bluuebunny/crossref_metadata_2025 huggingface dataset:
Molecular epidemiology of Clostridioides difficile obtained from fecal samples of wild animals in Brazil
Authors: Lima Maiara C. , Basso Roberta M. , Cerri Fabrício M. , Lima Heloísa C. , Rahal Sheila C. , Zanon Isabela P. , Carvalho Gabriela M. , Silva Rodrigo Otávio S. , Arroyo Luis G. , Oliveira-Filho José P. , Borges Alexandre S.
Published: February 2024

ABSTRACT: Clostridioides difficile is a strictly anaerobic, spore-forming Gram-positive bacterium associated with diarrhea, known as C. difficile infection (CDI). In domestic animals, C. difficile is considered an important pathogen mostly in pigs and horses, but there are also reports in other domestic species. In wild animals, the epidemiology of C. difficile is largely unknown, and the role of the bacterium as a cause of diarrhea is unclear. The aim of this study was to determine the prevalence of C. difficile in the feces of wild animals referred to the Center of Medicine and Research in Wild Animals (CEMPAS). Fecal samples obtained from 100 animals of 34 different species were subjected to qPCR for the detection of the C. difficile 16S rRNA gene and two major toxin genes (tcdA and tcdB) and to anaerobic bacterial isolation. A total of 63 animals (63%) were positive for C. difficile by qPCR, and 16 isolates were recovered. The opossum (Didelphis spp.) had the highest number of positive animals in both tests (from 21 samples, 19 were qPCR positive, and four isolates were recovered). Three toxigenic strains (RT 002, 004, and 014), all previously described as infecting humans and animals, were isolated in the following species: bearded dragon (Pogona vitticeps), pampas fox (Lycalopex vetulus), and marmoset (Callithrix sp.). The presence of C. difficile in the feces of wild animals highlights the importance of wildlife as potential carriers of infection for production animals or humans.
Increasing levels of cornmeal improve chemical and fermentation parameters of maniçoba silage
Authors: Silva Pedro Henrique Ferreira da , Neves Romildo da Silva , Medeiros Geovergue Rodrigues de , Costa José Henrique Souza , Ribeiro Neila Lidiany , Carvalho Chrislanne Barreira de Macêdo , Cavalcante Iara Tamires Rodrigues , Santos Severino Guilherme Caetano Gonçalves dos
Published: February 2024

Abstract Ensiling maniçoba (Manihot pseudoglaziovii) is essential to preserve the nutrients of this forage plant. However, the plant moisture content may generate undesirable fermentations. The objective of this study was to evaluate the effects of different cornmeal inclusion levels (0%, 10%, 20%, and 30%) on the chemical composition and fermentation parameters of maniçoba silage, in addition to identifying the variables most affected by cornmeal. The concentrations of dry matter (DM), non-fiber carbohydrates (NFC), total digestible nutrients (TDN), and propionic acid increased with cornmeal inclusion levels (P < 0.05). Crude protein (CP), lignin, and butyric acid contents, as well as pH, were reduced by the additive (P < 0.05). Principal component analysis resulted in two main groups. Group I was formed by variables positively affected by cornmeal inclusion, namely DM, hemicellulose, NFC, and TDN. Group II contained variables that were negatively affected by cornmeal, namely CP, lignin, mineral matter, and butyric acid. Regardless of the addition of cornmeal, maniçoba silage displays an adequate chemical composition and a good fermentation profile for ruminant feeding. Dry matter and total digestible nutrients are the chemical variables most influenced by cornmeal inclusion, whereas pH and butyric acid are the fermentative parameters most affected by the moisture-absorbent additive. Including moderate levels of cornmeal in maniçoba silage is recommended to achieve the best fermentation profile and the highest concentration of digestible nutrients without mischaracterizing it as a roughage feed.
Aquisição da dependência de gonadotrofinas pelos folículos antrais iniciais e os desafios para promover o seu crescimento in vitro
Authors: Barbalho Efigênia Cordeiro , Nascimento Danisvânia Ripardo , Barrozo Laryssa Gondim , Paulino Laís Raiane Feitosa Melo , Assis Ernando Igo Teixeira de , Silva José Roberto Viana
Published: February 2024

Resumo Esta revisão tem como objetivo discutir os principais fatores envolvidos no desenvolvimento de folículos antrais iniciais até a dependência de gonadotrofinas. Essa fase folicular é caracterizada por intensa proliferação de células da granulosa, formação de uma cavidade preenchida por líquido, diferenciação morfológica das células do cumulus, células da granulosa murais e recrutamento de células da teca. A interação entre oócito, células da granulosa e da teca é determinante para o crescimento folicular e produção hormonal. Fatores de crescimento produzidos pelo oócito, fator de crescimento e diferenciação-9 (GDF-9) e proteína morfogenética óssea-15 (BMP-15), regulam a proliferação e diferenciação de células da granulosa, e o desenvolvimento da cavidade antral, bem como estimulam a produção de receptores do hormônio folículo estimulante (FSH) nas células da granulosa. Em resposta ao FSH, as células da granulosa secretam o peptídeo natriurético tipo C (CNP), que atua através de seu receptor para aumentar a produção de monofosfato de guanosina cíclico (GMPc) e consequentemente o desenvolvimento folicular. As células da granulosa também produzem o fator de crescimento semelhante à insulina 1 (IGF-1) e aumentam a atividade da enzima aromatase, o que resulta em maior sensibilidade às gonadotrofinas e esteroidogênese folicular. A ausência de sinalização do IGF-1 causa cessação do crescimento folicular no início do estágio antral. Muitos outros fatores locais estão envolvidos na regulação do desenvolvimento folicular. Por tanto essa revisão traz dados relevantes para uma melhor compreensão dos mecanismos envolvidos no controle do crescimento de folículos antrais iniciais, enfatizando o papel dos fatores endócrinos e parácrinos, a interação oócito-células da granulosa e os processos de atresia folicular. Os desafios para o estabelecimento de sistemas de cultivo eficientes para o crescimento in vitro de folículos antrais iniciais também são discutidos.
Level of compliance with good manufacturing practices and microbiological profile of mixed fresh sausages
Authors: Charão Gabriel Nunes , Radünz Marjana , Sawitzki Maristela Cortez , Molina Paulo Duran , Gandra Tatiane Valente Kuka , Mello Jozi Fagundes de , Gandra Eliezer Avila
Published: February 2024

Abstract Good manufacturing practices in production facilities are necessary to control microbiological growth and prevent foodborne illnesses. Among the various foods that can be contaminated by intensive handling, meat products such as fresh sausages stand out. With this in mind, the aim of this study was to establish a microbiological profile of the fresh sausages produced in the municipality of Alegrete-RS, Brazil, as part of the SIM/SISBI inspection between 2014 and 2016 and to promote and evaluate the producing establishments in terms of compliance with good manufacturing practices. Samples were regularly taken from 10 businesses in the city and tested for thermotolerant coliform bacteria, sulphitereducing Clostridium, coagulase-positive Staphylococcus and Salmonella spp. In addition, the adequacy of good manufacturing practices was assessed and measures in the form of questionnaires, guidelines and training to improve the production chain were implemented in these companies. Over the years, significant improvements in compliance with good manufacturing practices have been observed in the production units. The microbial count of thermotolerant coliforms, sulphite-reducing Clostridium, coagulase-positive Staphylococcus and Salmonella spp. decreased significantly, indicating that the interventions contributed to improving the microbiological profile of the fresh sausage produced in the community.
Fatores relacionados ao letramento em saúde de adolescentes brasileiros: estudo transversal
Authors: Pimentel Sidiany Mendes , Avila Marla Andréia Garcia de , Medeiros Vinnicius Dias Alves de , Prata Rafaela Aparecida , Nunes Hélio Rubens de Carvalho , Silva Juliana Bastoni da
Published: February 2024

RESUMO Objetivo: Analisar a relação entre fatores sociodemográficos e clínicos com o letramento em saúde de adolescentes brasileiros. Método: Trata-se de um estudo transversal com 526 adolescentes de 14 a 19 anos. Os dados foram coletados virtualmente entre julho e setembro de 2021 por meio de questionário de caracterização sociodemográfica, do perfil clínico e do Health Literacy Assessment Tool – versão em português. As variáveis foram avaliadas por regressão linear múltipla com resposta normal, com significância p < 0,05. Resultados: A média de idade foi de 16,9 anos (±1,6), a pontuação média do letramento em saúde foi de 25,3 (±5,4). Sexo feminino (p = 0,014), maior escolaridade (p = 0,002) e uso de medicamentos (p = 0,020) foram relacionados a maiores níveis de letramento em saúde. Adolescentes com doenças crônicas apresentaram pontuação total do letramento superior, em média 1,51 pontos, comparados aos sem doença crônica. Conclusão: Adolescentes do sexo masculino e os com menor escolaridade apresentaram pior desempenho no letramento em saúde e, por isso, merecem especial atenção nas ações de promoção da saúde.
Padrões espaciais da prematuridade e seus determinantes na região metropolitana de São Paulo, Brasil, 2010-2019
Authors: Rodríguez Elias Carlos Aguirre , Rodríguez Elen Yanina Aguirre , Marins Fernando Augusto Silva , Silva Aneirson Francisco da , Nascimento Luiz Fernando Costa
Published: February 2024

RESUMO Objetivo: Analisar a distribuição espacial dos nascimentos prematuros e sua associação com indicadores maternos, sociais e de serviços de saúde na região metropolitana de São Paulo, Brasil, 2010-2019. Métodos: Estudo ecológico utilizando dados sobre recém-nascidos pré-termo dos 39 municípios da região metropolitana de São Paulo. Utilizou-se o índice de Moran (Im) global univariado para avaliar a associação espacial da prematuridade, e o índice de Moran local univariado por meio do mapa de clusters (LISA) para a identificação de padrões e aglomerados espaciais. Também foi utilizado o índice de Moran global bivariado para analisar a autocorrelação espacial com os indicadores maternos, sociais e de serviços de saúde. Resultados: Foram registrados 3.103.898 nascidos vivos no período 2010-2019, dos quais 331.174 (10,7%) foram prematuros. O índice de Moran global mostrou independência espacial (Im=0,05; p-valor=0,233) da proporção dos nascimentos prematuros entre municípios. No entanto, na análise espacial local foi possível identificar aglomerado espacial estatisticamente significativo entre os municípios de Biritiba Mirim, Guararema e Salesópolis, com proporções altas de nascimentos pré-termo. Na análise bivariada, identificou-se associação espacial significativa positiva com proporções de mães menores de 20 anos (Im=0,17; p-valor=0,024) e mães com baixa escolaridade (Im=0,17; p-valor=0,020), e associação espacial significativa negativa com IDH (Im=-0,14; p-valor=0,039). Conclusão: A abordagem espacial local identificou agrupamento espacial situado no extremo leste da região metropolitana de São Paulo, onde ações dos gestores de saúde são necessárias para minimizar a ocorrência de partos prematuros.
The educational policy of the new Brazilian Common National Curriculum Framework: an Analysis based on Biopolitics
Authors: Trevisan Amarildo Luiz
Published: February 2024

Abstract This article discusses the educational policy of the new Brazilian National Curricular Common Base (NCCB-BNCC) in the epistemological context of biopolitics. It brings together international authors and works that contribute to elucidate elements of this context, such as the concepts of "life" and "death," "citizenship," and "bare life." The text presents the criticisms of some Brazilian educators on the subject, focusing primarily on Dermeval Saviani's diagnosis, one of the important references in the field of Brazilian educational policy. It concludes that such concepts can shed new light on the subject, demonstrating the fragility of this educational policy that, by being exclusively guided by biopolitical criteria, excludes a broader and civic education.
Sínteses da apropriação do conceito de Educação Estética de Vigotski no Ensino de Arte brasileiro (2006-2020)
Authors: Almeida Marilene Oliveira , Barros Gelka Arruda de , Campos Regina Helena de Freitas , Araújo Christiane Campos de , Cañete Lilian Sipoli Carneiro
Published: February 2024

Resumo A teoria histórico-cultural, criada pelos pesquisadores russos Vigotski, Leontiev e Luria entre 1920 e 1930, alcança os pesquisadores de Psicologia e Educação no Brasil a partir de 1980, apresentando uma nova dimensão para a formação e atuação desses profissionais. Com base nesse pressuposto, realizou-se revisão sistemática da literatura científica brasileira entre 2006-2020 em busca de artigos publicados em áreas de interseção entre a Psicologia da Educação e a Arte Educação, visando a identificar a circulação, recepção e apropriação do conceito de educação estética de Vigotski. Os resultados encontrados coadunam com estudos de teóricos que consideram os conceitos de “vivência” e “meio” como essenciais para a compreensão da teoria histórico-cultural.
Os efeitos de Maio de 68 na trajetória de Jacques Rancière: a dicotomia althusseriana entre ciência e ideologia colocada em xeque
Authors: Araújo Taís
Published: February 2024

Resumo Após Maio de 68, a dicotomia entre um conhecimento científico e a ideologia, tal como sustentavam os althusserianos, é colocada em xeque em favor de uma valorização dos movimentos políticos irruptivos dos anos 1960, por Jacques Rancière. No presente artigo, analisaremos esse momento de sua trajetória, em que o autor reformula sua compreensão a respeito do significado das revoltas políticas e de sua concepção sobre o saber. Esse debate não é algo circunstancial na obra de Rancière, antes aparece como uma questão que atravessa seu pensamento e contempla ainda seus escritos atuais: a recusa à divisão do saber, suas hierarquias intelectuais e a desconfiança em relação à concepção de que a política necessitaria da teoria como pré-requisito.
Retrato da inserção de terapeutas ocupacionais no Sistema Único de Assistência Social
Authors: Basso Ana Carolina de Souza , Homem Janette dos Santos , Borba Patrícia Leme de Oliveira
Published: February 2024

Resumo Introdução Desde 2005, as cidades brasileiras estão se adequando para organizar equipes e serviços do Sistema Único de Assistência Social (SUAS) e, a partir de 2011, a terapia ocupacional passou a ser reconhecida como uma das profissões que compõem tais equipes e a gestão do SUAS. Este estudo aborda como a categoria tem participado dessa política no estado do Rio de Janeiro. Objetivo Mapear as terapeutas ocupacionais que atuam no SUAS nesse estado e delinear as características dessa inserção. Metodologia Estudo de mapeamento, descritivo e transversal, utilizando informações oficiais do Censo SUAS. Os dados foram analisados a partir de uma perspectiva descritiva, em diálogo com a Política Nacional de Assistência Social, a literatura do campo da terapia ocupacional na assistência social e sob o referencial da terapia ocupacional social. Resultados No estado do Rio de Janeiro, 142 terapeutas ocupacionais atuam no SUAS, o equivalente a 8,9% das profissionais desse estado. Como retrato, obtivemos imagem formada por mulheres (89,4%) entre 41-50 anos de idade (34,5%), contratadas por Organizações da Sociedade Civil (93%), celetistas (50%), com carga horária semanal de 11-20 horas (40,9%), inseridas majoritariamente nos Centros-dia (71%), atuando com pessoas com deficiências e idosas. Conclusão A inserção de terapeutas ocupacionais no SUAS fluminense acontece de forma precarizada, com baixa inserção nos equipamentos estatais. Sinaliza-se a necessidade de as entidades representativas da classe atuarem nessa política pública enquanto promotora de ampliação de vagas/concursos/emprego, bem como investirem em debates sobre as composições das equipes e o reconhecimento dos diferentes campos de saber.
ENTRE LITERATURA E EDUCAÇÃO: AS TRAJETÓRIAS INTERTEXTUAIS DAS ESCRITORAS LINDANOR CELINA E MARIA LÚCIA MEDEIROS
Authors: Alves Laura Maria Silva Araújo , Conceição Lília Batista da , Nery Guthemberg Felipe Martins
Published: February 2024

RESUMO O presente artigo traz uma análise dialógica intertextual da trajetória de vida, da obra e do pensamento das professoras e escritoras bragantinas Lindanor Celina e Maria Lúcia Medeiros. Ambas estrearam na literatura da Amazônia paraense com prosas ficcionais dando destaque às personagens femininas transgressoras e insubmissas. São seus livros: Estradas do tempo-foi (1971) e o romance Menina que vem de Itaiara (1996), de Lindanor Celina, e a coletânea de contos Zeus ou a menina e os óculos (1988), de Maria Lúcia Medeiros. Em termos metodológicos, esta pesquisa é de abordagem qualitativa, do tipo documental. Assim, entende-se que há aproximação intertextual nas trajetórias de educação, formação feminina e infância das referidas escritoras.
FORMACIÓN INICIAL DE LAS DOCENTES Y LOS DOCENTES Y BIOGRAFÍAS DE MUJERES EN LIBROS ILUSTRADOS DE NO FICCIÓN
Authors: Claudio Carmen Romero , Ponce Hugo Heredia , Oliva Manuel Francisco Romero
Published: February 2024

RESUMEN Esta investigación pretende incidir en la formación inicial para una “Igualdad de género” (ODS 5) a partir de libros ilustrados de no ficción (LINF) y biografías femeninas. Se encuadra en el paradigma cualitativo, una investigación educativa participativa en el grado en Educación Primaria, Universidad de Cádiz (España). Los LINF de biografías se convierten en la base para la promoción de la lectura y el reconocimiento de la mujer desde la justicia social, educativa y curricular. Los resultados y conclusiones se proyectan en dos cartografías de LINF que abogan por la igualdad y su visibilización.
GOVERNED ON THEIR OWN TERMS: FANS’ PROSUMPTION OF AVENGERS ENDGAME MEDIA PARATEXTS
Authors: Moura Bruno Melo , Souza-Leão André Luiz Maranhão de
Published: February 2024

ABSTRACT Based on the Foucauldian framework, this research aims to analyze how fans’ prosumption of media products’ paratext reveals consumers’ governmentality. The Netnographic Foucauldian Genealogy was adopted to analyze the fans’ interaction with media paratexts of the movie Avengers: Endgame. Results show that fans’ opinions ranged from acknowledging the quality of paratexts to feeling disappointed with them. Thus, it is possible to state that fans allow themselves to be governed by the entertainment industry to safeguard their fan condition.
A construção de um improvável herói esportivo: o capoeira Cyriaco (1909-1925)
Authors: Silva Marcelo Moraes e
Published: February 2024

Resumo: Uma das características mais marcantes do esporte moderno é a capacidade de transformar alguns atletas em heróis. Trata-se de um fenômeno no qual os meios de comunicação desempenham um papel fundamental na construção de uma aura mítica em torno de determinados esportistas. Sendo assim, o presente artigo busca analisar como a imprensa escrita brasileira elaborou a imagem heroica em torno da figura do capoeira Cyriaco, brasileiro que, em maio de 1909, se tornou famoso por derrotar um japonês praticante de jiu-jitsu até então apontado como invencível. As fontes selecionadas para alcançar tal intento foram localizadas na imprensa escrita, entre os anos de 1909 a 1925. Como conclusão aponta-se que Cyriaco foi um dos primeiros heróis esportivos brasileiros oriundo das classes populares alçado a um símbolo da nascente república, que carecia de ídolos que fossem identificados com a emergente nação mestiça
The engineering legacy of the FIFA World Cup Qatar 2022: Al Janoub stadium
Authors: Leach Jon , Sparrow Craig , Iori Federico , Al-Nuaimi Hamad N. , Elshafie Mohammed Z. E. B. , Al-Nuaimi Nasser A.
Published: February 2024

Al Janoub was the first new-build stadium designed for the FIFA World Cup Qatar 2022. This paper describes the journey of the engineering design of the 40 000 seat stadium, from the concept and detailed design development stages led by AECOM and Zaha Hadid Architects, through to the design and build contract on site. An architectural jewel located in Al Wakrah, just south of the city of Doha, the stadium was a world-first, using state-of-the-art computational analysis and physical modelling to create a safe, cooled environment that satisfies FIFA's requirements for both player and spectator comfort in the extreme temperatures of the region. A sustainable post-tournament legacy was also a key factor of the design, allowing it to be reduced to a 20 000-capacity stadium for the local football club and community. The task of integrating the stadium's stringent performance requirements on this path-finder project, including extensive scientific research and development, was a challenge that was overcome through close collaboration between the design team and the Supreme Committee's subject matter experts. The project's success as a test-bed helped it to set the standard for other stadia as part of the overall FIFA World Cup Qatar 2022 programme.
Construyendo Juntos: un programa de tamizaje en salud mental para la inclusión social
Authors:   Universidad Cooperativa de Colombia, Munera Luque Kenia , Miranda Sánchez Zullys , Sánchez Pabón Dalgis , Rodríguez Vega Óscar
Published: February 2024

Se llevó a cabo un estudio transversal analítico, con el objetivo de implementar un tamizaje en salud mental. La muestra estuvo constituida por 147 sujetos pertenecientes a una comunidad de viviendas de interés prioritario. Los instrumentos de evaluación utilizados fueron el Apgar familiar, una escala de datos sociodemográficos y el Self Reporting Questionnaire (SRQ). Se encontró que un gran porcentaje de los participantes no han culminado sus estudios básicos, que el 54,4% presenta algún nivel de disfuncionalidad familiar y que las sintomatologías con mayor frecuencia fueron depresión y angustia. Estos hallazgos resaltan la importancia de la implementación de estrategias orientadas a la atención primaria en salud.
Analysis of Türkiye's Cybersecurity Strategies: Historical Developments, Scope, Content and Objectives
Authors: ÇİFCİ Hasan
Published: February 2024

Cybersecurity is regarded as a crucial part of overall national security. A national cybersecurity strategy (NCSS) offers direction and a framework for national cybersecurity-related concerns and initiatives. Many nations have devised their own plans to defend against attacks, reduce risks, discourage attackers, and provide a secure and accessible cyberspace to promote innovation, the economy, commerce, and wealth. In order to assist the countries in developing their plans, organizations like the ITU, ENISA, OECD, NATO, e-Governance Academy and Oxford University issued research and advice publications based on the best practices from various countries. The assessment of the scope, objective, and content of Turkish national cybersecurity strategies is limited in academic literature. The studies in the literature that gathered multinational NCSS attributes from various countries and served as a guide for the development of national cybersecurity strategies were examined through a comprehensive literature review in order to assess Türkiye's strategies in terms of scope, content, and objectives. Following the development of assessment criteria based on these studies and research, a qualitative study was carried out to evaluate and ascertain the degree of conformity of Turkish cybersecurity strategies with the criteria. The historical context of Türkiye's cybersecurity strategies was explored in this article, along with strategy revisions, evaluations of the strategies' scope, content, and objectives, and gaps that should be filled to make the strategies more effective.
Application and Performance Evaluation of Chemical Coagulation, Electrocoagulation, Electro-Fenton and Anodic Oxidation Processes in the Treatment of Glass Fiber Manufacturing Wastewater
Authors: KAR Buket , GÖRMEZ Özkan , GOZMEN Belgin
Published: February 2024

This study investigated the oxidation of wastewater generated during the production of glass fiber manufacturing material, which contains high organic carbon (18.32 g/L) and has a pH of 8.8, by chemical coagulation, electrocoagulation and electro-advanced oxidation techniques. It was determined that the total organic content (TOC) of wastewater was reduced by 53% using the chemical coagulation method. After electrocoagulation with Al/Al electrode pair for 300 minutes at 500 mA, 73% TOC removal was achieved at pH 8.8. While 50% TOC removal was completed in 2 h at 400 mA in electrocoagulation with Fe/Fe electrode pair, 71% TOC removal was obtained in the combined electrocoagulation/electro-Fenton process by adding hydrogen peroxide to the medium under the same conditions. In addition, it was also observed that the success of the anodic oxidation methods alone was lower. The electro-Fenton application after electrocoagulation was effective and provided 78% TOC but required work at pH 3 and a longer treatment time.
Ameliorative Effect of a Vanadium-thiosemicarbazone Complex on Oxidative Stress in Stomach Tissue of Experimental Diabetic Rats
Authors: KARAKUŞ Fatma Gülnaz , TUNALI Sevim , BAL-DEMİRCİ Tülay , ÜLKÜSEVEN Bahri , YANARDAĞ Refiye
Published: February 2024

Recently, we have shown that oral administrations of an oxidovanadium (IV) complex, VOL, with tetradentate thiosemicarbazone ligand normalizes hyperglycemia of streptozotocin-induced diabetic rats (STZ-rats). For the development of vanadium compounds that exhibit insulin-like behavior, it is essential to know some of the pharmacokinetic properties of these complexes. The goal of the current research is to examine the healing effect of new sythesed VOL complex on the oxidative stress parameters of diabetic stomac tissue. Rats used in the experiments were divided as control, VOL+control, diabetic and diabetic+VOL. The rats were sacrificed after 12 days of the experimental period. The levels of glutathione, lipid peroxidation, non-enzymatic glycosylation, advanced oxidized protein products levels and the activities of some enzymes were measured in stomach tissue of all the experimental animals. Although VOL treatment to diabetic rats increased the stomach glutathione levels; lipid peroxidation, non-enzymatic glycosylation and advanced oxidized protein products levels were decreased. Also, the activities of catalase, superoxide dismutase, glutathione-S-transferase, glutathione peroxidase, glutathione reductase and carbonic anhydrase were increased in VOL treated diabetic group. Whereas, lactate dehydrogenase and xanthine oxidase activities were decreased. According to the obtained outcomes, it can be said that VOL treatment has a healing effect on the stomach tissue of diabetic rats. This effect provided by VOL is most likely due to the insulin-like and antioxidant activity of the complex. In conclusion, we can say that VOL may be a suitable candidate for diabetes treatment.
Drag Reduction on Microstructure Surfaces
Authors: KODAL Ahmet İlyas , KAPKIN Şule , GÜVEN Hasan Rıza
Published: February 2024

In this study, experimental work in the literature about friction on bird-feather like structures has been reviewed and one of these was modeled by using CFD (Computational Fluid Dynamics) to obtain minimum grid parameters. Coupled with obtained optimal grid parameters, the shear stresses of the two-dimensional models were investigated at the values of Reynolds number 110,000-470,000. Based on the concluded previous study, three-dimensional geometries were modeled with reference to two-dimensional models and analyzed with the determined grid structure. The results of the analysis are compared with those of the previous experimental study in the literature. In the final phase of the study, a drag reduction was found to be approximately 30% on the surfaces inspired by bird feathers.
Distributed Control of a Vibrating String in Response to Pointwise Force Application
Authors: KAPKIN Şule , DEMİR Mehmet Şirin , UZAL Erol
Published: February 2024

The problem of controlling the vibrations of a string by a discrete applied force is considered. The vibrations of the string are modeled by the linear wave equation and the control is provided by an added force term. The wave equation is solved for controlled and uncontrolled cases with and without control force term. The applied force is chosen to be proportional to string displacement at some specified point. In the controlled case; the wave equation involves a control parameter (gain) and related terms involving the value of the displcement at a single point and a delta function. This makes the equation quite different from the usual wave equation. The problem is solved analytically using a modified (compared to usual wave equation) solution procedure and an equation relating the string eigenfrequencies to the proportionality constant (gain) is derived. This allows the observation of the change in eigenfrequencies with the gain. Finally, examples of uncontrolled and controlled responses are presented, graphically. The results show that the resonances can be avoided by the applied control procedure.
Effect of Sampling Orientation on The Mechanical Properties of Glass Fiber Reinforced Epoxy Nanocomposites
Authors: DEMİRCAN Gökhan
Published: February 2024

Fiber-reinforced polymer composites are manufactured using various methods, with vacuum-assisted resin transfer molding (VARTM or VARIM). This study's primary focus lies in assessing how the orientation of sampling impacts the mechanical properties of glass fiber-reinforced pure and nanocomposites. 2 wt.% nano Al2O3-doped and non-doped composites were produced using the VARTM process. Tensile, flexural, and density test specimens were extracted from three distinct zones and two distinc direction those aligned horizontally to the resin flow (HRF) and those oriented vertically to the resin flow (VRF). Remarkably, results showed up to a 3.91% increase in values from samples in the third zone, particularly on the vacuum outlet side. To facilitate precise stress value comparisons across plates, uniform sample orientation and consistent zone selection are essential.
A Rapid DMeyer-CWT Method Application to the Spectrophotometric Data for the Quantification of Losartan Potassium and Hydrochlorothiazide in a Binary Mixture
Authors: ÜSTÜNDAĞ Özgür , DİNÇ Erdal
Published: February 2024

This paper outlines a precise, swift, and convenient spectrophotometric method based on the continuous wavelet transform methodology for the estimation of losartan potassium and hydrochlorothiazide in tablets. The continuous wavelet transform method is based on the use of DMeyer (DMEY-CWT). When the original UV spectra of losartan potassium and hydrochlorothiazide are studied, it is clear that their spectra closely overlap. The analysis was completed successfully without any pre-separation using the created DMEY-CWT approach. The calibration equations for losartan potassium measurement and hydrochlorothiazide determination were obtained at 257.6 nm and 268.4 nm for losartan potassium, 250.1 nm and 263.8 nm for hydrochlorothiazide. The developed approaches were evaluated for their validity and practicality.
RESEARCH OF THE METHODS OF TEACHING LITERARY READING IN ELEMENTARY SCHOOL
Authors:   Jalal-Abad State University, Sakieva Sayipzhamal , Osmonalieva Sabira ,   Jalal-Abad State University
Published: February 2024

The content of the article is devoted to the work of the famous scientist Sultan Turusbekov on the development of oral and written speech of students in grades 1-4. The article presents an in-depth analysis of research models for the development of oral and written speech in primary school children. The forms and methods of development of oral and written speech were assessed by the author as the initial stage of work. The scientist also developed ways and methods of enriching the vocabulary work of younger students. Practical developments in the development of speech and vocabulary have been developed in depth.
LITERARY ANALYSIS OF THE LYRICAL SONG “MONUMENT” BY TOLOGON MAMEEV
Authors:   Osh State University, Koldoshov Tumonbai , Yzabekova Dinara ,   Osh State University, Kalmatova Venera ,   Osh State University
Published: February 2024

This article is discussing a literary analysis of the lyrical song by Tologon Mameyev “Monument”. Although many songs dedicated to the poetry of war, a smaller number of them with music. The song from the period of war and still famous nowadays chosen here for analysis. The inner content of the song, author idea, structure of the song, and difficulties in war have been discussed. Poet was able to articulate the impact of the whole war catastrophe through the inner lyrical content. Literary text created from the thoughts of the poet, after the creation of the melody, became more audible, more influential, and more popular. A picture is representing the tragedy of the war with a lyrical retreat, remembering the soldiers who went to the front and did not return, evaluates patriotic citizens from different angles, and urges them to remember their memory forever. The writing years of song “Monument” by the famous poet and its influence, expressions in the text, artistic metaphors, typical images, stylistic features, and lyrical reflections are scientifically analyzed.
FORMATION OF THE SATIRE GENRE IN THE WORLD LITERATURE
Authors:   Bishkek Humanities University named after K. Karasaev, Ormonova Sabira
Published: February 2024

In this article, the author provides an overview of the origin of the genre of satire and humor in literature. Satire as a lyric-epic genre which was originated in the literature of Ancient Rome. In ancient Greek literature, the origin of satire dates back to the II- millennium BC. The development of satire in the Middle Ages continued in the literature of the countries of the East and Europe. In the literature of Western Europe during the Middle Ages, satirical elements can be found in the songs of the Vagant folk poets. 16-17th centuries satirical elements acquire a prosaic and open poetic journalistic nature and are widely disseminated in the writings of writers, working in the directions of romanticism, realism and modernism. In 17-18 centuries in England confrontation between two political parties - Tories and Whigs contributed to the development of the satire genre. 19th century magazine satire tends to feuilleton and contributes to the widespread use of satire in novels and dramas. XX century in the development of Russian satire, the release of magazines plays an important role "Satyricon" (1908-1914), "New Satyricon" (1913-1918).
Fruit and seed morphometry and seed structure of the potentially invasive Calotropis procera (Aiton) W.T. Aiton (Apocynaceae)
Authors: Navarrete-Sauza Emiliano , Rojas-Aréchiga Mariana , Pérez-Pacheco Mónica Karina , Márquez-Guzmán Judith
Published: February 2024

Background: Calotropis procera is a plant native in the tropics and subtropics of Asia and Africa. In Mexico, its presence is now registered in Yucatán, Quintana Roo and Oaxaca. Questions and / or Hypotheses: Fruit and seed morphometry vary among places where it is native or exotic? Are seed structures well identified in Calotropis procera? Studied species: The exotic Calotropis procera has been already reported in several states in Mexico, however, information about its reproductive biology in Mexican populations is scarce.   Studied site and dates: Fruits were collected in Oaxaca, Mexico in September 2019. Methods: We obtained fruit and seed morphometric data and seed images with microscopy. Results: The fruits are green and ovoid. The average number of seeds per fruit is 364 ± 86 (SD). The seed is brown and flattened dorsoventrally. The length of the seeds is 8.37 ± 0.413 mm, the width is 5.01 ± 0.39 mm, and the weight is 10.5 ± 7.86 mg. The position of the hilum and the micropyle is reported and the occurrence of two types of trichomes on the testa. We suggest that the protrusion on the ventral surface of the seed is the raphe. Conclusions: From data obtained we concluded that fruit and seed characteristics are well conserved in this species. We confirmed the position of the hilum and micropyle and reported the presence of two types of trichomes in the testa. Location of the raphe is suggested, providing information that may be useful for future taxonomic studies.
Parallels and challenges between municipal policies and international guidelines for early childhood
Authors: Pessoni Isabela Grilo , Marino Cintia de Castro , Silva Thaísa Leal da , Levy Wilson
Published: February 2024

This paper aims to explore parallels and challenges between municipal policies and international guidelines focused on early childhood, directing its attention towards the development of a comparative analysis. In this regard, the construction of an analytical framework that establishes relationships between the Municipal Plan for Early Childhood of the Municipality of São Paulo (2018-2030) and the global initiative Urban95 by the Bernard Van Leer Foundation guidelines, which addresses the inclusion of the child's perspective in cities. The exploratory research method used involves public administration reports examination, including the plan and its annual assessments. During the research process, key information was extracted focusing on the identification of laws, regulations, action plans, and projects aimed at advancing early childhood care, with the aim of validating and expanding the understanding of the subject. In a context where cities must provide conducive environments for child development, the study seeks to understand how municipal policies align with international guidelines. The results highlight the advances and challenges resulting from inequalities in the city of São Paulo in the scope of attention to early childhood, emphasizing the need for coordinated and interdisciplinary public policies in this agenda.
SOP for DSS kinetics studies v1
Authors: G Tansey Malu
Published: February 2024

SOP for DSS kinetics studies
Querying for Bacterial Pathogen Genomic Data at NCBI v1
Authors: Balkey Maria , Timme Ruth , Lusk Pfefer Tina , Hope Bias Candace
Published: February 2024

PURPOSE: This document provides detailed instructions on how to find bacterial pathogen genomic data and associated contextual information at NCBI, specifically at the BioSample, SRA, and Pathogen Detection databases. SCOPE: This protocol is intended for use by any laboratory submitting WGS data of bacterial pathogens to NCBI for analysis within NCBI Pathogen Detection. This includes US labs connected to GenomeTrakr, NARMS, Vet-LIRN, NAHLN, and other international networks and submitters.
Extract-N-Amp Equivalent DNA Extraction Protocol v2
Authors: Douglas Russell Stephen
Published: February 2024

This extraction protocol uses an Extract-N-Amp equivalent solution to quickly and cheaply perform DNA extractions. This protocol has been widely used for dried specimens of macrofungi, but will work for other organismal groups as well. This protocol is an amalgamation of two different protocols that are currently in use by academic labs in the United States. This protocol is easily scalable for larger batch sizes. The standard protocol assumes 100mL batches. This is enough extraction solution for 5,000 specimens. The primary thing needed to scale up are larger sizes of the sterile vacuum filter flasks. They come in each size you may need - 250mL, 500mL, or 1000mL. For larger batch considerations: 100mL is enough for ~5,000 extractions 250mL is enough for ~12,500 extractions 500mL is enough for ~25,000 extractions 1000mL is enough for ~50,000 extractions
Synthesis of Carbon Dots using Citric acid (Solvent Free reaction) v1
Authors: not provided qurashiubaid
Published: February 2024

Carbon Dots are the fluorescent nanoparticles that have wide range of applications. Facile synthesis of Carbon Dots paves the way for making this material mainstream for use. Synthesis of Carbon Dots by using Citric acid as the precursor in a solvent free reaction is a easy method in which the synthesized Carbon Dots shows fluorescence in the range of 520nm. This mode is simple and doesn't require complex instrumentation.
SOP FOR MESOSCALE DISCOVERY ASSAYS v1
Authors: G Tansey Malu
Published: February 2024

SOP FOR MESOSCALE DISCOVERY ASSAYS
Social Media Marketing and Fashion Purchase Intention in Indonesia's Transitional Economy
Authors: Atrisia Marchela Indah , Syafawi Lely , Sari Nurmalla
Published: February 2024

The research set out to look at how social media marketing in the fashion business in Indonesia, a developing nation, affects consumers' propensity to make a purchase. This study surveyed 118 people in Indonesia using an online survey instrument. The proposed theoretical model was tested using Smart PLS and structural equation modeling (SEM). The bootstrapping method was used to test the hypotheses and the mediating roles of brand awareness and customer satisfaction. Despite the direct influence of social media marketing on purchase intention, brand awareness and customer satisfaction do not mediate the relationship between the two. This study contributes to the literature by shedding light on the impact of social media marketing on brand awareness, customer satisfaction, and purchase intention in transition economies, such as Indonesia. Findings from this study have practical applications because they can help marketers in a variety of contexts design social media marketing strategies that are more likely to be successful in reaching their intended audiences despite economic uncertainty.
Optimalisasi Pemetaan Bisnis Menggunakan Triple Layer Business Model Canvas
Authors: Adib Mokh , Suryana Suryana , Wijaya Fanji
Published: February 2024

Vocational High School as a center of excellence is a solution to increase the business productivity of the school. This study aims to find out the business strategies that have been carried out by schools using the Triple Layer Business Model Canvas (TLBMC) as a tool to explore business model innovations that are oriented towards. Descriptive research method using an approach based on the philosophy of post positivism, purposive, and snowball sampling from the principal, 5 teacher representatives and 5 student representatives at SMK PK Al Ikhlas Susuru Panawangan which is used as a reference source in finding information to start a business strategy. From the results of the study, it was concluded that based on the TLBMC mapping, the economic strata were well described, the use of unfriendly packaging had an impact on not describing the final element of life, and the extent to which the business carried out did not cause negative social impacts. The PMIA score shows a positive value, meaning that the business is appropriate and feasible to continue.
A Survey of Banks in Ghana's Credit Risk Management Practices
Authors: Dabi Rowland Seyram Koku , Nugraha Nugraha , Disman Disman , Sari Maya
Published: February 2024

In recent times, banks and other financial institutions that lend money to customers have placed a high priority on credit risk management. To manage credit risk, banks employ customer evaluation systems, loan size restrictions, credit checks, flexible loan repayment plans, and fines Hence, the present study focuses on  the credit risk management practices used in banks, to identify the internal control measures used in mitigating  credit risk in banks and to examine the challenges faced in implementing credit risk management practices. The Ordinal Logistic Regression(OLR) was used to identify the relationships between the response variables, e.g. management support, credit risk identification, internal control measuers and credit risk management surveys. The independent variables were calculated on an ordered, 5-point Linear scale for the responding participants. In this study,  log lit function was chosen, that demonstrated the model appropriateness. One of the main finding is that in banks, credit management risk is reduced when managers implement and adhere to responsible credit risk management procedures, viable client appraisal credit management system, regular credit checks, flexible credit repayment systems to encourage and improve loan repayment, were highly significant with the respondents’ positive initiative amidst credit risk management practices in banks.
Analisis Kompetensi dan Budaya Kerja terhadap Kinerja Di Era Reformasi 4.0
Authors: Panggabean Romli Jumpai , Ahman Eeng , Disman Disman , Rofaida Rofi
Published: February 2024

The purpose of this research to determine the effect of competency and work culture on employee performance in the reform era 4.0 at Bank Sahabat Sampoerna Operational Division. The method in this research is quantitative descriptive through multiple linear regression analysis with the help of the SPSS version 26 program. The results show that competency partially has a positive and significant effect on employee performance, work culture partially has a positive and significant effect on employee performance, competency and work culture simultaneously have a positive and significant effect on employee performance. The implication of these findings suggests that investing in enhancing employee competencies and fostering a conducive work culture can lead to improved performance within the Bank Sahabat Sampoerna Operational Division. Moreover, the simultaneous positive effects of competency and work culture highlight the importance of addressing both factors in the reform era 4.0 to maximize employee performance effectively.
Strategi Pemasaran Digital dalam Mendorong Keputusan Pembelian Produk Olahan Pisang di Indonesia
Authors: Zainudin Muhamad , Maulidah Silvana , Riana Fitria Dina
Published: February 2024

The growth of banana production in East Java faces online marketing challenges and stagnant production capacity. CV. Haza Food Indonesia needs to improve its digital marketing strategy and production efficiency as well as build consumer trust to expand the market and have a positive impact on the local economy. This research aims to explore steps to increase company production capacity, through digital marketing on purchasing decisions for processed banana products in Indonesia. Using SmartPLS 4, 201 potential consumers participated via an online questionnaire. The research results show a significant relationship between social media and purchasing decisions, as well as between eWOM and purchasing decisions. Social media also influences purchasing decisions through eWOM. These findings are consistent with previous research on the positive influence of social media and eWOM on purchasing decisions. These findings provide strategic insight for companies in optimizing digital marketing of processed banana products in the Indonesian market.