bluuebunny/crossref_metadata_2025 huggingface dataset:
“I hear you like bad girls? I’m bad at everything”: a British-Spanish cross-cultural analysis of humour as a self-presentation strategy in Tinder profiles
Authors: Cantos-Delgado Clara , Maíz-Arévalo Carmen
Published: September 2023

This article explores humour employed as a self-presentation device in the biography section of Tinder profiles belonging to heterosexual users (male and female) in their 20s based in Spain and the United Kingdom. The main purpose of this investigation is to find out if male or female users are more prone to resorting to humour in their Tinder profiles and if the culture within which this interaction takes place also affects the frequency of use of humorous remarks. More specifically, we intend to answer the following research questions: (i) To what extent does gender influence the use of humour as an online self-presentation strategy?,  (ii) To what extent does the users’ cultural context play a role in the frequency and way humour is employed? To that purpose, a total of 455 Tinder profiles from both Spanish (224) and UK (231) users was gathered with the help of a bot, Tinderbotz, and it was then analysed quantitatively and qualitatively with the assistance of the software program Atlas.ti. The results show that UK users favour humour as a self-presentation strategy in a significantly higher percentage than their Spanish counterparts, independently of their gender. Thus, while Spanish-speakers may regard humour as a risky mechanism that can backfire, UK users embrace it as part of the Anglo-Saxon ethos of not taking oneself too seriously.
Forms and functions of jokes disseminated during the Covid-19 pandemic in Jordan
Authors: Tawalbeh Ahmad , Abu-Elrob Rula , Al-Saidat Emad , Alenazy Mamdouh
Published: September 2023

People in Jordan have suffered the effects of the Covid-19 pandemic. The Jordanian government took some pre-emptive measures to curb the spread of the virus, including the announcement of indefinite curfew and nationwide strict lockdown. Humorous texts appear to be the people’s key to escape from life stress, minimise the pressure of unpleasant situations and increase pleasure. Jordanian humour attracts our attention to find out what it does during the Covid-19 pandemic and investigate its structure. To pursue this aim, a sample of 50 jokes and memes were collected from Facebook and WhatsApp in 2020 and analysed using the General Theory of Verbal Humour (GTVH). The researchers conducted a systematic and detailed analysis of the data relying on the six knowledge resources postulated by the GTVH, which are script opposition, logical mechanism, situation, target, narrative strategy and language. The analysis showed that humour can be viewed as a tool to release the tensions caused by Covid-19 restrictions on mobility and lockdown. It also revealed the people’s comments on different aspects of their life during the pandemic, including but not limited to social contact, economic status and education. In most of the analysed texts, humour is playful and serves the function of decommitment. This study offers insights into Arabic humour discourse, showing how jokes may serve the emerging context and encourage conducting studies on humorous texts in various settings to show what roles they would play.
Visão além da aparência: um diagnóstico estratégico da Capillari For Men no mercado de cosméticos masculinos
Authors: Reis Marcilene Coelho , Silva Cícera Maíra da Conceição , Roberto José Carlos Alves , Pinto Junior José Roberto Lira
Published: September 2023

Este artigo científico apresenta um diagnóstico organizacional da empresa Capillari For Men, uma empresa de cosméticos masculinos. Através de uma metodologia qualitativa multidimensional, envolvendo revisão bibliográfica, questionários, entrevistas e análise documental, foram identificados os pontos fortes e áreas de melhoria da empresa, bem como as oportunidades e desafios no mercado de cosméticos masculinos. O diagnóstico revelou que os setores Operacional e Financeiro apresentam alto desempenho, enquanto os setores de Marketing e Administrativo estão em níveis intermediários. Por outro lado, o setor de Recursos Humanos apresentou o menor desempenho, indicando a necessidade de atenção e melhorias nessa área. A análise externa identificou a possibilidade de parcerias estratégicas com outras empresas do mesmo segmento como uma oportunidade sinérgica para ampliar o mercado. Porém, a concorrência de outras lojas oferecendo produtos similares representa uma ameaça que requer a busca por diferenciais competitivos. Com base nos resultados, foram propostas estratégias para o sucesso sustentável da Capillari For Men. Investir na gestão de Recursos Humanos é fundamental para promover um ambiente de trabalho saudável e produtivo, com programas de qualidade de vida e capacitação profissional. Aproveitar a tendência crescente de cosméticos masculinos com produtos inovadores e específicos, parcerias estratégicas para expansão, liderança visionária, e gestão de mudanças, além de investir em bem-estar dos colaboradores, prepara a Capillari For Men para enfrentar desafios, ser referência no mercado e alcançar sucesso sustentável.
Unsung Heroes: A Phenomenological Study on Experiences and Struggles of Special Education Language Teachers
Authors: Lariba Feliceto Jr. V.
Published: September 2023

Aim: To document the experiences of Special Education (SPED) language teachers in their language teaching, collaboration with parents and interaction with fellow educators in mainstream education.

Study Design: The study used Qualitative method.

Place and Duration of Study: Monkayo Central Elementary School, Compostela Valley, Philippines during the school year 2019-2020.

Methodology: The participants were five male and female Special Education teachers. They used purposive and snowball sampling. Information was gathered through in-depth interviews using validated researcher-made questions written in multilingual (English, Tagalog, and Cebuano). The information was analyzed thematically.

Results: The special Education teacher dealt with various areas of language learning depending on the learner's impairment. Teachers also improvised approaches and developed coping mechanisms in dealing with experiences. This research provided implications to increase efficiency in language teaching in Special Education programs; increase parents' engagement in school activities and programs; and improve special education and mainstream education teachers' interaction.

Conclusion: In conclusion, the research highlights the significant challenges faced by SPED language teachers in educating learners with special needs. Despite these obstacles, SPED teachers have demonstrated remarkable resilience, employing various coping mechanisms and fostering cooperation with parents and mainstream teachers. Their unwavering commitment, patience, and positivity exemplify their dedication to providing the best learning opportunities for their special needs students
A Rare Case of Kikuchi-Fujimoto Disease in an Indian Female
Authors: Darda Shubham , Majmundar Aarjuv , Upadhyay Puneet , Nouni Harshita H. , Lakhani Sucheta , Lakhani Jitendra D.
Published: September 2023

Kikuchi-Fujimoto disease is a self-limiting illness characterised by non-specific symptoms, most commonly reported symptoms being fever and lymphadenopathy. Unknown in its cause, Kikuchi-Fujimoto disease (KFD) is a benign, uncommon disorder usually presenting under the age of 30 years in women. This disease is mainly seen in Asian population mainly in Japan but it is rare in Indian population. The etiological cause of this disease remains unknown. This condition needs to differentiated from other closely resembling conditions such as tuberculosis, lymphoma, Systemic Lupus Erythematosus (SLE) and adenocarcinoma. The physician needs to be aware about this condition to avoid misdiagnosis and improper treatment. This case report is about a female of age 26 years who was diagnosed as having Kikuchi Fujimoto Disease on the basis of clinical and biopsy findings.
Inverted Sinonasal Papilloma: Update and Literature Review
Authors: Awosusi Babatope Lanre , Rahman Adam Tolulope
Published: September 2023

Inverted sinonasal papilloma is a benign neoplasm that usually affects the intra-nasal cavity and adjacent paranasal sinuses. Inverted papillomas have three unique features that distinguishes them from other sinonasal tumors including; a propensity for local destructive growth, a high rate of recurrence and risk of malignant transformation. The reported yearly incidence is about 0.6 to 1.5 cases per 100,000 people per year and they usually account for 0.5% to 4% of all nasal tumors. They occur at the following locations; both lateral nasal walls, ethmoidal cells, maxillary sinus, the frontal sinus, sphenoid sinuses and the nasal septum in decreasing order. It occurs most commonly in the fifth and sixth decades of life with a male-to-female ratio of 2-3:1. Inverted papilloma can arise from the entire Schneiderian membrane and molecular genetics have confirmed that it is an actual neoplasm that arises from a single progenitor cell. Most cases are diagnosed from clinical history and thorough physical examination. However, complete removal of all affected tissue with thorough histopathological evaluation is recommended to ensure a correct diagnosis. While there is yet no established pathognomonic histopathological feature to predict recurrence with all certainty, there is ongoing investigation for predictive markers of recurrence. Smoking seems to be a recognized risk factor for developing multiple recurrences and there is evidence that the presence of HPV serotypes 16 and 18 could be predictive of malignant transformation. The main aim of treatment is to achieve compete surgical resection and to prevent recurrence and malignant transformation. A period of clinical follow up is recommended after treatment. The aim of this review is to provide a comprehensive and updated overview of the clinical presentation, diagnosis, management and prognosis of this unique lesion.
Quantifying Trends of Historical Climatic Variables in the Jessore Region of Bangladesh
Authors: Nuruzzaman Md. , Soni Most. Sifat Muntaha , Rana Md. Shohel , Haq Ahsanul , Molla Md. Matiur Rahman
Published: September 2023

The aim of the study was to detect trends in salient key climate variables in the Jessore region of Bangladesh for the years 1985–2014, and the data was collected from the Bangladesh Meteorological Department (BMD). Annual rainfall, annual maximum temperature, and annual cloud coverage were analyzed using the non-parametric Mann-Kendall test, linear regression, and LOWESS curve to detect trends in the series. The rainfall and cloud coverage showed a decline trend at a rate of (4.50 mm/year; 45.02 mm/decade) and (0.045 octas/year; 0.45829 oktas/decade), respectively, whereas temperature manifested an increment trend (0.0285°C/year; 0.2854°C/decade), where cloud coverage was the only significant variable. The structural breakdown point was found using the graphical method and the Chow test, which showed in 2004 that both the series containing breakdown points and cloud coverage exhibit statistical significance.
Navigating the Realm of Product Promotion for Local Chocolates
Authors: Lirag Ma. Teresa B. , Edmundo B. Casaul Jr  , Ramirez Ramona Isabel S.
Published: September 2023

The Philippines is starting to have strong gains in the chocolate confectionery with the steady increase in demand for local chocolates. A study was conducted to determine the promotional media preference and strategies for creating awareness of the local chocolate developed by the university and identify the barriers in the promotion and marketing sphere. A total of 65 respondents were randomly chosen and a structured questionnaire and focused group discussion was undertaken to gather data from the field. Results of the study showed that various marketing technologies and product promotions are preferred for introducing the chocolate developed by the university. Consumers had outgrown their desire to buy chocolates in the traditional market outlet of souvenir shops and utilization of innovative social media marketing is highly predominant. Likewise, inclination in the use of digital platforms has been established and widely employed resulting to the dwindling utilization of traditional media. Towards this end, it is crucial to identify future activities that will make use of digital technology to push and promote the local chocolate to increase its competitiveness, continuous trainings must be provided to entrepreneurs on online marketing strategies, provision of financial support must be continued for upscaling the product and consumer-centered research must be continuously conducted to address the diverse needs of the consumers when new products are introduced in the market.
Effects of Source and Rates of Potassium Fertilizer on Yield Traits and Potassium Use Efficiency of Potato in a Kenyan Ferralsol
Authors: Oketch Anthony O. , Ngeno Jonah K. , Ngode Lucas K. , Chiveu Josiah C. , Churu Harrison
Published: September 2023

Aims: Potassium (K) is one of the nutrient elements taken up in large amounts by potatoes,                  yet there is little research output on K fertilization of the crop in Kenya, due to the assumption                  that its natural soil reserves are sufficient for the production of most crops. The study objective                was to determine the influence of two K sources (muriate of potash – KCL and sulphate of potash – K2SO4) on K use efficiency and tuber yield components of potatoes in one agro-ecological zone               of Kenya.

Place and Duration of Study: The experimental site was the University of Eldoret farm in Kenya, located at latitude 0o574942’ N and longitude 35o300772’ E, during the middle - second rains season (S1) and middle rains season (S2) of 2020 and 2021 respectively.

Methodology: Treatments were: 0 kg K ha-1 (control), 60,120,180 and 240 kg K ha-1 in S1 and 0, 30, 60, 90, 120 and 180 kg K ha-1 in S2, supplied in the form of KCL and K2SO4. Treatments were laid in a Randomized Complete Block Design in 2x5 and 2x6 factorial arrangements in S1 and S2 respectively. The potato variety planted was Destiny. Data collected included: Agronomic efficiency of K (AEK,), total tuber yield, two categories of seed yield (Size 1 tubers with diameters of 28- 45 mm; Size 2 tubers with 46 - 60mm diameter), total seed yield and ware yield (tubers with diameters over 60mm).

Results: During the drier S1, the application of 120 kg K ha-1 in the form of K2SO4 significantly (P < .001) increased the yield of size 1 tubers, total seed yield and total tuber yield. The total tuber yield increment from this K rate was only 12.6 % of the varietal potential yield, and its AEK was 0.042 tonnes of tubers kg-1 K. Therefore its application may not be economically viable. During the moisture-sufficient S2, all K fertilizer treatments in the form of KCl and 90 kg K ha-1 in the form of K2SO4, contributed a yield increase of 58.1 - 68.6% and slightly exceeded varietal yield potential. Additionally, 30 kg K ha-1 of KCL gave the highest AEK of 0.5 tonnes of tubers kg-1 K and consistently enhanced the yield of all potato sizes, except size 1.

Conclusion: Under similar ecological conditions as S2, potato farmers can achieve the highest AEK and potential tuber yield with the application of 30 kg K ha-1 of KCL. However, more trials on K nutrition in potatoes need to be done in diverse environments.
Assessment of Biodrainage Potential of Existing Plant Species Along the Sewage Drains of Vedapatti Drainage Stretch, Coimbatore, Tamil Nadu, India
Authors: Vigneshwar P. Sundra , Bharani A. , Prasanthrajan M. , Kumar V. Ravi , Vijayalakshmi D.
Published: September 2023

The proper disposal of manufacturing and consumer waste, including sewage sludge, is one of the numerous environmental issues facing today's society. In addition to posing serious health concerns to humans, anthropogenic activities are a major source of environmental pollution and can result in an overabundance of pollutants entering the terrestrial ecosystem. The goal of the current study was to determine how existing tree and plant species near sewage drains were affected by the bioaccumulation of carcinogenic metals (Cd, Ni, Co, and Cr) together with other heavy metals. These heavy metals found in the sewage are hazardous to the health of both people and the environment. To further understand how well these plant species adapted to the metal-contaminated soil, many biological parameters, including stomatal density, leaf length, leaf area index, and stress hormone levels, were investigated. For every species included in the study, soil samples were taken near the sewer drains and the rhizosphere. The plant species' leaves and roots (where feasible) were also harvested. To check for metal buildup in the wood, various tree species had their trunks harvested. All of these samples go through an acid digestion process using an aquaregia combination. Following digestion, the samples are examined using Microwave Plasma Atomic Emission Spectroscopy (MP-AES) for the presence of heavy metals. In this study, we briefly address the findings on the accumulation of heavy metals by certain plant species.
In vivo Bio-efficacy of Fungicides and Antagonists for the Management of Target Leaf Spot of Soybean [Corynespora cassiicola (Berk. and Curt.) Wei]
Authors: Hiremath Ishwari G. , Huilgol Shalini N. , Hegde Yashoda , Priyanka K.
Published: September 2023

Foliar diseases cause major qualitative and quantitative yield loss in soybean, among which target leaf spot of soybean caused by Corynespora cassiicola is one of the constraints. Hence, management of this disease is much needed effort. Thus the present investigation was carried out for management of the disease under field condition using fungicides and bioagents that were effective in inhibiting the pathogen under in vitro studies. Among the different treatments evaluated, seed treatment with (pyraclostrobin 5% + thiophanate methyl 45%) @ 2 ml/kg seed followed by spray with (tebuconazole 50% + trifloxystrobin 25%) @ 0.05% at 55 and 75 days after sowing (DAS) recorded the least disease severity of 2.23 percent with higher seed yield (17.20 q/ha) and test weight (17.41 g) as compared to untreated check which recorded disease severity of 27.50 percent. Apart from the target disease, other diseases like rust, anthracnose and Alternaria leaf spot were also take care in the same treatment. Use of fungicides for the management of disease in the absence of resistant genotypes is an old practice and it is one of the best options when there is outbreak.
Advancing Integrated Pest Management: Utilizing Pheromone Traps for Population Monitoring of Plutella xylostella in Cole Crops
Authors: Zahoor Sobiya , Pathania S. S. , Ali Iqra , Anees Mehreen , Ayoub Liyaqat , Kishore Gayathri
Published: September 2023

Plutella xylostella, commonly known as the diamondback moth poses significant challenges to Cole crops, impacting their growth and ultimately affecting yields. Its rapid reproduction coupled with its ability for developing pesticide resistance has elevated the diamondback moth to a critical concern for farmers and agricultural systems worldwide. The adult population of Diamondback moth was thus monitored during two cropping seasons (Kharif and Rabi season) at three locations viz., Vegetable Experimental Field, Faculty of Horticulture, SKUAST-K, Shalimar, Urban Technology Park, SKUAST-K, Habbak and Ichgam village in district Budgam using two different Plutella xylostella synthetic sex lures (SKUAST-K and Chipku lures). During Kharif season, the adult diamondback population was monitored from 18th to 28th SW with a maximum trap catch in the last week of June (26th SW) at Shalimar; whereas, both in Budgam and Habbak, the highest trap catch was in first week of June (23rd SW). However, in Rabi season, the adult population was monitored from 34th to 44th SW; the highest adult trap catch was in third week of September (38th SW) at Shalimar, though, in Budgam and Habbak, the moth catch peaked to maximum collection in first and second week of October (40th and 41st SW), respectively. During both the seasons and at all the locations, SKUAST-K lure proved more efficacious than Chipku lure. Besides, simple correlation analysis revealed that maximum temperature had positive and non-significant correlation with adult moth catches; conversely, the rainfall and relative humidity was negatively correlated and non-significant with P. xylostella adult trap catches throughout both observed seasons.
Effect of Potassic Fertilizer, FYM and Vermicompost on Growth Parameters, Yield Attributes and Yield of Pigeon Pea (Cajanus cajan) Crop in Chitrakoot Area
Authors: Bhimte Sakshi , Sirothia Pawan , Mishra Ashutosh , Singh Opendra Kumar , Mishra U. S.
Published: September 2023

A field experiment was conducted during Kharif season of 2022-2023 at Rajoula Agriculture farm, of Mahatma Gandhi Chitrakoot Gramodaya Vishwavidyalaya Chitrakoot, Satna (M.P.) to evaluate the effect of potassic fertilizer, FYM and vermicompost on growth parameters, yield attributes and yield of pigeon pea. The present experiment having 11 treatment combinations replicated thrice in randomized block design. Pigeon pea variety Rajeshwari Phule-12 was grown with recommended agronomic practices. On the basis of the results emanated from present investigation, it could be concluded that application of T11 [100 % N & P, K- 0 % + 100 % K through Vermicompost] significantly recorded maximum growth parameters such as plant population plot-1 (138.42), plant height (211.38 cm), number of leaves (208.6) and number of branches plant-1 (32.8) and maximum yield attributing characters such as number of pod plant-1 (103.6), number of seed pod-1 (4.4) and seed index (9.68 g).  The result showed highest grain yield (17.69 q ha-1) and straw yield (52.64 q ha-1), with 100% RDF + soil application of treatment T11 [100 % N & P, K- 0 % + 100 % K through Vermicompost] in comparison to all the treatments.
Assessment of Genetic Diversity of Rice (Oryza sativa L.) under Prayagraj Agro-climatic Conditions
Authors: Tarunum Shaik Suhana , Lal Gabrial M. , Lavanya Gera Roopa
Published: September 2023

The goal of the current study was to assess the genetic variability parameters and genetic diversity in 40 rice genotypes for 13 quantitative traits in the Kharif, 2022 Season at the field experimentation center, Department of Genetics and Plant Breeding, Naini Agricultural Institute, Sam Higginbottom University of Agriculture Technology and Sciences, Uttar Pradesh. Analysis of variance indicated highly significant differences among the genotypes for all the traits. Considerable variability existed among the genotypes for all the characters studied. It is concluded that among 40 genotypes of rice, Nellore Dhanyarasi showed early flowering (77 days), IR-64 had characters like early maturity (108 days), high grain yield per plant is seen in Shuats Dhan-6 (62.1 g), JHARA SEL showed high plant height (185 cm) and high biomass is seen in Shuats Dhan-6 (123.6 g), Swathi showed high panicle length (43.7 cm). Highest GCV and PCV were depicted for grain yield per plant, biological yield, harvest index and number of spikelets per panicle. The highest heritability was observed for Grain Yield per Plant followed by Harvest Index, Flag Leaf length, Biological Yield and Number of Spikelets per Panicle. The Genetic Advance in per cent of mean is high for grain yield per plant, biological yield, harvest index and number of Spikelets per Panicle. Based on D2 values, 40 genotypes grouped into 7 clusters. Among 7 clusters, cluster I had a greater number of genotypes (26) followed by cluster II (8), III (2), IV, V, VI andVII (1) genotype each. Cluster VI and cluster III (365.72) followed by cluster VII and cluster V (363.6), were most diverse from each other and the genotypes included in these clusters provide a broad spectrum of variability in segregation and may be used as parents in the future hybridization programme to develop desirable genotypes for grain yield improvement in rice genotypes. The trait Grain yield per hill had maximum contribution towards to genetic divergence followed by biological yield, Harvest Index, Test Weight. Therefore, all these characters should be given due consideration during selection for crop improvement.
Jogos de matriz africana e afro- brasileira: ecoando cantigas e semeando potencialidades para o ensino de química
Authors: Muller Lucas , Cleophas Maria das Graças
Published: September 2023

Este artigo emerge à luz das inquietações que pairam no universo educacional acerca do privilégio epistêmico e/ou currículo eurocêntrico. Ele traz algumas reflexões críticas, com o intuito de contribuir frente ao rompimento de discursos e silenciamentos convenientes, ao considerar a operacionalização da Lei no 10.639/2003. Portanto, objetiva desconstruir discursos hegemônicos sobre as contribuições dos povos africanos e afro- -brasileiros para a origem de jogos no cenário nacional, sobretudo destacando caminhos profícuos para a exploração das potencialidades dos jogos maculelê, capoeira, jongo e mancala no ensino de química em diferentes níveis educa- cionais. Para tanto, apresentamos as raízes ancestrais de jogos oriundos das matrizes africanas e afro-brasileiras para o contexto educacional, e apontamos as potencialidades sobre o seu uso, além de traçar combinações de ações relacionadas a sua dinâmica com outras estratégias didáticas indispensáveis para sua aplicação ao ensino de química.
Adaptação ao ensino superior: os domínios e os três tempos de afiliação
Authors: Gazar Thalita Nascimento , Figueiredo Santos Iriart Mirela
Published: September 2023

Com a democratização do acesso ao ensino superior, surgiu o interesse de investigar a adaptação de jovens oriundas de classes populares ao contexto universitário. Assim, objetivou-se caracterizar o perfil de 26 uni- versitárias do curso de Licenciatura em Pedagogia da Universidade Estadual de Feira de Santana no interior da Bahia, e as particularidades interpessoais, acadêmicas e vocacionais durante os três tempos de adaptação. Trata-se de uma pesquisa de campo, do tipo descritiva, a partir de levantamento de dados com uso de questionário. A análise dos dados se deu de forma quantitativa a partir do programa SPSS, versão 26, a partir de frequências absolutas e relativas. As participantes foram mulheres entre 18 e 23 anos, negras e mo- radoras de Feira de Santana, em sua maioria. No domínio interpessoal, elas demonstraram bom convívio e facilidade para se comunicar com colegas, pouca interação com docentes e desagrado por estar na universidade sem aula. Quanto ao domínio acadêmico, apresentaram satisfação com o curso escolhido, cansaço para frequentar aulas e pouco tempo de lazer. No domínio vocacional, a maioria das participantes respondeu imaginar boas perspectivas profissionais e boa inserção no mercado de trabalho, mas não souberam se iriam obter reconhecimento social e financeiro que o curso escolhido poderia lhes trazer. Conclui-se que na dinâmica de adaptação, houve equilíbrio no jogo de forças que dificultam ou facilitam a afiliação. Os pares mostraram- -se um suporte afetivo positivo no processo, enquanto a comunicação com professores e o suporte institucional precisavam ser fortalecidos para garantir um melhor engajamento estudantil.
A queixa escolar como dano secundário: um estudo de caso sobre aquisição da escrita
Authors: Graboski Camylla , Peixoto Carvalho Bruno
Published: September 2023

Este estudo é síntese de trabalho realizado no Estágio Obrigatório Curricular em Psicologia e Educação no curso de Psicologia da Universida- de Federal do Paraná. As intervenções foram realizadas na modalidade de atendimento da Orientação à Queixa Escolar (OQE), em uma perspectiva vigotskiana. A intervenção foi realizada com Luís, 11 anos, matriculado na rede pública de ensino do estado, com queixas relativas à produção escrita, diagnosticado com dislexia e apresentando uma deficiência no metacarpo do quinto dedo (mindinho) de ambas as mãos. A intervenção com Luís ob- jetivou: investigar as condições em que se processou a aquisição da leitura e escrita na sua trajetória escolar; investigar o sentido da escrita em sua vivência escolar; e explorar alternativas junto à rede de relações escolares para a superação das dificuldades. A análise demonstrou que um elemento importante relativo às dificuldades de Luís com a escrita relacionava-se com a incapacidade de seu meio escolar em empregar instrumentos de exercício da atividade escrita que não envolvessem o manejo de lápis e papel, algo até então não considerado durante seu processo de escolarização. Com a introdução de um notebook, constatou-se que, apesar das dificuldades, Luís estava em um estágio mais avançado do processo de aquisição da escrita do que revelavam suas produções escolares. O uso do equipamento permitiu- -lhe um engajamento com a escrita menos preocupado com o controle do lápis (o que lhe produzia imenso desconforto) e mais atento ao sentido da escrita nas atividades escolares, servindo como um meio de compensação.
Os espaços de berçário em contexto de creche e o seu potencial educador
Authors: RUBENS ERICA , Rossi Fernanda
Published: September 2023

O objetivo deste estudo consistiu em identificar o estado da arte da produção acadêmica no que concerne aos espaços de berçário no contexto de creche, mediante estudo de revisão sistemática da literatura, bem como na análise dos resultados obtidos pelos estudos identificados. Constata-se que as pesquisas relacionadas acerca dessa temática, embora ainda pouco estudada, têm ganhado relevância no meio acadêmico-científico, sendo encontradas 29 publicações no período entre 2011 e 2020, sendo 24 inéditas, posto que algumas estavam relacionadas. Ao analisar os resultados de tais estudos, conclui-se que os espaços de berçário têm grande potencial como ferramenta pedagógica que possibilita a ação intencional do(a) educador(a) de forma a promover o desenvolvimento infantil, em suas variadas dimensões, tais como as motoras, sensoriais, simbólicas, lúdicas e relacionais. Ainda, foi possível constatar que esse potencial do espaço está presente nos documentos oficiais que contemplam as instituições de educação infantil, porém esse conhecimento ainda não alcança o cotidiano das creches.
Ensino Remoto Emergencial: a perda do sentimento de pertencimento à universidade
Authors: Castro de Moura Cavalcante Anne Victoria , Carneiro da Silva Alessandro , Beckmann de Castro Menezes Aline
Published: September 2023

O ensaio reflete sobre as repercussões na experiência estudantil do ensino superior – no que tange ao sentimento de pertencimento –, a partir da pandemia e instalação do Ensino Remoto Emergencial (ERE). O sentimento de pertencimento incorpora sentimentos de ser valorizado, incluído e aceito na universidade. Para cumprir o objetivo proposto, um referencial teórico da área foi articulado a relatos de discentes de graduação. Destacaram-se três dimensões – espaço físico, relação entre pares, e afetividade no ensino-apren- dizagem –, para serem analisadas. Consideramos que o empobrecimento das relações no contexto universitário impactou diretamente no sentimento de pertença dos discentes, entendido na literatura como fator intrínseco e inerente à saúde mental.
Patient‐Reported Fatigue Associated with Joint Histopathology in Rheumatoid Arthritis
Authors: Pearce‐Fisher Diyu , Smith Melanie H. , Mehta Bella Y. , Spolaore Edoardo , DiCarlo Edward , Sun Dongmei , Goodman Susan M.
Published: January 2025

Objective

Fatigue is important for patients with rheumatoid arthritis (RA) but is poorly understood. We sought to study associations of fatigue with clinical features, disease activity, and synovial histology.

Methods

Patients meeting the American College of Rheumatology/EULAR 1987 and/or 2010 RA criteria were recruited before elective total joint replacement. Demographics, RA characteristics, tender and swollen joints, erythrocyte sedimentation rate (ESR) and C‐reactive protein, and patient‐reported fatigue, categorized as mild, moderate, or severe, were collected. Hematoxylin and eosin stains of sectioned synovium were systematically scored by a pathologist. Relationships between fatigue and studied variables were evaluated with Kendall's tau. A directed acyclic graph (DAG) was used to illustrate associations of exposures, outcome variables, mediators, and confounders. Multivariable ordered logistic regression was used to further study associations.

Results

Of 160 included patients, 85.6% were women, with a median age of 63.5 (55.25–71.40) and mean disease activity scores in 28 joints using ESR (DAS28‐ESR) of 3.91 (SD 1.3). There were no differences in comorbidities across fatigue categories. Fatigue correlated with DAS28‐ESR, synovial lining hyperplasia (SLH), anxiety, depression, and pain. In the DAG, DAS28‐ESR was associated with fatigue, full mediation by pain, partial mediation by depression and anxiety, and confounding by female sex. SLH was independently associated with fatigue but did not confound the relationship between DAS28‐ESR and fatigue. SLH was affected by synovial lymphocytic inflammation. In multivariable models, female sex, DAS28‐ESR, and SLH were all associated with higher fatigue.

Conclusion

Although fatigue is associated with DAS28‐ESR, it is also associated with SLH independently of disease activity.
Pegloticase and Methotrexate Cotherapy in Patients With Uncontrolled Gout With Prior Pegloticase Monotherapy Failure: Findings of an Open‐Label Trial
Authors: Troum Orrin M. , Botson John K. , Obermeyer Katie , Chao Bo , Song Yang , Zarzoso Jennifer , Gutierrez Kjerstina , Verma Supra , Padnick‐Silver Lissa , LaMoreaux Brian
Published: January 2025

Objective

Patients with uncontrolled gout have few treatment options. Pegloticase lowers serum urate (SU) levels, but antidrug antibodies limit SU‐lowering response and increase infusion reaction (IR) risk. Methotrexate (MTX) cotherapy increases pegloticase response rates and lowers IR risk in pegloticase‐naïve patients. Therefore, the question of re‐treating patients with previous pegloticase monotherapy failure has arisen. The ADVANCE open‐label trial examined pegloticase plus MTX cotherapy efficacy and safety following pegloticase monotherapy failure.

Methods

Patients with uncontrolled gout (SU levels ≥6 mg/dL, oral urate–lowering therapy failure or intolerance, and ≥1 gout sign or symptom) who previously lost SU‐lowering response to pegloticase monotherapy were included. Key exclusion criteria were moderate‐to‐severe IR or anaphylaxis to pegloticase, MTX contraindication, immunosuppressant administration, glucose‐6‐phosphate dehydrogenase deficiency, and estimated glomerular filtration rate <30 mL/min/1.73m2. After a 6‐week subcutaneous MTX run‐in (at 25 mg/wk), patients entered 24‐week pegloticase (at 8 mg biweekly) plus MTX treatment. The primary end point was SU‐lowering response rate during month 6 (SU levels <6 mg/dL for ≥80% of weeks 20–24). Safety was assessed via adverse events (AEs) and laboratory monitoring.

Results

Eleven patients began pegloticase plus MTX treatment (91% male patients, mean age 58.6 ± 11.3 years, mean ± SD SU levels 8.5 ± 3.2 mg/dL, 91% tophaceous). Previous pegloticase course was 2 to 27 infusions, with the last infusion admins being a mean ± SD of 3.7 ± 2.4 years before. One patient (9%) maintained response during month 6; 10 patients prematurely discontinued treatment (loss of SU lowering [n = 8], IR [n = 2]). Eight patients (73%) experienced ≥1 AE, most commonly gout flare. All AEs were mild or moderate.

Conclusion

Pegloticase plus MTX response rate following failed monotherapy was lower (9% vs 71%) and IR rate was higher (18% vs 4%) than in pegloticase‐naïve patients. These findings demonstrate the challenge of overcoming established antipegloticase antibodies and emphasize the importance of initiating immunomodulation before the first pegloticase exposure.
High Kinetic Inductance in Platinum‐Coated Aluminum Nanobridge Interferometers
Authors: Nazhestkin Ivan A. , Bakurskiy Sergey V. , Neilo Alex A. , Tarasova Irina E. , Ismailov Nidzhat G. , Gurtovoi Vladimir L. , Egorov Sergey V. , Lisitsyn Sergey A. , Stolyarov Vasily S. , Antonov Vladimir N. , Ryazanov Valery V. , Kupriyanov Mikhail Y. , Soloviev Igor I. , Klenov Nikolay V. , Yakovlev Dmitry S.
Published: January 2025

The transport properties of a nanobridge superconducting quantum interference device made of Al/Pt bilayer have been studied. Measurement and approximation of the voltage‐field dependencies allow to estimate the inductance of the structure. It is found that this value significantly exceeds the expected geometric inductance and exhibits an atypical temperature dependence. To explain this effect, a microscopic model of electron transport in SN bilayers is developed, considering the proximity effect, and the available regimes of the current distribution are described. The measured properties may be indicative of the formation of high‐resistance aluminum with high values of kinetic inductance during the fabrication of Al/Pt bilayers.
Neutrophil Airfreighter Efficiently Delivers siRNA‐Loaded Nanocomplex to Mononuclear Phagocytes for Inhibition of mtDNA‐Induced Inflammation
Authors: Ren Mingxing , He Ping , Liu Fengyi , Li Yuzhou , Li Meng , Xiang Kai , Zhang Yining , Li Xinyi , Wu Tianli , Yang Sheng , Song Jinlin
Published: January 2025

The extensive intercellular material and information flow in the immune microenvironment is instructive to the development of targeted delivery strategies, but has received little attention previously. In this study, efferocytosis, an important link of material and information flow during inflammation, is creatively used to achieve a significant increase of targeted delivery efficiency. A tailored “neutrophil airfreighter” strategy is developed to deliver plenty of siRNA‐loaded nanocomplexes (FCM@siNPs) to mtDNA‐releasing sentinel mononuclear phagocytes (MPs) in vivo, providing them with immuno‐directed information. FCM@siNPs consist of siRNA‐loaded mesoporous silicon modified with engineered NIH3T3 cell membranes. Based on this innovative strategy, the delivery efficiency of FCM@siNPs to MPs is improved by 360% in vitro and 120% in vivo. FCM@siNPs could effectively inhibit periodontal inflammation in mice by precisely regulating the mtDNA‐induced inflammatory response in MPs. This study suggests the potential of the organismal material and information flow in the design of efficient targeted delivery strategies.
Wearable Haptic Feedback Interfaces for Augmenting Human Touch
Authors: Patel Shubham , Rao Zhoulyu , Yang Maggie , Yu Cunjiang
Published: January 2025

The rapid development of virtual and augmented reality has highlighted the growing need for haptic feedback interfaces, particularly in portable or wearable formats. These haptic feedback interfaces significantly enhance the immersive experiences of users across various domains, including social media, gaming, biomedical instrumentation, and robotics by utilizing sophisticated actuators to stimulate somatosensory receptors or afferent nerves beneath the skin, thereby creating tactile sensations. Despite the progress in various haptic feedback interfaces that employ diverse working mechanisms, each mode has limitations. This article comprehensively reviews the current state and potential opportunities of various haptic feedback interfaces with a particular focus on actuator technologies. Existing haptic feedback interfaces can be classified into three main categories: force‐based haptic feedback interfaces, thermal haptic feedback interfaces, and electrotactile haptic feedback interfaces.
Material Composition Gradient Controls the Autonomous Opening of Banksia Seed Pods in Fire‐Prone Habitats
Authors: Reppe Friedrich , Guiducci Lorenzo , Elbaum Rivka , Werner Peter , Dunlop John W. C. , Merritt David J. , Fratzl Peter , Eder Michaela
Published: January 2025

Plants possess intriguing mechanisms to cope with environmental stresses and disturbances, and respond to stimuli due to their sessile nature. Banksia attenuata, a tree or shrub species native to southwestern Australia, integrates numerous traits to persist and regenerate through reoccurring bushfires. A key trait of Banksia is that of serotiny: Plants can retain seeds for many years within the canopy protected inside durable seed pods (follicles), with seed release commonly triggered by the heat of bushfire, and subsequent rainfall. Here, we show that the tissue of the two follicle valves is arranged in layers, which not only counteract as a hygroscopic bi‐layer, but prevent delamination as their opposed physical properties converge toward the interface. Moreover, a shape‐memory effect of the active layer stores energy after the first opening step for the second opening step, ensuring delayed seed release only after the fire is extinguished. Detailed experiments reveal how structure, composition and physical properties of the tissue layers facilitate first longevity and later the complex autonomous seed release. Based on these findings, two numerical models illustrate the mechanics of the layers more deeply. These results highlight the importance of graded material properties for the function of natural actuators.
Beyond Solution‐Based Printing: Unveiling Innovations and Advancements in Solvent‐Free Printing Technologies
Authors: Doddapaneni V. Vinay K. , Song Chuankai , Dhas Jeffrey A. , Cheng Ningmo , Camp Isaac , Chang Alvin , Pan Changqing , Paul Brian K. , Pasebani Somayeh , Feng Zhenxing , Sierros Konstantinos A. , Chang Chih‐hung
Published: January 2025

Vapor printing technologies are emerging as powerful tools for device fabrication due to their unique solvent‐free nature. In recent years, a few articles have been published to investigate these printing technologies for applications such as organic light‐emitting diodes (OLEDs), circuits, sensors, photodetectors, and drug screening. These printing technologies are physical vapor printing methods based on ablation, evaporation, and condensation. In this perspective, the advancement of vapor printing technologies is highlighted and introduce an additional approach enabling the chemistry of molecular precursors to be fully exploited dynamically. These additional concepts of vapor printing are introduced from the perspective of the printer's design and the development of process strategies with supporting original data. Furthermore, potential applications, challenges, and outlook are discussed. Specifically, this outlook appeals to researchers involved in nanostructured materials, semiconductors, catalysts, alloys, metals, polymers, functionally gradient materials, multi‐material structures, and additive manufacturing (AM) from academia and industries alike.
Endogenous Protein‐Modified Gold Nanorods as Immune‐Inert Biomodulators for Tumor‐Specific Imaging and Therapy
Authors: Fang Chunyan , Cai Yueming , He Cui , Li Ying , He Lei , Wang Xiaoyan , Lu Yong
Published: January 2025

Engineered modifications of nanomaterials inspired by nature hold great promise for disease‐specific imaging and therapies. However, conventional polyethylene glycol modification is limited by immune system rejection. The manipulation of gold nanorods (Au NRs) modified by endogenous proteins (eP@Au) is reported as an engineered biomodulator for enhanced breast tumor therapy. The results show that eP@Au NRs neither activate inflammatory factors in vitro nor elicit rejection of immune responses in vivo. Tumor‐specific eP@Au NRs exhibit a dual‐modal imaging capability and trigger a mild photothermal effect under near‐infrared light irradiation, enabling highly efficient imaging and therapy of tumors. Transcriptome sequencing and confirmatory experiments reveal that the antitumor effect is mainly attributed to the repression of PI3K‐Akt/MAPK signaling pathways at the molecular level. This powerful and surprising in situ eP‐regulated biomodulation demonstrates the advantages of convenient fabrication, inert immunogenicity, and biocompatibility, providing an alternative strategy for biomedical imaging and therapy.
Improved Black Phosphorus Nanocomposite Hydrogel for Bone Defect Repairing: Mechanisms for Advancing Osteogenesis
Authors: Wu Ailin , Ma Gaoqiang , Chen Yanhua , Gui Houda , Sun Baiyu , Zhang Bing , Liu Yingxue , Zhang Sen , Lian Guixue , Song Dawei , Zhang Dongjiao
Published: January 2025

Bone defects caused by fractures and diseases often do not heal spontaneously. They require external agents for repair and regeneration. Bone tissue engineering is emerging as a promising alternative to traditional therapies like autografts and allografts. Nanobiomaterials enhance osteoblast resistance to harsh environments by promoting cell differentiation. Black phosphorus (BP), a novel 2D material in biomedicine, displays unique osteogenic and antimicrobial properties. However, BP nanosheets still face clinical limitations like rapid degradation and high‐dose cytotoxicity. To address these, the introduction of amino‐silicon phthalocyanine (SiPc‐NH2) is investigated to see if it can enhance BP dispersion, reduce BP oxidation, and improve stability and safety for better osteogenesis and antibacterial effects through noncovalent interactions (van der Waals, π–π stacking and electrostatic interactions). Here, the self‐healing hydrogel is successfully designed using a step‐by‐step co‐assembly of BP and SiPc‐NH2. SiPc‐NH2 as a “structural stabilizer” of BP nanosheets reconstructed well‐dispersed BP‐SiPc‐NH2 nanosheets, which improves the biocompatibility of BP, reduces oxidation and enhances photothermal conversion, guaranteeing osteogenic and antimicrobial properties. Furthermore, findings show BP‐SiPc‐NH2‐induced mitochondrial changes support osteogenesis by regulating the crosstalk between Hippo and Wnt signaling pathways‐mediated mitochondrial homeostasis, and boosting cellular bioenergetics. Overall, this mitochondrial morphology‐based BP‐SiPc‐NH2 strategy holds great promise for bone repair applications.
2D Nanochannel Interlayer Realizing High‐Performance Lithium–Sulfur Batteries
Authors: Luo Zhi‐Hong , Zheng Min , Zhou Ming‐Xia , Sheng Xi‐Tong , Chen Xiao‐Li , Shao Jiao‐Jing , Wang Tian‐Shuai , Zhou Guangmin
Published: January 2025

Commercialization of lithium–sulfur (Li–S) batteries is largely limited by polysulfide shuttling and sluggish kinetics. Herein, 2D nanochannel interlayer composed of alternatively‐stacked porous silica nanosheets (PSN) and Ti3C2Tx‐MXene are developed. The 2D nanochannels with selective cation transport characteristics facilitate lithium ion rapid transport, while reject the translocation of polysulfide anions across the separator. The hydroxylated MXene shifts the p‐band center of the surface O on PSN closer to the Fermi level, leading to strong absorptive/catalytic effect for polysulfides and thus fast polysulfide transformation kinetics. Together with the ion/electron bi‐conduction function of PSN/MXene, the Li–S batteries deliver high initial capacity of 1443 mAh g−1 at 0.1 C, low‐capacity decay rate of 0.049% per cycle over 800 cycles at 2 C, and excellent rate capability. At a high sulfur loading of 5.2 mg cm−2, the cells present higher areal specific capacity than commercial lithium ion batteries. The pouch cells with lean electrolyte (E/S = 3.9 µL mg−1) yield a capacity of 2‐Ah at 100 mA, high energy density and excellent cycling stability. This contribution opens up new avenues for expanding application of 2D nanofluidics in electrochemical energy storage and conversion.