bluuebunny/crossref_metadata_2025 huggingface dataset:
Value-based health care: alignment the tools and methods (literature review)
Authors: Kamynina Natalya N. , Polishchuk Nikita S.
Published: January 2023

The desire to solve the problem of efficient spending of funds in the public sector has been transformed into an understanding of values. The desire to reduce costs, maintain the proper quality and maximize the availability of medical care led to the emergence and formation of a new concept of effective functioning based on values - VBHC (Value-based Health Care). Purpose. To systematize the criteria, metrics and methods for evaluating effectiveness in the context of the VHBC concept. To obtain the necessary information, a selective literature review was carried out. Electronic bibliographic databases in Russian (“RSCI/eLibrary”) and English (“Pubmed”) were used. Search queries were formed taking into account the MeSH nomenclature. To determine the effectiveness of the provision of medical services and the implementation of government programs (projects) in general, there are a number of methods. First of all, it is an analysis of costs, benefits, effectiveness and benefits. The most applicable performance measure is Quality Adjusted Life Years. QALY is a universal indicator of any health program. This expression of “utility” is by default the ultimate goal (final target unofficial indicator) of any government management decision in health care. Assessing the effectiveness of health care and developing a value-based model of health care through cost-benefit analysis is a time-consuming and important task. The study showed that it is necessary to use multidimensional tools for assessing the effectiveness of medical care. Conclusions. As a result of the review, it was found that there is no unified information system that offers ready-made assessment tools, and metrics have not been developed to evaluate the effectiveness of value-based healthcare VBHC models. It seems possible to create a checklist with universal parameters, implement it into a ready-made information system available on the market today to any medical institution, and analyze the effectiveness of the VBHC model based on the developed checklist.
Assessment of shifts in mortality age profile of adult population in Moscow during pandemic
Authors: Savina Anna A. , Zemlyanova Elena V. , Feyginova Svetlana I. , Tarasov Nikolai A.
Published: January 2023

Introduction. The COVID-19 pandemic induced the global crisis of mortality. Delayed medical care and reduced availability under quarantine restrictions have led to an increase in mortality not only from Covid-19, but also from chronic non-communicable diseases, affecting men and women of different ages to varying degrees. The study purpose is to assess shifts in mortality age profile of population aged 20+ in Moscow during COVID-19 pandemic. Materials and methods. Official vital statistics of Rosstat, operational information from civil registration database on death causes in Moscow. Results. The gain in mortality rate caused primarily by deaths from COVID-19 interrupted in 2020 the positive demographic dynamics that had developed over the previous years. In 2021, the increase in the mortality rate continued, but the loss of life expectancy was lower due to a decrease in mortality in older ages and the return of most indicators to the level of 2019. However, from a socio-economic point of view, the situation in 2021 developed more negatively, since the age structure of life expectancy losses is younger than in 2020. Limitations. The study results are based on operational information of the Moscow civil registration office and could be used for the development of managerial decisions for Moscow only. Conclusion. Against the pandemic demographic situation in Moscow has worsened. Due to mortality gain in the Russia’s capital first in the past years recorded natural population decline.
Principles of laboratory service management in modern conditions
Authors: Tsibin Alexander N. , Latypova Munira F. , Komarov Andrew G. , Slutsky Egor A. , Ivanushkina Olga I.
Published: January 2023

Introduction. Today, the medical laboratory is focused on operational efficiency and cost control. Our work presents the experience of transforming laboratory practice, its informatization and reorganization of the management model. Purpose of the study. Creation of a management model for fast, economical and high-quality testing in laboratories of various levels to provide Muscovites with laboratory services in full. Materials and methods. An assessment of the resource support of clinical diagnostic laboratories (CDL) of the Moscow City Health Department (MCHD) number of attached population and the need for tests, made it possible to develop and implement concepts for their centralization in the outpatient clinic link, unify the nomenclature of laboratory studies and tests, create a unified reference book of laboratory studies (IF) for the centralized laboratory service (CLS) of the unified medical information and analytical system (UMIAS), develop a plan for the development of a quality management system based on international standards and begin the activity on the standardization of laboratory services through accreditation of medical laboratories in the national accreditation system, manage centralized large-scale screening for SARS-CoV-2; implement sequencing technology (NGS) for genomic surveillance. Results. The MCHD laboratory service is built according to a 3-level system. There is a complex IF EMIAS. Laboratory studies are computerized, test results are transferred to the personal account and the patient’s electronic medical record. A single information space has been created for all CDL MCHD. The tariffs for laboratory services of the registry of the Moscow City Compulsory Medical Insurance Fund (MCCMIF) have been changed, the list has been optimized. Under the control of spending, the productivity of laboratories has increased. Moscow’s needs for laboratory services have been met. Research limitations. The scenario of managerial approaches was carried out in a strategic partnership with MCHD, proved to be viable only in the conditions of the city of Moscow. Conclusion. The problems of precision medicine have been solved and the sustainable provision of laboratory services to the population by the clinical diagnostic laboratories of the MCHD has been ensured.
Comprehensive analysis of the trend in main indicators of the health of the adult population suffered from chronic non-communicable diseases with the preventive activity of medical institutions
Authors: Zaikina Inna V. , Komleva Nataliia E. , Mazilov Svyatoslav I. , Dolich Vladimir N. , Medentsov Vyacheslav A.
Published: January 2023

Purpose. The relevance of the study is determined by the high incidence of chronic non-communicable diseases (CNCD) and the mortality of the working population. Materials and methods. As part of an observational study, morbidity and mortality due to CNCDs in the adult population of the Saratov region, the trend in the medical examination index and medical prevention activity over 2011-2020 were analyzed. Results. Analysis of trends in morbidity and mortality due to chronic NCDs for 2011-2020 showed the gain. Respiratory diseases are leading in their structure (chronic bronchitis, emphysema - an increase by 200 cases (+200%), obstructive pulmonary disease - 200 (+50%), asthma - 0 (0%)), obesity - 100 (+62,5%), diseases of the circulatory system (DCS) - 1330 (+35,5%), diseases characterized by high blood pressure - 460 (+39,3%), coronary heart disease - 750 (+98,7%) cerebrovascular diseases - 190 (+19,6%); type II diabetes - 50 (+17,8%), malignant neoplasms - 50 (+12,2%). In the structure of total mortality the share of CNSD in 2011 was 51%, neoplasms - 12,6%, and in 2020, CNSD of tumor formations amounted to 49,4% and 12,6%, respectively. Increase in deaths due to neoplasms (15,8%), CNSD (12,2%) in 2020 compared to 2011, and compared to 2019 due to diabetes mellitus (+90.8%), diseases of the respiratory system (+44,4%), CSD (+17,2%), in particular, coronary heart disease (+27,7%), cerebrovascular diseases (+2,7%), malignant neoplasms (-1,6%). Limitations. The study has regional (Saratov region) limitations. Conclusion. Primary morbidity and mortality rates reflect an unfavourable prognosis for CNCDs in the adult population of the Saratov region. This justifies the analysis of health care and the development of highly effective methods of prevention and treatment and rehabilitation measures aimed at maintaining health and extending the working longevity of the population.
Clinical, laboratory and ultrasound characteristics of autoimmune thyroiditis in the children’s population of territories with the location of metallurgical enterprises
Authors: Shtina Irina E. , Luzhetsky Konstantin P. , Valina Svetlana L. , Zenina Marya T. , Ustinova Olga Yu.
Published: January 2023

Introduction. The combination of iodine deficiency and the negative impact of environmental factors determines the pathomorphism of thyroid diseases, including autoimmune thyroiditis (AIT). The purpose of the study was to establish clinical, laboratory, and ultrasound features of autoimmune thyroiditis in children living under the influence of metallurgical production. Materials and methods. AIT children residing in the zone of influence of the enterprises of the metallurgical industry (one hundred two cases) and outside the exposure zone (46 people) underwent a comparative analysis of the results of clinical and laboratory research, ultrasound imaging of thyroid gland tissues. Results. During the period 2010-2020, the increase in the incidence of thyroiditis in the territory with metallurgical production enterprises exceeded the average indicator in the Perm region by 1.5 times. Children from the test group had concentrations of lead, manganese, nickel, chromium and zinc in their blood higher than the regional background level. These elevated concentrations were detected in them by 1.7-5.5 times more frequent than in their counterparts from the reference group. The number of AIT cases elevated by 2 times in the exposed boys; diffuse lesions of the thyroid gland and combination of AIT with other diseases, by 1.3 times (p = 0.03-0.04). Levels of IgA and IgG in blood serum were by 2.7 times higher in the test group (p = 0.015-0.043); TSH contents, by 2.3 times higher (p = 0.096); free T4 contents, by 5.4 times lower (p = 0.057). Limitations of the study. Children living at the only one subject of the Russian Federation; a comparatively small sampling; selected study of compounds with direct thyreo-cytotoxic effects Conclusions. Incidence of thyroid gland diseases and thyroiditis in territories with developed metallurgic industry is higher than on territories with a relative favorable sanitary-hygienic situation. Children with elevated contents of metals in their blood had disorders of thyroid and immune status, thyroid gland disease and concomitant damage to other systems in the body. The mathematical relationships indicate the possible influence of metals on the formation of AIT.
Nasopharyngeal Relapse of Conjunctival Melanoma Four (04) Years after Complete Resection: About One (01) Case
Authors: Panandtigri Souleymane , Charkaoui Meryeme , Pierre Xavier Sia Nioka , Chekrine Tarik , Bourhafour Mouna , Bouchbika Zineb , Benchakroun Nadia , Jouhadi Hassan , Tawfiq Nezha , Sahraoui Souha , Abdellatif Abdellatif
Published: January 2023

Context: Malignant melanoma of the mucous membranes of the nasopharynx is extremely rare. Despite improved diagnostic capabilities, these lesions are often diagnosed at an advanced stage and the prognosis is poor, in part related to the high rate of recurrence and metastasis. Case Presentation: We report one (01) case of relapse of a malignant mucous melanoma of the nasopharynx, four (04) years after complete conjunctival resection in a fifty (50) year old woman. Before the signs of call for epistaxis, an X-ray workup performed showed a nasopharyngeal tumor, followed by surgical resection with bilateral cervical lymph node dissection. Histology reveals a malignant melanoma without lymph node involvement. Adjuvant radiotherapy was delivered. The control by emission of positron (PET) at six (06) months after the end of adjuvant treatment did not find any lesions. Conclusion: To our knowledge, this is the first case report of a diagnosis of nasopharyngeal melanoma after four (04) years of complete remission. In view of the aggressive high rate of recurrence and metastasis, close monitoring and radiological workup at the slightest sign of calling should be required. Thus, the diagnosis will be made at an early stage which could improve the prognosis.
Design, Development and Evaluation of Eucalyptol Transdermal Patch for Anti-Diabetic Activity
Authors: Shalini Perada, P.N. Murthy
Published: January 2023

For almost two hundred years, diabetes mellitus has been a major health problem worldwide. While there has been progress in our knowledge of its pathophysiology and treatment, the therapeutic choices available today are woefully inadequate. The goal of transdermal medication delivery systems is to provide therapeutically effective doses of a medicine via the skin. The medicine is released at a steady, regulated pace thanks to the design of these devices. As a result, it is well suited for the management of long-term conditions like diabetes. Thus, the risks and inconvenient nature of the oral and parenteral routes are avoided. The purpose of this study is to develop and test eucalyptol transdermal patches for the treatment of diabetes. Drug distribution from different polymer-based transdermal patches might be enhanced by using oleic acid as a penetration enhancer. Matrix-style transdermal patches, composed of PVP K30, HPMC K100, and solvent, were created utilizing solvent casting procedures. By using Fourier transform infrared spectroscopy, researchers were able to examine the drug's and polymers' physicochemical compatibility. No evidence of physical or chemical incompatibility between the medication and the polymers was found. The patches also underwent a battery of physical tests in addition to the in-vivo research. The patches with the polymers, that is, PVP K30, HPMC K100, and oleic acid as the penetration enhancer, were regarded the best formulations for the transdermal distribution of eucalyptol based on the findings obtained from the physical assessment, ex vivo investigations, and in-vivo studies.
THE PREPAREDNESS OF THE LIBRARIES OF THE FACULTIES OF CHEIKH LARBI TEBESSI UNIVERSITY IN TEBESSA-ALGERIA TO MEET THE INFORMATION NEEDS OF THE PARTIES TO DISTANCE EDUCATION
Authors: ZAIET Lilia
Published: January 2023

The study aims at researching the readiness of the libraries of the faculties of the university of cheikh larbi tebessi in tebessa-algeria to support the educational and research process by addressing the needs of the parties to distance education, which algerian universities have pursued for nearly three years as an alternative and then as a complement to attendant education. especially requests that are often vague, inconsistent and far from understandable. the strategy currently being adopted by the libraries under consideration and planned for future adoption was présentes in this study after the conceptual framework was defined. to this end, half-rated interviews were conducted with the governors of the libraries of the faculties of cheikh larbi tebessi university. bases on the study's findings, a proposes strategic profile has been developed. Keywords: Information Needs - Distance Education - Parties To Distance Education - Libraries of Faculties of Cheikh Larbi Tebessi University.
THE INTENTIONAL APPROACH IN JURISPRUDENCE IN THE TIME OF EPIDEMICS
Authors: Said Hamed ALAZRI Maryam
Published: January 2023

This paper aims to highlight the contributions of scholars in the consolidation of the intentional idea of activation and application in the jurisprudential approach in the facts of diseases and epidemics, which serves the system of jurisprudence in general and contributes to the formulation of a sober intentional jurisprudence research in the field of diseases and epidemics in the midst of suspicion and blurring of vision in this important issue in the life of The human being has been afflicted with affliction in this present time in the time of the Corona epidemic (Covid 19).. Keywords: The Intentional Approach; Jurisprudence; The Time of Epidemics
LA PROMOCIÓN INTEGRAL Y CREATIVA DE LA DIVERSIDAD COMO REQUISITO PREVIO PARA LA CONSTRUCCIÓN DE LA UNIDAD
Authors: Sánchez Zariñana José
Published: January 2023

Durante muchos siglos, la Iglesia católica se ha preocupado por promover la unidad, no solo dentro, sino fuera de ella. El Papa y los obispos juegan un rol muy importante en esta promoción, y de hecho una de sus funciones es la de ser garantes de la unidad tanto dentro de las Iglesias locales como en la Iglesia universal. Desgraciadamente, esto ha ido en detrimento del incentivo a la diversidad. Si esta diversidad no es plenamente respetada y debidamente fomentada, es imposible alcanzar una verdadera unidad. El reconocimiento de la diversidad es fundamental dentro de la evangelización eclesial —asumiendo que la diversidad no rompe con la unidad esencial de la Iglesia—, pues el mundo es cada vez más diverso, y las pluralidades en todas las dimensiones están reclamando su derecho a la existencia.
The Relation of Biomarkers in Serum Non-Alcohol Fatty Liver Disease with Diabetes Mellitus Type 2 and NAFLD Obese among Adults in Basrah Governorate
Authors: Latif Fatima J. Abdul , Al Sawafi Abeer G. , Ali Dawood S.
Published: January 2023

Non-alcoholic fatty liver disease (NAFLD) is the term for a range of conditions caused by a build-up of fat in the liver. The goal of the study was to determine the link between lipid damage (MDA), enzymatic and non-enzymatic antioxidants, and various biochemical indicators in patients with NAFLD who had diabetes and obese adults. This study included comparison 100 patients and healthy control group, aged 18 to 75 years while BMI range from 15.9 to 50.9 Kg/m2. Enzymatic antioxidants (superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx)); non-enzymatic antioxidants (GSH, vit E and direct and total bilirubin); lipid damage (malondialdehyde (MDA)), and biochemical markers (liver enzyme (ALT, AST & ALP), glucose, Albumin and lipid profile in the serum samples were measured. The NAFLD with DM and obese adult showed increasing of glucose, BMI, ALT, AST, ALP, T. CHOL, LDL, TG, VLDL, SOD and CAT levels excepted HDL. It showed a decreasing. Whereas decrease of Vitamin E and ALB levels compared to control group. Our findings show that the serum enzymatic anti-oxidant, non-enzymatic anti-oxidant, dyslipidemia and liver disfunction and vitamin E decrease are tightly and independently related to NAFLD with diabetes and obese adult status.
Investigation of Tritrichomonas Foetus in Cattle Using Different Methods in Basrah City – Iraq
Authors: Nasir Muntaha A. H. , S.R. Al-Idreesi , Al-Masoudi Wasfi A.
Published: January 2023

Tritrichomonas foetus causes a venereal disease in cattle called bovine trichomoniasis. T. foetus lives in the reproductive tract of the cow, the surface of the penis and prepuce of the bull and causing early fetal loss and sometimes late term abortions. It can also extend breeding / calving season. In this study, 155 cows of different ages (2-6 years old) and with a variety of clinical signs (repeat breeders, abortions, and discharge only) were examined from different areas in Basrah Province, Iraq from November 2020 to July 2021, and 75 samples collected from healthy animals (without any symptom). The infection rate was detected in wet mount techniques found fewer positive findings than in pouch techniques, with 12 (40%) recorded and in pouch systems, 30 (100%) recorded while in the culture 24(80 %), Giemsa-stained smears 19(63.3%) and Acridine orange was 20 (66.6%). The present study improved that cows more than three years are more susceptible to be infected than cows less than three years. The study concluded that if no control method is applied in Basrah, there is a serious risk of spreading Trichomonas foetus.
Semi – Automation Design Using Flow Injection Analysis System with Smart Phone for the Determination of Total Phenols in Wastewater
Authors: Ilaybi Hakeem Jabbar , Hussien Mustafa Abdulkadhim
Published: January 2023

Smart phone used as supporting hardware in different applications in chemical analysis are becoming increasingly important in everyday life. Rapid, easy, and straightforward analytical system flow injection analysis system for the determination of the total phenols was conducted using 4-aminoantipyrine reagent. The detection method was based on the reaction total phenols with reagent in the basic media and subsequent formation of a yellow color product. The samples or standard solutions were injection into a carrier stream to react with 4-aminoantipyrine reagent and ammonium chloride with ammonium hydroxide to give yellow color product, which was detected by spectrophotometer at 510 nm. The experimental condition such as flow rate of reagent and carrier, reagent volume, length of reaction coil and concentration of reagent were optimized. A good linear calibration curve in the range of 250-2000 mg L-1 was obtained with regression equation (y=0.0108 x + 0.3453), (R= 0.9989). The limit of detection was in the amount of 0.0112 mg L-1. The method was successfully applied for the determination of the total phenols in wastewater.
Politik Gerilim Sineması’ndan Bir Portre: ‘Z’ Filmi Bağlamında Bir Costa Gavras Analizi
Authors: ATAYMAN İpek Elif
Published: January 2023

Politika, toplumsal ilişkilerde önemli bir dağıtım mekanizmasıdır. Ancak tek başına, soyut bir olgu da değildir. Yöneten-yönetilen unsurlarının yanı sıra bu iki unsura etki eden faktör ve aktörlerin de sürece dahil olduğu gözlemlenmektedir. Bu temel karakterlerle ortaya konulan politik iletişim faaliyeti son yarım asırda çok çeşitli kaynaklarla yürütülmektedir. Söz konusu iletişim faaliyeti, politik sinema ile de yüzünü göstermektedir. Nasıl ki politika tüm yaşamları yakından etkileme kapasitesini bünyesinde barındırmaktadır; sinema da benzer şekilde aslında gündelik hayatın temel bir parçasıdır. Bu yüzden iki temel insan faaliyeti kimi zaman kolkola da yürümektedir.

Politik iletişim ve sinema ilişkisi içinde bir alt tür olarak politik gerilim de kendisine önemli bir yer bulmaktadır. Bu alt türün önemli temsilcilerinden birisi Constantinos (Costa) Gavras’tır. Gavras, çeşitli politik gerilim filmleriyle, yöneten-yönetilen ilişkisinde söylenilmeyi söylemeyi, eleştirilemeyeni eleştirmeyi uhdesine almış bir senarist ve yönetmen olmuştur. Bu makalede Gavras, 1969 yılında yönettiği ‘Z’ filmi örneğinde derinlemesine incelenmektedir. Gavras sineması, ‘Z’ filmi de olmak üzere tipik ürünlerinde, popüler kitle kültürünün algılarını dikkate alarak, bu seyirci algısının temel niteliklerini yok saymadan politik kaygılar dahilinde mesajını sinemalaştırmaya çalışmıştır.
Comparative Study on the Detection of Parkinson's Diseaseusing Machine Learning
Authors: Ms. Lolakshi  , Shrikara RM  , Kavya Kulkarni  , Farooq Abdullah  , Naveen Bhavani
Published: January 2023

Parkinson's disease is a progressive disorder that affects the nervous system and the parts of the body controlled by the nerves and the root cause of it is falling rates of dopamine levels in the forebrain. It is a chronic degenerative disease with progressive illness, which means it develops new symptoms over time, actually the average diagnosis time is above two years. The prediction of the Parkinson’s disease is the most challenging problem for the biomedical engineering researches and doctors.Due to the decrease in motor control that is the hallmark of the disease, voice can be used as a means to detect and diagnose PD. With advancements in technology and the prevalence of audio collecting devices in daily lives, reliable models that can translate this audio data into a diagnostic tool for healthcare professionals would potentially provide diagnoses that are cheaper and more accurate. We provide evidence to validate this concept here using a voice dataset collected from people with and without PD.
A Review of Blockchain-Based Supply Chain Management: Applications, Challenges and Research Opportunities
Authors: Mr. Pradeep V  , R Yajnesh  , Shreyas Moolya  , Shetty Yash  , Thirtha
Published: January 2023

Blockchain technology has the potential to transform supply chain management by providing traceability, transparency, efficiency, and security. This review paper aims to provide a comprehensive overview of the current state of research on the application of blockchain in supply chain management, and to identify the main challenges and opportunities of using blockchain in this context. The review is based on a selection of IEEE papers on the topic, including "A Framework for Blockchain-Based Supply Chain Management" by B. Zhang, J. Huang, and X. Liu, and "A Review of Blockchain Technology in Supply Chain Management" by Y. Guo, J. Zhang, and C. Zou. The review also highlights the main topics and contributions of the selected papers, and proposes a research agenda for future work.
MEDICAL EFFECTS OF PRODUCTS OBTAINED FROM WILD ROSE PLANT
Authors: Çiçek Hülya , Kaya Hanim Seval , Kilic Cemile , Savas Muslum , Ravichandran Subramanian
Published: January 2023

Except for one tropical African species, the Rosa L. species (roses; Rosoideae: Rosaceae) has 150–200 species that are extensively dispersed throughout temperate and subtropical ecosystems of the northern hemisphere. The fact that Central Asia is the rose's native continent is underlined in numerous sources. A quarter of the rose species are found in Europe and North America, while nearly half are found in Asia.
Rosa damascene Mill is the species utilized to obtain rose oil, even though there are 24 types of roses registered in Turkey's flora. Rosa damascene, also referred to as the Damascus Rose, Pink Oil Rose, Oil Rose, and Isparta Rose Rose is a perennial, thorny, intensely perfumed, pink-hued, half-layered, and winter-hardy shrub that only blooms in the spring. The range of products is also increasing due to the demand for roses and rose products in this sector. Many products are being developed in the field of nutrition, cleaning, and cosmetics.
The aim of this study is to investigate the effects of wild rose plants in the field of health and to expand their use. However, it is thought that increasing the variety of products obtained from the wild rose plant may contribute to the country's economy.
The aim of the study is to investigate the use of wild rose plant in our country and in other countries, to show in which diseases it is used and to determine its contribution to the economy of the countries.
An overview of COVID 19 effects On Some human Body Function Bio Markers
Authors: Alfarga Ammar , Alkaraan Naif Saad , Afifi Mohamed , Morsy Nagy Abdallah
Published: January 2023

Despite the emergence of COVID 19  since 20019 and despite the many studies that researchers have raced to uncover the truth about this virus, there is still great ambiguity in everything related to this virus, especially its behavior inside the human body and the body’s reaction to it. The body reaction to COVID 19 differ greatly from one individual to anther in terms of its type and severity. Hence the importance of this review, as if we understand the changes that this virus causes in the human body and are able to measure its bioindicators, this gives us the ability to understand the behavior of this virus inside the body and thus enables us to overcome it. The investigation of different biomarkers induced by COVID 19 infection will open the dour to the researchers to understand the molecular mechanism of viral infection gives new diagnostic tools for the viral infection and gives the researcher a chance for discovering  new strategies for COVID 19 treatment and prevention, and invention of new pharmatheutical products for viral treatment.
Assessment of results of thoraco - laparoscopic esophagectomy
in patients receiving neoadjuvant chemoradiotherapy for esophageal cancers
Authors: Nguyen Xuan Hoa ,   Tong Quang Hieu, Pham Quang Thai, Pham Ba An, Pham Duc Huan, Do Mai Lam
Published: January 2023

Abstract
Introduction: Laparoscopic esophagectomy plays an important role in esophageal cancer. In recent years, the treatment of esophageal cancer is multidisciplinary, especially in neoadjuvant chemoradiotherapy for stages from IIB-IV to downstage to increase the possibility of R0 resection and survival. Globally, there have many studies showing the feasibility, safety, and effectiveness of laparoscopic esophagectomy after neoadjuvant chemoradiotherapy in patients with esophageal cancers. In Vietnam, there has been a paucity of data and surgical results in this group of patients. Therefore, we conducted a study to evaluate the safety, feasibility, and effectiveness of laparoscopic esophagectomy in patients receiving neoadjuvant chemoradiotherapy for esophageal cancers at Viet Duc Hospital.
Patients and methods: A retrospective study of patients who underwent the thoraco-laparoscopic esophagectomy receiving neoadjuvant chemoradiotherapy at Viet Duc hospital from T9/ 20217- T9/2021.
Results: From September 2017 to September 2021, there were 30 patients with esophageal cancer receiving neoadjuvant chemoradiotherapy followed by thoraco-laparoscopic esophagectomy. 100% were male, the mean age was 55.2 years old. Tumor locations in the middle and lower third parts were 53.3% and 46.7% respectively. 96.7% was squamous cell carcinoma, adenocarcinoma accounted for 3.3%. Before chemoradiotherapy stage III, and IV was 80%; 16.7%, after chemoradiotherapy, stages II and III were 43.3% and 40%. The average operation duration was 283 minutes, the average blood loss during video assisted thoracotomy was 60ml, there were no intraoperative complications, and there were no cases requiring conversion to open thoracotomy. The duration of intubation was 2.1 days, the average hospital stay was 12.5 days. There were 13.3% respiratory complications and 6.7% had experienced anastomosis leak. There were no postoperative deaths. The average number of harvested lymph nodes was 19, the lymph node metastasis rate was 43%. R0 resection rate was 93,4%. The results were 40% consistent completely with the histopathological examination. The mean survival time after surgery was 27 ± 3.7 (months), and the survival rate after 2 years was 42%.
Conclusions: Thoraco-laparoscopic esophagectomy after neoadjuvant chemoradiotherapy is a feasible, safe, and beneficial procedure for post-surgery recovery of patients.
Keywords: Esophagael cancer, Thoraco-laparoscopic esophagectomy, neoadjuvant chemoradiotherapy.
HOW THE NEGATIVE AFFECTIVE RELATION BETWEEN THE SCHOOL COMMUNITY HARMS THE LEARNING OF STUDENTS AT THE STATE SCHOOL PROFESSOR DONIZETTI APARECIDO LEITE
Authors: Rocumback Flose Keila , Conceição Bernucio Lourenço Pereira Patrícia , Monteiro Júnior Walfrido
Published: January 2023

This article addresses the topic: Affectivity and Learning and has as an investigation problem: how can negative affectivity affect student learning? The following research questions are: how does the affective relationship influence learning? How does the negative affectivity with the school community occur? What are the main problems of this school community in relation to affectivity? As a central assumption: negative affectivity impairs students’ learning. The research objectives are: to analyze whether the relationships between the school community are affective. To verify how the negative affective relationship between the school community influences the low levels of student learning. The qualitative and quantitative research was selected in the execution of this research and the case study as an investigation method with the application of a poll with the participation of professors, employees and students.
CONTEMPORARY LAW AND THE REGULATION OF THE DIGITAL ENVIRONMENT
Authors: Lima Gomes Alexandre , Christine de Castro Souza Urano Nadja
Published: January 2023

The article is a brief study on information technologies and the impacts on society and the science of law, specifically regarding the challenges of international law in the face of international data transfers and regulatory limits
Evaluación de una experiencia de flipped classroom
Authors: Escrig-Tena Ana Belén , Segarra-Ciprés Mercedes , García-Juan Beatriz , Salvador-Gómez Alejandro , Flor-Peris María Luisa , Alexandra Badoiu Georgina
Published: January 2023

Este trabajo ha obtenido un Accésit del Premio Estudios Financieros 2022 en la modalidad de Educación y Nuevas Tecnologías.
La flipped classroom es una metodología activa que cambia el modelo de enseñanza tradicional y genera una conexión emocional con el estudiantado (hombres y mujeres). El propósito de este estudio es analizar en qué medida la flipped classroom promueve el aprendizaje significativo del estudiantado y permite un aumento de su satisfacción y/o estrés en la docencia de la materia de Gestión de la Calidad en la Universitat Jaume I, utilizando el novedoso modelo de demandas y recursos en el estudio (DRE). La investigación concluye que la flipped classroom promueve el aprendizaje significativo. Si bien la percepción de carga de trabajo está relacionada con el nivel de estrés de los estudiantes, ni la carga de trabajo ni el nivel de estrés se traducen negativamente en términos de aprendizaje.
La influencia de las redes sociales como factor de riesgo en el desarrollo de la anorexia y la bulimia nerviosas durante la adolescencia
Authors: Villar del Saz Bedmar Marina , Baile Ayensa José Ignacio
Published: January 2023

Los trastornos de la conducta alimentaria (TCA), como la anorexia y la bulimia nerviosas, son un grave problema de salud mental, en aumento desde hace décadas, que afecta especialmente a mujeres en la adolescencia. Las variables más estudiadas asociadas a su aparición son los medios de comunicación y la publicidad. La aparición de internet, sobre todo de la Web 2.0, y el uso masivo de las redes sociales, ha desplazado a los medios de comunicación tradicionales y nos transporta hacia un nuevo escenario de factores de influencia en el desarrollo de los TCA.
La presente revisión sistemática trata de conocer el estado actual de las investigaciones que relacionan las redes sociales como factor influyente en el desarrollo de la anorexia y la bulimia nerviosas. Para ello se realizó una búsqueda y análisis de material bibliográfico disponible en indexadoras como Google Académico, Scielo, Redalyc y Dialnet, y se procedió al estudio de 20 artículos de carácter científico.
En el análisis de los artículos seleccionados parece encontrarse una relación entre el desarrollo de la anorexia y la bulimia nerviosas entre las mujeres y variables vinculadas con las redes sociales.
Con los datos encontrados se puede presuponer que las redes sociales han ocupado el espacio de los medios de comunicación tradicionales, por lo que han asumido su papel y perpetúan el problema de los estereotipos de belleza ya existentes, pero añadiéndole el factor social del que los anteriores carecían. También se concluyó que no es posible hablar de redes sociales, en general, puesto que estas son muy heterogéneas, siendo Facebook e Instagram las más relacionadas con la anorexia y la bulimia nerviosas.
MỘT SỐ BIỆN PHÁP NÂNG CAO CHIẾN LƯỢC HỌC TỪ VỰNG CHO SINH VIÊN KHÔNG CHUYÊN TIẾNG ANH
Authors: Vu Tuan
Published: January 2023

Trong quá trình học ngoại ngữ, từ vựng có thể xem là phần quan trọng nhất vì nó là phương tiện dùng để diễn đạt ý tưởng đồng thời đó cũng là cầu nối để phát triển các kỹ năng ngôn ngữ chính nghe, nói, đọc và viết. Tuy nhiên, việc dạy từ vựng chưa thực sự được chú trọng và quan tâm đúng mức trong quá trình giảng dạy. Với các phương pháp giảng dạy từ vựng truyền thống đó là phương pháp ngữ dịch, được sử dụng phổ biến trong các lớp học ngoại ngữ hiện nay. Bài viết sử dụng phương pháp phân tích tổng kết kinh nghiệm để hình thành cơ sở lý luận. Phương pháp điều tra thực tiễn sử dụng câu hỏi đóng An két 5 mức Likert được áp dụng để tìm hiểu thực trạng việc học từ vựng hiện tại của sinh viên không chuyên ngữ như thế nào. Căn cứ vào thực trạng hiện tại, bài viết đề xuất biện pháp nâng cao việc học từ vựng hiệu quả cho người học. Kết quả của nghiên cứu đóng góp cho giáo viên thêm thông tin tham khảo hữu ích về cách giảng dạy từ vựng cho sinh viên không chuyên. Sinh viên sẽ nắm rõ được thông tin cần thiết cho việc học và phát triển từ vựng của mình thông qua bài viết.
Analysis of Factors Related to the Performance of Health Workers at the Royal Prima Medan General Hospital in 2022
Authors: Teguh Kurniawan Dendy , Lestari Sri , Eliza Putri Lubis Yolanda
Published: January 2023

The performance of health workers at RSU Royal Prima is experiencing a fluctuating trend so that it is still not optimal in providing services to patients and organizational responsibilities. Factors that are suspected to be related to the performance of health workers are individual, psychological, and organizational variables. This study aims to analyze the factors related to the performance of health workers. This type of research is quantitative analytic using a cross sectional design. The research was conducted at RSU Royal Prima Medan. The research population was 651 people, while the sample was 100 people. Sampling by means of simple random sampling. Data were analyzed using univariate, bivariate with chi-square test, and multivariate with multiple logistic regression at 95% confidence level (=0.05). The results showed that the factors related to the performance of health workers at RSU Royal Prima Medan were abilities and skills (p=0.015), motivation (p=0.033), leadership (p=0.024), and rewards (p=0.044). Factors that were not related were age (p=1.000), gender (p=1.000), perception (p=0.240), attitude (p=0.163), and job design (p=0.464). The most dominant variable relates to the performance of health workers, namely leadership. Health workers who stated good leadership had the opportunity to have good performance 8.2 times higher than health workers who stated poor leadership. It is recommended that the management of RSU Royal Prima Medan conduct continuous performance assessments of health workers.
Plan comunicacional digital en el sector Cochapungo del emprendimiento de Balsa Totora en la Parroquia San Rafael, Otavalo, Imbabura, Ecuador
Authors: Rodas-Pérez Manuel Antonio , Vera-Banegas María Emilia , Arteaga-Medina Galo Danny , Pinos-Medrano Viviana Fabiola
Published: January 2023

En la actualidad los medios de comunicación han dado pasos agigantados en los avances tecnológicos y el proceso comercial no se detiene ante las exigencias del medio, así como el marketing tuvo sus etapas que fue de lo tradicional a la digital y en el campo de la comunicación, ahora no solo cuentan medios tradicionales, sí no los OTL (on the line), herramientas como redes sociales, blogs, canales de vídeo, servicios de streaming, sitios webs, son un reflejo de la realidad actual. En los dos últimos años los negocios tuvieron que adaptarse a las necesidades locales, pasando del campo físico a la venta por plataformas digitales y en muchos casos, sin conocimiento de herramientas on line, aprendiendo al paso. Plataformas como zoom, apps, redes sociales y WhatsApp, fueron salvavidas de negocios, los emprendimientos que se salvaron fueron los que estaban preparados en el manejo de herramientas digitales. A nivel nacional existen emprendimientos como el de balsa totora en Cochapungo, en Otavalo, donde comunidades indígenas demuestran sus habilidades y destrezas, no solo en el ámbito artesanal, también comercial, fabricando con materia prima insumos como sillas, canastos y hasta barcos, trabajando a favor de una comunidad, aprovechando el entorno, invitando al turismo, si bien ellos manejan bien el comercio, la comunicación digital les cuesta todavía, el presente plan de comunicación digital para el emprendimiento de la balsa de totora pretende influir y enseñar estrategias de comunicación para que desarrollen crecimiento, no sólo económico, sino impulsando a la marca, para que sea difundida por medios digitales y darse a conocer a nivel nacional e internacional.
Aplikasi Monitoring Persediaan Barang Berbasis Web Pada Koperasi Pegawai Logistik Dolog Semarang Menggunakan Barcode Reader
Authors: Jarot Dian  , Fujiama Diapoldo Silalahi
Published: January 2023

Stock reports on purchases and sales of a period. useful for helping employees to assess the amount of inequality in the flow of purchases, monitor stock / inventory of goods, and provide reports both purchase reports, sales reports, stock condition reports, and profit / profit reports to management to determine further business policies The process of recording transactions in a conventional or paper-based manner is identical with several weaknesses, namely easily damaged, difficult / long when looking for stored data, difficult / long when it comes to generating reports. These weaknesses can be corrected by implementing computer-based monitoring applications. If the monitoring application is planned/made properly, the computer-based information system is relatively safer. The model to be developed refers to the Research and Development (R&D) model from Borg and Gall and the tools used and the tools used to design the system are use case diagrams, sequence diagrams, activity diagrams, and class diagrams. while the implementation of making stock/inventory monitoring applications is done with PHP web-based programming and databases using MySQL. This application can help and get more accurate information about the stock data of goods that have run out.
Sistem Informasi Persediaan Dengan Metode Period Order Quantity Berbasis Multiuser Pada PT Terboyo
Authors: Sidik  , Nailin Nikhlis Nailin Nikhlis
Published: January 2023

Sistem persediaan merupakan salah satu fungsi manajerial yang sangat penting, karena mayoritas perusahaan melibatkan investasi besar pada aspek ini, demikian juga bagi PT Terboyo  yang banyak menggunakan persediaan dalam bidang perencanaan dan pengendalian produksinya.

Metode Period Order Quantitymerupakan metode yang dapat membantu proses pengendalian persediaan bahan baku. Metode ini menggunakan pendekatan pada konsep jumlah pemesanan ekonomis yang dipakai pada setiap periode  yang bersifat permintaan diskrit atau beragam. Perhitungan metode period order quantity (POQ) menggunakan dasar pemesanan ekonomis yang nantinya akan digunakan sebagai data pendukung untuk menghitung interval pemesanan yang optimal. Sehingga perusahaan dapat mengurangi beban biaya yang dikeluarkan dalam melakukan pemesanan.

Dilihat dari masalah tersebut , maka penulis perlu mendesain ulang atas sistem informasi stok barang dengan menggunakan sistem yang berbasis komputer, yaitu program Microsoft Visual Basic. Desain sistem menggunakan Qlient-Server yang terdiri atas desain input, desain sistem dan prosedur , serta desain output. Sistem baru ini diharapkan mampu mengatasi kelemahan sistem informasi yang digunakan sebelumnya..
Technical Note: Constraining the hydroxyl (OH) radical in the tropics with satellite observations of its drivers: First steps toward assessing the feasibility of a global observation strategy
Authors: Anderson Daniel C. , Duncan Bryan N. , Nicely Julie M. , Liu Junhua , Strode Sarah A. , Follette-Cook Melanie B.
Published: January 2023

Abstract. Despite its importance in controlling the abundance of methane (CH4) and a myriad of other tropospheric species, the hydroxyl radical (OH) is poorly constrained due to its large spatial heterogeneity and the inability to measure tropospheric OH with satellites. Here, we present a methodology to infer tropospheric column OH (TCOH) in the tropics over the open oceans using a combination of a machine learning model, output from a simulation of the GEOS model, and satellite observations. Our overall goals are to assess the feasibility of our methodology, to identify potential limitations, and to suggest areas of improvement in the current observational network. The methodology reproduces the variability of TCOH from independent 3D model output and of observations from the Atmospheric Tomography mission (ATom). While the methodology also reproduces the magnitude of the 3D model validation set, the accuracy of the magnitude when applied to observations is uncertain because current observations are insufficient to fully evaluate the machine learning model. Despite large uncertainties in some of the satellite retrievals necessary to infer OH, particularly for NO2 and HCHO, current satellite observations are of sufficient quality to apply the machine learning methodology, resulting in an error comparable to that of in situ OH observations. Finally, the methodology is not limited to a specific suite of satellite retrievals. Comparison of TCOH determined from two sets of retrievals does show, however, that systematic biases in NO2, resulting both from retrieval algorithm and instrumental differences, lead to relative biases in the calculated TCOH. Further evaluation of NO2 retrievals in the remote atmosphere is needed to determine their accuracy. With slight modifications, a similar methodology could likely be expanded to the extra-tropics and over land, with the benefits of increasing our understanding of the atmospheric oxidation capacity and, for instance, informing understanding of recent CH4 trends.
Numerical modeling of relative contribution of planetary waves to the atmospheric circulation
Authors: Koval Andrey V. , Toptunova Olga N. , Motsakov Maxim A. , Didenko Ksenia A. , Ermakova Tatiana S. , Gavrilov Nikolai M. , Rozanov Eugene V.
Published: January 2023

Abstract. Using the general circulation model of the middle and upper atmosphere (MUAM), a number of numerical scenarios were implemented to study the impact of individual planetary waves (PWs) on the global atmospheric circulation, including zonal wind, temperature, and residual meridional circulation. The calculations were performed for the winter conditions of the Northern Hemisphere (January–February). The contribution to the formation of the dynamic and temperature regimes of the middle and upper atmosphere made by equatorial Kelvin waves propagating to the east, as well as atmospheric normal modes with periods from 4 to 16 days is shown. In particular, it is demonstrated that the impact of a 5-day PW and an ultrafast Kelvin wave can change the speed of circulation flows by up to 5 % in the areas of their amplitude maxima. The presented research results are important for a deeper understanding of the mechanisms of large-scale atmospheric interactions. Despite the obviousness and simplicity of the problem, such work has not been carried out at the moment.