bluuebunny/crossref_metadata_2025 huggingface dataset:
Closure of pilonidal sinus by the modified off-midline method in the Kurdistan Region, Iraq
Authors: Hawezy Dawan , Kareem Azhi
Published: December 2022

Background and objective: Sacrococcygeal pilonidal sinus disease is an inflammation in the natal cleft of the sacrococcygeal region, which develops to abscesses and sinus formation. The incidence of sacrococcygeal pilonidal sinus disease notably increased in the last 50 years, however, there is no accurate data about the frequency of the disease and incidence rate among the Kurdistan region-Iraq population. In this study, we have introduced a simplified off-midline surgical technique without flap reconstruction. The main objective was to find out the rate of postoperative complications, hospitalization time, the recovery time to daily activity and work, and esthetic satisfaction. Methods: This study was conducted in Kurdistan region, Iraq from March 2016 to September 2019 on individuals suffering from sacrococcygeal pilonidal sinus disease. Two hundred ninety-eight individuals from different gender and ages enrolled for operation by modified simple closure of sacrococcygeal pilonidal sinus disease. Results: The median age of the patients was 22.4 years (24.1 male and 20.5 female). 33.9% of our patients were female students (P = 0.002). Most of the patients (89.2%) did not have postoperative complications. However, wound infection was detected in 3.0% of patients. Sacrococcygeal pilonidal sinus disease recurred in 5.4% of patients; furthermore, the disease recurred twice in 7 females (2.4%). All the recurrences happened in the patients that had a severe form of sacrococcygeal pilonidal sinus disease. Conclusion: Significant number of our patients were students, and female students for unclear reasons are at risk in our region. The post-surgical complications only occur in patients with a severe form of sacrococcygeal pilonidal sinus disease. In terms of simplicity, hospitalization time, the recovery time to daily activity and work, esthetic satisfaction, and post-surgical complications, our surgery technique was superior to other open wound surgery such as V-Y Advancement flap, and Karydakis flap.
Short-stay sutureless total thyroidectomy
Authors: Abdulhamid Sabat , Al Dabbagh Ali
Published: December 2022

Background and objective: Thyroid surgery has traditionally been done on an inpatient basis. With the advent of minimal access techniques. This study aimed to assess the outcome of short-stay total thyroidectomy in comparison with a longer stay in terms of postoperative complications. Methods: This was an observational comparative study which was carried out at the surgical units of Erbil of Rizgary Teaching Hospital and private hospitals in Erbil city. The data were collected in the period between January 2017 and March 2021. Data of 192 patients’ records who underwent thyroidectomy were collected. Results: In this study, 33 (17.1%) patients were males while 159 (82.8%) were females. Out of 192 patients, 137 underwent sutureless technique while 55 of them underwent sutured way of hemostasis. Majority of patients 173 (90.1%) were discharged before 23 hours, while 19 (9.9%) were discharged after 23 hours. Significantly, higher percentage of males (24.2%) stayed more than 23 hours in the hospital compared with 6.9% of females (P = 0.006). The majority of indications with goiter, Graves’ disease, toxic nodule and solitary stayed between 12-23 hours while half of those with cancer stayed more than 23 hours (P = 0.023). Conclusion: Short-stay thyroid surgery is a feasible and safe procedure when combined with sutureless technique: this returns to overall less postoperative complications; day-case and short-stay procedures account for an expanding area of modern-day surgery.
Mass‐Spec, Cryo‐EM and AI join forces for a close look at the transporter complex in cilia
Authors: Ishikawa Takashi
Published: December 2022

The intraflagellar transport (IFT) complex transports components between the cytoplasm and the ciliary tip. Two studies now report on the atomic structure of IFT‐B, the core of IFT, using cutting‐edge technology, such as cross‐linking mass spectrometry (MS), cryo‐electron tomography (cryo‐ET) and Alphafold2‐enabled AI‐based folding prediction. The 3D structure of IFT‐B reveals how the 15 component proteins are arranged to stabilize this gigantic complex and suggests a dynamic interplay between the proteins.
CO and PM10 Prediction Model based on Air Quality Index Considering Meteorological Factors in DKI Jakarta using LSTM
Authors: Wattimena Emanuella M C , Annisa Annisa , Sitanggang Imas Sukaesih
Published: December 2022

Purpose: This study aimed to make CO and PM10 prediction models in DKI Jakarta using Long Short-Term Memory (LSTM) with and without meteorological variables, consisting of wind speed, solar radiation, air humidity, and air temperature to see how far these variables affect the model.Methods: The method chosen in this study is LSTM recurrent neural network as one of the best algorithms that perform better in predicting time series. The LSTM models in this study were used to compare the performance between modeling using meteorological factors and without meteorological factors.Result: The results show that the use of meteorological predictors in the CO prediction model has no effect on the model used, but the use of meteorological predictors influences the PM10 prediction model. The prediction model with meteorological predictors produces a smaller RMSE and stronger correlation coefficient than modeling without using meteorological predictors.Novelty: In this paper, a comparison between the prediction model of CO and PM10 has been conducted with two scenarios, modeling with meteorological factors and modeling without meteorological factors. After the comparative analysis was done, it was found that the meteorological variables do not affect the CO index in 5 air quality monitoring stations in DKI Jakarta. It can be said that the level of CO pollutants tends to be influenced by factors other than meteorological factors.
Cabergoline-associated valvulopathy of the tricuspid valve in the treatment of prolactinoma
Authors: Hayes Annabelle G , Shirazi Masoumeh G , Thiyagarajah Anand , Torpy David J , De Sousa Sunita M C
Published: December 2022

Cabergoline-associated valvulopathy (CAV) is defined by the echocardiographic triad of moderate or severe regurgitation, valvular thickening and restricted valvular motion. While it is a well-described complication of dopamine agonist therapy in Parkinson’s disease, only three convincing cases of CAV have previously been described in the treatment of prolactinoma, with none involving the tricuspid valve. We describe a case of CAV affecting the tricuspid valve, ultimately resulting in the patient’s death. The novel finding of CAV affecting the tricuspid valve suggests a possible link between confirmed cases of CAV and the echocardiographic surveillance studies of cabergoline-treated prolactinoma patients which have mostly demonstrated subclinical tricuspid valve changes. The risk of CAV, although small, prompts a mindful prescription of dopamine agonist therapy for prolactinomas and consideration of measures to minimise cabergoline exposure. The cumulative cabergoline doses and duration of therapy associated with CAV in published cases exceed what has been evaluated in case series and surveillance studies, underscoring the importance of case reports in understanding CAV.
Synthesis and Antibacterial Activity of 1,3,5,7-Tetrahydroxy-9,10-Anthraquinone and Anthrone Derivatives
Authors: Nurbayti Siti , Mujahidin Didin , Syah Yana Maolana
Published: December 2022

In this research, the synthesis of 1,3,5,7-tetrahydroxy-9,10-anthraquinone (1) and two anthrone derivatives, 1,3,5,7-tetrahydroxy-10H-anthracene-9-one (2) and 1-hydroxy-3,5,7,9-tetramethoxyanthracene (3) has been done. Compound 1 was synthesized by a symmetrical condensation reaction of 3,5-dihydroxybenzoic acid in concentrated sulfuric acid. Reduction of the carbonyl group in compound 1 with SnCl2/HCl-HOAc affords compound 2. Compound 3 was prepared by modifying the hydroxy groups of compound 2 by a methylation reaction. The synthesized compounds were identified using nuclear magnetic resonance spectroscopy (NMR) and a high-resolution mass spectrometry (HR-ESI-MS). The antibacterial activity test of the synthesized compounds against four pathogenic bacteria, Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Salmonella typhi, was carried out using the microdilution method. Compound 3 showed moderate activity against B. subtilis, E. coli and S. typhi with a MIC value of 37.5 µg/mL. Moderate activity was also shown by compound 2 against S. aureus, while compound 1 showed weak activity with a MIC value of 75 µg/mL against the four test bacteria.
Antibacterial and Antioxidant Activity of Endophytic Bacteria Isolated from Hibiscus tilaceus Leaves
Authors: Sarjono Purbowatiningrum Ria , Anggraeni Aulia , Monita Afiina Putri , Asy’ari Mukhammad , Ismiyarto Ismiyarto , Ngadiwiyana Ngadiwiyana , Prasetya Nor Basid Adiwibawa
Published: December 2022

Antibacterial is a compound that inhibits or kills bacteria, especially infectious pathogenic bacteria. Antioxidants are compounds to inhibit the activity of free radicals in the body. The leaf extract of the waru plant (Hibiscus tiliaceus) is reported to have antibacterial, antioxidant, and anti-inflammatory activity. Bioactive compounds obtained from plants generally require a lot of plant availability and large areas for growth and take a long time. One solution to solve this problem is to isolateendophytic bacteria from plants. Endophytic bacteria are bacteria that live symbiotically in the host tissue so that they can produce the same bioactive compounds as the host. In the study, several stages were carried out, including isolation of endophytic bacteria from hibiscus leaves, gram-staining of bacteria, secondary metabolites production, antibacterial activity analysis by disk method,antioxidant activity analysis by DPPH free radical scavenger method, phytochemical screening, and identification of genotypic endophytic bacteria. Isolates of endophytic bacteria from Hibiscus tiliaceus leaves were obtained in cocci. They formed gram-positive bacteria with the closest relationship with Staphylococcus warneri strainAW 25 and Staphylococcus pasteuri strainATCC 51129. Endophytic bacteria from the Hibiscus tiliaceus leaves produce secondary metabolites containing alkaloids and saponins that can inhibit the growth of Staphylococcus aureus and Salmonella typhi and can be an antioxidant agent.
Lignan (+)-Piperitol-γ,γ-Dimethylallylether from Stem Bark of Zanthoxylum rhetsa (Roxb.) DC (Rutaceae)
Authors: Ruchiyat Ruchiyat , Naini Al Arofatus , Herlina Tati , Musthapa Iqbal , Supratman Unang
Published: December 2022

Lignans are a group of phenylpropanoid dimers in which the phenylpropane units are linked by their propyl side chains' central carbon (C8). Lignans have various biological activities, including antiviral, anticancer, cancer preventive, and cytotoxic. Zanthoxylum rhetsa (Roxb.) DC is a tree with prickly branchlets belonging to the Zanthoxylum genus, commonly known as panggal buaya in Indonesia. Asian tribes have used this plant as traditional medicine. In this study, (+)-piperitol-γ,γ-dimethylallylether, a furofuran lignan, was successfully isolated. The chemical structure of compound 1 was determined based on spectroscopic data, including 1D- and 2D-NMR, mass spectroscopy, and by comparing with previous spectral data. In addition, compound 1 was tested for its cytotoxic activity against MCF-7 breast cancer cell lines in vitro and showed weak activity with the IC50 value of 261.37 µg/mL.
Nimonol from Chisocheton macrophyllus (Meliaceae) Seeds and Their Cytotoxic Activity against P-388 Leukaemia Cells
Authors: Nurlelasari Nurlelasari , Huspa Desi Harneti P. , Maharani Rani , Darwati Darwati , Mayanti Tri , Farabi Kindi , Hanafi Muhammad , Supratman Unang
Published: December 2022

The Chisocheton genus belongs to the Meliaceae family which produces various structures and activities of compounds, such as antimalarial, antimicrobial, antitumor, anti-inflammatory, and cytotoxic. This plant has 53 species that are spread in tropical and sub-tropical forests, including Indonesia. Chisocheton plants have been known as plants that produce limonoids, namely triterpenoid compounds that have been modified to lose four terminal carbons (tetranortriterpenoids). One of the species whose phytochemical reports are still few and interesting for research on limonoid content is Chisocheton macrophyllus. Chisocheton macrophyllus is a tall plant that grows in the rainforest in the northern part of the island of Sulawesi, Indonesia, has the regional name ma aa, gula, pasak lingga, gending, ta suea, bekak, or pithraj tree. This paper will describe a limonoid compound, namely nimonol which has been isolated from Chisocheton macrophyllus. Nimonol is known to have the molecular formula C28H36O5 from a group of havanensin. The structure was determined by spectroscopic methods UV, IR, 1D-NMR (1H-NMR, 13C-NMR, and DEPT), 2D-NMR (1H-1H COSY, HMQC, and HMBC), and mass spectroscopy.
K průběhu henleinovského povstání na Osoblažsku a ve Městě Albrechticích v září 1938
Authors: Kolář Ondřej
Published: December 2022

The study describes and analyses the progress of the pro‑Nazi uprising of the German population of the Osoblažsko promontory and the city of Albrechtice in September 1938. The research is primarily based on the records from the post‑war Czechoslovak investigation and then on German sources from the period of Nazi occupation. Attention is paid to the social and professional structure of the insurgent leadership as well as the role of imperial institutions. The study also seeks to analyse the relationships between the components of the insurgent apparatus (party leadership, local public officials, command corps of paramilitary formations and other). Another area of research is the defence strategies and self‑stylization of the insurgents during the post‑war investigation. The course of events described is perceived within a wider strategic and political context
Dissemination of epidemic ST239/ST241-t037-agrI-SCCmecIII methicillin-resistant Staphylococcus aureus in a Tunisian trauma burn intensive care unit
Authors: Raddaoui Anis , Chebbi Yosra , Bouchami Ons , Frigui Siwar , Messadi Amen Allah , Achour Wafa , Thabet Lamia
Published: December 2022

Methicillin-resistant Staphylococcus aureus (MRSA) is an important pathogen causing health care-infections in the world, especially in burns. The aim of this study was to assess the extent of dissemination of MRSA isolated from burn patients in Burn Intensive Care Unit in Tunisia and to evaluate the frequency of virulence and antibiotics resistance genes. Among the 72 S. aureus isolates analyzed in the study, 54% were MRSA. The majority of MRSA (94.8%) were multidrug resistant and they had a high resistance rates to kanamycin (94.8%), tobramycin (90%), tetracycline (94.8%) and ciprofloxacin and rifampicin (87%, each). The gene aac(6′)-Ie-aph(2″)-Ia conferring resistance to kanamycine and tobtamycin were detected in all isolates and the aph(3′)-Ia gene conferring resistance to gentamicin were detected in 2.8% of resistant isolates. Tetracycline resistance genes tet(M), tet(K) and tet(L) were detected in 100%, 10.8% and 2.8% of the isolates, respectively. The SCCmec type III and the agr type I were the most predominant (69.2% and 90%, respectively). The 27 SCCmecIII-agrI isolates were clustered into two PFGE types A and B. The two representative isolates of PFGE clusters A and B belonged to ST239-t037 and ST241-t037 respectively. As conclusion, our results showed a high prevalence of MRSA in trauma burn intensive care unit belonging to two multidrug resistant clones ST239/ST241-agrI-t037-SCCmecIII MRSA. We also demonstrated that MRSA was disseminated between burn patients.
Splenic hamartoma in a patient with peripancreatic arterial arcades: A case report
Authors: Zsély Boglárka , Rónaszéki Aladár Dávid , Tóth Ambrus , Bakos Bence , Székely Eszter , Győri Gabriella , Bérczi Viktor , Kaposi Pál Novák
Published: December 2022

Splenic hamartoma is a rare benign vascular lesion of the spleen. A splenic mass was incidentally detected in an asymptomatic 65-year-old male during an abdominal ultrasound scan. The workup of the splenic lesion included an abdominal CT angiography (CTA), contrast-enhanced ultrasound (CEUS), and microvascular flow imaging Doppler sonography. The CT scan confirmed that the splenic mass had benign characteristics, and its contrast enhancement was similar to the spleen. The CEUS was able to rule out the possibility of hemangioma. Meanwhile, chronic compression of the celiac trunk and the filling of the splenic artery from collaterals were also detected on CTA. The imaging studies suggested a splenic hamartoma, and the diagnosis was confirmed by the result of a fine needle aspiration biopsy.
PRAKTIK SERBA 10.000 DI APLIKASI SHOPEE MENURUT HUKUM EKONOMI SYARIAH DAN PERATURAN MENTERI SOSIAL NOMOR 12 TAHUN 2019 TENTANG PENYELENGGARAAN UNDIAN GRATIS BERHADIAH
Authors: Sya'bana Ramdani Mugni
Published: December 2022

This study aims to determine the mechanism of the program which is then linked to the Regulation of the Minister of Social Affairs Number 12 of 2019 concerning the Implementation of Free Lottery with Prizes. Based on the results of the study, it can be concluded that the program can be followed by Shopee users and follows the applicable terms and conditions, when viewed from the process there are several elements of interrelated contracts, such as buying and selling, gharar, gambling, sweepstakes, and prizes. Shopee all 10,000 contains elements of gharar but gharar yasir, or a little gharar. After further analysis, this is included in the practice of lottery prizes. The prize itself is included in the tabarru contract, which if there is gharar yasir in the tabarru contract, it is allowed. The practice of all 10,000 in the Shopee application which is linked to the Minister of Social Affairs Regulation Number 12 of 2019 concerning the Organizing of Free Sweepstakes with Prizes, the researcher sees the suitability between Shopee of 10,000 and the regulation, because the important things that have been regulated by the regulation have been carried out by Shopee. Penelitian ini bertujuan untuk mengetahui mekanisme program tersebut kemudian dihubungkan dengan Peraturan Menteri Sosial Nomor 12 tahun 2019 Tentang Penyelenggaraan Undian Gratis Berhadiah. Berdasarkan hasil penelitian, dapat disimpulkan bahwa program tersebut dapat diikuti oleh pengguna Shopee serta mengikuti syarat dan ketentuan yang berlaku, jika dilihat dari prosesnya terdapat beberapa unsur akad yang saling berkaitan, seperti jual beli, gharar, judi, undian, serta hadiah. Shopee serba 10.000 mengandung unsur gharar akan tetapi gharar yasir, atau gharar yang sedikit. Setelah dianalisa lebih jauh ini termasuk ke dalam praktik undian berhadiah. Hadiah sendiri termasuk akad tabarru’ yang mana jika terdapat gharar yasir dalam akad tabarru’ maka diperbolehkan. Praktik serba 10.000 di aplikasi Shopee yang dihubungkan dengan Peraturan Menteri Sosial Nomor 12 Tahun 2019, ada kesesuaian antara Shopee serba 10.000 dengan Peraturan tersebut, karena hal-hal penting yang sudah diatur oleh peraturan tersebut sudah dijalankan oleh pihak Shopee.
PRAKTIK JUAL BELI PRE ORDER DENGAN SISTEM ONLINE
Authors: Utami Indrianti Putri
Published: December 2022

The practice of buying and selling online is a buying and selling transaction carried out through modern technology whose validity depends on whether or not the pillars and conditions that apply in buying and selling are fulfilled. Pre-order buying and selling transactions only have online catalogs of goods found on websites or social media. This study aims to determine the practice and implementation of buying and selling pre-orders with an online system at the Bylo.id and Gerai.aliyah online stores. And knowing the perspective of Sharia Economic Law on buying and selling pre-orders with the online system at the Bylo.id and Gerai.aliyah online stores. The method used in this research is descriptive research method, a method that is intended to collect information about the object of research. The results of the study conclude that the practice and implementation of buying and selling pre-orders with the online system at the Bylo.id and Gerai.aliyah online stores is carried out by pre-orders or orders made through the website or chat, then both parties agree on the price, payment system, and delivery. and buying and selling preorders with the online system at the Bylo.id and Gerai.aliyah online stores have fulfilled the pillars and conditions for buying and selling istishna'. Praktik jual beli online merupakan transaksi jual beli yang dilakukan melalui teknologi modern yang keabsahannya tergantung pada terpenuhi atau tidaknya rukun dan syarat yang berlaku dalam jual beli. Transaksi jual beli pre order hanya memiliki katalog barang online yang terdapat di website atau media sosial. Penelitian ini bertujuan untuk mengetahui praktik dan implementasi jual beli pre order dengan system online di took online Bylo.id dan Gerai.aliyah. Dan mengetahui perspektif Hukum Ekonomi Syariah terhadap jual beli pre order dengan sistem online di toko online Bylo.id dan Gerai.aliyah. Metode yang digunakan dalam penelitian ini adalah metode penelitian deskriptif, metode yang dimaksudkan untuk mengumpulkan informasi mengenai objek penelitian. Hasil penelitian menyimpulkan bahwa praktik dan implementasi jual beli pre order dengan sistem online di toko online Bylo.id dan Gerai.aliyah dilaksanakan dengan pre order atau pesanan yang dilakukan melalui website atau chatting, lalu kedua belah pihak bersepakat atas harga, sistem pembayaran, dan pengirimannya dan jual beli pre order dengan sistem online di toko online Bylo.id dan Gerai.aliyah telah memenuhi rukun dan syarat jual beli istishna’.
PELAKSANAAN JUAL BELI MAKANAN MENGGUNAKAN FITUR OVO PADA APLIKASI GRABFOOD PADA MASA PANDEMI COVID-19 DALAM PERSPEKTIF FIQH AL-BAI’
Authors: Safitri Neng Murtapi'ah
Published: December 2022

Corona virus or severe acure respiratory syndrome coronavirus 2 (SARS-CoV-2 / Covid-19) is a virus that can attack the respiratory system, severe lung infection which can cause death. The corona virus can spread from one human to another very quickly, so that the economy during the pandemic was a little shaken due to the physical distancing policy, hampers trading activities and direct business transactions, morever dominan busniness actors exist in the informal sector and their businesses are in the form of micro, small and medium enterprises (MSME) which depend on daily turnover. The purpose of this research is to find out: 1) Food purchase mechanism with payment using the OVO feature on the GrabFood application during the Covid-19 pandemic at Al-Ihsan Islamic Boarding School Cibiru Hilir, Bandung Regency. 2) A riview of sharia economic law on the application of multicontract food purchases with payments using the OVO feature on the GrabFood application during the Covid-19 pandemic at the Al-Ihsan Islamic Boarding School Cibiru Hilir, Bandung regency. This research uses descriptive analytical method by using the results of previous studies as data sources which are described using literature study techniques and analyzed using a qualitative analysis approach, namely research used to examine the condition of objects in the field scientifically. The results of the analysis show that the implemantion of buying and selling food using the OVO feature in the GrabFood application during the Covid-19 pancemic is in accordance with the procedures determined by the goverment and can be done according to islamic law. Keywords: buying and selling during the Covid-19 pandemic; OVO payments, GrabFood. Tujuan penelitian ini adalah untuk mengetahui: 1) mekanisme jual beli makanan dengan pembayaran menggunakan fitur OVO pada aplikasi GrabFood masa pandemi Covid-19 di Pondok Pesantren Al-Ihsan Cibiru Hilir Kabupaten Bandung. 2). Tinjauan hukum ekonomi syariah terhadap penerapan multi akad pembelian makanan dengan pembayaran menggunakan fitur OVO pada aplikasi GrabFood masa pandemi Covid-19 di pondok pesantren al-ihsan cibiru hilir kabupaten bandung. Penelitian ini menggunakan metode deskriptif dengan menggunakan hasil penelitian terdahulu sebagai sumber data yang di deskripsikan menggunakan terknik studi pustaka dan di analisis dengan menggunakan pendekatan analisis kualitatif yaitu penelitian yang digunakan untuk meneliti kondisi objek di lapangan secara ilmiah. Hasil analisis menunjukan bahwa pelaksanaan jual beli makanan dengan menggunakan fitur OVO pada aplikasi GrabFood masa pandemi Covid-19 ini telah sesuai dengan prosedur yang telah ditentukan oleh pemerintah dan boleh dilakukan menurut hukum ekonomi syariah.
FIQH AL-BAI'S REVIEW OF ONLINE BUYING AND SELLING IN SPECIAL GROUPS ON FACEBOOK PLATFORM
Authors: Meirani Nadia , Komalasari Retno
Published: December 2022

Online buying and selling activities on the Facebook platform specifically for residents of Grand Cikarang City housing under the name of the Online Market group "Pasar Khusus COD Grand Cikarang City". With the development of online buying and selling, various kinds of risks arise that will haunt users, especially buyers, such as fraud, the obscurity of goods (gharar), incompatibility of goods and prices that reach the hands of the consumers, and so on. The purpose of this study is to find out the mechanism of buying and selling online in special groups on the Facebook platform and to find out the harmonization of Sharia Economic Law with buying and selling online in special market groups on the Facebook platform. The research method used in this research is a descriptive research method with qualitative data types. The results obtained in this study can be concluded that the implementation of online buying and selling in special groups on the Facebook platform uses a salam contract. There are cases where there is often uncertainty in terms of goods, prices, and the lack of certainty for the buyer to return the goods.
Designing Research Result-Based Arabic Pragmatic Learning Module On Politeness Principles And Strategies
Authors: Arifianto Muhammad Lukman , Kholisin Kholisin , Ridwan Nur Anisah , Izzudin Iqbal Fathi , Mujahidah Zulfa Azalia , Muhtar Siti Nuraeni
Published: December 2022

In the last decade, many studies on politeness in Arabic have been published on various platforms, but until now the results have not been systematically compiled and used as a module or teaching material. In addition, Arabic pragmatics teaching materials, especially regarding politeness principles and strategies, currently do not refer much to the results of the latest research, even though the results of these studies can be used as a basis in the context of applying, testing, or even developing a theoretical framework on Arabic politeness. Therefore, this study aims to design Arabic pragmatics learning modules, especially concerning politeness in Arabic by utilizing the results of these studies. It is assumed that the development of research-based learning modules can enrich learning materials with the latest findings. By utilizing content and thematic analysis, the research results are analyzed systematically and then designed as a learning module based on the lesson plan that has been set. The result shows a bunch of research about politeness in Arabic published in scientific journals and digital repositories. Almost all research refers to the remarkable theoretical framework of politeness principles proposed by Leech (1983), as well as politeness strategies proposed by Brown & Levinson (1987). Although both are relatively old-school frameworks, they still seem relevant to been implemented by some researchers to date. Furthermore, a systematic study of the results of these studies was then composed and designed into an Arabic pragmatic learning module, especially on the topic of linguistic politeness principles and strategies.
Arabic Language Learning System Based On SPADA DIKTI Indonesia
Authors: Rachmawati Miatin , Nugrahawan Ahmad Rizki
Published: December 2022

In this researcher will try to provide one of the lessons that attracts students' attention, one of which is the implementation of the SPADA DIKTI account which attracts attention and will find out the effectiveness of the SPADA DIKTI application on this platform, the research method used qualitative research with approach data in this study were included descriptions the primary data source which is carried out with a data collection technique is more on observation. Based on the explanation and data analysis, it was found that: By using an E-Learning. This In this special education menu there are several things related to learning, starting from Homepage, My courses, Vcon, Assigment, Exams, logbook, and presences. Here the researcher will explain one by one the steps of E-Learning at this higher education, especially in learning psycholinguistics courses. In this system the teacher can see the effectiveness of a learning system, the steps in applying a learning system, especially in the E-Learning system, can also help to monitor the seriousness of students take part in learning, especially psycholinguistics starting with the application of Spada Dikti, uploading materials, evaluations and student attendance lists, all neatly and effectively in learning the SPADA DIKTI learning system.
Tashawwurāt Al Thalabah ‘An Ta’līm Al Qawā’id Al ‘Arabiyyah Wa Ta’allumihā Al Qāim ‘Alā Al Kharāith Al Dzihniyyah Ba’da Jāihah Covid-19
Authors: Muna Wa , Hamzah Hamzah , Aminudin Aminudin , Mahyaddin Fikriyah , Zulaeha Zulaeha
Published: December 2022

Pengajaran tata bahasa Arab di era pandemi Covid-19 berbasis internet di Indonesia tidak sepenuhnya mendukung penggunaan dan pemanfaatannya oleh semua perguruan tinggi dalam proses belajar mengajar di dalamnya kecuali penggunaannya secara mengejutkan dan otomatis sesuai dengan kondisi yang dibutuhkan. Tidak memungkinkan proses belajar mengajar berlangsung tanpa Internet. Ini adalah ketika siswa mengklaim bahwa mereka kehilangan banyak hal di universitas dalam hal memahami materi pelajaran, uang mereka, dan waktu mereka yang berharga. Dalam hal ini peneliti menelusuri hal tersebut bertujuan untuk mengetahui tanggapan dan persepsi mahasiswa Jurusan Bahasa dan Sastra Arab STAIN Majene Sulawesi Barat terhadap proses belajar mengajar tata bahasa Arab berdasarkan peta mental yang diajarkan dan dipelajari oleh mereka di universitas. Penelitian ini merupakan penelitian kuantitatif, dan untuk jenisnya merupakan penelitian survei yang dilakukan oleh peneliti di kalangan mahasiswa Jurusan Bahasa dan Sastra Arab. Metode pengumpulan dilakukan dengan mengisi kuesioner yang dibagi kepada mereka untuk mengetahui tanggapan dan persepsi mereka tentang proses belajar mengajar berdasarkan pengajaran di universitas secara luring setelah pandemi Covid 19. Adapun persepsi mereka tentang pengajaran dan pembelajaran berdasarkan itu, mereka menyebutkan bahwa itu dapat memudahkan mereka untuk memahami mata pelajaran yang dipelajari di universitas dengan cepat dan efisien. Selain itu, mereka menyatakan sangat efektif dan menghemat waktu dalam memahami materi pelajaran.
Quantitative Analysis of Ceramics and the Formation of the Archaeological Record in Madinat Ilbirah (Granada, Spain)
Authors: Jiménez Puertas Miguel
Published: December 2022

This paper offers a study of a particular assemblage of ceramics retrieved in a pit in the Islamic town of Madinat Ilbirah (Granada, Spain) to analyse the processes of formation of the archaeological record. This can in turn provide interesting information on the patterns of use and discard of ceramics, and so contribute to a general picture of quotidian social practices in an Islamic town. The theoretical apparatus of the paper combines insights extracted from the works of M. B. Schiffer, well known for his contribution to the study of site formation processes, and methodological ideas by C. Orton, specialist on quantitative analysis of ceramics. These ideas have been circulated and debated by archaeologists for decades, but they have been scarcely applied to the debate on Islamic ceramics in al-Andalus. In this study they are adapted to the particular conditions of the pit assemblage in Ilbirah. The results of this analysis show that the deposit of ceramics found in the pit contains elements of two well-defined periods of early Islamic al-Andalus (late Emiral, 850–925, and Caliphal, 925–1025), and that there are at least three moments of accumulation. The earliest and latest moment of accumulation were built over a relatively long number of years, but the intermediate moment seems to correspond to a process of discarding of the elements of a single domestic unit over a period of about five to ten years. The main aim of this paper is to draw attention to the possibilities and the need of advanced quantitative research in pottery studies. It is hoped that this study will inspire similar works in other Islamic sites, so that significant comparisons can be built.
The Need for Integrated Pest Management (ipm)
Authors: Matthews G.A.
Published: December 2022

Much attention has been given to the use of chemical insecticides since the development of DDT which proved important for controlling mosquitoes and many other insect pests until Rachel Carson in her book "Silent Spring" pointed out its adverse impact on birds. More recently
greater concern has been expressed about other chemical insecticides having a detrimental impact on the natural enemies of pests, bees and moving into rivers and other areas. The EU has now promoted Integrated Pest Management as an alternative system to reduce the use of chemical pesticides.
IPM is not a new idea. In the USA, IPM was first mentioned around 1959 when in California, it was proposed that insecticides should only be applied if the number of pests exceeded an economic threshold, thus encouraging scouting to assess the number of pests in a crop. Earlier, in Central
and Southern Africa when it was decided to grow cotton, seed of a variety "Cokers Wild" was imported from USA but suffered severe damage caused by jassids. Luckily in South Africa seed had also been obtained from India and soon a variety with hairs on leaves was introduced that survived jassid
damage, although bollworms still restricted the yields. Then in 1938, it was decided that there had to be a closed season of two months in which no cotton plants should be present. This action was to reduce bollworms entering a crop as soon as fields were sown with cotton when the rain season
began in November. Bollworms, Diparopsis castanea, the red bollworm and Helicoverpa armigera, the 'American bollworm' still caused damage, so when trials began with endrin and then DDT in 1958, it was pointed out that it was important to gain more conjunction with other forms
of control. While studies using insecticides continued there were other investigations to determine the possible use of traps with pheromone to reduce bollworm damage. The immediate work was to collaborate with extension staff to train farmers how to scout for bollworm eggs and spray the insecticide
recommended for the bollworms detected in the crop.
The influence of post-amputation pain syndrome and intraosseous main vessels on the formation of limb bone stump
Authors: Bezsmertnyi Yurii , Shevchuk Viktor , Jiang Yankai
Published: December 2022

Until now, remains quit high a percentage of unsatisfactory results of amputations. At the same time, a special place is occupiedby the healing of the bone remnant — the main supporting element of the stump. Objective. To study the influence of post-amputationpain syndrome and intraosseous main vessels on the nature of reparative processes in the bone stump. Methods. Three series of 15 experimentswere conducted on 45 rabbits with amputation of the femur in the middle third and muscle plastic surgery. In the 1st and2nd series, d uring a mputation, a p erineural c atheter w as b rought to the stumps of the sciatic nerve. With its help, animals were subjectedto the following daily for 20 days: 1st series — mechanical irritation of the nerve, 20 minutes; 2nd — injection of 0.3 ml of 1 %lidocaine twice a day into the surrounding area of the nerve. Animals of the 3rd series were the control. In 1, 3, 6 months. a histologicalexamination was performed with the pouring of carcass (gelatin mixture) into the vessels. The results. In the 1st series, there was a sharpviolation of the reparative process: a change in the shape and loosening of the cortical diaphyseal plate, fractures and deformationof the stump, a significant expansion of the feeding artery and its branches with perforation of the endosteal regenerate, the absenceof formation of the bone closing plate, a violation of the microcirculation. In the animals of the 2nd series, the stumps mostly kept the shapeand structure characteristic of the diaphysis with normalization of macro- and microcirculation. In the 3rd series, the results of stumpformation were better than in the 1st, but worse than in the 2nd. Conclusions. If the pain syndrome subsides after amputation, a bonestump is formed with an organotypic shape and structure characteristic of the diaphysis, normalization of the state of bone marrowtissues and blood circulation. The rapid and complete formation of the bone closing plate contributes to the reduction of the branchesof the feeding artery and prevents the functional depressurization of the bone marrow cavity. In the presence of post-amputation painsyndrome, there are significant violations of the reparative process with the formation of an inferior bone closing plate, its penetrationby the branches of the feeding artery without the organotypic formation of the stump.
Evaluation of the CD40 receptor-ligand system in the patients with atrial fibrillation of non-valvular genesis
Authors: Ogurkova O. N. , Dragunova M. A. , Suslova T. E. , Lugacheva Yu. G. , Batalov R. E.
Published: December 2022

Thromboembolic syndrome is the most dangerous complication of atrial fibrillation which develops in about 8-15% of cases, thus presuming the role of persisting left-heart thrombosis in presence of anticoagulant therapy in some patients. When activated, the blood platelets express multiple copies of CD40L on their membrane. Hence, the soluble form of CD40 ligand is considered a marker of platelet activation and pathogenic processes associated with increased activity of the thrombotic system. Our aim was to study the content of CD40, soluble CD40 ligand and thrombomodulin in the patients with atrial fibrillation of non-valvular genesis receiving anticoagulant therapy, discerning those with a history of thrombotic complications, and the cases with atrial fibrillation, however, free of thrombotic complications. The study group included 22 healthy volunteers and 60 patients diagnosed with atrial fibrillation who received anticoagulant therapy, of whom 21 patients have developed thrombotic complications in the course of adequate anticoagulant therapy. Quantitative assays of CD40, soluble CD40 ligand and soluble thrombomodulin were performed by enzyme immunoassay using Core Facility “Medical Genomics”, Tomsk National Research Medical Center. Concentration of soluble CD40 ligand in both groups of the patients with atrial fibrillation significantly exceeded appropriate values in the group of healthy volunteers. CD40L content was increased in the group of patients with thrombotic complications against the group of patients without thrombotic complications. Thrombomodulin content in blood serum was decreased in the patients with thrombotic complications, as compared to both thrombosis-free patients, and to practically healthy volunteers. The study of CD40/CD40L system and thrombomodulin showed that the patients with thrombotic complications exhibited higher serum level of soluble CD40L, with a simultaneous decrease of thrombomodulin, a physiological anticoagulant. A comparative analysis of the CD40/sCD40L system showed increased concentrations of the biomarkers in females, when compared to males.
Pathophysiological relation between the systemic inflammation and the state of small airways in mild asthma with obesity
Authors: Yurenko A. V. , Antonyuk M. V. , Mineeva E. E. , Khodosova K. K.
Published: December 2022

The aim of present study was to establish the relationship between the level of blood serum cytokines and indexes of pulmonary function as well as to identify the markers of evolving dysfunction of small airways in obese patients with partially controlled mild bronchial asthma. We have examined 53 patients with mild asthma of partially controlled clinical course complicated with obesity (I-II degree). The control group consisted of 25 healthy volunteers. All participants underwent spirometry, bodyplethysmography. Tumor necrosis factor alpha (TNFα), interferon gamma (IFNγ), interleukins (IL) IL2, IL-4, IL-6, IL-10, IL-17A were determined in blood serum. In the patients with partially controlled mild asthma, an increase in IL-17A by 55.8%, and IL-4 by 44.9% was detected, regardless of body mass. According to the results of cluster analysis, two sub-groups were discerned, depending on the state of the small airways and the levels of pro- and anti-inflammatory cytokines. The dysfunction of small airways was shown to be accompanied by hypercytokinemia being more common in bronchial asthma with predominant Th1-and Th17-immune responses. We have revealed an association between IL-17A, IL-6 levels and functional indices reflecting the state of the small airways, as well as correlation between IFNγ and the indices of bronchial obstruction. The features of pulmonary function were found to be dependent on the cytokine status in mild asthma with obesity. Two immuno-functional variants were identified, differing in activity of systemic inflammation, type of immune response, and functional state of the small airways. The revealed relationships allow us to consider IL-17A, IL-6 and IFNγ as markers of small airways dysfunction in mild asthma of partially controlled clinical course associated with obesity.
İs Job Embeddednes Affected by Human Resources Management Practıces And Personnel Empowerment; A Research In Turkey And Iraq
Authors: SÖNMEZ Ramazan Vedat
Published: December 2022

It is important that employees contribute to the organization, work at high performance, embrace the organization's goals, and adapt so that organizations can achieve their goals, secure their existence and compete strongly. Harmony between the organization and its employees can be ensured by the employee's satisfaction with his job, his integration into the organization, his commitment to his work, his contribution to the organization's goals job embeddedness. The concept of job embeddedness, which answers the question of why employees stay in the organization, can be influenced by a number of variables. Considering the importance of continuity and harmony of health workers, who bear the brunt of the pandemic process that occurred in December 2019, in health care companies, The purpose of this study is to determine the effect of human resource management practices and personnel empowerment on job embeddedness in the health sector in two different countries, compare the results, develop proposals based on the data obtained, present new data to researchers, and contribute to the relevant literature. The research was conducted through a survey of health sector company employees in Turkey and Iraq. Analyzes of the data were made with SPSS 25.0 package program. As a result of the research: The salary and reward dimensions of human resource management have an effect on job embeddedness in companies in Turkey. In the enterprises in Iraq, data were obtained that the dimensions of education and performance evaluation were effective on job embeddedness. Another finding from the research is that personnel empowerment has an impact on job embeddedness in both countries.
Grupo de idosos como dispositivo de empoderamento em saúde: uma pesquisa-ação
Authors: Veras Danielly Cristiny de , Lacerda Gabrielle Mangueira , Forte Franklin Delano Soares
Published: December 2022

O estudo teve por objetivo construir, coletivamente, ações de promoção de saúde com idosos e profissionais de saúde e avaliar, na perspectiva dos idosos, os significados para o empoderamento em saúde. Realizou-se uma pesquisa-ação com uma equipe de Saúde da Família (eSF), núcleo ampliado de Saúde da Família e 26 idosos, em uma perspectiva dialógica e participativa. Ao final, 17 idosos foram entrevistados. Utilizou-se a técnica de análise temática. Emergiram na voz dos idosos os significados atribuídos ao grupo por meio de socialização, vínculos significativos, compartilhamento e aprendizagens. Compreende-se a potencialidade do grupo como espaço de escuta, de criação e compartilhamento de experiências e de valorização das histórias de vida dos idosos nesse território. A interação impulsionou a ressignificação do processo de envelhecimento e os projetos de vida, gerando maior satisfação com a saúde e a vida.
SENTIDO DE VIDA EM PERIÓDICOS DA EDUCAÇÃO: UMA REVISÃO DE LITERATURA INTEGRATIVA
Authors: Belo Rafael Alexandre , Alves Maria Dolores Fortes
Published: December 2022

A concepção de sentido de vida, e suas derivações, possuem um potencial interdisciplinar e transdisciplinar. Este artigo apresenta uma Revisão de Literatura Integrativa acerca desta concepção em periódicos da área da Educação, a partir do banco de dados do Portal de Periódicos da Capes. Tomou-se como questão norteadora o seguinte enunciado: Como a concepção de sentido de vida está situada nos artigos de periódicos da área da Educação? Os resultados mostram que a noção de sentido de vida é trabalhada pelas pesquisas em variadas perspectivas, diferenciando de um nível mais situacional a outro mais global, ou entre um caráter mais motivacional a outro mais cognitivo e centrado no significado, ou em relação à abordagem metodológica, ou à abordagem explicativa. O levantamento mostrou que a concepção de sentido de vida tem sido utilizado em produções de periódicos da área de Educação de diversos países. Por outro lado, a quantidade de artigos que trabalharam com essa concepção, nos últimos cinco anos, dentro do seu processo investigativo, mostra-se pequena, dado a capacidade de problematização que se relaciona a tal concepção.
KOVİD-19 PANDEMİSİNE BAĞLI KARANTİNA DÖNEMİNDE MEME KANSERİ HASTALARINDA PATOLOJİK VE KLİNİK ÖZELLİKLER
Authors: EREN KUPIK Gülnihan , ALTUNDAĞ Kadri
Published: December 2022

Amaç: Çalışmamızda 11 Mart 2020 ile 30 Mayıs 2020 (Karantina) ve 11 Mart 2019 ile 30 Mayıs 2019 (Karantina öncesi) arasında tanı alan meme kanseri hastalarını klinik ve patolojik özellikler açısından karşılaştırmayı amaçladık.

Materyal ve metod: 23'ü karantina döneminde ve 47'si karantina öncesi dönemde olmak üzere toplam 70 hasta retrospektif olarak değerlendirildi. Menopoz durumu, semptom varlığı, ameliyatın türü, hormonal alt gruplar, kemoterapinin amacı, T, N, M evreleri çapraz tablolar kullanılarak gruplara ayrıldı. Gruplar arasındaki farklılıklar Ki-kare testleri kullanılarak karşılaştırıldı.

Bulgular: Çalışmamızda, karantina döneminde hasta sayısı karantina öncesi döneme göre daha azdı. Karantina dönemindeki ve karantina öncesi dönemdeki yaş, menopoz durumu, tedaviye başlama zamanı, tarama oranı, hormonal alt tip, ameliyat tipi, T, N, M evresi gibi değişkenlerde anlamlı bir fark bulunmadı.

Sonuç: Karantina döneminde hasta sayısı karantina öncesi döneme göre daha azdı. Meme kanseri hastalarında karantina süresi ile aynı dönemden bir yıl önceki zaman aralığı arasında klinik bir fark saptanmadı.