bluuebunny/crossref_metadata_2025 huggingface dataset:
Endocytosis-like vesicle fission by membrane-expanding molecular machine enabling virus encapsulation for in vivo delivery
Authors: Uchida Noriyuki , Ryu Yunosuke , Takagi Yuichiro , Suzuki Kotono , Higuchi Yuji , Hoshino Norihisa , Akutagawa Tomoyuki , Matsubara Teruhiko , Sato Toshinori , Anraku Yasutaka , Shimokawa Naofumi , Ito Hiroaki , Takagi Masahiro , Morita Masamune , Ajioka Itsuki , Muraoka Takahiro
Published: September 2022

Since the cellular process of endocytosis enables uptake of biomacromolecules interacting with the cell surface by outside-in vesicle fission, endocytosis-like membrane deformation is an ideal methodology for the incorporation of micrometer-size biomacromolecules into vesicles. However, such endocytosis-like vesicle fission, which requires expansion of the liposomal membrane, has never been realized using artificial liposomal systems. Here, we developed a membrane-expanding molecular machine containing a diazocine core (AzoMEx), which exhibits an opening/closing mechanical motion in response to visible light. Upon blue light irradiation, AzoMEx embedded in a 1,2-dioleoyl-sn-glycero-3-phosphocholine bilayer expanded the liposomal membrane, assembled, and eventually induced outside-in endocytosis-like fission. When this vesicle fission was induced in the presence of micrometer-size M13 phage, it was efficiently incorporated into the vesicle by interacting with AzoMEx. The encapsulated M13 phage was transiently protected from the external environment, retaining its biological activity, and thus could be distributed throughout the body after blood administration.
Endometrial receptivity during hormonal therapy in women of reproductive age with abnormal uterine bleeding due to ovulatory disorders
Authors: Ten Angelica R. , Oboskalova Tatyana A. , Vorontsova Anna V.
Published: September 2022

Background. After an episode of abnormal uterine bleeding, it is of critical importance to restore endometrial receptivity to prevent the recurrence of abnormal uterine bleeding and implement reproductive plans.
Aim. To study endometrial steroid receptor expression in women of reproductive age after an episode of abnormal uterine bleeding due to ovulatory dysfunction during micronized progesterone or combined oral contraceptive therapy with bioidentical estrogen and dienogest.
Materials and methods. A cohort prospective study was conducted. The study included 70 females aged 1840 years who were observed with abnormal uterine bleeding due to ovulatory dysfunction at the Department of Obstetrics and Gynecology of Ural State Medical University based at the Yekaterinburg Municipal Hospital №40 from 2016 to 2018. After a bleeding episode, the patients received a combined oral contraceptive with bioidentical estrogen and dienogest or micronized progesterone.
Results. During therapy, variable changes in the expression of estrogen and progesterone receptors in the stromal and glandular components of the endometrium during the 6-month follow-up were observed.
Discussion. Changes in steroid receptor expression and endometrial receptivity during hormone therapy are similar, although certain trends are identified which can guide the choice of hormone therapy.
Conclusion. Due to the lack of complete recovery of steroid receptor expression and endometrial receptivity, even 6 months after hormonal treatment, short courses of hormonal rehabilitation after abnormal uterine bleeding due to ovulatory dysfunction are not sufficient, and permanent hormonal contraception or periodic courses of progestogens are required to prevent a relapse of the endometrial proliferation.
Association of VEGF cytokine levels and single nucleotide polymorphisms of the VEGF-A gene with the genital endometriosis in the female population of the Northwestern Federal District of Russia
Authors: Kulikova Natalia V. , Litvinova Larisa S. , Shperling Natalia V. , Ivanov Andrei V.
Published: September 2022

Aim. To study the association of neoangiogenesis VEGF-A gene polymorphisms C(-460)T (rs833061), C(+936)T (rs3025039) with the risk of genital endometriosis in the population of the Northwestern Federal District; to examine the relationship of polymorphic variants of the VEGF-A neoangiogenesis gene C(-460)T (rs833061), C(+936)T (rs3025039) with the concentration of VEGF-A factor in the blood of females with genital endometriosis.
Materials and methods. Eighty-five female volunteers aged from 19 to 44 (mean age 32.9 (5.8) years) with a histologically confirmed diagnosis of genital endometriosis were included in the stud; also, 79 females without endometriosis according to diagnostic laparoscopy for infertility or ectopic pregnancy, aged 20 to 42 (mean age 32.5 (7.2) years, p=0.71) were included in the study. The obtained data were analyzed using SPSS 20.0 statistical software package; 2 value and p value were estimated.
Results. In our study, we found an association between the C allele and the CC genotype of the C(+936)T (rs3025039) polymorphism of the VEGF-A gene with genital endometriosis: odds ratio (OR) 2.35, 95% confidence interval (CI) 1.034.61, p=0.023; OR 1.89, 95% CI 1.034.61, p=0.048, respectively. The TT genotype of the C(-460)T (rs833061) polymorphisms and the TT genotype and the C(+936)T (rs3025039) allele of the VEGF-A gene were less common in patients with genital endometriosis: OR 0.43, 95% CI 0.141.29, p=0.023; OR 0.06, 95% CI 0.043.18, p=0.001; OR 0.43, 95% CI 0.231.29, p=0.023 respectively. The blood concentration of VEGF-A cytokine was lower in patients with genital endometriosis at all genotypes of C(-460)T (rs833061) locus of VEGF-A gene than that in females without endometriosis. The analysis of genotype frequency distribution of polymorphic site C(+936)T of the VEGF-A gene showed that the VEGF-A cytokine level was 1.5 times higher in the comparison group with heterozygous ST genotype versus that in homozygous genotypes. Enzyme immunoassay in the examined females showed a 2.5-fold decrease in the level of the VEGF-A angiogenic cytokine in blood serum in patients with endometriosis compared to those without endometriosis.
Conclusion. To better understand the pathogenetic features of the endometriosis course and to make an individual prognosis of the course and therapy efficacy, an additional analysis of the associations between the polymorphisms of the listed genes and the angiogenesis factor level is required.
Prospects of exogenous inositols in maintaining of skin, hair and nails condition: A review
Authors: Gromova Olga A. , Torshin Ivan Yu. , Tetruashvili Nana K.
Published: September 2022

Myoinositol (MI) and D-chiroinositol (DCI), used in the therapy of menstrual disorders, polycystic ovarian syndrome (PCOS), hirsutism, acne, gestational diabetes, and other diseases, are required for intracellular signal transduction from insulin and other hormone receptors. Clinical practice shows that, for instance, MI and DCI in the treatment of PCOS improve the condition of skin, hair, and nails. These effects of MI and DCI are related to the normalization of insulin signaling and support of differentiation and growth of various skin cell types (keratinocytes, fibroblasts, epitheliocytes, etc.). The effects of MI and DCI on the skin and its appendages, including in wound healing, can be enhanced by manganese, which provides an antioxidant effect and improves the connective tissue matrix of the skin, and folic acid, which is involved in amino acid metabolism, proliferation, and differentiation of dividing cells.
Morphosyntactic Structures of Existential, Possessive and Locative Constructions in Amharic
Authors:   Addis Ababa University, Ethiopia, A. Getahun
Published: September 2022

This paper lays out the morphosyntactic structures of existential, locative and possessive constructions in Amharic. Amharic belongs to South Ethio-Semitic language subfamily. It is natively spoken in the Amhara region and used as the first and the second language for some urban dwellers in the country. It is a working language for the Federal Government of Ethiopia. It serves the same in Gambella, Southern Nations, Nationalities and Peoples’ and Benishangul-Gumuz regional states. The Amharic existential, possessive and locative constructions are characterized by using the same existential verb stem all-‘exist’. The verb is defective in its derivation and conjugation. Unlike the prototypical verbs of the language, the existential verb uses a different verb for imperfective and past verb forms. Unlike the regular verbs of the language, the existential verb, which is perfective in form, conveys present tense. It has been observed that indefinite nominals appear as the E (Existent) in existentials and possessives, whereas definite ones appear in locatives. The morphosyntactic features of existentials and locatives are the same in every aspect except the use of definiteness of the E (Existent). The possessives differ from the two constructions in word order and morphological structure of the verb.
EkeGusii Morphopragmatics and the Junction with Iconicity
Authors:   Kisii University, Kenya, E.O. Mariera
Published: September 2022

The intersection between morphology and pragmatics in EkeGusii, a Bantu language spoken in Kenya among the natives of Kisii and Nyamira Counties, is the concern of this paper. Besides the lean evidence of previous research on EkeGusii morphopragmatics, the argument is presented in four parts. The first examines the interplay between affixation and pragmatics, especially contextually sanctioned diminution and augmentation. This happens in the revelation of attitude at the lexical, and post-lexical levels, where in the latter, vowel lengthening is an alternative way of modifying degrees of augmentation and diminution. Diminution and augmentation also relate to style as manner with language, social relations, persuasion and euphemism in clitic-like groups, and augmentative prefixation where the function of the amplifier prefix is defined. The second part posits that metaphorical compounds acquire idiosyncratic meanings supported by context. The third part presents the meanings of iconic reduplicatives as isomorphic, and dependent on context. The final part delves into the portmanteau morph, a knotty problem as evidenced in EkeGusii, arguing that it can only be described as serving pragmatic functions with greater reliance on syntax and semantics, which in turn abet covert morphological change. The portmanteau morph, from a morphopragmatic viewpoint, is more of a question to ponder than a conclusion.
The relationship between fear of covid-19 and life satisfaction: coping strategies with covid-19 and perceived social support as mediators
Authors: Abdullah Manap , Cemal Karadaş
Published: September 2022

This study investigated the mediating role of coping strategies and perceived social support in the relationship between fear of COVID-19 and life satisfaction. The study adopted a quantitative approach with a correlational design. The study group included 729 participants, and of these participants, 347 were women (47.6%) and 382 were men (52.4%). To collect the data, a personal information form, multidimensional scale of perceived social support, coping with the pandemic scale and fear of COVID scale, and Life Satisfaction Scale were used. The data were collected online through Google Forms. Before the path analysis, assumptions such as multicollinearity and normality were checked, which showed that the data were suitable for the analysis. Nearly all the correlations between the variables were significant except the one between fear of COVID and life satisfaction. The path analysis suggested that there was no significant association between fear of COVID and life satisfaction. However, the life satisfaction of individuals with fear of COVID increases as they use more coping strategies and perceive a higher level of social support. The current study, conducted on individuals who were lonely with some social and personal problems during the pandemic, will contribute to the literature. Finally, some suggestions were given based on the findings.
Adult learners' motivators from instructors' perceptions: a case of a political science program in vietnam
Authors: Le Thanh Thao , Tran Thi Cam Tu , Vo Thi Kim Hue , Trinh Quoc Lap
Published: September 2022

Teaching adult learners is not an easy mission for instructors. Among many factors affecting adult learners' learning, motivation seems to be the most significant. Studies on adult learners' motivation, especially on Vietnamese ones who pursue political science programs to become leaders in government offices and in the private sector, are still limited. Accordingly, this current study was conducted to investigate what motivates adult learners to be successful in their learning. Forty-six instructors who have worked with adult learners in political science programs for at least five years participated in this study to provide their perceptions of adult learners' reasons for taking an advanced political science course. A sixteen-item questionnaire was used to collect the quantitative data on teachers' perception of learners' motivators, and two focus group interviews were conducted to gain an in-depth understanding of the motivators stimulating learners to get involved and thrive in their study program. According to the survey results, the instructor participants perceived the desire to serve the community and the country and the trust of beloved people as the primary motivators for encouraging adult learners to continue their learning. Additionally, personal advancement and selfinterest were also believed to have a remarkable impact on adult learners' learning motivation. The research context contributes to an explanation of why these motivators were highly perceived as adult learners' motivators. The results also stated the important role of institutional support for them to stay focused on their learning and foster the values of their school comeback.
Optimization of the Ahp Method in Determining the Location of Touristdestinations on the Island of Java, Indonesia
Authors: Winarso Widi , S Supardi , A Azizah , K Kuswantinah , S Su’aidy , Untari Dhian Tyas
Published: September 2022

Purpose: This study aims to map the pattern of tourist preferences in visiting tourist destinations on the island of Java
 
Theoretical framework: This research tries to make a tourist decision model in choosing a tourist destination on the island of Java with a mathematical method, namely Analytical Hierarchy Process (AHP).
 
Methodology: The sample data used is data sourced from the "Indonesian backpacker" group. Respondents were selected based on the criteria that they had traveled to three tourist destinations, namely; Jakarta, Yokjakarta, and Bandung. Data collection was carried out to obtain information and data related to this research. In this study, the researcher optimizes the calculation of the AHP method to determine the ranking of the existing alternatives so that it is hoped that the calculation results are more accurate than using the AHP method
 
Findings: Based on communal considerations (all criteria) with the AHP method in sequence; Jakarta (50,5%), Bandung (30,9%), and Yogyakarta (18,6%). The results showed that Jakarta became the main priority, then Bandung and respectively. Ease of access and completeness are the reasons for choosing a tourist destination on the island of Java.
 
Research implications: The quality of site transactions is closely related to the quality of human resources (HR) where in service products, humans become the mind product. HR in Tourism sector are all human aspects that support tourism activities, both tangible and intangible, which aims to meet the needs and create tourist satisfaction and have a positive impact on the economy, welfare, and environmental and cultural sustainability in a tourist area. Improving the quality of human resources is very important in improving the quality of tourist destinations.
 
Originality/value: Research on the model for selecting tourist destinations on the island of Java as the island with the most populous population in Indonesia has never been done before by other researchers
Studying the Effect of Employees’ Environment Awareness as an Intermediate Variable for the Relationship between Institutional Pressures and Intentions of Human Resources for Adoption of Green Information Techniques: An Exploratory Study of Micro-Companie
Authors: Khdair Wameedh A. , D. Jabbar Abd Aladheem
Published: September 2022

Purpose: The aim of the present research paper is to study the impact of institutional pressures derived from institutional theory on the intentions of human resources in micro companies to adopt green information technology. Besides, it aims at explaining the reasons why human resources in companies and research sample, are heterogeneous in their adoption of green information technology, even though they are under institutional pressures.
 
Theoretical Framework: The carbon footprint for micro-companies enlarges continuously for due to its an increasing use of information techniques in its all activities. Institutional pressures have increased on micro-companies pushing it toward letting human resources adopt green information techniques for mitigating negative impacts hit environment.
 
Design/Methodology/Approach: The quantitative design was adopted to collect data from employees working in micro-companies’ in southern Iraq for a sample of 181 employees through the questionnaire. The study sample was requested to give an answer to its items in accordance with 7 point Likert scale. As per data statistical analysis, through the use of Partial Least Squares.
 
Findings: that institutional pressures (forced, imitated & standard) collectively impact positively on intents of the study’s sample for adoption of a green information technique. Also, it was found that institutional pressures (forced, imitated & standard) impact positively employees’ environmental awareness. Then diagnosing the role of employees’ environmental awareness as a variable intermediating the relation between institutional pressures and intents for letting human resources adopt a green information technique.
 
Research, Practical & Social implications: Future studies can understandable that green information technology is an open arena for all researchers interested in the environment. Researchers can enter this field by raising study questions and employing and applying its variables to micro companies, or public sector organizations. They can expand the organizational theory by adding other intermediate or interactive variables and their effects on human resources’ intentions to adopt green information technology.
 
Originality/value:  Human resources in micro companies play a significant role in shaping the company’s legitimacy in its institutional field. Because micro companies appreciate the commencement time to adopt green information technology, and the place of practice. This requires enriching their knowledge of the challenges facing the environment by developing mandatory and voluntary programs to increase human environmental awareness and to get them engaged and directing their behavior towards this objective.
The possibility of Applying International Accounting Standards in the Public Sector (IPSAS) in the Iraqi Government Accounting System: Exploratory Research for the Opinions of Accountants at the University of Al-Muthanna
Authors: El-Toby Bushra Hassan Mohamed , Kareem Akeel Dakheel , Abd Waad Hadi
Published: September 2022

Purpose: This paper aims to use such standards to contribute to strengthening the accounting profession at the global level and provides financial disclosure that is easy to understand, treat and deal with, and hold government officials accountable for its basis.
 
Theoretical Framework: Rapid developments in the field of information technology and the trend toward global trade relations imposed the use of new tools to address the government accounting system applied in Iraq to improve the quality of financial information. In addition, reducing the manipulation of public money and rationalize the state's economic policies.
 
Design/Methodology/Approach: To achieve the research objectives, a questionnaire was designed and Distributed to an intentional sample of accountants, whose number reached (60) accountants.
 
Findings: The findings show the importance of IPSAS standards in presenting financial reports to help accountants obtain them quickly and thus achieve the efficiency and effectiveness of accounting work, correcting and strengthening decisions and ensuring their effectiveness systems.
 
Research Practical& Social implication: The contribution of our paper relies on investigating the General Accounting System (IPSAS) in the government accounting system in the field through doing a survey of the opinions of specialists at the University of Al-Muthanna as a field for conducting research, as well as an indication of the adequacy of laws, legislation and principles that regulate government accounting to ensure good practice of ( IPSAS ) standards.
 
Implications/Originality/Value: the possibility of applying international accounting standards in the public sector to its accounting systems.
Factors Influencing Small Medium Enterprise’s Behavior in Adopting E-fulfillment Services
Authors: Kurniasari Florentina , Gunawan Dennis , Utomo Prio
Published: September 2022

Purpose: Since the SMEs were the key players in these current digital businesses in Indonesia, the purpose of this study is to analyse the benefit in adopting the e-fulfillment services by considering the variable of technology acceptance model that was related with trust.

Design/Methodology/Approach: This research was used three exogenous variables, namely: perceived usefulness, perceived ease of use and perceived security and risks-free. In addition, the research considered the adoption in new e-fulfillment services platform as endogenous variable with trust as intervening variable. The data collected from the SME’s who are located in the Jakarta and its surrounding areas and further analyzed statistically using Structural Equation Model approach.

Findings: The key finding of this research was trust played a significant role in influencing the customer adoption of the e-fulfillment platform. The research also showed that perceived ease of used was the main factor in creating customer trust. The maximum usage of e-fulfillment services allowed the SME’s to focus more the product development and marketing activities.

Research, Practical & Social Implications: SME’s would enjoy strong business competitive positioning if they were able in adopting the e-fulfillment services.

Originality/Value: Since the concept of e-fulfillment services were quite new in Indonesia, the study recommends the needs to increase the awareness and knowledge to SME’s by ensuring the benefit of this new platform.
Muhasebe Meslek Mensuplarının Yalın Muhasebe Bilgi Düzeylerinin Ölçülmesi: Kars İli Örneği ( Measuring The Lean Accounting Knowledge Levels of Accounting Professionals: Sample of Kars Province)
Authors: Madak Ebru , Temelli Fatma
Published: September 2022

Bu çalışmanın amacı, Kars ilinde faaliyet gösteren muhasebe meslek mensuplarının yalın muhasebe bilgi düzeylerini demografik değişkenler açısından ölçmektir. Bu amaç doğrultusunda, Kars ilinde faaliyet gösteren Serbest Muhasebeci Mali Müşavirlere (SMMM) anket uygulanmıştır. Araştırmada elde edilen veriler; frekans analizi, ortalama, standart sapma, güvenilirlik analizi, faktör analizi, bağımsız örneklem t-testi ve tek yönlü varyans analizi (Anova testi) ile test edilmiştir. Analizlerin gerçekleştirilmesindeSPSS 26 istatistik paket programından yararlanılmıştır.Çalışmanın sonucunda; araştırmaya katılan muhasebe meslek mensuplarının yalın muhasebe bilgi düzeylerinin demografik değişkenler açısından anlamlı bir farklılık göstermediği tespit edilmiştir. Bununla birlikte, yalın muhasebe ile alakalı eğitim veya seminere katılan muhasebe meslek mensuplarının yalın muhasebe bilgi düzeylerinin yüksek olduğu belirlenmiştir.
Use of Danzhi Xiaoyao Powder in the Treatment of Diseases by Chief Physician Wang Defen: Case Examples
Authors: Luo Ying
Published: September 2022

Danzhi Xiaoyao powder was first introduced by Xue Ji, a Ming Dynasty physician, in the “Summary of Internal Medicine.” It is primarily used for treating the syndrome of liver depression transforming into heat and is widely used in the treatment of dermatology, internal medicine, gynecology, and other multi-system diseases. This medical prescription is aptly dispensed, its detoxification effect is strong, and it is a representative medical prescription for soothing the liver, strengthening the spleen and stomach, as well as eliminating heat stagnation. Chief Physician Wang Defen inherited the academic experience of the fifth batch of nationally known Chinese medicine experts, under the guidance of Professor Ji Haiwang, a notable Chinese medicine practitioner in Shaanxi Province and Professor Shi Bingyin, a renowned endocrinologist. Through follow-up studies, the various methods and empirical prescriptions of Danzhi Xiaoyao powder applied by Chief Physician Wang Defen in the treatment of common clinical diseases are summarized. They have been proven to have conclusive efficacy, thus providing guidance and reference for the dialectical treatment using traditional Chinese medicine.
Cost Management Strategy of Highway Engineering Construction Stage Using the List Pricing Model
Authors: Peng Zhenghong
Published: September 2022

Highway engineering requires higher investment and requires a long time of management compared to other construction projects. There are many factors that affect the project cost during the engineering construction stage of a highway. The effective development of cost management in the construction phase of highway engineering under the list pricing model can avoid unnecessary waste and help control the cost of highway engineering. However, there are still some problems in the development of cost management in the construction phase of highway engineering, which will affect the role of the list-based pricing mode in cost management. This paper explores and analyzes the advantages of the list pricing model and the problems existing in the cost management of the highway engineering construction stage under the list pricing model, and proposes effective management strategies to improve cost management of the highway engineering construction stage.
Mulheres e Governação Desportiva Nacional: Uma Abordagem Europeia. Guião de entrevista
Authors: Esteban Salvador María Luisa , Fernandes Emilia , Di Cimbrini Tiziana , Güngör Göksu Gonca , Jones Rachael
Published: September 2022

Este livro apresenta a transcrição e tradução de 52 entrevistas realizadas a mulheres dirigentes das Federações Nacionais de Desporto (FND) de cinco países europeus: Itália, Portugal, Espanha, Turquia e Reino Unido. As entrevistas foram gravadas em vídeo e realizadas entre março de 2019 e junho de 2022. O livro é um produto do projeto ERASMUS+, intitulado “Governação em organizações desportivas: uma perspetiva de género (GESPORT Project)”, e financiado pela Comissão Europeia. O objetivo deste livro é aumentar a visibilidade e a voz das mulheres presidentes, vicepresidentes e outros membros femininos das direções das FNDs, a fim de obter uma alargada sensibilidade em relação à igualdade de género na tomada de decisões em organizações desportivas. Assim sendo, com este livro, o projeto GESPORT pretende partilhar as diferentes experiências, sentimentos e pensamentos destas mulheres sobre os seus papéis nas direções desportivas, a discriminação e igualdade de género e as políticas e medidas de promoção da igualdade e inclusão de género.
Governação Corporativa nas Organizações Desportivas: Uma abordagem de género RELATÓRIO FINAL 2022
Authors: Esteban Salvador María Luisa , Di Cimbrini Tiziana , Fernandes Emilia , Güngör Göksu Gonca , Smith Charlotte
Published: September 2022

O projeto “Governação corporativa nas organizações desportivas: Uma abordagem de género” (doravante Projeto GESPORT) procura reforçar a igualdade entre homens e mulheres em posições de tomada de decisão, em organizações desportivas, na Europa. O primeiro objetivo do projeto é melhorar a acessibilidade das mulheres à direção de todas as federações desportivas ao abrigo das ações do programa Erasmus + Sport. Por outras palavras, o Projeto GESPORT visa divulgar conhecimentos relativamente à presença de mulheres em posições de tomada de decisão estratégica e, desta forma, contribuir para as políticas europeias de promoção e apoio de uma boa governação no desporto. Aqui, definimos género em termos binários, “masculino” e “feminino”. Contudo, reconhecemos que estes são termos ambíguos e com os quais nem todos se identificam. Por este motivo, refletiremos mais sobre o tema da identificação não-binária como identidade social e transgénero no desporto posteriormente, na secção do contexto do relatório, a seguir à introdução.
La corporate governance nelle organizzazioni sportive: un approccio di genere. Report finale 2022
Authors: Esteban Salvador María Luisa , Di Cimbrini Tiziana , Fernandes Emilia , Güngör Göksu Gonca , Smith Charlotte
Published: September 2022

Il progetto "La corporate governance nelle organizzazioni sportive: un approccio di genere" (di seguito progetto GESPORT), ha l’obiettivo di promuovere l'uguaglianza tra uomini e donne nei processi decisionali nelle organizzazioni sportive in Europa. Il fine ultimo è favorire l'accesso delle donne ai consigli direttivi delle federazioni sportive, coerentemente con le azioni previste per il mondo dello sport da Erasmus +. Allo stesso tempo, Il progetto GESPORT vuole contribuire alle politiche europee per rafforzare e sostenere il buon governo nello sport attraverso una maggiore conoscenza del ruolo femminile nei processi decisionali strategici. In questa sede abbiamo scelto di definire il genere in termini binari, come "maschio" e "femmina". Tuttavia, siamo consapevoli che si tratta di termini ambigui in cui non tutti possono o vogliono essere riconosciuti. Per questo motivo, una parte di questo report è dedicata a tratteggiare qualche riflessione sulla questione del non-binario come identità sociale e transgender nell
El gobierno corporativo en las organizaciones deportivas: un enfoque de género. Informe final 2022
Authors: Esteban Salvador María Luisa , Di Cimbrini Tiziana , Fernandes Emilia , Güngör Göksu Gonca , Smith Charlotte
Published: September 2022

El proyecto "Gobierno corporativo en las organizaciones deportivas: Un enfoque de género" (en adelante, proyecto GESPORT), pretende reforzar la igualdad entre hombres y mujeres en los ámbitos de decisión de las organizaciones deportivas en Europa. El objetivo principal del proyecto es mejorar el acceso de las mujeres a las juntas directivas de todas las federaciones nacionales deportivas en el marco de las acciones deportivas de Erasmus+. En otras palabras, el proyecto GESPORT pretende avanzar en el conocimiento de la presencia femenina en la toma de decisiones estratégicas y, con ello, contribuir a las políticas europeas de mejora y apoyo a la buena gobernanza en el deporte. Aunque hemos definido el género en términos binarios, como "masculino" y "femenino", reconocemos que se trata de términos ambiguos a los que no todas personas pueden o desean asignarse. Por ello, reflexionamos más sobre la cuestión de lo no binario como identidad social y la transexualidad en el deporte más adelante, en la sección de antecedentes del informe que sigue a la introducción.
Spor organizasyonlarında kurumsal yönetim: Cinsiyete dayalı bir yaklaşım. SONUÇ RAPORU 2022
Authors: Esteban Salvador María Luisa , Di Cimbrini Tiziana , Fernandes Emilia , Güngör Göksu Gonca , Smith Charlotte
Published: September 2022

"Spor organizasyonlarında kurumsal yönetim: Cinsiyete dayalı bir yaklaşım" projesi (bu kısımdan itibaren GESPORT projesi olarak anılacaktır), Avrupa'daki spor organizasyonlarının karar alma alanlarında kadınlar ve erkekler arasındaki eşitliği güçlendirmeyi amaçlamaktadır. Projenin öncelikli amacı, Erasmus + spor faaliyetleri kapsamında kadınların tüm spor federasyonlarının yönetim kurullarına erişimini iyileştirmektir. Diğer bir deyişle, GESPORT projesi stratejik karar alma süreçlerinde, kadınların varlığına ilişkin bilgileri geliştirmeyi ve bunu yaparak sporda yönetişimi iyileştirmeye ve desteklemeye yönelik Avrupa politikalarına katkıda bulunmayı amaçlamaktadır. Burada toplumsal cinsiyeti “erkek” ve “kadın” şeklinde ikili terimlerle tanımladık. Ancak bunların herkesin tanımlanamayacağı veya tanımlanmak isteyemeyeceği belirsiz terimler olduğunun farkındayız. Bu nedenle, girişten sonra gelen arka plan bölümünde, bir sosyal kimlik olarak ikili olmayan ve sporda transgender konusuna daha fazla değineceğiz
Epitweetr: Early warning of public health threats using Twitter data
Authors: Espinosa Laura , Wijermans Ariana , Orchard Francisco , Höhle Michael , Czernichow Thomas , Coletti Pietro , Hermans Lisa , Faes Christel , Kissling Esther , Mollet Thomas
Published: September 2022

Background

The European Centre for Disease Prevention and Control (ECDC) systematically collates information from sources to rapidly detect early public health threats. The lack of a freely available, customisable and automated early warning tool using data from Twitter prompted the ECDC to develop epitweetr, which collects, geolocates and aggregates tweets generating signals and email alerts.

Aim

This study aims to compare the performance of epitweetr to manually monitoring tweets for the purpose of early detecting public health threats.

Methods

We calculated the general and specific positive predictive value (PPV) of signals generated by epitweetr between 19 October and 30 November 2020. Sensitivity, specificity, timeliness and accuracy and performance of tweet geolocation and signal detection algorithms obtained from epitweetr and the manual monitoring of 1,200 tweets were compared.

Results

The epitweetr geolocation algorithm had an accuracy of 30.1% at national, and 25.9% at subnational levels. The signal detection algorithm had 3.0% general PPV and 74.6% specific PPV. Compared to manual monitoring, epitweetr had greater sensitivity (47.9% and 78.6%, respectively), and reduced PPV (97.9% and 74.6%, respectively). Median validation time difference between 16 common events detected by epitweetr and manual monitoring was -48.6 hours (IQR: −102.8 to −23.7).

Conclusion

Epitweetr has shown sufficient performance as an early warning tool for public health threats using Twitter data. Since epitweetr is a free, open-source tool with configurable settings and a strong automated component, it is expected to increase in usability and usefulness to public health experts.
Recurrent cardiac rhabdomyosarcoma with multiple metastases: A case report
Authors: Reyhanoglu Hasan , Edem Efe , Ozcan Kaan , Altınok Tayfun
Published: September 2022

Rhabdomyosarcoma, which accounts for 20% of all malignant tumors of the heart, is an aggressive tumor originating in the ventricular wall. These tumors are the second most common malignant primary tumor of the heart after angiosarcoma. Despite treatment options, such as surgical resection, radiotherapy, and chemotherapy, recurrence is common and mortality is high. Among these patients, survival with surgical resection is around six months to one year. In this case report, we discuss a patient who presented with recurrent rhabdomyosarcoma with distant metastasis after surgical intervention. A 56-year-old male patient who underwent left atrial mass excision and mitral valve replacement ten months prior was admitted with recurrent metastatic rhabdomyosarcoma.
Isolated cardiac hydatid cyst of the right ventricle
Authors: Ozdemir Ahmet Coskun , Akdogan Ali , Guven Kibar Yasar
Published: September 2022

A hydatid cyst is a parasitic disease that most commonly affects the liver and lungs: it rarely affects the heart: right ventricular involvement is even less common. A 33-year-old male patient with a cardiac cystic mass, detected during echocardiography, was evaluated. Early surgery was the best treatment option. A hydatid cyst is located in the right ventricular wall and detected during surgery. The cyst was drained and the defect in the right ventricle was quilted. Postoperative follow-ups occurred, and he was discharged with albendazole in good health.
EMERGING FROM QUARANTINE. THE NIGHT OF THE INTELLECTUALS
Authors:   Russian State University for the Humanities, Yanpol’skaya Yana G.
Published: September 2022

The article deals with the pandemic as an episode of intellectual history and a situation of reflection against the background of the “death of an intellectual”. The author proposes to question the very conditions of the possibility for philosophy’s response to the challenge of this or that current crisis in principle and the coronavirus pandemic in particular. The question is closely related to the phenomenon of the Intellectual, the crisis of which was announced by French researchers about forty years ago. Today one can talk about the simulation of its role and place in modern “reactions”, about the objective historical impossibility of reviving this figure and its inherent form of expression. The issue is considered based on the material of French intellectual history and criticism of the “media intellectual”. The starting point of the analysis is the political crisis in France in 2019, which falsely revived the forgotten structure of “intellectuals and power”. The author of the article draws attention to the similarity of the intellectual “calm” (reflexive inertia) of 1941 and 2021, suggesting to recall those forms of reflection that were involved by A. Malraux, J.-P. Sartre, J. Paulhan, M. Merleau-Ponty. The “reactions” of certain French intellectuals caused by the coronavirus crisis – E. Moren, R. Debray, J.-L. Nancy, B. Latour – reproduced in the article in the light of the interpretation of the pandemic as a “reductive situation” (M. Mamardashvily) with its inherent moralizing and neo-mania (R. Barthes). The author finds it problematic to appeal to criticism in the face of the “terror of the event” (M. Merleau-Ponty). Intellectuals themselves are a rare extinct phenomenon, which is important to consider in anticipation of their “response” in the face of the threat of a pandemic
PUBLIC LEGITIMATION OF POLITICAL POWER IN THE CONTEXT OF CIVIL SOCIETY TRANSFORMING IN MODERN RUSSIA
Authors:   Institute of Socio-Political Research of the Federal Center of Theoretical and Applied Sociology of the Russian Academy of Sciences, Velikaya Nataliya M.
Published: September 2022

The issues of legitimizing the political regime are of particular importance in the conditions of transitional societies, when the preservation of the sustainable development trend becomes the most important condition and basis for the preservation of national security. The subject of the article is the legitimization of political power due to the level of trust and loyalty of the Russian population to a number of socio-political institutions at the present stage. The analysis of the data of monitoring studies conducted at the ISPR of the Federal Research Center of the Russian Academy of Sciences allowed the author to state That in society there remains a significant gap between trust in the institution of presidential and parliamentary power, and that a high level of distancing from government institutions and moderate loyalty associated with the need to maintain formal “order” are reproduced at a low level of trust. Given that the public legitimacy of the Russian political system is based on the president’s ratings, which retain a high potential, it can be assumed that the pseudoalternative election model will be preserved in the near future. At the same time, the dynamics of the level of trust and sympathy for a number of political institutions suggests the limit of opportunities for growth in the existing conditions of a system with a limited role of parties, what both reduces the space of free political discourse and limits the possibility of choice for citizens, which will threaten the legitimacy of the political regime.
IMPACT OF THE CORONAVIRUS PANDEMIC ON THE PARTICIPATION OF RUSSIAN YOUTH IN THE ACTIVITIES OF YOUTH SOCIAL ORGANIZATIONS
Authors:   Russian Federation Security Guard Service Federal Academy, Kostenko Valerii V.
Published: September 2022

The ongoing process of the world globalization is having an increasing impact on Russia. The leading countries of the West world are trying to impose their political and economic views, moral and moral values, which negatively affects primarily youth and their participation in the activities of youth organizations. The spread of the coronavirus pandemic, which has an increasing impact on various aspects of the socio-political situation in Russia and the activities of both government and public structures, adds to the negative. The article considers issues of influence of consequences of pandemic of coronavirus on participation of young people in activities of youth social organizations, taking into account peculiarities of the value orientations of modern youth,. It analyzes “quarantine” forms of protest activity, their impact on the socio-political situation in the country. There are definitions for directions of the authorities efforts preventing the development of destructive manifestations in the protest activities of youth public organizations.
THE STRUCTURE OF RUSSIAN FILM FESTIVALS DURING THE PANDEMIC
Authors:   Bojole Research, Ryseva Aleksandra I.
Published: September 2022

The article covers the current situation with Russian film festivals. The author has developed a typology of film festivals, which contributed to the development of criteria for collecting up-to-date information about such festivals and creating a fresh database. It describes the social profile of the Russian film festival movement indicating the number of active festivals divided by different types along with the dynamics of their growth / decrease from 2019 to 2021. The author provides with a detailed description of the types and subtypes of movie festivals and categorizes them by the level of importance for filmmakers from various spheres as well as by the principles of their business operation and functioning. Another focus of the article is on the structure of the Russian festival movement and the dynamics of its change over the last three years together with certain adaptation strategies. In the last part of the article the author shows the analysis of the prominent filmmakers‘ opinions about the role of film festivals for the audience and for the industry.
THE POLITICAL ECONOMY OF DROUGHT AND THE MARGINALISATION OF THE POOR
Authors: Rao C. Srinivasa
Published: September 2022

The general theme of this paper is that drought, though an agro-climatic phenomenon, has phenomenon has far reaching socio-economic consequences. The adverse impact of drought on the poorer sections is devastating, while the richer classes may actually benefit from it. There actually may emerge a emerge, a new middle class consisting of the middle peasantry, rich families and traders in the countryside and a section engaged in urban based trading, industrial and services sector.
NATURAL REGENERATION CAPACITY OF VITELLARIA PARADOXA (SHEA TREE) ON THE HILLS OF BASSAR (NORTH-TOGO)
Authors: Dermane Wagbe Tchapo , Djangbedja Minkilabe , Kamou Hodabalo
Published: September 2022

As the consequence of anthropic pressure along with climatic factors, the vegetation of the hills of Bassar is degrading day after day and a regression of many woody species is observed. Vitellaria paradoxa is a highly valued multi-use species, but it is threatened with extinction in the area. The "bell" and "L" shapes of the diameter class distribution histograms reflect aging and/or disturbed populations. Stand disturbance is illustrated by the low proportion of large diameter class individuals. The "L" shape reveals an advanced state of degradation characterized by a near absence of large diameter trees. The study of the natural regeneration of Vitellaria paradoxa on the hills of Bassar shows that the density of regeneration by seedlings, shoots and suckers depend on the diameter of the individual stem. The larger the diameter increases, the higher the density of seedlings becomes. However, plantlets stemming from seedlings are higher, and weaker from suckers and shoots. The density of Vitellaria paradoxa seedlings is lower in shrub savannahs than in tree savannahs. The analysis of variance showed that whether under the crown or outside the crown, there was a significant difference between individuals from regeneration in all the formations studied. In the inventory plots, the densities of young trees are equally variable under the crown and outside the crown as those of large trees.
AN EMPIRICAL STUDY ON INVESTORS’ PREFERENCE FOR MUTUAL FUND INVESTMENT
Authors: Nag Rajdeep , Chakraborty Dr. Sudip , Dey Dr. Nikhil Bhusan
Published: September 2022

Savings and investment are important facets of a person’s life. These are the steps towards financial independence and well-being. When it comes to investment there are plethora of risky high return options as well as safe but low return options. Investment in high return options is considered necessary to create wealth and beat the negative impact of inflation. This calls for investment in risky capital market. In this context mutual funds have become one of the viable options for investors. This research article is an attempt to study the preference for mutual fund investment by the retail investors of Guwahati city of Assam. The study revealed that mutual funds has become one of the popular investment options among investors in Guwahati.
AN AYURVEDIC PERSPECTIVE OF DYSMENORRHOEA WSR TO KASHTARTAV
Authors: Karale Bhagwan , Bawane Vishnu
Published: September 2022

Due to sedentary lifestyle, improper diet and lack of exercise women facing many health problems. Dysmenorrhoea is one of the biggest health issues. In simple words dysmenorrhoea can define as a painful menstruati(Fawells cramp, labour like pain in lower abdomen. In Ayurvedic samhita, there is description of kashtartav. We can correlate that with Dysmenorrhoea.In this review study, we described Dysmenorrhoea with special references to kashtartav. We collect all references from all available texts, samhitas, internet links and previous thesis and Research papers.