bluuebunny/crossref_metadata_2025 huggingface dataset:
Plant Growth Promotion and Biocontrol of Leaf Blight Caused by Nigrospora sphaerica on Passion Fruit by Endophytic Bacillus subtilis Strain GUCC4
Authors: Wang Junrong , Qin Shun , Fan Ruidong , Peng Qiang , Hu Xiaojing , Yang Liu , Liu Zengliang , Baccelli Ivan , Migheli Quirico , Berg Gabriele , Chen Xiaoyulong , Cernava Tomislav
Published: January 2023

Passion fruit (Passiflora edulis Sims) is widely cultivated in tropic and sub-tropic regions for the production of fruit, flowers, cosmetics, and for pharmacological applications. Its high economic, nutritional, and medical values elicit the market demand, and the growing areas are rapidly increasing. Leaf blight caused by Nigrospora sphaerica is a new and emerging disease of passion fruit in Guizhou, in southwest China, where the unique karst mountainous landscape and climate conditions are considered potential areas of expansion for passion fruit production. Bacillus species are the most common biocontrol and plant-growth-promotion bacteria (PGPB) resources in agricultural systems. However, little is known about the endophytic existence of Bacillus spp. in the passion fruit phyllosphere as well as their potential as biocontrol agents and PGPB. In this study, 44 endophytic strains were isolated from 15 healthy passion fruit leaves, obtained from Guangxi province, China. Through purification and molecular identification, 42 of the isolates were ascribed to Bacillus species. Their inhibitory activity against N. sphaerica was tested in vitro. Eleven endophytic Bacillus spp. strains inhibited the pathogen by >65%. All of them produced biocontrol- and plant-growth-promotion-related metabolites, including indole-3-acetic acid (IAA), protease, cellulase, phosphatase, and solubilized phosphate. Furthermore, the plant growth promotion traits of the above 11 endophytic Bacillus strains were tested on passion fruit seedlings. One isolate, coded B. subtilis GUCC4, significantly increased passion fruit stem diameter, plant height, leaf length, leaf surface, fresh weight, and dry weight. In addition, B. subtilis GUCC4 reduced the proline content, which indicated its potential to positively regulate passion fruit biochemical properties and resulted in plant growth promotion effects. Finally, the biocontrol efficiencies of B. subtilis GUCC4 against N. sphaerica were determined in vivo under greenhouse conditions. Similarly to the fungicide mancozeb and to a commercial B. subtilis-based biofungicide, B. subtilis GUCC4 significantly reduced disease severity. These results suggest that B. subtilis GUCC4 has great potential as a biological control agent and as PGPB on passion fruit.
Price Discovery Mechanism and Volatility Spillover between National Agriculture Market and National Commodity and Derivatives Exchange: The Study of the Indian Agricultural Commodity Market
Authors: Garg Mohit , Singhal Shelly , Sood Kiran , Rupeika-Apoga Ramona , Grima Simon
Published: January 2023

Agricultural commodity markets are critical to the global economy. This study investigates the price discovery mechanism, lead-lag relationship, and volatility spillover between spot prices on the National Agriculture Market (E-NAM) and futures and spot prices on the National Commodity and Derivative Exchange (NCDEX) in the Indian agricultural commodity market. The Johansen Cointegration, Vector Error Correction (VEC), Granger causality tests, and bivariate GARCH models were applied to daily data from April 2016 to December 2020 for twelve agricultural commodities traded on the E-NAM and NCDEX. We discovered the long-run relationship using the Johansen Cointegration test and concluded that the NCDEX spot and futures market is dominant in the price discovery mechanism, and the NCDEX futures and spot markets lead the E-NAM spot prices having a unidirectional or bidirectional relationship. Furthermore, the bivariate GARCH model suggested a volatility spillover from E-NAM spot prices to NCDEX futures and spot markets for most commodities, except for bajra, barley, and jeera, which have no volatility spillover. The study’s findings have important implications for various stakeholders, including policymakers, farmers, investors, traders, and others who want to reduce price risks by using information from the E-NAM market’s spot prices.
Ryukyuan Perspectives for Language Reclamation
Authors: Heinrich Patrick
Published: January 2023

If languages are naturally transmitted in a stable self-regulatory society (Fishman 1991, p [...]
A Unifying Principle in the Theory of Modular Relations
Authors: Liu Guodong , Chakraborty Kalyan , Kanemitsu Shigeru
Published: January 2023

The Voronoĭ summation formula is known to be equivalent to the functional equation for the square of the Riemann zeta function in case the function in question is the Mellin tranform of a suitable function. There are some other famous summation formulas which are treated as independent of the modular relation. In this paper, we shall establish a far-reaching principle which furnishes the following. Given a zeta function Z(s) satisfying a suitable functional equation, one can generalize it to Zf(s) in the form of an integral involving the Mellin transform F(s) of a certain suitable function f(x) and process it further as Z˜f(s). Under the condition that F(s) is expressed as an integral, and the order of two integrals is interchangeable, one can obtain a closed form for Z˜f(s). Ample examples are given: the Lipschitz summation formula, Koshlyakov’s generalized Dedekind zeta function and the Plana summation formula. In the final section, we shall elucidate Hamburger’s results in light of RHBM correspondence (i.e., through Fourier–Whittaker expansion).
Is Surgery in Autoimmune Pancreatitis Always a Failure?
Authors: Zavrtanik Hana , Tomažič Aleš
Published: January 2023

Autoimmune pancreatitis is a rare form of chronic pancreatitis of presumed autoimmune etiology. Due to significant overlap in clinical and imaging characteristics, misdiagnosis as a pancreatic malignancy is common. As a result, a significant number of patients undergo a major pancreatic resection, associated with considerable morbidity, for a disease process that generally responds well to corticosteroid therapy. In the past ten years, important advances have been made in understanding the disease. Several diagnostic criteria have been developed to aid in diagnosis. Despite this, pancreatic resection may still be required in a subset of patients to reliably exclude pancreatic malignancy and establish a definite diagnosis of autoimmune pancreatitis. This article aimed to define the role of surgery in autoimmune pancreatitis, if any. For this purpose, published case series of patients with a diagnosis of autoimmune pancreatitis, based on the histopathological examination of surgical specimens, were reviewed and patients’ clinical, radiological and serological details were assessed. At the end, histopathologic examinations of patients who underwent pancreatic resection at our department in the last 10 years were retrospectively reviewed in order to identify patients with autoimmune pancreatitis and assess their clinical characteristics.
Civic Solidarity and Public Health Ethics
Authors: Farrés Juste Oriol
Published: January 2023

Is solidarity in bioethics or public health ethics necessary? If so, why? Is there room for a principle of obligatory solidarity in bioethics or in public health ethics? In the first part of this paper, I assess the meaning of the value of solidarity in ethics. In the second part, I propose insights into the republican interpretation of solidarity, or, more correctly, “civic” solidarity. This is crucial to be able to distinguish between different sources of, and justifications for, solidarity, some legitimate and some not legitimate. In the third part of the paper, I apply the republican concept of civic solidarity to the field of bioethics and public health ethics. This is intended to show how civic republicanism can correct both liberal deficiencies and communitarian excesses in bioethics. Civic solidarity is essential to finding this middle way. It is a key concept, considering the challenges that we face as citizens, health professionals and patients. Finally, the paper concludes with a summary and a plan for further research in this area.
Green Solid-Phase (Micro)Extraction of Andrographolides’ from Human Plasma Samples Followed by UHPLC-DAD-QqQ-MS/MS Analysis
Authors: Kovačić Jelena , Jeličić Mario-Livio , Amidžić Klarić Daniela , Mornar Ana
Published: January 2023

Since inflammatory bowel disease is a progressive disease, optimal treatment early in the disease course is paramount. Still, the use of conventional drugs is accompanied by side effects. The herbal therapies for gastrointestinal disorders are traditionally widespread in Asia, while in Western countries have been adopted in recent years. Andrographis paniculata is a herbaceous plant used in anti-inflammatory treatment. To improve its clinical application, an analytical method with the potential to define a relationship between dose and plasma concentration of active ingredients is prerequisite. Considering the increasing demand for eco-friendly bioanalytical methods, our research aimed to implement new sample preparation technique microextraction by packed sorbent for extraction of marker compounds of A. paniculata from plasma. This green procedure using polymeric sorbent based on the poly (styrene-divinylbenzene) allowed miniaturization of sample volume (100 µL), decrease in consumption of solvents, and high recovery (92–98%). A highly selective and sensitive reversed-phase ultrahigh-performance liquid chromatography method has been developed and validated. The newest greenness assessment software AGREE calculator was used for evaluation of the method’s environmental performance. It suggests that our method conforms to the eco-friendly conditions (score 0.8). The sample preparation was identified as weak point of the bioanalytical methods which highlights the importance of microextraction.
Enteric hepatitis
Authors:   FSBI National Medical Research Center for Obstetrics, Gynecology and Perinatology named after academician V. I. Kulakov of the Ministry of Health of Russia, Klimov V. A.
Published: January 2023

Viral hepatitis is an extensive group of human diseases caused by viruses with tropism to liver damage, which leads to a liver function disorder. There are various ways of viral hepatitis transmission, but the main ones are enteral and parenteral. Hepatitis with a predominantly enteral route of transmission includes hepatitis A and E. Methods for diagnosing and treating this pathology are presented in the article.
Dynamics of morbidity rates of the Orenburg Region population
Authors:   FSBEI HE Orenburg State Medical University of the Ministry of Health of Russia, Senchenko M. A.
Published: January 2023

The morbidity of the population includes primary incidence, prevalence (cumulative incidence), and the frequency of diseases established during medical examinations. Various data are used to analyze and process information about morbidity: data on medical aid appealability, data from the results of routine medical examinations, and data from the analysis of the causes of death. In dynamics from 2015 to 2020, general morbidity of the population of the Orenburg Region was characterized by the fact that the morbidity rates of respiratory diseases still ranked first, while diseases of the circulatory organs ranked second. Diseases of the digestive system, which previously occupied the 6th ranking position, moved to the third place. The primary incidence of the population from 2015 to 2020 was characterized by the fact that the morbidity of respiratory diseases also remained in first place, while injuries, poisoning and some other consequences of external causes ranked second. Diseases of the circulatory system, which previously occupied the 5th ranking place, moved to the third place. In order to improve the health of citizens, reduce the population morbidity, improve the standard of living, increase the birth rate, decrease the death rate, raise the life expectancy of the population, and improve the environmental situation in our region, it is necessary to make decisions at the level of the legislative and executive authorities of municipalities and the subject of the Russian Federation, i.e. Orenburg Region.
African American Leaders: Guardians of Public Values—An Interview with James Joseph
Authors: Bordas Juana
Published: January 2023

Robert Greenleaf saw the rock upon which a good society would be built as people caring for and serving one another. While he noted that in previous times this was largely person-to-person, he expanded this thesis and charged large institutions with the task of building a just and loving society-one that would offer greater creative opportunities to its people. A prophetic and compassionate man, Greenleaf saw the underlying power shift being advocated for by social movements of the late twentieth century as having far-reaching implications and changes for leadership. In a prophetic and alarming statement he proposed that today's privileged might best serve by "waiting and listening until the less favored define their own priority needs and how they want to be served." Greenleaf, a White male who spent his career in corporate America, had the foresight and humility to understand that authentic leadership rises from the people and community that are to be served.As can be seen in his writings and teachings, Greenleaf's life is living proof that concepts and ideas inspire people to think and then act in new ways. The hope of this interview is to bring forth the voice of James Joseph, an exceptional African American, a servant-leader, who is "very right for the time and place" in which he lives-a synchronicity Greenleaf identified as critical to great leadership. Dr. Joseph urges Americans to re-embrace the public values on which this country was founded-values heralding common welfare, justice, and equality. Furthermore, he asserts that these values have been kept in trust by the African American community and are the foundation of the South African liberation movement. Joseph challenges Americans to shed the cloak of individualism and the current focus on personal morality, and look instead to re-establishing public values that will hold our society accountable for the welfare of all people. Public values were not a theme highlighted by Greenleaf, yet inherent in his writing is a set of intrinsic values that are the wellspring of servant leadership. In Trustees as Servants (1974), Greenleaf stated, "Perhaps the greatest threat is that we lack the mechanism of consensus, a way of making up our collective minds." It may be that the consensus Greenleaf sought can be found by taking to heart and then acting on Joseph's call to re-establish our public values, and then forging servant-leadership that supports the common welfare. A look at the dynamics of the period that gave rise to the Civil Rights movement provides a framework for understanding the influence and impact of Dr. Joseph's conceptual leadership and his call for social responsibility.
Os gêneros textuais digitais e as tecnologias digitais de informação e comunicação no ensino de língua portuguesa
Authors: Arcanjo Joel Rodrigues
Published: January 2023

Este artigo se refere a uma investigação que explorou como “Os gêneros textuais digitais e as tecnologias digitais de informação e comunicação são usados no Ensino da Língua Portuguesa, na Coordenadoria Regional de Ensino de Tonantins, no Amazonas, em 2021.  Para tanto, apresenta as TDICs e os Gêneros Textuais Digitais, conforme o que propõem: (COSCARELLI, 2016; VALENTE, 2014; MORAN, 2007; SILVA, 2014; ALMEIDA e VALENTE, 2012; ROJO, 2013; SIEMENS, 2006); dentre outros.  Para embasar essa proposta de investigação, fez-se o aporte bibliográfico e teórico. Coletou os dados, aplicando os questionários aos alunos e professores. Tabulou-se os dados para uma análise numérica e descritiva para explorar ou conhecer o tema proposto, baseado no aporte bibliográfico. Assim, o desenho dessa pesquisa, resume-se quanto ao tipo em não experimental, transversal e exploratório. Constatou-se que os respondentes professores e os alunos são, nas palavras de (PRENSKY, 2012), respectivamente, imigrantes e nativos digitais e, que todos os respondentes utilizam dispositivos eletrônicos que permitem as Tecnologias Digitais de Informação e Comunicação. E, quanto aos Gêneros Textuais Digitais os respondentes, na maioria conhecem e até os usam, ainda que não soubessem a sua classificação.
Impacto da dotação orçamentária na eficiência técnica das universidades federais brasileiras
Authors: Da Silva Jheferson Guimarães , De Araújo Kleber Domingos , Suzart Janilson Antonio da Silva , Sousa Marcos de Moraes
Published: January 2023

Essa pesquisa buscou medir a eficiência técnica das 63 universidades federais brasileiras, no período de 2014 a 2019, e identificar o impacto da dotação orçamentária na eficiência, além de outros fatores exógenos que não estão sob controle da instituição, mas podem impactar sua eficiência técnica. O método utilizado, em primeiro estágio, foi a Data Envelopment Analysis (DEA), na sua versão CCR orientada por input, e, em um segundo estágio, foi utilizado uma regressão de método de equação generalizada (GEE) em painel. Os achados apontam que 33% das universidades foram eficientes em todo o período investigado e que apenas uma universidade (UFJF) se apresentou ineficiente em todos os períodos. Em segundo estágio, verificou-se que a dotação orçamentária não influenciou na eficiência técnica das universidades federais, e que as variáveis IDEB e Número de campus influenciaram na chance de eficiência técnica das universidades federais brasileiras. A pesquisa contribui à acerca da eficiência técnica das universidades federais brasileiras e especificidades, às quais não constituem controle total da universidade, especificamente, no que tange ao seu financiamento.
Pattern of Neurological Manifestations in Patients Referred to the Neurology Clinic of a Reference Military Hospital
Authors: Allahyari Fakhri , Abedi Fatemeh , Saberi Isfeedvajani Mohsen , Hosseininejad Anbaran Seyed Javad , Davoudi-Monfared Esmat
Published: January 2023

Background: The field of neurology encompasses a wide range of disease types, and recognizing the most common manifestations of these diseases, particularly in subgroups, is critical for improving appropriate diagnostic and therapeutic measures. Objectives: The purpose of this study was to determine the frequency of common manifestations of neurological diseases in patients referred to a military hospital’s internal neurology clinic. Methods: This was a cross-sectional descriptive study of patients referred to the internal neurology clinic of a reference military hospital, Tehran, Iran in 2020. The sampling was done at random using a checklist. Finally data was analyzed by using SPSS software. Results: Women made up the majority of patients in 336 samples 182 (54.2 %) versus 154 (45.8 %). The patients’ average age was 49.5±16.5 years, with 28.3 % (n=95) being elderly. The three most common complaints raised by patients were headache, movement disorder, and sensory disorder, accounting for 29.5%, 27.7%, and 27.7% of complaints, respectively. Seventeen patients (5.1%) also mentioned other issues, with anger, anxiety, depression, and nausea being the most common complaints. Conclusion: Headache, movement disorder, and sensory disorder are the most common neurological disorders referred to a military hospital. Because of the high prevalence of these issues, it is necessary to establish specialized clinics and conduct additional research to determine the most common types of sensory and movement disorders, as well as the most effective methods of prevention and treatment in medical centers.
The Effects of Nasal Septoplasty on the Severity of Obstructive Sleep Apnea Syndrome: A Quasi-experimental Study
Authors: Avatef Fazeli Manouchehr , Hedayati Arefeh , Dehghani Amrollah , Hedayati Mohamadreza , Zaremehrjardi Fatemeh
Published: January 2023

Background: Sleep disorders of breathing encompass a spectrum of disorders ranging from primary snoring to obstructive sleep apnea syndrome (OSAS), which leads to septoplasty in the most patients. Objectives: The aim of this study was to evaluate the effects of nasal septoplasty surgery on the severity of OSAS. Methods: The current quasi-experimental self-controlled study was conducted on adult patients with deviated nasal septum and were candidate for nasal septoplasty. Before surgery and two months after surgery, patients underwent respiratory polygraph. The parameters assessed included the airflow and oximetry indices. The severity of sleep apnea will be assessed based on the Apnea-Hypopnea Index (AHI). Also, the severity of snoring was scored from zero to 10 based on the visual analog scale (VAS). The severity of daytime sleepiness was also determined using the Epworth Sleepiness Scale (ESS). Data were analyzed by using SPSS software. Results: There was a significant reduction in the mean score of ESS after the surgery (P<0.001), daytime fatigue (P=0.002), and daytime sleepiness (P<0.001). Also, breathing quality during sleep showed that the severity of apnea (P<0.001), snoring (P<0.001), as well as ESS (P<0001) were significantly improved. There were no significant changes in the means of oxygen saturation (P=0.14) and rapid eye movement (REM) sleep (P=0.06) after non-REM stage 1-2 (P=0.09), but following non-REM stage 3-4 significantly improved (P=0.03). Conclusion: The correction of nasal obstruction improved the general health of OSAS patients. These results further reflected that the corrective surgery could improve the patients’ emotional state and social performance, effectively upgrading their quality of life.
Prevalence of Different Types of Craniosynostosis in Isfahan, Iran
Authors: Riazi Ali , Allami Mostafa , Arabi Alireza , Larry Mehrdad
Published: January 2023

Background: Craniosynostosis is a congenital deformity of the skull that occurs at birth. Objectives: This study aimed to investigate the frequency of different types of craniosynostosis in Isfahan, Iran. Methods: In this retrospective study, the records of all patients referred to the pediatric neurosurgery clinic of Imam Hossein children’s hospital in Isfahan, Iran from 2013 to 2018 were diagnosed with craniosynostosis. Incomplete files were excluded. Demographic information of patients and type of delivery, underlying diseases of their parents, diseases of maternal pregnancy, type of craniosynostosis, syndromic or non-syndromic craniosynostosis were collected. Data were analyzed using SPSS software version 22. Results: The diagnosis of craniosynostosis in 63% of cases (n=121) was a single suture and in 37% of cases (n=72) was a complex suture. There was no significant difference in the frequency distribution of craniosynostosis in males and females (P>0.05). Conclusion: Due to the prevalence of 16 cases per 100,000, we can reduce the complications of this disease by educating doctors and parents.
An Investigation of the COVID-19-Related Anxiety Levels of Individuals According to Some Demographic Variables
Authors: Cerit Kamuran
Published: January 2023

Background: Pandemics such as COVID-19 create heightened fear and anxiety, causing deterioration in the behaviours, social and psychological well-being of people. It can be thought that the anxiety levels of healthcare workers will increase more because they have a higher risk of contamination, work under COVID-19 isolation-measures and heavy workload. Objectives: The aim of this study is to determine the COVID-19-related anxiety levels of individuals, the ways of coping with, the demographic factors affecting anxiety, and whether the anxiety level of healthcare workers is different from others. Methods: This study was carried out with data obtained from 1017 participants via google forms between May-July 2020. In the collection of data, the 12-item COVID-19-related anxiety scale, which was developed by researcher and analysed for validity and reliability; 13 items for ways of coping; some demographic questions were used. The COVID-19-related anxiety scale consisted of three dimensions: "cognitive", "physiological and emotional", "behavioural", which explained 71% of the variance. The Cronbach alpha of scale was 0.85. Results: The COVID-19-related anxiety levels of participants were slightly above the moderate level (2.83±0.72). The anxiety levels of healthcare workers were not different from others. There was a difference in anxiety levels according to demographic characteristics of participants, such as age, gender, living in Turkey or abroad, working status/type, and smoking addiction. Cognitive coping, social support, distraction, relaxation techniques were identified as ways of coping with anxiety. Conclusion: COVID-19 pandemic created anxiety in people. More studies need to understand the long-term effects of the pandemic.
A comprehensive review on the phytochemistry, pharmacological, ethnobotany, and traditional uses of Paeonia species
Authors: Kumar Sunil , Ratha Kshirod Kumar , Rao Meda Mruthyumjaya , Acharya Rabinarayan
Published: January 2023

Since ancient times, people have used medicinal plants as a source of medications to treat and prevent diseases. Paeonia species are important therapeutic plants in Ayurvedic, Unani, and Traditional Chinese Medicine. This study aims to provide updated information on the ethnobotany, phytochemistry, and pharmacological activities of Paeonia species discovered until now. Using the keywords "Paeonia", "geographical distribution", "ethnopharmacology and traditional values", "phytochemistry", "antioxidant", "anti-inflammatory", "antimicrobial", "cardiovascular diseases", and "anticancerous properties", the published reports from 2001 to 2022 were retrieved using Google Scholar, Science Direct, PubMed, and Scopus databases. A total of 156 published articles were studied after meeting the qualifying criteria. Out of these, 52 articles were studied for phytochemistry, ethnopharmacological and traditional uses. Paeonia emodi is used to treat hypertension, asthma, convulsions, epilepsy, bronchitis, ascites, uterine abnormalities, and a variety of skin ailments. Bioactive compounds like triterpenes, monoterpene glucosides, phenols, tannins, emodinol, benzoic acid, paeonin A and B, steroids, several secondary metabolites like paeoniflorin and paeonol, and several minerals are abundant in the Paeonia species. In recent studies, Paeonia emodi has been shown to possess pharmacological properties like antioxidant, antibacterial, anti-inflammatory, insecticidal, and anti-tumor activities. Convincing data supports the traditional ethnomedicinal claims of the plant; the abundant phytocompounds of the plant are attributed to its broad spectrum of pharmacological activities. In order to understand the molecular mechanisms underlying the action of the bioactive ingredients in drug development processes and to investigate their potential at the clinical level, more research is required.
Ethnobotany, phytochemistry and pharmacological activities of Celtis australis: A review
Authors: Benamar Khadija , Ibnsouda Koraichi Saad , Fikri-Benbrahim Kawtar
Published: January 2023

Celtis australis is a deciduous plant used worldwide in folk medicine to treat various ailments, such as stomach disorders, cough, pimples, joint pain, amenorrhoea, rheumatism, menstrual disorders, and herpes. The present review aims to document and summarize different works regarding the ethnomedicinal uses, phytochemistry, and biological activities of different parts (fruits, barks, leaves, and seeds) of this medicinal plant. For data collection, Google scholar, Science direct, Scopus, PubChem, and PubMed databases were used. This study shows that C. australis contains several bioactive compounds, exhibiting various pharmacological activities mainly hepatoprotective, analgesic, anti-inflammatory, cytotoxic, antioxidant, and antimicrobial properties. Thus, C. australis is a promising plant that can be exploited in the treatment of various diseases.
Influence of anti-hyperlipidemic activity by co-administration of polyamines and rutin with simvastatin
Authors: Patil Rajesh R , Aswar Manoj K , Bhise Satish B , Naik Suresh R
Published: January 2023

Introduction: Natural polyphenols, rutin, endogenous polycations, and polyamines (spermine and spermidine) are reported to have beneficial effects on hyperlipidemia, obesity, and cardiovascular disease (CVD). The present study attempts to evaluate the combined effects of polyamines or rutin and simvastatin on hyperlipidemic rats. Methods: Wistar rats were maintained on a high-fat diet (HFD) for 60 days. The HFD rats were administered from the 31st day onward with polyamines (PAs), rutin, and simvastatin for the next 30 days. The body weight, serum lipid profile, biomarkers, liver cholesterol, triglycerides, hydroxymethylglutaryl-CoA (HMG-CoA) reductase activity, antioxidants, and marker enzymes in HFD rats were estimated along with the liver histoarchitecture of the rats. Results: The experimental findings demonstrated abnormal alterations in body weight, serum lipid profile, hepatic lipid, and HMG-CoA reductase activity, hepatic antioxidants, serum marker enzymes, blood glucose, total protein, and histoarchitecture of the liver in HFD rats. The aforementioned treatment elicited a significant reduction in the biochemical parameters, biomarkers, and the evaluated enzymes in the present study. Furthermore, an improvement in the histoarchitecture of the liver was observed. Conclusion: The experimental results point out the positive role of antioxidant polyamines along with rutin on different parameters in HFD rats. Thus the combinatorial effect of polyamines and rutin with simvastatin (5 mg/kg) was found to be greater than simvastatin (10 mg/kg) alone. The enhancement in the anti-hyperlipidemic effect of simvastatin may be due to the intrinsic antioxidant property of polyamines and rutin.
Comparative sensitivity of immunodiagnostic tests in vivo (Mantoux and RTA) and in vitro (QuantiFERON – GIT) in children with chronic nonspecific bronchopulmonary pathology associated with various tuberculosis
Authors: Nakonechnaya S. L. , Aksenova V. A. , Mizernitskiy Yu. L.
Published: January 2023

Aim. Selection and combination of immunodiagnostic tests to detect active tuberculosis (TB) in children with concomitant bronchopulmonary pathologies.

Materials and methods. A prospective study of children and adolescents (n = 236) was conducted, which included cases with localized pulmonary tuberculosis; pulmonary tuberculosis associated with allergic or infectious and inflammatory forms of chronic nonspecific lung diseases (CNSLD); chronic nonspecific lung diseases under a significant absence of active TB but the presence of Mycobacterium tuberculosis. All patients underwent immunodiagnostic tests by Mantoux test, recombinant tuberculosis allergen (RTA) test, and QuantiFERON – GIT.

Results. Mantoux and RTA tests were found to exhibit high sensitivity in children both with tuberculosis associated with concomitant pathologies and without such pathologies. Differences were observed in the results obtained by the Mantoux test in children with tuberculosis-associated bronchopulmonary pathology and those with localized tuberculosis. The Mantoux test may be positive as a result of many factors, other than active TB infection. Thus, children with allergic and infectious-inflammatory pathologies of the lungs exhibit an altered sensitivity to the Mantoux test. Such cases require in vitro diagnostics with the Quanti- FERON test, whose sensitivity is high despite the presence of CNSLD.

Conclusions. Children with infectious-inflammatory CNSLD should undergo TB examination in stages based on in vivo and in vitro tests, when necessary. Children with allergic CNSLD should undergo in vitro tests at the first stage.
Tuberculosis prevalence in children in the Northwestern Federal District of Russia before and after COVID-19 pandemic: prognosis and epidemiological models
Authors: Dovgalyuk I. F. , Kudlay D. A. , Starshinova A. A.
Published: January 2023

Aim. To assess changes in the epidemic indicators of tuberculosis infection (TB) in children in the Northwestern Federal District of Russia before and after the COVID-19 pandemic based on mathematical modeling and forecasting.

Materials and methods. The main epidemiological indicators of TB were analyzed using the official statistical data for 2009–2021. A mathematical forecasting of epidemiological indicators was performed based on chest X-ray screening for TB. A statistical analysis was carried out using the software environment R (v.3.5.1) and the commercial software Statistical Package for Social Sciences (SPSS Statistics for Windows, version 24.0, IBM Corp., 2016). Time series forecasting was performed using the programming language of statistical calculations R, version 4.1.2 and the bsts package, version 0.9.8.

Results. The mean regression coefficient of a single predictor was found to differ in a model for TB morbidity in children is 0.0098. X-ray screening for TB was established to be a significant mortality predictor in children. At least 60% of the population should undergo TB screening in order for TB prevalence to be controlled in a country with a population above 140 million people.

Conclusions. The conducted study revealed a positive correlation between the incidence of tuberculosis in children in Russia and TB screening in at least 60% of the population. Under the current TB screening system in Russia, the epidemic TB situation will continue to improve, despite COVID-19 restrictions.  At the same time, in the Northwestern Federal District of Russia, preventive TB screening can be considered sufficient only in the Kaliningrad, Murmansk, and Pskov Oblasts.
Thyroid cancer in the Far Eastern Federal District of Russia
Authors: Gordienko V. P. , Poberezhestsky A. V.
Published: January 2023

Aim. To estimate the geographical specifics of thyroid cancer (TC) morbidity and mortality among residents of the Far Eastern Federal District of Russia (FEFD) in 2008–2020.

Materials and methods. Data on TC morbidity and mortality provided by official statistical records, regulatory documents, as well as observations of TC dynamics were used.

Results. In 2020, 548 new cases of malignant neoplasms of the thyroid gland were registered in the FEFD, which was 84% higher than in 2008 (298 people). The majority of the patients belonged to the age group of 40–60 years old. The number of patients with stages I–II increased (84.1%) under a simultaneous decrease in the number of patients with neglected forms of the disease (15.5%). The share of TC detected during preventive examination comprised 35.9% as compared to 16.0% in 2008. One-year mortality decreased to 3.3% as compared to 7.3% in 2008. At the same time, mortality rates remained at relatively high levels in the context of current achievements in oncology treatment. Morphological confirmation of the diagnosis was carried out in 98.7% of cases, which exceeded slightly the state level of 98.5%. The share of patients diagnosed five or more years ago comprised 66.8%, thus being lower that the national average value of 69.4%. The quality of oncology services was assessed using the index of registration reliability, which did not exceed 0.11 in any of the FEFD regions in the reporting year.

Conclusions. The observed increase in the number of patients with malignant neoplasms in the FEFD in 2008–2020 was accompanied by an increase in the annual incidence of thyroid cancer among both male and female populations, with the mortality levels demonstrating differences in the dynamics (increase/decline in men: – 50%; in women: + 29%).
Echoes of Marginalized Voices in Ranendera’s Lords of The Global Village
Authors: Singh Jaspreet
Published: January 2023

The present study explores the selected text Lords of the Global Village from the perspective of subaltern studies. The text from the perspective of subaltern literary theory focuses on the ‘Asur’ Tribe’s lifestyle, their marginalization by the mainstream, their issues and their conflicts with the dominant structures. The paper, from the vantage point of subaltern studies, aims to explore the underpinnings of this novel. By taking into account the concepts of Subalternity, Hegemony, Resistance, Assimilation, Subversion of establishment, through a subaltern reading of Lords of the Global Village would be analysed. The study explores, treatment given to characters of different groups and ideological implication of this treatment. Gramsci’s concept of hegemony and Ranjit Guha’s ideas of Subalternity have been used for analysing and interpreting the selected work.
Synthesis of amphiphilic molecular brushes by solution radical copolymerization of oligoethylene glycol and oligopropylene glycol methacrylates
Authors: Orekhov D. V. , Ermolaev I. D. , Simagin A. S. , Kamorin D. M. , Savinova M. V. , Arifullin I. R. , Kazantsev O. A.
Published: January 2023

The regularities of radical copolymerization of methoxyoligo(ethylene glycol)methacrylate (MOEGM) with an ethoxylation degree of 11 and methoxyoligo(propylene glycol)methacrylate (MOPGM) with a propoxylation degree of 6 or 10 in toluene solutions were determined. The copolymers formed at low degrees of conversion are enriched with ethoxylated ether units in both pairs of monomers. The relative activities of the comonomers determined by the Fineman-Ross methods are in the range of 1.36–1.88 (MOEGM) and 0.56–0.92 (MOPGM). It has been established that the activity of MOPGM decreases with an increase in the length of the oligopropylene glycol chain.
Technological design of carbon fiber parts with a complex geometric shape for unmanned aerial vehicles
Authors: Sokolov V. V. , Agashina Z. V. , Voinov S. I. , Antipov P. Y. , Golishev O. A. , Dolinsky S. V.
Published: January 2023

In this paper, the process of technological design of small-sized carbon fiber parts with complex geometry used in the design of unmanned aerial vehicles is considered. Approaches to the placement of splicing points in preform layers are presented. Regularities have been established that relate the number and location of splicing points in the reinforcing layers of carbon fiber reinforced composite and its mechanical characteristics.
Influence of cutting ceramics on the formation of the thermoplastics supramolecular structure
Authors: Erenkov O. Yu.
Published: January 2023

The question of the efficiency of turning processing of thermoplastic polymer materials with cutting ceramics is considered. The fact of a decrease in the values of the cutting force when turning the investigated thermoplastics with a tool made of ceramic material KNT16 was experimentally established. It has been experimentally proven that turning caprolon and fluoroplastic using a KNT16 cermet cutting insert leads to the formation of a supramolecular structure of a high degree of homogeneity.
A INFLUÊNCIA DO PLANEJAMENTO A EXECUÇÃO DE OBRAS
Authors: GOMES DA SILVA BRUNO
Published: January 2023

Abstract: In civil construction there is a need to work with several interconnected areas for the success of the building. If there is no good planning can occur numerous setbacks and causing controversies such as: the high cost of building; unnecessary expenditure; non-compliance with deadlines; lack of feasibility of budget and laws; accidents; among other adversities that may arise. The objective of this work is to provide information to civil engineering professionals about the importance of the act of planning, when they require the necessary actions to carry out a satisfactory project, and when it aims at a project without negative impacts, thus generating interfaces for a possible intervention to minimize the occurrence of nonconformities, during the execution of the work. The methodology used is of a qualitative nature with the analysis of the project from the initial design to the final phase of the construction. The results obtained with the answers of solutions and questions for the professionals involved in the project are described in the course of this work.
Las metodologías activas como recurso de enseñanza en las materias de especialidad de informática
Authors: Moreira-Ponce Katiuska Rosalía , Pazmiño-Campuzano Marcos Fernando
Published: January 2023

El objetivo general de la investigación fue determinar la incidencia de las metodologías activas como recurso de enseñanza en las materias de especialidad de informática. El desarrollo de la investigación, se realizó desde la perspectiva cuantitativa, de tipo descriptiva y se complementó por un diseño documental-bibliográfico, permitiendo la recogida de información extraída de los diferentes artículos arbitrados, trabajo de grado entre otros. La investigación descriptiva, es el procedimiento usado en ciencia para describir las características del fenómeno de estudio. Además, se aplicó un cuestionario a un grupo de 143 estudiantes de primero, segundo y tercero de Bachillerato Técnico en Informática, de la Unidad Educativa. Educativa Fiscal Manta. Se concluye que, las metodologías activas aplicadas como herramientas y recursos de enseñanza en las materias de la especialidad informática representan una alternativa fundamental para adquirir conocimientos de manera significativa, incentivando a la creación, autonomía y el interés de los estudiantes por aprender.
The Role of Community Institutions in the Socio-economic Empowerment of Emirati Women Field Study in Ajman
Authors: Yossef Enaam , Nasef Saeed , Yousif Nagwa
Published: January 2023

This study aims to identify the role performed by the UAE society through some of its community institutions (government, private and some civil society organizations and Umm Al-Mu'minin Association as a model) in the empowerment of Emirati women at two social and economic levels, in addition of exploring the mechanisms and programs set by these institutions, to support and integrate women in the society, by emphasizing the importance of their participation as effective actors in the society and towards achieving the sustainable development and as means of their development and prosperity. In-depth interview tool through a case study of a sample of 30 Emirati female citizens. In order to answer the study questions, the researchers used the statistical packages of social analysis (SPSS) using descriptive statistical analysis methods (mean weight arithmetic, standard deviation, and analysis of variances (ANOVA). The correlation coefficient used Pearson's linear correlation coefficient and Spearman rank correlation coefficient and the dimensions of economic and social empowerment. The major findings achieved by the study: 1-There were correlations coefficient attributed to the variables of the family members, place of residence, reason for joining the job and the economic empowerment area. 2-There were correlations coefficient attributed to the variables of the number of family members, the place of residence and the academic qualifications, and the reason for joining the job and the area of social empowerment.
Real-time FPGA implementation of the Semi-Global Matching stereo vision algorithm for a 4K/UHD video stream
Authors: Grabowski Mariusz , Kryjak Tomasz
Published: January 2023

In this paper, we propose a real-time FPGA implementation of the Semi-Global Matching (SGM) stereo vision algorithm. The designed module supports a 4K/Ultra HD (3840 x 2160 pixels @ 30 frames per second) video stream in a 4 pixel per clock (ppc) format and a 64-pixel disparity range. The baseline SGM implementation had to be modified to process pixels in the 4ppc format and meet the timing constrains, however, our version provides results comparable to the original design. The solution has been positively evaluated on the Xilinx VC707 development board with a Virtex-7 FPGA device.
Transparent Dimension Reduction by Feature Construction with Genetic Algorithm
Authors: Radeev Nikita
Published: January 2023

There are domain areas where all transformations of data must be transparent and interpretable (medicine and finance for example). Dimension reduction is an important part of a preprocessing pipeline but algorithms for it are not transparent at the current time. In this work, we provide a genetic algorithm for transparent dimension reduction of numerical data. The algorithm constructs features in a form of expression trees based on a subset of numerical features from the source data and common arithmetical operations. It is designed to maximize quality in binary classification tasks and generate features explainable by a human which achieves by using human-interpretable operations in a feature construction. Also, data transformed by the algorithm can be used in a visual analysis because the algorithm builds features that make space linearly separable using distance criteria in a fitness function to shift classes from each other as far as possible without loss of classification quality. The multicriterial dynamic fitness function is provided to build features with high diversity.
A Reconfigurable Full-Digital Architecture for Angle of Arrival Estimation
Authors: Florio Antonello , Avitabile Gianfranco , Talarico Claudio , Latorraca Pasquale , Coviello Giuseppe
Published: January 2023

In recent years, Real-Time Localization Systems (RTLS) are gaining significant attention from the scientific community. Usually, RLTS rely on positioning techniques based on the electromagnetic (e.m.) propagation properties of the received signals. Among the many possible approaches, RTLS based on the Angle-of-Arrival (AoA) estimation allows for accurate results with a comparatively lower number of receivers. In this work, we propose a novel, fully digital synchronous architecture for AoA estimation based on phase interfer­ometry. After reviewing the state­ of-the-art on full-hardware techniques for localization, the main blocks composing the proposed architecture, are discussed in detail, along with their dimensioning equations. The granularity with which the system estimates the phase shifts used to compute the AoA is reconfigurable according to the desired accuracy. The architecture is lightweight and computes the AoA in real-time. To validate the proposed approach, the RTLS architecture has been implemented on an Intel Cyclone IV E EP4CE115F29C7 FPGA board interfaced with a custom-designed receiver front-end, and experimental results on benchmark applications have been collected and analyzed.
Zira Voice Assistant- A Personalized Interactive Desktop Application
Authors: Titarmare Vedant , CHANDANKHEDE PANKAJ , Wanjari Minakshi
Published: January 2023

Since we know that python is a developing language so it is easy to write a voice assistant script in python. Day by day life became smarter and more connected to technology. We already know some voice services like google, Siri etc. Now in our Zira voice assistance system, it can act as a daily schedule reminder, send emails, calculator, play music and a search tool. Our project works on voice input and provides voice output and displays text on the screen. Our main voice help agenda makes people smarter and delivers faster results with a computer. Voice Help captures voice input with our microphone and transforms our voice into understandable computer language providing the necessary solutions and answers that the user asks. By doing this project, I realized that the concept of AI in all fields reduced human effort and time saving. 