bluuebunny/crossref_metadata_2025 huggingface dataset:
Application of a Lagrangian transport model to organo-mineral aggregates within the Nazaré canyon
Authors: Pando S. , Juliano M. , Garcia R. , de Jesus Mendes P. A. , Thomsen L.
Published: January 2013

Abstract. In this study, a hydrodynamic model was applied to the Nazaré submarine canyon with boundary forcing provided by an operational forecast model for the West Iberian coast. After validation, a Lagrangian transport model was coupled to the hydrodynamic model to study the transport patterns of the organo-mineral aggregates along the Nazaré canyon comparing three different classes of organo-mineral aggregates. The results showed that the transport in the canyon is neither constant, nor unidirectional and that there are preferential areas where suspended matter is resuspended, transported and deposited. The results showed that the transport of the larger size classes of organo-mineral aggregates is less pronounced, and that there is a decrease in the phytodetrital carbon flux along the canyon. The Nazaré canyon acts as depocenter of sedimentary organic matter and the canyon is not a conduit of organo-mineral aggregates to the deep sea.
Influence of orbital forcing and solar activity on water isotopes in precipitation during the mid- and late Holocene
Authors: Dietrich S. , Werner M. , Spangehl T. , Lohmann G.
Published: January 2013

Abstract. In this study we investigate the impact of mid- and late Holocene orbital forcing and solar activity on variations of the oxygen isotopic composition in precipitation. The investigation is motivated by a recently published speleothem δ18O record from the well-monitored Bunker Cave in Germany. The record reveals some high variability on multi-centennial to millennial scales that does not linearly correspond to orbital forcing. Our model study is based on a set of novel climate simulations performed with the atmosphere general circulation model ECHAM5-wiso enhanced by explicit water isotope diagnostics. From the performed model experiments, we derive the following major results: (1) the response of both orbital and solar forcing lead to changes in surface temperatures and δ18O in precipitation with similar magnitudes during the mid- and late Holocene. (2) Past δ18O anomalies correspond to changing temperatures in the orbital driven simulations. This does not hold true if an additional solar forcing is added. (3) Two orbital driven mid-Holocene experiments, simulating the mean climate state approximately 5000 and 6000 yr ago, yield very similar results. However, if an identical additional solar activity-induced forcing is added, the simulated changes of surface temperatures as well as δ18O between both periods differ. We conclude from our simulation results that non-linear effects and feedbacks of the orbital and solar activity forcing substantially alter the δ18O in precipitation pattern and its relation to temperature change.
Porting marine ecosystem model spin-up using transport matrices to GPUs
Authors: Siewertsen E. , Piwonski J. , Slawig T.
Published: January 2013

Abstract. We have ported an implementation of the spin-up for marine ecosystem models based on transport matrices to graphics processing units (GPUs). The original implementation was designed for distributed-memory architectures and uses the Portable, Extensible Toolkit for Scientific Computation (PETSc) library that is based on the Message Passing Interface (MPI) standard. The spin-up computes a steady seasonal cycle of ecosystem tracers with climatological ocean circulation data as forcing. Since the transport is linear with respect to the tracers, the resulting operator is represented by matrices. Each iteration of the spin-up involves two matrix-vector multiplications and the evaluation of the used biogeochemical model. The original code was written in C and Fortran. On the GPU, we use the Compute Unified Device Architecture (CUDA) standard, a customized version of PETSc and a commercial CUDA Fortran compiler. We describe the extensions to PETSc and the modifications of the original C and Fortran codes that had to be done. Here we make use of freely available libraries for the GPU. We analyze the computational effort of the main parts of the spin-up for two exemplar ecosystem models and compare the overall computational time to those necessary on different CPUs. The results show that a consumer GPU can compete with a significant number of cluster CPUs without further code optimization.
Legitimising neural network river forecasting models: a new data-driven mechanistic modelling framework
Authors: Mount N. J. , Dawson C. W. , Abrahart R. J.
Published: January 2013

Abstract. In this paper we address the difficult problem of gaining an internal, mechanistic understanding of a neural network river forecasting (NNRF) model. Neural network models in hydrology have long been criticised for their black-box character, which prohibits adequate understanding of their modelling mechanisms and has limited their broad acceptance by hydrologists. In response, we here present a new, data-driven mechanistic modelling (DDMM) framework that incorporates an evaluation of the legitimacy of a neural network's internal modelling mechanism as a core element in the model development process. The framework is exemplified for two NNRF modelling scenarios, and uses a novel adaptation of first order, partial derivate, relative sensitivity analysis methods as the means by which each model's mechanistic legitimacy is explored. The results demonstrate the limitations of standard, goodness-of-fit validation procedures applied by NNRF modellers, by highlighting how the internal mechanisms of complex models that produce the best fit scores can have much lower legitimacy than simpler counterparts whose scores are only slightly inferior. The study emphasises the urgent need for better mechanistic understanding of neural network-based hydrological models and the further development of methods for elucidating their mechanisms.
Novelty detection in time series of ULF magnetic and electric components obtained from DEMETER satellite experiments above Samoa (29 September 2009) earthquake region
Authors: Akhoondzadeh M.
Published: January 2013

Abstract. Using ULF (ultra low frequency) measurements of magnetometer and ICE (Instrument Champ Electrique) experiments on board the DEMETER satellite, possible irregularities in ULF magnetic and electric components have been surveyed in the vicinity of Samoa (29 September 2009) earthquake region. The data used in this paper cover the period from 1 August 2009 to 11 October 2009. The anomalous variations in magnetic components (Bx, By and Bz) were clearly observed on 1 and 3 days before the event. It is seen that the periodic patterns of the magnetic components obviously changed prior to the earthquake. These unusual variations have been also observed in the variations of polarization index obtained from the magnetic components during the whole period at ~10:30 and ~22:30 LT. It is concluded that the polarization exhibits an apparent increase on 1 and 3 days preceding the earthquake. These observed unusual disturbances in ULF magnetic components were acknowledged using the detected perturbations in ULF electric components (Ex, Ey and Ez) in the geomagnetic coordinate system. Finally, the results reported in this paper were compared with previous results for this Samoa earthquake. Hence, the detected anomalies resulting from the magnetometer and ICE ULF waveforms in quiet geomagnetic conditions could be regarded as seismo-ionospheric precursors.
Macular Detachment Associated with an Optic Pit: Optical Coherence Tomography Patterns and Surgical Outcomes
Authors: Skaat Alon , Moroz Iris , Moisseiev Joseph
Published: January 2013

Purpose

TO describe the different optical coherence tomography (OCT) patterns in macular detachment associated with an optic disc pit and their long-term evolution following vitrectomy.

Methods

The data of 5 patients (9–43 years of age) with unilateral macular detachment associated with an optic disc pit, who had at least 1 year of follow-up, were compiled. Pars plana vitrectomy combined with gas tamponade was performed as the primary procedure in all patients. The OCT scans, best-corrected visual acuity (BCVA), and anatomic outcomes were documented.

Results

Two main OCT patterns were identified: a multilayer schisis pattern and a serous detachment pattern. Patients with multilayer schisis pattern were older and demonstrated worse mean preoperative (20/160) and postoperative (20/50) BCVA compared to serous detachment pattern patients (20/30 and 20/20, respectively). An average of 2.3 procedures per patient was needed in the multilayer schisis pattern compared to just one procedure in the serous detachment pattern. In 3 patients, additional pneumatic retinopexy was performed with full resolution of the subretinal fluid achieved.

Conclusions

Two distinct OCT patterns were observed in eyes with macular detachments with an optic pit, with different clinical features and prognoses. Excellent final visual acuity was obtained in all eyes, including those that required several surgical procedures.
Potent P2Y12 receptor inhibitors in patients with acute coronary syndrome
Authors: Orban M. , Massberg S. , Sibbing D.
Published: January 2013

Blood platelets are highly activated in the setting of an acute coronary syndrome (ACS). This fact mandates the need for potent platelet inhibition in ACS patients and especially in patients undergoing a percutaneous coronary intervention (PCI). The 2nd generation thienopyridine clopidogrel has been the standard of treatment in the past. Due to its pharmacological properties including a delayed onset of action, a large response variability and an insufficient antiplatelet action in some patients (low responsiveness or high on-treatment platelet reactivity), there was a need to develop, to study and to introduce more potent agents with a fast, reliable and potent antiplatelet action. With the 3rd generation thienopyridine prasugrel and with ticagrelor two potent agents for antiplatelet treatment of ACS patients are available now. Both drugs have demonstrated their superiority compared to clopidogrel in terms of thrombotic risk reduction in large-scale randomized trials. However, for these agents and in line with the expectations towards a more potent anti platelet treatment regimen, a higher risk for bleeding was observed for prasugrel and ticagrelor. Further on, the new anti platelet agents have their own and characteristic contraindications and numerous issues to be considered in clinical practice.

This review aims to provide an overview on the state of the art P2Y12 receptor directed inhibition in ACS patients with a focus on patients undergoing a coronary stenting procedure.
An Acoustic Study on Voice Change after Tonsillectomy
Authors: Lee Hwan Ho , Kim Joo Yeon , No Yong Hyeon
Published: January 2013

Objectives Many people have been concerned about voice change after tonsillectomy. The purpose of this study is to analyze changes in the voice and to think about changes in the vocal tract after surgery by using CSL-MDVP. Methods Data of 27 patients who underwent tonsillectomy were prospectively evaluated. Acoustic analysis was performed before, after 1 week, after 1 month from the surgery. Nasometer was also conducted. Results In acoustic analysis, there were no significant changes in F0, jitter, shimmer, NHR, VTI, SPI. But vAM was statistically increased. Vowels and nasal consonants formant frequency analysis results in patients showed no statistically correlation in 1months after tonsillectomy. Although the statistically increased in the nasal consonants /하나/. Conclusions Although the temporary increase or decrease in the acoustic factor or formant in the vowels and nasal consonants after tonsillectomy, but most factors are make no difference. The voice change that come postoperatively could be considered as no concern, but surgeons need to aware of various facts, which can affect voice changes before the surgery.
Acute Severe Hyponatremia with Seizure Following Polyethylene Glycol-Based Bowel Preparation for Colonoscopy
Authors: Lee Myung Hee , Lee Byung Hee , Oh Sook Kyung , Seo Ji Young , Kim Hyun Ju , Seo Bo Jung
Published: January 2013

4 liters of polyethylene glycol (PEG) solution is commonly used to evacuate the colon before colonoscopy. This substance, however, is known to cause electrolyte abnormalities such as hyponatremia. Seizures caused by hyponatremia associated with bowel preparation have only rarely been reported. We report the case that a 75-year-old woman with no prior history of seizures was developed severe hyponatremia (112 mEq/L) with generalized tonic-clonic seizure and mental change after ingestion of 4L of PEG solution. Past medical history was notable for thiazide diuretics. Her symptoms are improved during intravenous administration of hypertonic saline for the correction of hyponatremia. Patients with impaired ability to excrete free water those with renal insufficiency, hypothyroidism, mineralocorticoid deficiency, liver cirrhosis, or heart failure as well as those taking drugs which including thiazide diuretics, NASIDs, and ACE inhibitors have risk of hyponatremia following bowel preparation for colonoscopy. We conclude that physicians should check patient's condition and electrolyte abnormalities before colonoscopy procedures.
A Case of Infective Endocarditis Occurred during Treatment for Infectious Spondylitis Accompanied by Peptostreptococcus Anaerobius Bacteremia
Authors: Lee Byung Hee , Lee Myung Hee , Oh Sook Kyung , Seo Ji Young , Jeong Joon Hoon , Lee Jae Woo
Published: January 2013

It is necessary to distinguish between pyogenic and tuberculous spondylitis of infectious spondylitis, if it is pyogenic spondylitis, antimicrobial therapy should be directed against an identified microorganism and clinical assessment should be done at 4 weeks. But if microorganism is a anaerobic bacteria, especially Peptostreptococcus anaerobius, combination antibiotic therapy should be considered bacause it may be a component of mixed infections as a passenger and have abilities to induce abscesses, other bacterial growth as a synergy effect. In addition, echocardiography may be necessary because pyogenic spondylitis is associated with infective endocarditis about 12%. We report a 64-year-old man who was treated for infectious spondylitis accompanied by Peptostreptococcus anaerobius bacteremia, but had to undergo heart surgery because an attack of infective endocarditis with systemic embolism during hospitalization.
Design and Society: Innovation Through Appropriation and Adaptation
Authors: Burry Mark
Published: January 2013

‘To strive for a culture framed on great design is itself a fundamental innovation imperative.’ Here, Guest‐Editor Mark Burry poses the difficult question of how innovation might be achieved at a wider cultural level. How can society effectively seek to demand great design with confidence and authority? Burry looks specifically at the role of the design commissioner and the challenge of creating an overarching design system, as exemplified by the figure of Frank Pick, who in the first half of the 20th century steered London Underground's design identity, developing its enduring, highly distinctive graphics and architecture.
The Vitality of Matter and the Instrumentalisation of Life
Authors: Catts Oron , Zurr Ionat
Published: January 2013

Artists and researchers Oron Catts and Ionat Zurr of SymbioticA, based at the School of Anatomy, Physiology and Human Biology at the University of Western Australia, are internationally renowned as pioneers in the field of biological arts, challenging audiences with their tissue engineering projects. Catts and Zurr discuss how synthetic biology has increasingly become ‘the new frontier for exploitation’ and why there is currently ‘a resurgence of the application of engineering logic in the fields of the life sciences’ in which life itself becomes a raw material.
Differentiation in Vital Practice: An Analysis Using RMIT University of Technology and Design Interfaces With Architects
Authors: van Schaik Leon
Published: January 2013

One of the most influential figures in architectural education and practice today, Leon van Schaik, Professor of Architecture (Chair of Innovation) at RMIT in Melbourne, has dedicated the last two decades of his career to the promotion of local and international architectural culture through design practice research and the commissioning of building. Here he describes how he has nurtured a research‐oriented approach through his engagement with a network of ‘vital’ practitioners worldwide who are interested in strong ideas and pushing the questioning of the status quo.
The Mothers of Invention
Authors: Daniell Tom
Published: January 2013

Japan‐based architect and academic Tom Daniell puts out a call to architects, beseeching them not to lose sight of their role as creative inventors. Rather than being diverted into despair by the present confluence of ecological, economic and political crises, architects should be providing much needed optimism, thinking beyond the current situation with utopian visions. He challenges the view that future innovation is to be located in collective collaborations, regarding ‘true innovators’ to be individuals, such as Rem Koolhaas, Hernan Diaz Alonso or Philippe Rahm, who provide the essential entrepreneurial catalyst for the interaction of other people and ideas.
Crystallization and fracture behaviors of high‐density polyethylene/linear low‐density polyethylene blends: The influence of short‐chain branching
Authors: Shen Guanghao , Shen Hongwang , Xie Banghu , Yang Wei , Yang Mingbo
Published: January 2013

Two commercial polyethylene samples, linear high‐density polyethylene (HDPE) and branched linear low‐density polyethylene with almost the same molecular weight distribution but different contents of short‐chain branching (SCB) were melt blended based on the consideration of practical application. Dynamic rheology analysis indicated good compatibility of all the blends with different compositions. Common differential scanning calorimeter (DSC) tests and successive self‐nucleation and annealing (SSA) treatment showed several interesting phenomena. First, without consideration of the effect of molecular weight and molecular weight distribution impact, co‐crystallization occurred at all ratios even the two components had a considerable difference in SCB distribution. Second, in SSA curves the area of the first two melting peaks, i.e., the amount of the thick lamellas of the two components showed an obvious positive deviation with the increase of HDPE content owing to the crystal perfection improved by the co‐crystallization. Essential Work of Fracture tests proved the co‐crystallization effects had a positive effect on the improvement of the resistance to crack propagation. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Influence of Isotope Substitution on Lattice and Spin‐Peierls‐Type Transition Features in One‐Dimensional Nickel Bis‐dithiolene Spin Systems
Authors: Yuan Guo‐Jun , Zhao Shun‐Ping , Wang Can , Liu Jian‐Lan , Ren Xiao‐Ming
Published: January 2013

Four new 1D spin‐Peierls‐type compounds, [D5]1‐(4′‐R‐benzyl)pyridinium bis(maleonitriledithiolato)nickelate ([D5]R‐Py; R=F, I, CH3, and NO2), were synthesized and characterized structurally and magnetically. These 1D compounds are isostructural with the corresponding non‐deuterated compounds, 1‐(4′‐R‐benzyl)pyridinium bis(maleonitriledithiolato)nickelate (R‐Py; R=F, I, CH3, and NO2). Compounds [D5]R‐Py and R‐Py (R=F, I, CH3, and NO2) crystallize in the monoclinic space group P21/c with uniform stacks of anions and cations in the high‐temperature phase and triclinic space group P$\bar 1$ with dimerized stacks of anions and cations in the low‐temperature phase. Similar to the non‐deuterated R‐Py compounds, a spin‐Peierls‐type transition occurs at a critical temperature for each [D5]R‐Py compound; the magnetic character of the 1D S=1/2 ferromagnetic chain for [D5]F‐Py and the 1D S=1/2 Heisenberg antiferromagnetic chain for others appear above the transition temperature. Spin‐gap magnetic behavior was observed for all of these compounds below the transition temperature. In comparison to the corresponding R‐Py compound, the cell volume is almost unchanged for [D5]F‐Py and shows slight expansion for [D5]R‐Py (R=I, CH3, and NO2) as well as an increase in the spin‐Peierls‐type transition temperature for all of these 1D compounds in the order of F>I≈CH3≈NO2. The large isotopic effect of nonmagnetic countercations on the spin‐Peierls‐type transition critical temperature, TC, can be attributed to the change in ω0 with isotope substitution.
Albumin is the main plasma binding protein for indoxyl sulfate and p‐cresyl sulfate
Authors: Viaene Liesbeth , Annaert Pieter , de Loor Henriette , Poesen Ruben , Evenepoel Pieter , Meijers Björn
Published: January 2013

Indoxyl sulfate and p‐cresyl sulfate are two uremic retention solutes implicated in the uremic syndrome. Removal during dialysis is limited, mainly due to protein binding. Binding characteristics to healthy albumin have recently been characterized. Whether uremia alters the binding characteristics of albumin is currently unknown. Moreover, protein binding values previously determined with ultrafiltration are in sharp contrast to recently reported values based on microcalorimetry. In the present study, indoxyl sulfate and p‐cresyl sulfate binding were therefore quantified using both equilibrium dialysis and ultrafiltration. Deming regression demonstrated good agreement between equilibrium dialysis and ultrafiltration. Free serum concentrations of indoxyl sulfate (+26.6%) and p‐cresyl sulfate (+19.7%) were slightly higher at body temperature compared with at room temperature. To investigate binding kinetics, the plasma of healthy individuals or hemodialysis patients was titrated with albumin solutions. Theoretical models of protein binding were fitted to observed titration curves. Binding coefficients of both toxins were highest in purified albumin, and were reduced from healthy to uremic plasma. In conclusion, the ultrafiltration–HPLC technique reliably measures free serum concentrations of indoxyl sulfate and p‐cresyl sulfate. Albumin is the main binding protein, both in health and in advanced stages of chronic kidney disease. Modeling suggests that albumin contains two binding sites for both toxins, a single high affinity binding site and a second low affinity binding site. The high affinity binding site accounts for at least 90% of overall binding. Competition for this binding site could be used to augment free solute concentrations during dialysis, thus improving epuration. Copyright © 2013 John Wiley & Sons, Ltd.
Rapid determination of isoamyl nitrite in pharmaceutical preparations by flow injection analysis with on‐line UV irradiation and luminol chemiluminescence detection
Authors: Kishikawa Naoya , Kondo Naoko , Amponsaa‐Karikari Abena , Kodamatani Hitoshi , Ohyama Kaname , Nakashima Kenichiro , Yamazaki Shigeo , Kuroda Naotaka
Published: January 2013

Isoamyl nitrite is used as a therapeutic reagent for cardiac angina and as an antidote for cyanide poisoning, but it is abused because of its euphoric properties. Therefore, a method to determine isoamyl nitrite is required in many fields, including pharmaceutical and forensic studies. In this study, a simple, rapid and sensitive method for the determination of isoamyl nitrite was developed using a flow injection analysis system equipped with a chemiluminescence detector and on‐line photoreactor. This method is based on on‐line ultraviolet irradiation of isoamyl nitrite and subsequent luminol chemiluminescence detection without the addition of an oxidant. A linear standard curve was obtained up to 1.0 μM of isoamyl nitrite with a detection limit (blank + 3SD) of 0.03 μM. The method was successfully applied to determine isoamyl nitrite content in pharmaceutical preparations. Copyright © 2013 John Wiley & Sons, Ltd.
Split decision
Authors: Neumann U P , Dejong C H C
Published: January 2013

An exciting development
FOXP3 genetic variant and risk of acute coronary syndrome in Chinese Han population
Authors: Yang Qing , Chen Yu , Yong Wei
Published: January 2013

Coronary artery disease is the most common type of heart disease and a leading cause of morbidity and mortality all over the world. Acute coronary syndrome (ACS) is the most serious form of coronary artery disease. Recently, many studies indicated that genetic susceptibility may play a vital role in the pathogenesis of coronary heart disease including ACS. Forkhead/winged helix transcription factor (FOXP3) gene polymorphisms have been previously found to be associated with inflammatory diseases. To determine whether FOXP3 polymorphisms are associated with ACS, we examined the single nucleotide polymorphism rs3761548 of FOXP3 gene by polymerase chain reaction—polyacrylamide gel electrophoresis in 226 ACS patients and 259 unrelated healthy subjects. Our results showed that single nucleotide polymorphism rs3761548 had association with ACS in Chinese Han population. These data indicate that, for the first time, FOXP3 gene polymorphism may appear to play an important role in the susceptibility of ACS in Chinese Han population. Copyright © 2013 John Wiley & Sons, Ltd.
The Marine Polyketide Myriaporone 3/4 Stalls Translation by Targeting the Elongation Phase
Authors: Muthukumar Yazh , Roy Myriam , Raja Aruna , Taylor Richard E. , Sasse Florenz
Published: January 2013

Myriaporone 3/4, a cytotoxic polyketide, has been reported as an inhibitor of eukaryotic protein synthesis. However, the mechanism by which it inhibits translation was unknown. Here we show that myriaporone 3/4 stalls protein synthesis in the elongation phase by inducing phosphorylation of eukaryotic elongation factor 2. The phosphorylation results from direct binding of myriaporone 3/4 to eukaryotic elongation factor 2 kinase. Our study also shows that myriaporone 3/4 in the nanomolar range inhibits in vitro tube formation by endothelial cells without being cytotoxic. In general, myriaporone 3/4 was at least 300 times less toxic to primary cells than to tumor cells.
Organometallic Catalysts for Use in a Fuel Cell
Authors: Matsumoto Takahiro , Kim Kyoungmok , Nakai Hidetaka , Hibino Takashi , Ogo Seiji
Published: January 2013

We report the successful increase in performance of a fuel cell based on organometallic catalysis. An organometallic [NiIIRuIV] peroxo complex functions as cathode catalyst and was designed following mechanistic consideration of the cell. It was confirmed that the organometallic [NiIIRuIV] peroxo catalyst could function in the fuel cell with a 240 % increase in power output over our previous systems. This organometallic catalyst can act in both solid and solution phases and allows observation of the mechanism, hence providing us further opportunity for future improvement.
From Regioselective Condensation to Regioselective N‐Alkylation: A Novel and Environmentally Benign Strategy for the Synthesis of N,N′‐Alkyl Aryl Ureas and N,N′‐Dialkyl Ureas
Authors: Li Feng , Sun Chunlou , Shan Haixia , Zou Xiaoyuan , Xie Jianjiang
Published: January 2013

A protocol for the synthesis of N,N′‐alkyl aryl ureas and N,N′‐dialkyl ureas by transition metal‐catalyzed regioselective N3‐alkylation of the N‐monosubstituted ureas with alcohols was proposed and accomplished. In the presence of an iridium/base system, the desired N,N′‐alkyl aryl ureas and N,N′‐dialkyl ureas were obtained with 70–93 % yields, and no isomeric N1‐alkylated and N3‐dialkylated products were formed in all cases. From both synthetic and environmental point of views, the reaction is highly attractive because of easily available starting materials, high atom efficiency and the formation of water as the only side product. Apparently, the research opens up the design of regioselective N‐alkylation of amines with alcohols based on the regioselective condensation of amines with aldehydes, facilitating the progress of the “hydrogen autotransfer” (or “hydrogen‐borrowing”) process.
Hydrothermal Treatment of Carboxy‐methyl Cellulose Salt: Formation and Decomposition of Furans, Pentenes and Benzenes
Authors: Kröger M. , Hartmann F. , Klemm M.
Published: January 2013

Carboxymethyl cellulose salt as a model compound was treated hydrothermally to understand the degradation and formation of several chemicals (furfural, 5‐(hydroxymethyl)‐furancarboxaldehyde, and benzene derivatives) that might be interesting as platform chemicals or fuels. To realize a manageable control, closed quartz capillaries were chosen as reactor. Experiments were conducted at temperatures from 250 (subcritical water) to 450 °C (supercritical water) and reaction times from 1 to 60 min. By studying the gas chromatography‐mass spectrometry analysis results of the liquid products, their formation and degradation were detected. It was observed that certain substances only appear for several minutes and are then degraded, while for others the concentration increases at lower rate and keeps stable even for long reaction times. The formation of several benzoic structures from a non‐ring‐structured precursor showed that different reaction mechanisms are involved. Different reaction temperatures showed good correlation to the formation rate of several substances.
ChemInform Abstract: Pressure‐Induced Crystal Structure and Spin‐State Transitions in Magnetite (Fe3O4).
Authors: Ju Sheng , Cai Tian‐Yi , Lu Hai‐Shuang , Gong Chang‐De
Published: January 2013

Pressure‐induced phase transitions in Fe3O4 are characterized by first‐principles DFT calculations.
ChemInform Abstract: Theoretical Prediction of the Fundamental Properties for the Ternary Li2PtH6 and Na2PtH6
Authors: Ghebouli M. A. , Choutri H. , Bouarissa N. , Ghebouli B. , Bouhemadou A. , Soyalp F. , Ucgun E. , Ocak H. Y.
Published: January 2013

DFT based prediction of elastic moduli, energy gaps, and optical parameters of the indirect gap semiconductors of title
ChemInform Abstract: Dumbbells of Five‐Connnected Silicon Atoms and Superconductivity in the Binary Silicides MSi3 (M: Ca, Y, Lu).
Authors: Schwarz Ulrich , et al. et al.
Published: January 2013

The new metastable title compounds are prepared by high pressure/high temperature reaction of the elements (Ta ampules, 12—15 GPa, 900—1400 K).
ChemInform Abstract: Chemical Manipulation of Magnetic Ordering in Mn1‐xSnxBi2Se4 Solid‐Solution.
Authors: Ranmohotti Kulugammana G. S. , Djieutedjeu Honore , Poudeu Pierre F. P.
Published: January 2013

Title solid solutions with x = 0, 0.3, and 0.75 are synthesized from the elements (723—1000 K, 6—7 d) and characterized by single crystal XRD, XPS, and magnetic susceptibility measurements.
ChemInform Abstract: Lanthanoid Single‐Ion Magnets Based on Polyoxometalates with a 5‐Fold Symmetry: The Series [LnP5W30O110]12‐ (Ln3+: Tb, Dy, Ho, Er, Tm, and Yb).
Authors: Cardona‐Serra S. , Clemente‐Juan J. M. , Coronado E. , Gaita‐Arino A. , Camon A. , Evangelisti M. , Luis F. , Martinez‐Perez M. J. , Sese J.
Published: January 2013

The compounds K12LnP5W30O110 ·nH2O (Ln3+: Tb, Dy, Ho, Er, Tm, and Yb) are prepared from aqueous solutions of K12.5Na1.5 [NaP5W30O110] and LnCl3 (autoclave, 160 °C, 24 h) and characterized by static and dynamic magnetic measurements.
ChemInform Abstract: Super‐Long Barnesite Na2V6O16·3H2O Nanobelts for Aligned Film Electrodes with Enhanced Anisotropic Electrical Transport.
Authors: Xue Yan , Wu Jian , Zhang Hanyang , Luo Yi , Zhang Xiaodong , Du Zuliang , Xie Yi
Published: January 2013

Na2V6O16·3H2O nanobelts with lengths of 100—200 μm are hydrothermally synthesized from aqueous solutions of Na3VO4 and HCl (autoclave, 200 °C, 24 h, 99% yield).
ChemInform Abstract: Electrochemical Performance of NASICON Type Carbon‐Coated LiTi2(PO4)3 with a Spinel LiMn2O4 Cathode.
Authors: Aravindan V. , Chuiling W. , Madhavi S.
Published: January 2013

NASICON‐type LiTi2(PO4)3 particles are synthesized by a modified Pechini‐type polymerizable complex method at 1000 °C in air (24 h).
ChemInform Abstract: High‐Capacity Micrometer‐Sized Li2S Particles as Cathode Materials for Advanced Rechargeable Lithium‐Ion Batteries.
Authors: Yang Yuan , Zheng Guangyuan , Misra Sumohan , Nelson Johanna , Toney Michael F. , Cui Yi
Published: January 2013

The electrochemical study of Li2S as cathode material shows that a large potential barrier (1 V) exists at the beginning of the charge process.
ChemInform Abstract: Chemical Intercalation of Zerovalent Metals into 2D Layered Bi2Se3 Nanoribbons.
Authors: Koski Kristie J. , Wessells Colin D. , Reed Bryan W. , Cha Judy J. , Kong Desheng , Cui Yi
Published: January 2013

Zerovalent metal atoms (such as Cu, Ag, Sn, Au, In, Co, Fe, Ni) are intercalated into two‐dimensional layered Bi2Se3 nanoribbons using disproportionation redox reactions or carbonyl decomposition to generate dilute zerovalent metal atoms in a refluxing solution.
ChemInform Abstract: Large‐Scale and Facile Preparation of Pure Ammonia Borane Through Displacement Reactions.
Authors: Chen Xuenian , Bao Xiaoguang , Billet Beau , Shore Sheldon G. , Zhao Ji‐Cheng
Published: January 2013

Pure NH3BH3 is prepared at the 100 g scale by displacement reactions of either NH3 and Me2S·BH3 with 94% yield, or NH3 and Ph‐NMe2·BH3 with 91% yield, with both reactions performed in toluene at room temperature.
ChemInform Abstract: A New “Fully Reduced” Polyoxovanadate Constructed from Nanosized Triangle‐Shaped [VIII3VIV18P6 O60(DACH)3]9‐ Cluster Anions Exhibiting Ferrimagnetic Interactions.
Authors: Wang Cong‐Ling , Zhang Zhi‐bin , Fu Jie , Xu Yan , Zhu Dun‐ru
Published: January 2013

The new compound NH4{ [Zn4(DACH)7(H2O)3] [VIII3VIV18P6 O60(DACH)3]}·19H2O (DACH: 1,2‐diaminocyclohexane) is synthesized by hydrothermal reaction of NH4VO3, Zn(OAc)2, DACH, H3PO4, and H2O (autoclave, 160 °C, 6 d).
ChemInform Abstract: Self‐Assembly and Photocatalytic Properties of Polyoxoniobates: {Nb24O72}, {Nb32O96}, and {K12Nb96O288} Clusters.
Authors: Huang Peng , Qin Chao , Su Zhong‐Min , Xing Yan , Wang Xin‐Long , Shao Kui‐Zhan , Lan Ya‐Qian , Wang En‐Bo
Published: January 2013

The new compounds (III), (IV), and (V) with molecular triangle, molecular square, and cuboctahedral molecular cage geometries, respectively, are characterized by single crystal XRD and electrospray ionization mass spectrometry.
ChemInform Abstract: Two‐Dimensional Antiferromagnetism in the [Mn3+xO7][Bi4O4.5‐y] Compound with a Maple‐Leaf Lattice.
Authors: Aliev Almaz , Huve Marielle , Colis Silviu , Colmont Marie , Dinia Aziz , Mentre Olivier
Published: January 2013

Black single crystals of Bi4Mn3O11.5 are obtained besides Bi6O8Cl from the solid state reaction of Bi2O3, BiOCl, PbO, and MnO2 (sealed Au tube, 1173 K, 12 h).
ChemInform Abstract: Crystalline Iron Oxohalide Nanotube Pea Pods.
Authors: Zimmermann Iwan , Johnsson Mats , Lidin Sven
Published: January 2013

Single crystals of Fe7Sb3 (PO4)3O6Cl3 and Fe7Sb3 (PO4)3O6Br3 are prepared from 2:1:1:1:1:1 mixtures of Sb2O3, Fe2O3, FeO, FeCl3, FeCl2, and (NH4)H2PO4, and 3:1:6:1:6:6 mixtures of Sb2O3, Fe2O3, FeO, FeBr3, FeBr2, and (NH4)H2PO4, respectively (silica tubes, 500 °C, 70 h).
ChemInform Abstract: Iron‐Catalyzed Cross‐Coupling of Halohydrins with Aryl Aluminum Reagents: A Protecting‐Group‐Free Strategy Attaining Remarkable Rate Enhancement and Diastereoinduction.
Authors: Kawamura Shintaro , Kawabata Tatsuya , Ishizuka Kentaro , Nakamura Masaharu
Published: January 2013

The cross‐coupling reaction of protected trans‐4‐chlorocyclohexanol derivatives with in situ formed aryl aluminum reagents proceeds with low diastereoselectivity whilst analogous reactions of unprotected trans‐4‐chlorocyclohexanol demonstrate a good trans‐selectivity.
ChemInform Abstract: Convergent Diastereoselective Preparation of Adjacent Quaternary Stereocenters in an Acyclic System.
Authors: Mejuch Tom , Dutta Bishnu , Botoshansky Mark , Marek Ilan
Published: January 2013

A sequential carbometalation—zinc homologation—allylation reaction of propargyl or ethynyl ethers with in situ generated alkyl—copper reagents and aromatic ketones provides access to vicinal diol derivatives containing two adjacent quaternary stereocenters (V) and (IX).
ChemInform Abstract: One‐Step Method for the Synthesis of Nitroisoindoles via 1,3‐Dipolar Cycloaddition of Azomethine Ylides to Polynitrobenzenes.
Authors: Starosotnikov Alexey M. , Bastrakow Maxim A. , Kachala Vadim V. , Belyakov Pavel A. , Fedyanin Ivan V. , Shevelev Svyatoslav
Published: January 2013

Annulation of a pyrrole ring to polynitrobenzenes provides a pathway to previously unknown functionalized nitroisoindoles, based on 1,3‐dipolar cycloaddition of in situ generated azomethine ylides to polynitroarenes.
ChemInform Abstract: Chirality Transfers Through Sequential Sigmatropic Rearrangements of Allylic Vicinal Diols: Development and Application to Total Synthesis of (‐)‐Kainic Acid.
Authors: Kitamoto Katsunori , Nakayama Yasuaki , Sampei Mana , Ichiki Masato , Furuya Naoya , Sato Takaaki , Chida Noritaka
Published: January 2013

Starting from enantiopure allylic vicinal diols, Claisen/Claisen rearrangements install two identical functional groups while sequential Claisen/Overman rearrangements install two different functional groups.
ChemInform Abstract: Homogeneous Asymmetric Transfer Hydrogenation of Ketones Using a Ruthenium Catalyst Anchored on Chitosan: Natural Chirality at Work.
Authors: Babin Mathieu , Clement Roxanne , Gagnon Jonathan , Fontaine Frederic‐Georges
Published: January 2013

The asymmetric transfer hydrogenation of aromatic and aliphatic ketones is smoothly achieved using a RuCl2(p‐cymene) catalyst immobilized on pivaloyl‐functionalized chitosan as only source of chirality.
ChemInform Abstract: Fast Pd‐ and Pd/Cu‐Catalyzed Direct C—H Arylation of Cyclic Nitrones. Application to the Synthesis of Enantiopure Quaternary α‐Amino Esters.
Authors: Demory Emilien , Farran Daniel , Baptiste Benoit , Chavant Pierre Y. , Blandin Veronique
Published: January 2013

Cyclic nitrones undergo fast, clean, and efficient coupling with a wide range of aromatic halides.
ChemInform Abstract: Titanium(IV) Isopropoxide as an Efficient Catalyst for Direct Amidation of Nonactivated Carboxylic Acids.
Authors: Lundberg Helena , Tinnis Fredrik , Adolfsson Hans
Published: January 2013

A broad spectrum of carboxylic acids and amines (primary and secondary ones) can be used for the successful preparation of amides.
ChemInform Abstract: Stereodivergent Zinc‐Mediated Three‐Component Synthesis of Tri‐ and Tetrasubstituted Alkenes.
Authors: Miersch Anne , Hilt Gerhard
Published: January 2013

The addition of benzyl bromide (II) to alkynes proceeds in a stereoselective manner, depending on the amount of zinc.
ChemInform Abstract: BF3·OEt2/TMSN3‐Mediated Regioselective Azidolysis of Vinylaziridines.
Authors: Righi Giuliana , Bovicelli Paolo , Marucci Cristina , Tirotta Ilaria
Published: January 2013

A recently reported study on the azidolysis of vinyl epoxides is extended to analogous N‐protected aziridines (I) to produce azides (II), accompanied by low amounts of azides (III).
ChemInform Abstract: Quick Installation of a 1,4‐Difunctionality via Regioselective Nickel‐Catalyzed Reductive Coupling of Ynoates and Aldehydes.
Authors: Rodrigo Sanjeewa K. , Guan Hairong
Published: January 2013

Slow addition of some propiolates to aldehydes and Et3SiH in the presence of Ni‐catalyst is found to allow an efficient and selective access to silylated γ‐hydroxy‐α,β‐enoates.
ChemInform Abstract: Ph3P/I2‐Catalyzed Beckmann Rearrangement of Ketoximes into Amides.
Authors: Xu Feng , Wang Ni‐Ge , Tian You‐Ping , Chen Yong‐Mei , Liu Wei‐Chun
Published: January 2013

Ph3P/I2 is a convenient catalyst system for the Beckmann rearrangement of ketoximes into corresponding amides.
ChemInform Abstract: Copper‐Catalyzed Reductive Amination of Aromatic and Aliphatic Ketones with Anilines Using Environmental‐Friendly Molecular Hydrogen.
Authors: Werkmeister Svenja , Junge Kathrin , Beller Matthias
Published: January 2013

Acetophenone (I) reacts with different anilines (II) to the desired amines (III) in good yields.
ChemInform Abstract: A Practical Procedure of Propargylation of Aldehydes.
Authors: Ghosh Papiya , Chattopadhyay Angshuman
Published: January 2013

Low‐valent iron‐ or tin‐mediated reactions of excess propargyl bromide with aldehydes afford homopropargyl alcohols as main or sole products.
ChemInform Abstract: Pd(OAc)2‐Catalyzed Alkoxylation of Arylnitriles via sp2 C—H Bond Activation Using Cyano as the Directing Group.
Authors: Li Wu , Sun Peipei
Published: January 2013

In the presence of Na2S2O8 and Pd(O‐Ac)2, aromatic nitriles react with primary alcohols to afford ortho‐alkoxylated products in moderate to good yields.
ChemInform Abstract: Selective Conversion of Aldehydes into Nitriles and Primary Amides in Aqueous Media.
Authors: Wang Liang , Shen Chen , Wang Hai‐ping , Zhou Wei‐you , Sun Fu‐an , He Ming‐Yang , Chen Qun
Published: January 2013

An efficient and selective conversion of various aldehydes into corresponding nitriles and primary amides using tBuOOH and aqueous ammonia is presented.
ChemInform Abstract: Aerobic Oxidative Esterification of Benzyl Alcohols with Catalytic Tetrabromomethane under Visible Light Irradiation.
Authors: Nobuta Tomoya , Fujiy Akitoshi , Hirashima Shin‐ichi , Tada Norihiro , Miura Tsuyoshi , Itoh Akichika
Published: January 2013

A new photooxidative method allows the synthesis of aromatic alkyl esters under metal‐free conditions.
ChemInform Abstract: Improvement in the Synthesis of (Z)‐Organylthioenynes via Hydrothiolation of Buta‐1,3‐diynes: A Comparative Study Using NaOH or TBAOH as Base.
Authors: Baroni Adriano C. M. , et al. et al.
Published: January 2013

Generally, the reactions using Bu4NOH are more rapid and efficient.
ChemInform Abstract: Bi2O3‐Catalyzed Asymmetric Oxidation of Sulfides.
Authors: Malik Payal , Chakraborty Debashis
Published: January 2013

The combination is very efficient to give sulfoxides with high enantioselectivities.
ChemInform Abstract: Unsymmetrical Tetrasubstituted Ureas from Tertiary Carbamoylimidazole: Activation by AlMe3.
Authors: Velavan A. , Sumathi S. , Balasubramanian K. K.
Published: January 2013

A general and efficient access towards unsymmetrical urea derivatives is presented, involving the amination of carbamoylimidazoles in the presence of AlMe3.
ChemInform Abstract: Synthesis of 1,2‐Disubstituted Acetylenes via Copper‐Catalyzed Suzuki Coupling of Organoboronic Acids with 1,1‐Dibromo‐1‐alkenes.
Authors: Liu Jidan , Dai Fenglin , Yang Zhiyong , Wang Sizhuo , Xie Kai , Wang Anwei , Chen Xiang , Tan Ze
Published: January 2013

Various 1,2‐diarylacetylenes can be prepared under optimized conditions.
ChemInform Abstract: Chiral Broensted Acid‐Catalyzed Diastereo‐ and Enantioselective Synthesis of CF3‐Substituted Aziridines.
Authors: Chai Zhuo , Bouillon Jean‐Philippe , Cahard Dominique
Published: January 2013

If α‐imino glyoxalate or α‐imino glyoxylic amide are used as starting material the corresponding cis‐triazoline is also formed.
ChemInform Abstract: Efficient Synthesis of the Odorant, 2‐Nonen‐4‐olide.
Authors: Dai Yi‐feng , Tian Hong‐yu , Sun Bao‐guo , Sun Yu‐mei , Chen Hai‐tao , Liu Xiao‐yu
Published: January 2013

An efficient three‐step synthesis of nonenolide (V), a lactose with coconut‐like and rancid odour, is given.
ChemInform Abstract: Approach to Construct Polysubstituted 1,2‐Dihydronaphtho[2,1‐b]furans and Their Aerobic Oxidative Aromatization.
Authors: Huo Congde , Xu Xiaolan , An Jinzhu , Jia Xiaodong , Wang Xicun , Wang Cheng
Published: January 2013

Triarylaminium‐mediated treatment of 2‐naphthols with chalcone epoxides is found to results in convenient formation of dihydronaphthofurans.
ChemInform Abstract: Triple Channel Responsive Cu2+ Probe.
Authors: Algi Melek Pamuk , Oeztas Zahide , Algi Fatih
Published: January 2013

Compound (I) induces triple channel (colorimetric, fluorogenic and voltammetric) responses to Cu(II) ions.
ChemInform Abstract: Highly Enantioselective Friedel—Crafts Alkylation of Indoles and Pyrrole with β,γ‐Unsaturated α‐Ketoesters Catalyzed by Heteroarylidene‐Tethered Bis(oxazoline) Copper Complexes.
Authors: Liu Lei , Ma Hongli , Xiao Yumei , Du Fengpei , Qin Zhaohai , Li Nan , Fu Bin
Published: January 2013

This work presents the first examples of asymmetric Friedel‐Crafts alkylation of unprotected pyrrole with β, γ‐unsaturated α‐ketoesters in good yields with high enantioselectivity.
ChemInform Abstract: Isocyanide‐Based Multicomponent [2 + 2 + 1]‐Cycloaddition Strategy to Construct Functionalized Spirocyclic Oxindoles.
Authors: Jie Haohua , Li Jian , Li Chunju , Jia Xueshun
Published: January 2013

With malononitriles (I) or (V) spirocyclic oxindoles of type (IV)/(VIII) are produced.
ChemInform Abstract: Copper‐Catalyzed Domino Coupling Reaction: An Efficient Method to Synthesize Oxindoles.
Authors: Hsieh Jen‐Chieh , Cheng An‐Yi , Fu Jun‐Hao , Kang Ting‐Wei
Published: January 2013

Intramolecular Cu‐catalyzed cyclization of o‐bromoarylacetonitrile derivatives provides a novel efficient access towards a wide variety of oxindole derivatives.
ChemInform Abstract: Iodine(III)‐Mediated Bicyclic Diazenium Salt Formation.
Authors: Al‐Bataineh Nezar Q. , Brewer Matthias
Published: January 2013

Treatment of arylhydrazones (I) with Ph‐I(O‐Tf)2, generated in situ, results in formation of bicyclic diazenium salts.
ChemInform Abstract: Indium Trifluoride: A Highly Efficient Catalyst for the Synthesis of Fluorine‐Containing 2,4,5‐Trisubstituted Imidazoles under Solvent‐Free Conditions.
Authors: Reddy Mudumala Veeranarayana , Jeong Yeon Tae
Published: January 2013

A novel and improved method for the synthesis of fluorine containing trisubstituted imidazoles (III) (16 examples) using an InF3‐catalyzed one‐pot, three‐component reaction is developed.
ChemInform Abstract: Tailor‐Made Synthesis of Various Backbone‐Substituted Imidazolinium Salts by Triflic Anhydride Mediated Intramolecular Cyclization.
Authors: Zhang Jun , Su Xiaolong , Fu Jun , Qin Xinke , Zhao Meixin , Shi Min
Published: January 2013

In the course of the investigations stereoselective formation of the syn‐isomer (X) and regioselective alkylation of amidine (XI) at the sterically less hindered N‐substituent is observed.
ChemInform Abstract: Synthesis, Structural and Biological Characterization of 5‐Phenylhydantoin Derivatives as Potential Anticonvulsant Agents.
Authors: Trisovic Nemanja , Timic Tamara , Divljakovic Jovana , Rogan Jelena , Poleti Dejan , Savic Miroslav M. , Uscumlic Gordana
Published: January 2013

Title compounds of type (VI) are prepared and tested as potential anticonvulsant agents.
ChemInform Abstract: KF/Al2O3: Solid‐Supported Reagent Used in 1,3‐Dipolar Cycloaddition Reaction of Nitrile Oxide.
Authors: Boruah Monalisa , Konwar Dilip
Published: January 2013

An efficient one‐pot synthesis of 2‐isoxazolines via cycloaddition of nitrile oxides with olefins using solid‐supported KF as base is presented.
ChemInform Abstract: Facile Synthesis of Novel Fluorine Containing Pyrazole Based Thiazole Derivatives and Evaluation of Antimicrobial Activity.
Authors: Desai N. C. , Joshi V. V. , Rajpara K. M. , Vaghani H. V. , Satodiya H. M.
Published: January 2013

The synthesized compounds (V) show potent inhibitory action against Gram‐positive and Gram‐negative bacteria and against different strains of fungi.
ChemInform Abstract: Aqueous Microwave‐Assisted One‐Pot Synthesis of N‐Substituted Rhodanines.
Authors: Nitsche Christoph , Klein Christian D.
Published: January 2013

Two different approaches under microwave irradiation are presented.
ChemInform Abstract: 4,4′‐Bithiazole‐Based Tetraarylenes: New Photochromes with Unique Photoreactive Patterns.
Authors: Gavrel Gildas , Yu Pei , Leaustic Anne , Guillot Regis , Metivier Remi , Nakatani Keitaro
Published: January 2013

Title compounds (I) bearing an 1,3,5,7‐octatetraene photoreactive backbone are synthesized and their photochromic behavior is investigated.
ChemInform Abstract: An “On‐Water” Exploration of CuO Nanoparticle Catalyzed Synthesis of 2‐Aminobenzothiazoles.
Authors: Rout Saroj Kumar , Guin Srimanta , Nath Jayashree , Patel Bhisma K.
Published: January 2013

Ortho‐fluoro and ‐chloro substrates (I) undergo intramolecular arylthiolation via in situ generated halothioureas in the presence of CuO nanoparticles.