bluuebunny/crossref_metadata_2025 huggingface dataset:
Use of Technology and Its Association With Academic Performance and Life Satisfaction Among Children and Adolescents
Authors: Ramírez Saray , Gana Sofía , Garcés Soledad , Zúñiga Teresa , Araya Ricardo , Gaete Jorge
Published: November 2021

Introduction: In the last years, there has been a rise in the use of technology among children and adolescents, which has led to a greater concern about its impact on their socioemotional and cognitive development.

Aims: To explore the time spent using technology, the risk perception of its use by students, and the association between frequency of technology use and life satisfaction and academic performance among children and adolescents in Chile. Additionally, we explored the mediating effect of sleep deprivation on these outcomes.

Methods: This is a cross-sectional study, where 2,440 students (9-12 years old) from 13 schools participated. Data was collected using an online survey answered by students during school hours. The association analyses were performed using multivariable regression models considering life satisfaction and academic performance as dependent variables. Additionally, mediating analyses were conducted using structural equation modeling.

Results: Time watching television and using cellphones were similar on weekdays, and playing video games was the most frequent activity during weekends. A 42.1% of students reported playing online video games with strangers, and 12.7% had sleep deprivation. Lower self-reported academic performance was associated with cyberbullying victimization, sleep deprivation, being hacked, exposure to violent content, time spent using cell phones during weekdays and weekends, and playing video games during weekdays. Students who perceived that playing video games after 9 pm affected their sleep had a higher academic performance. There was a clear mediating effect of sleep deprivation in the relationship between time spent using a cellphone during weekdays and weekends and playing video games during weekdays and GPA.

Conclusions: Time spent using technological devices was not associated with life satisfaction; however, the time spent using cell phones and playing video games was related to lower self-reported academic performance, mediated by sleep deprivation. Future research may focus on a better understanding of the mechanisms involved in the effect of technology use on sleep routines among adolescents and potential interventions to reduce its impact on academic performance.
Psychological Distress Among Healthcare Professionals During the Early Stages of the COVID-19 Outbreak in Low Resource Settings: A Cross-Sectional Study in Bangladesh
Authors: Hossain Md. Riad , Patwary Muhammad Mainuddin , Sultana Rabeya , Browning Matthew H. E. M.
Published: November 2021

The COVID-19 pandemic has been very destructive to and compromised the functioning of all nations' public health systems. In the absence of a vaccine, healthcare workers have been employed to relentlessly fight against COVID-19. The psychological status of healthcare workers during the pandemic in countries with limited resources, notably Bangladesh, remains unclear. The present study aimed to investigate the psychological states of frontline and non-frontline Bangladeshi healthcare workers during the early stages of the COVID-19 outbreak. An online cross-sectional study was conducted from May 5 to 31, 2020 with 203 respondents. Psychological states were measured with a self-reported numerical scale of fear, the Generalized Anxiety Disorder (GAD-7) scale, and the Patient Health Questionnaire (PHQ-9). The prevalence rates of fear, anxiety, and depression were 60.6, 71.9, and 55.2%, respectively. Compared to non-frontline workers, frontline workers reported higher rates of anxiety (79.0 vs. 67.2%) and depression (65.4 vs. 48.4%). Multivariate logistic regression models showed that working in a public institution, being employed for <5 years, and being over-worked were risk factors for developing psychological distress. Our findings emphasize the need for timely psychological interventions to support the mental well-being of healthcare professionals in Bangladesh.
Social Determinants of Health in Physiatry: Challenges and Opportunities for Clinical Decision Making and Improving Treatment Precision
Authors: Conic Rosalynn R. Z. , Geis Carolyn , Vincent Heather K.
Published: November 2021

Physiatry is a medical specialty focused on improving functional outcomes in patients with a variety of medical conditions that affect the brain, spinal cord, peripheral nerves, muscles, bones, joints, ligaments, and tendons. Social determinants of health (SDH) play a key role in determining therapeutic process and patient functional outcomes. Big data and precision medicine have been used in other fields and to some extent in physiatry to predict patient outcomes, however many challenges remain. The interplay between SDH and physiatry outcomes is highly variable depending on different phases of care, and more favorable patient profiles in acute care may be less favorable in the outpatient setting. Furthermore, SDH influence which treatments or interventional procedures are accessible to the patient and thus determine outcomes. This opinion paper describes utility of existing datasets in combination with novel data such as movement, gait patterning and patient perceived outcomes could be analyzed with artificial intelligence methods to determine the best treatment plan for individual patients in order to achieve maximal functional capacity.
Socioeconomic Determinants of Melanoma-Related Health Literacy and Attitudes Among College Students in China: A Population-Based Cross-Sectional Study
Authors: Wu Tianhao , Wang Xianggui , Zhao Shuang , Xiao Yi , Shen Minxue , Han Xi , Chen Xiang , Su Juan
Published: November 2021

Objectives: To investigate the association of gender, ethnicity, living region, and socioeconomic status (SES) with health literacy and attitudes toward nevi and melanoma in Chinese adolescents and to examine whether health literacy mediates the association of SES with attitudes.

Study Design: A multicenter cross-sectional study was conducted among newly enrolled college students. First-year students were recruited from five universities in different regions of China in 2018 using the cluster sampling method. The observers were blinded to the participants.

Methods: Health literacy and attitudes were measured using a previously validated tool (Nevus and Melanoma Health Literacy and attitudes Test). SES was measured by annual family income and parental highest educational level. Nonparametric test was used to examine the association of participants' characteristics with health literacy and attitudes. Two-level generalized linear model with logarithm link function and Gamma distribution was used individually for SES. The mediation effect model was used to examine the mediation effect of health literacy.

Results: A total of 21,086 questionnaires were completed by college students with a mean age of 18.0 ± 0.8 years. The mean scores of health literacy and attitudes were 9.83 ± 7.46 (maximum score: 28) and 16.98 ± 2.92 (maximum score: 20), respectively. Female, Han nationality, annual family income, and parental educational levels were positively associated with health literacy and attitudes. Regional differences showed different effects on health literacy and attitudes. A mediation model showed that literacy mediated the association of SES with attitudes toward nevi and melanoma. Health literacy mediated ~30–50% of the association of SES with attitudes.

Conclusions: Melanoma-related health literacy among Chinese college students is generally insufficient and needs to be improved. Targeted and personalized health education for improving health literacy related to nevi and melanoma may improve the general population's attitudes and further promote health-related behavior to prevent and identify early-stage melanoma.
Development of the COVID-19 Real-Time Information System for Preparedness and Epidemic Response (CRISPER), Australia
Authors: Field Emma , Dyda Amalie , Hewett Michael , Weng Haotian , Shi Jingjing , Curtis Stephanie , Law Charlee , McHugh Lisa , Sheel Meru , Moore Jess , Furuya-Kanamori Luis , Pillai Priyanka , Konings Paul , Purcell Michael , Stocks Nigel , Williams Graham , Lau Colleen L.
Published: November 2021

Accurate and current information has been highlighted across the globe as a critical requirement for the COVID-19 pandemic response. To address this need, many interactive dashboards providing a range of different information about COVID-19 have been developed. A similar tool in Australia containing current information about COVID-19 could assist general practitioners and public health responders in their pandemic response efforts. The COVID-19 Real-time Information System for Preparedness and Epidemic Response (CRISPER) has been developed to provide accurate and spatially explicit real-time information for COVID-19 cases, deaths, testing and contact tracing locations in Australia. Developed based on feedback from key users and stakeholders, the system comprises three main components: (1) a data engine; (2) data visualization and interactive mapping tools; and (3) an automated alert system. This system provides integrated data from multiple sources in one platform which optimizes information sharing with public health responders, primary health care practitioners and the general public.
Forage-Fed Insects as Food and Feed Source: Opportunities and Constraints of Edible Insects in the Tropics
Authors: Espitia Buitrago Paula Andrea , Hernández Luis Miguel , Burkart Stefan , Palmer Neil , Cardoso Arango Juan Andrés
Published: November 2021

Farmed insects can provide an alternative protein source for humans, livestock, and fish, while supporting adaptation to climate change, generating income for smallholder farmers, and reducing the negative impacts of conventional food production, especially in the tropics. However, the quantity, nutritional quality and safety of insects greatly relies on their feed intake. Tropical forages (grasses and legumes) can provide a valuable and yet untapped source of feed for several farmed insect species. In this perspective paper, we provide a viewpoint of how tropical forages can support edible insect production. We also highlight the potential of tropical forage-based diets over those using organic agricultural or urban by-product substrates, due to their versatility, low cost, and lower risk of microbial and chemical hazards. The main bottlenecks relate to dependence on the small number of farmed insect species, and in public policy and market frameworks regarding the use of edible insects as food, feed and in industrial processes. This perspective will serve interested stakeholders in identifying urgent issues at the research, ethical, marketing and policy levels that can prevent the emergence of new, insect-based value chains and business models, and the nutritional, economic and environmental benefits they promise.
Fast-Track in Minimally Invasive Gynecology: A Randomized Trial Comparing Costs and Clinical Outcomes
Authors: Lambat Emery Shahzia , Brossard Philippe , Petignat Patrick , Boulvain Michel , Pluchino Nicola , Dällenbach Patrick , Wenger Jean-Marie , Savoldelli Georges L. , Rehberg-Klug Benno , Dubuisson Jean
Published: November 2021

Study Objective: Evaluate the effects of a fast-track (FT) protocol on costs and post-operative recovery.

Methods: One hundred and seventy women undergoing total laparoscopic hysterectomy for a benign indication were randomized in a FT protocol or a usual care protocol. A FT protocol included the combination of minimally invasive surgery, analgesia optimization, early oral refeeding and rapid mobilization of patients was compared to a usual care protocol. Primary outcome was costs. Secondary outcomes were length of stay, post-operative morbidity and patient satisfaction.

Main Results: The mean total cost in the FT group was 13,070 ± 4,321 Euros (EUR) per patient, and that in the usual care group was 3.5% higher at 13,527 ± 3,925 EUR (p = 0.49). The FT group had lower inpatient surgical costs but higher total ambulatory costs during the first post-operative month. The mean hospital stay in the FT group was 52.7 ± 26.8 h, and that in the usual care group was 20% higher at 65.8 ± 33.7 h (p = 0.006). Morbidity during the first post-operative month was not significantly different between the two groups. On their day of discharge, the proportion of patients satisfied with pain management was similar in both groups [83% in FT and 78% in the usual care group (p = 0.57)]. Satisfaction with medical follow-up 1 month after surgery was also similar [91% in FT and 88% in the usual care group (p = 0.69)].

Conclusion: Implementation of a FT protocol in laparoscopic hysterectomy for benign indications has minimal non-significant effects on costs but significantly reduces hospital stay without increasing post-operative morbidity nor decreasing patient satisfaction.

Clinical Trial Registration:www.ClinicalTrials.gov, identifier: NCT04839263.
In ovo Feeding as a Tool for Improving Performance and Gut Health of Poultry: A Review
Authors: Das Razib , Mishra Pravin , Jha Rajesh
Published: November 2021

Early growth and development of the gastrointestinal tract are of critical importance to enhance nutrients' utilization and optimize the growth of poultry. In the current production system, chicks do not have access to feed for about 48–72 h during transportation between hatchery and production farms. This lag time affects early nutrient intake, natural exposure to the microbiome, and the initiation of beneficial stimulation of the immune system of chicks. In ovo feeding can provide early nutrients and additives to embryos, stimulate gut microflora, and mitigate the adverse effects of starvation during pre-and post-hatch periods. Depending on the interests, the compounds are delivered to the embryo either around day 12 or 17 to 18 of incubation and via air sac or amnion. In ovo applications of bioactive compounds like vaccines, nutrients, antibiotics, prebiotics, probiotics, synbiotics, creatine, follistatin, L-carnitine, CpG oligodeoxynucleotide, growth hormone, polyclonal antimyostatin antibody, peptide YY, and insulin-like growth factor-1 have been studied. These compounds affect hatchability, body weight at hatch, physiological functions, immune responses, gut morphology, gut microbiome, production performance, and overall health of birds. However, the route, dose, method, and time of in ovo injection and host factors can cause variation, and thereby inconsistencies in results. Studies using this method have manifested the benefits of injection of different single bioactive compounds. But for excelling in poultry production, researchers should precisely know the proper route and time of injection, optimum dose, and effective combination of different compounds. This review paper will provide an insight into current practices and available findings related to in ovo feeding on performance and health parameters of poultry, along with challenges and future perspectives of this technique.
Association of High-Speed Rail and Tuberculosis Transmission in Newly Integrated Regions: Quasi-Experimental Evidence from China
Authors: Liu Yahong , Tang Chengxiang , Bu Tao , Tang Daisheng
Published: November 2021

Objectives: The spread of tuberculosis (TB) is related to changes in the social network among the population and people’s social interactions. High-speed railway (HSR) fundamentally changed the integrated market across cities in China. This paper aims to examine the impact of HSR on TB transmission in newly integrated areas.

Methods: By exploiting the opening and operation of the first HSR in Sichuan province as a quasi-natural experiment, we have collected and used the economic, social, and demographic data of 183 counties in Sichuan province from 2013 to 2016.

Results: The new HSR line is associated with a 4.790 increase in newly diagnosed smear-positive TB cases per 100,000 people among newly integrated areas. On average, an additional increase of 34.178 newly diagnosed smear-positive TB cases occur every year in counties (or districts) covered by the new HSR.

Conclusion: HSR development has significantly contributed to the transmission of TB. The public health system in China needs to pay more attention to the influences of new, mass public transportation.
The state of the antioxidant defense of the body of ice hockey players during the sports season
Authors: Rakhmanov Rofail Salykhovich , Bogomolova Elena Sergeevna , Razgulin Sergey Aleksandrovich , Khayrov Rashid Shamilevich
Published: November 2021

Excessive formation of free radicals and active forms of nitrogen damages enzymes, proteins, membrane phospholipids, nucleic acids. The indicators of the antioxidant defense of the body of professional ice hockey players were evaluated under oxidative and nitrosive stresses of various degrees during the game season. In blood samples of hockey players (n = 39), taken after 2.5 months, 4 and 6 months. games were determined by glutathione (total, reduced, oxidized), nitric oxide. Oxidative stress was ranked according to the levels of peroxides, the state of the antioxidant system — according to decomposed exogenous peroxide. Cortisol and testosterone were evaluated. Total glutathione exceeded the reference standards. Reduced and oxidized glutathione (below 10 units) indicated a decrease in antioxidant protection within 4 months. Nitric oxide increased to 71.6–103.2 μM / L; nitrosive stress was detected in 38.5 %. Testosterone was within normal limits, cortisol was higher in 80.0–95.8 %. Average oxidative stress was detected in 20.7 %, high — in 4.0 %; the antioxidant capacity of the whey is medium to high. Total and reduced glutathione, peroxides, and decomposed peroxide confirmed the significant compensatory reserves of the body. The metabolism was dominated by catabolic processes. The periods of maximum growth of the level of cortisol (2.5–4 months of games) corresponded to the minimum levels of the body’s antioxidant defense; individuals with signs of nitrosive stress were registered. This has proven to be a health risk of exercise in athletes. The condition for the prevention of dysadaptation shifts is the optimal level of stress at the stages of the playing season, as well as ensuring the high-quality composition of the diet.

English version of the article is available at URL: https://panor.ru/articles/state-of-antioxidant-protection-of-ice-hockey-players-during-the-sports-season/72915.html
The hygienic significance of the heating microclimate in the formation of health disorders of workers (review)
Authors: Novikova Tamara Anatolyevna , Abramkina Svetlana Sergeevna , Aleshina Yuliya Aleksandrovna
Published: November 2021

The thermal effect of the working environment, leading to overheating of the body of workers, can manifest itself as thermal injuries, accompanied by a deterioration in well-being, a decrease in working capacity, and various health disorders. In addition, an increased air temperature can become a trigger for the activation of biological effects caused by other industrial factors— noise, vibration, harmful chemicals, physical exertion, the combined effect of which has a potentiating effect. The aim of the work was to analyze the literature data on the study of the negative impact of the heating microclimate on the health of workers and to determine measures for its prevention. The analysis of domestic and foreign sources of scientific information and publications contained in Russian and international search systems (databases eLIBRARY, PubMed, etc.) devoted to the study of the features of the formation of a heating environment and its influence on the formation of health disorders of workers in various industries and agriculture. The importance of studies of the heating microclimate as a factor of occupational health risk is shown, the directions of primary prevention of its negative impact, aimed at protecting against overheating and normalizing the thermal state of the workers’ body, are determined. Analysis of literature data allowed us to conclude that the negative health effects of the thermal effects of the working environment are currently insufficiently studied, further research is needed to assess occupational risks associated with its exposure, as well as the processes of adaptation to the thermal load of workers in various industries and agriculture, taking into account their specifics.
History of hygiene, microbiology and epidemiology in the art of small forms: the past and the present
Authors: Tolmachev Roman Aleksandrovich , Podunova Lyudmila Grigorievna , Glyantsev Sergey Pavlovich
Published: November 2021

For the first time, more than 700 award, anniversary and commemorative badges reflecting the history of hygiene, microbiology and epidemiology were systematized and analyzed. The following directions are identified for studying the history of these medical specialties and educational and scientific disciplines with the help of epigraphy: 1) outstanding figures of hygiene, microbiology and epidemiology; 2) hygienic and epidemiological congresses, congresses and other forums; 3) specialized research institutions; 4) educational institutions and faculties of universities that train specialists in the field of hygiene, microbiology and epidemiology; 5) pathogens and vectors of infectious diseases; 6) methods of detecting microorganisms and treating infections; 7) the COVID-19 pandemic. The study showed that during the XX and XXI centuries a large number of badges (awards and commemorative) were issued, reflecting selected pages of the history of hygiene, microbiology and epidemiology. These faleristic objects related to the art of small forms are full-fledged primary sources for studying the history of these areas of medicine and objects for the collections of state, municipal and departmental museums of medical subjects. Signs with portraits of outstanding hygienists, microbiologists and epidemiologists can be used to study and illustrate their life and activities, contribution to science and perpetuate their memory. Epigraphy on the presented signs can help both in establishing the time of a particular fact or event in the past (for example, the dates of the life and activity of an outstanding scientist; the time, place and subject of the scientific forum, the opening date of the research institute, educational institution, faculty or department, etc.), and the specifics of conducting scientific research in the field of hygiene, microbiology and epidemiology (pathogens and vectors of diseases; concepts, devices and research methods, methods of diagnosis and prevention of infectious diseases, etc.).
Leases that are not leases: qualification and accounting
Authors: Sotnikova L.V.
Published: November 2021

On the eve of the entry into force for the mandatory application of all enterprises and organizations of the Russian Federation of the Federal Accounting Standard 25/2018 “Lease Accounting”, approved. By order of the Ministry of Finance of Russia dated October 16, 2018 No. 208n, from January 1, 2022, many heads of economic structures, including healthcare organizations, and their accountants, who act as tenants in lease agreements, are concerned about avoiding the complicated accounting of leased objects which is prescribed by this standard. Accounting methodologists, consultants, experts, and others try to use literally every clause, subclause, paragraph, every word and every comma in order to justify that their lease relationship is not covered by this accounting standard.
Consideration of breakthrough technologies in the field of genomic research and artificial intelligence in healthcare
Authors: Chkhutiashvili L.V.
Published: November 2021

The article is devoted to the analysis of technologies in the field of genomic research and artificial intelligence and their reflection in the accounting of healthcare institutions. Less than a quarter of the 21st century has passed, and during this time humanity has made a huge number of technological breakthroughs, both in the field of genomic research and in the field of artificial intelligence. Artificial organs and prosthetics that allow a person to live longer and more comfortably; the creation of mobile Internet, social networks and messengers that have accelerated and simplified the transfer of information between people; electric cars that are eco-friendly, maneuverable and do not require fossil resources, which sooner or later may end; self-driving cars that free up time that a person can devote to important things than driving a car; virtual and augmented reality, in which a person can safely and with pleasure move for a certain time, have become our everyday reality. The level of development of healthcare and education, the rationality of public administration and business efficiency, the speed of making space breakthroughs in other areas of human life depend on genomic research and achievements in the field of artificial intelligence.
Peculiarities of application of zero corporate tax rate by medical companies
Authors: Shinkareva O.V.
Published: November 2021

In this article, the peculiarities of applying the zero income tax rate of organizations by medical companies are considered. The requirements that, according to the Tax Code of the Russian Federation, must be fulfilled by medical organizations to impose the profit received at a rate of 0% are considered: the types of activities for which profit is subject at this rate, the presence of a certain percentage of medical personnel, restrictions on the number of employees and other restrictions. Listed are the types of reporting that should be additionally submitted by a medical organization that has expressed a desire to apply a zero rate, as well as the consequences of not submitting these documents. Features of voluntary transition to profit levying at a rate of 20% are shown, practical examples are given.
YIELD AND QUALITY OF WINTER WHEAT GRAIN UNDER NON-MOLDBOARD SOIL TILLAGE DEPENDING ON DOSES OF MINERAL FERTILIZERSIN THE CROP ROTATIONS OF THE CENTRAL CHERNOZEM REGION
Authors:   Federal Agricultural Kursk Research Center, Lukyanov V.A. , Nitchenko L.B. ,   Federal Agricultural Kursk Research Center
Published: November 2021

In modern agriculture, resource-saving technologies for cultivating grain crops and their optimization are becoming more and more relevant. The use of scientifically-based crop rotations, tillage methods and doses of mineral fertilizers allow increasing economic efficiency of winter wheat cultivation. The purpose of the research was to assess the yield and quality of winter wheat grain depending on different doses of mineral fertilizers under non-moldboard soil tillage in the crop rotations of the Central Chernozem Region. The research was carried out in 2012-2020 in a stationary multifactorial field experiment in Federal Agricultural Kursk Research Center. The experimental design included the following options: Factor A – crop rotations (grain-fallow-row, grain-grass-row, grain-grass); Factor B – mineral fertilizers (without fertilizers, N20P40K40, N40P80K80 kg ha-1). The soil of the experimental site is represented by typical, medium-loamy chernozem. The paper shows that the yield of winter wheat grain in the context of non-moldboard soil tillage was higher in the grain-fallow-row crop rotation and amounted to 3.34 t ha-1. In the grain-grass-row and grain-grass crop rotations, yield decreased by 6.6 % and 10.2 %, respectively. The maximum grain yield (3.98 t/ha-1) was obtained in grain-fallow-row crop rotation with N40P80K80. An increase in fertilizers doses led to protein and gluten content increment from 12.6 to 13.3 % and from 22.8 to 25.6 %, respectively; however, the differences in crop rotations were within the limits of experimental error. The grain nature varied according to the studied factors from 708 to 735 g/l-1 and was higher in the grain-fallow-row crop rotation with a dose of mineral fertilizers N40P80K80. Despite more significant net income after increased fertilizers dose (N40P80K80), the increase in the winter wheat grain yield did not allow obtaining a higher level of profitability compared to N20P40K40. Winter wheat cultivation in grain-grass-row crop rotation with N20P40K40 was the most cost-effective. In this variant, the cost of grain was the lowest (4.92 thousand rubles t-1); the profitability, on the contrary, was the highest (103.4 %).
ANALYSIS OF PROMISING STRAWBERRY HYBRID FORMS BY FAOMT AND FAFAD1 FRUIT AROMA GENES
Authors:   I.V. Michurin Federal Scientific Center, Lyzhin A.S. , Luk'yanchuk I.V. ,   I.V. Michurin Federal Scientific Center
Published: November 2021

An important consumer trait of strawberry fruits is their aroma. Among the most important strawberry fruit aroma compounds are γ-decalactone and mesifurane. The content of γ-decalactone in fruits is controlled by the expression of the FaFAD1 gene. The content of mesifurane in fruits is controlled by the FaOMT gene. Identification of genotypes carrying the target alleles of the aromatic complex genes is an important stage in improving the strawberry assortment and creating strawberry varieties with aromatic fruits. The purpose of the study is molecular genetic analysis of strawberry hybrid seedlings by the FaOMT and FaFAD1 genes to identify genotypes promising in breeding for fruit aroma. Promising selected and elite forms of strawberry (Fragaria × ananassa Duch.) created at the FSSI “I.V. Michurin FSC” were used as biological objects. To identify the allelic state FaOMT gene, the codominant molecular marker FaOMT-SI/NO was used. To identify FaFAD1 gene, the molecular marker FaFAD1 was used. Using the FaOMT-SI/NO marker, the functional allele of the FaOMT gene (FaOMT+) was identified in the following strawberry selected forms: 298-19-9-43 (FB2 F. orientalis Los., F. moschata Duch., F. × ananassa Duch.), 932-29 (F. virginiana subsp. platypetala (Rydb.) Staudt × ‘Feyerverk’), 928-12 (298-19-9-43 × ‘Privlekatelnaya’), 69-29 (‘Feyerverk’× ‘Bylinnaya’), 72-25, 72-71 (‘Privlekatelnaya’ × ‘Bylinnaya’) and 26-5 (‘Rubinovyy kulon’× 298-19-9-43). The FaFAD1 gene was identified in strawberry hybrids 72-25 (‘Privlekatelnaya’ × ‘Bylinnaya’), 56-8 (‘Gigantella’ × ‘Privlekatelnaya’) and 61-12 (‘Bylinnaya’ × ‘Olimpiyskaya nadezhda’). The strawberry selected form 72-25 (‘Privlekatelnaya’ × ‘Bylinnaya’) is characterized by a combination of functional alleles of both genes (FaOMT + FaFAD1). Involvement of these forms in hybridization will make it possible to intensify the process of creating new strawberry varieties with improved fruit aroma.
SOURCES OF HIGH-QUALITY GRAIN IN WINTER COMMON WHEAT BREEDING
Authors:   North Caucasus Federal Agricultural Research Centre, Sokolenko N.I. , Galushko N.A. ,   North Caucasus Federal Agricultural Research Centre, Komarov N.M. ,   North Caucasus Federal Agricultural Research Centre
Published: November 2021

Research on improving winter common wheat varieties in the context of combining high yield and grain quality is relevant. The research aimed to evaluate and select variety samples of winter common wheat with high technological indicators of grain quality for breeding purposes. In this study, we analyzed grain from 10 variety samples of the world collection; winter wheat grain of variety ‘Aivina’ served as a standard. Soil – ordinary medium-loamy medium-thick low-humus chernozem. Wheat was grown on the experimental fields of the North Caucasus FARC in the zone with unstable moistening on bare fallow. Grain vitreousness percentage in 2019 ranged between 44.0 and 53.0 %, in 2020 – 30.5–50.0 %. In the same years, this indicator for variety-standard ‘Aivina’ was 56.0 and 48.0 %, respectively. The gluten content in the grain depended on the weather conditions and genotype. Grain of all varieties harvested in 2019, including standard ‘Aivina’, had a high gluten content (28.2–35.6 %) and corresponded to strong wheat. In 2020, the situation was absolutely different. The amount of gluten in the grain of variety samples harvested in 2020 ranged between 22.9 and 34.6 %; for ‘Aivina’, this indicator reached 26.9 %. The gluten quality in all variety samples during the years of research was typical for class 2. The variety samples were characterized by a high protein content in the grain – 16.7–20.8 % and 13.5–20.4 %; the same indicator for ‘Aivina’ was 16.7 and 15.8 %. Sedimentation rate in the variety samples was 50–81 ml and 34–64 ml; in ‘Aivina’ – 50 and 43 ml. Maximum sedimentation values were noted for the variety ‘Prestizh’. It indicates the ability to form grain, the strength of which is typical for wheat-improver. The correlation between sedimentation and gluten content (r = 0.63), as well as between sedimentation and the falling number (r = 0.73), was positive and significant during the years of research. All studied genotypes are promising for breeding new wheat varieties as sources for obtaining high-quality grain.
ASSESSMENT OF ECOLOGICAL PLASTICITY AND STABILITY OF SPRING BARLEY
Authors:   SSE “Agricultural research center «Donskoy»”, Filippov E.G. , Bragin R.N. ,   SSE “Agricultural research center «Donskoy»”, Dontsova A.A. ,   SSE “Agricultural research center «Donskoy»”, Dontsov D.P. ,   SSE “Agricultural research center «Donskoy»”
Published: November 2021

Spring barley breeding in the Rostov region is aimed at developing early maturing, drought-resistant, high-yielding varieties with good technological qualities of grain. Productivity is mainly affected by the economic and biological parameters of the variety and the environmental conditions in the growing area. The purpose of the research is to conduct a comparative assessment of spring barley varieties by indicative parameters of ecological plasticity and yield stability to changes in environmental conditions. In 2018-2020, for a targeted study of this impact, trials with 18 spring barley varieties of Russian and foreign breeding to estimate their ecological adaptability and stability were carried out. Square of the plot – 10 m2; experiment was replicated thrice. Soil – chernozem ordinary with humus content in the arable layer at the level of 3.0–3.5%, pH = 7.0–7.1. Phosphorus content – 15–20 mg/kg of soil, exchangeable potassium – 300–500 mg/kg. The estimation of the effect on the ecological plasticity and stability of varieties was carried out according to the method of S.A. Eberhart, W.A. Rassel edited by V.A. Zykin (2005). Indicators of homeostaticity and breeding value were calculated according to the V.V. Khangildin and N.A. Litvinenko method (1981). Over the years of research, the productivity formation was mainly influenced by the factors ‘variety’ (66.1%) and ‘year’ (31.7%). The environmental conditions index showed that more favorable growing conditions were in 2020 (Ij = +0.23); in 2018, on the contrary, they were relatively unfavorable (Ij = –0.19). As a result of the three-year analysis, the highest productivity was identified in the varieties ‘Format’ (4,9 t/ha), ‘Fedos’ (4,8 t/ha) and ‘Gris’ (4,8 t/ha). In general, according to the complex of adaptivity parameters, ‘Format’ variety was distinguished. It has high indicators of breeding value (Sc = 4.6), stress resistance (Ymin-Ymax = –0.3), high stable productivity, as well as a high homeostatic index (Hom = 531) and a low coefficient of variation (V = 3.1%).
BIOLOGICAL CONTROL OF PHYTOPARASITIC NEMATODES BASED ON MICROORGANISMS (REVIEW)
Authors:   Federal Research Center of Biological Plant Protection, Homyak A.I. , Asaturova A.M. ,   Federal Research Center of Biological Plant Protection, Sidorov N.M. ,   Federal Research Center of Biological Plant Protection, Dubyaga V.M. ,   Federal Research Center of Biological Plant Protection
Published: November 2021

Phytoparasitic nematodes are dangerous pests of agricultural crops. Annually, yield losses due to damage by phytonematodes are up to 15%, which is estimated at billions of dollars. The aim of the research is to summarize and analyze scientific publications concerning the harmfulness of phytoparasitic nematodes and microorganisms that have an antagonistic effect against them for the further development of biopreparations of nematicidal action based on antagonist bacteria. The study objectives are to identify the most common groups of nematodes, review the information concerning microorganisms that have a nematicidal effect and biological products based on them. The review considers the main representatives of nematodes – plant parasites and notes their habitat, harmfulness, affected crops and symptoms of infection. Brief descriptions of life cycles and systematic affiliation are given. Analysis of scientific publications on the studied topic shows that numerous microorganisms are capable of exhibiting nematicidal activity, directly or indirectly affecting nematodes in the soil. In the course of the analysis of literary sources, it was found that both fungi and bacteria can exhibit an antagonistic effect against phytoparasitic nematodes. It is noted that for both groups of microorganisms, there are several mechanisms of action: predation, parasitism, competition, etc. It has been found that fungi and bacteria synthesize metabolites of various natures with a nematicidal effect: toxins, lytic enzymes, antibiotics, siderophores. It should be noted that microorganisms-antagonist are capable of exhibiting nematicidal activity to nematodes of different stages of the life cycle: eggs, juveniles and adults. Nowadays, some commercial preparations based on antagonist microorganisms are successfully used in agriculture in different countries. During the analysis, it was discovered that to date, few viruses are capable of infecting nematodes; their systematic affiliation has also been established. It is noted that, if compared to bionematicides based on fungi and bacteria, not a single bionematicide based on viruses has been developed. The development of bionematicides based on antagonist microorganisms is a promising area but requires further studies of interactions in the plant-nematode-microorganism system.
METHODOLOGICAL APPROACHES TO THE ASSESSMENT OF THE ENTOMOPATHOGENIC ACTIVITY OF MICROORGANISMS AGAINST INSECT PESTS IN VITRO (REVIEW)
Authors:   Federal Research Center of Biological Plant Protection, Bondarchuk E. Yu. , Tsygichko A.A. ,   Federal Research Center of Biological Plant Protection, Asaturova F.M. ,   Federal Research Center of Biological Plant Protection
Published: November 2021

Excessive application of chemical insecticides in agriculture has led to some serious problems that threaten the environment and human health. One of the possible ways to overcome the situation is to shift to environmentally-friendly preparations based on entomopathogenic bioagents. The purpose of this review was to search for and systematize methodological approaches to determine the entomopathogenic activity of microorganisms of various taxonomic groups in laboratory conditions. The expediency of choosing the necessary method when studying a particular phenomenon or process is an important point both in the fundamental and applied field of research. The primary assessment of the entomopathogenic activity of microorganisms in vitro is the basis for expanding the spectrum of their action, introducing new strains into collections. It also contributes to the replenishment of knowledge about the already known properties of various types of microorganisms. All this, certainly, is connected with the further choice of them as biological agents. Each of the presented groups of entomopathogens has its distinctive features of the mechanisms of action determined by the target insect. Concerning the choice of methodological approaches for assessing the entomopathogenic effect of fungi, the authors relied on the physiological characteristics of the insect and its stage of harmfulness. The researchers were guided by methodological approaches of oral infection of insects using an infected food source to study the activity of bacterial strains. Pathological changes in the cellular structure, as well as deformations of intestinal elements, were noted. The most common way to assess the effect of entomopathogenic viruses in the laboratory is the method of surface infection of the food source of the tested insect, taking into account the high specialization of the agent. When studying the mechanisms of action of fungal, bacterial and viral agents, researchers injected a suspension of the pathogen into the insect’s body. The search and systematization of relevant methodological approaches to assess entomopathogenic microorganisms depending on the taxonomic affiliation is an important part of the work directly related to the development of a high-quality and effective bioinsecticide.
BALANCE OF NUTRITION ELEMENTS IN CROP ROTATION UNDER BIOLOGIZED ADAPTIVE LANDSCAPE FARMING
Authors:   Federal Agricultural Research Center of the North-East named N.V. Rudnitsky, Kozlova L.M. , Noskova E.N. ,   Federal Agricultural Research Center of the North-East named N.V. Rudnitsky, Popov F.A. ,   Federal Agricultural Research Center of the North-East named N.V. Rudnitsky, Svetlakova E.V. ,   Federal Agricultural Research Center of the North-East named N.V. Rudnitsky
Published: November 2021

In the light of recent developments, the use of biological techniques in crop cultivation technologies needs to be expanded. The role of crop rotations with a high proportion of legume grasses, green manure crops and intermediate crops is increasing. The purpose of the research is to study soil fertility dynamics in terms of the main nutritional elements and determine their balance for the development of the adaptive landscape farming system in the North-Eastern region of the European part of Russia. Experiments were carried out on the experimental plots of the FARC of the North-East in 2002–2009. Soil – sod-podzolic middle loamy. We analyzed data of a long-term stationary experiment in four grain-fallow-grass field crop rotations. Meteorological conditions during the years of research were close to the average long-term values and favorable for crop cultivation. The introduction of low doses of fertilizers (N45P45K45 as mineral, 11.5–22.5 t/ha as green manure) increased the content of mobile phosphorus in the soil by 11–14 mg/kg (LSD05 = 9.5) in crop rotations with occupied and green manure fallows. An increase in exchangeable potassium by 15 mg/kg (LSD05 = 14.1) was noted in crop rotation with two clover fields for green manure. A positive balance of nitrogen and phosphorus was obtained in crop rotation with occupied and green manure fallows. The nitrogen balance was with a higher intake of +157.8 – +483.5 kg/ha and balance intensity – 115–140 %. The balance of phosphorus has developed at +6.0…+49.6 kg/ha. The positive balance of potassium was only in crop rotations with the introduction of green manure fertilizers and intermediate crop (+69.9…+175.8 kg/ha). The intensity of the balance of these elements was 101–118 %. In the control crop rotation with bare fallow at a minimum intake of nutrients, the negative balance of nitrogen, phosphorus and potassium was obtained; the intensity was below 100 %. Productivity of crop rotation was at the level of 4.90–5.41 thousand fodder units. According to the optimal combination of productivity and the balance of nutritional elements, crop rotation with two clover fields for green manure and an intermediate crop stood out.
DROUGHT TOLERANCE OF THE NEW SELF-POLLINATED LINES OF MAIZE AND THE METHODS OF ITS ESTIMATION
Authors:   SSE “Agricultural research center «Donskoy»”, Krivosheev G.Ya. , Shevchenko N.A. ,   SSE “Agricultural research center «Donskoy»”, Ignatiev A.S. ,   SSE “Agricultural research center «Donskoy»”
Published: November 2021

More than half of the maize crops in the Russian Federation are located in areas with insufficient and unstable moisture. With this in mind, Z. mays breeding for drought tolerance is extremely important. The purpose of the current study is: investigate the drought tolerance of self-pollinated maize lines by various methods, identify the best samples for further breeding, establish indirect criteria for estimating drought tolerance. The study was conducted at the Agricultural Research Center “Donskoy” located in the southern part of the Rostov region, which is characterized by unstable moisture. The years of the study turned out to be dry (Selyaninov Hydrothermal Coefficient (HTC) = 0.32–0.89). The new self-pollinated lines of maize were used as initial material and studied for resistance to water stress (41 pcs. in 2011–2013, 39 pcs. in 2015–2017, 25 pcs. in 2018–2020). According to the guidelines for maize breeding, the following indicators of productivity were taken into account: number of ears per plant, weight of one ear, 1000-grain weight, number of grains per ear, etc. In 2011–2013, based on the comprehensive estimation, new middle-early drought-tolerant self-pollinated lines of maize ‘DK47111’, ‘SP203’, ‘KS211’, ‘S204’ and ‘S238’ were identified. They were characterized by the low values of residual water deficit both in the flowering (6.9 – 12.8%) and milk-wax (9.0 – 13.4%) stage, high drought tolerance index (68.6 – 85.6%), deep root system (force of uprooting the plants from the ground was 54.0–67.7 kgf), minimum gap in the flowering of male and female inflorescences (1–2 days). In 2015–2017, according to the method of residual water deficit (RWD), the following lines were identified ‘KV334’, ‘RD6’, ‘DS498/217-4’, ‘DS257/85-3’, ‘DS257/85-1’, ‘DS257/85-6’, ‘DS257/85-4’. In 2018–2020, the new self-pollinated lines of maize ‘KS317A’, ‘KV240’, ‘LSh16’, ‘S86’, ‘LSh17’ and ‘LSh2’ showed high resistance to water stress. We recommend the following selection criteria when creating new lines: absence of infertility and kernel percentage of the ears.
Acromegaly: Approaches to the Optimization of Medical Treatments
Authors:   Moscow Regional Research and Clinical Institute, Ilovayskaya I.A.
Published: November 2021

Acromegaly is a chronic disease that often requires long-term medical treatment. The main group of drugs for acromegaly consists of the first-generation somatostatin analogues such as octreotide and lanreotide. It is also possible to use the dopamine receptor agonist cabergoline. Since 2018, one more growth hormone antagonist, pegvisomant, has been registered in Russia. The goal of drug therapy is to normalize the level of insulin-like growth factor 1, so it is fundamentally important to monitor this indicator. If the level of insulin-like growth factor 1 does not normalize during the use of octreotide or lanreotide in maximum doses for 3–12 months, it is necessary to optimize therapy. In the case of complete resistance to somatostatin analogues, it is possible to switch to pegvisomant, as well as active neurosurgical and/or radio surgical intervention. In case of partial resistance, the use of combination therapy with somatostatin analogues and cabergoline/pegvisomant is justified. The article discusses and justifies various options for optimizing the drug treatment of acromegaly.
proyectos de vinculación una estrategia de mejora en la gestión contable del sector microempresarial
Authors: Carchi Arias Kenia Lizzeth , Juca Maldonado Fernando Xavier , Romero Lalangui Martín Andrés , Orellana Arévalo Betzy Lizbeth
Published: November 2021

El presente artículo tuvo como objetivo describir el nivel de desarrollo de potencialidades en la gestión contable y tributaria de los microempresarios como resultado de las capacitaciones en línea, las mismas que fueron disertadas por estudiantes involucrados en elproyecto de vinculación de la carrera de Contabilidad y Auditoría de la Universidad Metropolitana.  Desde  la  integración de la profesionalización alumno- docente se fortalece la investigación, y el compromiso social frente a los actores externos. La metodología fue descriptiva- longitudinal, porque muestra el nivel de mejora en el aprendizaje adquirido por los participantes; concluyendo que el 81% de los aprobados alcanzaron un nivel de recuperación del 23%, en relación  con el promedio inicial. Así como también  la valoración del test post hoc expone que  el  mayor  rendimiento   obtenido de los seis cursos; tributación básica y Excel intermedio tiene promedios que están en un rango de 90 a 100 puntos, considerándolos de mayor puntuación.