bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table S24 from Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies LMO2/STAG2 Rearrangements as Extremely High Risk
Authors: Kimura Shunsuke , Park Chun Shik , Montefiori Lindsey E. , Iacobucci Ilaria , Pölönen Petri , Gao Qingsong , Arnold Elizabeth D. , Attarbaschi Andishe , Brown Anthony , Buldini Barbara , Caldwell Kenneth J. , Chang Yunchao , Chen Chelsey , Cheng Cheng , Cheng Zhongshan , Choi John , Conter Valentino , Crews Kristine R. , de Groot-Kruseman Hester A. , Deguchi Takao , Eguchi Mariko , Muhle Hannah E. , Elitzur Sarah , Escherich Gabriele , Freeman Burgess B. , Gu Zhaohui , Han Katie , Horibe Keizo , Imamura Toshihiko , Jeha Sima , Kato Motohiro , Chiew Kean H. , Khan Tanya , Kicinski Michal , Köhrer Stefan , Kornblau Steven M. , Kotecha Rishi S. , Li Chi-Kong , Liu Yen-Chun , Locatelli Franco , Luger Selina M. , Paietta Elisabeth M. , Manabe Atsushi , Marquart Hanne V. , Masetti Riccardo , Maybury Mellissa , Mazilier Pauline , Meijerink Jules P.P. , Mitchell Sharnise , Miyamura Takako , Moore Andrew S. , Oshima Koichi , Pawinska-Wasikowska Katarzyna , Pieters Rob , Prater Mollie S. , Pruett-Miller Shondra M. , Pui Ching-Hon , Qu Chunxu , Reiterova Michaela , Reyes Noemi , Roberts Kathryn G. , Rowe Jacob M. , Sato Atsushi , Schmiegelow Kjeld , Schrappe Martin , Shen Shuhong , Skoczeń Szymon , Spinelli Orietta , Stary Jan , Svaton Michael , Takagi Masatoshi , Takita Junko , Tang Yanjing , Teachey David T. , Thomas Paul G. , Tomizawa Daisuke , Trka Jan , Varotto Elena , Vincent Tiffaney L. , Yang Jun J. , Yeoh Allen E.J. , Zhou Yinmei , Zimmermann Martin , Inaba Hiroto , Mullighan Charles G.
Published: October 2024

Lists of T-ALL related genes for filtering tumor-only and RNAseq samples.
Supplementary Fig. S2 from Perivascular NOTCH3+ Stem Cells Drive Meningioma Tumorigenesis and Resistance to Radiotherapy
Authors: Choudhury Abrar , Cady Martha A. , Lucas Calixto-Hope G. , Najem Hinda , Phillips Joanna J. , Palikuqi Brisa , Zakimi Naomi , Joseph Tara , Birrueta Janeth O. , Chen William C. , Oberheim Bush Nancy A. , Hervey-Jumper Shawn L. , Klein Ophir D. , Toedebusch Christine M. , Horbinski Craig M. , Magill Stephen T. , Bhaduri Aparna , Perry Arie , Dickinson Peter J. , Heimberger Amy B. , Ashworth Alan , Crouch Elizabeth E. , Raleigh David R.
Published: October 2024

Supplementary Fig. 2. Single-cell RNA sequencing of dog meningiomas. A, Single-cell counts across UMAP clusters from dog meningioma samples analyzed using single-cell RNA sequencing. B, UMAP showing single-cell RNA sequencing of dog meningioma samples shaded by sample of origin. C, UMAP showing single-cell RNA sequencing cell cycle analysis across dog meningioma samples. D-E, Heatmapt and feature plots showing differentially expressed genes across UMAP clusters from dog meningioma samples analyzed using single-cell RNA sequencing. Colors as in A. F, Magnetic resonance imaging (MRI, left) or H&E images (right) of spontaneous dog meningiomas. Scale bars, 100µm. See also Supplementary Table 2.
Supplementary Fig. S16 from Perivascular NOTCH3+ Stem Cells Drive Meningioma Tumorigenesis and Resistance to Radiotherapy
Authors: Choudhury Abrar , Cady Martha A. , Lucas Calixto-Hope G. , Najem Hinda , Phillips Joanna J. , Palikuqi Brisa , Zakimi Naomi , Joseph Tara , Birrueta Janeth O. , Chen William C. , Oberheim Bush Nancy A. , Hervey-Jumper Shawn L. , Klein Ophir D. , Toedebusch Christine M. , Horbinski Craig M. , Magill Stephen T. , Bhaduri Aparna , Perry Arie , Dickinson Peter J. , Heimberger Amy B. , Ashworth Alan , Crouch Elizabeth E. , Raleigh David R.
Published: October 2024

Supplementary Fig. 16. NOTCH3 inhibition blocks meningioma xenograft growth without causing toxicity. A, A NOTCH1 negative regulatory region neutralizing antibody (αNRR1), but not αNRR3, causes diarrhea and rash resulting in weight loss in mice harboring meningioma xenografts. Antibodies were delivered using biweekly IP injection. Student’s t tests. B, The -secretase inhibitor LY-411575 (GSI) delivered using daily IP injection causes diarrhea and rash resulting in weight loss in mice harboring meningioma xenografts. Student’s t tests. C, LY-411575 attenuates the growth of CH-175MN (left) or IOMM-Lee (right) meningioma xenografts in mice. Student’s t tests. Lines represent means and error bars represent standard error of means.
Supplementary Figure S1 from Oncogenic KRAS-Dependent Stromal Interleukin-33 Directs the Pancreatic Microenvironment to Promote Tumor Growth
Authors: Donahue Katelyn L. , Watkoske Hannah R. , Kadiyala Padma , Du Wenting , Brown Kristee , Scales Michael K. , Elhossiny Ahmed M. , Espinoza Carlos E. , Lasse Opsahl Emily L. , Griffith Brian D. , Wen Yukang , Sun Lei , Velez-Delgado Ashley , Renollet Nur M. , Morales Jacqueline , Nedzesky Nicholas M. , Baliira Rachael K. , Menjivar Rosa E. , Medina-Cabrera Paola I. , Rao Arvind , Allen Benjamin , Shi Jiaqi , Frankel Timothy L. , Carpenter Eileen S. , Bednar Filip , Zhang Yaqing , Pasca di Magliano Marina
Published: October 2024

Figure S1: IL-33+ stromal cells are abundant in human and mouse PDA.
Can Ruxolitinib CrashTET2- andIDH2-Driven Clonal Hematopoiesis?
Authors: Khabusheva Elmira , Goodell Margaret A.
Published: October 2024

In this issue, Waarts and colleagues developed an advanced ex vivo CRISPR screening platform to identify vulnerabilities in clonal hematopoiesis (CH). This unique system allowed the authors to identify a link between IDH2 and TET2 CH mutations, histone demethylases, and altered cytokine signaling, which enabled targeting by ruxolitinib leading to the elimination of CH clones, offering a possible path for preventing the development of malignancy.

See related article by Waarts et al., p. 1860
Transient EZH2 Suppression by Tazemetostat during In Vitro Expansion Maintains T-Cell Stemness and Improves Adoptive T-Cell Therapy
Authors: Hou Yingqin , Zak Jaroslav , Shi Yujie , Pratumchai Isaraphorn , Dinner Brandon , Wang Wenjian , Qin Ke , Weber Evan W. , Teijaro John R. , Wu Peng
Published: October 2024

The histone methyltransferase enhancer of zeste homolog 2 (EZH2) plays important roles in T-cell differentiation, proliferation, and function. Previous studies have demonstrated that genetic deletion of EZH2 in CD8+ or total T cells impairs their antiviral and antitumor activities, cytokine production, and ability to expand upon rechallenge. Contrary to the detrimental role of deleting T cell–intrinsic EZH2, in this study, we demonstrated that transient inhibition of EZH2 in T cells prior to the phenotypic onset of exhaustion with a clinically approved inhibitor, tazemetostat (Taz), delayed their dysfunctional progression and preserved T-cell stemness and polyfunctionality but had no negative impact on cell proliferation. Taz-induced T-cell epigenetic reprogramming increased the expression of the self-renewal T-cell transcription factor TCF1 by reducing H3K27 methylation at its promoter preferentially in rapidly dividing T cells. In a murine melanoma model, T cells depleted of EZH2 induced poor tumor control, whereas adoptively transferred T cells pretreated with Taz exhibited superior antitumor immunity, especially when used in combination with anti–PD-1 blockade. Collectively, these data highlight the potential of transient epigenetic reprogramming by EZH2 inhibition to enhance adoptive T-cell immunotherapy.
Table 2 from Health Disparities among Patients with Cancer Who Received Molecular Testing for Biomarker-Directed Therapy
Authors: Heath Elisabeth , Dyson Gregory , Ribeiro Jennifer R. , Xiu Joanne , Poorman Kelsey , Mamdani Hirva , Al-Hallak Mohammed N. , Shields Anthony F. , Elayoubi Jailan A. , Winer Ira S. , Cackowski Frank C. , Puckrein Gary A. , Lopes Gilberto de Lima , Jones Nathaniel , Hauke Ralph J. , Kareff Samuel A. , Radovich Milan , Sledge George W. , Spetzler David B. , Vidal Gregory A. , Marshall John L.
Published: October 2024

COXPH model for all patients in the cohort
Supplementary Figure S3 from Health Disparities among Patients with Cancer Who Received Molecular Testing for Biomarker-Directed Therapy
Authors: Heath Elisabeth , Dyson Gregory , Ribeiro Jennifer R. , Xiu Joanne , Poorman Kelsey , Mamdani Hirva , Al-Hallak Mohammed N. , Shields Anthony F. , Elayoubi Jailan A. , Winer Ira S. , Cackowski Frank C. , Puckrein Gary A. , Lopes Gilberto de Lima , Jones Nathaniel , Hauke Ralph J. , Kareff Samuel A. , Radovich Milan , Sledge George W. , Spetzler David B. , Vidal Gregory A. , Marshall John L.
Published: October 2024

Overall survival by RUCA code and poverty
Investigation of Herbal Therapy Methods Used by Parents of Children with Cancer for Symptom Management in Chemotherapy Process
Authors: Erbay Nurcan , Canbulat Sahiner Nejla , Aydın Mehmet Fatih
Published: October 2024

Introduction: The number of types of cancer, which is the leading severe health problem and is frequently seen in childhood period, has steadily increased over the years. This descriptive and cross-sectional study was conducted to determine the herbal treatment methods used by parents of children with cancer during the chemotherapy process for symptom management. Methods: The study was carried out with the parents of 126 children diagnosed with cancer. The data were collected with a questionnaire form created in line with the literature and the form for the amount and frequency of use of herbal treatment methods used by parents. The data were evaluated with descriptive statistics and χ2 test. Results: The mean age of the children included in the study was 8.08 ± 3.15 (min = 3, max = 17) years, and the mean duration of diagnosis was 14.35 ± 13.22 (min = 6, max = 60) months. 78.6% (n = 99) of the parents included in the study stated that they used herbal treatment for the treatment of their child’s disease. 79.4% (n = 100) of the parents thought that the herbal treatment they used was effective. The first reason (48.4%, n = 61) for using herbal treatment was “to do everything we could for the treatment.” Conclusion: It was determined that the use of herbal treatment methods was related to the mother’s profession, the education level of the parents, and the place of residence. In particular, it is necessary to inform parents about herbal treatment methods through nurses with up-to-date information and to create the right attitude toward this issue.
Differences in Foot Morphology across Age Groups for Women Active in Sport
Authors: Reeves Joanna , Buckley Roxana , Dixon Sharon
Published: October 2024

Introduction: Foot morphology in the general population has been shown to change with age, and active older adults have reported a need for wide-fitting footwear. Methods: This study recruited 374 women active in racket sports and team sports in the UK who had their feet scanned while 50% weight bearing. Participants were grouped into 10-year age bands ranging from 18–29 years to 70–79 years. Data analysis was performed on the widths, heights, and circumferences of participants’ right feet normalised to foot length, as well as an assessment of hallux valgus angle and deformity. Results: The 18–29-year group had significantly smaller measures of foot width, ball of foot circumference and short heel circumference (p < 0.05, η2 = 0.042, η2 = 0.056) compared to the older groups. The foot dorsum height and circumference at 50% foot length were significantly less in the oldest age groups compared to the middle age groups (p = 0.0001, η2 = 0.055 and p = 0.0007, η2 = 0.044, respectively). There was some evidence of increased hallux valgus deformity with age. Conclusion: Designers and manufacturers of athletic footwear should be aware of the changes in foot morphology with age in order to provide more inclusive footwear.
Urbanization and Child Development
Authors: Sen Umay , Gredebäck Gustaf
Published: October 2024

In recent decades, the rate of urbanization has been rapid, transforming the world and the people that take part in this global trend. Urbanization has often been studied and discussed with a focus on adults, societies, and social dynamics, without an emphasis on the psychological processes of young members of society, the children that grow up in transition. This review aims to address the significant and complex relationship between urbanization and child development, focusing on physical health, mental health, and cognitive outcomes. By outlining some of the links between socioeconomic themes associated with urbanization (i.e., internal migration, poverty, income inequality, neighborhoods, and discrimination) and by discussing their role in development, the present review situates the child in the urban context. Taken together, the relevant evidence suggests that urbanization, as a multidimensional construct, brings benefits and poses some risk factors for development. Therefore, a greater focus on the characteristics of the economic, cultural, and social context shaped by urbanization is essential for an in-depth understanding of urbanization and child development.
Global and Regional Burden of Vaccine-Associated Erythema Multiforme and Their Related Vaccines, 1967–2023: An In-Depth Analysis of the World Health Organization Pharmacovigilance Database
Authors: Kyung Seoyeon , Rahmati Masoud , Kang Jiseung , Lee Kyeogmin , Lee Hayeon , Yon Dong Keon
Published: October 2024

Objective: Vaccine-associated erythema multiforme (EM) remains under-researched, impacting global vaccine safety evaluations. This study examines the global and regional burden of EM and its association with specific vaccines to optimize vaccination strategies. Subject and Methods: We analyzed data from the WHO pharmacovigilance database on vaccine-associated EM from 1967 to 2023 (n = 131,255,418 reports). Reporting frequencies, reported odds ratios (RORs), and information components (IC) were calculated for 16 vaccines across 170 countries. Results: We identified 6,355 cases (males, n = 3,182 [50.07%]) of vaccine-associated EM from a total of 46,378 reports of all-cause EM. While vaccine-associated EM has been consistently reported, there has been a notable increase in reported incidence particularly in 2010 and 2020. Measles, mumps, and rubella vaccines had the highest association with vaccine-associated EM reports (ROR: 8.75 [95% confidence interval, 8.11–9.44]; IC, 3.10 [IC0.25, 2.97]), followed by hepatitis B (8.54 [7.66–9.51]; 3.06 [2.88]), hepatitis A (8.11 [7.01–9.39]; 2.98 [2.74]), typhoid (6.50 [4.75–8.90]; 2.60 [2.07]), encephalitis (5.86 [4.35–7.91]; 2.47 [1.96]), diphtheria, tetanus toxoids, pertussis, polio, and Hemophilus influenza type b (5.70 [5.42–5.99]; 2.46 [2.38]), pneumococcal (5.56 [5.11–6.06]; 2.45 [2.31]), rotavirus (4.96 [4.21–5.84]; 2.29 [2.01]), varicella-zoster (4.44 [3.99–4.95]; 2.13 [1.95]). Vaccine-associated EM reports were more strongly correlated with younger age groups and males. The overall fatality rate of vaccine-associated EM was 0.04%. Conclusions: The rise in vaccine-associated EM across multiple vaccines, especially in younger populations, highlights the need for closer monitoring and more informed vaccination practices to mitigate adverse reactions.
Validation of Prognostic Scales for Functional Outcome in Ischemic Stroke Patients Treated with Intravenous Thrombolysis in a Rural Setting
Authors: Loggini Andrea , Saleh Velez Faddi G. , Hornik Jonatan , Henson Jessie , Wesler Julie , Hornik Alejandro
Published: October 2024

Introduction: Early prediction of functional outcome after rtPA helps clinicians in prognostic conversations with stroke patients and their families. Three prognostic tools have been developed in this regard: DRAGON, MRI-DRAGON, and S-TPI scales. These tools, all performing with comparable accuracy, have been internally and externally validated in tertiary care centers. However, their performance in rural areas remains uncertain. This study addresses this gap in the literature by evaluating the effectiveness of those prognostic tools in stroke patients treated in a rural area of the Midwest. Methods: We conducted a retrospective study of stroke patients treated with thrombolytics at Southern Illinois Healthcare Stroke Network from July 2017 to June 2024. Data on demographics, clinical presentations, laboratory values, neuroimaging, and stroke metrics were collected. Modified Rankin Scale (mRS) at 1 month, classified into good (mRS ≤2) and poor (mRS ≥5) outcomes were noted. DRAGON and MRI-DRAGON scores were calculated. S-TPI model was built. Area under the receiver operating characteristic curve (AUC) with its 95% confidence interval was calculated for each prognostic model. Results: A total of 279 patients were included in this study. Of those, 43% (n = 119) were male. Median age (interquartile range [IQR]) was 69 (57–80) years. NIHSS at presentation (IQR) was 7 (4–13). 12% of the cohort (n = 34) had posterior circulation stroke. At 1 month, 66% of patients (n = 185) had mRS ≤2, whereas 14% of patients (n = 39) had mRS ≥5. MRI-DRAGON showed the highest accuracy in predicting both good (AUC = 0.86, 95% CI: 0.81–0.90) and poor outcomes (AUC = 0.84, 95% CI: 0.76–0.91). DRAGON also demonstrated high accuracy for good (AUC = 0.85, 95% CI: 0.80–0.89) and poor (AUC = 0.82, 95% CI: 0.75–0.90) outcomes. Conversely, in our population, the S-TPI model had the lowest accuracy for good (AUC = 0.56, 95% CI: 0.49–0.63) and poor (AUC = 0.68, 95% CI: 0.61–0.76) outcomes. Conclusion: Among the available grading scores, MRI-DRAGON score can be considered the more accurate short-term prognostic tool for stroke patients treated with rtPA in the rural setting.
Comparative Analyses Reveal Conserved and Modified Steps in the Testis Descent and Scrotum Development in Mouse and Opossum
Authors: Wakamatsu Yoshio , Takeda Yawara , Tamura Koji , Suzuki Kunihiro , Kiyonari Hiroshi , Yamada Gen
Published: October 2024

Introduction: In many mammals, the testes descend from its abdominal position on the mesonephric kidney and are housed in the scrotum. It has been speculated that metatherians and eutherians might have acquired the scrotal testis independently because metatherians have the scrotum cranially to the phallus, while eutherians, such as humans and mice, possess it caudally. Rather, recent studies based on sequence comparisons of testis-descent-related genes indicate that the metatherian-eutherian common ancestor might already possess the descent mechanisms. To further elucidate the path of scrotal testis evolution, it is informative to compare the processes of the descent and scrotum development between metatherian and eutherian model animals. Methods: In this study, we histologically and molecularly compare these processes in gray short-tailed opossum (Monodelphis domestica), the most commonly used metatherian experimental model, and compare them with those in mouse. Results: Our observations indicate that, while transabdominal phase of the descent appears to be largely similar, scrotal phase differs due to their distinct scrotum positions. Our cell-labeling analyses and dynamic expression of Gsc1 reveal extensive cell/tissue rearrangements in murine scrotal development. In contrast, Gsc1 is not expressed in the developing genitalia and scrotal primordium of the opossum. Conclusion: Our results suggest recruitment of new regulatory pathways for the scrotum development and the scrotal phase of the testis descent during the evolution of eutherian mammals.
Use of a Liaison-Mediated Referral Strategy and Participation in Cardiac Rehabilitation After Percutaneous Coronary Intervention
Authors: Mansour Alexandra I. , Seth Milan , Thompson Michael P. , Casey Mary , Keteyian Steven J. , Smith Frank A. , Gurm Hitinder S. , Sukul Devraj
Published: October 2024

BACKGROUND:

Cardiac rehabilitation (CR) improves outcomes following percutaneous coronary intervention (PCI) but remains underutilized. A liaison-mediated referral (LMR), where a health care professional explains CR’s benefits, addresses barriers to participation, and places a referral before discharge, may promote CR use. Our objective was to assess the impact of an LMR on CR participation after PCI.

METHODS:

This was a retrospective study of patients who underwent PCI across 48 hospitals in Michigan between January 2021 and April 2022 and referred to CR before discharge. Clinical registry data were linked to administrative claims to identify the primary outcome, CR participation, defined as ≥1 CR session within 90 days of discharge. Bayesian hierarchical logistic regression was used to compare CR participation between patients with and without an LMR. For the secondary outcome, frailty proportional hazard modeling compared days elapsed between discharge and first CR session between liaison cohorts.

RESULTS:

Among 9023 patients referred to CR after PCI, 4323 (47.9%) underwent an LMR (mean age, 69.3 [SD=11] years; 68.3% male) and 3390 (36.7%) attended ≥1 CR session within 90 days of discharge. The LMR cohort had a higher unadjusted CR participation rate (43.1% [95% CI, 41.5%–44.6%] versus 32.4% [95% CI, 31.1%–33.8%];
P
<0.001), a higher adjusted odds ratio of attending ≥1 CR session (adjusted odds ratio, 1.21; 95% credible interval, 1.07–1.38), and a shorter delay in attending the first CR session compared with the non-LMR cohort (28 [interquartile range, 19–42] versus 33 [interquartile range, 21–47] days;
P
<0.001).

CONCLUSIONS:

An LMR was associated with higher odds of CR participation and may mitigate delays in CR enrollment. This referral strategy may improve CR participation and patient outcomes after PCI.
Design and Making Things Better: Relating the Pragmatism of John Dewey and Richard McKeon in Design Inquiry
Authors: Dixon Brian , Kaszynska Patrycja
Published: October 2024

This article proposes a model of social design inquiry directed toward shaping shared societal goals. Drawing on Dewey and McKeon, the approach is based on means-end evaluation and communication in plurality. This presents a response to the double challenge of dealing with conflicting aspirations for the future and the current need to balance differences in perspectives. The social design inquiry model provides the basis for meliorism in design insofar as it offers a way of working through these challenges by making use of imagination and deliberation.
Chinese Latinos and an Imagined Latin America: Transpacific Family, Identity, Culture, and Memory in Hong Kong, Macau, and Southern China
Authors: Schiavone Camacho Julia María
Published: October 2024

Based on oral histories and archival research in Hong Kong, Macau, and Guangzhou, this article focuses on identity and cultural formation among the descendants of overseas Chinese men and Latin American women. Some of the children and grandchildren of Chinese men and their wives in the diaspora have adopted Latin American identities even when they have never been to the region. While Chinese Latinos have created hybrid linguistic, cultural, and religious expressions, notions of Latin America have been central. Considering the myriad ways people have taken up Latin Americanness and integrated it into their mixed identities in Macau, Hong Kong, and southern China, this work explores what these experiences can tell us about the Chinese diaspora, return overseas migration, and the idea of “Latin America,” showing how Chinese Latino transnational families add to and complicate our understanding of the Latin American Chinese diaspora as well as southern China as a borderlands and contact zone.
Agency and Creativity in Exclusionist North America: Chinese Overseas Student Writings of Chen Hengzhe and Xie Fuya (1919–1926)
Authors: Lau Jennifer Junwa
Published: October 2024

Already on American soil, many Chinese student travelers sought to use their time to explore and turn their experiences into published works and travelogues. As a result, these routes and the writings that accompany them demonstrate a spectrum of Chinese experiences in North America during the Exclusion Era. The Chinese narrators in the writings of elite overseas Chinese students Chen Hengzhe (陈衡哲; 1890–1976) and Xie Fuya (谢扶雅; 1892–1991) carve a minor subjectivity through prose and poetry respectively that contributes to critical global history. Their voices are a creative vocalization of overcoming legal restraints placed on ethnic Chinese in textual representation that goes beyond narratives of oppression and resistance. The archives present an interesting and important perspective on Chinese raced bodies in twentieth-century North America.
“Isaiah” Revisited: the Civil Religion of Lim Boon Keng, 1893–1905 1893–1905
Authors: Dennerline Jerry
Published: October 2024

This article offers a new perspective on the Straits Chinese public intellectual Lim Boon Keng (1869–1957) in historical context. Rather than analyze Lim’s relative Chineseness, it explores the development of his argument that a new civil religion was necessary for citizenship in the post-Enlightenment world before the rise of reform and revolution in China. It introduces the positions and the rhetoric of key protagonists in local debates in Singapore over governance, education, and religion, and analyzes the influence of global developments such as the expansion of Methodist mission schools, the American Student Volunteer Movement, James Legge’s translations of Confucian classics, and the first World’s Parliament of Religions in 1893. I argue that Lim, who wrote as “Isaiah” in 1896 to oppose proselytizing in publicly supported schools while courting his Chinese Christian bride, may be understood as engaging the world as a modern world citizen.
Absolute Intercalibration of Spaceborne Microwave Radiometers
Authors: Wentz Katherine , Meissner Thomas , Wentz Frank , Manaster Andrew
Published: October 2024

Absolute calibration of spaceborne microwave radiometer observations consists of accurate determination of antenna cold space spillover, cross-polarization contamination, and nonlinearity coefficients of the receivers. We deem the GMI sensor to be the most accurate calibrated spaceborne microwave radiometer due to its unique calibration design features and its carefully planned orbit maneuvers. We demonstrate how to transfer the GMI calibration to other spaceborne radiometers, whose operations have sufficient time overlap with GMI. Specifically, we show results for WindSat and AMSR2. The sensor intercalibration is based on brightness temperature matchups between GMI and the other instruments over both open ocean and rainforest scenes. To assess the calibration accuracy, we compare the intercalibrated brightness temperatures with radiative transfer model calculations. In addition, we provide in situ validation results for wind speed and water vapor retrievals from the intercalibrated sensors. The intercalibration methodology allows for the creation of a multidecadal climate data record from passive microwave satellite observations.

Significance Statement

Creating a long-term climate data record of satellite observations of ocean winds, water vapor, and other variables requires careful and accurate calibration of the various sensors that are used. In particular, it is important to achieve the best possible consistency between the measurements from all the different instruments. This is a challenging task as the configuration and accuracy of these instruments can differ widely. The purpose of our paper is to demonstrate and validate the basic methodology for performing this intercalibration. The backbone of our method is data observed by a well-calibrated sensor that measures the passive microwave emission from Earth’s surface and atmosphere. We show how to transfer its calibration standard to other sensors.
Design and implementation of resilient controllers for uncertain quadruple tank systems: A nonlinear approach
Authors: Hashim Zahraa Sabah , Mahdi Ali Jafer , Ahmed Mahmood Anees , AL-Salih Asaad Abdul Malik Madhloom , Jawad Anwar Ja’afar Mohamad , Azar Ahmad Taher , Ibraheem Ibraheem Kasim , Hassan Hussein F. , Najm Aws Abdulsalam , Zalzala Ali Mahdi
Published: October 2024

A quadruple tank system using a new anti-disturbance technique called Modified Active Disturbance Rejection Control (MADRC) is introduced in this paper, along with a detailed examination of its design and hardware (H/W) implementation. To maintain the water levels in the quadruple system at predefined targets while minimizing the impact of external disturbances, the proposed scheme employs two advanced nonlinear controllers, enhanced tracking differentiator schemes, and newly developed nonlinear extended state observers (NNLESO). The proposed modified ADRC method outperforms the alternatives, according to the experimental data. With an improved ability to reject disturbances, the STC-ADRC approach reduced the output response oscillation to 3.33% of the equilibrium value. The NLPD-ADRC method, on the other hand, effectively managed system dynamics under disturbance conditions, as evidenced by a 4.666% oscillation. Additionally, disturbances had a significant impact on the S-fal-ADRC scheme, highlighting how distinct the proposed control mechanisms were in terms of performance. This work represents a significant advancement in the control of interconnected non-linear quadruple tank systems and proves that the MADRC method is effective in enhancing system stability and disturbance attenuation.
Crafting Convict Criminologists: An Invitation to Join Us in Prison
Authors: Boyce Benjamin , Carlock Jacob M.
Published: October 2024

As the second age of prison education begins to take shape with the reintroduction of Pell Grants to incarcerated people across the United States, there is a need for both effective teachers and effective teaching techniques. As previously and currently incarcerated educators, we offer a brief overview of imposter syndrome in prison while mapping a pathway through the use of communication for overcoming obstacles to education present in correctional settings. We end with a call for educators both inside and outside of prison to expand and pilot in-prison educational programs.
AUV SLAM method based on SO-CFAR and ADT feature extraction
Authors: Mu Xiaokai , Chen Haiyang , Wang Jiahao , Qin Hongde , Zhu Zhongben
Published: October 2024

Due to the exceptional detection capabilities, the forward-looking sonar could be adopted in simultaneous localization and mapping (SLAM) for autonomous underwater vehicle (AUVs). This paper primarily investigates the application of the factor graph optimization SLAM algorithm based on feature maps in AUV. It achieves this by combining the smallest of constant false alarm rate (SO-CFAR) and adaptive threshold (ADT) to filter noise from the forward-looking sonar and extract feature point clouds. Furthermore, a weighted iterative closest point (WICP) algorithm is employed for feature point registration, which is extracted from the sonar image. The experimental result based on field data demonstrates that the proposed method, with an 8.52% improvement in root mean square error (RMSE) compared with dead reckoning (DR).
Meta-Analytic Evidence That Message Fatigue is Associated With Unintended Persuasive Outcomes
Authors: Keating David M. , Skurka Chris
Published: October 2024

Message fatigue is a state in which people believe they have received too many similar messages conveying redundant information and feel a sense of exhaustion and boredom with those messages. A growing body of work suggests message fatigue inhibits persuasion, and a meta-analytic review can help to evaluate the strength and direction of the relationship between message fatigue and persuasive outcomes, explore potential moderators of that relationship, and shed light on productive paths forward. Our results indicated that, on average, increased message fatigue is associated with unintended outcomes such as increased endorsement of message-inconsistent beliefs and reduced intention to enact healthy behaviors ( r = −.25, k = 18, N = 24,236). Substantial heterogeneity was observed and, in general, left unexplained by our coded moderators. We speculate about the drivers of the observed heterogeneity and reflect on paths forward in this area of research.
Investigating thermal conduction dynamics in ternary Carreau–Yasuda nanofluids under convective boundary conditions and exponential heat source/sink effects
Authors: Jubair Sidra , Ali Bilal , Mahmood Zafar , Rafique Khadija , Kumar Abhinav , Emam Walid
Published: October 2024

The analysis of the Carreau–Yasuda nanofluid (CYNF) across a stretching surface has practical applications in several fields, such as heat exchange, engineering, and material science. Scholars may discover novel perspectives for increasing heat transfer performance, establishing advanced materials, and enhancing the efficiency of multiple engineering systems by studying the behavior of CYNF in this particular instance. The energy transfer through trihybrid CYNF flow with the effect of magnetic dipole across a stretching sheet is examined in the present study. The ternary hybrid nanofluid (THNF) has been prepared by the addition of ternary nanoparticles (NPs) in the water (50%) and ethylene glycol (50%). Titanium dioxide (TiO2), silicon dioxide (SiO2), and aluminum oxide (Al2O3) are used in base fluid. The fluid velocity and heat transfer are examined under the impact of Darcy–Forchheimer, chemical reaction, convective condition, activation energy, and exponential heat source. The fluid flow has been stated in form of velocity, energy, and concentration equations. The set of modeled equations is simplified to non-dimensional form of ordinary differential equations (ODEs) by using similarity substitutions. Numerically, the system of lowest order ODEs is calculated through the parametric continuation method. It has been noticed that the temperature field augments against the variation of viscous dissipation and heat source term. Furthermore, the magnetic dipole has significant impact to enhance the thermal curve of THNF whereas falloffs the velocity profile. It can be noticed that the energy propagation rate enhances with the rising numbers of ternary NPs, from 1.22% to 5.98% (nanofluid), 2.30% to 9.61% (hybrid nanofluid), and 3.23% to 11.12% (trihybrid nanofluid).
The Queer Clubhouse? Bar culture, sports media, and LGBTQ+ communities
Authors: Brody Evan
Published: October 2024

In the following article I analyze sports bars for Lesbian, Gay, Bisexual, Transgender, and Queer (LGBTQ+) communities via a combination of semi-structured interviews, field studies, and archival research. In particular, I examine how sports and non-normative sexual and gender identities influence, and are influenced by, media “in situ.” I also seek to better understand how LGBTQ+ sports cultures are constructed by the owners of these bars, by media technologies and rhythms, and by the patrons themselves. Within this approach I address how media and space overlap and inform one another, especially in relation to social and cultural imperatives, and I unpack how these interactions shape particular LGBTQ+ sports spaces. Guided by queer methodological and analytical approaches, I demonstrate how LGBTQ+ sports bars vary in material, contextual, and historical ways and how they are often influenced by competing concerns related to queer(ed) community and normative sports (media). Ultimately, I contend that to understand these spaces as built environments transformed by, and transforming of, LGBTQ+ communities, we must see them, as with most places of LGBTQ+ commerciality, as arenas of both queer potentiality and normalized inequality.
Do Income and Capital Influence Household Solar Panel Investment? A Meta-regression
Authors: Best Rohan , Marrone Mauricio , Linnenluecke Martina
Published: October 2024

There is considerable variation in research explaining household solar-panel investment, leading to mixed evidence regarding influences of income and capital. We provide analysis aiding interpretation of economic influences on solar-panel uptake in other studies. We conduct a meta-regression using 234 papers to provide analytical insights focusing on economic influences on solar-panel investment. We find that the research approach and context explain a range of income influences. More specifically, studies using household-level data are less likely to find negative income impacts compared to studies using aggregate data. Developing-country studies have been less likely to include income; but when income is included, developing-country studies have been more likely to find a significant link from income to solar-panel uptake. Capital (e.g., asset) impacts are nearly always positive and significant when included, but only 22 percent of analyzed studies included a relevant variable. Our concluding policy discussion suggests greater focus on assets for means testing.

JEL Classification: D10, Q40, Q48, Q50
Building power from below: Dispatches and lessons from movement building in a postindustrial city in Northern New Jersey in the United States
Authors: Ygarza George
Published: October 2024

Known locally as Silk City, the city of Paterson, New Jersey, has been deeply impacted by neoliberalism and global capitalism. Interlocking systems of globalization have impacted housing conditions and increased the criminalization of the poor, all of which have ultimately driven down living standards. As the city began its revitalization efforts at the turn of the twenty-first century, community members soon began to debate the costs and benefits of these new programs. One of the organisations helping to facilitate consciousness raising is Black Lives Matter Paterson and various autonomous sub-committees including the Political Education committee. Part auto-ethnographic and part analytical, this article describes the process of building a movement at the same time it confronts activist-intellectual identities that are often held in tension. Written as an auto-ethnography, this article synthesizes the lessons drawn from a ‘turn back’ to community and grassroot organising. Rather than foreground theory in community organising efforts, this article centres praxis as it reflects on the coordination of two peoples’ assemblies in a post-industrial city in Northern New Jersey in the United States. Inverting the conventional pathways of organising by starting with questions rather than answers, the article relies on an inductive and grounded approach. The second part speaks of the praxis taken up to build up a peoples’ assembly. Altogether, an organic process of community organising is made visible through the lessons learned from community engagements.
early specification or the development of the whole personality: experience from a Hungarian counsellor
Authors: Herskovits Maria
Published: October 2024

Counselling for gifted in Hungary has grown out of our vocational guidance practices and it is based on its rich theoretical and methodological approaches. Principally our work fits into the framework of Renzulli’s model.

Ever since ECHA-Hungary (1988) and the Hungarian Association for Gifted Children (1989) were founded there has been a strong pressure on a few experts to start a voluntary service for parents.

In the last two years, 34 families have turned to us for help. In most of the cases the childen’s ages range between 5-9 years so in this presentation only their problems will be discussed.

1. Parents are ready to promote the development of their children’s obvious high ability, but are not aware of the possibilities.

2. What sort of school, or class should a child attend who has the mastery of the 3 R’s at the age of 6?

3. Parents think their children should specialize at a very early age so that their talent is not wasted, on the other hand they feel the child should be left “in peace” to let his wide range of interests develop.

4. Parents are not able to cope with a great variety of problems; the child is stubborn, self-willed, impulsive, finds hardly any friends, the teachers make complaints etc.

Testing of the children happens only if it is absolutely necessary. Counselling means mainly giving advice to parents. They are uncertain how to handle “excellence” and “difference” due to the 45 years of forced attitude to egalitarianism and the "Prussian" tradition in our education.
Hypoalbuminemia is a predictor of mortality in patients with cardiogenic shock requiring veno-arterial extracorporeal membrane oxygenation
Authors: Raja Katherine M. , Plazak Michael , Rabin Joseph , Shah Aakash , Grabenstein Ilana , Rao Appajosula , Bathula Allison , Stachnick Stephen , Massey Howard T. , Zapata David , Taylor Bradley , Grazioli Alison
Published: October 2024

Introduction

Hypoalbuminemia is predictive of mortality in critically ill patients, especially those with cardiac etiologies of illness. The objective of this study was to determine the association of albumin level pre-cannulation for veno-arterial (V-A) extracorporeal membrane oxygenation (ECMO) and important clinical hospital outcomes.

Methods

This was a retrospective, observational cohort study of albumin levels in patients with cardiogenic shock requiring V-A ECMO between December 2015 and August 2021 in a single, high-volume ECMO center. The primary outcome was in-hospital mortality.

Results

Of 434 patients assessed, 318 were included. The overall mean pre-ECMO albumin was 3 ± 0.8 g/dL and mean albumin at 72 hours post-cannulation was 2.7 ± 0.5 g/dL. For patients with pre-ECMO albumin ≤3 g/dL vs. >3 g/dL, in-hospital mortality was 44.9% vs. 27.5%, respectively ( p = .002). In multivariable logistic regression analysis, higher albumin (per 1 g/dL increase) at time of V-A ECMO initiation was associated with decreased odds of in-hospital mortality (OR, 0.68; 95% CI, 0.48-0.96; p = .03). Patients with a pre-ECMO albumin ≤3 g/dL required significantly more platelet transfusions and had higher incidence of gastrointestinal bleeding during V-A ECMO support (both p < .05).

Conclusions

Hypoalbuminemia at time of cannulation is significantly associated with in-hospital mortality and ECMO-related complications including platelet transfusion and gastrointestinal bleeding. Albumin levels at the time of consideration of V-A ECMO may serve as a key prognostic indicator and may assist in effective decision-making regarding this invasive and costly resource.
TriVAD: Successful use of Impella 5.5 and Protek Duo CentriMag RVAD following Heartware HVAD thrombosis as a bridge to heart transplant
Authors: Chiou Edward , Lewis Connor , Creel-Bulos Christina , Miller Casey F. , Chan Joshua L. , Daneshmand Mani A.
Published: October 2024

Introduction

Pump thrombosis remains a feared complication following placement of durable left ventricular assist devices (LVAD) and can be particularly detrimental to individuals being bridged to heart transplantation. Complications associated with this malfunction not only increase morbidity related to right heart failure, hemolysis, and other organ failure, but may ultimately jeopardize a patient’s heart transplant candidacy. Additionally, reoperation for durable ventricular device replacement not only poses additional surgical risks to patients but can potentially complicate or even prohibit transplantation in the future.

Case report

This case report describes a novel configuration of temporary, groin-free, percutaneously-deployed biventricular mechanical circulatory devices to support a patient with biventricular failure due to partial LVAD thrombosis.

Discussion/conclusion

The use of less invasive mechanical support measures, such as the approach described here, may help patients achieve adequate hemodynamic support while allowing them to remain ambulatory and facilitate successful bridging to heart transplantation.
Effects of urbanization on river morphology in a Mediterranean coastal city (Genova, Italy)
Authors: Mandarino Andrea , Brandolini Pierluigi , Terrone Martino , Faccini Francesco
Published: October 2024

From the geomorphological point of view, urbanization changes fluvial systems more drastically than any other single human activity. Its impact on rivers is of interest as it results in serious issues concerning geomorphic instability, ecosystem service reduction, and geo-hydrological risk increase. The present study provides a quantitative and qualitative assessment of landscape changes driven by urbanization, which occurred from the mid-19th century to the present day along the lower reaches of the Bisagno and Polcevera rivers and their tributaries in the Mediterranean coastal city of Genova (NW Italy). The bankfull channel morphological adjustments, the minor hydrographic network disappearance, the land use and land cover changes, and the current physical accessibility of river margins were investigated. This work is based on collection and review of historical data, photograph interpretation, GIS analysis, and field surveys. Urbanization essentially occurred between the mid-19th century and the late 1930s. The bankfull channel of the Bisagno and Polcevera rivers experienced large narrowing associated with widespread establishment of channelization structures. The minor hydrographic network essentially disappeared underground. After the 1930s, further minor anthropogenic interventions were implemented to accommodate urban expansion and consolidate channelization works; however, the overall geomorphological setting remained unchanged. The geomorphological evolution of the Bisagno and Polcevera rivers followed three different phases associated with the urban expansion process. Nowadays, the study area is completely urbanized, the fluvial stems flowing through the valley floor are totally disconnected from their adjacent areas, the main rivers show a relevant geomorphological stability induced by anthropogenic pressures, and the accessibility of river margins for people is rather limited. The outcomes from this study represent an essential knowledge base for technicians and policymakers to plan urban development and inform effective and sustainable management measures. Moreover, they provide insights into the medium- and short-term morphological evolution of urban rivers.
Multiport event-triggered finite-time PID control for underactuated unmanned surface vessels under cyber attacks
Authors: Meng Xiangfei , Zhang Guichen , Han Bing , Liu Xuanming
Published: October 2024

This paper studies the network security control problem of underactuated unmanned surface vessels (USVs) affected by injection and deception attacks and proposes a novel finite-time PID (FT-PID) control method. To solve the problem of lateral drive mismatch of underactuated vessels, the heading harmonized dynamic control method (HHDCM) is used to utilize the characteristics of the arctangent function to closely combine the motion control with the geometric direction. Then, all uncertain dynamics in the system are converted into the form of neural single-parameter learning, and the kinematic channel and dynamics channel control mechanisms are given the function of high-speed self-adjusting control gain by constructing a dynamic error integrated variable (DEIV). To reduce the network communication load and improve data security, a novel event-triggered control (ETC) approach is constructed by introducing a variable that describes the internal characteristics of the measurement error. Stability analysis based on Lyapunov theory shows that the proposed FT-PID control mechanism can ensure that all signals in the underactuated USV closed-loop system are bounded. Finally, the effectiveness of the control scheme is verified through simulation.