bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of prognostic factors in lung cancers with surgical complete response after induction treatment
Authors: Vedat Doğru Mustafa , Buğra Sezen Celal , Aker Cemal , Erdoğu Volkan , Saydam Özkan , Ölçmen Aysun , Cansever Levent , Metin Muzaffer
Published: June 2021

Background: This study aims to evaluate long-term results of induction treatment and to investigate prognostic factors affecting survival in non-small cell lung cancer patients with a pathological complete response.

Methods: Between January 2010 and December 2017, a total of 39 patients (38 males, 1 female; mean age: 56.2±8.3 years; range, 38 to 77 years) having locally advanced (IIIA-IIIB) non-small cell lung cancer who were given induction treatment and underwent surgery after induction treatment and had a pathological complete response were retrospectively analyzed. Survival rates of the patients and prognostic factors of survival were analyzed.

Results: Clinical staging before induction treatment revealed Stage IIB, IIIA, and IIIB disease in three (7.7%), 26 (66.7%), and 10 (25.6%) patients, respectively. The five-year overall survival rate was 61.2%, and the disease-free survival rate was 55.1%. In nine (23.1%) patients, local and distant recurrences were detected in the postoperative period.

Conclusion: In patients with locally advanced non-small cell lung cancer undergoing surgery after induction treatment, the rates of pathological complete response are at considerable levels. In these patients, the five-year overall survival is quite satisfactory and the most important prognostic factor affecting overall survival is the presence of single-station N2.
Is arterial switch operation possible with neonatology-focused intensive care unit modality
Authors: Doyurgan Onur , Özdemir Fatih , Akdeniz Osman , Kuddusi İrdem Ahmet , Matur Okur Nilüfer , Salık Fikret , Aldudak Bedri
Published: June 2021

Background: In this study, we aimed to examine the feasibility of arterial switch operation and its perioperative management with neonatology-focused intensive care modality in a region of Turkey where the birth rate and the number of asylum seekers who had to leave their country due to regional conflicts are high.

Methods: Between December 2017 and June 2020, a total of 57 patients (48 males, 9 females; median age: 12.2 days; range, 2 to 50 days) who were diagnosed with transposition of the great arteries in our clinic and underwent arterial switch operation were retrospectively analyzed. All patients were followed by the neonatologist in the neonatal intensive care unit during the preoperative and postoperative period.

Results: Thirty-eight (66.7%) patients had intact ventricular septum, 16 (28.1%) had ventricular septal defect, two (3.5%) had coarctation of the aorta, and one (1.7%) had Taussig-Bing anomaly. Coronary artery anomaly was present in 14 (24.5%) patients. The most common complications in the intensive care unit were renal failure requiring peritoneal dialysis in seven (12.3%) patients, supraventricular tachyarrhythmia in six (10.5%) patients, and eight (14%) patients left their chests open. The median length of stay in intensive care unit was 13.8 (range, 9 to 25) days and the median length of hospital stay was 24.5 (range, 16 to 47) days. The overall mortality rate for all patients was 12.3% (n=7). The median follow-up was 8.2 months. A pulmonary valve peak Doppler gradient of ≥36 mmHg was detected in five patients (8.7%) who were followed, and these patients were monitored by providing medical treatment. None of the patients needed reoperation or reintervention.

Conclusion: We believe that arterial switch operation, one of the complex neonatal cardiac surgery, can be performed with an acceptable mortality and morbidity rate with the use of neonatology-focused intensive care modality, which is supported by pediatric cardiology and pediatric cardiac surgery.
Failed carotid artery stenting followed by successful surgical intervention: Case report
Authors: Govedarski Valentin , Dimitrova Elitsa , Vassileva Zornitsa , Dimitrov Svetoslav , Iovev Svetoslav
Published: June 2021

A 56-year-old female patient with significant carotid stenoses with circumferential plaques, causing localized vascular narrowing, was inappropriately indicated for carotid artery stenting. After placement of a distal embolic protection device in the left internal carotid artery, a stent was inserted; however, it could not be fully deployed due to the rigid, severely calcified vascular walls. The various endovascular attempts to recapture the protection device were futile and, eventually, led to fracture of the guidewire of the device and it remained entrapped together with the stent. Emergency carotid arteriotomy with extirpation of the stent and embolic protection device via carotid thromboendarterectomy was performed. In conclusion, the proper patient selection for carotid artery stenting is of utmost importance.
Study on Motorcycle Crash Cost in Bandung City
Authors: Pangestika Safety Husna , Kusumawati Aine , Sjafruddin Ade
Published: June 2021

Crash cost is an important component for conducting economic analysis in selecting countermeasures for crash locations. It is used to convert the benefit of crash or fatality reduction into monetary terms. Many research on crash cost have been carried out in Indonesia. Most of the research utilized gross output/human capital approach. However, this approach has been widely criticized for not being able to describe the quality of life of crash casualties and the costs of pain, grief and suffering (i.e. human cost). The concept of Value of Statistical Life  (VoSL) has been introduced by InDeV (2016) to calculate the human cost, which is assessed by using willingness to pay approach. To obtain a more reliable estimation of crash cost for Indonesia, it is necessary to conduct a study on crash cost involving motorcycles which incorporates the estimation of human cost. The VoSL is obtained by interviewing motorcycle users for willingness to pay with safety equipment. Based on the analysis, it is obtained that the value of statistical life (VoSL) for fatality in a road crash was estimated to be Rp.2.3 billion. The unit cost of fatal injury is Rp.3.08 billion, serious injury is Rp.333 million and slight injury is Rp.24.9 million. The unit cost of fatal crash on arterial roads is Rp.3.23 billion, serious crash is Rp.451 million and the slight crash is Rp.114 million. The unit cost of fatal crash on collector roads is Rp.3.16 billion, serious crashes is Rp.381 million and minor crash is Rp.69.4 million. The unit cost of fatal crash on local roads is Rp.3.09 billion, serious crash is Rp.338 million, and minor crash is Rp.29.8 million.
Keywords: Motorcycle crash cost, gross output approach, human capital approach, willingness to pay approach
EFEK ANGKUTAN SEDIMEN BED-LOAD TERHADAP HAMBATAN ALIRAN DI SUNGAI BATURUSA PULAU BANGKA
Authors: Maini Miskar , Mashuri Mashuri , Susanti Junita Eka
Published: June 2021

Angkutan sedimen pada sungai alami tentunya memberikan dampak terhadap karakteristik pengalirannya. dampak adanya proses transpor sedimen tentu akan berpengaruh terhadap debit aliran yang terjadi di sungai. Debit aliran berpengaruh terhadap parameter hidraulik, kemiringan dan nilai hambatan yaitu kekasaran dasar sungai. Adapun tujuan yang ingin dicapai dari studi ini adalah menganalisa efek material angkutan sedimen bed-load terhadap hambatan aliran atau koefisien kekasaran. Penelitian ini dilakukan di 10 (sepuluh) cross section pada Sungai Baturusa dengan pengambilan sampel bed-load di dasar sungai dan dilakukan pengujian gradasi ukuran butiran partikel sampel material bed-load sedangkan parameter kecepatan aliran diukur menggunakan Propeller Currentmeter dan diukur juga dengan metode pelampung dalam pengukuran kecepatan permukaan dengan faktor koreksi 0,85. Hasil analisis koefisien hambatan dengan angkutan sedimen (bed-load) menunjukkan nilai koefisien hambatan lebih besar dibandingkan tanpa angkutan sedimen (no bed-load), angkutan sedimen yang terjadi di Sungai Baturusa akan mempengaruhi nilai koefisien hambatan aliran. Sedangkan analisa debit aliran berdasarkan koefisien Manning yang digunakan beberapa metode semuanya memberikan selisih debit yang sangat besar terhadap debit terukur, penentuan nilai Manning memiliki pengaruh yang cukup besar dalam estimasi kecepatan aliran dan debit aliran., selain itu kecepatan aliran, pengaruh Fr dan U/U* juga memiliki pengaruh terhadap nilai koefisien kekasaran pada Sungai Baturusa.
Mitarbeiterbindung im öffentlichen Dienst
Authors: Schulte Susanne , Pinger Gina
Published: June 2021

Der Fachkräftemangel führt auch im öffentlichen Dienst zu Überlegungen, die Attraktivität der eigenen Arbeitsplätze mehr in den Fokus zu rücken, um Mitarbeitende verstärkt für sich zu interessieren und an sich zu binden.

Obwohl der öffentliche Dienst in vielerlei Hinsicht ein vorbildlicher Arbeitgeber ist, tut er sich schwer, dies umfänglich zu zeigen. Wirbt er beispielsweise mit Familienfreundlichkeit wie auch andere Arbeitgeber, verblassen die faktischen Vorteile, die hinter dem Attribut "familienfreundlich" stehen. Leistungen im Gießkannenprinzip mögen gerecht und auch teuer sein, erreichen jedoch trotzdem nicht jeden Mitarbeiter. Dies und viele weitere spannende Erkenntnisse werden in den einzelnen Kapiteln dieses Buches diskutiert und mögliche Umsetzungen vorgeschlagen.

Dieses Buch stellt die Grundlagen für die Mitarbeiterbindung im Überblick dar und arbeitet die Vorteile öffentlicher Arbeitgeber heraus, damit sie aktiv bei potenziellen und aktuellen Mitarbeitern beworben werden können. Es beschreibt verschiedene Instrumente der Mitarbeiterbindung und gibt Anregungen für die praktische Umsetzung. Letztlich werden die Umsetzungen einiger öffentlicher Arbeitgeber als Best Practice vorgestellt.

Dr. Susanne Schulte ist Diplom-Psychologin und Professorin für Wirtschaftspsychologie, insbesondere Arbeits-, Personal- und Organisationspsychologie an der Hochschule Fresenius für Wirtschaft & Medien GmbH.

Gina Pinger ist nach ihrem Abschluss als Bachelor of Laws im Bewerbercenter im Bereich der internen Stellenbesetzungsverfahren für die technischen Ämter bei der Stadt Köln tätig.
Transzendentalphilosophie als kritische Bestimmung des Stand­punkts. Eine wissenschaftstheoretische Annäherung
Authors: Meer Rudolf
Published: June 2021

Both the categories and principles of understanding as well as the ideas and principles of reason build transcendental elements to conceive transcendental philosophy as a philosophical system. Accordingly, in addition to the “Transcendental Analytic”, Kant develops in the “Transcendental Dialectic” an expanded concept of the transcendental. The transcendental ideas do not denote object-constitutive principles but, in a weaker sense, conditions of the possibility of experience. The relation between Division One and Division Two of the “Doctrine of Elements” can be demonstrated exemplarily with regard to Kant’s references to astronomy. Based on the constitutive principles of understanding, which are directed towards the field of possible experience and provide a connection of cognition through reasons and consequences, as well as the regulative principles of reason, which form maxims of research, astronomy is a proper and rational natural science. The analysis of the case studies of astronomy shows that Kant uses the term transcendental within the framework of the “Transcendental Logic” of the Critique of Pure Reason to denote conditions that are constitutive for the possibility of an object in general and for describing necessary regulative conditions of experience. With these reflections, Kant places his transcendental philosophy in a long tradition of philosophical thought in which the celestial bodies are the preferred subject.
Optimizing the mutual arrangement of pilot indicators on an aircraft dashboard and analysis of this procedure from the viewpoint of quantum representations
Authors: Kuravsky Lev , Greshnikov Ivan
Published: June 2021

The purpose of this work is to present the first attempt to provide quantitative analysis and objective justification for designers' decisions that relate to the arrangement of pilot indicators on an aircraft dashboard with the use of video oculography measurements. To date, such decisions have been made only based on the practical experience accumulated by designers and subjective expert assessments. A new method for optimizing the mutual arrangement of the dashboard indicators is under consideration. This is based on iterative correction of the gaze transition probability matrix between the selected zones of attention, to minimize the difference between the stationary distribution of relative frequencies of gaze that are staying in these zones and the corresponding desirable target eye movements that are given for distribution for qualified pilots. When solving the subsequent multidimensional scaling problem, the gaze transition probability matrix that is obtained is considered to be the similarity matrix, the elements of which quantitatively characterize the proximity between the zones of attention. The main findings of this novel work are as follows: the use of oculography data to justify dashboard design decisions, the optimizing method itself, and its mathematical components, as well as analysis of the optimization in question from the viewpoint of quantum representations, all revealed design mistakes. The results that were obtained can be applied for prototyping variants of aircraft dashboards by rearranging the display areas associated with the corresponding zones of attention.
A Cruising Boat
Authors: Curtze Charles A.
Published: June 2021

The paper discusses the trade-offs and pay-offs of designing and building big ship capability into a small cruising sailing yacht. A norwegian resuce ship hull form, large three bladed controllable pitch propeller, nickel cadmium batteries, shaft driven generator, above average horsepower, a high degree of watertight integrity, modest self-salvage capability, tug boat handling under power, low helmsman energy drain under all conditions, circumferential safety and grab rail, balanced rudder, diesel oil fired range, hot water central heating are discussed as they combine to fill the author's requirements for seaworthiness, seakeeping ability, safety, maintainability, self sufficiency and comfort at sea.
Vane Self-Steerers for Cruising Yachts
Authors: Ratcliffe Gererd
Published: June 2021

This paper presents some of the things the designer or purchaser of a cruising yacht should keep in mind when vane actuated self-steering is to be installed. First, the characteristics of various types of rudders, pendulum-fins, trim-tabs, and wind vanes are compared. These components are then linked to form different types of self-steerers. These are the simple vane steerers, trim-tab steerers, and pendulum-fin steerers. The auxiliary rudder is a special type of trim-tab steerer.

The linkage between the wind-vane and the trim-tab of fin is design to make the most efficient use of the main active components, and to stabilize the control. Basic feedback theory is applied to yacht steering to show the relationship between all of the factors that determine the heading. Some of the basic requirements for self-steering: sensitivity, adequate power, and system "stiffness" are briefly analyzed, and the degree to which these requirements can be met by the different self-steering system is compared.

Several examples are used to show how technical and dimensional factors, such as hull shape, rudder location, and clearance for the wind vane, determine the type of self-steering gear most suitable for a particular boat. In addition, the intended use, whether for a single handed crossing or occasional week-end trips, may be an important factor, especially if the installation is complex and expensive.
Extended Cruising - An Overview
Authors: Court Kenneth E.
Published: June 2021

The author discusses some ideas about cruising yachts and cruising yachtsmen and the preparations and paraphernalia necessary for extended cruising. His purpose is to illustrate how simple it can be to embark on a successful voyage provided one has a good boat, the right temperament, a fair degree of seamanship, and a minimum of sophisticated gear. These observations are based on personal experience including a four-year cruise from Hawaii to the Chesapeake via the Red Sea.
Formal incentive systems in organization with a Swedish management style: conflict or interaction?
Authors: Cäker Mikael , Andersson Thomas , Wickelgren Mikael
Published: June 2021

The aim of our study is to explore how organizations that are typically characterized as under a Swedish management style relate to the trend of increased use of formal incentive systems. Interview-based case studies of two organizations with management principles strongly rooted in Swedish culture. Both organizations operate in industries strongly influenced by external pressure, which includes the discourse of incentive systems as a modern feature of management.Our results point at companies under a Swedish management systems recoqnizes the intrustion of incentive systems, but try to align with their own ideas about management as far as possible. A broad perspective on employee motivation, with a focus on career planning and development take a central role. On a strategic level, these organization tries avoid conflicts between the ideas of incentive systems and their existing management ideas in everyday management activity, by taking an explicit stand on a high organizational level.Further consideration of how incentive systems aligns with existing management ideas is needed. The well documented negative effects of incentive systems on employee relations can be avoided through active choices concerning how to implement incentive systems. Contributes to our understanding of how ideas of incentive systems interact with management  ideas that builds on trust and open communication.
Getting out of mechanical management: lessons from Chinese thought
Authors: Ancelin-Bourguignon Annick
Published: June 2021

Most management models draw on a mechanical view of organizational action, in which outcomes are given a prominent role, at the detriment of persons. These are generally viewed as instruments serving action and its objectives. As a result work is increasingly losing sense for a number of employees whatever their hierarchical position. Ill-being at work is developing to the extent than managing so-called ‘psychosocial risks’ has become a new branch of human resource management. Simultaneously meaninglessness hinders creativity at work and beyond, performance. Mechanical management is thus detrimental to both individuals and organizations – hence there is an urgent need to address this question.The objective of this paper is to explore new ways of thinking by which management could avoid the ineluctable consequences of mechanical management. This is an analytical paper which draws upon a variety of contributions in management, psychology and philosophy. In the first Part I will recall the process through which mechanical management is detrimental to both organizational members and organizations, as well as present some proposals by work psychologists to loosen the knot by which mechanical management, which is supposed to be beneficial to organizations and individuals, is actually detrimental to them. Although psychologists open up fertile paths to renew management, their responses only address some aspects of the problem and may fail to change organizational practices in depth. I believe management needs to be questioned both more globally and more deeply.To this end, I will turn out to philosophy to show, in the second Part, that mechanical management is a direct expression of Ancient Greece thought, which can be considered as the matrix of conceptions of action, world and time that have inspired all Western thoughts and realizations since then – and in particular, management. To break with mechanical management, Part Three will then offer views on Chinese thought - which provides radically different perspectives on action, time and the world and thus can open up innovative paths for thinking new forms of management. The conclusion will discuss the contribution, limits and academic implications of this analysis.
Highlighting the complex interrelationship between the concepts of trust and control
Authors: Beusch Peter
Published: June 2021

This paper presents the area of management control and trust in an inter-organizational setting with an attempt to offer a fresh perspective on the complex relationship between and different understandings of the two concepts of trust and control. This is done with help of two case studies in a cross-cultural setting and involving five multinational companies that were involved in two large acquisitions. Obviously, different actor groups’ cultural and educational heritage has brought with it that dissimilar opinions exist on the subject of mainly system-based versus inter-personal based trust.The paper first demonstrates that trust and control can mean different but also the same things to different people, depending very much on the logic and values applied but also depending on if the actors were motivated more intrinsically or extrinsically. Further, what impact certain control mechanisms, or the lack thereof, have on individual’s behavior is outlined. The paper also reveals that it is difficult to find the right balance between diverse types of control and trust as time went on after the acquisitions. The main reason for this is that actors with different socio-cultural heritage use different references regarding trust and control and put unlike emphasis on what should be focused on, what should be counted, and what should be accounted for. Trust and control can mean almost identical things but the cases illustrate that, from a rhetorical and convincing point of view, system trust appears to be stronger in certain settings than inter-personal trust, as it, to particular actors, provides the impression of being in control. The contrary is true in other settings, where having ‘facts and figures’ and ‘a whole bunch ‘of accounting systems and accounting techniques not automatically mean to be in control, thus leaving more room for the use and appreciation of inter-personal trust.
Are you sure about what you mean by ‘uncertainty’? The actor’s perspective vs. the institutional perspective
Authors: Borisov Boris Genadiev , Lueg Rainer
Published: June 2021

This paper explicates theoretical and methodological differences between Archival Environmental Uncertainty (AEU) and Perceived Environmental Uncertainty (PEU). Conceptually, we discuss the controversial development of the concepts in a literature review. We propose a reconciling framework which emphasizes that AEU and PEU differ due to the specificity of the decision unit, the predictability of change, and the use of leading indicators. We conclude that future conceptual work could further refine AEU- and PEU-measures; especially a better distinction between AEU and ‘risk’ is warranted.Empirically, we are the first ones to investigate the statistical association between prevailing measures of AEU (Tosi et al., 1973; Dess and Beard, 1984) and PEU (Miller, 1993). Our analysis combines archival data on AEU (annual reports) with survey data on PEU from top executives of the 110 largest listed German companies (55% response rate) by using time series-, factor- and correlation-analyses. Our findings show—as predicted—that AEU and PEU correlate moderately on a significant level. Yet, adjustment of the AEU-measure for predictable changes does not increase the strength of this correlation. This implies that future empirical work should focus more on the specificity of the decision unit and the use of leading indicators than on adjusting the predictability of change
The outsourcing decision-making process: two extensions to the management accounting toolkit
Authors: Nielsen Lars Bråd , Nørreklit Hanne
Published: June 2021

In response to a lack of research, this paper explores the type of reasoning that companies use to structure their complex outsourcing decision and the procedures for producing relevant accounting information. Analyzing two manufacturing companies, we uncover two methods for structuring the outsourcing decision-making process and for determining relevant accounting information: an analytical method and an actor-based method rooted in pragmatic constructivism. The two cases show that both strategy and management accounting play an interrelated, crucial role in the decision to outsource. The article adds to the academic literature on calculative decision theory by accentuating the notion of ‘practice’ rational decision-making, where managers have to integrate sensing and reasoning into practical affairs. In practice, the results provide extensions to the management accounting toolkit since these cases can serve as inspiration for structuring the outsourcing decision-making process in similar situations.
Reality as a construct: outline of a pragmatic constructivist perspective
Authors: Nørreklit Lennart
Published: June 2021

Consider the idea that reality is a construct. Are constructivist and realist perspectives not incompatible? Well, they are often construed as more or less incompatible and competing perspectives: Constructivism being mainly considered a subjectivist and idealistic perspective while the opposite perspective, realism, is considered an objectivist or materialist perspective. However, the ordinary usage of the terms ‘reality’ and ‘construction’ discloses no contradiction but a group of nicely interrelated concepts.
Further explorations of possibilities, methodologies of the future and rogue traders
Authors: Jack Lisa
Published: June 2021

This presentation continues the discussion begun in May 2014 on the use of pragmatic constructivism and the actor reality construction framework in the analysis of financial crime.  Here, I examine one aspect, which is the use of the work of Barbara Adam on actors’ concepts of future time to develop an empirical framework for researching possibilities.  This is applicable to any empirical study using actor reality perspectives, but I am particularly interested in how rogue traders and their employers envisage and act on the possibilities open to them.
The role of stakeholders in relation to the business model in the taxi industry
Authors: Bitsch Jakob , Brochstedt Sara , Holm Alexander Hjerrild , Knudsen Andreas
Published: June 2021

This paper illustrates how business models and business model innovation are related to the theory of stakeholders. Thepaper explores how lack of business model innovation in the taxi industry, can be explained by the relation to the powerand interests of its stakeholders. The authors have employed an explanatory case study, using multiple sources ofevidence, primarily archival records and observations. The research reveals that the business model of the taxi industryhave not experienced major changes, even though the environment surrounding the taxi industry have seen severalchanges. An analysis of the stakeholders of the taxi industry explains that the lack of business model innovation is aconsequence of the misfit between the power of the taxi industry and government, and the customers. The papercontributes to the existing literature of business models, business model innovation and stakeholder theory, and theirrelation in between.
The role of management accounting in the construction of the new generation leadership in family firms: An Actor- Reality perspective
Authors: Leotta Antonio , Rizza Carmela , Ruggeri Daniela
Published: June 2021

Succession in family firms may determine the survival or the failure of the business itself. Management accountingliterature has added little to this issue, mainly focusing on the process of succession and change (Songini et. al, 2013;Giovannoni et al., 2011). The present study deals with new management accounting (MA) practices that the juniorgeneration may introduce during the process of succession. The aim of the study is to show that the introduction of newMA practices can contribute to construct the leadership profile of the junior generation. Drawing on the perspective ofActor-Reality Construction, we conducted a case study at a small-sized, family firm producing solar shading systems.We examined how the process of succession derives from the integration of four dimensions of reality: facts,possibilities, values and communication. Such an integration is facilitated by the introduction of a new accountinginformation system and cost report. The case evidence highlights that the construction of the new generation leadershipmay emerge as unintended consequence of the introduction of new MA practices. From the emergent perspective ofActor-Reality Construction, the paper investigates the role of new management accounting practices in the actor-worldrelation constructing the new generation leadership.
Expérience amoureuse la plus difficile : Qu’en disent les garçons rapportant un vécu de violence physique dans leurs relations amoureuses ?
Authors: Lafrenaye-Dugas Anne-Julie , Fernet Mylène , Hébert Martine , Blais Martin , Godbout Natacha
Published: June 2021

Objectifs : Bien que la majorité des écrits portant sur la violence physique dans les relations amoureuses (VRA physique) s’attardent à la victimisation chez les filles, les garçons sont également à risque. Cette étude vise à documenter les expériences amoureuses de garçons ayant vécu de la VRA physique.Méthode : Dans l’Enquête Parcours Amoureux des Jeunes, 1 701 garçons ont rapporté avoir eu une relation amoureuse dans la dernière année. Parmi eux, 184 ont subi au moins un épisode de VRA physique et ont répondu à une question ouverte les invitant à décrire l’expérience la plus difficile vécue dans une relation amoureuse. Une analyse qualitative a été réalisée à partir des réponses, puis a été complétée avec des analyses corrélationnelles et de comparaison de moyennes.Résultats : Cinq catégories conceptuelles ont émergé, relatant des difficultés relationnelles (n = 39) ou sexuelles (n = 9), des ruptures amoureuses (n = 47), des expériences d’infidélité (n = 57) ou de VRA (n = 19). Treize participants ne rapportaient aucun événement difficile. Seulement 15 participants ont évoqué un événement de VRA, et trois de VRA physique subie. Les analyses révèlent que plus un participant rapporte une tolérance élevée envers la violence, plus il a vécu de formes différentes de VRA.Implications : Les témoignages recueillis soulignent la présence de plusieurs sources de détresse dans leurs relations amoureuses, cumulés à la VRA physique. Ces constats soulèvent l’importance d’aider les garçons à développer leurs capacités de résilience et à reconnaître les différentes formes de VRA, et de les soutenir dans leur recherche d’aide.
The Use of Mobile Applications to Support Indigenous Youth Wellbeing in Canada
Authors: Noronha Noella , Smith Savanah J. , Martin Hill Dawn , Davis Hill Lori , Smith Sara , General Amy , McQueen Cynthia , Looking Horse Makaśa , Drossos Alexander , Lokker Cynthia , Bilodeau Nicole M. , Wekerle Christine
Published: June 2021

In Canada, Indigenous youth have remained resilient despite being confronted with a wide range of structural and systemic risks, such as long-lasting boil water advisories, over-representation in the child welfare system, and injustices related to land treaties. As people of the land, all disruptions to ecological health are a disruption to personal and community holistic health. Land-based activities and cultural continuity strengthen pathways of perseverance for Indigenous youth (Toombs et al., 2016). For youth, cultural self-expression and personal agency are enhanced with digital platforms, which are well-suited to Indigenous people’s strengths in art, music, and oral forms of passing on knowledge. The field of mental health has turned to e-supports such as mobile applications (apps) that can provide easy-to-access intervention, when needed. To date, resilience interventions have received comparatively less attention than the study of resilience factors and processes. It is timely to review the extant literature on mental health apps with Indigenous youth as, currently, Indigenous apps are in early research stages. Critically reviewing work to date, it is argued that an inclusive and expansive concept of resilience, coherent with Indigenous holistic health views, is well-positioned as a foundation for collaborative resilience app development. To date, few mental health apps have been researched with Indigenous youth, and fewer have been co-constructed with Indigenous youth and their community members. The current literature points to feasibility in terms of readiness or potential usage, and functionality for promoting an integrated cultural and holistic health lens. As this effort may be specific to a particular Indigenous nation’s values, stories, and practices, we highlight the Haudenosaunee conceptual wellness model as one example to guide Indigenous and non-Indigenous science integration, with a current project underway with the JoyPopTM mHealth app for promoting positive mental health and resilience.
ABC Ophthalmology, 46 years of history
Authors: Lima Vagner Loduca
Published: June 2021

not applicable
Dexamethasone intravitreal implant for macular edema: a pilot study in a public health center
Authors: Crespo Maria Júlia Izzo , Carbajo Cristina Nery , Veiga Glaucia Luciano da , Fonseca Fernando Luiz Affonso , Lima Vagner Loduca , Abucham Neto Júlio Zaki
Published: June 2021

Introduction: Macula edema consists in one of the most common causes of visual impairment. Objective: To evaluate the safety and efficacy of continuous release of 0.7 mg dexamethasone (using implantable device) for treatment of macular edema. Methods: Cross-sectional observational study of 16 patients treated with 0.7 mg dexamethasone intraocular implant. Visual acuity, intraocular pressure and central macular thickness were recorded at baseline, 1-month and 3-month follow-up. Results: 15 eyes of 13 patients were included. Most eyes (n=9) improve visual acuity from baseline at 1-month follow-up; this improvement persisted through 3-monyh follow-up in six eyes. The central macular thickness decreased in the majority of the subjects at 1-month (n=12) and at 3-month (n=10) follow-up. Three eyes presented with elevated intraocular pressure. Conclusion: Dexamethasone implant can both reduce the risk of vision loss and improve anatomical features of macular edema due to several pathologies studied. This implant may be used safely and should be considered a therapeutic option to Brazilian Public Health System.
Protein-based condensation mechanisms drive the assembly of RNA-rich P granules
Authors: Schmidt Helen , Putnam Andrea , Rasoloson Dominique , Seydoux Geraldine
Published: June 2021

Germ granules are protein-RNA condensates that segregate with the embryonic germline. In Caenorhabditis elegans embryos, germ (P) granule assembly requires MEG-3, an intrinsically disordered protein that forms RNA-rich condensates on the surface of PGL condensates at the core of P granules. MEG-3 is related to the GCNA family and contains an N-terminal disordered region (IDR) and a predicted ordered C-terminus featuring an HMG-like motif (HMGL). We find that MEG-3 is a modular protein that uses its IDR to bind RNA and its C-terminus to drive condensation. The HMGL motif mediates binding to PGL-3 and is required for co-assembly of MEG-3 and PGL-3 condensates in vivo. Mutations in HMGL cause MEG-3 and PGL-3 to form separate condensates that no longer co-segregate to the germline or recruit RNA. Our findings highlight the importance of protein-based condensation mechanisms and condensate-condensate interactions in the assembly of RNA-rich germ granules.
Echocardiographic Assessment of Cardiac Function in Liver Cirrhosis: A Cross-sectional Study
Authors: Nirmal Apoorva , Agrawal Gajendra , Kumar Sunil , Acharya Sourya , Dafal Akshay , Bhushan Dwivedi
Published: June 2021

Introduction: Echocardiography is a noninvasive method to assess the cardiac dysfunction in liver cirrhosis. Early detection of cardiac dysfunction helps prevent morbidity in patients undergoing haemodynamics altering procedures like liver transplant or Transjugular Intrahepatic Portosystemic Shunt (TIPSS) or those who have haematemesis. Aim: This study had been planned to assess the cardiac dysfunction and its incidence among patients of liver cirrhosis. Materials and Methods: In this cross-sectional study total of 150 individuals with liver cirrhosis were enrolled and cardiac assessment was done in the form of systolic and diastolic dysfunction by 2D Echocardiography. It was correlated with the aetiology and severity of liver cirrhosis was assessed by Child Pugh’s criteria. The grading of diastolic dysfunction was done on the basis of Early/Late (E/A) Left Ventricular (LV) filling ratio as Grade I (impaired relaxation pattern) E/A<0.8, Grade II (Pseudo normal) as E/A 0.8-1.5, and Grade III (Restrictive filling) E/A >2. Statistical analysis was done by using Chi-square test and Pearson’s Correlation Coefficient and p<0.05 is considered as level of significance. Results: Out of the 150 patients of liver cirrhosis, cardiac dysfunction was noted in 51. Among 93 (62%) patients who had alcoholic aetiology, 4 (44.4%) had systolic dysfunction whereas 29 (69.04%) had diastolic dysfunction. Among 9 patients of Left Ventricular (LV) systolic dysfunction 2 (22.2%) patients were in grade A Child Pugh, 4 (44.4%) in grade B and 3 (33.4%) in grade C, all being statically significant (r=0.195; p=0.017). LV diastolic dysfunction was seen in 17 (20.2%) of Grade A, 14 (25%) of Grade B and 11 (100%) of Grade C of Child Pugh Score, all being statistically significant and well correlated according to severity (r=0.199; p=0.004). Conclusion: The cardiac dysfunction was directly correlated with severity of liver cirrhosis according to Child Pugh scoring criteria thereby suggesting that possible cardiac changes were due to cirrhosis and not alcohol.
Adherence to Land use Zones in Implementation of Participatory Village Land use Planning Policy in Ulanga District in Tanzania
Authors: Naiposha M. N. , Nzunda E. F.
Published: June 2021

Proper implementation of land use planning may contribute to solving land use problems, including land use conflicts. Adherence to land plans depends on many factors which vary according to circumstances of a study area. The present study aims to contribute to knowledge needed to enhance adherence to zones in land use planning. Specifically, the study had two objectives, namely: (1) to examine extent of adherence to village land use plans and, (2) to assess factors that influence adherence to the village land use plans. Data were collected through household survey of 120 respondents from two villages, key informants, focus group discussions, field observation, review of guidelines for land use planning, village land use plans (VLUPs), district land use framework, books and journal articles. GPS points to examine adherence to VLUPs were analyzed using Kappa statistic. Factors influencing adherence to VLUPs were analysed using binary logistical regression and pair-wise ranking. There was moderate adherence with kappa coefficient of 0.47 and 0.49 for Iragua and Kichangani villages. Larger families with higher incomes were more likely not to adhere to land use plans. Immigrants were also more likely not to adhere to plans than residents. Corruption of village leaders, lack of follow up by village leaders on implementation, lack of awareness on land use plans and underestimated population growth were the key prioritised factors that resulted in non-adherence of land use plans. The study recommends a review of the zoning standards to enhance sufficiency of allocated zones; privatization of grazing land; establishment of communal grazing management plans; and involvement of communities in developing complete plans. The study also recommends close monitoring; reviewing of VLUPs; enforcement of good governance; establishing incentive schemes; offering continuous education and developing participatory implementation framework.
Molecular Diversity Analysis in Boro Rice (Oryza sativa L.) Landraces using SSR Markers
Authors: Vabna Farhana Afrin , Islam Mohammad Zahidul , Prince Md. Ferdous Rezwan Khan , Hoque Md. Ekramul
Published: June 2021

Aims: The aim of the study was to determine the genetic diversity of twenty four Boro rice landraces using rice genome specific twelve well known SSR markers.

Study Design: Genomic DNA extraction, PCR amplification, Polyacrylamide gel electrophoresis (PAGE) and data analysis-these steps were followed to perform the research work. Data was analysed with the help of following software; POWERMAKER version 3.25, AlphaEaseFC (Alpha Innotech Corporation) version 4.0. UPGMA dendrogram was constructed using MEGA 5.1 software.

Place and Duration of Study: The study was conducted at the Genetic Resources and Seed Division (GRSD), Bangladesh Rice Research Institute (BRRI), Joydebpur, Gazipur, Bangladesh during the period of November 2017 to March 2018.

Methodology: Simple Sequence Repeat (SSR) markers were used to assay 24 landraces of Boro rice collected from the Gene Bank of Bangladesh Rice Research Institute (BRRI).

Results: A total fifty four (54) alleles were detected, out of which forty five (45) polymorphic alleles were identified. The Polymorphic Information Content (PIC) of SSR markers ranged from 0.08 (RM447) to 0.84 (RM206) with an average value of PIC = 0.49. Gene diversity ranges from 0.08 (RM447) to 0.86 (RM206) with an average value of 0.52. The RM206 marker can be considered as the best marker among the studied markers for 24 rice landraces. Dendrogram based on Nei’s genetic distance using Unweighted Pair Group Method of Arithmetic Mean (UPGMA) indicated the segregation of 24 genotypes into three main clusters.

Conclusion: The result revealed that SSR markers are very effective tools in the study of genetic diversity and genetic relationships and this result can be conveniently used for further molecular diversity analysis of rice genotypes to identify diverse parent for the development of high yielding variety in rice.
Phosphorus Sorption in Soils Overlying Basement Complex Rock, Alluvium, Coastal Plain Sand and Imo Shale Parent Materials
Authors: Orhue Robert Ehi , Emomu Adams , Obazuaye Esohe , Erhayimwen Aimiesomon Michael , Bepo Ajayi Gboyega
Published: June 2021

This study aimed at evaluating phosphorus (P) sorption capacities in Soils overlying basement complex Rock (A), Alluvium (B), coastal plain sand (C) and Imo shale (C) parent materials.

Completely randomized design was used to collect soil samples from 5 depths in 3 replications from Idanre, Koko, NIFOR and Uhomora in Nigeria.

Samples collected were analyzed in the central analytical laboratory of the Nigerian Institute for Oil palm Research, Benin City, Nigeria between march 2016 and September 2017.

60 soil samples were equilibrated in 25 ml of 0.01 M CaCl2 containing various concentration of P as KH2PO4  to give 0, 50, 100, 150, 200 and 250 mg/L P for 24 hours (h)  at room temperature 25 ± 2 oC. Genstat statistical package was used to calculate Analysis of variance, correlation of Phosphorus sorption index (PSI) with soil properties, coefficient of variation, means separation and Least Significant difference (LSD).

The rate and %P adsorption increased with increasing concentration of P added to the soils. The P sorption capacities of the soils considering Freundlich model decreased in the order of D > B > C >A. %P adsorbed was highest in D soils with value of 15.19% for 100 mg/kg P added. The PSI correlated with organic carbon r = -0.58 P ≤ .05 in C soils, r = 0.44 P ≤ .05 in D soils, it also correlated with N r = -0.58 P ≤ .05 in C Soils, K r = 0.57 P ≤ .05, r = 0.49 P ≤ .05 in C and D soils respectively.

D soils sorbed more P than other soils hence the D soils will require more P fertilization to attain optimum P concentration in soil solution, however further study is required to determine the form of P sorbed by these parent materials.
Prevalence of Streptococcus pneumoniae in Pneumonia Patients that Attend Madonna Catholic Hospital Umuahia, Abia State, Nigeria
Authors: Nwankwo Immaculata U. , Edward Kelechi C. , Nwoba Chinedu N. , Ike Moses O.
Published: June 2021

Aim: To determine the prevalence of Streptococcus pnenumoniae in pnenumonia patients attending Madonna Catholic Hospital, Umuahia; Abia State.

Methods: The study was a cross-sectional study on the prevalence of Streptococcus pnenumoniae among patients in Madonna Catholic Hospital, Umuahia. It lasted for a period of three months (September 2019 to January 2020). Standard microbiological techniques were used to evaluate 60 sputum samples collected from pneumonia patients and the modified Kirby-Buar disk diffusion technique was used to test the sensitive pattern of the isolates to some antibiotics.

Results: A total of thirty-three (33) Streptococcus pneumoniae isolates were recovered from sixty (60) sputum samples from pneumonia patients. 17(51%) were gotten from male and 16 (49%) of isolates were gotten from female. The highest frequency of occurrence among the age groups was observed with adults (19-59 years) (34.4%) followed by adolescence (13-18 years) (33.3%), while the least frequency was from those of senior adults (>60) (9.1%). However, the antibiotic susceptibility pattern of the Streptococcus pneumoniae isolates from the sputum samples shows varying degrees of sensitivity and resistance to the antibiotics. From the study, Streptomycin and Cotrimoxazole showed a high percentage of sensitivity against Streptococcus pneumoniae isolates at 78.8% and 72.7% respectively. The highest percentage of resistance was observed with Gentamicin and Tetracycline at 42.4% each.

Conclusion: This study highlights that there was no distinct variation in occurrence of Streptococcus pneumoniae in relation to gender and age. As most patients were hospitalized in separated wards, this suggests a role for local dissemination of this bacterium in the respective wards rather than age or gender specific predilection. This study also suggests that streptomycin and Cotrimoxazole could be a drug of choice in the treatment of pneumonia.
Gavarret, Jules‐Denis‐Jules
Authors: Matthews J. Rosser
Published: June 2021

Gavarret (1809–1890) was medically qualified. In 1840, he published an influential book on medical statistics drawing on the probabilistic results of S.D. Poisson concerning the sampling error of a proportion.
Dynamic Acoustic Levitator Based On Subwavelength Aperture Control
Authors: Lu Xiaolong , Twiefel Jens , Ma Zhichao , Yu Tingting , Wallaschek Jörg , Fischer Peer
Published: June 2021

Acoustic levitation provides a means to achieve contactless manipulation of fragile materials and biological samples. Most acoustic levitators rely on complex electronic hardware and software to shape the acoustic field and realize their dynamic operation. Here, the authors introduce a dynamic acoustic levitator that is based on mechanically controlling the opening and (partial) closing of subwavelength apertures. This simple approach relies on the use of a single ultrasonic transducer and is shown to permit the facile and reliable manipulation of a variety targets ranging from solid particles, to fluid and ferrofluidic drops. Experimental observations agree well with numerical simulations of the Gor'kov potential. Remarkably, this system even enables the generation of time‐varying potentials and induces oscillatory and rotational motion in the levitated objects via a feedback mechanism between the trapped object and the trapping potential. This is shown to result in long distance translation, in‐situ rotation and self‐modulated oscillation of the trapped particles. In addition, dense ferrofluidic droplets are levitated and transformed inside the levitator. Controlling subwavelength apertures opens the possibility to realize simple powerful levitators that nevertheless allow for the versatile dynamic manipulation of levitated matter.