bluuebunny/crossref_metadata_2025 huggingface dataset:
Tetraspanin-enriched microdomains play an important role in pathogenesis in the protozoan parasite Entamoeba histolytica
Authors: Jiang Han , Santos Herbert J. , Nozaki Tomoyoshi
Published: October 2024

Tetraspanins (TSPANs) are a family of highly conserved proteins present in a wide variety of eukaryotes. Although protein-protein interactions of TSPANs have been well established in eukaryotes including parasitic protists, the role they play in parasitism and pathogenesis remains largely unknown. In this study, we characterized three representative members of TSPANs, TSPAN4, TSPAN12, and TSPAN13 from the human intestinal protozoan Entamoeba histolytica. Co-immunoprecipitation assays demonstrated that TSPAN4, TSPAN12 and TSPAN13 are reciprocally pulled down together with several other TSPAN-interacting proteins including TSPAN binding protein of 55kDa (TBP55) and interaptin. Blue native-PAGE analysis showed that these TSPANs form several complexes of 120–250 kDa. Repression of tspan12 and tspan13 gene expression led to decreased secretion of cysteine proteases, while repression of tspan4 led to a four-fold increase in the activity of cysteine proteases in crude extracellular vesicles (EVs) fraction. Meanwhile, strains overexpressing HA-tagged TSPAN12 and TSPAN13 demonstrated reduced adhesion to collagen. Altogether, this study reveals that the TSPANs, especially TSPAN12 and TSPAN13, are engaged with complex protein-protein interactions and are involved in the pathogenicity-related biological functions such as protease secretion and adhesion, offering insights into the potential regulatory mechanisms of tetraspanins in protozoan parasites.
The Gulf and its foreign policies
Authors: Coates Ulrichsen Kristian
Published: October 2024

The nine states of the Persian Gulf and Arabian Peninsula – Iran, Iraq, Yemen and the six members of the Gulf Cooperation Council (GCC) – are bound together in a regional system but not a security community. Four major conflicts in the region since 1980 have contributed to a volatile set of relationships which feed into perceptions of risk, threat and interest, and have shaped the conduct of foreign, defence and security policy-making accordingly. Other factors, such as revolutionary upheaval, sectarian politics and the roles of non-state actors as well as external powers, have added to an already combustible mix and made it harder to reach consensus on key issues of foreign policy. This article examines the foreign policy landscape in the Persian Gulf and Arabian Peninsula and assesses a range of factors which determine the context in which measures are framed, formulated and implemented. There are two major parts to this article. An opening section argues that the myriad connections among the nine states together constitute a definable sub-regional complex, to adapt the concept developed by Barry Buzan and Ole Waever, and as evidenced by the patterns of conflict in recent decades, albeit one based on an imbalance of conventional forms of power in which three larger states coexist alongside five smaller ones with Yemen separate yet intimately linked. This leads into a second section which explores the many interconnections which have provided the contextual backdrop to the conduct of foreign policy-making in regional states over the past four decades, and which continue to resonate today. The article focuses throughout on the linkages between domestic and foreign policy and between perceptions of interest at national and regional levels as guiding factors for policy-makers in each of the states involved.
Towards a ‘study at home’ education in the Arab Gulf region: Reterritorializing the ‘study abroad’ model
Authors: Abdul-Jabbar Wisam Kh.
Published: October 2024

Drawing on the works of Deleuze and Guattari, which describe the constituent behaviour of cultural assemblages, this article argues that deterritorialization marks the twentieth-century Gulf educational landscape, which problematized Arab Gulf identity. What followed is characterized by what Gilles Deleuze describes as reterritorialization, specifically the proliferation of American and western institutions in the Arab Gulf countries. This article proposes Deleuze and Guattari’s concepts of deterritorialization and reterritorialization as lenses through which to observe and respond to the resulting Arab Gulf epistemic and identity crises that arose in part from the ‘study abroad’ model dominating twentieth-century higher education in the Gulf states. In contrast, the ‘study at home’ model becomes an example of reterritorialization, which serves as a local epistemic response to the hegemonic internationalization of education. Deleuze and Guattari’s notions of deterritorialization and reterritorialization provide helpful conceptual tools to examine the western impact on higher education and identity formation in the Arab Gulf region. These two conceptual paradigms characterize two directions in which higher education has progressed during the second half of the twentieth century and well into the beginning of the twenty-first, especially in their intellectual and identity-related aspects. How can Deleuze’s concepts help us characterize an epistemic uqdah that places Arab Gulf education between two antithetical realities: the push towards international education and a sense of adherence to tradition and culture? How does the move for the internationalization of education within the recent history of the Arab Gulf inform identity formation? This conceptual study explores the impact of internationalized education on the Gulf Arab identity from cultural and epistemological perspectives.
Terraforming Yemen: Geoeconomic imperialism, the UAE and the southern secessionists
Authors: Cole Juan
Published: October 2024

This article argues that the intervention in Yemen (2015–present) of the United Arab Emirates (UAE) exemplified a new phenomenon, of postmodern small-state imperialism enabled by globalized, extra-European capital flows. The particular tactic deployed for these imperial purposes was terraforming, which had a tangible effect on the country’s geopolitical map. It involved a complex web of ground troops, support for surrogates and mercenaries, economic investments, and strategic concentration on securing the entire Arabian Sea and Gulf of Aden littoral. This effort had the positive goal of securing westward oil exports by the UAE and of creating a marine security environment conducive to Emirati administration of the port of Aden. Especially post-2019, it is argued, the UAE did not merely opportunistically pursue its STC policy under the wings of Saudi Arabia but rather confronted its larger partner, bombing Saudi proxies at key moments and acting more like a rival than a bandwagoning ally. This Emirati enterprise was shaped by the interests of Abu Dhabi and its local proxies rather than by US or European imperialism, though it sufficiently accorded with US policy to receive no pushback from Washington.
La profundidad de Velázquez y el humanismo trascendente de Unamuno: detonantes en la pintura de
Authors: Colinas Marcos Clara
Published: October 2024

El presente artículo expone las claves de la obra artística de Toshima Yasumasa, que gira en torno a dos principales detonantes: la profundidad del pintor español Diego de Velázquez y el humanismo trascendente del pensador Miguel de Unamuno. En ellos encontró el sentido de eternidad, su vocación por el arte, y pudo forjar en su larga estancia en España aquella conexión que fue establecida entre su arte y la pintura de Velázquez, así como entre su obra y el pensamiento unamuniano, invadido del paisaje y lo existencial. En la pintura de Yasumasa se incluyen las mismas realidades que había tratado Unamuno: el simbolismo y la estela histórica de las ciudades, el apego hacia la tierra, los vínculos con las personas, el amor por la naturaleza, el sentimiento religioso, la búsqueda de lo profundo y de lo sagrado. Constantes que, de forma gradual, serán recordadas en estas páginas.
Dave Meder, el jazz y su homenaje a Miguel de Unamuno
Authors: Chabrán Rafael , Pedro Josep Ramon
Published: October 2024

El propósito del presente ensayo es indagar sobre la obra de Dave Meder, el pianista de jazz y compositor norteamericano, y relacionar su reciente obra Unamuno songs and stories con el pensamiento de célebre pensador, poeta, novelista español Miguel de Unamuno (1864-1936). Situamos la obra de Meder dentro de las adaptaciones musicales de la obra y pensamiento de Unamuno, así como las ideas sobre la música y sus amigos músicos del vasco.
In-Ovo Antiviral Activity of Hibiscus sabdariffa against Newcastle Disease Virus
Authors: Abaka AbdulAzeez Mumsiri , Hamuel James Doughari , Abdullahi Tukur Baba , Abubakar Keta Biman
Published: October 2024

Newcastle disease is a highly contagious viral infection affecting poultry and wild birds. The causative agent is Avian paramyxovirus 1 (APMV-1), causing significant economic losses despite vaccination efforts due to its high mortality rate. Hibiscus sabdariffa was identified at Modibbo Adama University Yola, and laboratory assays were performed at the National Veterinary Research Institute Vom. The study explores the antiviral effects of extracts from H. sabdariffa calyx against a virulent strain of Newcastle Disease Virus (NDV) using embryonated chicken eggs (ECE). Standard methods were employed for cytotoxicity assay, embryo infective dose 50 (EID50) determination, and therapeutic antiviral assays. Methanol was used for extraction and phytochemical analysis, revealing various bioactive compounds like cardiac glycosides, alkaloids, flavonoids, terpenes, and phenols. Toxicity assay showed cytotoxicity at concentrations over 25 mg/ml, but therapeutic antiviral assays demonstrated virus replication inhibition at concentrations as low as 5 mg/ml. These findings suggest the potential of H. sabdariffa calyx extracts as safe and effective treatments for NDV, with promising therapeutic antiviral properties. Further pharmaceutical research is recommended to explore their use in developing novel Newcastle Disease treatments.
Leaf Extract of Kentut (Paederia foetida L.) as a Preventive Measure Against Interleukin-6 Expression in the Liver of Mice in a Sepsis Model Injected with Escherichia coli
Authors: Savitri Lisa , Freitas Maria Do Carmo Da Costa , Kasimo Elfred Rinaldo , Krissanjaya Rochmad , Juwita Syntia Tanu
Published: October 2024

Kentut leaves (Paederia foetida L.) are a medicinal plant that can be used as a preventative medicine against sepsis. This plant contains secondary metabolite compounds such as alkaloids, flavonoids, triterpenoids, saponins, and other active compounds. This research aims to to determine the influence and effective dosage of Kentut leaf extract as a preventive measure against IL-6 expression in the livers of mice in a sepsis model injected with E. coli. The method used was a Completely Randomized Design (CRD). The study involved 24 white male mice divided into 6 groups. Data analysis was performed using One way ANOVA. The average values of IL-6 expression in the mouse livers for each group are as follows: KN at 7.09%±0.06; K+ at 26.36%±0.02; K- at 72.60%±0.05; PI (100mg/kgBW) at 71.04%±0.04; PII (300mg/kgBW) at 62.22%±0.02; and PIII (500mg/kgBW) at 40.92%±0.01. The research results indicate an influence of kentut leaf extract as a preventive measure against IL-6 expression in the livers of mice in the sepsis model injected with E. coli, with a significance value of 0.000 or p-value < 0.005. The effective dosage of kentut leaf extract as a preventive measure against IL-6 expression is the PIII dosage of 500mg/kg BW. The anti-inflammatory mechanism in sepsis is thought to be caused by the presence of flavonoids, alkaloids, phenolic acids, and terpenoid compounds. The most likely anti-inflammatory mechanism is believed to involve flavonoids inhibiting cyclooxygenase (COX) and lipoxygenase (LOX) enzymes involved in the synthesis of inflammatory mediators such as prostaglandins and leukotrienes, which can trigger IL-6 production.
Riscos associados à seleção de fornecedores de agroindústrias de rapaduras em Santo Antônio da Patrulha - RS
Authors: Rodrigues Sacha Killes Cachoeira , Corrêa Ricardo Gonçalves de Faria , Baierle Ismael Cristofer , Espindola Juliana da Silveira
Published: October 2024

A globalização econômica e aumento das incertezas a nível local e nacional apontam que as cadeias de suprimentos estão cada vez mais complexas e vulneráveis a riscos. Este trabalho busca identificar os elos da cadeia produtiva das agroindústrias de rapadura localizadas no município de Santo Antônio da Patrulha, Rio Grande do Sul, e mapear os principais riscos da sua cadeia de suprimentos para estabelecer critérios associados à seleção de fornecedores. Para tal, foi realizada uma pesquisa exploratória de abordagem qualitativa, utilizando-se da pesquisa bibliográfica e coleta de dados das agroindústrias por entrevista estruturada. O método multicritério MOORA foi utilizado para avaliar a relevância dos riscos na seleção de fornecedores. Os resultados mostraram que pontualidade na entrega e qualidade são os critérios mais importantes. Os critérios de maior influência para o amendoim, principal matéria-prima, são qualidade e conformidade com as especificações e legislações. Além disso, evidencia-se uma preocupação com disponibilidade e recebimento, comum a todas as matérias- primas, fazendo com que as agroindústrias busquem fornecedores que tenham bom histórico de atendimento, minimizando os riscos de produção. Para embalagens, prioriza-se qualidade e velocidade na hora da compra. O preço não aparece como fator de destaque em nenhuma categoria. Essas evidências indicam onde focar ações para que os riscos não afetem ou afetem em menor intensidade as agroindústrias do setor.
Implementação do software Manufacturing Execution System
Authors: Sodré Leandro Barboza , Hamdan Yuri Dias , Moretto Bianca Fogaça , Piran Fabio Antonio Sartori
Published: October 2024

A indústria moveleira brasileira desempenha um papel importante na economia do país, sendo responsável pela fabricação de móveis em pequena, média ou grande escala. Esse segmento é o sexto maior produtor de móveis do mundo e exporta para 172 países em cinco continentes. Mesmo assim, a indústria moveleira brasileira enfrenta desafios em relação à sua competitividade global. Um desses desafios é a adaptação à Indústria 4.0, que traz novas tecnologias como a Internet das Coisas (IoT), Impressão 3D (Três Dimensões), robótica avançada, Big Data e Inteligência Artificial (AI). Essas inovações possibilitam vantagens como o acompanhamento de dados em tempo real, automatização e integração de processos, aumentando ainda mais a produtividade. O MES (Manufacturing Execution System) é um software amplamente adotado em vários segmentos para gerenciar os processos produtivos no chão de fábrica. O objetivo deste estudo é criar um método para a implementação do software MES na indústria de móveis, dada a escassez de pesquisas acadêmicas e a demanda por soluções tecnológicas na área moveleira. Utilizou-se a Design Science Research (DSR), esta metodologia busca solucionar problemas e melhorar o ambiente de aplicação através da criação de artefatos, contribuindo assim para o avanço do conhecimento em tecnologia e ciência. A implementação do MES (Manufacturing Execution System) resultou em melhorias na geração de relatórios de paradas de máquinas, aumentando a precisão das informações e diminuindo o tempo de geração, proporcionando a oportunidade para um aumento na eficiência operacional.
FAKTOR-FAKTOR YANG MEMPENGARUHI PAJAK DAERAH KOTA SEMARANG
Authors: Aji Firman Bayu , SBM Nugroho
Published: October 2024

Taxes are a source of regional income. Semarang City in terms of PAD has tax revenues that are still volatile. Judging from the existing tax potential, the City of Semarang has quite good potential but has not been explored effectively and efficiently. This study aims to analyze the factors that affect Semarang City local taxes with the independent variables of PDRB, inflation, number of industries and population density.The data used in this research is secondary data. The analysis model used is multiple linear regression analysis. Multiple linear regression analysis using the classical  assumption  test  includes  normality  test,  multicollinearity  test, autocoleration test, heteroscedasticity test, and hypothesis testing through the F test, t test and coefficient of determination (R2).The results of the analysis of this study indicate that the GRDP and inflation variables have a significant positive effect, while the number of industries and population density variables have a positive and insignificant effect. The analysis of the F test results shows that the variables of GRDP, inflation, population density and the number of visitors to tourism objects simultaneously influence local tax revenues. The Adjusted R square value of 87 percent of the independent variable can affect government revenue, while 13 percent of local tax revenue is influenced by variables other than the variables used in the study.
ANALISIS VALUASI EKONOMI DALAM UPAYA PENINGKATAN KUALITAS RUANG TERBUKA HIJAU DI KOTA SEMARANG (Studi Kasus : Taman Indonesia Kaya)
Authors: Fitra Fitra , Sasana Hadi
Published: October 2024

The study of the Taman Indonesia Kaya case study aims to: (1) identify people's perceptions  of  the  existence  of  RTH  Taman  Indonesia  Kaya,  (2)  estimate  the economic value of the availability of RTH Taman Indonesia Kaya, (3) analyze the factors that affect the willingness to level of Willingness To Pay (WTP) visitors towards improving the quality of RTH Taman Indonesia Kaya. Primary data and secondary data are used to calculate the WTP value. Primary data were obtained from 62 respondents using Accidental Sampling and key persons. Secondary data were obtained from relevant agencies. Descriptive statistical analysis is used to answer the first aim of this research, in-depth interview is used to the second aim of this research and the Contingent Valuation Method with the Bidding Game technique is used to answer the third aim of this research.The results of the research using questionnaires showed the perception of visitors  to  Taman  Indonesia  Kaya,  respondents  rated  quite  good  and  had  the potential to be developed with an average value of 6.5 out of 10 on all criteria. The results of the Contingent Valuation Method show that there are 90.32% who are willing  to  pay  (Willingness  to  Pay),  with  an  estimated  total  WTP  value  of  Rp.396,833,500 per year. All of the community’s willingness (WTP) factors have a significant effect, except for marital status. Based on these results, it can be used as a reference for the development strategy of Taman Indonesia Kaya and further development in efforts to increase Green Open Space in Semarang City.
ANALISIS PENGARUH MITIGASI RISIKO LIKUIDITAS DAN PENYALURAN KREDIT TERHADAP PERTUMBUHAN EKONOMI DAN STABILITAS HARGA INDONESIA TAHUN 2010.1 – 2019.4
Authors: Qinthara M. Naufal , SBM Nugroho
Published: October 2024

This  study aims  to  analyse  the  transmition  nonetary  policies  are  able  to encourage the economy and how their effects on price stability in the short and long term. This study uses secondary time series data   of mitigating the risk of liquidity, credit,  GDP,  and  inflation  of Indonesia  from 2010Q1 to 2019Q4.  The hypothesis testing of this research used the Vector Error Correction Model.Based on the results of the VECM estimation, there is a negative and significant relationship  between the Secondary  Reserve Requirement  on GDP.  However, the interbank money market variable  has a positive effect on GDP in the long run. The volume of bank lending has  a positive effect on GDP,  but can  turn around  to be negative in the long run. In addition,  with inflation as the dependent variable,  the Rupiah interbank money market has a negative and significant effect on inflation in the short and long term. the interbank foreign exchange money market has a positive relationship  to inflation in the long run and the level of bank lending has a positive effect on inflation in the short and long term.
Work-Life Balance Terhadap Pegawai Bank Studi Fenomenologi Pada Bank Setia di Yogyakarta
Authors: Hartono Evanea Setiadewi , Perdhana Mirwan Surya
Published: October 2024

Kesibukan antara pekerjaan dengan mengurus pemenuhan kebutuhan pribadi seringkali menjadi masalah. Keseimbangan kehidupan-kerja menjadi penentu antara keseimbangan diantara keduanya. Keseimbangan kehidupan-kerja mengukur bagaimana seseorang dapat mengatasi permasalahan yang dialami oleh seorang pekerja. Pegawai bank di Yogyakarta adalah salah satunya yang memiliki masalah tersebut. Tujuan Penelitian ini untuk menguji dan menganalisis bagaimana karyawan bank mengatur antara keseimbangan kehidupan dan pekerjaan para karyawan di Bank Setia di Yogyakarta. Metode Penelitian ini menggunakan metode kualitatif dengan pendekatan fenomenologi dan menggunakan Interpretative Phenomenological Analysis (IPA). Jumlah partisipan peneliti adalah 8 partisipan pegawai bank. Lokasi penelitian adalah di bank Setia di Yogyakarta. Hasil dari penelitian adalah pegawai bank seperti memiliki dua dunia yang berbeda ketika harus berhadapan dengan dua kehidupan tersebut, yakni antara menyelesaikan urusan pada kehidupan pekerjaan dan mengurus berbagai hal pada kehidupan pribadinya. Masing-masing kehidupan tidak serta merta dapat mengisi satu sama lain, karena keduanya telah memiliki porsinya masing-masing untuk dijalankan.
ANALISIS DAMPAK PANDEMI COVID-19 TERHADAP NERACA PERDAGANGAN DI KAWASAN ASIA TAHUN 2020
Authors: Wahyuningsih Heva Nofi
Published: October 2024

This study aims to determine the extent of the impact of Pandemic Covid-19 on the trade balances of countries in the Asian Region. Furthermore, the independent variables used in the study include real exchange rates, gross domestic product, pandemic covid-19 and interaction of pandemic covid-19 with gross domestic product. Pandemic Covid-19 variable uses the number of positive confirmed cases of this virus. The dependent variable in the study is the trade balance. The data used are secondary data obtained from the World Bank, Financial Data & Economic Indicators (CEIC) and Trading Economics, covering 30 countries in the Asian Region for the period I-IV year 2020. This study uses the balanced panel data method with the fixed effect model (FEM). The research used the estimation technique of fixed effect model (FEM), which was selected based on the result of the Chow and Hausman test. The results show that Pandemic Covid-19 affects the aggregate supply side, namely production activities in a country due to mobility restrictions, so that the level of output produced will experience a decline. When the level of output in a country decreases, it will have an impact on the level of demand for goods and services demanded by people abroad. Pandemic Covid-19, real exchange rate and gross domestic product variable had a negative effect on the trade balance. If there is an increase of pandemic covid-19 cases, it will later affect on the decrease of ecport activities. Likewise, if there is an increase on gross domestic product and real exchange rate, it will later affect on the increase of import activities. This negative affect will result a deficit in trade balance.
PENGARUH IPM, PERTUMBUHAN EKONOMI DAN PENGANGGURAN TERHADAP KEMISKINAN KABUPATEN/KOTA DI PROVINSI JAWA TENGAH TAHUN 2017-2019
Authors: Handayani Nuraeni
Published: October 2024

Central Java Province is a province with a poverty rate percentage that ranks second in Java after DIY, but the poverty rate in Central Java Province is still quite high because it is still above the national poverty rate. This study aims to analyze the effect of the Human Development Index (HDI), economic growth and unemployment rates in districts/cities in Central Java Province in 2017-2019.Based on the data used, in this study using panel data regression analysis with the fixed effect method which was tested using the Eviews 9.0 application. The data used in this study is secondary data. The independent variables used in this study are the Human Development Index (HDI), economic growth and unemployment rates, while the dependent variable used is the poverty rate in 35 regencies/cities in Central Java Province in 2017-2019.The results of this research that the Human Development Index (HDI) had a positive effect on the poverty rate in districts/cities in Central Java Province in 2017-2019. Variables of economic growth and unemployment had no significant effect on the poverty rate. The variables of the Human Development Index (HDI), economic growth and the unemployment rate together have a significant effect on poverty in Central Java Province in districts/cities in Central Java Province in 2017-2019. Keywords: poverty, human development index (HDI), economic growth, unemployment rate
ANALISIS PENGARUH PERTUMBUHAN PENDUDUK, TENAGA KERJA, INVESTASI, DAN INFLASI TERHADAP PERTUMBUHAN EKONOMI KABUPATEN/KOTA DI PROVINSI JAWA TENGAH TAHUN 2015-2019
Authors: Martadinata Mochammad Adrian
Published: October 2024

Economic growth is having a role in reflecting the success of the development of a region, economic growth itself is the increase in goods produced by economic actors at a certain time where this behavior is carried out to carry out economic activities. This economic activity which later makes a profit so that it becomes the capital to carry out other activities such as development which includes starting from social, economic and cultural issues as a whole. Economic growth is also a reflection that government policies are running properly and should be the targets that must be achieved in a certain period which is usually five years. The purpose of this study is to analyze the effect of population growth rate, labor, investment value and inflation rate on economic growth in Central Java Province city or district. The analytical tool used is OLS from 2015 to 2019.The results of the study explained that the variables that affect economic growth in Central Java Province city or district have different effects where the number of population growth has a positive and significant effect, labor has a positive and insignificant effect, investment has a positive and insignificant effect, and inflation has a negative and negative effect. not significant.
PENGARUH PENDAPATAN ASLI DAERAH (PAD) DAN ALOKASI DANA DARI PUSAT TERHADAP TINGKAT KEMISKINAN DI PROVINSI DI YOGYAKARTA TAHUN 2015-2020
Authors: Lindrianti Nur Fita
Published: October 2024

DI Yogyakarta Province is a province with the highest percentage of poverty in Java. This study aims to analyze the effect of Regional Original Income and Fund Allocation from the Center which consists of General Allocation Funds, Special Allocation Funds, and Revenue Sharing Funds on the poverty level in the Province of DI Yogyakarta in 2015-2020. Based on the data, This research is using panel of data after testing on Eviews 12.0, The most precise analysis is using panel data regression method. This research is using secondary data which consist of The real income profit, general fund, allocation fund, and sharing profit of 5 districts / city in Yogyakarta province 2015 - 2020. The result of this research is the allocation fund has positive effect on the poverty level, while the Regional Original Revenue, General Allocation Fund and Revenue Sharing Fund had no significant effect on the poverty level. Keyword : Poverty, the real income in districts, allocation fund, the special allocation income, sharing profit
ANALISIS PENGARUH AGLOMERASI INDUSTRI, JUMLAH PENDUDUK TERHADAP TINGKAT DISPARITAS PENDAPATAN ANTAR KABUPATEN/KOTA DI PROVINSI JAWA TENGAH TAHUN 2016-2020
Authors: Chrisetyoningrum Agnesa Marytha
Published: October 2024

This study aims to determine the level of inequality between regencies/cities in Central Java Province, and the influence of industrial agglomeration, population on income disparities in Central Java Province.            The data used in this study is secondary data from the Central Statistics Agency (BPS) 2016-2020. The analytical method used is descriptive and regression. Regression analysis using panel data. Economic disparities are calculated by the Williamson Index. The effect of industrial agglomeration and population on income disparity was analyzed using linear regression fixed effect model.            The Williamson index value for all districts/cities shows economic inequality that occurs in low criteria, except for Brebes district with moderate criteria. Industrial agglomeration variables and population have a simultaneous effect on income disparities in Central Java Province. Keywords: Economic Disparity, Industrial Agglomeration, Population
Analisis Pengaruh Inklusi Keuangan, Inflasi dan GDP per Kapita Terhadap Stabilitas Sistem Keuangan di Negara Berkembang Asia Pasifik
Authors: Wahyuningtyas Sri
Published: October 2024

Financial inclusion has an important role in financial system stability. Limited access to financial srvices is an obstacl for the community to access formal financial institutions so that financial inclusion is needed to realize a financial system that is more efficient and accessible to the public.            This study aims to analyz the effect of financial inclusion, inflation and GDP per Capita on financial system stability in developing Asia Pacific countries. This study uses quantitative descriptive analysis, where descriptive analysis describes the conditions of financial inclusion in each country using the Financial Inclusion Index. In the quantitative analysis, panel data regression method will be used using the FEM model.             The results of the analysis show that both financial inclusion and inflation have a significant positive effect on financial system stability, while GDP per Capita has no effect on financial system stability.
The Effect of Education Level, Health Level, and Income Inequality on Regency/City Poverty Level in West Sumatra Province 2016-2021
Authors: Putra Eko Pratama , Robertus Mulyo Hendarto
Published: October 2024

The poverty rate in the province of West Sumatera is still high, the poverty rate can be seen in the statistics of the province of West Sumatera. This study analyzes several factors that influence the level of poverty in the province of West Sumatera. This study aims to analyze the effect of education level, health level and income inequality on poverty in districts/cities in West Sumatera Province in 2016-2021.This study uses panel data from 2016 to 2021 with a research sample of 19 cities / districts in West Sumatera Province. The analysis used in this research is the Fixed Effect Model (FEM) approach using Least Square Dummy Variable (LSDV).The panel regression model used in this study has tested classical assumptions, detected no multicollinearity, autocorrelation, heteroscedasticity, and normally distributed data, with an R-squared of 0.97. Based on the partial research that affects the level of poverty, namely the level of education and the level of health. Income inequality does not affect poverty levels. If viewed simultaneously or together, these variables can affect the level of poverty. Suggestions that can be submitted are that the government pays attention to the level of education, the level of public health. To the community to realize the importance of education and health in order to reduce the level of poverty. Keywords : Education Level, Health Level, And Inequality, Income Against Poverty Level
Pengaruh Literasi Keuangan, Pendapatan dan Technology Acceptance Model (Tam) Terhadap Minat Penggunaan Quick Response Indonesian Standar (QRIS) pada Pelaku UMKM di Kecamatan Temanggung
Authors: Kresna Rangga Bayu , SBM Nugroho
Published: October 2024

QRIS is a payment instrument officially issued by Bank Indonesia to be used in daily payment transaction activities by the public. MSMEs are an important sector in the use of QRIS as a transaction tool. However, MSMEs in Temanggung District have not fully used QRIS as part of their payment transaction activities. There are many factors that cause these problems to occur including financial literacy, income, and the basic concepts of the Technology Acceptance Model (TAM), namely perceptions of usefulness and perceptions of ease in applying interest in using QRIS. This study aims to analyze the effect of variables related to these problems, namely financial literacy, income, perceived usefulness, and perceived ease of use on interest in using QRIS for SMEs in Temanggung District. This research uses multiple regression analysis methods in empirical testing. The data used are primary data obtained from distributing questionnaires using a Likert scale, with the subject of active MSMEs in Temanggung District. This study uses the SPSS 26.0 application as an analytical tool. From the results of the analysis carried out, this study shows that the financial literacy variable has a significant influence on the interest in using QRIS. The income variable has no significant effect on interest in use. Variables of perceived usefulness and perceived ease of use also have no significant effect. The variables of financial literacy, income, perceived usefulness, and perceived ease of use simultaneously have a positive and significant effect. Of these variables, financial literacy has the greatest influence on interest in using QRIS. Therefore, the government needs to pay attention to and strengthen policies, especially in the field of financial literacy as the main factor in increasing the interest of MSMEs and the public in using QRIS as a means of payment transactions.
Pengaruh Penggunaan Dana Desa dalam Bidang Pembangunan Desa dan Bidang Pemberdayaan Masyarakat Desa Terhadap Kemiskinan Desa di Kabupaten Pemalang Tahun 2019-2020
Authors: Sundarti Sofa , Robertus Mulyo Hendarto
Published: October 2024

Poverty is a problem faced by all countries. Both developed countries, but the problem of poverty is more common in developing countries. One of the reasons for the problem of poverty in developing countries is that development conditions in developing countries are still unstable. To overcome this, the government implements a fiscal decentralization policy with a village fund program which is expected to be able to reduce poverty. The priorities for using village funds include village development and village community empowerment, for this reason the purpose of this study is to analyze the effect of the realization of village funds used in the field of village development and in the field of village community empowerment in every village in Pemalang Regency in 2019 to 2020.Ssecondary data by using the selected Fixed Effect (FE) method, the dependent variable used in this paper is village poverty and two independent variables, namely the realization of village funds in the field of village development and the realization of village funds in the field of empowerment of rural communities with the research population of all villages in Pemalang Regency. This uses purposive sampling method to determine the sample used in the paper.The results of this indicate that the independent variable simultaneously has no effect on village poverty, while partially the variable realization of village funds in the field of village development has a negative value with a coefficient value of -0.362448 and a probability value of 0.0824 which means the realization of village funds in the field of village development, it has an effect on reducing the amount of village poverty but is not significant, while the realization of village funds in the field of village community empowerment has a partially negative significant effect on rural poverty with a coefficient value of -0.358970 and a probability value of 0.0000 which means that each the addition of 1 million realizations in the field of village community empowerment was able to reduce the number of poor people by 36 people
Hubungan Antara Produk Domestik Regional Bruto dan Pengangguran di Provinsi Jawa Tengah Tahun 2011-2020
Authors: Zunaida Rosita Alfiansyah , Robertus Mulyo Hendarto
Published: October 2024

Labor is one of the indicators used to see the development and economic conditions of a region. Economic growth and the growth of the Labor Force are traditionally considered as one of the positive factors that spur economic growth. Central Java Province is one of the provinces in Indonesia which in 2020 through the 2020 Population Census has a total population of 36,516,035 people, occupying the third position among the provinces in Indonesia with the highest population. With the population increasing every year, the number of unemployed also increases because the labor force cannot be absorbed into the available jobs. The  value of labor absorbed in an economic sector can describe the workforce that is included in the labor force that is able to be absorbed by economic sectors. The relationship between GRDP and unemployment is explained through Okun's Law. Okun's law states that for every 2 percent decrease in GRDP related to potential GRDP, the unemployment rate increases by about 1 percent so it can be concluded that the unemployment rate has a negative relationship with GRDP growth.The method used in this study is panel data regression method using the REM model. The data used in this study is data on the GDP and unemployment of Central Java Province in 2011-2020.The result of this research is that the GRDP variable has a positive relationship to the unemployment variable. This is not in line with Okun's Law which explains that the relationship between GRDP and unemployment has a negative relationship. So it can be concluded that Okun's Law cannot be applied in cases in Central Java Province.  Keywords: GRDP, unemployment, Okun's Law, Random Effect Model (REM)
Pengaruh Belanja Pemerintah Bidang Pendidikan, Kesehatan dan PDRB Terhadap IPM di Provinsi Jawa Tengah (Studi Kasus 35 Kab/kota Provinsi Jawa Tengah)
Authors: Prastiwi Sindhu Ayu Triadita , Handayani Herniwati Retno
Published: October 2024

The current focus of development is more on human development. Through improving the quality of human resources, it can improve social welfare and state development. For this reason, the government is trying to improve the quality of human development through budget allocations in the health and education sectors which continue to increase every year. The purpose of this study was to analyze the effect of government spending on education, health, and gross regional domestic products (GRDP) on the human development index in 35 districts/cities of Central Java province in 2014-2019. The type of data used is secondary data in 35 districts/cities in Central Java from 2014-2019. The analysis method used in this research is panel data regression using Fixed Effect Model (FEM) with Generalized Least Square (GLS) weighting. The results in this study are the  health spending and GRDP variables have no significant effect on HDI, while the education spending variable has a significant effect on HDI.
Analisis Pengaruh PDB Perkapita, Pengeluaran Pemerintah dan Pengangguran Terhadap IPM di Negara-Negara ASEAN Tahun 2009-2018
Authors: Wiguna Ardiansyah Dewa Astana , Iskandar Deden Dinar
Published: October 2024

Human Development Index (HDI) is one indicator of development progress on aspects of human quality in a country. This research aims to analyze the effect of PDB percapita, government expenditures, and unemployment against HDI in ASEAN’s countries. The analytical method used in this research is random effect model (REM). This research used secondary data in panel form containing 6 Countries at ASEAN on cross section data and 2009 until 2018 on time series data. Data processed with Eviews10. The result of this examine shows that GDP percapita and government expenditures has positive and significant effect for HDI in ASEAN. Meanwhile, unemployment are insignificant for HDI in ASEAN.
Reparametrizing the Antecedent Moisture Model
Authors:   RJN Group, Inc., Edgren David , Czachorski Robert ,   OHM Advisors, H2Ometrics, Gonwa William ,   Milwaukee School of Engineering
Published: October 2024

Developing simple and accurate hydrologic models for wet-weather sanitary sewer flow has long been enigmatic for the engineering community. Hydrologic models suitable for surface water hydrology often perform poorly when simulating sanitary sewer hydrology when they do not account for antecedent moisture conditions and seasonality. The result is underpredicting peak flow and volume in wet conditions and overpredicting the same in dry conditions. The Antecedent Moisture Model is an empirically-calibrated method which models a rainfall capture fraction that varies by antecedent moisture and season, and transforms the captured rainfall into a flow hydrograph. The Antecedent Moisture Model has been particularly successful in modeling sanitary sewer infiltration, for which other methods perform poorly. This paper suggests a reparameterization of the original model which provides virtually identical results while improving interpretability and ease of use. The reparametrized model is designed to be time step independent and more physically relatable, intuitive, and scaleable than the original parameterization while remaining functionally equivalent to the original parameterization. The paper also presents two computational examples which demonstrate the application of the Antecedent Moisture Model formulas and math.
Dietary pattern and menstrual disorders among female university students
Authors: Ahmed Gehad S. , Mohamed Lotfy Alshimaa Mohsen
Published: October 2024

Objectives

Assessment of the relationship between dietary patterns and menstrual disorders among female medical and paramedical students at Beni-Suef University, Egypt.

Methods

Beni-Suef University conducted a cross-sectional analytical questionnaire-based study. Three hundred fifty two female medical and paramedical students agreed to participate in the study. The collected data about demographics, physical activity, menstrual history, and dietary assessment were transferred to SPSS version 26 for statistical analysis. A p value ≤0.05 was considered statistically significant.

Results

The prevalence of irregular cycles, heavy blood flow, severe dysmenorrhea, and premenstrual syndrome (PMS) was found to be (21.9 %), (13.1 %), (35.5 %), and (68.9 %), respectively. Poor adherence to the Mediterranean diet (40.1 %) and physical activity (69.9 %) was present. Females with irregular cycles (p=0.472), heavy menstrual blood flow (p=0.007), and severe dysmenorrhea (p=0.029) reported lower adherence to the Mediterranean diet. Mothers’ educational level (p=0.034), family income (p=0.005), and family size (p=0.009) were significantly associated with dietary adherence.

Conclusions

Poor adherence to regular physical activity and the Mediterranean diet is highly prevalent in our research and is highly associated with menstruation disorders. So, it is critical to support health education programs emphasizing healthy dietary habits and regular physical activity to improve menstrual health and women’s quality of life.
Gly183Ser homozygous mutation of the steroid 5-a reductase type 2 (SRD5A2) gene in a Brazilian patient: case report
Authors: Laureano Daniela P. , Kirjner Vitória , Ferraro Lethicia C. , Carvalho Clarissa G. , Leite Julio César L. , Hemesath Tatiana P. , Costa Eduardo Corrêa , Guaragna-Filho Guilherme , Leistner Sandra
Published: October 2024

Objectives

Steroid 5α-reductase type 2 deficiency (5α-RD2) is an autosomal recessive disorder caused by mutations in the SRD5A2 gene. This condition is characterized by reduced enzymatic activity of the 5α-reductase type 2 enzyme. Individuals with mutations in the SRD5A2 gene may exhibit various symptoms of under-masculinization in 46, XY individuals. We conducted a comprehensive analysis of the SRD5A2 gene in a patient with disorder of sex development (DSD).

Case presentation

We describe a patient with a homozygous Gly183Ser variant in the SRD5A2 gene. Their sibling also carries this variant in homozygosity, while both parents have it in a heterozygous state. The patient presents with predominantly female traits and was raised as a girl. Although the siblings exhibit distinct phenotypic characteristics, both have assumed a male gender identity.

Conclusions

This study reveals different phenotypes for the two siblings, highlighting the complexity of establishing a genotype-phenotype correlation in the SRD5A2 gene. It is noteworthy that the Gly183Ser variant seems to be more prevalent among individuals of African descent, aligning with our patient’s ethnic background.
Ultra-compact and high-precision differential detection method based on liquid crystal polarization grating for miniature atomic magnetometer
Authors: Cui Zhibo , Wang Yuhao , Liu Ying , Jin Mingke , Sun Jie , Zhai Yueyang , Zhou Xiangyang , Chai Zhen
Published: October 2024

Atomic magnetometers (AMs) that use alkali vapors, such as rubidium, are among the most sensitive sensors for magnetic field measurement. They commonly use polarization differential detection to mitigate common-mode noise. Nevertheless, traditional differential detection optics, including polarization beam splitters (PBS) and half-wave plates, are typically bulky and large, which restricts further reductions in sensor dimensions. In this study, a combination of liquid crystal polarization grating (LCPG) and liquid crystal quarter-wave plate is used for differential detection in AMs, with magnetic field strength determined by measuring the intensity of two diffracted beams from the LCPG. The experimental findings indicate that the fabricated LCPG exhibits a circularly polarized extinction ratio of 3,656 and achieves an average diffraction efficiency of 99 %. In addition, the differential detection method based on LCPG can achieve an angular resolution of 1.48 × 10−7 rad. Subsequently, the method is employed in an AM to achieve an average magnetic sensitivity of 13.8 fT/Hz1/2. Compared to the PBS-based differential detection method, this method enhances the magnetometer response coefficient by 13 % and achieves co-side distribution of the two diffracted beams, thereby avoiding the need for additional vertical optical paths. The effective thickness of the detection optics is reduced to the micrometer scale, allowing for future integration as thin films onto microfabricated vapor cells. This study offers a practical solution for miniaturized AMs with exceptionally high sensitivity.