bluuebunny/crossref_metadata_2025 huggingface dataset:
ICMR-MDRF Diabetes Biosamples: Cohort profile
Authors: Anjana Ranjit Mohan , Deepa Mohan , Pradeepa Rajendra , Amutha Anandakumar , Sridevi Kothandapani , Sathishraj Sekar , Menaka Sadasivam , Vijayabaskar Santhappan , Elangovan Nirmal , Parthiban Kumar , Dhanasekaran Lakshamanan , Hemavathy Saite , Tandon Nikhil , Kaur Tanvir , Dhaliwal Rupinder Singh , Unnikrishnan Ranjit , Mohan Viswanathan ,   for the ICMR–INDIAB Collaborative Study Group
Published: December 2024

Background & objectives

Biobanks are crucial for biomedical research, enabling new treatments and medical advancements. The biobank at the Madras Diabetes Research Foundation (MDRF) aims to gather, process, store, and distribute biospecimens to assist scientific studies.

Methods

This article details the profile of two cohorts: the Indian Council of Medical Research–India Diabetes (ICMR–INDIAB) study and the Registry of people with diabetes in India with young age at onset (ICMR–YDR). The ICMR–INDIAB study is the largest epidemiological study on diabetes in India, encompassing a nationally representative sample of individuals aged 20 yr and older from urban and rural areas in every State across the country. The ICMR–YDR is the first national-level, multicentric clinic-based registry focusing on youth-onset diabetes in India, aiming to understand the disease patterns and variations in youth-onset diabetes across different country regions.

Results

Key operations at the MDRF biobank include collecting and processing samples, where serum and whole blood samples are aliquoted and transferred through a cold chain to the central laboratory, and then stored in Siruseri (29 km from the capital city of Chennai, Tamil Nadu). Samples are barcoded, linked to subject information, and stored in freezers or liquid nitrogen (LN2) vessels, with inventory tracked via software for easy retrieval. A register records access to the biobank, ensuring sample integrity and compliance with regulatory requirements. The biobank adheres to the ICMR’s National Ethical Guidelines for Biomedical and Health Research involving human participants.

Interpretation & conclusions

The biobank enables the analysis of biomarkers in stored samples, aiding in scientifically sound decisions, treating patients, and potentially curing diabetes.
Pons herniation after skull base chondrosarcoma surgery: A rare complication after transclival endoscopic endonasal approach
Authors: Almeida Lucas Costa , da Silva Alice Caroline Alves , de Almeida Matheus Assis , Gonçalves Paulo Eduardo , Oliveira Arthur Maynart Pereira
Published: December 2024

Background:

Intracranial chondrosarcomas are malignant tumors that most commonly affect the clivus region. For tumors in this location, the extended endoscopic endonasal approach could offer an alternative route. We present a case of pons herniation after this technique.

Case Description:

A 55-year-old female presented with a 6-month history of difficulty walking. The neurological evaluation showed asymmetric tetra paresis and involvement of the IX cranial nerve on the right side. Imaging exams showed a lesion at the upper clivus, with a possible diagnosis of chondrosarcoma. An extended transclival approach with partial resection and a multilayer closure were performed. The patient had a slight immediate improvement in muscle strength, and she was discharged home 5 days after surgery. Four weeks later, she evolved with worsening strength on the left side. A new image examination revealed an atypical protrusion of the pontine tissue through the bone defect at the opening of the clivus; a surgical revision was proposed, but the patient chose conservative management.

Conclusion:

Pontine herniation is a rare complication with no defined cause. The use of a rigid material for closure could reduce the chances of this complication, but futher studies are necessary to reinforce that hypothesis.
Oyunların Büyüsü Eğitimle Buluşuyor: Eğitim Programlarını Oyunlaştırma ile Zenginleştirmek
Authors: Şen Egemen , Şahin Hatice
Published: December 2024

Bu çalışmada, oyunlaştırmanın eğitim programlarını geliştirmedeki rolü incelenmektedir. Oyunlaştırma, oyun elementleri ve tasarım tekniklerinin oyun dışı alanlara, özellikle eğitime uygulanması olarak tanımlanır. Çalışma, oyunlaştırmanın öğrenci motivasyonu, katılımı ve öğrenme çıktıları üzerindeki etkilerini değerlendirmeyi amaçlamaktadır.

Literatür taraması kapsamında, oyunlaştırmayı destekleyen eğitim teorileri (yapılandırmacılık, davranışçılık, sosyal öğrenme teorisi) ve motivasyon teorileri (öz-belirleme teorisi, akış teorisi) incelenmiştir. Oyunlaştırmanın tarihsel gelişimi ve teknolojik ilerlemelerle birlikte eğitimdeki uygulamaları ele alınmıştır. Puanlar, rozetler, liderlik tabloları gibi yaygın oyunlaştırma elementleri ve anlatı kullanımı gibi stratejiler detaylandırılmıştır.

Çalışma, oyunlaştırmanın öğrenci motivasyonunu artırdığını, katılımı teşvik ettiğini ve öğrenme çıktılarının iyileştirilmesine katkı sağladığını ortaya koymaktadır. Farklı eğitim seviyelerinde (ilköğretim, ortaöğretim, yükseköğretim) oyunlaştırmanın uygulanma biçimleri ve etkileri incelenmiştir. Teknolojik platformlar ve araçların (özel oyunlaştırma yazılımları, mobil uygulamalar, öğrenme yönetim sistemleri) oyunlaştırmanın etkinliğine nasıl katkıda bulunduğu değerlendirilmiştir.

Ayrıca, oyunlaştırmanın potansiyel dezavantajları ve sınırlamaları, etik ve kültürel bağlamlarda tartışılmıştır. Gelecekteki eğilimler arasında artırılmış gerçeklik (AR), sanal gerçeklik (VR) ve yapay zeka (AI) gibi yeni teknolojilerin entegrasyonu vurgulanmıştır.

Sonuç olarak, oyunlaştırmanın eğitim programlarını geliştirmede güçlü bir araç olduğu, ancak etkili bir uygulama için stratejik planlama, eğitici eğitimi ve teknolojik altyapının önem taşıdığı belirtilmiştir. Gelecekteki araştırmaların, oyunlaştırmanın uzun vadeli etkilerini ve farklı öğrenci grupları üzerindeki sonuçlarını daha derinlemesine incelemesi önerilmektedir.
САРАЧАН-ЮРТ: ПРАВДА, ГИПОТЕЗЫ И ВЫМЫСЕЛ (К 205-ЛЕТИЮ ГОРОДА ГРОЗНОГО)
Authors: И.Д. ХАБАЕВ
Published: December 2024

Статья посвящена истории и этимологии аула Сарачан-Юрт, основанного на правом берегу р. Сунжа задолго до строительства крепости Грозная. На основании исторических материалов установлена локация населенного пункта и тайповая принадлежность его основателей. Автор опровергает утверждение о наречении Сарачан-Юрта в честь коменданта крепости Грозная с 1825 по 1827 г. полковника Т.В Сорочана. Представлены авторские версии этимологии названия Сарачан-Юрт.

The article is devoted to the history and analysis of the etymology of the aul Sarachan-Yurt, founded on the right bank of the Sunzha River long before the construction of the Groznaya fortress. Based on historical materials, the author establishes the location of the settlement and the taip affiliation of its founders. The author refutes the statement about naming Sarachan-Yurt in honor of the commandant of the fortress Groznaya from 1825 to 1827 Colonel T.V. Sorochan. The author's versions of the etymology of the name Sarachan-Yurt is presented.
К ВОПРОСУ О СОЦИАЛЬНОЙ СТРУКТУРЕ ЧЕЧЕНЦЕВ-ОКОЧАН ТЕРСКОГО ГОРОДА В XVII В. (ПО МАТЕРИАЛАМ ДОКУМЕНТА 1640 г.)
Authors: Т.М. МАГОМАДОВА
Published: December 2024

В статье рассматривается начало феодализации горской знати, роли Терского города в социально-экономической жизни края. Поставлена задача раскрыть хотя бы в общих чертах, опираясь на «Роспись» и ряд других источников, социальный статус самой престижной части окочан, их довольно активную деятельность в жизни Терского города в сношениях с Москвой; показано, как русская администрация осуществляла свою политику, привлекая членов феодальных семей. Опираясь на один из документов 1640 г., в статье представлены два феодальных клана чеченской диаспоры (окочан) – мурзы Кохостровы и первостепенные уздени Алеевы. Документы свидетельствуют, что жизнь ококов, втянутых в ритм городской разносторонней и разноэтнической жизни, мало чем отличалась от жизни других жителей города Терки и его слободок. Терские окочане принимали самое непосредственное участие во всех важных событиях, происходивших в городе Терки.

The article discusses the beginning of the feudalization of the mountain nobility, the role of the Terek city in the socio-economic life of the region. The author sets the task of revealing at least in general terms, based on the «Painting» and a number of other sources, the social status of the most prestigious part of the okokans, their rather active work in the life of the Terek city in relations with Moscow; to show how the Russian administration carried out its policy, attracting members of feudal families. Based on one of the documents of 1640, the article presents two feudal clans of the Chechen diaspora (okokans) – the Murzas Kokhostrovs and the primary Uzdens Aleevs. The documents indicate that the life of the okuks, drawn into the rhythm of the city's diverse and multi-ethnic life, was not much different from the life of other residents of Terka and its settlements. The Terek okokans took the most direct part in all the important events that took place in the city of Terka.
АТАЛЫЧЕСКИЕ И РОДСТВЕННЫЕ СВЯЗИ ГИРЕЕВ И КАБАРДИНСКОЙ ЗНАТИ В ПРОСТРАНСТВЕ РУССКО-КРЫМСКО-КАБАРДИНСКИХ ОТНОШЕНИЙ (СЕРЕДИНА ХVIII В.)
Authors: Д.В. СЕНЬ
Published: December 2024

Статья посвящена изучению аталыческих и родственных связей между кабардинской знатью и различными ветвями династии Гиреев. Актуальные вопросы изучения подобных традиционных связей представлены на фоне случая, связанного с пребыванием в Кабарде в конце 1740-х – начале 1750-х гг. двух сыновей султана Арслан-Гирея (в 1748–1755 гг. – правящего крымского хана). К решению данного непростого вопроса оказались причастны Россия, Крымское ханство и Османская империя, причем соответствующие практики заняли в общей сложности не менее пяти лет. Описанный в статье такой случай рассмотрен на фоне как противоречий среди кабардинских элит, так и изменившегося после 1739 г. международного статуса Кабарды. Приведены новые данные о матримониальных связях одной из ветвей ханской династии Гиреев (султана Бахты-Гирея и его детей) с кабардинской знатью. Они, в свою очередь, вписаны автором в пространство традиционных социокультурных практик кабардинской знати с Крымским ханством, выгодных обеим сторонам и актуальных еще для середины XVIII в.

The article is devoted to the study of Atalyk’s (artificial kinship) and family relations between the Kabardian nobility and various branches of the Girey dynasty. Current exploring problems of these traditional connections are presented at the context of a case associated with the staying in Kabarda in the late 1740s – early 1750s two sons of Sultan Arslan-Girey (ruling Crimean Khan in 1748–1755). Russia, the Crimean Khanate and the Ottoman Empire participated in solution of this difficult case, and the relevant processes during five years at least. This described case is considered the background of both contradictions among the Kabardian elites and the international status of Kabarda that changed after 1739. New data are given on the matrimonial relations of one of the branches of the Khan dynasty of Girays (Sultan Bakhty-Giray and his children) with the Kabardian nobility. They are inscribed by the author in the space of traditional socio-cultural practices of the Kabardian nobility with the Crimean Khanate, beneficial to both sides and relevant for the middle of the XVIII century.
ГЕОГРАФИЧЕСКИЕ СВЕДЕНИЯ О СЕВЕРНОМ КАВКАЗЕ В ИЗДАНИЯХ КОИРГО (XIX В.)
Authors: З.Ш. ГАГАЕВА
Published: December 2024

В статье рассматриваются вопросы истории развития географических исследований и их отражение в изданиях Кавказского отдела Императорского Русского географического общества в XIX в. Показано, что издательская деятельность Кавказского отдела имела огромное значение в распространении результатов научных исследований не только в России, но и за ее пределами. Показано, как менялись содержание и значение результатов исследований в изданиях Кавказского отдела: от случайных, разрозненных сообщений до систематических, детальных и регулярных. Отмечается роль отдельных исследователей, в том числе сыгравших важную роль в становлении и развитии кавказоведения.

The article examines the history of the development of geographical research and its reflection in the publications of the Caucasian Department of the Imperial Russian Geographical Society in the 19th century. It is shown that the publishing activities of the Caucasian Department were of great importance in disseminating the results of scientific research not only in Russia, but also abroad. It is shown how the content and significance of the research results in the publications of the Caucasian Department changed: from random, scattered messages to systematic, detailed and regular ones. The role of individual researchers is noted, including those who played an important role in the formation and development of Caucasian studies.
PM6-ML: The Synergy of Semiempirical Quantum Chemistry and Machine Learning Transformed into a Practical Computational Method
Authors: Nováček Martin , Řezáč Jan
Published: December 2024

Machine learning (ML) methods offer a promising route to the construction of universal molecular potentials with high accuracy and low computational cost. It is becoming evident that integrating physical principles into these models, or utilizing them in a ∆-ML scheme, significantly enhances their robustness and transferability. This paper introduces PM6-ML, a ∆-ML method that synergizes the semiempir- ical quantum-mechanical (SQM) method PM6 with a state-of-the-art ML poten- tial applied as a universal correction. The method demonstrates superior perfor- mance over standalone SQM and ML approaches and covers a broader chemical space than its predecessors. It is scalable to systems with thousands of atoms, which makes it applicable to large biomolecular systems. Extensive benchmarking confirms PM6-ML’s accuracy and robustness. Its practical application is facili- tated by a direct interface to MOPAC. The code and parameters are available at https://github.com/Honza-R/mopac-ml.
Improved description of environment and vibronic effects with electrostatically embedded ML potentials
Authors: Zinovjev Kirill , Curutchet Carles
Published: December 2024

Incorporation of environment and vibronic effects in simulations of optical spectra and excited state dynamics is commonly done combining molecular dynamics with excite state calculations, which allows to estimate the spectral density describing the frequency-dependent system-bath coupling strength. The need for efficient sampling, however, usually leads to the adoption of classical force fields, despite well-known inaccuracies due to the mismatch with the excited state method. Here we present a multiscale strategy that overcomes this limitation by combining EMLE simulations based on electrostatically embedded ML potentials with the QM/MMPol polarizable embedding model to compute the excited states and spectral density of 3-methyl-indole, the chromophoric moiety of tryptophan that mediates a variety of important biological functions. Our protocol provides highly accurate results that faithfully reproduce their ab initio QM/MM counterparts, thus paving the way for accurate investigations on the interrelation between the timescales of biological motion and the photophysics of tryptophan and other biosystems.
Learning descriptors to predict organic structure-directing agent applicability in zeolite synthesis
Authors: Hoffman Alexander , Xie Mingrou , Gómez-Bombarelli Rafael
Published: December 2024

Zeolite synthesis frequently relies on organic structure-directing agents (OSDAs), but the process of identifying the best OSDA to synthesize a given zeolite remains difficult. We use previously gathered binding energy data, in additional to the formation energies of the siliceous zeolite frameworks and approximate binding entropies of OSDAs to develop new descriptors to improve predictions based on known OSDA-zeolite pairs in the literature. Our earlier work used templating energy (Eij,T) to rank the most likely OSDA-zeolite pairs to be produced from synthesis. Using literature recall area-under-the-curve (AUC) as a performance metric, we find that computing energies associated with the net transformation that occurs during zeolite synthesis (the sum of the formation energy of the zeolite framework and the OSDA binding energy) provides a modest improvement over Eij,T when predicting the zeolite phase that a given OSDA produces, from 67.5% average literature recall to 72.3%, but negligibly improves predictions for the best OSDA for a given zeolite framework, from 68.3% to 68.8%. We then use machine learning symbolic regression to develop a new descriptor, which we call αij,T, that slightly improves upon Eij,T for predicting an OSDA for a given framework, with an average literature recall of 71.8%. While zeolite synthesis remains difficult to predict a priori, the approaches used in this work provide one option for improving these predictions.
Electrostatic interaction between SARS-CoV-2 and charged surfaces: Spike protein evolution changed the game
Authors: Domingo Marc , Guzman Horacio , Kanduc Matej , FARAUDO JORDI
Published: December 2024

Previous works show a key role of electrostatics for the SARS-CoV-2 virus in aspects such as virus-cell interactions or virus inactivation by ionic surfactants. Electrostatic interactions depend strongly on the variant since the charge of the Spike protein (responsible for virus - environment interactions) evolved across the variants from the highly negative Wild Type (WT) to the highly positive Omicron variant. The distribution of the charge also evolved from diffuse to highly localized. These facts suggest that SARS-CoV-2 should interact strongly with charged surfaces in a way that changed during the virus evolution. This question is studied here by computing the electrostatic interaction between WT, Delta and Omicron Spike proteins with charged surfaces using a new method (based on Debye-Huckel theory) that provides efficiently general results as a function of the surface charge density σ. We found that the interaction of the WT and Delta variant spikes with charged surfaces is dominated by repulsive image forces proportional to σ2 originated at the protein/water interface. On the contrary, the Omicron variant shows a distinct behaviour, being strongly attracted to negatively charged surfaces and repelled from positively charged ones. Therefore, the SARS-CoV-2 virus has evolved from being repelled by charged surfaces to being efficiently adsorbing to negatively charged ones.
Peptide Backbone Cleavage and trans-Amidation via Thioester-to-Imide Acyl Transfer
Authors: Gless Bengt Herbert , Schmied Sabrina , Olsen Christian Adam
Published: December 2024

Cysteine thioesters are involved in a myriad of cen-tral biological transformations because of their unique reactivity. Despite their well-studied proper-ties, we discovered an unexpected trans-amidation reaction of cysteine thioesters that leads to peptide backbone cleavage. S-Acylcysteine-containing pep-tides were found to spontaneously fragment by cleavage of the amide bond in the i-1 position to the acylated cysteine residue at pH 8–10. We pre-sent compelling evidence for a mechanism involv-ing a central reversible thioester-to-imide acyl transfer step. The discovered trans-amidation reac-tion was found to be highly sequence dependent and was found to proceed in peptides containing post-translational modifications (PTMs) such as cysteine S-acetylation and S-palmitoylation as well as in peptide–peptide branched thioesters, mimick-ing class I intein splicing. Thus, the inherent reac-tivity of peptide backbones containing S-acylcysteine residues should represent a starting point for investigation of endogenous protein be-havior and may serve as a foundation for the dis-covery mild new peptide and protein transfor-mations.
Preliminary phytochemical evaluation of methanol extracts of momordica dioica roxb
Authors: Tanneeru Pushpalatha , Ramachandran Dr. Kalpana , Parimala Dr.K. , Joseph Dr. Leena Dennis , Gayathri Dr.V.
Published: December 2024

Momordica dioica, commonly known as spiny gourd, teasle gourd, or kakrol, is a perennial, dioecious climbing plant belonging to the Cucurbitaceae family. This versatile plant is not only used as a food source but also plays a role in preventing and treating various illnesses. The current study focuses on the phytochemical analysis of Momordica dioica, investigating its potential medicinal properties. The fruit is extracted in stages using methanol, after which the presence of key phytochemicals—such as flavonoids, phenolic compounds, tannins, saponins, phytosterols, triterpenoids, and quinones—is screened. The results indicate that this plant is a rich source of diverse phytochemicals. This experimental investigation has identified several biologically active secondary metabolites, which may contribute to the development of new drugs. Overall, Momordica dioica shows promise for future research in pharmacology and nutrition, highlighting its significance in both traditional and modern medicine.
Scientific Heritage of the Scientist-koreaist Igor Alekseyevich Hegay: Pages of Memory
Authors:   Baikal State University, Foygel E. I. , Kazarin V. N. ,   Baikal State University
Published: December 2024

The main milestones of the biography and scientific heritage of the scientist-koreaist I. A. Hegay are considered. Its contribution to studying an ethnic question in Siberia at a boundary of the 19th–20th centuries is noted. The research I. A. Hegay of the reasons and stages of the Korean emigration to Russia, China and the USA is shown. Names of many political refugees, participants of various anti-Japanese societies are revealed. Gave special attention of I. A. Hegay to studying the centers of the Korean emigration in the Far East, armed struggle and cultural and educational activity of emigrants in Russia and China. Authors drew a conclusion on value of researches of I. A. Hegay in the field of studying history of Korea.
Pages of the Economic and Demographic History of the Chinese Northeastern City of Shenyang (Second Half of the 20th – Beginning of the 21st Century)
Authors:   Institute for Demographic Research FCTAS RAS, Makeeva S. B.
Published: December 2024

The article presents the main vectors of the economic and demographic history of the Chinese northeastern city of Shenyang during the first five-year plans after the founding of the PRC, the implementation of the policy of “reform and openness”, modernization and transformational transformations of Chinese society at the turn of the 20th–21st centuries. The author traces the influence of the dynamics of national Chinese politics on changes in the national economic complex of Shenyang and the situation of the population of this northeastern city.
“...Interesting Touches of Modern Life”, or Diary of an Irkutsk Librarian
Authors:   Irkutsk State University, Ivanov A. A.
Published: December 2024

The article examines the diaries of the Irkutsk librarian Nita Stepanovich Romanov (1871– 1942), published by the State Archives of the Irkutsk Region. N. S. Romanov is known to Irkutsk residents primarily as a compiler of chronicles of the city. At the same time, being first the head of the Irkutsk Public Library, and then an employee of the scientific library of Irkutsk State University, he kept a diary throughout his adult life, in which he recorded in detail his actions and thoughts. Along with the author’s inner world, Romanov’s diaries contain a lot of information about city events, revealing the difficult everyday life of Irkutsk residents, which makes them a very valuable source on the history of the socio-economic and cultural life of Irkutsk in the 1920s–1930s.
Automatic Colorizing Black and White Image System Using Deep Learning
Authors:   Dept. of Information Technology  Greater Noida Institute of Technology(Engg.Institute) Greater Noida, Uttar Pradesh, INDIA, Singh Archana , Choubey Ashutosh ,   Dept. of Information Technology  Greater Noida Institute of Technology (Engg.Institute) Greater Noida, Uttar Pradesh, INDIA, Kumar Anant ,   Dept. of Information Technology  Greater Noida Institute of Technology(Engg.Institute) Greater Noida, Uttar Pradesh, Singh Ashvani ,   Dept. of Information Technology  Greater Noida Institute of Technology (Engg.Institute) Greater Noida, Uttar Pradesh
Published: December 2024

Colorization involves transforming a grayscale (black-and-white) image into a colorized version that reflects the semantic color tones of the original input. Over recent years, this process has garnered substantial attention, with significant advancements achieved by researchers in the field. The technique has numerous applications, such as in medical imaging and the restoration of historical artifacts. Various methods have been developed to address this challenge, leveraging technologies like Convolutional Neural Networks (CNNs) and Generative Adversarial Networks (GANs). These models differ in their architectural frameworks and are evaluated using diverse datasets. This paper explores some of these methodologies, comparing the performance of generative models with traditional deep neural networks, while also highlighting existing limitations. Additionally, it provides a concise overview of past and current progress in the domain of image colorization, drawing on contributions from numerous researchers and studies. a widely recognized deep learning algorithm. The proposed model processes grayscale images as input and predicts their corresponding colors based on training data. The Lab color space is employed in this approach, where the model receives the L channel (lightness) as input and predicts the ab channels (color information) as output. A subset of the ImageNet dataset was used for training and evaluation, consisting of 39,604 randomly selected images, divided into 80% for training and 20% for testing.
Ecological infrastructure and its role in sustainable urban development: analysis and perspectives
Authors: Tertytskyi Ie. P.
Published: December 2024

Purpose. To systematize and analyze contemporary scientific research and publications on the topic of ecological infrastructure in the context of sustainable urban development. The main goal is to define the concept of "Ecological Infrastructure" and its interrelation with the concept of sustainable development, as well as to identify key sustainable development goals that can be achieved through optimizing ecological infrastructure.

Results. This article explores the significance of ecological infrastructure (EI) for sustainable urban development, various definitions of "ecological infrastructure" and its use in scientific research in Ukraine and globally. The role of EI in reducing cities' impact on climate change and their adaptation to extreme weather conditions is identified. The article examines key components of EI such as green infrastructure (parks, gardens, forests) and blue infrastructure (water bodies), emphasizing their importance in providing ecosystem services and improving residents' quality of life. Global experiences in EI utilization are analyzed, highlighting diverse approaches and practical applications of these concepts in developed countries. It is worth noting that there is rapid development in EI research worldwide, focusing on developing green spaces to support ecological resilience of cities in modern urbanization conditions.

Conclusions. The development and implementation of urban environment projects focused on ecological infrastructure are crucial steps towards achieving sustainable development goals. Key aspect of using the EI concept is to ensure sustainable urban development, and consequently reducing cities' environmental impact, include the organic integration of natural habitats into urbanized areas, design, and implementation of both traditional and innovative approaches to reduce the city's footprint on ecosystems and the environment. Thus, the scope of issues requiring further research on EI includes optimizing its impact on achieving sustainable development goals and engaging with local communities to meet the needs of all population groups.
Environmental and toxicological assessment of the water quality of Burshtynska TPP cooling reservoir
Authors: T. L. Rychak T. L. Rychak , Arkhypova L. M.
Published: December 2024

Purpose. Determination of the ecological and toxicological assessment of the water quality of the cooling reservoir of the Burshtyn TPP, which is a component of the Galicia National Nature Park.

Methods., Field research, analytical, biotesting, statistical.

Results. The assessment was carried out on the basis of the results of determining the toxic properties of water samples. Water samples were taken in the winter of 2024 in the Burshtyn Reservoir, located on the Hnyla Lypa River. The levels of chronic water toxicity were determined using the biotesting method for the crustacean Ceriodaphnia affinis Lilljeborg. The obtained results show that 50% of the samples taken showed chronic toxicity, namely, samples from the samples taken on the coast of the reservoir within the city of Burshtyn, from the recreational area of the reservoir used by the local population for swimming and recreation, and the area of the reservoir within c. Demyaniv, which is also under the influence of the highway, fish farming. The left bank of the reservoir and the confluence of the Gnyla Lypa River into the reservoir - the first class of water quality has been established in this area and the water is defined as clean according to the degree of pollution. The right bank of the reservoir, which is within the limits of the influence of the highway, excess recreational influence, inflow of surface runoff from the city of Burshtyn, has lower water quality indicators, characterized as the second class of water quality, and according to the degree of pollution, the water is defined as slightly polluted. In other representative bodies, the selected water samples met the standard of water quality according to the toxicological indicator - the absence of chronic water toxicity.

Conclusions. It was established that the left and right banks of the Burshtyn Reservoir are subject to different technogenic loads, different parts of the reservoir are subject to different levels of influence from different sources of pollution and, as a result, have different water quality classes. It is necessary to continue monitoring studies to increase the level of environmental safety of water bodies within the influence of the thermal power plant in terms of increasing control structures.
Simulation modeling tools in training environmental science students
Authors: Kot А. G. , Achasov A. B. , Seliverstov O. Yu. , Karpov V. G.
Published: December 2024

The use of computer modeling and forecasting for the analysis and prediction of complex systemic processes, particularly in the field of environmental protection, is extremely important. For students of ecological specialties, proficiency in modeling is a key aspect. There are at least two computer simulation programs available on the market with free versions for student education: VensimPLE and AnyLogicPLE. They enable the use of simulation modeling and system dynamics for analyzing and predicting ecological processes. Students are provided with the opportunity to create and study various scenarios using mathematical models. Students are encouraged to create and investigate the "Predator Prey" model, which is based on the Volterra-Lotka system of differential equations. The model describes the dynamics of predator and prey populations in a closed and stationary system. Based on equations that consider the reproduction and mortality of both species, students need to explore the interaction between populations under different input parameters. The model has two stages: initially, accumulators with initial population values are created, then parameters regulating flows are added. Using the example of the provided model, the possibility of studying the impact of various factors on ecosystem dynamics and understanding it more deeply is highlighted.

Conclusions. The application of system dynamics methodology allows for the construction of strategic simulation models necessary for making management decisions in the field of environmental protection and rational resource use. This is important for the practical application of students' knowledge in their future professional activities. Such skills will help them effectively influence the state of the environment and make informed decisions regarding its conservation
Еffect of unemployment and inflation on Nigerian economic growth: a time-series analysis
Authors: Adewale A. A. , Adeyemo A. A.
Published: December 2024

This study investigates the effect of unemployment and inflation on economic growth in Nigeria from 1999 to 2021. Employing econometric techniques such as descriptive statistics, trend analysis, and regression analysis, the study explores the relationships between these variables. Findings reveal a significant positive correlation between inflation and GDP growth, while unemployment exhibits a negative correlation with GDP growth. The analysis explains approximately 54.1% of the variance in GDP growth, highlighting the substantial influence of unemployment and inflation on economic performance. Policy recommendations include measures to control inflation, stimulate job creation, and diversify the economy. By addressing these factors, Nigeria can foster sustainable and inclusive economic growth.
Рrospects of health and medical tourism clusterization in Ukraine
Authors: Bieloborodova Mariia
Published: December 2024

Ukrainian health and medical tourism needs a change in strategic planning approaches due, firstly, to the outdated post-Soviet organization of mass rehabilitation and sanatorium-resort treatment, and, secondly, in connection with the expected changes in the structure of consumers and their advantages, both as a result of the full-scale invasion of the russian federation. The subject of the study is the clustering processes in the field of health and medical tourism of Ukraine. The purpose of the study is to substantiate the methodical approach to the clustering of health and medical tourism based on spatial modeling of the relevant resource and material base. The task of the research: substantiating the main directions of health and medical tourism development; generalization of statistical data on the resource and material base based on the method of cartographic visualization; development of proposals for the activation of cluster processes based on statistical groupings of regions. The following methods were used: abstract (theoretical generalizations, formulation of conclusions), systematic approach, method of structural generalization, statistical grouping, graphic method. The following results were obtained: on the basis of statistical analysis, it was proposed to divide the regions of Ukraine into the following groups: the first - seaside regions, specialization – family and children's recreational and health tourism; the second – Volyn and Carpathian region, specialization - sanatorium-resort and rehabilitation vacation with an emphasis on inbound tourism; the third – capital and central-eastern regions, specialization – medical tourism; the fourth – regions without a pronounced potential for health and medical tourism, in total make up 46.47% of the area. The stages for the clustering policy implementation of health and medical tourism in Ukraine have been developed. Conclusions: to improve the management of health and medical tourism, a clustering tool is proposed. The regions of Ukraine are divided into four groups according to the level of resource and material base development, each of which has a clear specialization and target tourist groups, as well as the direction of strategic development. This improves the strategic promotion of domestic health and medical tourist destinations at the inbound and outbound directions.
ORGANIZAÇÕES NÃO GOVERNAMENTAIS NA EDUCAÇÃO: MAPEAMENTO DE ATUAÇÃO NOS PAÍSES AFRICANOS DE LÍNGUA OFICIAL PORTUGUESA – PALOP
Authors: Araujo Felipe de Souza , Silva Rui da
Published: December 2024

Este artigo apresenta resultados de pesquisa que buscou  mapear as organizações não governamentais que atuam no campo educacional dos Países Africanos de Língua Oficial Portuguesa (PALOP). Utilizando uma abordagem qualitativa e exploratória, o estudo empregou métodos de revisão bibliográfica, análise documental e o software Gephi. Considerando que as ONGs estão em franco crescimento nas suas relações com os governos e os atores privados desde o início do presente século, esta pesquisa identificou 111 ONGs atuantes no campo educacional dos PALOP, classificando-as em sete categorias distintas, destacando-se a interconexão de algumas organizações que operam em múltiplos países do grupo. Sublinha-se a Cooperação para o Desenvolvimento como incentivadoras da atuação das ONGs.
ESTÁGIO SUPERVISIONADO: UM OLHAR PARA A SUBJETIVIDADE DOCENTE
Authors: Andrade Érina Ribeiro
Published: December 2024

A formação inicial de professores envolve muitas questões subjetivas. Nessa perspectiva, a pesquisa apresentada neste artigo objetivou compreender o processo de constituição da subjetividade docente de estagiários de um curso de Licenciatura em Química de uma instituição federal em São Paulo, Brasil. As etapas da coleta de dados incluíram uma sessão de grupo focal com cinco estagiários do curso de Licenciatura em Química no ano de 2019. As análises respeitaram as orientações de Gatti (2005), ampararam-se nos preceitos da análise de conteúdo de Franco (2005) e Bardin, (1977) e tiveram por base a discussão de Novaes (2015, 2020), Sousa e Novaes (2013) e Gonçalves e Sousa (2015) sobre constituição da subjetividade docente, e Pimenta e Lima (2011) sobre estágio e formação docente. Como resultados, foi possível constatar que as experiências, as ações, os desafios, as relações e os contextos em que se desenvolveram os estágios são elementos importantes para a constituição da subjetividade do professor, o que acontece ao longo do seu processo de formação, nas suas experiências e na relação com o outro.
The Dual-Role Identities of Middle Managers as Leaders and Subordinates and the Trickle-Down Effect of Empowering Leadership: A Moderated Sequential Mediation Model Analysis
Authors:   Korean Academy Of Management, Shin Chanhyuk , Oh Jooyeon , Chun Jae Uk
Published: December 2024

This study examined how the dual-role identities of middle managers, as both leaders and subordinates, influence their acceptance of empowering leadership from upper leaders and its transmission to subordinates. Specifically, it explored whether middle managers’ deference toward upper leaders mediates the trickle-down effect of empowering leadership and how leader-role and subordinate-role identities moderate this process. Survey data were collected from 174 executives (upper leaders), 174 team leaders (middle managers), and their 775 subordinates (team members) at Korean companies. The responses were all matched through the chain of command, while response anonymity and confidentiality were ensured. The results showed that upper leaders' empowering leadership was positively associated with middle managers' empowering leadership through their deference to upper leaders. The indirect effect was significant when subordinate-role identity was low and leader-role identity was high. Additionally, middle managers' promotability and leader effectiveness were sequentially mediated by their deference toward upper leaders and empowering leadership, with the indirect effects remaining significant under the same moderation conditions. This study highlights the pivotal role of middle managers' dual-role identities in moderating the trickle-down effect of empowering leadership. It deepens our understanding of how middle managers internalize empowering leadership from their superiors, transmit it to their subordinates, and enhance their promotability and leader effectiveness, ultimately benefiting the organization as a whole.
Examining the Effects of Diversity in Interpersonal Relationships on Creativity and the Moderating Roles of Psychological Safety and Diversity Climate
Authors:   Korean Academy Of Management, Han Kwon Hee , Roh Hyuntak
Published: December 2024

This study aims to explore the impact of intrapersonal diversity, specifically gender diversity in voluntary social relationships, on creativity. While prior research on individual creativity has primarily focused on intrinsic motivation and dispositional characteristics, this study adopts a relational perspective to investigate the influence of diversity in individuals’ social relationships. Unlike traditional diversity research, which often conceptualizes diversity as a group-level structural characteristic, this study focuses on the individual level, specifically the diversity of voluntary social networks, and empirically examines its effects. Additionally, this research takes a contextual approach to analyze when, how, and why intrapersonal relationship diversity affects creativity. Among contextual factors influencing team dynamics, this study focuses on team climate variables, such as psychological safety and diversity climate, as moderators. The hypotheses were tested using a multi-level mixed effect model with a matched sample of 124 supervisor-subordinate dyads from 49 teams across 23 companies. The findings indicate that the hypothesized direct positive relationship between intrapersonal social relationship diversity and creativity was not supported. However, the moderating effects of psychological safety and diversity climate were significant, reinforcing the positive relationship under favorable team conditions. This study contributes to diversity and creativity literature by conceptualizing intrapersonal diversity in social relationships, emphasizing the interaction between individual and contextual factors, and providing practical implications for enhancing creativity in organizational settings.
Determinants of Promoting Assisted Delivery in the Lagdo Health District in Northern Cameroon
Authors: Kami Abdoulahi , Nkondjock André , Socpa Antoine
Published: December 2024

Background: Discrepancies in findings on assisted delivery (AD) in the Northern Cameroun persist. In order to reduce maternal mortality, it is hypothesized that specific determinants may help promote the use of AD. This study aimed to assess the possible association between these determinants and AD.Subjects and Method: A cross-sectional study was carried out on 1,175 postpartum women, in the Lagdo health district from May 10th to June 5th, 2023. A three-stage cluster sampling technique was used. Independent variables included the factors related to AD. The dependent variable was the use or no use of AD. A validated questionnaire was employed to gather information. Data analysis was performed with SPSS software version 25. Frequencies, odds ratios (OR), and corresponding 95% confidence intervals (CI) were calculated. The statistical significance was 0.05.Results: The prevalence of AD was 43.9%. After adjustment for age, educational attainment, and parity, a direct association was detected between AD and funded delivery fees (OR=2.5; 95%CI= 1.95 to 3.40; p<0.001), and the presence of motorcycle taxi driver (OR=1.70; 95%CI =1.31 to 2.19; p<0.001). An inverse relationship was observed between AD and distance to health centers (OR= 0.32; 95%CI = 0.18 to 0.58; p<0.001), and lack of community leaders' involvement (OR=0.45; 95%CI = 0.31 to 0.67; p<0.001).Conclusion: Our findings suggest funding delivery fees, reducing distance to health facilities, and sensitizing women by community leaders may help promote AD.
LEVELS OF PSYCHOLOGICAL CHARACTERISTICS OF YOUNG FOOTBALL PLAYERS
Authors: Romaniuk Maksym
Published: December 2024

Introduction. One of the main directions in sports today is the search and development of
talents at every stage of training. Achieving successful results often occurs under
high psychological pressure, which can harm the holistic development of young
athletes. Therefore, it is important to better understand the psychological state of
athletes in order to increase the effectiveness of their competitive and training
activities.
The aim of the study is to determine the level of psychological characteristics of football players
aged 13-15 years and the relationship between them.
Material and methods: In the process of research, the psychological characteristics of young
football players aged 13-15 years were determined. In order to assess psychological
and physiological anxiety, as well as to assess self-confidence, the Illinois Self
Evaluation Questionnaire was used; the Sports Competition Anxiety Test was used
to determine the level of anxiety of football players in sports competitions; The Task
and Ego Orientation in Sports Questionnaire test was used to determine task
orientation and its orientation. The result in the tests is evaluated in points and
corresponds to a certain level. Mathematical statistics methods were also used.
Results. Determination of the body structure features of 560 athletes of different specializations
based on the consideration of the BSA, BMI and fat content indices made it possible to
establish the belonging of athletes to 27 morphotypes (out of 80 possible), among which
the most common are the morphotypes B2b (29.7% of the total sample), C2b (25.3%), C2c
(9.4%), D3c (6.0%), A2b (5.1%). The number of athletes with the indicated morphotypes
amounted to 75.4% of the total number of examined athletes.
Conclusions. The results of the study show that the majority of football players aged 13-15
years have an average level of psychological anxiety (56.8%), while physiological
anxiety is more evenly distributed: 47.3% have a low level and 45.9% have an
average level of anxiety. The vast majority of football players have a high level of
self-confidence (85.1%), and the average level of anxiety in sports competitions is
observed in 54.1% of football players. Most football players have an average level
of task orientation (63.5%), while 60.8% have a high level of ego orientation. This
indicates the importance of psychological characteristics for the development and
success of young football players.