bluuebunny/crossref_metadata_2025 huggingface dataset:
INVESTMENT ACTIVITIES AS THE BASIS OF SOCIO-ECONOMIC TRANSFORMATIONS IN THE AGRICULTURAL INDUSTRY
Authors:   Vinnytsia National Agrarian University, Hryshchuk Nadiia
Published: April 2022

The article examines the relevance of investment as an external source of financing for agricultural producers. The views of scientists on the problems of investment support of the agricultural sector of the economy, their significant contribution to the creation and development of theory and practice of investment progress of small and medium-sized agribusinesses. It is noted that financial security in the form of attracting and developing investments is one of the most important factors influencing the efficiency of agricultural enterprises. Using the analysis of investment support of the agricultural sector, their role as an important source of financial support for the functioning of agricultural enterprises is revealed. An analysis of the investment climate of Vinnytsia region and based on which it is proved that investment resources in combination with a well-formed investment development plan can create economic development in medium-sized enterprises in the agricultural sector and the economy. Foreign investment plays an important role in assessing the investment climate in Ukraine's agro-industrial complex. It was outlined that rapid attraction and optimal use of investments is the fastest way to raise the economic development of the state to a new level, including investment of effective instruments provides innovative development of agricultural enterprises. Emphasis is placed on the problems that hinder the development of the agricultural sector, the state of financial security of agricultural producers, and hence the regulation of investments of agricultural enterprises. It is proved that compliance with state guarantees for the protection of foreign investment will help ensure a favorable investment climate. Stable conditions for foreigners' investment activities, observance of their legal rights and interests, and full preservation of foreign investments are guaranteed. It is determined that the introduction of effective investment instruments and their further application will ensure the innovative development of agricultural enterprises.
THEORETICAL AND METHODOLOGICAL GROUNDS OF IDENTIFICATION OF INTERNAL FACTORS OF THE FUNDAMENTAL AND STAKEHOLDER VALUE ADDED OF ENTERPRISES
Authors:   V.N. Karazin Kharkiv National University, Davydov Oleksandr
Published: April 2022

In the article it is researched the development of theoretical and methodological grounds of identification of internal factors of the fundamental and stakeholder value added of enterprises in the process of implementing the system of value-based management at the microeconomic level on the basis of the factor approach. The fundamental and stakeholder value added of enterprises is considered as the factor system, the elements of which are its internal factors. The problem of substantiation of the type of a factor model for studying the dependence of the fundamental and stakeholder value added of enterprises on its internal factors has been researched. A structural and logical model for calculating the fundamental and stakeholder value added of enterprises as a multifactorial phenomenon has been developed. The indicators that are directly involved in calculation of the fundamental and stakeholder value added of enterprises have been studied. It is revealed the connection with the scope of internal and external factors of those indicators which are directly involved in the calculation of the fundamental and stakeholder value added of enterprises. There was substantiated the necessity of building a stochastic factor model for the formalized determination of the mathematical dependence of the fundamental and stakeholder value added of enterprises on its internal factors. It is determined the expediency of applying the correlation and regression method in the process of stochastic modeling of the factor system, in which internal factors and the fundamental and stakeholder value added of enterprises are united by one cause- and-effect relationship. There has been studied the problem of identification of those internal factors which have the most probable influence on the fundamental and stakeholder value added of enterprises in econometric modeling using the correlation and regression method. It is revealed the content of transformation of factor indicators while building a multiple regression model to study the dependence of the fundamental and stakeholder value added of enterprises on its internal factors. In the process of correlation and regression modeling the internal factors of the fundamental and stakeholder value added and their indicators are determined.
FEATURES OF ADVERTISING IN TOURISM AND HOTEL AND RESTAURANT BUSINESS
Authors:   Volodymyr Dahl East Ukrainian National University, Zavarika Halyna
Published: April 2022

The article discusses the features of tourist and hotel and restaurant advertising. It is noted that marketing in the tourism industry should perform three main functions: ensuring the effective functioning of enterprises in the tourist market; regulating tourist demand, prices, advertising activities; forming new needs of tourists, motivating them to visit existing tourist institutions. With effective advertising activities, all the declared functions will be performed, which is proven by foreign enterprises. It is established that at the level of integration, the activity of promoting a tourist product is based on orientation to the consumer and his requests; the formation of a brand strategy and the promotion of branding philosophy as the basis for a set of Marketing Communications; the implementation of Marketing Research in practice; attention to service programs; a balanced approach to product promotion using the entire set of Marketing Communications; the creation of integrated databases; attention to personal sales and personalities of sellers. Information and advertising level is provided on the Internet, on the company's websites, which describe the tourist products of the company with an emphasis on the uniqueness of the products, as well as in places of sale of tours. Advertising in tourism should be more creative, moving from simple information to argumentation or applying the image principle. It is at this stage that it is advisable to use PR technologies, and consumers will test Sales promotion technologies. Positioning focuses on the features of the company and product, such a position in the minds of customers makes it possible to reduce advertising costs in the future, it is easier to acquire a high level of loyalty and, as a result, maintain a high level of competitiveness. An important method is to organize study trips for employees. So, allowing managers to evaluate the safety of the trip and high-class service, as well as personally see all the resorts offered, the agency together with the operator creates a professional staff of managers. Agents will be more likely to recommend resorts that they have visited and evaluated perfectly on their own experience.
STATE FINANCIAL SUPPORT IN THE SYSTEM OF FINANCIAL SECURITY FOR THE FARMS IN UKRAINE
Authors:   Sumy National Agrarian University, Maslak Nataliia , Maslak Oleksandr ,   Sumy National Agrarian University
Published: April 2022

The article establishes the specifics of the activities of farms as one of the forms of management in the agricultural sector of the economy. It has been determined that the main forms of financial support for farms are budget financing, lending and self-financing. The issues of finding the optimal combination of various sources of financial support and determining the effectiveness of state financial support are relevant and need to be addressed. The role of state financial support, as well as its place in the system of financial support for the activities of farms, are defined in the article. The types and directions of state financial support for farms in Ukraine, as well as existing financial support programs, were studied. The analysis of the volume of state financial support for farms for the period 2018-2021 was carried out and the impact on the dynamics of development of farms of various types was determined. The main problems of obtaining and using state financial support are identified. The necessity of taking into account indicators of the effectiveness of the use of funds and achieving the established goals of providing state support funds when making a decision on the formation of support programs and mechanisms for distributing funds is substantiated. State financial support for farms is carried out by stimulating the increase in the volume of agricultural products with high added value; development of existing credit and financial mechanisms and introduction of new financial instruments; creation of favorable conditions for effective activity; involvement of youth in agriculture. The article substantiates that the main areas of state financial support for farms in Ukraine are: encouraging the creation of new farms and strengthening the competitiveness of existing farms; stimulating the development of agricultural service cooperatives; stimulating the transition of farms to the creation of organic products (raw materials); stimulation of primary processing and processing of products grown by farms; support for the development of animal husbandry in farms; technical and technological renewal of farms and agricultural cooperatives.
CONTROL OVER ACCOUNTING OF COMMODITY OPERATIONS OF PHARMACEUTICAL INDUSTRY TRADE ENTERPRISES AND POSSIBLE WAYS OF ITS IMPROVEMENT
Authors:   Vinnytsia Institute of Trade and Economics of Kyiv National University of Trade and Economics, Datsenko Ganna , Kydurko Olena ,   Vinnytsia Institute of Trade and Economics of Kyiv National University of Trade and Economics
Published: April 2022

This article discusses the peculiarities of the organization of control over the accounting of commodity transactions of enterprises operating in the field of trade. The article also provides a system and basic methods used in the control of accounting for commodity transactions in the pharmaceutical industry. The development of the pharmaceutical industry as a system is impossible without such an integral part of it as trade, which is an active participant in the pharmaceutical market and a link between manufacturers and consumers of medicines. In modern economic conditions, the pharmaceutical industry is characterized by increasing complexity of the structure due to the expansion of activities, the growth of pharmaceutical products circulating through its channels, increasing the number of structural elements and the diversity of their relationships. In difficult conditions of functioning of pharmacy one of the most important directions of increase of efficiency of its activity becomes improvement of management of commodity operations. That is, accounting, control and analysis of commodity transactions in the trade are management functions that collect information, ensure its accuracy and reliability, confirm data and submit them in a form convenient and necessary for use in the implementation of management functions and decisions on development directions enterprises. Therefore, pharmaceutical companies must monitor inventories, most of which are medicines, as there is a risk of incorrect accounting, quality determination, storage conditions and more. It should be noted that the pandemic of coronavirus disease COVID-19 is prevalent in the world, due to the quarantine measures taken, the authorities are creating new laws that need to study the situation, change and introduce new rules and methods of accounting for pharmaceutical. That is, today this branch of trade enterprises is very important and needs special attention to the accounting of goods and control over it. Given the above, possible ways to address issues and improve the control of commodity transactions were proposed in order to establish the effectiveness and soundness of the inventory management system.
THE CONGLOMERATION OF INTERNATIONAL TOURIST ROUTES FROM THE COUNTRIES OF THE BLACK SEA BASIN TO UKRAINE BY THE EXAMPLE OF THE FORMATION OF NEW WINE TOURS
Authors:   Odesa National Academy of Food Technologies, Liganenko Margaryta
Published: April 2022

The article examines and analyzes the tourist potential of the Black Sea basin countries, as well as natural conditions and resources, the quality of infrastructure of the countries, tourist services. The research of the article is to form a portrait of a potential tourist and wine routes of the Black Sea basin countries that have been studied. There are consumer segments that can be chosen as targets for promotion of wine tours for travel agencies and wine companies. It can be argued that with active information support, wine tourism can gain wide popularity in the south of Ukraine and attract more foreign tourists to this part of the country. Based on the obtained results the conclusions about the level of tourist potential, as well as the relevance and practical value of creating wine tours in the countries of the Black Sea basin are formulated. The results can be used in practice in creating wine tours in other tourist destinations, in the promotion of tourist products, as well as in creating tours to the countries of the Black Sea basin.
Para administrar lo invisible. Hacia un modelo de gestión del conocimiento para la MIPYME
Authors: Ramírez Solís Edgar Rogelio
Published: April 2022

n este artículo se presenta un modelo sistemático de gestión del conocimiento, diseñado desde y para la pequeña y mediana empresa. Se discuten los elementos más importantes de este modelo y se presenta su aplicación práctica en una pequeña empresa del sector calzado en Guadalajara, Jalisco.
¿Del Fordismo a la Acumulación Flexible?
Authors: Bellon Álvarez Luis Alberto
Published: April 2022

El presente trabajo tiene como objetivo fundamental identificar las características del fordismo, así como los sistemas de producción flexibles situándolos dentro de las nuevas realidades sociales y económicas de la actual economía globalizada. De este modo se busca estudiar la transición del taylorismo al fordismo, haciendo una reflexión sobre el contexto y la relación que se tiene con los cambios industriales y organizacionales sucedidos desde la década de los años sesenta, que desencadenaron en la crisis del fordismo y la aparición de los modelos de acumulación flexibles
La optimización del flujo de efectivo utilizando el modelo Miller-Orr: evidencia empírica
Authors: Bonales Valencia Joel , Muñoz Bandala Jesús
Published: April 2022

El objetivo de este artículo es presentar los resultados de la optimización del flujo defectivo, para cumplir las obligaciones inmediatas de Banco de México-fiRa, al aplicar el modelo Miller-orr. El artículo tiene cuatro apartados: primero, analiza los alcances y limitaciones que se obtuvieron en la investigación del 1 de noviembre de 2005 al 1 de julio de 2006 de julio; la segunda parte discute la formación, la integración y el funcionamiento de Banco de México-fiRa; la tercera se refiere a las características principales del modelo Miller-orr; y la última parte determina el flujo de efectivo óptimo.
El entorno económico e institucional de aliento a la inversión y la competitividad en México
Authors: Pineda Ortega Pablo
Published: April 2022

El objetivo del ensayo es analizar las condicionantes que contribuyen a generar un mejor entorno para la competitividad de las empresas, revisándolas con referencia al caso mexicano. De este modo, después de presentar el contexto económico global se analizan las dos temáticas generales de especial relevancia sobre las políticas públicas promotoras de la competitividad: la de las precondiciones básicas para aplicarla, y la de los instrumentos para su promoción. La metodología consistió en delimitar los ámbitos de las políticas públicas relevantes para la competitividad, a partir de lo cual se recabó la información empírica para el caso mexicano. Los resultados permiten concluir que el avance mexicano es parcial y que quedan importantes tareas pendientes.
La gestión de las redes sociales del conocimiento para el desarrollo de la investigación y docencia
Authors: Gómez Ortíz Rosa Amalia , López Miranda Montserrat América
Published: April 2022

Se subraya la importancia de la gestión para establecer una red social de conocimiento para el desarrollo de la investigación y la docencia; por ello se propone un modelo de gestión que involucra como base la red de comunicación telemática. Se revisan diferentes posturas teóricas sobre los términos de red telemática, red social, sus implicaciones y dinámicas, así como los aspectos que intervienen en la gestión. Se resaltan elementos puntuales que habrán de tomarse en cuenta para implementar una red de investigación y docencia en los ámbitos local, regional e internacional.
La Problemática de la Conservación de los Recursos como Expresión Próxima del fin Último de la Perpetuidad del Poder en el Siglo XVII (Huancavelica, Perú, 1597-1645)
Authors: Pardo Jorge Alejandro Laris
Published: April 2022

El propósito de este artículo es exponer en qué contexto semántico y con que propósito se usó el concepto “conservación” por los funcionarios de la Corona española en la minería americana de mercurio al comenzar el siglo XVII.  El problema de la conservación de la salud de los trabajadores y los recursos naturales no es algo exclusivo de los últimos tres siglos. Se ha manifestado de manera distinta en diversos tiempos de acuerdo a los intereses e idiosincrasias del momento. En Occidente, estas preocupaciones tienen profundas raíces históricas. Con el fin de contribuir a su conocimiento, se ha dividido este trabajo en tres apartados, en el primero se presenta el contexto histórico de la mina de Huancavelica al comenzar el siglo XVII, el segundo continua esta exposición con un breve recorrido por la historia del Hospital Real de Huancavelica. Finalmente, en el tercer apartado se aborda de lleno el propósito que es demostrar que para la Corona, la conservación tenía un sentido eminentemente político, ligado a la perpetuidad de su poder en la zona.
Interdisciplinaridade em Ciências Ambientais: Monitoramento Ambiental na Prevenção de Futuras Pandemias
Authors: Schmitt Jairo Lizandro , Rocha Crístian Yan Montana Crístian Yan Montana da , Galvincio Josiclêda Domiciano , Almeida Jarcilene Silva
Published: April 2022

Este artigo apresenta uma análise sobre a interdisciplinaridade em Ciências Ambientais, com o foco na prevenção de futuras pandemias. Também discutimos sobre grandes crises sanitárias e humanitárias da história e suas relações com o ambiente. A pesquisa realizada foi de caráter descritivo e exploratório e buscou na literatura subsídios para discutir e refletir sobre a tríade ser humano, pandemia e ambiente. Considerando a relação dinâmica entre o ser humano e o ambiente, destacamos que por meio de um diálogo interdisciplinar, entre atores pertencentes às ciências exatas, biológicas, sociais e humanas, podem ser propostas ações mais efetivas para alcançarmos um Planeta mais sustentável no futuro. Dentre os diferentes caminhos encontrados, propomos a ferramenta de monitoramento ambiental para observar, conhecer, inferir e investigar sobre desafios de saúde pública, com especial atenção à prevenção de epidemias e pandemias.
La Huella Humana en la Isla Robinson Crusoe (Archipiélago de Juan Fernández) entre los Siglos XVI y los Albores del Siglo XVII: Una Impronta para el Futuro
Authors: Espinoza Fernando Venegas , Francioli Sergio Elórtegui
Published: April 2022

En este artículo se profundiza el impacto de la huella humana en el Archipiélago de Juan Fernández, y particularmente en la isla Robinson Crusoe (Santa Cecilia), entre 1574 y principios del siglo XVII. Se analizan las fases de ocupación temprana con las implicancias de la introducción de ganado caprino (Capra hircus), los inicios de la explotación comercial de la pesquería y el lobo marino (Arctocephalus philippii), y la tala del bosque fernandeziano (myrtisylva fernandeziana) con “indios hacheros”, que alcanzó dimensiones catastróficas, según se denuncia en un juicio que levantó la Orden de Jesús, propietaria de 500 cuadras en Robinson Crusoe. En el proceso se afirma que si se seguía talando, la isla quedaría desierta, lo que se convertiría en una premonición de lo que ocurriría en el futuro con vastos territorios isleños. En términos metodológicos, la investigación descansa en la revisión de fuentes primarias (escritos de Diego Rosales y fondo Real Audiencia), fuentes secundarias secundarias (estudios históricos, ambientales y de las ciencias naturales) y en el trabajo de campo interdisciplinario.
Severe Anemia and Six-Month All-Cause Mortality in Chronic Kidney Disease Patients Undergoing Hemodialysis
Authors: Perdhana Langgeng , Chasani Shofa
Published: April 2022

Anemia is often found in patients with Chronic Kidney Diseases (CKD). Anemia can affect poor outcomes in hemodialysis patients. However, no publications examined the role of severe anemia as a predictor factor in six-month all-cause mortality in hemodialysis patients. Therefore, further study was needed to answer these questions. This study aimed to determine the role of severe anemia and six-month all-cause mortality in hemodialysis patients. The cohort design study was carried out from October 2019 to March 2020 at the Hemodialysis Unit of Roemani Muhammadiyah Hospital Semarang. The dependent variable was severe anemia, defined as hemoglobin levels <8.0 g/dL. The mortality rate was investigated over six months after the baseline measurements. Among 85 respondents, 35 (41.2%) respondents were categorized into severe anemia, and 50 (58.8%) respondents were categorized into non-severe anemia groups. The respondents consisted of 54 (63.5%) males and 31 (36.5%) females. The hemoglobin level in the severe and non-severe anemia groups was 7.2 ± 0.6 and 9.5 ± 1.2 (mean ± standard deviation). The Kaplan Meier survival curve showed that the non-severe anemia group had a higher survival rate than the severe anemia group (98.0% vs. 82.9%, p = 0.011). The Cox regression analysis found a significant relationship between anemia severity and 6-month all-cause mortality in hemodialysis patients (p = 0.027; Hazard ratio: 9.3). Severe anemia plays a role as a predictor factor in six-month all-cause mortality among hemodialysis patients.
الوزير نظام الملك الطوسي وثورة التعليم السُّني لتعزيز الأمن الفكري الإسلامي في القرن الخامس الهجري
Authors: Seggani Souheila
Published: April 2022

This research deals with the Seljuk Minister Nizam al-Mulk al-Tusi and his efforts in protecting Islamic intellectual security and facing its challenges by addressing the establishment of Nizamiyyah schools (regular schools), as a renaissance project with the purpose to face the most prominent challenges that threatened Islamic intellectual security in the fifth century (Hijra), represented by the Shi‘ite tide and the phenomenon of religious extremism. The problem statement of this research is that intellectual security is currently threatened by religious extremism, and that it is trying to identify ways to confront it and the means that contribute to the strengthening and realization of Islamic intellectual security. The importance of the study lies in demonstrating the role of educational institutions in establishing the correct Islamic faith and reducing the spread of the phenomenon of intolerance and intellectual and religious extremism in the modern times. This research used both the descriptive historical and analytical approaches. The results of this research show that the main goal for which the Nizamiyyah schools were established is to revive the role of the Sunnah in the life of the Ummah by eliminating Shi‘ite ideas and reducing their influence and also opposing all deviant sects by promoting and renewing the scientific movement in accordance with the reality of the Islamic religion and its moderation.
يتناول هذا البحث الحديث عن الوزير السلجوقي نظام الملك الطوسي وجهوده في حماية الأمن الفكري الإسلامي ومواجهة تحدياته من خلال التطرق إلى تأسيس المدارس النظامية كونها مشروع نهضوي يواجه باستراتيجيته وأهدافه أبرز التحديات التي هددت الأمن الفكري الإسلامي في القرن الخامس الهجري متمثلة في المد الشيعي وظاهرة التطرف الديني. ويهدف هذا البحث إلى بيان دور المؤسسات التعليمية والتربوية في ترسيخ العقيدة الإسلامية الصحيحة والحد من انتشار ظاهرتي التعصب والتطرف الفكري والديني دعما للأمن الفكري في القرن الخامس الهجري. استخدمت الباحثة المنهج التاريخي الوصفي حيث تضمن بيان الظروف الدينية والفكرية والأسباب التي دعت إلى تأسيس المدارس النظامية، وكذا المنهج التحليلي في توضيح الرؤى الفكرية والمذهبية التي أنيطت بتلك المدارس. وتظهر نتائج هذا البحث أن الهدف الأساسي من إنشاء المدارس النظامية هو تحقيق أمن فكري إسلامي من خلال إحياء دور السنة في حياة الأمة بالقضاء على الأفكار الشيعية والعمل على تقليص نفوذها ومناهضة كل الفرق المبتدعة من خلال النهوض بالحركة العلمية وتجديدها بما يتوافق مع حقيقة الدين الإسلامي ووسطيته.
Cendekiawan Heresiografi Awal dalam Perbandingan Agama: Muhammad ‘Abd Al-Karim Al-Shahrastani dan Kitabnya, Al-Milal Wa Al-Nihal
Authors: Sabjan Muhammad Azizan
Published: April 2022

This study is an effort to highlight the views of one of the Islamic scholars who has contributed a lot of time and energy to studying the traditions of other religions. His name was Abū al-Fath Muhammad Ibn ‘Abdul al-Karīm Ahmad al-Shahrastānī (479/1086-548/1153). Thus, the study presented here is to look at the typological nature of religion as it has been developed exclusively by al-Shahrastānī. The focus of the writing is on how he classifies religious typologies and how he expresses and elaborates on such classifications in his masterpiece, al-Milal wa al-Nihal. This research employs a qualitative method by analyzing data descriptively. The finding of study found that the question of religious recognition and respect, as well as tolerance, can be observed from the concept of religious typology as established by al-Shahrastānī in his book, al-Milal wa al-Nihal.
ABSTRAK
Kajian ini merupakan satu usaha bagi mengetengahkan pandangan salah seorang cendekiawan Islam yang telah banyak memberikan sumbangan masa dan tenaga dalam mengkaji tradisi agama lain.  Nama beliau adalah Abū al-Fath Muhammad Ibn ‘Abdul al-Karīm Ahmad al-Shahrastānī (479/1086-548/1153). Justeru, kajian yang dibentangkan ini adalah untuk melihat sifat tipologi agama seperti yang telah dibangunkan secara eksklusif oleh al-Shahrastānī. Fokus penulisan tertumpu kepada bagaimana beliau mengklasifikasikan tipologi agama dan bagaimana beliau menyatakan serta menghuraikan pengklasifikasian tersebut dalam karya agungnya, al-Milal wa al-Nihal. Diharapkan kajian ini dapat memberikan pemahaman dan pengkayaan wacana tentang konsep tipologi agama seperti yang telah dibentuk oleh al-Shahrastānī dalam kitabnya, al-Milal wa al-Nihal.
Characterization of Eye Signals in The Noble Prophetic Hadith
Authors: Hussein Abdullah Daad Younis , Ab. Halim Zulazhan , Abdul Hamid Mohd Fauzi
Published: April 2022

Eye gestures are an important component in the expression of meaning and sign. It is considered one of the most active types of signals and is an expressive language that allows communication to take place more meaningfully. For the ancient Arabs, paying attention to the eyes when communicating and expressing was considered important, which tacitly made them agree on the importance of the eyes in the process of expressing one’s thoughts. This paper aims to reveal the importance of eye gestures that are visible in the facial expressions of the Prophet Muhammad PBUH. Accordingly, the methodology employed is through a qualitative approach using content analysis involving the hadith narrations regarding the eye signals of the Prophet PBUH and the scholars' descriptions of them. The findings of the study showed that eye signals were visible in the facial expressions of the Prophet PBUH which were acceptable to the Arabs and by the psychological state of the recipient. It can be concluded that non-verbal communication was once used by the Prophet PBUH and this study suggests that future conducted studies can link between the practices of the Prophet PBUH and the non-verbal practices of modern society today.
Tahap Ketepatan Sebutan Konsonan Arab Sukar oleh Murid Prasekolah dalam Pembacaan Al-Quran
Authors: Hussin Mohamad , Mat Nuar Ain Zuhaili
Published: April 2022

This study aimed to identify the pronunciation of Arabic consonants in difficult categories by preschool students and analyze the forms of errors made. This study is a qualitative study that uses the method of audio recording of readings and review of pronunciation accuracy by experts in the field to obtain the required data. The results showed that there were various pronunciation errors from the aspect of articulation points and the qualities of the letters. Ten Arabic consonants have changed to other consonant in terms of articulation with different frequencies. Consonant sounds in the students’ mother tongue are more dominant in their pronunciation triggering the errors. Therefore, efforts to train students in the correct pronunciation of Arabic consonants are necessary to produce correct consonant pronunciation.
ABSTRAK
Kajian ini bertujuan untuk mengenal pasti sebutan konsonan Arab dalam kategori sukar oleh murid prasekolah dan menganalisis bentuk kesilapan yang dilakukan. Kajian ini merupakan kajian kualitatif yang menggunakan kaedah rakaman audio pembacaan dan semakan ketepatan penyebutan oleh pakar bidang bagi memperoleh data yang diperlukan. Hasil kajian menunjukkan berlaku pelbagai kesilapan penyebutan dari aspek makhraj dan sifat huruf. Sepuluh konsonan Arab telah ditukar bunyinya kepada bunyi konsonan lain dengan kekerapan yang berbeza. Bunyi konsonan bahasa ibunda murid lebih mendominasi sebutan mereka menyebabkan kesalahan berlaku. Oleh yang demikian usaha melatih murid cara sebutan konsonan Arab yang betul adalah diperlukan untuk menghasilkan sebutan konsonan yang tepat.
The Approach of Reality Therapy in Solving Foreign Student’s Crisis
Authors: Abdul Aziz Abdul Rashid , Mohd Yusof Siti Nubailah , Mohamad Nor Azmawaty
Published: April 2022

The crisis faced by foreign students need to be addressed to ensure that the goal of completing their study is achieved successfully. Financial issue has been identified as the main problem. Hence, this study was done to explore major issues faced by foreign students throughout their life in campus. This is a qualitative study using interview sessions as a study design. The subject in this study is a 21 year-old Indonesian student who faced stress and loss of concentration in her study due to financial problem. This study revealed that the financial issue is the common theme experienced by the respondent. This is due to the relevancy that money is one of the most important things to survive in life, and it has become a ‘mediator’ for resources toward basic needs in life. Reality therapy and in particular the techniques of WDEP and SAMIC was employed in the counselling session to help deal with the respondent’s issues. Indeed, this study highlighted the success of using Reality Therapy to help the respondent in making sound decisions to solve issues faced. It was also noted that the therapist plays an active role in helping the respondent to be aware and responsible in solving her issues.
Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas
Authors: Lopez Cristina , Schleussner Nikolai , Bernhart Stephan H. , Kleinheinz Kortine , Sungalee Stephanie , Sczakiel Henrike L. , Kretzmer Helene , Toprak Umut H. , Glaser Selina , Wagener Rabea , Ammerpohl Ole , Bens Susanne , Giefing Maciej , Sanchez Juan C. Gonzalez , Apic Gordana , Hubschmann Daniel , Janz Martin , Kreuz Markus , Mottok Anja , Muller Judith M. , Seufert Julian , Hoffmann Steve , Korbel Jan O. , Russell Robert B. , Schule Roland , Trumper Lorenz , Klapper Wolfram , Radlwimmer Bernhard , Lichter Peter , Kuppers Ralf , Schlesner Matthias , Mathas Stephan , Siebert Reiner
Published: April 2022

Histone methylation-modifiers, such as EZH2 and KMT2D, are recurrently altered in B-cell lymphomas. To comprehensively describe the landscape of alterations affecting genes encoding histone methylation-modifiers in lymphomagenesis we investigated whole genome and transcriptome data of 186 mature B-cell lymphomas sequenced in the ICGC MMML-Seq project. Besides confirming common alterations of KMT2D (47% of cases), EZH2 (17%), SETD1B (5%), PRDM9 (4%), KMT2C (4%), and SETD2 (4%), also identified by prior exome or RNA-sequencing studies, we here found recurrent alterations to KDM4C in chromosome 9p24, encoding a histone demethylase. Focal structural variation was the main mechanism of KDM4C alterations, and was independent from 9p24 amplification. We also identified KDM4C alterations in lymphoma cell lines including a focal homozygous deletion in a classical Hodgkin lymphoma cell line. By integrating RNA-sequencing and genome sequencing data we predict that KDM4C structural variants result in loss-offunction. By functional reconstitution studies in cell lines, we provide evidence that KDM4C can act as a tumor suppressor. Thus, we show that identification of structural variants in whole genome sequencing data adds to the comprehensive description of the mutational landscape of lymphomas and, moreover, establish KDM4C as a putative tumor suppressive gene recurrently altered in subsets of B-cell derived lymphomas.
The lymph node transcriptome of unicentric and idiopathic multicentric Castleman disease
Authors: Horna Pedro , King Rebecca L. , Jevremovic Dragan , Fajgenbaum David C. , Dispenzieri Angela
Published: April 2022

Castleman disease is a polyclonal lymphoproliferative disorder characterized by unicentric or multicentric lymphadenopathy with characteristic histomorphological features, in addition to variable inflammatory symptomatology. The molecular mechanisms and etiologies of unicentric Castleman disease (UCD) and idiopathic multicentric Castleman disease (iMCD) are poorly understood, and identification of targetable disease mediators remains an unmet clinical need. We performed whole exome sequencing on lymph node biopsies from patients with UCD and iMCD and compared the transcriptomic profiles to that of benign control lymph nodes. We identified significantly upregulated genes in UCD (n=443), iMCD (n=316) or both disease subtypes (n=51) and downregulated genes in UCD (n=321), iMCD (n=105) or both (n=10). The transcriptomes of UCD and iMCD showed enrichment and upregulation of elements of the complement cascade. By immunohistochemistry, C4d deposits indicative of complement activation were found to be present in UCD and iMCD, mostly within abnormally regressed germinal centers, but also in association with plasma cell clusters, endothelial cells and stroma cell proliferations. Other enriched gene sets included collagen organization, S1P3 pathway and VEGFR pathway in UCD; and humoral response, oxidative phosphorylation and proteosome in iMCD. Analysis of cytokine transcripts showed upregulation of CXCL13 but not IL6 in UCD and iMCD. Among angiogenic mediators, the VEGFR1 ligand placental growth factor (PGF) was upregulated in both disease subtypes. We hereby report for the first time the whole lymph node transcriptomes of UCD and iMCD, underscoring findings that could aid in the discovery of targetable disease mediators.
Editorial: Let’s not forget
Authors: Naser Md Niamul
Published: April 2022

Abstract not available
Bangladesh J. Zool. 49 (3): 353-354, 2021
Effect of temperature on life cycle and behaviour of Aedes aegypti (Diptera: Culicidae)
Authors: Anee Hafisha Khatun , Ferdous Zannatul , Khandaker Ashfaqul Muid , Alam Mohammad Shamimul , Md Shahjahan Reza
Published: April 2022

In this study, effect of increasing temperature on life cycle, mortality, and behavior of the mosquito species, Aedes aegypti was evaluated. Heat shock was applied at 32°C, 37°C and 42°C for 20 minutes, 1 hour and 2 hours for each temperature to egg, 2nd instar, 3rd instar and pupal stage separately and changes in life cycle pattern was recorded on a routine basis. The control temperature was 27°C at which the mosquito was reared. When heat-shock was applied to eggs, the developmental period for each stage was found to be inversely proportional to temperature rise. The shortest embryonic developmental period was recorded at 32°C, and the shortest larval and pupal stages were recorded at 37°C (2h). The shortest full development period was also found to be at 37°C (2h). No hatching was recorded at 42°C. While heat shock was applied to 2nd instar larvae, 3rd instar larvae and pupae, similar decreased pattern was observed. In this study, 100% viability was observed upon heat shock to eggs, larvae (2nd and 3rd instar) and pupae at 27°C and 32°C. In case of 37°C, egg, 2nd instar and pupal viability decreased. No egg hatched at 42°C, while few 2nd instars survived. Lowest viability rate for 3rd instar larvae and pupae were counted at 42°C. Change in the rate of movement also decreased gradually with increasing temperatures in pupae. The change was irregular in case of 2nd and 3rd instar larvae. The highest movement was recorded for 2nd and 3rd instar larvae at 32°C and 27°C, respectively and lowest was recorded at 42°C.
Bangladesh J. Zool. 49 (3): 369-379, 2021
Kredi Temerrüt Takasları Primi ile BIST 100 Endeksi, Döviz Kuru ve Faiz Arasındaki İlişki: Türkiye Örneği
Authors: ÇETİN Ali Cüneyt
Published: April 2022

Bu çalışmada 2010:04-2021:01 dönemi için Türkiye’nin Kredi Temerrüt Takasları (CDS) priminin, BIST100 endeksi, döviz kuru ve faiz oranı ile olan ilişkisi incelenmiştir. Bu amaçla yapılan Granger nedensellik testi sonucunda CDS primleri ile BIST100 endeksi arasında iki yönlü, CDS primlerinden döviz kuruna doğru tek yönlü nedensellik ilişkisi tespit edilmiştir. CDS primleri ile BIST100 endeksi değişkenlerinin birbirlerinin nedeni, CDS priminin ise döviz kurunun nedeni olduğu görülmüştür. Etki-tepki analizi sonucunda, BIST100 endeksi kaynaklı bir şokun CDS primlerini ikinci dönemin ortasında 0.05 azalttığı, üçüncü ve beşinci dönemin ortasında ise artırdığı belirlenmiştir. CDS primlerinde meydana gelen bir şokun BIST100 endeksini beşinci dönemin ortasına kadar 0.10 artırdığı, döviz kurunu ise beşinci dönemin ortasına kadar 0.08 azalttığı tespit edilmiştir. Varyans ayrıştırmasına göre, kısa ve uzun dönemde CDS primlerindeki değişimin yaklaşık %91’inin kendisi tarafından, %6’sının ise BIST100 endeksi tarafından açıklandığı görülmüştür. BIST100 endeksindeki değişimlerin ilk dönem yaklaşık %65’inin kendi şoklarından kaynaklandığı, %34’ünün ise CDS kaynaklı olduğu, uzun dönemde CDS’in etkisinin yaklaşık %39, faizin etkisinin ise %4 oranında kaldığı belirlenmiştir. Kurdaki değişimlerin ilk dönem yaklaşık %68’lik kısmının kendi şokları tarafından, %30’unun CDS, %0.60’ının ise BIST100 endeksi tarafından açıklandığı, son dönemde kurdaki değişimlerin yaklaşık %42’sinin CDS primleri tarafından, %53’ünün ise kendi şokları tarafından belirlendiği görülmüştür.
AN INQUIRY INTO FLIPPED LEARNING IN FOURTH GRADE MATH INSTRUCTION
Authors: D’addato Teresa , Miller Libbi R.
Published: April 2022

The objective of this action research project was to better understand the impact of flipped learning on fourth grade math students in a socioeconomically disadvantaged setting. A flipped instructional model was implemented with the group of students enrolled in the researcher’s class. Data was collected in the form of classroom observations, teacher reflections and surveys from both parents and students. Findings indicated that a flipped learning methodology shifted the role of the teacher to that of a classroom facilitator. Flipped learning also created an engaging instructional environment, which afforded students the opportunity to experience a greater sense a responsibility over their learning process. While parents responded to flipped learning in mixed ways, they overall reported positive changes in their children as a result of the shift in instructional methods. Conclusions and implications for practice are discussed.
THE ROLE OF KNOWLEDGE BROKERS: LESSONS FROM A COMMUNITY BASED RESEARCH STUDY OF CULTURAL SAFETY IN RELATION TO PEOPLE WHO USE DRUGS
Authors: McCall Jane , Mollison Ashley , Browne Annette , Parker Joanne , Pauly Bernie
Published: April 2022

The study explored cultural safety as a strategy to address the stigma of substance use in acute care settings. Two research team members took on the role of knowledge brokers (KBs) in order to liaise between the research team and two distinct research advisory groups: one with people who use drugs and the other nurses. The KBs were instrumental in ensuring that the research process and outcomes reflected the needs, experiences and aspirations of people who use or have used illicit drugs, and the nurses providing care in hospitals as well as bridging differences in power and privilege between team members and advisory groups.
ADVENTURES IN THE PRINCIPLES OF LEARNING COURSE WIKI: A WIKIOGRAPHY
Authors: Parson Jesse
Published: April 2022

When I first visited the Principles of Learning (Pol) course wiki, I sensed the breadth and depth of the existing posts. The proceeding page has been intentionally left blank. It represents the feeling of dilemma when creating my first, new post. This paper will report on my contributions to the Principles of Learning (PoL) course wiki as a form of reflection on my first semester in the Masters of Education (MEd) program at the University of Ontario Institute of Technology (UOIT). The opening discussion poses the dilemma of first encountering the wiki. The next section describes a series of smaller posts to the wiki while reflecting on the work process of building wiki content. This is followed by a summary of contributions to the wiki featuring people in education: Bill Bigelow (2017), Malcolm Gladwell (2008), John Goodlad (2004), and a discussion of revisionist history. A final section will consolidate what I learned during this process for use in future course work. Anafterword notes additional contributions that I made before 2016 came to a close.
NOT A NOVICE NOW: A WIKI JOURNEY
Authors: Gagné Monica
Published: April 2022

This paper explores the potential for students to engage in social constructivist (Vygotsky, 1978) learning through the development of a course wiki. As a requirement of the Principles of Learning (PoL) course, at the University of Ontario Institute of Technology, students are tasked with building a collection of online, student-authored learning resources. By providing an account of my experiences as a graduate student contributing to a course wiki for the first time, in relation to relevant learning theories, I am able to outline how I progressed from a novice wiki contributor to a confident content creator. In critical reflection, both the hesitancies and achievements I met while taking part in this active learning assignment help to provide insight into the types of obstacles that can occur when working on a course wiki. With a deeper awareness of discovery-based learning and additional scaffolding supports from the instructor, I believe that I could have better engaged with the social constructivist aspects of the wiki and opportunities to collaborate with my peers. Overall, I have found that the course wiki allowed me to take active ownership of my learning while engaging in higher order cognitive processes (Biasutti & EL-Deghaidy, 2012).
Expression of Communicative and Organizational Abilities in Representatives of Dance Sport and Other Dance Styles (Adolescents)
Authors: Ušpurienė Aistė Barbora , Sadzevičiūtė Deimantė
Published: April 2022

The aim of the research. To reveal the expression of communicative and organizational abilities in representatives of dance sport and other dance styles (ballet, street, modern, national, lindy hop) (adolescents).
Methods. The research involved 50 adolescents (28 girls and 22 boys) that attended dance sport, and 50 participants (30 girls and 20 boys) that attended dance of other styles (ballet, street, modern, national, lindy hop). The age of the research participants was 12–14 years. The questionnaire was compiled according to the methodology of Fedorishin and Sinyavskiy (2017), aiming to assess communicative and organizational abilities. The abilities of the dancers assessed according to this methodology were classified as “very low”, “low”, “average”, “upper average” and “high” levels.
Results. After assessing the communicative abilities in the research participants of dance sport in the aspect of gender, we determined that the communicative abilities in most girls (36.42 per cent) and boys (37.50 per cent) were high. After assessing their organizational abilities, it was determined the organizational abilities in most researched (37.48 per cent of the boys and 45.49 per cent of the girls) matched to the low level. Among the research participants of other dance styles, the level of communicative abilities was high in 30.00 per cent of the boys and 24.98 per cent of the girls. After assessing the organizational abilities of this group of dancers, it was determined the low level of organizational abilities was most expressed, matching 30.24 per cent of the boys and 64.86 per cent of the girls.
Conclusions. After assessing the adolescents that attended dance sport or dance of other styles, it was determined the level of communicative and organizational abilities among the research participants of those groups did not differ statistically significantly.
Key words: dance sport, other dance styles, communicative abilities, organizational abilities.
Application of Biotechnology in Specific Spoilage Organisms of Aquatic Products
Authors: Dong Huina , Gai Yuanming , Fu Shaoping , Zhang Dawei
Published: April 2022

Aquatic products are delicious and have high nutritive value, however, they are highly perishable during storage due to the growth and metabolism of microorganisms. The spoilage process of aquatic products was demonstrated to be highly related to the composition of microorganisms, in which the specific spoilage organisms (SSOs) are the main factors. In this article, the spoilage indicators of SSOs were systematically described, which could make a comprehensive evaluation of the quality of aquatic products. Quorum sensing (QS) regulates the growth, metabolism and characteristics of SSOs, the common signaling molecules and the QS system in the major SSOs of aquatic products were discussed. Moreover, we compared various technologies for the analysis of SSOs in aquatic products. Besides, quality control techniques based on microbiota regulating of aquatic products, including physical, chemical and biological preservation strategies, were also compared. In conclusion, novel preservation technologies and hurdle techniques are expected to achieve comprehensive inhibition of SSOs.
Bioinformatic Analysis of the Perilymph Proteome to Generate a Human Protein Atlas
Authors: van Dieken Alina , Staecker Hinrich , Schmitt Heike , Harre Jennifer , Pich Andreas , Roßberg Willi , Lenarz Thomas , Durisin Martin , Warnecke Athanasia
Published: April 2022

The high complexity of the cellular architecture of the human inner ear and the inaccessibility for tissue biopsy hampers cellular and molecular analysis of inner ear disease. Sampling and analysis of perilymph may present an opportunity for improved diagnostics and understanding of human inner ear pathology. Analysis of the perilymph proteome from patients undergoing cochlear implantation was carried out revealing a multitude of proteins and patterns of protein composition that may enable characterisation of patients into subgroups. Based on existing data and databases, single proteins that are not present in the blood circulation were related to cells within the cochlea to allow prediction of which cells contribute to the individual perilymph proteome of the patients. Based on the results, we propose a human atlas of the cochlea. Finally, druggable targets within the perilymph proteome were identified. Understanding and modulating the human perilymph proteome will enable novel avenues to improve diagnosis and treatment of inner ear diseases.