bluuebunny/crossref_metadata_2025 huggingface dataset:
CORRELATION BETWEEN HEPATIC STEATOSIS AND LIVER FIBROSIS WITH CAROTID INTIMA-MEDIA THICKNESS AND CAROTID PLAQUES IN PATIENTS WITH NON-ALCOHOLIC LIVER DISEASE
Authors: Tran Thi Khanh Tuong , Huynh Minh Duc , Tong Nguyen Diem Hong
Published: December 2023

Background: Nonalcoholic fatty liver disease (NAFLD) is currently the leading cause of chronic liver disease. Approximately 10 to 30% of patients with NAFLD progress to Nonalcoholic steatohepatitis (NASH). NASH can lead to liver fibrosis, progression to cirrhosis and hepatocellular carcinoma, and eventually death. In addition, NAFLD also increases the risk of cardiovascular diseases such as angina, myocardial infarction and stroke 1.64 times higher than patients without NAFLD. Determining the correlation between NAFLD and carotid intima-media thickness will indirectly contribute to demonstrating the association between NAFLD and cardiovascular risk factors. Objectives: Determine the proportion of NAFLD patients with carotid intima-media thickness (CIMT) ≥ 0.8 mm. Investigation of the correlation between the hepatic steatosis and liver fibrosis by FibroScan - CAP with CIMT in NAFLD patients. Determination of predictive risk factors of CIMT ≥ 0.8 mm in NAFLD patients. Method: Prospective study on 182 NAFLD patients aged 18 years and older who visited Dai Phuoc General Clinic from January 2023 to June 2023. Results: The proportion of NAFLD patients with CIMT ≥ 0.8 mm was 45.1%. The proportion of NAFLD patients with carotid atherosclerosis was 44.0%. There was a positive, strong correlation (r = 0.61) between the hepatic steatosis measured by FibroScan - CAP and CIMT in NAFLD patients. There is a positive, weak correlation (r = 0.37) between liver fibrosis measured by FibroScan and CIMT in NAFLD patients. Age, hypertension, central obesity, and hepatic steatosis were independent risk factors predicting CIMT ≥ 0.8 mm in NAFLD patients. Conclusion: There is a strong positive correlation between the hepatic steatosis measured by FibroScan - CAP and CIMT in NAFLD patients. Carotid doppler ultrasound to measure CIMT, evaluate carotid atherosclerosis should be undergone in NAFLD patients with risk factors such as older age, hypertension, central obesity and  hepatic steatosis.
DIAGNOSTIC MODEL OF TALAROMYCOSIS IN HIV/AIDS PATIENTS
Authors: Vo Trieu Ly , Vuong Minh Nhut , Nguyen Van Vinh Chau , Thuy Le
Published: December 2023

Introduction: Talaromycosis (formerly penicilliosis), one of the most important opportunistic infections in Southeast Asia, is a common cause of HIV-AIDS-associated death. The current diagnosis of Talaromyces marneffei relies on culture. As microbiological results are often late, taking up to 14 days for pathogens isolation, the mortality rate is high. Serum Mp1p ELISA test was used to determine an earlier diagnosis of Talaromycosis. The research objectives were: (1) to determine the cut-off value, sensitivity, and specificity of the Mp1p ELISA test in AIDS patients; (2) to develop diagnostic models (with and without Mp1p ELISA test) of talaromycosis in AIDS patients. Methods: A descriptive cross-sectional study. HIV-infected patients aged ≥18 years with TCD4 <100 cells/mm3 admitted to Ward E, Hospital for Tropical Diseases from June 2017 to July 2019  were recruited. Data analysis using SPSS 25.0 software. A receiver operating characteristic (ROC) curve and Youden index on the ROC curve was used to determine the cut-off value. The area under the ROC curve (AUC) and the 95% confidence intervals (CIs) were used to determine the discrimination power between cases and controls. Chi-square test, odds ratio (OR), and 95% confidence interval were used to find associations among variables. After multivariate analysis, the model of talaromycosis diagnosis was built by Monogram in R.3.6.3 software. Results: 533 patients meeting the inclusion criteria were enrolled. 78.4% were male; the median age was 34 years (IQR: 29-40), and 77.5% were <40 years-old groups. 70 patients diagnosed with Talaromycosis were compared with other opportunistic infected participants (OIs).. The maximum Youden index=0,856 in correlation with the 0,22 OD cut-off value of serum Mp1p presents the highest sensitivity and specificity, with SEN = 88.6% and SPE = 97.0%, respectively. Two models (with and without serum Mp1p) were built based on the adjusted OR of risk factors. Two models based on living areas, skin lesions, low platelet, and Mp1p result. The two models have high accuracy in diagnostic talaromycosis. The SEN and SPEC of the model without Mp1p were 68.6% and 98.1%, and the SEN and SPEC of the model with Mp1p were 85.7% and 98.7%. Recommendation: Serum Mp1p ELISA as well as  Diagnostic models of talaromycosis are considered as novel tools for early diagnosis of Talaromycosis in AIDS patients.
SPECIFIC COMPETENCIES REQUIRED OF ONCOLOGY NURSES IN VIETNAM: RECOMMENDATION FOR NURSING EDUCATION
Authors: Do Thi Ha , Khanitta Nuntaboot
Published: December 2023

Background: The oncology nurse plays a critical role in the delivery of quality nursing care to people with life-limiting conditions as they are among the most vulnerable of populations served by health services. Purposes: The study aims to explore needed competencies among nursing practicing in oncology facilities in hospital. Methods: An ethnography study was conducted in Ho Chi Minh City, Vietnam with a purposive sample of fifteen participants, including oncology nurses, nurse managers, medical doctors, and family relatives of patients with cancer. Data collection was by participant-observation, in-depth interviews and focus group discussions. Content analysis was used to analyze the data. Findings: Besides providing the regular nursing care as general nurses, nurses working in oncology settings response to specific services including end of life nursing care. Specific competencies among oncology nurses include Knowledge on science of cancer and complementary therapies; Understanding and sensitive on cultural and vulnerable groups; Knowledge and skills on palliative care and hospice; Special communication skills in vulnerable environment; and Specific essential characteristics requirement among oncology nurses. Conclusion: The knowledge generated would benefit nursing managers, nursing educators, and other significant personnel to pursue effective competency development strategies to nurses in order to achieve a high standard of nursing care in oncology settings.
INVESTIGATION OF EXON20 PIK3CA GENE MUTATION IN PLASMA OF HORMONE RECEPTOR POSITIVE BREAST CANCER PATIENTS
Authors: Dinh Thi Thao , Nguyen Phu Thanh , Dong Van Quyen , Ly Tuan Khai , Le Huu Song , Ngo Tat Trung
Published: December 2023

Objective: To determine the frequency of H1047R mutation on exon 20 PIK3CA gene in the plasma of hormone recepter positive (HR+) breast cancer (BC) women and its relationship with clinical characteristics of these patients. Subjects: Plasma was separated from venous blood of 141 female HR+ BC patients, have been treating at 108 Military Central Hospital from June 2021 to June 2023. Method: Circulating free DNA (cfDNA) was isolated from plasma by magnetic beads (Thermo Fisher Scientific). The H1047R hotspot mutation on exon 20 PIK3CA gene was detected in 141 plasma samples by an in-house Realtime PCR assay using a wild-type allele-specific blocker. Results: 47/141 samples (33,3 %) had the H1047R mutation. The H1047R mutation was present in all disease stages, both in metastatic and non-metastatic cases. Although, the rates of gene mutation in late-stage, metastatic cancer patients were higher than those in the early-stage, non-metastatic cancer group, there was no statistically significant difference between the two groups (p > 0.05). Whereas it was not linked to other clinical traits of patients with HR+BC, the H1047R mutation was more common in those with liver metastases and in those received Fulvestrant (p < 0.05). Conclusion: Peripheral blood from patients with HR+BC in all stages contained the H1047R mutation on exon 20 of the PIK3CA gene. This mutation frequently developed in patients received Fulvestrant treatment and has been related to liver metastases.
STRATEGIES TO RESPONSE TO PSYCHOLOGICAL TRAUMA OF HEALTHCARE WORKERS IN VIETNAM DURING THE COVID-19 PANDEMIC: IMPLICATION FOR THE FUTURE
Authors: Do Thi Ha , Huynh Tan Son , Nguyen Thanh Hiep , Luu Nguyen Duc Hanh , Tran Thuy Khanh Linh
Published: December 2023

The COVID-19 pandemic has brought great challenges and stress to healthcare workers (HCWs). The application of appropriate strategies to respond to psychological trauma contributes to the protection of HCWs’ well-being. The objective of this study is to discover the strategies that HCWs used for psychological trauma coping during their participation in COVID-19 prevention and control. This is a qualitative study, conducted in Ho Chi Minh City (HCMC), Vietnam, collecting information by in-depth interviews with 40 HCWs participating in COVID-19 prevention and control in HCMC in 2021. Findings showed that strategies of stress coping that HCWs used in the pandemic management are diverse. There were six main themes identified as positive coping solutions in this study including rest and entertainment activities; improving the working environment; maintaining social interaction; positive thinking and action; strengthening personal coping capacity; and showing professionalism at work. In addition to these positive coping solutions, some participants expressed that they have used negative coping skills including using stimulants; taking their anger out on others; running away from work; refusing contact with others; surrendering to their own fate; and quitting their jobs. In addition to general solutions, the participants in charge of different working groups had some specific solutions to deal with the psychological trauma.
Enhancing Symbolic Manipulation through Pairing Primitive Recursive String Functions and Interplay with Generalized Pairing PRSF
Authors:   Dr. Ambedkar Institute of Technology for Handicapped, Dubey ShivKishan ,   Harcourt Butler Technical University, Kohli Narendra ,   Dr. Ambedkar Institute of Technology for Handicapped; Harcourt Butler Technical University
Published: December 2023

In earlier studies, the notion of generalized primitive recursive string functions has been presented, and their connections with abstract paring-based primitive recursive string functions have been investigated. Our study is centered around establishing a fundamental theorem that states a connection between these two distinct sorts of functions. The theorem specifically establishes that the universal definition of every generalized pairing primitive recursive string function is contingent upon its correspondence with a conventional(abstract) pairing primitive recursive string function. This article introduces innovative concept of Pairing Primitive Recursive String Functions (P-PRSF) for manipulating and interacting with word pairs. Based on the principles of primitive recursion and pairing functions, P-PRSF enables the extraction, transformation, and combination of word components. The proposed theorems validate the effectiveness of P-PRSF in capturing relationships within word pairs. Moreover, the interplay between P-PRSF and Generalized Pairing PRSF (GP-PRSF) extends the concept to involve more intricate interactions.
Microangiopathic Haemolytic Anaemia Induced by COVID-19
Authors: A Niblock  , Chikanya Nyasha
Published: December 2023

Microangiopathic Haemolytic Anaemia (MAHA) is a descriptive term for the presence of fragmentation of red cells (schistocytes) which can be demonstrated on a blood film [1]. It occurs when endothelial damage and/or fibrin deposition damages red cells. The presence of this associated with a thrombocytopenia is an emergency as the known differential includes DIC, TTP, HUS, Malignancy, and HELLP all of which can ultimately end life [2]. Since Covid19 pandemic we report another case in this differential that resolves with conservative management.
TB NOTIFICATION IN CHILDREN: THE EXPERIENCE OF TARGETED COMMUNITY DEMAND CREATION AMIDST INSECURITY IN IMO STATE, NIGERIA
Authors: Arinze Emmanuel Ajogwu  , Ikeru Adaeze  , Maryann Amaechi  , Jude A. Ilozumba  , Chukwuebuka Ugwu  , Susilo Wulan  , Uzoma Chidinma Ajegbo  , Obioma Chijioke-Akaniro
Published: December 2023

This paper explores the challenges and successes of tuberculosis (TB) notification in children amidst a backdrop of insecurity in Imo State, Nigeria. Emphasizing targeted community demand creation strategies, the study investigates the intricate relationship between insecurity, community engagement, and pediatric TB detection. Drawing upon a comprehensive literature review, this research delves into the epidemiology, diagnosis, and treatment of TB in children, the ramifications of insecurity on healthcare access in Imo State, and effective community engagement strategies in healthcare initiatives. The literature findings underscore the substantial burden of TB among children and the distinct hurdles faced in environments characterized by insecurity. The prevailing insecurity in Imo State significantly disrupts healthcare services, leading to delays in TB diagnosis and treatment initiation. Nevertheless, the review identifies community engagement approaches as a promising avenue for bolstering TB notification rates in pediatric populations. These approaches empower local communities to actively participate in the identification and management of TB cases, ultimately contributing to the enhancement of pediatric TB notification. A conceptual framework, derived from amalgamated literature, elucidates the intricate interplay between insecurity, community engagement, and TB notification. This study highlights the pivotal role of community-driven interventions in mitigating the challenges posed by insecurity in Imo State, Nigeria, and presents actionable recommendations for the development of healthcare policies and programs tailored to the region. This research not only augments our comprehension of TB notification among children within insecure contexts but also provides valuable insights into the broader domain of community-based healthcare interventions. It underscores the exigency for customized strategies to address TB in pediatric populations in regions marked by insecurity, ultimately contributing to the amelioration of health outcomes for children in Imo State, Nigeria, and analogous settings

Keywords:  TB, Children, Community, Nigeria.
Performances of Some Perennial Legume and Grass Mixtures under Rainfed Conditions of a Continental Climate Region
Authors: YAVUZ Tamer , KIR Hakan
Published: December 2023

Forage yield and the quality of the pastures in Turkey, especially in Central Anatolia, where the continental climate is dominant, are very low, and their vegetation is degraded to a great extent due to use without proper management practices. The inadequacy of the forage crop production in agricultural land and the low yield and quality of forage are among the main problems of husbandry. The present study aimed to determine perennial legume and grass mixtures with high forage yield and quality under rainfed conditions of the continental climate region in Turkey. The experimental design was randomized blocks with three replications. In the experiment, smooth brome (SB), intermediate wheatgrass (IW), alfalfa (A), sainfoin (S), and lesser burnet (LB) were sown as pure and mixed in different ratios. Two years averaged values of dry matter yield and crude protein, Acid Detergent Fiber (ADF), and Neutral Detergent Fiber (NDF) contents of dry matter varied between 2613 and 6268 kg ha-1;118 and 205 g kg-1; 249 and 424 g kg-1, 416 and 558 g kg-1, respectively. Higher dry matter yields were obtained from A+S+IW+SB, S+LB+IW+SB, A+LB+IW+SB, S+IW, and A+IW+SB mixtures. The pure sowings of the SB, IW, and LB gave lower dry matter yields than the mixtures. Crude protein contents of alfalfa and sainfoin were higher than other pure sowings and mixtures. The ADF and NDF contents of mixtures were higher than those of pure sown of alfalfa, sainfoin, and lesser burnet, they were lower than those of IW and SB. In terms of dry matter yield, crude protein yield, ADF and NDF content, A+S+IW+SB, A+LB+IW+SB, and S+LB+IW+SB mixtures were superior to other mixtures and pure sowings. Alfalfa may be predominant in mixtures over time, and animal health problems may occur under grazing conditions. Therefore, the mixtures of A+S+IW+SB and A+LB+IW+SB can be recommended for mowing, while the S+LB+IW+SB mixtures can be recommended for grazing.
Abordagens em medicina: ciência e prática
Authors: Figueiredo Bárbara Queiroz de , Brito Emilayne Nicácio Dias , Araújo Ana Paula Ferreira , Oliveira Laura Santos , Amaral Francyele dos Reis , Corrêa Bernardo Augusto Silveira , Rodovalho Júlia Pereira , Pereira Amanda Káren Alves , Nogueira Eduarda Canedo , Freitas Maria Laura Alves , Almeida Pedro Henrique Ribeiro de
Published: December 2023

A publicação de um artigo científico ou técnico é uma forma de transmitir à comunidade técnico-científica o conhecimento de novas descobertas, e o desenvolvimento de novos materiais, técnicas e métodos de análise nas diversas áreas da ciência. Sob essa perspectiva, o Diretório Acadêmico Dr. Fued Elias Esper, do Centro Universitário de Patos de Minas (UNIPAM), junto às ligas acadêmicas da instituição, promovemos a 2ª edição deste livro que contou com mais de sessenta obras de alunos.
UMA ANÁLISE ACERCA DA LEGALIDADE NA INDUÇÃO DE CICLOS REPRODUTIVOS EM ANIMAIS DE CANIS COMERCIAIS
Authors: Santos Thiago Davi Bastos dos
Published: December 2023

O presente trabalho tem como objetivo realizar uma análise acerca da legalidade da indução de ciclos reprodutivos em animais de canis comerciais, bem como a questão dos maus-tratos de animais, reunindo e apresentando a legislação existente que vigora no país com intento de propiciar o amparo legal aos animais. Com base na análise das leis mais importantes sobre o assunto, demonstra-se a mudança da mentalidade da sociedade acerca dos animais, e a consequente evolução ao longo do tempo da legislação disposta sobre eles. Aponta-se também a necessidade da imputação de penas mais rigorosas ante determinadas práticas criminosas, além de uma fiscalização exercida com maior eficiência, para que haja, de maneira veraz, uma proteção àqueles que não podem falar. Ademais, na legislação há uma grande lacuna, visto que, não existe uma lei nacional que regulamente os parâmetros que devem ser observados pelos criadores de cães ou gatos de raça, assim como para a procriação e venda de filhotes. Contudo, a própria população, com movimentos sociais protecionistas movimentados através da internet e das redes sociais, tem disseminado conhecimento e alertado a todos sobre os canis, o que gerou significativo aumento na quantidade de denúncias, suprindo a lacuna legislativa. As técnicas utilizadas para a coleta de dados na presente pesquisa e análise, foram a revisão bibliográfica, a coleta de doutrinas e leis. Por fim, conclui-se que os canis clandestinos são um problema na sociedade brasileira, mas que podem ser combatidos através da conscientização pública.
O USO INDISCRIMINADO DE ANABOLIZANTES
Authors: Lima Carlos Alexandre de , Baiense Alex Sandro Rodrigues , Andrade Leonardo Guimarães de
Published: December 2023

A testosterona é um hormônio androgênico anabolizante endócrino, porém existem esteroides anabolizantes sintéticos produzidos a partir do hormônio masculino, a testosterona. Nas últimas décadas essas substancias vêm sendo utilizadas por frequentadores de academias de forma indiscriminada, levando assim a uma preocupação da saúde pública devido aos seus efeitos colaterais, muitas vezes irreversíveis. Este trabalho tem como objetivo geral realizar uma revisão sistemática sobre as consequências negativas do uso indiscriminado de anabolizantes. A metodologia utilizada foi a de revisão bibliográfica da literatura, com base nos anos de 2020 a 2023. Pode se concluir que os sistemas do organismo mais acometidos pelo uso inadequado são o reprodutivo, hepático, musculoesquelético, endócrino, renal, cardiovascular, dermatológico e neuropsiquiátrico, além de interferir no comportamento dos usuários.
A ATUAÇÃO DA FISIOTERAPIA PÉLVICA NO TRATAMENTO DA DISFUNÇÃO ERÉTIL: UMA REVISÃO INTEGRATIVA
Authors: Silva Mirelle Ferreira Lisboa da , Gresik Karla Rocha Carvalho
Published: December 2023

Introdução: Esta pesquisa trata-se de uma revisão integrativa da literatura com o objetivo geral de identificar a eficácia das condutas fisioterapêuticas no tratamento da disfunção erétil (DE). A pesquisa consistiu em uma revisão da literatura com artigos publicados entre os anos de 2001 a 2021, as buscas pelos artigos foram realizadas nos principais bancos de dados online, Pubmed, BVS, SciELO e PEDro. Os achados apontam que a fisioterapia pélvica possui condutas fisioterapêuticas eficazes para o tratamento da DE, a exemplo de abordagens eletroterápicas e cinesioterapêuticas, sendo necessário mais estudos específicos para um protocolo adequado intervindo prioritariamente na causa do problema.
TRIBUTAÇÃO AMBIENTAL E A PROTEÇÃO DO MEIO AMBIENTE
Authors: Mota dos Santos Karina , Santos Jackson Novaes , Santos Dartagnan Plínio Souza
Published: December 2023

O presente estudo objetiva abordar aspectos acerca da Tributação Ambiental como mecanismo de proteção ao Meio Ambiente. A importância do estudo se fundamenta na crescente utilização dos recursos naturais nas atividades econômicas, que por muitas vezes ocorrem de forma desenfreada e desnecessária, resultando na degradação do ecossistema, criando-se assim, a necessidade de implementação de métodos que se adequem ao atual cenário brasileiro. Deste modo, o Estado, através da Tributação Ambiental, pode estimular condutas positivas dos contribuintes utilizando-se dos benefícios fiscais, ou desestimulando as condutas que degradam o meio ambiente, atribuindo aos contribuintes a responsabilidade por suas condutas negativas. O Tributo Ambiental tem efeito extrafiscal, visto que objetiva regular a atuação do contribuinte. Utilizou-se da pesquisa qualitativa descritiva, assumindo a forma de pesquisa bibliográfica. Utiliza o método de abordagem dedutivo. Visou-se averiguar a efetividade da tributação ambiental pátria como método de incentivo na preservação do meio ambiente e analisar o conflito entre a ordem econômica tributária e ambiental. Conclui que o tema é de suma importância para a compreensão de que é dever do Poder Público e da coletividade em termos de preservação do Meio Ambiente para as futuras gerações, com escopo no acesso ao meio ambiente ecologicamente equilibrado, direito fundamental e irrevogável, indelevelmente associado ao contexto da “tributação ambiental”.
COMBATE À HIPERTENSÃO ARTERIAL: IMPORTÂNCIA DA PREVENÇÃO E DO CUIDADO AO IDOSO
Authors: Pereira Michael da Silva , Andrade Leonardo Guimarães de
Published: December 2023

A hipertensão arterial sistêmica (HAS) é uma doença muito comum que constitui um importante problema de saúde pública no Brasil e no mundo, sendo um fator de risco para o desenvolvimento de doenças cardiovasculares, cerebrovasculares e renais, além de ser uma importante causa de morte para muitas pessoas. Tendo como, objetivo analisar o que está sendo feito atualmente para combater a HAS, desde a conscientização e prevenção até o atendimento aos pacientes idosos que já possuem a doença, a partir da leitura das evidências científicas. Sendo assim, foi realizada uma revisão abrangente da literatura que sintetiza o conhecimento e incorpora a aplicabilidade prática de importantes resultados de pesquisas. Foram adotados, a busca de evidências realizada no Portal de Periódicos da Capes/MEC, na área de conhecimento que foi Ciências da Saúde, os fundamentos foram: Science Direct e SCOPUS. Além disso, foram realizadas buscas na Biblioteca Eletrônica de Ciências Online (SciELO Brasil); na Biblioteca Virtual em Saúde (BVS), abrangendo as seguintes bases de dados: Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e MEDLINE. Também na Biblioteca Nacional de Medicina (Pubmed) e na Biblioteca Cochrane.Com os descritores em Ciências da Saúde (DeCS/MeSH), Português: Hipertensão Arterial; Prevenção; Cuidados ao Idoso. Entretanto, a maioria dos pacientes idosos com hipertensão arterial sistêmica desenvolve complicações decorrentes do tratamento inadequado, predispondo-os a outras comorbidades. As doenças cardiovasculares são a principal causa de morte no Brasil e a hipertensão é um dos principais fatores de risco. A hipertensão arterial sistêmica é um problema de saúde pública cujo controle contínuo visa prevenir alterações irreversíveis no organismo e está associada à morbimortalidade cardiovascular. O controle da pressão arterial sistêmica está diretamente relacionado à adesão do paciente ao tratamento. A não adesão à medicação é uma das principais causas do baixo controle da hipertensão e um dos problemas mais importantes enfrentados pelos profissionais da atenção primária.
AVANÇOS TECNOLÓGICOS NA ORTOPEDIA: IMPACTO NO TRATAMENTO DE DISTÚRBIOS OSTEOMUSCULARES
Authors: Oliveira Marcelo Henrique Gomes de , Pessoa Gabriel Braga da Veiga , Santana Marco Aurelio Santos , Mendes Ravi Cavalcanti
Published: December 2023

Este artigo examina de forma abrangente os avanços tecnológicos recentes e seu impacto no tratamento de distúrbios osteomusculares na prática ortopédica contemporânea. A integração da inteligência artificial (IA) na tomada de decisões clínicas emerge como uma peça fundamental, evidenciando sua capacidade de aprimorar a precisão diagnóstica e personalizar planos de tratamento. Tecnologias de imagem avançada, como tomografia computadorizada e ressonância magnética, proporcionam uma visualização tridimensional detalhada, permitindo diagnósticos mais precisos e intervenções cirúrgicas mais eficazes. Além disso, a aplicação de dispositivos robóticos na reabilitação ortopédica destaca-se como um avanço promissor, oferecendo suporte físico personalizado e monitoramento contínuo durante a recuperação pós-cirúrgica. No entanto, desafios éticos, econômicos e logísticos surgem como considerações críticas na adoção generalizada dessas inovações. A discussão equilibrada desses resultados destaca a necessidade contínua de pesquisa para abordar lacunas identificadas e promover uma implementação eficaz dessas tecnologias emergentes. Este estudo contribui para a compreensão atualizada do cenário ortopédico, servindo como um guia para futuras investigações e práticas clínicas mais avançadas
Pazarlamanın “Gümüş Pazarı” Yaşlı Tüketiciler Üzerine Nitel Bir Araştırma
Authors: EROĞLU PEKTAŞ Güzide Öncü
Published: December 2023

Abstract Rapidly flowing time, changing/transforming world and developing technology challenge us in the vital struggle of humanity. In every period of life, people try to keep up with this process and have to follow many parameters such as the global world and business disciplines. While doing this, one must also manage the troubles and difficulties brought by periods such as infancy, childhood and old age. The importance and size of this market of elderly consumers, which has become very popular in recent years and defined as the "silver market" of marketing, has accelerated with the aging of the world population. In this study; using a semi-structured interview form; through analogous sampling, the purchasing behaviors of a total of 9 elderly consumers aged 60 and over were examined in depth using descriptive and content analysis methods. In this regard, when the general outcomes of the study are considered in three themes; In terms of their purchasing behavior, they go shopping alone once a week, on weekdays and weekends; It has been observed that they do not consult the social circle when purchasing products/services from markets and neighborhood markets via credit card. Comparisons are made in terms of product/service usage, taking into account quality, price and similar factors; Priority is given to reliable brands for food, cleaning and health. In terms of the pandemic period, it has been determined that hygiene-mask causes changes in the shopping environment and shyness/fear. In summary, this study; it is important in the marketing sector to increase the awareness of older consumers about their daily life purchasing behavior and to raise awareness of this consumer group. In addition, they were asked questions within the scope of in-depth interview technique with the qualitative research method and the answers to these questions were interpreted. Keywords: Older consumers, Consumer behavior, Purchasing behavior, Silver market, Qualitative research
Eğitim Yönetiminde Kurumsal Çerçevede Örgütsel Adalet Teori ve Yaklaşımlarının İncelenmesi
Authors: DALGA Nehir
Published: December 2023

Organizational justice theories are classified as Adams' equality theory, Deutsch's distribution theory, the justice judicial model developed by Leventhal, Crosby's relative deprivation model, Thibaut and Walker's self-interest model and the group value model. The theory of equality questions whether people have a moral state of the rewards they receive during their perceptions of justice. The concept of equity or equality that makes up the theory consists of distributive justice and mental incompatibility approaches. Observations have been made about the fairness of what employees will receive as a result of their contributions to organizations in the justice judicial model and it has been concluded that this will not be possible under all circumstances. It was argued that it would be fair to obtain the gains deservedly and to create appropriate environments for the needs of employees to be taken into consideration. Distribution theory is related to the distribution of conditions and achievements between individuals that can affect a person's physical, psychological, social and economic status. Decateration theory is related to the distribution of conditions and achievements between individuals. The theory of relative deprivation is a theory that describes a situation experienced by an individual who cannot benefit from equality. In this theory, it refers to the emotion that an individual feels when making contradictory and negative comparisons. According to the control model, individuals' thoughts about the fairness of decisions are a major determinant of the reactions they elicit against the gains they benefit from procedures. In the group value model, it is argued that group interests should take precedence over personal interests. Employees are expected to act together with the group and treat their cats fairly. In this model, individuals want to belong to a group and stay in long-term relationships with their groupmates. Key Words: Educational Institutions, Educational Administration, Organizational Justice
Eğitim Kurumlarında Örgütsel Adalet Algısının Oluşmasında Eğitim Yöneticilerinin Rolünün İncelenmesi
Authors: DALGA Nehir
Published: December 2023

Abstract The relationship between teachers and school management in educational institutions can directly affect the Deciency level of the school. The situation of the teachers in the institution constitutes a decisive influence on the students' performances for the future. The fact that school principals develop a fair management towards teachers, that is, they exhibit a fair attitude in the distribution of merit and equality, will reveal a positive development course in teachers' perceptions of justice towards school management and the institution. The fact that the value of the work that teachers have done in the school is appreciated and respected by the school administration, that is, the output process takes place at the desired stage, creates an indicator of the fair behavior of school principals towards teachers, while at the same time enabling teachers to have more confidence in school principals and, indirectly, in the institution. Maintaining organizational functioning in educational institutions in a fair manner is one of the issues that teachers attach importance to. In the process of making and implementing decisions, the fact that school principals share healthy information with teachers and maintain a transparent management approach has a positive impact on teachers' perceptions of justice. Key Words: Educational Institutions, Organizational Justice, Teacher, Education Administrator
Features of functioning of higher education institutions under martial law through the prism of quality assurance of professional training of future specialists
Authors: Iliichuk Liubomyra
Published: December 2023

The paper deals with the peculiarities of functioning and quality assurance of educational activities of higher education institutions under the conditions of the legal regime of martial law. It was found out that the educational sector has suffered devastating consequences as a result of Russia's full-scale invasion of Ukraine, which consist in colossal losses, material damage and intangible harm, which negatively affects the quality of educational services, and therefore the future professional and scientific potential of the country. The article has outlined the main challenges facing the system of higher education as a result of Russian aggression: destruction of educational infrastructure, a marked limiting of funding, shortage and a sharp reduction of personal potential, decrease in the number of the contingent of applicants for higher education, loss of educational management in the territories that are under temporary occupation or are in the zone of active military operations. The institutional and normative support of the educational process under martial law has been disclosed. According to the key research results the main priorities of higher education institutions in the conditions of war are the creation of a safe educational environment, the introduction of innovative approaches to the organization of the educational process, psychological support for participants in the educational process, the restoration of educational infrastructure, the continuation of intra-system transformative processes in the organization of the educational process and qualitative transformations in the system of internal quality assurance for the provision of educational services to future specialists. Reached conclusions are based on the main transformational changes in the activities of higher education institutions and also on key challenges and ways to overcome them in the context of ensuring the quality of educational services in the war and post-war periods of Ukraine's recovery.
Inclusion in Higher Education Under Wartime: National Level of Regulation and Strategic Development Goals
Authors: Otych Olena , Orzhel Olena
Published: December 2023

The article explores programme documents and strategic goals aiming at enactment of inclusion in higher education at the national level in the context of the existing problems of inclusive education implementation. The content of Ukrainian legislation is examined, namely: The Procedure for Inclusive Education Organization in Institutions of General Secondary Education, The National Strategy for Barrier-Free Environment in Ukraine for the period of 2030; The Strategy for the Development of Higher Education in Ukraine for 2022-2032. A number of challenges related to implementation of inclusion in Ukrainian higher education institutions dealing with operation of local and national authorities have been identified, as well as the absence of cooperation between authorities, higher education institutions, civic organizations, which hampers facilitation of inclusion in higher education; lack of educational infrastructure and methodical support for inclusive education in higher education institutions; inadequate level of academic staff competences in the field of inclusive education; absence of psychological support for students with special educational needs, other students and teachers. The National Strategy for Inclusive Education Development for 2023 – 2030 should become the comprehensive strategic document outlining the directions for overcoming the identified challenges. The above document identifies strategic and operational goals of inclusive education development, effectiveness indicators and practical assignments. The article defines peculiarities of higher education inclusion implementation for each operational goal.
Distance Learning: Issues and Ways to Overcome Them
Authors: Buyanova Galina , Udalova Olena
Published: December 2023

This paper explores the concept of "distance learning" and theoretical and practical approaches to studying the problems that arise for academic and educational professionals, as well as higher education students, when implementing distance learning technologies in the educational process of higher education institutions. Based on the results of our research, the advantages and problems of distance learning that affect the success of education in higher education institutions are justified and summarized, including technical, psycho-pedagogical, organizational, managerial, and others. The combination of this type of learning with traditional methods allows time for obtaining, exchanging, and processing acquired educational information and completing tasks. It also provides opportunities for better communication, socialization, collaborative work between teachers and higher education students, and receiving assistance when needed.

Promising directions for improving distance learning have been identified: ensuring reliable internet connectivity for all participants in the educational process, creating accessible basic content for educators with the use of quality scientific and methodological support, utilizing modern information technologies, effective teaching methods, and electronic resources that consider the specifics of the distance format, and enhancing the professional development of academic and educational professionals.
Implementation of Ukraine's State Policy in Innovative Practices of Educational Institutions in the Context of Digital Transformation
Authors: Zavalevskyi Yury , Kyrilenko Svitlana , Kijan Olga , Bessarab Nataliya
Published: December 2023

In the article, the directions and strategic tasks of the state policy in the implementation of innovative practices of educational institutions, the direction of the ways of modernization of modern education in view of the integration of Ukraine into the European educational space are important; the views of scientists regarding the reform of the educational sphere were analyzed, especially the issues of digital transformation in education; new directions of program actions of the state, an effective management system for the innovative development of education in Ukraine in modern conditions, taking into account the European experience.

The requirements for scientific and theoretical substantiation and the development of a practical model for the modernization of comprehensive general secondary education and the improvement of the mechanism of regulation of modern innovative state practices, digitalization of new, new processes in educational institutions, and the regulatory tools of the state influence on this process have been determined.

Outlined specific tasks for the development of the educational process in educational institutions in the context of education reform in Ukraine, ensuring the functioning of the education system in the face of societal changes to implement state educational policies, innovative practices, scientific research, and methodological work.

Digitization based on the progressive development of network access technologies; semiconductor technologies; software and its cross-use, becomes an important condition in the field of education, and service models of interaction with users become the leading methods of communication.

Innovative educational projects are described, which highlight the general characteristics of innovations in education, the problems of their accounting and support; based on the analysis of the current state of implementation and dissemination of innovations in educational institutions within the limits of new means and directions of work, which cover all educational and methodological, educational activities of the school and lead to positive changes; modern approaches to the introduction of innovations into the system of general secondary education in Ukraine are formulated.
Bactericide polymers obtained from nitrofuran and chitosan derivatives
Authors: Prisacari Viorel , Buga Diana , Rusnac Roman , Caisim Liliana , Stefan Robu
Published: December 2023

Background: In this study, the synthesis and characterization of chitosan polymeric materials grafted with nitrofuran derivatives – furaceline and isofural in terms of antibacterial properties and prolongation of their action were performed. Material and methods: Synthesis of chitosan analog polymers with maleic anhydride was performed, followed by grafting of nitrofuran derivatives using ethyl chloroformate. The chemical composition of the obtained polymers was confirmed by FT-IR spectroscopy. Antibacterial study has been performed on a wide range of Gram-positive and Gram-negative microorganisms. Results: Chitosan derivatives with a content of 30 mol% of maleic anhydride were obtained. To the analogous polymer ”chitosan maleinized” the medicinal products isofural or furaciline with the help of the ethyl chloroformate were functionalized. By comparative analysis of the IR spectra of the final products with the IR spectra of maleinized chitosan and furacilin or isofuran was demonstrated the individual structure of the polymeric preparations “maleinized chitosan grafted with furacilin“ / “maleinized chitosan grafted with isofural”. The antibacterial substances, isofural and furaciline, among nitrofurans, being grafted with chitosan maleinized, keep their bactericidal activity in the limits of 75-300 μg/mL. The polymeric materials from chitosan maleate grafted with isofural or furacillin in a ratio of 70:30 have a prolonged antibacterial action (observation period 72 hours). Conclusions: It has been found that isofural and furacilin, among nitrofurans, being grafted on chitosan polymeric material, retain their bactericidal activity and possess prolonged antibacterial action.
From non-specific low back pain to chronic primary musculoskeletal low back pain: the evolving concept
Authors: Plesca Svetlana , Grosu Oxana , Sangheli Marina
Published: December 2023

Background: Low back pain (LBP) for many years is considered one of the most common conditions causing work absenteeism and long-term disability, with important implications for public health systems and economies. Pain generators of LBP are various, being distinguished specific and non-specific causative mechanisms. The term “non-specific” LBP remains ambiguous as potential sources of pain are supposed to be muscles or joints, but supplementary investigations do not correlate enough to explain the pain intensity and disability. The nociceptive and/or neuropathic mechanisms characteristic for acute pain tend to be influenced by central sensitization while pain chronification occurs, leading to new descriptor as nociplastic pain. Chronic low back pain, considered mostly non-specific, was mechanistically referred to primary musculoskeletal low back pain, the concept introduced in the new ICD-11 classification. The process of acceptance by the scientific medical community raised debates and discussions. The aim of the study was to analyze the evolving concept of non-specific low back pain to chronic primary musculoskeletal low back pain. A narrative literature review was carried out. Conclusions: The term non-specific low back pain is used when the pain generators have not been accurately determined or cannot fully explain the existing symptomatology. Chronic primary musculoskeletal low back pain is better explained by central sensitization mechanisms and altered nociception, named nociplastic pain. Because of raised ambiguities regarding this concept further studies are expected to shed light on the problem.
The writer and the power: Strategies of identity construction in the volume of documentary prose "Me and the world" by Alexei Marinat
Authors: Sorocean Inga
Published: December 2023

The author proposes to approach the identity of the character in the volume Me and the world by Alexei Marinat from the perspective of the construction and reconstruction of the self in relation to the totalitarian Power by bringing into discussion a potential crisis generated by the conflict between the identity imposed by the political Power and one’s own values. The relationship between the diary character, implicitly the one from the documentary prose fragments ‒ narratives that identify with A. Marinat, articulating the trajectory of the writer’s human and literary destiny, and totalitarian Power, the reactions of the budding writer to the identity project imposed by the system ‒ will be analysed to underline the consequences of political pressure on the character’s moral profile. Thus, the study offers a broad perspective on the meaning of Power, seen on the one hand as "a diabolical force" and on the other hand as a "necessary evil" that involuntarily strengthens the identity of the individual, representing a case of resistance to the politics in which the power undoubtedly belongs to the writer A. Marinat.
Anatol Moraru: creative portrait
Authors: Rotari Dorina
Published: December 2023

This article explores the multifaceted activity of the writer, teacher, publicist and literary critic Anatol Moraru. Holder of the "Alecu Russo" State University in Bălți, member of the Union of Writers from the Republic of Moldova and from Romania, Anatol Moraru stands out for his extensive literary, scientific and didactic activity, publishing works on the creation of Ion Druță and Dumitru Matcovschi, a volume of studies, articles, chronicles, as well as more than 30 scientific articles in collective volumes and anthologies. In contemporary Romanian literature, the writer imposes himself through an uninhibited prose about the tragicomic condition of the Bessarabian, through an ingenious, provocative and persuasive writing, fueled by bookish and real experiences, which shows an exuberance of expression and "a pleasure of speaking".
Mircea V. Ciobanu’s Critical Review: interpretative rigour and discursive lightness
Authors: Abramciuc Maria
Published: December 2023

Resulting from a rhythmic activity of review and interpretation of literary creations from the present-day Bessarabian space and from other regions, Mircea V. Ciobanu is a model of mediation between the literary work and the reader. The studies, articles and literary reviews included in the volumes signed during the years 2008-2021 reveal his commitment to the perception and diagnosis of relatively recent publications in Romanian literature from the left bank of the Prut, the authentic reflective perspectives, as well as the discursive lightness, a distinctive feature of his writing. Spectacular theoretical delineations, selected examples from world literature of all epochs, the frontal assessments and stark demonstrations, the stylistic chromaticism of the phrase ‒ all of these showcase Mircea V. Ciobanu’s profile as a professional in the domain.
Superstitions and representations of the bridge in the novel "Devil’s Bridge" by Radu Paraschivescu
Authors: Girlea Olesea
Published: December 2023

In the communication I address the specifics of the sumptuous constructions and the superstitions related to their greatness. I refer to the novel "Podul diavolului" by Radu Paraschivescu (2022), which brings to the fore issues related to the pact with the devil and the curse of the bridge that ensures its durability and longevity. At the same time I capture the symbolism of the bridge from the idea of the place of passage and trial to that of the initiatory journey.
Poses of laughter and its artistic valences in the novel Moromeții by Marin Preda
Authors: Ivanov Nadejda
Published: December 2023

The present communication analyzes the most representative postures of laughter, the humorous, ironic expressions uttered by the literary characters from the novel Moromeții (vol. I) by Marin Preda, in various family contexts or existential conflicts. The smile and specific way of laughing of each character outlines his moral, psychological portrait, highlighting, at the same time, the importance and semantic role of such an affective reaction.