bluuebunny/crossref_metadata_2025 huggingface dataset:
Targeted drugs in the treatment of acute myeloid leukemia in children
Authors: Seregin G. Z. , Lifshits A. V. , Valiev T. T.
Published: September 2020

The recent chemotherapeutic approaches to acute myeloid leukemia (AML) management reached the limits, achieving overall survival rate of approximately 70 %. An intensification of chemotherapeutic regimens is barely possible due to high level of toxicity and risk of lifethreatening complications. The modernization of program therapy of AML involves the clinical application of achievements in molecular biology, immunology and cytogenetic of the tumor cell. The researches in fundamental oncology revealed the phases of leukemogenesis and defined selective ways of targeted therapy in the treatment of AML.
Thrombotic microangiopathy associated with hematopoietic stem cell transplantation: general characteristics and an example from clinical practice
Authors: Machneva E. B. , Bolokhonova M. A. , Aliev T. Z. , Shevtsov D. V. , Suleymanova A. M. , Sidorova N. V. , Osmanov E. A. , Kirgizov K. I.
Published: September 2020

Associated hematopoietic stem cell transplantation (HSCT) or transplant-associated thrombotic microangiopathy (TA-TMA) is currently a generally recognized and severe complication of HSCT with a high risk of mortality. TMA is characterized by microangiopathic hemolytic anemia and thrombocytopenia, resulting in the accumulation of platelets in the microvasculature, which leads to dysfunction of the ischemic organ. The pathogenesis of TА-TMA is based on endothelial damage by various trigger factors (in particular, chemotherapeutic agents in the conditioning regimen, the use of calcineurin inhibitors, alloreactivity, infectious agents). The article presents the peculiarities of terminology, pathogenesis and clinical manifestations of TA-TMA, methods of therapy for this pathology. Examples of management of patients with TA-TMA are demonstrated using a clinical example.
Mass Spectrometry Techniques: Principles and Practices for Quantitative Proteomics
Authors: Rotello Rocco J. , Veenstra Timothy D.
Published: September 2020

:

In the current omics-age of research, major developments have been made in technologies
that attempt to survey the entire repertoire of genes, transcripts, proteins, and metabolites present
within a cell. While genomics has led to a dramatic increase in our understanding of such
things as disease morphology and how organisms respond to medications, it is critical to obtain information
at the proteome level since proteins carry out most of the functions within the cell. The
primary tool for obtaining proteome-wide information on proteins within the cell is mass spectrometry
(MS). While it has historically been associated with the protein identification, developments
over the past couple of decades have made MS a robust technology for protein quantitation
as well. Identifying quantitative changes in proteomes is complicated by its dynamic nature and the
inability of any technique to guarantee complete coverage of every protein within a proteome sample.
Fortunately, the combined development of sample preparation and MS methods have made it
capable of quantitatively comparing many thousands of proteins obtained from cells and organisms.
Anti-BVDV Activity Evaluation of Naphthoimidazole Derivatives Compared with Parental Imidazoquinoline Compounds
Authors: Ibba Roberta , Piras Sandra , Delogu Ilenia , Loddo Roberta , Carta Antonio
Published: September 2020

Background:

Pestivirus genus includes animal pathogens which are involved in economic impact for the livestock industry. Among others, Bovine Viral Diarrhoea Virus (BVDV) establish a persistent infection in cattle causing a long list of symptoms and a high mortality rate. In the last decades, we synthesised and reported a certain number of anti-BVDV compounds.

Methods:

In them, imidazoquinoline derivatives turned out as the most active. Their mechanism of actions has been deeply investigated, BVDV RNA-dependent RNA polymerase (RpRd) resulted as target and the way of binding was predicted in silico through three main H-bond interaction with the target.

The prediction could be confirmed by target or ligand mutation. The first approach has already been performed and published confirming the in silico prediction.

Results:

Here, we present how the ligand chemical modification affects the anti-BVDV activity. The designed compounds were synthesised and tested against BVDV as in silico assay negative control.

Conclusion:

The antiviral results confirmed the predicted mechanism of action, as the newly synthesised compounds resulted not active in the in vitro BVDV infection inhibition.
A Case Report: Type II Abernethy Malformation Complicated with Congenital Polydactyly and Enlargement of all Cardiac Chambers
Authors: Zhu Cheng , Wang Min , Hao Qian
Published: September 2020

Background:

Abernethy malformation is a kind of congenital malformation of the portal vein system caused by abnormal portacaval shunts. It can be in combination with many other congenital malformations. There has been a limited number of patients since the first patient was reported, leading to limited knowledge of this kind of disease.

Methods:

In August 2018, we treated a patient diagnosed with type II Abernethy malformation complicated with both congenital polydactyly and enlargement of all cardiac chambers, which is extremely rare and can be supplementary to the existing cases. According to a comprehensive and adequate assessment of patients' condition, we treated him with oral silybin (70 mg every time and 3 times a day) for 3 months, and advised him to make follow-up visits.

Results:

At the latest follow-up, we knew the health condition of this patient was generally satisfactory, whether in terms of laboratory test results or his daily life experience.

Conclusion:

Although the major therapy for Abernethy malformation is surgery, this case suggests that simple conservative treatment with regular follow-up visits can be suitable for certain patients.
Dental Patient Management in the Context of the COVID-19 Pandemic: Current Literature Mini-Review
Authors: Horzov L. , Goncharuk-Khomyn M. , Kostenko Y. , Melnyk V.
Published: September 2020

Background:

Considering dental data gain associated with COVID-19 in the last few months of 2020, it is highly important to provide an assertive critical literature review with the categorization and systematization of available findings.

Objective:

The purpose of this article is to shed light on the concerns of dentists who provide treatment of children and adults during the pandemic of COVID-19.

Methods:

The search for relevant publications related to the objective topic was done via the Google Scholar engine with the use of next keywords: “dentistry”, “coronavirus”, “COVID-19”, “dental treatment”. All collected articles were processed using content-analysis principles with further systematization and categorization of obtained data in Microsoft Excel 2019 software (Microsoft Office, 2019).

Results:

Overview of trans-national guidelines considering COVID-19 prevention within dental care conditions could be categorized into the next few aspects: elective pattern of dental care, postpone dental treatment, screening algorithms through telecommunication and use of specialized PPE. Under the emergency mode of dental care, there are three basic P’s that should be considered during every dental procedure: patient’s self-care, prophylaxis and prioritization of pathology elimination approaches.

Conclusion:

Dentists should be fully informed and supported with CDC and WHO guidelines and recommendations, but also with national and regional legislation act related to control of dental care provision during COVID-19 epidemy. Changes in the general dental practice during the post-COVID era are inevitable, but those represent normal development and recovery of the dental field after pandemic mode.
The Feasibility and Applications of Non-invasive Cardiac Monitoring in Obese Patients Undergoing Day-case Surgery: Results of a Prospective Observational Study
Authors: Sansone P. , Giaccari L.G. , Colella U. , Coppolino F. , Pace M.C. , Passavanti M.B. , Pota V. , Aurilio C.
Published: September 2020

Aims:

This prospective observational study evaluates the utility of non-invasive cardiac monitoring in obese patients in the day-surgery case, considering factors, such as Body Mass Index (BMI) and anaesthesia technique.

Background:

Obese patients are more likely to be admitted to hospital or to get hospitalized because they are more prone to concomitant diseases and obesity itself is not a contraindication to day surgery. Obese patients are a high-risk patient population that may particularly benefit from monitoring perioperative haemodynamic variations.

Methods:

In this observational study, we compared haemodynamic variations between overweight or obese and normal weight patients undergoing day-case surgery. We adopted NICOM® as a non-invasive cardiac output monitoring.

Objective:

The aim of the current study was to investigate the haemodynamic impact of BMI and anaesthesia technique during day-case surgery procedures. The other goal was to evaluate the feasibility and applications of non-invasive cardiac output monitoring among the obese population in day-surgery.

Results:

74 patients were included in the study. 34 were overweight or obese (weight 84 ± 10 kg, height 160 ± 10 cm, BMI ≈ 30 kg/m2), 40 were normal weight (weight 63 ± 15 kg, height 160 ± 10 cm, BMI ≈ 22 kg/m2). Compared to normal-weight patients, obese patients show an increase in blood pressure with a return to baseline values at the end of surgery (p < 0.05). The Cardiac Output (CO) shows a similar trend, whereas the heart rate is normal. A decrease in the Cardiac Index (CI) during the operation was noticed in both groups, the one in obese patients (p = 0.24) being greater. In the same way, the Stroke Volume Index (SVI) was lower in obese patients during surgery (p < 0.05). In spinal anaesthesia, the Total Peripheral Resistance Index (TPRI) was not statistically different between the groups of study. As for the TPRI in obese patients, we reported values similar to the ones in non-obese patients in spinal anaesthesia. In local anesthesia, TPRI was higher in obese patients than in non-obese.

Conclusion:

Cardiovascular alterations in relation to obesity include an increase in blood pressure, CO and SV. An inadequate monitoring of haemodynamic parameters is a risk factor for perioperative complications. NICOM® provides a continuous, non-invasive haemodynamic measurement.
O que as personaxes len
Authors: Janeiro Patricia A.
Published: September 2020

A literatura está presente na ficción televisiva a través das adaptacións, pero as obras literarias tamén se amosan de forma directa na pantalla, ben como homenaxe ás fontes das que beben os creadores, para establecer a atmósfera dun episodio ou dun arco argumental, ou cun fin didáctico.

Mediante a análise dalgúns exemplos, este artigo tentará profundar na relación simbiótica entre ambos medios e demostrar que esta intermedialidade non só é enriquecedora para a serie televisiva, senón que tamén dota de nova vida as obras literarias que esta amosa.
Antonio J. Gil González & Pedro Javier Pardo (eds.). Adaptación 2.0. Estudios comparados sobre intermedialidad
Authors: Sanchis M. Dolores Lerma
Published: September 2020

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Looking for Sin in All the Wrong Places: An Empirical Investigation of the Affluenza Construct
Authors: Lorenzi Peter , Zhang Jason Q. , Friedmann Roberto
Published: September 2020

Sin taxes, popular source of tax revenue, are best applied to antisocial and inelasti

consumption. But what consumption behaviors are antisocial and addictive? This research examines the assumption that excessive antisocial consumption – affluenza – is addictive. Four hundred fourteen subjects completed a measure of affluenza. Analysis identified six factors: materialism, overspending, urgency, financial stress, shopaholicism, and self-centeredness. The results showed little evidence of the hypothesized level of affluenza in the American working population, with some limited impact of age, gender and education. Politicians looking for sins to tax may be looking in all the wrong places.
Exploring the Factors Affecting the Use of Kiasu Tactics
Authors: Kirby Eric G. , Kirby Susan L. , Bell James D. , Schafer Curt
Published: September 2020

Kiasuism is an excessive form of competitiveness in which an individual tries to get the most out of every interaction. It manifests itself in the form of positive and negative tactics. This study explores the factors affecting the use of kiasu tactics. Maximization, conscientiousness, and perceptions of distributive justice are examined using multiple regression analysis. Maximizers are far more likely to engage in both kiasu positive and kiasu negative tactics than are satisficers. When people perceive that outputs are distributed fairly, they are more likely to engage in kiasu positive tactics. Conscientiousness did not have a significant effect.
Controlling the Sense of Embodiment for Virtual Avatar Applications: Methods and Empirical Study (Preprint)
Authors: Kim Chang-Seop , Jung Myeongul , Kim So-Yeon , Kim Kwanguk
Published: September 2020

BACKGROUND

The sense of embodiment (SoE) is the feeling of one’s own body, and research on the SoE extends from the rubber hand illusion to the full-body ownership illusion with a virtual avatar.

OBJECTIVE

The key to utilizing a virtual avatar is understanding and controlling the SoE, and it can be extended to several medical applications. In this study, we aimed to clarify these aspects by considering the following three subcomponents of SoE: sense of agency, ownership, and self-location.

METHODS

We defined a human avatar (HA), point light avatar (PLA), and out-of-body point light avatar (OBPLA) and compared them in three user studies. In study 1, 28 participants were recruited and the three avatar conditions (HA, PLA, and OBPLA) were compared. In study 2, 29 new participants were recruited, and there were two avatar conditions (HA ad PLA) and two motion synchrony conditions (synchrony and asynchrony). In study 3, 29 other participants were recruited, and there were two avatar conditions (PLA and OBPLA) and two motion synchrony conditions (synchrony and asynchrony). Dependent measures included sense of agency, ownership, and self-location; emotional response; presence; and simulator sickness.

RESULTS

The findings of study 1 showed that the three avatar generation methodologies can control the sense of ownership and self-location in a stepwise manner while maintaining a high sense of agency. In studies 2 and 3, we found dependencies among the three subcomponents of SoE and observed that they affected users’ subjective experiences.

CONCLUSIONS

Our findings may have implications for boosting the effects of virtual avatar applications in medical areas, by understanding and controlling the SoE with a full-body illusion.
Soewardi di Pengasingan: Nasionalisme versus Sosialisme
Authors: Wibisono Joss
Published: September 2020

Right from the start of his banishment to the Netherlands in fall 1913, Soewardi Suryaningrat had been trying to make the Dutch colonial government revoke this decision. For this he approached the social democrats that were actually in the opposition. But to no avail, and Soewardi became disillusioned with the social democrats. Analysing his conﬂict with the left makes clear in which direction Soewardi’s nationalism was heading. Was he just an “early Javanese-Indonesian nationalist”, or is there more to say about his brand of nationalism?
Akar-akar Kanan daripada Nasionalisme Indonesia: Nasionalisme Jawa dalam Konteks Kesejarahannya
Authors: Fakih Farabi
Published: September 2020

This papers explores the thoughts of Javanese nationalists during the early phase of Indonesian nationalism. It will specifcally look into the ideas of Tjipto Mangoenkoesoemo and Noto Soeroto as prototypes of new nationalist sentiments that grew during a period of intense revolutionary fervor, marked by the rise of marxism and fascism throughout the world. By looking at these factors, it wants to situate the global roots of Indonesian nationalism and contextualize Indonesian nationalist history within the global development of the early twentieth century.
Editorial. Avances de la ciencia y perspectivas de las personas infectadas por el VIH en Venezuela
Authors: Chacín-Bonilla Leonor
Published: September 2020

Editorial.
Efecto del 2-aminoindano rígido, derivado del acenafteno, sobre la conducta estereotipada de ratas. Papel del sistema dopaminérgico cerebral
Authors: Vera Mariagracia , Angel Ligia , Rodríguez Lucía , Cáceres Ana , Ortega José , Charris Jaime , Israel Anita , Garrido María , López Simón , Migliore Biagina , Ramírez María , Angel Jorge
Published: September 2020

Las enfermedades neurodegenerativas y neuropsiquiátricas se encuentran directamente relacionadas con alteraciones o disfuncionalidad delsistema dopaminérgico central. Entre las primeras encontramos la enfermedad de Parkinson (EP), la disquinesia tardía, el síndrome de Tourette, la Corea de Huntington (EH), y entre las segundas la Esquizofrenia (EZ), la adicción, la manía,la depresión, y los desórdenes de la alimentación. Con el fin de contribuir con el arsenal terapéutico que permita restaurar la homeostasis de la neurotransmisión dopaminérgica central, se evaluó farmacológicamente el clorhidratodel 1-amino-6,7,8,8a-tetrahidroacenafteno 2 (Ja116a) mediante la cuantificación de sus efectos sobre la conducta estereotipada de ratas. Se emplearon ratas machos de la cepa Sprague-Dawley, a las que se les implantó una cánula intracerebroventricular (ICV). El compuesto 2 (Ja116a) fue administrado porvía ICV (5μg/5μL y 50μg/5μL), en presencia o ausencia de apomorfina (APO),haloperidol (HAL), buspirona (BUS) o ziprasidona (ZIP); o por vía intraperitoneal(IP) (1mg/Kg) en ratas tratadas con APO o HAL. Igualmente, un grupo de ratas fue sometido a denervación dopaminérgica central mediante la 6OH-dopamina(6OHDA). Los resultados mostraron que Ja116a induce una conducta estereotipada de roídas y olfateos (sistema extrapiramidal) y acicalamientos y lamidas (sistema límbico), efectos que fueron bloqueados por el HAL y reducidospor la buspirona y la 6OHDA. Estos hallazgos indican que Ja116 actúa principalmente como un agonista dopaminérgico postsináptico, por lo que podría proponerse como un fármaco novedoso para el tratamiento de enfermedades neurodegenerativas tales como la Enfermedad de Parkinson.
Application of CORE Learning to Improve Mathematical Connection Capabilities and Self-Efficacy
Authors: Ramadhani Eka Yanuar , Kusuma Anggun Badu
Published: September 2020

The study aimed to improve the skills of students mathematical connections and self-efficacy for grade VII D of SMP N 3 Sidareja in the 2018/2019 academic year through CORE (Connecting, Organizing, Reflecting, and Extending) learning on the topic of triangles and rectangles. The study was conducted in three cycles and each cycle consisted of planning, action, observation, evaluation, and reflection stages. The instrument used was a description test to measure the skills of students' mathematical connections given at the end of each cycle, while the instrument used to measure self-efficacy was self-efficacy questionnaire. Based on the findings, each cycle obtained an improvement. The first cycle obtained mathematical connection skills by an average of 64.74, 77.24 in the second cycle, and 81.41 in the third cycle. The average results of students self-efficacy in grade VII D in the first the cycle was 69.67, 76.05 in the second cycle, and 79.85 in the third cycle. Based on the data above, it can be drawn that there was an improvement of students' mathematical connection skills and self-efficacy from cycle I to cycle II and from cycle II to cycle III through CORE learning (Connecting, Organizing, Reflecting, and Extending).
Improvement of Mathematics Learning Outcomes by Applying The Missouri Mathematics Project Learning Model And Dienes Game Theory
Authors: Fakhri Muhammad , Taufik Marhan , Ismail Agung Deddiliawan
Published: September 2020

Based on the results of first observations and interviews with class teachers at SMP Negeri 06 Batu, mathematics learning outcomes for class VIIA students in the End Semester Test (EST) even semester of the 2018/2019 school year had an average grade below the Minimum Criteria of Mastery Learning (MCML) and only about 5 students reached MCML. This research aims to improve the mathematics learning outcomes of Grade VIII A students by applied the Missouri Mathematics Project (MMP) learning model combined with Dienes Game Theory. This research method used the Classroom Action Research (CAR) method with application for 4 meetings in 2 cycles. Each cycle there are 4 stages: planning, implementing, observing, and reflecting. Data collection techniques used tests, interviews, observations, and document studies. Data collection techniques used were tests, interviews, observations, and document studies. The results showed that by applying the MMP learning model combined with Dienes Games Theory, it could improve mathematics learning outcomes for students of class VIII A. The results of EST grade VII A students as the initial reference were 73,8, to 84.8 in cycle 1, and 86 .0 in cycle 2.
The Effect of REACT Model Assisted Fable-Math Book Media on Mathematical Problem Solving Of Elementary School Students
Authors: Arfiani Destiana Dian , Ulya Himmatul , Wanabuliandari Savitri
Published: September 2020

This study aims to analyze (1) the average mathematical problem solving ability of students who can achieve the KKM, (2) the proportion of students who can complete classical completeness of 75%, (3) differences in students' mathematical problem solving abilities before and after the REACT model assisted by fable-math book media is applied, (4) increasing mathematical problem solving abilities. The research method used is quantitative research with a pre-experimental design trial design in the form of one group pretest posttest. Sampling was done by means of purposive sample. The sample in this study were IV grade students in academic year 2019/2020. Collecting data using interview techniques, documentation, and tests. The data that has been collected is then analyzed using statistical analysis in the form of one sample t-test, z-proportion test, paired sample t-test, and n-gain test. After applying the REACT model assisted by the fable-math book media the results of the study showed that the average score of the student's problem-solving ability test got more than 70, the proportion of students who completed the test could achieve classical completeness above 75%, there were significant differences in the pretest and posttest results, and there is an increase in students' mathematical problem solving abilities with the medium category.
Analysis of Mathematical Communication Capabilities in Completing Problems in Matrix Materials Based on Solo Taxonomy
Authors: Setyowati Sulis , Cholily Yus Mochamad , Azmi Rizal Dian
Published: September 2020

The purpose of this study is to describe the mathematical communication skills based on SOLO Taxonomy in students of class XI of Mathematics and Natural Sciences Muhammadiyah 3 Batu in solving problems on matrix material. This type of research is descriptive qualitative, where the subject is 17 students of class XI MIPA. The method of collecting research data uses test instruments. Based on the results of data analysis, it can be concluded thatas many as 4 students with very good mathematical communication skills criteria, 6 students with good mathematical communication skills criteria, 7 students with sufficient mathematical communication ability criteria and students. Whereas for students with written mathematical communication skills criteria lacking none. Students are in very good criteria, able to solve Unistructural - Relational level problems in SOLO Taxonomy. Meanwhile, students with good written mathematical communication skills are able to solve Unistructural level questions and Multistructural levels in SOLO Taxonomy. Then students with written mathematical communication ability criteria are quite capable of solving Unistructural level problems in SOLO Taxonomy.The average of written mathematical communication skills is in good criteria with the average value of written mathematical communication skills, namely 61.95, so that the average student is able to solve problems at a level Unistructural - Multistructural on SOLO Taxonomy.
Comunicação conjugal negativa e aberta: modelo interdependente de efeito ator/parceiro no ajustamento conjugal
Authors: Batista da Costa Crístofer , Pereira Mosmann Clarisse
Published: September 2020

A comunicação é imprescindível à avaliação e intervenção em psicoterapia conjugal. Nesse sentido, foi investigado se a comunicação conjugal negativa e aberta impactam no ajustamento conjugal de casais heterossexuais. Trata-se de um estudo quantitativo, transversal, correlacional e explicativo. Foram avaliados 231 casais residentes no Sul do Brasil. Os participantes responderam o Communication Questionnaire e o Revised Dyadic Adjustment Scale R-DAS. Os dados foram analisados de forma diádica por meio do Actor Partner Interdependence Model - APIM e indicaram que a comunicação negativa provoca impacto superior à comunicação aberta no ajustamento conjugal de maridos e esposas, já que provocou efeitos ator e parceiro. A comunicação aberta provocou somente o efeito ator para maridos e esposas. Os resultados foram discutidos à luz da literatura científica considerando as possíveis implicações para a área clínica e para a pesquisa.
What “the Semantic Sieve” Determines in the Process of Translation
Authors: Boasiako Albert Antwi
Published: September 2020

Semantics is meaning communicated through language (Saeed I.J.). Semantics is the study of relationship between words and their meanings; it is directly linked with the conceptual meaning of words, and the associative meaning. Semantic sieve as a concept is an innovative phenomenon. This linguistic phenomenon is a process whereby a word is dispersed through a semantic tunnel which in some cases produces different meaning. This is explained through different models. The semantic sieve is related to translation, where the deep structure of words differs from the surface structure. There are some concepts and words in Akan and English that are absent in Russian, others are known in Akan but virtually absent in the English language.
Chinese Insertions Functioning in English: A Comparative Approach to Fiction and Non-Fiction Texts
Authors: Lupachyova Tatiana A. , Bereznitskaya Viktoriya V.
Published: September 2020

The present article is devoted to the comparative analysis of Chinese insertions functioning in fiction and non-fiction written in English based on the works of Amy Tan and Peter Hessler. As the research showed, the leading function of insertions in non-fiction was documentary function, whereas in fiction it was the function of ethnic coloring and the function of hero speech characteristics. The functions in the analyzed texts overlap and complement one another. Structurally the insertions in non-fiction feature words and phrases, in fiction they vary from interjections to significant parts of texts.
Motives of Home and Homelessness in the Novel by F.M. Dostoevsky “The Brothers Karamazov”
Authors: Yeleussizova Meruert B.
Published: September 2020

The article is devoted to the study of the complex motive home-antidome in the work of F. Dostoevsky The Brothers Karamazov. Studying the motive as a key unit of narratology, the author comes to the conclusion that in Dostoevskys poetry a special role is played by antinomic motives, the multidirectional semantic potential of which contributes to the complexity of the poetic dialectic of the writer. Thus, the motive of the home in Dostoevskys novel is inextricably linked with the motives of homelessness, wandering, the search for the place in the world by the heroes of the novel. Each of the heroes of the novel is a bearer of the motive function of home. The image of old Karamazov is associated with the idea of desacralizing the house as an intimate, family space. Each of the brothers is in a transit situation, not having, according to the thesis of Yu.M. Lotman, fastening to a certain topos. Homelessness becomes for heroes of the work the starting point of a spiritual search. Using the methods of linguistic-poetic and literary analysis, the author of the article concludes that the motives of the anti-home in the Brothers Karamazov novelty explicate the writers idea of a person and his place in the world, and in a broader sense, of the past and future of Russia, which has lost touch with previous generations and faith in God.
The Effect of Heating Schedule on Physico-Chemical Properties of Instant Coffee of Liberika Tungkal Jambi
Authors: Mursalin Mursalin , Nizori Addion , Rahmayani Irma
Published: September 2020

Abstract— The making of instant brewed coffee using co-crystallization method is strongly influenced by the heating schedule (HS) applied. Five levels of HS (HS1, HS2, HS3, HS4 and HS5) were studied on the physico-chemical properties of instant coffee of Liberika Tungkal Jambi. The treatment was applied in a completely randomized design with 4 replications. The coffee was extracted using a special coffee extractor in a ratio of hot water/coffee powder of 15/1. Parameters observed were moisture content, ash content, pH, solubility, and total dissolved solids. The data obtained were analyzed using ANOVA and DNMRT at 5% significance. The results showed that the physico-chemical properties of instant coffee had significant effect on moisture content, pH, solubility, and total dissolved solids but not on ash content. The optimal HS to produce Liberika Tungkal Jambi instant coffee with good quality was heating at 110oC in the beginning, followed by 90oC at the initiation of crystallization, and 75oC when crystal growth (HS3).  HS3 produces instant coffee with water content 1.57-1.61%; ash content 6.12-6.16; pH 5.50-5.56; solubility 98.22-98.25; and total dissolved solids 8.47-8.53% Brix.

 

Keywords— crystal growth,instant coffee, libtukom, recrystallization,
STRATEGI VISUAL PADA INFOGRAFIS AQUA RAMADHAN 242 (HARMONISASI PARADOKS VISUAL PADA PENGGUNAAN 2 GAYA DESAIN)
Authors: Aswan Rifki
Published: September 2020

Infographics can reduce the use of words that are not needed and can package messages to become more interesting. Research on Aqua 242 infographics of Ramadhan uses a qualitative method with a case study approach to identify the appropriateness of health infographic principles and visual strategies in the paradoxical visual style applied by the Ramadhan AQUA 242 campaign infographics. To find out the visual strategy adopted by the Y&R design team in overcoming the problem. Fill in the summary.
Teaching engaged ethnography and socio-cultural change: Participating in an urban movement in Thessaloniki, Greece.
Authors: Deltsou Eleftheria
Published: September 2020

How can ethnographic research be taught? What kinds of ethnographic environments are involved in the study of contemporary socio-cultural issues? How / where can socio-cultural change be spotted? Where do ethnographic reflexivity and engaged ethnography stand with regard to comprehending and furthering socio-cultural change? Can/should ethnographic work fully conflate with critical activism? Can the teaching of engaged ethnographic research instigate critical awareness of the researcher’s positionality-ies? Considerations of the above questions will be endeavored via the participation of the author in an urban movement in Thessaloniki, Greece. Her double engagement as resident and academic teacher will expose the interrelatedness of these issues and the methodological, epistemological, and political implications that engaged ethnography raises.
Media Sovereignty and Digital Activism
Authors: Zanotti Laura , Soares da Silveira Diego , Kaitlin Harris
Published: September 2020

This article describes and analyses a collaborative project that combines service-learning and community engagement (SLCE) objectives and goals with anthropological commitments to support an Indigenous filmmaking collective media centre in one Mẽbêngôkre-Kayapó community, Brazil. We adapted curricular designs already in place in SLCE semester-long or summer abroad programs to incorporate decolonizing methodologies and symmetrical anthropological approaches to co-create media centre design recommendations for community partners. We designed the project to provide opportunities in which partners could critically engage with histories of mis/representation of Indigenous Peoples, dialogically learn about diverse cultural worldviews and ontologies, and confront stereotypes that are commonly associated with Indigenous Peoples engagement with technologies. We discuss how this work influenced how initial design recommendations for the media centre and collective. We conclude by reflecting on this projects’ approach to community-based projects and the synergistic outcomes and tensions that can result from co-creating transdisciplinary projects centred on addressing sovereignty and activism. Finally, we suggest that supporting digital activism and media sovereignty relies on fortifying relational networks of collaboration and respect.
Red Fox (Vulpes vulpes) scavenging on the spring sea ice: potential implications for Arctic food webs
Authors: Jung Thomas S. , Suitor Michael J. , Barykuk Steven , Nuyaviak Joseph , Gordon Danny C. , Gordon, Jr. Danny , Pokiak Ernest
Published: September 2020

Red Fox (Vulpes vulpes) has been increasingly observed in the Arctic. However, few observations of Red Foxes occupying and using resources on the sea ice have been reported. We observed a Red Fox scavenging on a Polar Bear (Ursus maritimus) carcass on the Beaufort Sea, Northwest Territories, Canada. The fox was in a jumble of ice (i.e., rubble ice) approximately 4.5 km from shore. Local Inuvialuit hunters had also previously observed Red Foxes on the sea ice. Our observation, coupled with those of Inuvialuit hunters, is of interest because it provides additional information on the adaptability of Red Foxes to local environments and their ability to use a wide range of habitats and food sources. Moreover, it points to encroachment by Red Foxes into the offshore habitat of Arctic Foxes (Vulpes lagopus) and potential competition with them for scarce resources, which may impact trophic food webs.
First confirmed nest of Long-billed Curlew (Numenius americanus) in roadside brush stubble
Authors: Sorenson Graham H. , Hollyoake Alyssa L. , Bradley David W.
Published: September 2020

Long-billed Curlew (Numenius americanus) typically nests in open grass habitat, such as native grassland, hayfields, or cow pasture. In May 2019, we discovered a Long-billed Curlew nest in the dense roadside shrub stubble near Prince George, British Columbia. The shrub stubble substrate for this nest appeared to be taller and denser than adjacent hayfields, which reduced the visibility of the nest site. The eggs in this nest were the first to hatch of the 11 curlew nests we monitored in the area.
The Effect of Compensation Caps on Risk-Taking
Authors: Kreilkamp Niklas , Matanovic Sascha , Sommer Friedrich , Wöhrmann Arnt
Published: September 2020

Using an experiment, we investigate the joint effects of compensation caps and formal justification requirements on risk-taking. Compensation caps restrict the earnings potential of decision-makers and have been implemented to influence risk-taking behavior, especially after the financial crisis. Rational choice theory predicts that caps should restrict only risk-seeking decision-makers from taking undesired risk and not affect risk-averse decision-makers. Based on the compromise effect, however, we predict that compensation caps will also affect risk-averse decision-makers. Moreover, we posit that the effect of compensation caps on risk-averse decision-makers is stronger under high justification pressure. Our results support both hypotheses and indicate unintended consequences of compensation caps. In particular, risk-averse decision-makers also take less risk when their compensation is capped, especially in combination with justification requirements. The result might be dysfunctionally low levels of risk-taking for exploiting entrepreneurial opportunities.

JEL Classifications: M12; M41; M52.
Cognitive Function Following Diabetic Ketoacidosis in Children With New-Onset or Previously Diagnosed Type 1 Diabetes
Authors: Ghetti Simona , Kuppermann Nathan , Rewers Arleta , Myers Sage R. , Schunk Jeff E. , Stoner Michael J. , Garro Aris , Quayle Kimberly S. , Brown Kathleen M. , Trainor Jennifer L. , Tzimenatos Leah , DePiero Andrew D. , McManemy Julie K. , Nigrovic Lise E. , Kwok Maria Y. , Perry Clinton S. , Olsen Cody S. , Casper T. Charles , Glaser Nicole S.
Published: September 2020

OBJECTIVE

This study assessed whether a single diabetic ketoacidosis (DKA) episode is associated with cognitive declines in children with newly diagnosed type 1 diabetes and whether the same is true in children who had previously been diagnosed after accounting for variations in glycemic control and other relevant factors.

RESEARCH DESIGN AND METHODS

We prospectively enrolled 758 children, 6–18 years old, who presented with DKA in a randomized multisite clinical trial evaluating intravenous fluid protocols for DKA treatment. DKA was moderate/severe in 430 children and mild in 328 children. A total of 392 children with DKA had new onset of type 1 diabetes, and the rest were previously diagnosed. Neurocognitive assessment occurred 2–6 months after the DKA episode. A comparison group of 376 children with type 1 diabetes, but no DKA exposure, was also enrolled.

RESULTS

Among all patients, moderate/severe DKA was associated with lower intelligence quotient (IQ) (β = −0.12, P < 0.001), item-color recall (β = −0.08, P = 0.010), and forward digit span (β = −0.06, P = 0.04). Among newly diagnosed patients, moderate/severe DKA was associated with lower item-color recall (β = −0.08, P = 0.04). Among previously diagnosed patients, repeated DKA exposure and higher HbA1c were independently associated with lower IQ (β = −0.10 and β = −0.09, respectively, P < 0.01) and higher HbA1c was associated with lower item-color recall (β = −0.10, P = 0.007) after hypoglycemia, diabetes duration, and socioeconomic status were accounted for.

CONCLUSIONS

A single DKA episode is associated with subtle memory declines soon after type 1 diabetes diagnosis. Sizable IQ declines are detectable in children with known diabetes, suggesting that DKA effects may be exacerbated in children with chronic exposure to hyperglycemia.
Incidence of Hospitalization for Heart Failure Relative to Major Atherosclerotic Events in Type 2 Diabetes: A Meta-analysis of Cardiovascular Outcomes Trials
Authors: Sacre Julian W. , Magliano Dianna J. , Shaw Jonathan E.
Published: September 2020

BACKGROUND

Emerging evidence points to heart failure as being a common first presentation of cardiovascular (CV) disease in type 2 diabetes.

PURPOSE

The purpose of this study was to determine whether hospitalization for heart failure (HHF) occurs more or less frequently than major adverse CV events (MACE) in people with type 2 diabetes.

DATA SOURCES

Placebo arms of CV outcomes trials in type 2 diabetes were included.

STUDY SELECTION

Sixteen CV outcomes trials were selected, including five dipeptidyl peptidase 4 inhibitor trials, seven glucagon-like peptide 1 receptor agonist trials, and four sodium–glucose cotransporter 2 inhibitor trials.

DATA EXTRACTION

We extracted incidence rates of HHF, myocardial infarction (MI), stroke, and the composite outcomes of CV death or HHF and MACE (CV death, nonfatal MI, or nonfatal stroke).

DATA SYNTHESIS

In two trials enriched with people with chronic kidney disease, HHF was more common than both MI and stroke. Among the remaining 14 trials, HHF was less frequent than MI in 13 (93%), with this difference being significant in 8 (57%); however, HHF surpassed stroke in all but 1 study (93%; significant in 7 studies [50%]). Heterogeneity among trials was moderate/high (I2 >50%) and partly explained by HHF/MI correlating with age and previous MI history (P < 0.05). In seven trials that reported events stratified by presence/absence of preexisting CV disease, ratios of HHF/MI and HHF/stroke were similar between groups.

LIMITATIONS

Enrichment of trial populations with those at high risk of CV events limits generalizability.

CONCLUSIONS

Although less frequent than MI, HHF is a common event in type 2 diabetes, both in those with and those without prior CV disease.
Buzlanma Tahmini Yapan Mobil Uygulama Geliştirilmesi
Authors: KABAOĞLU Hatice , UÇAR Emine , DURAN Fecir
Published: September 2020

Soğuk hava ve ağır kış şartları, yollarda buzlanmaya sebep olmakta ve bu nedenle her yıl birçok ölümlü, yaralanmalı ve maddi hasarlı kaza meydana gelmektedir. Bu çalışmada yollardaki buzlanmadan kaynaklı kazaların önlenmesine yönelik bir buzlanma tahmin algoritması ve mobil uygulama geliştirilmiştir. Geliştirilen uygulama ile sürücülerin güzergâhları doğrultusunda buzlanma oluşumu ile ilgili ön bilgi verilmesi amaçlanmaktadır. Çalışmada yol durum sensörü ve hava istasyonlarından alınan sıcaklık, çiğ noktası, hissedilen sıcaklık, rüzgâr şiddeti, rüzgâr yönü, bağıl nem, rüzgâr hızı giriş parametreleri olarak kullanılmıştır. Çıkışta ise buzlanma bilgisi ile ikili sınıflandırma yapılmıştır. Sistemin eğitimi tamamlandıktan sonra meteorolojiden hava durumu tahmin bilgisi alınarak, geliştirilen mobil uygulama üzerinde gelecek 12 saat için buzlanma tahmini yapılmaktadır. Ayrıca geliştirilen sistemin doğruluğunu ölçmek ve karşılaştırma yapabilmek için sınıflandırma alanında en çok kullanılan yöntemlerden çok katmanlı algılayıcı (ÇKA) sinir ağı modeli ile doğrusal ve doğrusal olmayan destek vektör makineleri (DVM) yöntemleri kullanılmıştır. Çalışmada kullanılan algoritmaların sınıflandırma doğruluğuna bakıldığında, toplam doğru sınıflandırılan örnek sayısı temel alındığında ÇKA modelinin %87,26 doğruluk oranı ile en iyi sonucu verdiği, ardından %86,32 ile doğrusal DVM modelinin geldiği önerilen modelimizin ise %75,47 doğruluk oranına sahip olduğu görülmüştür. Ancak geliştirilen tahmin algoritmasında sınıflandırma doğruluğu diğerlerine kıyasla daha az olmasına rağmen eğitimde kullanılan örnek sayısı arttıkça, buzlanma tahmin doğruluğunun da doğru orantılı olarak arttığı gözlemlenmiştir.
Penggunaan Metode Pembelajaran Team Quiz sebagai Upaya Meningkatkan Prestasi Belajar IPA
Authors: Sri Parnayathi I Gusti Agung
Published: September 2020

Kemampuan siswanya untuk kompetensi mata pelajaran IPA cukup rendah. Tujuan penulisan penelitian tindakan kelas ini adalah untuk mengetahui apakah penggunaan Metode Pembelajaran Team Quiz dalam pembelajaran IPA dapat meningkatkan prestasi belajar siswa kelas VIII A. Metode pengumpulan datanya adalah tes prestasi belajar. Metode analisis datanya adalah deskriptif. Hasil yang diperoleh dari penelitian Penggunaan Metode Pembelajaran Team Quiz dalam pembelajaran IPA dapat meningkatkan prestasi belajar siswa kelas VIII A. Ini terbukti dari hasil yang diperoleh pada yang awalnya 65,65 setelah diberikan tindakan pada siklus I meningkat menjadi 69,73 dan pada siklus II meningkat lagi menjadi 78,42. Kesimpulan yang diperoleh dari penelitian ini adalah Penggunaan Metode Pembelajaran Team Quiz.
ANALISIS DISHARMONI TIPOGRAFI DAN WARNA PADA IKLAN LAYANAN MASYARAKAT DI KOTA MEDAN TAHUN 2012
Authors: Gamal Kartono Lulu Karina Hasibuan Dan
Published: September 2020

Abstrak Penelitian ini bertujuan untuk  mengetahui tentang disharmoni yang terjadi pada Iklan Layanan Masyarakat di kota Medan berdasarkan pemilihan tipografi dan warna dengan pertimbangan nilai tingkat kemudahan dalam membaca. Dalam penelitian ini adalah populasi Iklan Layanan Masyarakat yang ada di kota Medan. Adapun sampel dalam peneliian ini  adalah sebanyak 12 iklan layanan masyarakat. sampel yang diambil dengan teknik purposive sample yaitu sampel yang disesuaikan dengan dengan kriteria iklan layanan masyarakat yang dianggap penting dalam kehidupan masyarakat. Metode penelitian yang digunakan pendekatan metode kualitatif deskriptif yaitu dengan menguraikan masing-masing subjek yang akan diteliti dan disesuaikan dengan kerangka teori yang telah ditetapkan. Kata Kunci: Disharmoni, Iklan Layanan Masyarakat, Kota Medan.
PENERAPAN IKON MEDAN SEBAGAI CINDRAMATA PADA BAJU KAOS DENGAN TEKNIK SABLON KUAS DITINJAU DARI PRINSIP-PRINSIP ESTETIKA
Authors: Siregar Siti Rahmadani , Wiratma Sri
Published: September 2020

Penelitian ini bertujuan untuk mengetahui penerapan prinsip-prinsip estetika yang paling menonjol dan yang kurang menonjol pada karya sablon baju kaos yang menampilkan Ikon Medan teknik kuas sebagai cindramata. Prinsip-prinsip estetika tersebut meliputi, kesederhanaan, keserasan, irama, kesatuan dan keseimbangan. Penelitian dilaksanakan dari Juni 2016 sampai Agustus 2016. Metode yang digunakan adalah penelitian deskriptif kualiatatif. Teknik pengumpulan data melalui observasi, wawancara dan dokumentasi. Analisis data melalui proses reduksi data, penyajian data tentang prinsip estetika apa yang menojol dan yang kurang menonjol pada karya 30 sampel yang diteiliti. Bahwa, secara umum dapat di kategorikan baik dengan jumlah rata-rata (r) 80,87 (baik). Penilaian yang lebih tinggi terdapat pada unsur Keselarasan dengan nilai 82,66 kategori baik dengan skala 3 dan yang lebih rendah adalah unsur Keseimbangan dengan nilai 79,94 kategori cukup dengan skala 2. Sementara unsure yang lain seperti Kesatuan 81,42 kategori baik dengan skala 3, Irama dengan nilai 80,89 dan kesederhanaan dengan nilai 81,67 kategori baik dengan skala 3. Kata Kunci : Ikon Medan, Cindramata, Prinsip-Prinsip Estetika
ANALISIS KAIN SONGKET MELAYU LANGKAT DITINJAU DARI BENTUK ORNAMEN, WARNA, MAKNA SIMBOL DAN NILAI ESTETIKA
Authors: Rizali Muhammad , Azmi Azmi
Published: September 2020

Penelitian ini bertujuan untuk mengetahui bentuk ornamen, warna, makna simbol dan nilai estetika yang terkandung kain songket Melayu Langkat di Desa Pekubuan Kabupaten Langkat. Waktu penelitian selama 2 bulan yaitu pada awal Juni sampai dengan Juli 2016. Lokasi penelitian adalah daerah Langkat, Sumatera Utara. Populasi pada penelitian ini berjumlah 10 kain songket Melayu Langkat. Penelitian ini menggunakan metode deskriptif kualitatif dengan menguraikan masing-masing subjek yang akan diteliti, dengan menggunakan dua data yakni data primer diperoleh  dari survei lapangandan dokumentasi yaitu mengamati langsung objek yang diteliti. Sedangkan data sekunder diperoleh melalui wawancara. Hasil mengkaji 10 kain songket Melayu Langkat menunjukkan bahwa terdapat 14 motif yang diterapkan pada kain songket Melayu Langkat.Kata Kunci : Bentuk Ornamen, Warna, Makna Simbol Dan Nilai Estetika.