bluuebunny/crossref_metadata_2025 huggingface dataset:
An investigation of design management applications in the textiles and apparel industries
Authors: Sanad Reham Abdelbaset
Published: June 2023

This study is concerned with identifying and classifying the design management research approaches and concepts focusing on the textiles and clothing industries. This is to illustrate areas of study that textile design researchers have addressed. Three primary levels of design management were the basis of this study, namely, strategic, tactical, and operational levels. The approach and methodology adopted in several research studies were reviewed and then classification was carried out. It was found that strategic-level studies focused on consumers’ needs, preferences, perceptions, and collection of design information. The tactical/processes level reflected areas of staff development, and the creation of tools, systems, and frameworks employed in production stages. Developing knowledge systems resources and mass customization to meet consumer needs were highlighted in these research studies. At the operational/implementation level, research studies were focused on actions conducted in day-to-day operations such as chemical and physical techniques used in manufacturing processes and quality control.
Keywords: Apparel, consumer, design, management, strategic, tactical, textiles;
Cineforos y educación intercultural
Authors: Vega Angie
Published: June 2023

El presente artículo tiene como objetivo destacar al cineforo como una herramienta pedagógica para la educación intercultural en contextos escolares. Este trabajo busca exponer los hallazgos y beneficios prácticos del cineforo, al analizar películas que abordan problemáticas de discriminación y fomentan el desarrollo de capacidades críticas en los estudiantes. Como instrumento de recolección de información, el análisis de contenido posibilitó la selección de tres películas con componentes históricos y etnoculturales relevantes al tema de la discriminación. Estas películas sirvieron como base para desarrollar tres ciclos de cineforo que, junto con observación participante, permitieron recolectar datos que dan cuenta de prejuicios y estereotipos, además de evidenciar la gran influencia del contexto familiar y cultural en las percepciones de los estudiantes, lo que representa la oportunidad de trabajar una educación centrada en valores como el respeto, la tolerancia y la democracia que incentiven la creación de un espacio de diálogo intercultural, reflexión y movilización de emociones. En definitiva, el cineforo se presenta como una herramienta valiosa para abordar problemáticas complejas, como la discriminación, y fomentar la formación de ciudadanos críticos y comprometidos.
Rupture of the Left Ventricle in the Atrioventricular Groove After Mitral Valve Replacement: A Case Report
Authors: Menon Tushar
Published: June 2023

As we grow older, and our population continues to live longer due to advancements in modern medical therapies, we have a growing population of elderly patients. There will inevitably be more patients who present with mitral stenosis secondary to severe mitral annular calcification and a corresponding need for repair due to the nature of increased friable myocardium present within these tissues. Atrioventricular dissociation associated with left ventricular rupture after mitral valve replacement occurs in approximately 1.2% of cases, and of those cases there is up to a 75% mortality rate even when appropriate surgical techniques are performed [1].
Technology and Tax: Adoption and Impacts of E-services in Rwanda
Authors: Megersa Kelbesa , Santoro Fabrizio , Lees Adrienne , Carreras Marco , Mukamana Theonille , Hakizimana Naphtal , Nsengiyumva Yves
Published: June 2023

Many low-income countries are increasingly digitising their tax services, which can bring a range of benefits, from reducing compliance costs and improving record-keeping, to limiting opportunities for corruption and increasing fairness in the tax system. However, the success of these benefits depends on adequate levels of awareness and adoption of e-services among taxpayers; where these levels are suboptimal, tax e-services may produce only partial benefits. This paper examines the extent of awareness and uptake of tax e-services in Rwanda from a pre-pandemic situation up to two years into the COVID-19 crisis. The country has increasingly digitalised its tax administration, even more so during the pandemic. Electronic filing and payment of taxes have been mandatory since 2015, and two different e-services are available: E-tax, a free web-based platform designed to be used on computers and smartphones, and M-declaration, a feature phone-based application which enables mobile money payments and a simpler process for filing a return. This allows us to run a comparative analysis of the two solutions. We apply a mixed methods approach, using a nationally representative panel survey of 2,000 corporate (CIT) and personal (PIT) income taxpayers, with baseline information collected pre-COVID-19 and four follow-up rounds carried out after the pandemic hit, and focus group discussions (FGDs) with 24 e-services users. Summary of Working Paper 153.
Abordagem da espiritualidade na formação em saúde à luz da teoria de Viktor Frankl
Authors: Biondo Chrisne Santana , Cafezeiro Amanda Sales , Cunha Ana Lúcia Goncalves de Oliveira , Bromochenkel Cattiúscia Batista , Dos Anjos Neta Maria Madalena Souza , Yarid Sérgio Donha
Published: June 2023

Objetivo: refletir sobre a importância de agregar a espiritualidade na formação dos profissionais de saúde por meio dos aspectos basilares da teoria de Viktor Frankl. Método: trata-se de uma reflexão teórica a partir de Viktor Frankl, discutindo sobre a importância de agregar a espiritualidade na formação dos profissionais de saúde. Resultados: Frankl propõe que o homem é um ser dotado de valores criativos, vivenciais e atitudinais, os quais implicam em processos de devoção dos indivíduos a algo maior que si, especialmente, pela superação das adversidades da vida por meio da conquista de um sentido maior. A espiritualidade é característica central dessa visão, conferindo a autotranscedência, ficando claro a importância de inserir essa dimensão na formação em saúde. Conclusão: A importância de organizar a formação dos profissionais de saúde a partir da inclusão da espiritualidade, segundo os postulados teóricos de Frankl, decorre da necessidade de ir além dos estudos disciplinares e fragmentados das graduações, promovendo uma formação humana e integrativa, que inclua reflexões acerca da própria espiritualidade do profissional, bem como daqueles aos quais este assiste
A téchne aristotélica e sua implicação para a enfermagem
Authors: Guimarães Gilberto de Lima , Goveia Vania Regina , Mendoza Isabel Yovana Quispe , Corrêa Allana dos Reis , Guimarães Mariana Oliveira , Silva Silmar Maria
Published: June 2023

Objetivo: Analisar a téchne aristotélica e sua implicação para o cuidado de enfermagem. Metodologia: Texto reflexivo regido pela questão: como a filosofia aristotélica pode implicar o cuidado de enfermagem? Para resposta estabelecem-se os principais elementos que fundam a filosofia de Aristóteles no livro II da Física e na obra Metafísica; e as noções que essa filosofia projeta sobre a ciência e a arte da enfermagem. Resultados: A arte da profissão se manifesta na prática assistencial, na pesquisa e no ensino pelo cuidado de enfermagem. Conclusão: O cuidado de enfermagem é conjugação entre o saber-pensar, saber-fazer e o saber-conviver expresso na téchne da profissão; engloba habilidades manuais, capacidade de inovação, agir humano perante o paciente, organização, gerenciamento de pessoas e unidades; ele medeia o encontro científico e dialógico, marcado pelo senso estético, com o paciente. No sistema aristotélico, epistéme, práxis e a poiésis estão em relação indissolúvel.
Incidência e eventos adversos da hipodermóclise no idoso em cuidados paliativos
Authors: De Souza Raquel Eustaquia , Mendoza Isabel Yovana Quispe , Ferraciolli Clarissa Jesus , Simino Giovana de Paula Rezende , Goveia Vania Regina , Guimarães Gilberto de Lima
Published: June 2023

Objetivo: estimar a incidência, tempo de ocorrência de eventos adversos e tempo de permanência da hipodermóclise no idoso Método: Pesquisa realizada com 127 idosos em cuidados paliativos. A avaliação da hipodermóclise foi realizada a cada 24 horas até a ocorrência do evento. Realizou-se análise descritiva, calculando as proporções e a taxa de incidência por 100 punções/pacientes. Resultados: A taxa de incidência dos eventos adversos foi de 22,8% para a hipodermóclise e 27% para os indivíduos em uso de hipodermóclise. O cateter permaneceu em média quatro dias, sendo no mínimo um dia e no máximo 15 dias; a chance de eventos adversos no primeiro dia foi de 6%, de 28% no quinto dia e 48% no décimo. Conclusão: Incidência de eventos adversos foi pequena e localizada; tempo médio da permanência do cateter no local de inserção foi de quatro dias e as probabilidades de apresentar complicações aumentaram no decorrer dos dias.
Le Centre Technique Forestier Tropical est à votre service
Authors: Marcon Y.
Published: June 2023

Le Centre Technique Forestier Tropical (ex-Section Technique Forestière) opère depuis le 1er janvier 1950 en tant que société commerciale privée et peut effectuer des recherches sur commande. Ses différents départements (Documents, Equipement, Technologie, Anatomie, Chimie, Conservation) disposeront d'ici la fin de l'année de locaux et d'équipements modernes. Le Centre souhaite travailler en étroite collaboration avec les forestiers professionnels qui utilisent ses recherches. Il peut fournir des spécialistes pour des travaux à l'étranger si nécessaire.
Protection des bois en grumes au Cameroun
Authors: Alliot H. , Ivanès P.
Published: June 2023

Les auteurs rappellent les excellents résultats obtenus avec des produits chimiques contre les attaques d'insectes sur les rondins de Limbo, au Moyen Congo.
Pour utiliser ces produits de façon courante, il était nécessaire de les adapter à d'autres espèces sous divers climats tropicaux. Un ingénieur de la Société Progil vient de mettre au point cette technique au Cameroun. Les ennemis biologiques du bois : insectes et champignons, sont très rapides dans leurs attaques et ont souvent un agent physique supplémentaire : la fissure. Le traitement consiste en une application par pulvérisation très peu de temps après l'abattage.
Le produit efficace : Cryptogil EA6, possède à la fois des propriétés insecticides et fongicides. Il s'utilise en émulsion avec de l'eau (dose : produit 1/3 ; eau 2/3). Certaines essences de bois doivent être écorcées avant l'application du traitement, d'autres non. Dans la plupart des cas, les écorces lisses adhérentes seront laissées en place, et les écorces rugueuses légèrement adhérentes seront soulevées. Par exemple, le Frake Limbo (Terminalia Superba Engl. et Diels) devra être écorcé et l'Ilomba (Pycnanthus Kombo Warb) ne devra pas l'être.
Dans certains cas, il est nécessaire d'effectuer un traitement supplémentaire, en particulier au port d'embarquement. Des indications sont également données concernant l'appareil de pulvérisation qui doit être solide mais léger et ne pas comporter de parties en caoutchouc naturel. Il est préférable qu'ils soient en matière plastique ou en aluminium plutôt qu'en cuivre ou en laiton.
Humidité des bois en grumes et prix de transport
Authors: Sallenave P.
Published: June 2023

En France, la consommation de bois tropicaux est encore très faible et ne représente que 2,5 % de la consommation totale de bois qui s'élève à environ 10 000 000 mètres cubes par an.
Les bois tropicaux sont pourtant bien connus et appréciés, mais ils sont malheureusement trop chers. Actuellement, 90 % du bois importé est constitué de grumes carrées ou rondes, dont le taux d'humidité varie entre 50 et 90 %, avec une moyenne de 65 %.
Compte tenu de la production en sciages et planches dans lesquels l'aubier et le cœur tendre ont été éliminés (environ 50 %), un simple calcul arithmétique montre que le transport des grumes est illogique : on n'embarque en effet que 36,4 % des bois commerciaux coupés à l'équerre et apportant 10 à 20 % d'humidité et 63,6 % de déchets (eau à évaporer et déchets de bois, sciure, etc...).
De gros efforts sont donc à entreprendre afin d'améliorer et de développer le sciage dans les territoires d'outre-mer.
Le transport des grumes sur véhicules à roues
Authors: Martin P.H.
Published: June 2023

Le transport de grumes par route s'effectue de préférence par un attelage composé d'un camion couplé à une semi-remorque spécialisée. Toutefois, ce type d'attelage doit être étudié en fonction de l'objectif à atteindre.
Il doit être facile à manœuvrer en marche arrière et en marche avant ; la remorque doit être attelée au camion au moyen d'une perche extensible permettant une adaptation rapide à la longueur des grumes ; elle doit également être équipée de freins et construite de manière à pouvoir être hissée sur le camion lorsqu'elle est vide.
La meilleure solution est le train de grumes moderne qui est équipé pour un auto-chargement rapide au moyen d'un treuil à deux tambours et à deux vitesses fonctionnant à l'aide de la puissance du moteur. Il devrait également être conçu pour le déchargement mécanique.
Prospections en chambre
Authors: Aubréville A.
Published: June 2023

De nos jours, de nombreux scientifiques et techniciens visitent les forêts tropicales à travers le monde mais elles restent encore mal connues. La masse des travaux publiés est cependant considérable et M. Aubréville a jugé utile de suivre ces travaux dans une sorte d'étude critique. Il se propose donc, au cours de ses recherches, de faire des relevés analytiques accompagnés des commentaires que lui suggèrent son expérience et sa connaissance du milieu tropical.
Polissemia, variança, versão
Authors:   Universidade Estadual de Campinas, Dias Cristiane Pereira Costa , Costa Greciely Cristina da ,   Universidade Estadual de Campinas, Barbai Marcos Aurelio ,   Universidade Estadual de Campinas
Published: June 2023

O volume 13 da série Escritos, "Polissemia, Variança, Versão", explora o papel transformador da linguagem e como ela produz múltiplos sentidos. Os trabalhos apresentados propõem uma análise mais complexa das noções de polissemia, variança e versão, destacando sua relação com o sujeito na história. O livro é resultado de uma disciplina ministrada no Programa de Pós-Graduação em Divulgação Científica e Cultural da Unicamp, que se desenrolou como um laboratório experimental das palavras, formulações, textualizações dos sentidos, explorando o múltiplo, a variança, a versão.
PENGARUH VARIABEL EKONOMI MAKRO(INFLASI, KURS RUPIAHDAN FLUKTUASI HARGA EMAS DUNIA)TERHADAP RETURN SAHAM SYARIAH
Authors: Prasetyo Yoyok , Athoillah Mohamad Anton , Rosadi Aden
Published: June 2023

Penelitian ini dilatarbelakangi oleh adanya beberapa yangberpengaruh terhadap return saham Syariah di Indonesia. Penelitian bertujuan mengidentifikasi pengaruh variabel ekonomi makro pada level nasional maupun internasional. Variabel makro ekonomi level national berupa: inflasi, kurs Rupiah terhadap Dollar Amerika, adapun variabel makro level internasional berupa fluktuasi harga emas dunia terhadap return saham Syariah di Indonesia yang direpresentasikan dengan Jakarta Islamic Index ( JII). Metode penelitian yang digunakan kuantitatif dengan analisis regresi linear berganda, dengan periode penelitian dimulai Januari 2016 sampai dengan Desember 2017. Dari hasil penelitian didapatkan bahwa ketiga variabel makro ekonomi diatas secara simultan berpengaruh signifikan terhadap return JII. Adapun secara parsial, variabel inflasi berpengaruh tidak signifikan terhadap return JII dengan hubungan arah negatif. Variabel kurs rupiah berpengaruhtidak signifikan terhadap return JII. Sedangkan variabel fluktuasi harga emas dunia berpengaruh signifikan terhadap JII dengan arah hubungan positif. Ketiga variabel ekonomi makro sebagai variabel bebas diatas berkontribusi sebesar 25,4% terhadap perubahan variabel terikat yang berupa return JII. Berarti masih banyak variabel lain, baik makro maupun mikro yang dapat menerangkan return JII. Kesimpulan yang diperoleh dari penelitian ini adalah bahwa ketiga variabel ekonomi makro secara simultan berpengaruh signifikan terhadap return JII. Namun secara partial ada yang berpengaruh dengan hubungan positif maupun negatif dan ada juga yang tidak berpengaruh.
Morfometria e evolução de feições erosivas de grandes dimensões no Noroeste do Paraná
Authors: Oliveira Marianne , Santos Leonardo José Cordeiro , Oliveira José Guilherme de
Published: June 2023

A região noroeste do estado do Paraná apresenta feições erosivas de grande dimensão, relacionadas principalmente ao uso e ocupação atual do solo, entretanto, existem outras feições, com características distintas das atuais, associadas as condições climáticas presentes no Quaternário. Utilizando índices morfométricos (elevação, declividade, amplitude altimétrica e Chi) e evidências de campo buscou-se desenvolver um modelo de evolução espacial dessas feições erosivas localizadas sobre um divisor hidrográfico, situado entre as bacias do Ivaí e Paranapanema. Para isto foi necessário extrair a morfometria das feições, avaliar a estabilidade dos divisores por algoritmos aplicados a modelos digitais de elevação e caracterizar a rede de drenagem. Para responder aos objetivos utilizou-se os seguintes métodos e técnicas: aquisição de imagens de campo com RPA; caracterização da rede de drenagem por algoritmos matemáticos e desenvolvimento de um modelo evolutivo. Foram definidos quatro estágios de evolução para as feições; partindo da configuração atual da paisagem, passando pelos processos de ajuste fluvial a partir de capturas chegando ao estágio final, que seria a coalescência de todas as feições e formação de um agrupamento maior distinto do relevo da região.
Morphotectonic and morphostructural investigation in northwestern Minas Gerais State, Brazil: a lineament mapping assessment
Authors: Bragança Mário Teixeira Rodrigues , Barros Luiz Fernando de Paula , Oliveira Déborah de
Published: June 2023

This study aimed to investigate whether linear natural features are associated with structural or tectonic control of landforms and current drainage patterns in northwestern Minas Gerais State (Southeastern Brazil). To answer this question, more than 1,700 lineaments were manually mapped in a broader area encompassing the Paracatu and Urucuia River catchments. One satellite image scene (Operational Land Imager/Landsat-8), three different digital elevation models (Shuttle Radar Topography Mission, Advanced Spaceborne Thermal Emission and Reflection Radiometer-Global digital elevation model, and Advanced Land Observing Satellite-Phased Array L-band Synthetic Aperture Radar), and digitised analogical maps (geologic and topographic maps) were used to draw linear geometric features representing the lineament population. The resulting vector databases were integrated in a Geographic Information System for quantitative and spatial analyses, which resulted in two main trending lineament sets: NNW-SSE and NE-SW. Subsequent field assessments revealed that numerous lineaments from the first set were correlated to the formerly Upper Precambrian reverse and strike-slip faults. The second set were correlated to NE-SW normal faults derived from the Mesozoic-Cenozoic tectonic event following the breakup of Gondwana. These datasets contribute to a better understanding of the regional-, sub-regional-, and catchment-scale features underlying the structural control of the drainage network arrangement and pattern, which present long straight channels and are interrupted by anomalous and prominent bends that strictly fit major structural directions.
Preservice Teacher Study Abroad Language Immersion and Implicit and Explicit Beliefs About Dual Language Learners
Authors: Tripp Lucretia Octavia , Harrison Jamie , Love Angela
Published: June 2023

This study uses an Implicit Association Test and a self-report instrument of explicit beliefs to explore implicit and explicit beliefs and attitudes of pre-service teachers about DLLs. Study participants from one United States University in the Southeast were comprised of participants and non-participants of a study abroad language immersion experience. Overall, pre-service teachers in this study (n = 53) held balanced implicit attitudes about DLLs and positive explicit attitudes. Non-study abroad participants held negative explicit views of second language acquisition and lacked understanding of appropriate pedagogical choices for DLLs as compared to their study abroad participant counterparts.
Privacy-Preserving and Secure Solutions for Online English Education Platforms
Authors: Yin Jiming , Cui Jie
Published: June 2023

With the daily increasing demands for higher-quality services, mobile Internet of Things (MIoT) are facing various challenges, such as communication security, availability, scalability, etc. Its changing topology features bring a lot of trouble when solving the above problems. Though the evolved cellular network is expected to bring promising solutions, some inherent problems in traditional MIoTs may keep hindering its development. Thus, to overcome above problems, we propose a software-defined MIoTs-based model providing communication security and privacy protection under emergencies. In our scheme, the control plane is responsible to compute routes for online learning devices (OLDs), and forward entries for switches. Taking use of information that OLDs and facilities collect, controller is able to coordinate the overall situation. To ensure the authenticity and reliability of messages sent by OLDs, signature and authentication should be provided. We also introduce an emergency-dealing system. It transplants the multicast technology into software-defined MIoTs to generate a Steiner Tree among impacted nodes, so that OLDs will be informed as soon as emergency happening. The security analysis proves that our scheme is able to ensure the communication security in software-defined MIoTs. The evaluation of performance indicates that our scheme outperforms other existing schemes.
Leadership towards Sustainability: A Review of Sustainable, Sustainability and Environmental Leadership
Authors: Boeske Jane
Published: June 2023

Leadership and sustainability have been researched and examined concurrently. We know much about sustainable, sustainability and environmental leadership as separate areas of research and the leadership behaviours and practices that facilitate achievement of sustainability outcomes. Whilst these research streams have developed alongside each other, we know little about the similarities and differences of each of these three leadership approaches. The purpose of this paper is to review and compare which sustainable, sustainability and environmental leadership approaches are predictive of improved organizational performance with a view to understanding leadership towards sustainability. Through a comprehensive review of the extant literature, we integrate the three leadership approaches and highlight areas of similarity and difference. From a theoretical perspective, this paper seeks to make a significant contribution to the scholarly literature by building on current knowledge and developing a unified framework that combines our findings on leadership practices and behaviours in terms of the types of leadership required for achieving sustainability outcomes. By unifying existing frameworks and clarifying points of integration and differentiation under the umbrella of ‘leadership towards sustainability’, this paper seeks to advance research on leadership approaches. From a practical perspective, a cohesive set of leadership behaviours and practices will be emphasized so that leaders can adapt these to suit the context of their organization, thus helping leaders make sense of the literature to inform their practice and reach sustainability goals. Thus, the main goal of this paper is to identify a range of leadership behaviours and practices that are required to improve the performance of sustainability in organizations thus informing the broader leadership field.
Dynamic Output Feedback and Neural Network Control of a Non-Holonomic Mobile Robot
Authors: Cardona Manuel , Serrano Fernando E.
Published: June 2023

In this paper is presented the design and syntheis of a dynamic output feedback neural network controller for a non-holonomic mobile robot. First the dynamic model of a non-holonomic mobile robot is presented, in which these constraints are considered for the mathematical derivation of a feasable representation for this kind of robot. Then two control strategies are provided based on kinematic control for this kind of robot. The first control strategy is based on driftless control, this means, that considering that the velocity vector of the mobile robot is orthogonal to its restriction a dynamic output feedback and neural network controller is designed in order that the control action would be zero only when the velocity of the mobile robot is zero. The Lyapunov stability theorem is implemented in order to find a suitable control law. Then another control strategy is designed for trajectory tracking purposes, which similar to the driftless controller, a kinematic control scheme is provided but suitable to implement in more sophisticated hardware. In both control strategy a dynamic control law is provided along with a feedforward neural network controller, so in this way, by the Lyapunov theory the stability and convergence to the origin of the mobile robot position coordinates is ensured. Finally, two numerical experiment are presented in order to validate the theoretical results synthetized in this research study. Discussions and conclusions are provided in order to analyze the results found in this research study.
Accuracy Improved Classification and Regression Tree (CART) Model: Diabetes Prediction Using Minority Over-Sampling and Particle Swarm Optimization Techniques
Authors: Sukestiyarno Yohanes Leonardus , Rofif Mahrus Zufar
Published: June 2023

Diabetes is a serious health problem throughout the world, including in Indonesia. The International Diabetes Federation (IDF) reports that the number of adults with diabetes is increasing every year. The Behavioral Risk Factor Surveillance System (BRFSS) is a survey conducted by the Centers for Disease Control and Prevention (CDC) in the United States. Classification methods in data mining techniques are used to classify diabetics and non-diabetics. The data mining process is carried out by preprocessing, feature selection, and dataset classification stages. In the preprocessing stage, data cleaning, data formatting, and data oversampling are carried out using the Synthetic Minority Over-sampling Technique (SMOTE). Next, the feature selection stage is carried out using the Particle Swarm Optimization (PSO) algorithm to find the best attributes. The dataset classification stage is carried out using the CART Model Decision Tree algorithm. The results of the performance evaluation of the CART algorithm are calculated using the confusion matrix and the MAE value, the results obtained for the CART algorithm without SMOTE and PSO obtained the best accuracy of 75.34% and the MAE value of 0.2466, while the CART algorithm using SMOTE and PSO can increase accuracy by 10 .94% to 86.28% and an MAE value of 0.1372.
Antibacterial Thermo-Sensitive Silver Hydrogel Nanocomposite Improves Wound Healing
Authors: Amiri Nafise , Ghaffari Sahand , Hassanpour Ida , Chae Taesik , Jalili Reza , Kilani Ruhangiz , Ko Frank , Ghahary Aziz , Lange Dirk
Published: June 2023

Introduction: Among the many factors that may limit effective wound healing in patients with chronic ulcers, bacterial infection and poor cell recruitment are primary causes that contribute to prolonged healing. Thus, a novel strategy that aims to prevent bacterial infection within the wound, while at the same time providing structural scaffolding that promotes endogenous tissue repair, would be of great interest. Here, we developed a thermo-sensitive silver nanoparticle hydrogel composite as an antibacterial nutritional scaffold for the wound that contains all nutrients required for cell growth while preventing bacterial infection with the ability to fill up all the cavities and void areas in wounds regardless of their geometry.
Methods: Silver nanoparticles (AgNPs) were synthesized by chemical reduction. After characterization, silver hydrogel nanocomposite was developed by reconstitution of collagen-based hydrogel powder in a nanoparticle suspension of varying AgNPs concentrations (200, 400, and 600 ppm). The antibacterial activity of the formulations was examined in vitro and in vivo in subcutaneous implant infected model. The wound healing efficacy of the hydrogel nanocomposite was also evaluated using a splinted wound model in rats through comparison of clinical wound measurements and histological assessments. Cytocompatibility assay and biochemical analysis of blood at the end of in vivo wound healing study were performed to evaluate the safety of formulations.
Results: The synthesized nanoparticles were spherical and stable. While hydrogel alone did not show any bacterial reduction in vitro, the inhibition of bacterial growth was significant in all silver hydrogel nanocomposites compared to controls (p <0.05) and was dose-dependent, with maximum reduction observed in the 600 ppm group (4.56±0.26 LOG CFU/mL, P<0.001). All concentrations of AgNPs hydrogel composites showed significant antibacterial activity in vivo as well (P<0.0001). Treatment of splinted wounds with AgNPs hydrogel composite resulted in faster wound closure and accelerated wound re-epithelialization. The formulations were non-cytotoxic and did not differ significantly in hematological and biochemical factors from the control group in in vivo study.
Conclusions: By presenting promising antibacterial and wound healing activity, silver hydrogel nanocomposite offers a safe therapeutic option that can be used as a functional scaffold for an acceleration of wound healing.
Aerobic Exercise Training Improves Calcium Handling and Cardiac Function in Rats with Heart Failure Resulting from Aortic Stenosis
Authors: Da Silva Vitor Loureiro , Mota Gustavo Augusto Ferreira , De Souza Sérgio Luiz Borges , De Campos Dijon Henrique Salomé , Melo Alexandre Barroso , Vileigas Danielle Fernandes , Coelho Priscila Murucci , Sant’Ana Paula Grippa , Padovani Carlos , Lima-Leopoldo Ana Paula , Bazan Silméia Garcia Zanati , Leopoldo Andre Soares , Cicogna Antonio Carlos
Published: June 2023

Aerobic exercise training (AET) has been used in the management of heart disease. AET may, totally or partially, restore the activity and/or expression of proteins that regulate calcium (Ca2+) handling, optimize intracellular Ca2+ flow, and attenuate cardiac functional impairment in failing hearts. However, the literature presents conflicting data regarding the effects of AET on Ca2+ transit and cardiac function in rats with heart failure resulting from aortic stenosis. The objective of this study was to evaluate the effects of AET on calcium handling and cardiac function in rats with heart failure due to aortic stenosis. Wistar rats were distributed into two groups: control (Sham; n= 61) and aortic stenosis (AoS; n= 44). After 18 weeks, the groups were redistributed into: non-exposed to exercise training (Sham, n = 28 and AoS, n = 22) and trained (Sham-ET, n = 33 and AoS-ET, n = 22) for 10 weeks. Treadmill exercise training was performed with a velocity equivalent to the lactate threshold. Echocardiogram, isolated papillary muscle, and isolated cardiomyocyte analyzed cardiac function. During isolated papillary muscle assay and isolated cardimyocyte was evaluated Ca2+. The expression of regulatory proteins of diastolic Ca2+ was analyzed via Western Blot. AET attenuated the diastolic dysfunction and benefited the systolic function. AoS-ET animals presented better response to post-rest contraction, and SERCA2a and L-type Ca2+ channels blocked than the AoS. Furthermore, AET was able to improve aspects of the mechanical function and the responsiveness of the myofilaments to the Ca2+ of the AoS-ET animals. AoS animals presented alteration in the protein expression of the SERCA2a and NCX, and AET restored SERCA2a and NCX levels near normal values. Therefore, AET increased SERCA2a activity, improved the cellular Ca2+ influx mechanism, and increased myofilament responsiveness to Ca2+, attenuating cardiac dysfunction at cellular, tissue, and chamber levels in animals with aortic stenosis and heart failure.
Estimation of Salt Intake in Normotensive and Hypertensive Dominican Adults: Assessment of 24 H Sodium and Potassium Urinary Excretion
Authors: García-Lithgow Carlos Heriberto , Durán-Cabral Madeline , Winter-Matos Alexandra , García-Estrella Kilsaris , García-Durán Julen , Di-Sanzo Estefanía , Martínez-De-La-Cruz Nicole , Rodríguez-Abreu Julia , Olmedilla-Alonso Begoña
Published: June 2023

Higher salt (sodium) intake has been associated with a higher blood pressure (BP). The association degree may be influenced by factors such as age, origin and dietary components. This study aimed to evaluate the 24-hours urinary sodium (Na) and potassium (K) excretion in normotensive and hypertensive Dominicans adults and estimate their salt intake. 163 volunteers (18-45, 46-80 years) participated in a cross-sectional study. 24-hours Na and K urinary excretion were measured using an ion selective electrode technique. Na and K urinary excretion (99.4±46.5 and 35.0±17.5 mmol/24h) did not correlated with BP, except in the normotensive group in which K correlated with SBP (0.249, p=0.019). Na and K excretion were similar for normo- and hypertensive subjects. Na-to-K molar ratio (3.1±1.3) was higher in younger subjects (p=0.040). Na-to-K ratio was associated with DBP in the total group (r=0.153, p=0.052), in the hypertensive group (r=0.395, p<0.001) and in the older group with SBP (0.350, p=0.002) and DBP (0.373, p<0.001). In the older group, Na-to-K ratio and DBP correlated after controlling for subjects with hypertension controlled by treatment (r=0.236, p=0.041). The Na-to-K ratio correlated, when salt intake was over 5g/d (52.2%), with SBP (rho=0.219, p=0.044) and DBP (rho=0.259, p=0.017). Determinants of BP were age-dependent and in younger subjects were: sex (SBP, beta: 14.02±2.87, p<0.001) and body mass index (BMI) (beta:-12.07±3.72, p=0.001, beta:9.44±2.87, p=0.001, for SBP and DBP, respectively) and, in the olders, the Na-to-K ratio, for SBP (beta:6.7±2.4, p=0.005) and DBP (beta:3.8±1.1, p<0.001). The mean Na and salt intakes (2.3 and 5.8 g/d) were slightly higher and K intake lower (1.4 g/d) than WHO recommendations.
Multicomponent Reactions as an Efficient and Facile Alternative Route in Organic Synthesis and Applications
Authors: Mohlala Reagan Lehlogonolo , Rashamuse Thompho Jason , Coyanis Elena Mabel
Published: June 2023

Multicomponent reactions (MCRs) have been used for more than a century; since their discovery in 1850 by Strecker. To date, MCRs route is regarded as a beneficial strategy due to its capacity to quickly produce molecular diversity and structural complexity of interest for a variety of applications. Despite having famous MRCs such as the Ugi, Passerini, Biginelli, and Hantzsch, this re-view portrays the importance of MCRs in the synthesis of desired products towards applications such as medicinal purposes, sustainable chemistry, and polymerisation. MCRs provide ad-vantages such as reducing the number of sequential multiple reactions to one step, atom economy, recyclable catalysts, mild conditions, preventing waste and reduce solvent use.
HPV Vaccine Knowledge and Hesitancy among Health College Students at a Saudi University
Authors: Aldawood Esraa , Dabbagh Deemah , Alharabi Sarah , Alzamil Lama , Faqih Layla , Alshurafa Hassan H. , Dabbagh Rufaidah
Published: June 2023

Human papillomavirus (HPV) infection is a widespread sexually transmitted infection linked to various types of cancers. Although vaccination against HPV is available, global HPV vaccination rates remain low. This study aimed to evaluate the awareness and knowledge of the HPV vaccine and to identify predictors associated with vaccine hesitancy among health college students in Saudi Arabia. A cross-sectional survey was distributed to students enrolled in health colleges. The association of vaccine hesitancy with sociodemographic characteristics was examined using logistic regression analysis. The study found that approximately half of the students (49.9%) were aware of the HPV vaccine. Students from the College of Medicine showed the highest level of knowledge. Only a small proportion (5.2%) reported receiving the vaccine. The overall HPV vaccine hesitancy was 59.1% (43.9% for women and 75.9% for men). The most common reasons for vaccine hesitancy was not knowing enough about it. Men were twice as likely as women to believe that they did not need the HPV vaccine. The odds for HPV vaccine hesitancy were greater among men and younger age group compared to women and older age group. In conclusion, the study underscores the importance of awareness campaigns on HPV vaccination, targeting primarily male students.
Phosphorylation Mimetic of Myosin Regulatory Light Chain Mitigates Cardiomyopathy-induced Myofilament Impairment in Mouse Models of RCM and DCM
Authors: Kazmierczak Katarzyna , Liang Jingsheng , Maura Luis Guillermo , Scott Natissa Kelsey , Szczesna-Cordary Danuta
Published: June 2023

This study focuses on mimicking constitutive phosphorylation in the N-terminus of the myosin regulatory light chain (S15D-RLC) as a rescue strategy for the mutation-induced cardiac dysfunction in transgenic (Tg) models of restrictive (RCM) and dilated (DCM) cardiomyopathy caused by mutations in myosin essential (ELC) or regulatory (RLC) light chains. S15D-RLC phosphomimetic was reconstituted in left ventricular papillary muscle (LVPM) fibers from two mouse models of cardiomyopathy, RCM-E143K ELC and DCM-D94A RLC, along with their corresponding Tg-ELC and Tg-RLC wild type (WT) mice. The beneficial effects of S15D-RLC in rescuing cardiac function were manifested by S15D-RLC-induced destabilization of the super-relaxed (SRX) state that was observed in both models of cardiomyopathy. S15D-RLC promoted a shift from the SRX state to the disordered relaxed (DRX) state, increasing the number of heads readily available to interact with actin and produce force. Additionally, S15D-RLC reconstituted fibers demonstrated significantly higher maximal isometric force per cross-section of muscle compared with reconstitution with WT-RLC protein. The effects of the phosphomimetic S15D-RLC were compared to those observed for Omecamtiv Mecarbil (OM), a myosin activator shown to bind to the catalytic site of cardiac myosin and increase myocardial contractility. A similar SRX↔DRX equilibrium shift was observed in OM=treated fibers as in S15D-RLC-reconstituted preparations. Additionally, treatment with OM resulted in significantly higher maximal pCa 4 force per cross-section of muscle fibers in both cardiomyopathy models. Our results suggest that both treatments with S15D-RLC and OM may improve the function of myosin motors and cardiac muscle contraction in RCM-ELC and DCM-RLC mice.
PEMANFAATAN FLY ASH SEBAGAI BAHAN SUBSTITUSI PARSIAL SEMEN PADA KOLOM STRUKTUR MODULAR BETON RAMAH LINGKUNGAN
Authors: Fashadad Ijlal , Habsya Chundakus , Agustin Rima Sri
Published: June 2023

Abstrak : Penelitian ini bertujuan untuk menganalisis penggunaan fly ash dengan variasi 10%, 15% dan 20% sebagai bahan substitusi parsial semen untuk menghasilkan nilai berat isi minimal, kriteria beton ramah lingkungan dan perbandingan biaya antara kolom struktur konvensional dan kolom struktur prapabrikasi. Metode penelitian yang digunakan yaitu metode eksperimen, dengan standar pengujian berat isi mengacu pada SK SNI T: 15-1991- 03. Mix design segmen kolom menggunakan perbandingan 1 Pc: 2,67 Ps: 2,9 Kr, FAS sebesar 0,55 dan diuji pada umur 28 hari. Sampel uji berat isi berdimensi 30 cm x 30 cm x 15 cm. Persentase optimal penggunaan fly ash yaitu 15% menghasilkan nilai berat isi optimal sebesar 2459,416 kg/m3. Pemanfaatan fly ash sebagai bahan substitusi parsial semen pada kolom memenuhi kriteria ramah lingkungan yaitu mengurangi gas emisi CO2 sebesar 40,74 kg per m3 campuran beton dengan variasi 15% fly ash dan mengurangi sampah bekisting sebesar 3,6 m2 setiap pembuatan 2–3 batang kolom struktur. Penggunaan metode prapabrikasi dapat mereduksi biaya pembuatan sebesar 15,58% dan waktu pembuatan sebesar 21,6%.  

Abstract :  This study aims to analyze the use of fly ash with variations of 10%, 15% and 20% as a partial substitution of cement to produce an optimal density value, environmentally friendly concrete criteria and the cost comparison between conventional structural columns and prefabricated structural columns. The research method used was the experimental method, with standard density testing referring to SK SNI T: 15-1991-03. Mix design column segment used a ratio of 1 Pc: 2.67 Ps: 2.9 Kr, FAS of 0.55 and tested at 28 days of age. The density test sample has dimensions of 30 cm x 30 cm x 15 cm. The optimal percentage of use of fly ash is 15% resulting in an optimal density value of 2459.416 kg/m3. The utilization of fly ash as a cement column partial substitusi meet environmental criteria, namely reducing CO2 emissions of 40.74 kg per m3 of concrete mix wish variation in the use of 15% fly ash and reduce waste formwork of 3.6 m2 every manufacture 2- 3 column structure rods. The use of prefabricated methods can reduce manufacturing costs by 15.58% and manufacturing time by 21.6%. 
Analisis Kinerja Seismik Struktur 10 Lantai Beton Bertulang dengan Metode Pushover Analysis
Authors: Putri Andina , Herdinata Shandria , Khala Christianto Credidi Septino , Sari Oryza Lhara
Published: June 2023

Abstrak:Indonesia yang berada pada jalur gempa Pasifik dan jalur gempa Asia memiliki resiko gempa yang tinggi. Pada tahun 2018 terjadi gempa dengan kekuatan besar yang berpusat di Palu dan getarannya terasa hingga ke Kalimantan Timur. Hal ini tentunya menunjukkan pentingnya evaluasi struktur gedung bertingkat terhadap gempa di wilayah Balikpapan. Tujuan dari penelitian ini adalah untuk mengetahui kinerja pada struktur Hotel Platinum di Balikpapan agar dapat diketahui kinerja struktur jika mengalami beban gempa yang melebihi beban gempa yang direncanakan. Analisis pushover mengacu pada SNI 1726:2019 dan ATC-40. Beban yang digunakan mengacu pada SNI 1727:2013, PPIUG 1983 dan PPPURG 1987. Pada penelitian ini dilakukan pemodelan dan analisis struktur metode pushover dengan program bantu. Analisis dilakukan pada gempa Balikpapan sebagai lokasi eksisting. Hasil analisa pushover menghasilkan nilai gaya geser sebesar 12164,73 KN, displacement atap 6 cm, periode efektif 1,851 dan redaman efektif 5% untuk pushover pada gempa Balikpapan. Berdasarkan pengendalian SNI 1726: 2019, struktur memenuhi persyaratan geser dan simpangan maksimum sehingga struktur aman. Kriteria kinerja struktur berdasarkan ATC-40 adalah segera ditempati yaitu struktur tidak mengalami keruntuhan struktural atau non struktural dan bangunan dapat digunakan kembali.

Abstract:Indonesia, which is in the Pacific earthquake path and the Asian earthquake path, has a high earthquake risk even in Kalimantan, the island with the lowest earthquake risk level. The purpose of this study is to determind the performance of the Platinum Hotel structure located in Balikpapan, east Kalimantan, in order to know the performance of the structure if it is subjected to earthquake loads that exceed the planned earthquake load. Pushover analysis refers to SNI 1726: 2019 and ATC-40. The load used is referring to SNI 1727: 2013, PPIUG 1983 and PPPURG 1987. In this study, modeling and structure analysis of pushover methods with assistive programs was carried out. Analysis was carried out on the Balikpapan earthquake as the existing location. The results of the pushover analysis produced a shear force value of 12164.73 KN, a roof displacement of 6 cm, an effective period of 1.851 and an effective attenuation of 5% for a pushover in the Balikpapan earthquake. Based on the control of SNI 1726: 2019, the structure meets the maximum shear and deviation requirements so that the structure is safe. Structure performance criteria based on ATC-40 are immediate occupancy ie the structure does not experience structural or non-structural collapse and the building can be reused.
Pengalaman Mengajar dalam Jaringan Guru Desain Permodelan dan Informasi Bangunan pada Masa Pandemi Covid-19
Authors: Qori’ah Fasihatul , Sumarni Sri , Isnantyo Fajar Danur
Published: June 2023

Abstrak:Pandemi Covid-19 merupakan epidemi global yang mengganggu dan mempengaruhi berbagai aspek kehidupan. Setelah Coronavirus Disease (Covid-19) mewabah di Indonesia, sistem pendidikan tidak lagi dilakukan secara konvensional, tetapi dengan menggunakan sistem pembelajaran daring. Pembelajaran daring di salah satu SMK Negeri di Surakarta memberikan pengalaman mengajar baru bagi guru. Penelitian ini bertujuan untuk mengungkap pengalaman mengajar daring guru SMK selama pandemi Covid-19 berdasarkan perspektif teori agensi guru. Metode penelitian ini menggunakan pendekatan naratif dalam penelitian kualitatif. Partisipan terdiri dari tiga orang guru di salah satu SMK Negeri di Surakarta. Dalam penelitian ini digunakan analisis konten (analisis isi), dengan bantuan aplikasi NVIVO. Hasil penelitian ini diharapkan memberikan wawasan baru mengenai pengalaman mengajar daring guru SMK selama wabah pandemi Covid-19 yang nanti bisa dijadikan pijakan penentuan kebijakan untuk peningkatan pembelajaran daring di masa pandemi.

Abstract:The Covid-19 pandemic is a global epidemic that is disturbing and affecting various aspects of life. Following the corona virus disease (Covid-19) outbreak in Indonesia, the educational system was not further conventional but rather, it was by using online learning systems. Online study in one of the country's vocations in surakarta provides new teaching experience for teachers. The study was intended to uncover the near-death experience of teacher Vocational High School online during the Covid-19th pandemic based on the perspective of the teacher agency's theory. This research method employs a narrative approach in qualitative research. The participants consisted of three teachers in one of the country's texts in Surakarta. In this study used content analysis (content analysis), with the help of the NVivo application. This study is expected to provide new insights into the online teaching experience of teacher SMK during the Covid-19 pandemic that could be a hotbed for policy reinforcing greater online learning during the pandemic.