bluuebunny/crossref_metadata_2025 huggingface dataset:
Ministries on WhatsApp: gender, sensorialities and ethical-political transformations in the everyday life of evangelical women
Authors: Mochel Lorena
Published: October 2023

Abstract Recent literature on the political participation of Pentecostal evangelicals in Brazil has drawn attention to the transformations caused by their use of digital media. To broaden this debate, in this article I describe the everyday use of the WhatsApp instant messaging program by prayer groups, shedding light on how disputes engaged by Pentecostal women have re-signified their pastoral careers and formed new evangelical collectivities. With the emergence of other ways of experiencing the intimacy provided by mobile devices, I reflect on religious connections established across images and sounds in WhatsApp groups, in addition to the digital impact on the dynamics of female religious authority and its transnational expansion.
El Poder de Nombrar Intelectuales Antirracistas Feministas Brasileñas en Plataformas Digitales
Authors: Josiowicz Alejandra J.
Published: October 2023

Resumen Este artículo examina la práctica de nombrar a mujeres intelectuales antirracistas como una forma de activismo digital feminista en Brasil, en tuits que hacen referencia a Carolina Maria de Jesus y Lélia González. El análisis combina las herramientas de las humanidades digitales feministas decoloniales, la historia intelectual y lo que se ha denominado “lectura a distancia”, para estudiar el acto de nombrar como un conjunto de prácticas tecno-discursivas. Aborda la circulación transnacional de tuits, la emergencia y relevancia de los hashtags, los usuarios más mencionados y los temas con mayor tracción en las redes sociales. La principal conclusión es que las prácticas digitales de nombrar intelectuales feministas antirracistas brasileñas en Twitter son herramientas poderosas para crear y movilizar significados sociales que: (1) subvierten los cánones y jerarquías globales e intelectuales; 2) aprovechan las posibilidades técnicas de las plataformas digitales, pero en lugar de privilegiar la publicidad y la autopromoción van contra el determinismo de las plataformas y subrayan una lógica igualitaria; y (3) forman y mantienen identidades colectivas y solidifican contrapúblicos.
VIVÊNCIA ACADÊMICA, FORMAÇÃO UNIVERSITÁRIA, DESENVOLVIMENTO HUMANO: CONTRIBUIÇÕES DE VIGOTSKI AO ENSINO SUPERIOR
Authors: Garcia Wallisten Passos , Pan Miriam Aparecida Graciano de Souza
Published: October 2023

RESUMO Este estudo tem como objetivo desenvolver o conceito de vivência acadêmica, fundamentado no conceito de perejivânie (vivência) de Vigotski, como compreendido nas obras que pertencem à fase final de sua vida (Vigotski, 1934/2018a; Vygotski, 1934/2006a). No entendimento da vivência como unidade dinâmica da consciência, encontramos uma chave conceitual importante para a compreensão do desenvolvimento psicológico dos universitários. Evidenciamos que a relação dos estudantes com as práticas formativas no Ensino Superior produz vivências acadêmicas que mobilizam a consciência e orientam os sentidos sobre o que é ser estudante e profissional de uma determinada área, resultando em transformações que geram nos universitários novas formas de pensamento, sentimentos e posicionamentos diante da vida acadêmica. Desse modo, o conceito de vivência acadêmica constitui-se em uma importante ferramenta para a análise dos processos de sucesso e fracasso acadêmico, da qualidade das práticas formativas e das políticas de assistência e permanência estudantil por constituir-se como um indicador qualitativo da vida universitária.
Dying with end stage kidney disease: factors associated with place of death on a palliative care program
Authors: Rodrigues Ana Cunha , David Filipa , Guedes Rita , Rocha Céu , Oliveira Hugo M.
Published: October 2023

Abstract Introduction: End of life care of patients with end-stage kidney disease (ESKD) may be particularly challenging and requires the intervention of a specialized palliative care team (PCT). Objective: To characterize the population of ESKD patients referred to a PCT and evaluate the determinants of planned dying at home. Methods: We performed a retrospective observational cohort study of all patients with ESKD referred to our PCT between January 2014 and December 2021 (n = 60) and further characterized those with previously known ESKD regarding place of death (n = 53). Results: The majority of the patients were female and the median age was 84 years. Half of the patients were on conservative treatment, 43% were on chronic hemodialysis, and the remainder underwent hemodialysis on a trial basis and were subsequently suspended. Of those with previously known ESKD, 18% died at home and neither gender, age, cognition, performance status, comorbidities, CKD etiology, or treatment modality were associated with place of death. Anuria was significantly associated with dying at the hospital as was shorter time from dialysis suspension and death. Although not reaching statistical significance, we found a tendency towards a longer duration of palliative care follow-up in those dying at home. Conclusion: Dying at home is possible in a palliative domiciliary program regardless of age, gender, etiology of CKD, major comorbidities, and treatment modality. Anuria and shorter survival from RRT withdrawal may be limiting factors for planned dying at home. A longer follow-up by palliative care may favor dying at home.
Tensionamentos dos Rastros Historiográficos do Zouk Brasileiro
Authors: Navarro Ana Carolina , Buarque Isabela , Menegaldo Luciano
Published: October 2023

RESUMO Tensionamentos dos Rastros Historiográficos do Zouk Brasileiro – O artigo objetiva difundir informações a respeito do Zouk Brasileiro, buscando contribuir com a historicização de danças brasileiras por meio de uma reflexão crítica. Para isso, foram consultadas fontes bibliográficas (artigos, teses, dissertações, vídeos e reportagens) e registros de diários de campo. As análises evidenciam disputas a respeito dos pontos: 1) surgimento do ritmo musical e da dança; 2) utilização de movimentos básicos e competitivos; 3) processo de mercantilização; e 4) questões contemporâneas do corpo. Destaca-se que o trabalho se justifica pela necessidade de ampliação dos debates acerca das historiografias de dança no país.
Food access strategies implemented in Venezuela by a group of Venezuelans living in Cuiabá, Brazil
Authors: Vargas John Edinson Velásquez , Gugelmin Silvia Angela
Published: October 2023

Abstract The socio-political crisis in Venezuela has generated various problems, such as food insecurity, shortages of basic products and medicines, increased unemployment and massive migration to other countries in the region. To identify the strategies for access to food experienced by Venezuelan immigrants residing in Cuiabá-MT, Brazil. This research was conducted under the qualitative approach, this approach allowed us to investigate how was the impact regarding the access and consumption of food in Venezuela lived by Venezuelan immigrants residing in Cuiabá - Brazil, from the documentation, description and understanding of the experiences they face; 13 participants were included, the data collection technique used were individual interviews. Among the main findings was that most of the interviewees did not feel comfortable with the food they had in Venezuela, given the poor conditions of access and availability of food, many of them expressed perceptions of hunger and anguish due to the lack of food and these situations led them to seek better living conditions. The socio-political crisis in Venezuela that produced the lack of availability and access to food, generated strategies to ensure a permanent food supply within households where often these strategies are not in line with a healthy and adequate diet.
Harm reduction among strength training practitioners who consume steroids
Authors: Ferreira Túlio Cândido , Palma Alexandre , Pasquim Heitor Martins
Published: October 2023

Abstract This research analyzes the critical processes for harm reduction among steroid consumers, in the context of gyms in the metropolitan region of Goiânia, Goiás. The study subjects were selected using Snowball sampling. Content analysis was carried out from the transcription of fifteen interviews, and the exploration of the produced material led to the construction of four categories a posteriori. Actions-such as individual risk management, by self-experimentation to assess the product’s quality and self-medication in the form of post-cycle therapies, for example-were observed and, at the same time, processes that afford health protection, especially regarding the support networks and favorable socioeconomic position of this study’s participants. Structuring proactive, continuous, and integrated harm reduction actions that respond to steroid consumers’ health needs is considered important, as well as implementing strategies that overcome both the war on drugs approach and the merely pragmatic and individual approach to risk management.
Amblyomma sculptum ticks on a giant otter from the Brazilian Pantanal
Authors: Soresini Grazielle , Foerster Nathalie , Paiva Fernando , Mourão Guilherme , Leuchtenberger Caroline
Published: October 2023

Abstract The giant otter (Pteronura brasiliensis) is a semiaquatic carnivore and a top predator in the trophic chain, considered a sentinel of freshwater ecosystems. Ticks are common ectoparasites of worldwide distribution and potential vectors of diseases. In this study, we report the ectoparasitism by ticks on a giant otter carcass found during monitoring activity at the Negro River, that holds a viable population of this endangered species in the Brazilian Pantanal. A total of three tick specimens were collected: two adults were identified as Amblyomma sculptum and a nymph as Amblyomma spp. There is a lack of information about the health of free-ranging giant otters and this report contributes to elucidate some of the host-parasite relationships, although much more research is needed to expand the knowledge about which kinds of pathogens are circulating in the species, especially among those transmitted by ticks.
Tendência temporal da taxa de abandono e da cobertura da vacina tríplice viral no Brasil, 2014-2021
Authors: Moura Lívia de Lima , Neto Mercedes , Souza-Santos Reinaldo
Published: October 2023

Resumo Objetivo: analisar a tendência temporal da cobertura e da taxa de abandono da vacina tríplice viral no Brasil, nas Unidades da Federação (UFs) e grandes regiões nacionais, entre 2014 e 2021. Métodos: estudo ecológico de série temporal, sobre dados do Sistema de Informações do Programa Nacional de Imunizações e do Sistema de Informações sobre Nascidos Vivos; foram utilizados modelos de regressão por pontos de inflexão. Resultados: as coberturas vacinais anuais, no Brasil como um todo, estiveram abaixo de 95%, variando de 92,3% (2015) a 54,4% (2021); a segunda dose da vacina apresentou tendência temporal decrescente no período (variação média no período = -5,8; IC95% -10,5;-0,8); as tendências temporais foram estacionárias e decrescentes nas UFs; a taxa de abandono variou de 22,2% (2014) a 37,4% (2021). Conclusão: houve tendência de queda da cobertura vacinal e aumento da taxa de abandono, no Brasil como um todo e nas UFs.
Incidence and clinical decision making for the Wada test over one decade: 1997‐2007
Authors: Das Rohit R. , Alexopoulos Andreas V. , Loddenkemper Tobias
Published: October 2023

Purpose

The objective of this study was to review the percentage of Wada tests performed on patients with intractable temporal lobe epilepsy undergoing surgery at a single epilepsy centre over the last decade, and to identify clinical features which are more likely associated with decision making in favour of Wada testing.

Methods

We retrospectively reviewed all temporal lobe resections performed between 1997 and 2007 at the Cleveland Clinic Epilepsy Center.

Results

A total of 410 Wada tests were conducted on 777 patients undergoing temporal lobectomy (TL). Left temporal resection was performed in 55% of cases. The most frequent pathological diagnoses were hippocampal sclerosis (42%) and non‐specific gliosis (26%). Overall, Wada test frequency in patients undergoing presurgical evaluation decreased over time. In 1997, 47 of 58 (81%) TL patients underwent Wada testing compared to 11 of 76 (14.4%) in 2007. Patients with left temporal lobe epilepsy, and/or those referred for subdural electrode placement, were significantly more likely to undergo Wada testing. The most common types of surgery were anteromedial temporal resection with removal of mesial structures (59%) and temporal resection without mesial structure removal (32%). Patients with left temporal epilepsy and Wada testing were significantly more likely to undergo resection of mesial cortex.

Discussion

Wada testing has declined over the last decade in this single centre study. Patients with left, likely dominant, temporal lobe epilepsy and those with subdural evaluations were more likely to undergo Wada testing. We speculate that the emergence of alternative noninvasive language lateralization techniques, along with concerns about the reliability of results and awareness of complication risks, are major reasons for the decline.
Statistical analysis of transcallosal propagation of spikes arising from the mesial frontal area
Authors: Umeoka Shuichi C. , Lüders Hans O. , Sangani Masoud Abed , Turnbull John P.
Published: October 2023

Objective

To study the connections between bilateral mesial frontal (MF) regions.

Methods

We evaluated synchrony of spikes, recorded by subdural electrodes, arising from bilateral MF regions using cross correlation in MF epilepsy. A seven‐year‐old boy with intractable daily bilateral asymmetric tonic seizures and a normal MRI was investigated. To confirm the lateralization of epileptogenicity, subdural electrodes were implanted bilaterally. Only spikes of an amplitude of 400 μV or more were analyzed.

Results

Of 92.4% (194/210) of the left MF spikes recorded for 30 minutes, an approximately synchronous spike was also detected in the right MF region. Cross correlation analysis demonstrated that for 88.7% of the bilateral MF spikes (172/194, 88.7%) the left MF spike led the contralateral spikes with relative fixed peak‐to‐peak intervals (18.9 ± 11.1 ms) and high cross correlation values (0.81 ± 0.10). An estimated conduction velocity of 7.2 ± 9.8 m/sec was calculated (assuming no synaptic delay). After a second period of more extended invasive EEG monitoring, a left partial frontal lobectomy was performed and the patient immediately had a few brief seizures before remaining seizure‐free for a follow‐up period of 14 months.

Conclusion

We conclude that the propagation of spikes between bilateral MF regions most likely occurs mainly through myelinated callosal fibres. In addition, this cross correlation method showed that the left MF spikes, most of the time, preceded the right MF spikes suggesting that the epileptogenic zone was localized in the left MF region.
Correlation between child and parental perceptions of health‐related quality of life in epilepsy using the PedsQL.v4.0 measurement model
Authors: Haneef Zulfi , Grant Mitzie L. , Valencia Ignacio , Hobdell Elizabeth F. , Kothare Sanjeev V. , Legido Agustin , Khurana Divya
Published: October 2023

Health‐related quality‐of‐life measures in childhood epilepsy are typically limited to a particular functional domain, specific age group, parent proxy‐report, or child self‐report. Generic health‐related quality‐of‐life instruments in paediatric epilepsy comparing child self‐reports with simultaneous parent proxy‐reports have not been previously investigated. A previously validated generic questionnaire, the Pediatric Quality of Life version 4 (PedsQL.v4.0), was used to prospectively assess parental and child perceptions of health‐related quality of life in 100 children with epilepsy. The correlation between child and parental health‐related quality‐of‐life perceptions across all domains was excellent (p < 0.001) and both were significantly lower than those for healthy controls (p < 0.001). Parents' perceptions of their children's health‐related quality of life were lower than those for other chronic illnesses (p < 0.001), especially for refractory epilepsy. The presence of neurological or psychiatric comorbidities also had an adverse impact on health‐related quality of life. The PedsQL.v4.0 measures health‐related quality of life from both the parent's and child's perspective. Ease of use makes this instrument attractive for routine clinical use.
A Study on How an Aging Population Affects the Effectiveness of Fiscal Policy Using an ARDL Model
Authors:   The Korea International Trade Research Institute, Jang Ji-Young
Published: October 2023

Purpose - This paper examines the impact of an aging population on fiscal policy efficiency. Two significant issues arise from Korea’s aging population: old age poverty and the sustainability of government debts. As Korea’s demographic trajectory is similar to that of Japan, it is vital to study fiscal soundness and efficiency from various points of view.
Design/Methodology/Approach - The Autoregressive Distributed Lags (ARDL) - EC model was adopted. ARDL shows statistically robust results when the data are a mixture of stationary at the level or the first difference. The data was downloaded from 1994 to 2019 of five OECD countries; Canada, Japan, Spain, Sweden, and Korea. The country selection followed the regime classification of OECD (2012) based on the labor market structure and redistribution effect after tax.
Findings - First, the dependency ratio negatively affects the efficiency of fiscal policy. The marginal propensity was suppressed due to the consumption variance in old age cohorts as the dependency ratio increases. Economic agents react to save for future uncertainty when government spending is funded by issuing debt. Second, the long-term elasticities differed among countries, with Korea having the highest at 0.56, followed by Canada at 0.55, Spain at 0.39, and Japan at 0.36.
Research Implications - Efficiency of fiscal policy is dependent upon the reactions of economic agents. The priority of the government should focus on managing the future expectations of economic agents by implementing structural reforms in the labor market and pension system.
Fandom Management Strategies for the K-Content Industry
Authors:   The Korea International Trade Research Institute, Lee Hyun-Eung , Kim Joon-Hwan
Published: October 2023

Purpose - Based on several keywords, this study proposes three specific strategies and action plans to manage the K-content fandom.
Design/Methodology/Approach - With the revitalization of the K-content industry becoming a major strategy for increasing national competitiveness in Korea, this study proposes specific strategies to manage the fandom from three perspectives for the growth and development of the K-content industry. These are not macro strategies, but micro strategies that focus on specific areas.
Findings - First, misinformation should be managed in the process of communication with the fandom. This requires developing the political, social, and cultural sensitivity of artists, sharing visions and values to ensure consistency in the messages delivered, and supporting fandoms to establish a system to respond to misinformation. Second, the mental health of artists should be managed by their agencies. Because the psychological well-being of the artists is a major concern for the fandom now, agencies should provide professional counseling or therapy services while creating an environment that prevents exposure to verbal abuse and invasions of privacy. Third, K-content agencies should manage the leadership brand of their companies. Through the establishment of a leadership brand customized to the fandom, a positive corporate image and rapport with the fandom based on understanding and empathy should be formed. Finally, this study provides suggestions for further research on fandom management.
Research Implications - This study aims to contribute to the sustainable growth of the K-content industry by specifically presenting strategies that entertainment companies can take in the process of fandom management.
The Effect of the ASEAN FTA on Intra-Regional Trade in Lao PDR
Authors:   The Korea International Trade Research Institute, No Joung-Yeo , Phavisone Chanhsuda
Published: October 2023

Purpose - This study aims to estimate the effects of the Association of South-East Asian Nations Free Trade Area (AFTA) on international trade in Lao People’s Democratic Republic (PDR) Design/Methodology/Approach - This study empirically analyzes the effects of AFTA on Lao PDR’s intra-regional trade with ASEAN countries using a gravity model by employing panel data from ten ASEAN countries from 1990 to 2017.
Findings - This paper finds that joining AFTA positively affects aggregate trade volume and exports of Lao PDR. However, joining AFTA does not positively impact Lao PDR’s imports.
Research Implications - With a very limited number of studies on the effect of AFTA on Lao PDR, most previous studies examine the effect on Lao PDR using a subset of ASEAN countries. This paper contributes to the literature by being the first to empirically analyze the effect of AFTA on intra-regional trade in Lao PDR with all ten ASEAN member countries. The findings of the study suggest that further extending FTA networks with other countries will promote Lao PDR’s trade and its access to the international market.
African Trajectories of Pier Luigi Nervi’s Engineering Office
Authors: Boller Giulia
Published: October 2023

Micaela Antonucci and Gabriele Neri's book offers for the first time an overview of the projects that Pier Luigi Nervi's Italian engineering office designed and built in post-colonial African countries between 1964 and 1980. Through the detailed description of some major works, the text shows how the "Nervi System" gradually became a stylistic language, leaving behind the relationship between architectural and structural forms that had characterized Nervi's well-known projects.
Smartphone film, memory’s connective turn and the aesthetics of embodiment in Do You Remember That Year? (2020)
Authors: Cieplak Piotr
Published: October 2023

Do You Remember That Year? (DYRTY?) is a short film about anxiety, privilege, and the difficulty of reconciling the internal and external stimuli that bombard us daily. DYRTY? probes the need to narrativize experiences that are recorded but not necessarily remembered in what Hoskins (2011) calls the memorial ‘connective turn.’ This submission examines the potential aesthetic and narrative responses to the ‘connective turn,’ defined asan ‘ontological shift in what memory is and what it does’ in response to the proliferation of digital technologies (Hoskins and Halstead 2021:675). In particular, it addresses Hoskins’ question about the use of mobile devices to capture images: ‘What is our capacity to actually mobilise the archive of our experiences so that we come to comprehend our past […] in a meaningful and functional way (ibid, p. 678). In discussing the approaches employed in DYRTY?, I propose a meaningful deployment of what surrounds the image; its ecology. In particular, I argue for an engagement with ‘the aesthetics of embodiment’ (Rutherford 2003). This approach allows for the exploration of the openly subjective ‘metonymic slippage between vision, the image, the eye and the ‘I’ of subjectivity’ (Doane 1985:61) and, consequently, the location of this subjectivity within the wider ecology where ‘the perceiver constantly locates him or herself in the environment, that what we perceive is not data about the environment out there, but “the significance of surfaces in relation to our body”’ (Cataldi 1993:112 ). I argue that Smartphone recording and story-telling technology and aesthetics are uniquely placed to explore the complexities of openly subjective representation rooted both in and outside its immediate environment.DYRTY? is currently on the festival circuit. So far it has won the Best International Premiere Video Award at the Avanca Film and Video Festival (Portugal) and the Best Smartphone Film Award at the South Coast Film Festival (U.K.). It also screened as part of the Film Geographies panel at the 2021 Royal Geographical Society conference.
U.S. Families’ Experiences of the COVID-19 Pandemic: Evidence from the Survey of Consumer Finances
Authors: Bricker Jesse , Goodman Sarena , Moore Kevin , Reber Sarah , Volz Alice Henriques , Windle Richard
Published: October 2023

Between 2019 and 2022, the COVID-19 pandemic caused severe disruptions to the U.S. labor market and broader economic activity, leading to unprecedented levels of fiscal support. Nonetheless, over this period, net changes in major economic indicators were consistent with a robust economy, and according to the 2022 Survey of Consumer Finances (SCF), U.S. families experienced broad-based improvements in their finances, particularly with respect to net worth (Aladangady et al., 2023).
Likelihood of whole-grade or subject acceleration for twice-exceptional students
Authors: LeBeau Brandon C , Assouline Susan G , Foley-Nicpon Megan , Lupkowski-Shoplik Ann , Schabilion Katherine
Published: October 2023

Academic acceleration, which enhances challenges for academically gifted students, can be subject-based or whole-grade. Limited research has explored its application in the twice-exceptional population, where students possess notable cognitive strengths and challenges due to psychological diagnoses. Our clinical study investigates the likelihood of subject or whole-grade acceleration, considering IQ, age, and achievement differences across diagnosis types and demographics. Subject-based acceleration is more likely for students with diagnoses of depression or anxiety, gifted program participation, or medium socioeconomic status. Males with specific learning disabilities (SLD) are less likely to be subject-based accelerated. Whole-grade acceleration was likelier for students diagnosed with anxiety. At the same time, those with medium or low socioeconomic status, and ADHD, ASD, or SLD diagnoses, were less likely to be whole-grade accelerated.
Exchange of Alcohol Culture during the Mongol Empire
Authors:   The Korean Association for Mongolian Studies, Kim Kyongna , Jeong Hojun
Published: October 2023

This study examines the exchange and influence of alcohol, often hailed as the greatest gift bestowed upon humanity, as it traversed the Eurasian continent from east to west and vice versa. Rather than being a mere beverage for enjoyment, alcohol should be regarded as a cultural heritage born from the fusion of local products and cultures. This paper gathers historical records on wine to explore how the people of the Mongol Empire enjoyed wine, and investigates the spread and diffusion of fermented beverages like Maotai and the distilled spirits derived from them, shedding light on the North-South cultural exchange of alcohol during the early 13th century in the steppe and the central plains.
In particular, the invention of distillation apparatus and the activities of Islamic merchants contributed to the vast dissemination of distilled spirits throughout the vast regions of Eurasia, giving rise to various types of alcohol such as arrack and soju in the east, and whisky, brandy, vodka, and tequila in the west. This, too, can be seen as a result of extensive cultural exchange between the East and the West. The active exchange of alcohol during the era of the Mongol Empire was made possible by the empire's expansion of territories in all directions, establishing an empire that not only exerted political and military control over neighboring countries but also provided opportunities for subordinate ruling classes to participate in advanced civilization. Additionally, the empire secured hubs for exchanging goods between border regions and central cities, leading to the flourishing of economic exchanges, both public and private, between regions.
This paper examines how the spread of alcohol in East Asia occurred in both the northern and southern directions, centered around the Mongol Empire, during different periods before and after the empire's existence. Contrary to our general assumption that alcohol spread unilaterally from China to Southeast Asian countries, it was confirmed that various types of fermented beverages produced in the region were introduced to China as trade developed. Likewise, distilled spirits were introduced to China through maritime and overland trade routes, and with the construction of a universal empire, the spread of these alcoholic beverages to other regions became more active, contributing to their popularization. This, too, can be seen as a cultural exchange phenomenon brought about by Pax Mongolica.
Comprehensive exosomal microRNA profile and construction of competing endogenous RNA network in autism spectrum disorder: A pilot study
Authors: Zhao Sha , Zhong Yan , Shen Fang , Cheng Xinning , Qing Xiaojuan , Liu Jiamin
Published: October 2023

Exosomes have been demonstrated to exert momentous roles in autism spectrum disorder (ASD). However, few studies have reported a correlation between exosomal microRNAs (miRNAs) and ASD. To date, our understanding of crucial competing endogenous RNA (ceRNA) networks in ASD remains limited. Herein, the exosomal miRNA profile in the peripheral blood of children with ASD and healthy controls was investigated and the level of immune cell infiltration in ASD was evaluated to determine the distribution of immune cell subtypes. Exosomes were isolated from the peripheral blood of ten children with ASD and ten healthy controls, and further identified using transmission electron microscopy and western blot analysis. RNA sequencing was conducted to investigate exosomal miRNA profiles in patients with ASD. The mRNA and circular RNA (circRNA) expression profiles were acquired from the Gene Expression Omnibus (GEO) database. Differentially expressed mRNAs (DEmRNAs), miRNAs (DEmiRNAs), and circRNAs (DEcircRNAs) were identified and ceRNA regulatory networks were constructed. Furthermore, the immune cell infiltration levels in patients with ASD were evaluated. Exosomes were spherical, approximately 100 nm in size, and were confirmed via western blot analysis using exosome-associated markers CD9, CD63, and CD81. Thirty-five DEmRNAs, 63 DEmiRNAs, and 494 DEcircRNAs were identified in patients with ASD. CeRNA regulatory networks, including 6 DEmRNAs, 14 DEmiRNAs, and 86 DEcircRNAs, were established. Correlation analysis indicated that leucine-rich glioma inactivated protein 1 (LGI1) expression was significantly positively correlated with the content of CD8+ T cells. Our findings may be conducive to offering novel insights into this disease and providing further evidence of transcriptomic abnormalities in ASD.
Personality, social distance and conflicts: Personality functioning, empathy and socioeconomic factors predicting social distancing and conflicts with minorities
Authors: Preiss Marek , Heissler Radek , Doubková Nikola , Sanders Edel , Jonáš Juraj
Published: October 2023

Objective. Although previous studies pointed to various aspects of social distance and conflicts with representatives of otherness, associations with objectively measured aspects of personality in the form of a semi-structure interview combined with observation are less common. Based on previous studies, this study focused on the relationship between social distance and conflicts with representatives of otherness. It was hypothesized that the lower the personality functioning, the higher will be social distance and more conflicts with representatives of otherness will be reported. We assumed that impaired empathy would be associated with higher social distance in comparison with other variables of personality functioning derived from Alternative Model for Personality Disorders (AMPD) – identity, self-direction and intimacy. Sample and methods. Participants (N = 204) were recruited from several contrast groups including clinical and measures focused on conflicts, personality functioning (STiP-5.1), social distance (Bogardus Social Distance Scale). Additionally, several related methods were used. Results. Increased impairments in identity, self-direction, empathy, and intimacy were associated with a higher degree of subjective importance of conflicts with representatives of otherness. Greater social distance was associated with impairments in self-direction and empathy. However, social distance was found independent of subjectively experienced conflicts. Multivariate linear regressions showed that social distance was predicted by education, racism, and personality functioning (STiP-5.1 – Self-direction), BR and SR scores, explaining 58 per cent of the variance. Conclusions. The subjective importance of conflicts and social distance to representatives of otherness is associated with AMPD.
Proteolytic Peptide Desalting with C18 Hydrophilic–Lipophilic Balance (HLB) Cartridges v1
Authors: not provided JBons , P Rose J , A Watson M , Schilling B
Published: October 2023

Desalting of proteolytic peptide elution using C18 Hydrophilic–Lipophilic Balance (HLB) Cartridges in preparation for downstream proteomic profiling.
Illumina double-stranded DNA dual indexing for ancient DNA v2
Authors: Stahl Raphaela
Published: October 2023

This protocol converts partially completed double-stranded DNA libraries e.g. from: Non-UDG treated double-stranded ancient DNA library preparation for Illumina sequencing (dx.doi.org/10.17504/protocols.io.bakricv6) into dual-indexed Illumina libraries ready for sequencing on an Illumina platform. Other variants of the above protocol can also be used. This protocol includes steps for indexing PCR, clean-up, and post-indexing qPCR. This protocol is modified after Kircher, M., Sawyer, S. & Meyer, M., 2012. Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform. Nucleic acids research, 40(1), p.e3. http://dx.doi.org/10.1093/nar/gkr771.
Cell Viability Assay (MTT Assay) Protocol v1
Authors: not provided aasirvatham
Published: October 2023

The purpose of this experiment is to investigate the effects of forskolin-mediated cAMP activation on the viability of LPS-treated Schwann cells. The immortalized rat RT4-D6P2T (ATCC #CRL-2768) and S16 (ATCC #CRL-2941) cell lines were cultured and received one of the following treatments: 0.1, 1, or 10 μg/mL of LPS, in N2 media (control) or N2 media supplemented with 2 µM of forskolin, for 1, 3, 12, or 24 hours, and the CyQUANT MTT Cell Viability Assay Kit (Thermo Fisher) was used to perform the viability assay.
Protocol for Facially Guided Digital Diagnosis in Orthodontics v2
Authors: HG Kelley Rupert , Ferrando Cascales Álvaro , Ferrando Cascales Raúl
Published: October 2023

As the digital age of dentistry continues to flourish, it has never been more important to have protocols to guide dentists through the planning and performance of treatments using the latest technology and software. This is especially true in the field of orthodontics, where the use of technology has revolutionised treatment outcomes. During the first stages of this protocol, extensive records are collected which are then used throughout the treatment. After that, a shift occurs from two dimensions to three dimensions, and movement of the maxillary teeth begins. Then, the mandibular teeth are moved, and the case is completed. The final step is to check the results and ensure that our outcome matches what was planned before the commencement of treatment. This protocol aims to guide orthodontists in the treatment of their patients no matter the type of treatment that is planned, whether orthodontic, restorative or surgical. At any stage of the treatment, the orthodontist can refer back to the protocol to stay on the path towards a successful outcome for the patient.
The effect of science technology engineering mathematics (STEM) learning on respiratory system topic on students’ numerical ability
Authors: Rahmawati Ane Laksana Lintang , Nuraeni Eni , Wulan Ana Ratna
Published: October 2023

The purpose of this study was to analyze the effect of STEM learning on students' numeracy skills. STEM learning was carried out through the activity of making a UV sterilizer prototype in one class with six groups in it. Data collection was carried out before, during, and after learning. The instruments used were written tests of numeracy skills, observation sheets, and students’ questionnaires response. The effect of learning was tested through paired sample t-test and N-gain. Data collection was carried out in one class of XI IPA at Senior High School in Bandung with 21 participating students. The results showed that STEM learning had an effect on numeracy skills, with significant results (t (21) = -5.87, p = 0.00), and moderate increase (N-gain = 0.46).
Florisztikai adatok Észak-Magyarországról III. Zempléni-hegység
Authors: Vojtkó András , Farkas Tünde
Published: October 2023

We report new floristic data collected from the Zemplén Mountains between 2004–2022. Altogether, 1215 occurrences of 133 species were recorded from 33 Central European Flora Mapping quadrats. We present occurrences of so far not reported or rare species, e.g., Carex appropinquata, C. cespitosa, C. disticha, Centaurea stenolepis, Scabiosa columbaria, Tephroseris aurantiaca. We put special emphasis on occurrence data of geobotanical importance, such as Anthriscus nitidus, Echium maculatum, Lunaria rediviva, Nepeta pannonica, Oreopteris limbosperma, Petasites albus, Primula elatior, Thlaspi jankae, Veronica montana, as well as newly rediscovered species based on archive data: Cirsium rivulare, Parnassia palustris. We mention common species, which are lacking data from the area, e.g., Adoxa moschatellina, Allium flavum, Cardamine amara, Dipsacus fullonum, Galanthus nivalis. Moreover, we report numerous new occurrences of taxa typical to the Zemplén Mts.: Aruncus dioicus, Huperzia selago, Lycopodium annotinum, Securigera elegans etc. We complete the enumeration with additional data from the literature and herbaria.
Combined photodynamic and radiodynamic therapy with a chlorine photosensitizer under fractionated radiation exposure to transplanted tumors in an in vivo experiment
Authors: Tzerkovsky D. A. , Mazurenko A. N. , Kozlovsky D. I. , Adamenko N. D. , Borichevsky F. F.
Published: October 2023

Introduction. The current direction of scientific research in experimental and clinical oncology is radiodynamic therapy (RDT), a treatment method based on the activation of photosensitizers (PS) by ionizing radiation. As the results of in vitro / in vivo studies show, a number of photosensitizing agents have radiomodifying properties, and the method itself is characterized by high antitumor efficacy.

Aim. To study the possibility of increasing the effectiveness of photodynamic therapy (PDT) through its combined use with RDT in an in vivo experiment.

Materials and methods. The work was performed on 26 white non-linear rats weighing 180 ± 50 g. Pliss lymphosarcoma was used as a tumor model, which was transplanted subcutaneously. The chlorine-based PS (Belmedpreparaty, Republic of Belarus) was administered intravenously at a dose of 2.5 mg / kg of body weight. The RDT session was performed by the contact method (CRT) after 2.5–3, 24 and 48 hours after the end of PS administration on the microSelectron-HDR V3 Digital device (Elekta, Sweden) using γ-radiation (192Ir) in a single focal dose (SFD) of 2 Gy until the total focal dose of 6 Gy is reached. A PDT session was performed once immediately after the first exposure to ionizing radiation using a PDT diode laser (Imaf Axicon, Republic of Belarus, λ = 660 ± 5 nm) at an exposure dose of 100 J / cm² with a power density of 0.2 w / cm² and a power of 0.353 w. All rats were divided into 4 groups of 6–7 animals each: intact control, PS + PDT, PS + CRT, PS + CRT + PDT. The criteria for evaluating antitumor efficacy were: the average volume of tumors (Vav), the coefficient of absolute growth of tumors (K), the coefficient of tumor growth inhibition (TGI), the frequency of complete tumor regressions (CR), the proportion of cured rats, an increase in the average duration of dead rats. Differences were considered statistically significant at p <0.05.

Results. On the 18th day of the experiment, Vav in groups was 65.98 ± 0.81 cm³; 24.02 ± 4.01 cm³ (р <0.00001); 17.11 ± 4.13 cm³ (р <0.00001); 4.42 ± 1.65 cm³ (р <0.00001), respectively. Coefficients K – 5497.33 OE; 1714.71 OE; 1424.83 OE; 367.33 OE. TGI coefficients – 63.60 % (PS + PDT); 74.07 % (PS + CRT); 93.30 % (PS + CRT + PDT). An in crease in the average duration of dead rats indicator – 25.31 % (PS + PDT); 55.06 % (PS + CRT); 158.22 % (PS + CRT + PDT). On the 60th and 90th days of the experiment, the frequency of CR and the proportion of cured rats were the same and amounted to 0; 16.7; 14.3 and 42.9 %, respectively.

Conclusion. The results obtained indicate that the chlorine PS has, in addition to photosensitizing properties, also radiomodifying properties, and the developed method of combined therapy is characterized by high antitumor efficacy.
FORENSIC PRINCIPLES OF INTERROGATION TACTICS OF A VICTIM OF DOMESTIC VIOLENCE
Authors:   Scientific research institute Ministry of Internal Affairs of Ukraine, Kyiv, Ukraine, DROZD V.G.
Published: October 2023

The article analyzes the forensic principles of interrogation tactics for a victim of domestic violence and provides suggestions for optimizing the relevant process in the form of recommendations. The importance of carrying out the highest quality investigative (inquiry) actions in the pre-trial investigation of criminal offenses of violent content in general, as well as domestic violence, as one of the most dangerous types of illegal behavior in particular, is proved. In addition, attention is drawn to the fact that interrogation, among other investigative (inquiry) actions, is the most functionally applicable and universal investigative (inquiry) action, which allows to establish and detail a wide range of information about the criminal offense and the relevant subject of its commission. The purpose of the article is to analyze the principles of forensic tactics existing in science for interrogating a victim of domestic violence. This, in turn, necessitates the solution of such research problems as: 1. Delineation of the terminological component of the subject of a scientific article; 2. Detailing existing ideas about the tactics of interrogation of victims of domestic violence with the identification of the most outdated of them; 3. Identification of current trends in the principles of forensic tactics of interrogation of a victim of domestic violence and making proposals for discussion on ways to optimize the functioning of the relevant institution. The prospect of further scientific development of the relevant topics lies in the need to study the forensic tactics of interrogation of other persons participating in criminal proceedings for domestic violence.
Acute paraproctitis and anal fistula in children: A review
Authors: Zyuzko Daria D. , Shcherbakova Olga V.
Published: October 2023

Acute paraproctitis and pararectal fistulas are common diseases in infants and adolescents. To date, discussions are ongoing about whether to use conservative or surgical treatment options, their implementation, and the use of antibiotics during the perioperative period. The study is based on a literature review of treating children with this pathology. The databases in Russian eLibrary.ru and English Medline, Web of Science, and PubMed were searched for literature sources. The following keywords were entered into the search: acute paraproctitis, pararectal fistulas, fistulotomy, and fistulectomy. There were 155 papers discovered, 51 of which were congruent with the purpose of our study and were evaluated. According to the data presented in the literature review, pararectal fistula is the outcome of acute paraproctitis in 20%85% of cases. The cause of acute paraproctitis and pararectal fistulas in children is unknown. Imaging methods that allow you to identify all the hidden passages and characterize the relationship between the fistula and the anal sphincter play an important role in diagnosing pararectal fistulas. Cellular technologies are being used as a conservative treatment with established approaches. Incision and drainage are the preferred surgical procedures in treating acute paraproctitis, and fistulotomy is used in pararectal fistulas. Stem cell therapy is described as a promising treatment. Relapses of paraproctitis and/or the establishment of pararectal fistulas occur at a rate ranging from 0% to 85%. Such a large range may be related to the nature of the treatment and how fistulas are classified as relapses or complications. The recurrence of abscesses and anal fistulas is closely related to the type of surgical intervention. If the channel of the anal fistula is not identified and not dissected, the risk of recurrence is relatively high. Based on the findings of the data analysis, it is possible to infer that there is currently no single procedure for treating children with acute paraproctitis and pararectal fistulas. This explains the importance of performing randomized prospective studies to determine the best treatment strategies for children with this pathology.
Platelet-rich plasma in surgical practice: a review
Authors: Minaev Sergey V. , Timofeev Sergey I. , Grigorova Alina N. , Vladimirova Oksana V. , Bolotov Yuriy  N. , Yachnaya Oksana I. , Stroganov Mikhail G.
Published: October 2023

The use of platelet-rich plasma (PRP) in clinical settings is a current issue in various fields of medicine. There is no unified and structured approach to PRP preparation and application stages. This review examines the literature data on the use of PRP in surgical practice. Data were analyzed using scientific sources from scientific citation platforms, such as RSCI, PubMed, Scopus, and Web of Science. This review describes the most commonly used methods and techniques for preparing PRP in laboratory and experimental conditions. Using data from clinical and experimental studies, the possibility and effectiveness of using PRP in routine and experimental surgical practice were analyzed. PRP has relatively wide range of applications in various areas of clinical medicine; however, its use in pediatric surgical practice requires further study, including the development of indications and contraindications.
Сomplications and functional outcomes after restorative proctocolectomy with ileal pouch–anal anastomosis in children: A single-center experience
Authors: Khabibullina Linara R. , Razumovsky Alexander Yu. , Shсherbakova Olga V.
Published: October 2023

BACKGROUND: Restorative proctocolectomy with ileal pouchanal anastomosis is a prominent treatment for adult patients with ulcerative colitis and familial adenomatous polyposis, with satisfactory functional outcomes. In literature, that technique in pediatric practice is described; however, in the domestic literature, there is no mention of ileal pouchanal anastomosis in children.
AIM: This study aimed to examine the outcomes of ileal pouchanal anastomosis in pediatric patients.
MATERIALS AND METHODS: The study comprised 33 patients with an ileal pouchanal anastomosis between January 2019 and June 2023. At the time of the ileal pouchanal anastomosis, the average age was 13 (5) yr. Patients were followed for an average of 17 (14) months.
RESULTS: Patients with ulcerative colitis underwent three-stage surgical interventions more often than patients with another diagnosis (90% vs. 4%, p 0.0001), and the mean duration of surgery in ulcerative colitis patients was shorter than in patients with polyposis syndromes or total agangliosis: 173 (57) min versus 280 (73) min. Late complications were reported in five (15%) patients undergoing ileal pouchanal anastomosis. After the ileal pouchanal anastomosis, analysis of patient questionnaires revealed that children had satisfactory functional results.
CONCLUSIONS: Several encouraging studies have confirmed good functional outcomes after ileal pouchanal anastomosis. Our findings suggest that ileal pouchanal anastomosis in children is associated with favorable results.
To the Centenary of Yuri F. Isakov
Authors: Gorbachev Oleg S.
Published: October 2023

The paper describes the professional activities and merits of the pediatric surgeon Yuri F. Isakov.