bluuebunny/crossref_metadata_2025 huggingface dataset:
Research Progress on the Application of Magnetic Nanomaterials in Water
Pollution Control
Authors: Li Xiang , Xie Shiyu , Zeng Guoming , Khan Sarfaraz
Published: March 2022

With the increasing shortage of water resources and the improvement in people's awareness
regarding environmental protection, the traditional water pollution control technology cannot
meet the needs of the development of environmental protection. In recent years, the rapid development
of nanotechnology and nanomaterials has provided a good opportunity for the innovation of
water treatment technology and has attracted the extensive attention of many environmental researchers.
In particular, new functional magnetic nanomaterials with good adsorption properties,
good chemical stability, easy regeneration, and easy solid-liquid separation have become hot topics
in the field of water pollution control. This paper aims to provide the present research progress of
magnetic nanomaterials in water pollution control, including the striking characteristics and preparation
methods of the most well-known magnetic nanomaterials, as well as their applications in the water
pollution control field. Concluding remarks and future trends have also been pointed out.
Effects of Combined Pure Cultures of Rhizopus sp. (Rhizopus oryzae,
Rhizopus oligosporus, and Rhizopus stolonifer) on Tempeh Extract Yogurt
as a Functional Food
Authors: Yarlina Vira Putri , Astuti Dea Indriani , Djali Mohammad , Andoyo Robi , Lani Mohd Nizam
Published: March 2022

Background:

Tempeh Extract Yogurt was an alternative to tempeh product development that can be used as a functional product. This study aimed to determine the functional food potential of yogurt with tempeh extract by including tempeh using mixed cultures.

Methods:

The ratio of making tempeh Rhizopus oryzae, Rhizopus oligosporus, Rhizopus stolonifer inoculum of 1:1:1, 1:2:1, 2:1:2, 1:1:2, 2:1:1, respectively; RAPRIMA tempeh starter as a control group was fermented with Lactic Acid Bacteria to produce tempeh extract yogurt.

Results:

Tempeh extract yogurt by SNI 2891:2009 with the characteristic’s thick liquid, specific aroma, sour taste, and homogeneous consistency. The highest form of vitamin B12 and folate in Tempeh Extract Yogurt was on a 1:2:1 ratio (0.072 g/100 mL and 0.059 g/100 mL), and the genistein isoflavone in RAPRIMA was 3.669 g/100 mL with a pH value of 4.2 and a total bacterium of 14,3 x 108 CFU/mL.

Conclusion:

Tempeh extract yogurt contains several vitamin B12, folate, isoflavones, and total bacteria Tempeh Extract Yogurt be responsible as a functional food.
Maternal Nutritional Factors, Fetal Macrosomia and Increased Risk of
Childhood Obesity: Effects of Excess Placental Transfer of Maternal
Glucose and Fatty Acids
Authors: Kabaran Seray
Published: March 2022

Background:

Maternal nutritional factors play a significant role in maternal glucose
and fatty acid transfer across the placenta and contribute to further enhancing fetal growth and
also increasing the risk of fetal macrosomia.

Objective:

This review aims to provide the effects of placental transfer of maternal fatty acids
and glucose on fetal macrosomia, and also highlights the maternal nutritional interventions to
prevent fetal adiposity.

Method:

All abstracts and full-text articles have been examined and the most relevant articles
have been included in this review.

Results:

Maternal obesity, maternal over-nutrition, and gestational diabetes can permanently influence
the risk of macrosomia via the effects of the placental transfer of maternal fatty acids and
glucose on the fetus. These conditions are associated with unfavorable maternal environments
that lead to fetal growth acceleration by adverse fetal programming outcomes and increased risk
of childhood obesity. As a result, pregnancy should be viewed as a window of opportunity for
the development of maternal nutritional therapies that improve maternal glucose and lipid metabolism,
potentially reducing macrosomia and juvenile obesity.

Conclusion:

Evidence-based techniques for managing maternal glucose and fatty acid transfer to
the fetus include maintaining maternal pre-pregnancy body mass index (BMI), acceptable weight
gain throughout pregnancy, and maternal nutritional interventions during pregnancy. Healthy
dietary patterns (such as the Mediterranean diet) and/or dietary consumption of certain nutrients
(such as omega-3 fatty acids) are among the suggestions for fetal macrosomia prevention.
Design of Multitarget Natural Products Analogs with Potential Anti-Alzheimer’s Activity
Authors: da Silva Hage-Melim Lorane Izabel , de Souza Franciane Nunes , de Lima Henrique Barros , de Souza Lucilene Rocha , Oliveira Gabrieli Santos , de Paula da Silva Carlos Henrique Tomich , Pereira Arlindo César Matias
Published: March 2022

Background:

Alzheimer’s disease (AD) is a neurodegenerative condition and the most com-mon type of dementia among the elderly. The enzymes acetylcholinesterase (AChE) and nitric oxide synthase (NOS) have a pivotal role in the pathophysiology of this disease.

Objective:

This study aimed to select medicinal plant-derived molecules with reported inhibition of AChE and design optimized molecules that could inhibit not only AChE, but also NOS, potentially increasing its efficacy against AD.

Methods:

24 compounds were selected from the literature based on their known AChE inhibitory activity. Then, we performed molecular orbital calculations, maps of electrostatic potential, molecular docking study, identification of the pharmacophoric pattern, evaluation of pharmacokinetic and toxicological properties of these molecules. Next, ten analogs were generated for each molecule to optimize their effect where the best molecules of natural products had failed.

Results:

The most relevant correlation was between HOMO and GAP in the correlation matrix of the molecules’ descriptors. The pharmacophoric group’s derivation found the following pharmacophoric fea-tures: two hydrogen bond acceptors and one aromatic ring. The studied molecules interacted with the active site of AChE through hydrophobic and hydrogen bonds and with NOS through hydrogen interac-tions only but in a meaningful manner. In the pharmacokinetic and toxicological prediction, the com-pounds showed satisfactory results.

Conclusion:

The design of natural products analogs demonstrated good affinities with the pharmacolog-ical targets AChE and NOS, with satisfactory pharmacokinetics and toxicology profiles. Thus, the results could identify promising molecules for treating Alzheimer’s disease.
Comparison of energy parameters of electric storage systems for DC and AC traction power supply systems
Authors: Nezevak V. L.
Published: March 2022

Introduction. The article discusses the energy parameters of electric power storage systems for DC and AC traction power supply systems. The purpose of the research is to evaluate the energy parameters of electric power storage systems located within the inter-substation zone boundaries of the AC traction power supply system at the 25 kV voltage.

Materials and methods. The author used the methods of modeling, statistics and the experimental results processing. Moreover, the paper presented the parameter estimation of the energy accumulation system on the basis of the traction calculations for the AC rolling stock. In addition, the author made two variants of calculations — in the presence and the absence of the electric storage system. The researcher also made the simulation of the electric storage system for the voltage source connected to the sectioning post busbars.

Results. Using the simulation modeling, the author presents active and reactive power graphs of the inter-substation zone boundaries in the active sectioning post operation conditions. Therefore, the article demonstrates the graph of the expected charge, the discharge depth calculations for the nominal energy capacity and the required charging features, which guarantee the charge restoration of the accumulation system to the initial level.

Discussion and conclusion. The author offers the comparative assessment of the electric storage systems for the traction power supply with the DС voltage of 3 kV and the AC voltage of 25 kV. The research demonstrates the reducing potential of the nominal accumulation parameters.
Резонансная динамика намагниченности одноосной наночастицы
Authors: Шутый А.М. , Василевская Т.М. , Семенцов Д.И.
Published: March 2022

Analysis of equilibrium conditions was carried out and resonant precessional dynamics of magnetization of a single-domain magnetically uniaxial ellipsoidal particle. Сonsidered the case when magnetic field is along the easy magnetization axis. the easy magnetization axis is directed parallel to the axis of symmetry of the ellipsoid and transverse to pumping by a weak high-frequency field. Features of the behavior of the magnetization were discovered. It has been revealed that the magnetization has features of resonant behavior: large resonant precession angles with amplitude , elliptical deviations of the precession trajectory from circular at a negative value of the effective anisotropy field, and the presence of a frequency region with nonlinear precession for an oblate nanoparticle.
Моделирование акустической эмиссии и разрушения поликристаллических гетерогенных материалов методом дискретных элементов
Authors: Гиляров В.Л. , Дамаскинская Е.Е.
Published: March 2022

The discrete element method (DEM) is used to reveal the main features of the fracture in materials with different degree of heterogeneity. It is shown that this method adequately describes the main properties of materials in the fracture process such as brittle and ductile behavior, two-staged nature of fracture in heterogeneous materials, heterogeneity of the spatial distribution of local internal stresses depending on the degree of heterogeneity.
Влияние выдергивания графеновых пластин из керамической матрицы на трещиностойкость композитов керамика/графен
Authors: Бобылев С.В.
Published: March 2022

A theoretical model is proposed that describes the effect of graphene platelets pullout on the fracture toughness of ceramic/graphene composites. The dependences of fracture toughness on the graphene concentration and the dimensions of graphene platelets are calculated using a stabilized zirconium oxide (YSZ)/graphene composite as an example. Calculations predict that if graphene platelets pullout from ceramic matrix is the dominant mechanism, then the maximum fracture toughness is achieved in the case of the longest and thinnest possible graphene platelets, provided that the latter have sufficient strength and adhesion to the matrix. The model shows a good correlation with experimental data at low graphene concentrations.
A clinical case of atypical course and difficulties in diagnosing Hodgkin's lymphoma
Authors: Burtseva E. A. , Shatokhin Y. V. , Snezhko I. V. , Ryabikina E. V. , Gerasimova O. V.
Published: March 2022

Hodgkin's lymphoma (LH) is a B-cell malignant lymphoproliferative disease. There are no specific symptoms characteristic only for this disease. Here may be an asymptomatic increase in peripheral lymph nodes; symptoms of intoxication (B-symptoms — fever above 38 ° C for at least three consecutive days without signs of inflammation; night profuse sweats; weight loss by 10% of body weight over the past 6 months); intermittent fever; itching; in patients with massive mediastinal lesion — chest pain, cough, shortness of breath, symptoms of compression of the superior vena cava, with localization closer to the sternum, discomfort behind the sternum is possible. The presence of the formation of mediastenia and purulent process (abscess, phlegmons, osteomyelitis), resistant to surgery (autopsy, drainage, resection) and antibacterial therapy requires the exclusion of the neoplastic process. It is necessary to carefully observe the technique of performing biopsy and transporting material in a neutral formalin solution at an early date to the pathological - anatomical laboratory, in case of non-standard manifestations of the disease, revision of the biopsy material with mandatory immunohistochemical examination. It is important to bear in mind that the presence of comorbidity (obesity, hypertension, diabetes mellitus) creates additional objective difficulties in the diagnosis and treatment, and requires a collegial decision by a consultation of specialists in patient management tactics.
Legal regulation of disclosure of medical confidentiality in the light of legislative novelties of 2021
Authors: Samojlova Yu. B. , Berezin I. G. , Shepeleva Yu. L.
Published: March 2022

Authors consider topical aspects of keeping secret information of limited access, to which medical secrecy refers, as well as risks associated with their illegal communication to third parties. Particular attention in the article is paid to the issues of determining the limits of the lawfulness of disclosing medical secrecy, as well as the registration of the written consent of a citizen for such actions of medical personnel.
Teaching therapy in a pandemic: lessons and perspectives
Authors: Ponomareva E. Yu. , Dorogoikina K. D. , Rebrov A. P.
Published: March 2022

The article discusses the features of teaching clinical discipline (hospital therapy) in the special conditions of a pandemic, the possibility of combining full-time and distance learning, presents the experience of using distance technologies as an addition to traditional forms of teaching clinical discipline.
Efficacy of perindopril/amlodipine and valsartan/amlodipine combinations in patients with a combination of arterial hypertension and chronic obstructive pulmonary disease
Authors: Bubnova M. A. , Kryuchkova O. N. , Itskova E. A. , Lutai Y. A. , Turna E. U. , Jukova N. V. , Kostyukova E. A.
Published: March 2022

Objective: to study the comparative efficacy and safety of the use of perindopril/amlodipine and valsartan/amlodipine combinations in patients with a combination of arterial hypertension and chronic obstructive pulmonary disease. Materials and methods: 85 patients with a verified diagnosis of arterial hypertension and chronic obstructive pulmonary disease were examined, the average age of patients was 60.9±1.1 years; 54% of men and 46% of women who were prescribed two variants of combination therapy (group A amlodipine/perindopril, group B amlodipine/valsartan). At the first visit and 6 weeks after the start of therapy, all patients underwent clinical, laboratory and instrumental examinations in accordance with the current protocols for the treatment of hypertension and chronic obstructive pulmonary disease, a daily blood pressure study, the frequency of depressive disorders was assessed on the Beck scale and the quality of life according to the SF-36 questionnaire. Results: the use of both antihypertensive regimens in comorbid patients was accompanied by comparable antihypertensive efficacy of therapy, contributed to the same statistically significant decrease in daily, day and night blood pressure indicators. The analysis of the indicators of the function of external respiration revealed the absence of negative dynamics of spirographic indicators in both groups. The use of both combinations of antihypertensive drugs contributed to the statistically identical recovery of both physical and mental components of the patient's quality of life. The improvement in the quality of life of comorbid patients was accompanied by a decrease in the manifestations of depressive disorders in the studied patients according to the Beck scale. The average score of the Beck scale in patients of group A before treatment was 11.6±0.97, against the background of therapy — 9.1±0.77, p <0.001. In patients of group B, it decreased from 13.0±1.06 to 9.3±0.78, p <0.001. Conclusion: the use of antihypertensive combined strategies amlodipine / perindopril and amlodipine / valsartan for the treatment of hypertension in patients with chronic obstructive pulmonary disease is characterized by comparable effectiveness of blood pressure control, which is confirmed by the data of daily monitoring of blood pressure. Effective control of blood pressure was accompanied by statistically significant (p<0.001) positive dynamics of most indicators of the quality of life of patients in both study groups and the severity of manifestations of depression. Any of the studied combinations, which demonstrated comparable efficacy and tolerability in the study, can be recommended as the first step of antihypertensive therapy in patients with arterial hypertension in combination with chronic obstructive pulmonary disease.
Atrial fibrillation in old age: current treatment options
Authors: Kanorskii S. G.
Published: March 2022

In older age, patients with atrial fibrillation (AF) have a high risk of stroke, bleeding, and death, but such patients have been underrepresented in randomized clinical trials. A search and analysis of 4 176 literature sources from the MEDLINE/ PubMed  and eLIBRARY  databases  was carried out for the keywords  «atrial fibrillation», «old age», «older», «elderly». The review includes  the most important  studies reflecting  the current understanding of risk factors for development, complications and treatment of AF in old age. The results of therapy to control the ventricular rate, to control sinus rhythm in AF with  drugs  and  catheter  ablation  are discussed. The data of studies  on the prevention of thromboembolic complications in patients with AF by the use of anticoagulants and implantable devices are considered.
Telemedicine Acceptance Among Older Adult Patients With Cancer: Scoping Review
Authors: Pang Ning-Qi , Lau Jerrald , Fong Si-Ying , Wong Celine Yu-Hui , Tan Ker-Kan
Published: March 2022

Background

Cancer is likely to remain the most prevalent noncommunicable disease in high-income countries with an older population. Interestingly, no review of attitudes toward telemedicine among older adults has been performed. This is likely to be the group most affected by both cancer and the increasing use of technology in health care.

Objective

We aimed to map research on the acceptance of telemedicine among older adults who are cancer patients.

Methods

We conducted a scoping review. PubMed, EMBASE, PsycINFO, CINAHL, and the Cochrane Central Register of Controlled Trials were systematically searched from inception to September 2020. Articles were included if the study population had a mean or median age ≥65 years, with cancer diagnoses and if the study assessed patients’ acceptance of a telemedicine intervention. Quantitative, qualitative, and mixed method studies were included.

Results

Out of a total of 887 articles that were identified, 19 were included in the review. Interventions were delivered via telephone, videoconference, web portal, mobile app, wearable technology, and text messaging and included teleconsultation, monitoring and follow-up, psychosocial support and nursing care, and prompts. The most often cited facilitating factor was convenience. Other facilitators included an increase in telemedicine care accessibility, previous positive experiences of telemedicine, appropriate technical knowledge and support, decreased cost, physician recommendations, and privacy conferred by the telemedicine intervention. Barriers include a preference for conventional care along with negative perceptions of telemedicine, concerns about technical difficulties, and confidentiality concerns in the adoption of telemedicine.

Conclusions

None of the studies explored the ability of tailored interventions to address facilitators and barriers of the acceptance of telemedicine in order to increase its adoption by older adults. Facilitators and barriers will likely differ across different cultural contexts and by type of telemedicine; however, this is a gap in current knowledge. In-depth studies are necessary to determine if interventions could potentially address the barriers identified in this review, to increase acceptability.
The Volume and Tone of Twitter Posts About Cannabis Use During Pregnancy: Protocol for a Scoping Review
Authors: Cresswell Liam , Espin-Noboa Lisette , Murphy Malia S Q , Ramlawi Serine , Walker Mark C , Karsai Márton , Corsi Daniel J
Published: March 2022

Background

Cannabis use has increased in Canada since its legalization in 2018, including among pregnant women who may be motivated to use cannabis to reduce symptoms of nausea and vomiting. However, a growing body of research suggests that cannabis use during pregnancy may harm the developing fetus. As a result, patients increasingly seek medical advice from online sources, but these platforms may also spread anecdotal descriptions or misinformation. Given the possible disconnect between online messaging and evidence-based research about the effects of cannabis use during pregnancy, there is a potential for advice taken from social media to affect the health of mothers and their babies.

Objective

This study aims to quantify the volume and tone of English language posts related to cannabis use in pregnancy from January 2012 to December 2021.

Methods

Modeling published frameworks for scoping reviews, we will collect publicly available posts from Twitter that mention cannabis use during pregnancy and use the Twitter Application Programming Interface for Academic Research to extract data from tweets, including public metrics such as the number of likes, retweets, and quotes, as well as health effect mentions, sentiment, location, and users’ interests. These data will be used to quantify how cannabis use during pregnancy is discussed on Twitter and to build a qualitative profile of supportive and opposing posters.

Results

The CHEO Research Ethics Board reviewed our project and granted an exemption in May 2021. As of December 2021, we have gained approval to use the Twitter Application Programming Interface for Academic Research and have developed a preliminary search strategy that returns over 3 million unique tweets posted between 2012 and 2021.

Conclusions

Understanding how Twitter is being used to discuss cannabis use during pregnancy will help public health agencies and health care providers assess the messaging patients may be receiving and develop communication strategies to counter misinformation, especially in geographical regions where legalization is recent or imminent. Most importantly, we foresee that our findings will assist expecting families in making informed choices about where they choose to access advice about using cannabis during pregnancy.

Trial Registration

Open Science Framework 10.17605/OSF.IO/BW8DA; www.osf.io/6fb2e

International Registered Report Identifier (IRRID)

PRR1-10.2196/34421
Perception of the Food and Drug Administration Electronic Cigarette Flavor Enforcement Policy on Twitter: Observational Study (Preprint)
Authors: Lu Xinyi , Sun Li , Xie Zidian , Li Dongmei
Published: March 2022

BACKGROUND

On January 2, 2020, the US Food and Drug Administration (FDA) released the electronic cigarette (e-cigarette) flavor enforcement policy to prohibit the sale of all flavored cartridge–based e-cigarettes, except for menthol and tobacco flavors.

OBJECTIVE

This research aimed to examine the public perception of this FDA flavor enforcement policy and its impact on the public perception of e-cigarettes on Twitter.

METHODS

A total of 2,341,660 e-cigarette–related tweets and 190,490 FDA flavor enforcement policy–related tweets in the United States were collected from Twitter before (between June 13 and August 22, 2019) and after (between January 2 and March 30, 2020) the announcement of the FDA flavor enforcement policy. Sentiment analysis was conducted to detect the changes in the public perceptions of the policy and e-cigarettes on Twitter. Topic modeling was used for finding frequently discussed topics about e-cigarettes.

RESULTS

The proportion of negative sentiment tweets about e-cigarettes significantly increased after the announcement of the FDA flavor enforcement policy compared with before the announcement of the policy. In contrast, the overall sentiment toward the FDA flavor enforcement policy became less negative. The FDA flavor enforcement policy was the most popular topic associated with e-cigarettes after the announcement of the FDA flavor enforcement policy. Twitter users who discussed about e-cigarettes started to talk about other alternative ways of getting e-cigarettes after the FDA flavor enforcement policy.

CONCLUSIONS

Twitter users’ perceptions of e-cigarettes became more negative after the announcement of the FDA flavor enforcement policy.
The Volume and Tone of Twitter Posts About Cannabis Use During Pregnancy: Protocol for a Scoping Review (Preprint)
Authors: Cresswell Liam , Espin-Noboa Lisette , Murphy Malia S Q , Ramlawi Serine , Walker Mark C , Karsai Márton , Corsi Daniel J
Published: March 2022

BACKGROUND

Cannabis use has increased in Canada since its legalization in 2018, including among pregnant women who may be motivated to use cannabis to reduce symptoms of nausea and vomiting. However, a growing body of research suggests that cannabis use during pregnancy may harm the developing fetus. As a result, patients increasingly seek medical advice from online sources, but these platforms may also spread anecdotal descriptions or misinformation. Given the possible disconnect between online messaging and evidence-based research about the effects of cannabis use during pregnancy, there is a potential for advice taken from social media to affect the health of mothers and their babies.

OBJECTIVE

This study aims to quantify the volume and tone of English language posts related to cannabis use in pregnancy from January 2012 to December 2021.

METHODS

Modeling published frameworks for scoping reviews, we will collect publicly available posts from Twitter that mention cannabis use during pregnancy and use the Twitter Application Programming Interface for Academic Research to extract data from tweets, including public metrics such as the number of likes, retweets, and quotes, as well as health effect mentions, sentiment, location, and users’ interests. These data will be used to quantify how cannabis use during pregnancy is discussed on Twitter and to build a qualitative profile of supportive and opposing posters.

RESULTS

The CHEO Research Ethics Board reviewed our project and granted an exemption in May 2021. As of December 2021, we have gained approval to use the Twitter Application Programming Interface for Academic Research and have developed a preliminary search strategy that returns over 3 million unique tweets posted between 2012 and 2021.

CONCLUSIONS

Understanding how Twitter is being used to discuss cannabis use during pregnancy will help public health agencies and health care providers assess the messaging patients may be receiving and develop communication strategies to counter misinformation, especially in geographical regions where legalization is recent or imminent. Most importantly, we foresee that our findings will assist expecting families in making informed choices about where they choose to access advice about using cannabis during pregnancy.

CLINICALTRIAL

Open Science Framework 10.17605/OSF.IO/BW8DA; www.osf.io/6fb2e

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/34421
Authors' Response to Peer Reviews of “Measuring Integrated Novel Dimensions in Neurodevelopmental and Stress-Related Mental Disorders (MIND-SET): Protocol for a Cross-sectional Comorbidity Study From a Research Domain Criteria Perspective” (Preprint)
Authors: van Eijndhoven Philip , Collard Rose , Vrijsen Janna , Geurts Dirk E M , Vasquez Alejandro Arias , Schellekens Arnt , van den Munckhof Eva , Brolsma Sophie , Duyser Fleur , Bergman Annemiek , van Oort Jasper , Tendolkar Indira , Schene Aart
Published: March 2022

UNSTRUCTURED

These are author responses to peer review of ms#31269
Sensory Overresponsivity and Symptoms Across the Obsessive-Compulsive Spectrum: Web-Based Longitudinal Observational Study (Preprint)
Authors: Moreno-Amador Beatriz , Cervin Matti , Martínez-González Agustin Ernesto , Piqueras Jose A ,   OCD-Spectrum Spain Research Group
Published: March 2022

BACKGROUND

Sensory overresponsivity (SOR) has emerged as a potential endophenotype in obsessive-compulsive disorder (OCD), but few studies have examined SOR in relation to the major symptom dimensions of OCD and to symptoms across the full obsessive-compulsive (OC) symptom spectrum.

OBJECTIVE

This study had 2 main objectives. First, we examined the psychometric properties of the SOR Scales in a community-based sample of Spanish adolescents and adults. Second, we identified how SOR difficulties are related to symptoms across the full OC spectrum (eg, OC, body dysmorphic, hoarding, skin-picking, and hair-pulling symptoms), including the heterogeneity of OC symptoms.

METHODS

We translated the SOR Scales into Spanish—a measure that assesses SOR across the 5 sensory modalities—and created a web-based version of the measure. A sample of 1454 adolescents and adults (mean age 23.84, SD 8.46 years) participated in the study, and 388 (26.69%) participants completed the survey twice (approximately 8 months apart). The survey also contained a web-based measure that assesses symptoms across the full OC spectrum: harm and checking, taboo obsessions, contamination or cleaning, symmetry and ordering, body dysmorphic, hoarding, hair-pulling, and skin-picking symptoms.

RESULTS

The psychometric properties of the SOR Scales were excellent, and the test-retest reliability was adequate. All types of SOR were related to all major symptom dimensions of OCD and to all OC spectrum symptoms.

CONCLUSIONS

SOR across the sensory modalities can be validly assessed using a web-based measure. SOR emerged as a pure transdiagnostic phenomenon in relation to symptoms across the OC spectrum, with no specific sensory modality being more strongly related to OC symptoms. SOR can shed much needed light on basic mechanisms that are important for the onset and maintenance of OC spectrum symptoms, and this study shows that large-scale web-based studies can aid in this endeavor. Future studies should examine whether SOR precedes or emerges alongside OC symptoms.
A care-concept of community health nursing interventions for adults with chronic health conditions in an urban area: a study protocol of a randomized controlled field trial (CoSta study) (Preprint)
Authors: Nock Annike Morgane , Iversen Linda , Waidhas Lukas , Zapf Antonia , Seifert Caroline , Petersen-Ewert Corinna
Published: March 2022

BACKGROUND

Implementing community health nursing programmes is a new field of application in primary health sector in Germany. Hence, there is limited evidence of effective community-based and nurse-led interventions with regard to the German healthcare system. International research find-ings are mostly not transferable. The CoSta-project is the first study which examines a community health nurse-led intervention for adults with chronic health conditions.

OBJECTIVE

This study protocol describes the design and method of a randomized controlled trial in field which investigates if a community health nurse-based intervention has an impact on health-related quality of life in adults with chronic conditions.

METHODS

The study is designed as a randomized controlled trial under real-life conditions in field. In a four-month period, patients will be enrolled with at least one chronic ICD-10 diagnosis. Participants will be randomly allocated to an intervention or a control group. The maximum number of cases will be 130. The control group will be treated as usual. The intervention group will receive additionally to the treatment as usual preventive home visits, consultation and educative training offered by two community health nurses for up to 12 months.

RESULTS

Both groups will be followed up at baseline, after 6 and after 12 months. The primary outcome measure is the Mental Component Summary (MCS) score from the SF-36 questionnaire after 12-months. Secondary patient outcomes will be included. Ethical approval has been obtained. In secondary analyses the association of social factors influencing (education, income, employment) will be examined.

CONCLUSIONS

This study will provide data with regard to the effectiveness of community nurse-led interven-tions which focus on the treatment of vulnerable adults with chronic health conditions in the community health centre. We expect results which will help to reduce the research-to-practice gap.

CLINICALTRIAL

The study has been registered at German Clinical Trials Register, ID: DRKS00026164 on Septem-ber 10th, 2021. Funding: The CoSta project is funded by the Federal Ministery of Education and Research, con-tract number 13FH019SX8. We acknowledge support for the article processing charge by the Open Access Publication Fund of Hamburg University of Applied Sciences.
Assessing WHODAS 2.0 Scores from Behavioral Biomarkers: a Data-driven Approach (Preprint)
Authors: Sükei Emese , Romero-Medrano Lorena , de Leon-Martinez Santiago , Herrera López Jesús , Campaña-Montes Juan José , M. Olmos Pablo , Baca-Garcia Enrique , Artés Antonio
Published: March 2022

BACKGROUND

Functional limitations are associated with poor clinical outcomes, higher mortality, and disability rates, especially in the elderly. Continuous assessment of patients’ functionality is important for clinical practice; however, traditional questionnaire-based assessment methods are very time-consuming and infrequently used. Mobile sensing offers a great range of sources that can assess function and disability daily.

OBJECTIVE

This work aims to prove the feasibility of an interpretable machine learning pipeline for predicting WHODAS 2.0 outcomes utilizing solely passively collected digital biomarkers.

METHODS

One-month long time-series data were summarized using statistical measures (minimum, maximum, mean, median, standard deviation, IQR), creating 64 features. We then applied a sequential feature selection on each WHODAS 2.0 domain (cognition, mobility, self-care, getting along, life activities, participation). Finally, we predicted the WHODAS 2.0 functional domain scores using linear regression using the best feature subsets. We reported the mean absolute errors and the mean absolute percentage errors as goodness-of-fit statistics to evaluate the model.

RESULTS

Our machine learning-based models for predicting patients’ WHODAS functionality scores per domain achieved a mean absolute percentage error varying between 14.86% and 27.21% among the domains with a set of interpretable features for each domain.

CONCLUSIONS

Our findings show the feasibility of using machine learning-based methods to assess functional health solely from passively sensed mobile data. The feature selection step provides a set of interpretable features for each domain, ensuring better explainability to the models’ decisions.
Assessing the Initial Validity of the PortionSize App to Estimate Dietary Intake Among Adults: Pilot and Feasibility App Validation Study (Preprint)
Authors: Saha Sanjoy , Lozano Chloe Panizza , Broyles Stephanie , Martin Corby K , Apolzan John W
Published: March 2022

BACKGROUND

Accurately assessing dietary intake can promote improved nutrition. The PortionSize app (Pennington Biomedical Research Center) was designed to quantify and provide real-time feedback on the intake of energy, food groups, saturated fat, and added sugar.

OBJECTIVE

This study aimed to assess the preliminary feasibility and validity of estimating food intake via the PortionSize app among adults.

METHODS

A total of 15 adults (aged 18-65 years) were recruited and trained to quantify the food intake from a simulated meal by using PortionSize. Trained personnel prepared 15 simulated meals and covertly weighed (weigh back) the amount of food provided to participants as well as food waste. Equivalence tests (±25% bounds) were performed to compare PortionSize to the weigh back method.

RESULTS

Participants were aged a mean of 28 (SD 12) years, and 11 were female. The mean energy intake estimated with PortionSize was 742.9 (SD 328.2) kcal, and that estimated via weigh back was 659.3 (SD 190.7) kcal (energy intake difference: mean 83.5, SD 287.5 kcal). The methods were not equivalent in estimating energy intake (P=.18), and PortionSize overestimated energy intake by 83.5 kcal (12.7%) at the meal level. Estimates of portion sizes (gram weight; P=.01), total sugar (P=.049), fruit servings (P=.01), and dairy servings (P=.047) from PortionSize were equivalent to those estimated via weigh back. PortionSize was not equivalent to weigh back with regard to estimates for carbohydrate (P=.10), fat (P=.32), vegetable (P=.37), grain (P=.31), and protein servings (P=.87).

CONCLUSIONS

Due to power limitations, the equivalence tests had large equivalence bounds. Though preliminary, the results of this small pilot study warrant the further adaptation, development, and validation of PortionSize as a means to estimate energy intake and provide users with real-time and actionable dietary feedback.
Vulnerabilidades rurales a partir del envejecimiento entre nahuas del sur de Veracruz / Rural vulnerabilities due to aging among the Nahuas in southern Veracruz
Authors: Lazos-Chavero Elena , Jiménez-Moreno Marcela
Published: March 2022

Las vulnerabilidades socioambientales, económicas y culturales del campo mexicano se expresan a través de las transformaciones generacionales y territoriales que minan los ámbitos agroambientales y alimentarios. El envejecimiento rural ha llevado a la venta de parcelas, migración juvenil, pérdida de agrobiodiversidad y transformaciones de los conocimientos agroecológicos que caracterizaban a los pueblos indígenas y campesinos. El objetivo de este artículo es analizar las consecuencias socioambientales y territoriales del envejecimiento rural en la sierra de Santa Marta, expresadas en la venta de sus tierras y pérdida de cultivos, lo que ha llevado al empobrecimiento de su seguridad alimentaria. En julio 2019, se levantaron 59 entrevistas en el ejido nahua de Tatahuicapan de Juárez con el fin de analizar las amenazas a la sustentabilidad y bienestar social en el sur de Veracruz.Abstract: The socio-environmental, economic and cultural vulnerabilities of rural Mexico are expressed through the generational and territorial transformations that undermine the agro-environmental foodscapes. Rural aging has led to the sale of family plots, youth migration, loss of agrobiodiversity and transformations of agro-ecological knowledge that characterized the peasantry and indigenous people. The aim of this paper is to analyze the socio-environmental and territorial consequences of rural aging in the Sierra de Santa Marta, expressed in the sale of land and the loss of crops, which has led to the impoverishment of their food security. In July 2019, 59 interviews were held in the ejido of Tatahuicapan de Juárez, of Nahua origin, in order to analyze the threats to sustainability and social well-being in the region.Keywords: rural aging; youth migration; agricultural succession; loss of agrobiodiversity; food security. Résumé : Les vulnérabilités socio-environnementales, économiques et culturelles du milieu rural se développent suite aux transformations générationnelles et territoriales qui ont affecté les espaces agroalimentaires et de l’alimentation. Le vieillissement des agriculteurs a entraîné de profonds changements dans la structure de la propriété, la migration de jeunes, la perte de l’agrodiversité et les transformatios des savoirs qui caracterient les peuples autochtones. Cet article vise à montrer comment le vieillissement des agriculteurs de la Sierra de Santa Marta a conduit à l’appauvrissement de leur sécurité alimentaire. Sur la base de 59 interviews réalisées en juillet 2019 dans l’ejido nahua de Tatahuicapan de Juárez afin d’analyser les menaces à la durabilité et au niveau du bien-être social.Mots-clés : vieillissement rural ; migration des jeunes ; héritage des terres ; perte d’agrodiversité ; sécurité alimentaire.
Retirement Planning: A Pre-Retirement Framework for Employees of Wesleyan University-Philippines
Authors: Castillo Manuel P. , Mamaclay Ali G. , Guevara Melquiades A. , Ayro Eufemia C.
Published: March 2022

This study aims to design a pre-retirement conceptual framework for employees. The framework’s basis is the respondents’ demographic profile such as age, sex, civil status, years of service, educational attainment, nature of work, and monthly salary. The extent of readiness in terms of financial planning, wealth, health, and network engagement. And the challenges in terms of lack of knowledge in Investment, difficulty in time management, poor attitude towards savings, and running out of money. The study respondents were 40 employees who were 55 years old and above, working at Wesleyan University – Philippines, Cushman campus. The study made use of a descriptive research design. The instrument was a survey questionnaire created by the researchers and was critiqued and validated by a panel of experts in terms of its content. It was piloted to a group of teachers before it was used. The demographic profiles were presented according to percentages, and weighted means for the extent of readiness were used.The respondents were mostly faculty, female, married, and 57-58 years. They have been working for almost 20-29 years in the institution with the highest educational attainment of a master’s degree and have a current salary range of P24,600.00 – P28,600.00. Regarding the extent of readiness for retirement, the employee respondents still need more income for a longer time to save and invest accordingly in terms of financial planning. Also, in terms of wealth, employees’ respondents know how much money they still needed to accumulate by retirement. Moreover, in terms of health, respondents have a regular check-up to reduce healthcare costs make them more aware of their health. The correlation analysis showed that the respondents’ profile variables were significantly correlated with the extent of readiness of WU-P employees towards retirement. Likewise, the respondents’ profile and the challenges faced by WU-P employees towards retirement are significantly correlated. A pre-retirement conceptual framework was designed to focus on aspects of readiness for retirement and some wellness dimensions. It can be concluded that most of the respondents were not ready for retirement. Therefore, a Pre-Retirement Conceptual Framework for employees is designed to prepare respondents for retirement. The study recommended adopting this pre-retirement conceptual framework and using this framework in developing a pre-retirement program for employees. Institutions should financially support the pre-retirement program for employees.
OBSERVACIONES DE DEPREDACIÓN, DIETA Y REPRODUCCIÓN DE Holcosus gaigeae (SQUAMATA: TEIIDAE)
Authors: Nahuat Cervera Pedro Enrique , Pérez-Martínez Luis Roberto
Published: March 2022

Holcosus gaigeae es una lagartija de tamaño pequeño y cuerpo moderadamente robusto que tiene una distribución restringida a la porción Mexicana de la Península de Yucatán. La información existente acerca de su ecología e historia natural es limitada. En este escrito se presentan observaciones de depredación, dieta y reproducción de H. gaigeae en diferentes porciones de los estados de Yucatán y Campeche, en México, las cuales aportan nueva información acerca de los aspectos ecológicos de esta especie.
NEW RECORDS OF THE INTRODUCED SNAKE Indotyphlops braminus (SQUAMATA: TYPHLOPIDAE) IN THE STATE OF VERACRUZ, MEXICO.
Authors: Vásquez-Cruz Víctor , Reynoso-Martínez Arleth , Fuentes-Moreno Axel , Pérez-Gámez Eduardo Michell , Kelly-Hernández Alfonso , Rovito Sean M. , Castillo-Juárez Jorge Luis
Published: March 2022

Indotyphlops braminus is a snake introduced into Mexican territory; it can be found in different republic states. In Veracruz, it has previously been reported from three municipalities. Our observations in the present note provide four new records for the distribution of I. braminus in Veracruz.
LLAMADA DE SOCORRO DE Smilisca baudinii (HYLIDAE) DURANTE LA DEPREDACIÓN POR Leptodeira polysticta (DIPSADIDAE) EN CHIAPAS, MÉXICO
Authors: Mendoza-Henao Angela
Published: March 2022

Leptodeira snakes are frog predators. Here I report the predation of the Mexican treefrog Smilisca baudinii by L. polysticta and I provide quantitative data on the distress call emitted by the treefrog. Besides, I compare some Leptodeira species' prey information based on previous records.
Laser Based Smart Security Apparatus Using Arduino
Authors: Goel Vipul , Varshney Rishabh , Parashar Saksham , Ali Sahil , singh Pravesh
Published: March 2022

Abstract: Our paper deals with the plan and execution of a LASER based smart security system for discovering burglar. The principal edge of using the Laser system is that the burglar is unmindful of the fact that a security system is fix in the entry points like doors and windows since laser rays can travel long distances and are almost imperceptible. When someone go through the laser ray the circuit senses the cutoff and stumble the alarm. The alarming sound does not stop until someone turns it off manually after scrutnizing. It is one of the most economical security apparatus that can be used for indoors as well as outdoors. This apparatus centre of attention is on sending a photo of the burglar into the registered email address for sustainable verification with the help of LDR and WIFI module. It is quite competent and need very minimal power. Important terms: Arduino, LDR module, WIFI module, Piezo buzzer, message alert, laser module security
A Movie Recommender System Using Hybrid Approach: A Review
Authors: Mohile Sara , Ramteke Hemant , Shelgaonkar Pragati , Phule Hritika , Phadtare M. M.
Published: March 2022

Abstract: The topic of this paper is movie suggestions. Because of its ability to provide improved entertainment, a movie recommendation is vital in our social lives. Users can be recommended a set of movies depending on their interests or admiration for the films by such a system. A recommendation system is used to make suggestions for things to buy or see. They employ a big collection of information to steer consumers to the things that will best match their needs. A recommender system, also known as a recommendation system, is a type of material filtering system that attempts to forecast a user's "rating" or "preference" for an item. They're mostly employed for commercial purposes. MOVREC also assists users in efficiently and effectively locating movies of their choice based on the movie experiences of other users, without wasting time in pointless searching. Keywords: Filtering, Recommendation System, Recommender.
The Diplomatic Activity of the Crimean Khanate and Its Economic Consequences in East-Central Europe in the 16th–18th centuries
Authors:   University of Szeged, Ivanics Mária
Published: March 2022

Research objective: The article is devoted to the discussion of the establish­ment and the development of diplomatic relations between the Crimean Khanate and the countries of East-Central Europe, with special attention paid to the political and economic influence of the Khanate in the European vassal states of the Ottoman Empire. Research materials: The study uses European and Ottoman chronicles, reports from Constantinople, and still unpublished documents from the Austrian, Romanian, and Hungarian archives. Results and novelty of the research: Ottoman studies has paid little attention to the diplomatic relations of the Crimean Khanate with East-Central Europe. Historical studies primarily emphasized the auxiliary role of Tatars in the Ottoman campaigns and did not pay attention to the fact that in their shadow the khans established and maintained diplomatic relations with the sovereign and vassal states of the region. After thorough research in the archives of the region, it was possible to compile a corpus of documents which revealed the process of the development of the khanate’s diplomatic relations, sometimes even leading to cooperation between the Muslim and Christian rulers. The analysis of the collected and systematized material made it possible to establish the role the khanate played in the policy of the Christian vassals of the Porte, and also the development of the taxation of vassal countries by the Tatars. In the case of Moldova and Wallachia, the sources made it possible to trace the formation of different types of obligations and the amount of tribute.