bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Si Addition in NiCrAl Coating on Corrosion in Molten Nitrate Salt
Authors: Kettrakul Patchaporn , Siripongsakul Thamrongsin , Kanjanaprayut Noparat , Wiman Panya , Promdirek Piyorose
Published: August 2023

The materials used in concentrating solar power (CSP) systems are becoming of interest because of high energy efficiency of energy storage. It can apply molten salts as heat storage media and heat transfer fluid in a CSP system. In molten salts, steel alloys such as vessels, pipe-lines, and heat exchangers are very vulnerable to hot corrosion. To protect steel alloys, coating is an excellent strategy to lengthen the service lifetime and reduce the maintenance cost. NiCrAl coatings are suitable candidates for a high temperature environment. Thus, this research aims to investigate the corrosion behaviour in molten salt of NiCrAl coatings on AISI304 stainless steel with Si addition in the coating. NiCrAl coatings with and without Si addition were deposited using the high-velocity oxygen fuel (HVOF) technique. The corrosion test was performed using the immersion test in the modified molten salt (solar salt + 0.5%NaCl) at 400, 500 and 600°C. The gravimetric method was used to evaluate weight change for the immersion test. At 400°C, more evident weight gain due to molten salt infiltration was observed rather than oxidation reaction. At 600°C, oxidation became more dominant and oxidation products NiO and sodium-aluminium-silicate were detected. Si addition resulted in supporting the formation of the protective oxide, sodium-aluminium-silicate which was acting as a blockade against molten salt infiltration. Furthermore pore spaces were replaced by the protective oxide in the coating surface. The reactions related to oxide formation and hot corrosion were further discussed.
Negative expression of CD117 predicted inferior OS and PFS in acute promyelocytic leukemia
Authors: Zeng Hui , He Jie , Dong Hai-Bo , Zhou Min , Zhang Qian , Chen Lan-Xin , Yuan Cui-Ying , Jiang Ru-Ru , Liu Jin-Wen , Ou-Yang Jian , Ben Yu , Chen Bing
Published: August 2023

Up to date, there are few reports on the clinical significance of CD117 antigen in acute promyelocytic leukemia (APL), especially CD117−APL. In this study, we retrospectively investigated the clinicopathological characteristics, outcome and prognostic effect of CD117 antigen negativity in 169 APL patients treated with ATRA-ATO regimen. The median follow-up period was 63.0 months. CD117− was found in 13 APL patients (7.7%). No significant differences were found in baseline characteristics between CD117+ and CD117− subgroups. Compared with CD117+ APL, the incidence of early death (ED) in CD117− APL was significantly higher (P = 0.023). By multivariate analysis, CD117 negativity was an independent adverse prognostic factor for overall survival (OS) and progression-free survival (PFS) (P = 0.040 and P = 0.030, respectively). In conclusion, negative CD117 expression is associated with greater risk of ED and has the statistical power to predict inferior OS and PFS, this marker may be considered to build prognostic scores for risk-adapted therapeutic strategies in APL.
Long-term effects of sustained regular medication in hypertensive patients: a cohort study in China
Authors: MA Min , Wang Huadan , Pang Linhong , Guo Zihong , Sun Manli , Zhao Yajing , Shi Yi , Wu Xia , Song Junjie , Zhu Qiuyan , Duo Lin , Wang Zhongjie , Xia Yu , Tang Mingjing , He Liping
Published: August 2023

Background The relationship between different grades of compliance to antihypertensive medication and blood pressure(BP) control rate remains unclear. The study underscores the relationship that long-term compliance with regular antihypertensive medication to improve rates of BP control.Methods Using 5-year follow-up data, hypertensive patients were categorized into "poor", "intermittent", and " sustained" groups according to tertiles of antihypertensive medication compliance, and the BP control rates of the three groups were compared.Then, the robust variance Poisson regression model estimated the association between three groups and the number of referrals. Kaplan-Meier calculated the cumulative risk of onset and survival probability of cardiovascular events from three medication compliance groups.Results A total of 1254 patients were enrolled and annual follow-up studies of 992, 1218, 1121, 1066 and 999 hypertensive patients were conducted from 2018 to 2022. From baseline to last follow-up, systolic BP declined from 154.69 ± 20.90 mmHg to 137.48 ± 12.44 mmHg and diastolic BP from 84.08 ± 12.80 mmHg to 79.50 ± 7.88 mmHg (p < 0.01). All three groups showed a significant improvement in BP control rates after management, especially the persistence group which reached 70% in 2022(p < 0.01). The number of referrals from the poor group was 11.5% higher than the sustained group (IRR = 1.115,95% CI:1.043 to1.193). The survival probability in the sustained group was the highest and kept at 0.950 at the end of 5 years.Conclusions Long-term high-grade compliance with antihypertensive medications significantly improves BP control rates and reduces the risk of cardiovascular disease (CVD) events and death.
Assessing Social Media Usage in Public Participation for Rapid Bus Transit Project Using Machine Learning
Authors: Yasin Eman
Published: August 2023

This paper aims to perform assessment of socialMedia usage, particularly Twitter, in public participation (PP) forInfrastructure projects in developing countries. The case of BusRapid Transit (BRT) of Jordan has been chosen as a case study.A comprehensive literature review was accomplished, followedby scraping the Arabic tweets relevant to the project. The tweetswere divided into three main periods, according to logical rea-soning as described in the paper. Tweets were then prepossessedincluding cleaning, tokenization, vectorization using AraBert toensure the highest contextualization for machine learning. Thefollowing analyses were performed: tweeting intensity, sentimentanalysis, tweets fluency and topic modeling. Findings of thisstudy reveals many difficulties associated with the public par-ticipation in the BRT project. The results indicated that lackof trust, appropriate communication and transparency createdlarge gap between the public and the project directors. Thisgap led to inappropriate public participation in the project, andconsequently high resistance as observed by the author. Findingsof the paper provide valuable insights for project managersand decision-makers. Understanding the public participationdimensions, the consequences of social media usage may improvepublic engagement and support the success of infrastructureprojects in developing countries like Jordan.
Cold-inducible RNA-binding protein induces inflammatory responses via NF-κB signaling pathway in normal human bronchial epithelial cells infected with streptococcus pneumoniae
Authors: Zhang Rong , Fang Kun , Mu Chunyan , Li Fujun , Zhang Liang
Published: August 2023

Background
Community-acquired pneumonia is a significant cause of morbidity and mortality worldwide, with substantial clinical implications that warrant further investigation and intervention. The invasion of Streptococcus pneumoniae (S. pneumoniae, S.p) can result in serious conditions such as meningitis, sepsis or pneumonia. Extracellular Cold-inducible RNA-binding protein (eCIRP) acts as a damage-associated molecular pattern that triggers inflammatory responses and plays an important role in both acute and chronic inflammatory diseases. It remains unclear whether CIRP is involved in the process of S. pneumoniae infection in normal human bronchial epithelial cells (BEAS-2B).
Methods
Cell counting kit (CCK)-8 assay was used to detect the activity of BEAS-2B cells after Streptococcus pneumoniae infection. The distribution of CIRP in BEAS-2B cells was detected by immunofluorescence. Quantitative real-time PCR (PCR) and Western Blot (WB) were used to detect the expression of CIRP, nuclear factor kappa-B (NF-κB) p65, toll like receptor-4 (TLR4), interleukin-6 (IL-6), etc. The expressions of CIRP, IL-1β, IL-6, tumor necrosis factor-α (TNF-α) and monocyte chemoattractant protein-1 (MCP-1) were assessed by enzyme linked immunosorbent assay (ELISA).
Results
We discovered that CIRP affected the activity of BEAS-2B cells that were induced by S. pneumoniae infection. After S. pneumoniae infection, CIRP transferred from the nucleus to the cytoplasm, and pro-inflammatory cytokines (IL-1, IL-6, TNF-α and MCP-1) were then produced. We further found that a significant increase in the expression of NF-κB p65 protein following S. pneumoniae infection of BEAS-2B cells, which was significantly reduced upon si-CIRP interference. Treatment with TLR4 neutralizing antibodies and an NF-κB inhibitor resulted in a significant decrease in the expressions of IL-1β, IL-6, TNF-α and MCP-1 in BEAS-2B cells.
Conclusions
Infection with S. pneumoniae induces an upregulation of CIRP expression and translocation from the nucleus to the cytoplasm in BEAS-2B cells, which subsequently leads to the release of proinflammatory factors via activation of NF-κB signaling pathway. The identification of CIRP as a key mediator in S. pneumoniae-induced inflammation provides potential targets for therapeutic intervention against community-acquired pneumonia.
Antimicrobial resistance and the prevalence of the Panton-Valentine Leukocidin gene among clinical isolates of Staphylococcus aureus in Lithuania
Authors: Kirkliauskienė Agnė , Kriščiūnas Jonas , Miciulevičienė Jolanta , Radzišauskienė Daiva , Kačergius Tomas , Bratchikov Maksim , Kaplerienė Lina
Published: August 2023

Background
Staphylococcus aureus is one of the most frequently identified pathogens causing nosocomial infections worldwide and, in many cases, exhibits resistance to multiple antimicrobials. However, there is a lack of data about the prevalence of S. aureus resistance to antimicrobials in major hospitals in Vilnius city, Lithuania. Therefore, the aim of this study was to determine the resistance to antimicrobials of Staphylococcus aureus strains isolated from clinical specimens in Lithuanian hospitals and to identify the genes conferring resistance and virulence.
Methods
This study was carried out from June 2019 to September 2021. S. aureus strains were isolated from clinical specimens. Antibiotic susceptibility testing was performed by the disc diffusion method according to EUCAST guidelines. All our collected isolates were analysed for detection of the ermA, ermC, mecA, mecC, tetK, tetM and lukF-PV genes by multiplex real-time PCR. The 16S rRNA coding sequence was applied as an internal PCR control.
Results
A total of 745 S. aureus strains isolated from clinical specimens were analysed. A total of 69.0% of strains were isolated from the skin and soft tissues, 14.5% from blood, 11.7% from the lower respiratory tract, 2.7% from urine and 2.1% from other specimens. Antimicrobial susceptibility testing revealed that all 745 isolates were susceptible to rifampin and vancomycin. Of the 745 strains, 94.8% were susceptible to tetracycline, 94.5% to clindamycin and 88.3% to erythromycin. The lowest susceptibility rate was found to penicillin (25.8%). Six percent of the tested strains were methicillin-resistant S. aureus (MRSA). The majority of methicillin-resistant strains were isolated from skin and soft tissues (73.3%), with a smaller portion isolated from blood (17.8%) and the respiratory tract (8.9%). The ermC gene was detected in 41.1% of erythromycin-resistant S. aureus strains, whereas ermA was detected in 32.2% of erythromycin-resistant S. aureus strains. A total of 69.2% of tetracycline-resistant S. aureus strains had the tetK gene, and 28.2% had the tetM gene. A total of 7.3% of S. aureus isolates harboured the lukF-PV gene. The frequency of pvl gene detection was significantly higher in the MRSA isolates than in the methicillin-susceptible S. aureus (MSSA) isolates (p < 0.0001).
Conclusions
All tested strains were susceptible to rifampicin and vancomycin. A total of 6% of the strains were MRSA. The lowest susceptibility rate was found to penicillin. The tetK gene was predominant among S. aureus strains resistant to tetracycline, and the ermC gene was predominant among erythromycin-resistant strains. Seven percent of S. aureus isolates harboured the lukF-PV gene, which was more prevalent in methicillin-resistant strains.
The Association Between Different Digital Use and Young Adults’ Well-being
Authors: Chen Yijun , Zhang Xiaochu , Akaishi Rei
Published: August 2023

Digital technology, particularly smartphones, has become an integral part of modern life, raising concerns about its impact on well-being, especially among young people. Previous studies have yielded inconsistent results, possibly due to a lack of differentiation between different types of digital use and an overemphasis on the connection between smartphone use and well-being while neglecting confounding variables such as face-to-face communication time. In this pre-registered study, we employed the experience sampling method (ESM) to track the daily activities of 418 individuals over 21 days and analyzed the data using multilevel models and psychometric network models. Our study specifically examined the effects of different communication targets (one-to-one vs. one-to-many) and communication modes (online vs. offline). The findings revealed that digital use has only a small direct effect on well-being, with negative impact of one-to-many online communication (e.g., viewing Twitter or Instagram). Increased digital use was found to reduce offline communication time, indirectly influencing well-being to a large degree. Overall, this study has the potential to reconcile the inconsistent findings regarding the effects of digital technology on well-being with indirect effects through reduction of offline communication time. The negative impact of one-to-many online communication, which constitutes a significant portion of digital use time, warrants further attention.
Analisis Kesalahan Ejaan dalam Teks Deskripsi Siswa Kelas VII SMP Negeri 14 Surakarta
Authors: Fadhilah Elsya Primaratri , Syariani Syariani , Ulya Chafit
Published: August 2023

Language errors are the symptoms that cannot be separated from language learning. Language errors are often found in the description text of students' works. This research aims to describe the errors in writing Indonesian language spelling in a collection of descriptive text works by grade VII students of SMP Negeri 14 Surakarta. This research is a descriptive research which uses a qualitative approach. The data sources for this research are 12 descriptive texts by grade VII students of SMP Negeri 14 Surakarta. The data in this research are spelling errors in 12 student description texts. Data collection uses documentation techniques. This research is carried out with the steps of (1) collecting sample data sources; (2) analyzing data and finding spelling errors in data sources; (3) classifying errors; (4) describing spelling errors in the data; (5) evaluating errors and finding corrections. The results show that there are 108 spelling errors in the descriptive text of the students' works at SMP Negeri 14 Surakarta. These spelling errors include errors in writing capital letters, writing prepositions, writing abbreviations, writing punctuation, writing repeated words, and writing affixes.
Makna Adverbial dalam Buku Panduan Memasak sebagai Bahan Ajar Materi Teks Prosedur Kurikulum Merdeka
Authors: Hartanto Fajrin Ilham , Setiyanto Gumawang
Published: August 2023

This study aims to describe the meaning of adverbs in cooking guide books. Descriptive qualitative method is the method used in this study. The data source for this research is a cooking guide book entitled “Solo Traditional Culinary which is Rare”. In addition, the data of this study are procedural sentences containing adverbial meanings. Data analysis uses matching and distribution methods. The results of this study state that the cooking guide book entitled “Solo Traditional Culinary which is Rare” contains several adverbial meanings along with the amount of data found: the meaning of 'time': until (33), to (2), when (1), after (3), during (4), approximately (1), approximately (1); meaning of 'place': from (1), in (10), to (8), in (5), on (9); meaning of 'tool': with (17); the meaning of 'way': with (4); meaning of 'conditions': if (5); the meaning of 'purpose': in order to (3); the meaning of 'inclusion': while (4), along with (5); and the meaning of 'as a result': so (1). By finding some of these adverbial meanings, it can be used as teaching material for the procedural text of Kurikulum Merdeka.
Analisis Kesalahan Berbahasa Tataran Fonologi dan Morfologi pada Teks Sinopsis Cerita Karya Siswa Kelas V SD Negeri Menuran 03 Sukoharjo
Authors: Setyaningsih Arinda Oktariski
Published: August 2023

Language occupies a very crucial role for humans in this life, especially in terms of communication with other humans. One of the language skills used to communicate indirectly is writing skill. In the world of writing, writing mistakes have become a natural thing. Therefore, this study aims to improve and describe various errors in the Indonesian language at the phonological and morphological levels in the story synopsis text by students of class V SD Negeri Menuran 03. The method used in this study is a qualitative descriptive method. The data source in this study came from written data in the form of story synopsis text results, while the data collection technique used was reading and note-taking techniques. The results of this study indicated that there were 45 language errors at the phonological and morphological levels. At the phonological level (adding phonemes, changing phonemes, and removing phonemes) there were 30 errors or 66.7%, while at the morphological level (affixation and reduplication) there were 15 errors or 33.3%.
Analysis of the Strategic Approach to Industrial Development in Russia
Authors: Sasaev Nikita
Published: August 2023

The article analyzes the strategic approach to industrial development in Russia. The author studied the regulatory environment, i.e., strategies, programs, and projects, that affects economic sectors and sets the vector of industrial development. A detailed analysis of these strategies, programs, and projects revealed a number of significant shortcomings that reduce the effectiveness of the public administration system for long-term industrial and socio-economic development. The author described the theoretical foundations of economic and industrial development, best practices in building effective industrial growth drivers, and existing methodological flaws in the strategic approach to industrial strategies in Russia. The research revealed the need to change the methodological approach to strategizing in Russia. As an effective solution, the author proposed the methodology of industrial strategizing based on the general theory of strategy and methodology of strategizing developed by the National School of Strategizing and Professor Vladimir L. Kvint, Dr.Sc. (Econ.), Foreign Member of the Russian Academy of Sciences.
Multimodal climate change prediction in a monsoon climate
Authors: Mohan Sankaralingam , Sinha Akash
Published: August 2023

The uncertainty in the climate projection arising from various climate models is very common, and averaging such results poses a risk of underestimation or sometimes overestimation of impact in magnitude and frequency. Further, the performance of various climate models in monsoon degrades drastically due to the skewed nature. Under these circumstances, the performance of the climate model in the monsoon and non-monsoon periods is critical for accurate assessment. A multimodal approach has been used in the present work to quantify the uncertainty involved in the climate model using reliability ensemble averaging (REA). Based on AR6 of IPCC, the ensemble of 26 global climate models (GCMs) was used to evaluate the model performance and possible change in seasonal precipitation in four cities with distinct climate conditions, namely, Coimbatore, Rajkot, Udaipur, and Siliguri. The results show that non-monsoon and monsoon rainfall are expected to increase in all the regions. Most of the models perform poorly in simulating monsoon climate, especially in the monsoon period and are highly inconsistent spatially. The study also finds that the model performance is largely linked to the ratio of natural variability and mean.
Assessment of carbon neutrality in waste water treatment systems through deep learning algorithm
Authors: Sundar L. Syam , Almujibah Hamad , Alshahri Abdullah H. , Ancha Venkata Ramayya
Published: August 2023

Around the world, it is growing harder to provide clean and safe drinking water. In wastewater treatment, sensors are employed, and the Internet of Things (IoT) is used to transmit data. Chemical oxygen demand (COD), biochemical demand (BOD), total nitrogen (T-N), total suspended solids (TSS), and phosphorous (T-P) components all contribute to eutrophication, which must be avoided. The wastewater sector has lately made efforts to become carbon neutral; however, the environmental impact and the road to carbon neutrality have received very little attention. The challenges are caused by poor prediction. This research proposes deep learning modified neural networks (DLMNN) with Binary Spotted Hyena Optimizer (BSHO) for modeling and calculations to address this challenge. All efforts for resource recovery, water reuse, and energy recovery partially attain this objective. In contrast to previous modeling techniques, the DLMNN-training BSHOs and validation demonstrated outstanding accuracy shown by the model's high coefficient (R2) for both training and testing. Also covered are recent developments and problems with nanomaterials made from sustainable carbon and graphene quantum dots, as well as their uses in the treatment and purification of wastewater. The proposed model DLMNN-BSHO achieved 95.936% precision, 95.326% recall, 93.747% F-score, and 99.637% accuracy.
A Review on the Anticancer Activity of Carbazole-based Tricyclic
Compounds
Authors: Zhang Hua , Zhang Wen , Zhu Mengyu , Awadasseid Annoor
Published: August 2023

:

Cancers are a huge threat to human life and health. Every year, many people
suffer and die from various cancers, and numerous resources have been used to combat
cancer. Due to several disadvantages of anticancer agents, such as drug-induced side effects,
drug resistance, etc., there are still wide gaps in their ability to conquer cancer.
Therefore, there is an urgent need to discover and develop many novel chemotypes to
suppress cancer. In this review, we mainly focus on the anticancer potency of two representative
sorts of carbazole-based compounds: carboline derivatives and diazacarbazole
derivatives. Diazacarbazole derivatives, which have not been fully explored yet, might
bring us a new vision and a valuable opportunity for overcoming the enormous hurdle we
are now facing in the cancer campaign. We also provide several synthetic approaches for
constructing the critical skeletons of the carbazole-based tricyclic compounds.
Atezolizumab Lung Toxicity: Importance of Combination Treatment On
The Edge of Life, A Case Report
Authors: Koc Aysu Sinem , Can Orcun , Kobak Senol
Published: August 2023

Background:

Lung cancer is one of the most common and mortal cancers worldwide. According to pathological and clinical groups, treatments vary, and a tailored approach is considered. Adjuvant therapies, such as chemotherapy, radiation, and immune checkpoint inhibitors (ICI), are recommended by recent guidelines for patients with locally advanced cancer.

Objective:

This study aimed to report the case of a patient with stage 2B squamous cell lung carcinoma who was managed for pulmonary toxicity after receiving adjuvant chemotherapy and atezolizumab treatment.

Case report:

A 66-year-old male patient received chemotherapy and immunotherapy after surgery for squamous cell lung cancer. A diagnosis of atezolizumab-associated pneumonitis was made using laboratory tests and imaging due to the patient's worsening dyspnea after treatment. Due to the patient's rapid progression, pulse steroid and MMF therapy were administered concurrently. When Klebsiella pneumoniae growth was detected in the sputum culture during the follow-up, IVIg was used to supplement the medication. The patient showed significant clinical and radiological improvement.

Conclusion:

In this study, we present an atezolizumab-induced pneumonitis case of a squamous cell lung cancer patient. It may be life-saving not to avoid aggressive treatment approaches by combining the steps of guideline recommendations in patients with rapidly progressive pneumonitis.
The Effect of Fingolimod on Renal Ischemia/Reperfusion Injury in a Rat Model
Authors: Bagheri Yasin , Ahmadian Elham , Hejazian Seyyedeh Mina , Raeesi Maryam , Zununi Vahed Sepideh , Ardalan Mohammadreza
Published: August 2023

Background:

Ischemia/reperfusion injury (IRI) is a leading cause of acute kidney injury (AKI) that induces inflammation and oxidative stress. The main goal of the current study was to assess the impact of fingolimod on kidney IRI in rats.

Methods:

For this purpose, 18 male Wistar rats (220–250g) were divided into three groups including (i) Sham, (ii) I/R, and (iii) fingolimod+I/R. The last group was pretreated with a single dose of fingolimod (1mg/kg) (intraperitoneal injection) before induction of the I/R injury. Kidney function, oxidative stress marker (malondialdehyde), and antioxidant markers (catalase, superoxide dismutase, glutathione, glutathione peroxidase, and total antioxidant capacity) were determined in the kidney tissue of the rats. Moreover, kidney samples were taken for histological analysis.

Results:

Fingolimod pre-treatment could significantly improve the glutathione peroxidase (p<0.01) and glutathione (p<0.001) activities along with the total antioxidant capacity levels (p<0.001) when compared to the I/R group. Moreover, significant recovery of kidney function and histology was seen in the fingolimod+ I/R group compared to the I/R group (p<0.01).

Conclusion:

Fingolimod pretreatment could improve renal function, antioxidant capacity, and histological alterations after I/R injury. Hence, it might protect the kidney against IRI-related kidney damage including AKI and transplantation.
The effect of a WeChat-based gamification intervention on the self-management ability of patients with coronary heart disease: pilot randomized controlled trial (Preprint)
Authors: Chen Kun , Yu Chunguang , Tian Runxi , He Shu , Zhang Shiyu
Published: August 2023

BACKGROUND

A healthy lifestyle is an essential component of the successful treatment of coronary heart disease. Despite manifest evidence for the many health benefits of lifestyle changes, it is difficult for patients to achieve sustained changes in health behaviors. There is evidence that mHealth-based gamified interventions can promote health behavior change in patients, but studies in China are scarce.

OBJECTIVE

The study aimed to evaluate the effect of an 8-week WeChat-based gamified intervention on self-management ability compared with a waiting control group in Chinese CHD patients.

METHODS

A single-blind randomized controlled trial of CHD patients in Beijing, from November 2022 to February 2023. The primary outcome was coronary self-management behavior, measured using the Coronary Self-Management Behavior Scale. After recruitment at the Department of Cardiology, Dongzhimen Hospital, Beijing University of Chinese Medicine, 86 patients were randomly assigned to the intervention and control groups. The intervention group received an 8-week WeChat-based gamification intervention, and the control group received the usual care. A total of 2 assessments were conducted, 1 at the beginning of the intervention (T1, N=86) and 1 at the end of the 8-week intervention (T2, N=74).

RESULTS

Eligible patients (N=86) were randomized to the intervention (n=43) or the control (n=43) group. 74 patients eventually completed the clinical pilot study, including 38 in the trial and 36 in the control groups. Participants were predominantly male (47/74, 63.5%), and retiree (28/74, 37.8%), with a mean age of 63.2 ± 9.7 years. A significant treatment effect in favor of the intervention was observed for the primary outcome at 8 weeks (P=.03). The intervention group reported significantly greater knowledge level and self-efficacy (P＜.001 and P=.03, respectively).

CONCLUSIONS

Patients’ self-management ability, disease knowledge, and self-efficacy can be improved by a WeChat-based gamified intervention that focuses on self-management. Such an intervention provides a viable means of self-management for patients with coronary heart disease and a reference for self-management of other chronic diseases.

CLINICALTRIAL

the name of registry: The effect of a WeChat-based gamification intervention on the self-management ability of patients with coronary heart disease: study protocol of a randomized controlled trial
registration number:ChiCTR2200067108
URL of the registry:https://www.chictr.org.cn/showproj.html?proj=178392
TINJAUAN YURIDIS ADANYA KEKERASAN DALAM RUMAH TANGGA SEBAGAI ALASAN UNTUK MELAKUKAN PERCERAIAN
Authors: Mayasari Dian Ety
Published: August 2023

In marriage between husband and wife disputes often occur not infrequently accompanied by violence perpetrated by one party and led to divorce. One of the reasons that lead to divorce in Article 19 of Government Regulation No. 9 of 1975 was particularly severe cruelty or mistreatment to harm others. When one of the victims of domestic violence and can show strong evidence in the trial as well as husband and wife can not live together in a household, then the divorce petition can be granted court pursuant to Article 39 paragraph (1) of Law No. 1 of 1974. Dalam perkawinan antara suami dan istri sering terjadi perselisihan yang tidak jarang disertai dengan kekerasan yang dilakukan oleh salah satu pihak dan mengakibatkan terjadinya perceraian. Salah satu alasan yang menyebabkan perceraian dalam Pasal 19 Peraturan Pemerintah Nomor 9 Tahun 1975 adalah salah satu pihak melakukan kekejaman atau penganiayaan berat yang membahayakan orang lain. Ketika salah satu korban kekerasan dalam rumah tangga dan dapat menunjukkan bukti yang kuat dalam persidangan serta suami dan istri tidak bisa hidup bersama dalam sebuah rumah tangga, maka permohonan perceraian dapat diberikan sidang pengadilan berdasarkan ketentuan Pasal 39 ayat (1) UU No. 1 Tahun 1974.
AKIBAT HUKUM PEMBUBARAN BP MIGAS
Authors: Mujiburohman Dian Aries
Published: August 2023

This paper discusses the Constitutional Court Decision Number 36/PUU-X/2012 concerning judicial review of Law Number 22 Year 2001 on Oil and Gas, which contains the dissolution judgment Oil and Gas Executive Agency (BP Migas). This study focuses on meaning of the State Control over Oil and Natural as resources which is considered to be degraded by the presence of BP Migas and the legal consequences after the dissolution of BP Migas, the impact of the dissolution to institution of the above mentioned, BP Migas, the contract of cooperation and the status of their employees. Tulisan ini membahas tentang Putusan Mahkamah Konstitusi Nomor 36/PUU-X/2012 perihal Pengujian Undang-Undang Nomor 22 Tahun 2001 tentang Minyak dan Gas Bumi, putusan yang berisi pembubaran Badan Pelaksana Minyak dan Gas Bumi (BP Migas), kajian ini menitikberatkan pada makna Penguasaan Negara atas Sumber Daya Alam Migas yang dianggap telah terdegradasi oleh keberadaan BP Migas dan apa akibat hukum pasca pembubaran BP Migas terhadap kelembagaan, kontrak kerja sama, status pengawas BP Migas.
THE SIGNIFICANCE OF THE COMPLEMENTARITY PRINCIPLE WITHIN THE ROME STATUTE IN INTERNATIONAL CRIMINAL LAW
Authors: Triyana Heribertus Jaka
Published: August 2023

In practice, the application of the complementarity principle in the Rome Statute remains unclear, particularly with respect to the prioritization of national penal law jurisdiction. This paper willdiscuss the relevance of the complementarity principle to the development of a national criminal justice system and to the investigation and prosecution of the most serious crimes provided for in the Statute. It was concluded that the complementarity principle should be used to unravel the twisted development of the national criminal justice system in accordance with the provisions of international law. We need to establish our national criminal justice system as the main and foremost forum (hence, willing and able) in the process of investigating and prosecuting the most serious crimes on earth. Dalam praktik, aplikasi Asas Pelengkap (the complementarity principle) dalam Statuta Roma masihbelum jelas, khususnya terkait dengan pengutamaan (prioritization) yurisdiksi hukum pidana nasional. Oleh karena itu, tulisan ini akan membahas relevansi asas tersebut terhadap pembangunan sistem hukum pidana nasional dan terhadap penyelidikan dan penuntutan kejahatan paling serius yang diatur dalam Statuta. Disimpulkan bahwa Asas Pelengkap harus Mahkamah digunakan sebagai pengurai benang kusutpembangunan sistem hukum pidana nasional Indonesia sesuai dengan ketentuan hukum internasional supaya menjadi forum utama (mau dan mampu) dalam proses penyelidikan dan penuntutan kejahatan paling serius di muka bumi.
EFFECTIVENESS OF THE WORLD TRADE ORGANIZATION’S DISPUTE SETTLEMENT MECHANISM
Authors: Alfaqiih Abdurrahman
Published: August 2023

Many WTO (World Trade Organization) member States have made use of the WTO dispute settlement mechanism. Nevertheless, the debate over the effectiveness of this mechanism is still happening and is animportant issue to be discussed. This article aims to explain the effectiveness of the WTO dispute settlement mechanism. Its time frame, participation (particularly developing countries) and its achievements areu sed to measure such effectiveness. This article concludes that the WTO dispute settlement mechanism effectively resolves the disputes among the members. Tidak sedikit negara-negara anggota WTO (World Trade Organization) memanfaatkan mekanisme penyelesaian sengketa dagang internasional di WTO. Namun demikian, perdebatan tentang keefektifan mekanisme ini masih terus terjadi dan menjadi isu yang penting untuk dikaji. Tulisan ini bertujuan untukmenjelaskan argumentasi efektifitas mekanisme penyelesaian sengketa dagang internasional di WTO. Pendekatan waktu, partisipasi (khususnya negara berkembang) dan pencapaian menjadi tolak ukur pengukuran efektifitas mekanisme tersebut. Tulisan ini menyimpulkan bahwa mekanisme penyelesaian sengketa dagang internasional di WTO berjalan secara efektif.
CLASS ACTION AGAINST THE NON-IMMEDIACY OF RATIFICATION OF THE 1990 MIGRANT WORKERS CONVENTION
Authors: Dewanto Wisnu Aryo
Published: August 2023

Ratification of treaties in Indonesia can be regarded as mere political acts, as ratification itself  does not yet rule for its enforcement in Indonesia’s jurisdiction. As stipulated in Article 11 of the 1945Indonesian Constitution, these ratifications are still subject to consent from the Indonesian House of Representatives (DPR) as they are the appointed institution in Indonesia with treaty-making powers. The act of ratification by the Indonesian Government is regarded as a ratification only in the international sense, where such action would only make the treaty enter into force internationally, but not internally within Indonesia. This paper seeks to analyze the legal implications which signatureand ratification of international treaties may hold in the Indonesian government. Such is done by studying the class action lawsuit for Indonesia being signatories the Convention on the Protection of the Rights of All Migrant Workers and Member of Their Families and its failure continue to further ratify the Convention. Ratifikasi perjanjian internasional merupakan tindakan politik yang memerlukan persetujuan dari  Dewan Perwakilan Rakyat (DPR) sebagai lembaga dengan treaty-making power sebagaimana yangdiatur oleh Pasal 11 UUD 1945. Tindakan ratifikasi oleh Pemerintah Indonesia hanya bermakna sebagairatification hanya dalam the international sense, yakni membuat perjanjian tersebut berlaku di levelinternasional, bukan berlaku di wilayah hukum Republik Indonesia. Artikel ini menganalisis proses andimplikasi hukum diratifikasinya dan ditandatanganinya suatu perjanjian internasional oleh PemerintahIndonesia dengan menelaah gugatan class action yang dilakukan terhadap Pemerintah Indonesia mengenaibelum diratifikasinya Konvensi Buruh Migran.
REGULATION ON FOREIGN INVESTMENT RESTRICTIONS AND NOMINEE PRACTICES IN INDONESIA
Authors: Kairupan David
Published: August 2023

Certain provisions of Presidential Regulation No. 36 of 2010 concerning Negative Investment List are not clearly stipulated. In relation to the restrictions of foreign investment in certain business sectors asspecified in the Negative Investment List Article 33 para. (1) and (2) of the 2007 Investment Law expressly prohibits investors from entering into any nominee shareholding documentation. Notwithstanding, manynominee shareholding practices are still employed in Indonesia, aiming to circumvent such restrictions.This paper addresses certain issues on Presidential Regulation No. 36 of 2010 and nominee shareholding practices in Indonesia. Beberapa ketentuan dalam peraturan Presiden No. 36 Tahun 2010 yang mengandung ketentuan Daftar Negatif Investasi tidak dirumuskan secara jelas. Sehubungan dengan pembatasan kepemilikan modal asing di beberapa sektor usaha, Pasal 33 ayat (1) dan (2) Undang-Undang Penanaman Modal No. 25 Tahun 2007 secara tegas melarang penanam modal membuat dokumen-dokumen yang terkait dengankepemilikan saham secara nominee. Namun demikian, praktik kepemilikan saham secara nominee masih sering dilakukan di Indonesia untuk menghindari pembatasan tersebut. Tulisan ini akan membahasbeberapa permasalahan yang berhubungan dengan Peraturan Presiden No. 36 Tahun 2010 dan praktek kepemilikan saham secara nominee di Indonesia.
FAKTOR HISTORIS, SOSIOLOGIS, POLITIS, DAN YURIDIS DALAM PENYUSUNAN RUU HAP
Authors: Gunarto Marcus Priyo
Published: August 2023

After thirty years of its application, the Criminal Procedural Code shows a number of weaknesses in its implementation. The idea to overcome the weaknesses of the criminal procedural law, among others, is by replacing the Law No. 8/1981 on the Criminal Procedural Code. To formulate a draft Criminal Code, there are some aspects that needs to be considered namely historical, sociological, political and legal issues. Because the Criminal Procedure Code, which acts as a guide in court examinations, involves different sectors of the law enforcements, the draft on the Criminal Procedural Code should be a multisector act. Setelah berlaku selama lebih tiga puluh (30) tahun sebagai hukum positif, Kitab Undang-undang Hukum Acara Pidana menunjukkan sejumlah kelemahan dalam pelaksanaannya. Gagasan untuk mengatasi kelemahan dari hukum acara pidana, antara lain dilakukan dengan mengganti Undang-Undang No. 8 Tahun 1981 tentang Kitab Hukum Acara Pidana. Untuk merumuskan Rancangan Hukum Acara Pidana, ada beberapa aspek historis, sosiologis, politik dan yuridis yang harus dipertimbangkan. Oleh karena Hukum Acara Pidana sebagai pedoman untuk memeriksa pengadilan umum akan melibatkan beberapa unsur penegak hukum, maka Rancangan Undang-Undang Hukum Acara Pidana harus ditempatkan sebagai undang-undang multisektor.
INTELLECTUAL PROPERTY LAW IN INDONESIA AFTER 2001
Authors: Sinaga Valerie Selvie
Published: August 2023

This paper reviews the major changes of intellectual property condition in Indonesia after 2001. In that year, Indonesia, which has become a member of the Agreement on Trade Related Aspects of Intellectual Property Rights (TRIPS) since 1994, was ready to meet its commitment under TRIPS. To do so, Indonesiahas made changes in the areas of legislation, administration, court proceedings, and law enforcement. The paper also discusses problematic issues surrounded the implementation of such changes in Indonesia. Tulisan ini melihat kembali perubahan-perubahan besar dalam bidang hak kekayaan intelektual di Indonesia setelah tahun 2001. Pada tahun tersebut, Indonesia, yang telah menjadi anggota Agreement on Trade Related Aspects of Intellectual Property Rights (TRIPS) sejak 1994, siap untuk memenuhi komitmennya dalam TRIPS. Untuk memenuhi komitmen tersebut, Indonesia telah membuat perubahan-perubahan dalam bidang legislatif, administratif, tata cara pengadilan dan penegakan hukum. Tulisan ini juga membahas permasalahan di seputar pelaksanaan perubahan-perubahan tersebut.
PERJANJIAN KERJASAMA ANTARA PEMERINTAH DAN SWASTA DALAM PENYEDIAAN INFRASTRUKTUR PUBLIK
Authors: Asikin Zainal
Published: August 2023

This research identifies several regulations related to public-private partnership (PPP) agreements such as acts, government regulations, presidential regulations, and local byelaws. We find that in addition to having some legal lacunae, the existing norms are either conflicting or obscure. In practice, this condition opens chance for many interpretation which eventually result in a cornucopia of different variety of inferior regulations. We will show that provisions pertaining to the designation of the contracting parties in a PPP and its dispute settlement are conflicting. Penelitian ini berhasil menunjukkan beberapa peraturan hukum yang menjadi payung hukum perjanjian kerjasama antara pemerintah dan swasta, antara lain dalam bentuk undang-undang, peraturan pemerintah, peraturan presiden, dan peraturan daerah. Ternyata masih terdapat kekosongan norma, konflik norma, dan kekaburan norma dalam berbagai peraturan hukum tersebut sehingga menimbulkan berbagai penafsiran dalam praktik, dan pada akhirnya berdampak pada berbagai ragam peraturan. Konflik norma berkisar tentang siapa yang menjadi para pihak dalam perjanjian kerjasama antara pemerintah dan swasta serta bagaimana penyelesaian sengketa atas sengketa hukum tersebut.
ALTERNATIF KEBIJAKAN PERATURAN DAERAH PERSPEKTIF GENDER BAGI BURUH MIGRAN PEREMPUAN DI MADURA
Authors: Rahayu Devi , Munir Mishbahul
Published: August 2023

Problems faced by Women Migrant Worker partly incurred in connection with the position of their woman role that have occurred since the time of recruitment process until departure and when returning back to their home areas. The presence of a legal loophole in the Law 39 of 2004 is one of the problems. The existence of a gender perspective of regional policy is an effort to guarantee the rights of migrant workers and as a solution to problems related to the position of migrant workers. Permasalahan yang dihadapi Buruh Migran Perempuan sebagian besar terjadi sehubungan dengan posisi keperempuanan mereka yang terjadi sejak saat proses rekrutmen sampai pemberangkatan dan ketika pulang kembali ke daerah asalnya. Terdapatnya celah hukum dalam UU No. 39 tahun 2004 merupakan salah satu persoalannya. Adanya kebijakan daerah yang berperspektif gender merupakan upaya untuk menjamin terpenuhinya hak-hak buruh migran.
PENGATURAN PAJAK DAERAH DI PROVINSI DAERAH ISTIMEWA YOGYAKARTA DAN KOTA YOGYAKARTA
Authors: Nugroho Adrianto Dwi , Yuniza Mailinda Eka
Published: August 2023

The enactment of Act Nr. 28 of 2009 on Local Taxes and Local Levies would allegedly pose some juridical impact on local tax collection at the provincial and district/cities throughout Indonesia. The juridical impact would at least occur to local regulations governing local taxes, Regional Government Revenue and Expenditure (APBD), and the oversight of local regulation by the provincial and district/ city governments. This research is a normative-empirical research, which aims to analyse changes of local taxes law in Act Nr. 28 of 2009. This study offers an insight of the impact of this Act on local tax collection in the special province of Yogyakarta. Pemberlakuan UU No. 28 Tahun 2009 tentang Pajak Daerah dan Retribusi Daerah disinyalir akan menimbulkan beberapa dampak yuridis terhadap pemungutan pajak daerah di tingkat provinsi dan kabupaten/kota di seluruh Indonesia. Dampak yuridis tersebut setidaknya terjadi terhadap produk hukum daerah yang mengatur tentang pajak daerah, Anggaran Pendapatan dan Belanja Daerah (APBD), dan pengawasan produk hukum daerah oleh pemerintah provinsi dan pemerintah kabupaten/kota. Penelitian ini merupakan penelitian normatif-empiris, yang bertujuan menganalisis perubahan pengaturan tentang pajak daerah dalam UU No. 28 Tahun 2009, sehingga melalui penelitian ini terlihat dampak yuridis penegakan UU ini pada pengumpulan pajak lokal di Provinsi DIY.
New Issues in Intellectual Property Law in Indonesia
Authors: Hawin M.
Published: August 2023

This article compares the provisions on moral rights in Indonesian Copyright Act, Copyright Bill, and The Berne Convention. The legality of parallel importation and the sui generis protection of traditional knowledge are also observed by referring to the Copyright Bill and Traditional Knowledge Bill. Tulisan ini membandingkan pengaturan mengenai hak moral menurut Undangundang Hak Cipta, RUU Hak Cipta dan Konvensi Berne. Selain itu, tulisan ini juga mengkaji legalitas impor paralel dan perlindungan sui generis terhadap pengetahuan tradisional dengan merujuk kepada RUU Hak Cipta dan RUU Pengetahuan Tradisional.
Globalization and Climate Change Regulations in Indonesia
Authors: Sulistiawati Linda Yanti
Published: August 2023

Globalization is rampant in every aspect of human life. Climate change is a global issue and hence Indonesia must equip itself with sufficient national laws and regulations that are easily implemented. Securing funds from the international community is also a strategy to prepare the nation to face climate change. Globalisasi terjadi di setiap aspek kehidupan manusia. Perubahan iklim adalah isu global sehingga Indonesia harus mempersiapkan diri dengan cara menyusun peraturan perundang-undangan nasional yang dapat diterapkan dengan mudah. Mendapatkan dana bantuan internasional juga merupakan strategi yang dapat diambil untuk mempersiapkan diri menghadapi perubahan iklim.
RECALL ANGGOTA DPR DAN DPRD DALAM DINAMIKA KETATANEGARAAN INDONESIA
Authors: Huda Ni’matul
Published: August 2023

Political parties have the authority to recall the members of parliament, even make his party membership revoked if a member violates the party’s policy. This is because the nomination of members of parliament nominated by political parties. However, the Constitutional Court decision has changed the mechanism of the serial number be a majority vote in determining who sits in parliament. Partai politik memiliki wewenang untuk me-recall anggotanya dari parlemen, bahkan mencabut keanggotaan seseorang dari partainya apabila anggota tersebut melanggar kebijakan partai. Hal ini dikarenakan pencalonan anggota parlemen diusulkan oleh partai politik. Namun, putusan Mahkamah Konstitusi telah mengubah mekanisme nomor urut menjadi suara terbanyak dalam menentukan siapa yang duduk di parlemen.
PELANGGARAN DAN PERLINDUNGAN HUKUM TENAGA KERJA PEREMPUAN DI KABUPATEN MALANG
Authors: Hilmy Umu
Published: August 2023

The number of Indonesian workers who encounter problem abroad continues to increase as the amount of migrant workers shows an exponential growth. The majority group, which is female workers, suffer from economic, psychological, and physical violence. Every effort shall be made to end this condition. Jumlah TKI yang mengalami masalah secara kuantitas dan kualitas meningkat seiring dengan meningkatnya jumlah tenaga kerja yang bekerja di luar negeri. Bentuk pelanggarannya adalah kekerasan ekonomi, psikologi dan fisik. Mayoritas tenaga kerja perempuan yang mengalami masalah menyelesaikannya sendiri dengan berbagai cara.