bluuebunny/crossref_metadata_2025 huggingface dataset:
Automated Determination of Left Ventricular Function Using Electrocardiogram Data in Patients on Maintenance Hemodialysis
Authors: Vaid Akhil , Jiang Joy J. , Sawant Ashwin , Singh Karandeep , Kovatch Patricia , Charney Alexander W. , Charytan David M. , Divers Jasmin , Glicksberg Benjamin S. , Chan Lili , Nadkarni Girish N.
Published: June 2022

Background and objectives

Left ventricular ejection fraction is disrupted in patients on maintenance hemodialysis and can be estimated using deep learning models on electrocardiograms. Smaller sample sizes within this population may be mitigated using transfer learning.

Design, setting, participants, & measurements

We identified patients on hemodialysis with transthoracic echocardiograms within 7 days of electrocardiogram using diagnostic/procedure codes. We developed four models: (1) trained from scratch in patients on hemodialysis, (2) pretrained on a publicly available set of natural images (ImageNet), (3) pretrained on all patients not on hemodialysis, and (4) pretrained on patients not on hemodialysis and fine-tuned on patients on hemodialysis. We assessed the ability of the models to classify left ventricular ejection fraction into clinically relevant categories of ≤40%, 41% to ≤50%, and >50%. We compared performance by area under the receiver operating characteristic curve.

Results

We extracted 705,075 electrocardiogram:echocardiogram pairs for 158,840 patients not on hemodialysis used for development of models 3 and 4 and n=18,626 electrocardiogram:echocardiogram pairs for 2168 patients on hemodialysis for models 1, 2, and 4. The transfer learning model achieved area under the receiver operating characteristic curves of 0.86, 0.63, and 0.83 in predicting left ventricular ejection fraction categories of ≤40% (n=461), 41%–50% (n=398), and >50% (n=1309), respectively. For the same tasks, model 1 achieved area under the receiver operating characteristic curves of 0.74, 0.55, and 0.71, respectively; model 2 achieved area under the receiver operating characteristic curves of 0.71, 0.55, and 0.69, respectively, and model 3 achieved area under the receiver operating characteristic curves of 0.80, 0.51, and 0.77, respectively. We found that predictions of left ventricular ejection fraction by the transfer learning model were associated with mortality in a Cox regression with an adjusted hazard ratio of 1.29 (95% confidence interval, 1.04 to 1.59).

Conclusion

A deep learning model can determine left ventricular ejection fraction for patients on hemodialysis following pretraining on electrocardiograms of patients not on hemodialysis. Predictions of low ejection fraction from this model were associated with mortality over a 5-year follow-up period.

Podcast

This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2022_06_06_CJN16481221.mp3
The Spirituala Poems of Mahanand Sharma
Authors: Singh Shaleen Kumar , Sharma Alka
Published: June 2022

Indian English Poetry is rich in Indian themes and symbols. Although the poets have drawn poetic elements from the Indian soil, theme of spirituality is still left untouched by the IWE. Mahanand Sharma’s poetry is the poetry of spiritual taste. As a poet of Modern Indian English sensibility, he has captured the diverse themes of Indian spirituality and mythology. His collection titled A Rudraksha Rosary and Other Poems is an interesting story of Lord Shiva written in Miltonic blank verse. However, the poet has employed the eighteenth-century diction, he has remained novel in his tackling of themes and myths of Lord Shiva. In a comprehensive manner, he uncovers the valour and exploits of Lord Shiva and provides the spiritual light to the people groping in dark of materialism. This paper is a modest attempt to unravel the spiritual strains in the poetry of Mahanand Sharma.
THE RIGHT TRIANGLE THEOREM IN COMPARISON OF RELAVISTIC ENERGY
Authors:   Universitas Jember, Supriadi Bambang , Istighfarini Elma Tri ,   Universitas Jember, Amelia Fitri ,   Universitas Jember, Mardhiana Hana ,   Universitas Jember, Sari Putpita ,   Universitas Jember
Published: June 2022

Physics is a branch of scientific knowledge that requires understanding other disciplines, such as mathematical concepts. As for the development of increasingly advanced technology, it affects the world of education such as the implementation of CBT (Computer Based Test). Based on this, of course, innovation is needed to solve physics problems in a short and easy time. One example of material taught in physics that can be done in an easier way is material on special relativity. The solution to the problem of Einstein's special relativity, especially the comparison of relativistic energy, can use a right triangle by fulfilling the Pythagorean equation. This study describes the analysis of the right triangle theorem with the relativistic energy comparison equation.
Sentimental Analysis on Live Twitter Data
Authors: Ranpis Tanai , Mavkar Divya , Sarda Sharang , Pawar Rushikesh
Published: June 2022

Abstract: The entire world is transforming quickly under the present innovations. The Internet has become a basic requirement for everybody with the Web being utilized in every field. With the rapid increase in social network applications, people are using these platforms to voice them their opinions with regard to daily issues. Gathering and analyzing peoples’ reactions toward buying a product, public services, and so on are vital. Sentiment analysis (or opinion mining) is a common dialogue preparing task that aims to discover the sentiments behind opinions in texts on varying subjects. In recent years, researchers in the field of sentiment analysis have been concerned with analyzing opinions on different topics such as movies, commercial products, and daily societal issues. Twitter is an enormously popular microblog on which clients may voice their opinions. Opinion investigation of Twitter data is a field that has been given much attention over the last decade and involves dissecting “tweets” (comments) and the content of these expressions. As such, this paper explores the various sentiment analysis applied to Twitter data and their outcomes.
Online Voting System
Authors: Barkale Atharv , Jadhav Aditya , (Kumbhar) A. S. Salavi
Published: June 2022

Abstract: We are developing an on-line voting system by taking advantage ofthe centralized database with a web interface. The main concept of this project is to build a website, which should be able to allow peopleto cast their vote by online. Time saving, working load reduced, information available at timeand it provide security for the data. The election commission will maintain this websit
Assessing the vulnerabilities in databases and securing NoSQL Databases like MongoDB and Cassandra databases
Authors: M Ms. Sumi , C S Mr. Sreeraj
Published: June 2022

Abstract: On account of the rising amounts and the stand-out kinds of realities that need to be saved inside the Databases, offices, and organizations are quickly taking on NoSQL data sets to contend. Those data sets have been not planned with security as fundamentally important. NoSQL open-supply programming changed into In the primary high level to deal with unstructured measurements for the intention of business insight and Selection help. Throughout the long term, insurance highlights have been added to those data sets, but they are not quite as tough as they should be, and there's a degree for advancement as the complexity of the programmers has been expanding. In addition, the mapping less design of those data sets makes it more noteworthy intense to place into impact regular RDBMS like security capacities in those data sets. Famous NoSQL information bases are MongoDB and Apache Cassandra. Despite the fact that there are loads of examinations related to well-being weaknesses and tips to upgrade the security of NoSQL Databases, this exploration focuses especially on MongoDB and Cassandra data sets. This gander at goals to find and investigate all of the assurance weaknesses that MongoDB and Cassandra Databases have which can be specific to them and give you a stage through the advance manual that can help organizations to comfortable their records put away in these data sets. That is extremely urgent because of the reality the plan and weaknesses of each NoSQL data set are not quite the same as one another and thus require security hints which can be intended for them. Keywords: vulnerability, Database, Securing, NoSQL, MongoDB, Cassandra
Condition Monitoring of Power Transformer By Using Fuzzy Logic
Authors: Tarare Suraj , Dhadekar Rohit , Kadam Krishna , Meshram Ankit , Golha Shubham , Raut Yogendra
Published: June 2022

Abstract: This work did focuses on problem identification due to faults in power transformers during operation by using dissolved gas analysis such as key gas, IEC ratio, Duval triangle techniques, and fuzzy logic approaches. Then, the condition of the power transformer is evaluated in terms of the percentage of failure index and internal fault determination. Fuzzy logic with the key gas approach was used to calculate the failure index and identify problems inside the power transformer.
Human Activity Recognition With Smartphone
Authors: Bhandar Shubham i , Biradar Aishwarya , Kshirsagar Aditi , Biradar Preeti , Kekan Jayshri
Published: June 2022

Abstract: Human Activity Recognition (HAR) is designed to classify activities performed by human beings using responsive sensors inbuilt in smartphones that are affected from their movements. HAR is one of the most important technology that has wide applications in medical research, human survey system and security system, fitness etc. In this project we are predicting what a person is doing based on their trace movement using smartphone sensor. Movements include normal indoor human physical activities such as standing, sitting, walking, running, walking upstairs, walking downstairs. Smartphones has various built-in sensors like accelerometer and gyroscope. This system captures the raw sensor data from mobile sensors as input, process it and predicts a human activity using machine learning techniques. We analyze the performance of two classification algorithms that is Decision Tree (DT), Convolutional Neural Network (CNN). In this project, we build a robust activity detection system based on smartphones. Experiment results show that the classification rate of algorithms reaches 98%. In this project we propose a platform for identifying real-time human activity. Keywords: Machine Learning, Deep Learning, Activity Recognition, Smartphone, Accelerometer, Gyroscope, CNN, DT.
Custom Object Detection and Analysis in Real Time: YOLOv4
Authors: Kumar Aayush , Kumar Amit , Chandra Avanish , Adak Indira
Published: June 2022

Abstract: Object recognition is one of the most basic and complex problems in computer vision, which seeks to locate object instances from the enormous categories of already defined and readily available natural images. The object detection method aims to recognize all the objects or entities in the given picture and determine the categories and position information to achieve machine vision understanding. Several tactics have been put forward to solve this problem, which is more or less inspired by the principles based on Open Source Computer Vision Library (OpenCV) and Deep Learning. Some are relatively good, while others fail to detect objects with random geometric transformations. This paper proposes demonstrating the " HAWKEYE " application, a small initiative to build an application working on the principle of EEE i.e. (Explore→Experience→Evolve). Keywords: Convolution Neural Network, Object detection, Image classification, Deep learning, Open CV, Yolov4.
Electronic Attendance Recorder and Confirmation System Using Facial Identification Modules in Python
Authors: Nandy Zenith , Sengupta Indrani , Mondal Shuvashish , Sahil Sk , Pal Soumen
Published: June 2022

Abstract: The following paper demonstrates about a project that is basically an automated pre-programmed attendance management system. The system implements various image processing libraries/modules of the Python programming language. The main dependency is the face_recognition library, contributed by Adam Geitgey. The other dependencies used here are openCV, xlsxwriter, dlib, datetime, numpy and smtp service. This system analyzes camera roll frame by frame, looks for the known faces if found any, records the corresponding name and the time of detection. An email is sent to that person confirming the attendance with a mail id to report any unusual activities. After the system closes, the attendance details (name and first detection time) is saved in an excel sheet. Keywords: Attendance system, face recognition, facial identification modules, python, opencv, email service using python
The fire safety of infrastructure facilities for hydrogen-powered vehicles
Authors: Gordienko D. M. , Shebeko Yu. N.
Published: June 2022

Introduction. The article offers an analytical review of domestic and foreign publications on the fire safety of hydrogen refueling stations and garages for hydrogen-powered vehicles.

General characteristics of the fire hazard of infrastructure facilities for hydrogen-powered vehicles. The authors offer the general characteristic of a specific fire hazard from facilities using compressed and liquid hydrogen.

Hydrogen refueling stations. Refueling stations using compressed and liquid hydrogen were considered in the article. It was found that compressors are the most hazardous items installed at refueling stations; therefore, the value of potential risks, arising in the area of a refueling station, exceeds 10–4 year–1. Experiments, simulating accidents at hydrogen refueling stations, are described. According to the authors, the minimal distance between the compressor and facilities located outside the station area should exceed 50 m.

Garages for hydrogen-powered vehicles. Features of the fire safety of garages for hydrogen-powered vehicles were analyzed. The authors have found that the overpressure inside a small garage (an individual garage) can reach 55 kPa in case of a jet flame caused by the release of hydrogen through the safety valves of fuel tanks. The overpressure of a hydrogen jet can reach 10 kPa in case of the unignited release of hydrogen. High pressure values that accompany the jet formation are triggered by the high normal burning velocity of hydrogen that boosts the velocity of heat release in the flame front, exceeding the same value for flares of hydrocarbon gases. Therefore, requirements, applicable to storage premises designated for vehicles powered by hydrocarbon fuel, may be erroneously extended to garages for hydrogen-powered vehicles (pursuant to NFPA 2).

Conclusions. The results of this analysis can be contributed to regulatory documents to be developed in the area of fire safety of infrastructure facilities for hydrogen-powered vehicles.
Current requirements to designing fire protection systems for educational establishments
Authors: Pekhotikov A. V. , Poletaev A. N. , Gomozov A. V. , Usolkin S. V.
Published: June 2022

Introduction. It is necessary to update requirements for designing fire protection systems for these facilities in terms of the safe evacuation and rescue of children and personnel, increase the efficiency of fire emergency response units conducting rescue operations, as well as optimize space planning and structural solutions to ensure a high level of fire safety inside buildings of preschool and general education organizations.

Goals and objectives. The purpose of the article is to validate the updated requirements for designing fire protection systems for buildings of preschool and general education organizations in compliance with the Federal Law of the Russian Federation dated July 22, 2008 № 123-FZ «Technical regulations governing fire safety requirements» (hereinafter – «№Law 123-FZ»).

Methods. An analytical method is used to formulate and substantiate the requirements for designing fire protection systems for educational establishments within the framework of the integrated application of Law 123-FZ and with regard for current trends in architecture and structural design of similar buildings, as well as fire risk calculations.

Results. The results of the work are contributed to the amended sets of effective fire safety rules, such as SP 1.13130.2020 «Fire protection systems. Evacuation routes and exits», SP 2.13130.2020 «Fire protection systems. The fire resistance of protected facilities», SP 4.13130.2013 «Fire protection systems. Restricting fire spread throughout protected facilities. Requirements for space planning and structural solutions» (Amendment 1), etc., as well as SP 251.1325800.2016 «Buildings of general education organizations. Design rules» (Amendment 3).

Conclusion. The research findings were employed to substantiate the current requirements for designing fire protection systems for educational establishments to improve the safety of children in the process of evacuation and rescue, if these buildings have premises featuring various classes of functional fire hazard, fire resistance limits and fire hazard classes of building structures, building materials and engineering installations.
Augustinas Voldemaras and Soviet-Lithuanian Relations in 1926-1929
Authors: Rupasov Aleksandr I.
Published: June 2022

The article analyzes the nuances of the changes in Soviet-Lithuanian relations after the coup d'etat staged in December 1926. The coming to power of the leaders of the Lithuanian Nationalist and Republican Union A. Smetona and A. Voldemaras initially contributed to the situation of uncertainty in bilateral relations. Moscow was extremely concerned about Voldemaras' desire to exacerbate the Polish-Soviet contradictions in order to solve the Vilnius problem in Polish-Lithuanian relations. The Soviet diplomats feared that Voldemaras could provoke an armed conflict with Poland and that the Soviet Union would inevitably be involved in the conflict. On the other hand, Soviet diplomacy was interested in maintaining both the independence of Lithuania and the maintenance of some tension between Poland and Lithuania, as this situation created obstacles to Poland’s spread of influence throughout the Baltic East. By the late 1920s, it became apparent to Moscow that dissatisfaction with Voldemaras’ policy in Lithuania had reached its climax and that Voldemaras was to be forced out of Lithuanian political life in the near future. As a result, a few months before Voldemaras’ resignation, the political leadership of the USSR categorically opposed contacts with him by the leadership of the People’s Commissariat for Foreign Affairs.
Review of Lamazhaa, Ch.K., and Suvandii, N.D., eds. Dagylga: tuvinskie obriady osviashcheniia v XXI veke [Dagylga: Tuvan rites of consecration in the 21st century]. Kyzyl, 2021. 188 p.
Authors: Popkov Yuri V.
Published: June 2022

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Los hábitos analógicos del periodismo en plena Revolución Digital
Authors: Abreu Colombri José Antonio
Published: June 2022

La obra reseñada es un ensayo elaborado dentro de un marco narrativo muy original, con el diálogo de dos periodistas de reconocido prestigio. La estructura de este proyecto editorial se compone de un apartado introductorio, cinco capítulos y una nota aclaratoria sobre la colección y el objetivo de la obra. Los títulos y las temáticas de los cinco capítulos guardan relación con el proceso de composición de la información periodística: “Who” (primero), “What” (segundo), “When” (tercero), “Where” (cuarto) y “Why” (quinto). El libro afirma reiteradamente que el periodismo de calidad no está lo suficientemente valorado por los consumidores y por los gestores de las empresas comunicativas.
20 minutos, referente de la prensa gratuita en España y su aportación al periodismo online: de organizador de noticias a los géneros dialógicos
Authors: Argiñano Jose-Luis , Goikoetxea-Bilbao Udane
Published: June 2022

Con su eclosión a principios de siglo, la prensa gratuita convulsionó el panorama mediáticoy obligó a la prensa de pago a cambios formales y editoriales. A partir de siete entrevistas enprofundidad a los responsables de 20 Minutos, este trabajo describe la organización y el contenidode este diario gratuito, el primero en fusionar en España las redacciones de papel y web. Estafusión supuso cambios de organización en la redacción y alteraciones formales en el contenido,antes incluso de la llegada de las redes sociales. 20 minutos, más que como un medio clásico deinformación, se entiende mejor como un organizador de noticias. Su variedad temática, consecciones transversales, se pueden contemplar hoy en día en los home de los diarios nativosdigitales. La interactividad se incrementa con la gestación de los géneros dialógicos, comochats, encuestas entre los lectores o entrevista online en directo. Los resultados también muestranla incidencia en el producto de la ausencia de una línea editorial politizada o que la propietaria de laempresa sea un importante grupo de comunicación de origen noruego. La posibilidad, porprimera vez, de conocer al instante el tráfico de cada noticia en la página web condicionanel periódico de papel del día siguiente. Se puede concluir que el carácter pionero de 20 Minutospropició cambios formales y estructurales en el quehacer periodístico que se trasladarona la prensa online y que perduran en el tiempo, como el poder del click, el engagement o una agendasetting más extensa, y espacios más dialógicos que suscitan el interés del lector.
Lineamientos para el uso de la hipermedialidad, multimedialidad e interactividad en el ejercicio periodístico digital comunitario para redes sociales (Facebook). Caso de análisis de la Red de Reporteros Comunitarios de Colombia (RRC)
Authors: Ladino Marín Paola Consuelo , Prada Penagos Rodolfo , Adán Diaz Oscar Eduardo
Published: June 2022

Este artículo busca proponer lineamientos estratégicos para el uso de la hipermedialidad, multimedialidade interactividad en el periodismo comunitario mediado por redes sociales, específicamenteFacebook, tomando como referencia el caso de la Red de Reporteros Comunitarios de Colombia(RRC). Metodológicamente se realizaron tres fases que vincularon: análisis de los recursos digitalesdesde la práctica periodística de la RRC, examinando los baremos de medición de Fondevila (2014)para categorizar los contenidos de la plataforma; un diagnóstico de las herramientas utilizadasen las publicaciones; y una propuesta estratégica que mejore el uso de RRSS en medios comunitarios.Como hallazgos se destaca que los medios comunitarios deben enriquecer e integrar diversosrecursos y géneros del lenguaje periodístico para potencializar sus contenidos. Así como establecerun diálogo permanente con la comunidad, ampliar el uso de enlaces para profundizar contenidos, validarlas normas de redacción en la red, como apoyarse de contenidos infográficos que den contexto,como aspectos asociados a la generación de tráfico, la segmentación de audiencias, el enriquecimientodel diálogo social y la independencia de los ámbitos de poder del Estado.

Para la Unesco la función de este tipo de medios asegura la participación ciudadana, refuerza la libertad de expresión, defiende los Derechos Humanos de la comunidad y promueve el desarrollo social. En esta dimensión, se reconoce que las plataformas sociales han tomado fuerza en la democratización de la información, la movilización de contenidos críticos que dan voz a diversos segmentos de la población y fortalecen los vínculos entre el medio y la comunidad.

Como hallazgos se destaca que los medios comunitarios deben enriquecer e integrar diversos recursos y géneros del lenguaje periodístico para potencializar sus contenidos. Así como establecer un diálogo permanente con la comunidad, ampliar el uso de enlaces para profundizar contenidos, validar las normas de redacción en la red, como apoyarse de contenidos infográficos que den contexto, como aspectos asociados a la generación de tráfico, la segmentación de audiencias, el enriquecimiento del diálogo social y la independencia de los ámbitos de poder del Estado.
From Parochialism to Cosmopolitanism in the American Audiovisual Supply? Netflix’s New Releases of Television Fiction in the United States and their Geographical Diversity
Authors: Lozano Jose Carlos
Published: June 2022

The supply of films and TV series in the United States has been historically dominated by national programming produced by its powerful media conglomerates, significantly limiting the diversity and plurality of choices for their American viewers. Netflix and other video-on-demandplatforms are changing this situation, significantly increasing the availability in the United States of fiction produced in different regions of the world, potentially exposing their subscribers to new narrative styles, scenarios, ethnicities, nationalities, languages, and cultural features. This study, based on the methodology of content analysis, analyzes the geographical origin and production type of new Netflix scripted television releases in the United States from January 2017 to June 2018 and discusses their potential relevance in broadening the degree of geographical diversity among American subscribers to the platform. The paper concludes that while Netflix USA substantially increased the supply of foreign television series in its catalog during that period, a sizeable part of the imports came from countries with high degrees of “cultural proximity” with the United States. The article concludes by discussing the possible “Americanization” of foreign audiovisual productions, formats, and genres bought or produced by Netflix.
MEMBANGUN KOMPETENSI ALUMNI DALAM MENGEMBANGKAN SOAL SOSIOLOGI BERBASIS LITERASI DAN NUMERASI
Authors: Purwasih Joan Hesti Gita , Pratiwi Seli Septiana , Apriadi Deny Wahyu
Published: June 2022

In generally, most of the training and mentoring of teachers is temporary. More intense and sustainable efforts are needed so that the teacher's abilities can continue to be developed. These efforts can be carried out by involving alumni who are already working as teachers. This continuous organization and quality assurance is also the responsibility of the Study Program in improving the quality of graduates and users. In addition, this is a way out that benefits various parties in improving the quality of human resources. The method used is a participatory method with alumni who are participants in the activity. Mentoring is carried out individually and in groups through mentoring techniques which are divided into concept delivery and preparation of literacy and numeracy-based assessments. As a result, alumni who work as teachers have proven their ability to develop an assessment prototype in the form of multiple choice questions based on literacy and numeracy. Mentoring pays attention to the structure of the content with a duration of 32 hours of lessons. The assistance provided also proves the ability of collaboration between study programs and alumni to ensure sustainable quality of human resources.
PERAN PROGRAM MERDEKA BELAJAR KAMPUS MERDEKA DALAM MENINGKATKAN KEMANDIRIAN DESA
Authors: Yanuarsari Revita , Asmadi Iwan , Muchtar Hendi Suhendraya , Sulastini Rita
Published: June 2022

Ilmu pengetahuan dan teknologi yang berkembang sangat pesat telah membawa banyak perubahan dalam berbagai aspek kehidupan. Pendidikan dewasa ini harus dapat beradaptasi dengan perubahan yang ada termasuk diantaranya perubahan kebiasaan karena keadaan dunia yang sedang mengalami pandemi covid 19. Merdeka Belajar dan Kampus Merdeka merupakan salah satu kebijakan Menteri Pendidikan dan Kebudayaan Nadiem Anwar Makarim untuk merespon perubahan tersebut. Salah satu program yang terdapat di program MBKM adalah proyek di desa. Penelitian ini menggunakan metode penelitian kualitatif dengan metode deskriptif analisis berdasarkan kajian literatur atau riset kepustakaan. Hasil penelitian mengatakan bahwa proyek di desa menjadi salah satu sarana penguatan karakter mahasiswa. Sebagai calon pemimpin masa depan, mahasiswa ditantang untuk keluar dari zona nyamannya dan berlatih menghadirkan solusi dari problem yang ditemuinya di desa. Diharapkan dengan adanya program MBKM ini juga dapat membantu mewujudkan desa-desa mandiri di Indonesia.
Didáctica para el aprendizaje de algoritmos
Authors: Dueñas Meza José María , Valdés Benjumea Jaime José , Rodríguez Niño María Consuelo
Published: June 2022

El libro “Didáctica para el aprendizaje de algoritmos” surge como una herramienta metodológica que apoya el proceso de enseñanza aprendizaje de los estudiantes para el dominio en la presentación y resolución de problemas, en efecto dar soluciones informáticas a través de los algoritmos; en tal sentido destacar que el estudio del mismo requiere de mucha disciplina y dedicación. Al realizar este libro se parte del interés de la metodología como se enseña una materia que al principio muchos estudiantes la ven compleja; pero que necesita mucha disciplina y dedicación para aprender a dominar la forma como se presentan y resuelven los problemas para dar soluciones informáticas a través de los algoritmos. En este mismo contexto, a través del tiempo muchos estudiantes piensan erradamente que la Ingeniería de Sistemas o programas afines es solo manejar el paquete ofimático de Microsoft Office o navegar en la Internet, sin conocer a fondo las diferentes perspectivas de lo que realmente son las carreras de la rama de la informática o computación; teniendo en cuenta que en realidad por medio de los algoritmos se forma una base para iniciar la creación de los programas o paquetes ofimáticos y otros de acuerdo con una necesidad. Atendiendo a todas estas consideraciones, el libro está escrito para aquellas personas que vean la necesidad de aprender a realizar programas desde cero, para así desarrollar la forma de analizar los problemas y posteriormente comprobarlos mediante la prueba de escritorio, dándole valores arbitrarios a las variables para verificar si el resultado dado cumple con el enunciado propuesto de cada ejercicio.
Alternativas de producción agroecológica urbana periurbana y su contribución en la seguridad alimentaria de Colombia
Authors: Carranza Gutiérrez Carlos Edwin , Vinasco Guzmán Martha Cecilia , Mosquera Mena Ramón Antonio , Montenegro Gómez Sandra Patricia , Serrato Velosa Yetfersson Arley , Prada Millán Yolvi , Sepúlveda Casadiego Yulian Adalberto
Published: June 2022

La agricultura urbana y periurbana ha mostrado resultados positivos en la mitigación de la inseguridad alimentaria en los espacios urbanos, no obstante, es un proceso que requiere apoyo económico y técnico con la finalidad de optimizar resultados, y que los mismos sean apropiados por la población. En Colombia actualmente no existen políticas gubernamentales para apoyar estos procesos, sin embargo, algunas iniciativas territoriales y particulares evidencian una gran oportunidad de fortalecimiento nutricional. Desde la perspectiva técnica, el presente libro brinda al lector una contextualización de experiencias relevantes y herramientas técnicas útiles para la implementación de huertas agroecológicas urbanas y periurbanas.
Las inteligencias múltiples y estilos de aprendizaje: didáctica para cursos medidos por tecnologías
Authors: Verney Latorre Clara Tatiana , Paredes Rosales Claudia Andrea , Vélez Pombo Mercedes Cecilia , Estupiñán Sánchez Emilse , Tolosa Rada Laura Gisella , Casas Segura Juan Carlos
Published: June 2022

Este libro presenta los resultados del trabajo de investigación desarrollado por cuatro docentes y un estudiante del programa de Psicología a partir de un interés colectivo de indagar sobre el perfil de la inteligencias múltiples y estilos de aprendizaje desde bases neuropsicológicas que favorezcan el aprendizaje de los estudiantes del programa, quienes pertenecen a tres momentos diferentes del proceso formativo (inicial - intermedio - final).
Decommission of a Heartmate 3 LVAD in a patient with left ventricular recovery
Authors: Schaffer S. Allan , Shannon Stephen
Published: June 2022

Background: Left ventricular assist devices have been a
significant development in the treatment of patients with advanced heart
failure supporting circulation as a bridge to transplant, recovery or
long-term destination therapy. When ventricular recovery occurs, there
are multiple described ways of proceeding. HM2 decommissions are well
described with varying degrees of explant operations, less so in HM3 due
to the novelty of the device. In certain situations, invasive surgery
can carry high risk and so a minimally invasive decommission, leaving
the LVAD essentially intact in situ can be considered. Case
report In this report, we describe the case of a 35-year-old male
diagnosed with an idiopathic dilated cardiomyopathy requiring an LVAD
with subsequent identification of cardiac recovery with the asymptomatic
thrombosis of the 2 HM3 device. Investigations
demonstrated absent flow through the pump whilst the patient-reported
NYHA I functional class symptoms. The Driveline was cut with the
remaining internal pump components decommissioned and left in situ. At 1
year the patient continues to do well with continued features of cardiac
recovery with an LVEF of over 40%. Conclusion LV recovery is
well recognized with typical management being LVAD explant surgeries
performed. Each case should be analyzed for risks and benefits to the
patient and future research showed be directed towards levels of
decommissioning surgery and management post-LVAD decommission patient
care.
A long-term overdose use of clonidine in a peritoneal dialysis patient: A case study
Authors: wu shujuan , chen xiaohai , miao chusheng , huang chunyan
Published: June 2022

Clonidine is an alpha-adrenergic receptors and used in the treatment of
hypertensive. We described a 22-year-old man with end-stage renal
disease and hypertension overdose use for 7 years in a peritoneal
dialysis patient do not cause severe toxicity except exhilarate.
Recurrent Sinopulmonary Infections and Poor Growth in a Child Homozygous for the CFTR 5T-TG12 Variant
Authors: Ebrahim Mohamed , Fox Eryn , Treyster Zoya
Published: June 2022

N/A-article is a clinical correspondence, thus does not include an
abstract
The identification of a novel frameshift insertion mutation in the EXT1 gene in a Chinese family with Hereditary Multiple Exostoses
Authors: Liu Wanlu , Shi Xinwei , Li Yuqi , Qiao Fuyuan , Wu Yuanyuan
Published: June 2022

A novel heterozygous mutation (c.325dup) was identified in EXT1 gene
from the proband and the affected family members; this mutation was
absent in all the unaffected family members. The identification of the
novel frameshift insertion mutation (c.325dup) expands the mutation
spectrum of HME, which provides new evidence for HME diagnosis.
The Path to Kina Convertibility: An Analysis of Papua New Guinea’s Foreign Exchange Market
Authors: Davies Martin H. , Schröder Marcel
Published: June 2022

This paper recommends an immediate and frontloaded exchange rate depreciation that can encourage an adjustment process to address the foreign exchange shortage in Papua New Guinea. Due to a shortage in foreign exchange (forex) since 2015, the central bank of Papua New Guinea rationed forex that led to a large backlog of orders and import compression. The study finds that the policy proposals discussed in the country are inadequate to restore currency convertibility, based on surveys of the forex market structure and analysis of recent market conditions. It recommends more exchange rate flexibility and forex allocation through competitive auctions over the medium term.
Application of wearable motion sensor in business English teaching
Authors: Lu Dan , Guo Fen
Published: June 2022

With the advancement of science and technology, portable motion sensors are becoming increasingly popular in life and have become a research point for improving life and learning, and are widely used in medical care and smart terminals. Based on the advantages of portable motion sensors, this paper focuses on its application in learning English business. Collects speech information through special motion sensors, analyzes the accuracy of students' reading through speech recognition, to help students better learn business English. Firstly, the wearable sensor is used to collect and preprocess the speech information of students' business English reading as the input of speech recognition. Secondly, the linear predictive cepstrum coefficient (LPCC) and Meier frequency cepstrum coefficient (MFCC) of students' business English reading speech are extracted, and the mixed parameters of LPCC and MFCC are taken as speech features. Finally, the correctness of reading speech is recognized by combining HMM and WNN. Through the simulation analysis of students' reading speech recognition, it is shown that the speech recognition based on wearable motion sensor is feasible and the recognition method has good performance. In addition, the feasibility of wearable motion sensors in business English teaching is verified by the establishment of an experimental classes, which can promote students' English learning better.
The research and implementation feasibility analysis of an intelligent robot for simulating navigational English dialogue under the background of artificial intelligence
Authors: Sun Wei
Published: June 2022

The rapid development of artificial intelligence and robots, the research and development of intelligent dialogue robots are very necessary for today's society. However, a robotic algorithm system that simulates navigational English conversation has not yet been developed. In order to find a suitable algorithm system for dialogue robots, this paper uses the test data set to test the analytical model of navigational English dialogue instructions. The experimental results show that the conditional random field (CRF) + domain dictionary + ambiguity resolution method has the highest segmentation effect. The calculated percentages of the analytical model are correct rate: 76.85%; recall rate: 80.36%; F-value: 88.46%. This paper implements a robot teaching and reproduction method based on simulated navigational English conversation and human-computer interaction under the background of artificial intelligence, and designs robot motion realization experiments and speech recognition experiments. The three-dimensional error after fine-tuning the voice is between 1.6798mm and 2.9968mm. This article constructs a simulation navigational English dialogue robot system. The FAQ component has up to 79.2%; others have a lower accuracy rate of only 59.03%.
Material Sustainability and Stock Return: Faith is Not Enough
Authors: Berchicci Luca , King Andrew A.
Published: June 2022

Yoon and Serafeim (2022) provide a review of the history of materiality, a brief discussion of selected research, and a discourse on measurement noise. They do not address the results of our research, our critique of their analysis, or our evidence that the main finding of Khan, Serafeim, and Yoon (2016) is a statistical artifact. In total, their response illustrates the danger of placing excessive faith in the findings from a single study.
1475-PUB: A Crucial Role of miR-223-3p in Endothelial Cell Injury with Diabetes Kidney Disease
Authors: TANG PING , JINGRONG ZHANG , ZHANG LIHUA
Published: June 2022

Diabetic kidney disease (DKD) is a leading cause of chronic and end-stage renal failure in the world. However, the underlying molecular mechanisms are various and not completely understood. In our previous study, miR-223-3p was identified as the most significantly decreased miRNAs and showed a disease-dependent expression in the plasma of DKD patients through microarray analysis, which was involved in biological processes, such as cell proliferation, differentiation, apoptosis and immune regulation. In the present study, we firstly used high glucose stimulation to establish human umbilical vein endothelial cells (HUVECs) injury in vitro DKD model and db/db mice in vivo DKD model, respectively.The preliminary qPCR study of related markers (VEGF, ET-1, vWF) and Western bolting analysis of GP130 and p-STAT3 indicated a successful HUVECs injury in vitro DKD model, and the significant increasingly expression of Vegfa, ET-1, vWF mRNA in db/db mice was observed. Most importantly, the expression of miR-223-3p was indeed significantly decreased in both high glucose stimulated HUVECs and db/db DKD mice. Of which, the target gene IL6ST also showed significantly high expression.

In conclusion, these results indicated that the expression change of miR-223-3p in vitro and vivo DKD model may related to endothelial cell injury with DKD progression.

Key words: Diabetic kidney disease (DKD) , miR-223-3p, HUVECs, db/db mice, IL6ST.

Disclosure

P.Tang: None. Z.Jingrong: None. L.Zhang: None.

Funding

National Natural Science Foundation of China (81960156) and Health Science and Technology Program of Yunnan Province[2019FE001 (-040) ]
1476-PUB: The Stimulation of High Glucose Can Downregulate Expression of miR-223-3p in HUVECs, Which May Undergo Endothelial–Myofibroblast Transition
Authors: ZHANG JINGRONG , TANG PING , ZHANG LIHUA , LI PAN
Published: June 2022

The early changes in renal glomeruli are crux for the development of glomerulosclerosis and nephron dropout in diabetic kidney disease (DKD) . Many studies have focused on the changes of the dysfunction of glomerular podocytes, the study of glomerular endothelial cells (GECs) are not completely understood. Human umbilical vein endothelial cells (HUVECs) are considered the classic model of endothelial cells (ECs) . The stimuliation of high glucose would induce the stress or injury of ECs. In our previous study, with the development of DKD, the the expression of miR-223-3p was significantly decreased in patients’ peripheral plasma, and bioinformatics methods predicted IL6ST as the target gene of miR-223-3p. We also proved that miR-223-3p target IL6ST and down-regulate its expression in 293T cells by using dual-luciferase reporter assay system.So the down-regulation of miR-223-3p could be viewed which induced by high glucose 24 hours in HUVECs and its target gene IL6ST significantly increased. After using high glucose stimulate the HUVECs, the proliferation and migration of HUVECs decreased, the qPCR study suggest that the expression of miR-223-3p significantly decreased, the endothelial jnjury factors (aVEGF, ET1) increased, and the fibrosis factor (αSMA, FN1) also increased. When up-regulate the expression of miR-223-3p in HUVECs by using miR-223-3p-mimic, the expression of IL6ST is down-regulated.The HUVECs may undergo endothelial-myofibroblast transition (EndoMT) after high glucose stimulation, and this process may be one of the cause of DKD glomerulosclerosis.

Disclosure

J.Zhang: None. P.Tang: None. L.Zhang: None. P.Li: None.

Funding

Financial Support: National Natural Science Foundation of China (81960156) , and Health Science and Technology Program of Yunnan Province[2019FE001 (-040) ]
1481-PUB: Gliclazide vs. Linagliptin on the Incidence of Hypoglycemia and Major Adverse Cardiovascular Events in Adults with Type 2 Diabetes: Narrative Synthesis of Systematic Literature Search
Authors: MOHAN VISWANATHAN , WANGNOO SUBHASH KUMAR , DAS SAMBIT , DHEDIYA RAJNISH , GAURAV KUMAR
Published: June 2022

Background: The CAROLINA, landmark cardiovascular outcome trial (CVOT) , has demonstrated cardiovascular safety of glimepiride against DPP-IV inhibitor linagliptin. Considering the absence of CVOT for Gliclazide, we decided to conduct a systematic review of the literature to assess the cardiovascular (CV) safety and hypoglycemia risk of gliclazide versus linagliptin in patients with T2DM.

Method: A systematic literature search of MEDLINE and Google Scholar was conducted to include all linagliptin ± metformin and gliclazide ± metformin trials from 20onwards that assessed the adverse events: hypoglycemia, myocardial infarction/ischemia, transient ischemic attack, cardiovascular death, and stroke. Two independent reviewers conducted a literature search and study selection according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Only randomized trials, considered the highest quality of evidence by the Oxford Center for Evidence-based Medicine, were included. We excluded placebo-controlled studies and studies comparing gliclazide or linagliptin with metformin.

Results: No trials compared gliclazide ± metformin with linagliptin ± metformin. Hence, it was impossible to directly compare their hypoglycemia and major adverse cardiovascular events (MACE) outcomes. Eight clinical trials were included in the narrative descriptive synthesis (gliclazide 5 and linagliptin 3) . Both drugs effectively achieved the desired glycaemic control and had low MACE and hypoglycemia risk in adults with T2DM. Studies comparing gliclazide with another DPP4 inhibitor, vildagliptin, did not report a significant difference in CV safety and/or hypoglycemia incidence.

Conclusion: Gliclazide can be used safely in patients with T2D in resource-limited settings as it has low MACE and hypoglycemia risk.

Disclosure

V.Mohan: None. S.Wangnoo: None. S.Das: n/a. R.Dhediya: None. K.Gaurav: Employee; Dr. Reddy’s Laboratories Ltd.
1482-PUB: Insulin Receptors in Vascular Smooth Muscle Cells Regulate Plaque Stability by Its actions on Glycolysis and Oxidative Phosphorylation
Authors: LI QIAN , FU JIALIN , PARK KYOUNGMIN , LI QIN , KING GEORGE L.
Published: June 2022

Vascular smooth muscle cells (VSMC) have prominent roles in the pathology of atherosclerotic plaque, where it forms intimal hyperplasia, maintains extracellular matrix (ECM) and interacts with lipoproteins to accelerate inflammation and formation of foam cells. Diabetes and insulin resistance exacerbate all of these histopathologies of atherosclerotic plaques. Further, diabetes increase the formation of unstable plaques that feature less VSMC and ECM, but more inflammatory cells and necrotic lesions, which, on rupture, cause thrombosis and acute myocardial infarction. We reported that insulin receptors (IR) are responsible for increasing arterial restenosis since mouse with IR deletion in the VSMC showed less proliferation, more apoptosis, and less arterial hyperplasia after intimal injury. Surprisingly, in mice with specific deletion of IR in VSMC (SMIRKO/ApoE-/-) , severity of atherosclerosis was increased and the plaques exhibited unstable pathologies of less VSMC and ECM, but greater levels of macrophages and necrosis than ApoE-/- mice. Analysis of glucose glycolysis (extracellular acidification rate, ECAR) and oxidative phosphorylation (oxygen consumption rate, OCR) , using Seahorse assay, showed dramatically decreased metabolic rates in VSMC from SMIRKO/ApoE-/- compared to ApoE-/- mice. Overexpression of IR in VSMCs increased ECAR and OCR, which were further stimulate by insulin, only in VSMC with IR. [J1] Insulin increased expressions of glycolytic enzymes including hexokinase 2 and phopshofructose kinase in VSMCs overexpressing IR. These findings have identified the importance of IR on the regulation of glycolysis and mitochondrial metabolism in VSMC, which could increase the stability of the atherosclerotic plaques by increased VSMCs proliferation and ECM, but reduced their apoptosis and productions of inflammatory cytokines. [J1]Hard to understand⋯maybe combine with the next phrase?

Disclosure

Q.Li: None. J.Fu: None. K.Park: None. Q.Li: None. G.L.King: Advisory Panel; Medtronic, Research Support; Janssen Pharmaceuticals, Inc.