bluuebunny/crossref_metadata_2025 huggingface dataset:
The Dynamics of Food Web Model with Defensive Switching Property
Authors: Naji R. K. K. , Kasim I. H. H.
Published: October 2019

In this paper, a food web model consisting of two-predator one-prey with the defensive switching of predation avoidance is proposed and analyzed. It is assumed that the prey growth logistically in the absence of predators and defends itself from relatively abundant predator species by switching to another habitat with relatively rare predator species. Sufficient conditions for the stability of the non-trivial equilibrium point are obtained. The Lyapunov function is constructed to establish the global asymptotic stability of the non-trivial equilibrium point when the intensity of defensive switching equal one. Numerical simulations for different sets of parameter values and for different sets of initial conditions are carried out. It has been shown that the system has a globally asymptotically stable non-trivial point when the two predators have the same mortality rates.
Analysis of an Antiplane Contact Problem with Adhesion for Electro-Viscoelastic Materials
Authors: Sofonea M. , Chouchane L. , Selmani L.
Published: October 2019

We consider a mathematical model which describes the antiplane shear deformation of a cylinder in frictionless contact with a rigid foundation. The adhesion of the contact surfaces, caused by the glue, is taken into account. The material is assumed to be electro-viscoelastic and the foundation is assumed to be electrically conductive. We derive a variational formulation of the model which is given by a system coupling an evolutionary variational equality for the displacement field, a time-dependent variational equation for the electric potential field and a differential equation for the bonding field. Then we prove the existence of a unique weak solution to the model. The proof is based on arguments of evolution equations with monotone operators and fixed point.
Modeling of Infantry Attacks on Real Terrain
Authors: Pincevičius A. , Baušys R. , Bekešienė S. , Kleiza V.
Published: October 2019

The estimation of the terrain features can be completely carried out by using the Geographical Information System (GIS). GIS technologies and three-dimensional map in planning battle tactics are discussed. An infantry attack on real terrain is modeled. The stochastic model of combat is given in article.
Divisibility Properties of Recurrent Sequences
Authors: Plankis T.
Published: October 2019

Let m, r ∈ N. We will show, that the recurrent sequences xn = xnrn−1 + 1 (mod g),  xn = xn!n−1 + 1 (mod g)  and xn = xrnn−1 + 1 (mod g) are periodic modulo m, where m ∈ N, and we will find some estimations of periods and pre-periodic parts. Later we will give an algorithm sophisticated enough for finding periods length in polynomial time.
Acute toxicity of the iron clathrochelate complexes
Authors: Dukhnitsky V. , Derkach I. , Plutenko M. , Fritsky I. , Derkach S.
Published: October 2019

A new class of highly valent iron compounds is formed by atmospheric oxidation in aqueous media and it is extremely stable both in solid and soluble conditions and may exist indefinitely in a medium without signs of degradation. The first clathrochelate complexes of iron (IV) are infinitely stable in water and readily available from simple, commercially available, inexpensive source materials with surprisingly mild reaction conditions. To create new drugs on their bases, research on their toxicity is required. In this study, the results of preclinical studies of a new iron clathrochelates drug are presented. Experiments were carried out on white rats and quails, which in the previous experiment were divided into five experimental and two control groups. The solution of iron clathrochelate complexes was administered intragastrically in doses 50, 500, 1000, 2000 and 5000 mg/kg, respectively. Our results have shown that there were no grounds for using rats in the advanced experiment because the conducted research has established that iron clathrochelate is non toxic to rats. Thus, the minimum dose of iron clathrochelate complexes did not cause death of quails, and the largest dose caused 100% mortality. The basic experiment was conducted on 6 groups of birds, each consisting of 7 quails. The drug was administered in the following doses: 500, 600, 700, 800, 900, 1000 mg/kg. The monitoring observation of the laboratory birds lasted for 14 days. It has been established that the average lethal dose of clathrochelate of the investigated drug for internal administration in quails is 764 ± 33 mg/kg. According to the classification of chemicals by the degree of danger (State ST 12.1.007-76), iron (IV) clathrochelate complexes correspond to the third class of hazard, and according to the classification of substances for toxicity they are classified as category 4 (low toxicity substances). The prospect of further research is to investigate the pharmacological and toxicological properties of iron (IV) clathrochelate for chronic toxicity.
Breast tumour size as a predictor of hemostatic system status and endothelial function in dogs
Authors: Bely D. D. , Rublenko M. V. , Smoyuluk V. V. , Yevtushenko I. D. , Maslikov S. N.
Published: October 2019

The high level of morbidity of dogs from mammary gland tumours and deficiencies in the pathogenesis give relevance to study of the disorders of the hemostatic system for predicting the neoplasia process. Our research concerned the determination of markers of the hemostatic system and endothelial function at different sizes (≤ 2, 5–7 and >10 cm) of benign (n = 28) and malignant (n = 27) breast tumours in dogs, taking into account their histological structure. The progression of the tumour process was accompanied by a 1.24–1.81 times increase in the fibrinogen content in the benign forms and 1.39–2.38 times in malignant against the background of progressive excess accumulation of soluble fibrin. The results of coagulation tests indicate that the increase in blood coagulation, which correlates with the magnitude of tumours, occurred mainly externally. In malignant neoplasms reliable, compared to clinically healthy dogs, reduction of total fibrinolytic activity occurred due to deficient inhibition of tissue plasminogen activator by 1.62–2.03 times. Increase in the size of benign neoplasms was accompanied by increased activity of the α1-inhibitor of proteinases, and in malignant – only in tumours of the size of 5–7 cm, against the background of its decrease in dogs with small and giant neoplasia. The progression of the disease was characterized by an increase in the content of α2-macroglobulin in benign lesions from 1.19–1.24 times, malignant – from 1.25–2.03 times. At the same time, there was a deepening of oxidative stress, as evidenced by the excess accumulation in the blood of malondialdehyde by 1.29–1.70 times in benign tumours, and 1.58–2.73 times in malignant. Regardless of the pathomorphologic form, the magnitude of the neoplasia foci is directly correlated with excess accumulation of nitric oxide and the level of hypoproteinemia, and vice versa – the content of ceruloplasmin. Further research should be undertaken to study the hemostatic status in certain nosological forms of breast tumours in dogs, which will improve the diagnosis and development of effective treatment protocols.
In silico study of peculiarities of metabolism of erythrocytes with glucosephosphate isomerase deficiency
Authors: Dotsenko O. I.
Published: October 2019

Glucose phosphate isomerase (GPI) deficiency, the third most common cause of hereditary nonspherocytic hemolytic anemia, is associated with the mutation of the GPI gene. The results of the GPI deficiency are premature aging of erythrocytes, macrocytosis, reticulocytosis, minor splenomegaly, hyperbilirubinemia and hyperferritinemia, and hemolytic crisis under the influence of exogenous oxidants such as infections or drugs. Regarding the the lack of GPI correction drugs, the theoretical substantiation of supportive therapy based on system biology approaches that would allow the analysis of the relationships between numerical metabolic processes in a cell would be beneficial. The stoichiometric model of erythrocytes’ steady state metabolism, including the pathways of Embden-Meyerhof and pentose phosphate (PPP), purine metabolism cycles and glutathione synthesis, has been developed. To predict the redistribution of metabolic flows in erythrocytes under conditions of GPI deficiency, we used the flux balance analysis (FBA). In this approach, calculations of the elementary flux modes (EFMs) and the control-effective flux (CEF) have been performed. Using the CEF evaluation approach, effective profiles of enzymatic reactions depending on the degree of enzyme deficiency were obtained. It has been shown that these relationships can be the basis for future experimental studies. Analysis of the profiles of enzymatic reactions of metabolic networks suggests that erythrocytes are capable of metabolizing other substrates that contribute to overcoming the effects of energy stress in the case of enzymopathies. So, it is shown that erythrocytes can effectively use SAM and adenosine as alternative energy sources. It has been established that the GPI enzymopathy results in a decrease in the flow through the glycolysis and pentose phosphate pathway, resulting in a decrease in the content of such reducing agents as NADPH and GSH, ATP. The processes of the GSH synthesis from amino acids in the cell are shown to be suppressed. Decreased content of NADPH and GSH cause the premature aging of erythrocytes. The target therapeutic approaches that influence the behaviour of the metabolic network of erythrocytes are discussed.
Aristotle and Iranian Ethicists
Authors: Mahallati Mohammad Jafar Amir
Published: October 2019

From Aristotle to the end of the Middle Ages, friendship was considered to be a core notion in Western political philosophy. However, as Von Heyking and Avramenko argue, friendship has lost its prominent politico-philosophical status in the modern era, particularly in the Western liberal tradition. In the Muslim tradition, and specifically in the history of Iranian thought, friendship as a moral paradigm went through a different course of development. In this article, I will present a comparative view of friendship as reflected in the works of Aristotle and three major Iranian ethicists: Ab? ?Al? A?mad Miskawayh (d. 1030), Ab??l-Q?sim ?usayn al-R?ghib al-Isfah?n? (d. ca. 1108) and Na?ir al-D?n ??s? (d. 1274). I will examine friendship-related perspectives rooted in the Irano-Islamic philosophical traditions that represent a significant but overlooked dimension of Iranian cosmopolitanism valuable for modern peacemaking approaches beyond such concepts as: “justice before peace,” “liberal peace” and “cold peace.”
Fearing the Night
Authors: Mansoori Naveed
Published: October 2019

Transnationalism in Iranian Political Thought: The Life and Times of Ahmad Fardid, by Ali Mirsepassi. Cambridge University Press, 2017. 408pp., Hb. £62.99, ISBN-13: 9781107187290; Pb. £19.99, ISBN-13: 9781316636473.
Análisis de señales cromatografícas provenientes de muestras de orina, para el análisis de cáncer de próstata usando procesamiento de señales.
Authors: Torres-Flórez Ronald de Jesús , Mendoza Luís Enrique , Nieto-Sánchez Zulmary Carolina
Published: October 2019

La temprana detección del cáncer de próstata es de vital importancia para la puesta en marcha del tratamiento del paciente. Espor ello que este artículo demuestra que las señales cromatográficas provenientes de muestras de orina tienen relación con enfermedadesrelacionadas con la próstata del hombre. En este trabajo se usaron técnicas matemáticas tales como: SVM y RNA con el fin de extraer y verificarel patrón encontrado en cada señal cromatográfica. El algoritmo fue entrenado con 10 señales de cromatografía provenientes de muestras deorina, de las cuales 7 fueron obtenidas de los grupos de pacientes de control, y 7 de pacientes enfermos. La obtención de resultados positivosllevó consigo la aplicación de técnicas de pre y procesamiento sobre las señales de cromatografías, entre las que se encuentran, recorte de zonade interés, filtrado y corrección de línea base; cuyo propósito de aplicación permitió la búsqueda de los patrones característicos propios de cadagrupo de pacientes, debido a la presencia o no presencia de células anormales o cancerígenas en la próstata. El sistema fue validado haciendouso de datos ciegos y el resultado se contrastó con el medico experto en el área, permitiendo de este modo llegar a conclusiones puntuales. Laespecificidad del software fue del 92.86%, índice obtenido en la validación del software, cuyas señales ingresadas provienen de muestras deorinas de los pacientes analizados, pero diferentes a las utilizadas para el entrenamiento.
Nivel de calidad de los procesos de gestión humana en la Universidad Mariana de Pasto.
Authors: Ordoñez-Erazo Katherine Vanessa , Rodríguez-de los Ríos María Catalina , Cabrera-Gómez Claudia Carolina , Herrera-Santacruz Juan Pablo
Published: October 2019

La investigación tuvo por objetivo general determinar el nivel de calidad en los procesos de Gestión Humana, como parte delproceso diagnóstico que lleve a la implementación de un modelo de gestión humana por competencias; se realizó una identificación delcumplimiento de los requisitos legales, de acuerdo a la norma ISO 9001, un reconocimiento de los requisitos específicos los cuales son aquellosestablecidos por la Universidad y aquellos requisitos implícitos los cuales son la percepción que los trabajadores tienen acerca de la forma enque se ejecutan los procesos de gestión humana que realiza la Universidad.Esta investigación se abordó desde el paradigma cuantitativo, con un enfoque empírico analítico de tipo descriptivo, utilizando unarecolección de datos basada en la medición, la cual tiene como objetivo principal brindar descripción completa y detallada acerca del nivel decalidad de los procesos de Gestión Humana, elaborando una construcción de modelos estadísticos y cifras para explicar la realidad con el fin derecoger información medible y posteriormente analizable.La muestra estuvo constituida por con una población de 716 trabajadores a quienes se les aplicó unos instrumentos elaborados por lasinvestigadoras; como son encuestas de percepción acerca de los requisitos implícitos para los trabajadores del área administrativa como adocentes y dos listas de chequeo al área de Gestión Humana para verificar aquellos requisitos legales como específicos.Como resultado se encontró que en la Universidad los requisitos legales están en un nivel de calidad medio, los requisitos específicos seencuentran en un nivel de calidad bajo, y por últimos aquellos requisitos implícitos tienen un nivel de calidad medio. Llevando a la Universidaden cuanto a los procesos de Gestión Humana a modo general a un nivel de calidad bajo, lo que implica que se debe realizar un análisis ymejoramiento de cómo se están empleando cada uno de los procesos.
Beneficios de los programas de ayuda al empleado (EAP) en el contexto organizacional.
Authors: Flórez-Garay Alexander , Rozo-Sánchez Astrid , Gutiérrez-Suárez Carlos
Published: October 2019

El presente artículo realiza una revisión de literatura sobre investigaciones realizadas en organizaciones que implementanprogramas de ayuda al empleado (EmployeeAsistanceProgramme - EAP). Para el cumplimiento de dicho objetivo se abordó una metodologíacualitativa, con diseño bibliográfico de tipo documental. Se concluye que los EAP contemplan beneficios para el empleado y para laorganización, relacionados con el bienestar laboral y el aumento de productividad.
A sensitive and label-free electrochemical impedance immunosensor for CDH 22 biomarker detection based on organo-functional silane modified ITO electrode
Authors: AYDIN Elif Burcu
Published: October 2019

Bu çalışmada, anti-CDH 22 antikoru ve CDH 22 antijeni arasındaki spesifik immüno-reaksiyona dayanan, kadherin benzeri protein (CDH 22) biyobelirtecinin tespiti için yeni bir elektrokimyasal etiketsiz immünosensör üretilmiştir. Geliştirilen immünosensör, anti-CDH 22 antikorlarının 3-siyanopropiltrimetoksisilan (CPTMS) ile modifiye edilmiş ITO substratı üzerinde immobilizasyonu ile oluşturulmuştur. Anti-CDH 22 antikorlarının CPTMS silanizasyon ajanına etkili bağlanması, morfolojik karakterizasyon (Taramalı Elektron Mikroskobu (SEM), Atomik Kuvvet Mikroskobu (AFM)) ve elektrokimyasal karakterizasyon (Elektrokimyasal İmpedans Spektroskopisi (EIS), Siklik Voltammetri (CV) kullanılarak incelendi. Optimum deney koşulları altında, ITO / CPTMS ile modifiye edilmiş elektrot, anti-CDH 22 antikor bağlanması için iyi bir bağlayıcıydır. Ek olarak, CPTMS modifiye elektrot CDH 22 antijen tespiti için etkili bir yüzey sunmuştur. İmmünosensör, geniş bir lineer tespit aralığı (0.03-3 pg / mL) ile düşük tespit limiti (9 fg / mL) ile sahipti. Ayrıca, iyi tekrarlanabilirlik, mükemmel tekrarlanabilirlik ve uzun depolama kararlılığına sahipti. Ek olarak, önerilen immünosensörün pratik uygulanabilirliği, insan serum numuneleri kullanılarak araştırıldı. İnsan serum numuneleri geri kazanım sonuçları (% 99,16 -% 101,94) önerilen biyosensörün doğruluğunu göstermektedir. Sonuç olarak, CPTMS, biyosensör yapımı için umut verici bir platform olabilir ve bu önerilen immünosensör gerçek insan serum analizi için uygulanabilir.
Phenomenon of Boundary in Determination of Innovative Potential of Personality
Authors: Terekhova Tatiana
Published: October 2019

On the basis of theoretical analysis of the scientific psychological literature, the article defines the phenomenon of the boundary in determining the innovative potential of the personality, The author identifies that the qualitative originality of the boundary phenomenon demonstration in determining a high level of the innovative potential of the personality is associated with such individual psychological characteristics as value orientations, creativity, temporary competence, desire for self-actualization, need for cognition, spontaneity. The single direct link to synergy is made at the low level of IPP. The «boundary» allocation at the high and low levels of IPP allows to differentiate the groups of relationships of the certain personal qualities and indicators of the personal innovative potential. By characterizing the existence of the close statistically significant links between the individual and personal characteristics of respondents with an integral indicator of the innovative potential of the personality, it is made possible to compile a psychological portrait of the innovator. The art of defining the «boundary» becomes actual by establishing the interrelationships of these individual psychological characteristics with the features of the manifestation of the innovative potential of the personality.
Legal Basis of Collection Activity in the Russian Federation
Authors: Osipova Marina
Published: October 2019

This article considers the legal regulation of collection activities in the Russian Federation. The author carries out the comparative study of the existing regulatory framework on this issue and, on this basis, the author identifies the legal status of collection agencies in Russia. The author also analyzes the application of the norms of the noted legal act on collection activities in practice which results revealing its gaps. In the course of the study, legal conflicts are identified, which arise in connection with the existing contradictions in the law. In its final clauses, the article gives an assessment of the new normative legal act in general.
Comparative and Legal Study of Registries of Unscrupulous Participants of Competitive Procedures Regulated by Federal Laws «On the Contract System in the Sphere of Purchase of Goods, Jobs and Services for Providing the State and Municipal Needs», «On Purchase of Goods, Jobs, Services by Certain Types of Legal Entities», as Well as by the Land, Housing and Forest Codes of the Russian Federation
Authors: Tishchenko Alexander
Published: October 2019

This article carries out a comparative legal analysis of the Russian institutions of registers of the unconscientious participants of the competitive procedures conducted within the contractual system in the sphere of purchases to provide the state and municipal needs, purchases made by the certain types of legal entities, as well as housing, land and forestry legislation. The author comes to the conclusion about their conceptual unity, their inseparable relationship with the competitive procedures, the emergence of which is a stage in a market economy development, the impossibility of an undubitable definition of the legal nature of the institutions under consideration, as well as the presence of certain differences and contradictions in their legal regulation, the existence of which is not based on objective reasons. The author proposes to improve the current policy management of the institutions under consideration in order to exclude the differences that are not caused by the peculiarities of the regulated relations, as well as to bring the regulatory and legal framework to a conceptual unity; he provides the substantiation for such proposals.
«Fight against Inflation» and Problem of Investment Process in Our Country
Authors: Makarova Galina
Published: October 2019

The article examines the fact of chronical investment crisis in the real sector of the Russian economy and considers the main directions of anti-inflation policy of the Central Bank of Russia (CB) which exert downward pressure on the investment process in the country (understated amounts of the money supply that do not provide the real needs of the commodity circulation; almost non-regulated spillover from real sector into the financial gambling; non-working function of the banking system in transformation of savings into investments; ambiguity of the CB status and an increased level of ambiguity for Russian investors; mass closing of domestic commercial banks and stimulation of the inflow of foreign ones; lengthy ignorance of of possibilities of using emission means of financing investment processes in the country). The article gives acritical estimation of the success gained by CB in fight against inflation during the crisis period of 2013-2017. It examines two possible scenarios of CB activity reorganization depending on possible evaluations of this activity by the Russian government.
Features of Applying by Staff of Internal Affairs Bodies Separate Measures of Ensuring Procedures in Cases of Administrative Offenses
Authors: Soshin Aleksey , Samsonov Viktor
Published: October 2019

At the present time, an analysis of legal regulation and the practice of using administrative coercive measures by law enforcement agencies is gaining ground, as sound enforcement of the norms of administrative legislation is important in identifying the degrees of efficiency, implementation of goals and measures of ensuring the procedures in cases of administrative offences, as well as the general state of legality in the field of public administration. In spite of the fact that the police officers are authorized to apply various measures of ensuring the procedures in cases of administrative offences, the most high-demand ones are examination of motor vehicles, banishment from motor vehicle driving, alcohol testing, medical alcohol testing. Compliance with the procedural order of application of the specified measures, correct drawing up procedural documents, is a guarantee of an objective examination of the case of administrative offence and bringing the law-breaker to responsibility established by the law. At the same time, the sphere of application of the measures noted observes both certain drawbacks of the acting administrative legislation and imperfection of law enforcement practice, which hinders implementing the goal of maintaining legitimacy in the sphere of public administration.
Study of Peculiarities of Psychological Readiness for Professional Activity of Personalities in University Educational Space
Authors: Vorontsova Evgenia
Published: October 2019

The article deals with the issues of psychological readiness for personal professional activity; the concept, structural elements and understanding of the category of psychological readiness for professional activity in the activity-based, system, regulatory, dynamic psychological approaches. It presents a description of studying the features of psychological readiness for professional activity of the personality carried out on the basis of FSBI of HE Angarsk State Technical University. The study is built on the assumptions that the psychological readiness of the first and second year students has not been sufficiently formed and has dynamic and structural features of the components. The dynamic structure is a complex of characteristics: motivational, adaptive, cognitive and evaluative ones. The features of the psychological readiness for activity consist of availability of significant relations between the customary directionality and the evaluative component, the motivational component and the evaluative one, the high level of socio-psychological adaptation, developed practically in equal dozes by business-related and customary directionality.
Pharmacoeconomic Analysis of Medicines Consumption in the Multisectoral Hospital
Authors: Sukhodolov Alexander , Spasennikov Boris , Sannikov Anatoliy , Varakina Zhanna , Popova Olga
Published: October 2019

The article examines the results of complex pharmacoeconomic study of antibacterial therapy rationality in a multisectoral hospital. In the current difficult financial environment of the hospital, measures were taken to optimize spending on medicinal products in the twenty-four-hour departments, in particular on consumption of germicides as one of the most significant parts of medicines expenses. The authors made an item-by-item analysis of expenses in three most cost-intensive departments and, following on from the results of the АВС-analysis, they developed a strategy and a plan of measures of expenses optimisation on antibacterial preparations.
An Icon - the Art of Traditions
Authors: Alyoshina Elena
Published: October 2019

The article examines the main issues faced by artists who want to do icon painting, who undertake writing icons and restoring temples. A brief overview of the activities of Irkutsk artists represents the directions by which iconography is developing in our region. It is emphasized that the canonicity of icon painting does not contradict the creative character of modern artistic culture and is a necessary condition for the work of Irkutsk icon painters.
International Cooperation through Academic Projects: Are There Any Future Prospects?
Authors: Bobrova Ekaterina , Kitova Elena
Published: October 2019

Today, international academic cooperation of universities is going through a tough period due to political and economic challenges. The authors consider the main causes of this and show how the situation could be improved through the development of local academic programs, such as LEADER Project. This joint educational project, focused on entrepreneurship and management skills, is arranged by Richard Ivey School of Business, University of Western Ontario (Canada). The program has 11 years of positive experience at Baikal State University in Irkutsk and it has proved to be successful and viable. The article provides analysis of the projects strengths and the main components of its success. Attention is also drawn to the specific features and potential advantages of using the case method as a modern teaching procedure, as well as to the innovative format of the project and its mutually beneficial character. The authors analyze the results of a feedback survey of the participants and instructors in order to find out their takeaways from the project, its possible drawbacks and future development prospects. The key conclusions refer to the importance of retaining international academic contacts.
Comparative Analysis of Average Monthly Real Pay of Corporate Employees in Irkutsk Oblast in Terms of Types of Economic Activity
Authors: Baldynova Evgeniia , Malyutina Svetlana
Published: October 2019

The rate of salary and remuneration as monetary compensation for labour depends on many factors that can be combined into the following groups: territorial, organizational and legal, gender, professional and educational, etc. The article examines the dependence of the average monthly real wage on the type of economic activity. In addition, the authors study the dynamics and degree of variation of the average monthly real wages in terms of types of economic activity in Irkutsk Oblast. Having analyzed the real average monthly wages by types of economic activity, the authors categorized them into several groups according to their scale.
Substantiation and Modeling of Effects from the Implementation of Industrial Policy in the Context of Techno-Economic Paradigm Shift
Authors: Svetnik Nataliia
Published: October 2019

After the recent economic crises, a necessity for industrial policy developing became obvious both for developed and developing countries. In 2014 Russia adopted a Fundamental federal law on industrial policy, but there are however a number of problems to be solved, such as an assessment of the impact of the implementation of industrial policy alternatives. In the author's opinion, the solution of these problems can be based on the concept of techno-economic paradigm shift. Using the correlation and regression analysis, the dependence of GDP on the development of high-tech industries was studied on the example of technologically advanced countries (USA, China, and Japan) and also Russia. The study was conducted in the absence of developed tools and limited statistics which could provide an indirect basis for assessing the impact of techno-economic paradigm on economic growth and well-being of the population. The author concludes that of the three examined indicators, the high-tech export is the most representative. It can thus be recommended as one of the criteria for assessing impact evaluations of the implementation of industrial policy, which can meet the challenges of scientific and technological progress at the shift of techno-economic paradigms.
Legal Pluralism, uBuntu and the Use of Open Norms in the South African Common Law of Contract
Authors: Du Plessis Hanri Magdalena
Published: October 2019

In this article, a comparison is drawn between the role of good faith in the development of the Roman law of contract and the emerging role of ubuntu in the South African common law of contract. Firstly, it is shown how the Romans realised that their existing formal and rigid laws could not address the changing legal needs of the community due to the influx of foreigners (especially foreign traders) into Rome. In reaction to the changing commercial environment, they introduced flexible legal procedures and a more normative approach to these legal transactions to achieve fairness and justice between the contracting parties. This worked so well that the new flexible procedures and normative principles were transferred to the existing formalistic law. Gradually the existing ius civile became subject to a more normative interpretation in the interests of justice through the use of the open norm of good faith. It is argued that in a similar way, ubuntu can be used to address legal pluralism in the South African legal system, and its application as an underlying constitutional value could result in the better use of the open norm of good faith to address contractual unfairness.
Adoption and evaluation of the Doha Agreement Classification system of groin pain in athletes (part 1): a modified Delphi study among the founding expert group v1
Authors: MP Heijboer Willem , Weir Adam , Delahunt Eamonn , Hölmich Per , G Schache Anthony , L Tol Johannes , de Vos Robert-Jan , Vuckovic Zarko , Serner Andreas
Published: October 2019

IntroductionDiagnosing groin pain in athletes is challenging due to the close proximity of multiple anatomic structures, the lack of a golden reference standard, and the widespread use of different terminology for similar conditions. These issues were highlighted in a previous Delphi study whereby 23 groin pain experts had poor inter-rater agreement on the suspected diagnosis in two clinical cases. These experts provided 18 and 22 different potential diagnoses for each case, respectively. This 2014 Delphi study provided an initial step towards the “Doha Agreement meeting on terminology and definitions in groin pain in athletes”. During the consensus meeting, 24 international groin pain experts with different professional qualifications aimed to address the problem of heterogeneous terminology. The experts agreed upon a clinical classification system with three major subheadings: (1) defined clinical entities for groin pain (adductor-, inguinal-, iliopsoas-, and pubic-related groin pain); (2) hip-related groin pain; (3) other causes of groin pain. A clinical classification system was preferred, since the clinical relevance of imaging has yet to be fully clarified, especially in instances of longstanding groin pain. Five years have passed since the Doha Agreement meeting, and the recommended terminology is now frequently referenced in research articles. However, it is unknown if clinicians use the classification system in clinical practice and if there is a need to further refine the recommended taxonomy. Insight into the current use of the Doha agreement terminology in both research and clinical practice from groin pain specialists could help to further improve it. Therefore, the aims of this two-stage Delphi study are to: 1) determine if the experts who participated in the Doha Agreement meeting now use more uniform terminology when diagnosing groin pain in athletes, 2) ascertain whether experts change their initial diagnosis of groin pain in athletes when they are subsequently presented with medical imaging reports, 3) evaluate to what extent the clinical classification system and associated terminology have been adopted by the experts, 4) ascertain the thoughts of the experts about any required amendments to the current clinical classification system and associated terminology, and 5) quantify the level of agreement amongst the experts of any proposed amendments to the current clinical classification system and associated terminology.
Mowiol mounting media v1
Authors: Economo Michael
Published: October 2019

This makes a low cost mounting media that preserves many fluorescent dyes very well. It is a non-hardening media. This protocol first published in Cold Spring Harbor Protocols.
Transfection of Micromonas commoda CCMP2709 v2
Authors: Sudek Lisa , Worden Alexandra , Ares Manny
Published: October 2019

This protocol describes the transformation of the picoprasinophyte alga Micromonas commoda, a green alga that is found in tropical to temperate oceans. The strain used was genome-sequenced in (1). The original strain name was NOUM17, housed as RCC299. The latter was rendered axenic, genome-sequenced, and deposited at the CCMP (now NCMA) as CCMP2709 and also maintained in the Worden lab. The below protocol is an adaptation of transformation methods used for the choanoflagellate Salpingoeca rosetta. We are grateful to N. King and D. Booth for their invaluable support in initial stages of experiments, as well as help from H. Igel, C. Poirier, M. Hamilton, S. Sudek, K. Hoadley, C. Eckmann and especially C. Yung throughout the entire development.
Electrode cleaning solution v1
Authors: Economo Michael
Published: October 2019

How to make a cleaning solution for cleaning silicon probes
FISH-CLEM hybridisation v1
Authors: Thomas Jahn Martin
Published: October 2019

The majority of environmental microorganisms remains uncultivated and are commonly referred to as microbial dark matter. Here we present our protocol for fluorescence in situ hybridization-correlative light and electron microscopy (FISH-CLEM) that enabled the identification of poribacterial cells in sponge tissue at electron microscopy resolution. This method allows to combine -omics approaches with spatial studies and should thus be applicable in the wider context of microbial ecology.
Fostering Learner Autonomy among Pre-Service EFL Teachers: A Mixed-Method Study
Authors: Öztürk Gökhan
Published: October 2019

This study reports on the process how pre-service EFL teachers developed as autonomous learners during a 14-week period in a Turkish higher education context. The participants included 25 freshman pre-service teachers, 11 males and 14 females, studying at an English language teacher education program of a state university. A course, specifically designed to improve students’ autonomy was taken by the participants and multiple forms of data collection tools were employed throughout the study. The Autonomous Learning Scale (ALS) developed by Macaskill and Taylor (2010) was used at the beginning and the end of the course, the participants were asked to write reflection reports and they were also interviewed at the end of the process. The findings demonstrated a significant change in the autonomy level of participants, specifically a dramatic change in their independence of learning. Besides, it was found that being more aware of the self, taking charge of their own learning and changing perspectives towards the notion of learning were the biggest gains of the process for the participants. In line with literature, the findings were discussed and several suggestions were made on how to integrate autonomy practices into teacher education programs.
Bioethics in the Context of Legislative Framework and Law Enforcement (Euthanasia)
Authors: Momotov V. V.
Published: October 2019

The article is devoted to one the most acute issues of bioethics, namely, the issues of legal approaches to euthanasia. The institute of euthanasia is commonly investigated in ethical and philosophical contexts. However, there is no any comprehensive legal research of the issue under consideration. Due to the fact that the Russian Federation public order prohibits euthanasia, the study is based on comparative analysis of legal and historical resources, as well as case law of the European Court of Human Rights. The author represents the general historical review of development of approaches to the institute of euthanasia.
“Judicial Convention” as a New Stage in the Recognition and Enforcement of Foreign Judgments
Authors: Zasemkova O. F.
Published: October 2019

In May 2018, at the 4th and final meeting of the Special Commission of the Hague Conference on Private International Law, the draft Convention on the Recognition and Enforcement of Foreign Judgments in Civil and Commercial Matters that had been developed since 1992 was represented. It is expected that after the Diplomatic Session that will be held in the mid-2019 the draft will be finalized and the Convention will be adopted and opened for signature.

In this regard, the article attempts to analyze the main provisions of the draft Convention and assess the appropriateness for the Russian Federation to access it, taking into account the fact that Russia has a limited number of international treaties permitting recognition and enforcement of foreign judgments in Russia and decisions of Russian courts abroad. Based on the results of the analysis, the author concludes that the adoption of this Convention will provide for a simple and effective basis for the recognition and enforcement of foreign judgments eligible for States with different legal, social and economic circumstances. This, in turn, will increase the practical value of court decisions ensuring the most comprehensive protection of the rights and interests of the party in whose favour the decision has been made and, as a consequence, will contribute to the attractiveness of this method of dispute resolution for parties involved in cross-border private law relations.

However, the mixed attitudes of the EU and the USA to the Draft Convention raises the question of their accession to the future Convention and may significantly reduce the impact of the adoption of the document under consideration.
Grounds and Criteria for Criminalization of Sexual Harassment in Labor Relations
Authors: Arzamastsev M. V.
Published: October 2019

Sexual harassment in the workplace has now become a significant social problem and, as a result, criminal legislation in many countries has included provisions prohibiting it. In our country, despite the change in moral standards of permitted forms of sexual behavior, the legislator has not yet implemented the requirements of the Council of Europe Convention On preventing and combating violence against women and domestic violence (CETS No. 210) (Istanbul Convention). The existing system of criminal law prohibitions does not effectively protect the individual from sexual harassment committed in the sphere of labor relations. Among the varieties of such acts not prohibited by the criminal law the author names the inducement to the actions of a sexual nature (associated with not the use of service dependencies, but regular contacts within the framework of labor relations); physical contact (touch), not conditioned by the nature or content of work, while not forming signs of sexual assault and causing physical pain; verbal or nonverbal abuse of a sexual nature; sexual harassment (harassment); other mental effects of a sexual nature. As shown by the analysis, these forms of deviant behavior has sufficient social danger, and the relative prevalence for their criminalization. The minimum harm from sexual harassment in the workplace is the negative impact on the psyche of the victim (both women and men), the degree of such impact due to the long-term nature of the labor realtions also becomes quite significant. In order to prevent excessive criminalization and reduce the risk of unjustified criminal prosecution, it is proposed to introduce a ban with the so called administrative prejudice, which implies the incurrence of administrative responsibility for sexual harassment in the workplace, and incurrence of criminal one — only for repeated actions of a person previously subjected to administrative punishment.
Yeni Tanı Almış Çölyak Hastalarında Tanı Anında Karaciğer Fonksiyon Testlerinin Analizi
Authors: BENGİ Göksel , DURAN Yakup
Published: October 2019

Giriş ve Amaç: Tedavi almayan çölyak hastalığında karaciğer anormallikleri sıktır. Çölyak hastalığı direkt karaciğer hasarı yapabileceği gibi diğer karaciğer hastalıklarıyla da birliktelik gösterebilir. Çölyak hastalığına sahip yetişkinlerin %24-40’ında tanı anında izole hipertransaminazemi rapor edilmiştir. Ortalama bir yıl uygulanan glütenden fakir diyet hem karaciğer enzimlerini hem de karaciğerdeki histolojik değişiklikleri geri döndürebilmektedir. Çalışmamızda çölyak hastalığında tanı anında karaciğer fonksiyon testlerinin değerlendirilmesi ve transaminaz yüksekliğinin olası nedenlerinin araştırılması amaçlandı. Gereç ve Yöntem: 2012-2017 yılları arasında çölyak hastalığı tanısı alan 100 hastanın klinik bulguları, laboratuvar değerleri, duodenal ve karaciğer biyopsileri retrospektif olarak analiz edildi. Çölyak transaminitisi tanısı alan hastalarda 1 yıllık glütensiz diyet sonrası transaminaz değerleri de incelenmiştir. Bulgular: Çölyak hastalığı tanısı sırasında 36 hastada eş zamanlı olarak transaminaz yüksekliği tespit edilmiş olup klinik ve varsa histopatolojik verileri değerlendirildiğinde bunların 2 tanesinde kronik viral hepatit B, 34 tanesinde ise çölyak transaminitisi tespit edilmiştir. Ortalama aspartat aminotransferaz düzeyi 45.2±50.0 IU/L ve ortalama alanin aminotransferaz düzeyi 44.6±43.6 IU/L idi. Transaminaz yüksekliği ile demografik veriler arasında bir korelasyon saptanmamıştır (p: 0.53). Çölyak transaminitisi tanısı alan 34 hastanın 31 tanesinde 1 yılllık glÜtenden fakir diyet sonrası transaminaz değerlerinin normale döndüğü izlenmiştir. Sonuç: Yeni tanı almış çölyak hastalarında karaciğer fonksiyon testleri yüksekliği; diğer spesifik karaciğer hastalıkları dışında çölyak hastalığına bağlı olabilir ve %34 gibi sık oranda görülür. Genellikle de hastalar glütenden fakir diyet tedavisine yanıt verirler.
Treatment of patients with isoniazid-resistant pulmonary tuberculosis using an adjuvant therapy
Authors: Rakisheva Z. K. , Balasanyants G. S. , Solov’yeva N. S.
Published: October 2019

The purpose of the study was to assess the efficacy of glutamyl-cysteinyl-glycine disodium (Glu) as adjuvant therapy in patients with isoniazid resistant pulmonary tuberculosis. Methods. This was a randomized placebo-controlled blind study. The study involved 67 patients who was randomly assigned to the treatment with Glu and antituberculosis cchemotherapy (group 1; n = 23), or placebo (group 2; n = 10), or antituberculosis chemotherapy (group 3; n = 34). All patients were positive for M.tuberculosis (MBT). The treatment included a standard intensive chemotherapy in a hospital (DOTS strategy) during 5 months (2S 3–5HRZE/5RSE). Glu was administered intramuscularly in the dose of 60 mg once daily during 10 days followed by 60 mg once daily every other day during 20 days; the total course included 20 doses. Results. Single-drug resistant MBT was detected in 26.1%, 20.0%, and 8.8% of patients in groups 1, 2, and 3, respectively. Multiple drug resistance was detected in 73.9%, 77.8%, and 91.2%, respectively. Sputum conversion was achieved in 26.1%, 52.2%, and 21.7% of group 1 patients in one, two and three months of the treatment, respectively. Sputum conversion in group 2 was achieved over 3 months of the treatment only (n = 3 at 3 months, n = 4 at 4 months, and n = 2 at 5 months); two patients were still MBT-positive to the end of the treatment. In group 3, sputum conversion was achieved in 18 patients (53.0 %) at 3 months, in 6 patients (18%) at 4 months, and in 5 patients (14.7%) at 5 months; 5 patients remained MBT-positive to the end of the treatment. Median time to sputum conversion was 62, 114, and 100 days in groups 1, 2, and 3, respectively. Conclusion. The adjuvant treatment with Glu in patients with isoniazid-resistant pulmonary tuberculosis was associated with earlier sputum conversion. This strategy can shorten the duration of the intensive treatment.
Liderazgo de los docentes de formación profesional básica para la mediación escuela-empleo del alumnado con diversidad funcional intelectual
Authors: Negri Cortés María Isabel , Leiva Olivencia Juan José
Published: October 2019

Los ciclos de Formación Profesional Básica son una plataforma emergente para la formación e inserción sociolaboral de jóvenes con Diversidad Funcional Intelectual teniendo el profesorado un papel fundamental. En este sentido, el objetivo de este trabajo fue describir y analizar el liderazgo que desempeñan los docentes al actuar como dinamizadores de los procesos de mediación entre los contextos escolares y laborales. Se ha contado con una muestra incidental de 38 docentes de institutos de educación secundaria de Málaga que ofertan ciclos de Formación Profesional Básica. Los datos se han recogido a través de un cuestionario adhoc valorado por un grupo de expertos junto con cinco entrevistas en profundidad a los profesionales de uno de estos centros. Se ha aplicado análisis cualitativo a las entrevistas, así como un análisis estadístico descriptivo a los datos del cuestionario. Los resultados muestran la necesidad de asumir por parte de los docentes un liderazgo compartido que capacite al alumnado con Diversidad Funcional Intelectual en habilidades y competencias socio-personales que faciliten su acceso al empleo, y actuando como mediadores entre el ámbito formativo y laboral, concluyendo en la necesidad de potenciar una adecuada capacitación docente y de promover la flexibilización curricular y organizativa del contexto educativo.
DIEZ-GUTIERREZ, E. J. (2018). Neoliberalismo educativo. Otra educación es posible. Barcelona: Octaedro, 109 paginas, ISBN 978-84-17219-23-9.
Authors: Bausela Herreras Esperanza
Published: October 2019

DIEZ-GUTIERREZ, E. J. (2018). Neoliberalismo educativo. Otra educación es posible. Barcelona: Octaedro, 109 paginas, ISBN 978-84-17219-23-9.