bluuebunny/crossref_metadata_2025 huggingface dataset:
Association between pulmonary vein stenosis and necrotizing enterocolitis or gastrointestinal pathology
Authors: Duchon Jennifer , Farkouh-Karoleski Christiana , Bailey Dominique D. , Krishnan Usha S.
Published: February 2023

Objective:

Pulmonary vein stenosis (PVS) is an emerging cause of pulmonary hypertension in preterm infants. It is an often lethal condition with poor long.term prognosis and high mortality. Previous work suggests an association between necrotizing enterocolitis (NEC) and PVS, supporting a possible role for inflammatory processes due to gastrointestinal (GI) pathology as an associated risk factor for PVS.

Study Description:

We performed a matched case–control study where infants with PVS were matched for gestational age with infants without PVS. Hospital records were reviewed for prior history of NEC or other gut pathology.

Results:

Twenty-four PVS patients were matched with 68 controls; 63% of patients (15/24) had prior GI pathology as opposed to 19% (13/68) of controls. The GI pathology group had a significantly higher growth restriction and C-reactive protein. The mean gradient across the pulmonary veins was higher in the gut pathology group versus controls, as was mortality (29% vs. 9%).

Conclusions:

The previously described association between PVS and intestinal pathology was further strengthened by this study. The presence of GI pathology should lead to early surveillance and intervention for PVS.
Coxsackie B viral infection presenting with hemorrhagic pericardial effusion and pleural effusion
Authors: Maram Krishna Prasad , Kudumula Vikram , Paturi Venkata Rama Rao
Published: February 2023

We report an 11-year-old female child presenting with hemorrhagic pericardial effusion causing cardiac tamponade along with moderate left ventricular dysfunction, who screened positive for Coxsackie B infection in the setting of cough, shortness of breath, and chest pain. She needed emergency pericardiocentesis. She also had massive bilateral hemorrhagic pleural effusions requiring bilateral chest drains placement. With a presumed diagnosis of acute myopericarditis, she was treated with steroids and ibuprofen. She made a full recovery without any further recurrence of pericardial or pleural effusion.
Thrombosis of aneurysmal pulmonary arteries in patent ductus arteriosus with Eisenmenger syndrome
Authors: Bhattacharya Deepanjan , Sasikumar Deepa , Kurup KN Harikrishnan , Anoop Ayyappan , Gaddamedi Sravan Kumar
Published: February 2023

A 45-year-old lady with patent ductus arteriosus with Eisenmenger's syndrome had presented with hemoptysis. Computed tomography revealed aneurysmally dilated pulmonary arteries with a large calcified organized thrombus.
Isolated ostial left main coronary artery stenosis causing ischemic cardiomyopathy in a child with bicuspid aortic valve
Authors: Chohan Amad , Abraham Carol J. , Ward Kent , Ponniah Kumar , Salkini Anas , Burkhart Harold M. , Mir Arshid
Published: February 2023

Bicuspid aortic valve (BAV) is the most common congenital cardiac defect, commonly associated with valve dysfunction and coarctation of aorta. Rarely, BAV can be associated with abnormalities of the coronary arteries, the most common of which are ectopic coronary origins. In this report, we present a case of a 2-year-old child with BAV, without coexisting supravalvular aortic stenosis, who was found to have a left main coronary ostio-proximal stenosis, leading to ischemic cardiomyopathy and congestive heart failure.
Estimating Center of Rotation of Single-Photon Emission Computerized Tomography Projection Images Using MATLAB for Standardization and Calibration
Authors: Pandey Anil Kumar , Chaudhary Jagrati , Kaur Gagandeep , Yadav Priya , Sharma Param Dev , Patel Chetan , Kumar Rakesh
Published: February 2023

Objective:

The objective of the study was to develop a Personal Computer (PC) based tool to estimate the center of rotation (COR) offsets from COR projection datasets using methods mentioned in IAEA-TECDOC-602.

Materials and Methods:

Twenty-four COR studies were acquired on Discovery NM 630 Dual head gamma camera fitted with parallel hole collimator, and COR offsets were estimated with the software available at the terminal for processing a COR study. These COR projection images were exported in DICOM. A MATLAB script (software program) was written to estimate COR offset using Method A (using opposite pair of projections) and Method B (using curve fitting method) as mentioned in IAEA-TECDOC-602. Our program read the COR study (in DICOM) and estimated COR offsets using Method A and Method B. The accuracy of the program was verified using simulated projection dataset of a point source object acquired at 6° interval in the range of 0°–360° angle. Bland Altman plot was used for analyzing the agreement between the COR offsets estimated using (1) Method A and Method B mentioned in IAEA-TECDOC-602, and (2) Our program and vendor program available at Discovery NM 630 acquisition terminal.

Results:

On simulated data, offset from center of gravity (COG) in X direction (COGX) and COG in Y direction (COGY) estimated using Method A was constant (same) at each pair of angles while using Method B, it was found to be in the range (−2 × 10−10, 1 × 10−10) which is negligible. Most of the differences (23 out of 24) between the result of Method A and Method B, and between the results of our program and vendor program was found to be within 95% confidence interval (mean ± 1.96 standard deviation).

Conclusions:

Our PC-based tool to estimate COR offsets from COR projection datasets using methods mentioned in IAEA-TECDOC-602 was found to be accurate and provides results in agreement with vendor's program. It can be used as an independent tool to estimate COR offset for standardization and calibration purposes.
Imaging Acute Myocarditis with 68Ga-DOTANOC PET/CT
Authors: Jaleel Jasim , Patel Chetan D , Chandra Khangembam Bangkim , Ramakrishnan Sivasubramanian , Seth Sandeep
Published: February 2023

Somatostatin receptor (SSTR) imaging is a useful method in the diagnosis of acute myocarditis. We present a case of a 54-year-old male with a clinical diagnosis of acute myocarditis in whom, 68Ga-DOTANOC positron emission tomography/computed tomography PET/CT showed diffuse left ventricular myocardial uptake. SSTR imaging can act as a surrogate marker of active inflammation. SSTR imaging is useful in deciding site of biopsy, assessing response to therapy and for prognostication.
Evaluation of New Tracers in the Identification of Sentinel Lymph Node in Patients with Early Breast Cancer
Authors: Srivastava Anurag , Goyal Amit , Seenu Vuthaluru , Kumar Rakesh
Published: February 2023

Purpose:

Sentinel node mapping is the standard of care for evaluation of axilla for women with early node negative breast cancer. Validation of a new tracer for sentinel node biopsy requires full axillary lymph node dissection to establish its performance indicators. This exposes about 70% of women to unnecessary axillary dissection with its attendant morbidity.

Aims and Objective:

To investigate the predictive value of identification of sentinel lymph nodes by a tracer for knowing its sensitivity and false-negative rates (FNR).

Methods:

A linear regression on data from a network meta-analysis was carried out, and the correlation between identification and sensitivity and its predictive value were ascertained.

Results:

A strong linear relationship was observed between identification and sensitivity of sentinel node biopsy (correlation coefficient r = 0.97). The sensitivity and false negativity can be predicted by the identification rate. An identification rate of 93% corresponds to sensitivity = 90.51% and a FNR = 9.49%. The current literature on newer tracers has been succinctly reviewed.

Conclusion:

The linear regression demonstrated a very high predictive value of identification rate for ascertaining the sensitivity and FNRs of sentinel node biopsy. A new tracer for sentinel node biopsy can be introduced in clinical practice, if it achieves an identification rate of 93% or more.
Tobacco Cessation is a Challenge During COVID-19 Pandemic
Authors: Nagi Ravleen , Reddy Sujatha S. , Rakesh N. , Vyas Tarun
Published: February 2023

Introduction:

COVID-19 is a global health crisis experienced ever, caused by novel severe acute respiratory syndrome coronavirus-2 (SARS CoV -2); unfortunately, this pandemic is still progressing, affecting over millions of people worldwide. Evidences have revealed that psychological stress experienced during pandemic is making tobacco users more addictive, therefore to prevent especially youth from harmful effects of tobacco, tobacco cessation is the need of the hour.

Aim:

The aim of this systematic review was to compile evidence-based studies pertaining to tobacco use during COVID-19 pandemic and highlighting the challenges incurred towards successful quit attempts by the tobacco user.

Materials and Method:

Computerized literature search was performed from December 2019 till June 2020 to select eligible articles from the following databases: PUBMED [MEDLINE], SCOPUS, SCIENCE DIRECT, and COCHRANE DATABASE using specific keywords. The search was limited to articles published as full text in English, which were screened by two reviewers for eligibility.

Results:

Six studies satisfied our inclusion criteria. Two studies found that tobacco users have achieved successful quitting during lockdown period, and contrary to this three studies suggested that users have become more addictive to smoking due to psychological stress experienced during pandemic. One study suggested current smokers to be higher risk of acquisition of severe disease.

Conclusion:

Oral physicians should extend extra support to tobacco users to quit by brief or moderate interventions by means of telephonic consultation or video conferencing during this pandemic. In future more studies should be conducted to understand the effect of pandemic on tobacco use pattern.
Novel Physiotherapy Appliance in the Management of Oral Submucous Fibrosis
Authors: Ramachandra Reddy G. V. , Shinde Christopher V. , Khare Pooja
Published: February 2023

Background:

Limitation of mouth opening is one of the most common sequelae of various pathological processes leading to compromised nutritional state in addition to physical and psychological disabilities. OSMF is one such condition with severe trismus, debilitment, and an increased risk for malignancy.

Methodology:

This prospective clinical study describes the fabrication and use of a new functional appliance known as Shekar's appliance. Three OSMF patients were selected and enrolled in the study and appliance was fabricated. Assisted supervised oral physiotherapy session was performed with the appliance.

Result:

Excellent improvement in mouth opening was observed in all the three patients treated with the appliance. The mean increase in mouth opening was recorded as 8.6 mm.

Conclusion:

Oral physiotherapy induces tissue remodeling in OSMF to increase mouth opening.
Central Giant Cell Granuloma in a 10-Year-Old Pediatric Patient - A Rare Entity in Posterior Mandible with CBCT Findings
Authors: Jose Divya , Murugan Kandasamy , Sathiasekar Anisha Cynthia , Kumar Dhineksh
Published: February 2023

Central giant cell granuloma (CGCG) of bone constitutes about 7% of all benign lesions of the jawbones. CGCG, as described by Jaffe in 1953, is an idiopathic non-neoplastic proliferative lesion. The mandible anterior to the first molar is the frequently affected site, and has a tendency to cross the midline. Though CGCG is a benign reactive osseous lesion, it has been classified into two types based on its clinic-radiologic features into a slow growing asymptomatic, nonaggressive lesion, and an aggressive type encountered in younger patients which is painful and grows rapidly into a large size, perforating the cortex causing root resorption, and has a tendency to recur. We report a rare case of aggressive CGCG with massive destruction in molar region and angle of mandible.
Relación entre Emociones y Recuerdo en Campañas Publicitarias de Servicio Público. Una Aproximación desde la Neurociencia
Authors: Baraybar Fernández Antonio , Baños Gonzalez Miguel , Rajas Fernández Mario
Published: February 2023

Introducción: Los anuncios de servicio público son una estrategia valiosa para modificar actitudes y comportamientos relacionados con temas de interés social. Estos mensajes persiguen, frecuentemente, una respuesta emocional en el público por lo que las técnicas de neurociencia se muestran como herramientas útiles para comprender mejor el comportamiento de los públicos, reducir la incertidumbre en la toma de decisiones y desarrollar acciones más eficaces. Metodología: Este estudio tiene como objetivo conocer la relación que tienen las emociones inducidas en los mensajes publicitarios audiovisuales de servicio público y el recuerdo en una muestra de individuos, segmentada por sexo, expuestos a anuncios de servicio público. En el experimento se ha registrado la actividad eléctrica del cerebro, la frecuencia cardíaca y la respuesta electrodérmica. El recuerdo se ha medio mediante un test aplicado a los sujetos. Resultados: Con los datos obtenidos se ha se ha calculado el Índice Emocional y el Índice Apetitivo/Aversivo para determinar la respuesta emocional y la motivación, positiva o negativa, hacia los estímulos. También se han obtenido datos del recuerdo de los sujetos, espontáneo y sugerido, así como del significado emocional subjetivo que los estímulos han provocado en los sujetos Conclusiones: Con estos datos se demuestra la relación entre el estado emocional generado por los mensajes y su recuerdo; que existen diferencias, tanto en el Índice Emocional como en el Índice Apetitivo/Aversivo, entre hombres y mujeres; y se pone de manifiesto la importancia de tener en cuenta otros aspectos de la narración además de transmitir una emoción.
ADAPTIVE GOVERNANCE AND WATER SECURITY IN THE CONTEXT OF CLIMATE CHANGE IN THE SEMI-ARID
Authors: Dias Eric Mateus Soares , Pessoa Zoraide Souza , Teixeira Rylanneive Leonardo Pontes
Published: February 2023

The aim of this paper is to analyze whether the management of water resources in the state of RN meets the requirements of adaptive governance in order to enable adaptation processes to the possible impacts of climate change in semi-arid regions. To do so, the work follows the guidelines of a qualitative, exploratory and descriptive approach using a set of research instruments: bibliographic survey, case study, structured interviews and content analysis. The results show that the management of water resources in RN presents a series of challenges and obstacles to configure itself in a climate adaptive governance perspective. In summary, it is concluded that the management of water resources in the state of RN still does not meet the requirements of a robust adaptive governance capable of operating responses to the risks of climate change and ensuring water security. Keywords: Climate Change. Adaptation. Management of Water Resources. Sustainability. Brazilian Semi-arid.
REGULATION ECOSYSTEM SERVICES IN A WATERSHED IN THE SEM-IARID OF BRAZIL
Authors: Oliveira Paulo Jerônimo Lucena de , Guedes Jânio Fernandes , Costa Diógenes Felix da Silva
Published: February 2023

Human pressures on ecosystems from the use and suppression of vegetation cover cause negative actions on biodiversity, impacting nature and the ecosystem services provided by the same. The focus of this research is to evaluate the ability to provide Ecosystem Services in the Seridó River Basin (RN / PB). Modeling techniques were applied from USLE, in addition to vegetation and organic carbon indices. The results showed that the highest values ​​of NDVI are in areas of higher elevation and slope, and the lowest values ​​found in flat areas. Six classes of land use were identified, namely: Water bodies, urban area, Pasture and exposed rock, Caatinga Subarbustiva, Subarbórea and Arbórea. As a result, the areas of greatest relevance for providing Organic Carbon stock services are in the highest areas, with the areas with the greatest erosion control located in escarpment areas. Key words: Ecosystem Services; Modeling; Caatinga; Semiarid; Hydrographic basin.
The cultural adaptation of quantity judgment tasks in Ghanaian English and Akan
Authors: Mohr Susanne , Agyepong Dorothy
Published: February 2023

The phenomenon of mass and countability is multifaceted and has been controversially discussed in many disciplines. For linguistics, differences in the morphosyntactic marking of the distinction cross-linguistically, and its cross-cultural ontological-semantic conceptualization are particularly interesting. However, most studies into mass and countability have focused on (American) English, and, to some extent European and Asian languages. African languages and contexts have as yet been neglected by researchinto countability, and the methodological tools employed to study it do not account for the ambient cultural contexts. This paper presents the results of a quantity judgment task designed according to Barner and Snedeker’s (2005) experiment for American English speakers, conducted in Ghanaian English and Akan. The Ghanaian experiments reveal important concerns regarding the stimuli and their applicability, especially to Akan culture. Thus, inspired by other studies into the semantics of Akan, a new set of stimuli is suggested in order to investigate mass and countability contrastively in Ghanaian English and Akan. In this vein, they emphasize the insufficiency of translations with regard to (psycho)linguistic experiments and the importance of proper cultural adaptation.
Manger, Itsik (1901–1969)
Authors: Rozenfeld Anna
Published: February 2023

Itsik Manger was a prominent Yiddish poet, playwright, and prose writer – a ‘master tailor’ of the written word. He entered the field of Jewish literature as the ‘Duke of the Jewish Ballad’. Manger drew his inspiration from traditional troubadour poetry, recreating the past and interpreting it with modernist sensibilities. In his works he referred to folk poetry and adapted biblical themes, writing about the fate of the Jews in Eastern Europe.
Telles, Gonçalo Ribeiro (1922–)
Authors: Soeiro Diana
Published: February 2023

Gonçalo Ribeiro Telles (1922–), landscape architect and politician, was born in Lisbon, Portugal. In 1942 he attended the Instituto Superior de Agronomia da Universidade Técnica de Lisboa where he studied Agricultural Engineering. On graduating, he heard that a new free course was being offered by Francisco Caldeira Cabral (1908–92) on Landscape Architecture. As this was the first time that the subject had been made available in Portugal, a group of students decided to take the course, among them Ribeiro Telles. In 1951 he started working at Lisbon’s City Hall, first as an office boy and two years later as a landscape architect. The institution was receptive to such professionals because the President’s son, António Viana Barreto (1924–2012), was one of them, and hence, President Álvaro Salvação Barreto (1890–1975), having previously hired Manuel Azevedo Coutinho, also hired Ribeiro Telles. He formed a team with Azevedo Coutinho, and together they started to promote urban green spaces in Lisbon.
Siza Vieira, Álvaro (1933–)
Authors: Soeiro Diana
Published: February 2023

The architect Álvaro Siza Vieira (1933–) was born in Porto, Portugal. He graduated from the University of Porto (now known as the Faculdade de Arquitectura, Universidade do Porto – FAUP) in 1955. While still a student in 1954 he built four houses in his home town, Matosinhos, where he opened his own private practice. Between 1955 and 1958 he collaborated with his former teacher, Fernando Távora (1923–2005). During the 1960s he designed and built a swimming pool project (Leça da Palmeira, Porto) that caught the attention of the public. He was invited to lecture at the university from 1966–69. In 1976 he returned to teaching and shortly afterwards, in 1979, the university was renamed the FAUP, following the establishment of democratic government after the end of dictatorship (1926–74) under Oliveira Salazar (1889–1970). The FAUP sought to instigate the principles of Modernism based on the architect’s individual character, i.e. not according to the prevailing Soft Portuguese style. Three individuals became identified with the new FAUP, known as the Porto School of Architecture: Távora, Siza Vieira, and one of his students, Eduardo Souto Moura (1952–; winner of the Pritzker Prize in 2011). In the new era of democracy that flourished in Portugal, in 1977 he planned 1,200 low-cost housing units in Évora, for the national housing association, the Serviço Ambulatório de Apoio Local.
Woodcut Novel
Authors: Fontenot Tyler
Published: February 2023

The novel in woodcuts or the wordless novel is an artistic and narrative medium that emerged during the first half of the 20th century. The first novel in woodcuts was 25 Images de la passion d’un homme [25 Images of a Man’s Passion], published in 1918 by the Flemish engraver Frans Masereel. Wordless novels rose to prominence in the 1920s, reaching a zenith of popularity in the 1930s that waned during the Second World War due to competition with sound film and anti-socialist censorship, especially in Nazi Germany and the United States. As the narrative is communicated in pictures rather than in words, novels in woodcuts are accessible to international audiences regardless of language or literacy. This universal comprehensibility helped to disseminate to an international audience the critical depictions of capitalism, modern alienation, and the industrial metropolitan space that run through many wordless novels. History has until recently largely forgotten the impact of the novel in woodcuts, but some of the first graphic novelists, like Art Spiegelman and Will Eisner, have acknowledged these early wordless novels as a major inspiration for the development of the graphic novel form.
Ward, Lynd (1905–1985)
Authors: Fontenot Tyler
Published: February 2023

Lynd Kendall Ward was an American artist best known for the six novels in woodcuts he created between 1929–37, though he was also an accomplished illustrator, painter, and author of over 100 children’s books. Ward was responsible for bringing the wordless novel to America beginning with his first work, Gods’ Man (1929), the first American novel in woodcuts and still perhaps the most famous work of the genre. Ward’s contributions to the form, style, and popularity of wordless novels in America and around the world are tremendous, although until recently Ward’s works have largely been neglected in both art history and literary scholarship. Recent critics and early graphic novelists who were inspired by Ward, however, have acknowledged the way in which Ward’s works consistently engaged with the central questions of American Modernism and anticipated the rise of contemporary graphic storytelling.
KuNgoni Centre of Culture and Art
Authors: Cubbon Alexandra
Published: February 2023

Founded in 1976 by Canadian White Father Claude Boucher, a Christian missionary, the KuNgoni Centre of Culture and Art is a non-profit organisation located in central Malawi. The centre, originally established to teach local artists new carving techniques, lies in close proximity to the Mua Mission, the oldest station of the Missionaries of Africa (the White Fathers) in Malawi, and its resources and exhibitions explore the cultures of three tribes of the Mua region: Chewa, Ngoni, and Yao. In particular, the KuNgoni Centre houses artifacts and oral histories of Gule Wamkulu, a secret society of the Chewa, who perform the gule wamizimu, or ‘dance of the spirits’. UNESCO named the gule wamizimu a ‘Masterpiece of the Oral and Intangible Heritage of Humanity’ in 2005.
The Relationship between Sodium Intake and Nutritional Status with Hypertension Incidence in the Work Area of the Alosika Health Center, Konawe Regency
Authors: Islawati Islawati , Abadi Ellyani , Dhesa Desiderius Bela
Published: February 2023

Abstract. Hypertension is a condition where blood pressure exceeds 140/90 mmHg. Hypertension can cause complications of cardiovascular diseases such as stroke, heart disease and diabetes mellitus. Hypertension at the Alosia Health Center in 2021 was 72 cases and increased in 2022 for the January-March period by 90 cases. The purpose of this study was to determine the relationship between sodium intake and nutritional status with the incidence of hypertension. Quantitative research design, cross sectional study approach. The sample is partly all patients registered at the Alosika Health Center, Konawe Regency in 2022 for the January-March 2022 period as many as 89 obtained by Simple Random Sampling. Data were analyzed using Chi-square test. The results of the study from 89 samples, the incidence of hypertension, most of them had hypertension (66.3%), then based on sodium intake, most were more (67.4%) and based on nutritional status most of 56 people (62.9%) nutritional status normal. Chi-Square test obtained p value 0.000 for the relationship of sodium intake with the incidence of hypertension and p value 0.001 for the relationship between nutritional status and the incidence of hypertension. The conclusion of this study is that there is a relationship between sodium intake and nutritional status with the incidence of hypertension in the work area of the Alosika Health Center, Konawe Regency.
Nurse's Experience While Caring for Covid-19 Patients at Kendari City Hospital in 2022
Authors: Sya Kasiman , Tahiruddin Tahiruddin , Umrana Siti
Published: February 2023

Abstract. The Coronavirus disease has caused fear and tension globally since the pandemic started. The increasing number of cases with high mortality is of course very stressful, especially for medical nurses who are at the forefront of dealing with cases of the world-scale Corona virus pandemic. The purpose for this research is to investigate the meeting of medical nurses while really focusing on Corona virus patients at Kendari City Hospital. The type of research used is phenomenological research. This research was carried out at the Kendari City Hospital in August 2022 involving 6 participants who used a purposive sampling technique. The triangulation used is data and research triangulation. The results of the study found that the theme of the nurse's experience in the ups and downs category showed that the nurse's care that was expressed was when wearing personal protective equipment, unable to meet with family for a very long time while the joy was that with this pandemic nurses gained new knowledge and experience.Furthermore, the category that causes stress is the problem of using PPE (personal protective equipment) due to difficulty breathing, overheating and dehydration, in the category of how to reduce anxiety, namely nurses by praying a lot and chatting with other nurses, in the category of how to adapt, namely by obeying SOPs to be protected from being infected with covid 19. Furthermore, the category of using PPE for nurses stated that they were less comfortable in using personal protective equipment, while in the category of expectations, nurses while caring for Covid-19 patients wanted the pandemic to end soon and the welfare of nurses to remain a priority as well as the hopes of other nurses so that all elements of the community still adhere to the appropriate health protocol. standard operating procedures (SOP). It was concluded that nurses gain new knowledge and experience. It is recommended to improve the quality of nurses when providing services during the Coronavirus pandemic, emphasizing the importance for nurses to receive clear and up-to-date information about best practices in nursing care, prevention and control of Coronavirus infection.
Comparison of Bedside Test Kits for Prediction of Preterm Delivery: Phosphorylated Insulin-like Growth Factor Binding Protein-1 (pIGFBP-1) Test and Fetal Fibronectin Test
Authors: Ting Hua-Sieng , Chin Pui-See , Yeo George SH , Kwek Kenneth
Published: February 2023

Objective: The objective of the study was to compare the effectiveness of bedside test kits for pIGFBP-1 and fetal fibronectin test in predicting preterm delivery. Materials and Methods: Patients presenting with symptoms of preterm labour between 24 and 34 weeks of gestation were recruited. Both pIGFBP-1 and fetal fibronectin bedside tests were performed. Managing obstetricians and patients were blinded to the pIGFBP-1 and fetal fibronectin results. Tocolysis and steroid therapy were administered to all the recruited patients. Outcome data were collected after delivery. Results: One hundred and eight patients were recruited into the study. Fourteen patients had to be excluded from the final analysis due to incomplete data and failure to meet inclusion criteria. Ninety-four patients had complete data for analysis. Among those with negative pIGFBP-1 and fetal fibronectin results, the median [±standard deviation (SD)] gestational age at delivery was 37.4 weeks (±2.8 weeks) and 37.4 weeks (±2.1 weeks), respectively. Among those with positive pIGFBP-1 and fetal fibronectin results, the median (±SD) gestational age at delivery was 32.9 weeks (±4.0 weeks) and 34.2 weeks (±4.2 weeks), respectively (P <0.001 for both pIGFBP-1 and fetal fibronectin). A positive result with either test was associated with a significantly reduced admission-to-delivery interval. The median admission-to-delivery interval was 2.8 weeks shorter in the group with positive pIGFBP-1 results compared to those with a negative pIGFBP-1 result (2.3 weeks compared with 5.1 weeks) (P <0.001). This is 1.8 weeks shorter in the group with positive fibronectin results, compared to those with a negative result (3.3 weeks compared with 5.1 weeks) (P = 0.002). Both pIGFBP-1 and fetal fibronectin tests have high negative predictive value (NPV) in predicting risk of delivery within 48 hours, 7, or 14 days (1.00; 0.92; 0.92 and 0.97; 0.89; 0.89, respectively). Conclusions: Both pIGFBP-1 and fetal fibronectin tests are effective adjuvant bedside test kits for the prediction of preterm delivery in patients presenting with signs or symptoms of preterm labour. pIGFBP-1 has the higher NPV of 1.00 in predicting risk of delivery within 48 hours. Keywords: Early delivery, Labour ward, Objective test
Cross-Cultural Adaptation and Validation of Singapore Malay and Tamil Versions of the EQ-5D
Authors: Wee Hwee-Lin , Loke Wai-Chong , Li Shu-Chuen , Fong Kok-Yong , Cheung Yin-Bun , Machin David , Luo Nan , Thumboo Julian
Published: February 2023

Introduction: The aims of this study were to cross-culturally adapt and evaluate the validity of the Singaporean Malay and Tamil versions of the EQ-5D.

Materials and Methods: The EQ5D was cross-culturally adapted and translated using an iterative process following standard guidelines. Consenting adult Malay- and Tamil-speaking subjects at a primary care facility in Singapore were interviewed using a questionnaire (including the EQ-5D, a single item assessing global health, the SF-8 and sociodemographic questions) in their respective language versions. Known-groups and convergent construct validity of the EQ-5D was investigated by testing 30 a priori hypotheses per language at attribute and overall levels.

Results: Complete data were obtained for 94 Malay and 78 Indian patients (median age, 54 years and 51 years, respectively). At the attribute level, all 16 hypotheses were fulfilled with several reaching statistical significance (Malay: 4; Tamil: 5). At the overall level, 42 of 44 hypotheses related to the EQ-5D/ EQ-VAS were fulfilled (Malay: 22; Tamil: 20), with 21 reaching statistical significance (Malay: 9; Tamil: 12).

Conclusion: In this study among primary care patients, the Singapore Malay and Tamil EQ-5D demonstrated satisfactory known-groups and convergent validity.

Key words: Primary Health Care, Psychometrics, Quality of Life
Ovarian Carcinoma Presenting With Isolated Contralateral Inguinal Lymph Node Metastasis: A Case Report
Authors: Ang Daphne , Ng Keng-Yeen , Tan Han-Koon , Chung Alexander YF , Yew Boon-Siang , Lee Victor KM
Published: February 2023

Introduction: Ovarian carcinoma usually presents at an advanced stage with diffuse intraabdominal manifestations. We report a patient who presented with a right groin swelling.

Clinical Picture: The only clinical abnormality was an enlarged right inguinal lymph node (3 x 2 cm), for which excision biopsy revealed metastatic adenocarcinoma. A computed tomography (CT) scan showed an enlarged left ovarian lesion (9.0 x 6.4 cm). Treatment and

Outcome: Laparotomy with total hysterectomy, bilateral salpingo-oophrectomy and partial omentectomy were performed. Histology confirmed left ovarian adenocarcinoma, consistent with the earlier histology of the right inguinal lymph node. There were no other sites of involvement. Postoperatively, the patient received adjuvant chemotherapy for treatment of FIGO Stage IIIc ovarian carcinoma and is clinically disease free 13 months after surgery.

Conclusions: Ovarian cancer presenting with inguinal lymph node metastases is uncommon. Ovarian cancer which manifests solely as a contralateral inguinal lymph node metastasis has not been previously reported. This case illustrates a rare presentation of ovarian carcinoma, and underscores the need to consider ovarian carcinoma in the differential diagnosis of women with inguinal lymphadenopathy.

Key words: Inguinal lymph node metastasis, Ovarian adenocarcinoma
Cefepime-induced Encephalopathy with Triphasic Waves in Three Asian Patients
Authors: Silva Deidre Anne De , Pan Andrew BS , Lim Shih-Hui
Published: February 2023

Cefasporins such as cefepime are beta-lactam antibiotics with a broad antimicrobial spectrum. They are commonly used as first-line agents in the treatment of many infections.1 Reversible encephalopathy is a known neurotoxic complication of cefalosporins.2 Previous case reports have documented triphasic waves on electroencephalography (EEG) in cephalosporin-induced encephalopathy.1-4 Cefalosporin-induced encephalopathy with triphasic waves has not been previously reported among Asians. We report 3 Asian patients with toxic encephalopathy and documented triphasic waves on EEG while on treatment with cefepime.
Academy of Medicine, Singapore – The First Twenty-Five Years (1957-1982)
Authors: Chew Chin-Hin , Lim Pin
Published: February 2023

The Academy of Medicine, Singapore celebrates its Golden Jubilee in July 2007. This paper reviews some significant milestones of the Academy from 1957 to 1982. Postgraduate medical education with specialist training and assessment was more formalised only during the challenging years when Singapore became more autonomous and politically independent. This also coincided with the establishment of the Academy of Medicine and the University's School of Postgraduate Medical Studies. The close relationship between the two bodies and the Ministry of Health continues to this day. The historical links with the British and other international Colleges and Academies are also highlighted.
The History and Development of the Chapter of Obstetricians and Gynaecologists / College of Obstetricians and Gynaecologists
Authors: Ho Tew-Hong
Published: February 2023

The Chapter of Obstetricians and Gynaecologists (O&G), started by a pioneering group of nine O&G specialists in 1969, had as its main objectives of encouraging postgraduate training, education and research. In the years that followed, continued medical education and professional development played an important aspects of the Chapter's activities, in close collaboration with our sister societies and organisations. Close regional and international links were also made and renowned Visiting Fellows/Academicians from overseas were invited by the Chapter to speak and participate in academic activities. The Academy of Medicine took a momentous step in March 2004 to transform Chapters into autonomous Colleges. The College of Obstetricians and Gynaecologists, Singapore was officially inaugurated on 14 August 2004. In the tradition of its predecessor, the College continues to involve itself in training, continued medical education and examination activities. This also included producing consensus guidelines and distance learning programmes for the purpose of achieving best practices. An important milestone was the signing of the MOU on 3 September 2005 for the conjoint MRCOG/MMed examination between the RCOG and the College of O&G, Singapore. The first conjoint MRCOG/MMed examination was held on 8 May 2006. The College is well poised to address the challenges ahead including keeping the high standards of practice and ensuring that every practitioner maintain competence in his practice.

Key words: College of Obstetricians and Gynaecologists, Chapter of Obstetricians and Gynaecologists, Conjoint MRCOG/MMed examination
Avoiding Dialysis in Tumour Lysis Syndrome: Is Urate Oxidase Effective? – A Case Report and Review of Literature
Authors: Teo Wan-Yee , Loh Tsee-Foong , Tan Ah-Moy
Published: February 2023

Introduction: Hyperuricaemia in tumour lysis syndrome (TLS) can cause acute renal failure (ARF), necessitating dialysis. Recombinant urate oxidase (rasburicase) converts uric acid to soluble allantoin, which is excreted easily.

Case Report: An 8-year-old boy with stage 3 Burkitt’s lymphoma, TLS was successfully treated with hyper-hydration, diuretics and rasburicase, without dialysis. This is the first paediatric case in Kandang Kerbau Women’s & Children’s Hospital (KKH) in which rasburicase was used. We review the literature on the effectiveness of urate oxidase in avoiding dialysis in TLS.

Treatment and Outcome: Our patient developed rapidly rising serum uric acid (SUA) and progressive renal impairment. Hyper-hydration and rasburicase (0.2mg/kg) were administered. SUA rapidly decreased from 1308 to 437 mmol/L within 12 hours. Urate oxidase has shown better results than allopurinol. There was a need for dialysis in 0.4% to 1.7% of patients with haematological malignancies given rasburicase, compared to 20% in patients given allopurinol.

Conclusions: Rasburicase can reverse renal insufficiency. Though expensive, it may be cost-effective by lowering incidence of dialysis, shortening the duration of intensive care and hospitalisation, allowing early chemotherapy.

Key words: Acute renal failure, Hyperuricemia, Recombinant urate oxidase, Renal insufficiency
Neurogenic Pulmonary Oedema Misdiagnosed as Acute Myocardial Infarction in a Comatose Patient
Authors: Seow Vei-Ken , Ko Shih-Yu , Huang Meng-Kai , Chong Chee-Fah
Published: February 2023

Introduction: We report a case of neurogenic pulmonary oedema (NPO) following massive left cerebral infarct, which was initially misdiagnosed as acute myocardial infarction (AMI).

Clinical Picture: This 52-year-old man presented with acute loss of consciousness with normal brain computed tomography (CT). He was treated as non-ST-elevation AMI complicated with pulmonary oedema based on findings of chest radiograph (bilateral pulmonary oedema), electrocardiogram (marked ST-T changes in leads V3 to V6), and cardiac enzymes [elevated creatinine kinase (CK) and CK-MB]. However, coronary angiogram and serial cardiac enzymes were inconclusive. Anisocoria developed after admission and a repeat brain CT was evident for large left cerebral infarct.

Treatment: Decompressive craniectomy was carried out.

Outcome: Mortality.

Conclusions: The diagnosis of NPO can be challenging when it occurs without abnormal findings on preliminary brain CT. It can be mistaken for cardiogenic pulmonary oedema secondary to AMI.

Key words: Cerebral infarction, Neurogenic pulmonary oedema, Stroke
A Review of Geriatric Education in Singapore
Authors: Koh Gerald CH
Published: February 2023

The United Nations has identified the training and education of healthcare professionals and care providers involved in the care of older persons as a global priority. Singapore is no exception as it faces a rapidly ageing population. Older people have many medical needs of varying dimensions and their care requires a multidisciplinary healthcare team. The current status of geriatric education of health professionals involved in elderly care in Singapore is discussed in this paper. Important issues raised include the disparity between professions in the stages of development of geriatric education, questions on the adequacy of numbers and training of healthcare professionals providing geriatric care, as well as the need for geriatric education of caregivers.

Key words: Ageing population, Caregiver, Elderly, Healthcare professional
Online Quality of Services of Ship Procurement License at Kesyhbandaran Utama Tanjung Perak Surabaya Office
Authors:   Master of Public Administration, Faculty of Social Science and Political Science, Hang Tuah University Surabaya Indonesia, Muslim Muslim , Umiyati Sri ,   Master of Public Administration, Faculty of Social Science and Political Science, Hang Tuah University Surabaya Indonesia, Siswanto Djoko ,   Master of Public Administration, Faculty of Social Science and Political Science, Hang Tuah University Surabaya Indonesia
Published: February 2023

One of the efforts to create optimal services quickly and cheaply is by providing information technology for integrated exchange of data and information. Tanjung Perak Surabaya Main Harbormaster Office implements an online service system in accordance with the Regulation of the Minister of Transportation of the Republic of Indonesia PM Number 154 of 2015 concerning Online Syahbandar Approval Letter Services, including the service of Ship Motion Approval Letters at the Port. The government through the Ministry of Transportation developed Inaportnet, which is an internet-based electronic single service system. The Inportnet concept is applied as a ship service system in terms of ports in the activities of arrival and departure of ships as well as plans for loading and unloading activities that can be carried out effectively and efficiently. The purpose of this research is to describe and analyze the Quality of Service for Ship Motion Permit Online at the Tanjung Perak Surabaya Main Harbormaster Office using the theory of electronic service quality by Ribbink et. al (2004). This research method is descriptive research with a qualitative approach, data collection is done by interview, observation, and documentation techniques. The results obtained are then collected, reduced, presented, and conclusions are drawn. The results of this study indicate that the Quality of Service for Ship Motion Permits Online at the Tanjung Perak Surabaya Main Harbormaster Office shows that service quality is not optimal. It is said that it is not optimal because there are dimensions that do not meet the needs of service users, namely: there is no complaints and suggestions menu in the Inaportnet application, there is no data correction menu if an error occurs in the data input process so that service users have to process data input repeatedly, of course impede the work of shipping agents, especially in the process of applying for ship operating permits online.
VRIO Analysis in the Commercialization of the Traditional Music Industry
Authors:   School of Business Management, Institut Teknologi Bandung, Erlangga Hartana ,   School of Business Management, Institut Teknologi Bandung
Published: February 2023

Art is one of the elements of human culture in general which is an expression of the creativity of the culture itself. Culture-based creativity is a reflection or uniqueness of a nation’s identity. However, in the current era of globalization, traditional arts are increasingly being abandoned by the public. Based on the data released by jabarprov.go.id about West Java arts’ status state that there are several traditional arts that are almost extinct and there will be an increasing number of traditional arts that follow extinction. One of the reasons is that the current generation is more interested in popular music than traditional music or in other words they are not sufficiently concerned about their own culture. This is also because many think that traditional art is outdated. Not only experiencing extinction, several Indonesian traditional arts have also been claimed by other countries. Quoting from kompas.com (2010) in his article entitled “Angklung Will Become a World Cultural Heritage” which also discussed where angklung as a traditional art from Indonesia was claimed by another country which infuriated the Indonesian people, and after the debate between Indonesia and Malaysia. Angklung then was registered as an Intangible Cultural Heritage (ICH) of Indonesia at UNESCO in November 2010. In order to actively participate in preserving and maintaining the existence of angklung in society, RagamLaras came up with an innovation for angklung, where the RagamLaras angklung has 15 scales that can play both pentatonic and diatonic notes in one angklung ensemble. It is hoped that it can provide a new presentation for the performing arts of angklung and open space for creativity for traditional artists, as well as spreading the public awareness, especially the younger generation, to get to know and preserve the nation’s culture better.
Tax Management System for Local Government Unit with SMS Notification
Authors:   College of Information and Computing Studies, Northern Iloilo State University, Estancia, Iloilo, Philippines, B. Bañes Arnold
Published: February 2023

This study aimed to design and develop a Tax Management System for Local Government Unit with SMS Notification and evaluate the degree of acceptability and performance efficiency in the perception of the respondents. It is a computer-based information system aimed at providing information of the tax payers and their payment history in fast and easy manner. Developmental and descriptive research design was employed in this study. A system prototype was developed to implement the core functionalities as required by the target users to meet design specification. This study was conducted at the Treasurer Office in the Municipality of Estancia, Iloilo with a total of 50 respondents. When respondents were asked as to the degree of acceptability of the developed system in terms of security, it yielded a response of strongly agree. In terms of confidentiality, the developed system was described as strongly agree. The result showed that the performance efficiency of the developed system in terms of time behavior was also described as strongly agree. In terms of responsiveness, the developed system was also described as strongly agree. From the results stated above, this simply showed that the respondents were very much contented with the security, confidentiality, and efficiency of the developed system.