bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH KEPERCAYAAN DIRI SISWA DALAM MENCAPAI STANDAR KOMPETENSI LULUSAN SMK JURUSAN TATA NIAGA
Authors: Syabrus Hardisem
Published: December 2020

This research aims to determine the extent to which students have confidence in achieving graduate competency standards. The study was conducted by survey method using observation and questionnaires to 126 vocational students at the SMK Commerce in the City of Pekanbaru. The results of this research explained that in general, students’ self-confidence reached “graduated competency standard” at a moderate level (average = 3.57, STDV = .543). Which is there’s only 5 items from competency standards that have high self-confidence with percentage of 56,15%, while there’s 7 items that have moderate self-confidence with percentage of 43,85%. The results showed that the importance of growing students' confidence in achieving overall graduate competency standards, and it is expected that teachers also improve simulations in the learning process especially to improve 7 items in the competency standards so that high student confidence is achieved.
PUISI BERBASIS HASIL KARYA GAMBAR: UPAYA PENGUATAN LITERASI SISWA SD KELAS TINGGI
Authors: Setiawan Heri , Aji Styo Mahendra Wasita , Aziz Abdul
Published: December 2020

This study aims to examine and analyze the learning of writing poetry based on students' work drawings as an effort to strengthen the literacy of high grade elementary students. The method used is literature review by analyzing several studies related to the topic of discussion, namely literacy, drawing in elementary school, and poetry in the elementary school curriculum. From the results of the study produced a synthesis that shows that in primary school, literacy development still pivots on literacy reading. The ideas generated based on studies are developing fun writing literacy learning through writing "Poetry Based on Artwork" with the main steps: (1) determining the theme of the picture; (2) theme exploration; (3) drawing activities; (4) list beautiful words based on the drawings made (prewriting); (5) composing a framework of poetry (drafting); (6) developing poetry (writing); (7) editing and improving poetry (revising editing); and (8) reading the final poem arranged based on pictures (publishing). This activity is expected to strengthen the literacy of high class students with learning that combines drawing, poetry, writing, and communicating writing results holistically and pleasantly.
TUMPANG TINDIH PENGELOLAAN TEMPAT PARKIR (STUDI TENTANG RETRIBUSI DAN PAJAK PARKIR DI KOTA MALANG)
Authors: Larasati Dewi Citra , Rohman Abd.
Published: December 2020

Permasalahan parkir di Kota Malang sangatlah kompleks, terlebih ketika adanya kenaikan tarif parkir di tahun 2015, menyebabkan muncul masalah-masalah lain yang lebih pelik, seperti tumpang tindihnya pengelolaan pajak parkir dan retribusi, munculnya juru parkir ilegal sampai dengan premanisme. Latar belakang tersebut membuat peneliti melakukan penelitian dengan tujuan untuk menganalisis pengelolaan tempat parkir di Kota Malang. Peneliti menggunakan metode kualitatif dengan pendekatan yang holistik mampu menghasilkan data melalui teknik pengumpulan data menggunakan triangulasi. Dari kegiatan penelitian ini adalah adanya tumpang tindih pengelolaan tempat parkir antara pajak parkir dan retribusi parkir dikarenakan adanya dua perauran daerah yang mengatur keduanya dan belum ada perwal yang mengatur tentang pengelolaan parkir sehingga muncul konflik internal di Organisasi Perangkat Daerah (OPD) yang mengelola parkir maupun konflik eksternal (masyarakat), selain itu minimnya pengawasan dan pengendalian terhadap juru parkir ilegal yang ada di Kota Malang.The problem of parking in Malang is very complex, especially when there is an increase in parking fees in 2015. this causes other more complicated problems, such as overlapping management of parking taxes and user fees, the emergence of illegal parking attendants to thuggery. This background makes researchers conduct research with the aim to analyze the management of parking lots in the city of Malang.Researchers use qualitative methods with a holistic approach that is able to obtain data with data collection techniques using triangulation. The results of this research are the overlapping parking management between parking taxes and parking fees due to the absence of guardians governing parking management so that internal conflicts arise in the Regional Apparatus (OPD) that manages parking and external conflicts (the public), besides the lack of supervision and control Illegal parking attendant in Malang city
KINERJA BADAN KEPEGAWAIAN, PENDIDIKAN DAN PELATIHAN DAERAH KABUPATEN KOTABARU
Authors: Hermawan Ade , Bakhtiar H.
Published: December 2020

Tujuan penelitian ini untuk melihat kinerja Badan Kepegawaian, Pendidikan dan Pelatihan Daerah dengan merealisasikan visi dan misi Kabupaten Kotabaru. Metode yang digunakan dalam penelitian ini adalah metode evaluasi, yaitu suatu metode penelitian yang bertujuan melakukan penilaian terhadap kinerja Badan Kepegawaian, Pendidikan dan Pelatihan Kabupaten Kotabaru. Sumber data penelitian ini adalah sebagian Aparatur Sipil Negara yang pernah mendapatkan pelayanan dari Badan Kepegawaian, Pendidikan dan Pelatihan Kabupaten Kotabaru. Penelitian ini menggunakan analisa kualitatif yaitu mempelajari, menelaah dan menganalisa data, informasi dan fakta yang diperoleh kemudian data tersebut dibaca, dianalisa, dinterpretasikan dan diambil suatu kesimpulan. Hasil penelitian menunjukkan bahwa kinerja Badan Kepegawaian, Pendidikan dan Pelatihan Daerah Kabupaten Kotabaru dalam Penyelenggaraan pelayanan di Bidang Kepegawaian, Pendidikan dan Pelatihan kepada seluruh pegawai negeri sipil di lingkungan Pemerintah Kabupaten yang didasarkan pada indikator produktivitas, kualitas pelayanan dan akuntabilitas adalah dalam kategori Cukup baik. Kinerja Badan Kepegawaian, Pendidikan dan Pelatihan Daerah Kabupaten Kotabaru dalam Penyelenggaraan pelayanan di bidang kepegawaian, pendidikan dan pelatihan kepada seluruh pegawai negeri sipil di lingkungan Pemerintah Kabupaten Kotabaru dipengaruhi oleh faktor ketersediaan Sumber Daya Manusia (SDM) yang handal, sarana dan prasarana yang baik, anggaran yang proporsional dan memadai.

This study purpose is looking at the staffing agent performance, Education and Regional Training by realizing Kotabaru Regency’s vision and mission. The study method used is the evaluation method, which is a research method to evaluate Kotabaru Regency’s staffing agent performance, Education and Regional Training. This research data source is a part of the State Civil Apparatus who have received services from Kotabaru Regency’s staffing agent performance, Education and Regional Training. This research uses qualitative analysis which are learning, analyzing data, information and facts obtained then the data was read, analyzed, interpreted and decided a conclusion. The results showed that the staffing agent performance, Education and Regional Training in providing services in the staffing sector, Education and Training to all government employees in the Regency Government based on productivity indicators, service quality and accountability were in the Fairly good category. the staffing agent performance, Education and Regional Training in providing services in the staffing sector, Education and Training to all government employees in the Kotabaru Regency Government is influenced by the reliable Human Resources (HR)’s availability, good facilities and infrastructure, proportional and adequate budget.
Cost-effectiveness and budget impact of a lifestyle intervention to improve cardiometabolic health in patients with severe mental illness
Authors: Looijmans Anne , Jörg Frederike , Bruggeman Richard , Schoevers Robert A. , Corpeleijn Eva , Feenstra Talitha L , Van Asselt Antoinette D.I.
Published: December 2020

Methods: Patients (n = 244) were randomized to receive either care-as-usual or a lifestyle intervention in which mental health nurses coached patients in changing their lifestyle by using a web tool. Costs and quality of life were assessed at baseline and at 6 and 12 months. Incremental costs per centimeter waist circumference (WC) lost and per Quality-Adjusted Life Year (QALY) gained were assessed. Budget impact was estimated based on three intervention-uptake scenarios using a societal and a third-party payer perspective.
Results: Costs and reduction in WC were higher in the intervention (n = 114) than in the control (n = 94) group after 12 months, although not statistically significant, resulting in €1,370 per cm WC lost. QALYs did not differ between the groups, resulting in a low probability of the intervention being cost-effective in cost/QALY gained. The budget impact analysis showed that for a reasonable participation of 43%, total costs were around €81 million over 5 years, or on average €16 million annually (societal perspective).
Conclusions: The intervention is not cost-effective at 12 months and the budget impact over 5 years is substantial. Possibly, 12 months was too short to implement the intervention, improve cardiometabolic health, and reduce care costs. Therefore, the incentive for this intervention cannot be found in short-term financial advantages. However, there may be benefits associated with lifestyle interventions in the long term that remain unclear.
Cost-effectiveness of adding psychomotor therapy to a multidisciplinary rehabilitation program for chronic pain
Authors: Van der Maas Lia , Bosmans Judith E. , Van Tulder Maurits W. , Janssen Thomas W.J.
Published: December 2020

Introduction: This study assesses the cost-effectiveness (CE) of a multidisciplinary pain rehabilitation program (treatment as usual [TAU]) with and without psychomotor therapy (PMT) for chronic pain patients.

Methods: Chronic pain patients were assigned to TAU + PMT or TAU using cluster randomization. Clinical outcomes measured were health-related quality of life (HRQOL), pain-related disability, and quality-adjusted life years (QALYs). Costs were measured from a societal perspective. Multiple imputation was used for missing data. Uncertainty surrounding incremental CE ratios was estimated using bootstrapping and presented in CE planes and CE acceptability curves.

Results: Ninety-four chronic pain patients (n = 49 TAU + PMT and n = 45 TAU) were included. There were no significant differences in HRQOL, Pain Disability Index, and QALYs between TAU + PMT and TAU. Direct costs in TAU + PMT were significantly higher than in TAU (mean difference €3327, 95% confidence interval [CI] 1329; 5506). However, total societal costs in TAU + PMT were not significantly higher than in TAU (mean difference €642, 95% CI −3323; 4373). CE analyses showed that TAU + PMT was not cost-effective in comparison with TAU.

Conclusions: Adding PMT to a multidisciplinary pain rehabilitation program is not considered cost-effective in comparison with a multidisciplinary pain rehabilitation program alone. The results of this study should be interpreted with caution because of the small sample size and high drop-out rate.
Concepções sobre a Origem e Evolução da Vida por Licenciandos em Ciências da Natureza
Authors: Goulart Aline da Silva , Costa Márcio Tavares , Castro Luis Roberval Bortoluzzi , Pessano Edward Frederico Castro
Published: December 2020

O presente estudo, desenvolvido na Universidade Federal do Pampa – Campus Uruguaiana, buscou identificar e analisar as concepções prévias de estudantes ingressantes no Curso de Licenciatura em Ciências da Natureza sobre a temática da Origem e Evolução da Vida. A coleta de dados foi realizada por meio de questionário. Os resultados foram avaliados qualitativa e quantitativamente. Após a análise e discussão dos dados obtidos, conclui-se que a representação dos universitários ingressantes do Curso de Ciências da Natureza em relação à Origem e a Evolução da vida apresenta elementos que transitam entre a cultura religiosa e a abordagem científica. Houve respostas fragmentadas em relação ao eixo central da pergunta, ou inadequadas, mesclando teorias diversas. Ao expor este panorama, o trabalho contribui com o processo de formação dos discentes, e fornece dados ao corpo docente do curso a fim de promover estratégias pedagógicas direcionadas a melhoria dos processos de ensino.
Plantas medicinais e a extensão universitária: relato de experiência em tempos de COVID-19
Authors: Carvalho Morgana Maria Sousa Gadêlha de , Cordeiro Annyelle Anastácio , Melo Beatriz Simone Monteiro de , Dias Brenno Anderson Santiago , Sousa Flávia Regina Galvão de , Matias Juany de Souto , Figueiredo Lanna Lidia Monteiro , Deus Larissa Alves Assunção de , Amorim Luis Henrique Barbosa Alves , Silva Maria Isabel Araújo André da , Dias Maria Ismaela Lima de Barros , Silva Maria Luysa Almeida da , Rodrigues Matheus Andrade , Veríssimo Matheus Harllen Gonçalves , Silva Nathalia Fernandes da , Pereira Pauliny Anaiza de Almeida , Pereira Raquel Dantas , Lins Rodrigo Barros Esteves , Santos Vivian Luana Andrade dos , Freitas Yasmim Christynne Oliveira Reis de
Published: December 2020

Este artigo tem como finalidade relatar a experiência de discentes do curso de Odontologia em um projeto de extensão universitária, desenvolvido com professores da rede pública de ensino em conjunto com a Prefeitura Municipal e a Paróquia de Nossa Senhora da Conceição em Araruna-PB. O projeto tem o objetivo de capacitar os alunos a respeito da fitoterapia e sua relação com a odontologia, resgatando o uso de plantas medicinais e habilitando os futuros cirurgiões-dentistas para prescrever drogas vegetais. Trata-se de um estudo descritivo, do tipo relato de experiência, vivido por alunos do curso de Odontologia da Universidade Estadual da Paraíba (UEPB). A metodologia do projeto consiste em capacitar os estudantes por meio de minicursos, palestras, mesas redondas e atuação prática na comunidade local. Entretanto, diante do contexto da pandemia do novo Coronavírus, fez-se necessário adaptar as atividades de maneira remota através das ferramentas digitais como a plataforma Google Meet® e as redes sociais do projeto. Como resultados, houve a participação dos extensionistas em eventos científicos online, bem como a criação e divulgação de conteúdos informativos baseados em artigos científicos, propagando, dessa forma, maior conhecimento acerca da importância das plantas medicinais para a saúde. Diante disso, foi visto que, mesmo havendo mudanças no que diz respeito a execução do projeto, as atividades propostas foram realizadas com êxito, tendo como produto o aumento do conhecimento científico dos alunos e maior aproximação da comunidade com a temática abordada, comprovando a efetividade da extensão universitária em período de pandemia.
Desenvolvimento de abelhas melíferas em colmeias com diferentes cores e materiais de cobertura no semiárido brasileiro
Authors: Souza Maria de Fátima Pereira de , Santos Heidy Carvalho dos , Lima Yan Souza , Turco Silvia Helena Nogueira , Silva Eva Monica Sarmento da
Published: December 2020

O presente estudo teve o objetivo de verificar a influência de diferentes cores e materiais de cobertura em colmeias Langstroth analisando o desenvolvimento das abelhas melíferas (Apis mellifera). O experimento foi conduzido em um apiário experimental, em Petrolina (Pernambuco, Brasil).  Foram utilizadas 24 colmeias, dispostas em um delineamento inteiramente casualizado em esquema fatorial 3 x 2 (três cores e dois tipos de cobertura). O desenvolvimento das colônias foi analisado através de um mapeamento dos quadros de ninho e mensurações da temperatura interna das colmeias, em seguida, realizou-se a contagem de área contendo mel, pólen, crias de operária (fechadas e abertas) e crias de zangão. Os resultados indicam que em colmeias tradicionais (não pintadas) ou pintadas de branco, com e sem a placa de gesso sob sua tampa, há um maior armazenamento de pólen e mel, além da maior área com crias de abelhas operárias. Já em caixas Langstroth pintadas de azul, há um aumento da temperatura interna na colmeia, com uma maior área de crias de zangão. Dessa forma, manter as colmeias com cores claras e protegê-las com gesso é uma alternativa para evitar o aumento excessivo da temperatura interna nas colmeias.
A construção do lugar social da mulher no cordel: Uma análise do romance O mal em paga do bem, de Leandro Gomes de Barros
Authors: Neves Francisco Paiva das , Feitosa Adriana Madja dos Santos , Ribeiro Luís Távora Furtado , Oliveira Diana Nara da Silva
Published: December 2020

Este trabalho tem como objetivo refletir sobre a representação do lugar social da mulher na literatura popular, tendo como ponto de partida a análise do cordel O mal em paga do bem ou Rosa e Lino de Alencar, de autoria de Leandro Gomes de Barros. A pesquisa é bibliográfica e qualitativa, e investigou como o entorno social vivenciado pelo autor influenciou na construção dos personagens da narrativa. A representação da mulher no referido cordel é analisada à luz do contexto sócio-histórico do Brasil no período pré-industrial. Como suporte teórico da pesquisa, cabe dar destaque ao conceito de “mentalidade histórica de uma época”, desenvolvido por Lee Goff (2003), aos estudos sobre “a nova mulher”, de Hobsbawm (1988), e às reflexões de Pierre Bourdieu (2019) em torno do poder simbólico. Pode-se reconhecer que o poeta reproduz na personagem Rosa a concepção de mulher das sociedades pré-industriais, retratando-a no papel de dona de casa, mãe, educadora e, ao mesmo tempo, narrando formas incipientes de construções de emancipação feminina. Enfim, o poeta não cria, não idealiza, somente reproduz a imagem de mulher do seu tempo.
Distribuição e autocorrelação espacial dos casos de drogas ilícitas em um município do agreste nordestino
Authors: Medeiros Samara Costa da Nóbrega , Fook Sayonara Maria Lia , Olinda Ricardo Alves de
Published: December 2020

O artigo tem como objetivo verificar a distribuição e a autocorrelação espacial dos casos de indivíduos indiciados por porte de drogas ilícitas em um município do agreste nordestino. Trata-se de um estudo exploratório, quantitativo, transversal, baseado em documentos primários, a partir das dos laudos de Constatação pertinentes ao Instituto de Polícia Científica da Paraíba, entre os anos 2013 e 2017. Foram gerados mapas (Lisa e Moran) para a demonstração da distribuição espacial das notificações, além de diagramas, utilizando o Índice de Moran Global e o Índice Local de Moran, com auxílio do software estatístico gratuito The R Project for Statistical Computing (versão 3.4.2). Foi adotada como unidade de verificação a variável “Bairro de ocorrência” para nortear a análise espacial. Os bairros do Serrotão (n=143), José Pinheiro (n=102) e Bodocongó (n=77) constituíram os três bairros com maior número de casos registrados durante todo o período de estudo. Foram encontrados resultados estatísticos significativos para a autocorrelação espacial local entre os bairros periféricos do Serrotão, Bodocongó, Três Irmãs, Malvinas e José Pinheiro, mas em anos diferentes. Diante disso, o presente estudo permeou o norteamento do processo de tomada de decisão frente ao fenômeno das drogas, além de se constituir em uma ferramenta útil para guiar o planejamento de ações de combate ao consumo e comercialização ilegais na região do agreste nordestino.
Vulnerabilidades individuais, sociais e pragmáticas relacionadas às doenças endêmicas na Amazônia paraense
Authors: Lopes Andreza Cavalcante de Almeida , Silva Junior Ariamiro dos Santos , Araújo Carla Suellen Sousa , Anjos Dara Marcela Gama dos , Sousa Erika Fonseca de , Silva Jessica Clintiane Correa da , Lopes Lara Suellen Bezerra , Sousa Karina Alcântara de , Rocha Thâmera Jacqueline de Oliveira , Guimarães Thamires Pinheiro , Figueira Simone Aguiar da Silva , Valentim Livia de Aguiar , Luiz Olinda do Carmo
Published: December 2020

A vulnerabilidade se associa à suscetibilidade da população em relação a agravos e problemas de saúde e é pautada nas dimensões social, individual e pragmático. A localidade escolhida para realizar-se o estudo apresentou diversas fragilidades e relacionam-se diretamente a algumas doenças endêmicas da região. A pesquisa teve âmbito qualitativo, no qual foi utilizada uma abordagem analítica e descritiva numa comunidade da zona rural de Mojuí dos Campos, compreendendo três famílias residentes. As informações foram obtidas através de perguntas dos pesquisadores para os moradores. A família 01 compreende um casal de moradores que possuem alto grau de escolaridade, boas condições socioeconômicas e conhecimentos básicos a respeito das doenças endêmicas. A segunda família, composta por três pessoas com renda para atender apenas suas necessidades básicas, não possuem conhecimento básico sobre os sintomas de doenças endêmicas da região, apesar de já ter havido caso de dengue entre os integrantes. Já a família 03 possui precária condição de moradia e tem subsistência a partir da agricultura. Acredita-se que a qualidade dessas habitações tem resultado negativo na saúde da população. As três famílias não têm acesso a serviços de saúde, apesar de a segunda família afirmar que tem um ACS que visita sua casa. Percebeu-se que todos os moradores, mesmo aquele que tem renda familiar maior, estão expostos a algum tipo de vulnerabilidade, tanto pela própria situação geográfica nas quais essas famílias estão submetidas, quanto pelo acesso precário de serviços de saúde, coleta de lixo, água tratada.
Avaliação do consumo de substâncias psicotrópicas por estudantes da área da saúde: Retrato de uma década
Authors: Melo Antônia Pâmela Martins , Miranda Júnior Raimundo Nonato Cardoso
Published: December 2020

Nos últimos anos, os índices de consumo de drogas psicotrópicas na população brasileira têm-se elevado de forma exorbitante, caracterizando assim um fato preocupante para o país. Apesar da perspectiva terapêutica positiva que tais drogas trazem a população diante dos diversos problemas de saúde psicológica bem como os transtornos de ansiedade, seus resultados negativos também são dados relevantes que devem ser avaliados. Os psicotrópicos agem no sistema nervoso central, alterando padrões comportamentais, no entanto, é importante destacar que além dos efeitos colaterais provocados, o uso abusivo pode causar dependência química. Buscou-se nas bases de dados SciELO, ScienceDirect e Pubmed, artigos de revisão e originais, envolvendo o tema “estudantes universitários da área da saúde” atrelado a “consumo de psicotrópicos”. Foram considerados os artigos originais e trabalhos de revisão abordando o tema no período de 2007 a 2017, que apresentavam além de outras drogas, substâncias psicotrópicas, e desconsiderados aqueles que não abrangiam estudantes da área da saúde, e não tratavam de drogas psicotrópicas. Os dados foram agrupados estatisticamente e postos em tabelas. Foi possível observar que estudante do sexo masculino apresentaram mais suscetibilidade ao uso, é possível observar também que o consumo de álcool entre os estudantes é o item que apresenta maior percentual, visto que é uma droga lícita, facilmente incorporada nas mais diversas bebidas, além de ser socialmente aceito. É possível concluir que o estresse gerado pela rotina acadêmica atrelado a fatores sociais, podem levar o estudante a ter contato mais facilmente com estas substâncias.
Excessive Daytime Sleepiness in Sleep Apnea: Any Role of Testosterone or Vitamin D?
Authors: ŠIARNIK P , JURÍK M , HARDOŇOVÁ M , KLOBUČNÍKOVÁ K , VEVERKA J , ŠURDA P , TURČÁNI P , KOLLÁR B
Published: December 2020

Recent studies reported association of sleep-disordered breathing (SDB) with testosterone and vitamin D deficiency. Low testosterone and vitamin D levels have been linked to fatigue and excessive daytime sleepiness (EDS). However, the impact of testosterone and vitamin D deficiency on EDS in subjects with SDB remains unknown. The aim of this study was to explore the predictors of EDS in habitual snorers. Role of testosterone, and vitamin D was studied in detail. We also looked for associations between testosterone, vitamin D, and sleep-related indices. We prospectively enrolled 291 consecutive male patients with habitual snoring. Baseline clinical characteristics were recorded on admission. Standard overnight polysomnography was performed to detect SDB, and Epworth Sleepiness Scale (ESS) was used to assess EDS. Blood samples were obtained in a fasting condition in the morning after polysomnography to determine levels of testosterone and vitamin D. Respiratory disturbance index (RDI) (95 % CI: 1.004-1.024, p=0.005) and the use of antihistamines (95 % CI: 1.083-11.901, p=0.037) were the only independent variables significantly associated with EDS in binary logistic regression analysis. In linear multiple regression analysis, body mass index (BMI) (Beta=-0.282, p˂0.001) and oxygen desaturation index (Beta=-0.150, p=0.043) were the only independent variables significantly associated with testosterone levels, and BMI (Beta=-0.142, p=0.016) was the only independent variable significantly associated with vitamin D. We failed to find any independent association of testosterone and vitamin D with subjectively rated EDS among habitual snorers. Our results suggest an independent association between the magnitude of nocturnal desaturation and testosterone levels.
Design and Analysis of Warning System for Aircraft Wingtip Proximity to Hangar Column using Ultrasonic Sensor
Authors: Sutiawan Sutiawan , Hendriana Dena , Berchmans Hanny J , Nasution Henry , Baskoro Gembong
Published: December 2020

Aircraft maintenance is using very large hangar as a place to work on the aircrafts and the hangar can fit several aircrafts at the same time. The aircrafts are moved using tow cars in and out of the hangar. The hangar is so big that it requires columns for its structure and these columns present risk to the aircrafts for having wingtip collitions during towing in and out of the hangar. In this study, warning system for aircraft wingtip proximity to the hangar columns is designed. This warning system is using ultrasonic sensors attached to the columns and controlled by Arduino micro processor and wirelessly connected as Internet of Things system to warn the driver of the tow car. The ultrasonic sensors are placed in the columns based on dimension and elevation of 2 different most common aircraft wingtips to get effective column warning system. The speed of tow car affects the driver time to response the warning and based on calculations and experiments, the tow car driver should have enough time to respond the warning system.
Comparative Analysis of the Legal Status of an Expert in Civil and Arbitration Proceedings
Authors: Khegai
Published: December 2020

This article is devoted to the problematic aspects of the legal status of experts in arbitration and civil proceedings. The object of this article is the social relations arising in connection with the appointment and production of expertise in civil and arbitration proceedings. The role and significance of an expert in civil and arbitration proceedings are determined, and the features of the legal status of an expert in civil and arbitration proceedings are highlighted through a comparative analysis. The differences in the legal status of experts are revealed, which can negatively affect the effectiveness of forensic examination and the process of proving in general.
Legal Policy of the Kyrgyz Republic on Digitalization of Social Security: Problems and Prospects
Authors: Kachkyn kyzy G.
Published: December 2020

The article discusses the prerequisites and conditions for the development of digital technologies in the legal policy of the Kyrgyz Republic, the mechanism of their influence on the acceleration of processes in the social sphere: simplification of the issuance of state benefits, ensuring the protection and registration of children and families in difficult life situations, digitalization of the system for promoting employment of the population, improving the quality of service for pension recipients and what problems, risks and challenges arise in this regard. The most important results of the digitalization of the social security sphere are the creation of prerequisites for the growth of the cultural and legal level of the population due to the rapid development of the digital environment. The author comes to the conclusion that by developing digitalization in the field of socially significant services, the state should be responsible for the reliability and correctness of information translated into electronic format, in turn, the population needs a transition to lifelong learning, to lifelong education and retraining of personnel.
Constitutional Provisions and Topical Issues of Determining the Legal Status of Voluntary Associations of Citizens Pursuing Law Enforcement Goals in the Kyrgyz Republic
Authors: Djumagulov A. , Turapova B.
Published: December 2020

The article deals with topical issues of determining the legal status of voluntary associations of citizens for protection of law and order in Kyrgyzstan in the context of the constitutional right to security of person.
Kosova Toplumunda Covid-19 Korkusu, Anksiyete ve Bireysel Dindarlık Üzerine Bir Araştırma
Authors: Gashi Feim
Published: December 2020

Covid-19 Dünya Sağlık Örgütü (WHO/DSÖ) tarafından son dönemlerde yaşanmış en ciddi virüslerden biri olarak kabul edilmektedir. Zira Dünya Sağlık Örgütü covid-19’u Mart ayından itibaren pandemi olarak ilan etti. Bu ilan, covid-19 virüsünün dünyanın çoğu bölgesinde yayıldığını göstermektedir. Virüsün hızlı yayılışı ve ölüm oranlarının yüksek olması insanlarda korku, kaygı, anksiyete vb. psikolojik durumların artmasına neden olmuştur. Bu gerçeklerden yola çıkarak Kosova’da yaşayan insanların covid-19 gerçeğinin karşısında korku, anksiyete ve bireysel dindarlık durumlarını tespit etmeye çalıştık. Ayrıca covid-19’un sağlamış olduğu korku ile bireysel dindarlık, yaş, cinsiyet, eğitim ve ekonomik durum arasındaki ilişkiyi tespit etmeye çalıştık. Araştırma, tarama yöntemine uygun, anket tekniğinin kullanıldığı bir saha araştırması niteliğindedir. Örneklem, Kosova’da yaşayan bireylerden (N=152) oluşmaktadır. Örnekleme, “Covid-19 Korkusu”, “Yaygın Anksiyete Bozukluğu” ve “Bireysel Din Envanteri” uygulanmıştır. Elde edilen bulgulara göre, bireysel dindarlık ile covid-19 ve eğitim durumu; anksiyete ile cinsiyet ve ekonomik durum arasında anlamlı bir farklılık görülmüştür. Bunun yanında covid-19 korkusu ve anksiyete değişkenleri arasında pozitif; covid-19 korkusu ve beş vakit namaz kılma ile Ramazan orucu tutma arasında negatif yönlü bir korelasyonun olduğu tespit edilmiştir.
Clinical Profile and Approach to Osteal LAD Lesion During Primary Angioplasty in Myocardial Infarction (PAMI)
Authors: Sanzgiri Prakash , Reddy KV Charan , Thanedar Rohan , Kudva Srinivas
Published: December 2020

Isolated Coronary Artery Stenoses (CAS) involving the ostium of the Left Anterior Descending (LAD) artery is very challenging, especially in a setting of primary Angioplasty in Myocardial Infarction (PAMI). Intimal atherosclerosis in the Left Main Coronary Artery (LMCA) bifurcation is primarily in area of low shear stress which is the lateral wall, close to the LAD and Left Circumflex (LCx). Thus, carina is usually free of disease, which can explain why single-stent strategy can be successful. However, precise stent placement is often difficult due to unwanted stent movement within vessel or its proximity to side branches. A decision must be made at the outset, to decide on the approach to be employed, to treat osteal LAD lesions. Limited data is available on patients undergoing primary PCI of osteal LAD lesions. Here, we present our experience and problems encountered during the management of osteal LAD lesions in the setting of PAMI.
"Evde Kalmış Bir Kız" Olmanın Trajedisi: Tarık Buğra Hikâyesi Üzerine Bir Okuma
Authors: Tek Zeynep
Published: December 2020

Tarık Buğra’nın (1918-1994) gündelik hayatın kesitlerinden oluşan hikâyelerinde sıradan insan yaşamlarının çeşitli yönlerine tanık olunur. Bu tür metinlerden biri de insan varoluşunda anlam ve amacın kaybıyla şekillenen bir yaşam hikâyesini ele alan “Var Olmak Veya Olmamak”tır (1953). Hikâyede otuz dört yaşında çirkin, evde kalmış bir kız olarak tarif edilen ve erken Cumhuriyet dönemine (1923-1950) tanıklık ettiği anlaşılan bir öğretmenin intiharla sonuçlanan trajedisine yer verilir. Müntehir öğretmenin yeğeni tarafından anlatılan hikâye, onun bir gemideki son anlarına ve geçmişteki kırılma noktalarına odaklanır. Bu anlatım üzerinden, gün geçtikçe artan yalnızlığın kendisinde çirkinlik düşüncesini tetiklediği ve bunun sonucunda ortaya çıkan aşağılık kompleksinin yaşama sevincine ve uyum becerisine telafisi olmayacak şekilde zarar verdiği anlaşılır. Mevcut çalışma, söz konusu trajedinin temelindeki çatışmayı, öğretmenin son anlarına ve evde kalmanın erken Cumhuriyet dönemindeki anlamına odaklanarak irdelemeyi amaçlar. Bekârlık, çirkinlik ve ölümün yan yana geldiği anlatıda kendi olmanın gücünden mahrum kalan hikâye kişisinin var olamamasına yol açan psiko-sosyal bağlamı inceler. Buna bağlı olarak geleneksel yaşam biçimi ile Cumhuriyet dönemi modernleşmesinin örtüşen normlarının kadın öğretmen üzerinde ağır kamusal beklentilere ve travmatik etkilere yol açtığı sonucuna varılır. Öğretmenin kamusal alanda güçlü bir kadın karakter olarak ataerkil baskılara maruz kalışı, toplumun bağımsız kadın figürlerine aşina olmamasıyla ilgili olabilir. Kadının evlenmemesi durumunda kusurlu olduğu düşüncesine kapılması da toplumun (ön) yargılarını kolektif öznelliğin bir üyesi olarak içselleştirmenin sonucu olarak değerlendirebilir. Yeni kamusal alanların inşasında rol alan Cumhuriyet kızlarının içsel güç kaybı, yerleşik toplumsal algıları dönüştürmenin ve bununla edilecek mücadelenin zorluğuna işaret eder.
Current Challenges and Opportunities in Non-native Chemical Production by Engineered Yeasts
Authors: Kim Jiwon , Hoang Nguyen Tran Phuong , Lee Sun-Mi
Published: December 2020

Yeasts are promising industrial hosts for sustainable production of fuels and chemicals. Apart from efficient bioethanol production, yeasts have recently demonstrated their potential for biodiesel production from renewable resources. The fuel-oriented product profiles of yeasts are now expanding to include non-native chemicals with the advances in synthetic biology. In this review, current challenges and opportunities in yeast engineering for sustainable production of non-native chemicals will be discussed, with a focus on the comparative evaluation of a bioethanol-producing Saccharomyces cerevisiae strain and a biodiesel-producing Yarrowia lipolytica strain. Synthetic pathways diverging from the distinctive cellular metabolism of these yeasts guide future directions for product-specific engineering strategies for the sustainable production of non-native chemicals on an industrial scale.
What Can Cellular Redox, Iron, and Reactive Oxygen Species Suggest About the Mechanisms and Potential Therapy of COVID-19?
Authors: Muhoberac Barry B.
Published: December 2020

Accumulating evidence suggests that there are important contributions to coronavirus disease (COVID-19) from redox imbalance and improperly coordinated iron, which cause cellular oxidative damage and stress. Cells have developed elaborate redox-dependent processes to handle and store iron, and their disfunction leads to several serious diseases. Cellular reductants are important as reactive oxygen species (ROS) scavengers and to power enzymatic repair mechanisms, but they also may help generate toxic ROS. These complicated interrelationships are presented in terms of a cellular redox/iron/ROS triad, including ROS generation both at improperly coordinated iron and enzymatically, ROS interconvertibility, cellular signaling and damage, and reductant and iron chelator concentration-dependent effects. This perspective provides the rational necessary to strongly suggest that COVID-19 disrupts this interdependent triad, producing a substantial contribution to the ROS load, which causes direct ROS-induced protein and phospholipid damage, taxes cellular resources and repair mechanisms, and alters cellular signaling, especially in the more critical acute respiratory distress syndrome (ARDS) phase of the infection. Specific suggestions for therapeutic interventions using reductants and chelators that may help treat COVID-19 are discussed.
Signaling Functions of Intramembrane Aspartyl-Proteases
Authors: Papadopoulou Alkmini A. , Fluhrer Regina
Published: December 2020

Intramembrane proteolysis is more than a mechanism to “clean” the membranes from proteins no longer needed. By non-reversibly modifying transmembrane proteins, intramembrane cleaving proteases hold key roles in multiple signaling pathways and often distinguish physiological from pathological conditions. Signal peptide peptidase (SPP) and signal peptide peptidase-like proteases (SPPLs) recently have been associated with multiple functions in the field of signal transduction. SPP/SPPLs together with presenilins (PSs) are the only two families of intramembrane cleaving aspartyl proteases known in mammals. PS1 or PS2 comprise the catalytic center of the γ-secretase complex, which is well-studied in the context of Alzheimer's disease. The mammalian SPP/SPPL family of intramembrane cleaving proteases consists of five members: SPP and its homologous proteins SPPL2a, SPPL2b, SPPL2c, and SPPL3. Although these proteases were discovered due to their homology to PSs, it became evident in the past two decades that no physiological functions are shared between these two families. Based on studies in cell culture models various substrates of SPP/SPPL proteases have been identified in the past years and recently-developed mouse lines lacking individual members of this protease family, will help to further clarify the physiological functions of these proteases. In this review we concentrate on signaling roles of mammalian intramembrane cleaving aspartyl proteases. In particular, we will highlight the signaling roles of PS via its substrates NOTCH, VEGF, and others, mainly focusing on its involvement in vasculature. Delineating also signaling pathways that are affected and/or controlled by SPP/SPPL proteases. From SPP's participation in tumor progression and survival, to SPPL3's regulation of protein glycosylation and SPPL2c's control over cellular calcium stores, various crossovers between proteolytic activity of intramembrane proteases and cell signaling will be described.
Antioxidant Therapy in Graves’ Orbitopathy
Authors: Lanzolla Giulia , Marcocci Claudio , Marinò Michele
Published: December 2020

The balance of the cell redox state is a key point for the maintenance of cellular homeostasis. Increased reactive oxygen species (ROS) generation leads to oxidative damage of tissues, which is involved in the development of several diseases, including autoimmune diseases. Graves’ Orbitopathy (GO) is a disfiguring autoimmune-related condition associated with Graves’ Disease (GD). Patients with active, moderate-to-severe GO, are generally treated with high doses intravenous glucocorticoids (ivGCs) and/or orbital radiotherapy. On the contrary, up to recently, local ointments were the treatment most frequently offered to patients with mild GO, because the risks related to ivGCs does not justify the relatively poor benefits expected in mild GO. However, a medical treatment for these patients is heavily wanted, considering that GO can progress into more severe forms and also patients with mild GO complain with an impairment in their quality of life. Thus, based on the role of oxidative stress in the pathogenesis of GO, a therapy with antioxidant agents has been proposed and a number of studies have been performed, both in vitro and in vivo, which is reviewed here.
Incorporating Established Conservation Networks into Freshwater Conservation Planning Results in More Workable Prioritizations
Authors: Sievert Nicholas A. , Paukert Craig P. , Whittier Joanna B.
Published: December 2020

Resources for addressing stream fish conservation issues are often limited and the stressors impacting fish continue to increase, so decision makers often rely on tools to prioritize locations for conservation actions. Because conservation networks already exist in many areas, incorporating these into the planning process can increase the ability of decision makers to carry out management actions. In this study we aim to identify priority areas within established networks to provide an approach which allows managers to focus efforts on the most valuable areas they control, while identifying areas outside of the network, which support species with minimal representation within the network, for acquisition or conservation partnerships. The goal of this approach is to prioritize sites to achieve high levels of species representation while also developing workable solutions. We applied a methodology incorporating established networks into a systematic conservation planning process for fish in temperate wadeable streams located in Missouri, USA. We compared how well species were represented in our approach with two commonly used alternatives: A blank slate approach which used the same systematic conservation planning technique but did not incorporate established networks, and a habitat integrity approach based solely on anthropogenic threat data. Relative to the blank slate approach, our approach required 210% more segments for representation of all species, and contained an average of 0.5 additional occurrences for the least well-represented species. Although the blank slate solution was more efficient in achieving species representation, 77% of segments in this solution were not already protected. This would likely pose a challenge for implementing conservation actions. Relative to habitat integrity-based priorities, our approach required only 38% of the number of stream segments to achieve representation of all species and contained an average of 5 additional occurrences of the least represented species, representing a substantial gain in representation. Incorporating established networks may allow managers to focus resources on areas with the greatest conservation value within established networks and to identify the most valuable areas complementary to the established networks, resulting in priorities which may be more actionable and effective than those developed by alternative approaches.
Consequences of Replacing Native Savannahs With Acacia Plantations for the Taxonomic, Functional, and Phylogenetic α- and β-Diversity of Bats in the Northern Brazilian Amazon
Authors: Carvalho William Douglas , Meyer Christoph F. J. , Xavier Bruna da Silva , Mustin Karen , Castro Isaí Jorge de , Silvestre Saulo M. , Pathek Dinah B. , Capaverde Ubirajara D. , Hilário Renato , Toledo José Júlio de
Published: December 2020

Across the globe, millions of hectares of native vegetation have been replaced by commercial plantations, with negative consequences for biodiversity. The effects of the replacement of native vegetation with commercial plantations on the functional and phylogenetic diversity of bat assemblages remain understudied, and most studies have focused exclusively on the taxonomic component of diversity. Here, we investigate how the replacement of natural savannahs by acacia plantations affects the α- and β-diversity of bat assemblages. We sampled bats, using mist-nets at ground level, in natural forest, savannah areas and acacia plantations, in the Lavrados de Roraima in the northern Brazilian Amazon. Our results show that, in general, acacia is less diverse than native forests in terms of taxonomic and functional diversity, and is also less taxonomically diverse than the savannah matrix which it substitutes. The observed patterns of α- and β-diversity found in the present study are in large part driven by the superabundance of one generalist and opportunistic species,Carollia perspicillata, in the acacia plantations. Taken together, our results show that the replacement of areas of natural savannah by acacia plantations causes a regional loss in diversity across all diversity dimensions: taxonomic, functional and phylogenetic. However, further studies are required to fully understand the ecological and conservation implications of this landscape change.
Analysis of Hub Genes Involved in Distinction Between Aged and Fetal Bone Marrow Mesenchymal Stem Cells by Robust Rank Aggregation and Multiple Functional Annotation Methods
Authors: Liu Xiaoyao , Yin Mingjing , Liu Xinpeng , Da Junlong , Zhang Kai , Zhang Xinjian , Liu Lixue , Wang Jianqun , Jin Han , Liu Zhongshuang , Zhang Bin , Li Ying
Published: December 2020

Stem cells from fetal tissue protect against aging and possess greater proliferative capacity than their adult counterparts. These cells can more readily expand in vitro and senesce later in culture. However, the underlying molecular mechanisms for these differences are still not fully understood. In this study, we used a robust rank aggregation (RRA) method to discover robust differentially expressed genes (DEGs) between fetal bone marrow mesenchymal stem cells (fMSCs) and aged adult bone marrow mesenchymal stem cells (aMSCs). Multiple methods, including gene set enrichment analysis (GSEA), Gene Ontology (GO) analysis, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis were performed for functional annotation of the robust DEGs, and the results were visualized using the R software. The hub genes and other genes with which they interacted directly were detected by protein–protein interaction (PPI) network analysis. Correlation of gene expression was measured by Pearson correlation coefficient. A total of 388 up-regulated and 289 down-regulated DEGs were identified between aMSCs and fMSCs. We found that the down-regulated genes were mainly involved in the cell cycle, telomerase activity, and stem cell proliferation. The up-regulated DEGs were associated with cell adhesion molecules, extracellular matrix (ECM)–receptor interactions, and the immune response. We screened out four hub genes, MYC, KIF20A, HLA-DRA, and HLA-DPA1, through PPI-network analysis. The MYC gene was negatively correlated with TXNIP, an age-related gene, and KIF20A was extensively involved in the cell cycle. The results suggested that MSCs derived from the bone marrow of an elderly donor present a pro-inflammatory phenotype compared with that of fMSCs, and the HLA-DRA and HLA-DPA1 genes are related to the immune response. These findings provide new insights into the differences between aMSCs and fMSCs and may suggest novel strategies for ex vivo expansion and application of adult MSCs.
Identification of Allelic Variation in Drought Responsive Dehydrin Gene Based on Sequence Similarity in Chickpea (Cicer arietinum L.)
Authors: Kumar Tapan , Tiwari Neha , Bharadwaj Chellapilla , Sarker Ashutosh , Pappula Sneha Priya Reddy , Singh Sarvjeet , Singh Mohar
Published: December 2020

Chickpea (Cicer arietinumL.) is an economically important food legume grown in arid and semi-arid regions of the world. Chickpea is cultivated mainly in the rainfed, residual moisture, and restricted irrigation condition. The crop is always prone to drought stress which is resulting in flower drop, unfilled pods, and is a major yield reducer in many parts of the world. The present study elucidates the association between candidate gene and morpho-physiological traits for the screening of drought tolerance in chickpea. Abiotic stress-responsive gene Dehydrin (DHN) was identified in some of the chickpea genotypes based on the sequence similarity approach to play a major role in drought tolerance. Analysis of variance revealed a significant effect of drought on relative water content, membrane stability index, plant height, and yield traits. The genotypes Pusa1103, Pusa362, and ICC4958 were found most promising genotypes for drought tolerance as they maintained the higher value of osmotic regulations and yield characters. The results were further supported by a sequence similarity approach for the dehydrin gene when analyzed for the presence of single nucleotide polymorphisms (SNPs) and indels. Homozygous indels and single nucleotide polymorphisms were found after the sequencing in some of the selected genotypes.