bluuebunny/crossref_metadata_2025 huggingface dataset:
Experience of primary thoracoplastics in the treatment of resistant tuberculosis of the lungs
Authors: Opanasenko M.S. , Tereshkovych O.V. , Konik B.M. , Shalagay S.M. , Shestakova O.D. , Kalenychenko M.I. , Stepaniuk A.M. , Lysenko V.I. , Levanda L.I. , Bilokon S.M.
Published: September 2022

Objective — to present the own results of the use of extrapleural thoracoplasty (ET) for the treatment of resistant pulmonary tuberculosis.

Materials and methods. A retrospective analysis of the results of the use of extraleural thoracoplasty (EPTP) in patients with multidrug-resistant pulmonary tuberculosis and tuberculosis with extensively drug resistance, operated in the NIFP clinic of NAMNS in the period from 01.01.2004 to 01.07.2022 was conducted. Patients were divided into two clinical groups: the main — 28 patients who underwent a modified EPTP technique, and the control group — 13 patients who underwent EPTP according to the traditional Bogush technique. When evaluating the results of surgical treatment, each group was divided into subgroups according to the resistance profile of Mycobacterium tuberculosis: A — patients with multidrug-resistant pulmonary tuberculosis, B — patients with tuberculosis with extensively drug resistance. Male patients predominated in both groups. The age range of patients is from 21 to 44 years. The groups did not differ statistically significantly in terms of mean age. Operative treatment was more often performed on the right side. The duration of the period from the onset of the disease to the operation varied from 16 to 60 months (main group — (24.6 ± 1.1) months, control group — (22.8 ± 2.6) months).

Results and discussion. Extrapleural thoracoplasty (EPTP) is a rather traumatic surgical intervention with a significant cosmetic defect and certain functional losses. Recently, such operations are performed less often, thanks to the development of new schemes of anti-tuberculosis therapy, and the associated better outcome of treatment of patients with resistant forms of tuberculosis. But if there are indications, the use of EPTP makes it possible to achieve results unattainable when using only conservative treatment. When performing EPTP, a complex of preoperative preparation measures, operational and technical features of the modified EPTP technique, measures to prevent postoperative complications and recurrences of TV was developed, which allowed to improve the results of surgical treatment in patients of the main group compared to the control group by 12.9 and 11.8 % and reduce the level of postoperative mortality.

Conclusions. Performing EPTP, in the presence of widespread forms of tuberculosis, when it is not possible to perform resection interventions, is the method of choice, which allows improving the effectiveness of treatment of this category of patients.
Business Development Strategy For Improving Sales In Start Up Retail Building Material (Case Study: Hero Castle)
Authors: Arifah Alfin Nur
Published: September 2022

Hero Castle is a retail company that started its business on February 1, 2015, located in Raya Pemda street Singaparna Tasikmalaya. Hero Castle sells building finishing materials such as ceramic/granite for the floors and walls, sanitary and kitchen tools, paint, glue, and building accessories for doors and windows. As a new company that has been in operation for eight months, Hero Castle needs to maintain its growth with the right business strategies. This thesis will discuss about the implementation of business strategies in Hero Castle to improve sales. Based on the sales data per month from Hero Castle,  a decrease in sales is evident in the second to fourth months. In this study has applied a hybrid strategy to improve sales in Hero Castle. This study is divided into two periods, namely the first period from February to May. The second period is from June to September. The first period is the period before the implementation of a hybrid strategy, while the second period is the period after treatment or after the application of a hybrid strategy. The result in the second period ( June – September ) shows the average sales increased to 71.38% from the previous period ( February – May ). The main weaknesses and threats found based on the results of the SWOT analysis are a lack of capital and technology. Thus the implementation plan will be focused to fix these two problems. To maintain and improve business performance Hero Castle has a strategic implementation plan which is divided into three steps, namely improving the quality of human resources, improving management distribution, and utilizing system technology.
ANALYSIS THE EFFECT OF BRAND EXPERIENCE AND BRAND INNOVATION ON BRAND LOYALTY WITH BRAND TRUST AS A MEDIATION VARIABLE
Authors: Maura Nadya Desna , Wibowo Januar , Candraningrat Candraningrat , Alif Fianto Achmad Yanu
Published: September 2022

Technological developments have had a great influence on competition in the industrial world, especially in the beauty industry. To win the competition, it is important for a company to build customer loyalty. Several studies that have been conducted have found a significant relationship between brand experience and brand innovation on brand loyalty. Apart from the many studies examining the effect of brand experience and brand innovation on brand loyalty, inconsistency of results is still found where there is a group of researchers who find that there is a significant effect between brand experience and brand innovation on brand loyalty and there are other groups of researchers who find no significant effect between brand experience and brand innovation on brand loyalty. To fill this gap, this study will use the brand trust variable as a mediating variable. The purpose of this study was to further investigate the relationship between brand experience and brand innovation on brand loyalty with the brand trust variable as a mediating variable. This study uses a quantitative approach using the structural equation modeling (SEM) method to analyze the data. The object of this research is the grace and glow brand using 160 respondents located in Surabaya.
ANALYSIS OF CONSUMER ATTITUDES TOWARDS TELEVISION MEDIA ADVERTISING
Authors: Suyanto Mohammad , Abdulrahim Muslimin
Published: September 2022

As consumers, everyone becomes the target of advertising, even all parts of the human body are targeted by advertisements. Producer use various advertising media hoping to influence consumer behavior. One of the advertising media is television. This study focuses on the problem of consumer attitudes towards consumers towards television advertising. This research was conducted in the city of Surabaya. Sampling was done by simple random sampling method. Data were collected by distributing questionnaires with data analysis using Fishbein's attitude model.

The results of the study indicate that consumer attitudes towards television media advertising are based on advertising attributes: 1) Product information; 2) Social roles and image; 3) Entertainment; 4) Good for the economy; 5) Falsehood; 6) Corruption of values; 7) Materialism, is positive. Two things that need to be considered in advertising from the results of this study are: 1) Analysis of consumer attitudes towards advertising is important as a basis for preparing promotional strategies and programs, especially in the field of advertising; 2) Determination of advertising material needs to pay attention to the values ​​that exist in the community.
THE EFFECTIVENESS OF RESTRUCTURING POLICY IN BUMN BANKS DURING THE PANDEMIC
Authors: Sulistiyowati Liliek Nur , Sari Putri Oktovita , Purwaningsih Ananda Nunung
Published: September 2022

The pandemic condition has made many sectors affected, one of which is banking. Bank Indonesia is one of the central banks that provide regulatory stimulus to maintain the stability of the banking system in the form of financing relaxation policies or waivers in customer financing installments. It is hoped that the level of health of the national banking can be well conditioned. This research aims to find out whether the restructuring policy that has been programmed by the government has been effective. This research was conducted at a state-owned bank in the Madiun Residency. The method used in this study was a simple regression analysis using the help of SPSS Version 26. The results of this study show that the restructuring policy programmed by the government has been effective. It is proven by the improvement of problematic NPLs after the restructuring, where previous debtors had difficulty in paying their obligations. Restructuring of state-owned banks can be carried out in several aspects, namely reducing interest rates, unemployment of credit interest arrears, reducing principal arrears, extending the term, taking over debtor assets, and converting loans into temporary capital.
The Influence of Human Capital on Organizational Performance
Authors: Hidayat M. Taufiq , Widodo Arifin Puji
Published: September 2022

Currently, the economic downturn in various parts of the world has made human capital increasingly important with increasing globalization and the saturation of the job market.In order to increase economic growth by giving more time and effort, both developed and developing countries place an emphasis on human resource development.To enter the international arena, human resource development is one of the basic solutions.For this, companies need to invest the necessary resources to develop human resources that have a greater impact on performance.This paper reviews the effects of human capital having a direct impact on firm performance from various critical perspectives.Company performance in terms of financial and non-financial performance.Finally, this paper proposes an initial model that explains the relationship between human capital and firm performance.
The Impact Of Macroeconomics, Liquidity, Asset Structure On Firm Value In The Heavy Construction & Civil Engineering Sub-Sector On The Indonesia Stock Exchange
Authors: Rahmiyati Nekky , Rachmawati Titiek , Dyah Erwin
Published: September 2022

Study aims to see the relationship between macroeconomic, liquidity , asset structure variables, on firm value with profitability and capital structure as an intervening variable in the in the Heavy Construction & Civil Engineering Sub-Sector on the Indonesia Stock Exchange 2019-2021 The types of research are quantitative, the number of samples is 15 and the sampling technique is purposive sampling . This study uses SEM (Structural) analysis. Equation Modeling) based on component or variance, namely Partial Least Square (PLS), using Smart PLS 3.0 software. According to the findings of the study, macroeconomic variables had positive effect  on firm value and capital structure but not significant, macroeconomic variables had a negative effect  on  profitability   but not significant. Assets structure variables had a positive effect on profitability  and capital structure but not significant. Assets structure variables had a negative effect  on firm value  but not significant. Liquidity  had a negative effect  on  profitability and firm value but not significant, Liquidity  had a negative effect  on capital structure but significant . Profitability had a positif effect  on firm value but not significant. capital structure variables had  a negative effect on firm value but significant
ENZYME BASED RECYCLING PROCESSES
Authors: Guebitz Georg M. , Quartinello Felice , Ribitsch Doris
Published: September 2022

Novel strategies allowing environmentally friendly recycling of plastics are strongly needed. Enzymes have shown high potential, especially for the recovery of building blocks from multilayer materials which will be discussed in this paper. It has been shown that enzymes can specifically hydrolyze and solubilize certain components of blended packaging materials or mixed wastes. This allows a step—wise recovery of valuable building blocks which can be used for re-synthesis or for bioproduction (e.g. recovered glucose). However, despite the high potential of biocatalysts, even more efficient enzymes are required for economic industrial implementation. In this paper, which is based on a contribution to the SUM 2022 conference, we will consequently demonstrate how enzyme discovery can lead to more powerful tools for plastics recycling and provide some examples.
Los canteros urbanos como parte del paisaje biocultural de Bariloche (Argentina): riqueza de especies y decisiones de manejo
Authors: Rovere Adriana
Published: September 2022

Introducción: En áreas urbanas, los canteros con especies ornamentales, brindan estructura y color, atraen polinizadores, funcionan como corredores ecológicos, acercan la naturaleza, y ofrecen bienestar a los seres humanos. La flora urbana, puede ser reservorio de biodiversidad, o fuente de invasiones según los criterios de selección.
Objetivos: Se estimó la riqueza de especies, formas de vida, familias botánicas y origen de las plantas utilizadas en canteros de Bariloche.
M&M: La ciudad de Bariloche, se halla inmersa en el Parque Nacional Nahuel Huapi, posee características pluriculturales. Se estudiaron 1120 canteros ubicados sobre las veredas, con distinto manejo, 560 de gestión municipal y 560 vecinal. 
Resultados: La riqueza fue de 121 especies, siendo las más utilizadas Lobelia erinus (23,3%) y Clarkia amoena (19,7%). De las 54 familias botánicas representadas, las de mayor frecuencia de uso fueron Rosaceae (28,5%, repartida en 9 especies), Campanulaceae (23,7%, 2) y Compositae (20,4%, 18). Predominó el uso de plantas herbáceas (70 especies), seguidas por arbustos (43), renovales arbóreos (6), y enredaderas (2). Los vecinos manejan mayor diversidad de plantas y especies nativas (92 especies/11 nativas), que el municipio (64/4). La presencia de elementos nativos (e.g., Alstroemeria aurea y Fucsia magellanica) tiene implicancias para la conservación; mientras que las especies invasoras representan riesgo (e.g., Hedera helix y Cytisus scoparius) y deberían ser controladas. 
Conclusiones: Se concluye que la flora de los canteros representa parte del paisaje biocultural de la región, como escenarios dinámicos construidos a lo largo del tiempo, presentando similitudes con los patrones de selección a nivel mundial.
Las maderas nativas en la arquitectura vernácula de la Puna Jujeña, Argentina: ¿continuidad o reemplazo?
Authors: Barbarich Maria Florencia
Published: September 2022

Introducción: Las técnicas de construcción con tierra tuvieron una alta relevancia para la producción de la arquitectura en toda el área andina. Se trata de un conjunto de prácticas y saberes diversos, integrado en una cultura constructiva indisociable de otros aspectos de la vida social. Dentro de las materias primas de origen mineral, animal o vegetal y de múltiples resoluciones para cada parte de la casa, la madera es fundamental para la estructura de la cubierta. Los principales recursos vegetables maderables de la región, la queñoa (Polylepis tomentella) y especialmente el cardón (Trichocereus atacamensis) tienen un rol protagónico. El objetivo fue estudiar la vigencia de su uso en las arquitecturas actuales. 
M&M: El trabajo se desarrolló en el departamento de Susques, Jujuy, desde el enfoque de la etnobotánica cualitativa, utilizando principalmente la metodología etnográfica. Se trabajó con 15 colaboradores locales, alcanzando las 100 personas en instancias grupales.
Resultados: Evidencian que el uso de estas maderas ha disminuido en los últimos años, pero su relevancia no ha perdido vigencia en el relato de los pobladores. Así mismo, demuestran que entre las causas se entremezclan leyes provinciales que prohíben su uso, menor tiempo de permanencia en el campo resultando en la interrupción de la recolección de madera y la introducción de materiales provenientes de tierras bajas. 
Conclusión: La conservación del patrimonio arquitectónico implica la continuidad de ciertas prácticas e involucra materialidades específicas, su identificación y conocimiento permite su valoración y la búsqueda de estrategias para su permanencia.
Optimal Cutoff Value of 1-Hour Postload Glucose to Identify Insulin Resistance in Women with Polycystic Ovary Syndrome
Authors: Chun Sungwook , Lee Sihoon
Published: September 2022

Background: Despite the active researches recently conducted into the relationship between 1-h postload glucose (1-h PG) during standard oral glucose tolerance test and future risk of type 2 diabetes, research regarding the clinical capacity of 1-h PG to assess insulin resistance in those with polycystic ovary syndrome (PCOS) is still insufficient. The purpose of this study was to investigate the optimal 1-h PG cutoff value to identify insulin resistance in women with PCOS. Methods: One hundred fifty-three women aged 18 to 35 years who were diagnosed with PCOS were enrolled in this study. Insulin resistance was defined as having abnormal insulin sensitivity or hyperglycemia. Spearman’s rank correlation coefficient and receiver operating characteristic (ROC) curve analyses were conducted to assess the relationship between 1-h PG and other parameters and to determine the optimal 1-h PG cutoff for identifying insulin resistance, respectively. Results: Significant correlations were observed between 1-h PG, 2-h PG and fasting glucose, and other fasting-state insulin sensitivity assessment indices, other than fasting insulin level. The optimal 1-h PG threshold value for identifying insulin resistance was 138.5 mg/dL. Categorization of patients based on the 1-h PG threshold showed significant differences for all laboratory variables related to insulin sensitivity/resistance, other than fasting insulin. Conclusions: Our results suggest that a 1-h PG value of ≥138.5 mg/dL may be a promising assessment index for identifying insulin resistance in women with PCOS.
COVID-19 Vaccination and Pregnancy
Authors: Ignaszak-Kaus Natalia , Chmaj-Wierzchowska Karolina , Wszołek Katarzyna , Wilczak Maciej
Published: September 2022

Objectives: A review to assess the safety, efficacy, COVID-19 vaccination acceptance and awareness in pregnant women. Machanism: Pregnant women diagnosed with COVID-19 are characterized by more frequent hospitalization in intensive care units and are at three times higher risk of preterm; their newborns more often need invasive ventilation. Vaccination is the most effective preventive measures against SARS-CoV-2, but there are still questions about safety and immune response. Pregnant women were not included in study groups during phase III clinical trials. Findings in Brief: Vaccination during pregnancy is not associated with an increased risk of obstetric or neonatal complications; scientific communities recommend vaccination for pregnant women, those planning for pregnancy and those who are breastfeeding. Unfortunately, knowledge regarding COVID-19 vaccination and willingness to take vaccine during pregnancy is low. Conclusions: General practitioners and obstetricians have a large role in increasing public awareness of COVID-19 vaccination. No evidence of teratogenicity of the vaccine has been found.
Effect of Thin-Walled Radial Sheath for Large-Bore Access On Reducing Periprocedural Radial Artery Occlusion Following Complex PCI: The REDUCE-RAO Randomized Trial
Authors: Wang Hao , Wang Hao-Yu , Wu Shao-Yu , Yin Dong , Feng Lei , Song Wei-Hua , Wang Hong-Jian , Zhu Cheng-Gang , Dou Ke-Fei
Published: September 2022

Background: Transradial artery (TRA) access for percutaneous coronary intervention (PCI) was associated with lower risks of major bleeding and vascular complications compared to transfemoral artery access. Use of large-bore (≥7-Fr) guiding catheters through TRA approach increased the likelihood of radial artery occlusion (RAO). This study aimed to investigate whether use of the thin-walled 7-Fr Glidesheath Slender, allowing PCI with large-caliber guiding catheters, is superior to standard 7-Fr Cordis sheath with respect to periprocedural RAO within 24 hours after transradial coronary intervention (TRI) in complex lesions. Methods: A prospective randomized, controlled, single-blinded (patient-blinded) trial was conducted, randomizing 504 patients with TRI for complex lesions to either 7-Fr Glidesheath Slender or conventional 7-Fr Cordis sheath. The primary outcome was defined as the incidence of periprocedural RAO with Doppler ultrasound during the first 24 hours after TRI. Results: The incidence of early RAO was 10.3% for 7-Fr Glidesheath Slender and 13.5% for conventional 7-Fr sheath (p = 0.271). The procedural success rate for Glidesheath Slender was 92.9% and for Cordis sheath was 93.7% (p = 0.722). There was no signficiant difference between treatment arms in terms of local hematoma and radial spasm, whereas use of the Glidesheath Slender was associated with significantly less pain during the procedure (numeric rating scale [NRS], 2.27 ± 0.75 vs. 2.45 ± 0.95, p = 0.017). The assessment of radial artery in ultrasound parameters after complex TRI was improved with Glidesheath Slender. Conclusions: Among patients with complex coronary lesions undergoing TRI, 7-Fr Glidesheath Slender was not superior to conventional 7-Fr in the prevention of periprocedural RAO within 24 hours following complex PCI, without reducing RAO occurrence. Clinical Trial Registration: NCT04748068.
Examination of the Role of Family Socioeconomic Status and Parental Education in Predicting English as a Foreign Language Learners' Receptive Skills Performance
Authors: Suningsih Nining
Published: September 2022

There is a stereotype of a correlation between family socioeconomic status and parental educational background with the student's achievement. Therefore, this study aims to know in-depth roles. Examine 60 students of Melati Junior High School Samarinda in their performance on reading and listening comprehension tasks. There is a significant relationship between SES and parents' educational background using the correlational method, non-experimental. Nevertheless, it s not always that students with low socioeconomic and parents' educational backgrounds get low scores and vice versa. Likewise, students with high educational backgrounds of their parents do not necessarily get high grades in school. Several factors revealed that SES and Educational background is the main predictor of academic achievement.
Estimation of Genetic Superiority and Reproductive Performance of Dairy Cows at different rearing locations
Authors: Setyorini Yuliati Wahyu , Kurnianto Edy , Sutopo Sutopo , Sutiyono Sutiyono
Published: September 2022

The objective of this study was to estimate the genetic superiority using the estimated breeding value (EBV) and most probable producing ability (MPPA), and to elucidate the reproductive performance of dairy cows at different rearing locations. This study used data from dairy cows in two locations, namely at the breeding dairy center (Group I) for 100 heads and the smallholder farm (group II) for 40 head cows. The survey method was used in this study. The parameters observed were total milk production, days open (DO), service per conception (S/C), and calving interval (CI). The data were analyzed descriptively and using a t-test. The results showed that cows in group I had more superior genetic potential. Productivity in groups I and II for the total milk production were 5.017,52±1.096,84 and 3.922,52±1.296,55 kg/head/lactation, respectively;DO was 141,45±64,30 and 281,68±92,42 days, respectively S/C were1,47±0,61 and 1,70±0,69 times, respectively; and CI was421,59±63,47 and 565,23±95,33 days, respectively.  In conclusion, differences in management systems in breeding dairy centers and smallholder farms give different productivity. The results can be used for management improvement and increasing productivity strategies. Livestock selection can be done by estimating the genetic superiority using the estimated breeding value and most probable producing ability.
The Potency of Ammonia from Broiler’s Manure Based on Age Phase of Ration Administration on Closed House and Open House
Authors: Anggraini Mona , Badarina Irma , Brata Bieng
Published: September 2022

The aim of this research was to evaluate the potency of ammonia production from broiler’s manure based on the age phase of ration administration on the closed and open house cage. This research used Completely Randomized Design in Factorial 3x 2 with the first factor was three age phase of rations administration (0-10 days old, 11-21 days old and 22-32 days old) with three replications of each age phases. The second factor was the type of cage system (closed and open house) with two cages of each  cage type.  The variable observed was the ammonia concentration from broiler’s manure. The  Data were analyzed for their variance by Analyzes of Variance (Anova). The detailed test used Duncan Multiple Range Test.    The result of this research showed that the age phases of ration administration increased the manure ammonia concentration (P<0.05).  The older of age phase  increased the ammonia concentration.  The  cage system had significant effect to ammonia concentration.  The closed house system produced the ammonia concentration higher than open house cage.   The technology that were used in closed house system had a positive effect to ammonia mitigation.
Polymorphism of Prolactin Gene (PRL/PstI) In Sikumbang Jonti Duck Using PCR-RFLP Methods
Authors: Rafian Teguh , Yurnalis Yurnalis , Fenita Yosi , Iskandarsyah Rafi
Published: September 2022

This study is aimed to determine polymorphism of the Prolactin gene (PRL|PstI) in Sikumbang Jonti ducks using PCR-RFLP (Polymerase Chain Reaction–Restriction Fragment Length Polymorphism) method. This study used 56 Sikumbang Jonti ducks whose blood samples were taken. Gene amplification used a pair of primers forward 5' TGC AAA CCA TAA AAG AAA AGA 3' and reverse 5' CAA TGA AAA GTG GCA AAG CAA 3', which resulted in a 400 bp fragment in exon 5 of the Prolactin (PRL) gene. The amplification product was restricted using the PstI enzyme, which recognizes the truncation site (5' G↓ACGTC 3'). From 56 samples of Sikumbang Jonti ducks identified, just one genotype was found, homozygous (-/-) with only one allele (-). Analysis of the restriction product in Sikumbang Jonti ducks obtained a uniform genetic variation of PRL|PstI (monomorphic) with an allele frequency (-) of 100%.
Farmer Share and Efficiency of Breeding Cow Marketing Channels in Bali
Authors: Astiti Ni Made Ayu Gemuh Rasa , Rejeki I G. A. D. S. , Ngongo Marselina
Published: September 2022

Experts have widely carried out research on cattle since 1960. However, regarding the efficiency of the cattle marketing channel in Bali, especially in the livestock group in the village of Ayunan, it is necessary to study its efficiency for that researcher conducted research to know the efficiency of marketing cattle in Bali. Using the census method, 40 farmers consisted of two livestock groups, namely the Karang Ayu livestock group and the Karya livestock group, each consisting of 20 people. Instruments or measuring tools used in the interview guide to help obtain answers from respondents are structured and closed questionnaires for open-ended questions. The results showed four channels formed from the marketing system of cattle breeds in Bali, namely marketing channel i. Breeders sell livestock to other farmers in one village (12.5%), Marketing Channel ii. Breeders sell directly to animal markets (7.5%). %), Channel iii Farmers sell livestock to blank in the cattle barn (74.5%), and IV Farmers sell livestock to blank in the animal market (5.5%). With marketing efficiency for male seeds for each channel of 0; 2.57; 1.18, and 1.61, while the marketing efficiency in each channel for female cattle is: 0;3.53; 1.50, and 1.92. It is said that the most effective marketing channel for cattle breeds in Bali is through my marketing, namely the breeders selling the cow breeds in the stables and those who buy them around the farm because they do not incur marketing costs.
A Systematic Review of Cardiorespiratory Fitness Testing in Major Depression
Authors: Irvine Lachlan A. , Stanton Robert
Published: September 2022

Background

Depression is associated with physical inactivity, low cardiorespiratory fitness (CRF), and poor physical health compared with the general population. Various protocols are employed to determine CRF studies of people experiencing depression, but standardized methods are absent from the literature. Thus, the aim of the present review is to systematically examine the protocols reported to determine CRF in patients with major depressive disorder (MDD).

Methods

Replicating a previously published search strategy, the present review sourced relevant studies from PubMed, PsycInfo, Embase, CINAHL, MEDLINE, Psychology and Behavioural Sciences Collection, and SPORTDiscus from August 2015 to February 2021. Details of CRF testing protocols were extracted into a preprepared form for analysis.

Results

Twenty-three studies met the inclusion criteria, including those from a previous review of CRF in people with MDD. Twelve included studies employed maximal testing protocols, while 11 studies reported using submaximal testing protocols. Cycle ergometry was the most used protocol, followed by treadmill and walk tests. Notably, complete descriptions of the test protocols to facilitate test replication were frequently absent.

Conclusions

Cycle ergometry is commonly used to assess CRF in people with MDD, but protocol details are lacking, making replication difficult. Efforts to standardize protocol descriptions are warranted.
Imam Al-Ghazali dan Argumentasi Kosmologi tentang Tuhan
Authors: Ahmad Jumal
Published: September 2022

Menjelaskan tentang argumentasi Imam al-Ghazali tentang bukti keberadaan Tuhan dan premis-premisnya
THE HISTORY OF ALLAH
Authors: Obehetan Yeheskiel
Published: September 2022

Berdasarkan hasil resensi buku “The History Of Allah” yang ditulis oleh Bambang Noorsena maka saya mendapati hal-hal yang penting berkaitan dengan Apologetik Bambang Noorsena dalam mengklarifikasi kata “Allah” yang pada dewasa ini diklaim menjadi milik kaum/agama tertentu dan juga bagi mereka yang menolak untuk memakai nama atau kata Allah dalam kepercayaan mereka.
Differential expression of CRYL1 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: September 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines ALS using published and public data (3, 4). We found significant differential expression of CRYL1, encoding crystallin lambda 1, in the motor neurons of patients with ALS. CRYL1 was also differentially expressed in the induced pluripotent stem cell (iPSC)-derived motor neurons of patients with ALS. CRYL1 transcript was present at significantly higher levels in ALS patient motor neurons as compared to control motor neurons. These analyses will begin to define the transcriptional landscape of ALS.
Fresh Street Report_Sheffield
Authors: Relton Clare , Bridge Gemma , Crowder Mary , Blake Megan , Strong Mark , Roberts Gareth
Published: September 2022

Many people in the UK have diets low in fresh fruit and vegetables and high in energy-dense, nutrient-poor, processed foods. There are multiple drivers of poor diet including living in a food desert which is characterised by inadequate access to transportation and a limited a number of food retailers providing fresh produce, including fruit and vegetables, for affordable prices. Recent studies suggest that opening new independent retail outlets, such as farmers markets and produce stands can increase access to and consumption of fruit and vegetables in the short-term. In terms of improving affordability of healthier foods, mounting evidence indicates that price discounts and subsidies (including vouchers) can effectively increase the purchase and consumption of fruit and vegetables, especially when combined with nutritional information. Given the importance of fruit and vegetables for health, interventions that help increase fruit and vegetable intake are warranted. The aim of this project was to feasibility test ‘Fresh Street’, an area-based approach to creating sustainable and healthy diets, eating behaviours and food systems in areas of high deprivation. This project was carried out in Sheffield. The results of the feasibility project are described in the report.
Mutual Fund Allocations that Maximize Safe Portfolio Returns
Authors: Prendergast Michael
Published: September 2022

This paper describes an empirical analysis of optimized portfolios and safe return rates across multiple investment time horizons using Telser’s Safety-First method. The analysis uses thirty years of historical monthly data for 81 different Fidelity® mutual funds and a blended money market fund rate. The Fidelity® funds represent a wide variety of investment factors, strategies and asset types, including bonds, stocks, commodities and convertible securities. A large synthetic return dataset was generated from this data by a Monte-Carlo random walk using cointegrated bootstrapping of investment returns and yields. Portfolio optimization was then performed on this synthetic dataset for safety factors varying from 60% to 99% and time horizons varying from one month to ten years. Results from portfolio analyses include the following: 1) there are no risk-free investments available to Fidelity® mutual fund investors, as even money market funds have risk due to yield fluctuations, 2) optimized portfolios are sensitive to both investment time horizons and safety factor confidence levels, 3) conservative, short-term investors are better off leaving their money in a money market fund than investing in securities, 4) optimized portfolios for longer term, more aggressive investors consist of a blend of both value and growth equities, and 5) the funds most often represented in optimized portfolios are those that have the best risk/reward ratios, although this rule is not universal. Two practical applications of this optimization approach are also presented.
Negotiating Meaning Relationships in the Rhetorical Structure of EFL Argumentative Writing through Text Cohesion
Authors: Julianto Eko Amiadji
Published: September 2022

Being a configuration of logically interconnected statements realized in moves and stages, an argumentative essay is built around the notion of textual unity achieved through lexico-grammar and semantic associations. The study attempted to analyze the role of cohesion in the rhetorical structure of undergraduate EFL students. Hence, the 13 moves in the three-stage argument structure were analyzed on a preset framework of cohesion analysis. Discourse analysis as a research method was used to ascertain how cohesion functioned in the rhetorical structure of these argumentative essays. The results revealed the presence of cohesive associations between the different moves of the rhetorical structure which corresponded with the move length. Referential and Lexical cohesion had a more frequent and dense presence than the co-referential element in the sample texts; however, the relatively low incidence of conjunctives pointed towards the relative scarcity of rhetorical functions in students' writing. The study proposes a research initiative that could use frameworks other than the present study or compare two or more sub-genres for the use of cohesion in the rhetorical structure.
Differential expression of MIR646HG in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: September 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines sporadic ALS using published data (3, 4). We found significant differential expression of MIR646HG, encoding MIR646 host gene, in primary motor neurons of patients with ALS. MIR646HG was also differentially expressed in fibroblasts isolated from patients with ALS. MIR646HG transcript was present at significantly higher levels in ALS patient fibroblasts as compared to control, non-diseased fibroblasts. These analyses will begin to define the transcriptional landscape of ALS.
Al-Ghazali dan Tuduhan Kemunduran Sains Islam
Authors: Ahmad Jumal
Published: September 2022

Menjelaskan tentang tuduhan yang ditujukan kepada Imam al-Ghazali sebagai penyebab kemunduran sains dunia Islam dan bantahannya.
KONSEP DASAR DAN RANCANG BANGUN EKONOMI MIKRO ISLAM
Authors: Irwan Arfin Muh.
Published: September 2022

Ekonomi di perkenalkan pertama kali oleh ahli filsafat yanh berasal daru yunani yang nernama Xenophone, yang terdiri dari kata oikos yang berarti keluarga atau rumah tangga dan Nanios yang berarti peraturan aturan dan hukum Permasalahan Ekonomi Mikro. Dengan demikian, secara sederhana ekonomi dapat diartikan secara sederhana ssenagai kaidah kaidah,aturan, cara pengelolaan rumah tangga.Dapat diartikan secara luar ilmu ekonomi merupakan ilmu yang mempelajari perilaku individu dan masyarakat yang kebutuhannya tidak terbatas, sedangkan alat pemuas kebutuhannya tidak terbatas.Ekonomi mikro islam merupakan bagaimana sebuah putusan diambil oleh tiap ekonomi dengan memasukkan batasan batasan syariah sebagai variabel utama.
Special Needs Elementary Schools' Clinical Supervision In Indonesia
Authors: Sihombing Wingston L , Manurung Nurliani
Published: September 2022

The relevance and challenges of clinical supervision for effective teaching and learning in Elementary schools with special needs exploring through descriptive survey research. We collected data using twenty questionnaire items from 429 respondents consisting of principals and teachers and analyzed them using t-test statistics. The research findings reveal several relevancies of clinical supervision in teaching and learning: improving teacher classroom behavior and supporting students' clinical learning. Clinical management has challenges, including disagreements on collaboration between teachers and principals, lack of trained supervisors, inadequate supervisors in various areas of specialization, and time constraints. Based on these findings, this study recommends that the Management Board of elementary schools with special needs requires clinical supervision at least once a month.
Empirical Study of Elite Networks with Wikidata
Authors: Yalcin Omer Faruk
Published: September 2022

The elusiveness of cross-country empirical measurement is a significant hurdle in the study of comparative political elite networks. Most studies of elites focus on a few countries or a region, limit their scope to specific institutions, and use ad-hoc data collection methods, making comparative work difficult. Wikidata stores not only entities like people, places, and institutions but also the relationships that connect them, such as parent, alma mater, country of citizenship, and so on.Wikidata's bias toward notable people and its graph structure make it suitable for elite networks. An application to kinship networks with data on 272,930 actors across the globe shows that kinship ties among the elite increase with authoritarianism, conforming to theories of coup-proofing and corruption.
Early maladaptive schemas and mental disorders in adulthood: A systematic review and meta-analysis
Authors: Thimm Jens C
Published: September 2022

Early maladaptive schemas (EMSs) are broad and pervasive themes regarding oneself and one’ relationships with others originating from adverse childhood experiences. Although the concept of EMSs was initially developed for the treatment of personality disorders, the associations of EMSs with a variety of other mental disorders have been investigated. The goal of the present study was to summarize and analyze the EMSs-disorder associations in studies in which patients with specific psychiatric diagnoses were compared to healthy controls. Of the 28 studies that met the inclusion criteria, 27 were included in a meta-analysis. Across diagnoses, all EMSs were elevated in the clinical groups. The largest effect sizes were observed for the social isolation, the negativity/pessimism, the defectiveness/shame and social undesirability schemas. Depression (n=8), borderline personality disorder (n=5), and obsessive-compulsive disorder (n=5) were the most frequently studied mental disorders. Heterogeneity between studies was high. Results suggest that mental disorders are not characterized by specific EMSs.
A Digital Single-Session Intervention Platform for Youth Mental Health: Cultural Adaptation, Evaluation, and Dissemination
Authors: Shroff Akash , Roulston Chantelle A , Fassler Julia , Dierschke Nicole A. , San Pedro Todd Jennifer , Rios Ámbar , Plastino Kristen , Schleider Jessica L.
Published: September 2022

BACKGROUND. Despite the proliferation of evidence-based digital mental health programs for young people, low uptake and inconsistent implementation precludes them from benefiting youth at scale. Identifying effective implementation strategies for evidence-based supports is especially critical in regions where treatment access is lowest due to mental health provider shortages. Objective. The goal of this academic-community partnership, funded by the City of San Antonio Metropolitan Health District, was to culturally adapt, disseminate, and gauge the acceptability and utility of an evidence-based digital mental health platform—Project YES (www.schleiderlab.org/yes)—among English- and Spanish-speaking youth living in south Texas. METHODS. Project YES is an open-access, anonymous platform containing three evidence-based, self-guided interventions for youth mental health. Project YES was culturally adapted via focus groups and co-design sessions with San Antonio youth with lived experience of depression and anxiety; translated into Spanish; and disseminated throughout San Antonio, Texas, via community and school partnerships. RESULTS. During the project period (April 2021–December 2021), 1,801 San Antonio youth began and 894 completed a 30-minute, single-session intervention within Project YES (ages 11-17; 39.9% male, 53.4% female, 0.2% intersex; 82.0% Hispanic, 4.3% non-Hispanic white, 6.3% Black, 1.6% Asian, 5.2% other). This completion rate (49.6%) surpassed those previously observed for Project YES (e.g., 34% when disseminated via social media). San Antonio youth rated Project YES as highly acceptable across all metrics, both in English and Spanish. Additionally, youth who completed Project YES - ENGLISH reported significant improvements in hopelessness (d = 0.33), self-hate (d = 0.27), and perceived agency (d = 0.25), from pre- to post-intervention, and teens who completed Project YES - SPANISH reported improvements in self-hate (d = 0.37) from pre- to post-intervention. CONCLUSIONS. Results indicate that Project YES—an open-access, free, anonymous online single-session intervention (SSI) platform—is an acceptable, accessible, and applicable mental health support for English- and Spanish-speaking San Antonio youth.
Automated content analysis of cultural diversity perspectives in annual reports (DivPAR): Development, validation, and future research agenda.
Authors: Hofhuis Joep , Schafraad Pytrik , Trilling Damian , Luca Nastasia , van Manen Bastiaan
Published: September 2022

Objectives: In this paper, we present a digital tool (DivPAR) for automated content analysis of annual reports, designed to identify the presence of three cultural diversity perspectives – the Moral, Market, and Innovation perspectives - based on earlier work by Ely and Thomas (2001). Methods: In Study 1, we describe the development and validation of the instrument, through an iterative procedure in which manual annotation of independent subsamples (n = 24, 25) by human coders was compared to the computer coding in subsequent rounds, until sufficient agreement was reached. In study 2, we illustrate the type of data that the script generates, by analyzing the prevalence of the three perspectives in annual reports of 55 Dutch organizations over a period of two decades (1999-2018; n = 937). Results: Our findings confirm that DivPAR is sufficiently reliable for use in future research. In study 2, we show that among Dutch organizations, the moral perspective is most prevalent, but the market and innovation perspective are increasing in popularity. Conclusions: DivPAR can be used to analyze the prevalence and longitudinal development of diversity perspectives in organizational communication. It enables scholars to draw comparisons across different sectors, regions or countries, to study how diversity perspectives correlate with societal developments, and to uncover the (lack of) relationships between diversity communication and diversity outcomes. Directions for future research are discussed at the end of the paper.
Wrinkles in subsecond time perception are synchronized to the heart
Authors: Sadeghi Saeedeh , Wittmann Marc , De Rosa Eve , Anderson Adam K.
Published: September 2022

The role of the heart in the experience of time has been long theorized but empirical evidence is scarce. Here we examined the interaction between fine-grained cardiac dynamics and the momentary experience of subsecond intervals. Participants performed a temporal bisection task for brief tones (80-188 ms) synchronized with the heart. We developed a cardiac Drift-Diffusion Model (cDDM) that embedded contemporaneous heart rate dynamics into the temporal decision model. Results revealed the existence of temporal wrinkles — dilation or contraction of short intervals — in synchrony with cardiac dynamics. A lower pre-stimulus heart rate was associated with an initial bias in encoding the millisecond-level stimulus duration as longer, consistent with facilitation of sensory intake. Concurrently, a higher pre-stimulus heart rate aided more consistent and faster temporal judgments through more efficient evidence accumulation. Additionally, a higher speed of post-stimulus cardiac deceleration, a bodily marker of attention, was associated with a greater accumulation of sensory temporal evidence in the cDDM. These findings suggest a unique role of cardiac dynamics in the momentary experience of time. Our cDDM framework opens a new methodological avenue for investigating the role of the heart in time perception and perceptual judgment.
Experience of typical variations in stressors impact hippocampal structure and functional connectivity in childhood
Authors: Botdorf Morgan , Riggins Tracy
Published: September 2022

Abuse and maltreatment have been shown to negatively impact the developing brain through the HPA-axis, the body’s central stress response system. Theoretically, similar pathophysiology occurs when children experience more moderate forms of stress (i.e., changing schools); however, evidence for this association is lacking. To address this question, the current study explored the effects of typical variations in stressful events on the development of the hippocampus, a brain region susceptible to stress. Data from a 3-year accelerated longitudinal sample of 79 4- and 6-year-old children were used to assess the impact of stressful events on the development of hippocampal subfield volumes and functional connectivity. In the 4-year-old cohort, stressful experiences were related to increased functional connectivity between the hippocampus and the insula, a region important for emotional processing. In the 6-year-old cohort, stressful experiences were related to smaller CA1 and CA2-4/DG subfield volumes. Results from analyses comparing cohorts showed that there was a significantly greater effect of stressful events on CA2-4/DG volume in 6- compared to 4-year-old children. Overall, these findings provide evidence of the impact of typical variations in stressful events on the structure and function of the hippocampus and highlight the region and time-dependent nature of these stress effects. They also highlight the importance of understanding how brain development is impacted by stress in all forms because stress-related alterations in hippocampal development have been linked to variations in cognitive processes (e.g., memory) and risk for psychopathology (e.g., major depressive disorder).