bluuebunny/crossref_metadata_2025 huggingface dataset:
Ayurvedic approach for managing Indralupta (Alopecia Areata): A Case Study
Authors: Pal Subodh , Paradkar Hemant , Attar Sajida , Pathrikar Anaya
Published: January 2024

Indralupta (Alopecia areata) is a disease characterised by patches of hair loss spread throughout the body and scalp described as Shirogata Roga (diseases of head) & Kapalagata Roga (Scalp disease) by Acharyas. It can be considered alopecia areata according to conventional medicine. Alopecia areata is considered autoimmune, making it difficult to treat with increased chances of recurrence. But Ayurveda is very effective with no side effects and minimal chances of recurrence as it not only treats the disease but also works on the causative factors (Nidan Parivarjana). The present case report is on the effectiveness of Shaman (treatment that pacifies the aggravated Doshas), Keshya (Hair nourishing treatment), and Raktamokshna (blood-letting) in the patient of Indralupta. A 16-year-old boy who had hairless patches on his scalp was diagnosed with Alopecia areata 4 years before by a dermatologist. He already took conventional modern medicines but didn’t get a satisfactory result. It showed recurrence after the stoppage of medicines. So, he came to Kayachikitsa OPD for Ayurvedic treatment. After 4 months of Shamana Chikitsa, Jalaukavcharan (Leech therapy), Nasya (medicine administered through nasal route), and Shirolepa (local application of Ayurveda herbs), complete recovery was seen with no adverse effects during and after treatment. In this case, hair regrowth from hair follicles was evident within 30 days of treatment. The collected data of this study suggest that Shamana treatment, Raktmokshan, and Keshya medicine can provide complete relief in Indralupta.
A randomized controlled clinical study to evaluate the efficacy of Yastimadhu Hydrogel in Parikartika vis-a-vis Fissure-in-Ano
Authors: Vinayakumar Anveri  , Sudeepa  , D. Gururaja Tantry
Published: January 2024

Parikartika, commonly known as Fissure-in-Ano, ranks among the prevalent anorectal disorders and represents a painful affliction affecting the anal region. Its clinical presentation bears a striking resemblance to the description of Parikartika in Ayurvedic texts. Contemporary therapeutic approaches involve the application of local soothing agents, oral analgesics, and stool softeners during the initial stages. Surgical interventions, including Lord’s dilation, fissurectomy, and sphincterotomy, are considered in more advanced cases. Ayurveda, on the other hand, advocates the use of various drugs with distinct properties for treating this condition, with Yashtimadhu being recognized for its Vrana Ropan, Mrudukara, Tvak Prasadana, and Pitta-Anila Hara properties. Recognizing the regenerative potential of hydrogels on the skin, our study sought to evaluate and compare the local effects of Yashtimadhu hydrogel and Yashtimadhu Ghrita in the management of Parikartika. A randomized comparative study was conducted involving 60 patients with Fissure-in-Ano, divided into two groups. The trial group (n=30) received Yashtimadhu hydrogel through local application for a period of 3 weeks, while the control group (n=30) underwent treatment with Yashtimadhu Ghrita during the same duration. Assessment of symptoms such as Pain, Bleeding, Constipation, Itching, Discharge, and the size of anal fissure, along with observations on the anal fissure floor and granulation tissue, revealed promising results. Statistical analysis indicated the effectiveness of both Yashtimadhu hydrogel and Yashtimadhu Ghrita in the conservative management of Parikartika. Notably, Yashtimadhu Ghrita emerged as a more potent remedy in the management of anal fissure when compared to Yashtimadhu hydrogel.
UTILIZING EXPERIMENTAL COMBINATION DESIGN: OPTIMIZATION OF FOOD BAR RECIPE BASED ON PURPLE SWEET POTATO
Authors: Widyaningsih Tri Dewanti , Fibrianto Kiki , Honestin Trifena , Sigalingging Catherine Novita Sari
Published: January 2024

Modern food technology can create nutritious goods that are useful and simple to consume. Food bars are convenient, calorie-dense, and healthy items. It is usually made from a variety of culinary ingredients combined and then molded into a sturdy, handy product. The goal of this study is to create a food bar using a blend of dried strawberries (DS), moringa flour (MF), mung bean flour (MBF), and purple sweet potato paste (PSPP). The formulation of DS, MBF, MF, and PSPP was improved by utilizing a mixture design of experiments with Minitab software. The predicted outcomes of this formulation are maximal antioxidant activity, maximum total flavonoids, and maximum total phenolic. Using 54.84% purple sweet potato paste (PSPP), 6.21% moringa flour (MF), 33.95% mung bean flour (MBF), and 5.00% dried strawberries (DS) allowed for an ideal maximal antioxidant activity. The antioxidant activity was 16.44 mg TE/g; the total flavonoid was 11.35 mg QE/g; and the total phenolic was 10.70 mg GAE/g.
Influência da incorporação de resíduos de construção e demolição funcionalizados com material de mudança de fase nas propriedades mecânicas de betões
Authors: Aguiar J. , Cunha S. , Jia Z.Y.
Published: January 2024

O crescimento das urbanizações levou ao rápido desenvolvimento da indústria da construção, originando uma grande quantidade de resíduos de construção e demolição (RCD) e em simultâneo um aumento nos consumos energéticos e emissões de dióxido de carbono (CO2) para a atmosfera. A aplicação simultânea de RCD e tecnologias de calor latente incorporadas em betões permite a reutilização de agregados reciclados, mas também minimizar o consumo de energia durante o período de utilização do edifício. Este estudo tem como principal objetivo a avaliação da incorporação de material de mudança de fase (PCM) em agregado reciclado proveniente de RCD, utilizado em substituição do agregado natural para a produção de betões, assim como a avaliação do comportamento mecânico dos betões produzidos. A incorporação de PCM no agregado reciclado foi efetuada segundo duas técnicas distintas, a vácuo e a pressão atmosférica, sendo produzidos betões com os diferentes agregados. Foi possível verificar que a presença do agregado reciclado dopado com PCM afetou negativamente o desempenho mecânico das diferentes formulações de betão desenvolvidas.
The Monitoring of Supply Chains Using Blockchain Technology,with Special Reference to Food Sectors
Authors: Abhishek Srivastava  , S. L. Gupta
Published: January 2024

The most observed part associated with supply chain companies those are facing issues and challenges like mistakescommitted by human, abnormal delays in production data, information updates or sharing, be deficient with accountability,fortification, momentum with delivery of products and services, monitoring and tracking of the sources for goods andservices etc. With this research paper, our study is to examine the position of blockchain in supply chain management alongwith the issues associated with supply chain management practices and blockchain / supply chain disadvantages. Here it hasbeen observed that transparency with supply chain as well as chain of guardianship can be improved by the advent ofblockchain technology adoption. With this paper, a model has been proposed for the Tracing of Safety in Food Supply Chainwith System Design and Implementation that compares it with the available technologies in food sectors.
Analytics's Function in Social Media Branding and Marketing
Authors: Parimal Priya Ranjan  , Abhishek Srivastava
Published: January 2024

Today, everything is traceable online viz web assets, social media profiles and other digital marketing initiatives may all belinked to and tracked. It is quite amazing how much data marketers can access today. The majority of organisations relyheavily on digital marketing analytics to build an online presence that promotes the promotion of their brand and business.Without data analysis, your marketing activities won't yield the optimum results. You must create a strategy and becomeaddicted to analysing and understanding the facts. By doing so, you may evaluate the efficacy of your marketing initiativesand decide whether you need to revise your plans or tactics. Digital marketing analytics gives a way to assess success. Withthe use of these technologies, one can learn which content is effective, where target audience is situated, which channels havethe highest levels of interaction, and the steps audience can take to convert into paying customers.
Information Technology Enablement of Indian Police Department
Authors: Aditya Kumar Gupta
Published: January 2024

Application of Information Technology in the department of police is surely an idea that will be would help in their primarytask, which is about to control and prevent crime in society. It would also help the police department to create a better andmore intelligent system for the detection of crime in advance and to investigate it. The applications of IT would also help thepolice department to optimize its efforts, personnel, and resources.The police department is established to maintain a secure environment with disciplinary approaches and well-definedtraditional parameters. But with the advancement of new cyber threats, the necessity for the IT sector in the police departmenthas increased. Information technology influenced the whole spectrum of society, each corner of the educational field, andtrading services to a great extent which enhance the need for skill in every aspect of opportunities for development.Information Technology refers to the use application of computers to analyze, store and transmit valuable information,viewing the part of the world into a single entity of the market. Its major role in the education system has introduced abreakthrough in acknowledgment areas and produced a variety of opportunities. The major objective of using informationtechnology in the police department is to determine and describe the role of IT for better achievements in the area of Safetyand Security by enabling it to the police department. There is a requirement for the management of data in a prudent mannerso that it could be used for future studies and prediction of crime. The high-end integrated IT solutions have generated widescope of sustainability which leads to the growth of IT services, where enterprise problem-solving and skilled systemsincorporated, are expected to fuel growth in this segment.
Customers Views on Covid-19's Food Delivery Applications' Quality Assessment
Authors: Mukta Goyal  , Tanwangini Sahani
Published: January 2024

Online users can use a website or an online application to order food for delivery or takeout from a nearby restaurant. Itresembles online consumer product purchases in certain aspects. Cash, debit cards, or credit cards are accepted as forms ofpayment, and a portion of the money is given to the online food company. The study focuses on companies that offer fooddistribution services and carry out service activities including food delivery to clients and food sales as items. BecauseGeneration Z is predominately made up of self-employed people who lack the time to cook a meal, food delivery services areimportant in their lives.The study's importance lies in understanding the positive and bad effects that the COVID scenario and lockdown have had onthem. The study aids in understanding the numerous marketing initiatives launched by the major online meal deliveryservices in an effort to boost sales and foster client loyalty. This study also focuses on the different safety precautions thatonline food delivery services take to guarantee the security of their delivery personnel, the restaurants they work with, thecustomers, and the quality of the food, as well as the viability of such services both during Covid and generally.
Anamnesis Of How India Dealt And Paved Entrepreneurial Opportunities During The Pandemic Covid-19
Authors: Jyotsna Rai  , Rakesh Kumar Yadav
Published: January 2024

The Covid-19 proved to the world as a real pandemic affecting millions of people worldwide. India, the st second-most populous nation globally, also suffered severely from the disease covid-19. As of 31 of December 2020, India was investigated with 10,305,674 confirmed cases, and the death toll was 1,48,738. More than 20 thousand confirm cases from covid-19 were in December itself across the nation. Like other nations, India went through a different lockdown and unlocked rules and regulations, adversely affecting human life and the economy. People realised that human sustenance on limited means was never challenging, but then it had repercussions from economic aspects. Here, we attempt to discuss how India dealt and would probably deal with the significant financial and human life issues during and post covid-19. Additionally, how this pandemic proved to be a boon for some and created entrepreneurial opportunities for them. This paper is a glance at the update on India's Covid-19 vaccine and the massive inoculation drive 2021.
Growing Imperative of Digital Payments In COVID-19 Pandemic-With Special Reference To Retail Customers
Authors: Abhishek Kumar Singh
Published: January 2024

The impact of steps taken to contain COVID-19 and the fear of losing lives, on consumption and paymentpatterns is quite evident in India. The lockdown has changed the consumption and payment habits ofconsumers. The study was conducted to assess the impact of COVID-19 on payment patterns (retail) ofconsumers residing in urban areas of Varanasi and nearby towns. The required data was collected through anonline survey. The questionnaire to assess the impact of pandemic on payments patterns (retail) was sent tourban consumers of Varanasi and nearby towns (U.P.), using Google forms. Some of the consumer'sresponses were recorded using telephonic interview. The data collected was analysed through MS-Exceland Jamovi version 1.6.23 software. To avoid physical contact, people have started digital payments,especially UPI/ Digital Wallets. The digital payments are used for both goods purchasing and servicesconsumption and this behavior is likely to be continued in future also. There are some limitations also suchas security threats, connectivity issues etc, which need to be improved. Due to administrative restrictionsand social distancing mandates, small sample was selected for the study. The study has taken only urbanconsumers as sample. The findings will help marketers to adapt accordingly and concerned authorities todevelop the necessary infrastructure for encouraging the digital payments among people.
Impact of Covid Storm on Indian Tourism Industry
Authors: Divya Vats
Published: January 2024

The tourism industry of India is the most rapid rising industry, which drive economic development, andmajor source of foreign exchange, increasing employability. It contributes more than 247 billion U.S.dollars to the Indian GDP in 2019 and was to be double in upcoming years. Diversity of Climate as well asculture & cuisines, Beauty & adventure of nature, historic past and medical tourism moreover, awarenessand marketing initiatives such as the Incredible India campaign along with e-visa options, attractsInternational and domestic tourist, but this COVID storm broke down the chain. This present research studyis an analytical assessment of the COVID storm and its impact on tourism Industry in India. There is aworthy analysis of what tourism industry was, how it contributes to economy, how it affects theemployment, business and overall economic development of country and what is the current satiation of theIndian tourism industry. There has been an extraordinary development opportunity of tourism in India due tothe efficient government policies and effective support from all levels. The present study also proposedsome recommendations for speedy recovery and regain of the tourism industry which can be helpful forrevamping economy to achieve the take off again in new normal.
Perceived Benefits and Pitfalls of Telecommuting Practices: Information Technology Professionals' Perspectives
Authors: Prakash Shrestha
Published: January 2024

The aim of this paper is to explore the perceived benefits and pitfalls of telecommuting from the perspectiveof Nepalese IT professionals. A network sampling approach was used to collect the data from the top 10 ITcompanies of Nepal. The questionnaire was distributed to 250 telecommuters and completed by 193(77.20%). Telecommuters can reap many benefits as a result of telecommuting practices. They can bettermanage their time and schedules, improve their quality of life, and arrange for the supervision of familymembers. Telecommuting provides them with the flexibility they require to perform their jobs effectively.By implementing such practices, telecommuters can save money on transportation as well as time andenergy spent commuting to work. Because of lower stress levels, increased motivation, professionalflexibility, a better working environment, and independence, they can gain access to global talent, reducetardiness, improve health, and pursue a hobby or a profession. Telecommuters may encounter a variety ofpitfalls as a result of telecommuting practices. Because of a lack of face-to-face communication, regularsupervision, and constant interaction, they may feel isolated and frustrated. They could be required to workin a detached or separate society. They may struggle to keep their professional and personal lives separate.They must also give up their living space and forego certain job perks. Workplace changes can createdifficulties to perform well. To reap the benefits of telecommuting, today's companies must avoid suchpitfalls. Companies must create new and innovative systems to make them work and train employees to becomfortable with such practices. They should devise a method for monitoring and tracking the process, andproviding needed guidance.
Learning From International Comparators of National Medical Imaging Initiatives for AI Development: Multiphase Qualitative Study
Authors: Karpathakis Kassandra , Pencheon Emma , Cushnan Dominic
Published: January 2024

Background

The COVID-19 pandemic drove investment and research into medical imaging platforms to provide data to create artificial intelligence (AI) algorithms for the management of patients with COVID-19. Building on the success of England’s National COVID-19 Chest Imaging Database, the national digital policy body (NHSX) sought to create a generalized national medical imaging platform for the development, validation, and deployment of algorithms.

Objective

This study aims to understand international use cases of medical imaging platforms for the development and implementation of algorithms to inform the creation of England’s national imaging platform.

Methods

The National Health Service (NHS) AI Lab Policy and Strategy Team adopted a multiphased approach: (1) identification and prioritization of national AI imaging platforms; (2) Political, Economic, Social, Technological, Legal, and Environmental (PESTLE) factor analysis deep dive into national AI imaging platforms; (3) semistructured interviews with key stakeholders; (4) workshop on emerging themes and insights with the internal NHSX team; and (5) formulation of policy recommendations.

Results

International use cases of national AI imaging platforms (n=7) were prioritized for PESTLE factor analysis. Stakeholders (n=13) from the international use cases were interviewed. Themes (n=8) from the semistructured interviews, including interview quotes, were analyzed with workshop participants (n=5). The outputs of the deep dives, interviews, and workshop were synthesized thematically into 8 categories with 17 subcategories. On the basis of the insights from the international use cases, policy recommendations (n=12) were developed to support the NHS AI Lab in the design and development of the English national medical imaging platform.

Conclusions

The creation of AI algorithms supporting technology and infrastructure such as platforms often occurs in isolation within countries, let alone between countries. This novel policy research project sought to bridge the gap by learning from the challenges, successes, and experience of England’s international counterparts. Policy recommendations based on international learnings focused on the demonstrable benefits of the platform to secure sustainable funding, validation of algorithms and infrastructure to support in situ deployment, and creating wraparound tools for nontechnical participants such as clinicians to engage with algorithm creation. As health care organizations increasingly adopt technological solutions, policy makers have a responsibility to ensure that initiatives are informed by learnings from both national and international initiatives as well as disseminating the outcomes of their work.
Comparing Self-Reported Running Distance and Pace With a Commercial Fitness Watch Data: Reliability Study (Preprint)
Authors: Bullock Garrett , Stocks Joanne , Feakins Benjamin , Alizadeh Zahra , Arundale Amelia , Kluzek Stefan
Published: January 2024

BACKGROUND

There is substantial evidence exploring the reliability of running distance self-reporting and GPS wearable technology, but there are currently no studies investigating the reliability of participant self-reporting in comparison to GPS wearable technology. There is also a critical sports science and medical research gap due to a paucity of reliability studies assessing self-reported running pace.

OBJECTIVE

The purpose of this study was to assess the reliability of weekly self-reported running distance and pace compared to a commercial GPS fitness watch, stratified by sex and age. These data will give clinicians and sports researchers insights into the reliability of runners’ self-reported pace, which may improve training designs and rehabilitation prescriptions.

METHODS

A prospective study of recreational runners was performed. Weekly running distance and average running pace were captured through self-report and a fitness watch. Baseline characteristics collected included age and sex. Intraclass correlational coefficients were calculated for weekly running distance and running pace for self-report and watch data. Bland-Altman plots assessed any systemic measurement error. Analyses were then stratified by sex and age.

RESULTS

Younger runners reported improved weekly distance reliability (median 0.93, IQR 0.92-0.94). All ages demonstrated similar running pace reliability. Results exhibited no discernable systematic bias.

CONCLUSIONS

Weekly self-report demonstrated good reliability for running distance and moderate reliability for running pace in comparison to the watch data. Similar reliability was observed for male and female participants. Younger runners demonstrated improved running distance reliability, but all age groups exhibited similar pace reliability. Running pace potentially should be monitored through technological means to increase precision.
Selecting an Ecological Momentary Assessment Platform: Tutorial for Researchers (Preprint)
Authors: Henry Lauren M , Hansen Eleanor , Chimoff Justin , Pokstis Kimberly , Kiderman Miryam , Naim Reut , Kossowsky Joe , Byrne Meghan E , Lopez-Guzman Silvia , Kircanski Katharina , Pine Daniel S , Brotman Melissa A
Published: January 2024

BACKGROUND

Although ecological momentary assessment (EMA) has been applied in psychological research for decades, delivery methods have evolved with the proliferation of digital technology. Technological advances have engendered opportunities for enhanced accessibility, convenience, measurement precision, and integration with wearable sensors. Notwithstanding, researchers must navigate novel complexities in EMA research design and implementation.

OBJECTIVE

In this paper, we aimed to provide guidance on platform selection for clinical scientists launching EMA studies.

METHODS

Our team includes diverse specialties in child and adolescent behavioral and mental health with varying expertise on EMA platforms (eg, users and developers). We (2 research sites) evaluated EMA platforms with the goal of identifying the platform or platforms with the best fit for our research. We created a list of extant EMA platforms; conducted a web-based review; considered institutional security, privacy, and data management requirements; met with developers; and evaluated each of the candidate EMA platforms for 1 week.

RESULTS

We selected 2 different EMA platforms, rather than a single platform, for use at our 2 research sites. Our results underscore the importance of platform selection driven by individualized and prioritized laboratory needs; there is no single, ideal platform for EMA researchers. In addition, our project generated 11 considerations for researchers in selecting an EMA platform: (1) location; (2) developer involvement; (3) sample characteristics; (4) onboarding; (5) survey design features; (6) sampling scheme and scheduling; (7) viewing results; (8) dashboards; (9) security, privacy, and data management; (10) pricing and cost structure; and (11) future directions. Furthermore, our project yielded a suggested timeline for the EMA platform selection process.

CONCLUSIONS

This study will guide scientists initiating studies using EMA, an in vivo, real-time research tool with tremendous promise for facilitating advances in psychological assessment and intervention.
Learning From International Comparators of National Medical Imaging Initiatives for AI Development: Multiphase Qualitative Study (Preprint)
Authors: Karpathakis Kassandra , Pencheon Emma , Cushnan Dominic
Published: January 2024

BACKGROUND

The COVID-19 pandemic drove investment and research into medical imaging platforms to provide data to create artificial intelligence (AI) algorithms for the management of patients with COVID-19. Building on the success of England’s National COVID-19 Chest Imaging Database, the national digital policy body (NHSX) sought to create a generalized national medical imaging platform for the development, validation, and deployment of algorithms.

OBJECTIVE

This study aims to understand international use cases of medical imaging platforms for the development and implementation of algorithms to inform the creation of England’s national imaging platform.

METHODS

The National Health Service (NHS) AI Lab Policy and Strategy Team adopted a multiphased approach: (1) identification and prioritization of national AI imaging platforms; (2) Political, Economic, Social, Technological, Legal, and Environmental (PESTLE) factor analysis deep dive into national AI imaging platforms; (3) semistructured interviews with key stakeholders; (4) workshop on emerging themes and insights with the internal NHSX team; and (5) formulation of policy recommendations.

RESULTS

International use cases of national AI imaging platforms (n=7) were prioritized for PESTLE factor analysis. Stakeholders (n=13) from the international use cases were interviewed. Themes (n=8) from the semistructured interviews, including interview quotes, were analyzed with workshop participants (n=5). The outputs of the deep dives, interviews, and workshop were synthesized thematically into 8 categories with 17 subcategories. On the basis of the insights from the international use cases, policy recommendations (n=12) were developed to support the NHS AI Lab in the design and development of the English national medical imaging platform.

CONCLUSIONS

The creation of AI algorithms supporting technology and infrastructure such as platforms often occurs in isolation within countries, let alone between countries. This novel policy research project sought to bridge the gap by learning from the challenges, successes, and experience of England’s international counterparts. Policy recommendations based on international learnings focused on the demonstrable benefits of the platform to secure sustainable funding, validation of algorithms and infrastructure to support in situ deployment, and creating wraparound tools for nontechnical participants such as clinicians to engage with algorithm creation. As health care organizations increasingly adopt technological solutions, policy makers have a responsibility to ensure that initiatives are informed by learnings from both national and international initiatives as well as disseminating the outcomes of their work.
Comparison between metformin and glibenclamide as antidiabetic oral in gestational diabetes mellitus: a review
Authors: Ridhayani Firda , I Dewa Agung Ayu Diva Candraningrat  , Ilmi Nurhafizah  , Karina Nurlitasari  , Mardiana Siregar
Published: January 2024

Gestational diabetes mellitus (GDM) is one of the most frequent clinical complications during pregnancy that affects up to 6% of women with pregnancies around the world. Gestational diabetes mellitus treatment used insulin as first-line therapy. In addition, several professional associations are also considering treatment using antidiabetic oral which has equivalent efficacy compared with insulin. However, many oral antidiabetic recommendations have been administered to treat GDM, including metformin and glyburide or glibenclamide. This article’s review aims to compare the usage between metformin and glyburide or glibenclamide in GDM patients. This review compared research results from PubMed as literature resources and the PRISMA flow chart as the protocol for the article selection process. Based on inclusion and exclusion criteria there are six research articles that are appropriate to the article’s topic and aim. Metformin is superior compared with glyburide or glibenclamide administration as antidiabetic oral in GDM. Metformin showed a significant effect in lowering preprandial and postprandial glucose level, elevating insulin sensitivity, while glibenclamide administration decreased dynamic pancreatic β-cell responsivity significantly and had a higher risk compared with insulin and metformin.
Effectiveness of azithromycin and ciprofloxacin in the treatment of typhoid fever: a systematic review
Authors: Mulyono Bethea Manuela , Ita Margaretha Nainggolan  , Linawati Hananta  , Lucky Hartati Moehario
Published: January 2024

Typhoid fever or commonly referred to as enteric fever is a systemic disease caused by Salmonella typhi. It often occurs in developing countries due to poor sanitation. Second-line antibiotics, including ciprofloxacin, have been widely used as the first choice treatment for typhoid fever. However, S. typhi has increased resistance to second-line antibiotics, so azithromycin has become an alternative treatment for the typhoid fever. This systematic review assessed the effectiveness of azithromycin and ciprofloxacin against typhoid fever in adults. This research used the PRISMA protocol with predefined Pubmed, Proquest, and EBSCO keywords. After removing duplicates and selecting studies according to inclusion and exclusion criterias, 17 studies about the effectiveness of azithromycin and ciprofloxacin in typhoid fever in adults from 1988-2020 were gathered.  Studies were evaluated using JBI Critical Appraisal Tools. The results showed that administration of azithromycin and ciprofloxacin for typhoid fever yields average length of fever (3.5 d and 4.2 d) and average length of stay (9.3 d and 10 d), respectively. The susceptibility of S. typhi to azithromycin was 99.9%, whereas a significant decrease in its susceptibility to ciprofloxacin was observed in 2017-2020, from 4% to 2%. Azithromycin showed better effectiveness than ciprofloxacin in treating typhoid fever in adults based on S. typhi’s susceptibility, average length of fever and average length of stay from 17 studies reviewed.
Korelasi Konsentrasi Testosteron Darah terhadap Kualitas Semen Segar Ayam Kampung Unggul Balitbangtan (KUB) dengan Fenotip Berbeda
Authors: Magfira Magfira , Karja Ni Wayan Kurniani , Arifiantini R. Iis , Sartika Tike
Published: January 2024

Ayam KUB adalah ayam hasil seleksi dari Balai Penelitian Ternak Ciawi yang memiliki perbedaan fenotip seperti bentuk jengger dan warna bulu. Perbedaan fenotip berpengaruh terhadap konsentrasi testosteron sehingga memengaruhi kualitas semen segar ayam KUB. Penelitian ini bertujuan untuk mengkaji pengaruh fenotip terhadap kualitas semen segar dan testosteron serta korelasinya. Sebanyak 20 ekor ayam KUB umur 1,5 tahun terbagi atas 4 kelompok perlakuan fenotip masing-masing 5 ekor yaitu jengger tunggal bulu penutup merah (JTBM), jenggger tunggal bulu penutup putih (JTBP), jengger pea bulu penutup merah (JPBM), dan jengger pea bulu penutup putih (JPBP). Peubah yang diamati adalah volume, warna, pH dan konsistensi, gerakkan massa, motilitas, viabilitas, abnormalitas dan konsentrasi ejakulat, konsentrasi testosteron dan panjang taji. Hasil penelitian menunjukkan pejantan dengan fenotip JPBM memiliki volume ejakulat paling tinggi dan JTBM adalah yang paling rendah (P<0.05). Pejantan berjengger tunggal memiliki pH lebih tinggi dibandingkan pejantan berjengger pea. Pejantan JTBM juga memiliki motilitas dan konsentrasi ejakulat paling rendah dibandingkan dengan fenotipe lainnya dan untuk peubah warna semen, gerakan massa, viabilitas dan abnormalitas tidak berbeda pada semua fenotip. Panjang taji kiri pejantan JTBP lebih pendek dibandingkan ketiga pejantan lainnya (P<0.05). Ukuran taji berkorelasi positif dengan konsentrasi testosteron dengan kisaran nilai r = 0.33-0.56. Konsentrasi testosteron berkorelasi postif dengan warna (r=0.76), konsentrasi ejakulat (r= 0.44), konsistensi semen (r=0.75) dan motilitas spermatozoa (r= 0.46). Kesimpulan dari penelitian ini adalah pejantan JTBM memiliki kualitas semen segar kurang baik dibandingkan dengan ketiga kelompok pejantan lainnya. Ukuran taji bisa digunakan untuk memprediksi konsentrasi testosteron pada ayam jantan.
Deteksi White Spot Syndrome Virus pada Lobster Menggunakan Primer Kit IQ2000™
Authors: Hidayat Nandar , Apada Andi Magfira Satya , Alwi Danawir , Amriani Rini , Rell Fedri
Published: January 2024

Lobster adalah salah satu jenis bahan pangan yang menjadi komoditas ekspor tertinggi. Lobster dapat diinfeksi oleh White Spot Syndrome Virus yang menyebabkan kematian dan kerugian ekonomi. Penelitian ini untuk mendeteksi adanya infeksi White Spot Syndrome Virus pada lobster di Balai Besar Karantina Ikan dan Pengendalian Hasil Mutu Makassar. Sebanyak 3 sampel lobster Panulirus spp diperiksa secara molekular. Deteksi White Spot Syndrome Virus dilakukan dengan menggunakan Primer Kit IQ2000™ pada mesin Polymerase Chain Reaction. Sampel positif terinfeksi White Spot Syndrome Virus ditandai dengan pita pada agar gel yang terbentuk dengan ukuran 296 bp dan 550 bp, sampel negatif jika pita yang terbentuk berada pada 848 bp. Hasil yang diperoleh setelah eletroforesis sampel pada gel agaros 1% ditemukan adanya pita yang berukuran 848 bp yang menunjukan hasil negatif. Berdasarkan hasil pengujian diatas dapat disimpulkan bahwa ketiga sampel lobster yang diperiksa di Balai Besar Karantina Ikan dan Pengendalian Hasil Mutu Makassar tidak terinfeksi White Spot Syndrome Virus.
Study of Risk Level Death Based on Clinical Symptoms in Cases of Canine Leptosprirosis in Jakarta, Depok and South Tangerang: Data from January-August 2020
Authors: Retnowati Ambar , Indrawati Agustin , Kesumawati Upik , Safika Safika , Wibowo Pratitis S , Noor Susan M , Saepuloh Uus
Published: January 2024

Leptospirosis is a zoonotic disease caused by bacteria Leptospira sp. which causes infection in animals and humans. Dogs infected with leptospirosis showed symptoms such as anorexia, fever, vomiting, weakness, diarrhea and often experience yellowing of the eye area and mucosa around the mouth (icteric) with fatal systemic complications and multi-organ dysfunction, especially in the kidneys and liver. Leptospirosis is an endemic disease in Jakarta. This study aims to identify risk factors that can contribute to canine mortality based on early clinical symptoms that are found when the dog is in an animal health service facility such as a veterinary clinic, veterinary hospital, or independent practice veterinarian. Method was used in this study is clinical manifestations and laboratory examinations and medical records of dogs with suspected leptospirosis. Criteria inclusions were based on aspects of the clinical symptoms of dogs in and around Jakarta. Analysis data used the chi-square with confidence of interval (CI) 95%. Dogs used during the study had ages for puppies (less than 1 year) totaling 13 or 32.50%, for adult dogs over 1 year amounted to 27 or 67.50%, 80% male dogs and 20% female. with 80% maintenance system not housed by the owner. And the conclusion is risk factors for clinical symptoms such as myalgia, symptomatic vomiting of the pulmonary area or shortness of breath and abdominal pain, conjunctival suffusion, anorexia and diarrhea contributed to the high mortality rate leptospirosis during study in dogs 2020.
Current Symptoms and Pathological Changes of Bursa Fabricius from Commercial Farming Broilers Led to Infectious Bursal Disease
Authors: Damairia Bernike Anggun , Putri Khrisdiana , Sutrisno Bambang , Wibowo Michael Haryadi
Published: January 2024

Infectious Bursal Disease (IBD) or Gumboro is caused by the IBD virus of the Birnaviridae family. The disease is acute and highly contagious in young birds. The virus infection causes severe damage to the lymphoid organs i.e. bursa Fabricius leading to immunosuppression. The disease morbidity may reach 100%, while the mortality varies from 20 to 100%, causing high economic losses. Infectious Bursal Disease has remained significant threat although vaccination has been applied. This study aimed to determine the current typical pathological changes in the bursa Fabricius of commercial broilers showing IBD symptoms. The samples were obtained from commercial broiler farms in Sragen, Wonogiri, Batang, and Sleman. Gross lesion examination showed enlargement of the bursa Fabricius with gelatinous material on the serosal surface, oedema with fluid accumulation in the lumen, hemorrhages of the serosal surface, atrophy, and caseous exudate in the lumen. Histopathologic changes of acute IBD include hemorrhages, congestion, lymphocyte necrosis, accumulation of fibrin, oedematous and heterophils infiltration in the interfollicular tissues. Microscopic changes in chronic IBD (5-7 days post infection IBDV) including follicular atrophy, lymphocyte necrosis, vacuolization of the follicle, and proliferation of fibroblast and connective tissue in the interfollicular space.   In conclusion, the notable pathological change description of    bursa Fabricius in suspected acute is gross lesion (swelling and edema, thickened and enlarged plica bursa Fabricius, hemorraghe), microscopic lesion (congestion, hemorraghe, heterophil infiltration) or chronically IBD infection in broiler chicken was gross lesion (atrophy bursa Fabricius, atrophy and excudate casouse in the lumen bursa Fabricius), microscopic lesion (lymphocyte necrosis, vacuolization of bursa Fabricius follicles, proliferation of fibroblasts and interfollicular connective tissue).
Kemampuan Rectovaginal Endoscopy (RVE) Mendeteksi Berahi dan Gambaran Kadar Estrogen Selama Siklus Berahi Kambing
Authors: Nurcahya Dony , Nugroho Widagdo Sri , Budiyanto Agung , Pramono Budi
Published: January 2024

Deteksi estrus yang tepat pada kambing akan menentukan keberhasilan inseminasi buatan (IB). Rectovaginal endoscopy (RVE) merupakan alat deteksi estrus pada kambing yang dimodifikasi dengan perpaduan spekulum yang dilengkapai kamera terhubung dengan layar monitor. Alat RVE ini membantu peternak memastikan saat IB yang tepat. Penelitian ini bertujuan untuk mengetahui kemampuan Rectovaginal endoscopy (RVE) untuk mendeteksi gejala estrus pada  kambing-domba dan mengetahui gambaran estrogen selama siklus berahi kambing-domba. Metode penelitian dengan membandingkan deteksi estrus menggunakan kawin alami dengan pejantan (kelompok 1, kontrol) dengan konvensional/penglihatan mata langsung (Kelompok 2) dan RVE (kelompok 3). Masing-masing kelompok menggunakan 16 ekor kambing dengan ras jawa randu dengan Body Condition Score(BCS) 2,5-3 (kondisi bagus). Deteksi lendir dilakukan pada masing kelompok perlakuan dan diberi nilai (score). Setelah terdeteksi estrus, kelompok 2 dan 3 dilakukan inseminasi buatan (IB) sedangkan kelompok 1 kawin alami dengan pejantan. Data pengamatan estrus analisis secara deskriptif sedangkan data pengamatan lendir dianalisis menggunak Chie-Square. Koleksi serum darah untuk pemeriksaan kadar estrogen diambil pada hari ke-0, 3, 12, dan 15 siklus untuk mendapatkan gambaran kadar estrogen. Hasil deteksi estrus berdasarkan pengamatan lendir diketahui terdapat perbedaan signifikan diantara kelompok (P < 0,05). Pada hari ke-0 nilai profil hormon estrogen 36,14 pg/ml, tampilan gambar alat RVE menunjukkan lendir jernih bening dan terlihat banyak disaluran serviks sampai ke vulva. Hari ke-3 profil hormon estrogen 11,13 pg/ml, terlihat leleran pekat dan sedikit keruh dan hanya terlihat di sekitaran serviks. Hari ke-12 tampilan profil hormon estrogen 8,74 pg/ml terlihat lendir menjadi pekat keruh dan hanya terdapat di sekitar serviks. Hari ke-15 dengan tampilan hormon estrogen 15,82 pg/ml terlihat leleran bening dan hanya di sekitaran serviks. Disimpulkan bahwa penggunaan alat metode baru RVE memberikan pengaruh terhadap deteksi gejala estrus yaitu mampu mendeteksi lendir berdasarkan masing-masing fase siklus berahi.
Splayed Leg in Birds: Diagnosis, Therapy, and Prevention
Authors: Permana Rief Ghulam Satriya , Indarjulianto Soedarmanto , Yanuartono Yanuartono , Nareswari Anggitya , Puspitadesy Shafa Adea
Published: January 2024

Splayed leg is a condition where the legs are stretched outwards or sideways from their normal position under the body which is often suffered by young birds. This disorder is usually left untreated, because it is considered as a permanent disability condition that cannot be treated without examining the cause. Some of the splayed legs in chicks can be improved by treating both their legs in the correct position. Early diagnosis of splayed leg and continued appropriate therapy is needed so that the condition of the foot can be restored to normal. Incorrect diagnosis and therapy will cause the bird's feet to become permanently disabled, so the bird will suffer for the rest of its life. The diagnosis and treatment of splayed leg cases have been developed with varying results. The purpose of this review is to evaluate the diagnosis, therapy, and prevention of the occurrence of splayed legs in birds, which can be used as a reference to improve bird welfare.
Developing Workers’ Sports Engagement in Northern Vietnam’s Industrial Zones
Authors: Chau TO Thi Viet
Published: January 2024

This article extensively analyzes workers’ sports participation in Northern Vietnam’s industrial zones, shedding light on the modern labor landscape. It underscores the importance of achieving work-life balance, where sports contribute to physical well-being, stress management, and positive workplace relationships. Additionally, the article addresses challenges like work-related stress, time management, and sports infrastructure investment. It emphasizes the roles of labor unions and businesses in promoting sports and employee well-being through facilities, events, and encouragement. This article initiates discussions on sports’ significance in workers’ lives, aiming to improve the work environment and overall quality of life.
Application of Passive Techniques to Achieve Thermal Comfort and Minimize Energy Consumption: A case of Office Building in Composite Climate, India
Authors: Yadav Ar. Pradeep Kumar
Published: January 2024

Abstract: Approximately 5% of India’s total construction currently embraces sustainable design, indicating significant potential in the Indian market. The key to successful building design lies in the integration of both passive & active techniques. Emphasizing passive strategies are essential due to their cost-effectiveness & superior efficiency compared to active methods. For truly achieving sustainability it is imperative to prioritize passive strategies tailored to the local climate. Active techniques should function as supplementary elements rather than overshadowing passive approaches. The study concentrates on comprehending passive design strategies specific to India’s composite climate by analyzing case studies of various office buildings. The investigation delves into passive strategies such as orientation, fenestration, shading devices, earth touch, roof gardens, water features & landscaping. The proper use of passive techniques promotes energy saving.
Malware Detection of Portable Executable Using Machine Learning and Neural Networks
Authors: Patil Jeet
Published: January 2024

Abstract: Among the more well-known types of automatic detection technology, malware detection includes detection and protection methods against viruses caused by viruses, worms, Trojan horses, spyware, and various types of malicious code. Failure to find a malware program at its inception leaves a space where it will send a significant threat and value to online security not only for individuals, organizations but also the community and the nation. And it seems that antivirus software may fail to detect viruses if it is not updated on a website with an anti-virus engine. The great struggle is to find a new virus because when it encounters new malware behavior, it takes a series of steps based on established law. If the rule of law determines thatthe new behavior is safe the virus remains undetected.
EFFECT OF GIVING PINEAPLLE JUICE (Ananas Comasus L.Merr) On Quality Of Duck Meat
Authors: Wijinindyah Ayutha , Runi  , Wulandari Lies Tiarini
Published: January 2024

Duck meat is a source of animal protein. Duck meat is widely used in various food preparations. The aim of this research was to determine the effect of giving pineapple juice on the physical and chemical quality of duck meat. The experimental design used complete randomization with four treatments and three replications. The treatments applied were : P0 : duck meat (without the additional of pineapple juice), P1 : duck meat + 25% pineapple juice, P2 : duck meat + 50% pineapple juice, P3 : duck meat + 75% pineapple juice. The data obtained was analysed using analysis of variance (ANOVA) and continued with wether three was a real influence. The variables observed include physical (pH) and chemical quality (water content, protein content and fat content). The result showed that giving pineapple juice to duck meat had a significant effect (P<0,05) on the quality of pH and water content, but thre was no significant difference (P>0,05) on protein and fat content of duck meat. Providing pineapple juice up to 50% can reduce the pH and water content, while up to 75% it has no effect on the protein and fat of duck meat.
Responsabilidade social corporativa no ramo da agricultura sustentável
Authors: Kasper Lidiane , Batista Boeno Peno Nogueira Tatiane , Prochnow Darlan Ariel , Sausen Jorge Oneide , Thesing Nelson José , Paveglio Vieira Euselia
Published: January 2024

A prática da responsabilidade social é uma temática em evidência, um indicativo que impõe novos desafios na gestão empresarial, pela qual as empresas são impulsionadas a adotar uma nova postura relacionada às questões ligadas à ética e à qualidade das relações com seus stakeholders. Assim, o presente artigo busca analisar as práticas de Responsabilidade Social Corporativa e o respectivo processo de comunicação destas ações por parte de uma empresa do ramo agrícola, localizada na região noroeste do estado do Rio Grande do Sul, à luz da primeira dimensão das categorias do modelo tridimensional de Carroll (1979), o qual contempla as responsabilidades econômica, legal, ética e discricionária. Para responder a essa inquietação, foi realizada uma pesquisa de campo embasada em um roteiro de perguntas estruturadas, com a finalidade de coletar informações sobre essas práticas e seu processo de comunicação. Os resultados apontam que a empresa pratica a responsabilidade social corporativa, contemplando as exigências econômicas, legais, éticas e discricionárias. Já em relação ao processo de comunicação, embora ainda incipiente, a empresa reconhece sua importância para disseminação das ações realizadas de modo que vem investindo na ampliação de sua divulgação.