bluuebunny/crossref_metadata_2025 huggingface dataset:
An integrated approach for trace detection of pollutants in water using polyelectrolyte functionalized magneto-plasmonic nanosorbents
Authors: Pinheiro Paula C. , Fateixa Sara , Daniel-da-Silva Ana L. , Trindade Tito
Published: December 2019

Resistance of pathogenic micro-organisms to conventional antibiotics is an essential issue for public health. The presence of such pharmaceuticals in aquatic ecosystems has been of major concern for which remediation and ultra-sensitive monitoring methods have been proposed. A less explored strategy involves the application of multifunctional nanosorbents for the uptake and subsequent detection of vestigial contaminants. In this study, colloidal nanoparticles (NPs) of iron oxide and gold were encapsulated in multi-layers of a charged polyelectrolyte (PEI: polyethyleneimine), envisaging the effective capture of tetracycline (TC) and its subsequent detection by Surface Enhanced Raman Scattering (SERS). Adsorption studies were performed by varying operational parameters, such as the solution pH and contact time, in order to evaluate the performance of the nanosorbents for the uptake of TC from water. While the magnetic nanosorbents with an external PEI layer (Fe3O4@PEI and Fe3O4@PEI-Au@PEI particles) have shown better uptake efficiency for TC, these materials showed less SERS sensitivity than the Fe3O4@PEI- Au nanosorbents, whose SERS sensitivity for TC in water has reached the limit of detection of 10 nM. Thus, this study highlights the potential of such magneto-plasmonic nanosorbents as multi-functional platforms for targeting specific contaminants in water, by taking into consideration both functionalities investigated: the removal by adsorption and the SERS detection across the nanosorbents’ surfaces.
Detection and functional characterization of sigma class GST in Phlebotomus argentipes and its role in stress tolerance and DDT resistance
Authors: Hassan Faizan , Singh Krishn Pratap , Ali Vahab , Behera Sachidananda , Shivam Pushkar , Das Pradeep , Dinesh Diwakar Singh
Published: December 2019

Several Glutathione S-transferases (GSTs) enzymes, in insects, have previously been implicated in resistance developed against DDT and other insecticides. The GST enzyme particularly sigma class have important physiological role in detoxification of lipid peroxidation by-products in insects.Phlebotomus argentipeshas been intensely exposed to DDT over years due to Indoor Residual Spray (IRS) programme for Kala-azar elimination in Bihar, India. However, inP. argentipes, role of GSTs in DDT resistance have not been elucidated. Here, sigma class GST ofP. argentipes(Parg-GSTσ) was successfully cloned, expressed and purified by affinity chromatography. The recombinant Parg-GSTσ was found to be highly active towards cumene hydroperoxide and 4-HNE having specific activity 92.47 & 203.92 µM/min/mg of protein, respectively and exhibited low activity towards universal substrate CDNBi.e., 8.75 µM/min/mg of protein. RT-PCR and immunoblot analysis showed at least 2 and 1.8 fold overexpression of Parg-GSTσ in the single exposed and non exposed DDT resistantP. argentipesas compared to susceptible, implicating Parg-GSTσ also involved in DDT resistance probably by imparting enhanced stress tolerance. The DDT, H2O2and temperature induction assays demonstrated stress-dependent induction of Parg-GSTσ expression indicating its important role in oxidative stress redressal.
Sarcodia suieae acetyl-xylogalactan regulate RAW 264.7 macrophage NF-kappa B activation and IL-1 beta cytokine production in macrophage polarization
Authors: Wu Tsung-Meng , Nan Fan-Hua , Chen Kuan-Chu , Wu Yu-Sheng
Published: December 2019

In this study, the effects of acetyl-xylogalactan extracted from Sarcodia suieae on RAW 264.7 macrophage polarisation were evaluated. This extracted acetyl-xylogalactan had a monosaccharide composition of 91% galactose and 9% xylose, with polysaccharide and acetyl contents of 80.6% and 19.3%, respectively. MALDI–TOF mass spectrometry and NMR spectroscopy revealed the molecular weight of the acetyl-xylogalactan to be 88.5 kDa. After acetyl-xylogalactan treatment, RAW 264.7 macrophage polarisation was noted, along with enhanced phagocytic ability. Furthermore, the Cell Counting Kit-8 (CCK-8) assay was performed and the results demonstrated non-significant alteration in lactate dehydrogenase levels in the treated cells. Next, interleukin (IL) 1β, TNF, and Malt-1 expression in RAW 264.7 macrophages treated with the S. suieae acetyl-xylogalactan was investigated through real-time quantitative polymerase chain reaction, and the results demonstrated that S. suieae acetyl-xylogalactan induced IL-1β and Malt-1 expression. RNA sequencing analysis results indicated the S. suieae acetyl-xylogalactan positively regulated cytokine production and secretion, protein secretion, and response to IL-1 activation, based on the observed GO terms. The predicted target genes in the GO enrichment analysis were found to upregulate NF-κB signalling and M0 to M1 macrophage conversion through the observed cytokine production. Thus, acetyl-xylogalactan can positively regulate RAW 264.7 macrophage polarisation.
Genetic variation drives seasonal onset of hibernation in the 13-lined ground squirrel
Authors: Grabek Katharine R. , Cooke Thomas F. , Epperson L. Elaine , Spees Kaitlyn K. , Cabral Gleyce F. , Sutton Shirley C. , Merriman Dana K. , Martin Sandra L. , Bustamante Carlos D.
Published: December 2019

Hibernation in sciurid rodents is a dynamic phenotype timed by a circannual clock. When housed in an animal facility, 13-lined ground squirrels exhibit variation in seasonal onset of hibernation, which is not explained by environmental or biological factors. We hypothesized that genetic factors instead drive variation in timing. After increasing genome contiguity, here, we employ a genotype-by-sequencing approach to characterize genetic variation in 153 ground squirrels. Combined with datalogger records (n = 72), we estimate high heritability (61–100%) for hibernation onset. Applying a genome-wide scan with 46,996 variants, we identify 2 loci significantly (p < 7.14 × 10−6), and 12 loci suggestively (p < 2.13 × 10−4), associated with onset. At the most significant locus, whole-genome resequencing reveals a putative causal variant in the promoter ofFAM204A. Expression quantitative trait loci (eQTL) analyses further reveal gene associations for 8/14 loci. Our results highlight the power of applying genetic mapping to hibernation and present new insight into genetics driving its onset.
Magnetic control of polariton spin transport
Authors: Caputo D. , Sedov E. S. , Ballarini D. , Glazov M. M. , Kavokin A. V. , Sanvitto D.
Published: December 2019

Polaritons are hybrid light–matter quasiparticles arising from the strong coupling of excitons and photons. Owing to the spin degree-of-freedom, polaritons form spinor fluids able to propagate in the cavity plane over long distances with promising properties for spintronics applications. Here we demonstrate experimentally the full control of the polarization dynamics of a propagating exciton–polariton condensate in a planar microcavity by using a magnetic field applied in the Voigt geometry. We show the change of the spin-beat frequency, the suppression of the optical spin Hall effect, and the rotation of the polarization pattern by the magnetic field. The observed effects are theoretically reproduced by a phenomenological model based on microscopic consideration of exciton–photon coupling in a microcavity accounting for the magneto-induced mixing of exciton–polariton and dark, spin-forbidden exciton states.
Flexible, low volume detection of chronobiology biomarkers from human sweat
Authors: Upasham Sayali , Thai Kevin , Muthyala Ritika , Prasad Shalini
Published: December 2019

The work demonstrates the development of a chronobiology tracking system using an affinity-based electrochemical detection modality. This serpentine electrode based system is non-invasive, label free, and economical enabling passive sweat tracking.
A high-throughput and high peak capacity narrow-bore parallel segmented flow column strategy for the liquid chromatography-tandem mass spectrometry analysis of organic contaminants in water
Authors: Soliven Arianne , Pareja Lucia , Shalliker R. Andrew , Heinzen Horacio , Pérez-Parada Andrés
Published: December 2019

This study highlights the development of a high peak capacity, high-throughput (HTP) approach for a target list of 62 organic contaminants in an environmental river water matrix on a HPLC conventional 400 bar system.
A Mn:ZnSe quantum dot-based turn-on fluorescent sensor for the highly selective and sensitive detection of Cd2+
Authors: Zhou Zhi-Qiang , Yang Li-Yun , Liao Yuan-Ping , Wu Hui-Yan , Zhou Xiao-Hui , Huang Shan , Liu Yi , Xiao Qi
Published: December 2019

A highly selective and sensitive nanoprobe with fluorescence turn-on sensing properties for recognizing Cd2+ was developed through replacing Mn2+ near the surface of Mn:ZnSe quantum dots.
Patterning of polyoxometalate rings on gold nanorods
Authors: Yang Chenggong , Tao Xingfu , Yang Yang , Liu Kun
Published: December 2019

Polyoxometalates (POMs) were self-assembled on cetyltriethylammonium bromide-covered gold nanorods and formed periodic POM rings, which could be used as templates for the synthesis of Ag nano-rings.
Highly active metal-free peroxidase mimics based on oxygen-doped carbon nitride by promoting electron transfer capacity
Authors: Zhu Weiran , Hao Nan , Lu Jinwen , Dai Zhen , Qian Jing , Yang Xiaodi , Wang Kun
Published: December 2019

A heteroatom oxygen doping strategy was developed to prepare oxygen-doped carbon nitride (OCN). The peroxidase-like activity was greatly improved due to the promoted electron transferability.
N-Heterocyclic carbene/photo-cocatalyzed oxidative Smiles rearrangement: synthesis of aryl salicylates from O-aryl salicylaldehydes
Authors: Xia Zi-Hao , Dai Lei , Gao Zhong-Hua , Ye Song
Published: December 2019

The N-heterocyclic carbene/photo-cocatalyzed oxidative Smiles rearrangement of O-aryl salicylaldehydes was developed, giving the corresponding aryl salicylates in good yields.
The formation mechanism of hexagonal Mo2C defects in CVD graphene grown on liquid copper
Authors: Saeed Maryam , Robson Joseph D. , Kinloch Ian A. , Derby Brian , Liao Chun-Da , Al-Awadhi Sami , Al-Nasrallah Eissa
Published: December 2019

Engineered defects in CVD graphene films are a challenge, and the growth of molybdenum carbide (Mo2C) with CVD graphene can hold great potential. The formation mechanism of Mo2C in CVD graphene is proposed.
Deeply coloured and highly fluorescent dipolar merocyanines based on tricyanofuran
Authors: Derevyanko Nadezhda A. , Ishchenko Alexander A. , Kulinich Andrii V.
Published: December 2019

TCF as the acceptor group of merocyanines, having its own extended π-system, gives access to deeply coloured dyes exhibiting good fluorescence efficiency in the red and near-IR spectral range.
Unusual behaviour of the spin–spin coupling constant 1JCH upon formation of CH⋯X hydrogen bond
Authors: Tupikina Elena Yu. , Denisov Gleb S. , Antonov Alexander S. , Tolstoy Peter M.
Published: December 2019

One-bond coupling constants 1JXY are usually used as a measure of the corresponding X⋯Y interatomic distances.
DFT study of trialkylborohydride-catalysed hydrosilylation of alkenes – the mechanism and its implications
Authors: Nowicki Mateusz , Zaranek Maciej , Pawluć Piotr , Hoffmann Marcin
Published: December 2019

A detailed DFT study reveals the mechanism of trialkylborohydride-catalysed Markovnikov hydrosilylation of aromatic alkenes.
M(H2O)(PO3C10H6OH)·(H2O)0.5 (M = Co, Mn, Zn, Cu): a new series of layered metallophosphonate compounds obtained from 6-hydroxy-2-naphthylphosphonic acid
Authors: Beaubras Félicien , Rueff Jean-Michel , Perez Olivier , Veillon Fabien , Caignaert Vincent , Lohier Jean-François , Cardin Julien , Rogez Guillaume , Jestin Charlotte , Couthon Hélène , Jaffrès Paul-Alain
Published: December 2019

Layered metallophosphonates featuring phenol functions were obtained as single crystal and polycrystalline powders. Thermal stability, magnetic and luminescence properties are reported.
Dynamic responses of community structure and microbial functions of periphytic biofilms during chronic exposure to TiO2 NPs
Authors: Hou Jun , Li Tengfei , Miao Lingzhan , You Guoxiang , Xu Yi , Liu Songqi
Published: December 2019

We investigated the dynamic response of community structure and microbial function of periphytic biofilms during long-term exposure to TiO2 NPs.
Lateral size dependent colloidal stability of graphene oxide in water: impacts of protein properties and water chemistry
Authors: Sun Binbin , Zhang Yinqing , Liu Qing , Yan Chaorui , Xiao Bowen , Yang Jing , Liu Menglin , Zhu Lingyan
Published: December 2019

Whether the stability of GO was related to lateral size depended on the protein type and concentration and solution chemistry conditions.
Catalyst-free vitrimer elastomers based on a dimer acid: robust mechanical performance, adaptability and hydrothermal recyclability
Authors: Li Yingyi , Liu Tuan , Zhang Shuai , Shao Lin , Fei Mingen , Yu Hui , Zhang Jinwen
Published: December 2019

This work introduces a feasible method for the preparation of catalyst-free vegetable oil based vitrimer elastomers with excellent mechanical and recycling properties.
Deformability-induced lift force in spiral microchannels for cell separation
Authors: Guzniczak Ewa , Otto Oliver , Whyte Graeme , Willoughby Nicholas , Jimenez Melanie , Bridle Helen
Published: December 2019

We introduce a novel combination of deformability-induced lift force (FD) and secondary Dean flow in spiral microchannel translated into a label-free purification approach applicable to mammalian cells, processing of millions of cells per min, up to high purities and recovery.
How does evolution design functional free energy landscapes of proteins? A case study on the emergence of regulation in the Cyclin Dependent Kinase family
Authors: Shamsi Zahra , Shukla Diwakar
Published: December 2019

Evolution has altered the free energy landscapes of protein kinases to introduce different regulatory switches and regulate their catalytic activity.
Effect of polymer–nanoparticle interactions on solvent-driven infiltration of polymer (SIP) into nanoparticle packings: a molecular dynamics study
Authors: Venkatesh R. Bharath , Zhang Tianren , Manohar Neha , Stebe Kathleen J. , Riggleman Robert A. , Lee Daeyeon
Published: December 2019

Dynamics of polymer motion into solvent-filled interstices of nanoparticle packings can be controlled by tuning the polymer–nanoparticle interactions, whose effect on the rate of infiltration is non-monotonic as shown by MD simulations.
Probing the frictional properties of soft materials at the nanoscale
Authors: Liamas Evangelos , Connell Simon D. , Ramakrishna Shivaprakash N. , Sarkar Anwesha
Published: December 2019

A knowledge gap exists in understanding nanoscale friction in soft–soft contacts with modulus <100 MPa, relevant to most biological interfaces.
Tunable morphologies and emission of photosensitive supramolecular self-assemblies through positional andtrans–cisisomerization
Authors: Ding Zeyang , Zhang Yuping , Gao Yu , Yang Bing , Jiang Shimei
Published: December 2019

Photo-induced ribbon/fiber-to-sphere transitions together with emission switching based onC3-symmetric cyanostilbene derivatives with different cyano positions.
Size-dependent fluorescence of conjugated polymer dots and correlation with the fluorescence in solution and in the solid phase of the polymer
Authors: Kim Jongho , Lee Jaemin , Lee Taek Seung
Published: December 2019

A size-library of conjugated polymer dots (Pdots) fabricated from a single polymer can be correlated with their emission color. From the correlation, the white-emitting Pdot can be fabricated with the precise control of their size.
Recent progress in synthesis and application of mussel-inspired adhesives
Authors: Guo Qi , Chen Jingsi , Wang Jilei , Zeng Hongbo , Yu Jing
Published: December 2019

This review article gives an overview of the molecular adhesion mechanisms and recent development of mussel inspired functional adhesives.
Stereodivergent routes in organic synthesis: carbohydrates, amino acids, alkaloids and terpenes
Authors: Nájera Carmen , Foubelo Francisco , Sansano José M. , Yus Miguel
Published: December 2019

The natural occurrence of enantiomers and diastereomers is often encountered.
Correction: Preparation of 2-arylquinolines from β-arylpropionitriles with aryllithiums and NIS through iminyl radical-mediated cyclization
Authors: Naruto Hiroki , Togo Hideo
Published: December 2019

Correction for ‘Preparation of 2-arylquinolines from β-arylpropionitriles with aryllithiums and NIS through iminyl radical-mediated cyclization’ by Hiroki Naruto, et al., Org. Biomol. Chem., 2019, 17, 5760–5770.
In situ hydroxyl radical generation using the synergism of the Co–Ni bimetallic centres of a developed nanocatalyst with potent efficiency for degrading toxic water pollutants
Authors: Sharma Rakesh K. , Arora Bhavya , Sharma Shivani , Dutta Sriparna , Sharma Aditi , Yadav Sneha , Solanki Kanika
Published: December 2019

A novel and sustainable bimetallic nanocatalyst has been developed and utilized for the efficient oxidative degradation of water pollutants (2,4-D and MO) under ambient reaction conditions.
Controlled release of basic fibroblast growth factor from a water-floatable polyethylene nonwoven fabric sheet for maintenance culture of iPSCs
Authors: Oyane Ayako , Araki Hiroko , Nakamura Maki , Aiki Yasuhiko , Higuchi Kumiko , Pyatenko Alexander , Adachi Masaki , Ito Yuzuru
Published: December 2019

We created a bFGF-releasing water-floatable nonwoven fabric sheet via simple bFGF adsorption following oxygen plasma treatment, and demonstrated its potential as a new bFGF supplement for culture media of stem cells.
Flexible pH sensor based on a conductive PANI membrane for pH monitoring
Authors: Li Yongqian , Mao Yunlong , Xiao Chi , Xu Xiaoli , Li Xueyong
Published: December 2019

A conductimetric flexible film pH sensor working in sensing materials of PANI membrane was developed for clinic wound monitoring.
In situ synthesis of CdS/CdWO4 nanorods core–shell composite via acid dissolution
Authors: Nagakawa Haruki , Nagata Morio
Published: December 2019

The prevention of photocorrosion in photocatalysts allows for the use of a wide variety of visible-light-responsive photocatalysts, leading to highly efficient photocatalytic reactions.
Transitions between representational levels: characterization of organic chemistry students’ mechanistic features when reasoning about laboratory work-up procedures
Authors: Keiner Liz , Graulich Nicole
Published: December 2019

Chemists refer to chemical phenomena on different representational levels—macroscopic, symbolic, and submicroscopic—which are directly related and connected to each other. Especially in the laboratory, students have to reason about various mechanistic features at the submicroscopic level and connect them in a meaningful way to make sense of the observable. There is plenty of evidence in chemistry education that students have difficulty connecting the different representational levels when thinking about chemical phenomena. However, current literature provides limited information about the mechanistic features that students activate when reasoning about phenomena and how they transition between the representational levels when in an organic chemistry laboratory. In this study, we performed in-depth analysis of how organic chemistry student teachers (N = 9) explained typical work-up procedures and characterized their activated mechanistic features and transitions between the different representational levels. Our analysis revealed that the students do not activate all features of a mechanism in the same way and construct various explanatory approaches. The findings emphasize the need to explicitly communicate how to connect the macroscopic and submicroscopic levels in a meaningful way in the laboratory. The implications of these findings for research, teaching, and learning to foster meaningful activation of mechanistic features are discussed.
Silica-supported, narrowly distributed, subnanometric Pt–Zn particles from single sites with high propane dehydrogenation performance
Authors: Rochlitz Lukas , Searles Keith , Alfke Jan , Zemlyanov Dmitry , Safonova Olga V. , Copéret Christophe
Published: December 2019

Silica-supported subnanometric PtZn particles, prepared via surface organometallic chemistry, are highly productive and selective for propane dehydrogenation.
Oscillations of a cantilevered micro beam driven by a viscoelastic flow instability
Authors: Dey Anita A. , Modarres-Sadeghi Yahya , Lindner Anke , Rothstein Jonathan P.
Published: December 2019

We report evidence of viscoelastic fluid–structure interactions at micro-scale between a flexible cantilevered beam and a confined flow of polymer solution.
The importance of the Mg–Mg interaction in Mg3Sb2–Mg3Bi2 shown through cation site alloying
Authors: Wood Max , Imasato Kazuki , Anand Shashwat , Yang Jiong , Snyder G. Jeffrey
Published: December 2019

Herein we study the effect alloying Yb onto the octahedral cite of Te doped Mg3Sb1.5Bi0.5 has and show that the reduction in mobility can be explained with an alloy scattering argument due to disrupting the Mgoctahedral–Mgtetrahedral interaction.
A CO2 adsorption dominated carbon defect-based electrocatalyst for efficient carbon dioxide reduction
Authors: Wu Qilong , Gao Jin , Feng Jianrui , Liu Qian , Zhou Yunjie , Zhang Shengbo , Nie Manxiu , Liu Yang , Zhao Jiongpeng , Liu Fuchen , Zhong Jun , Kang Zhenhui
Published: December 2019

A defect-derived metal-free electrocatalyst with appropriate CO2 adsorption for efficient carbon dioxide reduction.
The facile soft-template-morphology-controlled (STMC) synthesis of ZnIn2S4 nanostructures and their excellent morphology-dependent adsorption properties
Authors: Khan Afaq Ahmad , Chowdhury Arif , Kumari Sunita , Hussain Sahid
Published: December 2019

ZnIn2S4 nanostructures were fabricated with controlled morphology and utilized for the adsorption of an organic dye and toxic metal ions.
Correction: In pursuit of catalytic cathodes for lithium–oxygen batteries
Authors: Eftekhari Ali , Ramanujam Balaji
Published: December 2019

Correction for ‘In pursuit of catalytic cathodes for lithium–oxygen batteries’ by Ali Eftekhari et al., J. Mater. Chem. A, 2017, 5, 7710–7731.
Magnifying effect of weak grid connection for a PMSG to induce torsional sub‐synchronous oscillations under the condition of open‐loop modal resonance
Authors: Du Wenjuan , Wang Yang , Wang Xubin , Wang Haifeng
Published: December 2019

When open‐loop modal resonance (OLMR) happens, a grid‐connected PMSG may induce torsional sub‐synchronous oscillations (SSOs) in a power system. This study examines the magnifying effect of a weak grid connection for the PMSG to induce torsional SSOs under the condition of OLMR. Theoretical analysis is carried out in this study to indicate that the weak grid connection magnifies the impact of OLMR, when the resonant mode of PMSG is dominated by the dynamics of a phase‐locked loop (PLL) or the DC voltage control of the grid side converter. The magnifying effect of weak grid connection is analytically proved to have two aspects. First, the magnitude of the real part of the open‐loop residue of the PMSG increases when the grid connection weakens. Second, the magnitude of the real part of the resonant open‐loop oscillation mode of PMSG decreases under the condition of weak grid connection. According to the OLMR theory, the weakly connected PMSG is more likely to cause growing torsional SSOs when the grid connection is weak. This study helps to understand the mechanism of recent SSO incidents in a practical Chinese power system is analysed. Study cases are presented to demonstrate and evaluate the analysis and conclusions made in this study.
Energy router for SC: GC, SA and transition mode controls
Authors: Vilhena Nuno , Roncero‐Clemente Carlos , Delgado‐Gomes Vasco , Fernão Pires Vitor , Martins João F.
Published: December 2019

From the electrical point of view, the concept of smart community (SC) was defined as a distributed system consisting of a set of smart homes, distributed energy resources (DERs) and energy storage systems (ESSs) using SC controllers to enable smart power management. In this context, the SC energy management system (SCEMS) acts as aggregator of these resources, aiming to assure benefits for every SC stakeholder by setting the SC operation. The references given by the SCEMS must be accurately tracked by the energy routers (ERs), intended as one of the key components of the SC, acting as smart interface between the utility grid and the prosumers’ DER and ESS. This study proposes a flexible, robust and simple control strategy for a single‐phase ER. The ER regulates the active and reactive powers in grid‐connected (GC) mode, and the voltage and frequency when operating in stand‐alone (SA) mode. A seamless transition between SA and GC is demonstrated, avoiding undesired transients. The design and implementation of the proposed control strategy is progressively explained. Finally, this is tested via simulation (in PSCAD/EMTDC software) and verified with the experimental prototype.
Introduction to Laguerre‐based stochastic economic predictive functional control for optimal real‐time power dispatch under uncertainty
Authors: Ramandi Mostafa Yousefi , Bigdeli Nooshin , Afshar Karim
Published: December 2019

This study presents a Laguerre‐based stochastic economic predictive functional control (L‐SEPFC) method for real‐time power dispatch of balance responsible parties (BRPs). In this regard, at the control layer, an L‐SEPFC method operates on the energy time scale and optimises the expected economic performance of the BRP. Calculated set points in this layer are average power injection of controllable generators, as well as known disturbance of prediction wind generation. The novel L‐SEPFC scheme is able to cope with the wind uncertainty occurring in the real‐time operation of BRPs. Furthermore, the proposed algorithm is able to take into account the technical constraints of generators and transmission line constraints of the power network. Due to the parameterisation of the future control signal based on the Laguerre function, the proposed method is faster than the nominal predictive algorithms. Simulations on an IEEE 118‐bus test system with proposed method shows improvements inability to track reference production, economic performance, imbalance energy and computational burden with respect to nominal predictive controllers.
L’autisme en France, début 2019
Authors: Wacjman Claude
Published: December 2019

Les lignes qui suivent sont basées sur le recueil des données écrites recueillies entre le mois de janvier et le mois de mai 2019. Elles reflètent les intérêts professionnels de l’auteur, ce qui les fait apparaître biaisées, à juste titre. Cette compilation se situe après de nombreux travaux dont : « La fabrication de l’”autiste handicapé” : chronique d’un passage à l’acte », [avec Olivier Douville], Psychologie clinique, no 2, 1996, p. 105-134, repris dans Figures de la psychanalyse. Logos-Anankè, no 24, 2012/2, p. 99-129; Travailler avec des enfants malades mentaux, Paris, Dunod, 1997; « Que nous enseigne la controverse sur l’autisme ? », Psychologie Clinique, no 36, 2013/2; « Enfants anormaux, inadaptés, handicapés : une continuité idéologique ? », Vie Sociale, 4/2013; Clinique institutionnelle des troubles psychiques. Des enfants autistes à ceux des ITEP, Toulouse, Èrès, 2013, p. 9-100; « L’autisme depuis 2012, année grande cause nationale », Psychologie Clinique, no 38, 2014/2, p. 8-29; « Vers une police de l’autisme (2013-2014) », Psychologie Clinique, no 39, 2015/1, p. 7-24; Le grand imbroglio de l’autisme, Nîmes, Champ social éditions, 2018.
Troubles bipolaires et pertinence du sexuel infantile
Authors: Morice Wilfried
Published: December 2019

La conception des variations de l’humeur, des renversements des affects en terme de bipolarité procéderait-elle de la résistance individuelle et collective à ce que, à la suite de Freud, on nomme le sexuel infantile ? Se spécifiant athéorique la notion de « trouble bipolaire » promeut pourtant intrinsèquement un idéal de constance et de pérennité qui donne à entendre la dénégation des questions relatives à la perte de l’objet et son traitement par la psyché. Considérant avec J. Laplanche que la pensée psychanalytique progresse, entre autre, par banalisations et réaffirmations, l’auteur explore ce que la logique bipolaire implique de résistance aux désirs d’inceste et de meurtre aux origines de la pensée. La notion de sexuel infantile est ainsi précisée et replacée dans l’évolution de la connaissance psychanalytique et ses propres mouvements de refoulement. Un retour sur la métapsychologie freudienne relative aux problématiques de perte objectale permet d’attester son statut foncier. L’incidence du narcissisme et du masochisme, ainsi qu’une hypothèse sur l’implication d’une dimension incestueuse dans les situations mélancoliques sont envisagées. Distants de quelques années, deux temps de la cure d’une patiente qui répondrait aux critères diagnostics des « troubles bipolaires », viennent témoigner de la mobilisation possible du lien mélancolique à l’objet perdu.
Le numérique : du symbolique désaffecté
Authors: Decan Philippe
Published: December 2019

Ce que l’on nomme aujourd’hui le numérique, l’intelligence artificielle et la robotique, ont pris son essor après la seconde guerre mondiale sous le nom de cybernétique. Longtemps en gestation, ce nouvel aspect du discours de la science et de l’agir technologique qui lui est inféodé a débouché, produit depuis une trentaine d’années des développements économiques sans précédent plaçant les entreprises dominantes de ce domaine aux premiers rangs des bourses mondiales. Ce bouleversement majeur conduit à de multiples applications qui ont transformé nos vies quotidiennes dans leurs aspects pratiques mais aussi affectifs et intellectuels. À partir d’une relecture de la conférence de Jacques Lacan « Le symbolique, l’imaginaire et le réel » de 1953, je propose de développer plusieurs considérations relatives à l’influence du surgissement numérique sur nos affects et notre appareil psychique. Les changements contemporains de notre rapport au réel, à l’imaginaire et au symbolique, liés à l’évolution technologique seront également explorés, ainsi que l’efficience du numérique sur le Réel. Enfin, la notion de symbolique désaffecté sera avancée pour aider à conceptualiser l’influence de l’évolution technologique actuelle sur nos fonctionnements psychiques.
Eisentherapie bei Dialysepatienten
Authors: Janssen Ulf
Published: December 2019

Dialysepatienten entwickeln sowohl einen absoluten als auch funktionellen Eisenmangel. Dabei spielen Hepcidinspiegel, die durch Inflammation und eine verminderte renale Clearance erhöht sind, eine zentrale Rolle. Diese führen zu einer Hemmung der enteralen Eisenresorption und der Eisenfreisetzung aus dem retikuloendothelialen System (RES). Bei Hämodialysepatienten treten verfahrensbedingte Eisenverluste hinzu. Im Gegensatz zu Peritonealdialysepatienten ist eine orale Eisentherapie bei Hämodialysepatienten i. d. R. nicht effektiv und eine intravenöse (i. v.) Gabe erforderlich. Dafür stehen dextranbasierte und dextranfreie Eisen(III)-Zucker-Komplexe zur Verfügung, die sich hinsichtlich der maximal applizierbaren Menge und der Häufigkeit von Nebenwirkungen unterscheiden. Vorteilen einer i. v. Eisentherapie wie einer Reduktion der Dosis Erythropoese stimulierender Agenzien (ESA) und von Bluttransfusionen stehen potenzielle Risiken wie Überempfindlichkeitsreaktionen, eine Eisenüberladung, oxidativer Stress und Infektionen gegenüber. Während die KDIGO-Leitlinien aus dem Jahre 2012 eine Eisentherapie bei einer Transferrinsättigung (TSAT) von maximal 30 % und einem Serum-Ferritin von unter 500 ng/ml empfehlen, haben sich in vielen Zentren in der klinischen Praxis die angestrebten oberen Ferritingrenzwerte nach oben verschoben. Aktuelle Daten der PIVOTAL-Studie zeigen, dass eine proaktive hochdosierte Eisentherapie á 400 mg i. v. pro Monat bei einer TSAT von unter 40 % und einem Serum-Ferritin von maximal 700 ng/ml klinische Endpunkte wie die Mortalität und kardiovaskuläre Ereignisse reduziert, ohne zu einer Zunahme von Infektionen zu führen.
Psychosomatik in der Kinderneurologie
Authors: Merkenschlager Andreas , Bernhard Matthias K. , Hiemisch Andreas , Nickel Petra
Published: December 2019

Basierend auf dem bio-psycho-sozialen Modell von Krankheit und Gesundheit beschäftigt sich die Neuropädiatrie mit dissoziativen und somatoformen Störungen des Kindes- und Jugendalters. Besonders die sog. Konversionsstörungen führen zu einer häufigen Inanspruchnahme des Kinderneurologen. Die nicht willentlich erzeugte Symptomatik basiert nicht auf einer identifizierbaren organischen Ursache und ist inkompatibel mit anatomischen und physiologischen Gesetzmäßigkeiten oder bekannten neurologischen Erkrankungen. Sie bedeuten für den Patienten und seine Familie eine erhebliche psychoemotionale Belastung und Funktionseinschränkung. Die Störungsbilder bergen das Risiko unnötiger und belastender Diagnostik und – mitunter invasiver – Therapie. Die Prognose psychotherapeutischer Interventionen ist umso günstiger je kürzer das Zeitintervall zwischen Manifestation und Diagnosestellung ist.
Perspektive eines PrEP-Beraters auf die PrEP
Authors: Kayser Arne
Published: December 2019

Arne Kayser arbeitet als Sexualberater bei der Aidshilfe Bochum am WIR-Zentrum Bochum. Im Szene-Jargon zuweilen liebevoll-ironisch als „PrEP-Mutti von Bochum“ tituliert, hat er bislang knapp 200 PrEP-Nutzende begleitet und hat eine spezielle PrEP-Sprechstunde – die PrEPstunde – entwickelt, die sich großer Beliebtheit erfreut.
„Verletzungen hinterlassen Stressspuren“ – Gisamone Grunwald über LIMBIC TOUCH®
Authors: Grunwald Gisamone
Published: December 2019

Sportler erreichen nicht das alte Niveau, Patienten haben nach einer TEP Angst vor Bewegung. Gisamone Grunwald ist überzeugt: Die Methode Limbic Touch unterstützt Patienten darin, Stressspuren nach einem Trauma zu verarbeiten und dem Körper wieder mehr zu vertrauen. Stephanie Moers sprach mit ihr über die Methode und die Ausbildung, die Grunwald jetzt explizit auch für Physiotherapeuten anbietet.
Gastrosplenic Fistula without Malignancy Management in a 16-Year-Old Boy
Authors: Malik Aila , Onwubiko Chinwendu , Chen Mike , Radulescu Andrei , Galloway David , Martin Colin
Published: December 2019

Gastrosplenic fistula is a very rare entity, most commonly occurring as a distinctive complication of splenic or gastric malignancies, most notably diffuse large B cell lymphoma (DLBCL). Benign gastric ulcer, splenic abscess, and Crohn's disease have also been reported as possible causes. We report a nonmalignant case of 16-year–old male with a gastrosplenic fistula of unclear etiology. The fistulous tract was confirmed by an upper endoscopy and an upper gastrointestinal series. Subsequently, it was surgically managed with a subtotal gastrectomy with “Roux-en-Y” reconstruction and a feeding jejunostomy.
Modeling a Clinical Pathway for Contraception
Authors: Sooter Letha J. , Hasley Steve , Lario Robert , Rubin Kenneth S. , Hasić Faruk
Published: December 2019

Background The Centers for Disease Control and Prevention (CDC) produced a 72-page document titled “U.S. Selective Practice Recommendations for Contraceptive Use” in 2016. This document contains the medical eligibility criteria (MEC) for contraceptive initiation or continuation based on a patient's current health status. Notations such as Business Process Model and Notation (BPMN) and Decision Model and Notation (DMN) might be useful to model such recommendations.

Objective Our objective was to use BPMN and DMN to model and standardize the processes and decisions involved in initiating birth control according to the CDC's MEC for birth control initiation. This model could then be incorporated into an electronic health records system or other digital platform.

Methods Medical terminology, processes, and decisions were modeled in coordination with the CDC to ensure correctness. Challenges in terminology bindings were identified and categorized.

Results A model was successfully produced. Integration of clearly defined data elements proved to be the biggest challenge.

Conclusion BPMN and DMN have strengths and weaknesses when modeling medical processes; however, they can be used to successfully create models for clinical pathways.
Faster Detection of Ischemia in Free Muscle Transfer When Using Microdialysis
Authors: Rauff-Mortensen Andreas , Berggren-Olsen Mette Marie , Kirkegaard Hans , Houlind Kim , Birke-Sørensen Hanne
Published: December 2019

Background Microdialysis is a clinical method used to detect ischemia after microvascular surgery. Microdialysis is easy to use and reliable, but its value in most clinical settings is hampered by a 1- to 2-h delay in the delivery of patient data. This study evaluated the effectiveness of an increase in the microdialysis perfusion rate from 0.3 to 1.0 µL/min on the diagnostic delay in the detection of ischemia.

Methods In eight pigs, two symmetric pure muscle transfers were dissected based on one vascular pedicle each. In each muscle, two microdialysis catheters were placed. The two microdialysis catheters were randomized to a perfusion rate of 0.3 or 1.0 µL/min, and the two muscle transfers were randomized to arterial or venous ischemia, respectively. After baseline monitoring, arterial and venous ischemia was introduced by the application of vessel clamps. Microdialysis sampling was performed throughout the experiment. The ischemic cutoff values were based on clinical experience set as follows: CGlucose < 0.2 mmol/L, CLactate > 7 mmol/L, and the lactate/pyruvate ratio > 50.

Results The delay for the detection of 50% of arterial ischemia was reduced from 60 to 25 minutes, and for the detection of all cases of arterial ischemia, the delay was reduced from 75 to 40 minutes when the perfusion rate was increased from 0.3 to 1.0 µL/min. After the same increase in perfusion, the detection of 50% of venous ischemia was reduced from 75 to 40 minutes, and for all cases of venous ischemia, a reduction from 135 to 95 minutes was found.

Conclusion When using microdialysis for the detection of ischemia in pure muscle transfers, an increase in the perfusion rate from 0.3 to 1.0 µL/min can reduce the detection delay of ischemia.
Effectiveness of dry needling in equinovarus foot deformity in patients with cerebrovascular accident
Authors: Z. Sánchez Milá , C. López Pascua , E. Ranz Ramírez , A. Castrillo Calvillo
Published: December 2019

Introduction Spasticity secondary to cerebrovascular accident is one of the main causes of disability in adults. Equinovarus foot is a common condition in patients with cerebrovascular accident, with an estimated prevalence of 18% (Verdié C. 2004). This deformity is mainly caused by spasticity of the tibialis posterior muscle, together with weakness of the tibialis anterior.

Aims To determine the effects of deep dry needling together with neurorehabilitation treatment (based on the Bobath concept) on spasticity and motor function after a cerebrovascular accident.

Material and Methods A single-blinded randomized experimental study, which comprised ten (n = 10) patients who had suffered a cerebrovascular accident, who were randomly assigned to a control group (CG) who received neurorehabilitation treatment (n = 5) and another experimental group (EG) who received ultrasound-guided dry needling in the tibialis posterior and tibialis anterior muscles plus neurorehabilitation treatment (n = 5). Measurements were made at baseline and ten minutes after treatment by a blinded evaluator who measured spasticity (Ashworth scale) and motor function (timed up and go test).

Results The subjects who received dry needling showed a decrease in spasticity after treatment of the tibialis posterior (P < 0.001) and the tibialis anterior muscles (P < 0.003) compared to those who did not receive treatment. The descriptive analysis of the timed up and go test, (CG pre:22.7720/post:21.8060 and EG pre:23.8960/post:17.9780*) revealed a decrease in times for both groups, which was more significant in the group of neurorehabilitation treatment plus dry needling.

Conclusion The inclusion of deep dry needling in a session of neurorehabilitation treatment (following the Bobath concept) appears to be effective for the normalization of tone and for the improvement of balance during the gait cycle in patients who have suffered a cerebrovascular accident.
Dry needling in situations with varying degrees of muscle tone: an ex vivo study
Authors: R. Margalef , M. Bosque , MM Santafé
Published: December 2019

Introduction Numerous studies support the fact that myofascial trigger points are responsible for the clinical findings in myofascial pain syndrome, therefore it is reasonable to believe that the destruction of the same via dry needling may be an optimal solution. However, this technique has not been assessed in relation to muscle tone.

Methods The experiments were performed with the levator auris longus (LAL) muscle of Swiss adult mice. The muscles, once extracted from the animal, were maintained ex vivo using normal oxygenated Ringer solution. Once these were extracted, they were extended upon a Sylgard® surface, maintained in vivo at all times. In these conditions, 15 insertions were performed with dry needling needles (0.25 mm X 25mm; AguPunt) in the attempt to avoid repeating needling on the same site. Different degrees of muscle tone were obtained as follows (from lesser to greater tone): healthy animals; animal model of myofascial trigger points (PGM); muscles which, once extracted were treated with ClK 30 mM and ClCa2 5mM; formaldehyde. Immediately after treatment, the muscles were dyed with methylene blue.

Results The muscle fibers of healthy muscles are mostly pushed aside by the needle, practically without injury. Muscles with MTrPs are more injured than healthy muscles because of the use of dry needling, albeit only partially. The tone acquired with ClK and ClCa2 is more powerful and generalized, therefore, dry needling creates a greater injury. Lastly, formaldehyde provokes a powerful increase of muscle tension, however the injury produced by dry needling is not so noteworthy, due to the fact that the muscle fibers fixed with formaldehyde are extremely resistant.

Conclusions Dry needling is a technique which, overall, provokes limited lesions, independent of the muscle tone.
Energy decomposition analysis based on broken symmetry unrestricted density functional theory
Authors: Tang Zhen , Jiang Zhen , Chen Hongjiang , Su Peifeng , Wu Wei
Published: December 2019

In this paper, the generalized Kohn-Sham energy decomposition analysis (GKS-EDA) scheme is extended to molecular interactions in open shell singlet states, which is a challenge for many popular EDA methods due to the multireference character. Based on broken symmetry (BS) unrestricted density functional theory with a spin projection approximation, the extension scheme, named GKS-EDA(BS) in this paper, divides the total interaction energy into electrostatic, exchange-repulsion, polarization, correlation, and dispersion terms. Test examples include the pancake bond in the phenalenyl dimer, the ligand interactions in the Fe(ii)-porphyrin complexes, and the radical interactions in dehydrogenated guanine-cytosine base pairs and show that GKS-EDA(BS) is a practical EDA tool for open shell singlet systems.
Positive, negative, and sign-changing solutions to a quasilinear Schrödinger equation with a parameter
Authors: Yang Xianyong , Tang Xianhua , Zhang Youpei
Published: December 2019

In this paper, we study the following quasilinear Schrödinger equation with a parameter: −Δu+V(x)u−καΔ(|u|2α)|u|2α−2u=|u|p−2u+|u|(2α)2*−2u  in  RN, where N ≥ 3, α>12, 2 < p < (2α)2*, and κ is a positive constant. Under different assumptions on V, we obtain the existence of positive, negative, and sign-changing solutions. Our results generalize the results of Liu et al. [J. Differ. Equations 187, 473–493 (2003)] into the critical case for general α.
Apparatus for electrically detected electron nuclear double resonance in solid state electronic devices
Authors: Manning Brian R. , Waskiewicz Ryan J. , McCrory Duane J. , Lenahan Patrick M.
Published: December 2019

We have developed a sensitive electron nuclear double resonance spectrometer in which the detection takes place through electrically detected magnetic resonance. We demonstrate that the spectrometer can provide reasonably high signal to noise spectra of 14N interactions with deep level centers in a fully processed bipolar junction transistor at room temperature.
Coherent acoustic phonon dynamics in chiral copolymers
Authors: Scholz Mirko , Morgenroth Marius , Cho Min Ju , Choi Dong Hoon , Lenzer Thomas , Oum Kawon
Published: December 2019

Coherent phonon oscillations in the UV-Vis transient absorption and circular dichroism response of two chiral polyfluorene-based copolymer thin films are investigated. A slow oscillation in the hundred picosecond regime indicates the propagation of a longitudinal acoustic phonon with a frequency in the gigahertz range through cholesteric films of PFPh and PFBT, which allow for the optical determination of the longitudinal sound velocity in these polymers, with values of (2550 ± 140) and (2490 ± 150) m s−1, respectively. The oscillation is induced by a strain wave, resulting in a pressure-induced periodic shift of the electronic absorption bands, as extracted from a Fourier analysis of the transient spectra. The acoustic phonon oscillation is also clearly detected in the transient circular dichroism (TrCD) response of PFPh, indicating a transient pressure-induced shift of the CD spectrum and possibly also phonon-induced chirality changes via pitch length modulation of the cholesteric helical polymer stack.
A uniform flow–cavity ring-down spectrometer (UF-CRDS): A new setup for spectroscopy and kinetics at low temperature
Authors: Suas-David N. , Thawoos S. , Suits A. G.
Published: December 2019

The UF-CRDS (Uniform Flow–Cavity Ring Down Spectrometer) is a new setup coupling for the first time a pulsed uniform (Laval) flow with a continuous wave CRDS in the near infrared for spectroscopy and kinetics at low temperature. This high resolution and sensitive absorption spectrometer opens a new window into the phenomena occurring within UFs. The approach extends the detection range to new electronic and rovibrational transitions within Laval flows and offers the possibility to probe numerous species which have not been investigated yet. This new tool has been designed to probe radicals and reaction intermediates but also to follow the chemistry of hydrocarbon chains and PAHs which play a crucial role in the evolution of astrophysical environments. For kinetics measurements, the UF-CRDS combines the CRESU technique (French acronym meaning reaction kinetics in uniform supersonic flows) with the SKaR (Simultaneous Kinetics and Ring-Down) approach where, as indicated by its name, the entire reaction is monitored during each intensity decay within the high finesse cavity. The setup and the approach are demonstrated with the study of the reaction between CN (v = 1) and propene at low temperature. The recorded data are finally consistent with a previous study of the same reaction for CN (v = 0) relying on the CRESU technique with laser induced fluorescence detection.