bluuebunny/crossref_metadata_2025 huggingface dataset:
Actividades de capacitación docente en Física utilizando un automóvil
Authors: Cyrulies Ernesto E
Published: May 2017

Se muestran una serie de actividades realizadas en un curso de capacitación para docentes de Física, las que se desarrollaron a partir del uso de un automóvil como recurso didáctico. El curso consistió en una propuesta de trabajo cooperativo en la cual las actividades incluyeron mediciones reales tanto con el vehículo en reposo como en movimiento en diferentes situaciones. Se planteó como un ejemplo que permite contextualizar la Física, registrar datos y el posterior uso de modelos físicos. Por otro lado, las actividades propuestas requirieron la discusión sobre los métodos experimentales necesarios y sobre la validez de los modelos utilizados. Se espera que el trabajo sea inspirador para los docentes participantes, de modo que colabore al planteo de actividades más movilizadoras en la enseñanza de la Física.
The Characteristics of an Abstract System for the Transfer of Property in South African Law as Distinguished from a Causal System
Authors: Schutte PJW (Flip)
Published: May 2017

Two divergent systems are usually differentiated between when it comes to the way in which real rights are transferred from one person to another, namely abstract and causal systems. In this article the features of each system, the respect in which they differ from each other, and the practical implications of the distinction are established. It appears that in a causal system real rights are transferred by conclusion of the obligatory agreement, which should be valid and enforceable. The mutual intention to transfer and to receive real rights is not construed as an independent real agreement as it is contained in the obligatory agreement. In a causal system the transferor finds himself in a favourable position in relation to other parties while bona fide third parties undoubtedly get the worst of the deal since they have no protection against the disadvantageous consequences of delivery owing to a void obligation. In an abstract system the obligatory agreement is not sufficient for the transfer of real rights, the thing should also be delivered and there should be a valid real agreement which consists merely of the mutual intention to transfer and to receive real rights. The real agreement is a characteristic of an abstract system which distinguishes it from a causal system. Compared with the position of those in the causal system, the transferee and third parties find themselves in a favourable position vis-à-vis the transferor. In a causal system the concept iusta causa refers to a valid and enforceable obligatory agreement or other juridical fact which obliges the transferee to deliver the thing. In an abstract system it serves no purpose to describe the causa with reference to the obligatory agreement, since it is not a substantive law requirement for the transfer of real rights. The causa concept refers rather to the mutual intention to transfer and to receive real rights, which is nothing less than the real agreement. Since the causa is contained in the real agreement it is no longer of any use in an abstract system and should be abandoned. The Dutch system displays the characteristics of an abstract system in that a separate act of delivery should exist and a valid real agreement is a requirement for the transfer of real rights. On the other hand it also displays characteristics of a causal system, since a valid obligatory agreement is a requirement for the transfer of real rights.
FDI Inflows to Telecom Sector of India: A Critique
Authors: Iqbal Badar Alam , Turay Abdul M.
Published: May 2017

India has been progressively liberalising its FDI regime to attract foreign investment which can fill the gap between the actual and desired level of investment in the country. Despite its policy measures, India has received far less share of FDI inflows in global FDI inflows. This needs to be improved so as to effectively implement the “Make in India” campaign of the present Government. Though last few years have shown an increase in FDI inflows, still a lot needs to be done for attracting more FDI Inflows. Apart from looking at the general trends, this paper specifically examines the trends in the telecom sector of India. We find that telecom sector has its own specific trends which do not relate to the general trend of FDI Inflows. The trend has been decreasing since 2009-10 but has revived in 2014-15. As telecom sector is a major driver of Indian industry, it is imperative for the government to provide continued policy impetus to this sector so as to attract substantial FDI flows in this sector.
Revealed Comparative Advantage and Trade Specialisation: The Case of India
Authors: Bedi Priyanka
Published: May 2017

The law of comparative advantage forms the basis of international trade, which has been the backbone of the commercial world for long. In a bid to open up the economy and integrate it with the world economy, India has been undertaking a series of economic reforms since 1991, including trade reforms. In this light, this paper attempts to identify the sectors/commodities where India holds comparative advantage. The study also attempts to map the technological structure of India‟s exports, and also analyse the structural changes in the pattern of trade specialisation. The study has been conducted using data relating to exports of all 97 commodities of the Harmonized System (HS-1992) classification for three periods namely average over 1996-98, 2003-05 and 2011-13. The study found that India holds comparative advantage in a variety of products. However, an overall deterioration in India‟s RCA indices over the three periods was also found. The examination of the structural changes in the Revealed Comparative Advantage to find out whether the initial pattern of trade specialisation has strengthened or weakened revealed that India is in the stage of de-specialisation. So, there is a need for India to take steps in order to strengthen its comparative advantage.
Entrepreneurial Opportunities for Persons with Disabilities
Authors: R. Bhuvaneswari , Natarajan P.
Published: May 2017

Promoting entrepreneurship at the grass root level is the need of the hour, especially for the people who are so far excluded in the growth process, i.e., person with disabilities (PWDs). Basically disabled persons have been found to have an inherent quality of strong determination and the will power to withstand challenges. However, sometimes environmental aspects are not motivating or facilitating them in a proper perspective. In the case of South India, while government’s pro-entrepreneurship policies, together with private sector interventions are having an impact, yet disabled persons in rural and remote south India are still constrained by societal prejudices, financial limitations, and limited entrepreneurship educational opportunities. The purpose of this study is to explore the entrepreneurial opportunities for PWDs. As such, the study addresses an important literature gap concerning differently abled entrepreneurship. This paper focuses on the role of NHFDC and Ministry of Social Justice and Empowerment in promoting entrepreneurship among different abled persons.
Rural Credit Co-operatives: Significance, Challenges and the Road Ahead
Authors: Sury M. M.
Published: May 2017

Rural co-operatives form an integral part of the rural credit system in India. They are the main source of institutional credit to the farmers, and are chiefly responsible for breaking the monopoly of moneylenders in providing credit to the agriculturists. Despite the phenomenal outreach and volume of operations, the financial health of a very large proportion of rural credit co-operatives has deteriorated significantly. The institutions are beset with problems like low resource base, high dependence on external sources of funding, excessive governmental control, dual control, huge accumulated losses, imbalances, poor business diversification, low recovery etc. These institutions do not, therefore, inspire confidence among their existing and potential members, depositors, borrowers and lenders. Thus, there is a need to find ways for strengthening the co-operative movement and making it a well-managed and vibrant medium to serve the credit needs of rural India, especially the small and marginal farmers.
Diagnosis and treatment of chronic pulmonary aspergillosis: clinical guidelines of European Society for Clinical Microbiology and Infectious Diseases and European Respiratory Society
Authors: Denning, D. W. , Cadranel J. , Beigelman-Aubry C. , Ader F. , Chakrabarti A. , Blot S. , Ullmann A. J. , Dimopoulos G.
Published: May 2017

Chronic pulmonary aspergillosis (CPA) is infrequent respiratory disease which is difficult for diagnosis and can complicate other respiratory diseases and conditions. Currently, there are about 240,000 CPA patients in Europe. The most prevalent variant of CPA is chronic cavitary pulmonary aspergillosis (CCPA) which could progress to chronic fibrosing pulmonary aspergillosis (CFPA) when is untreated. Aspergillus nodules and single aspergilloma are less frequent clinical variants of this disease. All clinical variants of aspergillosis could be found in nonimmunocompromised patients with different underlying pulmonary disorders. Subacute invasive pulmonary aspergillosis, which was referred to as chronic necrotising pulmonary aspergillosis, is the most rapidly progressive clinical variant of the infection (< 3 months); it is typically diagnosed in moderately immunocompromised patients and should be treated as invasive aspergillosis. Diagnosis and management of CPA patients were previously described in sporadic guidelines. Due to this, expert group have been convened to develop clinical, radiological and microbiological guidelines. Diagnosis of CPA requires a combination of the following criteria existing for 3 months or more: one or more cavities in the lungs with or without fungal mass inside or nodules found on radiological examination; direct evidence of Aspergillus infection (using microscopic examination or biopsy culturing) or immunological response to Aspergillus spp. and exclusion of alternative diseases. Antibodies against Aspergillus spp. (precipitins) are increased in > 90% of patients. Aspergilloma should be resected if technically possible; videoassisted thoracic surgery is preferable. Chronic cavitary pulmonary aspergillosis requires longterm oral antifungal therapy to improve the patients' health and respiratory symptoms, to arrest haemoptysis and prevent the disease progression. Azole serum concentration and drug interaction should be thoroughly monitored to avoid toxic effects. Haemoptysis could be arrested using therapy with tranexamic acid or bronchial artery embolization; surgical resection of the lung is rarely required. Haemoptysis could indicate therapeutic failure and / or resistance to antifungals. Patients with a single Aspergillus nodule need antifungal therapy only if surgical resection is impossible. Antifungal therapy could be beneficial in patients with multiple Aspergillusis nodules; these patients need careful followup.
Clinical, functional and laboratory features of asthma–COPD overlap syndrome
Authors: Chubarova S. V. , Sobko E. A. , Demko I. V. , Ishchenko O. P. , Kraposhina A. Yu. , Solov'eva I. A. , Gordeeva N. V. , Salmina A. B.
Published: May 2017

The purpose of this study was to investigate clinical, functional and laboratory features of the ACOS syndrome (asthmaCOPD overlap syndrome).

Methods. We examined 108 patients: 54 patients with ACOS syndrome and 54 patients with severe asthma.

Results. The ACOS syndrome was characterized by severe course, lower lung function and pulmonary hyperinflation. A high level of systemic inflammatory markers (IL6, TNFα, CRP) was registered in both the groups. An increased neutrophil elastase blood plasma concentration was revealed in patients with the ACOS syndrome that could indicate a role of neutrophils in the inflammation. sCD31/SPECAM1 and CD38 on blood lymphocytes were higher in the ACOS group compared to the asthma group; this could be related to cellular and molecular mechanisms of endothelial dysfunction.

Conclusion: The current knowledge on the ACOS syndrome is insufficient. Clinical course and pathogenesis of this disease require further investigation.
Isolated decrease of the lung diffusing capacity in patients with systemic sclerosis without pulmonary arterial hypertension: a long-term prospective study
Authors: Koneva O. A. , Ovsyannikova O. B. , Starovoytova M. N. , Desinova O. V. , Smirnov A. V. , Alekperov R. T. , Anan'eva L. P.
Published: May 2017

The objective of this 5year prospective study was to investigate a clinical role of isolated decrease of DLCO in patients with systemic sclerosis (SS) without pulmonary arterial hypertension (PAH).

Methods. We selected 48 out of 142 patients with SS: 35 (73%) with limited SS and 13 (27%) with diffuse SS. The average length of the disease was 12.9 ± 7.9 years. Inclusion criteria were DLCO < 80% pred., forced vital capacity (FVC) ≥ 80% pred. and systolic pulmonary artery pressure (PAP) ≤ 35 mm Hg according to echocardiographic examination (echoCG). High resolution computed tomography (HRCT), spirometry, DLCO measurement, and echoCG were obtained at baseline and after 4.7 ± 1 year of follow up. All patients were treated with standard therapy.

Results. CT signs of interstitial lung disease (ILD) were found in 43 (89.6%) patients at baseline and newly developed in 3 other patients during the followup. During the followup, lung CT improved in 5 (10.4%) patients and progressed in 15 (31.3%) patients. Over 5 years, FVC did not change significantly (97.6 ± 10.7% and 100.8 ± 18.9%; р = 0.15), while DLCO significantly decreased both in limited and diffuse SS groups (59.8 ± 13.5% and 56.3 ± 12%; р = 0.006). Mean PAP values remained within normal range in majority of patients. Clinically significant FVC reduction (≥ 10%) was found in 5 patients; of them, CT signs of ILD at baseline were seen in 3 patients and newly developed during the followup in 2 others. Clinically significant DLCO reduction (≥ 10%) was documented in 11 (23%) patients, all had CT signs of ILD at baseline, although CT progression during the followup was noted only in six of them. Contemporary deterioration in FVC, DLCO and CT was found in 3 patients.

Conclusion. Clinical course of ILD in SS patients with isolated DLCO reduction and without PAH was relatively benign, with respiratory volumes being preserved within normal range for long time. Comparison of radiological and functional changes in a prospective study has suggested that DLCO is a more sensitive tool to determine ILD progression compared to HRCT. Regular DLCO measurements could be used as a reliable tool for monitoring of ILD associated with SS.
Chronic obstructive pulmonary disease in HIV;infected individuals serving sentence in the institutions of the Federal Penitentiary Service of Kirov region
Authors: Borovitskiy V. S. , Ovchinnikova E. V. , Khalyavina A. A. , Tyul'kin S. A. , Igonina O. P.
Published: May 2017

The aim of this study was to diagnose and to describe chronic obstructive pulmonary disease (COPD) in HIVinfected persons serving sentence in the institutions of the Federal Penitentiary Service (FPS) of Kirov region.

Methods. This was a crosssectional nonrandomised singlecenter study involving 30 HIVpositive hospitalised patients in a FPS medical institution. Clinical examination, chest Xray, MRC scale, CATtest, Fagerström test, CCQ questionnaire, and lung function tests were used in all patients.

Results. Almost a half of patients (16 of 30) had FEV1 / FVC < 70%. Those patients with were more likely to have COPD according to COPD questionnaire.

Conclusions. COPD is underdiagnosed in penitentiary medical institutions. Clinical findings are not sufficient to support this diagnosis. If spirometry is not available, COPD questionnaire could be useful to screening for COPD.
Pulmonary hypertension in sarcoidosis
Authors: Avdeev S. N.
Published: May 2017

Pulmonary hypertension (PH) is a relatively common complication of sarcoidosis. In different studies, prevalence of PH in sarcoidosis varies from 6% to 74%. PH associated with sarcoidosis (PHAS) is typically associated with poor prognosis. Though PHAS is diagnosed more often in patients with advanced sarcoidosis, it could occasionally occur without pulmonary parenchymal lesions. Pathophysiology of PHAS is quite complex and includes several mechanisms including pulmonary fibrosis, hypoxic vasoconstriction, pulmonary vascular granulomatous obliteration and / or angiitis, extrinsic pulmonary vascular compression, pulmonary venoocclusive disease, and left heart disease. Management of PHAS is based on treatment of hypoxemia, active sarcoidosis and comorbidities. A role of systemic steroids in therapy of PHAS remains controversial. Pulmonary arterial hypertension (PAH) specific therapy has not been yet recommended in PHAS, but prostanoids, endothelin receptor antagonists and phosphodi esterase5 inhibitors were effective in some patients with PHAS in several small trials. Additional welldesigned randomized placebocontrolled studies are needed to investigate a role of PAHspecific therapy in certain cohorts of patients with PHAS.
Molecular mechanisms of corticosteroid resistance in patients with chronic obstructive pulmonary disease
Authors: Kadushkin A. G. , Taganovich A. D.
Published: May 2017

Glucocorticoids are widely used for the treatment of chronic obstructive pulmonary disease (COPD) because of their antiinflammatory properties. However, their therapeutic effectiveness is significantly limited in COPD. Molecular mechanisms of steroid resistance include defective glucocorticoid receptor (GR) binding and translocation into the nucleus, increased expression of GRβ isoform, elevated expression of macrophage migration inhibitory factor (MIF), decreased expression of mitogenactivated protein kinase phosphatase 1 (MKP1) and histone deacetylase 2 (HDAC2). HDAC2 is involved in suppression of inflammatory genes by glucocorticoids, and its reduced activity and expression are the result of oxidative and nitrative stress induced by cigarette smoke. Oxidative stress causes activation of phosphoinositide3kinase δ (PI3Kδ) which leads to phosphorylation (activation) of Akt kinase, phosphorylation (inhibition) of glycogen synthase kinase 3β and phosphorylation (inactivation) of HDAC2. Understanding of the mechanisms leading to steroid resistance allowed identification drugs targeting this condition. Antidepressant nortriptyline and macrolide solithromycin reverse corticosteroid resistance through inhibition of Akt phosphorylation. Combination of glucocorticoid and longacting β2agonist increases GR nuclear translocation and inhibits Akt phosphorylation. The phosphodiesterase 4 inhibitor roflumilast in combination with dexamethasone improves steroid responsiveness through modulation of PI3Kδ, HDAC2, MKP1, MIF and GRβ expression. Investigation of the molecular mechanisms of steroid resistance can increase antiinflammatory properties of steroids and lead to more effective COPD treatment.
Natal'ya E. Chernekhovskaya. To the 70th anniversary
Authors: Article Editorial
Published: May 2017

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New opportunities for prevention of exacerbations of chronic obstructive pulmonary disease. Russian Respiratory Society Expert Opinion
Authors: Avdeev S. N. , Aisanov Z. R. , Belevskiy A. S. , Vizel' A. A. , Zyryanov S. K. , Ignatova G. L. , Knyazheskaya N. P. , Leshchenko I. V. , Ovcharenko S. I. , Sinopal'nikov A. I. , Stepanyan I. E. , Trofimov V. I.
Published: May 2017

Combination therapy with long-acting β2-agonists (LABA) and long-acting muscarinic antagonists (LAMA) can reduce symptoms of chronic obstructive pulmonary disease (COPD) and the risk of future exacerbations. To date, the only fixed combination of long-acting bronchodilators, indacaterol/glycopyrronium, has demonstrated a significant reduction in dyspnea and in the risk of moderate and severe exacerbations of COPD in clinical trials when compared with the combination of salmeterol/fluticasone. Addition of inhaled steroids (ICS) to long-acting bronchodilators is recommended for patients with recurrent COPD exacerbations, especially in those with asthma-COPD overlap syndrome or history of elevated blood or sputum eosinophil levels. It is recommended to consider phenotype-specific therapy including roflumilast, N-acetylcysteine, and macrolides, in patients who continue to exacerbate despite being treated with LABA/LAMA or LABA/LAMA/ICS combinations. Withdrawal of inhaled corticosteroids is possible in patients with the low risk of exacerbation and in those with severe adverse events during ICS treatment. ICS should be withdrawn in a single step in patients with no repeated exacerbations during 12 months and with moderate bronchial obstruction (FEV1 ≥ 50% predicted). Stepwise withdrawal of ICS during 3 month with continuous dual bronchodilator therapy is recommended in COPD patients with severe bronchial obstruction (FEV1 ˂ 50% predicted) without frequent exacerbations in the previous year.
A role of budesonide/formoterol fixed combination in the treatment of stable chronic obstructive pulmonary disease. A conclusion of the Expert Council of the Volga Federal district of Russia
Authors: Ovcharenko S. I. , Vizel' A. A. , Gamova I. V. , Dobrotina I. S. , Zagidullin Sh. Z. , Kupaev V. I. , Nedashkovskaya N. G. , Postnikova L. B. , Ukhanova O. P. , Fassakhov R. S. , Khamitov R. F.
Published: May 2017

Late diagnosis of chronic obstructive pulmonary disease (COPD) at advanced stage, high risk of exacerbations, low compliance of patients, and adverse effects of treatment have been still unresolved problems in the treatment of COPD despite the development of new drugs. The personalized medicine rneeds distinct indications and predictors of efficacy and safety of treatment. Budesonide/formoterol fixed combination is recommended for patients with asthma – COPD overlap syndrome and bronchitis phenotype, blood eosinophilia > 300 cells/mm3, if other causes were excluded, post-bronchodilator forced expiratory volume in 1 second (FEV1) < 50% pred.; and ≥ 2 exacerbations or ≥ 1 hospitalization related to exacerbation during the previous year. Budesonide/formoterol fixed combination is not recommended for regular use in patients with emphysema phenotype of COPD and rare exacerbations (< 2 exacerbations and without hospitalizations in the previous year).
A role of endothelial dysfunction for development of microcirculation and cardiopulmonary blood flow abnormalities in patients with COPD and different alpha-1-antitrypsin phenotypes
Authors: Titova O. N. , Kuzubova N. A. , Zolotnitskaya V. P. , Surkova E. A. , Pervakova M. Yu. , Volchkov V. A.
Published: May 2017

The aim of this study was to investigate structural and functional changes of pulmonary vessels and cardiopulmonary blood flow in COPD patients with different alpha-1-antitrypsin (A1AT) phenotypes and endothelial dysfunction. Methods. Patients with COPD stage 2 to 3 (n = 113) with different A1AT phenotypes underwent clinical and radiological examination; endothelial dysfunction markers were measured. Results. More severe COPD was associated with more severe pulmonary microcirculation disorders and more significant perfusion defects. Patients with ZZ phenotype had worse pulmonary blood flow abnormalities compared to patients with MM phenotype. Pulmonary blood flow abnormalities were closely related to endothelial dysfunction (r = 0.75) and were more significant than structural abnormalities diagnosed on multi spiral computed tomography. Severe disorders of pulmonary blood flow were not accompanied by severe pulmonary hypertension. Conclusions: Blood levels of main endothelial dysfunction markers were directly related to COPD severity. Angiotensin-converting enzyme concentration was significantly below the normal level and was related to pulmonary artery pressure. The pulmonary blood flow differed in patients with different A1AT phenotypes and COPD stage 3 or higher. Perfusion defects were more severe in patients with ZZ phenotype.
Early eradication of Pseudomonas aeruginosa infection in cystic fibrosis
Authors: Kashirskaya N. Yu. , Amelina E. L. , Krasovskiy S. A.
Published: May 2017

Severe pulmonary disease in patients with cystic fibrosis (CF) is defined by the airway Pseudomonas aeruginosa infection. P.aeruginosa has still being the leading pathogen which causes progressive respiratory disease and poor prognosis in CF. Adequate and timely treatment of the initial Pseudomonas acquisition could prevent transformation to the chronic infection. This review was aimed at descripting the current antibacterial regimens for early eradication in cases of the initial and recurrent P.aeruginosa acquisition and at discussing factors affecting the treatment efficacy. The early eradication of P.aeruginosa is necessary and extremely important in CF patients. The aggressive pharmacological therapy together with early detection and subsequent microbiological control plays the leading role for the early eradication. The first-line therapy after the initial pathogen acquisition is inhaled tobramycin.
Bronchial asthma, wheezing, flatter: probable relationships
Authors: Abrosimov V. N.
Published: May 2017

Wheezing is the most common clinical sign and one of the key diagnostic criteria of asthma. Pathophysiology of wheezing is not fully recognized. A theory of hemodynamic flatter is widely adopted. Effects of vibration are actively investigated in patients with snore and obstructive sleep apnea. Vibration can contribute to the upper airway inflammation and endothelial dysfunction in snoring patients. Therefore, the flatter (vibration) effect could be the key mechanism of wheezing in asthma patients and could promote similar changes in the lower airway microvasculature. Recently, CPAP therapy has been shown to reduce asthma symptoms and bronchial hyperresponsiveness and acts as a mechanical bronchodilator is patients with asthma without sleepassociated breathing disorders.
A review of Petr M. Kotlyarov' book 'Multidetector computed tomography;generated virtual bronchoscopy'. Multidetector computed tomography for diaignosis of respiratory diseases. Germany: Palmarium Academic Publishing; 2016. ISBN: 978;3;659;77275;2
Authors: Article Editorial
Published: May 2017

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Impact of planned amniotomy on perinatal outcome: a randomized control trial
Authors: Joshi Shachi , Kapadia Rutul , Desai Ajesh
Published: May 2017

Background: O’Driscoll and Meagher (1968) introduced amniotomy as a component of active management of labour. Several institutions have implemented components of this management scheme with varying results. There is a risk of cord prolapse, variability in fetal heart rate, increased chances of ascending infection which may culminate in chorioamnionitis. As per certain studies, fetal outcome is similar in case of Amniotomy and spontaneous ruptured membranes. As source of great controversy, the active management of labor, as classically defined, is routinely misunderstood and misapplied in many clinical settings. Some previous randomized trials suggest Amniotomy as an effective and safe method for induction and augmentation of labour without altering rate of cesarean section while some disagree. Hence, the study was designed to evaluate the effect of amniotomy on perinatal outcome.Methods: As per the selection criteria, 250 women with singleton uncomplicated pregnancy with spontaneous onset of labour admitted in labour ward were enrolled in the study. All cases were randomized and allotted to either study group (ARM group) or control group (SRM group) equally according to random number table generated by computer. Women of study group offered amniotomy at 4cm dilatation of cervix. Before doing Amniotomy, fetal lie and presentation, engagement of head and fetal heart sounds were conformed. The results were then recorded.Results: Planned amniotomy is recommended where the clinician suspects fetal compromise as early detection of MSL in planned amniotomy improves the neonatal outcome. Planned amniotomy does not adversely affect the neonatal outcome in terms of low Apgar score at 5 min, neonatal resuscitation and NICU admission. The incidence of neonates born with MSL in planned amniotomy group is better as compared to neonates born with MSL in SRM group.Conclusions: T Planned amniotomy does not have any adverse effect on the perinatal outcome as compared to SRM group. The incidence of neonates born with MSL in planned amniotomy group is better as compared to neonates born with MSL in SRM group.
An analysis of endometrial bleeding patterns in perimenopausal women
Authors: Indrani Mukhopadhyay , P. S. Rao , S. Nataraj , Biswas Manash
Published: May 2017

Background: Perimenopause is the period surrounding menopause characterized by ovulatory dysfunction and menstrual irregularities. Taking into consideration the importance of perimenopause and its consequences, we decided to study this topic in order to know the different menstrual irregularities in relation to age, the spectrum of endometrial histopathology, in relation to various gynaecological conditions as per the PALMCOEIN classification of AUB.Methods: The study population comprised of 100 women in the age group of 40- 59 years who reported to our tertiary care centre of Armed Forces for evaluation of abnormal uterine bleeding. The study was a community based cross - sectional descriptive study. Patients were examined, using one of the three techniques – Dilatation and curettage, suction aspiration and hysteroscopy and endometrial biopsy.Results: Out of the 100 women evaluated for perimenopausal bleeding, heavy menstrual bleeding was the commonest in 53% cases. The maximum no. of cases was in 40-44-year age group (57.44 %). The clinical diagnosis of fibroid uterus was found in 45% cases, AUB (O) in 36% cases, AUB (Polyp) in 8% cases, AUB (Adenomyosis) in 9% cases and AUB (Malignancy) in 2% cases. On endometrial curettage, proliferative type of endometrium was found in 43% cases, secretory type in 18% cases and hyperplasia was found in 37% cases. Out of 2 cases of atypical hyperplasia 1 case each (50%) was found in the age group of 50-54 years and 55-59 years, respectively.Conclusions: In the present study, there was good correlation between abnormal uterine bleeding, clinical diagnosis and histopathological findings.
Study of utilization pattern and analysis of efficacy of newer angiotensin receptor blockers in patients with hypertension and type-II diabetes with or without hypertension
Authors: Samal Rajashree , Panda Jyoti Prakash , Pattnaik Kali Prasad
Published: May 2017

Background: Interventions that target blood pressure control and proteinuria, specifically interruption of the Renin-angiotensin-aldosterone system (RAAS), have been utilized in attenuating cardiovascular complications. Angiotensin receptor blockers (ARBs) have been reported to have certain advantages. The objective of the study was to evaluate and compare the utilization pattern and efficacy of different ARBs in patients with HTN and associated type-II diabetes.Methods: Hypertensive patients with or without type-II diabetes treated with ARB based regimen were selected.  The BP and 24 hours urinary albumin excretion were analysed at baseline and after three months of treatment.Results: Mean reduction in systolic blood pressure(SBP) was more with ARBs and calcium channel blocker(CCB) combination. Telmisartan alone and with ACEI reduced diastolic blood pressure (DBP) maximally in diabetic hypertensive patients. Proteinuria was significantly reduced with telmisartan (p<0.001) and olmesartan (p<0.05) based therapy. The side effects were minimal with ARB based therapy. Telmisartan was the costliest among all ARBsConclusions: There was suboptimal use of combination therapy in diabetic hypertensive patients.  Telmisartan was having the better control on 24hr urinary albumin excretion.
Effect of antiplatelet/anticoagulant agents in elderly patients of chronic subdural hematoma: a case control study from a tertiary care centre
Authors: Potdar Nilesh Vishnu , S. Suresh Kumar , Kaplinghat Bhavadasan
Published: May 2017

Background: Bleedings are well known risks of both antiplatelet and anticoagulant therapy and both therapies have historically been considered as risk factors for CSDH. The aim of the study was to evaluate the association between exposure to anticoagulant/antiplatelet therapy and chronic subdural haematoma (CSDH).Methods: Single institution case-control study was conducted in patients older than 60 years who visited our academic tertiary care Emergency Department from January 2012 to December 2016. Patients with CSDH were identified by review of case and controls were selected with a 1:3 ratio for gender, age (60 years), year of admission and recent trauma.Results: There were 124 cases and 372 controls included in the study. Both anticoagulant and antiplatelet agents were associated with an increased risk of CSDH with an OR of 1.22 (CI 95% 0.66-1.54) and 1.12 (CI 95% 0.68-1.54), respectively. While OR was 1.11 (CI 95% 0.54-2.32), 1.21 (CI 95% 0.61-2.45), and 0.53 (CI 95% 0.33-0.78) for patients receiving oral anticoagulants, ADP-antagonists, and Cox-inhibitors, respectively. History of recent trauma was an effective modifier of the association between anticoagulants and CSDH. OR of 1.69 (CI 95% 0.99-2.96) was found for patients with history of trauma and OR of 4.27 (CI 95% 2.23-8.32) for patients without history of trauma.Conclusions: Anticoagulant and antiplatelet therapy have a significant association with an increased risk of CSDH. This association appears even stronger in those patients under anticoagulant therapy, who develop a CSDH in the absence of a recent trauma.
Aetiology and outcome of anemia in patients with systemic lupus erythematosus
Authors: Sonawale Archana , Pasiddhi Suresh , Sabnis Nilakshi H.
Published: May 2017

Background: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder that is greatly subject to the combined effect of genetic, environmental, demographic and geographical factors. Hematological manifestations are very common in SLE, with many patients presenting with anemia. The cause of Anemia could be varied, with Autoimmune hemolytic anemia, anemia of chronic disease, iron deficiency being the common causes. The aim of the present study was to estimate the proportion of patients with prevalence of different causes of anemia in SLE and it‘s association between immunological and clinical parameters and to correlate the severity of anemia with SLEDAI score and SLICC/ACR score.Methods: This was an observational and prospective study conducted on 52 patients satisfying ACR criteria for SLE and WHO definition of anemia. All patients underwent baseline investigations for hematological, biochemical parameters and immunological investigations for C3 and C4. Other special investigations were done as per the treating rheumatologists’ opinion. Patients were followed up after three months to evaluate the response to therapy.Results: In this study, most of the patients were in the age group between 20-50 years (94.22%) and female:male ratio was 13:1. At presentation 55.76% patients had severe anemia, 38.46% had moderate anemia and 5.78% had mild anemia. After therapy (three months) only 3.84% patients had severe anemia. The most common cause of anemia was AIHA (38.46%).  Mean SLEDAI score at presentation was >20 but after three months therapy the score was reduced to 4. There was no correlation between aneamia and SLICC/ACR damage index.Conclusions: Anaemia usually occurs at the onset of SLE and its recurrence rate will become low after three months of therapy. SLEDAI scores, SLICC/ACR damage index and serum complement levels (C3 and C4) acts as good indices for assessment and follow up of SLE.
Экономическое содержание инфраструктуры сферы спортивных услуг
Authors: Шинкевич Алексей Иванович , Ногуманов Равиль Уелович
Published: May 2017

Рынок спортивных услуг активно развивается в России, и прежде всего, за счет проведения международных спортивных соревнований. Данная сфера услуг имеет важное социально-экономическое значение для страны, поскольку способствует не только повышению уровня здоровья населения, но и развитию национальной экономики посредством оптимального распределения ресурсов (трудовых, материальных, финансовых и т.д.). В связи с этим в статье раскрывается понятие и сущность инфраструктуры сферы спортивных услуг (в том числе классификация спортивных услуг), приводится классификация спортивных инфраструктурных объектов, описывается организационно-экономический механизм функционирования рынка спортивных услуг. Кроме того, авторами составлена схема экономического механизма рынка спортивных услуг, выявлены особенности, связанные с категорией потребителей и обоснован институциональный подход к повышению эффективности управления спортивной инфраструктурой. Также затронуты вопросы финансирования и инвестирования в развитие спортивной инфраструктуры.
Формирование механизма управления рисками на базе процессного подхода
Authors: Рыгаловский Дмитрий Михайлович
Published: May 2017

В статье затрагивается вопрос о целесообразности внедрения системы риск-менеджмента на предприятиях отечественной промышленности, в том числе химических предприятиях; говориться о рисках, сопутствующих управленческим процессам; предлагается возможный механизм управления рисками на химических предприятиях с позиций процессного подхода.
Интегративный механизм самоорганизации производственно-экономических систем: апробация и оценка эффективности
Authors: Ермакова Жанна Анатольевна , Шестакова Елена Валерьевна
Published: May 2017

В условиях становления нового технологического уклада наиболее жизнеспособными являются организации, обладающие высокой адаптационной способностью к изменениям внешней и внутренней среды. В этой связи требуется формирование принципиально новых механизмов развития предприятия, основанных на естественном потенциале самоорганизации. Актуальной является задача формирования интегрированного механизма самоорганизации предприятия, выделение структурных составляющих, а также их информационное наполнение. В статье рассмотрены вопросы формирования и практической реализации интегративного механизма самоорганизации производственно-экономических систем в промышленности. Внедрение организационного субмеханизма базировалось на определении стадии самоорганизации, выборе вариантов управленческих воздействий, построении гетерархической структуры управления и знаниевой оргкультуры. В целях внедрения экономического субмеханизма на промышленных предприятиях разработаны карты стратегических целей, установлены целевые показатели, коэффициенты самоорганизации с учетом достижения эталонных зон развития. В части мотивационного субмеханизма дифференцированы варианты стимулирующих воздействий по стадиям и фазам самоорганизации; представлены методики определения заработной платы. В рамках апробации информационного субмеханизма самоорганизации производственно-экономических систем предложены системы сбора, хранения, обработки, мониторинга информации, обеспечивающие работу интегративного механизма самоорганизации и его структурных составляющих. Теоретико-методологическое исследование и практическая апробация механизмов самоорганизации на цементных предприятиях Оренбургской области позволили обосновать направления формирования интегративного механизма самоорганизации, а также разработать алгоритм его формирования и оценки эффективности. В исследовании определена эффективность функционирования интегративного механизма самоорганизации на цементных предприятиях Оренбургской области, обоснована необходимость комплексного, интегративного использования его компонентов, обеспечивающих синергетическое взаимодействие методов, инструментов и средств отдельных субмеханизмов.
Социально-экономическая реальность России 2018
Authors: Машков Андрей Сергеевич , Максименко Александр Николаевич
Published: May 2017

В данной статье рассмотрены и проанализированы основные события, влияющие на экономическое и социальное развитие Российской Федерации. Проведен их анализ и даны выводы о перспективах развития социально-экономического благосостояния.
Субконтрактация как механизм кооперации промышленных предприятий и торговых организаций (на примере Новосибирской области)
Authors: Ершов Павел Андреевич
Published: May 2017

В последние годы стало очевидно, что замещение на внутреннем потребительском рынке импортных товаров продукцией отечественного производства является одним из условий скорейшего экономического и промышленного развития. В данной статье рассмотрен механизм субконтрактации как способ кооперации промышленных предприятий и торговых организаций, позволяющий организовывать наиболее эффективное продвижение на внутреннем рынке отечественных товаров.
В работе проведён эмпирический анализ применения торговыми сетями Новосибирской области, владеющими собственными торговыми марками, механизма субконтрактации. Проанализированы особенности применения субконтрактации в географическом и ценовом срезе предлагаемого потребителям ассортимента. Выявлены особенности кооперации региональных и межрегиональных торговых сетей с отечественными и зарубежными производителями потребительской продукции. Определены основные тенденции ценового позиционирования российских и зарубежных товаров.
Исследование деятельности регионального центра субконтрактации Новосибирской области, торгово-промышленных палат города Новосибирска и Новосибирской области показало крайне слабую активность региональных органов власти в данном направлении.
По результатам исследования предлагается активизировать деятельность регионального центра субконтрактации, целенаправленно оказывать информационную поддержку производителям продукции, содействовать в решении проблем недостатка оборотных средств.
Статья может быть интересна руководителям региональных органов власти осуществляющих промышленную и экономическую политику, руководителям промышленных и торговых предприятий, учёным, занимающимся импортозамещением и проблемами государственного стимулирования предпринимательской деятельности.
Современные тенденции развития сферы услуг в Сибирском федеральном округе
Authors: Нинштиль Елена Юрьевна , Заяц Татьяна Ивановна
Published: May 2017

В данной статье проведен обзор и анализ рынка платных услуг в Сибирском федеральном округе (далее – СФО). А именно, проведено исследование объема оказанных платных услуг по регионам в действующих и сопоставимых ценах, определена динамика роста рынка услуг. Проведенный анализ, позволил нам сделать ряд выводов об уровне платных услуг в целом по СФО и его регионам, что послужит основой для проведения более детального анализа рынка, с целью выявления слабых сторон деятельности предприятий различных отраслей сферы услуг. Данная информация в первую очередь необходима вновь открывающимся организациям сферы услуг. Необходимость состоит в том, что одной из составляющей при открытии новой организации или расширения перечня услуг является маркетинговый анализ рынка. Таким образом, данная статья предоставляет информацию о динамике развития рынка сферы услуг в СФО.
Fixed Point Theorems in Complex Valued B-Metric Spaces
Authors: Hasanah Dahliatul
Published: May 2017

A complex-valued b-metric space is a generalization of a b-metric space in which its b-metric space has complex value. It can also be considered as a generalization of a complex-valued metric space. Hence, fixed point theorems that have been studied in b-metric spaces are now of interest whether the theorems are applicable in complex-valued b-metric spaces. In this paper we have obtained some fixed point theorems in complex-valued b-metric spaces. The theorems are derived from the corresponding theorems in b-metric spaces.
Das novas escritas dramatúrgicas: aspectos rapsódicos da criação do Como se fosse [im]possível ficar aqui
Authors: Brito Nayara Macedo , Maciel Diógenes André Vieira
Published: May 2017

A partir da versão final do texto do espetáculo Como se fosse [im]possível ficar aqui, demonstram-se algumas das práticas correntes de composição dramatúrgica, caracterizada, contemporaneamente, por seu hibridismo formal. Situamos nossa discussão a partir da ideia da “restauração da narrativa” defendida por Luís Alberto de Abreu, tocando nas noções de rapsodização conceituadas por Jean-Pierre Sarrazac.
“Máquinas: múltiplas invenções de si” – percursos de uma investigação do Panacéia Delirante
Authors: Couto Lara , Flick Milena
Published: May 2017

Máquinas: Múltiplas invenções de si é um projeto de intervenções urbanas do grupo Panacéia Delirante, que utiliza partituras repetitivas para discutir o pensamento mecanicista moderno e a coisificação do corpo em máquina. A criação é fruto de uma pesquisa colaborativa, ancorada na improvisação, na paródia de comportamentos e no diálogo com a plateia. O experimento já foi apresentado na Praça Campo Grande (Salvador), no Teatro Malayerba (Quito, Equador) e em San José, Costa Rica.
Quando o pensamento se torna uma prática
Authors: Belém Elisa
Published: May 2017

O artigo apresenta um relato da participação da autora em dois congressos internacionais, na área de artes cênicas. Os eventos ocorreram em 2012, no Reino Unido. Sendo assim, compartilham-se impressões.Descrevem-se partes das programações assistidas destacando-se a prática do debate e da reflexão, assim como a prática cênica.
Laban no século XXI: Revisões necessárias
Authors: Moraes Juliana
Published: May 2017

A continuidade das idéias de Laban nos países vencedores da II Guerra dependeu de sua transformação em um sistema de análise de movimentos, que incluiu extenso mas discreto processo de renomeação, como, por exemplo: o conceito alma/espiritualidade foi adaptado para  personalidade, e a dicotomia harmonia/desarmonia foi renomeada integração/fragmentação.
“Kahlo em mim Eu e(m) Kahlo”: A Performance do meu Corpo Diferenciado
Authors: Oliveira Felipe Henrique Monteiro
Published: May 2017

Este artigo se pauta na pesquisa desenvolvida para a elaboração de dissertação de mestrado, no Programa de Pós-Graduação em Artes Cênicas da UFRN, sob orientação da Profa. Dra. Nara Salles e  objetiva refletir sobre as questões relacionadas aos artistas com corpos diferenciados nos processos de criação cênica, sobretudo no teatro pós-dramático.
Alimentos da agricultura familiar na alimentação escolar: percepções dos atores sociais sobre a legislação e sua implementação
Authors: Pozzagnol Mossmann Márcia , Teo Carla Rosane Paz Arruda
Published: May 2017

O estudo objetivou conhecer percepções de diferentes atores sociais sobre a Lei 11.947/2009 e sua implementação, nas questões da agricultura familiar. Trata de pesquisa qualitativa com 35 atores da alimentação escolar em 8 municípios catarinenses. A Lei foi percebida como vetor de alimentação saudável, fortalecimento da agricultura familiar, desenvolvimento local; sua implementação foi iniciativa dos gestores técnicos do programa. Recomenda-se incentivo à participação e protagonismo dos demais atores envolvidos.
Lessons Learned in Designing and Implementing a Mission Focused Study Abroad Course
Authors: Wise Diane , Schuessler Jenny B. , Cody Lourdes , Davison Deborah
Published: May 2017

Introduction: Based on Duffy’s (2009) Quality Caring Model and Hill and Watson’s Caring Science Curriculum Model (2011), the School of Nursing embraces the philosophy that caring collaborative relationships are the center of a culture of quality caring in nursing. Culture and cultural competence are integral to caring. Immersion experiences have been identified as impacting cultural competence (Bentley & Ellison, 2007; Kohlbry, 2016; Larsen & Reif, 2011; Long, 2012). Methodology: This paper describes the planning, implementation and lessons learned from an immersion experience as part of a mission focused study abroad course to Quito, Ecuador. Discussion: Twelve students, three faculty, and two nurse practitioners cared for approximately 100 patients per day for 10 days. Lessons learned related to faculty, students and logistics are discussed. Results: Students demonstrated positive outcomes related to critical thinking and clinical reasoning, holistic care of diverse populations, communication and collaboration, professional accountability, and effective teaching strategies.