bluuebunny/crossref_metadata_2025 huggingface dataset:
Overexpression of Circulating Soluble Nogo-B Improves Diabetic Kidney Disease by Protecting the Vasculature
Authors: Hernandez-Diaz Ivan , Pan Jiaqi , Ricciardi Carlo Alberto , Bai Xiaoyan , Ke Jianting , White Kathryn E. , Flaquer Maria , Fouli Georgia E. , Argunhan Fulye , Hayward Anthea E. , Hou Fan Fan , Mann Giovanni E. , Miao Robert Q. , Long David A. , Gnudi Luigi
Published: June 2019

Damage to the vasculature is the primary mechanism driving chronic diabetic microvascular complications such as diabetic nephropathy, which manifests as albuminuria. Therefore, treatments that protect the diabetic vasculature have significant therapeutic potential. Soluble neurite outgrowth inhibitor-B (sNogo-B) is a circulating N-terminus isoform of full-length Nogo-B, which plays a key role in vascular remodeling following injury. However, there is currently no information on the role of sNogo-B in the context of diabetic nephropathy. We demonstrate that overexpression of sNogo-B in the circulation ameliorates diabetic kidney disease by reducing albuminuria, hyperfiltration, and abnormal angiogenesis and protecting glomerular capillary structure. Systemic sNogo-B overexpression in diabetic mice also associates with dampening vascular endothelial growth factor-A signaling and reducing endothelial nitric oxide synthase, AKT, and GSK3β phosphorylation. Furthermore, sNogo-B prevented the impairment of tube formation, which occurred when human endothelial cells were exposed to sera from patients with diabetic kidney disease. Collectively, these studies provide the first evidence that sNogo-B protects the vasculature in diabetes and may represent a novel therapeutic target for diabetic vascular complications.
Pioneerityötä rajakarjalaisen onomastiikan alalla
Authors: Sarhimaa Anneli
Published: June 2019

Arvioitu teos:

Outi Patronen: Rajakarjalaisen sukunimistön kehittyminen osana Suomen karjalankielisen ortodoksivähemmistön suomalaistumista 1818–1920. Helsingin yliopisto 2017. 519 s. isbn 978-951-51-3641-1.
Actualization of Local Wisdom in Anticipating Radicalism of Religion In Gorontalo Indonesia
Authors: Rahmawati Rahmawati , Rusli Muh. , Yahiji Kasim
Published: June 2019

This paper aims to express the values of local wisdom that belong to the people of Gorontalo, Indonesia. The values of local wisdom need to be explored to anticipate the symptoms of religious radicalism that began to emerge in the life of the people of Gorontalo city. Using phenomenology method, this study analyzes the data obtained through interviews, observation, documentation, and focus group discussions. The results of the study show that Gorontalo people have many local wisdom values, such as huyula; dulohupa;Modungohe ta Uda’a; Mopiyohu to bisala wawu huhutu; dan Tombulu. In the local wisdom found the value of mutual cooperation, deliberation, adherence to custom , tolerance, love for the motherland, moral education, self-purification, deepening of Islamic teachings, benevolence, and virtue. This study concludes that Gorontalo people have internal strength as social capital to anticipate the symptoms of religious radicalism.
Eco-Pesantren as A Basic Forming of Environmental Moral and Theology
Authors: Herdiansyah Herdis , Sukmana Hadid , Lestarini Ratih
Published: June 2019

The rising of education with an environmentally friendly approach becomes one of the focuses on implementing sustainable growth of social life. This principle includes an attempt to develop the ecologically friendly pesantren. Along the time, pesantren is identified as a religion and social center. Meanwhile, its surrounding environment has not become the primary priority. This paper sought to analyze the activity of community service related to initiating the perspective change of pesantren. The study implies that pesantren not only an education institute practicing educational activity, but also become an agent of change for creating a better social life and society around, and further, to perform the environmentally friendly pesantren. The research used the literature review approach to propose the Eco-Pesantren strategy, the benefits and social-economic impact for pesantren and the greater community. Moreover, the Eco-Pesantren concept becomes the basis and good characteristic learning with concern for the environment. Furthermore, environmental theology brings Eco-Pesantren on the profound philosophy of eco-ethical perspectives.
NATIONAL SUBSCRIPTION AND LIBRARY ACQUISITION. PART TWO. THE PRINT AND ELECTRONIC BOOK ACQUISITION IN RUSSIA. STRUCTURE OF RUSSIAN MARKETS OF SCHOLARLY INFORMATION
Authors: Razumova I. K.
Published: June 2019

Introduction. The national-level subscription to the global citation indexes Web of Science Core Collection and Scopus and the Freedom Collection of Elsevier released 70% of the electronic acquisition expenditures in the Russian libraries. The article aims at the analysis of the changes in the scope and structure of the book and electronic/print book acquisition budgets in the Russian libraries upon the state-funded national subscription. The article studies changes in the structure of the Russian markets of scholarly information broken in different reference groups.

Materials and Methods. The article employs statistical analysis of the survey results. Materials comprise results of the data processing of the Russian surveys on the acquisition budgets in 2016–2018 and published results of the international surveys. We analyze three main reference groups and four sub-groups of the Russian institutions. Results obtained in Russia are compared with the results for American academics.

Results. Our findings show that the acquisition budgets of Russian institutions demonstrate a shift towards the book and print book acquisition. Both trends differ from the international ones and the 2022 forecasts of the American libraries. The markets of electronic scholarly information show continuous concentration to the segment of universities. In 2018, relative shares of the university segment of the markets of electronic resources and electronic books made correspondingly 94% and 99%. In the electronic book market, the share of the reference group of the universities of the 5/100 project increased from 24% to 32%, whereas the share of two national universities shrank from 24% to 14%.

Discussion and Conclusions. The results obtained probably indicate the effect of the national subscription on the library acquisition. The loss in the market positions of the group of Russian national universities can change leaders in the field of research output.
PENGARUH MODEL PEMBELAJARAN INKUIRI TERBIMBING (GUIDED INQUIRY) TERHADAP HASIL BELAJAR SISWA KELAS X SMA NEGERI 15 MEDAN T.P 2016/2017
Authors: Telaumbanua Agnes Yuniarni , Sihombing Eidi
Published: June 2019

Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran inkuiri terbimbing terhadap hasil belajar siswa kelas X SMA Negeri 15 Medan T.P. 2016/2017. Jenis penelitian ini adalah quasi eksperimen dengan two group pretest-posttest design. Populasi penelitian ini adalah seluruh siswa kelas X MIA Semester II yang terdiri dari 6 kelas. Penentuan sampel dilakukan dengan cara random sampling dengan mengambil dua kelas dari enam kelas yaitu kelas X MIA 1 sebagai kelas eksperimen yang menggunakan model pembelajaran inkuiri terbimbing dan kelas X MIA 6 sebagai kelas kontrol menggunakan pembelajaran konvensional. Instrumen yang digunakan adalah tes hasil belajar yang berjumlah 5 soal dalam bentuk essai yang telah divalidasi, lembar observasi sikap dan lembar keterampilan. Berdasarkan hasil observasi di kelas eksperimen diperoleh rata-rata sikap dan keterampilan siswa dalam kategori baik sedangkan rata-rata sikap di kelas kontrol termasuk dalam kategori cukup baik. Hasil uji hipotesis menggunakan anava satu jalur diperoleh ada pengaruh yang signifikan dari model pembelajaran inkuiri terbimbing terhadap hasil belajar siswa kelas X semester II SMA Negeri 15 Medan T.P 2016/2017 dengan pembelajaran konvensional.Kata kunci : model pembelajaran inkuiri terbimbing, pembelajaran konvensional, hasil belajarPenelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran inkuiri terbimbingterhadap hasil belajar siswa kelas X SMA Negeri 15 Medan T.P. 2016/2017. Jenis penelitian ini adalahquasi eksperimen dengan two group pretest-posttest design. Populasi penelitian ini adalah seluruhsiswa kelas X MIA Semester II yang terdiri dari 6 kelas. Penentuan sampel dilakukan dengan cararandom sampling dengan mengambil dua kelas dari enam kelas yaitu kelas X MIA 1 sebagai kelaseksperimen yang menggunakan model pembelajaran inkuiri terbimbing dan kelas X MIA 6 sebagaikelas kontrol menggunakan pembelajaran konvensional. Instrumen yang digunakan adalah tes hasilbelajar yang berjumlah 5 soal dalam bentuk essai yang telah divalidasi, lembar observasi sikap danlembar keterampilan. Berdasarkan hasil observasi di kelas eksperimen diperoleh rata-rata sikap danketerampilan siswa dalam kategori baik sedangkan rata-rata sikap di kelas kontrol termasuk dalamkategori cukup baik. Hasil uji hipotesis menggunakan anava satu jalur diperoleh ada pengaruh yangsignifikan dari model pembelajaran inkuiri terbimbing terhadap hasil belajar siswa kelas X semesterII SMA Negeri 15 Medan T.P 2016/2017 dengan pembelajaran konvensional.Kata kunci : model pembelajaran inkuiri terbimbing, pembelajaran konvensional, hasil belaja
PENINGKATAN HASIL BELAJAR DENGAN MODEL PROBLEM BASED LEARNING PADA MATERI FLUIDA STATIS
Authors: Manik Erwin , Tampubolon Togi
Published: June 2019

Penelitian ini bertujuan untuk mengetahui pengaruh model problem based learning (PBL) terhadap hasil belajar siswa pada materi pokok Fluida Statis di kelas XI semester II SMA Swasta Raksana Medan T.P. 2017/2018. Jenis penelitian ini adalah quasi exsperiment. Desain penelitian yang digunakan adalah two group pretest-posttest. Populasi dalam penelitian  adalah seluruh siswa kelas XI yang terdiri dari 3 kelas yang dipilih dengan cara teknik random sampling. Kelas XI IPA 1 sebagai kelas eksperimen yang berjumlah 35 orang dan XI IPA 2 sebagai kelas kontrol yang berjumlah 31 orang. Instrumen yang digunakan essai dengan jumlah 8 soal yang telah dilakukan uji persyaratan tes untuk mengukur hasil belajar. Hasil penelitian menunjukkan bahwa nilai rata-rata pretest kelas eksperimen sebesar 11,18 dan kelas kontrol sebesar 11,29. Uji t menunjukkan bahwa kemampuan awal siswa kedua sampel. Nilai rata-rata postes kelas eksperimen  sebesar 77,39 dan kelas kontrol sebesar 68,71. Uji t menunjukkan ada pengaruh yang signifikan akibat penerapan model problem based learning (PBL) terhadap hasil belajar siswa pada materi pokok Fluida Statis.Kata kunci : Problem based learning (PBL), hasil belajar, Fluida Statis
PENGARUH MODEL PEMBELAJARAN INKUIRI TERBIMBING TERHADAP KETERAMPILAN PROSES SAINS SISWA PADA PEMBELAJARAN FISIKA
Authors: Khairuna Khairuna , Panggabean Jonny H.
Published: June 2019

Penelitian ini bertujuan untuk mengetahui keterampilan proses sains siswa dalam proses pembelajaran menggunakan model pembelajaran inkuiri terbimbing dan menggunakan pembelajaran konvensional. Jenis penelitian ini adalah kuasi eksperimen dengan populasi seluruh siswa kelas XI IPA di MAN 2 Model Medan yang terdiri dari 9 kelas. Sampel penelitian diambil 2 kelas dengan random sampling yaitu kelas XI IPA 5 sebagai kelas eksperimen yang diberi perlakuan dengan menggunakan model pembelajaran inkuiri terbimbing dan kelas XI IPA 6 sebagai kelas kontrol yang menggunakan pembelajaran konvesional. Instrumen yang digunakan adalah essai tes sebanyak 8 soal. Hasil analisa data diperoleh nilai rata-rata pretes kelas ekperimen 31.36 dan kontrol 28.73. Pada uji normalitas dan homogenitas kedua kelas berdistribusi normal dan homogen, berarti kedua kelas memiliki kemampuan awal yang sama, kemudian dilakukan perlakuan yang berbeda dan diberikan postes. Hasil analisa data diperoleh nilai rata-rata postes kelas ekperimen 71.49 dan kelas kontrol 60.86. Hasil uji t postes diperoleh kesimpulan bahwa ada pengaruh dari penerapan model pembelajaran inkuiri terbimbing terhadap keterampilan proses sains siswa pada pembelajaran fisikaKata kunci : model problem based learning, suhu dan kalor, kemampuan pemecahan masalah
EFEKTIVITAS MODEL LEARNING CYCLE 7E BERBANTUAN E-MODUL UNTUK MENINGKATKAN KEMAMPUAN BERPIKIR KRITIS PESERTA DIDIK SMP
Authors: Desty Sugiharti Sapta , Supriadi Nanang , Andriani Siska
Published: June 2019

This research aimed to findout the effectiveness of learning cycle 7e assisted e-modul to improve critical thinking skill of Junior High School of students. This research used the quasy experimental design with three classed as sample, VII A as first experiment class, VII B as second experiment class, andVII C as control class. The data were used in this research are the result of pretest and n-gain scores. Data were analyzed by one way Anova and Scheffe test. Based on the result of the Scheffe test, it is knownthe models learning is togive the impact of a diffirent order to enhance the ability of the critical thinking skill. The mean of N-Gain at first experiment class was 0,829, at second experiment class was 0,693, and control class was 0,571. Based on the mean of N-Gain, it can be concluded that learning cycle 7e assisted e-modul was the most effective model to improve critical thinking skill of Junior High School students.
Populus erratica Sachse, nom. nov. – not really new, but a stratigraphically informative species from the late Oligocene and early Miocene of Central Europe
Authors: Sachse Markus
Published: June 2019

A critical review of reports from European localities reveals that the herein newly described Populus erratica Sachse, nom. nov. was previously treated under a variety of names. Due to its stratigraphical range from the late Oligocene to early Miocene, it might be a useful tool for age determinations in the terrestrial record. So far it is known only from warm-temperate floodplain forests in Central Europe – possibly even restricted to the alpine area. The taxonomic relationships to some morphologically similar species from other localities cannot be entirely clarified here.
Potential methane production and oxidation along the soil chronosequence of the Rotmoos glacier forefield
Authors: Prem Eva Maria , Praeg Nadine , Hofmann Katrin , Wagner Andreas Otto , Illmer Paul
Published: June 2019

Five differently developed soils aged 6, 35, 80, 150, and >5000 years with the same bedrock and the same (current) climate conditions were chosen to assess abiotic and enzymatic properties as well as methanogenic and methanotrophic activities. Most abiotic properties (dry weight, pH, soil organic matter, and ammonium content), enzyme activities (dehydrogenase [DH] activity, ammonification [AM] rate, dimethylsulfoxide reduction), and potential methane oxidation (PoMO) per gram of dry weight (DW) increased with soil age. In contrast, potential methane production (PoMP) as well as the nitrate content per gram of DW and most enzymatic properties per gram of soil organic matter (SOM) did not increase with soil age but reached its maximum in the middle-aged soils (80–150 years). Our results show that (i) microbial activity does not consequently increase with SOM content/soil age; (ii) methane production can be measured in undeveloped soils, whereas methane oxidation is more restricted to fully developed soils; and (iii) certain soil modifications (change in water content, ammonium addition) could influence potential methane production/oxidation. When considering the concurrent release of raw soil because of the melting of perpetual ice, these data could help to better understand and assess the consequences of global change.
Compared impact of compost and digestate on priming effect and hydrophobicity of soils depending on textural composition
Authors: Voelkner Amrei , Diercks Charlotte , Horn Rainer
Published: June 2019

Digestates and compost are used as valuable fertilizers in agriculture because of their benefits for plant nutrition and carbon sequestration potential. These amendments are also suspected to interfere negatively with the soil. To compare their relevance for priming effect and hydrophobicity of soils, two amounts of digestate or compost, respectively, were mixed with a homogenized cambic Luvisol and a Podzol. The basal respiration rate (BAS), the repellency index (RI) and organic carbon content (Corg) of pre-dried mixtures were investigated. The podsolic mixture showed quantitative reduction of Corg and increased BAS (this effect was not statistically significant) due to priming effect through microbial stimulation. As a result of enhanced organic substance (OS) protection in the cambic Luvisol mixture, constant amounts of Corg and declined BAS could be detected. The wettability was reduced in both soils: either directly by the supply of amphiphilic components or indirectly by increased incorporation of microbial exudates. This reduction was not statistically significant. Higher contents of available organic compounds in digestates and higher amounts of hydrophobic humic acids in the compost could be assumed to be decisive for generation of hydrophobicity. Also the soil texture controlled the microbial decomposition by higher incorporation of OS in finer pores and contributed to the protection against microbial decay.
ISAR Imaging of a Rotating Asteroid Irradiated by Pulsar’s Electromagnetic Emission
Authors: Lazarov Andon D.
Published: June 2019

The aim of the present study is imaging of moving objects, asteroids illuminated by continuous coherent wideband pulsar’s signals. As pulsars are located on more than thousands of light years from Earth, objects crossing pulsars’ emission beams are considered as second sources of electromagnetic waves, carrying object’s shape and velocity information that can be extracted by application pulsar emission-based inverse aperture synthesis. Inverse Synthetic Aperture Radar (ISAR) scenario, geometry and kinematics are analytically described. Models of pulsar signals and ISAR signals secondary emitted by asteroids are developed. White Gaussian noise of high level is added to the deterministic reemitted signal in order to approach the real signal scenario. Two-Dimensional (2D) Fourier transform for image extraction is applied. Special iterative noise removing procedure is suggested for asteroid’s image enhancement. To verify mathematical model and imaging algorithms numerical experiments are carried out.
An Approach to Evaluation of Clinically Healthy People by Preventive Cardio Control
Authors: Manukova Aneliya , Marinov Matey , Grozeva Maya
Published: June 2019

This article presents the main algorithms and the methodology for the development of the evaluation criteria and the results of the work of the program environment developed for evaluation and analysis of the electrocardiographic signals in the preventive control of clinically healthy people after emotional or physical stress for the purpose of diagnosing of current disorders in the cardiac activity. The presented structure combines a new approach to building an electronic system for assessing individual medical information from the real life of healthy people and a specific method for analyzing the results. The purpose of preventive control is to preserve human health through early and timely assessment of its current health status.
Impact of River Bank Erosion on Mental Health and Coping Capacity in Bangladesh
Authors: SarzamArobi  , Naher Jamiun , Soron Tanjir Rashid
Published: June 2019

Objectives

Riverbank erosion is a regular phenomenon that displaces millions of people every year worldwide. More than 100,000 people are displaced due to river erosion every year in Bangladesh. People have to resettle in a different place leaving behind their property and familiar environment. This transformation with economic crisis acts as a major stressor for the persons and their families. However, people may adapt different strategies to adapt this difficult situation and keep themselves healthy. They might have higher coping skills due to what they had to endure. This study aimed to find out the difference in the mental health status and coping strategies among the river bank erosion affected and non-affected people in Bangladesh

Methods

We interviewed 100 adult respondents, of whom 50 had been affected and 50 had never been affected by river erosion in Bangladesh. All the participants completed self-report sociodemographic questionnaires; their mental state was evaluated with the Bangla version of the General Health Questionnaire-12 (GHQ-12) and the coping was measured using the COPE scale.

Result

The mental health well-being score of the affected group was significantly lower than the non-affected group. However, accounting for gender, income and age, the affected group had lower mean score in coping (55.86) then the non-affected group (64.04). However, the difference was not statistically significant.

Conclusions

Riverbank erosion is a major natural disaster in Bangladesh that makes people vulnerable to mental disorder. However, it receives less attention; we hope this study will stimulate future researcher to explore mental state and coping mechanism in multiple perspectives and develop evidence-based service for them.
Measuring Trust in Medical Researchers: Adding Insights from Cognitive Interviews to Examine Agree-Disagree and Construct-Specific Survey Questions
Authors: Dykema Jennifer , Garbarski Dana , Wall Ian F. , Edwards Dorothy Farrar
Published: June 2019

While scales measuring subjective constructs historically rely on agree-disagree (AD) questions, recent research demonstrates that construct-specific (CS) questions clarify underlying response dimensions that AD questions leave implicit and CS questions often yield higher measures of data quality. Given acknowledged issues with AD questions and certain established advantages of CS items, the evidence for the superiority of CS questions is more mixed than one might expect. We build on previous investigations by using cognitive interviewing to deepen understanding of AD and CS response processing and potential sources of measurement error. We randomized 64 participants to receive an AD or CS version of a scale measuring trust in medical researchers. We examine several indicators of data quality and cognitive response processing including: reliability, concurrent validity, recency, response latencies, and indicators of response processing difficulties (e.g., uncodable answers). Overall, results indicate reliability is higher for the AD scale, neither scale is more valid, and the CS scale is more susceptible to recency effects for certain questions. Results for response latencies and behavioral indicators provide evidence that the CS questions promote deeper processing. Qualitative analysis reveals five sources of difficulties with response processing that shed light on under-examined reasons why AD and CS questions can produce different results, with CS not always yielding higher measures of data quality than AD.
Interaction between turbidity currents and a contour current – A rare example from the Ordovician of Shaanxi province, China
Authors: Li Hua , van Loon A.J. [lpar]Tom[rpar] , He Youbin
Published: June 2019

The silty top parts of graded turbidites of the Late Ordovician Pingliang Formation, which accumulated along the southern margin of the Ordos Basin (central China), have been reworked by contour currents. The reworking of the turbidites can be proven on the basis of paleocurrent directions in individual layers: the ripple-cross-bedded sandy divisions of some turbidites show transport directions consistently into the downslope direction (consistent with the direction of other gravity flows), but in the upper, silty fine-grained division they show another direction, viz. alongslope (consistent with the direction that a contour current must have taken at the same time). Both directions are roughly perpendicular to each other. Moreover, the sediment of the reworked turbidites is better sorted and has better rounded grains than the non-reworked turbidites.

Although such type of reworking is well known from modern deep-sea environments, this has rarely been found before in ancient deep-sea deposits. The reworking could take place because the upper divisions of the turbidites involved are silty and consequently relatively easily erodible, while the contour current had locally a relatively high velocity – and consequently a relatively large erosional capability – because of confinement within a relatively narrow trough.
Organizational sensory systems of Polish enterprises in the context of cooperative relationships
Authors: Chomicki Michał
Published: June 2019

The aim of this paper is to indicate the relationship between the shape of organizational sensory systems of Polish companies and beneficialness of the shape of cooperative relations between these companies with particular kinds of cooperators. The theoretical part of this article was devoted to the identification of the role of cooperative relations in the contemporary economic environment and a brief description of the concept of organizational sensory system, including its influence on cooperation between companies. The survey used the respondents’ indications of frequency of monitoring of elements of organization and its environment and the indication of the beneficialness of the shape of cooperative relationships with suppliers, customers and co-opetitors (in the framework of coopetitive relations). The chi-squared independence tests were used to demonstrate dependencies. In conclusion, it turned out that there are only two statistically significant relations and both of them pertain to relationships with customers.
Organizational development as a modern management tool for transformation of the company (case of Ukrainian energy company)
Authors: Doroshuk Hanna
Published: June 2019

The article is aimed at formation of the approaches and stages of organizational development for a large vertically integrated company, ensuring the country’s strategic security in the fi eld of energy. The methodological basis of this work is the theory of the company’s life cycle, and it is proposed to complement the mentioned theory with the theory of spiral dynamics, reflecting the evolution of the company’s values.

The approaches to organizational development are analysed and organizational development is defined. The possibility and necessity of management of organizational development are substantiated. As a result of the study, there were described the features of the organizational development of large energy company, and this is for the first time. The analysis of publications and world experience in the development of energy companies allowed proposing four basic stages of organizational development: team building and life cycle dynamics, value management and implementation tools.

There is offered the use of organizational development as an instrument of management, which enables to achieve not only company development goals, but also to manage its values, achieve maximum employee involvement in development, and to shift from the management of the company to team work. Further research in this area it is advisable to carry out in detail the stage of organizational development and description of each stage’s tools.
The sources of competitive advantage from the perspective of project management – results of empirical studies
Authors: Dolata Magdalena
Published: June 2019

The aim of the paper is entering the discussion concerning the sources of competitive advantage in project management in basic local government units in Poland. The focus of the paper is placed on the selected elements of the sources of competitive advantage in basic local government units in Poland, namely tasks implemented in projects. The paper consists of two main parts. In the first part of the paper, a starting point was the presentation of the essence of competitiveness and competitive advantage in the process of project management from the perspective of local government units in Poland. In the second one, the results of the research proceedings concerning the importance of tasks implemented in projects in projects in basic local government units in Poland were discussed. The considerations presented in the paper refer to the results of the research proceedings, which took place in two stages. The first stage of the studies was conducted in 2013 and it concerned the years 2010-2012, the second stage – in 2018, and it concerned the years 2016-2018.
Relational styles for solving difficult situations in an employee team
Authors: Ronginska Tatiana , Doliński Artur
Published: June 2019

The article proposes the inclusion of relational styles of managers in difficult situations occurring in an employee team. Four types of relational styles have been distinguished: partner, handler, buddy and coach. The research covered 261 middle and senior managers of one of large corporations in Poland. The research was carried out for two years during the training contract. The article presents the results of relational style research at the training stage, which allowed to diagnose the relational style of the surveyed managers.
A literature review on multimodality molecular imaging nanoprobes for cancer detection
Authors: Shahbazi-Gahrouei Daryoush , Moradi Khaniabadi Pegah , Shahbazi-Gahrouei Saghar , Khorasani Amir , Mahmoudi Farshid
Published: June 2019

Molecular imaging techniques using nanoparticles have significant potential to be widely used for the detection of various types of cancers. Nowadays, there has been an increased focus on developing novel nanoprobes as molecular imaging contrast enhancement agents in nanobiomedicine. The purpose of this review article is to summarize the use of a variety of nanoprobes and their current achievements in accurate cancer imaging and effective treatment. Nanoprobes are rapidly becoming potential tools for cancer diagnosis by using novel molecular imaging modalities such as Ultrasound (US) imaging, Computerized Tomography (CT), Single Photon Emission Tomography (SPECT) and Positron Emission Tomography (PET), Magnetic Resonance Imaging (MRI), and Optical Imaging. These imaging modalities may facilitate earlier and more accurate diagnosis and staging the most of cancers.
Study the Anti-MUC1 antibody-based iron oxide nanoparticles on three-dimension spheroid and breast cancer (MCF-7) cell imaging
Authors: Khaniabadi Pegah Moradi , Shahbazi-Gahrouei Daryoush , Majid Amin Malik Shah Abdul , Khaniabadi Bita Moradi
Published: June 2019

Non-invasive methods for breast cancer detection in early stages may help to increase the survival rate of patients. This study aimed to evaluate the application of Anti-MUC1 antibody-based iron oxide nanoparticle (SPIONs-C595) which was assessed in vivo as a molecular imaging probe for breast cancer (MCF-7) detection using MRI. Nine groups of female NRC NU/Nu mice (each group of 3), 6 to 8 weeks old were used and MCF-7 cells were injected subcutaneously into both flanks of nude mice. After two weeks the mice received an intravenous injection of different concentrations of SPIONs-C595. The uptake ability of SPIONs-C595 on three-dimension (3D) macrostructure is exploited a modified hanging drop method using Prussian blue for MCF-7 cells. The iron content was measured in liver, kidney, spleen, and tumor. The MR imaging features and biodistribution of nanoprobe was also investigated. The MR images obtained from digested tumor after nanoprobe administration in different time-period revealed that enhancement of T1 and T2 relaxation time. Moreover, the storage stability test was shown great application and no sedimentation of nanoparticles within two months storage at 4°C. Additionally, great validation of SPIONs-C595 on the 3D spheroid of MCF-7 was observed. The biodistribution analysis showed that iron content of the spleen was more than the other studied organs. These results highlighted the feasibility of an in-vivo model for detection of breast cancer MUC1 expression. Current researches are ongoing to further enhancement of relaxation times for classification of MUC1 status using clinical specimens.
A Monte Carlo study on the radio-sensitization effect of gold nanoparticles in brachytherapy of prostate by 103Pd seeds
Authors: Jangjoo Amir Ghasemi , Ghiasi Hosein , Mesbahi Asghar
Published: June 2019

103Pd seed is being used for prostate brachytherapy. Additionally, the dose enhancement effect of gold nanoparticles (GNP) has been reported in previous studies. The aim of this study was to characterize the dosimetric effect of gold nanoparticles in brachytherapy with a 103Pd source. Two brachytherapy seeds including 103 Pd source was simulated using MCNPX Monte Carlo code. The seeds’ models were validated by comparing the MC with reported results. Then, GNPs (10 nm in diameter) with a concentration of 7mg Au/g were simulated uniformly inside the prostate of a humanoid computational phantom. Additionally, the dose enhancement factor (DEF) of nanoparticles was calculated for both modeled brachytherapy seeds. A good agreement was found between the MC calculated and the reported dosimetric parameters. For both seeds, an average DEF of 23% was obtained in tumor volume for prostate brachytherapy. The application of GNPs in conjunction with 103Pd seed in brachytherapy can enhance the delivered dose to the tumor and consequently leads to better treatment outcome.
The effect of SSD, Field size, Energy and Detector type for Relative Output Factor measurement in small photon beams as compared with Monte Carlo simulation
Authors: Setilo Itumeleng , Oderinde Oluwaseyi Michael , Plessis Freek Cp du
Published: June 2019

Introduction: Small fields photon dosimetry is associated with many problems. Using the right detector for measurement plays a fundamental role. This study investigated the measurement of relative output for small photon fields with different detectors. It was investigated for three-photon beam energies at SSDs of 90, 95, 100 and 110 cm. As a benchmark, the Monte Carlo simulation was done to calculate the relative output of these small photon beams for the dose in water.

Materials and Methods: 6, 10 and 15 MV beams were delivered from a Synergy LINAC equipped with an Agility 160 multileaf collimator (MLC). A CC01 ion chamber, EFD-3G diode, PTW60019 microdiamond, EBT2 radiochromic film, and EDR2 radiographic film were used to measure the relative output of the linac. Measurements were taken in water for the CC01 ion chamber, EFD-3G diode, and the PTW60019. Films were measured in water equivalent RW3 phantom slabs. Measurements were made for 1 × 1, 2 × 2, 3 × 3, 4 × 4, 5 × 5 and a reference field of 10 × 10 cm2. Field sizes were defined at 100cm SSD. Relative output factors were also compared with Monte Carlo (MC) simulation of the LINAC and a water phantom model. The influence of voxel size was also investigated for relative output measurement. Results and Discussion: The relative output factor (ROF) increased with energy for all fields large enough to have lateral electronic equilibrium (LEE). This relation broke down as the field sizes decreased due to the onset of lateral electronic disequilibrium (LED). The high-density detector, PTW60019 gave the highest ROF for the different energies, with the less dense CC01 giving the lowest ROFs.

Conclusion: These are results compared to MC simulation, higher density detectors give higher ROF values. Relative to water, the ROF measured with the air-chamber remained virtually unchanged. The ROFs, as measured in this study showed little variation due to increased SSDs. The effect of voxel size for the Monte Carlo calculations in water does not lead to significant ROF variation over the small fields studied.
Feasibility study of conformal forward planned simultaneous integrated boost technique comparable to IMRT and VMAT in pelvic irradiation for locally advanced cervical cancer
Authors: Johnjothi Sam Deva Kumar , Ranganathan Arulpandiyan , Jayapaul Vasanth Christopher , Santosham Rithesh , Rajasekaran Dhanabalan , Nagarajan Vivekanandan , Ganesharaja Selvaluxmy
Published: June 2019

Aim: To check the feasibility of simultaneous integrated boost (SIB) using a forward planned field in field (FIF) conformal technique for the treatment of carcinoma of the cervix IIIB and compare it dosimetrically with other advanced inverse planning techniques.

Methods: In our study 33 patients of carcinoma of the cervix IIIB were planned for SIB using conformal FIF technique and they were compared with retrospectively planned IMRT and VMAT techniques. SIB using conformal FIF was planned by two different methods.

Results: The results of our study indicate that forward planned Conformal SIB techniques are comparable with inverse planned techniques dosimetrically, in terms of conformity Index, Homogeneity Index, Maximum dose, etc. The ability of FIF SIB plans to produce dose contrast in differential dose accumulation was compared and analyzed and the results were encouraging. To treat an advanced/bulky disease like Carcinoma of the Cervix IIIB in centers with large patient load, utilizing advanced techniques such as IMRT and VMAT is both technically and practically difficult. Despite VMAT’s shorter delivery time, the procedures involved are time-consuming.

Conclusion: Hence forward planned SIB techniques may be used to achieve similar dosimetric effects of IMRT and VMAT techniques without much compromise in plan quality and patient throughput for treating bulky carcinoma of the cervix IIIB cases. However, the clinical results need to be carefully compared and evaluated and reported.
Prevalence of Rapid Weight Loss Practices and Their Profiles Among Non-Elite Combat Athletes in Kuching, East Malaysia
Authors: Cheah Whye Lian , Bo Myat Su , Kana Winnie Anak , Tourisz Nur Irdina Binti Mohd , Ishak Mohamad Arif Hadzimi Bin , Yogeswaran Mahanagaraani
Published: June 2019

Introduction.
Rapid Weight Loss (RWL) is a common practice in combat sports where weight is classified to ensure equitable competition in terms of strength and agility. This study aimed to investigate the profiles of non-elite combat athletes and their RWL practices.

Material and methods
. This research was a cross-sectional study conducted in Kuching, Sarawak. Data were collected using a validated self-administered dual-language questionnaire.

Results.
A total of 65 respondents participated in the study; two-thirds were male, and the majority were taekwondo athletes. About 66% of the respondents reported to have practised rapid weight loss, with average weight loss of 3.4 kg (SD = 1.90) and highest weight loss of 4.9 kg (SD = 3.16). The most common RWL methods used were exercising more (69.8%), gradual dieting (51.1%), and training in heated rooms (20.8%). Physical trainers and training colleagues were rated as persons having the most influence on the use of RWL by the respondents. The perceived adverse effects which were mentioned the most frequently by the respondents were fatigue (69.2%), decreased vigour (50.8%), and muscle cramps (46.2%). As for the type of combat sport practised, muay thai and jiu jitsu had the highest number of respondents who used RWL. There were significant differences in RWL practices depending on the influences of training colleagues, physicians/doctors, physical trainers, parents, dieticians, and former athletes as well as perceived adverse effects of RWL.

Conclusions
. The findings of the current study were observed to be similar to those of research involving elite combat sport athletes where the prevalence of RWL was reasonably high, with similar characteristics. A proper regulatory programme should be put in place to assist both the athletes and their coaches/trainers in implementing proper weight control.
Sensory Evaluation of Liver/Meat Pâté Made from Fresh or Frozen Eland Meat and Beef
Authors: Kolbábek P. , Maxová P. , Kouřimská L. , Lukešová D. , Kotrba R.
Published: June 2019

Small animal producers in Europe can financially benefit if they sell not only carcasses or dissected cuts, but also processed meat and edible offal in value added products such as traditional and popular pâté. In particular, when introducing a new exotic species like eland (Taurotragus oryx) to the market, the sale of low valued cuts with higher collagen content is problematic. Therefore, we aimed to evaluate the sensory traits of several pâtés made from liver and less valuable fresh or frozen meat cuts (neck, brisket and plate) of eland and cattle. Four batches of pâté made from fresh and frozen material (45 and 90 days) were tested by 35 panellists using sensory profiling method with 14 descriptors. Two pâté batches consisted of chicken liver and beef or eland meat. Another two were made from eland or beef liver together with eland meat. Pâté made from fresh material, including chicken or eland or beef liver, together with eland meat or beef showed the main differences in textural characteristics such as friability, overall texture being better scored for pâté which includes chicken liver. Chicken liver also resulted in a higher intensity of colour. Freezing of material (meat and liver) before processing into pâté resulted in worse scoring of the final product. Chicken liver batches scored better in sensory traits of overall appearance, pleasantness of taste, colour and intensity of colour, colour hue and textural friability, overall texture and of pleasantness of consistency. Pâté made from chicken liver from frozen material also had lower off-flavour. This pilot study showed that pâté from fresh eland meat and chicken liver scored the best in most of the sensory traits. Freezing and storing meat and liver before processing resulted in worse scores, especially in olfactory, visual and textural traits. The use of chicken liver instead of eland or beef liver to process pâté improves sensory traits.
Effect of Genotype on Ileal and Caecal Microbiota in Pasture-Reared Dominant Cockerels
Authors: Čermák L. , Vlčková J. , Skřivanová E. , Laloučková K. , Englmaierová M.
Published: June 2019

Outdoor access is an important part of organic and free-range poultry production, yet limited information exists on the effect of various housing and production systems on the growth performance and colonization of food-borne pathogens. Therefore, the primary purpose of the current study was to evaluate the influence of different housing systems (particularly fixed versus small, portable houses, with and without outdoor access to pasture) and different broiler genotypes on the gastrointestinal bacteria in broilers. The fundamental factor studied was the presence of any quantitative changes in common gastrointestinal microbiota, including pathogenic genera such as Campylobacter sp. and Salmonella sp. The results showed differences in intestinal microbiota and confirmed lowered counts of caecal coliforms in pasture-reared broilers.
Negative Transfer in Lithuanian Students’ Writing in English
Authors: Daukšaitė Aurelija
Published: June 2019

This research intends to find out whether Lithuanians studying English as a foreign language make certain mistakes because of the influence of their native language. It focuses on negative transfer in writing in English and is qualitative rather than quantitative. The article discusses the errors and illustrates them with examples that come from a corpus for which the data was obtained from 34 Moodle forum posts written by English B2 students, native speakers of Lithuanian who were in year one or year two of their studies in various study programmes but also studied English at Vytautas Magnus University as an obligatory subject. The students participated in this forum in October 2018 and reflected on the week of presentations they had recently had: they were asked to write what they liked or did not like in the presentations their colleagues had given in class, what went well and what did not, what they should improve in the future, etc. This study identified the types of errors (based on Camilleri, 2004) that occurred most frequently and their source (based on Camilleri, 2004; Brogan & Son, 2015). Most frequently the students made errors in the cases where there was a specific grammatical category in English, but it was non-existent in Lithuanian, while sometimes the source of errors was literal translation from the native language. The error analysis shows that in the English classroom specific attention should be given to the verb forms “is” and “are”, “was” and “were”, “has” and “have”, articles, collocations, tense agreement, quantifiers, the sentence structure of the English language and the importance of word meanings.
Barriers to and Strategies for Sustainable Relationships in Multilingual Campuses
Authors: Mambetaliev Askar
Published: June 2019

The article presents the dimensions of communication in multiethnic and multilingual education settings, the main barriers to sustainable relationships between students of different backgrounds and strategies to overcome those barriers. The main research question of the study is: What are the main barriers in sustainable relationships between students with different ethnic and linguistic backgrounds? A subsequent question is: How to overcome those barriers? Hence, the main goal of the article is to identify and address the main problems that undermine mutual understanding and collaborative learning among students. The method of the study is a literature review of the most significant studies and authors in the field. The goal is to present an analysis of their insights into the main problems of relationships between students on international campuses. The article is useful for campus leaders, students and mentors.
POSISI DESA SERANGAN BERDASARKAN ANALISIS TOURISM AREA LIFE CYCLE
Authors: Suryaningsih Ida Ayu Anggreni , Suryawan Ida Bagus
Published: June 2019

Abstract In the development of a tourist area, especially the development of tourism will generally follow the pattern of grooves or tourism area life cycle is known as the Tourism Area Life Cycle (TALC). This paper aims to find a position that tourism in Serangan Village, so it can later be known by both programs suitable for the development of the area. The needs of the data used to meet, namely, observation, literature review and interviews with some of the residents and community leaders in the village attack. The collected data will be described later analyzed by descriptive. Observations show that the position of the Serangan Village in Tourism Area Life Cycle analysis is at a stage 2 or the stage engagement (involvement). In this phase, the increase in the number of tourist arrivals in the Serangan village has increased every year and the local people who were there already started to supply the needs of tourists as a cafe or restaurant and homestay but still on a limited scale. Local people have started actively promoting in several blogs and web is also working with several travel agents. The creation of a forum for the community to develop into a more concerted Serangan village to be planned future namely the formation of a group of fishermen who called Karya Segara. The group is very active fishing village of attacks and protecting the environment are very enthusiastic about the preservation of underwater attack. Starting from the initiative group of fishermen began to attack this village known and increasingly shows its uniqueness in terms of environmental conservation. This it can be concluded that the position of the Serangan Village in Tourism Area Life Cycle analysis is in phase engagement (involvement) were associated with the facts on the ground.