bluuebunny/crossref_metadata_2025 huggingface dataset:
Penerapan Alat Pembuatan Kotak Kardus Yang Ergonomis Berdasarkan Ukuran Anthropometri
Authors: Mujiono  , Sujianto  , Hardianto  , Alifia Yesi,Frista Yessita,Devva,SitiAisyah,Ina Anggraini
Published: October 2020

Tim abdimas melakukan pertemuan untuk membahas pelaksanaan yang akan dilakukan untuk melakukan survey kelokasi mitra yang akan dijadikan obyek untuk abdimas. Tujuan dari survey ini untuk mengetahui apa saja yang dibutuhkan oleh mitra, hasilnya informasi yang diperoleh dari mitra adalah sering terjadinya kecelakaan, rusak, ukuran tidak bisa sama dalam melakukan pembuatan kotak kardus karena  alat yang dipergunakan masih sangat sederhana yaitu cutter, pisau potong tekan atau pisau silet, mal kotak kardus dan mal kotak kardus dibedakan jadi dua sisi, sisi kanan dan sisi kiri kemudian kedua sisi tersebut  dilem pakai lem kayu.

                Melihat kondisi yang terjadi pada mitra tersebut maka tim abdimas akan mengembangkan/inovasi perancangan alat pembuatan kotak kardos dengan menggunakan alat dengan desain ergonomis. Desain ergonomis yang dimaksud adalah desain alat yang menghasilkan suatu sistem kerja dengan menggunakan ukuran anthropometri., dengan tujuan agar supaya mitra lebih mudah untuk mengunakan alat tersebut dan  menghidari sering terjadinya kecelakaan, kerusakan,  sehingga pekerjaan mitra lebih effektif,effisien dapat menghemat waktu sehingga hasil jauh lebih baik dan produktif.

Melihat masalah yang dihadapi mitra maka tim abdimas membuatkan alat dengan menggunakan data anthropometri dengan ukuran alat tinggi 105 cm, lebar 77 cm dan panjang 85 cm, sehingga dapat meningkatan produktifitas dari 2.4 kodi per jam menjadi 9.6 kodi per jam.
Real Time Wireless PPG & Respiration Rate Measurement and Data Acquisition System
Authors: Das Dipon , Pradhan Swarna Kamal
Published: October 2020

RWPRRDAS is a wireless
Photoplethysmography (PPG) and respiration measurement system which allows user
to monitor the measured heart rate, blood pressure wave, respiration cycle and
any other kind abnormality related to heart and its corresponding system. It
uses a battery powered transducer to collect biomedical data and an android
application to visualize the data in a proper manner and in a graphical way.
This is a non-invasive type measurement procedure. This is a truly a mobile
system which is easy to carry and operate. Since this device is not connected
to power lines of AC applications and totally battery operated so there is no
possibility of any electrical hazard in any case.

 Nowadays, many biomedical transducers come with a
custom-made processor with an inbuild display, which offers very low processing
power to visualize the biomedical data properly and with an ease of access to
almost every age. RWPRRDAS collects the data using transducer and uses the
processing power of a modern android mobile phone so that visualization and
determination of heart disease and abnormality in respiration mechanisms become
easy and reliable. And the measurement of data through a wireless media
provides hassle-free & user friendly usable limit to almost every person.
Integrando Universidade e Escola: Relato de experiência da Oficina “Brincando de Geneticista: descobrindo o DNA”
Authors: Santos Rogério Mercês Ferreira , Santiago Mattheus Luís Alves , Benevides Raquel Guimarães , Oliveira Simone Souza de , Ribeiro Lara Oliveira L. , Granjeiro Érica Maria
Published: October 2020

Objetivo: relatar uma experiência didática envolvendo diálogo entre a Universidade e a Escola Pública, por meio da aplicação da oficina pedagógica denominada “Brincando de Geneticista: descobrindo o DNA”. Método: A oficina direcionada para alunos da Educação Básica foi realizada na Universidade Estadual de Feira de Santana, durante a Semana Nacional de Ciência e Tecnologia do ano de 2019. A atividade pedagógica foi fundamentada na extração de material genético. Foram utilizados materiais de baixo custo e fácil acesso. Resultados: 80 estudantes Ensino Fundamental II participaram da oficina. Os alunos foram divididos em pequenos grupos, possibilitando maior interação entre estudantes e professor. A oficina de caráter participativo possibilitou que os estudantes pudessem compreender a importância da genética para a vida, além de estimular a interação dos escolares com a Universidade. Ademais, foi observado que muitos escolares apresentam dificuldades para transpor e contextualizar assuntos relacionados a conteúdos celulares e moleculares. Conclusão: No presente trabalho, o uso dessa abordagem didática ampliou a receptividade dos alunos aos conteúdos trabalhados, facilitou o diálogo aluno-professor e se mostrou uma ótima ferramenta de interface entre universidade e escola básica.
Dispossessing Detroit: How the Law Takes Property
Authors: Sickel Mary
Published: October 2020

Introduction for the University of Michigan Journal of Law Reform's Symposium “Dispossessing Detroit: How the Law Takes Property,” hosted on November 9 and 10, 2019.
The Concept Maslahah of Najamuddin al Tufi and It's Relevance of Sharia Business
Authors: Munadi Munadi , Iswanto Budi
Published: October 2020

Al-Tufi is one of the maslahah figures. al-Al-Tufi defines maslahah based on two things, in urf and shar'i, while in urf is a factor that leads to goodness and benefits. Like trading that brings profit. While according to shar'i maslahah is a causal factor that leads to the intention of lawmakers in matters of worship, as well as customs. The rationalization effort based on the spirit of shar'i arguments in its dialectical form delivered Al-Tufi's thoughts towards the re-actualization of Islamic law in the field of muamalah which was more applicable and found a significant momentum. Considering the need for renewal of Islamic law based on public benefit is more pronounced in this modern era especially in business, with this Al-Tufi method, Sharia business law will be dynamic and progressive again. Is not the Islamic Sharia down to earth with the aim of achieving human maslahah.
Comercio de lanas, estructura agraria y oligaría en el sur del Perú
Authors: Jacobsen Nils
Published: October 2020

El desarrollo económico en el sur del Perú hacia fines del siglo XIX y comienzos del siglo XX, un periodo en que la exportación de la lana fue de importancia determinante, representa un problema especial para la historia peruana: ¿Por qué? -en las haciendas ganaderas y las comunidades indígenas- se mantuvieron tan tradicionales y arcaicas las estructuras de la producción agraria, sin que se produjeran inversiones de capitales, se intensificara los métodos de producción o se introdujeran relaciones de trabajo asalariado en las grandes propiedades agrícolas?
Tendencias estructurales del campesinado en el Perú
Authors: Jurado Joel
Published: October 2020

Today there is a tendency to question the political validity of the popular social classes, as it is argued that new actors have entered the social scene displacing them from the expected role in the transformation of our societies. Thus, in Peru it is repeatedly argued that the social agents that are causing the greatest changes are no longer precisely the conventional popular classes, but rather social sectors such as the urban poor, state workers, women, youth, migrants, regional movements, among others.
Presión colonial y reivindicación indígena en Cajamarca (1785-1820) según el archivo del "Protector de naturales"
Authors: Lavalle Bernard
Published: October 2020

De unos quince años a esta parte, el recurso cada vez más frecuente a los archivos locales es una de las características dominantes de las nuevas orientaciones de la historiografía peruana sobre la época colonial. Así, se fueron renovando, vivificando y matizando los análisis hasta entonces fundamentados y estructurados esencialmente a partir de repositorios conservados en Lima o Sevilla. Curiosamente, en tal contexto, Cajamarca que fuera en la época española la cabecera de un corregimiento a la vez amplio, poblado y activo —de hecho la verdadera capital de los Andes del norte a pesar de la decisión colonial de establecer en la costa, en Trujillo, la sede del obispado— no parece haber suscitado las investigaciones que obviamente se merece y son posibles dada la riqueza de su archivo departamental notablemente clasificado y bien conservado.
La cosecha de maíz en Yucay
Authors: Mayta Medina Faustino
Published: October 2020

La presentación de este trabajo no supone una hipótesis que requiera de un planteamiento doctrinario, científicamente imprescindible. La recopilación del material de campo se debe a la necesidad de satisfacer la pregunta "¿Cómo funcionan los ritos tradicionales, mágicos-religiosos, en las labores agrícolas y cuáles son las consecuencias socio-culturales en el proceso de cambios que se operan en el valle sagrado de los incas?" Los trabajadores y algunos alumnos de la Granja de Yucay fueron los informantes para la presente recopilación de datos, que a nuestro parecer, reflejan la realidad sin distorsionarla.
Osteoclast biology in bone resorption: a review
Authors: Fu Chao , Shi Ruyi
Published: October 2020

What we know about bone resorption has changed a lot in the last few decades. The osteoclast is the only cell to nibble and break down the bone, and in the formation and resorption of bone tissue, osteoclasts play an important role. Once the balance of bone formation and bone loss is out of control, diseases like osteopetrosis and osteoporosis occur. Bone resorption is a unique function of osteoblasts, which are multinucleated cells formed by the fusion of mononuclear progenitor cells of the monocyte/macrophage family. In the formation of osteoclasts, there are two main factors affecting this process, macrophage colony-stimulating factor (M-CSF) and ligand-activated receptor (RANKL) of nuclear factor kappa B (NF-κB). The identification of RANK-RANKL signaling and other classic signaling pathways such as Wnt and Notch, as the major signaling regulation in osteoclast differentiation, was a significant breakthrough in the field of osteoclastogenesis. In this review, we briefly describe the latest knowledge of osteoclast-induced bone resorption and cellular factors that regulate the activity of osteoclasts and cell fusion, for the purpose of understanding osteoclastogenesis and the development of drugs that enhance bone resorption to improve pathological bone diseases.
PENGEMBANGAN MODUL BERBASIS RME UNTUK MENINGKATKAN KEMAMPUAN LITERASI MATEMATIKA SISWA KELAS XI SMK
Authors: Putri Dina Agustin , Susanti Vera Dewi , Apriandi Davi
Published: October 2020

This development research aims to analyze the level of validity, effectiveness, and practicality of the RME-based learning modules as well as how the modules can improve the mathematical literacy skills of grade XI students. Modules are teaching materials that can help students in the learning process. The ability of mathematical literacy is the ability to apply mathematics to mathematical problems in everyday life. In this study, researchers used the RME approach where an approach that connects mathematics in everyday life problems. So that the availability of this module can help students improve their mathematical literacy skills. RME-based modules are said to be feasible to use if they meet three criteria, namely valid, practical, and effective. In the results of the research analysis, 1) the module was declared very valid after a revision with a large percentage of 93.00%, 2) with an average student questionnaire response results 88.67 in the limited test and 77.67 in the field test so that the module was declared practical, then 3) completeness of student learning (CSL) of 98.00 in the limited test with effective criteria and 90.00 in the field test with effective criteria. In addition, the Personalized Gain Test is used to find out how effective RME-based learning modules can improve students' mathematical literacy skills. 4) The results of the analysis of the Gain test stated 0.80 with high information. This means that RME-based learning modules are truly said to be effective in increasing students' mathematical literacy ability.
ANALISIS EFIKASI DIRI DAN HASIL BELAJAR BERBASIS E-LEARNING PADA MAHASISWA PROGRAM STUDI PENDIDIKAN MATEMATIKA
Authors: Seto Stefania Baptis , Suryani Lely , Bantas Maria Goretty Diciloam
Published: October 2020

The purpose of this study is to see the relationship between self-efficacy and e-learning-based learning results in students of semester 4 of Flores university mathematics education study program. The research method used in this study is quantitative research, with linear regression analysis using SPSS with a random sample of 40 fourth semester students. The data analysis techniques used are the Prerequisite Test (Kolmogorov–Smirnov Normality Test) and its research Hypothesis test using Pearson Bivariate correlation analysis with the help of SPSS. The results of this study show self-efficacy (X) has a positive influence on e-learning based Learning Results (Y) known from the results of correlation analysis obtained from the value of R count to X to Y of 0.895 and the value of significance between X to Y obtained two asterisks (**) so that there is a positive influence with a significance level of 1%. In other words, better or better self-efficacy will increase the learning outcomes of the students themselves.
EFEK PELATIHAN PADA PENINGKATAN KEMAMPUAN DESAIN GRAFIS, SABLON, DAN PERCETAKAN
Authors: Rini Nova , Darda Ahmad , Abdulah Budiman , Febrianti Wenty , Julianti Pujihastuti Dwi
Published: October 2020

Tujuan dari penelitian ini adalah untuk mengetahui kemampuan desain grafis, sablon dan percetakan kepada para pemuda dan pemudi RW 04 Kelurahan Pasar Manggis Kecamatan Setiabudi melalui workshop dan pelatihan desain grafis, sablon dan percetakan yang dilakukan dilingkuangan RW 04. Metode penelitian yang digunakan dalam penelitian ini adalah metode survei dengan menggunakan pendekatan deskriptif analisis melalui penyebaran kuesioner terhadap peserta workshop dan pelatihan desain grafis, sablon, dan percetakan, dimana subjek penelitan dalam penelitian ini adalah pemuda dan pemudi RW 04 Kelurahan Manggarai, Kecamtan Setiabudi Jakarta Selatan, dengan menggunakan analisa data melalui uji beda paired sample test. Hasil dari penelitian ini menunjukan bahwa ada pengaruh nya pelatihan desain grafis, sablon dan percetakan yang dilakukan terhadap peningkatan kemampuan para peserta pelatihan, meskipun tidak terlalu signifikan.
EFEKTIVITAS PENEMPATAN PEGAWAI NEGERI SIPIL DI DINAS PENDAPATAN, PENGELOLAAN KEUANGAN DAN ASET DAERAH KABUPATEN BANYUASIN
Authors: Sahirrudin Sahirrudin
Published: October 2020

Employees are the driving force of the organization to realize its functions and achieve predetermined goals. At this time when the perceived challenges are getting more and more complex, the desire of public organizations to increase competitiveness demands to improve the quality of employees who are proactive to any turmoil and change. Thus, it can be said that the success of an organizational goal is very much dependent on the man behind the gun.This study used quantitative research approach with the level of descriptive explanation. The method used in sampling is a method of sampling of cencus or total anumeration complete the data collection method that takes each element of the population or characteristics present in the population. So the sample in this study are all permanent employees or the Civil Service Revenue Office For Management of Regional Revenue, Finance and Assets Banyuasin District until 2013. That as many as 37 people. Data used in this reseach is the primary data and secondary data. While data collecting techinque done with the method of questionnaire, observation and documentation. The data analysis techique is done by using descriptive statistical calculations. Such data can be tested by determining the answers in the questionnaire scores, where scores were divided into 4 categories, using a likert scale, to determine whether whether the placement of human resources in the Revenue DPPKAD Banyuasin District classified as very affective, effective, ineffective or very ineffective. The results showed that the placement of human resources in the Revenue Office For Management of Regional Revenue. Finance and assets Banyuasin district, including in the category overall quite effective. It is seen from the weights for the overall indicator is based on the gradation of 102.7 which made the score showed that the level of effective of the placement of human resources in the Revenue Office For Management of Regional Revenue, Finance and Assets Banyuasin Regency effective in a category, indicators used in research on the effectiveness of placments in the Revenue Office For Management of Regional Revenue,  Finance and Assets Banyuasin consists of four indicators namely Morality, aggression, leadership, and human relations.
ANALISIS PENGARUH BUDAYA ORGANISASI DAN KUALITAS KERJA TERHADAP KETERIKATAN PEGAWAI GENERASI Y
Authors: Paramita Amalia Paramita Destya , Kartika Lindawati
Published: October 2020

Otoritas Jasa Keuangan adalah lembaga pengawas IJK yang dibentuk berdasarkan UU No. 21 Tahun 2011 melalui pemindahan tugas pegawai BAPEPAM-LK dan BI ke OJK serta dari proses rekrutmen. Tahun 2016–2017 keterikatan pegawai mayoritas berada di level “kerja sama menyenangkan” yang dinilai berpeluang meninggalkan lembaga. Oleh sebab itu, diperlukan pemeliharaan keterikatan pegawai melalui internalisasi nilai budaya dan faktor kualitas kehidupan kerja. Tujuan penelitian menganalisis persepsi budaya organisasi, kualitas kehidupan kerja, dan keterikatan serta pengaruh dominan nilai budaya dan faktor kualitas kehidupan kerja terhadap keter-ikatan pegawai milenial. Penelitian menggunakan metode analisis deskriptif dan SEM-PLS. Persepsi pegawai mengenai budaya organisasi, kualitas kehidupan kerja, dan keterikatan mayoritas sangat baik. Hasil analisis SEM-PLS menunjukkan nilai profesionalisme dan sinergi, serta faktor penyelesaian konflik merupakan indikator dominan yang berpengaruh signifikan terhadap keterikatan pegawai pada dimensi pekerjaan dan lingkungan kerja.
PENGARUH KUALITAS PRODUK DAN BRAND IMAGE TERHADAP LOYALITAS PELANGGAN (Studi Empiris Pada Konsumen Wardah di Gerai Pusat Grosir Cililitan)
Authors: Wijayani Tri , Prambudi Bono
Published: October 2020

The purpose of this research is to find out the influence of product,brand image partial and simultaneous to the customer loyalty of product cosmetik Wardah. The data collected using the Rao pubra formula invloing 100 respondents which is Wardah cosmetik customers. Metodology this research is casual relation with test validity, reability tets, classic assumption test, correlation test, multipe linear regression test, t-test, F-test, and determinants. Base on result of reseach partial know that product quality (X1) influence on custemers loyality Wardah cosmetik, brand image (X2) not influence on custemer loyalty Wardah cosmetik. The qualty of product of the simultaneous effect on custumer loylity. The better the Product Quality, the Customer Loyalty will increase and the worse the Product Quality, the Customer Loyalty will decrease. The better the Brand Image the Customer Loyalty is increasing and the worse the Brand Image the customer loyalty will decrease.
PENGARUH LIFESTYLE DAN KUALITAS PRODUK TERHADAP KEPUTUSAN IMPULSE BUYING KONSUMEN SHOPEE GENERASI Z
Authors: Angela Veliana , Paramita Eristia Lidia
Published: October 2020

Perilaku konsumen saat ini berubah sesuai dengan gaya hidup era modern saat ini. Dengan adanya kemajuan teknologi semua menjadi serba praktis. Perubahan gaya hidup manusia saat ini bergeser dari yang berbelanja secara offline menjadi serba online. Sekarang e-commerce mengalami perkembangan secara pesat, terutama pada Shopee. Banyak konsumen berbondong-bondong berbelanja online melalui Shope. Selain praktis juga hemat waktu dan tenaga. Penelitian ini bertujuan untuk menguji pengaruh lifestyle dan kualitas produk terhadap keputusan impulse buying pada konsumen Shopee generasi Z. Data primer dikumpulkan melalui penyebaran kuesioner kepada 220 responden. Teknik sampling yang digunakan adalah purposive sampling dengan kriteria sebagai berikut: (1) Konsumen remaja generasi Z yang aktif menggunakan aplikasi Shopee; (2) Pernah melakukan transaksi pembelian pada platform e-commerce terutama Shopee; (3) Remaja generasi Z yang rentang usianya 17-25 tahun atau yang lahir pada tahun 1995-2003. Berdasarkan hasil pengujian diperoleh hasil  adanya pengaruh yang signifikan dengan arah positif dari variabel lifestyle terhadap variabel impulse buying. Serta, terdapat pengaruh yang signifikan dengan arah positif antara kualitas produk  terhadap impulse buying.
Entry Monitoring System
Authors: Sivakuma Dr. P. , Sundararajan Dr. R. , Sree B. Navya , Varsha P. Mohana , Varshini K. Siva , Harinidevi V.
Published: October 2020

In many times we have encountered the entry of strangers pretending as parents, entering into college premises and creating issues. To avoid these kinds of issues, security guards and surveillance cameras alone are not enough and this cannot be controlled unless the entry of people record is computerized and details of the person are recorded. In this computerized system, software is created to enter the details and the reason for the visitor to visit. In this software, the details of the visitor will be updated in a secure manner and be stored for any future reference. If the visitors have vehicles, the vehicle details are also should be given in the request page. In this computerized method, all the details will be given in prior by the guest and will be saved securely for future reference. The entry monitoring system will import details from the administrative data processing office, the affirmed work power database as an essential inquiry table. In the end, we can know all the details about the visitors like their purpose to visit, the person they like to meet, the duration of their stay inside the campus, everything stored in our database securely in case of ant future needs.
Simultaneous Uterine Carcinosarcoma and Endometroid Ovarian Carcinoma in a 21-year old woman
Authors: Voronova Anna
Published: October 2020

Poster presented at Forum for Interdisciplinary Research in Medicine, Science & Technology Conference, Moscow 2020
Peer reviewed by JS Bamrah, Ananthakrishnan Raghuraman, Soumit Dasgupta & Jyothi Srinivasan
Maisto pramonės technologinių įrenginių gamybos įmonės veiklos metu susidarančių atliekų analizė ir prevencijos būdai
Authors: Černiauskas Giedrius , Kruopienė Jolita
Published: October 2020

Visose gamybinėse įmonėse susidaro tam tikrų gamybinių ir buitinių atliekų. Atliekų tvarkymas ir prevencija yra neatsiejama įmonės
veiklos dalis. Visuose gamybose procesuose turi būti atsižvelgta ir į tai, kaip sumažinti gaunamų atliekų kiekį arba jį visai eliminuoti. Straipsnyje
analizuojama maisto pramonės technologinių įrenginių gamybos įmonė. Pasirinktoje įmonėje buvo sudaryta procesų medžiagų ir energijos srautų diagrama,
surinkti įmonės vedamos statistikos duomenys, taip buvo išskirtos dvi pagrindinės įmonėje susidarančios atliekos – popierius ir metalas (AISI304 ir
AISI316 markių nerūdijantis plienas). Atlikus tiriamosios įmonės analizę, buvo pasiūlyta atliekų prevencijai tinkamas sprendimas: popierinius brėžinius
pakeisti į skaitmeninius. Atlikus būvio ciklo vertinimą nustatyta, kaip keisis poveikis aplinkai, jei būtų įdiegtas šis sprendimas. Nustatyta, kad
naudojant skaitmeninius brėžinius vietoje popierinių, poveikis aplinkai labai stipriai sumažėtų. Taip pat nustatyta, kad pagrindinė metalo atliekų
gamyboje susidarymo priežastis yra neefektyvus lazerio naudojimas ir brokas, susijęs su standartų neatitinkančiais technologiniais mazgais.
Hidroksiapatito sintezė panaudojant fosfogipso atliekas
Authors: Jakubauskaitė Viktorija , Zeringytė Milda , Zukauskaitė Audronė
Published: October 2020

Gaminant fosforo rūgštį susidaro fosfogipso (PG) atliekų, kurių susidarymo išvengti neįmanoma, todėl nuolat ieškoma būdų, kaip būtų galima
PG panaudoti. Fosfogipsas gali būti pritaikomas statybinių rišamųjų medžiagų gamyboje, tačiau ieškoma ir naujų pritaikymo sričių, pavyzdžiui, iš fosfogipso gali
būti sintetinamas hidroksiapatitas. Hidroksiapatito sintezė iš fosfogipso atliekų turi dvigubą naudą – sintezės metu naudojamos atliekos sukurti naujam produktui,
o pats hidroksiapatitas gali būti pritaikomas nuotekų valymui nuo nepageidaujamų priemaišų. Iš hidroksiapatito gali būti gaminami filtrai, kurie gerai adsorbuoja
fluorą, sunkiuosius metalus, taip pat ir dažų likučius.Be to, švarus hidroksiapatitas gali būti naudojamas medicinoje. Šio eksperimento metu buvo sintetinamas
hidroksiapatitas keičiant sintezės sąlygas, buvo susintetinti 8 bandiniai siekiant išrinkti optimalias sintezės sąlygas. Buvo įvertintos bandinių fizikinės
(drėgnis, bandinių pH vertė po sintezės) savybės ir cheminė sudėtis. Svarbiausias rodiklis, nusakantis hidroksiapati-to kokybę, yra kalcio ir fosforo santykis.
Šis santykis turi būti toks pats kaip žmogaus kauluose – 1,677(7). Nustatyta, kad didžiausiu Ca/P santykiu (1,68) pasižymėjo bandinys, gautas atliekant sintezę
4 h be maišymo, esant 0,1 bar slėgiui uždaroje sistemoje. Tyrimo metu susintetintuose bandiniuose sunkiųjų metalų kiekis neviršija hidroksiapatito kokybę
apibūdinančiame standarte nurodytų normų.
Biodujų koncentracijos pokyčio fotobioabsorberyje matematinis modeliavimas
Authors: Juškaitė Loreta , Zagorskis Alvydas
Published: October 2020

Biologiniai biodujų valymo metodai pasaulyje vis plačiau tiriami bei taikomi. Nustatyta, kad naudojant mikrodumblių
kultūras biodujos valomos nuo jose esančių teršalų, pavyzdžiui, anglies dioksido. Darbo tikslas – teoriškai įvertinti biodujų sudėties
pokyčius fotobioabsorberyje su mikrodumblių suspensija. Darbe nagrinėtas biodujų burbuliukų kilimo greitis fotobioabsorberio modelyje
remiantis Hadamardo-Rybczynskio lygtimi. Naudojant programinį paketą Com-sol Multiphysics nustatytoa biodujose esančių teršalų koncentracijos
priklausomybė nuo bioterpės dinaminio klampumo. Įvertintas biodujų koncentracijos pasiskirstymas per visą kolonėlės skerspjūvio plotą.
Modeliavimo rezultatai parodė, kad biodujose esančių teršalų koncentracija artėjant prie fotobioabsorberio sienelių mažėja. Didesnis
koncentracijos kritimas fotobioabsorberio viršuje parodo didesnį biodujų masės perdavimą į tirpalą.
LIFE CYCLE SUSTAINABILITY ASSESSMENT FOR MULTI-CRITERIA DECISION MAKING IN BRIDGE DESIGN: A REVIEW
Authors: Navarro Ignacio Javier , Penadés-Plà Vicent , Martínez-Muñoz David , Rempling Rasmus , Yepes Víctor
Published: October 2020

Sustainable design of infrastructures has become a major matter of study since the recent establishment of the Agenda 2030.
This paper provides a systematic literature review on the use of multi-criteria decision making techniques used so far for the sustainable design
of bridges. Special attention is put as well on how the reviewed studies assess the sustainable performance of bridge designs along their life cycle
from the economic, the environmental and the social perspective. Although SAW and AHP are recurrently used in the sustainable assessment of bridges,
the analysis of the most recent articles show that the application of TOPSIS and PROMETHEE techniques are gaining increasing relevance for such purpose.
Most of the studies focus on the research of the construction and the maintenance stage of bridges. However, a need for further analysis is identified
when it comes to the assessment of the impacts resulting from the End of Life cycle stage of bridges from a sustainable point of view. The use of
intuitionistic and neutrosophic logic have been detected as emerging alternatives to the fuzzy approach of decision making problems.
Drug Use and High-risk Sexual Behavior among School-Going Adolescents in Nigeria
Authors: Amoo Emmanuel , Adekeye Olujide A. , Omumu Florence , Akinpelu Olubunmi O. , Ajayi Mofoluwake P. , Olawande Tomike , Adeusi Sussan O.
Published: October 2020

BACKGROUND: Sexual risk behavior and drug abuse among adolescents and youths remained perpetual topical issues of focus in most developmental programs related to developing countries, especially in Nigeria, where the school-going adolescents constitute more than half of the youths. The high level of teenage pregnancy and sexual violence such as abuses and other harmful trajectories including STIs and HIV is increasingly reported than the pre-2000s.
AIM: This study focuses on underscoring the variation in risky sexual behavior among school-going users and non-users of drugs. It also analyzed the predisposing factors of drug use among school-going adolescents in Nigeria.
METHODS: In combination with problem behavior theory, the research draws data (n = 11,799) from the 2012 National HIV and AIDS and Reproductive Health Survey (NARHS Plus II) collated by the Federal Ministry of Health in Nigeria with support from the Department for International Development and United States Agency for International Development, to underscore the self-reported sexual risk behavior among students who are users and non-users of drugs.
RESULTS: The result revealed that 32.5% (male) and 33.4% (female) use drugs. More than half of the respondents reported that they have engaged in sexual intercourse, 27.3% (male) and 31.8% (female) have had ≥2 lifetime sexual partners. There is higher odds ratio (OR) of risky sexual behavior among students that have ever used drugs or taken alcohol (OR = 2.2, 95% CI [1.8–2.8]) for male and (OR = 2.1, 95% CI [0.83–2.03]) for female.
CONCLUSION: The study concludes that continued exposure of school-going youths to drugs or alcohol may pose serious challenge of risky sexual behavior and also severe threat to initiatives on zero new HIV infections or zero new AIDS death in Nigeria. The authors recommend that campaign to discourage drug or alcohol use should be intensified and introduced to all schools.
Metoclopramide-OROS Dispersible Tablets Optimized Formula Bioavailability Study
Authors: Samran Samran , Tanjung Hari Ronaldo
Published: October 2020

BACKGROUND: Bioavailability and bioequivalence studies required by regulations to ensure therapeutic equivalence between a pharmaceutically equivalent test product and a reference product.
AIM: This study aimed to evaluate the bioavailability performance between the optimum formula of OROS dispersible tablet-metoclopramide dosage forms (FCL-6) and the Primperan® as the reference product.
METHODS: The FCL-6 formula was design by simplex lattice design model with a three components mixture of excipients: Solid tapai extract, corn starch, and Avicel. The optimum formula of OROS dispersible tablet (ODT)-metoclopramide consists of solid tapai extract (27.038 mg), corn starch (27.407 mg), and Avicel (53.555 mg), metoclopramide hydrochloric acid (HCl) (10.00 mg), LH-11 (22.50 mg), aspartame (5.00 mg), talcum BP (3.00 mg), and Mg stearate (1.50 mg). The in vivo test was done by cross-over design method using six rabbits. The level of metoclopramide concentration from in vivo test was measured by high-performance liquid chromatography instrument.
RESULTS: The study revealed that the tmax, Cmax, and area under curve (AUC) of ODT-metoclopramide FCL-6 were 60 min, 1.95 ± 0.13 μg/mL, and 1118.20 ± 150 μg/mL. min consecutively. The Cmax and the concentration of the drug absorbed in the blood (AUC) of ODT-metoclopramide were larger than Primperan® tablets. Statistical data of the optimized ODT-metoclopramide compared with Primperan® showed that the Cmax and AUC significance values were <0.05 (p < 0.05).
CONCLUSION: The optimized formula of ODT-metoclopramide revealed a better characteristic of Cmax and AUC concentration compared with Primperan®. The optimized ODT-metoclopramide with tapai extract was found to be promising to improved bioavailability of metoclopramide.
The Effect of Salam Leaf (Syzygium polyanthum [Wight] Walp.) Extract on Inflammation in Rat Model of Acute Coronary Syndrome
Authors: Hasan Refli , Lindarto Dharma , Siregar Gontar Alamsyah , Mukhtar Zulfikri
Published: October 2020

AIM: The aim of the study was to determine the effect of Salam leaf extract on regenerating islet-derived protein 3 β (Reg3β) and C-reactive protein (CRP) in cardiomyocyte of rat model of ACS.
METHODS: Thirty-six male Wistar rats were divided into three groups: Negative control group, positive control group (ACS-induced group), and treatment group (ACS-induced group with Salam leaf administration). Macroscopic appearance and histopathology examination were done to ensure the occurrence of infarction. Reg3β and CRP levels were measured and compared between the positive control group and treatment group.
RESULTS: There were significantly lower Reg3β and CRP levels in the treatment group than in the positive control group from day 4 to day 14.
CONCLUSION: These data suggest that a Salam leaf extract can improve inflammation by decreasing Reg3β and CRP levels in rat model of ACS.
Anti-Inflammatory Activity of Rhaphidophora pinnata (L.F) Schott Leaf Extract
Authors: Sumaiyah Sumaiyah , Masfria Masfria , Dalimunthe Aminah
Published: October 2020

BACKGROUND: Cancer growth is influenced by many factors and in general it is an interaction between gene factors and environmental factors, especially the microenvironment that exists around cancer. The inflammatory response plays a decisive role in various stages of cancer growth.
AIM: The aim of this study was to determine the anti-inflammatory activity of ethanol extract of Rhaphidophora pinnata leaves.
METHODS: R. pinnata leaf extract was obtained by percolation method using 96% ethanol as the solvent at room temperature. Anti-inflammatory activity was determined based on the paw edema method. Thirty male albino mice were treated orally with sodium carboxyl cellulose suspension (as negative control group), R. pinnata leaf extract (35, 70, 140, and 280 mg/kgBW), and diclofenac (as positive control group), 60 min before 0.2 mL 1% carrageenan injection. The paw thickness was measured using plethysmometer before injecting the carrageenan and after 1, 2, 3, 4, 5, and 6 h.
RESULTS: The subplantar injection of carrageenan caused a time-dependent paw edema in the mice. Oral administration of R. pinnata leaf extract inhibited paw swelling at 1, 2, 3 4, 5, and 6 h after carrageenan injection. R. pinnata leaf extracts doses of 35, 70, 140, and 280 mg/kgBW gave a percentage inhibition of 56.56%, 56.18%, 62.77%, and 49.30%, respectively. The effective dose of R. pinnata leaf extract as an anti-inflammatory was 140 mg/kgBW.
CONCLUSION: Ethanol extract of R. pinnata leaf has anti-inflammatory activity in male albino mice.
Allele Frequency of Carbamazepine Major Efflux Transporter Encoding Gene ABCB1 C3435T among Javanese-Indonesian Population
Authors: Istikharah Rochmy , Hartienah Septiayu D. , Vitriyani Sandra , Ningrum Vitarani Dwi Ananda
Published: October 2020

BACKGROUND: Genetic variations in ABCB1 gene that encodes P-glycoprotein, the main transporter in the efflux of carbamazepine (CBZ) from the brain cells, can lead to pharmacodynamic and pharmacokinetic variability. Polymorphism of C3435T is widely known to cause protein overexpression that contributes to an increased risk of CBZ resistance.
AIM: This study determined the allele frequency distribution of ABCB1 C3435T gene in healthy subjects of the Javanese population as a major ethnic group in Indonesia.
METHODS: This cross-sectional study involved 100 healthy volunteers who fulfilled the inclusion criteria. The genotype analysis to detect polymorphism in the targets employed the polymerase chain reaction-restriction fragment length polymorphism method with 5’-TGCTGGTCCTGAAGTTGATCTGTGAAC-3’ as the forward primer and 5’-ACATTAGGCAGTGACTCGATGAAGGCA-3’ as the reverse primer.
RESULTS: The frequency of subjects with C allele in ABCB1 C3435T gene reached 53%, higher than that with T allele.
CONCLUSION: This finding was nearly the same as that in studies of the populations in China, Turkey, and four countries in the South European continent. It is recommended to conduct further research on the correlation between C3435T polymorphism and CBZ dose variability to provide a comprehensive approach to epilepsy management in patients receiving CBZ.
Timing of Surgery for a Tibial Pilon Fractures – Search for a Wise Moment
Authors: Hasani Ilir
Published: October 2020

BACKGROUND: Biphasic treatment of pilon fractures has been accepted as standard modality of care.
AIM: The aim of the present study was to evaluate the effect of timing of definitive surgery for closed pilon fractures on the short-term functional outcome.
MATERIALS AND METHODS: Prospective study focused the patients suffering pilon fracture that has undergone treatment in a biphasic manner. Initially, spanning external fixator was applied, while the definitive osteosynthesis was performed within the next several days, in accordance with surgeon’s knowledge. The final functional outcome was evaluated using the American Orthopedic Foot and Ankle Society Ankle-Hindfoot Score.
RESULTS: Forty-two patients were included in the study. Mean time passed from injury to definitive surgery was 11.0 ± 3.4 days. Mean value of the functional score was 86.54 ± 13.2 points, with no significant differences with regard to the demographics and injury features. Pearson correlation coefficient demonstrated negative significant correlation between timing of definitive surgery and functional outcome (r = −0.428, p = 0.033). Complications were noted in 16% of the patients.
CONCLUSION: Definitive surgery should be planned as soon as possible, once the surgeon considers the soft-tissue status acceptable for surgery. Injudicious postponing has a negative effect on the short-term functional outcome.
Hepcidin and its Related Hematological Biomarkers of Anemia in Children on Hemodialysis: Role of Carnitine Deficiency
Authors: El-Toukhy Safinaz E. , Fadel Fatina , Elshamaa Manal , El-Saeed Gamila S. M. , Abdelaziz Hanan , Elsonbaty Marwa , Elghoroury Eman A. , Hamza Eman , Atef Soha
Published: October 2020

BACKGROUND: Anemia is one of the most common complications in end-stage renal disease (ESRD) patients. Hepcidin is a hormone that regulates iron homeostasis in patients with ESRD. Carnitine deficiency is commonly seen in hemodialysis (HD) patients.
AIM: This study aimed to investigate the relationship between hepcidin and inflammatory and other anemia markers in children with ESRD and to evaluate the association of carnitine deficiency with anemia in these patients.
SUBJECTS AND METHODS: Thirty pediatric patients with ESRD undergoing HD, and thirty healthy, age- and sex-matched children served as controls were included in the study. Serum levels hepcidin, iron status, high-sensitivity C-reactive protein, and total carnitine were measured.
RESULTS: Statistically significant increases in serum levels of hepcidin (100.7 ± 0.99 ng\ml vs. 77.43 ± 0.8 ng\ml, p = 0.000), was found in HD children as compared to healthy controls. Statistically significant increase in serum levels of hs-CRP (3.94 ± 0.19 mg/l vs. 1.36 ± 0.07 mg/l, p = 0.04) was found in HD children as compared to healthy controls. However, serum levels of carnitine (29.59 ± 2.46 μmol/L vs. 36 ± 2.39 μmol/L, p = 0.000) showed statistically significant decreases in HD children as compared to healthy controls positive correlation was found between hepcidin and hs-CRP (r = 0.059, p = 0.042). Furthermore, a positive correlation was present between serum carnitine levels and serum iron levels (r = 0.651, p = 0.042).
CONCLUSION: Serum hepcidin may be a more useful biomarker of functional iron deficiency in children on HD. The efficacy of carnitine treatment for children on HD with carnitine deficiency and its effect on anemia needs to be studied.
Diagnosis Performance of Cerebral Venous Thrombosis with Magnetic Resonance Imaging and Magnetic Resonance Venography in Zahedan (Southeast of Iran): A Series of 57 Patients
Authors: Sanei Sistani Sharareh , Khajeh Ali , Amirifard Hamed , Mohammadi Mahdi , Derakhshandi Hajar , Ghahderijani Bahareh Heshmat
Published: October 2020

BACKGROUND: Cerebral venous sinus thrombosis (CVST) is a scarce disease with poor prognosis and its diagnosis often challenges physicians due to nonspecific symptoms and widespread clinical manifestations.
AIM: To investigate the findings of magnetic resonance imaging (MRI) and magnetic resonance venography (MRV) of patients with CVST diagnosis in Ali Ebne Abitaleb Hospital in Zahedan during 2013–2016 and to evaluate imaging pitfalls involving in late diagnosis, complications, and even death.
METHODS: This retrospective descriptive study was done on 57 patients with confirmed CVST during 2013–2016 in Ali Ebne Abitaleb Hospital in Southeast of Iran (Zahedan). The MRI and MRV findings and related diagnostic pitfalls were evaluated. Twenty-one patients are pediatrics and 33 patients are adults.
RESULTS: Of 57 patients, evidences of cerebral edema were found in 33 patients, among whom 2 patients showed parenchymal edema (cerebral edema) without infarction, and 31 patients exhibited parenchymal edema with infarction. The frequency of involvement in descending order was as followed; transverse sinus (96.49%), sigmoid sinus (49.12%), superior sagittal sinus (29.82%), jugular vein (19.29%), internal cerebral veins (7.01%), straight sinus (5.2%), and cortical veins (5.2%). Diagnostic pitfalls were also found in 8 patients. Seven patients exhibited acute and subacute thrombosis mimicked normal sinus flow void in T2-weighted images. No filling defect was seen on gadolinium-enhanced T1-weighted image in the other patient due to the sub-acute phase of thrombosis.
CONCLUSION: The delayed diagnosis of CVST originating from nonspecific clinical features and diagnostic imaging pitfalls can result in poor outcomes in patients. To prevent the diagnostic pitfalls, the clinician should give a brief history and clinical data and radiologist(s) should interpret the findings in addition to the use of advanced MR sequences.
Farsi Translation and Cultural Adaptation of Psychosocial Impact of Dental Esthetics Questionnaire and Evaluation of its Validity and Reproducibility
Authors: Golshah Amin , Esfandeyari Haddis , Nikkerdar Nafiseh , Imani Mohammad Moslem , Safaei Mohsen , Sharifi Roohollah , Mozaffari Hamid Reza , Moradpoor Hedaiat
Published: October 2020

AIMS: This study aimed to translate the psychosocial impact of dental esthetics questionnaire (PIDAQ) to Farsi and assess its cultural adaptation, validity, and reproducibility.
MATERIALS AND METHODS: The PIDAQ was translated to Farsi by experts fluent in Farsi and English. It was then back-translated to English by another expert blinded to the original version. The translated version was administered among 40 patients to assess its face validity and content validity. Final version of the questionnaire along with the index of orthodontic treatment need (IOTN) and the perception of occlusion scale (POS) was administered among 400 patients (224 females, 176 males) to assess their need for orthodontic treatment. To assess its validity, the mean score of PIDAQ was evaluated in different ranges of IOTN-esthetic component (IOTN-AC), IOTN-dental health component (DHC), and POS. To assess its convergent validity, the PIDAQ, IOTN-AC, IOTN-DHC, and POS scores were evaluated. Its construct validity was evaluated by confirmatory and exploratory factor analysis. Its internal consistency was evaluated using Cronbach’s alpha and the split-half method. Its test-retest reliability was evaluated by calculating the intraclass correlation coefficient (ICC).
RESULTS: The Cronbach’s alpha was found to be 0.900–0.945 for the questionnaire domains, which showed good reliability. The ICC for the four questionnaire domains was 0.926, which was excellent. IOTN-DHC, IOTN-AC, and POS had significant correlations with the questionnaire domains.
CONCLUSIONS: The Farsi version of PIDAQ has optimal validity and reliability and can be used for assessment of the dental esthetics-related quality of life of Iranian young adults.
Heavy Metal Contributions on Human Skin Disease near Cement Plant: A Systematic Review
Authors: Rauf Annisa Utami , Mallongi Anwar , Astuti Ratna Dwi Puji
Published: October 2020

AIM: The aim of this systematic review was to investigate heavy metal roles at skin disease of humans in the cement industrial area.
METHODS: All research reporting a specific heavy metal, which could be increasing the risk of the disease, cause cement induced to skin. Fourteen selected articles from our inclusion criteria rated using eight quality-appraisal criteria derived from Strengthening the Reporting of Observational Studies in Epidemiology checklist and following preferred reporting items for systematic reviews and meta-analyses methodology.
RESULTS: We performed a systematic review of published articles between 2009 and 2019 from ten case–control, two cohort, one ecological study, and one cross-sectional study showed the heterogeneity of the study design. The studies are focusing on the relationship between heavy metal and skin disease that appeared in cement plant areas such as dermatitis, skin cancer, eczema, and other allergies. Chromium, nickel, cobalt, zinc, cadmium, mercury may present and play an important role for human skin disease.
CONCLUSION: Heavy metals have been found in the skin of human living and work around the cement industry. Chromium, cobalt, and nickel are almost certainly present in every case of dermatitis and eczema. Signs and mild symptoms of skin disease include redness, itching, starch, and dryness. Elements such as cadmium, lead, and mercury usually are found in chronic skin disease (psoriasis and skin cancer) on a biologic test. These findings should raise an important concern and recommendation policy for controlling raw materials contains heavy metal in cement industrial areas and proper protection for workers and non-worker.
A Unique Anatomical Variant of the Levator Scapulae Muscle: A Case Report
Authors: Fakoya Adegbenro Omotuyi John , De Filippis Samantha Michelle , D’Souza Aaron , Arizmendi-Vélez Gabriela , Rucker Ariel Jazmine , Satyadev Nihal , Ravikumar Nithin , Afolabi Abayomi Gbolahan , McCracken Thomas , Otohinoyi David
Published: October 2020

Musculature variations in the head and neck are typically observed in cadaveric dissections. Some of these variations could involve the levator scapulae muscle, which may lead to cervical and postural misalignment. The levator scapulae function to elevate the scapula and rotate it downward. In this case report, we present an 88-year-old male cadaver diagnosed with thoracic kyphosis having a double-bellied levator scapulae, originating from the transverse processes of C1-C4 and the mastoid process. This abnormality, not found elsewhere in our search of literature, can give physicians insight into upper back pain management and surgical navigation of the posterior cervical and upper back regions.
Experimental Model of Pancreonecrosis Induced by Auto-bile Injection
Authors: Abramov Grigoriy , Shakeyev Kairat , Tusupbekova Maida , Tagaev Ermek , Shestakov Dmitriy , Zhumanbaev Sanzhar
Published: October 2020

AIM: The aim of the study is to create an easily reproducible experimental model of pancreonecrosis with the least aggressive technique of the operation.
METHODS: Twenty-two outbred rabbits of comparable weight and age were included in the study. The animals were removed from the experiment 12, 24, and 48 h after the injection of auto-bile into the parenchyma of the pancreas.
RESULTS: After completion of the experiment, rabbit pancreas was extracted, macroscopic and microscopic description was given.
CONCLUSION: According to the results of the study, the proposed model is considered as consistent for reproducing pancreonecrosis in an experiment with less aggressive surgical technique.