bluuebunny/crossref_metadata_2025 huggingface dataset:
Determinants of Risk Factors on the Event of Lung Tb
Authors: Perangin-Angin Susanti br , Sihombing Nurmala Hayati
Published: May 2022

Pulmonary tuberculosis (TB) is one of the most prevalent infectious diseases in the world. Based on a report by the World Health Organization (WHO, 2012) one third of the world's population, which is around two billion people infected with Mycobacterium Tuberculosis. More than 8 million populations get active TB every year and around 2 million die. More than 90% of TB cases and deaths come from developing countries, one of which is in Indonesia. This research is an observational analytic study with a case control study design that aims to determine the effect of risk factors for pulmonary TB events using a retrospective approach. The results of this study indicate that the most dominant variable TB incidence in high school education cases is down to 45 people (97.8%) and the smallest House Density is 25 people (54.3%) and the most dominant control variable is no comorbidities namely as many as 47 people (97.9%) and the smallest Respondents' House Density fulfilled the requirements of 26 people (56.5%). Factors that significantly influence the incidence of pulmonary tuberculosis are nutritional status (p = 0,000, OR = 31,263), respondent employment (p = 0,000, OR = 21.77), comorbidities (p = 0,000, OR = 0.022), Ventilation (p = 0.001, OR = 4,680) and House Humidity (p = 0,000, OR = 9,625). The results of the study concluded that the variable that most influenced the incidence of pulmonary TB was Nutrition Status (p = 0.002, Exp (B) = 2.334).
MSMe Export Finance Go Internasional
Authors: Hastutik Sri , Sudarmiatin Sudarmiatin , Bidin Rosmiza
Published: May 2022

The aim is to find out the obstacles that occur to MSMEs that go International in the payment of Kendang Djimbe's export finances and their settlement. Descriptive qualitative research method. This research wants to explore something new, which is not widely known by the public, so it wants to be studied more deeply. With the aim of describing the ongoing phenomenon when the research was carried out and examining the causes and effects of constrained export finance payments. The analytical tool used is fishbone analysis (Fishbone Diagram). Research sites on SMEs "Kendang Djimbe" as a Creative Industry in Blitar. Ten respondents interviewed related to the export of “Kendang Djimbe” to foreign countries. The key informant is the exporter of “Kendang Djimbe” to China. The result of the source of the problem that is an obstacle for Kendang Djimbe MSMEs in Blitar, is the lack of understanding of knowledge about export finance towards Go International. MSMEs in solving problems in financial transactions for exports of Djimbe Kendang Crafts, knowing and having good knowledge of the payment system, choosing a goods delivery system according to the agreement, being able to calculate the export selling price correctly, knowledge of their export permits and finding the right buyer. The originality of previous researchers examining trade barriers in exports, this
Pronominal Affix of Bugic Language Enjoyable Dialec
Authors: Rahim Abd. Rahman
Published: May 2022

In terms of social strata, the same language has different variations if it is spoken by groups of people with lower-middle social strata and upper-middle social strata. This study aims to describe the variation of Bugis pronominal affixes in the Ennak dialect used by Bugis speakers in Sinjai Regency. This research is classified into the type of qualitative descriptive research. The data in this study are the speeches of the Bugis people in Sinjai Regency or the Ennak dialect. Data collection was carried out by speaking and tapping techniques. This study uses intralingual equivalent data analysis. Data that is compared with intralingual equivalents are differences and similarities which have other names, namely HBS (Same Comparative Relations) and HBB (Different Comparative Relations), both of which are advanced techniques in data analysis. The results showed that the use of Bugis pronominal affixes in the Ennak dialect consisted of proclitic and enclitic. has a different style from the use of the clitic form in Indonesia.
SPOTLIGHT ON THE ASSOCIATION BETWEEN NANOBACTERIA AND SOME HUMAN DISEASES
Authors: Elshafei Ali Mohamed
Published: May 2022

Nanobacteria are the smallest cell-walled bacteria, recently discovered in human and commercial cell culture serum, also known as calcifying nanoparticles (CNPs). Nanobacteria are the name of a proposed class of living organisms particularly cell-walled microorganisms with a size much smaller than the generally accepted lower limit size for life (about 200nm). Recently, histopathological immunohistochemical staining, transmission electron microscopy (TEM), and calcific staining studies revealed the association of nanobacteria in kidney and gall stones. Nanobacteria have been appeared to contribute to different benign and malignant calcifications in the form of calcium phosphate crystals and contribute to malignant calcifications in breast and ovarian cancer. Nanobacteria also cause prostatic stones in patients with chronic pelvic pain syndrome due to chronic prostatitis and are present in dental and pulp calculus. The evidence that nanobacteria exist within the human body and are closely related to numerous sorts of diseases is now overpowering. However, future research is required to reveal their nature and impact on health and disease. This paper aimed to highlight the harmful role of nano-bacteria on human health and to describe the association of nanobacteria and their hypothesized relationship with some human diseases.
NANOTECHNOLOGY STRATEGY AS ANTIBACTERIAL: A PRIMER FOR THE NOTICE
Authors: Ibisanmi Tope Abraham , Aribisala Jamiu  Olaseni
Published: May 2022

Multidrug-resistant (MDR) bacteria pose a major threat to all fields of medical science as it can result in treatment failure which can have severe consequences, especially in case of critical patients. The availability of new antibacterial agents appeared to be a very complex process. One of the most important aspect of modern field research is nanotechnology, it deals with synthesis, design and manipulation of particles structures ranging from approximately 1-100nm. Nanoparticles (NPs) are of great importance in areas like health care, cosmetics, food and feed, environmental health e.t.c. Nanoparticles matrix properties and constituent materials can be used to categorized them into inorganic and organic nanosystems. Techniques use within the synthesis of NPs includes; chemical, physical, chemistry, and biological methods, every methodology has its advantages and disadvantages with common issues of value, quantifiability and uniform particle size. Famous microbiologist Alexander Fleming said that “There is probably no chemotherapeutic drug to which in suitable circumstances the bacteria can not react by in some way acquiring fastness.” thus, there's high chance that the organism can also become resistance to newly developed medication at later stage. To this end NPs are considered to be good antibacterial agents and may overcome the barrier of MDR owing to their ability to anchor to the bacterial cell wall, multifunctional mechanisms to intervene normal cell functionality and subsequently penetrate it, thereby causing structural changes in the cell membrane permeability leading to cell death.
TITLE OF MANUSCRIPT: ENHANCEMENT OF LIPOLYTIC CHARACTERISTICS OF A PALM-OIL MILL EFFLUENT-SOURCED KODAMAEA OHMERI PL2
Authors: Odeniyi Olubusola , Ajileye Olamide
Published: May 2022

The hydrolysis of long-chain triglycerides and fats is catalyzed by lipases, important enzymes which have essential biotechnological, medical, and industrial roles. Fungi were isolated from palm-oil mill wastes and screened for their lipid-hydrolyzing potentials. Lipase production and activity characteristics were determined using different substrates. Sixteen, out of the 75 fungi isolated, exhibited lipolytic characteristics. Yeast isolate PL2 gave the highest zone of hydrolysis (44.5 mm) and was identified as Kodamaea ohmeri. This yeast was cultured under diverse media conditions for lipase production and the enzyme produced under each physicochemical condition was determined spectrophotometrically. The optimum parameters for lipase production (1% Tween-80, Ca2+, peptone, 37°C and pH 6) were used to produce lipase which was further purified through (NH4)2SO4 precipitation, membrane dialysis and gel chromatography. The activity of the partially purified lipase increased progressively with each purification stage. The lipase had optimum activity at 50oC and was alkalophilic with peak pH for enzymatic hydrolysis at 8.0. The lipase was supported by 0.5% concentrations of SDS and Triton X-100 (129.9 and 129.4%, respectively), and a 100-fold activity increase with 0.5% Tween-80. Lipase activity was augmented by Manganese and calcium ions (10 mM) but inhibited by NH4+, Fe3+ and Na+. The use of Tween-80 resulted in increased enzyme yield as well as better enzyme characteristics compared to other substrates. The knowledge obtained in this study may be harnessed for commercialization of Kodamaea ohmeri lipase.
ТЕОРЕТИЧЕСКИЕ ОСНОВЫ УПРАВЛЕНИЯ ИНВЕСТИЦИОННОЙ ДЕЯТЕЛЬНОСТЬЮ СТРАХОВЫХ КОМПАНИЙ
Authors: Байсаева Малика Усмановна
Published: May 2022

Современные условия развития отечественной экономики значительно влияют на результаты деятельности страховых компаний и обусловливают потребность в поиске дополнительных источников получения дохода. Поэтому инвестиционная деятельность выступает достаточно важной составляющей, которая дает возможность получать дополнительные доходы для того, чтобы страховщик мог успешно осуществлять свою основную деятельность, тем самым обусловлена актуальность выбранной темы. На сегодняшний день инвестиционная деятельность страховщиков в нашей стране остается недостаточно развитой, а ее потенциал нереализованным. Но в перспективе она способна обеспечить подъем экономики России.
Целью работы является обоснование сущностно-теоретических основ и раскрытие особенностей инвестиционной деятельности страховщиков.
Предмет исследования: теоретические основы управления инвестиционной деятельностью в страховых компаниях.
ОЦЕНКА РАЗВИТИЯ ИННОВАЦИОННЫХ ПРОЦЕССОВ В РФ: ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ РАЗВИТИЯ
Authors: Хамурадов Мовсар Ахметпашович , Вахаева Сацита Адамовна
Published: May 2022

В данной научной статье выявлена актуальность инновационного развития экономики и ее значимость для стабильного экономического роста в современных условиях. Исследованы инновационные процессы в стране за последние годы. В результате проведенного анализа инновационных процессов сделаны выводы, выявлены проблемы, препятствующие эффективному развитию инноваций в стране. На основании оценки инновационных процессов и выявленных проблем, предложены меры по развитию инноваций в стране и становлению инновационно-ориентированной экономики страны.
НЕКОТОРЫЕ УТОЧНЕНИЯ НАУЧНЫХ ПОНЯТИЙ, АКТИВНО ИСПОЛЬЗУЕМЫХ В ЭКОНОМИЧЕСКИХ И ФИНАНСОВЫХ ИССЛЕДОВАНИЯХ
Authors: Токаев Нох Хасанбиевич , Баснукаев Муса Шамсудинович
Published: May 2022

В статье сформированы научные подходы к теоретическому истолкованию системно используемых в различных публикациях и официальных документах понятий, характеризующих экономическое развитие, финансовые отношения, социальные реальности. Раскрыты смысловые особенности экономического и финансового бюджетного роста и развития. Уточнены определенности, меры и границы расходования финансовых и бюджетных средств.
КРИПТОЭКОНОМИКА КАК ПРОДУКТ ЭВОЛЮЦИИ ФИНАНСОВЫХ АКТИВОВ
Authors: Исраилова Залина Руслановна , Вахаева Марет Абдылхамидовна , Шаипова Хава Абдулаевна
Published: May 2022

Криптоэкономика ведет к развитию альтернативной финансовой и технологической инфраструктуры, которая является глобальной, с открытым исходным кодом и доступна для всех, кто имеет доступ к Интернету, независимо от национальности, этнической принадлежности, расы, пола и социально-экономического класса. Основное повествование о криптовалютах, как правило, касалось спекулятивного и рискованного характера этого нового класса инвестиционных активов, его использования в киберпреступности и темной сети, негативных последствий майнинга для ESG (параметры, на которые ориентируется бизнес в разработке стратегий устойчивого развития) и в некоторых случаях виктимизации неосведомленных потребителей. В статье рассмотрена экономическая природа криптовалюты, ее развитие, преимущества и недостатки, а также проблемы, связанные с термином «криптоэкономика».
ОСОБЕННОСТИ СПРОСА И ЦЕНООБРАЗОВАНИЯ НА МИРОВОМ РЫНКЕ МЕБЕЛИ
Authors: Аджимет Гульнара Халидовна , Аблязова Севиль Нуриева
Published: May 2022

В статье рассмотрен мировой рынок мебели. Установлено, что рост объемов международной торговли мебелью в настоящее время обусловлен процессами глобализации в результате сдвигов в размещении мебельного производства и устойчиво высокими темпами роста объемов экспорта в странах Юго-Восточной Азии, Латинской Америки и Восточной Европы. Отмечено, что стремительное развитие современной науки и техники способствует развитию и совершенствованию технологий производства мебели, процесс производства мебели достиг высокой степени механизации и автоматизации, появились новые направления в совершенствовании технологий. Проанализированы особенности спроса и ценообразования на мировом рынке мебели. Рассмотрена структура спроса на мебель в Интернете. Исследована структура спроса на мебель в мире по категориям 2019-2020 гг. Изучена структура спроса с уточнением по типу помещения, структура спроса с уточнением по типу мебели. Авторами установлены ведущие страны производителей мебели 2020 гг. Дана краткая характеристика факторам ценообразования мебельной продукции и факторам, влияющим на ценообразование различных категорий мебели.
УПРОЩЕННАЯ СИСТЕМА УЧЕТА И НАЛОГООБЛОЖЕНИЯ: ЦЕЛИ, ПРОБЛЕМЫ, ПЕРСПЕКТИВЫ
Authors: Маккаева Разет Сайд-Аминовна , Асхабов Камал Махмудович , Шовхалов Нурид Бесланович
Published: May 2022

В статье рассматриваются основные положения организации бухгалтерского учета и налогообложения на малых предприятиях. В связи с постоянно меняющейся экономической обстановкой бухгалтерский учет на предприятиях малого бизнеса постоянно совершенствуется. Ввиду постоянно вносимых изменений в нормативно-правовые акты и документы упрощенного порядка ведения учета и отчетности, выдвигается на первый план вопрос касательный науки и практики в области учета и отчетности на предприятиях малого бизнеса. Учитывая эти изменения в нашей стране, происходящие на сегодняшний день, данное исследование предусматривает выявление и изучение особенностей, подходов и упрощенного варианта ведения бухгалтерского учета и налогообложения на малых предприятия, сохраняя учетные данные с их аналитическими ценностями.
АКТУАЛЬНЫЕ ВОПРОСЫ «ЗЕЛЕНОЙ» ЭКОНОМИКИ
Authors: Пайтаева Комета Тахировна
Published: May 2022

Нынешний этап развития экономики отличается масштабной трансформацией всех сфер деятельности. Особое место занимают преобразования, характеризующие взаимоотношения между человеком и окружающей природной средой.
В статье рассматриваются приоритеты, цели, принципы «зеленой» экономики в современных условиях. Перечислены и охарактеризованы отдельные положения актуальных нормативно-правовых актов, регулирующих взаимосвязанные вопросы экологии и экономики в Российской Федерации. Отмечено, что в нашей стране проводится последовательная работа по экологизации экономики и обеспечению государственной поддержки инвестиционных проектов, отвечающих требованиям современной промышленной и экологической безопасности.
УСТОЙЧИВОЕ РАЗВИТИЕ КАК НОВАЯ МОДЕЛЬ РАЗВИТИЯ ОБЩЕСТВА
Authors: Шахгираев Исмаил Увайсович , Салгериева Нура Ширваниевна , Дудаев Турпал Али Масудович
Published: May 2022

Устойчивое развитие стало популярной фразой в современном дискурсе развития. Однако, несмотря на широкое распространение и огромную популярность, которую она приобрела на протяжении многих лет, эта концепция все еще кажется неясной, поскольку многие люди продолжают задавать вопросы о ее значении и истории, а также о том, что она влечет и подразумевает для теории и практики развития. Цель этой статьи - внести свой вклад в обсуждение устойчивого развития путем дальнейшего объяснения парадигмы и ее последствий для человеческого мышления и действий в поисках устойчивого развития.
ТРАНСФОРМАЦИИ В ИПОТЕЧНОМ КРЕДИТОВАНИИ СОВРЕМЕННОГО ГОСУДАРСТВА
Authors: Макшарипова Эльза Аслановна , Цакаев Алхазур Харонович
Published: May 2022

В современных реалиях нестабильности экономики России, обусловленной историческими факторами, санкциями, пандемией и пр., развитие ипотечного кредитования является необходимым для населения и государства. Ипотечное кредитование в России претерпевало изменения на различных этапах исторического развития, и в современном виде получило свое становление относительно недавно. Опыт зарубежных стран (стран Западной Европы, США, Китая) может способствовать выработке собственного, оптимального именно для нашей страны, пути развития ипотечного кредитования. В статье проведен анализ систем ипотечного кредитования в России и за рубежом, выявлены основные проблемы в современной модели ипотечного кредитования, а также определены пути совершенствования современного механизма ипотечного кредитования.
К ВОПРОСУ О ВЛИЯНИИ МЕЖБАНКОВСКОЙ КОНКУРЕНЦИИ НА УСТОЙЧИВОСТЬ НАЦИОНАЛЬНОЙ БАНКОВСКОЙ СИСТЕМЫ
Authors: Мусханова Хеда Жамуловна , Тавбулатова Эльза Арбиевна
Published: May 2022

В статье исследуются проблемы межбанковской конкуренции на российском рынке банковских услуг в условиях мировых трансформаций и волатильности. Рассмотрены теоретические аспекты межбанковской конкуренции, изучены факторы, оказывающие негативное воздействие на ее развитие. Авторами проанализирован обширный материал, характеризующий современное состояние и развитие российской банковской системы с использованием отчетов и докладов Банка России. Использование системного и комплексного подходов исследования позволили выявить основные тенденции развития межбанковской конкуренции среди кредитных организаций России. На основе проведенного анализа определен авторский подход к категориальному аппарату «межбанковская конкуренция», выявлены условия, способствующие развитию естественной конкурентной среды на российском банковском рынке в условиях санкционных ограничений глобального характера.
РАБОТА МФО КАК МИКРОКРЕДИТНОЙ ОРГАНИЗАЦИИ В ЭКОНОМИКЕ РОССИИ
Authors: Успаева Милана Гумкиевна
Published: May 2022

На современном этапе развития финансово-экономических отношений важна объективная гибкость взглядов относительно теорий и научных направлений в вопросах анализа первопричин принятия решений субъектами на финансовом рынке.
В основном это обусловлено появлением новых направлений, исследующих поведение индивидуумов не исключительно с точки зрения классических подходов, а обращаются к психологическим аспектам, которые влияют на экономический выбор человека. Сейчас это является сферой исследования поведенческой экономики.
Классическая модель принятия финансовых решений базируется на понятии «рациональности» и предусматривает, что лицо, принимающее решение, должно мыслить совершенно рационально и логично, иметь четко определенную цель, владеть имеющейся информацией и направлять все свои действия на выбор наилучшей альтернативы, которая будет способствовать максимизации результата деятельности.
Но с развитием экономических отношений ученые начали замечать, что классические экономические теории не могут объяснить все финансовые решения, поскольку на практике нередко поведение людей отличается от того, что описывает теория. В ответ на неудачи основных классических теорий в объяснении аномалий на финансовых рынках возникла поведенческая модель принятия решений. Именно поведенческая экономика сумела объяснить, почему индивидуумы принимают иррациональные экономические решения, показала, как стереотипность мышления, эмоции, когнитивные предубеждения влияют на личные финансовые ресурсы и их выбор.
ЗАВИСИМОСТЬ ЭКОНОМИКИ ОТ ВЫБОРА ФОРМ СОБСТВЕННОСТИ
Authors: Булгучев Мурат Хамзатович
Published: May 2022

В целом население Российской Федерации (РФ) издавна практиковало в основном коллективный труд. Недоверчиво относились в стране к человеку, занятому индивидуальной трудовой деятельностью. А в период СССР (Союз Советских Социалистических Республик) в течении 70 лет вообще отреклись от частной формы собственности.
Теряя в таком случае основной инструментарий открытой экономики, конкуренция, экономика стала отставать от стран с традиционно рыночным хозяйствованием. В итоге Советский Союз распался, оставив населению 30-летний переходный период с бедной экономикой для основного населения, особенно в регионах.
Omalizumab in the severe exacerbations of seasonal allergic rhinitis
Authors: Pavlova Ksenia S. , Kulichenko Darya S. , Kurbacheva Oksana M. , Dyneva Miramgul E. , Ilina Natalia I.
Published: May 2022

BACKGROUND: According to the Federal Clinical Guidelines, patients with severe persistent allergic rhinitis and/or severe exacerbation who failed to respond to third-line pharmacotherapy (antihistamines, leukotriene receptor antagonists, nasal corticosteroids) are advised to consider the administration of omalizumab. However, there is a lack of practical recommendations guiding the regimens and duration of the omalizumab therapy in the severe exacerbation of seasonal allergic rhinitis.
AIMS: To assess the efficacy of omalizumab additional therapy in patients with severe exacerbation of allergic rhinitis during the pollen season, and to determine the optimal regimen and duration of treatment.
MATERIALS AND METHODS: This is an open observational uncontrolled prospective single-center study. 10 adult patients with severe exacerbation of seasonal allergic rhinitis due to birch pollen were selected for the study. All of them received the third-line of therapy according to Federal Clinical Guidelines and had absence or incomplete control: Total nasal symptom score 2. All of them were treated with omalizumab. The dose and regime were prescribed according to instructions that took into account the overall IgE level, as well as the patients weight. Daily symptom diaries and the need for rescue medication levels were evaluated. The primary endpoint had a decrease in the Combined Medical and Symptom Score mean.
RESULTS: The additional omalizumab treatment improved allergic rhinitis control for all patients and also reduced the rescue medication (TNSS 1.8 [95% CI 1.562.04]; р 0.001, and CMSS 2.12 [95% CI 1.742.5]; р 0.001, by the end of 1 week after the first omalizumab injection; TNSS 2.53 [95% CI 2.053.01]; р 0.0001, and CMSS 5.22 [95% CI 4.745.7]; р 0.001, by the end of four weeks, respectively). It was noted that the omalizumab effect realization occurs for some time (37 days). Due to short-season pollen for birch (12 months), the duration of treatment in our study did not exceed one month, so we managed to achieve complete control over the symptoms in all patients by the omalizumab with a small multiplicity of injections (12 injections). No adverse events were registered during the study.
CONCLUSION: Omalizumab additional therapy in patients with severe exacerbation of allergic rhinitis allows control of all symptoms. Taking into account the mechanism of its action, omalizumab should be administered at least a week before the expected pollen season in patients with severe exacerbation (according to the previous seasons) who did not complete their allergen-specific immunotherapy on time, and continue therapy till the end of the pollen season.
Knowledge and Behavior of Antibiotic Use among PKK Women (Family Welfare Empowerment) with Career Women Status in Banjar Yangbatu Kauh, East Denpasar
Authors: Megawati Fitria , Agustini Ni Putu Dewi
Published: May 2022

Antibiotics are drugs that are often prescribed by doctors to treat infections. Lack of public knowledge about the use of antibiotics causes antibiotic resistance. To overcome the irrational use of antibiotics, it is necessary to increase the knowledge and behavior of parents about the use of antibiotics. The purpose of this study was to determine the level of knowledge and behavior of using antibiotics in PKK (Family Welfare Empowerment) mothers who were career women in the Yangbatu Kauh Banjar, East Denpasar. This research is a descriptive research using accidental sampling technique. The distributed questionnaires were tested for validity and reliability by distributing questionnaires to 30 trial respondents. The questionnaire is declared valid if it has a calculated r value > 0.361, and the Cronbach Alpha reliability test using SPSS version 22 was tested with a 95% confidence level, the questionnaire data was declared reliable with a value of 0.914 on the level of knowledge and a value of 0.810 on behavior. The results obtained based on the age characteristics of the most respondents, namely respondents aged 42-47 years as much as 51.28%. On the characteristics of the respondents based on the level of education the most were SMA/SMK as much as 58.97% and on the characteristics of the type of work the most were private employees as much as 64.10%. The level of knowledge of PKK mothers who are career women is in the good category with a percentage of 69.23% as many as 27 people and the behavior of PKK mothers who are career women is in the good category with a percentage of 82.05% as many as 32 people. So, from these results, PKK mothers who are career women in Banjar Yangbatu Kauh, East Denpasar have a good level of knowledge and behavior in the use of antibiotics.
PROGNOSTIC CRITERIA OF EXCESSIVE BODY WEIGHT DEVELOPMENT AMONG SCHOOLCHILDREN BY THE RESULTS OF ANAMNESTIC SURVEY
Authors: Diachuk Dmytro , Yashchenko Yurii , Zabolotna Iryna
Published: May 2022

The aim: To elaborate prognostic criteria to assess the risk of excessive body weight development among schoolchildren on the basis of hereditary and behavioral predictors.
Materials and methods: 90 parents of school age children were interviewed by means of the social study method.
Results: Hereditary status (1 and 2 congeniality degree to type 2 diabetes mellitus, arterial hypertension, excessive body weight, cases of myocardial infarction and/or stroke available among relatives) and behavioral characteristics (peculiarities of diet and physical activity of a child) were studied among school age children. The risks promoting development of an excessive body weight under conditions of hereditary and behavioral factors were assessed. The prognostic matrix elaborated enables to predict development of an excessive body weight of a child under a comprehensive effect of unfavorable hereditary and behavioral characteristics with a high accuracy (AUC = 0,88, Std. Dev. = 0,0451).
Conclusions: The method elaborated enables to find children with the risk of an excessive body weight development and introduce individualized prophylaxis measures in order to prevent development of obesity and diseases associated with an excessive body weight.
HYGIENIC ASSESSMENT OF THE INFLUENCE OF PESTICIDES ON THE FATTY COMPOSITION OF SUNFLOWER SEED LIPIDS
Authors: Hulai Tetiana , Kuzminska Olena , Omelchuk Sergiy , Hrynzovskyi Anatolii , Trunina Tetiana , Blagaia Anna V.
Published: May 2022

The aim: Evaluation of the influence of plant protection chemicals on the fatty acid composition of sunflower seeds.
Materials and methods: Study of the effects of pesticides, study of the effects of pesticides on the fatty acid composition (lipid) of sunflower seed by gas-liquid chromatography was studied.
Results: It was found that the content of oleic and linoleic unsaturated fatty acids did not differ significantly from the control. The content of linolenic and arachidonic acids was at the level of the control group. A similar pattern was observed in relation to the content of saturated fatty acids, in particular myristic, pentodecanoic, palmitic, margaric, stearic. The total content of fatty acids (unsaturated fatty acids and saturated fatty) selected under different seed protection schemes did not differ significantly from control.
Conclusions: It is proved that the application of the investigated pesticides in various schemes of chemical protection of sunflower crops does not affect the nutritional and biological value of the seeds.
EVALUATION OF COVID-19 VACCINES EFFICACY IN IRAQI PEOPLES
Authors: Jawad Mahmood J. , Jawad Mohammed J. , Hasan Iman Sabeeh , Hassan Saif M. , Fatima Ghizal , Hadi Najah R.
Published: May 2022

The aim: The present study was carried out on patients recovered from COVID-19, including those patients who have taken vaccine and those who have not.
Materials and methods: The patients were recruited via an online panel and surveyed at different regions of Iraq from June 1, 2021, to August 30, 2021.
Results: Our results demonstrated that the highest percentage of people recommended Pfizer vaccine followed by Sinopharm, while AstraZeneca vaccine was least recommended.
Conclusions: The efficacy of different vaccines differed significantly; the highest effectiveness was observed with Pfizer vaccine followed by AstraZeneca and Sinopharm with effectiveness ranging from 94%, 89%, and 74%, respectively. Further, the highest percentage of re-infected patients was observed with Sinopharm vaccine followed by Astra Zeneca and Pfizer vaccine, respectively. Also, the highest percent of re-infection with masking used was seen in the case of Sinopharm vaccine followed by AstraZeneca and Pfizer vaccine. Although, we observed that post-vaccination symptoms were lowest than pre-vaccination symptoms, the percent of asymptomatic cases post-vaccination was highest than pre-vaccination cases for all vaccines.
THE RELATIONSHIPS OF IRS-1 POLYMORPHISM WITH HEMODYNAMIC DISORDERS IN HYPERTENSIVE PATIENTS DEPENDING ON BODY WEIGHT AND METABOLIC COMORBIDITY
Authors: Psarova Valentyna , Kochuieva Maryna , Gogunska Inna , Shchur Olha , Kochuiev Gennadii , Tymchenko Hanna
Published: May 2022

The aim: The aim was to study the relationships of IRS-1 gene polymorphism with indicators of the structural and functional state of the heart and blood vessels in patients with arterial hypertension under conditions of different metabolic comorbidity and body weight.
Materials and methods: We examined 340 patients with arterial hypertension with different body weight and different types of metabolic comorbidity and 30 healthy individuals aged 45-55. Anthropometric, Biochemical, Molecular genetic methods, Instrumental, Statistical methods were used.
Results: The presence of G/R + R/R genotypes in hypertensive patients with normal body weight was associated with an increase in intima-media thickness (CIMT), pulse wave velocity of carotid artery (cPWV) and lower endothelium-dependent vasodilatation (EDVD) compared with G/G genotype carriers. Hypertensive patients with obesity, carriers of G/R and R/R genotypes displayed more pronounced similar changes in vascular remodeling (higher CIMT, cPWV and lower EDVD) and as well as cardiac remodeling (larger sizes and left ventricular mass (LVM)) compared with G/G genotype carriers. Overweight carriers of the G/R + R/R genotypes were characterized by enlargement of LVM and its sizes, a higher CIMT indicator, but this effect was less than in the comorbidity of hypertension and obesity. In hypertensive patients with hypertension, obesity and type 2 diabetes mellitus, the presence of G/R + R/R genotypes was associated with an increase in left ventricular size, left ventricular mass index (LVMI) and CIMT.
Conclusions: The relationships of IRS-1 polymorphism with indicators of cardiovascular remodeling in hypertensive patients depending on body weight and the presence of various metabolic comorbidity have been established.
LEGAL OBLIGATIONS IN THE CONTEXT OF HUMAN ORGANS AND TISSUES TRANSPLANTATION
Authors: Popovych Tereziia P. , Potapchuk Anatoliy M. , Rogach Oleksandr Ya. , Dzhuhan Volodymyr V.
Published: May 2022

The aim: To highlight and analyze the nature of certain legal obligations occuring in the process of human organs and tissues transplantation, in particular, the following obligations: compliance with regulatory and medical requirements for organ and human tissues transplantation, obtaining the donor’s consent for organs and tissues transplantation, organs or tissues transplantation on a non-commercial basis. Materials and methods: Methodologically, this work is based on the system of methods, scientific approaches, techniques and principles with the help of which the realization of the research aim is carried out. There have been applied universal, general scientific and special legal methods. Conclusions: Analyzed regulatory and medical requirements, indicate the complexity of the transplant process, as well as the need for strict compliance with established regulations and rules. For the whole complex transplant procedure, one of the key points is the donor’s consent (disagreement) to remove anatomical materials from him. The obligation to perform organ or tissue transplantation on a non-commercial basis has a dual purpose: first, to prevent offenses and legal violations in this area; secondly, to determine as transparently and clearly as possible the list of costs incurred by the donor in connection with the organs and tissues removal and subject to reimbursement, the procedure for such reimbursement and its reasonable, acceptable and sufficient amount.
THE ROLE OF ADAPTIVE-STRESS RESPONSE IN THE PATHOGENESIS OF PERIODONTAL DISEASES
Authors: Pupin Taras I. , Honta Zoriana M. , Shylivskyy Ihor V. , Nemesh Oksana M. , Burda Khrystyna B.
Published: May 2022

The aim: The purpose of this work is to analyze the literature data of scientific research of Ukrainian and foreign scientists to assess the pathogenetic mechanisms of the adaptive stress response to the condition of periodontal tissues.
Materials and methods: Bibliosematic and analytical methods were used in the trial. The materials of the trial are international experience in studying the pathogenetic mechanisms of the interaction of psycho-emotional disorders and the development of periodontal lesions.
Conclusions: Chronic stress and depression suppress the immune system, cause the hormonal imbalances, lead to metabolic disorders in tissues and increase the risk of dystrophic and inflammatory processes in periodontal tissues, which in turn lead to reduced masticatory function, tooth loss, severe emotional instability and significant reduction in quality of life. Psycho-emotional disorders in patients slow down the treatment of inflammatory processes in periodontal tissues and contribute to the early recurrence. Thus, the problem of studying the adaptive stress response of the organism requires further research for deeply understaningits role in the etiology and pathogenesis of dental diseases and justify effective treatment and prevention measures for its correction.
Evaluation of Wellbore Stability by Analytical and Numerical Methods: A Case Study in a Carbonate Oil Field
Authors: Abazari Faramarz , Jalilifar Hossein , Riahi Mohammad Ali
Published: May 2022

The instability of the wellbore has significant effects on drilling, causing delays in operations, increasing costs, and ultimately may result in the abandonment of wells. Nowadays, it is possible to stabilize a wellbore by changing the drilling mud composition. With the help of rock mechanics and knowledge of the mechanical properties of the formation, the optimal path for the drilling of the well and the window of the mud is determined. Several features of the formation are influential in wellbore design; knowing these features is necessary for designing optimal mud weight to ensure wellbore stability. In practice, analytical methods for the calculation of the optimal mud weight are more convenient than numerical ones because the latter needs information on many samples that are usually unknown at the commencement of the project. This research investigates the wellbore stability in the Kupal carbonate oil field using an analytical method with three rock strength criteria of Mogi-Coulomb, Mohr-Coulomb, and Hoek-Brown failure. The authors conclude that the Mogi-Coulomb criterion predicts a minimum drilling mud pressure and is more conservative. This is due to the use of its intermediate stress.
The politico-geographical survey of contemporary world
Authors: Bína Jan
Published: May 2022

The article deals with political and state-juridical position of all countries in the world. First the international politico-geographical subjektivity of countries is discussed. Independent states are described as socialist countries, developed capitalist states and developing countries, divided according to their political or institutional system. A survey of administratively dependent countries in accordance with their official status is given.
Siyasal Pazarlama İletişiminde Yeni Sosyal Medya Kanallarının Kullanımın Z Kuşağı Üzerindeki Etkisini Belirlemeye Yönelik Betimleyici Bir Araştırma: Youtube ve Twitch Örneği
Authors: Aktepe Hilal Saadet , Durukan Tülin
Published: May 2022

Sosyal medyanın özellikle Z kuşağı için temel iletişim araçlarından biri hâline gelmiş olması, bu aracın pazarlama iletişiminde kullanımını yaygınlaştırmıştır. Siyasal pazarlama aracı olarak sosyal medya kullanımı ülkemiz için yakın bir geçmişe sahip olmakla birlikte, yaklaşan 2023 seçimleri için stratejik bir konumda yerini almıştır. Bu seçim, 1996 yılı sonrası doğan Z kuşağının oy kullanacağı ilk seçim olması bakımından partiler açısından özel ve kritik bir anlam taşımaktadır. Nitekim ürün ve hizmet pazarlamasında tüketiciler arası iletişimde Kotler tarafında “netandaşlık” kavramı ile ifade edilen sosyal ağlar benzeri yapı, siyasal parti ve liderlerin siyasal pazarlamaları içerisinde de kurulan ağlarla var olmaya başlamıştır. Bu yapı, Covid 19 pandemisi sürecinde hızla yaygınlaşmış ve Z kuşağı sınırlarını da aşarak toplum tabanına yayılmaya başlamıştır. Çevrimiçi topluluklar arası iletişim pandemi sürecinde Youtube canlı yayınları ile çevrimiçi oyun platformu olarak yayın hayatına başlayan Twitch canlı yayınları, ülkemizdeki siyasi liderlerin özellikle Z kuşağına doğrudan ulaştıkları kanallar olmuşlardır. Soru-cevap formatı ile yapılan canlı yayınlar, geleneksel medya kanalı ile kitlelere ulaşmada farklı bir yapıda ilerlemiştir. Bu betimleyici çalışma kapsamında, 2020-2021 yıllarında Türk siyasetçilerden Youtube ve Twitch yayını yapanların, yayın esnasında ve sonrasındaki sosyal medya etkileşimleri incelenerek siyasal pazarlamada bu yeni kanalların önemine vurgu yapılacaktır.
Social Enterprises and The Support for Entrepreneurs with Disabilities for an Inclusive Entrepreneurship Ecosystem: The Case of Turkey
Authors: Gül Özlem , Çelik Asiye Ayben
Published: May 2022

Persons with disability have the same rights and freedoms as everyone else, yet they have serious difficulties in gaining meaningful employment. Governments are responsible for ensuring social inclusion, accessibility, and equity for the disabled people in employment, but should also encourage them to establish enterprises which will empower them and contribute to their full economic participation.  Businesses generally target able-bodied consumers, even though disabled people as the untapped market, comprise around 15% of the world’s population. Social Enterprises (SE) prioritize social impact and social inclusion, but still require a profit contribution for the sustainability of the business. An SE providing inclusive and accessible products and services for disabled consumers can be run more successfully by a disabled entrepreneur who can internalize the disabled needs. Therefore, how disabled entrepreneurs are supported in their country will be a critical factor in their success. The research objective of this study is to reveal the supports provided in Turkey for disabled entrepreneurs in an inclusive entrepreneurial ecosystem. The findings show that support for entrepreneurship was available in financing, investment, education, R&D and consultancy provided by the state and NGOs. However, accessible support for disabled people was limited to İŞKUR and KOSGEB. Disabled entrepreneurs whose SE targeted disabled consumers were examined as good practice and it was concluded that such ventures should be encouraged, whilst NGOs, social entrepreneurship platforms and the state should strengthen the awareness and improve the accessibility of the opportunities and support available for disabled entrepreneurs.
All in the Details
Authors: Sankaran Neeraja
Published: May 2022

Peyton Rous’s reactions to his various colleagues offer a glimpse of the personality behind the scientist—and serve as a perfect example of the vital role archives play in the craft of history.
Bioactive phenolic compounds and organic acids in the decoction of fruits and leaves of Schinus areiraL
Authors:   Universidad Nacional de Misiones, Celaya Liliana S , Molina Ana C ,   Universidad Nacional de Jujuy, Gonzalez Maria A. ,   Universidad Nacional de Jujuy, Villa Walter C. ,   Universidad Nacional de Jujuy, Silva Luis R ,   Universidade da Beira Interior, Viturro Carmen I ,   Universidad Nacional de Jujuy
Published: May 2022

Leaf and fruit decoctions of Schinus areiraL. from northwest Argentina were investigated here. Phenolic compounds and organic acids were analyzed by HPLC. Antioxidant capacity and α-glucosidase inhibition were determined by using in vitrotests. The general toxicity was assessed against Artemia salinanauplii. Hyperoside and 3 O-caffeoylquinic acid in leaf decoctions; gallic acid and catechin in fruit decoction were the major phenolic compounds. Malic and citric acids were the main organic acid quantified in the leaf and fruit decoctions, respectively. Fruit decoction had a relatively important content of shikimic acid, precursor of Tamiflu. Leaf decoction presents a greater richness in bioactive compounds with antiradical activity against DPPH●, O2●-and ●NO radicals. S. areiraleaves and fruits had α-glucosidase inhibitory activity comparable to hyperoside and acarbose. Fruit decoction was not eco-toxic; leaf decoction showed significant eco-toxic activity and could be chosen for the search of other bioactive compounds with pharmacological activity.
Security of Energy Interests of Enterprises: Innovative Competencies of Personnel, Public Administration and Role of Exchange Trade
Authors: Ievgeniia Mishchuk , Olga Bondarchuk , Nataliia Riabykina , Yekateryna Riabykina , Petro Matkovskyi , Sergii Tkachenko , Oleksandra Rozhenko , Oksana Kornukh
Published: May 2022

The article proposes a methodology for assessing the state of security of energy interests of enterprises. In order to apply this methodology, security of energy interests is split into two components: security of energy efficiency and that of energy supply. Indicators and their corresponding liminal values are set for each of the components. A feature of the proposed assessment methodology is that it takes into account the speed at which actual security indicators can reach their liminal value. Application of the methodology allows us to conclude about the need for managerial intervention, decision-making and taking appropriate measures to improve security of energy interests as a whole and its individual components. The calculations conducted reveal that the actual indicators of energy supply security in 2018-2019 were equal to 1 at all mining enterprises of Ukraine. According to the value interpretation scale developed in the study, this value means that the state of security of energy supply was excellent (very high). In contrast, the state of energy efficiency security was not so stable and tended to deteriorate. The catastrophic state of energy efficiency security was detected at one of the mining enterprises under study, namely the PrJSC InGZK, in 2019, as the corresponding security indicator equaled zero. The obtained values of the state of security of energy efficiency are determinant for the general state of security of energy interests of the enterprises under study. In the article there are presented four directions to ensure security of energy interests of mining and metallurgical enterprises. The first direction provides for improvement of government regulation of the energy market. The second direction deals with reorientation of the production apparatus and introduction of resource-saving technologies that are to dramatically reduce energy and fuel intensity. The third direction involves more active participation in energy exchange trading. The fourth direction consists in attracting and training employees in new competencies and professions necessary for development, introduction and implementation of innovative energy-saving technologies at the enterprises and transition to an energy business model.
Joustavat äänestysmuodot pandemiavaalien pelastajana
Authors: Peltoniemi Johanna
Published: May 2022

Maailmanlaajuisen terveyskriisin jatkuessa valtiot ovat joutuneet tarjoamaan totutusta poikkeavia ratkaisuja vaalien järjestämiseen tai siirtämään niitä kokonaan. Koronapandemia on lisännyt tarvetta uudelleenarvioida äänestämisen helpottamiseen tähtääviä menetelmiä. Tämä puolestaan on nostanut ratkaistavaksi kysymyksen vaalikäytännöistä laajemminkin. Suurimmassa osassa koronapandemian aikana pidetyistä valtiollisista vaaleista äänestysaktiivisuus laski. Vaikka äänioikeutettujen äänestysaktiivisuus on eriytynyt myös normaalina aikana, tilanne on ollut aiempaa monimutkaisempi terveyskriisin aikana, jolloin vakavan koronan riskiryhmissä äänestysaktiivisuus laski suhteettomasti. Tarkastelun kohteena on ensimmäisen koronapandemiavuoden aikana (helmikuusta 2020 maaliskuuhun 2021) pidetyt kansalliset vaalit. Aineisto käsittää yhteensä 82 kansallista vaalia kaikkiaan 67 maassa. Keskeisimmät tutkimustulokset osoittavat, että pandemian aikana äänestysaktiivisuus laski, mutta toisaalta pandemia aiheutti dramaattisen muutoksen vaalien teknisessä järjestämisessä. Tärkeä muutos oli joustavien äänestysmenetelmien nopea yleistyminen. Pandemiavaalien aikana käytettyjen joustavien äänestysmenetelmien määrän ja äänestysaktiivisuuden muutoksen välinen yhteys on selvä. Mitä useampia joustavia äänestysmenetelmiä oli käytössä, sitä todennäköisempää oli, että äänestysprosentti pysyi samana tai jopa lisääntyi edellisistä vaaleista.
Uuden alku vai vanhan toisto?
Authors: Helimäki Theodora
Published: May 2022

Katsaus aluevaalien äänestämisestä.
Digitaalisia medioita, poliitikkojen kokemuksia ja vaaleja
Authors: Mäkinen Katja , Salo Miika
Published: May 2022

Pääkirjoitus 2/2022.
ВІДДІЛЕННЯ ВИЩОЇ ОСВІТИ НАПН УКРАЇНИ: НАУКОВІ ЗДОБУТКИ ТА СТРАТЕГІЧНІ ЦІЛІ
Authors: Saukh Petro , Nabok Mykola
Published: May 2022

Здійснено аналіз діяльності Відділення вищої освіти Національної академії педагогічних наук України, яка протягом всього періоду його існування спрямована на обґрунтування й науково-методологічний супровід модернізації вітчизняної системи вищої освіти на засадах світових досягнень та проривних практик освітнього й дослідницького простору. Окреслено основні стратегічні орієнтири та завдання, на вирішення яких скеровані основні зусилля членів Відділення та його установ. Розкрито найвагоміші досягнення наукових досліджень, які пов'язані з обґрунтуванням філософських засад модернізації вищої освіти, економіко-управлінських детермінант її розвитку; розбудовою системи державних стандартів вищої освіти на основі кваліфікаційних вимог і забезпечення відповідності змісту вищої освіти поточним і стратегічним цілям країни; підвищенням якості освіти в контексті євроінтеграції, урізноманітнення типів і форм надання освітніх послуг з урахуванням тенденцій розвитку та потреб сучасного ринку праці; впровадженням інноваційних технологій і дистанційного навчання, нових підходів SMART-спеціалізації та Індустрії 4,0 в освітні програми; інтернаціоналізацією науково-освітнього процесу тощо. Акцентовано на стратегічних цілях і завданнях Відділення, які мають бути вирішеними в короткостроковій та середньостроковій перспективі. Зокрема це стосується практико-орієнтованих досліджень, пов'язаних із розробленням моделей і конкретних механізмів оптимізації мережі закладів вищої освіти, руху до університетів світового класу; побудови ефективної системи інтеграції вищої освіти, науки та виробництва, національного виховання й соціалізації студентської молоді; науковим обґрунтуванням концепції інтернаціоналізації вищої освіти як важливого фактору її конкурентоспроможності в умовах ситуації із загостренням тощо.