bluuebunny/crossref_metadata_2025 huggingface dataset:
Recycling of Poly (Methyl Methacrylate) Waste Sheets to Synthesize Catalyst-Free Bi- Functional Cation Exchange Resin for Sequestering of Toxic Pollutant
Authors: Arif Ruba , Ali Syed Wasim , Saifullah Muhammad , Shahida Shabnam , Iqbal Sajid
Published: February 2024

A simple and green method for the recovery of methyl methacrylate (MMA) has been developed by recycling waste sheets of poly (methyl methacrylate) without using any catalyst. The liquefaction yield was 97.33% while the purity of recovered MMA was up to 92%. The recovered monomer utilized for the synthesis of methylmethacrylate-copolymer-divinylbenzene at 20% cross-linking in the presence of different porogens (methyl isobutylketone, cyclohexane, toluene, and cyclohexanone) by suspension polymerization. The same copolymer was also synthesized but with different cross-linking percentages such as 4, 10, 15, 20, 25, 30, and 40% in the presence of a single porogen (methyl isobutylketone). Different copolymers having pore volumes in the range of 0.120 to 0.682 mL/g were obtained. The pendant –COOCH3 groups within the polymeric chain were converted to –COOH groups via acid hydrolysis, accompanied by the attachment of –SO3H groups to phenyl rings. FTIR, UV-Vis spectrometry and HPLC techniques were used for qualitative and quantitative analyses of–COOH and –SO3H groups. The obtained results were compared with copolymers and resin synthesized using commercial MMA, displaying similar behavior. The resin derived from the recovered monomer was utilized for Co2+ ion removal at various pH levels, demonstrating excellent performance.
FUZRUF-onto: a Methodology to Develop Fuzzy Rough Ontologies
Authors: sanyour rawan
Published: February 2024

Nowadays, semantic web technologies play a crucial role in knowledge representation paradigm. With the raise of imprecise and vague knowledge, there is an upsurge demand in applying a concrete well-established procedure to represent such knowledge. Ontologies, particularly fuzzy ontologies are increasingly applied in application scenarios in which handling of vague knowledge is significant. However, such fuzzy ontologies utilize fuzzy set theory to provide quantitative methods to manage vagueness. In various cases of real-life scenarios, people need to express their everyday requirements using linguistic adverbs such as very, exactly, mostly, possibly, etc. The aim is to show how fuzzy properties can be complemented by Rough Set methods to capture another type of imprecision caused by approximation spaces. Rough sets theory offers a qualitative approach to model such vagueness via describing fuzzy properties at multiple levels of granularity using approximation sets. Using rough-set theory, each fuzzy concept is represented by two approximations. The lower approximation PL(C) consists of a set of fuzzy properties that are definitely observable in the concept. The upper approximation PU(C) on the other hand contains fuzzy properties that are possibly associated with the concept but may not be observed. This paper introduces a methodology named FUZRUF-onto methodology, which is a formal guidance on how to build fuzzy rough ontologies from scratch using extensive research in the area of fuzzy rough combination. Fuzzy set and rough set theories are applied to capture the inherently fuzzy relationships among concepts expressed by natural languages. The methodology provides a very good guideline for formally constructing fuzzy rough ontologies in terms of completeness, correctness, consistency, understandability, and conciseness. To explain how the FUZRUF-onto works, and demonstrate its usefulness, a practical step by step example is provided.
Interfacial thermal transport in combustion-dissociation process at different environments for methane hydrate
Authors: Meng Shuangshuang , Han Jihao , Yuan Kunpeng , Wang Zhaoliang
Published: February 2024

Currently, there is a considerable lack of research on the dissociation of methane hydrate combustion at the microscopic level. In this study, ReaxFF molecular dynamics simulations were used to accurately locate the phase transition interface during methane hydrate combustion-dissociation, and the interfacial heat transport was analyzed for different oxygen-fuel ratios and different combustion atmospheres. The time evolution of interfacial heat flux, interfacial thermal resistance and combustion production is extracted, finding that different ratios of oxygen-fuel and combustion atmospheres have different degrees of influence on the combustion-decomposition of hydrate. The larger ratio of oxygen-fuel, the greater the heat flux at solid-liquid interface, and the faster the dissociation rate of hydrate. Combustion is carried out more stably at the ratio of oxygen-fuel of 0.5. The value of solid-liquid interfacial heat flux at different atmospheres is O2/CO2 > O2/CH4 > O2. During the entire decomposition, the heat flux of burning boundary is greater than the solid-liquid interface under O2/CH4 atmosphere, lasting for about 1600 fs, which is 2.3 times than the pure O2 atmosphere. The heat flux of two interfaces at O2/CO2 atmosphere is the same, and the reactivity of CO2 plays a critical role in the decomposition driving of hydrate by reaction of CO2 + H→CO + OH at high temperature. The study reveals the heat and mass transfer mechanism of the combustion-dissociation process of methane hydrate under different combustion environments, which is of theoretical guidance for the stable combustion and controlled decomposition of hydrate.
Musical scales optimize pitch spacing: A global analysis of traditional vocal music
Authors: Brown Steven , Phillips Elizabeth , Husein Khalil , McBride John
Published: February 2024

The standard model of musical scales is derived from instrument tunings. However, the study of vocal scales – most especially in indigenous cultures – has been all but ignored. The voice is almost certainly the original musical instrument, and so an analysis of vocal scales provides a more naturalistic means of understanding the evolution of music. In particular, we explore the idea that the structure of musical scales is a reflection of the vocal imprecision inherent in the way that people sing, regardless of culture. To investigate this issue globally, we carried out a large-scale computational analysis of 418 ethnographic field recordings of vocal songs from indigenous/traditional cultures, spanning the 10 principal musical-style regions of the world. The results revealed that vocal scales have reliably larger intervallic spacings between pitch-classes than do instrumental scales in Western culture. In addition, the mean interval-size of the scales was significantly correlated with people’s imprecision in singing pitches across the world regions. These results lend support to a physiological model in which musical scales optimize pitch spacing in order to accommodate the imprecision inherent in vocal production and thereby maintain distinguishability between pitch-classes.
Unlocking the Enigma: Imagery and Meaning in Chinese Characters
Authors: feng lang
Published: February 2024

Phonetic characters neatly tie letters to pronunciation for recording speech sounds. Conversely, Chinese characters deviate from this phonetic simplicity, as their meanings veiled behind a mysterious ideological mechanism. Our analysis, spanning 9,000 regular script Chinese characters, unravels this enigma, revealing a rich tapestry of imagery encapsulating experiential events. Unlike their phonetic counterparts, Chinese characters refrain from direct sound representation. Instead, our findings illuminate a fascinating revelation—these characters employ imagery as metaphors to convey meanings. In essence, the structures themselves craft mental representations of experiences tied to word meanings. This intricate dance between structure and meaning forms a powerful ideological connection, facilitating our comprehension of word meanings. To systematically explore these visual metaphors, we establish four necessary conditions, adhering to scientific rigor and steering clear of unwarranted speculation. By collecting and analysing the meanings of characters sharing identical structures, we distill structural imagery that meets our stringent criteria. In conclusion, we identify the structural imagery underpinning 9,000 regular script Chinese characters and their intricate formations. Additionally, we outline five cognitive patterns governing their interactions. These revelations reveal the mechanism of ideogram formation in the Chinese language, offering a guiding theory for the nuanced study of Chinese word formation. Beyond theoretical significance, our research has practical implications, as it could enhance the efficiency of Chinese word acquisition.
Shining Through Shadows: Uncovering Barriers and Facilitators to Solar Energy Adoption in Commercial Enterprises
Authors: Dewi Lutfiana
Published: February 2024

This qualitative research delves into the multifaceted landscape of solar energy adoption in commercial enterprises, unveiling the intricacies of barriers and facilitators shaping businesses' transition towards sustainable energy practices. Through in-depth interviews and case studies, the study explores the interconnected themes of economic considerations, regulatory landscapes, technological readiness, organizational cultures, information and education, and collaboration and partnerships. Economic considerations play a pivotal role, with the upfront costs of solar installations acting as a significant barrier. However, businesses that successfully embrace solar power emphasize long-term economic benefits and return on investment as compelling facilitators. The regulatory landscape emerges as a critical factor, with supportive policies and clear regulations accelerating adoption, while ambiguity hampers progress. Technological readiness reflects the delicate balance between innovation, reliability, and perceived risks. Proactive sustainability-oriented cultures within organizational dynamics act as powerful facilitators, while resistance to change requires internal education and cultural transformation. Information and education serve as fundamental pillars, necessitating effective communication strategies and collaborative efforts for widespread awareness. Collaboration and partnerships are identified as key enablers, transcending individual businesses and fostering a supportive ecosystem. The study concludes that a holistic and collaborative approach, involving policymakers, industry stakeholders, and businesses, is essential for overcoming barriers and accelerating the transition to solar energy adoption.
Sémiotique sociale des plateformes éducatives et subjectivités enseignantes
Authors: Tréhondart Nolwenn , Carton Tiphaine
Published: February 2024

Dans le prolongement des travaux de Pierre Mœglin sur l’industrialisation de l’éducation (2006, 2016), notre propos s’inscrit dans le contexte de la diffusion grandissante d’une conception du numérique éducatif propagée par la filière française de la EdTech (Educational Technology). Nous présentons le contexte socioéconomique dans lequel opèrent les entreprises de la EdTech, puis nous introduisons des éléments de réflexion sur le concept de « plateforme éducative », au regard de travaux existants. Notre méthodologie, qui s’inspire de la sémiotique sociale (Saemmer et al., 2022), mobilise des concepts critiques issus de la sémiotique des écrits d’écran, couplés à une recherche-formation auprès d’enseignants. En prenant pour objet d’étude la plateforme d’apprentissage de la lecture Lalilo, nous montrons comment une démarche collective en sémiotique sociale peut les amener à réfléchir aux valeurs, normes et représentations du monde modélisées dans le design des plateformes éducatives, mais aussi à leurs propres représentations du numérique éducatif.
Pengaruh Kecepatan dan Persebaran Angin terhadap Kenyamanan Termal Aktivitas Berjalan Santai di Kawasan Taman Sari
Authors: Astuti Adindra Maharsi Kusuma , Amijaya Sita Yuliastuti
Published: February 2024

Title: The Impact of Wind Velocity and Distribution on Thermal Comfort during Leisurely Walking Activities in the Taman Sari Area
Urban Heat Island affects the thermal comfort of the microclimate of an area in the city and is a challenge for human adaptation and environmental sustainability. Taman Sari is a heritage tourism area in the center of Yogyakarta city. Wind speed is an important factor in the thermal comfort of outdoor space because the human body can directly feel the wind. This study aims to determine the effect of wind speed on thermal comfort in leisurely walking activities and determine the direction and distribution of wind in the Taman Sari area. The method used is descriptive quantitative to the results of field surveys, calculations, and simulation software Simscale. The research results are that wind speed influences thermal comfort when strolling, with the calculation that 1.3 m/s =< v < 3.7 m/s gives a comfortable perception in zones I and II. Meanwhile, in zone III, v =< 0.7 m/s, which gives the perception of heat. Simulation results show wind direction and validation of measurement data. The graphic pattern measurement data is the same as the graphical pattern of the simulated data. However, both data differ in wind speed values at several observation points.
STUDY OF OCULAR MANIFESTATIONS IN PATIENT WITH CHRONIC KIDNEY DISEASE IN TERTIARY CARE RURAL HOSPITAL
Authors:   PG Resident Department of Ophthalmology., S. Khamar Darshali , Bhandari Akshay ,   Professor and HOD Department of Ophthalmology.
Published: February 2024

Purpose: To study the occurrence of various ocular manifestations exhibited by patients with Chronic Kidney Disease(CKD) and to analyse the findings. Materials and Methods: An observational, cross sectional, descriptive study was conducted at a tertiary care hospital after the approval of ethical committee for duration of 1year (July 2022- July 2023). A total of 50 patients of all age group, either sex, diagnosed with CKD irrespective of the haemodialysis statuswere evaluated. Detailed history and examination including visual acuity, anterior segment andfundus examination with direct and indirect ophthalmoscope was conducted. Result:Majority of CKD cases were noted in the age group of more than 60 years (40%) with male predominance of 66%.Out of 50 cases, 13(26%) were hypertensives, 8(16%) were diabetics and 3 patients had both.Out of 50 patients,6(12%) and 13(26%) showed signs of hypertensive and diabetic retinopathy respectively. Retinal detachment was noted in 2 patients, one had signs of pathological myopia and vitreous hemorrhage was noted in 1 patient. Conclusion:Most patients of CKD are detected in advanced stages. Hence it becomes imperative to detect CKD at an early stageand retard the progress of renal disease. Eye can be used as a window to kidney status so that necessary treatment can be given before irreversible changes occur. Thus, early ocular screening is of utmost importance in such patients.
VISUAL OUTCOME AND EARLY POSTOPERATIVE COMPLICATIONS OF CATARACT SURGERY IN PATIENTS WITH DIABETES IN TERTIARY CARE HOSPITAL
Authors: Mohole Prachi , Jorvekar Shobhana
Published: February 2024

Purpose: To study the visual acuity outcomes and early complications of cataract surgery in patients with diabetes in tertiary care hospital. Materials and Methods: The research was conducted at the Ophthalmology Outpatient Department of Pravara Rural Medical Hospital, Loni. The data was drawn from patient records, focusing on individuals diagnosed with cataracts and known cases of Diabetes Mellitus (DM). Employing a descriptive longitudinal study design, the research encompassed a sample size of 110 individuals, selected through a purposive sampling method. The study spanned from June 2022 to June 2023. Result: The study included 110 patients. Diabetes leads to an increase in age-related cataract development more so in females. 6 weeks after the surgery 70% of patients had BCVA between 6/12-6/6, 20.9% of patients had BCVA between 6/24 and 6/18 and the remaining 9% had BCVA below 6/36. Anterior segment complications such as corneal edema, severe iritis, posterior synechiae, pupillary block, and pigmented precipitates on the IOL are more frequently observed. Conclusion: Enhancements in Best-Corrected Visual Acuity (BCVA) following the surgical intervention suggest that cataract surgery holds promise in effectively managing the visual challenges stemming from cataracts among diabetic patients.
ANTIFUNGAL EFFICACY OF SODIUM HYPOCHLORITE AND CHLORHEXIDINE WITH AND WITHOUT AN ANTIFUNGAL HERBAL IRRIGANT: AN INVITRO STUDY
Authors:   Head of Department, Department of Conservative Dentistry & Endodontics, KVG Dental College, Sullia, Karnataka., Krishna Prasada L. , C. Priya ,   Post Graduate Student, Department of Conservative Dentistry & Endodontics, KVG Dental College, Sullia, Karnataka.
Published: February 2024

Aim: The aim of this in vitro study was to evaluate the efficacy of 5.25% sodium hypochlorite (NaOCl) & 2% chlorhexidine gluconate (CHX) as a final irrigant with and without the inclusion of an antifungal herbal agent (Neem extract) on Candida albicans. Materials & Methods:Thirtyfive single-rooted premolars were instrumented and inoculated with a suspension of C. albicans. The experimental specimens were divided into two groups. The irrigant group was divided into 2 subgroups and irrigated with 5.25% NaOCl& 2% CHX respectively. The irrigant with antifungal group was divided into two subgroups and irrigated with 5.25% NaOCl& 2% CHX respectively followed by neem extract. The control group was irrigated with normal saline. Aliquots from the experimental teeth were plated on 4% Sabouraud agar, and the colony-forming units (CFUs) were evaluated under light microscopy (400x). Results: 2% CHX exhibited superior antifungal efficacy compared with 5.25% NaOCl with no significant difference. On inclusion of Neem extract, there was a significant decrease in the CFU 5.25% NaOCl and 2% CHX with Neem extract showed significantly greater antifungal properties. Conclusion: Neem extract proved to be effective against C. albicans when used along with root canal irrigants as a final rinse.
A STUDY TO EVALUATE THE EFFECTIVENESS OF VIDEO ASSISTED TEACHING PROGRAMME ON DISASTER MANAGEMENT AMONG GNM STUDENTS IN SMT. NAGARATHNAMMA SCHOOL OF NURSING, BENGALURU
Authors: Bano Shahida , Nanjappan Prof. Devi , Ghosh Saheli , Samanta Purnima , Barman Puja , Hossain Shahid
Published: February 2024

Background:A study to evaluate the effectiveness of video assisted teaching programme on disaster management among GNM students in Smt. Nagarathnamma school of nursing. To determine the pre-test knowledge among the students of Smt. Nagarathnamma School of Nursing at Bengaluru.To evaluate the effectiveness of video assisted teaching programme on disaster management.To find the association between the pretest level of knowledge scores of students with selected demographic variables Methods: A cross sectional survey method was used to collect the data using a structured awareness questionnaire from 100 caregivers of mentally ill patients based on non- probability purposive sampling.at Bapuji Hospital, Davangere. Results: 1. The knowledge regarding disaster management among students in pre-test, the mean score was 20.18 and standard deviation was 1.826. 2. The effectiveness of structured teaching programme have been evaluated and found effective with highly statistically significant values, (such as mean score = 31.26, standard deviation=1.826 and the t value=42.375with the p value= <0.05). 3. There was no significant association between the pre-test knowledge of the students with the demographic variables namely age, sex, educational qualification. Conclusion:This study has proved that the students had a remarkable increase in the knowledge regarding disaster management, when compared to their previous knowledge, prior to the administration of the structured teaching programme. This study plays an important role in prevention and management of impact in various disasters. This study has not only improved the knowledge of the students. It could be considered as a part of continuing professional development of students in all aspects.
PHYSICAL ACTIVITY IN PRIMARY SCHOOLS: A KEY MEDICINE TO HEALTH PROMOTION IN ETHIOPIA
Authors:   PhD Scholar, Shanghai University of Sport, China & Lecturer, Sport Science Department, Arba Minch University, Ethiopia., Debebe Mulugeta , Wu Yi-Gang ,   Professor, School of Physical Education and Sports Training, Shanghai University of Sport, China.
Published: February 2024

Engaging in physical activity within school settings improves early adolescents overall health status as well as their academic achievements. Therefore, the current study, aimed at primary schools, has been considered an essential medicine for promoting physical activity among older children. Eight hundred thirty-five older children aged 11 to 14 with a mean age of 12.95 Â±0.937 SD were selected. A cross-sectional study was utilized to achieve the objective of this survey. Self-reported PAQ-C measure was conducted. The PAQ-C survey was analyzed using IBM SPSS (Ver. 26) to achieve this studys intended physical activity goal. The internal coherence of the data was assessed by Cronbachs alpha (0.819). The finding indicated a low level of participation with an average mean score of 2.49 (SD 0.63). A significant mean difference was observed between grades five and eight with 0.18461 (CI = 0.0066, 0.3626), P-value = 0.039<0.05), and Kola Shara primary school had the most significant mean difference (mean value = 0.78975, P = 0.000<0.05). As a result, grade five was more active than grade level, and Shara Primary School had better participation. However, the overall composite mean score was below the average. Therefore, the study demonstrated low participation in physical activity among the selected schools in the Gamo zone, southern Ethiopia. Finally, the study suggests that further research is needed to understand the factors that hinder the promotion of physical activity in school settings.
CERVICAL CANCER AWARENESS, SCREENING AND VACCINATION AMONG FEMALE NURSING STUDENTS OF UNIVERSITY OF GHANA
Authors:   Department of Obstetrics and Gynaecology, University of Ghana Medical School, Korle-Bu, Accra, Ghana., Mumuni Kareem , Kyeremeh Gifty ,   Department of Obstetrics and Gynaecology, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana., Asah-Opoku Kwaku ,   Department of Obstetrics and Gynaecology, University of Ghana Medical School, Korle-Bu, Accra, Ghana., Abdullah Mensah Ishak ,   Department of Obstetrics and Gynaecology, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana., Adjoa Ohenewa Koranteng ,   Department of Obstetrics and Gynaecology, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana., Amma Duodua Maame ,   Department of Obstetrics and Gynaecology, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana., Atsu Gidisu Kelvin ,   Department of Obstetrics and Gynaecology, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana., Ali Samba ,   Department of Obstetrics and Gynaecology, University of Ghana Medical School, Korle-Bu, Accra, Ghana.
Published: February 2024

Background: Cervical cancer is a major cause of morbidity and mortality in developing countries despite been largely preventable. Late detection as a result of lack of awareness and access to care including non-availability of comprehensive care centres, lack of mass screening programs compounded by financial constraints, continue to keep the numbers high. This study looked at the level of awareness and practices of female nursing students of University of Ghana on cervical cancer, screening and vaccination. Methods: This was a descriptive cross-sectional study among 258 female nursing students of University of Ghana using self-administered questionnaire via Google forms. Besides sociodemographic data, general and specific knowledge on cervical cancer as well as screening and vaccination uptake data was collected. Results analysed with SPSS version 26. Means and standard deviations were used for continuous data and chi square for categorical data. A p-value of less than or equal to 0.05 was considered as statistically significant. Results: The knowledge level was fair among 73.6% of the respondents. The prevalence rate of cervical cancer screening and HPV vaccination was 19.0% and 6.2% respectively. Common reasons given for non-screening and non-vaccination were limited information on cervical cancer including unawareness of vaccine, not been sexually active and high cost of vaccine. There was significant association between screening uptake and vaccination uptake, though no association between knowledge and both screening and vaccination uptake. Conclusion: The knowledge level on cervical cancer was fair among female nursing students, however the prevalence of screening and vaccination were very low.
INCIDENCE OF HYPOCALCEMIA FOLLOWING NEAR TOTAL THYROIDECTOMY AND TOTAL THYROIDECTOMY
Authors:   MS (General Surgery), Assistant Professor, Department of General Surgery, ESIC Medical College and Hospital, Kalaburagi, Karnataka., Nikhil Vanura Koli , Kumar T. Arun ,   MS (General Surgery), Professor, Department of General Surgery, ESIC Medical College and Hospital, Kalaburagi, Karnataka.
Published: February 2024

Objective:Our study was conducted at ESIC Medical College and Hospital, Kalaburagi, aimed to evaluate the incidence of hypocalcemia following near-total and total thyroidectomy over a 2-year period from November 2021 to November 2023. Methods: A total of 120 patients above 12 years undergoing thyroidectomy were included. Pre-operative assessments, including clinical history, examination, fine needle aspiration cytology, thyroid function tests, ultrasound neck, and indirect laryngoscopy, were conducted. Blood samples were collected pre-operatively and post-operatively. Hypocalcemia was defined as serum calcium below 8 mg/dL and ionized calcium below 4.4 mg/dL, with transient hypocalcemia lasting less than 6 months and permanent hypocalcemia persisting beyond 6 months. Biochemical and laboratory tests, including thyroid function tests, were performed, and management involved calcium supplementation with or without vitamin D. Results: The study revealed an overall incidence of hypocalcemia at 21.6%, with 7.5% progressing to permanent hypocalcemia. Malignancy was more prevalent in males (60%), while benign disorders were common in females (60% in the age group 20-50 years). Conclusion: Postoperative hypocalcemia, though a frequent complication after near-total and total thyroidectomy, can be mitigated through proper planning, meticulous surgical techniques, and the use of advanced technologies. Regular monitoring and early intervention are imperative for patient well-being, emphasizing the importance of attention to surgical details in minimizing complications.
LAJOUT PRECOCE DE LAMOTRIGINE ET DARIPIPRAZOLE A LA CLOMIPRAMINE DANS LE TOC SEVERE
Authors:   Equipe de Recherche Pour la Sante Mentale, Service Univertaire Psychiatrique Hopital Ibn Nafis, CHU Mohamed VI, Marrakech., Fellah Sara El , Ghizlane Ezzahhar ,   Equipe de Recherche Pour la Sante Mentale, Service Univertaire Psychiatrique Hopital Ibn Nafis, CHU Mohamed VI, Marrakech., a Adaliimane ,   Equipe de Recherche Pour la Sante Mentale, Service Univertaire Psychiatrique Hopital Ibn Nafis, CHU Mohamed VI, Marrakech., b Manoudifatiha ,   Equipe de Recherche Pour la Sante Mentale, Service Univertaire Psychiatrique Hopital Ibn Nafis, CHU Mohamed VI, Marrakech.
Published: February 2024

La lamotrigine et laripiprazole ont montre leur efficacite en tant quagents daugmentation des inhibiteurs de la recapture de la serotonine pour le traitement. trouble obsessionnel-compulsif (TOC) resistant au stress. A ce jour, lefficacite de laugmentation de lamotrigine/aripiprazole a ete na pas ete rapporte dans le traitement du TOC. Nous rapportons ici le cas dun homme de 37 ans atteint de TOC severe et de comorbidites. depression dont les symptÃ´mes se sont nettement ameliores apres une augmentation de faibles doses de lamotrigine/aripiprazole par la clomipramine. Notre rapport suggere quune augmentation glutamatergique/antipsychotique precoce contribue a une remission rapide des symptÃ´mes du TOC.
GENOMIC ANALYSIS OF AN OUTBREAK ISOLATE OF SALMONELLA ENTERICASEROVARENTERITIDIS ST11 FROMCAYAR, SENEGAL
Authors:   Pole de Microbiologie, Institut Pasteur de Dakar, Senegal., Dieye Yakhya ,   Groupe de Recherche Biotechnologies Appliquees et Bioprocedes Environnementaux (GRBA-BE), Ecole Superieure Polytechnique, Universite Cheikh Anta Diop, Dakar, Senegal., Bousso Gueye Adja ,   Pole de Microbiologie, Institut Pasteur de Dakar, Senegal., Sow Ousmane ,   Pole de Microbiologie, Institut Pasteur de Dakar, Senegal., Sankhe Safietou ,   Pole de Virologie, Institut Pasteur de Dakar, Senegal., Kane Mouhamed ,   Pole de Virologie, Institut Pasteur de Dakar, Senegal., Aliou Barry Mamadou , Faye Martin ,   Pole de Virologie, Institut Pasteur de Dakar, Senegal., Moise Diagne Moussa ,   Pole de Virologie, Institut Pasteur de Dakar, Senegal., Sambe Ba Bissoume ,   Pole de Microbiologie, Institut Pasteur de Dakar, Senegal., Loucoubar Cheikh ,   Pole dEpidemiologie, de Recherche Clinique et de Science des Donnees, Institut Pasteur de Dakar, Senegal., Diop Boly ,   Division de la Surveillance, Ministere de la Sante et de lAction Sociale, Dakar, Senegal., Faye Ousmane ,   Pole de Virologie, Institut Pasteur de Dakar, Senegal., Fall Cheikh ,   Pole de Microbiologie, Institut Pasteur de Dakar, Senegal.
Published: February 2024

Salmonella enterica is a bacterial species that groups +2,600 serotypes, many of which being capable of infecting humans and animals. Salmonella infects its hosts by the oral route, and causes two types of diseases, a gastroenteritis and an invasive infection. Salmonella gastroenteritis is a self-limited infection that is restricted to the gastrointestinal tract, and is frequent worldwide. In contrast, invasive salmonellosis is a systemic, life-threatening disease that is mostly found in low-and-middle income countries (LMIC) where Salmonella transmission is favored by poor hygiene conditions. In Senegal, like in other sub-Saharan African countries, Salmonella gastroenteritis outbreaks are frequent, and, in many cases, investigations, when conducted, are typically limited to isolating, identifying and performing antimicrobial susceptibility testing. In this study, we used a whole genome sequencing approach to conduct a genomic characterization of a Salmonella enterica outbreak in Cayar, a coastal town located 40 km from Dakar, capital of Senegal. Our results showed that the responsible clone belonged to a global epidemic group of serovarEnteritidis isolates that are frequently associated with gastroenteritis in various countries worldwide.
HEMATOLOGICAL CHANGES INDUCED BY IMIDACLOPRID IN CLARIAS BATRACHUS (MAGUR)
Authors:   Research Scholar, Department of Zoology, Govt. Holkar (Model, Autonomous) Science College Indore., Tokriya R.K. , Billore K. ,   Assistant Professor, Department of Zoology, Govt. Holkar (Model, Autonomous) Science College Indore.
Published: February 2024

Imidacloprid is a Neonicotinoid pesticide extensively utilized in Indian agriculture to manage insect pests.Its water solubility and systemic nature are widely acknowledged to present a risk of contaminating adjacent water bodies.The main objective of this study was to evaluate the effects of Imidacloprid pesticide on the hematological parameters of Clarias batracus. In a controlled experimental setting, various sub-lethal concentrations (3, and 4 ppm) of Imidacloprid were administered at different time intervals. The impact of the pesticide was more pronounced in the short-term experiments. Hematological alterations were observed in the fish blood, where the hemoglobin (Hb), Red blood cells (RBCs), Packed cell volume (PCV), Mean corpuscular volume (MCV) and Mean Corpuscular Haemoglobin(MCH) declined with increasing concentrations, while the white blood cells (WBCs) increased under the same conditions.The results demonstrate statistical significance at the P < 0.05 level. These findings demonstrate that Imidacloprid can lead to significant variations in the hematological characteristics and induce a certain level of stress in fish. Therefore, the hematological factors of fish could serve as a sensitive tool for assessing their health status.
IMPACT OF EMERGENCY FOOD TEMPERATURE AND PRIVACY ON THE STRESS OF LIVING IN AN EVACUATION CENTER
Authors:   Health and Safety Sciences, Osaka Kyoiku University, Japan., Goto Kensuke , Sawada Yoshino ,   Sumitomo Life Insurance Company, Japan.
Published: February 2024

This study investigated the impact of emergency food temperature variation andthe presence of privacyon stress with the aim of potentially reducing the stress of living in an evacuation center during large-scale disasters. Salivary amylase activity of the subjects was measured. Results showed no statistically significant impact on stress due to variations in the temperature of emergency food or privacy. However, the survey noted points for improvement, including experiment settings and relationships between subjects, which highlighted the need for future research and surveys. This study is expected to aid with initiatives that reduce stress in evacuation centershowever, more detailed condition settings are required in order to eliminate individual stress level differences.
OBESITY AND URINARY INCONTINENCE
Authors:   Department of Obstetrics & Gynecology, Latifa Hospital, Dubai Health, Dubai, UAE., Yahya A. Alhubaishi Laila , Abdullatif Alhashemi Afaf ,   Department of Family Medicine Mankhool Dubaihealth, UAE & Department of Medical Education Dubai., M. Azim Faiqah ,   Department of Obstetrics & Gynecology, Latifa Hospital, Dubai Health, Dubai, UAE.
Published: February 2024

Urinary incontinence, the involuntary leakage of urine, is oftenunderdiagnosedandundertreated.Urinaryincontinenceaffectsalmost 50% of middle-aged and older women worldwide andaffectsthequalityoflifeseverely.Several risk factors have been attributed to urinary incontinence,obesity is an independent risk factor for stress-related and mixedurinary incontinence and is the most important risk factor for dailyurinaryincontinencecomparedtoanyotherfactor.Incontinence predisposes patients to other health problems, contributes todepression and social isolation, and is a significant source of dependencyamongtheelderly,Studies show that each 5-unit increase in body mass index (BMI) isassociated with a 60 â€“100% increased risk of daily urinary incontinence.This paper explores the relationship between obesity and urinaryincontinence, emphasizing obesity as an independent risk factor and acriticalcontributortostress-relatedandmixedurinaryincontinence.The review delves into the potential mechanisms linking obesity tourinary incontinence, highlighting the impact of excess body weightonpelvicfloor structures.
A STUDY ON THE IMPACT OF MOBILE BANKING ON CONSUMER SATISFACTION IN EMERGING MARKETS
Authors:   Associate Professor, Department of Economics, D.T.S.S College of Commerce and Research Centre, Malad (East), Mumbai., Noaman Umer Khatib , John Kesavapattapa Rebecca ,   Research Scholar, D.T.S.S College of Commerce and Research Centre, Malad (East), Mumbai.,   Assistant Professor at K J Somaiya College of Arts and Commerce, Vidyavihar (East), Mumbai.
Published: February 2024

Introduction: The research addresses the impact of mobile banking on consumer satisfaction in emerging markets, investigating adoption patterns, usage trends, and demographic influences. Against the backdrop of a rapidly evolving financial landscape, understanding the dynamics of mobile banking is crucial for optimizing services and fostering financial inclusion. Methods: The study employed a convenience sampling method, recruiting 150 participants from diverse backgrounds. Utilizing Likert scale questions, the research assessed mobile banking behaviors and satisfaction levels. The One-Way ANOVA (Welchs) and Independent Samples T-Tests were applied to analyze age and gender influences on adoption and satisfaction. Results: Key findings reveal a high frequency of mobile banking usage, positive perceptions of accessibility, ease of use, and security. Age emerged as a significant factor influencing adoption patterns and satisfaction levels. Statistical analyses indicated a notable difference in mean scores across age groups. Gender, however, did not exhibit a significant impact on mobile banking behaviors. Conclusion: The study concludes that mobile banking holds substantial promise for enhancing consumer satisfaction in emerging markets. Age-specific strategies are recommended for targeted marketing and outreach. The findings contribute valuable insights for financial institutions, policymakers, and researchers navigating the dynamic landscape of mobile banking in emerging economies.
SPERMATIC DNA FRAGMENTATION INDEX OF INFERTILE MEN: INTEREST IN THE CHOICE OF PMA TECHNIQUE PRELIMINARY STUDY
Authors:   Biochemistry Laboratory, Faculty of Pharmacy, Felix Houphouet University Boigny Abidjan, Cote dIvoire, BP V34 Abidjan., Mireille Yao-Yapo Carine , Kouame-Dia Chantal ,   Biochemistry Laboratory, Faculty of Pharmacy, Felix Houphouet University Boigny Abidjan, Cote dIvoire, BP V34 Abidjan., Benedicte Kone-Dakouri Yekayo ,   Biochemistry Laboratory, Faculty of Pharmacy, Felix Houphouet University Boigny Abidjan, Cote dIvoire, BP V34 Abidjan., Laure Hauhouot-Attoungbre Marie ,   Biochemistry Laboratory, Faculty of Pharmacy, Felix Houphouet University Boigny Abidjan, Cote dIvoire, BP V34 Abidjan.
Published: February 2024

Introduction: Infertility constitutes a real public health problem. In men, the examinations involved in the choice of the PMA technique are sometimes insufficient in relation to the real procreation potential of the spermatozoa which could be detected by the sperm DNA fragmentation test. This preliminary study aimed to highlight the benefit of taking into account the sperm DNA fragmentation test in the choice of the proposed PMA technique. Material and Methods: This was a preliminary descriptive cross-sectional study carried out in a private spermiology laboratory in Abidjan. It included 52 patients who came for consultation for infertility and who gave their written consent to participate in the study. Spermogram, spermocytogram, migration survival (TMS) test and DNA fragmentation index were studied. The DNA fragmentation index (DFI) was determined by the Sperm Chromatin Dispersion (SCD) technique. Results: The majority of patients were aged between 35 and 45 years (47%) with an average age of 45 years (+/-8). The most common spermogram abnormalities were mobility abnormalities. 52% of patients had a high fragmentation index. A high fragmentation index was found in a patient with normal sperm standard parameters. Likewise, 8 patients for whom intrauterine insemination had been recommended according to the TMS result had a fragmentation index greater than 30%. Conclusion: The first-line request for the fragmentation index in the exploration of male infertility must be studied since it could take into account the integrity of the genetic material, a limiting factor in the current tests used for the choice of the PMA technique.
ROLE OF DESHA IN DECIDING DIET AND LIFESTYLE
Authors:   P.G. Scholar Department of Kriya Sharir, National Institute of Ayurveda (Deemed to be University), Jaipur., a Deepshikha , Yadav C.R. ,   Professor, Dean (Research) & HOD, Department of Kriya Sharir, National Institute of Ayurveda (Deemed to be University)., Yadav Sarika ,   Assistant Professor, Department of Kriya Sharir, National Institute of Ayurveda (Deemed to be University), Jaipur.
Published: February 2024

Introduction: In Ayurveda, the traditional system of medicine that originated in ancient India, the concept of Desha (region or country) plays a crucial role in understanding lifestyle and diet. Ayurveda recognizes that the natural and environmental factors of a specific region significantly influence the physical and mental constitution of individuals.Acharya Charakareferred to the patients habitat as well as the land by using the name Desha. Acharya Vagbhata listed the 10 examinable elements for Desha and said that a doctor who thoroughly studies these will never hesitate to determine the proper medication for treating an aggravated Dosha. Understanding Desha is required for a complete assessment of the patient and the medication. Material & Methodology:Ayurvedic classics, commentaries, modern literature, research journals available in the institute library, and online resources were all used for inspiration for framing conceptual work. Discussion:Recognising Desha provides assistance not just with medication selection but also with patient examination and disease diagnosis. Everyone needs to be aware of its many practical elements. Applied aspect of Desha includes Role of Desha in health maintenance- SwasthasyaSwasthRakshanam& Role of Desha in Disease- AturasyaVikaraPrashaman. Conclusion:Pursuant to the current investigation, Desha affects a persons food and way of life from conception to death. From a health and illness perspective, Sadharana Desha is typically better than Anupa and Jangala Desha. These days, there is a lot of research being done on the gut microbiota, which highlights how crucial Desha is to leading a healthy life. Thus, this idea of Desha/ land/ locality/ place/ geographical area is crucial and need to be considered while organizing patient care or research projects, framing the policies too.
Role and Responsibilities of Various Stakeholders in Pharmacovigilance
Authors: Phougat Pinki , Beniwal Meenu , Kapoor Garima , Aggarwal Navidha , Kumari Aanchal , Sharma Rashmi , Chopra Hitesh , Sharma Rohit , Kamal Mohammad Amjad
Published: February 2024

:

In this review paper, we have analyzed the potential and issues associated with Pharmacovigilance
(PV). The analysis is divided into four sections: background, stakeholders, data sources,
and medicinal chemistry. Each section discusses the current state, the future trends, and the best practices
of Pharmacovigilance (PV). The main purpose, methods, results, and implications of our analysis
are summarized.

Background:

PV is the science and practice of monitoring, evaluating, understanding, and preventing
adverse drug reactions. PV was established by the World Health Organization in response
to the thalidomide tragedy of 1961. The main purpose of PV is to ensure the safety and efficacy of
drugs in clinical practice.

Stakeholders:

PV involves various stakeholders, such as patients, pharmacists, pharmaceutical
companies, healthcare professionals, and regulatory authorities. Each stakeholder has a different
role and responsibility in reporting, processing, analyzing, and communicating information
about adverse drug reactions. Patient engagement is a key factor for enhancing PV practices.

Data Sources:

PV relies on data from various sources, such as clinical trials, spontaneous reports,
electronic medical records, biomedical literature, and patient-reported data in online
health forums. These data sources can provide valuable insights into the real-world use and
safety of drugs, as well as the preferences and needs of patients. However, these data sources
also pose challenges in terms of quality, validity, reliability, and accessibility.

Medicinal Chemistry:

Medicinal chemistry is the branch of chemistry that deals with the design,
synthesis, and evaluation of new drugs and their biological effects. Medicinal chemistry can enhance
PV practices by finding new therapeutic indications for existing drugs or compounds that have already
been tested for safety and efficacy. Medicinal chemistry also requires careful design and evaluation
of covalent inhibitors, bi-substrate inhibitors, stabilizers of protein non-effective conformations,
and hydrophobic pocket modifiers to ensure their safety and efficacy.

Implications:

PV is a dynamic and evolving discipline that requires collaboration, regulation,
education, and innovation to improve patient safety and care. This review aims to provide a
comprehensive overview of the potential and issues associated with PV practices.
Ethnomedicinal Value of Medicinal Plants Found In Chhattisgarh: Recent Scenario and Advancement
Authors: Pandey Ravindra Kumar , Jain Parag , Shukla Shiv Shankar , Gidwani Beena , Jain Akanksha , - Ajazuddin
Published: February 2024

Traditional plant-based medicine in India exemplifies the culturally accepted connection
between natural medicines, health, diet, and folk healing. Plants and their derivatives are
increasingly used to treat illness because they are thought to be safe and effective medications
with few side effects and low cost. Herbal medicine has long been the foundation of alternative
healthcare and a primary inspiration for the development of novel pharmaceuticals. Medicinal,
aromatic, and dye plants with significant social, economic, and commercial value are stored in
Chhattisgarh. The current review article is an ethnobotanical study of medicinal plants used in
traditional medicine in the Chhattisgarh region of India. This review article includes data on the
plant species, plant parts, preparation process, and medicinal uses of traditional plants. Information
about medicinal plants was gathered from journals, textbooks, periodicals, websites, and
databases. The plant species discussed in the article have been widely utilized in Chhattisgarh,
India to prevent and treat a wide range of diseases.
The Perspective of Unani Medicine in Understanding Melasma – A Review
Authors: Horti Arshan , Husain Nazim , Shaikh Shalina , Imran Shaikh , Abbas Shaikh Nisar Ahmed , Khan Khan Ameer Kouser
Published: February 2024

Melasma, a prevalent hyperpigmentation skin disorder, poses significant challenges in
dermatology clinics. Despite its global impact, conventional treatment options often entail potential
side effects and limitations, necessitating the search for alternative therapeutic strategies.

:

This narrative review aims to advance the understanding of melasma from the perspective of
Unani medicine, an ancient healing system recognized by the World Health Organization. It seeks
to explore potential therapeutic avenues within the Unani medical paradigm by synergizing ancient
wisdom with contemporary perspectives.

:

The review delves into the Unani scholars' understanding of melasma, known as Kalaf, drawing
from the wisdom of renowned scholars. Their insights into the multifactorial etiology of melasma,
including pathogenesis, treatment approach, and recommended prescriptions, are discussed.

:

The descriptions of melasma by Unani scholars have documented the etiopathogenesis, risk factors,
and management in detail and emphasize personalized interventions based on the pathological
concepts of Unani medicine. Moreover, some of these interventions were also investigated in
recent clinical trials and found to have comparable efficacy with standard treatment options.

:

This review fosters the understanding of the pathogenesis of melasma according to Unani concepts
and a holistic approach to the management of melasma, drawing from the timeless legacy
of the Unani system of medicine. This review may serve as a reference point for future research,
enabling the planning of subsequent studies on this disease with a comprehensive understanding
of the previous investigations conducted in this field.