bluuebunny/crossref_metadata_2025 huggingface dataset:
Characterization of Monoolein Liquid Crystals Using Oscillatory Rheology and Strain Rate Frequency Superposition
Authors:   Ryerson University, Mistry Shweta , Fuhrmann Philipp ,   Ryerson University, Rousseau Dérick ,   Ryerson University
Published: July 2022

Glycerol monooleate (GMO) is a commonly used surfactant in the food and pharmaceutical industries. The admixture of GMO and water can form liquid crystals (LCs) with a controllable microstructure upon changes in temperature or GMO:water ratio. Our research hypotheses are that (a) the LC phase directionality dominates the yielding and large deformation behaviour of LCs and that (b) strain-rate frequency superposition (SRFS) may be used to directly measure both the long and short relaxation time of GMO-water LC structures. The microstructure and rheology of GMO-based LCs were characterized as a function of temperature and composition. The structure was assessed using X-ray scattering and polarized light microscopy. Small and large deformation rheology was determined using frequency and amplitude sweeps as well as large amplitude oscillatory shear and SRFS. A binary GMO-water phase diagram was used to identify the presence of lamellar and two cubic phases at temperatures below 65 °C, irrespective of the water:GMO ratio, with a hexagonal phase dominating at higher temperatures. Rheology revealed unique yielding and relaxation times for each of these phases. Via amplitude sweeps, the cubic phases demonstrated a distinct G′′ overshoot that was absent in the lamellar and hexagonal phases. Parameters extracted from the Lissajous plots, namely the stiffening and thickening ratios, provided further insights into their structural deformation. Finally, SRFS showed that these LCs measurably differed in structural relaxation times. We confirmed our hypothesis that each LC phase has unique rheological behaviour upon large deformation and, by linking rheology with X-ray scattering data, showed that their symmetry defined their rheology.
International Standards for Food Authenticity and Allergen Detection from ISO TC 34/SC 16 Horizontal Methods for Molecular Biomarker Analysis
Authors:   ISO/USDA, AMS, L&P, Agricultural Analytics Division, Sussman Michael
Published: July 2022

ISO Technical Committee 34 “Food Products”/Subcommittee 16 “Horizontal methods for molecular biomarker analysis” works to ensure that standardized biomolecular testing and laboratory criteria are reproducible and technically sound reducing potentialdisputes between exporting and importing nations and increasing predictability in world trade. Harmonized, easy to handle methods of analysis with defined patterns and known nomenclatures bring more customers to the market. TC 34/SC 16 has increased international stakeholders’ participation in standardizing biomarker testing, improved the quality and relevance of these standards and continues to increase transparency in international markets, particularly for food authenticity, varietal identification and genetically engineered (GMO) products. ISO standards have been adopted by Codex Alimentarius and many governments throughout the world. The International Organization for Standardization (ISO.org) was formed in 1946. It is an independent, nongovernmental voluntary consensus standard body based in Geneva, Switzerland with a membership of 165 national standards bodies. The US ISO member is the American National Standards Institute (ANSI.org) a consortium of US standardization organizations. ISO TC 34/SC 16 was created in 2008. There are 45 participating countries. Contributing organizations in liaison with TC 34/SC 16 include AOAC International, Cereals and Grains Association, the European Commission, the International Seed Testing Association, the US Pharmacopeia, the European Plant Protection Organization and the International Plant Protection Convention. The scope of TC 34/SC 16 is, "Standardization of biomolecular testing methods applied to foods, feeds, seeds and other propagules of food and feed crops." The US delegation responsible for developing the US position for standards development in food authenticity and allergen detection is called the US Technical Advisory Group (TAG). It was delegated to the American Oil Chemist’s Society (AOCS.org) by ANSI. AOCS also hosts the TC 34/SC 16 international secretariat.
Probiotic Fermentation to Improve Nutritional Profile in Extruded or Ground Corn and Wheat Brans
Authors:   Iowa State University, Byanju Bibek , Lamsal Buddhi ,   Iowa State University
Published: July 2022

Corn bran and wheat bran are coproducts of corn and wheat milling operations, respectively, and have lower commercial value mostly as animal feeds. They are rich sources of dietary fiber and phenolics. In this research, the effect of two physical modifications of wheat and corn brans 1) extrusion at two die temperature settings (140 and 120°C), and 2) grinding to < 500mm were evaluated on fermentation by Lactobacillus plantarum and Bacillus subtillis. Color measurement for extruded brans showed lower L* (lightness) and higher a* and b* (red/green and yellow/blue) when compared with the ground control brans. The diameter of the extruded brans at 25% moisture content was 3.3 mm and 3.49 mm for wheat and corn bran, respectively, compared to 3.0 mm 3.17 mm for wheat- and corn brans at 35% moisture. For fermentation performance, the extruded or ground brans were dispersed in water at 1:10 w/v, pH adjusted to 6.5 and pH 7, autoclaved at 121°C for 30 min, and inoculated (1% v/v) with L. plantarum and B. subtillis, respectively. The fermentation was carried out in 500 mL shake flasks at 37°C for 72 h with shaking at 200 rpm; 10 mL samples were taken out at 0, 6, 12, 24, 48, and 72 h time intervals for microbial viability and pH measurement. All the extruded or ground brans supported the growth of probiotic bacteria, which are expected to modify bran matrix favorably in making dietary/ nutrition components easily available for digestion.
Application of the protective action decision model in land-use scenario analysis for disaster risk reduction
Authors: Shoyama Kikuko
Published: July 2022

Land-Change Science is an emergent field that seeks to enhance understanding of the negative impacts of land use and cover change (LUCC) in order to expedite the development of sustainable resource management and sustainable land use policies. Dr Kikuko Shoyama is a research fellow
at the National Research Institute for Earth Science and Disaster Resilience, Japan, who is conducting research on Land-Use Functions. In her latest project, she is focusing on ecosystem-based disaster risk reduction (Eco-DRR) and she and the team will explore how to utilise Eco-DRR as one
of the Land-Use Functions and look at the type of payment system that is needed to support community activities. This work on designing so-called payment for ecosystem services (PES) involves recognising and valuing the variety of services that ecosystems provide to society. Through PES, an
awareness and appreciation of the value of ecosystems can be cultivated. In her work on Eco-DRR, Shoyama is investigating the effects of land use policies on disaster reduction, with a focus on flood risk information and the impact of policies that promote or inhibit protective behaviour related
to land use. The work involves the use of a hierarchical linear model that extracts the factors affecting protective behaviours by taking into account land ownership and community characteristics. The factors can then be introduced into a land use model and analyses are performed. Ultimately,
Shoyama hopes her work will lead to recommendations that will inform a newer land use strategy and social transformative change.
Elemental composition, mineral characteristics and pedogenesis of serpentine soils in the Western Pacific region
Authors: Hseu Zeng-Yei
Published: July 2022

Soil quality is linked to human health and there is a need to evaluate risks, such as high background levels of chromium (Cr) and nickel (Ni) in serpentine soils. Professor Zeng-Yei Hseu is a world-leading soil scientist working on a three-year project to capture and demonstrate mineral
composition and transformation in serpentine soils. This work will guide remediation techniques for contaminated soils and, in doing so, contribute to food safety and security. Hseu is based at the Soil Survey and Remediation Lab, Department of Agricultural Chemistry, National Taiwan University.
He and his team are seeking to better understand factors such as soil distribution, formation, application and limit. Hseu is interested in phytoremediation, a process through which plants can remove contaminants in the soil and is looking for links between serpentine soils, the plants that
grow in them and their ability to facilitate phytoremediation. He investigated the origin and bioavailability of Cr and Ni and their dynamics in serpentine soils, the risk of Cr and Ni to the food chain and identified that Cr and Ni were mainly released from respective chromites and silicates
of serpentine soils. Hseu is focused on serpentine soils in the Western Pacific region and he and his team collected and analysed serpentine soils from Japan, Taiwan and the Philippines along the western Pacific island arc, as well as from a control site along the Red River Fault Zone in Vietnam.
The researchers looked for the morphology and pedogenesis of different serpentine soils and mineral sources of major and trace elements in the soils.
Blauwvoet op het bord. Feestelijke menukaarten in de Vlaamse beweging (1879-1976)
Authors: Acke Leedert
Published: July 2022

Deze bijdrage toont de uiteenlopende manieren waarop personen en organisaties binnen de Vlaamse beweging menukaarten inzetten voor ideologische doeleinden. Daarvoor wordt niet alleen rekening gehouden met de geserveerde gerechten en hun benamingen, maar ook met het taalgebruik en de versieringen op de kaarten. Hoewel er in sommige gevallen duidelijk gekozen werd voor enkele typisch Vlaamse verwijzingen in de gerechten, was de keuken doorgaans internationaal geïnspireerd, met een sterke dominantie van Frankrijk.
Vlaamsgezindheid bleek veeleer uit de creatieve omgang met de Nederlandse taal op de kaarten, alsook uit de flamingantische leuzen en symbolen die de gerechten soms omringden. Een kosmopolitische feestelijke eetcultuur betekende dus nog niet dat bepaalde individuen niet voor een eigen, Vlaamsgezinde insteek zorgden.

A plate full of Blauwvoet.
Festive menus in the Flemish Movement (1879-1976)

This article analyses the diverging ways in which persons and organizations in the Flemish Movement used menus for ideological purposes, not only taking into account the dishes being served and their names but also the menus’ phrasings and decorations. While in some cases there was a clear preference for typical Flemish references in the dishes, the cuisine in general was internationally oriented, with the French cuisine being very prevalent.
Pro-Flemishness was much more apparent in the creative ways in which the Dutch language was used on the menus, as well as the flamingant slogans or symbols that sometimes adorned the dishes. It highlights how a cosmopolitan festive food culture did not necessarily refrain certain individuals from adding a pro-Flemish twist to the cuisine.
Fabrication and characterization of nanostructured Fe–28Mn–6Si–5Cr shape memory alloy
Authors:   Department of Mechanical Engineering, Periyar Maniammai Institute of Science and Technology, Vallam, India, et al. Bakrudeen
Published: July 2022

Mechanical alloying and consequent sintering techniques were used to create a bulk alloy of Fe–28Mn–6Si–5Cr from elemental powder. The microstructure and shape memory behavior due to bending deformation were investigated. The majority of α phases that existed at the start of the mechanical alloying process were changed into γ phases by the end of the 40-hour process. The γ phase was essential to achieving shape recovery behavior, which was boosted by mechanical alloying. A stress-induced γ to ε phase transformation occurred at the end of the bending deformation process. Shape recovery was observed after the subsequent heat treatment process due to reverse martensitic ε to γ phase transformation. After mechanical alloying, a grain size of 9.5 nm was attained and a considerable amount of shape recovery was achieved at the end of the recovery heat-treatment process. As a result, we came to the conclusion that combining mechanical alloying with powder metallurgy and then sintering has the potential to synthesize Fe-Mn-Si-Cr shape memory alloy.
The Role of Cytochrome P450 2J2 in Cancer: Cell Protector, Therapeutic Target, or Prognostic Marker?
Authors:   Basic Medical Sciences Department, College of Medicine, Ajman University, Ajman, UAE, El-Serafi Ibrahim ,   Experimental Cancer Medicine (ECM), Clinical Research Centre, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden,   Department of Biochemistry, Faculty of Medicine, Port-Said University, Port-Said, Egypt, Oerther Sandra ,   Experimental Cancer Medicine (ECM), Clinical Research Centre, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden,   Clinical research center (KFC), Novum, Karolinska University Hospital-Huddinge, Stockholm, Sweden, Zhao Ying ,   Experimental Cancer Medicine (ECM), Clinical Research Centre, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden,   Clinical research center (KFC), Novum, Karolinska University Hospital-Huddinge, Stockholm, Sweden, Hassan Moustapha ,   Experimental Cancer Medicine (ECM), Clinical Research Centre, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden,   Clinical research center (KFC), Novum, Karolinska University Hospital-Huddinge, Stockholm, Sweden
Published: July 2022

Cytochrome P450 2J2 (CYP2J2) is one of the recently discovered enzymes that is involved in the metabolism of several drugs. It is mainly an extrahepatic enzyme which can, to some extent, explain some the drugs’ side effects such as cyclophosphamide (Cy). Cyclophosphamide is an alkylating agent that is commonly used in conditioning prior to stem cell transplantation. It is a prodrug that is bio-activated by several CYPs including CYP2J2. Cy is known to have several side effects and its extrahepatic activation by CYP2J2 may explain the mechanism of some of these side effects. On the other hand, CYP2J2 is overexpressed in several types of cancer and its inhibition (e.g. by Cy) reduces the cancer cells survival. Taken together, CYP2J2 is considered as a potential therapeutic target and prognostic marker for cancer patients in addition to its role in drugs extrahepatic metabolism.
A Self-management App for People Living With Mild Dementia (PRIDE): Protocol for a Pre-Post Feasibility Study
Authors: Lee Abigail Rebecca , McDermott Orii , Guo Boliang , Roe James , Orrell Martin
Published: July 2022

Background

With the rapid increase in the prevalence of dementia in the United Kingdom and beyond, the emotional, social, and economic burden on individuals, families, and health care services continues to rise. Currently, interventions that enable people living with dementia to better manage their condition and achieve a good quality of life are needed.

Objective

This study aimed to explore how the Promoting Independence in Dementia (PRIDE) app can promote and support the self-management of people living with mild dementia.

Methods

Feasibility of a pre-post study design incorporating the Reach, Effectiveness, Adoption, Implementation, and Maintenance framework will be studied. We will use up to 6 National Health Service Trusts as research sites and the Join Dementia Research website and accept self-referrals to recruit 60 to 90 people living with mild dementia. Participants will complete the PRIDE app intervention over 8 weeks with support from a dementia adviser facilitator. Measures exploring mood, physical well-being, and quality of life will be collected at baseline and at follow-ups at 3 and 6 months. Facilitators and National Health Service staff will be invited to complete interviews shortly after the intervention phase.

Results

Data collection began in June 2021 and is predicted to cease by the end of August 2022. Analysis of the quantitative measures will explore the impact of the PRIDE app on participants’ independence, mood, and quality of life. Interview data will discuss participant experiences, how the use of the app affected them, and if it has the potential to be successfully implemented and maintained in dementia services.

Conclusions

This study will show the potential reach, effectiveness, and adoption of the PRIDE app intervention in the lives of people with mild dementia. The findings from this study will inform future research on the PRIDE app and any further developments to improve its effectiveness.

International Registered Report Identifier (IRRID)

DERR1-10.2196/33881
Retention, Fasting Patterns, and Weight Loss With an Intermittent Fasting App: Large-Scale, 52-Week Observational Study
Authors: Torres Luisa , Lee Joy L , Park Seho , Di Lorenzo R Christian , Branam Jonathan P , Fraser Shelagh A , Salisbury Benjamin A
Published: July 2022

Background

Intermittent fasting (IF) is an increasingly popular approach to dietary control that focuses on the timing of eating rather than the quantity and content of caloric intake. IF practitioners typically seek to improve their weight and other health factors. Millions of practitioners have turned to purpose-built mobile apps to help them track and adhere to their fasts and monitor changes in their weight and other biometrics.

Objective

This study aimed to quantify user retention, fasting patterns, and weight loss by users of 2 IF mobile apps. We also sought to describe and model starting BMI, amount of fasting, frequency of weight tracking, and other demographics as correlates of retention and weight change.

Methods

We assembled height, weight, fasting, and demographic data of adult users (ages 18-100 years) of the LIFE Fasting Tracker and LIFE Extend apps from 2018 to 2020. Retention for up to 52 weeks was quantified based on recorded fasts and correlated with user demographics. Users who provided height and at least 2 readings of weight and whose first fast and weight records were contemporaneous were included in the weight loss analysis. Fasting was quantified as extended fasting hours (EFH; hours beyond 12 in a fast) averaged per day (EFH per day). Retention was modeled using a Cox proportional hazards regression. Weight loss was analyzed using linear regression.

Results

A total of 792,692 users were followed for retention based on 26 million recorded fasts. Of these, 132,775 (16.7%) users were retained at 13 weeks, 54,881 (6.9%) at 26 weeks, and 16,478 (2.1%) at 52 weeks, allowing 4 consecutive weeks of inactivity. The survival analysis using Cox regression indicated that retention was positively associated with age and exercise and negatively associated with stress and smoking. Weight loss in the qualifying cohort (n=161,346) was strongly correlated with starting BMI and EFH per day, which displayed a positive interaction. Users with a BMI ≥40 kg/m2 lost 13.9% of their starting weight by 52 weeks versus a slight weight gain on average for users with starting BMI <23 kg/m2. EFH per day was an approximately linear predictor of weight loss. By week 26, users lost over 1% of their starting weight per EFH per day on average. The regression analysis using all variables was highly predictive of weight change at 26 weeks (R2=0.334) with starting BMI and EFH per day as the most significant predictors.

Conclusions

IF with LIFE mobile apps appears to be a sustainable approach to weight reduction in the overweight and obese population. Healthy weight and underweight individuals do not lose much weight on average, even with extensive fasting. Users who are obese lose substantial weight over time, with more weight loss in those who fast more.
Investigating the Effect of an mHealth Intervention on Health Beliefs, Adherence, and Clinical Outcomes of Patients with Hypertension: Case-Control Study (Preprint)
Authors: Zahed Karim , Markert Carl , Sasangohar Farzan
Published: July 2022

BACKGROUND

Mobile health technologies have shown promise as delivery platforms for digital health coaching to improve self-management of chronic conditions such as hypertension. However, more longitudinal research is required to assess the impacts of such strategies on users’ health beliefs, intentions, and ultimately clinical outcomes.

OBJECTIVE

This study has two main objectives: First, to evaluate the effects of a digital health coaching intervention on participants’ beliefs constructs; and second, to assess the relationships between these belief constructs and intentions to utilize the technological intervention, actual adherence metrics, and clinical outcomes related to hypertension.

METHODS

Thirty-four patients with hypertension were recruited from a large university community from January to May, 2021. They performed self-measurement of weight and blood pressure for 30 days followed by digital coaching delivered via a mobile application for another period of 30 days. Surveys assessed constructs from the Health Belief Model and Technology Acceptance Model, compared to intention, health belief, blood pressure (BP) self-monitoring adherence, and BP outcomes. A path analysis model was used to assess the relationships between constructs and intention, adherence metrics, and clinical outcomes. A Kruskal-Wallis test was used to identify significant changes in beliefs over the course of the intervention.

RESULTS

Participant health beliefs significantly improved as a result of coaching. Namely constructs such as self-efficacy increased (H(1)=15.12, P<.001) from (Mdn=4.75) to (Mdn=6.5), and Cues to Action increased (H(1)=5.33, P=.02) from (Mdn=5.25) to (Mdn=6). Attitude increased (H(1)=10.35, P=.002) from (Mdn=5.95) to (Mdn=6.5). Perceived Usefulness increased (H(1)=15.02, P<.001) from (Mdn=6) to (Mdn=6.5). Resistance to Change decreased significantly (H(1)=4.05, P=.04) from (Mdn=2) to (Mdn=1.25). Adherence to BP measurements positively correlated with perceived health threat (β=.033, P=.007) and perceived ease of use (β=.0277, P<.001). While, Self-efficacy (β =−2.92, P=.02) and perceived usefulness (β =−3.75, P=.01) were linked with a decrease in diastolic BP.

CONCLUSIONS

A digital mobile health coaching intervention may be effective at helping patients with hypertension improve their beliefs regarding the self-management of hypertension. Findings show that there is a significant correlation between self-efficacy and diastolic BP, and higher perceived health threat and perceived ease of use among participants who engaged more with the app.
CLinical utility of the omnigrAf® biomarkeR panel In The care of kidneY transplant recipients: CLARITY Trial Study Protocol (Preprint)
Authors: Fleming James N , Cober Timothy , Hickey Janelle , Stach Leslie , Kawano Allison , Szczepanik Amanda , Watson Alicia , Imamura Yuka , Weems Juston , West-Thielke Patty
Published: July 2022

BACKGROUND

Death with a functioning allograft has become the leading category of graft loss in kidney transplant recipients at all time points. Previous analyses have demonstrated that causes of death in kidney transplant recipients are predominated by comorbidities with strong associations with immunosuppressant medications. Adverse drug events (ADEs) have been strongly associated with nonadherence, healthcare utilization, and graft loss; clinicians face a difficult decision on whether making immunosuppressant adjustments in the face of ADEs will provide improved symptomology or simply increase risk of acute rejection. Clinicians also face a treatment quandary in the 50% of kidney transplant recipients with stage 3 or worse chronic kidney disease at 1-year post-transplant, as progressive decline in renal function has been strongly associated with inferior allograft survival.

OBJECTIVE

The primary objective of the CLARITY Trial is to evaluate change in renal function over time in recipients of kidney transplants who are undergoing OmniGrafTM monitoring in conjunction with patient medication-related burden (MRB) monitoring. A secondary objective is to identify the impact of OmniGrafTM use, in conjunction with patient-reported MRB, as part of clinical care on patient self-efficacy and quality of life (QoL).

METHODS

The CLARITY Trial is a 3-year, prospective, multisite, observational study with a matched control group.

RESULTS

The primary outcome measure of the study will be the comparison of the slope change in estimated glomerular filtration rate (eGFR) from baseline to the end of follow-up between study participants and a matched control group. Secondary outcome measures include changes over time in Patient-Reported Outcomes Measurement Information System (PROMIS) Self-Efficacy for Managing Chronic Conditions – Managing Medications and Treatment-Short Form 4a, the PROMIS-29 Profile v2.1, and PROMIS Depression Scale in the study group, as well as a comparison of hospitalizations and causes, rejections, and graft and patient survival compared between subjects and a matched cohort.

CONCLUSIONS

With this report we describe the study design, methods, and outcome measures that will be utilized in the ongoing CLARITY clinical trial.

CLINICALTRIAL

pending
Application of reinforcement learning in public health: a scoping review of literature (Preprint)
Authors: Awasthi Raghav , Devadiga Akshaya , Gupta Mitali , Tewatia Jeet , Sethi Tavpritesh
Published: July 2022

BACKGROUND

Making public health decisions is arduous due to the multifaceted complexity of data. The advancement of the reinforcement learning (RL) model provides a robust and explainable artificial intelligence framework for making decisions under uncertainty.

OBJECTIVE

This review paper summarizes the extensive research on the reinforcement model in public health applications.

METHODS

This review was done in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Extension for Scoping Reviews (PRISMA-ScR) Statement. From January 2011 to December 2021, electronic databases PUBMED and Google Scholar were routinely searched. Keywords such as exercise, critical care, drugs, diseases, COVID-19, and pandemic were extracted from the articles. Full text, Validation Study, Clinical Study, Observational Study, and case report based on reinforcement learning and public health were included and the articles that did not have a full text available in English were removed.

RESULTS

In the 27 articles reviewed, we observed the application of RL in Public Health in Intervention modeling, Mitigation Policies, Personalised Treatment, and in general complex decision making. Five of the studies that were reviewed dealt with COVID-19, six with critical care and conditions such as Type 2 Diabetes Mellitus, Lung Nodule, Neurocritical, and Neurosurgical Care; five with developing applications for Personalised Healthcare Recommendations, nine with Public Health and measures that can be taken using reinforcement learning, four with emphasizing the future aspects of reinforcement learning and three were review papers.

CONCLUSIONS

The reinforcement learning algorithm, which consists of both off-policy and on-policy algorithms, has been used to make complicated Public Health decisions in Personalised Treatment, COVID-19, Type 2 Diabetes Mellitus, Lung Nodule, Neurocritical, and Neurosurgical Care. As a result, while RL holds great potential for enhancing the effectiveness and efficiency of data-driven decision-making in public health, it is important to acknowledge that this potential impact will necessitate both computational and theoretical advancements as well as a change in how stakeholders view decision-making in intricate healthcare systems.
Retraction of "Assessing the Dissemination of COVID-19 Articles Across Social Media With Altmetric and PlumX Metrics: Correlational Study" (Preprint)
Authors: Tornberg Haley N , Moezinia Carine , Wei Chapman , Bernstein Simone A , Wei Chaplin , Al-Beyati Refka , Quan Theodore , Diemert David J
Published: July 2022

UNSTRUCTURED

REMOVE
Chemical Anchor Pullout Force Modeling with Variation of Anchor Embedment Length in Concrete and Concrete Strength
Authors: Rosyidah Anis , Widiana Putra Jasun , Saputra Jonathan
Published: July 2022

The embedment length influences the adhesion between the cast iron material and the concrete. The concrete's compression strength also contributes to an increase in bond strength. Therefore, this research aims to determine the maximum pullout force on each variation of the anchor and the optimal embedment length. A gauge is modeled as a rod-type with a diameter of 16 mm, and the embedment lengths used are 5D, 10D, and 15D, while the compressive strengths include fc’ 20, 30, 40, 50, and 60 MPa. Furthermore, a finite element-based application was utilized with the ANSYS Workbench student version. The result showed that the concrete with strengths of 20, 30, 40, 50, and 60 MPa has maximum pullout forces of 27.011, 53.536, 68.657, 68.970, and 84.407 kN, respectively at an embedment length of 15D. It was observed that the failure pattern obtained starts from the defect in the concrete cone and ends with the breakage of reinforcement or steel failure at each variation of concrete strength. A combination of two non-parametric techniques was used in this research, which includes Kruskal Wallis and U-Mann Whitney test. The first technique revealed that the chi-square value for strengths 20, 40, 50, and 60 MPa is 9.486, while that of 30 MPa is 9.881. The second test employed showed a significance value below 0.05. In conclusion, the embedment length affected the value of pullout force, and 15D was the optimum embedment length for each variation of concrete strength. The enhancement in tensile strength increases with the strength of the concrete.
Designing a Sales Marketing Model for Generation Z
Authors: Shahbandi Mohammadali
Published: July 2022

In the world of business and the age of information development and the emergence of new information technologies; Generation Z, due to its special feature in the focus component that leads them to a short-range of attention or decentralization and has a sophisticated filter that makes this generation extremely fast and focus on the target content and avoid ads that interest them is not; Special attention has been paid to companies to provide services and products. Born between 2000 and 2014, this new generation has conveyed to managers, business leaders, and marketers that they need to pay more attention to new and faster technologies in order to succeed in working and doing business with the next generation. What makes this generation more important than other generations in marketing; The high population of these consumers and its growing trend around the world and in the United States; Their interest in using new digital technologies towards adults, being digital natives or in other words, synchronizing with this technology almost from birth; Generation Z has a special impact on business and their willingness to buy from ethical and responsible companies and has convinced managers and marketers that in order to reach new customers, it is necessary to consider this new generation more than before and Include in the sales and marketing policies of their products or services.
ANALYTICAL METHOD VALIDATION OF GLICLAZIDE RELATED SUBSTANCES BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD
Authors: T. S. SABHYATHA , BABU NARAYANA
Published: July 2022

Objective: The present study was undertaken with the objective of method validation of a rapid, simple, cost-effective HPLC method for the determination of related substances of Gliclazide.
Methods: A simple, rapid, and specific method for analysis of gliclazide by a sensitive high-performance liquid chromatographic method is described.
Validation of the method is carried out by USP and ICH guidelines. The method was validated for parameters like accuracy, precision, linearity, specificity, robustness, and system suitability. These proposed methods are suitable for the determination of title drugs in quality control laboratories in the pharmaceutical industries.
Results: The mobile phase used for the chromatographic runs consisted of (450 ml) of acetonitrile and (550 ml) of water. The separation was achieved on the LiChroCART Supersher RP-8 column, (250 mm × 4.0 mm, 5 µm), using isocratic mode. Drug peaks were well separated and were detected by a UV detector at 235 nm, the method was linear at the concentration range. Gliclazide limit of detection (LOD) and limit of quantification (LOQ) was 0.003 and 0.01 while LOD and LOQ for Impurity-F were 0.003 and 0.01 respectively.
Conclusion: The presented validated method is rapid, economic, simple, accurate, sensitive, robust, specific, and linear. It can be used for routine analysis of gliclazide.
k-super cube root cube mean labeling of some corona graphs
Authors: Princy Kala V.
Published: July 2022

Let G be a graph with |V (G)| = p and |E (G)| = q and f : V (G) → {k, k+1, k+2,..., p+q+k − 1 } be an one-to-one function. The induced edge labeling f ∗, for a vertex labeling f is defined by f ∗(e) = for all e = uv ∈ E(G) is bijective. If f(V (G)) ∪ {f ∗(e) : e ∈ E(G)} = {k, k+1, k+2,..., p+q+k − 1}, then f is known as a k-super cube root cube mean labeling. If such labeling exists, then G is a k-super cube root cube mean graph. In this paper, I prove that Tn ʘ K1, A(Tn) ʘ K1, A(Tn) ʘ 2K1, A(Qn) ʘ K1, Pn ʘ K1,2 and Pn ʘ K1,3 are k-super cube root cube mean graphs.
On generating functions of modified Jacobi polynomials
Authors: Chongdar Amartya
Published: July 2022

In this paper, the present author has made an attempt to present a generalization of the result on bilateral generating functions involving modified Jacobi polynomials, found derived in [1, 2], by means of the theory of one parameter group of continuous transformations and using the notion of partial quasi bilateral generating function [3] involving some special functions.
Derecho romano II
Authors:   FES Aragón UNAM, Zanicotti Segura David
Published: July 2022

Derecho romano II, nos da un recorrido por los antecedentes de la Ciencia Jurídica en la antigua Roma, mismos que el día de hoy son la base de nuestro sistema jurídico mexicano. Desde delitos hasta sucesiones, esta obra nos muestra la importancia que siempre ha tenido el Derecho en la sociedad, quien indispensablemente requiere de distintas normas para tener una convivencia equilibrada. Asimismo, la obra muestra el cambio que ha tenido la aplicación de justicia a través de los años, siendo esta uno de los pilares de la sociedad
MicroRNAs: Una opción emergente para el diagnóstico y tratamiento de la diabetes mellitus tipo 2
Authors: Mendoza-Soto Ana Belén
Published: July 2022

La diabetes mellitus (DM) es una epidemia creciente que plantea una gran amenaza para la salud mundial. Se estima que actualmente 527 millones de personas alrededor del mundo tienen DM y que en los próximos 25 años la prevalencia mundial aumentará alrededor de un 46%. La DM es una afección grave crónica que ocurre cuando se elevan los niveles de glucosa en la sangre, debido a que el organismo no puede producir suficiente hormona insulina o no la puede utilizar eficazmente.
Los Ovillejos de Sor Juana: las intertextualidades burlescas y su gato encerrado
Authors: Olivares Zorrilla Rocío
Published: July 2022

En este artículo se exploran modelos poéticos de los Ovillejos de sor Juana Inés de la Cruz no analizados antes, pues usualmente son comparados con las fábulas mitológico-burlescas de Salvador Jacinto Polo de Medina y Luis de Góngora. Aparecen en su intertextualidad tres autorretratos burlescos: uno de Góngora, otro de Francisco de Trillo y Figueroa, y uno más de Agustín de Salazar y Torres. El estudio de los Ovillejos transita, así, del género fabulístico al género del retrato burlesco y su itinerario característico, que aparece en el poema de sor Juana recurriendo a las tautologías antimetafóricas de estos últimos, a su constante escarnio de la persona retratada (ellos mismos), a las resonancias de las germanías o —en el caso diferenciado de sor Juana— a un hilo discursivo antipetrarquista. Ubica también —en el lugar del objeto poético desplazado por elusión, Lisarda— no solamente a sor Juana misma como poeta —algo ya señalado por Frederick Luciani—, sino además a la persona misma de sor Juana. Los Ovillejos son, de tal suerte, un autorretrato burlesco.
Students’ Grammatical Problems in Writing Paragraph at Academic Year 2019/2020 of STKIP PGRI Sumatera Barat
Authors: Anwar Syilvi , Siska Siska , Asty Herfyna
Published: July 2022

Penelitian ini dilatar belakangi oleh pentingnya mempelajari grammar dalam menulis, khususnya menulis grammar dalam pengunaan tenses dalam paragraph writing di STKIP PGRI Sumatera Barat untuk mengetahui kesalahan-kesalahan yang dilakukan mahasiswa saat menulis paragraph writing. Penelitian ini merupakan penelitian yang menggunakan metode penelitian descriptive research   dengan pendekatan qualitative research. Peneliti melakukan analisa pada source of data dar iparagraph writing mahasiswa dengan metode pengambilan sampel yaitu purposive sampling. Populasi penelitian ini adalah sebanyak 3 kelas dari program studi pendidikan bahasa inggris tahun ajaran 2019/2020, atau sebanyak 79 data mahasiswadengan instrument yaitu dokumen ceklis. Pengumpulan data dengan cara menganalisa lembar jawaban ujian mid semester mahasiswa sebanyak 79 lembar data. Hasil dari penelitian ini menunjukkan bahwa beberapa mahasiswa memiliki masalah dalam pengunaan grammar khusunya pada tenses yang tidaksesuaidenganaturan tenses itusendiri. Jadipenelitimenyimpulkanbahwa 8 data yang peneliti temukan didalam paragraph writing belum benar berdasarkan rules dari penggunaan tenses itu sendiri.
Kelayakan dan Praktikalitas Media Pembelajaran Thunkable Berbasis Android pada Materi Ketahanan Pangan Industri dan Energi Kelas XI IIS SMAN 1 Painan
Authors: Sandra Heru Kartika , Tanamir Momon Dt. , Afryansih Nila
Published: July 2022

This study aims to determine and analyze the feasibility and practicality of Android-based thunkable learning media on industrial food security and energy materials for class XI IIS SMAN 1 Painan. The type of research used in this research is research and development (Research and Development). With a 4D model that includes 4 stages, namely: Define, Design, Development, Desiminate. The subjects in this study were students of class XI IIS as many as 64 students. The results of the study found that: 1.)Thunkable learning media based on Android is declared very feasible after analyzing data processing using Microsoft Excel so that the total score is 277 with a mean level of 4.85 and a percentage rate of 97% with “Very Eligible” category. 2.) Thunkable learning media based on Android is declared practical after processing the research data obtained from the questionnaire, and a practical test is carried out so that a total score of 2.204 is obtained with a mean level of 4.45 and a percentage of 89% in the "Very Practical" category.  Keywords: Appropriateness, Practicality, Android.
Self-Regulated Learning Behaviors of English Students Through E-Learning at University of PGRI Sumatera Barat
Authors: Utami Marisca Dwi , Sesmiyanti Sesmiyanti , Ikhsan M. Khairi
Published: July 2022

ABSTRAKPenelitian ini bertujuan untuk mengetahui perilaku belajar mandiri mahasiswa Bahasa Inggris tahun ajaran 2017 melalui e-learning di Universitas PGRI Sumatera Barat. Permasalahan yang terjadi pada para mahasiswa pendidikan jarak jauh di antaranya adalah kurangnya motivasi dan penundaan, gangguan dari teknologi, pekerjaan dan keluarga, juga kecenderungan menggunakan metode reaktif daripada metode proaktif. Dalam penelitian ini, peneliti menggunakan desain penelitian deskriptif dengan menggunakan metode campuran. Peneliti mengumpulkan data dengan menggunakan Online Self-Regulated Learning Scale (OSLQ) dan wawancara. Ada 44 mahasiswa yang berpartisipasi dalam penelitian ini. Hasil penelitian menunjukkan bahwa mahasiswa harus meningkatkan keterampilan dan pengetahuan mereka tentang bagaimana mengelola dan meningkatkan antusiasme pembelajaran online mereka.Kata kunci : Perilaku belajar mandiri, E-learning, Pendidikan jarak jauh.
Kelayakan dan Praktikalitas Media Pembelajaran Menggunakan Aplikasi Sparkol Videoscribe terhadap Motivasi Belajar Siswa pada Mata Pelajaran Geografi di SMA N 4 Bukittinggi
Authors: Asmawati Mai Liza , Rianto Slamet , Setriani Loli
Published: July 2022

This study aims to determine and analyze the development, feasibility and practicality of Learning Media Development Using Sparkol Videoscribe on Students' Learning Motivation in Geography Subjects at SMA N 4 Bukittinggi.The type of research used in this research is research and development (Research and Development). The 4D model includes 4 stages, namely: Define, Design, Development, Desiminate. The subjects in this study were students of class XI IPS 1 and Class XI IPS 4 who took part in the geography learning process at SMA N 4 Bukittinggi in the academic year 2021/2022, with a total of 64 students.The results of the study found that: 1.) The development of the sparkol videoscribe learning media included validation from experts, namely media experts, education experts, and linguists. So that the media validation data is obtained and then processed with the Interaclass Coefitien Correlation (ICC) formula assisted by processing using the SPSS version 22 application for Windows, the result is 0.868. if the value is more than 0.5, it can be concluded that the level of validation is adequate. 2.) The sparkol videoscribe learning media was declared very feasible after analyzing data processing using Microsoft Excel so that the total score was 174 with a mean level of 4.37 and a percentage level of 87% with the predicate "Very Good". 3.) The sparkol videoscrieb learning media was declared practical after processing the research data obtained from the questionnaire, and a practical test was carried out so that a total score of 3875 was obtained with a mean level of 4.15 and a percentage of 83% in the "Very Practical" category.  Keywords: Appropriateness, Practicality, Sparkol videoscribe.
Comparison and Contrast in Writing Data Analysis Students Thesis English Department
Authors: Saputri Devita Esa Dewi , Sesmiyanti Sesmiyanti , Sani Riny D.
Published: July 2022

Penelitian ini dilatarbelakangi oleh ketertarikan peneliti untuk mengetahui kekurangan dalam menulis skripsi yang terjadi pada thesis mahasiswa wisuda angkatan 59 Pendidikan Bahasa Inggris di STKIP PGRI Sumatera Barat. Ada beberapa kekurangan yang peneliti temukan dalam thesis siswa pada saat pre observasi seperti ketidaktepatan penggunaan conjunction, transition, cause effect dan comparison contrast namun peneliti hanya fokus pada analisis comparison and contrast pada skripsi mahasiswa. Tujuan dari penelitian ini adalah untuk mengetahui apakah ada penggunaan comparison and contrast dalam skripsi mahasiswa dan menganalisis ketepatan atau ketidak tepatan penggunaan comparison and contrast. Penelitian ini dilakukan dengan menggunakan penelitian kualitatif dengan metode dokumen analisis. Populasi penelitian ini adalah sebanyak 21 skripsi mahasiswa Program Studi Pendidikan Bahasa Inggris STKIP PGRI Sumatera Barat wisuda ke 59. Penelitian ini menggunakan purposive sampling sebanyak 14 skripsi mahasiswa yang telah di analisi. Peneliti menggunakan dokumen analisis sebagai instrument pada penelitian ini. Pengumpulan data dengan cara membaca dan mencari data analisis pada skripsi  mahasiswa wisuda ke 59. Hasil dari penelitian ini menunjukkan bahwa dari 21 skripsi mahasiswa di temukan 14 dokumen yang menggunakan comparison and contrast dan ditemukan penggunaan  yang tepatguna dan tidak tepatguna.
Students Learing Strategies in Intensive Listening Subject at STKIP PGRI Sumatera Barat Academic Year 2020/2021
Authors: Saputri Ninda Lagu , Asty Herfyna , Autilla Rani
Published: July 2022

ABSTRACTPenelitian ini dilatar belakangi oleh ketertarikan peneliti untuk melihat strategi siswa terhadap pembelajaran listening dalam belajar Bahasa Inggris di kampus STKIP PGRI Sumatera Barat. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana strategi siswa terhadap pembelajaran intensive listening dalam belajar bahasa inggris. Penelitian ini adalah penelitian quantitative Descriptive method dengan data yang diambil dari angket persepsi siswa terhadap strategi yang digunakan dalam pembelajaran intensive di kampus STKIP PGRI Sumatera Barat. Jumlah sample dalam penelitian ini sebanyak 67 siswa. Penelitian ini menggunakan purposive sampling dalam pengambilan sample. A structured item questionnaire dan wawancara digunakan sebagai instrument untuk teknik pengumpulan data. Hasil analisa data memperlihatkan bahwa strategi yang digunakan dapat mempermudah siswa dalam memahami pembelajaran. Peneliti menyimpulkan bahwa strategi yang digunakan bagus untuk meningkatkan kemampuan mendengarkan bagi siswa. Kata Kunci: Bahasa Inggris, Listening Strategi, Strategi Belajar
Pengaruh Metode Pembelajaran, Motivasi Belajar dan Lingkungan Sekolah terhadap Hasil Belajar Akuntansi Kelas X di SMK N 1 Sutera Kabupaten Pesisir Selatan Tahun Ajaran 2021/2022
Authors: Gusrel Yulia Sarita , Susanti Nora , Wati Wati
Published: July 2022

This study aims to analyze: 1) To determine the effect of learning methods on the learning outcomes of class X accounting students at SMK N 1 Sutera. 2) To determine the effect of learning motivation on the learning outcomes of class X accounting students at SMK Negeri 1 Sutera. 3) To determine the effect of the school environment on the learning outcomes of class X accounting students at SMK Negeri 1 Sutera. 4) To determine the effect of learning methods, learning motivation and school environment simultaneously affect the learning outcomes of class X accounting students at SMK Negeri 1 Sutera. This type of research is associative and descriptive. The population of this research is accounting students of class X at SMK Negeri 1 Sutera totaling 101 people. The sampling technique used is proportional random sampling with a sample size of 81 people. Data analysis was assisted by SPSS version 15 and eviews version 8. The results of this study indicate that: 1) Learning methods have a positive and significant effect on student learning outcomes. Learning motivation has a positive and significant effect on student learning outcomes. The school environment has a positive and significant effect on learning outcomes. There is a simultaneous influence of learning methods, learning motivation and school environment on learning outcomes, so it can be concluded that Hypothesis 4 is accepted which means there is an influence of learning methods (X1), learning motivation (X2) and school environment (X3). Based on the results of this study, the authors suggest that teachers can provide varied learning methods and make students not bored, suggest students to further increase student learning motivation, it is hoped that in learning, especially in completing the tasks given by the teacher, it should be done faster and not negligently as well as the environment. a clean and good school to take part in learning because the school environment is very important for the learning process.