bluuebunny/crossref_metadata_2025 huggingface dataset:
Eficácia dos exercícios com bola suíça aplicados previamente à radioterapia para câncer mama
Authors: Mariano Karina Oliveira Prado , Diniz Maria de Fátima Pinheiro Pessanha , Silva Adriana Teresa , Silva João Herivelton Campos , Vasconcelos Luciana Auxiliadora de Paula , Branco Marcelo
Published: February 2020

Objetivo. Verificar a eficácia dos exercícios com bola suíça aplicados previamente à radioterapia para câncer de mama. Método. Estudo clínico, randomizado, controlado, paralelo e cego. Participaram 13 mulheres com idade de 45 a 67 anos que fizeram a primeira cirurgia por carcinoma invasivo de mama unilateral e as que tinham indica­ção para o tratamento radioterápico. Foram divididas em dois grupos: controle, que recebeu apenas um folheto explicativo sobre a radiote­rapia (GC=7) e tratado, que recebeu um folheto explicativo sobre a radioterapia mais tratamento com exercícios na bola suíça (GT=6). Foram avaliadas pelos questionários, FACT-B, escala DASH e o In­ventário de Depressão de Beck. Os pacientes receberam 20 sessões de fisioterapia no qual foram realizados exercícios ativos livres para membros superiores utilizando a bola suíça, previamente a radiote­rapia, por 30 minutos. A análise estatística foi realizada por meio de Teste t pareado e não pareado. Resultados. Houve diferença no BDI na comparação intragrupos (p=0,02) e intergrupo GT (p=0,01), no FACT-B, no intergrupo GT (p=0,05). Na DASH ambos os grupos tiveram melhora quantitativa no final da avaliação, embora não sig­nificativa. Conclusão. Concluiu-se que a realização de exercícios com bola suíça previamente a radioterapia promoveu benefícios psicológi­cos e na qualidade de vida.
Uso da realidade virtual no tratamento fisioterapêutico de indivíduos com Síndrome de Down
Authors: Mello Bruna Cavalcanti de Carvalho , Ramalho Tayse Figueiredo
Published: February 2020

Introdução. A Síndrome de Down (SD) é uma anormalidade genéti­ca que tem como achado mais frequente a hipotonia muscular gene­ralizada e como consequência alterações de equilíbrio dinâmico e de controle postural. A fisioterapia deve atuar precocemente, entretanto, o longo tempo necessário e a pouca motivação gerada pelos métodos tradicionais são apontados como motivo de abandono terapêutico. A Realidade Virtual (RV) surge como instrumento que adiciona um ob­jeto lúdico à terapia e favorece a participação ativa do paciente durante o tratamento. Objetivo. Verificar o que consta na literatura a respeito do uso da RV como auxiliar no tratamento de crianças e adolescen­tes com SD. Método. O presente estudo consistiu em uma revisão de literatura sobre o uso da RV em crianças e adolescentes com SD, realizada entre os meses de junho e setembro de 2013 nas bases de dados eletrônicas Medline, Lilacs, PEDro, Scielo e Google Scholar. Resultado. Foram encontradas 4 publicações que se enquadravam nos critérios de inclusão estabelecidos e todas apresentaram benefícios sig­nificativos do uso da RV nas alterações sensório-motoras em crianças e adolescentes com SD. Conclusão. Foi possível sugerir que a RV é apontada como uma importante ferramenta coadjuvante no trata­mento fisioterapêutico em crianças e adolescentes com SD.
Oxidized-ATP Attenuates Kidney Allograft Rejection By Inhibiting T-Cell, B-Cell, and Macrophage Activity
Authors: Ding Xiang , Wilson Nancy A. , Redfield Robert R. , Panzer Sarah E. , Verhoven Bret , Reese Shannon R. , Zhong Weixiong , Shi Lei , Burlingham William J. , Denlinger Loren C. , Djamali Arjang
Published: February 2020

Background

Extracellular ATP binds to purinergic receptors and promotes inflammatory responses. We tested whether oxidized ATP (oATP), P2X7 receptor antagonist can attenuate acute kidney allograft rejection.

Methods

Brown Norway kidney allografts were transplanted into Lewis recipients. Three groups were defined: oATP (n=8), cyclosporine A (n=6), and no treatment (n=8). On day 7, we assessed kidney allograft survival, function, and rejection characteristics. We further determined T-cell, B-cell, and macrophage response to oATP in vivo and in vitro and examined intragraft inflammatory gene transcripts.

Results

Kaplan–Meier survival analyses demonstrated significantly better graft survival rates in oATP and CsA groups compared with no treatment (P<0.05). Similarly, serum creatinine (Scr) and BUN levels were significantly lower in oATP and CsA groups (P<0.05). oATP reduced both T cell–mediated rejection and antibody-mediated rejection, inhibited B-cell and T-cell activation, and downregulated intragraft IL-6 mRNA levels (P<0.0001). In vitro, oATP prevented proliferation in mixed lymphocyte reaction assays, and inhibited macrophage P2X7R activity in a dose-dependent manner.

Conclusions

Our findings suggest that oATP mitigates kidney allograft rejection by inhibiting T-cell, B-cell, and macrophage activity and indicate a potential role for the purinergic system and oATP in solid organ transplantation.
Immune Checkpoint Inhibitor Nephrotoxicity: Update 2020
Authors: Gupta Shruti , Cortazar Frank B. , Riella Leonardo V. , Leaf David E.
Published: February 2020

Immune checkpoint inhibitors (ICPIs) have transformed the landscape of oncology, but are associated with a variety of autoimmune adverse events, including AKI. ICPI-associated AKI (ICPI-AKI) is emerging as an increasingly frequent cause of AKI in patients with cancer, and poses unique diagnostic and management challenges to clinicians who care for these patients. In this review, we describe the incidence and risk factors for ICPI-AKI, including proton pump inhibitor use, CKD, and combination immunotherapy. We discuss the limitations of the various definitions used for ICPI-AKI in prior studies, and propose a novel classification system (definite, probable, and possible ICPI-AKI) that recognizes the diagnostic uncertainty inherent in many cases. We discuss the key clinicopathologic features and treatment strategies for ICPI-AKI, including the role of kidney biopsy versus empirical treatment with steroids. We also explore the under-studied area of ICPI use in the setting of solid organ transplantation, where nephrologists and oncologists must balance the risk of rejection versus treating the underlying malignancy. Finally, we summarize existing data on the role of ICPI rechallenge after an episode of ICPI-AKI.
ASSOCIATION OF C677T POLYMORPHISMS OF MTHFR GENE WITH RECURRENT PREGNANCY LOSS IN VIETNAMESE WOMAN
Authors: Le Thanh Nha Uyen , Ha Thi Minh Thi , Nguyen Viet Nhan
Published: February 2020

Background: Recurrent pregnancy loss is a major concern in gynecology. Recently, many papers have showed the role of genetic factors in etiology of recurrent pregnancy loss. Several published studied revealed that C677T polymorphism is a high risk of recurrent pregnancy loss. However, this finding is still controversy. Therefore, this study is aimed at investigating the association of C677T polymorphisms of MTHFR gene with recurrent pregnancy loss in Vietnamese woman.
Methods: Study subjects comprised 100 healthy women (control group) and 52 women with recurrent pregnancy loss. C677T polymorphisms were identified by PCR-technique.
Results: The frequency of 677CC, 677CT, and 677TT genotypes in Vietnamese women with recurrent pregnancy loss is 65.4%, 30.8%, 3.8%, respectively; while the distribution of those genotypes in the control-group is 86%, 12%, và 2% (χ2 = 8.83; p = 0.012). Statistic analysis revealed that MTHFR C677T polymorphismsare associated with recurrent pregnancy loss (for CT vs. CC: OR= 3.37, 95%CI: 1.44 – 7.87, p = 0.0049; for (677CT + 677TT) vs. CC: OR= 3.25, 95%CI: 1.46 – 7.26, p = 0.004; for T vs. C: OR= 2.74, 95%CI:1.55 – 5.55, p = 0.005).

Key words: Recurrent pregnancy loss, C677T polymorphisms, MTHFR gene
PROGNOSTIC VALUE OF COMBINATION AIMS65 AND MELD SCORES IN CIRRHOTIC PATIENTS WITH ACUTE VARICEAL BLEEDING
Authors: Nguyen Thi Nhung , Phan Trung Nam , Tran Van Huy
Published: February 2020

Bacground: Variceal bleeding is a severe complication of portal hypertension due to cirrhosis with high rate of motality, hence, predicting early rebleeding and mortality in cirrhotic patients with acute variceal bleeding is vital in clinical practice.
Objectives: To evaluate the prognostic value of the combination of AIMS65 and MELD scores in predicting first 5 days in-hospital rebleeding and mortality in cirrhotic patients with acute variceal bleeding.
Materials and Methods: 44 cirrhotic patients with acute variceal bleeding hospitalized at Hue Central Hospital. MELD and AIMS65 scores were calculated within the first 24 hours and monitoring rebleeding and mortality in the first 5 days in these patients.
Results: AIMS65, MELD scores can predict first 5 days rebleeding and mortality with AUROC are 0.81, 0.69 and 0.92, 0.95, respectively. Combination of AIMS65 and MELD scores can predict first 5 days in hospital rebleeding with AUROC is 0.84, sensitivity 83.3%, specificity 81.6% (p<0.001) and mortality with AUROC is 0.96, sensitivity 100%, specificity 92.7% (p<0.001).
Conclusions: The combination of AIMS65 and MELD scores increased the sensitivity, specificity and prognostic value in predicting first 5 days in-hospital rebleeding and mortality in cirrhotic patients with acute variceal bleeding in compare to each single scores.

Key words: AiMS65 score, MELd, acute variceal bleeding
TRANSANAL TOTAL MESORECTAL EXCISION OF RECTAL CANCER TREATMENT
Authors: Tran Viet Hung , Pham Anh Vu , Pham Nhu Hiep , Ho Huu Thien , Phan Hai Thanh , Pham Xuan Dong
Published: February 2020

Purpose: To evaluate the early results of the feasibility and safety on technology and oncologic transanal total mesorectal excision (down to up).
Materils and method: Prospective study from 2012 to 2018.
Patients: 23 rectum adenocarcinoma staging T ≤ 3, N ≤ 1, M0 were operated using one of two modalities Hybrid NOTES (A) and NOTES (B).
Results: Twenty three patients with Rectal cancer were sucessfully in total mesorectal excision performed by Hybrid NOTES and NOTES procedures. Three cases in group NOTES had per-operative complications such as bleeding or urethra injury required one or two trocarts for assistance, no conversion to open surgery and no mortality. The operation time: group A (Hybrid NOTES): 190 ± 47 (120-280) mins; group B (NOTES): 258 ± 40 (190-300) mins. The hospital stay: 9 ± 2.7 (4-19) day.
Conclusions: transanal total mesorectal excision (down to up) endoscopic surgery (NOTES) and Hybrid NOTES is feasible and safe.However, a study in a large number of patient and long follow-up is necessary.

Key words: Mesorectum, Natural orifice transluminal endoscopic surgery (NOTES), Hybrid NOTES, rectal cancer
АНТРОПОНІМІКОН У ПОЕЗІЇ ЄВГЕНА МАЛАНЮКА: СЕМАНТИКО-СТИЛІСТИЧНИЙ АСПЕКТ
Authors: Демешко І. М.
Published: February 2020

Functional and stylistic peculiarities of the anthroponyms of Ye. Malaniuk’s poetry are investigated, their role in expressing the basic idea, in particular the specificity of anthroponyms usage in Ye. Malaniuk’s poetry is described, their contextual and functional text-forming essence is established, and functional and stylistic features are revealed, the situations of application of models against the background of the era and genre are analyzed. The influence of onims on the perception of images by the reader is investigated, the peculiarities of the poet's idiolect through the prism of proper names are determined. The use of anthroponyms has been found to create associative connections that extend the space of poetry, help the writer to express himself more fully and to connect with the reader.

The anthroponymic material describes individual author’s features of name creation and use, describing their role in expressing the main idea. Anthroponyms, which are constituent elements of artistic text, represent the specificity of a work of verbal art as a system. Ye. Malaniuk’s works are a valuable treasure of Ukrainian culture in which onims are its integral parts.

It is revealed that anthroponyms form and represent in a complex their own onim space in literary and artistic work and in all creative achievements of the artist. The state historiophysical concept defined the organization of Ye. Malaniuk’s texts at all studied levels. The anthroponymicon used by the writer is organized into the following thematic groups: artists, historical figures, mythological and biblical characters, literary characters, contemporaries, and the author's anthroponyms. The studied units represent significant national and cultural components and at the same time fulfil an artistic and evaluative function in the vast majority of its texts. Literary anthroponyms, along with other means, generate intellectualism as one of the specific feature of individual author’s handwriting. A systematic analysis of onim Ye. Malanyuk’s poetics and understanding of the language as an integral science is a contribution to extensive works on the literary onomastics.
«ПРИКЛЮЧЕНИЯ ПИНОККИО» КАРЛО КОЛЛОДИ И ИТАЛЬЯНСКАЯ КОМЕДИЯ ДЕЛЬ АРТЕ. В ПОМОЩЬ УЧИТЕЛЮ НАЧАЛЬНЫХ КЛАССОВ
Authors: Козорог О.В. , Константінова Л. В.
Published: February 2020

The article explores the world-famous work of the Italian writer Carlo Collodi The Adventure of Pinocchio. Despite the fact that the book of Carlo Collodi is addressed to a children's audience, it contains features of satire on Italian reality. The book The Adventures of Pinocchio by Carlo Collodi throws us back to folk laughter culture (term of M. Bakhtin), which is inseparably linked with the traditions of the Italian comedy dell’arte. Just in it Collodi draws the plot for his work. In the book about the adventures of Pinocchio, there is a lot from the carnival laughter culture and from the farce theater in particular. This includes scenes of fights, denudation, buffoonery, throwing various objects by literary characters into each other, dousing the main character with water or sewage, the unprecedented gluttony of the fairy tale characters, their ridicule and humiliation, grotesque exaggeration of appearance, as well as other methods of folk farce. Collodi’s “rhinology” (term of V. Vinogradov) belongs to the world of carnival laugh culture. Mask Medico della Peste (“plague doctor”) with a large bird’s beak is one of the main places in the Italian comedia dell’arte. And the Italian proverb “Who he lies, his nose grows” in some way explains the magical episodes of Pinocchio’s “rhinology” related to the expansion of his nose to huge sizes at those moments when the main character of the fairy tale begins to lie. The book about the wooden man was widely known and recognized in literary circles, and its main character Pinocchio became the prototype of Burattino by Alexei Tolstoy.
ИСПАНСКАЯ ТЕМА В РАССКАЗАХ Э. ХЕМИНГУЭЯ «ПОБЕДИТЕЛЬ НЕ ПОЛУЧАЕТ НИЧЕГО»
Authors: Разуменко Т.О.
Published: February 2020

Ernest Hemingway is a symbolic figure in the literature of the 20th century. His name and works entered the history of world literature forever. The purpose of the article is to characterize the way of opening the inner world and the emotional state of the characters, the psychology of the ‘lost generation’ in the interaction of its external and internal manifestations through the civil war inSpain. The article analyzes the stories ‘A clean, well-lighted place’, ‘A way you’ll never be’, ‘The light of the world’.

The heated atmosphere of the ‘bloody decade’ introduced new themes into the writer's work.Spainbecame a ‘moment of truth’ for E. Hemingway. He feels the inevitability of the coming world war. E. Hemingway expressed himself inSpaincompletely as an artist, and as a citizen. All the characters of his stories are simple people, men and women, unemployed, traumatized by war, looking for their place in the post-war world (a cook, a lumberjack, Indians, prostitutes etc.). Endless humor, laughter, self-irony, joke, and sometimes bitter laughter help them to stand and find their place in life.

The ‘code’ of light, purity, and peace are universally introduced into all writer's works. In the personality of his characters there is much in common, unifying them with all the differences in appearance and life path, and above all, hopelessness and disappointment, indifference to life in general, and the most terrible is their loneliness. The utmost frankness and genuineness of soul movements, the combination of morals, history, nature with the chronicle of only human destiny, are exceptionally bright creative personalities of E. Hemingway, who describes his characters.

In our work we came to the conclusion that the characters of the stories about the war years inSpain‘A clean, well-lighted place’ (about a lonely old man), ‘A way you’ll never be’ (about the war), ‘The light of the world’ (the sad and ironic story about prostitutes who remembered the past) anyway are rejected by a prosperous society. Hopelessness, dark state of the soul of ‘lost generation’ are combined with the belief in the ‘ordinary’ life without the war for the characters of E. Hemingway’s stories. Light and dignity are the main components of a person’s peaceful life, the confession of a person who got out of the abyss and survived during the war, but who lost the sense of life in peacetime, they are distinguishing features of many characters in military conflicts.
ІНФОРМАЦІЙНО-ЦИФРОВА КОМПЕТЕНТНІСТЬ МАЙБУТНІХ УЧИТЕЛІВ ІНОЗЕМНОЇ МОВИ ЯК КЛЮЧОВА ВИМОГА НОВОЇ УКРАЇНСЬКОЇ ШКОЛИ
Authors: Черненко А. В.
Published: February 2020

The use of information and communication technologies in the educational process today is one of the main tools for ensuring the success of New Ukrainian School. The importance of introducing modern ICT into the educational process is due to the need to the formation of the information and digital competence of foreign language teachers, which is recognized as one of the key competencies. It reflects the research topicality. The article is devoted to the problem of forming one of the important competences of foreign language teachers - information and digital.The purpose of the article is an analysis of the use of information and communication technologies by foreign language teacher and their influence on the formation of information and digital competence. To achieve the purpose the general theoretical scientific methods are used such as analysis, synthesis and systematization of researchers’ works where the problem of the information and digital competence is described; logical-systemic, problem-targeted, comparative analyses as for theoretical basics of the peculiarities of ICT using. There are some research results. The competence approach concept in the educational process at a current stage of educational sphere reformation was revealed. The main functions of information and communication technology using in the educational process and possibilities of its successful using were mentioned. The ICT tools classification according to their application in teachers’ activity was proposed. The formation of information and digital competence in foreign languages future teachers, as a core component in current educational process was indicated. The article contains the characteristics of skills necessary for the successful formation of information-digital competence and a set of activities for teaching foreign languages with the help of ICT. The particular attention was paid to the ICT using at foreign languages classes that gives new opportunities to pupils, as well as supports teachers to solve some didactic tasks. The ways of ICT using according to the need of the specific lesson were presented. Also the advantages and disadvantages of ICT using at foreign language lessons were discussed.
СПЕЦИФІКА ВИКОРИСТАННЯ ПЕДАГОГІЧНИХ ТЕХНОЛОГІЙ ПРИ ВИКЛАДАННІ ЕКОНОМІЧНИХ ДИСЦИПЛІН
Authors: Шпак I. О.
Published: February 2020

The current state of the development of Ukraine poses new requirements for the training of specialists. The task solution is related to improving the quality of economic education of specialists in all sectors of the society. With this in mind, improving the effectiveness of teaching economics in educational institutions of any level and profile is of particular value. The purpose of the article is to analyze the peculiarities of the use of pedagogical technologies in the process of teaching economic disciplines to students of higher education institutions. To achieve this purpose, such common scientific methods of research are used: analysis, synthesis, systematization, comparison, generalization in order to determine the specifics of the use of modern pedagogical technologies in the study of economic disciplines by students of higher education institutions.

It has been found that the widespread use of pedagogical technologies began in the early 60s of the XXth century. This process was related to the reform of the American and European school. As it is known, the concept "pedagogical technology" was introduced to the scientific circulation for the first time in the USA.

Today, the issue of determining the essence of pedagogical technologies, their classification and peculiarities of using them in teaching educational disciplines is envisaged in works of domestic scholars (V. Bespalko, V. Boholiubova, T. Ilina, M. Klarin, Z. Malkova, M. Nikandrov, Ye. Polat, H. Selevko, V. Chuprusov) and foreign ones (Anderson, J. Blok, B. Blum, R. Meidzher, etc.).

According to the results of the research, scholars, who state the fact of the need to use pedagogical technologies in teaching economic disciplines in higher education institutions, express different points of view on this issue, which are significantly complementary. It is also important to consider scholars’ conclusions about the peculiarities of the use of pedagogical technologies in the activities of higher education institution in the process of teaching economic disciplines.

Therefore, a modern pedagogical technology is a set of methods of pedagogical influence, involves specific techniques, methods, means. Effective use of pedagogical technologies in teaching subjects of the economic cycle helps the teacher to get a more effective result in teaching students and to enjoy the activities.
PSYCHOLOGICAL FEATURES OF THE CITY IMAGE (ON THE EXAMPLE OF KHARKIV)
Authors: Кудрявцев К. , Поденко А. , Башкатова С. , Ходєєва А. , Павлікова В.
Published: February 2020

Aim of the study – to determine the psychological specific features of the city image among the respondents depending on the age and experience of living in a city.
Research Methods and Sample. The study of the city image has been carried out through the semantic differential to assess the perception of the city image «City in the perception of the residents» (O. E. Pronina, N. S. Goncharova, 2016). Scale to assess the degree of compliance of an ideal city image and the city of residence of personality by O. S. Shemelina and O. E. Tsigankova (2016) was used to determine the difference between the image of the ideal city and the city of Kharkiv. The respondents were originally asked to assess the image of an ideal city and then the image of Kharkiv on two separate forms. It was further analyzed the differences in evaluation of descriptors subject to the variation vector of the real image of a city and the ideal one.
Results. In contrast to the older age group, students characterize the city image of Kharkiv to a greater extent through such descriptors as «womanly», «dirty», «boring», «ugly», «monotonous», «dull-witted», while mature respondents more frequently estimate it as «manly», «clean», «interesting», «beautiful», «motley», «witty».
Conclusions. The experience of living in the hometown has a positive effect on the assessment of its image since the residents of Kharkiv describe it as more positive compared to visitors. In addition the residents’ city image coincides with the image of an ideal city by a larger number of parameters. The city image within the students generally is more critical and distant from the ideal compared to older respondents. The cumulative effect of the respondents’ age and their territorial belonging, that determines the experience of living in the city, reflects on the indicators of its friendship, warmth, beauty, naturalness, humanity and inspiring effect. The city image among the visiting students has negative descriptors as the dominant - aggressive, cold, ugly, artificial, officious and suppressing.
Comparison of functional properties of woven and knitted denim fabrics
Authors: JAMSHAID HAFSA , WAQAR RAJPUT ABDUL , ZAHID BILAL , ASFAND NORINA , ABBAS BASRA SIKANDER , ALI AMER
Published: February 2020

The study was aimed to develop a knitted denim fabric and investigate its properties. The said fabric has similar visualappearance to the woven denim fabric, offering additional stretch properties. The twill effect was produced on circularknitting machine using cross terry structures. Woven denim fabric was also produced to compare its properties withknitted denim. The Physical and comfort properties of these fabrics like air permeability, thermal resistance and moisturemanagement, were investigated. Experimental investigation of serviceability i.e Pilling was also carried out. The purposeof study is to compare both woven and knitted denim fabric properties.
ВЫБОР ТИПООБРАЗУЮЩИХ ОПЕРАЦИЙ ПРИ КЛАССИФИКАЦИИ ЖЕЛЕЗНОДОРОЖНЫХ СТАНЦИЙ
Authors: Пазойский Ю.О. , Pazoisky Yu.O. , Савельев М.Ю. , Saveliev M.Yu. , Куртикова Э.Р. , Kurtikova E.R.
Published: February 2020

Статья посвящена вопросу определения типообразующих операций, которые являются базовыми при расчете конкретного типа железнодорожной станции: промежуточная, грузовая, участковая, сортировочная, пассажирская, зонная пригородная пассажирская, межгосударственная. На основе типизации обосновываются способы использования исходных данных для классификации их производственных условий и статусных ролей. В зависимости от типа железнодорожной станции определяются следующие параметры: уровень оснащенности техническими средствами, штатное расписание, тип информационной системы и уровень автоматизации и другие. Группа типообразующих операций определяется с использованием метода экспертных оценок.
ТРАНЗИТНЫЙ ПОТЕНЦИАЛ - РЕЗЕРВ ДИНАМИЧНОГО И ИННОВАЦИОННОГО РАЗВИТИЯ ВНЕШНЕТОРГОВЫХ ПЕРЕВОЗОК РОССИИ
Authors: Гагарский Э.А. , Gagarskiy E.A. , Кириченко С.А. , Kirichenko S.A. , Забоев А.И. , Zaboev A.I.
Published: February 2020

Рассмотрены проблемы роста объемов транзитных перевозок через морские порты России, развития перевозок транспортно-технологическими системами и повышения качества транспортного обслуживания с учетом цифровых технологий.
ВЛИЯНИЕ ТРАНСПОРТНО-ЛОГИСТИЧЕСКОЙ ИНФРАСТРУКТУРЫ ФЕДЕРАЛЬНЫХ ОКРУГОВ НА СОЦИАЛЬНЫЕ ПОКАЗАТЕЛИ РОССИЙСКОЙ ФЕДЕРАЦИИ
Authors: Попов П.В. , Popov P.V.
Published: February 2020

Показано влияние логистической инфраструктуры федеральных округов Российской Федерации на ключевые социальные показатели страны. В результате проведенного исследования определены объекты инфраструктуры для каждого федерального округа, оказывающие наибольшее влияние на социальные показатели. Для каждого объекта оценена степень влияния, а также их значимость. Показано, что развитие водной и аэропортовой инфраструктуры приводит к наибольшему изменению зависимых переменных.
НАДЕЖНОСТЬ АВТОМОБИЛЬНЫХ ЭЛЕКТРОГИДРАВЛИЧЕСКИХ ФОРСУНОК С ПЬЕЗОПРИВОДОМ
Authors: Кривцов С.Н. , Krivtsov S.N. , Кузакова В.В. , Kuzakova V.V.
Published: February 2020

Работа посвящена определению эксплуатационной надежности элементов электрогидравлических форсунок с пьезоприводом. Аналитически сгруппированы элементы инжектора по функциональному назначению и определены вероятности их отказа в эксплуатации. Для каждого элемента построены плотности распределения вероятности отказов, а также подобран закон распределения и определены статистические характеристики. На основании проведенных исследований определена оптимальная периодичность контроля технического состояния электрогидравлических форсунок с пьезоприводом.
СТРАТЕГИЧЕСКИЕ ОРИЕНТИРЫ В ПЛАНИРОВАНИИ И УПРАВЛЕНИИ РАЗВИТИЕМ ЭКОНОМИКИ РОССИИ
Authors: Персианов В.А. , Persianov V. A. , Королевская В.И. , Korolevskaia V.I.
Published: February 2020

В статье дается общая оценка экономического положения страны до начала и в ходе рыночных реформ. Необходимость стратегического государственного планирования в России признается на правительственном уровне, но реализация этого решения отложена на несколько лет. Рассмотрен комплекс вопросов, включающих ситуационный анализ, виды и механизмы планирования и регулирования, отраслевой опыт стратегического планирования на примере железнодорожного транспорта.
СТРАТЕГИЯ РАЗВИТИЯ МИРОВОЙ АЭРОКОСМИЧЕСКОЙ ИНДУСТРИИ В КОНТЕКСТЕ ПРИМЕНЕНИЯ ПРОМЫШЛЕННЫХ ЦИФРОВЫХ ПЛАТФОРМ
Authors: Раткин Л.С. , Rathkeen L.S.
Published: February 2020

Рассматриваются перспективы развития мировой аэрокосмической индустрии в контексте применения промышленных цифровых платформ, репозиторных комплексов, компьютерной стеганографии и блокчейнтехнологий. Автором предложен ряд методов, повышающих эффективность функционирования репозиториев с использованием инновационных информационных технологий, запатентованных в России и за рубежом.
ОРГАНИЗАЦИЯ РАБОТЫ ХОЗЯЙСТВУЮЩИХ СУБЪЕКТОВ ЖЕЛЕЗНОДОРОЖНОГО ТРАНСПОРТА ПО ПРИНЦИПУ «ОДНОГО ОКНА»
Authors: Магомедова Н.М. , Magomedova N.M. , Супрун Е.Е. , Suprun E.E.
Published: February 2020

Организация работы хозяйствующих субъектов железнодорожного транспорта требует новых подходов и одним из них является принцип "одного окна", который позволяет ускорить процесс перевозки и доставки грузов "от двери до двери".
ТРАНСПОРТНО-ЛОГИСТИЧЕСКОЙ ИНФРАСТРУКТУРЫ ФЕДЕРАЛЬНЫХ ОКРУГОВ НА ЭКОНОМИЧЕСКИЕ ПОКАЗАТЕЛИ РОССИЙСКОЙ ФЕДЕРАЦИИ
Authors: Попов П.В. , Popov P.V.
Published: February 2020

Статья посвящена решению актуальной задачи оценки влияния транспортно-логистической инфраструктуры федеральных округов Российской Федерации на ключевые экономические показатели страны. Для проведения исследования были выбраны значения показателей основной и обеспечивающей составляющей логистической инфраструктуры за 2004-2016 гг. Для исключения избыточных независимых переменных была проведена их проверка на соответствие распределения значений в выборке нормальному закону, а также на мультиколлинеарность. В результате исследования определены предикторы логистической инфраструктуры, оказывающие существенное влияние на экономические показатели Российской Федерации, а также степень их влияния.
РАЗВИТИЕ ТРАНСПОРТНОГО КОРИДОРА «СЕВЕР-ЮГ» КАК СТРАТЕГИЧЕСКАЯ ЗАДАЧА
Authors: Куренков П.В. , Kurenkov P. V. , Белозёров В.Л. , Belozerov V.L. , Малышева О.В. , Malysheva O.V. , Элларян А.С. , Ellaryan A.S. , Астафьев А.В. , Astafiev A.V. , Мухамадшоев Ф.К. , Muhamadshoev F.K.
Published: February 2020

Исследуется поиск наиболее экономических путей трансконтинентального сообщения, связывающих Европу и Россию со странами: Индией, Южной Азии и Персидского залива. Рассматривается развитие транспортного коридора «Север Юг» в международном согласованном строительстве объектов транспортной, таможенной и пограничной инфраструктуры, обеспечивающих интеграцию евроазиатских транспортных систем, а также в целях повышения конкурентоспособности российских товаропроизводителей и предприятий.
ОЦЕНКА ЭФФЕКТИВНОСТИ АВТОБЛОКИРОВКИ В ЗАВИСИМОСТИ ОТ РАЗМЕРОВ ДВИЖЕНИЯ ОДНОПУТНЫХ ЖЕЛЕЗНОДОРОЖНЫХ ЛИНИЙ
Authors: Намжилдорж Намсрай , Namzhildorzh Namsray , Дмитренко А.В. , Dmitrenko A.V.
Published: February 2020

Рассматривается эффективность автоблокировки для повышения пропускной способности однопутных линий за счет возможности одновременного нахождения на перегоне двух и более поездов. Эффективность автоблокировки зависит как от размеров движения однопутных линий, так и от протяженности перегонов. Только при повышенных размерах движения автоблокировка позволяет сокращать суммарные задержки поездов в пути следования по однопутным железнодорожным линиям.
TACKLING MENTAL HEALTH IN SAUDI ARABIA IN THE LIGHT OF CONSIDERATION OF THE LIFE COURSE EPIDEMIOLOGICAL ISSUES
Authors: Sayed Anwar A.
Published: February 2020

Mental health disorders have started to increasingly become a public concern with more resources and efforts are being put to promote awareness and fight stigmas associated with it. Depression represents one of the most common mental health disorders with a great economic and social burden both globally and in Saudi Arabia. This study focuses on addressing depression in Saudi Arabia. The epidemiology of depression in Saudi Arabia is described using Bellingham-Young basic principles model, describing the issue from the perspectives of who; when; where; what and why. The causes of depression among patients in Saudi Arabia is described in this study, mainly in relation to chronic diseases, age and gender. Next, several approaches are suggested to tackle depression among its patients in Saudi Arabia. These approaches are described according to Ritsatakis and Jarvisalo variation of the established Dahlgren and Whitehead stages model. Lastly, depression is discussed in the light of consideration of the life course epidemiological issues and how life events may affect the development of depression in adulthood.

KEYWORDS: Depression – Life Course Issues - Mental Health – Tackling Approaches - Saudi Arabia
ИССЛЕДОВАНИЕ ПЛОДОВО-ЯГОДНОГО СЫРЬЯ САДОВЫХ КУЛЬТУР В ЦЕНТРАЛЬНО-ЧЕРНОЗЕМНОМ РАЙОНЕ ДЛЯ ПРОИЗВОДСТВА МОРСОВ И НАПИТКОВ ФУНКЦИОНАЛЬНОГО НАЗНАЧЕНИЯ
Authors: Е.А. Соломатина , Н.М. Соломатин , В.Н. Сорокопудов
Published: February 2020

Анализ потребления населением России плодов и ягод садовых культур показывает, что структура питания не соответствует современным представлениям нутрициологии. Структура питания характеризуется повышенной калорийностью, недостаточным потреблением макро- и микронутриентов. Основным источником антиоксидантов являются плоды, ягоды и овощи, так как только они способны синтезировать биофлавоноиды и другие полифенольные соединения. Перспективно использование плодов местных растительных ресурсов людям, проживающим на соответствующей территории. Напитки из овощей и фруктов, такие как соки, морсы, нектары, являются неотъемлемой частью ежедневного рациона человека и практически не имеют возрастных ограничений. Таким образом, первостепенная задача перерабатывающей промышленности – сделать эти продукты полезными и востребованными потребителем. Цель исследований – выделить источники высокого содержания биологически активных веществ для получения функциональных продуктов при использовании плодов местного нетрадиционного растительного сырья. В статье сделан вывод, что наибольшими показателями содержания растворимых сухих веществ отличались: черноплодная рябина – сорт Черноокая, смородина черная – сорт Зеленая Дымка и виноград темный Vitis labrusca L. – от 14,0 до 14,9 %. По содержанию витамина С наиболее высокое содержание отмечено в плодах винограда темного Vitis labrusca L. и шиповника – сорт Витаминный – 110,0–800,0 мг%. Лидерами по антиоксидантной активности стали вишня – сорт Молодежная, смородина черная – сорт Зеленая Дымка и шиповник – сорт Витаминный – 372–1450 мг%. По результатам исследований плодов и ягод садовых культур выявлено, что по основным технологическим показателям выделяются: черноплодная рябина – сорт Черноокая, шиповник – сорт Витаминный, виноград темный Vitis labrusca L., смородина черная – сорт Зеленая Дымка и вишня – сорт Молодежная.
ANALISIS DESKRIPTIF TERHADAP INOVASI LAYANAN APLIKASI SAMBARA (Samsat Mobile Jawa Barat)
Authors: Ramdani Ari
Published: February 2020

Penelitian ini berbicara terkait dengan inovasi layanan publik berupa aplikasi SAMBARA (Samsat Mobile Jawa Barat). Penelitian ini berupaya untuk menggali sejauhmana kebermamfaatan inovasi layanan tersebut dan berupaya untuk mendapatkan jawaban mengenai penyebab Badan Pendapatan Daerah (BAPENDA) Jawa Barat dapat melakukan inovasi layanan aplikasi SAMBARA ini. Penelitian ini dilakukan dengan menggunakan metode penelitian kualitatif dengan analisis deskriptif. Beberapa temuan dari penelitian ini diketahui bahwa inovasi layanan ini banyak membantu masyarakat untuk membayar pajak kendaraan bermotornya kapan saja dan dimana saja dan pada akhirnya dapat meningkatkan pendapatan pemerintah daerah provinsi Jawa Barat. Temuan lainnya adalah faktor pendukung, diantaranya adalah political will dari para pejabat, kemudian pula tidak lepas dari faktor dari pihak swasta baik itu perbankan ataupun perusahaan-perusahaan atau toko online semacam bukalapak, indomaret yang mengakomodir pembayaran pajak tahunan kendaraan bermotor, yang memudahkan masyarakat dalam mendapatkan layanan ini.
KEBIJAKAN PEMERINTAH DESA SEKAR DALAM PELESTARIAN TRADISI �CEPROTAN�
Authors: Mustaqim Muhammad Khoirul , Nugroho Krishan Yudi , Kusuma Dewi Dian Suluh
Published: February 2020

Di Indonesia memiliki banyak tradisi budaya salah satunya yaitu, tradisi Ceprotan. Tradisi ini adalah upacara bersih desa yang dilaksanakan di Desa Sekar Kecamatan Donorojo Kabupaten Pacitan. Tujuan utama dari diselenggarakannya tradisi ini yaitu keselamatan desa dan menjauhkan dari mara bahaya. Tradisi ini diselenggarakan setahun sekali, yaitu pada bulan Longkang atau Selo (DzulQa�adah / Dulkangidah) hari pasaran Senin Kliwon atau pada hari Minggu Kliwon sebelum menjelang matahari terbenam. Penelitian ini mendiskripsikan asal-usul Ceprotan dan kebijakan Pemerintah Desa Sekar dalam pelestarian tradisi Ceprotan. Penelitian ini menggunakan metode adalah deskriptif kualitatif. Dengan teknik pengambilan data dari observasi dan studi kepustakaan seperti surat kabar, majalah, dokumen dan media informasi lainnya. Dapat diambil kesimpulan bahwa kebijakan yang diambil pemerintah sangat berperan dalam pelestarian kebudayaan tradisional dan menghadapi hambatan � hambatan yang terjadi dalam proses pembangunan pariwisata.
A classical encyclopedia: basic technology and methods
Authors: Petrovskaia Lidiia
Published: February 2020

The article discusses methodological approaches and content preparation technologies used in universal encyclopedias.
Ukraine and Ukrainians on the pages of books of The Bashkir Encyclopedia Scientific Publishing Complex
Authors: Agliullina Klara , Sharapova Liana
Published: February 2020

On the pages of The Bashkir Encyclopedia Scientific Publishing Complex editions provides broad information about Ukraine and Ukrainians living in the territory of the Republic of Bashkortostan, or activities associated with the development of industry, science, culture and other spheres. Occupy a special place articles on the activities of the Academy of Sciences of the Ukrainian SSR during the evacuation on the republic during the Great Patriotic War. Moreover, the activities of scientists of the Academy of Sciences of the Ukrainian SSR, their contribution to the development of mechanical engineering, oil reVning, petrochemical and other industries, geology, physics, biochemistry and other branches of science is the subject of research of many scientists, ethnographers of the Republic of Bashkortostan.
Indexes of reproductive ability and their repeatability in sows of different genotypes, taking into account the polymorphism g.1426g> a of the Mc4r gene
Authors: Khalak Viktor , Voloshchuk Vasyl , Pochernyaev Konstiantyn , Smyslov Serhii , Ilchenko Maria
Published: February 2020

The results of studies of the reproductive ability of sows of different genotypes are given taking into account the polymorphism g.1426G> A of the MC4R gene, the factor of repeatability of characters is determined, and the economic efficiency of the research results is calculated. The experimental part of the research was carried out in the conditions of the «Druzhba-Kaznacheevka» LTD in Dnipropetrovsk region. The objects of research were sows of the Large White breed.
It was determined that sows of the main herd, according to signs of reproductive ability, belong to class I and class elite. The experiment showed that sows of genotype AG exceeded their peers of others (GG and AA) in terms of “born piglets total, heads” by 1.6 and 0.7 heads, “Live piglets born (multiple births), heads - by 1 6 and 0.9 heads, “the mass of the litter at the time of birth, kg” - by 2.7 - 1.3 kg., “the mass of the litter at the time of weaning at the age of 28-35 days, kg” - by 5, 1 - 3.9 kg. The difference between animals of the indicated genotypes is: for large-foetus - 0.06-0.01 kg, the index "evenness of the sow’s litter in live weight of piglets at birth, points" - 1.05-1.84 points, index of N. D. Berezovsky - 3.75 -2.36 points. The index of the safety of piglets before weaning ranged from 84.4 to 93.0 %. It was proved that the minimum value of the index “evenness of the sow’s littar in live weight of piglets at the time of birth, points (7.76 ± 1,082 points) are characterized by sows of genotype AA, in which the rate of multiple pregnancy ranged from 8 to 14 pigs, and the value of the sign“ large-foetus, kg "equaled 1.37 kg. The repeatability coefficient for sows of the main herd and sows of the Large White breed of different genotypes for the melanocortin 4 (MC4R) receptor gene ranges from -0.916 ± 0.1418 (І-IV farrow, genotype - GG, sign - “piglet safety before weaning, %) to 0.978 ± 0.0738 (I-V farrow, genotype - GG, sign - “large foetus”, kg ”). The maximum value of the phenotypic consolidation coefficient was found in sows of genotype AA according to the following quantitative characteristics: “live piglets (multiple births), heads.”, “litter weight at the time of birth, kg”, “litter weight at weaning age of 28-35 days, kg "," the safety of piglets before weaning ,% ".
The sows of the genotype GG belong to the unconsolidated group according to the signs of reproductive qualities. The use of sows of the genotype for the melanocortin 4 (MC4R) AG receptor gene provides additional products at the level of 5.15 %, and its cost is 165.41 UAH /head.
Keywords: sow, breed, reproductive ability, MC4R gene, genotypic consolidation coefficient, variability, correlation, repeatability.
Biochemical indexes of blood of different genotypes of pigs
Authors: Voloshchuk Vasyl , Huk Malvina
Published: February 2020

Changes in technological processes, feeding conditions, content have a great influence on the mechanism of adaptive response of pigs. Distinguish between short-term and long-term adaptation. Long-term adaptation is defined over several generations by reproductive and fattening qualities. Short-term one is studied by blood indexes (biochemical, hematological), ethology, physiological features.
There are many stressors that affect pigs, impair their reproductive capacity, digestive processes, and can lead to the death of animals. Therefore, the question now is to create animals of such genotypes, which must have high meat quality and stable homeostasis. With severe stress or constant irritation, this affects the stability of the blood composition. Blood indexes are known to reflect the internal physiological state of animals. Blood reflects hormonal and enzymatic reactions, performs protective functions of the body. That is why we have set the goal of studying the biochemical and hematological indexes of blood of pigs of different genotypes.
The study was carried out at the State Enterprise "Stepne" and the laboratories of the Institute of Pig Breeding and agro-industrial production of NAAS.
For the study we formed three groups of pigs of 5 heads: purebred the Large White (LW×LW) and local the Large White×Mirgorod (LW×M), the Large White×Mirgorod+1/ 8Pietren(LW×M+1/8P). Blood was taken from pigs in the morning before feeding with a large ear vein. The studies were performed according to conventional methods.
Pigs of the LW×M+1/8P local group were found to have high glucose content, an indicator of the effects of stress on the body. Also in this group of pigs were identified leukocytosis, which can be the result of stress.
The eosonophils and basophils were slightly underestimated in pigs of the LW×M+1/8P group, which also confirms the previous findings on the reduced stress resistance of pigs. Other indicators that are responsible for the clinical stability of the organism were within normal limits.
There was also a slight increase in total protein in pigs in the local LW×M, LW×M+1/8P pigs, which indicates accelerated metabolic processes in the body that can be caused by overfeeding.
In purebred LW×LW and local LW×M groups of pigs, all biochemical and hematological parameters of blood were within the normal range, which indicates their stress resistance.
Key words: pigs, resistance, adaptation, blood, hematological parameters, biochemical indexes.
Evaluation of haploid diversity of sows of the Large White breed of the pedigree factory of the State enterprise “Experimental enterprise “imeni 9 Sіchnja”
Authors: Hodyna Ruslan , Matiiuk Valeriia , Buslyk Tetiana , Pochernyaev Konstiantyn
Published: February 2020

The development and use of effective selection programs accelerated the genetic improvement of breeds, advances in feeding technology allowed for optimal nutrition, and the creation of identical and strictly controlled production conditions, a uniform and strictly controlled production environment led to the replacement of local pig breeds with highly productive transboundary breeds. This development of the industry has led to increased concern about the erosion of genetic resources. The number of purebred boars of the Large White breed in 1973 amounted to 98.3 % of the total number of boars of this breed, and sows - 38.9 %. These data allow us to assume that significant haploid diversity could persist in the individual pedigree factory of the Large White breed. Thus, the subject of our study was the assessment of the haploid diversity of the Large White sows of the pedigree factory of the State enterprise “Experimental enterprise “imeni 9 Sіchnja”, the Institute of Pig Breeding and AIP NAAS of Ukraine.
For the study, samples of the bristles of 25 sows of the Large White breed of the SE "Experimental enterprise "imeni 9 Sіchnja" of the Institute of Pig Breeding and AIP NAAS of Ukraine, representing all families. DNA isolation from bristles was performed using a Chelex-100 ion exchange resin. Mitochondrial haplotypes were determined using PCR-RFLP analysis according K. F. Pochernyaev (2016).
Among the sample of breeding pigs of the Large White breed of the SE “Experimental enterprise “imeni 9 Sіchnja”, mitochondrial haplotypes B1, B2, C, G, and J1 were identified. In previous studies, seven mitochondrial haplotypes were found among pigs of the Large White breed of Ukraine, which were found with different frequencies. The haplotypes G (14.1 %), J1 (13.3 %) and N (5.91 %) were found with the highest frequency; much less often - haplotypes A (0.3 %), B1 (1.9 %), C (9.2 %) and L (2.2 %). Thus, our studies have shown that the mitochondrial haplotypes B1, B2, C, G, J1 found in the sample of breeding pigs of the Large White breed of the SE «Experimental enterprise «imeni 9 Sіchnja» typical for pigs of the Large White breed of Ukraine except haplotype B2. Important for the restoration of the Mirgorod breed of pigs is the existence in the herd of pigs of the Large White breed of the SE “Experimental entewrprise“imeni 9 Sіchnja” animals having haplotype B1 inherent to Myrgorod breed. Thus, our studies have shown that in sows of the Large White breed breeding farm SE “Experimental enterprise “imeni 9 Sіchnja”, significant haploid diversity remains, which must be maintained at a high level in the future.
Key words: pigs, the Large White breed, haplotype, mitochondrial genome, PCR-RFLP.