bluuebunny/crossref_metadata_2025 huggingface dataset:
Use of a Composite Survival Curve to Optimise the Surgical Strategy for Double Inlet Left Ventricle
Authors: Mark Awori N , Jonathan Awori A , Hassan Ibrahim M , Kimberly Kipkoech
Published: October 2022

Objectives: Palliative surgery has improved the long-term survival of patients with Double inlet left ventricle (DILV). Neonates and infants with DILV presenting with reduced pulmonary blood flow (RPBF) are often offered a systemic arterial-to- pulmonary artery shunt (SAPAS). There is evidence that SAPAS in these patients, may not improve survival compared to the natural history. An objective assessment of the efficacy of a treatment requires a comparison of the treatment outcome with the natural history. Our aim was to review the literature to determine whether SAPASs in patients with DILV and RPBF improves survival compare to the natural history. Methods: We reviewed the literature and used the most externally valid data to create a composite survival curve that facilitates the comparison of surgical outcome and natural history. Results: The data suggests that SAPASs in patient with DILV and RBPF, may not improve long term survival compared to the natural history. There is also evidence that palliative surgery in general in patients older than 1 year of age with increased or balanced pulmonary blood flow may not improve survival compared to the natural history. Conclusions: SAPASs probably should not be offered to patients with DILV and RPBF. In addition, cardiac surgery probably should not be offered to patients with DILV presenting for the first time after 1 year of age.
SARS-CoV-2 Neutralizing Antibody Presence in Infected and Vaccinated Patients
Authors: Emily Denis St, , J Jackson , R Turner , J Farajzadeh , K Yukutake , Y Valles-Ayoub , S Beqaj , M Pietruszka
Published: October 2022

Purpose: To understand persisting knowledge gaps among providers in Maryland regarding HIV prevention for minors and evaluate the providers’ comfort and likelihood of prescribing oral pre-exposure prophylaxis (PrEP), and their perceived barriers and facilitating factors to prescribing PrEP. Methods: Between January 2021 and June 2021, we conducted semistructured, audio-recorded interviews of 18 community health clinicians who provide care to adolescents in Maryland. This qualitative study was well suited as a case study. The theories that served as the primary orienting lens for this research were the theory of planned behavior, and the diffusion of innovation. Results: A total of 18 providers participated in the study. Nine main themes emerged. While reasonable knowledge was noted among most participants regarding the concepts of PrEP, only half (50%) were knowledgeable about the Maryland Minor Consent Law (MMCL) for HIV prevention treatment. In addition, the providers had dissimilar experiences in the prescription of PrEP. Conclusion: Most of the participants were knowledgeable about PrEP, and many were also experienced in prescribing PrEP to eligible adults. Several provider-level barriers to prescribing PrEP were reported. Consequently, the implementation of PrEP in HIV clinics may be challenging without failing to address HIV providers’ concerns.
O vivido do parto vaginal pela fenomenologia heideggeriana: contribuições para a enfermagem obstétrica
Authors: Elias Elayne Arantes , Floriani Dayanne Teresinha Granetto Cardoso , Manhães Letycia Sardinha Peixoto , Paiva Andyara do Carmo Pinto Coelho , Silva Lauanna Malafaia da , Zechini Anderson Freitas de Menezes , Torres Daniele  Maria Alves , Souza Juliana Gaia de , Souza Wallace Silva de , Soares Glaucimara Riguete de Souza
Published: October 2022

Objetivos: descrever os significados, sentidos e sentimentos das mulheres no parto normal e no puerpério e compreender o papel do enfermeiro nesse processo. Metodologia: pesquisa fenomenológica heideggeriana com 14 mulheres que passaram pelo parto vaginal. Foram realizadas entrevistas abertas gravadas e constituídas as unidades de significação, a compreensão vaga e mediana e a hermenêutica. Resultados: o vivido do parto significou: sentir bastante dor, ser demorado e não ter forças, e ter tido um pós-parto difícil com o filho e com o seu corpo; ter tido medo do parto, ter sido sofrido traumatizante e assustador; e ter passado por intervenções, ter tomado medicação, não ter tido um bom tratamento e nem orientação. A atuação do enfermeiro não foi definida e os relatos de situações desagradáveis não possibilitaram identificar um profissional específico. Conclusão do estudo: o vivido revelou violência obstétrica e temor, que podem ser evitados com condutas éticas, amparo legal, assistência qualificada e com o conhecimento dos direitos, pelas mulheres e pelos profissionais que cuidam, sobretudo os enfermeiros. A atuação da enfermagem obstétrica abrange a assistência qualificada e humanizada desde o pré-natal ao puerpério e deve ser expandida nas instituições de saúde materno-infantil.
A modulação intestinal como fator relevante no enfrentamento do quadro de depressão
Authors: Primavera Yanataysha de Souza Lima , Bezerra Taís Freitas , Souza Ruane Ramos de , Freitas Francisca Marta Nascimento de Oliveira , Ferreira José Carlos de Sales
Published: October 2022

O presente trabalho busca descrever os aspectos que asseveram o quadro de disbiose intestinal e, consequentemente, o acometimento de depressão e como a modulação intestinal pode colaborar com a melhoria da qualidade de vida de pacientes. A possibilidade de aprofundamento desse estudo colabora com pesquisas que visam reduzir os impactos do desequilíbrio da microbiota na relação do eixo intestino-cérebro. A metodologia consta consiste em uma revisão sistemática de coletas de dados, a partir de pesquisa bibliográfica, na produção publicada em bases da LILACS, PubMed e Google Acadêmico. Estudos apontam que o uso de probióticos e simbióticos de forma prolongada pode afetar positivamente o humor, o fenótipo relacionado à ansiedade e depressão, modular o eixo hipotálamo-pituitária-adrenal, alterar a atividade cerebral e aumentar o neurotransmissor inibitório GABA, reduzindo assim sintomas de ansiedade e depressão. Entretanto, ressalta-se a necessidade de novos estudos para maior controle das variáveis (alimentação, exercícios, grau da depressão). Desta forma, esse recorte científico ressalta um caminho para que a sociedade enfrente os distúrbios relacionados entre cérebro e intestino, destacando-se que estratégias modulatórias podem auxiliar, consideravelmente, na melhora da qualidade de vida dos pacientes afetados pela depressão.
O desafio do manejo clínico da doença de Cushing: relato de caso
Authors: Melo Isabela Moreira , Dias Amanda Furtado , Aguiar Laila Andressa de , Fidelis Beatriz Carraro Arantes , Nunes Marilene Rivany , Maciel Tatiana
Published: October 2022

Doença de Cushing é causada pelo adenoma de hipófise corticotrófico que aumenta o nível de cortisol e consequentemente os níveis de glicose no sangue e o depósito de gordura nos tecidos e órgãos. Esse estudo propõe relatar o caso de uma paciente portadora dessa patologia rara visando entender a síndrome que o hipercortisolismo/adenoma resulta e discorrer sobre o desafio clínico. Trata-se de um estudo de caso cujos dados foram obtidos por meio de avaliação de prontuário cedido pela paciente, análise dos exames diagnósticos realizados e revisão da literatura. A paciente de 21 anos queixava de obesidade de difícil controle. Foram realizados exame físico, exames laboratoriais e de imagem os quais levaram a hipótese diagnóstica de adenoma de hipófise. Após o procedimento de retirada cirúrgica, o material foi encaminhado ao anatomopatológico para biópsia, que confirmou o diagnóstico de adenoma de hipófise corticotrófico. Há que se atentar para as anormalidades clínicas causadas pelo excesso de cortisol relacionados ao diagnóstico, contemplando a necessidade de um tratamento multidisciplinar.
O impacto da pandemia de COVID-19 na saúde materna de gestantes no Brasil: uma revisão integrativa
Authors: Santos Wályssa Cheiza Fernandes , Silva Carla Lins da , Lapa Vanessa Silva
Published: October 2022

Objetivo: Identificar, através das evidências literárias, o impacto da pandemia de COVID-19 na saúde materna de gestantes no Brasil. Metodologia: Trata-se de uma revisão integrativa realizada nas bases de dados eletrônicas Lilacs, Pubmed e Scielo, por meio dos seguintes descritores: “COVID-19”, “SARS-CoV-2”, “severe acute respiratory syndrome coronavírus” e “pregnancy”. Foram incluídos textos completos, disponíveis em português, inglês ou espanhol, publicados entre janeiro de 2020 a junho de 2022; estudos que abordassem fatores relacionados à desfechos obstétricos de gestantes infectadas por COVID-19 ou características da assistência a essas gestantes durante a pandemia de COVID-19 no Brasil. Resultados: Nove artigos compuseram a amostra final desse estudo. Grande parte das pesquisas utilizaram o estudo de coorte, apresentando nível de evidência moderado (III). Constatou-se elevado risco de partos cesáreos, partos prematuros e maiores taxas de internações em unidades de terapia intensiva entre gestantes com COVID-19, destacando-se o fato de que a pandemia favoreceu no déficit de consultas de pré-natal realizado na rotina nas redes de Atenção Primária à Saúde, provocando baixo acesso ao atendimento de gestantes devido a rápida disseminação do vírus. Conclusão: Verificou-se diversos desfechos maternos desfavoráveis em gestantes infectadas por COVID-19 no Brasil, desde os principais fatores associados a maior gravidade da doença, bem como aqueles associados a um maior risco de óbito, demandando uma assistência mais especializada pelas equipes de saúde, além de estudos mais robustos com enfoque no Brasil.
Estudo dos Agronegócios 4.0 – Tecnologias, desafios e benefícios nos Agronegócios
Authors: Oliveira Vinicyo Luan Chagas de , Marinho Max Robert , Oliveira Daniela Cabral de , Pestana Mielle Silva , Silva Filho Sérgio Santos , Sperotto Lucas , Obana Fernando
Published: October 2022

É apresentado um estudo sobre o Agronegócio 4.0 (Agro 4.0) e sua evolução ao longo dos anos e, ainda, tecnologias como Internet das Coisas (IoT), Big Data, Sensoriamento Remoto, Drones e Machine Learning estão sendo aplicados no Agro 4.0. São apresentados, também, os benefícios e desafios das tecnologias e estado da arte no Agro 4.0. O objetivo do trabalho é realizar uma pesquisa bibliográfica sobre o Agro 4.0 e identificar as principais tecnologias adotadas, bem como os benefícios e desafios das mesmas. Nessa revisão quali-quantitativa, as dissertações, as teses e os artigos foram selecionados nas bases de dados Scielo e Google Acadêmico, também foram selecionados livros para o desenvolvimento do trabalho. O presente estudo justifica-se pelo crescimento das tecnologias no Agro, com foco nos trabalhos do estado da arte da inteligência artificial nesse ramo. Nesse sentido, é possível concluir que o Agro 4.0 encontra-se em expansão e numa possível transição para o Agro 5.0.
Cuidados no tratamento de pacientes com infecção por Helicobacter Pylori: Revisão sistemática de literatura
Authors: Silva Marcello Alexandre de Sousa , Fonseca Pedro Henrique da Silva , Franco Jessyka Viana Valadares , Silva Tállysson Felipe Balsanulfo , Andrade Lara Almeida de , Varela Giselle Ghader , Barbosa Juliana Marinho , Menezes Iza Maria dos Reis , Barbosa João Pedro Cerqueira , Corrêa Júnior Lindonor Márcio
Published: October 2022

A “Helicobacter pylori” é uma bactéria localizada no estômago e tem resistência aos locais ácidos, dando energia suficiente para sua sobrevivência. Sendo das causas mais comuns de doenças gastroduodenal, a bactéria é responsável por uma elevada porcentagem de gastrite, refluxo gástrico, úlceras gástricas e gastroenterite. O objetivo o objetivo deste presente estudo foi informar os profissionais de saúde sobre a atenção e o cuidado no tratamento de pacientes com a Helicobacter Pylori, apresentando o que se trata a bactéria, formas de exames para obtenção do diagnóstico e o tratamento. A pesquisa foi realizada por meio de revisões bibliográficas de materiais que se encontram em bases de dados científicas, com estudo descritivo, fazendo análise de dados minuciosos para a resolução da problemática e hipóteses em estudo. As informações serão levantadas pelo método documental através de artigos de natureza qualitativa. Contudo, os estudos destacaram que o paciente pode sentir algumas reações em casos de úlceras pépticas ou gastrite provocadas pela contaminação da bactéria o seu desenvolvimento ocorre na camada mucosa que protege o revestimento gástrico, região que tem menos exposição aos sucos ácidos gerados pelo estômago. O tratamento para erradicar a bactéria é classificado em primeira linha que dura por 14 dias. Já a terapia de segunda linha é realizada de 10 a 14 dias, podendo haver a substituição da claritromicina por levofloxacino.
GAGASAN HAK INGKAR DALAM PELAKSANAAN JABATAN NOTARIS DI INDONESIA: STUDI ANALISIS DAMPAK PUTUSAN MAHKAMAH KONSTITUSI NO. 49/PUU.X/2012
Authors: Fidhira Fitrah , Bakry Mohammad Ryan , Yusuf Chandra
Published: October 2022

Notaris dalam menjalankan jabatannya berdasarkan pasal 16 ayat (1) huruf f Undang-Undang Nomor 30 Tahun 2004 mempunyai kewajiban untuk merahasiakan isi Akta, Putusan Mahkamah Konstitusi Nomor 49/PUU.X/2012 memberikan dasar bahwa pasal 66 bertentangan dengan Undang-Undang Dasar Pasal 27 ayat (1) dan Pasal 28D (1). Konsekuensi logis putusan ini yakni terbukanya argumentasi perihal konsep dan penerapan hukum hak ingkar dalam pelaksanaan jabatan Notaris. Penelitian ini menggunakan metode penelitian hukum normatif dengan pendekatan statute dan analytical jurisprudence. Analisis dilakukan terhadap Putusan Mahkamah Konstitusi Nomor 49/PUU.X/2012 dan Undang-Undang Jabatan Notaris Nomor 30 Tahun 2004. Hasil analisis menemukan bahwa: Pertama, Pasca dikeluarkannya Putusan Mahkamah Konstitusi Nomor 49/PUU.X/2012, maka Undang-Undang Jabatan Notaris Nomor 30 Tahun 2004 perihal hak ingkar, dapat dikecualikan  jika berkaitan dengan due Process of law, akibat hukumnya adalah pemanggilan seorang Notaris tidak memerlukan lagi persetujuan Majelis Pengawas Daerah; Kedua, secara konseptual terdapat dua substansi utama yang menjadi argumentasi penting pasca-putusan Mahkamah Konstitusi Nomor 49/PUU.X/2012, yaitu prinsip equal before the law akan sejalan dengan prinsip due process of law, dan perlakuan yang berbeda terhadap jabatan Notaris yang mengedepankan peran Majelis Pengawas Daerah harus dipahami dalam kerangka Kode Etik Notaris, bukan pada tataran fungsi peradilan.
A szabad akarat győzelme a determinizmus fölött a Harry Potter regénysorozatban
Authors: Belovari Anita
Published: October 2022

A jó szöveg egyik ismérve, hogy számos értelmezési lehetőséget nyújt. A jó gyermekregény esetében ez lehetőséget nyújt az értő-értelmező, kritikai gondolkodás megalapozásához, amely a gyermekek számára nemcsak tanulmányaik során, de későbbi, felnőtt életükben is nagyon fontos. A Matthew Lipman által kezdeményezett gyermekfilozófiai irányzat mindezt úgy fogalmazta meg: tanítsuk meg a gyermekeket filozofikusan gondolkodni. Bár ez nem konkrétan a filozófiai problémák felvetését feltételezi egy iskolai tanórán, a Harry Potter történetesen erre is módot nyújt. Tanulmányomban egy filozófia kérdést kísérlek meg bemutatni a regény ilyen szemszögű elemzése segítségével: a determinizmus és a szabad akarat elméleteinek egybevetésével. A determinizmus tagadja a szabad akaraton alapuló döntés lehetőségét, hangsúlyozva, hogy minden történést előrevetítenek az azt megelőző körülmények, személyek esetében a hatások, amelyek a személyt érik. A szabad akarat nézet követői vitatják ezt a megközelítést, amely véleményük szerint kizárja a felelősség létezését, hiszen ha minden a szándékunkon kívül, már előre eldönthetik, akkor nem is lehetünk felelősek a tetteinkért. A Harry Potter-regénysorozatban ez a két, egymásnak ellentmondó vélemény sokoldalú, komplex rétegzettségben jelenik meg, ugyanakkor a gyermeki fejlettségnek, képzelet is érthető módon, szórakoztatóan kifejtve. Tökéletesen alkalmas a „filozófiai” gondolkodás megalapozására.
Decomposition of Natural Numbers from Prime Objects
Authors: Sebata Junya
Published: October 2022

We decompose natural numbers from structure which prime numbers have, as its starting point. With the decomposition, we can find a general law by categorization, which is in a power set and also in structure which prime numbers have, and we know that it limits the framework of structure about product and sum of natural numbers. In other words, $\sum_{k=1}^{n} \phi (k) \times [\frac{n}{k}] = \frac{n(n+1)}{2}$ holds, and it is equivalent to a basic formula of sum of divisors $\sum_{k|n} \phi (k) = n$.
SEKOLAH SIAGA BENCANA DESA SAMBONGBANGI KECAMATAN KRADENAN KABUPATEN GROBOGAN
Authors: LEGOWO Budi , WAHYUNINGSIH Daru , MULYANI Sri
Published: October 2022

Desa Sambongbangi, Kecamatan Kradenan, Kabupaten Grobogan merupakan dataran rendah dengan ketinggian rata-rata 54 mdpl. Secara geohidrologi masuk dalam rangkaian pegunungan kapur utara. Edapan kapur mendominasi lapisan pada kedalaman Â± 50 meter di bawah permukaan tanah. Hal tersebut menyebabkan potensi bencana kekeringan, pergerakan tanah dan kebakaran sangat besar. Sekolah Siaga Bencana (SSB) merupakan upaya membangun kesiapsiagaan sekolah terhadap bencana dalam rangka menggugah kesadaran seluruh unsur dalam bidang pendidikan baik individu maupun kolektif di sekolah dan lingkungan sekolah baik itu sebelum, saat maupun setelah bencana terjadi. Upaya mitigasi bencana dengan sasaran siswa sekolah dasar dengan usia 6-12 tahun diharapkan dapat menjadi prilaku dan karakter siaga bencana. Implementasi sekolah siaga bencana dilakukan dengan cara: 1. Pendampingan Integrasi Kurikulum; 2. Pelatihan guru kelas; 3. Simulasi siswa dan; 4. Pembuatan perangkat kesiapsiagaan bencana berupa buku petunjuk dan tanda evakuasi. Hasil P2M menunjukkan bahwa: 1. Keberdayaan masyarakat (Guru dan Siswa Sekolah Dasar Desa Sambongbangi Kecamatan Karadenan Kabupaten Grobogan masih perlu ditingkatkan; 2. Kemampuan integrasi kurikulum pengurangan resiko bencana; utamanya kebakaran, tanah longsor dan gempa  masih perlu ditingkatkan, dan 3. Metode simulasi cocok digunakan dalam integrasi kurikulum Pengurangan Resiko Bencana (PRB).
PELATIHAN DALAM PENGGUNAAN INFORMED CONSENT PADA FASILITAS PELAYANAN KESEHATAN
Authors: Setiyoargo Arief , Marbun Romaden , Maxelly Richard One
Published: October 2022

This Community Service activity aims to improve the quality of health services through understanding the use of informed consent. This activity begins with an initial assessment of the current state of the field in health care facilities through health workers/health cadres and residents. The initial assessment found that there was still a lack of public knowledge about medical treatment for patients and knowledge related to the use of informed consent in health facilities, especially during the current Covid-19 pandemic, the focus of health services is still centered on health protocols or physical distancing. The activity begins with preparing a plan and schedule of activities as well as the necessary equipment. The form of activities is packaged in the form of materials and videos that are shared via Google Drive online via WhatsApp groups. The activity ended with an evaluation using a google form. The results of community service activities there are as many as 57,69% of citizens' understanding in the good category, 26,92% sufficient and 15,38% less. Activities are going well and need further monitoring.
 
Kegiatan Pengabdian kepada Masyarakat ini bertujuan untuk meningkatkan kualitas pelayanan kesehatan melalui pemahaman penggunaan informed consent. Kegiatan ini diawali dengan penilaian awal kondisi terkini di lapangan di fasilitas pelayanan kesehatan melalui petugas kesehatan/kader kesehatan dan warga. Asesmen awal menemukan masih kurangnya pengetahuan masyarakat tentang penanganan medis bagi pasien dan pengetahuan terkait penggunaan informed consent di fasilitas kesehatan terutama pada masa pandemi Covid-19 saat ini, fokus pelayanan kesehatan masih berpusat pada kesehatan. protokol atau jarak fisik. Kegiatan diawali dengan penyusunan rencana dan jadwal kegiatan serta perlengkapan yang diperlukan. Bentuk kegiatan dikemas dalam bentuk materi dan video yang dibagikan melalui google drive secara online melalui grup WhatsApp. Kegiatan diakhiri dengan evaluasi menggunakan google form. Hasil kegiatan pengabdian masyarakat terdapat sebanyak 57,69% pemahaman warga dalam kategori baik, 26,92% cukup dan 15,38% kurang. Kegiatan berjalan dengan baik dan perlu pemantauan lebih lanjut.
PEMANFAATAN BUKU ILUSTRASI BERBASIS KEARIFAN LOKAL SEBAGAI MEDIA LITERASI DI TAMAN BACA KESIMAN
Authors: Suciartini Ni Nyoman Ayu , Kurniarini Ni Nyoman Yunika , Dewi Ni Luh PT. Putriyani , Brahman I Made Adi
Published: October 2022

This community service includes the use of illustration books based on local wisdom as a literacy medium at the Taman Baca Kesiman with the breath of literacy as a benchmark. Religious literacy is a priority program at the Directorate General of Hindu Guidance, to welcome the year of tolerance 2022. Given this, efforts are needed to strengthen literacy and insight into religion. Literacy is not enough to be interpreted as merely reading and writing activities, but requires critical thinking skills in assessing scientific sources in print, visual, digital, and auditory forms which are expected to be able to develop a literate and moderate attitude. The purpose of this service activity is to provide media for Hindu religious literacy based on local wisdom to visitors and staff in the Taman Baca Kesiman environment, explore local wisdom based on Hinduism which will be illustrated both digitally and in print, and visitors and management staff at Taman Baca Kesiman have media Hindu religious literacy based on local wisdom. The method of implementing the activity is the presentation method, namely the presentation of material from resource persons with deepening of material related to basic knowledge of literacy, religious literacy, understanding the local wisdom of Tri Hita Karana, as well as training by using illustration books based on Balinese local wisdom as literacy media.

 

Pengabdian masyarakat ini memuat pemanfaatan buku ilustrasi berbasis kearifan lokal sebagai media literasi di Taman Baca Kesiman dengan napas literasi sebagai tolok ukurnya. Literasi agama adalah program prioritas di Ditjen Bimas Hindu, untuk menyambut tahun toleransi 2022. Mengingat hal tersebut, diperlukan upaya-upaya untuk memperkuat literasi dan wawasan dalam beragama. Literasi tidak cukup hanya dimaknai dengan hanya sekadar kegiatan  membaca dan  menulis,  namun menuntut  adanya keterampilan berpikir kritis dalam menilai sumber-sumber ilmu baik dalam bentuk cetak, visual, digital, dan auditori yang diharapkan mampu mengembangkan sikap literat dan moderat. Tujuan kegiatan pengabdian ini untuk memberikan media literasi agama Hindu berbasis kearifan lokal kepada pengunjung dan staf di lingkungan Taman Baca Kesiman, menggali kearifan lokal berbasis agama Hindu yang akan dibuatkan ilustrasi baik secara digital maupun cetak, dan pengunjung dan staf pengelola di Taman Baca Kesiman memiliki media literasi agama Hindu berbasis kearifan lokal. Adapun metode pelaksanaan kegiatan yaitu dengan metode presentasi yaitu pemaparan materi dari narasumber dengan pendalaman materi terkait pengetahuan dasar literasi, literasi agama, pemahaman kearifan lokal Tri Hita Karana, serta pelatihan dengan memanfaatkan buku ilustrasi berbasis kearifan lokal Bali sebagai media literasi.
Factors Affecting Dividend Policy in Financial Sector Companies in Indonesia: Panel Data Analysis
Authors: Nur Syamsiyah  , Wulandari
Published: October 2022

This study aims to analyze the factors that influence dividend policy in financial sector companies in Indonesia. The independent variables in this study are profitability, leverage, managerial ownership, and firm size. While the dependent variable used is dividend policy. Findings. The results showed that simultaneously all independent variables (leverage, firm size, profitability, and managerial ownership) affected dividend policy (the dependent variable). The percentage of influence of all variables used in this study on dividend policy is 72.52%. At the same time the rest is influenced by other variables equal to 27.48%. Partially, profitability and firm size have a positive relationship to dividend policy.
Measuring Determination of Factors Affecting Firm Value in Agricultural Sector Companies in Indonesia
Authors: Ardana Yudhistira , Lestari Etty Puji
Published: October 2022

The purpose of this study is to use a panel data model to examine the factors that impact firm value in agriculture sector enterprises in Indonesia. Management initiatives such as earnings management, tax evasion, and debt strategy all influence business value. According to the findings of this study, all variables studied (earnings management, tax evasion, and debt policy) have an impact on business value. All of these variables have a 79.34 percent impact on the company's valuation, with the remaining 20.46 percent impacted by variables outside of the model. Meanwhile, independent studies show that debt and management strategies have little influence and have a negative link with business value. The study's findings may give more information on what elements may be included in measuring business value, which may have implications for investors, particularly those in agriculture sector companies listed on the stock exchange.
Teacher Educators and Trainee Teachers' Attitude toward Online Teacher Education Courses
Authors: Ahmed Md. Meraz , Md. Rokonuzzaman  , Hossain Md. Kamal
Published: October 2022

The purpose of the study was to explore the attitude toward Online Teacher Education Courses (OTECs). To that end, this study was carried out over the teacher educators and trainee teachers of Bangladesh Open University. Here, teacher educators represent the faculty members of the School of Education (SoE) of Bangladesh Open University (BOU), and trainee teachers represent the Master of Education (M.Ed.) and Bachelor of Education (B.Ed.) students of BOU. A mixed research approach with triangulation was used to conduct the study with a descriptive survey, two Focus Group Discussions (FGDs), and one key personnel interview. Data were collected from a total of 602 teacher trainees (182 were M.Ed. students and 420 were B.Ed. students) and 12 teacher educators, selected through multiple sampling techniques. The  data revealed that the teacher educators and trainee teachers had a positive attitude towards online courses since the mean score of faculty members, M.Ed., and B.Ed. students of BOU were 3.60, 381, and 3.81, respectively. Considering all these aspects, this study suggested that SoE/BOU needs to decide rationally to shape its future Online Teacher Education Courses (OTECs). This research contributes to the basement of new knowledge through an explorative study with all the possible stakeholders covering the whole country of interest.
Roadsides and neighboring field edges harbor different weed compositions
Authors: Simard Marie-Josée , Maheux Lydia
Published: October 2022

Roadsides are vectors of spread for invasive and other non-native plants. Therefore, fields located along roadsides could harbour more weeds and less native species compared to more isolated fields. To determine if field edges that are close to roadsides have different floras compared to more isolated fields, we surveyed 26 field pairs (52 fields) located in the province of Québec, Canada. For each pair, one field could be directly accessed by a major paved road (AD fields) while the other field, located on the same farm, was more isolated (IS fields) and could only be accessed via a secondary farm road. Two borders of these fields (IS) were sampled as well as the parallel (AD-pa) and the perpendicular border (AD-pe) of A fields and the adjacent roadside (RO). Plant species present along these field borders were recorded and classified (e.g. non-native, native, monocot, dicot, annual, perennial) in 0.5 m2 quadrats located every 20 m. The number of common ragweed (Ambrosia artemisiifolia) plants was also noted. Analyses included linear mixed models, generalized estimating equations models and multiple correspondence analyses. All border types had equivalent species richness. Roadsides had higher densities of common ragweed and lower occurrences of native and perennial species compared to field edges. All analyses indicate roadside floras are different from field edge floras but field edges close to roadsides were similar to those of more isolated fields. Results do not support a simple diffusive spread of roadside plants into field crop edges since field edges located along roadsides did not harbour more common ragweed plants or more roadside species.
The r1 relaxivity and T1 imaging properties of dendrimer-based manganese and gadolinium chelators in magnetic resonance imaging
Authors: Liu Kai , Liu Changcun , Xia Jindong
Published: October 2022

We report the preparation and characterization of gadolinium (Gd)- or manganese (Mn)-loaded dendrimers and Gd-loaded dendrimer-entrapped gold nanoparticles (Gd-Au DENPs) to examine the relationship between the number of metal ion chelators and r1 relaxivity. In this study, amine-terminated fifth-generation poly(amidoamine) dendrimers (G5.NH2) modified with different numbers of DOTA-NHS chelators were used to chelate Gd and Mn ions. The remaining amine groups were then acetylated completely, followed by the use of materials with better r1 relaxivities and T1-weighted imaging performances as templates to synthesize Gd-Au DENPs. The Gd and Mn chelators as well as Gd-Au DENPs were characterized via different techniques. We show that the r1 relaxivity and T1 imaging performance increase with loading of greater numbers of Gd and Mn ions on the G5.NH2 and that the acetylation process affects the relaxivity and imaging properties to a certain extent. After entrapment with Au NPs, the r1 relaxivity and T1-weighted imaging performance of Gd-Au DENPs decrease with greater loading of Au NPs. This systematic study of the relaxivities and T1-weighted imaging performances of Gd, Mn, and Gd-Au DENP chelators are expected to be a theoretical basis for developing multifunctional dual-mode contrast agents.
Isolipoic acid-linked gold nanoparticles bearing the thomsen friedenreich tumor-associated carbohydrate antigen: Stability and in vitro studies
Authors: Mondal Utpal K. , Barchi Joseph J.
Published: October 2022

We have previously prepared gold nanoparticles (AuNPs) bearing the Thomsen-Friedenreich antigen disaccharide (TFag), a pan-carcinoma, Tumor-Associated Carbohydrate Antigen (TACA), as tools for various assays and biological applications. Conjugation to AuNPs typically involves the use of thiols due to the affinity of sulfur for the gold surface of the nanoparticle. While a use of a single thiol-containing ligand bound to the gold surface is standard practice, several studies have shown that ligands bearing multiple thiols can enhance the strength of the conjugation in a nearly linear fashion. (R)-(+)-α-Lipoic acid (LA), a naturally occurring disulfide-containing organic acid that is used as a cofactor in many enzymatic reactions, has been used as a linker to conjugate various molecules to AuNPs through its branched di-thiol system to enhance nanoparticle stability. We sought to use a similar system to increase nanoparticle stability that was devoid of the chiral center in (R)-(+)-α-lipoic acid. Isolipoic acid, an isomer of LA, where the exocyclic pentanoic acid chain is shifted by one carbon on the dithiolane ring to produce an achiral acid, was thought to act similarly as LA without the risk of any contaminating (L)-(−) isomer. We synthesized AuNPs with ligands of both serine and threonine glycoamino acids bearing the TFag linked to isolipoic acid and examined their stability under various conditions. In addition, these particles were shown to bind to Galectin-3 and inhibit the interaction of Galectin-3 with a protein displaying copies of the TFag. These agents should prove useful in the design of potential antimetastatic therapeutics that would benefit from achiral linkers that are geometrically linear and achiral.
Recovery of carbon and cryolite from spent carbon anode slag of electrolytic aluminum by flotation based on the evaluation of selectivity index
Authors: Wang Yemin , Wang Xuexia , Bilal Muhammad
Published: October 2022

One of the main electrolytic aluminum production costs is the consumption of carbon anodes, and carbon anode slag is a common hazardous waste in the aluminum industry. In this work, electrolytic aluminum carbon anode slag was separated by flotation. Using the selectivity index (SI) as an indicator, the influencing factors of the carbon slag flotation process were optimized, and the separation performance of carbon and cryolite in the carbon anode slag was investigated. The raw carbon anode slag was ground for 40 min to achieve dissociation of the cryolite from the carbon, the optimized SI value was then used to determine the optimal flotation test conditions. The test results showed that the SI value under the optimal grinding flotation was approximately four times larger than the value of direct flotation. This indicated that carbon anode slag had a better flotation selectivity under the grinding flotation, which significantly improved the flotation performance.
Potential applications for climate services originated from the CLIMAX project
Authors: Cavalcanti Iracema F. A. , Coelho Caio A. S. , Rezende Luiz Felipe , Gomes Jorge L. , von Randow Celso
Published: October 2022

CLIMAX (Climate Services Through Knowledge Co-Production: A Euro-South American Initiative For Strengthening Societal Adaptation Response to Extreme Events) was an international project funded by FAPESP-Belmont forum developed during the 2016–2021 period. Germany, France, Netherlands, Argentina/France and Brazil were the international partners who worked in common objectives and tasks. The project was composed of four main Work Packages (WP), which interacted to achieve the final goal of developing potential applications to climate services. Here, some of the researches and results conducted by the team in Brazil, aiming at the application by climate services in several sectors, mainly in the energy sector are presented, some including international partners collaborations. The WP0—Co-design and Co-Production of Knowledge, was developed in collaboration with the energy sector, the National Operator of Electric System (ONS). Climate research activities were conducted through interactions between climate researchers, energy sector personnel and social scientists, focusing on applications. WP1—Physical processes explaining climate variability in South America, aimed to study the remote and regional features associated with precipitation extremes over South America, with emphasis on regions where the main hydrographic basins are located. WP2—Predictability and Prediction tools developed several studies, mainly at the sub-seasonal timescale, which was a timescale identified to be useful for ONS. WP3—Social processes explaining climate information appropriation was composed of social scientists and had the mission of producing a characterization of the electric sector. Here, some of the WP1 and WP2 results are summarized, illustrating the potential applications. WP0 and WP3 results are presented in other papers.
Electrocardiographic criteria for localization of ventricular premature complexes from the inferior right ventricular outflow tract
Authors: Li Kang , Lv Pinchao , Wang Yuchuan , Fan Fangfang , Ding Yansheng , Li Jianping , Zhou Jing
Published: October 2022

Background

The ventricular premature complexes (PVCs) originating from the superior right ventricular outflow tract (RVOT) have high success rates by catheter ablation. It may not be the same when the origin is in the inferior RVOT.

Objective

To identify electrocardiographic (ECG) characteristics that predict the site for successful ablation of PVCs originating in the inferior RVOT.

Methods

Of 309 consecutive patients with symptomatic PVCs despite medical therapy, 124 had PVCs originating from the RVOT, and 107 RVOT cases without structural heart disease and no bundle branch block in sinus rhythm were enrolled in the study. Among them, 74 have a superior RVOT origin, and 33 have an inferior RVOT origin.

Results

The proportion with multiple morphologies of PVC was significantly higher in the inferior RVOT group than in the superior RVOT group (24.24 vs. 6.76%, P = 0.011). The QRS duration of PVCs with an inferior RVOT origin was more expansive than PVCs with a superior RVOT origin (162.42 ± 19.69 ms vs. 140.90 ± 11.30 ms; P < 0.001). Furthermore, the QRS wave in V1 in patients in the inferior RVOT group was more likely to have a negative delta wave at the onset of the QRS (27.27 vs. 1.39%, P < 0.001). We found that the areas under the receiver-operating characteristic curve (AUCs) for PVC diagnosis with an inferior RVOT origin ranged from 0.812 to 0.841 depending on ECG features, with the highest AUC for the QRS duration of PVCs and the amplitude of R waves in lead II. These ECG indices had good predictability for judging the origin of PVCs in the RVOT; the best threshold for the QRS duration of PVCs was 145 ms, and the best thresholds for the amplitude of R waves in leads II, III, and aVF were 1.35, 1.35, and 1.15 mV, respectively.

Conclusion

When evaluating a patient with PVCs, the source is likely to be the inferior RVOT if the ECG presentation conforms to the morphological characteristics of the RVOT, meanwhile, the QRS wave is relatively broad and polymorphic, and the main waves in limb leads (II, III, and aVF) are upward with low amplitude.
Human embryonic stem cell-derived endothelial cell product injection attenuates cardiac remodeling in myocardial infarction
Authors: Spiroski Ana-Mishel , McCracken Ian R. , Thomson Adrian , Magalhaes-Pinto Marlene , Lalwani Mukesh K. , Newton Kathryn J. , Miller Eileen , Bénézech Cecile , Hadoke Patrick , Brittan Mairi , Mountford Joanne C. , Beqqali Abdelaziz , Gray Gillian A. , Baker Andrew H.
Published: October 2022

Background

Mechanisms contributing to tissue remodeling of the infarcted heart following cell-based therapy remain elusive. While cell-based interventions have the potential to influence the cardiac healing process, there is little direct evidence of preservation of functional myocardium.

Aim

The aim of the study was to investigate tissue remodeling in the infarcted heart following human embryonic stem cell-derived endothelial cell product (hESC-ECP) therapy.

Materials and methods

Following coronary artery ligation (CAL) to induce cardiac ischemia, we investigated infarct size at 1 day post-injection in media-injected controls (CALM, n = 11), hESC-ECP-injected mice (CALC, n = 10), and dead hESC-ECP-injected mice (CALD, n = 6); echocardiography-based functional outcomes 14 days post-injection in experimental (CALM, n = 13; CALC, n = 17) and SHAM surgical mice (n = 4); and mature infarct size (CALM and CALC, both n = 6). We investigated ligand–receptor interactions (LRIs) in hESC-ECP cell populations, incorporating a publicly available C57BL/6J mouse cardiomyocyte-free scRNAseq dataset with naive, 1 day, and 3 days post-CAL hearts.

Results

Human embryonic stem cell-derived endothelial cell product injection reduces the infarct area (CALM: 54.5 ± 5.0%, CALC: 21.3 ± 4.9%), and end-diastolic (CALM: 87.8 ± 8.9 uL, CALC: 63.3 ± 2.7 uL) and end-systolic ventricular volume (CALM: 56.4 ± 9.3 uL, CALC: 33.7 ± 2.6 uL). LRI analyses indicate an alternative immunomodulatory effect mediated via viable hESC-ECP-resident signaling.

Conclusion

Delivery of the live hESC-ECP following CAL modulates the wound healing response during acute pathological remodeling, reducing infarct area, and preserving functional myocardium in this relatively acute model. Potential intrinsic myocardial cellular/hESC-ECP interactions indicate that discreet immunomodulation could provide novel therapeutic avenues to improve cardiac outcomes following myocardial infarction.
Associations between serum 25-hydroxyvitamin D, body mass index and body fat composition among Emirati population: Results from the UAE healthy future study
Authors: AlAnouti Fatme , Ahmad Amar Sabri , Wareth Laila Abdel , Dhaheri Ayesha Al , Oulhaj Abderrahim , Junaibi Abdulla Al , Naeemi Abdullah Al , Hamiz Aisha Al , Hosani Ayesha Al , Zaabi Eiman Al , Mezhal Fatima , Maskari Fatma Al , Alsafar Habiba , Yaaqoub Jamila , Bastaki Marina Al , Houqani Mohammed Al , Oumeziane Naima , Juber Nirmin F. , Sherman Scott , Shah Syed M. , Alsharid Teeb , Zaabi Thekra Al , Loney Tom , Mahmeed Wael Al , Abdulle Abdishakur , Ali Raghib
Published: October 2022

Introduction

Vitamin D deficiency and insufficiency are highly prevalent among several populations across the globe. Numerous studies have shown a significant correlation between body-mass-index (BMI) and Vitamin D status, however, some results differed according to ethnicity. Despite the abundance of sunshine throughout the year, vitamin D deficiency is prominent in the United Arab Emirates (UAE). In this study, we analyzed the UAE Healthy Future Study (UAEHFS) pilot data to investigate the association between serum 25-hydroxyvitamin D (25(OH)D) and % body fat (BF) composition as well as BMI.

Material and methods

Data from a total of 399 Emirati men and women aged ≥ 18 years were analyzed. Serum 25(OH)D and standard measures of weight and height were included in the analyses. Vitamin D deficiency was defined as serum 25(OH)D concentration<20 ng/ml. Multivariate quantile regression models were performed to explore the relationship between serum 25(OH)D levels and % BF composition and BMI correspondingly.

Results

There were 281 (70.4%) males and 118 (29.6%) females included in this study. More than half of the study participants had vitamin D insufficiency (52.4%), and nearly a third had vitamin D deficiency (30.3%); while only 17.3% had optimal levels. A statistically significant negative association between serum 25(OH) D levels and % BF composition was observed at intermediate percentiles while a statistically significant negative association between serum 25(OH)D and BMI was only observed at the median (50th percentile).

Conclusion

The study findings support the association between low serum 25(OH) D levels (low vitamin D status) and high % BF composition and high BMI among adult Emiratis. Further longitudinal data from the prospective UAEHFS could better elucidate the relationship between serum 25(OH) D levels, % BF composition, and BMI in the context of various health outcomes among this population.
The dominant role of aerosol-cloud interactions in aerosol-boundary layer feedback: Case studies in three megacities in China
Authors: Xiong Changrui , Li Jing , Liu Zhenxin , Zhang Zhenyu
Published: October 2022

Interactions between aerosols and meteorology have received increasing attention in recent decades. Through interactions with radiation, aerosols involve in thermodynamic processes and cause cloud adjustment, referred to as the direct and semi-direct effects respectively. They also involve in cloud microphysical processes by severing as cloud condensation nuclei or ice nuclei, referred to as indirect effect. Aerosol direct effect is found to potentially exacerbate air quality by stabilizing the planetary boundary layer (PBL). However, their impacts through the interaction with clouds, including semi-direct and indirect effect remain unclear. In this study, we conducted model simulations to evaluate the direct, semi-direct and indirect effects of aerosols in PBL structure and surface PM2.5 concentration during three heavy haze events under overcast conditions. Overall, the aerosol-PBL feedback results in a 22%–36% decrease of PBL height and 5%–28% increase of PM2.5 concentration. The indirect effect always has the largest impact on PBL and PM2.5 pollution, accounting for 59%–84% of the changes. The semi-direct effect is the weakest on average, although it can exceed the direct effect at certain times and locations. Black carbon aerosols play the vital role in both the direct and semi-direct effects. Our findings promote the understanding of heavy haze formation, and highlight the dominant role of aerosol-cloud interaction in the feedback process of aerosols to PBL structure and air quality.
Does the marketization of land transfer have an impact on carbon emissions? Evidence from China
Authors: Zhang Ruigang , Yang Runze , Huang Yu
Published: October 2022

Excessive carbon emissions caused by extensive economic development are the key to the current government’s carbon emission reduction goals. In the process of market-oriented reform of land transfer, alleviating the contradiction between land use and low-carbon development is an essential problem in achieving the purpose of carbon peaking and carbon neutrality. The impact of land transfer marketization on regional economic development is complex, and the final effect on carbon emissions needs to be further examined. Based on China’s provincial panel data from 2008 to 2017, this paper uses a double fixed effect model to conduct an empirical analysis. The lag effect of the initial regression results is tested, and the quantitative test of the mediating effect and moderating effect of fixed asset investment is also carried out. The following conclusions are drawn: Firstly, the improvement of the marketization of land transfer will promote carbon emissions; secondly, the promotion effect of the degree of marketization of land transfer on carbon emissions will become inhibited with the delay of the lag effect years. Moreover, fixed asset investment will play a masking effect and an adjustment effect; thirdly, the impact of the degree of marketization of land transfer on carbon emissions is different in the eastern and western regions divided by the degree of marketization, and the strength of government control will also have a significant impact on the impact. The research results of this paper enrich the economic impact theory of land transfer marketization and have certain value for regional land policy management in the context of carbon emission reduction.
Allocation and optimization of carbon emission permits considering fairness and efficiency under the dual-carbon background
Authors: Xiao Yong , Wu Leyou , Xie Pinjie , Pan Xianyou
Published: October 2022

Reasonable and effective allocation of carbon emission permits is one of the important tasks to achieve the goal of carbon neutrality. Based on the difference in carbon emission reduction contribution and capability of the industries, this paper proposes a carbon emission permits allocation and optimization scheme that take into account fairness and efficiency. First, based on fairness principle, establish a carbon emission quota system of the six industries and determine the index weights, and use the comprehensive index method to realize the initial allocation of carbon emission permits. Then, on the basis of evaluating the initial carbon emission permits allocation efficiency, based on efficiency principle, the zero sum gains data envelopment analysis (ZSG-DEA) model is used to iteratively obtain the optimal allocation scheme of carbon emission permits. Example analysis shows that the carbon permit allocation and optimization model based on fairness and efficiency principles proposed can realize the optimal allocation of industrial carbon emission permits, ensure the optimal efficiency of industrial carbon permit allocation, and provide adequate support for the carbon emission reduction decisions of the six industries.