bluuebunny/crossref_metadata_2025 huggingface dataset:
Le dilemme des déterminants. La réception du naturalisme de Zola par Hermann Broch et George Saiko et leur « naturalisme élargi »
Authors: Müller Sabine
Published: January 2021

Cet article est consacré à deux écrivains autrichiens dont l’intérêt pour le naturalisme se manifeste à un moment où même sa critique par les tenants de la modernité viennoise appartient déjà au passé. Les deux auteurs profitent de ce décalage temporel pour pratiquer, sous le signe d’un « naturalisme élargi » (Broch), une poétique néo-naturaliste originale. L’article vise à reconstruire deux aspects qui ont particulièrement marqué leur stratégie littéraire. D’une part, il montre dans quelle mesure il s’agit là d’un positionnement à l’intérieur du champ littéraire contemporain, dans lequel différentes positions liées à la réception du naturalisme se font concurrence ; d’autre part, prenant en compte particulièrement la réception de Zola par Broch, il défend l’idée que le développement de ce nouveau positionnement exige des auteurs de relever un défi. Car ils sont confrontés à un dilemme constitué, d’un côté, par le maintien du présupposé naturaliste que des conditions extérieures déterminent le sujet, et, de l’autre, par l’attractivité de procédés littéraires bien établis depuis peu, comme la narration scénique, mettant l’accent sur des déterminants intérieurs, psychiques. Ils essaient de s’en sortir par des solutions qui, d’une manière signifiante, divergent aussi bien dans la théorie que dans la pratique.
Finis Austriae. Prager Rückblicke auf die Habsburgermonarchie
Authors: Höhne Steffen
Published: January 2021

Das Jahr 1918 bedeutet für Zentraleuropa einen grundlegenden Einschnitt auf der politischen wie der lebensweltlichen Ebene. Wie reagiert die Literatur auf diesen Einschnitt? Am Beispiel deutschsprachiger Autoren aus Prag, Rilke und Kafka, Brod, Urzidil, Winder und Werfel werden sowohl die Auseinandersetzungen mit dem Jahr 1918 aus jeweils unterschiedlichen Perspektiven und Erfahrungen (nach 1918, nach 1933, nach 1945) als auch die über 1918 hinauswirkenden habsburgischen Prägungen untersucht.
« Die Erstaufführung einer tschechischnationalen Oper ». Jenůfa à Vienne
Authors: Vassogne Gaëlle
Published: January 2021

L’opéra de Leoš Janácek, Jenůfa, représenté pour la première fois à Brno en 1904, dut patienter douze ans avant d’avoir les honneurs du Théâtre national tchèque de Prague : amis et admirateurs du compositeur parvinrent à vaincre la résistance du chef d’orchestre Karel Kovařovic. Le succès pragois et la recension publiée en Allemagne par Max Brod permirent à Janáček de signer un contrat avec Universal Verlag pour éditer la partition en allemand. Son directeur s’employa, avec succès, à faire représenter Jenůfa sur la scène du Hofoper de Vienne. Mais la date de la première, en février 1918, valut à l’opéra de se trouver au beau milieu d’une crise politique opposant nationalistes tchèques et allemands. Pouvait-on tolérer, durant la première guerre mondiale, la représentation, dans la Vienne allemande, d’un « opéra nationaliste tchèque » ? Son succès s’expliquait-il par une réelle qualité artistique ou n’était-il qu’une arme politique et le symptôme de tensions politiques insolubles ?
« Archaïscher Torso Apollos » (Torse archaïque d’Apollon) : un poème intraduisible ?
Authors: Macher Daniel
Published: January 2021

À partir de l’étude du poème « Archaïscher Torso Apollos », cette contribution propose une réflexion sur la langue poétique de Rilke, sur sa stratification étymologique et sémantique, ainsi qu’une réflexion sur la possibilité ou l’impossibilité de la traduire. En s’appuyant sur les termes Bug et Sturz, plus énigmatiques et riches qu’il n’y paraît au premier abord, l’article revient sur les choix opérés par six traducteurs francophones différents, et montre comment traduction et interprétation s’interpénètrent. Une traduction raisonnée de ces deux termes fait en effet ressortir avec netteté une vision de l’œuvre d’art plastique qui va dans le sens d’une poétique de la surface, conforme à la vision rilkéenne. Une dernière traduction du poème, qui tient compte des éléments sémantiques ici dégagés, vient clore le propos.
Schriftraum Diaspora: Die moderne Ästhetik der ewigen Wanderschaft bei Stefan Zweig
Authors: Paumgardhen Paola
Published: January 2021

Dieser Beitrag bespricht die Werke Stefan Zweigs, die ausdrücklich jüdische Thematik haben. In diesen Werken entwickelt Zweig aus seinem Konzept der Diaspora den Raum einer alternativen Ordnung, die ein pazifistisch übernationales Zusammenleben zusammen mit europäischer Modernität ermöglichen soll.
Cutting Edge: Hypoxia-Induced Ubc9 Promoter Hypermethylation Regulates IL-17 Expression in Ulcerative Colitis
Authors: Kumar Ritesh , Singh Amir Kumar , Starokadomskyy Petro , Luo Weibo , Theiss Arianne L. , Burstein Ezra , Venuprasad K.
Published: January 2021

Dysregulated IL-17 expression is central to the pathogenesis of several inflammatory disorders, including ulcerative colitis. We have shown earlier that SUMOylation of ROR-γt, the transcription factor for IL-17, regulates colonic inflammation. In this study, we show that the expression of Ubc9, the E2 enzyme that targets ROR-γt for SUMOylation, is significantly reduced in the colonic mucosa of ulcerative colitis patients. Mechanistically, we demonstrate that hypoxia-inducible factor 1α (HIF-1α) binds to a CpG island within the Ubc9 gene promoter, resulting in its hypermethylation and reduced Ubc9 expression. CRISPR–Cas9-mediated inhibition of HIF-1α normalized Ubc9 and attenuated IL-17 expression in Th17 cells and reduced diseases severity in Rag1−/− mice upon adoptive transfer. Collectively, our study reveals a novel epigenetic mechanism of regulation of ROR-γt that could be exploited in inflammatory diseases.
IL-38 Ablation Reduces Local Inflammation and Disease Severity in Experimental Autoimmune Encephalomyelitis
Authors: Huard Arnaud , Do Hoai Nam , Frank Ann-Christin , Sirait-Fischer Evelyn , Fuhrmann Dominik , Hofmann Martine Catharina Josephine , Raue Rebecca , Palmer Gaby , Brüne Bernhard , de Bruin Natasja , Weigert Andreas
Published: January 2021

IL-38 is an IL-1 family receptor antagonist that restricts IL-17–driven inflammation by limiting cytokine production from macrophages and T cells. In the current study, we aimed to explore its role in experimental autoimmune encephalomyelitis in mice, which is, among others, driven by IL-17. Unexpectedly, IL-38–deficient mice showed strongly reduced clinical scores and histological markers of experimental autoimmune encephalomyelitis. This was accompanied by reduced inflammatory cell infiltrates, including macrophages and T cells, as well as reduced expression of inflammatory markers in the spinal cord. IL-38 was highly expressed by infiltrating macrophages in the spinal cord, and in vitro activated IL-38–deficient bone marrow–derived macrophages showed reduced expression of inflammatory markers, accompanied by altered cellular metabolism. These data suggest an alternative cell-intrinsic role of IL-38 to promote inflammation in the CNS.
The Impact of Covid-19 Pandemic on the Preventive Services in Qatar
Authors: Al-Kuwari Mohamed Ghaith , Abdulmalik Mariam Ali , Al-Mudahka Hamad Rashid , Bakri Ahmad Haj , Al-Baker Wadha Ahmed , Abushaikha Shaikha Sami , Kandy Mujeeb Chettiyam , Gibb John
Published: January 2021

Background

In March 2020, Qatar started reporting increased numbers of COVID-19 cases. At that stage, containment measures were put in place. The health authority in Qatar developed an emergency action plan to respond to the outbreak with the Primary Health Care as the main component of that response and suspended all non-urgent services including preventive health services. The aim of the retrospective analysis to measure the Impact of COVID-19 on the preventive services provided in Qatar.

Methods

A retrospective data analysis was conducted for all the preventive services utilization volume across the 27 PHCC health centres from the 1st of January 2017 to the 31st of July 2020.

Results

With 17,012 no-show appointments, well-baby and Immunization services utilization demonstrated a reduction of 40% in May and started to come back to volumes higher than expected in June. The breast cancer and colorectal cancer screening programmes expected volumes demand has dropped by 100% in comparison to 2017 demand due to their respective appointments’ cancelation. Wellness services only met 20% of its projected utilization in April, however, the services picked up in June.

Conclusion

These findings will guide the public health policymakers to understand the effects COVID-19 on preventive services and the risk of having an increased number of outbreaks for childhood communicable disease, cancer cases with delayed diagnosis due to the screening services suspension. In addition, the plan will address the increased number of sedately behaviour due to the service's reduced utilization of wellness services.
Spontaneous Spinal Epidural Hematoma
Authors: Joga Pavan Pralobh , Nittala Pramod Philip , Mishra Anindita , Nyapathy Vinay
Published: January 2021

Spontaneous spinal epidural hematoma (SSEH) is a rare condition with an incidence of 0.1 in 100,000 population. These are usually seen in the lumbar region in patients above 40 years and in the cervical and dorsal spine in younger patients. Posterior or dorsal epidural hematomas are more common than ventral hematomas. Patients present with sharp pain in the neck or back with or without neurological deficit. We present a case of a 20-year-old male who presented with quadriparesis and bowel and bladder incontinence for 5 days. No history of trauma or other aggravating factors were present. Magnetic resonance imaging revealed a posterior epidural hematoma with cord compression and edema. Patient underwent surgery and hematoma was evacuated. Patient symptoms improved gradually. Because of the severe preoperative neurological deficit and delay in surgery, patient had mild residual neurological deficit in the early post op period, which resolved over a period of two months
Traumatic Lumbar Spondylolisthesis
Authors: Farooque Kamran , Kar Santanu
Published: January 2021

The aim of the study was to review published literature on traumatic lumbar spondylolisthesis. Traumatic spondylolisthesis of the lumbosacral region is a relatively rare but serious spinal injury necessitating careful clinico-radiological evaluation and management for a successful outcome. Limited literature is available to date to guide clinicians to treat the injury comprehensively. This article analyses the published literature and promulgates an evidence-based management plan for this injury. PubMed, Cochrane, Scopus, Google Scholar databases were searched using the keywords “traumatic lumbar” AND “spondylolisthesis” following PRISMA guidelines. In total, 118 relevant articles were considered for full-text review; among them, 68 articles were finally selected for the analysis. In each article, the pathomechanism; clinical and radiological features; classifications; indications for nonoperative and operative management; operative approaches, techniques, and rehabilitation; and long-term outcomes were analyzed. Traumatic lumbar spondylolisthesis is high-energy spine trauma requiring thorough evaluation. Radiographs are the initial investigation technique used in the emergency department, computed tomography scans define the bony details of the injury, and magnetic resonance imaging is important for deciding the treatment protocol depending on the disc injury. Decompression and instrumented fusion are the standard treatment protocol. A satisfactory outcome is to be expected in the majority of cases.
Performance of Deep Transfer Learning for Detecting Abnormal Fundus Images
Authors: Yu Yan , Chen Xiao , Zhu XiangBing , Zhang PengFei , Hou YinFen , Zhang RongRong , Wu ChangFan
Published: January 2021

Purpose:

To develop and validate a deep transfer learning (DTL) algorithm for detecting abnormalities in fundus images from non-mydriatic fundus photography examinations.

Methods:

A total of 1295 fundus images were collected to develop and validate a DTL algorithm for detecting abnormal fundus images. After removing 366 poor images, the DTL model was developed using 929 (370 normal and 559 abnormal) fundus images. Data preprocessing was performed to normalize the images. The inception-ResNet-v2 architecture was applied to achieve transfer learning. We tested our model using a subset of the publicly available Messidor dataset (using 366 images) and evaluated the testing performance of the DTL model for detecting abnormal fundus images.

Results:

In the internal validation dataset (n = 273 images), the area under the curve (AUC), sensitivity, accuracy, and specificity of DTL for correctly classified fundus images were 0.997%, 97.41%, 97.07%, and 96.82%, respectively. For the test dataset (n = 273 images), the AUC, sensitivity, accuracy, and specificity of the DTL for correctly classifying fundus images were 0.926%, 88.17%, 87.18%, and 86.67%, respectively.

Conclusion:

DTL showed high sensitivity and specificity for detecting abnormal fundus-related diseases. Further research is necessary to improve this method and evaluate the applicability of DTL in community health-care centers.
Prevalence of Refractive Error and Visual Impairment among Rural Dwellers in Mashonaland Central Province, Zimbabwe
Authors: Tagoh Selassie , Kyei Samuel , Kwarteng Michael Agyemang , Aboagye Evans
Published: January 2021

Purpose:

To determine the prevalence of refractive error and visual impairment in a rural population of Zimbabwe.

Methods:

This community-based, cross-sectional study used a multi-stage sampling to select the participants from households in four communities within three rural districts in Mashonaland Central Province. Participants' demographic data were collated, and their presenting visual acuity (VA) was measured using the logMAR E chart. Clinical refraction was preceded by an anterior segment and posterior segment eye examinations. Visual impairment was defined as presenting VA worse than 6/12 (0.3 logMAR) in the better eye. Descriptive statistics were presented as frequencies.

Results:

A total of 519 participants were involved in this study. Their ages ranged from 5 to 100 years (mean age = 50.94; standard deviation ± 21.12 years). Out of the 519 participants, 233 (44.9%) were male, and 286 (55.1%) were female. The prevalence of visual impairment was 56.8% (95% confidence interval [CI]: 55.7–67.2), and blindness was 13.1% (95% CI: 11.2–17.6). The prevalence of near visual impairment based on presenting near VA (N = 408) was 78.6% (95% CI: 78.1–85.4). The two most common causes of visual impairment were uncorrected refractive errors (UREs) (54.2%) and cataract (24.8%). The most common cause of blindness was cataract (41.2%). Hypermetropia (56.9%) was the most common refractive error.

Conclusions:

A high burden of visual impairment due to UREs and cataracts was observed among the rural dwellers of Zimbabwe. Public health education, access to refractive error services, and cataract surgery are necessary to mitigate this high burden of visual impairment.
Re-Endothelialization of Bare Stroma after Descemet's Detachment Due to Macroperforation During Deep Anterior Lamellar Keratoplasty
Authors: Ashena Zahra , Nanavaty Mayank A
Published: January 2021

Purpose:

To report a case with spontaneous re-endothelialization of bare stroma after subtotal detachment of Descemet's membrane (DM) due to macroperforation during deep anterior lamellar keratoplasty (DALK).

Methods:

Case report.

Results:

A 64-year-old patient underwent DALK for deep stromal scarring secondary to herpetic keratitis. During manual dissection, DM macroperforation occurred, and this was successfully managed intraoperatively and postoperatively. The DM with host posterior stroma remained attached for 10 months when it detached from the bare donor stroma. The cornea remained clear, with uncorrected distance visual acuity (UCVA) of 0.17 logMAR. After graft suture removal 30 months later, he was noted to have regular astigmatism and cataract for which he underwent phacoemulsification with toric intraocular lens implantation. Twenty-four months following his cataract surgery and 58 months following his DALK, his UCVA remains 0.17 logMAR and the cornea remains clear with no evidence of edema. His average specular count at 58 months was 1296 cell/mm2.

Conclusion:

This case shows a very good visual outcome with clear cornea at 58 months despite of large DM detachment which happened 10 months following manual DALK with intraoperative macroperforation.
Long-Term Intraocular Pressure Changes after Pars Plana Vitrectomy
Authors: Omidtabrizi Arash , Ghavami Vahid , Shafiee Masoud , Bayani Razieh , Banaee Touka
Published: January 2021

Purpose:

To investigate the long-term changes of intraocular pressure (IOP) after pars plana vitrectomy (PPV).

Methods:

This was a retrospective historical cohort study. Patients with a history of vitrectomy in one eye by a single surgeon were enrolled. IOP of the operated eye was compared to the fellow eye. Previous scleral buckling, IOP rise due to surgical/anatomic complications, silicone oil (SO) emulsification, and contralateral ocular hypertension/glaucoma at recruitment were exclusion criteria. “Significant IOP rise” (>6.0 mmHg) and development of open angle glaucoma (OAG) were the main outcome measures.

Results:

Two hundred and twenty-five eyes were included. Mean and median follow-up duration were 20.6 and 9.0 months, respectively. Mean baseline IOP and mean final IOP were 13.53 ± 3.75 mmHg and 16.52 ± 6.95 mmHg, respectively (P < 0.001). Forty-three patients developed “significant IOP rise” with no statistically significant relation to the indication of vitrectomy, the postoperative lens status, and number of vitrectomies (P = 0.410,P= 0.900, andP= 0.160, respectively). SO injection raised the probability of IOP rise in the long-term (P = 0.028). OAG occurred in 17 patients (7.5%) with no association to SO tamponade (P = 0.840). “Significant IOP rise” and OAG occurred in 3 and 1 control eyes, respectively, significantly lower than the rates in study eyes (P < 0.001).

Conclusion:

Mean IOP slightly rose in the long-term after PPV. SO tamponade was associated with IOP rise in the long-term but not with the incidence of OAG. Both IOP rise and OAG were more probable after vitrectomy.
Synchronous Dual Malignancies
Authors: Shah Aastha , Shivhare Vinay , Rath Satyajeet , Anand Dinesh , Shah Isha , Shah Rajal , Suryanarayan U.
Published: January 2021

Synchronous cancers are defined as two or more primary cancers diagnosed in the same patient at the same time or within 6 months of diagnosis of each other. The diagnosis of multiple primary malignancies is not uncommon. A 70-year-old male reported to our hospital with chief complaints of change in voice and difficulty in swallowing solid food for 2 months accompanied anorexia since 20 days. The patient revealed occasional consumption of alcohol for 3 years and bidi smoking for 50 years (10 bidis per day). The patient was conscious, cooperative, and well oriented to time, place and person with an Eastern Cooperative Oncology Group of 0. On physical examination, the oral cavity and oropharynx were unremarkable. Direct laryngoscopy revealed ulceroproliferative growth in right-sided vallecula, right-sided aryepiglottic fold, right side arytenoid and pyriform sinus, and right vocal cord. Biopsy from this growth turned out to be poorly differentiated squamous cell carcinoma. Computed tomography (CT) scan of the neck and thorax revealed 1.5 cm × 2.6 cm heterogeneously contrast enhancing lesion involving right aryepiglottic fold, pyriform fossa, posterior hypopharyngeal wall, and posterior aspect of both false vocal cords. Few subcentimeter lymph nodes were noted in right side Level II. The CT scan also showed some mass lesion abnormality in the upper section of liver images which could not be properly made out. Hence, triple-phase CT scan of the liver was done which to a great surprise showed 7.7 cm × 6.5 cm × 5.5 cm lesion in segment V and VIII, it showed enhancement on arterial phase, became prominent on portovenous phase and a delayed phase washout. Similar lesion measuring 4.4 cm × 4.1 cm was seen in segment VIII of liver; which was diagnosed radiologically as a multicentric hepatocellular carcinoma. Serum alpha fetoprotein was markedly elevated to a value of 28,600 ng/mL. A multidisciplinary tumor board discussion was done, and an intense literature review was done, and a decision was taken keeping in mind the overall performance score of the patient to commence with a high palliative radiotherapy for laryngeal cancer to a dose of 45 Gray in 15 fractions at a dose of 3 Gray per fraction and tablet tamoxifen at a dose of 60 mg/day till the end of radiation followed by switching over to tablet sorafenib. The patient ultimately developed uremia due to liver failure and died. The patient survived for a period of 3 months from the time of diagnosis of malignancy. Such cases need a meticulous approach for the diagnosis as well as treatment approaches. Keeping in mind the general condition of the patient and available therapeutic options, a patient-based specific approach could be developed.
Tubercular Rheumatism - Poncet's Disease
Authors: Kumar Abhinav , Singh Ashish Kumar , Bansal Priya , Bansal Rohit
Published: January 2021

Poncet's disease is a rare form of tuberculosis (TB). It is described as a hypersensitivity reaction of extra-articular TB, which manifests as acute-onset non-destructive polyarthritis of large joints. It resolves completely on anti-tubercular therapy. We describe a case of a young female patient who presented with symmetrical polyarthritis on a background of tubercular lymphadenitis. The workup for rheumatological diseases was negative. A diagnosis of Poncet's disease or tubercular rheumatism was made by exclusion. There was complete resolution of symptoms of joint disease following anti-tubercular therapy. Poncet's disease should be kept under suspicion in TB endemic areas while investigating patients of arthritis. In a resource-limited setting, in patients with TB, the response of coincident inflammatory arthritis to anti-tubercular therapy may be first observed, before subjecting them to further investigations and/or empirical therapy.
The spectrum of uveal effusion syndrome, medical therapy, and surgical treatment
Authors: Anguita Rodrigo , Marquez Juan Pablo , Roth Janice , Salinas Alejandro , Moya René
Published: January 2021

Aims:

The aim of the study is to describe and evaluate the clinical features, multimodal imaging, differential diagnoses, treatment options, and visual outcomes in patients with diagnosis of uveal effusion syndrome (UES).

Materials and Methods:

This was a retrospective, observational case series of patients with diagnosis of UES. Variables analyzed included age, gender, medical history, initial and final best-corrected visual acuity (BCVA), clinical features, type of treatment, and follow-up.

Results:

We report three cases, consisting of 2 males and 1 female, aged 37, 58, and 72 years with the diagnosis of UES. One patient was treated with medical therapy (acetazolamide) and the other two were submited to surgical treatment including one case of two-thirds thickness sclerotomy and one case with subscleral sclerectomy. All cases had complete resolution of subretinal fluid (SRF). BCVA improved in two cases, while there was no improvement of BCVA in one case due to outer retina atrophy as a consequence of chronic SRF.

Conclusions:

The diagnosis of UES still remains a challenge for a clinician. It is essential to know the clinical features differential diagnosis and be familiarized with the different therapeutic approaches to establish accurate diagnosis and treatment.
Probability distribution of heavy rainfall and determination of IDF in the city of Caruaru – PE
Authors: Mendes Kevin Matheus Correia , Oliveira Aline Lima de , Alcântara Lucas Ravellys Pyrrho de , Alves Adriana Thays Araújo , Santos Neto Severino Martins dos , Coutinho Artur Paiva , Montenegro Suzana Maria Gico Lima , Soares José Moura , Antonino Antonio Celso Dantas
Published: January 2021

In the design of hydraulic engineering works, the estimation of project precipitation is fundamental. Rain forecasting depends on several factors, which makes estimating it simpler with stochastic processes. In this sense, the distributions of Gumbel (GUM), Log-Normal two-parameter (LN2P), Generalized Extreme Value (GEV), Fréchet with two and three parameters (FRE2P and FRE3P), Weibull with two and three parameters (W2P and W3P), Gamma (GAM2P), and Pareto with two and three parameters (PAR2P and PAR3P) were evaluated to the annual maximum daily precipitation (AMDP) adjustment in the city of Caruaru (Pernambuco´s Agreste). A series of AMDP was used, based on data obtained from the National Water Agency (Agência Nacional de Águas - ANA). Anderson Darling (AD), Kolmogorov-Smirnov (KS) and Pearson Chi-square (χ2) adherence tests, and the determination coefficient (R²) were used to assess the adherence quality of the distributions. The Likelihood Method presented a better fit quality than the Moment Method. The GEV distribution obtained the best results for the AD test in both methods to estimate the parameters. Among the adherence tests used, the AD test was considered the most restrictive. To verify the quality parameters’ fitness to the IDF relations, the Willmott performance coefficient was used. For all distributions employed in this study, Willmott performance coefficients presented values above 0.99, giving a perfect fit of IDF relations with determination coefficients close to 1.0.
Probability of rainfall for the city of Cruzeiro do Sul, Acre, Brazil
Authors: Silva Jefferson Rodrigues dos Santos , Taveira Matheus Kucmanski , Serrano Rodrigo Otávio Peréa , Mesquita Anderson Azevedo , Moreira José Genivaldo do Vale
Published: January 2021

Due to randomness in the occurrence of hydrological phenomena, the estimation of probable rain precipitation in a given region is important in assisting decision-making. This work aimed to adjust the probabilistic model of the Gamma distribution to the monthly and annual rainfall totals recorded in the city of Cruzeiro do Sul, Acre, for the period between 1970 and 2019, in addition to estimating the expected values at different probability levels. Using the maximum likelihood method, the distribution parameters were estimated, with adherence ratified by the Kolmogorov-Smirnov test. The results showed that the Gamma distribution was adequate to adjust the data; the region has two well-defined periods in its rainfall pattern; the mean precipitation values recorded in the locality are between 25% and 40% of probability. Finally, probable rainfall values were presented at different probability levels for the city of Cruzeiro do Sul.
Physiological responses of inoculated and uninoculated peanuts under saline stress
Authors: Lima Antonio Fabio da Silva , Santos Max Ferreira dos , Oliveira Matheus Lima , Sousa Geocleber Gomes de , Mendes Filho Paulo Furtado , Luz Lucas Nunes da
Published: January 2021

This work evaluated the effects of water salinity on the physiological indices in inoculated and non-inoculated peanut plants. The study was carried out in a protected environment at the seedling production unit (UPMA) at Campus das Auroras, at the University for International Integration of the Afro-Brazilian Lusophony (UNILAB), Redenção, Ceará. The experimental design used was in a completely randomized (CRD), with treatments in a factorial arrangement, 5x2, referring to the five salinity levels of the irrigation water - CEa: 0.5, 1.5, 3, 4.5, and 6.0 dSm-1, and inoculated and non-inoculated plants with a mix of rhizobia SEMIA 630, lot 0810, and SEMIA 6144, lot 0312, from Bradyrhizobium sp., isolated, with four replications. Recommended fertilization was done for phosphorus (62.5 kg ha-1 of P) and potassium (50 kg ha-1 of K) to supply the nutritional needs of the plants. The nutritional effect caused by symbiosis with Bradyrhizobium sp. favored inoculated plants to present greater tolerance to salt stress. The availability of nitrogen collaborated to increase the efficiency of plant physiological mechanisms. Uninoculated plants, even with a higher amount of chlorophyll and CO2, were not efficient in the photosynthetic rate. Saline stress affected photosynthesis, transpiration, stomatal conductance, internal CO2 concentration, water use efficiency, and chlorophyll; however, with less intensity when inoculated with Bradyrhizobium sp. The increase in salinity on irrigation water increased the leaf temperature.
Analysis of the Presence of Criminal Offenses in the Field of the Shadow Economy in Serbia
Authors: Knezevic Snezana , Cvetkovic Dragan , Micovic Marija , Mitrović Aleksandra , Milojević Stefan
Published: January 2021

The shadow economy offenses are a group of offenses with a wide variety of manifestations occurring in almost all areas of economic activity. The shadow economy, as a special form of economic crime, is increasingly disrupting the smooth functioning of the economy, but also causing significant material damage to society. The Republic of Serbia is making efforts to curb the shadow economy, which significantly reduces its budget revenue. In this paper, after conceptual determination of the shadow economy phenomena in the literature review, determining the causes and manifestations of crimes in the field of the shadow economy, we will analyze their volume, structure and dynamics, as well as their participation in the mass of total, i.e. economic crime in the Republic of Serbia from 2006 to in 2018. The aim of this paper is to emphasize the extreme importance of more appropriate involvement of competent authorities in order to combat this type of crime in modern economies by analyzing the causes and effects as well as the dynamics of this phenomenon.
Controle do risco, imputação objetiva e legalidade penal: um ensaio sobre os requisitos de legitimidade das técnicas de reenvio no Direito Penal
Authors: Amaral Rodrigo José dos Santos
Published: January 2021

O presente artigo versa sobre questões que envolvem o princípio nullum crimen sine lege e as técnicas de reenvio no direito penal, que representam modernamente um ponto de aparente tensão. Partindo da premissa que todo poder estatal deve ser justificado para ser considerado jurídico, investiga-se os fundamentos do princípio da legalidade penal em um Estado de Direito. Para estabelecer critérios de aferição de legitimidade nos tipos penais que contêm técnicas de reenvio, utiliza-se a teoria da imputação objetiva como parâmetro de comparação. Este estudo foca nos aspectos formais da redação legal dos tipos penais, ficando em aberto o conteúdo da norma remetida.
Determinação judicial da pena no crime de afastamento de licitante (art. 95 da L. 8.666/93): ne bis in idem e consequências extratípicas do delito
Authors: Leite Alaor , Teixeira Adriano
Published: January 2021

A partir de um caso concreto, investiga-se se, no contexto do delito previsto no art. 95 da L. 8.666/93, pode a formalização de ajuste em negócio jurídico, garantido por nota promissória, que visa ao afastamento de outro licitante por meio de oferecimento de vantagem, ser considerada como circunstância desfavorável na determinação judicial da pena-base (art. 59 do Código Penal). Para a resposta, que resultará negativa, analisam-se as questões do ne bis in idem e da relevância das consequências extratípicas do delito na determinação judicial da pena, especialmente na fixação da pena-base.
Multiple Cavernous Malformations: A Case Report
Authors:   Neurosurgeon, Neurosurgery Service Coordinator Kennedy´s Hospital, Bogotá, Colombia, Oscar Fernando Gutiérrez Rincón , Santiago Moreno García ,   Hospital doctor of Neurosurgery, Kennedy's hospital, Bogotá, Colombia, Maria José Hoyos Bedoya ,   Medical student, National University of Colombia, Colombia, Sarah Juliana Builes Cerón ,   Medical student, National University of Colombia, Colombia
Published: January 2021

Cavernous malformations are alterations in the conformation of arteries and veins that can be found both intracranial and intraspinal; however, the variables are very important for the diagnosis and treatment of patients. The main clinical manifestation is epileptic seizures in cases of bleeding, but in many cases they are asymptomatic in the course of life and are found as findings related to neuroimaging studies for other reasons. It is more common to find unique lesions, but in cases of multiple lesions it is likely to find an autosomal dominant hereditary factor, which makes the person more likely to convulse due to sporadic bleeding. Medical management focuses on the clinical presentation and management of epileptic seizures, while surgical management takes into account the size, location and bleeding. Below is a clinical case that represents one of the different clinical manifestations and the approach that was given in said patient.
Glomus Tumor of Uncertain Malignant Potential: A Rare Case Report
Authors:   Department of Pathology, Gujarat Cancer and Research Institute Ahmedabad, India, Shailee Mehta , Ritwika Dabral ,   Department of Pathology, Gujarat Cancer and Research Institute Ahmedabad, India, Priti Trivedi ,   Department of Pathology, Gujarat Cancer and Research Institute Ahmedabad, India
Published: January 2021

Glomus tumor is usually a small, benign tumor and typically occurs in the dermis or subcutis or soft tissues of the extremities and rarely in the visceral locations. Its bronchopulmonary origin is exceedingly rare clinical condition. The current case reported a 51-year-old male with dyspnea on exertion and obstructive pneumonia; he had a glomus tumor which has large size, deep location and exhibits an infiltrative margin as well as atypical mitotic figures. These characteristic suggests malignant behavior. Therefore diagnosis of glomus tumor of uncertain malignant potential was favored. Recently, the histopathological diagnostic criteria for malignant glomus tumors were defined in the WHO classification of soft tissue and bone tumors 4th edition. Here we also reviewed the literature on primary bronchopulmonary glomus tumors with special attention to the current concept of malignancy grade estimation.
Plummer-Vinson Syndrome as an Unusual Cause of Dysphagia and Iron Deficiency Anemia in a 6-year-old Boy
Authors:   Department of Pediatrics, Ped Mind Institute, Germany, Stefan Bittmann , Elisabeth Luchter ,   Department of Pediatrics, Ped Mind Institute, Germany, Elena Moschüring-Alieva ,   Department of Pediatrics, Ped Mind Institute, Germany, Gloria Villalon ,   Department of Pediatrics, Ped Mind Institute, Germany
Published: January 2021

We report the case of a 6-year-old boy with dysphagia and iron deficiency anemia with an Hb of 5.6 g/dl leading the diagnosis of Plummer-Vinson syndrome. An esophageal stenosis of 4 mm diameter near the upper esophageal sphincter was found. Balloon dilatation and iron substitution cured the problem. Pediatricians should keep in mind that the rare entity of Plummer-Vinson syndrome in unclear cases of dysphagia.
Myoclonus Considerations on Their Classification and Treatment
Authors:   Department of Neurology, Gustavo Aldereguía Lima Teaching Hospital, Cienfuegos, Cuba, Julio López Argüelles , Leydi M Sosa Aguila ,   Department of Neuropsychology, Gustavo Aldereguía Lima Teaching Hospital, Cienfuegos, Cuba, Aleima B Rodríguez Carvajal ,   Centre of Genetics, Paquito González Cueto Teaching Hospital, Cienfuegos, Cuba
Published: January 2021

Myoclonus is defined as involuntary, sharp and short-term movements of one or more muscular groups, stemmed from any structure of the central nervous system. Even though the study the myoclonus to motivated great quantity of scientific articles is not known with precision the physiopathological mechanisms that produce them. There are numerous classifications of the myoclonus that consider semiologic aspects, etiological, nosological, or physiological. Within them it takes on great importance the cortical myoclonus which occurs after the cortical origin of discharge transmitted through the pyramidal way
Red Spots on the Palms
Authors:   Health Center of Guriezo, Cantabria, Servicio Cantabro de Salud (Public Health System in Cantabria), Spain, Salvador Labrador , Sergio Vano-Galvan ,   Health Center of Guriezo, Cantabria, Servicio Cantabro de Salud (Public Health System in Cantabria), Spain
Published: January 2021

A 36-year-old male presented at our clinic by early autumn for pruritus and a sudden spotted rash on the dorsum, palms and soles with no fever.
Eighteen Questions for the Better Understanding of RADS
Authors:   Colleges of Public Health & Medicine, University of South Florida Health Sciences Center, USA, Stuart M Brooks
Published: January 2021

RADS are typically associated with a solitary inhalation exposure to a very high concentration of an irritant gas, vapor, aerosol or fume. Evolution of asthma-like symptoms and airway hyperresponsiveness are consequences Prompt medical assistance is needed within the first 24 hours. The manuscript unveils suggested sequences of RADS’ pathogenesis. The airway injury causes sloughing off of damaged and dead airway cells. Putatively, escaping intracellular molecules, from dead and damaged cells, enter the extracellular space as damage-associated molecular patterns (DAMPs); they are also known as “alarmins.” The molecules promote an inflammatory response and orchestrate cellular repair and tissue healing. Different mediators and regulatory intermediaries, chemokines and cytokines, arachidonic acid products, soluble growth factors, prostaglandins, and matrix components take part in regenerative process. Lung macrophages provide clean-up and repair services: and, they impact airway hyperresponsiveness. Metalloproteinases and extracellular matrix improve the epithelial-tomesenchymal matrix. Airway wall thickening, subepithelial fibrosis, mucus metaplasia, myofibroblast hyperplasia, muscle cells hyperplasia and hypertrophy, and epithelial hypertrophy become features of the airway remodeling response.
Sclero-atrophic lichen of unusual siege that occurred during the Pregnancy
Authors:   Department of Dermatology, CHU Hassan II de Fez, Morocco, A Rasso , K Laamari ,   Department of Dermatology, CHU Hassan II de Fez, Morocco, S Benkirane ,   Department of Dermatology, CHU Hassan II de Fez, Morocco, A Oulhri ,   Department of Dermatology, CHU Hassan II de Fez, Morocco, H Baybay ,   Department of Dermatology, CHU Hassan II de Fez, Morocco, Z Douhi ,   Department of Dermatology, CHU Hassan II de Fez, Morocco, S Elloudi ,   Department of Dermatology, CHU Hassan II de Fez, Morocco, FZ Mernissi ,   Department of Dermatology, CHU Hassan II de Fez, Morocco
Published: January 2021

A 35-year-old women, without a significant pathological history, she reported the notion of lesions appearing when she was pregnant at 30 weeks of amenorrhea in the breasts, slightly itchy and evolving since one year.
PENGARUH BUDAYA ORGANISASI, KOMPENSASI DAN GAYA KEPEMIMPINAN TERHADAP KINERJA KARYAWAN DI PERUSAHAN ROKOK (PR). SUMBER BAROKAH
Authors: Pranatha Anodia Tegar , Qomari Nurul , Iman Nurul
Published: January 2021

Tembakau adalah salah satu komoditas paling penting di Indonesia.Produk utama dari tembakau yang banyak diperdagangkan adalah rokok. Tujuan yang hendak dicapai dalam penelitian ini adalah untuk menguji dan menganalisa tentang adanya pengaruh budaya organisasi, kompensasi dan gaya kepemimpinan terhadap kinerja karyawan pada Pr. Sumber Barokah di Sidoarjo. Penelitian ini dilakukan pengambilan data dilakukan dengan bertemu dengan pemilik Pr. Sumber Barokah, setelah itu menyamakan konsep penelitian yang akan diteliti di lokasi tersebut. Dan akhirnya untuk mendapatkan data angket peneliti menyebarkan pernyataan-pernyataan yang telah disediakan didalam kuesioner, kuisoner tersebut dibagikan pada 89 responden secara acak. Teknik pengambilan data ini menggunakan random sampling dari data tersebut dilakukan uji validitas, reliabilitas, uji linear berganda Uji f dan Uji t. Berdasarkan hasil pengujian maka dapat disimpulkan bahwa budaya organisasi, kompensasi dan gaya kepemimpinan secara bersama-sama (simultan) maupun secara masing-masing (parsial) memiliki pengaruh yang signifikan terhadap kinerja karyawan. Variabel kompensasi pada Pr. Sumber Barokah di Sidoarjo berdasarkan hasil penelitian pada analisis linear berganda terbukti menjadi variabel yang dominan.
PENGARUH KOMPENSASI, IKLIM KERJA DAN BUDAYA ORGANISASI TERHADAP KINERJA KARYAWAN CV. BAHARI TEKNIK GEDANGAN SIDOARJO
Authors: Alfitri Tyas Ayu , Musriha Musriha , Bramastyo RM
Published: January 2021

Penelitian ini bertujuan untuk menguji dan menganalisis pengaruh kompensasi, iklim kerja dan budaya organisasi terhadap kinerja karyawan CV. Bahari Teknik Gedangan Sidoarjo.Penelitian ini menggunakan teknik pengumpulan data yaitu observasi, wawancara dan kuisioner. Populasi penelitian adalah seluruh karyawan CV. Bahari Teknik Gedangan Sidoarjo, dengan sampel diambil dengan menggunakan sampling jenuh. Teknik analisis data pada penelitian ini menggunkan bantuan SPSS, dengan pengujian data yang digunakan dalam penelitian ini meliputi uji validitas, uji asumsi klasik, uji reabilitas dan analisis regresi linier berganda.Hasil penelitian menunjukkan bahwa secara simultan dan parsial kompensasi, iklim kerja dan budaya organisasi berpengaruh signifikan terhadap kinerja karyawan CV. Bahari Teknik Gedangan Sidoarjo. Sedangkan dari hasil pengujian regresi maka dapat disimpulkan bahwa variabel yang paling dominan berpengaruh terhadap kinerja karyawan CV. Bahari Teknik Gedangan Sidoarjo adalah iklim kerja, hal ini dikarenakan dengan adanya iklim kerja yang kondusif dan fasilitas yang cukup yang diberikan oleh perusahaan maka akan mempengaruhi peningkatan kinerja karyawan pada CV. Bahari Teknik Gedangan Sidoarjo.
PENGARUH SISTEM INFORMASI AKUNTANSI, GAYA KEPEMIMPINAN, DAN MOTIVASI KERJA TERHADAP KINERJA KARYAWAN PADA KANTOR POS JEMUR ANDAYANI SURABAYA
Authors: Nanda Suci Gustia , Mahsina Mahsina , Lestari Tr
Published: January 2021

Tujuan penelitian dari penelitian ini adalah untuk mengetahui pengaruh sistem informasi akuntansi, gaya kepemimpinan, dan motivasi kerja terhadap kinerja karyawan. Populasi pada penelitian ini adalah karyawan yang bekerja di perusahaan yang bergerak dibidang pelayanan jasa pada kantor pos jemur andayani Surabaya dan jumlah responden pada penelitian ini adalah 25 responden. Metode yang digunakan adalah metode kuantitatif metode analisis data menggunakan analisis regresi linier berganda dan proses menggunakan applikasi SPSS. Hasil penelitian menunjukkan bahwa secara parsial membuktikan bahwa gaya kepemimpinan berpengaruh positif terhadap kinerja karyawan. Sedangkan sistem informasi akuntansi dan motivasi kerja tidak berpengaruh positif terhadap kinerja karyawan.
AKUNTABILITAS PENGELOLAAN ANGGARAN PENDAPATAN DAN BELANJA DESA (Studi Kasus Desa Bluru Kidul Kecamatan Sidoarjo)
Authors: Saragih Ade Olivia , Rahman Arief , Lestari Tri
Published: January 2021

Penelitian ini membahas Akuntabilitas Pengelolaan Anggaran Pendapatan dan Belanja Desa (APBDes) dengan tujuan untuk mendeskripsikan Akuntabilitas Pemerintah Desa dalam Pengelolaan Anggaran Pendapatan dan Belanja Desa (APBDes) Tahun 2017. Penelitian ini dilakukan untuk mengetahui prinsip akuntabilitas mulai dari perencanaan, pelaksanaan, penatausahaan, laporan pertanggungjawaban. Pendekatan penelitian ini menggunakan kualitatif deskriptif. Hasil penelitian ini menunjukkan bahwa prinsip akuntabilitas dalam pengelolaan Anggaran Pendapatan dan Belanja Desa (APBDes) Tahun 2017 di desa Bluru Kidul Kecamatan Sidoarjo secara bertahap mulai dari tahap perencanaan, pelaksanaan, penatausahaan sampai pada tahap pelaporan dan pertanggung jawaban APBDes telah sesuai dengan Permendagri No.113 tahun 2014, namun pemerintah desa belum transparan terhadap masyarakat. sisi pengelolaan administrasi keuangan dalam pertanggunjawaban masih diperlukan adanya pembinaan dan pengawasan.
PENGARUH FAKTOR-FAKTOR AUDIT INTERNAL TERHADAP KINERJA STAF QUALITY CONTROL (Studi Kasus PT. Pabrik Kertas Tjiwi Kimia Tbk. di Sidoarjo)
Authors: Anggoman Aga Rifki , Masyhad Masyhad , Lestari Tri
Published: January 2021

Penelitian ini bertujuan untuk mengetahui Pengaruh Faktor-Faktor Audit Internal secara parsial dan simultan Terhadap Kinerja Staf Quality Control pada PT. Pabrik Kertas Tjiwi Kimia Sidoarjo. Variabel independen penelitian ini adalah profesionalisme, ruang lingkup dan independensi. Sedangkan untuk variabel dependen penelitian ini adalah kinerja staf quality control. Teknik pengumpulan data dilakukan menggunakan metode kuesioner. Data dianalisis menggunakan software SPSS 18.0. Persamaan regresi penelitian ini adalah regresi linier berganda dan teknik pengujian data meliputi uji validitas, uji reliabelitas dan uji asumsi klasik. Hasil penelitian ini menunjukan bahwa profesionalisme, ruang lingkup dan independensi audit internal berpengaruh positif signifikan terhadap kinerja staf quality control.
Платон и стоичко учење у богословљу Иполита Римског
Authors: Марковић Мирослав С.
Published: January 2021

Богословље Иполита Римског је веома сложено, учено, и прилично занимљиво. У овом чланку, аутор истиче два главна философска извора Иполитовог надахнућа — учење Платона и стоичко учење.
Бонифацијева мисионарска и реформаторска активност у Западној Европи
Authors: Мишковић Милош
Published: January 2021

Овај рад има за за­да­так да при­ка­же ми­си­о­нар­ску и ре­фор­ма­тор­ску де­лат­ност Бо­ни­фа­ци­ја, нај­зна­чај­ни­јег ан­гло­сак­сон­ског ми­си­о­на­ра у За­пад­ној Евро­пи. Ан­гло­сак­сон­ски ми­си­о­на­ри да­ли су ве­ли­ки до­при­нос про­це­су хри­сти­ја­ни­за­ци­је гер­ман­ских пле­ме­на. Бо­ни­фа­ци­је уз по­моћ Ри­ма и Фра­нач­ке др­жа­ве при­сту­па ми­си­ји хри­сти­ја­ни­за­ци­је па­ган­ских пле­ме­на; ме­ђу­тим, па­па ће му по­ве­ри­ти и за­да­так да ре­фор­ми­ше цркве­не ор­га­ни­за­ци­је у За­пад­ној Евро­пи. Има­ју­ћи про­тив­ни­ке у фра­нач­ком епи­ско­па­ту, Бо­ни­фа­ци­је реформу Фра­нач­ке Цр­кве ни­је мо­гао да из­ве­де у пот­пу­но­сти, али је за­хва­љу­ју­ћи ње­му по­ста­вљен те­мељ за чвр­шће по­ве­зи­ва­ње Рим­ске и Фра­нач­ке Цр­кве.
Верска настава у Србији: период од формирања Краљевине СХС до почетка Другог светског рата
Authors: Трајковић Марко
Published: January 2021

Циљ овог ра­да је да ука­же на спе­ци­фич­но­сти уво­ђе­ња Вер­ске на­ста­ве у Ср­би­ји из­ме­ђу два свет­ска ра­та. Пе­ри­од је по­де­љен на три це­ли­не у ко­ји­ма се оцр­та­ва­ју иза­зо­ви и на­по­ри др­жа­ве у по­гле­ду уни­фи­ка­ци­је, као и на­по­ри за уво­ђе­ње и очу­ва­ње Вер­ске на­ста­ве Пра­во­слав­не цр­кве на свим обра­зов­ним ни­во­и­ма. У пр­вој це­ли­ни освр­ће­мо се на по­ло­жај ко­ји је Вер­ска на­ста­ва има­ла у Кра­ље­ви­ни Ср­би­ји до ује­ди­ње­ња, као и на про­ме­ну по­зи­ци­је у но­во­о­сно­ва­ној др­жа­ви. Дру­га це­ли­на ука­зу­је на све ве­ће су­ко­бе из­ме­ђу „ли­бе­рал­них“ и „кле­ри­кал­них“ сна­га у дру­штву ка­да је реч о уре­ђе­њу про­све­те. Тре­ћа це­ли­на се од­но­си на пе­ри­од од 1929. го­ди­не и ко­нач­ног уни­фи­ко­ва­ња про­свет­не по­ли­ти­ке у Кра­ље­ви­ни Ју­го­сла­ви­је.
Penerapan Model Cooperative Learning Tipe Probing Prompting untuk Meningkatkan Hasil Belajar Kognitif Siswa Mata Pelajaran Fiqih
Authors: Salahudin Anas , Siregar Hariman Surya , Nurazizah Annisa
Published: January 2021

Learning Fiqh in class IV MI Hayatul Islam Cileat was monotonous which affected to lower cognitive learning outcomes. The purpose of this study was to determine whether the Probing Prompting type of Cooperative Learning can improve students' learning outcomes. This research was Classroom Action Research. The results of the mean score before using Probing Prompting was 57.72. In the first cycle, the teacher's activity was 79.99% while the second cycle was 89.99%. The students' activities in cycle I 79.99%, cycle II 89.99%. Student cognitive learning outcomes after using the Cooperative Learning model type Probing Prompting Learning cycle I 70.34 cycle II 82.27. The accomplishment in Cycle I 54.54%, Cycle II 95.45%. The study concluded that the Cooperative Learning type Probing Prompting model could improve student cognitive learning outcomes in fiqh subjects.