bluuebunny/crossref_metadata_2025 huggingface dataset:
Disciplina de inspeção sanitária: alteração de cronograma e avaliação de graduandos em medicina veterinária
Authors: Galvão Victor Chiaroni , Balian Simone De Carvalho
Published: August 2020

A disciplina de Inspeção Sanitária dos Produtos de Origem Animal (ISPOA) da Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo passou por várias transformações ao longo do tempo devido aos avanços tecnológicos e científicos. O cronograma da disciplina de ISPOA foi reformulado em blocos de conteúdos estreitamente correlatos ou em blocos em que os assuntos não se relacionavam. Houve a aplicação de uma nova metodologia de avaliação de aprendizagem que ocorreu ao fim de cada bloco de conteúdo através de prova teste múltipla escolha (PTME). A amostra deste estudo foi formada por 168 alunos do 9º semestre de medicina veterinária entre os anos 2017 e 2018. Foram utilizadas análise estatística descritiva e multivariada (teste t) dos dados. Os resultados demonstraram que houve aumento das notas entre os anos de 2017 e 2018. O resultado do teste t foi de t = 1,12-24, ou seja, p < 0,05 evidenciando que ocorreu diferença estatística entre as médias das notas entre os alunos de 2017 e 2018. Conclui-se que a organização da disciplina de ISPOA e a aplicação das PTME após os blocos de conteúdo aumentaram o desempenho dos alunos.
Articulação ensino-extensão: experiência na educação de jovens e adultos nas escolas da rede municipal de Belo Horizonte
Authors: Castro Letícia Bernardes de , Fernandes Lucas Araújo
Published: August 2020

Introdução: O ensino universitário vem preparando o acadêmico com o conteúdo teórico, mas também com práticas que buscam aumentar o contato do estudante com a comunidade. O presente relato apresenta as atividades realizadas pelo projeto de extensão RessuscitAÇÃO, realizado por acadêmicos da Faculdade de Ciências Médicas de Minas Gerais. Justificativa: Os episódios de parada cardiorrespiratória são muito prevalentes no Brasil e no mundo, sendo necessário capacitar a população leiga sobre técnicas de ressuscitação cardiopulmonar. No caso dos professores do EJA, essa ação é relevante, uma vez que parte dos alunos apresenta idade elevada. Objetivos: Discutir as atividades do projeto RessuscitAÇÃO e seus resultados, assim como seu impacto e os benefícios de sua implementação. Materiais e métodos: O projeto realizado capacitou professores da rede de Educação de Jovens e Adultos (EJA) de escolas municipais de Belo Horizonte sobre as técnicas de ressuscitação cardiopulmonar. Discussão: Os projetos de extensão são recursos que propiciam uma articulação entre os conteúdos aprendidos na sala de aula com a sua extensão prática na comunidade. Durante a execução desse projeto, foram alcançados 26 professores do EJA, os quais foram capacitados com o protocolo de ressuscitação cardiopulmonar destinado a leigos. Conclusão: O projeto RessuscitAÇÃO atingiu seus objetivos, e a articulação entre ensino e extensão foi percebida pelos acadêmicos participantes, que tiveram a função de ensinar e qualificar corretamente os professores.
Processing of Different Temporal Scales in the Human Brain
Authors: Monsa Rotem , Peer Michael , Arzy Shahar
Published: August 2020

While recalling life events, we reexperience events of different durations, ranging across varying temporal scales, from several minutes to years. However, the brain mechanisms underlying temporal cognition are usually investigated only in small-scale periods—milliseconds to minutes. Are the same neurocognitive systems used to organize memory at different temporal scales? Here, we asked participants to compare temporal distances (time elapsed) to personal events at four different temporal scales (hour, day, week, and month) under fMRI. Cortical activity showed temporal scale sensitivity at the medial and lateral parts of the parietal lobe, bilaterally. Activity at the medial parietal cortex also showed a gradual progression from large- to small-scale processing, along a posterior–anterior axis. Interestingly, no sensitivity was found along the hippocampal long axis. In the medial scale-sensitive region, most of the voxels were preferentially active for the larger scale (month), and in the lateral region, scale selectivity was higher for the smallest scale (hour). These results demonstrate how scale-selective activity characterizes autobiographical memory processing and may provide a basis for understanding how the human brain processes and integrates experiences across timescales in a hierarchical manner.
Stepping Inside the Classification Cube: An Intimate Interaction with an AI System
Authors: Meshi Avital , Forbes Angus G.
Published: August 2020

The Classification Cube art installation invites participants to become familiar with a machine-learning classification system. Inside a private space within the gallery, participants’ bodies are subjected to a classification process that detects their faces and estimates their age, gender, emotion and actions. Participants are also able to see how their own classification compares with how the installation classifies a series of animated figures. Rapidly changing results encourage participants to actively perform their behavior to the system and alter the way it “sees” them. The entanglement with the system raises awareness regarding the effectiveness of machine interpretation.
Active disturbance rejection attitude control for the dove flapping wing micro air vehicle in intermittent flapping and gliding flight
Authors: Liang Shaoran , Song Bifeng , Xuan Jianlin , Li Yubin
Published: August 2020

This paper proposes an attitude control scheme for the Dove flapping wing micro air vehicle in intermittent flapping and gliding flight. The Dove flapping wing micro air vehicle adopts intermittent flapping and gliding flight to make the wing movements more natural; this strategy also has the potential to reduce energy consumption. To implement this specific flight mode, this paper proposes a closed-loop active disturbance rejection control strategy to stabilize the attitude during the processes of flapping flight, transition and gliding flight. The active disturbance rejection control controller is composed of three parts: a tracking differentiator, a linear extended state observer and a nonlinear state error feedback controller. The tracking differentiator estimates the given target signal and the differential signal in real time. The extended state observer estimates the system states and system nonlinearity. Moreover, the bandwidth parameterization method is applied to determine the observer gains. The stability of the closed-loop system is verified using Lyapunov’s theorem. Several outdoor flight experiments have been conducted to verify the effectiveness of the proposed control method, and the results show that the proposed method can guarantee the stability of intermittent flapping and gliding flight.
In childhood mature B-NHL with CNS disease, patients with blasts in cerebrospinal fluid are at higher risk of failure
Authors: Simonin Mathieu , Auperin Anne , Bertrand Yves , Aladjidi Nathalie , Baruchel André , Contet Audrey , Coze Carole , Gandemer Virginie , Haouy Stephanie , Leblanc Thierry , Leverger Guy , Michon Jean , Patte Catherine , Minard-Colin Veronique
Published: August 2020

To identify the factors influencing outcome in childhood mature B-cell non-Hodgkin lymphoma and acute leukemia (B-NHL/AL) with central nervous system (CNS) disease (CNS+), we analyzed patients <18 years with newly diagnosed B-NHL/AL registered in 3 Lymphomes Malins B studies in France between 1989 to 2011. CNS+ was diagnosed on fulfillment of ≥1 of the following criteria: any L3 cerebrospinal fluid (CSF) blasts (CSF+), cranial nerve palsy, isolated intracerebral mass but also clinical spinal cord compression, and cranial or spinal parameningeal extension. Two hundred seventeen out of 1690 patients (12.8%) were CNS+. CNS+ was significantly associated with male gender, head/neck locations, Burkitt histology, high initial lactate dehydrogenase (LDH) level, and bone marrow involvement. CSF+ was the most frequent pattern of CNS+ (45%). For the 217 CNS+ patients, the 5-year event-free survival (EFS) and overall survival rates (95% confidence interval) were 81.5% (75.8% to 86.1%) and 83.9% (78.4% to 88.2%), respectively. In multivariate analysis, among CNS+ patients, low EFS was associated with CSF+, high initial LDH level, and poor response to cyclophosphamide, oncovin (vincristine), prednisone prephase. These findings have been considered for patient’s stratification in the international randomized phase 3 trial Inter-B-NHL-ritux 2010 for children and adolescents with high-risk B-NHL/AL with CNS+ CSF+ patients only receiving intensified chemotherapy.
End-of-life care quality outcomes among Medicare beneficiaries with hematologic malignancies
Authors: Egan Pamela C. , LeBlanc Thomas W. , Olszewski Adam J.
Published: August 2020

Patients with hematologic malignancies are thought to receive more aggressive end-of-life (EOL) care and have suboptimal hospice use compared with patients with solid tumors, but descriptions of EOL outcomes from comprehensive cohorts have been lacking. We used the population-based Surveillance, Epidemiology, and End Results–Medicare dataset to describe hospice use and indicators of aggressive EOL care among Medicare beneficiaries who died of hematologic malignancies in 2008-2015. Overall, 56.5% of decedents used hospice services for median 9 days (interquartile range, 3-27), 33.0% died in an acute hospital setting, 36.8% had an intensive care unit (ICU) admission in the last 30 days of life, and 13.3% received chemotherapy within the last 14 days of life. Hospice use was associated with 96% lower probability of inpatient death (adjusted risk ratio [aRR], 0.038; 95% confidence interval [CI], 0.035-0.042), 44% lower probability of an ICU stay in the last 30 days of life (aRR, 0.56; 95% CI, 0.54-0.57), and 62% decrease in chemotherapy use in the last 14 days of life (aRR, 0.38; 95% CI, 0.35-0.41). Hospice enrollees spent on average 41% fewer days as inpatient during the last month of life (adjusted means ratio, 0.59; 95% CI, 0.57-0.60) and had 38% lower mean Medicare spending in the last month of life (adjusted means ratio, 0.62; 95% CI, 0.61-0.64). These associations were consistent across histologic subgroups. In conclusion, EOL care quality outcomes and hospice enrollment were suboptimal among older decedents with hematologic cancers, but hospice use was associated with a consistent decrease in aggressive care at EOL.
Tanshinone IIA regulates human AML cell proliferation, cell cycle, and apoptosis through miR-497-5p/AKT3 axis
Authors: Nie Zi-Yuan , Zhao Ming-Hui , Cheng Bao-Qian , Pan Rong-Fang , Wang Tian-Rui , Qin Yan , Zhang Xue-Jun
Published: August 2020

Background

The roots of Salvia miltiorrhiza are used in traditional Chinese medicine (TCM) and have high medicinal value. Tanshinone IIA (Tan IIA) is the active ingredient of Salvia miltiorrhiza which can inhibit the growth of acute leukemia cell lines in vitro, although the mechanism remains unclear.

Methods

CCK-8 assays and BrdU stain were used to evaluate cell proliferation ability. Western blot analysis was used to detect protein expression. miR-497-5p expression level was detected by using qRT-PCR, and Annexin V-FITC/propidium iodide (PI) was used to detect cell apoptosis.

Results

Here we reported that Tan IIA could inhibit cell proliferation, induce cell cycle arrest, and promote cell apoptosis in acute myeloid leukemia (AML) cells. Thus, Tan IIA had the anti-cancer activity in AML cell lines, which was likely mediated by up-regulation of miR-497-5p expression. Our data further showed that in AML cells, the same effects were observed with overexpression of miR-497-5p by a miR-497-5p mimic. We demonstrated that Tan IIA could inhibit the expression of AKT3 by up-regulating the expression of miR-497-5p. We subsequently identified that AKT3 was the direct target of miR-497-5p, and that treatment with Tan IIA obviously reversed the effect of treatment with an miR-497-5p inhibitor under harsh conditions. In turn, PCNA expression was increased and cleaved Caspase-3 was suppressed, which contributed to the growth of AML cells.

Conclusions

Our results showed that Tan IIA could inhibit cell proliferation in AML cells through miR-497-5p-mediated AKT3 downregulation pathway.
Synergy between hemagglutinin 2 (HA2) subunit of influenza fusogenic membrane glycoprotein and oncolytic Newcastle disease virus suppressed tumor growth and further enhanced by Immune checkpoint PD-1 blockade
Authors: Miri Seyed Mohammad , Ebrahimzadeh Mir Saeed , Abdolalipour Elahe , Yazdi Mahsa , Hosseini Ravandi Hassan , Ghaemi Amir
Published: August 2020

Background

Newcastle disease virus (NDV) has shown noticeable oncolytic properties, especially against cervical cancer. However, in order to improve the spread rate and oncotoxicity of the virus, employment of other therapeutic reagents would be helpful. It has been shown that some viral fusogenic membrane glycoproteins (FMGs) could facilitate viral propagation and increase the infection rate of tumor cells by oncolytic viruses. Additionally, immune checkpoint blockade has widely been investigated for its anti-tumor effects against several types of cancers. Here, we investigated for the first time whether the incorporation of influenza hemagglutinin-2 (HA2) FMG could improve the oncolytic characteristics of NDV against cervical cancer. Next, we added anti-PD-1 mAb to our therapeutic recipe to assess the complementary role of immune checkpoint blockade in curbing tumor progression.

Methods

For this purpose, TC-1 tumor cells were injected into the mice models and treatment with NDV, iNDV, HA2, NDV-HA2, iNDV-HA2 began 10 days after tumor challenge and was repeated at day 17. In addition, PD-1 blockade was conducted by injection of anti-PD-1 mAb at days 9 and 16. Two weeks after the last treatment, sample mice were sacrificed and treatment efficacy was evaluated through immunological and immunohistochemical analysis. Moreover, tumors condition was monitored weekly for 6 weeks intervals and the tumor volume was measured and compared within different groups.

Results

The results of co-treatment with NDV and HA2 gene revealed that these agents act synergistically to induce antitumor immune responses against HPV-associated carcinoma by enhancement of E7-specific lymphocyte proliferation, inducement of CD8+ T cell cytotoxicity responses, increase in splenic cytokines and granzyme B, decrease in immunosuppressive cytokines and E6 oncogene expression, and upregulation of apoptotic proteins expression, in comparison with control groups. Moreover, incorporation of PD-1 blockade as the third side of our suggested therapy led to noticeable regression in tumor size and augmentation of cytokine responses.

Conclusions

The invaluable results of synergy between NDV virotherapy and HA2 gene therapy suggest that tumor-selective cell killing by oncolytic NDV can be enhanced by combining with FMG gene therapy. Moreover, the adjunction of the PD-1 blockade proves that checkpoint blockade can be considered as an effective complementary therapy for the treatment of cervical cancer.
X-linked muscular dystrophy in a Labrador Retriever strain: phenotypic and molecular characterisation
Authors: Barthélémy Inès , Calmels Nadège , Weiss Robert B. , Tiret Laurent , Vulin Adeline , Wein Nicolas , Peccate Cécile , Drougard Carole , Beroud Christophe , Deburgrave Nathalie , Thibaud Jean-Laurent , Escriou Catherine , Punzón Isabel , Garcia Luis , Kaplan Jean-Claude , Flanigan Kevin M. , Leturcq France , Blot Stéphane
Published: August 2020

Background

Canine models of Duchenne muscular dystrophy (DMD) are a valuable tool to evaluate potential therapies because they faithfully reproduce the human disease. Several cases of dystrophinopathies have been described in canines, but the Golden Retriever muscular dystrophy (GRMD) model remains the most used in preclinical studies. Here, we report a new spontaneous dystrophinopathy in a Labrador Retriever strain, named Labrador Retriever muscular dystrophy (LRMD).

Methods

A colony of LRMD dogs was established from spontaneous cases. Fourteen LRMD dogs were followed-up and compared to the GRMD standard using several functional tests. The disease causing mutation was studied by several molecular techniques and identified using RNA-sequencing.

Results

The main clinical features of the GRMD disease were found in LRMD dogs; the functional tests provided data roughly overlapping with those measured in GRMD dogs, with similar inter-individual heterogeneity. The LRMD causal mutation was shown to be a 2.2-Mb inversion disrupting the DMD gene within intron 20 and involving the TMEM47 gene. In skeletal muscle, the Dp71 isoform was ectopically expressed, probably as a consequence of the mutation. We found no evidence of polymorphism in either of the two described modifier genes LTBP4 and Jagged1. No differences were found in Pitpna mRNA expression levels that would explain the inter-individual variability.

Conclusions

This study provides a full comparative description of a new spontaneous canine model of dystrophinopathy, found to be phenotypically equivalent to the GRMD model. We report a novel large DNA mutation within the DMD gene and provide evidence that LRMD is a relevant model to pinpoint additional DMD modifier genes.
Exploring metacognitions in health anxiety and chronic pain: a cross-sectional survey
Authors: Rachor Geoffrey S. , Penney Alexander M.
Published: August 2020

Background

The occurrence of health anxiety (HA) in chronic pain is associated with adverse outcomes. As such, it is important to identify constructs that might influence HA and pain-related outcomes. Metacognitions are an emerging area of interest in both HA and chronic pain, but the relationship between the three factors has not been extensively examined. The current study sought to examine the role of metacognitions about health in HA and pain-related outcomes in chronic pain.

Methods

This study utilized a cross-sectional design. Undergraduate students with self-reported chronic pain (n = 179) completed online measures of HA, pain intensity, pain disability, and metacognitions about health.

Results

Regression analyses indicated that both metacognitions about biased thinking and that thoughts are uncontrollable predicted HA in chronic pain, while only metacognitions about biased thinking predicted pain-related disability beyond pain intensity.

Conclusion

Results demonstrate that HA and pain-related disability are not associated when taking metacognitions about health into account, suggesting that metacognitions about health at least partially account for the relationship between the two. Further, results suggest that metacognitions about biased thinking may independently influence HA and pain-related disability within chronic pain.
High-enthalpy hypersonic flows
Authors: Shang Joseph J. S. , Yan Hong
Published: August 2020

Nearly all illuminating classic hypersonic flow theories address aerodynamic phenomena as a perfect gas in the high-speed range and at the upper limit of continuum gas domain. The hypersonic flow is quantitatively defined by the Mach number independent principle, which is derived from the asymptotes of the Rankine-Hugoniot relationship. However, most hypersonic flows encounter strong shock-wave compressions resulting in a high enthalpy gas environment that always associates with nonequilibrium thermodynamic and quantum chemical-physics phenomena. Under this circumstance, the theoretic linkage between the microscopic particle dynamics and macroscopic thermodynamics properties of gas is lost. When the air mixture is ionized to become an electrically conducting medium, the governing physics now ventures into the regimes of quantum physics and electromagnetics. Therefore, the hypersonic flows are no longer a pure aerodynamics subject but a multidisciplinary science. In order to better understand the realistic hypersonic flows, all pertaining disciplines such as the nonequilibrium chemical kinetics, quantum physics, radiative heat transfer, and electromagnetics need to bring forth.
Mentoring Structures and the Types of Support Provided to Early-Year Undergraduate Researchers
Authors: Ceyhan Gaye D. , Tillotson John W.
Published: August 2020

This study investigated undergraduate researchers’ perspectives on mentoring structures and the support provided to them in their first and sophomore years. Participants reported receiving different types of support from faculty and postgraduates depending on their mentoring structures and the amount of research experience they gained.
Racial Disparities of Adrenalectomy
Authors: Holoubek Simon A , Maxwell Jessica , Fingeret Abbey L
Published: August 2020

Purpose

Racial disparities of surgical outcomes have been demonstrated for a variety of operations. We sought to determine whether minority status is associated with disparate care for adrenalectomy.

Methods

This study is a retrospective database review of the Collaborative Endocrine Surgery Quality Improvement Program (CESQIP) from January 1, 2014 through April 30, 2018. Primary outcome was complication rate. Secondary outcomes were length of stay and surgeon experience. Minority status was defined as Black or Hispanic and outcomes were compared with White patients.

Results

For the study period, 1141 patients who underwent adrenalectomies were included, of whom 69.9% were White and 22.6% minority. The minority patients were significantly younger with higher rates of diabetes mellitus. Minority patients had higher rates of complication and longer length of stay. Minority patients were more likely to have an adrenalectomy by a low-volume surgeon. In multivariate logistic regression, minority status remained associated with complication rate.

Conclusions

Minority patients undergoing adrenalectomy have higher rates of complication and longer lengths of stay when controlling for common comorbidities. Minority patients have decreased access to high-volume surgeons.
Time to make surgery greener: waste reduction in the operating theatre
Authors: Winter George
Published: August 2020

Sustainability persists as a key issue in all aspects of society, with increasing urgency. George Winter discusses the environmental impact of operating theatres and the initiatives being implemented to reduce surgical waste output.
Chronic constipation: building pathways for better bowel management
Authors: Emmanuel Anton
Published: August 2020

Constipation is often seen as a minor health problem, but when it becomes chronic it can have a major human impact on the patient and a financial impact on health services. Anton Emmanuel discusses the need for more effective methods of managing bowel health in NHS services.
Feasibility of use of the anxiety thermometer in antenatal services
Authors: Richens Yana , David Anna L , Llahana Sofia , Gessler Sue , James Catherine P , Liao Lih-Mei
Published: August 2020

Of the 102 women approached, 101 (99%) completed the anxiety thermometer (AnxT). The women were aged between 22–44 years (mean age 34.5 years); about half were primigravida and half multigravida. Almost two-thirds rated their current anxiety as four or above out of a maximum of 10. The most frequently reported concern was health of baby, followed by fears and worries, tiredness, and sleep problems. The high participation rate suggests that the AnxT can be developed to screen anxiety and elicit perinatal and related concerns to facilitate consultation and appropriate triaging. The problem checklist was refined based on the current results.
Helping student midwives become safe practitioners: effective teaching of cardiotocograph interpretation
Authors: Cull Joanne
Published: August 2020

It is crucial that, at the point of registration, midwives can competently interpret intrapartum cardiotocographs (CTGs). It is therefore important that practice assessors are confident teaching the safe and accurate interpretation of CTGs to the students they support. This paper uses a case study to examine how CTG interpretation can be taught most effectively. Humanistic learning theories can be used to create a psychologically safe-learning environment which is enjoyable for both the student and the practice assessor. Using a taxonomy of learning enables midwives to help the student develop higher order thinking skills, while understanding the learning style of that individual student allows midwives to incorporate tailored teaching in their clinical work. In addition to providing feedback, it is beneficial to encourage self-reflection and the student midwife's newly learned skills can be solidified by peer teaching.
Radiation therapy in veterinary medicine: a practical review
Authors: Del Portillo Isabel , Sesanto Christine , Parys Magdalena , Serra Juan Carlos
Published: August 2020

Radiotherapy is a treatment modality based on the use of high-energy rays to kill neoplastic cells, which has become an integral therapeutic tool in veterinary medicine. Radiotherapy may be an effective treatment for tumours that are not easily managed with surgery or with chemotherapy, even for patients with advanced-stage neoplasia. Novel uses of radiotherapy include rescue therapy for specific benign conditions that are refractory to conventional therapy. Acute and late toxicities depend on the prescribed protocol as well as sensitivity and volume of the normal tissue in or near the radiation field. The potential risks associated with the treatment should be fully discussed with owners before starting radiotherapy. New hardware and software technology has drastically advanced the ability to precisely target tumours, improving treatment efficacy and safety.
Xenophobia among University Students: Its Relationship with Five Factor Model and Dark Triad Personality Traits
Authors: Kocaturk Metin , Bozdag Faruk
Published: August 2020

Xenophobia, being hostile to foreigners and feeling fear of them, is considered as hating and having prejudices against the people of other nations. It is noticed that with the increase of migration movements on a global scale in recent years, xenophobia has become one of the more critical subjects in the scientific world. Determining the relationships between xenophobic attitudes and personal traits is considered as one of the important steps in developing relationships especially among people from different cultures. By detecting positive personality traits and negative personality traits associated with xenophobia, interpersonal relationships can be developed. Accordingly, in the current study, it is aimed to determine the relationships between xenophobia and personality traits (neuroticism, extraversion, openness to experience, agreeableness and conscientiousness, and Machiavellianism, narcissism and psychopathy). For this purpose, data were collected from 422 (342 females, 80 males) university students via the data collection tools, which are “Xenophobia Scale”, “Adjectives Based Personality Test” and “Dirty Dozen Scale”. The data were analyzed by stepwise regression technique. As a result of the analyzes, it has been observed that agreeableness, which is among the five-factor personality traits, and psychopathy and narcissism, which are among the dark triad-personality traits predicted xenophobia significantly. Accordingly, it was determined that the agreeable people had lower levels of xenophobic attitudes. Psychopathy and narcissism personality traits have been observed to lead to higher levels of xenophobic attitudes.
Agricultural valorization by biotransformation of fish wastes combined with grape marc and molasses
Authors: Lakhal Dounia , Bahlaouan Bouchaib , Boutaleb Nadia , Bennani Mohamed , El Antri Said
Published: August 2020

Since the advent of agriculture, organic wastes have been used to fertilize agricultural soils. The sustainability of the recovery of these wastes depends on the quality of the products developed in order to meet the expectations of the agricultural profession. The objective of our study was to evaluate the quality of the biotransformation of a ternary mixture of industrial waste: fish waste, molasses, and grape marc. Several balanced mixtures were developed and underwent natural biotransformation for two weeks to produce a fertilizer of good nutritional and microbiological quality. Quality control parameters (pH, conductivity, dry matter, phosphorus, nitrogen, potassium, carbon, etc.) were monitored during the time stipulated for biotransformation.

The results showed that the bio-fertilizer generated from the mentioned wastes is characterized by good agronomic quality (rich in phosphorus, nitrogen, and potassium), mature, with a stable pH and had an excellent hygienic condition, due to the absence of spoilage microorganisms, which would constitute a major obstacle to the adoption of this practice.

The fertilization test showed that our product is more interesting than commercial fertilizer. Triangular surfaces of iso-responses are established to identify the relevant formulations leading to a product of specific interest to build in practice a predictive operational model for industrial waste management. The biotransformation of a mixture consisting of approximately 50% of fish waste, 12.5% molasses, and 37.50% grape marc is an optimal formulation to generate a product rich in the nutrients essential for optimal growth plants (nitrogen, phosphorus, and potassium). The formulas do not integrate the grape marc was the most unfavorable mixtures from their efficacy and/or health safety criteria.
Security-enhanced optical cryptosystem using nonergodic scrambling phase mask
Authors: Dou Shuaifeng , Shen Xueju , Zhou Bing , Lin Chao , Liu Jie
Published: August 2020

Cryptanalysis revealed a security flaw in the double random phase encoding (DRPE) system, and the original image was recovered via a ciphertext-only attack. In this paper, a nonergodic scrambling phase mask (NESPM) is designed, and a security-enhanced cryptosystem is established by replacing the bonded random phase mask (RPM) in the DRPE system with the designed NESPM. The original image in the security-enhanced cryptosystem is optically scrambled at “macropixel” level by the bonded NESPM, instead of being diffused by the RPM, as in the DRPE system. Due to such a scrambling operation, the ergodic property of the Fourier-plane speckle pattern in the designed cryptosystem is removed, and the original image cannot be recovered via the attack. Experimental results demonstrate that the designed cryptosystem is resistant to the attack. Security enhancement is achieved.
Reseña de Salles, R.; Molina Ayala, J. Alejandro de Afrodisia. De la mixtura y el crecimiento (2019)
Authors: Valencia Constantino Genaro
Published: August 2020

Reseña de Salles, R.; Molina Ayala, J. Alejandro de Afrodisia. De la mixtura y el crecimiento (2019).
A idade bíblica dos juízes sem a letra ‘g’
Authors: Santos Júnior Cristóvão José Dos
Published: August 2020

Este trabalho consiste na primeira tradução lipogramática e na primeira já realizada para a língua portuguesa do Livro VII da obra De aetatibus mundi et hominis, creditada ao escritor tardio e africano Fulgêncio, o Mitógrafo (final do séc. V – início do séc. VI d.C.). A De aetatibus se trata de um lipograma consecutivo que possui um prólogo e outros 14 Livros, com constrição nas 14 letras iniciais do alfabeto fulgenciano. Nesta sétima seção da obra, Fulgêncio discute a idade bíblica dos juízes, evitando o emprego de unidades lexicais que contenham a letra ‘g’, o que foi cultivado no texto tradutório proposto, que foi desenvolvido a partir da edição crítica efetuada por Rudolf Helm (1898).
On the Will of the People: Notes on the Political “Theory” of Populism
Authors: Offe Claus
Published: August 2020

The “will of the (national) people” is the ubiquitously invoked reference unit of populist politics. The essay tries to demystify the notion that such will can be conceived of as a unique and unified substance deriving from collective ethnic identity. Arguably, all political theory is concerned with arguing for ways by which citizens can make e pluribus unum—for example, by coming to agree on procedures and institutions by which conflicts of interest and ideas can be settled according to standards of fairness. It is argued that populists in their political rhetoric and practice typically try to circumvent the burden of such argument and proof. Instead, they appeal to the notion of some preexisting existential unity of the people’s will, which they can redeem only through practices of repression and exclusion.
Maternal iron homeostasis: effect on placental development and function
Authors: Roberts Hannah , Bourque Stephane L , Renaud Stephen J
Published: August 2020

Iron is an essential mineral that participates in oxygen transport, DNA synthesis and repair, and as a cofactor for various cellular processes. Iron deficiency is the most common nutritional deficiency worldwide. Due to blood volume expansion and demands from the fetal–placental unit, pregnant women are one of the populations most at risk of developing iron deficiency. Iron deficiency during pregnancy poses major health concerns for offspring, including intrauterine growth restriction and long-term health complications. Although the underlying mechanisms remain unclear, maternal iron deficiency may indirectly impair fetal growth through changes in the structure and function of the placenta. Since the placenta forms the interface between mother and baby, understanding how the placenta changes in iron deficiency may yield new diagnostic indices of fetal stress in affected pregnancies, thereby leading to earlier interventions and improved fetal outcomes. In this review, we compile current data on the changes in placental development and function that occur under conditions of maternal iron deficiency, and discuss challenges and perspectives on managing the high incidence of iron deficiency in pregnant women.
First record of the genus Syritta Le Peletier & Audinet-Serville, 1828 (Diptera, Syrphidae) from the West Indies
Authors: Mengual Ximo , de Soto Molinari Carlos
Published: August 2020

We report the genus Syritta Le Peletier and Audinet-Serville, 1828 (Diptera: Syrphidae) from West Indies for the first time. A female of the synanthropic species Syritta flaviventris Macquart, 1842 was photographed in the Refugio de Vida Silvestre Río Higuamo, Dominican Republic. This species was introduced in the American continent by human expansion.
Det mandlige herredømme i middelhavskulturen ifølge Pierre Bourdieu
Authors: Petersen Karin Anna , Callewaert Staf
Published: August 2020

Abstract

Den feministiske kritiks mistanke om, at mandlige skrifter om forskellen mellem de to køn omfatter fordomme, er berettiget. Den mandlige analytiker kan ud fra en forsvarsholdning komme til at tilskrive de agenter, han analyserer, forudsætninger og fordomme, som i virkeligheden er de forudsætninger og fordomme, han selv går ud fra i sin analyse. Men frem for alt er forskellen mellem de to køn en institution, som gennem tusinder af år er indskrevet i de objektive, sociale strukturer og de subjektive mentale strukturer sådan, at forskeren er tvunget til at bruge dét som erkendelsesmidler, der burde være formål for analysen, nemlig de kategorier vi bruger for at tænke problemet.

Teksten er en resumerende fortolkning af Pierre Bourdieus artikel om det mandlige herredømme: Bourdieu, P (1990): La Domination Masculine. Actes de la recherche en sciences socialcs, 84, Paris 2-31. Fortolkningen prøver med nogle minimale kommentarer at indfange de store linjer i opfattelsen.
Plastic surgery of extensive soft tissue defects of the lower leg in children with the use of a parotid flap after its prefabrication with tissue expanders (preliminary report)
Authors: Filippova Olga V. , Govorov Anton V. , Proshchenko Yaroslav N. , Afonichev Konstantin A. , Galkina Natalia S.
Published: August 2020

Background. Extensive deep soft tissue defects in children are an indication for the microsurgical reconstruction using autotransplantation of a tissue complex. The use of a flap prefabrication before their microsurgical transplantation to various segments and areas is a promising approach in reconstructive surgery.
Aim. The aim of this study was to evaluate the possibilities and immediate results of plastic surgery of extensive soft tissue defects of the lower leg with a tissue complex, after its prefabrication with a tissue expander, and the state of the donor area in different surgical treatment options.
Materials and methods. Six patients aged 13 2.3 years were operated on for deep scar deformities of the lower leg and foot. For plastic surgery, a pericarpial flap was used. In two patients, the flap was prefabricated with tissue expanders at a volume of 720 ml. After filling the expander, the second stage of surgical treatment was performed. First, the expander was removed. Next, the flap on the artery surrounding the scapula was isolated. Last, it was transplanted into a soft tissue defect of the lower leg with the imposition of microvascular anastomoses. A layer-by-layer suture was applied to the donor wound. The Vancouver scale was used to assess the quality of the scar tissue in the donor area.
Results. The removal of the tissue complex after the prefabrication with expanders made it possible to perform plastic surgery of extensive soft tissue defects of the lower leg in one stage of surgical treatment with the application of a cosmetic suture in the donor area. There were no complications in the postoperative period.
At the examination after six months, patients who did not undergo flap prefabrication complained of cosmetic defects and discomfort when moving in the donor area.
The evaluation of the quality of scar tissue by the Vancouver scale showed that the scars in patients after flap prefabrication were similar to optimal (total score in two patients is 2). In two patients without flap prefabrication, the total score was 7, and in two patients, it was 9, which indicated unsatisfactory cosmetic parameters of the postoperative scar.
Conclusion. The prefabrication of a tissue complex using tissue expanders before microsurgical transplantation enables the collection of a large volume of tissue for plastic surgery of extensive defects. It also reduces the risk of trophic complications in the postoperative period and creates optimal conditions for closing the donor site.
Osmanlı Sanayisi Hizmetinde Kırk Yıl: İngiliz Mühendis Frederick William Taylor’un Hayat Hikâyesi (1807-1875)
Authors: Soyluel Serdal
Published: August 2020

Bu çalışmada Osmanlı Devleti’nde modern sanayi kurma girişimlerinin başladığı
sıralarda İngiliz Hükümeti tarafından İstanbul’a gönderilen ve İngiltere’ye yaptığı
birkaç seyahat dışında ömrünün geri kalanını İstanbul’da geçiren İngiliz mühendis
Frederick William Taylor’un hayat hikâyesi anlatılmaktadır. Taylor, henüz genç bir
mühendisken geldiği İstanbul’da yerli sanayinin modernleştirilmesi çabalarına bizzat
tanıklık eder. İnşaat mühendisliğinin yanı sıra, iş tecrübesini buhar makineleri
imal eden bir fabrikada demir dökümü, makine üretimi ve kurulumu ile bunlara
ait binaların inşasında kazandığından döküm işleri ve mekanik konusunda bir
döküm ustası ve makine mühendisi kadar bilgi birikimine sahipti. Aynı zamanda
Avrupa’da yeni gelişmekte olan modern endüstriyel mimarî alanında da uzman bir
mimar olan Taylor’un bu vasıfları onu Tanzimat Devri devlet ve askerî ricâli için Osmanlı sanayisinin ihyâsı çalışmalarında vazgeçilmez bir unsur kılmıştı. Başta
Tersâne-i Âmire ve Tophâne-i Âmire olmak üzere pek çok devlet imalathânesinin
modernizasyonunda Frederick William Taylor’un imzasını görmek mümkündür.
Makalenin amacı, bu denli önemli işlere imzasını atmış ve Osmanlı Devleti için sıradan
bir Avrupalı uzmandan çok daha fazlası olan birinin pek bilinmeyen hayatının
karanlık yönlerini aydınlatmak ve bu sayede modernize edilmeye çalışılan Osmanlı
sanayisinde olup bitenlere bir nebze ışık tutmaktır.
Laramanlar: Gizli Hristiyan Arnavutların Mihaliç’e Sürgünü (1846-1848)
Authors: Ahbab Yakup
Published: August 2020

Osmanlı Devleti için 19. yüzyıl, umutsuz zamanlarda ümitsiz tedbirlerin alındığı
dığı bir dönem olmuştur. Tanzimat Fermanı’nın uygulanmaya başlanmasıyla birlikte
Osmanlı Devleti’nde yeni bir dönemin başladığı kabul edilmektedir. Osmanlı Devleti
bu döneme ayak uydurmakta zorlanmıştır. Doğal olarak bu yeni dönem yeni
politik sorunları da beraberinde getirmiştir. Özellikle Sırp ve Yunan isyanları, Balkan
topluluklarını patlamaya hazır hale getirmeye yetmiştir. Tam bu dönemde ilan edilen
Tanzimat Fermanı da toplum içerisindeki bu gerilimi azaltmaya çare olamamıştır. Bu
çerçeveden bakıldığında gizli din taşıyanlar Tanzimat Fermanı’nın akabinde kendilerini
ifşa etmişlerdir. Toplumun sinir uçlarına dokunan bu davranışlar, muhafazakâr
kesimden çok sert tepki çekmiştir. Hükümet ise Tanzimat Fermanı’nın gerekliliklerini
yerine getirme gayretindeydi. Lakin ne muhafazakâr kesim ne de Avrupalı Devletleri
memnun etmek kolay olmamıştır. Bu makalede gizli Hristiyan Arnavutların
kendilerini ifşa etmeleri ve sonrasında yaşananlar, Osmanlı arşiv belgeleri, yerli ve
yabancı kaynaklar eşliğinde anlatılmıştır.
Adjetivos stage-level e individual-level em construções depictivas
Authors: Ferreira Elisabete
Published: August 2020

Neste trabalho, revejo a proposta de análise apresentada em Ferreira (2017) para construções de predicação secundária depictiva, como O João leu a carta cansado. Mais especificamente, rejeito a hipótese de Ferreira (2017) de que, em tais sentenças, nas quais ocorreria adjunção de uma small clause aspectual à oração matriz, uma categoria funcional Asp atribuiria a propriedade stage-level a um adjetivo como cansado. Neste artigo, defendo que a relação entre Asp e o adjetivo não seja de atribuição de propriedade, mas de compatibilidade de traços semânticos na seleção, e que o adjetivo entraria na derivação carregando a informação de que veicula uma propriedade transitória ou permanente. Nesse sentido, suponho que essas construções de predicação secundária possam apresentar um dos dois tipos de Asp: um que entra na derivação com um subconjunto de traços semânticos [+pers], que denota persistência temporal e seleciona adjetivos individual-level, ou um que entra na derivação com o subconjunto [–pers], que denota eventualidade temporária e seleciona adjetivos stage-level. Em minha argumentação, recorro a McNally (1993) e a Cinque (2010): a primeira, para tratar de predicações secundárias com predicados individual-level e da influência da pragmática nesses contextos; o último, para tratar brevemente de adjetivos stage-level e individual-level no âmbito do DP.
ELDERLY SCREENING IN SONGGON BANYUWANGI 2019
Authors: Hakim Lukman , Erlangga Wildan Anugrah , Adi Pandu Satriya , Septiana Fitri Nurina , Arianti Emilia Eka , Qualisa Prafidina , Lamara Ariikah Dyah , Meitavany Estya Nadya , Fatimah Niswah Silmi , A Ulinnuha Qurrota , Sulistiawati Sulistiawati
Published: August 2020

Health care efforts for the elderly to keep the elderly healthy, independent, active and productive socially and economically , to realize this, the government is obliged to guarantee the availability of health service facilities and facilitate the development of the elderly group. The aims to identify factors that affect the achievement of health care coverage of the elderly.  This  was a qualitative descriptive study. This research was conducted in Songgon District . The target sample was the elderly residents and elderly Posyandu cadres. Data collection instruments using questionnaires. This study used primary data. Univariate analysis to determine the distribution using SPSS and Excel tools.  84% of elderly people knew about screening. The coverage of elderly screening was still low. From the results of research on community therapy that could be done was cadre training, reporting of the elderly, and Extension of Posyandu Elderly by Cadres for the Community
Symmetrical Current and Massive Gauge Bosons in SM4
Authors: Verma Aayush
Published: August 2020

This note will be brief attention to an unknown current in SM4 Field based on disintegrating the Lagrangian of quarks in SM4 into four parts. It is shown that the current breaks while interacting with the quarks and makes the quarks to not interact with fourth-generation quarks. This note also shows that gauge bosons are produced while these currents symmetry break and provides the service as mediators.
Information Circulation in The Advanced Neural Activities of Central Neural System
Authors: Ma Fayang
Published: August 2020

Long-Term Potentiation(LTP) and Long-Term Depression(LTD) are two major forms of synaptic plasticity, which are also two well-know functional and unit activities involved in high advanced central neural system(CNS) activities, like memory. But we still know little about how the advanced CNS activities are organized in the brain and in the level of organism. Based on the current understanding and experimental evidence of neurology, we propose the term “Information Circulation” to summarize the current understandings for advanced CNS activities, and we define it as separately input neural signals finally converge in different levels of CNS and interact with each other, then neural information are circulated and processed in different levels of CNS to give out orders for next body actions. This review provides a detailed description for the functional organizations of advanced CNS activities in the term of Information Circulation. This article outlines the receiving of outside stimulation and transmission of neural information, especially transmission and procession of visual bioelectrical signals, then we described neural circuits of Information Circulation in advanced CNS activities, the corresponding specificity and dynamic properties of neural circuits, different sensation linkages, and neural synchronization for information circulation to produce consciousness in CNS. In conclusion, Information Circulation is defined as an important signature involved in advanced CNS activities.
PENGARUH KECERDASAN EMOSIONAL DAN GAYA KEPEMIMPINAN DEMOKRATIS TERHADAP PERFORMANSI KEPALA RA PEREMPUAN DI KABUPATEN PATI
Authors: Kamto Kamto
Published: August 2020

This study aims to menaganlisisi influence of emotional intelligence, and the democratic leadership style to the performance of the head of RA Raudlotul women in Pati regency. Respondents in this study is the head Rayang amounted to 221 people with a sample of 135 people. The analysis used is multiple regression with SPSS 17. Results and discussion shows that 1) The value of correlation (r) of 0.188 indicates the relationship between emotional intelligence and the performance of the head of RA female Raudlatul 2) The value of the correlation (r) of 0.206 indicates a relationship between the democratic leadership and the performance of the head of RA Raudlatul women. 3) Emotional intelligence and the democratic leadership together or simultaneous positive and significant impact on the performance of the head of RA Raudlatul women in Pati regency that F test value of 5.356 and sig. at 0.006. Emotional intelligence means the better and it will be followed democratic leadership performance improvement Raudlatul head Athfal women in Pati regency.