bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis and simulation of an extended SEIR mathematical model with vaccination for the spread of SARS-COV-2
Authors:   UNMSM, Facultad de Ciencias Matemáticas, Lima, Perú., Madge Jennifer Y. , Pérez Jhelly R.
Published: August 2022

This article analyzes the dynamic of an extended SEIR model for the spread of COVID-19 considering a system of 7 differential equations whose stages are susceptible, exposed, infected, quarantined, recovered, dead and vaccinated. The necessary and sufficient conditions are determined for non-negativity, delimitation, existence and uniqueness of the solution of the model, local stability of the equilibrium points and the next generation matrix method. The simulations made in Python complement the qualitative analysis of the mathematical model to conclude the behavior of the virus spread over time; the information shown in this work could also be useful for the development of new prevention measures.
Cultural Policies and Creative Cities: concept and approaches
Authors: Pasquotto Geise Brizotti
Published: August 2022

Currently, the informational economy has become a cultural economy, which has made culture a driving force for new market demands. A variety of projects, plans and urban policies that use culture as a main theme have been disseminated in the last three decades. The use of cultural aspects has several dimensions and should be used as an element of enrichment and not as a commodity which the intended result is only profit.

The article seeks to present introductory concepts regarding culture, the culturalization of cities, cultural policies and creative cities, in order to briefly discuss this very complex field of action.
Human Knee Meniscus Collection Protocol for scRNA-seq v1
Authors: not provided molmer
Published: August 2022

Meniscus is taken from the medial knee compartment is collected for scRNA-seq processing. The attached image indicates where the meniscal tissue is collected from.
Passaging of trophoblast organoids from full-term placental tissue. v1
Authors: Coyne Carolyn
Published: August 2022

This protocol describes the passaging of trophoblast organoids isolated from full-term human placental tissue.
ES cells general methods v1
Authors: Berrens Rebecca
Published: August 2022

general methods for mouse ES cell culturing
RNA sequencing analysis of transcriptomic responses to vagal nerve stimulation in myenteric ganglia of porcine colon v1
Authors: Li Tao
Published: August 2022

The region-dependent molecular characterization and influences by vagus nerve stimulation (VNS) influences in the porcine ENS has been little investigated so far. We use laser-capture microdissection coupled with bulk RNA sequencing analysis to profile the transcriptomes of myenteric ganglia (MG) from porcine proximal and distal colon and to evaluate discrepancy of the region-specific gene programs in MG after electrical stimulation of the celiac branch of the abdominal vagus nerve in anesthetized porcine.
Media for culturing cells v1
Authors: Berrens Rebecca
Published: August 2022

common ES cell media for mouse embryonic stem cells
CRISPR puromycin v1
Authors: Berrens Rebecca
Published: August 2022

This protocol is for CRISPR knock-in generation in mouse embryonic stem cells
Measurement of Ankle Brachial Index with Oscillometric Method for Early Detection of Peripheral Artery Disease
Authors: Dewi Ervin Masita , Ramadhan Gema , Parlindungan Robinsar , Iryani Lenny , Yuwono Trisno
Published: August 2022

Peripheral Arterial Disease (PAD) is a blood vessel disease caused by blockage or plaque accumulation around the artery walls. PAD is included in the category of diseases that are often diagnosed too late and affect more severe cases, such as the death of certain tissues or body parts. The Ankle Brachial Index (ABI) is an accurate non-invasive method for diagnosing PAD, in practice, ABI is usually performed in certain hospitals and is still difficult to find due to limited tools. Therefore, a tool is made that can detect the condition of a person's PAD based on the ABI value. The tool is made using two MPX5050GP sensors to detect oscillometric pulses, a DC pump and solenoid valve as an actuator to pump and deflate the cuff, ADS1115 as an external ADC to increase the accuracy of sensor readings, as well as an LCD and buzzer as tool indicators. The output is displayed in the form of a print out from a thermal printer, with an emergency stop that functions as a safety system to power off the supply when a failure occurs in the measurement process. Oscillometric method is used to detect systolic and diastolic pressure. The accuracy of the tool is 95.5%. This accuracy result is obtained by comparing the readings of systolic and diastolic values using a sphygmomanometer which is commonly used.
Formei, e agora? Refletindo com os egressos do curso de Turismo da UFJF sobre o mercado de trabalho na cidade de Juiz de Fora/MG em tempos de pandemia
Authors: Vieira Carine Simas , Moraes Edilaine Albertino de , Arcuri Alice Gonçalves , Rosa Anne Bastos Martins
Published: August 2022

O presente trabalho tem como objetivo apresentar uma análise do mercado de trabalho em turismo na cidade de Juiz de Fora (MG), sob a ótica dos alunos formados no Curso de Turismo pela Universidade Federal de Juiz de Fora (UFJF), no período de 2015 a 2020. A metodologia foi composta por pesquisa bibliográfica, documental e realização de entrevistas semiestruturadas através de formulário on-line com os alunos previamente selecionados. Diante dos resultados, foi possível compreender as áreas de atuação em que esses profissionais estão inseridos, quais foram suas expectativas, percepções e as dificuldades, possibilidades e desafios encontrados no processo de inserção no mercado e de manutenção das atividades em tempos de pandemia de Covid-19. Assim, conquanto o turismo se revele como uma área profissional com possibilidades de atuação no mercado de trabalho na cidade, principalmente na ênfase de gestão, ainda enfrenta oportunidades limitadas, com a desvalorização e o não reconhecimento desses trabalhadores com capacidade de exercer as competências, os conhecimentos e as habilidades atribuídas à sua formação superior.
Reputação Online x Classificação Oficial de Meios de Hospedagem
Authors: Valduga Manoela Carrillo , Martins Verônica Pereira , De Oliveira Jamila Tulani Pinho , Da Costa Mariana Cordeiro
Published: August 2022

Tradicionalmente, a classificação hoteleira é dividida entre três formas: a oficial, a independente e a comercial. A reputação online, que é contabilizada pela extração dos temas textuais mais recorrentes associados à satisfação e insatisfação dos clientes, expressos em comentários de hóspedes em sites colaborativos e/ou de reservas de hospedagem, vem tomando cada vez mais espaço em estudos acadêmicos e relevância como ferramenta de gestão de meios de hospedagem. Nesse contexto, o objetivo deste artigo é identificar o impacto das avaliações online e consequente reputação dos meios de hospedagem nos diferentes tipos de classificação hoteleira, de acordo com a opinião de onze experts sobre os temas de meios de hospedagem e/ou de reputação online atuantes no mercado e/ou na academia, no Brasil. A metodologia empregada para a verificação da opinião dos experts foi de natureza qualitativa e contou com entrevistas estruturadas para a coleta dos dados e análise de conteúdo com o uso da ferramenta Taguette. Como resultado, confirmou-se a reputação online como fator de maior relevância na escolha por um meio de hospedagem e a descrença na utilidade da classificação oficial, de acordo com a opinião dos experts.
APPROXIMATION OF GUARANTEES OF INDEPENDENCE OF PROSECUTORS AND JUDGES IN UKRAINE: IN SEARCH OF PREREQUISITES AND TRENDS
Authors:   Taras Shevchenko National University of Kyiv, Stefanchuk М.
Published: August 2022

Some aspects of the convergence of guarantees of independence of prosecutors and judges in Ukraine, due to constitutional changes in the judiciary, are highlighted in the paper. The purpose of the article is to sort out the prerequisites and identify trends in the convergence of guarantees of independence of prosecutors to judges at the current stage of reforming the justice system. It is established that the current scientific discourse on the issue of institutional determination of the place of the Prosecutor's Office in the mechanism of state power is mainly to determine the benefits of the autonomous status of the Prosecutor's Office, in which it doesn't belong to any branch of government, and holds the status of an autonomous body within the judiciary. It is argued that the institutional recognition of the Prosecutor's Office as an autonomous and independent body of the judiciary is more promising for the purpose of bringing the legal status of the prosecutor closer to the legal status of the judge, considering the interdependence of their powers and the need to ensure proper justice. It is stated that international standards define the independence of the Prosecutor's Office as an unconditional consequence of the independence from the judiciary and declare the prosecutors to have guarantees similar to those of judges, given by the proximity of the missions of judges and prosecutors, particularly, regarding the appointment, transfer, promotion and the application of disciplinary sanctions. As a result, it is proposed that the formation of bodies that determine the level of professional training of persons who intend to take the position of a prosecutor or judge, as well as resolve issues of disciplinary liability of prosecutors and judges together with their transfer and dismissal to be as close as possible. The peculiarities of legislative regulation of the formation of judicial and prosecutor's governance at the current stage of reforming the justice system in Ukraine are analyzed. It was found that the tendencies towards convergence of these processes in relation to prosecutors to the level of judges are weakening. It is proposed to create a single judicial and prosecutor's governance to address career and discipline issues, which will harmonize and simplify the structure of judicial governance in Ukraine, as well as unify these procedures for prosecutors and judges as key public officials of the justice system.
LEGISLATIVE FORM OF GAMING BUSINESS PUBLIC GOVERNANCE
Authors:   Taras Shevchenko National University of Kyiv, Toporetska Z.
Published: August 2022

The article deals with the form of public governance of gambling in Ukraine from 2020 – the state monopoly on the organization and conduct of gambling. Based on the generalizations of the world's existing forms of public management of gambling, it was concluded that the state monopoly is the most successful model of public administration for our state. But the form of its implementation (a kind of state monopoly) is manifested, considering the historical development of our country, the peculiarities of its society, the tendency of the population to form gambling addiction, society's attitude to gambling, forms of government and more. Today, Ukraine is introducing a second type of state monopoly – free access to the gambling market for companies (subject to organizational and qualification requirements), while limiting the maximum number of gambling establishments that can operate simultaneously in the country. At the same time, in the future it is possible to combine this type with special territorial gambling zones (the Cabinet of Ministers has the right to determine no more than five of them on the territory of the state). Based on the study, the author offers to improve national legislation on gambling taxation and to introduce the idea of social utility of public gambling management for the full implementation of Ukraine's chosen model of state monopoly. Keywords: gambling business, organization and conduct of gambling, state monopoly, special gambling zones, gambling establishments
Citation Analysis of Ph.D. Theses Submitted to the University of Delhi in Social Sciences During 1995-2008
Authors: Singh K. P. , Bebi  , Garg K. C.
Published: August 2022

The study presents an analysis of citation pattern of Ph.D. theses in social sciences awarded by the University of Delhi during 1995-2008. The study identifies how the pattern of submissions has changed during 1995-2008 in different disciplines of social sciences, besides studying distribution of citations by document types, pattern of authorship of cited documents, cited Indian and foreign authors and chronological distribution of citations. The ranked lists of core journals also have been presented. The analysis reveals that 51,889 citations were made to 259 theses in social sciences. The analysis of these citations shows that books are the most preferred source of citations in all disciplines except economics and constitutes about 55.5% of total citations. The authorship pattern reveals that single authored citations constitute about 86 per cent citations. The chronological distribution of citations shows that the period ranging from 1991 to 2000 is the most cited period. The analyses of journals ranking shows that Economic and Political Weekly published from India is the most cited journal.
Assessing Information Literacy Competency in Higher Education: A Study of Panjab University, Chandigarh
Authors: Mahajan Preeti , Kumar Anil
Published: August 2022

The purpose of this paper is to assess basic information literacy competency and the perception of information literacy behavior of post-graduate students and research scholars at Panjab University, Chandigarh. A structured questionnaire was designed to collect the primary data from the respondents and results were analyzed and presented in the tabulated form. The findings of the study discussed and necessary suggestions have been made on the basis of the results for implementing proper information literacy competency programmes at Panjab University, Chandigarh. The study has been found that students require competency to solve information related problems.
Geographical Indications: A Brief Appraisal of Indian Scenario
Authors: Chikate Anil Nanaji , Gadge-Chikate Sharmila V.
Published: August 2022

Intellectual Property (IP) is the creation of human intellect and an asset to be bought, sold, mortgaged, licensed, exchanged or gratuitously given away like any other form of property. The creator of the IP seeks exclusive right and property to be used by others only after owner consent. Geographical Indication is an emerging trend in intellectual property. Geographical indications (GIs) of goods are basically industrial property referred to a country or a place situated in the country or place of origin of product. Every region has its identity through qualities of certain goods or commodities attributable to geographical locations and reputable as produce of certain region. The present paper takes an overview and analysis of the current scenario of geographical indications in India registered till July 2011.
Reordering Ranganathan: Shifting User Behaviours, Shifting Priorities
Authors: Connaway Lynn Silipigni , Faniel Ixchel M.
Published: August 2022

S.R. Ranganathan's Five Laws of Library Science provide a broad framework for designing and evaluating library programmes, activities and services. The laws continue to be extensively cited even today suggesting their continued relevance. This paper attempts to interpret the five laws in the present day context of information abundance, digital revolution, currently available resources and services, and user behaviours. The idea has been to suggest how libraries and librarians can better connect to those behaviours. After examining the changing roles of the Five Laws on the basis of findings of recent research, the paper suggests reordering and reframing of the Five Laws of Library Science. A number of recommendations for realizing the intent of the laws have also been made.
Awareness and Use of Internet Based E-Information Resources among School Children: A Case Study of Bijapur District, Karnataka
Authors: Kulkarni Deepa R. , Tadasad P. G.
Published: August 2022

The present study investigates the awareness and use of internet based e-information resources among school children in two selected schools of Bijapur of Karnataka State. Based on a survey of 120 students, the study emphasizes the awareness and use of e-information sources. It assesses and analyzes the acquaintance of school children with IT, awareness and use of internet, problems encountered awareness about searching e-information sources, types of sources preferred, reasons for not using e-information sources, channels preferred, and ability of them to use e-information sources.
Indian Forensic Science Research Literature: A Bibliometric Study of its Growth, Authorship and Publication Patterns
Authors: John Jeyasekar J. , Saravanan P.
Published: August 2022

A bibliometric analysis of the growth, authorship and publication patterns of forensic science literature for the period 2001 to 2013 was done using the data obtained from PubMed. MS-Excel worksheet was used for data analysis. The study revealed the exponential growth of forensic science literature. The relative growth rate fell from 0.83 in the year 2002 to 0.17 in the year 2013. The mean collaborative Index was 3.5; mean degree of collaboration was 0.89; mean collaborative coefficient was 0.6119 and mean modified collaborative coefficient was 0.6121 during the period of study. Forty one authors have contributed more than one percent of the total publication. Ten journals have contributed more than one percent of the total papers. Among these 'Journal of Forensic&Legal Medicine' ranks first with 16.10% papers. Cluster map of co-words was also created using VOSviewer.
Medical Professionals’ Usage and Preference of EBM Resources: A Survey
Authors: Jessy A. , Rao Mahabaleshwara , Shivananda Bhat K.
Published: August 2022

A survey was undertaken to study how the medical professionals of clinical departments of Kasturba Medical College (KMC), Manipal, utilize the Evidence Based Medicine (EBM) resources provided by the KMC Health Sciences Library, Manipal and to identify their preferred EBM resources. A questionnaire survey was carried out to collect the information. From 74 respondents, 20 were medical faculty and 54 were pursuing postgraduate courses in different medical subject areas in clinical departments. The questionnaire was designed to collect demographic details of participants, general information regarding the usage of EBM resources and the factors leading for the selection of the most preferred EBM resource. A large segment of the participants were familiar with the EBM resources available in the library and few of them were also familiar with EBM resources available through other sources. The data on the pattern of EBM resources utilization revealed that PubMed was the resource accessed daily by the most number of faculty and UpToDate by Postgraduate (PG) students. The most preferred EBM resource by both faculty and PG students was UpToDate. The details of the data analysis, results and the major findings are presented in this article.
Facebook Posts and Lotka's Law
Authors: Harinarayana N. S. , Kousar Anjum , Sunil M. V. , Vasantha Raju N.
Published: August 2022

Facebook is an online social networking site. It allows registered users to create profiles, upload photos and video, send messages and keep in touch with friends, family and colleagues. It is a very popular social networking site. Librarians use it for official and personal communication purpose. The present study examines the participation of librarians in Facebook by testing whether it follows the pattern given by Lotka's law. The result shows that it does not. The paper analyses the reasons and also provides the methods of collecting data for bibliometric study.
Social Networking in Library and Information Services:Current Scenario
Authors: Ansari Aslam , Nazim Mohd.
Published: August 2022

Social Networking (SN) began from late 20th Century and is growing up rapidly. It works as a medium of communication with one to another for sharing their experiences and information regarding their interest, and also helps to build up longtime relationship between individuals and groups. In the field of LIS services, it may help to promote the services of LIC (Library and Information Centers). This study provides the efficient account of SN tools and how it affects communication with others. The findings disclose that some SN tools are gaining popularity among LIS professionals as they use at least one of Social Networking Sites (SNS). The most active professionals are from younger generation between the age group of 26-35 years. The professionals opine that SNS is very effective to deliver the services of LIC.
Career Inforamtion Needs and Use of Library Facilities among Women Career Seekers
Authors: Gothe Geeta , Tadasad P. G.
Published: August 2022

Career information is an important and key resource for any individual to decide one's career goal. This study deals with the identification of the career information needs of and library facilities usage by women of Savanur Taluk of Haveri District in Karnataka state. Data were collected through survey method of research by using questionnaire as data collection tool from 60 educated women of Savanur. This study assesses the career information needs of women and different types of libraries used by them and it also brings out the reasons why women are not accessing the career information from libraries. Also mentions suggestions to improve library facilities to provide effective library services on career information.
Atenção Odontológica à Pessoa Surda: uma Revisão da Literatura
Authors: Rocha Gabriela dos Santos Ribeiro , Sako Thais Akemi , Goya Suzana
Published: August 2022

De acordo com o Instituto Brasileiro de Geografia e Estatística (IBGE), 9 milhões de brasileiros apresentam deficiência auditiva, de dificuldade até a ausência total de audição. O objetivo é discutir sobre a atenção odontológica prestada à pessoa surda, desde oatendimento clínico, até a educação em saúde bucal. As buscas foram realizadas nas bases de dados Lilacs, Medline e SciELO, e as palavras-chaves foram Comunicação, Línguas de Sinais, Odontologia, Relações Dentista-Paciente e Surdez. Foram selecionados artigos que correlacionavam a prática odontológica, o ensino da odontologia e a assistência em saúde bucal do paciente surdo. Foram incluídos 15 artigos dos quais foram divididos nas seguintes categorias: atendimento clínico, avaliação das condições bucais, cultura surda na educação de graduandos e profissionais da odontologia, educação em saúde bucal, percepção sobre saúde bucal e atendimento odontológico. Após a revisão percebeu-se que há uma escassez de estudos relacionando odontologia e surdez, além de despreparo das instituições de ensino superior   no manejo do paciente surdo.
 
Palavras-chave: Comunicação. Línguas de Sinais. Odontologia. Relações Dentista-Paciente, Surdez.
 
Abstract
According to the Brazilian Institute of Geography and Statistics (IBGE), 9 million Brazilians have some hearing impairment, since some hearing loss to complete deafness. This study aims to discuss the dental assistance offered to the deaf person, since the dental appointment until oral health education. The research happened on the databases Lilacs, Medline and SciELO, the keywords were Communication, Sign Language, Dentistry, Dentist-Patient Relations, and Deafness. Studies that related the dental practice or dentistry teaching e oral health assistance of deaf patients were included. Fifteen articles were included and divided into categories: clinical care, assessment of oral conditions, deaf culture on the education of students and dentistry professionals, oral health education, and perception about oral health and clinical care. There are just a few studies matching the dentistry and deafness, also the education institutions of dentistry are not ready to assist the deaf patient and need to expose their students to the deaf culture.
 
Keywords: Communication. Sing Language. Dentistry, Dentist-Patient Relations. Deafness.
Melatonina em Animais de Companhia: uma Revisão de Literatura
Authors: Mondes Pedro Henrique de Lima , Tamura Eduardo Koji
Published: August 2022

A melatonina, N-acetil-5-metoxi-triptamina, é uma indolamina que possui diversas ações no organismo, desde regulação de ritmos circadianos, modulação do sistema imune, indutor do sono em determinas espécies e até eliminação de radicais livres. O objetivo desta revisão foi descrever o histórico, a síntese, os mecanismos de ação e os efeitos da melatonina, além de descrever trabalhos que utilizaram a melatonina em patologias associadas aos animais domésticos, em especial, nos cães e nos gatos. Esta revisão pode ser classificada como integrativa, com metodologia que consistiu em selecionar artigos das plataformas online como PubMed e Google Acadêmico, com a combinação de palavras-chave como “melatonin”, “dog”, “cat”, “circadian”, “rhythm”, “mammals”, desde que investigassem o envolvimento da indolamina na fisiopatologia de animais de companhia, ou que utilizassem a melatonina como método terapêutico no campo da Medicina Veterinária. Os artigos escolhidos dataram de 1958 até 2020. Os resultados demonstraram efeitos diversos, em várias áreas de especializações da veterinária, entre essas, oncologia, oftalmologia, anestesiologia, reprodução, endocrinologia, neurologia, dermatologia e gastroenterologia. Apesar dos resultados obtidos, a melatonina ainda é pouco estudada em trabalhos clínicos e científicos veterinários e, por isso, necessita de mais investigação, uma vez que possui potencial terapêutico em muitas das enfermidades que acometem animais de companhia.
 
Palavras-chave: Glândula Pineal. Medicina Veterinária. Cães. Gatos. 
 
Abstract
Melatonin, N-acetyl-5-methoxy-tryptamine, is an indolamine that has various effects in the organism, from regulation of circadian rhythms to immune system modulation, sleep induction in some species and to scavenger of free radicals. This review aimed to described the history, action mechanisms and melatonin effects, in addition to, also describe studies focusing in therapeutic use of melatonin in pathologies associated with companion animals, specially dogs and cats. This review can be classified as integrative, with a methodology consisting of selected articles from online platforms, PubMed and Google Scholar, using the combination of keywords such as “melatonin”, “dog”, “cat”, “circadian”, “rhythm”, “mammals”, since they investigate the  indolamine involvement in the companion animals pathophysiology, or that use melatonin as a therapeutic method in the Veterinary Medicine field. The selected articles were from 1958 to 2020. The results demonstrated different effects in some veterinary specialization areas, including oncology, ophthalmology, anesthesiology, reproduction, endocrinology, neurology, dermatology and gastroenterology. Despite the results obtained, melatonin is still  poorly studied in clinical and scientific veterinary and, therefore, needs further investigation, since it has therapeutic potential in many diseases that affect companion animals.
 
Keywords: Pineal Gland. Veterinary Medicine. Dogs. Cats.
HISTORICAL-COMPARATIVE MULTICULTURALISMS: REVOLT AGAINST PERSECUTION BY ACHAEMENIDS AND ABBASIDS
Authors: MENEK İbrahim Halil , TOPCU Emel
Published: August 2022

This study covers the research of the Achaemenid Empire and the early Abbasid Dynasty period, which are examined as two historical examples of multiculturalism based on the framework of the comparative historical method. The analysis have indicated that both Achaemenid (Persian) Empire and the early period of the Abbasid Dynasty (750-833) showed similarities in terms of ending oppressive and assimilations policies of previous civilizations, grabing the power after a revolution that broke out against social stratification and applying religious freedom policies despite the driving force of a monotheistic religion. These characteristics contributed to the transformation of both empires, which contributed to the emergence and flourishing of multiculturalism. Comparative analysis of these two historical examples of multiculturalism, in the study, based on the data obtained from the literature review within the framework of the comparative historical method, indicate that the two empires shared multicultural similarities.
Postcovid bronchoobstructive syndrome in practice of general practitioner and pulmonologist: large-scale study
Authors: Leshchenko I. V. , Esaulova N. A.
Published: August 2022

It is hard to make a conclusion about relationship between Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and Bronchoobstructive Syndrome (BOS) in the postcovid period based on the literature.

The aim. To determine the optimal treatment approaches by conducting a comprehensive assessment of clinical, laboratory and functional parameters, taking into account the risk factors for the development of BOS.

Methods. 10,456 patients with Coronavirus Disease-19 (COVID-19) were examined, and 7,459 patients were randomized into 2 groups with a newly diagnosed BOS. Group 1 (n = 3,245) was prescribed beclomethasone/formoterol (BDP/FORM) as Maintenance And Reliever Therapy (MART). Group 2 (n = 4,252) was prescribed budesonide suspension (BUD) and salbutamol solution (SAL). The study assessed severity of COVID-19, presence of atopy and frequency of acute respiratory viral infections (SARS) in the medical history, spirometric parameters, blood eosinophils, Asthma Control Questionnaire-5 (ACQ-5) score, use of pro re nata medications, and adverse events.

Results. Patients who had mild COVID-19 were diagnosed with BOS at weeks 8 – 24 (73.3%), while patients with moderate or severe COVID-19 were diagnosed at week 4 (54.9%). Virus-induced BOS (VI BOS) was diagnosed in 71.8% of the cases. 13% of the patients with BOS in postcovid period were diagnosed with asthma.

Conclusion. The incidence of BOS is significantly higher in patients with atopy and history of frequent SARS who had moderate or severe COVID-19. A fixed combination of extrafine BDP/FORM as MART was superior to nebulized BUD + SALM in the treatment of VI BOS.
Comparative study of combination of misoprostol with Foley’s bulb compared with misoprostol alone for termination of second trimester pregnancy
Authors: Agarwal Priya , Gandhi Sudha , Indora Prachika
Published: August 2022

Background: Second trimester abortion is termination of pregnancy in a period from 13 to 28 weeks of gestation. Second trimester losses may be due to maternal factors such as uterine malformation, growths in the uterus (fibroids), or cervical problems. These conditions also may contribute to premature birth.  Aims and objectives were to compare the efficacy, safety and suitability of combination of misoprostol with intracervical Foley’s catheter v/s misoprostol alone for termination of second trimester pregnancy.Methods: This randomized controlled trial study was conducted on 100 study subjects who passed our inclusion and exclusion criteria. Group A: received misoprostol with intracervical Foley’s catheter. Group B: received misoprostol alone. The groups were compared with respect to the patients’ characteristics, gestational age, indication for termination of pregnancy, rate of complications, etc.Results: Mean value of age (years) of study subjects was 27.12±4.5. Mean induction to delivery time (hours) in P0 was 17.73±6.46 and in P1-P2 was 14.78±4.9 which was significantly higher as compared to ≥P3 (11.46±3.82). (p=0.0004). Mean induction to delivery time (hours) in 14 to 18 weeks was 15.25±5.4 and >18 weeks was 15.02±5.84. (p=0.854). Distribution of side effect between group A and B. (6% vs 20% respectively) (p=0.041).Conclusions: We conclude that intracervical Foley catheter and vaginal misoprostol is a safe and effective method for second trimester abortion as compared to misoprostol alone group with no additional risks.
Observational study for the functional outcome of humerus shaft fractures treated with plating versus nailing
Authors: Bal Gurwinder Singh , Sandhu Harinder Singh , Chaudhary Anil Kumar , Sandhu Amandeep Kaur
Published: August 2022

Background: Fractures of the humerus diaphysis comprise approximately 3% of all fractures. It’s treatment has mainly been conservative in the past but is not well tolerated by the patient now a days. Also, all humerus shaft fractures are not amenable to conservative methods. Operative interventions like dynamic compression plating and intramedullary nailing are associated with better functional outcome. There has been a lot of debate on which of the above two surgical methods is better for management of humeral shaft fractures to ensure better functional outcome and lesser complication rate. Objective were to compare the results of the plating and nailing in the treatment of humerus shaft with reference to A) functional outcome and B) complications and their management.Methods: All patients with fracture of humeral shaft presenting to the department of orthopaedics, MMIMSR, during the study period and that met our criteria were included in the study. Out of total 30 patients, 15 were randomly selected for intramedullary nailing and 15 for plating. Postoperatively, these patients were followed up for 6 months and relevant data was collected. Time taken for union, post operative complications rate and final functional outcome were then compared in the two groups. Study design was observational study.Results: It was observed that most of the patient that sustained humeral shaft fractures were 18-40 years of age. Post-operatively, fractures treated by plating united earlier, had lesser complications and significantly better functional outcome compared to nailing.Conclusions: We concluded that plating is a better method and more acceptable to patients as compare to intramedullary nailing for the treatment of fractures shaft humerus, as it is associated with better functional outcome, earlier union of fracture and lesser complication rate.
Adolescent well-being during the COVID-19 pandemic in India
Authors: Vyas Amita N. , Nagaraj Nitasha C. , Chandarana Shikha , Landry Megan M.
Published: August 2022

Background:It is without question that gender attitudes/norms, voice and agency, self-efficacy, and locus of control are important determinants of health and well-being, particularly for adolescent girls and boys in low to middle income countries. And, while prior to the COVID-19 pandemic, there were trends suggesting social inequities would be on the decline, these trends have since reversed due to abrupt long-term school closures as a result of the pandemic. This study examines adolescents’ perceptions of gender norms/attributes, voice/agency, self-efficacy, locus of control, and gender-based violence norms pre-COVID and one year later during the COVID-19 pandemic and subsequent lockdown in India, a country with one of the largest adolescent populations worldwide.Methods: The data for this study were derived from a larger study via two cross-sectional self-reported survey of adolescents ages 10-15 years old in public schools located in Delhi, India (urban), and Uttar Pradesh, India (rural) pre-COVID and one year later. The adolescent participants were part of local existing after-school programs and interventions implemented by non-profit community organizations, and a convenience sample (n=547) was recruited.Results: The present study found that positive gender attributes, positive gender norms, GBV norms, voice, and locus of control all worsened between the two time periods-pre-COVID-19 and one year later during the height of the COVID-19 pandemic.Conclusions: As India looks ahead to rebuilding after the pandemic, it will be imperative that attention is paid to gender perceptions and attitudes, empowerment, and family/gender violence as a result of the short and longer impact of COVID-19.
Utility of haematological parameters and NESTROFT as screening tools for thalassemia trait- A study in a tertiary care hospital
Authors: Kini Sangeeta , Kamat Rima , Gatlewar Shilpa
Published: August 2022

Thalassemia being one of the commonest causes of anaemia, screening remains is the backbone for diagnosing traits. Considering expensive confirmatory diagnostic tests, aim of this study was to study utility of haematological parameters and NESTROFT as screening tools for thalassemia trait.

It is a one and half year prospective study from June 2017 to December 2018, carried out in outdoor patients investigated in central laboratory of a tertiary care centre. A total of 5000 cases were randomly selected based on low haemoglobin values as per WHO Criteria. All the haematological parameters of the complete hemogram performed, were thoroughly analysed. Mentzer Index (MI) and Ehasani Index (EI) were calculated. NESTROFT was performed in all study samples and results were compared with haematological parameters. Results were compiled and statistically analysed.

Out of total 5000 cases with low haemoglobin, mean haemoglobin was 10.12+1.29. Age ranged between 1-82 years with mean age 36.22+16.50 years with female preponderance. NESTROFT was positive in 152 cases (3.04%) and haematological parameters such as RBC, Hemoglobin, MCV were found to be significant (p<0.05) in those cases. The sensitivity, specificity, PPV and NPV of MI and EI with NESTROFT was found to be 94.74%, 89.77%, 22.50%, 99.82% and 94.74%, 89.44%, 21.95%, 99.82% respectively.

This study concludes that both haematological parameters and NESTROFT have to be used in conjunction as the primary screening tool for thalassemia traits in general population. Thus making it an ideal contender to be adopted in rural settings of developing countries, for early diagnosis and decreasing the morbidity associated with thalassemia.
To compare effects of pretreatment with two doses of dexmedetomidine on etomidate induced myoclonus and attenuation of stress response at intubation
Authors: Bhatia Parminder Singh , Gupta Priyanka , Kumari Santosh , Chauhan Renu
Published: August 2022

Etomidate’s haemodynamic stability is due to its unique lack of effect on the sympathetic nervous system and on baroreceptor function. Even in cardiac patients an induction dose of etomidate results in very stable haemodynamics. Etomidate also has minimal effects on respiratory system as compared to other induction agents. Since it causes minimal histamine release, this gives an advantage in patients with reactive airway disease, making it less likely that they will have bronchospasm. However, pain on injection and myoclonus are two most common side effects of this drug. Pain on injection has disappeared after the new fat emulsion of etomidate, but the new solvent has not reduced the incidence of myoclonus.

1): To compare the effects of pretreatment with two doses of Dexmedetomidine on the incidence of Etomidate induced myoclonus using numerical based grading; 2): To compare the effects of pretreatment with two doses of Dexmedetomidine on attenuation of stress response at laryngoscopy and intubation after induction with Etomidate.

Study area: The proposed study was carried out in the Department of Anesthesiology and Intensive care at a tertiary care teaching hospital, after seeking clearance from the college ethical committee and obtaining written informed consent from patient. Study design: Prospective Interventional Randomized Comparative Study Study period: 1 year

It was a prospective and interventional randomized comparative study where 180 patients with age group 18-65 years, of either sex,ASA grade I & II, BMI, undergoing elective surgical procedures under general anaesthesia with endotracheal intubation were included in the study. They were divided into three groups where patients were randomly allocated into one of the three groups using Block Randomization with sealed envelope system. In Group 2 and 3, 78.3% and 76.6% patients did not have myoclonus during induction with etomidate. Stress response to intubation was suppressed by dexmedetomidine.

Based on the observations of our study, we conclude that pretreatment with 0.5µg/kg and1µg/kg Dexmedetomidine significantly reduce etomidate induced myoclonus and stress response at intubation. However, dexmedetomidine in dose of 0.5µg/kg is associated with fewer side effects of bradycardia and hypotension.
Disputas por agua entre el Complejo Industrial Pastejé y Los Reyes Jocotitlán, Estado de México (México): espacialización industrial e hídrica a escala regional
Authors: Rodríguez Sánchez Antonio
Published: August 2022

Se analiza el impacto que tuvo la gestión, aprovechamiento del agua y el proceso de industrialización en el municipio de Jocotitlán, Estado de México, entre 1940-1980. Además, se identifican las disputas relacionadas con la apropiación del agua protagonizadas por el ejido Los Reyes y el Complejo Industrial Pastejé. Para el análisis se realizaron cuatro entrevistas a profundidad y se consultaron documentos de archivo. Se encontró que el ejido Los Reyes vivió dos episodios que afectaron su producción agrícola y acceso al agua: la irrupción del Complejo Industrial al municipio y la segunda etapa de transferencia de agua al entonces Distrito Federal. Los resultados sugieren que las disputas por el control del agua en la región son procesos emergentes derivados de la relación entre las instituciones encargadas de la política hídrica nacional y actores hegemónicos, cuya interacción produce un espacio a escala regional.
Dispersión transnacional de la vulnerabilidad: reexaminando la migración en el desarrollo periférico
Authors: Fresneda Camacho Edel J.
Published: August 2022

El objetivo de este artículo es examinar la utilidad del concepto Dispersión transnacional de la vulnerabilidad, para dar cuenta del vínculo que existe entre las etapas de un ciclo migratorio que surge de la naturaleza desventajosa de desarrollo y las condiciones de marginación y vulnerabilidad presentes en esa naturaleza. Se expone la vulnerabilidad como un concepto cardinal que permite comprender los tipos de condicionamientos que tiene la migración en los mismos contextos. Concepto que, además, consiente el diálogo entre teorías; cuando es comprendido como una consecuencia de la heterogeneidad y los desequilibrios del desarrollo que son resultantes de una integración desigual entre los países; secuela desde la cual los individuos elaboran interpretaciones y estrategias que influyen en la trayectoria migrante posterior.
Heterotopías de la decencia. Los hoteles de paso en la ciudad de México a mediados del siglo XX (1952-1966)
Authors: Luna Elizarrarás Sara Minerva
Published: August 2022

Este artículo revisa la configuración de la categoría no oficial “hotel de paso” para aquellos establecimientos de hospedaje que albergaron predominante o exclusivamente prácticas sexuales en un contexto marcado por recurrentes expresiones de pánico moral y las acciones “moralizadoras” impulsadas por el Departamento del Distrito Federal, encabezado por el sonorense Ernesto P. Uruchurtu (1952-1966). Este texto muestra que los establecimientos identificados en esa categoría generaron tensiones entre autoridades y vecinos, que estuvieron atravesadas por la diferencia socioespacial. Al caracterizarlos como antítesis y, por tanto, heterotopías de lo decente, los denunciantes buscaron afirmar su diferencia social y ratificar las prescripciones normativas en torno a la familia y la sexualidad femenina. Con ello, este trabajo contribuye a la historiografía urbana y de género, así como a las cartografías de la sexualidad en la capital mexicana.
A roadmap to the mobility and logistics trends that are reshaping Latin America and the Caribbean
Authors: Calatayud Agustina , Constance Paul
Published: August 2022

Today, governments are acutely aware that merely building new infrastructure is not the solution, and they are seeking the IDB Groups assistance in designing smarter transportation services that will meet their peoples expectations. This document describes the five broad shifts that are driving the IDB Groups transportation portfolio: (i) the social dimension of transportation services; (ii) new institutional and regulatory arrangements; (iii) logistics performance; (iv) secure resources for maintaining transport infrastructure, and (v) the digital transformation.
Signo de Chilaiditi como hallazgo incidental en un paciente con enfermedad respiratoria: reporte de caso
Authors: Estévez-Ramírez Gloria Marcela , Jiménez-Andrade Viviana Catalina , Fajardo-Rivero Javier Enrique
Published: August 2022

El signo de Chilaiditi es un hallazgo radiográfico infrecuente que consiste en la interposición de un asa intestinal entre el hígado y el diafragma. No existe etiología claramente establecida; sin embargo, se han planteado varias hipótesis que explican su presencia, entre ellos la hiperlaxitud de los ligamentos suspensorios del hígado, el aumento de la presión intraabdominal y la redundancia colónica. Al asociarse este hallazgo con síntomas gastrointestinales o respiratorios se denomina síndrome de Chilaiditi, y su tratamiento principalmente es sintomático, en casos excepcionales requiere abordaje quirúrgico. Este signo se encuentra usualmente de manera incidental y se ha visto una relación con enfermedad respiratoria crónica; pudiendo afectar su curso clínico, motivando a profundizar en el estudio integral. Se presenta el caso de un paciente adulto mayor, en seguimiento médico por enfermedad pulmonar obstructiva crónica, cuya radiografía de tórax evidencia la interposición de un asa intestinal entre la cúpula diafragmática derecha y el hígado. MÉD.UIS. 2018;31(3):57-61.
Cartas de Inábeis da Bahia (Século XX): descrição da sintaxe das relativas
Authors: De Oliveira Novais Carneiro Zenaide , Fagundes de Oliveira Lacerda Mariana , De Oliveira Costa Mascarenhas Janaina
Published: August 2022

Este artigo descreveu e analisou as sentenças relativas em 91 cartas pessoais, escritas entre 1906 e 2000, por sertanejos baianos semialfabetizados, editadas por Santiago (2012), que os define como inábeis (MARQUILHAS, 2000). Sob a orientação da Linguística Histórica Sócio-Histórica (MATTOS E SILVA, 2008) e da Sociolinguística Laboviana (LABOV, 1972), concluiu-se, após a análise dos dados levantados, que as estratégias de relativização utilizadas por esses escreventes estão próximas das variantes populares do PB (TARALLO, 1983; 1993); e, também, tendo em vista os estudos sobre aquisição de escrita, observou-se que tais processos são comuns a indivíduos adultos em fase de aquisição de escrita, como ocorre com crianças (LESSA DE OLIVEIRA, 2008).
Axiotopônimo: proselitismo político-ideológico (implícito) no Maranhão?
Authors: Nascimento Neto Reginaldo
Published: August 2022

Este artigo pretende considerar a concepção de que nomear e existir compõe uma associação de sentidos afins. Discorre-se então sobre a interdependência dos processos onomasiológicos e semasiológicos sob o ponto de vista do signo como representação metafórica da realidade. Discute então que a toponímia pode ser usada como propaganda de celebridade política, para então, concluir que o emprego de axiotopônimos no estado do Maranhão pode ser um instrumento proselitista de perpetuação ideológica implícita do poder. A análise do corpus está centrada no município maranhense de Presidente Sarney.
Atribuição de género gramatical por aprendentes de PLNM em palavras sufixadas
Authors: Rio-Torto Graça , Ferreira Tânia
Published: August 2022

Neste estudo, pretende-se indagar em que medida a atribuição de género gramatical em nomes sufixados, por aprendentes de Português europeu como Língua não Materna (PLNM), varia em função do sufixo e, mais especificamente, da classe formal deste e da marca de género associada. A base empírica deste estudo foi extraída de um inquérito, no qual se solicitava a aprendentes tardios, falantes nativos de chinês, a frequentar turmas de diferentes níveis de aprendizagem (de B1 a C1), que explicitassem o valor de género nominal de nomes sufixados em -ção, -s[z]ão, -ão, -agem, -idade e -ice. Registaram-se padrões idênticos em todos os níveis de aprendizagem, mas há uma incidência assinalável de desvios em formas sufixadas em -ão e -ice. Estes resultados mostram que a atribuição de um valor de género ao nome depende do grau de representatividade e de opacidade do sufixo no input e do respetivo valor de género associado.