bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of groundwater quality and water table mapping of Bhaktapur Municipality
Authors: Ganesh Razim , Koju Rebika , Prajapati Raja Ram
Published: January 2019

Water is necessary for all life on earth. Every living creature on the Earth depends on water for their survival; however the supply of water on Earth is limited. Groundwater, the important source of water supply to many people around the world, is accessed through stone spouts, springs, dug wells and infiltration galleries in and around Kathmandu Valley since ancient time. The extraction of groundwater in Kathmandu Valley is increasing day by day due to increase in population, haphazard urbanization and unplanned industrialization. Drinking water quality and quantity is one of the major issues which need to be taken seriously, since clean water and sanitation are human rights and essential to life. The present study aims to prepare water table map and groundwater quality map from unconfined aquifer of Bhaktapur Municipality. Geographic Information System (GIS) based groundwater table mapping for 472 samples were used. Inverse Distance Weighted (IDW) method was used for 86 samples for spatial interpolation of chemical indices. Surface maps are prepared for water quality parameters (pH, turbidity, conductivity, TDS, total hardness, iron, ammonia, nitrate, chloride, alkalinity and E-coli) in the GIS Software by interpolation between the available data. Water table elevation map shows that groundwater levels are shallow at wells located close to agricultural field. From the water quality mapping of the Bhaktapur Municipality, it is seen that the most of the water quality parameters are within the maximum permissible limit set by WHO and NDWQS. It is noted that quality of ground water in the study area exceeds Nepal drinking water quality standards on the basis of measured values of chloride, ammonia and nitrate in majority of wells. High concentration of chloride, ammonia and nitrate were found in most of water samples from the central part and in around the periphery of the municipality boundary, which may be due to infiltration of agricultural runoff and leaching of sewage pollutants.
Core and More: Examining Foundational and Specialized Content in Library and Information Science
Authors: Saunders Laura
Published: January 2019

A master’s degree from an ALA-accredited institution can prepare graduates for a wide range of job functions and career paths, but the variety of jobs raises some questions about how LIS programs are meeting the wide range and evolving needs of employers in order to best prepare students for professional positions. What knowledge, skills, and aptitudes (KSAs) are necessary for practitioners? What are common competencies and foundational areas of knowledge that apply across information settings and job functions, and which skills and competencies are specialized enough to be relevant only to certain positions? This study reports on the results of a nationwide survey of over 2,000 practicing information professionals and LIS faculty who were asked to rate 53 skills and competencies as core or specialized. The findings identified 11 core KSAs but also suggest that areas of emphasis vary by type of information setting. The findings have implications for LIS programs and faculty.
Morphological analysis of interstitial Cajal cells and mast cells in experimental hyperactivity bladder and stress incontinence under influence of pharmacocorrection
Authors: Iatsyna O.I. , Vernygorodskyi S.V. , Kostyev F.I.
Published: January 2019

The existing data indicate the multifactorial mechanisms of development of the overactive bladder (OAB) symptom, but the issue of OAB pathogenesis remains unclear. In more recent times, the neurogenic theory of OAB genesis has being accompanied by the increasing attention to the study of morphological changes that occur in the smooth myocytes of the detrusor and their interaction with the extracellular matrix. Therefore, the objective of our study became the evaluation of distribution of interstitial Cajal cells (ICC) and basophilic granulocytes (BG) in the structural elements of the bladder wall under stress urinary incontinence and its overactivity before and after treatment with Mirabegron, Spasmex, Quercetin and combination thereof with testosterone and estradiol, using histochemical and immunohistochemical methods. The experimental models of OAB and stress urinary incontinence (SUI) presented the increase in the amount and functional activity of BG revealed by histological and immunohistochemical methods, as well as ICC at all terms of OAB monitoring, while the SUI presented with high concentration and functional activity of BG only after 14 days of the experiment. After 28 days, we observed a sharp decrease of the parameters, indicating decompensation and depletion of the functional activity. The number of ICC decreased under SUI after both 14 days and 28 days of the experiment. The group of experimental animals receiving Spasmex and its combination with hormones, presented no significant effect on the quantitative and qualitative composition of BG and ICC at OAB and SUI on Day 14 of the experiment, but the combination with testosterone demonstrated statistically reliable (p<0.001) reduction of BG and ICC expression in the muscle layer of the bladder after 14 days, and unreliable after 28 days of the experiment (p>0.05). The administration of Mirabegron alone and especially its combination with testosterone and estradiol presented positive trends in histochemical and immunohistochemical expression of BG and ICC. The experiment proved high efficacy of Quercetin in combination with testosterone and estradiol under OAB and SUI, confirmed by stabilization of the functional activity of BG and ICC quantitative composition.
An inception cohort study of patients in a military clinic treated for lower back pain with lumbar fusion and SIGNAFUSE® with a systematic review of the literature
Authors: Steen Grant
Published: January 2019

Background: Use of synthetic bone graft substitutes for spinal fusion has increased sharply over the past 20 years. SIGNAFUSE® is one such synthetic graft material that provides an osteostimulatory effect for spinal fusion. Because clinical trials are not required for commercialization of synthetic bone graft substitutes in the United States, fusion rates attained using SIGNAFUSE for lumbar fusion are not well documented. The goal of the current study is to determine the rate of spinal fusion in a military clinic following lumbar fusion surgery augmented with SIGNAFUSE.
Methods: We report a retrospective chart review of 8 patients who received lumbar spinal fusion surgery augmented with SIGNAFUSE. All patients were assessed by computed tomographic (CT) imaging at least 1-year post-surgery to determine whether bony fusion had occurred. We also systematically reviewed literature sources that report fusion rate following spinal fusion surgery, for broader context.
Results: An average of 1.6 spinal levels were treated with SIGNAFUSE-loaded interbody cages. All patients had stabilization hardware via pedicle screws or integrated cage fixation. Seven of 8 patients successfully fused, for an overall fusion rate of 87.5% (95% confidence interval: 47.4% to 99.7%). Systematic review of 26 recent publications that included 1,126 patients treated with synthetic bone graft showed that the overall fusion rate in the literature is 84.4%.
Conclusions: Fusion was achieved in 87.5% of patients treated with SIGNAFUSE. This is comparable to the fusion rate in a systematic review of 1,126 patients treated with synthetic bone graft materials.
Composition chimique et activité antimicrobienne de l’huile essentielle de Deverra reboudii (Coss. & Durieu)
Authors: Brahimi S. , Dahia M. , Azouzi B. , Nasri M. , Laouer H.
Published: January 2019

L’huile essentielle de la partie aérienne du Deverra reboudii Coss. & Durieu, obtenue par l’hydrodistillation avec une teneur moyenne de 0,5 % par rapport à la matière sèche, a été analysée par chromatographie en phase gazeuse couplée au spectromètre de masse (GC-MS) qui montre que cette huile est riche en hydrocarbures monoterpéniques (91,41 %), dont principalement : β-pinène (37,64 %), α-pinène (31,77 %), limonène (7,77 %), p-cymène (6,02 %) et β-myrcène (4,48 %). Les activités antimicrobiennes ont fait l’objet de tests sur cinq microorganismes différents. Elles indiquent que l’huile essentielle de Deverra reboudii était active contre Klebsiella pneumoniae, Escherichia coli, Staphylococcus aureus, Bacillus cereus et Candida albicans. Il s’agit du premier rapport sur l’étude de la composition chimique et de l’activité antimicrobienne de l’huile essentielle de cette espèce.
Insights into the mechanism of natural terpenoids as NF-kB inhibitors: an overview on their anticancer potential
Authors: Jain H , Dhingra N , Narsinghani T , Sharma R
Published: January 2019

The transcription factor, nuclear factor kappa B (NF-kB) is one of the principal inducible protein in mammals known to control the gene expression in many critical physiological responses such as oxidative stress, inflammation etc. and has been shown to play an important role in the pathogenesis of cancer. Terpenoids are major constituents present in nutritionally used fruits, vegetables and different spices which possess various pharmacological action including anticancer activity. Various terpenoids, viz. monoterpenoids, sesquiterpenoids, diterpenoids, sesterterpenoids, triterpenoids, tetraterpenoids and polyterpenoids inhibit NF-kB signaling pathway through IkB phosphorylation, DNA binding, p65 translocation etc. Keeping in mind these facts, the present review revealed the anti-cancer potential of naturally occurring terpenoids highlighting their mechanism of NF-kB inhibition. This review also focuses on some of the naturally occurring terpenoids belonging to various chemical categories with potential inhibitory effects on NF-kB and their role in the treatment of cancer.
ROLE OF COMPONENTS OF microRNA MACHINERY IN CARCINOGENESIS
Authors: Kian R , Moradi S , Ghorbian S
Published: January 2019

MicroRNAs (miRNAs) are a broad class of non-coding RNAs nearly 21 nucleotides length, which play crucial functions in posttranscriptional gene regulation. These molecules are associated with many developmental and cellular processes in eukaryotic organisms. Current investigation has reported major factors contributing to miRNA biogenesis and has constituted basic principles of miRNA function. More recently, it was confirmed that various miRNAs are clearly implicated in human malignancies, such as lung, breast, ovarian, bladder, colon cancer and other kinds of carcinoma. In addition, dysregulation in the miRNA machinery elements such as Dicer, Drosha, DGCR8, Argonaut, and TRBP could be involved in the progress of many tumor types. The purpose of the current review was to compile growing information besides how miRNA biogenesis and gene silencing are modified to develop cancer.
Radiation Therapy for Renal Cell Carcinoma
Authors: Choi Rachel , Yu James B.
Published: January 2019

Radiation therapy (RT) has traditionally been disregarded in the primary or adjuvant treatment of renal cell carcinoma (RCC), but recent advances have necessitated a re-examination of the role radiation therapy may be able to play. The advent of stereotactic ablative radiotherapy (SABR), which allows for targeting of disease with higher doses in a shorter window of time, may open up new avenues for RT’s role in the treatment of RCC, a cancer with a relatively low alpha/beta ratio. Thus, this review examines both the history and future of RT in the treatment of RCC with an aim to expand the discussion on treatment options for RCC.
Cell-free Circulating Tumor DNA (ctDNA) in Metastatic Renal Cell Carcinoma (mRCC): Current Knowledge and Potential Uses
Authors: Hahn Andrew W. , Nussenzveig Roberto H. , Maughan Benjamin L. , Agarwal Neeraj
Published: January 2019

Historically, tumor biopsies and clinical laboratory testing have been the gold standard for diagnosis and prognosis in metastatic renal cell carcinoma (mRCC). Genomic profiling in mRCC has traditionally been performed on tumor tissue; however, challenges and limitations in obtaining tissue biopsies led to the discovery of alternative biological specimens, namely circulating cell-free DNA (cfDNA). Rapidly evolving technologies, with increased sensitivity and specificity, have been used to query cfDNA in the clinical research setting. These investigations are rapidly establishing cfDNA and liquid biopsies as valuable complementary specimens to the gold standard, and in some instances surpassing these with unique insight into the contemporary genomic landscape and tumor heterogeneity. In this review, we will discuss recent research into the prognostic, diagnostic, and predictive utility of liquid biopsies in mRCC. We will explore their potential role in precision treatment of mRCC and conclude with what is needed in order to translate them to clinical practice.
Razumkov Center. Religion and Church in the Ukrainian society
Authors: Of the Journal Editorial board
Published: January 2019

Results of a study conducted by the Razumkov Center Sociological Service March 25-30, 2016 in all regions of Ukraine (excluding Crimea and the occupied territories of Donetsk and Luhansk Oblasts). 2018 respondents were interviewed at the age of 18 years.
Scientific publications Branch of Religious Studies 2014-2015
Authors: Of the Journal Editorial board 
Published: January 2019

Scientific publications Branch of Religious Studies 2014-2015
Table of Contents
Authors: Of the Journal Editorial board
Published: January 2019

Table of Contents
Prints of Department of Religious Studies on the topic
Authors: Of the Journal Editorial board
Published: January 2019

Prints of Department of Religious Studies on the topic
The authors of labor units
Authors: Of the Journal Editorial board
Published: January 2019

The authors of labor units
The authors of the articles of the magazine "Ukrainian Religious Studies" No. 79
Authors: Of the Journal Editorial board
Published: January 2019

The authors of the articles of the magazine "Ukrainian Religious Studies" No. 79
Title page
Authors: Of the Journal Editorial board
Published: January 2019

Title page
Thank God for the gift of the unity of the Church
Authors: Society of St. Sophia Press service
Published: January 2019

On December 15, 2016, in the Pontifical Lutheran Cathedral of St. John the Baptist in Rome, His Beatitude Sviatoslav, the Head of the UGCC, headed the thanksgiving to the Bishops' Divine Liturgy on the occasion of the 420th anniversary of the Union of Brest. Along with numerous faithful and clergy, the Head of the UGCC thanked God for the "unity of the Church".
Greek Catholic and Roman Catholic Churches in the Department of Religious Studies
Authors: Of the Journal Editorial board
Published: January 2019

Greek Catholic and Roman Catholic Churches in the Department of Religious Studies
The textbooks of the Department of Religious Studies of the National Academy of Sciences of Ukraine in 2017
Authors: Of the Journal Editorial board
Published: January 2019

The textbooks of the Department of Religious Studies of the National Academy of Sciences of Ukraine in 2017
Survey on Factors Determining the Share Price Movement in Indian Stock Market - A Big Data Approach
Authors: K. P. Nitha , Sivakumari S.
Published: January 2019

The aim of investors of any stock is to earn reasonable returns. This paper presents a framework on share price movement and investigates the factors determining and predicting the share prices in Indian stock market through big data approach. This study is also trying to focus on the fundamental factors, technical factors and sentimental factors that stimulate the share price movement. The methodology used mainly focuses on the implications of the theory of financial markets and features affecting the share price movement. Stock market is one of the burning areas where data is growing day by day. Big data Analytics is a very promising area and buzzword for the next generation information technologies. Because of the heterogeneity and other complexities of data, big data architecture and design, is needed which specifically deals with the stock market data and analyze the heterogeneous data for the future prediction of the market. Variety and large Volume of factors exists. Moreover, the velocity with which data generates and the effect of them in the share price movement emphasizes, role of big data in predicting the share prices in Indian Stock Market.
Cyber Security, Challenges, Some Practical Solutions
Authors: Bharadwaj Y. V. Sai , Y. V Sai Bhageerath , Rao Y.V.S.S.S.V. Prasada
Published: January 2019

Cybercrime continues to surge without a slowdown in sight. The cyber security threat continues to worsen. In the first half of 2018, the number of cyber breaches soared over 140% from a year earlier, leading to 33 billion compromised data records worldwide. Cyber Security news such as Marriott hack in Nov 2018 is dominating headlines and becoming a serious headache for business leaders. Malicious outsiders sparked more than half of the 944 breaches and accounted for roughly 80% of stolen, compromised or lost records. Identity theft continues to lead data breach types, but financial access incidents are escalating in severity as well. The United States continues to be the favorite target, and data breaches at major US enterprises continue to grab the headlines. In 2018, the most notable breaches have occurred at Adidas, FedEx, Jason’s Deli, Macy’s, Under Armour, Nordstrom’s and the most popular Facebook. [1].
Analysis of Competitiveness and Threshold Price Transmission of Indonesian Coffee in Importing Countries
Authors: Hadi Sulistyo , Hakim Dedi Budiman , Novianti Tanti
Published: January 2019

Coffee is a leading commodity export in Indonesia and contributes greatly to the national coffee exports. Indonesia is the world's fourth largest exporter. The objectives of this study are investigating business competitiveness of Indonesian coffee compared to the other of coffee exporting countries and threshold price transmission in importing countries uses Constant Market Share Analysis (CMSA) and ECM models , and threshold cointegration . The results concluded that the most influencing business competitiveness was the effect of market distribution, threshold price transmission of Indonesian coffee in importing markets, the United States amounting to 0.9, Germany at -0.6, Japan at 0.5, Italy at 0.2, and Malaysia at -0.4. This means that when the coffee price of deviation in importing countries and Indonesia in its long-term balance exceeds its threshold value, coffee prices in importers countries will adjust to achieve their balance so that both coffee prices are in the Indonesian market and the markets of countries importers have a cointegration relationship.
Cloud Computing : An Overview
Authors: Singh Saumitra
Published: January 2019

Cloud computing is a technology that allows user to use computation, storage and data access services. Cloud computing is about moving services, computation and data for cost and business advantage. It is a location-transparent, centralized facility. These services are provided on the basis of cast. By making data available in the cloud, it can be more easily accessed often at much lower cost, increasing its value by enabling opportunities for enhanced collaboration, integration, and analysis on a shared common platform. This paper explores the definition, nature and potential of cloud computing and research questions related to cloud computing.
TEACHING READING BY UTILIZING HOT POTATOES SOFTWARE TOWARD STUDENTS’ READING COMPREHENSION OF DESCRIPTIVE TEXT
Authors: Farih Abdullah
Published: January 2019

The objective of this study is to measure whether there is or not significant effect of teaching reading by utilizing Hot Potatoes software toward students’ reading comprehension of descriptive text. The variables used were the teaching treatment of Hot Potatoes Software as the independent variable and the students’ reading comprehension of Descriptive Text as dependent variable. Then, the research designed was Quasi-experimental design and the presentation of data used was quantitative. The data were obtained from the eleventh grade, of which 28 students were taken as sample. The students are divided into two groups; experiment group consisted of 12 students and control group consists of 16 students. To get the data, the pre-test and post-test were applied and then analyzed using t-test formula. The researcher had concluded that there is Significant effect of Hot Potatoes Software toward the students’ reading comprehension achievement. The result showed that mean of students’ post-test was increased. It is proved by the t-test (8.54) which is higher than t-table (2.05) at level of significance 5%. It means that the alternative hypothesis was accepted and it proved that Hot Potatoes Software had significant effect toward students’ reading comprehension of Descriptive Text
EDUCATION AS HARMONY INTELLIGENCE AND HEALTH
Authors: Boltivets Sergii
Published: January 2019

The emergence of a public request for the realization of special abilities of a person, focused on children, is typical for countries where awareness of their own intellectual backwardness has become a consequence of comparison with others. This is the so-called post-totalitarian or, more specifically, post-communist countries, different from the free world, as thoroughly proved by the study "Psychotherapy in the Western World and in the USSR" (1973) by one of the most prominent hypnotherapists and psychotherapists of the world Dr. Eugene Hlywa (Sydney, Australia). In particular, a definite stature, inherent in every human population, the aggregate of the capacities of people's abilities is roughly equal in each country. However, the countries of the free world, by their freedom of expression and respect for this individual self-expression, create conditions for the implementation of any capacities of abilities, while totalitarian - only conditions for a relatively small number of able people, sufficient to serve the interests of the ruling elite. Everyone else, as it was already in the history of Ukraine at the beginning of the 20th century, was destroyed: most Ukrainian kobzars were shot at Kharkiv, Ukrainian poets, writers and playwrights - shot in the Sandarmokh Karelian tract, etc. Comparison of ancient Greek cities confirms the vitality of Athens as a city of free prosperity of human abilities and the decline of Sparta, which served as an example of a state organization for future communist and national-socialist leaders of the USSR and the Third Reich.
EVALUATION OF THE NOMOPHOBIA’S PREVALENCE AND ITS IMPACT ON SCHOOL PERFORMANCE AMONG ADOLESCENTS IN MOROCCO
Authors: Louragli Ismail , Ahami Ahmed , Khadmaoui Abderrazak , Mammad Khaoula , Lamrani Anass Chaker
Published: January 2019

Social networks are a new form of addiction to technology and are beginning to take place in the moroccan society in the last decades, especially among children and adolescents. Furthermore the Nomophobia is a new form of addiction to new generations of mobile phones. Because of the importance of their speed spread and their influence on the person's future and interpersonal relationships, we conducted a study to calculate the degree of Nomophobia in adolescent population.
It is through the establishment of a questionnaire for a sample of 541 adolescents including 298 girls and 243 boys of young Moroccans and a test on Nomophobia NMP-Q. The statistical result stated that 69.1% of girls and 63% of boys have Nomophobia in a moderate and severe state, and that the Smartphone is more solicited than the laptop with a negative correlation between school performance and the score of Nomophobia. Thus, poor school performance and mental disorders in adolescents can be explained by taking Nomophobia.
MYTHODRAMA GROUP PSYCHOTHERAPY APPROACH FOR ADOLESCENTS WITH BEHAVIOR DIFFICULTIES
Authors: Tiabashvili Tinatin , Mirtskhulava Rusudan , Japaridze Marine
Published: January 2019

Mythodrama group psychotherapy approach of resolving conflict and bullying has been successful as an intervention in a school setting. This study aimed to provide further evaluation of Mythodrama group approach. A total of 97 Georgian adolescents (Mean of age = 14.65, SD = 1.76) participated in the controlled experimental study. Participants of the experimental group received a Mythodrama group intervention during a period of three months. Analyses revealed a significant increase in emotional intelligence, prosocial behavior and adaptive coping strategies in the intervention group. No significant changes were observed in the control group. The findings suggest that adolescents’ behavior, trait emotional intelligence and coping strategies can be improved using Mythodrama intervention. Follow-up research is required to reveal the persistence and replicability of the result.
Towards Functional Silicon Nitride Coatings for Joint Replacements
Authors: Filho Luimar , Schmidt Susann , Leifer Klaus , Engqvist Håkan , Högberg Hans , Persson Cecilia
Published: January 2019

Silicon nitride (SiNx) coatings are currently under investigation as bearing surfaces for joint implants, due to their low wear rate and the good biocompatibility of both coatings and their potential wear debris. The aim of this study was to move further towards functional SiNx coatings by evaluating coatings deposited onto CoCrMo surfaces with a CrN interlayer, using different bias voltages and substrate rotations. Reactive direct current magnetron sputtering was used to coat CoCrMo discs with a CrN interlayer, followed by a SiNx top layer, which was deposited by reactive high-power impulse magnetron sputtering. The interlayer was deposited using negative bias voltages ranging between 100 and 900 V, and 1-fold or 3-fold substrate rotation. Scanning electron microscopy showed a dependence of coating morphology on substrate rotation. The N/Si ratio ranged from 1.10 to 1.25, as evaluated by X-ray photoelectron spectroscopy. Vertical scanning interferometry revealed that the coated, unpolished samples had a low average surface roughness between 16 and 33 nm. Rockwell indentations showed improved coating adhesion when a low bias voltage of 100 V was used to deposit the CrN interlayer. Wear tests performed in a reciprocating manner against Si3N4 balls showed specific wear rates lower than, or similar to that of CoCrMo. The study suggests that low negative bias voltages may contribute to a better performance of SiNx coatings in terms of adhesion. The low wear rates found in the current study support further development of silicon nitride-based coatings towards clinical application.
A Novel Process for Production of Calophyllum Inophyllum Biodiesel with Electromagnetic Induction
Authors: Kurniati Sri , Soeparman Sudjito , Yuwono Sudarminto Setyo , Hakim Lukman , Syam Sudirman
Published: January 2019

A novel method as proposed in the production of Calophyllum inophyllum biodiesel has been investigated experimentally. This study reports the results of biodiesel processing with electromagnetic induction technology. The applied method is aimed to compare the results of Calophyllum inophyllum biodiesel processing among conventional, microwave and electromagnetic induction. The degumming, transesterification, and esterification process of the 3 methods are measured by stopwatch to obtain time comparison data. Characteristics of viscosity, density, and fatty acid metil ester (FAME) are obtained from testing of a Gas Chromatography-mass Spectrometry (GCMS) at the Integrated Research and Testing Laboratory, Gadjah Mada University, Yogyakarta. The results present that the biodiesel produced by this method satisfies the biodiesel standards and their characteristics are better than the biodiesel produced by conventional and microwave methods. The electromagnetic induction method also offers a fast and easy route to produce biodiesel with the advantage of increasing the reaction rate and improving the separation process compared to other methods. This advanced technology has the potential to significantly increase biodiesel production with considerable potential to reduce production time and costs.
Coaching and Prompting for Remote Physical Activity Promotion: Study Protocol of a Three-Arm Randomized Controlled Trial (Movingcall)
Authors: Fischer Xenia , Donath Lars , Zwygart Kimberly , Gerber Markus , Faude Oliver , Zahner Lukas
Published: January 2019

Background. Physical inactivity is currently seen as one of the biggest global public health issue. Remote physical activity (PA) promotion programs are expected to be effective if they are individually tailored and include behavior change techniques, personal coaching, and regular prompting. However, it is still not fully understood which intervention components are most effective. This paper describes the rationale and design of a study on an individually tailored remote PA promotion program comparing the efficacy of coaching and prompting with a single written advice. Methods. In total, 288 adults (age 20 to 65 years) were randomly assigned to three different intervention arms of a 6-month-long PA promotion program. A minimal intervention group received a single written PA recommendation. The two remaining groups either received telephone coaching sessions (n = 12 calls) with or without additional short message service (SMS) prompting (n = 48 SMSs for each participant). Data assessment took place at baseline, at the end of the intervention, and after a six-month follow-up-period. The primary outcome of the study was self-reported PA. Objectively assessed PA, psychosocial determinants of PA, well-being, body mass index (BMI), and adherence were assessed as secondary outcomes. Conclusion. Findings of this three-arm study will provide insight into the short and long-term effects of coaching and prompting for PA promotion.
The Factors Affecting Older Adults’ Intention toward Ongoing Participation in Virtual Reality Leisure Activities
Authors: Yeh Tsu-Ming , Pai Fan-Yun , Jeng Mei-Yuan
Published: January 2019

Due to the aging of organs, older adults may have limited physical strength for participating in outdoor activities. Therefore, indoor activities offer an alternative for maintaining the health of older adults. Following advances in technology, individuals can use virtual reality to exercise in their homes and are no longer subject to the constraints of the outdoor environment or weather conditions. In addition, these activities are easier to participate in when compared to real-world leisure activities. The present research included 294 older adults as its research subjects. They were given firsthand experience of Wii games for 10 weeks, in order to examine the ongoing participation intention of older adults following an experience with virtual reality leisure activities. The study found that experience attributes, experience consequences, and experience values were important factors in determining ongoing participation intention and can effectively predict ongoing participation intention. Four experience attributes—ease of use, usefulness, safety and flexibility, and fun—significantly influenced the experience value and experience consequences of older adults’ participants. Experience values also influenced ongoing participation intention.
Magnetic Domain Walls and Macroscopic Magnetization-Related Elastic and Anelastic Effects during Premartensitic Transition in Ni2MnGa
Authors: Kustov Sergey , Rosselló Jaume , Corró Miguel Lluís , Kaminskii Vladimir , Sapozhnikov Konstantin , Saren Andrey , Sozinov Aleksei , Ullakko Kari
Published: January 2019

The temperature and field dependences of internal friction and Young’s modulus are studied using a high-resolution ultrasonic (90 kHz) technique in stoichiometric ferromagnetic Ni2MnGa shape memory alloy close to the premartensitic transformation temperature, TPM, in the demagnetized state and under moderate fields. Several new effects observed like an apparent Young´s modulus softening close to TPM under moderate fields, instead of the hardening outside this range, as well as existing controversies in the apparent elastic and anelastic properties of Ni2MnGa close to TPM are explained by microeddy and macroeddy current relaxations that to date have been disregarded.
Wear Behavior of Graphene-Reinforced Alumina–Silicon Carbide Whisker Nanocomposite
Authors: Smirnov Anton , Peretyagin Pavel , Solís Pinargote Nestor Washington , Gershman Iosif , Bartolomé Jose F.
Published: January 2019

In the present work, the tribological properties of graphene-reinforced Al2O3-SiCw ceramic nanocomposites fabricated by spark plasma sintering were studied against alumina ball. Compared with pure ceramic, the wear resistance of these nanocomposites was approximately two times higher regardless of the applied load. It was confirmed by Raman spectroscopy that the main factor for the improvement of the wear resistance of the Al2O3-SiCw/Graphene materials was related to the formation of protecting tribolayer on worn surfaces, which leads to enough lubrication to reduce both the friction coefficient, and wear rate.
Study of the Degradation of Trimethoprim Using Photo-Fenton Oxidation Technology
Authors: Wang Qi , Pang Wenjing , Mao Yingdan , Sun Quan , Zhang Pengfei , Ke Qiang , Yu Hengguo , Dai Chuanjun , Zhao Min
Published: January 2019

Trimethoprim is one of the representative drugs within the pharmaceutical and personal care products (PPCPs) group. The photo-Fenton oxidation technology was used to degrade trimethoprim in wastewater and the extent of degradation was analyzed by using high-performance liquid chromatography, then experimentally obtained the optimal conditions. Analysis of the experimental data showed that, under the single-factor experimental conditions, the optimal conditions for degradation were a pH of 4, an H2O2 concentration of 3.0 mmol/L, an FeSO4 concentration of 0.06 mmol/L, an initial trimethoprim concentration of 0.0689 mmol/L, and an ultraviolet (UV) intensity (UVA) of 12 mW/cm2. The interaction of pH and the concentration of H2O2 and Fe2+ have been further explored, it was obtained the following response surface results through the central composite design experiment: pH = 4.56, H2O2 concentration = 0.09 mmol/L, and Fe2+ concentration = 0.09 mmol/L. Under these conditions, it can be obtained a degradation rate of 99.95% after 6 min. There were similar results for three sets of parallel experiments, indicating that these simulation conditions were feasible.
Relationships between Peritoneal Protein Clearance and Parameters of Fluid Status Agree with Clinical Observations in other Diseases that Venous Congestion Increases Microvascular Protein Escape
Authors: Krediet Raymond T. , Yoowannakul Suree , Harris Lauren S. , Davenport Andrew
Published: January 2019

Background

Peritoneal effluent from peritoneal dialysis (PD) patients contains proteins, mainly transported from the circulation through large pores in the venular part of the peritoneal micro-vessels. Hydrostatic convection is the major driver for peritoneal protein transport, although in PD there is additional diffusion. Consequently, venous pressure may have a role in peritoneal protein transport. The aim of the study was to investigate the importance of venous congestion on the magnitude of peritoneal protein clearance in incident PD patients using non-invasive measurements.

Methods

A total of 316 adult PD patients, on PD for 8 - 12 weeks and collecting 24-hour urine and dialysate for total protein determination, underwent standard peritoneal equilibration testing (PET) along with measurement of N terminal pro-brain natriuretic peptide (NT-proBNP) and C-reactive protein (CRP), multifrequency bioimpedance analysis, and a transthoracic echocardiogram.

Results

Statistically significant univariate relationships for peritoneal protein clearance with a Spearman correlation coefficient > 0.25 were present for 4-hour dialysate/plasma (D/P) creatinine, NT-proBNP, extracellular/total body water, extracellular water excess, left ventricular mass, and right atrial area. Negative correlations were found with serum total protein and residual renal function. On multivariate analysis, logNTproBNP (β 0.11, p = 0.007) and right atrial area (β 0.01, p = 0.03) were significant independent predictors of peritoneal protein clearance.

Conclusion

Indicators of venous congestion showed the most important relationships with peritoneal protein clearance. These indicators have not been assessed in previous studies on the presence or absence of relationships between peritoneal protein clearance and mortality.
Longitudinal Trends in Quality of Life and Physical Function in Frail Older Dialysis Patients: A Comparison of Assisted Peritoneal Dialysis and In-Center Hemodialysis
Authors: Iyasere Osasuyi , Brown Edwina , Gordon Fabiana , Collinson Helen , Fielding Richard , Fluck Richard , Johansson Lina , Morgan Neal , Stoves John , Vardhan Anand , Woodrow Graham , Davenport Andrew
Published: January 2019

Background

In-center hemodialysis (HD) has been the standard treatment for older dialysis patients, but reports suggest an associated decline in physical and cognitive function. Cross-sectional data suggest that assisted peritoneal dialysis (aPD), an alternative treatment, is associated with quality of life (QoL) outcomes that are comparable to in-center HD. We compared longitudinal changes in QoL between modalities.

Methods

We enrolled 106 aPD patients, matched with 100 HD patients from 20 renal centers in England and Northern Ireland. Patients were assessed quarterly for 2 years using the Hospital Anxiety and Depression Scale (HADS), SF-12 physical and mental scores, symptom score, Illness Intrusiveness Rating Scale (IIRS), Barthel's score, and the Renal Treatment Satisfaction Questionnaire (RTSQ). Mixed model analysis was used to assess the impact of dialysis modality on these outcomes during follow-up. P values were adjusted for multiple significance testing.

Results

Multivariate analysis showed no difference in any of the outcome measures between aPD and HD. Longitudinal trends in outcomes were also not significantly different. Higher age at baseline was associated with lower IIRS and RTSQ scores during follow-up. One-hundred and twenty-five (60.6%) patients dropped out of the study: 59 (28.6%) died, 61 (29.6%) withdrew during follow-up, and 5 (2.5%) were transplanted.

Conclusions

Quality of life outcomes in frail older aPD patients were equivalent to those receiving in-center HD. Assisted PD is thus a valid alternative to HD for older people with end-stage kidney disease (ESKD) wishing to dialyze at home.
An Intervention Design: Supporting Skills Development for Peritoneal Dialysis Trainers
Authors: Chow Josephine S.F. , Cho Yeoungjee , Equinox Keri-Lu , Figueiredo Ana , Frasca Serena , Hawley Carmel , Howard Kirsten , Johnson David W. , Jose Matthew , Lee Anna , Maley Moira , Moodie Jo-Anne , Brent Peta-Anne , Pascoe Elaine , Reidinger Donna , Steiner Genevieve Z. , Tomlins Melinda , Voss David , Woodward Paula , Boudville Neil
Published: January 2019

Background

Peritoneal dialysis (PD) is a home-based therapy where nurses train patients in its use. There has been no published randomized controlled trial (RCT) evaluating any specific protocol for nurses delivering PD training. A standardized education package based upon the best available evidence and utilizing modern educational practices may lead to improved patient outcomes. The aim is to develop a standardized, evidence-based curriculum for PD trainers and patients aligned with guidelines from the International Society for Peritoneal Dialysis (ISPD), using best practice pedagogy.

Methods

A literature search and clinical audit were conducted to identify current practice patterns and best practice. Results were reviewed by a focus group of practitioners comprising PD nurses, nephrologists, consumers, a medical education expert, and an eLearning expert. From this, a training curriculum and modules were developed.

Results

A comprehensive PD training curriculum has been developed, which includes modules for training PD nurses (trainers) and patient training manuals. The package comprises 2 introductory modules and 2 clinical case modules. The curriculum is designed for both interactive digital media (trainers) and traditional paper-based teaching with practical demonstrations (patients). Assessment is also addressed.

Conclusion

The need for the development of a comprehensive and standardized curriculum for PD nurse trainers and their patients was confirmed. This paper outlines the process of the development of this curriculum. Pilot testing of the modules was launched in late 2017 to examine feasibility, and planning has commenced for a RCT in 2019 to investigate the effect of the modules on clinical outcomes, and their wider application across Australia and New Zealand.
Dans les bons comme dans les mauvais moments ?
Authors: Barbot Michela
Published: January 2019

Cet article se propose de comprendre si, et comment, les façons de localiser et de décrire les immeubles à Milan entre XVI e  et XVII e  siècle changent à la suite de l’inversion du cycle économique et démographique de la ville. Pendant la période sous observation, Milan passe d’une situation de croissance à une crise généralisée qui se manifeste en correspondance des turbulences financières des années 1619- 1622 et de la peste de 1630. En s’appuyant sur une série de sources différentes – actes de vente et d’achat des immeubles, expertises, plans et dessins des architectes et des ingénieurs, mémoires et suppliques des locataires, documents fiscaux, cadastraux et administratifs des magistratures urbaines –, cette enquête confirme l’existence d’un lien très fort entre les transformations sociales, économiques et matérielles connues par la ville et les changements de repères et de langage enregistrés par les documents.
L’îlot comme unité spatiale de référence
Authors: Marin Brigitte
Published: January 2019

À Madrid, la Visita general de la Regalía de Aposento de 1750-1751, une vaste opération de mesure et de classification de l’espace réalisée pour l’administration fiscale, débouche sur l’affectation d’un numéro à chaque îlot, ainsi qu’à chaque maison en référence à cette unité morphologique de base. Aussi, cette enquête est-elle à l’origine d’un système de localisation et de repérage dans l’espace urbain qui reste en vigueur jusqu’en 1835, lorsqu’un numérotage des maisons par rue remplace celui par îlot. À partir des années 1760, les manzanas (îlots), identifiées par leur numéro, de 1 à 557, sont adoptées comme des unités spatiales de référence pour réaliser des enquêtes et des réformes urbaines, notamment dans les domaines sanitaires et policiers. Mais ce système de repérage ne reste pas confiné aux besoins de l’administration et, progressivement, les habitants ordinaires, dans leurs pratiques quotidiennes, s’approprient ce dispositif.
Se perdre et se retrouver dans le bazar de Mexico
Authors: Exbalin Arnaud
Published: January 2019

A l’instar des cités du Nouveau Monde, la ville de Mexico se caractérise par son réseau de rues en damier. Il était a priori plus facile pour le quidam de s’y repérer que dans les capitales européennes au tracé de rues médiéval. Pourtant, au cœur de la capitale de la Nouvelle-Espagne, sur la Plaza Mayor se trouvait un immense marché, le Baratillo , décrit par les chroniqueurs de l’époque comme un labyrinthe tant les échoppes et les étals s’entremêlaient et formaient un réseau inextricable d’allées. Les chalands ne s’y retrouveraient guère et les auxiliaires de justice et de police étaient déroutés lors des appréhensions. En 1791, le bazar du Baratillo est éradiqué au terme d’un siècle de tentatives de réformes infructueuses. Un nouveau marché aux échoppes numérotées et alignées au cordeau est fondé sur une place adjacente à la Plaza Mayor. Cet article questionne les modalités de ce transfert et les enjeux liés au numérotage des boutiques.
Aménager l’espace et contrôler la population
Authors: Lucrezio Monticelli Chiara
Published: January 2019

La mise en place des bureaux de police sur le territoire de Rome, commencée pendant la Repubblica giacobina et achevée avec l’institution de la première Direction Générale de police pontificale en 1816, implique la réalisation d’un nouveau système administratif dans la ville ainsi qu’une nouvelle conception de l’aménagement de l’espace. La géographie urbaine, modifiée d’abord avec la division en sections et circonscriptions, ensuite avec les giustizie di pace de la période napoléonienne, et enfin à travers l’institution des Presidenze regionarie di polizia pendant la Restauration, joue un rôle important dans la remise en cause de la modalité de repérage dans la ville. Mais c’est surtout le but principal de la police locale, à savoir la capacité à mesurer le territoire et à évaluer la population, que modifient profondément les pratiques administratives d’enregistrement et de localisation, aussi bien que leurs usages sociaux. Le mélange entre les sources abritées par les Archives Nationales de France (sous-séries Pays annexé ou dépendants et Police Générale ) et par l’Archivio di Stato de Rome (fonds Direzione Generale di Polizia e Miscellanea Statistica ), montre bien l’augmentation de la documentation (cartographies de quartiers, listes des habitants, registres de déplacements) liée à ces nouvelles compétences de l’institution policière. En plus, dans un contexte politico-institutionnel très particulier tel que l’État Pontifical, ces attributions administratives finissent par se superposer aux tâches de contrôle traditionnellement prises en charge par les magistratures urbaines ecclésiastiques, en premier lieu le réseau paroissial.
L’organisation d’une poste à domicile à Lisbonne durant la première moitié du xix e siècle
Authors: Vidal Frédéric
Published: January 2019

Cet article s’intéresse aux processus d’identification des domiciles des habitants de Lisbonne à la fin de l’époque moderne. Il a pour objet d’étude de pratiques administratives mises en place au moment de l’organisation d’une poste à domicile, entre la fin du XVIII e  siècle et le début du XIX e . Les étapes de l’organisation de ce service permettent d’observer, à travers la production d’un discours spécifique sur l’espace urbain mais aussi la mise en place de pratiques élémentaires et quotidiennes, le jeu d’influence et de confrontation entre différents modes de perception et d’identification de l’espace urbain. On cherche ici à comprendre en quoi l’usage de ces différents systèmes, qui sont perçus comme étant complémentaires plus qu’en opposition, renvoie à une tentative de prise en compte de la complexité croissante des modes d’habiter en ville à la fin de l’époque moderne.
Crédit et transfert de capitaux à Saragosse au xv e siècle
Authors: Viu Fandos María
Published: January 2019

Parmi les méthodes de règlement et de virement les plus courantes en Aragon à la fin du Moyen Âge, la commande ( commenda ), était une formule très répandue qui permettait de réaliser des prêts et des investissements, apparemment sans intérêts. De plus, le document, simple reconnaissance de dette, a permis de masquer plusieurs transactions financières souvent difficiles à identifier. Dans cet article, nous allons nous concentrer sur les commandes passées devant Antón de Aldovera, notaire de Saragosse, spécialisé dans le secteur commercial. Au cours des années 1415-1440, près de 300 commandes ont été faites devant ce notaire par l’élite commerciale aragonaise, maniant des sommes de 20 à 3.000 florins d’Aragon. Notre objectif est d’analyser ces commandes, leur fonctionnement, leurs caractéristiques, les marchands impliqués, les montants négociés et, surtout, leur finalité.