bluuebunny/crossref_metadata_2025 huggingface dataset:
128 THE USE OF THE IRISH NATIONAL EARLY WARNING SCORE TO DOCUMENT NEW CONFUSION
Authors: Quirk L , Daunt R , O'Flynn A M
Published: February 2023

Background

The Irish National Early Warning System (INEWS) V2 has added ‘new confusion/altered mental status/delirium’ as a sign of early deterioration. It is captured as ‘C’ in ACVPU. A ‘C’ score’ should prompt concern regarding possible serious causes and requires urgent clinical review. The objective of this study is to identify the extent to which the INEWS ‘C’ score is used appropriately by healthcare professionals in an Irish hospital.

Methods

This is a cross-sectional study of inpatients over 65 years. Medical records, nursing notes and INEWS charts were reviewed for documentation of ‘new confusion’ during admission. The 4AT, which is a rapid delirium screening tool, was completed on the day of the audit for further confirmation. Descriptive statistics are presented.

Results

20 patients were included, 65% were male, mean age 80 years. 95% of patients had been inpatients for >10 days. No patients had an INEWS ‘C’ score documented in their INEWS chart during admission. ‘New confusion’ was documented in 45% of patients’ nursing notes and 15% of patients’ medical notes. Delirium screening was completed on 45% of patients. On the day of data collection, 65% of patients had a 4AT score greater or equal to 1, and 15% of patients had a score of 4.

Conclusion

Over half the patients reviewed in this study had ‘new confusion’ documented in their medical records or nursing notes during their admission, however, this was never captured on the INEWS chart. Furthermore, 65% of patients had a 4AT score greater than or equal to one on the day of the audit. This study highlights the need for ongoing training, behavioural change and a cultural shift by health care professionals and organisations to ensure adherence with INEWS ‘C’ score and related escalation protocols.
129 MAKING THE CASE FOR ENHANCED INTEGRATION BETWEEN MEMORY ASSESSMENT AND SUPPORT AND COMMUNITY PALLIATIVE CARE SERVICES IN ADVANCED DEMENTIA
Authors: Molloy U , O'Reilly S , Ryan K , Kennelly S
Published: February 2023

Background

In Ireland there are an estimated 64,000 people living with dementia. There is a growing body of evidence that a palliative approach, including access to specialist palliative care in the later stages of dementia is essential for wellbeing and the promotion of holistic, person-centred care. Yet many people living with advanced dementia have limited access to specialist palliative care services and such services often feel ill equipped to meet the unique, complex needs of this cohort.

Methods

This is a case study report of the joint working interface between Memory Assessment and Support (MASS) and Specialist Community Palliative Care (SPPCT). M was a 85 year old lady, with advanced dementia and history of lung cancer. CT Brain showed a large left parietal lobe tumour, probable metastatic lesion. Family agreed that further investigations were inappropriate and care objective was to manage her needs in her home in accordance with her previously known wishes.

Results

A joint initial visit with SCPCT and MASS was carried out which included medication review, symptom management and assessment of additional service need. Regular visits from SCPCT with support from primary care services and MASS ensured that appropriate services were in situ, symptoms were regularly assessed and treatment plan adjusted as needed. M was supported to die at home in the care of her family, as per her wishes.

Conclusion

This case illustrates the value of the partnership between MASS and SCPCT. Services that are responsive to client needs can ensure that appropriate care is given in the right place at the right time in accordance with their will and preference. This is in line with Slainte Care principles and provides an alternative pathway for end of live care for people with advanced dementia away from acute care settings.
136 ASSOCIATIONS OF FRAILTY WITH CONSECUTIVE GAIT SPEED TRAILS MEASURED BOTH WITH AND WITHOUT ADDITIONAL STRESSORS
Authors: Davis J , Knight S P , Rizzo R , Donoghue O A , Kenny R A , Romero-Ortuno R
Published: February 2023

Background

Frailty is associated with gait speed and is defined as increased vulnerability to stressors. While usual gait speed is often measured, gait speed under additional stressors such as simultaneously reciting alternate letters of the alphabet (cognitive dual task) or walking at maximum pace are also measured. Consecutive trials may introduce an additional temporal stressor and we hypothesise that frailty may be associated with a greater reduction in walking speed across trials.

Methods

Data from community-dwelling adults aged 50+ years at Wave 3 of The Irish Longitudinal Study on Ageing were utilized. Using a 32-item frailty index (FI) we derived non-frail, pre-frail and frail groups. Gait speeds were measured using a 4.88 m walkway (GAITRite, CIR Systems, NY, USA). We examined differences in gait speed between two consecutive walks in three conditions (usual pace, cognitive dual task, and maximum pace) for the entire cohort, and by frailty group. Related-samples Wilcoxon signed rank tests were employed, with statistical significance set at P < 0.05.

Results

For the entire cohort, walk 2 speed for usual and cognitive conditions was higher by 1.0 cm/s (N = 4,097) and 1.1 cm/s (N = 3,927) respectively, and lower by 1.9 cm/s for maximum (N = 3,926). Stratified by FI, all groups walked more quickly in normal (1.0, 1.1, 1.2, respectively) and cognitive (1.3, 0.8, 0.5), and more slowly in maximum (−2.2, −1.6, −1.0).

Conclusion

In our analyses, higher frailty seemed to be associated with a higher increase for the usual walk, a smaller increase for the cognitive walk, and a smaller decrease in maximum speed. The clinical significance of the differences was very small. However, our results support that in research and clinical practice, frailty by FI should not be expected to lead to a different pattern of gait speed change across consecutive trials.
138 DELAYED BLOOD PRESSURE RECOVERY AFTER STANDING INDEPENDENTLY PREDICTS FRACTURE IN COMMUNITY-DWELLING OLDER PEOPLE
Authors: Doyle K , Lavan A , Kenny R-A , Briggs R
Published: February 2023

Background

Orthostatic hypotension, characterized by delayed blood pressure recovery (DBPR) after standing, is a risk factor for falls but the longitudinal relationship with fracture is not yet known. The aim of this study was to examine the prospective risk of fracture associated with DBPR.

Methods

This study, embedded within the Irish Longitudinal Study on Ageing (TILDA), examined prospective risk of fracture (hip, wrist or vertebral) associated with DBPR at 8-year follow-up in a population-representative sample of more than 3,000 (54% female) community-dwelling older people. Orthostatic blood pressure (BP) was measured using a finometer during active stand at TILDA Wave 1. DBPR was defined as systolic BP ≤ 20 mmHg lower and/or diastolic BP ≤ 10 mmHg from baseline value at 30, 60 and 90 seconds after standing. Participants with a fracture reported at any of Waves 2–5 were defined as having ‘Incident Fracture’. Logistic regression models were used to estimate odds ratios (ORs) for the association between DBPR and incident fracture.

Results

Seven percent (212/3117) of participants sustained a fracture during follow-up. DBPR at 30 seconds was a significant predictor of any fracture [OR 1.80, 95% confidence interval (CI) 1.28–2.53] and hip fracture (OR 4.44, 95% CI 2.03–9.71) in fully adjusted models. DBPR at 30 seconds did not predict wrist or vertebral fracture. DBPR at 60 seconds also predicted any fracture (OR 1.74, 95% CI 1.19–2.54) and hip fracture (OR 4.66, 95% CI 2.12–10.26) whereas DBPR at 90 seconds predicted any (OR 1.99, 95% CI 1.38–2.87), wrist (OR 1.87, 95% CI 1.19–2.95), and hip fracture (OR 3.39, 95% CI 1.45–7.93) in fully adjusted models.

Conclusion

Delayed BP recovery independently predicts fracture in community-dwelling older people, is potentially modifiable, and can be measured in an ambulatory setting. Given the morbidity and mortality associated with fractures, identification of such risk factors is crucial in order to inform preventative strategies.
140 FAMILY DEMENTIA SUPPORT TRAINING—AN INTEGRATED CARE APPROACH
Authors: McHale C , Fallon A , Donnelly M , Dookhy J , McGuinn C , Domsa M , McNally D , Tobin F , Kennelly S
Published: February 2023

Background

There are approximately 64,000 people living with a diagnosis of dementia in Ireland. This number is expected to double to 150,000 by 2045. The growing need for post diagnostic support has been accentuated by the fact that we are living through an unprecedented Pandemic. Our Dementia Training Network identified the need for a localised educational resource for families supporting those diagnosed with dementia across our service.

Methods

Following a successful pilot in association with the Alzheimer’s Society of Ireland, staff from the Specialist Memory Service, Integrated Care Team, and Primary Care created a service-informed 6 week course aimed at supporting families. A focus group preceded the first course to establish preferred content. The course delivered education on Dementia; Post Diagnostic Steps; Communication; Non cognitive symptoms; Nutrition & hydration; Assistive Technology; Forward planning and Self-care. The multi-dimensional nature of staff delivering the course creates a rich tapestry of advice and information. All staff involved work together to identify, refer and support families living with dementia in the local area. The group takes place in an accessible location and time which accommodates families. Each course attendee completes a questionnaire prior to and after commencing the group. The level of satisfaction will be measured following every course.

Results

By the end of 2021, the group will have delivered education and support to 36 families. The automatic referral of all families to this resource will assist in building up confidence to support and enhance self-care. The combined participants from the catchment area will become a network of families joined together on their journey.

Conclusion

This innovative service collaboration enhances the integrated nature of the Post Diagnostic Care pathway. The Integrated care approach has served to enrich the programme and allow for timely support and advice regarding localised supports.
157 WHOLE HIPPOCAMPAL VOLUMES AND HIPPOCAMPAL SUBFIELD VOLUMES IN MCI-LB AND MCI-ad
Authors: Durcan R , Colloby S J , Donaghy P C , Lawley S , Taylor J-P , O'Brien J T , Thomas A J
Published: February 2023

Background

Mild cognitive impairment with Lewy bodies (MCI-LB) is the commonest prodromal phenotype of Dementia with Lewy Bodies (DLB) and may be challenging to differentiate from MCI due to Alzheimer’s disease (MCI-AD). Preservation of medial temporal lobe structures on MRI is recognised as a supportive biomarker consistent with underlying Lewy body disease rather Alzheimer’s disease (AD).

We investigated whether whole hippocampal volume and differing hippocampal subfield atrophy patterns, could be used as a surrogate biomarker of underlying ad pathology, allowing for differentiation of MCI-LB from MCI-AD.

Methods

Participants were recruited to the following groups’: healthy controls (HC), MCI-LB and MCI-ad, all ≥60 years. Alongside detailed clinical, neuropsychological assessments, all participants underwent 3 T MRI, 123I-FP-CIT SPECT and 123I-MIBG myocardial scintigraphy. Using Freesurfer (v.6.0), a fully automated hippocampal subfield segmentation of the MRI data was performed.

Results

Groups consisted of 31 HC (mean age, 73.7 yrs; mean Mini-Mental state Examination [MMSE] score, 28.4), 34 MCI-LB (mean age, 74.7 yrs; mean MMSE score, 26.6) and 29 MCI-ad (mean age, 75.4 yrs; mean MMSE score, 27.1).

There was no significant difference in whole hippocampal volume between MCI-LB and MCI-ad(Mean (SD) in mm3: MCI-LB 6025 (961) vs MCI-ad 5407 (882), p = 0.12) or between MCI-LB and HC (Mean (SD) in mm3: MCI-LB 6025 (961) vs HC 6355 (962), p = 0.11). Whole hippocampal volume was significantly smaller in MCI-ad compared with HC (p < 0.001).

Comparison between MCI-LB and MCI-ad, showed absolute hippocampal subfield volumes were all lower in MCI-ad. However, the magnitude of the differences were small and no significant difference in hippocampal subfield volumes were noted between these groups, with the exception of the hippocampal tail being significantly smaller in MCI-ad compared to MCI-LB (p = 0.04).

Conclusion

In a well-characterised cohort, whole hippocampal and hippocampal subfield volumes were similarly atrophied in MCI-LB and MCI-ad and did not distinguish between the groups.
172 ‘NCHD’S UNDERSTANDING OF THE ‘DYING WITH DIGNITY BILL”
Authors: Ahern E , McGurk C , Claffey P
Published: February 2023

Background

The Dying with Dignity Bill is potential legislation that would permit terminally ill people to avail of medical assistance to die in certain circumstances. It would give a medical practitioner the legal right to provide assistance to a qualifying person to end their life, thus changing the medical landscape as we know it. This project aimed to assess current understanding in non-consultant hospital doctors (NCHDs) of the Dying with Dignity Bill.

Methods

An online survey was distributed to NCHD’s across a range of disciplines to ascertain current knowledge of the Dying with Dignity Bill. Descriptive analysis of data was conducted on Excel.

Results

The survey was completed by 80 NCHDs. Of respondents 67.5% (n = 54) of respondents had heard of the Bill and 32.5% (n = 26) of them knew what it was. The Bill had not been read by 88% (n = 71) of respondents. Fifty seven per cent (n = 46) did not understand what was entailed in the Bill. The majority agreed (61.3%; n = 49) that it would impact their work as a clinician. Some 70.1% (n = 56) agreed that legislation was needed in this area. The majority answered neutral (45%; n = 35) that their profession were consulted in the creation of the Bill. It is believed that the Bill will not require a vote however 48% (n = 37) believed it would. However, the majority (72.7%, n = 56) answered correctly that the Bill had not been enacted yet. This Bill does not define the length of a ‘terminal illness’ yet 36.8% (n = 28) believed it to be within six months. It also states that it is the practitioner’s role to decide when somebody is palliative and only 54.5% (n = 42) knew this.

Conclusion

The Dying with Dignity Bill is poorly understood by NCHDs, despite it potentially having an impact on the role of hospital doctors in Ireland. Discussion and involvement of NCHD’s in the potential formation of this Bill is crucial.
173 SYSTEMATIC REVIEW-BASED FINDINGS TO GUIDE THE DEVELOPMENT AND REPORTING OF CONSENSUS-BASED CRITERIA FOR INAPPROPRIATE PRESCRIBING IN OLDER ADULTS
Authors: Ali A , Alshareefy F , McMahon N , Ryder S
Published: February 2023

Background

Formal consensus development methods are widely employed to develop inappropriate medication assessment criteria for older adults. However, standards for conducting and reporting these methods are lacking. This study aims to summarise findings on consensus attainment across published explicit criteria.

Methods

A systematic literature review of criteria for assessing inappropriate medications in older adults was conducted in PubMed, CINAHL, EMBASE and Scopus (1991 to 2020). Search terms pertained to the concepts of inappropriate prescribing, criteria development/validation, and older patients (aged 65 years or more). Articles were included for the current subanalysis if they represented a consensus based explicit list, assessing appropriateness of medications in older adults.

Results

From 73 tools identified in the systematic review, 58 tools (79%) had been developed and/or validated by formal consensus methods. 51 criteria sets were reported as having been developed using Delphi (n = 30) and modified Delphi (n = 21) methods. However, most (29/30) of the reported Delphi methodologies had actually been modified by introducing an initial literature-based questionnaire. The criteria for achieving consensus between experts were pre-specified for 42 criteria sets, while the remainder did not report or prespecify consensus definitions. Where available, consensus definitions varied considerably. Arbitrary levels of proximity to a central tendency (e.g. mean +/− 95% confidence interval, median +/− interquartile range) defined consensus in 22 criteria. Seven more criteria followed the RAND/UCLA consensus definition (i.e. three-point region containing the median) (1). Only one set addressed consistency of agreement between rounds. Likert scales or categories for ranking ranged from three-point to 100-point scales.

Conclusion

The development and reporting of formal consensus-based criteria varies substantially, particularly in distinguishing between Delphi methods and their modifications. This highlights the need for standards for conducting and reporting consensus attainment.

1. Fitch K, Bernstein SJ, Aguilar MD, et al. The RAND/UCLA Appropriateness Method User’s Manual: RAND Corporation, 2001.
18 SEDATIVE LOAD IN COMMUNITY-DWELLING OLDER ADULTS WITH MILD–MODERATE ALZHEIMER’S DISEASE: LONGITUDINAL RELATIONSHIPS WITH ADVERSE EVENTS, DELIRIUM AND FALLS
Authors: Dyer A , Murphy C , Lawlor B , Kennelly S
Published: February 2023

Background

Older adults are frequently prescribed medications with sedative effects, which are associated with numerous adverse consequences. However, the use and longitudinal associations of sedative medication use in older adults with mild–moderate Alzheimer Disease (AD), has not been explored to date.

Methods

The association between Sedative Load (SL) and adverse events, unscheduled healthcare utilisation, delirium and falls over 18 months was assessed in older adults with mild–moderate AD from 9 Countries. Additionally, the impact of SL on dementia progression was evaluated.

Results

Over half (52.35%; 267/510) of those with mild–moderate ad (72.8 ± 8.26 years, 61.89%) were prescribed a regular medication with sedation as a primary effect or prominent side effect with 17.65% (90/510) having a high SL (≥3). The most common medications contributing to SL were antidepressants, antipsychotics, anxiolytics and hypnotics. Over 18 months, greater SL was associated with adverse events (IRR 1.18, 1.14–1.23, p < 0.001)/serious adverse events (IRR 1.32, 1.18–1.49, p < 0.001) and unscheduled GP visits (IRR 1.26, 1.15–1.38, p < 0.001). Further, increasing SL was associated with greater likelihood of incident delirium (IRR 1.47, 1.25–1.73, p < 0.001) and falls (IRR 1.25, 1.06–1.48, p = 0.007) which persisted after covariate adjustment. SL was not associated with accelerated cognitive decline or ad progression.

Conclusion

Most adults with mild–moderate ad are prescribed at least one drug with a sedative effect and a significant minority have a high SL. Increasing SL was associated with a greater likelihood of experiencing adverse events, delirium and falls, highlighting the need for optimal prescribing in this vulnerable cohort.
180 NURSING HOMES DURING THE COVID-19 PANDEMIC: A NARRATIVE REVIEW OF CHALLENGES AND RESPONSES
Authors: Giri S , Chenn L M , Romero-Ortuno R
Published: February 2023

Background

COVID-19 has caused unprecedented challenges in nursing homes. In this narrative review, we aimed to describe factors that contributed to the spread and mortality of COVID-19 in nursing homes and provide an overview of responses that were implemented to try to overcome such challenges.

Methods

The MeSH terms ‘Nursing homes’ and ‘COVID-19’ were searched in MEDLINE Ovid, and English language articles were retrieved that were published between 1 March 2020 and 31 January 2021. Article titles and abstracts were screened by two reviewers, and the results of included articles were grouped by themes.

Results

The search retrieved 348 articles, of which 76 were included in the thematic review. 8 articles related to COVID-19 disease characteristics (e.g. asymptomatic transmission), 24 to resident-related factors (e.g. comorbidities, nutrition, cognition), 13 to facility characteristics (e.g. physical space, occupancy, for-profit status), 21 to staffing (e.g. staffing levels, staff-to-resident ratio, staff multi-employment), and 10 to external factors (e.g. availability of personal protective equipment, prevailing health and social care policies). In terms of responses, identified themes included widespread testing, isolation and cohorting of residents, staff protection and support, promotion of residents’ well-being, and technological innovations.

Conclusion

COVID-19 exerted severe challenges on the nursing home population and its staff. Both internal and external factors predisposed nursing homes to an increased propensity of spread. Numerous strategies were employed to attempt to mitigate the negative impacts. Substantial learning occurred that may not only aid future pandemic preparedness but improve quality of care for nursing home residents at all times.
187 A QUALITATIVE EXPLORATION OF PLACE AND PERSONHOOD IN DEMENTIA
Authors: Hennelly N , Walsh K , Urbaniak A , O'Shea E
Published: February 2023

Background

In dementia research, supporting personhood is seen as a corner stone of person-centred care. However, little is understood about how personhood is conceptualised in the context of the home and communities that people living with dementia reside within, and how place may constitute a key dimension of, or a determining factor of someone’s sense of self. This study seeks to explore these relationships by examining the intersection between place and personhood through the lens of Rowles (1983) work on place and personal identity in old age.

Methods

Qualitative secondary analysis of datasets from two separate studies was conducted. The first study examined the perspectives of people living with dementia on place across the life course, while the second study examined the perspectives of people living with dementia on personhood in formal care. In total, 15 interviews with people with dementia were analysed using theoretical framework analysis.

Results

Participants reflected on the meaning of place, and its iterative relationship with personhood across the life course. They used the residential life course, to convey and narrate their life story, locating themselves and major events in time and place. Participants also spoke about the impact of the physical environment on their sense of personhood, conceptualising personhood in relation to attachment to the physical landscape, location and their own homes. Finally, participants referred to the close link between place, relationships, and community. In particular, how important feelings of community and belonging to place are to their sense of personhood.

Conclusion

This research shows the role of place in interpreting understandings of personhood from the perspectives of people living with dementia. This is critical for understanding the nature and orientation of community-based interventions, and designing supports and services which appropriately harness place-based relationships of people living with dementia.
190 FACTORS ASSOCIATED WITH ADHERENCE TO COVID-19 PUBLIC HEALTH GUIDELINES AMONG OLDER ADULTS IN IRELAND
Authors: Hennelly N , Lalor G , Gibney S , Murphy R , Kenny R A , Ward M
Published: February 2023

Background

Older adults are at high risk from coronavirus 2019 (COVID-19). Even with the introduction of a widespread vaccination programme, adherence to public health guidelines continue to be of vital importance to reducing the spread of COVID-19. This study examines the factors associated with adherence to two public health guidelines, social distancing and mask wearing, among older adults (50 years and over) in Ireland.

Methods

Data from the Irish Longitudinal Study on Ageing (TILDA) COVID-19 study and previous waves of TILDA was used. The COVID-19 study data was collected between July 2020 and November 2020. Logistic regression analysis was conducted separately to examine the relationship between the independent variables and social distancing and mask wearing respectively. Along with socio-demographic variables, the Health Belief Model (HBM) was used to identify variables for inclusion in the analysis.

Results

In total, 2,816 participants were included in this study. Females were more likely than males to adhere to social distancing and mask wearing guidelines. Those most concerned about COVID-19 were more likely to adhere to both behaviours. Education levels were associated with adherence to both behaviours but the direction of the relationship differed. Those who trusted the Health Service Executive as a news source were more likely to socially distance, while those with less understanding of government guidance and those who trusted in government news sources were less likely to socially distance. Participants who were working were less likely to socially distance than those who weren’t. While, participants who were over 70 and those who returned the survey after the introduction of mandatory mask wearing were more likely to wear a mask. Participants who lived outside of Dublin were less likely to wear a mask.

Conclusion

Factors associated with adherence to public health guidelines vary according to the guideline. Differences between groups need to be considered when implementing policy around public health guidelines.
192 USING A COLLABORATIVE APPROACH TO IDENTIFY WAYS TO STRENGTHEN ENHANCED CARE PRACTICES IN A GENERAL HOSPITAL WHILE BUILDING RESEARCH CAPACITY
Authors: Daly L , White P , Harris E , Carroll A F , Murphy A
Published: February 2023

Background

The Nursing department within an acute general hospital wished to illuminate and build on positive local enhanced care practices. A collaborative research team was formed between academics in the linked higher education institution and nurses within the hospital to address this intent by building nurse-led research capacity, while addressing the practice derived research question.

Methods

A mixed methods approach was employed involving; site visits, audit of enhanced care staffing requirements, documentary and activity box analyses and use of appreciative inquiry (AI) methodology. AI is a collaborative and strengths-oriented approach supporting organisational development. It was implemented via three World Café events (www.theworldcafe.com 2021) bringing together hospital stakeholders (n = 17) with direct experience of delivering enhanced care, to consider pre-defined questions. Thematic analysis was used to analyse the resultant data. Ethical approval was obtained.

Results

Overall, the findings demonstrated a positive focus on implementing therapeutic enhanced care within the hospital in contrast to a more passive primarily observational orientation. The site visits facilitated shared learning. Thematic findings from the World Cafés identified positive care practices and enabled a multidisciplinary, inclusive approach, which facilitated pragmatic suggestions on how to plan for, and build on existing foundations of, enhanced care practice.

Conclusion

Both the study approach and outcome resulted in positive impacts. Working collaboratively supported research capacity building for hospital-based members of the research team. Using AI supported constructive and inclusive stakeholder participation in the World Cafés with a focus on good practices and ways in which they could be strengthened. One year post completion, study recommendations have led to:
194 TIA IMAGING: ARE WE FOLLOWING NICE 2020 GUIDELINES?
Authors: Egan A , Kearns J , Khalil M , O'Connor M
Published: February 2023

Background

CT brain imaging is customary in clinical practice after Transient Ischemic Attack (TIA). However, NICE (2020) guidelines recommend MRI brain with diffusion weighted and blood-sensitive sequences; to be completed on the same day as the assessment. The purpose is to detect the ischemic territory, haemorrhage, or other pathology. The aim of this audit was to assess the diagnostic radiology investigations performed on patients, over the age of sixty-five years, presenting with TIA to a university teaching hospital.

Methods

We conducted a retrospective audit of all patients coded as TIA on the Hospital Inpatient-Enquiry (HIPE) system between July 2019 to July 2020. Data on brain imaging was accessed using the National Integrated Medical Imaging System (NIMIS) system. Hospital attendance records were accessed via the Emergency Department patient database. Data was analysed using Microsoft Excel.

Results

Eighty patients had brain imaging performed (n = 38 CT brain only; n = 1 MRI only; n = 41 CT and MRI). Of these patients, only three had an MRI brain completed within twenty-four hours where thirty-nine patients had an MRI scans outside of twenty-four hours. Forty-one patients had both a CT and MRI brain imaging performed. The median time to MRI brain was three days and one and a half hours and the median time to CT brain was two hours and forty-nine minutes.

Conclusion

This audit confirms duplication of TIA brain imaging and CT as the primary imaging tool for TIA which is not in keeping with best practice (NICE, 2020). This has implications for resources, radiation exposure and patient’s length of stay. Development of dedicated ambulatory care pathways for TIA must incorporate rapid MRI access as the primary imaging modality.
209 NEURO-MEDICAL COMPLICATIONS OF STROKE—TRENDS OVER THE DECADES IN AN ACUTE STROKE UNIT
Authors: McGarvey C , Hobson H , Greene S , Cogan N , McCabe D , McCarthy A , Murphy S , O'Dowd S , Walsh R , Coughlan T , O'Neill D , Kennelly S , Mello S , Coveney S , Ryan D , Collins R
Published: February 2023

Background

Neuro-medical complications post-stroke are common and often serious [1]. We first described complications in our stroke cohort in 1998 and sought to assess whether the severity and the nature of neuro-medical complications may have changed over time due to changes in presentation and the processes of care [2].

Methods

Analysis of stroke service database, which captures all neuro-medical complications as part of its portal for the Irish National Audit of Stroke (INAS), was completed. The frequency of each of the 19 complications was expressed as the percentage of patients that developed each complication over a certain year and over 5 years. Historical comparison was made with dataset from 1998, which captured six complications.

Results

Data on 1,283 patients presenting over 5 years between 2015–2019 was collected. The median age of all patients was 71 years (Range 21–101). In all, 19 different post-stroke complications were recorded; 48% (n = 622) had post-stroke pain, while 23.85% (n = 306) had cognitive decline. Data on 100 patients from 1998 was compared for a number of common metrics including; 21.82% (n = 275) of patients developed an LRTI in the 2015–2019 cohort compared with 14%(n = 14) in the 1998 cohort (p = 0.09) while 16.29% (n = 209) of patients developed a swallow disorder compared to 21% (n = 21) in 1998 (p = 0.22).

Conclusion

There are high levels of neuro-medical complications in stroke patients. Twenty years has seen extensive investment in hyperacute stroke care yet post-acute care complications did not appear to reduce significantly between this time, albeit with low numbers. Direction of future funding may consider the full spectrum of stroke care.
212 BUILT ENVIRONMENT OF NURSING HOMES AND INFECTION CONTROL AND PANDEMIC PREPAREDNESS
Authors: Murphy E , Burke E , O'Donoghue J , Xidous D , Grey T , Kennelly S , O'Neill D
Published: February 2023

Background

The disproportionately high death rate of nursing home (NH) residents from COVID-19 in many countries, including Ireland, has focussed attention on infection prevention and control, including the built environment, in nursing homes. This has been a poorly researched topic to date, and we undertook a systematic review of evidence for architectural design measures which support infection control and pandemic preparedness.

Methods

Databases were screened for keywords related to NHs, built environment, infection prevention and control, and COVID-19; relevant papers were uploaded onto Covidence and screened for relevance. Data extracted from included articles was tabulated under 8 specific aspects of the built environment.

Results

Of 17 papers included in the final analysis, four studies found that larger nursing homes carried an increased risk of COVID-19 infection. Crowding in NHs was also a risk factor for infection, with a high crowding index associated with COVID-19 infection in five studies. Green House care homes, which are based on small clusters of domestic dwellings, fared better than traditional NHs. Two papers found an association between the location of NHs and the risk of COVID-19 infection, with urban NHs and those in areas of high prevalence being more at risk. Two papers identified internal fittings as a target for infection prevention and control. Seven papers highlighted the role of adequate ventilation in NHs in the prevention of spread of COVID-19. Only one paper described easy access to the outdoors as beneficial to infection control.

Conclusion

Residents of NHs are amongst the most vulnerable to COVID-19 infection. When designing and building NHs, the role of the built environment in controlling the spread of the virus should not be underestimated.

This research supported by Science Foundation Ireland.
214 CARE OF THE LGBT OLDER ADULT: A NARRATIVE REVIEW
Authors: O’Malley K , Waters R
Published: February 2023

Background

The number of older Irish adults who identify as Lesbian Gay Bisexual or Transgender (LGBT) is growing. Various barriers exist which can deter LGBT older adults from effectively engaging with healthcare services. These include, and are perpetuated by, heteronormative (and cis-normative) culture within the healthcare setting, and inadequate physician knowledge of LGBT healthcare needs.

Methods

The aim of this research is to enhance our awareness and understanding of the challenges experienced by LGBT adults in later life. Key electronic databases were interrogated using a considered search strategy and selected based on specific inclusion criteria.

Results

Key themes which emerged were; health disparities of LGBT older adults compared with the wider non-LGBT population; the impact of minority stress on the burden of chronic disease; the role of marginalisation/discrimination as a barrier to engagement with health services; institutional erasure of sexuality, particularly in the setting of long term care; the importance of non-biological chosen family, particularly in the context of advance care planning and preparation for end of life; heteronormativity, cis-normativity and physician bias in the healthcare setting.

Conclusion

It is imperative for physicians and allied health professionals to familiarise themselves with the many barriers faced by LGBT older adults when interacting with healthcare services, as well as their unique concerns in later life. In doing so, we can ensure the provision of inclusive and culturally-competent care for all LGBT older adults in Ireland, enabling them to age well in a health system that is sensitive to their needs.
217 DO THE FRAIL EXPERIENCE ADVERSE EVENTS FROM INTENSIVE BLOOD PRESSURE CONTROL? FINDINGS FROM THE IRISH LONGITUDINAL STUDY ON AGEING(TILDA)
Authors: O'Donoghue P , Romero-Ortuno R , O'Halloran A , Kenny R A
Published: February 2023

Background

The 2018 ESC/ESH guidelines for the management of arterial hypertension in adults aged ≥65 years recommend a blood pressure (BP) treatment target of 130–139/70–79 mmHg if tolerated. Randomised controlled trials have recommended lower BP. However, low BP may cause adverse outcomes, especially in the frail.We aimed to identify if older adults, frail and non-frail, in wave 1 of TILDA being treated intensely for hypertension experienced more adverse events by wave 2.

Methods

Data from participants aged ≥65 years treated for hypertension in Wave 1 was analysed.Frail/non-frail was identified by Frailty Phenotype (FP) and the Clinical Frailty Scale (CFS).Two blood pressure thresholds defined intensive control:<130/70 and < 110/70 mmHg.We formulated 16 baseline participant groups based on frailty-BP combinations.Outcomes at wave 2 were analysed with adjusted binary logistic regression models.

Results

1,920 participants at Wave 1 were aged ≥65 years and treated for hypertension. 1,229 participants had full BP/FP data, while 1,288 had complete BP/CFS data.The frail by FP with treated BP >130/70 or > 110/70 had a statistically significant risk of new TIA or stroke by Wave 2.The frail by CFS with treated BP >130/70 or > 110/70 had a statistically increased risk of recurrent falls and/or fractures, as did the frail by FP with treated BP >110/70. FP with treated BP <130/70 was associated with new heart failure. None of the frail-BP groups was independently predictive of cognitive decline,myocardial infarction, syncope or hospitalization. For the non-frail-BP groups,there was no increased risk of any of the outcomes.

Conclusion

Frail older adults treated to higher BP thresholds seemed to have more adverse short-term health outcomes compared to the frail treated more intensely. Overall, a BP of <130/70 did not seem associated with more adverse outcomes. This 2-year prospective study’s results of a community-dwelling cohort may not be generalisable to clinical populations.
221 PREVALENCE AND DOCUMENTATION OF DELIRIUM IN A UNIVERSITY HOSPITAL
Authors: Kajawo S , Flynn D , Buckley M
Published: February 2023

Background

Delirium can complicate approximately 10% of all medical admissions and prevalence increases in those with cognitive impairment, increasing age and medical complexity. Delirium is associated with increased morbidity and mortality as well as increased length of stay. Prompt recognition and treatment is essential. The National Delirium Care Bundle suggests assessment and recognition at the earliest opportunity and documentation of delirium if patients screen positive.

Methods

We carried out an audit among patients admitted in all medical wards to identify delirium and assess if it was documented and a care bundle opened. All patients were screened using the 4AT tool at least once over the space of one week. Medical notes were also screened to assess for documentation of delirium.

Results

95 patients were screened and 32 (33%) of these screened positive. Of these only 11 patients had a diagnosis of delirium documented in medical/nursing notes and a delirium care bundle opened. 50% of CCU patients were delirious. The Geriatric Medicine Ward had a lower prevalence of 19% with 66% identified in medical notes.

Conclusion

These results are disappointing with only 34% of patients identified as having a delirium. This audit is part of a quality improvement project with education sessions ongoing and roll out of the national delirium/dementia pathways across the medical wards. We hope to present our interventions and completed audit loop shortly.
233 BISPHOSPHONATES: ANOTHER COMPLEX DRUG TO PRESCRIBE
Authors: Mustafa W , O'Byrne R , Okpaje B , Gabr A , Ali B , Mohamed A , Cameron S , Leahy A , Fernandes L , Mannion M , Ryan P , Ryan S , Peters C , Shanahan E , Galvin R , O'Connor M
Published: February 2023

Background

Bisphosphonates provide effective treatment for osteoporosis. They accumulate a bone reservoir lasting for 3 years and beyond. The 2021 NICE guidelines recommend a medication review and a ‘drug holiday’ after 5 years of oral bisphosphonate therapy for low-fracture risk patients. Continuing treatment for high risk individuals is advised: age=/>75, previous hip or vertebral fracture, one or more fractures during treatment, recent DEXA scan with T score =/<−2.5, and/or current treatment with oral glucocorticoids. This retrospective audit aimed to assess compliance with NICE guidelines in a primary care setting.

Methods

Data were collected using the Health One online medical record system in an urban general practice. Inclusion criteria: all patients =/> 65 years old, prescribed oral bisphosphonate therapy for osteoporosis for >5 years. Exclusion criteria: deceased, did not attend clinic >1 year, patients on bisphosphonate treatment for conditions other than osteoporosis.

Results

137 patients with a history of bisphosphonate therapy were identified. 76 patients were on bisphosphonate treatment for greater than 5 years. Of the 76 patients, 33 were classified as low-fracture risk and appropriately commenced a drug holiday, while 22 correctly remained on bisphosphonates due to a high fracture risk. The remaining 21 patients inappropriately continued therapy without receiving a medication review, repeat DEXA or fracture-risk assessment.

Conclusion

One third of patients on bisphosphonates beyond 5 years were not assessed for a drug holiday. The aim of a bisphosphonate ‘drug holiday’ is to reduce poly-pharmacy and prevent rare but serious long-term adverse events (such as atypical fractures, osteonecrosis of the jaw, gastric cancer and atrial fibrillation). Factors which had an impact on inappropriate prescribing should be assessed. Incorporating computer-based prescribing alerts could support safe prescribing practices.
24 EXPERIENCES OF EARLY SUPPORTED DISCHARGE SERVICES FOLLOWING A STROKE: A QUALITATIVE EVIDENCE SYNTHESIS
Authors: Connor E O , Dolan E , Horgan F , Robinson K , Galvin R
Published: February 2023

Background

Early supported discharge (ESD) facilitates people with a stroke to be discharged from the hospital environment earlier than conventional care to continue their rehabilitation within the home with a multi-disciplinary team. From Randomised Controlled Trials, benefits of ESD include reducing long term dependency, the length of hospital stay and cost savings. This systematic review and qualitative synthesis explores the experiences of those involved in ESD including people with stroke, family members, caregivers as well as the healthcare professionals.

Methods

A literature search was completed in 11 databases which generated 3,425 articles. Qualitative or mixed methods studies that included qualitative data on the experiences of people with stroke, family members, caregivers and healthcare professionals of an ESD service were included. Methodological quality was appraised using the Critical Appraisal Skills Programme checklist. Findings were synthesised using thematic synthesis.

Results

A total of fourteen studies were identified. The methodological quality of the studies was good overall. Four key themes emerged: 1) ESD is experienced by people with stroke as a goal-focused and supportive process leading to positive outcomes, 2) ESD eases the transition from the hospital to the home environment but the transition from ESD to social and community services is often problematic, 3) Organisational, logistical and inter-professional factors are critical to the success of ESD and 4) The home environment enhances rehabilitation.

Conclusion

Our findings highlight the importance of home in the rehabilitation process post stroke. Key practice implications point to the need for increased attention to periods where care transitions occur.
246 IMPROVING LUMBAR PUNCTURE TECHNIQUE AMONG INTERN TRAINEES TO ENHANCE QUALITY OF CARE FOR PATIENTS
Authors: Antonenko A , Shanahan E , Slattery N , Leahy A , Gabr A , Condon J , Ahern E , O'Connor M
Published: February 2023

Background

Lumbar puncture (LP) is a common procedure performed on older adults in acute medical settings. A higher peri-procedural risk has been shown in older patients. Non-consultant doctors (NCHDs) often lack confidence and competence in performing LP. Simulation based training using task trainers has been shown to improve confidence, preplanning skills and technique.

Methods

A simulation based teaching session was developed in a university teaching hospital (training structure was adapted from the LP training guide published in MedEdPortal). Small group teaching (with 6–8 learners) was delivered to 25 NCHDs with no prior exposure or experience with lumbar puncture completion. Trainees completed one LP simulation without practice to mastery level. On-demand and post-performance feedback was delivered to learners. An assessment checklist was completed by the supervisor. Learners completed an anonymised quantitative and qualitative questionnaire using Qualtrics XM software at a later date to evaluate self-perceived teaching outcomes.

Results

16 doctors completed the questionnaire (64% response rate). 55% rated the LP workshop as a ‘strongly positive’ impact on their learning, while 18% indicated a ‘positive’ impact on a 5-point Likert scale. 19% of trainees reported they were ‘very comfortable’ at performing the procedure post training, with 56.5% ‘comfortable’ to perform an LP in their clinical practice. Qualitative learner feedback included ‘more hands on practice’ on the mannequin, ‘smaller groups for the workshops’ and ‘more practice tips’ during the simulation workshop.

Conclusion

This pilot study demonstrated interest and positive feedback for the LP simulation training from novice doctors with improved self-assessed confidence. Formal development of an LP simulation training curriculum is underway. The impact of this training on patient care should be assessed in practice.
249 A SURVEY OF IRISH DOCTORS VIEWS ON FLEXIBLE TRAINING
Authors: Loughlin E , McNamara R , Antonenko A , O'Regan A , O'Connor M
Published: February 2023

Background

We aimed to establish the views of non consultant hospital doctors working in Ireland on the options available for ‘Flexible Training’ or ‘Less-Than-Full-Time-Training’. Our population is ageing rapidly, and an expanding workforce will be required. Difficulties with doctor retention and recruitment are growing challenges in Ireland.

Methods

An anonymised survey of 9 questions was carried out using Survey Monkey®. Question format included multiple choice, yes/no or a free text box. This was disseminated via the Royal College of Physicians of Ireland to 1,557 trainees of the Institute of Medicine, the national postgraduate body for medical specialties. It was also circulated to members of the Irish Medical Organisation, the national medical organisation, and to approximately 200 doctors across two hospitals on social media.

Results

There were 674 (84.3%) respondents in training- 46.3% BST, 53.7% HST; and 125 (15.6%) non-training respondents. Doctors overwhelmingly felt trainees should have access to flexible training (n = 849, 99.41%), with 82.39% reporting they would apply (n = 702). Most (92.5%) felt that 16 WTE positions was inadequate (n = 789). Reasons chosen for not applying for flexible training included- 36.1% (n = 169) felt it could impact their career, 25.4% (n = 119) identified they did not meet the criteria, 14.32% (n = 67) reported no interest, while 24.1% (n = 113) gave ‘other’ reasons including lengthy training, salary impacts, and not having a requirement for flexible training. When asked about suggestions for improving flexible training, 19.7% chose ‘offer more places’, 6.7%-‘remove eligibility criteria’, 19.6% -‘offer job sharing options’, 9.5%- ‘allow more flexible training years’, 17.7% -‘regional based training’, 22.5% -‘all of the above’, 4.9%—‘other’.

Conclusion

Our survey suggests non consultant hospital doctors in Ireland strongly desire an expansion of current flexible training options. This is essential to ensure Ireland is an attractive place for doctors to work, to support their health and wellbeing, and to ensure an adequate workforce to care for an ageing population.