bluuebunny/crossref_metadata_2025 huggingface dataset:
Mutlak Gelir ve Yaşam Memnuniyeti: Nispi Gelir ve Sosyal Referans Gelir Etkisinin Aracılık Rolü
Authors: GÜL Songül
Published: October 2023

Yaşam memnuniyetinin en önemli belirleyicilerinden biri mutlak gelirdir. Gelirin yaşam memnuniyeti üzerindeki etkisi alanda en çok tartışılan konulardan biridir. Yaşam memnuniyetinin belirleyicileri üzerinde yapılan çalışmalarda göçmenler sahip oldukları farklı dinamikler nedeniyle özel bir konuma sahiptir. Bu çalışmada Türkiye’de yaşayan göçmenlerin mutlak gelirleri ile yaşam memnuniyeti arasındaki ilişkide nispi gelir ve sosyal referans gelir etkisinin rolü Hayes aracılık analizi ile test edilmiştir. Çalışmada yedi farklı yaşam alanı referans gurubu kullanılmıştır. Araştırmaya toplamda 1505 kişi katılmış ve bu katılımcıların 717’si kadın 788’i erkektir. Elde edilen sonuçlara göre mutlak gelir ile yaşam memnuniyeti arasında anlamlı fakat negatif yönlü bir ilişki mevcuttur. Nispi gelir ve sosyal referans gelir etkisi ile yaşam memnuniyeti arasında ise anlamlı, pozitif yönlü ve oldukça kuvvetli bir ilişki mevcuttur. Çalışmada nispi gelir ve sosyal referans gelir etkisinin mutlak gelir ve yaşam memnuniyeti arasındaki ilişkide kısmi aracılık rolü olduğu tespit edilmiştir. Aracı değişkenlerin analize dahil edilmesi ile mutlak gelir ile yaşam memnuniyeti arasındaki negatif yönlü ilişkinin gücünün azaldığı görülmektedir.
John Maynard Keynes’in İstihdam Faiz ve Paranın Genel Teorisi’nin Türkçe Serüveni
Authors: VURAL Abdurrahman Gazi
Published: October 2023

John Maynard Keynes’in düşüncesinin Türkiye’ye girişi ve anlaşılması oldukça gecikmeli olmuştur. Özellikle onun başyapıtı Genel Teori 1936 yılında İngilizce yayınlanmasından tam 23 yıl sonra Türkçeye çevrilmiştir ve bu çeviri kitap olarak yayınlanmadığı gibi tam bir çeviri değildir. Daha sonra yapılmış çeviri denemeleri ne yazık ki Genel Teori’nin büyüklüğüne uygun yeterlilikte olmamıştır. Hatalı ve özensiz çeviri, kitabın Türkçe okunmasını imkansızlaştırdığı gibi Keynes’in düşüncesinin yanlış anlaşılmasına yol açabilmektedir.

Bu çalışma, Genel Teori’nin Türkçe serüveni bağlamında Türk iktisadı düşünce tarihine küçük bir katkıda bulunmayı amaçlamaktadır.
Parlamenterler Bürokratları Nasıl Anıyor? TBMM’nin 27. Yasama Dönemi Üzerine Bir İçerik Analizi
Authors: AYDIN Recep
Published: October 2023

Bürokrasi ve bürokrat kavramları Türk kamu yönetimi ve siyasal hayatında önemli kavramlar olagelmiştir. Osmanlı idari modernleşmesinden kalkınmaya kadar pek çok alanda kullanılan kavram, gündelik siyasal ve yönetsel tartışmalarda da karşımıza çıkmaktadır; yeni hükümet sisteminde seçilmiş ve atanmışlar arasındaki ilişkiler açısından da ilginç konuların başında gelmektedir. Araştırma, tam da bu iki kesim arasındaki ilişkiyi, seçilmişler gözüyle ele almak üzere tasarlanmıştır. Çalışmanın konusu 27. yasama döneminde parlamento tartışmalarında parlamenterlerin bürokratların nasıl anıldıklarıdır. Parlamenterler bürokrat kavramına nasıl bir anlam yüklemektedir? Türkiye Büyük Millet Meclisi (TBMM) çatısı altında 27. yasama dönemi içerisinde, bürokrat kavramının kullanılış biçim ve içeriğine odaklanan çalışma nitel içerik çözümlemesi yaparak TBMM’de bürokrat kavramının nasıl bir içerikle kullanıldığını ortaya çıkarmayı amaçlamaktadır. Bu yapılırken çalışma 27. dönem, yani yeni hükümet sisteminde denk düşen 2018 seçimlerinden çalışmanın verilerinin son bulduğu oturumu kapsayacak şekilde sınırlandırılmış; ilgili aralıkta bürokrat kavramının ilk kullanıldığı gün olan 17.07.2018’den 17.01.2023’e kadarki dönem incelenerek bir veri seti oluşturulmuştur. Böylelikle yeni hükümet sisteminde TBMM’nin bürokrat kavramını hangi bağlam ve içerikle tartıştığı, değerlendirici kategoriler tespit edilerek incelenmiştir. Kavramın, birincil anlamıyla kullanılışı yaygın olmakla beraber konjonktüre bağlı olarak olumsuz içerikle kullanılışının daha sık olduğu görülmektedir. Bürokrat kavramının geçtiği oturumlarda kavram 315 kez kullanılırken bunların 156’sı olumsuzdur. Özellikle muhalefet partilerinin, bürokrat kavramını ağırlıkla partizanlık, kayırmacılık ve yolsuzluk ile ilişkilendirerek ve olumsuz manada kullandığı anlaşılmıştır. İktidar ortakları ise kavramı en çok sözlük anlamıyla, nötr bir içerikle kullanmıştır. TBMM tartışmalarında bürokrat kavramının yeni hükümet sistemiyle siyaseten merkeze daha bağlı bürokratları karşılamak üzere ve yer yer bir tür itibar kaybına uğrayarak kullanıldığı ortaya çıkmıştır.
Bir Girişimci “Burjuva” Olarak “Bay Peachum” ya da Sombart vs. Brecht
Authors: SERT Mesut
Published: October 2023

İktisadi düşünce tarihi içinde pek de iyi olmayan bir akademik ve kişisel şöhrete sahip olan Sombart ile epik tiyatronun öncüsü sayılan Brecht’in burjuva/girişimciyi ele alış biçimleri açısından karşılaştırma amacında olan bu çalışmada her iki yazarın bu kapsamda temel metni olarak değerlendirilebilecek Burjuva ve Beş Paralık Roman’daki burjuva/girişimci anlatıları derlenerek aralarındaki benzerlik ve farklılıklar üzerinde durulmuştur. Sombart, kapitalizme yol açan yeni bir insan tipi olarak burjuvanın sahip olduğu niteliklerin tarihsel seyrini iki dönem şeklinde resmederken; Brecht, savaş sonrası dönemin burjuva/girişimcisi ve gerçekte kapitalizmine yönelik bir başka hikâye anlatır. Her iki eserin incelemesi sonucunda iki anlatı arasındaki temel farklılığın Sombart’ın kapitalizmin ileri aşamalarına ait olduğunu söylediği ve erken dönem burjuvasına özgü nitelikler ile kıyaslandığında negatif anlamlar yüklediği niteliklerin Brecht’te tüm dönemler için geçerli olan ve kapitalist girişimcinin gerçek doğasını yansıtır şeklinde ele alındığı söylenebilir.
İklim Krizi ve Ekolojik Bağlamda Devletin Rolünü Yeniden Düşünmek
Authors: ATVUR Senem , GÜNEŞ GÜLAL Asiye Gün , UYSAL OĞUZ Ceren
Published: October 2023

İklim değişikliğinin yıkıcı etkileri son yıllarda dünyanın her yerinde hissedilmekte ve sorun artık küresel bir krize dönüşmüştür. Bu süreçte uluslararası sistemin temel politik aktörü olarak kabul edilen egemen devletin ve devleti oluşturan nüfus ve toprak başta olmak üzere temel öğelerin kırılganlığı da artmaktadır. Bu çalışmanın amacı iklim krizinin yarattığı kırılganlıkları devletin sorumluluğu bağlamında incelemektir. Çalışma, iklim krizine karşı etkili mücadele için egemenlik ilkesinin ekosistemleri de içerecek şekilde genişletilmesi ve devletin ulusal ve uluslararası sorumlulukları yanında ulusötesi bağlamda ve adalet temelinde gezegensel sorumluluklarının geliştirilmesi gerektiğini öne sürmektedir. Çalışma iç içe geçen kırılganlıkları merkeze alarak iklim krizinin temelinde yatan nedenleri ve devletin bu süreçteki rolünü eleştirel bir bakış açısıyla ele almaktadır. Kırılganlıkları gidermek ve etkili azaltım ve uyum politikalarını uygulamak için daha adil, eşitlikçi ve sorumluluğu yaptırımla bağlayıcı hale gelecek bir devlete ihtiyaç vardır. Egemen devletlerin gezegendeki tüm yaşamı ve ekosistemleri de içeren yeni bir küresel rejim inşa edebilmesi devletin sorumluluğunun ulusal, uluslararası ve ulusötesi bağlamda yeniden kurgulanmasını da gerektirmektedir.
Post Factum: Transnasyonel Kapitalist Sınıf Üzerine
Authors: DOĞRU Mustafa Kemal
Published: October 2023

1980’lerin neoliberal dalgasının yayılması ve 1989’da sosyalist sistemin çözülmesinden sonra yaşanan küreselleşmenin bir transnasyonel kapitalist sınıfa yol açtığı ileri sürülmüştü. 1990’larda sosyal bilimlerin gündeminde ulus devletlerin zayıfladığını veya ortadan kalkmakta olduğunu ifade eden küreselcilik ideolojisi hâkim olmuştu. Bu ideolojinin bir varyantına göre, transnasyonel bir burjuva sınıfı ulus devletlerden kurtularak oluşmaktaydı. Daha da ötesi bazı yazarlara göre bu sınıf veya sınıf fraksiyonu kendine bir transnasyonel kapitalist devlet kurma arayışındaydı. Bazı yazarlara göre ise söz konusu transnasyonel devlet ABD’de cisimlenmişti. Ancak, 2008 ABD’de başlayan finansal kriz daha sonra 2011’de Avrupa ekonomilerine de yayıldı. Trump’un 2017’de ABD başkanı olmasıyla birlikte başlattığı ticaret savaşları ve resmen 2020’de gerçekleşen Brexit ile birlikte artık bir deglobalizasyon sürecinden söz edilmektedir. Jeopolitik bakımdan dünya giderek ABD-İngiltere - AB ve Doğu Asya’daki müttefikleri ile Çin -Rusya ve müttefikleri arasında bölünmeye başladı. Nihayet 2022 yılında başlayan ve halen devam eden Rusya-Ukrayna savaşı hegemonya mücadelesini şiddetlendirdi. Bugünlerde netleştiği üzere liberal dünya düzeni yerini hızla milliyetçi bir dünyaya bırakmaktadır. Böylelikle, transnasyonel kapitalist sınıf oluşumu ampirik düzeyde doğrulanamazken, çalışmamızda onun kapitalist devlet teorisi ve kapitalizmin temel yasası olan değer yasası bakımından da geçersiz olduğu hatırlatılmak istendi.
PENYULUHAN PANGAN BERPOTENSI GIZI UNTUK PENCEGAHAN STUNTING DI DUSUN TELAGA PANGE DESA RUMAHTIGA KOTA AMBON
Authors: Mutmainnah Heni , Rambe Nana Ronawan , Pary Corneli , Sahubauwa Laila , Renngiwur Janaba
Published: October 2023

Stunting is a condition of chronic malnutrition in children which can have an impact on children's motor and verbal development as well as affect their cognitive development and productivity in adulthood. The prevalence of stunting in Indonesia in 2021 is 24.4% and in Maluku the stunting rate is 28.70%. This figure is higher than the WHO threshold, which is 20%. The purpose of carrying out this PKM activity is to provide education regarding the dangers of stunting in children and efforts to prevent stunting through training in making nutritious food innovations for stunting prevention so that it can be a solution for people in the regions in improving their standard of living. The method used in this activity is lectures with slide media and the practice of making nutritious food for toddlers. The results of the socialization show that the community understands the dangers of stunting on the growth and development of children and the community is able to innovate nutritious foods for toddlers.
BIMBINGAN TEKNIS TENAGA KERJA KONSTRUKSI UNTUK PENGAWASAN BANGUNAN GEDUNG DAN MANDOR KONSTRUKSI
Authors: Ohorella Fuad Hasan , Amahekae Sammy G. M. , Latuconsina Syafrudin I. , Oppier Imran
Published: October 2023

The building is one of the human needs and is used as a place to live and do other activities, it consists of a combination of several materials and constructions to function as planned. Construction is part or all of the activities that include building construction, demolition, operation, and maintenance. One of the most essential processes in construction work is the issue of supervising construction work. As a unit in construction work, the supervisory position has two functions: monitoring and managerial. The training methods implemented in this activity are lecture, presentation, assignment, and discussion methods. Based on this, the Ministry of Public Works and Public Housing, Director General of Construction Development for Region VII Jayapura, collaborated with the Southeast Maluku Regency PUPR Service and Civil Engineering Study Program to carry out Bimtek activities with 32 participants. What was achieved in this activity by the participants was an increase in the knowledge and skills of supervision and construction work processes where the presenters found a significant increase in the participants when compared to the initial meeting
Potential Evapotranspiration in Merapi Aquifer System
Authors: Rahmawati Novi , Rahayu Kisworo , Arisanty Deasy
Published: October 2023

Temperature variation due to climate change can give greatest impact on potential evapotranspiration. Increase of temperature in Yogyakarta Special Region can increase potential evapotranspiration. It is necessary to study potential evapotranspiration as one of indication impact of climate change to its potential evapotranspiration. Potential evapotranspiration (PET) can be estimated applying Hargreaves and Samani (1982) that requires limited meteorological parameter. Therefore, this research aims are: a) to analyze daily PET in  3 gauge station of Merapi Aquifer System, b) to analyze variation PET in the 3 gauge stations of Merapi Aquifer System.

The largest values of PET is in Barongan station, while the lowest is in Adisucipto station. It is probably because Adisucipto station is located in urban and crowded areas. PET values are mostly 1.98 mm/day in rainy season, while 1.67 mm/day in dry season. Mostly, the correlation coefficient is low in dry season for Pluyon, Barongan and Adisucipto stations suggesting that drier and warmer temperature due to climate change do not have large impact to PET. The 5-month moving average trend also confirm the relatively stable line of PET variation from January 2005 to December 2016 reflecting that climate change do not greatly impact on PET in Merapi Aquifer System.
INFORMATION SYSTEM FOR ADMISSION OF STUDENT INTERNSHIP AT RRI MEDAN
Authors: Rindiani Rindiani , Devi Perwitasari Ika , Hendry Hendry
Published: October 2023

The Internship Acceptance Information System at RRI Medan is a platform designed to facilitate the process of accepting internship students at Radio Republik Indonesia (RRI) Medan. The purpose of this system is to increase efficiency and effectiveness in the process of accepting apprentice students and to strengthen the relationship between RRI Medan and the surrounding universities. This system offers several important features, including online registration, submission of files, and tracking of application status. Students who are interested in doing an internship at RRI Medan can access this system via a website or an easy-to-use mobile application. They can fill out the online registration form and upload the required files, such as CVs, grade transcripts, and letters of recommendation. After registration is complete, the system will process the application and provide notifications to students regarding the status of their application. Students can track the progress of their applications through this system, including information regarding interview schedules or other selection tests. If accepted, students will receive confirmation through this system and can continue with the internship preparation stage. This information system is built on a web basis.
Students’ Mathematical Beliefs At School That Separate Gender Based On Students’ Mathematical Autobiography
Authors: Kumala Dewi Fitri , Wulandari Tati , Sahanata Meirisa
Published: October 2023

This study aims to know the change in mathematical beliefs of students grade VII from elementary school until now in Junior High School through students’ mathematical autobiography.  The research design used in this study is qualitative descriptive. The data were obtained by using questionnaires and interviews. Instruments in this study are researchers as the main instrument, questionnaire about the identity of participants and 20 items of related statements about students' beliefs in mathematics, as well as interview guides as supporting instruments. The statement in the questionnaire is divided into 10 positive statements and 10 negative statements related to mathematics. The results of this study showed that firstly, almost all students, both male, and female, have a decline of beliefs in mathematics learning at the junior high school level. Second, the factors that affect the decreasing level of students' belief in mathematics during the junior high school are the drastic changes in the subject that becomes more difficult and more formulas to be memorized, and many lessons do not use concrete objects. Further, the teachers' attitudes who are also very different from when they are in elementary school which are more comfortable, their social conditions are changed because they live in dorms that have many activities (must be followed) that makes them busy so that they are difficult to find free time to learn outside the school hours. Third, students' beliefs about mathematics learning have shifted from positive to negative or vice versa.
Design of a Village Newspaper Application (Kordes) in Realizing a Digital Village in the Village of Dusun Baru V koto, Mukomuko Regency, Based on Android
Authors: Hendrawan Jodi , Devi Perwitasari Ika , Felawati Fatima
Published: October 2023

KorDes is a village newspaper application that contains the latest information that occurs in the village, information on village developments and information on village data as a form of realizing a digital village. This KorDes application was formed as a solution for the people of Dusun Baru V Koto Village, Mukomuko Regency who have difficulty in accessing valid and growing information in the village. In designing the KorDes application, it will be implemented based on Android. Android-based will make it easier for people to access via their smartphones which can be accessed at any time. The design of the application uses the technique of developing UML (unified modeling language) diagrams which makes it easier to document and define applications.
Design Of Web-Based Marketing And Ordering Applications At Talang Permai Store
Authors: Felawati Fatima , Sepriano Sepriano , Hendrawan Jodi , Zikri Afdalul
Published: October 2023

The development of computers is very rapid and the need for information is increasingly perceived existence in an organization, it is no wonder many agencies that use computers to support the operation of these agencies. The emergence of the Internet that increasingly facilitate the exchange of information between users. One of the internet activities in the business world is as a media marketing and product sales through a website. The existence of a website makes it easy for customers to access information about the sale of available building materials and ordering of building materials online for customers at Toko Talang Permai. During this time, the sale and purchase transactions are only done manually and all the information generated about building materials is also not always accurate. With the existence of a marketing and ordering website, it is hoped that Talang Permai Stores can provide the best service to its customers and help facilitate shop owners in terms of data processing. So that the resulting data is more accurate and can increase efficiency and effectiveness. The research methodology used is field research and library research. The design of the Talang Permai socialization and buying and selling media website was made using the PHP programming language and MySql database.
The Effect of Drug Users on Periodontal Health : Literature Review
Authors: Karyadi Edi , Abdul Kodir Ade Ismail , Zahiro Nadia Fairuz , Bouty Aulia Azizah Vidya
Published: October 2023

Background: Drug trafficking in the world affects the country and spread to all levels of Indonesian society. Methamphetamine, marijuana, and heroin are the most commonly abused drugs. Drugs cause a lot of bad effects, including the oral cavity. Results of Health Research on the Impact of Drug Abuse in 2019, as many as 64.1% of them experienced dental problems and 60.1% of oral cavity disorders. The risk of periodontal disease in drug users is higher than non-users. Objective: To determine the effect of the use of methamphetamine, marijuana, and heroin and the most influential drug users on the health of periodontal tissues. Methods: Using secondary data obtained through several e-databases, that are Pubmed Central (PMC), SpringerLink, and ResearchGate based on keywords and a predetermined time span. Discussion: Periodontal disease in drug users is related to xerostomia, oral hygiene, and immunosuppression. The high accumulation of calculus and plaque in drug users due to their low awareness of maintaining oral health and impaired motor function that makes it difficult for a person to clean his oral cavity. Comparison of Bleeding on Probing (BOP) and Clinical Attachment Loss (CAL) values were used as the main variables to show the parameters of periodontal tissue inflammation in each type of drug (methamphetamine, marijuana, and heroin). Conclusion: There was an effect of methamphetamine, marijuana, and heroin on the health of periodontal tissues including gingivitis and periodontitis. The heroin used by intravenous injection had the most effect on periodontal tissue health compared to methamphetamine and marijuana.
The Effect of Dental Health Programs in Pre-pregnancy into Low Birth Weight at Brati Public Health Center
Authors: Ardlina Nira , Firdausia Rahmadika Kemala
Published: October 2023

Background: The pregnancy period is prone to various dental health conditions that can affect pregnant women’s health and cause growth and development problems for the fetus. Neglecting dental health during pregnancy causes complications at birth, including low birth weight. This study aims to determine the effect of dental health programs for pre-pregnancy women into low birth weight at Brati Public Health Center.

Method: This research used secondary data from 80 women who participated in dental health programs for pre-pregnancy women and Antenatal Care (ANC) participants at Brati Health Center who were monitored until birth between January 2020 – June 2023. The data obtained was assessed in a questionnaire regarding the completeness of the dental health programs for pre-pregnancy women, consisting of education, examination, and dental care carried out before and after pregnancy. The data analysis used was the Mann Whitney test.

Result: Pre-pregnancy women who completed the dental health programs had a higher average birth weight (3.095 kg) than those who did not complete the program (2.076 kg). Mann Whitney test result revealed an effect between the completeness of dental health programs on pre-pregnancy to birth weight (p=0.000).

Conclusion The dental health programs for pre-pregnancy women affect the birth weight. Dental health programs for pre-pregnancy women should be carried out before pregnancy occurs, starting from the examination and education of the prospective bride. Collaboration between antenatal and dental health service providers is needed to increase access to dental prevention and treatment services needed by pre-pregnancy dan pregnant women.
Management Of Oral Candidiasis Children And Infant With Hiv/Aids Infection : Report Of Two Cases
Authors: Sari Rina Kartika , Auradewa Alrevo Panji , Sayuti Salma Qatrunnada
Published: October 2023

Background: HIV infection is characterized by progressive immunosuppression due to low absolute CD4 counts. The most common HIV-related oral disorder is oral candidiasis.

Case(s): First case, A 10-month-old baby girl complained of white plaque on her hard palate since 3 months ago.She had experienced the same before and was treated with Nystatin then the lesion resolved. She was HIV positive and took Abacavir twice a day. The latest CD4 test was 3 months ago and the result was 1000 cells/µL. The second case is an 8-year-old male patient who complained white lesion all over his mouth one week ago and treated by Nystatin for 7 days but the lesion has not resolved. He had confirmed HIV at 2.5 y.o and takes ARV regularly. The CD4 count three weeks ago was 8 cells/mm3. Both of them were diagnosed with acute pseudomembranous candidiasis

Management: The first patient was given Nystatin oral suspension 4 times a day and the lesion resolved in 1 week. The caregiver instructed to clean the child's mouth with gauze regularly. The second patient was given fluconazole 150 mg tablets 3-6 mg/kg once a day for 14 days. Both of the lesions responded well to antifungal.

Conclusion: Oral candidiasis in children with HIV often occurs in conditions of low CD4 and often appears as acute pseudomembranous candidiasis. Treatment of is adjusted to the PNPK HIV Kemenkes RI 2019 according to the level of disease
TEKNOLOJİK GELİŞMELER BAĞLAMINDA BELGESEL FİLM YAKLAŞIMLARI
Authors: AKÇORA AS Elçin , PARSA Alev
Published: October 2023

Toplumsal belleğin oluşumuna söylemleriyle katkı sunan ve kültürün taşıyıcısı konumunda olan belgesel film gelişim çizgisi içerisinde devinimsel niteliğiyle dikkat çekmektedir. Gerçeği etik paradigmalar çerçevesinde estetik duyumlarla yorumlayan belgesel filmin serüveninde bu devinimselliği tetikleyen en önemli motivasyon ise, sinema sanatının bir ifade aracı olarak teknolojinin imkanlarını yakından takip etmesidir. Dolayısıyla sosyo-ekonomik ve politik konjonktür kadar teknolojik ilerlemeler de belgesel film tarihinde kilit rol oynamaktadır. Belgesel filmin yapım aşamasındaki en önemli aygıtlarından kabul edilen kamera ve ses teknolojisinin zaman içerisinde dijitalleşmesi, yapım sonrası aşamasının en etkin araçlarından olan kurgu tekniğinin bilgisayar teknolojisiyle bambaşka bir boyuta bürünmesi belgesel film yapımını derinden etkileyen öncül teknolojik girişimler arasındadır. Teknoloji yalnızca belgeselin üretim mantığını etkilememiş aynı zamanda belgesel filmin doğuşundan bu yana elzem olan izleyiciye ulaşma şekillerini de -televizyon, bilgisayar, internet ve son olarak dijital film/dizi platformlarıyla- dönüşüme uğratmıştır. Bu bağlamda, çalışmanın temel amacı belgesel film tarihindeki bu kırılmaları açığa çıkartarak teknolojik gelişmeler çerçevesinde değişen ve dönüşen belgesel film yaklaşımlarını incelemek ve tüm bu teknik ilerlemelerin belgesel filmin anlatım dili ve estetiği üzerinde nasıl bir dönüşüme yol açtığını değerlendirmektir. Belgesel filmde bu teknik girişimlerin ardından ortaya çıkan yeni belgesel dilinin artalanıyla ilgili ulusal literatürde kısıtlı çalışmanın olması bu çalışmanın yapılmasını zaruri kılmıştır. Belgesel film alanındaki söz konusu bu yaklaşımların özetlenmesinin yanı sıra sistematik bir şekilde derlenmesi ve bir senteze ulaşılması çalışmanın literatüre sunacağı katkıların başında gelmektedir.
To the 100th Anniversary of the Birth of Professor Anatolii Ivanovych Trishchynskyi
Authors: Halushko Oleksandr , Protsiuk Olha , Loskutov Oleh
Published: October 2023

Настав 2023 рік – непростий для України і для усіх нас. Складаючи плани на майбутнє, ми згадуємо нашого Учителя, справжнього сина України Анатолія Івановича Тріщинського, 100-річчя від дня народження якого ми відзначаємо у 2023 році.
Chronic Disorders of Cerebral Circulation: a Challenge for the Family Doctor
Authors: Burchynskyi Serhii
Published: October 2023

The article examines modern views on the pathogenesis and clinical manifestations of chronic cerebral ischemia (CCI) and the possibilities of their pharmacotherapy. From this point of view, the requirements for choosing the optimal pharmacological strategy for pathological changes in the brain during ischemia are analyzed. The main goals of the clinical application of the strategy of neuroprotection in general, and in particular the need for a simultaneous effect on the neuronal, neurotransmitter and vascular mechanisms of the development of cognitive and general brain symptoms are considered.
The necessity of using membrane-protective, cholinergic and vasotropic type of action is well founded. In this regard, the risks of polypharmacy in such patients and the arguments in favor of prescribing combined drugs were analyzed.
The advantages of the innovative domestic combination containing citicoline and ginkgo biloba extract are considered in detail.
The mechanisms of action and clinical effects of these components are analyzed with an emphasis on the prospects of their use in general medical practice. Special attention is paid to the justification of new opportunities provided by the synergistic effect of citicoline and ginkgo biloba extract when they are used in the form of a combined dosage form in comparison with monotherapy with these agents. The data on the safety of the use of the specified combination, as well as the scheme of dosage and course regimens, are given. The combination of citicoline + ginkgo biloba extract opens up new opportunities for family doctors in the pharmacotherapy of early cerebral vascular insufficiency symptoms.
The Therapeutic Aspects of Obesity
Authors: Bentsa Tetiana
Published: October 2023

The prevalence of obesity has increased worldwide, reaching pandemic levels. More than half of the world’s population will be overweight or obese by 2035 without significant action, according to a report of the World Obesity Federation’s.
The World Health Organization defines overweight as body mass index (BMI) >25 kg/m2 and obesity >30 kg/m2 and describes these conditions as abnormal or excessive fat accumulation that is associated with increased health risk.
Epidemiologic studies have revealed an association between high BMI and an extensive range of chronic diseases such as non alcoholic fatty liver disease, cardiovascular diseases, diabetes mellitus, several malignancies, musculoskeletal diseases, chronic kidney disease, and mental disorders, which consequently, affect negatively subjects’ quality of life and raise healthcare costs.
Obesity as a chronic and progressive lifelong disease requires an active approach to treatment. For obese persons, it is recommended that a diet with an energy deficit of 500 kcal/day and a low energy density should be instituted for the purpose of weight loss and stabilization of a lower weight. More physical exercise in everyday life promotes weight loss and improves risk factors and obesity-associated diseases. Behavior modification and behavioral therapy support changes in nutrition and exercise in everyday life.
Pharmacotherapy for obesity can be considered if patients have a BMI of 30 kg/m2 or greater or BMI of 27 kg/m2 or greater with weight-related comorbidities. The choice of the anti-obesity medication needs to take into consideration the patient’s clinical and biochemical profile, co-morbidities, and drug contra-indications, as well as expected degree of weight loss and improvements in cardio-renal and metabolic risk.
Successful therapy for obesity depends on tailoring treatment to patients’ behaviors and comorbidities and monitoring of efficacy, safety, and tolerability.
Pharmacotherapy of Hypoactive Sexual Desire
Authors: Kocharyan Garnik
Published: October 2023

The article reports that hypoactive sexual desire occurs quite often in both sexes, but in women, such a complaint came to the first position. The article is devoted to the presentation and discussion of various medications and dietary supplements used to enhance sexual desire in women and men. Adaptogens is reported to enhance libido. Flibanserin was the first drug approved in the United States by the Food and Drug Administration (FDA) for the treatment of acquired generalized hypoactive sexual desire disorder (HSDD) in premenopausal women. Testosterone is used in men and women with a weakened libido, and Tibolone enhances sexual desire in women.
Also reported on the use of bremelanotide, the second drug approved by the FDA for the treatment of acquired generalized HSDD in premenopausal women, which is also used to increase sexual desire in men. It is informed that it also increases libido in men. In addition, bupropion and its combination with trazadone have been reported to enhance libido in women. Buspirone is reportedly used to treat sexual side effects, including diminished libido, caused by antidepressants from the selective serotonin reuptake inhibitor group.
It has been noted that the enhancing sex drive in men and women may cause Tribulus Terrestris L. use and drugs created on its basis (Tribestan and its analogues). To enhance the sexual desire, two combined drugs are tested: testosterone + sildenafil and testosterone + buspirone. Also named a number of biologically active supplements used to strengthen the weakened libido and eliminate other sexual dysfunctions.
The Role of the Cerebellum in Drug Reward: A Review
Authors: Wang Yong-bo , Lan Yan
Published: October 2023

Drug abuse remains a global problem; nonetheless, its mechanism has not yet been fully understood. Recent studies have reported on the non-motor functions of the cerebellum, and evidence from neuroimaging and behavioral studies has suggested the role of cerebellum in drug reward, which has received increasing attention. Furthermore, emerging technological developments have aided in clarifying the various circuits and functions of the cerebellum. Exploring the role of the cerebellum in drug reward can improve our understanding of the mechanism underlying addiction and facilitate the development of new treatment schemes. This review summarizes the anatomy of the cerebellum and its connections to brain regions considered important in addiction. Subsequently, we investigate the neurological reasons elucidating why the cerebellum is a potential target for drug reward. Additionally, we expound the molecular targets of addictive drugs in the cerebellum, mainly glutamate and endocannabinoids. Unlike previous studies, this article focuses on the influence of alcohol, nicotine, morphine, cannabis, and cocaine on the cerebellum from multiple viewpoints, including imaging and behavioral changes, molecular signals, neurotransmitters, and synaptic transmission. We aim to clarify some drug-induced cerebellar changes to supplement the previous research regarding the relationship between addiction and the cerebellum. Finally, we discuss the limitations and prospects of drug reward research on the cerebellum to provide novel insights into studying the cerebellum and its role in addiction. We recommend that future addiction network models should include the cerebellum to provide new therapeutic targets for treating addiction.
Neuroinflammation in the Brain and Role of Intestinal Microbiota: An Overview of the Players
Authors: Cavaliere Gina , Traina Giovanna
Published: October 2023

Great interest is aimed at understanding the inflammatory responses at the level of the central nervous system (CNS), referred to as neuroinflammatory. The environment and the duration of the inflammatory responses are essential factors for comprehending the biochemical and pathophysiological consequences induced by the inflammatory state. Specific inducers of inflammation associated with neurodegenerative disorders can activate inflammatory processes and produce mediators that potentiate neurodegeneration. Immune responders in the brain include microglial cells, astrocytes, and mast cells. A number of human pathologies are recognized to have an inflammatory component, including disorders related to brain function. Emerging evidence also attributes an important role to intestinal microorganisms in disorders related to brain function. In the gut-brain axis, the intestinal microbiota produce a variety of molecules and neurotransmitters, transform primary bile acids into secondary bile, and synthesize short-chain fatty acids. Communication within the gut-brain axis occurs through several pathways, including the immune system, the enteric nervous system, the vagus nerve, and the production of microbial metabolites. The CNS responds to this input from the gut by modulating the activity of the autonomic nervous system and the hypothalamic-pituitary-adrenal axis, which manages adrenocortical hormones. In this perspective, gut microbiota may influence neural function by influencing microglia, astroglia, and mast cells. Conversely, the relationship between neurons, microglia and synaptic alteration may also involve gut microbiota. The purpose of this review is to provide a concise overview of the mechanisms involved in communication between intestinal microbiota and the brain and how this contributes to the management of neuroinflammation.
Genetic Alterations of C-MYC Proto-Oncogene and Their Involvement in the Occurrence and Progression of Oral Cavity Cancers in Senegal
Authors: Ba Diao , Mbaye Fatimata , Diatta Henri , Samb Mame Diarra , Ndiaye Mouhamadou Makhtar , Toure Silly , Sembene Mbacke
Published: October 2023

Background: Oral cancer is the 17th most common cancer worldwide, with a mortality rate of 1.8%. Their incidence varies considerably, with a clear prevalence in South Asian countries. In Africa, the mortality rate for cancers of the oral cavity is 1.3%. Senegal is a perfect illustration a perfect illustration of the seriousness and scale of this disease, with 177 new cases recorded in 2020, for a mortality rate of 1.4%. To add to the knowledge of the molecular mechanisms involved in the carcinogenesis of these pathologies in Senegal, mutations in the C-MYC proto-oncogene were examined in 22 patients with oral cavity cancers and compared with samples from 32 control individuals. Methods: Cancerous tissue (CT) and adjacent normal tissue (ANT) were sampled from diseased individuals, whereas whole blood was obtained from control individuals (C). A total of 67 samples were collected: 32 from controls, 22 from CTs, and 13 from ANTs of diseased individuals. Total DNA was extracted and polymerase chain reaction (PCR) amplification of exon 2 of the C-MYC gene was performed, followed by Sanger sequencing. Mutation analysis was performed using Mutation Surveyor Software v5.0.1. The effect of each non-synonymous mutation on the function of the encoded protein was determined using the POLYPHEN-2, PANTHER-PSEP, and PROVEAN algorithms. The probability of non-synonymous mutations causing diseases was predicted using Prediction of human Deleterious Single Nucleotide Polymorphism (PhD-SNP) and Predicting disease associated variations using GO terms (SNP&GO). The impact of non-synonymous variations on the stability of the encoded protein was determined using I-Mutant2 and In-silico analysis of Protein Stability (INPS). Results: Of the study participants, 63% were females. The mean age of patients was 46.43 ± 13 years, with extremes of 14 and 83 years and the age range of 40–70 years as the most representative age group. Only 5% of patients were alcohol drinkers and 15% were smokers. Most patients (80%) had stage III or IV tumors with lymph node invasion. A low polymorphism rate in exon 2 of the C-MYC proto-oncogene was identified, with one synonymous substitution (Q48Q) found in a diseased individual (CT and ANT). The non-synonymous substitutions (D31N, D31E, V33G, Y36N, and Y36D) found in the controls were predicted to be damaging and pathogenic, and might decrease the stability of the encoded protein. Conclusions: Our results indicate that the C-MYC protooncogene is not involved in the occurrence and progression of oral cavity cancers in Senegalese patients. However, the mutations found in controls could provide new markers for the early clinical diagnosis of oral cancer.
ELL3 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: October 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that elongation factor for RNA polymerase II 3, encoded by ELL3, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. ELL3 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of ELL3 in primary tumors was correlated with patient distant metastasis-free survival. Modulation of ELL3 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
ZNF670-ZNF695 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: October 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that ZNF670-ZNF695 readthrough (NMD candidate), encoded by ZNF670-ZNF695, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. ZNF670-ZNF695 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Modulation of ZNF670-ZNF695 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
PACSIN3 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: October 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that protein kinase C and casein kinase substrate in neurons 3, encoded by PACSIN3, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. PACSIN3 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of PACSIN3 in primary tumors was correlated with patient overall survival. Modulation of PACSIN3 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
OSBPL2 is differentially expressed in central nervous system metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: October 2023

Metastasis to the brain occurs in a significant fraction of patients with breast cancer (1-3). We mined published RNA-sequencing and microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that oxysterol binding protein-like 2, encoded by OSBPL2, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. OSBPL2 mRNA was present at increased quantities in brain metastatic tissues as compared to primary tumors of the breast. Expression of OSBPL2 in primary tumors was correlated with patient recurrence-free survival. Modulation of OSBPL2 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Mit Händen und Füßen: Wie Luis Buñuel Belle de Jour porträtiert
Authors: Mohr Elisabeth
Published: October 2023

This is an unpublished seminar paper that has not been peer-reviewed. Its purpose is to be used as research material and not as a quotable source.
Machine Learning in Healthcare Education: Preparing the Future Workforce
Authors: Egon Kaledio , KARL LETHO
Published: October 2023

The integration of machine learning (ML) in healthcare is rapidly advancing, and there is a growing need to prepare the healthcare workforce for this transformation. This abstract highlights the significance of machine learning in healthcare education, focusing on the future health workforce's readiness to utilize artificial intelligence (AI) technologies. AI and ML applications in healthcare are making a considerable impact, and healthcare education experts recognize the importance of incorporating AI into curricula and training programs to ensure that future healthcare professionals are well-prepared to work with these technologies.
Connecting the Future: A Comprehensive Exploration of Wireless Communication Technologies
Authors: Liu Chris
Published: October 2023

Connecting the Future: A Comprehensive Exploration of Wireless Communication Technologies
Learning by Teaching in the Wild: Domain, Grades, and School Track Matter
Authors: Sibley Leonie , Russ Heike , Lachner Andreas
Published: October 2023

The use of evidence-based practice can be regarded as the gold standard in education. A steadily adopted educational practice is non-interactive teaching, in which students explain the previously learned contents to a fictitious peer. Although recent laboratory studies documented the benefits of non-interactive teaching, field-oriented evidence is scarce regarding different implementations, contents, student populations, and domains. In this field study, we applied the ManyClasses approach to test the generalizability of non-interactive teaching in diverse contexts to explore external boundary conditions (domain, school type, grading, medium and timing of the learning task) and student-related boundary conditions (age, gender, native language). We examined the effect of non-interactive teaching in k = 20 different teaching units (each 2 lessons) across various school types and subjects in which school students (N = 191) were randomly assigned to sequences of non-interactive teaching and retrieval practice (within-participants design). We did not obtain a main effect of non-interactive teaching; but the domain, school type, and grading moderated the effectiveness of teaching. The findings demonstrated the feasibility of the ManyClasses approach and highlighted the need of considering contextual variables to make generalizable recommendations for educational practice at the same time.
Best Laid Plans: A Guide to Reporting Preregistration Deviations
Authors: Willroth Emily C , Atherton Olivia E.
Published: October 2023

Psychological scientists are increasingly using preregistration as a tool to increase the credibility of research findings. Many of the benefits of preregistration rest on the assumption that preregistered plans are followed perfectly. However, research suggests that this is the exception rather than the norm, and there are many reasons why researchers may deviate from their preregistered plans. Preregistration can still be a valuable tool, even in the presence of deviations, as long as those deviations are well-documented and transparently reported. Unfortunately, most preregistration deviations in psychology go unreported or are reported in unsystematic ways. The current paper offers a solution to this problem by providing a framework for transparent and standardized reporting of preregistration deviations, which was developed by drawing upon our own experiences with preregistration, existing unpublished templates, feedback from colleagues and reviewers, and the results of a survey of 34 psychology journal editors. This framework provides a clear template for what to do when things do not go as planned. We conclude by encouraging researchers to adopt this framework in their own preregistered research, and for journals to implement structural policies around the transparent reporting of preregistration deviations.