bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of serum allergen-specific IgE levels in horses with seasonal allergic dermatitis and recurrent airway obstruction in Spain
Authors: Marteles Diana , Odriozola Laura , Verde María Teresa , Conde Tomás , Fernández Antonio
Published: March 2019

Allergic conditions are prevalent equine diseases that can be diagnosed by clinical examination alone, but definitive diagnosis is more likely with laboratory testing. The ELISA Allercept© test was used to analyse the serum samples of 73 horses with allergic diseases. Sixty-one horses (83.5%) had allergen-specific IgE levels ≥ 150 ELISA Units (EU), the cut-off defined by the assay. Fifty-four horses had allergic dermatitis (AD) with high IgE levels to Tyrophagus putrescentiae (51.9%), Rumex crispus (48.1%), Tabanus (46.3%) and Dermatophagoides farinae/ D. pteronyssinus (40.7%). Seven horses with recurrent airway obstruction (RAO) had a high prevalence of T. putrescentiae (85.7%), followed by that of Acarus siro (57.1%) and D. farinae/D. pteronyssinus (57.1%). Horses affected with RAO had more positive reactions to mites (2.22 ± 0.84) than did horses with AD (1.51 ± 0.61, P < 0.05). A strong correlation of serum allergen-specific IgE level was found between Culex tarsalis and Stomoxys (r = 0.943) and between Dactylis glomerata and both Secale cereale (r = 0.79) and R. crispus (r = 0.696). These results indicate that among horses with allergic diseases in Spain, ELISA tests demonstrated a high prevalence of serum allergen-specific IgE in response to mites. Our study emphasises the importance of laboratory testing and updating allergy panels to improve the likelihood of a definitive diagnosis and the identification of allergens that should be included in allergic disease treatment.
Prevalence and risk factors of Neospora caninum infection in ovine flocks of central-western Mexico
Authors: Romo-Gallegos Jesús Manuel , Cruz-Vázquez Carlos , Medina-Esparza Leticia , Ramos-Parra Miguel , Romero-Salas Dora
Published: March 2019

This study, carried out in 13 sheep flocks of central-western Mexico, aimed to identify the prevalence of anti-N. caninum antibodies, to develop a risk analysis of the infection and to estimate the prevalence of parasite DNA in blood. A total of 368 serum and blood samples were subjected to ELISA and PCR tests, respectively, and the association between the prevalence of antibodies and some management factors was estimated. The overall prevalence of anti-N. caninum antibodies was 13.5% [50/368; 95% confidence interval (CI) 10–17], ranging from 2.7 to 90% per flock, and 92% of the farms had seropositive animals. In ewes the prevalence was 14% (48/348, 95% CI 10–17) and in rams 10% (2/20; 95% CI 1– 33). The mean prevalence of Neospora DNA in blood was 27% (99/368, 95% CI 22–31), implying a range between 16 and 82%. In rams, the prevalence was 5% (1/20 95% CI 2–26), while in ewes it was 28% (98/348, 95% CI 23–33). The agreement between the tests was k = 0.19. The presence of other domestic animal species in the farms [odds ratio (OR) 4.4] and the consumption of placental debris, fetuses and stillborn lambs by dogs living in the farms (OR 5.8) were demonstrated to be risk factors.
Immunopathological findings in a cat with auricular chondritis
Authors: Meziara Wilson Tais , Machado Mizael , De Sousa Davi Emanuel Ribeiro , Braúna Tainã , Torres Neto Rafael , Laufer-Amorim Renée , Szabó Matias Pablo Juan , De Castro Marcio Botelho
Published: March 2019

At clinical examination, a 5-year-old male domestic short-haired cat exhibited painful swelling and erythema of the pinnae of both ears. Microscopically, the lesions on both pinnae were composed of diffuse granulomatous chondritis with degeneration and necrosis of the pinnal cartilage. Numerous mast cells were also observed within and surrounding the inflammatory lesion. Immunohistochemistry showed a mixed inflammatory infiltrate characterised by the predominance of macrophages (CD68+, MAC 387+ and Lysozyme+), T lymphocytes (CD3+), some B lymphocytes (CD79α+) and neutrophils. Immunopathological characterisation of the lesion showed a granulomatous inflammation profile and suggests that the morphological changes and immunopathogenesis of auricular chondritis in cats presents a similarity with relapsing polychondritis in humans.
A phenomenology of subjectively relevant experiences induced by ayahuasca in Upper Amazon vegetalismo tourism
Authors: Wolff Tom John , Ruffell Simon , Netzband Nigel , Passie Torsten
Published: March 2019

Aims

This heuristic study reports observations on the phenomenology of ayahuasca experiences of nine foreign tourist participants of an ayahuasca retreat in Peru.

Methods

Narrative interviews, reflecting individual experiences after ayahuasca “night ceremony,” have been analyzed by qualitative content analysis using a data-driven strategy in order to extract themes and categories inherent in the interviews. Previously, a demographic questionnaire was given. The dose–response connection was uncontrolled, which is typical for this naturalistic setting.

Results

The typical structure of spontaneously reported experiences includes: personal preparation, physical symptoms, visual phenomena, cognitive and emotional phenomena, reactions of the individual within the psychedelic “world” as well as within ordinary reality, and appraisal to the process. Emotional reactions were subsumed under pleasant (psychotherapeutic “target emotions” and hedonistic emotions) and unpleasant emotions. For a majority, the presence of psychotherapeutic target emotions seemed to involve the presence of unpleasant emotions in the same session – possibly as transitional emotional states.

Conclusions

This suggests that psychodynamic processes, for example, possible activation of emotional conflicts – can take place spontaneously, during ayahuasca intake in this particular setting. Some participants attributed symbolic meaning to the visionary content, which was more likely to take place in psychotherapeutically motivated clients. The specific setting influence as well as corresponding expectations of the participants in native wisdom could have considerable influence on experiences and interpretations, such as communication with entities as well as receiving personal teachings.
Clinically Integrated Molecular Diagnostics in Adenoid Cystic Carcinoma
Authors: Thierauf Julia , Ramamurthy Nisha , Jo Vickie Y. , Robinson Hayley , Frazier Ryan P. , Gonzalez Jonathan , Pacula Maciej , Dominguez Meneses Enrique , Nose Vania , Nardi Valentina , Dias-Santagata Dora , Le Long P. , Lin Derrick T. , Faquin William C. , Wirth Lori J. , Hess Jochen , Iafrate A. John , Lennerz Jochen K.
Published: March 2019

Background

Adenoid cystic carcinoma (ACC) is an aggressive salivary gland malignancy without effective systemic therapies. Delineation of molecular profiles in ACC has led to an increased number of biomarker-stratified clinical trials; however, the clinical utility and U.S.-centric financial sustainability of integrated next-generation sequencing (NGS) in routine practice has, to our knowledge, not been assessed.

Materials and Methods

In our practice, NGS genotyping was implemented at the discretion of the primary clinician. We combined NGS-based mutation and fusion detection, with MYB break-apart fluorescent in situ hybridization (FISH) and MYB immunohistochemistry. Utility was defined as the fraction of patients with tumors harboring alterations that are potentially amenable to targeted therapies. Financial sustainability was assessed using the fraction of global reimbursement.

Results

Among 181 consecutive ACC cases (2011–2018), prospective genotyping was performed in 11% (n = 20/181; n = 8 nonresectable). Testing identified 5/20 (25%) NOTCH1 aberrations, 6/20 (30%) MYB-NFIB fusions (all confirmed by FISH), and 2/20 (10%) MYBL1-NFIB fusions. Overall, these three alterations (MYB/MYBL1/NOTCH1) made up 65% of patients, and this subset had a more aggressive course with significantly shorter progression-free survival. In 75% (n = 6/8) of nonresectable patients, we detected potentially actionable alterations. Financial analysis of the global charges, including NGS codes, indicated 63% reimbursement, which is in line with national (U.S.-based) and international levels of reimbursement.

Conclusion

Prospective routine clinical genotyping in ACC can identify clinically relevant subsets of patients and is approaching financial sustainability. Demonstrating clinical utility and financial sustainability in an orphan disease (ACC) requires a multiyear and multidimensional program.

Implications for Practice

Delineation of molecular profiles in adenoid cystic carcinoma (ACC) has been accomplished in the research setting; however, the ability to identify relevant patient subsets in clinical practice has not been assessed. This work presents an approach to perform integrated molecular genotyping of patients with ACC with nonresectable, recurrent, or systemic disease. It was determined that 75% of nonresectable patients harbor potentially actionable alterations and that 63% of charges are reimbursed. This report outlines that orphan diseases such as ACC require a multiyear, multidimensional program to demonstrate utility in clinical practice.
The Boundaries of the Djamaat: The Particular Features of Dangestan’s Translocal Communities in the Context of Migration Flows Within the Russian Federation
Authors: Капустина Екатерина Леонидовна
Published: March 2019

This paper analyses the contemporary structure and functioning of Dagestan’s rural communities in a context of internal Russian migration, particularly to the cities of Western Siberia. The concepts of transnationalism and translocality are deployed as a theoretical framework to analyse the migrant and his social world without detaching ourselves from the donor community, the djamaat. It is argued that the Dagestan rural community, in the course of the migration processes of recent decades, can no longer be viewed merely as a local social entity. A new translocal community has emerged, organized on the principle of the 'Global Village', that consists of migrants, their family members and non-migrants remaining in the home villages. Translocal migrants, existing simultaneously in several geographically separated points, continue to construct their identity and their social networks, a process that fosters a sense of belonging to a Dagestani village. The donor rural community is an important space where migrants can demonstrate personal successes and new entrepreneurial and philanthropic economic activities. Migrants invest not only in their own households but also help their native villages as a whole through entrepreneurial activity and financial support. In addition, the key moments of life remain rooted in the village. Migrants prefer to find a marriage partner from their home village. The home village is also seen to be the only acceptable burial place for deceased migrants. A major role in the consolidation of a translocal djamaat is played by Internet resources such as social networks and messenger programmes, which construct social networks and maintain communication among fellow countrymen in real time. This preference for preserving ties to one’s rural locality even after resettlement out of the village and the Republic of Dagestan, as well as the maintenance of translocal links, allow us to speak of a new social entity: the translocal community.
Переход во взрослую жизнь: сравнение Северного Кавказа с общероссийской картиной
Authors: Митрофанова Екатерина Сергеевна
Published: March 2019

Статья представляет анализ количественных данных, касающихся специфики процесса взросления индивида на Северном Кавказе. Исследование построено на материале общероссийского репрезентативного обследования «Человек, семья, общество», проведенного в 2013 г. В фокус наблюдения попали поколения 1970–1994 гг. рождения. Мы сравнили наступление событий, маркирующих взросление у жителей северокавказских республик с регионами России по следующим характеристикам: по частоте, возрасту, интенсивности и последовательности наступления событий. События, маркирующие взросление, разбиты на две группы: социодемографические(первая интимная близость, первое партнерство, первый брак и первое деторождение) и социоэкономические (завершение получения образования, первое отделение от родителей и первое трудоустройство). Показано, что на Северном Кавказе сохраняются более традиционные модели перехода во взрослую жизнь, нежели в остальных российских регионах: события в брачной и репродуктивной сферах наступают с более короткими интервалами, то есть сильно обуславливают друг друга; браки остаются превалирующей формой совместного проживания; деторождение происходит в более раннем возрасте и интенсивнее, чем в других регионах; гендерные различия в социодемографическом поведении почти отсутствуют, а в социально-экономическом – выражены сильнее, чем в другихрегионах. Тем не менее представленные данные указывают и на некоторые признаки демографической модернизации. Так, у молодых северокавказских мужчин (но не у женщин) наблюдается большее по сравнению с предшествующими поколениями разнообразие в последовательности событий, связанных с взрослением, то есть единая для всех норма заменяется разнообразием жизненных путей.
Energy Security Concerns versus Market Harmony: The Europeanisation of Capacity Mechanisms
Authors: Leiren Merethe Dotterud , Szulecki Kacper , Rayner Tim , Banet Catherine
Published: March 2019

The impact of renewables on the energy markets–falling wholesale electricity prices and lower investment stability–are apparently creating a shortage of energy project financing, which in future could lead to power supply shortages. Governments have responded by introducing payments for capacity, alongside payments for energy being sold. The increasing use of capacity mechanisms (CMs) in the EU has created tensions between the European Commission, which encourages cross-country cooperation, and Member States that favour backup solutions such as capacity markets and strategic reserves. We seek to trace the influence of the European Commission on national capacity markets as well as learning between Member States. Focusing on the United Kingdom, France and Poland, the analysis shows that energy security concerns have been given more emphasis than the functioning of markets by Member States. Policy developments have primarily been domestically driven, but the European Commission has managed to impose certain elements, most importantly a uniform methodology to assess future supply security, as well as specific requirements for national capacity markets: interconnectors to neighbouring countries, demand side responses and continuous revision of CMs. Learning from other Member States’ experiences also play a role in policy decisions.
Hard or Soft Governance? The EU’s Climate and Energy Policy Framework for 2030
Authors: Oberthür Sebastian
Published: March 2019

This article investigates the stringency of EU climate and energy governance along the soft-hard continuum as a key determinant of its ability to achieve its ambitions. It introduces four criteria for a systematic and differentiated assessment of the bindingness/stringency of legislative instruments and governance frameworks, namely: (1) formal legal status, (2) the nature of the obligations (substantive—procedural), (3) their precision and prescriptiveness, and (4) the means for effecting accountability and effective implementation. The application of this assessment framework to the EU’s Climate and Energy Policy Framework for 2030 in comparison with the preceding 2020 Framework and the international Paris Agreement on climate change demonstrates the added value of this approach. The focus is on regulations, adopted in 2018, regarding greenhouse gas emissions, renewable energy (RE), and energy efficiency as well as the surrounding framework for planning, reporting, monitoring, and enforcement. The EU’s 2030 Framework scores high on the four criteria. Despite implementing the comparatively soft Paris Agreement, it does not fall behind the stringency of the 2020 Framework, as the abandoning of binding national targets for RE is balanced by strengthened obligations to prepare national plans, long-term strategies, and regular progress reports, as well as the enhanced monitoring and supervisory powers of the European Commission. While actual delivery will not least depend on how the Commission will use its established and newly acquired powers and tools, the 2030 Framework reinforces EU interest in strengthening international climate governance under the Paris Agreement.
Following, Challenging, or Shaping: Can Third Countries Influence EU Energy Policy?
Authors: Hofmann Benjamin , Jevnaker Torbjørg , Thaler Philipp
Published: March 2019

Can non-EU member states influence the EU’s energy policy? The Europeanization of energy policy in third countries is often described as a one-directional process in which these countries essentially adopt the EU energy acquis. Our article questions this dominant view by exploring whether and how third countries can influence the formulation and implementation of EU energy policy. We argue that relative differences in third country influence depend on their access to relevant venues and actors of EU policy-making as well as their structural power resources. We develop a typology linking these two factors to the outsider, follower, challenger, or shaper roles that third countries assume in EU energy governance. We empirically probe our argument in three case studies representing different models of EU–third country cooperation. Our cases include a group of nine Southeast and East European countries (Energy Community), Switzerland (bilateral arrangements), and Norway (European Economic Area). The analysis shows that it is access and structural power which together define the extent to which third countries are able to influence the formulation of EU energy policy and customize its implementation to their domestic needs. We find that while the Energy Community members are followers in EU energy governance, Switzerland and Norway are shapers. Strikingly, the influence of these two non-EU members may occasionally even surpass that of smaller EU member states. This highlights that third countries are not merely downloading EU energy regulation but sometimes also succeed in uploading their own preferences. Our contribution has implications for the post-Brexit EU–UK energy relations and qualifies claims about EU regulatory hegemony in the wider region.
QUALITY OF WATER IN THE MAIN CHANNEL OF THE KAKHOVKA IRRIGATION SYSTEM
Authors: Khokhlova L. , Lukashov D.
Published: March 2019

The physical-geographical and climatic conditions of the territories of the steppe zone of Ukraine, where the Kakhovka irrigation system is constructed, is considered. The role of the Kakhovka main channel in increasing the volumes of production of agricultural products in the steppe areas, intensification of all branches of agriculture and increasing the fertility of the land under irrigation conditions are determined. The volumes of water use for irrigation by agricultural producers during the vegetative period have been analyzed. The normative documents regulating the quality of water for irrigation by agronomic and environmental criteria are considered. The results of the analysis of the chemical composition of the water of the Kakhovka main channel within the limits of the Kherson and Zaporizhzhia oblasts, Kakhovsky reservoir, in the area of the location of the Main Pumping Station, for the period 2015-2017, are presented, an environmental assessment of the quality of water used for irrigation and drinking needs was conducted. Having analyzed the materials of scientific literature and annual reports of regional departments of ecology and natural resources, the main anthropogenic sources of pollution of hydro-amelioration objects have been identified. Provided recommendations for preventing the introduction of pollutants into reclamation facilities and improving the quality of water for irrigation and drinking purposes. The possible consequences of the action of pollutants on hydrobiocenoses and the aqueous medium as a whole are determined. Also established the role of hydrobiots in the processes of self-clearing of the water from pollutants.
The Early Neolithic Complex on the Tartas-1 Site: Results of the AMS Radiocarbon Dating
Authors: Molodin V. I. , Nenakhov D. A. , Mylnikova L. N. , Reinhold S. , Parkhomchuk E. V. , Kalinkin P. N. , Parkhomchuk V. V. , Rastigeev S. A.
Published: March 2019

AMS radiocarbon dating was applied to seven samples from Tartas-1, an Early Neolithic site in the Baraba forest-steppe, southwestern Siberia: four from pit 938, one from pit 990, and two from structure 6. Pits had been destined for fermenting fi sh, and contained offerings, such as corpses of animals (fox, hare, wolverine, dog), stone and bone artifacts, and fl at-bottomed clay vessels. On the basis of these fi nds, the Baraba culture was described. The results of the AMS radiocarbon analysis support the previous conclusion regarding the date of the complex — 7th millennium BC. A series of dates generated at the Curt Engelhorn Center for Archaeometry in Mannheim, Germany, for the Neolithic materials from Tartas-1 mostly fall within the 7th millennium, and the same applies to the dates relating to the Neolithic site of Vengerovo-2. The dates for structure 6 from Tartas-1 were generated at the Institute of Nuclear Physics SB RAS in Novosibirsk as well, agreeing with those from the Mannheim Center (for two samples, the results being virtually identical). In sum, the data obtained confi rm the correctness of dating the Early Neolithic complex from Tartas-1 to the 7th millennium BC. The Baraba culture is also dated to this time.
MECHANICAL CIRCULATORY SUPPORT IN PATIENTS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION
Authors: Grechishkin A. A. , Mayngart S. V. , Nekrasov A. S. , Fedorchenko A. N. , Porhanov V. A.
Published: March 2019

Despite the rapid evolution in the development of endovascular surgery, the mortality of patients undergoing percutaneous coronary interventions (PCI) with high risk of severe cardiac complications and critical conditions (cardiogenic shock, cardiac arrest) remains extremely high. The success of PCI directly depends on the ability of the Heart Team to prevent and timely eliminate severe cardiac disorders. Despite the rapid evolution in the development of endovascular surgery, the mortality of patients undergoing percutaneous coronary interventions (PCI) with high risk of severe cardiac complications and critical conditions (cardiogenic shock, cardiac arrest) remains extremely high. The success of PCI directly depends on the ability of the Heart Team to prevent and timely eliminate severe cardiac disorders. Pharmacological therapy is not able to completely resist the development of severe cardiac events during PCI. In such situations the usage of devices for percutaneous mechanical circulation support (PMCS) can make an invaluable help in the treatment of this group of patients. Despite the fact that the PMCS devices are used to stabilize patients with cardiogenic shock and to provide hemodynamic support for high-risk PCI for several decades, the results of their application remain ambiguous. The purpose of this article is to review all existing literature on modern PMCS devices, available data and research results, indications for their use, and operational considerations that can ensure the decision-making process in selecting optimal PMCS devices.
GENDER-RELATED DIFFERENCES AND TREATMENT FOR NON-ST SEGMENT ELEVATION ACUTE CORONARY SYNDROME IN A YOUNG WOMAN
Authors: Semukhina E. N. , Semukhin M. V. , Gapon L. I. , Zyryanov I. P.
Published: March 2019

Acute coronary syndrome in young women is of particular interest for today’s research. There are some data on the different effects of major risk factors among the sex groups, driven by the presence of specific risk factors in the female population. The clinical case reports different clinical course of atherosclerosis in men and women, presented with non-stenotic coronary atherosclerosis with hormonal imbalance and classical risk factors of complicated CAD.
12-MONTHS RESULTS OF LEFT MAIN STENTING IN PATIENTS WITH HIGH SYNTAX SCORES
Authors: Stolyarov D. P. , Sakhnov E. V. , Melnikov A. V. , Pligovka I. N. , Komarova E. V. , Tovbis E. M. , Sakovich V. A.
Published: March 2019

Aim. To compare the safety and efficacy of stenting of the left main coronary artery (LMCA) in patients with moderate to high risks estimated with the SYNTAX score.

Methods.112 patients with multivessel coronary disease and LMCA disease (SYNTAX score ≥23) and severe comorbidities were included in the study. All patients were deemed ineligible for CABG by the Heart Team. Patients were assigned to two groups according to the Syntax scores: Group 1 – patients with the SYNTAX scores of 23–32 (n = 66), and Group 2 patients with the SYNTAX scores of >32 (n = 46).

Results.107 patients completed the 12-months follow-up. 5 patients in Group 1 and 2 patients in Group 2 were lost to follow up. Myocardial infarction (MI) (8.06% versus 13.33%, p = 0.37757) and heart mortality (6.45% versus 6.67%, p = 0.9646) cumulative rates were similar within the 12-month follow-up. There were no strokes or noncardiac deaths in both groups. The 12-month confirmed rate of stent thrombosis in Groups 1 and 2 did not differ statistically (3.23% vs. 6.67%, p = 0.4051). The unadjusted model (effects of variables on survival) reported that age (OR 1.15 (95% CI 1.05– 1.26), p = 0.0032), pulmonary hypertension (OR 1.05 (95% CI 1.01–1.09), p = 0.0111) and mitral insufficiency (OR 2.65 (95% CI 1.13–6.21), p = 0.0252) affected the composite endpoint. The adjusted model determined that only age affected the prognosis (OR 1.17 (95% CI 1.05–1.29), p = 0.0038).

Conclusion.The first results of our study showed that stenting of LMCA in patients with moderate to high SYNTAX scores is a possible option and comparable with the 12-month follow-up. Age is as an independent predictor of future adverse events. Further evaluation of this complex patient cohort is required.
Immunohistochemical evaluation of Ki-67, Cyclin D1 and β-catenin expression in the subtypes of triple negative breast cancer
Authors: Vashchenko L N , Gudtskova T N , Nepomnyashchaya E M , Karnaukhov N S , Kvarchiya M V
Published: March 2019

Aim. To evaluate the expression levels of Ki-67 and cyclin D1 and β-catenin in the subtypes of triple negative breast cancer. Methods. The study was conducted on the surgical material from 60 patients of clinical stage 2A (T1N1M0 or T2N0M0) who were treated at the Rostov Research Institute of Oncology from 2012 to 2015. For immunohistochemistry, antibodies to estrogen and progesterone receptors, cytokeratins 5/6, Ki-67, cyclin D1, β-catenin, HER2/neu and EGFR proteins were used. Results. Triple negative breast cancer with the signs of basal epithelium was found to have a significantly higher expression level of Ki-67 compared to non-basal-like one. In some part of triple negative breast cancer samples overexpression of cyclin D1 was observed. The high level of cyclin D1 in the basal-like subtype was less common than in the subtypes without the signs of basal epithelium, but its average value was significantly higher. In triple negative cancer with cyclin D1 overexpression, the loss of β-catenin on the cell membrane and its abnormal accumulation in the cytoplasm was significantly more frequent. β-catenin translocation into the cell nucleus was observed only in basal-like triple negative cancer, and 2 times more often in case of cyclin D1 overexpression. Conclusion. In triple negative breast cancer tumors with overexpression of cyclin D1 and abnormal expression of β-catenin are observed in some cases; these biomarkers can be considered as potential therapeutic targets for this group of tumors.
L.L. Fofanof: 140th anniversary of his birth. Contribution to science
Authors: Abdulganieva D I , Kirillova E R , Bombina L K , Khusainova A K , Bol'shakov N A , Sabirova G Sh
Published: March 2019

The article is dedicated to Professor L.L. Fofanof’s scientific activity. He headed the faculty therapeutic clinic of Kazan Imperial University in 1915-1920. Being a student L.L. Fofanov was interested in pathological anatomy and physiology. His dissertation «To physiology of n. depressoris» was dedicated to studying the vasomotor center. During his visit in Germany he worked a lot. In Charite together with Professor His he studied gout and its treatment with Radium emanation. In Halle clinic under Professor Schmidt’s supervision he studied assimilation of starch in normal and pathological digestion. L.L. Fofanov also made a contribution to tuberculosis treatment: with professor V.F. Orlovskiy he studied treatment of tuberculosis with simulated pneumothorax. In his research professor L.L. Fofanov paid great attention to the issues of pathogenesis and pathogenetic substantiation of the clinical manifestation and treatment. During the World War I and Civil War he fought against typhus epidemies: he saw patients, gave lectures, studied the features of myocardial involvement. He died in 1920 from typhus.
Rãs: a mimesis de Dioniso
Authors: Carli Elisana De
Published: March 2019

A leitura das peças do comediógrafo Aristófanes (c.450-385 a.C.) permite identificar um assunto recorrente: o fazer teatral e seus elementos. Em Rãs representa-se uma viagem protagonizada por Dioniso, deus do teatro, preocupado com os ditames e os caminhos de sua arte e empenhado em resgatar a glória da tragédia. Para tanto, demarcada por duas fases no enredo e na estrutura da peça, o personagem encena seu caráter hibrido e as possibilidades de transformação que refletem elementos da composição teatral. A partir disso, focalizaremos, para este estudo, o modo de apresentação desse repertório, destacando a correlação entre a estrutura e o conteúdo deste texto teatral, salientando a composição estética do autor e da obra, através desse personagem que é o fio condutor e mote da peça, entendida como objeto estético, cênico e metateatral.
“Escrever é sangrar”: reflexões sobre ancestralidade, racismo e dor em Olhos d’água de Conceição Evaristo
Authors: Oliveira Natalino da Silva de
Published: March 2019

O objetivo deste artigo é analisar o conto Olhos d’água, de Conceição Evaristo, abordando questões de identidade, ancestralidade e racismo e suas relações com a situação do negro no Brasil. Além disso, visa demonstrar como se dá na narrativa citada a reflexão sobre a nacionalidade incompleta do negro brasileiro, partindo das noções de história e ideologia do progresso em Benjamin, de branqueamento e racismo em Fanon e de Estado de exceção em Agamben. Por meio da abordagem conjunta entre textos teóricos e texto literário, almeja-se seguir os rastros de uma formação de identidade, ainda que reconstruída e fragmentada. Afinal, seria possível construir a memória a partir de cacos, de escombros e a partir dela fortalecer valores identitários?
Apresentação
Authors: Dias André , Medeiros Elen de , Arbex Márcia , Alexandre Marcos Antônio
Published: March 2019

.
batalha de Eros no sertão de Rosa
Authors: Silva Claudicélio Rodrigues da
Published: March 2019

Resumo: O artigo se propõe a discutir a natureza erótica em Grande Sertão: Veredas estabelecendo como ponto de partida as noções de Eros apresentadas n’O banquete, de Platão. Sabendo-se que o discurso erótico no diálogo platônico é múltiplo, buscou-se neste estudo demonstrar que a natureza indômita de Eros agencia a narrativa de Rosa fundindo o plano da guerra exterior, as batalhas pelo poder no sertão, com o plano da guerra interior, o embate entre aquilo que a tradição expõe como interdito e o desejo que quer transgredir. Se Diadorim nutre o Eros que o impulsiona à guerra, Riobaldo é alimentado por um Eros que só pode consumar o desejado à luz da imaginação ou da pulsão de ver. O conceito freudiano de pulsão, ou impulso erótico, sustenta a tese de que a saga rosiana assume um caráter de prosa moderna justamente porque aciona categorias psicológicas no monólogo-diálogo de Riobaldo que permitem ao leitor confrontar o dentro e o fora, o eu e o outro, o narrado e o narrável. De natureza interdisciplinar, o estudo parte da filosofia de Platão e aproxima-se da psicanálise, com as categorias desenvolvidas por Freud (2010, 2013), tais como pulsão de vida e de morte e pulsão de olhar.Palavras-chave: Guimarães Rosa; erotismo; pulsão; desejo.Abstract: We propose a discussion about the erotic nature in Grande Sertão: Veredas (The Devil To Pay in the Backlands), establishing the Eros’ concept shown in Plato’s Συμπόσιον (Symposium) as the starting point. It is acknowledged that there’s a multiple erotic discourse in platonic dialogues, hence its study aims to show the Eros’ indomitable nature informs Rosa’s narrative. His narrative mixes the exterior war plan (the battles for power in northeast backlands) with the interior war plan (the clash between what the traditional society claim as a taboo and the desire to break free). If Diadorim nurtures the Eros connected to war impulses, Riobaldo is fed by an Eros that can only be consumed in the light of imagination or the drive to see. The Freudian concept of drive, or erotic impulse, sustains the thesis that Rosa’s journey emerges as a modern prose mostly because it fires psychological categories on Riobaldo’s monologue-dialogue, allowing the reader to confront the character’s inside out, the “me” and the “other,” the narrated and the tellable. This study develops its interdisciplinary nature as it starts from Plato’s philosophy and gets closer to psychoanalysis, with categories developed by Freud (2010, 2013), such as life drive versus death drive and sight drive.Keywords: Guimarães Rosa; erotism; drive; desire.
Anastasia e pervivência em João Guimarães Rosa
Authors: Marinho Marcelo , Silva David Lopes
Published: March 2019

Resumo: Este artigo parte de um pressuposto hipotético que jamais poderá se confirmar e menos ainda se infirmar, que jamais poderá se resolver ou se dissolver em toda sua plenitude, e por aí mesmo alcançará sua pervivência (na perspectiva do Fortleben benjaminiano) e imortalidade, por meio de múltiplas tentativas de interpretação-tradução. Trata-se de um koan protobiográfico legado por Guimarães Rosa a seus leitores, que abarca o conjunto de sua obra e alcança sua morte enigmática, previamente anunciada em vários de seus escritos e em múltiplas declarações sábia e parcimoniosamente lançadas ao vento por meio de eficazes passadores de vozes. Para explicitar os elementos desse koan, e com apoio no último e conclusivo verso lançado por Rosa (“as pessoas não morrem, ficam encantadas”), o conto “Conversa de bois” será percorrido em busca de eventuais pistas de convergência temática, que prenunciariam o desenredo de Grande sertão: veredas e a morte-ressurreição de Guimarães, ocorrida exatamente três dias após a posse na Academia Brasileira de Letras. Buscamos responder à seguinte questão, no que se refere à pervivência: o que se pode inferir das alterações incidentes entre a versão original do conto (constante em Sezão, 1937) e a efetivamente publicada em Sagarana (1946)?Palavras-chave: João Guimarães Rosa; “Conversa de bois”; pervivência; “autobiografia irracional”.Abstract: We lay upon a hypothetical assumption which could never be entirely solved neither denied, leading itself towards its own Fortleben (Walter Benjamin) and immortality, throughout multi-level layers of critical interpretation and translations. This is related to a proto-biographical koan, a Guimarães Rosa’s legacy to his readers, which covers his whole literary work and reaches his enigmatic death, previously announced within his writings and dissolved under multiple declarations blown into the wind through efficacious voice smugglers. Thus, the short story named “Conversa de Bois” will be crisscrossed in order to bring out some possible thematic convergent paths and clues. They would announce beforehand the final outcome of Grande sertão: veredas, as well as Rosa’s death-resurrection, precisely three days after his official entrance as a member into the Brazilian Academy of Literature. We aims to answer this question, related to Rosa’s planified Fortleben: what is possible to be inferred from the amendments introduced by the author into the different versions of Sagarana (1946)?Keywords: João Guimarães Rosa; “Conversa de bois”; Fortleben; “irrational autobiography”.
sertão de Bia Lessa
Authors: Baião Livia de Sá
Published: March 2019

Resumo: O objetivo do presente trabalho é refletir sobre a releitura dramática que a diretora Bia Lessa fez da obra Grande sertão: veredas, de João Guimarães Rosa. Com apoio de pressupostos teóricos de pensadores como Peter Brook, Bertold Brecht e Roland Barthes, a intenção é examinar a encenação do romance a partir do texto dramatúrgico (escrita cênica) construído pela própria diretora. Com vasta experiência em adaptações para o teatro de obras literárias canônicas (O homem sem qualidades, de Robert Musil; Os possessos, de Dostoievski; e muitas outras), Bia Lessa coloca em cena diferentes linguagens, tais como a expressão corporal trabalhada no limite e uma arquitetura cênica surpreendente. Assim, o sertão rosiano salta das páginas para o palco, eclodindo em pura teatralidade.Palavras-chave: Grande sertão: veredas, Bia Lessa, teatro, literatura, adaptação, encenação.Abstract: Our objective is to reflect on director Bia Lessa’s adaptation for the stage of Grande sertão: veredas novel. The main thinkers who will underpin this work are Peter Brook, Bertold Brecht and Roland Barthes. Our intention is to examine the dramatic text and the staging of the novel, both made by the director. With a vast experience in adapting canonic literary works (The man without qualities by Robert Musil; The possessed by Dostoievski, and many others), Bia Lessa takes books to theatre using different languages, such as body expression, explored to its limit and with an unusual set. Thus, Guimarães Rosa’s backlands is brought from pages to stage shining in pure theatricality.Keywords: The devil to pay in the backlands, Bia Lessa, theatre, literature, adaptation, staging.
Refazer estórico
Authors: Medeiros Rondinelly Gomes
Published: March 2019

Resumo: O artigo pretende evidenciar o protagonismo que as elaborações poético-ficcionais desempenham nas novelas “O recado do morro” e “Uma estória de amor”, de Corpo de baile. Descrevemos as ambivalências e os impasses próprios das consciências dos personagens protagonistas, Pedro Orósio e Manuelzão, e, em seguida, o confronto entre a angústia decorrente dos impasses e as irrupções e percursos das estórias, canções e poemas, bem como de seus lugares de origem e seus destinatários, como forma de compreender a incidência incontornável dessas elaborações poético-ficcionais sobre os desfechos das novelas.Palavras-chave: Guimarães Rosa; Corpo de baile; experiência literária; refazer estórico.Abstract: The article intends to highlight the protagonism played by poetic-fictional elaborations in the novels O Recado do Morro and Uma Estória de Amor, from Guimarães Rosa’s Corpo de Baile. We describe the ambivalences and impasses that characterises the protagonists' consciousness, Pedro Orósio and Manuelzão. Furthermore, we investigate the confrontation between the angst resulting from those dilemmas, and the stories’ paths, songs and poems; as well as their places of origin and their recipients, in order to understand the unavoidable incidence of these poetic-fictional elaborations on the novel conclusion.Keywords: Guimarães Rosa; Corpo de baile; literary experience; storical redoing.
SANTIAGO, Silviano. Genealogia da ferocidade: ensaio sobre Grande sertão: veredas, de Guimarães Rosa. Recife: Cepe, 2017.
Authors: Corpas Danielle
Published: March 2019

Resenha de SANTIAGO, Silviano. Genealogia da ferocidade: ensaio sobre Grande sertão: veredas, de Guimarães Rosa. Recife: Cepe, 2017.
Jensen and Ostrowski type inequalities for general Lebesgue integral with applications
Authors: Dragomir Sever
Published: March 2019

Some inequalities related to Jensen and Ostrowski inequalities for general Lebesgue integral are obtained. Applications for f-divergence measure are provided as well.
An empirical almost sure central limit theorem under the weak dependence assumptions and its application to copula processes
Authors: Dudziński Marcin
Published: March 2019

Let: \(\mathbf{Y=}\left( \mathbf{Y}_{i}\right)\), where \(\mathbf{Y}_{i}=\left( Y_{i,1},...,Y_{i,d}\right)\), \(i=1,2,\dots \), be a \(d\)-dimensional, identically distributed, stationary, centered process with uniform marginals and a joint cdf \(F\), and \(F_{n}\left( \mathbf{x}\right) :=\frac{1}{n}\sum_{i=1}^{n}\mathbb{I}\left(Y_{i,1}\leq x_{1},\dots ,Y_{i,d}\leq x_{d}\right)\) denote the corresponding empirical cdf. In our work, we prove the almost sure central limit theorem for an empirical process \(B_{n}=\sqrt{n}\left( F_{n}-F\right)\) under some weak dependence conditions due to Doukhan and Louhichi. Some application of the established result to copula processes is also presented.
Entire functions of exponential type not vanishing in the half-plane \(\Im z > k\), where \(k > 0\)
Authors: Hachani Mohamed Amine
Published: March 2019

Let \(P (z)\) be a polynomial of degree \(n\) having no zeros in \(|z| < k\), \(k \leq 1\), and let \(Q (z) := z^n \overline{P (1/{\overline {z}})}\). It was shown by Govil that if \(\max_{|z| = 1} |P^\prime (z)|\) and \(\max_{|z| = 1} |Q^\prime (z)|\) are attained at the same point of the unit circle \(|z| = 1\), then \[\max_{|z| = 1} |P'(z)| \leq \frac{n}{1 + k^n} \max_{|z| = 1} |P(z)|.\]
The main result of the present article is a generalization of Govil's polynomial inequality to a class of entire functions of exponential type.
A spatial individual-based contact model with age structure
Authors: Jasińska Dominika
Published: March 2019

The Markov dynamics of an infinite continuum birth-and-death system of point particles with age is studied. Each particle is characterized by its location \(x\in \mathbb{R}^d\) and age \(a_x\geq 0\). The birth and death rates of a particle are age dependent. The states of the system are described in terms of probability measures on the corresponding configuration space. The exact solution of the  evolution equation for the correlation functions of first and second orders is found.
On almost complex structures from classical linear connections
Authors: Kurek Jan , Mikulski Włodzimierz M.
Published: March 2019

Let \(\mathcal{M} f_m\) be the category of \(m\)-dimensional manifolds and local diffeomorphisms and  let \(T\) be the tangent functor on \(\mathcal{M} f_m\). Let \(\mathcal{V}\) be the category of real vector spaces and linear maps and let \(\mathcal{V}_m\) be the category of \(m\)-dimensional real vector spaces and linear isomorphisms. We characterize all regular covariant functors \(F:\mathcal{V}_m\to\mathcal{V}\) admitting \(\mathcal{M} f_m\)-natural operators \(\tilde J\) transforming classical linear connections \(\nabla\) on \(m\)-dimensional manifolds \(M\) into almost complex structures \(\tilde J(\nabla)\) on \(F(T)M=\bigcup_{x\in M}F(T_xM)\).
The natural operators of general affine connections into general affine connections
Authors: Kurek Jan , Mikulski Włodzimierz M.
Published: March 2019

We reduce the problem of describing all \(\mathcal{M} f_m\)-natural operators  transforming general affine connections on \(m\)-manifolds into general affine ones to the known description of all \(GL(\mathbf{R}^m)\)-invariant maps \(\mathbf{R}^{m*}\otimes \mathbf{R}^m\to \otimes^k\mathbf{R}^{m*}\otimes\otimes ^k\mathbf{R}^m\) for \(k=1,3\).
On branchwise commutative pseudo-BCH algebras
Authors: Walendziak Andrzej
Published: March 2019

Basic properties of branches of pseudo-BCH algebras are described. Next, the concept of a branchwise commutative pseudo-BCH algebra is introduced. Some conditions equivalent to branchwise commutativity are given. It is proved that every branchwise commutative pseudo-BCH algebra is a pseudo-BCI algebra.
Determination of surface free energy components of organic liquids by the thin layer wicking method
Authors: Hołysz Lucyna , Szcześ Aleksandra
Published: March 2019

Using the layer wicking method (TLW method) the electron-donor interactions of surface free energy of the organic liquids: benzene (C6H6), toluene C6H5CH3), and tetrahydrofuran ((CH2)4O) was determined. For this purpose the penetration rate measurements of these liquids in the porous layers of silica gel and alumina were performed. The obtained values of the electron-donor parameter of surface free energy of the studied organic liquids were compared with the literature data obtained by the direct measurement of the interface tensions of water/organic liquids.
Synthesis and characterization of mesoporous silica: laboratory exercises for students
Authors: Kosmulski Marek , Mączka Edward
Published: March 2019

Synthesis and characterization of SBA-15 were proposed as a laboratory course: linked series of exercises for graduate students. The standard preparation method was modified to fit a typical schedule of students’ classes, that is, 3-hours units every second week. The properties of materials obtained by different students’ groups were compared with the properties of materials obtained by means of a standard method.
Study of the influence of the binary mixtures of fluorocarbon surfactants on the surface tension of water
Authors: Taraba Anna , Szymczyk Katarzyna
Published: March 2019

Influence of the binary mixtures of fluorocarbon surfactants Zonyl FSO-100  (FSO100) and Zonyl FSN-100 (FSN100) on the surface tension of the water was studied. The effectiveness of adsorption process of the surfactant at the water-air interface was calculated from the obtained values of the surface tension of studied mixtures. Also the maximum surface area per molecule of surfactant in the interfacial area  and the free energy at the water-air interface  were determined. Moreover, the existence of synergetizm or antagonism effect, which reduces the surface tension of the water was examined. On the basis of the Rosen's model parameter the values of intermolecular interactions in the mixed monolayer adsorption were calculated.
Synthesis of diphenylphosphinic acid esters
Authors: Korzeniowska Ewelina
Published: March 2019

The development of new methods for the synthesis of organophosphorus compounds is still an important part of organic chemistry due to the high demand for these compounds in organic synthesis as well as in asymmetric catalysis. Most of the methods for the synthesis of these compounds include the reactivity of the phosphorus atom, which depending on the structure might exhibit both electrophilic and nucleophilic properties. Herein, I will present the results concerning synthesis of diphenylphosphinic acid esters.