bluuebunny/crossref_metadata_2025 huggingface dataset:
The Therapeutic Potential of Quercetin in Parkinson’s Disease: Insights into its Molecular and Cellular Regulation
Authors: Tamtaji Omid Reza , Hadinezhad Tooba , Fallah Maryam , Shahmirzadi Arash Rezaei , Taghizadeh Mohsen , Behnam Mohammad , Asemi Zatollah
Published: November 2019

Parkinson’s disease (PD) is a chronic and progressive neurodegenerative disorder characterized
by the progressive death of dopaminergic neurons in the substantia nigra pars compacta (SNc).
PD is a multifactorial disorder, with several different factors being suggested to play a synergistic
pathophysiological role, including oxidative stress, autophagy, underlying pro-inflammatory events
and neurotransmitters abnormalities. Overall, PD can be viewed as the product of a complex interaction
of environmental factors acting on a given genetic background. The importance of this subject has
gained more attention to discover novel therapies to prevent as well as treat PD. According to previous
research, drugs used to treat PD have indicated significant limitations. Therefore, the role of flavonoids
has been extensively studied in PD treatment. Quercetin, a plant flavonol from the flavonoid
group, has been considered as a supplemental therapy for PD. Quercetin has pharmacological functions
in PD by controlling different molecular pathways. Although few studies intended to evaluate
the basis for the use of quercetin in the context of PD have been conducted so far, at present, there is
very little evidence available addressing the underlying mechanisms of action. Various principal aspects
of these treatment procedures remain unknown. Here, currently existing knowledge supporting
the use of quercetin for the clinical management of PD has been reviewed.
The Use of Fibrin-based Tissue Adhesives for Breast in Reconstructive and Plastic Surgery
Authors: Chen Kuo , Sinelnikov Mikhail Y. , Nikolenko Vladimir N. , Reshetov Igor V. , Cao Yu , Li Zhi , Kochurova Ekaterina V. , Nikolenko Svetlana N. , Avila-Rodríguez Marco , Somasundaram Siva G. , Kirkland Cecil E. , Aliev Gjumrakch
Published: November 2019

Background:

Breast plastic surgery is a rapidly evolving field of medicine. The modern view of surgical trends reflects the desire to minimize complications and introduce advanced technologies. These always will be priorities for surgeons. Reconstructive surgery, a branch of plastic surgery focusing on restoration of lost functional and aesthetic component, seeks to enhance psychological rehabilitation and improves the quality of life, as well as aesthetic recovery.

Objective:

This review addresses the action of fibrin agents and their effect on the quality of surgical hemostasis.

Discussion and Conclusion:

The fundamental goals for the surgeon are to perform a minimally traumatic intervention and to prevent any form of complication. Achieving complete hemostasis is an intraoperative necessity. Timely prevention of bleeding and hemorrhagic phenomena can affect not only the outcome of the operation, but also the incidence of postoperative complications. Topics include the integrity of microvascular anastomoses, tissue adhesion, and the incidence of seromas and hematomas associated with fibrin glue usage. The literature on fibrin adhesives with respect to prevention of postoperative complications, and the effectiveness with active drainage also are analyzed.
Search for Potential Inducible Nitric Oxide Synthase Inhibitors with Favorable ADMET Profiles for the Therapy of Helicobacter pylori Infections
Authors: Rodrigues Ricardo Pereira , Ardisson Juliana Santa , Ribeiro Gonçalves Rita de Cássia , Oliveira Tiago Branquinho , Barreto da Silva Vinicius , Kawano Daniel Fábio , Kitagawa Rodrigo Rezende
Published: November 2019

Background:

Helicobacter pylori is a gram-negative bacterium related to chronic gastritis, peptic
ulcer and gastric carcinoma. During its infection process, promotes excessive inflammatory response, increasing
the release of reactive species and inducing the production of pro-inflammatory mediators. Inducible Nitric
Oxide Synthase (iNOS) plays a crucial role in the gastric carcinogenesis process and a key mediator of inflammation
and host defense systems, which is expressed in macrophages induced by inflammatory stimuli. In
chronic diseases such as Helicobacter pylori infections, the overproduction of NO due to the prolonged induction
of iNOS is of major concern.

Objective:

In this sense, the search for potential iNOS inhibitors is a valuable strategy in the overall process
of Helicobacter pylori pathogeny.

Method:

In silico techniques were applied in the search of interesting compounds against Inducible Nitric
Oxide Synthase enzyme in a chemical space of natural products and derivatives from the Analyticon Discovery
databases.

Results:

The five compounds with the best iNOS inhibition profile were selected for activity and toxicity predictions.
Compound 9 (CAS 88198-99-6) displayed significant potential for iNOS inhibition, forming hydrogen
bonds with residues from the active site and an ionic interaction with heme. This compound also displayed
good bioavailability and absence of toxicity/or from its probable metabolites.

Conclusion:

The top-ranked compounds from the virtual screening workflow show promising results regarding
the iNOS inhibition profile. The results evidenced the importance of the ionic bonding during docking selection,
playing a crucial role in binding and positioning during ligand-target selection for iNOS.
In Silico Drug-designing Studies on Sulforaphane Analogues: Pharmacophore Mapping, Molecular Docking and QSAR Modeling
Authors: Vaghefinezhad Neda , Farsani Samaneh Fazeli , Gharaghani Sajjad
Published: November 2019

Aims:

In the presented work we successfully discovered several novel NQO1 inducers using the computational approaches.

Background:

The phytochemical sulforaphane (SFN) is a potent inducer of carcinogen detoxication enzymes like NAD(P)H:quinone oxidoreductase 1 (NQO1) through the Kelch-like erythroid cellderived protein with CNC homology[ECH]-associated protein 1 (Keap1)–[NF-E2]-related factor 2 (Nrf2) signaling pathway.

Objective:

In this paper, we report the first QSAR and pharmacophore modeling study of sulforaphane analogues as NQO1 inducers. The pharmacophore model and understanding the relationships between the structures and activities of the known inducers will give useful information on the structural basis for NQO1 enzymatic activity and lead optimization for future rational design of new sulforaphane analogues as potent NQO1 inducers.

Methods:

In this study, a combination of QSAR modeling, pharmacophore generation, virtual screening and molecular docking was performed on a series of sulforaphane analogues as NQO1 inducers.

Results:

In deriving the QSAR model, the stepwise multiple linear regression established a reliable model with the training set (N: 43, R: 0.971, RMSE: 0.216) and test set (N: 14, R: 0.870, RMSE: 0.324, Q2: 0.80) molecules. The best ligand-based pharmacophore model comprised two hydrophobic (HY), one ring aromatic (RA) and three hydrogen bond acceptor (HBA) sites. The model was validated by a testing set and the decoys set, Güner–Henry (GH) scoring methods, etc. The enrichment of model was assessed by the sensitivity (0.92) and specificity (0.95). Moreover, the values of enrichment factor (EF) and the area under the receiver operating characteristics curve (AUC) were 12 and 0.94, respectively. This well-validated model was applied to screen two Asinex libraries for the novel NQO1 inducers. The hits were subsequently subjected to molecular docking after being filtering by Lipinski’s, MDDR-like, and Veber rules as well as evaluating their interaction with three major drugmetabolizing P450 enzymes, CYP2C9, CYP2D6 and CYP3A4. Ultimately, 12 hits filtered by molecular docking were subjected to validated QSAR model for calculating their inducer potencies and were introduced as potential NQO1 inducers for further investing action.

Conclusions:

Conclusively, the validated QSAR model was applied on the hits to calculate their inducer potencies and these 12 hits were introduced as potential NQO1 inducers for further investigations.
Enhancement Effect of Zn-Arsenazo III Complex for G-quadruplex DNA Stability of Proto-oncogene Promoter Telomeres
Authors: Zou Liyuan , Li Hongbo , Liu Mingbin , Zhao Weihua , Wang Suqin
Published: November 2019

Background:

Controlling the structure of proto-oncogene telomeres is very important in
antitumor therapy. There are relationships between G-quadruplex DNA and the growth of tumor cell.

Methods:

In this study, spectroscopic, cyclic voltammetry and viscosity methods were employed to
investigate the interaction between Zn-Arsenazo Ⅲ complex and G-quadruplex DNA by using 4S
Green Plus Nucleic Acid Stain as a spectral probe in PBS buffer. The binding ratios were n Arsenazo Ⅲ
: n Zn(Ⅱ) = 5:1 for Zn-Arsenazo Ⅲ complex and n Zn- Arsenazo Ⅲ : n G-quadruplex DNA = 8:1 for Zn-Arsenazo
Ⅲ-G-quadruplex DNA. The bonding constants (Kθ
298.15K=4.44x105 L·mol-1, Kθ
308.15K= 1.00x105
L·mol-1, Kθ
318.15K= 1.04x106 L·mol-1) were obtained by double reciprocal method at different temperatures, Which was found that the interaction between Zn-Arsenazo Ⅲ complex and Gquadruplex
DNA was driven by enthalpy. Furthermore, the research further confirmed that the interaction
mode between Zn-Arsenazo Ⅲ complex and G-quadruplex DNA was a mixed binding
which involved intercalation and non-intercalation interaction.

Results and Conclusion:

Together these findings also have corroborated the application of stabilizing
ligands and intervening with their function for target G-quadruplexes in a cellular context.
Improving Calcium Knowledge and Intake in Young Adults Via Social Media and Text Messages: Randomized Controlled Trial
Authors: Rouf Anika , Nour Monica , Allman-Farinelli Margaret
Published: November 2019

Background

Calcium is an important nutrient for the attainment of peak bone mass during adolescence and young adulthood. However, these life phases are characterized as hard to reach for health promotion. Social media platforms offer a promising channel as they are relatively low cost but used ubiquitously by youth.

Objective

The aim of the CAlcium Nutrition-Dietary Opportunities (CAN-DO) study was to conduct a randomized controlled trial to test the effectiveness of Facebook alone or with text messaging as channels to deliver a theory-based program to encourage optimal calcium intake.

Methods

The intervention was a 3-arm parallel trial. Young adults aged 18 to 25 years were recruited through university and social media for a 6-week trial. Participants were randomized to 1 of the 3 arms (ie, Facebook posts, Facebook posts plus text messages, and control group that received an electronic leaflet containing information on calcium intake). The primary outcome was change in intake of milk and other calcium-rich foods, and secondary outcomes were knowledge, self-efficacy, motivation, and habit formation concerning calcium-rich foods. Changes were assessed before and after the intervention, and the differences in change between groups were compared using multivariate regression models with multiple imputations for missing data.

Results

A total of 211 participants (64/211, 30.3% males) participated (mean age 21.4 years, SD 2.1) in this study. At the end of the program, no increase in milk intake (odds ratio [OR] 1.51, 95% CI 0.61-3.75 Facebook; OR 1.77, 95% CI 0.74-4.24 Facebook plus text messages; P=.41) nor calcium-rich food was detected (P=.57). There was a significant improvement in knowledge in the Facebook plus text messages group (P<.001), but habit formation improved less than that in the other 2 groups (P=.01). Our results showed a moderate level of engagement with intervention content and positive qualitative feedback from participants.

Conclusions

The CAN-DO study delivered via Facebook (with the additional support of text messages) was found to improve knowledge and was acceptable among young adults. However, further research is needed to better understand social media engagement and how to optimize the program for participants to be sufficiently motivated to increase their intake of calcium-rich foods.

Trial Registration

Australian New Zealand Clinical Trials Registry ACTRN12620000097943; http://www.anzctr.org.au/ACTRN12620000097943.aspx
Exploring the Vast Choice of Question Prompt Lists Available to Health Consumers via Google: Environmental Scan (Preprint)
Authors: Tracy Marguerite Clare , Shepherd Heather L , Patel Pinika , Trevena Lyndal Jane
Published: November 2019

BACKGROUND

There is increasing interest in shared decision making (SDM) in Australia. Question prompt lists (QPLs) support question asking by patients, a key part of SDM. QPLs have been studied in a variety of settings, and increasingly the internet provides a source of suggested questions for patients. Environmental scans have been shown to be useful in assessing the availability and quality of online SDM tools.

OBJECTIVE

This study aimed to assess the number and readability of QPLs available to users via Google.com.au.

METHODS

Our environmental scan used search terms derived from literature and reputable websites to search for QPLs available via Google.com.au. Following removal of duplicates from the 4000 URLs and 22 reputable sites, inclusion and exclusion criteria were applied to create a list of unique QPLs. A sample of 20 QPLs was further assessed for list length, proxy measures of quality such as a date of review, and evidence of doctor endorsement. Readability of the sample QPL instructions and QPLs themselves was assessed using Flesch Reading Ease and Flesch-Kincaid Grade Level scores.

RESULTS

Our environmental scan identified 173 unique QPLs available to users. Lists ranged in length from 1 question to >200 questions. Of our sample, 50% (10/20) had a listed date of creation or update, and 60% (12/20) had evidence of authorship or source. Flesch-Kincaid Grade Level scores for instructions were higher than for the QPLs (grades 10.3 and 7.7, respectively). There was over a 1 grade difference between QPLs from reputable sites compared with other sites (grades 4.2 and 5.4, respectively).

CONCLUSIONS

People seeking questions to ask their doctor using Google.com.au encounter a vast number of question lists that they can use to prepare for consultations with their doctors. Markers of the quality or usefulness of various types of online QPLs, either surrogate or direct, have not yet been established, which makes it difficult to assess the value of the abundance of lists. Doctor endorsement of question asking has previously been shown to be an important factor in the effectiveness of QPLs, but information regarding this is not readily available online. Whether these diverse QPLs are endorsed by medical practitioners warrants further investigation.
Analysis of Health Conditions Based on a National Health Information Trends Survey: Implications from Internet and Transport Access (Preprint)
Authors: Hu Qinglin , Li Xiaobing , Gregg Abbey
Published: November 2019

BACKGROUND

Internet access to health information & transportation to health care services are two very important ways to promote health and ameliorate health disparities. Despite the general widespread availability of transportation and Internet, disparities still exist among specific groups, particularly among traditionally undeserved (rural/remote) and minority populations. A better understanding of the spatial patterns of transportation and Internet access, along with their relationship to people’s general health status, may help improve our current health care system and programs.

OBJECTIVE

The purpose of this study was to explore the spatial distribution of people who have difficulties with transportation to health care and Internet access. We also examined the relationship between self-reported health status and transportation and Internet access barriers.

METHODS

We used data from the 2018 Health Information National Trends Survey (HINTS), a nationally representative sample of US households, to examine the association between transportation and Internet access with individual’s general health status. A geographic information map was generated to examine the geographic variation of both transportation to health care and Internet access barriers in the United States.

RESULTS

Individuals with limited transportation to health care and Internet access are associated with a lower level of health status, and Internet access seems to have a larger influence on general health status. Similarly, people who lived in a rural area were more likely to associate with fair or poor health status compared to those who lived in urban area. Respondents who were without health care insurance coverage were less likely to have an excellent or very good health status. Women tended to have better general health status then men, which is consistent with previous studies. In addition, people who had employment, higher education, higher income, and are of White race are more likely to have a higher level of general health status. Geographically, the East South Central and East North Central Divisions tended to have the lowest level of Internet and transportation access to health care, especially the states of Missouri, Tennessee, Mississippi and Alabama.

CONCLUSIONS

This analysis showed the mixed effects of transportation and Internet access on individual’s’ general health status. Both of the barriers are significant factors for people with health issues, and access disparities exist at the state level and between urban and non-urban areas. Additional work and policy is needed to ensure that Internet and transportation resources and services are prioritized for undeserved populations and areas.
Influence of Organizational Issues on Nurse Administrators’ Support to Staff Nurses’ Use of Smartphones for Work Purposes in the Philippines: Focus Group Study (Preprint)
Authors: Bautista John Robert , Lin Trisha T C , Theng Yin-Leng
Published: November 2019

BACKGROUND

Studies show that nurses use their own smartphones for work purposes, and there are several organizational issues related to this. However, it is unclear what these organizational issues are in the Philippines and the influence they have on nurse administrators’ (ie, superiors) support to staff nurses’ (ie, subordinates) use of smartphones for work purposes.

OBJECTIVE

Drawing from the Organizational Support Theory (OST), this study aimed to identify organizational issues that influence nurse administrators’ support to staff nurses’ use of smartphones for work purposes.

METHODS

Between June and July 2017, 9 focus groups with 43 nurse administrators (ie, head nurses, nurse supervisors, and nurse managers) were conducted in 9 tertiary-level general hospitals in Metro Manila, the Philippines. Drawing from OST, issues were classified as those that encouraged or inhibited nurse administrators to support nurses’ use of smartphones for work purposes.

RESULTS

Nurse administrators were encouraged to support nurses’ use of smartphones for work purposes when (1) personal smartphones are superior to workplace technologies, (2) personal smartphones resolve unit phone problems, and (3) policy is unrealistic to implement. Conversely, issues that inhibited nurse administrators to support nurses’ use of smartphones for work purposes include (1) smartphone use for nonwork purposes and (2) misinterpretation by patients.

CONCLUSIONS

Nurse administrators in the Philippines faced several organizational issues that encouraged or inhibited support to staff nurses’ use of smartphones for work purposes. Following OST, the extent of their support can influence staff nurses’ perceived organizational support on the use of smartphones for work purposes, Overall, the findings highlight the role and implication of organizational support in the context of smartphone consumerization in hospital settings, especially in developing countries.
Librarian role in research library services in Indonesian Institute of Sciences
Authors: Riyanto Slamet , Marlina Ekawati , Triasih Hermin
Published: November 2019

Introduction.In a research library, researchers are the main players, while . librarians should be the partners in conducting research even though this combination rarely happens. In general, librarians are only involved in a part of research activities as their research assistants to carry out some administrative stuffs, such as distributing questionnaires and sending invitation letters, instead of designing a research plan and/or somequestionnaires or doing data analyses.Data Collection Method. We interviewed librarians in the Center for Political Studies, Research Center for Economic, Center for Science and Technology Development, and Center for Scientific Documentation and Information of Indonesian Institute of Sciences, Jakarta.Data Analyses. Data were analyzed using qualitative analysis methods, through the direct interview, where data categorized by using open coding.Results and Discussions.The results stated that 86.7% of respondents had ever been involved in research activities carried out by the research center in the same or different units. From that result, 53.3% respondents ever engaged research activities up to 5 times in a year. In the other hands, librarians who answer conduct independent research and are often involved in the research are 13% respondents. Some recommendations figured out from this research are (1) a librarian could be a  plagiarism examiner for a research proposal, (2) a librarian must be literated in information technologies, (3) a librarian should be involved in examining a literature review of the proposal and writing the manuscripts.Conclusions.The role of a librarian is not just as a research assistant or a data collector but as a research buddy who could help addressing some documentative problems.
¿Cuál es la formación de la planta académica de la UNAM? El caso de los profesores de asignatura
Authors: Torres Carrasco Ruth
Published: November 2019

Este texto presenta una breve descripción estadística de una de las agrupaciones académicas más importantes de la UNAM, el profesorado de asignatura. Muestra de manera genérica cuál es su formación, edades y antigüedad de quienes desempeñan una de las funciones sustantivas de la Universidad: la docencia. La información que se expone toma como base los subsistemas universitarios donde se agrupa la mayor cantidad de profesores con esta figura académica: escuelas y facultades, entidades multidisciplinarias, la Escuela Nacional Preparatoria (ENP) y el Colegio de Ciencias y Humanidades (CCH).
Efecto de la inclusión de granos secos de destilería con solubles (DDGS) en la calidad de la canal y de la carne de conejos en crecimiento
Authors: Vázquez Pedroso Ysnagmy , Bernal Barragán Hugo , Valdivié Navarro Manuel Isidoro , Gutiérrez Ornelas Erasmo , Mora Castellanos Luis Marino , Sánchez Alejo Ernesto , Hernández Martínez Carlos Alberto
Published: November 2019

Se evaluó el efecto de la inclusión de diferentes niveles (0, 10, 20 y 30 %) de grano seco de destilería con solubles (DDGS), sobre la calidad de la canal y de la carne de conejos en crecimiento, utilizando 56 conejos (Negro Azteca x Chinchilla) de 40 días de edad. Terminado el período de ceba, se sacrificaron 20 conejos (5 por tratamiento) y se determinó la proporción de la canal conformada por las extremidades anteriores, extremidades posteriores, costillas y lomo. Se determinó el peso total de carne, hueso y grasa del lomo, y se calculó la relación carne:hueso para toda la canal. Se realizó la evaluación sensorial de la carne con 46 panelistas que valoraron el olor, color, sabor y textura. En el músculo Longissimus dorsi se determinó el color, evaluando la luminosidad (L*), el índice de rojo (a*) y el índice de amarillos (b*). Además, se evaluó textura mediante medición de la fuerza de ruptura. Los resultados de calidad de la canal y de la carne se analizaron por medio de ANOVA. Los resultados de la evaluación sensorial seevaluaron con estadística no paramétrica. No hubo diferencias (P>0.05) en las mediciones de la canal, características organolépticas ni textura de la carne. El parámetro b* del color de la carne fue mayor (P<0.05) en las dietas con 10, 20 y 30 % de DDGS (11.77, 12.17 y 12.22 respectivamente) comparado con la dieta control (9.68). La evaluación sensorial evidenció que la carne de conejo con o sin DDGS tuvo un olor y sabor agradable, color pálido y textura suave. Se concluyó que la inclusión de DDGS hasta 30 % en la dieta, no afectó las características de la canal ni de la carne de los conejos.
THE EFFECT OF LISTENING EDM GENRE TO STUDENTS’ PRONUNCIATION
Authors: Yuliadi Sigit , Pradana Sultan Arief , Yugafiati Rasi
Published: November 2019

Music dynamics is now infiltrated on the development of EDM (Electronic Dance Music) genre. Characteristics of those songs combine the beat, effects, and repetition of words. Those reasons make the EDM genre lovers dance. The genre is commonly found in bars, pubs, night clubs, performance and event venues (venues and appearances). This music genre is also found in radio and cable tv. Interestingly, the lyrics of the genre mostly use English. Although in this country, the lyrics sometimes are found in Bahasa. The lyrics in the EDM genre tend to be repetitive. Thus, the possibility of memorizing the lyrics in English may be higher. Memorize the lyrics in direct use when listening to the EDM genre, giving music lovers chance to produce acceptable pronunciation. The purpose of this study is to examine the mastery of English pronunciation through the lyrics of the EDM genre. The study involves three participants. This study uses descriptive qualitative method. The result of this research is that all participants feel helpful in improving English pronunciation ability by using EDM genre.
CODE MIXING IN ISLAMIC LECTURES BY USTADZ EVIE EFFENDI
Authors: Triana Asep , Eka Saputra Siddik Sembada
Published: November 2019

This study is aimed to find the kinds of code mixing and to know which kinds of code mixing are dominantly used in Islamic lectures by Ustadz Evie Effendi. Descriptive qualitative method is used in this study. The data were collected through watching, transferring, asking, playing, selecting and transcribing the data from the lectures. The collected data were then analyzed through identifying the data, selecting the data related to the code mixing, listing and classifying the data based on the kinds of code mixing and finally drawing conclusion. It was found that there are two kinds of code mixing used by Ustadz Evie Effendi, namely conversational and situational code mixing. Between two kinds of code mixing, conversational code mixing is dominantly used both by Ustadz Evie Effendi in which he sometimes change the pronunciation from English into Indonesian in the conversation.
THE CORRELATION BETWEEN ENGLISH GRAMMAR COMPETENCE AND SPEAKING FLUENCY
Authors: Kusumawardani Siska Anisa , Mardiyani Endah
Published: November 2019

The objective in this case to examine how English grammar competence can influence speaking fluency. The authorcharity quantitative method, and correlation research design. The population was 170 of tenth grade students from 6 classes, at MAN Cimahi in academic year 2018/2019 and the sample was 34 students from design class. The instruments took grammar test and speaking interview. The student’s grammar competence scores (X) and the student’s speaking fluency (Y) were analysed and it is found that the distribution of data is not normal. The result of data analysis showed that correlation coefficient (r) equals to 0.259, larger than social significance value which is 0.05. the interpretation of the relationship is weak correlation. The Null hypothesis is accepted.Keywords:Grammar Competence, Speaking Fluency
IMPROVING STUDENT WRITING ABILITY IN NARRATIVE TEXT THROUGH THINK TALK WRITE METHOD AT TENTH GRADE OF SMK PGRI 3 CIMAHI
Authors: Lisnawati Dina , Elvirasari Diana , Santoso Iman
Published: November 2019

The purpose of this research was to find out the improvement of students’ writing abilityin writing narrativetext through think talk write method.The design of this research is point out in the experimental class design. This research will compare the think talk write method and ordinary teaching model. The students’ would learn how to write narrative text. The population of this research was the tenth grade of SMKPGRI 3 cimahi. Therefore, the advantages of this research to invented the new teaching model to the students’, it was good for students’ development in teaching and learning English with a new model of teaching. This study uses quasi experimental design, Data from this  study collected  through pre-test and post-test, in order to find out some of the results that have increased or decreased, The results show an experimental class with  the TTW (Think Talk Write) method. The pre-test results were supported by highest score and the lowest with the highest, pre-test score of 85 while the lowest score was 52, and the post-test  score was 52 and the  post-test score  with the highest score of 93, and the lowest 70. With the pre-test and post-test researchers could compare the assessment
Students’ Motivation in Learning English
Authors: Purnama Neng Aprilia , Rahayu Neng Sri , Yugafiati Rasi
Published: November 2019

Motivation is one of the most significant things in learning process. Without motivation, the purposes of learning is tough to be achieved. When learners have it in learning process, they will more understand with the materials, especially English. The goal of this study is to know how students’ motivation in learning English of eight grade at MTs Mathla’ul Anwar Sukaguna. This study used descriptive qualitative method. The data was carried out by using a questionnaire of students’ motivation which have ten items adapted from Clement, Dornyei, & Noels (1994) and used an interview which have five questions‎. The data were processed in the percentage and descriptive explanation. The main findings described that the learners are entirety highly motivated. Based on this study’s findings, students of eighth grade at MTs Mathla’ul Anwar have that motivation, it is based on the outcome of questionnaire and interview. From the output of questionnaire, most of students choose the agree statements. It means that students has an savor in learning English. Furthermore, the yield of interview expressed that students have highly interesting in learning English. But in this case, the teacher have to be more creative in using the media, strategy, or delivered material in teaching learning activity to improve students’ motivation.
Students' Speaking Anxiety in EFL Classroom
Authors: Asysyfa Asysyfa , Handyani Ayu Maulidia , Rizkiani Siska
Published: November 2019

This study investigated the students’ speaking anxiety in the first grade of vocational high school. It emphasized on the level, the causal factors and the strategy to reduce the anxiety. It applied descriptive qualitative to answer the research questions. The data were obtained through questionnaire and interview. The Foreign Language Classroom Anxiety Scale (FLCAS) questionnaires and interview were administered to 30 students. It was revealed that [a1] the factors that make students feel anxious in speaking in English were lack of preparation, afraid of left behind in understanding the material or what the teacher talks about, afraid of making mistakes, afraid of being laughed by his/her friends, unconfident to spell, pronounce and select the words in English. It was also found that there were eight students in level Relaxed, twelve students in level Mildly Anxious, and ten students in level Anxious. Last, the strategies that students should do to reduce their anxiety are do more preparation before speaking, try to be more confident in saying English words, and pronunciation practice. Keywords:   Speaking, Speaking anxiety, EFL Classroom. [a1]It was revealed that
AN ANALYSIS DEIXIS IN RIDWAN KAMIL’S SPEECH AT THE ASIA AFRICA CONFERENCE (KAA)
Authors: Asmarita Aas , Haryudin Acep
Published: November 2019

The central topics of pragmatics, this study is limited on applying deixis on speech Ridwan Kamil at the Asia Africa Conference (KAA). This research deals with the English deixis. The objectives of this study are to analyze type of deixis and to find out the most dominant type of deixis in “Ridwan Kamil’s speech  at Asia Africa Conference (KAA)” on April 24th 2015. This study was conducted by using qualitative approach. From the five type of deixis, in Ridwan Kamil’s speech found that there are three types of deixis, namely person deixis (7 data) time deixis (3 data), and the last is social deixis (1 data). From the analysis of deixis, it was also revealed that person deixis as the most dominant type which was found on speech Ridwan Kamil at the Asia Africa Conference. Keywords:  Deixis, Asia Africa Conference (KAA), Speech
Authors: Tampubolon Fitri Mariana , Hasibuan Ahmad Basid
Published: November 2019

Penelitian ini bertujuan untuk mengevaluasi adanya pengaruh komitmen organisasi, kompetensi sumber daya manusia dan pemanfaatan teknologi informasi terhadap kualitas laporan keuangan Pemerintah Daerah di wilayah Provinsi DKI Jakarta. Penelitian ini merupakan penelitian kuantitatif dengan sumber data primer berupa kuesiner. Metode pengambilan sampel data adalah dengan menyebarkan kuesioner dengan jumah kuesioner yang dibagikan sebanyak 95 dan kuesioner yang digunakan sebanyak 84. Analisis data dilakukan dengan model regresi linier berganda dengan software SPSS versi 25.00. Hasil penelitian ini berdasarkan uji regresi linier berganda dan uji t menunjukkan bahwa komitmen organisasi berpengaruh positif tetapi tidak signifikan terhadap kualitas laporan keuangan Pemerintah Daerah Provinsi DKI Jakarta, kompetensi sumber daya manusia berpengaruh positif dan signifikan terhadap kualitas laporan keuangan Pemerintah Daerah Provinsi DKI Jakarta sedangkan pemanfaatan teknologi informasi berpengaruh negatif dan tidak signifikan terhadap kualitas laporan keuangan Pemerintah Daerah Provinsi DKI Jakarta.
Relationship Between Hope, Religiusity, Social Support, Resiliency And Subjective Well Being
Authors: Munawaroh Eem , Muslikah Muslikah , Suharso Suharso , Rosdiana Gesti
Published: November 2019

This study aims to examine a relationship between hope, religiosity, social support, resilience and subjective well being of 455 bidik misi students University Negeri Semarang.. The research method used was correlation with random sampling as sampling technique. The data was collected by 5 scale they are hope scales using the expectation scale for adult cognitive models from Snyder, social support scales using multidimensional scales of perceived social support, subjective scales using oxford happines inventory, resilience scales using resilience scales from Reivich and Sheite, whereas religiosity was measured using the scale of religiosity. To analyze the relationship, correlational product of moment parson is used. The results showed that the correlation between subjective well being and hope outcome was 0.155, the correlation between subjective wellbeing and religiosity was 0.148, correlation between subjective well being and social performance was 0.148, Correlation between subjective well being and resilience was 0.473, and there are simultaneous influence of hope, social support, religiosity and resilience, to subjective well-being. The conclusion of this study was hope, religiosity, social support, and resilience is a predictor of subjective well being.
Metaphor Counseling and Students Responsibility on Elementary School
Authors: Mashar Riana , Nurihsan Juntika
Published: November 2019

The research aimed to figure out the effect of metaphor counseling in STAR KIDS (Story Teach Responsibility for Kids) module toward the responsibility of 6-7-year-old students of the first grade of elementary school. The research used untreated control group design by providing pretest and posttest sample design. The research subject consisted of 21 students in the experimental group and 26 students as the control group. The responsibility data collection performed by using observation guideline checklist, which quantified in the interval scale. SPM Raven scale measured the children's bits of intelligence. The STAR KIDS treatment is given in 15 meetings. The results of the pretest and posttest were analyzed by using Anacova analysis technique through SPSS 17 for Windows. The research result showed that (1) students of experiment group who received STAR KIDS metaphor counseling showed higher responsibility increase rather than students of a control group who did not receive the treatment, (2) The intelligence of the students did not show the effect on the effectiveness of counseling metaphor.
Emotion Focused Coping in Single Mother Who has Adolescence with Autism
Authors: Dina Elisabet Fransiska , Faizah Faizah , Dara Yuliezar Perwira
Published: November 2019

Single mother who has adolescence with autism have higher stress level than mothers who have normal ones and make themto do coping, one of them is emotion focused coping. The research is qualitative phenomenology based and analyzed with Miles Hubberman. Result showed most subjects tend to cope with escape (rejection and wishful thinking), social emotional support (family and environment), self control (patient), distancing (avoiding problems), positive reappraisal (pray to God) and accepting responsibility (acceptance and responsibility). Single mothers tend to cope with their own way frequently to reduce stress and when they facing their child behavior.
Oxidative Stress Induced DNA Damage and Reproductive Toxicity in Male Albino Mice Orally Exposed to Sorbitol
Authors: Alabi Okunola A. , Oladimeji Lanre R. , Sorungbe Adewale A. , Adeoluwa Yetunde M.
Published: November 2019

In this study, the potential DNA damage and reproductive toxicity of sorbitol was investigated using bone marrow micronucleus (MN), sperm morphology, and sperm count in mice. Five doses of 90, 45, 20, 10 and 1 mg/kg/day, defined by allometry, and approximately corresponding to 1.5g, 750mg, 330mg, 165mg and 16mg of sorbitol daily consumption by a 70kg human, respectively, were used. MN analysis showed a dose-dependent induction of micronucleated polychromatic erythrocytes and other nuclear abnormalities across the treatment groups. Assessment of sperm shape showed a significant (p < 0.05) increase in sperm abnormalities with significant (p < 0.05) decrease in mean sperm count in treated groups. The result of the oxidative stress biomarkers showed induction of significant (p < 0.05) increase in liver catalase, MDA and serum ALT and AST activities with concomitant decrease in SOD activities in exposed mice. A significant increase in weight of exposed mice were recorded when compared with the negative control. The results of this study showed the genotoxicity and reproductive effects of sorbitol.
Total Solid Content and Compound Properties from Different Collection Time of Hevea brasiliensis Latex
Authors: Junaidi  , Wijaya Andi , Rachmawan Arief , Andriyanto Mochlisin
Published: November 2019

This study compared the total solid content and compound properties of Hevea rubber latex produced from material collected during different periods. Samples were collected from five trees, with the collection replicated three times with tapping task as replication. Observed parameters included total solid content, vulcanization characteristics, technical and physical properties. The results exhibited that the longer latex flowed, the more total solid content tended to decrease. Results indicate that compound of latex collected 20 minutes (C20), 60 minutes (C60), and 300 minutes (C300) after tapping qualified for SIR 20. Other parameters did not show a significant difference among the three tested compounds. Considering the products requiring high dry rubber content, it is suggested not to blend the late collection with main collected latex.
The Effect of Tractor Driving System Type on its Slip and Rolling Resistance and its Modelling Using Anfis
Authors: Moinar Abdolmajid , Shahgholi Gholamhossein
Published: November 2019

Pulling force required for operations such as tillage is a result of the interaction between the tractor’s wheel drive and soil surface limited by various factors, such as the rolling resistance and slip of the wheel drive. In this research, the traction performance of tractors with different driving systems (four-wheel drive, rear wheel drive, and front wheel drive) was investigated. Test parameters included different tractor forward speeds (1.26, 3.96, and 6.78 km·h−1), tire inflation pressures (170, 200, and 230 kPa), ballast weights (0, 150, and 300 kg), and aforementioned driving systems, as well as required drafts (2, 6, and 10 kN). For each experiment, two indices of slip and rolling resistance were measured. The results of this study showed that the four-wheel-driving system indicated a low slip at similar pulling forces. In order to achieve a low slip, the four-wheel driving system did not necessarily need to add the ballast weight or to reduce the inflation pressure. The four-wheel driving system showed lower rolling resistance than the other two systems. Slip and rolling resistance of wheels were predicted using an adaptive neuro-fuzzy inference system (ANFIS). It was found that ANFIS had a high potential for predicting the slip (R
2 = 0.997) and rolling resistance (R
2 = 0.9893).
Mathematical Modelling of Solar Thermal Collectors and Storages
Authors: Tóth János , Farkas István
Published: November 2019

Block-oriented modelling is a powerful tool in system design. The models developed this way can be used to study various systems, such as solar thermal systems. In the work presented, main goal is to compare different mathematical models of solar thermal devices. The difference in accuracy of such models in respect to the possibilities of a hardware-in-the-loop simulation will be discussed. Two models of solar thermal collectors will be compared and used in a system containing two different heat storages in order to study the behaviour of these models. The tests were carried out in a Simulink based block-oriented environment called SimSolar.
Investigations of the Dynamics of a Four-Element Machine-and-Tractor Aggregate
Authors: Bulgakov Volodymyr , Ivanovs Semjons , Adamchuk Valerii , Antoshchenkov Roman
Published: November 2019

The paper presents a dynamic model of four-element machine-and-tractor designed on the basis of a combined soil-cultivating-sowing aggregate and a tractor with an articulated frame. The pseudo velocity of the first tractor half-frame was considered a generalised coordinate. The control impact upon the tractor was obtained by means of the bending angle of the tractor half-frames. The trajectories and movement speeds of the aggregate elements were calculated as a function of time for the driving mode along a straight-line path and the tractor movement according to the harmonic control law. By means of the measuring system, trajectories of the aggregate elements were obtained. It was established that the movement trajectories of the aggregate elements represent a complex assessment parameter of the mathematical model adequacy of the aggregate plane-parallel movement. There was found a regularity of the aggregate turning radius and the bending angle of the tractor half-frames.
Cultivation of dandelion (Taraxacum erythropodium) on coastal saline land based on the control of salinity and fertilizer
Authors: Wu Zhe , Xue Zhizhong , Li Haishan , Zhang Xiaodong , Wang Xiuping , Lu Xuelin
Published: November 2019

Dandelion (Taraxacum spp.) is a widely distributed weed; in China, however, dandelion has been considered to be a kind of medicinal and edible vegetable in recent years. This transition from weed to vegetable requires corresponding cultivation and management. Thus, the production of dandelion on saline land was conducted based on the evaluation of dandelion salt tolerance. Low soil salt content (< 0.3%) did not significantly affect dandelion growth, and the salt tolerance threshold of dandelion ranged from 0.4% to 0.43% according to the correlation between salt content and morphological and physiological parameters, which was for guiding the preparation of saline land for dandelion field cultivation. Different fertilizer treatments significantly affected the leaf yield of dandelion, and the maximum fresh leaf yield of ~10.5 t ha−1 was obtained when urea was applied in batches at a ratio of 2:2:1 in the sowing, seedling and flowering stages, respectively. This research provided the theoretical and technical support for the cultivation on saline land, laying the foundation for further study of quality control for the cultivation of dandelion on saline land.
Cognitive Pretesting and pretest of the STRAIN questionnaire to elaborate work-related stress of health care staff in Switzerland / Verständlichkeitsprüfung und Pretest des STRAIN-Fragebogens zur Erhebung der Arbeitsbelastung bei Gesundheitsfachpersonen in der Schweiz
Authors: Golz Christoph , Peter Karin Anne , Hahn Sabine
Published: November 2019

The workforce shortage in health care is a major challenge worldwide. In Switzerland, this shortage is not only demographically caused but also due to workload. Adequate measures require a good data basis. The aim of this study is to test instrument specially developed for the health professions to measure work-related stress in practice. Cognitive pretesting was used for the evaluation. Overall, 18 semi-structured single-interviews with nurses and nursing assistants were conducted. In two rounds, the question-answer-process was analysed for 11 questions. The STRAIN questionnaire was then pretested by 17 health professionals. In the first round, 42 problems were identified based on the phases of the “Cognitive Aspects of Survey Methodology”. Of these, 57 % were comprehension problems. This was shown by the polysemantic usage or unknowingness of terms. Further 38 % were problems with the answer categories, such as a missing category or an inappropriate formulation. Further questions were modified through a final pretest. The uniform comprehensibility has been achieved. Due to the questionnaire length, an online tool with a save function should be used. The results of this study are similar to those of comparable studies, which also show the most common problems with understanding. This is due to changes of concepts’ meanings over time and culture. A cognitive pretest is therefore recommended, especially for a heterogeneous target group such as health professions.