bluuebunny/crossref_metadata_2025 huggingface dataset:
An apparent case of brodifacoum toxicosis in a whelping dog
Authors: Fitzgerald Scott D. , Martinez Jennifer , Buchweitz John P.
Published: November 2017

A 7-y-old Weimaraner bitch was presented to emergency service after 3 h of active labor with no puppies produced. Hemoabdomen and hemothorax were present at the time of surgery; prothrombin time (PT) and activated partial thromboplastin time (aPTT) were both found to be within normal ranges. Surgical cesarean section was performed; 4 dead puppies and 5 live puppies were delivered. Because hemostasis was difficult to achieve, a hysterectomy was performed; however, the dog died as the operation was being completed. At autopsy, the pleural cavity contained 1.5 L of unclotted blood; the peritoneal cavity was relatively normal, and no obvious hemorrhage was associated with the surgical sites. All 4 dead fetuses were opened, and their pleural cavities were filled with unclotted blood. An anticoagulant screen was performed, and brodifacoum was identified in the liver of the bitch. This case is unusual in that the PT and aPTT were within reference intervals, but brodifacoum was present in sufficient amounts to potentially result in this dog bleeding to death, and also is suspected to have crossed the placenta and caused hemothorax and death in 4 of 9 puppies in utero.
Pneumocystosis in dogs: meta-analysis of 43 published cases including clinical signs, diagnostic procedures, and treatment
Authors: Weissenbacher-Lang Christiane , Fuchs-Baumgartinger Andrea , Guija-De-Arespacochaga Abigail , Klang Andrea , Weissenböck Herbert , Künzel Frank
Published: November 2017

We evaluated 43 published cases of dogs with confirmed Pneumocystis infection regarding the value of clinical parameters indicating the presence of the disease as well as tools for the detection of the pathogen. The assessed parameters included clinical signs, laboratory findings, results of thoracic radiography, autopsy, histopathology, methods for the detection of Pneumocystis, as well as medical therapy. Pneumocystosis was diagnosed most often in certain breeds (Cavalier King Charles Spaniel, Miniature Dachshund) with a predisposition for impaired immunity. The median age of the dogs was 1 y. Chronic therapy-resistant respiratory signs, such as tachypnea, dyspnea, and cough, along with leukocytosis, neutrophilia, and hypogammaglobulinemia, were the most frequently described clinical and clinicopathologic abnormalities. Pneumocystosis can be masked by coinfections with other respiratory pathogens, and the successful detection of Pneumocystis organisms is of major relevance. Several detection methods have been used in the past, but only a few provide reliable results. In 2017, the cytologic evaluation of Giemsa-stained bronchoalveolar lavage samples is generally used, even if sensitivity is only moderate. More reliable results can be achieved using special stains or sensitive molecular techniques. Fast and reliable detection of Pneumocystis is the essential basis for appropriate treatment and higher survival chances for dogs.
Gangrenous dermatitis in chickens and turkeys
Authors: Gornatti-Churria Carlos D. , Crispo Manuela , Shivaprasad H. L. , Uzal Francisco A.
Published: November 2017

Gangrenous dermatitis (GD) is a disease of chickens and turkeys that causes severe economic losses in the poultry industry worldwide. Clostridium septicum, Clostridium perfringens type A, and occasionally Clostridium sordellii are considered the main causes of GD, although Staphylococcus aureus and other aerobic bacteria may also be involved in some cases of the disease. GD has become one of the most significant diseases of commercial turkeys in the United States. Several infectious and/or environmental immunosuppressive factors can predispose to GD. Skin lesions are considered to be the main portal of entry of the microorganism(s) involved. GD is characterized by acute onset of mortality associated with gross skin and subcutaneous tissue lesions consisting of variable amounts of serosanguineous exudate together with emphysema and hemorrhages. The underlying skeletal muscle can also be involved. Ulceration of the epidermis may be also noticed in cases complicated with S. aureus. Microscopically, necrosis of the epidermis and dermis, and subcutaneous edema and emphysema are commonly observed. Gram-positive rods can be identified within the subcutis and skeletal muscles, usually associated with minimal inflammatory infiltrate. A presumptive diagnosis of GD can be made based on history, clinical signs, and gross anatomic and microscopic lesions. However, confirmation should be based on demonstration of the causative agents by culture, PCR, immunohistochemistry, and/or fluorescent antibody tests.
Isolation and molecular characterization of a urease-negative Actinobacillus pleuropneumoniae mutant
Authors: Ito Hiroya , Takahashi Sayaka , Asai Tetsuo , Tamura Yutaka , Yamamoto Koshi
Published: November 2017

An atypical urease-negative mutant of Actinobacillus pleuropneumoniae serovar 2 was isolated in Japan. Nucleotide sequence analysis of the urease gene cluster revealed that the insertion of a short DNA sequence into the cbiM gene was responsible for the urease-negative activity of the mutant. Veterinary diagnostic laboratories should be watchful for the presence of aberrant urease-negative A. pleuropneumoniae isolates.
Adenosine deaminase activity in pig saliva: analytical validation of two spectrophotometric assays
Authors: Tecles Fernando , Rubio Camila P. , Contreras-Aguilar María D. , López-Arjona Marina , Martínez-Miró Silvia , Martínez-Subiela Silvia , Cerón José J.
Published: November 2017

We validated 2 assays for the measurement of adenosine deaminase (ADA) activity in the saliva of pigs: the Giusti–Galanti manual method (ADA-GG) and a commercial automated assay (Diazyme Laboratories; ADA-D). Intra-assay coefficients of variation (CVs) were <7 and 9%, and interassay CVs were <12 and 5%, for ADA-GG and ADA-D, respectively. Accuracy was measured by 2 methods: recovery and linearity-under-dilution. Recovery was 82.4–106.8% for ADA-GG, and 92.8–107.9% for ADA-D. Serial dilutions showed R2 > 0.95 and 0.99 for ADA-GG and ADA-D, respectively. Linear regression between the methods gave R2 = 0.997 ( p < 0.0001), and a Bland–Altman plot showed a proportional bias of 112 IU/L (95% confidence interval of −99 to 322 IU/L) for ADA-D. No significant differences were observed between the results obtained by either method in saliva or serum. ADA activity was much higher in porcine saliva than in serum. Salivary ADA activity was significantly higher in lame pigs compared to healthy animals. However, serum ADA activity was significantly lower in lame pigs.
Detection of pseudorabies virus by duplex droplet digital PCR assay
Authors: Ren Meishen , Lin Hua , Chen Shijie , Yang Miao , An Wei , Wang Yin , Xue Changhua , Sun Yinjie , Yan Yubao , Hu Juan
Published: November 2017

Aujeszky’s disease, caused by pseudorabies virus (PRV), has damaged the economy of the Chinese swine industry. A large number of PRV gene-deleted vaccines have been constructed based on deletion of the glycoprotein E ( gE) gene combined with other virulence-related gene deletions, such as thymidine kinase ( TK), whereas PRV wild-type strains contain an intact gE gene. We developed a sensitive duplex droplet digital PCR (ddPCR) assay to rapidly detect PRV wild-type isolates and gE gene–deleted viral vaccines. We compared this assay with a TaqMan real-time PCR (qPCR) using the same primers and probes. Both assays exhibited good linearity and repeatability; however, ddPCR maintained linearity at extremely low concentrations, whereas qPCR did not. Based on positive results for both gE and gB, the detection limit of ddPCR was found to be 4.75 copies/µL in contrast of 76 copies/µL for qPCR, showing that ddPCR provided a 16-fold improvement in sensitivity. In addition, no nonspecific amplification was shown in specificity testing, and the PRV wild-type was distinguished from a gE-deleted strain. The ddPCR was more sensitive when analyzing clinical serum samples. Thus, ddPCR may become an appropriate detection platform for PRV.
Influence of coupled fields on free vibration and static behavior of functionally graded magneto-electro-thermo-elastic plate
Authors: Mahesh Vinyas , Sagar Piyush J , Kattimani Subhaschandra
Published: November 2017

In this article, the influence of full coupling between thermal, elastic, magnetic, and electric fields on the natural frequency of functionally graded magneto-electro-thermo-elastic plates has been investigated using finite element methods. The contribution of overall coupling effect as well as individual elastic, piezoelectric, piezomagnetic, and thermal phases toward the stiffness of magneto-electro-thermo-elastic plates is evaluated. A finite element formulation is derived using Hamilton’s principle and coupled constitutive equations of magneto-electro-thermo-elastic material. Based on the first-order shear deformation theory, kinematics relations are established and the corresponding finite element model is developed. Furthermore, the static studies of magneto-electro-elastic plate have been carried out by reducing the fully coupled finite element formulation to partially coupled state. Particular attention has been paid to investigate the influence of thermal fields, electric fields, and magnetic fields on the behavior of magneto-electro-elastic plate. In addition, the effect of pyrocoupling on the magneto-electro-elastic plate has also been studied. Furthermore, the effect of geometrical parameters such as aspect ratio, length-to-thickness ratio, stacking sequence, and boundary conditions is studied in detail. The investigation may contribute significantly in enhancing the performance and applicability of functionally graded magneto-electro-thermo-elastic structures in the field of sensors and actuators.
Association Between Prescription Drug Insurance and Health Care Utilization Among Medicare Beneficiaries
Authors: Alexander G. Caleb , Schiman Cuiping , Kaestner Robert
Published: November 2017

Medicare Part D was associated with reduced hospitalizations, yet little is known whether these effects varied across patients and how Part D was associated with length of stay and inpatient expenditures. We used Medicare claims and the Medicare Current Beneficiary Survey from 2002 to 2010 and an instrumental variables approach. Gaining drug insurance through Part D was associated with a statistically significant 8.0% reduction in likelihood of admission across conditions examined. Reductions were generally greater for younger, healthier, and male individuals. Across all conditions, mean length of stay decreased by 3.2% from a baseline of 5.1 days. Part D was associated with a 3.5% reduction in expenditures per admission, reflecting a decrease of $844 from a mean charge of $24,124 per admission prior to Part D. Thus, Part D was associated with statistically and clinically significant reductions in the probability of admission and length of stay for several common conditions.
Increasing Trends in the Use of Hospital Observation Services for Older Medicare Advantage and Privately Insured Patients
Authors: Lind Keith D. , Noel-Miller Claire M. , Sangaralingham Lindsey R. , Shah Nilay D. , Hess Erik P. , Morin Pamela , Fernanda Bellolio M.
Published: November 2017

Policy and financial pressures have driven up use of observation stays for patients in traditional Medicare and the Veterans’ Affairs Healthcare System. Using claims data (2004-2014) from OptumLabs™ Data Warehouse, we examined whether people in private Medicare Advantage (MA) and commercial plans experienced similar changes. We found that use of observation increased rapidly for patients in MA plans—even though MA plans were not subject to the same pressures as government-run programs. In contrast, use of observation remained constant for people in commercial plans—except for enrollees 65 and older, for whom it increased somewhat. Privately insured patients returning to the hospital after an inpatient stay were increasingly likely to be placed under observation. Our results suggest that observation is rapidly replacing inpatient admissions and readmissions for many older patients in MA and commercial plans, while younger patients continue to be admitted as inpatients at relatively constant rates.
Conceptualising historical privilege: the flip side of historical trauma, a brief examination
Authors: Borell Belinda , Moewaka Barnes Helen , McCreanor Tim
Published: November 2017

Historical trauma is an important and growing area of research that provides crucial insights into the antecedents of current-day inequities in health and social wellbeing experienced by Indigenous people in colonial settler societies. What is not so readily examined is the flip side of historical trauma experienced by settlers and their descendants, what might be termed “historical privilege”. These historic acts of privilege for settlers, particularly those emigrating from Britain, provide the antecedents for the current-day realities for their descendants and the structural, institutional and interpersonal levels of advantage that are also a key feature of inequities between Indigenous and settler. This article theorises an explicit link between historical trauma and historical privilege and explores how the latter may be examined with particular reference to Aotearoa New Zealand. Three core elements of historical trauma are posited as a useful framework to apply to historical privilege.
Bare Nature and the Genocide–Ecocide Nexus—The Conditions of General Threat and the Hope of Cultural Adaptation: The Case of Canada’s Tar Sands
Authors: Arnold Jobb Dixon
Published: November 2017

This article develops the concept of bare nature by examining the interdependent and underlying conditions that make genocidal and ecocidal processes possible. Agamben identifies states of exception as a juridical key to understanding the legitimating logic that facilitate acts of arbitrary exclusion, targeted killing, and the life and death policy decisions that affect large segments of the population. Such regulated, collective precarity constitutes bare life. I argue that bare nature is produced through a parallel process involving ecological “sacrifice zones” that function as states of exception that regulate other-than-human life in service of extreme energy extraction, creating the conditions for ongoing ecological destruction. In the second part of the article, I argue that the local impacts of extreme energy projects like the Canadian Tar Sands contribute to the conditions of bare nature and bare life globally, presenting a “. . . general (transnational) danger threaten[ing] the interests of several states and their inhabitants.” In closing, I turn to the ascendant Indigenous politics in Canada to consider what local cultural survival, global ecological adaptation, and nonsovereign governance models involve in the era of climate change. Indigenous-led politics grounded in land-based normative ethics provide a basis for building alternative futures based on establishing and maintaining conditions of holistic interdependence. Such interdependent conditions will be able to emerge in direct proportion to the extent that the conditions of bare life and bare nature are delegitimated, decommodified, and rendered inoperative.
Round and Round We Go! The Performative Nature of the Roundabout
Authors: Sullivan Thomas , Livingston Christopher
Published: November 2017

The American roundabout is dominated by pragmatic engineering-based literature that emphasizes safety, geometry, cost, energy use, aesthetics, and the mediation of congestion. We, however, propose that the roundabout is a tool for a change in political and social practice in how it promotes a shift in users’ behavior and opens up possibilities for subverting aspects of the automobility discourse. In demonstrating how infrastructure facilitates this change in practice, our research reveals that subtle alterations to the powerful American ideals of individuality, mobility, and freedom occur inside and outside of the roundabout—an unconventional public space. Using aspects of performance theory from the work of Judith Butler, we suggest that these alterations in practice have the potential, over time, to undermine this discourse.
Sign of the times: Workplace mindfulness as an empty signifier
Authors: Islam Gazi , Holm Marie , Karjalainen Mira
Published: November 2017

The rapid emergence of mindfulness programs within organizational settings reflects an amalgam of humanistic, spiritual, and managerial perspectives. While impact studies have focused on effects of mindfulness programs on employees, how such programs are implemented by trainers, managers, and employees and how the mindfulness concept operates within organizations are not well understood. In this study, we draw upon Laclau’s notion of the ‘empty signifier’ to argue that mindfulness programs work to encode oppositional organizational elements, drawing on competing discourses that shape, in practice, how mindfulness evolves within organizations. Through an empirical qualitative study of organizational mindfulness practitioners, we show how practitioners leverage heterogeneous meanings to represent oppositions within organizations, and that in the course of mindfulness programs, these oppositions are framed to align with dominant managerial perspectives. We discuss the ramifications of these findings to understanding the uses of mindfulness for ideological purposes while speculating on the emancipatory possibilities of mindfulness as a solidaristic and collective practice.
‘Her choice of course’: Negotiating legitimacy of ‘choice’ in abortion rights deliberations during the ‘Repeal the Eighth’ movement in Ireland
Authors: Sambaraju Rahul , Sammon Myles , Harnett Frank , Douglas Emma
Published: November 2017

Discourses of ‘choice’ are routinely involved in sexual and reproductive rights’ advocacy. In this article, we offer a discursive psychological examination of how ‘choice’ is oriented to, in online deliberations on the ongoing movement for abortion rights in Ireland. Comment posters treated ‘choice’ as involving outcomes of and motives for choosing, in negotiating legitimacy of women’s rights to choose. These accompanied alternative versions of women, either as independent or as intimately bound up with pregnancy/motherhood, which were flexibly used in negotiation legitimacy of women’s rights to ‘choice’ in abortion practices. Choice advocacy is then situated in particular discursive practices.
Translation and translingual remixing: A young person developing as a writer
Authors: Dewilde Joke
Published: November 2017

Aims and Objectives/Purpose/Research Questions:

This article aims to understand how a young person develops as a translingual writer and which discursive strategies she identifies as important in this process. Neda (pseudonym) has never learnt to write in Turkmen, which is her home language, but is developing as a confident writer in Norwegian, which is the language of the school.

Design/Methodology/Approach:

Situated within a linguistic ethnographic framework, in-depth interviews with the young person were conducted as part of a year-long fieldwork. One interview focused on Neda’s writing experiences in general, and the other two examined how she experienced writing selected poems.

Data and Analysis:

The data for this article are three in-depth interviews with Neda produced over a month’s time, field notes taken in school across that same period, seven poems written at home, and two written in school. The analysis had a joint focus on linguistics and ethnography, identifying core themes.

Findings/Conclusions:

Neda drew on translation and translingual remixing strategies when writing poetry on her own initiative to develop her voice, which indicates a strong sense of agency. In line with a translingual orientation to communication and literacy, these discursive strategies transcend individual languages and involve diverse semiotic resources in situated meaning construction. Both strategies contribute to creating a deeper understanding of the Norwegian language resources in her repertoire and to finding her voice as a transnational young person.

Originality:

Few studies have offered detailed insight into how young people reflect upon their development as translingual writers in their spare time and which strategies they identify as important to do so.

Significance/Implications:

The study contributes to the debate of how teachers can create a space for translingual writing by acknowledging and further developing young people’s own discursive strategies, involving their entire linguistic repertoire.
Clinical decision support systems in hospital care using ubiquitous devices: Current issues and challenges
Authors: Baig Mirza Mansoor , GholamHosseini Hamid , Moqeem Aasia A , Mirza Farhaan , Lindén Maria
Published: November 2017

Supporting clinicians in decision making using advanced technologies has been an active research area in biomedical engineering during the past years. Among a wide range of ubiquitous systems, smartphone applications have been increasingly developed in healthcare settings to help clinicians as well as patients. Today, many smartphone applications, from basic data analysis to advanced patient monitoring, are available to clinicians and patients. Such applications are now increasingly integrating into healthcare for clinical decision support, and therefore, concerns around accuracy, stability, and dependency of these applications are rising. In addition, lack of attention to the clinicians’ acceptability, as well as the low impact on the medical professionals’ decision making, are posing more serious issues on the acceptability of smartphone applications. This article reviews smartphone-based decision support applications, focusing on hospital care settings and their overall impact of these applications on the wider clinical workflow. Additionally, key challenges and barriers of the current ubiquitous device-based healthcare applications are identified. Finally, this article addresses current challenges, future directions, and the adoption of mobile healthcare applications.
Facebook and Twitter vaccine sentiment in response to measles outbreaks
Authors: Deiner Michael S , Fathy Cherie , Kim Jessica , Niemeyer Katherine , Ramirez David , Ackley Sarah F , Liu Fengchen , Lietman Thomas M , Porco Travis C
Published: November 2017

Social media posts regarding measles vaccination were classified as pro-vaccination, expressing vaccine hesitancy, uncertain, or irrelevant. Spearman correlations with Centers for Disease Control and Prevention–reported measles cases and differenced smoothed cumulative case counts over this period were reported (using time series bootstrap confidence intervals). A total of 58,078 Facebook posts and 82,993 tweets were identified from 4 January 2009 to 27 August 2016. Pro-vaccination posts were correlated with the US weekly reported cases (Facebook: Spearman correlation 0.22 (95% confidence interval: 0.09 to 0.34), Twitter: 0.21 (95% confidence interval: 0.06 to 0.34)). Vaccine-hesitant posts, however, were uncorrelated with measles cases in the United States (Facebook: 0.01 (95% confidence interval: −0.13 to 0.14), Twitter: 0.0011 (95% confidence interval: −0.12 to 0.12)). These findings may result from more consistent social media engagement by individuals expressing vaccine hesitancy, contrasted with media- or event-driven episodic interest on the part of individuals favoring current policy.
Understanding children’s perspectives of classroom writing practices through drawings
Authors: Baroutsis Aspa , Kervin Lisa , Woods Annette , Comber Barbara
Published: November 2017

Examining how young children learn to write is increasingly important as global society moves further towards a knowledge economy, where the production of texts of various kinds is an increasingly ubiquitous practice in everyday life and work. While there has been recent policy and practice focus on children’s writing performance in standardised tests, in this article, the authors focus on what can be learned by listening to children’s voices as they are engaged in ‘draw and talk’ methodologies. While children’s drawings have a material reality, they are also representations of children’s perceptions of their experiences with learning to write. In this article, the authors explore the processes, practices and relationships involved in learning to write, depicted in children’s drawings when they are asked to draw themselves learning to write. The authors identify representations of writing, evident in the children’s drawings focusing the relational, the material and the spatial elements of writing.
Helping doctoral students understand PhD thesis examination expectations: A framework and a tool for supervision
Authors: Hodgson David
Published: November 2017

The examination of a PhD thesis marks an important stage in the PhD student journey. Here, the student’s research, thinking and writing are assessed by experts in their field. Yet, in the early stages of candidature, students often do not know what is expected of their thesis, nor what examiners will scrutinise and comment on. However, what examiners look for, expect and comment on has been the subject of recent research. This article synthesises the literature on examiner expectations into a framework and tool that can assist students to understand PhD thesis examination expectations. Suggestions of how this tool may be used as part of a broader supervision pedagogy are offered.
The potential of digital credentials to engage students with capabilities of importance to scholars and citizens
Authors: Miller Kelly K , St Jorre Trina Jorre de , West Jan M , Johnson Elizabeth D
Published: November 2017

Digital credentials (or badges) allow evidence of achievement to be more detailed than is possible through grades, and can be shared more broadly than is possible through the academic transcript. Here, we illustrate the potential use of digital credentials in higher education through sharing an approach that utilised digital credentials to recognise the achievement of students who demonstrate outstanding achievement of specific graduate attributes. More specifically, we explore the potential use of digital credentials to contribute to the development of citizen scholars through engaging students at the course (degree) level, promoting experiential learning and facilitating public sharing. The credentialing strategy described was designed to enhance employability, and the standards and criteria associated with the award were developed in collaboration with industry partners to give students the opportunity to differentiate themselves in the graduate job market. However, student applications, perceptions of the application process and feedback from industry partners who assessed the submissions suggest that an unintended, but positive, outcome of the credentialing strategy was promotion of students’ personal identity and broader social engagement. We suggest that digital credentials at course level could be a useful tool to engage students with graduate attributes, foster graduate identity and develop graduates who are active and engaged citizens.
The semantic and syntactic qualities of paneling in students’ graphic narratives
Authors: Pantaleo Sylvia
Published: November 2017

The overarching purpose of the classroom-based research featured in this article was to explore the development of middle-year students’ visual meaning-making skills and competencies. The research was informed by multimodality and social semiotics, and embraced a sociocultural perspective of literacy and a transactional theory of literature. Over a period of several weeks, Grade 7 students had opportunities to learn about a selection of elements of visual art and design, and some conventions of graphic novels, including paneling. In addition to reading, responding in writing to, and discussing a selection of picturebooks, graphic novels and magazine issues, the students composed their own texts using the medium of comics. In this article I focus on the paneling in the graphic narratives created by seven student participants. The content analysis of the students’ graphic narratives revealed the intentionality of their panel meaning-making, and the semantic and syntactic qualities embodied in their paneling. Excerpts from the students’ interviews revealed how learning about the what, why and how of paneling affected the composing of their work. I conclude the article with a consideration of some pedagogical issues associated with the teaching of paneling and other conventions in the medium of comics.
New territorial rights for sinking island states
Authors: Angell Kim
Published: November 2017

Anthropogenic climate change is an existential threat to the people of sinking island states. When their territories inevitably disappear, what, if anything, do the world's remaining territorial states owe them? According to a prominent ‘nationalist’ approach to territorial rights – which distributes such rights according to the patterns of attachment resulting from people's incorporation of particular territories into their ways of life – the islanders are merely entitled to immigrate, not to reestablish territorial sovereignty. Even GHG-emitting collectives have no reparative duty to cede territory, as the costs of upsetting their territorial attachments are unreasonable to impose, even on wrongdoers. As long as they allow climate refugees to immigrate, receiving countries have done their duty, or so the nationalist argues. In this article, I demonstrate that the nationalist's alleged distributive equilibrium is unstable. When the islanders lay claim to new territory, responsible collectives have a duty to modify their way of life – gradually downsizing their territorial attachments – such that the islanders, in time, may receive a new suitable territory. Importantly, by deriving this duty from the nationalist's own moral commitments, I discard the traditional assumption that nationalist premises imply a restrictive view on what we owe climate refugees.
Introducing conflict as the microfoundation of organizational ambidexterity
Authors: Martin Alexander , Keller Arne , Fortwengel Johann
Published: November 2017

This article contributes to our understanding of organizational ambidexterity by introducing conflict as its microfoundation. Existing research distinguishes between three approaches to how organizations can be ambidextrous, that is, engage in both exploitation and exploration. They may sequentially shift the strategic focus of the organization over time, they may establish structural arrangements enabling the simultaneous pursuit of being both exploitative and explorative, or they may provide a supportive organizational context for ambidextrous behavior. However, we know little about how exactly ambidexterity is accomplished and managed. We argue that ambidexterity is a dynamic and conflict-laden phenomenon, and we locate conflict at the level of individuals, units, and organizations. We develop the argument that conflicts in social interaction serve as the microfoundation to organizing ambidexterity, but that their function and type vary across the different approaches toward ambidexterity. The perspective developed in this article opens up promising research avenues to examine how organizations purposefully manage ambidexterity.
Understanding victim participation in restorative practices: Looking for justice for oneself as well as for others
Authors: Van Camp Tinneke
Published: November 2017

Restorative justice (RJ) promotes a constructive dialogue between the victim of a crime and the offender. Restorative practices have been credited for allowing victims to move on from victimization. This paper goes beyond victim appreciation of RJ and addresses what motivates victims to agree to communicate with their offender. Victim-participants were interviewed at the start of a restorative intervention and again after its conclusion, with the aim of identifying reasons for participation and exploring whether these evolve as a restorative procedure progresses. Discourses reveal that victims hoped that interaction with their adult or young offender would advance insight and healing as well as help the offender. Shifts in motivation over time were only subtle and many respondents manifested prosocial intentions (for example to help the offender) early on.
European penology: The rise and fall of prison population rates in Europe in times of migrant crises and terrorism
Authors: Dünkel Frieder
Published: November 2017

Prison population rates in many European countries have increased until the beginning of the 21st century. Prison overcrowding and questions around the ‘New Punitiveness’ have dominated the discourse. Recently a remarkable drop in prison population rates can be observed, in particular in Central and East European countries (for example, Russia, Belarus, Ukraine, the Baltic states), but also in West European jurisdictions (the Netherlands, Germany and, in the last few years, also Spain). Explanations are not always easy and in most cases this is not the result of a strategic policy but more likely of a sharp decrease in (serious) crime rates. The paper discusses the developments in a European comparative perspective and explores the potentials for a further reduction in prison population rates.
Helical Therapy is Safe for Lung Stereotactic Body Radiation Therapy Despite Limitations in Achieving Sharp Dose Gradients
Authors: Amin Neha P. , Nalichowski Adrian , Campbell Shauna , Hyder Jal , Spink Robyn , Konski Andre A. , Dominello Michael
Published: November 2017

Purpose:

We observed that many of our helical therapy lung stereotactic body radiation therapy plans did not meet the Radiation Therapy Oncology Group (RTOG) recommended R50% (volume of 50% of the prescription dose/planning target volume), which characterizes the steepness of dose fall off. We hypothesized that despite not meeting R50%, helical therapy lung stereotactic body radiation therapy plans would confer similar local control and minimal side effects as previously reported using nonhelical treatment platforms.

Materials and Methods:

We report a retrospective review of all consecutive patients treated off-protocol with stereotactic body radiation therapy for peripheral lung lesions from 2008 to 2013 utilizing helical therapy. Seventy-four patients (81 lesions and 79 plans) were treated with doses ranging from 48 to 60 Gy in 3 to 5 fractions prescribed to the edge of the planning target volume.

Results:

Forty-eight (61%) plans had major deviation from R50%. Only 1 (<1%) plan had a major deviation from the R100%. All plans had > 95% planning target volume coverage by prescription dose, 7(8.6%) plans with 121% to 133% maximum dose, and lung V20 Gy <10% in 70 (89%) plans. With a median follow-up of 4.7 years (95% confidence interval: 4.1-5.3), local control for all patients at 1, 2, and 5 years was 94.6%, 83.4%, and 74%, respectively. For patients with primary stage I-II lung cancer (n = 46), the 1, 2, and 5-year local control: 97.2%, 94.2%, and 86.9%; RC: 97.6%, 82.5%, and 69.5%; and DM: 3%, 16%, and 33.4%, respectively. Patients treated for lung metastases (n = 26) had worse local control at 1, 2, and 5 years: 94.4%, 69.3%, and 55.5%, respectively. Side effects were rare with 2 (3%) patients reporting chest wall pain and 6 (8%) patients experiencing radiation pneumonitis, including 1 patient who had grade 5 radiation pneumonitis.

Conclusions:

Helical therapy delivers a safe and effective lung stereotactic body radiation therapy plan, despite not being able to meet RTOG’s recommended R50 conformality constraint.
Defining, Recognizing, and Reporting Malnutrition
Authors: Elia Marinos
Published: November 2017

Although malnutrition is a common health and social care problem, there is no universal agreement about its definition, prevalence, or method of identification and report. Fifteen definitions of malnutrition were critically examined to assess their variability. They ranged from descriptions of undernutrition alone to under- and overnutrition, with intakes ranging from dietary protein and energy alone to dietary and nondietary sources of all nutrients and energy. Definitions also varied from non-outcome based to those based on functional, physiological, and/or clinical outcomes. Some definitions relied on the pathways by which malnutrition develops, with one apparently requiring loss of fat-free mass. Also examined were nutrition screening tools, diversely developed for detection of malnutrition, management of malnutrition, and prediction of clinical outcomes or health care usage. Their intended use also varied from specific care settings (hospital, community, care homes) to all settings and from specific age groups to all age groups. With all these definitions and tools, there is considerable scope for confusion and misunderstanding. Therefore, to clarify the burden and significance of malnutrition, guidelines for documenting it in routine practice and reporting it in scientific literature are provided.
Nutrition and Lower Extremity Ulcers: Causality and/or Treatment
Authors: Haughey Lauren , Barbul Adrian
Published: November 2017

The association between malnutrition, impaired wound healing, and the presence of chronic wounds has been recognized for a long time. It is widely believed that the lack of adequate nutrition increases the risk of developing wounds which have a great likelihood of progressing to chronicity due to lack of appropriate healing responses. This risk is particularly high in the aging population. For the individual patient, as well as patient populations, the diagnosis of malnutrition has been in dispute; further, there is lack of agreement of when and how to intervene nutritionally in those with wounds or healing deficits. This article examines the relationship of nutritional status with the presence and clinical evolution of leg ulcers in humans, focusing on diabetic and venous leg ulcers; we will further review the effect of nutritional therapy on the outcome of these ulcers.
Self-Control Versus Psychopathy
Authors: DeLisi Matt , Tostlebe Jennifer , Burgason Kyle , Heirigs Mark , Vaughn Michael
Published: November 2017

Self-control and psychopathy are prominent general theories of antisociality that, although present a very similar type of individual, have not often been studied in tandem, and few studies have conducted a head-to-head test of their association with serious delinquency and youth violence. Using a near census of institutionalized delinquents from Missouri, the current study found that both low self-control and psychopathy were significantly associated with various forms of delinquency and severe/chronic delinquency as measured by 90th percentile on the distribution. However, low self-control was associated with more forms of delinquency, and victimization and youth with the lowest levels of self-control were at greatest risk for pathological delinquency relative to those with the most psychopathic personality. Both self-control and psychopathy are essential for understanding the most severe variants of delinquency, and more head-to-head tests are encouraged to assess the strength of criminological theories.
Forced Use of the Paretic Leg Induced by a Constraint Force Applied to the Nonparetic Leg in Individuals Poststroke During Walking
Authors: Hsu Chao-Jung , Kim Janis , Roth Elliot J. , Rymer William Z. , Wu Ming
Published: November 2017

Background. Individuals with stroke usually show reduced muscle activities of the paretic leg and asymmetrical gait pattern during walking. Objective. To determine whether applying a resistance force to the nonparetic leg would enhance the muscle activities of the paretic leg and improve the symmetry of spatiotemporal gait parameters in individuals with poststroke hemiparesis. Methods. Fifteen individuals with chronic poststroke hemiparesis participated in this study. A controlled resistance force was applied to the nonparetic leg using a customized cable-driven robotic system while subjects walked on a treadmill. Subjects completed 2 test sections with the resistance force applied at different phases of gait (ie, early and late swing phases) and different magnitudes (10%, 20%, and 30% of maximum voluntary contraction [MVC] of nonparetic leg hip flexors). Electromyographic (EMG) activity of the muscles of the paretic leg and spatiotemporal gait parameters were collected. Results. Significant increases in integrated EMG of medial gastrocnemius, medial hamstrings, vastus medialis, and tibialis anterior of the paretic leg were observed when the resistance was applied during the early swing phase of the nonparetic leg, compared with baseline. Additionally, resistance with 30% of MVC induced the greatest level of muscle activity than that with 10% or 20% of MVC. The symmetry index of gait parameters also improved with resistance applied during the early swing phase. Conclusion. Applying a controlled resistance force to the nonparetic leg during early swing phase may induce forced use on the paretic leg and improve the spatiotemporal symmetry of gait in individuals with poststroke hemiparesis.
Negative Symptoms and Reward Disturbances in Schizophrenia Before and After Antipsychotic Monotherapy
Authors: Nielsen Mette Ødegaard , Rostrup Egill , Broberg Brian Villumsen , Wulff Sanne , Glenthøj Birte
Published: November 2017

Background. Negative symptoms (NS) are a central part of the symptomatology of schizophrenia, which is highly correlated to the functional outcome. Disturbances of the brain reward system are suggested to be central in the pathogenesis of NS by decreasing motivation and hedonic experiences. In this study, we compared reward-related brain activity in patients improving and not improving in NS after treatment with amisulpride. Methods. Thirty-nine antipsychotic-naive patients and 49 healthy controls completed functional magnetic resonance imaging with a modified monetary incentive delay task. Psychopathology of the patients was characterised with Positive and Negative Syndrome Scale (PANSS), and they were treated with individual doses of amisulpride (mean 271 mg) for 6 weeks, after which the examinations were repeated. Results. Patients improved on positive, general, and total PANSS score after treatment ( P < .001). Fourteen patients had ≥20% improvement of NS, whereas 25 patients improved <20%. At baseline, one-way analysis of variance showed group difference bilaterally in the caudate nucleus and in the right nucleus accumbens (all P < .002), which was caused by decreased reward anticipation activity in the nonimproving patients compared to healthy controls. There was a significant group × time interaction, with the healthy controls and the improvers decreasing and the nonimprovers increasing in reward anticipation activity after treatment, most pronounced in the left caudate nucleus ( P = .001). Discussion. Patients improving in NS score had a less aberrant reward system at baseline, but reward related activity was reduced over time. Patients not improving in NS showed decreased striatal reward-activity at baseline, which improved over time. Whether this is associated with alteration in working memory and reward learning or with pronounced symptoms within specific domains of NS may be addressed in future studies.
Predicting the Risk of Opioid Use Disorder Based on Early Maladaptive Schemas
Authors: Zamirinejad Somayeh , Hojjat Seyed Kaveh , Moslem Alireza , MoghaddamHosseini Vahideh , Akaberi Arash
Published: November 2017

Substance use is a globally devastating social problem. Early maladaptive schemas (EMSs) are inefficient mechanisms leading directly or indirectly to psychological distress. The current study aimed to assess the role of EMSs in predicting opioid use disorder. The cross-sectional study was conducted in 2013 in Bojnurd at northeast of Iran on 60 male opioid users who received Methadone Maintenance Treatment (MMT) and 60 control males. The opioid users were selected randomly from MMT clinics and control subjects were selected and matched with opioid users using demographic variables. The subjects completed the Young Schema Questionnaire-Short Form (YSQ-SF). Except for SS (self-sacrifice), EG (entitlement/grandiosity), US (unrelenting standards), and FA (Failure to Achieve), the mean of other maladaptive schemas in the opioid user group were significantly higher than that of the control group, adjusted for multiple comparisons. Multivariate analysis of variance (MANOVA) indicated significant differences in maladaptive schemas between the two groups. Logistic regression identified that Emotional Deprivation, Mistrust/Abuse, and Unrelenting Standards can predict opioid use. As a result, the risk of opioid-related disorders in people with higher YSQ-SF scores in these schemas is higher. The findings conclude that the existence of underlying EMS may constitute a vulnerability factor for developing opioid use disorders later on in life. Provided the vast amount of scientific literature in evidence-based treatments focusing on EMSs, maladaptive schemas and related core beliefs can be detected and treated in adolescence to prevent the enactment of the schema and psychological distress likely to induce opioid use.
Improving mechanical thrombectomy time metrics in the angiography suite: Stroke cart, parallel workflows, and conscious sedation
Authors: Settecase Fabio , McCoy David B , Darflinger Robert , Alexander Matthew D , Cooke Daniel L , Dowd Christopher F , Hetts Steven W , Higashida Randall T , Halbach Van V , Amans Matthew R
Published: November 2017

Purpose

Earlier reperfusion of large-vessel occlusion (LVO) stroke improves functional outcomes. We hypothesize that use of a stroke cart in the angiography suite, containing all commonly used procedural equipment in a mechanical thrombectomy, combined with parallel staff workflows, and use of conscious sedation when possible, improve mechanical thrombectomy time metrics.

Methods

We identified 47 consecutive LVO patients who underwent mechanical thrombectomy at our center, retrospectively and prospectively from implementation of these three workflow changes (19 pre- and 28 post-). For each patient, last known normal, NIHSS, angiography suite in-room time, type of anesthesia, groin puncture time, on-clot time, recanalization time, LVO location, number of passes, device(s) used, mTICI score, and outcome (mRS) were recorded. Between-group comparisons of time metrics and multivariate regression were performed.

Results

Stroke cart, parallel workflows, and primary use of conscious sedation decreased in-room time to groin puncture (−21.3 min, p < 0.0001), in-room to on-clot time (−24.1 min, p = 0.001), and in-room to reperfusion time (−29.5 min, p = 0.01). In a multivariate analysis, endotracheal intubation and general anesthesia were found to significantly increase in-room to on-clot time ( p = 0.01), in-room to reperfusion time ( p = 0.01), and groin puncture to on-clot time ( p = 0.05). The number of patients achieving a good outcome (mRS 0−2), however, did not significantly differ between the two groups (9/18 (47%) vs 14/28 (50%), p = 0.60).

Conclusions

Use of a stroke cart, parallel workflows by neurointerventionalists, technologists, and nursing staff, and use of conscious sedation may be useful to other institutions in efforts to improve procedural times.
Why Traditional Metrics May Not Adequately Represent Ethnic Minority Psychology
Authors: Syed Moin
Published: November 2017

The first Perspectives on Psychological Science symposium on eminence in psychology focused almost exclusively on “traditional” markers of success (e.g., citation counts, awards, grants). In this essay, I argue that the context of the research and the context of the researchers are crucial components of ethnic minority psychology. First, I describe structural reasons for why ethnic minority researchers might have less impressive traditional markers of success; then, I highlight how the “minority tax” contours the scholarly activities of ethnic minority researchers. Any conceptualization of eminence must take these additional considerations into account.