bluuebunny/crossref_metadata_2025 huggingface dataset:
Structural Violence and its Effects on Children Living in War and Armed Conflict Zones: A Palestinian Perspective
Authors: Tanous Osama
Published: August 2021

The recent events in Palestine–Israel once again have brought anger and frustration to people inside and outside the medical community. Especially for the pediatric community, the recent wars’ toll of at least 67 children in the Gaza Strip and two children in Israel killed warrants attention. Armed conflicts have both direct effects on children's physical health and indirect harms through toxic stress and deprivation. During these troubling times, when civilians, including children, are dying and being mutilated because of conflict, it is crucial to understand the role of structural violence in perpetuating immediate violence. This article will shed light on the historical context of the recurrent wars and military aggressions in Palestine–Israel and contextualize them from a broader public health perspective.
Atomic Ambiguity: Event Data Evidence on Nuclear Latency and International Cooperation
Authors: Mattiacci Eleonora , Mehta Rupal N. , Whitlark Rachel Elizabeth
Published: August 2021

How does dual-use technology influence cooperation? This study explores how the development of nuclear latency (the technological precursors to nuclear weapons) affects U.S. cooperative overtures toward its possessors. We argue that the ambiguous nature of nuclear latency creates uncertainty about the intentions of its possessors and impacts cooperation. Using event data, we find that a state’s possession of overt lab-scale enrichment and reprocessing facilities is significantly correlated with greater cooperative overtures from the United States toward that country. These overtures may serve as effective tools to counter nuclear proliferation among these states. Yet, when latent states engage in a concerted effort to keep their facilities secret, both at the lab and a more advanced “pilot” stage, this relationship is reversed. These results carry important implications for the impact of emerging, dual-use technologies on international security broadly.
Research on the dynamic hammering method for identifying weak parts in cantilever structures
Authors: Guo Tieneng , Meng Lingjun , Zhou Cheng , Hua Xu
Published: August 2021

Identification of the vulnerabilities in the structural stiffness is one of the most crucial issues in improving this property of machine tools. In this paper, the Flexibility Matrix Diagonal element method, based on hammer testing, is proposed as an effective approach to identifying the stiffness weakness of cantilever structures. To verify the proposed method, the element stiffness weakening is used to simulate the weak parts regarding stiffness. Several scenarios, with single and multiple weakness points, including various noise levels, are studied, using finite element simulations. Next, a novel method, to measure the accuracy of the algorithm and quantify the weakness level, under noise conditions, is proposed. The advantage of this method, compared to the ones based on Flexibility Difference Method, is the higher identification accuracy under noise interference. Finally, the cantilever beam with elastic support is experimentally studied. The natural frequencies and modal shapes are obtained, according to the singular value decomposition method, to establish the flexibility matrix. In addition, using only the lowest three modes, a series of numerical examples and experiments are provided, to illustrate the validity and the considerable practical engineering value of the method.
Spatial and social disparities in the decline of activities during the COVID-19 lockdown in Greater London
Authors: Trasberg Terje , Cheshire James
Published: August 2021

We use data on human mobility obtained from mobile applications to explore the activity patterns in the neighbourhoods of Greater London as they emerged from the first wave of COVID-19 lockdown restrictions during summer 2020 and analyse how the lockdown guidelines have exposed the socio-spatial fragmentation between urban communities. The location data are spatially aggregated to 1 km2 grids and cross-checked against publicly available mobility metrics (e.g. Google COVID-19 Community Report, Apple Mobility Trends Report). They are then linked to geodemographic classifications to compare the average decline of activities in the areas with different sociodemographic characteristics. We found that the activities in the deprived areas dominated by minority groups declined less compared to the Greater London average, leaving those communities more exposed to the virus. Meanwhile, the activity levels declined more in affluent areas dominated by white-collar jobs. Furthermore, due to the closure of non-essential stores, activities declined more in premium shopping destinations and less in suburban high streets.
Becoming the kind of doctor that you want to be. A qualitative study about participation in Balint group work
Authors: Ryding Elsa Lena , Birr Anders
Published: August 2021

Objective

Although wide-spread and appreciated, the benefit of Balint group work has been difficult to determine. Qualitative studies provide new angles for research. The aim of this study is to explore how participants in a Balint group for at least 1.5 years experienced the group work and how they were affected by their participation.

Method

Focus group interviews were conducted with a total of 19 members of four different Balint groups. The participants were experienced residents or younger specialists in general practice as well as from hospital specialities. A thematic analysis was performed.

Results

The main themes that emerged were: Investigating emotions, Development of the physician’s identity as well as Safety in the group and with the leader. The participants reported relief from stress as well as increased ability to understand the emotional side of patient encounters. They struggled to find their identity as doctors and specialists, often gaining a sense of pride in their work and becoming more secure. The group with a certified Balint leader felt like a safe place.

Conclusions

For younger doctors, participation in a Balint group for at least 1.5 years can help them build their professional identity by means of a deeper understanding of doctor-patient relationships. The role of Balint group work in relation to professional identity warrants further study.
Hazardous Duty: Investigating Resistance to Police at the Point of Arrest Among Incarcerated Military Veterans
Authors: Morgan Mark A. , Logan Matthew W. , Arnio Ashley N.
Published: August 2021

The link between military service and crime has been a subject of investigation for several decades. Although research has examined the likelihood of arrest, incarceration, and recidivism across military cohorts, relatively little is known about the circumstances surrounding police contact and suspect behavior at the exact moment of arrest. This is a critical oversight given that what transpires during an arrest can have a marked impact on downstream criminal justice outcomes, including access to diversionary programming like veterans treatment courts. Using a nationally representative survey of prison inmates, this study analyzes veteran and nonveteran self-reports of their arrest controlling for a host of relevant demographic, mental health, and criminal history variables. Findings indicate that veterans are significantly less likely to resist the police at arrest. These results provide further support to the sentiment that military culture and training can have a lasting behavioral influence on those who experience it.
Investigation of contribution of number of trials in Monte Carlo simulation for uncertainty estimation for a pressure balance
Authors: Singh Jasveer , Bura Neha , Kaushik Kapil , Kumaraswamidhas Lakshmi Annamalai , Dilawar Sharma Nita
Published: August 2021

It is well established that the estimation of measurement uncertainty is vital for the validation of any measurement and is an essential parameter of quality assurance. Apart from the conventional technique of law of propagation of uncertainty (LPU), which has many limitations, Monte Carlo simulation (MCS) technique has become an essential tool for the estimation of measurement uncertainty in various fields of metrology. The most critical factor in MCS is the generation of random numbers of the input quantities according to their probability distributions. The number of Monte Carlo trials to generate these random numbers significantly affects the results. In particular, the required number of trials is also affected by the parameter for which the uncertainty is to be estimated. Hence, in the current paper, the effect of selection of the number of trials on the random number generation and the resulting output in terms of standard deviation (SD) is investigated for the uncertainty in the effective area of a pneumatic reference pressure standard (NPLI-4) at the CSIR-National Physical Laboratory of India. The simulation results thus obtained are compared amongst themselves, with an adaptive approach as well as with the experimental results. The outcomes are analyzed and discussed in detail.
Validity and Reliability of the French Short Version of the Questionnaire of Olfactory Disorders-Negative Statements (sQOD-NS)
Authors: Leclercq Céline , Chiesa-Estomba Carlos M. , Horoi Mihaela , Le Bon Serge D. , Hans Stephane , Distinguin Lea , Chekkoury-Idrissi Younes , Circiu Marta P. , Khalife Mohamad , Saussez Sven , Lechien Jérôme R.
Published: August 2021

Objective:

To develop a French Short Version of the Questionnaire of Olfactory Disorders-Negative Statements (Fr-sQOD) to assess the quality of life impairments of patients with olfactory dysfunction (OD).

Methods:

Patients with OD and controls were enrolled from 2 academic centers. Individuals completed the Fr-sQOD, an OD visual analog scale severity, and the French version of the sinonasal outcome tool-22 (SNOT-22). Cronbach α was used to measure the internal consistency of Fr-sQOD. The reliability and the external validity of Fr-sQOD were assessed through a test–retest approach and by correlating Fr-sQOD with SNOT-22 scores, respectively. The external validity was assessed by correlation analysis between Fr-sQOD and the result of an assessment of the severity of OD on a visual analog scale.

Results:

Eighty patients completed the evaluations. The internal consistency was adequate (Cronbach α .96), and the test–retest reliability was high in the entire cohort (rs = 0.877, P < .001). The correlation between Fr-sQOD total scores and the severity of OD was moderate but significant (rs = −0.431; P = .001) supporting an acceptable external validity. Patients with OD had a significantly higher score of Fr-sQOD than healthy individuals ( P < .001), indicating a high internal validity.

Conclusion:

The Fr-sQOD is a reliable and valid self-administered tool in the evaluation of the impact of OD on quality of life of French-speaking patients.
Treatment of Postinfectious Olfactory Dysfunction Using Corticosteroids
Authors: Duan Hong-Gang , Ji Fang , Yan Mao-Xiao
Published: August 2021

Objective:

This study aimed to analyze the efficacy of different doses and forms of corticosteroids in the treatment of postinfectious olfactory dysfunction and to specify the factors related to the curative effects.

Methods:

The medical records of patients diagnosed with postinfectious olfactory dysfunction from January 2018 to May 2019 were reviewed. All patients received different doses of oral corticosteroids for 12 days or inhaled corticosteroids for 1 month.

Results:

A review of the records of 43 patients showed that the mean follow-up time was 6.66 months, and the overall effective rate of treatment was 48.8%. Postinfectious olfactory dysfunction exhibited distinct seasonality, with the highest incidence in March. The curative effect was significantly related to the olfactory discrimination threshold at the first consultation ( P = .022), but not significantly associated with age ( P = .325), sex ( P = .924), duration of disease ( P = .526), follow-up time ( P = .489), or treatment program ( P = .330).

Conclusions:

Different doses and forms of corticosteroids showed no significant difference in the therapeutic effect on postinfectious olfactory dysfunction. The olfactory discrimination threshold at the first consultation was the most important factor influencing the prognosis.
A Preliminary Report on the Correlation Between Nasal Function and the Different Phases of the Nasal Cycle
Authors: Li Yihan , Yu Chenjie , Li Peizhong , Qian Xiaoyun , Song Panpan , Gao Xia
Published: August 2021

Objective:

To explore whether the different phases of the nasal cycle have a significant effect on nasal temperature, the nasal mucosal clearance rate, and levels of nasal nitric oxide (nNO) and to investigate the correlation between these nasal conditions.

Methods:

The study participants were divided into 2 groups: the control group and the rhinitis group. The participants’ nasal temperature, cilia clearance rate, and nNO levels were measured during different phases of the nasal cycle (the congestion phase and decongestion phase) in the control group and before and after undergoing inferior turbinate ablation in the rhinitis group.

Results:

The temperature of the nasal cavity in the control group was significantly higher in the congestion phase than in the decongestion phase ( P = .0025), while in the rhinitis group, the temperature of the nasal cavity decreased significantly after inferior turbinate ablation ( P = .001). In the control group, the nasal mucosa clearance time was significantly shorter in the congestion phase than in the decongestion phase ( P = .001), and in the rhinitis group, the clearance time of the nasal mucosa was significantly shortened after the operation ( P = .0025). In the control group, the levels of nNO were significantly higher in the congestion phase than in the decongestion phase ( P = .025), while in the rhinitis group, nNO levels decreased significantly after the operation ( P = .005).

Conclusion:

The function of the nasal cavity changes in different phases of the nasal cycle. Therefore, when evaluating the impact of various factors on nasal function, factors associated with the nasal cycle should also be considered. Inferior turbinate plasma ablation can improve the ciliary function of the nasal mucosa, reduce the temperature of the nasal cavity, and reduce nNO levels.
Clinical Characteristics of Older Adults Seeking Hypoglossal Nerve Stimulation for the Treatment of Obstructive Sleep Apnea
Authors: Dzierzewski Joseph M. , Soto Pablo , Vahidi Nima , Nord Ryan
Published: August 2021

Objectives:

Obstructive sleep apnea (OSA) is a common sleep disorder with numerous clinical correlates. Although effective treatments abound, patient acceptance and adherence is low. Hypoglossal nerve stimulation (HNS) is a surgical treatment alternative for the treatment of OSA; however, the demographic and clinical characteristics of individuals seeking HNS are not well categorized. This study sought to determine the clinical characteristics of older adults seeking HNS for the treatment of OSA.

Methods:

Self-report questionnaires were administered to all patients older than 50 years seeking a HNS consultation at a large university medical center. Questionnaires included validated National Institutes of Health Patient-Reported Outcomes Measurement Information System (NIH PROMIS) measures of physical functioning, sleep-related impairment, cognitive abilities, depression, anxiety, and anger along with the Information extracted from electronic medical records included age, sex, race, and apnea–hypopnea index (AHI).

Results:

Patients included 113 adults (mean age 63.30 years, 57% male, 79% white) with severe OSA (AHI = 33.91, standard deviation = 20.63). Overall, 88% of patients reported elevated insomnia symptoms, 30% reported mild difficulty with physical functioning, and 36% indicated that they had experienced moderate-severe daytime impairments attributed to poor sleep. Additionally, we found 28% of sampled individuals reported moderate-severe depressive symptomology, over 19% reported moderate-severe anxiety, and over 17% reported moderate to severe anger issues. Approximately, 38% of the sample reported moderate to severe cognitive difficulties.

Conclusions:

The aim of the study was to better understand the clinical characteristics of older patients with OSA seeking HNS treatment. Utilizing NIH PROMIS questionnaires, we identified unique clinical and psychosocial correlates in this sample, which included higher rates of insomnia symptoms, physical dysfunction, cognitive deficits, and depressive symptoms than the general population. Future studies will be needed to investigate these relationships more thoroughly and throughout the course of the treatment.
Science or Ignorance of Animal Welfare? A Case Study: Scientific Reports Published in Preparation for the First European Directive on Animal Welfare (1979-1980)
Authors: Ducourant Sam
Published: August 2021

In 1979, the Council of the European Communities declared its intention to ban battery cages for laying hens; one year later, everything about the ban is forgotten. During this preparatory year (1979-1980), all that happened is the publication of scientific reports, that is, attempts at producing knowledge as a basis for and justification of the ban decision. This paper aims at understanding to what extent ignorance and doubt were produced instead. By examining the reports, I demonstrate that there are three interrelated levels of ignorance production: (1) the missions given by the Commission to scientists were ambiguous, (2) questions inherent to animal welfare sciences, such as the significant variability of their measures and results, lead to a systematic standardization, and (3) the battery cage works as a techno-scientific promise and an “obligatory passage point” where scientists and industry meet. Disciplinary identity issues therefore lead scientists to adopt a double standard about the welfare of laying hens.
Global Incidence of Sporadic Vestibular Schwannoma: A Systematic Review
Authors: Marinelli John P. , Beeler Cynthia J. , Carlson Matthew L. , Caye‐Thomasen Per , Spear Samuel A. , Erbele Isaac D.
Published: August 2021

Objective

Ubiquitous throughout the literature and during patient counseling, vestibular schwannoma is often quoted to affect about 1 per 100,000 people. Yet, reports from distinct international populations suggest that the incidence is likely much higher. The objective of the current work was to systematically characterize the global incidence of sporadic vestibular schwannoma.

Data Sources

Scopus, Embase, and PubMed.

Review Methods

Population‐based studies reporting incidence rates of sporadic vestibular schwannoma between January 2010 and August 2020 were searched with language restrictions requiring reports to be published in Chinese, English, German, Italian, or Spanish. The protocol was registered with PROSPERO (CRD42021228208) prior to commencement of data collection. PRISMA guidelines for transparent reporting of systematic reviews were followed.

Results

Among 424 citations, 6 publications covering 4 distinct populations from Denmark, the Netherlands, Taiwan, and the United States met inclusion criteria. Most recent incidence rates of among all ages ranged between 3.0 and 5.2 per 100,000 person‐years. Highest incidence rates were reported among patients aged ≥70 years, peaking at 20.6 per 100,000 person‐years. One study from the United States reported the incidence of asymptomatic, incidentally diagnosed tumors at a rate of 1.3 per 100,000 person‐years from 2012 to 2016.

Conclusions

Recent international incidence rates of sporadic vestibular schwannoma exceed the commonly quoted “1 per 100,000” figure by up to 5‐fold among all ages and by up to 20‐fold among age groups at highest risk. Based on modern incidence rates, the lifetime prevalence of developing sporadic vestibular schwannoma likely exceeds 1 per 500 persons.
Getting Better? Hegemonic, Negotiated and Oppositional Uses of Instagram for Mental Health Support
Authors: Lindgren Simon , Johansson Anna
Published: August 2021

By analysing 600 Instagram posts that use mental health related hashtags, this article investigates how mental health communication and support practices are enacted on Instagram, and how such practices relate to the perceptible affordances and hegemonic uses of the service. The article demonstrates how Instagram tends to privilege casual snapshots of individual recovery, in line with broader discourses of positive thinking and individual responsibility. Whereas this hegemonic way of using the service may be functional for many users, three examples of negotiated and oppositional use are also discussed in the article: motivational picture quotes, text-rich posts, and non-recovery oriented posts. It is suggested that different ways of imagining and approaching the affordances of the service engender different patterns of support practices.
Rehabilitation in Dementia
Authors: Gupta Anupam , Prakash Naveen B. , Sannyasi Gourav
Published: August 2021

Dementia is an eurodegenerative disorder, which causes significant disability, especially among the elderly population worldwide. The affected person shows a progressive cognitive decline, which interferes with the independence in performing the activities of daily living. Other than the cognitive domain, the patient tends to have neuropsychiatric, behavioral, sensorimotor, speech, and language-related issues. It is expected that the global burden of the disease will rise with more people entering the geriatric age group. By 2050 close, to 140 million people will be living with one or the other type of dementia. Alzheimer’s disease contributes to more than 60% of cases worldwide, followed by vascular dementia.

Pharmacotherapy has a limited role to play in the treatment, and at present, no drug is available, which can halt or reverse the progress of the disease. World Health Organization has mandated rehabilitation as a core recommendation in the global action plan on the public health response to dementia. Rehabilitation services are widely recognized as a practical framework to maximize independence and community participation in dementia care. The rehabilitation program is customized to achieve the desired goals, as each person has different experiences, preferences, motivations, strengths, and requirements based on type, course, and severity of the illness. It is an interdisciplinary-team approach with the involvement of several health care professionals. This article reviews the existing literature and outlines the effective rehabilitation strategies concisely in dementia care.
Causal Entropic Forces, Narratives and Self-organisation of Capital Markets
Authors: Bocher Romain
Published: August 2021

The intersubjective markets hypothesis is revisited with respect to causal entropic principles. While the financial system is assumed to naturally evolve towards uncertainty, a spontaneous and unstable form of order emerges, thanks to narratives, leading to self-organised criticality. This article also includes a discussion about main hypotheses in finance, about the link between volatility spikes and entropy, and, finally, about the important role of narratives as forms of collective intelligence.

JEL: D40, D50, D53, D70, D80
The (Plural) Nation as a Community of Judges: A Knotty South Asian Predicament
Authors: Menski Werner
Published: August 2021

M.K. Raghavendra, The Hindu Nation. A Reconciliation with Modernity (New Delhi: Bloomsbury India, 2021), ix + 310 pp.
Why we need an internationally shared rehabilitation definition for clinical research purposes
Authors: Negrini Stefano , Levack William Mark Magnus , Meyer Thorsten , Kiekens Carlotte
Published: August 2021

Purpose:

Responding to a recent editorial arguing against defining rehabilitation, we discuss the reasons for developing a classification of rehabilitation for research purposes, its philosophical background and some of the possible risks.

Why define:

Science requires the definition and classification of phenomena to allow replication of experiments and studies, and to allow interpretation and use of the findings. As understanding increases, the definitions can be refined. Defining rehabilitation does run the risk of excluding some interventions or practices that are either considered rehabilitation (perhaps wrongly) or are rehabilitation interventions; when identified, these errors in definition can be remedied. Defining rehabilitation for research purposes should not inhibit but could (possibly) orient research.

Risk of not:

Without a definition, rehabilitation will remain in a permanent limbo. Experts will (apparently) know what it is, while others are left guessing or failing to comprehend or recognise it. This uncertainty may reassure some people, because all possible interventions are included; we argue that it downgrades the understanding of our field because interventions that are not rehabilitation are, nonetheless, called rehabilitation. In an era of international collaboration, and of undertaking systematic reviews with metanalysis, we need a shared definition.

Conclusion:

Terminology is often controversial, but definition enables progress in understanding such that terms themselves can evolve over time.
Ultrasound-stimulated microbubbles enhances radiosensitivity of ovarian cancer
Authors: Ba Shuang , Yu Ming
Published: August 2021

Background

Radiation therapy is regarded as an effective treatment for early ovarian cancer (OC). However, due to radiation resistance caused by DNA double-strand breaks (DSBs) and angiogenesis, the efficacy of radiotherapy for advanced OC is limited and controversial.

Purpose

To explore whether ultrasound-stimulated microbubbles (USMBs) can enhance the radiosensitivity of OC.

Material and Methods

OC cells (ES-2) were respectively irradiated with 5-Gy and 10-Gy radiation doses with or without exposure to USMB. Methyl thiazolyltetrazolium (MTT) and colony-formation assays were conducted to detect the viability and proliferation of ES-2 cells after USMBs and ionizing radiation (IR) treatment. Immunofluorescence assays were conducted to examine levels of gamma-H2A histone family member X (γ-H2AX), an indicator for DSBs. Flow cytometry analyses were carried out to assess the apoptosis of ES-2 cells. The angiogenic activity of human umbilical vein endothelial cells (HUVECs) was measured by tube formation assays.

Results

USMBs enhanced IR-induced suppressive effect on the viability and proliferation of OC cells. The protein levels of phosphorylated γ-H2AX and CHK1 were significantly upregulated after IR treatment and further enhanced by USMBs. In addition, USMBs enhanced the promotion of IR-mediated OC cell apoptosis. The inhibitory effect of IR on angiogenesis was further enhanced by USMBs, and protein levels of AT1R, VEGFA, and EGFR were downregulated by IR in a dose-dependent way and then enhanced by USMB treatment in HUVECs.

Conclusions

USMB exposure significantly enhances the radiosensitivity of OC by suppressing cell proliferation, promoting OC cell apoptosis, and inhibiting angiogenesis.
Infectious laryngotracheitis of chickens: Pathologic and immunohistochemistry findings
Authors: Carnaccini Silvia , Palmieri Chiara , Stoute Simone , Crispo Manuela , Shivaprasad H. L.
Published: August 2021

Infectious laryngotracheitis (ILT) is an important upper respiratory disease of chickens. Gross and histologic lesions of ILT in chickens are compared to immunohistochemistry to evaluate the diagnostic test sensitivity. A total of 31 separate ILT-confirmed necropsy submissions (12 commercial meat-type flocks, 13 egg-type producers, and 6 backyard flocks) were arbitrarily selected. Each submission ranged from 1 to 18 birds, for a total of 246 chickens. Cases with available formalin-fixed tissues were selected to include a range of bird production types, ages, clinical histories, and severity of macroscopic and histologic lesions. Macroscopic findings in the respiratory tract varied from increased mucus (55.6%) to fibrinonecrotic exudate (20.3%) and hemorrhages in the larynx and trachea (13.0%). Syncytia with intranuclear inclusion bodies were present in the respiratory tract epithelium with or without hemorrhages. Sections of conjunctiva, sinus, larynx, trachea, lung, and air sac were analyzed by immunohistochemistry (IHC) to detect gallid alphaherpesvirus 1 (GaHV-1) antigen. Positive immunolabeling was detected in the cytoplasm and nuclei of syncytia and epithelial cells in 18/22 conjunctivae (82%), 12/13 sinuses (92%), 18/22 larynxes (82%), 23/25 tracheas (92%), 10/21 lungs (57%), and 3/8 air sacs (37%). Of the 34 tissues with no visible syncytia or inclusion bodies, 8 were positive by IHC. In conclusion, IHC was useful to study the viral antigen tissue distribution and support the diagnosis of ILT when the histopathologic interpretation was doubtful.
Site-Specific Transportation Demand Management: Case of Seattle’s Transportation Management Program, 1988–2015
Authors: McKnight-Slottee Mairin , Bae Chang-Hee Christine , McCormack Edward
Published: August 2021

A central theme of U.S. transportation planning policies is to reduce single-occupancy vehicle (SOV) trips and promote transit and non-motorized transportation by coordinating land-use planning and transportation demand management (TDM) programs. Cities often implement TDM programs by intervening with new development during the municipal permit review process. Seattle’s Transportation Management Program (TMP) under a joint Director’s Rule (DR) requires a commitment from developers to adopt select strategies from six TDM element categories: program management, physical improvements, bicycle/walking programs, employer-based incentives, transit and car/vanpooling, and parking management. TMP targets new developments and requires some TDM elements, recommends others, and leaves the rest to negotiation. The result is an individualized TMP agreement that is site-specific, reflecting both city policy and developer needs. This case study presents a qualitative analysis of the guiding eight DRs and 41 site-specific TMP agreements in Seattle’s Downtown and South Lake Union (SLU) area since 1988. Overall, a content analysis of TMP documents reveals that the average number of elements adopted in an agreement falls short of requirements set by DRs (34%–61%). Major findings include developer preference toward non-traditional TDM measures such as physical improvement of frontage and urban design features, as well as parking management. High-occupancy vehicle (HOV) elements showed higher adoption rates (59%–63%) over biking/walking programs (< 1%). It is concluded that future TDM policies could benefit if future research includes examining the effectiveness of the range of management options stemming from the real estate trends toward green buildings, tenants’ values in sustainability, and city policy to reduce automobile trips.
Practical Use of Single-Case Research Design to Target Improved Behavioral Outcomes for Students With SLD
Authors: Contesse Valentina A. , Gage Nicholas A. , Lane Holly B.
Published: August 2021

Intensive academic interventions help address the learning difficulties of students with specific learning disabilities (SLDs). Challenging behaviors exhibited during instruction can have a negative impact on the overall effectiveness of an academic intervention. In addition to academic interventions, students with SLD may benefit from behavioral interventions. One method for evaluating the effect of interventions that target improved behavioral outcomes for students with SLD is single-case research design (SCRD). This article provides an overview of critical features of SCRD studies evaluating behavioral interventions with students with SLD or interventions with teachers of students with SLD. The article also examines how research decisions were made to support other researchers’ development of high-quality SCRD studies.
“I worry about this patient EVERY day”: Geriatrics Clinicians’ Challenges in Caring for Unrepresented Older Adults
Authors: Dassel Kara B. , Edelman Linda S. , Moye Jennifer , Catlin Casey , Farrell Timothy W.
Published: August 2021

Unrepresented older adults are at risk for adverse outcomes, and clinicians who care for them may face ethical dilemmas and unique challenges when making person-centered care recommendations. However, little is known about their perspectives on clinical challenges in caring for this population. An online survey was used to assess issues around providing care for unrepresented patients. Ninety-two American Geriatrics Society members working with older adults in inpatient and/or outpatient settings completed the survey. Descriptive qualitative analysis of narrative survey responses identified five broad themes: (a) health risk characteristics of patients, (b) care decisions facing the team, (c) psychosocial considerations by the team, (d) patient outcomes, and (e) burden of the provider and/or health system. These findings demonstrate that geriatrics clinicians face challenges in working with unrepresented adults in both inpatient and outpatient settings. We interpret these results in light of existing literature and propose collaborative approaches that may improve outcomes.
Lethal Violence in Brazil: A Systematic Review of Portuguese-Language Literature From 2000 to 2020
Authors: Ceccato Vania , Kahn Tulio , Vazquez Lisandra Cardoso
Published: August 2021

Reviewing national literature on homicides in Brazil, this article explores questions that relate to the nature, trends, determinants, and impact of these crimes on society, as well as interventions to combat this type of violence. The article contributes to the international literature by reviewing and critically discussing a sample of 112 theses on homicides from the Portuguese-language literature using the Brazilian Digital Library of Theses and Dissertations from 2000 to 2020. Highlighting an issue that primarily affects young, poor Black men, the article helps advocate for a better understanding of other types of lethal violence that affect women, LGBQTI and other minorities. The article calls for a better understanding of the role of the state, the police and other criminal justice actors as generators and/or controllers of violence, as well as the need for other perspectives on homicide prevention, which include the microsituational aspects of killing, organized crime, and interaction between the individual and the environment.
Challenges confronting waste pickers in Indonesia: An on-field analysis
Authors: Kristanto Gabriel Andari , Kemala Dini , Nandhita Paras AC
Published: August 2021

This article presents the informal recycling sector’s (IRS) social, economic driving factors in five cities in Indonesia and their contribution to waste management in the cities. An on-field analysis was conducted by random and incidental sampling method of questionnaire administration followed by observation. Among the respondents ( n = 178), 79% of individuals were waste pickers, 15% were small-scale waste collectors, and 6% were medium-scale waste collectors. The majority of the waste pickers sampled are male (79%). The amount of waste collected by individual waste pickers is 43.87 kg person−1 day−1, a corresponding recycling rate of approximately 12%, and an average monthly income of US$91.7. Gender differences are apparent as the male waste pickers generated higher incomes than those earned by their female counterparts (US$128.3 for men and US$69.7 for women) even as their average work hours are similar to that of the men (7.8 and 7.6 hours day−1, respectively). Economic motives are the respondents’ primary driving factors as moving to large cities accompanied by their family members. The study concluded that the IRS plays substantial contribution to waste management; further integrating them into the waste management system via IRS association, additional investment, formulation of law and policies and efforts by municipalities can give various benefits for involved stakeholders, the community and the environment. The results can serve as a significant reference for improving the solid waste recycling system and informal sector management in Indonesian cities and other developing countries.
Development of a Quality-of-Life Survey for Patients With Succinic Semialdehyde Dehydrogenase Deficiency, a Rare Disorder of GABA Metabolism
Authors: Bose Mousumi , Roullet Jean-Baptiste , Gibson K. Michael , Rizzo William B. , Mansur Hana M. , McConnell Alice , Hoffman Carolyn A. , DiBacco Melissa L. , Pearl Phillip L.
Published: August 2021

Succinic semialdehyde dehydrogenase deficiency (SSADHD), a rare disorder of GABA metabolism, presents with significant neurodevelopmental morbidity. Although there is a growing interest in the concept of quality of life through patient reports as a meaningful outcome in rare disease clinical trials, little is known about the overall impact of SSADHD from the patient/family perspective. The purpose of this study was to determine issues related to quality of life and patient/family experience through a focus group discussion with family caregivers of patients with SSADHD. The discussion included the input of 5 family caregivers, and highlighted concerns related to physical function, cognitive and intellectual function, psychological and behavioral function, social function, and family impact. These themes represent appropriate starting points in the development of a quality-of-life survey that may serve as a meaningful clinical tool in future studies of SSADHD.
Fabrication and characterization of an acellular annulus fibrosus scaffold with aligned porous construct for tissue engineering
Authors: Jin Xiaoyu , Kang Ran , Deng Rongrong , Zhao Xu , Wang Zihan , Rong Weihao , Xie Lin
Published: August 2021

Scaffolds mimicking the native annulus fibrosus (AF) extracellular matrix (ECM) structure are crucial to guide the seeding cells to regenerate aligned tissue, while fabricating such a scaffold by synthetic material is challengeable. Native acellular scaffolds derived from AF tissue certainly possess the advantages of natural structure and composition. Based on previous studies, we modified decellularization procedure and especially compared two drying methods, including gradient dehydration and freeze-drying. The decellularization process can effectively remove the host cells and antigens such as α-Gal, while maintaining the original ECM including GAG and collagen I. Compared with gradient dehydration, freeze-drying not only rendered the decellularized scaffold in dry state for storage but also gave the scaffold more aligned porous structure and hydrophilicity. And, the acellular porous scaffold manifested better capacity of supporting cell ingrowth when seeded human bone marrow mesenchymal stem cells (hBMSCs) or implanted in vivo. Furthermore, this optimized freeze-dried scaffold showed similar mechanical elastic modulus as native AF and demonstrated rare inflammatory granuloma and immune rejection as observed in HE staining and immunohistochemistry staining (IHC) of CD8 and MAC387 epitopes when implanted subcutaneously in vivo. To sum up, through our decellularization and freeze-drying procedure, an aligned porous three-dimensional scaffold derived from the natural AF ECM was successfully fabricated with good retention of ECM components and benign biocompatibility. It will be a promising scaffold for AF tissue engineering.
Transgender Polyvictimization in the U.S. Transgender Survey
Authors: Messinger Adam M. , Guadalupe-Diaz Xavier L. , Kurdyla Victoria
Published: August 2021

Relative to cisgender people, transgender individuals not only are at an elevated risk of experiencing at least one form of physical or sexual violence, but also at an increased risk of polyvictimization: that is, exposure to multiple types of violence over the life course. Given that polyvictimization increases vulnerability to adverse mental and physical health sequelae, there is a pressing need to identify which sociodemographic subgroups of transgender people are at greater risk of polyvictimization. Understanding these risk profiles will have important implications for developing transgender-specific models for violence prevention, screening, and intervention. Responding to this need in the literature, the present article offers secondary data analyses of the 2015 U.S. Transgender Survey, the largest study to-date of transgender people in the United States ( N = 27,715 transgender adults), with participants selected from all 50 states and Washington, D.C., as well as several U.S. territories and overseas military bases. Multiple variable regressions examine sociodemographic predictors of five distinct forms of violence, as well as how many of these five violence types were experienced. The examined sociodemographic predictors included gender, sexual orientation, race-ethnicity, citizenship status, ever been homeless, has a disability, transgender outness, gender visual conformity, household income, and age. The five assessed violence victimization types included intimate partner violence, nonpartner sexual assault, antitransgender family violence, antitransgender physical violence during Kindergarten through 12th grade, and past-year antitransgender physical violence. With some exceptions, results indicate that more marginalized segments of transgender communities have a greater likelihood of experiencing polyvictimization. Recommendations are discussed for future research and service provision.
Trauma-Informed Acute Care of Patients With Violence-Related Injury
Authors: Hawkins Bonnie Elizabeth , Coupet Edouard , Saint-Hilaire Sidney , Dodington James
Published: August 2021

Violently-injured individuals presenting to the emergency department (ED) have an elevated risk of repeat injury after being discharged from acute care settings and a high rate of unaddressed mental health and social needs. While there is a growing body of programmatic interventions to address these needs, including hospital-based violence intervention programs, there is a lack of data regarding physician perspectives of current practice for this patient population. Understanding current practice is critical for integrating new programs into workflow and developing evidence-based medical education to improve care. The aim of this study is to elucidate current trauma-informed care practices of emergency medicine and general surgery trainee physicians to inform future curriculum development surrounding care of violently injured patients. In this study, emergency medicine and surgical trainees with at least one year of residency experience participated in simulation-primed interviews in pairs or small groups. Interviews garnered perspectives on the physician role in treating violently injured youth, using simulation as a priming event focused on previously known patient concerns. Qualitative themes that emerged were participants (1) perceived their role as managing medical/surgical concerns and seek others to build trust and manage psychosocial and legal concerns, (2) had a high level of knowledge of ED stressors and de-escalation strategies, (3) perceived that patient distrust can negatively impact their ability to provide care, and (4) perceived that law enforcement can negatively impact care and are sometimes uncertain about how to interact with law enforcement. These findings support that medical education for providers should focus on medicolegal issues, particularly managing law enforcement presence in the ED, structural and interpersonal causes of distrust of medical providers and the medical system, and addressing postdischarge mental health and social needs.
Parental Phubbing and Children’s Social Withdrawal and Aggression: A Moderated Mediation Model of Parenting Behaviors and Parents’ Gender
Authors: Wang Xingchao , Qiao Yuran , Li Wenqing , Lei Li
Published: August 2021

The present study sought to examine whether parental phubbing was significantly related to children’s social withdrawal and aggression, and determine whether positive and negative parenting behaviors mediated this association. We further examined whether parents’ gender moderated the direct and indirect relationships between parental phubbing and children’s social withdrawal and aggression. The participants included 465 Chinese fathers and mothers from different families, and each father or mother had one child from preschool and early school aged 4–10 years. They completed the measures regarding their experience with parental phubbing, positive and negative parenting behaviors, and children’s social withdrawal and aggression. Results showed that parental phubbing was positively related to children’s social withdrawal and aggression. Positive and negative parenting behaviors significantly mediated the associations between parental phubbing and children’s social withdrawal and aggression. Furthermore, parents’ gender moderated the relationships between parental phubbing and children’s social withdrawal and aggression. Specifically, in the mediating model of positive parenting behavior, the pathways from parental phubbing to children’s social withdrawal and parental phubbing to children’s aggression were significantly different. In the mediating model of negative behavior, the pathway from negative parenting behavior to children’s social withdrawal was significantly different.
Illuminating Nursing’s Value: The 12 Anthroposophic Nursing Gestures
Authors: Kramer Michele R. , Schmiesing Laurie , von Dach Christoph
Published: August 2021

Nursing care historically has not been separated from institutional care costs. Organizations seek to quantify nursing care with no assignation of the value or uniqueness of the individual patient–nurse encounter. New models point to measuring care at this level. Nursing care encompasses tangible evidence that can be easy to quantify but, in the paradigm of healing and caring, and more specifically within the knowledge pool of holistic nursing, significant contributions are intangible and thus hard to measure. Anthroposophic nursing’s 12 nursing gestures offer an integration by making intangible nursing practice tangible. They incorporate addressing the whole person and more clearly show the caring and healing aspects of nursing care. Making such intangibles of care tangible contribute to the discussion of nursing value and how it is measured in healthcare organizations. More research is needed, however, to refine and value nursing care to more accurately reflect the connection between caring, healing, and patient outcomes.
Dynamic investigation of a spatial multi-body mechanism considering joint clearance and friction based on coordinate partitioning method
Authors: Hua Gao , Jingyu Zhai , Hao Zhang , Qingkai Han , Jinguo Liu
Published: August 2021

The dynamic response of the model, which is the series connection of a planar four-bar mechanism and a spatial RSSR mechanism, is analyzed considering revolute joint clearance and friction. A non-holonomic constraint equation is proposed to solve the Euler angles. The dynamic equations are established by combining the Lagrange equation with the modified contact model and the LuGre friction model. A dynamic solution program based on the coordinate partitioning method is designed to solve the dynamic equations. The paper verifies the correctness and applicability of the solution program by comparing the numerical calculation results with Adams simulation. Compared with the results of eccentricity, it is found that the maximum penetration is very sensitive to the change of the slider speed rather than the clearance. The equivalent damping coefficient proposed by authors not only represents whether a collision occurs, but reflects the hysteresis caused by damping. The macroscopic manifestation of the up and down oscillation of eccentricity is the swing of the contact point. Besides, the system quickly changes from the collision into the stable state due to considering friction, and the peak value of each collision reduces greatly. Therefore, when the clearance is unavoidable, the clearance joint should be coated with a material with a large friction coefficient and not easy to wear.