bluuebunny/crossref_metadata_2025 huggingface dataset:
New records of Gigantolaelaps wolffsohni (Mesostigmata: Laelapidae) in Chile, an ectoparasite of Oligoryzomys longicaudatus (Rodentia: Cricetidae): ecological aspects and relation to body size and sex of their host
Authors: Fuenzalida-Araya Karen , González-Aguayo Felipe , Moreno Lucila , Landaeta-Aqueveque Carlos , Santodomingo Adriana , Silva-de la Fuente Carolina , González-Acuña Daniel
Published: September 2022

The Gigantolaelaps mites (Mesostigmata: Laelapidae) are easily recognized by their large size. In Chile, Gigantolaelaps wolffsohni is the only recognized species Gigantolaelaps and it has only been reported from four localities, always in association with Oligoryzomys longicaudatus. Our research study aimed to contribute to the severely limited information about the ecology and distribution of G. wolffsohni in Chile and determine whether factors such as season, ecological region and weight-and sex of the host influence the abundance of this mite. We captured and assessed 329 O. longicaudatus in different seasons and localities. We classified sampled localities as being part of the Mediterranean, Template Forest, or Magellanic Forest ecoregion due to reported genetic and morphological differences of O. longicaudatus between ecoregions. Information about the season, ecoregion, and weight and sex of the host were recorded during mite sampling. These variables were assessed to determine their influence on mite abundance and prevalence through negative binomial and logistic regression models. We found 19 new localities where G. wolffsohni is distributed in Chile. These mites displayed an aggregated distribution in all ecoregions. We found that biogeography, weight, and sex of the host are not related to the abundance and prevalence of G. wolffsohni. Nonetheless, we found a strong association between the season and the abundance and prevalence of mites. All mites found were females; additionally, we found larva stage inside some female mites. We discussed the relationship between different ecological aspects and the abundance and prevalence of ectoparasites. Also, we discussed the finding of the larvae of G. wolffsohni, which means that this specie is at least larviparous, and finally, we discuss the specificity of Laelapidae mites.
Determinants of Banks Profitability: An Evidence from GCC Countries
Authors: Khan Shoaib
Published: September 2022

The research objective of the study is to investigate the determinants of profitability of banks’ operating in GCC (Gulf Cooperation Council) countries. The existing studies highlight the banks’ internal attributes and external factors that significantly influence profitability. The unbalanced panel data of 59 banks from the Bank scope database operating in six countries of GCC is used. Profitability is measured as return on assets (ROA) and return on equity (ROE) that have been used as dependent variables. Pooled OLS, fixed and random effects estimations are employed to explore the effect of explanatory variables internal factors, i.e. bank size, capital adequacy, asset quality, deposits ratio, asset management, operating efficiency and financial risk, and external factors, namely macroeconomic variables, GDP growth rate and inflation rate on dependent variables. Bank size and GDP growth have a significant and positive association with ROA. While Bank size and asset management have significant and positive impact, capital adequacy, financial risk, operating efficiency, and asset quality have a negative and significant impact on ROE. Fixed effects results are used for interpretation based on the Hausman test.
Delta variant: Partially sensitive to vaccination, but still worth global attention
Authors: Zhang Meng , He Yanchao , Jie Zhijun
Published: September 2022

The pandemic coronavirus disease 2019 (COVID-19) has rapidly spread to all countries worldwide. The emergence of its variants has exacerbated this problem. To date, many variants have been identified across the viral genome; the variants of concern are the focus of attention due to their higher transmissibility and resistance to vaccines, especially the delta variant. The delta variant has become the dominant severe acute respiratory syndrome novel coronavirus (SARS-CoV-2) variant worldwide, causing severe panic as it is highly infectious. A better understanding of these variants may help in the development of possible treatments and save more lives. In this study, we summarize the characteristics of the variants of concern. More importantly, we summarize the results of previous studies on the delta variant. The delta variant has a high transmissibility rate and increases the risk of hospitalization and death. However, it is partially sensitive to vaccines. In addition, nonpharmaceutical interventions are valuable during epidemics. These interventions can be used against the delta variant, but managing this variant should still be taken seriously.
Psychological Capital and Organizational Performance: The Mediating Role of Organizational Ambidexterity
Authors: Ghanizadeh Sohrab , Ardabili Farzad Sattari , Kheirandish Mohammad , Rasouli Eshagh , Hassanzadeh Mohammad
Published: September 2022

Background and purpose: Today’s dynamic environment is increasingly pressuring public organizations to be simultaneously flexible and efficient. The purpose of this study was to examine the mediating role of organizational ambidexterity in the relationship between psychological capital and the perfor-mance of public organizations that have bureaucratic limitations to their activity and are not as competitive as the private sector.

Methods: A questionnaire was developed and distributed among the employees of Management and Planning Organizations in 31 provinces in Iran, and a total of 373 questionnaires were returned. The data was analysed using CFA to validate the measures, and then the mediating effects of organi-zational ambidexterity was tested.

Results: The results indicated the significant relationship between psychological capital and organizational performance (B=0.55) and the positive mediation effect of organizational ambidexterity on this relationship (0.333).

Conclusion: The findings can help managers of public organizations to enhance their organizational performance by strengthening psychological capital and ambidexterity.
All-Russian scientific and practical conference dedicated to the 180th anniversary of the department and clinic of faculty surgery named after S.P. Fedorov
Authors: Romashchenko P. N. , Maistrenko N. A. , Kurygin Al. A. , Dovganiuk V. S.
Published: September 2022

Кафедра была основана 3 марта 1841 г. по предложению Николая Ивановича Пирогова. Он обращал внимание на то, что молодые врачи почти не имеют практической подготовки и оказываются беспомощными у постели больного. Для устранения этого пробела в образовании врачей Н. И. Пирогов предложил создать в академии, помимо двух существовавших хирургических кафедр, на которых проводились только теоретические занятия, еще одну с собственной клинической базой. Таким образом, впервые в истории Императорской медико-хирургической академии была организована клиническая кафедра во 2-м Сухопутном госпитале, получившая название госпитальной хирургической клиники, а ее первым руководителем стал Н.И. Пирогов.
Arterial thromboses: change of paradigm in the era of COVID-19 (review of literature)
Authors: Kazantsev A. N. , Devlikamova A. A. , Dmitrieva I. O. , Korotkikh A. V. , Artyukhov S. V. , Zarkua N. E. , Chernykh K. P. , Bagdavadze G. Sh.
Published: September 2022

This literature review focuses on the problem of peripheral arterial thrombosis in patients with COVID-19. Russian and international recommendations for the treatment of this cohort of patients were created in the period before the pandemic and do not take into account the new genesis of the development of the disease. In turn, this leads to the ineffectiveness of the existing methods of reperfusion, aimed primarily at removing the thrombus and administering anticoagulants/antiplatelet agents. The elimination of endotheliitis, as one of the key factors of arterial thrombosis, is not always possible, which is accompanied by the development of repeated thrombosis with further unfavorable events. The lack of prospective randomized trials, as well as information in the Interim Guidelines for the Prevention, Diagnosis and Treatment of New Coronavirus Infection (COVID-19) of the Ministry of Health of the Russian Federation, where infectious coronavirus hospitals operate, creates uncertainty in the choice of methods for treating arterial thrombosis when infected with SARS-CoV -2. This trend is associated with a high rate of amputations and deaths in patients with COVID-19. To date, there is no method of revascularization in the presence of arterial thrombosis that demonstrates optimal results for patients with new coronavirus infection.
About the first gastric surgeries performed in Saint Petersburg in the ХIХ century
Authors: Bagnenko S. F. , Yaitsky N. A. , Lazarev S. M.
Published: September 2022

The article is devoted to the history of gastric surgery in Saint Petersburg (Russia) in the XIX century. In the last decades of the 19th century, there was a breakthrough in surgery - surgeons from all over the world began to operate on the stomach. For the first time in Saint Petersburg and in Russia, Russian surgeons M.K. Kitaevsky, D.M. Monastyrsky and N.V. Ekk performed stomach resection for cancer by Billroth I method (M.K. Kitaevsky, 16.07.1881) and gastroenteroanastomosis for cicatrical pyloric stenosis (N.D. Monastyrsky, 13.03.1882), and at the meeting of the Society of Russian Doctors in Saint Petersburg in May 1882, V. Ekk proposed to overlap an anastomosis between the stump of the resected stomach and the loop of the small intestine that was realized by the Viennese surgeon T. Billroth only 3 years later in 1885, and got the name of the modification of gastric resection by the Billrot II method. It should be noted that M.K. Kitaevsky and N.D. Monastyrsky worked at Petropavlovsky Hospital - on the basis of which the Women's Medical Institute was established in 1897 (now the Pavlov First Saint Petersburg State Medical University).
Historical aspects of the development of the theory and practice of treating thermal injury in the soviet press of the 30s of the XX century
Authors: Sokolov V. A. , Mamaeva S. A. , Butrin Ya. L. , Samarev A. V.
Published: September 2022

The OBJECTIVE was to replenish and systematize the ideas about the achievements of Soviet scientists in the field of combustiology based on the analysis of the publication array on the problem of «Thermal injury» for the period 1920-1930s.

METHODS AND MATERIALS. A structural and substantive analysis of the array of publications on the problem of treating thermal injuries, revealed as a result of attracting a wide range of bibliographic resources, such as catalogs of leading libraries, current and retrospective indexes, and databases, has been carried out. The inclusion of new sources of information in the research space made it possible to discover and for the first time to introduce into scientific circulation a large number of scientific works that require a new understanding of the achievements of domestic doctors in the field of treating burns during this period, differently prioritizing, assessing the personalization of the contribution of scientists and research teams. The bibliographic indexes of Russian traumatology for 1924-1940, catalogs of the largest universal and branch (medical) libraries of St. Petersburg and Moscow have been investigated.

RESULTS. We found out that in the period from 1924-1940, 579 works on various aspects of thermal injury were published on the pages of the Soviet medical press, including materials from the speeches of researchers at scientific conferences and meetings of medical societies in various cities of our country.

CONCLUSION. The obtained results made it possible to restore and clarify many undeservedly forgotten facts of the history of Russian combustiology.
Original method for restoring the continuity of the lobar duct of the liver in case of iatrogenic damage
Authors: Avanesyan R. G. , Korolev M. P. , Pletnev M. Yu. , Sabri S. N. , Amirkhanyan T. V.
Published: September 2022

The OBJECTIVE was to demonstrate an original minimally invasive way to restore the continuity of the lobar duct after its complete intersection.

METHODS AND MATERIALS. The study included 3 patients aged 38, 56 and 69 years who underwent laparoscopic cholecystectomy for cholelithiasis, cholecystolithiasis in various medical institutions of the city. In all patients, the intersection of the right lobar duct with the formation of an external biliary fistula in the postoperative period was revealed. RESULTS. All patients underwent recanalization of the crossed duct on the first attempt. After the fistula was formed on the frame drainage, the flow of bile through the external biliary fistula gradually regressed: in one patient, bile leakage from the abdominal cavity stopped after two days, in two patients after a week. Drainages from the subhepatic space were removed in all patients on the 9th day after restoration of the continuity of the intersect duct. Kehr's drainage was removed after 12 days in one patient, after 21 days in another. Retrograde external drainage was removed from the third patient on the 5th day after restoration of the patency of the duct on the frame drainage. After control X-ray images, the external-internal frame drainages were blocked for patients on the 5-10th day after the operation. There were no leaks of contrast agent through the restored section of the duct.

CONCLUSION. The developed method of minimally invasive restoration of continuity and patency of the intersected and excised hepatic duct is an alternative to the traditional reconstructive biliodigestive bypass surgery. Long-term frame drainage of the bile duct in the area of damage allows forming sufficient diameter for an unobstructed passage of bile.
Academician Viktor Nikolaevich Shevkunenko (1872-1952) (on the 150th anniversary of the birth)
Authors: Romashchenko P. N. , Fomin N. F. , Maistrenko N. A. , Kurygin Al. A. , Semenov V. V.
Published: September 2022

The outstanding Russian scientist and teacher in the field of topographic anatomy and operative surgery, one of the initiators of the creation of the Academy of Medical Sciences of the USSR and its full member (1944), Honored Scientist of the RSFSR (1935), winner of the Stalin Prize of the first degree (1943), Lieutenant General of the Medical Service (1943), Professor (1912) Viktor Nikolayevich Shevkunenko was born on February 17 (29 new style), 1872 in the county town of Mezen, Arkhangelsk province. In 1895, he graduated from the Imperial Military Medical Academy. From 1912 to 1948, he headed the Department of Operative Surgery and Topographic Anatomy of the Academy. V.N. Shevkunenko is the founder of the doctrine of the type and age variability of human anatomy. As a result of many years of research carried out by the staff of the department, atypical forms of the structure and location of organs and anatomical structures were described in detail, optimal accesses and rational technique were justified when performing surgical interventions on different organs, depending on the typical, sexual and age topographic and anatomical features of patients. V.N. Shevkunenko is the founder of a major Russian school in the field of operative surgery and topographic anatomy: 44 of his students became professors. Academician V.N. Shevkunenko died on July 3, 1952 and was buried at the Theological Cemetery in Leningrad.
Spontaneous esophageal hematoma after kidney transplantation
Authors: Danieljan Sh. N. , Ibavov I. U. , Muslimov R. Sh. , Balkarov A. G. , Gasanov A. M.
Published: September 2022

Spontaneous esophageal hematoma is an extremely rare pathological condition, diagnosed mainly in patients with coagulopathy. We present the rarest case report of spontaneous esophageal hematoma, which occurred on the 5th day after allogeneic cadaveric kidney transplantation in a 53-year-old woman. Early diagnosis and treatment helped to achieve complete hematoma regression without complications.
Escape from Lubumbashi: A refugee’s journey on foot to reunite her family
Authors: Neethling Estelle
Published: September 2022

This is the true story of Adolphine, a refugee from the Democratic Republic of the Congo (DRC) who was twenty-two when she had to flee her home in the war-ravaged DRC in 1996. She walked thousands of kilometres across Southern Africa to be reunited with her husband Sepano in Cape Town after two years of a desperate search. Her incredible journey to escape the ruinous rule of Mobutu Sese Seko was filled with many moments of terror and despair, every country having its own share of xenophobia. She told the writer – the retired national tracing coordinator of the International Red Cross’s Restoring of Family Links programme in South Africa – “I felt as if the earth had teeth, I felt its bite when I was fleeing through Africa…”. The book contains twenty historic photos provided by Adolphine, of her family members.
Access to assistive technology for people with visual impairment
Authors: Shukla Kriti
Published: September 2022

Access to assistive technology (AT) is key to inclusion for people with disabilities in society and its development. Over 2.5 billion people need one or more of these devices globally, but about 1 billion do not have access. Access to these products is even more challenging for people with disabilities. This article reviews national data and government initiatives to understand the present situation of access to assistive technologies and the challenges faced by people with visual impairment in acquiring them. Further, the article discusses the key policy recommendations to enhance access to AT.
Initial neurocritical care of severe traumatic brain injury: New paradigms and old challenges
Authors: El-Swaify Seif Tarek , Kamel Menna , Ali Sara Hassan , Bahaa Bassem , Refaat Mazen Ahmed , Amir Abdelrahman , Abdelrazek Abdelrahman , Beshay Pavly Wagih , Basha Ahmed Kamel Mohamed Moner
Published: September 2022

Background:

Early neurocritical care aims to ameliorate secondary traumatic brain injury (TBI) and improve neural salvage. Increased engagement of neurosurgeons in neurocritical care is warranted as daily briefings between the intensivist and the neurosurgeon are considered a quality indicator for TBI care. Hence, neurosurgeons should be aware of the latest evidence in the neurocritical care of severe TBI (sTBI).

Methods:

We conducted a narrative literature review of bibliographic databases (PubMed and Scopus) to examine recent research of sTBI.

Results:

This review has several take-away messages. The concept of critical neuroworsening and its possible causes is discussed. Static thresholds of intracranial pressure (ICP) and cerebral perfusion pressure may not be optimal for all patients. The use of dynamic cerebrovascular reactivity indices such as the pressure reactivity index can facilitate individualized treatment decisions. The use of ICP monitoring to tailor treatment of intracranial hypertension (IHT) is not routinely feasible. Different guidelines have been formulated for different scenarios. Accordingly, we propose an integrated algorithm for ICP management in sTBI patients in different resource settings. Although hyperosmolar therapy and decompressive craniectomy are standard treatments for IHT, there is a lack high-quality evidence on how to use them. A discussion of the advantages and disadvantages of invasive ICP monitoring is included in the study. Addition of beta-blocker, anti-seizure, and anticoagulant medications to standardized management protocols (SMPs) should be considered with careful patient selection.

Conclusion:

Despite consolidated research efforts in the refinement of SMPs, there are still many unanswered questions and novel research opportunities for sTBI care.
Atomistic Origins of Biomass Recalcitrance in Organosolv Pretreatment
Authors: Sarkar Daipayan , Santiago Ian , Vermaas Josh
Published: September 2022

Secondary plant cell walls are made from three common biopolymers, cellulose, lignin, and hemicellulose, representing a critical feedstock for sustainable biomaterial production. Separating lignocellulosic biomass components for use in tailored sustainable energy and materials applications is challenging, as the biopolymers are in close proximity within the plant secondary cell wall. Organic solvents are used to pretreat recalcitrant biomass and separate the interacting polymers, solubilizing the lignin fraction for lignin-first valorization approaches. However, no single organosolv pretreatment approach has proven superior for heterogeneous biomass samples. Simulation offers a complementary atomic view into interactions between biomass components, resolving mechanistic hypotheses for how biomass composition influences separations processes. Using molecular dynamics simulations, we quantify lignin-cellulose interactions through binding free energies determined from 300 lignin polymer models in nine solvent environments, across four crystalline cellulose faces, with an aggregate simulation time of nearly 154 microseconds. The binding free energy determined from simulation categorizes the solvents. For poor lignin solvents, all lignin polymers bind strongly to cellulose. By contrast, polar protic solvents such as methanol and ethanol favor the unbinding between lignin and cellulose in all conditions, regardless of charge for the lignin monomer tested. Aprotic organic solvents separate lignin from cellulose only for uncharged lignin monomers, with charged lignin monomers associating to cellulose. While polar protic solvents are most effective at breaking apart lignin-cellulose interactions for charged lignin species, solvent dynamics highlight that there is no single optimal solvent to facilitate lignin-cellulose separation, particularly as some solvents demonstrate greater effectiveness for skewed S:G ratios. Instead, the optimal solvent for a given lignin sample will depend on the lignin compound and the net charge for the lignin polymers.
Engineering Solution-Processed Non-Crystalline Solid Electrolytes for Li Metal Batteries
Authors: Vadhva Pooja , Gill Thomas , Cruddos Josh , Said Samia , Siniscalchi Marco , Narayanan Sudarshan , Pasta Mauro , Miller Thomas , Rettie Alexander
Published: September 2022

Non-crystalline Li+-ion solid electrolytes (SEs), such as lithium phosphorous oxynitride, can uniquely enable high-rate solid-state battery operation over thousands of cycles in thin film form. However, they are typically produced by expensive and low throughput vacuum deposition, limiting their wide application and study. Here, we report a non- crystalline SE of composition Li-Al-P-O (LAPO) with an ionic conductivity >10-7 S cm-1 at room temperature by spin coating from aqueous solutions and subsequent annealing in air. Homogenous, dense, flat layers can be synthesised with sub- micron thickness at temperatures as low as 230 °C. Control of the composition is shown to significantly affect the ionic con- ductivity, with increased Li and decreased P content being optimal, while higher annealing temperatures result in decreased ionic conductivity. Activation energy analysis reveals a Li+-ion hopping barrier of 0.42(1) eV. Additionally, these SEs exhibit low room temperature electronic conductivity (<10-11 S cm-1) and moderate Young’s modulus of ≈54 GPa, which may be beneficial in preventing Li dendrite formation. In contact with Li metal, LAPO is found to form a stable, but high impedance passivation layer comprised of Al metal, Li-P and Li-O species. These findings should be of value when engineering non- crystalline SEs for Li-metal batteries with high energy and power densities.
Electrospun Polyacrylonitrile Silver Nanoparticle (PAN-AgNP) Nanocomposites as Alternative Antimicrobial Materials
Authors: Wang William , Pan Chieh-Yu , Huang Eng-Yen , Peng Bai-Jing , Hsu Jonathan , Clapper Jude
Published: September 2022

Infectious microbial diseases can easily be transferred from person to person in the air or via high contact surfaces. As a result, researchers must aspire to create materials that can be implemented in surface contact applications to disrupt pathogen growth and transmission. Silver (Ag) is known to possess antimicrobial activity and has been used in the past in various pharmaceutical applications. Herein, we examine the antimicrobial properties of polyacrylonitrile (PAN) nanofibers coated with different concentrations of silver nanoparticles (AgNPs). Polyacrylonitrile (PAN) was homogenized with varied weight concentrations of silver nitrate (AgNO3) in N,N-Dimethylformamide (DMF) solution, a common organic solvent that serves as both an electrospinning solvent and as a reducing agent that forms AgNPs. The subsequent colloids were electrospun into nanofibers, which were then characterized via various analysis techniques, including Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Energy Dispersive X-Ray (EDX) Analysis, Dynamic Light Scattering (DLS), and X-Ray Photoelectron Spectroscopy (XPS). 10 microbes, including 7 strains of Gram-positive bacteria, 2 strains of Gram-negative bacteria, and Candida albicans were incubated with cutouts of various PAN-AgNP nanocomposites using disk diffusion methods to test for the nanocomposites’ antimicrobial efficiency. We report that PAN-AgNP nanocomposites retain a certain degree of antimicrobial longetivity; samples stored for approximately 90 days demonstrate similar antimicrobial activity against Escherichia coli (E. coli) and Lactobacillus crispatus (L. crispatus) when compared to their newly electrospun counterparts. Moreover, our results indicate that PAN-AgNP nanocomposites successfully display antimicrobial activity against various bacteria and fungi strains regardless of their resistance to conventional antibiotics. Our study demonstrates that PAN-AgNP nanocomposites can potentially be applied to surfaces at risk of contracting microbial infections.
Protein Cargo Encapsulation by Virus-Like Particles: Strategies and Applications
Authors: McNeale Donna , Dashti Noor , Cheah Li Chen , Sainsbury Frank
Published: September 2022

Viruses and the recombinant protein cages assembled from their structural proteins, known as virus-like particles (VLPs), have gain wide interest as tools in biotechnology and nanotechnology. Detailed structural information and their amenability to genetic and chemical modification make them attractive systems for further engineering. This review describes the range of non-enveloped viruses that have been co-opted for heterologous protein cargo encapsulation and the strategies that have been developed to drive encapsulation. Spherical capsids of a range of sizes have been used as platforms for protein cargo encapsulation. Various approaches, based on native and non-native interactions between the cargo proteins and inner surface of VLP capsids, have been devised to drive encapsulation. Here we outline the evolution of these approaches, discussing their benefits and limitations. Like the viruses from which they are derived, VLPs are of interest in both biomedical and materials applications. The encapsulation of protein cargo inside VLPs leads to numerous uses in both fundamental and applied biocatalysis and biomedicine, some of which are discussed herein. The applied science of protein encapsulating VLPs is emerging as a research field with great potential. Developments in loading control, higher order assembly and capsid optimization are poised to realize this potential in the near future.
miR-329– and miR-495–mediated Prr7 down-regulation is required for homeostatic synaptic depression in rat hippocampal neurons
Authors: Inouye Michiko O , Colameo David , Ammann Irina , Winterer Jochen , Schratt Gerhard
Published: September 2022

Homeostatic synaptic depression (HSD) in excitatory neurons is a cell-autonomous mechanism which protects excitatory neurons from over-excitation as a consequence of chronic increases in network activity. In this process, excitatory synapses are weakened and eventually eliminated, as evidenced by a reduction in synaptic AMPA receptor expression and dendritic spine loss. Originally considered a global, cell-wide mechanism, local forms of regulation, such as the local control of mRNA translation in dendrites, are being increasingly recognized in HSD. Yet, identification of excitatory proteins whose local regulation is required for HSD is still limited. Here, we show that proline-rich protein 7/transmembrane adapter protein 3 (Prr7) down-regulation in dendrites of rat hippocampal neurons is necessary for HSD induced by chronic increase in network activity resulting from a blockade of inhibitory synaptic transmission by picrotoxin (PTX). We further identify two activity-regulated miRNAs, miR-329-3p and miR-495-3p, which inhibit Prr7 mRNA translation and are required for HSD. Moreover, we found that Prr7 knockdown reduces expression of the synaptic scaffolding protein SPAR, which is rescued by pharmacological inhibition of CDK5, indicating a role of Prr7 protein in the maintenance of excitatory synapses via protection of SPAR from degradation. Together, our findings highlight a novel HSD mechanism in which chronic activity leads to miR-329– and miR-495–mediated Prr7 reduction upstream of the CDK5-SPAR pathway.
DTMF-based load control system
Authors: Rahul Pandey , Vikas Kumar Sahu , Sandeep Kumar Dehuri , Piyush Sahu
Published: September 2022

The aim of this paper is to create a remote-controlled home automation system using a mobile phone. One of the newest trends in home appliance control is home automation. Traditional wall switches are located throughout the home and must be physically pressed to turn ON or OFF loads. It is extremely difficult for the elderly or disabled. This technology is designed to enable mobile phone users to control home appliances by dialing a specific number. The advantage of the Dual-Tone Multi-Frequency (DTMF) system is that it can be controlled remotely from a distance, which reduces the burden on a person. Two mobile phones make up a DTMF based system, one phone serves as a remote control and the other as a receiver. Unlike conventional infrared and Radio Frequency (RF) controllers, it may be used to switch devices from anywhere. The device has an MT8870 DTMF decoder, which decodes DTMF tones. This proposed system gives a new direction to the development of home automation.
ОСОБЕННОСТЬ И ПРЕИМУЩЕСТВА ИННОВАЦИОННОЙ ПАРАДИГМЫ БЮДЖЕТНО-НАЛОГОВОЙ СИСТЕМЫ
Authors: Павлов Вячеслав Иванович , Зоидов Хуршеджон Кобилджонович
Published: September 2022

Цель работы. В статье обосновывается особенность новой бюджетно-налоговой системы как приоритета развития электроэнергетики и преимущества перед традиционной бюджетно-налоговой системой, особенно в период существенного ограничения международной торговли из-за широкомасштабных санкций США, стран ЕС и других стран, поддерживающих политику США. Метод и методология работы. В процессе исследования использованы методы эволюционно-институциональной теории, эконометрического моделирования и аналитической оценки. Результаты и выводы. Внедрение инновационной парадигмы бюджетно-налоговой системы можно отнести к импортозамещению, так как действующая в настоящее время налоговая система заимствована из зарубежных стран с российской спецификой НДФЛ со ставкой доходов 13 % и дополнительной ставкой 2 % с превышающих 5 млн рублей в год морально устарела. Инновационная парадигма бюджетно-налоговой системы, используя минимальное количество исходной информации и возможности использования инструментов государственной казначейской системы и цифровизации, ликвидирует базу для коррупционных структур и наполнений бюджетов всех уровней исполнительной власти в объемах, необходимых для выполнения ими своих функций. Область применения результатов. Результаты исследования могут быть использованы органами власти России для ликвидации существующих проблем в области обеспечения экономической безопасности, при реализации структурных реформ, реформы системы государственных финансов, изменении налоговой политики.
ИНВЕСТИЦИОННОЕ РАЗВИТИЕ РЕГИОНОВ СКФО: СПЕЦИФИКА И ПЕРСПЕКТИВЫ
Authors: Арсланов Шамиль Джавадович
Published: September 2022

Цель исследования состоит в исследовании специфики и перспектив инвестиционного развития субъектов СКФО. Методология исследования основана на корректном использовании методов анализа и синтеза, а также систематизации, сравнения, экономического и логического анализа. Результаты. Определены и обоснованы основные негативные тенденции, формирующие комплекс недостатков/барьеров, характерных для сферы инвестиционного развития субъектов СКФО. Выявлены основные направления развития и государственной поддержки конкурентных преимуществ регионов СКФО, определена взаимосвязь высоких инвестиционных рисков и низкого индекса цифровой жизни в субъектах СКФО. Выводы. Современное социально-экономическое и инвестиционное развитие субъектов СКФО помимо традиционных форм государственной поддержки должно опираться и на перспективные экспериментально-инновационные механизмы формирования/привлечения/размещения финансовых и инвестиционных ресурсов, базирующийся на цифровых продуктах.
ФАКТОРЫ, ВЛИЯЮЩИЕ НА КАЧЕСТВО КАДРОВОГО ПОТЕНЦИАЛА
Authors: Саругланов Адил Нисредович
Published: September 2022

В статье рассмотрены теоретические и методические аспекты формирования кадрового потенциала с учетом влияния факторов внешней и внутренней среды. Целью статьи является исследование вопросов, связанных с влиянием различных факторов на формирование и использование кадрового потенциала в современных условиях. Исходя из цели задачи включают рассмотрение сущности кадрового потенциала, основных факторов влияния и способов его повышения. В ходе исследования были изучены учебные пособия, монографии и периодические издания по вопросам формирования и управления кадровым потенциалом. В статье рассмотрено понятие «кадровый потенциал», описаны основные факторы влияния на его качество, подходы к анализу и типовые меры по повышению. Представленный в статье материал помогает выявить проблемы и направления, требующие наибольшего приложения усилий по восполнению имеющихся пробелов в управлении кадровым потенциалом организации.
ФОНДОВЫЙ РЫНОК РОССИИ В УСЛОВИЯХ САНКЦИЙ
Authors: Лунева Марина Викторовна
Published: September 2022

В данной статье проводится анализ проблемы влияния западных санкций в отношении России, их влияние на финансовую систему страны, в частности в какое положение привели санкции фондовый рынок Российской Федерации. В ходе проведенного анализа делаются аргументированные выводы в отношении перспективности развития фондового рынка России, оценивается результативность используемых Минфином инструментов вывода финансовой системы из кризиса.
Changing epidemiology of Salmonella Enteritidis human infections in the Netherlands and Belgium, 2006 to 2019: a registry-based population study
Authors: Chanamé Pinedo Linda , Franz Eelco , van den Beld Maaike , Van Goethem Nina , Mattheus Wesley , Veldman Kees , Bosch Thijs , Mughini-Gras Lapo , Pijnacker Roan
Published: September 2022

Background

Salmonellosis remains the second most common zoonosis in the European Union despite a long-term decreasing trend. However, this trend has been reported to have stagnated in recent years, particularly for Salmonella enterica serotype Enteritidis (SE).

Aim

To describe temporal changes in the incidence of SE human infections, and in its associated factors between 2006 and 2019. In addition, we aim to determine which factors influenced the stagnated trend seen in recent years.

Methods

Data on culture-confirmed SE human infections from national surveillance registries in the Netherlands and Belgium between 2006 and 2019 were analysed using multivariable negative-binomial regression models with restricted cubic splines.

Results

SE incidence was significantly higher in summer and autumn than winter, in persons aged 0–4 years and 5–14 years than in persons ≥ 60 years, and increased with increasing proportions of travel-related and resistant SE infections. SE incidence decreased significantly in both countries until 2015, followed by an increasing trend, which was particularly pronounced in the Netherlands. Potential SE outbreaks in both countries and invasive infections in the Netherlands also increased after 2015.

Conclusion

The increase in potential outbreaks and invasive infections since 2015 may partially explain the observed reversal of the decreasing trend. While these results provide insights into the possible causes of this trend reversal, attention should also be given to factors known to influence SE epidemiology at primary (animal) production and pathogen genomic levels.
ALEXEY BOGOLYUBOV IN THE NAVAL SERVICE, 1841–1853
Authors:   The State Museum-reserve “Tsarskoye Selo”, Guseva Ksenia S.
Published: September 2022

The article considers the period of the making of A.P. Bogolyubov as a painter. After graduating from the Naval Cadet Corps, A.P. Bogolyubov begins his service in the Navy; simultaneously he gets increasingly interested in drawing. For a young officer, it was just a hobby at first; but in 1849, on board the steam frigate Kamchatka, en route from Kronstadt to Madeira, there happened A.P. Bogolyubov’s fateful meeting with Duke Maximilian of Leuchtenberg, President of the Academy of Arts. The Duke praised Bogolyubov’s works and gave him a recommendation to become a professional artist. From that moment on, A.P. Bogolyubov definitely decided to take a new path for himself. He entered the Academy of Arts in 1850, and then, in 1853, left the service in the Navy. Impressed by the naval service, the artist made up his mind to choose subsequently marine painting. On September 24, 1853, the Council of the Imperial Academy of Arts decided to award a large gold medal to Bogolyubov, and that allowed him to do what he really loved. Based on the archival documents, the article describes the key events in the biography of A.P. Bogolyubov; those events made it possible for the artist to leave the naval service and devote himself to art.
NEW TEXTBOOK ON THE HISTORY OF RUSSIA IN THE 18TH CENTURY.KURUKIN I.V., ANTONOVA E.A. RUSSIAN HISTORY. CENTURY 18TH. TUTORIAL. M.: RGGU, 2021. 311 P.
Authors:   Russian State University for the Humanities, Sanin Oleg G. , Kuznetsova Anna A. ,   Russian State University for the Humanities,
Published: September 2022

This review is devoted to the analysis of a new textbook on the history of Russia in the 18th century, published in 2021 at the Russian State Humanitarian University. under the authorship of the teachers of the Department of the history of Russia in the Middle Ages and Modern Times of the faculty of history of the IAI RSUH, professor I.V. Kurukin and associate professor E.A. Antonova. The review emphasizes the importance of this manual for the organization of the educational process at the RSUH, notes the fact that it reflects the latest achievements of Russian historical science in the study of the 18th century. The appearance of this manual is especially necessary to provide students with the opportunity to independently study the disciplines of national history. It is noted that facing the reduction of the academic hours in historical curriculum observed in recent years, the students are forced to solve many issues and problems related to the study of national history on their own. Thus, the issue of providing the educational process with high-quality and modern textbooks containing not only reference and informative material, but also the necessary tools for testing knowledge is acute. Educational publication of I.V. Kurukin and EA. Antonova thereby contributes to the intensification of learning – on the one hand, and on the other – to rising envolvement in the learning process itself. The review provides a brief analysis of the scientific path of the authors of the manual – I.V. Kurukina and E.A. Antonova, their most important scientific monographs and publications of articles are mentioned. In addition, a detailed analysis of the structure and specifics of this manual is given; its numerous advantages and some shortcomings are indicated.
ARCHIVAL FUND OF THE RUSSIAN FEDERATION. WHAT WILL WE BE ABLE TO SAVE? (ON THE EXAMPLE OF THE FUND OF THE A.S. POPOV OMSK RADIO FACTORY)
Authors:   Historical Archives of the Omsk region, Chekalina Lyudmila A.
Published: September 2022

The article presents an overview of the archival fund documents in one of the largest and successfully developing enterprises of the Russian radio equipment industry, the Omsk A.S. Popov Radio Factory, stored in the Historical Archives of the Omsk region (GIAOO). The documents contain the information about the history of the factory and its participation in the socio-economic development of the region. They reflect the features of the state policy, the management system, and the labor relations in the second half of the twentieth century. These materials can be used by researchers in the fields of economic and social history, regional studies, local history, practical genealogy. The management of the enterprise, which had become a non-state one enterprise, initiated its removal from the list of organizations – the sources of the GIAOO acquisition, and the replenishment of the archival fund stopped. The main purpose of the article is that by following the experience of the relationship between GIAO and the A.S. Popov Omsk Radio Plant to substantiate the insufficient efficiency of the interaction mechanisms between archival institutions and non-state organizations in the formation and preservation of the Archival Fund of the Russian Federation, as the main source of valuable reliable information on regional and national history. Empirical and problematic research methods were used for preparing the article. The author comes to the conclusion that it is necessary to improve the current legislation in terms of regulating the relationship of the subjects in the field of archiving – the subjects representing public and private interests.
Akıllı Liman Yapılanmasına Yönelik Uygulamaların Bilinirliği Üzerine Keşfedici Bir Araştırma
Authors: GÜRSOY İpek , HATUNOĞLU Zeynep
Published: September 2022

Uluslararası ticaret açısından önemli bir pazarlama kanalı olan limanlar, ülkelerin ekonomik gelişmişlik düzeylerinin en önemli belirleyicilerinden birisidir. Dünya ticaretinin %90’ının denizyolu üzerinden gerçekleşmesi, günümüz lojistik zincirinin en önemli öğelerinden birisi olarak ifade edilen limanların önemini gittikçe artırmakta ve limanlarda dijital dönüşümü gerekli kılmaktadır. Artık hemen her sektörde kendisini gösteren Endüstri 4.0 teknolojilerinin limancılık sektöründe de kullanılmaya başlanması, akıllı alt yapılar, nitelikli işgücü ve otomasyonun entegrasyonu olarak ifade edilen akıllı liman kavramını da gündeme getirmektedir. İlgili literatür incelendiğinde, son yıllarda limancılık sektöründe dijitalleşme uygulamalarının incelenmesine yönelik çalışmaların mevcut olduğu görülmektedir. Ancak henüz Türkiye’deki limanların akıllı liman olma yolundaki girişimlerinin operasyon, çevre, enerji, emniyet ve güvenlik boyutlarıyla araştırıldığı bir çalışmaya rastlanılamamıştır. Bu çalışma ile birlikte, limanlarda faaliyet gösteren personellerin belirtilen dört boyut altında yer alan uygulamalara yönelik bilgi düzeyleri araştırılmıştır. Keşfedici nitelikte olan bu araştırmada, örneklem yöntemi olarak amaçlı örnekleme; veri toplama yöntemi olarak yüz yüze anket ve çevrimiçi ortamda hazırlanan anket formu kullanılmıştır. Toplanan veriler IBM Statistics 25 istatistik paket programı yardımıyla analiz edilmiştir. Araştırma sonucunda, akıllı liman yapılanmasına yönelik teknolojilerin bilinirlik düzeylerinin düşük olduğu tespit edilmiştir.
Early Complications after Limb Salvage Procedures: Prospective Cross Sectional Study
Authors: Ali Ziad , Saeed Javeria , Umer Masood
Published: September 2022

ABSTRACT

Introduction:

Sarcomas are tumors that are mesenchymal in origin involving bone and soft tissues occurring in all age groups. Giant cell tumor, although benign, is locally aggressive and can also destroy the bone. Amputation was once considered primary treatment but now with advancements in diagnostic imaging modalities, surgical procedures and adjuvant therapies, limb salvage surgeries have become the preferred treatment modality.

The primary objective of our study was to determine the incidence of early complications occurring within the first thirty days in patients who underwent limb salvage surgery at our hospital. The secondary objective was to assess the association of these complications with patient-related factors, surgical modality, tumor characteristics and neoadjuvant therapy.

Methodology:

All the patients with bone or soft tissue sarcoma and aggressive giant cell tumors of the extremities who underwent wide excision and limb salvage surgery from February 2020 to December 2021 were included in this study. Data were collected prospectively on follow-up visits in the clinic for one month. Data were compiled and analyzed using SPSS version 22. A p-value of <0.05 was considered significant throughout the study.

Results:

A total of 60 patients were included in this study. The mean age of the patients was 39.90 years. Bone and soft tissue tumors were found in 35 and 25 patients respectively. A total of 13 patients experienced postoperative complications within 30 days of surgery. The association of these postoperative complications with gender distribution, prior comorbid conditions, type of tumor, anatomical location of the tumor and neoadjuvant therapy was found to be statistically insignificant.

Conclusion:

The most frequently occurring postoperative complications are wound-related and the incidence of these complications is independent of the proposed risk factors.

Research registry number:

Researchregistry4695.

Highlights
Investigation of User Trends and Recreational Service Relations in the Sample of Kadınçayırı Natural Park
Authors: AMUCAOĞLU Ayşe , TÜLEK Betül , AYTAŞ İbrahim
Published: September 2022

With the increasing interest in outdoor recreation activities, the demand for national parks and natural parks also increases. Natural parks are natural parts with vegetation and wildlife features, suitable for public recreation and entertainment in the integrity of the landscape. Unlike National Parks, they are natural parts that have protection, recreation and tourism areas with only natural resource values that are rare nationally and internationally. Today, natural park areas are visited by many people who come for recreation activities. For this reason, recreational activities in natural parks gain importance and take an important place in tourism activities. Kadınçayırı Natural Park, which is the research area, is located between Çankırı and Kastamonu provinces. It has aimed to reveal the recreational potential by evaluating user trends and expert preferences with the surveys conducted in the field. Analytical Hierarchy Process (AHP) analysis has been applied to the obtained data arranged in line with Gülez Method features and it has been determined that the recreational service and potential of the Kadınçayırı Natural Park showed enrichment and there are some criteria that affect the recreational activities in the area and in this context, suggestions have been developed in terms of the Landscape Architecture professional discipline.
A review: Effect of planting distances on some sunflower cultivar’s quality
Authors: Shathar Abdulhamza. Alaamer  , Salih Kadhum. Alwan Alsharifi  , Naim Shtewy
Published: September 2022

The influence of planting distances (PD) on growth of sunflower (Helianthus annuus L) yield, for two cultivars of Euroflor (EU) and Peredovick (PE), were tested at three PD of 20, 25 and 30 cm. The experiments were conducted in a factorial experiment under complete randomized design with three replications. The results showed that the EU cultivar was significantly better than the PE in all studied conditions. The RL, RDFW, PDFW, SD,LA,Sl and BY , 22.524 cm , 149.635g, 182,091g 36.70 mm, 7776 cm2, 19.91mm and 7.215 t.ha-1, the treatment of PD of 30 cm was significantly superior to the levels of 20 and 25 cm in all studied conditions.