bluuebunny/crossref_metadata_2025 huggingface dataset:
The Elephant in the Room: Youth, Cognition, and Student Groups in Mass Social Movements
Authors: Johnston Hank
Published: August 2019

Student and youth groups are often vanguard actors in turbulent times. This article proposes that when they are part of broader social movements, they can introduce strong age-cohort influences in a movement’s development. These influences derive from the balance between youths and adults in a movement and their interrelationships, especially over the long term when demands remain unanswered by the state. Other influences include resource availability, which tends to cluster with older generations, tactical specialization according to age cohorts, and the tendency of groups with younger members to be willing to take greater risks, be more passionate in their demands, and more militant in their tactics. In this report, we identified several empirically recognized cognitive dimensions relevant to youthful participation: (1) identity search, (2) risk taking, (3) emotionality, and (4) cognitive triggering. These cognitive factors of late adolescence and early adulthood can energize a movement when young cohorts participate but also run the risk of alienating older members and public opinion. We discussed how mass movements for political and/or cultural change are frequently intergenerational and how intergenerational relations can mitigate the inward-turning and militant tendencies of young adults. In broad movements for social change, these relations can create a division of labor in which students are the vanguard actors and the older members mobilize the social and material resources available to them. Under other conditions, youth and student groups wield a two-edged sword with the capability of energizing a movement or alienating older cohorts of militants and public opinion.
The Reliability of Using a Laser Device to Assess Deceleration Ability
Authors: Ashton Jonty , Jones Paul A.
Published: August 2019

An important component of change of direction speed is the ability to decelerate. Objective methods to examine this quality have been rarely reported in the literature. The aim of this study was to investigate the within- and between-session reliability (intraclass correlation coefficients (ICC), coefficient of variation (CV), standard error of measurement (SEM) and smallest detectable difference (SDD)) of using a laser Doppler device (LAVEG—LAser VElocity Guard) to quantify deceleration ability in 20 amateur rugby union players. Each player performed one familiarisation and two experimental sessions (seven days apart) consisting of three maximal 15 m sprints from a standing start, with an immediate deceleration to a complete stop upon hearing an audible cue at the 15 m mark. Deceleration was evaluated by determining the distance required to decelerate to 75%, 50%, 25% and 0% (‘stopping distance’) of the velocity achieved at 15 m of the maximal sprint. Within-session relative reliability was moderate to good (ICC = 0.64–0.83) with borderline acceptable variation (CVs = 10.51%–16.71%) across all variables. Between-session reliability reported good to excellent relative reliability (ICC = 0.79–0.93) with acceptable absolute reliability, particularly for stopping distance (SEM: 6.54%; SDD: 9.11%). The assessment shows promise as a method to quantify deceleration ability in athletes.
Sustainable Management of Coastal Wetlands in Taiwan: A Review for Invasion, Conservation, and Removal of Mangroves
Authors: Chen Yu-Chi , Shih Chun-Han
Published: August 2019

Mangrove management has been a sustainable concern in coastal wetlands for decades, especially for original near-shore wetlands and environments without mangrove forests. Although studies outlining environmental, social, and economic benefits of mangrove forests have been increasing, few studies have examined sustainability and policies for reducing or removing mangroves. This study explores the current implemented strategies pertaining to the invasion, conservation, and removal of mangroves for wetland sustainability. A total of 19 mangrove sites were sorted out to develop the main patterns and factors for the destruction or protection in estuaries on the western coast of Taiwan. For traditional wetland management, when faced with development pressure, having protected areas under certain laws is a good direction to go for mangrove sustainability. Furthermore, due to the invasion of mangroves in the mudflats, the Siangshan Wetland indicated mangrove removal can be a positive conservation case as an appropriate habitat rehabilitation strategy for benthic organisms. Under special conditions, mangrove removal provides useful insights into the sustainability of wetlands. These insights contribute to facilitating the worldwide move towards sustainable management on mangrove wetlands. The study also presents the following strategies to further reduce or remove mangroves in the coastal wetlands that contain no mangrove forests: (1) Conducting studies to evaluate the effectiveness of mangrove removal; (2) implementing policies to ensure positive influences on coastal wetlands, and (3) providing mangrove conservation education for sustainable development.
Modelling Organisational Factors Influencing Sustainable Development Implementation Performance in Higher Education Institutions: An Interpretative Structural Modelling (ISM) Approach
Authors: Awuzie Bankole Osita , Abuzeinab Amal
Published: August 2019

Globally, higher education institutions (HEIs) have continued to record varied sustainable development (SD) implementation performances. This variance has been attributed to the presence of certain organisational factors. Whereas previous studies have successfully identified the factors influencing SD implementation performance in HEIs, few studies have attempted to explore the relationship between these factors and the influence of such a relationship on the management of SD implementation in HEIs. This is the objective of this study. Understandably, knowledge of such relationships will facilitate the development of appropriate frameworks for managing SD implementation in HEIs. Relying on a case study of a South African University of Technology (SAUoT), this study elicits data through a focus group discussion session. An interpretative structural modelling (ISM) focus group protocol indicating extant pair-wise relationships between identified organisational factor categories was extensively discussed. The emergent data was recorded, transcribed verbatim and subsequently analysed. The findings suggest that communication was critical to the prevalence of other factors, hence indicating its centrality to the effective management of SD implementation in HEIs. These findings will guide implementing agents in HEIs towards developing appropriate mechanisms for communicating SD implementation strategies.
Spillover Effects of Ports and Logistics Development on Economic Power: Evidence from the Chinese BTH Regions
Authors: Han Feiyan , Wang Daming , Li Bo
Published: August 2019

Ports and logistics development strongly affect the development of regional economies. This paper chooses the Beijing–Tianjin–Hebei (BTH) regions as the study area, and aims to reveal the spillover effects of ports and the contribution of logistics development to the growth of regional economics based on the partial least squares (PLS) and ordinary least squares (OLS). We apply the panel data analysis for the period of 1996 to 2015 through an expanded Cobb–Douglas production function. Four models are established to analyze the influences of the different indicators on the economic development. The results show that the Tianjin Port has a considerably stronger influence on the BTH regions than the Hebei ports, and its spillover effects on the sub-regions are notably stronger. Furthermore, several indicators have a negative effect on one sub-region, while they have a positive effect on the other sub-regions. Finally, we make practical suggestions that will stimulate and coordinate regional economic development.
A Bidirectional Power Charging Control Strategy for Plug-in Hybrid Electric Vehicles
Authors: Mohammadi Fazel , Nazri Gholam-Abbas , Saif Mehrdad
Published: August 2019

Plug-in Hybrid Electric Vehicles (PHEVs) have the potential of providing frequency regulation due to the adjustment of power charging. Based on the stochastic nature of the daily mileage and the arrival and departure time of Electric Vehicles (EVs), a precise bidirectional charging control strategy of plug-in hybrid electric vehicles by considering the State of Charge (SoC) of the batteries and simultaneous voltage and frequency regulation is presented in this paper. The proposed strategy can control the batteries charge which are connected to the grid, and simultaneously regulate the voltage and frequency of the power grid during the charging time based on the available power when different events occur over a 24-h period. The simulation results prove the validity of the proposed control strategy in coordinating plug-in hybrid electric vehicles aggregations and its significant contribution to the peak reduction, as well as power quality improvement. The case study in this paper consists of detailed models of Distributed Energy Resources (DERs), diesel generator and wind farm, a generic aggregation of EVs with various charging profiles, and different loads. The test system is simulated and analyzed in MATLAB/SIMULINK software.
The Eigenproblem Translated for Alignment of Molecules
Authors: Jäntschi Lorentz
Published: August 2019

Molecular conformation as a subproblem of the geometrical shaping of the molecules is essential for the expression of biological activity. It is well known that from the series of all possible sugars, those that are most naturally occurring and usable by living organisms as a source of energy—because they can be phosphorylated by hexokinase, the first enzyme in the glycolysis pathway—are D-sugars (from the Latin dextro). Furthermore, the most naturally occurring amino acids in living cells are L-sugars (from the Latin laevo). However, a problem arises in dealing with the comparison of their conformers. One alternative way to compare sugars is via their molecular alignment. Here, a solution to the eigenproblem of molecular alignment is communicated. The Cartesian system is rotated, and eventually translated and reflected until the molecule arrives in a position characterized by the highest absolute values of the eigenvalues observed on the Cartesian coordinates. The rotation alone can provide eight alternate positions relative to the reflexes of each coordinate.
A New on-Demand Recharging Strategy Based on Cycle-Limitation in a WRSN
Authors: Wang Yuhou , Dong Ying , Li Shiyuan , Huang Ruoyu , Shang Yuhao
Published: August 2019

Recently, Wireless Rechargeable Sensor Networks (WRSNs) have been attracting increasing attention and seen rapid development. However, in previous studies, pioneering work on charging issues and data gathering strategies are always discussed separately. In this paper, we aimed to develop a strategy which can guarantee a short data acquisition cycle and high charging efficiency. We used a new Combined Recharging and Collecting Data Model (CRCM) to set-up a WRSN. In this network, mobile chargers were used to separately collected data and charge sensor nodes. A K-means algorithm was used to group sensor nodes into different clusters, from which mobile chargers collected data from sensor nodes in the center of these clusters. The Nearest-Job-Next with Preemption (NJNP) algorithm was used to determine the charging route. The data acquisition cycle was first discussed in this model in order to ensure all data from the sensor nodes could be gathered within a certain time period. Additionally, the Periodically Restricted Dynamic Mobile Chargers (PRDMCs) algorithm was proposed to determine the number of mobile chargers. Lastly, we used the normal CRCM for comparison with our new CRCM, and the results showed that the new CRCM can effectively safeguard the data acquisition cycle without requiring the addition of more mobile chargers.
Production of Recombinant EAV with Tagged Structural Protein Gp3 to Study Artervirus Minor Protein Localization in Infected Cells
Authors: Matczuk Anna Karolina , Chodaczek Grzegorz , Ugorski Maciej
Published: August 2019

Equine arteritis virus (EAV) is a prototype member of the Arterivirus family, comprising important pathogens of domestic animals. Minor glycoproteins of Arteriviruses are responsible for virus entry and cellular tropism. The experimental methods for studying minor Arterivirus proteins are limited because of the lack of antibodies and nested open reading frames (ORFs). In this study, we generated recombinant EAV with separated ORFs 3 and 4, and Gp3 carrying HA-tag (Gp3-HA). The recombinant viruses were stable on passaging and replicated in titers similar to the wild-type EAV. Gp3-HA was incorporated into the virion particles as monomers and as a Gp2/Gp3-HA/Gp4 trimer. Gp3-HA localized in ER and, to a lesser extent, in the Golgi, it also co-localized with the E protein but not with the N protein. The co-localization of Gp3-HA and the E protein with ERGIC was reduced. Moreover, EAV with Gp3-HA could become a valuable research tool for identifying host cell factors during infection and the role of Gp3 in virus attachment and entry.
APPLICATION OF PLASMA SILICATION METHOD TO WEAR RESISTANCE OF THE PART
Authors: Романцов Р. , Romancov R. , Серых И. , Serykh I. , Чернышева Е. , Chernysheva E.
Published: August 2019

Modern technologies are the most important component for any state. Today, advanced technologies allow to create any mechanisms at the level of atoms and molecules. For the production of machines, aggregates and their individual components, new nanomaterials and nanotechnologies are used, which reduce friction repeatedly and with high efficiency, protect parts from damage, save energy and increase the reliability of machine parts as a whole. Virtually in any mechanism, some parts focus on the main load. In this study, such a detail is the steel clamping collet 65G. A method of plasma siliconizing is proposed for hardening its inner surface. The raise of this characteristics will allow to increase its service life, and therefore will ensure more reliable operation of both a separate mechanism and production as a whole. This allows the enterprise to become cost-effective and competitive. In this paper, the magnitude of the effect of the silicon atoms introduction into the surface layer of a part on wear resistance and durability is investigated. Research and subsequent processing of the results using Statistica software for statistical analysis shows an increase in the strength characteristics by 2.6 times.
MEMPROMOSIKAN PENDEKATAN FENOMENOLOGIS DALAM PENDIDIKAN AGAMA KATOLIK
Authors: Dewantara Agustinus Wisnu
Published: August 2019

Pendidikan Agama Katolik termasuk dalam kategori pendidikan humaniora. Dengan demikian, segala macam pendekatan untuk pengembangan Pendidikan Agama Katolik harus berbasis humaniora juga. Hal ini penting disadari karena dalam dunia pendidikan dewasa ini, pengaruh pendekatan positivistik sangat kuat dan dominan. Artikel ini ingin mempromosikan pendekatan fenomenologis sebagai pendekatan yang relevan dalam penelitian humaniora.
KELUARGA KRISTIANI: LAHAN DAN SUBYEK PENDIDIKAN DASAR TENAGA MISIONER GEREJA
Authors: Ardijanto Don Bosco Karnan
Published: August 2019

Keluarga Kristiani adalah Gereja-Rumah Tangga yang dipanggil untuk ambil bagian dalam karya perutusan Gereja di tengah dunia. Di dalam keluarga terdapat berbagai bentuk pendidikan dasar sekaligus menghadirkan seluruh dimensi penting dalam kehidupan Gereja Selain itu, keluarga Kristiani juga berada pada posisi sangat strategis untuk melaksanakan perutusan Gereja di dunia. Untuk menunjang dan mendorong keberhasilan tugas perutusan Gereja di dunia, maka Gereja perlu menyiapkan para tenaga misionemya sejak dini mulai dari keluarga-keluarga Kristiani. Dengan demikian, keluarga dapat menjadi lahan sekaligus subyek bagi pendidikan dasar para tenaga missioner Gereja.
PEMBELAJARAN DALAM KONTEKS (Sebuah Alternatif Strategi Pembelajaran)
Authors: Supriyadi Agustinus
Published: August 2019

Pembelajaran yang hanya menekankan transfer ilmu dan kurang memperhatikan konteks murid beserta dinamikanya dapat menyebabkan terjadinya jurang antara murid dengan ilmu yang dipelajarinya, dan tidak jarang proses pembelajaran akan mengalami kegagalan. Pada hakikatnya, pembelajaran, pembelajaran  adalah sebuah aktivitas murid.  Subyek pembelajaran adalah murid, dan fungsi guru lebih bertindak sebagai fasilitator atau dinamisator. Untuk mendukung proses pembelajaran dalam konteks, guru perlu melihat, mengamati, menganalisa keadaan murid dengan berbagai dinamikanya. Setelah itu semua dilakukan, kemudian guru merencanakan dan melaksanakan program serta membuat evaluasi berdasarkan situasi nyata berikutnya.
MEMPROMOSIKAN AMSAL DALAM KATEKESE KELUARGA
Authors: Dewantara Agustinus Wisnu
Published: August 2019

The Book of Proverbs is a book in both the Tanakh (Judaism), and the Old Testament (Christianity). The book contains some of the most important teaching and instructions in each of their respective Religions. Most scholars believe that Solomon was the writer of at least part of the book Other authors are mentioned as well, but these references are missing in the Greek Septuagint. The Septuagint sees King Solomon as the author of the whole Book of Proverbs This paper will punctuate the option for Christian family to apply Proverbs in family catechesis. Christian family must be helped in according to preach the value of faith. Teaching with Proverbs that influenced by any parents may be the effective evangelization.
PERAYAAN EKARISTI HARI MINGGU DI PAROKI DAN PERKEMBANGAN HIDUP ROHANI KAUM REMAJA: SEBUAH PELUANG
Authors: Ardijanto Don Bosco Karnan
Published: August 2019

Perayaan Ekaristi hari Minggu di paroki sering dipandang sebagai kegiatan yang bersifat rutinitas belaka. Maka Perayaan Ekaristi masih kui'ang mendapatkan perhatianyang seharusnya. Namun fakta menunjukkan bahwa umat masih tetap datang dan berkumpul menghadiri Perayaan Ekaristi hari Minggu. Ini membuktikan bahwa Perayaan Ekaristi hari Minggu masih mendapat tempat yang istimewa di hati umat beriman, termasuk remaja. Untuk itu para petugas pastoral, khususnya para imam, hendaknya memanfaatkan dengan baik berbagai peluang perayaan Ekaristi hari Minggu untuk membantu mengembangkan hidup rohani umat maupun hidup rohani remaja. Melakukan persiapan yang serius, mengembangkan kreatifitas, serta memanfaatkan berbagai kemungkinan penyesuaian yang dapat dilakukan dalam perayaan Ekaristi membantu terwujudnya pengembangan hidup rohani umat, terutamahidup rohani remaja.
KAUM MUDA KATOLIK, EVANGELISASI DAN KITAB SUCI
Authors: Supriyadi Agustinus
Published: August 2019

Tugas mewartakan Injil Kerajaan Allah merupakan tugas semua anggota Gereja, termasuk di dalamnya adalah Kaum Muda Katolik. Subyek perutusan adalah Gereja, yaitu umat beriman itu sendiri. Iman yang diajarkan oleh Gereja dihidupi oleh Gereja itu sendiri. Kitab Suci dan kegiatan mewartakan lnjil Kerajaan Allah sangat erat berkaitan, karena isi pewartaan bersumber terutama dari Kitab Suci dalam kesatuan dengan Tradisi. Kitab Suci menjadi pendamping utama bagi kaum muda dalam rangka ikut serta melaksanakan tugas perutusan mewartakan Injil Kerajaan Allah.
Inaugural Issue Editorial Note
Authors: Alhosin Mahmoud
Published: August 2019

Welcome to the Inaugural Issue of European Journal of Cell Science, launched in June 2019!
A qualitative analysis of women who have undergone a multi-stage psychotherapy and hypnotherapy intervention to manage psychological stress while undergoing in-vitro fertilisation: What were their experiences and outcomes?
Authors: Patching Alan Francis
Published: August 2019

The literature is rich with studies addressing stress effects on In Vitro Fertilisation (IVF) outcomes. Debate continues regarding whether there is a cause-and-effect relationship, or merely a correlation, between stress and IVF failure. While several studies have addressed coping mechanisms used by couples undergoing IVF, and the effects of coping mechanisms used at three points within an IVF cycle, the author found no study that presented a programme for women to deal with stress before, during and after IVF cycles. Based on evidence from practice, the author devised a five-phased psychotherapy and hypnotherapy protocol (“IVF-Assist”). This qualitative study provides insights from the narratives of eight ‘difficult case’ women who underwent that programme, including one who found she would never be able to carry to term. The narratives of both the seven participants who fell pregnant and the one who was unable to carry to term inform future psychotherapy interventions to assist women better address stress effects that could affect IVF outcomes.
Hubungan Konsumsi Purin Tinggi Dengan Hiperurisemia: Suatu Penelitian Potong Lintang Pada Penduduk Suku Bali di Kota Denpasar
Authors: Indrawan IGNM Budiana , Kambayana Gede , Putra Tjokorda Raka
Published: August 2019

Latar Belakang: Hiperusemia adalah istilah yang menggambarkan kadar asam urat darah di atas normal. Konsumsi purin tinggi merupakan salah satu faktor yang erat kaitannya dengan hiperurisemia.

Tujuan: Penelitian ini bertujuan untuk mengetahui adanya hubungan konsumsi purin tinggi dengan hiperurisemia pada penduduk suku Bali di kota Denpasar.

Metode: Penelitian ini adalah studi potong lintang analitik yang dilakukan pada bulan Juli sampai dengan September 2004. Populasi pada penelitian ini adalah penduduk suku Bali yang bertempat tinggal di Kota Denpasar. Sampel ditentukan dengan cara stratified random sampling. Penilaian konsumsi purin dilakukan dengan semi quantitative food frequency questionnaire. Analisis dilakukan dengan tabulasi silang dan regresi logistik.

Hasil: Penelitian ini melibatkan 302 orang sampel yang memenuhi kriteria inklusi dengan rata-rata umur 43,35 ± 16,72 tahun yang terdiri dari 137 (45,4%) laki-laki dan 165 (54,6%) perempuan. Didapatkan prevalensi obesitas 22,51% dan prevalensi hiperurisemia 18,2%. Didapatkan hubungan yang bermakna antara konsumsi purin tinggi (RP 13,27; IK 95% 6,79-25,88; p < 0,001) dan obesitas (RP 3,32; IK 95% 2,11-5,23; p < 0,001) dengan hiperurisemia. Pada analisis multivariat didapatkan faktor risiko independen hiperurisemia adalah konsumi purin tinggi (OR 26,72; IK 95% 11,69-61,04; p < 0,001) dan obesitas ( OR 4,06; IK 95% 1,81-9,12; p = 0,001).

Simpulan: Terdapat hubungan yang bermakna antara konsumsi purin tinggi dengan hiperurisemia pada penduduk suku Bali di kota Denpasar.
Kadar interleukin 6 serum sebagai prediktor luaran rawat inap pada lanjut usia di desa Pedawa Buleleng Bali
Authors: Semaradana Wayan Giri Putra , Suka Aryana I Gusti Putu , Tuty Kuswardhani RA , Astika I Nyoman , Putrawan Ida Bagus , Rai Purnami Ni Ketut
Published: August 2019

Latar Belakang: Angka rawat inap semakin meningkat seiring pertambahan usia sehingga meningkatkan biaya kesehatan. Salah satu faktor risikonya adalah adanya immunosenescence. Inflamasi kronik merupakan penyebab dari immunosenescence dan dapat ditandai dengan peningkatan serum interleukin 6.

Tujuan: Mengetahui apakah kadar interleukin 6 (IL-6) serum merupakan prediktor terjadinya luaran rawat inap pada lanjut usia.

Metode: Penelitian ini merupakan studi prospektif analitik dengan jumlah sampel sebanyak 76 orang lanjut usia (usia ≥ 60 tahun) di Desa Pedawa Buleleng Bali yang diambil secara stratified random sampling. Pemeriksaan IL-6 kadar serum memakai reagen Quantikine HS Human IL-6 Immonoassay dengan satuan pg/mL. Luaran rawat inap diobservasi selama 6 bulan. Analisis data berupa deskriptif, bivariat (uji komparasi dan uji tabulasi silang) dan analisis multivariat yang menggunakan regresi logistik.

Hasil: Rerata kadar IL-6 serum didapatkan 2,8 ±4,09 pg/mL. Dari hasil observasi selama 6 bulan, didapatkan subyek yang mengalami luaran rawat inap sebanyak 12 orang (15,8%). Perbedaan rerata kadar IL-6 serum yang siginifikan didapatkan antara kelompok yang mengalami rawat inap (IK 95%; p <0,01) dibandingkan dengan yang tidak. Hasil regresi logistik menunjukkan bahwa kadar IL-6 serum tetap mempengaruhi terjadinya luaran rawat inap setelah mengendalikan variabel perancu (IK 95%; p <0,01). Uji chi-square menunjukkan subyek dengan kadar IL-6 serum tinggi mempunyai resiko relatif mengalami luaran rawat inap sebesar 18,8 (IK 95%; p <0,01).

Simpulan: Kadar IL-6 serum yang tinggi merupakan prediktor luaran rawat inap lanjut usia.
Korelasi antara kadar hemoglobin dengan status kognitif pada pasien geriatri di RSUP Sanglah
Authors: Nopriantha Made , Kuswardhani RA Tuty
Published: August 2019

Latar Belakang : Pada pasien Geriatri terjadi penurunan kadar hemoglobin seiring pertambahan usia. Pada keadaan anemia akan timbul kondisi hipoksik sehingga akan mempengaruhi tidak hanya fungsi fisik tetapi juga fungsi kognitif.

Tujuan : Untuk mengetahui korelasi antara kadar hemoglobin dan status kognitif pada pasien geriatri di RSUP Sanglah

Metode: Penelitian ini merupakan analisa potong lintang. Data diambil dari rekam medis pasien Geriatri (umur > 60 tahun) yang dirawat di RSUP Sanglah dari Mei-Juli 2017. Anemia ditentukan berdasarkan kriteria klinis (hemoglobin < 10 gr/dl) dan status kognitif ditentukan berdasarkan Mini-Mental State Examination (MMSE). Uji pearson digunakan untuk mengetahui korelasi antara 2 variabel numerik dengan distribusi normal. Data secara statistik signifikan bila p < 0,05.

Hasil: Total 78 pasien diikutsertakan dalam penelitian ini dimana memuat 37,4% pria dan 52,6% wanita. Prevalensi gangguan kognitif pada pasien geriatri sebesar 41% dan tidak didapatkan perbedaan signifikan berdasarkan umur dan jenis kelamin. Terdapat korelasi antara kadar hemoglobin dan status kognitif pada pasien geriatric. Uji regresi linear menunjukkan umur dan kadar hemoglobin mempengaruhi status kognitif pada pasien geriatri.

Simpulan: . Terdapat korelasi antara kadar hemoglobin dan status kognitif pada pasien geriatri.
Satu tahun kesintasan penderita limfoma non-hodgkin berdasarkan klasifikasi histopatologi working formulation
Authors: Ludirdja Evan Pratama , Rena Ni Made Renny Anggreni , Suega Ketut , Bakta Made
Published: August 2019

Latar belakang: Limfoma Non-Hodgkin (LNH) memiliki manifestasi dan gambaran histologi yang heterogen. Berdasarkan klasifikasi Working Formulation, LNH dibagi menjadi 3, yaitu derajat keganasan rendah, menengah, dan tinggi, yang mencerminkan derajat agresifitas LNH berdasarkan gambaran histopatologiknya. Pada beberapa studi dikatakan LNH tipe indolen cenderung tumbuh lambat dan memiliki kesintasan lebih panjang dibanding tipe yang lebih agresif

Tujuan: Membandingkan median kesintasan penderita LNH dari jenis sel B berdasarkan derajat keganasannya sesuai dengan klasifikasi Working Formulation

Metode: Penelitian ini menggunakan desain kohort retrospektif, antara bulan Januari 2013 sampai Juli 2017 di RSUP Sanglah Denpasar. Analisis menggunakan Kaplan meier dan seluruh data dianalisis menggunakan SPSS.

Hasil: Dari 88 penderita LNH, diambil 38 subyek yang eligible. Dari data didapatkan sebanyak 21 penderita (55,3%) berjenis kelamin laki-laki, dengan gambaran histopatologi terbanyak berupa Diffuse Large Cell (36,8%). Sebanyak 3 penderita (7,9%) termasuk dalam derajat keganasan rendah, 25 penderita (65,8%) termasuk dalam derajat keganasan menengah, dan 10 penderita (26,3%) dengan derajat keganasan tinggi. Median kesintasan pada LNH derajat keganasan rendah di atas 1 tahun (IK 95%), derajat keganasan menengah 271 hari (IK 95%), dan derajat keganasan tinggi 31 hari (0-72,837, IK 95%), dengan nilai p=0,133, namun kelompok dengan derajat keganasan tinggi cenderung memiliki kesintasan yang lebih rendah dibanding 2 kelompok yang lain.

Simpulan: Tidak terdapat perbedaan yang signifikan kesintasan penderita LNH dengan derajat keganasan rendah, sedang, dan tinggi.
Installation of -SO2F groups onto primary amides
Authors: Liu Jing , Wang Shi-Meng , Alharbi Njud S , Qin Hua-Li
Published: August 2019

A protocol of SO2F2-mediated installation of sulfonyl fluoride onto primary amides has been developed providing a new portal to sulfur(VI) fluoride exchange (SuFEx) click chemistry. The generated molecules contain pharmaceutically important amide and -SO2F moieties for application in the discovery of new therapeutics.
Light-curve Modeling of Fast-evolving Supernova KSN 2015K: Explosion in Circumstellar Matter of a Super-AGB Progenitor
Authors: Tolstov Alexey , Nomoto Ken’ichi , Sorokina Elena , Blinnikov Sergei , Tominaga Nozomu , Taniguchi Yoshiaki
Published: August 2019

Recent supernova searches revealed a number of fast-evolving luminous transients. We perform radiation-hydrodynamic simulations of light curves of several models of supernova from super-asymptotic giant branch (super-AGB, SAGB) stars with low-mass envelopes (M
env ∼ 0.05–1.25 M
⊙). The differences in the light curves found among the models are used to link the observed events to the most appropriate models. In particular, we propose that KSN 2015K is an electron-capture supernova. We assume an “optically” thick circumstellar medium (CSM) around SAGB and the circumstellar interaction powers the peak luminosity of the light curve with a short rise time. The faint tail might be influenced by the spin-down luminosity of a newborn Crab-like pulsar. Our fits indicate an ejecta mass of 0.02–0.05 M
⊙, a CSM mass of 0.10–0.12 M
⊙, a radius of the CSM photosphere ∼1014 cm, a kinetic energy of ∼3 × 1050 erg, a photospheric velocity v
ph ≳ 10,000 km s−1, and a pulsar total spin energy (2.5–4) × 1049 erg.
Modeling C-shock Chemistry in Isolated Molecular Outflows
Authors: Burkhardt Andrew M. , Shingledecker Christopher N. , Gal Romane Le , McGuire Brett A. , Remijan Anthony J. , Herbst Eric
Published: August 2019

Shocks are a crucial probe for understanding the ongoing chemistry within ices on interstellar dust grains, where many complex organic molecules (COMs) are believed to be formed. However, previous work has been limited to the initial liberation into the gas phase through nonthermal desorption processes such as sputtering. Here we present results from the adapted three-phase gas-grain chemical network code nautilus, with the inclusion of additional high-temperature reactions, nonthermal desorption, collisional dust heating, and shock physics parameters. This enhanced model is capable of reproducing many of the molecular distributions and abundance ratios seen in our prior observations of the prototypical shocked outflow L1157. In addition, we find that, among others, NH2CHO, HCOOCH3, and CH3CHO have significant post-shock chemistry formation routes that differ from those of many other COMs observed in shocks. Finally, a number of selected species and phenomena are studied here with respect to their usefulness as shock tracers in various astrophysical sources.
Ionization Mechanisms in Quasar Outflows
Authors: Hinkle Jason T. , Veilleux Sylvain , Rupke David S. N.
Published: August 2019

The various ionization mechanisms at play in active galactic nuclei (AGN) and quasars have been well studied, but relatively little has been done to separately investigate the contributions of these ionization mechanisms within the host galaxy and outflowing components. Using Gemini integral field spectroscopy data, we study the ionization properties of these two components in four nearby (z ≲ 0.2) radio-quiet Type 1 quasars. Emission-line ratios and widths are employed to identify the dominant ionization mechanisms for the host and outflow components in each object. We find that photoionization by the AGN often dominates the ionization of both gaseous components in these systems. In three cases, the outflowing gas is more highly ionized than the gas in the host, indicating that it is more strongly exposed to the ionizing radiation field of the AGN. In two objects, a positive correlation between the line widths and line ratios in the outflowing gas component indicates that shocks with velocities of order 100–500 km s−1 may also be contributing to the ionization and heating of the outflowing gas component. The line ratios in the outflowing gas of one of these two objects also suggest a significant contribution from photoionization by hot, young stars in the portion of the outflow that is closest to star-forming regions in the host galaxy component. The data thus favor photoionization by hot stars in the host galaxy rather than stars formed in the outflow itself.
Optical Reddening, Integrated H i Optical Depth, and Total Hydrogen Column Density
Authors: Liszt Harvey
Published: August 2019

Despite the vastly different angular scales on which they are measured, the integrated λ21 cm H i optical depth measured interferometrically,

, is a good proxy for the optical reddening derived from IR dust emission, with

 ∝ E(B–V)1.10 for 0.04 mag ≲ E(B–V) ≲ 4 mag. For E(B–V) ≲ 0.04 mag or

 < 0.7

, less-absorbent warm and ionized gases assert themselves and τ(H i) is a less reliable tracer of E(B–V). The

–E(B–V) relationship can be inverted to give a broken power-law relationship between the total hydrogen column density N(H) and

such that knowledge of

alone predicts N(H) with an accuracy of a factor of 1.5 (±0.18 dex) across two orders of magnitude variation of

. The

–N(H) relation is invariant under a linear rescaling of the reddening measure used in the analysis and does not depend on knowing properties of the H i such as the spin temperature.
Awakening of the Fast-spinning Accreting Be/X-Ray Pulsar A0538–66∗
Authors: Ducci Lorenzo , Mereghetti Sandro , Santangelo Andrea
Published: August 2019

A0538−66 is a Be/X-ray binary (Be/XRB) hosting a 69 ms pulsar It emitted bright X-ray outbursts with peak luminosity up to ∼1039 erg s−1 during the first years after its discovery in 1977. Since then, it was always seen in quiescence or during outbursts with L
x ≲ 4 × 1037 erg s−1. In 2018 we carried out XMM-Newton observations of A0538−66 during three consecutive orbits when the pulsar was close to periastron. In the first two observations we discovered a remarkable variability, with flares of typical durations between ∼2 and 50 s and peak luminosities up to ∼4 × 1038 erg s−1 (0.2–10 keV). Between the flares the luminosity was ∼2 × 1035 erg s−1. The flares were absent in the third observation, during which A0538−66 had a steady luminosity of 2 × 1034 erg s−1. In all observations, the X-ray spectra consist of a softer component, well described by an absorbed power law with photon index Γ1 ≈ 2–4 and N
H ≈ 1021 cm−2, plus a harder power-law component (Γ2 ≈ 0–0.5) dominating above ∼2 keV. The softer component shows larger flux variations than the harder one, and a moderate hardening correlated with the luminosity. The fast flaring activity seen in these observations was never observed before in A0538−66, nor, to the best of our knowledge, in other Be/XRBs. We explore the possibility that during our observations the source was accreting in a regime of nearly spherically symmetric inflow. In this case, an atmosphere can form around the neutron star magnetosphere and the observed variability can be explained by transitions between the accretion and supersonic propeller regimes.
Using Layperson-Delivered Cognitive-Behavioral Therapy to Address Mental Health Disparities
Authors: Winiarski Dominika A. , Rufa Anne K. , Karnik Niranjan S.
Published: August 2019

As mental health needs continue to grow globally, it is critical to address these concerns in a timely and efficient manner. Creative approaches should be developed to reduce disparities in access to mental health care in underserved and under-resourced communities. Exclusively focusing efforts on increasing the number of licensed mental health providers is not likely to yield significant improvements in mental health access as the demands generally greatly outweigh the availability of licensed providers. One alternative solution draws on experience and studies from less-resourced settings that have promoted the use of laypeople in community settings to provide evidence-based interventions. This article reviews the evidence on layperson-delivered cognitive-behavioral interventions, discusses important logistical and ethical issues, and makes suggestions for how to disseminate this model in the United States.[Psychiatr Ann.2019;49(8):353–357.]
Scottish architects, imperial identities and India’s built environment in the early twentieth century: the careers of John Begg and George Wittet
Authors: Longair Sarah
Published: August 2019

Two Scottish architects, John Begg and George Wittet, created some of the most famous of Mumbai’s landmarks and notable buildings elsewhere in India in the early twentieth century. They were also instrumental in the development of architectural education in India through their involvement with the Sir Jamshetji Jeejeebhoy School of Art. Both men made major contributions to the colonial built environment as well as to the future of the architectural profession in India. In this regard, they are highly significant but under-studied Scottish participants in the history of the British Empire. Scottish architects and their role in the shaping of imperial cities around the world have remained largely absent from much of the rich history of Scotland and empire. This article uses the examples of Begg and Wittet to analyse the career trajectories of these two Scottish architects. Through close analysis of Begg’s numerous writings, it becomes clear that in the professional sphere, Begg sought to champion the notable minority of trained British architects serving in India, and to bring their work to the attention of the metropole. In this regard, their professional identity was that of the British imperial architect, while they simultaneously maintained Scottish social and religious connections. Like many Scots before them, they forged fluid Scottish, British, and imperial identities while serving in India.
Scottish Networks and their Buildings in Van Diemen’s Land and Tasmania
Authors: King Stuart
Published: August 2019

In the 1820s an increasing number of Scottish settlers arrived in the Colony of Van Diemen’s Land (now Tasmania, Australia) to take up government land grants. At the time, they were the second largest ethnic group, after the English, and through their numbers, enterprise (typically pastoralism and trading), land ownership, and building helped shape the colonisation and Europeanisation of the island. This article outlines their influence in the built environment and proceeds to present portraits of three related Scottish-Vandemonian pastoral properties. Employing personal records and correspondence it focuses upon the motivations, ambitions, and agency of Scottish networks (familial, social and entrepreneurial) as reflected in the architecture and building of their mansions. Those networks were local, regional, and global, with active participants in Scotland, and were instrumental in the development of the mansions. The designs for these mansions (often unattributed), along with their construction, also played a role in the building of these networks. Employing the lens offered by the experience of Scottish settlers, the paper considers the interplay of empire, regions, settler networks, and buildings in Van Diemen’s Land in the first half of the nineteenth century.
National Corporate Governance Codes and IT Governance Transparency in Annual Reports
Authors: De Haes Steven , Huygh Tim , Joshi Anant , Caluwe Laura
Published: August 2019

IT governance is concerned with the oversight of IT assets, their contribution to business value and the mitigation of IT-related risks. Emerging research calls for more board level engagement in IT governance and identifies profound consequences for digitized organizations in case the board is not involved. Against this context, this article analyses how corporate governance codes are guiding boards to provide transparency on how they treat IT governance. The findings show that only the South African corporate governance code, King III, contains a significant amount of IT (governance)-related content. As a second objective, this article builds on these findings by providing an exploratory insight in the contemporary state of IT governance transparency in Belgian and South African companies. This way, the influence of the national corporate governance code on IT governance transparency is explored. The authors' findings show that South African firms tend to be more concerned with IT governance transparency in their annual reports than Belgian firms, given a comparable IT strategic role and ownership structure. Accordingly, the case is made for including more IT (governance)-related guidance in national corporate governance codes, as this might enable companies to be more transparent about their IT governance.
Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway
Authors: Hayashi Manabu , Machida Takeshi , Ishida Yumi , Ogata Yusuke , Omori Tomoko , Takasumi Mika , Endo Yuichi , Suzuki Toshiyuki , Sekimata Masayuki , Homma Yoshimi , Ikawa Masahito , Ohira Hiromasa , Fujita Teizo , Sekine Hideharu
Published: August 2019

The complement system, a part of the innate immune system, can be activated via three different pathways. In the alternative pathway, a factor D (FD) plays essential roles in both the initiation and the amplification loop and circulates as an active form. Mannose-binding lectin–associated serine proteases (MASPs) are key enzymes of the lectin pathway, and MASP-1 and/or MASP-3 are reported to be involved in the activation of FD. In the current study, we generated mice monospecifically deficient for MASP-1 or MASP-3 and found that the sera of the MASP-1–deficient mice lacked lectin pathway activity, but those of the MASP-3–deficient mice lacked alternative pathway activity with a zymogen FD. Furthermore, the results indicate that MASP-3 but not MASP-1 activates the zymogen FD under physiological conditions and MASP-3 circulates predominantly as an active form. Therefore, our study illustrates that, in mice, MASP-3 orchestrates the overall complement reaction through the activation of FD.
First-line treatment of NRAS-mutated metastatic melanoma with a MEK inhibitor
Authors: Bickel Angelika , Diem Stefan , Flatz Lukas , Stinn Björn , Siano Marco
Published: August 2019

Until recently, standard treatment for advanced melanoma comprised basically dacarbazine and interleukin-2, leading to low response rates and significant toxicity. These days, new treatments such as immunotherapy (anti-CTLA4 and anti-PD1 antibodies) and targeted therapy with BRAF/MEK-inhibitor combinations for patients harboring a BRAF mutation are available. In BRAF wild-type patients harboring an NRAS mutation, not fit for immunotherapy treatment options are still dismal. We describe an 84-year-old patient with widespread metastatic melanoma. He presented in July 2015 with a cerebral hemorrhage under anticoagulation for atrial fibrillation. Computed tomography revealed extensive metastatic disease (liver, lung, bones, lymph nodes, heart, and brain). Molecular testing was negative for BRAF but showed the presence of an NRAS mutation in exon 3 (pQ61K [c.181C>A]). The patient received as first-line treatment two cycles of cobimetinib showing a good partial remission and manageable side effects.
Spectrality of a Class of Moran Measures
Authors: Chen Ming-Liang , Liu Jing-Cheng , Su Juan , Wang Xiang-Yang
Published: August 2019

Let $\{M_{n}\}_{n=1}^{\infty }$ be a sequence of expanding matrices with $M_{n}=\operatorname{diag}(p_{n},q_{n})$, and let $\{{\mathcal{D}}_{n}\}_{n=1}^{\infty }$ be a sequence of digit sets with ${\mathcal{D}}_{n}=\{(0,0)^{t},(a_{n},0)^{t},(0,b_{n})^{t},\pm (a_{n},b_{n})^{t}\}$, where $p_{n}$, $q_{n}$, $a_{n}$ and $b_{n}$ are positive integers for all $n\geqslant 1$. If $\sup _{n\geqslant 1}\{\frac{a_{n}}{p_{n}},\frac{b_{n}}{q_{n}}\}<\infty$, then the infinite convolution $\unicode[STIX]{x1D707}_{\{M_{n}\},\{{\mathcal{D}}_{n}\}}=\unicode[STIX]{x1D6FF}_{M_{1}^{-1}{\mathcal{D}}_{1}}\ast \unicode[STIX]{x1D6FF}_{(M_{1}M_{2})^{-1}{\mathcal{D}}_{2}}\ast \cdots \,$ is a Borel probability measure (Cantor–Dust–Moran measure). In this paper, we investigate whenever there exists a discrete set $\unicode[STIX]{x1D6EC}$ such that $\{e^{2\unicode[STIX]{x1D70B}i\langle \unicode[STIX]{x1D706},x\rangle }:\unicode[STIX]{x1D706}\in \unicode[STIX]{x1D6EC}\}$ is an orthonormal basis for $L^{2}(\unicode[STIX]{x1D707}_{\{M_{n}\},\{{\mathcal{D}}_{n}\}})$.
Building-like geometries of finite Morley rank
Authors: Müller Isabel , Tent Katrin
Published: August 2019

For any

n \geq 6

we construct almost strongly minimal geometries of type

\bullet \overset{n}{-} \bullet \overset{n}{-}\bullet

which are 2-ample but not 3-ample.
Spin-off flourishing: a new way for entrepreneurship education through experiential learning processes.
Authors: Ribeiro Artur Tavares Vilas Boas , Krakauer Patrícia Viveiros de Castro , Bonilha Eduardo , Plonski Guilherme Ary
Published: August 2019

This study analyzes the emergence of an experiential learning program focused on final undergraduate projects in Engineering and Applied Sciences. The analyzed program is oriented to provide active learning experiences in which students were responsible for directing their final project towards transforming them into nascent technology-based companies. This exploratory and qualitative case study focused on the students' analysis of (i) the perception about the learning processes, (ii) the motivation to continue with the business, (iii) the engagement with knowledge involved in the final project (iv) the relationship with the technology-based entrepreneurship subject. Seeking to present new frontiers in experiential learning, the findings of the present paper show the positive impact of experiential learning on students’ motivations and results when it comes to creating a technology-based venture, reinforcing the premises of Kolb and others. This study contributes by providing a detailed description of an entrepreneurship education program in Brazil, and also by offering more arguments towards the use of experience-based learning in undergraduate studies.
Mudança organizacional e as reações dos servidores após a implantação do REUNI
Authors: Abreu Rafael Matias de , Marra Adriana Ventola
Published: August 2019

O principal objetivo deste estudo foi identificar e analisar as reações dos servidores às mudanças ocorridas pela implantação do REUNI em uma universidade federal. Após 10 anos de inicio da implantação do Programa de Reestruturação e Expansão das Universidades Federais (REUNI), muitas mudanças ainda se percebem em curso nestas instituições. A fim de alcançar tal objetivo foi realizado um estudo de caso em uma Universidade Federal que, com o advento do REUNI, transformou sua escola técnica vinculada em campus universitário. Os dados foram coletados por meio de 61 questionários e 14entrevistas semiestruturadas com servidores pertencentes ao quadro funcional de antes da mudança ocorrida. As análises foram por estatística descritiva e análise de conteúdo. Os resultados indicaram que as mudanças ocorreram nas perspectivas apontadas por Motta (2001): estratégica, estrutural, tecnológica, humana, cultural e política. Não existiu uma comunicação eficiente por parte dos gestores da mudança, e também houve participação pequena do servidor no planejamento. Não se observaram resistências ativas durante o processo de mudança diante do contexto apresentado, mas sim a aceitação à mudança por parte dos servidores pesquisados.
The Liberalization and Management of Capital Flows - An Institutional View
Authors:   International Monetary Fund
Published: August 2019

Capital flows have increased significantly in recent years and are a key aspect of the global monetary system. They offer potential benefits to countries, but their size and volatility can also pose policy challenges. The Fund needs to be in a position to provide clear and consistent advice with respect to capital flows and policies related to them. In 2011, the International Monetary and Financial Committee (IMFC) called for ?further work on a comprehensive, flexible, and balanced approach for the management of capital flows.? This paper proposes an institutional view to underpin this approach, drawing on earlier Fund policy papers, analytical work, and Board discussions on capital flows.