bluuebunny/crossref_metadata_2025 huggingface dataset:
POLA TRANSAKSI PADA COMMODITY EXCHANGE : Perspektif Hukum Islam
Authors: Efrinaldi Efrinaldi
Published: December 2017

Transactions on commodity exchange as futures trading are seen from the contract cycles as a pure trade activity, reduce the risk of profit from buying and selling, as a result of price fluctuations on trading commodities. Price fluctuations can be predicted and transactions begin with analysis, while risk can be protected.

The type of transaction on physical goods and the spot market, in the perspective of Islamic economic law, can be tolerated. Certain types of trade (al-tijarah) have been arranged in syara ', because indeed the forms of transactions in such trades have been tolerated in the time of the Prophet. Spot markets, such as transactions of agricultural products, livestock, minerals, handicrafts, industry, and so forth. While transactions service that are non-physical, eg rent (al-ujrah) and wage-hire (al-ijarah).

The aim of trade is essentially objects of economic value with the availability of goods in aqad assemblies (at the time of the transaction). In the Islamic review, this also applies to items that are not available or without presenting the goods at the time of the transaction, provides the ordered item is concrete of its nature. This is non-existent form of trade (such as al-salam), in Islamic law studies, depends on seller's effective control and ability to deliver. There is a protection against the value of goods transacted from probabilities that are inconsistent with the properties specified in the aqad assemblies, protection against the interests of consumer from loss (cut loss) and no disappointment in the future. In futures trading, it is known as the term of hedging
Preferensi Strategi Pemasaran Bank Syari’ah Menanggapi Perilaku Konsumsi Masyarakat Saat Musim Panen
Authors: Anjaswara Rendra , Hardivizon H
Published: December 2017

Consumption behavior that shown by the community during the harvest season has not aroused awareness of sharia banks to implement special marketing strategies in response to the phenomenon. This research is a field research with qualitative approach. The location of this research is in DusunSawah,North Curup District, RejangLebongRegency with the consideration of the number of people who work as farmers and the extent of agricultural land and plantations. The results showed that the consumption behavior of farmers in DusunSawah is consumptive during the harvest season. Consumptive behavior is influenced by three dominant factors, namely cultural factors, social factors, and personal factors. Therefore, the preference of marketing strategies that can be applied by sharia banks in response to consumptive behavior of farmer society ofDusun Sawah in harvest season is concentrated marketing strategy with the concept of event marketing and coffee break marketing.
Penerapan Pembelajaran Kooperatif Tipe Jigsaw Dalam Upaya Meningkatkan Pengelolaan Pembelajaran Dan Aktivitas Siswa Kelas V MIS Guppi NO.13 Tasik Malaya Curup Utara
Authors: Syaripah Syaripah
Published: December 2017

Penelitian ini berfokus pada rendahnya hasil pembelajaran matematika dalam aspek aktivitas siswa dalam belajar matematika yang rendah serta pembelajaran yang diterapkan selama ini belum tepat. Oleh karena itu diperlukan suatu upaya yang memperbaiki proses pembelajaran. Salah satu upaya menerapkan pembelajaran kooperatif tipe jigsaw. Penelitian ini termasuk Penilaian Tindakan Kelas yang dilakukan pada MIS Guppi No. 13 Tasik Malaya dengan subjek penelitian adalah kelas V yang berjumlah 21 siswa. Hasil penelitian menunjukkan pada siklus I belum menunjukkan hasil yang optimal oleh karena itu dilakukan siklus II. Pada siklus II menunjukkan adanya peningkatan yaitu kadar aktivitas aktif siswa pada siklus I terdapat 3 (tiga) meningkat menjadi 4 (empat) dari 7 kategori aktivitas aktif siswa dan kemampuan guru dalam mengelola pembelajaran pada tindakan siklus I “cukup baik” (nilai 3,57) menjadi “baik” (nilai 4,10) pada siklus II. Simpulan penelitian adalah penerapan pembelajaran kooperatif tipe jigsaw dapat meningkatkan aktivitas aktif siswa dan kemampuan guru dalam mengelola pembelajaran.

Kata kunci : Pembelajaran Kooperatif Tipe Jigsaw, Aktivitas Siswa dan Kemampuan Mengelola Pembelajan
Model Pembelajaran Berbasis Discovery- Inkuiri dan Kontribusinya Terhadap Penguatan Kualitas Pembelajaran di Sekolah Dasar
Authors: Sirait Maruslin
Published: December 2017

A convensional teaching models and monotonous that often happen in teaching process needs to behave seriously by the stakeholder that there are in makro and mikro levels, especially for the teacher that in touch directly in teaching process. teachers need to realize that basically the students have learning variation that we cant make it in the same way. Learning models that should be understood by the teachers in doing learning to create a masterpiece learning process that can change learning situation from passive become active and reactive for the students.
Peran Guru Dalam Menanamkan Nilai Kejujuran Pada Lembaga Pendidikan
Authors: Amin Muhammad
Published: December 2017

Saat ini dunia pendidikan mendapat sorotan yang tajam dari berbagai kalangan, tidak lain karena banyaknya generasi muda, khususnya pelajar melakukan tindakan-tindakan negatif, seperti tawuran, perkelahian, pencurian, dan tindakan kekerasan lainnya. Kondisi ini menunjukkan bahwa ada sesuatu yang keliru dalam sistem pendidikan nasional, terutama dalam hal pendidikan karakter. Oleh karena itu, pendidikan karakter terus didengungkan agar selalu menjadi perhatian yang serius dan diimplementasikan dalam lembaga pendidikan (sekolah). Salah satu unsur terpenting dalam pendidikan karakter adalah kejujuran. Sesungguhnya orang yang memiliki sifat jujur akan dihormati dan dikagumi oleh orang lain, bahkan Allah SWT menempatkan orang yang jujur pada golongan yang dicintai oleh Allah SWT. Sifat jujur ini merupakan salah satu sifat yang ada pada diri Nabi dan Rasul. Dewasa ini kejujuran merupakan sesuatu yang langka. Berbagai kasus terjadi, seperti kebiasaan mencontek di kalangan siswa, korupsi di berbagai level, penipuan, penggelapan uang, kasus kriminal lainnya, mulai dari kalangan pelajar sampai kalangan pejabat tinggi, dikarenakan faktor ketidakjujuran. Untuk itu, guru sebagai sentral dalam pendidikan di sekolah, memiliki peran yang penting dalam menanamkan nilai kejujuran pada anak. Beberapa hal yang dapat diterapkan oleh guru dalam penanaman nilai kejujuran diantaranya; melakukan pengajaran secara terus-menerus dan terintegrasi antar setiap komponen sekolah, menjadikan dirinya sebagai suri teladan bagi anak didiknya, membiasakan peserta didik untuk berperilaku jujur, melakukan refleksi diri, dan memberikan punishment kepada anak yang berperilaku tidak jujur

Kata Kunci : Peran Guru, Kejujuran, Lembaga Pendidikan
Peningkatan Mutu Pendidikan Agama Islam Berbasis Kontekstual
Authors: Kusen Kusen
Published: December 2017

Pendidikan Agama Islam (PAI) sebagai salah satu mata pelajaran di sekolah mempunyai peranan yang strategis dalam pembentukan akhlak dan pribadi siswa. Proses pembelajaran yang dilakukan oleh guru belum optimal berdampak positif dalam pembentukan akhlakul karima pada diri siswa, terlihat akhlak siswa yang masih mencerminkan akhlak yang tercela, misalnya siswa sering ribut dikelas ketika guru menjelaskan pelajaran, bolos pada jam sekolah, tawuran dan sebagainya. Untuk menjawab persoalan-persoalan tersebut perlu diterapkan suatu cara alternatif mempelajari Pendidikan Agama Islam yang kondusif dengan suasana yang cenderung rekreatif sehingga memotivasi siswa untuk mengembangkan potensi kreativitasnya. Salah satu alternatif yang bisa digunakan adalah dengan penerapan pembelajaran kontekstual sebagai bahan pertimbangan bagi beberapa pihak, antara lain bagi guru, pembelajaran kontekstual ketika diterapkan pada bidang studi Pendidikan Agama Islam.

Kata Kunci: Mutu, Pendidikan Agama Islam dan pembelajaran Kontekstual
ALOKASI OPTIMUM DAN WILAYAH PENGEMBANGAN PERIKANAN BERBASIS ALAT TANGKAP POTENSIAL DI TELUK JAKARTA
Authors: Radarwati Siti , Baskoro Mulyono S. , Monintja Daniel R. , Purbayanto A.
Published: December 2017

Jakarta Bay and its neighbouring waters of Seribu Islands are categorized as fullly exploited water areas which theirs coastal areas accomodate multifunction services. Therefore, it needs precautionary approach to manage fisheries activity in that locations. The objectives of this study are to determine optimum allocation of fishing gears and fisheries development areas based on potential fishing gears in Jakarta Bay. The methods used in this study are Linear Goal Programming (LGP) and Locations Quotient (LQ). The result revealed that the potential fishing gears to be developed were pelagic danish seine, drift gillnet, boat lift net, set bottom long line, portable trap and muroami which have the optimum allocation for each fishing gear; 7 units, 98 units, 23 units, 18 units, 8547 units, and 798 units. The potential fishing gears for pelagic danish seine could be developed in Penjaringan and North Seribu Island Districts; drift gillnet could be developed in Cilincing District; boat lift net could be developed in Penjaringan District; set bottom long line could be developed in Penjaringan District; portable trap could be developed in Cilincing and South Seribu Island Districts while muroami could be developed in Penjaringan and South Seribu Island Districts.
POTENSI WISATA BAHARI PULAU-PULAU KECIL DI KAWASAN KAPOPOSANG KABUPATEN PANGKEP
Authors: Samudra Krishna , Baskoro Mulyono S. , Wisudo Sugeng H. , Iskandar Budhi H.
Published: December 2017

Kapoposang area is located in Pangkep Regency consist of six small islands and consist of high marine and fisheries resources, especially the white sandy beaches and coral reefs within its ecosystem. This is an important factor for further development of marine tourism based on conser-vation. Identification of marine tourism resources is the first step in development planning process. Focus Group Discussion (FGD) and survei method was applied in this research. The result show that this area is a potential area to be developed as marine tourism area based on conservation consideration.
KONSUMSI OKSIGEN BENIH IKAN KERAPU BEBEK (Cromileptes altivelis) UKURAN PANJANG 5-7 CM
Authors: Novita Yopi , Iskandar Budhi Hascaryo , Murdiyanto Bambang , Wiryawan Budy , Hariyanto Hariyanto
Published: December 2017

Disolved oxygen plays an important role for fish living in its life environment. Information on the ammount of oxygen consumption of a fish in certain volume of water is needed in order to give balancing between the ammount of disolved oxygen and fish in it. The objective of this research is obtaining oxygen consumption level of a juvenile of humpback grouper (Cromileptes altivelis) of 5-7 cm body length. Oxygen consumption of fish was measured using a tube that equiped with DO tool (dissolved oxygent, DO), and the tube was filled by sea water. Measurement of oxygen con-sumption of juvenil was done by measuring the concentration of dissolved oxygen from sea water in the respirometer tube, began when fish had entered into the respirometer tube up to two hours observation. The result showed that oxygen consumption rate of a juvenile of humpback grouper (Cromileptes altivelis) of 5-7 cm length, is ranging between 0.816 and 1.734 mg/hour.
ANALISIS INDRA PENGLIHATAN IKAN KERAPU MACAN (Epinephelus fuscoguttatus) DAN HUBUNGANNYA DALAM MERESPONS UMPAN
Authors: Riyanto M , Purbayanto Ari , Natsir D S.S.
Published: December 2017

The visual organ in fish has an important role in ensuring its survival. Fish can respond to bait or food with its visual organ. The objectives of this research are to analyse the visual performance of grouper (cone cell morphology, the visual axis, and visual acuity) and to analyse the relation between visual senses with fish behavior response to the bait. This research was conducted in the laboratory by means of the determination of fish retina histology method and behavior of fish. The morphology retina of grouper consists of a single cone and double cone which form a mosaic structure, the visual axis was identified at upper-fore with the angle of 26.8o.The visual acuity of grouper was low in index values with ranged from 0.06 to 0.07 for fish with a total length of 200 to 300 mm, the maximum sighting distance to the bait with the diameter of 20 mm size ranged from 3.93 to 4.74 m, the bait with 25 mm diameter size range from 4.91 to 5.92 and bait with a diameter of 30 mm size ranged from 5.89 to 7.11 m. The frequency of fish closed the bait distance of 30 cm was 45.83%, 25 cm was 33.33% and 20 cm was 20.83%, respectively.
TINJAUAN HUKUM DAN KEBIJAKAN KAWASAN KONSERVASI LAUT (KKL) MUKIM IE MEULEE, KOTA SABANG: Suatu Implementasi Pengelolaan Perikanan Tangkap di Pulau Kecil
Authors: Yulianto Irfan , Wiryawan Budy , Mukminin A
Published: December 2017

The coastal area of Weh Island is divided into sub-districts (lhok) which are managed by traditional leader known as Panglima Laot. The Panglima Laot has the authority to regulate customary laws that aimed to bring social harmony and resolve conflicts concerning the marine resource use. In Anoi Itam and Ie Meulee of the east coast of Weh Island, the communities have high awareness toward the sustainable of the natural resources use, and this has led to the implementation of gear restrictions and no fishing zones regulations as part of their customary laws. These regulations have generated conflict with the other custom community, because the other custom community claimed that these existing customary regulations do not have legal base regulations. Gap analysis and analytical hierarchy process was used to analyze and describe the regulation that can be used as their optional regulation base. The result indicated that the Weh Island custom community had chosen a marine protected area that managed by community through Panglima Laot adopting regulations that recognised by local government. In the process of implementation, the determination area is a key priority (36.92%) followed by the establishment of management institutions (23.92%), financing (21.19%) and surveillance (17.94%).
SUBSTANTIATION OF THE STUDY ON PREDICTION OF SURGICAL DENTAL TREATMENT FOR WOMEN IN THE PERIOD OF MENSTRUATION ON THE BASIS OF THE FREQUENCY OF THIS RISK FACTOR DETECTING BASED ON ANAMNESIS
Authors: Sudakova S. E. , Pohodenko-Chudakova I. O.
Published: December 2017

SUBSTANTIATION OF THE STUDY ON PREDICTION OF SURGICAL DENTAL TREATMENT FOR WOMEN IN THE PERIOD OF MENSTRUATION ON THE BASIS OF THE FREQUENCY OF THIS RISK FACTOR DETECTING BASED ON ANAMNESIS
CERULOPLASMIN IN EXPERIMENTAL OVARIAN TORSION/DETORSION
Authors: Lazăr C.
Published: December 2017

CERULOPLASMIN IN EXPERIMENTAL OVARIAN TORSION/DETORSION
ATOM-ABSORTIVE SPECTROMETRY FOR DETERMINING OF THE ELEMENTAL CONTENT OF THE GLYCYRRHIZA GLABRA ROOTS
Authors: Kasimova D.B. , Abdukhalikova N.U. , Gaibnazarova D.T.
Published: December 2017

ATOM-ABSORTIVE SPECTROMETRY FOR DETERMINING OF THE ELEMENTAL CONTENT OF THE GLYCYRRHIZA GLABRA ROOTS
Analisis Elemen Visual Pada Promosi Busana Muslimah di Instagram (Studi Kasus Merek Hijab Juniper Lane, Zaha, dan Zysku Xena di Bandung)
Authors: Fetrianggi Ramadita , Mutiaz Intan Rizky , Widiawati Dian
Published: December 2017

Analysis of Visual Elements on Muslimah Clothing Promotion in Instagram (Case Study on Brands of Hijab Juniper Lane, Zaha, and Zysku Xena in Bandung). Muslim clothing in the form of hijab has become popular as a religious lifestyle and identity. The popularity of hijab is due to the promotion of marketing through instagram displaying muslim fashion clothing that is designed very interesting, so that consumers become interested and marketing becomes increasing. This study aims to examine muslim clothing photos on instagram hijab with brands of Juniper Lane, Zaha, and Zysku Xena in Bandung seen from the visual elements of photography. The research method used case study with descriptive approach through visual analysis. The research subjects are instagram photos on Juniper Lane hijab brand, Zaha, and Zysku Xena in Bandung. Data collection techniques were collected by observation, instagram photo documentation study, and interviews with local brand owners of hijab and consumers. Data were analyzed by visual analysis, content analysis, and qualitative analysis. The results show that muslim clothing photos on instagram with brands of hijab Juniper Lane, Zaha, and Zysku Xena in Bandung have fulfilled the visual elements of photography, so the photo design becomes attractive, the consumers become interested in them, and the marketing becomes increasing.
Can All Benign Gallbladder Diseases be Managed Laparoscopically?
Authors: Ratan Md Ezharul Haque , Alam Hasina , Karim Md Abdul
Published: December 2017

Background: Laparoscopic cholecystectomy (LC) operation is widely practiced in gallbladder diseases. However, controversy persists for LC in acute gall bladder disease, as risk of complications appears to be greater than open procedure1. This study presents the outcome of LCs performed as the first option of treatment in benign chronic as well as acute gall bladder diseases.Methods: Twelve hundred consecutive patients of gall bladder disease, both acute and chronic, underwent cholecystectomies by a single surgeon using standard four port technique. Age, sex, diabetes, prior abdominal procedures, per-operative findings, additional procedure done and complications directly related to surgical technique were evaluated.Results: The laparoscopic approach was attempted in all patients of this series. Success rate was 99.58%. Non diabetic patients presented much earlier for surgery then diabetic patients. About one third (31.4%) of the patients had acute cholecystitis and its complications and none of them required conversion. Conversion rate was seen among those with long history of gall stone and fibrosed contracted gall bladder at ultrasonography. There were three bile duct injury cases among which two were managed laparoscopically and one needed conversion. Most of the patients (94.5%) were discharged within 20 hours of surgery. There was one mortality (0.08%) in this series.Conclusion: LC has proved to be an effective and safe day case surgical procedure for benign gall bladder pathologies and their complications. It provides much benefits with low complication and conversion in experienced hands.Birdem Med J 2018; 8(1): 35-41
Primary Disseminated Intra-abdominal Hydatid Disease: A Case Report
Authors: Zaman Shahana , Rahim Muhammad Abdur , Uddin Khwaja Nazim
Published: December 2017

Hydatid disease in human is common and liver is the most common site of involvement followed by lungs. Within the abdomen, hydatid disease can disseminate to involve spleen, pancreas, mesentery, kidney, ovary, gut, supra-renal glands etc. Such disseminations are usually secondary to rupture of a cyst: spontaneous, iatrogenic or traumatic. Without such a history, primary disseminated intra-abdominal hydatidosis is rare. Here we present such a case.Birdem Med J 2018; 8(1): 75-76
Tuberculous cystitis
Authors: Mallick MS
Published: December 2017

Pulmonary tuberculosis is very common but genitourinary tuberculosis, specifically tuberculous cystitis is very rare. A 40 year old male patient came to a teaching hospital on 26 June 2016 with the complaints of fever, painful micturition, haematuria, lower abdominal pain and gradual loss of weight. The case was diagnosed as tuberculous cystitis and treated accordingly and successfully. In this report, the case condition, procedure of diagnosis and treatment are reported in details.Mediscope Vol. 4, No. 2: Jul 2017, Page 35-38
Elimination of Indian Citrus Ringspot Virus in Kinnow by Using Phytoproteins with Shoot‐tip Grafting
Authors: Bishnoi Vikas , Goyal Anshul , Verma HN
Published: December 2017

The combined beneficial effect of shoot‐tip grafting with phytotherapy of different phytoproteins obtained from roots of Boerhaavia diffusa and leaves of Clerodendrum aculeatum to eliminate Indian citrus ringspot virus (ICRSV) from Kinnow is reported. The study also reports the effect of these phytoproteins on the growth and proliferation of Kinnow explants when nodal segments from infected mother plants (confirmed by RT‐PCR) cultured in MS containing different concentrations of aqueous extracts of these individual phytoproteins. Shoot‐tips from these nodal sprouts were grafted on Citrus jambhiri under in vitro condition. Phytoproteins from C. aculeatum were found utmost effective in respect of elimination of 50% virus followed by B. diffusa (40%). In respect of promotion of growth and proliferation of nodal explants, B. diffusa was found most effective followed by C. aculeatum. The plants were considered virus‐free when they showed absence of ICRSV in both DAC‐ELISA and RT‐PCR tests.Plant Tissue Cult. & Biotech. 27(1): 1-11, 2017 (June)
Regeneration of Asparagus officinalis L. Through Embryogenic Callus
Authors: Azad Mustafa Abul Kalam , Amin Muhammad Nurul
Published: December 2017

A plant regeneration system was established from hypocotyl explants of in vitro grown seedlings of A. officinalis and in vitro proliferated shoots, respectively through somatic embryogenesis and embryogenic calli. Somatic embryogenesis was significantly influenced by the types of plant growth regulators. Embryogenic calli with somatic embryos developed well in MS supplemented with 2.0 ‐ 4.0 μM BAP and 1.0 ‐ 4.0 μM 22,4‐D, NAA or IBA. The highest frequency (95.3%) of embryogenic calli and 55.2 somatic embryos formation were obtained when the MS was amended with 4.0 μM BAP and 2.0 μM 2,4‐D. The best embryo germination occurred in 1.0 μM BAP supplemented MMS. The highest 97.2% of shoot proliferation was observed in embryogenic calli in MS medium containing 2.0 μM BAP and 1.0 μM IBA. In vitro grown shoots were rooted in MMS with 1.0 ‐ 2.0 μM IBA. Regenerants were transferred to vermicompost and successfully established under an ex vitro environment in garden soil with 80% survival rate.Plant Tissue Cult. & Biotech. 27(1): 21-31, 2017 (June)
Molecular Characterization of Tropical Strawberry Genotypes
Authors: Sweety MA , Hossain MM , Hoque MA , Hasan M , Ivy NA , Islam MN , Sarker RH , Mitra S
Published: December 2017

Genetic variability of tropical strawberry genotypes was determined through Ramdom Amplified Polymorphic DNA (RAPD) primers. Out of 14 RAPD primers six showed reproducible and polymorphic bands. The results revealed that the maximum polymorphic bands were produced by the primer OPB 12. Ten genotypes were differentiated into two clusters on the basis of Unweighted Pair Group Method With Arithmetic Averages (UPGMA). Genotypic variation based on molecular characterization indicated that genotypes belonging to two different clusters depend on their genetic component. So, selection of parents from different clusters will provide the maximum heterosis in yield.Plant Tissue Cult. & Biotech. 27(1): 33-39, 2017 (June)
Embryogenic Callus Induction and Efficient Plant Regeneration in Three Varieties of Soybean (Glycine max)
Authors: Islam Nazrul , Islam Touhidul , Hossain Md Munir , Bhattacharjee Bakul , Hossain M Monzur , Islam SM Shahinul
Published: December 2017

An efficient callus induction and plant regeneration system has been developed using three local soybean (Glycine max L.) varieties. All the varieties showed good callusing (78.30 ‐ 88.80%) from shoot tip (ST) in MS + 3.0 mg/l 2,4‐D + 1.0 mg/l BAP. Best callus induction and embryo formation were recorded in T5 for BS‐6 as 88.80 and 81.20%, respectively from ST. In case of cotyledonary node (CN) the maximum callus induction (82.40%) and embryo formation (74.20%) were recorded also in T5 for BS‐6. Highest frequency (79.40%) of plant regeneration was recorded where ST were used and cultured in MS supplemented with 2.5 mg/l BAP + 1.0 mg/l NAA as well as 76.30% from CN in BS‐6. The length of shoot was observed 5.32 and 4.62 cm, respectively from ST and CN for BS‐6 with the same medium composition. It was observed that half strength of MS + 2.0 mg/l IBA showed best rooting (9.04). Among the genotypes BS‐6 proved to be best explants than ST that exhibited better performance on callus induction and green plant regeneration for all parameters.Plant Tissue Cult. & Biotech. 27(1): 41-50, 2017 (June)
Somatic Embryogenesis and Subsequent Plant Regeneration from Zygotic Embryo Derived Callus of Rubber (Hevea brasiliensis Muell. Arg).
Authors: Rahman Md Mahbubur , Mahmood Maziah , Abdullah Norhani , Shaharuddin Noor Azmi , Parvin Waheeda
Published: December 2017

A protocol has been developed for induction, maturation and germination of the zygotic embryo derived callus of the rubber tree (Hevea brasiliensis Muell. Arg.). The influence of plant growth regulators (PGRs) including 2,4‐D, α‐NAA, picloram, GA3 and TDZ on MS and MMS were studied. Optimum calli were induced on MS supplemented with 2.0 mg/l 2, 4‐D. The best callus growth and proliferation was recorded on MS fortified with 2.0 mg/l 2, 4‐D + 2.0 mg/l BAP + 0.5 mg/l NAA. The maximum embryonic calli were induced on MS + 2.0 mg/l 2, 4‐D + 2.0 mg/l Kn medium. Embryo induction, differentiation and maturation were obtained on MMS (MS +Vit B5). The rooted plantlets were produced on half strength MS without any supplements.The novelty of this study is the induction of embryos and plant regeneration from zygotic embryo explants of Hevea for the first time. The protocol developed in this study will facilitate mass propagation of high yielding rubber clones as well as to develop transgenic rubber plants with desired genes through genetic transformation.Plant Tissue Cult. & Biotech. 27(1): 51-61, 2017 (June)
Characterization of Progenies from Intergeneric Hybridization Between Oryza sativa L. and Porteresia coarctata (Roxb.) Tateoka
Authors: Islam Tasmia , Biswas Sudip , Mita Umme Habiba , Sarker RH , Rahman M Sazzadur , Ali M Ansar , Aziz KM Sultanul , Seraj Zeba Islam
Published: December 2017

Porteresia coarctata (Roxb.) Tateoka is an endemic halophyte growing all over the coastal belt of Bangladesh, propagating through rhizomes and setting a few ricelike grains. So exploiting the genetic potential of this wild rice as salt tolerant donor in possible wide crosses with rice (2n = 24) could be useful. We attempted intergeneric hybridization between Oryza sativa L. and P. coarctata. The survival rate of hybrid progenies in embryo culture was low but among them 2 hybrid plants were successfully matured from the intergeneric cross between the cultivated induced tetraploid of rice, Latisail (2n = 4x = 48) and P. coarctata (2n = 48). The hybrid plants could be successfully established in soil and were not like either of the parents in morphology although some of their features were similar to their maternal parent, Latisail (4x). Both of the hybrids were investigated through physiological analysis under salinity stress and molecular analyses with rice specific SSR markers. Molecular analysis of the F1 DNA with only 3 SSR markers, RM581, RM20224 and RM25271, out of 36 others tested, showed bands specific to both of the parents, while all had common bands with the maternal parent. Dendrogram analysis of the hybrids with the 36 SSR markers, show that P. coarctata forms a different clade and is clearly separated from Latisail and the hybrids. The putative hybrids however made a subgroup with Latisail. These observations could be possibly explained if chromosome loss of the paternal parent had occurred or may be it was a pleotropic effect of intergeneric hybridization. Physiological screening of the hybrid progenies at the F2 generation in seedling stage showed better result in leaf damage score (LDS) and salinity tolerance than their maternal parent Latisail (4x) at 150 mM salt stress for 10 days. F2 plants from one of the hybrid plants (H‐2) showed better performance but there was a large variation in response from each of the individual progenies. So, it is likely that some of the salt tolerant characteristics of the pollen parent might have been transferred to the recipient Latisail (4x). For introgression of better salt tolerant loci from P. coarctata, more wide hybrids will need to be produced and repeatedly crossed with P. coarctata.Plant Tissue Cult. & Biotech. 27(1): 63-76, 2017 (June)
High Frequency In vitro Regeneration of Gynura procumbens (Lour.) Merr.
Authors: Banu Tanjina Akhtar , Goswami Barna , Akter Shahina , Islam Mousona , Tanjin Tammana , Habib Ahashan , Khan Salim
Published: December 2017

An efficient rapid in vitro regeneration protocol was described from nodal segment, leaf and petiole explants. MS medium supplemented with 1.0 mg/l BAP and 0.5 mg/l IAA was found best for the multiple shoot formation from nodal segments. In this combination 99% explants produced multiple shoots and the average number of shoots per explants was 20.1 ± 1.96. For petiole and leaf explants best response was observed on MS supplemented with 2.0 mg/l BAP, 1 mg/l IAA and 0.5 mg/l Kn. Petiole explants produced highest mean number of shoots/explant (22.9 ± 1.728) among the three explants when the explants were cultured on MS with 2.0 mg/l BAP, 1 mg/l IAA and 0.5 mg/l Kn. The highest frequency of root induction (100%) and mean number of roots/plantlets (11.75) were obtained on MS. The rooted plantlets were transferred for hardening following acclimatization and finally were successfully established in the field.Plant Tissue Cult. & Biotech. 27(2): 207-216, 2017 (December)
Induced Pluripotent Stem Cell-Derived Red Blood Cells and Platelet Concentrates: From Bench to Bedside
Authors: Focosi Daniele , Amabile Giovanni
Published: December 2017

Red blood cells and platelets are anucleate blood components indispensable for oxygen delivery and hemostasis, respectively. Derivation of these blood elements from induced pluripotent stem (iPS) cells has the potential to develop blood donor-independent and genetic manipulation-prone products to complement or replace current transfusion banking, also minimizing the risk of alloimmunization. While the production of erythrocytes from iPS cells has challenges to overcome, such as differentiation into adult-type phenotype that functions properly after transfusion, platelet products are qualitatively and quantitatively approaching a clinically-applicable level owing to advances in expandable megakaryocyte (MK) lines, platelet-producing bioreactors, and novel reagents. Guidelines that assure the quality of iPS cells-derived blood products for clinical application represent a novel challenge for regulatory agencies. Considering the minimal risk of tumorigenicity and the expected significant demand of such products, ex vivo production of iPS-derived blood components can pave the way for iPS translation into the clinic.
Single Crystal Growth and Superconducting Properties of Antimony-Substituted NdO0.7F0.3BiS2
Authors: Demura Satoshi , Otsuki Satoshi , Fujisawa Yuita , Takano Yoshihiko , Sakata Hideaki
Published: December 2017

Antimony (Sb) substitution of less than 8% was examined on a single crystal of a layered superconductor NdO0.7F0.3BiS2. The superconducting transition temperature of the substituted samples decreased as Sb concentration increased. A lattice constant along the c-axis showed a large decrease compared with that along the a-axis. Since in-plane chemical pressure monotonically decreased as Sb concentration increased, the suppression of the superconductivity is attributed to the decrease in the in-plane chemical pressure.
Computational Modelling for Efficient Transdentinal Drug Delivery
Authors: Passos Agathoklis , Tziafas Dimitris , Mouza Aikaterini , Paras Spiros
Published: December 2017

This work deals with the numerical investigation of the delivery of potential therapeutic agents through dentinal discs (i.e., a cylindrical segment of the dentinal tissue) towards the dentin–pulp junction. The aim is to assess the main key features (i.e., molecular size, initial concentration, consumption rate, disc porosity and thickness) that affect the delivery of therapeutic substances to the dental pulp and consequently to define the necessary quantitative and qualitative issues related to a specific agent before its potential application in clinical practice. The computational fluid dynamics (CFD) code used for the numerical study is validated with relevant experimental data obtained using micro Laser Induced Fluorescence (μ-LIF) a non-intrusive optical measuring technique. As the phenomenon is diffusion dominated and strongly dependent on the molecular size, the time needed for the concentration of released molecules to attain a required value can be controlled by their initial concentration. Finally, a model is proposed which, given the maximum acceptable time for the drug concentration to attain a required value at the pulpal side of the tissue along with the aforementioned key design parameters, is able to estimate the initial concentration to be imposed and vice versa.
Computer Simulations of Static and Dynamical Properties of Weak Polyelectrolyte Nanogels in Salty Solutions
Authors: Sean David , Landsgesell Jonas , Holm Christian
Published: December 2017

We investigate the chemical equilibria of weak polyelectrolyte nanogels with reaction ensemble Monte Carlo simulations. With this method, the chemical identity of the nanogel monomers can change between neutral or charged following the acid-base equilibrium reaction HA ⇌ A− + H+. We investigate the effect of changing the chemical equilibria by modifying the dissociation constant K a . These simulations allow for the extraction of static properties like swelling equilibria and the way in which charge—both monomer and ionic—is distributed inside the nanogel. Our findings reveal that, depending on the value of K a , added salt can either increase or decrease the gel size. Using the calculated mean-charge configurations of the nanogel from the reaction ensemble simulation as a quenched input to coupled lattice-Boltzmann molecular dynamics simulations, we investigate dynamical nanogel properties such as the electrophoretic mobility μ and the diffusion coefficient D.
The Study of Geological Structures in Suli and Tulehu Geothermal Regions (Ambon, Indonesia) Based on Gravity Gradient Tensor Data Simulation and Analytic Signal
Authors: Lewerissa Richard , Sismanto Sismanto , Setiawan Ari , Pramumijoyo Subagyo
Published: December 2017

In early 2017, the geothermal system in the Suli and Tulehu areas of Ambon (Indonesia) was investigated using a gravity gradient tensor and analytic signal. The gravity gradient tensor and analytic signal were obtained through forward modeling based on a rectangular prism. It was applied to complete Bouguer anomaly data over the study area by using Fast Fourier Transform (FFT). The analysis was conducted to enhance the geological structure like faults as a pathway of geothermal fluid circulation that is not visible on the surface because it is covered by sediment. The complete Bouguer anomaly ranges of 93 mGal up to 105 mGal decrease from the southwest in Suli to the northeast in Tulehu. A high gravity anomaly indicates a strong magmatic intrusion below the Suli region. The gravity anomalies decrease occurs in the Eriwakang mountain and most of Tulehu, and it is associated with a coral limestone. The lower gravity anomalies are located in the north to the northeast part of Tulehu are associated with alluvium. The residual anomaly shows that the drill well TLU-01 and geothermal manifestations along with the Banda, and Banda-Hatuasa faults are associated with lowest gravity anomaly (negative zone). The gravity gradient tensor simulation and an analytic signal of Suli and Tulehu give more detailed information about the geological features. The gzz component allows accurate description of the shape structures, especially the Banda fault associated with a zero value. This result will be useful as a geophysical constraint to subsurface modeling according to gravity gradient inversion over the area.
Risk Factors for Internet Gaming Disorder: Psychological Factors and Internet Gaming Characteristics
Authors: Rho Mi , Lee Hyeseon , Lee Taek-Ho , Cho Hyun , Jung Dong , Kim Dai-Jin , Choi In
Published: December 2017

Background: Understanding the risk factors associated with Internet gaming disorder (IGD) is important to predict and diagnose the condition. The purpose of this study is to identify risk factors that predict IGD based on psychological factors and Internet gaming characteristics; Methods: Online surveys were conducted between 26 November and 26 December 2014. There were 3568 Korean Internet game users among a total of 5003 respondents. We identified 481 IGD gamers and 3087 normal Internet gamers, based on Diagnostic and Statistical Manual for Mental Disorders (DSM-5) criteria. Logistic regression analysis was applied to identify significant risk factors for IGD; Results: The following eight risk factors were found to be significantly associated with IGD: functional and dysfunctional impulsivity (odds ratio: 1.138), belief self-control (1.034), anxiety (1.086), pursuit of desired appetitive goals (1.105), money spent on gaming (1.005), weekday game time (1.081), offline community meeting attendance (2.060), and game community membership (1.393; p < 0.05 for all eight risk factors); Conclusions: These risk factors allow for the prediction and diagnosis of IGD. In the future, these risk factors could also be used to inform clinical services for IGD diagnosis and treatment.
Biomarkers for Pulmonary Inflammation and Fibrosis and Lung Ventilation Function in Chinese Occupational Refractory Ceramic Fibers-Exposed Workers
Authors: Zhu Xiaojun , Gu Yishuo , Ma Wenjun , Gao Panjun , Liu Mengxuan , Xiao Pei , Wang Hongfei , Chen Juan , Li Tao
Published: December 2017

Refractory ceramic fibers (RCFs) can cause adverse health effects on workers’ respiratory system, yet no proper biomarkers have been used to detect early pulmonary injury of RCFs-exposed workers. This study assessed the levels of two biomarkers that are related to respiratory injury in RCFs-exposed workers, and explored their relations with lung function. The exposure levels of total dust and respirable fibers were measured simultaneously in RCFs factories. The levels of TGF-β1 and ceruloplasmin (CP) increased with the RCFs exposure level (p < 0.05), and significantly increased in workers with high exposure level (1.21 ± 0.49 ng/mL, 115.25 ± 32.44 U/L) when compared with the control group (0.99 ± 0.29 ng/mL, 97.90 ± 35.01 U/L) (p < 0.05). The levels of FVC and FEV1 were significantly decreased in RCFs exposure group (p < 0.05). Negative relations were found between the concentrations of CP and FVC (B = −0.423, p = 0.025), or FEV1 (B = −0.494, p = 0.014). The concentration of TGF-β1 (B = 0.103, p = 0.001) and CP (B = 8.027, p = 0.007) were associated with respirable fiber exposure level. Occupational exposure to RCFs can impair lung ventilation function and may have the potential to cause pulmonary inflammation and fibrosis. TGF-β1 and CP might be used as sensitive and noninvasive biomarkers to detect lung injury in occupational RCFs-exposed workers. Respirable fiber concentration can better reflect occupational RCFs exposure and related respiratory injuries.
The Influence of Industry Characteristics and Dynamic Capabilities on Firms’ Profitability
Authors: Pervan Maja , Curak Marijana , Pavic Kramaric Tomislava
Published: December 2017

The aim of this research was to explore one of the most intriguing dimensions of every firm’s business—its performance. Aside from analysing the influence of industry’s characteristics on the firm’s performance, the authors addressed the characteristics of dynamic capabilities and their role in contribution to the firm’s ultimate success. The analysis was conducted on a sample of 118 small Croatian manufacturing companies. The application of the Structural Equation Modelling (SEM) approach revealed a statistically significant influence of both the industry’s characteristics (represented by Porter’s five forces framework) and dynamic capabilities (based on Teece’s theory) on the firm’s performance, where the influence of dynamic capabilities is proven to be larger than that of the industry.
Development of Novel Therapeutic Agents by Inhibition of Oncogenic MicroRNAs
Authors: Nguyen Dinh-Duc , Chang Suhwan
Published: December 2017

MicroRNAs (miRs, miRNAs) are regulatory small noncoding RNAs, with their roles already confirmed to be important for post-transcriptional regulation of gene expression affecting cell physiology and disease development. Upregulation of a cancer-causing miRNA, known as oncogenic miRNA, has been found in many types of cancers and, therefore, represents a potential new class of targets for therapeutic inhibition. Several strategies have been developed in recent years to inhibit oncogenic miRNAs. Among them is a direct approach that targets mature oncogenic miRNA with an antisense sequence known as antimiR, which could be an oligonucleotide or miRNA sponge. In contrast, an indirect approach is to block the biogenesis of miRNA by genome editing using the CRISPR/Cas9 system or a small molecule inhibitor. The development of these inhibitors is straightforward but involves significant scientific and therapeutic challenges that need to be resolved. In this review, we summarize recent relevant studies on the development of miRNA inhibitors against cancer.
Harnessing Invariant NKT Cells to Improve Influenza Vaccines: A Pig Perspective
Authors: Yang Guan , Richt Jürgen , Driver John
Published: December 2017

Invariant natural killer T (iNKT) cells are an “innate-like” T cell lineage that recognize glycolipid rather than peptide antigens by their semi-invariant T cell receptors. Because iNKT cells can stimulate an extensive array of immune responses, there is considerable interest in targeting these cells to enhance human vaccines against a wide range of microbial pathogens. However, long overlooked is the potential to harness iNKT cell antigens as vaccine adjuvants for domestic animal species that express the iNKT cell–CD1d system. In this review, we discuss the prospect of targeting porcine iNKT cells as a strategy to enhance the efficiency of swine influenza vaccines. In addition, we compare the phenotype and tissue distribution of porcine iNKT cells. Finally, we discuss the challenges that must be overcome before iNKT cell agonists can be contemplated for veterinary use in livestock.
Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils
Authors: Lin Tzu-Kai , Zhong Lily , Santiago Juan
Published: December 2017

Plant oils have been utilized for a variety of purposes throughout history, with their integration into foods, cosmetics, and pharmaceutical products. They are now being increasingly recognized for their effects on both skin diseases and the restoration of cutaneous homeostasis. This article briefly reviews the available data on biological influences of topical skin applications of some plant oils (olive oil, olive pomace oil, sunflower seed oil, coconut oil, safflower seed oil, argan oil, soybean oil, peanut oil, sesame oil, avocado oil, borage oil, jojoba oil, oat oil, pomegranate seed oil, almond oil, bitter apricot oil, rose hip oil, German chamomile oil, and shea butter). Thus, it focuses on the therapeutic benefits of these plant oils according to their anti-inflammatory and antioxidant effects on the skin, promotion of wound healing and repair of skin barrier.
Pt(IV)/Re(I) Chitosan Conjugates as a Flexible Platform for the Transport of Therapeutic and/or Diagnostic Anticancer Agents
Authors: Gabano Elisabetta , Do Quental Letícia , Perin Elena , Silva Francisco , Raposinho Paula , Paulo António , Ravera Mauro
Published: December 2017

New chitosan derivatives modified with (3-carboxypropyl)trimethylammonium chloride (1) and coupled with (OC-6-44)-diammine(4-carboxypropanoato)dichloridoethanolatoplatinum(IV) (2), were synthesized and their preliminary biological evaluation carried out in human tumor cells. Some of these derivatives were also loaded with a chelating ligand (3) that was derived from bis(quinolin-2-ylmethyl)amine to obtain chitosan-based nanoparticles for an EPR-mediated delivery of Pt(IV) prodrugs and Re(I) tricarbonyl complexes (4), to explore a multimodal theranostic approach to cancer. The cytotoxicity of the different chitosan conjugates (C12, C123, and C1234), carrying different combinations of the Pt(IV) complex, the chelator and the Re(I) complex, was evaluated in the A2780 human ovarian cancer cell line using the MTT assay. The Pt(IV)-containing nanosystems showed low to moderate cytotoxic activity (IC50 values in the range 13.5–33.7 µM) and was comparable to that found for the free Pt(IV) complex (IC50 = 13.7 µM). Therefore, the Pt(IV)-chitosan conjugation did not enhance the cytotoxic activity of the Pt(IV) prodrug, which certainly reflects the inefficient cellular uptake of the nanoconjugates. Nevertheless, a clearer view of their potential for the delivery of anticancer agents requires further in vivo tests because the EPR effect increases extravasation and retention within the tumor tissue, not necessarily within the tumor cells.
Investigation on Synthesis, Stability, and Thermal Conductivity Properties of Water-Based SnO2/Reduced Graphene Oxide Nanofluids
Authors: Yu Xiaofen , Wu Qibai , Zhang Haiyan , Zeng Guoxun , Li Wenwu , Qian Yannan , Li Yang , Yang Guoqiang , Chen Muyu
Published: December 2017

With the rapid development of industry, heat removal and management is a major concern for any technology. Heat transfer plays a critically important role in many sectors of engineering; nowadays utilizing nanofluids is one of the relatively optimized techniques to enhance heat transfer. In the present work, a facile low-temperature solvothermal method was employed to fabricate the SnO2/reduced graphene oxide (rGO) nanocomposite. X-ray diffraction (XRD), thermogravimetric analysis (TGA), X-ray photoelectron spectroscope (XPS), Raman spectroscopy, and transmission electron microscopy (TEM) have been performed to characterize the SnO2/rGO nanocomposite. Numerous ultrasmall SnO2 nanoparticles with average diameters of 3–5 nm were anchored on the surface of rGO, which contain partial hydrophilic functional groups. Water-based SnO2/rGO nanofluids were prepared with various weight concentrations by using an ultrasonic probe without adding any surfactants. The zeta potential was measured to investigate the stability of the as-prepared nanofluid which exhibited great dispersion stability after quiescence for 60 days. A thermal properties analyzer was employed to measure thermal conductivity of water-based SnO2/rGO nanofluids, and the results showed that the enhancement of thermal conductivity could reach up to 31% at 60 °C under the mass fraction of 0.1 wt %, compared to deionized water.
Application of NMR Screening Methods with 19F Detection to Fluorinated Compounds Bound to Proteins
Authors: Furihata Kazuo , Usui Moe , Tashiro Mitsuru
Published: December 2017

The combinational use of one-dimensional (1D) NMR-based screening techniques with 1H and 19F detections were applied to a human serum albumin–diflunisal complex. Since most NMR screening methods observe 1H spectra, the overlapped 1H signals were unavailable in the binding epitope mapping. However, the NMR experiments with 19F detection can be used as an effective complementary method. For the purpose of identifying the 1H and 19F binding epitopes of diflunisal, this paper carries out a combinatorial analysis using 1H{1H} and 19F{1H} saturation transfer difference experiments. The differences of the 1H-inversion recovery rates with and without target irradiation are also analyzed for a comprehensive interpretation of binding epitope mapping.