bluuebunny/crossref_metadata_2025 huggingface dataset:
Reflections on the Interconnectedness of Narrative Strategies and Identity Crisis in Anita Nair’s Ladies Coupe
Authors: - N. Shajitha  Parveen
Published: January 2024

Women experience subjugation, suppression, discrimination, and marginalization within patriarchal societies. Anita Nair's literary works explore the varied roles that women assume in their everyday existence and their challenges in the process of self-exploration. Anita Nair's first novel, Ladies Coupe, explores the protagonist's psychology and examines the suppression of women's identity in Indian society through her storytelling technique. To address the unfortunate situation of women, Nair briefly focuses on the condition of contemporary women in a culture dominated by men and their suffering due to the institution of marriage. The objective of this article is to examine the narrative tactics and strategies utilized in the novel Ladies Coupe. Nair's narration serves as a critique of gender norms and the subjugation of women inside a patriarchal culture. She focused her plot narration strategies on depicting women as independent, strong, and outspoken which reflects her changed role from the traditional norm. This paper tries to explore the different narrative techniques subtly interwoven into the texture and structure of her novel Ladies Coupe.
Assessing the Medico-legal Knowledge of Health Care Professionals: The Case of Konongo Odumasi Government Hospital
Authors: - Gideon Danso
Published: January 2024

Introduction: There is growing public awareness regarding the ethical conduct of medical practitioners. Hence knowledge about medico-legal issues is as important to the practice of medicine as clinical skills.

Method: A survey was conducted among some health care professionals at Konongo Odumasi Government Hospital, Ghana. A self-administered questionnaire was used to elicit information on informed consent, confidentiality and medico-legal issues. Data collected was analysed using SPSS version 20.

Results: A total of 100 health care workers were enrolled on the study representing 100% response rate. The study revealed that 96% had knowledge or were aware of medico-legal issues; and 26% of the respondents indicated that disclosing a patient's medical information to someone else cannot lead to a medico-legal case. About 28% of the health care professionals had inadequate knowledge on physician-assisted suicide. 89% of the respondents indicated that taking precautions is very good as it can prevent a charge of malpractice and 80% of the health care professionals indicated that lacking medico-legal knowledge can affect you in your profession.

Conclusion: Knowledge of health care professionals on informed consent, confidentiality and medico-legal issues is high and their perceptions are positive. However, regular training to update their knowledge will be necessary in order to ensure continuous improvement of the quality of health care delivery.
Performance of Students of Arts & Science Colleges and Engineering Colleges - A Comparative Study with Special Reference to Virudhunagar District
Authors: - Dr.A. CHELLA DURAI , - Dr.R.C. SARAVANA KUMAR
Published: January 2024

The goal of the current study is to evaluate employability and academic performance among college students majoring in science, engineering, and the arts, and to look into the relationship between the two. Sixty college students from Tamil Nadu Virudhunagar area made up the sample. The percentage, average, means, S.D., t-test, and ANOVA tests were used to analyse the data. To demonstrate the sample students' level of academic performance, the examination's total score (%) was calculated. The findings showed a substantial difference in the academic performance of graduates in engineering and arts and sciences. Future studies should use self-motivation measures to more fully understand the impact of ethnicity on study effort and academic performance in college.
Marital Adjustment and Emotional Empathy in Married Couples
Authors: - Aarti Jain
Published: January 2024

Marital adjustment is the state in which there is feeling of happiness and satisfaction between husband and wife with their marriage and with each other. Marital adjustment refers to a process and outcome which is determined by the amount of differences, interpersonal tensions and personal anxiety, satisfaction, cohesion and consensus and affection expression in marital relationship. Emotional empathy refers to one's vicarious experience of another's emotional experiences and feeling what the other person feels. The present study adopts a between groups design to study the difference between married couples living in same city and married couples living in different cities with respect to marital adjustment and its dimensions and emotional empathy. The study also adopts between group design to study gender difference among the married couples living in same city and married couples living in different cities. Furthermore, the study adopts correlational design to determine the relationship between marital adjustment and emotional empathy among married couples living in same city and married couples living in different cities. Non-probability purposive sampling was used to select a sample of married couples living in same city (N=50) and married couples living in different cities (N=50). Results showed that there were significant differences between married couples living in same city and married couples living in different cities with respect to the satisfaction, consensus, cohesion and affection expression dimensions of marital adjustment and emotional empathy. Significant differences were also found between men and women with respect to the satisfaction and consensus dimensions of marital adjustment and emotional empathy. The study recommends that support and understanding from spouses and better affection expression would help married couples achieve greater marital satisfaction.
Land Surface Temperature and Urban Heat Island: A Case Study of Faridabad City using RS and GIS techniques
Authors: - Abhishek Malik , - Gaurav Kalotra
Published: January 2024

Land use and land surface temperature both plays a crucial role in the global climate change studies, as a little fluctuation in these, can bring about a dramatic impact on the regional as well as global environment. With rapid urbanization many regions across the world are altering the existing land use/land cover (LULC), which is significantly raising the land surface temperature (LST). The present study aims to estimate the land use change and land surface temperature and what changes does both bring about in a span of 20 years over Faridabad MC. Faridabad being a part of Delhi NCR has seen rapid growth of population in last two decades which has severely impacted its Land cover. Landsat imagery of 2002, 2013 and 2022 has been used for estimating both the LULC and LST of the city. Supervised classification with Maximum likelihood Classification (MLC) which is basically a machine learning based algorithm has been adopted for LULC classification and Mono window algorithm has been used for the retrieval of LST. UTFVI (Urban Thermal Field Variance Index) has also been calculated which showed different Urban heat islands across the city. The results reveal a rapid increase in the built-up area and reduction in the vegetation and agricultural land. Similarly, Land surface temperature was highest in highly dense built-up areas as well in the barren area of Faridabad, compared to this LST was comparatively lower over the agriculture and vegetation and least of water bodies. There were several UHI hotspots over the city area, mostly located in the densely populated and industrial parts of city.
Dew Water of Tamarisk Leafs (Salt Cedar) for Treating Warts Infection in Libya
Authors: - Khalifa A A Fatnasa
Published: January 2024

Warts are caused by Human papiloma virus which causes a skin infection in all ages, it is un-convenient, if not treated by using the relevant medicine. Tamarisk is a plant commonly known as Salt cedar or, (Athal in Arabic region), which belongs to the Tamaricaece species, the presence of high content of phytochemical compounds like polyphenolics and flavonoids, is a potential source of antioxidant, anti-inflammatory and antiproliferative properties, that seems to have secrete medication effect on warts infection. A study to dew water of tamarisk leafs effect on warts infection have showed magic results, seven cases used dew water as remedy irregularly once per day for four to seven times per month, all cases totally healed from warts infection and responded positively 100% to the use of tamarisk leafs dew water.
3D Printing in Pharmaceutical Technology as a Promising Tool for the Design and Manufacture of Pharmaceutical Oral Formulation - A Review
Authors: - Vaidehi Sunil Holey , - Prof. Shailesh G. Jawarkar , - Prof. Ajay W. Baitule
Published: January 2024

By applying material to a substrate, three-dimensional printing is a cutting-edge process that creates three-dimensional things using computer-aided design software and programming. A three-dimensional structure is created by depositing or solidifying successive layers of material in a process known as additive layer manufacturing, or 3D printing. Using a computer-aided design module, medicinal chemicals are designed in three dimensions and converted into a machine-readable form that indicates the outer emergence of the three-dimensional dosage form. This surface is then divided into several printable coats, which are subsequently sent to the machine. Various 3D printing methods have been developed over time to create innovative solid dosage forms, which are some of the most well-known and distinct items available today. The pharmaceutical industry wants to support 3D printing technology and explore the amazing things that can be accomplished with it. Using 3D printing opens up a world of new possibilities for improved medical care.
Now that the FDA has approved Spritam, the first 3D-printed tablet, there is precedent for using 3D printing to prepare medication delivery systems. The ability to precisely manage the spatial distribution, precisely dispense small quantities, and assemble layers upon layers facilitates the creation of intricate compositions and geometries. The creation of dosage forms including several active medicinal components with complex and customized release profiles is made possible by the high degree of flexibility and control that comes with 3D printing. A special chance for this technology to prepare customized doses to meet the demands of each particular patient.
Examining Cross-Border Insolvency: Global Challenges and Collaborative Solutions.
Authors: - VICTORIA THAKUR , - SIDDHARTH KESWANI
Published: January 2024

The background of this research underscores the critical need for a more cohesive and streamlined approach to cross-border insolvency. By understanding the global challenges and exploring collaborative solutions, the research aims to contribute valuable insights to the academic, legal, and policy discourse surrounding the evolving dynamics of insolvency in an interconnected world. Ultimately, the goal is to provide a foundation for improving international cooperation and legal frameworks to address the complexities posed by cross-border insolvency cases.
A Study on Exclusive Brand’s Marketing Optimization
Authors: - Bhagyalakshmi G , - Suriyanarayanan G S
Published: January 2024

This research walk-through the various methods used by exclusive and upscaled organizations that minimized its marketing Champaign and budgeting. Generally, posh products and service are not marketed through Integrated channels that are commonly available. As these companies differentiate themselves through unique innovative features they opt for specific single streamed path for marketing that directly reach-out its targeted customer group than spending on popularity promotions. In further discussions exclusive brand is categorized into known and Un-known,
• Known Brands: Posh and exclusive brands that has a brand image among common customer base and spend on brand awareness and popularity promotion, such as Apple and Tesla.
• Unknown Brands: Completely exclusive service or product which does not focus on brand awareness and also ensure they do not exist in common market, but strategically sustain stronger among its targeted customer segment.
Study includes a market research analysis about the brand awareness and customer’s perceived knowledge about exclusive brands along their products and service that facilitate for its premium pricing.
A Study on Bus Passengers Behaviour with Special Reference to Bangalore City
Authors: - D SRINIVASULU , - R NADIYA
Published: January 2024

The transport system provides the basic infrastructure and it affects the economic activities of the country. The transport sector in India is divided into passenger and freight. The passenger services are available in both government private of bus category. At present private sector owns majority of the buses compared to government. In Andhra Pradesh and Karnataka also the private transport players dominating the passenger’s transportation market, especially if the travelling distance is more than 250 KM. Initially consumers (passengers) have been attracted with the facilities and service given by private bus operators. With the increasing competition and other policy issues, the private bus operators are implementing peak load pricing strategy.
This pricing strategy is unexpected and unjustifiable to any passenger and even unbearable to them. And the facilities and service are same. Therefore a study has been made by the researcher to bring out the passengers behavior with peak load pricing by private operators with reference to Bangalore city in the state of Karnataka . By using judgment random sampling technique, 110 respondents were selected as sample size and information gathered through interview method. The outcome of the research has shown very interesting results such as customers’ dissatisfaction on Government failure to control the Private Bus operators and the price exploitation, in connection with their no alternative to avoid the services
A Comparative Study of Educational Aspiration among Scheduled Caste Secondary School Students
Authors: - Kewal Krishan , - Shamboo Nath , - Bushan Kumar
Published: January 2024

The present study has an attempt to explore levels educational aspirations of scheduled caste secondary school students. To study and compare the levels of educational aspiration of scheduled caste secondary school students. A representative sample of 760 form class 9th and 10th class students was randomly selected from government schools. Tools for collecting the data included Educational Aspiration Scale developed by Yashmin Ghani Khan, (2019). The data were analysed using descriptive statistics and T-Test, the finding of the study revealed majority of scheduled caste secondary school students fall under Average Realistic levels of Educational Aspiration and also found that the majority of scheduled caste secondary school students fall under Average Realistic levels of Educational Aspiration both gender male and female respectively. Moreover, data depicts that there is no significant difference between male and female scheduled caste secondary school student on educational aspiration levels.
लुवीस मस्करेनस हाणी बरयलेल्या आब्रांवचे यज्ञदान काव्यनाटकाचेर साहितीक नियाळ
Authors: - Wilma Fernandes , - Dr. Arvind Chandrakant Shanbhag
Published: January 2024

लुवीस मस्करेनस हाणी बरयलेल्या आब्रांवचे यज्ञदान काव्यनाटकाचेर साहितीक नियाळ
केंद्र साहित्य अकाडेमी पुरस्कार लाभलेल्या करावळी कर्नाटक कविता संग्रहांचे विश्लेषणात्मक अध्ययन
Authors: - Wilma Fernandes , - Dr. Arvind Chandrakant Shanbhag
Published: January 2024

कविता म्हळ्यार कितें? हें सवाल हरयेकल्या वाचप्याच्या मतींत येंवचे सहज. पुण
ह्या सवालाक जोकती जाप मेळाना कित्याक म्हळ्यार कवितेचीं व्याख्यांनांचेर नदर घाल्यार
वेवेगळे विचार आमकां दिसोन येतात. तयार करून बरंवचें, तें कविता जायना, खंचाय घडिये
आपापिंच मनांत उदेंवच्या उतरांक रूप दिताना कविता घडता. कविता साहित्याचो उंचलो प्रकार
जावन आसा. कोंकणी कवितेची सुर्वात एकुणिसाव्या शेकड्याच्या अकरेक सुरु जाली.
सुरविल्ल्या वर्सांनी धार्मिक तशेंच अनुवादित कवितांचे योगदान कोंकणी भाशेक लाभल्या
उपरांत सवकास करनाटकांत श्री लुवीस मस्करेनस मारिफात खरे कोंकणी कवितेचो उदेव
जालो म्हणोन आमी वाचोन आनी आयकोन आयल्यांव. ह्या अध्ययनांत हांवे केंद्र साहित्य
अकाडेमी पुरस्कार लाभलेल्या कारावळी कर्नाटक कविता संग्रहाचे विश्लेषणात्मक अध्ययन
करुंक चिंतलां. हो विषय हांवे घेतलो कित्याक म्हळ्यार कविता, कोंकणी साहित्याचो प्रमुख
वांटो जावन आसा तरी ह्या दिशेन संशोधनात्मक अध्ययन जाल्लेले दिसोन येना.
Effects of Cognitive Sensory Motor Training Versus Repetitive Facilitation Exercises of Upper Limb in Hemiparetic Patients
Authors: - KARTIK CHHONKER , - NAMRATA SRIVASTAVA , - KALPANA JAIN , - GUNJAN SHUKLA
Published: January 2024

Stroke [CVA] is the sudden loss of neurological function caused by an interruption of blood flow to the brain. Large numbers of people who survive a stroke are left with permanent impairment of arm and hand function, even after completion of conventional rehabilitation programs. The standard neuro physiological facilitation technique use for hemiplegic upper limb have not been confirmed to promote functional recovery of hemiplegic limb. This promote that more research needs to be conducted for same.
Cognitive Sensory Motor Training Therapy & The repetitive facilitation exercises (RFEs) Both techniques will promote functional recovery of hemiparetic upper limb and hand by improving joint perception and realization of movement. Hence, this study aims to compare the effectiveness of cognitive sensory motor training versus repetitive facilitation exercises on quality of movement of upper limb, functional activity and Range of motion of upper limb in hemiparetic patients.
A blinded randomized clinical trial was conducted 30 patients were divided into 2 groups (GROUP A and GROUP B)- those who performed cognitive Sensory Motor exercises(GROUP A- experimental group) and those who performed repetitive facilitation exercises (GROUP B-control group) Data for measures quality of movement performance of the hemiparetic arm and hand on MESUPES scale, Barthel Index (BI) measures the extent to which somebody

can function independently and has mobility in their &, goniometer measuring the joint ranges in each plane of the joint was collected on day 1 (pretreatment session), and on 190 day after the experiment.
This study produced a stastically significant increase in overall on quality of movement, functional activity and range of motion in both the group of upper limb in hemiplegic patients. This research also provides evidence that training exercise may be a valuable and important tool in clinical practice and is consistent with the current use by clinical physiotherapist in the treatment of upper limb in hemiplegic patients.
Watershed Management for Sustainable Livelihoods: Integrating Local Pond Ecosystems in Malda, West Bengal
Authors: - Md. Moazzam Hossain , - Kamal Kant Patra
Published: January 2024

This research article explores the intricate relationship between watershed management, local pond ecosystems, and sustainable livelihoods in the Malda district of West Bengal. The study investigates the potential of integrating local pond ecosystems into watershed management strategies as a means to enhance economic prosperity, ecological resilience, and community well-being. Through a multidisciplinary approach, combining ecological assessments, socioeconomic surveys, and participatory engagement, the research aims to provide insights into the synergies that exist between watershed management practices and the sustainable livelihoods of the local villagers.
The research methodology involves field studies encompassing hydrological analysis, biodiversity assessments, and community consultations, aimed at understanding the dynamics of local pond ecosystems and their interconnectedness with the broader watershed. Special attention is given to the diverse ecosystem services provided by these ponds, such as water provisioning, nutrient cycling, and supporting aquatic biodiversity, and how they contribute to the overall resilience of the watershed.
The findings of this study are expected to contribute valuable information for policymakers, environmental practitioners, and local communities in Malda district, offering a comprehensive understanding of how the integration of local pond ecosystems into watershed management plans can foster sustainable livelihoods. The article discusses potential strategies for optimizing the co-management of these resources, balancing the ecological health of the ponds with the socioeconomic needs of the local population.
Ultimately, this research aims to provide a blueprint for sustainable watershed management practices that prioritize the conservation and utilization of local pond ecosystems, fostering a harmonious balance between ecological integrity and the livelihood aspirations of the communities in Malda, West Bengal.
Exploring the State of Indian Politics During Partition
Authors: - Aadya Sinha
Published: January 2024

The study investigates the state of Indian politics during the partition, with a focus on the role of key political figures, the impact of political parties, and the communal violence that ensued. The methodology involves a systematic review approach as well as first-hand accounts. The study sheds light on the complex interplay of political forces and communal tensions during this tumultuous period. The key conclusion drawn from this study is that the actions of political leaders and parties heavily influenced the course of events during the partition, contributing to the widespread communal violence that tragically unfolded.
Generative AI: Evolution and its Future
Authors: - Chalamayya Batchu , - Veera Venkt Satya
Published: January 2024

Generative AI (Gen AI) is an emerging AI Technology which broadly describes machine learning systems capable of generating numerous applications in various domains. AI Users can use Gen AI for generating text, image, program code or other types of contents. The main capability of Gen AI is to produce highly realistic and complex contents that can imitate human creativity, making a valuable AI for many application domains. This paper focuses on emergence, its evolution and future of Generative AI.
Cultural Responsive Teaching: Increasing Student PPKn Learning Outcomes
Authors: Latipia Damayanti  , Hiltrimartin Cecil , Wati Destiana
Published: January 2024

Purpose of the study: This research will explore how a culturally responsive teaching approach can improve students' cognitive learning outcomes. This classroom action research aims to enhance students' cognitive learning outcomes using a culturally responsive teaching approach.
Methodology: This research was carried out in class III in Civics subjects. The type of research method used by researchers was Classroom Action Research. The population and sample used in this study were all class III students at Elementary School 07 Palembang. Data collection techniques used by researchers are observation, field notes, and tests. Data analysis techniques used are qualitative analysis and quantitative analysis.
Main Findings: The results of this research are that the application of the culturally responsive teaching approach to Civics subjects in class III can improve student learning outcomes with results in cycle I as much as 57.6%, cycle II as much as 73%, and cycle III as much as 88.4% and post-test 92%. .3% with a student completion target of 85%.
Novelty/Originality of this study: Researchers used a culturally responsive teaching approach to improve students' cognitive learning outcomes in grade III Elementary School Civics subjects.
The Impact of Unidentified Elementary School Students' Character Values in the Independent Curriculum Class IV Science Science Teacher's Book
Authors: Yusnidar Yusnidar
Published: January 2024

Purpose of the study: This study aims to analyze the impact of student character values that have not been identified as Independent Curriculum Class IV Science Teacher's Book.

Methodology: The method used is qualitative. Researchers use a document study instrument to collect the required literature, such as soft books/hard books, and others. The sample used in this study was class IV science subjects in the Independent Curriculum teacher's book.

Main Findings: This study shows that in class IV, several character values are not found in students. This is because the teaching and learning process is not directed at these character values. This hurts students, affecting the learning process in class and when students are in their environment.

Novelty/Originality of this study: The latest from this study is to analyze the character value of students in elementary schools in aspects of the independent curriculum.
Efforts to Improve Science Learning Outcomes Through the Problem-Based Learning Model for Students in Bengkulu
Authors: Sukarno Sukarno
Published: January 2024

Purpose of the study: This research aims to address the low student learning outcomes in the science learning subjects of class IV elementary school students in Bengkulu by applying the Problem Based Learning model and examining its effectiveness in enhancing the student learning outcome.

Methodology: The research uses a Classroom Action Research method with two cycles, each consisting of planning, implementation, evaluation and reflection stages. The research subjects are 20 students in class IV Elementary School in Bengkulu. The data collection technique is a test.

Main Findings: The research data shows that the Problem Based Learning model can improve the learning outcomes of class IV elementary school students in Bengkulu. The completeness of learning outcomes increases from 3% in the pre-cycle to 65% in the first cycle and 85% in the second cycle, exceeding the expected outcome of 75%.

Novelty/Originality of this study: The novelty in this research is the application of the Problem Based Learning model in the science learning subjects of class IV elementary school students in Bengkulu, which have different characteristics and needs from other students in other regions or countries. The research also contributes to the development of the Classroom Action Research method, which involves the active participation of the teacher and the students in the learning process and the improvement of the learning quality. The research has implications for the improvement of the science curriculum and the teacher training program in Bengkulu.
Analysis of The Influence of Institutional Ownership, Managerial Ownership, and Ownership Structure on Company Financial Performance: Case Study of Manufacturing Companies In Indonesia
Authors: Effendi Syahril , Prima Argo Putra
Published: January 2024

This research aims to analyze the impact of institutional ownership, managerial ownership, and ownership structure on the financial performance of manufacturing companies in Indonesia. Financial performance is measured using various indicators such as profitability, liquidity, and leverage. The study is based on data from a number of manufacturing companies in Indonesia during the period 2020-2022. The results of the analysis indicate that institutional ownership has a significant positive impact on the financial performance of companies, suggesting that the presence of institutional shareholders can enhance efficiency and profitability. On the other hand, managerial ownership also contributes positively to financial performance, indicating that active management participation in share ownership can drive growth and profitability. However, the research findings show that the impact of ownership structure varies depending on the financial performance indicators considered. There are significant differences in the influence of ownership structure on profitability, liquidity, and leverage of the companies. This research provides valuable insights for stakeholders, regulators, and company owners in understanding the role of institutional ownership, managerial ownership, and ownership structure in enhancing the financial performance of manufacturing companies in Indonesia. The practical implications of these findings can help companies in making better decisions regarding share ownership and financial strategies.
الجذور العرقية للإغريق وتشكل الأمة الأغريقية
Authors: محمد احمادي د.الطيب
Published: January 2024

تعرره الررر ااجذور ذررياجذتررر لإغاجق،هحسبررياذفيررروبياجل،هحرر ا يررر ا ررر لإغ ا ررر اجذو ررر غاجذف غح برررياجذوهفورررريا، ذوث ررررثم ا وررررلاترررر طهاجذفيرررروبيالإ رررر ه الإجذو رررر اجذوهت رررريا،رررر الإ عرررر اجذ ررررب اجذوع هةاذف كاجذفيوبي.
الجبل الأخضر دراسة في التنمية السياحية
Authors: أحمد الجهمي د.كريمة
Published: January 2024

تهدف هذه الد ا رسة إلى تسليط الضوء على المقومات الطبيعية والبشرية السياحية بالجبل الأخضر؛ أيعناصر الجذب السياحي: الطبيعي، والتاريخي، والأثري، والثقافي، ومدى توافر البنية الأساسية لقيام نشاطسياحي، ومدى توافر الفنادق، والمطاعم، والخدمات السياحية المختلفة، ومن ثم تقييم هذه الإمكانات؛ حتىيتسنى لنا الوقوف على أهم المعوقات التي تقف أمام النشاط السياحي بالبلاد ، ومحاولة تنميتها بوضع بعضالمقترحات التي تعمل على تذليل هذه المعوقات، حيث يتمتع الجبل الأخضر بعناصر جذب سياحي عديدة،تتمثل في عناصر الجذب الطبيعية في: الموقع الجغ ا رفي، وشكل سطح الأرض، والشواطئ، والجبال، والغابات،والمناخ ال ا رئع المعتدل، والنبات الطبيعي، والحياة الحي وانية بصفة عامة، وهو غني بعناصر الجذب البشريةالتي تشتمل على: التاريخ، والآثار، والثقافة، والفنون، والم ا رفق السياحية، وغيرها.
اضطراب التواصل اللُّغوي لدى عينة من أطفال التوحد كما يدركه القائمون بالرعاية في مدينة بنغازي
Authors: الحضيري د.سعدة احمد , عبدالعاطي د.نزيهة سليمان
Published: January 2024

تهدف هذه الدراسة إلى معرفة مستوى الاتصال اللغوي، ومعرفة مستوى كل بعد من أبعاد الاتصال اللغوي المتمثلة في: مهارة التقليد، الانتباه، الفهم والتعرف، التعبير، والتسمية عند أطفال التوحد، كما تسعى إلى معرفة الفرق في مستوى الاتصال اللغوي بين أطفال التوحد الملتحقين بالمراكز التأهيلية العامة والخاصة في مدينة بنغازي. وقد طبقت هذه الدراسة على عينة مقصودة من أطفال التوحد، الذين تراوحت أعمارهم من (14:6) سنة، وبلغ عددهم (50) بواقع (25) طفلا، من كل مركز لتأهيل أطفال التوحد، ولتحقيق أهداف الدراسة استخدمت استمارة البيانات الأولية، التي تحتوي على بيانات أولية عن الطفل. وكذلك استخدم مقياس تقدير الاتصال اللغوي لدى أطفال التوحد من إعداد (نصر، 2002) للتعرف على مظاهر الاتصال اللغوي ومستواه، عند حالات التوحد، ويشتمل المقياس على (50) موقفا موزعا على خمسة أبعاد لغوية، كل بعد يمثل مهارة من مهارات الاتصال اللغوي وهي التقليد، الانتباه، الفهم والتعرف، التعبير، التسمية. وقد استخرجت البيانات السيكومترية للمقياس بطرق عدة؛ للتأكد من صلاحية استخدامه على البيئة الليبية. وتبين من نتائج الدراسة أن ما يقارب نصف أفراد العينة لديهم مستويات متوسطة فأقل من التواصل اللغوي تقدر بحوالي (46 %)، كما أظهرت النتائج أن الاتصال اللغوي المرتفع، والمرتفع تماما كان لصالح المركز الليبي التخصصي لتأهيل أطفال التوحد (الخاص)؛ حيث بلغت نسبة مستوى الاتصال اللغوي (72%).  وكانت مهارة التقليد أعلى مهارات التواصل اللغوي عند أطفال التوحد، بينما مهارة الفهم والتعرف، والتسمية كانت الأقل. وبناء على نتائج الدراسة أوصت بتفعيل برامج التدريب؛ لرفع مهارات التواصل اللغوي عند أطفال التوحد، وبخاصة مهارتي الفهم والتعرف، والتسمية، مع تدريب الآباء والأمهات ودمجهم في البرامج التدريبية المستهدفة؛ لتحسين المستوى اللغوي لأطفال التوحد.
Power Quality Improvement on 11kV/440V Distribution System using DSTATCOM
Authors: Reddy S. R. , Prasad P. V. , Srinivas G. N.
Published: January 2024

At the PCC and source side, current and voltage harmonics are compensated by utilizing a distribution static compensator. In this work, we also compensated for voltage control and reactive power correction. An improved reference current switching signal is suggested using a synchronous reference frame control technique. The analysis is done on an 11kV/440V three-phase four-wire unbalanced nonlinear load distribution system. The DC link voltage and harmonic reduction of the suggested distribution system performance is compared with the PI and fuzzy logic controllers. Harmonic distortion is reduced, and reactive power is successfully compensated with the suggested method. These simulation results are obtained by MATLAB/SIMULINK software.
Antibiofilm Activity of Fukoidans Isolated from Brown Algae
Authors: Matosova E. V. , Besednova N. N. , Kusaikin M. I. , Andryukov B. G. , Makarenkova I. D. , Shchelkanov M. Yu. , Lyapun I. N. , Bynina M. P. , Ermakova S. P. , Zvyagintseva T. N.
Published: January 2024

Biofilms play a significant role in the existence of bacteria under adverse conditions and the pathogenesis of infections. They contribute to the creation of reservoirs of antibiotic-resistant pathogens. This determines the relevance of the search for biologically active substances that inhibit the formation of biofilms. In recent years, the objects of intensive study are fucoidans — sulfated polysaccharides from marine brown algae, which have a wide polyfunctional spectrum of action. Their influence on the formation of Yersinia pseudotuberculosis biofilm in a dynamic model simulating the natural conditions of ecosystems of fucoidans belonging to different structural groups was investigated in this study. They are synthesized by brown algae: Fucus evanescens, Saccharina cichorioides, and Saccharina japonica. The fucoidan isolated from F.evanescens have showed the most pronounced antibiotic activity. The authors developed a new approach that allows obtaining stable results of multidirectional action of sulfated polysaccharides on the biofilm formation of Y.pseudotuberculosis.
Could mycophenolate mofetil combined with benazapril delay tubulointerstitial fibrosis in 5/6 nephrectomized rats?
Authors: LIU Wen-hu , TANG Ni-na , ZHANG Qi-dong
Published: January 2024

Background

It was reported that combination of mycophenolate mofetil (MMF) and enalapril could reduce proteinuria, improve renal function, and down-regulate diabetes-induced macrophage recruitment and expression of monocyte chemotactic protein 1 (MCP-1) and transforming growth factor β (TGF-β) in diabetic renal tissue. But there are no compelling data available for the combination of MMF and angiotensin converting enzyme inhibitor (ACEI) for suppressing tubulointerstitial fibrosis in chronic kidney diseases. The present study was to disclose the effect of MMF combined with benazapril on delaying tubulointerstitial fibrosis and its possible mechanisms in 5/6 nephrectomized rats.

Methods

Fifty male SD rats underwent 5/6 nephrectomy (5/6 NX) were randomized into the following groups: NX (5/6 nephrectomized rats, distilled water, n=10), MMF (MMF 20 mg·kg-1·d-1, p.o., n=10), Ben (benazepril 10 mg·kg-1·d-1, p.o., n=10), MMF/Ben (MMF 20 mg·kg-1·d-1, p.o., and benazapril 10 mg·kg-1·d-1, p.o., n=10). They were monitored for proteinuria and systolic blood pressure every two weeks. After 8 weeks of treatment, serum creatinine and blood urea nitrogen were assayed and pathological damage to the kidney were evaluated. Renal expression and serum levels of platelet-derived growth factor-BB (PDGF-BB), matrix metalloproteinase-9 (MMP-9), and tissue inhibitor of metaloproteinase-1 (TIMP-1) were detected by immunohistochemistry and ELISA methods.

Results

After 8 weeks of treatment, 24-hour proteinuria, serum creatinine and blood urea nitrogen were significantly lower in treated groups compared with the untreated rats. MMF and benazepril combination therapy had a greater effect than either drug alone. MMF alone had no effect on systolic blood pressure, but benazapril and MMF/benazapril could significantly reduce blood pressure. Rats that underwent 5/6 nephrectomy had greater tubulointerstitial inflammatory cell infiltration and collagen accumulation than sham-operated rats; all treatments, especially MMF/benazepril, ameliorated these effects. Tubules in 5/6 nephrectomized rats expressed higher levels of PDGF-BB and TIMP-1 and lower MMP-9 compared with sham-operated rats. MMF and benazepril similarly reversed these phenomenons and combination therapy almost completely restored the expression of these cytokines in renal tissue and their plasma concentration.

Conclusions

MMF, especially combined with benazepril, can reduce proteinuria, improve renal function, ameliorate tubulointerstitial fibrosis in 5/6 nephrectomized rats. These effects might be, in part, associated with down-regulation of PDGF-BB and TIMP-1, and MMP-9 up-regulation in renal tissues.
Clinical analysis and follow-up study of chronic active Epstein-Barr virus infection in 53 pediatric cases
Authors: LU Gen , XIE Zheng-de , ZHAO Shun-ying , YE Ling-jun , WU Run-hui , LIU Chun-yan , YANG Shuang , JIN Ying-kang , SHEN Kun-ling
Published: January 2024

Background

Chronic active Epstein-Barr virus infection (CAEBV) has been previously reported to be sometimes associated with an aggressive clinical course. The characteristics of CAEBV in Mainland Chinese pediatric patients are largely unreported. The main aims of this survey were to recognize the clinical features of CAEBV in children and to explore its diagnostic criteria and risk factors.

Methods

A retrospective study was performed on 53 pediatric patients (36 boys and 17 girls) with CAEBV who were admitted to Beijing Children’s Hospital between 2003 and 2007. All their medical records were reviewed and analyzed. For each patient, demographic, clinical, laboratory data and outcome were collected. Independent-samples t test was used for statistical analysis.

Results

The age at onset of CAEBV was from 2 months to 14.6 years (mean (5.3±3.3) years). At the time of onset, 43.4% patients had an infectious mononucleosis-like symptom. Most patients exhibited intermittent fever (92.5%, 49/53), hepatomegaly (81.1%, 43/53) and splenomegaly (77.4%, 41/53). Life-threatening complications including hemophagocytic syndrome (24.5%, 13/53), interstitial pneumonia (24.5%, 13/53), hepatic failure (15.1%, 8/53) and malignant lymphoma (11.3%, 6/53) were also observed. The serum EBV DNA level in 23 patients with CAEBV was in the range of 5.05×102-4.60×106 copies/ml with a mean value of 103.7 copies/ml. Many patients with CAEBV generally had continuous symptoms during the observational period. Eleven out of 42 patients (26.2%) died 7 months to 3 years after onset. Deceased patients were more likely to have had lower platelet counts and albumin levels than the living patients (P <0.05 for all comparisons).

Conclusions

The study reveals that CAEBV in Chinese pediatric patients has a severe clinical course and prognosis is poor. Thrombocytopenia and decreases in albumin might potentially be risk factors for a poor prognosis. EBV loads should be measured and tissue should be stained on hybridization probes for EBV-encoded small RNA (EBER) if a patient presents with the known symptoms of CAEBV.
Picture perception in Chinese dyslexic children: an eye-movement study
Authors: LI Xiu-hong , JING Jin , ZOU Xiao-bing , HUANG Xu , JIN Yu , WANG Qing-xiong , CHEN Xue-bin , YANG Bin-rang , YANG Si-yuan
Published: January 2024

Background

Currently, whether or not there is visuospatial impairments in Chinese dyslexic children is still a matter of discussion. The relatively recent application of an eye-tracking paradigm may offer an opportunity to address this issue. In China, in comparison with reading studies, there have not been nearly as many eye movement studies dealing with nonreading tasks such as picture identification and whether Chinese children with dyslexia have a picture processing deficit is not clear. The purposes of the present study were to determine whether or not there is visuospatial impairments in Chinese dyslexic children. Moreover, we attempted to discuss whether or not the abnormal eye movement pattern that dyslexic subjects show during reading of text appropriate for their age is a consequence of their linguistic difficulties.

Methods

An eye-link II High-Speed Eye Tracker was used to track the series of eye-movement of 19 Chinese dyslexic children and 19 Chinese normal children. All of the subjects were presented with three pictures for this eye-tracking task and 6 relative eye-movement parameters, first fixation duration, average fixation duration, average saccade amplitude, mean saccade distance, fixation frequency and saccade frequency were recorded for analysis.

Results

Analyzing the relative parameter among three pictures, except for the fixation frequency and the saccade frequency, other eye-movement parameters were significantly different among the three pictures (P <0.05). Among the three pictures, the first fixation duration was longer, and the average fixation duration, the average saccade amplitude and the mean saccade distance were shorter from picture 2 to picture 3. Comparing all eye-movement parameter between the two groups, the scores of average saccade amplitude (P=0.017) and the mean saccade distance (P=0.02) were less in the dyslexia group than in the normal group (P <0.05), other parameters were the same in the two different groups (P>0.05).

Conclusions

The characteristics of the pictures can significantly influence the visuospatial cognitive processing capability of the Chinese children. There is a detectable disability for the Chinese dyslexic children in the visuospatial cognitive processing: their saccade amplitude and mean saccade distance are shorter, which may be interpreted as specific for their reading disability.
Effect of multiple-phase regional intra-arterial infusion chemotherapy on patients with resectable pancreatic head adenocarcinoma
Authors: JIN Chen , YAO Lie , LONG Jiang , FU De-liang , YU Xian-jun , XU Jin , YANG Feng , NI Quan-xing
Published: January 2024

Background

Regional intra-arterial infusion chemotherapy (RIAC) has been more valuable to improve prognosis and quality of life of patients with inoperable pancreatic adenocarcinomas, and adjuvant RIAC plays an important role in prolonging survival and reducing risk of liver metastasis after radical resection of pancreatic cancer, but the effect of preoperative or multiple-phase RIAC (preoperative combined with postoperative RIAC) for resectable pancreatic cancers has not been investigated. In this prospective study, the effect of multiple-phase RIAC for patients with resectable pancreatic head adenocarcinoma was evaluated, and its safety and validity comparing with postoperative RIAC were also assessed.

Methods

Patients with resectable pancreatic head cancer were randomly assigned to two groups. Patients in group A (n=50) were treated with new therapeutic mode of extended pancreaticoduodenectomy combined with multiple-phase RIAC, and those in group B (n=50) were treated with extended pancreaticoduodenectomy combined with postoperative RIAC in the same period. The feasibility, compliance and efficiency of the new therapeutic mode were evaluated by tumor size, serum tumor markers, clinical benefit response (CBR), surgical complications, mortality and toxicity of RIAC. The disease-free survival time, median survival time, incidence of liver metastasis, survival rate at 1, 2, 3 and 5 years were also observed. Life curves were generated by the Kaplan-Meier method.

Results

The pain relief rate and CBR in group A was 80% and 84% respectively. Serum tumor markers decreased obviously and tumors size decreased in 26% of patients after preoperative RIAC in group A. No more surgical complications, mortality or severe systemic side effects were observed in group A compared with group B. The incidence of liver metastasis in group A was 34% which was lower than 50% in group B. The disease-free survival time and median survival time in group A were 15.5 months and 18 months respectively. The 1-, 2-, 3- and 5-year survival rates were 54.87%, 34.94%, 24.51% and 12.25% respectively. There was no significant difference of survival time or survival rates between two groups.

Conclusions

Multiple-phase RIAC is effective in combined therapy of resectable pancreatic head carcinomas by enhancing inhibition of tumor growth and reduction of liver metastasis, without negative effect on patients' safety or surgical procedure.
Rhinoplasty in Chinese: management of lower dorsum and bulbous nasal tip
Authors: WANG Tai-ling , XUE Zhi-qiang , YU Da-shan , ZHANG Hai-ming , TANG Xiao-jun , WANG Jia-qi , YANG Xin , LUO Jia-lin , MA Ji-guang
Published: January 2024

Background

Bulbous nasal tips and lower dorsa are common facial features in Chinese people, and surgery to reshape these is frequently requested. The use of silicone implants in rhinoplasty has been widely used in China for many years, but is not suitable for patients seeking Caucasian tip shapes. The creation of an excessively high tip supported only by a silicone implant inevitably leads to implant extrusion. Although many rhinoplasty techniques have been used in Caucasian patients, there is currently no suitable method for Chinese patients, whose anatomy differs from that of Caucasians. The present study was aimed to investigate the clinical outcome of a novel method of rhinoplasty in Chinese people.

Methods

Eighty patients underwent rhinoplasty using our method between 2002 and 2006. We classified the patients into three types, according to the distance between tip defining points, and used different techniques accordingly. Furthermore, an innovative cartilage carving method and a tip fibro-fatty tissue flap were designed and combined with traditional techniques, such as insertion of silicone implant, cartilage grafts, suture techniques and cephalic trimming to reshape the nasal contours. The followup period was 10–60 months (average, 21 months).

Results

Remarkable modifications in nasal contours were achieved. No complications developed in any of the 80 patients. Seventy-eight patients were satisfied with the results. The outcomes remained unchanged over time.

Conclusion

Our method is effective and suitable for the treatment of Chinese patients with lower dorsa and bulbous nasal tips.
Mast cell degranulator compound 48–80 promotes atherosclerotic plaque in apolipoprotein E knockout mice with perivascular common carotid collar placement
Authors: TANG Ya-ling , YANG Yong-zong , WANG Shuang , HUANG Tao , TANG Chao-ke , XU Zeng-xiang , SUN Yu-hui
Published: January 2024

Background

Study of the relationship between mast cells and atherosclerosis is mostly dependent on pathological observation and cytology experiments. To investigate the effects of mast cells degranulation on plaque and their possible mechanisms we used apolipoprotein E knockout mice which had been placed perivascular common carotid collar with mast cells degranulator compound 48–80.

Methods

Forty apolipoprotein E knockout mice were fed a western-type diet and operated on with placement of perivascular right common carotid collar. Four weeks after surgery, the mice were intraperitoneally injected with compound 48–80 (0.5 mg/kg) or D-Hanks every other day for 4 times. The serum lipids and activity of tryptase were measured. Tissue sections were stained with hematoxylin and eosin. Corresponding sections were stained with toluidine blue and immunohistochemically with antibodies against macrophage-specific antigen, α-smooth muscle actin, interleukin-1 β and von Willebrand factor. Simultaneously, basic fibroblast growth factor was detected by in situ hybridization and immunofluorescence.

Results

No pathological change was observed in common carotid non-collar placement but atherogenesis in common carotid collar placement of both groups. There was a significant increase in plaque area ((5.85±0.75)×104 vs (0.86±0.28)×104μm2, P <0.05), the degree of lumen stenosis ((81±15)% vs (41±12)%, P <<0.05), the activity of tryptase in serum ((0.57±0.13) U/L vs (0.36±0.10) U/L, P <0.05), and the percentage of degranulated mast cells ((80.6±17.8)% vs (13.5±4.1)%, P <0.05). The expressions of macrophage-specific antigen, α-smooth muscle actin, interleukin-1 β, basic fibroblast growth factor and the density of neovessel in plaque were more in the compound 48–80 group than in the control group.

Conclusions

Perivascular common carotid collar placement can promote atherosclerotic plaque formation in apolipoprotein E knockout mice. Compound 48–80 increases plaque area and the degree of lumen stenosis by the mechanism that compound 48–80 promotes proliferation of smooth muscle cells and aggregation of macrophages. Compound 48–80 promotes angiogenesis in plaque. The mechanism is potentially that compound 48–80 increases the expressions of basic fibroblast growth factor mRNA and protein in plaque. Compound 48–80 enhances the expression of interleukin-1 β in plaque.