bluuebunny/crossref_metadata_2025 huggingface dataset:
Fixed point theorems in complete modular metric spaces and an application to anti-periodic boundary value problems
Authors: Aksoy Ümit , Karapınar Erdal , Erhan İnci
Published: March 2018

In this paper existence and uniqueness of fixed points for a general class of
contractive and nonexpansive mappings on modular metric spaces is discussed.
As an application of the theoretical results, the existence of a solution of
anti-periodic boundary value problems for nonlinear first order differential
equations of Carath?odory?s type is considered in the framework of modular
metric spaces.
The role of physical therapy in the treatment of children with chronic functional constipation
Authors: Savic Natasa , Zivkovic Vesna , Stankovic Ivona , Stojkovic Tatjana , Milenkovic Marina , Stojanovic Zorica , Balov Biljana
Published: March 2018

nema
Big N Auditors and Audit Quality: New Evidence from Quasi-Experiments
Authors: Jiang John (Xuefeng) , Wang Isabel Yanyan , Wang K. Philip
Published: March 2018

Whether Big N auditors provide higher audit quality than non-Big N auditors remains a debate. We add new evidence to this debate by utilizing the setting of Big N auditors' acquisitions of non-Big N auditors. We identify 331 treatment firms that switched to Big N auditors due to the exogenous shocks imposed by Big N acquisitions. Our difference-in-differences analyses show that treatment firms' audit quality improves after switching to Big N auditors. In comparison, mergers or acquisitions among non-Big Ns have little impact on audit quality. Our cross-sectional analyses suggest the audit quality improvement among treatment firms is more likely due to Big N auditors' general competence rather than their industry-specific expertise. Finally, we find that treatment firms experience no significant market reactions around the announcements of Big N acquisitions, indicating that the capital markets may not attach any premium to the improved audit quality associated with Big N auditors.

JEL Classifications: M41; M49.
The Revolving Door of Sell-Side Analysts
Authors: Lourie Ben
Published: March 2018

Equity analysts are often hired by firms they cover. I document the extent to which this revolving door phenomenon impairs analysts' independence. I do this by examining the presence of biased research reports issued during the year before analysts are employed by a firm they cover. I find that during their final year, revolving door analysts bias their EPS forecasts, their target prices, and their recommendations in a direction that suggests that they are attempting to gain favor from their prospective employers. Specifically, relative to other analysts, revolving door analysts issue more optimistic reports on the firms that hire them, and they issue more pessimistic reports on firms that do not hire them. These results suggest the presence of strategic bias, although more innocuous interpretations cannot be completely ruled out.

JEL Classifications: G14; G17; G24; G28; M41.

Data Availability: Data are available from public sources identified in the text.
Relationship Between Metabolic Syndrome, Alanine Aminotransferase Levels, and Liver Disease Severity in a Multiethnic North American Cohort With Chronic Hepatitis B
Authors: Khalili Mandana , Shuhart Margaret C. , Lombardero Manuel , Feld Jordan J. , Kleiner David E. , Chung Raymond T. , Terrault Norah A. , Lisker-Melman Mauricio , Sanyal Arun , Lok Anna S. ,   for the Hepatitis B Research Network (HBRN)
Published: March 2018

OBJECTIVE

Metabolic syndrome (MS) is prevalent and is associated with adverse outcomes of liver disease. We evaluated the prevalence of MS and its influence on alanine aminotransferase (ALT) levels and fibrosis, as estimated by the aspartate aminotransferase–to–platelet ratio index (APRI), in a large, multiethnic North American cohort with chronic hepatitis B (HBV) infection.

RESEARCH DESIGN AND METHODS

Adults with chronic HBV from 21 centers within the U.S. and Canada were evaluated at baseline and for up to 5 years (median 3.7 years) of follow-up. MS was defined as the presence of at least three of five criteria including waist circumference, blood pressure, glucose, triglyceride, and HDL levels.

RESULTS

Analysis included 777 participants, of whom 171 (22%) had MS. Participants with MS (vs. those without MS) were older (median age 54.4 vs. 40.2 years), more often male (61% vs. 51%), and born in the U.S./Canada or had immigrated >20 years ago (60% vs. 43%). MS was not associated with ALT or APRI at baseline. Upon adjusted multivariable analysis of serial ALT values, ALT was significantly higher (mean 12%; P = 0.02) among those with MS at baseline and even higher (mean 19%; P = 0.003) among those with persistent MS compared with those with persistent absence of MS. MS was not associated with serial APRI on follow-up.

CONCLUSIONS

MS was prevalent in this HBV cohort and was independently associated with higher ALT levels longitudinally. These findings highlight the importance of screening for MS and the potential for MS to influence ALT and its interpretation in the context of HBV treatment decisions.
Religión civil estadounidense: auge de un pueblo elegido y su crisis actual
Authors: Sanchez Rodriguez Eva María
Published: March 2018

¿Cómo es posible hablar de una religión civil estadounidense? ¿Y cómo se genero su identidad nacional? ¿Qué significa ser estadounidense hoy en día y cómo se relaciona con los demás? Este libro parte del problema identitario reactivado con la globalización y sus crisis, por lo que se ha vuelto a prestar atención al factor religioso. Como afirma su autor, dicho problema resulta más complejo y confuso por los velos posmodernos (v.g. relativismo, corrección política, pensamiento débil), y más aún en los Estados Unidos de América (EE.UU.), dificultándose así su urgente y necesaria revisión identitaria y solidaria a día de hoy.
Ticagrelor-related late-onset dyspnea as cause of emergency department visit: a 3-year outpatient study
Authors: Lombardi Niccolò , Lucenteforte Ersilia , Torrini Monica , Balzi Daniela , Barchielli Alessandro , Mugelli Alessandro , Vannacci Alfredo
Published: March 2018

Introduction

The aim of the current study was to define the rate of emergency department visits for late-onset dyspnea in acute coronary syndrome patients treated with ticagrelor.

Methods

We conducted a population-based study on about 850 000 residents of Florence metropolitan area, by using data from healthcare records.

Results

Between 2012 and 2014, 1073 subjects in Florence metropolitan area had at least one prescription of ticagrelor. Two-hundred and thirty-four patients were diagnosed with ‘respiratory system or other chest symptoms’ or ‘other diseases of lung’, and among them we identified 20 subjects with ticagrelor-related late-onset dyspnea. These, and the 979 nonevent subjects (receiving ticagrelor but not developing dyspnea), contributed to 413 person-years overall. The dyspnea rate was 4.84 per 100 person-years (95% confidence interval: 3.12–7.51).

Conclusion

Late-onset dyspnea rate is notably lower than early-onset one; nevertheless prescribing clinicians should be aware that about one in 20 outpatients with a stabilized ticagrelor treatment might develop a dyspnea leading to an emergency department visit, and they should consider ticagrelor replacement only in patients who cannot tolerate dyspnea.
Outcome of elective cholecystectomy for the treatment of gallbladder disease in dogs
Authors: Youn Gabina , Waschak Michelle J. , Kunkel Kevin A. R. , Gerard Patrick D.
Published: March 2018

OBJECTIVE To determine mortality rates for dogs undergoing cholecystectomy and variables associated with failure to survive to hospital discharge.

DESIGN Retrospective cohort study.

ANIMALS 70 dogs that underwent cholecystectomy for biliary tract disease at a companion animal referral hospital from 2009 through 2015.

PROCEDURES Medical records of dogs were reviewed and data collected; dogs with biliary diversion surgery were excluded. Included dogs were grouped by whether cholecystectomy had been elective (ie, dogs with no or mild clinical signs, with no indication of biliary obstruction, or that initially underwent surgery for a different procedure) or nonelective (ie, dogs with icterus and questionable patency of the biliary system). Mortality rates (proportions of dogs that failed to survive to hospital discharge) were compared between various groups.

RESULTS 45 (64%) dogs were included in the elective group and 25 (36%) in the nonelective group. Group mortality rates were 2% (1/45) and 20% (5/25), respectively, and differed significantly. Overall mortality rate was 9% (6/70). Serum albumin concentration was significantly lower and serum alanine aminotransferase activity and total bilirubin concentration were significantly higher in nonsurviving versus surviving dogs. Dogs with vomiting, signs of lethargy or anorexia, icterus, or azotemia were less likely to survive than dogs without these signs.

CONCLUSIONS AND CLINICAL RELEVANCE Dogs that underwent elective cholecystectomy had a considerably lower mortality rate than previously reported. Elective cholecystectomy may be an appropriate recommendation for dogs with early signs of biliary disease to avoid the greater mortality rate associated with more advanced disease and nonelective cholecystectomy.
Multi-Criteria Analysis and Prediction of Network Incidents Using Monitoring System
Authors: Macura Lukas , Voznak Miroslav
Published: March 2018

Today, network technologies can handle throughputs up to 100Gbps, transporting 200 million packets per second on a single link. Such high bandwidths impact network flow analysis and as a result require significantly more powerful hardware. Methods used today concentrate mainly on analyzes of data flows and patterns. It is nearly impossible to actively look for anomalies in network packets and flows for a small amount of change of monitoring patterns could result in big increases in potentially false positive incidents. This paper focuses on multi-criteria analyzes of systems generated data in order to predict incidents. We prove that systems generated monitoring data are an appropriate source to analyze and enable for much more focused and less computationally intensive monitoring operations. By using appropriate mathematical methods to analyze stored data it is possible to obtain useful information. During our work, some interesting anomalies in networks were found by utilizing simple data correlations using monitoring system Zabbix. We concluded that it is possible to declare that deeper analysis is possible due to Zabbix monitoring system and its features like Open-Source core, documented API and SQL backend for data. The result of this work is a new approach to the analysis containing algorithms which allow to identify significant items in monitoring system. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
An Effective Approach of Approximation of Fractional Order System using Real Interpolation Method
Authors: Nguyen Dung Quang
Published: March 2018

Fractional-order controllers are recognized to guarantee better closed-loop performance and robustness than conventional integer-order controllers. However, fractional-order transfer functions make time, frequency domain analysis and simulation significantly difficult. In practice, the popular way to overcome these difficulties is linearization of the fractional-order system. Here, a systematic approach is proposed for linearizing the transfer function of fractional-order systems. This approach is based on the real interpolation method (RIM) to approximate fractional-order transfer function (FOTF) by rational-order transfer function. The proposed method is implemented and compared to CFE high-frequency method; Carlson’s method; Matsuda’s method; Chare ’s method; Oustaloup’s method; least-squares, frequency interpolation method (FIM). The results of comparison show that, the method is simple, computationally efficient, flexible, and more accurate in time domain than the above considered methods.  This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Differential Evolution Dynamics Analysis Using Aggregated Networks
Authors: Skanderova Lenka , Zelinka Ivan
Published: March 2018

In this paper, the dynamics of the selected variants of the differential evolution is modelled by aggregated network capturing the relationships between individuals established during the population evolution. The motivation of this research is to better understand the relationships between individuals of the selected variants of the differential evolution. Thanks to the analysis of the aggregated networks, the advantages as well as bottlenecks of the selected algorithms can be specified more precisely and the results of the analysis can be used to develop novel algorithms. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Adaptive MIMO Controller Design for Chaos Synchronization in Coupled Josephson Junctions via Fuzzy Neural Networks
Authors: Nguyen Thien Bao Tat
Published: March 2018

In this paper, we have discussed the synchronization between coupled Josephson Junctions which experience different chaotic oscillations. Due to potential high-frequency applications, the shunted nonlinear resistive-capacitive-inductance junction (RCLSJ) model of Josephson junction was considered in this paper. In order to obtain the synchronization, an adaptive MIMO controller is developed to drive the states of the slave chaotic junction to follow the states of the master chaotic junction. The developed controller has two parts: the fuzzy neural controller and the sliding mode controller. The fuzzy neural controller employs a fuzzy neural network to simulate the behavior of the ideal feedback linearization controller, while the sliding mode controller is used to ensure the robustness of the controlled system and reduce the undesired effects of the estimate errors. In addition, the Lyapunov candidate function is also given for further stability analysis. The numerical simulations are carried out to verify the validity of the proposed control approach. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Factors Influencing the Intentions of Using Tax Consulting Services of Firms in Ho Chi Minh City: A Structural Equation Model
Authors: Nguyen-Trang Thao , Vu-Hoang Long , Nguyen-Thi Trieu , Che-Ngoc Ha
Published: March 2018

Tax consulting service is one of various professional consulting services and is interested to study by many researchers. Nevertheless, this issue has not been interested to research in Vietnam. This paper performs confirmatory factors analysis (CFA) and structural equation modeling (SEM) to identify the factors influencing the intentions of using tax consulting services of firms in Ho Chi Minh city, Vietnam. Specifically, this paper finds that the intentions depend on the “attitude toward the behavior” and “replacement”. In addition, through Chi-square test, it can be proven that the intentions also depend on type of firms and whether they have ever used tax consulting service or not. Based on the obtained results, the discussion and recommendation are also proposed. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Static Analysis of a Tire Sidewall Developed From Tailored Organomodified Kaolin/Natural Rubber Vulcanizates
Authors: Mgbemena Chinedum Ogonna , Boye ThankGod Enatimi , Emovon Ikuobase
Published: March 2018

This paper is on the prediction of stress limits and strain distributions of an automobile tire sidewall developed from Natural Rubber (NR)/Tea Seed Oil (TSO) modified kaolin composites. The stress-strain data report of NR/TSO modified kaolin at filler loading of 10phr was used to establish parameters characterizing the elastic behavior of the rubber vulcanizates. The tire model investigated was developed from MATLAB PDE Toolbox. The study was developed on maximum inflation pressure of 0.220632 MPa. The 2D Finite Element (FE) model computations for static loading of the tire sidewall gave a reasonable prediction of the stress limits and strain distributions, as the shear stresses obtained were within the range of −10 MPa to 10 MPa. The strain energy distributions were found to be within the range of −1500 J·m−3 to 1500 J·m−3. The stress limits for the first principal stress with respect to their magnitudes and orientations was obtained as 10 MPa for tensile stress and −20 MPa for compressive stress respectively while the stress limits for the second principal stress was obtained as 20 MPa for tensile stress and −10 MPa for compressive stress. The plane stress analysis with MATLAB PDE Toolbox gave stress limits distribution in terms of von-Mises stresses in the range 5 MPa - 25 MPa. The results indicate that NR/TSO modified kaolin composites can be employed in automobile tire sidewall applications.  This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Akreditasi Jurnal
Authors: Alamsyah Agus
Published: March 2018

AKREDITASI JURNAL

Jurnal Kesehatan Komunitas sudah terindeks di Portal Garuda, SINTA, Direktory of  Open Access Journals (DOAJ) dan beberapa pengindeks lainnya. Tahun 2019 Jurnal Kesehatan Komunitas merencanakan mengajukan akreditasi berkala ilmiah elektronik ke Kementerian Riset, Teknologi, dan Pendidikan Tinggi. Menurut Permenristekdikti  No. 20  Tahun 2017 dinyatakan bahwa Jurnal Ilmiah Nasional terakreditasi B dari Kemristekdikti yang diterbitkan dalam salah satu bahasa PBB, terindeks di DOAJ dengan indikator green thick (centang dalam lingkaran hijau)  disetarakan/diakui sebagai jurnal internasional; dan Jurnal Ilmiah Nasional terakreditasi A dari Kemristekdikti yang diterbitkan dalam salah satu bahasa PBB, terindeks di DOAJ dengan indikator green thick (centang dalam lingkaran hijau)  disetarakan/diakui sebagai jurnal internasional bereputasi. Untuk mencapai Jurnal Kesehatan Komunitas terakreditasi minimal B, salah satu usaha yang dilakukan adalah dengan manajemen jurnal yang baik dengan mengikuti kaidah atau ketentuan yang telah ditetapkan oleh Kemenristekdikti diantaranya melewati proses peer review.

Adapun persyaratan akreditasi untuk berkala ilmiah elektronik berdasarkan surat edaran kemenristekdikti No 101/E5.2/SE/2018 tentang akreditasi berkala ilmiah elektronik adalah memiliki ISSN dalam versi elektronik (e-ISSN) dan atau cetak (p-ISSN) bila terbitan terbit dalam dua versi, sesuai data di laman http://issn.pdii.lipi.go.id; mencantumkan persyaratan etika publikasi (publication ethics statement) dalam laman website jurnal; terbitan berkala ilmiah harus bersifat ilmiah, artinya memuat artikel yang secara nyata mengandung data dan informasi yang memajukan pengetahuan, ilmu, dan teknologi serta seni; terbitan berkala ilmiah telah terbit paling sedikit 2 tahun berurutan, terhitung mundur mulai tanggal atau bulan pengajuan akreditasi; frekuensi penerbitan berkala ilmiah paling sedikit 2 kali dalam satu tahun secara teratur; jumlah artikel setiap terbit sekurang-kurangnya 5 artikel, kecuali jika berbentuk monograf; dan tercantum dalam salah satu lembaga pengindeks nasional (Indonesian Scientific Journal Database (ISJD), Portal Garuda, Pustaka Iptek dan/atau yang setara).

Jurnal Kesehatan Komunitas telah memenuhi semua persyaratan tersebut di atas dan penilaian di Science and Technology Index (Sinta), Jurnal Kesehatan Komunitas berada di klaster S4. Berdasarkan hal tersebut, tim redaksi Jurnal Kesehatan Komunitas yakin bahwa akreditasi berkala ilmiah elektronik tersebut bisa dicapai tentunya dengan team work yang solid, baik antara tim redaksi, reviewer, penulis (author), maupun pihak  STIKes Hang Tuah Pekanbaru yang mendukung penerbitan Jurnal Kesehatan Komunitas.
O REGISTRO CIVIL DAS PESSOAS NATURAIS CONTRIBUINDO PARA A CONCRETIZAÇÃO DA CIDADANIA E DA DIGNIDADE DA PESSOA HUMANA
Authors: Mattos Voltolini Gustavo Henrique , Dos Reis Silveira Ricardo
Published: March 2018

A Constituição Federal de 1988 estabelece como fundamentos da República Federativa do Brasil, dentre outros, a cidadania e a dignidade da pessoa humana. Tais direitos, pelo menos nas serventias extrajudiciais de Registro Civil das Pessoas Naturais, são concretizados ao se realizar gratuitamente os registros de nascimento e de óbito, bem como expedir as primeiras certidões. Para os reconhecidamente pobres também são expedidas gratuitamente as demais certidões e feitos outros registros. Pelo menos nesse quesito a Constituição brasileira, na classificação de Karl Loewenstein, pode ser considerada normativa.
DECLARAÇÃO UNIVERSAL DOS DIREITOS HUMANOS: A VISÃO DE JACQUES MARITAIN
Authors: Pozzoli Lafayette , Lacerda Luana Pereira
Published: March 2018

Os ensinamentos de Jacques Maritainpara com os direitos humanosafirmam a dignidade humana como um valor caríssimo a ser preservado, bem como a liberdade da pessoa humana. Nessa vereda, o ser humano é reconhecido como tal pela sua natureza, portanto, sujeito de direitos e deveres. Com isso, a pessoa humana, dotada de razão, deve ser capaz de viver emsociedade de forma harmônica, buscando o bem comum e fazendo uso do direito, além dopositivismo, ou seja, fundamentando-se na Lei Natural. Primou-se pela utilização do método dedutivo e técnicas de coleta de dados bibliográficos, documentaise via internet.
LIVING LABS AS A PEDAGOGICAL TEACHING TOOL FOR GREEN BUILDING DESIGN AND CONSTRUCTION IN HOT ARID REGIONS
Authors: Dabaieh Marwa , El Mahdy Deena , Maguid Dalya
Published: March 2018

Sustainability and environmental illiteracy is still common in architectural curricula for undergraduate education. This may lead to further generations of architects who are unequipped for global sustainability goals. This paper discusses a living lab teaching experience which investigates the roles of learning through doing and hands-on building experimentation to root an understanding of sustainability in architectural education. The design studio at the centre of this paper was focused on passive, low-cost and energy-efficient approaches suitable for a hot arid climate. The students were asked to design a refugee shelter prototype that was cost- and time-efficient, that would also present the least impact on the environment after demolition. The course’s teaching process also included invited guest speakers, field trips and a hands-on workshop for low-tech building techniques as a prelude to designing and building a full-scale physical model. Thermal comfort and energy consumption for the design proposal were evaluated by simulation, and the physical model was evaluated by field monitoring. This paper outlines the design studio pedagogical experimental living lab process and the resulting students’ projects. It also shows the various skills the students acquired and suggests how this type of pedagogy can be viewed as a pilot model for green architecture education.
Culture and Architecture in Distress - Sarajevo Experiment
Authors: Zejnilovic Emina , Husukic Erna
Published: March 2018

This paper attempts to discuss the reciprocal connection between culture and architecture as a social product. In doing so, the paper intends to critically engage with the theme of ‘culture’, its impact on residential developments, and its character in the process of recuperation of post-war society in Sarajevo. The development of residential architecture is followed through the four historical periods that had the greatest impact on its formation. Setting the scene to better understand the current built design challenges, post-war, post-socialist culture and architecture are analysed through the lens of T.S. Elliot's (1948) theory on culture. Specifically, the paper refers to the criteria Elliot defined as essential for a culture to survive; Organic Structure, Regional Context and Balance & Unity in Religion. Finally, the paper identifies the main obstacles in the process of cultural transformation of Sarajevo, indicating an urgent need for addressing the issues of cultural and architectural vitality.
USING THE DIGITAL CONTEXT TO OVERCOME DESIGN FIXATION: A STRATEGY TO EXPAND STUDENTS’ DESIGN THINKING
Authors: Choi Han Hee , Kim Mi Jeong
Published: March 2018

Design fixation has been described as a lack of flexibility in relation to a limited set of design ideas. This study empirically sought to use different strategies to overcome various forms of design fixation. As strategic approaches to negating design fixation, a digital world that has no physical limitations was selected as a thinking expansion motif and an abstract task was given as a design problem. It was anticipated that combining limitlessness of the digital world with an abstract design task would break design fixation, leading to a creative design process. The results supported the usefulness of the adopted strategies. The combination of the digital context and the design task overcame participants’ design fixation and encouraged the creative design process by generating thinking expansion. Further, combining ‘Team Based Learning’ and an ‘abstract design task in a digital context’ led to natural brainstorming and problem solving that exhibited co-evolution. In conclusion, the digital context is one of promising strategies that could be used as a thinking motif to expand students’ design thinking and promote ‘creativity’ in education.
TEACHING INNOVATION AND THE USE OF SOCIAL NETWORKS IN ARCHITECTURE: LEARNING BUILDING SERVICES DESIGN FOR SMART AND ENERGY EFFICIENT BUILDINGS
Authors: Domínguez-Amarillo Samuel , Fernandez-Aguera Jesica , Fernandez-Aguera Patricia
Published: March 2018

Today’s buildings are evolving from structures comprising unchanging, static elements scantly able to interact with their surroundings, towards complex systemic compounds with an impact on the environs that entails more than mere anthropic alteration. In pursuit of energy efficiency and true sustainability, buildings must acquire the ability to interact as well as to generate synergies. The most prominent features of this approach are energy management and information flows which, intelligently designed, not only enhance buildings’ capabilities, but also introduce a significant change in their relationship with the surrounds (‘smart cities’) and its inhabitants. This new paradigm calls for revisiting undergraduate architectural instruction, adopting a more complex overview of energy use and management in the design process, regarding buildings as dynamic rather than static entities. The methodology focuses on creating learning environments that favour students’ participation in problem solving and assessment, encouraging teamwork based on case studies and stressing the connection between this new architecture, ICTs included, and social networks as participatory design tools. These ideas were implemented in a pilot learning experience conducted at the University of Seville for undergraduate students. The use of ICTs and the collaboration of non-academic experts were observed to further student promotion and projection beyond the academic environment and introduce them to the professional community.
BOOK REVIEW: DESIGN FOR GOOD: A NEW ERA OF ARCHITECTURE FOR EVERYONE
Authors: Van Riel Kristijn
Published: March 2018

‘Design for Good: A New Era of Architecture for Everyone’ written by John Cary deals with the general topic of social justice in the built environment with a focus on architectural interventions in marginalised communities. The book argues for public interest design and its main message is important and clear: architects can and should serve the public interest, and not only the interest of a privileged few. Everyone deserves good design. In the last fifteen years the proliferation of the social responsibilities of architects and designers is witnessed in the establishment of several important organisations and design firms emphasising social impact as central to their work. Despite following a positive trend, in the global scheme of things, this practice remains rare and is worthy of bringing to the attention of the wider design community and the general population. The book achieves several important objectives: It highlights new ways in which good design can have an impact on the lives of people, especially within deprived communities. It also makes an urgent appeal to designers and community organisations to embrace the principles of public interest design. Simultaneously, it emphasises the long way forward before the wealth of designers worldwide can be successfully tapped for the public good, and articulates a range of challenges for the future.
A case of respiratory toxigenic diphtheria: contact tracing results and considerations following a 30-year disease-free interval, Catalonia, Spain, 2015
Authors: Jané Mireia , Vidal Maria José , Camps Neus , Campins Magda , Martínez Ana , Balcells Joan , Martin-Gomez Maria Teresa , Bassets Gloria , Herrera-León Silvia , Foguet Anton , Maresma Mar , Follia Nuria , Uriona Sonia , Pumarola Tomàs
Published: March 2018

In May 2015, following a 30-year diphtheria-free interval in Catalonia, an unvaccinated 6-year-old child was diagnosed with diphtheria caused by toxigenic Corynebacterium diphtheriae. After a difficult search for equine-derived diphtheria antitoxin (DAT), the child received the DAT 4 days later but died at the end of June. Two hundred and seventeen contacts were identified in relation to the index case, and their vaccination statuses were analysed, updated and completed. Of these, 140 contacts underwent physical examination and throat swabs were taken from them for analysis. Results were positive for toxigenic C. diphtheriae in 10 contacts; nine were asymptomatic vaccinated children who had been in contact with the index case and one was a parent of one of the nine children. Active surveillance of the 217 contacts was initiated by healthcare workers from hospitals and primary healthcare centres, together with public health epidemiological support. Lack of availability of DAT was an issue in our case. Such lack could be circumvented by the implementation of an international fast-track procedure to obtain it in a timely manner. Maintaining primary vaccination coverage for children and increasing booster-dose immunisation against diphtheria in the adult population is of key importance.
Vortex-Induced Vibrations of a Low-tension Cable-Sheave System Modeled using Nonlinear Finite Elements
Authors: Westin Cassidy , Irani Rishad A.
Published: March 2018

This work presents a finite element model of a cable-sheave system constructed to model cable vibrations due to vortex shedding in low-tension cases. The study assesses the potential for vortex shedding to lead to detachment of the cable from the sheave. The absolute nodal coordinate formulation is utilized to define the cable structural dynamics. Vortex shedding forces are incorporated by coupling the cable's equations of motion to a Van der Pol equation, also known as a wake-oscillator and the cable-sheave interaction is described using a contact penalty method. The study examines the contribution of vortex shedding occurring at the cable's natural frequency to the cable motion. For the cases studied the model demonstrates that vortex shedding alone results in very small vibration amplitudes and thus is unlikely to result in cable detachment.
ЙМОВІРНІСНЕ МОДЕЛЮВАННЯ ВПЛИВУ ШВИДКОСТІ ДЕФОРМАЦІЇ НА НАПРУЖЕНО-ДЕФОРМОВАНИЙ СТАН МАТЕРІАЛУ
Authors: Astanin V. V. , Olefir О. І. , Shchegel G. О. , Olefir А. О.
Published: March 2018

Запропонована ймовірнісна модель врахування впливу швидкості деформації на напружено-деформований стан матеріалу. Показано її застосовність для розрахунку переходу від пружного до пластичного деформування, відповідних відносних деформацій і напружень границі текучості залежно від швидкості деформації, а також переваги її застосування порівняно із традиційною феноменологічною моделлю з точки зору зменшення величини похибки розрахунку відносно експериментальних даних.
IDENTIFIKASI SALURAN PEMASARAN KOPI ARABIKA GAYO PADA CV. GAYO MANDIRI COFFEE KABUPATEN BENER MERIAH
Authors: Praza Riyandhi
Published: March 2018

The high selling price of coffee paid by consumers (importers) has not been felt by farmers. The development of Gayo Arabica Coffee marketing then emerged Cooperative and CV in Bener Meriah Regency in accommodating the production of farmers one of them. CV.Gayo Mandiri Coffee (GMC) located in District Bandar, Bener Meriah Regency. CV Gayo Mandiri Coffee is engaged in Gayo Arabica coffee marketing activities. This study aims to identify the marketing channel and the Gayo Arabica coffee production process. The research was conducted using qualitative descriptive method to analyze the primary and secondary data obtained. Primary data obtained through interviews and observations, while secondary data obtained through the literature associated with this research. Gayo Arabica coffee marketing in CV.Gayo Mandiri Coffee in marketing its products there are two channels, from collectors to producers to consumers, from producers directly to consumers and from producers to retailers as well as through intermediaries then to the hands of consumers. The most dominant channels contained in CV.Gayo Mandiri is channel I because this channel is the most effective and efficient in the marketing of green bean coffee Arabica Gayo.
ANALISIS KEUNGGULAN KOMPARATIF DAN KOMPETITIF BERAS SOLOK ORGANIK
Authors: Mardianto Mardianto , Firnando Edi
Published: March 2018

Penelitian tentang Analisis Keunggulan Komparatif dan Kompetitif Beras SolokOrganik dilakukan di Kecamatan Gunung Talang Kabupaten Solok yang bertujuan untuk mengetahui keunggulan komparatif dan keunggulan kompetitif beras solok organik danuntuk melihat dampak kebijakan pemerintah terhadap beras solok organic. Penelitian inidilaksanakan dengan metoda case study. Pengambilan sampel dilakukan dengan sensus.Metoda Analisa yang digunakan adalah : policy análisis matrik (PAM). Hasil penelitianmenunjukan bahwa usahatani beras solok organik memiliki keunggulan komparatif dankompetitif dengan nilai PCR < 1 (0,103) dan DRCR < 1 (0,125),  sehingga secara finansialusahatani beras solok sudah efisien dan memiliki potensi dalam perdagangan di pasarbebas. Nilai EPC yang diperoleh besar dari 1 (1,219) berarti bahwa usahatani beras solokorganik efektif untuk dilaksanakan dengan adanya kebijakan output dan input.  Sedangkan kebijakan perlindungan yang diterapkan pemerintah masih memberikaninsentif kepada petani sebagi produsen beras solok organik karena nilai NT>0 dan PC>1.Tanpa adanya distorsi pasar yang dilakukan oleh pemerintah maka penerimaan petaniakan naik 15,7 % yang ditunjukan oleh Nilai SRP (0,157).
FAKTOR-FAKTOR YANG MEMPENGARUHI PENGAMBILAN KEPUTUSAN PETANI TERHADAP PENGGUNAAN BENIH PADI DI KECAMATAN NISAM KABUPATEN ACEH UTARA
Authors: Rahmi Hayatul , Fadli Fadli
Published: March 2018

Pengambilan keputusan petani terhadap penggunaan benih padi merupakan salah satu faktor penentu pencapaian hasil optimal dalam suatu usahatani, karena jika salah memilih jenis benih padi maka hasil yang dicapai tidak optimal. Penelitian ini bertujuan untuk menganalisis faktor apa saja yang mempengaruhi keputusan petani terhadap penggunaan benih padi di Kecamatan Nisam Kabupaten Aceh Utara. Metode pengambilan sampel dalam penelitian ini menggunakan Multi Stage Random Sampling dan untuk menentukan besaran sampel digunakan rumus Slovin. Analisis data penelitian menggunakan metode Analisis Regresi Logistik dengan bantuan software SPSS 16. Dari hasil penelitian menunjukkan bahwa ada tiga variabel yang mempengaruhi keputusan petani terhadap penggunaan benih padi yaitu luas lahan, produksi, dan harga benih padi.Sedangkan faktor pendapatan tidak mempengaruhi petani dalam menggunakan benih padi.
PERSEPSI PETANI LADA ACEH TERHADAP PELAKSANAAN PENYULUHAN PERTANIAN KERJASAMA PERGURUAN TINGGI
Authors: Budi Setia
Published: March 2018

Secara umum penelitian ini bertujuan untuk mendapatkan data dasar (data base) tentang model kegiatan pemberdayaan melalui penyuluhan pertanian kerja sama perguruan tinggi dengan masyarakat tani Gampong Pulo Iboih sebagai desa binaan Universitas Malikussaleh. Secara khusus penelitian ini bertujuan untuk mengetahui persepsi petani lada terhadap pelaksanaan penyuluhan kerjasama perguruan tinggi di Gampong Pulo Iboih. Metode penelitian yang digunakan dalam penelitian ini metode penelitian kualitatif studi kasus pada kelompok petani lada dan pengolahan datanya statistik non parametric dengan pengukuran data mengunakan skala likert. Hasil penelitian menunjukkan persepsi petani lada terhadap penyuluh pertanian yang sangat baik dirasakan oleh petani lada Gampong Pulo Iboih, secara berurutan meliputi; (1) peran penyuluh dalam melakukan pelatihan budidaya, (2), peran penyuluh sebagai pihak penghubung antara petani lada dengan pihak luar (3) peran penyuluh pertanian perecanaan dan pengawasan program budidaya lada serta (4) peran penyuluh dalam penguatan kelompok . Pesepsi petani Petani lada terhadap peran penyuluh dari perguruan tinggi dalam tahapan proses penyuluhan pertanian pada pelaksanaan penyuluhanan pertanian secara berurutan meliputi; (1) ketepatan pengunaan media, (2) kesesuaian metoda penyuluhan, (3) kesesuaian materi penyuluhan dan (4) intensitas pelaksanaan penyuluhan.
ANALISIS BAURAN PEMASARAN TEH HERBAL ASAM GELUGUR (GARCIE TEA) PADA KOMUNITAS LOKAL BIOVERSITY DI KABUPATEN SIJUNJUNG
Authors: Yanti Rani Rahmi , Novarista Noni
Published: March 2018

Penelitian ini bertujuan untuk mengetahui : (1) bauran pemasaran teh herbal asam gelugur pada Komunitas Lokal Bioversity (2) kendala apa saja yang dihadapi oleh Komunitas Lokal Bioversity dalam memasarkan teh herbal asam gelugur. Penelitian ini dilakukan di Nagari Latang Kecamatan Lubuk Tarok Kabupaten Sijunjung pada Komunitas Lokal Bioversity yang telah dilakukan pada bulan Mei–Desember 2016. Metode penelitian yang digunakan adalah metode studi kasus. Data yang digunakan terdiri atas data primer dan data sekunder. Data primer diperoleh secara langsung dari responden berupa hasil pengamatan langsung perolehan dokumen dan wawancara langsung. Data sekunder merupakan data tidak langsung yang diperoleh dari dokumen-dokumen. Metode analisis yang digunakan dalam penelitian ini adalah deskriptif kualitatif. Hasil yang diperoleh dari penelitian ini: 1) bauran produk yang ada di Komunitas Lokal Bioversity meliputi kualitas, desain, merek dan ukuran 2) bauran harga meliputi penetapan harga, potongan harga dan sistem pembayaran 3) bauran distribusi meliputi saluran pemasaran dan lokasi 4) bauran promosi meliputi pameran dagang, dan iklan. Kendala yang dihadapi dilihat pada segi internal dan eksternal, pada segi internal dilihat dari segi produk, harga, distribusi, dan promosi. Sedangkan untuk segi eksternal dilihat dari keberadaan pesaing.
KEBIJAKAN PENGEMBANGAN PARIWISATA DI KABUPATEN TANAH DATAR
Authors: Hendrita Vivi
Published: March 2018

Penelitian Kebijakan Pengembangan Pariwisata di Kabupaten Tanah Datar ini bertujuan untuk mengetahui kondisi dan perkembangan pariwisata di Kabupaten Tanah Datar serta menganalisis kebijakan dan upaya yang telah dilakukan pemerintah Kabupaten Tanah Datar dalam pengembangan pariwisata. Penelitian ini menggunakan metode deskriptif kualitatif yang dianalisa secara interpretative menggunakan teori-teori ataupun literatur-literatur yang sesuai kemudian secara induktif ditarik kesimpulan untuk menjawab permasalahan yang ada. Data dalam penelitian ini diperoleh dari wawancara, observasi lapangan dan studi literatur. Dari hasil penelitian didapat bahwa kondisi pengembangan pariwisata di Kabupaten Tanah Datar belum dilakukan secara optimal. Upaya yang dilakukan pemerintah Kabupaten Tanah Datar dalam mengembangan pariwisata terlihat dari berbagai kebijakan yang dibuat yang tercantum dalam renstra, dan RPJMD, serta didukung beberapa peraturan daerah dan peraturan Bupati Tanah Datar, namun dalam kebijakan ini masih terfokus pada pelaksanaan event dan promosi budaya dan belum menyentuh pengembangan terhadap objek wisata secara khusus sehingga dalam pelaksanaannya masih belum memperlihatkan perkembangan yang signifikan terhadap pengembangan sektor pariwisata di Kabupaten Tanah Datar.
Сравнительный анализ эффективности дексаметазона, гидроксиэтилкрахмала и гипертонического раствора хлорида натрия при остром респираторном дистресс-синдроме в эксперименте
Authors: Куликов Олег Александрович , Пятаев Николай Анатольевич , Инчина В. И. , Гуревич Константин Георгиевич , Заборовский Андрей Владимирович , Минаева Ольга Владимировна , Кокорев Александр Викторович
Published: March 2018

Исследовано влияние гипертонического раствора хлорида натрия и препарата ГиперХАЕС на показатели летальности, оксигенирующую функцию легких и кислотно-основное состояние у крыс при синдроме острого повреждения лёгких/остром респираторном дистресс-синдроме (СОПЛ/ОРДС). СОПЛ/ОРДС моделировали путем интратрахеального введения 0,1 мл/кг ацетона. Животные были разделены на 4 группы по 16 особей в каждой. Животные 1-й группы (контроль) препаратов не получали. Животным опытных групп проводили специфическую терапию, которая заключалась в однократном внутривенном введении исследуемых препаратов через 1 ч после интра-трахеального введения ацетона. Крысам 1-й опытной группы вводили дексаметазон в дозе 6 мг/кг, 2-й – 7,5 % раствор хлорида натрия в объёме 4 мл/кг, 3-й – 6 % раствор гидроксиэтилкрахмала в сочетании с 7,2 % раствором хлорида натрия (ГиперХАЕС) в дозе 4 мл/кг. Для оценки эффективности изучаемых методов терапии определяли частоту дыхания, показатели кислородного статуса и кислотно-основного состояния, а также фиксировали летальность на протяжении 6 сут от момента моделирования СОПЛ/ОРДС. Установлено, что все применяемые схемы улучшают результаты лечения СОПЛ/ОРДС, снижают общую смертность и смертность на ранних этапах лечения. В первые часы после аспирации ацетона они предотвращают развитие токсического отека легких и уменьшают выраженность гиповентиляции, на более поздних этапах – уменьшают выраженность диффузионных нарушений. Достоверных различий по влиянию на летальность и показатели оксигенации между применяемыми схемами терапии не выявлено.
Участие мелатонина в происхождении патологических процессов в костной ткани и их ограничении
Authors: Арушанян Эдуард Бениаминович
Published: March 2018

Мелатонин, продуцируемый эпифизом и клетками периферических тканей, посредством специфических рецепторов контролирует обмен в костной ткани и участвует в происхождении костной патологии. Современные экспериментальные доказательства его остеогенной активности позволяют рассматривать мелатонин в качестве потенциального лекарственного средства при различных видах заболеваний костей.
βIII-Тубулин — потенциальная мишень для подавления инвазивной активности злокачественных эпителиальных опухолей
Authors: Портянко Анна Сергеевна , Акалович Светлана Тадеушевна , Дорошенко Татьяна Михайловна
Published: March 2018

Инвазивный рост является первым шагом метастатического каскада злокачественных опухолей. Двигательная активность клеток, необходимый компонент инвазии, тесно связана с динамикой структур цитоскелета. Важную роль в обеспечении клеточной подвижности играют микротрубочки, которые состоят из тубулина — гетеродимера, содержащего α и β субъединицы, представленые различными изотипами. Появление в опухоли βIII-тубулина играет важную роль в прогнозе течения и химиорезистентности ряда опухолей человека. Данное исследование посвящено определению возможности использования βIII-тубулина в качестве молекулы-мишени для подавления инвазивного роста. Установлено, что блокирование экспрессии βIII-тубулина в клетках колоректального рака не влияет на их жизнеспособность, однако снижает адгезию к внеклеточному матриксу клеток линии HT-29 на 40 % (p = 0,0044), HCT 116 — на 15 % (p = 0,0436) и инвазивную активность в 4 раза (p = 0,0000 и p = 0,0001 соответственно). Данные факты позволяют рассматривать βIII-тубулин в качестве молекулы-мишени при разработке противоопухолевых лекарственных препаратов.
Мелатонин при аутоиммунной и аллергической патологии
Authors: Арушанян Э. Б.
Published: March 2018

Некоторым аутоиммунным и аллергическим заболеваниям (системная красная волчанка, рассеянный склероз, ревматоидный артрит и др.) сопутствуют нарушения выработки гормона мелатонина (МТ) эпифизом и периферическими тканями. Введение препаратов МТ при такой патологии животным и людям демонстрирует наличие у него протекторных свойств. Эти сведения позволяют рекомендовать более широкие испытания лечебных возможностей МТ при аутоиммунных болезнях для последующего внедрения в клиническую практику.
Facile Aromatisation of Hantzsch 1,4-Dihydropyridines by Autoxidation in the Presence of P-toluenesulfonic Acid in Acetic Acid
Authors: Zhang Ding , Sha Min
Published: March 2018

A simple protocol to achieve the aromatisation of Hantzsch dihydropyridines in high yield was established using p-toluenesulfonic acid in acetic acid and yields of 90% were obtained at room temperature. With regards to the Hantzsch 1,4-dihydropyridines derived from alkyl aldehydes bearing one or more á-hydrogens, dealkylation products were obtained through a proposed autoxidation mechanism.
An Efficient, Large-Scale Synthesis of Cytenamide
Authors: Bedford Colin T.
Published: March 2018

Dibenzosuberenone (5 H-dibenzo[a,d]cyclohepten-5-one) was reduced to the corresponding alcohol by sodium borohydride/MeOH and converted to the corresponding 5-chloro compound by thionyl chloride/benzene, treatment of which with CuCN/toluene gave the corresponding nitrile. Hydrolysis by ethanolic KOH yielded the corresponding amide, cytenamide (5 H-dibenzo[a,d]cycloheptene-5-carboxamide).
Egg Size and Shape Variation in Rufous Bush Chats Cercotrichas Galactotes Breeding in Date Palm Plantations: Hatching Success Increases with Egg Elongation
Authors: Adamou Ala-Eddine , Tabib Rabie , Kouidri Mohamed , Ouakid Mohamed Laïd , Glądalski Michał , Bańbura Jerzy
Published: March 2018

In oviparous taxa such as birds, clutch characteristics (e.g. egg size, egg mass and the number of eggs) can be considered as energetic investment in reproduction. In this paper, we study variation in the principal component indices of egg size and shape in Rufous Bush Chats (Cercotrichas galactotes) breeding in date palm plantations in the Al Amri Oasis, north Algeria, in 2008–2009 and 2011–2013. For descriptive and comparative purposes, we also present characteristics of egg length, breadth, volume, shape and mass. The size and shape indices as well as dimensions and masses of the eggs laid by particular females tended to be similar to one another, with most variation occurring between clutches (significant repeatabilities for all egg traits). Variation in the size of eggs was influenced by the year-laying date interaction, while variation in the shape (elongation) of eggs was marginally significantly affected by the year-laying date interaction. Year had a significant factor effect on the size of eggs. We also found that hatching success was affected by interactions between year and egg size and shape principal components, thus confirming the existence of fitness-related consequences of variation in the traits of Rufous Bush Chat eggs. Notably, we found that in some years hatching success increased with the elongation of eggs.