bluuebunny/crossref_metadata_2025 huggingface dataset:
Modelo educacional usando impressora 3D na prototipagem do ensino para resolução de problemas na saúde
Authors: Mendes Luis Miguel Carvalho , Rocha Sofia Caroline Cavalcante , Miranda Sonara Santos , Santos Iago Figueiredo dos , Lino Lucas Arruda , Oliveira Ivo Sócrates Moraes de , Rocha Pedro Emanuel Cavalcante , Lopes Francicero Rocha , Azevedo David Salen Alves , Pereira Paulo Henrique Silva , D’Alessandro Walmirton Bezerra
Published: January 2025

Reações bioquímicas, fisiológicas e imunológicas decorrentes da homeostasia humana podem ser melhor explicadas com um modelo preciso da realidade impresso. Criação de estruturas biológicas através da impressão 3D auxiliam os alunos da área da saúde no melhor entendimento de assuntos complexos. Sair do viés slide e vídeos animados, para estruturas físicas táteis e de montagem, para que o aluno se torne protagonista, auxilia no estímulo do conhecimento e saberes educacionais dos discentes. Este estudo busca apresentar uma proposta de aplicação para a impressora 3D no contexto educacional, em uma universidade do município de Gurupi-TO (UNIRG), associando-a à resolução de problemas. Na ocasião, os estudantes usaram conhecimentos adquiridos em sala para atuar sobre o problema que permeia várias instituições de ensino: a falta de material didático para uso em atividades práticas. A partir disso, usar a metodologia ativa Design Thinking para auxiliar no processo, construindo ideias e protótipos para uso como material didático. Os resultados apontam que a impressora 3D pode facilitar o ensino de conteúdos que compõem o currículo acadêmico, seja estimulando os estudantes na construção de modelos ou fazendo uso de modelos prontos como material didático.
Função auditiva e triagem do processamento auditivo central em crianças e adolescentes com asma e rinite: Estudo preliminar
Authors: Santos Ranielly Santana dos , Lima Thales Rafael Correia de Melo , Sena junior Luiz Carlos Oliveira , Figueiredo Emeline Ramos Prata , Nascimento Camila Emily de Jesus do , Nascimento Regina Santos , Taguchi Carlos Kazuo
Published: January 2025

A asma e a rinite se destacam entre as alergias mais frequentes na população brasileira. Estudos mostraram que indivíduos com asma e rinite alérgica podem apresentar um risco duas vezes maior de desenvolvimento da otite média, o que ressalta a importância de investigar a função auditiva em crianças com essas condições, pois a problemas no desenvolvimento auditivo pode afetar gravemente o desenvolvimento da fala, linguagem e aprendizagem. No presente estudo, o objetivo foi analisar os resultados da avaliação da função auditiva e triagem do processamento auditivo central de crianças e adolescentes com asma e rinite. A amostra foi composta por 17 pacientes com idade entre três (3) e 17 anos, de ambos os gêneros, com diagnóstico clínico de asma e rinite. Todos foram submetidos à avaliação audiológica básica, que incluiu audiometria tonal e logoaudiometria e análise das medidas de imitância acústica, ao potencial evocado auditivo de tronco encefálico para a análise de integridade de via auditiva central e triagem do processamento auditivo central por meio de uma bateria simplificada. O estudo revelou audição periférica e integridade das vias auditivas centrais dentro dos padrões de normalidade, porém ocorreu uma alta frequência de falha na avaliação simplificada do processamento auditivo central. Esses achados ressaltam a importância de avaliações completas e encaminhamento para intervenções precoces com vistas à redução do impacto dessas alterações, principalmente de linguagem, no desenvolvimento das crianças.
Hepatite autoimune em paciente portador do vírus da imunodeficiência humana: Relato de caso
Authors: Guedes Rachel Leite , Teodoro João Antônio Ayres da Motta , Mendes Liliana Sampaio Costa , Jucá Norma Thomé , Carneiro Marcos de Vasconcelos
Published: January 2025

A hepatite autoimune (HAI) é uma doença hepática crônica que predominantemente afeta mulheres, caracterizada por hipergamaglobulinemia, positividade para autoanticorpos, e alterações histológicas no fígado. Sem tratamento, pode evoluir para cirrose e insuficiência hepática. A síndrome inflamatória de reconstituição imune (SIRI), que ocorre após o início da terapia antirretroviral em pacientes com HIV (vírus da imunodeficiência humana), pode desencadear HAI em indivíduos com predisposição genética para doenças autoimunes. A SIRI leva a uma intensificação dos sintomas inflamatórios devido à reação excessiva do sistema imunológico a infecções oportunistas preexistentes. O presente artigo objetiva apresentar um relato de caso de uma paciente vivendo com HIV que desenvolveu HAI após o início da terapia antirretroviral. O manejo clínico com imunossupressores mostrou-se eficaz, destacando a importância do acompanhamento contínuo para a identificação precoce de complicações associadas e o ajuste terapêutico adequado.
Perfil socioeconômico e odontológico de pacientes pré-transplante renal acompanhados em um centro médico de referência no Estado do Ceará
Authors: Saraiva Vanessa Moura , Silva Paulo Goberlânio de Barros , Monte Jessica de Souza , Santos Eliardo Silveira , Melo Aline Rocha de
Published: January 2025

O presente estudo visa levantar o perfil socioeconômico e odontológico de pacientes pré-transplante renal. Realizou-se um levantamento do perfil socioeconômico e odontológico de Doentes Renais Crônicos (DRC) do Hospital Geral de Fortaleza (HGF) em agosto/2023, afim de caracterizar e coletar dados para auxílio em planejamento e otimização dos atendimentos. Incluiu-se maiores de 18 anos, excluiu-se aqueles com tratamento dentário prévio no HGF, portadores do Vírus da Imunodeficiência Humana (HIV) instáveis, hepatite B e C, gestantes, e que não assinaram Termo de Consentimento Livre e Esclarecido. Anamnese, exame clínico e hematológicos foram realizados em 30 pacientes, complementando-se com Escala BOAS-m (Escala de Avaliação Oral Beck Modificada) e índice CPOD (Dentes Cariados Perdidos e Obturados), usando-se nível de significância de 95%. Constatou-se 60% com evolução de 1 a 4 anos da doença, hemácias (43,3%) e hemoglobinas (46,7%) diminuídas, uréia (96,7%) e creatinina (100%) elevadas. Reabilitação dentária necessária em 83,3%, 53,4% tendo referido queixa de dor, estética, mastigação, sangramento e xerostomia, assim como 66,7% não ido ao dentista há mais de 1 ano e 26,7% sentido resistência no atendimento odontológico externo ao Hospital. O CPOD caracterizou-se muito alto (17.53 ± 8.09) e, a escala BOAS- m (8.60 ± 2.28), leve. Correlacionando-se as variáveis com a escala BOAS-m, não foram achados resultados estatisticamente relevantes que associassem as condições bucais com a anamnese realizada (p > 0,05). Os pacientes DRC apresentaram múltiplas necessidades ao chegarem no serviço de Odontologia, reiterando a importância da presença do cirurgião-dentista durante o pré e pós-operatório.
Radiotrophic fungi and their use as bioremediation agents of areas affected by radiation and as protective agents
Authors: Tibolla Matheus Henrique , Fischer Janaína
Published: January 2025

Nuclear waste, from nuclear fuel and nuclear accidents, represents a great risk to the environment and human beings, causing several problems such as malformation, and cancer, it can turn areas uninhabitable, causing changes in the fauna and flora of entire areas. In the search for a more effective way to deal with such contaminants, it is proposed the use of radiotrophic fungi, such as those found inhabiting the reactor of Chernobyl in Ukraine, the poles, and the international space station, due to their high resistance to these contaminants, the power of absorption of ionizing radiation and the deposition of radioisotopes in their cell walls, making possible the removal of them from the environment in which they are found, as well as the consumption of organic matter, such as the graphite present in the reactor number 4 of Chernobyl. Another property to be explored is the protective use of these organisms to reduce the incidence of ionizing radiation in areas of interest and protect human beings. Therefore, this research aimed to study the mechanisms of action and the effectiveness of these bioremediation agents. The research consisted of a bibliographical review, using database resources and the library collection of the University of Passo Fundo, totaling 56 materials (articles and books), after compilation and evaluation, it can be concluded that radiotrophic fungi are promising as bioremediation agents, with potential for protecting equipment, human beings and as biosensors to detect the presence of ionizing radiation.
Herbal hepatotoxicity: Difficulties in the diagnosis and treatment of liver lesions by borage oil
Authors: Baldon Rodrigo Yndly , Barbosa Ana Clara Name Ribeiro , Mesquita Natália Faria , Sanson Nicole Zanzarini , Chiovato Ana Flávia Carrijo , Gomide Geisa Perez Medina
Published: January 2025

Introduction: The use of herbal medicines has increased over the past 20 years as a complementary therapy for various diseases. However, the commercialization of these products is not preceded by a guarantee of safety. This article aims to report the use of borage oil or Borago officinalis (BO), beneficial for menopause-related symptoms, however, it may contain pyrrolizidine alkaloids (AP), a hepatotoxic toxin. Methodology: a study of the patient's electronic medical record was conducted. Case report: 53-year-old woman admitted to emergency room with jaundice, asthenia, hyporexia and pain in the right hypochondrium (HD) for 10 days after use of the herbal medicine Niolix® (BO), being initially diagnosed with acute hepatitis induced by BO. Liver biopsy revealed intense lymphocyte inflammatory infiltrate, in addition to plasma cells, neutrophils and macrophages, with aggression to the limiting plaque and hepatocytes. After the end of the corticosteroid treatment, there was a new increase in aminotransferases and the appearance of autoantibodies, leading to the hypothesis of autoimmune hepatitis triggered by BO. Immunosuppressive treatment was instituted, with significant improvement in the condition. Conclusion: this report exemplifies the diversity of liver lesions induced by herbs, as well as drugs, supplements, and medications, calling attention to the strict follow-up of cases, with possible changes in diagnosis and conduct during treatment.
Consumo de alimentos ultraprocessados entre crianças de até dois anos nas regiões Norte e Nordeste do Brasil: Revisão integrativa
Authors: Oliveira Luana Alves de , Ferreira Sheila dos Santos , Sá Natália Pinheiro de , Ferreira Ana Clara Lopes , Alcântara Juliane Siomara da Silva , Soares Jéssica Adriana Dias , Soares Juliana Mikaelly Dias
Published: January 2025

O alto consumo de alimentos ultraprocessados (AUP) em lactentes pode acarretar consequências a curto, médio e a longo prazo. Pode ocorrer déficit no crescimento, obesidade e o acometimento de doenças crônicas não transmissíveis. Diante disso, o objetivo deste trabalho foi revisar a literatura sobre o consumo de alimentos ultraprocessados entre lactentes, com enfoque nas regiões norte e nordeste do país, a fim de compreender de forma abrangente a idade média e fatores determinantes para a introdução desses alimentos. Foram identificados 431 artigos, dos quais foram excluídos na triagem e por critérios de exclusão 422 artigos. Com isso, 9 trabalhos originais foram incluídos na presente revisão. Do total de artigos, 5 artigos realizaram estudos transversais e 4 artigos são estudos de coorte. Com relação à idade média de introdução dos AUP, apenas dois estudos informaram e ambos com a mesma média de 6 meses. Há nas regiões Nordeste e Norte do país um consumo prevalente de AUP. O qual, em vários estados do Nordeste, está associado principalmente a baixa renda, baixa escolaridade e amamentação insuficiente (exclusiva ou complementar). Ademais a isso, na região Norte há um consumo crítico de AUP pela população indígena relacionado ao contato com pessoas fora do ambiente familiar e hábitos alimentares diferentes do culturalmente observado. No entanto, esse comportamento alimentar prevalente de alto consumo de AUP é passível de mudanças, desde que ocorra planejamento de ações, viabilidade de políticas públicas e sociais estruturantes.
Mixotrophic growth of Tetraselmis viridis in axenic culture
Authors: Zhondareva Yana D. , Trenkenshu Rudolf P.
Published: January 2025

On the example of laboratory culture of Tetraselmis viridis (Rouchijajnen) R.E.Norris, Hori & Chihara, 1980, the possibility of mixotrophic growth of microalgae in the cumulative axenic cultivation mode was experimentally demonstrated. The implementation of mixotrophy consisted in supplying an additional source of energy and carbon to the initial nutrient medium of glycerol (5.575 g/l). Axenic conditions were provided by a single addition of 2.5 g/l of a chemical antibacterial agent, amoxicillin (C16H19N3O5S) to the nutrient medium at the beginning of the experiment. For an approximate assessment of the degree of bacterial contamination of cultures in the control and experiment, data from measurements of the optical density of the supernatant (in the red region of the spectrum, D750), obtained after centrifugation of the control and experimental samples, were used. These data showed that during the second day of cultivation in the control, there was a rapid growth of concomitant microorganisms, and inhibition of microalgae growth began. In the experiment with amoxicillin, bacterial growth was almost not observed. By the difference in optical densities in the red region of the spectrum (D750) of the culture and the supernatant, the density of the culture T. viridis was determined. using the previously found coefficient. In the control, the culture reached a maximum density of 1.5 g/l on the 5th day of cultivation, and in the experiment, the maximum density during the same time increased to 4 g/l. Analysis of density curves made it possible to identify areas of linear growth and determine the maximum culture productivity both in the control (0.38 gl-1∙day-1) and the experiment with amoxicillin (1.11 gl-1∙day-1). Compared to similar but photolithotrophic growing conditions, T. viridis (growth rate in the linear area of 0.42 gl-1∙day-1), a slight rate decrease was observed in the control. In the experiment, the growth rate of axenic mixotrophic culture was 2.5 times higher than that of photolithotrophic culture.
mpowering Education: Transformational Leadership Creates Inspiring Work Climates to Boost Teacher Performance
Authors: Nurrizayani Nurrizayani , Niswanto Niswanto , Usman Nasir
Published: January 2025

The principal's leadership plays a crucial role in shaping the work dynamics of teachers, necessitating a strong commitment to offering clear direction and active support to the teaching staff. Furthermore, a favorable work environment encourages effective communication between the principal and the teachers. This research examines the effect of transformational leadership and work climate on school teacher performance. Employing a quantitative approach with an ex post facto design, the study involved 70 respondents selected randomly from six schools with A and B accreditation. Data were gathered using validated questionnaires, and the hypothesis was tested through multiple linear regression analysis. The findings revealed that transformational leadership significantly influenced teacher performance, with a t-value of 3.698 and a significance level of 0.005. Additionally, the work climate had a notable effect, reflected by a t-value of 2,842 and a significance level of 0.005. When combined, transformational leadership and work climate considerably impacted teacher performance, as evidenced by an F-value of 29.357 and a significance level of 0.000. This research underscores the critical role of principals as motivating leaders and emphasizes the importance of fostering a supportive work environment to boost teacher performance in schools.
Spirituality-Driven Public Relations with The Panca Reputation Pesantren in Image Building
Authors: Najiburahman Najiburahman , Khusnuridlo Moh , Muhith Abd , Imam Ombra A
Published: January 2025

This study aims to analyze the contribution of spirituality-based public relations management in building the image of Islamic boarding schools in society, based on Fombrun's perspective. This study is based on the importance of Islamic boarding schools as educational institutions that educate students and contribute to the social and cultural welfare of the surrounding community. The research approach used is qualitative with a case study type, where data is collected through observation, in-depth interviews, and documentation. Data analysis used the Miles and Huberman interactive model, including data condensation, presentation, and conclusion. The study results indicate that the development of Fombrun's theory from the perspective of non-profit Islamic boarding school organizations produces the concept of “Panca Reputasi Pesantren”, which includes credibility, reliability, trustworthiness, responsibility, and local engagement elements. “Panca Reputasi Pesantren” integrates spiritual values with modern management strategies. This concept helps pesantren strengthen relationships with stakeholders and face competition with other educational institutions. This research has implications for expanding the concept of reputation in the context of non-profit organizations, primarily community-based religious institutions. It opens up space for further studies on spirituality-based reputation management.
Pengaruh Edukasi Kesehatan tentang SADARI terhadap Pengetahuan dan Keterampilan Siswi di Sekolah Mambaul Hikam Desa Tegal Mojo Kabupaten Probolinggo
Authors: Aisyah Siti , Andayani Sri Astutik , J.A.H Maulidiyah
Published: January 2025

Breast cancer remains one of the leading causes of death among women, often due to late detection. Early detection can be achieved through Breast Self-Examination (BSE), which helps identify abnormalities early. This study examines the impact of health education about BSE on the knowledge and skills of female students at Mambaul Hikam School, Tegal Mojo, Probolinggo. A quasi-experimental design was used with pretest-posttest groups. The population comprised 115 students, and 90 respondents were selected through probability sampling using the simple random sampling method. Data were collected using questionnaires and observation checklists and analyzed with Wilcoxon and Mann-Whitney tests. The findings show a significant increase in knowledge and skills in the intervention group after health education (p = 0.000), highlighting the effectiveness of BSE education in improving early detection capabilities among students. This study emphasizes the importance of structured health education to enhance knowledge and skills for early breast cancer detection.
Tradisi Bapukung pada Masyarakat Suku Banjar dan Pengaruhnya terhadap Pertumbuhan Anak di Desa Ujung Purui Kabupaten Tabalong
Authors: Najwa Nur , Hidayah Nor , Andini Najwa Femilia , Prastricia Meily Andini , Hasanah Nur , Putri Andini Octaviana
Published: January 2025

Traditions are culturally ingrained practices passed down through generations, reflecting noble values. The Banjar tribe in South Kalimantan upholds the Baayun Bapukung tradition, a childcare practice involving placing infants in a sitting position wrapped in cloth and gently swinging them. This study examines the Bapukung tradition's significance in Ujung Purui Village and its impact on child growth. Using a qualitative phenomenological approach, data were collected through interviews, observations, and documentation, analyzed with NVivo software, and interpreted via Max Weber's social action theory. The results indicate that the community perceives Baayun Bapukung as a beneficial tradition supporting infant health and development. Rational and value-based motives underlie the practice, aligning with Weber’s instrumental rationality. However, pediatricians highlight potential risks, advising against tight swaddling or excessive swinging due to possible respiratory and physical complications. The study emphasizes bridging traditional practices with modern medical insights to support cultural preservation and child welfare
Analisis Konsumsi Hijau pada Kegiatan Car Free Day dalam Menciptakan Ekonomi Hijau di Alun-Alun Kota Kraksaan
Authors: Pradani Rizki Febri Eka , Putri Sephia Eka Amalia , Safitri Indah Nurlaili , Wulandari Evi Sri
Published: January 2025

Car Free Day is an initiative by the Indonesian government to reduce air pollution and promote environmentally friendly practices. In Kraksaan City, this program not only supports local SMEs by providing selling opportunities but also attracts significant public participation. This study aimed to assess the awareness level of Car Free Day visitors regarding green consumption and to identify barriers to adopting environmentally friendly consumer behavior. Using qualitative methods and descriptive research design, data were gathered through observation, interviews, and documentation. Results indicate that both visitors and participating SMEs lack understanding of green consumption principles. Many continue to consume and utilize non-environmentally friendly products, particularly in food packaging and transport choices. This study highlights the need for targeted education and policy measures to encourage sustainable consumption patterns during public events like Car Free Day.
Hubungan Konsumsi Makanan Cepat Saji dan Aktivitas Fisik dengan Status Gizi pada Usia Remaja di SMA Negeri 1 Pajangan
Authors: Mucharomah Ammelia , Fitriani Rosmauli Jerimia
Published: January 2025

Adolescence is a critical period for growth and development, influenced significantly by lifestyle choices. This study investigates the relationship between fast food consumption, physical activity, and nutritional status among adolescents at SMA Negeri 1 Pajangan. Using a cross-sectional design, the research involved 243 respondents selected through random sampling. Data collection methods included Food Frequency Questionnaires (FFQ), 24-hour Physical Activity Level (PAL) recall forms, and anthropometric measurements. The Spearman correlation test revealed no significant relationship between fast food consumption and nutritional status (p=0.468) or between physical activity and nutritional status (p=0.648). These findings highlight the complex factors influencing nutritional status beyond diet and exercise, suggesting the need for multifaceted approaches to address adolescent health. The study underscores the importance of balanced interventions incorporating dietary education and physical activity to improve adolescent nutritional outcomes.
Tingkat Penanganan Penyakit Jantung di RSUD Arifin Achmad dan Implikasinya bagi Masyarakat
Authors: Safira Siska Dwi
Published: January 2025

Heart disease remains a leading cause of mortality globally and in Indonesia, emphasizing the importance of effective healthcare services. This study analyzes the level of heart disease management at Arifin Achmad Regional Hospital and its implications for public health in Riau Province. Using a literature review method, secondary data from scientific journals, Ministry of Health reports, and related publications were analyzed. The findings reveal that Arifin Achmad Hospital offers comprehensive heart care services, including intensive care, interventional cardiology, and inpatient and outpatient services. Despite these capabilities, challenges such as limited access for rural communities, a shortage of specialists, and insufficient facilities persist. Addressing these issues requires improving service capacity, adding medical professionals, and developing preventive education programs. Collaboration among hospitals, local governments, and organizations is critical to ensure equitable access and high-quality heart health services in the region
Pengaruh Literasi Informasi terhadap Model Pembelajaran Problem Based Learning
Authors: Sunyianto Sunyianto , Pasaribu Ida M. , Zakiah Diana M. , Azmi M. Fadlul , Kerisman Kerisman , Markus Markus
Published: January 2025

Information literacy is a critical skill that supports learning processes, especially in Problem-Based Learning (PBL) models, which emphasize critical thinking and problem-solving. This study aims to investigate the influence of information literacy on PBL models in vocational education at SMK Negeri 10 Medan. Using a quantitative descriptive method, the research involved 55 students, divided into experimental and control groups. The experimental group applied PBL, while the control group used conventional learning models. Results revealed a significant improvement in the information literacy skills of the experimental group, with pretest and posttest average scores increasing from 52.00 to 82.92, compared to the control group (pretest 51.50, posttest 79.63). Statistical analysis confirmed the significant impact of PBL on improving information literacy. The findings suggest that PBL enhances students' engagement, critical thinking, and ability to utilize information effectively. This research advocates for integrating PBL in educational curricula to foster higher-order thinking skills and better academic outcomes
Pusat Pelatihan Dan Pemberdayaan Nelayan Berkelanjutan Di Desa Kurau Bangka Tengah
Authors: Wulandari Mayang Resfelia , Arsa Rhaka Ananda
Published: January 2025

Penelitian ini bertujuan untuk mengetahui apakah pembangunan Gedung Pusat Pelatihan Dan Pemberdayaan Nelayan Berkelanjutan di Desa Kurau layak secara ekonomi berdasarkan parameter kelayakan menggunakan metode Net Present Value (NPV), Benefit Cost Ratio (BCR), Internal Rate Of Return (IRR) dan Pay Back Period (PP). Metode pengumpulan data dalam penelitian ini adalah dengan menggunakan data kuantitatif melalui survei dan analisis statistik untuk mengukur dampak pelatihan terhadap pendapatan dan keterampilan nelayan. Selain itu, kami juga menerapkan wawancara kualitatif dengan nelayan dan pemangku kepentingan lokal untuk memahami secara mendalam tantangan dan aspirasi mereka dalam konteks pembangunan berkelanjutan. Hasil penelitian terhadap kelayakan ekonomi pembangunan Gedung Pusat Pelatihan dan Pemberdayaan Nelayan Berkelanjutan di Desa Kurau berdasarkan efisiensi biaya transportasi adalah layak secara ekonomi. Hal ini didasarkan beberapa parameter, yaitu besar anggaran biaya pada pembangunan gedung Pusat Pelatihan dan Pemberdayaan Nelayan Berkelanjutan di Desa Kurau sebesar Rp. 2,294,977,000. Berdasarkan analisis Kelayakan Proyek gedung Pusat Pelatihan dan Pemberdayaan Nelayan Berkelanjutan di Desa Kurau pada Net Present Value dengan suku bunga 5% mendapatkan hasil Rp 637,409,603 dan suku bunga 10% mendapatkan Rp 232,360,525, Internal Rate of Return diperoleh nilai sebesar 8,6%, dan Benefit Cost Ratio (BCR) menghasilkan nilai sebesar 1,27. Hasil nilai yang didapatkan dinyatakan layak berdasarkan analisis kelayakannya, maka dari itu proyek gedung Pusat Pelatihan dan Pemberdayaan Nelayan Berkelanjutan dapat  menguntungkan apabila dilanjutkan. Dalam perhitungan Payback Period, didapat hasil 2 maka dalam jangka waktu selama 2 tahun modal investasi dari proyek gedung Pusat Pelatihan dan Pemberdayaan Nelayan Berkelanjutan dapat dikembalikan.
OPTIMALISASI SMART ASN DALAM MENDUKUNG TRANSFORMASI BIROKRASI DI ERA DIGITAL DI PROVINSI SULAWESI UTARA
Authors: Johannes Ryan Aji
Published: January 2025

Penelitian ini bertujuan untuk menganalisis kesiapan ASN dalam menghadapi era transformasi digital, yang meliputi penguasaan teknologi serta kemampuan beradaptasi dengan perubahan dalam organisasi dan budaya kerja yang semakin kolaboratif. Salah satu aspek menarik yang diangkat adalah perbedaan tingkat kesiapan antara ASN generasi milenial dan ASN senior, topik yang masih jarang dibahas dalam penelitian sebelumnya. Kajian lebih dalam tentang kesenjangan literasi teknologi antara generasi ASN dan pengaruhnya terhadap implementasi konsep Smart ASN diharapkan dapat memberikan wawasan baru untuk mendukung pengembangan kebijakan ASN. Penelitian ini menggunakan metode deskriptif kualitatif dengan pemilihan informan melalui teknik purposive sampling. Informan dipilih berdasarkan relevansi mereka terhadap topik penelitian, termasuk ASN milenial (di bawah 40 tahun), ASN senior (di atas 40 tahun), pejabat eselon yang memimpin unit kerja, tim IT atau transformasi digital, serta akademisi dan praktisi di bidang kebijakan publik dan transformasi digital. Hasil penelitian menunjukkan bahwa pengembangan Smart ASN di Provinsi Sulawesi Utara menjadi langkah strategis dalam memperkuat transformasi birokrasi digital yang sedang digalakkan pemerintah pusat. Sebagai bagian dari upaya menciptakan birokrasi yang lebih modern dan efisien, Smart ASN berperan signifikan dalam mendukung pelaksanaan e-Government, meningkatkan kualitas pelayanan publik, dan mempercepat proses administrasi di berbagai sektor pemerintahan. Temuan utama dari penelitian ini adalah pendekatan integratif untuk menjembatani kesenjangan literasi teknologi antar generasi ASN melalui program mentoring kolaboratif antara ASN milenial dan senior di Provinsi Sulawesi Utara
THE ROLE OF LOCAL ELITE IN STRENGTHENING THE EXISTENCE OF INDIGENOUS COMMUNITIES IN BUNTU PEPASAN, NORTH TORAJA
Authors: Rompon Reinsart Sampe , Sudarmono Sudarmono
Published: January 2025

This study seeks to explain how local elites in Buntu Pepasan District support indigenous communities. This qualitative study uses in-depth interviews with official, religious, and civil elites in the local area. The research shows how each elite group supports indigenous populations. Formal elites preserve and recognize indigenous rights. Religious elites support indigenous communities morally and spiritually and uphold their values. However, civic elites and traditional leaders preserve and nurture local culture and customs. The position dimensions of each local elite reveal that they are a party that preserves cultural heritage and indigenous populations. Regarding to their reputation, local elites are trusted by the community to manage and sustain indigenous communities and use their influence to strengthen them. Furthermore, these insights can help create better indigenous community sustainability policies.
Ahead of the Count: An Algorithm for Probabilistic Prediction of Instant Runoff (IRV) Elections
Authors: Kapoor Nick , Staecker Christopher
Published: January 2025

How can we probabilistically predict the winner in a ranked-choice election without all ballots being counted? We study and introduce a novel algorithm designed to predict outcomes in Instant Runoff Voting (IRV) elections. The algorithm takes as input a set of discrete probability distributions describing vote totals for each candidate ranking and calculates the probability that each candidate will win the election. In fact, we calculate all possible sequences of eliminations that might occur in the IRV rounds and assign a probability to each. The algorithm is effective for elections with a small number of candidates with fast execution on typical consumer computers. The run-time is short enough for our method to be used for real-time election night modeling where new predictions are made continuously as more and more vote information becomes available. We demonstrate the algorithm in abstract examples, and also using real data from the 2022 Alaska elections.
Students Self-Assessing Their Class Notes Builds Critical Thinking Skills
Authors: O'Brochta William
Published: January 2025

Instructors expect students to take notes during class, but students are often unfamiliar with effective notetaking strategies. I study whether teaching students to take notes using self- assessments helps to improve student notetaking ability and aids students in understanding how to accurately evaluate their own notes. I designed a class notes assignment wherein students learned how to take notes and self-assessed their performance twice throughout an academic term. Using class notes and self-assessments from nine introduction to American politics courses with this assignment (N=194), I show that students’ notetaking ability improved during the course. Student self-assessments did tend to differ from notes grades, though the amount of improvement measured by self-assessed and graded notes was similar. The results suggest that instructors should think carefully about their expectations for student notetaking ability and consider incorporating opportunities for students to develop and assess their own notetaking strategies as part of course assignments.
A methodological scoping review on EMG processing and synergy-based results in muscle synergy studies in Parkinson’s disease
Authors: Lanzani Valentina , Brambilla Cristina , Scano Alessandro
Published: January 2025

Introduction

Parkinson’s Disease is the second most common neurodegenerative disease in the world. It affects mainly people over 65 and the incidence increases with age. It is characterized by motor and non-motor symptoms and several clinical manifestations. The most evident symptom that affects all patients with Parkinson’s Disease is the impairment of motor control, including bradykinesia, tremor, joint rigidity, and postural instability. In the literature, it has been evaluated with muscle synergies, a well-known method for evaluating motor control at the muscular level. However, few studies are available and there is still a major gap to fill to exploit the potential of the method for assessing motor control in Parkinson’s Disease, both in the understanding of physiopathology and clinical practice.

Methods

In the light of understanding and fostering future developments for the field, in this review we initially screened 212 papers on Scopus and Web of Science and selected 15 of them to summarize the main features of investigations that employed muscle synergies to analyze patients with Parkinson’s Disease. We detailed the features of the screened papers by reporting the clinical findings, a detailed report of EMG processing choices and synergy-based results.

Results

We found that synergistic control is in general altered in patients with Parkinson’s Disease, but it can improve if patients are subjected to pharmacological and rehabilitation therapies. Moreover, a further understanding of synergistic control in Parkinson’s patients is needed.

Discussion

We discuss the future developments in the field with a detailed assessment of the topic on the view of physicians, including the most promising lines of research for clinical practice and from the perspective of engineers, for methodological application of synergistic approaches.
Validation of the efficacy of the porous medium model in hemodynamic analysis of iliac vein compression syndrome
Authors: Wei Lingling , Hu Ke , Wang Jiaqiu , Zhang Shuang , Yang Xiaoxiao , Chen Yuanli , Li Chenshu , Lu Xinwu , Ye Kaichuang , Qiu Peng , Zhan Yanqing
Published: January 2025

Iliac Vein Compression Syndrome (IVCS) is a common risk factor for deep vein thrombosis in the lower extremities. The objective of this study was to investigate whether employing a porous medium model to simulate the compressed region of an iliac vein could improve the reliability and accuracy of Computational Fluid Dynamics (CFD) analysis outcomes of IVCS. Pre-operative Computed Tomography (CT) scan images of patients with IVCS were utilized to reconstruct models illustrating both the compression and collateral circulation of the iliac vein. A porous medium model was employed to simulate the compressed region of the iliac vein. The agreements of times to peak between discrete phase particles in CFD analysis and contrast agent particles in Digital Subtraction Angiography (DSA) were compared. Furthermore, comparisons were made between the CFD analysis results that incorporated the porous media and those that did not. The results revealed that in the CFD analysis incorporating the porous media model, more than 80% of discrete phase particles reached the inferior vena cava via collateral circulation. Additionally, the concentration variation curve of discrete phase particles demonstrated a high concordance rate of 92.4% compared to that obtained in DSA. In comparison to CFD analysis conducted without the porous medium model, the incorporation of the porous medium model resulted in a substantial decrease in blood flow velocity by 87.5% within the compressed region, a significant increase in pressure gradient of 141 Pa between the inferior vena cava and left iliac vein, and a wider distribution of wall shear stress exceeding 2.0 Pa in collateral vessels rather than in the compressed region. The study suggests that the introduction of a porous medium model improves the hemodynamic analysis of patients with IVCS, resulting in a closer alignment with clinical observations. This provides a novel theoretical framework for the assessment and treatment of patients with IVCS.
A cost–benefit analysis of the production system with improved and climate-resilient sorghum varieties in southern Mali
Authors: Coulibaly Adama B. , Badolo Félix , Yila Jummai O. , Koné Bourema , Nebié Baloua , Worou Nadine , Jumbo Macdonald Bright , Savadogo Kimseyinga
Published: January 2025

Given the persistently low adoption rate of improved sorghum varieties over decades, it is relevant to assess whether it is profitable or not to grow these varieties in Mali. Over the past years, little evidence has demonstrated the profitability analysis as decision-support information regarding the adoption of improved sorghum varieties. This study used cost-benefit analysis to assess the profitability of two Improved and Climate-Resilient Sorghum Varieties (ICRSVs), “Soubatimi and Tiandougou-coura” compared to the “Local” ones, using three years of average yield data (2017, 2018, and 2020) in Sikasso region, Mali. The objective was to perform a consistent cost-benefit analysis through net income, cost-benefit ratio, and gross profit margin. The study used a farm partial budget framework, sensitivity analysis, and stochastic dominance analysis methods. A final sample of 31 farmers’ on-farm trials under the fertiliser package of “100 kg complex cereal and 50 kg urea” per hectare was held as the agronomic package. The key findings showed that both varieties were profitable, with 79,661 CFA (123.56 USD) and 45,073 CFA (69.91 USD) average net incomes corresponding to 1.54 and 1.32 CBR, and 34 and 24 percents average gross profit margins, respectively, while growing the “local” varieties was not profitable, with an average loss of 12,113 CFA (18.79 USD) with 0.91 CBR and 10 percent average gross profit margin. In light of these results, the study suggests a large dissemination of the ICRSVs in Mali. Policy-makers should facilitate the implementation of outreach programs to inform smallholder sorghum farmers on the ICRSVs’ traits and profitability information as decision support tool for a larger adoption.
Petrogenesis of REE-rich two-mica granite from the Indosinian Xiekeng pluton in South China Block with implications for REE metallogenesis
Authors: Zhang Defu , Lv Tingting , Wang Xiangaung , Cao Mingxuan , Chen Xiquan , Zhang Yongwen , Gong Liangxin
Published: January 2025

The Xiekeng pluton, located in Huichang County, Jiangxi Province, is primarily composed of two-mica monzogranite. The rock features high contents of SiO2 (71.3–77.73 wt%), K2O (4.42–5.62 wt%), K2O/Na2O (1.36–1.87), and with an A/CNK value of 1.11–1.27, a differentiation index (DI) of 90.28–94.47, zircon saturation temperatures of 780°C–806°C, and K/Rb, Nb/Ta, and Zr/Hf ratios of 8.40–11.04, 2.38–9.24, and 25.42–35.37, respectively. It also contains peraluminous minerals such as muscovite, classifying it as a highly fractionated S-type granite. The total rare earth element (ΣREY = ΣREE + Y) contents range from 224.7 to 353.12 ppm, with a relative enrichment in light rare earth elements (ΣLREE/ΣHREY) of 1.55–5.36, and significant fractionation between light and heavy rare earth elements with (La/Yb)N = 3.36–18.48, and pronounced negative Eu anomalies (Eu/Eu* = 0.08–0.41). Zircon U–Pb dating ages of two-mica monzogranite samples are 241.2 ± 1.8 Ma and 238.3 ± 1.7 Ma, belonging to the Middle Triassic. Zircon εHf(t) values range from −14.93 to −9.12, with depleted mantle model ages (TDM2) of 1.86–2.03 Ga, and whole-rock Nd isotopic model ages (TDM2) are 1.90–1.93 Ga, indicating a source primarily from partial melting of Proterozoic continental crustal clay-rich mudstones. Based on muscovite chemistry, the average formation pressure of the Xiekeng pluton is calculated to be 8.35 kbar (∼30 km paleodepth). This suggests the pluton formed through deep melting and intrusion under a thickened crustal compressional tectonic setting. The Xiekeng pluton is rich in total rare earth elements, with abundant rare earth minerals such as apatite, monazite, xenotime, fluocerite, and bastnäsite, showing geochemical characteristics similar to those of typical Indosinian ion-adsorption REE deposit host rocks, indicating potential for the formation of ion-adsorption REE deposits.
Neuropsychological outcome of indoor rehabilitation in post-COVID-19 condition—results of the PoCoRe study
Authors: Jöbges Michael , Tempfli Melanie , Kohl Christoph , Herrmann Christoph , Kelm Stefan , Kupferschmitt Alexa , Montanari Ida , Walter Nike , Suetfels Gerhard , Loew Thomas , Köllner Volker , Hinterberger Thilo
Published: January 2025

Background

Post COVID-19 condition (PCC) is increasingly recognized as a debilitating condition characterized by persistent symptoms following SARS-CoV-2 infection. Neuropsychological deficits, including cognitive impairments and fatigue, are prevalent in individuals with PCC. The PoCoRe study aimed to evaluate the burden of neuropsychological deficits in PCC patients undergoing multidisciplinary indoor rehabilitation and to describe possible changes in this symptomatology.

Methods

The PoCoRe study, a prospective, non-randomized, controlled longitudinal study, recruited PCC patients from six German indoor rehabilitation centers. Eligible participants underwent comprehensive neuropsychological assessments at admission and discharge. Various measures were employed, including the fatigue scale for motor functioning and cognition (FSMC), the Test Battery for Attention (TAP) and the Montreal Cognitive Assessment (MoCA).

Results

Out of the 1,086 recruited participants, a total of N = 701 participants were included in the main data analysis. The prevalence of fatigue on admission was high (84.6%) and decreased significantly by discharge (77.4%), with a mild effect size. Reaction times on the alertness subtest were abnormal in 70% of patients on admission and 50% on discharge. Sustained attention was abnormal in 55% of patients on admission, decreasing to 43% on discharge. These differences were significant with mild effect sizes. Furthermore, of the 27% of participants with pathological MoCA scores at admission, 63% improved to normative levels during rehabilitation, indicating a significant treatment effect (p ≤ 0.001). However, the MoCA demonstrated limited sensitivity in detecting attention deficits.

Conclusion

The PoCoRe study highlights the high prevalence of neuropsychological deficits and fatigue in PCC patients, with notable improvements observed following multidisciplinary rehabilitation. Challenges remain in accurately identifying and addressing these deficits, underscoring the importance of comprehensive neuropsychological assessment and tailored rehabilitation interventions. Further research is warranted to optimize screening tools and enhance neuropsychological care for PCC patients in both rehabilitation and outpatient settings.
Retrospective analysis of amantadine response and predictive factors in intensive care unit patients with non-traumatic disorders of consciousness
Authors: Blum Corinna , Single Constanze , Laichinger Kornelia , Hofmann Anna , Rattay Tim W. , Adeyemi Kamaldeen , Riessen Reimer , Haap Michael , Häberle Helene , Ziemann Ulf , Mengel Annerose , Feil Katharina
Published: January 2025

Background

Disorders of consciousness (DoC) in non-traumatic ICU-patients are often treated with amantadine, although evidence supporting its efficacy is limited.

Methods

This retrospective study analyzed non-traumatic DoC-patients treated with amantadine between January 2016 and June 2021. Data on patient demographics, clinical characteristics, treatment specifications, and outcomes were extracted from electronic medical records. Patients were classified as responders if their Glasgow Coma Scale (GCS) improved by ≥3 points within 5 days. Good outcome was defined as a modified Rankin Scale (mRS) of 0–2. Machine learning techniques were used to predict response to treatment.

Results

Of 442 patients (mean age 73.2 ± 10.7 years, 41.0% female), 267 (60.4%) were responders. Baseline characteristics were similar between groups, except that responders had lower baseline GCS (7 [IQR 5–9] vs. 8 [IQR 5–10], p = 0.030), better premorbid mRS (2 [IQR 1–2] vs. 2 [IQR 1–3], p < 0.001) and fewer pathological cerebral imaging findings (45.7% vs. 61.1%, OR 0.56, 95% CI: 0.36–0.86, p = 0.008). Responders exhibited significantly lower mortality at discharge (13.5% vs. 27.4%, OR 0.41, 95% CI: 0.25–0.67, p < 0.001) and follow-up (16.9% vs. 32.0%, OR 0.43, 95% CI: 0.24–0.77, p = 0.002). Good outcomes were more frequent in responders at follow-up (4.9% vs. 1.1%, OR 6.14, 95% CI: 1.35–28.01, p = 0.004). In multivariate analysis higher premorbid mRS (OR 0.719, 95% CI 0.590–0.875, p < 0.001), pathological imaging results (OR 0.546, 95% CI 0.342–0.871, p = 0.011), and experiencing cardiac arrest (OR 0.542, 95% CI 0.307–0.954, p = 0.034) were associated with lower odds of response. Machine learning identified key predictors of response, with the Stacking Classifier achieving the highest performance (accuracy 64.5%, precision 66.6%, recall 64.5%, F1 score 61.3%).

Conclusion

This study supports the potential benefits of intravenous amantadine in non-traumatic DOC-patients. Higher premorbid mRS, and pathological cerebral imaging were key predictors of non-response, offering potential avenues for patient selection and treatment customization. Findings from this study informed the design of our ongoing prospective study, which aims to further evaluate the long-term efficacy of amantadine.
Bicycle-inspired simple balance control method for quadruped robots in high-speed running
Authors: Hattori Shoei , Suzuki Shura , Fukuhara Akira , Kano Takeshi , Ishiguro Akio
Published: January 2025

This paper explores the applicability of bicycle-inspired balance control in a quadruped robot model. Bicycles maintain stability and change direction by intuitively steering the handle, which induces yaw motion in the body frame and generates an inertial effect to support balance. Inspired by this balancing strategy, we implemented a similar mechanism in a quadruped robot model, introducing a yaw trunk joint analogous to a bicycle’s steering handle. Simulation results demonstrate that the proposed model achieves stable high-speed locomotion with robustness against external disturbances and maneuverability that allows directional changes with only slight speed reduction. These findings suggest that utilizing centrifugal force plays a critical role in agile locomotion, aligning with the movement strategies of cursorial animals. This study underscores the potential of bicycle balance control as an effective and straightforward control approach for enhancing the agility and stability of quadruped robots as well as potentially offering insights into animal motor control mechanisms for agile locomotion.