bluuebunny/crossref_metadata_2025 huggingface dataset:
Oxidative ornithine metabolism supports non-inflammatory C. difficile colonization
Authors: Pruss Kali M. , Enam Fatima , Battaglioli Eric , DeFeo Mary , Diaz Oscar R. , Higginbottom Steven K. , Fischer Curt R. , Hryckowian Andrew J. , Van Treuren William , Dodd Dylan , Kashyap Purna , Sonnenburg Justin L.
Published: January 2022

The enteric pathogen Clostridioides difficile (Cd) is responsible for a toxin-mediated infection that causes more than 200,000 recorded hospitalizations and 13,000 deaths in the United States every year1. However, Cd can colonize the gut in the absence of disease symptoms. Prevalence of asymptomatic colonization by toxigenic Cd in healthy populations is high; asymptomatic carriers are at increased risk of infection compared to noncolonized individuals and may be a reservoir for transmission of Cd infection2,3. Elucidating the molecular mechanisms by which Cd persists in the absence of disease is necessary for understanding pathogenesis and developing refined therapeutic strategies. Here, we show with gut microbiome metatranscriptomic analysis that mice recalcitrant to Cd infection and inflammation exhibit increased community-wide expression of arginine and ornithine metabolic pathways. To query Cd metabolism specifically, we leverage RNA sequencing in gnotobiotic mice infected with two wild-type strains (630 and R20291) and isogenic toxin-deficient mutants of these strains to differentiate inflammation-dependent versus -independent transcriptional states. A single operon encoding oxidative ornithine degradation is consistently upregulated across non-toxigenic Cd strains. Combining untargeted and targeted metabolomics with bacterial and host genetics, we demonstrate that both diet- and host-derived sources of ornithine provide a competitive advantage to Cd, suggesting a mechanism for Cd persistence within a non-inflammatory, healthy gut.
Circularity in animal production requires a change in the EAT-Lancet diet in Europe
Authors: van Selm Benjamin , Frehner Anita , de Boer Imke J. M. , van Hal Ollie , Hijbeek Renske , van Ittersum Martin K. , Talsma Elise F. , Lesschen Jan Peter , Hendriks Chantal M. J. , Herrero Mario , van Zanten Hannah H. E.
Published: January 2022

It is not known whether dietary guidelines proposing a limited intake of animal protein are compatible with the adoption of circular food systems. Using a resource-allocation model, we compared the effects of circularity on the supply of animal-source nutrients in Europe with the nutritional requirements of the EAT-Lancet reference diet. We found the two to be compatible in terms of total animal-source proteins but not specific animal-source foods; in particular, the EAT-Lancet guidelines recommend larger quantities of poultry meat over beef and pork, while a circular food system produces mainly milk, dairy-beef and pork. Compared with the EAT-Lancet reference diet, greenhouse gas emissions were reduced by up to 31% and arable land use reduced by up to 42%. Careful consideration of the feasible substitutability between animal-source foods is needed to define potential roles of animal products in circular human diets.
Responsibility of major emitters for country-level warming and extreme hot years
Authors: Beusch Lea , Nauels Alexander , Gudmundsson Lukas , Gütschow Johannes , Schleussner Carl-Friedrich , Seneviratne Sonia I.
Published: January 2022

The contributions of single greenhouse gas emitters to country-level climate change are generally not disentangled, despite their relevance for climate policy and litigation. Here, we quantify the contributions of the five largest emitters (China, US, EU-27, India, and Russia) to projected 2030 country-level warming and extreme hot years with respect to pre-industrial climate using an innovative suite of Earth System Model emulators. We find that under current pledges, their cumulated 1991–2030 emissions are expected to result in extreme hot years every second year by 2030 in twice as many countries (92%) as without their influence (46%). If all world nations shared the same fossil CO2 per capita emissions as projected for the US from 2016–2030, global warming in 2030 would be 0.4 °C higher than under actual current pledges, and 75% of all countries would exceed 2 °C of regional warming instead of 11%. Our results highlight the responsibility of individual emitters in driving regional climate change and provide additional angles for the climate policy discourse.
Tumor-targeted biomimetic nanoplatform precisely integrates photodynamic therapy and autophagy inhibition for collaborative treatment of oral cancer
Authors: Dai Hao , Yan Han , Dong Fan , Zhang Ludan , Du Ning , Sun Lisha , Li Ningyu , Yu Guohui , Yang Zeyuan , Wang Yuguang , Huang Mingwei
Published: January 2022

A biomimetic nanodelivery platform was camouflaged by oral cancer cell membranes through a simple method and realized the precise targeted treatment of tumors with PDT and an autophagy inhibition strategy.
Grignard reagent formation via C–F bond activation: a centenary perspective
Authors: Pietrasiak Ewa , Lee Eunsung
Published: January 2022

Grignard reagents formation by C–F bond activation was first reported 100 years ago and further examples followed.
Promoting charge separation by rational integration of a covalent organic framework on a BiVO4 photoanode
Authors: Gao Bin , Yu Xingyu , Wang Tao , Gong Hao , Fan Xiaoli , Xue Hairong , Jiang Cheng , Chang Kun , Huang Xianli , He Jianping
Published: January 2022

A covalent-organic framework is combined with BiVO4 by covalent bonding to obtain a high-performance heterojunction photoanode.
Synthesis, structures and properties of metal–organic frameworks prepared using a semi-rigid tricarboxylate linker
Authors: Rixson Daniel , Günay Sezer Güneş , Alp Emre , Mahon Mary F. , Burrows Andrew D.
Published: January 2022

A series of MOFs constructed from 5-((carboxymethyl)amino)isophthalic acid (H3cmai) have been prepared and characterised, with [Cd3(cmai)2(H2O)4]·4H2O demonstrating loss of water in a single-crystal-to-single-crystal transformation.
Polarization-dependent excitons and plasmon activity in nodal-line semimetal ZrSiS
Authors: Meléndez Juan J. , Cantarero A.
Published: January 2022

The optical properties of ZrSiS arise from intense excitonic activity, with different character and spatial extension depending on the polarization of the incident light. The system also exhibits plasmonic activity, while the plasmons are unstable and decay into electron–hole pairs.
Porous organic polymers for electrocatalysis
Authors: Yang Dong-Hui , Tao You , Ding Xuesong , Han Bao-Hang
Published: January 2022

The application of porous organic polymers in various electrocatalytic reactions has been systematically summarized.
Facet-dependent activity of shape-controlled TiO2 supported Au nanoparticles for the water–gas shift reaction
Authors: Tang Yuanting , Chen Yongjie , Liu Xiao , Wang ChengXiong , Zhao Yunkun , Chen Rong , Shan Bin
Published: January 2022

Temperature-dependent interfacial catalysis of Au/TiO2 catalysts for the water–gas shift (WGS) reaction.
Click-based conjugated microporous polymers as efficient heterogeneous photocatalysts for organic transformations
Authors: Gan Shaolin , Zeng Yan , Liu Jiaxin , Nie Junqi , Lu Cuifen , Ma Chao , Wang Feiyi , Yang Guichun
Published: January 2022

Click-based conjugated microporous polymers were found to be highly efficient photocatalysts for the Ugi reaction and α-oxidation of N-substituted tetrahydroisoquinolines.
Polar hydrogen species mediated nitroarenes selective reduction to anilines over an [FeMo]Sx catalyst
Authors: Li Siqi , Huang Zhipeng , Liu Huifang , Liu Meijiang , Zhang Chaofeng , Wang Feng
Published: January 2022

We herein present an efficient approach for the chemoselective synthesis of arylamines from nitroarenes and hydrazine over an iron-molybdenum sulfide catalyst ([FeMo]Sx).
The principle of detailed balancing, the iron-catalyzed disproportionation of hydrogen peroxide, and the Fenton reaction
Authors: Stanbury David M.
Published: January 2022

Over 200 publications report mechanisms that violate the principle of detailed balancing; a 10-step core mechanism is proposed that avoids these problems.
Hydroboration reactions using transition metal borane and borate complexes: an overview
Authors: Saha Koushik , Ghosh Sundargopal
Published: January 2022

Different types of hydroboration reactions driven by borane/borate complexes of transition metals are described.
Bubble-enhanced ultrasonic microfluidic chip for rapid DNA fragmentation
Authors: Sun Lin , Lehnert Thomas , Li Songjing , Gijs Martin A. M.
Published: January 2022

We present a new bubble-enhanced microfluidic approach for highly efficient DNA fragmentation, suitable for next generation sequencing platforms. Improved on-chip performance arises from acoustic streaming generated by oscillating bubble interfaces.
Polymer particles armored with cobalt oxide nanosheets for the catalytic degradation of bisphenol A
Authors: Escamilla Maria , Pachuta Kevin , Huang Kuan , Klingseisen Michael , Cao Huaixuan , Zhang Huichun , Sehirlioglu Alp , Pentzer Emily
Published: January 2022

2D particle surfactants are attractive for the formation of highly stable emulsions and use as templates to prepare composite structures with performance properties dependent on the composition.
Chemistry of magnetic covalent organic frameworks (MagCOFs): from synthesis to separation applications
Authors: Yadav Priya , Yadav Manavi , Gaur Rashmi , Gupta Radhika , Arora Gunjan , Srivastava Anju , Goswami Anandarup , Gawande Manoj B. , Sharma Rakesh K.
Published: January 2022

This review aims to explore the design, development and applications of magnetically supported covalent organic frameworks (MCOFs) in extraction of metal ions, nitro explosives and chemical pollutants.
One-step conversion of lignin-derived alkylphenols to light arenes by co-breaking of C–O and C–C bonds
Authors: Qiu Zegang , Wang Ying , Di Yali , Ren Xiaoxiong , Liu Weiwei , Li Zhiqin , Li Guangyu
Published: January 2022

The selectivity for light arenes, including benzene and toluene, in the conversion of 4-ethylphenol reaches 55.7% with 84.0% selectivity for arenes.
Cubic versus hexagonal – phase, size and morphology effects on the photoluminescence quantum yield of NaGdF4:Er3+/Yb3+ upconverting nanoparticles
Authors: Quintanilla Marta , Hemmer Eva , Marques-Hueso Jose , Rohani Shadi , Lucchini Giacomo , Wang Miao , Zamani Reza R. , Roddatis Vladimir , Speghini Adolfo , Richards Bryce S. , Vetrone Fiorenzo
Published: January 2022

The photoluminescence quantum yield (PLQY) of NaGdF4:Er3+/Yb3+ upconverting nanoparticles (UCNPs) as a function of size and shape is studied. Sub-20 nm α-phase UCNPs showed a higher PLQY compared to similar size β-phase UCNPs.
Synthesis of Co/CeO2 hetero-particles with abundant oxygen-vacancies supported by carbon aerogels for ORR and OER
Authors: Liu Zhenyuan , Wan Jinxin , Li Meng , Shi Zhaoping , Liu Junhua , Tang Yawen
Published: January 2022

We present a hybrid composed of CeO2 decorated Co nanoparticles supported on 3D porous carbon aerogels (Co-CeO2/C aerogels) with superior electrocatalytic performance towards the both ORR and OER by CeCl3/K3Co(CN)6-chitosan hydrogels derived method.
Gold nanocluster based nanocomposites for combinatorial antibacterial therapy for eradicating biofilm forming pathogens
Authors: Genji Srinivasulu Yuvasri , Mozhi Anbu , Goswami Nirmal , Yao Qiaofeng , Xie Jianping
Published: January 2022

Nanomaterial-based antimicrobial photodynamic therapy (aPDT) is evidenced as a promising approach for the eradication of drug-resistant bacterial biofilms.
Mechanically robust, creep-resistant, intrinsic antibacterial and reprocessable dynamic polyurethane networks based on azine moieties
Authors: Han Jinshi , Zhou Yawei , Bai Guanghang , Wei Wei , Liu Xiaoya , Li Xiaojie
Published: January 2022

The azine moieties provide outstanding creep-resistant, mechanical, exchangeable and intrinsic antibacterial properties.
Hierarchically porous MOF-based microneedles for glucose-responsive infected diabetic wound treatment
Authors: Yang Xiao-Xi , Chen Yan-Li , Feng Peng-Fei , Wang Cong-Cong , Li Xiang-Kai , Liu Liang-Liang , Tang Yu
Published: January 2022

In this work, hierarchically porous metal–organic framework (MOF)-based microneedles were designed for glucose-responsive infected diabetic wound treatment.
Co,N-co-doped graphene sheet as a sulfur host for high-performance lithium–sulfur batteries
Authors: Zhao Haili , Chen Peng , Fan Yu , Zhang Junkai , Jia HongSheng , Zhao Jianxun , Liu Heng , Guo Xin , Wang Xinwei , Liu Wanqiang
Published: January 2022

Design of two-dimensional graphene with dispersed Co–N catalysts as a multifunctional S holding material in Li–S batteries to improve the retention of LiPSs and accelerate the reaction kinetics.
A few upstream bifurcations drive the spatial distribution of red blood cells in model microfluidic networks
Authors: Merlo Adlan , Berg Maxime , Duru Paul , Risso Frédéric , Davit Yohan , Lorthois Sylvie
Published: January 2022

We show how Red Blood Cell (RBC) transverse migration downstream the first bifurcation of the network has an outsized impact on the RBC distribution at large scale, depending on the network architecture, as illustrated here for a square network.
A review of sodium chloride-based electrolytes and materials for electrochemical energy technology
Authors: Wei Wutao , Xu Jiaqiang , Chen Weihua , Mi Liwei , Zhang Jiujun
Published: January 2022

The progress of NaCl-based electrolyte and NaCl-based regulation strategy in electrochemical energy technologies are comprehensively reviewed, proposing the development of electrochemical energy technology based on the cost-effective NaCl.
Bioelastomers: current state of development
Authors: Magaña Ilse , López Ricardo , Enríquez-Medrano Francisco Javier , Kumar Sugam , Aguilar-Sanchez Andrea , Handa Rishab , Díaz de León Ramón , Valencia Luis
Published: January 2022

Bioelastomers are “sustainable” rubbery materials that are derived from renewable resources and/or are biodegradable. Herein, we analyse the most important types of bioelastomers, their current and upcoming applications, and synthetic pathways.
“All-in-one” hypergolic metal–organic frameworks with high energy density and short ignition delay
Authors: Li Zhi-Min , Xu Yi-Qiang , Wang Chao , Lei Guo-Rong , Zhang Rui , Zhang Lei , Chen Jian-Hua , Zhang Jian-Guo , Zhang Tong-Lai , Wang Qian-You
Published: January 2022

A type of all-in-one hypergolic MOF has been described, in which CTB ligands as triggers impart active sites for the ignition reaction and imidazole ligands with different substituent groups as bandgap mediators could optimize the hypergolicity.
3D hierarchical core–shell spiny globe shaped Co2P@Ni2P/NiCo2O4@CoO for asymmetric supercapacitors
Authors: Song Wen-Wei , Wang Bing , Li Chen-Ning , Wang Shi-Ming , Han Zheng-Bo
Published: January 2022

Core–shell spiny globe shaped Co2P@Ni2P/NiCo2O4@CoO–NF (CNNCC–NF) was constructed. The CNNCC–NF shows ultrahigh areal capacitance (10.11 F cm−2 at 2 mA cm−2). The CNNCC–NF//AC–NF device exhibits a high energy density and excellent stability.
A low-swelling and toughened adhesive hydrogel with anti-microbial and hemostatic capacities for wound healing
Authors: Zhang Liwei , Zhang Yajie , Ma Fanshu , Liu Xingzhu , Liu Yangzhong , Cao Yi , Pei Renjun
Published: January 2022

Hydrogel composed of Pluronic F127 diacrylate, quaternized chitosan diacrylate, silk fibroin, and tannic acid is able to maintain good tissue adhesion abilities for wound healing.
Ion channel-targeting near-infrared photothermal switch with synergistic effect for specific cancer therapy
Authors: Wang Shuangling , Lv Jie , Pang Yu , Hu Shuyang , Lin Yulong , Li Meng
Published: January 2022

An ion channel targeted nanoplatform which integrates chemotherapy, chemodymamic therapy and photoactivation of TRPV1 ion channels has been developed for specific cancer therapy.
Facilitating trehalose entry into hRBCs at 4 °C by alkylated ε-poly(l-lysine) for glycerol-free cryopreservation
Authors: Liu Xingwen , Gao Shuhui , Niu Qingjing , Zhu Kongying , Ren Lixia , Yuan Xiaoyan
Published: January 2022

High intracellular trehalose and cryosurvival of human red blood cells (hRBCs) were achieved at 4 °C via membrane perturbation of self-assembled nanoparticles of alkylated ε-polylysine with stabilization of poly(vinyl pyrrolidone).
Correction: Facile synthesis of near-infrared bodipy by donor engineering for in vivo tumor targeted dual-modal imaging
Authors: An Feifei , Xin Jingqi , Deng Caiting , Tan Xiaofang , Aras Omer , Chen Nandi , Zhang Xiaohong , Ting Richard
Published: January 2022

Correction for ‘Facile synthesis of near-infrared bodipy by donor engineering for in vivo tumor targeted dual-modal imaging’ by Feifei An et al., J. Mater. Chem. B, 2021, 9, 9308–9315, DOI: 10.1039/D1TB01883C.
Efficient singlet fission in nanoparticles of amphipathic anthracene–tetracene dyad with broadband light harvesting ability
Authors: Nie Xinyu , Liu Heyuan , Wang Weijie , Su Pengkun , Zhou Jun , Li Zhi , Liu Zhaobin , Tang Zhaofeng , Chen Yanli , Li Xiyou
Published: January 2022

An efficient SF material with broadband light harvesting ability was prepared by means of ultrafast intramolecular Förster resonance energy transfer.
The resolved jet of 3C 273 at 150 MHz
Authors: Harwood J. J. , Mooney S. , Morabito L. K. , Quinn J. , Sweijen F. , Groeneveld C. , Bonnassieux E. , Kappes A. , Moldon J.
Published: January 2022

Context.Since its discovery in 1963, 3C 273 has become one of the most widely studied quasars with investigations spanning the electromagnetic spectrum. While much has therefore been discovered about this historically notable source, its low-frequency emission is far less well understood. Observations in the megahertz (MHz) regime have traditionally lacked the resolution required to explore small-scale structures, such as knots and diffuse jet emission, that are crucial to understanding the processes that result in the observed emission. Advances in the processing of LOFAR international baseline data have now removed this limitation, providing the opportunity to explore this key area for the first time.

Aims.In this paper we use the first sub-arcsecond images of 3C 273 at MHz frequencies to investigate the morphology of the compact jet structures and the processes that result in the observed spectrum. We determine the jet’s kinetic power, place constraints on the bulk speed and inclination angle of the jets, and look for evidence of the elusive counterjet at 150 MHz.

Methods.Using the full complement of the LOFAR international stations (German, Poland, France, UK, Sweden), we produce 0.31 × 0.21 arcsec images of 3C 273 at 150 MHz. Using ancillary data at gigahertz frequencies, we fit free-free absorption (FFA) and synchrotron self-absorption (SSA) models to each region in order to determine their validity in explaining the observed spectra.

Results.The images presented display for the first time that robust high-fidelity imaging of low-declination complex sources is now possible with the LOFAR international baselines. We show that the main small-scale structures of 3C 273 match those seen at higher frequencies, with a tenuous detection of an extension to the outer lobe. We find that FFA and SSA models are able to describe the spectrum of the knots and, while differentiating between model types requires further observations, we conclude that absorption is present in the observed emission. We determine the kinetic power of the jet to be in the range of 3.5 × 1043–1.5 × 1044erg s−1, which agrees with estimates made using higher frequency observations. We derive lower limits for the bulk speed and Lorentz factor ofβ≳ 0.55 and Γ ≥ 1.2, respectively. The counterjet remains undetected at 150 MHz, placing a limit on the peak brightness ofScj_150< 40 mJy beam−1.
The width of Herschel filaments varies with distance
Authors: Panopoulou G. V. , Clark S. E. , Hacar A. , Heitsch F. , Kainulainen J. , Ntormousi E. , Seifried D. , Smith R. J.
Published: January 2022

Context. Filamentary structures in nearby molecular clouds have been found to exhibit a characteristic width of 0.1 pc, as observed in dust emission. Understanding the origin of this universal width has become a topic of central importance in the study of molecular cloud structure and the early stages of star formation.

Aims. We investigate how the recovered widths of filaments depend on the distance from the observer by using previously published results from the Herschel Gould Belt Survey.

Methods. We obtained updated estimates on the distances to nearby molecular clouds observed with Herschel by using recent results based on 3D dust extinction mapping and Gaia. We examined the widths of filaments from individual clouds separately, as opposed to treating them as a single population. We used these per-cloud filament widths to search for signs of variation amongst the clouds of the previously published study.

Results. We find a significant dependence of the mean per-cloud filament width with distance. The distribution of mean filament widths for nearby clouds is incompatible with that of farther away clouds. The mean per-cloud widths scale with distance approximately as 4−5 times the beam size. We examine the effects of resolution by performing a convergence study of a filament profile in the Herschel image of the Taurus Molecular Cloud. We find that resolution can severely affect the shapes of radial profiles over the observed range of distances.

Conclusions. We conclude that the data are inconsistent with 0.1 pc being the universal characteristic width of filaments.
Total reflection of a flare-driven quasi-periodic extreme ultraviolet wave train at a coronal hole boundary
Authors: Zhou Xinping , Shen Yuandeng , Tang Zehao , Zhou Chengrui , Duan Yadan , Tan Song
Published: January 2022

Context. A flare-driven quasi-periodic extreme ultraviolet wave train totally reflected at a coronal hole boundary was well imaged on both temporal and spatial scales by AIA/SDO.

Aims. We aim to investigate the driving mechanisms of the quasi-periodic wave train and demonstrate the total reflection effect at the coronal hole boundary.

Methods. The speeds of the incident and reflected wave trains are studied. The periodic correlation of the wave trains with the related flare is probed. We compare the measured incidence angle and the estimated critical angle.

Results. We find that the periods of the incident and reflected wave trains are both about 100 s. The excitation of the quasi-periodic wave train was possibly due to the intermittent energy release in the associated flare since its period is similar to that of the quasi-periodic pulsations in the associated flare. Our observational results show that the reflection of the wave train at the boundary of the coronal hole was a total reflection because the measured incidence and critical angles satisfy the theory of total reflection: the incidence angle is smaller than the critical angle.
A uniform bound on costs of controlling semilinear heat equations on a sequence of increasing domains and its application
Authors: Wang Lijuan , Zhang Can
Published: January 2022

In this paper, we first prove a uniform upper bound on costs of null controls for semilinear heat equations with globally Lipschitz nonlinearity on a sequence of increasing domains, where the controls are acted on an equidistributed set that spreads out in the whole Euclidean space ℝN. As an application, we then show the exact null-controllability for this semilinear heat equation in ℝN. The main novelty here is that the upper bound on costs of null controls for such kind of equations in large but bounded domains can be made uniformly with respect to the sizes of domains under consideration. The latter is crucial when one uses a suitable approximation argument to derive the global null-controllability for the semilinear heat equation in ℝN. This allows us to overcome the well-known problem of the lack of compactness embedding arising in the study of null-controllability for nonlinear PDEs in generally unbounded domains.
Aspects regarding the explosion risk assessment of installations in atmospheres with combustible dust
Authors: Popa Cătălin Mihai , Păun Florin Adrian , Gabor Dan Sorin
Published: January 2022

Many industrial processes involving the presence of dust and combustible dust, suspended or accumulated in the form of deposits, have the potential to lead to a fire, explosion or decomposition in the presence of oxygen. As the damage caused by an explosion of dust is generally greater than that caused by explosions of flammable gases and vapours, a special attention must be paid to measures and means of protection and prevention of explosions of dust.

A dust explosion can only occur if there is mainly a potentially explosive atmosphere generated by the air / dust mixture and a source of ignition.

The level of safety is given by the operational efficiency of the employees and technical equipment involved in the production process to ensure that at least one of the above conditions is eliminated. The probability of a dust explosion is related to the physicochemical properties of the processed materials, together with the nature of the operations performed and the equipment used.

This paper highlights the principles and factors that must be taken into account when conducting an explosion risk assessment in installations with combustible dust atmospheres in order to establish prevention and protection measures, with the aim of ensuring a tolerable level of risk.
A new perspective on musculoskeletal disorders – emerging ergonomic risks in the European Union and Romania
Authors: Boatca Maria - Elena , Coroian Alexandra , Draghici Anca
Published: January 2022

According to the European Agency for Health and Safety at Work, changes in employment arrangements, new technologies and an increasing ageing population are key sources of emerging risks. New and emerging risks should be a major area of interest for every organisation, as a thorough risk prevention activity is key to high organisation efficiency and increased employee wellbeing. Musculoskeletal disorders (MSDs) are not a new risk category by themselves, but the changing characteristics of the work system generate new types of MSDs as a profession-related pathology (work-related MSDs). There is limited literature on this matter, hence the paper provides relevant insights and a new perspective on ergonomic risks and MSDs. Also, the paper presents a comparative analysis of ergonomic risks in the EU and Romania – based on secondary data – and identifies emerging risks in this category.
Investigating the relationship between job satisfaction, communication style, employee behavior in conflict situations
Authors: Caldarescu Gabriela , Florea Laura , Lohan Nicoleta Monica , Bernevig Mihai-Adrian
Published: January 2022

This study was designed to test the relationship between job satisfactions, communication style and conflict behaviour of employees in the public system, respectively in the territorial labour inspectorates. Research responds to practical needs highlighted by organizational psychology to identify the sources and dimensions that prevail and make the individual's perception of the organization lead to increased job satisfaction. However, the paper is not without methodological limits, represented by the use of self-report evaluation questionnaires that could involve poor identification and reporting, by the tendency of the facade that appears when the subject is not honest, offers answers that do not reflect its true feelings, principles and values, tends to avoid the appropriate responses to the state, only to leave a good impression, determine a positive judgment, placement in a situation of appreciation, or out of a desire to help the researcher in confirming the study hypothesis. The paper provides additional information for the scientific community, and can also be a starting point for other research by methodologically improving and bringing to the fore variables that can have a significant contribution to job satisfaction in civil servants, the subject being of maximum interest in the current context when a qualitative increase of services for employees and employers is desired.
Technical – organizational measures for classifying pyrotechnic articles
Authors: Cioara Cristian Raul , Morar Marius Simion , Băbuț Andrada Denisa
Published: January 2022

Pyrotechnic articles shall be classified by manufacturers according to their type of use, their purpose and their level of risk, including their noise level, and the notified bodies shall confirm the classification as part of the conformity assessment procedures. In accordance with the relevant national legislation, the national authority must take all appropriate measures to ensure that pyrotechnic articles do not endanger the health and safety of persons. If the national market surveillance authority has sufficient reasons to consider that a pyrotechnic article poses a risk to the health, safety of persons or other aspects of the protection of the public interest, it shall carry out an assessment of the pyrotechnic article concerned. INCD INSEMEX Petrosani is an accredited institution, to carry out such technical expertise according to the legislation in force harmonized with the European regulations, having also adequate modern facilities for fulfilling the requirements of the standards in the field. The paper also highlights the results of the modernization of the methodological and practical infrastructure as well as the technical facilities that underlie the substantiation of the new approach in terms of optimizing and increasing the quality of the process.
Application of flammability testing methods for conveyor belts intended for use in potentially explosive atmospheres in order to select suitable types for field application
Authors: Păun Florin Adrian , Gabor Dan
Published: January 2022

The conveyor belts are widely used and can be found, for example, in the underground and surface mining industry as well as in other industries involving the transport of various products, materials, etc.

The need to ensure the transport of various products, materials, involves the use of conveyor belts in normal environments as well as in environments with a potentially explosive atmosphere.

When used in potentially explosive atmospheres, conveyor belts shall not be sources of ignition for the explosive atmospheres generated by gases, vapors, flammable mists and/or combustible dusts in the mixture with the air.

This involves the use of conveyor belts in a particular construction, compliance with the applicable essential safety and health requirements as well as granting a special attention to the identification/selection of types suitable for the specific field application.

The purpose of the paper is to highlight the importance of testing by accredited laboratory tests, the flammability properties of conveyor belts intended for use in potentially explosive atmospheres, in order to easily identify/select, by end users, the types of conveyor belts adequate for specific application.
Computer simulations in the ventilation network of the Vulcan Mine
Authors: Boantă Corneliu , Tomescu Cristian
Published: January 2022

Maintaining safety and health conditions underground, especially where potentially explosive atmospheres are possible, depends mainly on how the ventilation system is built, applied and operated in the ventilation network. The ventilation networks of a mining unit for the exploitation of the useful mineral substance are mining works that aim to ensure optimal microclimate conditions in the underground. An ventilation network is built of nodes and branches, in order to establish its structure. In order to establish the optimal air flows at branch level, specialized programs are used, with the help of which the modeling, solving and optimization of the ventilation networks can be performed. Optimizing the management of the ventilation system involves in-depth and complex analyzes on the ventilation network that require a huge volume of data that can be processed only with the help of computing technology. The paper presents an analysis of the ventilation network of the Vulcan mine using the calculation technique to simulate situations that may occur in the ventilation system.
Implications of coal disappearance from the energy mix in Romania
Authors: Apostu Izabela-Maria , Lazar Maria , Faur Florin
Published: January 2022

The firm commitment of the European Union (EU) to fully implement the 2030 Agenda requires the Member States to find and implement solutions to meet global targets, including ensuring clean and affordable energy. The EU encourages the elimination of coal from the energy mix in order to quantitatively reduce emissions and the impact on the environment and human health. Romania attaches great importance to the 2030 Agenda and understands that developing the national economy, increasing the quality of life, and caring for the environment are inextricably linked to the development and modernization of the energy system, for which the National Energy Strategy 2019-2030 was developed. According to it, in the perspective of 2050, Romania will be based on a diversified, balanced, and modern energy mix through clean technologies. But what if coal would disappear from the energy mix? The causes of the disappearance of coal from the energy mix could be represented by global or national policies or the depletion of known exploitable reserves, the latter being a less probable variant. In this paper, we aim to highlight and analyze some scenarios related to the possibilities of replacing coal in the energy mix, which would change the perspectives.
Public transport analysis in the Petroșani Basin in the context of the need for sustainable mobility
Authors: Mihăilescu Sorin , Praporgescu Gabriel
Published: January 2022

Sustainable public transport requires finding a balance between economic and social objectives, ensuring the need for mobility without damaging environmental and health factors. At the level of the Petroșani Basin, the aim is to ensure the mobility of passengers as quickly as possible from one city to another (from east to west - Petrila, Petroșani, Aninoasa, Vulcan, Lupeni, Uricani) or from one part of the city to another, as the case may be. The study of population fluctuations by hours, on working or non-working days, per season allows the realization of a public transport that ensures the movement of people as quickly and safely as possible. The purpose of this paper is to study the way in which public transport is carried out in the Petroșani Basin, the means of transport used and the possibilities to improve this activity. In the context of sustainable mobility, the paper includes necessary aspects (transport demand, influencing factors, infrastructure) in order to conclude on the future of public transport in the Petroșani Basin.
Theoretical and experimental analysis on environmental pollution with exhaust gases at the mechanical dislocation of rocks, located in a protected nature environment
Authors: Nan Marin Silviu , Vitan Daniel Cosmin , Anotoiu Sorina Daniela , Aron Cristian
Published: January 2022

The paper approaches the theoretical and experimental analysis of the level of exhaust gas pollution in a protected nature environmental, located in the mountain area, for excavation a trench. Due to the legislative provisions prohibiting the use of explosives in the nature reservation or other protected nature environmental areas, the mechanized excavation solution remains the only viable option. Excavation the trench through the mechanized solution must be carried out, taking into account the maximum level of pollution with exhaust gases provided in the legislative norms. According to the geotechnical data, the rock composition to be excavated on the route will be of different hardness, which involves impactors of various powers to displace the rock, on the one hand, and on the other, different excavators and bulldozers for the handling the material resulted from excavation. The theoretical research required to solve the problem has several stages, of which we mention: choosing the correct mechanization solution for displacing the hard and very hard rock; determination of fuel consumption, and energy consumption, respectively, transformation of the energy consumed in the liquid fuel necessary for the tool driving engines, and which generate exhaust gases.
A literature review on Building Integrated Solar Energy Systems (BI-SES) for façades − photovoltaic, thermal and hybrid systems
Authors: Bot Karol , Aelenei Laura , da Glória Gomes Maria , Silva Carlos Santos
Published: January 2022

The building façade has a crucial role in acting as the interface between the environment and the indoor ambient, and from an engineering and architecture perspective, in the last years, there has been a growing focus on the strategic development of building façades. In this sense, this work aims to present a literature review for the Building Integrated Solar Energy Systems (BI-SES) for façades, subdivided into three categories: thermal, photovoltaic and hybrid (both thermal and photovoltaic). The methodology used corresponds to a systematic review method. A sample of 75 works was reviewed (16 works on thermal BI-SES, 37 works on photovoltaic BI-SES, 22 works on hybrid BI-SES). This article summarises the works and later classifies them according to the type of study (numerical or experimental), simulation tool, parametric analysis and performance when applied.
Computational modeling of battery thermal energy management system using phase change materials
Authors: Narasimha Raju Pusapati Laxmi , Manas Chalumuru , Rajan Harish
Published: January 2022

Similar to an IC (Internal combustion) engine which requires cooling to operate at optimum temperature for better efficiency; electric vehicles do require a similar system. There are various methods used in the current market for thermal management of batteries, of these our paper focuses on phase change materials (PCM). This cooling strategy can store an enormous amount of heat produced inside a battery because of its high latent heat capability. A 3D model of the battery using the multi-scale multi-dimension model (MSMD) for battery simulation and Solidification/melting models were used to showcase the melting of PCM due to the heat generated from a cell. ANSYS fluent was used to carry out the simulations. These computations are carried out at different C-rate to find the time taken for a battery to discharge and to find the impact of C-rate on PCM performance. Besides, temperature data for the cell was recorded before and after PCM was involved to compare the temperature difference between various PCM's.
Advanced Reliability Analysis of Mechatronic Packagings coupling ANSYS©and R
Authors: Hamdani Hamid , Radi Bouchaïb , El Hami Abdelkhalak
Published: January 2022

The complexity challenges of mechatronic systems justify the need of numerical simulation to efficiently assess their reliability. In the case of solder joints in electronic packages, finite element methods (FEM) are commonly used to evaluate their fatigue response under thermal loading. Nevertheless, Experience shows that the prediction quality is always affected by the variability of the design variables. This paper aims to benefit from the statistical power of the R software and the efficiency of the finite element software ANSYS©, to develop a probabilistic approach to predicting the solder joint reliability in Mechatronic Packaging taking into account the uncertainties in material properties. The coupling of the two software proved an effective evaluation of the reliability of the T-CSP using the proposed method.
Literature review of bridge structure's optimization and it's development over time
Authors: Zaheer Qasim , Yonggang Tan , Qamar Furqan
Published: January 2022

The structural development in bridge engineering along with efficiency have got much attention in few decades. Leading to the development, Optimization of structure established on mathematical analysis emerged mostly employed strategies for productive and sustainable design in the bridge engineering. Despite the widespread knowledge, there has yet to be a rigorous examination of recent structural optimization exploration development. Thus, the primary objectives of this paper are to critically review previous structural optimization research, provide a detailed examination of optimization goals and outline recent research field limitations and provide guidelines for future research proposal in the field of bridge engineering structural optimization. This article begins by outlining the relevance of efficiency and sustainability in the bridge construction, as well as the work done required for this review. Suitable papers are gathered and followed by a statistical analysis of the selected publications. Following that, the selected papers are evaluated in terms of the optimization targets as well as their spatial patterns. Structure's optimization four key steps, including modeling, optimization techniques, formulation of optimization concerns and computational tools, are also researched and examined in depth. Finally, research gaps in contemporary works are identified, as well as suggested guidance for future works.
Communication in Healthcare: Global challenges in the 21st Century
Authors: Etheredge Harriet Rosanne , Fabian June
Published: January 2022

This article explores the communication challenges brought about by the digital revolution in the 21st century for healthcare professionals internationally. It particularly focuses on the use of content-generating and sharing platforms like social media. Globally, healthcare has been irrevocably altered by digital innovation and health professionals deploy an extensive range of social media and web-based tools on a daily basis. However, many healthcare professionals use these platforms in a regulatory vacuum—where there may not be specific legal or ethical guidance—and without an appreciation of the associated risks. Given the special protections afforded to the practitioner–patient relationship, and the importance of a health practitioners' reputation, it is vital that we understand how to traverse the many ethical and legal challenges of the digital interaction. A comprehensive set of recommendations (see “Guidelines for Good Digital Citizenship in the Health Professions” on page 5 ff.) to keep practitioners out of trouble is provided. These hinge on the notion of being a “good person and a good doctor” as a formative maxim for ethical and legal safety. The constituents of publication, and the consequences of falling foul of acceptable publication standards on social media, are specifically discussed. “Publication” involves sharing content with a third party, or a group of people, and social media refers to platforms on which content can be shared with more than one person. Hence, most information that we post on social media can be considered as “published,” and as such may attach liability for health professionals who do not use these platforms with requisite care and sufficient forethought.
Paraganglioma of the Cauda Equina – Case Report and Literature Review
Authors: Salame Arthur Araújo Massoud , Pereira Bernardo de Andrada , Camara Lygia Sampaio de Arruda , Araújo Iogo Henrique de Oliveira , Pinheiro Filipe Moreira de Almeida , Carvalho Estevão Cardoso , Neves Francisco Weldes Brito das , Pinheiro José Alvaro Bastos
Published: January 2022

Paragangliomas of the cauda equina are tumors of rare incidence, with ~ 220 cases described in the world literature. They are benign lesions, grade I by the World Health Organization (WHO), whose definitive diagnosis can only be made by immunohistochemical analysis. Its neuroendocrine nature is evidenced by the presence of chromogranin. The relevance of reporting this case is because paragangliomas of the cauda equina should be included among the differential diagnoses of intradural and extramedullary tumors, and especially because they can cause perioperative and intraoperative hypertensive crises by adrenergic discharge.

The present study presents the case of a 36-year-old male patient diagnosed with a lumbar spine tumor located in the central spinal canal that presented as cauda equina syndrome involving 4 months of bilateral sciatica, paraparesis, urinary and fecal retention. The diagnosis of paraganglioma was confirmed by immunohistochemical positivity for chromogranin after microsurgical resection of the tumor.
Effectiveness of Structured Counseling and Preventive Strategies in Promoting Awareness and Expressed Habitual Practices Toward Prevention of Urinary Tract Infection Among Women of Reproductive Age Group: A Pilot Study
Authors: Sequera Sonia Karen Liz , Chacko Leena Kunnath
Published: January 2022

Objectives Urinary tract infection (UTI) is the most common infection that affects half of all women in their lifetime and one-fourth have recurrent infections. Health behaviors could prevent the recurrence of UTIs and therefore motivation and increasing awareness are necessary for healthy behavior change. This study was done to evaluate the effectiveness of structured counseling and preventive strategies (SCAPS) in promoting awareness and expressed habitual practices among the women of the reproductive age group to prevent UTI.

Materials and Methods Block randomization with multiple interventions and follow-up were conducted among 60 women (30 in each group, randomly assigned using the SNOSE technique) attending the OBG and urology OPDs of a selected medical college hospital. Purposive sampling was used to select the subjects. Women who were positive for urine culture and experiencing typical symptoms of UTI, as assessed using the symptom score checklist, were recruited for the study. Pre-test awareness was assessed using a structured awareness questionnaire and a rating scale for expressed habitual practice. After the pre-test, on the same day, the experimental group received SCAPS intervention followed by a second session during the third month. At the third (before the second session) and the sixth-month post-tests were conducted by delivering the same tool to determine the post-test level of awareness and expressed habitual practice after the administration of SCAPS.

Results The study shows there is a significant difference in the awareness and expressed habitual practice values in the experimental group (p < 0.005). The effectiveness of SCAPS showed that the mean ± standard deviation (SD) pre-test score of women (awareness - x̄1 ± SD = 9.47 ± 2.57, hygienic habitual practice - x̄1 ± SD = 20.93 ± 1.91, fluid and dietary practice - x̄1 ± SD = 7.73 ± 2.18 and sexual habits - x̄1 ± SD= 8.00 ± 3.33) was significantly lower than the mean ± SD post-test scores (awareness - x̄2 ± SD =11.37 ± 1.65, awareness - x̄3 ± SD = 12.00 ± 1.05), (hygienic habitual practice - x̄2 ± SD = 22.57 ± 2.16, x̄3 ± SD = 23.90 ± 1.99), (fluid and dietary practice - x̄2 ± SD = 10.07 ± 2.21, x̄3 ± SD =11.97 ± 1.79) and (sexual habits - x̄2 ± SD = 8.81 ± 2.51, x̄3 ± SD =9.81 ± 2.26).

Conclusion SCAPS was found to be effective on awareness and preventive habitual practices with regard to UTI. SCAPS can be recommended for vulnerable groups such as females so that UTI could be prevented.

Trial Registration CTRI/2018/10/016064 (Registration on 17/10/2018).
SWI/SNF-Related SMARCA2 Gene Mutation Associated with Nicolaides–Baraitser's Syndrome: Follow-up Study
Authors: Akella Radharamadevi
Published: January 2022

Nicolaides–Baraitser's syndrome is a rare, dominantly inherited well-delineated syndrome caused by mutations in the SMARCA2 gene which is located on the small arm of chromosome 9. In this study, a de novo missense variant, which was identified in a 3-year-old boy by whole exome sequencing is reported. The de novo heterozygous V1198M missense variant in SMARCA2 gene in exon 25 is novel. Identifying the condition is crucial for the long-term management and family counseling. Follow-up over 4 years revealed improvements in overall performance.