bluuebunny/crossref_metadata_2025 huggingface dataset:
El papel de los medios de comunicación en la construcción del relato sobre género y conflicto en Siria
Authors: Pérez del Pulgar de Válor Marta
Published: June 2020

Este artículo está enmarcado en una investigación más amplia para una tesis doctoral que busca comprender cómo los conflictos armados inciden sobre la violencia de género en sus diferentes manifestaciones. Se ahonda en los roles y responsabilidades de los diferentes actores internacionales, nacionales y locales en la implementación de la agenda de mujeres, paz y seguridad. En este entorno los medios de comunicación desempeñan un rol fundamental. El presente artículo pretende analizar cómo los medios de comunicación contribuyen a construir narrativas sobre guerras y no contemplan posibles enfoques de paz a la hora de cubrir los conflictos armados. Nos centraremos en el relato que construyen los medios de comunicación sobre el conflicto armado en Siria. En cómo los sesgos de los diferentes medios de distintas corrientes y líneas editoriales nos muestran realidades aparentemente diferentes en las que buenos y malos no son los mismos. Y en las que las mujeres son victimizadas y los estereotipos de género se perpetúan. Indagaremos en el papel que medios y periodistas desempeñan; y valoraremos si la presencia de mujeres en los medios y las corresponsalías de guerra tiene un efecto en la manera de dar cobertura a los conflictos armados y la forma en la que los medios proyectan la imagen de las mujeres afectadas por la guerra.
Ternary Echo Hiding in Echo Files
Authors: Latypov Rustam , Stolov Evgeni
Published: June 2020

We propose a new family of echo hiding procedures designed to work with audio files with ternary watermarks. Most attention is paid to the case when the image is used as a watermark. The possibility of using a melody for this purpose is also mentioned. A human is supposed to be a detector to prove the presence of a watermark in the audio file. The approach employs infinite impulse response (IIR) filters of a particular form that provides a capability insertion a few symbols into a fragment of the container. The suggested method’s payload and resistance to various attacks exceed the parameters of the classical implementation of echo hiding.
The Neurosis of Blackness and Psychological Trauma in Edward Albee's The Death of Bessie Smith
Authors: Naseef Ienas Talib
Published: June 2020

Edward Albee, as a playwright, indicates that art should be useful and have a message. Therefore, his work foregrounds and critically examines issues concerning the Neurosis of Blackness and psychological trauma. Albee uses cruelty of racism in reflecting psychological trauma and emotional abuse of American black identity in his plays. Race, social inequality, and gender still sustain to engender controversy audience consciously. Racial discrimination is one of the major issues that affect the American Society. Albee challenges and exposes the presumptive dreams of equality of American society and institutional racism. Therefore, one of the main problems of the twentieth century in America is skin color. It affects every phase of African Americans' life including self-concept and identity which are never resolved. In addition to outlining the reasons and origins of violence as a cause of white-dominated supremacy. In his, work Albee gives different insights and meanings to those elusive dreams showing that the consequences of such unfulfilled dreams are disappointment, despair, and death. The purpose of this study is to investigate the effect of psychological trauma and emotional abuse of the racial distinction in Edward Albee's The Death of Bessie Smith (1956) and its effect on the elusive dreams such the dream of turning white, liberty and equality of Afro-American.
PENERAPAN MODEL PEMBELAJARAN PROBLEM BASED LEARNING UNTUK MENINGKATKAN KEAKTIFAN BELAJAR SISWA PADA MATERI EKOSISTEM DI KOMPETENSI KEAHLIAN X OTOMATISASI DAN TATA KELOLA PERKAANTORAN SMKN 2 PENAJAM PASER UTARA TAHUN PELAJARAN 2017/2018
Authors: Susilowati Susilowati
Published: June 2020

Karakter siswa di kompetensi keahlian X Otomatisasi dan Tata kelola Perkantoran SMKN 2 Penajam Paser Utara untuk materi ekosistem sebelumnya kurang aktif dalam pembelajaran IPA Terapan, hal ini ditunjukkan dengan kurangnya respon siswa kepada materi pelajaran, siswa cenderung pasif dalam pembelajaran.  Penelitian ini bertujuan untuk meningkatkan keaktifan belajar siswa melalui penerapan model pembelajaran Problem Based Learning. Jenis penelitian ini adalah Penelitian Tindakan Kelas (PTK) yang dilaksanakan dalam dua siklus. Setiap siklus terdiri dari beberapa tahap yaitu perencanaan, pelaksanaan tindakan, observasi dan refleksi. Subjek dalam penelitian ini adalah siswa di kompetensi keahlian X Otomatisasi dan Tata Kelola Perkantoran Tahun pelajaran 2017/2018 yang terdiri atas 31 siswa. Teknik utama dalam pengumpulan data dilakukan dengan cara observasi, angket dan dokumentasi. Hasil penelitian menunjukkan bahwa pada siklus I  rata-rata prosentase keaktifan  belajar  siswa adalah 74%. Pada siklus II prosentase keaktifan belajar siswa adalah 85%.  Berdasarkan data prosentase tiap siklus ternyata terjadi kenaikan keaktifan belajar siswa. Kesimpulan penelitian ini adalah bahwa model pembelajaran Problem Based Learning (PBL) dapat meningkatkan keaktifan belajar siswa pada materi ekosistem di kompetensi keahlian X Otomatisasi dan Tata kelola Perkantoran  SMK N 2  Penajam Paser Utara, Tahun Pelajaran 2017/2018
UPAYA MENINGKATKAN KOMPETENSI GURU DALAM MENYUSUN RENCANA PELAKSANAAN PEMBELAJARAN MELALUI BIMBINGAN BERKELANJUTAN DI SMP NEGERI 23 PPU TAHUN 2018
Authors: Kusmiati Kusmiati
Published: June 2020

Penelitian ini bertujuan untuk meningkatkan kompetensi guru dalam menyusun Rencana Pelaksanaan Pembelajaran. Ruang lingkup permasalahan hanya dibatasi pada komponen-komponen RPP. Subyek penelitian sepuluh orang guru di SMP Negeri 23 PPU yang terdiri dari tiga orang guru pria dan tujuh orang guru wanita. Hasil penelitian menunjukkan bahwa terdapat peningkatan, hal itu dapat dibuktikan dari hasil observasi /pengamatan yang memperlihatkan bahwa terjadi peningkatan kompetensi guru dalam menyusun RPP dari siklus ke siklus. Pada siklus I nilai rata-rata komponen RPP 69% dan pada siklus II 83%. Jadi, terjadi peningkatan 14% dari siklus I.
PENGGUNAAN KONJUNGSI PADA PTK MAHASISWA PROGRAM STUDI PENDIDIKAN BAHASA DAN SASTRA INDONESIA TAHUN 2018 UNIVERSITAS BALIKPAPAN
Authors: Nurjanah Ike , Rahayu Sri , Maulida Nurliani
Published: June 2020

Penggunaan konjungsi sangat diperlukan untuk menjelaskan keteraturan dan kepaduan di antara kata, frasa, klausa, dan paragraf. Oleh karena itu, penggunaan konjungsi baik konjungsi koordinatif maupun subordinatif pada karya tulis ilmiah khususnya PTK sangat diperlukan. Penelitian ini bertujuan untuk mendeskripsikan penggunaan konjungsi pada PTK mahasiswa program studi pendidikan bahasa dan sastra Indonesia tahun 2018. Penelitian ini merupakan penelitian kualitatif dengan pendekatan analisis isi. Data yang digunakan dalam penelitian ini yaitu kesalahan penggunaan konjungsi koordinatif dan konjungsi subordinatif. Sumber data dalam penelitian ini yaitu hasil karya tulis ilmiah mahasiswa semester VII Program Studi Pendidikan Bahasa dan Sastra Indonesia tahun 2018 berupa PTK sebanyak 10 PTK yang dipilih menggunakan teknik Random Sampling. Pengumpulan data dilakukan dengan teknik simak catat, lalu dianalisis dengan teknik analisis deskriptif. Hasil penelitian menunjukkan bahwa penggunaan konjungsi pada PTK mahasiswa semester VII Program Studi Pendidikan Bahasa dan Sastra Indonesia diperoleh 90 kesalahan, yang terdiri dari 53 kesalahan penggunaan konjungsi koordinatif dan 37 kesalahan penggunaan konjungsi subordinatif. Kesalahan penggunaan konjungsi tersebut dapat terjadi disebabkan oleh ketidaktepatan pemilihan konjungsi dan tidak memperhatikan penempatan konjungsi. Kesalahan penggunaan konjungsi koordinatif paling banyak ditemukan pada konjungsi dan dan konjungsi sedangkan. Selanjutnya kesalahan penggunaan konjungsi subordinatif paling banyak ditemukan pada konjungsi sehingga dan konjungsi karena.
PENGARUH METAKOGNISI DAN KEAKTIFAN BELAJAR SISWA TERHADAP HASIL BELAJAR MATEMATIKA
Authors: Ulichusna Ayu Arsya , Sari Tri Hariyati Nur Indah , Susilo Ganjar
Published: June 2020

Tujuan penelitian ini adalah untuk mengetahui apakah terdapat pengaruh metakognisi dan keaktifan belajar siswa terhadap hasil belajar matematika siswa kelas VIII SMP Negeri 6 Balikpapan Tahun Ajaran 2018/2019 baik secara bersama-sama maupun secara parsial. Populasi dalam penelitian ini adalah siswa kelas VIII SMP Negeri 6 Balikpapan yaitu sebanyak 357, sedangkan sampel dalam penelitian ini yaitu siswa kelas VIII-4 dan VIII-9 sebanyak 73 siswa. Teknik sampling yang digunakan peneliti yaitu menggunakan teknik cluster random sampling. Pendekatan yang digunakan dalam penelitian ini pendekatan kuantitatif dan jenis penelitian adalah kuantitatif asosiatif. Teknik pengumpulan data yang digunakan dalam penelitian ini berupa angket metakognisi, angket keaktifan belajar siswa dan tes hasil belajar matematika. Dalam penelitian ini menggunakan uji f dan uji t, dan terdapat pengaruh signifikansi pada uji f 0,013 < 0,05, pengaruh signifikansi keaktifan belajar siswa pada uji t 0,004 < 0,05 dan tidak terdapat pengaruh pada metakognisi 0,270 ≥ 0,05.
PENGARUH PENGGUNAAN MODEL KONTEKSTUAL TERHADAP KEMAMPUAN MENULIS TEKS PERSUASI SISWA KELAS VIII SMP MUHAMMADIYAH 05 MEDAN
Authors: Simbolon Julita , Haidir Hilman , Daulay Ibrahim
Published: June 2020

Permasalahan data penelitian ini adalah (1) Kemampuan menulis teks persuasi masih tergolong rendah. (2) Rendahnya kemampuan menulis peserta didik diakibatkan model yang tidak tepat. (3) Peserta didik masih kesulitan menuangkan ide dalam menulis khususnya menulis teks persuasi. Penelitian ini bertujuan untuk mengetahui pengaruh model kontekstual terhadap kemampuan menulis teks persuasi oleh siswa kelas VIII SMP Muhammadiyah 05 Medan Tahun Pelajaran 2018/2019. Penelitian ini merupakan penelitian eksperimen dengan desain penelitian postest design. Penelitian ini menguji cobakan model pembelajaran kemudian mengetahui perbedaan penggunaannya atau meninjau pengaruh terhadap hasil belajar siswa. Populasi penelitian ini adalah semua siswa kelas VIII SMP Muhammaiyah 05 Medan Tahun Pelajaran 2018/2019 yang terdiri dari 2 kelas dengan jumlah 60 siswa. Alat pengumpulan data yang digunakan dalam penelitian ini adalah posttest design. Dari hasil penelitian dan pengelolaan data diperoleh kesimpulan ini, (1) rata-rata nilai kemampuan menulis teks persuasi siswa kelas VIII SMP Muhammadiyah 05 Medan Tahun Pelajaran 2018/2019 dengan menggunakan model konvensional adalah= 61,7 dan yang menggunakan model kontekstual adalah = 80. (2) rata-rata nilai kemampuan menulis teks persuasi oleh siswa kelas VIII SMP Muhammadiyah 05 Medan Tahun Pelajaran 2018/2019.
The Factors Affecting The Incidence Of Hyperuricemia On The Rejang Tribe In Bengkulu
Authors: Jumiyati Jumiyati , Witradharma Tetes Wahyu
Published: June 2020

The Rejang tribe is partly living on the lowland and coastal coastline, the typical Rejang cooking tradition has been assimilated into the Minang and Malay cooking traditions. Malay people like to consume foods that are fatty, dining, oily and salty.  Fish, beef, shrimp and nuts have purine content of 9-100 mg of purin/100 g of foodstuffs.  One of the factors affecting hyperuricemia is the habit of consuming purine eating, it will result in gout disease. The purpose of this research is to determine the factors that influence the incidence of hyperuricemia on the Rejang tribe in Bengkulu. Design research is cross sectional. Rejang Group's research samples numbered 64 respondents. Data collected is the result of uric acid examination, gender, age, knowledge, consumption pattern, liquid consumption, BMI. The instruments used are questionnaires, eating consumption patterns using FFQ form, weight gained by weighing with digital scales. Data analysis using Chi-Square and multivariate tests using logistic regression test
Visual analogue scale - a tool for assessing the control of allergic rhinitis
Authors: Nenasheva N M , Terekhova E P , Bodnya O S , Sebekina O V
Published: June 2020

Allergic rhinitis (AR) is the most common form of rhinitis and the most common allergic disease in children and adults. Numerous clinical studies and daily practice indicate a pronounced negative effect of symptoms of AR on patients’ quality of life, their usual daily activity, cognitive functions, mood and sleep. The type and severity of individual symptoms can vary from patient to patient, and therapy should be directed to the overall control of the symptoms of AR. It is important to obtain reliable and comparable information regarding the severity of AR symptoms before, during and after the treatment, which can be assessed using a simple and accessible tool - a visual analogue scale (VAS). VAS validated for patients with AR allows to define a controlled, partially controlled and uncontrolled AR. The article proposes an algorithm for the treatment of AR, depending on the severity of the symptoms, assessed using VAS.
Diagnostic and treatment algorithm for different phenotypes of chronic rhinosinusitis with nasal polyps
Authors: Savlevich E L , Dyneva M E , Gaganov L E , Egorov V I , Gerasimov A N , Kurbacheva O M
Published: June 2020

Chronic rhinosinusitis with nasal polyps (CRSwNP) may vary in clinical manifestations and can often be associated with a number of comorbid diseases. For a practitioner it is important to forecast the development of the disease, evaluate the risk of relapse and select the most efficient method of treatment in each clinical case. At present, there are no standardized and validated diagnostic biomarkers that could be used as predictors of CRSwNP clinical course. Purpose of the study: to develop diagnostic and treatment algorithm for varies CRSwNP phenotypes based on clinical and laboratory parameters. Materials and methods, CRSwNP patients were split into 3 groups: group 1 - CRSwNP without allergy and asthma; group 2 - CRSwNP with allergic rhinitis and/or allergic asthma; group 3 - CRSwNP with non-allergic asthma. All patients were subjected to nasal cavity endoscopy and nasal polyps biopsy, allergological examination, histological analysis of polyp stroma to detect the leukocytes infiltration and eosinophil-neutrophil index (ENI). Results, CRSwNP phenotypes show significant difference in clinical manifestations of rhinosinusitis (p
Associative relationship between atopy, HLA complex genes and other genes
Authors: Astafyeva N G , Shamgunova B A , Kobzev D Yu , Michailova I Ae
Published: June 2020

This review presents current data on the associative relationships of genes of the major histocompatibility complex (HLA) and other genes with atopy. Despite the long history of studying the role of HLA class genes in atopy and the introduction of modern technologies and methods, many unresolved issues remain, including the difficulties caused by the heterogeneity of the human population, the complex structure and disequilibrium of linkage between different HLA genes. Although phenotypic heterogeneity is considered as the main limitation in understanding the genetic determinants of atopy, only a few studies have examined the relationships of its typical clinical manifestations induced by aeroallergens with certain HLA genes. The identified molecular mechanisms and genetic characteristics open up the possibility of using new therapeutic targets and modifying existing drugs.
Hereditary angioedema: experience of substitution therapy with a C1 esterase inhibitor in the Sverdlovsk region
Authors: Beltyukov E K , Vedenskaya S S , Skorokhodov I S , Naumova V V , Beltyukova M V , Karakina M L
Published: June 2020

Hereditary angioedema (HAO) is rare disease, however, it's lifethreatening localization can be fatal. Antifibrinolytics and attenuated androgens used for the prevention of HAO attacks have side effects, which limit their use. The bradykinin B2 receptor antagonist, Icatybant is an effective but shortacting dmedication. The human C1 esterase inhibitor (berinert) is safe and effective for the prevention and relief of angioedema of lifethreatening localization, including in pregnant women. The management of patients with HAO is regulated by national guidelines, and the use of a human C1 esterase inhibitor is recommended by instruction of the drug and by the Ministry of Health of the Sverdlovsk region. Patients with HAO should be provided with patient’s passport and fill a diary of symptoms monitoring of HAO.
Tiotropium bromide: additional options for the treatment of bronchial asthma
Authors: Kurbacheva O M , Dyneva M E
Published: June 2020

Bronchial asthma (BA) is one of the most common chronic diseases, characterized by airway inflammation and bronchospasm. Symptoms of BA are wheezing, shortness of breath, a feeling of constriction in the chest and cough, the frequency and severity of which vary greatly over time. Today studies of BA phenotypes allow selecting treatment depending on the particular pathogenesis of each phenotype individually, thereby helping to achieve control, which is the main goal of BA therapy. However, it is necessary to take into account the peculiarities of airway innervation, since an increased parasympathetic tone is characteristics of all BA phenotypes and plays an important role in the development of bronchoconstriction and inflammation. Therefore, tiotropium bromide, which is a long-acting blocker of muscarinic cholinergic receptors, is one of the main bronchodilators in the treatment of BA. It blocks bronchoconstriction, hypersecretion and swelling of the mucous membrane of the airway, which in turn prevents the progression of inflammation, and the prolonged action of tiotropium bromide, which allows it to be used once a day helps to achieve control of asthma in addition to basic inhalation therapy - inhaled corticosteroids (ICS) long-acting P2-agonists (LABA). According to GINA (Global Initiative for Asthma), tiotropium bromide is recommended as an additional treatment, starting from step 4, and in accordance with the Russian Federal Clinical Guidelines for Bronchial Asthma - from step 3. Currently, according to clinical studies, much is known about the mechanisms of action and biological properties of tiotropium bromide, which made it possible to substantiate the needs for its administration to patients with BA regardless of its phenotype. This strategy will contribute to a more successful control of BA considering risk factors and comorbidity, thereby reducing needs of increasing ICS dose.
Analysis of the incidence of primary immunodeficiency disorders in the Samara region. Clinical cases
Authors: Zhestkov A V , Kozlova O S , Lyamin A V , Pechkurova A D , Zolotov M O , Kulagina V V
Published: June 2020

Research objective. This research was conducted to identify and to evaluate clinical and anamnestic features of primary immunodeficiency disorders (PID) as well as quantitive and qualitive microflora composition in PID-patients in Samara region. Methods. We analysed 29 case histories of patients with PID aged from 3 to 55 years old (20 men, 9 women). Clinical and anamnestic features of the diseases were studied. We also examined microflora of 34 loci from upper respiratory tract of 7 patients. Taking into account a small sample we used statistical analysis of variance by criterion F, the normality of the distribution was evaluated by the Shapiro-Wilk criterion (S-U), the distribution was considered normal when S-U value was
The house dust mites significance in the development of atopy
Authors: Petrova S Yu , Khlgatian S V , Berzhets V M
Published: June 2020

Background. Knowledge of the structure and particularity of sensitization in the region allows us to choose the correct tactics of treatment and prevention of atopic reactions. Objective. To study the structure of sensitization to inhalation allergens in Moscow and Moscow region since 2009 to 2017 and to determine significance of sensitization to house dust mites Dermatophagoides pteronyssinus (Der p) and Dermatophagoides farinae (Der f) in it. Methods. Blood serum of Moscow region patients with atopy (n=2546) was examined by RIDA AllergyScreen method in the period from 2009 to 2017. Results. The allergosensitisation structure was determined. It was revealed that there was no decreasing of the frequency of house dust mites (Der р and Der f) sensitization in observation period. The features of monovalent, polyvalent and combined sensitization among patients with IgE reactions to Der р and Der f were analyzed. Conclusions. According to our research 20% of patients with atopy in Moscow region have sensitization to Der р and/or Der f. The percentage of allergosensitisation to Der р is higher than to Der f. Most often house dust mites sensitization combined with pollen sensitization.
Predictors of efficacy of allergen immunotherapy in children with seasonal allergic rhinoconjunctivitis and pollen-food allergy syndrom
Authors: Makarova S G , Namazova-Baranova L S , Ereshko O A , Vishneva E A , Kogevnikova O V , Snovskaya M A , Alekseeva A A , Efendieva K E , Levina Y G
Published: June 2020

Objective of the research. To study predictors of efficacy of AIT in relation to the symptoms of seasonal ARC and PFAS in children with different IgE profiles. Materials and methods. Open prospective observational study of 161 patients aged 5 to 17 years with clinical symptoms of ARC (the annual escalation in April-May, duration of the disease is not less than 2 years, the need for symptomatic therapy in the flowering season of cause-significant plants) and PFAS for products of plant origin. The examination included skin testing, as well as sIgE determination of birch pollen allergen extract, cross-food allergens of plant origin (apple, pear, cherry, peach, carrot) and recombinant birch pollen allergens allergens (rBet v 1, rBet v 2, rBet v 4, rBet v 6) on the automatic analyzer ImmunoCAP250. All patients received two courses of AIT, sublingual administration. Assessment of efficacy was performed using the modified scheme A.D. Ado and diagnostic introduction earlier unbearable product. Conclusion. Monosensitization to rBet v 1 is a clinical and laboratory marker of the high efficacy of AIT in children with seasonal ARC and PFAS. Conclusion. Monosensitization to rBet v 1 is a clinical and laboratory marker of the high efficacy of ACIT in children with pollinosis and cross-PAS. Daily high-dose immunotherapy with standardized extract of birch pollen allergen has a good therapeutic effect, including in relation to the manifestations ofPFAS.
Features of innate immunity in children with moderate course of acute urticaria
Authors: Maltsev S V , Sizyakina L P , Lebedenko A A
Published: June 2020

Background. The prevalence of acute urticaria in children remains high. Urticaria is polietiologic disease, maintaining the homeostasis of the body is carried out by close cooperation of various parts of the immune system. The aim of this investigation was to study the features of innate immunity in children with moderate acute urticaria. Methods. To achieve this goal 71 children with moderate acute urticaria were examined. The control group included 30 healthy children of both sexes of the same age. Clinical methods of the study included disease history analysis, phisical examination of the child with determination of the degree of urticaria severity (calculation of the urticaria activity index within 7 days). Immunological methods included NK-lymphocytes, CD14+CD282+, CD14+CD284+, CD14+CD289+, serum IgE level, lactoferrin, IFN-y, IL-4, IL-6, test with NBT rate. Statistical calculations were performed in R Foundation for Statistical Computing. Results. Urticaria with undetermined causal factor happend more often, urticaria with allergic or pseudo-allergic genesis, as well as parasitic infections were established only in 17% of patients, family allergic history was found in a third of patients, in 41% of children acute urticaria proceeded with angioedema, in 9,3% of children urticaria acquired chronic course. Statistically significant increase of CD14+CD284+, decrease of CD14+CD289+, high concentrations of lactoferrin, decrease of natural killers, increase total serum IgE level in the half of the patients, low microbicidal activity with a decrease in adaptation reserves and reduced levels of IL-4, increased the content of IFN-y were found. Conclusion. The revealed changes indicate an imbalance in innate immunity, the launch of the cytokine cascade of inflammation, which is accompanied by further activation of the regulatory components of the inflammatory process in children suffering from acute urticaria.
The clinical significance of food animal allergens
Authors: Pampura A N , Varlamov E E
Published: June 2020

Animal foods products contain the most balanced complex of essential nutrients. The clinical manifestations of allergy to these products are varied. Key aspect of this problem is diagnostics and assessment of cross-reactivity. The food animal products that more often induce symptoms include cow’s milk, hen’s egg, fish, mollusks, crustaceans, mammalian meat. Data on the main classes of food animal allergens inducing the development of cross-allergic reactions as well as syndromes associated with cross-reactivity like «bird-egg», «cat-pork», «fish-chicken» and a-Gal-syndrome/«red meat syndrome» are described in this article.
Microbiome of human skin - its immunohomeostatic role and the role in pathogenesis of skin diseases
Authors: Petrunin D D
Published: June 2020

In the last decade new methods of metagenomic analysis allowed to obtain important data regarding the microbiome of human skin. The problem of colonization and secondary infection by pathogenic microbes is of special importance for allergic dermatoses that require topical immunosuppressive therapy. One of treatment options in this case could be topical multicomponent drugs that allow successful treatment of infectious complications of inflammatory dermatoses. But there are still a lot of blanks regarding both fundamental questions regarding human skin microbiome and practice aspects of treatment of skin diseases where it plays a pathogenetic role. This literature review systematizes and structures the accumulated data regarding the composition and the role of human skin microbiome in normal conditions and in various skin diseases as well as summarizes clinical data of use of combinational topical glucocorticosteroid drugs. Furthermore, some algorithms concerning the choice and optimization of topical treatment of secondary infected dermatoses are outlined.
The efficacy and safety of antihistamine therapy in school-age children
Authors: Sidorovich O I
Published: June 2020

Every year the prevalence of allergic diseases is steadily increasing. Histamine is the main mediator of allergic inflammation. Cetirizine is an effective, selective H1-receptor blocker, and drug of choice in complex treatment of various allergies among adults as well as children.
Cross-reactive food allergy to PR-10 homologues in birch pollen sensitized patients
Authors: Litovkina A O , Fedenko E S , Elisutina O G
Published: June 2020

Pollen allergy (pollinosis) is one of the most common allergic diseases. Majority of pollen allergy patients (47-70%) have a cross-reactive food allergy to fruits, vegetables, nuts and seeds. Oral allergic syndrome is the most common clinical manifestation of cross-reactive food allergy. The article presents the data on cross-reactive food allergy to Pr-10 homologues in birch pollen sensitized patients.
Current aspects of pathogenesis, diagnostics and treatment of idiopathic anaphylaxis
Authors: Esakova N V , Pampura A N
Published: June 2020

Anaphylaxis is defined as a serious generalized allergic or hypersensitivity reaction that is rapid in onset and might cause the death. In some cases, anaphylaxis occurs without a specific inducing trigger, and in this situation, after unsuccessful diagnostics, anaphylactic reaction is called idiopathic. Patients with idiopathic anaphylaxis are about 1/3 of total number of patients with lifethreatening anaphylaxis. Current data on the prevalence, pathogenesis, diagnostics and treatment of idiopathic anaphylaxis are given in the article.
Behind the Science literacy of Filipino students at PISA 2018: A Case study in the Philippines’ Educational System
Authors: Cordon Jefferson M , Polong John Domnique Benedict
Published: June 2020

Purpose of the study: To find out the struggle to build students' Science literacy experienced by the Philippines in the PISA 2018 results.

Methodology: the methodology used uses Case Study design. The method used by collecting facts from various data, learning curricula, culture and some Science discourse related to science literacy and PISA score. Various facts are analyzed by grouping and classifying and drawing conclusions from the discussion.

decision-makers Findings: integration efforts from teachers, schools, and curriculum continue to be improved by the government to improve the quality of education, although the results of the Science literacy of students in PISA 2018 have not been sufficient.

Applications of this study: This study will provide an open picture to provide innovation, a literature study for the basis of thinking the importance of overall integrase in increasing Science literacy of students, not just teachers

Novelty/Originality of this study: Cultural influences on students' science literacy.
Large Mode Area Photonic Crystal Fiber with Low Dispersion and Confinement Loss for Terahertz Wave Guiding
Authors: Liu Chao , Wang Liying , Wang Jianwei , An Sinuo , Wang Famei , Li Xianli , Liu Wei , Su Weiquan , Liu Qiang , Mu Haiwei , Sun Tao , Chu Paul K.
Published: June 2020

A photonic crystal fiber (PCF) made of the cyclic-olefin copolymer (COC) with low dispersion and confinement loss, large-mode-area, and single-mode transmission for terahertz wave guiding is described. The characteristics of the PCF in the terahertz range are simulated and analyzed by the full-vector finite element method (FEM). The effects of the structural parameters on the performance of the terahertz PCF are also investigated. The effective mode field area of the PCF is as large as 1.22084 × 107 μm2 at a wavelength of 1,000 μm and a flat dispersion of 0.07669 ± 0.33258 ps/nm/km is obtained. A much lower confinement loss of 6.0253 × 10-16 dB/m is achieved. The single mode transmission over the entire terahertz wave band is described.
Towards Sustainable Practice in the Event Industry: Insights from Practitioners
Authors: Liu Yun Qing , Lei Weng Si (Clara)
Published: June 2020

The event industry, being very wide and dynamic, is often reported in negative terms when it comes to environmental issues. In view of the serious nature of environmental issues nowadays, the authors see a pressing need to examine the current efforts being made in relation to environmental
sustainability in the event industry. This article aims to reveal the level of awareness of the environmental impact of the organization of events, the sustainable green practices that are in place in practice, and the potential improvements in environmental sustainability actions, from the
point of view of professional event planners. Qualitative in-depth interviews were conducted to collect insights from professional event planners. A total of eight event planners, with between 4 and 25 years of event planning experience, were interviewed. The interview data were transcribed
verbatim and coded to identify thematic topics for discussion. The findings are encouraging and demand attention from industry practitioners. All the respondents were well aware of the current environmental impact caused by the organization of events. Sustainable green practices are in place
in some companies, and insights into those practices were revealed. Potential improvements in sustainable green actions were examined. The education of employees and clients is identified as key for the implementation of sustainable green practices.
Albrecht Durer and the 16TH Century Melancholy
Authors: Rodrigues Marcel Henrique
Published: June 2020

Little has been discussed in academia about the close relationship between the Renaissance of the 16th century and melancholy humor, and esoteric elements arising mainly from Florentine Neoplatonism. The link between melancholy and esotericism becomes very clear when we analyze the gravure “Melencolia I” by Albrecht Dürer (1471-1528), composed of a significant number of symbols that refer to an esoteric religious culture that then emerged. Renaissance melancholy gained several nuances. On the one hand, it was considered a sin, a despicable mood characteristic of witches; on the other hand, a deep sense of inspiration typical of men of “genius”. This ambivalence also occurred in the firmament, as the melancholic people were guided by the dark planet Saturn, according to astrological belief. We also have the cultural scenario of the 16th century, especially in Dürer's Germany, which contributed to strengthening the melancholy issues.
Features of psychocorrection work with young adults who consume psychoactive substances
Authors: Tabachnikov S. I. , Kharchenko Ye. M. , Sinitska T. V. , Chepurna A. M. , Kioseva O. V. , Voronina O. V.
Published: June 2020

Background. Today our state pays considerable attention to health issues and the introduction of innovative health-preserving technologies. Of course it is the trend of deteriorating health of young people, increasing the incidence of socially dangerous diseases, including tuberculosis and HIV / AIDS, mental disorders. This increases in morbidity is due to the spread of well-known risk factors, including smoking, alcohol abuse and drug use, especially among young people. At the same time, the problem of commitment of Ukrainian students to the values of health and a healthy lifestyle remains one of the most important tasks of the educational process in the educational environment of higher education and Ukrainian society as a whole.

Objective – optimization of preventive technologies of the educational process of higher education on the basis of psycho-correctional assistance to this contingent.

Materials and methods. The identification of the risk group was made using the indicators of AUDIT-like tests, the values of which were in the range of 16-19 points, conditionally represented the risk group for the development of addictions.

Results. The research according the indicators and forms of aggression showed that people with who use psychoactive substances tried to show their personal traits, characterized by the presence of destructive tendencies in interpersonal relationships, aggressive behavior of psychological characteristics manifested by such traits, as fear of public disapproval, irritability, tendency to see hostility in others actions, the conviction of addicts that they can not be masters of their own destiny, the tendency to feel shame and guilty in many situations. Helplessness, dependence, the need for help from the side of others, the desire to solve the problem of dependence “with other people’s hands” were also revealed. It was established that one of the dominant features of the person of addicts is infantilism, which is presented in impulsiveness, egocentrism and dependence on other people.

Conclusions. Thus, in general, the proposed system of psychological correction provided the opportunity to obtain a high and lasting effect – to adequately change the stereotype of psychoactive substances, to eliminate emotional and volitional disorders, to improve social adaptation in 55 (33,6%) of students who used psychoactive substances.
Facilitating the "Elite" in innovation acquisition
Authors: NEWNHAM Denise Shelley
Published: June 2020

Innovation is a term that features in more than 40 000 web searches. Innovation is often confused with other terms such as creativity. Scott (2012) maintains that creativity is only part of the process of innovation. Educating the youth for tomorrows' world requires harnessing innovative measures where theoretical concepts are woven into the practical every-day (Newnham, 2015; Virkkunen, Newnham, Nleya & Engeström, 2012; Miettinen, 2005, 2009) and that of our tomorrow land. Christensen and Overdorf (2000) developed the concept of disruptive innovations. They state that disruptive innovations are derived from disruptive technologies. Disruptive innovations are those that have a new use or exchange value (Ollman, 2003) and eventually disrupt an existing practice and its value network.Whilst developed nation states attempt to contend with the disruption of ICT's use in learning spaces, developing countries attempt to catch up to the international models of education.Morocco's education mission and vision has not produced the desired outcomes and a new coalition with USAID had been drawn up until 2020. New strategies are being designed to overcome existing problems such as levels of illiteracy, dropout rate and student motivation. This text explores the possibilities of innovative models of education and provides concrete suggestions from noted scholars in the field.
Rigid altitude building parameters and their determination during monitoring
Authors: Плотников Алексей Николаевич , Иванов Михаил Юрьевич , Яковлева Ольга Станиславовна
Published: June 2020

В статье рассматриваются вопросы, связанные с соотношением жесткостей горизонтальных и вертикальных элементов высотных зданий. Из учета принципов работы несущих систем таких зданий определены характерные точки перелома кривой упругой вертикальной линии. Проанализирована возможность применения керамзитобетона в перекрытиях с точки зрения влияния их жесткости на деформации всей системы. Для различных конструктивных систем выполнен расчет перемещений от ветровой статической нагрузки с учетом пульсационной составляющей ветровой нагрузки, а также сопоставление компьютерного и ручного расчета. Определены места расположения датчиков автоматического мониторинга.

The article discusses issues related to the ratio of the stiffnesses of horizontal and vertical elements of high-rise buildings. Based on the principles of operation of the load-bearing systems of such buildings, the characteristic fracture points of the elastic vertical line curve are determined. The possibility of using expanded clay in floors is analyzed from the point of view of the influence of their rigidity on the deformation of the entire system. For various structural systems, displacements from the static wind load were calculated taking into account the pulsating component of the wind load, as well as a comparison of computer and manual calculations. The locations of automatic monitoring sensors are determined.
Báo cáo các ca bệnh tim ba buồng nhĩ trái ở trẻ em tại Bệnh viện Trung ương Huế
Authors: Thái Việt Tuấn
Published: June 2020

SHORT REVIEW OF COR TRIATRIATUM IN CHILDREN AT HUE CENTRAL HOSPITAL

Cor triatriatum is a rare congenital cardiac anomaly in which the left atrium is divided into two compartments by an abnormal fibromuscular septum with an opening, producing varying degrees of obstruction of pulmonary venous return. During 7 years from 2012 to 2019, we met 5 cases of children with Cor triatriatum. All of them addmited with dyspnea, a loud S2 and a nonspecific systolic murmur. The patients were correctly diagnosed by echocardiography and successfully operated.
Keywords: Cor triatriatum, congenital cardiac anomaly
Nhân một trường hợp bệnh Malt lymphoma dạ dày
Authors: Nguyễn Thanh Ái
Published: June 2020

CASE STUDY: GASTRIC MUCOSA-ASSOCIATED LYMPHOID TISSUE (MALT) LYMPHOMA

Extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue (EMZL-MALT) have been linked to chronic immune stimulation due toinfection or autoimmune stimuli.The causal association between Helicobacter pylori(HP) and gastric MALT lymphoma has been well demonstrated. HPeradication with antibiotics has emerged as the standard therapy for early stage HPpositive gastric MALT lymphoma.High response rates and long-term survival have been reported inpatients with localized gastric MALT lymphomatreated with low-doseradiationtherapy.Monoclonal antibody and chemotherapy are reserved forpatients failing or recurring after RT and those with advanced stage disease.
Key words: mucosa-associated lymphoid tissue, gastric lymphoma
Báo cáo trường hợp: xoắn tử cung đang mang thai 25 tuần trên sản phụ có hai tử cung tại Bệnh viện Trung ương Huế
Authors: Châu Khắc Tú
Published: June 2020

Case report: Uterine torsion in pregnant woman of
25 gestational week- age with 2 uterus at Hue Central Hospital

Uterine torsion in pregnancy is a rare but very dangerous complication. The diagnosis of uterine torsion is often difficult due to the rare occurrence of this complication and unspecific clinical symptoms. A pregnant woman of 25gestational week came to our hospital with a severe abdominal pain, very strong uterine contraction and dead fetus. Urgent cesarean section surgery is performed with a diagnosis of severe placental abruptionand the malformation of uterus didelphys. During the caesarean section, we found the pregnant uterus on the right siteand the right appendage twisted 180 degrees to the left. The patient was untwisted, undergone the incision in the low part of the uterus to take the dead fetus out, and had a subtotal hysterectomy and rightoophorosalpingectomy after unsuccessful attempt to preserve the uterus. The postoperative condition was stable and the patient was discharged after 5 days.
Keywords: Uterine torsion, pregnancy
Nghiên cứu mối liên quan giữa nồng độ ima (Ischemia modified albumin) và mức độ tổn thương động mạch vành ở bệnh nhân hội chứng vành cấp
Authors: Phạm Quang Tuấn
Published: June 2020

RESEARCH THE CORRELATION BETWEEN IMA CONCENTRATION AND DEGREE OF CORONARY ARTERY LESIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME

Introduction: Coronary artery lesions were the main cause of ACS, the character of coronary artery lesion and how is IMA concentrations correlated with degree of coronary artery lesion in acute coronary syndrome?
Objective: Survey character of coronary artery lesions in patients with acute coronary syndrome through the results of angiography and correlation between the concentration of IMA and degree of coronary artery lesions in patients with acute coronary syndrome.
Subject and Method: 130 patients at the Cardiology Center-Hue Central Hospital are diagnosed acute coronary syndrome according to the Fourth universal deﬁnition of myocardial infarction 2018. In which 103 patients were taken angiography and evaluated the coronary artery lesions follow GENSINI scale.
Result: Research conducted on 130 patients, including 85 males and 45 females with the proportion of male: female is 1.89, average age: 65.7 ± 12.3years old. There are 91.3% of patients with coronary artery lesions higher than coronary artery non lesions (p <0.001). Injury of one branch accounted for 35,9%, two branch accounted for 34.0% and three branch injuries accounted for 21.4%.. There are 79.6% in LAD injury and 58.3% in RCA, accounting for 41.7% in LCx. The lesions stenosis that more than 75% is accounted for the highest percentage 70.59%. GENSINI score average is 27.80 ± 25.92 and median score is 21 points. There is no correlation between the concentration of IMA and the branching coronary lesions with r = - 0,046, p > 0.05. There is no correlation between the concentration of IMA and GENSINI scores with r = - 0,064, p> 0,05.
Conclusions: LAD lesions accounted for the highest percentage, lesions more than one coronary artery branch also high percentage and severe coronary stenosis is highest proportion in acute coronary syndrome.
There is no correlation between the IMA concentration and the number of branching coronary lesions, as well as GENSINI scores.
Key words: IMA, Coronay artery lesions, ACS.
FINANCIAL SITUATION OF PRE-PACKED INSOLVENCIES
Authors: Schönfeld Jaroslav
Published: June 2020

This paper is focused on the financial situation of companies entering insolvency proceedings.
It does not work with all kinds of the insolvent companies, but this paper concentrates on one specific issue. The issue
is pre-pack insolvencies. The main aim is to show if the financial situation is an important factor for consent to pre-pack.
The pre-pack insolvencies are insolvency cases which start with an insolvency proposal which is accompanied by a reorganization
plan already approved by creditors. Prepacks should help make the insolvency process quicker and enable enterprise financial
rehabilitation and sustain the going concern principle. On the other hand, the procedure can hardly be successful when the
financial situation of the company is extremely poor. Therefore this paper evaluates the financial situation of the companies
with pre-packed insolvency in the Czech Republic. The analysis of companies was conducted over one, two or three year periods
prior to the companies entering an insolvency proceeding. According to the literature, financial indicators used for evaluation
are commonly EBITDA, cash liquidity, debt ratio, ROA and the Altman Z-Score prediction model. Results for the individual
enterprises are summed up in this paper using basic descriptive and variable statistics. Conclusions have especially practical
implications because they show financial inability of majority pre-packed cases.
Information Content of JWST NIRSpec Transmission Spectra of Warm Neptunes
Authors: Guzmán-Mesa Andrea , Kitzmann Daniel , Fisher Chloe , Burgasser Adam J. , Hoeijmakers H. Jens , Márquez-Neila Pablo , Grimm Simon L. , Mandell Avi M. , Sznitman Raphael , Heng Kevin
Published: June 2020

Warm Neptunes offer a rich opportunity for understanding exo-atmospheric chemistry. With the upcoming James Webb Space Telescope (JWST), there is a need to elucidate the balance between investments in telescope time versus scientific yield. We use the supervised machine-learning method of the random forest to perform an information content (IC) analysis on a 11-parameter model of transmission spectra from the various NIRSpec modes. The three bluest medium-resolution NIRSpec modes (0.7–1.27 μm, 0.97–1.84 μm, 1.66–3.07 μm) are insensitive to the presence of CO. The reddest medium-resolution mode (2.87–5.10 μm) is sensitive to all of the molecules assumed in our model: CO, CO2, CH4, C2H2, H2O, HCN, and NH3. It competes effectively with the three bluest modes on the information encoded on cloud abundance and particle size. It is also competitive with the low-resolution prism mode (0.6–5.3 μm) on the inference of every parameter except for the temperature and ammonia abundance. We recommend astronomers to use the reddest medium-resolution NIRSpec mode for studying the atmospheric chemistry of 800–1200 K warm Neptunes; its corresponding high-resolution counterpart offers diminishing returns. We compare our findings to previous JWST IC analyses that favor the blue orders and suggest that the reliance on chemical equilibrium could lead to biased outcomes if this assumption does not apply. A simple, pressure-independent diagnostic for identifying chemical disequilibrium is proposed based on measuring the abundances of H2O, CO, and CO2.