bluuebunny/crossref_metadata_2025 huggingface dataset:
Orthopaedic diagnoses in patients with Klippel-Trenaunay syndrome
Authors: Schoch J. J. , Nguyen H. , Schoch B. S. , Anderson K. R. , Stans A. A. , Driscoll D. , Tollefson M.
Published: August 2019

Purpose

Klippel-Trenaunay syndrome (KTS) is a rare combined vascular malformation composed of capillary malformation, lymphatic and/or venous malformation and limb overgrowth, which commonly affects the extremities. Due to limb involvement, it is not uncommon for these patients to require referral to an orthopaedic surgeon. Herein we reviewed the prevalence of orthopaedic diagnoses in a large cohort of KTS patients and described the associated surgical interventions.

Methods

Between 1976 and 2012, 410 patients fulfilling strict criteria for KTS were evaluated at a single institution. Patient charts were reviewed for demographic information, details of the clinical evaluation, orthopaedic consultation and surgical interventions.

Results

A total of 264 of 410 patients (64%) with confirmed KTS required orthopaedic evaluation. Of these 264 patients, 84% had documented limb-length discrepancy. Other common diagnoses included: angular deformities (10%), scoliosis (9%), osteopenia/osteoporosis (7%), pathological fractures (6%), joint contracture (5%), degenerative joint disease (4%) and limb/joint pain (4%). Of the 264 patients evaluated by orthopaedic surgery, 133 patients (50.4%) underwent 169 surgeries. Surgery was most commonly performed for limb-length discrepancy (62%). Multivariable analysis confirmed an orthopaedic condition was more likely in patients with lymphatic malformation (odds ratio (OR) 3.78; p < 0.001), as well as in those with bone and/or soft-tissue hypertrophy of the lower extremity (OR 7.51; p < 0.001) or foot (OR 3.23; p < 0.001).

Conclusion

Orthopaedic conditions are common in patients with KTS and approximately 50% require surgical intervention. Those with a lymphatic malformation and/or soft-tissue hypertrophy of the lower extremity are more likely to need surgery.

Level of Evidence

Level IV, Descriptive Case Series
Paediatric anterior cruciate ligament tears: Management and growth disturbances. A survey of EPOS and POSNA membership
Authors: Accadbled F. , Gracia G. , Laumonerie P. , Thevenin-Lemoine C. , Heyworth B. E. , Kocher M. S.
Published: August 2019

Purpose

The therapeutic algorithm of paediatric anterior cruciate ligament (ACL) tears remains controversial. The primary aim of the study was to describe variations in practice patterns among European Paediatric Orthopaedic Society (EPOS) and Pediatric Orthopaedic Society of North America (POSNA) members with respect to management of ACL tears in skeletally immature patients. The secondary objective was to determine the number, type and severity of growth disturbances associated with ACL reconstruction (ACLR).

Methods

An email invitation to complete a 52-question survey was sent to all members of POSNA and EPOS. Data were collected automatically. Descriptive statistics were applied.

Results

In all, 305 (25.4%) surgeon members responded. Only 182 (60%) of the participants treated ACL injuries in skeletally immature patients and completed the survey. A total of 17% of EPOS and 70% of POSNA members recommended ACLR within three months for a prepubescent paediatric ACL tear. In total, 61% of POSNA and 83% of EPOS members recommended ACLR within three months for a pubescent paediatric ACL tear. Epiphyseal tunnels were the preferred technique in prepubescent children (43% at the tibia and 49% at the femur), while transphyseal tunnels were recommended preferentially in pubescent children (85% at the tibia and 63% at the femur). In all, 5.5% of participants reported growth disturbances after ACLR.

Conclusion

Current practice patterns across the Atlantic remain varied and controversial. Consensus remains elusive; as such, research collaboration among societies will be important to develop an evidence-based treatment algorithm. The use of transphyseal tunnels has been reinforced. The number of cases of significant growth disturbance is minimal, yet worrisome.

Level of Evidence

II
O close-up e o sujeito reinventado: À procura do personagem de cinema
Authors: Leal João Vitor
Published: August 2019

Este artigo pretende investigar o primeiro cinema em busca de marcas da “invenção” do personagem cinematográfico e, de modo correlato, da “invenção” do ator de cinema. Analisaremos diversas estratégias de enunciação e de figuração que revestem o corpo filmado de sua carga narrativa, tornando significativas suas aparições no decorrer do filme. Dentre essas estratégias, ressaltaremos o plano aproximado do rosto do ator – de  Chapeaux à transformations (Lumière, 1895) a Fantômas (Feuillade, 1913), o close-up se mostra a principal ferramenta que permite ao espectador antecipar e projetar na figura humana uma identidade individual dotada de certa consistência psicológica e apta a desempenhar as funções narrativas que passam a ser exigidas pelos filmes. Veremos todavia que, apesar de sua essencial contribuição para o processo de “integração narrativa”, o close-up também preserva o rosto como uma “atração” à parte. Tal força atracional, já presente em obras de Méliès (Le roi du maquillage, 1904) e A. E. Weed (Photographing a female crook e Subject for the rogue’s gallery, 1904), chega renovada ao momento contemporâneo através de filmes que, investindo em metamorfoses e multiplicações dos personagens, complicam a relação entre corpo e identidade. Assim, o retorno ao close-up no primeiro cinema se revela crucial para a compreensão das origens e complexidades do personagem cinematográfico para além das órbitas da literatura e do teatro.
SOCIOLOGY OF KNOWLEDGE IN TIMES DETERMINED BY KNOWLEDGE
Authors: BARANOWSKI MARIUSZ
Published: August 2019

This article is a selective introduction to the description and characterization of the changes that have occurred in the sociology of knowledge since the publication of Max Scheler’s book in 1924 to contemporary times, most often conceptualized by the term knowledge society. A brief review of the main threads in the field of sociology of knowledge was intended to draw attention to the theoretical and practical advantages of particular approaches, as well as their disadvantages, resulting in a trivial study of the phenomenon of knowledge in question. The descriptive character of this article also allowed for a number of systematizations within specific approaches (e.g. Michel Foucault) and within a broad perspective of the knowledge phenomenon.
THE COMMUNICATIVE TURN IN GERMAN SOCIOLOGY OF KNOWLEDGE
Authors: KNOBLAUCH HUBERT
Published: August 2019

In this paper, I want to start with a short sketch on the development of the German sociology of knowledge which has been quite successful in the last decade. Thus success is very much due to its orientation to the “Social Construction of Reality”. Its reception led first to research on language and then to a turn from language to communication which led into what came to be called communicative constructivism. This turn took very much an empirical form, so that we shall sketch the programme implicit in the empirical movement leading to communicative constructivism. Before we address the general sociological background for this movement, i.e. communication society and refiguration, we shall outline its major theoretical features which distinguish communicative constructivism from its predecessor, social constructivism.
Integrated Subsurface Temperature Modeling beneath Mt. Lawu and Mt. Muriah in The Northeast Java Basin, Indonesia
Authors: B. Nurhandoko Bagus Endar , Kurniadi Rizal , Susilowati  , Triyoso Kaswandhi , Widowati Sri , Asmara Hadi M. Rizka , Abda M. Rizal , K. Martha Rio , Fatiah Elfa , Rizal Komara Insan
Published: August 2019

The subsurface temperature has many impacts on geological phenomena such as hydrocarbon generation, geothermal energy, mineralization, and geological hazards. The Northeast Java Basin has various interesting phenomena, such as many oil fields, active faults, mud eruptions, and some active and dormant volcanoes. We measured temperature data from tens of wells along a 130 km survey line with an average spacing of 5 km. We also measured the thermal conductivity of rocks of various lithologies along the survey line to provide geothermal heat flow data. We propose integrated modeling for profiling the subsurface temperature beneath the survey line from Mt. Lawu to Mt. Muriah in the Northeast Java Basin. The modeling of subsurface temperature integrates various input data such as a thermal conductivity model, surface temperature, gradient temperature, a geological model, and geothermal heat flow. The thermal conductivity model considers the subsurface geological model. The temperature modeling uses the finite difference of Fourier’s law, with an input subsurface thermal conductivity model, geothermal heat flow, and surface temperature. The subsurface temperature profile along with survey line shows some interesting anomalies which correlate with either subsurface volcanic activity or the impact of fault activity.
Effects of a 12-Week Resistance Training Program on Arterial Stiffness: A Randomized Controlled Trial
Authors: Werner Timothy J. , Pellinger Thomas K. , Rosette Vincent D. , Ortlip Austin T.
Published: August 2019

Werner, TJ, Pellinger, TK, Rosette, VD, and Ortlip, AT. Effects of a 12-week resistance training program on arterial stiffness: a randomized controlled trial. J Strength Cond Res 35(12): 3281–3287, 2021—Arterial stiffness is an indicator of disease and is an independent predictor of cardiovascular events. Some reports indicate that resistance training increases indices of arterial stiffness, whereas others report no association. This study sought to determine the association between 2 common resistance training models and indices of arterial stiffness. We recruited 30 male, untrained subjects (18–30 years) and randomized them into 1 of 3 groups: control (CON, n = 10), high-intensity resistance exercise (HI, n = 10), and high-volume resistance exercise (HV, n = 10). Subjects randomized to the resistance training groups were required to perform whole-body strength training exercises 3–5 days a week for 12 weeks. The exercise regimen consisted of 2–3 sets of 3–8 repetitions (80–90% of 1 repetition maximum [1RM]) for the HI group and 3–4 sets of 10–15 repetitions (50–70% of 1RM) for the HV group. Anthropometry, carotid artery diameters, peripheral and central blood pressure, and maximal dynamic strength were measured before and after the 12-week study period. Subjects were instructed to maintain their normal diet and avoid aerobic exercise during the study. After the intervention, both the HI and HV groups increased their maximal strength on the back squat, bench press, and seated row (all p < 0.05). However, there were no changes in arterial stiffness indices between the groups. Using a randomized controlled trial with validated measurements of arterial stiffness, chronic resistance training does not appear to influence central arterial stiffness, regardless of training volume and load.
Heat shock during in vitro maturation induces chromatin modifications in the bovine embryo
Authors: Camargo Luiz Sergio Almeida , Aguirre-Lavin Tiphaine , Adenot Pierre , Araujo Thamiris Dornelas , Mendes Vivian Rachel Araujo , Louro Iuri Drumond , Beaujean Nathalie , Souza Eliza Diniz
Published: August 2019

Heat stress compromises bovine oocyte developmental competence, but the effects of high temperature during oocyte maturation on embryo chromatin organization is unknown. In this study bovine oocytes were exposed to heat shock (41°C) for 12 h during in vitro maturation and then submitted to in vitro fertilization. The heat shock did not affect (P > 0.05) the cleavage but reduced (P < 0.01) the blastocyst rate on Day 7 and Day 8. No effect (P > 0.05) on total cell number was found, but the heat shock increased (P < 0.05) the proportion of apoptotic cells in blastocysts at Day 8. Immunofluorescence analysis of H3K9me3 and HP1 was performed in embryos at 52 h post in vitro fertilization. An accumulation of H3K9me3 in the nuclei of embryos derived from heat-shocked oocytes at four-cell and eight-cell stages was found. Also, a non-expected higher proportion (P < 0.05) of four-cell stage embryos displaying nuclei with increased HP1 fluorescence was observed, suggesting an abnormal chromatin compaction in embryos from heat-shocked oocytes. Embryos at eight-cell stage derived from heat-shocked oocytes displayed lower (P < 0.05) relative amount of HSP40 transcripts than control ones. In conclusion, heat shock before fertilization has an effect on embryo chromatin, influencing the accumulation of H3K9me3 and HP1 in early embryos as well as further development.
EXAMINATION OF THE WEED FLORA OF RUDER HABITATS AND THE POSSIBILITY OF SUPPRESSION WITH HERBICIDES
Authors: Vojinović Milić , Živić Jelica , Perić Sanja , Aksić Miroljub
Published: August 2019

Ruderal flora, as well as the vegetation that flora forms, represent an extremely dynamic floristic-vegetation complex and arean integral part of the most immediate living and working environment of human. It is formed and developed mainly in human settlements, as well as in the other anthropogenic environments that are occasionally or permanently under direct or indirect influence of various forms of human activity. Ruderal vegetation is found not only directly around the settlements, but also around all urban and accompanying facilities: along roads, paths and fences around houses, yards, walls and roofs, in avenues, on ruins, construction sites, landfills, along railway tracks, road and defense embankments, on wet and nitrified banks of rivers, near human settlements, in abandoned lawns, on the street walks with sandy areas, cemeteries, in degraded pastures, forests, etc. This essay presents the distribution and representation of economically harmful, invasive and quarantine weed species (Abutilon theophrasti, Agropyrumrepens, Amaranthusretroflexus, Calystegiasepium, Cirsiumarvense, Chenopodium album, Chenopodiumhybridum, Convolvulus arvensis, Cynodondactylon, Daturastramonium, Sonchusarvensis, Sorghum halepense, Xanthium strumarium…) at ten sites in the Nisava district. The assessment of species representation was done in two shootings (May and August) according to scale 1-4. The proper selection of herbicides depends, in a large extent, on the presence of dominant weed species and on the time of application.
Unboxing co-creation with students
Authors: Lystbæk Christian Tang , Harbo Karen , Hansen Christian Højbjerg
Published: August 2019

Co-creation has received increasing interest as a way of develop products and services in collaboration with customers and clients. Recently, co-creation has been introduced in higher education; however, there is no general agreement about what this entails, and while the concept of co-creation has been used in a number of differing contexts, descriptions tend to focus on potentials only and not the tensions inherent in this kind of collaboration.

In this paper we describe a conceptual model for co-creation with students and explore the potentials as well as the tensions inherent in co-creation with students at academic libraries. Through a case study at The Royal Danish Library, Aarhus University Library we develop a conceptual model for co-creation with students that identifies the key aspects of co-creation with students and indicates its key potentials and tensions.
NVivo courses in the library
Authors: Røddesnes Sara , Faber Hege Charlotte , Jensen Magnus Rom
Published: August 2019

In 2017, we started a project with the goal of offering a new service to academic staff and PhD candidates at the NTNU University Library: courses and guidance in the use of NVivo, a software to alleviate the workload in structuring and analysing qualitative research data.

Such software is useful for a plethora of subjects, like geography, anthropology, sociology, but also subjects like art history. Faculty members and PhD-candidates at NTNU have expressed enthusiasm when contacted about future courses in NVivo. Some employees have experience with NVivo, while others have tried to make their own tools and systems for analysis to fulfil their needs. Based on their feedback, experiences and valuable suggestions, we will offer the course in the fall 2018, either as a standalone library course or as a joint venture with one or more departments in the Humanities and Social Sciences faculties.

Our article will focus on how we have identified a new skillset and how we developed a new course for our patrons in close cooperation with them. In our article we will walk you through our ongoing project. We are very interested in feedback and hope to spark a discussion on the creation of new services in the libraries.
Multiple Saliency and Channel Sensitivity Network for Aggregated Convolutional Feature
Authors: Xiang Xuanlu , Wang Zhipeng , Zhao Zhicheng , Su Fei
Published: August 2019

In this paper, aiming at two key problems of instance-level image retrieval, i.e., the distinctiveness of image representation and the generalization ability of the model, we propose a novel deep architecture - Multiple Saliency and Channel Sensitivity Network(MSCNet). Specifically, to obtain distinctive global descriptors, an attention-based multiple saliency learning is first presented to highlight important details of the image, and then a simple but effective channel sensitivity module based on Gram matrix is designed to boost the channel discrimination and suppress redundant information. Additionally, in contrast to most existing feature aggregation methods, employing pre-trained deep networks, MSCNet can be trained in two modes: the first one is an unsupervised manner with an instance loss, and another is a supervised manner, which combines classification and ranking loss and only relies on very limited training data. Experimental results on several public benchmark datasets, i.e., Oxford buildings, Paris buildings and Holidays, indicate that the proposed MSCNet outperforms the state-of-the-art unsupervised and supervised methods.
Multilevel Language and Vision Integration for Text-to-Clip Retrieval
Authors: Xu Huijuan , He Kun , Plummer Bryan A. , Sigal Leonid , Sclaroff Stan , Saenko Kate
Published: August 2019

We address the problem of text-based activity retrieval in video. Given a sentence describing an activity, our task is to retrieve matching clips from an untrimmed video. To capture the inherent structures present in both text and video, we introduce a multilevel model that integrates vision and language features earlier and more tightly than prior work. First, we inject text features early on when generating clip proposals, to help eliminate unlikely clips and thus speed up processing and boost performance. Second, to learn a fine-grained similarity metric for retrieval, we use visual features to modulate the processing of query sentences at the word level in a recurrent neural network. A multi-task loss is also employed by adding query re-generation as an auxiliary task. Our approach significantly outperforms prior work on two challenging benchmarks: Charades-STA and ActivityNet Captions.
M2Det: A Single-Shot Object Detector Based on Multi-Level Feature Pyramid Network
Authors: Zhao Qijie , Sheng Tao , Wang Yongtao , Tang Zhi , Chen Ying , Cai Ling , Ling Haibin
Published: August 2019

Feature pyramids are widely exploited by both the state-of-the-art one-stage object detectors (e.g., DSSD, RetinaNet, RefineDet) and the two-stage object detectors (e.g., Mask RCNN, DetNet) to alleviate the problem arising from scale variation across object instances. Although these object detectors with feature pyramids achieve encouraging results, they have some limitations due to that they only simply construct the feature pyramid according to the inherent multiscale, pyramidal architecture of the backbones which are originally designed for object classification task. Newly, in this work, we present Multi-Level Feature Pyramid Network (MLFPN) to construct more effective feature pyramids for detecting objects of different scales. First, we fuse multi-level features (i.e. multiple layers) extracted by backbone as the base feature. Second, we feed the base feature into a block of alternating joint Thinned U-shape Modules and Feature Fusion Modules and exploit the decoder layers of each Ushape module as the features for detecting objects. Finally, we gather up the decoder layers with equivalent scales (sizes) to construct a feature pyramid for object detection, in which every feature map consists of the layers (features) from multiple levels. To evaluate the effectiveness of the proposed MLFPN, we design and train a powerful end-to-end one-stage object detector we call M2Det by integrating it into the architecture of SSD, and achieve better detection performance than state-of-the-art one-stage detectors. Specifically, on MSCOCO benchmark, M2Det achieves AP of 41.0 at speed of 11.8 FPS with single-scale inference strategy and AP of 44.2 with multi-scale inference strategy, which are the new stateof-the-art results among one-stage detectors. The code will be made available on https://github.com/qijiezhao/M2Det.
Learning Fully Dense Neural Networks for Image Semantic Segmentation
Authors: Zhen Mingmin , Wang Jinglu , Zhou Lei , Fang Tian , Quan Long
Published: August 2019

Semantic segmentation is pixel-wise classification which retains critical spatial information. The “feature map reuse” has been commonly adopted in CNN based approaches to take advantage of feature maps in the early layers for the later spatial reconstruction. Along this direction, we go a step further by proposing a fully dense neural network with an encoderdecoder structure that we abbreviate as FDNet. For each stage in the decoder module, feature maps of all the previous blocks are adaptively aggregated to feedforward as input. On the one hand, it reconstructs the spatial boundaries accurately. On the other hand, it learns more efficiently with the more efficient gradient backpropagation. In addition, we propose the boundary-aware loss function to focus more attention on the pixels near the boundary, which boosts the “hard examples” labeling. We have demonstrated the best performance of the FDNet on the two benchmark datasets: PASCAL VOC 2012, NYUDv2 over previous works when not considering training on other datasets.
Towards Optimal Fine Grained Retrieval via Decorrelated Centralized Loss with Normalize-Scale Layer
Authors: Zheng Xiawu , Ji Rongrong , Sun Xiaoshuai , Zhang Baochang , Wu Yongjian , Huang Feiyue
Published: August 2019

Recent advances on fine-grained image retrieval prefer learning convolutional neural network (CNN) with specific fullyconnect layer designed loss function for discriminative feature representation. Essentially, such loss should establish a robust metric to efficiently distinguish high-dimensional features within and outside fine-grained categories. To this end, the existing loss functions are defected in two aspects: (a) The feature relationship is encoded inside the training batch. Such a local scope leads to low accuracy. (b) The error is established by the mean square, which needs pairwise distance computation in training set and results in low efficiency. In this paper, we propose a novel metric learning scheme, termed Normalize-Scale Layer and Decorrelated Global Centralized Ranking Loss, which achieves extremely efficient and discriminative learning, i.e., 5× speedup over triplet loss and 12% recall boost on CARS196. Our method originates from the classic softmax loss, which has a global structure but does not directly optimize the distance metric as well as the inter/intra class distance. We tackle this issue through a hypersphere layer and a global centralized ranking loss with a pairwise decorrelated learning. In particular, we first propose a Normalize-Scale Layer to eliminate the gap between metric distance (for measuring distance in retrieval) and dot product (for dimension reduction in classification). Second, the relationship between features is encoded under a global centralized ranking loss, which targets at optimizing metric distance globally and accelerating learning procedure. Finally, the centers are further decorrelated by Gram-Schmidt process, leading to extreme efficiency (with 20 epochs in training procedure) and discriminability in feature learning. We have conducted quantitative evaluations on two fine-grained retrieval benchmark. The superior performance demonstrates the merits of the proposed approach over the state-of-the-arts.
La pteridoflora del Parque Nacional los Mármoles, Hidalgo, México
Authors: Ramírez Cruz Said , Sánchez González Arturo , Tejero Díez Daniel
Published: August 2019

El conocimiento sobre las especies de licopodios y helechos en el estado de Hidalgo es escaso, el objetivo principal de esta investigación fue contribuir al conocimiento de la riqueza y distribución de la pteridoflora en diferentes comunidades vegetales del parque nacional Los Mármoles (PNM), la segunda área natural protegida con mayor extensión territorial del estado de Hidalgo. El estudio se basó en la recolección exhaustiva de ejemplares en distintos tipos de vegetación. Se encontraron 11 familias, 28 géneros y 65 especies de helechos y una familia con seis especies de licopodios. Se citan siete nuevos registros para el estado de Hidalgo: Anemia mexicana var. makrinii, Argyrochosma palmeri, Cheilanthes spiculata, Pecluma alfredii var. cupreolepis, Polypodium puberulum, Selaginella sartorii y S. wrightii.
Delimitación de Neobuxbaumia mezcalaensis y N. multiareolata (Cactaceae) con base en análisis multivariados
Authors: Arroyo Cosultchi Gabriel , Terrazas Teresa , Arias Salvador , López Mata Lauro
Published: August 2019

Neobuxbaumia mezcalaensis y N. multiareolata son taxones pobremente definidos, donde la segunda especie fue descrita originalmente como variedad de la primera. Aunque varias propuestas de clasificación señalan que son especies independientes, existe aún controversia sobre su estatus taxonómico. Nuestra hipótesis de trabajo es que existen caracteres morfológicos que permiten la delimitación inequívoca de N. mezcalaensis y N. multiareolata . Para probarla, se realizaron análisis multivariados, con un total de 15 poblaciones, y como grupos para comparación también se analizaron representantes de especies relacionadas tales como N. squamulosa y de N. polylopha . Los resultados permiten reconocer que no existen fenotipos intermedios y que los individuos de las poblaciones analizadas se clasifican en sus respectivas especies. Se encontró que el tamaño y forma de la aréola, longitud de la espina central y patrón de distribución de las espinas radiales junto con otros cuatro caracteres referidos por autores previos, permiten diferenciar claramente a N. mezcalaensis de N. multiareolata . Con base en este cúmulo de evidencias proponemos que ambas especies pertenecen a taxones inequívocamente independientes.
UTK Laboratory Orientation/Training v1
Authors: Lecleir Gary , W Wilhelm Steven
Published: August 2019

Welcome to the Wilhelm Lab. This short training is to help orient those that are learning how to work in a laboratory environment as well as help those that are joining our lab to become acquainted with our procedures.
Reaction of the hemostatic system in response to hypercapnic hypoxia of maximum intensity ­depending on different types of preconditioning
Authors: Moskalenko S V , Shakhmatov I I , Kovalev I V , Shakhmatova K I , Vdovin V M
Published: August 2019

Aim. To study the adaptation reactions of the hemostasis system to hypercapnic hypoxia of maximum intensity in rats subjected to preliminary multiple exposure to ethylmethylhydroxypyridine succinate and hypercapnic hypoxia of submaximal intensity.

Methods. In the experiment, Wistar male rats (80 individuals) were used. Training cycles: 30-fold daily exposure to hypercapnic hypoxia of submaximal intensity (20 minutes — 9.0±0.5% O2, 7.0±0.5% CO2); administration of ethylmethylhydroxypyridine succinate (50 mg/kg) to animals for 30 days; combined effects of the two described modes. Tested experimental exposure was simulated as a single hypercapnic hypoxia of maximum intensity (20 minutes — 5.0±0.5% O2, 5.0±0.5% CO2) at the end of each of three 30-day training cycles.

Results. Preliminary 30-day exposure to both isolated hypercapnic hypoxia of submaximal intensity and combined exposure to ethylmethylhydroxypyridine succinate contributes to hypocoagulation shift in the hemostasis system and reduces the level of the markers of pre-thrombotic state in response to a single hypercapnic hypoxia of maximum intensity. The state of the hemostasis system after 30-day cycle of isolated use of an antihypoxant is characterized by the inhibition of the vascular-platelet system of the hemostasis system and preserved hypercoagulation shifts in its plasma unit. The obtained results suggest that both preliminary isolated effect of hypercapnic hypoxia of submaximal intensity and the combined effect of hypercapnic hypoxia and ethylmethylhydroxypyridine succinate increase the resistance of the hemostasis system in experimental animals to acute hypercapnic hypoxia of maximum intensity compared to rats of the control group. This was confirmed by the inhibition of the vascular-platelet system, hypocoagulation in the plasma unit, decrease in the level of thrombotic readiness markers and increase in the anticoagulant activity of the blood system compared to the control. At the same time, isolated course administration of ethylmethylhydroxypyridine succinate did not cause the same amount of adaptive changes to maximum intensity hypercapnic hypoxia, since only platelet suppression of the hemostasis and hypocoagulation via the internal coagulation pathway were registered.

Conclusion. Isolated exposure of hypercapnic hypoxia of submaximal intensity and its combined exposure with ethylmethylhydroxypyridine succinate increase the resistance of the hemostasis system to acute hypercapnic hypoxia of maximum intensity; isolated course administration of ethylmethylhydroxypyridine succinate does not cause the same amount of adaptive changes.
Clinical course and remission rate in adult patients with atopic asthma in Chelyabinsk
Authors: Ignatova G. L. , Zhorina Yu. V. , Abramovskikh O. S. , Zherebtsova I. A.
Published: August 2019

Data on asthma remission in adults are scarce worldwide and have not been searched in Russian Federation.

The aimof the study was to describe clinical course and remission rate in adult patients with atopic asthma in Chelyabinsk.

Methods. A retrospective analysis of 313 outpatient records of patients with atopic asthma aged 18 to 70 years was carried out. The patients were followed from 1992 to 2018. The median duration of the follow-up was 8 (5; 15) years. Then, the patients were surveyed by phone. Asthma Control Test (AСT) was used in 181 (58%) of 313 respondents. Clinical remission of asthma was determined as being symptom-free with no need in inhaled corticosteroids (ICSs) and short-acting β2-agonists (SABAs) during ≥ 1 year.

Results. The median age of asthma onset was 14.5 (8; 2) years in males and 28 (24; 36) years in females (p < 0.001). The diagnosis was made 5 years after the onset of symptoms. Asthma severity was related to gender: mild asthma was seen more often in males compared to females (p = 0.008). Allergic rhinitis and asthma comorbidity was found in 78% of patients. The proportion of patients sensitized to pollen was 72%; tree pollen allergens were the main cause of seasonal allergy (in 51% of patients). Different combinations of sensitization to indoor, animal, and pollen allergens (polysensitization) were detected in 80% of patients. Clinical remission of atopic bronchial asthma was determined in 22.7% of cases. Asthma remission was not related to the patient’s gender or age of symptom onset. The median age of the remission group patients was 33 (28; 39.5) years vs 40 (29; 51) years in patients without remission (p = 0.015). Asthma remission was associated with normal body mass index (23 (21; 24) kg / m2 vs 25 (22; 29) kg / m2 (p = 0.007); allergen elimination (p < 0.001) and allergen-specific immunotherapy (p < 0.001).

Conclusion. Predicting the probability of asthma remission and identifying conditions required to achieve the remission could improve our knowledge about asthma natural course and could increase treatment efficacy and adherence of patients to the treatment.
Guideline on medical care for patients with chronic obstructive pulmonary disease and other lung obstructive diseases during tobacco smoking withdrawal
Authors: Sakharova G. M. , Antonov N. S. , Mikhaylova Yu. V. , Peredel’skaya M. Yu.
Published: August 2019

Morbidity of chronic obstructive pulmonary disease (COPD) is consistently increasing last decades in Russian Federation. Similarly, the total morbidity is also increasing together with annual healthcare costs. The main risk factor of COPD is tobacco smoking. Therefore, the encouragement of smokers to quit smoking and medical care for nicotine withdrawal should be considered as main factors to control COPD morbidity. Bronchial hyperreactivity could occur early in smokers and COPD could develop in smokers with longer smoking history. Mild to moderate COPD is diagnosed in > 20% of smokers seeking medical aid for nicotine withdrawal. Typically, bronchial hyperreactivity becomes worse after quitting the smoking. This should be considered by a physician and long-acting bronchodilators should be used during nicotine withdrawal. Therefore, an individual plan is necessary for every smoking patient with COPD including quitting the smoking with consideration the severity of nicotine dependence and motivation to quit smoking. The individual plan should also include initiation or optimisation of bronchodilator therapy to prevent worsening of bronchial hyperreactivity. Quitting the smoking is the most effective intervention to slow COPD progression.
Fuentes documentales para el estudio de la prostitución en los siglos XVI y XVII en el Archivo y Biblioteca de Salamanca
Authors: Vivas Moreno Agustín , Arias González Luis
Published: August 2019

Se realiza a través de las fuentes documentales ubicadas en el archivo y biblioteca universitarios de Salamanca un análisis de la prostitución en los siglos XVI y XVII.
¿Qué historia enseñar?
Authors: Valdeón Baruque Julio
Published: August 2019

Se presentan a la consideración del lector las ponencias del ciclo "la historia hacia el tercer milenio" en el que participaron los profesores d. Josep Fontana, d. Julio Valdeón, d. José Luis Gómez Urdáñez y d.ª Isabel Burdiel.
The Oxidized proteins and activity of the Cl–/HCО3– exchanger in erythrocytes of patients with acute alcohol intoxication
Authors: Demidchik Lyudmila , Kolesnikova Yevgeniya , Muravlyova Larissa , Molotov- Luchanskiy Vilen , Kluyev Dmitriy , Bakirova Ryszhan , Omarova Indira , Ponamareva Olga , Tankibaeva Neila , Nukhuly Altynbek
Published: August 2019

Background: The purpose of this research was to study the morphological properties and the products of oxidative protein modification in erythrocytes of patients with acute alcohol intoxication. Two groups of subjects were analyzed. The first one included 39 patients with acute alcohol intoxication. The second group consisted of 14 healthy subjects. Methods: In erythrocytes the activity of Cl–/HCО3– exchanger, the reactive protein carbonyl derivatives and membrane-bound hemoglobin concentration were measured. Results: Our results demonstrated strong alteration of the Cl–/HCО3– exchanger activity in erythrocytes of patients with acute alcohol intoxication. A delay in the beginning of hemolysis during incubation of erythrocytes in the ammonium medium was observed. The concentration of protein carbonyls in erythrocytes of patients significantly increased in comparison to the control ones. A decrease in the membrane-bounded hemoglobin was observed as well. Conclusions: These findings indicate that ethanol toxicity is manifested by alteration of oxidized protein concentration and Cl–/HCО3– exchanger activity in erythrocytes. It is hypothesized that oxidized proteins are implicated in modulation of the erythrocyte cell volume regulation.
Bireylerin Tıbbi-Aromatik Bitki Tüketimini Etkileyen Faktörlerin Belirlenmesi: Erzurum Merkez İlçeleri Örneği
Authors: YÜZBAŞIOĞLU Rüveyda
Published: August 2019

Bu çalışmada, Erzurum
İli merkez ilçelerinde (Aziziye, Palandöken ve Yakutiye) kentsel alanda yaşayan
bireylerin tükettikleri tıbbi ve aromatik bitkileri bilinçli olarak mı
tüketildiği ya da ne amaçla tükettiklerini belirleyip ve tüketimi etkileyen
faktörlerin belirlenmesi amaçlanmıştır. Araştırma kapsamın görüşülen 384
bireyin ortalama yaşı 35,19, %63.80’ni erkek, %73,70’inin evli ve %58,85’nin
çocuğu olduğu belirlenmiştir. Araştırmada bireylerin tıbbi aromatik ürünleri
bilinçli tüketimini etkileyen faktörleri binary logit analizi yardımı ile
belirlenmeye amaçlanmıştır. Analiz sonuçları bireylerin cinsiyeti, çocuk sahibi
olma durumu, medeni durumu, hanedeki fert sayısı ve eşlerin çalışma durumu ile
tıbbi aromatik bitki tüketimindeki bilinçli olma durumu arasında anlamlı bir
ilişki ortaya konulmuştur. Araştırma sonucunda söz konusu bölgede bireylerin
tıbbi aromatik bitkileri tüketimi bilinç düzeyi çok düşük olmamakla beraber
tercih de kadınların ve yanlız yaşayanların daha çok tüketmeye meyilli olduğu
söylenebilir.
Karayolu Yük Taşımacılığında Kullanılan Standart Treyler Seçimine Etki Eden Faktörlerin Analitik Hiyerarşi Prosesi ve TOPSIS Yöntemleri ile Değerlendirilmesi
Authors: GÖRÇÜN Ömer Faruk
Published: August 2019

Taşımacılık
işletmelerinin ve operatörlerin farklı tür, marka ve özelliklere sahip
treylerler arasında en uygun ve en iyi treyleri seçebilmek için sarf ettikleri
çaba her geçen gün artmaktadır. Genel bir perspektifte değerlendirildiğinde,
standart treylerler seçimi çok sayıda faktörün etki ettiği son derece karmaşık
bir süreçtir. Treyler seçim sürecinde rasyonel sonuçların elde edilebilmesi
için karar verme probleminin çok kriterli karar alma metodolojilerinden
faydalanılarak çözülmesi gerekmektedir. Bu çalışmada Analitik Hiyerarşi Prosesi
(AHP) yöntemi ile TOPSIS yöntemleri seçilmiş, her iki yöntem entegre edilerek
hibrid bir model olarak uygulanmak yerine, ayrı ayrı uygulanarak, her iki yöntemle
gerçekleştirilen analiz sonucunda elde edilen çıktılar değerlendirilmiştir.
Ortaya çıkan sonuçların değişkenlik göstermesi durumunda bunun olası nedenleri
tartışılmıştır.
THE SEARCH FOR NEW MEASURES IN ORGANISATIONAL COMMUNICATION: A SYSTEMATIC LITERATURE REVIEW
Authors: Badjie Gibriel , Thoyib Armanu , Hadiwidjojo Djumilah , Rofiq Ainur
Published: August 2019

Purpose of the study: Communication is a central pillar in organisation, yet little genuine communication takes place in the organisation. The purpose of the paper is to craft communication model that promotes routine information availability and accessibility by simplifying the approach to organisational communication through the leadership level, functional level and operational level.
Methodology: The study applied systematic literature review (SLR) or systematic research synthesis (SRS) as the approach to gather data, analyse to address the research query. The study method embraces the definition of SLR by Rousseau et al. (2008). The conditions for literature search electronically was done through multiple journal sites. The gathered published material dated between 1961-2018.
Main Findings: The paper put forward three propositions to establish the argument for organisational communication. The findings show that there is no definitive agreement what constitute organisational communication as it is given many names like internal communication, employee communication, corporate communication etc. There is total lack of structural approach to organisational communication.
Applications of this study: The paper refocuses organisational communication towards a three-tier approach and challenges leadership to communicate in tandem with managerial roles as purported by Mintzberg in order to give prominence to organisational communication.
Novelty/Originality of this study: The paper introduces three new dimensions as measures of organisational communication with a new perspective on leadership communication, where Mintzberg’s managerial roles were used as reference for leadership communication responsibility which is missing in today’s organisation. The new measures of organisational communication are leadership level, functional and operational level.
VALIDAÇÃO DE INSTRUMENTO PARA AVALIAÇÃO DO CONHECIMENTO PROFISSIONAL ACERCA DA HIPODERMÓCLISE
Authors: Gomes Nathália Silva , Oliveira Thais Reis , Silva Andrea Mara Bernardes , Barichello Elizabeth
Published: August 2019

Objetivo: validar instrumento relativo ao conhecimento dos profissionais de saúde em hipodermóclise. Método: pesquisa metodológica conduzida por meio de validade de conteúdo e aparência. A validação foi realizada por um grupo de cinco expertises na temática. Posteriormente, procedeu-se com a aplicação do teste-piloto realizado com seis profissionais de saúde. Resultados: o instrumento demonstrou resultados satisfatórios no processo de validação de conteúdo e aparente, podendo ser confirmada para a utilização. Conclusão: o instrumento construído foi bem avaliado pelos expertises e os apontamentos levantados foram analisados com vistas à melhoria e aperfeiçoamento.
Strategies for Teaching Online RN-to-BSN Students the Health Impacts of Climate Change
Authors: Wasco Jennifer J.
Published: August 2019

The impact of climate change on human health is projected to worsen over the next century, threatening the world's population. Nurses need to be knowledgeable about the causes of climate change and its direct and indirect health consequences, to be able to provide appropriate care and to advocate for policy change. More now than ever, nursing faculty are charged with the responsibility to educate future health professionals about this important topic. This article provides an introduction to the impacts of climate change on nursing care delivery and shares the pedagogy of an introductory course developed for an online, postlicensure RN-BSN program based at a university with deep roots in environmental sustainability.
Mitigating a Nursing School's Impact on Climate Change: A Quality Improvement Project
Authors: Yang Bee , Demorest Shanda , Krzyzanowski Breanne
Published: August 2019

Background

Mitigation is one approach to addressing climate change, which focuses on reducing carbon dioxide and greenhouse gas emissions. Nurses play a critical role in mitigation to prevent the health impacts of climate change. Recommendations to mitigate climate change in higher education institutions reflect four themes: policy, people, process, and practice. This quality improvement project aimed to mitigate a metropolitan nursing school's impacts on climate change.

Methods

A Sustainability Champion Workgroup was formed to address gaps identified in the organizational needs assessment. A No Waste November (NWN) campaign and a Sustainability dashboard were created to engage participants and increase awareness about climate change and environmentally sustainable behaviors. A pre- and post-NWN survey, adapted from the Nurses ‘Environmental Awareness Tool, and waste disposal measurements over 6 weeks were used to assess the impact of these interventions.

Results

The post-NWN survey showed the greatest increases in mean scores for the following environmentally sustainable behaviors: biking, walking, carpooling, or taking public transportation to work; leading or participating in recycling initiatives; serving on committees that purchase sustainable supplies; and composting. Waste disposal measurements revealed a higher proportion of recycling to landfill waste during 5 out of the 6 weeks of measurement.

Conclusion

Nurses and higher education institutions play an important role in mitigating the human impacts on climate change through environmental sustainability initiatives. Barriers to adopting environmentally sustainable behaviors and incentives to support these behaviors also need to be examined and addressed in future projects.
Building Community Resilience to Mitigate Mental Health Effects of Climate Change
Authors: Connerton Charlotte S. , Wooton Angela K.
Published: August 2019

As global warming is taking effect, the number of natural disasters such as hurricanes, tornados, flooding, drought, and wildfires is increasing. The purpose of this article is to address the impacts of climate change on human health, using a model developed by the Centers for Disease Control and Prevention. The effects of natural disasters on mental health, and actions nurses can take to help build strong, resilient communities, are discussed in detail. Increasing awareness and building resilience will improve health outcomes. Strong social connections are a key component of community resilience. Strengthening the infrastructure of communities can mitigate the impact of climate changes.
DEVELOPMENT OF PERFORMANCE EVALUATION THEME: A SYSTEMATIC ANALYSIS OF THE LITERATURE
Authors: Matos Lucas dos Santos , Valmorbida Sandra Mara Iesbik , Martins Vinicius Abilio , Ensslin Sandra Rolim
Published: August 2019

This research aimed to identify the development of literature on performance evaluation. It is an exploratory and descriptive research study, with a quali-quantitative approach through bibliometric analysis, using the ProKnow-C intervention instrument. The analyses showed that the main featured article was by Neely, Gregory and Platts (1995). The most influential article in the portfolio was Bourne et al. (2000), with the highest level of betweenness.  The Balanced Scorecard is the tool that predominates in 23% of studies; in 30% of the works, was developed by proposing models based on the literature while in 24% of them it was based on a proposal developed by the authors. The study contributed to broaden the knowledge about the subject in order to allow an overview of the literature, when knowing the main authors working on the theme, periodicals, articles, themes, tools and areas of practice. Emerging views on the subject are also presented.
Sistem Informasi e-Voting Pemilihan Kepala Desa Berbasis SMS Gateway (Studi Kasus Desa Talang Seleman)
Authors: Assahur Muhammad , Fenando Fenando , Purwanto Timur Dali
Published: August 2019

Pemilihan kepala desa merupakan hal yang harus dilakukan karena berdasarkan peraturan perundang-undangan yang ada masa jabatan kepala desa ada batasnya sama halnya dengan presiden, kepala daerah dan jabatan lain. Tak menuntut kemungkinan di bidang pemilihan kepala desa juga menggunakan kemajuan teknologi informasi, seperti menerapkan pemungutan suara berbasis elektronik atau lebih dikenal dengan sebutan e-Voting. e-Voting telah berkembang di berbagai belahan dunia seperti belanda dan negara maju lainnya, e-Voting dapat berupa sebuah aplikasi desktop ataupun halaman web dan e-Voting dapat dilakukan dengan desktop biasa. Dalam perkembangan teknologi informasi sekarang ini e-Voting dapat dikembangkan melalui perangkat seluler seperti SMS Gateway ataupun aplikasi android pada telepon pintar. Dengan memanfaatkan metode SMS Gateway pemungutan suara pada pemilihan diharapkan dapat mempermudah dan mempercepat proses pemilihan tanpa harus berada dan antri di tempat pemungutan suara (TPS) dan juga dapat menghemat biaya operasional pemilihan dan menyediakan informasi akurat kepada pemilih mengenai hasil dari pemungutan suara.
Sıcak Pres ile Üretilmiş Al-Nano SiC Kompozitin Mekanik Özelliklerinin İncelenmesi
Authors: Yamanoğlu Rıdvan , Efendi Erdinç
Published: August 2019

Bu
çalışmada saf alüminyum (Al) matris içerisine ağırlıkça % 0.25, 0.5 ve 1
oranlarında nano silisyum karbür partikülleri ilave edilmiş ve ardından toz
karışımları önce mekanik alaşımlama, daha sonra sıcak pres ile sinterleme
işlemine tabi tutulmuştur. Sinterleme sonrasında elde edilen numuneler
metalografik işlemler ile hazırlanıp aşınma ve eğilme testlerine tabi
tutulmuştur. Aşınma testleri sonucunda, saf Al matrise artan miktarda
nanopartikül ilavesinin, belli orana kadar aşınma direncini arttırdığı
gözlenmiştir. Benzer şekilde, artan nanopartikül takviyesiyle, eğilme testi
sonuçlarında da gözle görülür artışın olduğu gözlenmiştir. Takviye
partiküllerinin yapı içerisindeki dağılımını incelemek amacıyla numunelere EDX
analizi ile elementel dağılım analizi yapılmıştır. Elde edilen sonuçlar
literatür ile karşılaştırılarak değerlendirilmiştir.