bluuebunny/crossref_metadata_2025 huggingface dataset:
Not just an environment: Role and significance of ruins in 17th c. Italian art through the example of Viviano Codazzi
Authors: Broli Costanza
Published: September 2024

The main purpose of this brief article is to trace some of the paths which classical architectural elements have followed during 17th c. in art, especially within easel paintings. Since their first appearance, ancient monuments have always had an important role as iconographical elements, but, as time went by, their function within the artwork changed, and so their meaning: the 17th c. is probably a period when this phenomenon is the easiest to observe. This review of some of Viviano Codazzi’s works provides a glimpse of how artists (and by extension, patrons) chose to incorporate ancient and classical elements into compositions, even with clear inconsistencies, not to give them up. The desire to own a representation of antiquities was stronger than rules of logical and historical coherence, so figures and their environment did not always go along, even until the contamination between Christian and classical sphere. The persistence over time of archaeological motifs is not due to creativity laziness or cultural tradition, it happens becausepeople still wanted to watch them and get caught by them. It is not a rational matter; it is a matter of emotions.
Mistress of the poet’s heart: On reading Lesbia’s iconography
Authors: Maria Łajkosz Roksana
Published: September 2024

This paper takes an issue of iconography of Catullus character – Lesbia. It discusses examples of artworks from the 18th and 19th centuries. The study of art pieces’ formal aspects and their comparing analysis with the poetic background are essential to determine and characterise the reception of Lesbia’s motive in art. The discussed theme is also related to the way of her representation. It is seen not only in the context of visual interpretation of poetry but also as referencing to ancient art. The problem with Lesbia’s images is considered on two levels. On the one side, it is connected with Catullus’s poems, especially Carmina 2 and 3. Two types of her images appear – “playing with pet sparrows” and “weeping over sparrow death”. On the other side of the artwork two ways of her depiction are visible. These are with Catullus’ companion and as single portrayed. They include her images as a child, young girl, and adult woman. Among them Lesbia is presented as indifferent towards lovers’ courting, flirting, or struggling with loss and death. In that context, her iconography is not only a reference to the poetic background but also it is read as an interpretation of her character by Classicism and Neoclassicism artist.
False inspirations: Antique terracotta in 19th c. forms from the collection of Princes Czartoryski Museum
Authors: Gorzelany-Nowak Dorota
Published: September 2024

The article discusses the impact the discovery of terracotta figurines from Tanagra and other ancient towns had on the art world in the 1880s and 1890s. It presents counterfeit artifacts that appeared on the antiquities market at that time and consequently trickled into many collections of antiquities. The analysis of examples taken from the collection of Prince Wladyslaw Czartoryski shows the diversity of ancient inspirations.
The former St. Nicholas Church in Zamość as a Russian “lieu de mémoire”
Authors: Korneluk Paulina
Published: September 2024

This article aims to show the history of the Orthodox church in Zamosc based on the concept of sites of memory developed by Pierre Nora. Zamosc’s church is one of the most important yet enigmatic buildings in the town. It was built for the town’s Greek and Ruthenian communities and for a good number of years was the mainstay of Orthodoxy in the region. At the beginning of the 18th c., it was taken over by the Basilian Order, and in its interiors the statutes of the Synod of Zamosc were signed, which significantly led to the unification of the Latin Church and the Uniate Orthodox Church and the widespread Latinisation of the Eastern Rite. During the Partition period, this church was subjected to ideologisation by the Russians. For them, it was a symbol of disgrace and heresy, just like St. Nicholas’ Church in Brest, where the act of the Union of Brest was signed. The Russians did everything to reverse the memory of the synod and to make the church a new place of consolidation for the local population, as well as for the elites in Russia, who were shown Zamosc and the Chelm Land, of which it was a part, as the eternal part of the Ruthenian lands. The Zamosc Orthodox Church appeared in books, albums and postcards. It was intended both to build communion with Russia and to create a “new Rus” citizen of the Chelm Land.
Case study: lost identity and the New Synagogue in Częstochowa: Architecture of the houses of prayer as contemporary places of non-memory in culturally homogeneous cities
Authors: Morawska Wiktoria
Published: September 2024

The aim of the article is to show the social context of synagogue architecture on the example of the hitherto unexplored New Synagogue in Czestochowa. The analysis is an attempt to show the relationship between the location of the monument in the urban structure and the experiences of the minority, the history of the community and the Jewish community in the city. Due to the nature of the topic, the analysis was based on the research of archival materials, which is the basic method of work within the art history discipline. In addition to the study of the inventory materials and the object itself, the content of the article refers to the theses of the most important researchers of synagogue architecture and town planning in Poland. An important context of the work were ethnographic and memory-related themes, which are an attempt to present the topic of synagogue architecture in a wider, social context. The greatest value of the paper is the original, so far unprecedented attempt to implement an interdisciplinary perspective in the analysis of synagogues. Moreover, the article deals with the subject of the New Synagogue in Czestochowa, which has not been subject to any systematic study so far. This article was written as part of over six years of research that I am conducting on this subject (research mainly in the context of the architecture of the New Synagogue in Czestochowa).
SÍSIFA SORDA: UNA APROXIMACIÓN A LA SITUACIÓN DE LAS MUJERES SORDAS EN COLOMBIA
Authors: Edith P. Rodríguez Díaz
Published: September 2024

Los problemas de las mujeres sordas en Colombia han tenido poca difusión y, por consiguiente, escasea la discusión e  investigación en el tema. Y en caso de discutirse, se aprecia una baja representatividad de ellas en espacios académicos y  políticos para incidir positivamente a su favor como minoría lingüística. Este ensayo recoge algunos hechos y experiencias para abrir el camino a la reflexión y así aportar una interpretación sobre la magnitud de los retos de la diversidad femenina sorda, bajo la figura de un Sísifo femenino como imagen representativa de la magnitud del problema, que enfrenta en cuanto a la discriminación y la violencia en Colombia.
SER E ESTAR DA MULHER INDÍGENA SURDA
Authors: Vilhalva Shirley
Published: September 2024

Esse artigo tem como objetivo apresentar a escrita que nasce do cotidiano de uma mulher indígena surda,  professora, pesquisadora e participante dos Movimentos Surdos Brasileiros, focalizando a potencialidade do Ser e Estar da mulher indígena surda na sociedade brasileira, bem como os direitos linguísticos e seu  espaço cultural enquanto escritora e poetisa, seja em língua de sinais, línguas indígenas de sinais, ou em português. São analisados os direitos para formação cultural da identidade de famílias bilíngues de indígenas e não indígenas surdos. A metodologia deste artigo é “Escrevivência” que, segundo Evaristo (2007), é uma produção narrativa que valoriza as experiências pessoais. Como resultado, destaca-se que, apesar  das legislações e demais conquistas alcançadas depois dos anos 1980, há a necessidade de novas propostas, principalmente quanto aos diversos direitos linguísticos das comunidades surdas e especificidades em relação aos direitos humanos, assim como novas pesquisas voltadas ao campo de estudos sobre as mulheres indígenas surdas do Brasil, suas línguas de sinais (LIS) e suas culturas étnicas.
O DIREITO INTERNACIONAL E A PESQUISA CIENTÍFICA MARINHA
Authors: Fiorati Jete Jane
Published: September 2024

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A comparative analysis of factors determining the value of the Indonesian Sharia Stock Index (ISSI) before and after the Covid-19
Authors: Franadita Dwi , Daulay Aqwa Naser , Dharma Budi
Published: September 2024

IntroductionThe Covid-19 pandemic had profound impacts on global financial markets, prompting extensive research to understand how various economic sectors, including sharia-compliant stocks, responded to the crisis. ObjectivesThis study aims to compare the determinant factors affecting the ISS (Indonesian Sharia Stock Index) during the periods before and after Covid-19 in Indonesia.MethodA descriptive and verificative quantitative research method was employed, validating collected data and examining the relationships between variables using statistical procedures to test research hypotheses. The data sources utilized were secondary data published by the Indonesia Stock Exchange (IDX). Data analysis techniques included Normality Tests and Paired Sample T-tests. Data processing was assisted by SPSS for Windows Version 22.00. The sample comprised data from the Indonesian Sharia Stock Index before and after Covid-19, covering the period from 2018 to 2022.ResultsThe study's findings indicate an increase in the Indonesian Sharia Stock Index post-Covid-19, with a significant difference observed before and after Covid-19.ImplicationsThe significant increase in the Indonesian Sharia Stock Index post-Covid-19 implies that sharia-compliant investments demonstrated resilience and potential for recovery in the face of economic disruptions, highlighting their viability as a robust investment option during and after financial crises.Originality/NoveltyThis study provides a novel comparative analysis of the factors influencing the Indonesian Sharia Stock Index before and after Covid-19, offering new insights into the pandemic's differential impact on sharia-compliant financial instruments.
Who Let the Dog and Cat Out? The Emergence of Stray Animal Care Non-Governmental Organisations in Brunei Darussalam
Authors: Alikhan Nurul Farhanah , Alam Meredian
Published: September 2024

Until today, the existence of stray animals remains a source of contention between the public and the authorities. Public policy seems to be elusive in regulating this phenomenon, as it presents sociocultural conundrums. While there is a continued unclarity in the government regulations, cultures, and normative values; non-government organisations emerged with autonomous resources to take care of stray animals. The present study examines the efforts of several Non-Governmental Organisations (NGOs) in Brunei that are committed to the rescue and treatment of stray animals via the rising phenomenon of stray animals. Despite receiving no financial support from the Government, these stray animal care organisations consistently forge informal co-operative networks with members of the public and non-governmental organisations; in order to sustain their resources, maintain daily operations, and manage finances and other stray animal-related health issues.
Application of Machine Learning to Understand PFAS Occurrence, Distribution, Transport and Removal in Water
Authors: Ajao Adewale , Almousa Mousa
Published: September 2024

Per- and polyfluoroalkyl substances (PFAS) are arguably the most common water contaminants in the world today. While several research experiments have been done to understand and remove PFAS from the environment, there is still a lot of unknown. Little has been known about the use of Machine learning (ML) to understand PFAS. This work hence reviews some leading ML approaches and applications in PFAS studies in the distribution, transport, removal, and occurrence predictions of PFAS. Several evaluation matrices were examined and used to perform this function. There are still a lot of areas whereby ML can be used to improve our PFAS knowledge base, some of these were briefly stated in this review.
The Influence of Perceived Overqualification on Constructive Deviant Behavior: The Moderating Role of Digital Leadership Across Generations
Authors: Meng Xiulan , Yu Xiaohua , Meng Xiulan
Published: September 2024

This study, based on proactive motivation theory, explores the relationship between perceived overqualification, digital leadership, and constructive deviant behavior, as well as generational differences. Using data collected in two waves from 596 employees, the results show that perceived overqualification positively influences constructive deviant behavior, and digital leadership enhances this effect. Employees born in the 1980s are most influenced by both factors, followed by those born in the 1990s, where the effect of digital leadership is less significant. The study suggests that effectively utilizing digital leadership and recognizing generational differences in perceived overqualification can help organizations better manage overqualified talent, improving employee satisfaction and productivity.
Combination Therapy for Multi-Drug-Resistant Mycoplasma genitalium
Authors: Kenyon Chris
Published: September 2024

In Belgium, around a quarter of M. genitalium infections are resistant to both macrolides and fluoroquinolones -termed multi-drug-resistant (MDR) infections. It is unclear what the best treatment is for these infections. We report the first two cases of MDR M. genitalium urethritis treated with combination therapy of minocycline, metronidazole, methenamine and pristinamycin. In both cases, this treatment resulted in microbiological and clinical cure.
Exploring Silica Nanoparticles: A Sustainable Solution for Pest Control in Sri Lankan Rice Farming
Authors: Wang Zeyu , Thavarajah Nirusha , Fernando Xavier
Published: September 2024

Rice cultivation stands as a cornerstone of Sri Lanka's economy, serving as a vital source of em-ployment for rural communities. However, the constraints of limited land availability have prompted an escalating dependence on agrochemicals, notably for pest management, thereby posing significant threats to human health and the environment. This review delves into the ex-ploration of silica nanoparticles as a promising eco-friendly substitute for conventional pesticides in the context of Sri Lankan rice farming. It comprehensively examines various aspects including the synthesis methods of silica nanoparticles, their encapsulation with synthetic pesticides, and an evaluation of their efficacy in pest control. Furthermore, it sheds light on the innovative utilization of agricultural waste such as rice husk and straw in the production of silica-based nano-pesticides. This approach not only demonstrates a shift towards sustainable agricultural practices but also aligns with the principles of green chemistry and circular economy, offering a holistic solution to the challenges faced by the rice farming sector in Sri Lanka.
Sputum Induction in Pediatric Lung Disease: Are We There Yet?
Authors: Kockar Kizilirmak Tuba , Bruscia Emanuela M , Britto Clemente J , Egan Marie E
Published: September 2024

Sputum induction (SI) is a non-invasive technique to obtain lower airway samples from people who do not spontaneously produce sputum. Since its introduction in 1958, its use has significantly increased for various respiratory conditions, especially with the establishment of standardized techniques. It has been used in pediatric research since 2002, starting with asthma studies. It is a safe and repeatable procedure for non-expectorating children. The ability to analyze both cellular and fluid components of sputum provides valuable information about lung diseases. This work reviews the utility of sputum induction in pediatric respiratory research and its potential clinical applications. We also discuss the safety, tolerability, and side effects profile of the procedure, emphasizing its significance in pediatric respiratory research. Despite the valuable insights gained from SI studies, challenges remain for widespread clinical utilization, requiring further refinement of the technique and increased accessibility in clinical settings.
GPU Acceleration Techniques for Analyzing the Photochemical Properties of Nanoparticles in Bioinformatics Frameworks
Authors: Okunola Abiodun
Published: September 2024

The integration of nanoparticles in biomedical applications requires precise analysis of their photochemical properties. However, computational simulations of these properties are computationally intensive, hindering rapid advancement. This study explores the implementation of Graphics Processing Unit (GPU) acceleration techniques to enhance computational efficiency in analyzing nanoparticle photochemistry within bioinformatics frameworks.By leveraging GPU parallel processing capabilities, we developed optimized algorithms for photochemical property simulations, achieving significant speedup over traditional Central Processing Unit (CPU)-based methods. Our GPU-accelerated framework demonstrated substantial performance gains in computing photochemical properties, such as absorption spectra and energy transfer rates.
Influence of Al and Ti Alloying and Annealing on the Microstructure and Compressive Properties of Cr-Fe-Ni Medium-Entropy Alloy
Authors: An Keyan , Yang Tailin , Feng Junjie , Deng Honglian , Zhang Xiang , Zhao Zeyu , Meng Qingkun , Qi Jiqiu , Wei FuXiang , Sui Yanwei
Published: September 2024

This research investigates the impact of Al and Ti elements on the formation of self-generated ordered phase in high-entropy alloys (HEA), which have been receiving widespread concentration in present times thanks to their remarkable multifunctional properties and wide range of component selection. By adjusting the dual elements of Al and Ti, the study explores the regulation of quantity and distribution of the in-situ self-generated ordered phases in the alloy. The results of the annealing heat treatment process demonstrated that, through accession Al and Ti elements, the Cr-Fe-Ni medium-entropy alloy transfer from BCC phase to BCC+FCC phase and the precipitation of new phases such as B2, L21, and σ. This led to a synergistic impact of second phase strengthening, and also of solid solution strengthening, resulting in improved compressive properties of HEA.
Harnessing AI in Information Technology to Optimize Nanoparticle Synthesis via Photochemical Methods
Authors: Okunola Abiodun
Published: September 2024

This study explores the synergistic integration of Artificial Intelligence (AI) in information technology with photochemical methods to optimize nanoparticle synthesis. By leveraging machine learning algorithms and predictive modeling, we demonstrate significant enhancements in the precision, efficiency, and scalability of nanoparticle production. AI-driven analysis of reaction parameters, optical properties, and structural characteristics enables real-time monitoring and adaptive optimization of photochemical reactions.The developed framework utilizes deep learning techniques to correlate reaction conditions with nanoparticle size, shape, and composition, facilitating the synthesis of tailored nanoparticles for various applications. Results show improved monodispersity, increased yield, and reduced synthesis time compared to traditional methods.This innovative approach paves the way for the rapid development of high-performance nanoparticles in fields such as biomedical imaging, energy storage, and catalysis. By harnessing the power of AI in information technology, this research unlocks new possibilities for the precise and efficient synthesis of nanoparticles via photochemical methods.
Self-control Buffers the Mortality Salience Effect on Fairness-related Decision-making
Authors: Li Wen , Guan Lili
Published: September 2024

Fairness-related decision-making often involves a conflict between egoistic and prosocial motives. Previous research based on Terror Management Theory (TMT) indicates that mortality salience can promote both selfish and prosocial behaviors, leaving its effect on fairness-related decision-making uncertain. By integrating TMT with the strength model of self-control, we propose that managing death-related thoughts depletes self-control strength, thereby impairing individuals' ability to resist selfish impulses during fairness-related decision-making tasks. Additionally, this effect is moderated by dispositional self-control. We tested these hypotheses in two studies. Participants were primed with either mortality salience or negative affect and then asked to made a series of binary choices (equal allocation vs. unequal allocation favoring themselves) to distribute monetary resources. In both studies, mortality salience heightened selfish tendencies, leading allocate resources less equitably. Study 2 further revealed that this effect occurred among participants with low, but not high, self-control. These findings indicate that mortality salience promotes selfishness and inequitable resource allocation, but that self-control can buffer these effects.
Class Incremental Learning for Financial Data Streams and Two Classes of Methodologies
Authors: Milner Larry
Published: September 2024

Class Incremental Learning (CIL) has emerged as a vital machine learning paradigm, particularly suited for environments with continuous data streams, such as those encountered in the financial industry. CIL enables models to progressively acquire and accumulate new knowledge without retraining the entire dataset, making it highly efficient for dynamic financial markets. In this paper, we explore the application of CIL to financial data streams, where high-frequency, high-dimensional data, such as stock prices and cryptocurrency transactions, evolve rapidly. The challenges inherent in CIL, including catastrophic forgetting—where the model loses previously learned knowledge—and intransigence—where it resists learning new classes—are addressed through both regularization-based techniques and dynamic architecture expansion. We present a comprehensive analysis of the algorithms designed to mitigate these challenges and highlight their relevance in financial applications like algorithmic trading, portfolio management, risk assessment, and fraud detection. By demonstrating how CIL enables models to adapt to new market conditions and asset classes while retaining past knowledge, we illustrate its critical role in advancing real-time financial decision-making. Through a detailed examination of the methodologies and their applications, this paper aims to provide insights into the future of adaptive financial models using Class Incremental Learning. We have also summarized methodologies into a model optimization-based class and a data focused class.
Presenting a Model for School Dropout of Girls in Deprived Areas Based on a Qualitative Investigation: A Case Study
Authors: Mashayekhi Sara , Mohammadi Parsa
Published: September 2024

Education plays a key role in human societies and the development of nations. Providing social justice in a country creates educational justice, and educational justice grants equal opportunities for growth and prosperity to the members of the society. In reality, there are differences between urban and rural educational facilities, as well as between girls and boys. Deprived and rural areas are full of losses, from economic problems to intellectual and cultural blockages. Failure to enhance these areas leads to further decline in these environments, and one of its consequences in education is the dropout of students. Girls are especially exposed to this problem due to gender discrimination, traditional and religious views, and living conditions. The purpose of this research was to obtain in-depth information about the experiences and reactions of girls in deprived areas and to identify its factors. This case study was conducted in the Khuzestan province of Iran using the grounded theory, and the results of the interviews were categorized after coding and its paradigm model was presented. In the end, solutions were presented to reduce the dropout rate of girls in deprived areas and prevent this problem.
Novel Acid-Assisted Polymerization Technique for Synthesis of Polyaniline Films at Room Temperature: Morphological Study and Supercapacitor Applications
Authors: Boahene Stephen , Potocký Štěpán , Dragounová Kateřina Aubrechtová , Tomšík Elena , Kromka Alexander
Published: September 2024

This study presents polyaniline (PANI) synthesis and characterization using a novel acid-assisted polymerization technique. Two PANI suspensions with different ammonium peroxydisulfate (APS) concentrations were synthesized at room temperature, i.e. the ratio of aniline to APS was 10:1 for PANI1 and 5:1 for PANI2. SEM measurements revealed distinct structures: a porous nanofibrillar structure for PANI1 and a densely packed structure for PANI2. The electrochemical performance of the fabricated PANI/glassy carbon (GC) electrodes was evaluated using a three-electrode cell configuration in the scan rates of 10 mV/s and 30 mV/s. The PANI1/GC heterostructure exhibited a specific capacitance of 160 F/g, while this value increased to 407 for the PANI2/GC. This research contributes not only to the understanding of PANI synthesis at room temperature but also to its potential applications in electrochemical energy storage devices.
Synthetic Biology Approaches for Engineering of Secondary Metabolism in Streptomyces: Manipulation of Crosstalk between Primary and Secondary Metabolism
Authors: Krysenko Sergii
Published: September 2024

Organisms from the genus Streptomyces feature actinobacteria with complex developmental cycle and great ability to produce a variety of natural products, which is possible due to complicated crosstalk between primary and secondary metabolism. These soil bacteria produce more than 2/3 of antibiotics used in medicine, and a large variety of bioactive compounds for industry and agricultural use. Although Streptomyces spp. have been studied for decades, the engineering of these bacteria remains challenging, and available genetic tools rather limited. Recent advancements in genetic manipulation of Streptomyces involving proposal of CRISPR/Cas9-based workflows as well as synthetic components (e.g. promoters, ribosome-binding sites, terminators, reporter genes) allowed to facilitate the turnaround time of strain engineering, but still has strain-specific limitations. However, a new perspective offered by synthetic biology to exploit the potential of existing and novel pathways in primary and secondary metabolism allows combining of different biosynthetic steps originating from diverse bacteria using a limited toolbox. Manipulation of interplay between primary and secondary metabolism proposes strategies to overcome strain-specific difficulties in engineering, leveraging insights in Streptomyces-specific physiological features. In this review, developments of these approaches for Streptomyces engineering are discussed and an overview of the synthetic biology developments is provided.
On the Protocols of New Historicism and Epochal Thought: A proposition
Authors: Penzance Isaac
Published: September 2024

The modern Historicism is plagued by its non-scientific appropriation – rightfully so, if we consider the genocidal proclivities that have defined the post-modern era to act on a perceived justification for the historical process, then the philosophy is little more than a falsely asserted and criminal interpretation made by taxonomists and romanticists. Yet, it should be noted that the study retains significant value in the discussion of Epochs, but its pertinence is represented in degrees of unknowable ideas and uncertainties. This article introduces two new, pragmatic constituent studies of Historicism such that it is reformed in the context of indeterminacy and an expected, non-processional characterization becomes forefront to the study.
Linguistic Cultures in Tandem to International Business Expansion
Authors: Seo Eugene
Published: September 2024

Cultural differences between nations lessens the degree of commerce and interactions that are performed. This could cause degredation in economic shifts, which could alter and devestate the lives of many people.
Applying the Multifractal Model of Asset Returns (MMAR) to Financial Markets: Insights and Limitations
Authors: Gottimukkala Srinivas Raju
Published: September 2024

This study presents an application of fractal mathematics to financial markets through the utilization of the Multifractal Model of Asset Returns (MMAR). The model is employed to analyse a 30-year dataset encompassing three distinct financial markets: the USD/NOK currency pair, the OMXS30 stock index, and the 12-month LIBOR rate. The MMAR model successfully captures essential stylized facts about financial markets, including high kurtosis, non-independent price movements, and clustered volatile days. Simulations generated by the model demonstrate realistic behaviour and multifractal characteristics. However, the model lacks a statistical method for assessing its accuracy and may underestimate kurtosis in high-kurtosis markets. Notably, the model is capable of producing simulations across a wide range of kurtosis values and can be instrumental in stress-testing portfolios. Despite its potential, the model is subject to limitations, such as the need for human judgment, ambiguous predictions, and interpretability issues. Furthermore, the model may become unreliable following a high-kurtosis event.
Modeling and Simulation of a Hydro Generator Stator Bar
Authors: Cheng Yujia , Yu Guang
Published: September 2024

As motor capacity and rated voltage increase, the demand for motor insulation also increases. Additionally, the electric field distribution at the end of a large-scale hydro generator is extremely non-uniform, and corona discharge readily occurs. This destroys the main insulation, which significantly affects the service life of electrical machinery. Thus, the regulation of the electric field concentration at the end of a large-scale hydro generator needs to be addressed. There are many problems in resistance–capacitance chain model research. Particularly, these models cannot accurately reflect the insulation, corona structure, and electric field distribution in electrical machinery. Additionally, the corner electric field and loss distributions cannot be obtained, leading to a higher calculation error. The electric field distribution at the motor end and the loss distribution were analyzed using the finite-element method. First, by applying the basic principles of electric circuits and electromagnetic field theory, we calculated the electric field distribution at the stator bar end. Second, a 3D model of the stator bar was built using Creo Parametric, yielding a model that is more closely related to the prototype wirebar model. Then, the potential, electric field, and loss distributions around the stator bar were simulated by using COMSOL simulation software. The effects of the circular arc corner, nonlinearity coefficient, anti-corona coating length, and resistivity of the stator bar on the electric field distribution at the motor end were explored.
Limited Local Clinical Trials for the New Cancer Treatment Technology Karanahan for Patients with Advanced Breast Cancer
Authors: Markina Veronika A , Proskurina Anastasia S , Ruzanova Vera S , Ritter Genrikh S , Dolgova Evgeniya V , Kirikovich Svetlana S , Levites Evgeniy V , Oshihmina Sofya G , Efremov Yaroslav R , Vereschagin Eugene I , Leplina Olga Y , Ostanin Alexandr A , Chernykh Elena R , Kolchanov Nikolay A , Sidorov Sergey V , Bogachev Sergey S
Published: September 2024

(1) Background: Multi-year research into the synergistic effect of cyclophosphamide and complex composite double-stranded DNA preparation (DNAmix) has made it possible to develop the novel Karanahan technology for treating malignant tumors, which is based on the eradication of cancer stem cells; (2) Methods: Pilot clinical trials for Karanahan technology were conducted in 12 patients with advanced stage IV breast cancer; (3) Results: The findings indicate that the analyzed treatment regimen ensures a local positive therapeutic response, significantly increases patient survival time, and activates the adaptive antitumor immune response. Adjustment of the basic regimen of Karanahan technology has been developed, which consists of increasing the dose of the DNAmix complex composite double stranded DNA preparation and its lymphotropic administration to the main lymph depots simultaneously with intratumoral injection; (4) Conclusions: Karanahan technology has a promising therapeutic potential in the treatment of inoperable stage IV breast cancer.
Therapeutic Applications of Botulinum Neurotoxin: Insights from a Comprehensive Literature Review
Authors: Mehta Rahul , Nagar Charulatha
Published: September 2024

Botulinum toxin (BoNT) is recognized as one of the most potent neurotoxins, with a lethal dose as low as 2 ng/kg, but it has also demonstrated significant therapeutic potential in controlled doses. Produced by the gram-positive anaerobic bacterium Clostridium botulinum, BoNT exists in eight distinct serotypes (A, B, C1, C2, D, E, F, and G) that disrupt neuronal transmission by targeting the soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNARE) complex at the neuromuscular junction, inhibiting the release of acetylcholine and inducing flaccid paralysis. While BoNT is notorious for its toxicity, it has been repurposed for medical use across various clinical indications. Following their approval by the Food and Drug Administration (FDA), these toxins have been associated with significant improvements in patient outcomes, particularly for individuals with specific neuromuscular disorders such as spasticity, dystonia, and cerebral palsy, as well as non-neuromuscular conditions like hyperhidrosis and cosmetic concerns. This broad spectrum of therapeutic applications that botulinum neurotoxins offer has made them an integral part of contemporary healthcare. Considering their growing importance, a detailed evaluation of their pharmacological properties, available formulations, and clinical uses is crucial. This review provides a comprehensive analysis of BoNT's molecular structure, mechanism of action, and therapeutic applications, with a particular emphasis on the most widely used BoNT-A formulations: OnabotulinumtoxinA (Botox), AbobotulinumtoxinA (Dysport), and IncobotulinumtoxinA (Xeomin). We examine their clinical efficacy, safety profiles, and differences in pharmacological properties to guide healthcare providers in selecting the most appropriate treatment for various conditions. Additionally, the review explores the challenges of BoNT therapy, such as immunogenicity and dosing considerations, while highlighting its evolving role in neurorehabilitation and conservative treatment strategies.
Study on the Influences of Idler Materials on Rolling Electrical Contact Performance
Authors: Wu Haihong , Qian Zhiyuan , Qu Chuankun , Zhang Lei , Liu Huiqun , Kang Xiao
Published: September 2024

The parallel connection of multiple flexible rings in raceways can significantly improve the electrical conductivity of rolling conductive devices. Multiple flexible rings are generally separated by idlers to form ring-idler rolling pairs. In the present work, alumina (Al2O3), polytetrafluoroethylene (PTFE), polyether ether ketone (PEEK), and polyimide (PI) were used as idler materials. Rolling tests for four types of ring-idler contact pairs were carried out in the air at a rotating speed of 10 rpm and a current of 60 A. It was noticed that the voltage drop was the lowest when Al2O3 was incorporated as the idler material. The energy spectrum analysis indicated material transfer between the organic idlers and the flexible ring. Especially on the flexible ring surface, the transferred organic thin film covered the gold-plated layer of the flexible ring and affected the electrical contact of the flexible ring. The transfer of Al2O3 was not obvious, and the mass fraction of Au on the flexible ring surface after the rolling test was 93.1%. The above results could help in selecting the best idler material for high-power conductive rotary joints.
On Atomic Elasticity
Authors: Connerade Jean-Patrick
Published: September 2024

It is argued that the compressibility of individual atoms is distinct from the compressibility of matter as a whole. The latter arises from variations in interatomic spacing, whereas the former is a purely quantum effect, characteristic of a given atomic species. Its magnitude can be deduced by solving the Schrödinger equation for an individual many-electron atom with modified external boundary conditions. Over a wide range of parameter space, quantum dilation or compression remains isoelectronic for neutral atoms but, at ultra-high pressures, reordering of their shell structure can occur. Their compression then ceases to be isoelectronic and their chemical properties, as well as their positioning in the Periodic Table, undergo sudden change.
An Ensemble Approach to Stock Price Prediction Using Deep Learning and Time Series Models
Authors: Sui Mujie , Zhang Cheng , Zhou Li , Liao Shuhan , Wei Changsong
Published: September 2024

The prediction of stock prices is a challenging task, particularly for retail investors who may lack the resources and expertise to perform sophisticated quantitative trading. This study focuses on enhancing stock price prediction for retail investors by employing advanced machine learning techniques on data from the stock exchange market. We utilize a comprehensive methodology that includes data preprocessing to handle missing values and outliers, feature engineering, cross-validation, and parameter tuning. The techniques applied include Keras Deep Neural Networks (DNN), LightGBM, LSTM, GRU, and linear regression (LR). Our proposed ensemble model, which combines time series and deep learning models, demonstrates superior performance compared to individual models. This integration of methods leads to significant improvements in prediction accuracy, providing a robust solution for retail investors.
The Other Effective Area-Based Conservation Measures Research on Key Considerations and Policies in Taiwan
Authors: Shih Yi-Che
Published: September 2024

The study provides a comprehensive and detailed analysis of the existing key policies and considerations in Taiwan's Other Effective Area-Based Conservation Measures (OECMs), with the objective of providing useful evidence-based insights for formulating new effective environmental-friendly policies and promoting the existing policies. The study adopts a mixed research methodology that entails the combination of qualitative and quantitative research methodological frameworks. The primary source of the quantitative data for the study is the World Database on Protected Areas (WDPA) which provides variable data on OECMs and a component of databases of the Protected Planet Initiative (PPI) which is the joint product of UNEP and IUCN, managed by UNEP-WCMC and the IUCN working with governments, communities and collaborating partners. The qualitative methodological framework for the research adopted a technical systematic review approach based on the three-step framework for systematic reviews that involved planning, conducting and reporting the review. The review was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The sources that were included in the review included scientific research materials that focused on the policies related to OECMs. Taiwan has a total of 92 individual areas that are designated as national protected areas (PAs) and OECMs and formally recognized by the World Database on Protected Areas (WDPA). Out of the 92 designated areas, only seven are managed by the Construction and Planning Agency while the remaining 85 areas are managed by the Forestry Bureau. In terms of designation, 37 areas are designated as major wildlife habitats, 21 areas are designated as nature reserves, 20 areas are designated as wildlife refuges, eight areas are designated as national parks and six areas are designated as forest reserves. The primary themes that were identified were associated with marine spatial planning, environmental impact assessment (EIA) and marine scientific research and included biodiversity, protected area consideration, geographically defined areas, coastal resources and marine ecosystems. Other Effective Area-Based Conservation Measures (OECMs) have not been widely implemented yet, but most countries, including Taiwan, are increasingly aligning their existing policies with the strategies outlined in the OECMs policies to achieve large area-based conservation targets and reduce biodiversity loss.
A Conceptual Framework for Costing Perovskite Solar Cells through Material Flow Cost Accounting
Authors: van der Poll Hendrik Johannes , van der Poll Huibrecht Margaretha , van der Poll John Andrew
Published: September 2024

There is a global demand for alternative energy sources away from unsustainable fossil fuels. COP26 agreed that fossil fuels should be phased down; at COP27, anxiety about the cost and availability of energy was raised, and COP28 reiterated the phasedown of coal power. Solar technology in the form of Perovskite solar cells is one such alternative energy source. This article considers the fabrication of the Perovskite layer in a solar cell and postulates the extent to which Material Flow Cost Accounting (MFCA) could be used as a feasible costing method, among other things, to address byproduct and waste generation. Through MFCA, the monetary and physical flows of materials are identified and can be applied throughout the supply chain to facilitate affordability, from the extraction of the ore, transportation, fabrication of the chemicals, manufacturing and distribution of the solar cell and panels, and finally, the recycling of the panel. Informed by these observations, a conceptual framework for applying MFCA in fabricating the Perovskite layer in the supply chain is developed based on sets of qualitative propositions. Future work will be researching the processes of manufacturing solar cells, costing raw materials, energy flows, and solar cell manufacturing emissions.
KAJIAN INDIKATOR ASAS PROPORSIONALITAS DALAM DRIVER CONTRACT ANTARA PT GOJEK INDONESIA DAN MITRA DRIVER
Authors: Az Zahra Shofwatul Islamia , Kharisma Dona Budi
Published: September 2024

This article is to examine the indicator principle of proportionality of an electronic contract between PT Gojek Indonesia and Driver Partners. This articel is normative legal research conducted with an evaluative approach. The type of data used is secondary data which includes primary and secondary legal materials. The result shows that the characteristics of an electronic contracts based on the principle of proportionality have three aspects, namely the equal rights and obligations, the liberty in establishing the substance of the agreement, and the guarantee of rights’ implementation as well as the distribution of obligations proportionally. The identification of electronic contracts between PT Gojek Indonesia and Driver Partners resulted in the absence of the utilization of the proportionality principle. To even the rights and obligations of the parties involved, an ideal solution proposed is the enforcement of the proportionality principle in standart electronic contracts.
PERLINDUNGAN HUKUM TERHADAP KREDITUR DALAM PERJANJIAN KREDIT DENGAN CASH COLLATERAL KETIKA DEBITUR WANPRESTASI
Authors: Jinan Nurul , Pranoto '
Published: September 2024

Artikel ini bertujuan untuk mengkaji perlindungan hukum terhadap kreditur dalam perjanjian kredit dengan cash collateral ketika debitur wanprestasi di PT Bank Rakyat Indonesia (BRI) Cabang Tangerang. Penelitian hukum ini merupakan penelitian hukum empiris, jenis dan sumber data data yang digunakan adalah data primer berupa hasil wawancara serta data sekunder yang berupa bahan hukum primer yaitu ketentuan undang-undang dan bahan hukum sekunder yaitu buku, jurnal, bahan-bahan kepustakaan yang berkaitan dengan penelitian ini. Sifat penelitian yang digunakan adalah penelitian deskriptif analitis dengan menggunakan pendekatan kualitatif. Hasil penelitian menunjukkan bahwa dalam pengikatan perjanjian kredit yang dilakukan oleh kreditur dan debitur, terdapat didalamnya suatu klausul mengenai objek jaminan yang diberikan debitur sebagai bentuk dari kesanggupannya untuk melunasi utang seperti cash collateral yang dapat berupa rekening tabungan, bilyet deposito, maupun giro. Perlindungan hukum bagi kreditur dalam hal memberikan fasilitas kredit dengan cash collateral jika debitur wanprestasi terletak pada adanya surat kuasa yang diberikan debitur kepada kreditur untuk mencairkan isi dari cash collateral tersebut sebagai pemenuhan utangnya.
DAMPAK PERATURAN MENTERI ESDM NOMOR 12 TAHUN 2020 TERHADAP INDUSTRI HULU MINYAK DAN GAS DI INDONESIA
Authors: Yeshinta Agnes , Imanullah Moch. Najib
Published: September 2024

Artikel ini bertujuan untuk mengkaji isu hukum yang menganalisa perbandingan skema Kontrak Bagi Hasil (PSC) Cost Recovery dan Gross Split dan dampak Peraturan Menteri ESDM Nomor 12 Tahun 2020 tentang Perubahan Ketiga Atas Peraturan Menteri ESDM Nomor 08 Tahun 2017 tentang Kontrak Bagi Hasil Gross Split terhadap Industri Hulu Migas di Indonesia. Kajian ini bertujuan untuk menemukan skema PSC yang dapat menguntungkan Negara dan KKKS serta untuk menemukan apa dampak yang telah dihasilkan oleh Peraturan Menteri ESDM Nomor 12 Tahun 2020 terhadap Industri Hulu Migas Indonesia. Untuk mencapai tujuan tersebut maka penulis melakukan penelitian yang menggunakan metode penelitian hukum normatif bersifat deskriptif. Sumber bahan hukum yang digunakan adalah bahan hukum primer dan bahan hukum sekunder, dengan cara studi pustaka/dokumen, teknik analisis bahan hukum menggunakan metode silogisme yang menggunakan pola pikir deduktif. Hasil penelitian menunjukkan bahwa skema Gross Split lebih menguntungkan bagi Negara maupun Kontraktor KKS serta Peraturan Menteri ESDM Nomor 12 Tahun 2020 yang dibentuk dengan tujuan untuk meningkatkan investasi Minyak dan Gas Bumi di Indonesia nyatanya belum menimbulkan dampak positif pada industri Migas Indonesia
KEDUDUKAN ISBAT NIKAH DALAM UNDANG-UNDANG NOMOR 1 TAHUN 1974 SEBAGAIMANA TELAH DIUBAH DENGAN UNDANG-UNDANG NOMOR 16 TAHUN 2019 TENTANG PERKAWINAN
Authors: Rahmatina Fauzia Ismu , Nugraheni Anjar Sri Ciptorukmi
Published: September 2024

Penelitian ini bertujuan untuk memahami dan menganalisis kedudukan isbat nikah dalam Undang-Undang Perkawinan serta akibat hukum yang timbul dari dikabulkannya maupun ditolaknya permohonan penetapan isbat nikah. Penelitian ini berjenis penelitian hukum normatif yang bersifat deskriptif dengan menggunakan pendekatan perundang-undangan. Penelitian ini bersumber dari bahan hukum primer dan bahan hukum sekunder. Teknik pengumpulan data berupa studi kepustakaan dengan teknik analisis bahan hukum berupa metode silogisme dengan pola pikir deduktif. Berdasarkan hasil penelitian dan pembahasan, terdapat kesimpulan yaitu kedudukan isbat nikah dalam Undang-Undang Perkawinan adalah sebagai mekanisme yang disediakan hukum bagi pihak-pihak yang ingin menunaikan Pasal 2 ayat (2) Undang-Undang Perkawinan atas perkawinan mereka yang belum dicatatkan, serta penetapan isbat nikah tersebut dapat dikabulkan maupun ditolak oleh para hakim dan keduanya menimbulkan akibat hukum yang berbeda. Akibat hukum yang timbul apabila dikabulkan antara lain, status perkawinan menjadi sah sesuai Pasal 2 ayat (1) dan ayat (2) Undang-Undang Perkawinan yang kemudian menimbulkan hak dan kewajiban antara suami dan istri, orang tua dan anak, serta hak waris mewaris. Apabila permohonan isbat nikah ditolak, maka hak dan kewajiban tersebut tidak ada menurut hukum negara.
Kata Kunci: Akibat Hukum; Isbat Nikah; Penetapan Perkawinan; Perkawinan.