bluuebunny/crossref_metadata_2025 huggingface dataset:
Prospective Study Regarding the Need for Repeat Potassium Testing in ED Patients with Hemolysis-Associated Pseudo-Hyperkalemia
Authors: Salo David , Hinfey Patrick , Pandey Devansh , Bernard Renae , Gill Randy , Fiesseler Frederick
Published: February 2022

Objectives: Many ED patients who have hyperkalemia (HK) with evidence of hemolysis have pseudohyperkalemia (PHK) and may not require repeat potassium (K) testing, though ED physicians often redraw levels. We sought to determine if a set of patients with PHK could be determined who would not require repeat K draws based on lab and medication/co-morbid conditions.
Methods: This was a prospective IRB-approved study at an 85,000 patient/yr inner-city ED. Data was analyzed to determine whether repeat K draws were necessary in patients with HK plus hemolysis who had normal renal function (NFR) defined by either Cr or GFR and to determine factors that might lower retest threshold and prevent unnecessary repeat K testing. Normal renal function was defined as Cr < 1.3 or GFR > 60 (calculated by the Modification of Diet in Renal Disease (MDRD) equation:. HK was defined as K > 5.3 mEq/L. ED patients with K draws showing HK plus hemolysis with repeat metabolic panel performed within 12 hours were eligible.
Results: 300 patients had HK with hemolysis with repeat testing during the study period. Four were excluded due to missing/incomplete data. Two patients had renal failure and were excluded. 238 had repeat K sent prior to, or without specific HK treatment and were further analyzed. The median age was 60, range 76, IQR 46-75. 153/238 (64.2%) were female, 200/238 African-American (84%), 169/238 (71%) had normal GFR while 182/238 (76.8%) had normal Cr. Twenty-four of the 238 (10%) had persistent HK on the 2nd lab draw. Factors on univariate analysis associated with HK on repeat testing were age, gender, diuretic use, PVD, DM, and abnormal BUN, Cr or GFR. Binary logistic regression showed abnormal Cr, age and PVD as significant predictors of persistent HK. ROC curves of Cr and age were generated and further analysis showed Cr >1.4, age > 63, or PVD would have identified 22/24 cases of persistent hyperkalemia (the two patients showing persistent hyperkalemia had potassium levels that did not require treatment). This resulted in a decreased need for retesting in 53.7% of patients.
Conclusion: By using 3 variables: Cr >1.4, age > 63, and history of PVD, 115/214 (53.7%) of patients with initial HK with hemolysis would not require repeat blood draw for potassium testing, while 2/24 patients with persistent HK would have been missed. These 2 patients had marginally elevated potassium that would not have required treatment. Since some variables reported to be associated with hyperkalemia were not present or were present in low numbers, physicians may need to repeat testing on select or sicker patients who they suspect may have true HK, however up to 50% of patients will not require such testing.
Prevalence and Associated Risk Factors of Iron Deficiency Anemia Among School Teenagers in Mbouda, Western Cameroon: A Cross Sectional Study
Authors: Tadzong Mamokem O. , Kana Sop M. M. , Takougoum Marbou W. J. , Telefo B. P.
Published: February 2022

Teenagers are a particularly vulnerable age group to Iron Deficiency Anemia (IDA). This study aimed to determine the prevalence and associated risks factors of IDA among apparently healthy school teenagers in Mbouda, West-Cameroon. Blood samples, up to 778 were randomly collected from adolescents aged 10-19 years of four schools in Mbouda. For this cross-sectional study, participants collaborated to fill a questionnaire with us on socio-economic and demographic status. The methods of 24 hours recall, and dietary history were used to determine the dietary habits, the type of food and the consumed meal frequencies during a day. Appropriate indicators including hemoglobin and hematocrit, serum iron, ferritin, transferrin, and total iron binding capacity, transferrin saturation were determined using standard methods. Our findings showed that the prevalence of IDA was 82.4 % and 17.64 % in participants aged 13-19 years and 10-12 years respectively. High significant difference in the mean values of Serum Iron (p = 0.001), Serum ferritin (p<0.001), TIBC (p<0.001), CST (0.001) and Hemoglobin (p<0.001, CI = 2) were observed in participants without IDA compared to those with IDA. The sociodemographic risk factors of IDA in school adolescents were sex [P = 0.001, OR = 0.39 (0.22–0.69)], residence areas [P = 0.001, OR = 3.30 (1.55–7.02)] and school sites [P = 0.002]. Consumption of vegetable [OR: 0.30 (0.17–0.54)], fruits, [OR: 0.26 (0.12–0.52)] and fats [OR: 0.33 (0.12–0.91)] significantly decreased the risk of IDA (p <0.05), whereas the consumption of legumes [OR: 2.60 (1.57–4.32)] significantly increased the risk of IDA. This study suggested that IDA could be prevented by providing proper knowledge on the healthful diet including fats animal food sources, fruit and vegetables, improved lifestyle, and on the harmful effects of IDA to the teenager’s productivity.
PENERAPAN METODE KLASIFIKASI DECISION TREE UNTUK MEMPREDIKSI KELULUSAN TEPAT WAKTU
Authors: Dina Rachmawaty Jauhar Ma’sum Atik Febriani
Published: February 2022

Pendidikan adalah usaha sadar dan terencana untuk mewujudkan suasana belajar dan proses pembelajaran agar peserta didik secara aktif mengembangkan potensi dirinya. Minimnya pemanfaatan data yang tersimpan membuat data ini kurang memberikan nilai tambah terhadap institusi. Oleh sebab itu, diperlukan adanya pemanfaatan data-data tersebut agar menghasilkan sebuah pengetahuan yang bermanfaat bagi program studi dan perguruan tinggi. IT Telkom memiliki 3 fakultas, terdiri dari 12 program studi S1 dan 1 program studi D3. Pada tahun 2017, jalur masuk yang dibuka oleh IT Telkom Purwokerto adalah Mandiri, Kemitraan, dan Prestasi Tujuan dari penelitian ini adalah untuk memprediksi perfomansi mahasiswa dalam menyelesaikan masa studi tepat waktu. Batasan penelitian ini yaitu hanya pada program sarjana Institut Teknologi Telkom Purwokerto. Atribut yang digunakan pada penelitian ini adalah cluster asal daerah berdasarkan PDRB, program studi, jalur masuk, asal sekolah, bidang keahlian, IPK semester ganjil 2019/2020, dan status kelulusan TA 1 dan Seminar Proposal. Sumber data pada penelitian ini diperoleh dari bagian Penerimaan Mahasiswa Baru (PMB), Akademik Institusi, dan SISFO. Metode yang digunakan pada penelitian ini adalah metode klasifikasi decision tree. Penelitian ini menghasilkan 63 rules dengan akurasi 68,49% dengan nilai precision 79,63% dan nilai recall 55,13%.
ANALISIS POSTUR KERJA KARYAWAN PEMINDAHAN BEAM BENANG DENGAN METODE REBA PADA DIVISI PERSIAPAN PT SUKUNTEX
Authors: Akh. Sokhibi Fathan Ainun Najib
Published: February 2022

Postur kerja yang tidak tepat dapat mengakibatkan turun- nya performa kerja dan berpengaruh pada produktivitas kerja. perbaikan postur kerja dapat diupayakan dengan penerapan metode kerja yang ergonomi. PT Sukuntex merupakan perusahaan manufaktur yang mengolah benang menjadi kain (textile). Pengamatan di PT Sukuntex ditemukan aktivitas 2 karyawan melakukan pemindahan beam benang dari divisi persiapan ke divisi tenun dengan menggunakan alat bantu yang masih sederhana serta belum ergonomi. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana postur kerja karyawan pemindahan beam benang PT Sukuntex serta untuk memberikan solusi dalam mengurangi resiko cidera karyawan. Analisis postur kerja dilakukan dengan membagikan Kuesioner Nordic Body Map (NBM) untuk mengetahui keluhan sakit pada tubuh karyawan saat bekerja dan metode Rapid Entire Body Assesment (REBA) dengan software Ergofellow untuk mengidentifikasi resiko cidera serta tingkat tindakan yang perlu dilakukan. Berdasarkan hasil kuesioner NBM didapatkan hasil dengan presentase tertinggi 8% karyawan merasakan sakit pada lutut kanan. Hasil analisis REBA mendapatkan skor 8 untuk aktivitas karyawan 1 mengangkat beam. Skor 11 untuk aktivitas karyawan 2 mengangkat beam. Skor 10 untuk aktivitas karyawan 1 dan 2 saat mendorong dan menarik beam.
EVALUASI PEMESANAN BAHAN BAKU TEBU DI PG TRANGKIL MENGGUNAKAN METODE ECONOMIC ORDER QUANTITIY
Authors: Dina Tauhida Lailatul Musfiroh
Published: February 2022

PT Kebon Agung PG Trangkil merupakan industri manufaktur yang bergerak pada bidang agribisnis yang menghasilkan gula sebagai produk utama. Gula merupakan sembako yang sangat dibutuhkan oleh masyarakat. Kehabisan bahan baku bisa mengakibatkan proses giling berhenti dan tidak mencapai target. Hal tersebut bisa menyebabkan biaya produksi menjadi boros karena target tidak terpenuhi akan tetapi proses produksi semakin berlanjut. PG Trangkil mengambil bahan baku dari kebun perusahaan dan kebun petani. Persediaan bahan baku dilakukan setiap hari pada musim giling berlangsung yaitu sekitar 4-6 bulan. Dalam kasus ini peneliti mengusulkan untuk menggunakan metode EOQ untuk memastikan persediaan bahan baku seefisien mungkin serta sesuai kebijakan perusahaan.
Cacao-based Agroforestry in Conservation Forest Area: Farmer Participation, Main Commodities and Its Contribution to the Local Production and Economy
Authors: Murniati Murniati , Suharti Sri , Yeny Irma , Minarningsih Minarningsih
Published: February 2022

Cacao-based agroforestry systems have been developed in the conservation forest area of Wan Abdul Rachman Grand Forest Park (WAR GFP). Previously, the forest areas were occupied by surrounding needy communities, causing land-use conflict and forest degradation. To resolve these problems, the conservation forest manager developed a conservation partnership program, giving farmers legal access to establish cacao agroforestry systems while improving forest conditions. This research aimed to study the farmers’ participation, main commodities of the cacao-based agroforestry system, and its contribution to the local production and economy. This research was conducted in 2018 and 2019. The field survey was used to characterize the agroforestry system practiced and a series of interviews with two respondent groups, stakeholders concerned with WAR GFP management (nine key informants), and cacao-based agroforestry farmers (61 respondents). The agroforestry systems were dominated by cacao trees mixed with other tree crops and forest trees with an average density of 1,169.3 ± 668.3 trees/ha. Community involvement in the agroforestry development has only reached "Placation" or level 5 of Arnstein's participation ranking, implying they are granted limited opportunities to participate in the agroforestry development. Cacao production was influenced by the cacao tree and the associated tree density. Optimal cacao production as much as 367.4 ± 357.9 kg/ha was achieved at 1,253 trees/ha of total tree density. Besides cocoa, there were 13 primary commodities, where some have contributed more than 40% to district production. Income gained from the agroforestry systems contributes significantly (75.63%) to total farmers’ income. It can fulfill households’ basic needs and has exceeded the poverty line at the national level. The cacao-based agroforestry development has become an alternative to resolve land use conflict in conservation forest areas characterized by land scarcity with a dense population
Application of Sobolev-Volterra projection and finite element numerical analysis of integral differential equations in modern art design
Authors: Tan Zheng , Albarakati Abdullah
Published: February 2022

The article uses the Spss statistical analysis software to establish a multiple linear regression model of short-term stock price changes in domestic agricultural listed companies. It uses a stable time series based on the ARMA model for stable agricultural value-added, fiscal expenditure and market interest rates. The regression method is used to study its impact on the stock price index. Compared with the existing stock forecasting methods, this method has simple data collection and no specific requirements for data selection, and the prediction results have a high degree of fit. Therefore, this method is suitable for most stocks.
Optimal preview repetitive control for impulse-free continuous-time descriptor systems
Authors: Lan Yong Hong , Zhao Jia Yu , Wang Zhao Hong
Published: February 2022

This paper concerns the design problem of optimal preview repetitive control (OPRC) for impulse-free continuous-time descriptor systems. First, by using a linear transformation, the descriptor system is transformed into a normal system with relatively low dimensionality and an algebraic system. Based on this, an augmented system which contains the error vector and the derivative of the normal system is constructed. Then, applying the lift technique and introducing a new performance index, the OPRC designing problem is converted into a regulation problem. Based on the optimal control theory, the regulator problem of the augmented system is solved. Furthermore, the explicit OPRC law for the original system is deduced. Different from the existing results, the preview feed-forward and error integral compensations are added into the OPRC system, which can significantly improve the tracking performance. Finally, a numerical example simulation result verifies the validity of the proposed method.
Coronavirus Disease 2019 (COVID-19): A literature review
Authors: Sari Gusti Ayu Putu Laksmi Puspa
Published: February 2022

Kasus pertama COVID-19 dilaporkan pada Desember 2019 ketika sekelompok pasien dirawat di rumah sakit di Wuhan, ibukota provinsi Hubei di Cina, yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Awalnya, berjangkitnya SARS CoV-2 hanya terbatas di provinsi Hubei, tetapi menyebar dengan cepat ke banyak negara lain, dan Organisasi Kesehatan Dunia secara resmi mendeklarasikan pandemi global pada 11 Maret 2020. Secara umum, coronavirus menyebabkan penyakit sistem pernapasan, pencernaan, dan sistem saraf pusat yang meluas pada manusia dan hewan lain, mengancam kesehatan manusia dan menyebabkan kerugian ekonomi. Masih banyak kontroversi seputar penyakit ini, termasuk tata laksana hingga pencegahan. Oleh karena itu, saya melakukan telaah terhadap studi-studi terkait COVID-19. Dalam ulasan literatur ini, penyebab, patogenesis dan respon imun, epidemiologi, diagnosis, perawatan dan manajemen strategi penyakit, kontrol dan pencegahan semuanya ditinjau.
Efektifitas Pemberian Edukasi untuk Meningkatkan Pengetahuan Mengenai Pengobatan Asma dan Inhaler pada Apoteker Komunitas di Surabaya
Authors: Lorensia Amelia , Yudiarso Ananta , Syarifah Diana , Susanti Ni Wayan Deviani
Published: February 2022

Pengobatan asma kurang optimal dapat disebabkan kurangnya pengetahuan dari apoteker sebagai tenaga kesehatan yang berperan memberikan informasi bagi pasien. Peran apoteker dibutuhkan karena apoteker berinteraksi langsung dengan pasien di apotek. Tujuan dari penelitian ini adalah mengetahui pengetahuan apoteker dengan pengaruh edukasi yang diberikan mengenai asma dan inhaler di wilayah Surabaya. Metode penelitian adalah pra-eksperimen dengan desian studi one group pre-post-test. Penelitian ini menggunakan kuisioner mengenai asma dan alat inhaler yang dinilai sebelum dan sesudah edukasi. Edukasi dilakukan dalam bentuk educational meeting yang aktivitasnya berupa workshop dalam berbagai format yang berfokus pada pengetahuan apoteker terhadap penyakit asma dan inhaler dengan mengunjungi apoteker satu per satu.  Pengambilan sampel dengan metode non random sampling, menggunakan teknik purposive sampling. Data yang diperoleh akan diolah dengan analisis deskriptif dan analisis inferensial dengan paired t-test. Dari hasil pengumpulan data, 68 apoteker komunitas bersedia mengisi kuisioner pre-test dan hanya 20 apoteker yang bersedia diedukasi serta mengisi kuisioner post-test. Pada penelitian ini diperoleh nilai p(0,000)?0,05 yang menunjukkan ada perbedaan signifikan antara pengetahuan sebelum dan sesudah pemberian edukasi untuk meningkatkan pengetahuan asma dan inhaler. Meskipun efektif, namun terdapat beberapa materi pengetahuan yang tidak dapat ditingkatkan terutama mengenai penatalaksanaan asma, yang sangat dipengaruhi oleh kurangnya pengalaman dalam penanganan pasien asma di apotek.
Formulasi Emulgel Minyak Ikan Salmon dengan Gelling Agent Na-Alginat dari Alga Coklat (Sargassum sp)
Authors: Najih Yuli Ainun , Rakhma Dita Nurlita , Utami Arum Sari Diyah , Andayani Rina
Published: February 2022

Penelitian ini bertujuan untuk mengetahui kemampuan Na-alginat yang berasal dari Sargassum sp sebagai gelling agent dalam sediaan emulgel minyak ikan salmon. Pembuatan formula emulgel minyak ikan salmon menggunakan gelling agent Na-alginat dari isolasi alga coklat (Sargassum sp) dengan konsentrasi 3% dan 4%. Uji karakterisasi Na-alginat dari alga coklat (Sargassum sp) meliputi uji organoleptis, RVA, FTIR dan DSC. Pembuatan emulgel dilakukan dengan melebur fase minyak dan fase air di atas hot plate menggunakan termometer untuk mengontrol suhu 70ºC. Kedua fase ini dicampur dan diaduk dengan kuat sampai terbentuk emulsi. Fase gel dibuat dengan mendispersikan Na-alginat dari alga coklat (Sargassum sp) dalam mortir. Karakteristik minyak ikan salmon meliputi organoleptik, pH, viskositas, dan daya sebar. Stabilitas dilakukan dengan uji sentrifugasi. Hasil penelitian menunjukkan bahwa semua formula emulgel memiliki penampilan fisik yang sama dari minyak ikan emulgel dengan tekstur yang agak kasar dan tidak lengket, berwarna coklat muda dan memiliki bau khas minyak ikan. Semua formula memiliki rentang pH kulit. Pengukuran viskositas menunjukkan perbedaan yang signifikan (p <0,05) untuk setiap formula, yang F2 (87.000 cPs ± 12.124) memiliki viskositas yang lebih tinggi daripada F1 (33.333 cPs ± 14.011). Uji daya sebar menunjukkan tidak ada perbedaan signifikan untuk setiap formula. Uji sentrifugasi tidak menunjukkan pemisahan fase setelah pengujian. Berdasarkan semua hasil tersebut, dapat disimpulkan bahwa konsentrasi Na-Alginat mempengaruhi karakteristik fisik emulgel minyak ikan salmon untuk viskositas, dan tidak mempengaruhi stabilitas fisik. Semua formula membentuk sistem yang stabil.
Hubungan Kepatuhan Hemodialisis dengan Disfungsi Seksual Wanita Usia Subur di RSUD Ungaran
Authors: Kuway Yacomina , Sujana Tressia , Tampubolon Rifatolista
Published: February 2022

Abstract

 

Female patients with chronic kidney failure undergoing hemodialysis therapy have various health problems, one of which is sexual dysfunction. Sexual dysfunction was experienced in the form of sexual desire disorders, arousal, lubrication, orgasm, satisfaction, and pain. This study aims to determine the relationship of hemodialysis compliance with sexual dysfunction of women of childbearing age at Ungaran District Hospital. The research design used is the quantitative correlation with a cross-sectional approach. The research sample is women of childbearing age with an age range of 25-34 years to 35-44 years. The results of the study with Chi-Square analysis showed a significance value (Sig) 0.542 (p = 1,000) or > 0.05 which means there was no significant relationship between hemodialysis adherence with sexual dysfunction of women of childbearing age at Ungaran District Hospital. the conclusion of this study is that factors such as lack of sexual desire are the main reason there is no relationship between the two variables.

 

Keywords: Female patients with chronic renal failure, hemodialysis compliance, sexual dysfunction.

 

Abstract

 

Pasien wanita gagal ginjal kronik yang menjalani terapi hemodialisis mempunyai berbagai masalah kesehatan, salah satunya ialah difungsi seksual. Disfungsi seksual yang dialami berupa gangguan keinginan seksual, gairah, pelumasan, orgasme, kepuasan dan nyeri. Penelitian ini bertujuan untuk mengetahui hubungan kepatuhan hemodialisis dengan disfungsi seksual wanita usia subur di RSUD Ungaran. desain penelitian yang digunakan adalah kuantitatif korelasi dengan pendekatan cross-sectional. Sampel penelitian ialah wanita usia subur dengan rentang usia 25-34 tahun hingga 35-44 tahun. Hasil penelitian dengan analisis Chi-Square menunjukan nilai signifikansi (Sig) 0,542 (p=1.000) atau > 0,05 yang berarti tidak terdapat hubungan yang bermakna antara kepatuhan hemodialisis dengan disfungsi seksual wanita usia subur di RSUD Ungaran. kesimpulan dari penelitian ini adalah faktor seperti kurangnya keinginan seksual menjadi alasan utama tidak terdapat hubungan antara kedua variabel.

Kata Kunci: Pasien wanita gagal ginjal kronik, kepatuhan hemodialisis, disfungsi seksual.
Pengaruh Faktor Sosial Demografi dan Sosial Ekonomi terhadap Tindakan Pemilihan Obat Tradisional dalam Upaya Pengobatan Mandiri di Kalangan Masyarakat Kecamatan Landasan Ulin Kota Banjarbaru
Authors: Fitriah Rahmayanti , Noormalisa Noormalisa
Published: February 2022

Penggunaan obat tradisional semakin berkembang baik sebagai obat maupun untuk tujuan yang lain, terlebih dengan adanya anjuran untuk kembali kealam. Permasalahan akan timbul apabila tindakan pemilihan obat tradisional tersebut adalah sebagai bentuk pelarian dari pelayanan medis. Tujuan dari penelitian untuk mengetahui pengaruh faktor sosial demografi dan sosial ekonomi terhadap tindakan pemilihan obat tradisional dalam upaya pengobatan mandiri di kalangan masyarakat Kecamatan Landasan Ulin. Penelitian ini bersifat deskriptif analitik dengan pendekatan crossectional. Populasi dalam penelitian ini adalah seluruh masyarakat Kecamatan Landasan Ulin Kota Banjarbaru Tahun 2019 yang berjumlah 67,535 orang dengan sampel 100 orang. Metode pengambilan sampel purposive sampling. Pengumpulan data dilakukan dengan menggunakan kuesioner dan telah dilaksanakan pada bulan januari – maret 2019. Analisa data menggunakan uji Chi-Square dengan tingkat kemaknaan 95% (? = 0.005) dari hasil penelitian dapat diketahui bahwa tidak ada pengaruh antara sosial demografi dan sosial ekonomi terhadap tindakan pemilihan obat tradisional.
Pengaruh Media Edukasi BOGIMBA (Boneka dan Dongeng Gizi Seimbang) terhadap Tingkat Pengetahuan Anak tentang Gizi di TK Islam Silmi Samarinda
Authors: Mulya Ainur Basirah , Aminyoto Meiliati , Hasanah Nurul
Published: February 2022

The main causes of the nutritional problems is poor diet. Knowledge became one of the aspects that affect it. Therefore, it is extremely important nutrition education given at an early age. This study aims to determine the effect of educational media BOGIMBA (Doll and Tale of Balanced Nutrition) to the level of knowledge of children about nutrition to the type of analytical research quasi-experimental method is based on the design of one group pretest-posttest. This research sample using the entire sample of the population that met the inclusion criteria of research to obtain 51 respondents. The variables measured in this study are BOGIMBA educational media and level of knowledge of children about nutrition. From the research conducted, it was found the influence of educational media BOGIMBA to increase children's knowledge about nutrition (p = 0.000).
Identifikasi Faktor-Faktor Terkait Kejadian Preeklamsia Pada Ibu Hamil Di Kabupaten Semarang
Authors: Ernawan Paulina Budiarty , Tampubolon Rifatolistia , Bagus Remigius
Published: February 2022

Latar belakang: Angka Kematian Ibu (AKI)merupakan salah satu indikator dalam menentukan derajat kesehatan masyarakat suatu negara. Kesehatan ibu menjadi salah satu aspek penting dalam mendukung program pembangunan kesehatan di Indonesia. Penurunan jumlah AKI merupakan salah satu target dalam programMillenium Development Goals (MDGs) yang kini telah berganti menjadi Sustainable Development Goals (SDGs), sehingga pembahasan mengenai kejadian preeklamsia yang berdampak pada kematian ibu menjadi sangat penting. Tujuan: untuk mengidentifikasi faktor-faktor yang terkait dengan kejadian preeklamsia pada ibu hamil di Kabupaten Semarang. Metode: Penelitian ini adalah penelitian kuantitatif dengan pendekatan retrospektif. Populasi dalam penelitian ini adalah ibu hamil dengan diagnosa medis preeklamsia pada tahun 2016-2018. Teknik sampling pada penelitian ini menggunakan kuota sampling, sampel yang terkumpul sebanyak 30 responden dalam kurun waktu dari tahun 2016-2018. Pengumpulan data dengan menggunakan instrumen penelitian berupa kuisioner yang karakterisitik pertanyaan berisi perilaku ANC, pola hidup, riwayat penyakit, status paritas. Hasil penelitian ini disajikan dalam bentuk tabel, bagan, persentase dan rerata dari hasil penelitian. Dari hasil penelitian diperoleh 60% ibu dengan risiko rendah (20-35 tahun), tingkat pendidikan 86,6% (SMA/SMK), pekerjaan 70% (ibu rumah tangga), pemeriksaan ANC 100%, status gravida 73,3% (multigravida), kehamilan kembar 0%, pola hidup makan teratur 100%, konsumsi buah dan sayur 50%, olah raga rutin pada trimester III (43,3%), riwayat hipertensi 30%, obesitas 10%. Faktor yang terkait dengan kejadian preeklamsia dalam penelitian ini diantaranya adalah riwayat pendidikan, pekerjaan, status multipara ibu dan status gizi berlebih dan obesitas.
Uji Aktivitas Antibakteri Sediaan Gel Hand Sanitizer Ekstrak Kulit Buah Jengkol (Archidendron pauciflorum (Benth.) Nielsen) terhadap Bakteri Escherichia coli
Authors: Hidayati Rizka Ahyar , Kristijono Ary , Muadifah Afidatul
Published: February 2022

Escherichia coli is a bacteria that can cause diarrhea. The emergence of diarrhea is caused by a lack of public awareness in maintaining cleanliness, including hand hygiene. Along with the times, people prefer to use hand sanitizers that are more practical, easy to carry, and easy to use. However, most hand sanitizer preparations contain alcohol which has the potential to cause dryness and irritation if used continuously. Therefore, jengkol rind is used which contains flavonoid compounds, saponins, tannins, and anthraquinones which have antibacterial properties against Escherichia coli. The purpose of this study was to determine the antibacterial activity of the hand sanitizer gel of jengkol fruit peel extract against Escherichia coli using the disc diffusion method. The research method used was experimental. The jengkol rind samples were extracted using the maceration method with 70% ethanol. The positive control used was a hand sanitizer with chloroxylenol content and the negative control was a gel base without extract. Jengkol rind extract is made into preparations in concentrations of 5%, 10%, and 15%. The preparation was tested for physical stability for 28 days including organoleptic, pH, homogeneity, dispersibility, adhesion, protective power, and drying time. The results showed that the preparations with a concentration of 5%, 10%, and 15% jengkol fruit peel extract had an average inhibition zone of 7.00 ± 0.8165 mm, 13.00 ± 0.8165 mm, and 17.25 ± 0.95743 mm. Of the three formulations, the formulation with a concentration of 10% is the most effective concentration because a small concentration already has a strong inhibitory power category. The hand sanitizer gel of jengkol fruit peel extract fulfills the requirements for organoleptic tests, homogeneity, pH, spreadability, adhesion, and protection power and is stable in the 28-day storage period, but does not meet the requirements for drying time.
Uji Aktivitas Antibakteri Fraksi Daun Eceng Gondok (Eichhornia crassipes) terhadap Bakteri Staphylococcus aureus
Authors: Qur’an Shindy Charisma Nur , Huda Choirul , Martha Rahma Diyan
Published: February 2022

Staphylococcus aureus merupakan bakteri Gram positif yang memiliki habitat alami pada manusia dan mudah resisten terhadap antibiotik. Alternatif yang lebih aman untuk mengatasi masalah infeksi Staphylococcus aureus yaitu dengan memanfaatkan bahan aktif antimikroba dari tanaman obat. Salah satu tanaman yang dapat digunakan adalah eceng gondok. Eceng gondok merupakan tanaman yang memiliki kemampuan mengahambat aktivitas bakteri. Tujuan penelitian ini adalah untuk mengetahui aktivitas antibakteri maserat ekstrak, fraksi teraktif dari fraksi etanol 96%, fraksi diklorometana, fraksi N-heksan dan konsentrasi optimum fraksi aktif daun eceng gondok terhadap bakteri Staphylococcus aureus. Daun eceng gondok diekstraksi menggunakan metode maserasi dengan pelarut etanol 96% dan dilakukan proses fraksinasi menggunakan pelarut etanol, diklorometana dan N-heksan. Uji aktivitas antibakteri dilakukan metode difusi cakram kertas. Fraksi teraktif dilakukan seri konsentrasi 15%, 30%, dan 45%. Hasil uji aktivitas antibakteri menunjukkan maserat ekstrak daun eceng gondok memiliki aktivitas antibakteri dengan diameter rata-rata 10,3 mm. Fraksi etanol merupakan fraksi teraktif yang memiliki aktivitas antibakteri terhadap bakteri Staphylococcus aureus dengan hasil rata-rata diameter 21 mm. Konsentrasi optimum dari fraksi teraktif adalah konsentrasi 15% dengan diameter rata-rata 13,67 mm
Review: Analisis Komponen Senyawa Kimia Krokot (Portulaca oleraceae L. dan Portulaca grandiflora Hook.)
Authors: Husein Sri Gustini , Sundalian Melvia , Husna Nurul
Published: February 2022

Purslanes are medicinal plants from the Portulacaceae family which has more than 100 species, including Portulaca oleraceae L. and Portulaca grandiflora Hook. Both types of purslanes have the potential to become natural medicines due to the presence of active chemical compounds that produce various pharmacological effects. This review compiled the data concerning chemical compounds found in those two types of purslanes, the method of analysis, as well as the factors that affect the quality and quantity of chemical compounds so that they can be used as references in determining natural medicinal ingredients by selecting purslanes based on their desired phytochemical compounds and the appropriate analysis. The data were collected by a method of searching research journals on Google Scholar using certain keywords. From this review, the results showed that the chemical compounds found in the two types of purslanes are phenolic, flavonoid, fatty acid, sterol, terpenoid, and alkaloid. These components can be analyzed using spectroscopic and chromatographic methods for both qualitative and quantitative analysis. Some factors that need to be considered in the analysis of these components are the analytical method used, the method of extraction, the solvents, the plant varieties and genotypes, the part of the plant used, the growth time and harvest time of the sample, and the conditions in which the samples grew.
Aktivitas Analgetika dan Antiinflamasi Ekstrak Etanol dan Fraksi Daun Jambu Mawar (Syzygium jambos L.) Secara In Vivo
Authors: Winda Suwandi Deden , Puspita Tita , Nuari Doni Anshar , Hamdani Syifa
Published: February 2022

Syzygium jambos is a plant that has traditionally been used to treat several diseases, especially the leaves as a medicine for rheumatism. In this study, the ethanol extract, fraction of n-hexane, ethyl acetate, and water from its leaves were tested for analgesic and anti-inflammatory activity using the writhing method (Siegmund), hot plate, and the formation of swelling of the soles induced by carrageenan lamda. The results showed that the ethanol extract at doses of 100 and 200 mg/kg BW and fractions of n-hexane, ethyl acetate and water at doses of 50 and 100 mg/kg BW had analgesic and anti-inflammatory activities. The ethanol extract at doses of 100 and 200 mg/kg BW can reduce the amount of writhing every 5 minutes for 60 minutes of observation by 84 and 98 times with percent protection of 58.0 and 52.0%. The Ethyl acetate, n-hexane, and water fractions of 50 and 100 mg/kg BW can reduce the amount of animal writhing by 93 and 35 times, 75 and 100 times, as well as 84 and 124 times with the percent of protection is 54.45 and 82.85, 63.0 and 50.9, as well as 58.47 and 38.02%. The analgesic activity of the hot plate method, ethanol extract can increase the survival time of animals in the hot plate by 154.0 and 95.02%, while the animal survival time of the n-hexane fraction is 95.86 and 105.5, ethyl acetate by 143, 7 and 105.7, and the water fraction of 34.1 and 99.5%. The anti-inflammatory activity of ethanol extract at doses of 100 and 200 mg/kg BW was indicated by a decrease in the volume of rat leg edema at the time of observation for 6 hours with the percent inhibition of edema of 59.2 and 41.12%. The n-hexane, ethyl acetate, and water fractions have relatively the same ability, indicated by the edema inhibition value of the n-hexane fraction of 68.24 and 68.56%, the ethyl acetate fraction of 57.08 and 67.32% and the fraction water of 64.02 and 67.46%. The effective dose of extracts and fractions of n-hexane, ethyl acetate, and water as analgesics and anti-inflammatory is 100 mg/kg BW.
Penggunaan Antibiotik Restriksi pada Pasien Sepsis di Ruang ICU RSUD H. Abdul Manap Kota Jambi Periode 2017-2019
Authors: Bardani Fidya Rizky , Andriani Yuni , Rahmadevi Rahmadevi
Published: February 2022

Saat ini resistensi antibiotik menjadi perhatian dunia karena dampaknya terhadap peningkatan angka morbiditas, mortalitas, biaya terapi dan kegagalan terapi. Pada ruang yang dibatasi disebut juga dengan antibiotik restriksi. Penelitian ini bertujuan mengetahui persentase penggunaan antibiotik restriksi pasien Sepsis di Ruang ICU RSUD H. Abdul Manap Kota Jambi periode 2017-2019. Penelitian ini merupakan penelitian deskriptif dengan pengambilan ICU, penggunaan antibiotik terbilang tinggi, sehingga risiko resistensi antibiotik juga tinggi. Restriksi antibiotik merupakan strategi di dunia kesehatan untuk mengurangi kejadian resistensi antibiotik dengan cara membatasi penggunaan antibiotik, antibiotik data secara retrospektif dan menggunakan teknik purposive sampling. Terdapat 38 pasien yang memenuhi kriteria inklusi. Hasil penelitian karakteristik pasien menunjukkan sampel dominan perempuan 21 pasien (55,3%), rentang usia >65 tahun 15 pasien (39,5%), lama rawatan <7 hari 21 pasien (55,3%), meninggal 23 pasien (60,5%) dan penyakit penyerta DM Tipe II 4 pasien (12,5%). Hasil penelitian antibiotik restriksi yang digunakan pasien meliputi: meropenem 31 pasien (69%), levofloxacin 7 pasien (15,6%), ciprofloxacin 2 pasien (4,5%), cipoferazon 1 pasien (2,2%) dan ceftazidim 1 pasien (2,2%). Angka persentase penggunaan antibiotik restriksi dari tahun 2017 – 2019 adalah 100%, 75% dan 76%. Kesimpulan pada penelitian ini yaitu nilai persentase penggunaan antibiotik restriksi pada pasien Sepsis mengalami penurunan pada tahun ke-2 dan cenderung menetap di tahun berikutnya. Nilai persentase tertinggi yaitu ditahun 2017 sebesar 100% terendah ditahun 2018 sebesar 75%.
Hubungan Jenis Plasmodium falciparum dan Plasmodium vivax dengan Kejadian Anemia pada Pasien Malaria di RSUD Ratu Aji Putri Botung Penajam Paser Utara
Authors: Suryadi Doni , Toruan Vera Madonna Lumban , Sihotang Fransiska Anggreni , Siagian Loly Rotua Dharmanita
Published: February 2022

Malaria is a disease caused by Plasmodium infection that is still a health problem in the tropical area including Indonesia. Penajam Paser Utara is the only district with a high level of malaria endemicity outside eastern of Indonesia which is located at the Province of East Kalimantan. Malaria can cause various complications including haematological abnormalities. Haematological abnormalities that are often found in both falciparum malaria and vivax malaria is anaemia. The purpose of this study was to determine the relationship between the types of Plasmodium falciparum and Plasmodium vivax with the incidence of anaemia in malaria patients at Ratu Aji Putri Botung, Penajam Paser Utara hospital. This research is an observational analytic study with cross sectional method. The data was obtained from medical records of hospitalized malaria patients at Ratu Aji Putri Botung Penajam Paser Utara hospital in the period of January 2013 – August 2018 by purposive sampling method. The data were analyzed using the Chi-square test. The subjects of the study were 310 malaria patients consisting of 60,3% (n=187) patients infected with Plasmodium falciparum and 39,7% (n=123) patients infected with Plasmodium vivax. The majority of research subjects were male (95,8%) and were in the 26 – 40 years age group (56,5%). Anaemia was found in 49% of malaria patients dominated by vivax malaria patients (52%). Statistical test result between types of Plasmodium with the incidence of anaemia was p = 0,391. It was concluded that there was no association between the types of Plasmodium falciparum and Plasmodium vivax with the incidence of anaemia in malaria patients.
Uji Daya Hambat Bakteri Staphylococcus Aureus Sabun Cuci Tangan Cair Berbahan Arang Aktif Batok Kelapa
Authors: Lestari Dian Fita , Fatimatuzzahra Fatimatuzzahra , Dominica Dominica
Published: February 2022

Infeksi dapat disebabkan oleh bakteri patogen diantaranya bakteri Staphylococcus aureus. Penggunaan antibakteri dari bahan sintetik dapat mencegah terjadinya infeksi, namun tidak sedikit yang memberikan efek samping seperti iritasi. Penelitian ini bertujuan untuk menguji fisikokimia sabun cair dan mengetahui efektivitas antibakteri dengan menguji daya hambat sabun cuci tangan cair arang aktif batok kelapa terhadap pertumbuhan S. aureus. Penelitian ini menggunakan metode eksperimental dengan variasi konsentrasi arang aktif batok kelapa F1 (1%), F2 (2%), F3 (3%) dan F4 (4%). Sediaan sabun cair arang aktif batok kelapa dianalisis secara fisikokimiawi meliputi uji stabilitas busa, bobot jenis, viskositas, dan pH. Uji daya hambat bakteri dengan metode disc diffusion. Penelitian menunjukkan bahwa formula sabun cuci tangan cair arang aktif batok kelapa memiliki nilai uji fisikokimiawi yang telah memenuhi standar SNI, pH 5,54-5,65; bobot jenis 1,02-1,06; stabilitas busa and 40,5 mm-47,75 mm, and viscosity 876,63 cPs-1662,64 cPs. Pada F2 (2%) memiliki efektivitas paling baik terhadap zona hambat untuk Staphylococcus aureus sebesar 30,85 mm. Sabun cuci tangan cair arang aktif batok kelapa dapat digunakan sebagai sabun antibakteri yang memiliki kemampuan dalam menghambat pertumbuhan Staphylococcus aureus.
Analisis Biaya Operasi Teknik Off-pump CABG dibandingkan On-pump CABG Pasien BPJS Penyakit Jantung Koroner dengan Fungsi Jantung Buruk di Rumah Sakit Jantung Harapan Kita
Authors: Aris Aris , Anggriani Yusi , Dudy Arman Hanafy , Ruru Yacob
Published: February 2022

Coronary heart disease (CHD) is a heart disease that is mainly caused by narrowing of the coronary arteries due to atherosclerosis or spam or a combination of both. In CHD patients who continued therapy, coronary artery bypass surgery can be performed Off-pump CABG or On-pump CABG, with hearts function poorly with LEF < 30 % at risk and a higher complication which results in increased costs. The research is aimed to analyze the operating cost Off-pump CABG technique compared to the On-pump CABG technique in patients with BPJS coronary heart disease with poor heart function in Rumah Sakit Jantung dan Pembuluh Darah Harapan Kita on period January – December 2015. Patient sample selection is done in the installation of medical records with the diagnosis of CHD undergoing coronary artery bypass surgery technique Off-pump CABG and On-pump CABG. Data retrieval costs of pre-operatives, peri-operatives, and post-operative. This research conducted prospectively. Data were analyzed using the Kolmogorov test, Mann Whitney test, and Kruskal Wallis test. Research results obtained from a total of 70 patients with each of the 35 patients who underwent Off-pump CABG and On-pump CABG. The average cost of technique operation Off-pump CABG amounted to Rp.85,812,864. The average cost of technique operation on-pump CABG amounted to Rp.105,480,363. Operation margin amounted to Rp. 19,667,499. Mann-Whitney test shows different averages with p-value=0,006, then there is a significant difference between the two groups. Comparison of the rates for the Ina-CBGs surgery techniques Off-pump CABG an average of Rp.141,747,683, different of Rp. 55,934,819. Of the rates for the Ina-CBGs surgery techniques on-pump CABG an average of Rp. 138,782,251, different of Rp. 33,301,888. Kruskal Wallis test shows a different averages with p-value=0,000, then there is a significant difference between the two groups. Operating cost Off-pump CABG technique is lower than of On-pump CABG surgery technique. Operating cost Off-pump CABG technique and On-pump CABG lower than tariff Ina-CBGs.
Colocasia esculanta L. (Talas): Kajian Farmakognosi, Fitokimia dan Aktivitas Farmakologi
Authors: Ladeska Vera , Am Rino Andriano , Hanani Endang
Published: February 2022

Taro plant (Colocasia esculenta L.) belongs to the Araceae family is one of the most widely grown plants in Indonesia, and is widely used as a food ingredient. In some countries this plant has long been used for traditional medicine. Until now, there has not been found a review of taro plants that includes biology, chemical content and properties. This study aims to review the taro plant (C. esculenta L.) in terms of pharmacognosy, phytochemical and pharmacological properties. The research is compiled based on journals that have been collected by both national and international journals. The results of the study stated that in Indonesia, various types of taro are grown. In the stems, leaves and tubers there are various chemical compounds, depending on the planting area. Taro has activity as an antioxidant (medium category), antimicrobial, antibacterial.
Hubungan Durasi Terdiagnosis Diabetes Melitus Tipe 2 dan Kejadian Hipertensi dengan Terjadinya Makula Edema pada Retinopati Diabetik
Authors: Tandiarrang Grace Pisca , Fatmawati Nur Khoma , Danial Danial
Published: February 2022

Diabetes Melitus merupakan penyakit tidak menular yang saat ini merupakan ancaman kesehatan global karena insiden diabetes melitus yang terus meningkat. Insiden diabetes melitus yang terus meningkat akan diikuti oleh meningkatnya komplikasi dari diabetes melitus. Makula edema merupakan komplikasi dari retinopati diabetik yang menjadi penyebab utama terjadinya kebutaan pada penderita diabetes. Faktor-faktor yang menjadi penyebab makula edema yaitu lama menderita diabetes, hipertensi, peningkatan HbA1c dan hiperlipidemia. Tujuan dari penelitian ini adalah mengetahui hubungan antara durasi terdiagnosis diabetes melitus tipe 2 dan kejadian hipertensi dengan terjadinya makula edema pada retinopati diabetik.  Desain dalam penelitian ini menggunakan studi potong lintang dengan metode analitik observasional. Penelitian dilakukan di Sumatera Eye Centre (SMEC) Samarinda pada bulan Januari hingga Februari 2010 dan menggunakan metode total sampling. Analisis bivariat dilakukan menggunakan uji chi-square. Hasil analisis diperoleh adanya hubungan antara durasi terdiagnosis diabetes melitus tipe 2 ( p = 0,001) dan kejadian hipertensi ( p= 0,000) dengan terjadinya makula edema pada retinopati diabetik.
Pengaruh SSRIs Untuk Meningkatkan Independensi Fungsional Pada Pasien Depresi Pasca Stroke
Authors: Salim Winda Puspita , Hutahaean Yetty Octavia , Sihotang Fransiska Anggreni
Published: February 2022

Post-stroke depression has a negative impact on the functional independence of patients carrying out daily activities. Selective serotonin reuptake inhibitors (SSRIs) are a class of antidepressants that are recommended as the first-line therapy for post-stroke depression because of their favorable tolerability profile. This literature review is intended to present a new insight about the effect of SSRIs in increasing the functional independence in patients with post-stroke depression. We applied a qualitative research design using two notable databases: PubMed and Google Scholar. Only references written in English were used in this paper. We also limited the publication year of journals from 2010 to 2020. From the results of journal searches, we found around 52.984 journals. However only 5 were included that met the inclusion criteria which were: (1), Randomized Controlled Trial (RCT) that tested the benefits of SSRIs treatment in post-stroke depression patients compared to other antidepressants or other treatment modalities; and (2) provided with the outcome measure of functional independence. In conclusion, we believe that SSRIs have an effect on improving functional independence in post-stroke depression patients. SSRIs have also been shown to have positive effects with various combinations of non-pharmacological therapeutic modalities as their support.
Hubungan Status Gizi, Umur, Jenis Kelamin dengan Derajat Infeksi Dengue pada Anak di RSUD Abdul Wahab Sjahranie Samarinda
Authors: Kharisma Putri Lintang , Muhyi Annisa , Rachmi Eva
Published: February 2022

Dengue virus infection can manifest from mild to severe, which are undifferentiated fever, dengue hemorrhagic fever (DD), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS), respectively. Mild and severe dengue infection is difficult to distinguish early in the course of the disease, and the clinical course is also difficult to "predict". Therefore, indicators were needed to predict the degree of dengue virus infection, thus appropriate treatment can be given. The study was aimed to determine the association of nutritional status, age, and sex with the degree of dengue infection in children. This study was an analytic observational study with a cross-sectional design. The samples were pediatric patients (0-18 years), who have been diagnosed with dengue virus infection and were hospitalized at the Abdul Wahab Sjahranie Hospital Samarinda in 2019. Purposive sampling technique was used to appointed 88 patients. The data obtained from the medical records. The bivariate association was statistically analyzed with chi-square test. The result showed a significant association between sex (p = 0.041) with the degree of dengue infection in children. Meanwhile nutritional status (p = 0.127) and age (p = 0.077) had no significant association with the degree of dengue infection in children. In conclusion, sex might serve as a predictor of the degree of dengue infection in children, in which male is more susceptible to worse manifestations.
Penggunaan Antibiotik Restriksi pada Pasien Ulkus, Abses dan Batu Kandung Kemih di Bangsal Bedah RSUD H. Abdul Manap Kota Jambi Periode 2017-2019
Authors: Ningsih Satiya , Andriani Yuni , Rahmadevi Rahmadevi
Published: February 2022

Penggunaan antibiotik yang tidak sesuai meningkatkan kasus terjadinya resistensi antibiotik. Pembatasan jenis antibiotik atau antibiotik restriksi merupakan salah satu strategi untuk mengurangi kejadian resistensi antibiotik, menekan biaya antibiotik serta menurunkan pemakaian antibiotik yang berlebihan. Tujuan penelitian ini adalah untuk mengetahui persentase penggunaan antibiotik restriksi pada pasien Ulkus, Abses dan Batu Kandung Kemih di Bangsal Bedah RSUD H. Abdul Manap Kota Jambi Periode 2017-2019. Penelitian ini menggunakan desain penelitian non-eksperimental yang bersifat deskriptif. Pengambilan data dilakukan secara restrospektif dengan teknik pengambilan sampel secara purposive sampling. Hasil perolehan sampel pada penelitian ini sebanyak 43 sampel yang memenuhi kriteria dari 135 pasien populasi diantaranya dengan diagnosis ulkus 15 sampel terdiri dari 40% pasien laki-laki dan 60% pasien perempuan, 40% usia 56-65 tahun dengan komorbid diabetes melitus tipe 2. Pasien dengan diagnosis abses 18 sampel terdiri dari 61,1% pasien laki-laki dan 38,9% pasien perempuan, 27,8% usia 36-45 tahun dengan komorbid sepsis dan diabetes melitus tipe 2. Pasien dengan diagnosis batu kandung kemih 10 sampel terdiri dari 30% pasien laki-laki dan 70% pasien perempuan, 60% usia 46-65 tahun. Selama periode 2017 sampai 2019 untuk pasien ulkus, abses dan batu kandung kemih menggunakan 2 jenis antibiotik restriksi yaitu ciprofloxacin dan levofloxacin. Pada pasien ulkus, abses dan batu kandung kemih jumlah penggunaan antibiotik restriksi yang banyak digunakan ialah antibiotik ciprofloxacin dengan persentase 21%, sedangkan penggunaan levofloxacin dengan persentase sebesar 10%. Kesimpulan dari penelitian ini adalah penggunaan antibiotik restriksi periode 2017-2019 pada diagnosis ulkus yaitu 41%, 35,7% dan 25%. Pada diagnosis abses yaitu 40%, 25% dan 35,2% serta pada diagnosis batu kandung kemih yaitu 18,1%, 33,3% dan 20%.