bluuebunny/crossref_metadata_2025 huggingface dataset:
Breast Milk for Neonatal Vaccination Pain
Authors: S Sujatha , Samson Rebecca , Sundaresan
Published: May 2022

A prospective, double-blinded (caregiver, researcher) randomised experimental study was conducted at the postnatal ward of a tertiary care hospital at Puducherry to identify the effect of twin intervention on pain among neonates receiving Bacillus Calmetteguaorine (BCG) vaccine. The outcome variable of pain level was assessed by using the Neonatal and infant pain Scale (NIPS) in terms of behavioural changes in behaviour and haemodynamic behaviour and variables like respiratory rate (RR), heart rate (HR), oxygen saturation (SpO2). One hundred and forty-five neonates fulfilling the inclusion criteria were randomly recruited into the study after informed parental consent. One ml of expressed breast milk (EBM) was given to the neonates by sterile syringe 2 min before BCG vaccination and the newborn kept in facilitated tucking position (FT) during vaccination procedure. The behavioural changes of neonates, duration of cry time and selected physiological parameters were recorded before BCG vaccination and after at 0, 3 and 5 min. It was found that the twin Intervention was effective in reducing the level of pain. The mean pain level for EBM group was 3.089 and for control study group it was 3.6. The median crying time was 53.511seconds in EBM at p<0.001 which is less when compared with the control group. To conclude, the “twin intervention” (FT& EBM) significantly reduces pain in neonates while they receive BCG vaccination.
Prevalence of Protein Energy Malnutrition (PEM) and its Association with Eruption of Primary Teeth
Authors: Khound Smriti Rekha , Das Swargajyoti
Published: May 2022

Protein energy malnutrition (PEM) is one of the most common undernutrition conditions leading to high mortality and morbidity rate among children influencing greatly the skeletal and dental development as well. The aim of the study was to find out the prevalence of PEM among preschool children and its association with eruption of primary teeth. The study was conducted among 500 pre-school children attending Anganwadi centres of Kamrup District (Assam), adopting cross-sectional descriptive survey design. The samples were selected by using purposive sampling technique. The height and weight of the samples were measured and values obtained were compared with WHO guidelines. Eruption of primary teeth was evaluated by oral examination. It was revealed that the overall prevalence of PEM was 37 percent, whereas stunted and wasted subjects were of 67.03 percent and 23.78 percent, respectively and 9.19 percent subjects manifested as both wasted and stunted. Among 54.97 percent subjects with PEM, eruption of primary teeth was not completed.
The Indicators of Bad Selection in Private Organizations of Bangladesh
Authors: Tamzid Mohammad
Published: May 2022

Purpose: The aim of this study is to recognize bad selection or wrongly selected employee in the organization. To do so, a variety of signs or symptoms of bad selection were described and closely reviewed in the literature.
Methodology: To quantify and discover various measures of bad selection, this study used survey methodology. Questionnaire was prepared form the construct of the literature review. Cochran's formula was used to determine the adequacy of sample size to find out the authentic result. From various Bangladeshi private organizations, a total of 418 responses were obtained from people who are involved in employee selection process for the 2020-21 year. To analyze the data frequency analysis was done for the close ended questions and content analysis was done for one open ended question.
Findings: On an average 6.09 alternatives have been chosen by the respondents from the given list of indicators of wrong hire. The finding also shows some other indicators to recognize bad selection, are offensive demeanors, apathy, and failure to lead. Originality/Value: This research demonstrates that organizations have to be careful about the signs of bad selection or wrong hire. Timely identification of the bad selection can help organization to take remedial steps and mitigate the negative consequences throughout the organization. This research may help organization to understand different indicators of bad selection
Lidl und Kaufland halten den Kurs
Authors: Stockburger Manfred
Published: May 2022

Mit 133,6 Mrd. Euro Umsatz und einem Plus von 6,6 Prozent hat die Schwarz-Gruppe im abgelaufenen Geschäftsjahr den Abstand zum Wettbewerb vergrößert. Lidl verkaufte erstmals Waren im Wert von mehr als 100 Mrd. Euro.
„Wir sind online derzeit der Letzte in der Runde“
Authors: Hofmann Janine
Published: May 2022

Hagebau baut um. Die Gruppe will mit dem „Soltauer Weg“ genannten Entwicklungsprozess online zum Wettbewerb aufschließen und Marktanteile zurückgewinnen.
Walmart schraubt Gewinnerwartungen zurück
Authors: Rennack Sebastian
Published: May 2022

Walmart verliert beim Ergebnis und kann auch beim Umsatz nur begrenzt von der Rekordinflation profitieren. Viele europäische Händler können jedoch schneller als die Teuerungsrate wachsen.
Coca-Cola gibt Gastro bei Glas-Flaschen den Vorrang
Authors: Holst Jens
Published: May 2022

Die Engpässe in der Glasindustrie zwingen Coca-Cola dazu, Prioritäten bei der Belieferung mit Glas-Gebinden zu setzen. Der Handel hat vorerst das Nachsehen – der Umsatz mit Coke-Produkten wächst allerdings trotzdem.
SanLucar strukturiert Kundenbetreuung um
Authors: Lenders Dirk , Krönert Alrun
Published: May 2022

Der spanisch-deutsche Fruchtvermarkter SanLucar nutzt den Abgang von Geschäftsführer Oliver Daniel, um sich im Traditional Market neu auszurichten. Ziel ist ein weiterhin zweistelliges Umsatzwachstum.
Kritik an Habecks Klimaprogramm
Authors: Mulke Wolfgang
Published: May 2022

Mit dem Klimaschutz-Sofortprogramm 2022 der Bundesregierung kommen auf die Wirtschaft neue Belastungen zu. Die Verbände fordern Änderungen am Entwurf.
Offener Brief zu „Gentechnikfrei“
Authors: Falker Gerrit-Milena
Published: May 2022

Der Deutsche Raiffeisenverband (DRV) warnt den Handel in einem Offenen Brief, dass die Kennzeichnung von Milchprodukten „ohne Gentechnik“ wegen des Ukraine-Kriegs unter Druck gerät.
Migros setzt ein Zeichen für Väter
Authors: Wittenhagen Julia
Published: May 2022

Migros macht sich stark für mehr Gleichberechtigung nach der Geburt eines Kindes. Ein Teil des Mutterschutzurlaubs kann samt Bezügen dem Vater übertragen werden – selbst wenn dieser ganz woanders arbeitet.
Indiens Exportstopp beunruhigt Märkte
Authors: Bach Steffen
Published: May 2022

Frankfurt a.M. Mit einem Aussetzen der Weizenexporte will Indien den eigenen Bedarf sichern. Für die neue Ernte werden Ertragsausfälle befürchtet.
Towards Sustainable Design: Influence of pandemics on Architectural Design and Urban Planning through the ages
Authors: Sebastian Sofia , K.R. Ravishankar
Published: May 2022

In the history of the built environment, interior design and urban planning have always responded to epidemics by designing architecture and urban spaces to resist the different viruses and pathogens while preventing their spread. The architectural design strategies used in the past centuries, including Modernism, were a reaction to creating pandemic-free built forms and spaces, thus creating a healthy and sustainable built environment. The Italian piazzas, modernism, minimalism, decentralization of urban cities, urban renewal, etc. were a few of the design outcomes of a pandemic-resistant environment. This research study will help architects understand and evaluate the design strategies used to achieve a healthy, sustainable built environment, thereby adding progressive layers of protection against the virus. Future-built spaces must be designed by taking into account what we’ve learned from the past and moving in the right direction toward sustainability.
Arte, educación artística y democracia
Authors: R. R. B.
Published: May 2022

No hay resúmenes disponibles.

ECA Estudios Centroamericanos, Vol. 50, No. 565-566, 1995: 1162-1166.
Egyetem születik : Szubjektív írás az elmúlt 30 évről
Authors: Szabó Péter Ottó
Published: May 2022

1990-ben, alig egy évvel a rendszerváltoztatás után, késő ősszel már hideg szél fújt, amikor két székesfehérvári fiatalember, Rockenbauer Lajos és Szabó Péter, kiszálltak a Lada 1200-as gépkocsiból valahol Budán. Meghívót kaptak a Keresztény Értelmiségiek Szövetségének megbeszélésére, ahol Andrásfalvi Bertalan, a híres néprajztudós és oktatási miniszter tartott előadást. Mit keresünk itt, és ki hívott? – tanakodtak a fehérváriak. Az előző kérdésre hamarosan, az utóbbira azonban a mai napig nem született válasz.
A gyermekvédelmi szakellátás rendszerében a gyermekotthonokban nevelkedők életútja és viselkedés-mintázatának háttere (Első rész)
Authors: Szennai Dóra
Published: May 2022

A gyermekvédelmi szakellátásban élő gyermekek fejlődésében jelentős különbséget jelent, hogy nevelőszülői hálózatban vagy gyermekotthonban nevelkednek. Utóbbiak fejlődésük egy kiemelt szakaszában család nélkül kénytelenek felnőni, kötődési hiányosságaik következményeként kiegyenlítetlen képességprofil és sajátos viselkedésmintázat jellemzi őket, ami megnehezíti oktatásban való részvételüket és előmenetelük sikerességét. Társadalmi beilleszkedésük fokozottan nehezített, melyből kitörési lehetőséget nyújthat a minél magasabb fokú iskolai részvétel és végzettség elérése. A magyar iskolarendszerben viszont az egyik legerősebb az összefüggés a tanulók társadalmi hátterének jellemzői és tanulási eredményessége között.2 Éppen azoknak a tanulóknak a legelőnytelenebb az átlageredménye, akik szociális, gazdasági és kulturális státusz szempontjából a leghátrányosabb helyzetű családokba születnek, ami minimális esélyt hagy számukra kiváló iskolai teljesítmény eléréséhez. Az összefoglaló a nemzetközi és hazai gyermekvédelmi rendszer szabályozásán és törekvésein keresztül nyújt betekintést a nehéz sorsú gyermekek életútjának állomásaiba és traumáiba, valamint próbálja feltárni a következményeként megmutatkozó atipikus viselkedésmintázatok és beilleszkedési nehézségek hátterét. Érzékenyítő célzattal irányítja a figyelmet a gyermekvédelmi szakellátáson belül a gyermekotthonokban nevelkedők viselkedésmintázatának háttértényezőire, remélve, hogy ezek megismerése mentén elfogadó szemléleti megközelítéssel teremthetnek lehetőséget az oktatásban dolgozók a gyermekek képességeinek kibontakoztatására és tanulmányi sikereik előmozdítására.
Carbapenemase Producing Klebsiella species from Hospitalised Patients at Three Referral Hospitals in Yaounde; Cameroon
Authors: Lyonga Mbamyah Emilia Enjema , Kumcho Mangum Patience , Michel Toukam , Sedena Dieudonné , Enyeji Florence Anjabie , Teukam Noupe Aime Cesar , Djuissi Modestine , Mesembe Martha Tongo , Ikomey George Mondinde , Eyoh Agnes Bedie , Gonsu Hortense Kamga
Published: May 2022

Background: Carbapenemases are the most potent beta-lactamases capable of hydrolysing all beta-lactam drugs. Data scarcity on laboratory evidence of carbapenemase producers obstructs infection prevention and effective control measures. This study aimed to detect and phenotypically characterize Klebsiella species resistant to carbapenems.

Method: A total of eighty-seven (87) Klebsiella spp. isolates were collected from three Yaounde-based tertiary hospitals over a period of twelve months (February 2019 to January 2020). The isolates were identified on API 20E and antimicrobial susceptibility testing was done according to the Kirby Bauer disc diffusion method. Carbapenem resistance was detected based on reduction in inhibition zone diameter of meropenem less than 28mm and resistance phenotypes determined by the combination disc synergy test.

Results: Four Klebsiella species were identified namely: Klebsiella pneumoniae 62/87 (71.3%), K. oxytoca 11/87 (12.6%), K. ozaenae 7/87 (8%), K. rhinoscleromatis 7/87 (8%). Klebsiella pneumoniae was most resistant to carbapenems with a considerably high number of multidrug resistant isolates 39/56 (69.6%). Patients from the 0-9 years age group were most represented 29/87 (33.3%). Carbapenemases belonging to Ambler classes A, B and D were detected as follows: KPC 2/87 (2.3%), MBL 2/87(2.3%), OXA-48 4/87 (4.6%). All four Klebsiella species were producers of KPC carbapenemase 12/87 (13.8%) and Extended Spectrum β-lactamase 68/87 (78.2%) enzymes.

Conclusion: These results revealed that more than half of Klebsiella species analysed were multidrug resistant and about a quarter in hospitalized patients at the referral hospitals were mostly KPC carbapenemase producers. This raises concerns over the need to control and confine the spread of these isolates of clinical and epidemiological importance for effective infection prevention and control.
PENGARUH BERPIKIR INDUKTIF DALAM PEMBELAJARAN GETARAN DAN GELOMBANG DIKELAS VIII SMPN BOSAR GALUGUR KECAMATAN TANAH JAWA
Authors: Surbakti Mariana , Nainggolan Irawati Kristin M. , Sitorus Parlindungan
Published: May 2022

This research aims to find out the influence of inductive thinking learning models in physics learning on Vibration and Wave Material of Grade VIII in SMPN Bosar Galugur Village, Tanah Jawa Sub-District. This type of research is a "true" experimental research with a research population that is all grade VIII junior high students in Bosar Galugur Village, Tanah Jawa Sub-District. With the Cluster Random Sampling technique, it is considered a research sample of experimental classes (13 students) and control classes (12 students). The instruments used are student results tests with multiple selection forms that have been performed through validation tests as well as student activity observation sheets. The results of the data analysis were an average score of 61.92 experiment class post-test with a standard deviation of 10.11 and an average post-test control class score of 41.66 with a standard deviation of 12.49. The hypothesis of this study was tested with a one-party t test for experiment class post test data and control classes for α=0.05 and dk=23 obtained thitung =4.48 and ttabel =1.71, with thitung>ttabel then Ha accepted and H0 rejected. Thus it can be concluded based on the above calculation results that there is a significant influence of inductive thinking learning model in physics learning on Vibration and Wave Material Grade VIII in Bosar Galugur Village of Tanah Jawa Sub-district.
PENYIDIKAN TERHADAP ANAK PELAKU TINDAK PIDANA NARKOTIKA DI KEPOLISIAN DAERAH SUMATERA UTARA
Authors: Sihaloho Pranata Royganda
Published: May 2022

This Research at the Regional Police of North Sumatra is carried out by investigators, both Polri investigators, and investigators from the North Sumatra National Narcotics Agency. Have found about this research, namely research on the factors that cause children to commit narcotics crimes, carrying out investigations against children who are perpetrators of narcotics crimes within the North Sumatra Regional Police, obstacles in investigating children who are perpetrators of narcotics crimes in the Sumatra Regional Police. The results of the study indicate that the factors that cause children to commit narcotics crimes are broken homes; lack of attention and time given to children, both in the context of education and maintenance of intimate relationships in the family; the fragility of family values ​​or norms, including the introduction of polite values; family economy that is not able to support the necessities of life, including the need to continue school or find employment, to prove their courage to carry out dangerous actions such as speeding, fighting, associating with women, to oppose or against an authority (parents, teachers, law); to lighten sexual desires and facilitate sexual intercourse
The Non-Aligned News Agencies Pool and the Paradox of Self-Sufficiency
Authors: Slaček Brlek Sašo
Published: May 2022

The article focuses on the process that led to the creation of the Non-Aligned News Agencies Pool (NANAP) and the factors that shaped its emergence. The author explains the emergence of NANAP by three groups of factors. The first were interests and strategies of Yugoslav political elites and of Yugoslavia’s Tanjug news agency. While Tanjug was interested in increasing its global reach and position on the global marketplace of news agencies, federal political elites saw Tanjug as an important tool of foreign policy. Yugoslavia was actively pushing to institutionalize informational cooperation within NAM already in the run-up to the IV. NAM summit in Algiers, even though objective conditions were deemed minimal. The second factor are changes in international relations, as NANAP emerged in the context of the institutionalization of the Non-Aligned Movement (NAM) in the 1970s and its efforts to build “self-sufficiency” in order to increase its position within the global economy and bargaining power vis-a-vis the developed countries. NANAP therefore recontextualized Tanjug’s bilateral news exchange agreements into a multilateral project of economic cooperation within NAM, aimed at strengthening mutual understanding and gaining independence from global (primarily Western) news sources. Finally, the development of NANAP was shaped by the institutional history of the movement, as NANAP was conceived and institutionalized in the mold of pre-existing forms of economic cooperation. To respect the movement’s decentralized ethos Yugoslavia had to downplay and disguise its significant degree of involvement in establishing NANAP and other forms of informational cooperation and present them as multilateral projects with a broad basis of support within NAM.
The Journalist's Action in Socialist Yugoslavia
Authors: Žnidaršič Nina
Published: May 2022

In this paper, we analyse the language game “the journalist as a socio-political worker”, which was the professional label for journalists’ action in the former socialist Yugoslavia. The text is divided into two main parts. The first part uses a historical-conceptual method to analyse the mentioned formulation in normative texts, covering programmatic and engaged texts produced at the time. This approach seeks to enter into the meaning of the term from the inside, into the pulse and spirit of the time, and above all to understand what its creators wished to achieve and communicate with this expression. We find that journalism and the journalist’s action as a socio-political worker were understood as an important political factor, as a political force on one hand contributing to the development and implementation of a new socio-political order, i.e., a socialist community based on self-management and, on the other hand, the journalist who through their own products tried to influence the broader consciousness of the masses, as manifested through the idea of the education for the new man: the self-manager. The second part of the paper complements the first since through the qualitative method of in-depth semi-structured interviews with former journalists who had been professionally active in the Socialist Federal Republic of Yugoslavia, and via their recollections, we continue to internally reconstruct the meaning, understanding and use of the formulation at that time. In particular, we observe the relationship with politics that the concept essentially contains. Empirical analysis thus led us to different conclusions: some interviewees (the minority) described the term affirmatively, that the journalist as a socio-political worker had a special mission, while most approached the use and meaning of the expression with a critical distance, namely, that the journalist as a socio-political worker was harnessed to the needs of daily politics and thereby seen as non-autonomous in their labour and actions.
Eritreja, moja dežela
Authors: Tomanić Trivundža Ilija
Published: May 2022

The article analyses the representation of distant others in Eritreja photoreporatge, which ran for ten consecutive issues in Mladina magazine between August and November 1988 and is considered to be the most extensive photoreportage ever to be published in Slovene printed media. Multimodal framing analysis, complemented by semi-structured interviews with authors, is applied to examine verbal and visual strategies for construction of otherness. Eritreja’s divergence from dominant news topics on the subject (famine and war) and its positive representations of the distant other are traced to photoreportage’s resonance within domestic political agenda (Slovene struggle against Yugoslav centralisation) and Mladina’s editorial policy (advocating freedom of speech via attacks on Yugoslavia’s public taboo topics).
Robotic-Assisted Spinal Surgery
Authors: Kumar Diksha , Wells Charlotte , Picheca Lory
Published: May 2022

The use of robotic systems to aid in surgical procedures, including spinal surgeries, has been on the rise over the past several years.

Systematic reviews and economic evaluations on the clinical and cost-effectiveness of robotic-assisted surgical systems used for patients requiring spinal surgeries that do not involve pedicle screw placement are lacking.
Joint occurrence of heatwaves and ozone pollution and increased health risks in Beijing, China: role of synoptic weather pattern and urbanization
Authors: Zong Lian , Yang Yuanjian , Xia Haiyun , Gao Meng , Sun Zhaobin , Zheng Zuofang , Li Xianxiang , Ning Guicai , Li Yubin , Lolli Simone
Published: May 2022

Abstract. Heatwaves (HWs) paired with higher ozone (O3)
concentration at the surface level pose a serious threat to human health. Their
combined modulation of synoptic patterns and urbanization remains unclear.
Using 5 years of summertime temperature and O3 concentration
observation in Beijing, this study explored potential drivers of compound
HWs and O3 pollution events and their public health effects. Three
favorable synoptic weather patterns were identified to dominate the
compound HWs and O3 pollution events. These weather patterns
contributing to enhance those conditions are characterized by sinking air
motion, low boundary layer height, and high temperatures. Under the
synergy of HWs and O3 pollution, the mortality risk from all
non-accidental causes increased by approximately 12.31 % (95 %
confidence interval: 4.66 %, 20.81 %). Urbanization caused a higher risk of HWs and O3 in urban areas than at rural stations. Particularly, due to
O3 depletion caused by NO titration at traffic and urban stations, the
health risks related to O3 pollution in different regions are
characterized as follows: suburban stations > urban stations
> rural stations > traffic stations. In general,
favorable synoptic patterns and urbanization enhanced the health risk of
these compound events in Beijing by 33.09 % and 18.95 %, respectively.
Our findings provide robust evidence and implications for forecasting
compound HWs and O3 pollution events and their health risks in
Beijing or in other urban areas all over the world that have high concentrations
of O3 and high-density populations.
Age spectra and other transport diagnostics in the North American monsoon UTLS from SEAC4RS in situ trace gas measurements
Authors: Ray Eric A. , Atlas Elliot L. , Schauffler Sue , Chelpon Sofia , Pan Laura , Bönisch Harald , Rosenlof Karen H.
Published: May 2022

Abstract. The upper troposphere and lower stratosphere (UTLS) region during the
summer monsoon season over North America (NAM) is influenced by the
transport of air from a variety of source regions over a wide range of timescales (hours to years). Age spectra are useful for characterizing the
transport into such a region, and in this study we use and build on recently
developed techniques to infer age spectra from trace gas measurements with
photochemical lifetimes from days to centuries. We show that the
measurements taken by the whole-air sampler instrument during the
SEAC4RS campaign can be used to derive not only age spectra, but also
path-integrated lifetimes of each of the trace gases and partitioning
between North American and tropical surface source origins. The method used
here can also clearly identify and adjust for measurement outliers that were
influenced by polluted surface source regions. The results are generally
consistent with expected transport features of the NAM but also provide a
range of transport diagnostics (age spectra, trace gas lifetimes and surface
source regions) that have not previously been computed solely from in situ
measurements. These methods may be applied to many other existing in situ
datasets, and the transport diagnostics can be compared with
chemistry–climate model transport in the UTLS.
An ensemble-variational inversion system for the estimation of ammonia emissions using CrIS satellite ammonia retrievals
Authors: Sitwell Michael , Shephard Mark W. , Rochon Yves , Cady-Pereira Karen , Dammers Enrico
Published: May 2022

Abstract. An ensemble-variational inversion system is developed for the estimation of ammonia emissions using ammonia retrievals from the Cross-track Infrared
Sounder (CrIS) for use in the Global Environmental Multiscale – Modelling Air quality and Chemistry (GEM-MACH) chemical weather model. A novel
hybrid method to compare logarithmic retrieval parameters to model profiles is presented. Inversions for the monthly mean ammonia emissions over
North America were performed for May to August 2016. Inversions using the hybrid comparison method increased ammonia emissions at most locations
within the model domain, with total monthly mean emissions increasing by 11 %–41 %. The use of these revised emissions in GEM-MACH reduced
biases with surface ammonia observations by as much as 25 %. The revised ammonia emissions also improved the forecasts of total (fine + coarse)
ammonium and nitrate, as well as ammonium wet deposition, with biases decreasing by as much as 13 %, but they did not improve the forecasts of just
the fine components of ammonium and nitrate. A comparison of biases resulting from inversions using different comparison methods shows favourable
results for the hybrid comparison method.
Climatic, weather, and socio-economic conditions corresponding to the mid-17th-century eruption cluster
Authors: Stoffel Markus , Corona Christophe , Ludlow Francis , Sigl Michael , Huhtamaa Heli , Garnier Emmanuel , Helama Samuli , Guillet Sébastien , Crampsie Arlene , Kleemann Katrin , Camenisch Chantal , McConnell Joseph , Gao Chaochao
Published: May 2022

Abstract. The mid-17th century is characterized by a cluster
of explosive volcanic eruptions in the 1630s and 1640s, climatic conditions
culminating in the Maunder Minimum, and political instability and
famine in regions of western and northern Europe as well as China and Japan. This contribution investigates the sources of the eruptions of the 1630s and 1640s and their possible impact on contemporary climate using ice core, tree-ring, and historical evidence but will also look into the
socio-political context in which they occurred and the human responses they
may have triggered. Three distinct sulfur peaks are found in the Greenland
ice core record in 1637, 1641–1642, and 1646. In Antarctica, only one
unambiguous sulfate spike is recorded, peaking in 1642. The resulting
bipolar sulfur peak in 1641–1642 can likely be ascribed to the eruption of
Mount Parker (6∘ N, Philippines) on 26 December 1640, but sulfate
emitted from Komaga-take (42∘ N, Japan) volcano on 31 July 1641
has potentially also contributed to the sulfate concentrations observed in
Greenland at this time. The smaller peaks in 1637 and 1646 can be
potentially attributed to the eruptions of Hekla (63∘ N, Iceland)
and Shiveluch (56∘ N, Russia), respectively. To date, however,
none of the candidate volcanoes for the mid-17th century sulfate peaks
have been confirmed with tephra preserved in ice cores. Tree-ring and
written sources point to cold conditions in the late 1630s and early 1640s
in various parts of Europe and to poor harvests. Yet the early 17th
century was also characterized by widespread warfare across Europe – and in particular the Thirty Years' War (1618–1648) – rendering any attribution of socio-economic crisis to volcanism challenging. In China and Japan, historical sources point to extreme droughts and famines starting in 1638 (China) and 1640 (Japan), thereby preceding the eruptions of Komaga-take (31 July 1640) and Mount Parker (4 January 1641). The case of the eruption
cluster between 1637 and 1646 and the climatic and societal conditions
recorded in its aftermath thus offer a textbook example of difficulties in
(i) unambiguously distinguishing volcanically induced cooling, wetting, or
drying from natural climate variability and (ii) attributing political
instability, harvest failure, and famines solely to volcanic climatic
impacts. This example shows that while the impacts of past volcanism must
always be studied within the contemporary socio-economic contexts, it is
also time to move past reductive framings and sometimes reactionary
oppositional stances in which climate (and environment more broadly) either
is or is not deemed an important contributor to major historical events.
Methane, carbon dioxide, hydrogen sulfide, and isotopic ratios of methane observations from the Permian Basin tower network
Authors: Monteiro Vanessa C. , Miles Natasha L. , Richardson Scott J. , Barkley Zachary , Haupt Bernd J. , Lyon David , Hmiel Benjamin , Davis Kenneth J.
Published: May 2022

Abstract. We describe the instrumentation, calibration, and uncertainty of the network of ground-based, in situ, cavity ring down spectroscopy (CRDS)
greenhouse gas (GHG) measurements deployed in the Permian Basin. The primary goal of the network is to be used in conjunction with atmospheric
transport modeling to determine methane emissions of the Delaware sub-basin of the Permian Basin oil and natural gas extraction area in Texas and
New Mexico. Four of the measurements are based on tall communications towers, while one is on a building on a mountain ridge, with the recent
addition of a small tower at that site. Although methane (CH4) is the primary species of interest, carbon dioxide (CO2), hydrogen
sulfide (H2S), and the isotopic ratio of methane (δ13CH4) are also reported for a subset of the sites. Measurements were
reported following the WMO X2004A scale for CH4 and the WMO X2019 scale for CO2. CRDS instruments were calibrated for CH4 and
CO2 in the laboratory prior to deployment. For H2S, data were offset-corrected using the minimum 40 min running mean value of the
day, and for δ13CH4, calibrations were based on laboratory data. We describe the characteristics of the dataset with a set of
illustrative analyses. Methane and carbon dioxide showed strong seasonality, with a well-defined diurnal cycle during the summer, which was opposed
to the winter, when a diurnal cycle was absent. CH4 enhancements to the background, during the winter, are up to twice the summer values,
which is attributed to the changes in boundary layer depth and wind speed. The largest CH4 enhancements occurred when winds blow from the
center of the Delaware sub-basin, where most of the methane emissions come from. The magnitude of enhancements of CO2 did not present
seasonality. H2S enhancements indicated a potential source northeast of the tower (Hobbs, New Mexico) where the inlet is installed. Isotopic
ratios of methane indicated that oil and natural gas extraction is the source of local methane in the region. The hourly-averaged data, starting on
1 March 2020 and described in this paper, are archived at The Pennsylvania State University Data Commons at https://doi.org/10.26208/98y5-t941 (Monteiro et
al., 2021).
Imatinib disassembles the regulatory core of Abelson kinase by binding to its ATP site and not by binding to its myristoyl pocket
Authors: Grzesiek Stephan , Paladini Johannes , Habazettl Judith , Sonti Rajesh
Published: May 2022

Abstract. It was recently reported (Xie et al., 2022) that the
Abelson tyrosine kinase (Abl) ATP-site inhibitor imatinib also binds to
Abl's myristoyl binding pocket, which is the target of allosteric Abl
inhibitors. This was based on a crystal structure of a truncated Abl kinase
domain construct in complex with imatinib bound to the allosteric site as
well as further isothermal titration calorimetry (ITC), NMR, and kinase activity data. Although imatinib's affinity for the allosteric site is significantly weaker (10 µM) than for the ATP site (10 nM), imatinib binding to the allosteric site may
disassemble the regulatory core of Abl, thereby stimulating kinase activity, in particular for Abl mutants with reduced imatinib ATP-site affinity. It was argued that the previously observed imatinib-induced opening of the Abl regulatory core (Skora et al., 2013; Sonti et al., 2018) may be caused by the binding of imatinib to
the allosteric site and not to the ATP site. We show here that this is not
the case but that indeed imatinib binding to the ATP site induces the
opening of the regulatory core at nanomolar concentrations. This agrees with findings that other type-II ATP-site inhibitors (nilotinib, ponatinib)
disassemble the regulatory core despite demonstrated negligible binding to
the allosteric site.
Spectral induced polarization imaging to investigate an ice-rich mountain permafrost site in Switzerland
Authors: Maierhofer Theresa , Hauck Christian , Hilbich Christin , Kemna Andreas , Flores-Orozco Adrián
Published: May 2022

Abstract. Spectral induced polarization (SIP) measurements were
collected at the Lapires talus slope, a long-term permafrost monitoring site
located in the western Swiss Alps, to assess the potential of the frequency
dependence (within the frequency range of 0.1–225 Hz) of the electrical
polarization response of frozen rocks for an improved permafrost
characterization. The aim of our investigation was to (a) find a field
protocol that provides SIP imaging data sets less affected by
electromagnetic coupling and easy to deploy in rough terrains, (b) cover the
spatial extent of the local permafrost distribution, and (c) evaluate the
potential of the spectral data to discriminate between different substrates
and spatial variations in the volumetric ice content within the talus slope.
To qualitatively assess data uncertainty, we analyse the misfit between
normal and reciprocal (N&R) measurements collected for all profiles and
frequencies. A comparison between different cable setups reveals the lowest
N&R misfits for coaxial cables and the possibility of collecting
high-quality SIP data in the range between 0.1–75 Hz. We observe an overall
smaller spatial extent of the ice-rich permafrost body compared to its
assumed distribution from previous studies. Our results further suggest that
SIP data help to improve the discrimination between ice-rich permafrost and
unfrozen bedrock in ambiguous cases based on their characteristic spectral
behaviour, with ice-rich areas showing a stronger polarization towards higher
frequencies in agreement with the well-known spectral response of ice.
Hybrid e-rehabilitation services: SMART-system for remote support of rehabilitation activities and services
Authors: Palagin Oleksandr V. , Malakhov Kyrylo S. , Velychko Vitalii Yu. , Semykopna Tetiana V.
Published: May 2022

One of the most effective solutions in medical rehabilitation assistance is remote patient / person-centered rehabilitation. Rehabilitation also needs effective methods for the “Physical therapist – Patient – Multidisciplinary team” system, including the statistical processing of large volumes of data. Therefore, along with the traditional means of rehabilitation, as part of the “Transdisciplinary intelligent information and analytical system for the rehabilitation processes support in a pandemic (TISP)” in this paper, we introduce and define: the basic concepts of the new hybrid e-rehabilitation notion and its fundamental foundations; the formalization concept of the new Smart-system for remote support of rehabilitation activities and services; and the methodological foundations for the use of services (UkrVectores and vHealth) of the remote Patient / Person-centered Smart-system. The software implementation of the services of the Smart-system has been developed.
La muralla y las primeras huellas de urbanismo de la fase ibérica antigua de La Alcudia de Elche
Authors: Uroz Rodríguez Héctor , Lorrio Alvarado Alberto J. , Uroz Sáez José
Published: May 2022

En este trabajo se presentan los resultados preliminares de las recientes excavaciones llevadas a cabo en el Sector 11D-E de La Alcudia, en el entorno directo de aparición de la Dama de Elche. El foco se pone en los hallazgos relativos a la fase ibérica más antigua, protagonizados por una muralla de cajones, con zócalo de piedra de una o dos hiladas y alzado de adobe. Esta, erigida sobre niveles estériles, se ha podido localizar en diversas catas en unos 55 m lineales. En la zona donde más se ha intervenido, se asocia a un incipiente urbanismo (LAI-1), cuyo registro ha permitido obtener dataciones absolutas del s. V a. C., con la detección de tres ambientes amortizados en época plena-final (LAI-2). A la funcionalidad estrictamente defensiva de la obra debe añadírsele su carácter emblemático y de prestigio, asociado a la condición de centro jerárquico del territorio meridional alicantino ejercida por Ilici desde fecha temprana, que explicaría el excepcional conjunto escultórico allí recuperado, entre el que se incluye la Dama como pieza más emblemática, y que posiblemente fue ocultada en un tramo de lo que hoy sabemos fue la muralla fundacional de La Alcudia ibérica.
Redes transnacionales de propaganda a favor de la Republica: Guillermo Fernández Zuñiga y la producción cinematográfica Spain in exile
Authors: López Martín Laura
Published: May 2022

Finalizada la Segunda Guerra Mundial, el gobierno de Giral puso en marcha una campaña de propaganda cinematográfica con el objetivo de obtener apoyos contra Franco y conseguir recursos para el socorro de los refugiados. La película de Guillermo Fernández Zuñiga, Spain in exile, permite analizar tanto el mensaje político como la necesidad humanitaria de los republicanos españoles exiliados en Francia.
Espacio doméstico y televisión en España. Usos y memoria cotidiana de la televisión de los noventa
Authors: Chicharro-Merayo Mar , Gil-Gascón Fátima
Published: May 2022

El presente trabajo reflexiona sobre los imaginarios en torno a televisión de los años noventa, momento en el que irrumpieron los operadores privados y se multiplicó la oferta en España. Se recupera el período utilizando el punto de vista del espectador. El material de análisis se ha obtenido a través de grupos de discusión y las entrevistas en profundidad realizadas para pulsar la memoria de esta etapa.
Se constata una relación ambivalente con aquella televisión. Se reconstruye un medio que se consumía grupalmente y que realizaba una intensa función de cohesión social. Pero también se identifican dinámicas (simplificación, sentimentalización, transgresión moral…) y valores (machismo, clasismo, conservadurismo…) en torno a las que los espectadores suelen articular una lectura de oposición.
Agitación en las calles. La violencia política en la Transición española a través del fotoperiodismo
Authors: Tranche Rafael R.
Published: May 2022

Durante la Transición española (1975-1982) un sector de la sociedad, integrado por movimientos ciudadanos, asociaciones vecinales y partidos de extrema izquierda, utilizará la calle como lugar de protesta y reivindicación de los derechos democráticos. La respuesta del Estado, todavía anclado en las estructuras franquistas, será la represión policial. Ante esta nueva realidad, el fotoperiodismo se convertirá en un testigo privilegiado que sabrá captar los acontecimientos con una clara conciencia de su trascendencia histórica. A ello contribuyeron tres circunstancias excepcionales: la aparición de nuevos diarios, una edad dorada de las revistas con contenido político-social y una nueva generación de reporteros gráficos.
El debate social sobre juegos de azar online y menores en España
Authors: García Ruiz Pablo , López Iván , Solé Moratilla María José
Published: May 2022

El debate sobre los riesgos asociados a los juegos de azar online y la protección a los usuarios más vulnerables ha traspasado el ámbito académico hasta llegar a otros ámbitos sociales y políticos. En este artículo estudiamos la percepción que los agentes sociales más relevantes tienen sobre la evolución probable y el impacto previsible, en el futuro próximo, de los juegos de azar online en los menores de edad. Para ello conducimos un estudio con base en entrevistas cualitativas a miembros de los principales agentes sociales conectados con los juegos de azar online: familias afectadas por el juego problemático, asociaciones de apoyo a jugadores problemáticos, profesionales de la salud, reguladores, partidos políticos, empresas operadoras y profesionales de la publicidad. Los resultados obtenidos permiten identificar las posiciones y discursos de los diversos actores sobre sus preocupaciones principales, los problemas que se avecinan, qué aspectos van a mejorar y que cambios resultan necesarios. La comparación entre discursos permite establecer como conclusión cuáles son los principales consensos y disensos entre agentes, así como las principales contradicciones internas y los dilemas a que se enfrentan en el contexto del actual debate social.
IMPLEMENTASI MANAJEMEN PEMASARAN JASA DI SMK TARUNA BHAKTI DEPOK
Authors: Fitriyanto Fitriyanto , Rahmi Shinta Marlina , La Ode Yusnimirat , Mutiah Tuty
Published: May 2022

Jasa pendidikan akan baik jika dilakukan dengan pengelolaan pemasaran profesional dan benar. Tujuan dari manajemen pemasaran pada jasa pendidikan untuk mememudahkan lembaga dalam memasarkan kepada mayarakat. Sehingga dapat mengetahui bagaimana implementasi strategi dalam manajemen pemasaran di Sekolah SMK Taruna Bhakti Depok. Dalam penelitian ini menggunakan metode kualitatif dengan mengumpulkan data dari kegiatan observasi lapangan, wawancara terhadap sumber yang relevan, dan pengambilan dokumentasi dari tempat penelitian. Pelaksanaan bauran pemasaran jasa pendidikan di Universitas Bina Sarana Informatika Cabang Pemuda antara lain: (1) Strategi produk; (2) Strategi Price; (3) Strategi Place (lokasi); (4) Strategi Promotion; (5) Strategi People; (6)Strategi Physical Evendece; dan (7) Strategi Process. Selain itu penelitian ini juga membahas tentang perkembangan pemasaran di Sekolah SMK Taruna Bhakti Depok dari tahun ketahun dan berbagai macam produk jasa pendidikan yang ditawarkan agar konsumen lebih tertarik untuk melihat secara langsung keunggulan dari Sekolah SMK Taruna Bhakti Depok ini.
Study of Detection of Left Atrial Enlargement by Echocardiography and ECG Correlation in Cardiac and Non-Cardiac Diseases
Authors: Naqvi Dr. Abbas , Shadani Dr. A. K. , Gupta Dr. Shubhangi
Published: May 2022

Evidences highlight the importance of enlarged left atrium (LA) as a barometer of diastolic burden. Detection of left atrial enlargement or its progression is frequently important in clinical medicine. It is well established that LAE has close relationship with atrial fibrillation, systemic thromboembolism events and heart failure4.
ECG assessment of left atrial enlargement is a non-invasive and universally available method12. ECG analysis for left atrial enlargement includes configuration, amplitude and duration of ‘P’ wave55. Echocardiographic LA dimension is the best non – invasive test of left atrial size25. This prospective study was carried out in Ramakrishna care hospital Raipur for 24 months to study the detection of left atrial enlargement by echocardiography with ECG correlation in cardiac and non-cardiac diseases. Rheumatic mitral and aortic valve disease was the most common cause of left atrial enlargement accounting for 26.67% in this study. Next in this order were atrial fibrillation 20%, Hypertension 18.33%, IHD 13.34%, isolated aortic valve diseases 10%, cardiomyopathies 05%. MVP and Thyrotoxicosis each accounting for 3.33%. Echo was simple, non invasive technique to detect LAE from mild to severe grade and help for therapeutic purpose, prevent complications. So, echo was found to be more specific in detection of LAE than ECG.

Keywords: LA-Left atrium, LV-Left ventricle, AF-Atrial fibrillation.
Медико-социальные риски COVID-обусловленной нормальности и понимание возможности их профилактики в условиях амбулаторного стоматологического приёма
Authors:   ФГБОУ ВО «Северный Государственный Медицинский Университет», Юшманова Татьяна Николаевна , Копытов Александр Александрович ,   Белгородский государственный национальный исследовательский университет, Оганесян Арман Аршакович ,   Белгородский государственный национальный исследовательский университет, Авхачева Наталья Алексеевна ,   Белгородский государственный национальный исследовательский университет, Степанова Юлия Сергеевна ,   Белгородский государственный национальный исследовательский университет
Published: May 2022

Развитие пандемии, форматируя правила жизни, устанавливает новую нормальность, проявляющуюся изменением требований к безопасности социального взаимодействия и организации стоматологического амбулаторного приёма. Население и государство не могут достоверным образом прогнозировать возникновение пандемий, их проявления, характер развития. По этой причине изменения нормальности являются следствием, направленным на снижение негативных последствий пандемии. Частота мутации вируса, повышение вирулентности, обуславливающие характер протекания пандемии COVID-19, приводят к мысли о целесообразности рассуждений о пессимистическом сценарии развития медико-социальных взаимодействий. В статье определено понимание эффективности профилактических мероприятий, снижающих вероятность заражения COVID-19 среди студентов-стоматологов, их родителей и практикующих врачей. Все опрошенные считают вакцинацию наиболее значимым профилактическим мероприятием, снижающим риск заражения в процессе социального взаимодействия и при оказании стоматологической помощи. Эффективность остальных профилактических мер, направленных на обеспечение безопасности амбулаторного стоматологического приёма, различным образом оценивается группами опрошенных.
Механизм воздействия молекулярного водорода в комплексном лечении ран мягких тканей и общей хирургической инфекции
Authors:   Воронежский государственный медицинский университет имени Н.Н. Бурденко, Андреев Александр Алексеевич , Лаптиёва Анастасия Юрьевна ,   Воронежский государственный медицинский университет имени Н.Н. Бурденко, Глухов Александр Анатольевич ,   Воронежский государственный медицинский университет имени Н.Н. Бурденко, Коняшин Даниил Александрович ,   Воронежский государственный медицинский университет имени Н.Н. Бурденко, Коновалов Павел Андреевич ,   Воронежский государственный медицинский университет имени Н.Н. Бурденко, Золотухин Владимир Олегович ,   Воронежский государственный медицинский университет имени Н.Н. Бурденко
Published: May 2022

Молекулярный водород (МВ) достаточно давно известен как инертный газ, однако о его полезных свойствах стало известно только в 2007 году, когда были получены сведения о его антиоксидантных возможностях. Эффекты Н2 позволяют использовать его при комплексном лечении ран мягких тканей. В этом обзоре обсуждаются основные биологические действия, а также механизмы действия МВ при нарушениях целостности тканевых структур и септических повреждений органов со стороны основных способностей водорода: противоапоптических, противовоспалительных, антиоксидантных и аутофагических. Подробно описываются способы транспортировки, дозировки Н2, а также их достоинства и недостатки в практической медицине. Рассмотрены перспективы развития его внедрения в самые различные области лечения и основные проблемы, на которые до сих пор нет ответа.
Plant signalling and stress
Authors: Jacobsen Amy , Jourquin Joris , Ma Yinxuan
Published: May 2022

Hosted by New Phytologist Advisor, [Andre Kessler](https://benitezalfonso.wordpress.com/), Centre for Plant Science, University of Leeds.

Featuring

- Amy Jacobsen, author of [Root growth responses to mechanical impedance are regulated by a network of ROS, ethylene and auxin signalling in Arabidopsis](https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.17180)

- Joris Jourquin, author of [Two phylogenetically unrelated peptide-receptor modules jointly regulate lateral root initiation via a partially shared signaling pathway in Arabidopsis thaliana](https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.17919)

- Yingxuan Ma, author of [FLA11 and FLA12 glycoproteins fine-tune stem secondary wall properties in response to mechanical stresses](https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.17898)