bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 3 from A Live-Attenuated Listeria Vaccine (ANZ-100) and a Live-Attenuated Listeria Vaccine Expressing Mesothelin (CRS-207) for Advanced Cancers: Phase I Studies of Safety and Immune Induction
Authors: Le Dung T. , Brockstedt Dirk G. , Nir-Paz Ran , Hampl Johannes , Mathur Shruti , Nemunaitis John , Sterman Daniel H. , Hassan Raffit , Lutz Eric , Moyer Bentley , Giedlin Martin , Louis Jana-Lynn , Sugar Elizabeth A. , Pons Alice , Cox Andrea L. , Levine Jordana , Murphy Aimee Luck , Illei Peter , Dubensky Thomas W. , Eiden Joseph E. , Jaffee Elizabeth M. , Laheru Daniel A.
Published: April 2023

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Supplementary Figure 2 from Adoptive Transfer of Autologous Natural Killer Cells Leads to High Levels of Circulating Natural Killer Cells but Does Not Mediate Tumor Regression
Authors: Parkhurst Maria R. , Riley John P. , Dudley Mark E. , Rosenberg Steven A.
Published: April 2023

PDF file - 149K
Supplementary Table 3 from Relationship between Quantitative GRB7 RNA Expression and Recurrence after Adjuvant Anthracycline Chemotherapy in Triple-Negative Breast Cancer
Authors: Sparano Joseph A. , Goldstein Lori J. , Childs Barrett H. , Shak Steven , Brassard Diana , Badve Sunil , Baehner Frederick L. , Bugarini Roberto , Rowley Steve , Perez Edith A. , Shulman Lawrence N. , Martino Silvana , Davidson Nancy E. , Kenny Paraic A. , Sledge George W. , Gray Robert
Published: April 2023

PDF file - 20K, Triple negative lower expression.
Supplementary Table 1 from Relationship between Quantitative GRB7 RNA Expression and Recurrence after Adjuvant Anthracycline Chemotherapy in Triple-Negative Breast Cancer
Authors: Sparano Joseph A. , Goldstein Lori J. , Childs Barrett H. , Shak Steven , Brassard Diana , Badve Sunil , Baehner Frederick L. , Bugarini Roberto , Rowley Steve , Perez Edith A. , Shulman Lawrence N. , Martino Silvana , Davidson Nancy E. , Kenny Paraic A. , Sledge George W. , Gray Robert
Published: April 2023

XLS file - 31K, Patient characteristics by GRB7 expression.
Supplementary Table 2 from Opposing Effects of Runx2 and Estradiol on Breast Cancer Cell Proliferation: In Vitro Identification of Reciprocally Regulated Gene Signature Related to Clinical Letrozole Responsiveness
Authors: Chimge Nyam-Osor , Baniwal Sanjeev K. , Luo Jingqin , Coetzee Simon , Khalid Omar , Berman Benjamin P. , Tripathy Debu , Ellis Matthew J. , Frenkel Baruch
Published: April 2023

PDF file - 90K, RT-qPCR primers used in the study.
Supplementary Figure 1 from Relationship between Quantitative GRB7 RNA Expression and Recurrence after Adjuvant Anthracycline Chemotherapy in Triple-Negative Breast Cancer
Authors: Sparano Joseph A. , Goldstein Lori J. , Childs Barrett H. , Shak Steven , Brassard Diana , Badve Sunil , Baehner Frederick L. , Bugarini Roberto , Rowley Steve , Perez Edith A. , Shulman Lawrence N. , Martino Silvana , Davidson Nancy E. , Kenny Paraic A. , Sledge George W. , Gray Robert
Published: April 2023

PDF file - 49K
Supplementary Table 1 from Population Pharmacokinetics of Busulfan in Children: Increased Evidence for Body Surface Area and Allometric Body Weight Dosing of Busulfan in Children
Authors: Trame Mirjam N. , Bergstrand Martin , Karlsson Mats O. , Boos Joachim , Hempel Georg
Published: April 2023

PDF file - 75KB, Population model comparison; population parameter estimates Abbreviations: BW body weight, BSA body surface area, CL apparent clearance, V apparent volume of distribution, ka absorption rate constant, F bioavailability, standard errors in brackets, * estimated for a 27.2 kg subject, ** CV% based on simulations (sd(Fi)/mean(Fi)) and in squared parenthesis shows the variance for the logit-transform of F.
Supplementary Figure 4 from Population Pharmacokinetics of Busulfan in Children: Increased Evidence for Body Surface Area and Allometric Body Weight Dosing of Busulfan in Children
Authors: Trame Mirjam N. , Bergstrand Martin , Karlsson Mats O. , Boos Joachim , Hempel Georg
Published: April 2023

PDF file - 612KB, AUC exposure shown by weight groups from simulations for the (A) allometric dosing regimen and (B) BSA dosing regimen with an AUCtarget of 1150�M*min; plots the 10th, 25th, 50th median, 75th and 90th percentiles as vertical boxes with error bars Abbreviations: AUC area under the curve, BSA body surface area.
Supplementary Figure 5 from MiR-1 Downregulation Cooperates with MACC1 in Promoting MET Overexpression in Human Colon Cancer
Authors: Migliore Cristina , Martin Valentina , Leoni Vera P. , Restivo Angelo , Atzori Luigi , Petrelli Annalisa , Isella Claudio , Zorcolo Luigi , Sarotto Ivana , Casula Giuseppe , Comoglio Paolo M. , Columbano Amedeo , Giordano Silvia
Published: April 2023

PDF file - 251K
Supplementary Figure 1 from Phase I, Dose-Escalation Trial of the Oral Cyclin-Dependent Kinase 4/6 Inhibitor PD 0332991, Administered Using a 21-Day Schedule in Patients with Advanced Cancer
Authors: Flaherty Keith T. , LoRusso Patricia M. , DeMichele Angela , Abramson Vandana G. , Courtney Rachel , Randolph Sophia S. , Shaik M. Naveed , Wilner Keith D. , O'Dwyer Peter J. , Schwartz Gary K.
Published: April 2023

PDF file - 124K
Supplementary Table 5 from Genome-Wide CpG Island Profiling of Intraductal Papillary Mucinous Neoplasms of the Pancreas
Authors: Hong Seung-Mo , Omura Noriyuki , Vincent Audrey , Li Ang , Knight Spencer , Yu Jun , Hruban Ralph H. , Goggins Michael
Published: April 2023

XLS file - 59K
Supplementary Table 1 from Genome-Wide CpG Island Profiling of Intraductal Papillary Mucinous Neoplasms of the Pancreas
Authors: Hong Seung-Mo , Omura Noriyuki , Vincent Audrey , Li Ang , Knight Spencer , Yu Jun , Hruban Ralph H. , Goggins Michael
Published: April 2023

XLS file - 27K
Supplementary Figure 3 from Tipping the Noxa/Mcl-1 Balance Overcomes ABT-737 Resistance in Chronic Lymphocytic Leukemia
Authors: Tromp Jacqueline M. , Geest Christian R. , Breij Esther C.W. , Elias Judith A. , van Laar Jacoline , Luijks Dieuwertje M. , Kater Arnon P. , Beaumont Tim , van Oers Marinus H.J. , Eldering Eric
Published: April 2023

PDF file - 793K, Nucleofection with Noxa siRNA or control siRNA was performed on CLL cells in the presence or absence of the proteasoom inhibitor GSI. Protein lysates were probed for Mcl-1, Noxa and �-actin. As a control, lysates of untransfected CLL cells in the presence or absence of GSI are shown.
Supplementary Figure 6 from Modulation of NOXA and MCL-1 as a Strategy for Sensitizing Melanoma Cells to the BH3-Mimetic ABT-737
Authors: Lucas Keryn M. , Mohana-Kumaran Nethia , Lau Diana , Zhang Xu Dong , Hersey Peter , Huang David C. , Weninger Wolfgang , Haass Nikolas K. , Allen John D.
Published: April 2023

PDF file - 85K, Maintenance of NOXA levels in ABT-737 treated xenografts.
Supplementary Figure 4 from Modulation of NOXA and MCL-1 as a Strategy for Sensitizing Melanoma Cells to the BH3-Mimetic ABT-737
Authors: Lucas Keryn M. , Mohana-Kumaran Nethia , Lau Diana , Zhang Xu Dong , Hersey Peter , Huang David C. , Weninger Wolfgang , Haass Nikolas K. , Allen John D.
Published: April 2023

PDF file - 1.6MB, Sensitization of MM200 and Me4405 cells in 2D culture to ABT-737 by flavopiridol.
Supplementary Figure 1 from Modulation of NOXA and MCL-1 as a Strategy for Sensitizing Melanoma Cells to the BH3-Mimetic ABT-737
Authors: Lucas Keryn M. , Mohana-Kumaran Nethia , Lau Diana , Zhang Xu Dong , Hersey Peter , Huang David C. , Weninger Wolfgang , Haass Nikolas K. , Allen John D.
Published: April 2023

PDF file - 2.3MB, Growth of NOXA-transduced melanoma cell lines in the presence or absence of serum.
Supplementary Methods from Microarray Analysis Verifies Two Distinct Phenotypes of Glioblastomas Resistant to Antiangiogenic Therapy
Authors: DeLay Michael , Jahangiri Arman , Carbonell W. Shawn , Hu Yu-Long , Tsao Sean , Tom Maxwell Wing , Paquette Jesse , Tokuyasu Taku A. , Aghi Manish K.
Published: April 2023

PDF file, 135KB, Expands upon details of the methods we used that had to be kept abbreivated for the methods section of the main manuscript.
Supplementary Figure 3 from Development and Characterization of a Novel CD19CherryLuciferase (CD19CL) Transgenic Mouse for the Preclinical Study of B-Cell Lymphomas
Authors: Scotto Luigi , Kruithof-de Julio Marianna , Paoluzzi Luca , Kalac Matko , Marchi Enrica , Buitrago Jairo Baquero , Amengual Jennifer , Shen Michael M. , O'Connor Owen A.
Published: April 2023

PDF file, 576KB, Confocal analysis of PBMC of A) wild type and B) single transgenic mice. Mature naive B cells expressing the cherry protein were observed in freshly isolated PBMC stained with a, c, e and g) DAPI, to visualize nuclei. b, d, f and h) cherry cytoplasmatic fluorescence. a, b, c and d) 40X, e, f, g and h) 63X. C) Luciferase assay of cell extracts of CD19+ B cells isolated from PBMC of wild type and single transgenic mice.
Supplementary Table 5 from Global Methylation Profiling for Risk Prediction of Prostate Cancer
Authors: Mahapatra Saswati , Klee Eric W. , Young Charles Y.F. , Sun Zhifu , Jimenez Rafael E. , Klee George G. , Tindall Donald J. , Donkena Krishna Vanaja
Published: April 2023

PDF file - 172K, Prostate cancer tissues used for methylation analysis by pyrosequencing
Supplementary Figure 1 from Phase I Study of the Combination of Sorafenib and Temsirolimus in Patients with Metastatic Melanoma
Authors: Davies Michael A. , Fox Patricia S. , Papadopoulos Nicholas E. , Bedikian Agop Y. , Hwu Wen-Jen , Lazar Alexander J. , Prieto Victor G. , Culotta Kirk S. , Madden Timothy L. , Xu Quanyun , Huang Sha , Deng Wanleng , Ng Chaan S. , Gupta Sanjay , Liu Wenbin , Dancey Janet E. , Wright John J. , Bassett Roland L. , Hwu Patrick , Kim Kevin B.
Published: April 2023

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Supplementary Table 1C from Global Methylation Profiling for Risk Prediction of Prostate Cancer
Authors: Mahapatra Saswati , Klee Eric W. , Young Charles Y.F. , Sun Zhifu , Jimenez Rafael E. , Klee George G. , Tindall Donald J. , Donkena Krishna Vanaja
Published: April 2023

PDF file - 112K, Significantly methylated genes in prostate cancer tissues from the binary group comparisons
Supplementary Table 3 from Expression of NLRR3 Orphan Receptor Gene Is Negatively Regulated by MYCN and Miz-1, and Its Downregulation Is Associated with Unfavorable Outcome in Neuroblastoma
Authors: Akter Jesmin , Takatori Atsushi , Hossain Md. Shamim , Ozaki Toshinori , Nakazawa Atsuko , Ohira Miki , Suenaga Yusuke , Nakagawara Akira
Published: April 2023

PDF file - 38KB
Supplementary Table 2 from Expression of NLRR3 Orphan Receptor Gene Is Negatively Regulated by MYCN and Miz-1, and Its Downregulation Is Associated with Unfavorable Outcome in Neuroblastoma
Authors: Akter Jesmin , Takatori Atsushi , Hossain Md. Shamim , Ozaki Toshinori , Nakazawa Atsuko , Ohira Miki , Suenaga Yusuke , Nakagawara Akira
Published: April 2023

PDF file - 30KB
Supplementary Table 1 from Expression of NLRR3 Orphan Receptor Gene Is Negatively Regulated by MYCN and Miz-1, and Its Downregulation Is Associated with Unfavorable Outcome in Neuroblastoma
Authors: Akter Jesmin , Takatori Atsushi , Hossain Md. Shamim , Ozaki Toshinori , Nakazawa Atsuko , Ohira Miki , Suenaga Yusuke , Nakagawara Akira
Published: April 2023

PDF file - 13KB
Supplementary Data from Impact of Exploratory Biomarkers on the Treatment Effect of Bevacizumab in Metastatic Breast Cancer
Authors: Jubb Adrian M. , Miller Kathy D. , Rugo Hope S. , Harris Adrian L. , Chen Dafeng , Reimann James D. , Cobleigh Melody A. , Schmidt Maike , Langmuir Virginia K. , Hillan Kenneth J. , Chen Daniel S. , Koeppen Hartmut
Published: April 2023

Supplementary Figures S1-S3; Supplementary Tables S1-S4.
Supplementary Figure 3 from Notch Signaling Promotes Growth and Invasion in Uveal Melanoma
Authors: Asnaghi Laura , Ebrahimi Katayoon B. , Schreck Karisa C. , Bar Eli E. , Coonfield Michael L. , Bell W. Robert , Handa James , Merbs Shannath L. , Harbour J. William , Eberhart Charles G.
Published: April 2023

PDF file - 1.5MB
CCR Translation for This Article from The Clinical Effect of the Dual-Targeting Strategy Involving PI3K/AKT/mTOR and RAS/MEK/ERK Pathways in Patients with Advanced Cancer
Authors: Shimizu Toshio , Tolcher Anthony W. , Papadopoulos Kyriakos P. , Beeram Muralidhar , Rasco Drew W. , Smith Lon S. , Gunn Shelly , Smetzer Leslie , Mays Theresa A. , Kaiser Brianne , Wick Michael J. , Alvarez Cathy , Cavazos Aracely , Mangold Gina L. , Patnaik Amita
Published: April 2023

CCR Translation for This Article from The Clinical Effect of the Dual-Targeting Strategy Involving PI3K/AKT/mTOR and RAS/MEK/ERK Pathways in Patients with Advanced Cancer
Supplementary Figure 4 from Targeting Tumor-Associated Endothelial Cells: Anti-VEGFR2 Immunoliposomes Mediate Tumor Vessel Disruption and Inhibit Tumor Growth
Authors: Wicki Andreas , Rochlitz Christoph , Orleth Annette , Ritschard Reto , Albrecht Imke , Herrmann Richard , Christofori Gerhard , Mamot Christoph
Published: April 2023

PDF file - 222K, Histopathological analysis of tumor sections by staining with hematoxylin and eosin (H&E). Hemorrhagic lacunae are visible in the center of tumors treated with anti-VEGFR2 ILs-dox in the Rip1Tag2 and the MMTV-PyMT tumor mouse model (top and middle rows). No hemorrhagic necroses are seen in the HT-29 xenograft tumor sections (bottom row). Scale bar = 200 �m.
Supplementary Figure 1 from Telomerase Peptide Vaccination in NSCLC: A Phase II Trial in Stage III Patients Vaccinated after Chemoradiotherapy and an 8-Year Update on a Phase I/II Trial
Authors: Brunsvig Paal Fr. , Kyte Jon Amund , Kersten Christian , Sundstrøm Stein , Møller Mona , Nyakas Marta , Hansen Gaute L. , Gaudernack Gustav , Aamdal Steinar
Published: April 2023

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Supplementary Figure 5 from Downregulation of SMG-1 in HPV-Positive Head and Neck Squamous Cell Carcinoma Due to Promoter Hypermethylation Correlates with Improved Survival
Authors: Gubanova Evgenia , Brown Brandee , Ivanov Sergei V. , Helleday Thomas , Mills Gordon B. , Yarbrough Wendell G. , Issaeva Natalia
Published: April 2023

PDF file - 1.7MB
Supplementary Figures 1-2 from Survivin Is a Viable Target for the Treatment of Malignant Peripheral Nerve Sheath Tumors
Authors: Ghadimi Markus P. , Young Eric D. , Belousov Roman , Zhang Yiqun , Lopez Gonzalo , Lusby Kristelle , Kivlin Christine , Demicco Elizabeth G. , Creighton Chad J. , Lazar Alexander J. , Pollock Raphael E. , Lev Dina
Published: April 2023

PDF file - 235K, Survivin knockdown does not impact the expression of other IAP proteins. Fig S2: Survivin KD and YM155 induce apoptosis in MPNST cells.
Supplementary Figures 1-3 from [18F]FLT–PET Imaging Does Not Always “Light Up” Proliferating Tumor Cells
Authors: Zhang Cathy C. , Yan Zhengming , Li Wenlin , Kuszpit Kyle , Painter Cory L. , Zhang Qin , Lappin Patrick B. , Nichols Tim , Lira Maruja E. , Affolter Timothy , Fahey Neeta R. , Cullinane Carleen , Spilker Mary , Zasadny Kenneth , O'Brien Peter , Buckman Dana , Wong Anthony , Christensen James G.
Published: April 2023

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Supplementary Figure 2 from Integrative Survival-Based Molecular Profiling of Human Pancreatic Cancer
Authors: Donahue Timothy R. , Tran Linh M. , Hill Reginald , Li Yunfeng , Kovochich Anne , Calvopina Joseph H. , Patel Sanjeet G. , Wu Nanping , Hindoyan Antreas , Farrell James J. , Li Xinmin , Dawson David W. , Wu Hong
Published: April 2023

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Supplementary Figure 1 from A Phase I Clinical Trial of Ad5.SSTR/TK.RGD, a Novel Infectivity-Enhanced Bicistronic Adenovirus, in Patients with Recurrent Gynecologic Cancer
Authors: Kim Kenneth H. , Dmitriev Igor , O'Malley Janis P. , Wang Minghui , Saddekni Souheil , You Zhiying , Preuss Meredith A. , Harris Raymond D. , Aurigemma Rosemarie , Siegal Gene P. , Zinn Kurt R. , Curiel David T. , Alvarez Ronald D.
Published: April 2023

PDF file - 106K, Patients were then assigned into one of three Ad5.SSTR/TK.RGD dose cohorts ranging from 1 x 109 vp/d to 1 x 1012 vp/d (6 x 107 pfu/d to 6 x 1010 pfu/d). This dose administration strategy has been validated in our preclinical studies; assigned Ad5.SSTR/TK
Supplementary Methods, Tables 1-4, Figures 1-7 from Gene Expression Differences between Colon and Rectum Tumors
Authors: Sanz-Pamplona Rebeca , Cordero David , Berenguer Antonio , Lejbkowicz Flavio , Rennert Hedy , Salazar Ramon , Biondo Sebastiano , Sanjuan Xavier , Pujana Miguel A. , Rozek Laura , Giordano Thomas J. , Ben-Izhak Ofer , Cohen Hector I. , Trougouboff Philip , Bejhar Jacob , Sova Yanina , Rennert Gad , Gruber Stephen B. , Moreno Victor
Published: April 2023

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Supplementary Figure 3 from Upregulated JAG1 Enhances Cell Proliferation in Adrenocortical Carcinoma
Authors: Simon Derek P. , Giordano Thomas J. , Hammer Gary D.
Published: April 2023

PDF file, 250KB.
Supplementary Figure 2 from Upregulated JAG1 Enhances Cell Proliferation in Adrenocortical Carcinoma
Authors: Simon Derek P. , Giordano Thomas J. , Hammer Gary D.
Published: April 2023

PDF file, 283KB.
Supplementary Figure 1 from Upregulated JAG1 Enhances Cell Proliferation in Adrenocortical Carcinoma
Authors: Simon Derek P. , Giordano Thomas J. , Hammer Gary D.
Published: April 2023

PDF file, 245KB.
Supplementary Table 1 from MicroRNA Molecular Profiles Associated with Diagnosis, Clinicopathologic Criteria, and Overall Survival in Patients with Resectable Pancreatic Ductal Adenocarcinoma
Authors: Jamieson Nigel B. , Morran Douglas C. , Morton Jennifer P. , Ali Asif , Dickson Euan J. , Carter C. Ross , Sansom Owen J. , Evans T.R. Jeffry , McKay Colin J. , Oien Karin A.
Published: April 2023

XLS file - 48K, Conventional clinicopathological parameters in PDAC cohort (n = 48) univariately associated with survival following resection.
Supplementary Figure 4 from MicroRNA Molecular Profiles Associated with Diagnosis, Clinicopathologic Criteria, and Overall Survival in Patients with Resectable Pancreatic Ductal Adenocarcinoma
Authors: Jamieson Nigel B. , Morran Douglas C. , Morton Jennifer P. , Ali Asif , Dickson Euan J. , Carter C. Ross , Sansom Owen J. , Evans T.R. Jeffry , McKay Colin J. , Oien Karin A.
Published: April 2023

PDF file - 204K, Bioinformatics enrichment of miRNAs associated with favourable outcome. A) Pathway enrichment of the targets of miR-29c, miR-30d, and miR-34a demonstrating union and intersections. B) Enrichment of focal adhesion and C) ECM-receptor interaction KEGG pathways for miR-29c, miR-30d, and miR-34a target expression.
Supplementary Figure 2 from Synergistic Action of a RAF Inhibitor and a Dual PI3K/mTOR Inhibitor in Thyroid Cancer
Authors: Jin Ning , Jiang Tianyun , Rosen David M. , Nelkin Barry D. , Ball Douglas W.
Published: April 2023

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Supplementary Figure 1 from Synergistic Action of a RAF Inhibitor and a Dual PI3K/mTOR Inhibitor in Thyroid Cancer
Authors: Jin Ning , Jiang Tianyun , Rosen David M. , Nelkin Barry D. , Ball Douglas W.
Published: April 2023

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Supplementary Table 2 from Activation of PI3K Signaling in Merkel Cell Carcinoma
Authors: Nardi Valentina , Song Youngchul , Santamaria-Barria Juan A. , Cosper Arjola K. , Lam Quynh , Faber Anthony C. , Boland Genevieve M. , Yeap Beow Y. , Bergethon Kristin , Scialabba Vanessa L. , Tsao Hensin , Settleman Jeffrey , Ryan David P. , Borger Darrell R. , Bhan Atul K. , Hoang Mai P. , Iafrate Anthony J. , Cusack James C. , Engelman Jeffrey A. , Dias-Santagata Dora
Published: April 2023

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Supplementary Table 3 from Novel Functional Germline Variants in the VEGF Receptor 2 Gene and Their Effect on Gene Expression and Microvessel Density in Lung Cancer
Authors: Glubb Dylan M. , Cerri Elisa , Giese Alexandra , Zhang Wei , Mirza Osman , Thompson Emma E. , Chen Peixian , Das Soma , Jassem Jacek , Rzyman Witold , Lingen Mark W. , Salgia Ravi , Hirsch Fred R. , Dziadziuszko Rafal , Ballmer-Hofer Kurt , Innocenti Federico
Published: April 2023

PDF file - 57K, KDR re-sequencing primers.
Supplementary Figure 5 from Novel Functional Germline Variants in the VEGF Receptor 2 Gene and Their Effect on Gene Expression and Microvessel Density in Lung Cancer
Authors: Glubb Dylan M. , Cerri Elisa , Giese Alexandra , Zhang Wei , Mirza Osman , Thompson Emma E. , Chen Peixian , Das Soma , Jassem Jacek , Rzyman Witold , Lingen Mark W. , Salgia Ravi , Hirsch Fred R. , Dziadziuszko Rafal , Ballmer-Hofer Kurt , Innocenti Federico
Published: April 2023

PDF file - 31K, Correlation of VEGFR-2 and MVD levels.
Supplementary Figure 2 from Gender Influences the Class III and V β-Tubulin Ability to Predict Poor Outcome in Colorectal Cancer
Authors: Mariani Marisa , Zannoni Gian Franco , Sioletic Stefano , Sieber Steven , Martino Candice , Martinelli Enrica , Coco Claudio , Scambia Giovanni , Shahabi Shohreh , Ferlini Cristiano
Published: April 2023

PDF file, 15KB, Bar chart showing gene expression of TUBB3 and TUBB6 in colorectal cancer cells cultured in the presence of R1881. Bar and error bars represent mean and SD of two independent experiments. Control cellswere equal to 1 and treated only with the vehicle ethanol 1%.
Supplementary Figure Legends and Table Legends from Distinct Signal Transduction Abnormalities and Erythropoietin Response in Bone Marrow Hematopoietic Cell Subpopulations of Myelodysplastic Syndrome Patients
Authors: Spinelli Elena , Caporale Roberto , Buchi Francesca , Masala Erico , Gozzini Antonella , Sanna Alessandro , Sassolini Francesca , Valencia Ana , Bosi Alberto , Santini Valeria
Published: April 2023

PDF file - 86K
Supplementary Table 1 from Defective Mismatch Repair Status as a Prognostic Biomarker of Disease-Free Survival in Stage III Colon Cancer Patients Treated with Adjuvant FOLFOX Chemotherapy
Authors: Zaanan Aziz , Fléjou Jean-François , Emile Jean-François , Des Guetz Gaëtan , Cuilliere-Dartigues Peggy , Malka David , Lecaille Cédric , Validire Pierre , Louvet Christophe , Rougier Philippe , de Gramont Aimery , Bonnetain Franck , Praz Françoise , Taïeb Julien
Published: April 2023

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Supplementary Figure 1 from Preferential Replication of Systemically Delivered Oncolytic Vaccinia Virus in Focally Irradiated Glioma Xenografts
Authors: Advani Sunil J. , Buckel Lisa , Chen Nanhai G. , Scanderbeg Daniel J. , Geissinger Ulrike , Zhang Qian , Yu Yong A. , Aguilar Richard J. , Mundt Arno J. , Szalay Aladar A.
Published: April 2023

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Related Article from microRNA-10b: A New Marker or the Marker of Pancreatic Ductal Adenocarcinoma?
Authors: Setoyama Tetsuro , Zhang Xinna , Natsugoe Shoji , Calin George A.
Published: April 2023

Related Article from microRNA-10b: A New Marker or the Marker of Pancreatic Ductal Adenocarcinoma?
Supplementary Figure 2E from Notch1 Expression, Which Is Related to p65 Status, Is an Independent Predictor of Prognosis in Colorectal Cancer
Authors: Chu Dake , Zhou Yi , Zhang Zixi , Li Yuming , Li Jipeng , Zheng Jianyong , Zhang Hongwei , Zhao Qingchuan , Wang Weizhong , Wang Rui'an , Ji Gang
Published: April 2023

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Supplementary Figure 1C from Notch1 Expression, Which Is Related to p65 Status, Is an Independent Predictor of Prognosis in Colorectal Cancer
Authors: Chu Dake , Zhou Yi , Zhang Zixi , Li Yuming , Li Jipeng , Zheng Jianyong , Zhang Hongwei , Zhao Qingchuan , Wang Weizhong , Wang Rui'an , Ji Gang
Published: April 2023

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Supplementary Figure 1 from Upregulated IL-19 in Breast Cancer Promotes Tumor Progression and Affects Clinical Outcome
Authors: Hsing Chung-Hsi , Cheng Hung-Chi , Hsu Yu-Hsiang , Chan Chien-Hui , Yeh Ching-Hua , Li Chien-Feng , Chang Ming-Shi
Published: April 2023

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Supplementary Figure 1A from Notch1 Expression, Which Is Related to p65 Status, Is an Independent Predictor of Prognosis in Colorectal Cancer
Authors: Chu Dake , Zhou Yi , Zhang Zixi , Li Yuming , Li Jipeng , Zheng Jianyong , Zhang Hongwei , Zhao Qingchuan , Wang Weizhong , Wang Rui'an , Ji Gang
Published: April 2023

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Supplementary Methods, Figures 1-9, Table 1 from rILYd4, a Human CD59 Inhibitor, Enhances Complement-Dependent Cytotoxicity of Ofatumumab against Rituximab-Resistant B-cell Lymphoma Cells and Chronic Lymphocytic Leukemia
Authors: Ge Xiaowen , Wu Lin , Hu Weiguo , Fernandes Stacey , Wang Chun , Li Xu , Brown Jennifer R. , Qin Xuebin
Published: April 2023

PDF file - 155K
Supplementary Table 3 from Targeting ALDHbright Human Carcinoma–Initiating Cells with ALDH1A1-Specific CD8+ T Cells
Authors: Visus Carmen , Wang Yangyang , Lozano-Leon Antonio , Ferris Robert L. , Silver Susan , Szczepanski Miroslaw J. , Brand Randall E. , Ferrone Cristina R. , Whiteside Theresa L. , Ferrone Soldano , DeLeo Albert B. , Wang Xinhui
Published: April 2023

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Supplementary Figure 4 from Targeting ALDHbright Human Carcinoma–Initiating Cells with ALDH1A1-Specific CD8+ T Cells
Authors: Visus Carmen , Wang Yangyang , Lozano-Leon Antonio , Ferris Robert L. , Silver Susan , Szczepanski Miroslaw J. , Brand Randall E. , Ferrone Cristina R. , Whiteside Theresa L. , Ferrone Soldano , DeLeo Albert B. , Wang Xinhui
Published: April 2023

PDF file - 170KB
Supplementary Table 2 from Loss of Transforming Growth Factor Beta Type II Receptor Increases Aggressive Tumor Behavior and Reduces Survival in Lung Adenocarcinoma and Squamous Cell Carcinoma
Authors: Malkoski Stephen P. , Haeger Sarah M. , Cleaver Timothy G. , Rodriguez Karen J. , Li Howard , Lu Shi-Long , Feser William J. , Barón Anna E. , Merrick Daniel , Lighthall Jessyka G. , Ijichi Hideaki , Franklin Wilbur , Wang Xiao-Jing
Published: April 2023

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Supplementary Figure 1E from Survival of 1,181 Patients in a Phase I Clinic: The MD Anderson Clinical Center for Targeted Therapy Experience
Authors: Wheler Jennifer , Tsimberidou Apostolia M. , Hong David , Naing Aung , Falchook Gerald , Piha-Paul Sarina , Fu Siqing , Moulder Stacy , Stephen Bettzy , Wen Sijin , Kurzrock Razelle
Published: April 2023

PDF file, 97KB, Kaplan - Meier survival curves by tumor type (gastrointestinal versus non-gastrointestinal) (n=1, 181 patients). Median survival is 12.2 months (95% CI: 10.9 - 14.0) for non-gastrointestinal tumors, and 7.4 months (95% CI: 6.6 - 8.1) for the gastrointestinal tumor (Log-rank p-value <0.0001).
Supplementary Figure and Table Legends from A Novel Aldehyde Dehydrogenase-3 Activator Leads to Adult Salivary Stem Cell Enrichment In Vivo
Authors: Banh Alice , Xiao Nan , Cao Hongbin , Chen Che-Hong , Kuo Peiwen , Krakow Trevor , Bavan Brindha , Khong Brian , Yao Mike , Ha Chi , Kaplan Michael J. , Sirjani Davud , Jensen Kristin , Kong Christina S. , Mochly-Rosen Daria , Koong Albert C. , Le Quynh-Thu
Published: April 2023

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Supplementary Figure 6 from Detection and Characterization of a Novel Subset of CD8+CD57+ T Cells in Metastatic Melanoma with an Incompletely Differentiated Phenotype
Authors: Wu Richard C. , Liu Shujuan , Chacon Jessica A. , Wu Sheng , Li Yufeng , Sukhumalchandra Pariya , Murray James L. , Molldrem Jeffrey J. , Hwu Patrick , Pircher Hanspeter , Lizée Gregory , Radvanyi Laszlo G.
Published: April 2023

PDF file - 89K, Accumulation of incompletely differentiated CD8+CD27+CD28+ effector-memory (TEM) lymphocytes co-expressing CD57 with high GB and low Perf expression in pleural effusions of metastatic breast cancer patients.
Supplementary Figure 1 from High-Risk Ovarian Cancer Based on 126-Gene Expression Signature Is Uniquely Characterized by Downregulation of Antigen Presentation Pathway
Authors: Yoshihara Kosuke , Tsunoda Tatsuhiko , Shigemizu Daichi , Fujiwara Hiroyuki , Hatae Masayuki , Fujiwara Hisaya , Masuzaki Hideaki , Katabuchi Hidetaka , Kawakami Yosuke , Okamoto Aikou , Nogawa Takayoshi , Matsumura Noriomi , Udagawa Yasuhiro , Saito Tsuyoshi , Itamochi Hiroaki , Takano Masashi , Miyagi Etsuko , Sudo Tamotsu , Ushijima Kimio , Iwase Haruko , Seki Hiroyuki , Terao Yasuhisa , Enomoto Takayuki , Mikami Mikio , Akazawa Kohei , Tsuda Hitoshi , Moriya Takuya , Tajima Atsushi , Inoue Ituro , Tanaka Kenichi
Published: April 2023

PDF file - 163K
Supplementary Materials and Methods from Local Delivery of lnterleukin-12 Using T Cells Targeting VEGF Receptor-2 Eradicates Multiple Vascularized Tumors in Mice
Authors: Chinnasamy Dhanalakshmi , Yu Zhiya , Kerkar Sid P. , Zhang Ling , Morgan Richard A. , Restifo Nicholas P. , Rosenberg Steven A.
Published: April 2023

PDF file - 138K
Supplementary Figures 1-6 from Prognostic and Predictive Role of JWA and XRCC1 Expressions in Gastric Cancer
Authors: Wang Shouyu , Wu Xuming , Chen Yansu , Zhang Jianbing , Ding Jingjing , Zhou Yan , He Song , Tan Yongfei , Qiang Fulin , Bai Jin , Zeng Jinyan , Gong Zhenghua , Li Aiping , Li Gang , Røe Oluf Dimitri , Zhou Jianwei
Published: April 2023

PDF file, 324KB.
Supplementary Methods, Figure Legends 1-5 from Mitoxantrone Inhibits HIF-1α Expression in a Topoisomerase II–Independent Pathway
Authors: Toh Yng-Miin , Li Tsai-Kun
Published: April 2023

PDF file - 97.5K
Supplementary Figure 2 from Therapeutic Effect of Lenalidomide in a Novel Xenograft Mouse Model of Human Blastic NK Cell Lymphoma/Blastic Plasmacytoid Dendritic Cell Neoplasm
Authors: Agliano Alice , Martin-Padura Ines , Marighetti Paola , Gregato Giuliana , Calleri Angelica , Prior Celia , Redrado Miriam , Calvo Alfonso , Bertolini Francesco
Published: April 2023

PDF file - 35KB
Supplementary Movie 2 from Discriminant Analysis of 18F-Fluorothymidine Kinetic Parameters to Predict Survival in Patients with Recurrent High-Grade Glioma
Authors: Wardak Mirwais , Schiepers Christiaan , Dahlbom Magnus , Cloughesy Timothy , Chen Wei , Satyamurthy Nagichettiar , Czernin Johannes , Phelps Michael E. , Huang Sung-Cheng
Published: April 2023

MOV file - 340KB
Supplementary Methods, Figure 1 from Exploring Breast Cancer Estrogen Disposition: The Basis for Endocrine Manipulation
Authors: Lønning Per E. , Haynes Ben P. , Straume Anne H. , Dunbier Anita , Helle Hildegunn , Knappskog Stian , Dowsett Mitch
Published: April 2023

Data PDF 98K
Supplementary Figure 2 from Recombinant Human Erythropoietin in Combination with Chemotherapy Increases Breast Cancer Metastasis in Preclinical Mouse Models
Authors: Hedley Benjamin D. , Chu Jenny E. , Ormond D. George , Beausoleil Michel S. , Boasie Alexandra , Allan Alison L. , Xenocostas Anargyros
Published: April 2023

PDF file - 1147KB, 2 x 106 MDA-MB-231 or MDA-MB-435 cells were injected into 6- to 7-week-old female NOD/SCID or nu/nu mice via mammary fat pad. The control cohort (n=4) received weekly saline subcutaneous injections, while three other cohorts (n=4 per group) received rHuEPO doses of 300U/kg, 600U/kg or 1200U/kg. (A-D) Data from MDA-MB-231 breast cancer cells in NOD/SCID mice. (E-H) Results from MDA-MB-435 breast cancer cells injected into nude (nu/nu) mice. (A,E) Primary tumor growth of human breast cancer cells injected into mice over time. EPO treatment was initiated at 3 weeks post injection (black arrow). Data are presented as mean � SEM. (B,F) Incidence of lung metastasis (% of mice in each treatment group that developed metastases). (C,G) Size (diameter) of lung metastases scored. Data are presented as mean � SEM. (D,H) Number of lung metastases observed. Data are presented as the mean � SEM. For all panels, # denotes a statistically significant difference relative to the untreated control cohort (p<0.05).
Supplementary Table 3 from iASPP and Chemoresistance in Ovarian Cancers: Effects on Paclitaxel-Mediated Mitotic Catastrophe
Authors: Jiang LiLi , Siu Michelle K.Y. , Wong Oscar G.W. , Tam Kai-Fai , Lu Xin , Lam Eric W-F. , Ngan Hextan Y.S. , Le Xiao-Feng , Wong Esther S.Y. , Monteiro Lara J. , Chan Hoi-Yan , Cheung Annie N.Y.
Published: April 2023

PDF file - 55K
Supplementary Table 1 from A Panel of Four miRNAs Accurately Differentiates Malignant from Benign Indeterminate Thyroid Lesions on Fine Needle Aspiration
Authors: Keutgen Xavier M. , Filicori Filippo , Crowley Michael J. , Wang Yongchun , Scognamiglio Theresa , Hoda Rana , Buitrago Daniel , Cooper David , Zeiger Martha A. , Zarnegar Rasa , Elemento Olivier , Fahey Thomas J.
Published: April 2023

PDF file - 76K
Supplementary Figure 1 from iASPP and Chemoresistance in Ovarian Cancers: Effects on Paclitaxel-Mediated Mitotic Catastrophe
Authors: Jiang LiLi , Siu Michelle K.Y. , Wong Oscar G.W. , Tam Kai-Fai , Lu Xin , Lam Eric W-F. , Ngan Hextan Y.S. , Le Xiao-Feng , Wong Esther S.Y. , Monteiro Lara J. , Chan Hoi-Yan , Cheung Annie N.Y.
Published: April 2023

PDF file - 3.1MB, (A) Confocal microscopic image of OVCA 420 cells stained with anti-iASPP antibody demonstrated that iASPP protein was predominantly expressed in cytoplasm, but small amount could be detected in the nucleus. Scale bar=50mm. (B) Immunoblot illustrated the specificity of the anti-iASPP antibody used for this study in clinical samples.
Supplementary Table 5 from Comprehensive Genome Methylation Analysis in Bladder Cancer: Identification and Validation of Novel Methylated Genes and Application of These as Urinary Tumor Markers
Authors: Reinert Thomas , Modin Charlotte , Castano Francisco M. , Lamy Philippe , Wojdacz Tomasz K. , Hansen Lise Lotte , Wiuf Carsten , Borre Michael , Dyrskjøt Lars , Ørntoft Torben F.
Published: April 2023

PDF file - 76K
Supplementary Figure 3 from Impact of the Integrin Signaling Adaptor Protein NEDD9 on Prognosis and Metastatic Behavior of Human Lung Cancer
Authors: Kondo Shunsuke , Iwata Satoshi , Yamada Taketo , Inoue Yusuke , Ichihara Hiromi , Kichikawa Yoshiko , Katayose Tomoki , Souta-Kuribara Akiko , Yamazaki Hiroto , Hosono Osamu , Kawasaki Hiroshi , Tanaka Hirotoshi , Hayashi Yuichiro , Sakamoto Michiie , Kamiya Kazunori , Dang Nam H. , Morimoto Chikao
Published: April 2023

PDF file - 107K, Gene transfer of NEDD9 renders NSCLC cells (A549 cells) chemoresistant
Supplementary Table 11 from Comprehensive Genome Methylation Analysis in Bladder Cancer: Identification and Validation of Novel Methylated Genes and Application of These as Urinary Tumor Markers
Authors: Reinert Thomas , Modin Charlotte , Castano Francisco M. , Lamy Philippe , Wojdacz Tomasz K. , Hansen Lise Lotte , Wiuf Carsten , Borre Michael , Dyrskjøt Lars , Ørntoft Torben F.
Published: April 2023

XLS file - 19.4K
Supplementary Figure 5 from Comprehensive Genome Methylation Analysis in Bladder Cancer: Identification and Validation of Novel Methylated Genes and Application of These as Urinary Tumor Markers
Authors: Reinert Thomas , Modin Charlotte , Castano Francisco M. , Lamy Philippe , Wojdacz Tomasz K. , Hansen Lise Lotte , Wiuf Carsten , Borre Michael , Dyrskjøt Lars , Ørntoft Torben F.
Published: April 2023

PDF file - 472K
Supplementary Figure 4 from Comprehensive Genome Methylation Analysis in Bladder Cancer: Identification and Validation of Novel Methylated Genes and Application of These as Urinary Tumor Markers
Authors: Reinert Thomas , Modin Charlotte , Castano Francisco M. , Lamy Philippe , Wojdacz Tomasz K. , Hansen Lise Lotte , Wiuf Carsten , Borre Michael , Dyrskjøt Lars , Ørntoft Torben F.
Published: April 2023

PDF file - 479K
Supplementary Table 3 from The Reconstruction of Transcriptional Networks Reveals Critical Genes with Implications for Clinical Outcome of Multiple Myeloma
Authors: Agnelli Luca , Forcato Mattia , Ferrari Francesco , Tuana Giacomo , Todoerti Katia , Walker Brian A. , Morgan Gareth J. , Lombardi Luigia , Bicciato Silvio , Neri Antonino
Published: April 2023

XLS file - 38K
Supplementary Figure 2 from Comprehensive Genome Methylation Analysis in Bladder Cancer: Identification and Validation of Novel Methylated Genes and Application of These as Urinary Tumor Markers
Authors: Reinert Thomas , Modin Charlotte , Castano Francisco M. , Lamy Philippe , Wojdacz Tomasz K. , Hansen Lise Lotte , Wiuf Carsten , Borre Michael , Dyrskjøt Lars , Ørntoft Torben F.
Published: April 2023

PDF file - 358K
Supplementary Figure Legend from A Phase I Dose–Escalation Study of Regorafenib (BAY 73–4506), an Inhibitor of Oncogenic, Angiogenic, and Stromal Kinases, in Patients with Advanced Solid Tumors
Authors: Mross Klaus , Frost Annette , Steinbild Simone , Hedbom Susanne , Büchert Martin , Fasol Ulrike , Unger Clemens , Krätzschmar Jörn , Heinig Roland , Boix Oliver , Christensen Olaf
Published: April 2023

PDF file, 41KB.
Supplementary Figure 2 from The Reconstruction of Transcriptional Networks Reveals Critical Genes with Implications for Clinical Outcome of Multiple Myeloma
Authors: Agnelli Luca , Forcato Mattia , Ferrari Francesco , Tuana Giacomo , Todoerti Katia , Walker Brian A. , Morgan Gareth J. , Lombardi Luigia , Bicciato Silvio , Neri Antonino
Published: April 2023

PDF file - 668K
Supplementary Figure 3 from Receptor Affinity and Extracellular Domain Modifications Affect Tumor Recognition by ROR1-Specific Chimeric Antigen Receptor T Cells
Authors: Hudecek Michael , Lupo-Stanghellini Maria-Teresa , Kosasih Paula L. , Sommermeyer Daniel , Jensen Michael C. , Rader Christoph , Riddell Stanley R.
Published: April 2023

PDF File - 125K, Supplementary Figure 3: In vitro function of T-cells expressing CD19-CARs with IgG4-Fc Hinge vs. CD8a Hinge spacer and a signaling module with 4-1BB costimulatory domain.
Supplementary Figure 3 from CLIC4, ERp29, and Smac/DIABLO Derived from Metastatic Cancer Stem–like Cells Stratify Prognostic Risks of Colorectal Cancer
Authors: Deng Yong-Jian , Tang Na , Liu Chao , Zhang Jiang-Yu , An Sheng-Li , Peng Yin-Li , Ma Li-Li , Li Guang-Qiu , Jiang Qiang , Hu Chun-Ting , Wang Ya-Nan , Liang Yao-Ze , Bian Xiu-Wu , Fang Wei-Gang , Ding Yan-Qing
Published: April 2023

PDF file - 41K, Comparison of tumor spheres metastatic potentials, invasive ability and EMT property.
Supplementary Tables 1-2 from A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen
Authors: Chia Stephen K. , Bramwell Vivien H. , Tu Dongsheng , Shepherd Lois E. , Jiang Shan , Vickery Tammi , Mardis Elaine , Leung Samuel , Ung Karen , Pritchard Kathleen I. , Parker Joel S. , Bernard Philip S. , Perou Charles M. , Ellis Matthew J. , Nielsen Torsten O.
Published: April 2023

PDF file, 68KB, Supplemental Table 1: Intrinsic subtype definitions by immunohistochemistry. Supplemental Table 2: C-Index for Risk-of-Relapse (ROR) Scores.
Supplementary Figures 1-2 from A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen
Authors: Chia Stephen K. , Bramwell Vivien H. , Tu Dongsheng , Shepherd Lois E. , Jiang Shan , Vickery Tammi , Mardis Elaine , Leung Samuel , Ung Karen , Pritchard Kathleen I. , Parker Joel S. , Bernard Philip S. , Perou Charles M. , Ellis Matthew J. , Nielsen Torsten O.
Published: April 2023

PDF file, 125KB, Supplemental Figure 1: REMARK Diagram for MA.12 Trial and Biospecimens Supplemental Figure 2: Forest plot for Disease free Survival across various Classifiers.
Supplementary Figure 1 from A Phase I Pharmacokinetic and Pharmacodynamic Study of CHR-3996, an Oral Class I Selective Histone Deacetylase Inhibitor in Refractory Solid Tumors
Authors: Banerji Udai , van Doorn Leni , Papadatos-Pastos Dionysis , Kristeleit Rebecca , Debnam Phillip , Tall Matthew , Stewart Adam , Raynaud Florence , Garrett Michelle Dawn , Toal Martin , Hooftman Leon , De Bono Johann Sebastian , Verweij Jaap , Eskens Ferry ALM
Published: April 2023

PDF file - 42K, CHR-3996
Supplementary Table S7 from Radiotherapy of Human Sarcoma Promotes an Intratumoral Immune Effector Signature
Authors: Sharma Anu , Bode Beata , Studer Gabriela , Moch Holger , Okoniewski Michal , Knuth Alexander , von Boehmer Lotta , van den Broek Maries
Published: April 2023

Supplementary Table S7 - PDF file 93K, Correlation analysis of radiotherapy-induced immunological changes in sarcoma patients: qRT-PCR analysis was performed on 37 pairs of FFPE human sarcomas for (A) immune effector cells/ molecules, (B) immune suppressor cells/ molecules, (C) effector cytokines, (D) suppressor cytokines, (E) transcription factors and (F) CT-antigens . The delta-delta Ct values were computed for each of the target genes against each other. A bivariate correlation analysis was performed and is given by the Spearman`s rho correlation coefficient (rho) and the significance by the two-tailed P value. * Correlation is significant at the 0.05 level, ** Correlation is significant at the 0.01 level. All correlations with a significant P value are in bold
Supplementary Figure 6 from Vemurafenib Synergizes with Nutlin-3 to Deplete Survivin and Suppresses Melanoma Viability and Tumor Growth
Authors: Ji Zhenyu , Kumar Raj , Taylor Michael , Rajadurai Anpuchchelvi , Marzuka-Alcalá Alexander , Chen Y. Erin , Njauw Ching-Ni Jenny , Flaherty Keith , Jönsson Göran , Tsao Hensin
Published: April 2023

PDF file, 74K, Mean survival fraction upon exposure to 10uM vemurafenib among p53 mutated and p53WT cell lines.
Supplementary Figure 4 from Vemurafenib Synergizes with Nutlin-3 to Deplete Survivin and Suppresses Melanoma Viability and Tumor Growth
Authors: Ji Zhenyu , Kumar Raj , Taylor Michael , Rajadurai Anpuchchelvi , Marzuka-Alcalá Alexander , Chen Y. Erin , Njauw Ching-Ni Jenny , Flaherty Keith , Jönsson Göran , Tsao Hensin
Published: April 2023

PDF file, 57K, Suppression of survivin levels by Nt3 (6 uM) in 4 melanoma lines.
Supplementary Table Legend from Molecular Pathways: The Complexity of the Epigenome in Cancer and Recent Clinical Advances
Authors: Conte Mariarosaria , Altucci Lucia
Published: April 2023

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Data Supplement from Comprehensive Biomarker Analysis and Final Efficacy Results of Sorafenib in the BATTLE Trial
Authors: Blumenschein George R. , Saintigny Pierre , Liu Suyu , Kim Edward S. , Tsao Anne S. , Herbst Roy S. , Alden Christine , Lee J. Jack , Tang Ximing , Stewart David J. , Kies Merrill S. , Fossella Frank V. , Tran Hai T. , Mao L. , Hicks Marshall E. , Erasmus Jeremy , Gupta Sanjay , Girard Luc , Peyton Michael , Diao Lixia , Wang Jing , Davis Suzanne E. , Minna John D. , Wistuba Ignacio , Hong Waun K. , Heymach John V. , Lippman Scott M.
Published: April 2023

Supplementary Figure 1: Heatmap of the 68 non-small cell lung cancer cell lines with EGFR wild-type used to train the Sorafenib Sensitivity Signature; Supplementary Figure 2: Heatmap of the 37 patients with EGFR mutant tumors using the Sorafenib Sensitivity signature; yes: disease control at 8 weeks; no: no disease control at 8 weeks.
Data Supplement from Comprehensive Biomarker Analysis and Final Efficacy Results of Sorafenib in the BATTLE Trial
Authors: Blumenschein George R. , Saintigny Pierre , Liu Suyu , Kim Edward S. , Tsao Anne S. , Herbst Roy S. , Alden Christine , Lee J. Jack , Tang Ximing , Stewart David J. , Kies Merrill S. , Fossella Frank V. , Tran Hai T. , Mao L. , Hicks Marshall E. , Erasmus Jeremy , Gupta Sanjay , Girard Luc , Peyton Michael , Diao Lixia , Wang Jing , Davis Suzanne E. , Minna John D. , Wistuba Ignacio , Hong Waun K. , Heymach John V. , Lippman Scott M.
Published: April 2023

Supplementary Table 3.Sorafenib-related adverse events in more than 10% of the patients.
Supplementary Figure 2 from Bridging the Gap between Preclinical and Clinical Studies Using Pharmacokinetic–Pharmacodynamic Modeling: An Analysis of GDC-0973, a MEK Inhibitor
Authors: Wong Harvey , Vernillet Laurent , Peterson Amy , Ware Joseph A. , Lee Lillian , Martini Jean-Francois , Yu Peiwen , Li Congfen , Rosario Geoffrey Del , Choo Edna F. , Hoeflich Klaus P. , Shi Yongchang , Aftab Blake T. , Aoyama Ron , Lam Sanh Tan , Belvin Marcia , Prescott John
Published: April 2023

PDF file, 83KB, Representative Western blots of ERK1/2 and total ERK1/2 of tumor tissue homogenate collected from WM-266-4 xenograft studies.
CCR Translation for This Article from A Randomized Phase II Trial of Multiepitope Vaccination with Melanoma Peptides for Cytotoxic T Cells and Helper T Cells for Patients with Metastatic Melanoma (E1602)
Authors: Slingluff Craig L. , Lee Sandra , Zhao Fengmin , Chianese-Bullock Kimberly A. , Olson Walter C. , Butterfield Lisa H. , Whiteside Theresa L. , Leming Philip D. , Kirkwood John M.
Published: April 2023

CCR Translation for This Article from A Randomized Phase II Trial of Multiepitope Vaccination with Melanoma Peptides for Cytotoxic T Cells and Helper T Cells for Patients with Metastatic Melanoma (E1602)
Supplementary Figure 2 from Acquired Resistance to Anti-VEGF Therapy in Glioblastoma Is Associated with a Mesenchymal Transition
Authors: Piao Yuji , Liang Ji , Holmes Lindsay , Henry Verlene , Sulman Erik , de Groot John F.
Published: April 2023

PDF file, 137K, Gene Set Enrichment Analysis of gene expression data of tumors before and after treatment with bevacizumab.
Supplementary Table 2 from Prevalence, Clinicopathologic Associations, and Molecular Spectrum of ERBB2 (HER2) Tyrosine Kinase Mutations in Lung Adenocarcinomas
Authors: Arcila Maria E. , Chaft Jamie E. , Nafa Khedoudja , Roy-Chowdhuri Sinchita , Lau Christopher , Zaidinski Michael , Paik Paul K. , Zakowski Maureen F. , Kris Mark G. , Ladanyi Marc
Published: April 2023

PDF file, 54K, Summary of mutations detected by clinical mutation screening and extended mass spectrometry genotyping (n=1478 tumors).
Supplementary Figure 3 from Somatic Profiling of the Epidermal Growth Factor Receptor Pathway in Tumors from Patients with Advanced Colorectal Cancer Treated with Chemotherapy ± Cetuximab
Authors: Smith Christopher G. , Fisher David , Claes Bart , Maughan Timothy S. , Idziaszczyk Shelley , Peuteman Gilian , Harris Rebecca , James Michelle D. , Meade Angela , Jasani Bharat , Adams Richard A. , Kenny Sarah , Kaplan Richard , Lambrechts Diether , Cheadle Jeremy P.
Published: April 2023

PDF - 130K, Kaplan-Meier plots of OS and PFS for patients with PIK3CA wild type or mutant tumours, that were also KRAS wild type.
Supplementary Figure 5 from EZH2-Regulated DAB2IP Is a Medulloblastoma Tumor Suppressor and a Positive Marker for Survival
Authors: Smits Michiel , van Rijn Sjoerd , Hulleman Esther , Biesmans Dennis , van Vuurden Dannis G. , Kool Marcel , Haberler Christine , Aronica Eleonora , Vandertop W. Peter , Noske David P. , Würdinger Thomas
Published: April 2023

PDF file, 45KB, DAB2IP expression in mouse models that mimic subgroup 3 and WNT.
Supplementary Figure 1 from EZH2-Regulated DAB2IP Is a Medulloblastoma Tumor Suppressor and a Positive Marker for Survival
Authors: Smits Michiel , van Rijn Sjoerd , Hulleman Esther , Biesmans Dennis , van Vuurden Dannis G. , Kool Marcel , Haberler Christine , Aronica Eleonora , Vandertop W. Peter , Noske David P. , Würdinger Thomas
Published: April 2023

PDF file, 46KB, Scatterplot of DAB2IP mRNA expression levels (arbitrary units) in patients based on medulloblastoma subgroup stratification shows that average DAB2IP expression does correlate with a specific subgroup of medulloblastoma.
Supplementary Figure 1 from Ontogeny and Sorafenib Metabolism
Authors: Zimmerman Eric I. , Roberts Justin L. , Li Lie , Finkelstein David , Gibson Alice , Chaudhry Amarjit S. , Schuetz Erin G. , Rubnitz Jeffrey E. , Inaba Hiroto , Baker Sharyn D.
Published: April 2023

PDF file, 57K, Steady-state sorafenib metabolite ratios as a function of sex.
Supplementary Table from Novel Targeting of Phospho-cMET Overcomes Drug Resistance and Induces Antitumor Activity in Multiple Myeloma
Authors: Moschetta Michele , Basile Antonio , Ferrucci Arianna , Frassanito Maria Antonia , Rao Luigia , Ria Roberto , Solimando Antonio Giovanni , Giuliani Nicola , Boccarelli Angelina , Fumarola Fabio , Coluccia Mauro , Rossini Bernardo , Ruggieri Simona , Nico Beatrice , Maiorano Eugenio , Ribatti Domenico , Roccaro Aldo M. , Vacca Angelo
Published: April 2023

PDF file, 91K, Functional analysis of differentially expressed genes in RPMI8226 or R5 cells after SU11274 treatment.
Supplementary Table Legend from Novel Targeting of Phospho-cMET Overcomes Drug Resistance and Induces Antitumor Activity in Multiple Myeloma
Authors: Moschetta Michele , Basile Antonio , Ferrucci Arianna , Frassanito Maria Antonia , Rao Luigia , Ria Roberto , Solimando Antonio Giovanni , Giuliani Nicola , Boccarelli Angelina , Fumarola Fabio , Coluccia Mauro , Rossini Bernardo , Ruggieri Simona , Nico Beatrice , Maiorano Eugenio , Ribatti Domenico , Roccaro Aldo M. , Vacca Angelo
Published: April 2023

PDF file, 80K.