bluuebunny/crossref_metadata_2025 huggingface dataset:
Using a polygenic score in a family design to understand genetic influences on musicality
Authors: Wesseldijk Laura W. , Abdellaoui Abdel , Gordon Reyna L. ,   23andMe Research Team, Aslibekyan Stella , Auton Adam , Babalola Elizabeth , Bell Robert K. , Bielenberg Jessica , Bryc Katarzyna , Bullis Emily , Coker Daniella , Partida Gabriel Cuellar , Dhamija Devika , Das Sayantan , Elson Sarah L. , Filshtein Teresa , Fletez-Brant Kipper , Fontanillas Pierre , Freyman Will , Faaborg Anna , Fuller Shirin T. , Gandhi Pooja M. , Heilbron Karl , Hicks Barry , Jewett Ethan M. , Kukar Katelyn , Lin Keng-Han , Lowe Maya , McCreight Jey C. , McIntyre Matthew H. , Micheletti Steven J. , Moreno Meghan E. , Mountain Joanna L. , Nandakumar Priyanka , Noblin Elizabeth S. , O’Connell Jared , Huang Yunru , Petrakovitz Aaron A. , Lane Vanessa , Petrakovitz Aaron , Kim Joanne S. , Poznik G. David , Schumacher Morgan , Shastri Anjali J. , Shelton Janie F. , Shi Jingchunzi , Shringarpure Suyash , Tran Vinh , Tung Joyce Y. , Wang Xin , Wang Wei , Weldon Catherine H. , Wilton Peter , Hernandez Alejandro , Wong Corinna , Tchakouté Christophe Toukam , Ullén Fredrik , Mosing Miriam A.
Published: August 2022

To further our understanding of the genetics of musicality, we explored associations between a polygenic score for self-reported beat synchronization ability (PGSrhythm) and objectively measured rhythm discrimination, as well as other validated music skills and music-related traits. Using family data, we were able to further explore potential pathways of direct genetic, indirect genetic (through passive gene–environment correlation) and confounding effects (such as population structure and assortative mating). In 5648 Swedish twins, we found PGSrhythm to predict not only rhythm discrimination, but also melody and pitch discrimination (betas between 0.11 and 0.16, p < 0.001), as well as other music-related outcomes (p < 0.05). In contrast, PGSrhythm was not associated with control phenotypes not directly related to music. Associations did not deteriorate within families (N = 243), implying that indirect genetic or confounding effects did not inflate PGSrhythm effects. A correlation (r = 0.05, p < 0.001) between musical enrichment of the family childhood environment and individuals' PGSrhythm, suggests gene–environment correlation. We conclude that the PGSrhythm captures individuals' general genetic musical propensity, affecting musical behavior more likely direct than through indirect or confounding effects.
Mixed convection flow of an electrically conducting viscoelastic fluid past a vertical nonlinearly stretching sheet
Authors: Jafar Ahmad Banji , Shafie Sharidan , Ullah Imran , Safdar Rabia , Jamshed Wasim , Pasha Amjad Ali , Rahman Mustafa Mutiur , Hussain Syed M. , Rehman Aysha , El Din El Sayed M. Tag , Eid Mohamed R.
Published: August 2022

The study of hydromagnetic mixed convection flow of viscoelastic fluid caused by a vertical stretched surface is presented in this paper. According to this theory, the stretching velocity varies as a power function of the displacement from the slot. The conservation of energy equation includes thermal radiation and viscous dissipation to support the mechanical operations of the heat transfer mechanism. Through the use of an adequate and sufficient similarity transformation for a nonlinearly stretching sheet, the boundary layer equations governing the flow issue are converted into a set of ordinary differential equations. The Keller box technique is then used to numerically solve the altered equations. To comprehend the physical circumstances of stretching sheets for variations of the governing parameters, numerical simulations are made. The influence and characteristic behaviours of physical parameters were portrayed graphically for the velocity field and temperature distributions. The research shows that the impact of the applied magnetic parameter is to improve the distribution of the viscoelastic fluid temperature and reduce the temperature gradient at the border. Temperature distribution and the associated thermal layer are shown to have improved because of radiative and viscous dissipation characteristics. Radiation causes additional heat to be produced in liquid, raising the fluid's temperature. It was also found that higher velocities are noticed in viscoelastic fluid as compared with Newtonian fluid (i.e., when K = 0).
Small molecule mediated inhibition of protein cargo recognition by peroxisomal transport receptor PEX5 is toxic to Trypanosoma
Authors: Napolitano Valeria , Softley Charlotte A. , Blat Artur , Kalel Vishal C. , Schorpp Kenji , Siebenmorgen Till , Hadian Kamyar , Erdmann Ralf , Sattler Michael , Popowicz Grzegorz M. , Dubin Grzegorz
Published: August 2022

Trypanosomiases are life-threatening infections of humans and livestock, and novel effective therapeutic approaches are needed. Trypanosoma compartmentalize glycolysis into specialized organelles termed glycosomes. Most of the trypanosomal glycolytic enzymes harbor a peroxisomal targeting signal-1 (PTS1) which is recognized by the soluble receptor PEX5 to facilitate docking and translocation of the cargo into the glycosomal lumen. Given its pivotal role in the glycosomal protein import, the PEX5–PTS1 interaction represents a potential target to inhibit import of glycolytic enzymes and thus kill the parasite. We developed a fluorescence polarization (FP)-based assay for monitoring the PEX5–PTS1 interaction and performed a High Throughput Screening (HTS) campaign to identify small molecule inhibitors of the interaction. Six of the identified hits passed orthogonal selection criteria and were found to inhibit parasite growth in cell culture. Our results validate PEX5 as a target for small molecule inhibitors and provide scaffolds suitable for further pre-clinical development of novel trypanocidal compounds.
Practical counting of substitutive paths on a planar infrastructure network
Authors: Hayashi Yukio , Tanaka Atsushi
Published: August 2022

When there are many non-intersecting paths between two vertices on a network, the connectivity is fault-tolerant. Because of no common vertices on these paths, they can be emergently used in avoiding destroyed parts on the usual paths by any disasters or attacks. It gives a tolerance index whether the combination of non-intersecting paths is many or few. However, to enumerate such paths is an intractable combinatorial problem, no practical algorithm has been known. On the other hand, many socio-technological infrastructure networks are embedded on the surface of Earth. Thus, as an approximate solution, we extendedly apply the counting method based on a path matrix with our proposed mapping to directed acyclic graphs from a planar network according to each pair of source and terminal vertices. The tendency of many or few combinations of the paths is clearly investigated through computer simulations for realistic networks. This approach will be useful for evaluating the existence of substitutive paths to improve the tolerance in risk management.
Semi-supervised classifier guided by discriminator
Authors: Jamroziński Sebastian , Markowska-Kaczmar Urszula
Published: August 2022

Some machine learning applications do not allow for data augmentation or are applied to modalities where the augmentation is difficult to define. Our study aimed to develop a new method in semi-supervised learning (SSL) applicable to various modalities of data (images, sound, text), especially when augmentation is hard or impossible to define, i.e., medical images. Assuming that all samples, labeled and unlabeled, come from the same data distribution, we can say that labeled and unlabeled data sets used in the semi-supervised learning tasks are similar. Based on this observation, the data embeddings created by the classifier should also be similar for both sets. In our method, finding these embeddings is achieved based on two models—classifier and an auxiliary discriminator model, inspired by the Generative Adversarial Network (GAN) learning process. The classifier is trained to build embeddings for labeled and unlabeled datasets to cheat discriminator, which recognizes whether the embedding comes from a labeled or unlabeled dataset. The method was named the DGSSC from Discriminator Guided Semi-Supervised Classifier. The experimental research aimed evaluation of the proposed method on the classification task in combination with the teacher-student approach and comparison with other SSL methods. In most experiments, training the networks with the DGSSC method improves accuracy with the teacher-student approach. It does not deteriorate the accuracy of any experiment.
Tumor spheroids accelerate persistently invading cancer cells
Authors: Audoin Melanie , Søgaard Maria Tangen , Jauffred Liselotte
Published: August 2022

Glioblastoma brain tumors form in the brain’s white matter and remain one of the most lethal cancers despite intensive therapy and surgery. The complex morphology of these tumors includes infiltrative growth and gain of cell motility. Therefore, various brain-mimetic model systems have been developed to investigate invasion dynamics. Despite this, exactly how gradients of cell density, chemical signals and metabolites influence individual cells’ migratory behavior remains elusive. Here we show that the gradient field induced by the spheroid—accelerates cells’ invasion of the extracellular matrix. We show that cells are pushed away from the spheroid along a radial gradient, as predicted by a biased persistent random walk. Thus, our results grasp in a simple model the complex behavior of metastasizing cells. We anticipate that this well-defined and quantitative assay could be instrumental in the development of new anti-cancer strategies.
Spinal degeneration is associated with lumbar multifidus morphology in secondary care patients with low back or leg pain
Authors: Cooley Jeffrey R. , Jensen Tue S. , Kjaer Per , Jacques Angela , Theroux Jean , Hebert Jeffrey J.
Published: August 2022

Associations between multifidus muscle morphology and degenerative pathologies have been implied in patients with non-specific low back pain, but it is unknown how these are influenced by pathology severity, number, or distribution. MRI measures of pure multifidus muscle cross-sectional area (CSA) were acquired from 522 patients presenting with low back and/or leg symptoms in an outpatient clinic. We explored cross-sectional associations between the presence, distribution, and/or severity of lumbar degenerative pathologies (individually and in aggregate) and muscle outcomes in multivariable analyses (beta coefficients [95% CI]). We identified associations between lower pure multifidus muscle CSA and disc degeneration (at two or more levels): − 4.51 [− 6.72; − 2.3], Modic 2 changes: − 4.06 [− 6.09; − 2.04], endplate defects: − 2.74 [− 4.58; − 0.91], facet arthrosis: − 4.02 [− 6.26; − 1.78], disc herniations: − 3.66 [− 5.8; − 1.52], and when > 5 pathologies were present: − 6.77 [− 9.76; − 3.77], with the last supporting a potential dose–response relationship between number of spinal pathologies and multifidus morphology. Our findings could hypothetically indicate that these spinal and muscle findings: (1) are part of the same degenerative process, (2) result from prior injury or other common antecedent events, or (3) have a directional relationship. Future longitudinal studies are needed to further examine the complex nature of these relationships.
Precise heteroatom doping determines aqueous solubility and self-assembly behaviors for polycyclic aromatic skeletons
Authors: Li Kang , Hu Jia-Min , Qin Wei-Min , Guo Jing , Cai Yue-Peng
Published: August 2022

Developing effective strategies to improve the hydrophilicity or aqueous solubility of hydrophobic molecular scaffolds is meaningful for both academic research and industrial applications. Herein, we demonstrate that stepwise and precise N/O heteroatoms doping on a polycyclic aromatic skeleton can gradually alter these structures from hydrophobic to hydrophilic, even resulting in excellent aqueous solubility. The Hansen solubility parameters (HSP) method shows that the three partial solubility parameters are closely related to N/O doping species, numbers and positions on the molecular panel. The hydrogen bonding solubility parameter indicates that the hydrogen bonding interactions between N/O doped molecules and water play a key role in enhancing hydrophilicity. Moreover, three optimized water-soluble molecules underwent a self-assembly process to form stable nanoparticles in water, thus facilitating better hydrogen bonding interactions disclosed by HSP calculations, NMR and single crystal X-ray analysis. These ensembles even show quasi-solid properties in water from NMR and luminescence perspectives.
Degradation pathways in perovskite solar cells and how to meet international standards
Authors: Zhang Deyi , Li Daiyu , Hu Yue , Mei Anyi , Han Hongwei
Published: August 2022

Commercialization is widely believed to be achievable for metal halide perovskite solar cells with high efficiency and low fabrication cost. However, stability remains a key obstacle for them to compete with established photovoltaic technologies. The photovoltaic community relies on the International Electrotechnical Commission (IEC) standard for the minimum stability assessment for any commercialized solar cell. In this review, we summarize the main degradation mechanisms of perovskite solar cells and key results for achieving sufficient stability to meet IEC standards. We also summarize limitations for evaluating solar cell stability and commercialization potential within the framework of the current IEC standard, and discuss the importance of outdoor testing.
Increased carbon assimilation and efficient water usage may not compensate for carbon loss in European forests
Authors: Montibeller Bruno , Marshall Michael , Mander Ülo , Uuemaa Evelyn
Published: August 2022

Phenological responses of vegetation to global warming impact ecosystem gross primary production and evapotranspiration. However, high resolution and large spatial scale observational evidence of such responses in undisturbed core forest areas is lacking. Here, we analyse MODIS satellite data to assess monthly trends in gross primary productivity and evapotranspiration across undisturbed core forest areas in Europe between 2000 and 2020. Both parameters increased during the early spring and late autumn in nearly half of the total undisturbed core forest area (3601.5 km2). Enhanced productivity drove increased water-use-efficiency (the ratio of gross primary productivity to evapotranspiration). However, productivity increases during spring and autumn were not sufficient to compensate for summertime decreases in 25% of core forest areas. Overall, 20% of total gross primary productivity across all European forest core areas was offset by forest areas that exhibited a net decrease in productivity.
Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy
Authors: Juricic Paula , Lu Yu-Xuan , Leech Thomas , Drews Lisa F. , Paulitz Jonathan , Lu Jiongming , Nespital Tobias , Azami Sina , Regan Jennifer C. , Funk Emilie , Fröhlich Jenny , Grönke Sebastian , Partridge Linda
Published: August 2022

The licensed drug rapamycin has potential to be repurposed for geroprotection. A key challenge is to avoid adverse side effects from continuous dosing. Here we show that geroprotective effects of chronic rapamycin treatment can be obtained with a brief pulse of the drug in early adulthood in female Drosophila and mice. In Drosophila, a brief, early rapamycin treatment of adults extended lifespan and attenuated age-related decline in the intestine to the same degree as lifelong dosing. Lasting memory of earlier treatment was mediated by elevated autophagy in intestinal enterocytes, accompanied by increased levels of intestinal LManV and lysozyme. Brief elevation of autophagy in early adulthood itself induced a long-term increase in autophagy. In mice, a 3-month, early treatment also induced a memory effect, with maintenance similar to chronic treatment, of lysozyme distribution, Man2B1 level in intestinal crypts, Paneth cell architecture and gut barrier function, even 6 months after rapamycin was withdrawn.
Leveraging lessons learned from the COVID-19 pandemic for HIV
Authors: Calder Thomas , Tong Tina , Hu Dale J. , Kim Jerome H. , Kotloff Karen L. , Koup Richard A. , Marovich Mary A. , McElrath M. Juliana , Read Sarah W. , Robb Merlin L. , Renzullo Philip O. , D’Souza M. Patricia
Published: August 2022

The rapid development of COVID-19 vaccines and their deployment in less than a year is an unprecedented scientific, medical, and public health achievement. This rapid development leveraged knowledge from decades of HIV/AIDS research and advances. However, the search for an HIV vaccine that would contribute to a durable end to the HIV pandemic remains elusive. Here, we draw from the US government experience and highlight lessons learned from COVID-19 vaccine development, which include the importance of public-private partnerships, equitable inclusion of populations impacted by the infectious pathogen, and continued investment in basic research. We summarize key considerations for an accelerated and re-energized framework for developing a safe and efficacious HIV vaccine.
Dye-sensitized lanthanide containing nanoparticles for luminescence based applications
Authors: Cheignon Clémence , Kassir Ali A. , Soro Lohona K. , Charbonnière Loïc J.
Published: August 2022

This review aims at providing a survey of the various designs of nanoparticles containing dye-photosensitized lanthanide ions and their use as luminescent probes, from seminal work to the most recent evolutions.
Selective detection of diethanolamine utilizing an LMR/LSPR-based optical fiber sensor
Authors: Kavita  , Jyoti  , Gupta Shruti , Tejavath Kiran Kumar , Verma R. K.
Published: August 2022

Diethanolamine (DEA) is used for amine wash to remove toxic gases such as hydrogen sulphide (H2S) while processing crude oil and in other pharmaceutical products.
A residual dense comprehensively regulated convolutional neural network to identify spectral information for egg quality traceability
Authors: Lin Hualing , He Xinyu , Chen Haoming , Li Ziyang , Yin Chongbo , Shi Yan
Published: August 2022

A residual dense comprehensively regulated convolutional neural network is proposed to extract the deep features of egg spectral information, realizing the identification of eggs laid by hens under different feeding conditions.
Electrocatalyst design for the conversion of energy molecules: electronic state modulation and mass transport regulation
Authors: Wang Jia , Wei Jiankun , An Cuihua , Tang Haolin , Deng Qibo , Li Junsheng
Published: August 2022

Recent progress in the electronic state engineering and mass transport modulation of electrocatalysts is summarized.
Selective NMR detection of N-methylated amines using cavitand-decorated silica nanoparticles as receptors
Authors: Cesari Andrea , Rosa-Gastaldo Daniele , Pedrini Alessandro , Rastrelli Federico , Dalcanale Enrico , Pinalli Roberta , Mancin Fabrizio
Published: August 2022

Nanohybrids prepared by self-assembly of tetraphopshonate cavitands on silica nanoparticles enable selective detection of N-methylated amines at micromolar concentrations via STD-based NMR experiments.
Ultrathin single-crystal PtSe2 nanosheets for high-efficiency O2 electroreduction to H2O2
Authors: Dong Kai , Xu Zhaoquan , He Xun , Zhao Donglin , Chen Haijun , Liang Jie , Luo Yongsong , Sun Shengjun , Zheng Dongdong , Liu Qian , Alshehri Abdulmohsen Ali , Feng Zhesheng , Wang Yan , Sun Xuping
Published: August 2022

Ultrathin single-crystal PtSe2 nanosheets were successfully prepared via an in situ selenization process using commercial Pt/C as a precursor, demonstrating an exclusive 2e− ORR pathway compared to the 4e− pathway of commercial Pt/C.
The role of exchange interactions in the stability of cellulose
Authors: Stovbun Sergey V. , Skoblin Aleksey A. , Mikhaleva Mariya G. , Vedenkin Alexander A. , Gatin Andrey K. , Usachev Sergey V. , Nikolsky Sergey N. , Politenkova Galina G. , Zlenko Dmitry V.
Published: August 2022

Cellulose is sensitive to a permanent magnetic field, which destroys the chain packing.
Hypoglycemic effect of the polysaccharides fromAstragalus membranaceuson type 2 diabetic mice based on the “gut microbiota–mucosal barrier”
Authors: Chen Xiaoxia , Chen Chun , Fu Xiong
Published: August 2022

Astragalus membranaceuspolysaccharides (APP), the main active constituent, possess numerous bioactivities.
A fine single Pd microwire H2 sensor fabricated by using a femtosecond laser for a wide detection range at room temperature
Authors: Zhu He , Dai Yun-Zhi , Sun Xiang-Chao , Xia Hong
Published: August 2022

We reported a fine H2 sensor based on single Pd microwires (SPMs) by femtosecond-laser-induced deposition of palladium nanoparticles (PdNPs), which exhibits excellent H2 sensing performance.
Enhanced luminescence of erbium silicate: interstitial lithium directly regulates the lattice structure of erbium compound crystals
Authors: Shang Huabao , Yang Deren , Li Dongsheng
Published: August 2022

Better luminescence properties of Er2Si2O7 films, including higher luminescence intensity, LDP and radiative transition rate, have been achieved by doping Li.
Recent progress of single-halide perovskite nanocrystals for advanced displays
Authors: Yao Jisong , Xu Leimeng , Wang Shalong , Yang Zhi , Song Jizhong
Published: August 2022

Single-halide perovskite nanocrystals have attracted attention for PeLEDs with the CIE coordinates achieving Rec. 2020 standard because they could significantly reduce phase separation in mixed-halide perovskites.
Size-dependent properties and unusual reactivity of novel nonplanar heterocycloarenes
Authors: Zhu Jiangyu , Li Wenhao , Zhang Ning , An Dongyue , Zhao Yan , Lu Xuefeng , Liu Yunqi
Published: August 2022

Two novel fully fused heterocycloarenes consisting of nonplanar phenothiazine building units have been designed and successfully synthesized, which show size-dependent properties and unusual reactivity.
A two-dimensional Be2Au monolayer with planar hexacoordinate s-block metal atoms: a superconducting global minimum Dirac material with two perfect Dirac node-loops
Authors: Wang Meng-hui , Cui Zhong-hua , Wang Sheng , Li Quan , Zhao Jijun , Chen Zhongfang
Published: August 2022

A topological superconductor, named Be2Au monolayer, containing planar hexacoordinate s-block metal (Be and Au) atoms was theoretically designed by rationally assembling related clusters.
High-throughput screening of transition metal doping and defect engineering on single layer SnS2 for the water splitting hydrogen evolution reaction
Authors: Xu Ruixin , Bo Tingting , Cao Shiqian , Mu Nan , Liu Yanyu , Chen Mingyan , Zhou Wei
Published: August 2022

The HER activity of SnS2 nanosheet with transition metal doping and S vacancy defect was screened through DFT calculations. The modified pz band center combining with a new descriptor φ is proposed to predict the HER activity.
Crystalline H-aggregate nanoparticles for detecting dopamine release from M17 human neuroblastoma cells
Authors: Reddy Nitin Ramesh , Dicce Arianna , Ma Yiping , Chen Li-Mei , Chai Karl X. , Fang Jiyu
Published: August 2022

Crystalline H-aggregate nanoparticles of a cyanine dye were developed as a highly efficient photo-induced electron transfer probe for the detection of dopamine, which shows that the dopamine release from cells was enhanced by nicotine stimulation.
A tailored and red-emissive type I photosensitizer to potentiate photodynamic immunotherapy
Authors: Zhou Sirong , Li Ruipeng , Li Ying , Wang Yunxia , Feng Liheng
Published: August 2022

A tailored type I PS for imaging-guided photodynamic immunotherapy is developed. The work enhances the killing effect of PDT against hypoxic solid tumors and boosts the T-cell immune response to residual and metastasis tumor cells.
Construction of a fully conjugated cross-linked hole-transport film based on ethynyl to enable high mobility for efficient solution-processed OLEDs
Authors: Peng Cancan , Liu Hongli , Han Xinjun , Zhang Fei , Wang Shirong , Li Xianggao
Published: August 2022

Ethynyl-based cross-linkable hole transport material E-TPD was designed to obtain fully conjugated cross-linked hole transport film with preferable hole mobility. The solution-processed OLED gained excellent performance with CEmaxof 60.74 cd A−1.
In situ preparation of Bi2O2Se/MoO3 thin-film heterojunction array flexible photodetectors
Authors: Yang Ming , Zhang Xiaoqiang , Zhou Hongxi , Fu Gui , Zhou Xin , Lian Yunlun , Hao Jinxin , Yu He , Zhu Xinyu , Wang Jun
Published: August 2022

The Bi2O2Se/MoO3 heterojunction has the characteristics of high stability and detection in the optical communication spectrum, which provides a simple and effective method to fabricate large-scale, fast response, broadband flexible array optoelectronic devices.
Tunable concentration/excitation-dependent deep-red and white light emission in single-phase Eu2+-activated Sc-based oxide phosphors for blue/UV-LEDs
Authors: Huang Shuai , Shang Mengmeng , Deng Minliang , Yan Yu , Dang Peipei , Lin Jun
Published: August 2022

Novel Sr3Sc4O9:xEu phosphors with tunable luminescence are firstly reported. All experimental results suggest the utilization potentiality of the multifunctional Sr3Sc4O9:xEu phosphors in agricultural and full-spectrum general lighting.
Tailoring interlayer magnetic coupling to modify the magnetic properties of FeCl2 bilayers by self-intercalation
Authors: Li Rui , Jiang Jiawei , Bai Haili , Mi Wenbo
Published: August 2022

The interlayer magnetic coupling transforms from the super–super-exchange to double-exchange by self-intercalation. The EMCA and TC of the self-intercalated FeCl2 bilayer can be modulated by the intercalated concentration.
Optimisation method for carbon black distribution of polypropylene‐based semi‐conductive screen materials and its effect on charge emission behaviour at screen/insulation interface
Authors: Yang Jiaming , Zhang Rui , Yang Xu , Sun Zhi , Zhao Xindong , Zhao Hong , Wang Xuan , Li Lin , Liu Heqian
Published: August 2022

The semi‐conductive (SC) screen materials used in polypropylene (PP)‐based cables are usually multi‐component composites. Polypropylene shows poor compatibility with carbon black (CB), and CB particles tend to disperse in the elastomer phase, which results in CB non‐uniform dispersion in screen materials. The non‐uniform distribution of CB will cause abnormal electric fields at the screen/insulation interface and affect insulation performance. This paper prepared modified PP grafted by molecule maleic anhydride, and four PP‐based SC shielding materials were blended in combination with PP, PP‐g‐MAH, and thermoplastic elastomer (POE) as matrix resin. The CB distribution, electrical conductivity, and basic physical properties of the shielding material were characterised. Different screen materials were served as electrodes to test their effects on the space charge and conductivity characteristics of insulation. The relationship between the macroscopic properties and the distribution characteristics of CB was discussed. Results show that the selective dispersion of CB in screen material was improved by PP‐g‐MAH and the surface electric potential distribution was homogenised. Charge emission at the screen/insulation interface and conductivity can be reduced by homogenising the CB distribution. CB/PP‐g‐MAH/POE prepared in this paper exhibits relatively uniform CB distribution, which can reduce the charge emission from the screen/insulation interface.
A hybrid‐driven continuous‐time filter for manoeuvering target tracking
Authors: Xiong Wei , Zhu Hongfeng , Cui Yaqi
Published: August 2022

This paper considers the problem of target tracking in complex manoeuvering scenarios with a lack of relevant prior knowledge. This is a challenge for classical model‐based manoeuvering target tracking algorithms because they rely heavily on accurate domain and prior knowledge of target motion. To address this problem, we propose a hybrid‐driven continuous‐time filter algorithm in this paper, which combines the advantages of the model‐driven and data‐driven. We use the stochastic differential equation (SDE) with the acceleration model as the basic framework of the proposed algorithm. In order to deal with unpredictable manoeuvres and unknown perturbations, we adopt neural networks as data‐driven to estimate target accelerations and compensations of composite perturbations in real time using historical and current measurements. And the direction of gradient descent of the neural network is constrained by the motion model, thus the learning efficiency of the network and the interpretability of the proposed algorithm is improved. The proposed algorithm can simultaneously utilise historical trajectory information and domain knowledge as hybrid‐driven to achieve complex manoeuvering target tracking with little prior information. Experimental results demonstrate the superiority of our algorithm in tracking accuracy, robustness and environmental adaptability.
Study of AC - 20 asphalt mixture ratio on the runway of of Chang Sha Airport
Authors: Tian Shuaituan , Li Zhiyan , Guo Lei , Yan Yapei
Published: August 2022

After years of use, there’s oil loss on the asphalt pavement. the bond strength of aggregate decreases. Loose threshing is serious. In order to improve the pavement performance, Extend the service life of pavement, Improve the safety of aircraft operation. We test the AC-20 modified asphalt mixture on the taxiway and runway of Chang Sha Airport from many factors, including raw materials, admixtures, gradation design, optimum ratio of oil to stone, then we find the best ways to resolve it.
Research of SMA - 13 asphalt mixture ratio on the taxiway of HuangHua Airport
Authors: Tian Shuaituan , Yan Yapei , Wang Peng
Published: August 2022

Because of the large load and large impact force of airport pavement under, it often appears the phenomenon of serious rut. In order to improve this kind of phenomenon, combined with the taxiway of HuangHua Airport area reconstruction project, we analyze the upper layer type of SMA-13 modified asphalt mixture ratio design. we analysis from raw material selection, mixture gradation design and admixture added, and finally choose the excellent performance of asphalt mixture.
Research on Palletizing Robot System of Multi - axis Synchronous Control Technology
Authors: Yang Yuan , Zhang Lei , Qiang Ligang , Wang Jinbing , Zhang Yong , Yang Xudong
Published: August 2022

Due to the increasing demand for personalized objects, the palletizing packaging of personalized objects has attracted people’s attention. To improve the efficiency of the palletizing system, a palletizing robot based on multi-axis synchronous control technology is proposed in this paper. The robot takes SIMATIC S7 - 1200 PLC as the control core, uses the master command synchronization method to achieve multi-axis synchronization control, and realizes human-computer interaction through PROFINET communication with the touch screen. The multi-sensor is connected with the input and output modules of the PLC, and the review of the grasping object is realized. After the robot is put into use, the flexibility of the palletizing system is improved, the multi-axis synchronous control technology is improved, and the palletizing efficiency of personalized objects is greatly increased.
Research on a new high-quality and high-efficiency SLM forming method based on interlayer strategy
Authors: Wang Peng , Chen Dongju , Li Gang
Published: August 2022

To ensure the forming quality of SLM and to improve the forming efficiency of SLM, this paper investigates the forming effect of Ti6Al4V specimens formed by SLM based on an interlayer strategy. The conditions for improving the relative density of the specimens are high laser power, small point distance, long exposure time and long hatch spacing. High laser power provides sufficient laser energy density in the formation of thicker powder layers, reduced point distance ensures wetting behavior of the melt pool, longer exposure time provides the time required to fully melt the powder and increased hatch distance facilitates dispersion of the laser energy density. Process parameters have a strong influence on the relative density of SLM formed specimens, and by adjusting the process the highest density of 99.99% can be achieved. The microstructure of the specimens consisted mainly of acicular martensite α′ and columnar β grains due to the effects of repeated thermal cycling. Due to the presence of martensite α′, the tensile and yield strengths of the specimens are increased, but the elongation of the specimens is reduced.
THOR 50th Dummy Neck Calibration Analysis Based on Bi-LSTM Neural Network
Authors: Xu Gang , Yu Ruihan , Duan Bingxu
Published: August 2022

In this paper, a neural network model is established based on the neck calibration data of the Thor50th crash test dummy using a bi-directional long and short-term memory (Bi-LSTM) neural network algorithm. The model input is the factors affecting the neck calibration test, and the output is the maximum value of My in the neck calibration test, and the accuracy of the model is calibrated by comparing it with the actual calibration data. The accuracy and suitability of the Bi-LSTM neural network model is further verified by comparing with the radial basis (RBF) neural network algorithm.
Research on straightness calibration method of straight edge working face based on electronic level
Authors: Yang Yi , Wang Tao , Dai Liwei
Published: August 2022

A straightness calibration method of straight edge working face based on electronic level is proposed. According to the proposed calibration method, the evaluation model of measurement uncertainty is established, and the source of uncertainty is analysed. The expanded uncertainty is less than one third of the maximum allowable error required by the calibration specification, which verifies the feasibility and effectiveness of this calibration method.
Effect of anodic oxidation of 2024-T3 aluminum alloy on interface properties of metal fiber laminates
Authors: Zhou Zhiqiang , Qian Changjiang , Hu Zonghao , Yang Feiyuan , Lou Meiduo , Xie Guangan
Published: August 2022

Interlaminar fracture failure is the main factor restricting the development and application of fiber metal laminates. In this paper, the interlayer bonding properties of 2024-T3 aluminum alloy plates with different surface treatments were compared and studied through lap-shear experiments. Compared with the aluminum plate treated with acid and alkali corrosion, the interlaminar shear strength of the aluminum plate after sulfuric acid anodization increased by 34.3%. After different surface treatments, experimental stressstrain curves of 2024-T3 aluminum alloys reveal the enhancement mechanism and changing trend of interlaminar shear strength.
Advances in water-resistant modification of aqueous acrylic resins: modification methods, mechanism of action
Authors: Wei Jiajun , Ouyang Chunfa , Shan Xiaoqian , Gao Qun , Zheng Kangsheng , Luo Wei
Published: August 2022

Waterborne acrylic resin is widely available in architectural coatings, road adhesives, etc. Its non-toxicity, non-irritating odour, and low cost are characteristics that have received increasing attention in recent years. Concerning the water-resistance of the resin, this review introduces the effect of inorganic materials like silane coupling agents, fluorine silicone, and copolymers on the hydrophobic properties of aqueous acrylic resins, analyses and discusses the mechanism of action of various methods and their factors affecting hydrophobic properties, such as the formation of cross-linked structures and micro-convex structures on the surface, also points out the problems and challenges in the water-resistance modification of aqueous acrylic resins.
Digital realization method of FFT and its application in adjusting velocity damping coefficient of inertial navigation system
Authors: Wang Yujie , Zhang Yang , Ma Xintai , Gao Minghao , Zheng Zhipeng
Published: August 2022

Aiming at the velocity damping feedback system commonly used in inertial navigation, this paper proposes the principle of decomposing the output attitude of inertial system based on FFT algorithm and gives the principle of spectrum adjustment ratio. The effectiveness of the algorithm is verified from two aspects: data simulation and actual system solution. In addition, in the design and implementation of FFT algorithm, the butterfly computation of operator symmetry is applied to effectively reduce the complexity of the algorithm, and the dual core chip technology is applied to reduce the impact of the complex algorithm on the system timing. The engineering applicability of the algorithm is demonstrated.
Research on the Extrusion Process of belt with Notch Descrition
Authors: Liu Qi , Wang Yuwei , Zhu Wenfang , Zhao Na
Published: August 2022

The extrusion process of the belt is a process in which the belt and the inner bore of the barrel undergo complex contact and collision, and the rifling gradually penetrates the belt, so that the material of the belt continues to fail and destroy. It has high instantaneous, strong impact, high temperature, high-speed change. There is a big gap between the existing theory and the actual extrusion process, and it is urgent to carry out research work on this problem. This paper analyzes the basic characteristics of elastic and plastic deformation during the extrusion process of the belt, and establishes the Johnson-Cook constitutive model of the deformation, flow and failure process of the belt material. Explicit dynamic calculations are carried out in the process of belt extrusion, and the contact problems, deformation of the belt and material flow problems during the extrusion process of the belt are discussed in depth
Community of primary-level: governance forming logic, realistic dilemma and construction paths-focus on less developed areas
Authors: Zhou Ping
Published: August 2022

One of the working principles of promoting the modernization of primary-level governance system and governance capacity is: “basing on collaboration, participation, and benefit sharing and fostering a community of primary-level governance in which responsibilities are shared and duly fulfilled, and achievements are enjoyed by all.” Based on this, we deeply analyzed its profound connotation, forming logic and realistic predicament, put forward the practical path of building grassroots governance community, which aims to provide a framework explanation for cultivating a consciousness of grassroots community, condensing value consensus and promoting grassroots governance efficiency.
Research on the influencing factors of excessive behavior of Bilibili video platform
Authors: Lv Dong , Wei Qiang , Li Jiao , Wang Rui
Published: August 2022

Bilibili is a cultural community and video platform for China’s younger generation that is highly aggregated. Currently, the excessive use of Bilibili is becoming increasingly serious. Based on social cognition theory and uses and satisfactions theory, this study adopts questionnaire survey to explore the influencing factors of Bilibili users’ overuse behavior. Correlation analysis and binary logistic regression analysis were conducted on 305 valid questionnaires collected through the online platform to verify the research hypotheses. The results show that entertainment motivation, learning motivation, social need, stress relief, sense of belonging, and peer influence, have significant positive effects on Bilibili users’ overuse behavior. Finally, this study proposes three recommendations to guide people to use Bilibili platform more scientifically and appropriately, including the platform should take the responsibility of necessary warning and constraints, guiding users to correctly understand excessive behavior and strengthen personal media literacy.
Have the construction of China’s software industry bases improved the level of manufacturing servitization?
Authors: He Dan , Miao Pengjia
Published: August 2022

This paper takes the software industry base of national torch plan as the research object, describes its construction process and distribution characteristics for more than 20 years, and uses the cross-sectional data of 2007, 2012 and 2017, Empirically test the impact of software industry base on the service level of manufacturing industry in the region, and further analyze the regulatory effect of regional intellectual property protection intensity. It is found that the overall scale of the national software industry base has expanded steadily in recent 20 years, but the spatial distribution is extremely unbalanced. The software industry base in the eastern region is significantly stronger than that in the central and western regions in terms of base number and base income. The construction and development of software industry base can significantly improve the service level of manufacturing industry in the region. After the robustness test, the conclusion is still valid. The results of regional heterogeneity test show that with the deepening of industrialization, the construction of software industry base plays a more obvious role in improving the service-oriented manufacturing industry in the eastern region. The results of industry heterogeneity test show that the construction of software industry base can more effectively improve the service-oriented level of technology intensive manufacturing industry. The results of regulation effect test show that the strength of local intellectual property protection and strengthening the construction of software industry base have a positive regulation effect on the service level of manufacturing industry.
Exploration and practice of BOPPPS model in the teaching reform of pharmaceutics
Authors: Yao Liping , He Gang , Zhang Lei , Liu Keyue , Ling Yun , Zhao Jianguo
Published: August 2022

Pharmaceutics is one of the core courses of pharmacy with strong practicality, wide range of knowledge and strong professionalism, and effective teaching model is crucial for its teaching. The BOPPPS model was one of the effective teaching models, which emphasize students’ all-round participatory learning, and can fully mobilize students’ subjective initiative. In this paper, the BOPPPS model has been applied to the reform of pharmaceutics teaching based on Mooc classroom as the information support platform of teaching process. The results revealed that the application of BOPPPS model in pharmaceutics teaching could effectively improve students’ learning enthusiasm, and the academic performance and teaching effect were significantly improved. The application of BOPPPS teaching model in pharmaceutics teaching is conducive to improving the level of professional education and cultivating high-quality professionals with rich theoretical knowledge, strong operational ability and “craftsman spirit”.
Changes of knowledge sources concerning public sports policy (2001-2020): based on core journals of China sports science
Authors: Yu Yongping , Lin Ming , Liang Xiao , Xi Zenghui , Wang Yifei , Sun Jianbo , Niu Dayu , Mu Xiaokun , Yang Zhuyu , Yang Jie , Wang Lixin
Published: August 2022

This paper systematically reviews changes of knowldege sources concerning public sports policy based on core journals of China sports science. Author selected and analyzed all references of peer-reviewed articles published in core journals of China sports science (2001-2020) with reference number, reference resource, language distribution and discipline category. Results: over the past years, books and journals are the most top references. As far as references language is concerned, there were Chinese, English, German, and Japanese, and others language. it appeared the change that is from Chinese to foreign language in cited references, especially, English references have a majority of increasing in recent years. In addition, discipline distribution of references has changes that are obvious from single discipline to multiple disciplines, and the effect of other disciplines on public sports policy is significant.
Conception of strategic cooperation between universities and community elderly service centers
Authors: Wu Jing
Published: August 2022

At present, about 90% of the elderly in the country choose to live at home. For various reasons, many elderly people feel lonely, even with children around. Using the methods of questionnaire survey and indepth interviews, this paper visited the elderly service centers in 15 communities in Wuhan, and conducted a questionnaire survey on 412 elderly people over 60 years old. The results showed that 54% of the elderly often go to community elderly service centers to participate in activities, but 30% of the elderly never go; the elderly who go to the community have the highest satisfaction with community entertainment activities such as mahjong room and square dance, 50%are satisfied; elderly people with higher education level are less likely to participate in community activities; the elderly generally lack spiritual comfort; 37% of them want to use their expertise to contribute to the community but do not know how to start. To this end, this paper proposes to take advantage of Wuhan’s 83 colleges and universities to seek strategic cooperation between universities and neighboring communities, so that relatively young healthy elderly people aged 60-75 can have lifelong learning opportunities and continue their spiritual growth. At the same time, it promotes the effective combination of theoretical knowledge and social practice of teachers and students in universities. This move will enhance the social participation and well-being of the elderly and promote the construction of an elderlyfriendly society.
Research on economic policy system evaluation methods
Authors: Liu Gengran , Dong Gaofeng , Liu Qiong , Wang Menglong
Published: August 2022

Great progress has been made in construction of economic policy system in recent years. Nevertheless, there are also difficulties in accurate inquiry, efficient use and comparative analysis. In a bid to address critical problems of the existed system, this paper builds an intelligent policy system platform. By adopting the big data and artificial intelligence technologies, a number of functions such as accurate matching, system classification, and the analyses of relevance, life cycle, response level, time-effectiveness, self-consistency, maneuverability and so on are made available, so as to put in place a policy evaluation management system which is systematic, multi-dimensional and intelligent.
Research on the application of mixed reality technology in the field of art design
Authors: Sha Chunfa , Zeng Hanlei , Wu Beibei , Zhang Wenli , Guo Huaquan , Su Wencheng
Published: August 2022

Aim: summarize the application of mixed reality technology in the field of art design and analyse its shortcomings and trends. Method: by searching the Web of science as the main source of information to explain the basic concept and development of MR and state of art in product design, display design and interactive design. Discuss the pros and cons of mixed reality technology in human-computer interaction, hardware, and user experience. Result: Mixed reality technology is widely used in art, design, especially in product design, display design, and interactive design. The future trend of mixed reality technology is summarized the combining status of market and industry. Conclusion: The application of mixed reality technology in the field of art design is already drawing more and more attention from industry, but it still lacks enough attention from academia community. This paper systematically introduces the state-of-the-art applications and trends of MR in the field of art design which helps readers to get an insight on this fascinating research area.