bluuebunny/crossref_metadata_2025 huggingface dataset:
CHI PHÍ Y TẾ TRONG ĐIỀU TRỊ BỆNH LAO PHỔI NỘI TRÚ CÓ BẢO HIỂM Y TẾ: NGHIÊN CỨU CẮT NGANG TẠI BỆNH VIỆN PHỔI VĨNH LONG NĂM 2023
Authors: Hoàng Đình Tiếng , Phạm Thị Tố Liên , Nguyễn Thị Linh Tuyền , Nguyễn Phục Hưng , Trương Minh Thùy , Nguyễn Thị Kim Hân , Nguyễn Trọng Duy Thức , Nguyễn Văn Đông
Published: May 2024

Đặt vấn đề: Tổng số người mắc bệnh lao trên thế giới ngày càng tăng, trong khi đó bệnh lao là một trong những bệnh dễ dẫn đến nguy cơ gây tử vong nhất. Việc điều trị bệnh lao tiêu tốn một khoản chi phí khá lớn, tạo ra gánh nặng kinh tế không chỉ của riêng bệnh nhân mà còn là của chung xã hội. Mục tiêu nghiên cứu: xác định chi phí trực tiếp y tế và các yếu tố liên quan trong điều trị lao phổi cho người bệnh nội trú có bảo hiểm y tế tại Bệnh viên Phổi Vĩnh Long năm 2023. Đối tượng và phương pháp nghiên cứu: nghiên cứu mô tả cắt ngang tiến hành trên 258 hồ sơ bệnh án và bảng kê chi phí khám chữa bệnh nội trú của bệnh nhân có bảo hiểm y tế tại Bệnh viên Phổi Vĩnh Long từ tháng 04/2023 đến tháng 03/2024. Kết quả: Tổng chi phí trực tiếp y tế là 1.546.941.435 VNĐ, trong đó BHYT thanh toán 85,3%, bệnh nhân chi trả 14,7%. Chi phí trực tiếp y tế trung bình trên một đợt điều trị là 5.995.897 VNĐ, trong đó chi phí thuốc chiếm tỷ lệ cao nhất với 47,5%. Các yếu tố bệnh nền, số lượng bệnh nền và số ngày điều trị có liên quan đến chi phí trực tiếp y tế (p<0,05). Kết luận: Nghiên cứu đóng góp thêm một phần vào tài liệu tham khảo về tổng quan chi phí điều trị của bệnh lao phổi, giúp các chuyên gia đưa ra những chính sách, quyết định phù hợp với tình hình thực tiễn; đồng thời vận động người dân tham gia BHYT để giảm bớt gánh nặng kinh tế trong việc điều trị bệnh.
Obnova mesta Kranj po požaru leta 1749
Authors: Kos Dušan
Published: May 2024

The author investigated the consequences of the fire that destroyed most of the town of Kranj in 1749. Based on numerous damage inventories and correspondence between the town authorities and regional and state offices, he determined the reasons for the disaster (lack of water in the town), the extent of the damage, life in the town during the reconstruction, and the plans and methods of rehabilitation over a period of twenty years. The state authorities only partially co-financed the renovation with financial grants and limited tax exemptions. The townspeople bore the majority of the burden, which is why the revitalisation of Kranj took a long time. Mainly due to the lack of money and despite the ambitious initial ideas, the town, which was already in debt, was not notably urbanised or improved in terms of fire prevention compared to the Middle Ages. Some of the more notable changes in Kranj did not take place until the aftermath of another disastrous fire in 1811.
Inclisiran (Leqvio)
Authors: CADTH
Published: May 2024

CADTH recommends that Leqvio not be reimbursed by public drug plans as an adjunct to lifestyle changes, including diet, to further reduce low-density lipoprotein cholesterol (LDL-C) levels in adults who are on a maximally tolerated dose (MTD) of a statin, with or without other LDL-C–lowering therapies, and who have nonfamilial hypercholesterolemia (nFH) with atherosclerotic cardiovascular disease (ASCVD).
Evidence from 2 clinical trials showed that treatment with Leqvio lowered bad cholesterol (LDL-C) in adults with nFH with ASCVD who were already being treated with the highest possible dose of statins and in those who cannot tolerate treatment with statins.
A post hoc pooled analysis of major adverse cardiovascular events (MACEs) from the ORION-10 and ORION-11 trials precluded the Canadian Drug Expert Committee (CDEC) from determining whether inclisiran reduces the risk of cardiovascular morbidity and death in adults with nFH with ASCVD.
Patients identified a need for treatments that are less burdensome, can reduce bad cholesterol (LDL-C) and cardiovascular morbidity and death, and improve health-related quality of life (HRQoL); however, there was not enough evidence to show that Leqvio would reduce cardiovascular morbidity and death or improve HRQoL.
Representation of women and work in the most popular series in the UK and Spain
Authors: García-Muñoz Núria , Navarro-Bosch Celina , Delgado-Reina Matilde
Published: May 2024

This study provides a portrait of the occupational roles in the series most watched on the generalist DTT channels in the United Kingdom and Spain. The media representations of gender role attitudes in the workplace, especially in fiction, influence the popular culture and social imaginary of the audiences. In this context, the study of the series with the largest audience is important to discover the patterns that these fictions show about work environments. This article analyzes 40 popular series broadcasts on generalist television channels in the United Kingdom and Spain. A sample of more than 400 characters reveals the representation of women and men in the workplace, highlighting the similarities and differences regarding job profiles, leadership, and prestige. The comparison between both markets allows us to find relevant concepts on the current representation of women and work. While in the UK the differences are minor, the results in Spain confirm the differences between male and female characters associated with various aspects of the workplace such as the prestige and positioning of the most qualified jobs.
Producción de conocimiento digital en el ámbito educativo del IPN desde la perspectiva de género
Authors: Ochoa Ayala Silvia
Published: May 2024

Introducción. En el devenir histórico de la tecnología, el papel de sus productoras/es ha ocupado lugares jerárquicos, la producción androcéntrica ha privilegiado ciertas formas de crear y de producir los saberes tecnológicos invisibilizando la riqueza que poseen las diferentes formas de abordarla. Objetivo. En este estudio, se buscó identificar la forma en que las jóvenes politécnicas producen conocimiento desde el ámbito digital, entendiendo lo digital como un ámbito de producción tecnocientífica que se encuentra articulado con la forma de legitimar la producción científica: la androcéntrica. Metodología. Se entrevistó a 10 jóvenes cuyas edades fluctúan entre los 20 y 24 años, reciben su formación académica en la Escuela Superior de Sistemas Computacionales del Instituto Politécnico Nacional, Ciudad de México (Ingeniería en Sistemas Computacionales). A través de la narración de sus experiencias durante la vida estudiantil, se construyeron 6 categorías de análisis: a) Experiencia durante el bachillerato, b) Transición del bachillerato al nivel superior, c) Vínculo con las y los docentes, d) Ambiente escolar y relación con los pares, e) Violencia epistémica y f) Acoso. Resultados. Se identificó que las jóvenes reciben un elevado grado de violencia epistémica a lo largo de su formación que inicia en el nivel bachillerato, teniendo continuidad en el espacio de formación superior, siendo uno de los indicadores el reducido número de mujeres que cursan estas carreras, además de la expresión de maltrato que las jóvenes relatan. Por otra parte, también se expresaron diferencias didácticas y una significativa distancia emocional en la relación entre pares.  Conclusiones. Se hace necesario desnaturalizar la violencia ejercida hacia las mujeres en este ámbito de formación digital, así como relevar otras formas de producir conocimiento desde la sensorialidad, desde la creatividad, desde la empatía con las necesidades sociales situadas y desde un tiempo pertinente para la formación estudiantil.
Sanna Marin y una nueva forma de hacer comunicación política a través de Instagram
Authors: González Grimón Sima , Brito Lorenzo Diego
Published: May 2024

Resumen: Introducción y objetivos. Este artículo explora la red social de Instagram de Sanna Marin como medio de comunicación política desde su llegada al gobierno en diciembre de 2019 hasta el 1 de septiembre de 2022. El propósito de esta investigación es analizar la comunicación que utiliza Sanna Marin en la red social Instagram, y por lo tanto, conocer el modo en que emplea esta herramienta de comunicación política para conectar con su audiencia y qué tipo de contenidos proyecta en las publicaciones. Metodología. A través de la revisión bibliográfica se elabora una ficha de análisis de contenido en la que se analizan un total de 381 publicaciones y 932 elementos audiovisuales. Resultados. Sanna Marin es la protagonista en el 94,94% de los elementos audiovisuales, en los que los símbolos de identidad del partido no tienen una fuerte presencia con un 9,46%. La fotografía estándar destaca por encima de vídeos, selfies o portadas de revista, junto al ul uso del color es predominante frente al blanco y negro. La indumentaria intercala la formalidad e informalidad, con un tono informativo y cercano en las publicaciones. Conclusiones. Sanna Marin no utiliza un tipo de estrategia comunicativa determinada en la red social Instagram, ya que alterna publicaciones de tipo privado y de la actividad política diaria. Además, utiliza un lenguaje cercano para poder conectar con su público, acercar la vida política a la ciudadanía y humanizarla.
Geo-Jute for River Bank Protection - A Case Study
Authors: S. K. Ghosh  , R.K. Ganguly  , S. Debnath  , D. Nag
Published: May 2024

Geo-jute is jute matting, which has been successfully developed by needle-punched non-woven and woven techniques and has been tried for erosion control and reinforcement of soil. Plant roots trap soil particles and prevent erosion. Non-woven & Woven Jute Geo-fabrics are widely used, as these are eco-friendly, economical, biodegradable, nontoxic, non-plastic, hydrophytes, made of messy fibres and are good for draping. Jute degrades quickly and produces ligno-mass in the soil with additional nitrogen, phosphorus and potassium. Thus the fertility and texture of soil are improved. In the present field trials, NIRJAFT experimented Non-Woven and Woven Jute Geo-textiles for control of soil erosion on moderate slopes (300 - 15°) as well as dense fabrics (two-fold) for separation and filtration for the protection of the bank of river Hooghly in West Bengal.
Effect of Storage on Quality of Stone Apple Ready-to-Serve Beverage
Authors: Kalpana Rayaguru  , Md. K. Khan  , N R Sahoo
Published: May 2024

The present study is an effort to explore the possibility of effective utilization of the raw stone apple (Aegle marmelos correa), an indigenous fruit rich in nutritional as well as medicinal qualities. As the keeping quality of the whole fruit is very less, improvement in the post harvest processing and other relevant aspects need to be studied. Value added nutraceutical ready-to-serve (RTS) have been prepared. The process parameters have been standardized with respect to biochemical, microbial and sensory acceptance. Storage experiments for RTS with treatments (control, preservative and ginger) were conducted for 8 months and quality analysis was carried out to assess the storability. The ready to serve beverage with 13% pulp, 14Brix and 0.3% acidity was considered standard based on organoleptic evaluation. The RTS blended with ginger juice fetched higher sensory acceptability. Five hundred numbers of bottles of RTS of 200 ml. capacity each could be prepared from 25 kg of stone apple. During storage of the beverage all the biochemical qualities changed with storage period irrespective ofthe treatments. The total sugar, pH and ascorbic acid ofthe RTS got reduced with storage period where as an increasing trend was observed in acidity and TSS. However, the changes were maximum in control samples. The results suggest the use of ginger juice as a source of natural preservative. After four months of storage, there was an indication of presence of total mould count and total bacterial count in the stored samples, but the population was well within the safe limits till the end of a storage period of eight months.
A rare clinical image: Papillomatosis cutis lymphostatica in a black patient
Authors:   Medical College of Georgia, Augusta, Georgia, USA., Beller Sarah
Published: May 2024

Patient is a 53 year-old black woman with a history of type 2 DM, HTN, R knee total arthroplasty, and significant obesity. She has been suffering with chronic lymphedema for several years and is presenting today with papillomatosis cutis lymphostatica with overlying cellulitis to the right lower extremity (Figures 1,2). Supporting clinical features in this patient include common features such as shiny, smooth, pearl-like, hyperkeratotic papules that are either flesh toned or hyperpigmented, positive stemmer sign, and hyperkeratotic hyperpigmented skin [1]. At this stage of pathology, edema is no longer pitting in nature. Papules range in size from 0.5 to 1 cm and are predominantly dome-shaped or occasionally scalloped (Figure 3). Today, She did have overlying erythema and discomfort upon exam due to the concurrent cellulitis, but does not typically experience pain related to the lesions. Risk factors for this patient include history of poorly controlled type [2] diabetes mellitus, right total knee replacement and varicose veins in bilateral lower extremities [1].
Cutaneous squamous cell carcinoma with osteoclast-like giant cells in an 87-year-old male
Authors:   DO 4743 Oyster Reef Run, Wilmington, NC82405, USA., Geist Ryan
Published: May 2024

Cutaneous Squamous Cell Carcinoma (SCC) with Osteoclast-Like Giant Cells (OLGCs) is a rare finding, with only 11 previous cases reported in the literature. The origin of the OLGC within carcinomas has been debated, and there are two prevailing theories regarding the cell origin. We report the 12th case of SCC with OLGCs, discuss the two theories, and analyze the common features among all twelve cases. Ultimately, there appears to be an association between OLGCs and poorly differentiated cutaneous squamous cell carcinomas. Consequently, OLGCs should lead to an increased index of suspicion, as they may be a predictor of poor outcomes. If OLGCs are identified on histology, the pathologist should consider the addition of Preferentially-expressed Antigen in Melanoma (PRAME) immunostaining as a means of more accurately determining the prognosis. In conjunction with clinical features, histology should guide clinical recommendations and may warrant chemoprevention with systemic retinoids in high-risk individuals.
Davener’s dermatosis: A case report
Authors:   Senior Consultant Dermatovenereologist, Department of Skin, STDs and Leprosy, KMCH Speciality Hospital, Erode, Tamilnadu, India., Rajagopalan Rajesh
Published: May 2024

Davener’s dermatosis is a variant of frictional hyperpigmentation first reported in 2000. It appears clinically as an elongated, vertical, midline, hyper pigmented patch with ill-defined borders, distributed along the skin over bony prominences of inferior thoracic and lumbar vertebrae. Histopathology revealed diffuse hyperkeratosis and hyperplastic epidermis with diffuse basal hypermelanosis. We report a case of Davener’s dermatosis in a male student, though common which is not widely reported in literature which was treated with 1064-nm Q-switched Nd: YAG laser with low fluence with partial improvement.
Colonic perforation caused by secondary systemic amyloidos
Authors:   Department of Gastroenterology, Mohamed Taher Maamouri Hospital, Nabeul, Tunisia., khsiba Amal
Published: May 2024

Amyloidosis is a rare condition characterized by the accumulation of amyloids in various tissues. These amyloid proteins are usually misfolded and form insoluble fibrils that deposit in the extracellular spaces of tissues, disrupting their normal structure and function. Amyloidosis can either be acquired or hereditary, systemic or localized.
SPECIAL ISSUE: Male-Female Differences in Psychophysiological Stress Profiles Before and After a Group Relaxation/Biofeedback Stress Management Program
Authors: Wilson Vietta , Somers Kathy , Peper Erik
Published: May 2024

This study used stress profiles to assess whether a biofeedback-assisted stress management program that previously documented decreased anxiety, stress symptoms, medication use, and increased well-being also had physiological effects. Psychophysiological stress profiles are used in quantifying an individual’s responses under stress and during recovery from stressors by looking at their degree of response, pattern of response, and degree of recovery. A stress profile measuring surface electromyography (sEMG), heart rate, and skin temperature was performed on 141 adults before and after their participation in a group relaxation and stress management program. After 10 sessions of skills training, the only significant change in physical parameters was warmer hand temperatures in both males and females. Temperature was also the only modality that was included as biofeedback training within the program. Trait anxiety (STAI) was significantly positively correlated with females’ sEMG before and after the program. Females had significantly colder hands, higher heart rate, and a pattern of higher sEMG than males did throughout all profiles. The responses and recovery from different stressors showed some significant male-female differences. Future psychophysiological and psychological studies should further investigate male-female differences.
Finding synergies between agroecology and industrial ecology toward sustainable agricultural systems
Authors: Costello Christine
Published: May 2024

The question of how humans will co-create better food and agricultural systems is ex­tremely complex, and responses vary significantly due to experiences, worldviews, and values. Those of us working on this question typically agree that the goal is to realize systems that are equitable, just, minimize harm to, and ultimately support healthy ecosystems for current and future generations. I will refer to this goal as sustainability. My training is in industrial ecology and civil and environmental engineering, and my professional research focuses on questions of the climate and nutrient impacts associated with agriculture and food products as they are in our time, i.e., dominated by commodity crops. I was introduced to agroecology about 15 years ago while looking into ways to reduce nutri­ent runoff and improve soil and ecosystems, such as alternative cropping systems, integrated farming practices, permaculture, and more. Eventually, I learned of agroecology as a science, movement, and practice, which increased my interest to learn more. Both industrial ecology and agroecology, and the many branches within them, earnestly pursue facets of sustainability in agriculture, food, and other bio-based systems, and collaboration could lead to synergistic efforts. . . .
Enantiomorphs no more: Indigenous agroecology and the future of food sovereignty: Reflections on the U.S. United States Agroecology Summit 2023
Authors: Peña Devon
Published: May 2024

I was part of a plenary panel on “Bridge Build­ers” at the 2023 Colorado Food Summit in Denver in December 2023. Echoing a statement I first made at the U.S. Agroecology Summit 2023, I explained how the first “bridge” we are building at The Acequia Institute (TAI) is between Indigenous Knowledge (IK) and so-called Western Science (WS). TAI does this work not to verify and legiti­mize IK by invoking the presumably more rigorous and mathematical methods and materials of WS. TAI enunciates and practices IK through autono­mous place-based food sovereignty initiatives. In this work we have determined how best to inte­grate the methods and materials of selected domains of Western knowledge systems in forms useful for us and the locality. These issues were discussed at the U.S. Agroecology Summit, but in the end they were left largely unresolved. The entire Summit was, as Carmen Cortez and others have rightly observed, plagued by being “Devoid of this spirit of place and people…” (Agroecology Summit ‘Outside Empire’ Subgroup, 2024, p. 2). In my view, it was a gathering fractured by pre-existing and possibly inadvertent and unconscious acts of epistemic violence reminding me of the difference Michael Redclift (1987) observed between top-down environmental managerialism and bottom-up collaborative environmental management. . . .
光與暗的整合：社會正義取向諮商心理師專業耗竭經驗及調適歷程之探究
Authors: 林郁嘉 林郁嘉 , 張曉佩 張曉佩
Published: May 2024

社會正義取向的諮商模式是以改善個案受到的壓迫狀態為目標，過程往往需投入許多心力，因此諮商心理師容易處於專業耗竭的狀態，調適專業耗竭成為諮商心理師必經的挑戰。本研究的目的在探討社會正義取向的諮商心理師其專業耗竭經驗、因應專業耗竭的策略以及因應專業耗竭的調適歷程。本研究邀請三位採社會正義取向的諮商心理師參與研究，以敘說研究法作為研究方法，並以多元文化諮商與社會正義諮商的觀點來論述研究參與者進行倡導的經驗樣態，研究結果分為三部分，第一部分為「社會正義取向之諮商心理師的專業耗竭經驗」包含：1.社會倡導的連續性工作，增加專業耗竭發生頻率；2.無極限的倡導工作，瀕臨極限的倡導者。研究結果第二部分為「社會正義取向之諮商心理師的專業耗竭調適策略」包含：1.多元觀點的理解與行動是渡過「無力無望感」的利器；2.接納自身限制，找回意義感的自我照顧。研究結果第三部分為「社會正義取向之諮商心理師的專業耗竭調適歷程」包含：1.覺察專業耗竭的發生；2.暫停/減少倡導工作；3.自我反思/沉澱時期；4.整理專業耗竭中的好與不好經驗；5.重新找到新的倡導信念；6.繼續開展倡導工作。
The social justice approach counseling aims to improve the oppressive state of the client, and the process requires a lot of effort. Therefore, counseling psychologists are prone to burnout, and adjusting burnout has become an inevitable challenge for counseling psychologists. The purpose of this study was to explore the experience of burnout, the strategies and the adjustment process of coping with burnout among counseling psychologists with the social justice approach. This study invited three counseling psychologists as research participants and adopted the narrative research method. This study revealed the advocacy experience from multicultural counseling and social justice counseling perspectives. The research outcomes of the burnout experience of the participants were as follows: (1) The continuous work of social advocacy increases the frequency of professional burnout. (2) Unlimited advocacy work and advocates who are on the verge of limits. The coping strategies were as follows: (1) The understanding and action of multiple perspectives is a sharp tool to overcome the "powerlessness and hopelessness"; (2) Accepting one’s limit and finding meaning in self-care. In addition, the adjustment processes of the participants were as follows: (1) Be aware of professional burnout; (2) Pause/reduce advocacy works; (3) Self-reflection/thinking period; (4) Sort out good and bad experiences in professional burnout; (5) Find the new advocacy beliefs; (6) Restart advocacy work.

 
Forms of Translation, Translation of Forms: From Gorky’s Mother to Mahasweta Devi’s Mother of 1084
Authors: Banerjee Sandeep
Published: May 2024

This article focuses on the Bengali novel হাজার চুরাশির মা (Mother of 1084) by Mahasweta Devi to read it as a rewriting of Maxim Gorky’s The Mother. It contends that Mother of 1084 recasts Gorky’s radical and gendered bildungsroman for the context of India where it not only documents the development of the radical consciousness of Sujata, the mother of the revolutionary Brati killed by the Indian state, but also the patriarchal structure of the Indian/Bengali family. Furthermore, it argues that the Bengali novel recasts the socialist realism of the Russian novel into modernist Bengali prose. It examines Mahasweta’s deployment of the modernist aesthetic while locating Mother of 1084 in a broader tradition of actually existing communist artistic praxis in South Asia to illuminate the tradition of committed modernism.
Effect of Smoking on Survival in patients with Squamous Cell Carcinoma of Oral Cavity
Authors: Khan Khadeeja , Ghafoor Javeria , Immran Muhammad , Aslam Muhammad Faisal , Ishaque Nimrah , Saleem Ashja , Rana Maheen
Published: May 2024

Background: Oral squamous cell carcinoma (OSCC) is a growing disease affecting older men and those without risk factors. It's also increasing in younger individuals. Understanding the disease's evolving patterns and risk factors is crucial for effective management. Tobacco is the primary cause, contributing to 95% of OSCC. New prevention and treatment approaches are possible with genetic markers and environmental triggers. Study Design: A cross-sectional study Place of Study: Chughtai Institute of Pathology, Lahore Study Duration: January 2022 to May 2023 Methodology: A study involving 46 patients with oral squamous cell carcinoma (OSCC) found that tobacco use significantly impacts the long-term prognoses and treatment. The patients underwent extensive surgery and received personalized adjuvant treatment. The study aimed to evaluate the impact of multimodal therapy on patient survival and quality of life. Result: The patient also exhibited the table's traits. Most patients were male. The tongue was the most affected with 26 instances (65%), whereas the buccal mucosa had 10 cases (25%) Floor of mouth (10%). It is highly probable that the mouth was involved. 24% of patients had PT1, 35% had pT2, 11% had pT3, etc. 56% of patients had pathogenic nodal stage pN0, 15% had pN1, 27% had pN2, and 2% had pN3. The median depth of invasion was 10 millimetres, with the smallest margin being six. Conclusion: The research also categorized patients based on age and tobacco consumption, revealing that smokers experience distinct psychological and functional effects. The findings could help tailor OSCC treatment to tobacco-consuming countries like Pakistan. Keywords: Squamous cell carcinoma, survival, Oral cancer, tobacco
A Randomized Controlled Trial Comparing Injection Polidocanol, with Injection 50% D/W in Rectal Prolapse
Authors: Siddiqi Umair Khaliq , Sharif Muhammad , Adnan Hafiz Muhammad , Rafiq Hafiza Mariam , Bashir Muhammad Kashif , Malik Hamza
Published: May 2024

Background: Rectal prolapse manifests as the protrusion of the rectal mucosa through the anal opening. There can be partial or full thickness prolapse. It usually occurs before 4 years of age. Rectal prolapse in childhood tends to affect both males and females equally. Aim: To compare Inj. Polidocanol with Inj 50% D/W in rectal prolapsed in this randomized controlled trial. Methods: The study was conducted in the pediatric surgical ward of Mayo Hospital & King Edward Medical University Lahore, after receiving approval from the Hospital's Ethical Committee. There were 60 patients rectal prolapse with 30 patients in each group. Polidocanol was used in group A while 50%dextrose water was used in group B. The procedure was performed under general anesthesia. In the postoperative period children were observed for early complications like fever, anaphylaxis, diarrhea, hemorrhage, pain while defecating, mucosal edema and constipation. Results were analyzed with SPSS. Results: Out of 60, 36 were male while 24 were female. Group A included 16 male and 14 females whereas group B had 20 males and 10 female children. Mean age was 5.35years with SD of 2.7 and ranging from youngest child of 8 months till eldest of 12 years. In group A mean age was 5.44 while mean age of group B was 5.26 years. All 30 patients in group A were relieved of their symptoms after single session of Polidocanol so giving 100% of success rate while 28 patients (93.33%) in group B were relieved of their symptoms while 2(6.66%) patients developed recurrence with no significant difference. The complications observed in the study were post-operative constipation in 3(10%) patients in group A, however no patient developed postoperative stricture, infection or adverse drug reaction. In group B no patient developed any post-operative complication. Practical Implication: This comparative study helps us to find more effective and better drug available as a sclerosing agent to treat rectal prolapse in pediatric population. It’s also cost effective and with fewer side effects and easily available. Conclusion: In conclusion, injection sclerotherapy using polidocanol emerges as an equally successful procedure for managing RP in children. This medication demonstrates enhanced efficacy, safety, and accessibility. The process is not only less time-consuming but also entails minimal complications. Keywords: Rectal Prolapse Manifests, Protrusion, Mucosa, Chronic Constipation, Hirschsprung’s Disease,
Translation and Validation of Leicester Cough Questionnaire for Cystic Fibrosis Patients
Authors: Khan Hadia , Waqas Shoaib , Tariq Muhammad , Niamat Atiqa , Asim Hafiz Muhammad , Saeem Zeeshan
Published: May 2024

Aim: To translate and validate Leicester cough questionnaire in Urdu language for patients with Cystic fibrosis. Methods: It is a cross-cultural linguistic study. 150 participants were included in the study and Non probability convenient sampling was used. Inclusion criteria includes parents of children with CF, who understand Urdu, and have symptoms of chronic cough. Children with severe respiratory exacerbations were excluded. Data was entered using SPSS version 25 and same software was used for data analysis. Results: It took 6 months to achieve an Urdu version of LCQ, which proved to be satisfactorily acceptable when administered to 150 subjects. The questionnaire showed acceptable internal consistency (Cronbach’s alpha =0.916), test-retest reliability by Pearson correlation ranged from 0.203 to 0.99 and intraclass correlation coefficient value 0.2 to 0.9 showed high reliability. Conclusion: Leicester Cough Questionnaire is a valid and reliable tool for assessing the impact of cough on quality of life in patients with Cystic fibrosis. Keywords: Cystic fibrosis, Cough, Health related quality of life, Leicester cough questionnaire.
Effectiveness of Dapagliflozin in Reducing Incidence of Worsening Heart Failure Events among patients with Reduced Ejection Fraction
Authors: Asif Mohammad , Laique Talha
Published: May 2024

Background: Sodium–glucose co-transporter 2 (SGLT2) inhibitors are the groups of oral hypoglycemics that decreases the worse events among cardiac patients of chronic heart failure. Aim: To assess the effectiveness of Dapagliflozin in reducing the incidence of worsening heart failure events among chronic heart failure patients. Study design: Randomized controlled trial. Methodology: This study enrolled 480 cardiac patients with mildly reduced ejection fraction. This study was held at Punjab Institute of Cardiology. All patients received dapagliflozin 10mg once daily or matching placebo, in addition to usual therapy for four weeks. The data was entered and analyzed in SPSS 25. Independent sample t-test was used to compare the mean age and body mass index between two groups. Chi square test was used to compare gender and hypertension with primary composite. Results: There were 138(57.5%) males in Dapagliflozin group and 131(54.6%) males in placebo group. Dapagliflozin demonstrated significant benefits compared to placebo, as evidenced by lower rates of the primary composite outcome (15.8% vs. 23.3%, p = 0.038), hospitalization for heart failure or an urgent visit (10.4% vs. 20.0%, p = 0.003). Practical Implication: Chronic heart failure with mildly reduced ejection fraction is a major problem in modern era. Present study will highlight the effect of oral hypoglycemic, dapagliflozin, in reducing worse cardiovascular events among chronic heart failure patients. As there is a lack of local literature review on this health issue so this study added information to existing literature and add new dimensions in its treatment. Conclusion: It was concluded that dapagliflozin reduced worsening of cardiac events among heart failure patients with mildly reduced ejection fraction thus this drug is effective treatment option among cardiac failure patients in reducing hospitalization. Keywords: Heart Failure, Reduced Ejection Fraction, Effectiveness, Urgent Visits and Hospitalization
Comparison of Task-Oriented and Bobath-Based Trunk Training on Balance, Functional abilities and Walking in Ischemic Stroke Patients
Authors: Younas Fatima , Shafiq Hira , Khan Sara , Saleem Saweera , Mehmood Azhar , Ikram Adnan
Published: May 2024

Aim: To determine the outcome of task oriented and bobath based trunk training on balance in ischemic stroke patients Study design: Randomized controlled trial Place and duration: Physical Therapy department, Younas health care Hospital Shahdara Methodology: Sixty-six patients rewarding the inclusion and exclusion criteria were assigned in two groups, Group 1 and Group 2. Group 1 was given conventional treatment + Task oriented trunk and Group 2 was given receive Convention treatment + Bobath based trunk training. Participants in both groups were joined in a 12-week physiotherapy session that seen three days a weekly for one sixty minute respectively day. They stayed examined at starting point and after the 12-week mark. Berg Balance Scale and Trunk impairment scale were used as outcome measures. Results: The adjustment score of BBS was 8.93 (6.32-11.54) that helps in investigational set (P<0.001). Furthermore, variation score of the Trunk Impairment Scale between the groups was 3.34 (1.48-4.91). It also helps the Task-oriented group with (P<0.001). However, task-oriented approach is more effective. Conclusion: Exercises performed with task-oriented approach are more effective to improve balance and functions of the patients with ischemic stroke as associated to patients who were treated with Bobath approach. Besides, better improvement has been found on purposeful balance suggesting the surplus effects with task-oriented exercise. Keywords: Stroke, Bobath, Task-oriented, Balance
Antimicrobial Susceptibility Patterns of Salmonella Typhi and Salmonella Paratyphi in Tertiary Care Hospitals
Authors: Shah Muhammad Waqas , Ali Izhar , Zaman Ronaq , Din Fakhrud- , Hayat Tahir , Ullah Sami , Khan Ikram Ullah
Published: May 2024

Background: Salmonella typhi and Salmonella paratyphi are significant causes of enteric fever, posing substantial public health challenges globally. Monitoring their antimicrobial susceptibility patterns is crucial for guiding treatment strategies and combating antimicrobial resistance, particularly in tertiary care hospitals where severe cases are managed. Aim: To determine the antibiogram profile of Salmonella typhi and Salmonella paratyphi isolated from blood cultures of paediatrics patients presenting in Lady Reading Hospital Peshawar. Methodology: The study examined the prevalence, clinical characteristics, and antibiotic susceptibility patterns of Salmonella typhi and Salmonella paratyphi infections among 530 participants aged 13 to 18 years presenting in Lady Reading Hospital Peshawar. Over the course of two years using a prospective observational cohort design. Recruitment, clinical evaluations, and laboratory validation using accepted methods were all part of the data gathering process. Testing for antibiotic susceptibility was done, and statistical analysis was done using SPSS version 28. Both informed consent and ethical approval were obtained. Results: The research included 530 instances of enteric fever, of which 318 cases (or 60%) were due to Salmonella typhi and 212 cases (or 40%) to Salmonella Paratyphi. There were 40.25% female cases and 59.75% male cases among them. The age group of 15–16 years old accounted for the largest percentage of cases (38.68%), followed by 13–14 years old (33.02%) and 17–18 years old (28.30%). Different patterns emerged from antimicrobial susceptibility tests; drugs such as ampicillin (66.04%), azithromycin (74.26%), cefixime (87.47%), ceftriaxone (92.77%), chloramphenicol (91.51%), ciprofloxacin (92.40%), and co-trimoxazole (55.03%) showed substantial susceptibility rates. Compared to Salmonella typhi, Salmonella paratyphi showed notably greater sensitivity rates for azithromycin (94.47%) and ceftriaxone (95.45%). Practical implication: This research provided the community with important advantages and practical consequences. The study helps healthcare professionals choose efficient treatment plans by identifying the antibiotic susceptibility patterns of Salmonella typhi and Salmonella paratyphi, particularly in tertiary care facilities. Conclusion: This study highlights the importance of continuous surveillance and species-specific treatment strategies to combat antimicrobial resistance and improve patient outcomes in enteric fever, particularly in tertiary care settings. Keywords:Antimicrobial susceptibility, Salmonella typhi, Salmonella Paratyphi, Tertiary care hospitals
Navigating the Twisted Path of Delusional Disorder: A Patient Case Study
Authors: Waseem Ans , Butt Mirrat Gul
Published: May 2024

Background: Delusional disorder of the jealous type is a rare psychiatric condition characterized by persistent and unfounded beliefs that impair functionality and compromise relationships. This case study explores the presentation, management, and potential treatment outcomes for a patient experiencing an acute episode of Delusional Disorder. Aim: To assess the effectiveness of Cognitive behavioural Therapy in modifying delusional beliefs. Method: Cognitive behavioural therapy using psychoeducation, activity scheduling, trigger management, evidence gathering, reality testing, behavioural experiments, reasoning skills, 3C's, and verbal challenges. Results: The findings suggest that CBT techniques may be beneficial in managing Delusional Disorder, particularly the jealous type. This is evidenced by the significant improvement observed in the patient. Implications: Unawareness of Delusional Disorder can lead to misinterpretations as domestic disputes, delaying crucial interventions. Early diagnosis and treatment can help control symptoms and potentially prevent dangerous actions by the patient. Conclusion: The patient's significant improvement suggests that CBT may be a valuable tool for addressing delusional beliefs and associated disruptions. This finding highlights the need for further research to explore the broader applicability of CBT in treating various presentations of Delusional Disorder. Keywords: Delusional disorder, cognitive behavioural therapy, jealous paranoia.
PHARMACOLOGICAL EVALUATION OF COMMERCIALLY AVAILABLE POLYHERBAL FORMULATIONS FOR HEPATOPROTECTIVE AND ANTIOXIDANT ACTIVITIES
Authors:   Dept. of Pharmacognosy, Institute of Pharmaceutical Education and Research, Borgaon (Meghe), Wardha - 442 001, Maharashtra, India, Ganjiwale Rajendra O. , Yeole Pramod G. ,   Dr. Babasaheb Ambedkar Marathwada University, Aurangabad – 431 004, Maharashtra, India, Singhavi Dilesh J. ,   Dept. of Pharmaceutics, Institute of Pharmaceutical Education and Research, Borgaon (Meghe), Wardha - 442 001, Maharashtra, India
Published: May 2024

Polyherbal formulations, are frequently used to treat liver dysfunction, preserve the liver, and regenerate the liver. This research was carried out to determine whether or not polyherbal formulations could protect the livers of mice exposed to carbon tetrachloride -induced hepatotoxicity. 13 groups (n = 6) were generated at random from 78 male albino rats: Group I (serving as the normal control), Group II (containing only carbon tetrachloride), Group III (combining silymarin at a dosage of 100 mg kg-1 with carbon tetrachloride), and Groups IV–XIII (combining carbon tetrachloride with different brands of commercially available formulations). Serum levels of hepatic enzymes were analyzed to determine hepatic biochemistry and the extent of liver damage. Antioxidant activity analysis and histopathological analysis of the formulations were also conducted. The commercial formulations significantly (P < 0.01) lowered high liver biochemical markers, as validated by histological findings. Likewise, these formulations also displayed a strong antioxidant potential.
Association of Poor Bone Quality with Pseudarthrosis and Poor Clinical Outcomes in Single-Level Instrumented Lumbar Arthrodesis Using Local Autologous Bone Graft
Authors: Boden Lauren M. , Heller John G. , Fischgrund Jeffrey S.
Published: May 2024

Introduction:

Although osteoporosis and low bone mineral density is thought to lead to poor fusion outcomes, few studies have adequately addressed the correlation, and they were limited by small sample size at a single institution.

Methods:

We completed a secondary analysis of 182 patients enrolled at 26 spine centers across the United States in the EXO-SPINE FDA-approved clinical trial with 12-month CT-based fusion status determined by two independent, blinded radiologists. Using previously described CT-based techniques, we measured local and global Hounsfield units (HU) and examined the relationship with radiographic and clinical outcomes.

Results:

CT scans were available for review from 95 patients, with a mean age of 56.2 years and mean global density of 153.0 HU. No relationship was observed between HU and radiographic fusion status or clinical outcomes. Although 12% of patients had lumbar vertebral body HU measurements consistent with osteoporosis, this classification had no relation with fusion or clinical outcomes. Patients with pseudarthrosis had higher Oswestry Disability Index (22.2 vs. 16.6, P = 0.037) and back pain visual analog scale (7.0 vs. 4.9, P = 0.014) scores than patients with at least unilateral fusion at the 12-month follow-up.

Discussion:

In this large, multicenter study, lower vertebral body HU was not associated with worse fusion status after single-level instrumented posterolateral lumbar fusion using only local autologous bone graft. However, there was an association between radiographic fusion status and clinical outcomes, validating the importance of determining predictors of successful fusion. Assessment of fusion status with CT scans yielded a much lower fusion success rate with local bone graft than previously reported and may warrant additional investigation.
Factors Associated With Symptom Recurrence After Surgical Treatment of Interdigital Neuroma: A Retrospective Chart Review of 127 Patients
Authors: Ghandour Samir , Suyama Emi R. , Sirls Evan , Ahn Jiyong , Burgesson Bernard , Ashkani-Esfahani Soheil , Bejarano-Pineda Lorena , DiGiovanni Christopher W.
Published: May 2024

Introduction:

Interdigital neuroma (IN) is a benign enlargement of tissue surrounding the common plantar digital nerve. Although the standard surgical treatment of IN remains debated, recent attention has been given to less-invasive surgical decompression by intermetatarsal ligament (IML) release with neurolysis. This study aimed to compare the outcomes of IML release with neurolysis with standard interdigital neurectomy.

Methods:

A retrospective chart review was conducted on 350 consecutive patients who underwent surgical treatment of IN. Patients who satisfied our inclusion and exclusion criteria were categorized into two groups based on the surgical treatment received: IML release with neurolysis or interdigital neurectomy. Outcomes assessed included recurrence of symptoms, rate of revision surgery, and postoperative wound infection.

Results:

Of the total sample, 40 patients (31.5%) reported recurrence of symptoms within a 12-month follow-up period. Patients who underwent IML release with neurolysis had a markedly higher recurrence rate (47.50%) than those who underwent interdigital neurectomy (24.14%). The rate of postoperative wound infection was similar between the two groups. Binary logistic regression revealed that only the surgical technique was associated with the recurrence of symptoms. Despite the higher rate of symptom recurrence in the IML release with neurolysis patient group, the rate of revision surgery in those with symptom recurrence was similar between both groups.

Discussion:

IML release with neurolysis seems to have a higher risk of symptom recurrence than interdigital neurectomy. No patient-specific factors were identified as being associated with symptom recurrence. However, patients who did experience symptom recurrence in either surgical group had similar rates of revision surgery, which may be due to mild recurrent symptom severity in the IML release group that does not warrant revision surgery in these patients. Future studies should consider objective symptom recurrence severity and patient satisfaction.

Level of evidence:

Level III
6. Sınıf Türkçe dersinde drama yöntemini kullanmanın öğrencilerin sosyal beceri ve derse karşı tutumuna etkisi
Authors: Çam Türkan Çiğdem , Dinç Abdülkerim
Published: May 2024

Bu çalışmada Türkçe dersinde drama yöntemi kullanmanın öğrencilerin sosyal beceri gelişimine etkisinin yanı sıra derse karşı olan tutumlarının belirlenmesi amaçlanmıştır. Çalışmanın yöntemi olarak ön test ve son test gruplu deneysel desen ile çalışma yürütülmüştür. Araştırmada kontrol ve deney grupları oluşturulduktan sonra deney grubu ile 6 hafta, 24 saatlik çalışma yapılmıştır. Çalışma Iğdır ilinde eğitim gören bir devlet okulunda yürütülmüş olup, çalışma grubunu deney/kontrol (30/30) toplamda 60 öğrenci ile gerçekleştirilmiştir. Çalışmada gruplara eğitim öncesi ön test uygulanmıştır. Araştırmacı tarafından deney grubuna Türkçe dersi kazanımları doğrultusunda drama yöntemiyle hazırlanan öğretim süreci gerçekleştirilmiş ve yürütülmüştür. Kontrol grubuna ise herhangi bir müdahalede bulunulmamıştır. Çalışma sonunda gruplara son test uygulanmıştır. Veriler SPSS 22.0 ve IBM Amos 23 programları kullanılarak analiz edilmiştir. Çalışma sonucunda drama yöntemiyle öğretim; deney grubu öğrencilerinin derse karşı tutumlarını olumlu geliştirdiği gözlenmiştir. Sosyal becerilerin gelişiminde dramanın önemli rol oynadığı sonucuna ulaşılmıştır. Araştırma sonucunda dramanın tutum ve sosyal becerileri anlamlı düzeyde etkilediği görülmüştür.
Nghiên cứu xây dựng hệ số phát thải cho một số ngành sản xuất vật liệu xây dựng Việt Nam
Authors: Cao Thị Tú Mai  , Trung Đỗ Tiến , Tâm Nguyễn Thị
Published: May 2024

Hệ số phát thải riêng quốc gia, hệ số phát thải riêng cho ngành là một trong những công cụ đơn giản, hiệu quả và có độ chính xác cao trong việc ước tính phát thải khí nhà kính vào môi trường. Bài báo này trình bày về việc nghiên cứu phương pháp luận để xây dựng hệ số phát thải cho một số ngành sản xuất vật liệu xây dựng tại Việt Nam bao gồm gạch ốp lát, sứ vệ sinh, gạch nung và kính. Kết quả hệ số phát thải xây dựng được là 0,868kgCO2-e/kg gạch ceramic; 0,869kgCO2-e/kg gạch granite; 1,106kgCO2-e/kg sứ vệ sinh và 0,885kgCO2-e/kg kính.
Prevalence of Fatigue Among Physiotherapy Students - A Cross-Sectional Study
Authors:   Cauvery College of Physiotherapy, Mysuru, Kumar G Pavan , Souza Ilona Gracie De
Published: May 2024

Fatigue is expressed in related concepts such as 'overwhelmingly tired', 'exhausted', 'weakness', 'lassitude', 'feeble lethargy', 'lack of energy', 'wrung out' and 'mentally tired'. Persistent fatigue can cause a lack of mental clarity, difficulty in concentrating and in some cases it cause memory loss. It is the body's way of signalling need for rest and sleep. Physiotherapy being one of the flourishing courses in India as well as globally, it is both physically and mentally demanding when compared to many other medical and paramedical courses. Typical Physiotherapy practices involve repeated lifting, bending, twisting, reaching, and performing manual therapy. Thus, the current study aims at focussing on the fatigue severity rate among physiotherapy students. The study was conducted in April 2021 to Dec 2022, to know the prevalence of fatigue among physiotherapy students. Eight hundred students were recruited into the study based on the selected inclusion and exclusion criteria. The demographic data was collected and were asked to complete the visual analogue fatigue severity scale. The data was entered into the statistical package for social sciences software. To examine the baseline characteristics of the subjects, we analyzed the frequency and descriptive statistics and then it was subjected for finding of normality. Inferential analysis was carried out by using Chi- Square test for the outcomes of VAS- F. The result of the present study showed that the demographic data were not statistically significant (p>0.05). Gender and batch were not significant (p>0.05). The prevalence of fatigue was; mild 27.3%, moderate 34.2% and severe 37.9%. Keywords: Fatigue, Physiotherapist, Physical inactivity, Physical Therapy