bluuebunny/crossref_metadata_2025 huggingface dataset:
Herth Hope Index: A Psychometric Evaluation Study within a Sample of Greek Patients with Cancer
Authors: Nikoloudi Maria , Tsilika Eleni , Parpa Efi , Kostopoulou Sotiria , Tentolouris Anastasios , Psarros Constantin , Alexandra Mantoudi , Mystakidou Kyriaki
Published: September 2021

Objectives:

This study aims to develop the Greek version of the Herth Hope Index (HHI) and assess its psychometric properties to a palliative care patient sample, using a cross-sectional design.

Materials and Methods:

The HHI was translated into Greek (HHI-Gr) using the ‘forward-backward’ procedure. It was administered to 130 eligible cancer patients, while for the stability of patients’ responses, 40 of these patients completed the HHI-Gr 3 days later. Along with the HHI-Gr, patients also completed the Hospital Anxiety and Depression Scale (HADS) and the Beck Hopelessness Scale (BHS). The HHI-Gr internal consistency reliability (Cronbach’s a), stability (intraclass correlation coefficient [ICC]), factor structure (factor analysis) and convergent validity (correlation with the HADS and the BHS questionnaires) were examined using the Eastern Cooperative Oncology Group (ECOG) performance status.

Results:

The HHI-Gr yielded a one-factor model and a Cronbach alpha (0.860) with excellent internal consistency reliability and stability ICC (>0.90). Satisfactory convergent validity was supported by the correlation analysis between the HHI-Gr and BHS (r = 0.718, P < 0.001). Overall test-retest reliability was satisfactory with a range between 0.77 and 0.96 (P < 0.001).

Conclusion:

These results demonstrate that the HHI-Gr is an instrument with satisfactory psychometric properties and is a valid research tool for the measurement of the levels of hope among Greek oncology patients.
Evaluation of rhizosphere Streptomyces for zinc solubilizing and plant growth promoting properties
Authors: Balakrishnan K. , Radhakrishnan Manikkam , Gopikrishnan Venugopal , Thirumalairaj J. , Balagurunathan Ramasamy
Published: September 2021

Actinobacteria were isolated from rhizosphere soil and its plant growth-promoting ability was tested. Actinobacteria were screened for promoting plant growth by phosphate and zinc solubilization, gibberellin, siderophore, HCN and indole-3-acetic acid production. The abiotic stresses of all the isolates were tested for parameters such as pH, temperature and NaCl. Upon screening, a potent actinobacteria named Streptomyces sp. ZS-18 was isolated and identified based on the colony characteristics. The potent strain solubilized both the zinc oxide (26 ± 0.75mm) and zinc carbonate (22 ± 0.88mm). The utilization of gibberellic acid (80μg/ml) by the potential strain ZS-18 showed maximum production measured by optical density value of 0.179. The growth of the green gram plant was determined by shoot, root, total length, number of leaves and chlorophyll estimation of the leaves. Streptomyces sp. ZS-18 showed good growth on ISP 1, ISP 2, ISP 3, ISP 5 and ISP 7 medium and moderate growth was observed in ISP 4 and ISP 6 medium. In addition, Actinobacteria were tested for antagonistic activity against plant pathogens. The isolate ZS-18 in the pot trial experiment showed increased growth in comparison with control and cow dung manure.
Zwischen Physiokratie und Landschaftsverschönerung: Die Kulturlandschaft Reinhardsgrimmas
Authors: Leukefeld Tom
Published: September 2021

In seinem Beitrag geht der Autor auf die Kulturlandschaft Reinhardtsgrimmas ein. Im Fokus stehen die Landschaftsentwicklungen und Landschaftsverschönerungen, die seit Ende des 18. Jahrhunderts eine besondere Bedeutung für das Schloss Reinhardtsgrimma inne haben.
Die Entwicklung der Gärten des Rittergutes in Reinhardtsgrimma
Authors: Gottschalk Anja
Published: September 2021

Die Autorin berichtet über die Geschichte des Schlossgartens Reinhardtgrimmas. Beginnend im 17. Jahrhundert wird die Historie und Weiterentwicklung der Gutsgärten, bis ins 20. Jahrhundert erklärt.
Vorwort
Authors: Kitt Thomas
Published: September 2021

Kurzes Vorwort von Thomas Kitt, Seminarbereichsleiter für Umwelt im Bildungszentrum Reinhardtsgrimma.
Microbial Cellulases: A Review on Strain Development, Purification, Characterization and their Industrial Applications
Authors:   National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan, H Sher , N Zeb ,   National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan, S Zeb ,   Department of Microbiology, Abdul Wali Khan University Mardan, KP, Pakistan, A Ali ,   Department of Microbiology, Abdul Wali Khan University Mardan, KP, Pakistan, B Aleem ,   National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan, F Iftikhar ,   National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan, SU Rahman ,   National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan, MH Rashid ,   National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan
Published: September 2021

In this advance era, the enzymes are considered as a core kernel of white biotechnology and their demand is increasing day by day. According to report published in Research and Markets (ID: 5009185), the estimated global market for industrial enzymes were USD 10.0 billion in 2019, which is continuously increasing as it is expected to reach about USD 14.7 billion by 2022. Among all enzymes, cellulases are the major group of enzymes act synergistically in breakdown of cellulose, that facilitates its conversion to various value-added products and also offer several other important applications at industrial scale. The hyper production of cellulases are required to overcome their demand of global market. Cellulases production can be enhanced by strain improvement as well as using advance fermentation technology. In this review a detail studies of strategies to enhance production of cellulases and improve their physiochemical properties for industrial application have been described.
Mucormycosis: An Epidemic Associated with Pandemic- A Systematic Review
Authors: Mir Tabish Syeed  , Ishita Mamgain  , Diksha Sharma  , Ishan Trisal
Published: September 2021

Different infections have been presenting danger to mankind every once in a while and in 2019 a serious respiratory illness (COVID-19) reported in Wuhan, Hubei province of China, became a threat to general wellbeing not only in China but all the nations throughout the world. COVID-19 disease which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is found to be associated with a wide range of opportunistic fungal and bacterial infections. Candidial and aspergillus infections leading to mucormycosis and orbital compartment syndrome have been reported to be the main co-infections in COVID-19 patients, which must be recognized and treated promptly to avoid any morbidity and mortality. Low oxygen environment, acidic medium, high glucose, decreased phagocytic activity and increased ferritin levels in addition to prolonged hospitalization with or without mechanical ventilators are considered as the main risk factors. Thus, the main aim of the article is to briefly survey and discuss about the types, causes, methods to prevent and treatment modalities of main co-morbidity of COVID 19 i.e. mucormycosis.
Operationalizing Command Centre for COVID-19 Care Services in a Tertiary Care Teaching Hospital
Authors: Sanika Ratnakar Kulkarni  , Henna Dhar
Published: September 2021

COVID-19 was declared a public health emergency of international concern by WHO in March 2020. Hospitals were overburdened, health workers were drained and resources were depleting due to which people were desperately looking for hospital beds, medical oxygen and other necessities. For this purpose, a command centre was set up by the hospital administration department. The command centre targets for the enhancement of patient outcomes by coordination of care and centralized quality control. The main objectives of the command centre include internal communication between the departments concerned with COVID-19 care, appropriate resource allocation in the hospital for COVID-19 care and data compilation and dissemination of the real time data from COVID-19 war room to government organizations. The COVID-19 war room functions daily in a dedicated manner which helps in strategic planning and managing all the functions efficiently. The command centre though works dedicatedly, certain challenges are faced while carrying out the functions.
The agreed experts’ position of the Eurasian Association of Therapists on tactics of management of patients with comorbid pathology infected with SARS-Cov-2
Authors: Arutiunov G. P. , Tarlovskaia E. I. , Koziolova N. A. , Boldina M. V. , Batiushin M. M. , Ametov A. S. , Arutiunov A. G. , Belevskii A. S. , Galstian G. R. , Grigor’eva N. I. , Dzhunusbekova G. A. , Esaian A. M. , Mal’chikova S. V. , Mit’kovskaia N. P. , Mkrtumian A. M. , Orlova I. A. , Petrova M. M. , Rebrov A. P. , Ruzanov D. I. , Salukhov V. V. , Sisakian A. S. , Skibitskii V. V. , Sugraliev A. B. , Fomin I. V. , Khalimov I. S. , Chesnikova A. I. , Shaposhnik I. I. , Shestakova M. V.
Published: September 2021

The agreement of experts of the Eurasian Association of Therapists (EAT) discusses pathogenesis and treatment of COVID-19. Modern data on the characteristics of cardiovascular, kidney, respiratory damage in SARS-infected CoV-2 are presented. The tactics of managing patients initially having cardiovascular diseases, diabetes mellitus, chronic obstructive pulmonary disease, bronchial asthma, chronic kidney disease are discussed in detail. The article presents data on drug interaction of drugs.
Current view on Blastocystis species: clinical forms, diagnosis and treatment
Authors: Maleev V. V. , Tokmalaev A. K. , Kozhevnikova G. M. , Tsvetkova N. A. , Polovinkina N. A. , Golub V. P. , Maksimova M. S. , Barysheva I. V. , Konnov V. V. , Kharlamova T. V.
Published: September 2021

The symptomatic form of Blastocystis spp. infection not only with mild diarrhea or dysentery-like syndrome, but also with the development of severe ulcerative necrotic lesions of the intestine. Meanwhile, the pathogenicity of these microorganisms should not be exaggerated, due to majority asymptomatic cases or infection transmission with minor impaired bowel function.
The Character of Abdulkarim Qasim is Between National and Communist Discourse
Authors: Mustafa Suzan Karim
Published: September 2021

In the revolutions of history, an individual or leader is always given a higher role than all perpetrators of events, leaders have always been recognized as heroes in history, and a leader has faced all the factors of success and failure. In all societies, one or more people have always appeared and dominated the entire political and economic spheres of the country, a factor in the self-perception of history, or the hegemony of history, while the achievements of history belong only to one or the first leader, the total number of participants in the process of changing roles and his Impact on the direction of events.
Abdul Karim Qasim is an example of a leader in Iraq who went from revolution to dictatorship, while people looked at him with hope and described him as a leader who changed the course of history, the reason for his failure was the conflict between political parties and the international community.
This study is the gateway to getting to know Abdul Karim Qasim's personality from the point of view of his opponents. In this two-part study, we discussed the beginnings of Abdul-Karim Qasim’s relations with political parties, and the views of the nationalist and communist parties towards Abdul-Karim Qasim, relying on several sources of different ideologies.
Milieu therapy as a method for improving the quality of life of the old people
Authors: Oprya Yevgen , Pustovoyt Mykhailo
Published: September 2021

Relevance. Nowadays, both in developing countries and in industrialized countries, there is a process of increasing life expectancy, which together with the problem of low birth rates leads to the phenomenon of “aging population”. Providing care to the elderly is not only a purely medical problem, but the social aspect is equally important. An important component of the lifestyle of an elderly person is recreation - the processes of restoring vitality, relieving mental stress and recovery, carried out in various forms of recreation, nutrition, active or passive leisure. Modern society and the health care system face three most important tasks: continuing an active life with minimal losses from the disorders inherent in old age, combating high morbidity in old age and ensuring a dignified end to the lives of aging people. Although the provision of medical and social assistance to the elderly is organized and provided as needed, ensuring the accessibility and sufficient presence in their lives of the social aspect and its communicative component is not supported in our country at the state level and is not regulated by law. Purpose. The purpose of the work is to improve the quality of life of the elderly through the organization of the social component of life by arranging their leisure. Results. To achieve this goal, it was proposed to use the principles and methods of milieu therapy, which means “treatment by the environment”. Most often, milieu therapy refers to a form of psychotherapy that involves the use of therapeutic communities. Considering the goal, milieu herapy fully covers and meets the goals of rehabilitation of the elderly, and as a social technology allows to create an active living environment that encourages older people to “independent actions”, self-sufficiency, withdrawal from dependent moods and hyperprotection. Milieu therapy allows to activate the living environment of such people in accordance with their needs, interests, psychophysical condition, rehabilitation potential; and to optimize the work of staff in the direction of improving the efficiency of activities that will have a direct impact on quality of life. On the example of other countries, examples of the use of the principles of milieu therapy in the organization of daytime activities in the elderly are provided. Conclusions. Providing leisure for the elderly will be able to improve their quality of life, reduce the prevalence of somatic diseases and the risk of developing psychosomatic conditions in them, and thus reduce the burden on health care facilities. And the use of the principles of milieu therapy to solve problems will allow to organize it as effectively as possible.
The Legal Implication of Political Defection on Nigeria’s Democracy
Authors: Nuhu Khalid Idris
Published: September 2021

The prevalence of cross-carpeting in Nigerian politics continues to threaten the consolidation of democracy in the country. It is strengthened by the proliferation of political parties devoid of entrenched ideology or political philosophy besides attaining political and economic powers. The unusually delayed justice in defection related matters sometimes occasioned by the pile of cases before the scanty judicial umpire in the country is another block of stumbling over. The technical approach of these umpires to cases of defection or constitutional matters may not be far from being a cloak on the wheel of justice. While the elected executives at the detriment of their electorates enjoyed the freedom of assembly and association in changing their political parties after the election, the exercise of the same right by the elected members of legislative houses are subjected to certain occurrences in justification or else vacate their seats on the pronouncement of their respective leaders in the house. This historical political menace persistently thrives in the country's fledgling democracy without adequate legal instruments for effective redress. Through the conceptual approach, the study reveals that the elected executives persistently swindle the mandate of their voters with impunity while the principal officers of the parliaments freely decide who remains or exits the house on the ground of defection. It is clear that the Nigerian Anti Defection Law is inadequate in the changing political landscape of the country. This paper recommends a law reform to affect some enactments, particularly in the Constitution whereby machinery for the vacation of a seat in the parliament after defection can be beyond the powers of the principal officers, which is necessary for the attainment of socio-political orders in the country.
Pedagogia da resistência
Authors: Freitas Marinaide , Menezes Anderson , Cavalcante Valéria Campos
Published: September 2021

No presente artigo, evidenciamos as contribuições das leituras de Freire (1975, 1979, 1992, 2005) e Honneth (2009, 2018) que fizeram parte da nossa trajetória profissional. Ressalta-se que nos percursos que vivemos em momentos distintos, na condição de professores/as, pesquisadores/as da Educação, tivemos a oportunidade de vivenciar práticas pedagógicas inovadoras, grande parte, com base no legado bibliográfico de Paulo Freire, que nos possibilitou/possibilita valorizar a relevância da ação político-pedagógica nas escolas. Trazemos o recorte de uma pesquisa realizada em quatro escolas públicas de Alagoas, investigação inserida no Observatório Alagoano de Leitura na EJA, que nos conduziram a constatar que as escolas se configuram como espaçotempo de exercício de autonomia, de estudantes e professores, apropriando-se da realidade. Inspirados ainda em Freire (1979) reafirmamos o compromisso com a Educação como prática da liberdade. Nesse contexto, a palavra é compreendida como “força de transformação do mundo”. Assim, podemos pensar com Freire (2005) e Honneth (2009; 2018) nas formas de engajamento e luta que evocam processos de humanização e libertação frente aos contextos de profunda coisificação e consequente esquecimento do reconhecimento subjetivo e social.
Interculturalidade e inclusão
Authors: Alves Novais Souza Adriana , Da Silva Veleida Anahí , Santos Souza Rita de Cácia
Published: September 2021

As discussões da decolonialidade têm por foco o oprimido, o aculturado, todo aquele que, apesar dos discursos em prol da diversidade, ainda sofre subjugo da cultura do colonizador, sendo desconsiderado em seus saberes, sua língua e cultura. Trata-se de um estudo bibliográfico, apoiado em Gil (2008), cujo objetivo é discutir a inclusão escolar de pessoas surdas no Brasil e as condições em que se deram tais políticas, a partir da análise de viés decolonial, especificamente segundo os conceitos de interculturalidade funcional e crítica, na perspectiva de Catharine Walsh.  Nesse diálogo com as leituras decoloniais, lançamos um olhar crítico e mais aprofundado às políticas de inclusão escolar e de como o modelo educacional proposto, bastante superficial, não atende de forma efetiva às necessidades educacionais dos alunos surdos e segue, ao invés da inclusão proposta, excluindo-os e invisibilizando-os.
Atitudes socioambientais na educação infantil
Authors: Oliveira Gilvaneide Ferreira  de , Silva Renata Carvalho da
Published: September 2021

Este trabalho traz resultados de uma investigação sobre as estratégias didático-pedagógicas realizadas em um CMEI da rede municipal de Recife, tendo como objetivo compreender as dificuldades e possibilidades de trabalhar a Educação Ambiental crítica numa perspectiva atitudinal, rompendo com abordagens naturalísticas. Considera-se a necessidade de práticas educativas socioambientais inovadoras, inseridas desde a infância, fundamentadas em questões socioambientais transformadoras e emancipatórias, abordadas numa dimensão transdisciplinar, voltada para a formação cidadã de atitudes sustentáveis. Nesse sentido, indaga-se: quais as dificuldades e possibilidades de se trabalhar a Educação Ambiental na perspectiva atitudinal no contexto da Educação Infantil? Trata-se de um Estudo de Caso, de cunho qualitativo, investigado através de observações, entrevistas semiestruturadas e análise documental. Utiliza-se a triangulação dos dados para a análise dos resultados, estabelecendo um diálogo crítico com a base teórica referenciada no início deste trabalho. Os resultados apontaram para um repensar das práticas didático-pedagógicas de Educação Ambiental na Educação Infantil, no sentido de refletir criticamente, buscando atingir uma efetiva ruptura com as bases conservadoras que orientam as práticas da educação socioambiental no referido contexto.
Results on C2-paracompactness
Authors: Alzumi Hala , Kalantan Lutfi , Saeed Maha Mohammed
Published: September 2021

A C-paracompact is a topological space X associated with a paracompact space Y and a bijective function f : X âˆ’â†’ Y satisfying that f A: A âˆ’â†’ f(A) is a homeomorphism for each compact subspace A âŠ† X. Furthermore, X is called C2-paracompact if Y is T2 paracompact. In this article, we discuss the above concepts and answer the problem of Arhangelâ€™ski Ì†i. Moreover, we prove that the sigma product Î£(0) can not be condensed onto a T2 paracompact space.
COVID-19’UN BİST SEKTÖRLERİNE ETKİSİ
Authors: ŞENOL Zekai , OTÇEKEN Gülşah
Published: September 2021

2020 yılı başlangıcında Çin’de ortaya çıkıp kısa süre içinde dünya genelinde salgın hastalık haline gelen COVID-19 ekonomileri, borsaları ve dünya ticaretini derinden etkilemiştir. COVID-19’a bağlı olarak virüsten korunma, virüsün yayılmasını önlemeye yönelik ekonomik ve sosyal yaşamda alınan tedbirlerin sektörlere yönelik etkileri farklı olmuştur. Sağlık, teknoloji ve perakende dağıtım gibi sektörler COVID-19 sürecinde ön plana çıkarken ulaşım ve turizm gibi sektörler salgından olumsuz etkilenmişlerdir. Bu çalışmada COVID-19’un Borsa İstanbul (BİST) sektör endekslerine etkisi araştırılmıştır. Ocak 2020 – Nisan 2021 dönemine ait haftalık verilerle Johansen eşbütünleşme testi ve Toda Yamamoto nedensellik testleri yapılmıştır. Çalışmada, COVID-19’un sektörleri farklı şekilde etkilediği, COVID-19 ile mali ve sanayi sektörleri arasında ilişki olduğu, COVID-19’dan mali ve sanayi sektörlerine doğru bir nedenselliğin bulunduğu tespit edilmiştir. Ortaya çıkan sonuçlar, portföy yönetimi, risk yönetimi ve ekonomi yönetimi bakımından kullanılabilirlik taşımaktadır.
OPTIMIZATION OF ADSORPTION OF Pb (II) AND Cr (VI) FROM AQUEOUS SOLUTION USING MODIFIED FELDSPAR COMPOSITE: ISOTHERM AND KINETIC STUDIES
Authors: Sanusi Kabir A. , Yahaya Yakubu , Ambrusa Murtala M. , Yahaya Yakubu , Hammed Abdulazeez M.
Published: September 2021

In this study modified feldspar composite (MFC) adsorbent based on feldspar and Theobroma cacao podas (TCP) was prepared, characterized and utilized for adsorption of Pb (II) and Cr (VI) in aqueous solution. The results showed that the cation exchange capacity of the modified feldspar composite (30.66 ± 0.21 meq/100 g) was 5 times higher than that of raw feldspar (6.42 ± 0.45 meq/100g). More so, the novel biohybrid material, MFC has a surface area of 53.60 ± 0.3 m2/g and particle size of 105.4 ± 0.18. X-ray diffraction peaks revealed that after the modification process, there is only slight shift in the position of some diffraction peaks of feldspar and the composite material suggestive of the retention of the crystalline properties of the feldspar in the novel composite (MFC). Infrared spectroscopy (FTIR) spectra showed that some functional groups present in the two starting materials were also available on the surface of the composite (MFC) indicating that the intercalation of TCP biomass into feldspar surface was successful. Response surface methodology (RSM) via a five-levels central composite design (CCD) was applied for optimization of  metal adsorption onto the adsorbent in 32 experiment runs considering the effect of pH, adsorbent dose, adsorbate concentration and contact time. Optimization results showed that the predicted and experimental values of Pb (14.021, 14.148 mg/g) and Cr (3.428, 3.504 mg/g) were close at the optimum condition of (pH 2, 5, 6; 0.5 g; 100 mg/L; 60-120 min and 3000K). Results of ANOVA analysis revealed the adequacy of the model with the good correlation between R2 values (0.9916-0.9998) and adjusted R2 (0.9919-0.9986) and F value of (≥ 147). Results showed that Pb (II) ions adsorption onto the adsorbents was well fitted to the Langmuir isotherm model while the Cr (VI) ions uptake onto FS and MFC adsorbents followed Freundlich isotherm model. The results of the kinetic studies showed that rate of Pb (II) removal followed pseudo second order model while the rate of adsorption of Cr (VI) onto the FS and MFC adsorbents best fitted pseudo first order model. Owing to its improved cation exchange capacity and eco-friendliness, the modified feldspar composite have a good potential application in wastewater treatment besides other industrial explorations.
decadencia de las lenguas autóctonas de Guinea Ecuatorial: una manifestación de la pérdida de identidad cultural
Authors: Bituga-Nchama Pedro , Nvé-Ndumu Cruz
Published: September 2021

El presente estudio se centra en el análisis de la situación sociolingüística de Guinea Ecuatorial. En este sentido, se parte del hecho de que la falta de aprendizaje de las lenguas autóctonas del país ha derivado en una pérdida de identidad cultural, la cual se ha visto agravada por otros factores como la globalización. La poca importancia que se presta a las lenguas autóctonas, hace que todas ellas estén sufriendo cambios que provocarían su decadencia y posterior desaparición. Se debe invertir en políticas lingüísticas que puedan contrarrestar este efecto porque cuando desaparece una lengua lo hace también una parte de la misma cultura. Es importante remarcar que esta investigación no se ancla en el relativismo lingüístico por cuanto reconoce que potenciar las lenguas autóctonas no es una manera de vetar las lenguas oficiales del país. En la actualidad existe una pérdida de identidad cultural motivada porque no se enseña a los niños las lenguas autóctonas, pretenden que sean políglotas o bilingües sin una base lingüística propia: nos referimos a sus lenguas autóctonas que les identifican como parte de un grupo o comunidad. A lo largo de este trabajo, se pone de manifiesto que no puede haber políticas culturales sin políticas lingüísticas, porque las personas deberían conocer las lenguas autóctonas de su cultura. De hecho, los principales resultados de esta investigación evidencian la necesidad proteger las lenguas autóctonas, es incoherente potenciar el español en detrimento de las lenguas autóctonas que representan la identidad de cada grupo étnico.
“This is not about gambling, it’s about our lives”
Authors: Manitowabi Darrel , Wahsquonaikezhik Sheila
Published: September 2021

In this interview, Darrel Manitowabi speaks to Sheila Wahsquonaikezhik, Director of Indige-Spheres to Empowerment, a non-profit organization addressing Indigenous health and wellness. This interview explores Sheila Wahsquonaikezhik’s Indigenous gambling experience including work in an Indigenous casino in Ontario, gambling harm reduction outreach in northwestern Ontario First Nations, and gambling research collaborations. An outcome of this interview is a revelation that the practice of Indigenous gambling is connected to the wider context of colonialism and Indigenous gambling research requires greater inclusion of Indigenous peoples.
WAI 1909 – The Waitangi Tribunal Gambling Claim
Authors: Herd Ruth Ann
Published: September 2021

In 2008, I lodged a claim with the Waitangi Tribunal in regard to problem gambling and its negative impacts on Māori people. The Tribunal is tasked with hearing grievances related to Te Tiriti o Waitangi (The Treaty of Waitangi) signed in 1840 between Māori and the British Crown.  It is a historical claim focused on the lack of adequate protection of taiohi Māori (young people of Māori descent) and the intergenerational harm caused by problem gambling among their whānau, hapū, iwi (extended families and relatives) and urban Māori communities. However, this begs the question how can a Treaty claim improve the health outcomes of a generation of taiohi Māori who have been exposed to commercial gambling and its aggressive and targeted expansion and marketing?  This paper frames the WAI-1909 claim as a Kaupapa Māori (Māori research approach) derived from the research of three wahine toa (warrior women) supporting the claim; and refers to epistemological standpoints of Māori women working in the gambling research space. I demonstrate how the gambling claim challenges the New Zealand government to honour the promises in the articles of Te Tiriti o Waitangi and to protect the rights of its citizens, especially taiohi Māori. The WAI-1909 gambling claim concludes that whilst the New Zealand Gambling Act (2003) includes a public health approach to problem gambling, it has not adequately addressed the rights of tangata whenua (Māori, the first people of Aotearoa/New Zealand) under Te Tiriti o Waitangi.
Actual possibilities of pathogenetic treatment of patients with with purine dismetabolism
Authors:   Sechenov University, Rudenko V.I. ,   Moscow, Russia, Demidko Yu.L. ,   Sechenov University; Moscow, Russia, Krayev I.G. ,   Medical hospital № 152 FMBA of Russia; Moscow, Russia
Published: September 2021

Introduction. Purine dysmetabolism is occured by increased production of uric acid, which leads to hyperuricemia and hyperuricuria. The most common forms of purine metabolism disorders are the uratenephropathy, gout, and asymptomatic hyperuricemia. Purpose. To evaluate the data published from 1992 to 2021 on the prevalence, forms of purine metabolism disorders, diagnostics and methods of their treatment. Two hundred and seventy original publications were identified, of which 37 were selected and analyzed. Materials and methods. The search results in the scientific database PubMed, Web of Sciеnce, Sciеnce Direct were analyzed for the queries «urates», «gout», «uric acid», «purine metabolism», «hyperuricosuria», «treatment of urate nephrolithiasis», «luteolin; quercetin», «Smilax riparia». Results. Urates are formed as a result of the metabolism of purine bases, two-thirds of which are excreted with urine. The most common form of purine dysmetabolism is urate nephrolithiasis, which accounts for up to 10% of all forms of kidney stone disease. The main risk factors include low urinary pH, decreased urine output and hyperuricosuria. Treatment options for such stones depend on the size, chemical composition, location, and concomitant diseases. The main methods of treatment are conservative therapy and surgical interventions. Conclusions. Since the available conservative therapy may not be suitable for all patients, and surgical intervention carries certain risks, a unique herbal complex «Uralix®» was created to treat patients with urate stones in the kidneys and urinary tract. Its components luteolin, quercetin and sarsaparilla extract reduce uric acid levels and improve renal function in urate nephropathy.
Surgical treatment of upper urinary tract obstruction in tuberculosis of the urinary system
Authors:   «Hospital for War Veterans» of the Rostov Region, Volkov A.A. ,   Rostov-on-Don, Russia, Budnik N.V. ,   «Hospital for War Veterans» of the Rostov Region; Rostov-on-Don, Russia, Zuban O.N. ,   «Moscow Scientific and Practical Center for Combating Tuberculosis of the Moscow City Health Department»; Moscow, Russia;
Published: September 2021

Introduction. Currently, the basis for effective treatment of urinary tuberculosis (UT) is a combination of specific chemotherapy with reasonable surgical intervention and strict follow-up of the patient. Materials and methods. This literature review presents the evolution of methods of surgical treatment of renal and upper urinary tract tuberculosis over of 127 sources found for the review, 63 were selected. Results. Since UT is a very slowly progressive disease with minimal and imperceptible symptoms, often leading to irreversible organ damage, up to 75% of patients with this pathology undergo surgery. As follows from the results of recent studies, the emphasis of surgical treatment is increasingly shifting from ablative and organ-carrying techniques to reconstructive operations. Surgery for upper urinary tract tuberculosis continues to develop, but its results in advanced cases of destruction of renal tissue often remain unsatisfactory. Conclusions. The search for new methods of reconstructive interventions, the purpose of which is to preserve functioning renal-ureteral units and improve the quality of life of patients, remains relevant.
The specificity of the psychological functioning of patients with interstitial cystitis
Authors:   Humanitarian Institute. P.A. Stolypin, Melekhin A.I. ,   Moscow, Russia
Published: September 2021

Introduction. The use of psychotherapeutic strategies may be preferable for patients with interstitial cystitis, who do not respond to psychopharmacotherapy and even after somatotropic therapy. therapy, surgical interventions continue to experience uncomfortable sensations. However, many urologists, given the presence of the psychosocial etiology of cystitis in some patients, continue to advocate surgical treatment. Goal. Familiarizing urologists, gynecologists, and mental health professionals with the fact that cystitis consists of heterogeneous subtypes with corresponding pathogenic pathways, comorbid mental disorders, and emotional characteristics. Among these subtypes, the psychosocial phenotype should be distinguished, which has its own specifics, psychodynamics and requires appropriate complex treatment tactics. Materials and methods. 35 women from 25 to 48 years old suffering from recurrent cystitis for 7-12 years and 35 women without urological disorders. The following diagnoses are observed in patients: somatoform autonomic dysfunction of the genitourinary system (F45. 34); psychological factors in chronic recurrent cystitis (F54); recurrent depressive disorder, an episode of moderate severity (F33.1). The patients were examined using the questionnaire of the severity of psychopathological symptoms (SCL-90-R) and the scale of diagnosis of early maladaptive schemes (YSQ S3R). Results. The psychosocial phenotype of cystitis is represented by high somatization, the presence of obsessive-compulsive traits, interpersonal sensitivity, a tendency to develop depression and an anxiety spectrum of disorders. Among the maladaptive cognitive behavioral patterns, the following predominate: negativism/ pessimism, search for approval, feeling of vulnerability, lack of self-control, submission, self-sacrifice, feeling of abandonment and instability, distrust of other people. Conclusion. In addition to psychopharmacotherapy for the treatment of anxiety and depressive symptoms in patients with cystitis, psychotherapy aimed at minimizing difficulties in emotional awareness (alexithymia) and unresolved childhood trauma of relationships should be included in the treatment program. Multimodal psychodynamic psychotherapy and cognitive behavioral therapy can reduce symptoms, affect the immune and nervous systems, and the psychological well-being of patients with cystitis.
Examination of high-risk prostate cancer patients: real practice in Russia
Authors:   Pavlov First Saint Petersburg State, Medical University, St. Petersburg, Russia, Reva S.A. , Shaderkin I.A. ,   Institute of Digital Medicine, Sechenov University; Moscow, Russia, Zyatchin I.V. ,   Pavlov First Saint Petersburg State Medical University; St. Petersburg, Russia, Arnautov A.V. ,   Pavlov First Saint Petersburg State Medical Univer-sity, St. Petersburg, Russia, Petrov S.B. ,   N.N. Petrov Research Institute of Oncology; St. Petersburg, Russia, Shaderkina V.A. ,   Urological information portal UroWeb.ru; Moscow, Russia
Published: September 2021

Introduction. Approaches to the diagnosis and staging of localized and locally advanced high-risk prostate cancer (PCa-НR) continue to be actively researched and improved. Materials and methods. In order to understand some of the controversial and controversial issues regarding the diagnosis of PCа-НR, a survey was conducted, in which 250 specialists took part – oncourologists, urologists, andrologists, specializing in the treatment / observation of patients with prostate cancer (PCа). The survey was conducted within the urological information portal Uroweb.ru by filling out a questionnaire. Results. The results obtained indicate that the most significant differences were obtained in views on the role of positron emission tomography combined with computed tomography (PET/CT) in the primary diagnosis of non-metastatic PCа and the importance of local prevalence in determining the risk of progression, while the attitude to genetic testing, primary local staging and prognosis criteria after radical prostatectomy in the majority respondents were similar. Conclusions. Most Russian oncourologists specialists involved in the treatment of PCа do not recommend that patients with PCа-HR perform PET/CT with prostate specific membrane antigen (68Ga-PSMA) and do not prescribe geneticist consultation and genetic counseling for non-metastatic PCа. To assess the local prevalence of the process in prostate cancer, based on the results of MRI, digital rectal examination and the percentage of tumor tissue in the biopsy sample. Most specialists determine the prognosis of a patient after RP by summing up the pathomorphological (PSA + radiological diagnostics + the result of histological examination) and clinical (PSA + radiological diagnostics + biopsy) indicators, which quite correlates with the global data.
PENGARUH VARIASI WAKTU OZONISASI DAN SUHU PENYIMPANAN TERHADAP KARAKTERISTIK FISIKA, KIMIA, DAN SENSORIS PADA DAGING AYAM BROILER (Gallus domesticus)
Authors: Prabawa Sigit , Putri D. K. Ramadhanty , Kawiji Kawiji , Yudhistira Bara
Published: September 2021

Ayam broiler (Gallus domesticus) merupakan jenis ternak yang banyak dikembangkan sebagai sumber pemenuhan kebutuhan protein hewani. Namun, karena merupakan bahan segar dan memiliki kandungan air yang tinggi, daging ayam broiler rentan terhadap kebusukan yang disebabkan oleh mikroba. Perlakuan dengan ozon dan suhu penyimpanan mampu mempertahankan kualitas daging ayam ditinjau dari kualitas fisika, kimia, dan sensoris. Penelitian ini bertujuan untuk mengetahui pengaruh perlakuan ozonisasi dan suhu penyimpanan terhadap sifat fisika, kimia, dan sensoris daging ayam broiler. Variasi waktu perendaman, yaitu 5, 10, dan 15 menit, sedangkan untuk variasi penyimpanan yaitu 10°C dan -6°C. Penelitian ini dilakukan menggunakan Rancangan Acak Lengkap Faktorial (RALF) dan analisis lanjutan menggunakan DMRT. Hasil yang didapatkan adalah perlakuan ozon dan suhu beku efektif dalam mengurangi nilai drip loss namun meningkatkan susut masak, menurunkan atribut warna, mengurangi nilai aw, mempertahankan nilai pH, mempertahankan laju kenaikan TBARS dan TVB-N mempertahankan nilai kesukaan konsumen. Perlakuan paling efektif untuk daging ayam yaitu dengan perendaman selama 15 menit dan penyimpanan dengan suhu -6°C mampu mempertahankan drip loss, aw, pH, TBARS, TVB-N, dan sensoris dari daging ayam.
OPEN and CLOSED state of SPIKE SARS-COV-2: relationship with some integrin binding. A biological molecular approach to better understand the coagulant effect
Authors: Luisetto M , Khaled Edbey , Mashori GR , Yesvi AR , Latyschev OY
Published: September 2021

Related the physio-pathological process of COVID-19 disease it is interesting to focus to the aspect. Played by interaction of Sars-Cov-2 protein with integrins of human epithelial pulmonary cell. A bio molecular approach help in to deeply verify the involved factors and the results of this Activation RGD mediated. Of Great interest also the relationship with some vaccine strategy followed by the various pharmaceutical industry. The results of this work will be useful to think modification in some vaccine increasing the global safety and related some rare ADR.
Laparoscopic anterior transgastric cystogastrostomy for the treatment of pancreatic pseudocysts
Authors: Fahri Yetisir , Kerim Güzel
Published: September 2021

Introduction: Pancreatic pseudocysts (PPs) are mostly delayed complications of acute or chronic pancreatitis and trauma. Pancreatic pseudocysts are usually managed by supportive medical treatment without surgical procedure. All the surgical interventions (percutaneous, endoscopic or surgical approaches) are based on the location, size, symptoms, complications of the pancreatic pseudocyst and medical condition of the patients. Recently, laparoscopic cystogastrostomy has become most appropriate approach especially for retrogastric pancreatic pseudocysts. In this study, we would like to report results of laparoscopic anterior transgastric cystogastrostomy by using linear articulated endo GIA stapler (Covidien medium thick purple) and versa-lifter (versa lifter®, laparoscopic retractor, manufactured by protomedlabs, France) in 14 pancreatic pseudocysts patients. Methods: We retrospectively analyzed data of patients with pancreatic pseudocysts treated by laparoscopic anterior transgastric cystogastrostomy from September 2010 to October 2014. All of the patients were controlled for the recurrence of pancreatic pseudocysts in February 2017. Results: 14 patients with pancreatic pseudocysts were managed by laparoscopic anterior transgastric cysto-gastrostomy. Conversion was performed in only one patient (7%). There were no symptoms and signs of recurrence of pancreatic pseudocyst during on average 43.6 months follow up time. Conclusion: Laparoscopic cystogastrostomy by using articulated linear endo-GIA stapler and versa-lifter is a safe and effective method for management of appropriate retro-gastric pancreatic pseudocysts.
Hyperparathyroidism in celiac disease: A case study from UAE
Authors: Makki H Fayadh , Salim Awadh , Loai El Kiwisney , Abdul Hadi Quadri , Prasad K Shetty , Mervat Naguib
Published: September 2021

Celiac disease affects 1% of the world population; however it is under diagnosed in UAE. The disease has many clinical manifestations, ranging from severe malabsorption to minimally symptomatic or non-symptomatic presentation. Hypocalcaemia is a common finding in celiac disease and could be the only presentation of the disease; however hypercalcemia has been previously reported in patients with celiac disease either due to primary hyperparathyroidism or tertiary hyperparathyroidism due to prolonged hypocalcaemia. A normal calcium level on the other hand in patients with untreated celiac disease who also have primary hyperparathyroidism can be due to interplay of these two conditions and may delay the diagnosis of primary Hyperparathyroidism. We report the very first case from our practice in UAE with untreated celiac disease and normal calcium level at presentation, where a diagnosis of primary hyperparathyroidism was not entertained initially. Patient went on gluten free diet which then caused normalization of intestinal abnormalities and likely calcium absorption manifesting as hypercalcemia on subsequent labs. This led to further work up and finally the diagnosis of Primary hyperparathyroidism due to parathyroid adenoma.
A novel case of an infantile fibrosarcoma-like tumor with KIAA1549-BRAF translocation and an oncogenic NF2p.Q459* SNV with potential clinical significance
Authors: Anita Nagy , Consolato M Sergi , Joseph de Nanassy , Lesleigh S Abbot , Anthony Arnoldo , Cynthia Hawkins , Bo-Yee Ngan
Published: September 2021

We report a case of a right gluteal mass from the sacroiliac joint to the knee of an infant girl. Biopsy showed histopathological features similar to infantile fibrosarcoma (IFS). However, unlike most IFS, no ETV6-NTRK3 fusion gene abnormality was detected. Molecular analysis with TruSight RNA Pan-Cancer Panel detected the presence of KIAA1549-BRAF translocation and an oncogenic NF2p.Q459* SNV with potential clinical significance. A review revealed that the combination of this patient’s tumor site with the presence of a KIAA1549-BRAF translocation abnormality and an accompanying single nucleotide variant has not been previously described. The detection of this translocation abnormality raises the possibility that the spindle cell tumors in infants with an absence of the ETV6-NTRK3 fusion gene abnormality might have a distinct pathogenetic mechanism different from the previously known IFS and congenital mesoblastic nephroma. Furthermore, the discovery of BRAF translocation and its aberrant signaling of the mitogen-activated protein kinase (MAPK) pathway in this tumor contributes to the promise of clinical benefit of using the MEKi trametinib for the treatment of progressive disease that is refractory to conventional chemotherapy.
Comparative analysis of cesarean section using the Robson's Ten-Group Classification System (RTCGS) in private and public hospitals, Addis Ababa, Ethiopia
Authors: Endalkachew Mekonnen Assefa , Adem Janbo , Yirgu Ghiwot
Published: September 2021

Objectives: We analyzed the indications of cesarean section (CS) using Robson Ten-Group. Classification Systems (RTGCS) and comparison between private and public health facilities in Addis Abeba hospitals, Ethiopia, 2017. Methods: Facility-based retrospective cross-sectional study was carried out between January 1 and December 31, 2017, including 2411 mothers who delivered by CS were classified using the RTGCS. Data were entered into SPSS version 20 for cleaning and analyzing. Binary logistic regression and AOR with 95% CI were used to assess the determinants of the CS. Results: The overall CS rate was 41% (34.8% and 66.8% in public & private respectively, p < .0001). The leading contributors for CS rate in the private were Robson groups 5,1,2,3 whereas in the public 5,1,3,2 on descending order. Robson group 1 (nulliparous, cephalic, term, spontaneous labor) and group 3 [Multiparous (excluding previous cesarean section), singleton, cephalic, ≥ 37 weeks’ gestation& spontaneous labor], the CS rate was over two-fold higher in the private than the public sector. Women in Robson groups 1, 2, 5 & 9 are two and more times higher for the absolute contribution of CS in private than public. The top medical indications of CS were non-reassuring fetal status (NRFS, 39.1%) and repeat CS for previous CS scars (39.4%) in public and private respectively. Mothers who delivered by CS in private with history of previous CS scar (AOR 2.9, 95% CI 1.4-6.2), clinical indications of maternal request (AOR 7.7, 95% CI 2.1-27.98) and pregnancy-induced hypertension (AOR 4.2, 95% CI 1.6-10.7), induced labor (AOR 2.5, 95% CI 1.4-4.6) and pre-labored (AOR 2.2, 95% CI 1.6-3.0) were more likely to undergo CS than in public hospital. Conclusion: The prevalence of CS was found to be high, and was significantly higher in private hospitals than in a public hospital. Having CS scar [having previous CS scar, Robson group 5(Previous CS, singleton, cephalic, ≥ 37 weeks’ gestation) and an indication of repeat CS for previous CS scar] is the likely factor that increased the CS rate in private when compared within the public hospital. Recommendation: It is important that efforts to reduce the overall CS rate should focus on reducing the primary CS, encouraging vaginal birth after CS (VBAC). Policies should be directed at the private sector where CS indication seems not to be driven by medical reasons solely.
Leiomyosarcoma in pregnancy: Incidental finding during routine caesarean section
Authors: Toon Wen Tang , Phoon Wai Leng Jessie
Published: September 2021

Uterine leiomyosarcoma (LMS) is uncommon tumour arising from the female reproductive tract. Incidence of LMS in pregnancy is extremely rare, with only 10 cases reported thus far in medical literature. We present a case of myomectomy performed during elective caesarean section for breech presentation, due to its easy accessibility and well contracted uterus. Subsequent histology revealed LMS on final specimen. Patient subsequently underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy. No chemotherapy was given as she opted for close clinical- radiological monitoring instead. This case report highlights the importance of discussion with patients regarding the risk of occult malignancy in a fibroid uterus. Appropriate management of uterine leiomyosarcoma in pregnancy remains unclear. Consideration of removing an enlarging leiomyoma during caesarean section might be ideal in view of its malignant potential, just like in this case; however, location of the tumour and risk of bleeding needs to be weighed. Ultimately, management of such cases needs proper discussion between obstetrician and the patient.