bluuebunny/crossref_metadata_2025 huggingface dataset:
BACTENECINS AS CELL-PENETRATING PEPTIDES
Authors: Shamova O V , Nazarov A S , Kopeykin P M , Kudryavtsev I V , Grudinina N A , Andreeva E A , Milman B L , Orlov D S
Published: February 2020

Cell-Penetrating Peptides (CPPs) are molecules that can easily internalize into eukaryotic cells, as well as deliver across their membranes a variety of compounds (proteins, nucleic acids, liposomes, nanoparticles, etc.). CPPs are considered as promising components of anticancer drugs, serving for delivery of active ingredients into malignant cells, therefore, a detailed study of a mechanism of action of CPPs and search for novel, more effective peptides are vital tasks of current biological and medical research. An ability of proline-rich peptides bactenecins (ChBac5, ChBac3.4, mini-ChBac7.5Na) and their truncated variants to penetrate into eukaryotic cells has been explored. By means of flow cytometry and confocal microscopy, we found that these peptides, tagged with a fluorescent dye BODIPY FL, rapidly penetrated into tumor cells and, to a lesser extent, into normal mammalian cells in vitro. The dependence of the internalization process on the medium temperature and energy metabolism of target cells was studied. The obtained data on the cell-penetratin activity of caprine bactenecins confirm the prospect of further investigations of these peptides as prototypes of new compounds - carriers of drugs into malignant or infected cells.
EFFECT OF rTMS ON BLOOD CONTENT OF DEHYDROEPIANDROSTERONE-SULFATE (DEAS) AND CORTISOL IN MEN AND WOMEN WITH PARKINSON’S DISEASE (PD): A PILOT PLACEBO-CONTOLLED STUDY
Authors: Zhanaeva S Ya , Gevorgyan M M , Dzemidovich S S , Kulikova K I , Idova G V , Danilenko K V , Aftanas L I
Published: February 2020

PD is a neurodegenerative disease characterized with loss of dopamine neurons and associated with neuroinflamation and unbalanced in HPA-axis. We investigated the content of cortisol and DEAS - hormones of HPA-axis in patients with PD after applying rTMS. Feng S.F. et al. (2012) showed that rTMS improves the balance of HPA axis hormones during depression, which is one of the non-motor manifestations of PD. PD patients were randomized into groups with active rTMS (13 men, 11 women) and sham rTMS (10 men, 15 women).The 10Hz rTMS was performed sequentially over 2 targets: the primary motor cortex and the DLPFC daily for 20 days. Outcome measures included the indicators of MDS-UPDRS (Part 3) scale, content of cоrtisol and DEAS in the peripheral blood.The Motor Examination Part scores demonstrated clinically meaningful improvement only in the active treatment group (p < 0.01). The content of the DEAS in this group was negatively correlated with indicators of scales of clinical manifestations, stress and anxiety (p < 0.05). In this group an increase of content of DEAS in the peripheral blood of men was found (p < 0.01, Wald-Wolfowitz Runs Test). Thus, the rTMS increases the levels of a wellknown neuroprotective hormone and a modulator of DA activity DEAS only in men.
MAST CELLS AFTER BONE MARROW AUTOTRANSPLANTATION
Authors: Vorobyova O V , Lyubovtseva L A , Guryanova E A , Gimaldinova N E
Published: February 2020

Purpose: to study bone marrow mast cells in mice after autotransplantation. Materials and methods. Mast cells and sulphatedness degree of heparin mucopolysaccharide in the bone marrow were identified using Unna staining with polychromatic toluidine blue. Study results. Data on mast cells distribution in the bone marrow after autotransplantation in 40 minutes and in 2 hours were analyzed. Two types of mast cells’ reaction to autologous bone marrow introduction were identified: sequential degranulation and exocytosis. As a result, secretion of mast cells causes production of biologically active substances in the microenvironment of a mast cell; these substances form chains and conglomerates from granules, changes in the number of which can contribute to changing the process of mitotic division. According to morphological criteria three populations of mast cells were identified: small-sized cells, with blue-colored nuclei stained orthochromatically and located asymmetrically; metachromatic oval-shaped cells with a nucleus located in the centre; large, degranulated, gamma-metachromatic mast cells. Most part of mast cells in bone marrow smears is presented by integral forms. Heparin in mast cells takes part in regulating metabolism in the bone marrow after autotransplantation.
THE CHARACTER OF SYSTEMIC CHANGES IN ADAPTIVE AND INNATE IMMUNE RESPONSE IN PATIENTS WITH MULTIPLE SCLEROSIS
Authors: Andreeva I I , Sizyakina L P , Goncharova Z A
Published: February 2020

The article presents the results of a comprehensive analysis of the parameters of innate and adaptive immunity in 85 patients with recurrent remitting multiple sclerosis (MS) with its exacerbation (54 people) and in conditions of persistent clinical remission (31 people). It is shown the signs of autoinflammation and increased reactivity of the T-link of adaptive immunity to be registered not only in exacerbation, but also in remission. The revealed changes determine the pathogenetic basis of MS progression and they should be taken into account when accompanying patients in remission to prevent clinical activation.
INFLUENCE OF ENDOCRINE PATHOLOGY ON NEUROIMMOUNS INTERACTIONS IN PLACENTA
Authors: Drobintseva A O , Andreev A E , Makarenko S V , Medvedev D S , Soldatova Y A , Polyakova V O
Published: February 2020

According to statistics, approximately 75-80% of cases of diabetes mellitus in women during pregnancy show the presence of a urogenital infection in which the development of the inflammatory process is conducive to the elimination of the pathogen and the appearance of necrotic tissue. Such inflammatory processes, as a rule, occur with the participation of macrophages attracted by B-lymphocytes and NK-cells. The main goal of this study was to evaluate the expression ratio of immunocompetent cells: macrophages, NK cells and B lymphocytes in the placenta in women with diabetes mellitus who are in different age groups. Molecular markers were visualized using an immunoistochemical method. Were used antibodies to CD68 (1:300, Dako, USA) for macrophages, CD20 (1:300, Dako, USA) for B-lymphocytes and CD57 (1:300, Dako, USA) for natural killer cells. The results were visualized on a confocal microscope (FluoView 1000 (Olympus)). For scoring of microphotographs program “Morphology 5.2” was used. On the microphotographs the relative area of expression was evaluated, signified as the ratio of the area of the immunopositive reaction to the total area of the slide and the optical density. Then a statistical evaluation of the obtained data in the “Statistic 10.0” program was carried out. During the experiment, a sharp decrease in the expression of the CD68 marker in the placenta was detected. A decrease in the expression of the CD20 marker with an increase in the age of patients with diabetes mellitus was also demonstrated, while in healthy women an increase was observed in the middle age group. For natural killers, there was no difference between healthy and sick women. The result indicates a weakening of the reaction of the immune system in diabetes mellitus.
NEUROIMMUNE MECHANISMS OF COGNITIVE IMPAIRMENT AT AFFECTIVE DISORDERS
Authors: Goldin B G
Published: February 2020

The aim of this study was the identification of the neuroimmune mechanisms of cognitive impairment on the basis of investigation of an of cognitive disorders association with functional activity of blood mononuclear cells and the synthesis of tumor necrosis factor - α (TNF-α) in patients with affective disorders in the form of depressive reactions and depression.TNF-α expression level in blood mononuclear cells of patients conducted with using the reverse transcriptase polymerase chain reaction method. The proliferative activity of blood mononuclear cells was investigated by a standard method based on the inclusion of a radioactive label. Cognitive function was assessed on the basis of perception, memory, praxis, speech, and control function. The severity of affective symptoms was measured by the Hamilton scale. It was found that patients with depressive reactions were characterized by the mild non-elemental cognitive impairment; while, in patients with depression, more severe non-elemental cognitive impairments in the form of decreased attention, memory, and daily activity were observed. In patients with affective disorders in the form of depression, an increase in the synthesis of TNF-α in blood mononuclear cells was detected, both an increase of the expression frequency of its gene and an increase in mRNA level, as well as an increase of the proliferative activity of blood mononuclear cells, which indicates the presence of immune system dysfunction in this category of patients.Thus, in patients with depression, activation of the TNF-α synthesis in blood mononuclear cells occurs: an increase in the frequency of its expression and an increase of the level of mRNA; these changes are accompanied by the increasing of immune cells functional activity and moderate non-delicate cognitive disorder in the form of cognitive impairment.
PRESERVED NUMBER OF OREXIN NEURONS IN POSTMORTEM HYPOTHALAMIC TISSUE OF CHRONIC ALCOHOLICS
Authors: Kudriavova A S , Meskenaite V , Mikhailov V I , Schesny M , Korneva E A , Gavrilov Y V , Valko P O
Published: February 2020

The hypothalamic orexin system is critically involved in addiction, including chronic alcohol abuse. Microinjection of orexin into the lateral hypothalamus increases alcohol intake in rats, while reduced immunoreactivity of orexin neurons is associated with decreased alcohol drinking. Recently, the numbers of orexin neurons were found to be increased in opiate addiction in humans [4] and cocaine addiction in rats [2], but the integrity of orexin neurons has not yet been studied in human alcoholics. We examined the hypothalamus of 9 patients of chronic alcoholism and 10 subjects without a history of alcoholism or any other neurological or psychiatric disorder. We performed immunohistochemistry for orexin A, followed by stereological quantification. The hypothalamic tissue of chronic alcoholics exhibited a slightly increased number (9%) of orexin-containing neurons compared to the control group (123’087 ± 18’536 and 110’431 ± 14’439, p = 0.11). Mean Gundersen’s coefficient of error was 0.06 ± 0.01. The number of orexin neurons was similar in chronic alcoholics and control subjects without a history of alcoholism. Further examination of alcohol-induced hypothalamic damage is needed to understand, whether a neuroplastic increase in orexin neurons counterbalances a concurrent alcohol-toxic damage to these neurons.
PENGEMBANGAN MULTIMEDIA INTERAKTIF BERBASIS AUTOPLAY SEBAGAI MEDIA PROMOSI KESEHATAN TENTANG KESEHATAN GIGI DAN MULUT PADA SISWA KELAS V SDN PERCOBAAN 02 KOTA MALANG
Authors: Setiawan Heri , Adi Sapto , Ulfah Nurnaningsih Herya
Published: February 2020

Abstrak: Penelitian ini bertujuan untuk menghasilkan media promosi kesehatan berupa multimedia interaktif berbasis autoplay di SDN Percobaan 02 Kota Malang. Metode penelitian yang digunakan adalah penelitian dan pengembangan yang telah disesuaikan dengan kemampuan peneliti. Teknik pengumpulan data menggunakan analisis kebutuhan dan angket penilaian yang diberikan untuk siswa dan ahli media serta ahli materi. Teknik analisis yang digunakan adalah analisis deskriptif sesuai prosedur pengembangan. Kesimpulan dari hasil penelitian pengembangan ini adalah multimedia sangat layak atau valid digunakan bagi siswa kelas 5 SDN Percobaan 02 Kota Malang. Hasil produk akhir multimedia interaktif tentang kesehatan gigi dan mulut belum diketahui seberapa besar pengaruhnya terdapap peningkatan pengetahuan siswa, maka perlu dilakukan penelitian lanjutan terkait hal tersebut.Kata kunci: multimedia, interaktif, autoplay, kesehatan gigi dan mulutAbstract: This study aims to produce health promotion media in the form of interactive multimedia based on autoplay in SDN Percobaan 02 Kota Malang. The research method used is research and development that has been adapted to the ability of researchers. Data collection techniques use needs analysis and assessment questionnaire given to students and media experts and material experts. The analysis technique used is descriptive analysis according to the development procedure. The conclusion of the results of this development research is a very feasible or valid multimedia used for 5th grade students SDN Percobaan 02 Kota Malang. The result of interactive multimedia product about dental and oral health is not known how much influence the student's knowledge increase, hence need to do further research related to that matter.Keywords: multimedia, interactive, autoplay, oral and dental health
HUBUNGAN ANTARA FAKTOR PERILAKU ORANG TUA DENGAN KEJADIAN PNEUMONIA BALITA DI WILAYAH KERJA PUSKESMAS DINOYO KOTA MALANG
Authors: Pratiwi Dinar Septi , Yunus Moch. , Gayatri Rara Warih
Published: February 2020

ABSTRAK: Penelitian ini bertujuan untuk mengetahui hubungan antara faktor perilaku orang tua dengan kejadian pneumonia balita di wilayah kerja Puskesmas Dinoyo Kota Malang. Penelitian ini menggunakan metode korelasional dengan rancangan penelitian cross sectional study, dengan sampel penderita pneumonia balita dan penderita bukan pneumonia/ISPA di wilayah Puskesmas Dinoyo Kota Malang yang memenuhi kriteria inklusi masing-masing sebanyak 30 sampel menggunakan perbandingan 1:1. Teknik pengambilan sampel menggunakan non-probability sampling dengan pendekatan accidental sampling. Pengumpulan data dilakukan dengan cara wawancara menggunakan kuesioner kepada orang tua penderita. Sedangkan teknik analisa data menggunakan uji chi square test for association dengan taraf signifikansi 0,05 atau (p < 0,05). Berdasarkan hasil analisis data terdapat korelasi yang signifikan antara kebiasaan merokok orang tua, kebiasaan mencuci tangan setelah batuk/bersin, kebiasaan membuka jendela kamar tidur dan kebiasaan membuka jendela ruang tamu.Kata kunci: pneumonia, balita, faktor perilaku orang tua.ABSTRACT: This study aims to determine the relationship between behavioral factors of parents with the incidence of pneumonia toddlers in Puskesmas Dinoyo Kota Malang. This study used correlational method with cross sectional study design, with sample of pneumonia infants and non-pneumonia/ARI patients in Puskesmas Dinoyo Kota Malang which fulfilled the inclusion criteria of 30 samples using 1: 1 ratio. The sampling technique used non-probability sampling with accidental sampling approach. Data collection was done by interview using questioner to the patient's parents. While technique of data analysis used chi square test for association with significance level 0,05 or (p <0,05). Based on the results of data analysis there is a significant correlation between parents' smoking habits, hand washing habit after coughing/sneezing, the habit of opening the bedroom window and the habit of opening the living room window. Keywords: pneumonia, toddlers, behavioral factors of parents
HUBUNGAN KUALITAS PELAYANAN PERSALINAN DENGAN KEPUASAN IBU BERSALIN DI RUMAH SAKIT IBU DAN ANAK (RSIA) SRIRATU MEDAN TAHUN 2019
Authors: Ndruru Desi Lustiyani Putri , Wau Herbert , Manalu Putranto
Published: February 2020

Pembangunan kesehatan adalah upaya untuk meningkatkan kesadaran, kemauan, serta kemampuan setiap orang untuk dapat berperilaku hidup sehat untuk mencapai derajat kesehatan yang setinggi-tingginya.Layanan kesehatan yang berkualitas adalah layanan kesehatan yang efisien, sebaliknya layanan kesehatan yang kurang atau tidak bermutu adalah akan membuat layanan organisasi menjadi sangat boros dan mengelurkan biaya yang mahal. Berdasarkan hasil survei awal yang telah dilakukan, data kunjungan ibu bersalin di Rumah Sakit Ibu dan Anak (RSIA) Sri Ratu Medan dalam 3 tahun terakhir menunjukan angka yang menurun pada tahun 2015 sebanyak 681 ibu bersalin, tahun 2016 sebanyak 573 ibu bersalin, tahun 2017 sebanyak 505 ibu bersalin. Hal ini dikarenakan sudah banyaknya persaingan antar rumah sakit mengenai kualitas pelayanan persalinan yang cukup memberikan kepuasan bagi ibu bersalin. Penelitian ini bertujuan untuk mengetahui hubungan kualitas pelayanan persalinan dengan kepuasan ibu bersalin di RSIA Sri Ratu Medan. Metode penelitian yang digunakan adalah penelitian kuantitatif dengan pendekatan cross sectional. Populasi dalam penelitian ini adalah pasien ibu bersalin di RSIA Sri Ratu Medan dengan jumlah sampel 83 orang. Analisis dengan menggunakan uji chi square dengan α<0,05. Hasil penelitian menunjukan bahwa nilai p-value antara bukti fisik (p-value 0,001), kehandalan (p-value 0,000), daya tanggap (p-value 0,001), jaminan (p-value 0,115), perhatian (p-value 0,243) terhadap kepuasan ibu bersalin di RSIA Sri Ratu Medan. Kesimpulan: Terdapat hubungan yang bermakna antara bukti fisik, kehandalan, daya tanggap terhadap kepuasan ibu bersalin dan tidak terdapat hubungan yang bermakna antara jaminan dan perhatian terhadap kepuasan Ibu Bersalin di RSIA Sri Ratu Medan.
Biometric Authentication System Using Face Geometry
Authors: Chinwe C Ibebuogu , Seth Philip , Obiageli J Anyaduba
Published: February 2020

This seminar paper deals with biometric authentication, using human facial geometry as the login verification parameter. Biometric is the measurement and statistical analysis of human's unique physical and behavioral characteristics by mapping face geometry, fingerprints, iris, and voice. The aim of this seminar paper is to develop a functional Biometric Authentication System Using Face Geometry as the authentication method. Facial Geometry Authentication is a category of biometric technology that maps an individual's facial features mathematically and stores the data as face-prints in a database. Meanwhile the objective of this paper is to improve data access security, enhance identification accuracy, and contribute to the improvement of the existing facial recognition systems, focusing mainly on increasing its accuracy performance. On the other hand, hacking into users’ privacy, loss of confidential information, and high running costs, among others geared the motivation to develop a biometric authentication system using face geometry. Furthermore, the software engineering methodology adopted in this seminar paper is the Structural System Analysis and Design Methodology (SSADM). The software is developed in Visual C-sharp, and the database in SQL Server 2012; using Microsoft Visual Studio 2012 as the integrated development environment. Besides, OpenCV 2.4.8 library is used for image processing, image mapping, and computer vision.  The expected result of this seminar paper include: improved user data security, and increased efficiency in facial detection/recognition.
Design and Analysis Sensor Deployment Scheme for Underwater Communication
Authors: N L Taranath , S Y Shwetha , B.R. Chethan , L M Mr. Darshan
Published: February 2020

At the point while setting up the submerged acoustic sensor system (UASN), hub deployment will be the above all else errand, whereupon numerous basic system administrations, for example, system topology control, directing, & limit recognition, will be manufactured. Where hub deployment at 2-D physical remote sensor systems had been broadly concentrated, little consideration must be gotten through the 3-D partners.This paper goes for examining the effects for hub deployment procedures at localization exhibitions at the 3-D environment. All the more particularly, these re-enactments directed at this project uncover which of general tetrahedron deployment plan outflanks these irregular deployment plan & this 3D shape deployment plan as far as decreasing localization blunder & expanding localization proportion by keeping up these normal number for neighbouring anchor hubs & system availability. Given this way which arbitrary deployment will be essential decision for greater part of viable applications for date, the outcomes will be relied upon for reveal some insight onto the outline UASNs sooner rather than later.
Histomorphological Study of Leprosy with Clinical Correlation in Kumaon Region
Authors: Yadav Neha , Kumar Binay , Joshi Usha , Kumar Mukesh , Agarwal Saurabh
Published: February 2020

Background: Leprosy is a leading cause of permanent physical disability. Approx 60% of global burden of leprosy is represented by India. Histopathological examination is still considered gold standard for accurate categorization of leprosy so that timely treatment can be started.

Objectives:  To categorize and correlate types of leprosy clinically and histomorphologically in Kumaon region.

Methods: The present cross-sectional study of 62 cases was conducted in the Department of Pathology & Skin and V.D in a tertiary care centre of Kumaon region from August 2016 to April 2018. The cases were clinically examined and categorized according to Ridley-Jopling classification. Skin Biopsy and Slit-Skin Smear (SSS) were taken for accurate histomorphogical categorization of leprosy and assessment of bacterial index, followed by clinico-histomorphological correlation. Statistical analysis was done in term of chi-square test. Kappa test was used as agreement test for clinical versus histological classification of different type of leprosy.

Results:  A total of 62 clinically diagnosed leprosy cases evaluated histopathologically. Clinically, lepromatous leprosy (LL) was the most common type of leprosy (38.70%), followed by borderline tuberculoid (30.64%). On histopathological examination, indeterminate leprosy (IL) (21 cases; 33.90%) was the most common followed by lepromatous leprosy (16 cases; 25.80%).  Overall clinico-histopathological correlation was seen in 36 cases (58. 06%) with maximum correlation seen in indeterminate leprosy (100%) and tuberculoid leprosy (TT) (100%). Conclusion: This study concludes that correlation of clinical and histopathological features along with bacterial index is more useful for accurate typing of leprosy than considering any of the single parameter alone so that early and appropriate treatment could be started.
Adoption of innovations in harvesting methods of the grape: A case study in Charikar and Bagram districts of Parwan province, Afghanistan
Authors: Dadkhwah Zafaruddin , Demiryürek Kürşat
Published: February 2020

The main objectives of this study were to determine the extent of innovation in the grape harvest, and the rate of familiarity and usability of innovations by farmers in Parwan province. The data were collected as primary data, included face to face interviews with 120 grape growers and local authorities in 20 villages spread across the two districts of Charikar and Bagram provinces of Parwan, Afghanistan. The data was analyzed by (SPSS 22) Package. According to the results, the size of agricultural land, land allocated to grape production have the most similarities; however, the findings show that grape yield was impressed by the application of farmers' innovations and knowledge by the user of innovation in the harvest stage grape production. The membership of farmers in agricultural organizations is very weak, and only 8.2% of the farmers have membership in the organization. And also, the advantages and disadvantages of using innovations were evaluated. The advatages were evaluated by six options (Saving Time, Increasing demand for the product, Wastes Reduction in the product, Better management,  Easy harvest, Employment of less laborer), and all of them given high importance (HI). The disadvantages were evaluated in four options, of which only the the item ''Not economic'' was given (HI) while the remaining three disadvantages were in (LI) category. Familiarity and usability of innovations have different results; most of the farmers are familiar with innovations. However, the application of innovations is less than it is familiarity
Effects of the financial crisis on the turkish banking sector : a research on turkısh bankıng crısıs in 2000-2001
Authors: Behistani Jahan , ÖZYEŞİL Dr. Mustafa , Qadir Taimur A.
Published: February 2020

The objective of this paper is to give a theoretical structure that incorporates the inward development and elements of money related markets and organizations hypothesis keeping in mind the end goal to look at how the financial market and the managing an account part create pointers that influence financial development in Turkey. Incredibly, the choice of capital putting resources into request to obstruction against different sorts of dangers is a noteworthy issue for the banks. At this stage, an essential strategy to decide stretch testing is imperative whether the capital proportions of the banks are satisfactory or not.

The financial crisis of 2000-2001 was turned out to be devastating for Turkey after the plenitude of cash peg around the same time. The emergency being referred to originated from the deficient usage of controls, the insufficient profundity of the capital markets, the absence of evaluation of hazard, extreme loaning to consolidated establishments by national banks, confined financing costs, observed outside trade operations, constrained remote resource holding, the absence of rivalry, obstructions to remote section and high liquidity, endless swelling and a shortfall to be determined of installments.

Bank performance is one of the vital issues for the healthy functioning of the Turkish economy. I use surrogate scenarios to test flexibility of the banking sector. In this research I check how much banking sector is flexible to external shocks under the planned scenarios.

In this paper you can find so many objectives mean how you can examine your performance currently or in the past. The different panel data are collected that shows different perspective and views about the functionalism of the banking sector before and after the financial and economic crisis.
Práticas sociais de lazer e suas relações no espaço público Estação das Docas em Belém - Pará
Authors: Pereira Pablo Vitor Viana
Published: February 2020

O objetivo principal desta pesquisa foi analisar as práticas sociais de lazer e suas relações no espaço público Estação das Docas. Como procedimento metodológico optou-se por uma pesquisa descritiva analítica, com abordagem qualitativa, por meio da combinação entre levantamento bibliográfico e pesquisa de campo, além das entrevistas semiestruturada. A partir da análise dos dados pode-se constatar que no espaço do Complexo Turístico Estação das Docas, muitos usuários conseguem vivenciar o lazer, entretanto, de forma “regulada”, com certa vigilância, sem muita liberdade, visualizadas nas normas e regras impressas no “agir” dos funcionários, os quais utilizam de certa autoridade para dizer o que pode e o que não pode fazer no local. No entanto, novos usos acabam fazendo parte da cena e se instalando numa espécie de práticas sociais de lazer com certa liberdade, as quais imprimem pequenas transgressões ao que está imposto como norma, ou seja, percebeu-se que os usuários utilizam de artifícios e de estratégias para vivenciar o lazer.Palavras-chave: Práticas sociais de lazer. Espaços públicos. Estação das Docas.
Trauma mamario por mordedura de caballo - Reporte de caso
Authors: Camargo-Villalba Gloria Eugenia , Bustamange-Bohigas Pedro Manuel
Published: February 2020

Objetivo: presentar un caso de trauma mamario por mordedura de caballo en una mujer y revisar el manejo de este tipo de accidentes.Materiales y métodos: se presenta un caso de trauma mamario izquierdo por mordedura de equino, de 10 días de evolución, en una mujer de 43 años de edad atendida en una institución de primer nivel de complejidad, posteriormente remitida para estudio imaginológico y manejo a una institución de tercer nivel de complejidad. Se realizó una búsqueda de la información en las bases de datos SciELO y PubMed con la terminología MeSH “Bite horsebreast trauma”, y en español “trauma mamario por mordedura de equino”.Conclusiones: los traumatismos mamarios por mordedura de caballo son infrecuentes y pueden acompañarse de lesiones que van desde laceraciones, equimosis, hematomas, amputación de la glándula mamaria y complicaciones sistémicas de tipo infeccioso, así como secuelas severas de tipo funcional y estético. Es indispensable adoptar medidas preventivas generales y manejar secuencialmente el caso como se recomienda en el presente reporte.
A non-randomized study investigating the effectiveness of cognitive reframing in socially disconnected widows
Authors: MOSES Victor
Published: February 2020

Objectives:
Socially
disconnected widows usually live a lonely and depressing life with anxiety and
low self-worth. Many have contemplated suicide and others have become a victim
of suicide already. Evolving an intervention to provide succor to them to take
control of their lives may help a great deal. This paper presents the results
of a nonrandomized study assessing the potency of cognitive reframing (CR) in
reducing social disconnectedness (SD) among the widows.Methods: The
pre- and post-data was collected from a non-randomized sample of 41 widows in
the treatment group and 45 in the waitlist control group. The mean age of the participants was 41.383 ± 6.730 [95% CI = 39.940–42.940] (min. = 25 - max. = 56) years. The
cognitive reframing administered spanned for eight weeks.Results: Analysis
of the data collected suggests that cognitive reframing is significantly
effective in reducing socially disconnected behavior among the widows in the
study. The social disconnected behavior among the widows reduced by 40.95%
compared to 8.29% observed in the waitlist control group.Conclusions: The CR technique may be helpful in
reducing social disconnectedness in widows. However, further study may be
required in a randomized sample to enhance generalization.
Ultrasound-guided axillary approach for brachial plexus block reduces block onset time compared to midhumeral approach
Authors: KESKE Aylin , BAŞKAN Semih , İSMAİL Aytaç , LAFÇI Ayşe
Published: February 2020

Aim: Brachial plexus block
under ultrasonography guidance is a successful and frequently used anesthesia
method for hand, wrist and forearm surgery. Brachial plexus block can be performed with axillary
or midhumeral approach technique. In
this study, we aimed to compare the intraoperative and postoperative anesthetic
and analgesic properties of axillary or midhumeral approach in
ultrasonography-guided brachial plexus block.Material and Methods: This randomized,
controlled, double-blind, single-center study included 90 ASA I-III risk
patients, aged 18-70 years, who underwent hand, wrist and forearm surgery. In Group I, axillary; in Group II, midhumeral approach techniques were
performed for brachial plexus block. Cold test was used to evaluate sensory
block, and three-point scale was used to evaluate motor block. Postoperative
pain was assessed by visual analog scale.Results: There was no
statistical difference between age, height, weight, BMI and gender
characteristics of the patients included in the study. There was no
statistically significant difference between the groups in terms of block onset
and regression times on both sensory and motor examination (p> 0.05). The
main result was that axillary approach shortens the complete block onset time
on both sensory and motor examination (p <0.05). Another important result
was that axillary approach provides higher surgeon and patient satisfaction
levels significantly comparing to mid-humeral approach (p <0.05).

Conclusion: Both approaches can be applied
successfully in brachial plexus block and can be used effectively in elective
surgeries. In patients who underwent axillary approach technique for brachial
plexus block, full block onset time is earlier than in patients undergoing
midhumeral approach technique. Therefore, axillary approach technique may be
preferred in cases requiring urgent surgical intervention.
Investigation of the complication, morbidity and mortality factors affecting the clinical hospitalization process after femoral hernioraphy
Authors: DÜLGER Dilek , AYDIN Feray , ALBUZ Özgür
Published: February 2020

Aim: The
study aims to investigate the risk factors of patients with femoral hernia as
well as factors that affect the
hospitalisation process, morbidity and mortality, particularly in terms of
gender.

 

Material
and Methods: A
total of 65 femoral hernia surgeries were performed in 29 Mayıs Public Hospitals between January 1, 2015 and June 30,
2019. Six patients with incomplete or unclear data were excluded, and the data
of 59 patients were analysed. Percentage and frequency were used for discrete
variables, whereas mean and standard deviation for continuous variables.
Student’s t-test was used for independent variables according to the
distribution status, whereas chi-square test was used for dichotomous
variables, and the results for binary logistic regression were obtained.

 

Results:
Males were significantly more likely to have femoral hernia risk during old age
[66.11years vs. 52.68 years (p=0.004), adjusted odds ratio (AOR): [0.87 (0.784,
0.969)(p= 0.011)]. In student’s t-test, male patients had shorter length of
hospital stay (LOS). Hovewer the p value was found 0.79. In the binary multiple
logistic regression for LOS value; In terms of gender, body mass index (BMI,
kg/m2), age and complications; P value was found as 0.07 and ; AOR was found
2.2. With this result; The females have got the more LOS value than men as
statistichally, for p=0.1 value.

Conclusion:
Femoral hernia frequently occurs in women; however,
we found that its higher incidence
is also can be found in men during old age, and after surgery, men are
generally discharged earlier than women.
Opodatkowanie nieodpłatnego nabycia własności rzeczy i praw majątkowych w prawie podatkowym Polski i Litwy. Wybrane problemy
Authors: Babiarz Stefan
Published: February 2020

Z przedstawionych porównań wynika ewidentnie, że obowiązujący w Republice Litewskiej podatek od spadków jest podatkiem prostym, nieskomplikowanym zarówno pod względem prawnym, jak i finansowym. Tym samym nie wywołuje on poważniejszych problemów praktycznych ani w jego płaceniu, ani w wymiarze. Jego obliczenie i wymiar są przyjazne dla podatników.

Na szczególną uwagę zasługują takie rozwiązania, jak obniżenie podstawy opodatkowania o 30%, brak odliczania długów i ciężarów oraz skomplikowanej procedury ich ustalania, respektowanie zasady unikania podwójnego opodatkowania czy brak instytucji ponownego powstania obowiązku podatkowego.

Tego nie można powiedzieć o obowiązującym w Polsce podatku od spadków i darowizn. Jedyne, co można powiedzieć na korzyść rozwiązań obowiązujących w Polsce, to to, że zakres przedmiotowy tego podatku jest szerszy, co prowadzi do niemożliwości poddania wielu przedmiotów nabycia wyższym podatkiem dochodowym od osób fizycznych.

Autor chce tym tekstem rozpocząć cykl publikacji przybliżających polskim podatnikom, organom podatkowym, a także ustawodawcy rozwiązania prawne obowiązujące w zakresie opodatkowania nieodpłatnego nabycia własności rzeczy i praw majątkowych w innych wybranych krajach europejskich.

Polska ustawa o podatku od spadków i darowizn jest niezwykle skomplikowana, generująca spory podatkowe, niesprzyjająca nawiązywaniu poprawnych relacji między podatnikami a organami podatkowymi i, niewątpliwie, także rodząca konflikty rodzinne.
China’s tax and non-tax instruments responding to its weakening attractiveness to foreign capital
Authors: Yusen Tan
Published: February 2020

This paper studies China’s weakening in its attractiveness to foreign capital, especially since its implementation of new corporate income tax law in year 2008, which phased out the former preferential tax treatments for foreign invested enterprises and the placed-based favourable tax policies for various special tax zones. Empirical evidence and the major factors causing this weakening in attracting foreign investment are discussed. This paper also studies the major tax measures, fiscal measures and non-tax measures adopted by China central and regional governments, which are aimed to improve China’s competitiveness in attracting foreign capital. The major contribution of this paper is its discussion on China’s good practice of making use of nonta Xmeasures to attract foreign capital, which is effective in avoiding harmful international ta Xcompetition. The other contribution of this paper is the discussion on the economic foundation (i.e. China’s comparative strength and state ownership of lands) which makes these non-tax measures feasible. China’s good practice of adopting non-tax measures and making use of its comparative strength is of reference value to other capital importing countries in the world.
Experimental Infection of Adapted Influenza B Virus in Mice Model
Authors: Prokopyeva Elena , Kurskaya Olga , Sobolev Ivan , Solomatina Mariia , Murashkina Tatyana , Suvorova Anastasia , Alekseev Alexander , Danilenko Daria , Kommissarov Andrey , Fadeev Artem , Shestopalov Alexander , Dygai Alexander , Sharshov Kirill
Published: February 2020

Over the years influenza B virus (IBV) contribute annual disease and can lead to serious respiratory disease among humans. More attention should be paid to the mammalian adaptive processes of B viruses and development of vaccines against current influenza. Because of preclinical trials of anti-influenza drugs are conducted mainly on mice, we developed adequate animal model using antigenically-relevant IBV strain for testing anti-influenza drugs and protective efficacy of flu vaccines. We serially passaged Victoria lineage (clade 1A) IBV 17 times in BALB/c mice. The adaptive amino acid substitutions were found in HA (T214I) and NA (D432N). By the electron microscopic examination, we showed spherical and elliptical shapes of IBV. Light microscopy showed that mouse-adapted B virus caused influenza pneumonia on day 6 post inoculation. We evaluated the illness pathogenicity, viral load and histopathological features of mouse-adapted IBV and estimated anti-influenza drugs and vaccine efficiency in vitro and in vivo. Assessment of investigational anti-influenza drug oseltamivir ethoxisuccinate and flu vaccine Ultrix® revealed effectivity against our mouse-adapted influenza B virus.
A Configuração da Disciplina Escolar Matemática: Professores do Atheneu Sergipense
Authors: Alves Eva Maria Siqueira
Published: February 2020

Desde os primeiros momentos de organização dos estudos secundários em Sergipe, há a presença das Matemáticas. Porém, cabe indagar: quem foram os professores responsáveis por ministrar essas aulas? Esse artigo investiga a história da disciplina escolar – Matemática no Atheneu Sergipense, tomando como eixo central e que transforma as finalidades em ensino, a pessoa do docente, determinante na configuração daquele saber nos estudos secundários, no período do final do século XIX e início do XX. As fontes analisadas são documentos produzidos por aquela Casa de Educação Literária, arquivados no Centro de Educação e Memória do Atheneu Sergipense, além das peças legislativas que possibilitam inferir sobre a história dos sujeitos ministrantes das aulas das Matemáticas.
Ensino Médio noturno: sentidos e significados dessa etapa da Educação Básica para alunos/as de uma escola pública do município de Anastácio – MS
Authors: Novais Sandra Nara da Silva , Silva Maria de Lourdes
Published: February 2020

Este artigo tem por objetivo identificar e descrever os sentidos e significados atribuídos à escola por um grupo de alunos/as concluintes do Ensino Médio noturno de uma escola pública localizada na periferia do município de Anastácio – Mato Grosso do Sul – no ano de 2009. Para melhor abarcar a temática investigada, aproximamo-nos, na construção do campo teórico-metodológico, de uma abordagem qualitativa. Dialogamoscom as leituras de Peregrino (2006); Navarro (2005); Mello (1999); Togni & Carvalho (2007); Kuenzer (2002), Freire (2000), (2005), Frigotto (2004), entre outros. Utilizamos, como procedimentos metodológicos, a revisãoda bibliografia sobre a temática investigada, pesquisa a documentos pertinentes à escola pesquisada, entrevistas semiestruturadas e registros das vozes dos sujeitos. Os diálogos com a bibliografia e com as vozes dos sujeitos apontam indícios de que a escola significa para eles uma oportunidade de melhoria das condições de vida individual e familiar, representa a possibilidade de inserção em setores mais qualificados do mundo do trabalho e possibilita o ingresso numa universidade. Consideram que a escola e os aprendizados no Ensino Médio têm valor, pois auxiliam a ver e a compreender as coisas de outro modo, o que contribui para serem pessoas mais felizes porque na escola aprenderam a conviver com as diferenças e a fazer amizades.
A Pedagogia Intercultural na Formação Docente para Educação de Jovens e Adultos – Compromisso Social das Ies no Brasil
Authors: Almeida Maria Josefa de Menezes
Published: February 2020

Este trabalho discute a problemática da ausência de formação docente específica para Educação de Jovens e adultos (EJa) no Brasil e, inserindo-se neste contexto apresenta o estudo que avalia uma proposta para a formação do professor em exercício da EJa. Esta análise se realiza através de estudo quaseexperimental intragrupal - pré e pós-teste com o objetivo de determinar os impactos da participação de professores no Curso: “Pedagogia Intercultural com ênfase na identidade cultural”. ao seu final, apresentam-se como resultados: a) positiva influência desta formação na prática docente dos participantes; b) aporte teórico a favorecer futuros estudos acerca do referido tema; e por fim, c) compromisso da Instituição de Ensino superior financiadora do estudo com a referida formação docente.
A educação e o movimento de defesa dos animais não humanos em Portugal na transição do século XIX para o Século XX
Authors: Amaro Alexandra , Felgueiras Margarida Louro , Lencastre Marina Prieto
Published: February 2020

As abordagens filosóficas conservacionista e protecionista atribuem o surgimento de inquietações sociais sobre os maus tratos infligidos aos animais não humanos em diversos países do ocidente, na transição do século XIX para o século XX. Este movimento social desafiou a visão hegemónica antropocêntrica, obteve a criação das primeiras áreas protegidas e organizou-se em associações de cidadãos, inquietos com o sofrimento animal, orientados para a proteção, prestação de assistência e defesa dos animais não humanos, procurando melhorar as condições em que eram mantidos, pela implementação de várias medidas: aprovar leis de proteção animal, desenvolver projetos para educar a população em geral e sensibilizar as crianças, ajudar a suprimir os maus tratos e promover a adoção de boas práticas na relação quotidiana com os referidos seres vivos. Este trabalho pretende tornar visível o processo histórico de organização de associações de defesa dos animais em Portugal, seus objetivos e ação educativa, analisar algumas medidas propostas e perspetivar historicamente os debates atuais sobre educação ambiental e a proteção animal. A pesquisa teve por base o Zoophilo, os estatutos da Sociedade Protectora dos Animaes e da Liga Nacional de Defesa dos Animais, os pareceres e o projeto de lei por ela apresentado à Assembleia Constituinte de 1910.
A Companhia de Jesus e o concílio de trento: aspectos pedagógicos da contra-reforma
Authors: Santos Fernanda
Published: February 2020

O propósito do concílio tridentino, no século XVI, foi reafirmar as doutrinas tradicionais e reorganizar o predomínio católico contra o avanço do protestantismo. Nesse contexto histórico surgiu a Companhia de Jesus, tendo grande destaque na Contra-Reforma. Este artigo pretende mostrar como projeto missionário e educativo jesuítico assumiu grande relevância entre os séculos XV e XVII, a partir da expansão de uma rede educativa religiosa. A Companhia desenvolveu também uma consciência nova em relação ao valor da educação. Assim, o objetivo principal deste artigo é mostrar a importância do colégio jesuíta como uma instituição global e abrangente, atentando na formação moral, espiritual e religiosa do estudante, a partir das decisões do concílio tridentino. Partindo do estudo da Ratio Studiorum, e dos planos de ensino propostos, procura-se analisar as principais modificações trazidas pela Contra-Reforma. O colégio foi o lugar escolhido para se ensinar formas concretas de moldagem de comportamentos que permitiram a aquisição detodo um acúmulo de saberes.
La institucionalización de la enseñanza de las literaturas espanhola e hispano-americanas en Brasil (1870- 1942)
Authors: Guimarães Anselmo
Published: February 2020

Este trabajo tiene como objetivo hacer una retrospectiva histórica de la enseñanza de las literaturas española e hispano-americanas, a través de la legislación educacional brasileña, informes, manuales, compendios y antologias publicados en Brasil. El período de recorte abarca el año de 1870, en el que se instituyó por primera vez em Brasil la enseñanza de la literatura española, hasta el año de 1942, cuando se publicó el Decreto-Ley 4244, que reformuló la enseñanza secundaria. En esta investigación utilicé los presupuestos teóricos asumidos por Chervel (1990), principalmente en lo que se refiere a las finalidades de la enseñanza, llevándose en cuenta su función de carácter pedagógico, político y cultural, mediante la adaptación de esas implicaciones al caso brasileño.
Formação de Professores da Educação Básica: projeto e proposições na Universidade Estadual do Maranhão
Authors: Silva Vanessa Nunes da , Pereira Isabel Cristina Auler
Published: February 2020

O principal objetivo deste estudo está centrado na aná- lise do projeto de formação de professores dos anos iniciais da Educação Básica em um polo pertencente à Universidade Estadual do Maranhão, integrante do Sistema Universidade Aberta do Brasil (UAB), situando-o no contexto da chamada Terceira Revolução Tecnológica ou a Sociedade do Conhecimento tendo como referência a formação do cidadão profissional, detentor de consciência crítica e inovadora. Para tanto, buscou-se analisar o projeto pedagógico do curso de Pedagogia a distância oferecido no polo de Fortaleza dos Nogueiras (Universidade Estadual do Maranhão - UEMA), no que concerne à concepção de educação a distância e de formação docente; bem como discutir de que forma se deu o processo de institucionalização do Sistema UAB nessas instituições de ensino superior. Constatou-se que não basta ter acesso a computadores conectados à internet; torna- -se imprescindível transformar informações em conhecimentos independentemente da hora ou local e que a tecnologia seja parte integrante do currículo.
Apresentação - Cultura, Formação e Mídia-educação
Authors: Fantin Monica , Zoboli Fábio , Mezzaroba Cristiano , Santos Silvan M.
Published: February 2020

Na busca do diálogo possível diferentes reflxões e prá-ticas educativas e culturais, o Número Temático Cultura,Formação e Mídia-educação percorre caminhos da es-tética, da arte e suas linguagens para sensibilizar nossoolhar às especifiidades das culturas infantis e juvenis esuas práticas na escola e fora dela.
Language Error Analysis on The Banner Nameplate in Magetan Regency
Authors: Dinda Ayu Saputri  , Kodrat Eko Putro Setiawan
Published: February 2020

This study aims to explain Indonesian language errors on signboards and banners in Magetan. The problem in this study is the mistake of using Indonesian on nameplate and banners in Magetan. The method used in the compilation of data uses a qualitative descriptive method of phenomenology. The data source in this study is a photo document that results from monitoring the use of Indonesian on signs and banners in the city of Magetan. For data retrieval techniques in this research using sampling snowball. The focus in Indonesian language error research on signboards and banners is on spelling, use of inappropriate sentences and foreign words.