bluuebunny/crossref_metadata_2025 huggingface dataset:
Anal and Cervical High-Risk Human Papillomavirus Genotyping in Women With and Without Genital Neoplasia
Authors: Bregar Amy J. , Cronin Beth , Luis Christine , DiSilvestro Paul , Schechter Steven , Pisharodi Latha , Raker Christina , Clark Melissa , Robison Katina
Published: February 2018

Objective

The aim of the study was to compare the prevalence, genotypes, and rates of concomitant anal and cervical high-risk human papillomavirus (HR-HPV) in women with and without a history of HPV-related genital neoplasia.

Materials and Methods

This was a prospective cohort study conducted from December 2012 to February 2014. Women with a history of neoplasia were considered the high-risk group. Women without a history of neoplasia were considered the low-risk group. Cervical and anal cytology and HPV genotyping were performed. All women with abnormal anal cytology were referred for anoscopy.

Results

One hundred eighty-four women met inclusion criteria. High-risk HPV was detected in the anal canal of 17.4% of the high-risk group and 1.5% of the low-risk group (p = .003). High-risk HPV was detected in the cervix of 30.5% of the high-risk group and 7.6% of the low-risk group (p < .001). Concomitant anal and cervical high-risk HPV was detected in 4.4% of the high-risk group and was not detected in the low-risk group (p = .2). Among women with anal intraepithelial neoplasia 2 or greater (n = 5), 60% had HR-HPV detected in the anal canal while none had HR-HPV detected in the cervix.

Conclusions

Women with a history of genital neoplasia are more likely to be positive for anal and cervical HR-HPV compared with women without a history of genital neoplasia. Although there was no significant difference in rates of concomitant HR-HPV between low- and high-risk groups, HR-HPV can be found concomitantly in the anus and the cervix and may be associated with anal intraepithelial neoplasia or carcinoma.
Serum Methylarginines and Hearing Loss in a Population-based Cohort of Older Adults
Authors: McEvoy Mark , Harris David C. , Mangoni Arduino A. , Sarant Julia Z.
Published: February 2018

Objective:

Age-related hearing loss is associated with endothelial dysfunction and increased cardiovascular risk, suggesting a vascular etiology. Methylarginines are endogenous nitric oxide synthase inhibitors that cause endothelial dysfunction and increase cardiovascular disease risk. This study is the first to examine the hypothesis that higher serum concentrations of methylarginines are associated with greater hearing loss prevalence.

Study Design/Patients:

Cross-sectional audiometric data on hearing levels, and serum methylarginines were collected from a population-based sample of 630 older community-dwelling adults.

Results:

Linear regression analysis showed a statistically significant association between higher serum concentrations of asymmetric dimethylarginine (ADMA) and L-arginine and greater degrees of hearing loss for males, particularly over 75 years. Higher body mass index and previous history of stroke were also associated with hearing loss. For females, ADMA concentration was not associated with hearing loss, but higher serum L-arginine concentrations were associated with reduced hearing loss prevalence in older females. Antihypertensive medication use was also associated with reduced hearing loss prevalence. LDL cholesterol and previous myocardial infarction were associated with greater hearing loss.

Conclusion:

This study showed a significant association between serum concentrations of ADMA and hearing loss for males, consistent with the association between endothelial dysfunction and hearing loss. The opposite effect of L-arginine on hearing loss in males versus females might reflect a different role of this precursor toward nitric oxide versus methylated arginines synthesis. These findings are potentially clinically significant if the association between ADMA and hearing loss is causal, as serum methylarginine levels are modifiable through pharmacotherapeutic/lifestyle interventions.
Prelicensure Employment and Student Nurse Self-Efficacy
Authors: Grimm Khristina L.
Published: February 2018

There is a lack of literature regarding how prelicensure employment affects self-efficacy in nursing practice. The purpose of this study was to examine the relationship among prelicensure employment and self-efficacy in nursing practice of senior student nurses. Healthcare experience was identified as the best predictor of positive self-efficacy in managing an assignment of three and four patients. Findings of this study provide insight for providing orientation for newly licensed nurses regarding their readiness to practice.
Longitudinal Study Transformed Onboarding Nurse Graduates
Authors: Slate Kimberly A. , Stavarski Debra H. , Romig Barbara J. , Thacker Karen S.
Published: February 2018

The outcomes of a longitudinal research study on a nurse residency program indicated improvement in the onboarding experience for new graduate nurses. Practice changes and implications for nursing professional development practitioners resulting from the study include the number and orientation of preceptors, program length standardization, and improvement of emergency clinical response education. Additional research studies were implemented to further explore issues novice nurses and their proficient registered nurse colleagues experience throughout the organization.
Transition From Clinical to Educator Roles in Nursing
Authors: Fritz Elizabeth
Published: February 2018

This review identified barriers to and facilitators of nurses’ transition from clinical positions into nursing professional development and other nurse educator roles. The author conducted literature searches using multiple databases. Twenty-one articles met search criteria, representing a variety of practice settings. The findings, both barriers and facilitators, were remarkably consistent across practice settings. Four practice recommendations were drawn from the literature to promote nurses’ successful transition to nursing professional development roles.
Changes in Sugary Beverage Consumption and Public Perceptions in Upstate New York After Implementation of a Community Awareness Campaign and Healthier Vending Strategies
Authors: Durant Danielle J. , Lowenfels Ann , Ren Jia , Brissette Ian , Martin Erika G.
Published: February 2018

Objective:

We evaluated the impact of a community-based healthy beverage procurement and serving practices program, and educational media campaign, on residents' behaviors and beliefs regarding sugary beverages.

Design:

Repeated cross-sectional population surveys in 2013 and 2014 were conducted, as well as semistructured interviews with key informants. We employed multivariate differences-in-differences regression analysis, adjusting for demographics and weight status, using the survey data. Key informant interviews were reviewed for common themes.

Setting:

Three rural counties in upstate New York with high prevalence of children living in poverty and childhood obesity.

Participants:

Residents of Broome, Cattaraugus, and Chautauqua, with Chemung as a control, reached through cross-sectional random-digit-dial landline and cellular telephones, and practitioners involved in intervention implementation.

Intervention:

Community organizations were encouraged through presentations to leadership to adopt healthier vending policies, providing more low- and no-sugar options, and were provided assistance with implementation. In addition, a media campaign supported by presentations to the public aimed to educate residents regarding the health consequences of sugary beverage consumption.

Outcome Measures:

The survey measured population demographics and sugary beverage consumption frequency, availability, beliefs about harmfulness, and support for regulation, pre- and postintervention. Key informant interviews elicited perceived program challenges and successes.

Results:

Compared with temporal trends in the control county, availability of regular soda in the intervention counties decreased (differences-in-differences estimator: β = −.341, P = .04) and support for regulation increased (differences-in-differences estimator: β = .162, P = .02). However, there were no differences regarding beliefs about harmfulness or consumption. Practitioners confirmed that the intervention increased awareness but was insufficient to spur action.

Conclusion:

Although public education on the harmfulness of sugary beverages and provision of healthier options in some vending machines successfully impacted soda availability and support for regulation, it did not reduce consumption. This intervention seems promising but should be paired with other community-based interventions for a more comprehensive approach.
Media Flight Schedules and Seasonality in Relation to Quitline Call Volume
Authors: Murphy-Hoefer Rebecca , Madden Patrick A. , Dufresne Ruth M.
Published: February 2018

Context:

Given the high profile, cost, and vulnerability to budget cuts of mass-reach health education campaigns, researchers have cited the need for media buying strategies.

Objective:

The objective of the current study is to fill a gap in the literature by comparing the impact of media flight schedule types in relation to tobacco quitline call volume.

Design:

The retrospective study was designed to determine whether type of media flight schedule (eg, flighting, continuous, pulsing) impacted number of calls to the Maine Tobacco Helpline, while accounting for number of gross rating points (GRPs), seasonality, holidays, and other factors.

Setting:

Maine has 3 designated market areas (DMAs): Portland/Auburn, Bangor, and Presque Isle.

Main Outcome Measures:

Daily call volume was matched with weekly GRPs.

Methods:

A negative binomial regression model was created to examine the relationship among media flight schedules, number of GRPs, and call volume. Gross rating points reflect national networks and local cable TV media buys. A second model examined the association between GRP dose levels and call volume.

Results:

The number of GRPs was a significant predictor of call volume (P< .001). Weekly number of GRPs within a media flight schedule was the most important indicator for potential effectiveness. Weekly low-dose GRPs were not effective in increasing calls, indicating a minimum threshold. For every 250 GRPs, 29% (or 73) more calls per week were attributed to the media campaigns (P< .001). Weekly quitline call volume was 21% (or 53 calls) lower during the weeks of Christmas, US Thanksgiving, and US Independence Day.

Conclusion:

Type of media flight schedule should be considered in the context of purchasing sufficient weekly, as well as quarterly, rating points to increase tobacco quitline call volume. In addition, our study is the first to quantify and report on lower tobacco quitline call volume during several US holidays.
Neural Decoding of Robot-Assisted Gait During Rehabilitation After Stroke
Authors: Contreras-Vidal Jose L. , Bortole Magdo , Zhu Fangshi , Nathan Kevin , Venkatakrishnan Anusha , Francisco Gerard E. , Soto Rogelio , Pons Jose L.
Published: February 2018

Objective

Advancements in robot-assisted gait rehabilitation and brain-machine interfaces may enhance stroke physiotherapy by engaging patients while providing information about robot-induced cortical adaptations. We investigate the feasibility of decoding walking from brain activity in stroke survivors during therapy using a powered exoskeleton integrated with an electroencephalography-based brain-machine interface.

Design

The H2 powered exoskeleton was designed for overground gait training with actuated hip, knee, and ankle joints. It was integrated with active-electrode electroencephalography and evaluated in hemiparetic stroke survivors for 12 sessions per 4 wks. A continuous-time Kalman decoder operating on delta-band electroencephalography was designed to estimate gait kinematics.

Results

Five chronic stroke patients completed the study with improvements in walking distance and speed training for 4 wks, correlating with increased offline decoding accuracy. Accuracies of predicted joint angles improved with session and gait speed, suggesting an improved neural representation for gait, and the feasibility to design an electroencephalography-based brain-machine interface to monitor brain activity or control a rehabilitative exoskeleton.

Conclusions

The Kalman decoder showed increased accuracies as the longitudinal training intervention progressed in the stroke participants. These results demonstrate the feasibility of studying changes in patterns of neuroelectric cortical activity during poststroke rehabilitation and represent the first step in developing a brain-machine interface for controlling powered exoskeletons.
Endoscopic versus Open In Situ Cubital Tunnel Release: A Systematic Review of the Literature and Meta-Analysis of 655 Patients
Authors: Buchanan Patrick J. , Chieng Lee O. , Hubbard Zachary S. , Law Tsun Y. , Chim Harvey
Published: February 2018

Background:

Cubital tunnel syndrome is the second most common peripheral entrapment syndrome. To date, there is no true consensus on the ideal surgical management. A minimally invasive, endoscopic approach has gained popularity but has not been adequately compared to the more traditional, open approach.

Methods:

With compliance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a systematic review was performed to identify studies published between 1990 and 2016 that compared the efficacy of endoscopic cubital tunnel release to open cubital tunnel release. A meta-analysis was then performed through a random-effects model with inverse variance weighting to calculate I
2 values for heterogeneity analysis. Forest plots were constructed for each analysis group.

Results:

Five studies involving 655 patients (endoscopic cubital tunnel release, n = 226; open cubital tunnel release, n = 429) were included. Meta-analysis revealed no significant superiority of open release in achieving an “excellent” or “good” Bishop score (OR, 1.27; 95 percent CI, 0.59 to 2.75; p = 0.54) and reduction in visual analogue scale score (mean difference, −0.41; 95 percent CI, −1.49 to 0.67; p = 0.46). However, in the endoscopic release cohort, lower rates of new-onset scar tenderness/elbow pain were found (OR, 0.19; 95 percent CI, 0.07 to 0.53; p = 0.002), but there was a higher incidence of postoperative hematomas (OR, 5.70; 95 percent CI, 1.20 to 27.03; p = 0.03). The reoperation rate in the endoscopic and open release groups was 4.9 and 4.1 percent, respectively (p = 0.90).

Conclusions:

The authors demonstrated equivalent overall clinical improvement between endoscopic and open cubital tunnel release in terms of Bishop score and visual analogue scale score reduction. Because of the low power of most studies, further investigations with a larger patient population and longer follow-up are needed to better characterize the role of endoscopic cubital tunnel release.
Reliability of Color Doppler Ultrasound Imaging for the Assessment of Anterolateral Thigh Flap Perforators: A Prospective Study of 30 Perforators
Authors: Debelmas Alexandre , Camuzard Olivier , Aguilar Paola , Qassemyar Quentin
Published: February 2018

Despite numerous advantages, the anterolateral thigh perforator flap suffers from the variable position and nature of its perforators. The aim of the authors’ study was to assess the reliability of preoperative color Doppler ultrasound imaging for the exploration of perforator location and course of anterolateral thigh perforator flaps. A prospective cohort study involving patients for whom head and neck reconstruction was planned with thin anterolateral thigh perforator flaps was conducted. Each patient underwent a color Doppler ultrasound exploration of the thighs, in the operating room, immediately before surgery. The sonographer was the surgeon who raised the flaps. Perforators were sought according to surgical needs, and the same location protocol was followed for all of the cases, using an orthonormal coordinate system to report the passages of the perforators through the vastus lateralis aponeurosis. Between January of 2016 and January of 2017, 22 thin anterolateral thigh perforator flaps were successfully harvested. Thirty perforators were located and used. The median distance between the preoperative color Doppler ultrasound planning and the final location of the perforators was 5 mm, statistically smaller than a 10-mm threshold (p = 0.002). Color Doppler ultrasound effectively predicted the nature of the perforators in 90 percent of the cases. The median duration for perforator color Doppler ultrasound location was 3 minutes, statistically shorter than 10 minutes (p = 0.0001). Preoperative color Doppler ultrasound seems to be reliable, accurate, and compatible with a quick routine assessment during patient setup for the elevation of thin anterolateral thigh perforator flaps.

CLINICAL QUESTION/LEVEL OF EVIDENCE:

Diagnostic, II.
Evaluating Trends in Headache and Revision Surgery following Cranial Vault Remodeling for Craniosynostosis
Authors: Pellicer Elena , Siebold Babette S. , Birgfeld Craig B. , Gallagher Emily R.
Published: February 2018

Background:

The recommended treatment for craniosynostosis, is cranial vault expansion to prevent increased intracranial pressure and optimize developmental outcomes. Some patients complain about postoperative headaches and occasionally require revision to treat increased intracranial pressure. This study examines whether specific factors are associated with an increased risk of postoperative headaches or intracranial hypertension.

Methods:

This retrospective cohort included patients with craniosynostosis from 1995 and 2010. Primary outcomes included headaches and delayed intracranial hypertension. Logistic regression was used to evaluate the associations with clinical characteristics.

Results:

The cohort included 383 patients, of whom 127 (33 percent) complained of headaches. The positive predictive value of a headache indicating intracranial hypertension was only 9.4 percent among all patients and 6.7 percent among patients with nonsyndromic craniosynostosis. Headaches occurring in the morning, more than once per week, and associated with nausea, vomiting, or decreased activity level were most likely to be associated with delayed intracranial hypertension. Only 21 patients (6 percent) required revision surgery, and these patients were more likely to have syndromic craniosynostosis (OR, 5.6; 95 percent CI, 2.1 to 14.9), Chiari malformation (OR, 5.8; 95 percent CI, 1.7 to 19.5), or secondary craniosynostosis (additional sutures fused on the 2-year postoperative CT scan) (OR, 5.4; 95 percent CI, 2.2 to 13.5).

Conclusions:

Headaches are common after cranial vault remodeling but are not very predictive of who will need revision surgery for intracranial hypertension. Patients with specific headache characteristics, syndromic craniosynostosis, secondary synostosis, and Chiari malformations have the highest risk of developing delayed intracranial hypertension.

CLINICAL QUESTION/LEVEL OF EVIDENCE:

Risk, III.
Total HIV-1 DNA Dynamics and Influencing Factors in Long-Term ART-Treated Japanese Adults: A Retrospective Longitudinal Analysis
Authors: Stanoeva Kamelia R. , König André , Fukuda Asami , Kawanami Yoko , Kuwata Takeo , Satou Yorifumi , Matsushita Shuzo
Published: February 2018

Background:

Understanding HIV persistence in treated patients is an important milestone toward drug-free control. We aimed at analyzing total HIV DNA dynamics and influencing factors in Japanese patients who received more than a decade of suppressive antiretroviral treatment (ART).

Methods:

A retrospective study including clinical records and 840 peripheral blood mononuclear cells samples (mean 14 samples/patient) for 59 patients (92% male) was performed. Subjects were divided into 2 groups: with and without hematological comorbidity (mainly hemophilia) plus hepatitis C virus coinfection. Total HIV DNA was measured in peripheral blood mononuclear cells by quantitative polymerase chain reaction. The dynamics, regression over time, and influence of antiretrovirals by group were estimated using a novel regression model (R software v 3.2.3).

Results:

Total HIV DNA decreased on ART initiation, and subsequently, its dynamics varied between groups with previously undescribed fluctuations. If calculated by on-treatment, the mean total HIV DNA levels were similar. The comorbidity group had unstable levels showing different regression over time (P = 0.088/0.094 in year 1/after year 8 of ART) and significantly different treatment responses as shown by antiretroviral group switching estimates. Furthermore, curing hepatitis C virus in hemophiliacs did not significantly alter total HIV DNA levels or regression.

Conclusions:

Our data identified some effects of the long-term treatment on total HIV DNA levels and highlighted the partial influence of comorbidities and coinfections. Total HIV DNA monitoring contributed to therapy response estimates and HIV reservoir quantification. The results suggest that HIV DNA monitoring during ART might be useful as a persistence marker in both HIV-monoinfected patients and those with comorbidities and coinfections.
Bronchiectasis update
Authors: O’Donnell Anne E.
Published: February 2018

Purpose of review

Bronchiectasis, once thought to be an orphan disease, is being diagnosed with increased frequency in the United States and around the world. The present review aims to provide an update on recent publications on the diagnosis and management of bronchiectasis.

Recent findings

Two large bronchiectasis patient registries have published initial reports regarding demographics and other patient data in 2017. Updates on the microbiology, microbiome, and inflammation in patients with bronchiectasis are clarifying the complexities of airway infection in this disease. A consensus definition of ‘exacerbation’ in bronchiectasis has been agreed upon this year. Reports on novel treatments, including the repurposing of older therapies, have also been published in 2016–2017. A new European guideline for the management of adult bronchiectasis is also now available.

Bronchiectasis, a resurgent disease, is now being better defined with a rapidly expanding portfolio of demographic, clinical, and therapeutic research and publications.
Surgical Management of Large Periorbital Cutaneous Defects
Authors: Zou Yun , Hu Li , Tremp Mathias , Jin Yunbo , Chen Hui , Ma Gang , Lin Xiaoxi
Published: February 2018

Purpose

The aim of this study was to repair large periorbital cutaneous defects by an innovative technique called PEPSI (periorbital elevation and positioning with secret incisions) technique with functional and aesthetic outcomes.

Methods

In this retrospective study, unilateral periorbital cutaneous defects in 15 patients were repaired by the PEPSI technique. The ages of patients ranged from 3 to 46 years (average, 19 years). The outcome evaluations included scars (Vancouver Scar Scale and visual analog scale score), function and aesthetic appearance of eyelids, and patient satisfaction. The repair size was measured by the maximum advancement distance of skin flap during operation.

Results

All patients achieved an effective repair with a mean follow-up of 18.3 months. Except one with a small (approximately 0.3 cm2) necrosis, all patients healed with no complication. The mean Vancouver Scar Scale and visual analog scale scores were 2.1 ± 1.7 and 8.5 ± 1.2, respectively. Ideal cosmetic and functional outcomes were achieved in 14 patients (93.3%). All patients achieved complete satisfaction except 1 patient with partial satisfaction. The mean maximum advancement distance of skin flap was 20.2 mm (range, 8–50 mm).

Conclusions

This study demonstrated that the PEPSI technique is an effective method to repair large periorbital cutaneous defects with acceptable functional and aesthetic outcomes.
Reducing Prominent Mandibular Angle Osteotomy Complications
Authors: Chen Hongbo , Sun Jiaming , Wang Jiecong
Published: February 2018

Background

Several methods are available for mandibular reduction, and each method is characterized by unique limitations and complications. However, only a few studies have systematically analyzed these complications. This study aimed to investigate the effects of the outcome of performing curved mandibular angle ostectomy and outer cortex grinding in 1-stage operation and to examine the causes of different types and characteristics of complications.

Methods

The subjects consisted of 528 patients who were subjected to curved mandibular angle ostectomy and outer cortex grinding in 1-stage operation through an intraoral approach. Surgical complications and related factors were recorded, and the rates of complication according to surgeons were simultaneously evaluated.

Results

The esthetic appearance of all of the patients was significantly improved, and they were satisfied with the results of the operation. The complication rate was 5.87%. No serious complications, such as subcondylar fracture, massive bleeding, permanent facial nerve, or asymmetry, occurred. Some complications, including 4 cases of hematoma, 4 cases of severe swelling, 2 cases of infection, and 1 case of sagging face, were detected. The absolute complication rate among faculty members ranged from 3.5% to 11.1%.

Conclusions

Our protocol is an effective method for mandibular angle osteotomy with very few complications. The rate of complications can be effectively reduced, and some serious complications can be avoided because protective measures are improved.
Single-Piece Titanium Plate Cranioplasty Reconstruction of Complex Defects
Authors: Luo Joseph , Morrison David Anthony , Hayes Alex John , Bala Arul , Watts Guy
Published: February 2018

Background:

Different methods have been described for the reconstruction of cranial defects and orbital defects. The complex contouring between the orbital roof and frontal bone creates significant design challenges for prefabricated cranio-orbital reconstructions. In describing the first reported patient of combined skull and orbital roof reconstruction with a single-piece titanium plate cranioplasty, the authors present a new method of combined complex cranio-orbital reconstruction.

Methods:

A 63-year-old lady presented with a large, right-sided frontal en–plaque meningioma involving the right orbit and sphenoid wing. Complete resection would require reconstruction of both the skull and the orbital roof. Surgical preplanning involved marking resection margins on a three-dimensional (3D) printed acrylonitrile-butadiene-styrene model. This margin was used to virtually resect the tumor and generate a repaired surface. A titanium plate was then fabricated using hydrostatic pressing into a 3D-printed mold and the orbital roof portion (a reentrant surface) was hand-finished. Lateral canthus and temporalis muscle suspension holes were prefabricated into the cranioplasty plate.

Results:

The patient underwent hemicraniectomy and tumor resection guided by a custom-made 3D-printed cutting guide. The surgical defect was reconstructed with the prefabricated titanium plate achieving a good functional and cosmetic result.

Conclusion:

Single-piece titanium plate cranioplasty is an effective novel reconstruction method for complex cranio-orbital defects.
Postpartum Depression in Mothers of Infants With Cleft Lip and/or Palate
Authors: Johns Alexis L. , Hershfield Jennifer A. , Seifu Netsanet Mulugeta , Haynes Karla A.
Published: February 2018

This study describes postpartum depression rates and risk factors for mothers with infants with cleft lip and/or palate as postpartum depression has been associated with a range of negative maternal and child outcomes. A retrospective chart review from August 2009 to May 2015 included medical diagnoses, demographics, receipt of prenatal diagnosis, and the Edinburgh Postnatal Depression Scale (EPDS). Mothers (N = 206) had infants (59.2% male; mean age in weeks 5.1 ± 6.9) with isolated cleft lip (18%), cleft palate (22.8%), or cleft lip and palate (59.2%). Mothers ranged from 16 to 45 years old (mean age 29 ± 6.2) and half had received a prenatal diagnosis. Patients mostly had public insurance (57.8%) and represented diverse ethnicities. Based on the EPDS, 11.7% of mothers met the depression cutoff of 10 or higher. The majority endorsed self-blame (68.9%), difficulty coping (59.2%), and feeling anxious (57.3%). Mothers of infants with cleft lip or cleft lip and palate who did not receive a prenatal diagnosis had higher total EPDS scores, anxiety, and incidence of feeling scared. Higher EPDS scores were predicted by not having a prenatal diagnosis and by older maternal age. Mothers of infants with a cleft had similar rates of postpartum depression as the general population; however, those who were older and who did not receive a prenatal diagnosis endorsed more symptoms. Prenatal diagnosis may contribute to positive maternal postpartum adjustment. Providers should incorporate screening for risk factors into their evaluation and treatment planning.
Anatomical and Radiological Investigation of Dry Bone Adult Mandibles Having Impacted Third Molar Teeth
Authors: Cirpan Sibel , Kumbuloglu Ovul , Yonguc Goksin Nilufer , Sayhan Salih , Bulut Burcu , Güvençer Mustafa
Published: February 2018

Objective:

To investigate the incidence of the impacted mandibular third molars in dry bones adult mandibles.

Methods:

The 198 dry bones adult mandibles gathered from the bone collections in Laboratory of the Anatomy Department of Dokuz Eylul University School of Medicine were macroscopically examined for the presence of impacted mandibular third molars. The genders of the adult bones were unknown. The adult mandibles having impacted third molars were photographed with Canon 400B (55 mm objective). The mandibles having impacted third molars were also radiographically examined with orthopantomography (a dental radiographic technique, kV 60, mA 2.0) in radiology unit of Faculty of Dentistry, Ege University. The impacted teeth were grouped according to their position and degree of impaction.

Results:

The each of 2 of 198 adult mandibles (2/198; 1.01%) was having an impacted 3rd molar teeth. These 2 molar teeth were belonged to class 1, B and partially buried, vertically oriented. The first impacted 3rd molar teeth was located on the left side of the one mandible and the second one on the right side of the other mandible.

Conclusion:

The present study provides information about impacted mandibular 3rd molar in dry bones.
Retracted or Withdrawn Publications in Journals Relating to Plastic Surgery
Authors: Hwang Kun , Wu XiaJing
Published: February 2018

The aim of this study was to determine how many papers have been retracted or withdrawn, and for what reason, in journals relating to plastic surgery.

PubMed and SCOPUS were used, with the search terms (retracted OR withdrawn) AND (article OR publication OR paper) AND {(plastic surgery) OR (cosmetic surgery) OR (maxillofacial surgery) OR (craniofacial surgery)}. The papers were analyzed and classified according to the reason for retraction or withdrawal, journal name, publication year, and author. In the PubMed and SCOPUS, 227 and 114 titles were found, respectively, from which 34 duplicate titles were removed. An additional 261 titles which did not include “retracted” or “withdrawn” were removed, leaving 46 papers and 6 mined papers were added. The 52 full texts (42 “retracted” and 10 “withdrawn”) were analyzed.

The most frequent reason for retraction or withdrawal was duplication (17, 32.7%) followed by the author's request (9, 17.3%), plagiarism (7, 13.5%), and lack of permission (5, 9.6%). Retraction was most common in Plast Reconstr Surg (6, 12%) followed by Aesthetic Plast Surg (4, 7.9%), Ann Plast Surg (2, 3.9%), J Plast Reconstr Aesthet Surg (2, 3.9%), and Surg Res (2, 3.9%). Most authors retracted a paper just once; however, 6 authors retracted a paper twice or more. The first retraction was found in 1991, and the number of retractions showed a tendency to increase over time. However, the duplication rate did not change over time (R
2 = 0.178, P = 0.117).

Journal reviewers, as well as production editors, should check for duplication, plagiarism, or permission-related problems.
Respiratory Obstruction Due to Richards Type 4 Fracture
Authors: Pires Willian Ricardo , Santos Gabriel Mulinari , Reis Erik Neiva Ribeiro de Carvalho , de Oliva André Hergesel , Jacob Ricardo Garcia Mureb , Faverani Leonardo Perez , Souza Francisley Ávila , Júnior Idelmo Rangel Garcia
Published: February 2018

Facial fractures can be potentially fatal in polytraumatized patients due to retropositioning tissues to upper airway obstruction. In the first aids, this situation can be reversed using a tracheostomy procedure to break out the airways. However, fractures leading to airway obstruction are rare and according to Richards Classification can be classified into 5 types. The purpose of this article is to report a clinical patient with a bilateral condylar and mandibular symphysis fractures that resulted in airway obstruction and severe mandibular rear projection.
Early Tarsorrhaphy in Conjunctival Chemosis After Orbit Bone Reconstruction
Authors: Deng Yuan , Li Zhengkang
Published: February 2018

Objective:

Chemosis is a common occurrence after orbital reconstruction surgery by the transconjunctival approach. The authors propose an early tarsorrhaphy approach for treating severe conjunctival chemosis following orbital fracture repair.

Methods:

All severe conjunctival chemosis patients following orbital fracture repair were divided into 2 groups: tarsorrhaphy performed immediately when the eyelids could not close completely due to prominent conjunctival edema (early tarsorrhaphy, n = 10); and tarsorrhaphy performed 3 days after the appearance of severe chemosis (delayed tarsorrhaphy, n = 10). Once the conjunctiva subsided, the sutures were immediately removed. The duration of conjunctival edema was recorded.

Results:

The average time to resolution of severe chemosis was significantly shorter in the early versus delayed tarsorrhaphy group (3.5 ± 0.5 versus 7.2 ± 1.73 days, P < 0.05). No recurrence of conjunctival edema occurred in any patient 4 months postoperatively.

Conclusions:

Early temporary tarsorrhaphy is a fast and effective method for the treatment of conjunctival chemosis following orbital fracture surgery. The sooner eyelid suturing is performed, the faster conjunctival chemosis will subside.
Outcome of Conventional Adipose Tissue Grafting for Contour Deformities of Face and Role of Ex Vivo Expanded Adipose Tissue-Derived Stem Cells in Treatment of Such Deformities
Authors: Bashir Muhammad Mustehsan , Sohail Muhammad , Bashir Afzaal , Khan Farid Ahmad , Jan Sadia Nosheen , Imran Muhammad , Ahmad Fridoon Jawad , Choudhery Mahmood S.
Published: February 2018

Objectives:

To evaluate the outcomes of conventional fat grafting for facial contour deformities and to describe clinical outcome of a patient with contour deformity of face treated with ex vivo expanded adipose tissue-derived mesenchymal stem cells (ASCs) enriched fat graft.

Place and Duration of Study:

The Department of Plastic Surgery and Tissue Engineering and Regenerative Medicine Laboratory, King Edward Medical University/Mayo Hospital, Lahore, from September 2015 to September 2017.

Methods:

Patients with contour deformities of face requiring soft tissue augmentation were included. Fat was harvested, processed, and injected following a standard protocol. Both subjective and objective assessments were performed and complications were also noted.

Results:

Twenty-five patients underwent 51 fat-grafting sessions over a period of 24 months. Eighteen (72%) patients underwent multiple fat-grafting sessions. Mean (standard deviation) soft tissue thickness after 72 hours and 6 months of first fat graft session was 18.62 (7.2) and 12.88 (6.21) mm, respectively, which corresponds to 30.77 (13)% reduction of transplanted fat. Physician and patient assessment scores were 3.42 (0.92) and 4 (1.04), respectively. Few minor complications were observed. In the patient undergoing ex vivo expanded ASCs enriched fat graft, there was minimal decrease in soft tissue thickness of treated area (44 mm vs 42 mm) 6 months postoperatively and patient was highly satisfied with the outcome after the single session.

Conclusion:

Conventional fat grafting is safe for correction of facial contour deformities. However, procedure needs to be repeated multiple times to produce satisfactory results. Beneficial effects of ex vivo expanded ASCs enriched fat grafting have a potential to alter the current treatment paradigm of fat grafting for soft tissue reconstruction.
Spring-Assisted Surgery in the Treatment of Complex Craniosynostosis
Authors: Bevilacqua Ruggero , Tarnow Peter , Kölby Lars , Maltese Giovanni
Published: February 2018

Multisutural nonsyndromic craniosynostosis is a rare group of malformations, whose frequency has been reported between 3% and 7% of all craniosynostosis. The clinical diagnosis can be difficult and computed tomography is usually required. Surgical treatment is challenging and staged procedures are performed in up to 80% of patients. The aim of the present study was to determine the reoperation rate and to evaluate the surgical outcomes by measuring intracranial volume (ICV) preoperatively and at follow-up, and comparing it to a control group. Perioperative variables and reoperation rate were recorded. Fifty-one patients presented with a complex pattern of synostosis without a recognizable syndrome (5% of cases of total patients evaluated). Fifteen patients have been treated with spring-assisted surgery, either alone or in combination with a foreheadplasty. The mean follow-up was 6.2 years. The mean preoperative ICV of the patients was smaller, but not significantly, than in the normal population (P = 0.13). Postoperatively, the mean ICV was similar to that of the control group at 1 year (P = 0.92), while at 3 years it was appreciably smaller, although not significantly different (P = 0.06). Five patients (33%) went through a secondary skull expansion for either raised intracranial pressure or cosmetic reasons. Spring-assisted surgery seems to temporarily expand ICV in children with complex synostosis and lower the reoperation rate, thus reducing the need for a second procedure. A longer follow-up would be necessary to further investigate the effects of springs over time.
Removal of the Residual Roots Displaced Into the Maxillary Sinus via Endoscopy
Authors: Wang Xunming , Li Shihao , Huang Zhiquan , Cai Qian , Huang Zixian , Chen Weiliang
Published: February 2018

Minimally invasive endoscopic surgery has been developed for various indications in the craniomaxillofacial area.
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The case report presented in this article is focused on the possibility of removing the residual roots displaced into the maxillary sinus by means of an endoscopic technique. When planning endoscopic surgery to access the residual roots displaced in the maxillary sinus, we performed 2 different approaches into the maxillary sinus, a transnasal approach through the middle or inferior turbinate and transoral approach via the anterior maxillary sinus wall. The endoscopic surgical approach described is reliable and minimally invasive for removing the residual roots displaced into the maxillary sinus. Therefore, we concluded that the application of this clinical procedure is worth promoting.
The Relationship Between Cephalogram Analysis and Oxygen Desaturation Index During Sleep in Patients Submitted for Mandibular Setback Surgery
Authors: Dahy Khaled Gamal , Takahashi Katsu , Saito Kazuyuki , Kakeno Azumi , Kiso Honoka , Isobe Yu , Mishima Sayaka , Asai Keita , Moussa Abd-Elmateen , Shahat Badawy , Rezk Ibrahim , Oga Toru , Morita Satoshi , Chin Kazuo , Bessho Kazuhisa
Published: February 2018

Objectives:

The aim of this study was to examine the relationship between morphologic factors of mandibular protrusion patients and clinical indices of obstructive sleep apnea (OSA).

Methods:

Fifty-two Japanese patients divided into 2 groups: 1 jaw surgery group (30 patients) and 2 jaw surgery group (22 patients). Morphologic changes were studied using cephalograms taken before surgery and 1 year after surgery. Functional changes studied using impulse oscillometry and pulse oximetry during sleep, both of which are clinically useful measures in assessing OSA, taken before surgery and 1 year after surgery.

Result:

Lower face cage area significantly decreased in 1 jaw group than in 2 jaw group patients. Positive significant correlation was found between changes in 3% oxygen desaturation index (ODI) and changes of tongue area and vertical position of the hyoid bone in 1 jaw surgery group. Multiple regression analysis indicates that tongue area and airway area were independently significant predictors of 3% ODI in 1 jaw group patients.

Conclusion:

In 2 jaw surgery, maxillary surgery compensated for the effect of mandibular setback surgery. Mandibular setback surgery to mandibular protrusion patients was performed within the range of adequate movement distance, but precautions for risk of postoperative obstructive sleep apnea syndrome should be considered.
Surgical Treatment Outcomes of Vocal Process Granuloma After Endotracheal Intubation
Authors: Lee Dong Hoon , Yoon Tae Mi , Lee Joon Kyoo , Lim Sang Chul
Published: February 2018

Introduction:

The objective of this study was to review the clinical characteristics and surgical treatment outcomes of the vocal process granuloma after the endotracheal intubation.

Methods:

A retrospective chart review was performed at Chonnam National University Hwasun Hospital from January 2008 to December 2015.

Results:

Twenty-one vocal process granulomas after endotracheal intubation were diagnosed in 13 patients. The most common symptom was hoarseness. Among 13 patients, bilateral vocal process granulomas were in 8 patients. For the remaining 5 patients, their unilateral vocal process granulomas were all left-sided. All the cases of vocal process granulomas after the endotracheal intubation were treated by laryngoscope microsurgery under general anesthesia. Recurrence of vocal process granulomas was identified in 1 lesion.

Conclusion:

This study suggests that surgery for vocal process granuloma after endotracheal intubation is a good treatment option for a rapid resolution of lesions and the associated symptoms, along with having low recurrence rates.
Evaluation of Mandibular Lingual Foramina With Cone-Beam Computed Tomography
Authors: Zhang Chunan , Zhuang Longfei , Fan Linfeng , Mo Jiaji , Huang Zhuoli , Gu Yingxin
Published: February 2018

The aim of this study was to evaluate the characteristics of 3 kinds of mandibular lingual foramina through cone beam computed tomography images to analyze its diameter, frequency, location and its correlation with age in southeast Chinese mainland population. Lingual foramina in 299 patients were grouped into midline lingual foramina (MLF), lateral lingual foramina (LLF), and nutrient foramina (NF) with diameters and frequency measured. Vertical distances from foramina to mandibular inferior border were recorded as Hinf. Data were analyzed using ANOVA, independent sample t tests and Pearson correlation. Results showed that MLF had a frequency of 99.3% at midline symphysis. Average diameter and Hinf of MLF were 0.65 ± 0.19 and 13.79 ± 2.15 mm, respectively. Lateral lingual foramina had a frequency of 63.2% with the majority observed in premolar region. Average diameter and Hinf of LLF were 0.62 ± 0.19 and 6.90 ± 1.88 mm, respectively. Nutrient foramina had a frequency of 91.3% and was most frequently detected between mandibular incisors. Average diameter and Hinf of NF were 0.57 ± 0.15 and 28.39 ± 2.38 mm, respectively. Mean diameter of MLF and NF of each patient correlated with age (r = 0.174 and 0.201, respectively, P < 0.05). No statistical correlation was observed between average diameter of LLF and age (r = 0.114, P > 0.05). Preoperative cone beam computed tomography is a valuable aid in locating lingual foramina, which could be used as an indication to avoid unwanted hemorrhage in implant surgery.
Perceptions of Healthy-Looking and Sexy-Looking Brow Thickness
Authors: Hwang Kun , Kim Hun
Published: February 2018

This study aims to determine which brow thickness levels were considered ideal, healthy-looking, young-looking, and sexy-looking by Koreans.

The 163 women and 38 men who visited a brow bar were asked to view illustrations of 4 brow thickness levels defined in terms of the percentage of the eye width at the lateral canthus: very thin (VTn-1/6) (16% of eye width), thin (Tn-1/5) (20%), medium (Med-1/4) (25%), and thick (Tk-1/3) (33%) and to choose which they thought were ideal, young-looking, healthy-looking, and sexy-looking.

Med-1/4 (61.2%) was the brow thickness most often considered to be ideal, followed by Tk-1/3 (17.4%) and Tn-1/5 (15.9%). VTn-1/6 was the least preferred (5.5%). Med-1/4 was the most preferred ideal thickness among both sexes. Tk-1/3 (40.8%) was the thickness most often considered to be young-looking, followed by Med-1/4 (35.3%) and Tn-1/5 (18.4%). VTn-1/6 was the least preferred (5.5%). Tk-1/3 was the most preferred young-looking thickness among both sexes. Tk-1/3 (48.8%) was the thickness most often considered to be healthy-looking, followed by Med-1/4 (30.8%) and Tn-1/5 (11.9%). VTn-1/6 was the least preferred (8.5%). Tk-1/3 was the most preferred healthy-looking thickness by women (52.2%), whereas Med-1/4 was the most common choice among men (39.5%). Tn-1/5 (40.8%) was the thickness most often considered to be sexy-looking, followed by VTn-1/6 (25.9%) and Med-1/4 (21.4%). Tk-1/3 was the least preferred (11.9%). Tn-1/5 was the most preferred sexy-looking thickness among both sexes.

The results may be used as guidelines for patient or customer preferences in facial rejuvenation operations, brow esthetics, or tattooing.
Juvenile Nasopharyngeal Angiofibroma With Sphenoid Sinus Invasion and Protrusion: Treatment Approach With Le Fort I Osteotomy
Authors: Heitz Claiton , Weber Alexandre , Dini Leandro , Louzada Guilherme Pivatto , Lombardo Eduardo
Published: February 2018

Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumor that occurs predominantly in young males. The authors report the case of a 22-year-old male patient who presented with a painless, exophytic tumor mass protruding through the right nostril, with anterior lateral extension associated with severe posterior involvement, erosion of the sphenoid bone to the right of the pterygoid process, and significant epistaxis. The preoperative evaluation, surgical approach, postoperative results, and a review of the literature are presented. The surgical approach with Le Fort I osteotomy was designed to facilitate surgical access to the tumor in the nasal cavity. Before down-fracture of the maxilla, plates were placed for fixation and holes were made to produce reference points for restoration of normal anatomy after tumor removal. Although the literature describes the use of nonsurgical therapies, it is well established that surgical treatment is the best option for patients with JNA. Treatment also requires preoperative embolization to avoid bleeding and ensure safety during tumor resection. Long-term imaging follow-up every 6 to 8 months for at least 3 years after surgery is needed for detection of residual tumor/recurrence. The modified technique used here together with preoperative embolization was essential to successful outcome.