bluuebunny/crossref_metadata_2025 huggingface dataset:
Performance Evaluation and Cost Analysis of Photovoltaic Thermal (PVT) System Using the Triangular Shape of Absorber with Different Water-based Nanofluids as Coolants
Authors: Singh Mrigendra , Solanki S.C , Agrawal Basant , Bhargava Rajesh
Published: June 2024

The worldwide energy demand is continuously increasing, prompting experts to recommend using alternative energy sources to conserve natural gas, fossil fuels, and electricity. Photovoltaic thermal (PVT) systems emerge as a viable solution, generating electrical and heat energy simultaneously while freeing carbon dioxide (CO2) emissions. These systems offer sustainable green technology for supplying renewable electricity and heat to commercial and domestic applications. This study delves into the performance of a photovoltaic thermal (PVT) system featuring an isosceles triangular-shaped absorber design. It considers size variations of 0.02 and 0.03 m while maintaining a constant aspect ratio. Water-based nanofluids such as CuO/w, MgO/w, and ZnO/w, with a nanoparticle volume portion of 4%, alongside pure water as a coolant, are utilized with a variation of mass flow rate ranges from 0.028 kg/s to 0.11 kg/s, allowing for an exploration of its impact on performance parameters. A numerical model is established to comprehensively analyze the system's performance, applying an energy balance equation to its components. An economic analysis is also conducted to assess the system's cost-effectiveness and determine the energy payback time. Results indicate that the highest overall daily performance is achieved with ZnO/w nanofluid at a mass flow rate of 0.112 kg/s and a fluid flow channel size of 0.02 m. Comparatively, compared to other nanofluids and pure water, the average electrical, thermal, and overall performances achieved are 14.57%, 22.36%, and 36.40%, respectively. The energy payback periods are 5.5, 5.2, 5.4, and 4.8 years for CuO/w, MgO/w, ZnO/w, and Pure water, respectively. Furthermore, it is observed that a higher mass flow rate correlates with higher system performance parameters.
PV-Based Design and Evaluation of Power Electronic Topologies for EV Applications
Authors: Reddy Bondu Pavan Kumar , Reddy Vyza Usha
Published: June 2024

This study presents a unique concept for an electric vehicle (EV) charging system that is powered by photovoltaic (PV) technology. The core of the system is a modified single-ended primary inductance converter, chosen for its high efficiency, reduced switch voltage stress, and ample operating range for maximum power point tracking (MPPT). This study details the redesigned SEPIC converter architecture, including with and without the MPPT algorithm. Additionally, an optimized parameter selection, design methodology, and simulation technique are presented for analyzing converter performance in EV charging applications. Two MPPT approaches, Perturb and Observe (P&O) and incremental conductance (IC), are investigated and compared based on their impact on the converter switching time under standard solar PV panel testing conditions. To comprehensively evaluate the system's performance, a MATLAB/Simulink model is developed, simulating the charging of a 48 V, 200 Ah battery using a 2 kW solar PV input through the modified SEPIC converter and variations in the battery state of charge (SoC), battery voltage, and charging current are monitored. The simulation results demonstrate that under identical simulated conditions (10 Sec), the battery SoC increases from 50% to 50.034% without MPPT and to 50.042% with MPPT, highlighting the effectiveness of the MPPT algorithms in maximizing harvested solar energy.
Imaging Characteristics and Diagnostic Challenges of Alveolar Hydatid Disease in The Liver: A Comprehensive Analysis
Authors: Wani Maria , Muzamil Aala , Altaf Ayaan , Shaheen Feroze A
Published: June 2024

Alveolar Hydatid Disease (AHD) of the liver, primarily caused by the parasitic infection Echinococcus multilocularis, presents a formidable diagnostic challenge. This disease mimics a range of hepatic conditions, complicating accurate identification and timely treatment. Our study aimed to delineate the distinct imaging characteristics of AHD, facilitating better diagnostic accuracy. In this prospective study, we analysed the imaging results from thirty-five patients with confirmed AHD, either through pathology or serology. Utilizing contrast-enhanced Computed Tomography (CT) and Magnetic Resonance Imaging (MRI), we thoroughly evaluated the radiological signatures specific to AHD. The findings demonstrated that amorphous calcifications, a hallmark of AHD, were consistently present across all patients in CT scans. MRI revealed a predominant pattern of large solid lesions accompanied by significant cystic or necrotic components. These imaging traits are critical in differentiating AHD from other hepatic diseases, such as hepatocellular carcinoma or metastatic liver disease, which often present with similar symptoms but require vastly different treatment approaches. Our study underscores the necessity of recognizing these specific imaging patterns early in the diagnostic process, a step that is crucial for the implementation of effective treatment strategies. In conclusion, this study provides valuable insights into the imaging characteristics of AHD, highlighting the role of advanced imaging techniques in improving diagnostic accuracy. These findings are a significant contribution to the medical field, especially for radiologists and clinicians dealing with hepatic diseases, enhancing patient outcomes through precise diagnosis and timely intervention.
Methanol extract of Isodon ternifolius (D. Don) KUDO leaves has antimicrobial and antioxidant activities but no neuroprotective activity.
Authors: Hijam Aruna Chanu , Koijam Arunkumar Singh , Haobam Reena
Published: June 2024

Isodon ternifolius (D. Don) KUDO is a medicinal plant traditionally used by the indigenous people of Manipur, India, as a room fumigant and a means to ward off evil spirits. The current study was designed to assess the antimicrobial, antioxidant, and neuroprotective properties of I. ternifolius. The dried leaves of I. ternifolius were heat extracted with methanol (ME) and screened for phytochemical constituents. The antimicrobial activity was investigated against pathogenic microbes. In-vitro antioxidant activity was assessed by 2-deoxyribose, 2, 2´-Azinobis-3-ethylbenzo-Thiozoline-6-sulphonate (ABTS), and 1, 1-Diphenyl-2-Picrylhydrazyl (DPPH) assay methods. The endogenous reactive oxygen species (ROS) level on SH-SY5Y cells was detected using 2′,7′-Dichlorofluorescein diacetate (DCF-DA). The neuroprotective activity of ME was studied in rotenone-treated SH-SY5Y cells. ME was observed to have substantial antimicrobial potential against four pathogenic bacterial strains - B. subtilis, Streptococcus, K. pneumoniae and E. aerogenes and also revealed antifungal activity against C. albicans. ME also showed potent free radical quenching activity in chemical and cell-culture-based DCF-DA assays and possesses high phenolic and flavonoid contents. However, ME did not show neuroprotective activity in rotenone-treated SH-SY5Y cells.
Autism Spectrum Disorder Prediction Using Machine Learning and Design Science
Authors: Prasad Rajesh , Musa Farida , Ahmad Hadiza Muhammad , Upadhyay Santosh Kumar , Sharma Birendra Kumar
Published: June 2024

Machine learning, a subset of Artificial Intelligence, has gained much recognition in facilitating disease prediction and the decision-making process in healthcare. One of the most often diagnosed developmental disorders in the world is Autism Spectrum Disorder (ASD). Around the world, it is reported to afflict 75 million people and the number of cases has gradually increased since studies began in the 1960s. The symptoms generally include communication deficits, sensory processing differences, and repetitive actions or behaviors. This research develops a model to detect ASD using Principal Component Analysis and Machine Learning algorithms to classify and predict the risk of ASD among pregnant women. Data was collected from National Hospital in Abuja, Nigeria. According to the results, PCA and Random Forest produced the best accuracy of 98.7%. Bayesian probability was employed to evaluate and verify the reliability of the model. The created model can aid doctors in diagnosing ASD.
SD2S: Multiscale Granger causality analysis based on serial decomposition state space models
Authors: Shuangqin Cheng
Published: June 2024

Granger causality, widely recognized for its ease of use, intuitive interpretability, and applicability to complex multivariate systems, facilitates the inference of causal connections between variables through observational data and elucidates their dynamic interactions. With the advancement of the significant data era, an increasing multiscale characteristic of data is evident, presenting dynamics across multiple temporal scales. Current research in this domain typically relies on vector autoregressive models and wavelet transformations, which are susceptible to noise and dependent on substantial prior knowledge for selecting basis functions. To more accurately interpret and analyze Granger causality at multiple scales, this paper employs state space models and Empirical Mode Decomposition, introducing a novel multiscale Granger causality analysis approach based on serial decomposition state space models (SD2S). Experiments on simulated and real datasets confirm that (1) the integration of Empirical Mode Decomposition with state space models enhances the analysis of multiscale Granger causality; (2) serial decomposition state space models can improve the accuracy of multiscale analysis and effectively reduce computation time; (3) the proposed method successfully identifies dynamic causal relationships that vary with time scales in real-world data.
Lealtades cambiantes. De la defensa de la Corona al apoyo a la Independencia del Perú entre los indígenas de Huamanga, c. 1784-1824
Authors: Quichua Chaico David
Published: June 2024

Este trabajo estudia los factores que permitieron la identificación de los indígenas con la Corona, así como su posterior rechazo a ella. Empleando información de documentos inéditos proponemos que un sector significativo de los indígenas de Huamanga defendió a la administración borbónica porque disfrutaron de privilegios tributarios, la posibilidad de “españolizarse”, continuidad en los cargos de caciques, mayores ingresos económicos, exención de alcabalas, defensa de las tierras comunales, a la vez que proyectos de salud y educación. No obstante, hacia los últimos años de la guerra la imposición de diezmos, los encarcelamientos por el incumplimiento de las mitas de tambo y las alcabalas ilegales y, fundamentalmente, las contribuciones de guerra, motivaron el quiebre de las lealtades. Así, el accionar de los indígenas no fue estático y, por el contrario, la identificación o rechazo a la Corona dependió mucho de las políticas administrativas y los intereses de cada grupo.Este trabajo estudia los factores que permitieron la identificación de los indígenas con la Corona, así como su posterior rechazo a ella. Empleando información de documentos inéditos proponemos que un sector significativo de los indígenas de Huamanga defendió a la administración borbónica porque disfrutaron de privilegios tributarios, la posibilidad de “españolizarse”, continuidad en los cargos de caciques, mayores ingresos económicos, exención de alcabalas, defensa de las tierras comunales, a la vez que proyectos de salud y educación. No obstante, hacia los últimos años de la guerra la imposición de diezmos, los encarcelamientos por el incumplimiento de las mitas de tambo y las alcabalas ilegales y, fundamentalmente, las contribuciones de guerra, motivaron el quiebre de las lealtades. Así, el accionar de los indígenas no fue estático y, por el contrario, la identificación o rechazo a la Corona dependió mucho de las políticas administrativas y los intereses de cada grupo.
Del manejo campesino del fuego al incendio post-campesino en Galicia
Authors: Soto David , Balboa Xesús , Fernández Lourenzo
Published: June 2024

Este trabajo analiza en el largo plazo (siglo XVIII a la actualidad) la evolución del manejo campesino del fuego en Galicia (noreste de España) y el surgimiento de los incendios forestales, como consecuencia del proceso de industrialización de la agricultura y de la ruptura de los agroecosistemas en mosaico propios del manejo campesino. Se estudia la funcionalidad de las estivadas (rozas) en la agricultura orgánica, su integración en el conjunto de manejos campesinos del monte. También se presta atención a los cambios en el manejo de las estivadas durante el proceso de intensificación de la agricultura orgánica entre 1750 y los años treinta del siglo XX. Por último, se estudia la ruptura de las formas de manejo campesino primero por las políticas de la dictadura franquista y después por el impacto de la industrialización de la agricultura. Se analizan los vínculos entre este último proceso y el surgimiento de los incendios como problema recurrente a partir de la década de 1970.
Resultados mais prevalentes de citologia cervical em meio líquido em mulheres no menacme em serviço privado de Fortaleza, Brasil
Authors: Sobreira Silvia Renata Duarte , Cavalcanti Giulia Queiroz , Texeira Mikaelle da Silva , Bezerra Emily Damascena , Lopes Marina Helena da Silva , Eleutério Junior José
Published: June 2024

Introdução: A microbiota vaginal durante o menacme é composta de bactérias importantes para o equilíbrio local. Contudo, desequilíbrios como a vaginose bacteriana são comuns entre mulheres em idade reprodutiva. Assim, é importante analisar a citologia de mulheres na menacme. Objetivo: Identificar achados de citologia cervical em meio líquido de mulheres no período do menacme. Métodos: Estudo transversal, descritivo e quantitativo, com dados da análise citológica em meio líquido (SurePathTM) de amostras do material cervical de 1.227 pacientes no menacme em serviço privado, em Fortaleza, entre janeiro e dezembro de 2022. Variáveis: idade, sintomatologia, contracepção, caracterização de corrimento vaginal (CV) e do colo uterino ao exame e achados colpocitológicos. Resultados: Idades entre 11 e 50 anos, mediana 36. Queixa principal: rotina (79,3%) e corrimento (14,1%), sendo 13,8% associados a outras queixas, como ardor, prurido, dor pélvica e dispareunia. Contracepção: método não informado (32,4%), anticoncepcional combinado oral (19,1%), SIU (14,5%), sendo 63,6% Mirena, nenhum método (10,2%) e condom (9,3%). CV ao exame: branco (33,5%), ausente (31,7%), mucoide (7,0%) e amarelado (5,4%). Exame do colo uterino: normal (82,8%), presença de mácula vermelha periorificial (MVPO) (5,7%), cervicite (3%) e presença de epitélio acetobranco (EAB) (2,2%). Microbiota na citologia: bacilos (43,2%), Gardnerella (14,4%) e Candida (7,5%), sendo 76,3% quadros acentuados. Por fim, 99,9% dos casos foram negativos para malignidade (NML) à citologia e 0,1% células escamosas atípicas de significado indeterminado, mas com origem provavelmente benigna (ASC-US). Conclusão: O corrimento na menacme é, geralmente, uma queixa isolada, mas pode estar associado a outras queixas como ardor, prurido, dor pélvica e dispareunia. Ao exame especular, a maioria tinha colo uterino normal e o CV branco foi encontrado mais frequentemente. Na citologia, encontrou-se microbiota predominante de bacilos e NML.
Teste itinerante: ultrapassando muros, conhecendo cidadãos. Relato de experiencia
Authors: Araújo Túlio César Vieira de , Avelino Edilza Neves , Silva Eloisa Apolinário , Souza Francisca das Chagas Simplício de , Silva Ionete Gomes de Oliveira , Sena Maria Aparecida Germano de , Correia Maria Clara Pinheiro , Oliveira Maria Luiza de , Souza Patrícia Resende Lopes de , Teixeira Rosilene do Nascimento Bernardo
Published: June 2024

Introdução: Segundo a Organização Mundial da Saúde (OMS), todos os dias, mais de 1 milhão de pessoas no mundo contraem uma infecção sexualmente transmissível (IST), em sua maioria assintomáticas, entre elas o HIV, a sífilis e as hepatites B e C. Para tais doenças, um diagnóstico rápido é estratégia de saúde pública. E para auxiliar nessa detecção existem os testes rápidos, porém muitos não têm acesso ou até mesmo não conhecem a existência do teste no Sistema Único de Saúde (SUS). Objetivo: Apresentar o projeto “Teste Itinerante”. Métodos: Idealizado em dezembro de 2019, a partir da inquietação do enfermeiro da Estratégia Saúde da Família (ESF) Parque dos Coqueiros, em Natal, Rio Grande do Norte, o projeto leva a testagem para os equipamentos sociais do bairro respeitando as prerrogativas éticas e possibilitando, assim, conhecer e testar as pessoas que não frequentam a Unidade Básica de Saúde (UBS). O local é acordado previamente, a ação envolve uma equipe multiprofissional e cada usuário é testado para HIV, sífilis e hepatites B e C. Resultados: A primeira ação aconteceu em janeiro de 2020 na feira do bairro, em que 60 cidadãos foram atendidos, 240 testes realizados e cinco positivaram para sífilis, os quais foram acompanhados conforme protocolo. A segunda parada do projeto aconteceu em fevereiro no supermercado do bairro, no qual 55 pessoas foram testadas e três identificadas com sífilis. O projeto foi interrompido em março daquele ano em razão da pandemia de COVID-19. A retomada ocorreu em novembro de 2020 no campo de futebol localizado na frente da UBS. Com um formato reduzido em virtude do contexto ainda pandêmico, a iniciativa retornou testando dez pessoas e tendo um resultado positivo para sífilis. Ao longo de 3 anos, 16 equipamentos sociais foram visitados, 445 usuários testados, 1.780 testes realizados e 25 positivaram para sífilis. Conclusão: O rastreamento das IST sempre estará ligado a uma rede de transmissão. Assim, o número 25 é simbólico. Na prática, incontáveis pessoas foram testadas e tratadas para a sífilis.
A profilaxia pré-exposição na prevenção do HIV: um estudo de scoping review
Authors: Silva Daila Alena Raenck da , Riquinho Deise Lisboa , Barros Mariana Tejada de , Nora Carlise Rigon Dalla
Published: June 2024

Introdução: O início da profilaxia pré-exposição (PrEP) ao Vírus da Imunodeficiência Humana (HIV) como estratégia difundida de prevenção foi em julho de 2012, após a aprovação pelo Food and Drug Administration (FDA). Trata-se da utilização de um único comprimido por dia, composto de dois medicamentos: emtricitabina/tenofovir (FTC/TDF). A adoção da PrEP pautou-se nos resultados de estudos realizados no mundo todo, em populações submetidas a um risco aumentado de infecção pelo HIV. Objetivo: Identificar a PrEP ao HIV na prevenção do HIV nas populações-chave e nos contextos de vulnerabilidade. Métodos: As bases usadas foram: Literatura Latino-americana e do Caribe em Ciências da Saúde (LILACS), Índice Bibliográfico Español en Ciencias de la Salud (IBECS), Base de Dados de Enfermagem (BDENF) e Cumulative Index to Nursing and Allied Health Literature (CINAHL), incluindo National Library of Medicine (PubMed), Scopus, Web of Science e Google Acadêmico. Segue o Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews e o Joanna Briggs Institute. Incluíram-se pesquisas originais, contendo gays, homens que fazem sexo com homens, pessoas transgênero, trabalhadores do sexo e casais sorodiferentes. Resultados: Surgiram 28 artigos, dos quais 11 incluíram homens que fazem sexo com homens; seis apresentaram trabalhadoras do sexo; três, mulheres trans; e dois, casais sorodiferentes. Analisaram-se o conhecimento, a aceitabilidade, as barreiras, as percepções e os contextos de vulnerabilidade. Conclusão: O acesso à profilaxia foi evidenciado, porém há barreiras individuais, sociais e programáticas, destacando-se o desconhecimento, a dificuldade de acesso e os contextos de vulnerabilidade. Há o uso da PrEP em populações-chave, embora existam diferentes obstáculos.
Protagonismo Juvenil – Guarapuava, Paraná
Authors: Camargo Angela Maria de , Silva Hiagor , Fortini Priscila Ferreira , Borecki Marlene Terezinha , Souza Claudia Bahls de , Borba Kátia , Andrade Felipe Santos , Pereira Maria Eduarda Padilha , Pereira Jefferson Luiz Skuareki , Machado Viviane
Published: June 2024

O projeto Protagonismo Juvenil prevê a atuação de jovens universitários no espaço das Instituições de Ensino Superior, como sujeitos conscientes de sua condição de personagens principais da própria história, que depende das relações estabelecidas com as inúmeras histórias de sua coletividade. Protagonistas juvenis são capazes de influenciar outros jovens a promoverem saúde e estilos de vida saudáveis, reduzindo vulnerabilidades às infecções sexualmente transmissíveis (IST)/AIDS, tuberculose (TB) e hepatites virais. A região Sul do Brasil, especificamente o Paraná, tem apresentado indicadores epidemiológicos que apontam crescimento dos indicadores da infecção pelo HIV e pelos vírus das hepatite B e C, TB, além de altos índices de sífilis, principalmente no seguimento jovem. Os objetivos são capacitar jovens protagonistas para influenciar outros jovens a promover saúde e estilo de vida saudável; reduzir a vulnerabilidade das hepatites B e C, das IST, da TB e da AIDS; e utilizar o protagonismo como estratégia de promoção, prevenção, educação e comunicação em saúde. Já foram capacitados 130 jovens e seis professores universitários. As ações correm dentro do próprio campus, nas Unidades Básicas de Saúde (UBS), e na comunidade com ações extramuros e população vulnerável (presídios, profissionais do sexo, ensino médio, CAPS, entre outros). Os jovens são capacitados em parceria com a 5ª regional, são certificados como testadores em testagem rápida, contribuindo no diferencial da sua formação como futuro profissional de saúde. O projeto tem ações nos três eixos (ensino, pesquisa e extensão) e está aprovado como projeto municipal de saúde. Ações desenvolvidas: campanha do dezembro vermelho — 232 testes realizados; PEG (privados de liberdade) — 416 testes; Carnaval Seguro — 244 testes; CAPS — 80 testes; Hospital Virmod — 68 testes; Campus UNICENTRO — 164 testes. Em 2023 estão previstas ações em parceria com o Saúde e Preveção nas Escolas (SPE). Podemos realizar prevenção efetiva, uma vez que os autores dialogam entre si. Esse projeto corrobora para o desenvolvimento de novas ações.
Validação do processo de liofilização de amostras de plasma para envio de rodadas do Programa Nacional de Avaliação Externa da Qualidade para a rede de carga viral convencional e rápida
Authors: Rudolf Renata Cristina Messores , Leismann Adriane Wendling , Martins Damaris Miriã , Barazzetti Fernando Hartmann , Schörner Marcos André , Medeiros Taiane Freitas , Ramos Martin Benitez , Penha Larissa Cristine de Carvalho , Bazzo Maria Luiza
Published: June 2024

Introdução: O Programa Nacional de Avaliação Externa da Qualidade (AEQ) é uma parceria entre o Laboratório de Biologia Molecular, Microbiologia e Sorologia da Universidade Federal de Santa Catarina (UFSC) e o Departamento de HIV/AIDS, Tuberculose, Hepatites Virais e Infecções Sexualmente Transmissíveis (DATHI/SVSA/MS). Esse programa integra a AEQ para carga viral convencional e rápida. Até 2022, os painéis eram produzidos com plasma líquido, enviados por transportadora especializada e com prazo de entrega de no máximo 48 horas. Esse tipo de transporte, apesar de rápido, apresenta alto custo. Objetivo: Validar o processo de liofilização das amostras de plasma para envio das rodadas AEQ para a rede de laboratórios de carga viral convencional e rápida para possibilitar o envio por Correios (sem cadeia de frios) e com estimativa de redução no custo do transporte em até 80%. Métodos: Foram produzidos painéis para HIV, vírus da hepatite C (HCV) e vírus da hepatite B (HBV) com cargas virais média e baixa. As amostras liofilizadas foram mantidas em diferentes temperaturas (21–25°C, 2–8°C, 35°C e 45°C), hidratadas e testadas nos dias 7, 14, 21 e 35 após a liofilização. Adicionalmente, testou-se a estabilidade após a hidratação nos tempos de 20 minutos, 12 horas, 24 horas, 36 horas e 48 horas. Resultados: O processo de liofilização gera uma redução na carga viral em comparação ao resultado obtido no plasma líquido. As amostras liofilizadas apresentaram boa estabilidade entre 14 e 21 dias em temperatura ambiente, sendo prejudicada em temperaturas altas, principalmente se mantidas a 45°C. Também apresentam boa estabilidade hidratadas por até 24 horas, sendo ideal fazer as quantificações nas primeiras seis horas após a hidratação. Conclusão: O processo de liofilização foi validado. Em 2022 foi enviada uma rodada piloto para cinco instituições da rede convencional e cinco da rede rápida, corroborando os resultados obtidos na validação laboratorial. Em 2023, foi enviada uma rodada completa para toda a rede de carga viral rápida.
Validação de corante vermelho em substituição ao corante azul de tripan em painéis DTS do Programa Nacional de Avaliação Externa da Qualidade dos testes rápidos
Authors: Rudolf Renata Cristina Messores , Kerber Guilherme , Bazzo Maria Luiza
Published: June 2024

Introdução: O Programa Nacional de Avaliação Externa da Qualidade (AEQ) é uma parceria entre o Laboratório de Biologia Molecular, Microbiologia e Sorologia da Universidade Federal de Santa Catarina (UFSC) e o Departamento de HIV/AIDS, Tuberculose, Hepatites Virais e Infecções Sexualmente Transmissíveis (DATHI/SVSA/MS). Em 2011, a AEQ para testes rápidos (TR) passou a integrar o Programa Nacional e atualmente já ocorreram 26 rodadas de avaliação. A metodologia para o envio das amostras é DTS (amostras secas em tubo), que permite transporte sem refrigeração e baixo risco biológico. Até 2021, a secagem das amostras de soro ou plasma era feita com a utilização do corante azul de tripan. A coloração azul dificultava a compreensão dos participantes do programa de que as amostras deveriam ser tratadas como sangue total. Objetivo: Validar um corante vermelho para mimetizar amostras de sangue total. Métodos: Realizou-se a triagem com sete corantes. Com o corante que apresentou coloração mais próxima ao sangue total, foram produzidos painéis para sífilis, HIV e vírus da hepatite C (HCV). Os painéis foram armazenados em temperatura de 2–8°C, 21–25°C, 37°C e 42°C e em alta e baixa umidade, e testados com os TR para cada agravo em 1, 7, 14, 21, 28, 30, 35 e 40 dias pós-preparação. Resultados: O corante vermelho alimentício em pó apresentou coloração similar ao sangue total após secagem, coloração vermelho-claro após a hidratação, boa solubilidade e não ocasionou manchas na membrana dos TR. Além disso, o corante vermelho se mostrou superior ou equivalente ao azul na reatividade observada nos TR nas diversas condições de temperatura e umidade. Conclusão: A partir da rodada 22AEQ-TR (2021) o corante azul foi substituído pelo corante vermelho, e isso reduziu drasticamente as dúvidas dos participantes com relação à amostra biológica, pois passaram a identificar as amostras vermelhas como sangue total.
Some measures to urgently combat the clinical manifestations of allergies of the immediate type in therapeutic dentistry
Authors: Burlacu Valeriu , Cartaleanu Angela , Tintiuc Elena
Published: June 2024

The given information demonstrates the effectiveness of urgent application of measures to combat allergic reactions of immediate type in therapeutic dentistry. The actuality of the subject In the clinical activity of the dentist, as in other branches of medicine, emergency situations may arise, necessary to be quickly diagnosed, providing the patient with timely and effective medical help. University professor Stenli Malomed (2009, Los Angeles, USA) subjected to a deep analysis the frequency of emergency states arising in the work of private dentistry (4000 doctors) during ten years of clinical activity. The results presented about 30000 extreme situations from which they were assessed: fainting in 15407 cases; mild allergic reactions in 2583 cases, and anaphylactic type in 304 cases. As well as in the successes of the world performing resuscitation, the morbidity from anaphylactic shock (Rabinovich S. A., 2005) reached 60 to 100 of the clinical cases of the pathology. Purpose of the work Estimation of clinical effectiveness of emergency antiallergic measures granted in case of immediate type reactions occurring in the work of therapeutic dentists.
The development of toxic osteomyelitis in drug using patients
Authors: Stefanet Veronica , Rusu-Radzichevici Natalia
Published: June 2024

Toxic osteomyelitis of the jaws, also known as osteonecrosis of the jaws, is a separate entity of odontogenic osteomyelitis, appearing predominantly post–extraction, without clear delimitation and without a tendency to heal in the long term, and appears on the background of drug consumption which contain red phosphorus, iodine and ephedrine. These changes appear as a result of the action of some physical or chemical factors, to which the infection is added.
Methods of distalization . Literature rewiew
Authors: Calfa Sabina , Trifan Valentina , Leşco Tatiana , Pretuleac Mariana
Published: June 2024

As orthodontics has evolved, the focus of practice has shifted from extractions to alternative methods of dental alignment, taking into account facial aesthetics. The distalization of the maxillary molars, in use for over a century, has emerged as an effective solution for a variety of orthodontic challenges, including dental crowding and Class II malocclusion. Distalization methods vary based on the characteristics of the case and the biomechanics of the device, ranging from fixed to removable devices and from intraoral to extraoral. Although the Headgear, Herbst, Distal Jet, and Pendulum are among the most commonly used techniques, all require careful patient selection. Moreover, the recent use of skeletal anchorage via mini-implants extends distalization possibilities, providing solutions for complex cases. Thus, it’s essential for the clinician to evaluate and choose the most suitable technique for each patient.
Factors Influencing Employee Engagement and Innovative Work Behavior -- A Case Study of Hi-Tech Company in China
Authors: Yandong Li , Wareewanich Thitinant
Published: June 2024

This study examines the factors influencing employee engagement and innovative work behavior in a case study of a Hi-Tech Company in China. Specifically, the relationships between Career Growth (CGH), Recognition (REC), Job Involvement (JIT), Job Responsibility (JRY), Employee Engagement (EET), and Innovative Work Behavior (IWB) among employees are investigated. The research objectives include identifying the relationships between these factors and exploring the mediating effect of employee engagement on the relationship between Career Growth, Recognition, Job Involvement, Job Responsibility, and Innovative Work Behavior. Data was collected through surveys conducted at the Hi-Tech Company's headquarters in Shenzhen, China. Quantitative research methods were employed to analyze the data, including structural equation modeling and mediation analysis. The findings suggest significant relationships between Career Growth, Recognition, Job Involvement, Job Responsibility, Employee Engagement, and Innovative Work Behavior. Additionally, employee engagement was found to mediate the relationships between Career Growth, Recognition, Job Involvement, Job Responsibility, and Innovative Work Behavior. These results provide valuable insights for understanding and promoting employee engagement and innovative work behavior within Hi-Tech companies in China.
Optimization of Selective Laser Melting Process Parameters for Enhanced Mechanical Properties and Friction Behavior of AlFeSi10Mg Alloy Components
Authors: Kalluru Madhurima , Devi Dr.K.Devaki
Published: June 2024

This research investigates wear characteristics of an AlFeSi10Mg alloy produced through selective laser melting (SLM), while introducing a layer-by-layer additive process simulation to streamline the SLM printing process, thereby saving time, cost, and material. AM simulation results demonstrate reduced displacement and temperature during SLM printing. The study emphasizes the critical role of build orientation in determining the quality and performance of AM parts. Employing an L16 orthogonal array of Taguchi design experiments, a model is developed for wear characterization. Optimal process parameters are identified for achieving low wear rate, high density, and high hardness. At the optimal condition (T5), wear measurements include a depth of 94 micrometers, a length change of 0.06%, a volume of 1.25 mm3, a velocity of 1674.46 mm/s, a wear rate of 4.97×10-8 mm2/N, a coefficient of 0.04 mm2/N, and a frictional force of 14.1 N. Laser energy density is computed as 150 J/mm3 based on the achieved optimal parameters.
Teknik Random Forest untuk Meningkatan Akurasi Data Tidak Seimbang
Authors: Nugroho Arie , Harini Dwi
Published: June 2024

Data tidak seimbang terjadi karena jumlah data pada tiap kelas berbeda jauh dimana akan mempengaruhi hasil prediksi. Dalam penelitian ini menggunakan dataset prediksi diabetes, yang mengandung data yang tidak seimbang. Hasil prediksi ditunjukkan dengan nilai akurasi dan presisi. Tujuan penelitian ini adalah meningkatkan nilai akurasi dan presisi pada data yang tidak seimbang. Metode yang digunakan dalam penelitian ini adalah penentuan sampling dan pembelajaran ensemble. Penentuan sampling yang digunakan adalah dengan cara mengalikan data pada kelas minoritas atau oversampling. Teknik Oversampling yang digunakan adalah Synthetic Minority Oversampling Technique (SMOTE). Pembelajaran ensemble yang digunakan adalah algoritma random forest. Kombinasi algoritma SMOTE dan random forest dapat meningkatkan akurasi dan menyeimbangkan nilai presisi pada setiap kelas. Hasil penelitian ini adalah Kombinasi tersebut menghasilkan nilai akurasi sebesar 97,5% dan nilai presisi pada kelas non pasien sebesar 97% sedangkan nilai presisi pada kelas pasien sebesar 98%.
Psychic illness in men in Northeastern Brazil: mental health in debate
Authors: Bezerra Edilane Nunes Régis
Published: June 2024

Psychic illness, with emphasis on Common Mental Disorders (CMD), is one of the major problems faced today, compromising the health of populations and representing a high burden on public health. However, the incipience of studies focusing on men's health needs within the scope of primary care is notable. This study aims to analyze aspects of vulnerability to common mental disorders in men living in the rural context of municipalities in Paraíba, associated with socioeconomic factors, lifestyles, search for care and mental health. A set of instruments was applied: SRQ-20 (screening of non-psychotic mental disorders); sociodemographic questionnaire and semi-structured interviews, based on the scene method, with the aim of understanding the meanings that people attribute to the different dimensions of their daily life and, thus, decoding the dimensions of vulnerability, as an analysis method we used thematic analysis. It is evident that a large part of the non-adherence to comprehensive care measures, on the part of men, arises from cultural aspects. They feel strong and invulnerable.
IMPACT OF IN-SERVICE TRAINING ON PEOPLE-FOCUSED AND DEMOCRATIC LEADERSHIP SKILLS AMONG EDUCATIONAL MANAGERS OF PUNJAB
Authors: Abbas Muhammad , Sarwar Muhammad , Rehman Raza-Ur-
Published: June 2024

This quantitative study examined the impact of in-service training offered by Quaid-e-Azam Academy for Educational Development (QAED) on the people-focused and democratic leadership skills of educational managers in Punjab, Pakistan. Random sample of 359 educational managers from the Punjab province participated in study. Data were collected using adopted questionnaires based on indicators used during QAED's in-service training sessions, administered through Google form with a five-point Likert scale. The results revealed that majority of participants perceived the in-service training as effective in enhancing people-focused & democratic leadership skills. The study highlights the importance of well-designed, targeted, and collaborative training programs in developing essential leadership skills, fostering collaboration and networking, realizing ongoing support systems & regularly assessing the effectiveness of training initiatives. The findings contribute to the growing body of research emphasizing the significance of professional development for educational leaders & implications for policy and practice in the education sector, as well as for leadership development in other industries.
The Knowledge of Hepatitis B Infection And Practice Towards Its Prevention Among Pregnant Women
Authors: Kanikwu Phoebe Nwamaka , Onukwu Patricia Udo , Olaniyan Mathew Folaranmi , Muhibi Musa Abidemi
Published: June 2024

Infection with Hepatitis B remains a health challenge across the globe. This descriptive survey focused on the knowledge of hepatitis B infection (HBI) and prevention practices of pregnant women. Thus, this study assessed knowledge of HBI, HBI prevention practices, factors affecting the practice of HBI prevention among pregnant women, the association between the socio-demographic characteristics cum knowledge of HBI, as well as the relationship between the knowledge of HBI and the prevention practices. Balloting with replacement was employed in selecting 267 pregnant women attending an antenatal clinic in Delta State, Nigeria. The instrument for data collection was a Questionnaire developed by the researchers. The reliability of the instrument was conducted using Cronbach alpha which yielded coefficient of 0.738. Data collected were analyzed using frequencies, percentages, mean, Kruskal Walis test and Chi-Square statistic test. Majority of the study respondents (53.8%) had low level of knowledge about HBI but 60% had good level of prevention practice. 36.7% of the pregnant women believed that they had a low-risk status for HBI, 43.4% that prayer was more effective than vaccine and 60.7% that herbal medicine was available to prevent HBI. Significant association did not exist between pregnant women’s socio-demographic characteristics and their knowledge of HBI (k=2.92, p-value=0.10). Significant relationship existed between knowledge of HBI and the prevention practices of pregnant women (X2=36.71; p-value=0.001). Findings showed that the pregnant women had a low knowledge level for hepatitis B virus but a good level of prevention practice possibly due to high level of provider-initiated preventive services. Nurses should organize more detailed health education sessions on hepatitis B infection to pregnant women and keep up with their role of performing provider-initiated preventive services.
Resilience and Quality of Life on Type 2 Diabetes Mellitus Patients with Chronic Complications
Authors: Nur Widayati  , Izdihar Javier Wardika  , Akhmad Zainur Ridla
Published: June 2024

The emergence of complications in patients with type 2 DM significantly impacts the quality of life. Resilience as part of self-coping may be connected with the quality of life and the severity of the complications. This study analyzed the correlation between resilience and quality of life in type 2 DM patients with chronic complications. The method was an observational study with a cross-sectional approach. Thirty-five respondents were recruited in this study using a consecutive sampling technique. Data were collected using Connor Davidson Resilience Scale 25 (CD-RISC 25) and Diabetes Quality of Life (DQOL) questionnaires and analyzed by Pearson Product Moment (p <0.05). The result showed that the mean value of resilience was 63.06 (±12.47), while the average value of quality of life was 72.46 (±11.78). A strong positive correlation existed between resilience and quality of life (p-value = 0.000; r = 0.782). Increased resilience score equals increased quality of life of type 2 DM patients with chronic complications. Providing interventions to increase resilience is essential to optimize the quality of life in type 2 DM patients with chronic complications.
Understanding Parenteral Behavior Changes Through Supplementary Feeding: A Small Group Discussion
Authors: Lina Mahayaty  , Citra Darmawan Taufan , Nirmala Santiasari Retty , Wahyu Prasetyo Niko
Published: June 2024

Supplementary Feeding (SF) is a program providing additional food to groups in need of nutritional supplements, especially malnourished children. For malnourished children, food provision is one way to prevent growth and developmental problems. This study aims to evaluate the effect of health education on supplementary feeding using the SGD method on parental behavior. This research method employs a pre-experimental design with a One Group Pre-Post Test approach involving 32 parent respondents with children exhibiting poor or inadequate nutrition status at the Integrated Health Post for Toddlers “Posyandu Balita”. This research use Parrent Behaviour Questionnaire (PBQ). The PBQ is a 38 item self-report instrument which assesses the importance of specific parenting behaviors, this questionnaire showing a valid and reliable (Cronbach’s α > 0.7) structure. The Wilcoxon Test yielded a result of p = 0.000021 with a significance level of p < 0.05, indicating an impact on parental behavior in providing SF at the Integrated Health Post for Toddlers. Health education through the SGD method enhances parental understanding of the importance of SF consumption for toddlers. Through the SDG method, parents can share experiences and increase awareness of the importance of providing supplementary feeding, particularly to toddlers experiencing malnutrition. It is hoped that this research will encourage parents to be more proactive in meeting the nutritional needs of their children.
Kidney Transplantation in Elderly Recipients: Five-Year Experience
Authors: Paulo Núria , Fernandes Vítor , Cerqueira Ana , Bustorff Manuela , Pinho Ana , Sampaio Susana , Pestana Manuel
Published: June 2024

Objectives: The prevalence of end-stage renal disease is rising among older adults worldwide. Despite kidney transplantation being considered the best renal replacement therapy, it presents unique challenges in elderly patients. This study aims to describe deceased donor kidney transplantation in our center, analyze outcomes namely delayed graft function (DGF), acute rejection, bacterial infections, and death-censored allograft loss in patients aged 65 years or older, and compare graft and patient survival with recipients younger than 65 years old. Methods: A single-center retrospective cohort study of kidney transplantation from a deceased donor between 2016 and 2020 was conducted. Data on donor, recipient, and transplant characteristics were collected, and outcomes after transplantation were analyzed. Univariate Cox regression was used to compare patient and death-censored allograft survival between older and younger patients. Results: Of the 294 deceased-donor transplants performed, 48 were allocated to recipients aged 65 years or older. These patients had a significantly higher prevalence of extended criteria donors (ECD) when compared to younger recipients (p < 0.001). The mean recipient age in the elderly group was 68 ± 2 years, with a median follow-up of 29 months (interquartile range [IQR] 18-49). During the 1st year, five (10.4%) patients were diagnosed with biopsy-proven acute rejection and 24 (50%) with bacterial infections. DGF was observed in 27 (56.3%) patients and was associated with a higher proportion of high-risk donors (ECD and uncontrolled circulatory death donors with normothermic regional perfusion) (p = 0.034), longer cold ischemic times (p = 0.031), and hospitalization duration (p < 0.001). Death-censored allograft survival at 1, 3, and 5 years was 89.1, 89.1, and 84.6%, respectively, which was not statistically different from the group of younger recipients (p = 0.56). Throughout follow-up, five patients died, three (60%) of whom had a functioning allograft. Patient survival at 1, 3, and 5 years was 100, 97.6, and 79.2%, respectively, again showing no notable differences compared to younger recipients (p = 0.12). Conclusion: Even though an individualized approach and careful pre-transplant evaluation are key for the success of kidney transplantation in the elderly population, our 1, 3, and 5-year death-censored allograft and patient survival in older patients were similar to younger recipients.
Validation of Musculoskeletal Tissue Capture from a Living Donor: Experience from a Multi-tissue Bank
Authors: Filho Luiz Henrique de Freitas , Neves Cristina de Carvalho Silva , Corsi Carlos Alexandre Curylofo , Cardoso Evelyn Machado , Silva Nilcilene Pinheiro , Campos Gustavo Constantino de
Published: June 2024

Introduction: The harvesting of musculoskeletal tissues is essential to ensure the supply of biological products of human origin with safety and clinical efficacy. The harvesting stage must undergo a validation process to guarantee the quality of the tissues.Objectives: This article describes the experience of a public human multi-tissue bank (HMTB) in validating the harvesting of musculoskeletal tissue (femoral head) from a living donor. Methods: This involves evaluating and adapting a harvesting protocol to promote excellence in the quality of tissues distributed for therapeutic and research purposes. To this end, a technical visit was carried out at another tissue bank, and meetings were held with the orthopedic service team to present and discuss the process flow. Donor screening was done by applying forms evaluating the selection and exclusion criteria. After acceptance, through the consent form, the donor’s serological tests were requested and collected. The harvesting kit, control of the temperature thermal transport box, and collecting microbiological material from the piece at the time of removal were validated. The validated harvested tissue underwent macroscopic, radiological, and microbiological evaluations to consider the process valid. The forms and other documents in the medical record were audited by the institution’s health quality and safety center. Process mapping was also carried out, targeting risks and opportunities for improvement. Results: The harvesting protocol was validated as foreseen in the action plan. The harvesting technique was performed sterilely in the operating room. Microbiological and serological analyses showed negative results, and the tissue was considered macroscopically viable. After the audit, the documentation was deemed adequate to comply with current legislation (Resolução da Diretoria Colegiada – RDC Nº 707, of July 1, 2022), and the mapping of processes guaranteed the security of harvesting and provided opportunities for improvement. Conclusion: A protocol for capturing musculoskeletal tissues in the reference service is presented, with the validation process being replicable through a fundamental tool to ensure harmlessness and safety in tissue harvesting.
Interactive storytelling elements in R. L. Stine’s “Give Yourself Goosebumps #2: Tick Tock, You’re Dead!”
Authors: Binambuni Yohana Aurilia , Kurniadi Didit , Heriyanto Eko
Published: June 2024

This study explores the captivating world of interactive storytelling, focusing on how it brings horror narratives to life through the lens of R.L. Stine’s “Give Yourself Goosebumps #2: Tick Tock, You’re Dead!”. With storytelling evolving in the digital age, this study aims to unravel the elements behind what keeps readers hooked. This study uses qualitative descriptive method, specifically using literary analysis approach, dissecting the novel to uncover hidden gems and patterns. This study shows that interactive storytelling within horror narrative is not just about scaring the readers—it is a powerful tool that entertains, challenges, and inspires readers and authors alike. This study touches on interactive storytelling elements such as decision points, reader agency, consequences of choices, multiple storylines, and replay-ability, these techniques add layers to the horror narrative experienced by the readers.