bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of Hydrogen Peroxide Biosensor Based on Immobilization of Hemoglobin on Screen-Printed Carbon Electrode Modified With Silver Nanoparticles
Authors: Elewi Ali Saad , Wadood Shatha Abdul , Ali Abdul Kareem Mohammed
Published: June 2021

The direct electron transfer behavior of hemoglobin that is immobilized onto screen-printed carbon electrode (SPCE) modified with silver nanoparticles (AgNPs) and chitosan (CS) was studied in this work. Cyclic voltametry and spectrophotometry were used to characterize the hemoglobin (Hb) bioconjunction with AgNPs and CS. Results of the modified electrode showed quasi-reversible redox peaks with a formal potential of (-0.245V) versus Ag/AgCl in 0.1M phosphate buffer solution (PBS), pH7, at a scan rate of 0.1Vs-1. The charge transfer coefficient (Î±) was 0.48 and the apparent electron transfer rate constant (Ks) was 0.47s-1. The electrode was used as a hydrogen peroxide biosensor with a linear response over 3 to 240 ÂµM and a detection limit of 0.6 ÂµM. As a result, the modified biosensor here has exhibited a high sensitivity, good reproducibility and stability.
The Role of Fructophilic Lactic Acid Bacteria in the Restoration of Infected Wounds and IL-17 Level in Rabbits
Authors: Salman Shahad Mansour , Saleh Ghada Mohammed
Published: June 2021

Fructophilic lactic acid bacteria (FLAB) isolated from honeybeeâ€™s nectar stomach represent an important source of antimicrobial substances that has been focused on nowadays. In this study, these FLABs were tested for their antibacterial activity in vivo as well as the detection of Interleukine -17 in the serum of rabbits ingested with FLAB isolates. Fructobacillus fructosus FH1, Fructobacillus fructosus FH8 and Lactobacillus kunkeei SHGH-7 FLAB isolates were used against wound infections caused by Pseudomonas aeruginosa and Staphylococcus aureus (MRSA) in rabbit skin . Enzyme linked sorbent immunoassay (ELISA) was used to detect the levels of Interleukine-17 in the sera of rabbits ingested with these three FLAB isolates. The results showed that the time of wound healing process was shorter in the FLAB treated wounds when compared to control untreated wounds with a significant difference at pâ‰¤0.01. Histopathological examination of wounds treated with FLAB isolates showed normal thickness in skin layers with no pathological effect, as well as tissue repair and presence of new blood vessels when compared to pathogen groups that were infected with pathogenic bacteria without any treatment, which showed hyperplasia with necrosis in tissue. Results of the FLAB-ingested groups showed an increase in the level of IL-17 when compared to the control with no statistical significance (Pâ‰¤0.05). To the best of our knowledge, this is the first study on using FLAB microorganisms in the treatment of infected wounds.
Detecting the Possibility of Soil Pollution with Radon Emissions for an Area Located within Baghdad University Campus- AL-Jadiriyah
Authors: Al-Khafaji Wadhah Mahmood Shakir , Mehdi Ruwaida Tariq , Rejah Basim Khalaf
Published: June 2021

This research deals  with the detection of possible surface soil pollution by radon emissions for an area located inside the university of Baghdad campus at AL-Jadiriyah / Baghdad. The area is about 5625 m2 and located near the College of Science for Women. The area used as construction rubbles dump yard in the past, while recently it is covered with Silty - Clayey soil furnished with grass and used as a playground. A surface survey performed on October 2018 by gridding the area into 36 stations where surface radiometric pollution readings recorded and soil samples collected by using an auger for the top 30 Cm which represents the root zone of the area. Soil samples tested in the laboratory by using can technique with CR-39 type track detectors, while surface readings performed by using a portable Geiger counter device.  Soil surface readings and laboratory analysis results were processed by computer in order to draw contour maps which showed the variation of radon emission anomalies across the area. The aim behind this processing and interpretation is to provide an evaluation for the health environmental impact related to the radioactivity of the top soil and the area surface. The results of this study showed that radon emissions were below the standard limits and this makes it possible to invest the area for future human housing and other activities.
Strongly and Semi Strongly E_h-b-Vex Functions: Applications to Optimization Problems
Authors: Majeed Saba Nasser
Published: June 2021

In this paper, we propose new types of non-convex functions called strongly --vex functions and semi strongly --vex functions. We study some properties of these proposed functions. As an application of these functions in optimization problems, we discuss some optimality properties of the generalized nonlinear optimization problem for which we use, as an objective function, strongly --vex function and semi strongly --vex function.
The Use of Ground Penetrating Radar to Assess the Concrete
Authors: Mohamed Anas A. , Jawad Laith A. , Mahmood Faleh H.
Published: June 2021

Ground Penetration Radar (GPR) is a modern and promising geophysical technique for near-subsurface exploring and observing because of its characteristic working scheme (instantaneous underground radargram displaying and subsurface features preserving during the detection tests). In this technique a very high and/ or ultra-high electromagnetic radiation frequencies were utilized to be transmitted to the targeted underground area, then the reflected ones which occur because of the sudden changes in the medium electric properties or texture would be recorded and processed to achieve the final GPR radargram.

     The main goal of this study is to find out the GPR radiation extension which is suitable for concrete or rebar tiling identifying and measuring in addition to discover the cracks in the concrete walls, the minor goal is studying the effect of GPR device parameters changing on produced radar imagery and identifying the most effective parameter settings for concrete buildings cornerstone locating and wall cracks detection. These parameters are (radiation phase velocity m/sec., frequency coding or sampling, time windows in nano sec., and background removal for unwanted layers removing). The study executed using 1000 MHz antenna on 12 paths and clearly showed that the most important filter/ and or parameter in concrete sites locating and mapping is the "background removal" filter, while other parameters were image improvement ones or sometimes had a negative role in detection procedure.
Phylogenetic tree analysis based on the 16S sequence alignment for Klebsiella spp. isolated from different sources
Authors: Abdul Qader Mustafa Basil , AlKhafaji Marwa Hameed
Published: June 2021

16S ribosomal RNA (16S rRNA) gene sequences used to study bacterial phylogeny and taxonomy have been by far the most common housekeeping genetic marker utilized for identification and ancestor determination. This study aimed to investigate, for the first time, the relationship between Klebsiella spp. isolated from clinical and environmental samples in Iraq.

     Fifty Klebsiella spp. isolates were isolated from clinical and environmental sources. Twenty-five isolates were collected from a fresh vegetable (Apium graveolens) and 25 from clinical samples (sputum, wound swab, urine). Enteric bacteria were isolated on selective and differential media and identified by an automatic identification system, vitek-2. The total DNA was extracted and PCR amplified for selected isolates. The 16S rRNA gene was amplified by using the universal primer 27F (5'- AGAGTTTGATCCTGGCTCAG- 3') and 1492R (5'- GGTTACCTTGTTACGACTT- 3â€™). The 16SrRNA gene sequence was analysed among some local isolates, and the results were compared with the standard data of similar registered strains in NCBI. The most common species of Klebsiella was Klebsiella pneumoniae pneumoniae (Kpp), followed by Klebsiella pneumoniae ozaenae (Kpo) and Klebsiella oxytoca (Ko). The results of the identification of species and sub species by using the  biochemical test (vitek-2) were more precise than those obtained by the use of the universal primer.Phylogenetic tree strategies have clearly indicated a relatively close similarity amongst all analysed Klebsiella isolates and revealed the intra-species genetic distance between the individual isolates of the Klebsiella spp. In conclusion, our results revealed the main advantage of using universal primers for the identification of Klebsiella spp. and their root from nature.
Impact of Exercise Training on Hematological Outcomes Following Hematopoietic Cell Transplantation: A Scoping Review
Authors: Aziz Joseph Aziz , Smith Chloe , Slobodian Mitchell , Du Iris , Shorr Risa , De Lisio Michael , Allan David S.
Published: June 2021

Purpose: Hematopoietic cell transplantation (HCT) is associated with significant risk prior to hematopoietic engraftment. Endurance exercise can modify the bone marrow microenvironment, alter hematopoiesis and accelerate hematopoietic regeneration in mouse models of transplantation.

Methods: A systematic review was conducted to clarify the impact of exercise on clinically relevant hemato-logical outcomes in patients following HCT.

Results: A systematic search of the literature identified 13 studies (total of 615 participants; 313 in study arms). Studies included exercise regimens that were primarily low-to-moderate intensity. A total of five studies re-ported on engraftment and length of stay, which were largely unchanged with intervention. Rates of graft-ver-sus host disease were reported in six studies whereas red cell and platelet transfusion needs were reported in four studies, neither of which was different with exercise. Survival was reported in four studies and was significantly improved by exercise in one study.

Conclusions: Exercise in patients receiving HCT appears feasible and safe. Heterogeneity in type and intensity of exercise was observed and few studies examined high intensity exercise. Outcome reporting was inconsis-tent regarding transplant-related outcomes. Standardized hematological outcome measures are needed to clarify the impact of higher intensity exercise on HCT.
Clinical Public Health - Published 44(2) June 2021
Authors: Young Kue , Ramsay Tim
Published: June 2021

In this issue, Bernard Choi and colleagues have presented their vision of clinical public health as an approach to address complex health issues in our health system. To help stimulate discussion, CIM invited commentaries from two distinguished scientists to present their views on the concept. We hope this discussion will ultimately guide the direction public health will follow.
El estrés académico y resiliencia en madres universitarias colombianas con y sin apoyo institucional en el cuidado de sus hijos
Authors: Osorno-Foronda Maria Alejandra , De Hoyos-Rivera Mileth , García-Vallejo Maria Alejandra , Cordoba-Sanchez Verónica
Published: June 2021

Son cada vez más las mujeres que asumen simultáneamente los roles de madre y estudiante en el ámbito universitario; lo cual puede hacerlas vulnerables a factores que obstaculizan su adecuado proceso académico. A través de un estudio cuantitativo, con un diseño de casos y controles, se analizó la asociación entre el estrés académico y la resiliencia en una muestra de 52 madres de dos instituciones universitarias colombianas: el Instituto Tecnológico Metropolitano y la Institución Universitaria de Envigado, de las cuales, la primera cuenta con un aula pedagógica de apoyo en el cuidado de los hijos de las estudiantes y se constituyó en el grupo de casos y la segunda no cuenta con este beneficio, conformando el grupo de control. Para la recolección de datos se aplicó un cuestionario sociodemográfico, la Escala de Resiliencia SV-RES y el Inventario de Estrés Académico SISCO. Se halló que el grupo de control tuvo niveles superiores de estrés psicológico y presentó una asociación negativa entre el estrés psicológico, comportamental y físico y el nivel total de resiliencia.
Official and unofficial employment of visually impaired people (on the example of Khabarovsk)
Authors: Trinadtsatko Anton Aleksandrovich
Published: June 2021

The object of this research is visually impaired people as an invariant of disabled people of discredited stigmatype. The subject of this research is the employment of visually impaired people of working age, members of the Khabarovsk local organization of All-Russia Association of the Blind (VOS). The goal of this work is determine the level of official and unofficial employment of visually impaired people and the factors affecting it. The author notes that despite positive changes taking place in the Institution of employment assistance for people with disabilities, the representatives of nosology of the disabled people with discredited stigmatype are still being discriminated in the job market, finding jobs in their close social circle or working in places that are not adjusted to their needs. It is established that visually impaired people are actively engaged into the sphere of social and labor relations, the great majority of them have work experience in the status of a visually impaired person in jobs that are not adjusted to their specificities. People with disabilities more often are employed officially. Social and labor integration of people with health limitations first and foremost depends on their level of education, qualifications and work experience, as well as on the age of being registered as a disabled person. The key motive for employment is the need for broadening social interactions. The novelty of this work consist in revealing the structure of official and unofficial employment of visually impaired people in accordance with disability groups, age, level of education, and other characteristics, as well as in outlining the factors, conditions, and motives that affect the their employment status, and obstacles for their promotion. The scientific relevance of the acquired results consists in expansion and specification of a range of issues that require closer joint attention of the members of the project, academic, and practice-oriented communities, as well as in highlighting the key aspects of employment assistance for people with disabilities of discredited stigmatype.
A brief overview of the reception of “The Tale of Igor's Campaign”
Authors: Li Ziwei
Published: June 2021

The subject of this research is the process of reception of “The Tale of Igor's Campaign” in mainland China. The analysis of China’s historical conditions and comparison of the statistics at different periods indicate changes in the process of reception of Russian literature as a whole, and the Old Russian literary landmark in particular in the course of historical development of Celestial Empire. The novelty of this research is defines by insufficient coverage of the process of reception of “The Tale of Igor's Campaign” in China as a special cultural phenomenon, inseparable from the overall process of cultural and literary development of the country. Reception of the Russian literature is viewed in the socio-historical system, in which it organically interacts with the national culture and literature. The article employs descriptive, conceptual, and comparative-historical methods for solving the scientific task; determines the key stages in the general process of reception of “The Tale of Igor's Campaign” in China; and reveals the peculiarities of each stage with description of the major achievements. The author concludes that for almost two centuries, the Old Russian literary landmark has undergone a propaedeutic reception in China, which gradually intensified after the May Fourth Movement. It experienced stagnation after the first complete translation of the “Tale” into Chinese language, and a breakthrough in the image of this work in modern Chinese science, which currently interprets “The Tale of Igor's Campaign” as a literary-historical text.
Postmeniscectomy osteonecrosis of the knee: A case report and literature review
Authors: Alomar Abdulaziz Z
Published: June 2021

Postarthroscopic osteonecrosis of the knee (PAONK) is a rare form of osteonecrosis for which the pathogenesis and etiology remain poorly understood; however, there is evidence of a close association with meniscectomy in most PAONK cases. Based on this evidence, postmeniscectomy osteonecrosis of the knee (PMONK) has been suggested as a new category. As early diagnosis and appropriate treatment can improve prognosis, there is a need to differentiate PMONK from spontaneous osteonecrosis of the knee (SONK). This differentiation is specifically important in the Middle East and Arab countries where PMONK and PAONK have not been reported before, which could have resulted from under-reporting or under-diagnosis. To address this gap, we present a case of PMONK from this region and discuss assessment findings and treatment relative to the current evidence.
Comparative analysis of optical coherence tomography data in recurrent macular rupture after using various techniques for its blocking
Authors:   Federal state budgetary institution «National Medical and Surgical Center named after N.I. Pirogov» of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation, Larina E.A. , Fayzrakhmanov R.R. ,   Federal state budgetary institution «National Medical and Surgical Center named after N.I. Pirogov» of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation, Pavlovskii O.A. ,   Federal state budgetary institution «National Medical and Surgical Center named after N.I. Pirogov» of the Ministry of Healthcare of the Russian Federation, Moscow, Russian Federation
Published: June 2021

Purpose. To assess the morphological parameters of the central retina in different groups with unblocked macular rupture after primary surgery for macular rupture (MR). Material and methods. This study involved 32 patients (35 eyes), including 19 women, 13 men. 3 groups were formed according to the principle of primary surgery. All patients underwent standard ophthalmological examinations, as well as optical coherence tomography (OCT). Results. According to OCT data, the morphological and functional parameters were different depending on the primary method of surgical treatment. The diameter of the MR along the large and small radius is the biggest in the 3rd group. The area of edema in the analysis of various methods of surgical treatment did not differ statistically. Conclusion. The functional parameters of the central part of the retina do not depend on the initial method of surgical intervention. The use of mechanical action on the retina causes rigidity of the edges of the macular rupture, and when using an introverted flap, the small and large diameters of the macular rupture remain minimal, in contrast to the use of platelet mass and mechanical closure of the MR. Key words: macular hole, platelet rich mass, introverted flap, mechanical closure, rigid.
Features of choroidal blood flow and their influence on formation of peripheral retinal degenerations in school-age children with undifferentiated connective tissue dysplasia
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Li V.V.
Published: June 2021

Purpose. To study choroidal thickness (CT) and assess its effect on frequency of occurrence dangerous types of peripheral retinal degenerations (PRD) in school-age children with myopia associated with undifferentiated connective tissue dysplasia (UCTD). Material and methods. The object of study was 62 children (124 eyes) aged 10–15 years (mean age 12.3±0.8 years) with progressive myopia associated with moderate (48 people, 77.4%) and pronounced (14 people, 22.6%) degree of UCTD. Special ophthalmologic examination included macular imaging by optical coherence tomography (RTVue 100, «Optovue», USA) to measure CT. Diagnostic criteria by T.M. Milkovskaya-Dimitrova et al (1987) were used to identify phenotypic characters of UCTD. Results. Comparative characteristic of CT in macula showed high (p <0.05) relationship between the blood-filled of choroidal vessels and degree of UCTD. Analysis frequency of occurrence of PRD depending on CT demonstrated that against the background accumulation of phenotypic characters of UCTD increase in frequency of occurrence of PRD was observed. Statistical analysis confirmed presence of significant negative correlation between decrease CT and increase in incidence of prognostically dangerous forms of PRD. Conclusion. It was found that in school-age children with myopia with increase degree of UCTD, CT decreases. With choroidal thinning in children with myopia associated with UCTD, the frequency of occurrence dangerous forms of PRD increases. The research results are of clinical importance for the development of rational approaches to clinical examination and treatment children with school myopia with clinical signs of UCTD. Key words: progressive myopia, undifferentiated connective tissue dysplasia, choroidal thickness, peripheral retinal degeneration, rhegmatogenous retinal detachment.
Morphometric assessment of the state of the choroid in patients with anterior uveitis associated with the HLA-B27 Antigen
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Udovichenko E.V. , Sorokin E.L. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation,   Far Eastern State Medical University, Khabarovsk, Russian Federation, Danilova L.P. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation,   Postgraduate Institute for Public Health Workers, Khabarovsk, Russian Federation
Published: June 2021

Purpose. To assess the state of the choroid in patients with anterior uveitis associated with the HLA-B27 Antigen, without ophthalmoscopically detectable lesions of the macular zone. Material and methods. 24 patients with acute anterior uveitis associated with HLA-B27 Antigen, without ophthalmologically detectable changes in the macular zone. The average age of the patients was 39.02±13.76 years. There were 16 men and 8 women. Maximum corrected visual acuity ranged from 0.1 to 0.5. The level of intraocular pressure according to Maklakov varied from 15 to 22 mm Hg. The subfoveal choroidal thickness (SCT) was determined using an optical coherence tomograph in comparison with paired intact eyes before treatment and 2 weeks after its initiation. Results. The initial values of the SCT index in the main group varied from 337 to 371 µm, averaging 354±8 µm. This is statistically significantly higher than in intact paired eyes (255±7 µm; from 246 to 268 µm; p<0.001). 2 weeks after the start of treatment, the SCT index in the main group was 268±10 µm, which was statistically significantly lower than the initial values in this group (p<0.001). Conclusion. A statistically significant increase in SCT was revealed in the eyes of patients with acute anterior uveitis. 2 weeks after the start of treatment, the SCT index statistically significantly decreased to 268±10 µm, which did not statistically significantly differ from that of the intact eye. Key words:anterior uveitis, HLA-B27 Antigen, subfoveolar thickness of the choroid.
Extraesophageal masks of gastroesophageal reflux disease: frequency, features of diagnosis and preparation of patients for ophthalmic surgery
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Filimonova E.E. , Pavlyushchenko L.V. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Esina M.A. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation
Published: June 2021

Purpose. Evaluation of the frequency of gastroesophageal reflux disease (GERD) in the structure of somatic diseases of patients admitted to ophthalmic surgery, features of the manifestation and difficulties in diagnosing. Material and methods. The analysis of the preoperative state of 1213 patients with pathology of the gastrointestinal tract (GIT) was carried out. The frequency of GERD with typical and extraesophageal manifestations was studied. The assessment of the adequacy and effectiveness of drug therapy is given. Results. Pathology of the gastrointestinal tract in the structure of nosological forms of somatic diseases of patients entering ophthalmic surgery is 5–6%. GERD accounts for 30% of their number. Typical clinical manifestations of GERD occurred in 287 patients (79.1%). Of these, 203 people. (70.7%) were able to compensate for the disease, received adequate therapy with proton pump inhibitors. In 84 patients (29.3%), heartburn and epigastric discomfort persisted. In 76 patients (20.9%) with GERD, its extraesophageal manifestations were revealed. Have 29 people. (38%) they manifested themselves in the form of retrosternal pain. A paroxysmal dry cough, asthma attacks arising after eating, the appearance and aggravation of nocturnal symptoms of bronchial asthma disturbed 35 people (46%). Complaints of burning tongue, hoarseness, soreness when swallowing, sore throat, periodic laryngospasm were observed in 12 patients (16%). Conclusion. GERD takes the leading place among diseases of the upper gastrointestinal tract (more than 30%). About 21% are atypical manifestations of GERD. The most clinically significant among them, limiting the possibility of conducting planned surgical treatment, are cardiological and pulmonary masks. Modern etiopathogenetic treatment of GERD makes it possible to effectively stop the symptoms of the disease, avoid polypharmacy and unreasonable refusal in planned surgical treatment for patients with ophthalmic diseases. Key words: gastroesophageal reflux disease, extraesophageal manifestations, ophthalmic surgery.
About the rare cases of Vogt–Koyanagi–Harada syndrome
Authors:   Ufa Eye Research Institute, Ufa, Russian Federation, Babushkin A.E.
Published: June 2021

Diagnosis of the classic form of Vogt–Koyanagi– Harada syndrome, as a rule, does not present special difficulties. The latter arise when the syndrome develops atypical. The cases described in the article indicate that the specific extraocular symptoms help in the timely diagnosis of the Vogt–Koyanagi–Harada syndrome and may appear long before the development of eye damage in the form of bilateral uveitis. Even in their absence, the presence of bilateral panuveitis on the background of minor meningism with indistinct neurological symptoms and insignificant pleocytosis in the cerebrospinal fluid made it possible to make a diagnosis correctly and start a successful pulse-therapy with steroids. In the development of complications, particularly, in complicated cataracts, the functional results after its removal by phacoemulsification with intraocular lens implantation can be quite successful on the background of adequate corticosteroid therapy. Key words: Vogt–Koyanagi–Harada syndrome, atypical course, clinical rare cases, extraocular symptoms, bilateral uveitis.
Assessment of indicators of quality of life and vision in patients with posterior segment of the eye pathology
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Orenburg Branch, Orenburg, Russian Federation, Chuprov A.D. , Lositsky A.O. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Orenburg Branch, Orenburg, Russian Federation, Trubnikov V.A. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Orenburg Branch, Orenburg, Russian Federation, Firsov A.S. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Orenburg Branch, Orenburg, Russian Federation
Published: June 2021

Purpose. Comparative analysis of the quality of life profiles in patients with various vitreoretinal diseases. Material and methods. The study included 76 patients with established diseases of the retina and vitreous body aged 17 to 82 years, of which 25 were men and 51 were women. All participants were interviewed using a special questionnaire assessment of vision Visual Functioning Questionnaire 25 (VFQ-25). Quantitative data are processed using descriptive statistics and presented as medians and quartiles. The reliability of differences between patients from different observation groups was confirmed by nonparametric statistics (the Mann–Whitney test). The reliability of the differences was considered established at p<0.05. Results. The results of patients' subjective assessment of various social aspects of their life activity are shown. The results of a comparative assessment of quality of life indicators depending on the diagnosis are given. Conclusion. The quality of life profile of patients with vitreoretinal pathology is characterized by a low assessment of patients ‘General health status and a high level of dependence on external assistance. Patients experience significant difficulties when driving a car. There is also a low level of role difficulties reflecting the individual's adaptive reserves in society. There were significant differences in the levels of assessment of quality of life indicators by respondents with various vitreoretinal diseases on the scales: «General health», «near visual function». Key words: quality of life, diseases of the posterior segment of the eye, VFQ-25 questionnaire, ophthalmological patients.
Organization and implementation of emergency ophthalmic surgical assistance in a specialized ophthalmic clinic during the Pandemic period COVID-19
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Mashchenko N.V.
Published: June 2021

Purpose. Evaluation of the frequency, structure and severity of the eye injuries, the effectiveness of the implementation of primary surgical treatment (PST) and the outcomes of their surgical treatment. Material and methods. In just a period from the end of March to December 2020, in the Khabarovsk branch the S. Fyodorov Eye Microsurgery Federal State Institution received 51 patients with various as penetrating (48 eyes) and imperriburing injuries of the eyeball (3 eyes). Their age varied widespread from 5 to 56 years (on average 35.5 years). Men were dominated among them – 44 people, women – 7 people. Adults were 49 people, children – 2 people. Results. Under the conditions of obtaining penetrating injuries, household injuries were isolated – 33 eyes (65%), production – 15 eyes (29%). The contusion injury of the eye was criminal, which was 6% (3 eyes). According to the localization of penetrating injuries or the impact of mechanical damage, they were presented: corneal wounds – 12 eyes, rootless – 17 eyes, scleral – 18 eyes. In 13 eyes, there was an intraocular foreign bodies (IFB). Conclusion. Thus, for the period from April to December 2020, in our branch, PST eyes were performed about 47 heavy penetrating injuries, including the introduction of IFB in 13 eyes, 4 eyes with extensive damage to conjunctiva. Among the victims were 49 adults and 2 children. Key words: penetrating eye wound, intraocular foreign body, microgery surgery, traumatic retinal detachment.
Analysis of the structure of ophthalmological pathology of outpatients in the treatment and diagnostic department
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Romanova A.V. , Burya R.A. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Pilipenko A.D. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Sorokin E.L. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation,   Far Eastern State Medical University, Khabarovsk, Russian Federation
Published: June 2021

Purpose. Clinical analysis of the nosological structure of ophthalmologic pathology in patients who applied to the treatment and diagnostic department (TDD) in 2020. Material and methods. The article provides an analysis of the number of patients who applied to the TDD of the Khabarovsk branch of the S. Fyodorov Eye Microsurgery Federal State Institution for the period from the beginning of January to the end of December 2020 (continuous sampling method). An assessment of their age and gender composition is given, an analysis of the nosological structure of ophthalmopathology in the patients who have applied, its stage, is carried out, a comparison is made with similar data from five years ago. Results. In the structure of ophthalmic pathology, there was a high turnover rate of patients with the presence of various types of ametropia, as well as for the purpose of its surgical correction. A large number of patients with socially significant types of pathologies: cataracts, glaucoma, acquired diseases of the macular region, vascular diseases of the retina, requiring highly specialized surgical and conservative treatment. The analysis of the results of the work of the TDD showed a high percentage of detection of eye diseases, as well as for the first time detected serious pathology, achieved with the help of complex modern diagnostic methods. Conclusion. In 2020 8 851 patients with various ophthalmic pathologies were examined. In comparison with the five-year data, the volume of applications to LDOs increased significantly by 42%. Key words: ophthalmopathology, refractive error, cataract, glaucoma, medical and diagnostic department.
Relationship between duration of antihypertensive regimen and incidence of dry eye syndrome in patients with primary open-angle glaucoma
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Pilipenko A.D. , Burya R.A. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Romanova A.V. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation
Published: June 2021

Purpose. To study the incidence of dry eye syndrome (DES) in patients with primary open-angle glaucoma (POAG), depending on the duration of the use of local antihypertensive therapy. Material and methods. The material for the study was patients who were examined in the treatment and diagnostic department of the Khabarovsk branch the S. Fyodorov Eye Microsurgery Federal State Institution with a confirmed clinical diagnosis of POAG. The main group included 45 patients with a duration of antihypertensive therapy of 1 month or more. The comparison group consisted of 15 patients with newly diagnosed POAG. The period of use of antihypertensive therapy in them did not exceed one month. Depending on the experience of using antihypertensive therapy, the patients of the main group were divided into 3 subgroups. All were questioned using the DEQ-5 dry eye questionnaire, Schirmer I, II and Norn's tests, objective examination of the anterior segment of the eyes. The analysis of the detection and severity of DES among patients with POAG was carried out, taking into account the experience of using the antihypertensive regimen. Results. According to the questionnaire, 26 patients (58%) of the main group presented complaints typical of DES, while in the comparison group only 3 patients (20%) presented them (p<0.05). There was also a tendency towards a decrease in the total and main type of tear production in the main group according to the results of Schirmer's tests I and II – 10.9±1.04 mm and 7.7±0.48 mm versus 13.9±2.5 mm and 10, 2±2.1 mm in the comparison group (p>0.05). The stability of the tear film, according to Norn's test, also differed: 8.2±0.35 sec. and 9.5±1.8 sec. in the main and comparison group, respectively (p> 0.05). Conclusion. The initial symptoms of xerosis of the ocular surface are recorded in the period from 1 to 3 years from the beginning of the use of antihypertensive drugs and increase in proportion to the increase in the length of the disease. Key words: dry eye syndrome, glaucoma, antihypertensive therapy.
The effectiveness of descemethogoniopuncture depending on the timing of its implementation after microinvasive non-penetrating deep sclerectomy in patients with glaucoma
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Sorokin E.L. ,   Far Eastern State Medical University, Khabarovsk, Russian Federation, Postupaeva N.V. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation
Published: June 2021

Purpose. Evaluation of the efficacy of descemethogoniopuncture (DGP) at various times after microinvasive non-penetrating deep sclerectomy (MNPDS) in patients with glaucoma. Material and methods. The analysis of the results of DGP in 64 eyes of patients with primary open-angle glaucoma after previously performed MNPDS. According to the timing of DGP after MNPDS, the patients were divided into 3 groups. In the 1st group BPH was performed after 1–2 months (22 eyes), the 2nd group – after 3–4 months (21 eyes), the 3rd group after 5–6 months (21 eyes). The follow-up period was 1 year. Results. The level of intraocular pressure before DGP averaged 15.1±0.6 mm Hg in group 1, 17.5±0.9 mm Hg in group 2, and group – 18.6±0.7 mm Hg. After DGP, 13.1±0.4 mm Hg, 14.6±0.7 mm Hg, 16.1±0.5 mm Hg respectively. According to ultrasound biomicroscopy, the highest and extended intrascleral cavities and tunnels, as well as a thin loose trabeculodescemet membrane (TDM), were observed in the eyes of the 1st group. With an increase in the time after MNPDS, there was a compaction of TDM, a decrease in the height and length of the intrascleral cavity and tunnels. 12 months after DGP, the most pronounced antihypertensive effect without antihypertensive therapy occurred in group 1 – 55% of cases compared with groups 2 and 3 (33% and 14% respectively). Conclusion. The greatest efficiency was shown by performing DGP within 1–2 months after MNPDS, which is associated with the minimum development of proliferative processes in the intrascleral outflow tract in the early stages after this operation. Key words: descemethogoniopuncture, microinvasive non-penetrating deep sclerectomy, intraocular pressure, hypotensive effect, glaucoma.
The structure of the clinical variety of macular pathology in patients of diagnostic department
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Zhazybaev R.S. , Zhirov A.L. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Sorokin E.L. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation,   Far Eastern State Medical University, Khabarovsk, Russian Federation
Published: June 2021

Purpose. To study the frequency and nosological structure of concomitant macular pathology in patients admitted for ophthalmic surgery. Material and methods. A study of the state of the macula was carried out in 337 eyes of 170 patients who underwent a diagnostic examination in the Khabarovsk Branch the S. Fyodorov Eye Microsurgery Federal State Institution in 2020. The patients' age was 58±15.2 years. The selection criterion was sufficient transparency of the optical media for viewing the macular zone. An in-depth examination of the macular zone was carried out using a forehead binocular reflex-free ophthalmoscope (Heine OMEGA500, Germany) and a non-contact lens (VOLK Double Aspheric 20D, USA), as well as optical coherence tomography (Cirrus HD-OCT 5000, «Carl Zeiss», Germany). The proportion of macular pathology among the patients who applied, the frequency and severity of its individual nosological forms were evaluated. Results. Various macular pathologies occurred in 28.2% of cases. Age-related macular degeneration (AMD) (47.9%) and epiretinal fibrosis (27.1%) accounted for a significant share in the structure of macular pathology. The frequency and structure of macular pathology in patients with age-related cataracts was analyzed. The incidence of macular pathology in them was 45.1%, of which AMD was detected in 65.2% of cases, epiretinal fibrosis – 7.8%. Conclusion. Among the group of patients selected by the method of continuous sampling with various ophthalmic surgical pathologies, 28.2% had various pathologies of the macular zone. The most common macular pathology occurred in the age group from 45 to 59 years old, accounting for 56.2% of cases. In the nosological structure of macular pathology, the share of AMD and epiretinal fibrosis prevailed. Key words: macular pathology, age-related macular degeneration, epiretinal fibrosis.
Results surgical treatment of rhegmatogenous retinal detachment and macular hole
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk Branch, Khabarovsk, Russian Federation, Zhigulin A.V.
Published: June 2021

Purpose. Analysis of functional and anatomical results surgical treatment of retinal detachment and macular hole (RDMH) with internal limiting membrane (ILM) peeling and silicone tamponade. Material and methods. Analysis of results surgical treatment of 17 patients (17 eyes) with RDMH was carried out. Disease duration ranged from 2 weeks to 3 months. Visual acuity before surgical treatment ranged from no light perception to 0.05 (on average 0.01±0.02). All patients underwent endovitreal surgery with ILM removal. Then retinal holes were localized at periphery with further endolaser coagulation or cryocoagulation and silicone oil (5700 cSt) tamponade. Results. Retinal adhesion was noted in all eyes after primary surgery. Closure of hole was successful in 16 patients. After operation, visual acuity improved in all patients, averaging 0.11±0.09. Conclusion. Vitrectomy with IPM removal and silicone oil (5700 cSt) tamponade in treatment of RDMH made it possible to achieve reattachment of retina in 17 patients, complete closure of macular hole in 16 of 17 patients. One patient, according to optical coherence tomography, showed decrease diameter of macular hole after 12 months. Positive functional effect was achieved in increase visual acuity to average of 0.15±0.15 after 12 months. Key words: retinal detachment, macular hole, vitrectomy, internal limiting membrane removal, silicone oil tamponade, visometry, optical coherence tomography.
Para além das antinomias
Authors: Michetti Miqueli
Published: June 2021

O artigo analisa alguns dos temas centrais dos trabalhos de Renato Ortiz sobre o tema da globalização, com foco nas relações entre cultura e mundialização. Após discutir o ambiente teórico diante do qual o autor estabelece suas reflexões e a postura epistemológica que adota, o texto se volta Ã  sua compreensão original da problemática das relações entre cultura e economia no mundo contemporâneo. Na sequência, delineia-se uma linha de continuidade entre seus trabalhos sobre identidade nacional e seus estudos sobre o que denomina de modernidade-mundo, para destacar a particularidade de suas elaborações sobre as questões da identidade e da diversidade cultural. Ao final, são sublinhadas algumas das principais contribuições legadas pelo autor, a saber, a atenção Ã  questão do poder, a complexidade necessária ao empreendimento crítico, o pensamento relacional, a superação do culturalismo e a apurada compreensão sociológica do presente histórico.
Diante da grande ferida
Authors: Gayão Nicolau
Published: June 2021

A obra e vida de Frantz Fanon ”“ incluindo a publicação recente de textos até então inéditos e ainda pouco estudados, como suas peças e cartas ”“ são analisadas com o intuito de reconstruir o seu conceito de amor. A partir de sua crítica Ã s formas raciais e patriarcais de amor e da sua análise da violência colonial, o ensaio argumenta que a noção fanoniana de amor, elaborada numa linguagem ética e filosófica, pode ser entendida como o movimento do Eu em direção a Você, que almeja tornar real a possibilidade de sua existência para que todos possamos viver; e como uma forma de relação humana ligada profundamente com a escrita e com a luta política por libertação.
Lack of Native Hawaiian Neurologists and Disparities in Care for Native Hawaiians in Hawaiʻi
Authors: Smith Maiya , Tse Christina , Fancher Nicholas , Hiroi Ryoko , Harris William , Kutlu Selin , Anzai Nicole , Miura Heather , Chang Bryce , Miles Douglas
Published: June 2021

Introduction: In Hawaiʻi, there are 367,000 Native Hawaiian and Pacific Islanders. Native Hawaiians experience health disparities in a variety of conditions, including stroke, diabetes, and cancer.  Ethnic minorities are underrepresented among physicians; this lack of physician-patient racial concordance may contribute to the disparities, as recent studies suggest that racial discordance resulted in poorer healthcare quality. This study aims to assess the current status of neurological health disparities in the Native Hawaiian population in Hawaiʻi, with a focus on identifying neurologist ethnic representation, neurological diseases, and healthcare-related challenges disproportionately affecting Native Hawaiians. Methods: An anonymous survey on physician’s attitudes and practice was emailed to all neurologists in the Hawaiʻi Neurological Society from February 2019 to June 2019. Findings: Twenty-three full responses and one partial response was received. No participants self-identified as Native Hawaiian nor did they know of any Native Hawaiian neurologists in Hawaiʻi, yet all who completed the survey reported treating Native Hawaiians in their practice (n = 23), which identifies a gap in Native Hawaiian representation in the field of neurology in Hawaiʻi. In addition, majority of participants perceived that Native Hawaiians are disproportionately affected by neurological diseases and have difficulty accessing neurology services and obtaining quality care. Conclusions: Future focus on creating opportunities to improve racially discordant physician-patient relationships and to increase Native Hawaiian representation in neurology may help narrow the gap in health disparities experienced by Native Hawaiians.
Is parent education protective of mental wellbeing in Pacific young people? A cohort study of mental health and census data in Aotearoa/New Zealand’s integrated data infrastructure.
Authors: Kokaua Jesse , Jensen Seini , Theodore Reremoana , Bowden Nicholas , Blakelock Russell , Sorensen Debra , Jensen Wilmason , Richards Rosalina
Published: June 2021

Aim: The aims of this paper are to quantify the impact of parental education on the five-year incidence of mental health conditions (MHC) in Pacific young people and to investigate the influence of other factors.
Method: The analyses in this paper used data extracted from Aotearoa/New Zealand’s Integrated Data Infrastructure (IDI). Data relating to 383,595 young people (48,768 Pacific), identified in the 2013 Census, aged 12-24 years, and their parents’ were used. Logistic regression models were used to investigate the incidence of children with MHC from 2013-2018.
Results: Mental health conditions were identified in one of five Pacific young people. Irrespective of ethincity, increased parental education was associated with decreased MHC. However, the association was only significant for those in specialist mental health care (OR=0. 897, 95%CI:0.881-0.913) but not for those seen in other health settings (OR=0. 989, 95%CI:0.974-1.004). The association, for specialist settings, was not mediated by the contribution of other factors (OR=0.941, 95%CI:0.926-0.958). However, increased parents education with the addition of social, cultural and economic advantages the number of Pacific children seen in the specialist mental health setting could be nearly halved.
Conclusion: The findings show that a parental educational advantage exists for children who access specialist mental health care. However, there are more complex but far greater opportunities for the health of Pacific families if a coordinated education, housing, employment and health solution were possible. The gains from a multi-disciplinary Pacific solution exist in terms of reduced severity for and level of care to Pacific children with MHC.