bluuebunny/crossref_metadata_2025 huggingface dataset:
Data protection impact assessments in the European Union: complementing the new legal framework towards a more robust protection of individuals
Authors: Kloza Dariusz , van Dijk Niels , Gellert Raphaël , Böröcz István , Tanas Alessia , Mantovani Eugenio , Quinn Paul
Published: October 2020

This paper provides recommendations for the European Union (EU) to complement the requirement for data protection impact assessment (DPIA), as set forth in the General Data Protection Regulation (GDPR), with a view of achieving a more robust protection of personal data. In April 2016 the EU concluded the core part of the reform of its legal framework for personal data protection. The Union is currently preparing implementing measures and guidelines to give full effect to the new legal provisions before their applicability from May 2018. This reform introduces, among other ‘novelties’, a legal requirement to conduct a DPIA. However, this requirement bears a few weak points. In order to inform this on-going policy-making process, the present policy brief attempts to draft a best practice for a generic type of impact assessment, i.e. recommended for different areas (section II). Section III makes an early evaluation of how this best practice relates to the specific impact assessment requirement set forth in the GDPR, i.e. DPIA. These sections are preceded by succinct background information on impact assessments as such: definition, historical overview, and their merits and drawbacks (section I). Section IV concludes this paper by offering recommendations for complementing the DPIA requirement in the GDPR: (1) to expand the scope of the DPIA requirement in the GDPR; (2) to develop methods for conducting such an assessment; (3) to establish ‘reference centres’ on DPIA at data protection authorities (DPAs). This policy brief is addressed predominantly to policy-makers at the EU- and Member State-level, notwithstanding the potential interest it might gain from their counterparts elsewhere in the world.
Does Secure Base Script Knowledge Mediate Associations Between Observed Parental Caregiving During Childhood and Adult Romantic Relationship Quality and Health?
Authors: Dagan Or , Buisman Renate S. M. , Nivison Marissa D , Waters Theodore , Vaughn Brian E. , Bost Kelly K. , Bleil Maria E. , Vandell Deborah , Booth-LaForce Cathryn , Roisman Glenn I.
Published: October 2020

Increasingly, attachment representations are being assessed via secure base script knowledge—the degree to which individuals show awareness of the temporal-causal schema that summarizes the basic features of seeking and receiving effective support from caregivers during times of need. Limited research has assessed the links between secure base script knowledge and aspects of adult functioning or the role that secure base script knowledge may play in accounting for associations between early caregiving quality and adulthood functioning. We used follow-up assessments of the NICHD Study of Early Child Care and Youth Development cohort (N = 585) to examine whether secure base script knowledge as measured by the adolescent version of the Attachment Script Assessment at age 18 years: (a) is associated with later romantic relationship quality (assessed via perceived partner’s warmth and hostility), depressive symptoms, and body mass index (BMI) at age 26 years, and (b) mediates expected associations between the quality of maternal and paternal sensitivity across the first 15 years of life and age-26 outcomes. More access to and elaborated knowledge of the secure base script predicted less extreme hostility with romantic partners, and better emotional and physical health (i.e., fewer depressive symptoms and lower BMI). Moreover, secure base script knowledge mediated links between early maternal and paternal sensitivity and both later romantic partner hostility and depressive symptoms, but not BMI.
Modeliranje dispečerskog sustava za podršku u upravljanju željezničkim prometom u kolodvorskom području temeljenog na neizrazitoj logici (fuzzy logic)
Authors: Haramina Hrvoje , Širol Marin , Sumpor Davor , Petrlić Josip
Published: October 2020

SAŽETAK: Suvremeni pristup upravljanju željezničkim prometom na glavnim koridorima podrazumijeva centralizirano upravljanje željezničkim prometom. U tom je pristupu glavna uloga u upravljanju prometom povjerena dispečeru. Imajući za cilj smanjenje radnog opterećenja dispečera i istovremeno povećanje razine performanse i efikasnosti njegova rada, te veću učinkovitost upravljanja prometom, razvijaju se prikladni sustavi potpore u odlučivanju. Članak prikazuje model sustava podrške u upravljanju željezničkim prometom temeljen na umjetnoj inteligenciji. Predloženi model sustava temeljenog na neizrazitoj logici trebao bi u određenoj mjeri smanjiti negativan učinak različitih distraktora i nepovoljnih okolnosti u radnom i prometnom okruženju na rad dispečera.
Improving financial education strategy for sustainable development
Authors: Margvelashvili Irakli , Kostava Mariami
Published: October 2020

Introduction. Modern society has long agreed that financial education is one of the pillars of its sustainable development. In many countries, action plans were prepared, strategies developed, training courses were aimed at increasing the level of financial education, but after a few years it is again clear that the problem has not been solved, there are very few examples of success and it is not known whether these successes are the result of the above measures. The need of change the strategies in place today in financial education is slowly emerging. There is an urgent task of improving the strategy of financial education at the present stage of development of society.
Aim and tasks. The purpose of this paper is to analyze the current financial education strategy on the example of one particular country – Georgia, its logical consequences and find the levers that will make this strategy more effective or outline the contours of the new strategy.
Results. The results of the work done in Georgia in the field of financial education over the past six years were analyzed. Comparison of the stated goals and actual results of the current strategies of financial education is carried out. The study is based on the analysis of the determinants of financial behavior of human, the main postulates of behavioral economics. The methods of logical generalization, synthesis, analysis and deduction are widely used in the research to reveal the cause-and-effect relationship between mental models of thinking, financial education and financial stability of the individual. Also examined the development policy measures adopted by the World Bank. An assessment of their relevance for improving financial education is carried out. The importance of considering mental models of thinking in achieving goals set in various spheres of society was noticed. Also, as a result of the analysis, new approaches were identified that improve the strategy of financial education.
Conclusions. Strategies need to be developed based on the mental models of the population of a particular country taking into account the psychological aspects that are significant for the members of a given community. It is necessary to process the information provided by the population, not only semantically, but also etymologically, within the framework of the measures outlined in the strategy and use categories in the context to which the society is more sensitive. More successful examples of financial education development policies need to be considered.
Integrated approach to the use of logistics and marketing in the system of commodity markets
Authors: Tarakanov Mykola , Lozova Tetiana , Uzun Ivan
Published: October 2020

Aim and tasks. The purpose of the research is to substantiate the methodological approach to the impact of the integration model of logistics marketing on the effectiveness of reproduction processes in the system of commodity markets. The main objectives of the study are: to determine the essence of the interaction of logistics and marketing at the level of commodity markets, substantiation of the phased scheme of eliminating problem areas as part of the leading characteristics of commodity markets, outlining the impact of integrated logistics marketing model on the theoretical foundations of commodity markets.
Results. With the proposed methodological approach to the use of an integrated model of logistics marketing becomes relevant to situations that are associated with radical transformational shifts in the strategic commodity markets associated with the diversification of foreign markets, the formation of complete supply chains, innovative economic development. etc. The proposed scheme of overcoming the problematic characteristics of certain types of commodity markets indicates the presence of significant reserves for the use of marketing research on the formation of effective logistics chains in the system of reproductive processes of trade.
Conclusions. It is concluded that the main indicators of the effectiveness of taking into account the logistical factor in making marketing decisions are determined - the factor of availability of goods for use, accessibility to the place of use and time of use of goods. The influence of marketing on the formation of logistics chains of the commodity market is determined by the adaptation of logistics to the leading characteristics of commodity markets.
Assessment of innovation and investment potentials as a strategic basis for identification of Smart Specialization of regions of Ukraine
Authors: Andryeyeva Natalya , Tiutiunnyk Hanna
Published: October 2020

Introduction. The key role in maintaining the competitiveness of economic systems belongs to the innovative specialization of economic activity, which diversifies economic activity. The existing methodological approaches to determining the strategic priorities of Smart Specialization of a particular region do not fully take into account the assessment of innovation and investment potential, taking into account the environmental component of sustainable development.
Aim and tasks. The purpose of the proposed study is the formation of scientific approaches to assessing innovation and investment potential in the context of the formation of strategic regional environmental policy in the context of the methodology of Smart Specialization.
Results. The article substantiates the methodological provisions for combining the methodology of Quintuple helix, Smart-specialization and Sustainable Development Goals. The institutional essence of investment and innovation policy of nature management at the regional level as a modern model of Quintuple helix is determined. An assessment of the innovation potential of the regions as a component of investment and innovation policy of nature management. The dynamics of implementation of environmental innovations by enterprises of Ukraine, the concentration of higher education institutions by regions, in particular, subordinate government agencies are analyzed. The number of students, specialists in higher education institutions majoring in natural sciences, employment in the field of nature management has been determined. The strengthening of the ecological component in the scientific and educational spheres is established for the further implement the borrowed knowledge in the formation of investment and innovation policy of nature management of individual regions. The natural resource potential of the country in terms of regions according to the statistical database is studied.
Conclusions. The presented research proposes the author's vision, which allows not only to outline the dominants of Smart Specialization of кegions in order to determine the strategic priorities of investment and innovation policy of the national sphere of nature, but also to explore the uniqueness of regions based on scientific and technical potential. Implementation of the Smart Specialization Strategy, which will combine the methodology of Quintuple helix and Smart Specialization will provide an opportunity to determine the approach to the formation and implementation of state regional policy. A methodological approach to determining the dominants of investment and innovation regional environmental policy has been developed, taking into account the methodology of "Smart Specialization" and in the context of existing European experience.
The concept of public audit in accordance with INTOSAI professional statements (IFPP)
Authors: Drozd Iryna , Pysmenna Mariia
Published: October 2020

Introduction. The article is devoted to the study of improving the types of public audit in accordance with the strategic objectives set by the international organization of supreme audit institutions INTOSAI, which has adopted standards of public audit in the form of professional statements IFPP.
Aim and tasks. The purpose of the article is a theoretical and methodological justification of the process of formation and development of public audit in accordance with new conceptual approaches, formed in accordance with the professional statements of INTOSAI (IFPP), practical recommendations for their practical implementation in Ukraine.
Results. It is established that the problem of state audit in terms of its varieties – performance audit, financial audit, which are regulated by the legislation of Ukraine, is one of the most important prerequisites for ensuring public requests for reliable and transparent information on the use of budget funds. However, as the study showed, insufficient attention was paid by the control bodies, in particular, to the audit of the legislative compliance of the actions of budget managers by the Accounting Chamber. It is proposed within the strategies of ISSAI state audit standards to introduce in Ukraine compliance audit as a type of state audit, which is provided by IFPP professional statements. The expected results of such implementation will allow to increase financial and executive discipline and to prevent illegal spending of budgetary funds.
Conclusions. In the practice of world state audit, a certain structure of types of state audit has been developed, which meets the demands of society and parliaments of the countries regarding the legality, efficiency and reliability of budget spending. The introduction of INTOSAI international standards aims to increase confidence in the state audit, ensures its comprehensive and comprehensive nature, implements effective and efficient professional principles and standards in the practice of domestic specialists. Improving the methodology of public audit generally meets the requirements of ensuring a high level of efficiency of the highest bodies of financial control in the interests of the development of a democratic society. Therefore, the introduction of all types of public audit in accordance with ISSAI standards meets the expectations of society and best international practice. Further developments should reveal the features of the implementation of a new type of state audit – compliance audit in terms of domestic and foreign methods and procedures for performing control actions.
Analytical support for the effective operation of a network retailer
Authors: Fedorenko Oleksandra
Published: October 2020

Introduction. Modern retail integrates the development of goods and services, their production, sale, exchange and consumption into a global network and is a basis for an accelerated development of services and trade. Network retailers offer consumers not only a wide range of goods and services, but also the opportunity to buy everything in one place, where a large retail space offers up to hundreds of thousands of items. It is network retail that has a purposeful impact not only on the economy of an individual country, but also on global economic processes.
The aim of the article is to study the theoretical aspects and develop practical recommendations for improving the analytical efficiency of network retail.
Results. The article examines approaches to the disclosure of the economic category of "retail". The state and peculiarities of the development of domestic network retail, problems and difficulties of their functioning are analyzed. It is determined that the development of network retail requires professional and quality retail branding, which is a complex category and includes the process of brand development for the retail network and includes components: marketing research; internal audit; creation of a unique logo of a retail trade network; development of the spatial environment of the retail trade network. The method of the analysis of activity of the network retailer in particular the complex comparative analysis of the network retail in the dynamic competitive environment is offered and the balanced system of indicators of the analysis of activity of the network retail is offered.
Conclusions. The development of online retail creates new opportunities for business through the introduction of modern information systems, digitalization of production processes and business, the creation of e-shops and interactive storefronts. The activity of network retail, like any other enterprise, requires a qualitative and comprehensive analysis in order to strengthen its position in the market, a stable position in a competitive environment. Therefore, business owners, executives, senior managers and potential investors and business partners should pay significant attention to the analytical support of the effective operation of the network retailer in order to manage business, finance and further increase profitability.
Retour d’expérience d’un hôpital pédiatrique pendant la crise Covid-19 en Île-de-France
Authors: Lecarpentier T. , Guilbert J. , Constant I. , Louvet N. , Corvol H. , Lorrot M. , Rivière S. , Plages B. , Pelle R. , Carbajal R.
Published: October 2020

La crise sanitaire de la Covid-19 du printemps 2020 a peu touché les enfants avec peu d’hospitalisations dans les hôpitaux pédiatriques. Le défi a été d’apporter une aide aux hôpitaux adultes avec un personnel principalement formé à la pédiatrie tout en maintenant la permanence des soins urgents pour les enfants atteints ou non de la Covid-19. À l’hôpital universitaire Armand-Trousseau, nous avons créé des unités dédiées pour les enfants atteints de la Covid-19, identifié les spécificités des enfants atteints de la Covid-19 et notamment les formes de Kawasaki like ou PIMS (paediatric multisystem inflammatory syndrome), créé une unité de réanimation adulte au pic de l’épidémie pour augmenter les capacités en lits de réanimation dans notre région, mutualisé notre centre de dépistage pour le personnel d’hôpitaux adultes. Enfin, nous avons envoyé plus de 140 personnels médicaux et paramédicaux dans les hôpitaux adultes de notre groupe hospitalier. Cette aide a pu être organisée grâce aux liens étroits établis par des cellules de crises communes avec les hôpitaux adultes de notre groupe hospitalier. Nous rapportons ainsi un retour d’expérience d’un hôpital pédiatrique au cours de la crise de la Covid-19 en Île-de-France.
Retour d’expérience sur la direction médicale de crise à l’Assistance publique–Hôpitaux de Paris pendant la crise Covid-19
Authors: Riou B. , Cariou A. , Duranteau J. , Langeron O. , Crestani B. , Adnet F. , Raux M.
Published: October 2020

Un retour d’expérience sur la direction médicale de crise (DMC) pendant la première phase de l’épidémie de Covid-19 a été effectué à l’Assistance publique–Hôpitaux de Paris (AP–HP), le plus important centre hospitalier universitaire européen. L’AP–HP s’est dotée d’un directeur médical de crise (DMC) AP–HP, de six DMC de groupes hospitaliers (GH) et d’un DMC pour chacun des 39 sites hospitaliers. Le pilotage s’est appuyé sur des réunions quotidiennes de crise AP–HP et de GH, des groupes de travail disciplinaires et des tableaux de bord quotidiens fiabilisés qui ont permis d’optimiser les actions. Des actions innovantes ont été mises en place : cellules de régulation des entrées et des sorties de réanimation, suivi des patients infectés à domicile, traçage des contacts, transferts interrégionaux de patients de réanimation. Les éléments clés de la réussite ont été les relations entre direction générale et DMC, l’articulation entre l’échelon central (AP–HP) et celui des GH, la mobilisation de tous les acteurs vers un objectif unique identifié et la mobilisation de l’ensemble des soignants, y compris les étudiants. Parmi les pistes d’amélioration soulignées, il convient de citer la généralisation des DMC hors AP–HP, conformément à la réglementation, le développement de la connaissance du mode de fonctionnement de crise, l’anticipation de la formation à la gestion de crise, la réalisation d’une information quotidienne de l’ensemble des acteurs des actions menées dans une crise de longue durée et la participation des représentants des usagers. La gestion de la recherche en temps de crise reste à inventer au niveau national, voire européen.
Retour d’expérience sur la cellule régionale d’appui à la régulation des lits de réanimation Covidréa pendant la crise Covid-19
Authors: Leroy C. , Treluyer L. , Hellmann R. , Cléry R. , Haab F. , Parc Y.
Published: October 2020

La disponibilité des lits de réanimation a été un enjeu majeur de la gestion de la crise Covid-19, imposant aux acteurs régionaux de construire une réponse coordonnée et novatrice pour apporter une réponse en termes de recherche de place. Dans la région Île-de-France, la mise en place du dispositif a été constituée par deux mesures : la refonte du répertoire opérationnel des ressources (ROR) et la création d’une cellule d’appui régionale (Covidréa) comportant des cellules médicale et administrative. Les opérateurs de la cellule médicale étaient des chirurgiens volontaires sous la supervision d’un médecin urgentiste, chargés des actions de recherche et de régulation des demandes. La cellule administrative a vérifié la pertinence des informations du ROR sur un rythme pluriquotidien. La mobilisation des acteurs locaux (anesthésistes et réanimateurs) a permis d’obtenir des données actualisées du ROR quasiment en temps réel. La crise sanitaire Covid-19 a mis en lumière les faiblesses des systèmes d’information, particulièrement la connaissance de la disponibilité en lits de réanimation en temps réel. Une démarche collective pour construire de nouveaux outils de pilotage adaptés au quotidien, dans le cadre des tensions hivernales (bronchiolite, grippe) ou saisonnières (canicule), et la gestion des situations sanitaires exceptionnelles est impérative. Il est nécessaire d’intégrer cette fonction dans la mission des Samu départementaux en temps ordinaire et des Samu zonaux en temps de crise, en particulier dans la logique de construction du futur service d’accès aux soins (SAS).
Schemata in the Graphic Novel Persepolis
Authors: Strömberg Fredrik
Published: October 2020

It has repeatedly been suggested that the art in the graphic novel Persepolis by Iranian French artist Marjane Satrapi contains numerous connections to ancient Persian art forms, to the point of this becoming a ‘truism’, although the claim has not been subjected to in-depth analysis. The present formal analysis employs Gombrichian schema theory to identify visual elements in the graphic novel potentially connected to Persian visual cultures to discern if and how they might relate to their proposed influences and how they integrate with styles and visual conventions in comics. The results indicate that there are indeed connections, although integrated into the art form of comics through combination and accommodation, and that this reinforced the Persian theme of the graphic novel and potentially enriched the art form of comics.
Serving library users during a pandemic: the case of Karlstad University Library, Sweden
Authors: Harnesk Jakob , Eriksson Marie-Louise
Published: October 2020

During March 2020, all Swedish universities moved their teaching to an online environment due to the Covid-19 outbreak. Karlstad University Library in Sweden made a number of changes in order to reduce the spread of infection while at the same time maintaining a high level of library services to its users. Opening hours were drastically reduced. All study spaces were closed. Most of the staff were working from home. A new virtual reference desk via Zoom was launched to increase the library office hours. Since things happened fast, the internal staff training was done while at the same time providing the new reference service to the users. Some initial mistakes were made but in general, this ‘learn-as-you-go method’ worked surprisingly well.
[FY1478] The Art of Goodbye: A Closer Look at Emerging Trends in End-of-Life Rituals
Authors: Spence Lynda M
Published: October 2020

Each year in a diverse United States, 2.5 million people die (CDC). Naturally, a one-size-fits-all final goodbye does not exist. Compounded by increased access to information, survivors as consumers are increasingly seeking alternatives to the conventional funeral. For some, tradition continues to inform, but for others, options and choices are evolving and have become a new normal.Creativity or a new direction may be the impetus for variations but budget is clearly a factor for others. Funerals are among the most expensive purchases made in a lifetime, yet due to rare or infrequent experience, individuals and families have scant knowledge of the process. Time constraints (unless pre-planning has been established) and decision-making during a period of duress, grief, and guilt can result in missteps and overspending.
Building Coalitions: Coalition Facilitator Guide
Authors: Bell Charles H. , Smith Penne , Bolton Elizabeth B. , Guion Lisa
Published: October 2020

This document is FY494, Part 2 of the 16 part series adapted for use in Florida by Elizabeth B. Bolton and Lisa Guion. Reprinted with permission March, 1997. Revised April, 2002.
Building Coalitions: Coalition Functioning
Authors: Bell Charles H. , Smith Penne , Bolton Elizabeth B. , Guion Lisa
Published: October 2020

This document is FY495, Part 3 of the 16 part series adapted for use in Florida by Elizabeth B. Bolton and Lisa Guion. Reprinted with permission March, 1997. Revised April, 2002.
Melatonin inhibits growth of B16 melanoma in C57BL/6 mice
Authors: Agil Ahmad , Benhaj Khemais , Navarro-Alarcon Miguel , Abdo Walied , Zourgui Lazhar , Entrena José Manuel , Reiter Russel J
Published: October 2020

Melatonin (N-acetyl-5-methoxytryptamine) has oncostatic properties in a wide variety of tumors. In melanoma, melatonin displayed growth suppressive effects in cultured cell lines and tumors. Thus far, however, there is no evidence of orally administrated melatonin reducing melanoma tumor growth. Therefore, the current study investigated the preventive effect of melatonin on C57BL/6 mice injected with B16-F10 murine metastatic melanoma cells. The animals were divided into two groups; control (vehicle) and melatonin pre-treated with oral melatonin in the drinking water (10 mg/kg/day) for 15 days. Grossly, the control animals had a significant exponential increase in tumor size until day 33, and all control animals were dead by day 38; conversely, melatonin pre-treated mice demonstrated delayed tumour appearance as well as decreased tumour volume and increased survival rates. PCNA immunostaining corroborated these data and demonstrated a significant reduction in the number of proliferating cells in the melatonin-treated mice (P < 0.005). Interestingly, histopathological analysis revealed the presence of undifferentiated and pleomorphic cells associated with higher mitotic rate in the control group, while epithelioid-shaped cells, sometimes containing melanin were clearly identified in melatonin-treated animals. Mitochondrial parameters measurement showed greater PTP opening and increased mitochondrial nitrite level associated in melatonin-pretreated animals. Finally, the decreased P-ERK1,2 cytoplasmic expression in melatonin mice compared with the controls supports the conclusion that the MAPK signalling pathway is repressed by melatonin in B16-F10 melanoma. Collectively, these results suggest for the first time that orally-administered melatonin reduces malignant melanoma progression in vivo and increases the percent of survival by lowering tumor cells proliferation due to mitochondrial dependent cytotoxicity and decreased P-ERK1,2 expression. This study demonstrates the chemopreventive potential of melatonin against malignant melanoma in C57BL/6 mice.
Melatonin regulates the expression of Bone Morphogenetic Protein 15 (Bmp-15), Growth Differentiation Factor 9 (Gdf-9) and LH receptor (Lhr) genes in developing follicles of rats
Authors: Coelho Lia Alencar , Buonfiglio Daniella Do Carmo , Kuwabara Wilson Mitsuo T , Andrade-Silva Jéssica , Gomes Patrícia Rodrigues Lourenço , Scialfa Julieta Helena , Peres Rafael , Amaral Fernanda Gaspar , Cipolla-Neto José
Published: October 2020

This study investigated the effects of melatonin supplementation on the daily mRNA expression of Bmp-15, Gdf-9, FSH (Fshr) and LH (Lhr) receptor genes and the effect of gonadotropin supplementation on protein expression of melatonin-synthetizing enzymes (ASMT and AANAT) during in vitro maturation (IMV) of rat follicle-enclosed oocytes. We also studied the effects of pinealectomy on the mRNA expression of Bmp-15, Gdf-9, Fshr and Lhr genes in immature oocytes and cumulus cells and on the protein expression and immunolocalization of AANAT and ASMT in immature ovaries. Ovaries were collected from sham-pinealectomized (INTACT) and pinealectomized (PINX) females during the light and dark phases of the 12h:12h light-dark cycle. Melatonin increased the Bmp-15 and Gdf-9 mRNA expression in follicle-enclosed oocytes during dark phase and Lhr mRNA expression during the light phase. The daily mRNA expression of Lhr was negatively correlated with the daily mRNA expression of Bmp-15 and Gdf-9 in follicle-enclosed oocytes supplemented with melatonin. There were no phase differences in oocytes mRNA expression of Bmp-15 and Gdf-9 from PINX females. Pinealectomy did not altered the mRNA expression of Lhr gene in cumulus cells. There were no phase differences in ASMT and AANAT expression in ovaries from INTACT and PINX females and their immunolocalization was seen in most of ovarian cells. AANAT expression in follicle-enclosed oocytes supplemented with LH from INTACT and PINX females was greater during the dark phase. The results suggest that melatonin regulates the daily Bmp-15, Gdf-9 and Lhr mRNA expression during the rat follicle development. There is also an indicative that melatonin plays an important role in the relationship between the daily expression of Lhr and the daily expression of Bmp-15 and Gdf-9 in follicle-enclosed oocytes during oocyte maturation process.
Low melatonin as a contributor to SARS-CoV-2 disease
Authors: Pandi-Perumal Seithikurippu R , Cardinali Daniel P , Reiter Russel J , Brown Gregory M
Published: October 2020

That the pineal gland is a source of melatonin is widely known; however, by comparison, few know of the much larger pool of extrapineal melatonin. That pool is widely distributed in all animals, including those that do not have a pineal gland, e.g., insects.  Extrapineal melatonin is not released into the blood but is used locally to function as an antioxidant, anti-inflammatory agent, etc. A major site of action of peripherally-produced melatonin is the mitochondria where it neutralizes reactive oxygen species (ROS) that are generated during oxidative phosphorylation. Its role also includes major actions as an immune modulator reducing overreactions to foreign agents while simultaneously boosting immune processes. During a pandemic such as coronavirus disease 2019 (COVID-19), caused by the virus SARS-CoV-2, melatonin is capable of suppressing the damage inflicted by the cytokine storm. The implications of melatonin in susceptibility and treatment of COVID-19 disease are discussed.
Pelatihan Kesiapsiagaan Bencana kepada Peserta Didik SMA Muhammadiyah 1 Palangka Raya
Authors: Irwani Irwani , Hidayat Rachmat
Published: October 2020

The people of Palangka Raya city, especially millennials, especially students who are currently a small part of the Indonesian population who are prone to disasters and are responsible for maintaining the local wisdom of the Indonesian people in the face of disasters. It is these millennials who must receive disaster preparedness training in order to reduce the impact of a bigger disaster. Solutions that can be given to increase public knowledge, especially millennials, about disaster management and preparedness to reduce the more significant impact of disasters occur, namely by providing training to students of SMA Muhammadiyah 1 Palangka Raya.
Pelatihan Pembelajaran dan Penilaian Berbasis HOTS Bagi Guru SD Se-Kecamatan Mantrijeron Kota Yogyakarta
Authors: Wangid Muhammad Nur , Mustadi Ali , Syamsudin Amir , Hastuti Woro Sri , Perwitasari Ningrum , Noor Ady Ferdian , Kusrini Eni , Prihandoko Yogi
Published: October 2020

Higher Order Thinking Skills (HOTS) is a way that puts forward critical and creative values ??so that it is seen as being able to provide solutions in facing the times. The method used is descriptive to describe HOTS-based learning and assessment. The purpose of this activity is to improve the ability of elementary school (SD) teachers in designing HOTS-based learning tools consisting of lesson plans and HOTS-based assessments. This activity is motivated by the skills faced by elementary school teachers in the implementation of the 2013 curriculum, especially in designing and implementing HOTS-based learning, as well as developing HOTS-based assessments. Therefore, this activity aims to make teachers become professionals in educating elementary students in developing children's thinking skills at a higher level.
Pelatihan Usaha Tani Microgreens bagi Ibu Rumah Tangga
Authors: Sukmawani Reny , Rini Neneng Kartika , Supiati Inda Asri , Meilani Ema Hilma , Milla Amalia Nur , Astutiningsih Endang Tri
Published: October 2020

This Community Service is entitled Microgreens Farming Business Training for Housewives in Sukabumi. The empowerment of housewives is intended to produce the potential of housewives, in addition to being able to carry out domestic or domestic duties. Housewives are also able to be active and productive in public activities and economic activities. Microgreens are vegetable seeds that are harvested very young, 7-14 days after germinating and young leaves appear. The method used in this service is the training method; namely, before carrying out direct practice, participants understand through theory first. The training participants were housewives from several women's organizations in Sukabumi. This community service is the acquisition of skills of housewives in farming microgreens and the increasing role of housewives in family welfare through the provision of healthy vegetables for the family.
Pemberdayaan bagi Masyarakat Mudah dan Bisa Jadi Usaha Rumahan Melalui Pelatihan Pengembangan Wirausaha Cara Ternak Ikan Cupang Di Kelurahan Putat Jaya Surabaya
Authors: Sutanto J E , Melinda Tina , Kodrat David Sukardi
Published: October 2020

The purpose of community empowerment activities is a caring action from the Implementation Team of Ciputra University Surabaya towards the community to increase knowledge and carry out easily with direct practice. These community empowerment activities use lecture methods, group discussions, entrepreneurship training, FGDs, and the practice of operating facilities and infrastructure. First, about the importance of raising betta fish and an easy way to prevent dengue hemorrhagic fever (DHF), so that public health factors become better and the possibility of contracting DHF is relatively slight. Statistical data in the city of Surabaya shows a significant decrease in DHF sufferers. Second, after being given entrepreneurship development training, it is hoped that the community individually can become a home-based business opportunity as well as making it an effort to empower the citizens' economy, bearing in mind that raising betta fish can have additional income for the community. Third, the location factor of Putat Jaya Village is very strategic, so that it becomes a business opportunity for the Putat Jaya community, especially for prospective consumers from inside and outside Surabaya to reach locations to get betta fish more efficiently.
Aikuisten ammatillisen peruskoulutuksen suunnittelusta
Authors: Virkkunen Jaakko
Published: October 2020

Artikkeli pohjautuu Aikuisten ammatillisen peruskoulutuksen toimikunnan mietintöön ja siinä esitettyihin kehittämisen perusteisiin. Erityistä huomiota kiinnitetään perinteisen ammattianalyysin käyttöön ammatillisen koulutuksen suunnittelussa sekä arvioidaan tämän analyysitavan käyttökelpoisuutta työtehtävien nopeasti muuttuessa. Artikkelissa esitetään ammatillisen opetuksen kehittämistä lähtökohtana kokonaiskuva työprosessista ja sen tutkiminen ja erittely.
Työsuojelun ja työsuojelukoulutuksen yhteiskunnallistuminen
Authors: Riikonen Eila , Kämäräinen Markku
Published: October 2020

Artikkelissa käsitellään työsuojelua yhteiskunnallisena ilmiönä ja siitä työsuojelukoulutukselle aiheutuvia kehittämistarpeita.
Ammatillisen aikuiskoulutuksen asema 80-luvulla
Authors: Honka Juhani
Published: October 2020

Lectio väitöstilaisuudessa 12.5.1984
Substrates and cultivation environments in the production of seedlings of Genipa americana L. (Rubiaceae) seedlings
Authors: Faria Tatiane Aparecida Curim , Curi Thayla Morandi Ridolfi de Carvalho , Santo Tiago Lima do Espírito , Vieira Gustavo Haralampidou da Costa , Costa Edilson , Larson Léia Carla Rodrigues dos Santos , Binotti Flávio Ferreira da Silva
Published: October 2020

This study aimed to evaluate genipap seedling formation in different protected environments using different substrates. Five protected cultivation environments (E) were used: E1 - greenhouse without aluminized shade cover under polyethylene film; E2 - greenhouse with aluminized shade cover under polyethylene film; E3 - screened with black shade cover; E4 - screened with aluminized shade cover; and E5 - nursery covered with bacuri coconut straw. In each protected cultivation environment, substrates containing different percentages of earthworm humus (H), vermiculite (V), bovine manure (M) and shredded cassava stems (C) were tested. Seedlings emerged best in environments E2, E3 and E4. Mixtures ¾ H + ¼ V and ¾ H + ¼ C favored growth and yielded high quality seedlings. Environments E3 and E4 provided superior growth, with better- quality and high-quality seedlings. Environments E1 and E5 did not provide adequate seedling growth. Therefore, were not recommended for genipap seedling production using the substrates tested.
A gestão do conhecimento em serviços transportes, um estudo bibliométrico
Authors: Braz Erivelton Toreta , Nunes Isabel Matos
Published: October 2020

Em meio á busca pela inovação em eficiência produtiva as organizações lançam mão de diversos artifícios, assim o presente estudo tem como proposta identificar como o fragmento da literatura científica mundial aborda o tema “Gestão do Conhecimento (GC)” no contexto dos “Serviços de Transportes”. Para isso emprega a bibliometria como ferramenta metodológica tendo como fonte de pesquisa o portal “Periódicos CAPES/MEC”. Os resultados apontam um equilíbrio na dispersão de pesquisas com ênfase em atividades em organizações públicas e privadas, contudo as abordagens utilizadas apontam em direções distintas. Enquanto as pesquisas com ênfases públicas abordam as contribuições da Gestão do Conhecimento (GC) nas estratégias para melhorias no transporte público e avanço nas ações acerca da transparência, as investigações de cunho privado interpelam elementos voltados aspectos logísticos de transporte na cadeia produtiva como gerenciamento de frota, cooperação entre organizações, sustentabilidade ambiental e controle de custos. Quanto aos processos de GC, nota-se a predileção no debate a aspectos voltados aos processos de aquisição, distribuição e utilização do conhecimento à aspectos relacionados ao armazenamento. De forma geral os estudos sugerem a viabilidade da utilização dos processos de GC com contribuições significativas nas diferentes ênfases e abordagens. Dentre as limitações o estudo apontou um baixo índice de pesquisas na temática, indicando uma avenida de conhecimento a ser seguida.
Fatores socioambientais e prevalência de enteroparasitas em pacientes em hemodiálise no pantanal mato-grossense, Brasil
Authors: Alencar Bianca Teshima de , Zanetti Andernice dos Santos , Vilella Shaiana Hartwig , Araújo Marta dos Santos Miranda de , Silva Larissa Nayara Lima , Alencar Rafael Teshima de , Espinosa Omar Ariel , Malheiros Antonio Francisco
Published: October 2020

Pacientes em tratamento de hemodiálise devido ao seu sistema imunológico diminuído são facilmente acometidos por enteroparasitas, que levam a uma piora do quadro de saúde destes indivíduos. O objetivo desta pesquisa foi identificar a prevalência de enteroparasitas nos pacientes renais crônicos em tratamento de hemodiálise e possíveis associações com os fatores socioambientais. Trata-se de um estudo transversal com 53 pacientes. Para análise de associação foi utilizado os testes qui-quadrado (x²) de Pearson e Razão de Odds (OR). Os exames coprológicos foram analisados utilizando as técnicas de Hoffman e Sheather. A positividade de enteroparasitas atingiu 92.5%, sendo Blastocystis sp. o mais predominante (95.9%). Em relação aos helmintos, apenas Ascaris lumbricoides foi encontrado (4.1%). Infecções mistas apareceram em 53% dos casos. A associação dupla mais comum foi entre Blastocystis sp. e Endolimax nana, observada em 22.4% dos casos. Nossos resultados mostraram alta prevalência de protozoários de repercussão preocupante para saúde desses pacientes como Cryptosporidium sp., Giardia lamblia e Entamoeba histolytica, evidenciando a necessidade de estratégias de prevenção das infecções parasitárias e intervenções adequadas nos pacientes sob tratamento de hemodiálise.
Variabilidade dos índices de aridez e aplicabilidade da equação de perda de solo no município de Amparo de São Francisco - Sergipe, Brasil
Authors: França Manoel Vieira de , Medeiros Raimundo Mainar de , Araújo Wagner Rodolfo de , Holanda Romildo Morant de
Published: October 2020

A erosividade pluvial é um dos elementos da Equação Universal de Perda de Solo, que quantificam as decorrências das chuvas e seu escoamento superficial na erosão do solo. Têm-se como objetivo determinar o índice de aridez realizando sua classificação climática e nível de susceptibilidade erosiva e o cálculo da perda do solo através de sua equação no município de Amparo de São Francisco estado de Sergipe. Utilizaram-se dados de precipitações e temperaturas médias mensais e anuais para o período de 1963 a 2019. A evapotranspiração foi calculada pelo método do balanço hídrico climatológico, gerando-se os índices de aridez. As variáveis topográficas apresentaram dados a respeito do escoamento superficial, e da alta probabilidade de existência de erosões lineares na região de estudo, fatos constatados nas duas visitas de campo e registrados com fotos da zona de estudo. Aliado ao escoamento superficial, pode-se inferir também a degradação do revestimento do pavimento devido o excesso de umidade. As flutuações presentes nos índices erosivos e o desenvolvimento populacional precisam ser explorados visando verificar possíveis contribuições nas alterações climáticas da área estudada, região que apresentaram maiores ocupações de áreas de risco, refletindo em maiores desastres naturais. Espera-se que os resultados apresentados neste estudo forneçam informações aos gestores de políticas públicas, subsídios na elaboração de projetos que venham minimizar tal vulnerabilidade, especialmente para quem vive nas áreas de risco, por meio da prevenção e mitigação de eventos catastróficos que podem ocorrer devido ao excesso ou escassez de chuvas.
Transposições curriculares e concepção de prática nos projetos pedagógicos de cursos de licenciatura em química em um Instituto Federal
Authors: Vasconcelos Rosa Maria Oliveira Teixeira de , Fireman Elton Casado
Published: October 2020

Neste manuscrito objetivou-se apresentar as concepções de prática identificadas a partir de uma investigação sobre a formação inicial de professores em três licenciaturas em química em unidades acadêmicas da rede federal de educação, profissional e tecnológica em Pernambuco, Brasil. Foram analisados os projetos pedagógicos dos três cursos em que observou-se particularmente a concepção de prática a partir dos componentes curriculares “prática como componente curricular” e “estágio supervisionado”. A pesquisa qualitativa do tipo análise documental teve os dados analisados com base na técnica de análise de conteúdo (Bardin, 2011; Moraes, 1999). Os dados foram categorizados tematicamente e a análise foi ancorada tanto no referencial teórico quanto nos dispositivos legais que orientam a formação e professores no Brasil. Como resultados pode-se afirmar que os PPC investigados possuem currículo inovador, no entanto híbrido, porque mantem a tradicional forma de organização disciplinar, o que se configurou uma contradição, que, no entanto, considera-se aceitável no movimento e momento de mudanças curriculares. Os PPC atendem aos requisitos legais, quanto a carga horária tanto da PCC quanto do ES, mas as práticas não estão suficientes claras, ou uma descrição mais detalhada delas quase sempre não pode ser verificada. Ademais, as concepções de prática quase sempre são difusas, não tem seus fundamentos teóricos claramente declarados.
Tratamento videolaparoscópico para neoplasia de cólon direito: relato de caso
Authors: Pereira Marcela Araújo , Abreu Rone Antônio Alves , Abreu Rebeca Fontoura Morais , Abreu Rone Fontoura , Andrade Gabriela Vellano de , Gallo Fabiana , Mangueira Júnior Pedro Ernesto Alves
Published: October 2020

Objetivo: relatar um caso de neoplasia de cólon direito  em paciente submetido a hemicolectomia laparoscópica no Hospital e Maternidade Dom Orione (HMDO), no estado do Tocantins e discutir seus aspectos clínicos, evolutivos, diagnósticos e terapêuticos, ressaltando a importância do diagnóstico precoce para evitar a progressão da doença. Métodos: Apresenta-se um caso de hemicolectomia direitalaparoscópica em paciente portador de neoplasia de cólon ascendente caracterizando um estudo retrospectivo. Para isto foram utilizados os prontuários localizados no Hospital e Maternidade Dom Orione e da Clínica Gastromed. Resultados: Paciente masculino, 54 anos, procurou a equipe de saúde referindo dor abdominal, moderada em hipocôndrio direito, em cólica, insidiosa, sem irradiação, associada à alteração do hábito intestinal e anemia. Antecedentes: hipertensão arterial, diabetes melito e infarto agudo do miocárdio. Feita a hipótese de neoplasia de cólon, solicitou-se colonoscopia que corroborou com a hipótese inicial. A biópsia identificou um adenocarcinoma tubular moderadamente diferenciado. Os exames laboratoriais se mostravam normais, a não ser pela presença de anemia microcítica e hipocrômica. Paciente submetido a estadiamento: TC de torax e abdome total sem evidências de metástases. CEA: 48,1 (até 3,8 ng/mL). Após ser avaliado pela Cirurgia Oncológica, foi indicado Hemicolectomia direita laparoscópica com linfadenectomia, ileotransverso-anastomose látero-lateral e drenagem da cavidade. Conclusão: Nas condições que foram realizados o presente estudo podemos concluir que a via lapaoscópica se mostrou como um método eficaz para  o tratamento deste paciente portador de neoplasia de cólon ascendente.