bluuebunny/crossref_metadata_2025 huggingface dataset:
A Magyarországra érkező külföldiek turizmusbiztonsággal kapcsolatos percepciói
Authors: Tokodi Panna
Published: July 2022

Jelen tanulmány célja, hogy feltárja a Magyarországra látogató külföldi turisták biztonságérzetének dimenzióit, illetve azonosítsa a desztináció-választásukban és a biztonsággal összefüggő attitűdjükben szerepet játszó főbb tényezőket, különös tekintettel az utazás során felmerülő kockázatokra. Tekintettel arra, hogy a turizmus Magyarország gazdasági és társadalmi életében prioritást élvez, a külföldi turisták biztonságával kapcsolatos vizsgálat eredményeinek publikálása elősegíti az ágazat települési, térségi és országos szintű fejlesztését. Az 1000 főre kiterjedő kérdőíves adatfelvétel 2019 második felében, a koronavírus-világjárvány megjelenését megelőzően készült, így a vizsgálat eredményei a pandémia turizmusbiztonságra gyakorolt hatásainak értékelésére nem alkalmasak. Ugyanakkor mind a turisztikai ágazatban, mind a rendvédelem területén dolgozók számára hasznos segítséget nyújt a legérzékenyebb biztonsági területek és kockázati tényezők mélyebb feltárásához.
In-situ measurements of wall moisture in a historic building in response to the installation of an impermeable floor
Authors: Briggs Kevin , Ball Richard , McCaig Iain
Published: July 2022

When impermeable ground bearing slabs are installed in old buildings without a damp-proof course, it is a common belief of conservation practitioners that ground moisture will be ‘driven’ up adjacent walls by capillary action. However, there is limited evidence to test this hypothesis.

An experiment was used to determine if the installation of a vapour-proof barrier above a flagstone floor in a historic building would increase moisture content levels in an adjacent stone rubble wall. This was achieved by undertaking measurements of wall, soil and atmospheric moisture content over a three-year period. Measurements taken using timber dowels showed that the moisture content within the wall did not vary in response to wall evaporation rates and did not increase following the installation of a vapour-proof barrier above the floor. This indicates that the moisture levels in the rubble wall were not influenced by changes in the vapour-permeability of the floor.
AUTOMEDICAÇÃO E SEUS RISCOS À SAÚDE DURANTE A PANDEMIA DA COVID-19: REVISÃO INTEGRATIVA
Authors: Alencar Gustavo de Oliveira , Alencar Jean Pierre de Oliveira , Paiva Larissa Varela de , Mori Edna , Mendes Rafael de Carvalho
Published: July 2022

Automedicação é o ato de ingerir medicamentos, sem qualquer orientação do profissional adequado. Durante a pandemia da COVID-19 ocorreram muitos casos relacionados à hidroxicloroquina, cloroquina, azitromicina, ivermectina, nitazoxanida, além de polivitamínicos contendo zinco, vitamina C e D. O objetivo deste trabalho foi realizar uma revisão sobre a automedicação e os riscos à saúde durante a pandemia da COVID-19. Tratou-se de uma revisão integrativa de caráter qualitativo, pesquisando trabalhos científicos relacionados à automedicação e a COVID. As bases de dados utilizadas foram: LILACS (Literatura Científica e Técnica da América Latina e Caribe), MEDLINE (Medical Literature Analysis and Retrieval System Online) e SciELO (Scientific Electronic Library Online). Os descritores aplicados foram: Automedicação/COVID e Self-medication/COVID. Dos 558 artigos, publicados entre 2019 a 2021, disponíveis na íntegra gratuitamente, no idioma português e inglês, 9 foram selecionados, conforme o protocolo de pesquisa. Os estudos abordaram a prática da automedicação no período da pandemia para medidas preventivas. Dentre as classes farmacêuticas abordadas no estudo foram: antimaláricos, antirretrovirais, antibacterianos, vitaminas, analgésicos e antipiréticos. Campanhas educativas são necessárias, uma vez que o uso inadequado pode gerar resistência bacteriana, intoxicações por superdosagem, efeitos colaterais e até mesmo piora do quadro de alguma doença já existente.
Notes from the Editors, July-August 2022
Authors: The Editors -
Published: July 2022

buy this issue

Between 1949 and 1980, over a hundred articles in Monthly Review dealt with the Soviet Union directly, with many more addressing it indirectly. But, after 1993, treatments of post-Soviet Russia in the magazine largely ceased.
The Limits to Growth: Ecosocialism or Barbarism
Authors: Espinosa Alberto Garzón
Published: July 2022

A major deficiency of the growth-obsessed model driving global neoliberal economic policy is its lack of understanding on the Earth System on which it—and indeed, all life on Earth—relies.
Surviving Through Community Building in Catastrophic Times
Authors: Tsui Sit , Chi Lau Kin
Published: July 2022

Over the last twenty years, China has gained recognition for its efforts to reduce pollution and remediate the effects of industrialization within its borders. To mitigate the adverse effects of this reality, communities are returning to grassroots projects that present an alternative to unchecked globalization.
Measures to Defend Life on Planet Earth and Improve Living Conditions
Authors: Brazilian popular movements -
Published: July 2022

Out of the dissatisfaction with the 2021 UN Climate Change Conference in Glasgow, Brazilian popular movements came together to propose measures to defend life on Earth.
Surviving Collapse Through Social Transformation and Regeneration
Authors: Ergas Christina
Published: July 2022

As the effects of the climate crisis become ever-more deeply felt worldwide, our vision of the future must be grounded in radical imaginaries of the world to come, based on the experiences of those who suffer most under the current system of exploitation and violence.
Topiramate in an Experimental Model of Epilepsy - Similarity between Generic, Similar and Reference Drugs
Authors: Malveira George Linard Silva , Santos Sacha Aubrey Alves Rodrigues , Leite Gerlânia de Oliveira , Meneses Gdayllon Cavalcante , Campos Adriana Rolim
Published: July 2022

Background and Purpose: The literature is still controversial in relation to therapeutic differences between innovative, generic, and similar anti-seizures medications (ASM). Topiramate (TPM) is an ASM used in the treatment of various seizure types and in different epileptic syndromes, as well as in other groups of morbidities, and it is available in many generic and similar forms, besides the innovator. The aim of this translational work was to compare different brands of TPM by using animal models of seizures induced by pentylenetetrazole (PTZ).Methods: Five brands of TPM (one reference, two similar and two generics) were tested in mice. Animals were previously treated with TPM (n=6/brand) and latencies from PTZ injection to onset of manifestations, first seizure and death were measured and compared between groups. Experiment was conducted in two settings: acute seizure model (PTZ 80 mg/kg) and kindling model (PTZ 20, 30, and 40 mg/kg in 8 alternate days).Results: The experiment did not demonstrate significant differences between the TPM brands regarding the protective effect in the acute seizure and kindling models.Conclusions: In conclusion, results can be explained by true therapeutic equivalence or insufficiency of the PTZ model to reveal differences among brands.
Global Warming and Border Carbon Adjustments
Authors: Hong Sungwan , Sim Seung-Gyu , Obashi Ayako , Tsuruta Yoshitaka
Published: July 2022

This study examines the welfare implications of allowing border carbon adjustments (BCAs) in a globalized economy characterized by international trade and cross-border pollution (CBP). The model predicts that adopting BCAs is a weakly dominant strategy and global welfare is maximized when at least one country adopts BCAs in the presence of CBP, such as global warming. This is because adopting BCAs induces other countries to raise their domestic emission tax rates without concerns such as the excessive shrinkage of domestic production and aggravation of CBP.
Automatic landmark identification for surgical 3d-navigation – A proposed method for marker-free dental surgical navigation systems
Authors: Bischofberger Micha , Böhringer Stephan , Schkommodau Erik
Published: July 2022

This paper proposes a conceptual method to calculate the pose of a stereo-vision camera relative to an artificial mandible without additional markers. The general method for marker-free navigation has four steps: 1) parallel image acquisition by a stereo-vision camera, 2) automatic identification of 2d point pairs (landmark pairs) in a left and a right image, 3) calculation of related 3d points in the joint camera coordinate system and 4) matching of 3d points generated to a preoperative 3d model (i.e., CT data based). To identify and compare landmarks in the acquired stereo images, well-known algorithms for landmark detection, description and matching were compared within the developed approach. Finally, the BRISK algorithm (Leutenegger S, Chli M, Siegwart RY. BRISK: Binary Robust invariant scalable keypoints. Proceedings of the IEEE International Conference on Computer Vision; 2011: 2548–2555) was used. The proposed method was implemented in MATLAB® and validated in vitro with one artificial mandible. The accuracy evaluation of the camera positions calculated resulted in an average deviation error of 1.45 mm ± 0.76 mm to the real camera displacement. This value was calculated using only stereo images with over 100 reconstructed landmark pairs each. This provides the basis for marker-free navigation.
Serum free light chain analysis: persisting limitations with new kids on the block
Authors: Van Hoovels Lieve , Vercammen Martine , Nevejan Louis , Cornette Margot , Briers Pieter-Jan , Deeren Dries , Van Droogenbroeck Jan , Fostier Karel , De Smet Dieter
Published: July 2022

Objectives

Serum free light chain (sFLC) measurements have inherent analytical limitations impacting sFLC clinical interpretation. We evaluated analytical and diagnostic performance of three polyclonal sFLC assays on four analytical platforms.

Methods

sFLC concentration was measured using Diazyme FLC assays (Diazyme) on cobas c501/c503 analyzer (Roche); Freelite assays (The Binding Site) on Optilite analyzer (The Binding Site) and cobas c501 analyzer and Sebia FLC ELISA assays (Sebia) on AP22 ELITE analyzer (DAS). Imprecision, linearity, method comparison vs. Freelite/Optilite, antigen excess detection and reference value verification were assessed. Diagnostic performance was compared on 120 serum samples and on follow-up samples of five patients with κ and λ monoclonal gammopathy.

Results

Method comparison showed excellent correlation with Freelite/Optilite method for all assays. A large proportional negative bias was shown for both Sebia κ and λ ELISA and a significant positive proportional bias for λ in the low (<10 mg/L) Freelite/cobas c501 method. Clinically relevant underestimation of κ sFLC levels due to antigen excess was shown for 7% of each Diazyme/cobas application and for 11 and 32.1% of λ sFLC assay of respectively Diazyme/cobas and Sebia/AP22. sFLC reference values revealed application specific. Cohen’s κ values were (very) good for κ sFLC but only moderate to good for λ sFLC. In 4/10 follow-up patients, significant differences in clinical interpretation between sFLC assays were noticed.

Conclusions

Important analytical limitations remain for all sFLC applications. Differences in reference values and diagnostic performance hamper interchangeability of sFLC assays. Assay specific sFLC decision guidelines are warranted.
A Late Etruscan Burial at Podere Cannicci (Civitella Paganico – Grosseto)
Authors: Sebastiani Alessandro
Published: July 2022

In March 2021, following some agricultural activities on a slight relief in the area of Civitella Paganico, the remains of a second century B.C.E. burial were excavated by the research team of the IMPERO Project (Interconnected Mobility of People and Economies along the River Ombrone). This paper details the results of the rescue excavations and presents the preliminary data on the nearby settlement of Podere Cannicci to contextualize its necropolis. Finally, the paper addresses some initial thoughts on the broader importance of the discovery in terms of settlement networks and spheres of cultural influences in this liminal area.
Influence of heterogeneity on fluid property variations in carbonate reservoirs with multistage hydrocarbon accumulation: A case study of the Khasib formation, Cretaceous, AB oilfield, southern Iraq
Authors: Wang Qiang , Wen Tao , Li Hongxi , Zeng Xinyao , Wang Xingzhi , Xin Jun , Sun Li , Wang Chunpu , Zhou Yuezong
Published: July 2022

The fluid distribution is considerably influenced by the reservoir homogeneity. This study analyzes carbonate reservoir heterogeneity and hydrocarbon accumulation processes in the Khasib reservoirs in AB oilfield in the Middle East to discuss factors controlling the distribution of fluid and the effects of this distribution on the productivity of single wells. The Khasib reservoirs in the AB oilfield show uniform vertical distributions, with a large difference in the longitudinal pore throats, and the upper part of the reservoir is better than the lower one. Because the hydrocarbon accumulation is multiphasic, the heterogeneity of crude oil is based on whether traps are formed in the early or late stage of source rock formation during accumulation. Moreover, the longitudinal physical differences in crude oil properties are mainly attributed to the longitudinal differences in the pore throats. The difference in the pore throat and physical properties of crude oil affords differences in the productivity of horizontal wells in different subzones.
Early origins of respiratory disease
Authors: Greenough Anne , Milner Anthony David
Published: July 2022

Chronic respiratory morbidity is unfortunately common in childhood, particularly in those born very prematurely or with congenital anomalies affecting pulmonary development and those with sickle cell disease. Our research group, therefore, has focused on the early origins of chronic respiratory disease. This has included assessing antenatal diagnostic techniques and potentially therapeutic interventions in infants with congenital diaphragmatic hernia. Undertaking physiological studies, we have increased the understanding of the premature baby’s response to resuscitation and evaluated interventions in the delivery suite. Mechanical ventilation modes have been optimised and randomised controlled trials (RCTs) with short- and long-term outcomes undertaken. Our studies highlighted respiratory syncytial virus lower respiratory tract infections (LRTIs) and other respiratory viral LRTIs had an adverse impact on respiratory outcomes of prematurely born infants, who we demonstrated have a functional and genetic predisposition to respiratory viral LRTIs. We have described the long-term respiratory outcomes for children with sickle cell disease and importantly identified influencing factors. In conclusion, it is essential to undertake long term follow up of infants at high risk of chronic respiratory morbidity if effective preventative strategies are to be developed.
Diagnostic value of long noncoding RNA LINC01060 in gastric cancer
Authors: Huang Junhui , Wu Junrong , Hu Zuojian , Mo Cuiju , Chen Huaping , Lu Liuyi , Chen Mingxing , Huang Xiamei , Qin Xue
Published: July 2022

Objectives

Gastric cancer (GC) is a common gastrointestinal tumor that threatens human health. The sensitivity and specificity of traditional tumor markers do not meet the requirements for detection of GC. Long noncoding RNAs (lncRNAs) are crucial for the development of tumors. Hence, in this study, LINC01060 will be evaluated for its diagnostic value in GC.

Methods

Quantitative real-time PCR (qRT-PCR) was used to determine the relative expression levels of LINC01060 in GC tissues and blood samples. In addition, the relationship between the expression levels of LINC01060 and the clinicopathological features of the patients was analyzed. Receiver operating characteristic (ROC) curves were utilized to assess the diagnostic efficacy of LINC01060, carcinoembryonic antigen (CEA), and carbohydrate antigen 19-9 (CA19-9) in GC.

Results

The expression of LINC01060 was found to have decreased in GC tissues (p<0.01). Notably, compared with peptic ulcers and healthy controls, the expression levels of LINC01060 in the whole blood of GC patients was found to have decreased. Furthermore, LINC01060 exhibited higher sensitivity and specificity than CEA and CA19-9 in differentiating GC from healthy controls (AUC=0.872, sensitivity=96.0%, specificity=76.7%). With regard to traditional biomarkers, the AUC of CEA and CA19-9 were 0.715 (sensitivity=86.0%, specificity=50.0%) and 0.634 (sensitivity=63.0%, specificity=76.0%), respectively. Remarkably, the other gastrointestinal tumors did not show any statistically significant differences. The presence of LINC01060 was not found to be significantly associated with characteristic clinicopathological factors.

Conclusions

LINC01060 might be useful as a biomarker for diagnosing GC and distinguishing GC patients from healthy controls.
Crystal structure of catena-poly[(μ
2-4,4′-bipyridine-κ2
N:N′)-bis(4-bromobenzoato-κ1
O)zinc(II)], C24H16Br2N2O4Zn
Authors: Yang Xiuyan , Luo Yingchun
Published: July 2022

C24H16Br2N2O4Zn, monoclinic, I2/a (no. 15), a = 7.4191(9) Å, b = 24.458(3) Å, c = 25.810(3) Å, β = 92.426(3)°, V = 4679.2(10) Å3, Z = 8, R

gt
(F) = 0.0514, wR

ref
(F
2) = 0.1710, T = 296(2) K.
On theoretical analysis of nonlinear fractional order partial Benney equations under nonsingular kernel
Authors: Shah Kamal , Seadawy Aly R. , Mahmoud Anhar B.
Published: July 2022

In the present article, the first step is devoted to develop some results about existence and uniqueness of solution to a general problem of fractional order partial differential equations (FPDEs) via classical fixed point theory. In the second step, a novel technique is used to handle the semi-analytical approximate solution for the considered general problem. Then, we extend the said result to fractional order partial Benney equations (FOPBEs) of the second and third order, which are special cases of the general problem we considered. We study the proposed problem under the Caputo-Febrizo fractional derivative (CFFD). With the help of the proposed method, we derive a series type approximate (semi-analytical) solution. Some numerical interpretations and visualizations are also given.
Polypropylene pyrolysis kinetics under isothermal and non-isothermal conditions: a comparative analysis
Authors: Nisar Jan , Khan Muhammad A. , Ali Ghulam , Iqbal Munawar , Din Muhammad Imran , Hussain Zaib , Bhatti Ijaz A. , Al-Kadhi Nada S. , Alamro Fowzia S.
Published: July 2022

The kinetics of polypropylene pyrolysis has been studied under isothermal and non-isothermal conditions using Arrhenius and Kissinger–Akahira–Sunose (KAS) equations. Under isothermal conditions, applying first order kinetic model, activation energy (Ea) and pre-exponential factor (A) were investigated and observed as 119.7 kJ mol−1 and 1.2 × 1010 min−1, while in case of non-isothermal kinetics using Kissinger–Akahira–Sunose method, the average Ea and A were found to be 91.23 kJ mol−1 and 2.3 × 107 min−1, respectively. A comparison among the isothermal and non-isothermal reactions was made on the basis of kinetics parameters. The results from both the methods showed trivial variation in kinetic parameters of the pyrolysis reaction which may be due to two major reasons. Firstly, the selection of the kinetic model applied and secondly the inconsistency due to various experimental conditions used which can be reduced at optimized conditions. As the disposal of plastic materials need reliable kinetics information to model their decomposition reactions, therefore, the kinetics data thus obtained from pyrolysis reaction of model polypropylene will help in the utilization of polypropylene waste as energy source on industrial scale.
Digital FPGA-based processing of pulses of gas-filled gamma-radiation detector for acoustic noise suppression
Authors:   National Science Center ‟Kharkov Institute of Physics and Technology”, Pudov A. O. , Sokolov S. A. , Abyzov A. S. , Rybka A. V. , Kutny V. E.
Published: July 2022

Gas-filled proportional detectors of ionizing radiation often contain such elements as thin anode wire, which make them sensitive to external acoustic or vibrational impact. This study investigates such sensitivity for the case of the proportional -radiation detectors filled with high-purity xenon gas. The detector demonstrates a dependence of its signal noise on the external acoustic wave frequency, the character of which most likely depends on the design of the detector, i.e. on such parameters as diameter and tension strength of the anode wire, etc. To suppress the negative impact of acoustic noise on the characteristics of the detector, the detector digital signal is processed in a Field-Programmable Gate Array board. The authors investigate the algorithm of «time windows», which allows separating (filtering) low-frequency noise in the output signal of a gas-filled detector, which arises due to the influence of external sound, from the useful signal, i.e. the ionization pulses. This approach allows performing spectral measurements of -radiation with a significant acoustic noise background, when detectors with a conventional analog spectrometric channel cannot handle the task.
Ultrasensitive Quantification of Multiple Estrogens in Songbird Blood and Microdissected Brain by LC-MS/MS
Authors: Jalabert Cecilia , Shock Maria A. , Ma Chunqi , Bootsma Taylor J. , Liu Megan Q. , Soma Kiran K.
Published: July 2022

Neuroestrogens are synthesized within the brain and regulate social behavior, learning and memory, and cognition. In song sparrows,Melospiza melodia, 17β-estradiol (17β-E2) promotes aggressive behavior, including during the nonbreeding season when circulating steroid levels are low. Estrogens are challenging to measure because they are present at very low levels, and current techniques often lack the sensitivity required. Furthermore, current methods often focus on 17β-E2and disregard other estrogens. Here, we developed and validated a method to measure four estrogens [estrone (E1), 17β-E2, 17α-estradiol (17α-E2), estriol (E3)] simultaneously in microdissected songbird brain, with high specificity, sensitivity, accuracy, and precision. We used liquid chromatography tandem mass spectrometry (LC-MS/MS), and to improve sensitivity, we derivatized estrogens using 1,2-dimethylimidazole-5-sulfonyl-chloride (DMIS). The straightforward protocol improved sensitivity by 10-fold for some analytes. There is substantial regional variation in neuroestrogen levels in brain areas that regulate social behavior in male song sparrows. For example, the auditory area NCM, which has high aromatase levels, has the highest E1and 17β-E2levels. In contrast, estrogen levels in blood are very low. Estrogen levels in both brain and circulation are lower in the nonbreeding season than in the breeding season. This technique will be useful for estrogen measurement in songbirds and potentially other animal models.
Oxi-P GUI: A Graphical User Interface (GUI) for wastewater treatment process in oxidation pond
Authors: MOHD FAUZI SYAFIQAH HANIS , Mohd Jamil Norazaliza
Published: July 2022

The wastewater treatment process is aimed to reduce pollution to the appropriate level. An oxidation pond system can treat contaminants in wastewater. Oxidation ponds are use sunlight, bacteria, and algae to treat wastewater. This study developed an improved mathematical model and a graphical user interface (GUI), called oxi-P GUI to predict the wastewater treatment process in an oxidation pond. The correlation between dissolved oxygen (DO), chemical oxygen demand (COD), coliform bacteria, as well as concentrations of phototrophic bacteria (PSB) were examined. In MATLAB software, a revised model consisting of ordinary differential equations (ODEs) set of integrating the Monod equation was numerically solved utilising the fourth order Runge-Kutta method. The current model's root mean square error (RMSE) values were compared to the suggested model's RMSE values for model validation. The model offered a more accurate estimate than the existing model of changes in the amount of concentration in oxidation pond, which was necessary to produce acceptable water quality. A wastewater management personnel may use GUI to track water quality and determine the most effective wastewater treatment mechanism. Additionally, this user-friendly GUI will give a better understanding about the treatment process, especially to people with less programming skills.
Management of cranial diabetes insipidus: clinical outcomes and patient perception of care
Authors: Dilrukshi M D S A , Vickars Marcus , May Christine J H , Makaya Taffy , Ryan Fiona , Jafar-Mohammadi Bahram , Wass John A H , Pal Aparna , Garrahy Aoife
Published: July 2022

Objective

There is growing recognition of morbidity and mortality that can occur in patients with cranial diabetes insipidus (CDI) during hospitalisation, due to prescribing errors and dysnatraemia, often related to confusion between CDI and diabetes mellitus among non-specialists. We aimed to investigate this.

Methods

Data for each hospitalisation in patients with CDI attending Oxford University Hospital (OUH) were collected retrospectively. The same cohort were invited to complete a questionnaire by telephone.

Results

One hundred and nine patients were included, median age was 42 (range: 6–80) years. Route of desmopressin was tablet, melt and nasal spray in 74%, 7% and 17% of patients, respectively, while two patients used a combination of tablet and nasal spray. There were 85 admissions to OUH by 38 patients between 2012 and 2021. Daily measurement of serum sodium was performed in 39% of admissions; hyponatraemia and hypernatraemia occurred in 44 and 15% of admissions, respectively. Endocrine consultation was sought in 63% of admissions post-2018. Forty-five of 78 patients (58%) self-reported ≥1 admission to any hospital since diagnosis. Of these, 53% felt their medical team did not have a good understanding of the management of CDI during hospital admission. Twenty-four per cent reported delay in administration of desmopressin, while 44% reported confusion between CDI and diabetes mellitus, often leading to unnecessary blood glucose monitoring.

Conclusion

Dysnatraemia is common in hospitalised patients with CDI. More than half of patients perceived their medical team’s understanding of CDI to be poor when admitted with intercurrent illness. A coordinated approach, including early consultation of specialists, frequent serum sodium monitoring, and education of hospital specialists is needed to address this.
Pasirengimas pensijai: psichologiniai veiksniai ikipensiniame amžiuje ir sąsajos su psichologine gerove pensijoje
Authors:   , Sadauskaitė Raimonda
Published: July 2022

Preparing for retirement: Psychological factors in the pre-retirement age and links with the psychological well-being during retirement
MYTHOLOGICAL HERITAGE OF SCANDINAVIAN LEXEMES IN O. SCOTT’S FANTASY NOVEL TWILIGHT OF THE GODS
Authors: Sharapenkova Natalia , BAKHLAEVA Marina
Published: July 2022

The current fantasy genre is inspired by the folklore and mythological tradition whose heritage is investigated in the article using the example of Scandinavian lexemes. The subject for research is a fantasy novel Twilight of the Gods by O. Scott. It describes the events taking place in Sweden at the beginning of the 13th century, when the crusade of Conrad the White was going to eradicate paganism. A large number of Scandinavian lexemes are used in the novel: they are given in italics with all the diacritical marks and special letters that were traditionally found in the Old Norse language: ð, á, ú, é, æ, ó. In total, there are 30 different lexemes in the novel, but the article turns to the most frequent ones. Based on the results of the work, it is concluded that the use of traditional words not only diversified the text of the novel Twilight of the Gods adding some folklore colors to it, but also showed the beauty of the northern European languages.
LEXEMES WITH THE -VOD- ROOT IN THE RUSSIAN DIALECTS OF THE KARELIAN POMORIE
Authors: Guseva Elena , Sidorova Polina
Published: July 2022

The article uses the material of differential dictionaries to investigate the lexemes with the -vod- root and their variants functioning in the Karelian Pomorie. It analyzes the semantics, part-of-speech affiliation, areal distribution, and etymology of these formations, and provides some ethnolinguistic and folklore details. The study revealed nouns found mostly only in the Pomorie, which denote water and water-related objects of inanimate nature and household items, naming people and mythological characters. The lexemes included in nine lexico-semantic groups were formed mainly by adding suffixes. Their accentological, phonemic, morphological, and word-forming variants have also been found. The research revealed some individual rare adjectives and no adverbs, words describing the category of state or verbs.
Microbial Culture Characteristics and Antimicrobial Susceptibility Patterns Associated with Vesicovaginal Fistula
Authors: Firdaus Gugum Indra , Tjahjodjati Tjahjodjati
Published: July 2022

Vesicovaginal fistula (VVF) is commonly linked with recurrent urinary tract infection (UTI). Thus, the patterns of the pathogenic microorganism becomes important consideration in the management of this disease. This study aimed to describe patient profiles, disease etiology, and antimicrobial susceptibility patterns of microorganisms in VVF patients. This retrospective study was conducted on 49 medical records of vesicovaginal fistula patients seen from January 2016 to December 2020. The most prevalent age group of the patients was 40-50 years old. Analysis demonstrated that the leading etiology for VVF among these patients was malignancy (73.47%). The antimicrobial susceptibility was tested using the disc diffusion method and Escherichia coli (44.90%) and Proteus mirabilis (14.29%) were identified as the bacterial pathogens most frequently isolated from urine samples. Of the 39 patients with significant growth of organism cases, 29 (74.35%) had symptomatic UTIs. The isolated gram-negative bacteria had excellent sensitivity to aztreonam, ertapenem, and meropenem, with a more than 90% susceptibility rate, while the gram-positive bacteria had good sensitivity to amikacin, cefepime, tigecycline, aztreonam, ertapenem, and meropenem, with a more than 90% susceptibility. In conclusion, bacterial culture and antibiotic susceptibility test (AST) remains an essential part of managing VVF and their results can be used as a reference for empirical therapy. Amikacin, cefepime, tigecycline, aztreonam, ertapenem, and meropenem should be considered for treatment of UTIs associated with VVF.
A Ten-Year Study on Risk Factors of Orchiectomy in Testicular Torsion
Authors: Rulianov  , Adi Kuncoro , Safriadi Ferry
Published: July 2022

Testicular torsion is a common urological emergency among children, peaking in neonates and pubertal age with an incidence rate of 3.8 in 100.000 (0.004%) annually. This study aimed to explore the characteristics of testicular torsion cases and risk factors for orchiectomy in testicular torsion patients. This was a retrospective study on medical records of patients diagnosed with testicular torsion underwent surgery at the urology department of Dr. Hasan Sadikin General Hospital Bandung, Indonesia, from January 2009 to August 2019. Patient characteristics including age, duration of symptom, location, etiology, and degree of torsion were analyzed. A total of 86 cases of testicular torsion were identified, with most cases (54 cases, 62.8%) occured at the mean age 14.67 ± 2.4 years old. Most patients (69 patients, 80.2 %) arrived more than six hours after the onset, and 65 (75.5%) and 4 (4.6%) of them underwent orchiectomy and orchidopexy, respectively. The remaining patients (17 patients, 19.8%) came less than 6 hours after the onset and only 8 (9.3%) and 9 (10.4%) underwent orchiectomy and orchidopexy, respectively. Both duration of torsion (p = 0.000, P<0.05) and degree of torsion (p = 0.006 , P<0.05) were significantly correlated with orchiectomy. In conclusion, the risk factor for orchiectomy is strongly related to duration and degree of torsion. The chance for testis salvation increases if torsion happens before 4.5 hours and the degree of torsion is below 180 degrees. Prompt diagnosis and treatment is the only key to testicular salvation.
Role of P27kip1 Protein, P45skp2Coactivator, and P38jab1 Coactivator In Preventing Rhabdomyosarcoma (RMS) in Oral Cavity of Children
Authors: Sasmita Inne Suherna , Indriyanti Ratna , Soewondo Willyanti
Published: July 2022

Rhabdomyosarcoma is a rare malignant tumor that attacks the differentiation of skeletal muscle and usually affects children, contributing to about 60% of all soft tissue sarcomas. The purpose of this study was to examine the relationship between p27Kip1 immunoexpression and p45Skp2 and p38Jab1 coactivators, as well as the relationship between p27Kip1 immunoexpression and p45Skp2 and p38Jab1 coactivators on stages and prognosis of oral RMS in children. This was a restrospective study on the immunoexpression of p27Kip1 and p45Skp2 and p38Jab1 coactivators on RMS cells. The RMS stage was determined according to the American Joint Committee of Cancer/AJCC of stages 1–4, and were divided into group I (stages 1 and 2) and group II (3 and 4). Samples were retrieved fromt he paraffin blocks of patients with embryonal RMS. Each paraffin block was cut, and 6 samples with 5 µm thickness from each block were examined using p27Kip1, p45Skp2, and p38Jab1 proteins. The analysis was performed using a linear regression test on the relationship between p27Kip1 and p45Skp2 and p38Jab1, resulting in a p-value of 0.000 (<0.05) and a coefficient value of b -1.36. Meanwhile, the stage was analyzed using the Wald test of 8.0688, resulting in a p-value of 0.0045 with a significant negative correlation. Analysis on the relationship between p45Skp2 and p38Jab1 and the RMS stage was performed using the Gamma test, resulting in a significant positive correlation (p<0.05).
Oral Ulcer Healing Activity of Lemon Pepper Ethanol Extract Gel in Streptozotocin-Induced Diabetic Wistar Rats
Authors: Chiuman Veranyca , Chiuman Linda , Tanjung Dian Soraya , Miftahulaila Mourent , Erawati Suci , Florenly
Published: July 2022

Diabetes mellitus (DM) is a metabolic condition where the body's ability to produce and utilize insulin is impaired; thus, wound healing process is slower than usual in patients with DM. Lemon pepper has both antioxidant and anti-inflammatory properties. This study aimed to investigate the effect of topical application of lemon pepper fruit ethanol extracts on the healing process of oral traumatic ulcers in diabetic rats. This study was performed at the Pharmacology Laboratory, Faculty of Medicine, Universitas Prima Indonesia from September 2021–October 2021. Thirty males diabetic Wistar rats were thermally injured on the lower labial mucosa and divided into five groups: control, standard, and lemon pepper gel 5%, 7.5%, and 10% groups. The ulcer size was measured after injury and on the 7th and 14th day. On the last day, all rats underwent both routine blood count and histology study for oral ulcer tissue. On the 14th day, all treatment groups showed some significant difference wound contraction, with the highest tendency of wound contraction seen in both lemon pepper gel 10% and standard groups (62.50%. p-value =0.001). The improvement of wound contraction was also supported by reduced white blood cell count (p-value<0.05) in routine blood count and regeneration of epidermis and dermis tissues in the histology study. Hence, it can be concluded that the lemon pepper extract gel in all concentrations has good physical stability and the lemon pepper gel with the highest concentration group presents the best ulcer healing activity compared to other concentrations and has similar ulcer healing activity as the standard group that receives Kenalog® in Orabase.
ОЦІНЮВАННЯ СОЦІАЛЬНОЇ ВРАЗЛИВОСТІ: ТЕОРЕТИКО-МЕТОДОЛОГІЧНІ АСПЕКТИ
Authors: РИНДЗАК Ольга
Published: July 2022

Розробка ефективних стратегій і прийняття оперативних рішень у системі управління надзвичайними ситуаціями повинні ґрунтуватися на комплексному оцінюванні вразливості соціальних систем. Для цього слід розвивати його теоретико-методологічні основи в напрямі забезпечення його комплексності. Сформульовано авторське визначення вразливості як властивості соціальної системи, що характеризується мірою схильності, чутливості до шкідливого впливу небезпечних подій і водночас ступенем здатності справлятися з ними, чинити опір і відновлюватися після них. Проаналізовано такі основні фактори вразливості, як диспозиція, схильність зазнати впливу лиха, катастрофи (exposure); чутливість (susceptibility) і резилетність (resilience). Висвітлено чотири компоненти соціальної вразливості (економічну, соціальну, екологічну, фізичну) та головні індикатори їх оцінювання.
Показано, що економічна вразливість характеризує потенційний вплив небезпек на економічні процеси, майно чи певні сектори економіки; соціальна – стосується окремих груп населення, які не здатні самостійно впоратися з катастрофами, їх зв’язку, характеру відносин із суспільством; екологічна – включає індикатори, що характеризують вплив небезпечних подій на природне середовище (флору, фауну, екосистеми, біорізноманіття); фізична – визначає можливість, потенціал певного елемента чи системи зазнати змін або пошкоджень під впливом природних чи антропогенних небезпек. Запропоновано аналіз ментальної вразливості, яка включає не лише установки окремих індивідів чи груп стосовно навколишнього світу, зокрема небезпек і загроз, а й загальний спосіб мислення, певні знання і навички подолання проблем.
Розроблено логіко-структурну схему дослідження соціальної вразливості, що дозволяє здійснити комплексний підбір індикаторів для кожної її компоненти (економічної, соціальної, екологічної, фізичної та ментальної) крізь призму факторів диспозиції, чутливості й резилентності. Комплексне оцінювання соціальної вразливості є передумовою для розробки заходів з її зменшення, що здатне запобігти людським, фізичним і економічним втратам.
Morphogenesis of fruit as a subject matter for the carpological studies
Authors:   Ivan Franko National University of Lviv, Ukraine, Odintsova A.V.
Published: July 2022

In this review, the concept of fruit morphogenesis is treated in the context of implementation of the evo-devo approach in carpology. A new viewpoint on the fruit morphogenesis is proposed and justified, comprising the pre-anthetic, as well as post-anthetic periods of fruit development, id est, development of the gynoecium, and development of the fruit itself. It is proposed to recognize ontogenetical (individual) and evolutionary (historical) aspects of fruit morphogenesis, the first of them we can study directly, while the second aspect can be only hypothesized or treated as a theoretical model of fruit evolution in consequence of some presumed changes in the individual fruit morphogenesis. In this article these aspects are named as "ontomorphogenesis" and "phylomorphogenesis" of the fruit, correspondingly. Our concept of ontomorphogenesis of the fruit involves four components that could not be brought together, such as changes in the morphological structure of the gynoecium, abscission of the extragynecial floral parts and the style, histogenesis of the fruit wall and other fruit parts, and terminal stages of the fruit morphogenesis (dehiscence, splitting, or abscission). The current state of studies of these components in the individual and evolutionary contexts is discussed. By examining the patterns of fruit evolution, we should consider factors acting at both the post-anthetic and pre-anthetic periods of fruit ontomorphogenesis.
Effects of Labelling Quality on Hypertensive Patients’ Knowledge and Adherence in Mataram
Authors: Mariati I Gusti A. D. , Wibowo Yosi I. , Widjaja Karina K. , Setiadi Adji P.
Published: July 2022

Hypertension is a chronic condition that requires long-term treatment, hence, adherence has been a major issue. The dispensed medication label has been commonly used to provide written information to optimize drug use in achieving treatment goals. Therefore, this study aimed to determine the effect of improved labeling quality on knowledge and adherence of hypertensive patients in Mataram. This is a pre-/post-intervention study with improved labeling quality (according to Good Dispensing Practice (GDP) standard–9 attributes) as the intervention. The differences in knowledge, adherence, and blood pressure pre-/post-intervention were statistically tested. A total of 132 patients from 11 Public Health Center in Mataram participated in this study from August to October 2017. The results showed a baseline labeling score of 3.6, and after the intervention (improved labeling), a maximum score of 9 was achieved. Knowledge was significantly increased through improved labeling (median score from 2.0 to 5.0; p=0.001). In addition, the intervention enhanced adherence (median score from 1.0 to 2.0; p=0.001). Significant changes were reported in systolic and diastolic blood pressure pre-/post-intervention (p=0.001 and 0.026, respectively). Therefore, preliminary data were provided on the potential of high-quality labeling to improve knowledge and adherence among hypertensive patients in Mataram.
Informais, empreendedores ou precarizados? A trajetória de trabalhadores de comida de rua
Authors: Nogueira Pinheiro de Oliveira Eveline , Braz de Aquino Cássio Adriano , Simão Nascimento Janequeli
Published: July 2022

Objetivo. Esta pesquisa objetivou a compreensão e a análise da relação entre informalidade, empreendedorismo e precarização de trabalhadores de pequeno porte envolvidos no segmento de comida de rua na cidade de Fortaleza, Estado do Ceará, Brasil. Método. Foram entrevistados, por meio de um roteiro semiestruturado, 10 trabalhadores de comida de rua da cidade de Fortaleza, com idade entre 25 e 73 anos, dentre vendedores de cachorro-quente, milho, tapioca, pastel e outros tipos de produtos alimentícios. Resultados. Uma característica parece surgir como primordial para o trabalhador de comida de rua: ser empreendedor. A falta de perspectiva laboral faz com que os trabalhadores busquem por uma salvação e assim são veiculadas as ideias empreendedoras, focados na informalidade, mas que terminam por reforçar os processos de precarização.
Desarrollo de las reflexiones metapragmáticas sobre la función de la ironía verbal en adolescentes
Authors: Hess Zimmermann Karina , Fernández Ruiz Graciela , Silva López Andrea Minerva , Avecilla Ramírez Gloria Nélida
Published: July 2022

Objetivo. Analizar las reflexiones metapragmáticas que presentan 32 adolescentes de 12 y 15 años de edad (16 por grupo etario) sobre la función de la ironía verbal en dos tipos de actos de habla: agradecimiento y ofrecimiento irónicos. Método. Los participantes se enfrentaron a ocho historias que terminaban con una expresión irónica y mediante un guion de preguntas se indagó sobre las funciones que les atribuían a los enunciados irónicos. Resultados. Se muestran diferencias significativas debidas a la edad, pero no al tipo de enunciado en las reflexiones que hacen los adolescentes, lo que confirma que la capacidad para hacer reflexiones metapragmáticas sobre la ironía verbal se desarrolla de manera muy tardía en el lenguaje infantil.
De la ascendencia a la trascendencia del anthropos: 2001, una odisea prospectiva
Authors: Vargas Campos Ronulfo Alberto
Published: July 2022

La obra de ficción Odisea 2001, en su expresión escrita y cinematográfica, es el motivo para analizar en este trabajo los 3 momentos de la historia humana -ascendencia, decadencia y trascendencia- que identifican al homo sapiens como un ser transitivo, un producto de la evolución autorrealizado pero en riesgo constante de sucumbir a su misma dinámica autopoiética. Según Clarke y Kubrick, el comienzo y ascenso de la especie sapiens radica en la evolución de la inteligencia desde una inducción extraterrestre, premisa que se desprende de la imaginación característica de la ciencia ficción.

El artículo hace una lectura analítica del objeto de estudio, y recurre a fuentes complementarias para contextualizar e interpretar las tesis de Clarke y Kubrick, e inferir conclusiones a partir de ellas. Se toma la perspectiva teórica del crítico de ciencia ficción Julián Díez, quien en su ensayo “Secesión” para la revista Hélice, aplica el concepto de prospección para denominar una categoría del género, que procura elaborar obras que operen como advertencia sobre futuros plausibles pero ingratos; la obra de ciencia ficción prospectiva “avisa sobre posibles desarrollos exacerbados de tendencias presentes en nuestra sociedad con el fin de denunciar su inconveniencia” (Díez 2008, p. 5). Desde esa perspectiva, este artículo determina que la evolución de la inteligencia humana es un medio paradójico: puede, o no, constituirse en medio de supervivencia, instrumento de dominación del ambiente, racionalidad objetiva que induce comportamientos e interacciones autodestructivas y finalmente lucidez autorreflexiva que ampara la posibilidad de evadir la extinción como destino.
Perceptions of Professional and Non-Professional Millennial Men Towards the Street Harassment of Women in San Pedro, San José, Costa Rica
Authors: Sanabria Mora Esteban
Published: July 2022

Street harassment refers to the unwanted comments, gestures, and actions that strangers address to people in public places without the consent of the affected individuals. Although all people regardless of their gender can experience street harassment, this issue has a major incidence on women. This research aimed to examine the perceptions of professional and non-professional millennial men towards the street harassment of women in San Pedro, San José, Costa Rica. The researcher surveyed fifty-two men with the purpose of proving the study’s hypothesis: professional men harass women less frequently than non-professional men. The results revealed the opposite as both male groups harass women almost evenly, and many of them ignore the definition of street harassment and their types.
Competencias docentes para el trabajo en comunidades virtuales de aprendizaje
Authors: Gordon Graell Roberto
Published: July 2022

La educación virtual es un signo de los tiempos modernos. Como fenómeno social intencional cumple con las características generales de la educación, pero la especificidad de su medio la signa con características propias relacionadas con la virtualidad, la tecnología y la disrupción cada vez más corta en el tiempo. El proceso se ve afectado por factores sociales, técnicos, procedimentales y funcionales en el que el rol docente juega un papel fundamental para el logro de un proceso de enseñanza-aprendizaje significativo, efectivo y de calidad para llevar a cabo las funciones y conseguir los objetivos educativos. La realidad latinoamericana es que los docentes universitarios están en desventaja puesto que en su mayoría son migrantes digitales. Más que desventaja técnica es una debilidad de percepción que se trata muy levemente en la literatura especializada. El objetivo de este artículo es analizar las competencias básicas afectivas y de percepción que debe desarrollar un docente para convertirse en facilitador de comunidades virtuales de aprendizaje. Se realizó una revisión bibliográfica centrada en la educación virtual y el rol necesario del docente universitario actual en el entendido de que aún no estamos en el futuro previsto de una sociedad totalmente nativa digital.