bluuebunny/crossref_metadata_2025 huggingface dataset:
Perjalanan Klinis Pasien Leukemia Limfoblastik Akut dengan Kromosom Ph-Positif (Philadelphia Chromosome)
Authors: Mulatsih Sri , Ritonga Serasiamy
Published: June 2022

Penderita leukemia limfoblastik akut (LLA) dengan kromosom philadelphia secara umum mempunyai luaran terapi yang buruk. Dilaporkan perjalanan klinis penderita LLA anak dengan Ph-positif. Pasien laki-laki usia 6 tahun, datang dengan jumlah leukosit 102.000/ul. Hasil pemeriksaan fusi gena menunjukkan Ph-positif (BCR-ABL tipe LLA), sehingga pasien didiagnosis sebagai LLA risiko tinggi. Pasien berhasil mencapai remisi fase induksi, namun mengalami relaps saat fase reinduksi (minggu 17), sehingga diulang terapi dari awal. Dalam fase rumatan awal, penderita mengalami sepsis, batuk-batuk, dan ada massa di punggung. Diagnosis saat itu adalah adanya keganasan sekunder malignant peripheral nerve sheath tumor, dengan penyebaran ke paru dan hati. Pasien meninggal karena gagal napas akibat metastasis paru.Kata kunci: leukemia, philadelphia, kromosom
Myxoma of the appendix in the postpartum period in the practice of a gynecologist
Authors:   he Perinatal Center named after prof. G.S. Postol under Health Ministry of the Khabarovsk Krai, Kolesnikov Yu.N. , Kolesnikova A.A. ,   Immunorehabilitation Center, Pavlov A.E. ,   Khabarovsk Krai Clinical Hospital  No.1 named after professor S.I. Sergeev under Health Ministry of Khabarovsk Krai, Stupak M.V. ,   The Perinatal Center named after prof. G.S. Postol under Health Ministry of the Khabarovsk, Olferuk E.A. ,   The Perinatal Center named after prof. G.S. Postol under Health Ministry of the Khabarovsk Krai, Muravieva O.A. ,   The Perinatal Center named after prof. G.S. Postol under Health Ministry of the Khabarovsk Krai, Chizhova G.V. ,   Postgraduate Institute for Public Health Workers under Health Ministry of Khabarovsk Krai
Published: June 2022

Myxoma (mucocele) of the appendix is a cyst of the appendix containing mucus of various consistency (from watery to jelly-like) with chronic inflammation of the appendix with cicatricial narrowing of the base of the appendix, compression and obliteration of its lumen. It is a rare peculiar neoplasm of the appendix, and occurs in 0.02–0.5 % of all appendectomy, common in women of reproductive age. Myxoma is often found as an incidental, asymptomatic finding in 25 % of cases. The diagnosis of myxoma of the appendix is established only intraoperatively. Currently, the most precise method for the diagnosis and treatment of benign myxoma is laparoscopy. This article presents a clinical case of appendix myxoma diagnosed in a patient in the postpartum period, in which the method of laparoscopic salpingectomy and appendectomy was applied to verify the diagnosis and treatment. This clinical case once again proves that there are no certain pathognomonic signs characteristic of appendix myxoma, including in the postpartum period, therefore, careful history taking, in-depth diagnostic examination methods (ultrasound, CT, MRI) and timely use in the diagnosis of laparoscopic methods in patients with appendix myxoma. This will make it possible to competently conduct differential diagnostics, avoid errors, both in diagnosis and in the treatment of these patients, reduce the stay in a hospital bed, and thereby, most importantly, improve the quality of life of a woman
On the economic and demographic problems of the Khabarovsk Krai
Authors:   Postgraduate Institute for Public Health Workers under Health Ministry of Khabarovsk Krai, Korablev V.N.
Published: June 2022

In the article, the author analyzes some indicators of the socioeconomic development of the Far East, including the Khabarovsk Krai as a typical subject, and related demographic problems. The study made it possible to identify a number of accumulated risks: a weakening of economic activity, a low level of investment in fixed assets, a high level of public debt, a low level of income of the population; the rapid outflow of the population, which is dominated by migration loss; a high level of natural population loss, which has been growing in recent years due to low birth rates and high mortality; a combination of a decline in the number of women of childbearing age and a low total fertility rate; the formation of a regressive type of population in the form of a decrease in the population in the group younger than working age and working age group, and, conversely, an increase in number of people older than working age; shorter than in Russia as a whole, the average life expectancy of the population. The author concludes that the development of the Russian Far East can only take place under state patronage through public investment through federal targeted programs
PENGARUH KEPEMILIKAN INSTITUSIONAL, UKURAN, UMUR PERUSAHAAN DAN PROFITABILITAS TERHADAP KINERJA INTELLECTUAL CAPITAL SEKTOR KEUANGAN
Authors: Khasanah Dewi
Published: June 2022

Penelitian ini bertujuan untuk mengetahui apakah terdapat pengaruh kepemilikan institusional, ukuran, umur perusahaan dan profitabilitas terhadap kinerja intellectual capital pada sektor keuangan yang terdaftar di Bursa Efek Indonesia (BEI) tahun 2017-2019. Sampel penelitian ini terdiri dari perusahaan sektor keuangan yang telah go public dan jumlah data yang sesuai dengan kriteria sampel sebanyak 210 data terdiri dari 70 perusahaan. Penenelitian ini menggunakan regresi data panel dengan program eviews 10 untuk menguji pengaruh dari masing-masing variabel independen dengan dependen. Hasil dari penelitian menunjukkan bahwa kepemilikan institusional, ukuran, umur dan profitabilitas tidak berpengaruh terhadap kinerja intellectual capital. Selain itu, penelitian ini juga tidak dapat mendukung dari teori yang dikemukakan oleh Wernerfelt (1984), yaitu resources based-theory.
PERGANTIAN AUDITOR SEBAGAI UPAYA MENJAGA INDEPENDENSI
Authors:   STIE Malangkuçeçwara Malang Indonesia, Fathonah Annisa Dini , Djuharni Darti ,   STIE Malangkuçeçwara Malang Indonesia, Sonhaji Sonhaji ,   STIE Malangkuçeçwara Malang Indonesia
Published: June 2022

Research Purposes. This study aims to examine and analyze factors related to auditor replacement. Research Method. The unit of analysis in this study is all property and real estate sector companies listed on the Indonesia Stock Exchange, and 23 companies are taken as samples that meet the criteria, the total number observed is 92 in the form of annual reports for the 2016-2019 period. Data were analyzed using logistic regression analysis. Research Result and Findings. The results of this study reveal that management turnover and audit fees have no effect on auditor switching, while audit delay affects auditor switching. The results of this research are expected to be a consideration for companies in making decisions for auditor replacement.
SMART MANHOLE DETECTION
Authors:   JSPM’s Jaywantrao Sawant Polytechnic, Abhishek Ganpat Memane
Published: June 2022

Communication through web is turning out to be a smart city is that the long term goal to possess cleaner and better amenities for the society. Smart underground infrastructure is additionally an infinite feature to be considered while implementing a wise city. system monitoring plays an unlimited role to remain town clean and healthy. Since manual monitoring is incompetent, this finally finally winds up in slow handling of problems in drainage and consumes longer to resolve. To mitigate of these issues, the system employing a wireless sensor network, consisting of sensor nodes is meant. The proposed system is low cost, low maintenance, IOT based real time which alerts the managing station through message when any manhole crosses its threshold values. this method reduces the death risk of manual scavengers who clean the underground drainage and also benefits the final public.
COLORIZATION OF GRAYSCALE IMAGES IN DEEP LEARNING
Authors:   JAIN (Deemed-to-be University), D Pyngrope Angelica , Kumar Dr. Pawan ,   JAIN (Deemed-to-be University)
Published: June 2022

One of the most exciting Deep Learning applications is color grading black and white pictures. Coloring a grayscale image is a simple exercise for the human mind in general; we learn to fill in missing shades in colouring books from a young age. This task used to necessitate a large number of people involvement and complex tasks, however in the recent years, thanks to AI and Deep Learning, the entire process can be automated from start to finish. In this paper, I looked at a number of publications that presented various AI and Deep Learning methodologies. I'll go over each approach and tactic that has been utilised to investigate different Neural Networks in Deep Learning and how they may be used to achieve incredible outcomes. Throughout this paper, I'll start by incorporating whatever the researchers achieved, and I'll add a wholly separate generator model as well as some changes to the training technique, which will significantly reduce the overall size of the required dataset whilst producing remarkable outcomes. A GAN based model is proposed and trained on the COCO dataset. A new experimental model has been introduced which marks as the final model of our system. We notice a slight decrease in the loss function in the final model in comparison to the first model. The baseline model computed a loss of 7.6 % and the final model computed a loss of 6.7% which denotes that the final model produces results with higher accuracy
PENGARUH KOMBINASI DOSIS PUPUK NITROGEN DAN KOMPOS JERAMI TERHADAP PERTUMBUHAN DAN HASIL TANAMAN JAGUNG (Zea mays L.) KULTIVAR BISMA
Authors: Jaenudin Amran , Trisnaningsih Umi , Rohayati Yoyoh
Published: June 2022

This research aimed to determine: (1) the effect of a combination dose of nitrogen fertilizer and straw compost on growth and yield of corn (Zea mays L.) cultivars Bisma and (2) dose combination of nitrogen fertilizer and straw compost that gives the best results on the growth and yield of corn (Zea mays L.) cultivars Bisma. The experiment was conducted in UPTD Balai Pengembangan Benih Palawija (BPBP) at Plumbon Cirebon Jawa Barat, from March through the month of June 2015. The method used in this research was the experimental method. The experimental design used was a randomized block design (RBD). This experiment consisted of 9 combined treatment nitrogen fertilizer and straw compost, each repeated three times, so there are 27 experimental plots. The combination treatment was tested in the field are: A (50 kg urea/ha and straw compost 10 tons/ha), B (50 kg urea/ha and straw compost 15 tons/ha), C (50 kg urea/ha and straw compost 20 tons/ha), D (100 kg urea/ha and straw compost 10 tons/ha), E (100 kg urea/ha and straw compost 15 tons/ha), F (100 kg urea/ha and straw compost 20 tons/ha), G (150 kg urea/ha and straw compost 10 tons/ha), H (150 kg urea/ha and straw compost 15 tons/ha), and I (150 kg urea/ha and straw compost 20 tons/ha). The results of research showed that: (1) there are significantly effect between dose combination of nitrogen fertilizer and straw compost on plant height age of 28, 35, and 42 Days After Planting (DAP), number of leaves per plant age of 35 and 42 DAP, stem diameter age of 35 and 42 DAP , Shoot Root Ratio (SSR) age of 28, 35, and 42 DAP, N uptake, Leaf Area Index, weight without husk the best cobs per plant and per plot , and weight dry shelled per plant and per plot and (2) dry shelled weight per plot gave by the combination treatment of nitrogen fertilizer 150 kg/ha and straw compost 20 tons/ha which produces 4.66 kg/plot or the equivalent of 5.92 tons/ha, assuming 80 % effective land.
Pengaruh Kombinasi Takaran Pupuk Kandang Dan Jarak Tanam Terhadap Pertumbuhan Dan Hasil Tanaman Kangkung Darat (Ipomoea reptans)
Authors: Trisnaningsih Umi , Budirokhman Dodi , Robiansah Hary
Published: June 2022

Penelitian ini bertujuan untuk mengetahui pengaruh kombinasi takaran pupuk kandang dan jarak tanam terhadap pertumbuhan dan hasil tanaman kangkung darat (Ipomoea reptans) dan untuk mengetahui kombinasi takaran pupuk kandang dan jarak tanam yang berpengaruh baik terhadap pertumbuhan dan hasil tanaman kangkung darat. Penelitian telah dilaksanakan pada bulan November sampai dengan bulan Desember 2013 di Desa Babatan, Kecamatan Kadugede, Kabupaten Kuningan (550 m dpl) dengan curah hujan type E, suhu 28oC-36oC, pH 6,5, dan tekstur tanah lempung berliat. Metode penelitian yang digunakan adalah metode eksperimen dengan Rancangan Acak Kelompok (RAK) yang terdiri dari sembilan kombinasi perlakuan: A (10 cm x 5 cm, 0 ton/ha), B (10 cm x 5 cm, 15 ton/ha), C (10 cm x 5 cm, 30 ton/ha), D (10 cm x 10 cm, 0 ton/ha), E (10 cm x 10 cm, 15 ton/ha), F (10 cm x 10 cm, 30 ton/ha), G (10 cm x 15 cm, 0 ton/ha), H (10 cm x 15 cm, 15 ton/ha), I (10 cm x 15 cm, 30 ton/ha). Variabel yang diamati adalah pertumbuhan (tinggi tanaman, jumlah daun dan diameter batang) dan hasil (bobot kotor per tanaman dan per petak, dan bobot bersih per tanaman dan per petak). Hasil penelitian menunjukkan bahwa kombinasi takaran pupuk kandang 15 ton/ha dengan jarak tanam 10 cm x 5 cm memberikan pertumbuhan dan hasil kangkung darat yang baik dibandingkan dengan kombinasi perlakuan yang lain.
Pengaruh Sarcotesta Dan Perlakuan Cahaya terhadap Viabilitas Dan Dormansi Benih Pepaya (Carica papaya L.)
Authors: Sutomo Harwan , Faqih Achmad , Mulyana Lubi
Published: June 2022

Percobaan dilaksanakan di Desa Bondan Kecamatan Sukagumiwang Kabupaten Indramayu. Lokasi tersebut berada pada ketinggian 15 meter dari permukaan laut (dpl). Waktu percobaan dimulai dari bulan Oktober sampai dengan November 2012.Rancangan percobaan yang digunakan adalah  Rancangan Acak Lengkap (RAL) dengan 6 kombinasi perlakuan dengan 4 kali ulangan. Perlakuan terdiri dari  A = S1C1  (Benih bersacrotesta dan kondisi gelap),  B = S2C1 (Benih tanpa sarcotesta dan kondisi gelap), C = S1C2 (Benih bersarcotesta dan kondisi semi terang), D = S2C2 (Benih tanpa sarcotesta dan kondisi semi terang), E = S1C3 (Benih bersarcotesta dan kondisi terang), F = S2C3 (Benih tanpa sarcotesta dan kondisi terang). Variabel yang diamati yaitu viabilitas benih, kecambah normal dan dormansi benih.Hasil penelitian menunjukkan  bahwa perlakuan sarcotesta dan cahaya berpengaruh nyata terhadap viabilitas umur pengamatan 21 hss dan 35 hss, rata-rata jumlah kecambah normal umur  pengamatan 21 hss dan 35 hss dan dormansi benih pepaya pengamatan 35 hss. Kombinasi perlakuan benih tanpa sarcotesta dan pencahayaan terang saat dikecambahkan memiliki viabilitas tertinggi, jumlah kecambah normal tertinggi dan tidak ada biji yang dormansi.
PENGARUH KOMBINASI KONSENTRASI PUPUK ORGANIK CAIR (SUPER FARM) DAN KULTIVAR TERHADAP PERTUMBUHAN DAN HASIL PAKCOY (Brassica rapa L.)
Authors: Faqih Achmad , Ameyliska Nunnik
Published: June 2022

The purpose of  this experiment the effect of liquid was to organic fertilizer (Super Farm) and cultivars on growth and yield pakcoy (Brassica rapa L.). The experiment was conducted in UPTD BPBP Plumbon Cirebon. The location is above 17 m a thigh of sea level, with soil type is regosol. The time of research was conducted on June until July.The experiments used was experimental method Randomized Design (RBD) consists of two factors and repeated three times. The first factor of the liquid organic fertilizer concentration levels: control (without POC), 1 ml/l of water, 2 ml/l of water, 3 ml/l of water, 4 ml/l of water, 5 ml/l of water. The second factor consists of two cultivars cultivar that is green and green pakcoy putsoi. The variables measured were plant height, number of leaves, plants per plot gross weight, net weight of plants per plot, gross weight per plant, and gross weight per plant.Concentration combination treatment of liquid organic fertilizer (Super Farm) and cultivars provide significant effect on the average variable plant height, number of leaves per plant, gross weight per plant, planting net weight, gross weight per plot, and the net weight per plot. Concentration combination treatment of liquid organic fertilizer (Super Farm) 2.0 ml/l of water on the cultivar Green Pakcoy and Green Putsoi can provide the best results in the net weight per plot of 8.764 kg/plot and 8.803 kg/plot, equivalent to 35.056 tons/ha and 35.212 tons/ha.
PENGARUH INTENSITAS CAHAYA TERHADAP PERTUMBUHAN DAN PERKEMBANGAN TANAMAN KACANG MERAH
Authors: Ningsih R. Siti Mustika
Published: June 2022

Red beans (Phaseolus vulgaris) is the plant that classified to the tribe papilionaceae or legums. Red beans is legume crop commodity which a lot of Indonesian people like. That process of red beans growth occur through three steps, that is germination, primary and secondary growth. Germination marked by the appearance of radicles or plumula from inside the seeds. Red beans germination marked by cotyledon removal and plumula to the ground. Elongation of red beans occur in hypocotyl. The next process is primary growth that occur the embryo growth, stem ends and root tips. The last step is secondary growth, this step is the activity of cambium that forming secondary xylem and phloem. This red beans growth can’t separate from various factors that influence one of factors that influential is light. Light is influential factor that plant needs for do photosynthesis. In the plant the more light obtained will cause obstruction growth from the plant because the light will broke the work of growth hormone (auxin). So, plant that get a good light have shorter stems than plant that doesn’t get light.
PENGARUH TAKARAN ROOTONE F DAN PANJANG SETEK PUCUK TERHADAP PERTUMBUHAN BIBIT JAMBU BIJI (Psidium guajava L.) KULTIVAR KRISTAL
Authors: Trisnaningsih Ghassani Nur , Jaenudin Amran , Wahyuni Siti
Published: June 2022

Penelitian ini bertujuan untuk mengetahui pengaruh takaran Rootone F dan panjang setek pucuk terhadap pertumbuhan bibit jambu biji (Psidium guajava L) kultivar kristal. Penelitian dilaksanakan pada bulan September sampai Desember 2018 di Waida Farm Dusun Lembang Desa Pamulihan Kabupaten Sumedang, Provinsi Jawa Barat. Metode penelitian yang digunakan yaitu menggunakan metode eksperimen dengan Rancangan Acak Lengkap (RAL) pola kombinasi, yaitu terdiri dari 12 percobaan dan diulang tiga kali. A (Panjang setek 10 cm dan takaran 0 mg/setek), B (Panjang setek 10 cm dan takaran 0,25 mg/setek), C (Panjang setek 10 cm dan 0,50/setek), D (Panjang setek 10 cm dan takaran 0,75/setek), E (Panjang setek 20 cm dan takaran 0 mg/setek), F (Panjang setek 20 cm dan takaran 0,25mg/setek), G (Panjang setek 20 cm dan 0,50 mg/setek), H (Panjang setek 20 cm dan takaran 0,75mg/setek), I (Panjang setek 30 cm dan takaran 0 mg/setek), J (Panjang setek 30 cm dan takaran 0,25 mg/setek), K (Panjang setek 30 cm dan takaran 0,50 mg/setek), L (Panjang setek 30 cm dan takaran 0,75 mg/setek). Hasil penelitian menunjukkan penggunaan takaran Rootone F dan panjang setek berpengaruh nyata terhadap jumlah tunas (umur 42, 56, 70 dan 84 HST), panjang tunas (umur 56, 70, dan 84 HST), jumlah daun (umur 42, 56, 70, dan 84 HST), Volume dan bobot akar. Hasil pengaruh yang terbaik yaitu pada perlakuan panjang setek 30 cm dan takaran Rootone F 0,50 mg dan 0,75 mg.
EMOTIONAL GEOGRAPHY OF A PRE-SERVICE ENGLISH TEACHER IN ONLINE TEACHING PRACTICUM DURING COVID-19 PANDEMIC
Authors: Astutik Ninik Tri , Hapsari Astri
Published: June 2022

Due to COVID-19 pandemic, online learning has now become a bridge to facilitate teaching practice. Emotion has received little attention in online learning and online teaching practice for a senior high school, particularly for pre-service teachers. The study attempted to investigate a pre-service teacher's emotion during her online teaching practicum by using Hargreaves's (2001) concept of emotional geography. The data were gathered from diary journals and interviews conducted over the course of a month of teaching practice in a senior high school. The narratives were analysed using a descriptive qualitative approach combined with thematic analysis. The findings show that the pre-service English teacher experienced a variety of positive and negative emotions because of understanding and misunderstanding in schools, and that these emotions gradually changed her perceptions of her teaching practice. This research offers a novelty in terms of describing how a pre-service English teacher adapted from offline to online teaching practice utilizing WhatsApp Group and Google Classroom to share materials and deliver assessments at the time of COVID-19 pandemic. Emotional resilience and good communication skills were proven to help the participant in navigating emotional geography in online teaching practice with limited faceto-face interaction and guidance with the teacher supervisor in the school.
CODE SWITCHING USED BY EMILY AS SEEN IN THE EMILY IN PARIS
Authors: Widowati Theresia Seismika , Bram Barli
Published: June 2022

Nowadays, being bilinguals when communicating with others is something familiar. Many factors can influence people to be bilinguals at the same time. By being bilinguals, people are urged to do code-switching. This study aims to answer the questions of what types of code-switching are used by the main character of Emily in Paris series and the functions of code-switching that are found in the Emily in Paris series. This study used a qualitative method and the data were collected from the script of episode 1 till episode 10 of Emily in Paris series. The results of the research showed that there were 3 types of code-switching that are used by Emily in Emily in Paris, such as inter-sentential switching, intra-sentential switching, and tag switching. Furthermore, the functions of code-switching that are usually used by Emily were 6, namely reiteration, quotation, addressee specification, interjection, message qualification, and personalization versus objectification.
EKULIAH WEBSITE FOR TEACHING WRITING DESCRIPTIVE TEXT DURING THE COVID-19 PANDEMIC SITUATION
Authors: Fauzi Arief Zul , Brilianti Dani Fitria
Published: June 2022

The teaching and learning process during the pandemic requires adjustments and the use of adequate learning alternatives in providing material to students in brave classes. This study aims to determine the effectiveness of using the ekuliah website as a learning medium for third semester students in the D-III Accounting study program at Politeknik Harapan Bersama in studying descriptive text material during the COVID-19 pandemic situation. This research is a true experimental study that uses two class groups as research objects. Pre-test was given to both class groups in order to determine the initial competencies possessed by students. The two class groups were then taught descriptive text material with different treatments. The treatment was carried out using the conventional method for the comparison class group and the use of the ekuliah website media for the experimental class group. After the post-test was held at the end of the treatment, the test results experienced a significant increase in the average score for the comparison class group of 2.4 points (mean of pre-test score was 72.6 and post-test was 75) and 6.9 points (mean of pre-test score was 76 and post-test was 82.9) for the experimental class. It can be said that learning descriptive text material for third semester students of the D-III Accounting Study Program at Politeknik Harapan Bersama using the ekuliah website is effective in improving learning outcomes.
CAN DIGITAL LITERACY PRACTICES MOTIVATE INTERNATIONAL STUDENTS TO UPGRADE THEIR ENGLISH AS A SECOND LANGUAGE (L2)?: AN ETHNOGRAPHY CASE STUDY
Authors: Valentina Tri Febrianti , Arifani Yudhi , Anwar Khoirul
Published: June 2022

This article discussed how to bridge communication between international students studying at host universities in other countries through digital literacy practices and is a model for global social interaction. This article also investigates the use of English proficiency, specifically for students in Indonesia and Thailand via online platform. It is based on semi structure interviews synchronously and asynchronously conducted with international students in both countries. The article focuses on five international students studying abroad from five different countries. This article uses an ethnography case study which describes some images from the results and findings in greater depth. The findings indicate the reasons for analysis and effectiveness in moving literacy practice toward digitalization for L2 students. These findings suggest that new literacy learning is rapidly evolving with advanced technology, necessitating the use of a high-speed Internet connection. This study contributes to language planning as L2 based on ethnography which has also been adapted into digital literacy for Thai and Indonesian students. In addition, this research's contribution is to give some people more about the importance of digital literacy practices, especially for an institution that has international students in teaching and learning. The authors' focus is on their personal experiences with digital literacy practices
Average molecular weight levels in patients with myocardial infarction against COPD depending on presence of complications in acute period
Authors: Prokofieva T. V.
Published: June 2022

Purpose. To study the levels of average molecules in patients with myocardial infarction against the background of chronic obstructive disease depending on the presence of complications in the acute period of the infarction.

Materials and methods. We studied 225 patients with STEMI. In 195 of them the MI developed against the background of COPD, and in 130 of them it was mono-inflammatory. Among mono-nososologic patients there were 85 patients with acute MI without any complications and 45 patients with complications. Among patients with COPD, 62 patients had uncomplicated MI, and 133 had complicated MI. The comparison group consisted of 110 somatically healthy individuals. Average molecules were determined according to M. Ya. Malakhova (1995) method by direct spectrometry. Statistical data processing was performed using SPSS 26.0 software package.

Results of the study. The levels of LMWP and OP in various biological fluids in patients with complicated MI were statistically significantly higher both among patients with MI as a mononosomal disease and in the presence of COPD. Patients with complications registered higher levels of catabolic pool, endogenous intoxication index and lower values of intoxication coefficient. Among MI patients without complications stage I of endogenous intoxication prevailed, and among the patients with complicated MI and with uncomplicated MI against COPD – stage II, and among the patients with complicated MI against COPD – stage III.

Conclusion. Complicated myocardial infarction is characterized by more pronounced endogenous intoxication. In comorbid patients with complicated MI, endogenous intoxication is more pronounced than in complicated MI without COPD. The demonstrability of the LMWP and OP levels allows us to recommend their use in prognostic algorithms for the development of coronary pathology in comorbid patients.
Myocardial revascularization in patients with transcatheter aortic valve implantation (TAVI) and endovascular repair of thoracic aorta
Authors: Mironov N. A. , Polyakov R. S. , Matskeplishvili S. T. , Dyachuk L. I. , Fettser D. V. , Trukhanova M. A. , Averkova A. O. , Karanadze N. A. , Arutunova Y. E.
Published: June 2022

Transcatheter aortic valve implantation is the main treatment for severe aortic stenosis in patients with high surgical risks. There are undeniable advantages such as minimally invasive access, better portability in patients and decreased risk of postoperative complications compare to open surgery. Unfortunately, most aortic stenoses have the same etiology with coronary artery diseases and it necessitates invasive treatment. Cardiac artery catheterization and providing of stable instrument position are complications in post TAVI patients. It is not always possible to perform angioplasty from diagnostic radial access in post TAVI patient and there is an option of changing access to femoral to provide more safe and stable position of instruments during manipulation.
Predictors of contrast-induced acute kidney injury in hemodynamically stable patients with myocardial infarction
Authors: Arsenicheva O. V.
Published: June 2022

The aim. To study predictors of contrast-induced acute kidney injury (CI-AKI) in hemodynamically stable patients with myocardial infarction (MI).

Materials and methods. 487 hemodynamically stable patients with MI were under observation after emergency percutaneous coronary intervention (PCI). CI-AKI was defined as an increase in the level of creatinine in the blood within 48 hours after administration of the radiopaque drug (RCP) by ≥ 26.5 mmol from the baseline level. To detect independent risk factors of CI-AKI, the method of multiple logistic regression was used.

Results. The observation group consisted of 48 patients with MI who developed CI-AKI (mean age 64.2 ± 5.18 years), the comparison group of 439 patients with MI without CI-AKI (mean age 55.6 ± 6.03 years). In the observation group were observed more often patients older than 70 years (13 [27.1 %] vs 29 [13.4 %]; p = 0.011), with arterial hypertension (45 [93.8 %] vs 329 [74.9 %]; p = 0.003), postinfarction cardiosclerosis (18 [37.5 %] vs 98 [22.3 %]; p = 0.019), glycemic level ≥ 6.1 mmol/l at admission (22 [45.8 %] vs 129 [29.4 %]; p = 0.019) and left ventricular ejection fraction ≤ 40 % (14 [29.2 %] vs 71 [16.2 %]; p = 0.024). In patients with CI-AKI, the frequency of three vascular pathologies of the coronary bed was higher (29 [60.4 %] vs 195 [44.4 %]; p = 0.035), two or more stents were implanted more often in PCI (31 [64.6 %] vs 184 [41.9 %]; p = 0.003) and the volume of сontrast volume ≥ 145 ml was used (30 [62.5 %] vs 206 [46.9 %]; p = 0.040).

Findings. The probability of CI-AKI in hemodynamically stable MI patients was associated with the level of glucose in venous blood at admission ≥ 6.1 mmol/l, the сontrast volume used ≥ 145 ml and implantation of two or more stents in emergency PCI.
Elimination of diagnostic inaccuracy of two-wave pulse oximetry in assessment of blood oxygenation in smokers
Authors: Gnoevykh V. V. , Shorokhova Yu. A. , Smirnova A. Yu. , Chernova N. G.
Published: June 2022

Transcutaneous two-wave pulse oximetry is the most popular and prevalent method for studying blood oxygenation. However, during its implementation, smokers do not take into account the level of carboxyhemoglobin, which leads to an erroneous overestimation of hemoglobin saturation with oxygen. The computer program developed by us makes it possible, without the use of additional diagnostic equipment, to correct the results of monitoring blood oxygenation for the level of carboxyhemoglobin, correcting the indicated diagnostic inaccuracy in assessing the saturation of hemoglobin by oxygen in smokers.
Evaluation of Social Integration of Syrians Under the Temporary Protection Status in the Context of Acculturation
Authors: USLU Latife
Published: June 2022

With international migrations for various reasons, the issue of post-migration integration becomes an issue that needs to be taken seriously for countries that are the target of immigration. In the context of international migration, the largest refugee migration witnessed in recent years has been the migration of refugees fleeing the war in Syria. As a result of the war that started in Syria in 2011, Turkey has started to host millions of Syrian refugees under temporary protection. But it is thought that the position of Syrians in the country has turned from temporary to permanent. At this point, the issue of integration and social cohesion for Syrians gains importance. However, it makes it necessary to open up for discussion in which direction the integration and social cohesion of Syrians will develop because of the negative perception of the local people towards Syrians, the inability to meet the needs in terms of integration and the inadequacy of migration policies. In this study, an evaluation of integration is made, especially in the context of acculturation, the subject is discussed. In this context, it is considered that the risk of Syrians becoming increasingly withdrawn and separating from society is high.
LÍDERES QUE ENFRENTAM O BURNOUT: AÇÕES QUE DESPERTAM O PROTAGONISMO DIANTE A AUTOGESTÃO DO BEM-ESTAR NO TRABALHO E NA VIDA DE QUEM CUIDA E LIDERA
Authors: Marchesini Eveline Nascimento
Published: June 2022

: This intervention project intends to act in the prevention and mitigation of Burnout in organizational leaders. Justifies the accomplishment of this work, the fact that the main diagnostic hypotheses affirm that the Burnout syndrome is a disease arising from work, being responsible for suffering and wear and tear that affect workers, since they result from uninterrupted working hours, and even of ostracism, phenomena which can aggravate the feeling of not belonging to the work team, organizational culture and values that do not match the moral and ethical principles of the worker himself (MASLACH & JACKSON, 1981). The objectives of this project, therefore, are to mitigate and prevent the main causes of Burnout syndrome in organizational leaders. As a result of the intervention, it is expected to prepare and instruct leaders about the brain, psychological and emotional mechanisms of Burnout, increasing in them a personal feeling of professional self-fulfillment and well-being at work, contemplating direct and indirect preventive strategies that have already been validated by Lipp, Nunes & Costa (2019). Methodologically, the intervention will be developed in a digital training format, called the Protagonist Journey of Well-being, and will be offered by the company Imagnis Training Professionals Ltd, focusing on leaders who understand the Portuguese language and who work in any organization.
PROJETO DE INTERVENÇÃO COM O PROTAGONISMO FAMILIAR NA PREVENÇÃO DO CONSUMO ABUSIVO DE ÁLCOOL E DROGAS
Authors:   Universidade Presbiteriana MACKENZIE, Bonatto Priscila Ferreira
Published: June 2022

The present work aims to create an intervention project for the prevention of psychotic substance use. Methodologically, the studies will be carried out, through the reading of articles, books and research, which lead to the knowledge and understanding of the factors that contribute to the abusive use of alcohol and drugs for some individuals. The research justifies the fact that this understanding goes through the understanding of the importance and influence of the environment, in which the individual is inserted, be it: school, work or social. As preliminary results, it was possible to perceive that the subject, in deserting to the use and abuse of narcotic substances, not infrequently extends the effects of this to the family and other abusive contexts for health, such as social relationships, school and professional. . As objectives of the intervention, we intend to develop strategies and map risk factors, understand and know the consequences of consumption and abusive use, as well as help families of young people and children, in order to mitigate the risk of developing addiction, especially among children and adolescents. adolescents, environmentally and emotionally vulnerable, descendants of addicted parents.
Peran Farmasis Terhadap Tingkat Kepatuhan Minum Obat, Pengetahuan, dan Tekanan Darah Pasien Hipertensi Prolanis di Puskesmas Kecamatan Pulogadung
Authors: Putri Annisa Septyana , Laksmitawati Dian Ratih , Saragi Sahat
Published: June 2022

Tujuan penelitian adalah untuk mengetahui tingkat kepatuhan minum obat, pengetahuan, dan tekanan darah pasien hipertensi prolanis sebelum dan sesudah intervensi farmasis. Metode penelitian adalah quasi eksperimental yang dilakukan secara prospektif. Populasi penelitian adalah seluruh pasien hipertensi yang datang berobat ke Puskesmas Kecamatan Pulogadung dengan jumlah sampel 39 orang. Edukasi diberikan dengan menggunakan bantuan penyebaran leaflet dan ceramah secara online yaitu dengan bantuan Google Meeting. Sedangkan untuk reminding dilakukan melalui penulisan pesan yang bersifat motivasi, reminder, jadwal minum obat, dan informasi-informasi lain yang terkait melalui Whatsapp Group. Analisis data menggunakan statistik Uji Wilcoxon, Uji Friedmaan. Hasil penelitian yaitu terdapat perbedaan yang signifikan skor pengetahuan, kepatuhan dan jumlah pil obat yang diminum responden sebelum dan setelah intervensi dengan nilai p = 0,000 (p < 0,05) dimana terdapat peningkatan skor pengetahuan sebesar 2.46, skor kepatuhan sebesar 1.1, peningkatan jumlah pil yang dikonsumsi pada bulan ke 3 menjadi 92,182. Tekanan darah diastole dan systole juga mengalami penurunan yang signifikan setelah intervensi (p = 0.000). Kesimpulan yaitu edukasi, konseling dan reminder yang dilakukan farmasis dapat meningkatkan kepatuhan minum obat, pengetahuan pasien, dan hasil tekanan darah pada pasien hipertensi prolanis
Implementasi Pemantauan Ibu Hamil Kurang Energi Kronik Dalam Upaya Percepatan Perbaikan 1000 Hari Pertama Kehidupan
Authors: Sari Rumita Ena , Ibnu Ismi Nurwaqiah , Ramadhani Ayunda
Published: June 2022

Penelitian ini bertujuan untuk mengetahui Implementasi Pemantauan Ibu Hamil KEK di Kabupaten Tanjung Jabung Timur 2021. Penelitian ini merupakan penelitian kualitatif. Informan penelitian berjumlah 9 orang dipilih dengan teknik purposive sampling. Pengumpulan data menggunakan wawancara mendalam (indepth interview), telaah dokumen dan dokumentasi. Bentuk komunikasi dituangkan dalam bentuk SK Bupati lalu di turunkan kepada Dinas Kesehatan, kemudian dari Dinas Kesehatan ke puskesmas mengadakan pertemuan yang dilakukan oleh dinas kesehatan, dan terakhir komunikasi dilakukan dari puskesmas ke sasaran yaitu ibu hamil dengan memberikan edukasi/sosialisasi seputar kehamilan. SDM dalam pemantauan ibu hamil KEK masih belum maksimal dikarenakan kurangnya tenaga ahli gizi yang sesuai dengan bidangnya yang membuat beberapa puskesmas tidak memiliki tenaga ahli gizi. Tidak adanya gudang khusus penyimpanan PMT dan obat-obatan, serta jangka waktu/masa expired PMT sangat pendek, serta jauhnya jarak pengiriman dan pendistribusian. Masih kurangnya anggaran disebabkan terjadinya pandemik Covid-19 yang membuat alokasi Anggaran dialihkan sebagian. Dalam program pemantauan ibu hamil KEK seluruh pelayanan kesehatan wajib dilaksanakan sesuai dengan SPM. Pemantauan ibu hamil KEK dilakukan setiap 2 minggu sekali. Tugas dan fungsi masing-masing tim tingkat kab/kec/puskes/desa telah tercantum dalam SK Pokja. Implementasi kebijakan pemantauan, faktor komunikasi cukup maksimal, sumber daya belum maksimal. Program wajib sesuai SPM. Program pelayanan, pembinaan serta pengawasan belum maksimal
Daya Hambat Bakteri Propionibacterium acne Gel Kombinasi Ekstrak Kulit Buah Manggis (Garcinia mangostana L.) dan Ekstrak Sari Jeruk Bali (Citrus maxima Merr)
Authors: Indah Putri Febriani Dewi , Djamil Ratna , Taurhesia Shelly , Sari Kartika
Published: June 2022

Tujuan penelitian adalah untuk mengetahui kombinasi konsentrasi sediaan gel ekstrak kulit buah manggis (Garnicia mangostana) dan ekstrak sari buah jeruk bali (Citrus maxima) dalam menghambat pertumbuhan bakteri Propionibacterium acne. Penelitian ini menggunakan metode eksperimen, ekstrak kulit buah manggis dan ekstrak sari buah jeruk bali dibuat dengan teknik maserasi menggunakan pelarut etanol 70% serta dilakukan uji parameter mutu terhadap masing-masing ekstrak dan diuji konsentrasi hambat minimumnya. Hasil penelitian yaitu kadar air pada ekstrak kulit buah manggis telah memenuhi syarat mutu ekstrak, tetapi pada ekstrak sari buah jeruk bali melebihi batas nilai kadar air tanaman obat yaitu >10%. Kadar abu masing-masing ekstrak kulit buah manggis dan ekstrak sari buah jeruk bali secara berturut-turut yaitu 25,48% dan 21,98%. Hasil penapisan fitokimia menunjukkan bahwa ekstrak kulit buah manggis dan ekstrak sari buah jeruk Bali mengandung senyawa glikosida, alkaloid, flavonoid, tanin, fenolik, terpenoid, steroid dan minyak atsiri. Ekstrak kulit buah manggis memiliki aktivitas antibakteri sebesar 12,27±0,55 mm dan ekstrak ekstrak sari buah jeruk bali memiliki aktivitas antibakteri sebesar 17,33±0,60 mm. Kesimpulan yaitu Ekstrak kulit buah manggis dan ekstrak sari buah jeruk bali dapat dibuat sediaan gel kombinasi yang memenuhi syarat gel yang baik. Gel kombinasi ekstrak kulit buah manggis dan sari buah jeruk bali  memiliki daya hambat sebesar 3,33±0,10 mm pada F8, sediaan gel kombinasi memiliki efek antibakteri yang lebih kecil jika dibandingkan dengan sediaan gel yang mengandung ekstrak tunggal masing-masing ekstrak dan tidak stabil pada penyimpanan 3 minggu pada suhu 370C
Faktor Yang Mempengaruhi Kejadian Mual Muntah Post Operasi
Authors: Cing Marta Tania Gabriel Ching , Hardiyani Tati , Hardini Deisy Sri
Published: June 2022

Efek yang tidak menyenangkan dan sering timbul setelah dilakukan operasi atau pembedahan yaitu mual dan muntah. Efek yang dapat ditimbulkan bukan hanya masalah fisiologis namun juga dapat masalah psikologis menghambat proses terapi dan memberi dampak pengingkatan beban biaya perawatan selama pasien dirawat. Adapun tujuan penelitian ini adalah untuk mengetahui factor non farmakologi apa saja yang mempengaruhi kejadian mual dan muntah post operasi. Penelitian ini bersifat kuantitatif dengan menggunakan metode crossectional. Penelitian ini melihat factor yang mempengaruhi kejadian mual dan muntah post operasi dengan menggunakan Rhodes Index Nausea, Vomiting dan Retching (Rhodes INVR), Dimana penilaian dilakukan pada 30 orang responen pada 12 jam post operasi. Hasil penelitian didapatkan bahwa terdapat 56,7% responden mengaami kejadian PONV ringan dan 43,3% mengalami PONV sedang. 66,7% responden berusia lebih dari 50 tahun, 66,7 % berjenis kelamin pria, 86,7 % tidak memiliki riwayat PONV dan 56,7% memiliki riwayat merokok. Kesimpulan yaitu jenis kelamin memiliki korelasi signifikan terhadap kejadian mual muntah post operasi. Adapun variabel usia, lama tindakan operasi, riwayat mual muntah pada operasi sebelumnya, riwayat merokok, nyeri post operasi memiliki tidak memiliki korelasi signifikan terhadap kejadian PONV
Kajian Pustaka: Penggunaan Media Digital Sebagai Alternatif Media Pendidikan Gizi pada Remaja di Masa Pandemi COVID-19
Authors: Assabila Sarah Yuliani , Linda Riski Sefrina
Published: June 2022

Pendidikan gizi menjadi salah satu upaya preventif dalam mengatasi masalah gizi remaja di Indonesia. Namun, adanya pandemi COVID-19 menghambat proses pendidikan gizi pada remaja, mengingat adanya pembatasan kegiatan tatap muka, dan remaja melaksanakan pembelajaran dari rumah. Platform atau media digital berbasis online dapat menjadi media alternatif untuk membantu proses pendidikan gizi pada remaja selama masa pandemi berlangsung. Tujuan dari kajian pustaka ini adalah memberikan gambaran terkait pemanfaatan media digital sebagai media pendidikan gizi di masa pandemi COVID-19. Proses pencarian artikel ilmiah dilakukan melalui database Google Scholar. Hasil penelitian menunjukkan bahwa media digital memiliki potensi yang besar sebagai media alternatif pendidikan gizi di masa pandemi COVID-19. Hal tersebut ditunjukkan dengan tercapainya tujuan program-program gizi yang dilaksanakan, yaitu meningkatnya pengetahuan, sikap, dan atau tindakan remaja terhadap gizi seimbang dan PHBS. Media digital yang banyak dimanfaatkan diantaranya Twitter, WhatsApp, Google Meet, Zoom Cloud Meeting, Instagram dan Website, dengan media WhatsApp menjadi media digital yang paling banyak digunakan dalam proses pendidikan dan edukasi gizi pada remaja di masa pandemi COVID-19
Hubungan Pemanfaatan Sarana Sanitasi Terhadap Kejadian Stunting Tahun 2021
Authors: Sasmita Hanum , Sapriana Sapriana , Bernike Magdalena Sitorus Sony
Published: June 2022

Tujuan dari penelitian ini adalah Untuk mengetahui faktor yang berhubungan dengan pemanfaatan sarana sanitasi terhadap kejadian stunting di wilayah kerja Puskesmas Wani Kabupaten Donggala Sulawesi Tengah tahun 2021. Jenis Penelitian ini adalah penelitian observasional analitik dengan pendekatan case control Jumlah sampel kasus sebanyak 198 ksus stunting dan control (1:1) sebanyak 198 sehingga total sampel 396 ksus stunting pada balita adalah penelitian observasional analitik dengan pendekatan case control. Hasil  penelitian ini adalah terdapat hubungan yang bermakna antara pemanfaatan sarana sanitasi dengan kejadian stunting. Untuk pemanfaatan sarana air bersih responden yang memanfaatkan memiliki 44,8% balita stunting sedangkan yang tidak memanfaatkan 87,5% memiliki balita stunting, jamban keluarga responden yang memanfaatkan memiliki 43,7% balita stunting sedangkan yang tidak memanfaatkan 78,1% memiliki balita stunting, pemanfaatan sarana cuci tangan pakai sabun responden yang memanfaatkan memiliki 3,8% balita stunting sedangkan yang tidak memanfaatkan 73,4%% memiliki balita stunting, sedangkan pengelolaan limbah cair  rumah tangga responden yang tidak memanfaatkan memiliki balita stunting 74,0% dibandingan dengan responden yang memanfaatkan memiliki balita stunting 41,4%. Dan pengelolaan sampah padat responden yang tidak memanfaatkan,  71,7% memiliki balita stunting, dan responden yang memanfaatkan, 43,4%  memiliki balita stunting. Kesimpuannya bahwa pemanfaatan sarana sanitasi memiliki hubungan yang signifikan terhadap kejadian stunting pada balita
Asuhan Gizi Terhadap Asupan, Saturasi dan Kadar Glukosa Darah Pasien Corona Virus Disease (COVID 19) Komorbid Diabetes
Authors: Hadianti Siti , Sa'pang Mertien
Published: June 2022

Tujuan dilakukan penelitian ini adalah gambaran Asuhan Gizi Terhadap Asupan, Saturasi, dan Kadar Glukosa Darah Pasien Corona Virus Disease (COVID 19) Komorbid Diabetes Melitus. Metode penelitian ini, adalah deskriptif dengan design case study. Subyek dalam studi kasus ini adalah enam pasien yang memenuhi kriteria inklusi dan eksklusi. Berdasarkan hasil pengamatan dari enam pasien diruangan ICU Covid Al-Falah setelah dilakukan asuhan gizi 5 pasien mengalami hiperglikemia dan glukosa darah tidak terkontrol. Sedangkan satu pasien gula darah terkontrol. Salah satu penyebab tidak terkontrolnya glukosa darah pada pasien Covid 19 adalah stress metabolik. Selain dari faktor stress penyebab kenaikan glukosa darah pada pasien Covid 19 adalah efek samping dari pemberian obat dexamethasone. Saturasi oksigen dari 6 pasien yang diamati stabil karena penambahan minyak jagung pada intervensi yang diberikan dan pengurangan porsi karbohidrat pada racikan makanan cair yang diberikan. Pasien COVID-19 merupakan salah satu jenis penyakit paru, maka karbohidrat harus dikurangi jumlahnya dan digantikan dengan peningkatan dari sumber lemak.  Hal ini disebabkan karbohidrat memiliki Respiratory Quotient (RQ) yang paling tinggi dibandingkan dengan protein dan lemak yang berakibat pada peningkatan retensi CO2 yang dihasilkan sehingga dapat menambah gejala sesak yang dialami oleh penderita COVID-19. Kesimpulan, Berdasarkan hasil pengamatan dari 6 pasien diruangan ICU Covid Al-Falah setelah dilakukan asuhan gizi 5 pasien mengalami hiperglikemia dan glukosa darah tidak terkontrol. Saturasi oksigen dari 6 pasien yang diamati stabil karena penambahan minyak jagung pada intervensi yang diberikan dan pengurangan porsi karbohidrat pada racikan makanan cair yang diberikan.