bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect Of Health Education Video Of Bullying Behavior On Student’s Knowledge
Authors: Hasbyalloh Mochamad , Saraswati Dewi Asri , Atira Atira
Published: June 2024

Background: Bullying is a harmful behavior, especially among elementary school students. Bullying problems and cases that occur must get special attention, so efforts are needed to overcome them. One of the efforts that can be done is through health education using video media.
Methods: This research with Quasi experiment approach with pretest- posttest without control group design. Health education was conducted for 10 minutes and repeated 3 times to test the effect of the intervention. The population in this study were all fifthgrade students at SDN Cisarua, West Bandung Regency, to 70 people. This study used a total sampling technique. This research has been conducted at SDN Cisarua, West Bandung Regency, data collection was taken in March 2024.
Results: there was an effect of health education with video on bullying behavior on student knowledge. After being given health education there are 50 students with good knowledge, 20 students with sufficient knowledge and no students with poor knowledge. The results of the analysis using the marginal homogeneity test obtained a value of p = 0.0001 <0.05, it can be concluded that Ho is rejected, meaning that there is an effect of health education on the knowledge of respondents.
Conclusions: Health education through video media can increase knowledge about bullying on the knowledge of elementary school students.
Influence of Work Posture and Work Duration on the Incidence of Low Back Pain Among Batik Artisans: a Cross-sectional Study
Authors: Pamungkas Megistra , Pratama Susilo Budi , Fatharani Lukman Faishal
Published: June 2024

Background: Batik artisans, particularly those involved in the "nyanting" process, are susceptible to lower back pain due to non-ergonomic working postures. These craftsmen sit for long durations as they meticulously apply wax to fabric. They utilize dingklik, which compels them to sit in a slightly hunched position. The repeated adoption of such postures can heighten the risk of lower back pain. This research aims to investigate the relationship between work posture, years of service, and the incidence of low back pain among "nyanting" batik artisans in Pulorejo Village
Methods: This observational analytical research employed a cross-sectional approach with 42 "nyanting" batik artisans chosen through a total sampling technique. Conducted in Pulorejo Village in January 2024, the research assessed work posture using the Rapid Entire Body Assessment (REBA) instrument, while the occurrence of low back pain was evaluated through history taking and physical examination. Statistical analysis was performed using IBM SPSS version 25.0 software.
Results: A significant positive correlation was found between years of service and the occurrence of low back pain (LBP) (p=0.002; r=0.471). The risk of LBP increases with the length of service. Additionally, there was a significant positive correlation between working posture, as indicated by the REBA score, and the occurrence of LBP (p=0.010; r=0.395). A higher REBA score corresponds to a greater risk of LBP.
Conclusions: the Years of service and the working posture were associated to  the incidence of low back pain (LBP) among "nyanting" batik artisans in Pulorejo Village.
Relationship Between Self-Management and Health Behavior of Hypertension Patients in Romana Tanjung Anom Clinic
Authors: Gultom Stefi Kristina , Novitarum Lilis , Simanullang Murni Sari Dewi
Published: June 2024

Background: Health problems in patients at the  Romana Tanjung Anom clinic arise as a result of health behaviors that have a negative impact. Health problems are the result of human behavior in interacting with themselves and their environment, both biological, psychological, socio-cultural, and even political environments. Efforts to overcome health problems are by changing health behavior in self-management. This study aimed to find out whether there is a relationship between self-management and health behaviour behavior of hypertensive patients.
Methods: Methods of the research conducted was correlational with a cross-sectional approach, involving 79 respondents.The sampling method employed was purposive sampling.Researchers used the first 2 questionnaires, namely self-management with 40 questions.The second questionnaire is behavior with 17 questions. Questionnaires are filled out and submitted offline or directly at the place of research. This study used bivariate analysis and with statistical tests of spearman rank.
Results: The result of the study were obtained  Self-management of hypertensive patients at Romana Tanjung Anom Clinic had good self-management of 47 respondents (59.5%) from 79 respondents. The health behavior of hypertensive patients at Romana Tanjung Anom Clinic in 2023 has good health behavior of 68 respondents (86.1%) from 79 respondents. There is a significant relationship between self-management and health behavior hypertensive patients at Romana Tanjung Anom Clinic in 2023 with p-value=0.019 (p<0.05) and a correlation of 0.264.
Conclusion: The conclusion of this study is that there is a significant relationship between self-management and health behavior of hypertensive patients at Romana Tanjung Anom Clinic  and have good health behaviors
Analysis of Social Factors on Immunization Refusal in Jungkat Village
Authors: Andika Andika , Rupita Rupita , Marini Marini , Bakri Abu Rizal , Ramada Triadi , Sabil Ibnu , Kurniawan Edi
Published: June 2024

Background: Immunization is one of the most effective and efficient health intervention programs to prevent various diseases in children. But there are still refusals of immunization in some areas in West Kalimantan, one of which is in Jungkat Village. The low number of fully immunized children in Jungkat Village is a serious problem. As a result of not being immunized, dangerous diseases that can be prevented by immunization still threaten children in Jungkat Village. This study aims to understand and identify the factors of refusal of complete basic immunization in Jungkat Village, Mempawah District, West Kalimantan.
Methods: This research used a descriptive qualitative approach.  The number of participants in this study was six people who were selected using purposive sampling method. Of the six people, consisted of the head of the Jungkat Health Center, posyandu officers, and three mothers who had toddlers aged 0-24 months.
Results: Traditional beliefs and experiences: people in Jungkat village believe that bad things will happen after immunization, family support: without family support, mothers in Jungkat village will be less motivated to participate in the immunization program, parents. There are parents who do not understand why immunization is important for their children's health.
Conclusions: Research on the factors of refusal of basic immunization in Jungkat Village, found that the factors of belief in tradition and community experience, community experience, family support, and parental knowledge greatly influenced community attitudes towards immunization.
The Microbiome-Brain Axis: Exploring the Gut-Brain Connection in Neurological Disorders
Authors: Mehta Kartik
Published: June 2024

The association and interaction between the central nervous system (CNS) and enteric nervous system (ENS) is well established. Essentially ENS is the second brain, as we call it. We tried to understand the structure and function, to throw light on the functional aspect of neurons, and address various disease manifestations. We summarized how various neurological disorders influence the gut via the enteric nervous system and/or bring anatomical or physiological changes in the enteric nervous system or the gut and vice versa. It is known that stress has an effect on Gastrointestinal (GI) motility and causes mucosal erosions. In our literature review, we found that stress can also affect sensory perception in the central nervous system. Interestingly, we found that mutations in the neurohormone, serotonin (5-HT), would result in dysfunctional organ development and further affect mood and behavior. We focused on the developmental aspects of neurons and cognition and their relation to nutritional absorption via the gastrointestinal tract, the development of neurodegenerative disorders in relation to the alteration in gut microbiota, and contrariwise associations between CNS disorders and ENS.
Drug Repurposing: Finding New Therapeutic Uses for Existing Pharmaceuticals
Authors: Nair Rahul
Published: June 2024

This paper explores the concept of drug repurposing as a viable strategy for discovering new therapeutic uses for existing pharmaceuticals. It examines various approaches to drug repurposing, including serendipitous discoveries, target-based screening, pathway analysis, computational methods, drug combination therapy, and clinical data mining. The paper discusses the advantages of drug repurposing over traditional drug development and highlights successful examples of repurposed drugs. It also addresses challenges and future directions in the field of drug repurposing.
Neuroplasticity and Rehabilitation: Harnessing Brain Plasticity for Stroke Recovery and Functional Improvement
Authors: Singh Shailendra
Published: June 2024

This paper provides a comprehensive review of the current understanding of neuroplasticity and its application in stroke rehabilitation. Stroke remains a leading cause of disability worldwide, often resulting in motor, sensory, and cognitive impairments. Neuroplasticity, the brain's ability to reorganize and adapt in response to experience and injury, offers promising avenues for recovery. This review discusses key principles of neuroplasticity and explores various rehabilitation strategies aimed at harnessing its potential for stroke recovery. Topics covered include early intervention, task-specific training, intensity and repetition, constraint-induced movement therapy, multimodal approaches, environmental enrichment, and neurostimulation techniques. Additionally, the paper discusses emerging research directions and challenges in optimizing neuroplasticity-based rehabilitation approaches. Understanding the role of neuroplasticity in stroke recovery can inform the development of more effective rehabilitation interventions and improve outcomes for individuals affected by stroke.
Marketing Programs of Modern Pharmaceutical Enterprises
Authors: Izmailov Airat ,   Povolzhskiy State University of Telecommunications & Informatics, Astratova Galina , Ostrovsky Arseny ,   Samara State Medical University,   Ural Federal University named after the first President of Russia B.N. Yeltsin,   Ural Law Institute of the Ministry of the Interior of the Russian Federation,   Ural Federal University named after the first President of Russia B.N. Yeltsin
Published: July 2024

The article is devoted to comparative analysis of the experience of marketing programs development used by pharmaceutical industry organizations operating both in Russia and in foreign countries. The relevance of the chosen topic is explained by the fact that, while trading in specific goods, it is important for the pharmaceutical industry to develop and implement the program containing the main aspects of product promotion, attracting consumers, and increasing the efficiency growth. The research methods are characterized by comparative analysis and information synthesis. The purpose of the study is to summarize the experience of domestic and foreign pharmaceutical companies in marketing programs development, taking into account the specifics of the main products. The results of the study are identification of the main tools used to attract and retain customers. The obtained results can be used by pharmaceutical companies in Russia to improve the quality of interaction with potential customers using the Internet, which determines the general vector of marketing programs for the development of pharmaceutical industry organizations. In the work domestic pharmaceutical industry is characterized as an object of marketing research. Development features of Russian pharmaceutical sector are highlighted, and theoretical analysis of marketing program concept is carried out. The author's interpretation of marketing program concept for pharmaceutical enterprise is proposed, and the stages of marketing program formation are highlighted. Peculiarities and general features of marketing program formation for domestic and foreign manufacturers are determined.
ANÁLISE DA PRODUÇÃO SOBRE A SEGURANÇA DO PACIENTE NA ATENÇÃO PRIMÁRIA À SAÚDE
Authors: Marilene Ribeiro Almeida Costa
Published: June 2024

Objetivo: analisar o nível da produção sobre a segurança do paciente na atenção primária à saúde. Métodos: foi realizada uma revisão integrativa de literatura, foram analisados artigos recuperados por meio das bases de dados secundários Biblioteca Virtual em Saúde, Literatura Latino-Americana e do Caribe em Ciências da Saúde, Scientific Eletronic Library Online e Sistema Online de Busca e Análise de Literatura Médica a partir dos descritores segurança do paciente, atenção primária à saúde e estratégia saúde da família, a partir dos operadores booleanos. Resultados: evidencia-se que a temática segurança do paciente ainda está fortemente limitada a estudos conduzidos no ambiente hospitalar apenas, o qual limita igualmente as práticas sobre segurança do paciente na atenção primária, há esforços governamentais para mudar esse cenário, uma vez que no ano de 2017 a segurança do paciente foi introduzida na política nacional de atenção básica, mas, exige-se esforços das gestões locais e profissionais que atuam no sistema de saúde brasileiro. Conclusão: os resultados do presente estudo indicam que o nível da produção sobre a segurança do paciente na atenção primária à saúde é insipiente.
COLANGIOGRAFIA INTRAOPERATÓRIA NA PREVENÇÃO DE LESÃO DO DUCTO BILIAR EM COLECISTECTOMIA LAPAROSCÓPICA
Authors: Pedro Alves de Sousa
Published: June 2024

Este estudo de revisão examina a segurança da colecistectomia videolaparoscópica (CVL). Examinar protocolos e métodos tradicionais, considerar a importância de novas tecnologias e enfatizar os desafios ainda existentes para reduzir as lesões das vias biliares (LVB). O artigo examina as opções para maximizar a segurança do paciente na CVL por meio de uma análise abrangente de práticas baseadas em evidências e avanços de ponta . O texto enfatiza as principais medidas de segurança, como a adesão à Visão Crítica de Segurança (VCS), a implementação da colangiografia intraoperatória (CIO) e o cumprimento da regra STOP. Além disso, é discutido como novas tecnologias, como cirurgia guiada por fluorescência (CGF) e colecistectomia robótica (CAR), podem melhorar a segurança. Para refinar continuamente os padrões de segurança na CVL, o artigo conclui enfatizando a necessidade de uma abordagem multifacetada que combine técnicas consolidadas com avanços tecnológicos.
ASPECTOS CRÍTICOS DE CIRURGIAS DE EMERGÊNCIA EM CRIANÇAS COM DOENÇAS ENDÓCRINAS CRÔNICAS
Authors: Lucas Dambrós
Published: June 2024

O objetivo é determinar o perfil das internações de crianças e adolescentes no município de João Pessoa-PB devido a doenças crônicas. O estudo é descritivo e quantitativo, utilizando um desenho transversal. No município de João Pessoa-PB, o Hospital Universitário Lauro Wanderley (HULW) e o Complexo de Pediatria Arlinda Marques (CPAM) foram os locais onde o estudo foi desenvolvido. A amostra continha 239 crianças e adolescentes que apresentavam uma doença persistente. Os pesquisadores obtiveram um instrumento validado por Araújo (2019), que foi preenchido com o cuidador principal da criança ou adolescente internada. Quando os dados foram preenchidos, eles foram inseridos em uma base de dados para que pudessem ser compilados e interpretados. Resultados e discussão: Asma, cardiopatia congênita, fibrose cística, púrpura trombocitopênica idiopática e síndrome nefrótica foram as cinco principais causas de internação no HULW. Além disso, asma, cardiopatia congênita, epilepsia, neuropatia crônica e púrpura trombocitopênica idiopática foram incluídas no CPAM. As causas mais comuns em todos os hospitais eram as mesmas. Conclusão : Os dados encontrados podem revelar coisas que os órgãos públicos não estavam vendendo ou que não estavam fazendo . Tais dados demonstraram o enorme problema de cuidadores, crianças e adolescentes que ainda não estão sendo atendidos no sistema de saúde.
INFLUÊNCIA DAS INUNDAÇÕES NA SITUAÇÃO DE SAÚDE DA COMUNIDADE DO GOGÓ DA EMA EM ITABUNA, BA: DESAFIOS E RESPOSTAS COMUNITÁRIAS
Authors: Vanessa Souto Paulo  , Joana Maria Soares dos Santos  , Gilvia Queiroz Santos  , Josué Alves Matos das Virgens  , Prudence Secchin de Sousa Vaz Sampaio Ribeiro  , Vanner Boere  , Ita de Oliveira e Silva
Published: June 2024

Introdução: A cidade de Itabuna é frequentemente sujeita a inundações severas, um fenômeno que tem impactado significativamente a vida e a saúde de suas comunidades, em especial a comunidade do Gogó da Ema. Objetivo: Avaliar a influência das inundações na situação de saúde da comunidade, identificando desafios enfrentados e respostas comunitárias. Métodos: Estudo transversal descritivo utilizando métodos quantitativos e qualitativos. Foram realizadas 109 entrevistas com moradores entre dezembro de 2023 e março de 2024, usando um questionário semiestruturado abordando dados sociodemográficos, condições de moradia e saúde. A análise dos dados foi realizada utilizando os softwares Jamovi e Minitab. Resultados: Observou-se que 100% das casas entrevistadas foram atingidas pelas inundações em 2021 e 81,8% em 2022. A maioria das casas utiliza água encanada (90,9%) e é conectada à rede de esgoto municipal (76%), mas ainda há deficiências significativas em saneamento e purificação da água. A prevalência de sintomas respiratórios, como tosse e falta de ar, foi significativa, correlacionada com a umidade e as condições insalubres resultantes das inundações. Além disso, 26,7% dos entrevistados relataram casos recentes de diarreia. Conclusão: As inundações têm um impacto profundo na saúde física e mental dos moradores, exacerbando problemas respiratórios e diarreicos. Melhorias na infraestrutura de saneamento e controle de vetores são cruciais. Recomenda-se a implementação de políticas públicas integradas, incluindo educação em saúde e preparação para desastres, para aumentar a resiliência comunitária. As lições aprendidas podem informar políticas de saúde e planejamento urbano em áreas com desafios similares.
PATIENT-SELECTION PROGRAM TRAINING FOR MENTAL HEALTH CADRES IN DEVELOPING INDEPENDENT BUSINESS FOR THE FAMILY
Authors: Algristian Hafid , Fitriyah Fifi Khoirul , Fasya Abdul Hakim Zakkiy , Bistara Difran Nobel , Putri Rahmadaniar Aditya , Bariyah Khadijah Khairul
Published: June 2024

People with severe mental disorder (PSMD; Orang Dengan Gangguan Jiwa, ODGJ) are a vulnerable group of people who experience loss of their rights to life because of their mental limitations, namely the right to work and earn an income independently. In previous activities, there was an opportunity for PSMD to recover through a series of training. To achieve recovery, it is necessary to hold a patient selection program so that patients who take part in the training series are not in the acute phase. Mental health cadres who are close to the community have a big role in determining which PSMD will then take part in entrepreneurship training activities. Therefore, mental health cadres need to deepen their insight into mental disorders and increase their empowerment in patient selection programs for PSMD. This activity aims to increase the understanding of mental health cadres regarding mental disorders and increase their empowerment in implementing patient selection programs for PSMD. The method used was by conducting outreach to mental health cadres regarding the topic of mental disorders as well as providing patient selection program training to mental health cadres. Before counseling and training, a 10-minute pre-test was conducted for the participants, then continued with an outreach and training session as well as questions and answers and discussions for approximately 60 minutes, and at the end a 10-minute post-test was carried out. The results showed an increase in pre-test and post-test data on the topic of mental disorders as well as an increase in empowerment by mental health cadre participants in carrying out patient selection programs. Community service activities regarding patient selection program training for mental health cadres in developing independent businesses for PSMD families in the Gresik district have provided improvements to mental health cadres, namely in the form of increased insight regarding mental disorders and increased empowerment in carrying out patient selection programs for PSMD.
EDUCATION OF EARTHQUAKE ALERT APPLICATION AT PGRI MIDDLE SCHOOL BANTUR MALANG
Authors: Dewanti Nisa , Diana Meli , Riesmiyatingdyah Riesmiyatingdyah , Apryanto Frengki , Zunaedi Rosly
Published: June 2024

The Earthquake Alert Application Socialization Activity given to teachers at PGRI Middle School Bantur Malang is a form of community service in the form of delivering material and socializing the use of the Earthquake Alert Application as a guide on how to rescue when an earthquake occurs. Implementation of socialization activities on August 25 2023 at PGRI Middle School Bantur Malang. The target of this outreach activity is all teachers at PGRI Middle School Bantur. Before carrying out extension activities, there is an activity preparation process for approximately six weeks before carrying out the activities, starting from making applications to submitting permits to related parties. As a form of evaluation, this activity has attended by eight teachers, the participants participated in the activity very enthusiastically, and all participants were able to operate the application well.
FLAVONOIDS FOR ANTI-HYPERURICEMIA: A LITERATURE REVIEW
Authors: Putri Diah Pitaloka , Putra Kusuma Wijaya Ridi
Published: June 2024

Background: Hyperuricemia is a condition on the level of uric acid in the blood increases, it is more than 6.0 mg/dL in women and more than 7.0 mg/dL in men and is currently a public health problem because of its increasing prevalence. Hyperuricemia is believed to have contributed to an increased risk of mortality and morbidity associated with various diseases such as metabolic syndrome, kidney disease, cardiovascular disease, etc. Flavonoids in plants can be used to help treat hyperuricemia due to it is believed to have low side effects.
Objective: The aim of this article was to review the effect of flavonoids on plants as anti-hyperuricemia.
Design: The design used in preparing this manuscript is an integrative review by reviewing articles on the impact of flavonoids as anti-hyperuricemia.
Data Sources: Sources of information were obtained from research articles from 2004-2023 which were accessed through PubMed, Scopus, Sciendirect, SpringerLink, and Google Scholar.
Review Methods: In the process of selecting articles to ensure the quality of the articles used in preparing this article, the authors used the PRISMA method.
Results: In this article, 15 in vivo studies related to the effect of plants containing flavonoids (kaemferol, luteolin, apigenin, rutin quercetin, morin, butein, vitexin, etc.) on reducing uric acid levels by various mechanisms from previous studies.
Conclusion: Based on several studies reported that flavonoids have an effect on lowering uric acid levels by inhibiting xanthine oxidase (XO) activity, affecting the expression of uric acid transporters in the kidneys which contribute to the increase of excretion of uric acid in urine.
EFFECT OF KANGAROO MOTHER CARE (KMC) ON THE FORMATION OF MATERNAL-INFANT ATTACHMENT BETWEEN MOTHERS AND PREMATURE BABIES: A LITERATURE REVIEW
Authors: Zubaidah Zubaidah , Safitri Ayu Diah
Published: June 2024

Background: Nursing care of premature babies in the Neonatal Intensive Care Unit (NICU) setting can inhibit the maternal-infant attachment. One of the evidence-based interventions for premature babies is Kangaroo Mother Care (KMC). KMC needs to be further studied and researched through a review of previous articles to ensure the effectiveness of that implementation. However, there is a very limited review that specifies the effect of KMC on the formation of maternal-infant attachment. Objective: This study was conducted to assess the effect of KMC on maternal-infant attachment between mothers and premature babies. Design: The design of this study uses a literature review. Data Sources: Initial searches of journal articles were performed on the Pubmed, ScienceDirect, and CINAHL search databases. The study found 676 articles but only 7 journal articles that met the search inclusion criteria. Review Methods: A literature review procedures were used to collect library data, reading and taking notes, as well as critical assessment of managing research materials. Results: The results of this review showed that KMC has been shown to have a positive impact on improving attachment status and resulting in a lower risk of bonding failure between mothers and premature babies. Conclusion: It is recommended that health workers can provide treatment using KMC as an intervention to improve the formation of maternal-infant attachment between mothers and premature babies. The policies related to the implementation of KMC as standard operating procedures are also important.
INCREASING KNOWLEDGE OF MIDWIFERY STUDENTS ABOUT FLOOD DISASTERS USING THE JIGSAW LEARNING METHOD
Authors: Oktarina Mika , Eliagita Choralina , Absari Nuril , Rahmawati Ida , Utami Yustri
Published: June 2024

Background: Not having had direct experience in dealing with disasters means that students are not ready to be prepared, so disaster education using a jigsaw learning method is needed.
Objectives:  This research aims to study the effect of the jigsaw learning model on knowledge of flood disasters in level 3 students in the STIKES TMS undergraduate midwifery study program.
Methods:     The research design used pre-experimental with one group pretest and post test design.  The population of this study were all third year undergraduate midwifery students at STIKES TMS totaling 30 (total sampling) using the Wilcoxon test.
Results: The knowledge of third level midwifery students at STIKES TMS before the jigsaw method was known to be less than 6 people, 15 people were sufficient and 9 people were good.  The knowledge of third level midwifery students of STIKES TMS after the jigsaw method was found to be 3 people lacking, 5 people sufficient and 22 people good
Conclusion: The p value = 0.000 means that there is an influence of the jigsaw learning method on knowledge of flood disasters in third year undergraduate midwifery study programs at STIKES TMS Bengkulu
Distribuciones de máxima entropía, incremento de aleatoriedad y teoremas límite en probabilidad
Authors: Gordienko Evgueni , Minjárez Sosa Jesús Adolfo
Published: June 2024

En este artículo se explora el concepto de distribuciones de máxima entropía en el contexto de la teoría de la probabilidad. Se analiza la relación entre incremento en la aleatoriedad, máxima entropía y los teoremas límite en probabilidad, proporcionando un enlace entre la incertidumbre estadística y los principios termodinámicos, en particular con la segunda ley de la termodinámica. En términos generales, veremos que el aumento en la entropía va acompañado con el aumento de la incertidumbre o aleatoriedad en un sistema, lo cual puede ser interpretado como una transición a un estado de equilibro termodinámico. Finalmente algunos de estos resultados se presentan en el marco de la teoría de la información.
Coagulante orgánico a base de Tamarindus índica como tratamiento terciario en aguas residuales
Authors: Ruiz Murillo Eduardo Ariel
Published: June 2024

La protección de los recursos hídricos a través de la implementación de procesos de tratamiento de las aguas residuales que son depositadas en estos se ha convertido en un gran reto para la región centroamericana, dado que cada vez es más notoria la eutrofización de los cuerpos de agua derivado de las descargas de agua residual con significativas concentraciones de nitrógeno y fósforo. Derivado de lo anterior, se ha estado realizando diversas investigaciones para proponer mecanismos locales que permitan reducir estos nutrientes, siendo uno de ellos la utilización de la semilla de Tamarindus índica debido a que su composición química se ha encontrado ácido glutámico lo cual según Campos y colaboradores (2003) son responsables de su capacidad de coagulación. En este estudio se analizó el desarrollo de un coagulante a base de la semilla de Tamarindus índica para evaluar su capacidad de reducción de fosfato-P y nitrato-N en aguas residuales proveniente del tratamiento secundario, obteniéndose una reducción máxima de 46.42±24.06% para el fosfato-P y de 37.87±29.61% para el nitrato-N, aplicando dosis de 120 y 95 miligramos de coagulante orgánico respectivamente. Por lo anterior la semilla de Tamarindus índica puede ser una opción para reducir el fosfato y nitrato cuando se requieran reducciones menores a 50%.
Opportunities and challenges of integrating HIF-1 into clinical practice for cancer treatment
Authors: Vasileiou Maria , Tsianava Christina , Charalampos Diamantoudis Sotirios , Mazneva Teodora , Giortsiou Kleio
Published: July 2024

The Warburg effect is one of the most studied mechanisms involved in cancer progression. It refers to the increased glucose uptake by cancer cells through aerobic glycolysis, instead of the Krebs cycle that takes place under normal conditions, followed by lactic acid fermentation. This mechanism is regulated by hypoxia-inducible factor-1 (HIF-1), a transcription factor that regulates the expression of genes responsible for the synthesis of proteins involved in glucose metabolism. Overexpression of HIF-1 has been linked to the Warburg effect. While several HIF-1-targeted strategies have been investigated, the majority have proven to be unsuccessful, especially in cases of aggressive tumors with hypoxic tumor microenvironments. Current strategies expand beyond conventional chemotherapeutic agents and include chemodynamic therapy, radiation therapy, and immune checkpoint molecules. The aim of this literature review is to highlight the implication of HIF-1 in the Warburg effect and the limitations that render cancer treatment less effective.
A Study of Drug Uses Evaluation of Anti Anemic Drugs in Pregnancy Patients at a Tertiary Care Teaching Hospital
Authors: - Rahul s , - Nayeem
Published: June 2024

Background: Anemia is a common condition among pregnant women and can have adverse effects on both maternal and fetal health. The use of antianemic drugs in pregnancy is essential to manage and treat anemia, but their efficacy and safety remain a topic of significant interest and concern.
Objective: To study the drug use evaluation of anti anemic drugs in pregnancy patients in hospital. Cases were collected from OBG ward
Methodology: A prospective observational study was conducted for three months from December 2023 to February 2024 in Navodaya medical college, hospital & research centre with a sample size of 100. Data were collected from OBG ward.
Result: Among the 100 cases collected, most of the anemic patients were in the age group of (18-25) years. Most common anti anemic drugs prescribed in anemic patients are Ferrous ascorbate and Folic acid.
Conclusion: in evaluation of antianemic drug use in pregnancy is essential for ensuring the effective management of maternal anemia while minimizing risks to the fetus. By assessing prescribing practices, safety considerations, and adherence to clinical guidelines, healthcare providers can enhance the quality
of care provided to pregnant women and contribute to better maternal and child health outcomes
Effectiveness of Peer Tutoring in Enhancing Fundamental Arithmetic Operations
Authors: - Jacqueline L. Socorin MAEd , - Catherine J. Oyao MAEd
Published: June 2024

This study utilized the descriptive correlational design to determine the effectiveness of Peer tutoring in enhancing Fundamental Arithmetic Operations of the fifty-two (52) learners in Grade III-Lily and Jasmine of U-og Elementary School, Inabanga, Bohol. Most of the respondents were at the age of 9 and majority were female. A researchers-made survey questionnaire was used as tool in gathering the data. The gathered data were tallied and analyzed using frequency count, simple percentage, weighted mean, and Pearson Product Moment Correlation Coefficient to test the relationship between Peer tutoring and Fundamental Arithmetic Operations. Results showed that the computed r-value 0.413782 was higher than the critical r-value 0.2732 at 0.05 level of significance with 50 degrees of freedom, so the null hypothesis was rejected. Therefore, there was a significant relationship between Peer tutoring and Fundamental Arithmetic Operations which implied that peer tutoring is one of the strategies that may help and assist learners in enhancing fundamental arithmetic operations.
Androgenesis in Hot Pepper by Chilli Anther Culture
Authors: - Komal Purushottam Kharad , - Sarosha Khan
Published: June 2024

In vitro androgenesis techniques play a key role in the quick generation of fully homozygous lines. This work's goal was to put the procedure for producing androgenic embryos in hot pepper populations into practice. A number of variables can affect androgenetic success, including the types and quantities of carbohydrate sources and the nature of the nutritional medium. Different sugar types were tested at different doses in anther culture of pepper to elucidate their influence on the yield of androgenesis. In this study, sucrose was used as a source of sugar, Murashige & Skoog (1962-MS) medium, silver nitrate (AgNO3), naphthaleneacetic acid (NAA), BAP and one breeding lines of pepper were used to know the genotypic effects on haploid embryo formation. It was found that one of the key elements influencing pepper anther and microspore culture success is genotype. Also, microspore stage and the cold treatment of flower bud responsible for the success of embryo formation. This embryo formation frequency has been calculated according to the results that were generated in one month and the frequency of embryo formation is 0.7%.
Application of Artificial Intelligence in HRM
Authors: - Dr.Sriparna Guha , - Anija Chandra
Published: June 2024

Accurate data collection and analysis are crucial in today's competitive industries for the growth and day-to-day operations of businesses. Artificial intelligence facilitates faster and more efficient work completion in the industry. Artificial intelligence is making its way into a number of departments, including marketing, finance, human resources, and production. The objective of the paper is to find out the effectiveness of AI in business decision regarding recruitment, selection and training practices.
Factors Associated with Hygiene Practices among Breastfeeding Mothers Attending Maternal and Child Health Clinic at Mandera County Referral Hospital, Kenya
Authors: - SADAM ABDI MAALIM , - DOMINIC MOGERE , - DIANA NJUGUNA
Published: June 2024

Hygiene practices play an important role in the well-being and health of both breastfeeding mothers and their infants. Poor hygiene practice might contribute to spread of infection and disease, posing significant risks to the health of the mother-infant dyad. Understanding the factors associated with hygiene practices among breastfeeding mothers is essential for designing effective interventions to improve hygiene behaviors and promote better health outcomes. The study objective was to identify the factors associated with hygiene practices among breastfeeding mothers attending Maternal and Child Health (MCH) clinic at Mandera County Referral Hospital. By examining these factors, the study aimed to inform targeted interventions that promote proper hygiene practices among breastfeeding mothers and ultimately improve maternal and child health in the region. This study used a cross-sectional descriptive research design, utilizing both qualitative and quantitative data collection techniques. A sample of 360 breastfeeding mothers attending the MCH clinic at Mandera County Referral Hospital were recruited. Quantitative data was collected through structured questionnaires. Additionally, Focus Group Discussions (FGDs) and in-depth interviews were used to collect qualitative data. Quantitative data was analyzed using SPSS Version 26 while qualitative data was analyzed thematically. Findings revealed varying levels of knowledge and adherence to hygiene practices among participants. Socio-cultural beliefs, economic constraints, and access to resources were identified as key determinants influencing hygiene behaviors. Limited access to clean water, sanitation facilities, and hygiene products posed significant challenges, particularly in rural communities. Healthcare providers played a crucial role in promoting hygiene practices but faced limitations in resource availability and infrastructure. Recommendations include integrating hygiene education into routine clinic visits, enhancing access to water and sanitation infrastructure, and strengthening community-based initiatives. Addressing socio-economic disparities and cultural norms is essential to improving hygiene practices and maternal and child health outcomes in Mandera County. Collaborative efforts involving policymakers, healthcare providers, and community stakeholders are needed to implement effective interventions and address the identified barriers.
Effectiveness of Mental Health Promotion Policies and Programs of State Universities
Authors: - Jessa Marie L Alvarez
Published: June 2024

The Mental Health Law, also known as RA 11036, is the approved legal basis for promoting awareness about mental health. It mandates every local government unit and academic institution to create its programs following the general guidelines set by the Philippine Council for Mental Health created under this law. Moreover, because there is a growing number of adolescents suffering from mental health problems, there is an excellent need for universities to take care of students’ mental health. This study primarily seeks to assess the effectiveness of mental health promotion policies and programs in the state universities of Region 2 in the Philippines and to know if there are significant differences between the respondents’ assessed effectiveness when grouped according to their profile variables: students (age, sex, years of stay, course) and implementers (educational attainment, years of experience, number of seminar/training & employment status). The study utilized a quantitative method, specifically using a survey questionnaire. Sampling was done through stratified and convenience sampling. The study’s results show that both students and implementers rated the efforts of the state universities in implementing mental health promotion policies and programs as “effective.” Implementers consistently gave higher ratings than students. Moreover, significant differences were present among the respondents’ assessed effectiveness of the academic institutions when grouped according to university, sex, and course/program. Regarding years of stay, only the indicator “facility access and referral mechanisms for psychosocial support” received a significant difference rating.
अशोक के वृहत् शिलालेखों में वर्णित ‘लोक जीवन’
Authors: - Dr. Garima Bharti
Published: June 2024

शोधसार :- चौथी से दूसरी शताब्दी ईसा पूर्व में जिस प्रमुख साम्राज्य ने एक अखंड भारत की नींव रखी वह मौर्य साम्राज्य के नाम से जाना जाता है। इस वंश की स्थापना चंद्रगुप्त मौर्य के द्वारा की गयी थी परंतु इस वंश के एक प्रमुख शासक ने तत्कालीन देश की गतिविधि और विचारधारा को अप्रतिम रूप से परिवर्तित कर दिया, इतिहास में वह शासक ‘देवानंप्रिय अशोक’ के नाम से विख्यात हुआ। अशोक ने अपने शासन काल में अनेक लेख लिखवाए, यह लेख मुख्यतः उसके साम्राज्य के सीमाओं एवं प्रमुख नगरों में उत्कीर्ण थे। इन अभिलेखों से तत्कालीन मौर्य साम्राज्य के संपूर्ण परिदृश्य पर प्रकाश पड़ता है। इन अभिलेखों को सर्वप्रथम पढ़ने का श्रेय जेम्स प्रिंसेप को जाता है जिन्होंने 1837 में अशोक के शिलालेखों पर एक लेखमाला का प्रकाशन किया।अशोक के लेखों से अनेक महत्त्वपूर्ण जानकारियों पर प्रकाश पड़ता है जैसे- प्रशासनिक व्यवस्था, अशोक का धम्म, कलिंगयुद्ध, आर्थिक एवं धार्मिक जीवन। इन सभी महत्वपूर्ण तथ्यों के साथ तत्कालीन लोकजीवन पर भी समग्र दृष्टि प्राप्त होती है कि मौर्य काल में समाज में कौन सी प्रथाएँ प्रचलित थी, लोगों के सोचने का नज़रिया कैसा था, अशोक अपनी प्रजा से क्या अपेक्षाएँ रखता था एवं किस प्रकार के सामाजिक मूल्यों की अपेक्षा वह अपने समाज से कराता था। इस उद्देश्यसे प्रस्तुत शोध में अशोक के अभिलेखों विशेषकर वृहद् शिलालेखों में वर्णित लोकजीवन का किस प्रकार वर्णन मिलता है, का उल्लेख किया गया है।
The Distributed Multi Constrained Channel Access Mechanism By Using Framework For Mobile Adhoc Network
Authors: - U.Gomathi
Published: June 2024

The Mobile Ad hoc Network (MANET) is an autonomous wireless communication system, and does not have any fixed infrastructure. The Network loads which arise due to application evolving using MANET environment has to balance using routing protocol. Networks are increasingly resource intensive to efficiently manage the bandwidth & Energy in the group communication on basis of addressing the routing issues to provide the enhanced functionality of the network on basis of channel utilization and channel conditioning against load balancing.
In this research, proposed a novel unified framework for Distributed multi constrained Channel Access Mechanism for mobile Adhoc Network on inclusion of Scheduled Throughput Discriminant Multi-Data synchronization Strategies for Channel Allocation in Mobile Adhoc Network on various traffic patterns, Multi Trajectory Particle Swarm Optimization towards Optimal Velocity Control against load balancing and band width controlling and finally Self Adaptive Redundancy Elimination Clustering and Distributed Load Bandwidth Management Constraints for Mobile Ad Hoc Network.
Navigating the Digital Maze: Privacy and Security Challenges in the Era of Cloud Computing
Authors: - Harsh Pandey , - Chinmay Lunia , - Er. Nisha Rathore
Published: June 2024

In an era dominated by digital interactions, privacy and security have become paramount concerns across various sectors, ranging from personal communication to corporate data management. The research paper delves into the intricate relationship between privacy and security, exploring their symbiotic nature and the challenges faced in their harmonious integration. The study navigates through evolving technological landscapes, analyzing the implications of emerging technologies such as artificial intelligence, blockchain, and IoT on privacy and security frameworks. It investigates the ethical dimensions, legal implications, and user perceptions shaping the discourse around privacy and security. Furthermore, the paper examines innovative solutions, including
encryption techniques, biometric authentication, and privacy-preserving algorithms, designed to fortify digital ecosystems. Through comprehensive analysis and case studies, the research contributes valuable insights into the
delicate balance required to uphold individual privacy rights while ensuring robust security measures in an increasingly interconnected world. This exploration not only deepens our understanding of the privacy-security
paradigm but also provides practical recommendations for policymakers, businesses, and individuals striving to navigate the complex terrain of digital privacy and security
From Womb to Tooth : A Case Series
Authors: - Rimpy Mehra , - Tanvi Thakur , - Ashu Gupta , - Neha Sharma
Published: June 2024

The aim of this study was to evaluate the outcome of human amniotic membrane
as pulpotomy agent in permanent molars. Patients with diagnosis of irreversible pulpitis in mandibular molars of age group 18 to 49 years were selected and human amniotic membrane (hAM) was selected as pulpotomy agent as it is one of the biologically derived natural pulpotomy agent which may serve as better alternative for treating irreversible pulpitis. This case series consists of 4 patients treated with hAM as pulpotomy agents.
Flipped Classroom Approach and Acquisition of Problem Solving Skills in Mathematics in Secondary Schools in Turkana County
Authors: - Susan Awino Ouko
Published: June 2024

In a flipped classroom, learners study structured mathematics content prior to the lesson via watching relevant videos outside the lesson. This study initiated the use of flipped classroom approach in mathematics classrooms in order to strengthen learners’ problem- solving skills and impact performance. Reviewed literature shows a positive correlation between using flipped classroom approach and problem solving. The study design is quasi-experimental. One group of participants was instructed via flipped classroom approach and the other conventional methods. A comparison of problem-solving ability between the groups was made. The form two students and their mathematics teachers were the target population. Data was collected by means of an achievement test and means calculated per group. The inferential statistic, t-test was used to determine if the difference in means between the experimental and control group in the achievement test was significant. The study found that where flipped classroom approach is used, learners performed better in mathematics problem-solving than their counterparts instructed via conventional methods.
The Implementation of Selected Republic Act 9520 Provisions Among Multi-Purpose Cooperatives in the City of Mati
Authors: - Grace Jane N. Alcoser , - Janessa G. Pilar
Published: June 2024

This research study investigates the implementation of Republic Act 9520 (RA9520) provisions in Multi-Purpose Cooperatives, focusing on their purposes, objectives, and by-laws, while analyzing the demographic profile of cooperative members. Utilizing a descriptive-evaluative research design with a sample size of 385 active members, the study reveals a mature membership base, with a higher representation of females and a strong emphasis on longevity and commitment within cooperatives. The findings also indicated a very high level of implementation of the legislation, with By-Laws received the highest rating. Significant differences were observed in the implementation of cooperative purposes and objectives based on years of cooperative existence and membership. The study concluded that the MPCs in the City of Mati consistently adhere to RA9520, particularly emphasizing compliance with By-laws and objectives. However, variations in responses were noted when considering the demographic profiles of members.
Breast Cancer Detection using Machine Learning
Authors: - Samarth Kumar , - Simar Ahuja , - Shobha Rekh
Published: June 2024

Breast cancer is one of the worst cancer diseases in the world which affects a very large number of people. Detecting and diagnosing this disease early is vital, since it is crucial for the survival of the patient. The main objective of this study is to investigate the different technologies that are used for identifying and diagnosing breast cancers. Furthermore, it explores different machine learning approaches, computer-aided detection systems (CAD) and common medical treatments used to diagnose and treat these fatal diseases on a higher level. Also, there is a difference between commercial software and tools that are used for identifying and assessing all stages of breast cancer against tools and software that are provided by nonprofit organizations. The conclusion of this report is that there is no method or standardized procedure to identify and diagnose breast cancer using all technologies.