bluuebunny/crossref_metadata_2025 huggingface dataset:
The Survey of Community Anxiety During the Emergency Care (Community Activity Restriction Enforcement) Period
Authors: Puspitaningsih Dwiharini , Laga Hadi Kusuma Yudha , Mawaddah Nurul
Published: April 2022

In the few months, increased Covid-19 cases in Indonesia forced the government to Emergency CARE (Community Activity Restriction Enforcement) program in Java-Bali. In addition to COVID-19 impact, Emergency CARE also adds anxiety to the community. This paper aims to analyze community anxiety during the Emergency CARE period. It was a descriptive-analytic study with a survey method. The variable was community anxiety during the Emergency CARE period. Sampling used non-probability sampling with convenience sampling technique with 165 respondents scattered in Java and Bali. In addition, this study used the Zung Self-Rating Anxiety Scale (ZSAS) instrument. The results showed community anxiety was mostly respondents (78%) within normal limits, 16% experienced mild, and 6% had moderate anxiety. In conclusion, there is no community anxiety during the Emergency CARE  period. However, the implementation of Emergency CARE potentially causes community anxiety because it has an average anxiety score that exceeds the minimum anxiety score based on the ZSAS instrument assessment. It is necessary to improve information, education, and communication (IEC) regarding preventing Covid-19 transmission and properly handling psychosocial problems in society to lead to a strong family during the pandemic. Furthermore, This survey could be a policy recommendation to follow-up in overcoming community psychosocial problems due to the Emergency CARE program.
Filosofía de la mente y prueba de los estados mentales: Una defensa de los criterios de “sentido común”
Authors: González Lagier Daniel
Published: April 2022

La prueba de los hechos psicológicos o estados mentales plantea dificultades de carácter ontológico (¿existen realmente hechos mentales, distintos de los hechos físicos?), epistemológico (¿cómo puedo conocer los estados mentales de los demás?) e ideológico (¿son jurídicamente relevantes?). Una parte de la doctrina y de la jurisprudencia ha dicho que, en realidad, los estados mentales no son -o no deben ser tratados como- “hechos” propiamente, por lo que no se prueban (esto es, no se demuestra que hayan ocurrido o hayan existido), sino que para el Derecho son entidades ficticias que se imputan o adscriben a partir de ciertos criterios normativos. Este escepticismo contrasta con el hecho de que todos atribuimos con frecuente éxito estados mentales a los demás y conseguimos adaptar y coordinar nuestra conducta a la de los otros gracias a esas atribuciones. Sabemos atribuir estados mentales, pero no sabemos cómo lo hacemos. En este trabajo trato  de analizar qué luz puede arrojar la filosofía de la mente (en particular, las teorías acerca del llamado “problema de las Otras Mentes”) a la prueba de los hechos psicológicos en el Derecho.
Justificación epistémica, evidencialismo robusto y prueba jurídica
Authors: Aguilera García Edgar Ramón
Published: April 2022

Entre la prueba jurídica y la epistemología puede surgir, entre otros, un tipo de vínculo semejante al que se establece entre cierto objetivo, meta o finalidad deseable y el o los medios idóneos para alcanzarlo, es decir, un vínculo de racionalidad instrumental. Esta clase de relación ha sido explícitamente sugerida por la conocida como “Tradicion Racionalista de la Prueba Jurídica”. Para dicha tradición, la relación de racionalidad instrumental en comento se obtiene, por un lado, como resultado de atribuirle a la institución jurídico-procesal de la prueba, la finalidad primordial de maximizar los episodios de coincidencia o de correspondencia entre el contenido de la premisa menor o fáctica de un silogismo judicial y la realidad (o de minimizar las ocasiones de falta de esa coincidencia) y, por otro, de considerar que el medio idóneo para lograr la maximización de la verdad (o la minimización del error) en este contexto consiste en que principalmente los legisladores y los jueces, en sus respectivas labores, se dejen guiar por los conceptos, nociones, teorías, reglas y principios provenientes justamente del terreno de la epistemología (o racionalidad empírica) general. En sintonía con esta importante influencia que la epistemología debería ejercer en el derecho y el razonamiento probatorios (así como en los desarrollos teóricos sobre estas cuestiones), me propongo a continuación dar cuenta de un debate, en mi opinión, poco explorado por la referida tradición racionalista, que se origina en las filas del denominado “evidencialismo” en epistemología (y que ha cristalizado en la propuesta de un evidencialismo más robusto), con el propósito de esbozar una visión de la prueba jurídica que podría emerger de su consideración. Ella estaría integrada por un componente aretaico (que tiene que ver con el despliegue de ciertas virtudes intelectuales), una concepción argumentativa de la prueba en el derecho y un análisis expresivista de los enunciados probatorios del tipo “está probado que ‘p’”.
Efeitos agudos do exercício contrarresistência com restrição de fluxo sanguíneo na função endotelial e agregação plaquetária
Authors: Meirelles Claudia de Mello , Fernandes Junior Marcio Lopes , Matsuura Cristiane , Gomes Paulo Sergio Chagas
Published: April 2022

Objetivo: Comparar a função endotelial e a agregação plaquetária após exercícios contrarresistência de baixa intensidade com restrição do fluxo sanguíneo (BI-RFS) ou fluxo sanguíneo livre (BI-FSLivre) e alta intensidade com fluxo sanguíneo livre (AI-FSLivre) em adultos saudáveis. Métodos: Dez homens saudáveis ​​(23 ± 3 anos) realizaram três ensaios experimentais envolvendo leg press bilateral e extensão de joelho em um delineamento cruzado randomizado: BI-RFS (3 x 15 repetições a 30% 1RM), BI- FSLivre (3 x 15 repetições a 30% 1RM) e AI-FSLivre (3 x 8 repetições a 80% 1RM). A RFS foi mantida em 50% da pressão de oclusão total individual durante as três séries, e foi liberada após o final da série 3. A dilatação fluxo-mediada da artéria braquial (DILA) foi medida com ultrassom com Doppler antes e após o exercício. O sangue foi coletado para determinar as concentrações de nitrito e a agregação plaquetária. Resultados: Nenhum dos voluntários relatou qualquer reação adversa. A ANOVA 3 x 2 com medidas repetidas em ambos os fatores (condição vs. tempo) não indicou efeitos principais ou interações significativas para DILA, diâmetro basal e de diâmetro máximo da artéria braquial, nem força de cisalhamento. Nitrito plasmático e agregação plaquetária não diferiram entre as três condições de exercício nem pré-pós exercício. Conclusão: O exercício contrarresistência de membros inferiores realizado em baixa ou alta intensidade, com ou sem RFS não afeta a DILA, os níveis de nitrito, nem a agregação plaquetária. Os achados indicam que tais condições de exercício não parecem representar risco cardiovascular do ponto de vista hemostático em adultos saudáveis.
Pemanfaatan Teknologi Informasi dan Komunikasi dalam Layanan Bimbingan dan Konseling di Sekolah : Problematika dan Solusinya
Authors: Ilfana Aulia , Herdi Herdi
Published: April 2022

This study aims to describe the benefits of information technology in Guidance and Counseling services in schools. This research method uses a literature study which contains the concepts and theories used based on the available literature, especially from articles published in various scientific journals. Furthermore, the data analysis technique used interpretive descriptive analysis. The results of this study indicate that information and communication technology is an important factor in the process of guidance and counseling services by BK teachers or school counselors. The use of information and communication technology is expected to encourage BK teachers or counselors to be more creative, innovative, varied in seeking the latest information in the service process. Technology must be used as well and optimally as possible by the guidance and counseling teacher or counselor so that the services provided can provide optimal results.
Implementasi Metode Mind Map untuk Meningkatkan Hasil Belajar Matematika Materi Bangun Ruang bagi Siswa Kelas V SDN 29 Mataram
Authors: Musniah Musniah
Published: April 2022

The purpose of this study was to improve student learning outcomes in learning mathematics on the material of building space using the mind map method for fifth grade students at SDN 29 Mataram. The research method used is a class action research model of Kemmis and Taggart with a spiral system cycle in which each cycle consists of planning, action, observation, and reflection. The subjects in this study were class V students, totaling 37 people. The research instruments are observation sheets, tests, and documentation. The data analysis technique used descriptive qualitative and quantitative analysis. The results showed that students' mathematics learning outcomes using the Mind Map method had increased. This is indicated by an increase in the average mathematics learning outcomes of class V students of 49.01%. In addition, the results of the analysis of observational data have increased from 46.7% to 86.7%.
Anemia y estado nutricional en embarazadas que acuden al puesto de salud pasaje Tinguiña Valle de Ica 2018
Authors: Valenzuela Cincia Gladys Beatriz
Published: April 2022

Objetivo: Determinar la relación que existe entre la anemia y el Estado Nutricional en embarazadas que acuden al Puesto de Salud Pasaje Tinguiña Valle Ica 2018. Materiales y Métodos: Estudio observacional transversal, que evaluó 134 gestantes atendidas de enero a diciembre del año 2018. Se aplicó la ficha de recolección de datos con las variables de interés, los datos obtenidos se ingresaron y procesaron en una matriz de SPSS versión 22. Resultados: Se encontró un 16% de anemia leve en relación con IMC Adecuado. En el primer trimestre de gestación, se encontró anemia leve en un 7% con un IMC adecuado y la media de Hb fue 11,9 gr/dL. En el tercer trimestre la anemia leve represento 8% con IMC adecuado. Al comparar la ganancia del peso durante el embarazo según el peso pre gestacional se observó una tendencia al sobrepeso y obesidad independientemente de la categoría pregestacional. Conclusiones: Encontramos que durante el embarazo la anemia se encontró presente a pesar de tener un IMC adecuado y fue ligeramente mayor en el tercer trimestre.
New perspectives on Eastern Baltic cod movement patterns from historical and contemporary tagging data
Authors: Mion M , Griffiths CA , Bartolino V , Haase S , Hilvarsson A , Hüssy K , Krüger-Johnsen M , Krumme U , Lundgreen RBC , Lövgren J , McQueen K , Plikshs M , Radtke K , Raitaniemi J , Casini M
Published: April 2022

Knowledge of the movement patterns and area utilisation of commercially important fish stocks is critical to management. The Eastern Baltic cod Gadus morhua, one of the most commercially and ecologically important stocks in the Baltic Sea, is currently one of the most severely impacted fish stocks in Europe. During the last 2 decades, this stock has experienced drastic decreases in population size, distributional range, individual growth and body condition, all of which may have affected the movements between different areas of the Baltic Sea. In this study, we investigated the seasonal movement patterns of Eastern Baltic cod by re-analysing historical tagging data collected by the countries surrounding the Baltic Sea (1955-1988) and compared historical patterns with contemporary data from a recent international tagging experiment (2016-2019). Our re-analyses of historical data showed the presence of different movement behaviours, i.e. resident or seasonally migratory, with larger distances moved by cod released in the northern and central Baltic areas compared to cod released in the southern Baltic areas. Furthermore, trends from the recent tagging experiment indicate a persistent resident strategy in the southern Baltic area. These findings present additional information on general movement patterns and area utilisation of Eastern Baltic cod that could inform future management actions and aid stock recovery.
Perifériás verőérbetegek szűrése és ellátása Magyarországon
Authors: Farkas Katalin , Kolossváry Endre
Published: April 2022

A perifériás verőérbetegség az alsó végtagi panaszok által okozott életminőség-romlás, a végtagvesztés kockázata mellett fokozott cardiovascularis rizikót hordoz. Nemzetközi epidemiológiai adatok extrapolációjára alapozva, a magyar népességben a betegség közel 600 000 embert érinthet. Az utóbbi években két tudományos kutatás kezdődött, amely 1. célul tűzte ki egy reprezentatív, magas vérnyomásban szenvedő kohorsz vizsgálata során a perifériás verőérbetegség szűrésének elemzését (ÉRV program), és amely 2. a teljes biztosított népesség adatait használva elemezte azon betegek adatait, akik alsó végtagi amputáción estek át, vagy revascularisatióban részesültek (HUNVASCDATA vizsgálat). Jelen összefoglaló tanulmány e két vizsgálat eredményeit mutatja be. Azért kiemelt a hazai adatelemzés jelentősége, mert a magyarországi érbetegellátás javulásának feltétele a hazai helyzet részletes ismerete.
A magyarországi várólista-csökkentési program orvosszakmai összetételének, igénybevételi mutatóinak és területi megoszlásának elemzése 2015–2018 időszakában
Authors: Pónusz Róbert , Boncz Imre , Kovács Dalma , Csonka Diána , Gazsó Tibor , Molics Bálint , Ludman István , Endrei Dóra
Published: April 2022

Magyarországon 2015-től kezdődően szisztematikus várólista-csökkentési program vette kezdetét („X” térítési kategória) a várakozási idő számottevő mérséklése céljából. Vizsgálatunkban a 2015–2018 közötti időszakban az „X” térítési kategóriában elszámolt esetek igénybevételi mutatóit és területi megoszlását elemeztük. Retrospektív, kvantitatív kutatásunk a Nemzeti Egészségbiztosítási Alapkezelő által biztosított adatbázison alapult, amely a várólista-csökkentési program finanszírozására 2015-ben létrehozott „X” térítési kategóriában elszámolt esetszámokat foglalta magában 2015–2018 között. Az adatbázis tartalmazta a betegek nemét és életkorát, megye szerinti lakhelyét, az ellátó intézmény megyéjének és tí­pusának megnevezését, valamint az elvégzett beavatkozásokat. A vizsgálati időszakban 27 716 esetszámot (átlagéletkor 68,05 év) számoltak el női többséggel (63,1%). Tízezer lakosra vetítve, az esetszám az alábbi megyékben volt a legmagasabb: Baranya (84,63), Somogy (60,17) és Zala (58,89). Az elszámolt eseteket 71,6%-ban a beteg lakóhelye szerinti megye határán belül látták el. A legnagyobb számban szürkehályogműtéteket finanszíroztak. A várólista-csökkentési programban elszámolt esetek között jelentős területi egyenlőtlenségeket találtunk. Az intézményi szerepvállalás is változatos képet mutatott.
Az új típusú koronavírus nanobiofizikája
Authors: Kiss Bálint , Kis Zoltán , Pályi Bernadett , Kellermayer Miklós
Published: April 2022

A Covid-19-pandémia végigsöpört az egész világon, soha nem látott megterhelést okozva egészségügyi rendszereinkben, és kihívások elé állította a biomedicinális kutatást, hogy a járványra mielőbb megfelelő válaszokat adjunk. A modern „egy partikulum” biofizikai módszerek különleges bepillantást engednek a járvány okozója, a SARS-CoV-2 tulajdonságaiba. A vírus tüske­fe­hérjékből álló koronaszerű réteget hordoz a felületén, melyeknek fontos szerepet tulajdonítunk a fertőzés folyamatában. Atomi erőmikroszkóp segítségével sikerült feltárnunk a natív virionok topográfiai szerkezetét és mechanikai tulajdonságait. A tüskefehérjék, rugalmasságuk és mozgékonyságuk révén, dinamikus felületet alkotnak. A virionok meglepően ellenállóak a mechanikai összenyomással szemben, és szerkezetük képes helyreállni a mechanikai behatást követően. A vírus globális szerkezete ellenáll a hőhatásnak, de a hőmérséklet fokozásával a tüskefehérjék disszociálódnak a fe­lü­letről. A SARS-CoV-2 mechanikai és dinamikai sajátosságai hozzájárulnak fertőző képességéhez. Az alkalmazott „egy partikulum” biofizikai módszerek fontos szerepet játszhatnak az egyre gyakoribbá váló vírusfertőzések megértésében és legyőzésében.
TÜRKİYE’DE YAŞAYAN ULUSLARARASI KORUMA VE GEÇİCİ KORUMA STATÜSÜNDEKİ YABANCILARIN ÇALIŞMA İZNİ, İŞ SÖZLEŞMELERİ, DİPLOMA DENKLİK VE MESLEK İCRASINA İLİŞKİN DURUMLARININ HUKUKİ AÇIDAN DEĞERLENDİRİLMESİ
Authors: YILDIZ Ayselin , İZMİRLİOGLU Ayca
Published: April 2022

Türkiye’de yaşayan yabancı uyruklu kişiler farklı statüler altında, farklı mevzuat ve yasal prosedürlere tabi olarak istihdama dahil olmaktadır. Çalışmamızın konusunu teşkil eden uluslararası koruma statüsü ile geçici koruma statüsü sahibi olan yabancılar, 6458 sayılı Yabancılar ve Uluslararası Koruma Kanunu uyarınca ülkemizde çalışma hakkına sahip kılınmıştır. Dolayısıyla uluslararası koruma statüsü sahibi olarak mülteci, şartlı mülteci ve ikincil koruma sahibi yabancılar ile başta Suriye olmak üzere ülkemize kitlesel göç ile gelen yabancılar koşulları sağlamaları durumunda geçici koruma statüsü ile istihdam edilebilmektedir. Diğer taraftan, yabancıların ülkemizde çalışabilmeleri, kanunlarda belirtilen istisnai haller dışında çalışma izni alma şartına bağlanmış olup, yabancıların çalışma izinlerine ilişkin düzenlemeler ise 6735 sayılı Uluslararası İşgücü Kanunu’nda düzenlenmiştir. Bu çalışmada uluslararası koruma ve geçici koruma statüsünde bulunan yabancıların çalışma izinleri, iş sözleşmelerinin bağıtlanması, diploma denklik işlemlerine ilişkin yasal prosedürler ve meslek icrasına yönelik düzenlemeler, başta anayasal düzeyde olmak üzere ilgili kanunlar, yönetmelikler ve sair mevzuat çerçevesinde incelenecektir. Yabancıların ülkemizde farklı statüler ile ikamet etmeleri ve farklı mevzuatlara göre istihdam edilmeleri nedeniyle yeknesak bir yasal süreç söz konusu olamamaktadır. Bu bağlamda, çalışmada, birbirleriyle yakından ilişkili ve kimi zaman birbirine ön koşul olarak sunulan bu konulara ilişkin uluslararası ve ulusal mevzuat bütüncül bir yaklaşımla ele alınarak tahlil edilecek ve ulusal düzenlemelerimiz hakkında birtakım önerilere yer verilecektir.
DURUŞMANIN ALENİYETİ İLKESİ VE SINIRLANDIRILMASI
Authors: ARTANTAŞ Günce
Published: April 2022

Duruşmanın aleniliği ilkesi, muhakeme işlemlerinin kamuya açık olarak yapılmasını ve bunların duyurulabilmesini ifade eder. Söz konusu ilke adil yargılanma hakkının bir parçası olarak hem Anayasa’nın 141.maddesinde hem de Avrupa İnsan Hakları Sözleşmesi’nin 6.maddesinde güvence altına alınmıştır. Kural olarak, duruşma evresinde alenilik esastır. Bununla birlikte, söz konusu hukuki metinlerde aleniyet ilkesinin istisnalarına da yer verilmiştir. Genel ahlak, kamu güvenliği, küçüklerin çıkarları veya özel hayatın gizliliği gerektirdiğinde ya da aleniyetin adil yargılamaya zarar verebileceği kimi özel durumlarda duruşma kapalı yapılabilir. Bu çalışmada kamuya açıklık ilkesinin anlamı, kapsamı ve özellikle kamuya açıklık ilkesine getirilen sınırlamalar, Avrupa İnsan Hakları Mahkemesi’nin içtihatları çerçevesinde incelenmektedir.
6183 SAYILI AMME ALACAKLARININ TAHSİL USULÜ HAKKINDA KANUN’A GÖRE HACZE İŞTİRAK
Authors: KÜÇÜK Alper Tunga
Published: April 2022

Kamu alacağının tahsili, kamu alacağının kamu hizmetlerinin finansmanını sağlamadaki rolü nedeniyle Amme Alacaklarının Tahsil Usulü Hakkında Kanun’da özel olarak düzenlenmiştir. Bu kanunda kamu alacağının tahsili için birçok imtiyazın mevcut olduğu ve kamu alacağının korunduğu görülmektedir. Kamu alacağının korunduğu hükümlerden biri hacze iştiraktir. Hacze iştirak, bir alacaklının kendisinden önce başka bir alacaklının koyduğu hacze kanunda düzenlenen şartlarla iştirak etmesidir. Hacze iştirak için İcra ve İflas Kanunu m. 100’de çeşitli şartlar düzenlenmekle birlikte kamu alacakları için bu şartlar geçerli değildir. Ayrıca kamu alacağı için konulan bir hacze özel hukuk alacaklısının iştiraki mümkün değildir. Kamu alacakları lehine mevcut olan düzenlemelerin isabetli olup olmadığı sorusuna Anayasa’da düzenlenen temel haklar karşısındaki durumu dikkate alınarak cevap verilmelidir. Çalışmada kamu alacaklarına dair hacze iştirak hükümleri, öğretideki görüşler ile Yargıtay kararları ışığında ayrıntılı şekilde incelenmiş ve bu hükümlerin temel haklara aykırılık teşkil edip etmediği hususunda bir sonuca varılmıştır.
Introduction: The Genesis of ‘“Anal” and “Sexual”’
Authors: Brilmyer S. Pearl , Trentin Filippo
Published: April 2022

This introduction contextualizes Lou Andreas-Salomé’s 1916 essay ‘“Anal” and “Sexual”’ within early psychoanalytic debates about anal sexuality, narcissism, and subject-formation, and gestures toward its relevance for recent thinking in queer theory and critical race studies. While Andreas-Salomé’s work has often been read as a gloss to Freud’s sexual theory, we emphasize the originality of her contributions to psychoanalytic discourse. Not only did ‘“Anal” and “Sexual”’ impact Freud’s understanding of the long-lasting influence of anal repression on the psyche, but it anticipates the concerns of more recent theorists with how subjects are gendered and racialized through processes of corporeal symbolization.
René Spitz’s Empty Frames: ‘Hospitalism’, Screen Analysis and the Birth of Infant Psychiatry
Authors: Joice Katie
Published: April 2022

This article casts light on the origins of infant psychiatry by taking a new, interdisciplinary approach to the work of psychoanalyst and film-maker René Spitz. Focusing on his observations of babies living in orphanages, it argues that by undertaking the difficult, and sometimes paradoxical, task of capturing emotional absence and psychological fragmentation on film, Spitz created a new and influential theory of the infant psyche. It considers how this vision of an indeterminate and potentially ‘empty’ infant subject was generated by the institutional care which he sought to undermine. The particular ways in which the institution emerges as a problem and opportunity for child analysts after World War II propelled Spitz into a surprising range of post-war debates on cultural politics. He is revealed as embedded in a complex, interdisciplinary web of discourse, practices and observational strategies, and at the centre of post-war visual research into the environmental origins of mental illness.
Frequency of Metabolic syndrome in Patients with Shoulder Pain
Authors: SARGIN Serdar , ŞAHİN Nilay , KARAHAN Ali Yavuz , AYDIN Zafer
Published: April 2022

Objectives: Shoulder pain is a common cause of disability. There are few studies in the literature linking Metabolic Syndrome (MetS) with shoulder pain and shoulder pathologies. This study aims to determine the frequency of metabolic syndrome in patients with shoulder pain; and whether there was a difference between the two groups in terms of severity and characteristics of shoulder pain.

Methods: In this prospective cross-sectional study, the target population consisted of subjects aged 18 years or older applying to outpatient clinic with shoulder pain. Detailed shoulder examinations were performed. Waist-to-hip ratio and body mass index were calculated. Blood pressures were measured. Fasting blood glucose and lipids level were recorded. A Visual Analogue Scale for current pain was applied.

Results: MetS was diagnosed in 44 of 104 patients. The most common shoulder problems of patients with MetS; were partial tear of rotator cuff muscles, frozen shoulder, and supraspinatus tendinitis in 5 (55.6%), 16 (32.3%), and 10 (51.6%) of the patients, respectively. ROM limitation was found to be statistically significantly higher in patients with MetS in internal and external rotation and passive abduction movements. VAS scores were higher in patients with Mets. While the difference in VAS scores with active movement and at rest was statistically significant, the difference in VAS score in night pain was not statistically significant.

Conclusion: We concluded that there is a clear relationship between shoulder pain and MetS. Awareness of such association may allow early diagnosis of MS and early institution of measures to avoid its results.
COVID-19 ilişkili akut mezenterik iskemi: Derleme
Authors: GÖKÇE Oruç Numan , ALKAN Sevil
Published: April 2022

Koronavirüs hastalığı (COVID-19) akciğer dışı tutulumları ile de mortalite ve morbiditeye neden olmaya devam etmektedir. Enfekte olan kişi sayısı arttıkça, çok farklı klinik sendromlarla ilişkilendirilmiştir. Gastrointestinal tutulumlar ve tromboembolik komplikasyonlar da bildirilmiş akciğer dışı tutulumlar arasındadır. Akut mezenter iskemi de yaşamı tehdit eden, acil bir cerrahi patoloji olup, COVID-19 ilişkili olgular bildirilmiştir. Bu derleme çalışmasında, COVID-19 ilişkili akut mezenter iskemi açısından literatürü gözden geçirmeyi amaçladık.
TRADISI KAHAWOTINO LAMBU (MENEMPATI RUMAH BARU) PADA ETNIS MUNA DI DESA KORIHI, KECAMATAN LOHIA, KABUPATEN MUNA
Authors: Samsul Samsul , Dirman La Ode , Samusu Rahman , Hermina Sitti
Published: April 2022

Penelitian ini bertujuan untuk: (1) menggambarkan eksistensi tradisi kahawotino lambu pada etnis Muna di Desa Korihi Kecamatan Lohia, Kabupaten Muna; 2) menjelaskan pola pewarisan tradisi kahawotino lambu di Desa Korihi Kecamatan Lohia Kabupaten Muna. Metode yang digunakan dalam penelitian ini adalah deskriptif kualitatif. Sumber data dalam penelitian ini terdiri dari data primer dan data sekunder. Teknik pengumpulan data dalam penelitian ini adalah observasi atau pengamatan, yaitu peneliti terjun langsung ke lapangan untuk memperoleh data dan mengumpulkan data. Proses pada kegiatan ini lebih ditekankan pada ketelitian dalam eksistensi dan pola pewarisan tradisi kahawotino lambu. Wawancara dilakukan dengan menggali informasi secara mendalam tentang eksistensi dan pola pewarisan tradisi kahawotino lambu di Desa Korihi, Kecamatan Lohia, Kabupaten Muna dengan informan yang telah ditentukan. Dokementasi dilakukan agar dapat memperkuat data hasil dari wawancara dan observasi. Teknik penentuan informan dalam penelitian ini dilakukan dengan teknik purposive sampling. Data dianalisis dengan teknik reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian ini menunjukkan bahwa tradisi kahawotino lambu merupakan tradisi memasuki rumah baru yang dilakukan oleh suku Muna ketika hendak menempati rumah baru. Tradisi ini oleh suku Muna dianggap sebagai salah satu bentuk rasa syukur kepada Allah Swt., atas rahmat dan rezeki. Tanggapan generasi muda terhadap tradisi kahawotino lambu saat ini, yaitu generasi muda sudah tidak terlalu mempercayai adanya kepercayaan terhadap nenek moyang, mereka beranggapan bahwa tradisi tersebut sudah tidak penting lagi dan mereka lebih mengikuti perkembangan zaman dan kemajuan ilmu pengetahuan dan teknologi. Adapun pola pewarisan tradisi kahawotino lambu di Desa Korihi Kecamatan Lohia Kabupaten Muna terdiri dari tiga cara, yaitu (1) melalui keluarga, (2) dengan berguru, dan (3) pewarisan dalam pertunjukan.
On Robin's criterion for the Riemann Hypothesis
Authors: Vega Frank
Published: April 2022

Robin's criterion states that the Riemann hypothesis is true if and only if the inequality $\sigma(n) 5040$, where $\sigma(n)$ is the sum-of-divisors function of $n$ and $\gamma \approx 0.57721$ is the Euler-Mascheroni constant. In 2022, Vega stated that the possible existence of the smallest counterexample $n > 5040$ of the Robin inequality implies that $q_{m} > e^{31.018189471}$ and $(\log n)^{\beta} < 1.03352795481\times\log(N_{m})$, where $N_{m} = \prod_{i = 1}^{m} q_{i}$ is the primorial number of order $m$, $q_{m}$ is the largest prime divisor of $n$ and $\beta = \prod_{i = 1}^{m} \frac{q_{i}^{a_{i}+1}}{q_{i}^{a_{i}+1}-1}$ when $n$ must be an Hardy-Ramanujan integer of the form $\prod_{i=1}^{m} q_{i}^{a_{i}}$. Based on that result, we obtain a contradiction just assuming the existence of such possible smallest counterexample $n > 5040$ for the Robin inequality. By contraposition, we show that the Riemann hypothesis should be true.
Development of image processing algorithms for an AFM scanner
Authors: Ashby Paul , Baroi Max , Bhatt Ghanshyam , Kao Chiu-Yen , Kivelä Mikko , Kramer Peter , Lakoba Taras , Matz Sean , Ruzayqat Hamza
Published: April 2022

The Lawrence Berkeley National Laboratory working group was presented with three problems involving the improvement of images from an AFM scanner. The first concerned the inpainting of an image for which data is collected via a spiral scan waveform. The second concerned the exploitation of data obtained at different times to obtain better spatial resolution. The third concerned the correction of horizontal positions reported by the sensor, particularly when the scanner is operating at high frequency. Herein is a brief report on the progress and ideas generated by the working group on each of these problems.
Actuating Platform Systems
Authors: Acharya Subas , Atmur Robert , Jayawardana Buddhika , Kramer Peter , Moore Richard , Shinglot Vrushaly , Xiang Rui , Zhong Yimin
Published: April 2022

The purpose of this study is to understand the force and energy balance in the wobble plate drive mechanism referred to as the virtual ellipse drive (VED). The moving affine constraint presented by the precessing wobble plate's contact with the stator and rotor plates offers a subtlety that is difficult to account for in a standard classical mechanics approach. This subtlety has made it difficult to account for energy conservation in simulations, even when including vibration and friction.
Analyzing viscoelastic materials
Authors: Bohun Sean
Published: April 2022

Both deterministic modelling and data analysis are used to characterize a product line of viscoelastic cushions. Classical Kelvin-Voigt and Maxwell models are derived and solved to compare with industry supplied experimental data. A Maxwell model with a nonlinear spring is used to extract an effective viscosity for each product and used to sort the product line. Data analysis techniques are used to find a small set of exemplar cushions, chosen based on their extremal behaviour in the supplied data. These are then used to characterize all the products. Both methods provide a unique way to classify the product offerings in the marketplace.
Global Englishes and the Semiotics of German Radio—Encouraging the Listener's Visual Imagination Through Translingual and Transmodal Practices
Authors: Schaefer Sarah Josefine
Published: April 2022

Due to increasing mediatisation of societies and the global diffusion of English, previous research has paid a great deal of attention to the use of English in contact with other linguistic resources. Traditionally, the focus in studies on global Englishes is predominantly on verbal resources, which are often examined in media corpora. The recent paradigmatic shift towards a conceptualisation of language as a social practice, however, also acknowledges other resources such as music, images and sounds as part of semiotic assemblages in the process of meaning-making. This paper contributes to this current debate and argues for a more holistic view on language illustrated by examples of the use of global Englishes in German radio media texts. The examples show the complexities of translingual and transmodal practices in mass media communication and how English linguistic resources are deeply entangled with other semiotic resources and thereby locally appropriated in semiotic assemblages to stimulate the listener's visual imagination and achieve communicative success in a non-visual medium.
BurnoutEnsemble: Augmented Intelligence to Detect Indications for Burnout in Clinical Psychology
Authors: Merhbene Ghofrane , Nath Sukanya , Puttick Alexandre R. , Kurpicz-Briki Mascha
Published: April 2022

Burnout, a state of emotional, physical, and mental exhaustion caused by excessive and prolonged stress, is a growing concern. It is known to occur when an individual feels overwhelmed, emotionally exhausted, and unable to meet the constant demands imposed upon them. Detecting burnout is not an easy task, in large part because symptoms can overlap with those of other illnesses or syndromes. The use of natural language processing (NLP) methods has the potential to mitigate the limitations of typical burnout detection via inventories. In this article, the performance of NLP methods on anonymized free text data samples collected from the online forum/social media platform Reddit was analyzed. A dataset consisting of 13,568 samples describing first-hand experiences, of which 352 are related to burnout and 979 to depression, was compiled. This work demonstrates the effectiveness of NLP and machine learning methods in detecting indicators for burnout. Finally, it improves upon standard baseline classifiers by building and training an ensemble classifier using two methods (subreddit and random batching). The best ensemble models attain a balanced accuracy of 0.93, test F1 score of 0.43, and test recall of 0.93. Both the subreddit and random batching ensembles outperform the single classifier baselines in the experimental setup.
Study on Sedimentary Environment Elements and Sedimentary Model of Lacustrine Shale in E1f2 Member, Gaoyou Depression, Subei Basin
Authors: Ma Cunfei , Huang Wenjun , Zou Kaizhen , Ma Xiaonan , Liu Zhenyang , Yin He , Liu Shili
Published: April 2022

Although the potential of lake facies shale oil and gas resources is enormous, the lithology is complex, heterogeneous, and obviously controlled by a sedimentary environment. By integrating cores, thin sections, X-ray diffraction analysis, trace elements, organic geochemical indexes, and paleontological data, this work studies sedimentary environment elements and sedimentary model of shale in the E1f2 member, Gaoyou Depression, Subei Basin. The shale in the E1f2 member is completely shore lacustrine deposits forming into the hot dry climate of tropical central and south Asia. The lake basin extended continuously, with brackish water, strong reduction, and medium water stratification. The transgression resulted in the rapid rise of water, salinity, reducibility, and water stratification. As the climate becomes wetter, the E1f2 water level, salinity, reduction, and stratification decrease. The shale in E1f2 members is characterized by sedimentary zones, which are divided into muddy water desalination deposit in the flooded zone, clear water salinization deposit in the transition zone, and still water salinization deposited in the clear water zone. Under palaeotopography settings of E1f2 members, combining characteristics of vertical stratification and the plane zone of the lake, an integrated sedimentary model of lacustrine shale in a flat platform has been established under climate and transgression control. The plane area of the lake could be divided into the slow slope zone, sub-depression zone, processes zone, deep slope zone, and deep depression zone, corresponding roughly to the sedimentary zones of the flooded zone, transition zone, and clear water zone. Moreover, the oil shale enriched in low-lying parts of the paleotopography is mainly deposited at the end of muddy water areas and clear water areas.
The Association Between Cyclooxygenase-2 –1195G/A (rs689466) Gene Polymorphism and the Clinicopathology of Lung Cancer in the Japanese Population: A Case-Controlled Study
Authors: Sun Rong , Tanino Ryosuke , Tong Xuexia , Isomura Minoru , Chen Li-Jun , Hotta Takamasa , Okimoto Tamio , Hamaguchi Megumi , Hamaguchi Shunichi , Taooka Yasuyuki , Isobe Takeshi , Tsubata Yukari
Published: April 2022

The single nucleotide polymorphisms of COX-2 gene, also known asPTGS2, which encodes a pro-inflammatory factor cyclooxygenase-2, alter the risk of developing multiple tumors, but these findings are not consistent for lung cancer. We previously reported that the homozygous COX-2 –1195A genotype is associated with an increased risk for chronic obstructive pulmonary disease (COPD) in Japanese individuals. COPD is a significant risk factor for lung cancer due to genetic susceptibility to cigarette smoke. In this study, we investigated the association between COX-2 –1195G/A polymorphism and lung cancer susceptibility in the Japanese population. We evaluated the genotype distribution of COX-2 –1195G/A using a polymerase chain reaction-restriction fragment length polymorphism assay for 330 newly diagnosed patients with lung cancer and 162 healthy controls. Our results show that no relationship exists between the COX-2 –1195G/A polymorphism and the risk of developing lung cancer. However, compared to the control group, the homozygous COX-2 –1195A genotype increased the risk for lung squamous cell carcinoma (odds ratio = 2.902; 95% confidence interval, 1.171–7.195;p= 0.021), whereas no association is observed with the risk for adenocarcinoma. In addition, Kaplan-Meier analysis shows that the genotype distribution of homozygous COX-2 –1195A does not correlate with the overall survival of patients with lung squamous cell carcinoma. Thus, we conclude that the homozygous COX-2 –1195A genotype confers an increased risk for lung squamous cell carcinoma in Japanese individuals and could be used as a predictive factor for early detection of lung squamous cell carcinoma.
Recent Advances in Investigating Functional Dynamics of Chromatin
Authors: Shi Xiangyan , Zhai Ziwei , Chen Yinglu , Li Jindi , Nordenskiöld Lars
Published: April 2022

Dynamics spanning the picosecond-minute time domain and the atomic-subcellular spatial window have been observed for chromatin in vitro and in vivo. The condensed organization of chromatin in eukaryotic cells prevents regulatory factors from accessing genomic DNA, which requires dynamic stabilization and destabilization of structure to initiate downstream DNA activities. Those processes are achieved through altering conformational and dynamic properties of nucleosomes and nucleosome–protein complexes, of which delineating the atomistic pictures is essential to understand the mechanisms of chromatin regulation. In this review, we summarize recent progress in determining chromatin dynamics and their modulations by a number of factors including post-translational modifications (PTMs), incorporation of histone variants, and binding of effector proteins. We focus on experimental observations obtained using high-resolution techniques, primarily including nuclear magnetic resonance (NMR) spectroscopy, Förster (or fluorescence) resonance energy transfer (FRET) microscopy, and molecular dynamics (MD) simulations, and discuss the elucidated dynamics in the context of functional response and relevance.
Personalized Disease Monitoring in Pediatric Onset Multiple Sclerosis Using the Saliva Free Light Chain Test
Authors: Ganelin-Cohen Esther , Tartakovsky Evgeny , Klepfish Ely , Golderman Sizilia , Rozenberg Ayal , Kaplan Batia
Published: April 2022

Background

Development of new safe methods of monitoring disease activity in the pediatric onset multiple sclerosis (POMS) is a challenging task, especially when trying to refrain from frequent MRI usage. In our recent study, the saliva immunoglobulin free light chains (FLC) were suggested as biomarkers to discriminate between remission and active MS in adults.

Objectives

To assess utility of saliva FLC measurements for monitoring disease activity in POMS.

Methods

We used semiquantitative Western blot analysis to detect immunoreactive FLC monomers and dimers and to calculate the intensity of their bands. Statistical tests included Firth logistic regression analysis suitable for small sample sizes, and Spearman’s non-parametric correlation.

Results

In naive POMS patients, the saliva levels of FLC in relapse were significantly higher than those in remission. Significant correlation was found between FLC levels (monomers, dimers or both) and the load of enhanced lesions in MRI scans. FLC levels may be reduced under treatment, especially as result of corticosteroids therapy. Follow-up of individual patients showed the correspondence of changes in the FLC levels to MRI findings.

Conclusions

Our results show the potential of the non-invasive saliva FLC test, as a new tool for monitoring the disease activity in POMS.
Human Breast Milk: From Food to Active Immune Response With Disease Protection in Infants and Mothers
Authors: Lokossou Gatien A. G. , Kouakanou Léonce , Schumacher Anne , Zenclussen Ana C.
Published: April 2022

Breastfeeding is associated with long-term wellbeing including low risks of infectious diseases and non-communicable diseases such as asthma, cancer, autoimmune diseases and obesity during childhood. In recent years, important advances have been made in understanding the human breast milk (HBM) composition. Breast milk components such as, non-immune and immune cells and bioactive molecules, namely, cytokines/chemokines, lipids, hormones, and enzymes reportedly play many roles in breastfed newborns and in mothers, by diseases protection and shaping the immune system of the newborn. Bioactive components in HBM are also involved in tolerance and appropriate inflammatory response of breastfed infants if necessary. This review summarizes the current literature on the relationship between mother and her infant through breast milk with regard to disease protection. We will shed some light on the mechanisms underlying the roles of breast milk components in the maintenance of health of both child and mother.
The Associations of rs1799724 and rs361525 With the Risk of Ankylosing Spondylitis Are Dependent on HLA-B27 Status in a Chinese Han Population
Authors: Sheng Nan , Gao Yingying , Li Hui , Wang Wenwen , Geng Linyu , Zhang Bo , Huang Qiang , Wang Xueqin , Sun Lingyun
Published: April 2022

Objectives

Human leucocyte antigen B27 (HLA-B27) is an important biomarker for ankylosing spondylitis (AS). However, delay in the diagnosis of AS is still common in clinical practice. Several single nucleotide polymorphisms (SNPs) in the coding gene of tumor necrosis factor alpha (TNFα) have been reported to be AS susceptibility loci. Our aim was to explore whether SNPs in TNFα could be used to improve the performance of HLA-B27 for predicting AS.

Methods

Five SNPs (rs1799964, rs1800630, rs1799724, rs1800629, and rs361525) spanning TNFα were genotyped by qPCR-Invader assay in 93 AS patients and 107 healthy controls for association analysis and linkage disequilibrium (LD) analysis. Random forest algorithm was utilized to construct the predictive classifiers for AS. HLA-B was genotyped by PCR-sequence-based typing in a subset of the HLA-B27-positive subjects (38 AS patients and 5 healthy controls).

Results

The T allele of rs1799724 was verified to significantly increase the risk of AS (OR = 4.583, p < 0.0001), while the A allele of rs361525 showed an association with the reduced AS risk (OR = 0.168, p = 0.009). In addition, the rs1799964T-rs1800630C-rs1799724T-rs1800629G-rs361525G haplotype was significantly associated with a higher risk of AS (p < 0.0001). The optimal set of variables for classifiers to predict AS only consisted of HLA-B27. Strong associations with HLA-B27 status were found in both rs1799724 (p < 0.0001) and rs361525 (p = 0.001), and all the analyzed HLA-B27-positive subjects carried HLA-B*27:04 or HLA-B*27:05.

Conclusion

In the Chinese Han population, the minor allele T of rs1799724 could increase the risk of AS, while the minor allele A of rs361525 protects individuals from AS. However, the contributions of rs1799724 and rs361525 to AS risk were dependent on HLA-B27 status, suggesting the importance of taking the independence and specificity into consideration in AS susceptibility loci studies.
Tim-3 Expression Causes NK Cell Dysfunction in Type 2 Diabetes Patients
Authors: Wang Hui , Cao Kangli , Liu Siyu , Xu Yuanhong , Tang Ling
Published: April 2022

Type 2 diabetes mellitus (T2DM) is characterized by high blood glucose levels and chronic low-grade inflammation. It shows a strong association with obesity and immune dysfunction, which makes T2DM patients more susceptible to infectious diseases. NK cells play an important role in pathogen control and tumor surveillance. However, whether NK cell distribution and functional status are altered in T2DM is unclear. To address this issue, we compared surface receptor expression and cytokine production between peripheral blood NK cells from 90 T2DM patients and 62 age- and sex-matched healthy controls. We found a significantly lower frequency and absolute number of NK cells in patients than in controls. Interestingly, the expression of inhibitory receptor Tim-3 was significantly increased, while the expression of the activating receptor NKG2D was significantly decreased, in T2DM NK cells. Both TNF-α secretion and degranulation capacity (evidenced by CD107a expression) were dampened in NK cells from patients. The expression of Tim-3 on NK cells correlated positively with both HbA1c and fasting blood glucose levels and negatively with the percentage and absolute number of total NK cells and was associated with increased NK cell apoptosis. In addition, Tim-3 expression on NK cells negatively correlated with TNF-α production, which could be restored by blocking Galectin-9/Tim-3 pathway. Our results suggest that NK cell dysfunction secondary to augmented Tim-3 expression occurs in T2DM patients, which may partly explain their increased susceptibility to cancer and infectious disease.
Frequent Infection of Cats With SARS-CoV-2 Irrespective of Pre-Existing Enzootic Coronavirus Immunity, Brazil 2020
Authors: Oliveira-Filho Edmilson F. de , de Carvalho Otávio V. , Carneiro Ianei O. , Fernandes Fagner D’ambroso , Vaz Sara Nunes , Pedroso Célia , Gonzalez-Auza Lilian , Urbieta Victor Carvalho , Kühne Arne , Mayoral Rafaela , Jo Wendy K. , Moreira-Soto Andrés , Reusken Chantal B. E. M. , Drosten Christian , Brites Carlos , Osterrieder Klaus , Netto Eduardo Martins , Ristow Luiz Eduardo , Maia Rita de Cassia , Vogel Fernanda S. Flores , Almeida Nadia Rossi de , Franke Carlos Roberto , Drexler Jan Felix
Published: April 2022

Carnivores such as cats and minks are highly susceptible to SARS-CoV-2. Brazil is a global COVID-19 hot spot and several cases of human-to-cat transmission have been documented. We investigated the spread of SARS-CoV-2 by testing 547 domestic cats sampled between July-November 2020 from seven states in southern, southeastern, and northeastern Brazil. Moreover, we investigated whether immune responses elicited by enzootic coronaviruses affect SARS-CoV-2 infection in cats. We found infection with significantly higher neutralizing antibody titers against the Gamma variant of concern, endemic in Brazil during 2020, than against an early SARS-CoV-2 B.1 isolate (p<0.0001), validating the use of Gamma for further testing. The overall SARS-CoV-2 seroprevalence in Brazilian cats during late 2020 validated by plaque reduction neutralization test (PRNT90) was 7.3% (95% CI, 5.3-9.8). There was no significant difference in SARS-CoV-2 seroprevalence in cats between Brazilian states, suggesting homogeneous infection levels ranging from 4.6% (95% CI, 2.2-8.4) to 11.4% (95% CI, 6.7-17.4; p=0.4438). Seroprevalence of the prototypic cat coronavirus Feline coronavirus (FCoV) in a PRNT90 was high at 33.3% (95% CI, 24.9-42.5) and seroprevalence of Bovine coronavirus (BCoV) was low at 1.7% (95% CI, 0.2-5.9) in a PRNT90. Neutralizing antibody titers were significantly lower for FCoV than for SARS-CoV-2 (p=0.0001), consistent with relatively more recent infection of cats with SARS-CoV-2. Neither the magnitude of SARS-CoV-2 antibody titers (p=0.6390), nor SARS-CoV-2 infection status were affected by FCoV serostatus (p=0.8863). Our data suggest that pre-existing immunity against enzootic coronaviruses neither prevents, nor enhances SARS-CoV-2 infection in cats. High SARS-CoV-2 seroprevalence already during the first year of the pandemic substantiates frequent infection of domestic cats and raises concerns on potential SARS-CoV-2 mutations escaping human immunity upon spillback.