bluuebunny/crossref_metadata_2025 huggingface dataset:
Innovative histological and histochemical characterization of tongue biopsies from patients with burning mouth syndrome
Authors: Zubiate Illarramendi Imanol , Martinez-Sahuquillo Angel , Monsalve Iglesias Fernando , Sanchez Lopez Jose Dario
Published: October 2022

Objectives

The present pilot study aims to perform an innovative histological and histochemical characterization of samples from patients with burning mouth syndrome (BMS) to correlate these findings with the clinical scenario.

Methods

To carry out this objective, the study samples were stained with the hematoxylin-eosin stain and later, an histochemical study was carried out to determine the composition of the extracellular matrix (ECM) using the stains of Alcian Blue, Picrosirius, Reticulin from Gomori and Verhoeff

Results

The results of this study revealed histological patterns compatible with cellular hypertrophy in different layers of the epithelium as well as a greater keratinization in BMS cases. On the other hand, a lower amount of proteoglycans and a greater amount of collagen fibers were observed compared to the control. In addition, older patients had fewer reticular fibers and younger patients had fewer elastic fibers compared to the control.

Conclusions

In conclusion, the present study shows the existence of a correlation between the histological patterns, age and symptoms of patients with BMS. Therefore, it is necessary to develop synergistic studies in order to assess and implement new classification systems that could improve the therapeutic approach of patients with BMS.
A Teleofunctionalist Solution to the Problem of Deviant Causal Chains of Actions
Authors: Roloff Jakob
Published: October 2022

Donald Davidson’s causal theory of actions states that actions must be rationalized and caused by a belief-desire-pair. One problem of such a causal theory are cases of deviant causal chains. In these cases, the rationalized action is not caused in the right way but via a deviant causal chain. It therefore intuitively seems to be no action while all conditions of the causal theory are met. I argue that the problem of deviant causal chains can be solved by adding a teleofunctionalist condition. This condition requires that the belief-desire pair that rationalizes an action must cause that action in aselection-historicallynormal way. I try to show that this additional condition drops counterintuitive cases of deviant causal chains out of the class of actions while being flexible enough to classify such cases as actions in which causal detours are intuitively permissible.
In situ corrosion fatigue life of 2198-T8 Al–Li alloy based on tests and DIC technique
Authors: Su Wei , Zhu Hong Mei
Published: October 2022

The advanced aluminum–lithium alloy is used in aircrafts fuselage. Based on the combination of fatigue test and digital image correlation technique, the influence of pre-corrosion and in situ corrosion damage on the fatigue performance of 2198-T8 aluminum–lithium alloy was investigated. The integrated evolution process of fatigue crack and strain distribution fields of two types of the damaged sheets were captured and evaluated by the digital image correlation technique. The results reveal a declining tendency of in situ corrosion fatigue life with the rise of solution temperature, as well as the decrease of flow rate. But, at increasing the NaCl concentration, the fatigue life tends to decrease first and then increase. The observed fatigue behavior and related phenomena are directly associated with fracture morphology such as micro-cracks and corrosion pits. The analysis indicates a competition mechanism between fatigue and corrosion, the fatigue damage dominates the failure process under lower NaCl concentration on the contrary to the higher one that the corrosion damage is the dominant factor. Considering the effect of flow rate on the surface adhesion, the crack tends to initiate at the position of low flow rate. The simulation on the flow field presents an attractive similarity with experimental results.
MicroRNAs in the auditory system: tiny molecules with big impact
Authors: Ebbers Lena , Altaf Faiza , Nothwang Hans Gerd
Published: October 2022

“Blindness separates from things; deafness separates from people.” This quote attributed to the deaf-blind author and activist Helen Keller (1880–1968) indicates the importance of proper hearing for social interaction in our society which is largely driven by acoustic communication. A major cause for auditory dysfunction lies in our genome with currently more than 100 genes linked to hearing loss. One example is the microRNA gene Mir-96 of the microRNA-183 family. MicroRNAs are small regulatory RNAs involved in the finetuning of gene expression. Analyses of transgenic mouse models established this microRNA family as a major regulator for the function of the inner ear as well as synaptic transmission in the auditory brainstem. The microRNA-183 family might therefore play an important role in coordinating the development of the peripheral and central auditory system and their specializations.
Study of activation cross sections of proton induced reactions on natBa and natCe near their threshold energy regions
Authors: Abdelshafy Mohamed Sobhi , Ali Bahaa Mohamed , Elmageed Karima Elsayed Abd , Nafie Hassan Omar , Hassan H. Ebrahim , Al-Abyad Mogahed
Published: October 2022

Activation cross-sections of the nuclear reactions natBa(p,x)135,132gLa, 135mBa and natCe(p,x)142,139,138mPr, 141,139,137mCe have been measured experimentally at the MGC-20 cyclotron, Cairo, Egypt, from their respective threshold energies up to about 14.7 MeV. Stacked foil irradiation technique and high-resolution gamma-ray spectroscopy were used. A comparison between the experimental and theoretical data derived from the nuclear model codes EMPIRE and TALYS (in the form of the TENDL library) was performed. The agreement in the low-energy region is fairly good. Integral yields of the produced radioisotopes were estimated from the present cross-section data and the results are discussed in terms of their production possibilities.
Chemometrics and infrared spectroscopy – A winning team for the analysis of illicit drug products
Authors: Deconinck Eric , Duchateau Celine , Balcaen Margot , Gremeaux Lies , Courselle Patricia
Published: October 2022

Spectroscopic techniques such as infrared spectroscopy and Raman spectroscopy are used for a long time in the context of the analysis of illicit drugs, and their use is increasing due to the development of more performant portable devices and easy application in the context of harm reduction through drug checking or onsite forensic analysis. Although these instruments are routinely used with a spectral library, the importance of chemometric techniques to extract relevant information and give a full characterisation of samples, especially in the context of adulteration, is increasing. This review gives an overview of the applications described in the context of the analysis of illicit drug products exploiting the advantages of the combination of spectroscopy with chemometrics. Next to an overview of the literature, the review also tries to emphasize the shortcomings of the presented research papers and to give an incentive to what is needed to include chemometrics as a part of the daily routine of drug checking services and mobile forensic applications.
The kagomé metals RbTi3Bi5 and CsTi3Bi5
Authors: Werhahn Dominik , Ortiz Brenden R. , Hay Aurland K. , Wilson Stephen D. , Seshadri Ram , Johrendt Dirk
Published: October 2022

The kagomé metals RbTi3Bi5 and CsTi3Bi5 were synthesized both as polycrystalline powders by heating the elements in an argon atmosphere and as single crystals grown using a self-flux method. The compounds crystallize in the hexagonal crystal system isotypically to KV3Sb5 (P6/mmm, Z = 1, CsTi3Bi5: a = 5.7873(1), c = 9.2062(1) Å; RbTi3Bi5: a = 5.773(1), c = 9.065(1) Å). The titanium atoms form a kagomé net with bismuth atoms in the hexagons as well as above and below the triangles. The alkali metal atoms are coordinated by 12 bismuth atoms and form AlB2-like slabs between the kagomé layers. Magnetic susceptibility measurements with CsTi3Bi5 and RbTi3Bi5 single crystals reveal Pauli-paramagnetism and traces of superconductivity caused by CsBi2/RbBi2 impurities. Magnetotransport measurements reveal conventional Fermi liquid behavior and quantum oscillations indicative of a single dominant orbit at low temperature. DFT calculations show the characteristic metallic kagomé band structure similar to that of CsV3Sb5 with reduced band filling. A symmetry analysis of the band structure does not reveal an obvious and unique signature of a nontrivial topology.
Archaeology, ethnography and epistemic critiques of the nation
Authors: Rizvi Uzma Z.
Published: October 2022

Much needed within scholarship related to archaeology, the construction of nations, and the politics of epistemic practice, the two books under review—Bureaucratic archaeology and Archaeology, nation, and race—are certainly welcome additions. The first, by Ashish Avikunthak, is a deep and engaged ethnographic study of the ways by which the Archaeological Survey of India (ASI) produces archaeology, and links it to religiosity, at the excavation site. Through this study, Avikunthak lays open “this social, cultural, and scientific universe of postcolonial archaeologies and demonstrate the impact of bureaucratic ontologies on epistemological practices” (p. xix). The second volume, co-authored by Raphael Greenberg and Yannis Hamilakis, can be considered autoethnographic, fashioned around conversations during a seminar at Brown University. In a series of fascinating chapter-conversations, they provide nuance to otherwise very difficult, slippery and easily conflated arguments that bring together and reflect upon the histories of archaeological imaginaries and contemporary politics of Greece and Israel/occupied Palestine. Both texts are grounded in an ethnographic modality that allows for clarity of their epistemic critiques of the nation. It is remarkable how much political work both texts are doing by carefully holding and contextualising history and contemporary politics, while also providing critical insights into the ways in which archaeology is used to further the politics of the nation.
The Effects of Nano-Montmorillonite on the Key Healing Factors of Asphalt Binders
Authors: Zhang Zhanming , Cheng Peifeng , Jin Peng , Yang Zonghao , Li Yiming
Published: October 2022

The effects of nano-montmorillonite (MMT) on the key healing factors of base asphalt and styrene-butadiene-styrene (SBS)-modified asphalt binder were investigated. The flow behavior of the nano-modified asphalt binder was measured using the viscosity-frequency sweep test, and the power law equation was calculated to determine the value of the optimum healing temperature. The healing performance of asphalt at different healing temperatures and healing times was examined using the fatigue-rest-fatigue test, and the full healing time was derived by fitting the healing function. In addition, the healing mechanism of the MMT-enhanced asphalt binder was analyzed from the perspective of surface free energy theory. The results demonstrated that increasing the MMT dose enhanced the healing performance under various healing situations, as well as the softening point and optimal healing temperature of binders. The higher binder healing efficiency was caused by the decrease in full healing time. The nanoparticles increased the surface free energy of the asphalt binder, which hastened the wetting of the microcrack interface and facilitated the healing process.
Mitigation of Karst Soil Erosion by Optimizing a Biostimulation Strategy to Induce Mineralization
Authors: Liu Shiyu , Sui Yujia
Published: October 2022

Karst soil erosion has long been regarded as a major environmental problem in many regions around the world, especially in Southwest China. Based on biomineralization, a biostimulation strategy optimized by the Plackett–Burman (PB) central composite design (CCD) method was proposed to improve the erosion resistance of a red karst clay soil. First, the key components of the stimulation solution were selected by the PB design. Then, a CCD was used to obtain the optimal ratio for each component of the stimulation solution. Finally, surface strength tests, calcium carbonate content tests, infiltration tests, wind erosion tests, and rainfall erosion tests were conducted to evaluate the effect of the biostimulation strategy on red clay erosion resistance and on the mechanical properties of the soil. The influence of cementation solution concentrations and treatment cycles were further analyzed based on test results. The microstructural features of the samples were also analyzed to elucidate the mechanisms of surface erosion control. The results showed that the proposed biostimulation strategy mitigated red clay erosion. Even at a wind speed of 30 m/s, the weight loss of all the biostimulation strategy-treated samples was almost negligible. After 10 cycles of biostimulation treatment, the maximum amount of soil erosion in the rainfall erosion test was reduced by a factor of 10.82. The crust formed on the surface of the samples treated with the biostimulation treatment had higher strength and lower permeability, and it effectively resisted soil erosion. The crust was formed because of binding of the biomineralization product calcium carbonate to soil particles. The higher the calcium carbonate content was, the stronger the erosion resistance of the samples. A comprehensive assessment of the treatment effect, efficiency, and cost showed that 7 cycles of biostimulation treatment with a 1.0 M cementation solution was optimal for the mitigation of red clay erosion.
Molecular mechanisms of transporter regulation and their impairment in intrahepatic cholestasis
Authors: Li Xiping , Zu Yue , Li Guodong , Xiang Dong , Zhang Chengliang , Liu Dong
Published: October 2022

Intrahepatic cholestasis (IC) is a liver disease caused by disorders in bile formation and excretion, owing to structural and functional abnormalities in hepatocytes and/or bile capillaries. IC is commonly caused by hepatitis virus, alcohol consumption, drug-induced liver damage, autoimmune liver disease and heredity. In the absence of effective treatment, IC can progress to liver fibrosis, cirrhosis and ultimately liver failure. However, the mechanisms underlying IC remain poorly understood. IC is believed to be closely associated with changes in the transcription, function and localization of hepatocellular transport proteins. To better understand the molecular mechanisms of transport proteins in IC, herein, we review the roles of these transport proteins and discuss their underlying regulatory mechanisms in IC. Our aim is to provide a reference for understanding IC pathogenesis and developing effective drug therapies.
Lacunes et apports des accélérateurs et des incubateurs universitaires aux écosystèmes entrepreneuriaux
Authors: Ricard Julie , Motaghi Hamed , Etemad Hamid
Published: October 2022

Les universités fournissent une grande connectivité et légitimité pour les entreprises en démarrage (start-ups) résidentes. Pourtant, le taux de diplomation des start-ups résidentes demeure inférieur à d’autres incubateurs.  Quatre éléments de plus-value sont constatés : le réseautage, le mentorat, la connectivité et l’amélioration de la marque. Nous suggérons donc qu’il est nécessaire pour les incubateurs universitaires de développer un modèle de connectivité structurelle. Après l’examen de quatre incubateurs canadiens, nous proposons un modèle de connectivité structurelle dans lequel des incubateurs ont développé des modèles d’affaires où les parties prenantes au financement sont impliquées dans d’autres volets critiques du processus d’incubation. Dans d’autres cas, les incubateurs s’appuient sur l’expérience de la direction pour incarner cette connexion entre les composantes du processus d’incubation. Les incubateurs au plus haut classement démontrent une connectivité structurelle et agentique, laissant croire qu’une connectivité agentique est nécessaire au développement d’une connectivité structurelle. De plus, la connectivité structurelle se caractérise par le développement d’un écosystème entrepreneurial agile et autosuffisant.
La corruption internationale et nationale : une analyse des dispositions normatives canadiennes applicables dans les secteurs publics et privés
Authors: Simard Jeanne , Desjardins France
Published: October 2022

Bien qu’il soit difficile d’estimer avec précision les impacts socioéconomiques pour les pays, certaines études démontrent que les faits de corruption brisent le tissu social des communautés et piétinent la notion d’intérêt général en interférant dans le fonctionnement des marchés, des entreprises et des États. Devant ce « mal collectif » international, la lutte à la corruption et les efforts pour la prévenir sont devenus, depuis les années 1990, une priorité dans la réforme des pays et de leurs institutions. L’objectif principal de cet article se veut une synthèse pour guider les gestionnaires des organisations publiques et privées désirant se démêler dans les écheveaux normatifs du droit international et national canadien en matière de corruption. Nous verrons aussi quelques décisions significatives des tribunaux canadiens à ce sujet. Le droit criminel économique est un secteur du droit qui s’est considérablement modifié au fil des ans et qui subira encore des changements significatifs dans un plus ou moins bref avenir. Il est important que les gestionnaires soient au fait de cette évolution puisque ces normes peuvent avoir des impacts considérables sur la gestion et sur la gouvernance de leur organisation.
IGSF1 mutations are the most frequent genetic aetiology of thyrotropin deficiency
Authors: Fourneaux Rachel , Reynaud Rachel , Mougel Gregory , Castets Sarah , Bretones Patricia , Dauriat Benjamin , Edouard Thomas , Raverot Gerald , Barlier Anne , Brue Thierry , Castinetti Frederic , Saveanu Alexandru
Published: October 2022

Design

Thyroid-stimulating hormone deficiency (TSHD) is a rare disease. It may be isolated, secondary to abnormalities of genes involved in TSH biosynthesis, or associated with other pituitary deficits or abnormalities of genes involved in pituitary ontogenesis. Several genes are involved in thyrotroph development and function.

Objective

Our aim was to determine the genetic causes of TSHD, either isolated (ITSHD) or associated with somatotroph deficiency (TSHD-GHD), in the cohort of patients from the GENHYPOPIT network.

Methods

Next-generation sequencing (NGS) analyses were performed as a panel of genes on a cohort of patients with non-syndromic ITSHD or TSHGHD. The variants were classified according to the American College of Medical Genetics classification reviewed by the NGS-Diag network and correlated with the phenotype. Class 3, 4, and 5 single-nucleotide variants were checked by Sanger sequencing and copy number variants by multiplex ligation-dependent probe amplification (MLPA).

Results

A total of 64 index cases (22 ITSHD and 42 TSHD-GHD) were included in this cohort. A genetic cause was identified in 26.5% of patients, with 36.3% in the ITSHD group (variants in TSHβ and IGSF1) and 21.4% in TSHD-GHD (variants in IGSF1, TSHβ, TRHR, GH1, POU1F1, and PROP1). Among the pathogenic and likely pathogenic variants identified, 42% were in IGSF1, including six not previously reported.

Conclusion

Our results show that IGSF1 variants represent the most frequent aetiology of TSH deficiency. Despite a systematic NGS approach and the identification of new variants, most patients remain without a molecular diagnosis. Larger scale studies, such as exome or genome studies, should be considered in the future.
Jóvenes, hip hop y cine latinoamericano
Authors: Montoya Wilfredo
Published: October 2022

El presente artículo aporta evidencia sobre el interés creciente del cine latinoamericano por el hip hop. La narración cinematográfica de estos filmes retrata las vidas de jóvenes de clases populares que enfrentan situaciones marcadas por la violencia y profundas desigualdades sociales, a través de la práctica del rap, break dance, grafiti y DJing, componentes de esta cultura. El artículo brinda un recuento de películas y documentales realizados en ocho países de Latinoamérica en la última década. Analiza sobre todo tres películas, estrenadas en 2021: Así crecí, del cineasta mexicano Jos Macías; Cato, del director argentino Peta Rivero y Hornos; y La ciudad de las fieras, del realizador colombiano Henry Rincón. Plantea que estas cintas aportan una reflexión estética realista, crítica y confluyente con una perspectiva descolonial de sus respectivas sociedades, junto a una lectura de un sector social prioritario como las juventudes populares, útil para comprender sus características actuales y perspectivas de futuro.
Hipertextualidad en Concierto barroco de Alejo Carpentier
Authors: Hernández Guerra Ana María
Published: October 2022

A partir de los conceptos sobre hipertextualidad como una de las formas de la transtextualidad, planteados por Gérard Genette, se analiza la novela Concierto barroco de Alejo Carpentier, desde los textos de partida, o hipertextos, que los originaron hasta los textos de llegada o hipotextos; e incluso las melodías que también la inspiraron, mediante otra modalidad de la hipertextualidad denominada transmodalización. Lo novedoso en este artículo es la profundización en la hipertextualidad, como forma específica de la intertextualidad.
Construcción del discurso de normalización del aborto en TikTok: análisis bajo la teoría del framing visual
Authors: Quintana Morales Sthefany Faride
Published: October 2022

El presente trabajo busca identificar los principales encuadres en la construcción de discursos a favor del aborto en la red social TikTok. El estudio se realiza por medio del análisis del discurso y el paradigma del framing visual mediante la revisión de las piezas audiovisuales —videos— en cuatro dimensiones: verbal, visual, aural e ideológico. Entre los principales resultados se encontró que los diferentes encuadres identificados promueven la resignificación del aborto como una práctica liberadora, heroica, cotidiana e, incluso, divertida, a través del uso de recursos audiovisuales con estructura lúdica, que apelan a las emociones antes que a la racionalidad.
Lawrence La Fountain-Stokes. Translocas. The politics of Puerto Rican drag and trans performance. Ann Arbor, University of Michigan Press, 2021. 337 pp.
Authors: Villanueva-Jordán Iván
Published: October 2022

El libro de Lawrence La Fountain-Stokes apunta a ser una obra integral y abarcadora en relación con los trabajos de representación de la transgeneridad en medios televisuales, fílmicos, artísticos, literarios y también en géneros de no ficción, como la investigación etnográfica y sociológica. A pesar de este macroobjetivo o, más bien, reconociendo la complejidad de dicha tarea, el compromiso reflexivo del autor permite reconocer su posicionamiento frente a los artefactos y performances que analiza, lo que conlleva valorar sus interpretaciones y argumentación como un ejercicio académico comprometido, pero a la vez riguroso y crítico, sobre lo trans y lo drag en las acciones de sujetos, artistas y activistas, latinxs y latinoamericanxs. Así, el libro gira en torno a una apuesta conceptual y neológica o neonímica: la transloca, como clave articuladora de acciones transgresoras y disruptivas de los discursos de género, de la sexualidad cisheteronormativa, de la racialización, del capital, entre otros. En los siete capítulos del libro, La Fountain-Stokes despliega un repertorio conceptual interdisciplinar, notorio en la manera en que los objetos de análisis, como ejemplo, un programa de telerrealidad, entran en diálogo con la teoría sociolingüística, pero a la vez con estudios críticos sobre la raza y la pobreza. Asimismo, aunque no se propone un diseño metodológico explícito, el trabajo de discusión y transferencia teórica entre los casos analizados demuestran nuevamente la reflexividad académica del autor en la confección de cada capítulo. En particular, en torno a la reflexividad del autor sobre su investigación y lugar de enunciación, la sección sobre Lola von Miramar en la parte introductoria es un breve ensayo sobre los lugares de representación del dragqueenismo, así como del miedo y vértigo que implica transgredir la normativa de género mediante la encarnación travesti; estos son episodios que La Fountain-Stokes relata haber atravesado y que señalan su posicionamiento en relación con lo que teorizará en el resto del libro.
Mercedes Cabello. El Conspirador (autobiografía de un hombre público). Edición crítica de Mónica Cárdenas Moreno. Lima, Ediciones MYL, 2021. 294 pp.
Authors: Vargas de la Vega Luz
Published: October 2022

Los dolorosos estragos de la pandemia que asoló al Perú entre 2020 y 2021, además de ubicarlo como el primer país en el mundo con mayor cantidad de muertes por el covid-19, desnudaron al límite la ya evidente precariedad de nuestro sistema sanitario, educativo y laboral, y su relación con los altísimos niveles de corrupción e ineptitud del poder político.
Pablo Landeo Muñoz. Lliwyaq. Lima, Pakarina Ediciones, 2021. 117 pp.
Authors: Krögel Alison
Published: October 2022

Desde hace muchos años, el escritor e intelectual peruano Pablo Landeo Muñoz ha participado de manera activa en el movimiento de promover la creación y difusión de la literatura quechua en una variedad de géneros y espacios para públicos diversos. Tal vez es mejor conocido por ganar el Premio Nacional de Literatura, en la categoría Lenguas Originarias, en 2018 con su novela (monolingüe) quechua Aqupampa y por ser el cofundador y director de Atuqpa chupan, la revista de crítica literaria quechua (monolingüe). También ha publicado la colección de relatos Wankawillka (2013, bilingüe), y los libros de poesía en castellano Los hijos de Babel (2011) y Nocturnos (2015). Además de esta producción considerable de creación literaria, cabe destacar que Landeo Muñoz es asimismo antropólogo y experto en la tradición oral andina-quechua.
Setenta e cinco anos de publicação de O ex-mágico (1947), de Murilo Rubião, e a instauração da ficção do insólito absurdo no Brasil
Authors: García Flavio , Silva Luciana Morais da
Published: October 2022

Ainda que, de fato, injustiças à parte, relegando ao esquecimento determinados autores e obras, a crítica tenda a reconhecer que, em 1855, com a publicação da antologia de contos Noite na taverna, de Álvares de Azevedo, sob o pseudônimo Job Stern, se inaugurou no Brasil a ficção fantástica, somente a partir do final da primeira metade do século XX, com Murilo Rubião, o fantástico começou a ganhar alguma visibilidade. O historiador e crítico literário Antonio Candido, ao comentar a nova narrativa brasileira, que despontaria a partir da terceira década desse século, observa que, "[c]om o livro de contos O ex-mágico (1947), [...] instaurou-se no Brasil a ficção do insólito absurdo" (Candido, 1987, p. 208). Dos quinze contos que integram o livro, apenas dois destoam completamente do que se possa conceituar insólito absurdo. Os demais correspondem perfeitamente ao discurso fantástico contemporâneo, seja pelo procedimento da actorialização, da espacialização, da temporalização ou da efabulação insólita, isolada ou combinadamente (Prada Oropeza, 2006).
КОМП’ЮТЕРНЕ МОДЕЛЮВАННЯ РУХУ РІДИНИ В СОПЛАХ ВЕНТУРІ РІЗНИХ КОНФІГУРАЦІЙ
Authors: Авдєєва Л. , Макаренко А. , Декуша Г.
Published: October 2022

Вступ. Гідродинамічна кавітація як ефективний спосіб локальної концентрації енергії для створення потужних динамічних ефектів широко застосовується для інтенсифікації багатьох енергоємних процесів обробки складних гетерогенних дисперсних систем.Проблематика. Висока вартість обладнання для фізичного експерименту й труднощі відтворення в лабораторних умовах складних гідродинамічних процесів спричиняють необхідність використання методів їхнього моделювання. Останнім часом математичне та комп’ютерне моделювання перетворилося в одну з найбільш ефективних технік.Мета. Прогнозування поведінки руху рідини всередині сопел Вентурі різних конфігурацій при зміні теплотехнологічних параметрів за допомогою обчислювального пакету ANSYS Fluent.Матеріали і методи. Використано алгоритм Simple методу Патанкар із залученням протипотокової схеми другого порядку точності для конвективних членів в рівнянні збереження імпульсу, для рівняння кінетичної турбулентної енергії і рівняння дисипації турбулентної енергії; застосовано модифіковану k-ε модель турбулентності «Realizable» та Ейлерову модель Mixture (модель багатофазної суміші). Для генерації розрахункової сітки використано стандартний пакет Ansys ICEM CFD.Результати. Обрана модель для комп’ютерного прогнозування показала свою ефективність і дозволила встановити деякі закономірності руху рідини по осі сопла Вентурі. За результатами моделювання побудовано залежності зміни показників тиску при зміні діаметра горловини й кута розкриття дифузору сопла Вентурі. Показано, що найбільша інтенсивність кавітаційного впливу досягається в дослідному соплі з кутом розкриття дифузора αdif = 12° для всіхдіаметрів горловини сопла.Висновки. Застосування вузькоспеціалізованих програмно-моделюючих систем дозволяють краще зрозуміти поведінку течії в закритих каналах різних профілів. Комп’ютерне моделювання руху рідини в соплах Вентурі дозволило забезпечити прогнозування процесів виникнення і розвитку гідродинамічної кавітації на різних відрізках.
EFFECTIVE MANAGEMENT OF PROTECTED AREAS AND THE ROLE OF FUNCTIONAL ZONING IN ITS ASSESSMENT METHODS
Authors:   Institute of Geography of the National Academy of Science of Ukraine, Kyiv, Varukha A.V. ,   Chornobyl Radiation and Ecological Biosphere Reserve, Kyiv
Published: October 2022

The article aims to define the role of functional zoning in the effective management of protected areas and to analyze the main methods of assessing the protected area (PA) management effectiveness. The research was performed using general scientific research methods. Methods and factors that should be taken into account when developing functional zoning are highlighted. The significant potential for the use of functional zoning to improve PA’s management is pointed out, in particular, through methodological improvement, implementation of international experience, including IUCN recommendations, and ensuring the balance between zones. The analysis of the basic methods of protected areas management effectiveness is carried out. The role of spatial organization and functional zoning in achieving high-performance indicators of PAs management in protected areas management effectiveness assessments is indicated. For the first time, the peculiarities of the integration of the indicators of the criterion of functional zoning into the methodology of assessing the effectiveness of management of PAs and the need for its wider implementation in these methodologies are identified.
Impact of CSF Meningitis and Encephalitis Panel on Resource Use for Febrile Well-Appearing Infants
Authors: DesPain Angelica W. , Pearman Ryan , Hamdy Rana F. , Campos Joseph , Badolato Gia M. , Breslin Kristen
Published: October 2022

OBJECTIVES

To determine whether the BioFire FilmArray Meningitis/Encephalitis (ME) panel is associated with decreased resource use for febrile infants. The ME panel has a rapid turnaround time (1–2 hours) and may shorten length of stay (LOS) and antimicrobial use for febrile well-appearing infants.

METHODS

Retrospective cohort study of febrile well-appearing infants ≤60 days with cerebrospinal fluid culture sent in the emergency department from July 2017 to April 2019. We examined the frequency of ME panel use and its relationship with hospital LOS and initiation and duration of antibiotics and acyclovir. We used nonparametric tests to compare median durations.

RESULTS

The ME panel was performed for 85 (36%) of 237 infants. There was no difference in median hospital LOS for infants with versus without ME panel testing (42 hours, interquartile range [IQR] 36–52 vs 40 hours, IQR: 35–47, P = .09). More than 97% of infants with and without ME panel testing were initiated on antibiotics. Patients with ME panel were more likely to receive acyclovir (33% vs 18%; odds ratio: 2.2, 95%: confidence interval 1.2–4.0). There was no difference in median acyclovir duration with or without ME panel testing (1 hour, IQR: 1–7 vs 4.2 hours, IQR: 1–21, P = .10). When adjusting for potential covariates, these findings persisted.

CONCLUSIONS

ME panel use was not associated with differences in hospital LOS, antibiotic initiation, or acyclovir duration in febrile well-appearing infants. ME panel testing was associated with acyclovir initiation.
Rare Presentation of Cardiac Sarcoidosis With Recurrent Large Pericardial Effusion and Stress-induced Cardiomyopathy
Authors: Qasim Riyadh , Alkatout Khalid , Qaddoura Fatema , Nagib Ayman
Published: October 2022

A 65-year-old woman with type 2 diabetes and no significant past medical history, had presented to another hospital with a 2-week history of progressive dyspnoea, orthopnoea and, lower limb oedema. Echocardiography revealed a large pericardial effusion with echocardiographic signs of increased intrapericardial pressure. An emergency pericardiocentesis was performed. After 1 week, the patient was admitted to King Fahd Military Medical Complex (Dhahran, Saudi Arabia) because of re-accumulation of the large pericardial effusion, which mandated another pericardiocentesis. CT of the chest revealed enlarged mediastinal lymph nodes. Video-assisted thoracic surgery was performed to obtain a pericardial window and a biopsy from the mediastinal lymph nodes, which revealed non-caseating granuloma, highly suggestive of sarcoidosis. A few days after surgery the patient experienced a neurogenic bladder, acute renal shutdown, and metabolic acidosis, during which she developed stress-induced cardiomyopathy that improved a few days later. The patient’s symptoms improved within 2 weeks after receiving corticosteroids.
Analysis of Human Resource Management in The Administration of Food Barns during the COVID-19 Pandemic in East Java, Indonesia
Authors: Gunawan Cakti Indra , Pudjiastuti Agnes Quartina , Yulita
Published: October 2022

Purpose: This study aims to analyze the evaluation of human resources in managing food barns and how to maximize human resources in managing food barns as a form of service to meet community needs during a pandemic. Design/Method/Approach: The research method uses a literature review study design and a descriptive qualitative approaching method. Findings: The results of the research show that in order to improve the effectiveness of human resources, it can be based on technology and information. As well as optimizing human resources, it can be done through trainings that require community and government participation. Theoretical Implications: This study contributed especially in the existence of literature about the management of food barns in rural area during the time of economic crisis and COVID-19 Pandemic.   Practical Implications: Rural area apparatus in the region of East Java, Indonesia must improve their skill about the information system to menage food barns not in traditional way. Originality/Value: This study is diffrent from any other studies in term of human resources, this is because this study has a characteristic about the use of technological information on how to manage the food barns at the moment of COVID-19 Pandemic. Research Limitations/Future Research: Further research to analyze options to optimize human resources in food barn management. Paper type: Empirical
Determinants of Social Media Marketing Adoption in Small, Medium and Micro Enterprises during the Covid-19 pandemic
Authors: Ramphele Mmatsela , Msosa Steven Kayambazinthu
Published: October 2022

Purpose: This study aims at assessing the determinants of Social Media Marketing adoption in small, medium and micro enterprises (SMMEs) during the Covid-19 pandemic.
Design / Method / Approach: The study seeks to understand the viewpoints and motives for employing social media campaigns. Thus, a structured quantitative questionnaire was provided to 150 respondents to assess social media marketing in their firms, using convenience sampling. A descriptive analysis of data was undertaken using the SPSS.
Findings: The study's findings showed that most respondents agreed with items related to Social Media Marketing’s facilitating conditions, perceived ease of use, perceived usefulness and cost implications.
Theoretical Implications: The study contributes to the extant literature on Social Media Marketing during the Covid-19 pandemic in the developing world, wherein poor infrastructure, bureaucracy and culture play an important role in business performance.
Practical Implications: SMME owners and managers should encourage their employees and customers to use social media regularly in order to drive traffic towards the business.
Originality / Value: The study is unique as it analyses Social Media Marketing during a turbulent time in which the Covid-19 pandemic is wreaking havoc on economies globally.
Research Limitations / Future Research: Researchers should consider analysing the effect of Covid-19's lockdown restrictions on specific sectors in an attempt to facilitate tailor-made solutions to the problem.
Paper type: Empirical
Work and Espoused National Cultural Values of Generation Z in Austria
Authors: Aldjic Klaudia , Farrell Wendy
Published: October 2022

Purpose: Employers face the challenge of preparing for a new, upcoming generational cohort that is different in its expectations of the workplace, which goes hand-in-hand with its values. Therefore, Generation Z in Austria must receive detailed attention because it will make up a significant proportion of the workforce in the future. Questions will emerge about how to recruit this cohort or how to retain them. This research fills this gap by analyzing their espoused national cultural values and corresponding work values while considering the implications of the SARS-CoV-2 pandemic.

Design/Method/Approach: This quantitative research surveyed 137 Austrians from Generation Z.

Findings: The results show a low Power Distance score, concluding that Austrian Generation Z does not prefer unequally distributed power; a low preference for Collectivism, a higher preference for Uncertainty Avoidance, and lower Masculinity. In terms of work values, Austrian Generation Z demonstrated the strongest preference for intrinsic and social rewards and emphasized the importance of offering benefits such as remote work opportunities and flexibility in scheduling work.

Theoretical Implications: This study shows that espoused national cultural values impact work values in the context of Austrian Gen Z. Thus, both the espoused national cultural framework and the work values framework can be considered suitable for investigating values differences.

Practical Implications: Human Resources practices should be adapted to successfully recruit and retain Austrian Generation Z.

Originality/Value: This research is among the early attempts to not only understand how espoused national cultural values and COVID impact the work values of Generation Z in Austria.

Research Limitations/Future Research: The smaller sample size and the over representation of females impact the extent to which findings can be generalized to all of Generation Z in Austria. Future research should expand the sample within Austria and internationally.

Acknowledgments: This paper is the further development of the first author's thesis. Thank you to all of those who contributed to and supported these efforts.

 Paper type: Empirical
ВПЛИВ рH-КОРЕГУЮЧОЇ ОБРОБКИ НА ГЕЛЕУТВОРЮЮЧІ ВЛАСТИВОСТІ ІЗОЛЯТУ ПРОТЕЇНУ НАСІННЯ ГАРБУЗА
Authors: Гао Дан , О. Геліх Анна , М. Філон Андрій , Дуань Чженьхуа , Василенко Ольга О.
Published: October 2022

Обробка зі зміною pH – це новий метод модифікації білка, який може поліпшити функціональні властивості і застосування білка в харчових продуктах. У цьому дослідженні було вивчено вплив методу зміни pH на властивості гелю, індукованого нагріванням ізолятів білка насіння гарбуза (ІБНГ). Обробка зі зміною pH - це новий метод модифікації білка, який може поліпшити функціональні властивості і застосування білка в харчових продуктах. У цьому дослідженні було вивчено вплив методу зміни pH на властивості гелю, індукованого нагріванням ізолятів білка насіння гарбуза (ІБНГ). ІБНГ, оброблені при різних значеннях pH (pH 2, pH 4, pH 6, pH 8, pH 10 і pH 12), були позначені як ІБНГ 2, ІБНГ 4, ІБНГ 6, ІБНГ 8, ІБНГ 10 і ІБНГ 12 відповідно. Були досліджені водопоглинаюча здатність та текстурний аналіз (твердість, адгезивність і когезивність) гелів, утворених за допомогою ІБНГ, обробленого за допомогою різних змін pH. У порівнянні з контролем, водопоглинаюча здатність ІБНГ 2, ІБНГ 4 і ІБНГ 12 значно збільшилася (p < 0.05). Текстурний аналіз гелів ІБНГ показав, що тільки твердість ІБНГ 6 показала підвищений (p < 0.05) значення. В’язкість зразків ІБНГ після обробки при pH 2, pH 4, pH 6, pH 8, pH 10 і pH 12 не показала значущої (p < 0.05) різниці в порівнянні з контролем. Крім того, адгезія ІБНГ 2, ІБНГ 4 і ІБНГ 10 показала значного (p < 0.05) зниження, в той час як адгезійна здатність ІБНГ 6, ІБНГ 8 і ІБНГ 12 не показала якої-небудь значущої (p < 0.05) різниці в порівнянні з контролем. Ці результати показали, що обробка зі зсувом рН може бути зручним і економічним методом зміни властивостей гелю PSPI, що дасть фундаментальні знання для подальшого використання PSPI в харчових продуктах.
Specificity of US President J. Biden’s Evaluativity of the Black Lives Matter Protest Movement in Social and Political Discourse
Authors: Aksenova Tatiana V. , Chapaev Bulat Kh.
Published: October 2022

Introduction. Due to the development of information and communication technologies, the impact of the media on the population has increased significantly. Journalistic discourse implements one of its main functions – the function of influence and manipulation – by referring to various means of evaluation. In this case, any object or phenomenon of reality, as well as current events, can be evaluated.

Materials and Methods. This work examines the evaluative lexical-semantic units that describe the attitude of the 46th President of the United States, J. Biden, to the events of 2020 associated with the Black Lives Matter protest movement. Practical material is selected from influential American news portals. Research methods include the continuous sampling method and the method of contextual analysis.

Results. In the course of the study, components of an evaluative nature were selected. An analysis was given of the purpose of evaluative tools in a particular context, and the evolution of the attitude of the English-language media to the position of J. Biden in connection with the Black Lives Matter movement was traced.

Discussion and Conclusion. Based on the results of the study, a conclusion was made about the significant role of the media in shaping public opinion. The evolution of the media’s attitude to the president’s position is traced.
Food Culture in Russia: Socio-Philosophical Content
Authors: Stozhko Dmitrii K. , Konstantin P. Konstantin P.
Published: October 2022

Introduction. The purpose of this study is to analyze the impact of the state of food culture in the Russian Federation on the quality of life of people and assess its transformations (food supply and public catering) in modern conditions.

Materials and Methods. The study used structural-functional and program-targeted approaches, methods of analysis, synthesis, generalizations and axiology, as well as historical-retrospective, historical-genetic and hermeneutical methods for studying problematic issues of modern food culture in the Russian federation.

Results. Various theoretical and methodological approaches to the formulation and solution of issues of the development of food culture in Russian science are identified and characterized. An assessment of the real state of the food problem in the country is given. The principles of the culture of public catering of the population are revealed. The position is substantiated that against the background of the achievement of the main quantitative indicators in solving the problem of food security of the Russian Federation, the task of guaranteeing the necessary quality of food and creating a reliable system of food supply for citizens has become on the agenda. To do this, it is proposed to eliminate the legislative conflict related to the fact that the provisions of the Federal Law “On the Quality and Safety of Food Products” dated March 01, 2020 do not directly apply to relations arising between suppliers of food products and organizations providing public catering services. A proposal has been formulated on the advisability of developing and adopting a special Federal Law “On the organization of catering for the population in the Russian Federation”.

Discussion and Conclusion. On the basis of different scientific concepts (A. A. Kaufman,

A. F. Fortunatov, A. V. Chayanov, M. F. Shcherbina, A. A. Chuprov, etc.), the authors have determined the models of food culture that have developed in modern conditions, and formulated the principles of organizing effective food supply.
Specific Character of Linguistic Personality Education in the Noble Society of the Second Half of the 18th – the Beginning of the 19th centuries
Authors: Zetkina Irina A. , Zhindeeva Elena A. , Barsukova Elena V. , Abisheva Saule Dzh.
Published: October 2022

Introduction. Noble society traditions are not simply a base for Russian multilingual culture; they remain the historical basis of the reproduction of human intellectual capital as a basis of the world organization. In this connection the mechanisms of linguistic personality educational processes within the framework of the noble society are of considerable interest for modern researchers and, in our opinion, they require certain elucidation and some comments.

The purpose of the article is to analyse communicative process in the noble environment of the 18th – the 19th centuries as a specific model of personality upbringing.

Materials and Methods. The material of the research is Russian fiction, autobiographical literature and memoirs of the 18th and the 19th centuries. The methods used in the article are: method of system analysis of sources, content-analysis method, sociocultural, axiological, phenomenological, hermeneutical and comparative-historical approaches to the study of cultural phenomena.

Results. The hypothesis that specific character of linguistic personality upbringing of the second half of the 18th – the beginning of the 19th centuries was closely connected with the tutorship institute as well as with the large scale of home education is empirically confirmed and corroborated. Didactic approach to the noble heirs, aimed at multilingual personality formation quite often came to the readiness of of-springs to freely master both oral and written forms of speech in a foreign language (mainly the French language). Moreover, the aspiration of the pupils to fix and pass their speech and thinking experience in a foreign language as well as the examples of its use in the practice of speech culture and behaviour become the standard of educational processes.

Discussion and Conclusions. The results of the research can be used for the development of the syllabuses connected with the history of bilingual teachings, the history of pedagogy and the theory of education, which, from the practical point of view, will be of use for the perfection of the syllabus for institutions of higher education and the improvement of the quality of literary works analysis. The value of the research is in the context analysis.