bluuebunny/crossref_metadata_2025 huggingface dataset:
A Framework of Structural Damage Detection for Civil Structures Using Fast Fourier Transform and Deep Convolutional Neural Networks
Authors: He Yingying , Chen Hongyang , Liu Die , Zhang Likai
Published: October 2021

In the field of structural health monitoring (SHM), vibration-based structural damage detection is an important technology to ensure the safety of civil structures. By taking advantage of deep learning, this study introduces a data-driven structural damage detection method that combines deep convolutional neural networks (DCNN) and fast Fourier transform (FFT). In this method, the structural vibration data are fed into FFT method to acquire frequency information reflecting structural conditions. Then, DCNN is utilized to automatically extract damage features from frequency information to identify structural damage conditions. To verify the effectiveness of the proposed method, FFT-DCNN is carried out on a three-story building structure and ASCE benchmark. The experimental result shows that the proposed method achieves high accuracy, compared with classic machine-learning algorithms such as support vector machine (SVM), random forest (RF), K-Nearest Neighbor (KNN), and eXtreme Gradient boosting (xgboost).
Decision Problem on Imperfect Inspections Combined under Two-Stage Inspection Policy
Authors: Jodejko-Pietruczuk Anna
Published: October 2021

Although one can presently observe great development in the methods for diagnosing conditions of technical systems, inspections which are not 100% accurate are still common in industry. If there are multiple available inspection methods which differ in accuracy of diagnosis, cost, or testing time, the answer for the question: which inspection method should be chosen is not a simple task. This paper addresses the problem and proposes a two-stage inspection policy model whose aim is to combine inspection methods that differ in their accuracy and cost features. The two-stage policy models that have been used so far in the literature assume that the second stage of an inspection is perfect, which is not always possible or profitable. For this reason, the mathematical model of the two-stage inspection policy with not-necessarily-perfect second stage is developed here, and its results are presented for the case study of diagnosing sealing in a hydraulic cylinder. The example proved that the application of mixed imperfect inspections could decrease maintenance cost, compared to the one-stage perfect inspection policy, by up to 35%. The paper also formulates a set of rules that support decision making while searching for cost-effective parameters of the two-stage policy. Their application is confirmed by a numerical example, which shows their potential in suboptimization of the proposed policy.
Analysis of Long-Term Change in the Thermal Resistance of Extruded Insulation Materials through Accelerated Tests
Authors: Choi Hyun-Jung , Ahn Hosang , Choi Gyeong-Seok , Kang Jae-Sik , Huh Jung-Ho
Published: October 2021

Two experiments were executed to examine the slice accelerated test method, suggested in ISO 11561 “Ageing of thermal insulation materials—Determination of the long-term change in thermal resistance of closed-cell plastics (accelerated laboratory test methods)” and to observe the changes in the thermal performance of insulation material over time by the real-time ageing process. The accelerated test method was conducted for 120 consecutive days using 10 mm thick-sliced specimens, which were sampled from a 50 mm thick plate body. The real-time ageing process was performed for 5000 consecutive days under constant temperature and relative humidity conditions as of 20 ± 5 °C and 50 ± 5% without any slicing. Degradation of thermal performance was shown to be stabilized at around 38 to 41% down from the initial values, which were correspondent with the approximately 10 days after the initial time. The real-time ageing process revealed similar degradation levels at around 130 days after the starting point. Converting the results using the scaling method specified in ISO 11561, the change was found in the range of 37 to 41% for the thermal resistance after 25 years and of 30 to 38% for the 25-year-average thermal resistance, respectively. Within the 10% error range, both the accelerated method and real-time ageing resulted in a similar level of degradation. Consequently, it was our observation that the slice accelerated test was quite enough to predict the practical degradation of insulation materials with at least 90% of accuracy under the specified time duration, temperature and thickness satisfactions.
Machine Learning-Based Front Detection in Central Europe
Authors: Bochenek Bogdan , Ustrnul Zbigniew , Wypych Agnieszka , Kubacka Danuta
Published: October 2021

Extreme weather phenomena such as wind gusts, heavy precipitation, hail, thunderstorms, tornadoes, and many others usually occur when there is a change in air mass and the passing of a weather front over a certain region. The climatology of weather fronts is difficult, since they are usually drawn onto maps manually by forecasters; therefore, the data concerning them are limited and the process itself is very subjective in nature. In this article, we propose an objective method for determining the position of weather fronts based on the random forest machine learning technique, digitized fronts from the DWD database, and ERA5 meteorological reanalysis. Several aspects leading to the improvement of scores are presented, such as adding new fields or dates to the training database or using the gradients of fields.
Sex Hormone-Binding Globulin (SHBG) in Cerebrospinal Fluid Does Not Discriminate between the Main FTLD Pathological Subtypes but Correlates with Cognitive Decline in FTLD Tauopathies
Authors: Campo Marta del , Pijnenburg Yolande A. L. , Chen-Plotkin Alice , Irwin David J. , Grossman Murray , Twaalfhoven Harry A. M. , Hu William T. , Meeter Lieke H. , van Swieten John , Vermunt Lisa , Martens Frans , Heijboer Annemieke C. , Teunissen Charlotte E.
Published: October 2021

Biomarkers to discriminate the main pathologies underlying frontotemporal lobar degeneration (FTLD-Tau, FTLD-TDP) are lacking. Our previous FTLD cerebrospinal fluid (CSF) proteome study revealed that sex hormone-binding globulin (SHBG) was specifically increased in FTLD-Tau patients. Here we investigated the potential of CSF SHBG as a novel biomarker discriminating the main FTLD pathological subtypes. SHBG was measured in CSF samples from patients with FTLD-Tau (n = 23), FTLD-TDP (n = 29) and controls (n = 33) using an automated electro-chemiluminescent immunoassay. Differences in CSF SHBG levels across groups, as well as its association with CSF YKL40, pTau181/total-Tau ratio and cognitive function were analyzed. CSF SHBG did not differ across groups, though a trend towards elevated levels in FTLD-Tau cases compared to FTLD-TDP and controls was observed. CSF SHBG levels were not associated with either CSF YKL40 or the p/tTau ratio. They, however, inversely correlated with the MMSE score (r = −0.307, p = 0.011), an association likely driven by the FTLD-Tau group (r FTLD-Tau = −0.38; r FTLD-TDP = −0.02). CSF SHBG is not a suitable biomarker to discriminate FTLD-Tau from FTLD-TDP.
A Pathogenic Presenilin-1 Val96Phe Mutation from a Malaysian Family
Authors: Bagyinszky Eva , Ch’ng Gaik-Siew , Chan Mei-Yan , An Seong Soo A. , Kim SangYun
Published: October 2021

Presenilin-1 (PSEN1) is one of the causative genes for early onset Alzheimer’s disease (EOAD). Recently, emerging studies have reported several novel PSEN1 mutations among Asians. In this study, a PSEN1 Val96Phe mutation was discovered in two siblings from Malaysia with a strong family history of disease. This is the second report of PSEN1 Val96Phe mutation among EOAD patients in Asia and in the world. Patients presented symptomatic changes in their behaviors and personality, such as apathy and withdrawal in their 40s. Previous cellular studies with COS1 cell lines revealed the mutation increased the amyloid-β42 (Aβ42) productions. In the present study, whole-exome sequencing was performed on the two siblings with EOAD, and they were analyzed against the virtual panel of 100 genes from various neurodegenerative diseases. In silico modeling was also performed on PSEN1 Val96Phe mutation. This mutation was located on the first transmembrane helix of PSEN1 protein, resulting significant intramolecular stresses in the helices. This helical domain would play a significant role in γ-secretase cleavage for the increased Aβ42 productions. Several other adjacent mutations were reported in this helical domain, including Ile83Thr or Val89Leu. Our study suggested that perturbations in TMI-HLI-TMII regions could also be associated with C-terminal fragment accumulation of APP and enhanced amyloid productions.
Immune Therapies for Myelodysplastic Syndromes and Acute Myeloid Leukemia
Authors: Kapoor Sargam , Champion Grace , Basu Aparna , Mariampillai Anu , Olnes Matthew J.
Published: October 2021

Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are hematologic malignancies arising from the bone marrow. Despite recent advances in treating these diseases, patients with higher-risk MDS and AML continue to have a poor prognosis with limited survival. It has long been recognized that there is an immune component to the pathogenesis of MDS and AML, but until recently, immune therapies have played a limited role in treating these diseases. Immune suppressive therapy exhibits durable clinical responses in selected patients with MDS, but the question of which patients are most suitable for this treatment remains unclear. Over the past decade, there has been remarkable progress in identifying genomic features of MDS and AML, which has led to an improved discernment of the molecular pathogenesis of these diseases. An improved understanding of immune and inflammatory molecular mechanisms of MDS and AML have also recently revealed novel therapeutic targets. Emerging treatments for MDS and AML include monoclonal antibodies such as immune checkpoint inhibitors, bispecific T-cell-engaging antibodies, antibody drug conjugates, vaccine therapies, and cellular therapeutics including chimeric antigen receptor T-cells and NK cells. In this review, we provide an overview of the current understanding of immune dysregulation in MDS and AML and an update on novel immune therapies for these bone marrow malignancies.
Loganin Ameliorates Painful Diabetic Neuropathy by Modulating Oxidative Stress, Inflammation and Insulin Sensitivity in Streptozotocin-Nicotinamide-Induced Diabetic Rats
Authors: Cheng Yu-Chi , Chiu Yu-Min , Dai Zen-Kong , Wu Bin-Nan
Published: October 2021

Loganin is an iridoid glycoside with antioxidant, anti-inflammatory, glucose-lowering activities which may address the pathological mechanisms of painful diabetic neuropathy (PDN) related to inflammation, oxidative stress, and hyperglycemia. This study investigated the underlying mechanisms of action of loganin on PDN. The in vivo model of PDN was established by streptozotocin-nicotinamide (STZ-NA) induction in Sprague Dawley (SD) rats. Subsequently, loganin (5 mg/kg) was administered by daily intraperitoneal injection. High-glucose stimulated human SH-SY5Y cells co-incubated with loganin were used to mimic the in vitro model of PDN. Loganin improved PDN rats’ associated pain behaviors (allodynia and hyperalgesia), insulin resistance index (HOMA-IR), and serum levels of superoxide dismutase (SOD), catalase and glutathione. Loganin also reduced pain-associated channel protein CaV3.2 and calcitonin gene-related peptide (CGRP) in the surficial spinal dorsal horn of PDN rats. Loganin inhibited oxidative stress and NF-κB activation and decreased the levels of mRNA and protein of proinflammatory factors IL-1β and TNF-α. Moreover, loganin attenuated insulin resistance by modulating the JNK-IRS-1 (insulin receptor substrate-1)-Akt-GSK3β signaling pathway in PDN rats. These results suggested that loganin improved PDN-mediated pain behaviors by inhibiting oxidative stress-provoked inflammation in the spinal cord, resulting in improved neuropathic pain.
Antioxidant and Antiinflammatory Effects of Epilobium parviflorum, Melilotus officinalis and Cardiospermum halicacabum Plant Extracts in Macrophage and Microglial Cells
Authors: Merighi Stefania , Travagli Alessia , Tedeschi Paola , Marchetti Nicola , Gessi Stefania
Published: October 2021

Background: We investigated the phenolic content characterizing different plant extracts from Epilobium parviflorum, Cardiospermum halicacabum, and Melilotus officinalis, their antioxidant, antiinflammatory effects, and their mechanism of action. Methods: plant samples were macerated in 40% ethanol or hot/ cold glycerate and assessed for polyphenols content. The antioxidant activity was investigated by DPPH radical scavenging assay and H2DCFDA test in LPS-stimulated RAW264.7 macrophages and N9 microglial cells. MTS experiments and antiinflammatory properties verified cellular toxicity through NO assay. Interaction with A2A adenosine receptors was evaluated through binding assays using [3H]ZM241385 radioligand. Results: Polyphenols were present in 40% ethanol plant extract, which at 0.1–10 µg/µL achieved good antioxidant effects, with a DPPH radical scavenging rate of about 90%. In LPS-stimulated cells, these plant extracts, at 1μg/μL, did not affect cell vitality, displayed significant inhibition of H2DCFDA and NO production, and inhibited ZM 241385 binding in CHO cells transfected with A2A receptors. RAW 264.7 and N9 cells presented a density of them quantified in 60 ± 9 and 45 ± 5 fmol/mg of protein, respectively. Conclusion: Epilobium parviflorum, Cardiospermum halicacabum, and Melilotus officinalis extracts may be considered a source of agents for treating disorders related to oxidative stress and inflammation.
Improved Oxidation and Hot Corrosion Resistance of 1Cr11Ni2W2MoV Stainless Steel at 650 °C by a Novel Glass-Ceramic Coating
Authors: Chen Ken , Lin Jiewei , Li Wenfang , Zhu Wen , Li Kang , Yi Aihua , Hu Shaodong , Chen Minghui , Wang Fuhui
Published: October 2021

A novel glass-ceramic coating was applied onto the 1Cr11Ni2W2MoV stainless steel. The oxidation and corrosion behaviors of coated and uncoated steels were comparatively investigated in air and in the presence of NaCl + Na2SO4 eutectic deposits at 650 °C, respectively. Protective scales formed on the surface of stainless steel prevented the severe oxidation of the alloy. Catastrophic hot corrosion occurred on the steel when a salt film was attached, producing loose iron oxide layers and internal corrosion zone. The glass-ceramic coating acted as a barrier that effectively hindered the invasion of corrosive species during the oxidation and hot corrosion tests.
Multifocality and Multicentrality in Breast Cancer: Comparison of the Efficiency of Mammography, Contrast-Enhanced Spectral Mammography, and Magnetic Resonance Imaging in a Group of Patients with Primarily Operable Breast Cancer
Authors: Steinhof-Radwańska Katarzyna , Lorek Andrzej , Holecki Michał , Barczyk-Gutkowska Anna , Grażyńska Anna , Szczudło-Chraścina Joanna , Bożek Oskar , Habas Justyna , Szyluk Karol , Niemiec Paweł , Gisterek Iwona
Published: October 2021

Background: The multifocality and multicentrality of breast cancer (MFMCC) are the significant aspects that determine a specialist’s choice between applying breast-conserving therapy (BCT) or performing a mastectomy. This study aimed to assess the usefulness of mammography (MG), contrast-enhanced spectral mammography (CESM), and magnetic resonance imaging (MRI) in women diagnosed with breast cancer before qualifying for surgical intervention to visualize other (additional) cancer foci. Methods: The study included 60 breast cancer cases out of 630 patients initially who underwent surgery due to breast cancer from January 2015 to April 2019. MG, CESM, and MRI were compared with each other in terms of the presence of MFMCC and assessed for compliance with the postoperative histopathological examination (HP). Results: Histopathological examination confirmed the presence of MFMCC in 33/60 (55%) patients. The sensitivity of MG in detecting MFMCC was 50%, and its specificity was 95.83%. For CESM, the sensitivity was 85.29%, and the specificity was 96.15%. For MRI, all the above-mentioned parameters were higher as follows: sensitivity—91.18%; specificity—92.31%. Conclusions: In patients with MFMCC, both CESM and MRI are highly sensitive in the detection of additional cancer foci. Both CESM and MRI change the extent of surgical intervention in every fourth patient.
Enrichment and Gifted Education Pedagogy to Develop Talents, Gifts, and Creative Productivity
Authors: Reis Sally M. , Renzulli Sara Jane , Renzulli Joseph S.
Published: October 2021

Providing challenging and engaging learning opportunities is one way to motivate students to learn. In this article, we discuss the contributions of the gifted education field to the development of enrichment pedagogy and identify several different types of these engaging instructional strategies, including interest-based learning pedagogy, differentiation and curriculum compacting, project-based learning, open-ended choice, and the application of creative productivity to students learning. We identify this specialized pedagogy and give examples of how these exciting pedagogical strategies can be implemented in classrooms and by enrichment specialists and school counselors, both for academically talented and for all students. We conclude with a brief overview of research that demonstrates longitudinal benefits for students who are exposed to this type of teaching, suggesting positive outcomes.
Social Distance Monitoring Approach Using Wearable Smart Tags
Authors: Alhmiedat Tareq , Aborokbah Majed
Published: October 2021

Coronavirus has affected millions of people worldwide, with the rate of infected people still increasing. The virus is transmitted between people through direct, indirect, or close contact with infected people. To help prevent the social transmission of COVID-19, this paper presents a new smart social distance system that allows individuals to keep social distances between others in indoor and outdoor environments, avoiding exposure to COVID-19 and slowing its spread locally and across the country. The proposed smart monitoring system consists of a new smart wearable prototype of a compact and low-cost electronic device, based on human detection and proximity distance functions, to estimate the social distance between people and issue a notification when the social distance is less than a predefined threshold value. The developed social system has been validated through several experiments, and achieved a high acceptance rate (96.1%) and low localization error (<6 m).
Radiation Beam Pattern Control of UHF RFID Tag Antenna Design for Automotive License Plates
Authors: Chung Youchung , Berhe Teklebrhan H.
Published: October 2021

This paper presents a design of a radio frequency identification (RFID) tag antenna in the ultra-high-frequency (UHF) range, which is applicable to a vehicular license plate attached to a vehicle bumper. The main goals are to first improve the identification ratio by controlling the radiation beam pattern and, second, to control the beam direction. Since every vehicle has a license plate, the available plate structure is used to design the antenna. The shape of the tag is rectangular and has a dimension of 525 mm × 116 mm, which is smaller than the typical size of standard plates, 540 mm × 120 mm, used in Europe and Korea. The fabricated tag antenna, the license plate, and the vehicular bumper are fixed by volt and nut. For vehicle tracking and identification, RFID readers are deployed on the road side. For efficient identification, a long distance passive UHF RFID license plate with a patch antenna is proposed to provide not only line-of-sight identification but also left and right beams. Unlike the general UHF tag antennas, in this paper, the patch antenna is designed to attach to the metal part of the car, the license plate holder. The beam patterns of the RFID tag antenna can be controlled by the patch antenna parameter values. The simulation result demonstrates that the proposed UHF RFID tag antenna has a beam radiation pattern as required at 920 MHz. In addition, the estimated read range of the proposed plate meets the requirement of RFID systems.
CA-CRE: Classification Algorithm-Based Controller Area Network Payload Format Reverse-Engineering Method
Authors: Ji Cheongmin , Ko Taehyoung , Hong Manpyo
Published: October 2021

In vehicles, dozens of electronic control units are connected to one or more controller area network (CAN) buses to exchange information and send commands related to the physical system of the vehicles. Furthermore, modern vehicles are connected to the Internet via telematics control units (TCUs). This leads to an attack vector in which attackers can control vehicles remotely once they gain access to in-vehicle networks (IVNs) and can discover the formats of important messages. Although the format information is kept secret by car manufacturers, CAN is vulnerable, since payloads are transmitted in plain text. In contrast, the secrecy of message formats inhibits IVN security research by third-party researchers. It also hinders effective security tests for in-vehicle networks as performed by evaluation authorities. To mitigate this problem, a method of reverse-engineering CAN payload formats is proposed. The method utilizes classification algorithms to predict signal boundaries from CAN payloads. Several features were uniquely chosen and devised to quantify the type-specific characteristics of signals. The method is evaluated on real-world and synthetic CAN traces, and the results show that our method can predict at least 10% more signal boundaries than the existing methods.
DWSA: An Intelligent Document Structural Analysis Model for Information Extraction and Data Mining
Authors: Yue Tan , Li Yong , Hu Zonghai
Published: October 2021

The structure of a document contains rich information such as logical relations in context, hierarchy, affiliation, dependence, and applicability. It will greatly affect the accuracy of document information processing, particularly of legal documents and business contracts. Therefore, intelligent document structural analysis is important to information extraction and data mining. However, unlike the well-studied field of text semantic analysis, current work in document structural analysis is still scarce. In this paper, we propose an intelligent document structural analysis framework through data pre-processing, feature engineering, and structural classification with a dynamic sample weighting algorithm. As a typical application, we collect more than 11,000 insurance document content samples and carry out the machine learning experiments to check the efficiency of our framework. Meanwhile, to address the sample imbalance problem in the hierarchy classification task, a dynamic sample weighting algorithm is incorporated into our Dynamic Weighting Structural Analysis (DWSA) framework, in which the weights of different category tags according to the structural levels are iterated dynamically in training. Our results show that the DWSA has significantly improved the comprehensive accuracy and the classification F1-score of each category. The comprehensive accuracy is as high as 94.68% (3.36% absolute improvement) and the Macro F1-score is 88.29% (5.1% absolute improvement).
Negative symptoms in schizophrenia: clinical aspects and assessment
Authors: Munin Andrey Olegovich , Belokrylov Igor Vladlenovich
Published: October 2021

Background: negative symptoms of schizophrenia represent a major diagnostic and therapeutic challenge. They are often the first symptoms of the disease, but they are rarely the reason for seeking initial medical attention. Negative symptoms are one of the key factors determining functional outcome and leading to disability. The purpose of this review is to provide up-to-date information on the negative symptoms of schizophrenia, their clinical manifestations and methods of assessment. This information can be useful for clinicians and researchers who work with patients with schizophrenic disorders. Materials and methods: the following resources were used to search for literary sources: https://www.ncbi.nlm.nih.gov/pubmed/, https://scholar.google.ru/, https://cyberleninka.ru/. The number of sources cited is 28. Results: the development of modern assessment methods allows researchers to look at negative symptoms in a new way. It is now accepted that negative symptoms represent a two-factor model of impairment or absence of functions associated with motivation and verbal / emotional expression. Conclusion: this article is a systematic analysis of the scientific medical literature regarding negative symptoms in schizophrenia.
Clinical epidemiology in complementary medicine (discussion)
Authors: Novikov Yuriy Olegovich , Tsykunov Mikhail Borisovich , Shayakhmetov Ayrat Rafikovich
Published: October 2021

The article presents an analytical review of the literature on the application of the principles of evidence-based medicine in modern healthcare. It is noted that in some areas of medicine, scientifically based standards of treatment significantly fall behind the general trends. Complementary medicine, including osteopathy, is an important healthcare resource, the use of which is officially recognized in 94 countries around the world. However, despite certain achievements in the treatment and prevention of many chronic diseases, there are scientific articles that criticize its effectiveness. Therefore, the relevance of obtaining new, strictly evidence-based data on the impact of osteopathy on health is beyond doubt. For osteopathy, as for other types of complementary medicine, a new paradigm of evidence-based clinical research is probably needed. Three types of the organism response to treatment — instant, fast and delayed — are identified.
Possibilities of high-frequency Doppler ultrasound for differential diagnosis of spondylogenic muscle-tonic pain syndromes
Authors: Andreev Vladislav Vladimirovich , Kodzaev Yuriy Kambulatovich , Sychev Aleksandr Ivanovich , Shishkin Aleksandr Vyacheslavovich , Arapov Artem Sergeevich , Andreeva Svetlana Vladimirovna
Published: October 2021

Changes in tissue perfusion parameters indicate not only a violation of systemic hemodynamics, but can also occur with local changes in the structure of the organ pathological process. Along with degenerative and dystrophic changes in the structures of the motor segment, muscle-tonic (myofascial) pains occur in a significant number of cases. The possibilities of instrumental assessment in case of local microcirculation disorders in skeletal muscle make it possible to diagnose key manifestations — to identify an area with low blood supply. Within the framework of the study, a limited area of reduced perfusion was established in myofascial pain syndrome. With the formation of a painful muscle knot, the parameter of the volumetric blood flow velocity (Qas) is 0.006±0.0005 cm³/min, while the comparison with the control points fixes the level of blood supply at 0.0046±0.0005 cm³/min (p<0.005). The method for assessing the volumetric blood flow rate in skeletal muscle allows reliably diagnosing the key symptom of myofascial syndrome — a painful muscle knot.
Pharmacogenetics of antidepressants (from history to the present)
Authors: Ilyina Elena Sergeevna , Filippova Natal’a Valer’evna , Barylnik Yulia Borisovna
Published: October 2021

Pharmacogenetics is a relatively new scientific discipline, which is currently the main tool in personalized medicine. The aim of research in this area is to identify significant genetic markers for the introduction of their accounting in routine clinical practice. Generalization of data on the patient’s phenotype should be the key to predicting the pharmacokinetics and pharmacodynamics of the drug in the body. A personalized approach based on pharmacogenetic research data in psychiatry is extremely relevant due to the high social and budgetary costs of treating mental disorders around the world. Currently, there are data on the pharmacogenetics of most modern antidepressants, however, conducting such studies in patients with depressive disorders in most cases is impossible for implementation in routine clinical practice due to the impossibility of conducting the test in the laboratory of medical organizations and the lack of specialists competent in the clinical interpretation of the results of pharmacogenetic testing.
Cooperation of subjects of the educational process in the context of project activities
Authors: Muller Olga Yurievna
Published: October 2021

The article describes the essence of the application of project-based learning from the point of view of the formation of competencies. The analysis of scientific literature on the implementation of the project method was carried out; the aspects of professional training of future teachers of the profile "Technological education" were studied. The features of the project method of teaching in the context of the discipline "Additional education for children" are presented. The purpose of the study is the theoretical substantiation of project-based education at a higher educational institution for the development of professional competencies of future pedagogues on the example of developing a practice-oriented project. The methodological basis of the research is the ideas of developmental education, competence-based and active approaches, as well as general scientific methods of comparative analysis, synthesis and generalization. The theoretical significance of the article lies in describing the content of the concept of project-based education at a higher educational institution as a purposeful interaction of subjects to create a product. A theoretical justification for the use of project-based education at a higher educational institution for the formation of competencies is presented. The practical significance of the article lies in the fact that the conclusions and provisions contained in it reveal the ways of organizing project-based education at the higher educational institution for the development of the professional qualities of students in the pedagogical field of training, while the considered preparatory stage of the practice-oriented project "NTI Lessons" clearly illustrates the presented theoretical provisions. The evaluation of the project's effectiveness is simultaneously determined through the analysis of the components of each block, which reflects the quantitative and qualitative relationship between the results of educational activities, professional education and labor activity.
Political science and digital society: some issues of modern education in higher education (experience of the EU countries)
Authors: Ustinovich Elena Stepanovna
Published: October 2021

The course of political science in higher education is often read, to a large extent, as a theoretical course and affects the study of issues and problems of the formation and development of political institutions, processes and technologies. The focus is usually on the history of politics, the state as the central institution of the political system, political parties, political consciousness, culture, political relations, etc. However, it is very important that, when studying a course in political science, listeners understand the current political processes taking place around them. Some of them are well established, democratic processes, such as the electoral process. Others are associated with the impact of modern innovation processes on the political sphere of society. And in this case, political science as a science once again demonstrates its value in an applied format. For a deep understanding of this kind of political processes, additional aggregated information is needed, knowledge that should differ in such characteristics as relevance, novelty, compliance with modern development. In the modern digital era, it is necessary to additionally acquire knowledge about the digital transformation of political institutions, processes and technologies, including types of state policy, the most important of which is social. And it's not just the digital economy. This, first of all, digitalization of public administration (State-web) — Big Date management, blockchain, etc., as well as digitalization of business — the emergence and development of digital enterprises, etc. It is obvious that the use of digital technologies will become possible for the development of predictive political science. This article is largely a translation of German publications by scientists dealing with the development of modern political science education in the countries of the European Union, in particular, in the Federal Republic of Germany. The focus is on the impact of digitalization on the teaching of theoretical and applied political science.
Socio-psychological climate in the management structure of the State Service for Combating Economic Crimes under the Government of the Kyrgyz Republic
Authors: Salmorbekova Rita Bobuevna , Karabaeva Indira Bektemirovna
Published: October 2021

This article analyzes the socio-psychological climate of the management structure of the State Service for Combating Economic Crimes under the Government of the Kyrgyz Republic, using a sociological survey. The socio-psychological interaction of the team, which in turn affects the results of production and social performance and predetermines the nature of the internal and external environment of the public service, is determined. The socio-psychological climate of the labor collective is influenced by many objective and subjective factors. Firstly, it is possible to single out the factors of the external and internal environment of this service. The factors of the external environment are identified as social, economic and political situation, level and conditions of life, culture.
Socio-psychological aspects of informational socialization of the individual in the context of digitalization of society
Authors: Ismanova Nurlan Abdrasulovna , Abylkasymova Asel Osmonbekovna
Published: October 2021

This article reveals the essence and significance of informational socialization of the youth from the point of view of their formation as individuals and identifies the socio-psychological characteristics of digital socialization of the youth in the crisis conditions of the new era. Socialization is considered as a twofold process, where the older generation and society are presented as a mediator and transmitter of social experience to generations, and an individual, as an adopter of the experience that finds its characteristic place in society, becomes a capable participant in social interaction. The methodological basis of the study was the theoretical provisions of foreign and Russian scientists, general scientific methods of analysis, synthesis and generalization of the material. The work analyzes the scientific literature and studies the arguments of scientists on this issue. The peculiarity of informational socialization of the individual in the crisis conditions of Kyrgyzstan is noted. The theoretical significance of the article lies in the revealing of the content of informational socialization of the individual, the development of the policy of «human capital», the recognition of the social potential of the youth as a value of society, the development of effective mechanisms for the socialization of the youth in the context of the transition to an information society and digitalization of communications, which are considered new topical trends in modern science and are the goal of the work of the authors of the article. The practical significance of the article lies in the fact that the conclusions and provisions contained in it reveal the ways of the phased implementation of targeted youth development programs, which reflects the quantitative and qualitative relationship between the results of educational activities, vocational education, labor activity and the future well-being of the individual.
PENERAPAN PERATURAN MENTERI HUKUM DAN HAM NO 32 TAHUN 2018 PADA UNIT PELAKSANA TEKNIS PEMASYARAKATAN
Authors: Santoso Danang Wisnu
Published: October 2021

The purpose of this paper is to examine the application of the regulation of the Minister of Law and Human Rights No. 32 of 2018 concerning the treatment of elderly prisoners and convicts, where the regulation can be used as a reference for the Correctional Technical Implementation Unit to carry out services for elderly inmates.The research method uses a qualitative descriptive approach. trying to explain by describing the conditions that exist in the Technical Implementing Unit in providing services to elderly prisoners and comparing it with PermenKUMHAM No. 32 of 2018. The results of the study explain that the implementation of PermenKumHAM No. 32 of 2018 in the Correctional Technical Implementation Unit has not been evenly implemented. , but that does not mean that it is not carried out at all in the technical implementing unit.
Analisis Korelasi Pre Eklampsia Dalam Kehamilan Dengan Kejadian Asfiksia Neonatorum
Authors: Nurul Auliya Kamila
Published: October 2021

Asphyxia neonatorum is the failure of the newborn to breathe spontaneously and regularly, causing further disturbances. The onset of asphyxia in infants with pre-eclamptic mothers is due to high blood pressure causing reduced blood delivery to the placenta, this will reduce the supply of oxygen and food for the baby. As a result, the baby's development is slow, and intrauterine hypoxia occurs. The purpose of this study was to determine the correlation between pre-eclampsia in pregnancy and the incidence of asphyxia neonatorum in the NICU Room of the Mataram City Hospital, NTB in 2020. The research method used in this study was analytical correlational with a case control design with a retrospective time approach. The population is the data of all women giving birth in the NICU Room of Mataram City Hospital in 2020 as many as 1,098 people. The sampling technique used was systematic random sampling so that the number of samples obtained was 124 samples. The tools used are medical records. The statistical analysis used was the chi square test. The results showed that of the 124 samples studied, the neonatal asphyxia infants in mothers with pre-eclampsia were 39 (62.9%) compared to 23 (37.1%) non-preeclamptic mothers, the results of the probability value (p value) = 0.000 <α 0.05, by itself Ho is rejected, which means that there is a relationship between pre-eclampsia and newborn asphyxia at the Mataram City Hospital. So it can be concluded that, mothers who experience preeclampsia tend to have neonatal asphyxia. It is recommended that health workers at the Mataram City Hospital to further improve the quality of health services to the community, especially mothers giving birth, to keep their health checked at the health service place so that the risk of pre-eclampsia can be prevented.
TINDAK TUTUR BAHASA DALAM GENDER DI SDK HARAPAN DENPASAR KELAS V
Authors: I Gede Neil Prajamukti Wardhana
Published: October 2021

ABSTRACTSocial beings do not live alone, depend on other people and always need it. Yule (2016: 118) stated that the term of speech act used to describe the actions like “asking” “commanding” “asking question” or “giving information”. This research was descriptive analysis research that finding speech act and also related with gender by student and teacher in the class. The sample of this research was grade 5A SDK Harapan, Denpasar in the academic year 2017/2018. The method of collecting data of this research was qualitative approach in the study case and also by observation method to students and teacher in elementary school. Data that collected was written conversation and sentence by students and types of speech act in gender. The results of this research was finding conversation and sentence happened in the class and compatible types of speech act and related with gender. One of these results of in this research was “indah banget ini bu” in terms of compliments (Kuntjara, 2003). Based on these results of this research is needed the concern from the teacher and school in doing the speech act and also in gender happening in the class as well as school.

Keywords: language, speech act and gender
ASIMILASI BUDAYA BALI DALAM GEREJA DI KABUPATEN BADUNG
Authors: Putu Chrisma Dewi  , Putu Chris Susanto
Published: October 2021

AbstrakPenelitian ini bertujuan untuk menggali bentuk-bentuk asimilasi budaya yang terjadi di Gereja protestan dan Katholik termasuk di dalmnya menggali bagaimana peran asimilasi tersebut dalam pemertahanan budaya dan bahasa. Penelitian ini bersifat deskriptif-kualitatif dan melibatkan dua gereja yang merupakan gereja awal dan mempengaruhi keberadaan gereja-gereja berikutnya di Bali. Wawancara dan studi pustaka dilakukan untuk menemukan jawaban untuk setiap permasalahan dalam penelitian ini. Asimilasi budaya dalam Gereja Protestan dan Katholik di Kabupaten Badung terjadi pada tataran bangunan, pakaian, tata ibadah, dan kegiatan kemasyarakatan. Asimilasi ini berpreran dalam pelestarian bahasa dan budaya Bali, secara tidak langsung bangunan fisik, tata keagamaan serta kegiatan-kegiatan kemasyarakatan yang mengusung budaya Bali akan mempengaruhi generasi muda untuk mempertahankan nila-nilai kebudayaan Bali.

Kata kunci: gereja, asimilasi, budaya
Multiply Warped Product Generalized Semi-Invariant Submanifolds
Authors: Traore Moctar , Taştan Hakan Mete , Gerdan Aydın Sibel
Published: October 2021

We define generalized semi-invariant submanifolds in locally product Riemannian manifolds. Then we study multiply warped product generalized semi-invariant submanifolds in the same structure. We give an existence theorem for such submanifolds. We also give necessary and sufficient conditions for such a submanifold to be a multiply direct product submanifold. Moreover, we establish a general inequality for such submanifolds.
Generation of high-pH groundwaters and H2 gas by groundwater–kimberlite interaction, northeastern Ontario, Canada
Authors: Sader Jamil A. , Harrison Anna L. , McClenaghan M. Beth , Hamilton Stewart M. , Clark Ian D. , Sherwood Lollar Barbara , Leybourne Matthew I.
Published: October 2021

We report new isotopic data for H2 and CH4 gases and Sr for groundwater collected from Jurassic Kirkland Lake kimberlites in northern Ontario, Canada. Groundwaters interacting with kimberlites have elevated pH (up to 12.4), are reducing (Eh as low as the H2-H2O couple), are dominated by OH− alkalinity, and have non-radiogenic (mantle) 87Sr/86Sr values (∼0.706–0.707). Most significantly, the highest pH groundwaters have low Mg, high K/Mg, and are associated with abundant reduced gases (H2 ± CH4). Open system conditions favor higher dissolved inorganic carbon and CH4 production, whereas under closed system conditions low DIC, elevated OH− alkalinity, and H2 production are enhanced. Hydrogen gas is isotopically depleted (δ2HH2 = −771 to −801‰), which, combined with δ2HH2O, yields geothermometry temperatures of serpentinization of 5–25 °C. Deviation of H2-rich groundwaters (by up to 10‰) from the meteoric water line is consistent with Rayleigh fractionation during reduction of water to H2. Methane is characterized by δ13CCH4 = −35.8 to −68‰ and δ2HCH4 = −434‰. The origin of CH4 is inconclusive and there is evidence to support both biogenic and abiogenic origins. The modeled groundwater–kimberlite reactions and production of elevated concentrations of H2 gas suggest uses for diamond-production tailings, as a source of H2 for fuel cells and as a carbon sink.
Geometallurgical ore characterization of the high-grade polymetallic unconformity-related uranium deposit
Authors: Kaczowka Andrew J. , Kyser T. Kurt , Kotzer Tom G. , Leybourne Matthew I. , Layton-Matthews Daniel
Published: October 2021

Cigar Lake is a polymetallic, unconformity-related uranium deposit with complex geochemistry and mineralogy located in the eastern Athabasca Basin of northern Saskatchewan, Canada. Variable concentrations and spatial distributions of elements of concern, such as As, Mo, Ni, Co, Se, and Zr, associated with the high-grade tetravalent uranium ores [UO2+x; U(SiO4)1–x(OH)4x] present unique mining, metallurgical, and environmental challenges. Sulfide and arsenide minerals have significant control over As, Mo, Ni, Co, and Se abundances and have properties that affect element of concern mobility, thus requiring consideration during mineral processing, mine-effluent water treatment, and long-term tailings management.

The U-bearing (uraninite, coffinite) and metallic arsenide (nickeline, often called “niccolite” in the past), sulfarsenide (gersdorffite, cobaltite), and sulfide (chalcopyrite, pyrite, galena, bornite, chalcocite, sphalerite, pyrrhotite) minerals provide the main controls on the distributions of the elements of concern. Arsenic, Ni, and Co occur primarily in a reduced state as 1:1 molar ratio, Ni-Co:As, arsenide, and sulfarsenide minerals such as gersdorffite, nickeline, and cobaltite. Molybdenum occurs within molybdenite and uraninite. Selenium occurs within coffinite, sulfide, and sulfarsenide minerals. Zirconium is found within detrital zircon and coffinite.

The spatial distribution and paragenesis of U-, As-, and S-bearing minerals are a result of the elemental composition, pH, and redox conditions of early formational and later meteoric fluids that formed and have modified the deposit through access along lithostratigraphic permeability and tectonic structures. Using the holistic geometallurgical paradigm presented here, the geochemistry and mineral chemistry at Cigar Lake can be used to optimize and reduce risk during long-term mine and mill planning.
Paleoredox conditions, hydrothermal history, and target vectoring in the Macmillan Pass base-metal district, Yukon, Canada: 2 – Pyrite paragenesis and mineral chemistry
Authors: Leighton Claire , Layton-Matthews Daniel , Peter Jan M. , Gadd Michael G. , Voinot Alexandre , Leybourne Matthew I.
Published: October 2021

The MacMillan Pass district in Yukon, Canada, hosts the Tom and Jason clastic sediment-hosted Zn-Pb-Ag-(Ba) deposits. Pyrite-bearing drill core samples were collected from seven drill holes that intersected sulfide mineralization and time-stratigraphically equivalent rocks at varied spatial distances extending up to 3 km away from the deposits to assess the relative timing of pyrite mineralization and the chemistry of pyrite paragenesis. There are four pyrite morphologies: framboids and polyframboids (Py1), subhedral to euhedral inclusion-free crystals (Py2a), silicate inclusion-bearing nodules with serrated edges (Py2b), and euhedral idiomorphic overgrowths on preexisting pyrite morphologies (Py3). These morphological varieties correspond in time from syngenetic to earliest diagenetic growth (Py1), early to late diagenetic growth (Py2a, Py2b), and metamorphic crystallization and/or recrystallization of previous textural varieties (Py3). A representative subset of pyrite grains was analyzed for trace element contents and distributions by laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS). Analyses by LA-ICP-MS reveal that each textural variety of pyrite has a distinct trace element composition that also varies depending on stratigraphic unit. A suite of clastic sediment-hosted sulfide mineralization-related elements was incorporated into Py2 within sulfide mineralized units at greater abundances than that in unmineralized units (e.g., Zn, As, Pb, Tl, Bi). Lead abundances and Pb/Se and As/Mo values in pyrite are the most robust vectoring tools documented. The timing for clastic sediment-hosted Zn-Pb mineralization was syn and/or post late diagenesis (Py2b).

A Ba-enriched horizon was identified in rocks and this is interpreted to be the distal time-stratigraphic equivalent unit to Zn-Pb mineralization. The Ba-enriched horizon contains Py2 with anomalous metal (Tl, Co, Mn, Cd, Zn, Sb) contents and abundant macroscopic baryte, and it is interpreted to represent the distal expression of sulfide mineralization-forming hydrothermal activity. Four genetic models for mineralization are reviewed; however, the only model that is consistent with our whole rock and pyrite geochemistry involves venting of buoyant hydrothermal fluid, mixing with ambient seawater, and remaining or sinking into unconsolidated sediments, with lateral migration up to 2–3 km from the vent source.