria will experience significant positive trend in water stress with respect to climate change impact for mid and long-term periods whereas no significant trend under the short-term projection. However, regional trend analysis under the influence of population growth at constant climate observed that there were significant positive trends in water stress for the three projected periods. More so, the same positive trends were obtained under the combined impacts of climate change and population growth in Guinea and Sudano-Sahelian ecological zones of Nigeria. This implies that future water scarcity is imminent and will primarily cause by population growth and secondarily by climate change in the area. The results can act as guidelines for strategic planning for adaptive and mitigation measures to water stress as envisaged by the projection.
Development Methodology of a Human-Machine Interface in the System Supporting the Operator of Industrial Facilities Acting in the Emergencies
Authors: Uali A.B. , Naukenova A.S. , Korsun O.N. , Tulekbaeva A.K. , Glukhova E.D. , Glukhov M.A.
Published: April 2023

The paper proposes methodological approaches to development of a human-machine interface for the specialized software supporting operator activities of industrial facilities in emergencies. As an example, development of a system is considered to support activities of the oil refinery operators in eliminating various failures and their consequences in accordance with the adopted regulations of the accident elimination plan. Features of the operator actions in the emergency were analyzed, and requirements for the operator support program interface were formulated. The proposed approach is based on introduction of design patterns for human-machine interfaces in the safety-critical systems. Main patterns were analyzed, and recommendations were given on the use of specific patterns in creating a software interface to support the operator actions. Results of the experimental study of possibilities of the proposed software practical application are presented showing significant reduction in the time spent by the operator on actions to execute the emergency response plan requirements and decrease the number of errors. This confirms effectiveness of the developed methodology in practice. As the area for further improvement of the industrial facilities operator actions, it is advisable to consider methods for estimating the operator state according to the data obtained from heterogeneous information channels including speech, analysis of the number of blinks, evaluation of emotions, analysis of the head tilt, direction of gaze and others using the convolutional neural networks of deep learning
En busca del paraíso perdido
Authors: Niño de Guzmán Guillermo
Published: April 2023

Es probable que el nombre de Edgardo Rivera Martínez no suene muy familiar al gran público, pero para la gente del oficio y aquellos lectores acuciosos no es un desconocido. Escritor que ha preferido mantener una existencia discreta, alejado de los vaivenes del movimiento literario local, Rivera Martínez ha ido edificando pacientemente su universo literario, casi con pudor, a contrapelo de modas y corrientes.
Does the Insulin Pump Improve Satisfaction and Glycaemic Control in Moroccan Patients with Type 1 Diabetes?
Authors: Messaoudi Najoua , Tahri Abir , Assarar Imane , Bouichrat Nisrine , Derkaoui Nada , Bouazzaoui Mohammed Amine , Rouf Siham , Abda Naima , Latrech Hanane
Published: April 2023

Introduction: Insulin pump therapy is recommended more and more to achieve and maintain optimal glycaemic control in patients with type 1 diabetes mellitus. The objective of our study was to evaluate the satisfaction of patients using insulin pump therapy and to determine its
effectiveness in improving metabolic control in type 1 diabetic patients. Patients-Methods: This is a retrospective, descriptive and analytical study including 20 type 1 diabetic patients treated by insulin pump, between 2017 and 2021. All patients received a clinical evaluation, analysis
of capillary blood glucose monitoring and a dosage of HbA1c at the time of the start of insulin pump and during the evolution. Insulin pump satisfaction was assessed using the Diabetes Treatment Satisfaction Questionnaire (DTSQ). Statistical analysis was performed by SPSS version-21. Results:
The mean age of the patients was 16,8 ± 8,1 years with a sex ratio (M/F) of 0,42. Thirty per-cent were children. The mean duration of diabetes was 5,8 ± 4,8 years. Seventy-five per-cent of patients practiced functional insulin therapy. The indications for insulin pump treatment
were mainly hypoglycaemia and instable diabetes. During follow-up, we found a statistically significant decrease in insulin requirements, improvement in mean HbA1c and maintenance of glycaemic control during follow-up, with a marked reduction in the number of hypoglycaemia events per week.
The overall satisfaction score was calculated at 34,6 ± 2,5 out of 36 with a decrease in the score for perception of hyperglycaemia or hypoglycaemia. Conclusion: Insulin pump therapy appears to be reliable and effective when used appropriately, combined with appropriate therapeutic
education and glycaemic monitoring to maintain long-term glycaemic control and improved quality of life.
Peramalan curah hujan di Provinsi Aceh menggunakan metode Box-Jenkins
Authors: Nurhafifah Nurhafifah , Patriardian Ferdy , Hidayati Alfy , Alzahira Ratu Rahil , Tasyant Deva Jhuandra , Anwar Samsul
Published: April 2023

Floods are one of the natural disasters that frequently occur in Indonesia, including in Aceh Province. Floods primarily occur when rainfall is intense, mainly in the rainy season. Flood disaster management in Aceh Province is still not optimal, so efforts are required to minimize the negative effects of the flood disaster. One of the efforts that can be done is to predict the rainfall that may occur in the future. This study aims to predict rainfall in Aceh Province in 2022 and 2023. The data employed are monthly rainfall data in Aceh Province from 2014 to 2021. The forecasting method employed to predict rainfall is the Autoregressive Moving Average (ARMA) model. Forecasting results using the ARMA (8,6) model show that rainfall in Aceh Province in 2022 and 2023 are predicted to tend to be intense in March, April, May, September, October and November. The Aceh government together with the district/city governments need to prepare anticipatory steps, for example by cleaning water flows like ditches and rivers and socializing about the dangers of flooding and its causes, especially for people living in watersheds. These actions are expected to minimize the potential for flooding in Aceh Province in the future, especially when rainfall is predicted to be intense.

Keywords:Aceh Province, box-jenkins, flood, forecasting, rainfallMSC2020:62M10
Effect of pilates training on pain and disability in patients with chronic low back pain: a systematic review and meta-analysis based on randomized controlled trials
Authors: Huang Junzhen , Park Hun-Young
Published: April 2023

[Purpose] This systematic review and meta-analysis study evaluated the effects of Pilates on pain and disability in patients with chronic low back pain.[Methods] Six electronic databases were searched between January 2012 and December 2022. From these databases, only randomized controlled trials were selected. The criteria for assessing methodological quality using the PEDro scale were selected. The risk of bias was assessed using the Cochrane Risk of Bias Tool RoB 2.0. Additionally, the primary outcomes were pain and disability in this analysis.[Results] The corresponding results confirmed that Pilates training led to a significant improvement in pain (Visual Analog Scale: weighted mean difference = -29.38, 95% confidence interval, -33.24 to -25.52, I² value = 56.70%; Pain Numerical Rating Scale: weighted mean difference = -2.12, 95% confidence interval, -2.54 to -1.69, I² value = 0.00%) and disability (Roland– Morris Disability Index: weighted mean difference = -4.73, 95% confidence interval, -5.45 to -4.01, I² value = 41.79%). Six months after completion of Pilates training, the improvement in pain (Pain Numerical Rating Scale: weighted mean difference = -1.67, 95% confidence interval, -2.03 to -1.32, I² value = 0.00%) and disability (Roland–Morris Disability Index: weighted mean difference = -4.24, 95% confidence interval, -5.39 to -3.09, I² value = 52.79%) was maintained.[Conclusion] Pilates training may be an effective strategy to improve pain and disability in patients with chronic low back pain.
A scoping review of voluntary gait adaptability tasks requiring cognitive demands in older adults
Authors: Kim Kyungwan , Vinent Marie , Deller Lena , Zijlstra Wiebren
Published: April 2023

[Purpose] Voluntary gait adaptability is a complex construct that requires cognitive demands and dynamic balance control; it also has implications for the daily lives of older adults. This ability has been extensively studied, however, a comprehensive overview of appropriate tasks for measuring voluntary gait adaptability in older adults is lacking. Our scoping review aimed to identify existing voluntary gait adaptability tasks for older adults, summarize the specific methodological features requiring cognitive demands found in previous studies, and categorize these tasks according to experimental procedure and setup.[Methods] A comprehensive literature search was performed using six databases (PubMed, SPORTDiscus, Web of Science, CINAHL, MEDLINE, and Embase). This included studies that investigated voluntary gait adaptability in older adults (≥ 65 years old) with and without neurological disorders, with a focus on experimental tasks requiring cognitive function (e.g., response to visual or auditive stimuli) while walking.[Results] Sixteen studies were included; most involved visual stimuli, such as obstacles, stairs, or colored cues, and few required auditory stimuli. The studies were categorized according to the experimental procedure, for example, ascent/descent of obstacles (n = 3), inconsistent surfaces (n = 1), lateral gait adjustment (n = 4), obstacle avoidance (n = 6), and stepping tasks (n = 2), as well as experimental setup, including instrumented treadmills (n = 3), stairs (n = 3), and walkways (n = 10).[Conclusion] The results show wide heterogeneity between studies regarding experimental procedures and setup. Our scoping review highlights the need for additional experimental studies and systematic reviews on voluntary gait adaptability in older adults.
Comparison of energy consumption and excess post-exercise oxygen consumption according to Taekwondo Taegeuk Poomsae performance in Taekwondo players
Authors: Jung Won-Sang , Sun Yerin , Park Hun-Young , Kim Sung-Woo , Jung Hoeryong , Park Sin-Ae , Kim Jisu , Lim Kiwon
Published: April 2023

[Purpose] We compared and analyzed energy consumption and excess post-exercise oxygen consumption (EPOC) following Taekwondo Taegeuk Poomsae performances.[Methods] Forty-two healthy men who could perform Taegeuk Poomsae 1–8 Jangs were enrolled in this study. To reduce the impact of Poomsae, a random cross-design was used. The washout time was set to at least three days. Oxygen consumption (VO2) was monitored after performing each Poomsae until a reference line was resumed. Each Taegeuk Poomsae was performed at a speed of 60 bpm.[Results] There was no significant difference in VO2, carbon dioxide excretion, and heart rate after performing the Taegeuk Poomsae once; however, all variables increased significantly in combined results of EPOC metabolism (F<45.646, p<0.001, and ɳ2<0.527). Taegeuk 8 Jang had the highest levels of all the factors. There were noticeable variations in the oxidation of fat and carbohydrates throughout the Taegeuk Poomsae (F<9.250, p<0.001, ɳ2<0.184). Taegeuk 8 Jang demonstrated the greatest rate of carbohydrate oxidation, and 4–8 Jangs demonstrated much greater rates of fatty acid oxidation. Compared to 1 Jang, the energy consumption showed significant differences in all the variables and peaked in Taegeuk 8 Jang.[Conclusion] The energy consumption during the Poomsae performances was the same. When the EPOC metabolism was coupled, it was evident that more energy was substantially used in each chapter of Poomsae. Consequently, it was determined that when performing Poomsae, not only should energy metabolism during exercise be taken into account but also EPOC metabolism, which can increase by 10-fold.
Comparison of three type of muscle glycogen loading interventions using a very-high-carbohydrate diet in an elite male racewalker: a case report
Authors: Kondo Emi , Takai Eri , Sagayama Hiroyuki , Takahashi Hideyuki
Published: April 2023

[Purpose] Muscle glycogen storage before a race is necessary for endurance athletes to achieve the best performance. Generally, the recommended carbohydrate intake for preparation over 90 min of the race is 10–12 g·kg--1·day--1. However, it remains unclear whether an elite athlete with an already high-carbohydrate diet can further increase muscle glycogen through a very-high-carbohydrate intake. Therefore, we compared the effects of three types of glycogen loading in a 28-year-old male athlete who belongs to the top 50 racewalkers in the world, consuming a daily energy intake of 4507 kcal and a carbohydrate intake of 12.7 g·kg--1·day--1.[Methods] The racewalker consumed very-high-carbohydrate diets three times for 2 days each, 13.7 g·kg--1·day--1 for trial 1, 13.9 g·kg--1·day--1 for trial 2, and 15.9 g·kg--1·day-1 for trial 3. Muscle glycogen concentrations in the anterior (vastus lateralis and vastus intermedius) and posterior thighs (semimembranosus, semitendinosus, and biceps femoris) were measured using carbon-13 magnetic resonance spectroscopy.[Results] Muscle glycogen concentrations in both the anterior and posterior thighs increased in all trials, particularly in trial 3. Body mass also increased by 1.5 kg in trials 1 and 2 and by 1.8 kg in trial 3 before and after the trials. The participant felt satiated throughout the day and experienced stomach discomfort during trial 3.[Conclusion] We found that a 2-day very-high-carbohydrate diet and tapering of training could further increase the muscle glycogen concentration in athletes. However, we speculated that 15.9 g·kg--1·day--1 carbohy
Motivating housekeeping staff in the lodging industry in Jordan
Authors: Ann Saehya , A. A. Hallab Zaher , Choi Hyunsuk , Al Majthoub Umaima
Published: April 2023

Purpose – The objective of this research study is to examine the complicated relationship between work motivation, job satisfaction, job dissatisfaction, and turnover intention of the housekeeping staff in selected four and five-star hotel properties in Jordan by using Herzberg’s Two-Factor theory. Design – A survey design was implemented in this research study. The sample for this research study consists of individuals working in the housekeeping departments of four and five star international hotels in Jordan. Methodology – Cluster analysis, correlation, and t-test were utilized for data analysis. The two-step clusters method was used to cluster groups based on the mean values of job dissatisfaction, as it is a unique concept that explains Herzberg’s Two-Factor Theory and also the work-related behaviour of employees. Approach – The validity of Herzberg’s Two-Factor Theory will be examined as well as examining the complicated relationship among work motivation, job satisfaction, job dissatisfaction, and turnover intention. Findings – The results of this study revealed that there is no relationship between job dissatisfaction of housekeeping staff and job satisfaction, and between job dissatisfaction and job motivation. However, there was a positive relationship between their job satisfaction and work motivation and also between their job dissatisfaction and turnover intention. No relationship was found between their work motivation and turnover intention and between their job satisfaction and turnover intention. Among all fourteen motivational factors, work itself (4.25 out of 5.00) and achievement (4.24 out of 5.00) were ranked at the top, which is consistent with Herzberg’s findings. Salary was the least satisfied/preferred factor in this study. Originality of the research – Having a separate job dissatisfaction construct in a research study is a very unique concept that Herzberg’s Two-Factor Theory (1959) developed and which also contributes to the uniqueness and originality of this study.
Mapping the research trends on social media in the hospitality sector from 2010 to 2020
Authors: Kim Eunjung , Best Alexander Rolfe , Choi Kijung
Published: April 2023

Purpose - This study undertakes a systematic review of the literature to gain insight into existing studies on hospitality in social media and provide an update on current trends and themes in scholarship. Design - This study employs the systematic literature review to identify, evaluate, and synthesize the existing literature. Methodology - A total of 165 papers published between 2010–2020 were examined using content analysis and Leximancer. Approach - This review uses a hybrid review structure that incorporates structured reviews and narrative elements supported by Leximancer analysis. Findings - The review highlights the theories and methods used, research fields and perspectives, and key research topics in the hospitality industry, showing a lack of engagement with theories, the use of a dominant theoretical approach (eWOM), and the use of quantitative research methods primarily to analyze content data. Changes in research trends are evident to keep pace with increasing social media data and respond to the needs of different industries. Originality - This study contributes by also identifying several research gaps and provide future scholarly endeavors.
Employee experience journey mapping: a new approach to attracting talent in the tourism sector in the shadows of covid-19
Authors: Horváth Viola , Kenesei Zsófia
Published: April 2023

Purpose – While customer experience management has become an essential practice for service businesses, employee experience management is a less frequently used tool. This research aims to illustrate how the customer experience mapping approach can be applied as a strategic part of employee experience planning, taking into account tourism-specific HR challenges. Design – Despite the increasing attention given to employee experience in academia, there is a lack of research extending journey mapping to employees and a clear understanding and implementation of the concept in relation to hospitality employment. Methodology – The study includes step-by-step instructions for creating an Employee Experience Journey Map. The action research project is based on interviews with the manager of a 5-star hotel ( HR ) in Budapest. During the joint work with the hotel, the manager gave iterative feedback, so that the Journey Map was continuously improved and completed. Approach – The application of the Employee Experience Journey Mapping concept includes the identification of touch points and critical ‘pain points” and the development of proposed solutions. Findings – The creation of an employee journey map can help determine the steps necessary to reduce turnover intent and improve the employee experience. Originality of the research – The results of the study show that it is important to develop an employee journey based on personas. In addition, it is beneficial for the marketing and HR departments to treat employee experience planning as a joint project.
Go Mental Healthy Mental Health Services Based on Mobile App To Address Problems In Online Learning In The Covid-19 Pandemic
Authors: Latifah Umi ba'dingatul , Hasmara Yekti Atni Dwi , Wahyu Satria Tiyas Akbar , Yulinar Mellysa Yulinar , Ananda Viona Rizqy , Harimurti Shubhi Mahmashony
Published: April 2023

During the Covid-19 pandemic, SMA Negeri 1 Cangkringan was one of the schools that implemented online learning methods. However, in practice, there are many obstacles experienced by students such as students feeling heavy and difficulty understanding the material, piling up assignments received by students, the emergence of fear in students about their academic progress, a sense of failure in achieving the expected targets, pressure to be able to learn independently, demands high concentration in paying attention to the teacher's explanation during the learning process which is often constrained by signals so that the teacher's voice is not heard by students, tired and worried about piling up assignments, pressure from parents, and students are not used to the assignment deadline. This condition makes students stressed with their academic life. Therefore, the Gotalty application was developed as a medium for educators to identify problems in online learning faced by students and assist students in maintaining a balance between psychological conditions and academic conditions during the learning process. The program implementation method is carried out by applying the PDCA method (Plan, Do, Check, and Action). The results obtained based on the program that has been carried out, namely the Gotalty application can help relieve anxiety about the problems experienced by students during online learning, and increase students' knowledge of mental health which shows that the psychoeducation process has been successfully carried out, and increases awareness of mental health. Very helpful features for program partners are motivational videos and psychology articles. This is evidenced by the results of the pretest and post-test. In addition, this program also produces outputs in the form of program implementation guidebooks, partner pocketbooks, and program implementation videos.
Development of Student Worksheet with an Ethnoscience Approach to Wati Plants Through Liveworksheet Applications
Authors: Sahnia Rumadan Nia , Asmaningrum Henie Poerwandar , Bela Sumanik Novike
Published: April 2023

This study aims to develop the student worksheet on Addictive Substances material with the Wati Plant ethnoscience approach through the Liveworksheet application that is feasible in terms of validity and practicality. This type of research is R&D research using the ADDIE model, namely: Analyze,  Design, Development, Implementation, and Evaluation. However, this research is limited to the third stage, namely the Development stage. The research subjects were one material expert, one media expert, one practitioner, and ten students of the  Chemistry Education Department, Musamus University. The instruments used in data collection were interview guidelines and questionnaires. The results showed that the student worksheet on Addictive Substances material with the Wati Plant ethnoscience approach through the Liveworksheet application got a percentage of 94% at the 6th meeting and 97% at the 7th meeting from material experts, 95% at meetings 6 and 7 from media experts, 84% at the 6th meeting and 86% at the 7th meeting of practitioner responses and 90% at the 6th meeting and 88% at the 7th meeting of student responses. Based on the results of these studies, it can be concluded that the student worksheet on Addictive Substances material with the Wati Plant ethnoscience approach through the Liveworksheet application is feasible in terms of validity and practicality aspects
Preliminary Study on the Development of Project Based Learning Inorganic Chemistry Practical Instructions
Authors: Ad'hiya Eka , Haryani Maefa Eka , Edi Rodi , W K Anom
Published: April 2023

This study aims to conduct a preliminary study in developing project-based learning practicum instructions in Inorganic Chemistry courses. This study uses a survey method, where data is obtained by conducting a survey through the Google form platform. Participants in this study were 41 students who took inorganic chemistry courses at the chemistry education study program at Sriwijaya University. The results of this study indicate that it is necessary to develop project-based learning practicum instructions for inorganic chemistry, as teaching materials in inorganic chemistry courses that apply project-based learning models in the current new normal era. The characteristics of students show that students feel happy, more motivated and feel more creative when participating in project-based learning.
Efektivitas Taman Kota Madiun dalam Memenuhi Kebutuhan Ruang Publik dari Perspektif Pengunjung
Authors: Hapsari Shabrina , Rini Erma Fitria , Rahayu Murtanti Jani
Published: April 2023

Taman kota merupakan ruang publik yang tersedia di kota guna memenuhi kebutuhan masyarakat untuk beraktivitas, beristirahat, dan berwisata. Kota Madiun sebagai pusat pengembangan wilayah di Provinsi Jawa Timur bagian barat menjadi magnet bagi kabupaten di sekitarnya sehingga meningkatkan aktivitas di Kota Madiun. Meningkatnya aktivitas kota membuat tingginya mobilitas penduduk sehingga keberadaan taman kota penting untuk mengimbanginya. Dalam mencapai perannya, taman kota tidak hanya dilihat dari keberadaannya, tetapi juga bagaimana taman kota tersebut mampu memenuhi kebutuhan pengunjung. Tujuan dari penelitian ini adalah untuk mengetahui tingkat efektivitas taman-taman di Kota Madiun dilihat dari kebutuhan pengunjung terhadap  ruang publik. Penelitian ini merupakan penelitian kuantitatif yang menggunakan pendekatan deduktif. Teknik pengumpulan data dilakukan dengan menggunakan kuesioner, observasi, dan studi literatur. Penelitian ini menggunakan teknik analisis skoring dengan pengukuran Skala Guttman. Efektivitas taman kota dilihat dari kebutuhan pengunjung taman kota, yaitu kenyamanan, keamanan, aktivitas, dan aksesibilitas. Berdasarkan analisis terhadap keempat kebutuhan pengunjung di ruang publik tersebut, keamanan merupakan kebutuhan yang terpenuhi di setiap taman kota, sedangkan ketiga kebutuhan lain belum terpenuhi secara keseluruhan di setiap taman kota. Tingkat efektivitas taman kota dibagi ke dalam tiga kategori, yaitu efektif, cukup efektif, dan tidak efektif. Berdasarkan hasil analisis, tujuh taman kota di Kota Madiun termasuk dalam kategori efektif dan satu taman kota masuk dalam kategori cukup efektif.
Karakteristik Aktivitas Perdagangan dan Jasa sebagai Aktivitas Pendukung Perguruan Tinggi: Studi Kasus Kecamatan Kartasura dan Kecamatan Laweyan
Authors: Dikta Talitha Benny , Mukaromah Hakimatul , Rahayu Paramita
Published: April 2023

Kecamatan Kartasura, Kabupaten Sukoharjo memiliki arahan pengembangan pendidikan serta perdagangan dan jasa berdasarkan RTRW Kabupaten Sukoharjo Tahun 2011-2031. Pengembangan pendidikan dapat ditinjau dari keberadaan kawasan pendidikan Desa Gonilan, Desa Pabelan, Desa Makamhaji, Kecamatan Kartasura, sertaKelurahan Karangasem, Kecamatan Laweyan, Kota Surakarta yang berbatasan langsung dengan Kecamatan Kartasura dimanaterdapat dua perguruan tinggi di dalamnya. Penelitian ini bertujuan mengetahui perkembangan aktivitas perdagangan dan jasa di kawasan perguruan tinggi. Hal ini dikarenakan perkembangan aktivitas pendidikan memberikan peluang peningkatan perekonomian dan perubahan lahan nonterbangun menjadi terbangun. Penelitian dilakukan dengan pendekatan deduktif dan menggunakan jenis penelitian kuantitatif dengan teknik analisis deskriptif spasial untuk mengetahui perubahan penggunaan lahan yang terjadi serta deskriptif statistik untuk mengetahui persentase peningkatan aktivitas sejak tahun 2011. Pengumpulan data menggunakan teknik pengumpulan data primer melalui observasi dan kuesioner kepada pelaku usaha, serta data sekunder melalui dokumen dan citra satelit. Dari hasil penelitian, didapatkan bahwa aktivitas perguruan tinggi berperan penting dalam perkembangan aktivitas perdagangan dan jasa selama 2011-2022. Peningkatan jumlah mahasiswa sebesar 29% berpengaruh terhadap persebaran dan luas sarana perguruan tinggi sebesar 42%. Aktivitas perguruan tinggi memberikan peluang peningkatan perekonomian 45% yang sebagian besar dimanfaatkan masyarakat sekitar. Perkembangan aktivitas perguruan tinggi dan peluang perekonomian pada kawasan berdampak terhadap peningkatan luas sarana perdagangan dan jasa sebesar 52%.
Dukungan Kinerja Pengelolaan Sampah terhadap Kesesuaian Penerapan Konsep Keberlanjutan Lingkungan di Kota Mataram
Authors: Al-Giffari Muh. Haikal , Yudana Galing , Suminar Lintang
Published: April 2023

Kota kini bukan sekedar tempat bermukim, melainkan juga sebagai pusat pelayanan yang harus dapat melayani masyarakat kota dan daerah sekitarnya. Dalam perkembangannya, suatu kota tidak terlepas dari permasalahan dan hambatan seperti kebutuhan terhadap pembangunan, menurunnya ketersediaan sumber daya, kurangnya fasilitas umum, dan permasalahan lingkungan. Salah satu permasalahan yang kerap hadir di perkotaan dan belum mampu diatasi dengan maksimal adalah permasalahan terkait pengelolaan sampah. Sampah yang tidak dikelola dengan baik dapat menyebabkan permasalahan bagi perkembangan suatu kota. Kota sebagai pusat pelayanan berpotensi meningkatkan pertumbuhan penduduk dan kegiatan di dalamnya, sehingga secara tidak langsung produksi sampah yang dihasilkan akan meningkat. Oleh karena itu, diperlukan adanya pengelolaan sampah yang memadai sehingga dapat mempermudah perkembangan suatu kota kedepannya. Kota Mataram merupakan Ibukota Provinsi Nusa Tenggara Barat dan menjadi salah satu pusat pelayanan yang ada. Pada tahun 2021, Kota Mataram memiliki  jumlah penduduk sebanyak 495.681 jiwa dengan luas wilayah sebesar 6.130 Ha. Dengan jumlah penduduk 495.681 jiwa, timbulan sampah di Kota Mataram cukup tinggi sehingga perlu adanya pengelolaan sampah yang memadai dalam mengurangi dan menangani sampah serta mengurangi dampak negatif dari produksi sampah yang ada. Berdasarkan kondisi tersebut, penelitian ini mengkaji kesesuaian kinerja pengelolaan sampah dalam mendukung penerapan konsep keberlanjutan lingkungan di Kota Mataram. Metode penelitian yang digunakan pada penelitian ini adalah pendekatan kuantitatif dengan metode deskriptif. Pendekatan kuantitatif dilakukan melalui perhitungan skoring pada tiap indikator dalam variabel yang akan menentukan tingkat klasifikasi kesesuaian kinerja pengelolaan sampah dalam mendukung penerapan konsep keberlanjutan lingkungan di Kota Mataram. Terdapat enam komponen yang  dikaji dalam penelitian ini, yaitu aspek teknis, aspek kelembagaan, aspek pembiayaan, aspek kebijakan, aspek peran masyarakat, dan target kinerja pengelolaan sampah. Berdasarkan hasil, kinerja pengelolaan sampah di Kota Mataram berada pada tingkatan klasifikasi kurang sesuai dalam mendukung penerapan konsep keberlanjutan lingkungan.
Pengaruh Life Course Event terhadap Housing Mobility
Authors: Aulia Silka Azzahra Shafa , Adianto Joko
Published: April 2023

Dari hasil riset yang dilakukan oleh Alvara Research Center, diketahui bahwa generasi milenial mendominasi populasi di Indonesia pada tahun 2020 dengan porsi sekitar 34 persen dan diikuti 20 persen generasi X. Milenial lebih memilih tinggal bersama orang tuanya, sehingga mengarah pada keterlambatan kepemilikan rumah. Sebaliknya, Gen X (lahir 1965 hingga 1980) yang dicirikan sebagai pemecah masalah yang baik dan logis memiliki karakteristik dan preferensi kepemilikan rumah yang berbeda daripada generasi milenial. Hal ini menjadikan menarik untuk membahas perjalanan perpindahan rumah para Gen X sebelum akhirnya memiliki rumah kepemilikan pribadi. Penelitian ini bertujuan untuk mengetahui hubungan perjalanan hidup (life course) terhadap perpindahan rumah (housing mobility) yang dialami oleh Gen X. Perjalanan hidup (life course event) diartikan sebagai pendekatan untuk menyelidiki perubahan lingkungan individu dan implikasi perkembangannya berdasarkan usia dalam matriks hubungan sosial dan proses perkembangan. Mobilitas perumahan (housing mobility) diartikan sebagai kejadian berpindah–pindah suatu rumah tangga dalam proses menempati tempat tinggal secara pribadi. Teknik pengumpulan data dilakukan dengan wawancara tidak terstruktur. Narasi yang disusun memungkinkan untuk memeriksa interkoneksi banyak elemen perjalanan hidup yang kompleks. Wawancara dilakukan pada bulan Mei 2022 melalui sambungan telepon. Hasil studi ini mengungkapkan sifat mobilitas perumahan serta kemungkinan menghadapi perubahan arah kehidupan tergantung pada tahapan perjalanan hidup rumah tangga tersebut. Maka dari itu, model perilaku mobilitas perumahan harus memasukkan penyesuaian perumahan dan perubahan dalam perjalanan hidup rumah tangga.
Estrategia comercial en la exportación de la empresa Productos Peruanos, Lima, 2021
Authors:   , Jesus Sucasaire Alexandra Dalendy
Published: April 2023

El presente investigación tiene con el objetivo de analizar el contexto empresarial que se dedica al agro alimento con el fin de ver si existe una correlación entre la estrategia comercial y la exportación en la empresa Productos Peruanos S.A.C., considerándose importante en la actividad comercial, que se realizan a nivel de mercadeo, por la cual será de gran ayuda para las demás organizaciones el poder tener información para mantenerse vigentes en el mercado competitivo en el cual se desenvuelven diferentes rubros, ante una crisis de pandemia. Por lo tanto, la investigación presentado es de nivel correlacional, con diseño no experimental con corte trasversal, se examinó con una muestra de 25 colaboradores, se utilizó el cuestionario, el mismo que fue validado por tres expertos y se utilizó el alfa de Cronbach, dando como resultado un coeficiente de 0.77 para la estrategia comercial y 0.85 para la exportación en la breve investigación, asi mismo donde se obtuvo como resultado el valor de 0,75 de lo que llevo a concluir que hay una relación entre las variables.
Asociación entre niveles de la glicemia y la presencia de síntomas autonómicos en adultos de 30 a 69 años
Authors:   , Angeles Zurita Gabriel Giulino , Narro Fuentes Margorie Alicia
Published: April 2023

Objetivos: Determinar si mayores niveles glicemia se asocia a mayor presencia de síntomas autonómicos en adultos de 30 a 69 años. Métodos: Análisis de datos de un estudio transversal de base poblacional. La presencia de síntomas autonómicos se definió en base a la Encuesta de Síntomas Autonómicos (SAS en inglés), mientras que los niveles de glicemia fueron definidos como normal, prediabetes y diabetes mellitus tipo 2 (DM2) de acuerdo con la prueba de tolerancia oral a la glucosa. Para evaluar la asociación de interés se construyeron modelos de regresión de Poisson, con link log y varianza robusta, y de regresión lineal, y se reportaron razones de prevalencia (RP) o coeficientes, y sus respectivos intervalos de confianza al 95% (IC 95%). Resultados: Un total de 1607 personas con una edad media 48,2 años (DE: 10,6) y 810 (49,7%) mujeres fueron incluidos en el estudio. De todos los síntomas autonómicos evaluados, tener DM2 estuvo asociado con mayor probabilidad de tener disfunción eréctil (RP = 3,17; IC 95%: 1,90 – 5,28) en varones y mayor sequedad de boca y ojos (RP = 1,28; IC 95%: 1,02 – 1,61) comparado con los euglicémicos. La prediabetes no estuvo asociada a ningún síntoma autonómico. Además, aquellos con DM2 tenían 0,32 (IC 95%: 0,04 – 0,62) y 1,03 (IC 95%: 0,03 – 2,03) puntos más en la escala de síntomas autonómicos y en la escala de severidad, respectivamente, comparado con los euglicémicos. Conclusiones: La disfunción eréctil en varones y la sequedad de boca y ojos son dos de los síntomas autonómicos más comunes asociados a DM2. Nuestros resultados sugieren la evaluación periódica de la función sexual y de la humedad de los ojos en pacientes con DM2.
Comparación entre la aplicación de bupivacaína intraperitoneal al 0.5% y 0.25% para manejo de dolor postquirúrgico en perras sometidas a ovariohisterectomía en Lima-Perú
Authors:   , Perez Moreno Diego Alonso
Published: April 2023

La ovariohisterectomía es una cirugía frecuente en medicina veterinaria, con un rango de dolor moderado. El estudio evaluó los efectos analgésicos post-operatorios generados por las diferentes concentraciones de bupivacaína (0.5% y 0.25%) intraperitoneal teniendo como objetivo comparar el manejo de dolor postquirúrgico en perras sometidas a ovariohisterectomía utilizando ambas concentraciones. Se utilizaron 30 perras en 3 grupos, cada grupo recibió bupivacaína intraperitoneal a 2mg/kg antes de culminar el cierre de la incisión; el grupo A (bupivacaína 0.5% IP), grupo B (bupivacaína 0.25% IP) y grupo C (bupivacaína al 0.25% IP, Tramadol a 4mg/kg IM, Meloxicam 0.2mg/kg SC y Dipirona 25mg/kg IV). La analgesia post quirúrgica se evaluó con la escala de Glasgow modificada versión corta en 4 momentos: 0.5, 1, 2 y 3 horas. Cabe resaltar que la evaluación se realizó hasta que los pacientes empezaban a presentar signos de dolor. Se utilizó un análisis de supervivencia para evaluar si existía una diferencia estadística (p=0.0063), lo que es observado también en la curva de Kaplan-Meier. El grupo A presentó dolor a la 0.5 horas y el grupo B presentó dolor a las 2 horas. Por lo que se puede concluir que la bupivacaína aplicada a 2mg/kg al 0.25% genera un mejor manejo de dolor que al 0.5%.
Tratamiento de aguas residuales con el uso de la microalga Chlorella vulgaris para la remoción de materia orgánica
Authors:   , Aguilar Moreno Joseph Anthony
Published: April 2023

La utilización de la microalga Chlorella vulgaris son una opción ecoamigable y rentable principalmente si se integra en la depuración del agua residual empleando la materia orgánica y nutriente presente del agua como medio de cultivo. Es así, que el objetivo en este estudio fue evaluar la eficiencia de remoción de materia orgánica mediante el uso de la microalga C. vulgaris en las aguas residuales municipales del distrito de Monzón (Huánuco). Para determinar la capacidad de remoción se empleó un sistema de crecimiento de cultivo llamado “Biorreactor” por un periodo de 17 días donde el análisis físico-químico de las muestras a tratar fueron antes y después del experimento, asimismo se monitoreó diariamente el crecimiento de la microalga a través de la cuantificación de peso seco, velocidad especifica de crecimiento, productividad, temperatura, pH y las lecturas de absorbancia. El experimento contó con tres unidades experimentales sin el agua residual y tres unidades con el agua residual a una concentración de 21%. Los valores de porcentaje de remoción para el DQO, DBO, fosfato y nitrato fueron -293.0%, 41.9%, 69.13% y -107 592%, respectivamente. Donde el valor negativo del DQO se relacionó con la descomposición de las microalgas viejas a través de las bacterias y la liberación de la materia orgánica (sustancias poliméricas extracelulares ) luego que las microalgas fijaran el CO2, y para el valor negativo de nitrato se relacionó con la presencia de bacterias nitrificantes (BN). Por otra parte, los metales pesados como Ni, Cr, Pb y Cd fueron ligeramente superiores al Límite Máximo-Permisible (LMP).En conclusión, se ha demostrado que, si es posible la biorremediación de aguas residuales municipales a partir del cultivo de C. vulgaris.
The Effect of Nano Heavy Metal Oxide Particles on the Wettability of Carbonate Reservoir Rock
Authors: Pashaei Hassan , Ghaemi Ahad , Miri Rohaladin
Published: April 2023

Production of oil from carbonate rocks is very challenging due to their inherent nature, such as detection, complex wettability, pore structure, and low recovery factor. Nanoparticles (NPs) are recognized as remarkable materials for a wide range of research and commercial applications due to their physical properties and characteristics. Extensive research in recent years has shown that nanoscience can provide great potential for the development of carbonate reservoirs and enhanced oil recovery (EOR). In this study, the carbonate core plug samples were prepared from an Iranian reservoir. At first, the wettability capacity of the core samples was evaluated. This process was carried out by evaluating wettability changes using the contact angle of base fluid and nanofluid. The potential of the NPs (ZnO, TiO2, and ZrO2) to change the wettability was experimentally tested in the loading NPs from 0.01 wt% to 0.5 wt% by the contact angle method. Wettability studies have shown that nanofluids can influence wettability variability from oil-wet to water-wet quality. About 0.05 wt% of NPs was found to be the optimal concentration to affect wettability change. The same behavior was observed for all nanofluids at the same NP loading; while TiO2 showed better performance with a sharp change from an oil-wet state (θ = 151.9°) to a water-wet state (θ = 111.3°), ZnO, and ZrO2 changed wettability to a moderately-wet condition (θ = 108.6° and 118.6°, respectively) at 0.05 wt% NP loading. We conclude that TiO2-based nanofluids have great potential as EOR agents, and TiO2 is very impressive in its strong water-wettability. The highest oil recovery in the optimal amount for all three nanofluids was obtained as 35.2%, 23.2%, and 25.6%, respectively, for TiO2, ZnO, and ZrO2 nanofluids. Furthermore, we considered the effect of nanofluids on the recovery performance of the brine/oil system for carbonate core samples. The results showed that nanofluids can significantly imbibe into the core sample, and as a result, the final oil recovery is significant.
Enhanced ethanol production using hydrophobic resin detoxified two-step pre-treated Pine forest litter hydrolysate, mass balance equation generation and BOLT-ON process development supplementing molasses
Authors: Pandey Ajay Kumar , Negi Sangeeta
Published: April 2023

High ethanol demand to make up the targets of the future gradual replacement of gasoline it is essential to look for hybrid technologies using first generation and second-generation biofuel feedstock’s. The current study used a two-step sequential pre-treatment (first dilute alkali, then dilute acid) of Pine (Pinus roxburghii) forest litter (PFL), for bioethanol production. Further, the saccharification of pre-treated PFL was optimized through response surface method using Box–Behnken Design, wherein 0.558 g/g of reducing sugar was under optimized conditions: 12.5% (w/v) of biomass loading, 10 FPU of enzyme, 0.15% (w/v) of Tween-80 in 48 h. During fermentation using Saccharomyces cerevisiae NCIM 3288 strain, the ethanol titre was 22.51 g/L, which was enhanced to 27.38 g/L after detoxification of PFL hydrolysate with hydrophobic resin (XAD-4). Furthermore, the hydrolysate was supplemented with molasses (total initial sugar: 100 g/L), wherein 46.02 ± 2.08 g/L ethanol was produced with 0.482 g/g yield and 1.92 g/l/h productivity. These results, showed that BOLT-ON Technology involving integration of molasses, increases the initial sugar availability leading to enhanced ethanol production, therefore can be compatible in bio-refineries to produce high titer ethanol.
Synthesis of Cu and CuO Nanoparticles from E-waste and Evaluation of Their Antibacterial and Photocatalytic Properties
Authors: Abdelbasir Sabah M. , Rayan Diaa A. , Ismail Mahmoud M.
Published: April 2023

Waste printed circuit boards (WPCBs) contain a plethora of valuable metals, considered an attractive secondary resource. In the current research, a hydrometallurgical process combined ammonia/ ammonium chloride leaching and reduction to recover copper and its oxide (CuO) as nanosized particles from WPCBs was investigated. The results of leaching indicated that 96.7% of copper could be recovered at a temperature of 35 °C for a leaching duration of 2 h with ammonium chloride and ammonia concentration of 2 mol/L at a solid:liquid ratio of 1:10 g/cm3. The synthesized particles exhibit spherical and distorted sphere morphology with average particle size of 460 nm and 50 nm for Cu and CuO NPs, respectively. The antibacterial activity of Cu, CuO, and a (1:1) blend of both (Cu/CuO) has been examined against five different bacterial and fungal strains. The highest zone of inhibition was measured as 21.2 mm for Cu NPs toward E. coli and 16.7 mm for Cu/CuO blend toward B. cereus bacteria. The highest zone of inhibition was measured as 13 mm and 13.8 mm for Cu/CuO blend toward F. proliferatum and P. verrucosum fungi. Cu/CuO blend showed notable photocatalytic activity towards Rhodamine B dye under visible light irradiation with 96% degradation rate within 120 minutes.
METTL3-mediated m6A methylation regulates ovarian cancer progression by recruiting myeloid-derived suppressor cells
Authors: Wang Jinyong , Ling Dakai , Shi Lulin , Li Huayun , Peng Minhua , Wen Huihong , Liu  , Zhang Guangzhi , chen shanze
Published: April 2023

Background
Ovarian cancer typically develops an immunosuppressive microenvironment with excess recruitment of various leukocytes. The infiltrated leukocytes often exhibit protumor or anti-tumor activity depending on the surrounding signals in the microenvironment. Dysregulated m6A level is associated with cancer progression by influencing intrinsic oncogenic pathways in tumor cells. However, the role of m6A in regulating host immune cell function during anti-tumor immunity still needs to be fully investigated.
Methods
We firstly generated the myeloid-specific Mettl3 gene knockout mice by using the CreLoxP system in which Mettl3fl/fl mice were crossed with Lyz2-Cre +/+ mice. ID8 were injected intraperitoneally into WT and Mettl3-cKO mice used as a syngeneic mouse model for evaluation of epithelial OC growth. Next, we analyzed the compositions of different immune cell populations in the TME by flow cytometry and single cell sequenencing. Furthurmore, we investigate why Mettl3-cKO mice recruit more Gr-1+ MDSCs in the peritoneal cavity after OC cells implantation by ELISA based screening of chemokines and cytokines in peritoneal lavage and serum. Lastly, we specify the role of METTL3 in regulating IL-1β secretion and inflammasome activation in Bone marrow-derived macrophages (BMDMs) cocultured with either ID8 cell by using immunoblotting and ELISA.
Results
In this study, we aimed to investigate the role of METTL3, a catalytic subunit of the methyltransferase complex, in regulating host immune cell response against ovarian cancer. We found that ovarian cancer cell growth was enhanced in Mettl3-deficient mice. A shift of decreased M1 polarization to increased M2 polarization of macrophages during ovarian cancer progression was observed. Furthermore, Mettl3 depletion in myeloid lineage cells facilitates the recruitment of Gr-1 + MDSCs by increased secretion of CCL2 and CXCL2. Interestingly, we demonstrated that Mettl3 deficiency enhances IL-1β secretion induced by viable ID8 cells but not cell lysates independent of inflammasome activation and cell death. Therefore, in tumor-bearing mice, ovarian cancer cells trigger a slight inflammatory response with a low-to-moderate secretion of pro-inflammatory cytokines and chemokines.
Conclusion
This study provides new insights into METTL3-mediated m6A methylation in regulating host immune response against ovarian cancer.