bluuebunny/crossref_metadata_2025 huggingface dataset:
Terrestrial biome distribution in the Late Neogene inferred from a black carbon record in the northeastern equatorial Pacific
Authors: Kim Donghyun , Lee Yong Il , Hyeong Kiseong , Yoo Chan Min
Published: September 2016

The appearance and expansion of C4plants in the Late Cenozoic was a dramatic example of terrestrial ecological change. The fire hypothesis, which suggests fire as a major cause of C4grassland is gaining support, yet a more detailed relationship between fire and vegetation-type change remains unresolved. We report the content and stable carbon isotope record of black carbon (BC) in a sediment core retrieved from the northeastern equatorial Pacific that covers the past 14.3 million years. The content record of BC suggests the development process of a flammable ecosystem. The stable carbon isotope record of BC reveals the existence of the Late Miocene C4expansion, the ‘C4maximum period of burned biomass’ during the Pliocene to Early Pleistocene, and the collapse of the C4in the Late Pleistocene. Records showing the initial expansion of C4plants after large fire support the role of fire as a destructive agent of C3-dominated forest, yet the weak relationships between fire and vegetation after initial expansion suggest that environmental advantages for C4plants were necessary to maintain the development of C4plants during the late Neogene. Among the various environmental factors, aridity is likely most influential in C4expansion.
Site-specific fluorescent labeling to visualize membrane translocation of a myristoyl switch protein
Authors: Yang Sung-Tae , Lim Sung In , Kiessling Volker , Kwon Inchan , Tamm Lukas K.
Published: September 2016

Fluorescence approaches have been widely used for elucidating the dynamics of protein-membrane interactions in cells and model systems. However, non-specific multi-site fluorescent labeling often results in a loss of native structure and function, and single cysteine labeling is not feasible when native cysteines are required to support a protein’s folding or catalytic activity. Here, we develop a method using genetic incorporation of non-natural amino acids and bio-orthogonal chemistry to site-specifically label with a single fluorescent small molecule or protein the myristoyl-switch protein recoverin, which is involved in rhodopsin-mediated signaling in mammalian visual sensory neurons. We demonstrate reversible Ca2+-responsive translocation of labeled recoverin to membranes and show that recoverin favors membranes with negative curvature and high lipid fluidity in complex heterogeneous membranes, which confers spatio-temporal control over down-stream signaling events. The site-specific orthogonal labeling technique is promising for structural, dynamical, and functional studies of many lipid-anchored membrane protein switches.
Evaluating the time trends in prevalence of exomphalos in 14 cities of Liaoning province, 2006 to 2015
Authors: Gong Ting-Ting , Wu Qi-Jun , Chen Yan-Ling , Jiang Cheng-Zhi , Li Jing , Li Li-Li , Liu Cai-Xia , Li Da , Zhou Chen , Huang Yan-Hong
Published: September 2016

To evaluate time trends of exomphalos prevalence using a large population-based study with cases identified by the Liaoning Birth Defects Registry including 14 cities over the course of a 10-year period. Exomphalos prevalence, percent change, annual percent change (APC), and contribution rates of each city were calculated. Additionally, epidemiological characteristics of this malformation were described. We observed 516 cases of exomphalos among 3,248,954 live births. Birth prevalence of exomphalos was 1.59 per 10,000 live births with non-significant change during the observational period (APC = −1.19%, P = 0.48). However, significantly decreasing trends were noticed in three cities: Fushun (APC = −9.15%, P = 0.03), Benxi (APC = −11.49%, P = 0.05), and Yingkou (APC = −16.47%, P = 0.04), contributing 62.77% of the decreasing trend of overall prevalence. The mean maternal age, gestational age, and birth weight was 28.4 years (standard deviation [SD], 6.1 years), 25.6 weeks (SD, 8.6 weeks), and 1236.2 gram (SD, 1164.4 gram). For time of diagnosis, 79.8% (n = 412) cases were diagnosed during pregnancy. In summary, the prevalence of exomphalos in Liaoning province did not change remarkably during 2006 to 2015. Future studies are warranted to investigate the risk factors and create prevention strategies for this disease.
Detecting Thermal Cloaks via Transient Effects
Authors: Sklan Sophia R. , Bai Xue , Li Baowen , Zhang Xiang
Published: September 2016

Recent research on the development of a thermal cloak has concentrated on engineering an inhomogeneous thermal conductivity and an approximate, homogeneous volumetric heat capacity. While the perfect cloak of inhomogeneous κ and inhomogeneous ρcp is known to be exact (no signals scattering and only mean values penetrating to the cloak’s interior), the sensitivity of diffusive cloaks to defects and approximations has not been analyzed. We analytically demonstrate that these approximate cloaks are detectable. Although they work as perfect cloaks in the steady-state, their transient (time-dependent) response is imperfect and a small amount of heat is scattered. This is sufficient to determine the presence of a cloak and any heat source it contains, but the material composition hidden within the cloak is not detectable in practice. To demonstrate the feasibility of this technique, we constructed a cloak with similar approximation and directly detected its presence using these transient temperature deviations outside the cloak. Due to limitations in the range of experimentally accessible volumetric specific heats, our detection scheme should allow us to find any realizable cloak, assuming a sufficiently large temperature difference.
Influence of single and binary doping of strontium and lithium on in vivo biological properties of bioactive glass scaffolds
Authors: Khan Pintu Kumar , Mahato Arnab , Kundu Biswanath , Nandi Samit K. , Mukherjee Prasenjit , Datta Someswar , Sarkar Soumya , Mukherjee Jayanta , Nath Shalini , Balla Vamsi K. , Mandal Chitra
Published: September 2016

Effects of strontium and lithium ion doping on the biological properties of bioactive glass (BAG) porous scaffolds have been checked in vitro and in vivo. BAG scaffolds were prepared by conventional glass melting route and subsequently, scaffolds were produced by evaporation of fugitive pore formers. After thorough physico-chemical and in vitro cell characterization, scaffolds were used for pre-clinical study. Soft and hard tissue formation in a rabbit femoral defect model after 2 and 4 months, were assessed using different tools. Histological observations showed excellent osseous tissue formation in Sr and Li + Sr scaffolds and moderate bone regeneration in Li scaffolds. Fluorochrome labeling studies showed wide regions of new bone formation in Sr and Li + Sr doped samples as compared to Li doped samples. SEM revealed abundant collagenous network and minimal or no interfacial gap between bone and implant in Sr and Li + Sr doped samples compared to Li doped samples. Micro CT of Li + Sr samples showed highest degree of peripheral cancellous tissue formation on periphery and cortical tissues inside implanted samples and vascularity among four compositions. Our findings suggest that addition of Sr and/or Li alters physico-chemical properties of BAG and promotes early stage in vivo osseointegration and bone remodeling that may offer new insight in bone tissue engineering.
3D Holographic Observatory for Long-term Monitoring of Complex Behaviors in Drosophila
Authors: Kumar S. Santosh , Sun Yaning , Zou Sige , Hong Jiarong
Published: September 2016

Drosophila is an excellent model organism towards understanding the cognitive function, aging and neurodegeneration in humans. The effects of aging and other long-term dynamics on the behavior serve as important biomarkers in identifying such changes to the brain. In this regard, we are presenting a new imaging technique for lifetime monitoring of Drosophila in 3D at spatial and temporal resolutions capable of resolving the motion of limbs and wings using holographic principles. The developed system is capable of monitoring and extracting various behavioral parameters, such as ethograms and spatial distributions, from a group of flies simultaneously. This technique can image complicated leg and wing motions of flies at a resolution, which allows capturing specific landing responses from the same data set. Overall, this system provides a unique opportunity for high throughput screenings of behavioral changes in 3D over a long term in Drosophila.
Structural insights into Parkin substrate lysine targeting from minimal Miro substrates
Authors: Klosowiak Julian L. , Park Sungjin , Smith Kyle P. , French Michael E. , Focia Pamela J. , Freymann Douglas M. , Rice Sarah E.
Published: September 2016

Hereditary Parkinson’s disease is commonly caused by mutations in the protein kinase PINK1 or the E3 ubiquitin ligase Parkin, which function together to eliminate damaged mitochondria. PINK1 phosphorylates both Parkin and ubiquitin to stimulate ubiquitination of dozens of proteins on the surface of the outer mitochondrial membrane. However, the mechanisms by which Parkin recognizes specific proteins for modification remain largely unexplored. Here, we show that the C-terminal GTPase (cGTPase) of the Parkin primary substrate human Miro is necessary and sufficient for efficient ubiquitination. We present several new X-ray crystal structures of both human Miro1 and Miro2 that reveal substrate recognition and ubiquitin transfer to be specific to particular protein domains and lysine residues. We also provide evidence that Parkin substrate recognition is functionally separate from substrate modification. Finally, we show that prioritization for modification of a specific lysine sidechain of the cGTPase (K572) within human Miro1 is dependent on both its location and chemical microenvironment. Activation of Parkin by phosphorylation or by binding of pUb is required for prioritization of K572 for modification, suggesting that Parkin activation and acquisition of substrate specificity are coupled.
A Non-catalytic Deep Desulphurization Process using Hydrodynamic Cavitation
Authors: Suryawanshi Nalinee B. , Bhandari Vinay M. , Sorokhaibam Laxmi Gayatri , Ranade Vivek V.
Published: September 2016

A novel approach is developed for desulphurization of fuels or organics without use of catalyst. In this process, organic and aqueous phases are mixed in a predefined manner under ambient conditions and passed through a cavitating device. Vapor cavities formed in the cavitating device are then collapsed which generate (in-situ) oxidizing species which react with the sulphur moiety resulting in the removal of sulphur from the organic phase. In this work, vortex diode was used as a cavitating device. Three organic solvents (n-octane, toluene and n-octanol) containing known amount of a model sulphur compound (thiophene) up to initial concentrations of 500 ppm were used to verify the proposed method. A very high removal of sulphur content to the extent of 100% was demonstrated. The nature of organic phase and the ratio of aqueous to organic phase were found to be the most important process parameters. The results were also verified and substantiated using commercial diesel as a solvent. The developed process has great potential for deep of various organics, in general, and for transportation fuels, in particular.
Molecular archeological evidence in support of the repeated loss of a papillomavirus gene
Authors: Van Doorslaer Koenraad , McBride Alison A.
Published: September 2016

It is becoming clear that, in addition to gene gain, the loss of genes may be an important evolutionary mechanism for many organisms. However, gene loss is often associated with an increased mutation rate, thus quickly erasing evidence from the genome. The analysis of evolutionarily related sequences can provide empirical evidence for gene loss events. This paper analyzes the sequences of over 300 genetically distinct papillomaviruses and provides evidence for a role of gene loss during the evolution of certain papillomavirus genomes. Phylogenetic analysis suggests that the viral E6 gene was lost at least twice. Despite belonging to distant papillomaviral genera, these viruses lacking a canonical E6 protein may potentially encode a highly hydrophobic protein from an overlapping open reading frame, which we designate E10. Evolutionary pressure working on this alternative frame, may explain why, despite having lost the E6 open reading frame between 20 and 60 million years ago, evidence of an E6-like protein is conserved.
Diversity of bacterial dimethylsulfoniopropionate degradation genes in surface seawater of Arctic Kongsfjorden
Authors: Zeng Yin-Xin , Qiao Zong-Yun , Yu Yong , Li Hui-Rong , Luo Wei
Published: September 2016

Dimethylsulfoniopropionate (DMSP), which is the major source of organic sulfur in the world’s oceans, plays a significant role in the global sulfur cycle. This compound is rapidly degraded by marine bacteria either by cleavage to dimethylsulfide (DMS) or demethylation to 3-methylmercaptopropionate (MMPA). The diversity of genes encoding bacterial demethylation (dmdA) and DMS production (dddL and dddP) were measured in Arctic Kongsfjorden. Both dmdA and dddL genes were detected in all stations along a transect from the outer to the inner fjord, while dddP gene was only found in the outer and middle parts of the fjord. The dmdA gene was completely confined to the Roseobacter clade, while the dddL gene was confined to the genus Sulfitobacter. Although the dddP gene pool was also dominated by homologs from the Roseobacter clade, there were a few dddP genes showing close relationships to both Alphaproteobacter and Gammaproteobacter. The results of this study suggest that the Roseobacter clade may play an important role in DMSP catabolism via both demethylation and cleavage pathways in surface waters of Kongsfjorden during summer.
Secondhand Smoke is Associated with Hearing Threshold Shifts in Obese Adults
Authors: Lin Yuan-Yung , Wu Li-Wei , Kao Tung-Wei , Wu Chen-Jung , Yang Hui-Fang , Peng Tao-Chun , Lin Yu-Jen , Chen Wei-Liang
Published: September 2016

Hearing loss resulted from multiple intrinsic and extrinsic factors. Secondhand smoke (SHS) and obesity had been reported to be related to hearing loss. This study explored the possible associations of SHS and obesity with the hearing threshold. The relations between SHS and the hearing threshold in subjects from three different body mass index classes were analyzed. Our study included data from 1,961 subjects aged 20–69 years that were obtained from the National Health and Nutrition Examination Survey for the years 1999–2004. After adjusting for potential confounding factors, the subjects with the higher tertiles of serum cotinine levels tended to have higher hearing thresholds than those with the lowest tertile of serum cotinine levels (for both trends, p < 0.05). Notably, the obese subjects with the higher tertiles of serum cotinine levels had significantly higher hearing thresholds for high frequencies and low frequencies than those with the lowest tertile of serum cotinine levels (for both trends, p < 0.05). Our study showed a significant positive association between SHS exposure and hearing thresholds in the adult population, especially in obese individuals. Based on our findings, avoiding exposure to SHS, especially in obese adults, may decrease the risk of hearing loss.
Impact of clinical context on acute kidney injury biomarker performances: differences between neutrophil gelatinase-associated lipocalin and L-type fatty acid-binding protein
Authors: Asada Toshifumi , Isshiki Rei , Hayase Naoki , Sumida Maki , Inokuchi Ryota , Noiri Eisei , Nangaku Masaomi , Yahagi Naoki , Doi Kent
Published: September 2016

Application of acute kidney injury (AKI) biomarkers with consideration of nonrenal conditions and systemic severity has not been sufficiently determined. Herein, urinary neutrophil gelatinase-associated lipocalin (NGAL), L-type fatty acid-binding protein (L-FABP) and nonrenal disorders, including inflammation, hypoperfusion and liver dysfunction, were evaluated in 249 critically ill patients treated at our intensive care unit. Distinct characteristics of NGAL and L-FABP were revealed using principal component analysis: NGAL showed linear correlations with inflammatory markers (white blood cell count and C-reactive protein), whereas L-FABP showed linear correlations with hypoperfusion and hepatic injury markers (lactate, liver transaminases and bilirubin). We thus developed a new algorithm by combining urinary NGAL and L-FABP with stratification by the Acute Physiology and Chronic Health Evaluation score, presence of sepsis and blood lactate levels to improve their AKI predictive performance, which showed a significantly better area under the receiver operating characteristic curve [AUC-ROC 0.940; 95% confidential interval (CI) 0.793–0.985] than that under NGAL alone (AUC-ROC 0.858, 95% CI 0.741–0.927, P = 0.03) or L-FABP alone (AUC-ROC 0.837, 95% CI 0.697–0.920, P = 0.007) and indicated that nonrenal conditions and systemic severity should be considered for improved AKI prediction by NGAL and L-FABP as biomarkers.
Inorganic perovskite photocatalysts for solar energy utilization
Authors: Zhang Guan , Liu Gang , Wang Lianzhou , Irvine John T. S.
Published: September 2016

This review specifically summarizes the recent development of perovskite photocatalysts and their applications in water splitting and environmental remediation.
Development of operational protocols for the analysis of primary and secondary fingermark lifts by MALDI-MS imaging
Authors: Bradshaw Robert , Denison Neil , Francese Simona
Published: September 2016

Eight years of intensive research have demonstrated that Matrix Assisted Laser Desorption Ionisation-Mass Spectrometry Profiling and Imaging (MALDI-MSP and MSI) are powerful tools to gather intelligence around a suspect lifestyle, directly from the identifying ridges of a latent fingermark.
A fast response and red emission probe for mammalian thioredoxin reductase
Authors: Ma Huilong , Zhang Junmin , Zhang Zhenzhe , Liu Yaping , Fang Jianguo
Published: September 2016

The first red emission probe, TRFS-red, for thioredoxin reductase was reported with improved response rate and sensitivity.
The complex behavior of the Pd7 cluster supported on TiO2(110) during CO oxidation: adsorbate-driven promoting effect
Authors: An Wei , Liu Ping
Published: September 2016

The CO saturation-driven 3D to 2D structural transformation of the Pd7 cluster supported on TiO2(110) promotes CO oxidation activity via bifunctional synergy of interfacial sites.
Prediction of proton affinities of organic molecules using the any-particle molecular-orbital second-order proton propagator approach
Authors: Pedraza-González Laura , Romero Jonathan , Alí-Torres Jorge , Reyes Andrés
Published: September 2016

We assess the performance of the recently developed any-particle molecular-orbital second-order proton propagator. Our results show that this method provides quantitative predictions of gas phase proton affinities for a wide range of organic molecules.
Demethylation of vanillic acid by recombinant LigM in a one-pot cofactor regeneration system
Authors: Rosini Elena , D'Arrigo Paola , Pollegioni Loredano
Published: September 2016

Recombinant LigM fromSphingobiumSYK-6 and plant methionine synthase MetE enzyme efficiently convert vanillic acid into PCA with cofactor recycling.
Ambiguous electrocatalytic CO2 reduction behaviour of a nickel bis(aldimino)pyridine pincer complex
Authors: Narayanan Remya , McKinnon Meaghan , Reed Blake R. , Ngo Ken T. , Groysman Stanislav , Rochford Jonathan
Published: September 2016

The electrochemical properties of two Ni(NNN)X2 pincer complexes are reported where X = Cl or Br and NNN is N,N′-(2,6-diisopropylphenyl)bis-aldiminopyridine.
Bilayer structured supramolecular light harvesting arrays based on zinc porphyrin coordination polymers for enhanced photocurrent generation in dye sensitized solar cells
Authors: Zhang Jun-Xiang , Wu Yu , Liu Jia-Cheng , Li Ren-Zhi
Published: September 2016

Coordination polymers based on an acylhydrazone zinc porphyrin were synthesized and applied in dye sensitized solar cells for enhanced photocurrent generation.
Chemical probes and inhibitors of bromodomains outside the BET family
Authors: Moustakim Moses , Clark Peter G. K. , Hay Duncan A. , Dixon Darren J. , Brennan Paul E.
Published: September 2016

Significant progress has been made in discovering inhibitors and chemical probes of bromodomains, epigenetic readers of lysine acetylation.
Correction: Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the heat shock factor 1 (HSF1) stress pathway and CDK9. See DOI: 10.1039/c6md00159a
Authors: Rye Carl S. , Chessum Nicola E. A. , Lamont Scott , Pike Kurt G. , Faulder Paul , Demeritt Julie , Kemmitt Paul , Tucker Julie , Zani Lorenzo , Cheeseman Matthew D. , Isaac Rosie , Goodwin Louise , Boros Joanna , Raynaud Florence , Hayes Angela , Henley Alan T. , de Billy Emmanuel , Lynch Christopher J. , Sharp Swee Y. , te Poele Robert , Fee Lisa O’ , Foote Kevin M. , Green Stephen , Workman Paul , Jones Keith
Published: September 2016

Correction for ‘Discovery of 4,6-disubstituted pyrimidines as potent inhibitors of the heat shock factor 1 (HSF1) stress pathway and CDK9’ by Carl S. Rye et al., Med. Chem. Commun., 2016, 7, 1580–1586.
Coumarin phenylsemicarbazones: sensitive colorimetric and fluorescent “turn-on” chemosensors for low-level water content in aprotic organic solvents
Authors: Cigáň Marek , Gašpar Jan , Gáplovská Katarína , Holekšiová Jana , Jakusová Klaudia , Donovalová Jana , Garaj Vladimír , Stankovičová Henrieta
Published: September 2016

Highly sensitive two-component colorimetric and fluorescent “turn-on” chemosensors for water detection in aprotic organic solvents.
Radiation damage to single stranded oligonucleotide trimers labelled with 5-iodopyrimidines
Authors: Westphal Kinga , Skotnicki Konrad , Bobrowski Krzysztof , Rak Janusz
Published: September 2016

DNA labelled with 5-iodo-2′-deoxyuridne undergoes twice as much damage induced by solvated electrons compared to that observed in DNA containing 5-bromo-2′-deoxyuridine.
Recent progress towards gold-catalyzed synthesis of N-containing tricyclic compounds based on ynamides
Authors: Pan Fei , Shu Chao , Ye Long-Wu
Published: September 2016

The recent advances in the gold-catalyzed construction of N-containing tricycles based on ynamides are reviewed by highlighting their specificity and applicability, and the mechanistic rationale.
Iodine uptake and enhanced electrical conductivity in a porous coordination polymer based on cucurbit[6]uril
Authors: Lin Jing-Xiang , Liang Jun , Feng Ji-Fei , Karadeniz Bahar , Lü Jian , Cao Rong
Published: September 2016

Iodine uptake and enhanced electrical conductivity have been observed in a solid material built by cucurbit[6]uril units and an iodide matrix.
Triphenylamine-based donor–π–acceptor organic phosphors: synthesis, characterization and theoretical study
Authors: Kajjam Aravind Babu , Giri Santanb , V. Sivakumar
Published: September 2016

We have designed and synthesized donor (D) and acceptor (A) phosphors [D and A refer to the electron-donating and electron-withdrawing moieties, respectively] as yellow-emitting organic phosphors.
Boosting the supercapacitive properties of polypyrrole with chitosan and hybrid silver nanoparticles/nanoclusters
Authors: Gan John Kevin , Lim Yee Seng , Huang Nay Ming , Lim Hong Ngee
Published: September 2016

We report a one-step route to hierarchical polypyrrole/chitosan decorated with hybrid Ag nanoparticles/nanoclusters (Ag@PPy/CS) via electrodeposition.
Functionalized and reusable polyethylene fibres for Au(iii) extraction from aqueous solution with high adsorption capacity and selectivity
Authors: Pang Li-juan , Li Rong , Gao Qian-hong , Hu Jiang-tao , Xing Zhe , Zhang Ming-xing , Wang Mou-hua , Wu Guo-Zhong
Published: September 2016

Functional UHMWPE fibres, used for efficient and selective Au(iii) adsorption from aqueous solutions, were successfully synthesized by a radiation grafting method.
Readily biodegradable and low-toxic biocompatible ionic liquids for cellulose processing
Authors: Markiewicz Marta , Maszkowska Joanna , Nardello-Rataj Véronique , Stolte Stefan
Published: September 2016

Ecotoxicity and biodegradability of ILs intended for cellulose processing were tested. Betaine-ester levulinate exhibits low environmental hazard potential (full degradability, low toxicity). Other ILs were partially degradable and moderately toxic.
Phosphonium ionic liquids as greener electrolytes for poly(vinyl chloride)-based ionic conducting polymers
Authors: Dias A. M. A. , Marceneiro S. , Johansen H. D. , Barsan M. M. , Brett C. M. A. , de Sousa H. C.
Published: September 2016

Ionic liquid (IL) based ion-conducting polymers were prepared by loading poly(vinyl chloride) (PVC) with phosphonium ILs and diisononyl phthalate. IL ionicity and IL–PVC miscibility play a major role in decreasing the electrical resistivity of PVC.
Synthesis of Zn-doped In2O3nano sphere architectures as a triethylamine gas sensor and photocatalytic properties
Authors: Sun Xin , Liu Xiaojing , Deng Xiaolong , Xu Xijin
Published: September 2016

Zn-doped In2O3nano spheres (ZIO NSs) were synthesized by calcining the precipitates prepared through a facile one-step hydrothermal synthesis method.
Spatial control of direct chemical vapor deposition of graphene on silicon dioxide by directional copper dewetting
Authors: van den Beld Wesley T. E. , van den Berg Albert , Eijkel Jan C. T.
Published: September 2016

A non-manual, controllable and wafer-scale method for the spatial control of direct graphene synthesis onto silicon dioxide by controlled dewetting and evaporation of copper.
Accelerated microrockets with a biomimetic hydrophobic surface
Authors: Chang Xiaocong , Li Longqiu , Li Tianlong , Zhou Dekai , Zhang Guangyu
Published: September 2016

A biomimetic method was employed to accelerate the velocity and thereby to improve its propulsion efficiency of microrockets.
Iron phosphide (FeP) synthesis, and full cell lithium-ion battery study with a [Li(NiMnCo)O2] cathode
Authors: Veluri P. S. , Mitra S.
Published: September 2016

A scalable two-step strategy is utilized to synthesize iron phosphide (FeP) from iron oxide (Fe2O3).
Adsorption behavior of carboxymethyl konjac glucomannan microspheres for fluoride from aqueous solution
Authors: Wu Liping , Lin Xiaoyan , Wu Jiajie , Zhou Xingbao , Luo Xuegang
Published: September 2016

The CMKGM–La–Al is characterized by SEM, EDX, and XPS. We find that adsorption mechanism of the adsorbent involved coordination reaction and electrostatic interaction. The schematic diagram of preparation of CMKGM–La–Al is shown as above.
Green synthesis of gold nanoparticles reduced and stabilized by squaric acid and supported on cellulose fibers for the catalytic reduction of 4-nitrophenol in water
Authors: Islam Md. Tariqul , Padilla Julio E. , Dominguez Noemi , Alvarado Daisy C. , Alam Md Shah , Cooke Peter , Tecklenburg Mary M. J. , Noveron Juan C.
Published: September 2016

Gold nanoparticles reduced and stabilized by sodium squarate in water that attach to cellulose fibers and catalyse the reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP) with sodium borohydride.
Mixed surfactant modified graphene oxide nanocarriers for DOX delivery to cisplatin-resistant human ovarian carcinoma cells
Authors: Zhang Qian , Chi Huirong , Tang Mingzhi , Chen Jiabin , Li Guolin , Liu Yushi , Liu Bing
Published: September 2016

Mixed surfactant modified graphene oxide nanocarriers based on the nonideal mixed micelle theory of surfactants exhibit great potential in drug delivery.
Alginic acid oligosaccharide accelerates weaned pig growth through regulating antioxidant capacity, immunity and intestinal development
Authors: Wan Jin , Jiang Fei , Xu Qingsong , Chen Daiwen , He Jun
Published: September 2016

Alginic acid oligosaccharide (ALGO) is the lyase–lysate of alginic acid, which is a naturally occurring anionic polysaccharide isolated from the cell walls of seaweed.
Non-planar backbone structure polybenzimidazole membranes with excellent solubility, high proton conductivity, and better anti-oxidative for HT-PEMFCs
Authors: Sun Guohua , Han Kefei , Yu Jinghua , Zhu Hong , Wang Zhongming
Published: September 2016

This work introduces a bulky stereostructure monomer (BPY) to obtain a series of novel non-planar BPY-PBI-x polymers, which exhibit excellent solubility, high proton conductivity, and better anti-oxidative for HT-PEMFCs.
Diketopyrrolopyrrole or benzodithiophene-arylamine small-molecule hole transporting materials for stable perovskite solar cells
Authors: Liu Xuepeng , Kong Fantai , Tan Zhan'ao , Cheng Tai , Chen Wangchao , Yu Ting , Guo Fuling , Chen Jian , Yao Jianxi , Dai Songyuan
Published: September 2016

Two new hole transporting materials with diketopyrrolopyrrole or benzodithiophene moieties were developed for stable perovskite solar cells.
Additive effect of alkaline earth metals on ammonia decomposition reaction over Ni/Y2O3 catalysts
Authors: Okura Kaname , Okanishi Takeou , Muroyama Hiroki , Matsui Toshiaki , Eguchi Koichi
Published: September 2016

The addition of Sr/Ba species enhanced ammonia conversion of Ni/Y2O3 since these additives promoted nitrogen desorption from Ni metal.
Heterogeneous photocatalytic ozonation of ciprofloxacin using synthesized titanium dioxide nanoparticles on a montmorillonite support: parametric studies, mechanistic analysis and intermediates identification
Authors: Hassani Aydin , Khataee Alireza , Karaca Semra , Fathinia Mehrangiz
Published: September 2016

A titanium dioxide/montmorillonite (TiO2/MMT) nanocomposite was prepared as a photocatalyst by a hydrothermal method.
Covalently bonded double-charged ionic liquid on magnetic graphene oxide as a novel, efficient, magnetically separable and reusable sorbent for extraction of heavy metals from medicine capsules
Authors: Lotfi Zahra , Mousavi Hassan Zavvar , Sajjadi S. Maryam
Published: September 2016

Development of a new SPE sorbent with a chemically bonded double-charged ionic liquid on magnetic graphene oxide to solve the disadvantages of ionic liquid based SPE methods.
QM/MM calculations and MD simulations of acetolactate decarboxylase to reveal substrate R/S-acetolactate binding mode and stereoselective catalytic mechansim
Authors: Zhuang Can-Bo , Zheng Qing-Chuan
Published: September 2016

Acetolactate decarboxylase (ALDC) catalyzesR/S-acetolactate to make the same product, (R)-acetoin, with different processes.
Synthesis and thermal properties of an acetylenic monomer containing boron and silicon
Authors: Cheng Shengli , Zong Lishuai , Yuan Kuanyu , Han Jianhua , Jian Xigao , Wang Jinyan
Published: September 2016

Here we report using trimethylsilylethynyl as crosslinking groups for thermosetting polymers.
Triple-helix molecular switch-induced hybridization chain reaction amplification for developing a universal and sensitive electrochemical aptasensor
Authors: Liu Qiaoqiao , Liu Jinquan , He Dinggeng , Qing Taiping , He Xiaoxiao , Wang Kemin , Mao Yinfei
Published: September 2016

In this work, a universal and sensitive “signal-on” electrochemical aptasensor platform has been developed based on a triple-helix molecular switch (THMS)-induced hybridization chain reaction (HCR) amplification.
Tunable negative permittivity behavior of random carbon/alumina composites in the radio frequency band
Authors: Cheng Chuanbing , Fan Runhua , Qian Lei , Wang Xuai , Dong Lihua , Yin Yansheng
Published: September 2016

As carbon content increases, the composites undergo a capacitive–inductive transition, and a weakly negative permittivity behavior is observed.
A novel duplex PDMS/CrN coating with superior corrosion resistance for marine applications
Authors: Guan Xiaoyan , Wang Yongxin , Zhang Guangan , Xin Jiang , Wang Liping , Xue Qunji
Published: September 2016

A new duplex PDMS/CrN coating was developed and the corrosion resistance of the system under seawater conditions was investigated.
Selective, light-driven enzymatic dehalogenations of organic compounds
Authors: Siritanaratkul Bhavin , Islam Shams T. A. , Schubert Torsten , Kunze Cindy , Goris Tobias , Diekert Gabriele , Armstrong Fraser A.
Published: September 2016

A reductive dehalogenase (PceA) adsorbed on TiO2 nanoparticles catalyzes regiospecific transformations of chlorinated ethenes under UV irradiation.
Recent progress on stability issues of organic–inorganic hybrid lead perovskite-based solar cells
Authors: Li Dan , Liao Peizhe , Shai Xuxia , Huang Wenchao , Liu Shaungshuang , Li Hao , Shen Yan , Wang Mingkui
Published: September 2016

Over the past few years, substantial progress has been made in research on organic–inorganic halide perovskite solar cells.
New dimeric and trimeric Erythrina alkaloids from Erythrina variegata
Authors: Zhang Bing-Jie , Wu Bin , Bao Mei-Fen , Ni Ling , Cai Xiang-Hai
Published: September 2016

HPLC-guided chromatography isolation led to five new polymeric Erythrina alkaloids, erythrivarines C–G (1–5), from the flowers of Erythrina variegata.
Fabrication of complex PDMS microfluidic structures and embedded functional substrates by one-step injection moulding
Authors: Szydzik C. , Niego B. , Dalzell G. , Knoerzer M. , Ball F. , Nesbitt W. S. , Medcalf R. L. , Khoshmanesh K. , Mitchell A.
Published: September 2016

We report a novel injection moulding technique for fabrication of complex multi-layer microfluidic structures, allowing one-step robust integration of functional components with microfluidic channels and fabrication of elastomeric valves.
On the stability of surfactant-stabilised few-layer black phosphorus in aqueous media
Authors: Brent Jack R. , Ganguli Ashok K. , Kumar Vinod , Lewis David J. , McNaughter Paul D. , O'Brien Paul , Sabherwal Priyanka , Tedstone Aleksander A.
Published: September 2016

The stability of few-layer black phosphorus has been studied in aqueous media using a range of spectroscopic techniques. The material is meta-stable, degrading over time mainly to phosphoric acids.
Influence of vacancy defects and 3d transition metal adatoms on the electronic and magnetic properties of graphene
Authors: Zhou Qingxiao , Ju Weiwei , Su Xiangying , Yong Yongliang , Fu Zhibing , Wang Chaoyang , Li Xiaohong
Published: September 2016

Based on the density functional theory (DFT) method, we investigated the geometry stability, electronic and magnetic properties of vacancy-defected graphene with and without the adsorption of transition metal (TM) adatoms (V, Cr, and Mn).
Electronic tuning of self-healing fluorophores for live-cell and single-molecule imaging
Authors: Zheng Qinsi , Jockusch Steffen , Zhou Zhou , Altman Roger B. , Zhao Hong , Asher Wesley , Holsey Michael , Mathiasen Signe , Geggier Peter , Javitch Jonathan A. , Blanchard Scott C.
Published: September 2016

Mechanistic investigation of self-healing fluorophores leads to a general approach for highly photostable fluorophores across the spectrum.
Fe oxide nanoparticles/Ti-modified mesoporous silica as a photo-catalyst for efficient and selective cyclohexane conversion with O2 and solar light
Authors: Ide Y. , Iwata M. , Yagenji Y. , Tsunoji N. , Sohmiya M. , Komaguchi K. , Sano T. , Sugahara Y.
Published: September 2016

Photocatalytic partial oxidation of cyclohexane with O2 and solar light by mesoporous silica with grafted Ti coupled to Fe oxide nanoparticles.
Two-dimensional hybrid nanosheets of few layered MoSe2 on reduced graphene oxide as anodes for long-cycle-life lithium-ion batteries
Authors: Luo Zhigao , Zhou Jiang , Wang Lirong , Fang Guozhao , Pan Anqiang , Liang Shuquan
Published: September 2016

We report the synthesis of a novel 2D hybrid nanosheet constructed by few layered MoSe2 grown on reduced graphene oxide (rGO), which exhibits excellent electrochemical performance as anodes for lithium ion batteries.
Keratin-derived S/N co-doped graphene-like nanobubble and nanosheet hybrids for highly efficient oxygen reduction
Authors: Zhang Jian , Zhou Huang , Liu Xiaobo , Zhang Jie , Peng Tao , Yang Jinlong , Huang Yunhui , Mu Shichun
Published: September 2016

Novel S/N co-doped graphene-like nanobubble and nanosheet hybridized architectures were prepared. Such graphene-like hybrids exhibit a better ORR performance and fuel tolerance than commercial Pt/C catalyst in alkaline media.
Every nonlinear element from Chua's table can generate pinched hysteresis loops: generalised homothety theorem
Authors: Biolek D. , Biolek Z. , Biolkova V.
Published: September 2016

The pinched hysteresis loops drawn in the voltage–current, voltage–charge, and flux–current characteristics belong to well‐known fingerprints of the memory elements known as the memristor, memcapacitor, and meminductor. It is shown that generating such loops is in fact a natural attribute of all nonlinear elements from Chua's table, and that the hysteresis need not necessarily be a manifestation of the internal memory of the element. A generalised homothety theorem is introduced, which describes the regularities of such a hysteresis and its frequency dependence.
Flux linkage estimation based loss of excitation relay for synchronous generator
Authors: Abedini Moein , Sanaye‐Pasand Majid , Davarpanah Mahdi
Published: September 2016

Loss of excitation (LOE) event threatens both the generator and power system stability. Numerous approaches have been proposed for LOE detection, most of which use the impedance trajectory. Such methods may maloperate under system disturbances, especially power swings. This study presents a new approach for LOE detection by estimating the field flux linkage participation (FFLP) in the stator flux linkage. Intrinsically, this newly defined index mainly depends on the generator excitation system and thus highly reduces when an LOE takes place. The FFLP parameter can easily be calculated using stator voltage and current signals. All kinds of LOE events cannot be studied using most available simulation software. To cover all of them, utilising state variables, a generator model connected to a power system is implemented. Performed simulation studies demonstrate that the proposed strategy not only considerably decreases the LOE relay operation time, but also improves the LOE relay security against system disturbances. In addition, the proposed approach is experimentally evaluated on a 10 kVA synchronous generator.
Automated analysis of pedestrian walking behaviour at a signalised intersection in China
Authors: Guo Yanyong , Sayed Tarek , Zaki Mohamed H.
Published: September 2016

An analysis of pedestrian walking behavior using gait parameters is presented; it uses automated video analysis to collect pedestrian data at a signalized intersection in Nanjing, China. Two aspects of microscopic pedestrian behavior are considered: First, the walking mechanism represented by pedestrian gait parameters. Second, the non‐conforming crossing behavior of pedestrians. The effect of various pedestrian related attributes are investigated. The results show high accuracy in automatically detecting pedestrian violations, with an 85.2% correct detection rate. The walking speed and gait parameters for spatial violators are found to be significantly higher compared to non‐violators. It is also found that pedestrians who enter the crosswalk during the late stage of the green pedestrian phase often adopt higher walking speed. The gait analysis shows that males tend to have a higher walking speed, walk ratio and longer step length than females. Single pedestrians are found to have higher speed and step frequency compared to pedestrians in groups. The presence of bikes on crosswalks significantly decreases the pedestrian walking speed, step length and frequency, leading to more gait variability. Such results are useful for many future applications such as calibration of simulation models and violation detection.
Vernetzung: „Wir müssen den Hunger auf Daten im Griff behalten“
Authors: Kohrs Jens
Published: September 2016

FKT-Präsident Horst Träger sieht in der Digitalisierung große Chancen. Praxistaugliche Konzepte allerdings fehlen ihm noch.
WGKT-Tagung Technik im Krankenhaus TK 2016: Im Sog der Daten
Authors: Kohrs Jens
Published: September 2016

In Kliniken fallen heute gewaltige Datenmengen an, unzählige Auswertungen können angestoßen werden. Damit verantwortungsvoll umzugehen, ist eine der großen Herausforderungen. Bei der WGKT-Tagung in Leipzig ist Big Data deshalb das Schwerpunktthema.
IT-Strategie: „Suchen kostet Zeit, die anderswo fehlt“
Authors: Kohrs Jens
Published: September 2016

Als Keynote-Speaker der WGKT-Tagung wird Jörg Reschke die IT-Strategie des Klinikkonzerns Helios beschreiben. kma hat der Geschäftsführer Finanzen schon vorab vier Fragen beantwortet.
Krankenhaus 4.0: Vorbild Dänemark? Das „Super-Hospital“ in Aarhus
Authors: Deiters Wolfgang
Published: September 2016

Was derzeit im Uniklinikum Aarhus entsteht, dürfte auch deutsche Krankenhaustechniker aufhorchen lassen. Die Dänen machen vor, was in Sachen Digitalisierung möglich ist. Was die Konzepte der Planer so überzeugend macht und warum heimische Kliniken davon lernen können.
Anlagenwartung: Spezialpflege für die Stromversorgung
Authors: Hodde Thomas
Published: September 2016

Die Stromversorgung im Krankenhaus ist ein hochsensibler Bereich. Bei der Wartung und Instandhaltung der Anlagen setzen Klinikchefs deshalb zunehmend auf externe Servicepartner. Sie kontrollieren und reinigen die Anlagen, identifizieren potenzielle Störungen und stehen auf Abruf bereit, falls es zu Ausfällen kommt.
Generalized logarithmic scaling for high-order moments of the longitudinal velocity component explained by the random sweeping decorrelation hypothesis
Authors: Katul Gabriel G. , Banerjee Tirtha , Cava Daniela , Germano Massimo , Porporato Amilcare
Published: September 2016

Expressions for the logarithmic variations of the normalized turbulent longitudinal velocity (u2p¯+)1/p with normalized distance z/δ from a boundary for high-order (p) moments in the intermediate region of wall bounded flows characterized by thickness δ are derived. The ansatz that (u2p¯+)1/p variation in ln(z/δ) originates from a compound effect of random sweeping and -1 power-law scaling in the longitudinal velocity spectrum Eu(k) is discussed, where k is the wavenumber. Using velocity time series sampled above a uniform ice sheet, an Eu(k) ∼ k−1 scaling is confirmed for kz < 1 and kδ > 1. The data were then used to analyze assumptions required for the utility of the random sweeping decorrelation (RSD) hypothesis connecting the k−1 power-law with log-scaling in (u2p¯+)1/p. It has been found out that while the RSD hypothesis is operationally applicable to scales associated with attached eddies bounded by kz < 1 and kδ > 1, significant interactions among high-order turbulent velocity and velocity increments lead to the conclusion that the RSD hypothesis cannot be exactly valid. Its operational utility stems from the observations that some of the interaction terms among the high-order velocity and velocity increments act in opposite directions thereby canceling their additive effects in RSD.
Isotope effects in liquid water probed by transmission mode x-ray absorption spectroscopy at the oxygen K-edge
Authors: Schreck Simon , Wernet Philippe
Published: September 2016

The effects of isotope substitution in liquid water are probed by x-ray absorption spectroscopy at the O K-edge as measured in transmission mode. Confirming earlier x-ray Raman scattering experiments, the D2O spectrum is found to be blue shifted with respect to H2O, and the D2O spectrum to be less broadened. Following the earlier interpretations of UV and x-ray Raman spectra, the shift is related to the difference in ground-state zero-point energies between D2O and H2O, while the difference in broadening is related to the difference in ground-state vibrational zero-point distributions. We demonstrate that the transmission-mode measurements allow for determining the spectral shapes with unprecedented accuracy. Owing in addition to the increased spectral resolution and signal to noise ratio compared to the earlier measurements, the new data enable the stringent determination of blue shift and broadening in the O K-edge x-ray absorption spectrum of liquid water upon isotope substitution. The results are compared to UV absorption data, and it is discussed to which extent they reflect the differences in zero-point energies and vibrational zero-point distributions in the ground-states of the liquids. The influence of the shape of the final-state potential, inclusion of the Franck-Condon structure, and differences between liquid H2O and D2O resulting from different hydrogen-bond environments in the liquids are addressed. The differences between the O K-edge absorption spectra of water from our transmission-mode measurements and from the state-of-the-art x-ray Raman scattering experiments are discussed in addition. The experimentally extracted values of blue shift and broadening are proposed to serve as a test for calculations of ground-state zero-point energies and vibrational zero-point distributions in liquid H2O and D2O. This clearly motivates the need for new calculations of the O K-edge x-ray absorption spectrum of liquid water.
Perspective: On the importance of hydrodynamic interactions in the subcellular dynamics of macromolecules
Authors: Skolnick Jeffrey
Published: September 2016

An outstanding challenge in computational biophysics is the simulation of a living cell at molecular detail. Over the past several years, using Stokesian dynamics, progress has been made in simulating coarse grained molecular models of the cytoplasm. Since macromolecules comprise 20%-40% of the volume of a cell, one would expect that steric interactions dominate macromolecular diffusion. However, the reduction in cellular diffusion rates relative to infinite dilution is due, roughly equally, to steric and hydrodynamic interactions, HI, with nonspecific attractive interactions likely playing rather a minor role. HI not only serve to slow down long time diffusion rates but also cause a considerable reduction in the magnitude of the short time diffusion coefficient relative to that at infinite dilution. More importantly, the long range contribution of the Rotne-Prager-Yamakawa diffusion tensor results in temporal and spatial correlations that persist up to microseconds and for intermolecular distances on the order of protein radii. While HI slow down the bimolecular association rate in the early stages of lipid bilayer formation, they accelerate the rate of large scale assembly of lipid aggregates. This is suggestive of an important role for HI in the self-assembly kinetics of large macromolecular complexes such as tubulin. Since HI are important, questions as to whether continuum models of HI are adequate as well as improved simulation methodologies that will make simulations of more complex cellular processes practical need to be addressed. Nevertheless, the stage is set for the molecular simulations of ever more complex subcellular processes.