bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH VOLUME EMISI KARBON, PENGUNGKAPAN EMISI KARBON, DAN TATA KELOLA PERUSAHAAN TERHADAP NILAI PERUSAHAAN
Authors: Afnilia Finni , Christina Dwi Astuti
Published: October 2023

Penelitian ini bertujuan untuk mengetahui pengaruh volume emisi karbon, pengungkapan emisi karbon, dan tata kelola perusahaan dengan indikator direksi, komisaris independen, komite audit terhadap nilai perusahaan. Sumber data penelitian ini adalah data sekunder yang bersumber dari laporan tahunan dan laporan keberlanjutan perusahaan yang terdaftar di Bursa Efek Indonesia (BEI). Adapun fokus penelitian ini adalah perusahaan energi dan barang konsumsi primer karena sektor-sektor tersebut memiliki kontribusi dalam menyumbang emisi karbon di Indonesia. Teknik pengambilan sampel dilakukan dengan teknik purposive sampling dan menghasilkan 81 perusahaan yang memenuhi kriteria. Metode analisis yang digunakan adalah analisis regresi data panel dan diolah dengan aplikasi software E-views versi 10. Hasil penelitian menunjukan bahwa direksi berpengaruh positif terhadap nilai perusahaan. Ukuran perusahaan berpengaruh negatif terhadap nilai perusahaan. Sedangkan volume emisi karbon, pengungkapan emisi karbon, komisaris independen, komite audit, dan leverage tidak berpengaruh terhadap nilai perusahaan.
PENGARUH AUDIT COMMITTEE CHAIRMAN CHARACTERISTICS DAN STRUKTUR KEPEMILIKAN TERHADAP MANAJEMEN LABA
Authors: Silitonga Jeremia , Hexana Sri Lastanti
Published: October 2023

Tujuan dari penelitian ini adalah untuk menguji bagaimana struktur kepemilikan dan sifat ketua komite audit mempengaruhi manajemen laba. Penelitian ini menggunakan metodologi pengujian hipotesis, dan data sekunder yang digunakan adalah laporan bisnis perbankan tahunan tahun 2019–2021. Strategi purposive sampling yang digunakan dalam metodologi pengumpulan sampel menghasilkan 43 perusahaan dan 129 sampel data. Hasil penelitian yang menggunakan teknik regresi linier berganda menunjukkan bahwa konsentrasi kepemilikan, usia ketua komite audit, dan banyaknya jabatan direktur ketua komite audit semuanya berdampak positif terhadap manajemen laba. Di sisi lain, kepemilikan institusional berdampak buruk terhadap pengelolaan laba. Tidak ada hubungan antara masa jabatan ketua komite audit, jenis kelamin, atau tingkat pengalaman akuntansi dan manajemen laba.
PENGARUH E-FILING, E-SPT DAN E-BUPOT UNIFIKASI TERHADAP KEPATUHAN WAJIB PAJAK DI DKI JAKARTA
Authors: Khairunnisa Ramadhanti Salma , Aqamal Haq
Published: October 2023

Penelitian ini bertujuan untuk menguji dan menganalisis pengaruh e-Filling, e-SPT dan e-Bupot terhadap kepatuhan wajib pajak di DKI Jakarta. Aplikasi e-Filling, e-SPT dan e-Bupot digunakan untuk membuat pelaporan perpajakan secara elektronik. Penelitian ini mengunakan metode kuantitatif dengan pengujian hipotesis untuk menjelaskan pengaruh antar variabel. Teknik pengambilan sampling ini mengunakan Nonprobability sampling. Metode penelitian ini menggunakan data primer yang berasal dari hasil responden pada pengisian kuesioner. Responden kuesioner pada penelitian ini berjumlah 100 responden yang disebarkan kepada wajib pajak di DKI Jakarta melalui google forms yang diolah dan dianalisis dengan model analisis linear berganda. Pengujian hipotesis mengunakan alat analisis SPSS. Berdasarkan hasil analisis penelitian menunjukkan bahwa e-Filling, e-SPT dan e-Bupot berpengaruh positif terhadap kepatuhan wajib pajak di lingkup DKI Jakarta.
PENGARUH CORPORATE SOCIAL RESPONSIBILITY DAN GREEN ACCOUNTING TERHADAP NILAI PERUSAHAAN DENGAN VARIABEL MODERASI PROFITABILITAS
Authors: Gunawan Hiemelda , Dwi Mulyani Susi
Published: October 2023

Dalam penelitian ini akan diteliti pengaruh CSR dan Green Accounting terhadap nilai perusahaan, profitabilitas sebagai variabel moderasi, dan ukuran perusahaan sebagai variabel kontrol. Purposive sampling digunakan sebagai teknik pengambilan sampel, sehingga menghasilkan sampel 180 untuk penelitian ini. Data yang digunakan berasal dari laporan tahunan perusahaan sektor energi yang terdaftar di Bursa Efek Indonesia tahun 2019 sampai dengan tahun 2021. Berdasarkan temuan penelitian, variabel Corporate Social Responsibility berpengaruh positif terhadap Nilai Perusahaan dan Green Accounting tidak berpengaruh terhadap Nilai Perusahaan. Variabel Profitabilitas tidak mampu memoderasi pengaruh Green Accounting terhadap Nilai Perusahaan dan mampu memperkuat pengaruh positif Corporate Social Responsibility terhadap Nilai Perusahaan.
PENGARUH BONUS PLAN, DEBT COVENANT, DAN POLITICAL COST TERHADAP OPINI AUDIT DENGAN PERATAAN LABA SEBAGAI VARIABEL PEMEDIASI
Authors: Kartini Farah Nabila , Deni Darmawati
Published: October 2023

Meneliti bagaimana biaya politik, perjanjian utang, dan program bonus mempengaruhi perataan laba dan opini audit adalah tujuan dari penelitian ini. Untuk melakukan penelitian ini, perusahaan-perusahaan di sektor infrastruktur, utilitas, dan transportasi yang akan terdaftar di Bursa Efek Indonesia (BEI) pada tahun 2020–2022 akan dijadikan contoh. Sebanyak 180 usaha dijadikan sampel penelitian ini, dan seluruhnya dipilih melalui teknik purposive sampling. Pendekatan regresi logistik digunakan untuk menguji hubungan antar variabel. Berdasarkan temuan penelitian tersebut, dapat dikatakan bahwa skema bonus dan perjanjian hutang sama-sama mempengaruhi perataan laba (income smoothing), political cost tidak berpengaruh terhadap perataan laba (income smoothing), income smoothing tidak berpengaruh signifikan terhadap opini audit, perataan laba mampu memediasi pengaruh bonus plan terhadap opini audit, perataan laba mampu memediasi pengaruh debt covenant terhadap opini audit, perataan laba tidak mampu memediasi pengaruh political cost terhadap opini audit.
ANALISIS PENGARUH LIKUIDITAS SAHAM, EARNING PER SHARE, RETURN SAHAM DAN PRICE EARNING RATIO TERHADAP KEPUTUSAN STOCK SPLIT
Authors: Pratama Yoga Dimas , Hotman Tohir Pohan
Published: October 2023

Penelitian memiliki tujuan guna memahami pengaruh likuiditas saham, return saham, earning per share, dan price earning ratio pada keputusan stock split. Penelitian mempergunakan metode kuantitatif dengan uji hipotesis dalam menerangkan pengaruh antar variabel. Data sekunder dari laporan tahunan perusahaan yang listing di BEI tahun 2018-2021 dipergunakan pada penelitian ini. Teknik sampling memanfaatkan metode purposive sampling dan didapatkan sejumlah 120 sampel dengan periode pengamatan tahun 2018 hingga 2021. Analisis regresi logistic dipergunakan untuk analisis data penelitian ini. Uji hipotesis pada penelitian mempergunakan SPSS 24. Berlandaskan hasil penelitian membuktikan return saham dan likuiditas saham tidak berpengaruh terhadap keputusan stock split, sementara EPS dan PER berpengaruh positif pada keputusan stock split.
FAKTOR-FAKTOR YANG MEMPENGARUHI REVALUASI ASET TETAP
Authors: Emir Fauzan Sudarso  , Laeli Dhikriyah
Published: October 2023

Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi revaluasi aset tetap. Metode pengambilan sampel yang digunakan adalah purposive sampling. Penelitian ini menggunakan 30 perusahaan yang terdaftar di Bursa Efek Indonesia yang memenuhi kriteria sampel selama penelitian dari 40 perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia pada tahun 2017-2020 maka total pengamatan adalah 120 sampel. Teknik analisis yang digunakan adalah analisis regresi logistik. Hasil penelitian ini menunjukkan Leverage, Firm size, market book ratio, Cash ratio, dan operating cash flow tidak berpengaruh terhadap revaluasi aset tetap. Fixed asset intensity, current ratio, quick ratio berpengaruh terhadap revaluasi aset tetap.
PENGARUH WHISTLEBLOWING SYSTEM TERHADAP DETEKSI FRAUD DENGAN AUDIT FORENSIK DAN AUDIT INVESTIGATIF SEBAGAI VARIABEL INTERVENING
Authors: Yasa I Wayan Kawistara , Aqamal Haq
Published: October 2023

Kasus kecurangan terjadi secara terus menerus dan konsisten meningkat setiap tahunnya. Salah satu bentuk kecurangan atau fraud adalah korupsi, korupsi banyak terjadi baik di sektor publik maupun sektor swasta. Tujuan dari penelitian ini adalah menguji secara empiris pengaruh whistleblowing system terhadap audit forensik, audit investigatif dan deteksi fraud serta menguji pengaruh whistleblowing system secara langsung dan tidak langsung terhadap deteksi fraud dengan audit forensik dan audit investigatif sebagai variabel intervening. Jumlah sampel dalam penelitian ini sebanyak 61 orang auditor yang bertugas di Kantor BPKP Perwakilan Provinsi Maluku Utara. Analisis data berupa persamaan Structural Equation Modeling (SEM) dengan menggunakan aplikasi SmartPLS. Hasil penelitian ini adalah (1) Whistleblowing system mempunyai pengaruh signifikan terhadap deteksi fraud. (2) Whistleblowing system mempunyai pengaruh signifikan terhadap audit forensik. (3) Whistleblowing system mempunyai pengaruh signifikan terhadap audit investigatif. (4) Audit forensik mempunyai pengaruh signifikan terhadap deteksi fraud. (5) Audit investigatif mempunyai pengaruh signifikan terhadap deteksi fraud. (6) Whistleblowing system terbukti berpengaruh signifikan terhadap deteksi fraud melalui audit forensik sebagai variabel intervening. (7) Whistleblowing system terbukti berpengaruh terhadap deteksi fraud melalui audit investigatif sebagai variabel intervening.
HALAL-LABELED FOOD SHOPPING BEHAVIOR: THE ROLE OF IMAGE, TRUST, AND SATISFACTION WITH ATTITUDE
Authors: Ridwan Muhammad , Luki Adiati Pratomo
Published: October 2023

This research aims to examine the shopping behavior of halal-labeled food and the role of several factors in shaping consumer attitudes. Indonesia is a country with the largest Muslim population in the world, leading to high consumption of halal products. The demand for halal food continues to rise in the global market, with the halal food industry expected to reach trillions of dollars by 2027. Brand image, trust, and satisfaction are believed to influence consumer attitudes in purchasing halal-labeled food. This study employs a quantitative approach with a survey method and a questionnaire as the data collection instrument. Respondents are asked to assess variables related to shopping behavior of halal-labeled food using a Likert scale. The research findings conclude that brand image, trust, and satisfaction positively influence consumer attitudes in buying halal-labeled food. Therefore, companies need to enhance brand image, strengthen trust, and ensure customer satisfaction to improve consumer attitudes towards halal-labeled food. By optimizing these factors, consumers are expected to be more inclined to purchase and consume halal food products, thereby supporting the growth of the halal food industry in Indonesia. The managerial implications of this research suggest that companies should reinforce their brand image, enhance consumer trust, and ensure customer satisfaction to cultivate positive attitudes towards halal-labeled food products
PENGARUH CORPORATE GOVERNANCE, CORPORATE RESPONSIBILITY DISCLOSURE, STRUKTUR MODAL, KOMISARIS INDEPENDEN TERHADAP NILAI PERUSAHAAN DENGAN PROFITABILITAS SEBAGAI VARIABEL MODERASI
Authors: Nafiisah Tiara Argi , Hermi
Published: October 2023

Penelitian ini bertujuan untuk mengetahui faktor yang mempengaruhi pengetahuan akuntansi dengan menjelaskan pengaruh Corporate Governance, Corporate Responsibility Disclosure, Struktur Modal, dan Komisaris Independen kepada suatu perusahaan. Penelitian ini menggunakan data sekunder. Variabel independen dalam penelitian ini Corporate Governance, Corporate Responsibility Disclosure, Struktur modal dan Komisaris Independen. Variabel dependen dalam penelitian ini adalah Nilai Perusahaan. Variabel moderasi dalam penelitian ini adalah Profitabilitas. Data penelitian diperoleh dari laporan tahunan yang dipublikasikan dalam BEI tahun 2018 – 2021. Teknik pengambilan sampel yang digunakan adalah purposive sampling yang diperoleh dengan total 9 perusahaan pada perusahaan sektor KBMI III. Penelitian ini menggunakan metode analisis regresi berganda. Hasil penelitian ini adalah (1) Corporate Governance tidak berpengaruh terhadap Nilai Perusahaan. (2) Corporate Responsibility Disclosure berpengaruh positif terhadap Nilai Perusahaan. (3) Struktur modal berpengaruh positif terhadap nilai perusahaan. (4) Komisaris Independen tidak berpengaruh terhadap Nilai Perusahaan. (5) Profitabilitas tidak menjadi variabel moderasi antara Corporate Governance, struktur modal dan Komisaris Independen dengan nilai perusahaan ataupun Profitabilitas (6) Corporate Responsibility Disclosure tidak berpengaruh terhadap nilai perusahaan. (7) Profitabilitas tidak berpengaruh terhadap variabel moderasi pada Struktur Modal. (8) Komisaris Independen tidak berpengaruh terhadap profitabilitas.
PENGARUH DIGITAL MARKETING TERHADAP PURCHASE INTENTION: DIMODERASI BRAND EQUITY
Authors: Arieantony  , Ina Oktaviana Matusin
Published: October 2023

Penelitian ini bertujuan untuk menguji secara empiris dan membuktikan pengaruh pemasaran digital terhadap niat membeli, selain itu, juga mencoba menguji dan membuktikan bahwa ekuitas merek dapat memoderasi pengaruh pemasaran digital terhadap niat membeli. Kriteria sampel dalam penelitian ini adalah individu yang menggunakan Tokopedia, berusia minimal 20 tahun, dan berdomisili di Indonesia. Sampel penelitian diambil melalui metode yang disebut purposive sampling yang berasal dari kuesioner Google Form yang dibagikan kepada 75 responden. Analisis data menggunakan aplikasi SmartPLS versi 3 dengan menggunakan metode Partial Least Square (PLS). Hasil penelitian ini menunjukkan bahwa terdapat pengaruh pemasaran digital terhadap niat membeli, dan terdapat pengaruh ekuitas merek pada pemasaran digital terhadap niat membeli. Diharapkan temuan ini dapat meningkatkan manajemen perusahaan dalam mengembangkan strategi pemasaran digital yang terkait untuk meningkatkan penggunaan fasilitas yang tersedia pada layanan aplikasi Tokopedia.
PENGARUH PENGUNGKAPAN SUSTAINABILITY REPORT, KINERJA LINGKUNGAN, DAN STRUKTUR MODAL TERHADAP NILAI PERUSAHAAN DENGAN UKURAN PERUSAHAAN SEBAGAI VARIABEL MODERASI
Authors: Sevnia Resa , Susi Dwi Mulyani
Published: October 2023

Penelitian ini bertujuan untuk menguji pengaruh pengungkapan sustainability report, kinerja lingkungan, dan struktur modal terhadap nilai perusahaan dengan ukuran perusahaan sebagai variabel moderasi. Jenis penelitian ini ialah penelitian kuantitatif dengan menggunakan data sekunder. Populasi dalam penelitian ini adalah perusahaan consumer non-cyclicals yang terdaftar di Bursa Efek Indonesia pada periode 2020-2022. Sampel dalam penelitian ini dipilih berdasarkan metode purposive sampling dan diperoleh 123 sampel. Penelitian ini menggunakan model analisis regresi moderasi. Hasil penelitian ini mengungkapkan bahwa pengungkapan sustainability report dan struktur modal berpengaruh positif terhadap nilai perusahaan, kinerja lingkungan tidak berpengaruh terhadap nilai perusahaan, dan ukuran perusahaan tidak mampu memoderasi pengaruh positif semua variabel independen terhadap nilai perusahaan.
PENGARUH PENGUNGKAPAN ENVIRONMENTAL, SOCIAL, DAN GOVERNANCE TERHADAP NILAI PERUSAHAAN
Authors: Christy Ega , Sofie
Published: October 2023

Penelitian ini dilakukan untuk menguji apakah pengungkapan Environmental, Social, dan Governance (ESG) perusahaan memiliki pengaruh yang terhadap nilai perusahaan yang diproksikan dengan Tobin’s Q. Penelitian ini merupakan penelitian kuantitatif yang menggunakan purposive sampling sebagai teknik pengumpulan sampelnya. Perusahaan-perusahaan yang terdaftar dalam Indeks SMInfra18 menjadi sampel penelitian ini. Lebih lanjut, penelitian ini menggunakan standar GRI sebagai dasar pengukuran pengungkapan ESG. Hasil penelitian menunjukkan bahwa pengungkapan Environmental dan Social yang dilakukan perusahaan tidak memiliki pengaruh yang positif dan siginifikan terhadap nilai perusahaan. Sedangkan pengungkapan Governance terbukti memiliki pengaruh yang positif dan signifikan terhadap nilai perusahaan. Penemuan ini mengindikasikan diperlukannya peningkatan penerapan ESG dan kualitas pengungkapan ESG pada perusahaan yang terdaftar pada SMInfra18 Index dalam rangka mewujudkan tujuan pembangunan berkelanjutan dan peningkatan nilai perusahaan.
PENGARUH KEPEMILIKAN SAHAM MAYORITAS, KEPEMILIKAN MANAJERIAL, KOMITE AUDIT, KOMISARIS INDEPENDEN, ENVIRONMENTAL PERFORMANCES, DAN MODAL INTELEKTUAL TERHADAP KINERJA KEUANGAN
Authors: Elshadeiana  , Sekar Mayangsari
Published: October 2023

Penelitian ini bertujuan untuk menguji pengaruh Kepemilikan Saham Mayoritas, Kepemilikan Manajerial, Komite Audit, Komisaris Independen, Environmental Performances, dan Modal Intelektual terhadap Kinerja Keuangan pada perusahaan sektor consumer non cyclicals, consumer cyclicals, dan basic materials yang terdaftarkan di Bursa Efek Indonesia tahun 2017-2021. Metode untuk penghimpunan data pada studi ini yaitu mempergunakan data sekunder yang berasal dari laporan tahunan dan laporan keuangan sektor consumer non cyclicals, consumer cyclicals, dan basic materials yang tercantum pada Bursa Efek Indonesia (BEI) periode 2017-2021. Teknik pengambilan sampel dalam studi ini adalah teknik purposive sampling dengan total sampel 79 perusahaan. Penelitian ini mempergunakan metode analisis regresi data panel mempergunakan aplikasi Eviews 9. Sebagaimana hasil pengujian, variabel kepemilikan saham mayoritas, kepemilikan manajerial, komite audit, komisaris independen, dan modal intelektual berpengaruh positif kepada kinerja keuangan. Sementara, variabel environmental performances tidak berpengaruh kepada kinerja keuangan.
The Typewriter’s Tale: Re-Exploring the Historical Figure of Henry James through Fiction
Authors: Breytenbach Albertus
Published: October 2023

This article investigates the relationship between historical fiction, history, and the portrayal of the character and identity of Henry James with specific reference to The Typewriter’s Tale (2005) by Michiel Heyns. Furthermore, it explores how Heyns proceeds to strike a historically responsible balance in his portrayal of the identities of Henry James, Morton Fullerton and Edith Wharton as characters in the novel and the identities of these personae as historical figures. It also explores how Heyns imaginatively bridges the gaps in the historical record or relies on creative licence to reinterpret events and characters. Lastly, the contribution that historical fiction can make to our understanding of the identity and character of historical figures is considered.
Tendência da incidência de câncer colorretal em Belém e Ananindeua, Pará
Authors: Costa Nataly Yuri , Alencar Folve Ariel Garcia , Costa Thiago Simplicio , Costa Marta Solange Camarinha Ramos , Santos Luciana Ferreira dos , Formigosa Lucrecia Aline Cabral
Published: October 2023

Objetivo: Analisar a tendência temporal de incidência por câncer colorretal nos municípios de Belém e Ananindeua, no período de 2008 a 2017. Métodos: Estudo ecológico de séries temporais, incluindo diagnóstico por câncer em cólon, junção retossigmoide, reto, ânus e canal anal. A análise descritiva foi feita segundo sexo, faixa etária, anos de diagnóstico e topografia. Para análise de tendência foi usado o Programa Joinpoint Trend Analysis e calculada a Variação Percentual Anual, considerando estatisticamente significativa quando p <0,05. Resultados: Em ambos os sexos, as topografias com significância estatística foram os casos diagnosticados na faixa etária >64 anos. Na análise da tendência temporal por faixa etária, estratificada por sexo, observou-se que em ambos os sexos as faixas etárias 20 a 44 e 44 a 64 não apresentaram variação relevante ao longo dos anos. Conclusão: A incidência dessa doença reflete um problema de saúde pública, que enfatiza a necessidade de programas e políticas de prevenção, rastreamento, diagnóstico e tratamento precoce, contribuindo para o panorama epidemiológico do câncer no Brasil.
Avaliação do conhecimento da população acerca do câncer de pele
Authors: Paiva Melina Pereira Fernandes , Andrade Junior Luiz de Alencar , Lemos Luiza Alcântara Pontes de , Rodrigues Maria Eduarda Gomes , Costa Joanne Elizabeth Ferraz da , Duarte Iasmin Nunes , Ricardo Raphaela Martinelli , Azevedo Julia de Camillis , Borba Edna Silvia Pereira , Brito Esther Bastos Palitot de
Published: October 2023

Objetivo: Compreender o conhecimento da população sobre o câncer de pele e sua relação com a exposição solar, identificando os fatores que influenciam esse conhecimento. Métodos: Estudo transversal, quantitativo e observacional com pacientes que participaram da campanha nacional de prevenção ao câncer de pele realizada em um hospital do estado da Paraíba. Aplicou-se questionários compostos por itens de caracterização fenotípica, conhecimentos sobre o tema e opinião acerca da campanha. Após isso, realizou-se a análise estatística dos dados. Resultados: Observou-se maior predomínio de indivíduos do sexo feminino, idosos e de fototipos baixos. O percentual de pacientes que afirmaram possuir conhecimento prévio acerca do câncer de pele foi de 88,9%. Constatou-se ainda a presença de relação estatisticamente significativa entre as variáveis estudadas. Além disso, observou-se que os homens fazem menos uso de filtro solar e os idosos apresentaram menor grau de conhecimento sobre o tema. Conclusão: Considerando os dados do artigo, destaca-se a importância de captar o conhecimento da população sobre exposição solar e medidas de proteção. Espera-se que este estudo seja um subsídio importante para ações de saúde pública voltadas à prevenção do câncer de pele na cidade de João Pessoa, sobretudo homens e idosos.
Endovascular glue embolization of the medial posterior choroidal artery aneurysm: A case report and a literature review
Authors: Jha Vikas Chandra , Alam Mohammad Shahnawaz , Sinha Vivek Sharan , Verma Gaurav , Kumar Nitish , Jain Rahul
Published: October 2023

Background:

The medial posterior choroidal artery (MPCA) aneurysm is extremely uncommon. Thus yet, just a few cases have been reported. Due to the deep position, narrow lumen, fragile walls, and extensive tortuosity, both endovascular and microsurgical procedures are strictly limited. A case study of successful endovascular glue embolization of a left MPCA aneurysm and a literature review is included in this report.

Case Description:

A 17-year-old female arrived at our institution 2 days after suffering a major intraventricular hemorrhage with a minor subarachnoid hemorrhage. Digital subtraction angiography revealed a left MPCA aneurysm. The patient underwent a successful endovascular glue embolization and had a favorable functional outcome.

Conclusion:

Endovascular glue embolization yielded favorable clinical and angiographic results in MPCA aneurysms where microcatheter access and maneuverability are challenging.
Utility of sodium fluorescein in recurrent cervical vagus schwannoma surgery
Authors: Marrone Salvatore , Sanz Julio Alberto Andres , Cacciotti Guglielmo , Campione Alberto , Boccacci Fabio , Fraschetti Flavia , Iacopino Domenico Gerardo , Mastronardi Luciano
Published: October 2023

Background:

Cervical schwannoma is a rare neoplasm that usually occurs like a nondolent lateral neck mass but when growing and symptomatic requires radical excision. Sodium fluorescein (SF) is a dye that is uptake by schwannomas, which makes it amenable for its use in the resection of difficult or recurrent cases.

Methods:

We describe the case of a patient presenting with a recurrence of a vagus nerve schwannoma in the cervical region and the step-by-step technique for its complete microsurgical exeresis helped by the use of SF dye.

Results:

We achieved a complete microsurgical exeresis, despite the presence of exuberant perilesional fibrosis, by exploiting the ability of SF to stain the schwannoma and nearby tissues. That happens due to altered vascular permeability, allowing us to better differentiate the lesion boundaries and reactive scar tissue under microscope visualization (YELLOW 560 nm filter).

Conclusion:

Recurrent cervical schwannoma might represent a surgical challenge due to its relation to the nerve, main cervical vessels, and the scar tissue encompassing the lesion. Although SF can cross both blood–brain and blood–tumor barriers, the impregnation of neoplastic tissue is still greater than that of nonneoplastic peripheric tissues. Such behavior may facilitate a safer removal of this kind of lesion while respecting contiguous anatomical structures.
Retinocytoma malignancy
Authors: Yarovoy A.A. , Kotelnikova A.V. , Galbatsova A.G. , Matyaeva A.D.
Published: October 2023

In this article we described a clinical case where benign tumor retinocytoma were transformed into malignant tumor retinoblastoma. This work reflects the clinical picture and diagnostic methods necessary for making a clinical diagnosis. Considering the possibility of retinocytoma malignant transformation, patients should be under lifelong supervision. Key words: retinocytoma, retinoblastoma, protein p27, nonsense mutation, benign tumors in children, malignancy
Improving the sustainability of enzymatic synthesis of poly(butylene adipate)-based copolyesters. Polycondensation reaction in bulk vs in diphenyl ether
Authors: Sokołowska Martyna , Molnar Kristof , Puskas Judit E. , El Fray Miroslawa
Published: October 2023

In response to mounting global concerns such as CO2 emissions, environmental pollution, and the depletion of fossil resources, the field of polymer science is shifting its focus toward sustainability. This research investigates the synthesis of poly(butylene adipate)-co-(dilinoleic adipate) (PBA-DLA) copolymers using two distinct methods: bulk polycondensation and polycondensation in diphenyl ether. The objective is to assess the environmental impact, chemical structure, composition, and key properties of the resulting copolymers, with a particular emphasis on determining the viability of bulk synthesis as a more sustainable approach. Various analytical methods, including nuclear magnetic resonance spectroscopy (NMR), Fourier transform infrared spectroscopy (FTIR), and size exclusion chromatography (SEC), were employed to confirm successful copolymerization and highlight differences in molecular weight and microstructure. Additionally, thermal and dynamic mechanical analyses were conducted to thoroughly characterize the copolymers' properties. This research provides significant findings into the sustainable production of PBA-DLA copolymers, offering a more environmentally friendly approach without compromising product quality or performance.
Towards Accurate Quantum Mechanical Thermochemistry: (1) Extensible Implementation and Comparison of Bond Additivity Corrections and Isodesmic Reactions
Authors: Payne A. Mark , Wu Haoyang , Pang Hao-Wei , Grambow Colin A. , Ranasinghe Duminda S. , Dong Xiaorui , Dana Alon Grinberg , Green William H.
Published: October 2023

To obtain accurate enthalpies of formation of a chemical species, Hf, one needs a procedure to quantitatively connect the results from quantum mechanical (QM) calculations with the experimental enthalpies of elements in their standard state, often along with additional empirical corrections. Although QM methods continue to improve, accuracy gains from new methods are usually realized if the calculations for Hf are properly corrected. One such approach is to use atomization energy corrections (AECs) followed by bond additivity corrections (BACs), such as those defined by Petersson et al. or Anantharaman and Melius. Another approach is to utilize isodesmic reactions (IDRs) which are error-canceling reactions that can be constructed systematically as shown by Buerger et al. In this work, we implement all of these approaches in Arkane, an open-source software that can calculate species thermochemistry from computations done by a wide variety of QM software packages. As part of this work, we curate a diverse database of over 400 reference species from the available literature for use in fitting BACs or to participate in IDRs, and also provide AECs and BACs for 15 commonly used levels of theory using the workflow implemented. When comparing the approaches, we find that both BAC types yield results of similar accuracy, though the Anantharaman and Melius-type BACs seem to generalize better. Further, although the IDRs approach is often as accurate as the BAC approaches and sometimes even more advantageous, we find that this method appears to be less robust than the BAC methods. In particular, the accuracy of the IDRs approach is sensitive to the chosen reference species and reactions. Therefore, in addition to providing the automated AECs and BACs fitting procedure, we also propose improved methods to select IDRs.
Charge transfer in superbase n-type doping of PCBM induced by deprotonation
Authors: Dong Chuanding , Bauch Fabian , Hu Yuanyuan , Schumacher Stefan
Published: October 2023

N-type electronic doping of organic semiconductors (OSCs) by using superbase compounds shows high doping efficiency (Adv. Mater. 2023, 35, 2300084). While a deprotonation reaction is believed to trigger the doping process, the detailed mechanism therein is not yet fully understood. In the present work we theoretically study the electronic structure of the deprotonated Phenyl-C61-butyric acid methyl ester (PCBM) molecule, as well as the charge transfer (CT) between PCBM and its deprotonated species. We find that deprotonated PCBM without formation of a new bond between the deprotonated side chain and fullerene induces electronic structure with broken spin symmetry, where an in-gap state is singly occupied by an unpaired electron. A second scenario that we find to be possible is the formation of a new bond between the deprotonated side chain and a fullerene. This leads to a spin symmetric electronic structure with partially localized in-gap state, which is expected to contribute less to the effective doping. These results show that the deprotonated PCBM species without new bond formation predominantly accounts for the effective n-type doping of PCBM, an insight that will be useful for optimization of this recently discovered doping method.
Main Proteases of Key RNA Viruses, Including Coronavirus, Recognize P2 Residues in the Polyproline Type II Conformation: Harnessing Proline's Unique Conformation for Protease Inhibitors
Authors: Weerawarna Pathum
Published: October 2023

Positive-sense RNA viruses, particularly those in the Picornavirus-like superfamily and the Coronaviridae family, significantly impact public health, necessitating the development of focused antiviral agents. The main proteases of these viruses are promising targets for antiviral development. Peptidyl protease inhibitors containing Pro derivatives, mimicking rigid Leu at the P2 position, have emerged as potent drug candidates against SARS-CoV-2 3CLpro, despite several theoretical disadvantages compared to non-Pro rigid Leu mimetics: loss of a critical hydrogen bond due to the Pro tertiary amide and the unique PPII conformation associated with Pro, contrasting the protease-preferred β-strand conformation in the solution phase. Interestingly, despite these potential drawbacks, Pro derivatives that mimic a rigid Leu at the P2 position manage to either enhance or maintain inhibitory activities when compared to non-Pro derivatives. In this study, we analyzed over 200 crystal structures of main protease-bound peptidyl inhibitors of major RNA viruses. Our analysis revealed a previously unnoticed preference of these main proteases for the P2 residues of peptidyl inhibitors to adopt the PPII conformation, contrasting the traditional β-strand conformation. Furthermore, our unbiased all-atom classical MD simulations of literature examples confirm that using Pro-based rigid Leu mimetics constrains the P2 residue to the enzyme-preferred PPII conformation in the solution phase. This leads to a significant reduction in configurational entropy, comparable in magnitude to a typical strong hydrogen bonding interaction when compared to non-Pro P2 residues. Despite the loss of a critical hydrogen bond, this phenomenon accounts for the enhanced binding affinities of peptidyl protease inhibitors that feature Pro-based rigid Leu mimetics as the P2 residue. These findings provide new insights into the binding dynamics of peptidyl protease inhibitors with viral main proteases and highlight the importance of new strategies to constrain the P2 residue of peptidyl inhibitors in the PPII conformation, without sacrificing the P2 amide hydrogen, which will further enhance the binding affinities.
Borylated Cyclopentanes via Atom Transfer Radical [3+2] Annulation
Authors: Cirule Dace , Dénès Fabrice , Gnägi-Lux Manuel , Rohrbach Simon , Renaud Philippe
Published: October 2023

Abstract. An atom transfer radical [3+2] annulation (ATRAn) reaction involving alkenyl boronic esters and homoallylic iodides provides a rapid access to polysubstituted borylated cyclopentanes. A variety of α-substituted vinylboronic esters are suitable substrates and offer unique opportunities for further modification of the formed 5-membered ring. For instance, the oxidation of the boronic ester to an alcohol allows to prepare products that corresponds to an annulation involving the enol form of acetone. Substitution of the iodide by a nucleophile such as lithium methoxide without modifying the boronic ester moiety is also feasible. Finally, by using a (3-acetoxyprop-1-en-2-yl)boronic ester, a facile 1,2-elimination reaction provided a methylenecyclopentane. In this case, the alkenylboronate radical trap acts as an equivalent to allene, a building block so far elusive for preparative radical reactions.
Post-synthetic Covalent Grafting of Amines to NH2-MOF for Post-Combustion Carbon Capture
Authors: JUSTIN ANITA , Espín Jordi , Pougin Miriam , Stoian Dragos , Schertenleib Till , Mensi Mounir , Kochetygov Ilia , Ortega-Guerrero Andres , Queen Wendy L.
Published: October 2023

Herein, we report a post-synthetic modification strategy to covalently graft polyamines, including ethylenediamine (ED), diethylenetriamine (DETA), tris(2-aminoethyl)amine (TAEA), and polyethyleneimine (PEI) to the amino-ligand of a Cr-MOF, NH2-Cr-BDC, for post-combustion carbon capture applications. X-ray absorption spectroscopy (XAS) and X-ray photoelectron spectroscopy (XPS) reveal that ~45% of the MOF ligands are grafted with polyamines. Also, after assessment of CO2 uptake, CO2/N2 selectivity, isosteric heats of CO2 adsorption, separation performance during humid CO2/N2 (15/85) breakthrough experiments, and cyclability, the study reveals an enhanced performance for the polyamine composites and the following performance trend: NH2-Cr-BDC
Diagnostics of Regions Resource Potential in the Context of Socio-Economic Development
Authors: Zaytsev Andrey , Dmitriev Nikolay , Kichigin Oleg
Published: October 2023

Purpose: The purpose of the study is to study the possibilities for diagnosing the resource potential of the regions, taking into account the indicators of their socio-economic development.
 
Theoretical framework: To conduct the study, the indicators characterizing the socio-economic development of the regions were analyzed; Based on the selected indicators, indices of sub-potentials and integral estimates of the resource potential of the regions were calculated.
 
Design/methodology/approach: The diagnostics of the resource potential of the regions is carried out by means of an integral assessment of sub-potentials through an indicative analysis, where the average values for the country are the standard. The obtained indicative estimates (indices) for the sub-potentials of the resource potential make it possible to identify rent-forming conditions in the regions. It is proposed to use a “simplified” diagnostic model for the study, which contains the main indicators for analysis; in the "enlarged" model, it is planned to use an expanded range of indicators to identify dependencies, taking into account their dynamic changes. Approbation was carried out in the Russian region - Novgorod region.
 
Findings: As a result of the study, indicative estimates (indices) of the subpotentials of the resource potential of the analyzed regions were obtained, and their integral estimates of the resource potential were determined. The diagnostics of the resource potential made it possible to rank the regions according to the factor conditions of socio-economic development, as well as to lay the basis for assessing the effectiveness of the use of regional resource opportunities.
 
Research, Practical & Social implications: The study expands scientific knowledge in the field of formation and use of the resource potential of the regions. Improving the assessment system within the proposed approach for conducting diagnostics for specific regional tasks will allow for a competent regional policy with a focus on the strengths and weaknesses of the socio-economic development of the region.
 
Originality/value: The value of the study lies in the ranking of regions depending on resource conditions, which can help determine rent-forming factors and build an assessment of the efficiency of using resource potential.
Well-being and Life Satisfaction of Strength Athletes During War: Role of Individual and Health-Related Determinants
Authors:   Lviv State University of Physical Culture, Lviv, Ukraine, Pavlova Iuliia ,   Lesya Ukrainka Volyn National University, Lutsk, Ukraine, Roztorhui Mariia ,   Lviv State University of Physical Culture, Lviv, Ukraine, Petrytsa Petro ,   Ternopil Volodymyr Hnatiuk National Pedagogical University, Ternopil, Ukraine, Melnyk Tetiana ,   Kamyanets-Podilskyi Ivan Ohiienko State University, Kamyanets-Podilskyi, Ukraine, Nalyvayko Natalia ,   Kamyanets-Podilskyi Ivan Ohiienko State University, Kamyanets-Podilskyi, Ukraine, Ohnystyi Andrii ,   Ternopil Volodymyr Hnatiuk National Pedagogical University, Ternopil, Ukraine
Published: October 2023

The research aims to identify the determinants of well-being of youth strength athletes taking into account individual parameters (level of stress, anxiety, depression) and contextual parameters (change of place of residence, change of opportunity to train due to war), differences compared to an older age group. The online study was performed on elite strength athletes (N=172) in Ukraine during Russo-Ukrainian war. In addition to demographic characteristics, the survey included question to sports activity, issues related to hostilities, standardized questionnaires to measure life satisfaction (SWLS), perceived stress level (PSS-10), depression (PHQ-9), anxiety (GAD-7), physical, mental and social functioning (SF-36). Statistical analysis included descriptive statistics, correlation analysis to find association between variables, and building linear regression models. Samples of young and adult athletes that we analyzed did not differ in terms of life satisfaction. Among young athletes there were significantly fewer people with symptoms of stress (67%) and anxiety (25.53%). Three groups of factors that determine the life satisfaction of young Ukrainian athletes can be single out: individual (stress, depression), contextual (change of place of residence or training due to the war), and health-based (general perception of one’s own health and pain sensations). The data highlight the critical importance of mental health monitoring for the overall well-being of athletes. The obtained results can be used to rapidly screen persons in the risk group during a war and further develop individual psychotherapeutic programs to overcome trauma and the consequences of war.
Evaluation of Different Equations for Resting Metabolic Rate Prediction in Female Combat Sports Athletes
Authors:   Faculty of Sport Sciences, Coaching Training Department, Trabzon University, Trabzon, Turkey, Tortu Erkan , Birol Abdulkadir ,   Faculty of Sport Sciences, Coaching Training Department, Trabzon University, Trabzon, Turkey, Aksarı Meryem ,   Faculty of Sport Sciences, Coaching Training Department, Trabzon University, Trabzon, Turkey
Published: October 2023

Only a few studies have produced equations that can estimate resting metabolic rate (RMR) in female athletes, but the accuracy of these equations for combat athletes has not yet been tested. The aim of this study was to evaluate the 12 different equations which are commonly using to determine resting metabolite rate (RMR) in the literature. Twenty-three female combat sport athletes (24.23± 3.39 years; 166.8 ± 5.3 cm; 63.13±6.53 kg; 8.78±3.19 experience years.; 56.40±3.43 VO2 mL/kg/min) were participated this study in voluntarily basis. A cross-validation approach used to compare the accuracy of 12 commonly prediction equations with measured RMR by indirect calorimetry to determine RMR in female combat sports athletes. All the predictive equation was underestimated RMR when compared with the measured RMR (p < 0.05) and the smallest mean difference (92.46 ± 210.38 kcal·d-1) was observed for Altman & Dittmer equation amongst the 12 predictive equations. The Altman & Dittmer equation was accurately predicted 16 out of 30 subjects’ RMR value within the range ±10%. However, based on the Bland–Altman plots, the prediction equations were not accurately nor precisely predicted RMR in the current sample of female combat sport athletes. The results in the present study showed that the Altman & Dittmer equation is most suitable equation to predict RMR amongst 12 equations. Although the Altman & Dittmer equation was resulted with smallest mean difference, it seems that there is need to further research with longitudinal approach to understand the effects of training intensity and body mass changes on RMR in order to develop the formulas already exist used commonly.
Assessment of Aerobic Fitness and Body Mass Index of Officers of the Nigerian Police Force in Enugu State, South East Nigeria
Authors:   University of Nigeria, Human Kinetics and Health Education Department, Nsukka, Enugu State, Nigeria, Kingsley Oforka Okechukwu , Emeka Umeifekwem Joshua ,   University of Nigeria, Human Kinetics and Health Education Department, Nsukka, Enugu State, Nigeria, Emmanuel Iwuagwu Tochi ,   University of Nigeria, Human Kinetics and Health Education Department, Nsukka, Enugu State, Nigeria, Aaron Umeakuka Okey ,   University of Nigeria, Human Kinetics and Health Education Department, Nsukka, Enugu State, Nigeria, Chinyere Ofili Perpetua ,   University of Nigeria, Human Kinetics and Health Education Department, Nsukka, Enugu State, Nigeria, Jinedu Badaru Umar ,   University of Nigeria, Human Kinetics and Health Education Department, Nsukka, Enugu State, Nigeria
Published: October 2023

This study assessed the aerobic fitness and body mass index of officers of the Nigerian Police Force in Enugu State, Nigeria. It was a cross-sectional study and a total number of 343 police officers participated. Aerobic fitness was evaluated with a 20-metre shuttle run also known as Progressive Aerobic Cardiovascular Run (PACER) test which was used to estimate maximal oxygen uptake (VO2max) of participants. Body Mass Index (BMI) was also measured and a proforma was used to record PACER performance, gender, age and years of service. Mean, Standard Deviation and Linear regression were used for analyses. The Statistical Package for the Social Sciences (SPSS) version 25 was used for the data analysis. The findings revealed that the police officers had a mean VO2max of 46.01±8.644 ml/kg -1 ·minute -1. The police officers had a mean BMI of 25.68kg/m2, which was significantly associated (<0.001) with their VO2max. The study concluded that higher BMI is associated with decrease in VO2max. Gender had a significant relationship with the BMI of police officers, as female officers had higher BMI while male officers had lower BMI. Age had a significant relationship with the BMI of police officers, as their higher age is associated with their higher BMI. However, officers of both genders particularly females need to engage more in physical activities to have improved aerobic capacity and have their BMI within a healthy range.
The damages of processus vermicularis and Meckel’s diverticulum in gun–shoot abdominal woundings
Authors: Lurin I. A. , Khoroshun E. M. , Vorovsky O. O. , Nehoduiko V. V. , Makarov V. V. , Panasenko S. I. , Gumenuk K. V. , Ossovskyi O. V. , Yakymova T. P. , Saliutin R. V.
Published: October 2023

Objective. Determination of the damages peculiarities in processus vermicularis and Meckel’s diverticulum in a gun–shot abdominal woundings and tactics of their surgical treatment.

Materials and methods. Analysis of the gun–shot abdominal woundings has been witnessed the presence of isolated and combined damages of processus vermicularis and Meckel’s diverticulum in 0.18 and 0.06% patients, accordingly. All the wounded persons were the men, their average age have constituted (32±0.3) yrs old. The shrapnel woundings have occurred in 92.4% patients, and the bullet – in 7.6%. Damages of the processus vermicularis base have dominated in its descendent localization, the damages of processus vermicularis and Meckel’s diverticulum were combined with such intestinal affections.

Results. All the damages of Meckel’s diverticulum and processus vermicularis were revealed intraoperatively. All the hospitalized patients have had the pain syndrome, the peritonitis signs and free liquid in a small pelvis. Surgical tactics consisted of resection of processus vermicularis (in 2 patients using laparoscopic approach), and in the Meckel’s diverticulum woundings the operative intervention volume have included a wedge–like resection of the small intestine part with diverticulum or segmental intestinal resection with formation of the side to side ileo–ileoanastomosis.

Conclusion. The damages of processus vermicularis and Meckel’s diverticulum constitute a rare combat woundings, which occurs in combined intestinal trauma, what constitute the need for its detailed intraoperative revision. Operative tactics in damages of processus vermicularis and Meckel’s diverticulum constitutes their resection and restoration of intestinal integrity and may be realized through laparoscopic access.
First experience of exploitation of extracorporeal shock–wave therapy for treatment of chronic posttraumatic osteomyelitis
Authors: Hertsen H. I. , Remenyuk Yu. K. , Bilonizhkin G. G. , Sikorska M. V. , Volk F. O.
Published: October 2023

First experience of exploitation of extracorporeal shock–wave therapy for treatment of chronic posttraumatic osteomyelitis
Colorectal cancer with synchronous liver metastases: terminology, diagnosis and management
Authors: Usenko O. Yu. , Skums A. A.
Published: October 2023

Colorectal cancer with synchronous liver metastases: terminology, diagnosis and management