bluuebunny/crossref_metadata_2025 huggingface dataset:
Kebijakan Pertahanan Maritim Indonesia dan Peningkatan Kerjasama Regional di ASEAN
Authors: Witono Jarot , Yuliantini Yuliantini , Hardiman Hardiman
Published: October 2024

Indonesia sebagai negara kepulauan terbesar di dunia, memiliki peran penting dalam kerjasama pertahanan maritim ASEAN, khususnya dalam meningkatkan kerjasama regional. Studi ini mengeksplorasi bagaimana Indonesia, melalui inisiatif Global Maritime Fulcrum (GMF) dan Omnibus Bill on Maritime Security, menghadapi tantangan dalam koordinasi keamanan maritim dan memperkuat posisinya di tingkat regional. Dengan menggunakan metode kajian dokumen, penulisan jurnal ini mengkaji dokumen-dokumen kebijakan, laporan lembaga internasional dan publikasi akademik yang relevan dari tahun 2000-an hingga saat ini. Hasilnya menunjukkan bahwa meskipun terdapat kesenjangan kapasitas operasional yang signifikan, kerjasama internasional, terutama dalam pertukaran intelijen dan pengadaan peralatan, dapat meningkatkan efektivitas keamanan maritim Indonesia. Penulisan jurnal ini juga menyoroti bagaimana Indonesia memanfaatkan kekuatan laut sesuai teori Mahan untuk mendukung keamanan dan kemakmuran nasional serta regional.
A concorrência desleal no e-commerce da importação: um estudo sobre a decisão de compra do público universitário
Authors: Aparecido Fortuoso da Silva Givan , Ferreira dos Santos Karoline , Kitazima Kátia , Moraes Lima Trindade Letícia , Da Silva Ribeiro Lucas
Published: October 2024

Considerando o crescimento e o amadurecimento do e-commerce brasileiro promovidos pela COVID-19, ainda mais no que se refere ao e-commerce na importação, e a preocupação quanto às ofertas deste segmento estarem amparadas em práticas desleais de comércio, definiu-se como objetivo geral para o presente estudo: identificar se a concorrência desleal no e-commerce da importação influencia na decisão de compra do público universitário. Como objetivos específicos foram definidos: averiguar os fatores que influenciam a decisão de compra do público universitário, identificar a compreensão sobre e-commerce e concorrência desleal. Compreendeu a amostra da pesquisa os alunos do Curso Superior em Comércio Exterior de uma instituição de ensino pública situada na Região Oeste da Grande São Paulo. A metodologia baseia-se numa pesquisa survey, com abordagem quantitativa, utilizando-se de uma Matriz de Amarração e da escala Likert para elaboração e coleta de dados por meio de um questionário eletrônico. Realizou-se uma análise descritiva dos dados coletados, que permitiu concluir que a concorrência desleal influencia na decisão de compra do público universitário, porém não sendo um fator determinante.
Peranan Guru PAI dalam Meningkatkan Kedisiplinan Shalat Berjamaah Siswa
Authors: Azis Abdul , Abnisa Almaydza Pratama
Published: October 2024

This study aims to find out the Role of PAI Teachers in Improving Student Congregational Prayer Discipline. This study uses a descriptive method with data collection techniques using field observation, interview, and documentation methods. Data analysis was carried out qualitatively consisting of data reduction, data presentation, and conclusion drawn. The results of the analysis show that PAI teachers have a very strategic role in efforts to improve the discipline of congregational prayer among students. Through a comprehensive understanding, good example, and intensive mentoring, PAI teachers can be the driving force for the formation of a strong attitude of discipline and commitment to students to perform congregational prayers. The importance of continuous education and training for teachers to improve their skills and insights cannot be ignored in today's linear series. PAI teachers must remain relevant to developments in the world of education and continue to develop as professionals. PAI teachers have a very strategic role in efforts to improve the discipline of congregational prayer among students. Through a comprehensive understanding, good example, and intensive mentoring, PAI teachers can be effective agents of change in shaping the disciplined and religious character of students
PERKEMBANGAN INDUSTRI HALAL DI INDONESIA
Authors: . Sri Kasnelly
Published: October 2024

Familiar permasalahan halal dan haramnya suatu produk. Mengkonsumsi makanan atau produk yang tidak memiliki kejelasan terkait halal tentu dilarang,namun saat ini akan diragukan bila dalam suatu produk tidak dapat menemukan logo halalnya. Dan biasanya baik umat Muslim ataupun umat beragama lain pun akan cenderung memilih produk-produk yang telah memiliki kejelasan halal,karena lebih terjamin ketika akan mengkonsumsinya. Akibat kecenderungan perilaku tersebutlah industri halal saat ini tidak hanya terbatas pada makanan dan minuman saja, melainkan pariwisata, fashion, dan sebagainya. Tujuan penelitian ini untuk mengetahui kondisi perkembangan industri halal di Indonesia saat ini.Penelitian ini akan menggunakan metode kualitatif yang ditunjang oleh data-data relevan yang telah didapatkan dari berbagai laman resmi ataupun lamanterpercaya lainnya. Hasil penelitian menunjukkan ekonomi dan keuangan syariah Indonesia berhasil menempati posisi ke-4 dunia dengan menjadi konsumenterbesar pada sektor konsumsi produk halal. Melihat semakin meningkatnya kontribusi dan pangsa pasar industri halal di Indonesia, pemerintah pun melihathal ini sebagai peluang bagi perekonomian bangsa. Saat ini pemerintah senantiasa berusaha mendukung industri halal di Indonesia dengan berbagai upaya, salah satunya melalui penerapan kebijakan sertifikasi halal.
Analisis Peran Asuransi Syariah Pada Perekonomian Indonesia
Authors: H. Ahmad Luthfi H. Abdul Jalil, Rigita Febriyanti,
Published: October 2024

Asuransi syariah merupakan salah satu lembaga asuransi yang menerapkan sistem syariat Islam dalam menjalankan mekanismenya, dengan akad untuk saling tolong menolong antar sesama nasabah asuransi syariah bila ada yang mendapatkan suatu musibah. Penelitian ini menggunakan metode penelitian kualitatif untuk mengetahui peran asuransi syariah bagi perekonomia masyarakat Indonesia dan untuk mengetahui lebih luas mekanisme asuransi syariah serta proses pengelolaan dana, peran asuransi syariah terhadap masyarakat yang bergabung pada lembaga asuransi syariah antara lain dapat mengalihkan resiko finansial yang disebabkan oleh kejadian atau musibah yang tak terduga sebagai proteksi untuk diri sendiri maupun keluarga, agar terbiasa menyisihkan dana dan mengelola uang untuk kebutuhan di masa mendatang, pada masyarakat asuransi syariah adalah subsidi silang antar satu individu dengan individu yang lainnya, karena uang yang dibayarkan di asuransi syariah sebagian disetorkan untuk biaya tabarru'
PENGARUH HARGA DAN MEREK SEBAGAI PEMBANDING TERHADAP KEPUTUSAN PEMBELIAN ANTARA MINYAK GORENG KEMASAN ATAU CURAH DITENGAH TINGGINYA HARGA MINYAK GORENG DI KUALA TUNGKAL
Authors: Melisa Ayu Wandira Ahmad Luthfi,
Published: October 2024

Minyak goreng ialah satu dari berbagai bentuk produk turunan berbahan minyak dari nabati dan begitu diperlukann dalam keseharian. Baru-baru ini terjadi lonjakan harga minyak yang gila-gilaan di Indonesia. Tepatnya dimulai pada awal Januari 2022. Saat diberlakukan harga HET minyak menjadi langka. Namun saat harga kembali naik jumlah minyak beredar menjadi melimpah. Oleh karena itu peneliti menarik sebuah judul “Pengaruh Harga Dan Merek Sebagai Pembanding Terhadap Keputusan Pembelian Antara Minyak Goreng Kemasan Atau Curah Ditengah Tingginya Harga Minyak Goreng Di Kuala Tungkal” untuk mengamati perilaku masyarakat dalam memutuskan memilih minyak kemasan atau curah disaat nilai minyak sedang tinggi. Metode yang dipergunakan di penelitian ini yaitu metode kuantitatif. Jenis dari data yang dipergunakan meliputi penelitian sekali ini yaitu data primer dan sekunder. Sumber dari data primer didapatkan melalui menyebarkan angket online kepada masyarakat umum untuk kemudian jawaban responden dioleh menggunakan aplikasi statistik PLS-SEM. Sedangkan data sekunder berdasar kepada jurnal-jurnal terdahulu. Menurut penelitian yang dilaksanakan disimpulkan dengan indikator harga minyak goreng curah mempunyai hubungan kepada keputusan pembelian, Indikator harga minyak goreng kemasan berpengaruh untuk keputusan pembelian, kemudian indikator merek minyak goreng curah tidak terindikasi berhubungan terhadap keputusan pembelian, serta indikator merek minyak goreng kemasan tidak terindikasi punya hubungan pada keputusan pembelian.
SISTEM OPERASIONAL SYARIAH (BAGI HASIL / PROFIT SHARING)
Authors: Syuhada,Serlina Azizah Rahmawati, Eka Rahma, Djahratun,
Published: October 2024

Tujuan penulisan artikel ini salah satunya adalah untuk dapat mengetahui akan Sistem Operasional Syariah (Bagi Hasil / Profit Sharing). Sistem bagi hasil yang diterapkan di dalam perbankan syari’ah terbagi kepada dua sistem, yaitu; pertama. Profit Sharing yaitu sistem bagi hasil yang didasarkan pada hasil bersih dari pendapatan yang diterima atas kerjasama usaha, setelah dilakukan pengurangan-pengurangan atas beban biaya selama proses usaha tersebut. Kedua. Revenue Sharing adalah sistem bagi hasil yang didasarkan kepada total seluruh pendapatan yang diterima sebelum dikurangi dengan biaya-biaya yang telah dikeluarkan untuk memperoleh pendapatan tersebut. Penelitian ini menggunakan metode kajian kepustakaan (library research). Dari hasil penelitian didapatkan dalam perbankan syari’ah Indonesia sistem bagi hasil yang diberlakukan adalah sistem bagi hasil dengan berlandaskan pada sistem revenue sharing. Bank syari’ah dapat berperan sebagai pengelola maupun sebagai pemilik dana, ketika bank berperan sebagai pengelola maka biaya tersebut akan ditanggung oleh bank, begitu pula sebaliknya jika bank berperan sebagai pemilik dana akan membebankan biaya tersebut pada pihak nasabah pengelola dana.
ZAKAT, INFAK DAN SHADAQAH SEBAGAI KETAATAN KEPADA ALLAH DAN RASULULLAH S.A.W (Studi Kasus di Desa Parit Pudin)
Authors: Hidayat Suhidra , Apriyani Mirna , Said M.
Published: October 2024

Zakat, Infak dan Shadaqah merupakan hal yang sudah tidak asing lagi dikalangan umat muslim. Zakat, Infak dan Shadaqah juga sudah dikenal dan dilaksanakan oleh umat muslim sejak lama. Berbicara tentang zakat selalu tidak luput juga berbicara tentang Infak dan Shadaqah. Zakat merupakan salah satu insturmental dalam mengentas kemiskinan, karena masih banyak lagi sumber dana yang bisa dikumpulkan seperti infak, shadaqah, akaf, wasiat, hibah serta sejenisnya. Sumber-sumber dana tersebut merupakan pranata keagamaan yang memiliki kaitan secara fungsional dengan upaya pemecahan masalah kemiskinan dan kepincangan sosial. Dana yang terkumpul akan merupakan potensi besar yang dapat memberdayakan puluhan juta rakyat miskin di Indonesia yang kurang dilindungi oleh sistem jaminan sosial yang terprogram dengan baik. Infak berbeda dengan zakat, infak merupakan pemberian yang tidak ada nisabnya sedangkan zakat sebaliknya. Besar kecilnya sangat tergantung kepada keuangan dan keikhlasan dalam member, yang terpenting adalah hak orang lain yang ada dalam harta kita yang sudah dikeluarkan. Sedangkan untuk shadaqah sendiri ialah menurut terminologi syariat, pengertian shadaqah sama dengan pengertian infak, termasuk juga hukum dan ketentuan-ketentuannya. Shadaqah diartikan sebagai sebuah pemberian seseorang secara ikhlas kepada orang yang berhak menerima yang diiringi juga oleh pahala dari Allah.
STATUS KEPEMILIKAN MENURUT EKONOMI SYARIAH
Authors: Jalil Abd
Published: October 2024

Kepemilikan suatu benda dapat dilakukan dengan berbagai cara akan tetapi ada tata cara yang mesti dilakukan untuk memiliki benda tersebut secara penuh Milk Tamm, baik dengan pemberian, hadiah, shadaqah dan lain sebagainya, akan tetapi yang terpenting adalah dengan cara akad yang dilakukan kedua belah pihak, bias juga dengan cara jalan warisan ketika pemilik benda itu meninggal atau dengan cara jalan wasiat.
ANALISIS STRATEGI PEMASARAN PADA PRODUK CEMILAN “KAK ROS” SUNGAI SAREN DALAM PENINGKATAN KUALITAS DAN PERSAINGAN USAHA
Authors: Dhita Wijayanti Azizah Rahmawati,
Published: October 2024

Dalam merintis sebuah bisnis, salah satu hal penting yang harus diperhatikan dalam menjalankannya adalah strategi pemasaran. Berkembang bisnis semakin banyak persaingan maka strategi pemasaran harus dilakukan dengan baik agar hasilnya sebanding dengan rencana dan tidak kalah di pasar. Karena itu perlu dilakukan  penelitian mengenai strategi pemasaran ditinjau  dari segi ekonomi syariah. Dengan latar belakang tersebut pebisnis perlu mengamati strategi pemasaran yang dijalankan supaya dapat bersaing dengan pelaku bisnis lainnya sesuai ketentuan prinsip ekonomi syariah. Permasalahan yang diambil pada penelitian ini yaitu strategi pemasaran pada produk cemilan “Kak Ros” dalam peningkatan kualitas dan persaingan usaha umkm. Dengan tujuan untuk mengetahui strategi pemasaran  yang digunakan cemilan kak ros dengan kesesuaian prinsip ekonomi syariah. Data dalam penelitian ini diperoleh dari hasil observasi, wawancara, dan dokumentasi. Adapun hasil dari penelitian yang diperoleh dari usaha cemilan “Kak Ros” menggunakan strategi pemasaran yang biasa disebut marketing mix dengan meninjau pada kualitas produk, harga, promosi, dan tempat. Dalam penerapkan strategi pemasarannya usaha Cemilan “Kak Ros” berdasarkan pada prinsip ekonomi syariah yaitu siddiq, fathonah, amanah, dan tabligh.
PENDAMPINGAN PEMBUATAN CELENGAN MENABUNG DINI UNTUK BEKAL MASA DEPAN
Authors: Arif M Syaikhul , Said M. , Apriyani Mirna , Hanifa Siti
Published: October 2024

Pembiasaan menabung sejak dini perlu diupayakan dengan cara pengabdian masyarakat oleh perguruan tinggi dengan cara sosialisasi dan praktek pembuatan celengan/ tabungan dan pemberian rewead, dan survey hasil pelaksanaan pengabdian tersebut untuk melihat tingkat keberhasilannya.
MENABUNG DI BANK KONVENSIONAL DAN DI BANK SYARIAH DALAM PANDANGAN EKONOMI ISLAM
Authors: Bahrul ulum Suprihatin Lestari,
Published: October 2024

Investasi adalah komitmen atas kegiatan yang dilakukan oleh seseorang atau badan hukum, untuk menyisihkan sebagian pendapatannya agar dapat digunakan untuk melakukan suatu usaha dengan harapan pada suatu waktu tertentu akan mendapatkan hasil (keuntungan).Maraknya penipuan investasi, dan ketidakjelasan hasil keuntungan yang didapat apakah diperoleh dari hasil keuntungan investasi yang halal atau tidaknya, mengharuskan masyarakat untuk lebih selektifdalam menginvestasikan hartanya. Artikel ini mendiskusikan konsep investasi dan investasi tabungan di Bank Syariah dengan prespektif hukum ekonomi syariah. Perbankan syariah melakukan kegiatan usaha penghimpunan dana, berdasarkan PrinsipSyariah. Prinsip muamalah sesungguhnya terimplementasi dalam hukum perbankan Indonesia, sebagaimana ditemukan dalam beberapa pasal dalam undang-undang perbankan, tetapi tidak berarti diimplementasikan. Artinya, ketika undang-undang disusun kuat dugaan tidak membawa pesan khusus untuk memasukkan prinsip-prinsip muamalah yang terimplementasi dalam undang-undang perbankan karena prinsip-prinsip muamalah bersifat unversal yang dijunjung tinggi oleh nilai-nilai kemanusiaan.
ANCAMAN KRISIS EKONOMI DUNIA AKIBAT DAMPAK PERUBAHAN IKLIM DAN PEMANASAN GLOBAL
Authors: Nur Indah Suhidra, Aulia rahma,
Published: October 2024

This study aims to determine the effects of illegal changes and global warming on the world economic crisis. This type of research is an analysis of qualitative data by data in the form of secondary data obtained from the library study by collecting data from the various books, news articles and economic journals and other agencies related to research conducted. From the results of this study it is concluded that natural disasters caused by global warming can also interfere with the global supply chain, slowing international trade, and increasing logistics costs. The impact of climate change in the economic sector can be seen from the frequency and intensity of natural disasters such as floods, droughts, storms, and forest fires that cause livelihoods, as well as high recovery and reconstruction fees.
DASAR HUKUM DAN METODOLOGI PENGEMBANGAN EKONOMI SYARIAH
Authors: Arif M. Syaikhul
Published: October 2024

Sumber hukum ekonomi syariah merupakan dasar-dasar yang digunakan sebagai acuan dalam mengembangkan produk hukum ekonomi syariah. Kaidah-kaidah dan hukum ekonomi syariah didasarkan pada sumber hukum yang telah disepakati oleh para ulama dan umat Islam. Sumber hukum Islam terdiri dari Al-Qur'an, as-Sunnah, Ijma', dan Qiyas, meskipun ada variasi pendapat mengenai metode ini. Sumber hukum ekonomi syariah terdiri dari dua kategori, yaitu sumber primer (seperti Al-Qur'an, Sunah Nabi, Ijma', dan Qiyas) dan sumber sekunder (seperti istihsan, istishab, mashalih al-mursalah, al-'urf, dan lainnya). Dalam bidang ekonomi syariah, Al-Qur'an menjadi sumber utama yang mengatur kaidah-kaidah dasar yang bersifat tetap. Metode penelitian merupakan cara ilmiah untuk memperoleh data dengan tujuan khusus, dan dapat diklasifikasikan berdasarkan tujuan, tingkat kealamiahan, dan sifatnya, seperti penelitian dasar, terapan, pengembangan, eksperimen, survei, eksploratif, deskriptif, dan eksplanatoris. Penelitian menjadi penting dalam pengembangan ilmu pengetahuan karena membantu dalam menemukan informasi baru, latar belakang masalah, dan pemecahan masalah yang bermanfaat bagi kehidupan manusia serta membentuk teori baru.
NILAI FILOSOFIS TRANSAKSI DALAM EKONOMI SYARIAH
Authors: Jalil Abd
Published: October 2024

Kepercayaan konsumen mendapat perhatian cukup besar dari para pelaku bisnis. Dalam transaksi, embrio kepercayaan dimulai dengan pelaksanaan transaksi atau akad yang sesuai dengan Al-Qur'an dan as-Sunnah. Akad adalah salah satu langkah awal mula terjadinya suatu transaksi yang ketika dijalani dengan fair, akan menghasilkan benefit yang halal dan berkah. Segala pelaksanaan transaksi bertujuan untuk meniadakan angka penipuan, persengketaan, ataupun segala macam dampak negatif yang timbul dari keinginan menguasai suatu barang atau memiliki manfaatnya Adapun tujuan akad adalah untuk melahirkan suatu akibat hukum, atau lebih tegasnya lagi tujuan akad adalah maksud bersama yang dituju dan hendak diwujudkan oleh para pihak melalui pembuatan akad. Secara garis besar, pemetaan akad dalam hukum Islam dapat diklasifikasikan dalam tiga bentuk akad berdasarkan kegiatan usaha, yaitu: akad pertukaran, akad kerja sama, dan akad pemberian kepercayaan.
TANGGUNG JAWAB DAN HAK NAZHIR WAKAF
Authors: Arif Mhd
Published: October 2024

Seorang Nazir Wakaf merupakan individu atau kelompok yang bertanggung jawab atas pengelolaan, pemeliharaan, dan distribusi manfaat dari harta wakaf. Posisi ini memiliki peran yang sangat penting dalam menjaga keberlanjutan serta memastikan bahwa tujuan wakaf, baik yang bersifat amal sosial maupun keagamaan, dapat tercapai sesuai dengan prinsip-prinsip Islam. Tanggung jawab Nazir Wakaf mencakup penerapan prinsip-prinsip etika Islam dalam pengelolaan harta dan distribusi manfaat. Seorang Nazir Wakaf diharapkan menjalankan tugasnya dengan itikad baik dan penuh tanggung jawab untuk mewujudkan manfaat maksimal dari harta wakaf sesuai dengan tujuan dan nilai-nilai Islam.
Symbolism In The Mosques of Mimar Sinan: Inscriptions, Meanings, and Architectural Order
Authors: Şimşek Cemile Feyzan , Peker Ali Uzay , Şener Sinan Mert
Published: October 2024

Architectural spaces not only consist of structural elements but also bear traces from the period in which they were built. These traces can be religion, culture, economy, power, technology, abstract concepts, or symbols. Worship places, in particular, contain diverse symbols and indicators due to their mission. Mosques specific to the Islamic religion also have various symbolic elements besides their original architectural features. It is seen in history that these elements are included in mosque architecture with abstract ornaments and calligraphy. In the mosques of Mimar Sinan’s period, the inscriptions mainly consist of Qur’ān verses. These verses are placed on many architectural elements, starting from the dome. The study aims to systematically question and reveal the relationship between these verses and the architectural elements where they are placed using the semiotic method. Five mosques, the richest in terms of the epigraphy program, were selected as samples for the study. All the inscriptions in the mosques were identified on-site, and their accuracy was ensured by comparing them with sources related to the period. In this study, the symbolism of the inscriptions in Mimar Sinan’s mosques, which has not been revealed before, is presented uniquely for each architectural element by reading them through the inscriptions and structural elements.
Understanding the Impact of Cultural Factors on Healthcare Outcomes: A Data-Driven Comparison of US and Nigerian Healthcare Systems
Authors: Okeme Arome Bala Kacy , Godwins Ojamalia Priscilla , Gusen Mashak Joseph , Gbaa Terry , Pam-Tok Alice Onyeche , Uwe Victor Edet
Published: October 2024

This review explores the critical role cultural factors play in shaping healthcare outcomes, with a comparative focus on the United States and Nigerian healthcare systems. Cultural competence in healthcare is increasingly recognized as essential for improving patient care and reducing health disparities. This study aims to provide a comprehensive understanding of how cultural norms, beliefs, and practices influence healthcare delivery and outcomes in these two distinct contexts. In the United States, the diversity of the population presents unique challenges and opportunities for healthcare providers to deliver culturally competent care. The review examines the impact of multiculturalism and diversity on healthcare outcomes, supported by case studies and data analysis. In contrast, Nigeria’s healthcare system is influenced by traditional beliefs and practices, which significantly affect patient behavior and health outcomes. This study delves into the structure and function of the Nigerian healthcare system, highlighting the role of cultural factors in healthcare delivery. Through a data-driven comparative analysis, the review identifies key similarities and differences in the impact of cultural factors on healthcare outcomes in both countries. It provides insights into successful interventions and programs that have improved cultural competence in healthcare. The findings offer valuable policy implications, suggesting strategies for policymakers and healthcare providers to enhance cultural competence and ultimately improve healthcare outcomes. The review concludes with recommendations for future research, addressing gaps in current knowledge and proposing areas for further investigation. By understanding and addressing the cultural factors that influence healthcare outcomes, this study aims to contribute to the development of more effective, culturally sensitive healthcare systems in both the United States and Nigeria.
Development of Small Molecule Positron Emission Tomography Tracers Targeting Mutated Epidermal Growth Factor Receptor Kinase
Authors:   , Högnäsbacka Antonia Alice
Published: October 2024

This thesis aims to drive the research on identifying NSCLC mutations in vivo using small molecule tyrosine kinase inhibitor (TKI) PET tracers to facilitate targeted drug therapy development, focusing mainly on EGFR mutations. An EGFR PET tracer could be used, e.g., for disease progression monitoring and stratification for personalized therapy or as a tool to develop new inhibitors. Chapter 2 reflects on the history of EGFR inhibitor development and how the field has evolved as it has. It discusses the key findings that drove the targeted (small molecule) drug therapy research forward, what has been learned from EGFR-targeting PET, and why certain evaluation methods became standard practice.

While the first-generation TKI PET tracer [11C]erlotinib has been demonstrated to target primary EGFR mutations, it has been indicated to be unable to differentiate between treatment-sensitive primary Del19 mutations and treatment-resistant secondary T790M mutations in vivo [14]. Osimertinib, a third-generation TKI, has been shown to be effective in the clinical treatment of the T790M resistance mutation [15]. Chapter 3 describes the synthesis of two osimertinib 11C-labeled isotopologs. The study aimed to evaluate the potential of 11C-labeled osimertinib to be used as a tracer for PET imaging tumors bearing the EGFR T790M resistance mutation.

As many receptor kinases in NSCLC are closely related, a drug that blocks the function of a specific section of one kinase might show affinity for another structurally related kinase. These drugs can be considered multi-kinase inhibitors. Chapter 4 describes the 11C-labeling of an ALK inhibitor, brigatinib, which was also proposed to inhibit EGFR [16]. This study evaluated the suitability of [methylpiperazine-11C]brigatinib as a PET tracer for EML4-ALK and EGFR mutational status assessment in NSCLC xenografted mice.
As the disease progresses, a tertiary resistance mutation in the form of C797S has been observed following treatment with osimertinib [17]. Due to the constant resistance mutation development, alternative ways of inhibiting the function of mutated receptors are constantly being researched. One such alternative inhibitor is EAI045. In Chapter 5, EAI045 was radiolabeled with carbon-11 and tritium to gain further knowledge and understanding of the tumor-targeting potential of this alternative inhibition pathway.
Model-Based Optimization in Home Healthcare
Authors:   , Clapper Yoram
Published: October 2024

Home healthcare delivery requires careful planning to ensure efficient use of resources and client satisfaction. This dissertation explores various algorithmic and analytical methods to determine and utilize caregiver capacity efficiently to meet client demand. The models presented are inspired by real-world practices and formulated as optimization problems that balance operational efficiency, client-centered care, and manageable workloads for caregivers.
Branchless Banking: The Role of Fintech Technologies and the Internet of Things (IoT) in the Disruption of the Traditional Banking Model
Authors: Cobos Gutierrez Carlos Eduardo
Published: October 2024

Branchless banking has emerged as a revolutionary model driven by the adoption of Fintech and Internet of Things (IoT) technologies. This systematic review examines how these technologies are transforming traditional banking business models, focusing on customer experience, operational efficiency, and regulatory challenges. Fifteen studies published between 2018 and 2024 were reviewed, highlighting the impact of Fintech and IoT on banking digitalization, particularly in cybersecurity, sustainability, and financial inclusion. The findings suggest that these emerging technologies will continue to be key to the evolution of the banking sector, although challenges remain, especially in emerging and rural markets.
PCLD COMO MECANISMO DE GERENCIAMENTO DE RESULTADOS CONTÁBEIS EM COOPERATIVAS DE CRÉDITO NO BRASIL DURANTE OS ANOS DE 2018 A 2020
Authors: Kammer Eulalia , Kos Sonia Raifur
Published: October 2024

O presente estudo teve como objetivo identificar se as cooperativas de crédito do Brasil utilizam a discricionaridade da PCLD (Provisão para Créditos de Liquidação Duvidosa) como mecanismo de gerenciamento de resultados contábeis (GRC). A discricionaridade na constituição da PCLD é a parcela acima do limite regulamentar de constituição definido pela Resolução CMN nº 2.682/99. Os testes foram realizados por meio do modelo MQO (Mínimos Quadrados Ordinários), com informações semestrais de 2018 a 2020, em 50 cooperativas de créditos aleatórias e revelaram a associação positiva e relevante entre a parcela discricionária da PCLD e o lucro líquido ajustado – antes da adição da parcela discricionária. Esses resultados confirmaram a hipótese da pesquisa de que há discricionariedade na formação de PCLD como mecanismo de gerenciamento de resultados, ou seja, em momentos em que os resultados são relevantes, as cooperativas criam uma espécie de “colchão” de PCLD, que é revertido em períodos em que não pesquisa contribuem para o avanço da literatura de gerenciamento de resultados em instituições financeiras, em especial as cooperativas de crédito, tendo em vista que grande parte dos estudos existentes são voltados a instituições financeiras com fins lucrativos.
PREVALÊNCIA E FATORES ASSOCIADOS À HIPERTENSÃO ARTERIAL SISTÊMICA EM ADULTOS
Authors: Gomes Ana Alice Carvalho , Nascimento Elaine Cristina do , Padilha Luana Lopes , Sodré Samiria de Jesus Lopes Santos , Melo Naruna Aritana Costa , Cavalcante Deivyd Vieira Silva , Serra Renata Kariny Correia , Cavalcante Lilian Fernanda Pereira
Published: October 2024

A Hipertensão Arterial Sistêmica (HAS) é uma doença crônica não transmissível multifatorial com altos índices de mortalidade no Brasil e no mundo. O estilo de vida inadequado tem sido apontado como um dos principais fatores para seu surgimento. Este estudo teve como objetivo associar a hipertensão arterial sistêmica a fatores socioeconômicos e comportamentais em adultos residentes na capital São Luís, Maranhão. Trata-se de um estudo analítico, transversal e de base populacional, realizado por meio de dados secundários coletados do sistema de vigilância de fatores de risco para doenças crônicas por inquérito telefônico, Vigitel, no ano de 2019. As variáveis categóricas foram descritas por frequências relativas, absolutas e p-valores. Foram avaliados 2.065 participantes, e a prevalência de hipertensão arterial sistêmica foi de 31,3% e dos participantes 65,8% eram do sexo feminino . A hipertensão apresentou associação estatística significativa com escolaridade (p<0,0001), idade (p<0,001), estado civil (p<0,0001), sexo (p<0,0001), raça (p<0,0001), consumo abusivo de álcool (p<0,0001), consumo de tabaco (p<0,0001), tempo de tela (p=0,008), excesso de peso (p<0,001), uso de cigarro eletrônico (p<0,014) e consumo de alimentos industrializados (p<0,0001). Estes resultados sugerem a necessidade de estratégias de prevenção e controle da hipertensão direcionadas aos grupos populacionais e fatores associados identificados. Assim, a identificação de variáveis associadas à hipertensão é uma importante ferramenta para o manejo da doença em diversos níveis de assistência e para o desenvolvimento de ações eficazes em saúde pública.
The Influence of Tax Understanding and Income Tax Incentives on MSME Tax Compliance, Moderated by Tax Digitalization
Authors: Putri Helmalia , Din Muhammad , Furqan Andi Chairil , Tanra Andi Ainil Mufidah
Published: October 2024

This study investigates how tax knowledge and income tax incentives affect tax compliance among MSMEs, with tax digitalization functioning as a moderating variable. MSMEs are vital to Indonesia's economy, yet achieving tax compliance in this sector poses significant challenges, especially in Palu, which has been heavily impacted by the 2018 natural disaster and the COVID-19 pandemic. In response to these difficulties, the government launched several measures, including Regulation No. 44 of 2020, which offers tax incentives for businesses affected by the pandemic. However, as of May 2020, the adoption of these incentives among MSME operators was notably low (D. Setiawan, 2018). This situation led researchers to explore whether MSMEs in Palu have effectively taken advantage of these income tax incentives. The research utilized a quantitative methodology, employing a Likert scale to measure the impact of the independent variables on the dependent variable. The population for the study comprised MSMEs registered with the Department of Cooperatives, MSMEs, and Labor in Palu, with purposive sampling used to select respondents based on specific criteria. Data collection was conducted manually using questionnaires, and the analysis was performed using WarpPLS 7.0. The findings indicated that tax knowledge significantly and positively influences MSME tax compliance, and income tax incentives also demonstrate a substantial positive effect. Although tax digitalization does not significantly moderate the relationship between tax knowledge and compliance, it does play a moderating role in the effect of income tax incentives on compliance.
"Kom ihåg att ALDRIG skämmas!"
Authors: Wanström Sofia
Published: October 2024

Shame and guilt have followed victims of sexual assault for centuries. However, since the 70s, feminist work has started to change the view of who is responsible for assault. Within Dammen brister, the Finland-Swedish MeToo-campaign, the witnesses often mention shame: to explain an (in)action or the process of recovery, or as a common enemy for victims to overthrow. I argue that the witnesses utilize a specific feminist shame discourse, according to which it is the perpetrators and not the victims who should feel ashamed, while recognizing that shame is still a common result of sexual assault and may affect victims in various ways. A shift of the responsibility for sexual violence from the perpetrator to the victim is undoubtedly a victory for feminism. Still, it is worth to be cautious not to make shame a self-evident outcome of rape, for that could restrict the victim’s right to her own experience and become a necessity for her trustworthiness.
Соціальний захист військовослужбовців та умови проходження ними служби: питання співвідношення
Authors: Ковальський В. В.
Published: October 2024

Метою цього дослідження є визначення поняття соціального захисту військовослужбовців та встановити його співвідношення з умовами проходження служби військовослужбовцями. Необхідність дослідження цих питань пов’язана, головним чином, із розбіжностями у законодавстві та науковій думці щодо охоплення соціальним захистом військовослужбовців не лише тих заходів, які забезпечують належну якість життя та додаткові блага військовослужбовцям після їх звільнення зі служби ) у зв’язку зі взяттям ними на себе соціальних ризиків особливого характеру, а й заходів матеріального, соціально-побутового та медичного забезпечення військовослужбовців, які є частиною їх статусу під час проходження ними служби. Основними методами дослідження стали нормативно-догматичний метод та методи аналізу й синтезу. За підсумками дослідження визначено, що соціальний захист військовослужбовців є системою організаційно-правових та економічних заходів, які закріплені положеннями законодавства, здійснюються за рахунок бюджетних коштів та спрямовані на забезпечення військовослужбовцям та особам, які звільнились з військової служби, спроможності самостійно задовольняти їх потреби на особливому рівні, який відповідає їх внеску у зміцнення стану національної безпеки, економічного добробуту й утвердження прав людини та слугує соціально-економічною компенсацією за обмеження та ризики, пов’язані з військовою службою. У світлі того, обґрунтований висновок про те, що заходи соціального захисту військовослужбовців не охоплюють умови проходження служби військовослужбовцями (зокрема, питання їх матеріального, соціально-побутового та медичного забезпечення), оскільки встановлення порядку проходження військової служби спрямоване на визначення її особливостей повсякденного життя і службової діяльності військовослужбовців, а не безпосередньо на соціально-економічну компенсацію військовослужбовцям за обмеження та ризики, пов’язані з військовою службою.
Exploring Gender Discrimination Faced by Women in Indian Sports
Authors: Vasishat Dr. Anjali
Published: October 2024

In today's world, we often hear discussions about equality between men and women. However, when it comes to sports, there's a noticeable silence surrounding this issue. Women and girls participate in sports at much lower rates compared to men. In comparison to men's sports, women's sports events receive substantially less media coverage. This gender gap in sports is underpinned by a numerous of barriers, which can be categorized as 'practical,' 'personal,' and 'social and cultural.' Practical barriers encompass logistical challenges such as access to facilities and resources, while personal barriers may include factors like confidence and societal expectations. Social and cultural barriers manifest in stereotypes and biases that limit opportunities for women in sports. Moreover, women face specific challenges within the sports arena, including unequal pay, a lack of female coaches and mentors, biased award systems, and inadequate familial support. These obstacles not only hinder women's participation but also obstruct their progression and success within the sporting domain. This paper aims to shed light on these challenges and offer practical solutions to enhance women's participation in sports. Encouraging girls' and women's participation in sports is crucial not only for promoting gender equality and women's empowerment but also for broader societal development and social change. Methodology: Methodology involves comprehensive data collection from secondary sources such as websites, articles, newspapers, and books. Through analysis and synthesis of this data, this paper, endeavor to provide valuable insights and policy suggestions to address the multifaceted barriers faced by women in sports. Keywords: Gender Equality, Sports Participation, Barriers, Women's Empowerment, Social Change.
Loan Approval Prediction Using Machine Learning
Authors:   Nehru college of management, Coimbatore, Tamilnadu, India, Sengaliappan Dr.M , Sangaiah P ,   Nehru college of management, Coimbatore, Tamilnadu, India
Published: October 2024

Loan approval prediction using machine learning (ML) leverages data-driven techniques to assess the likelihood of a loan applicant being granted approval. Traditional lending models often rely on manual reviews or rigid rules, which can overlook patterns that modern machine learning algorithms can detect. By analysing historical data, such as credit scores, income levels, employment status, loan amounts, and past repayment behaviours, ML models can identify the key factors that influence approval decisions. Common algorithms used for this task include logistic regression, decision trees, random forests, and gradient boosting machines, each providing varying levels of accuracy and interpretability. The application of ML in loan approval prediction improves both efficiency and fairness in the decision-making process. These models can process vast amounts of data quickly, reducing approval times, while also minimizing human biases. Furthermore, ML can enable institutions to continuously adapt their decision criteria based on new data trends, providing a more dynamic and responsive approach to loan assessment. Keywords: logistic regression, decision trees, random forests, SVM
Pra-Pelaksana Verifikasi Data pada Program Bantuan Kursi Roda Disabilitas Terindeks DTKS di Kecamatan Medan Helvetia
Authors: Fanny Pratiwi  , Fajar Utama Ritonga
Published: October 2024

A physical, intellectual or mental disability that prevents a person from carrying out activities or interacting with their environment independently is known as a disability. The problems that people with disabilities often face in Indonesia, especially people with low economic conditions, include lack of access to information about the importance of rehabilitation and lack of public facilities that make it easier for people with disabilities to carry out daily activities. Disabled people need wheelchair assistive devices to improve their accessibility and mobility. So there is a goal of this community service as an important effort to help recipients of assistance so they can be verified and receive the assistance. This activity is accompanied by Social Workers from the Medan City Social Service for the Wheelchair Assistance Program which requires verification and validity of data so that the Wheelchair Assistance Program for Disabled People is indexed. in Medan City's Integrated Social Data (DTKS) right on target. This article uses qualitative methods with literature studies and field activities. Pre-implementation of this program involves the stages of identification, application submission, and data verification. The results obtained were that of the 3 disabilities recorded, there were only 2 disabilities registered by DTKS in Medan Helvetia District which were verified and valid from data on requests for wheelchair assistance. This Community Service output also produces information regarding disability assistance which must be indexed in the Integrated Social Data (DTKS) in Medan City.
Pengembangan Usaha Kerang Kering sebagai Produk Unggulan Masyarakat di Desa Suka Maju Kabupaten Batubara
Authors: Adil Arifin  , Indra Fauzan  , Suci Rahmadani  , Fajar Utama Ritonga
Published: October 2024

Mapping of local economic potential needs to be carried out to determine the potential that exists in the area and the human resources it has. Batu Bara Regency is one of the districts in North Sumatra which has potential in the marine sector, such as fish, shrimp, crab, shellfish, and so on. Various marine-based business activities have great potential to be developed in this region. One form of this business is the dried shellfish business in Suka Maju Village, Batu Bara Regency. This dry shellfish business is carried out by around 12 community groups. However, it is very unfortunate, there are several obstacles faced by the community which are the reason why the dried shellfish business has not developed. Among them is that there is no legal entity that protects the business, so the price is according to the agent's request. Second, there is no product packaging, and the business group's lack of knowledge in product marketing. The results of this service are activities in the form of training on product packaging, product marketing, and managing legal entities for businesses.
Pengembangan Homestay Manggis untuk Mendukung Desa Wisata Angsana, Desa Setu, Kecamatan Jasinga, Kabupaten Bogor
Authors: Daniel Jehovah  , Budi Setiawan  , Brandon Fandra  , Benjiro Lepar  , Darren Owen
Published: October 2024

The development of homestays in Angsana Tourism Village, Setu Village, Jasinga District, Bogor Regency, is a strategic initiative aimed at supporting community-based tourism with a focus on enhancing the quality of services and homestay facilities. This program aims to strengthen the appeal of the tourist destination by improving the comfort of accommodations offered to visitors, while also empowering the local community by increasing economic welfare. The methods used in this program include field observations, intensive dialogue with homestay owners, and the implementation of a work program that involves improving the physical infrastructure of homestays, such as room cleaning, installing mosquito nets, ceiling repairs, curtain installation, and rearranging furniture. Additionally, homestay management training and the introduction of digital marketing strategies were provided to expand promotional reach and attract more tourists. The results of this program show a significant improvement in the comfort and aesthetics of the homestays, positively impacting the visitor experience. Thus, this program is expected to support sustainable tourism development in Angsana Tourism Village while enhancing the welfare of the local community through increased tourist visits.
Sosialisasi Penggunaan Kantong Belanja Ramah Lingkungan (Reusable) untuk Meminimalisir Sampah Plastik pada Ibu-Ibu TP-PKK di Kelurahan Bugel Kota Tangerang
Authors: Humairoh Humairoh , Atik Atikah  , Septiano Cahyo Bintoro
Published: October 2024

Community Service Program in the form of educational activities to minimize plastic waste by using environmentally friendly shopping bags among TP-PKK mothers to create an environment free from the use of plastic shopping bags in Bugel Village, Karawaci District, Tangerang City. This needs to be considered more seriously because using plastic bags excessively can create waste that is difficult to decompose on its own, therefore education is intended to invite the Bugel Village community, especially TP-PKK mothers, to reduce plastic bags as shopping containers. The method used is to hold socialization and education activities at a seminar on the impact of waste on the environment for TP-PKK mothers in Bugel Village, Tangerang District, Tangerang City. This socialization was held on Sunday, August 16, 2024 at the NU Branch Hall, Bugel Village, Tangerang District, Tangerang City. By organizing educational programs and awareness campaigns about the use of reusable environmentally friendly shopping bags, we can empower the Bugel Village community to take more sustainable actions, and this initiative will not only help reduce plastic waste but will also improve environmental quality and public health. Through education and active participation, TP-PKK mothers in Bugel Village can build a cleaner community that cares more about the environment, because this effort requires support and active participation from the entire Bugel Village community.
2018 Pyeongchang Winter Olympics as Peace Instrument of South and North Korea
Authors: Mulyaman Darynaufal , Ismail Achmad , Tambunan Issuwari , Manurung Engelita Evelin , Pangasah Gabriella A.
Published: October 2024

There are various ways for countries to fulfill their national interests, one of which is through diplomacy, especially in the field of sports. That's what happened at the 2018 Pyeongchang Winter Olympics. This sporting event was used as a way to find peace between South Korea and North Korea. This research seeks to explain how sport can act as an instrument to achieve peace. This research also aims to provide a specific picture of how sport can have a positive impact on countries in conflict, in this context South Korea and North Korea. Sports support for development and peace can be achieved because sport provides a catalyst for non-military diplomacy. Therefore, sport is seen and considered as an important social link in bilateral and multilateral relations. This research is qualitative research with a case study method that uses data collection and analysis through literature study. Data was collected and analyzed using a liberalism perspective with a functionalism approach and the concept of sports diplomacy. The result is that the success of the 2018 Pyeongchang Winter Olympics has resulted in increased positive interaction between South Korea and North Korea, especially in sports partnerships.
Analisis Perbandingan Pengaruh Sistem Lingkungan terhadap Residen di IPWL BUKIT DOA melalui Perspektif Teori Sistem
Authors: Anita Maisaroh  , Yolanda Oktari Br Bangun  , Rachel Yohana Vatreciya Purba  , Rizky Akbar  , Muhammad Aqsha Rangkuti
Published: October 2024

Rehabilitation is crucial in aiding the recovery of drug addicts, emphasizing that the rehabilitation system influences individual behavior. The impact of a positive environmental system, including family support for the recovery of drug abuse victims, is very important. This research also explores the relationship between the rehabilitation system and resident behavior, aiming to enhance the effectiveness of rehabilitation programs and the well-being of residents. The 9-month recovery program at IPWL Bukit Doa aims to rehabilitate residents from drug addiction. The study emphasizes the importance of a positive environmental system in the recovery of individuals from drug abuse. Family support and a good environment are essential for successful recovery. This research also highlights the influence of the rehabilitation system on resident behavior, with the goal of improving the effectiveness of rehabilitation programs. The research shows that the 9-month recovery program is not always successful due to poor environments and lack of family support. The environment plays a significant role in individual behavior, with 74% being influenced by the environment. Although the 9-month recovery program at IPWL Bukit Doa aims to prevent relapse, the success of relapse prevention is not guaranteed due to environmental factors such as lack of family support and unsupportive environments often triggering relapse.