bluuebunny/crossref_metadata_2025 huggingface dataset:
Addressing as a manifestation of dialogicity in N. N. Evseev’s lyrical poetry
Authors: Gizhe Elena Dmitrievna , Zheltova Natalia Yurievna
Published: December 2023

The aim of the paper is to reveal the dialogical nature of addressing in the poems by the little-studied Cossack poet of the Russian émigré community N. N. Evseev (1891-1979). The paper analyzes the components of the paratext space of the writer’s lyrical poetry: titles, dedications, epistles and epigraphs. The main addressees of the most frequent dedications are identified: the Cossack poet N. N. Turoverov, the Soviet officer B. P. Popov, as well as Evseev’s son and mother. The author’s connections with the Tambov region are also analyzed. The scientific novelty of the research lies in shedding light on the dialogical nature of authorial addressing in Evseev’s lyrical poetry, its original cultural and historical context. The results have shown that dedications and epistles in Evseev’s creative work contribute to building a kind of dialogue between the past and the present, the emigrant and the Soviet, the native and the foreign, which is aimed at restoring the national and cultural integrity destroyed by the revolution. It has been found that the poet freely communicates with his addressees in his poems without restrictions in time and space, which also allows him to expand the range of his addressing, as well as to place the necessary semantic emphasis. Dialogism in Evseev’s authorial addressing also contributes to the expression of homesickness characteristic of all emigrants.
COVID-19 and Myasthenia Gravis Exacerbation in an Elderly Patient: a Case Report
Authors: Kaidashev I.P. , Lavrenko A.V. , Avramenko Ya.M. , Ozarchuk L.P.
Published: December 2023

Treatment of COVID-19 in elderly patients with myasthenia gravis (MG), an autoimmune disease characterized by increased dynamic muscle weakness, is associated with a number of challenges, such as chronic immunosuppression, exacerbation of MG, and polymorbidity.We present the case of an elderly patient with generalized seropositive MG who contracted COVID-19. Aggravating factors are the patient’s age, the duration of myasthenia gravis, COVID-19, and comorbidity (chronic coronary heart disease, diffuse cardiosclerosis, atrial fibrillation, NYHA class I heart failure, hyper­tension). The patient had a favorable outcome despite the exacerbation. The patient required intravenous injections of immunoglobulin (1 mg/kg) for 2 days, non-invasive ventilatory support, and treatment of respira­tory and urogenital nosocomial infections (Pseudomonas aeruginosa and Klebsiella oxytoca).COVID-19 led to exacerbation of MG, progression of muscle weakness, development of respiratory failure, and hypoxia in an elderly patient. Intravenous immunoglobulin is a possible effective medication in the treatment of this comorbid pathology.During the COVID-19 pandemic patients with MG may be at greater risk of worse outcomes than healthy individuals due to an immunodeficient state associated with immunotherapy and possible respiratory and bulbar muscle weakness. The examination of patients with MG and a COVID-19 may reveal new pathogenetic patterns and change the therapeutic strategy.Knowledge of the essence of the disease, the main links of its pathogenesis, the spectrum of modern therapeutic agents, and algorithms for their use allow us to improve the quality of medical care for patients with MG. The implementation of a comprehensive multidisciplinary approach in the treatment of these patients allows us to significantly reduce the mortality rate, prolong the life of patients, and improve its quality.
The Role of Cell-Mediated Immunity Deficiency in the Clinical Evolution of Patients with Tuberculosis Associated with HIV Infection
Authors: Lesnic E. , Todoriko L. , Semianiv I. , Ghinda S.
Published: December 2023

HIV infection induces severe immunosuppression, considered the major risk factor for tuberculosis (TB).
Objective — to evaluate the clinical characteristics of patients with TB-HIV co-infection based on the level of immune deficiency to establish recommendations for improving clinical case management.
Materials and methods. A prospective, selective study included 86 TB patients, divided into the study group with 38 cases of TB evolved into acquired immunodeficiency syndrome (AIDS), established with a CD4+ level ≤ 200/μL and the control group with 48 TB cases having CD4+ ≥ 200/μL.
Results and discussion. The study assessed the impact of the severity of the cell mediated immune deficiency associated with HIV infection on the clinical evolution of TB and the final therapeutic outcome. Laboratory indicators characterizing TB in AIDS included general leukocytosis, lymphocytopenia, eosino­philia, anemia and, in rare cases, thrombocytopenia. All AIDS patients were untreated with ARV, and only one-third were in the early stages of symptomatic HIV infection. Risk factors for TB in AIDS included rural residence, low education levels and mental disorders. Treatment success was low, and the death rate was high in both groups, emphasizing the impact of associated conditions. Despite differences in the serum level of CD4+ cells, the rate of therapeutic success was equally low in both groups, with one-third continuing antituberculosis treatment. The death rate was insignificantly higher in the TB on AIDS group (23.4 %) vs. 18.7 % in early HIV stages due to comorbidities associated with HIV infection.
Conclusions. The study identified risk factors for TB in patients diagnosed with AIDS stage of symptomatic HIV infection, including residence in rural areas, low education levels and mental and behavioral disorders associated with multiple causes such as alcohol consumption, drug use and toxoplasmosis of the central nervous system. Recommendations include complex screening for TB and HIV in all socially vulnerable groups, reinforced by primary prevention and an individualized therapeutic approach.
Benign and malignant (melanocytic and non-melanocytic) skin neoplasms: classification, clinical manifestations, diagnosis and treatment tactics (analysis of modern specialized literature and own clinical observations and diagnostic researches)
Authors: Hryshchenko R.V. , Bogomolets O.V. , Stepanenko V.I.
Published: December 2023

Objective — to analyze the currently existing classifications, possible causes, localization, clinical pattern and course of a number of benign and malignant skin neoplasms, as well as to determine the informative value of modern diagnostic methods (dermatoscopy, high-frequency ultrasound) in order to choose rational treatment tactics.

Materials and methods. Based on the analysis of the literature and the results of own clinical observations, dermatoscopic and high-frequency ultrasound diagnostic examinations, the clinical manifestations and morphological signs of a number of benign and malignant skin neoplasms are systematized.

Results and discussion. At the current stage, imaging methods of diagnosis occupy a leading place in the diagnosis of benign and malignant neoplasms of the skin. Relevant diagnostic methods include dermatoscopy and digital dermatoscopy with using artificial intelligence, high-frequency ultrasound, confocal microscopy and optical coherence tomography. Particular attention is paid to the diagnostic significance of high-frequency ultrasound, which allows non-invasive, real-time determination of the size and depth of invasion and assessment of the boundaries of benign and malignant skin tumors. The results of our own clinical observations and dermoscopic and high-frequency ultrasound examinations of a number of benign and malignant skin tumors are also presented, with a discussion of the received data.

Conclusions. Considering a rather large number of nosologies of benign and malignant skin tumors and their clinical variations, it is important to establish the correct diagnosis in a timely manner. Currently, imaging methods for diagnosing benign and malignant skin tumors, in particular, dermoscopy, high-frequency ultrasound, confocal microscopy and optical coherence tomography, are being actively introduced in dermatological practice. High-frequency ultrasound diagnostics of skin neoplasms is a sufficiently informative method that allows non-invasive, real-time determination of the size and depth of invasion, as well as the stage of proliferation of benign and malignant skin neoplasms. The combined use of dermatoscopy and high-frequency ultrasound diagnostics is important for the preliminary differentiation of benign and malignant skin neoplasms. This allows choosing a rational individual treatment tactic, as well as monitoring the effectiveness of the therapy.
FEATURES OF COMPACTIBILITY AND CONSOLIDATION OF WORKPIECES MADE OF MECHANOSYNTHESIZED DYSPROSIUM MOLYBDENUM POWDER
Authors:   Moscow Polytechnic University, SHARIPZYANOVA GUZEL , EREMEEVA ZHANNA ,   National University of Science and Technology MISiS
Published: December 2023

Dysprosium molybdate powder was prepared by the mechanochemical method from a stoichiometric mixture of molybdenum oxide and dysprosium oxide. The XRF, TEM and SEM methods showed that during mechanochemical treatment for 30 minutes, due to mechanochemical reactions between the initial powders, a fine powder of the Dy2MoO6 compound containing up to 8% Dy2(MoO4)3 was formed. The technological properties (fluidity, compactibility) of the mechanosynthesized dysprosium molybdenum powder, as well as its microstructure after sintering, have been investigated.
Quercetin/Anti-PD-1 Antibody Combination Therapy Regulates the Gut Microbiota, Impacts Macrophage Immunity and Reshapes the Hepatocellular Carcinoma Tumor Microenvironment
Authors: Wu Ruoxia , Xiong Jiaqing , Zhou Ting , Zhang Zhen , Huang Zhen , Tian Sha , Wang Yongli
Published: December 2023

Objective: The use of immune checkpoint inhibitors (ICIs) provides promising strategies for hepatocellular carcinoma (HCC) treatment. This study aimed to explore impact and underlying mechanism of the combination therapy of quercetin and anti-programmed cell death 1 (anti-PD-1) antibody on HCC. Methods: Orthotopically transplanted HCC tumors in mice were treated with quercetin, anti-PD-1 antibody, or a combination of both therapies. Histopathological changes and programmed cell death ligand 1 (PD-L1) expression were characterized by hematoxylin and eosin (H&E) and immunohistochemistry (IHC) staining. The diversity and differences of gut microbiota (GM) were evaluated through 16S rRNA sequencing. Levels of macrophage immunity-related cytokines were quantified by enzyme-linked immunosorbent assay (ELISA), quantitative real-time polymerase chain reaction (RT-qPCR), and Western blot. Results: Combination therapy reduced necrosis, fibrosis, and PD-L1 expression in liver tissues. Additionally, combination therapy reduced GM imbalance and increased abundance of Firmicutes, Actinobacteria, and Verrucomicrobiota at the phylum level as well as Dubosiella and Akkermansia at the genus level. Combination therapy improved macrophage immunity, raised the expressions of CD8a, CD4, CD11b, interleukin (IL)-10, and interferon (IFN)-γ , and declined the expressions of IL-4, IL-6, toll-like receptor 4 (TLR4), an inhibitor of nuclear factor κBα (IκBα), and the NFκB subunit p65. Upon combination therapy, expressions of M2 macrophage-related genes arginase-1 (Arg-1), IL-10, transforming growth factor-β (TGF-β), and matrix metalloproteinase-9 (MMP-9) were upregulated. Instead, M1 macrophage-related genes IL-6, IL-12a, IL-1β, and tumor necrosis factor-α (TNF-α) were downregulated. Conclusions: Quercetin/anti-PD-1 antibody combination therapy reshaped HCC tumor microenvironment in mice in parallel with regulating the GM and macrophage immunity.
Community Structure and Diversity of Rhizosphere Soil and Endophytic Bacteria during the Period of Growth of Moso Bamboo Shoots
Authors: Yuan Zongsheng , Liu Fang , Zeng Zhi-hao , Pan Hui
Published: December 2023

Background: The purpose of this study was to elucidate the community structure of rhizosphere soil bacteria and endophytic bacteria during the growth of moso bamboo (Phyllostachys edulis) shoots. Methods: This study collected the rhizospheric soil samples, tissue samples of rhizome roots, shoot buds, winter bamboo shoots, spring bamboo shoots, and samples of forest soil. Their metagenomic DNA was extracted, and the bacterial community structure and diversity characteristics were compared and analyzed using high-throughput sequencing technology. Results: These samples enabled the identification of 32 phyla, 52 classes, 121 orders, 251 families, and 593 genera of bacteria. The phyla primarily included Proteobacteria, Acidobacteria, and Cyanobacteria among others. Proteobacteria was the dominant phylum in the samples of bamboo shoots and rhizome roots, whereas Acidobacteria was dominant in the rhizosphere and forest soil samples. The predominant genera of the rhizome root samples were Acidothermus, Bradyrhizobium and Acidobacterium, and the predominant genera of the soil samples were Acidothermus and Acidobacterium. Conclusions: This study preliminarily revealed the regularity between the growth and development of bamboo shoots and the changes in the community structure of rhizosphere soil and endophytic bacteria, which provides insights into the relationship between growth and the bacterial community structure in different stages of bamboo shoots.
Lipid Peroxidation in Ferroptosis and Association with Nonalcoholic Fatty Liver Disease
Authors: Zhao Shengnan , Guo Yan , Yin Xunzhe
Published: December 2023

Nonalcoholic fatty liver disease (NAFLD) constitutes a commonly diagnosed liver pathology with perturbed lipid metabolism, which is mainly caused by excessive accumulation of fat in hepatocytes by various pathogenic factors. Currently, there are no effective drug treatments for NAFLD. Ferroptosis represents a novel form of programmed cell death depending on iron, which is driven by large cellular amounts of reactive oxygen species (ROS) and lipid peroxides. Ferroptosis plays critical regulatory roles in the pathogenesis of NAFLD, and overaccumulation of Fe2+ contributes to lipid peroxidation, which subsequently aggravates NAFLD. Therefore, ferroptosis suppression might constitute an important target for NAFLD treatment. This article reviews the discovery, production pathways, and defense mechanisms of ferroptosis, and explores its association with NAFLD. This may provide new reference targets and strategies for the development of NAFLD drugs from the perspective of ferroptosis.
Acute and training effects of dynamic resistance exercise on ambulatory blood pressure: A systematic review and meta-analysis
Authors: Braghieri Heloisa Amaral , da Silva Gustavo Oliveira , Farah Breno Quintella , Parmenter Belinda , Kanegusuku Hélcio , Dias Raphael Mendes Ritti , de Almeida Correia Marilia
Published: December 2023

Objective: This systematic review/meta-analysis aimed to verify the acute (24-hour) and training effects of resistance exercise on ambulatory blood pressure (ABP). Methods: PubMed, Web of Science, and Scielo databases were searched for crossover and/or controlled trials of resistance exercise in adults compared to a control group/condition, monitoring ABP. Mean differences (MDs) with 95% confidence intervals (95% CI) were calculated (p≤0.05 significant). Results: Twenty-four studies were included, 17 investigating acute (338 participants) and seven training effects (326 participants). Acutely we verified lower nighttime systolic BP in chronic disease (MD: -1.31; 95% CI: -2.27, -0.34; p=0.008), and lower daytime diastolic BP in healthy participants (MD: -0.77; 95% CI: -1.51, -0.03; p=0.040). Long-term effect revealed reductions in 24-hour systolic (MD: -4.00; 95% CI: -7.90, -0.09; p=0.050) and diastolic BP in chronic disease (MD: -1.34; 95% CI: -2.54, -0.14; p=0.03), and pooling groups (MD: -1.32; 95% CI: -2.29, -0.35; p=0.008). Meta-analysis revealed significant reductions in daytime systolic and diastolic BP in chronic disease (Systolic - MD: -5.63; 95% CI: -9.24, -2.03; p = 0.002; Diastolic - MD: -1.60; 95% CI: -2.77, -0.43; p=0.007) and pooling groups (Systolic - MD: -4.32; 95% CI: -7.09, -1.55; p=0.002; Diastolic - MD: -1.33; 95% CI: -2.31, -0.35; p=0.008). Conclusion: Resistance exercise acutely leads to lower nighttime systolic and daytime diastolic BP in healthy participants and chronic disease, while resistance training decreases 24-hour systolic and diastolic BP, daytime systolic and diastolic BP in chronic disease.
Do you want to stay single? Considerations on single arm trials in drug development and the post-regulatory space
Authors: Dyachkova Yulia , Dunger-Baldauf Cornelia , Barbier Nathalie , Devenport Jenny , Franzen Stefan , Kazeem Benga , Kuenzel Thomas , Mancini Pierre , Mordenti Giacoma , Richert Knut , Ridolfi Antonia , Saure Daniel
Published: December 2023

Single arm trials (SAT), while not preferred, remain in use throughout the drug development cycle. They may be accepted by regulators in particular contexts (eg., oncology and in rare diseases) when potential effects of new treatments are very large and placebo treatment is unethical. However, in the post-regulatory space, SATs are common, and perhaps even more poorly suited to address the questions of interest. In this manuscript, we review regulator and HTA positions on SATs, further challenges posed by SATs to address research questions beyond regulators, evolving statistical methods to provide context for SATs, case studies where SATs could and could not address questions or interest, and communication strategies to influence decision making and optimize study design to address evidence needs.
Will the ‘Anthropocene’ finally be formalized?
Authors: Rull Valentí
Published: December 2023

A proposal for the formalization of the ‘Anthropocene’ as a new geological epoch following the Holocene has just been submitted (31 October 2023) to the International Commission on Stratigraphy (ICS). This proposal, prepared by the Anthropocene Working Group (AWG) after 13 years of discussions, places the beginning of the ‘Anthropocene’ in the mid-20th century, and considers that the better-suited Global Stratotype Section and Point (GSSP) would be placed on the varved sediments of the Canadian Crawford Lake. The primary stratigraphic marker is considered to be the radioactive fallout resulting from the first nuclear weapon tests carried out in the 1940s and 1950s. These dates coincide with the Great Acceleration, characterized by an abrupt increase in the indicators of planetary anthropization. The AWG proposal is now being considered by the ICS Subcommission on Quaternary Stratigraphy (SQS), which can endorse or reject it, or ask for modifications. If endorsed, the proposal will be submitted to the ICS Executive for approval and, if approved, it will be sent to the International Union of Geological Sciences (IUGS) for ratification. The formalization of the AWG proposal is not guaranteed due to potential inconsistencies with the requirements of the International Stratigraphic Guide (ISG). Possible alternatives to an eventual rejection are briefly discussed.
Contributions of distractor dwelling, skipping, and revisiting to age differences in visual search (Preprint)
Authors: Wiegand Iris , van Pouderoijen Mariska , Oosterman Joukje , Deckers Kay , Horstmann Gernot
Published: December 2023

Visual search becomes slower with aging, particularly when targets are difficult to discriminate from distractors. Multiple distractor rejection processes may contribute independently to slower search times: dwelling, skipping and revisiting, measurable by eye-tracking. The present study investigated how age affects each of the distractor rejection processes, and how these contribute to the final search times in difficult (inefficient) visual search. In a sample of Dutch healthy adults (19-85 years), we measured reaction times and eye-movements during a target present/absent visual search task, with varying target-distractor similarity and visual set size. We found that older age was associated with longer dwelling and more revisiting of distractors, while skipping was unaffected by age. This suggests that increased processing time and reduced visuo-spatial memory for visited distractor locations contribute to age-related decline in visual search. Furthermore, independently of age, dwelling and revisiting contributed stronger to search times than skipping of distractors. In conclusion, under conditions of poor guidance, dwelling and revisiting have a major contribution to search times and age-related slowing in difficult visual search, while skipping is largely negligible.
Cardiac regulation, attachment style, and frustration tolerance in children with disruptive mood dysregulation disorder
Authors: Leal Michelle , Adan Marilyn , Heilman Keri J. , Cockcroft Kate
Published: December 2023

Disruptive mood dysregulation disorder (DMDD) is a childhood mood disorder characterized by severe difficulty in emotion regulation, particularly anger and irritability. Limited research has explored the relationship between attachment style and DMDD, despite the potential influence of attachment on physiological and behavioural regulation. This study investigated the role of attachment style, and subsequent adaptive shifts in parasympathetic regulation of the heart (indexed by vagal tone), as a potential contributing factor in the onset and maintenance of DMDD. The sample consisted of children who were diagnosed with DMDD (n=15) and a control group of typically developing peers (n =15). The avoidant attachment style was prominent in the DMDD group, compared to the control group. No differences in vagal tone were apparent at baseline or during a frustrating task. A negative correlation was found between the number of social interaction problems reported by parents in the DMDD group and autonomic regulation of the heart during the frustrating task. The study highlights the need for further research on the role of attachment style and physiological state regulation when frustrated to develop targeted interventions and support systems for children with DMDD.
Information Categorization for Canopy Mapping using Quality Control (QC) Tool – Affinity Diagram (KJ Method)
Authors: Nishant
Published: December 2023

Canopy mapping involves the process of accurately delineating and assessing the distribution and extent of green spaces, trees, and vegetation within a designated area. Understanding the canopy’s characteristics holds paramount importance, as it plays a critical role in supporting biodiversity, regulating microclimates, and mitigating the adverse impacts of urbanization on the environment. This research paper focuses on exploring the practical application of the KJ method and collaborative brainstorming to gather and organize relevant information for canopy mapping. The study engaged six undergraduate students, under the guidance of a faculty member specialized in geoinformatics, in a productive brainstorming session, generating twenty-one diverse ideas related to canopy mapping. Through a methodical process of iterative refinement and consensus-building, the students effectively grouped these ideas into four distinct categories: “Data Sources,” “Canopy Estimation Process,” “Canopy Map Development,” and “Accuracy Assessment.” The resulting Affinity Diagram served as a clear and well-structured representation of the research paper’s key aspects, harnessing the collective intelligence of the team to organize complex information and facilitate the precise mapping of tree canopies. This collaborative approach proved instrumental in enhancing the project’s efficiency and effectiveness, promoting a cooperative environment that fosters innovation and informed decision-making.
Role of Cooperative Planning in Mixed-Economy and Its Impact on Development in Nepal
Authors: Shahi Bhupendra Bahadur
Published: December 2023

This paper discusses the importance of cooperative planning in the country that followed the mixed economy. This paper is based on the qualitative approach and the data were collected through secondary sources. A developing country like Nepal may not be adequately sustainable without the development of both private and public welfare sectors. After 1950, more enterprises were introduced in Nepal to uplift the existing status of the cooperatives for development in a mixed economy; the effort could not able to give satisfactory results however, the path of gradual and steady economic recovery as market space in development found to be started for the pro-poor in Nepal. Cooperative planning has introduced the principle of three pillars (public, private, and cooperative) of development in a mixed economy to address the demand and interests of poor and marginalized people in society. For this purpose, co-operatives have been providing foundations for uplifting their livelihood through the process of capital formation, landing, and saving in Nepal. However, most of the cooperatives in Nepal have operated and are controlled by rich and elite sections of society. Consequently, the activities of cooperatives are not found to follow the pathway of the three pillars of the economy. Hence, there is still a gap between reality and rhetoric in the operation of cooperatives in Nepal that should be reduced to uplift the livelihood of the poor and marginalized people.
Eyelid Schwannoma. A Case Report
Authors: Sheikhghomi Sima , Shafaat Mahboubeh , Hasani Hamidreza
Published: December 2023

In this case report, we describe a 53-year-old woman who presented with a slow-growing lower lid mass in her right eye. On gross examination, a remarkable lower lid bulging was noted. On palpation, a subcutaneous oval-shaped mass with a firm consistency, measuring about 2cm, was noted. The uncorrected visual acuities of the patient were 20/20 (by Snellen chart) bilaterally, and the examinations of the anterior and posterior segments of both eyes were unremarkable. On the orbital Computed Tomography scan of the patient, a solitary and homogenous solid globular mass with the same density of the brain tissue was obvious. The patient underwent surgical excision. Microscopic assessment of the lesion revealed a biphasic hypercellular area (Antoni A) and myxoid hypocellular areas (Antoni B), containing slender cells with tapered ends, interspersed with collagen fibers, consistent with a diagnosis of schwannoma. In addition, some foci of nuclear palisading around the fibrillary process (Verocay bodies) could frequently be found throughout the highly cellular regions. Schwannomas rarely occur in the eyelids, but have clinical and paraclinical indicators which indicate the probable diagnosis. In conclusion, we suggest that eyelid schwannoma be considered as an element of the differential diagnoses list for subcutaneous lesions of the eyelid.
Comparison of Three Methods of Tonometry in Patients With Inactive Thyroid-Associated Orbitopathy
Authors: Karhanová Marta , Kalitová Jana , Malušková Miroslava , Schovánek Jan , Zapletalová Jana , Mlčák Petr , Marešová Klára
Published: December 2023

Introduction: Intraocular pressure (IOP) measurement in patients with thyroid-associated orbitopathy (TAO) can be difficult and misleading, particularly in patients with diplopia and eye deviation (esotropia or hypotropia). However, when measuring IOP, it is also necessary to pay sufficient attention to TAO patients without diplopia in primary gaze direction and without motility disorder that might not be readily apparent.

Purpose: The aim of this study was to evaluate the accuracy of measurement of intraocular pressure (IOP) using three different types of tonometers: the rebound tonometer (iCARE), the Goldmann applanation tonometer (GAT) and the non-contact airpuff tonometer (NCT) in patients with inactive TAO.

Materials and Methods: A total of 98 eyes of 49 adult patients with TAO were examined. The study group included 36 females and 13 males, with an age range of 19–70 years and a median age of 55.0. All the patients had evidence of thyroid disease, a history of mild to moderate TAO, no clinical signs or symptoms of active disease, and no diplopia in direct gaze direction. In addition to a comprehensive eye examination, all the patients underwent measurement of intraocular pressure with three tonometers: NCT, iCARE, and GAT. The measurements with these three devices were compared.

Results: The mean IOP was 18.1 ± 2.4 mmHg (range 13–25 mmHg) with GAT, 22.3 ±5.0 mmHg (range 13–35 mmHg) with NCT, and 18.0 ±2.4 mmHg (range 13.3–26 mmHg) with iCARE. The mean difference between the GAT and iCARE measurements (using the Bland-Altman analysis) was -0.1
±1.16 mmHg (limits of agreement -2.4 to 2.1). The mean difference between the GAT and NCT measurements was 4.2 ±3.6 mmHg (limits of agreement -2.8 to 11.2). The mean difference between the iCARE and NCT measurements was -4.3 ±3.7 mmHg (limits of agreement -11.6 to 2.9). No significant difference was found between GAT and iCARE (p = 1.000). However, there was a significant difference between GAT and NCT (p < 0.0001), as well as between iCARE and NCT (p < 0.0001).

Conclusions: In patients with TAO, NCT significantly overestimates IOP values compared to the GAT and ICare. By contrast, the iCARE rebound tonometer provides IOP measurements comparable to the gold standard GAT in these patients.
Anicinabe Aki—Invisible No More: Indigenous Urban History in the Abitibi Region
Authors: Radu Ioana , Wiscutie-Crépeau Nancy
Published: December 2023

This article explores the Indigenous historiography of the town of Senneterre and the Abitibi region in Quebec. As the centre of ancestral and contemporary social and spatial organization of three Indigenous nations—Anicinabe, Iiyiuu/Iinuu (Cree), and Atikamekw Nehirowisiw—the specificity of Senneterre allows for a more nuanced analysis that centres Indigenous epistemological traditions of kinship, responsibility, and care. We thus focus on the ways in which the Senneterre Native Friendship Centre (and, more broadly, the national and provincial friendship centre movement), through a politics of care, has consistently delinked from settler-colonial tenets to build and embody a vision of making home and weave a sense of belonging for the Indigenous families that have been excluded from the town’s imaginary. The authors show how the Friendship Centre and its members have contributed to the reexamination of analytical and conceptual underpinnings of Indigenous urbanization, from a process of acculturation, cultural and territorial dispossession, and assimilation to that of strengthening contemporary Indigenous identities and the flourishing of a civic society in a place where urban space cannot be disassociated from a complex and overlapping Indigenous sovereign presence.
Imagining the Settler-Colonial City: Introducing Urban Indigeneities and the Settler-Colonial City, a Special Issue of the Urban History Review
Authors: Veracini Lorenzo
Published: December 2023

This article introduces the essays collected in this special issue of the Urban History Review and sketches the urban imagination of settler-colonial political traditions. It focuses on the way settler cities are imagined, argues that the settler-colonial city may be seen as distinct from other urban formations, and suggests that the urban form is a constitutive component of settler-colonial formations and their imaginaries. Settlers, the founders of political orders in distant locales, have cities on their minds precisely because they are heading in the opposite direction. They focus on the city they will build and on the cities they are escaping. They are especially concerned with the ways in which the former is going to differ from the latter. This imagination should be considered when appraising the settler colonial city, an endeavour to which this special issue contributes.
Does the geographic distance affect the genetic differentiation among bilberry populations sampled in Bosnia and Herzegovina?
Authors: Hodzic Adnan , Kanlic Kenan , Lasic Lejla , Kalamujić Stroil Belma , Grahic Jasmin , Gasi Fuad , Konjic Almira
Published: December 2023

Isolation-by-distance (IBD) pattern among bilberry (Vaccinium myrtillus L.) populations has previously been reported for this species in northern Europe. However, the number of molecular studies conducted on bilberry, using everything from isoenzymes, RAPDs to microsatellite markers, are very few and far between. Considering that Bosnia and Herzegovina (B&H) is a country rich with diverse fruit genetic resources, conducting a genetic characterization of the naturally occurring V. myrtillus populations could yield valuable data for the conservation and utilization of this resource. This study entailed genotyping samples collected from three bilberry populations located in Fojnica, Kladanj, and Srebrenica municipalities using seven polymorphic microsatellite or SSR (simple sequence repeats) markers. The obtained molecular data was used to calculate the correlation between the physical distance of the individual B&H populations and a parameter of the genetic differentiation (pairwise Fst). The results of the correlation analyses revealed an absence of a significant isolation-by-distance pattern among the three examined B&H bilberry populations. In addition, the most pronounced genetic differentiation was detected between the Srebrenica and each of the two remaining B&H populations. At the same time, the values for pFst were significant, albeit much lower, between the Fojnica and Kladanj populations. Bilberries from the sampled Srebrenica population appear to be distinct from the other B&H populations, possibly due to the different genetic origin of this population.
Employee Ownership: What It Is & What It Can Achieve
Authors: Palmieri Michael , Cooper Chris
Published: December 2023

The idea of employee ownership is not new and has existed since at least the mid-19th century. Yet, it remains a lesser-known business model in the economy at large. There are many myths and misunderstandings around what employee ownership is, and what it can achieve. We address these misconceptions by reviewing a growing body of research that contrary to common assumptions demonstrates that employee ownership garners broad political support, individuals working at employee-owned companies experience a higher level of economic well-being, and firms who adopt its varied models have better performance outcomes. The goal of this chapter is to provide academics, economic development officials, and business owners a solid, evidence-based understanding from which to explore, and put into practice, employee ownership.
Страна ариев: пять тысячелетий между Каспием и Персидским заливом: монография, [электронное издание сетевого распространения] / А.А. Вартумян, П.Л. Карабущенко, Т.А. Шебзухова. – М.: «КДУ»; «Добросвет», 2023. – 306 с.
Authors: Вартумян А.А. , Карабущенко П.Л. , Шебзухова Т.А.
Published: December 2023

Настоящая монография представляет собой системное изложение историко-политических процессов, происходивших на территории Персии. Рассматриваются вопросы цивилизации-империи Ирана в процессе становления его государственности. В настоящем исследовании авторы прослеживают эволюцию политических элит Ирана в контексте развития его культуры и цивилизации. Как показывает элитология истории, именно политические элиты и их лидеры формируют и определяют тот уникальный набор кодов власти, которые складываются в традиции государственного бытия конкретной нации. Иранская нация создала свое уникальное государство-цивилизацию, которое подтвердило право на существование своей пятидесятивековой историей. Монография предназначена для студентов, аспирантов, преподавателей ВУЗов интересующихся историей международных отношений в региональной интерпретации.
PENGGUNAAN MEDIA SOSIAL DI KALANGAN ORANG TUA MILENIAL SEBAGAI MEDIA PARENTING
Authors: Fadlilah Sifa Nur , Vera Nawiroh
Published: December 2023

PENGGUNAAN MEDIA SOSIAL DI KALANGAN ORANG TUA MILENIAL SEBAGAI MEDIA PARENTINGTelah terjadi pergeseran yang manakala orang tua lebih sering memperoleh akses informasi tentang cara pola asuh dari media baru. Penelitian ini menggunakan metode kualitatif dengan pendekatan fenomenologi mikro di mana pembahasan dari hasil tersebut ialah tentang pemaknaan khalayak tentang parenting berdasarkan pengalaman masing-masing individu yang bertujuan untuk memperoleh informasi tentang cara orang tua mendidik anak di era digital saat ini. Akses informasi parenting awalnya hanya dapat di peroleh dari lingkungan sekitar (secara offline). Namun sekarang informasi tersebut dapat di akses secara daring (online) parenting dari media, yang pada awalnya seringkali memperoleh informasi tersebut dari orang tua, mertua, dan beberapa orang yang dituakan lainnya. Orang tua juga menerapkan parenting yang efektif jika orang tua mengetahui apa yang harus di buat untuk mendidik anak di era digital yang diantaranya: orang tua perlu mendampingi anak-anak sebagai generasi digital dan penggunaan media digital sesuai usia dan tahap perkembangan anak dan juga orang tua perlu mengetahui dan memahami dampak media digital pada kesehatan mata anak Kata Kunci: media sosial, instagram, aisah dahlan, parenting
Математичний аналіз ускладненого перебігу гострих хірургічних захворювань органів черевної порожнини
Authors: Voznyuk S. M. , Polovyy V. P. , Sydorchuk R. I. , Poljanica A. S.
Published: December 2023

У cтатті проаналізовано результати діагностики та лікування 130 хворих з гострими хірургічними захворюваннями органів черевної порожнини, ускладненими перитонітом. Запропонована методика оцінки тяжкості стану хворих з використанням коефіцієнта стану тяжкості (КСТ), розроблена шкала прогнозування ускладненого перебігу гострої хірургічної патології органів черевної порожнини і абдомінального сепсису, адаптована до умов роботи вітчизняних клінік. Використання КСТ і шкали прогнозування дозволило своєчасно виділити групу ризику хворих з можливим ускладненим перебігом, призначити адекватне лікування, зменшити кількість післяопераційних ускладнень на 5 %, релапаротомії – на 4,4 %, знизити післяопераційну летальність на 3,9 %.
Вплив клопідогрелю і аспігрелю на міокардіальну ішемію у хворих з нестабільною стенокардією
Authors: Zavalska T. V.
Published: December 2023

У сучасній кардіології приділяється велика увага дослідженню міокардіальної ішемії, особливо вивченню безбольової ішемії міокарда як проблеми раптової смерті. Антиангінальна терапія хворих з нестабільною стенокардією (передінфарктним станом), що включає комбінацію препаратів з антиагрегантним і антикоагулянтним механізмом дії, ефективна, бо зменшує не тільки загальну ішемію міокарда, а й питому вагу безбольової ішемії.
Методи діагностики, диференціальної діагностики та критерії прогнозу гіпоксично-ішемічного ураження головного мозку у недоношених новонароджених в гострому періоді
Authors: Znamenska T. K. , Kirilova L. G. , Shveykina V. B.
Published: December 2023

Стаття присвячена встановленню ранніх діагностичних, диференціально-діагностичних критеріїв та прогнозу гіпоксично-ішемічного ураження головного мозку (різного за характером й ступенем тяжкості) у недоношених новонароджених в гострому періоді на основі порівняльного аналізу результатів їх комплексного міждисциплінарного дослідження (анамнестичного, неврологічного, клінічного, інструментального – нейросонографічного, імуноферментного, зокрема динаміки змін рівня мозкового нейротрофічного фактора в сироватці крові).
Динамика функции внешнего дыхания и состояния сердечно-сосудистой системы у детей, больных бронхиальной астмой, на этапе длительного санаторно-курортного лечения
Authors: Tanaga V. A. , Kobets T. V.
Published: December 2023

Як показало дослідження, у дітей з бронхіальною астмою (БА) в період ремісії на етапі тривалої санаторно-курортної реабілітації (протягом року) у разі включення до комплексу реабілітаційних заходів дихального тренажера «PARI PEP 2» відмічалося достовірне збільшення ЖЄЛ, ФЖЄЛ, ОФВ1, ПОС, МОС25–МОС75 порівняно з дітьми, які отримували стандартний курс санаторного лікування. Крім того, покращилися показники PQ і QTc, що свідчить про зниження ризику розвитку аритмії, що загрожують життю. Це свідчить про доцільність включення тренажера «PARI PEP 2» до комплексу реабілітації у дітей з БА.
V конгрес серцево-судинних хірургів України і Польщі "Актуальні питання серцево-судинної хірургії", присвячений сторіччю від дня народження академіка М. М. Амосова
Authors: Knyshov G. V.
Published: December 2023

V конгрес серцево-судинних хірургів України і Польщі
Реформування державного управління України-Гетьманщини в 1734-1750 рр.
Authors: Лапшин Сергій , Конотопенко Олександр
Published: December 2023

In the conditions of formation of state-legal institutes of Ukraine, interest in the formation and development of the national state of the Ukrainian people in the XVII century is steadily growing. After all, it is an objective historical connection between the state-legal phenomena of Ukraine, which exist more than three centuries. Governing Council of the Hetman Office, both by name and by content, was a successful attempt by the Russian tsar to incorporate Ukraine into the Hetmanate. During the state reforms, the PSU implemented a number of measures planned by the Government of the Russian Empire which were aimed at establish control over central and local authorities, unification of Ukrainian case-law and legal proceedings in accordance with all-Russian models. In the course of being established as a temporary body that would worked before the election of a new hetman, the CCP, in its turn, initiated measures of an incorporation character. In particular, the PSG took over the powers of the Hetman and the administrative part of the General Military Office, the transformation of the HVC into a technical institution, the subordination of the General Chambers of Commerce, the regular reports of the HSC to the GPU and the Senat's, and the appointment of three Great Russian members to the General Military Tribunal. The activities of the CCU promoted the distribution of the clerical norms and traditions of the Russian Empire among the state bodies of the Hetmanate. This process was characterized by a purposeful policy of the imperial administration to engagement the Hetmanate's state bodies in the imperial state mechanism. The primary measures of the Russian government in the Hetmanate had changed in the financial sphere, in view of the inevitable war with Turkey. Thus, the functioning of the SSU was characterized by a complex of inkorporatsionnyh by nature, measures aimed at subordination of the Supreme state bodies of the Hetmanate to imperial power structures and the final inclusion of Ukraine into the Russian Empire.
Douleur et émergence de la conscience — Aspects éthiques
Authors: Calvino B.
Published: December 2023

L’analgésie intrathécale figure parmi les techniques interventionnelles de gestion de la douleur auxquelles il faut savoir penser précocement, elle est d’ailleurs largement recommandée. Ce mode d’infusion des analgésiques dans le liquide céphalorachidien permet une épargne en opioïdes et une meilleure efficacité antalgique. Malgré tout, son usage reste limité. Cet article est conçu pour rendre plus accessible l’utilisation de cette technique en déroulant le film de l’analgésie intrathécale. Le parcours du patient est détaillé en commençant par les freins, les indications, le rôle du pharmacien et de l’équipe technique, mais également les potentiels échecs.
Litigios climáticos basados en derechos humanos como manifestación de las articulaciones entre las escalas local, nacional y global
Authors: Hessling Herrera Franco David , Belmont Colombres María Eugenia
Published: December 2023

Reseña del libro de César Rodríguez Garavito (editor) (2022). Litigar la emergencia climática: la movilización ciudadana ante los tribunales para enfrentar la crisis ambiental y asegurar derechos básicos. Buenos Aires, Argentina: Siglo XXI, 457 pp.
The Structure of the National Economy of Russia: the Phenomenon of a Hy-brid
Authors: Martynov Arkady
Published: December 2023

In this compact article, the analysis is focused on the phenomenon of the heterogeneous structure of the modern national economy, which can rightfully be identified as hybrid. The relationship between the divergence of institutional orders and agency structures in Russian economy is considered. The objective reason for the approval of the state-capitalist structure, which dominates the hybrid national economic system, is substantiated.
Міжнародна тематика на сторінках українського журналу «Київська старовина» (1882–1906)
Authors: Ластовський Валерій Васильович
Published: December 2023

Мета дослідження полягає передовсім у аналізі публікацій журналу «Київська старовина» щодо оприлюднення міжнародної тематики на його сторінках на рубежі ХІХ–ХХ століть і можливості її використання у науковому та навчальному процесах вже у сучасних умовах. Це був перший український науковий журнал, в котрому підіймалися питання міжнародних відносин політичного, економічного та культурного характеру в історичному і тогочасному контексті. Авторами у цьому часописі виступали переважно українські дослідники, серед яких можемо назвати Ореста Левицького, Петра Орловського, Євгена Чикаленка, Володимира Щербину та ін. Публікації спиралися на виявлену дослідниками джерельну базу, котра на сьогодні є частково втраченою, а частково – важкодоступною. Основна увага в публікаціях журналу була зосереджена насамперед на подіях і процесах, що охоплювали територію Східної Європи і відбувалися у зв’язку з участю в них українських історичних діячів чи соціальних структур. Хронологічно інформація, оприлюднена в статтях, переважно зосереджується в рамках подій ХVІІ – початку ХХ століття. Територіально вона охоплює зв’язки українського суспільства із землями Австрії, Англії, Італії, Молдови, Німеччини, Османської імперії, Угорщини, Чехії, Франції, Швеції. Методологія дослідження базується на системному підході з використанням логічного та порівняльного методів. Завдяки цьому вдалося проаналізувати зміст публікацій, їх появу у відповідний історичний період та зв’язок із поточною суспільною ситуацією. Висновки дослідження вказують на системність публікацій у «Київській старовині» матеріалів із міжнародної тематики, їх різноманітність та можливість вивчення уявлень українських науковців кінця ХІХ – початку ХХ ст. щодо міжнародних відносин.
Боротьба з тероризмом в рамках нового міжнародного менеджменту
Authors: Мельник Михайло Іванович , Лікарчук Дарʼя Сергіївна
Published: December 2023

XX–ХХІ ст. ознаменувалися в історії людства безпрецедентною кількістю загиблих насильницьким шляхом – під час воєн, у збройних міжнаціональних, міжрелігійних конфліктах та в інших проявах насильства. Агресивність, мабуть, історично властива людині, і протягом останніх ста років вона набувала нових форм. Однією із «традиційних» форм прояву насильства (як фізичного, так і психологічного) є тероризм. Незважаючи на давню історію, в останні десятиліття тероризм ставав все більш обширним процесом і сьогодні несе загрозу вже не окремим людям або групам людей, а й державам та людському суспільству в цілому. Усе це ставить перед спеціалістами різного рівня, зокрема державними управлінцями, завдання проведення комплексного аналізу всього різноманіття причин, що породжують конфлікт терористів із суспільством, а також проблему вирішення (по можливості, мирним шляхом) ситуації, що склалася. Особливий інтерес у зв’язку з викладеним матеріалом представляє широкий аналіз проблеми, оскільки специфіка теми тероризму така, що в основному нею займаються представники спецслужб, державні службовці та управлінці, військові, юристи, криміналісти, історики, журналісти, психологи. І водночас дуже мало є робіт, в яких аналізується еволюція тероризму саме в Україні. Досі основний наголос науковці роблять на використання матеріалів зарубіжних дослідників, присвячених проблемам тероризму в нашій країні. Метою дослідження є виокремлення основних трактувань та функціоналу сучасного тероризму в рамках нового міжнародного менеджменту.