bluuebunny/crossref_metadata_2025 huggingface dataset:
Medication Dosing for Children With Overweight and Obesity
Authors: Matson Kelly L. , Horton Evan R. , Capino Amanda C.
Published: October 2024

Approximately 14.7 million US children aged 2 to 19 years are obese. This creates significant challenges to dosing medications that are primarily weight based (mg/kg) and in predicting pharmacokinetics parameters in pediatric patients. Obese individuals generally have a larger volume of distribution (Vd) for lipophilic medications. Conversely, the Vd of hydrophilic medications may be increased or decreased owing to increased lean body mass, blood volume, and decreased percentage of total body water. They may also experience decreased hepatic clearance secondary to fatty infiltrates of the liver. Hence, obesity may affect loading dose, dosage interval, plasma half-life, and time to reach steady-state concentration for various medications. Weight-based dosing is also a cause for potential medication errors. This position statement of the Pediatric Pharmacy Association recommends that weight-based dosing should be used in patients ages <18 years who weigh <40 kg; weight-based dosing should be used in patients ≥40 kg, unless the recommended adult dose for the specific indication is exceeded; clinicians should use pharmacokinetic analysis for adjusting medications in children diagnosed with overweight and obesity; and research efforts continue to evaluate dosing of medications in children diagnosed with overweight and obesity.
Breast cancer diagnosis and staging in Chile: A non-randomized survey-based study to assess frequency and delays
Authors: Campaña Carla , Oyarte Marcela , Cabieses Báltica , Obach Alexandra
Published: October 2024

Introduction Breast cancer progression involves physiological mechanisms such as metastasis. Delays in diagnosis and treatment increase the risk of mortality and are associated with barriers to healthcare access. In Chile, breast cancer is highly prevalent, and early diagnosis has improved, although disparities in the disease evolution persist. This study characterized diagnostic and staging tests, waiting times, and sociodemographic profiles to identify delays and inequities in care. Methods Survey study. Using a non-probabilistic sample, a questionnaire was applied in an encrypted platform with prior informed consent. The instrument collected data on requested tests, associated times, staging, and sociodemographic characteristics. These variables were analyzed using descriptive statistics, tests of association, confidence intervals, and comparison tests using bootstrapping. Results A sample of 263 persons was obtained. The most requested tests were biopsy (99.62%) and blood tests (80.23%). The median number of tests requested was six (Q1:4, Q3:8), with a mean of 5.87 (standard deviation: 2.24). No significant differences were observed in the percentage of persons from whom the total number of examinations were requested according to the studied variables. The day-hour-result intervals ranged from 1 to 365 days. The median day-hour-result of the biopsy was 15 days (Q1:10, Q3:30). People between 40 and 49 years old, non-residents of the capital city, belonging to income quintile I, with high school education, from the public health system, with late-stage diagnosis had higher median day-hour-result in biopsy. There was no significant difference in the number of requested tests according to staging (I and II, or III and IV). Conclusions Biopsy in Chile is the test of choice for diagnostic confirmation in breast cancer. Other tests are requested regardless of the diagnosis stage, contrary to the recommendations of clinical guidelines. Cancer prognosis is crucial, especially in countries with greater inequalities.
An Extensive Analysis of Liver Cirrhosis’s Genesis, Pathophysiology, Epidemiology, And Diagnosis
Authors:   Department pharmacology,College of pharmacy, University of The-Qar,The-Qar,64001, Iraq, H.Thejeel Sara , Jebur Assala Salam ,   University of Thi-Qar – College of Science
Published: October 2024

Portal hypertension and liver failure can arise as a result of liver cirrhosis, a chronic illness characterized by the fibrosis and renewal of nodules in the liver. A number of long-term conditions can lead to cirrhosis, a progressive disease. after a few years or perhaps decades. Liver cirrhosis is one public health concern. Metabolic syndrome, autoimmune diseases, storage diseases, drug use, alcohol consumption, viral hepatitis, and toxic chemicals are the usual causes. Cirrhosis is the fourteenth most prevalent cause of death in adults. placing ninth overall and fourth in Europe and the US. Because this condition is symptomatic and often remains undiagnosed in its early stages, its frequency is underestimated. It typically progresses to the decompensated stage at a rate of 5 to 7% annually. Here, we discuss the pathophysiology, epidemiology, diagnosis, and etiology of liver cirrhosis.
Devlet Arşivleri Başkanlığı Osmanlı Arşivi'ndeki Erken Dönem Defterlerde Geriye Dönük Ebru Kullanımı, Ebruların Tarihlendirilmesi ve Su Bazlı Ebrular
Authors: Babaoğlu Tevfik Alparslan
Published: October 2024

Bu çalışma ile Devlet Arşivleri Başkanlığı Osmanlı dönemi defterleri ile sınırlı olmak kaydıyla erken dönem Osmanlı ebru tekniği hakkında bir değerlendirme yapmak amaçlanmıştır. Bunun için, Devlet Arşivleri Başkanlığının Osmanlı dönemine ait tüm tasniflerinde, 1650 yılına kadar görüntüsüne erişilebilen defterler taranarak ebru kullanılmış defterler tespit edilmiştir. Tarama sırasında daha sonra ki bir tarihte yapılmış olmalarına rağmen geriye dönük kullanıldıkları belirlenen çok sayıda ebruyla karşılaşılmış, bu ebruların geriye dönük kullanıldıklarına ilişkin kanıtlar ortaya konmuştur. Aralarında Osmanlı Arşivindeki tarihlenebilen en eski ebru da dahil olmak üzere kıvamı artırılmaksızın doğrudan su üzerinde yapıldığı değerlendirilen birçok ebru tespit edilmiş, bu ebruların bulunduğu defterlerin bir envanteri oluşturularak özellikleri belirlenmiş ve yapımlarında kullanılan teknik ve ortaya çıkan sonuçlar açısından bir Japon kâğıt bezeme sanatı olan suminagashi ile kıyaslamaları yapılarak XVI. yüzyıl ve öncesinde kullanılan ebru tekniği hakkında bilinenler güncellenmiştir.
Wheat Rust Disease Detection Using Convolutional Neural Network
Authors:   Faculty of Emerging Technologies, Sri Sri University, Cuttack, Odisha, India., Nanda Ch Biswaranjan , Mohapatra Sudhir Kumar , Satpathy Rabi Narayan
Published: October 2024

Wheat is a vital crop globally, playing a crucial role in ensuring food security. Any damage to wheat crops, particularly from diseases like wheat rust, can exacerbate the global food crisis. Wheat rust, along with other crop diseases, poses a serious threat to agricultural sustainability and food supply. Technological approaches to detect crop health can significantly enhance disease prevention compared to traditional manual methods. This study focuses on detecting wheat rust diseases, specifically wheat leaf rust, stem rust, and yellow rust, all of which vary in their impact on crops. By employing image analysis of wheat plants, the research aims to accurately distinguish between healthy crops and those affected by rust diseases. The experiments consider multiple variables, such as learning rate, dropout, and train-test split ratio, reflecting a comprehensive research approach. The model achieved an impressive 99.64% accuracy in detecting wheat rust, highlighting its potential for early disease detection and prevention.
Těžba lesního porostu ovlivňuje fenotyp živočichů: případová studie fluktuující asymetrie u střevlíka Notiophilus rufipes (Coleoptera: Carabidae)
Authors: Stočes Dominik , Šipoš Jan
Published: October 2024

We compared the rate of variability in the size of different body parts among three different treatments created by forest management (i.e. clearing, pole-stage stand, ecotone) in the Podyji National Park (Czech Republic). In order to describe changes, we used bioindicative values of the Carabidae (Coleoptera) with the example of Notiophilus rufipes (Curtis, 1829). We conducted fluctuating asymmetry (FA) of ten important metrical traits (e.g. antennal segments, length and width of third palpomer of the labial palpus). We found that specimens have sex specific association to FA of second antennal segment. The interaction of sex and treatment negatively affects the distribution of FA in polestage stand. We revealed that males had higher level of FA in pole-stage stand than females. Ecotones are zones where individuals from diverse habitats interact. Model of FA, with set sex as random effect, have positive association to litter and negative association to Collembola. This research contributes to forest management strategies by demonstrating how human-induced interventions influence eco-evolutionary link between stress and disturbance. The research suggests that for forest management, forest openings in thermophilic oak stands could support phenotypic variation in rare epigeic species.
Genetická charakterizace tisu červeného (Taxus baccata L.) v širší oblasti Podyjí/Thayatal a na Svitavsku s vazbou na ochranářský management
Authors: Novotný Petr , Komárková Martina , Cvrčková Helena , Dostál Jaroslav , Máchová Pavlína , Ponikelský Jaroslav
Published: October 2024

The aim of the work is to determine the genetic diversity, genetic differentiation and genetic structure of subpopulations of the specially protected common yew in the area of South Moravian Podyjí (Czech Republic), Thayatal (Austria) and in the Svitavy region (Czech Republic) using DNA analyses (nSSR-nuclear Simple Sequence Repeats). The subjects of the analyses were yews of 1) natural occurrences in the territory of the Podyjí National Park (NP), 2) cultural origin in the Podyjí NP, 3) natural occurrences in the Thayatal NP (Austria), 4) natural occurrences outside the Podyjí NP, and 5) cultural origin in the Podyjí region outside the NP. For the comparison and better interpretation of results there also were analysed geographically more distant subpopulations, 6) natural occurrences in the Hřebečský ridge (NW Moravia), 7) cultural yew occurrences in the Svitavy region (NE Bohemia & NW Moravia), 8) natural occurrences in the Jílovské yews (N Bohemia), and 9) natural occurrences in the Moravian Karst (S Moravia). We observed higher level of genetic diversity (Ho = 0.54; He = 0.77), the FST with ENA correction ranged from 0.007 to 0.123. According to a STRUCTURE analysis, high genetic similarity was observed between samples from the Podyjí NP and Hřebečský ridge. The impact of the analysis results on the conservation management of tested populations was outlined.
My conflicted thoughts on the UK’s assisted dying bill
Authors: Eve Martin Paul
Published: October 2024

The UK currently has an assisted dying bill going through parliament and I am very conflicted about it. On the one hand, I am a member of DIGNITAS, the organization that supports assisted dying and that runs a “clinic” in Switzerland to which members who are terminally ill can travel to end their lives. I have no desire for the end of my life to be a mess of literally unbearable suffering and nausea, even with palliative care.
OERinfo-Erklärvideos (1/5): „Urheberrecht in der Bildung“ mit Paul Klimpel
Authors: Fischer Georg
Published: October 2024

Wie sind Urheber-, Nutzungs- und Leistungsschutzrecht eigentlich definiert? Wo liegt die Grenze zwischen öffentlicher und nicht-öffentlicher Nutzung? Und was bedeutet die „15%-Regel“ für nicht-kommerzielle Bildungseinrichtungen? Paul Klimpel liefert Antworten im Erklärvideo von OERinfo. Paul Klimpel und Till Kreutzer arbeiten als Anwälte bei iRights.Law und engagieren sich als Autoren bei iRights.info.
Privacy Preserving In IoT While Data Sharing Based On Blockchain
Authors: A Shabeena , DK Kalaivani
Published: October 2024

With the dramatically increasing deployment of intelligent devices, the Internet of Things (IoT) has attracted more attention and developed rapidly. It effectively collects and shares data from the surrounding environment to achieve better IoT services. For data sharing, the publish subscribe (PS) paradigm provides a loosely coupled and scalable communication model. However, due to the loosely coupled nature, it is vulnerable to many attacks, resulting in some security threats to the IoT system, but it cannot provide the basic security mechanisms such as authentication and confidentiality to ensure the data security. Thus, in order to protect the system security and users privacy this paper presents a secure blockchain based privacy preserving access control scheme for the PS system, which adopt the fully homomorphic encryption (FHE) to ensure the confidentiality of the publishing events and leverage the ledger to store the large volume of data events and access crossdomain information. Finally, analyze the correctness and security of our scheme; moreover, we deploy our proposed prototype system on two computers and evaluate its performance. The experimental results show that in PS system can efficiently achieve the equilibrium between the system cost and the security requirement.
Distribution System Protection with PV Plants Using Q-Axis Components
Authors: AP Akhil
Published: October 2024

Satisfying fault ride through requirements, solar photovoltaic (PV) plant remains connected to the grid even during a fault. With the current limiting feature, the plant current during a fault becomes comparable to its rated current. This imposes challenges to conventional local data based protection methods employed in the relay on PV side. In such a situation, the selectivity of a protection scheme is crucial for maintaining an uninterrupted supply to customers. In this article, a q axis component based protection scheme is proposed for the distribution system with a PV plant. The method extracts the second order harmonic components of q axis voltage and current at relaying points for fault detection and direction identification. Using this direction information at both ends of a line segment is protected, internal and external faults are discriminated. The performance of the proposed method is tested on a 14 bus distribution system for various fault cases. A comparative analysis with existing techniques shows the strength of the proposed method. Hardware in loop testing using OPAL RT simulator as a system and Arduino NANO microcontroller as relay validates the performance of the proposed method in real time.
The Effectiveness of Test for Speed and Strength Development for 12-14 Years Boys Judo Athletes: A Case Study of Binh Duong Province, Vietnam
Authors: Thuy Nguyen Thi Huong
Published: October 2024

Judo is an individual combat sport that requires high psychological, technical, tactical and physical factors, in which strength and speed play an important role. The aim of the study was selecting some tests for speed and strength development for 12-14 years boys Judo athletes, evaluating the effectiveness of these tests to develop speed strength for them. The study group consisted of 20 boys 12-14 years old Judo athletes in Binh Duong Province, Vietnam. The test for speed and strength development (collecting by previous research) was used in the study, including 5 tests: (1) Test 30m high start run (s); (2) Test long jump in place (cm); (3) Test prone push-up 15s (times); (4) Test Seoinage kick 20s (times); (5) Test knocking down Ippon Seoinage 30s (times). Test results based on the score tables were subjected to statistical calculations. An arithmetic mean, and Cv index were calculated for independent samples. The boys 12-14 years old Judo athletes who train 5 tests for speed and strength development exceed on the level statistically significant than the boys who practice current test. Comparing the results after the experiment between the two groups shows that the test system introduced by the study is superior to the current test system in terms of development rate (in each survey indicator, as well as in terms of average development rate).
Evaluation of Vietnamese Workbook 2 (Connecting Knowledge with Life)
Authors: Linh Truong Thi , Hong Nguyen Thi , Dao Dang Phan Quynh
Published: October 2024

Language is a tool of speech and thinking. Teaching Vietnamese in elementary school first teaches students the ability to use that tool fluently and effectively in study and life. To practice and use Vietnamese fluently, students must also practice regularly with exercise books – an effective support tool in teaching Vietnamese. However, not all teachers know how to effectively use Vietnamese Workbook 2 (Connecting Knowledge with Life) in supporting teaching work. Our article uses statistical and classification methods for some specific types of exercises in exercise books. Then use analysis and synthesis methods to solve the problem. This article evaluates the content and amount of knowledge in the book. Furthermore, the article offers solutions to overcome the limitations and enhance the positive aspects when using the book in the teaching and learning process of teachers and students in the Vietnamese subject 2 (book series Connecting Knowledge and Life).
Teachers’ Work-Life Balance and Well-Being Across Opol East District, Division of Misamis Oriental
Authors: Duran Erlyn P. , Pontillas Pepa V. , Comon Jovit D.
Published: October 2024

The study investigates the relationship between work-life balance and well-being among teachers in Opol East District, Misamis Oriental for the 2023-2024 school year, focusing on workplace support, work-family conflicts, and satisfaction. It involved 159 teachers selected through random sampling and used a descriptive-correlational design with an adapted questionnaire. The findings indicate a generally positive work-life balance, with satisfaction being closely linked to overall well-being. Emotional well-being was particularly strong, while work-family conflict mainly impacted mental well-being, and family-work conflict was significantly associated with social well-being. The study emphasizes the crucial role of workplace support in fostering teachers' well-being and suggests that targeted interventions are needed to manage specific conflicts. It concludes that enhancing work-life balance through supportive policies and a better working atmosphere can significantly improve teachers' well-being, satisfaction, and overall educational outcomes. Schools and educational institutions are encouraged to focus on creating environments that support teacher satisfaction and well-being, contributing to a stronger educational community.
Artista é artista até fritando ovo: mediações históricas, tecnológicas e sociais no mundo do trabalho da música
Authors: Requião Luciana , Ampáro Breno
Published: October 2024

Neste artigo buscamos discutir a configuração do trabalho musical na contemporaneidade, em especial de intérpretes e compositores/as. A investigação, a partir da problemática do músico multitarefas – aquele que concentra em sua atividade uma série de funções antes realizada por outros profissionais na cadeia produtiva – busca relacionar as dimensões de trabalho, informação, tecnologia e tempo. A partir de duas entrevistas realizadas à luz da literatura científica, pôde-se observar nuances históricas de um trabalho em plena transformação ou adaptação. As recorrentes reestruturações produtivas, catalisadas a partir dos anos 1970 em nível global, parecem ter incutido na forma do trabalho musical, uma aguda transformação nas formas de produzir, distribuir e comercializar música nos últimos 20 anos. As condições de trabalho no presente parecem inspirar um horizonte pouco favorável para aqueles que vivem de sua música, tal qual sugeriram as entrevistas.
As transformações e heranças do modelo pedagógico Napolitano: uma pequena reflexão a partir do tratado de João Sépe
Authors: Tavares Fernando , Machado Neto Diósnio
Published: October 2024

Este artigo explora a evolução do modelo pedagógico napolitano, concentrando-se nos trabalhos de Fedele Fenaroli (versões de 1775 e 1847) e João Sépe (lançado em 1942). Destaca como o livro “Regole musicali per i principianti di cembalo”, lançado por Fenaroli, testemunhou mudanças no pensamento musical ao longo do século XIX e possuía semelhanças com os exercícios de harmonia e contraponto, no “Tratado de Harmonia” de João Sépe, amplamente utilizado em escolas de música no Brasil. Para tanto, em um primeiro momento, comparamos o formato da escrita dos exercícios e discutimos o modelo de ensino por meio dos baixos instrucionais. Posteriormente, apresentamos um modelo comparativo dos quatro ensinamentos musicais fundamentais dos cadernos de partimento: Regra da Oitava, Cadências, Suspensões e Movimentos de Baixo. Ademais, apresentamos uma breve discussão sobre as formas de modulações que encontramos nos autores. Por fim, demonstramos como a realização harmônica, transmitida através dos baixos, ganha destaque, evidenciando a força do acorde como unidade harmônica em relação às passagens contrapontísticas.
Quantificação do grau de dissonância cromático como ferramenta de planejamento composicional: uma proposta pedagógica
Authors: Oliveira Liduino José Pitombeira de
Published: October 2024

O estudo da dimensão vertical ou harmônica da música envolve duas perspectivas fundamentais: a léxica e a sintática. No contexto léxico, lidamos com acordes, enquanto na perspectiva sintática, focamos nas relações entre esses acordes. Quando abordamos o léxico harmônico, encontramos duas dimensões fundamentais, uma de natureza quantitativa e outra qualitativa. A dimensão quantitativa diz respeito à contagem das notas que compõem os acordes, ou seja, sua cardinalidade. Enquanto isso, no âmbito qualitativo, adotamos a expressão “grau de dissonância” para descrever essa característica. Na primeira parte deste estudo, vamos explorar a construção de um léxico harmônico com acordes contendo três notas, usando combinações dos intervalos entre as diferentes notas da escala cromática. Na segunda parte, iremos analisar diversos fatores de natureza sintática, incluindo a tonalidade, a parcimônia, o grau de dissonância, aspectos estocásticos e o conceito de intertextualidade na música.
Apontamentos para uma teoria da forma em música popular
Authors: Almada Carlos de Lemos
Published: October 2024

Este artigo integra uma pesquisa abrangente sobre a estrutura da Música Popular Brasileira (MPB), focando em aspectos da forma. O estudo, que pretende essencialmente estabelecer uma base sólida para uma teoria sobre forma em música popular, é motivado pela escassa literatura específica sobre o assunto e toma como principais referenciais para suas formulações conceitos e pressupostos derivados da assim chamada Neue Formenlehre. Iniciando com um grupo de definições básicas (forma nominal, camadas e níveis estruturas, relações S/C e fatores de segmentação), o estudo propõe tipologias referentes às ideias de macro e microformas, concentrando-se especialmente neste último aspecto, ao qual se associa a dualidade conceitual período e sentença (SCHOENBERG, 1967; CAPLIN, 1998). Como ponto central de discussão, propomos uma perspectiva mais flexível para ambos os conceitos, a partir da observação da prática musical no contexto da MPB. A construção de um modelo analítico voltado para as formulações propostas e sua aplicação em quatro estudos de caso são contemplados nas seções finais do artigo.
Ensinar música na educação básica: a compreensão da função da docência na perspectiva de um estagiário de um curso de licenciatura em música
Authors: Joaquim Danielle Chaves , Del-Ben Luciana
Published: October 2024

Este artigo tem como objetivo investigar como o estagiário do curso de licenciatura em música constrói compreensões sobre a função de ensinar música na educação básica. Fundamentando-se nos estudos de Maria do Céu Roldão sobre profissionalidade docente, foi desenvolvido por meio de análise documental, tendo como material empírico o portfólio de estágio de um licenciando em música, composto por oito relatórios. Os resultados indicam que a compreensão do estagiário se constrói ao longo do tempo, a partir de encontros no campo de estágio, com alunos, professoras e escola, do encontro consigo mesmo e dos encontros coletivos de orientação na universidade. Quanto mais encontros no campo de estágio, maior a possibilidade de construir entendimentos mais amplos, mas as transformações da compreensão do estagiário dependem da ampliação de saberes e do acionamento de geradores de especificidade do conhecimento docente, conduzidos pela orientação. É, portanto, a partir da interação entre o espaço de atuação profissional e a universidade que a função de ensinar música na educação básica vai sendo compreendida em sua complexidade.
Drop Bothsideism
Authors: Wind Marlene
Published: October 2024

Western media are not equipped to handle right-wing populists like Donald Trump, Orbán, or the AfD. Moreover, constitutional theorists who argue that democracy should be purely procedural are joining the populist chorus. In our current age of populism we keep telling ourselves that everyone’s voice is always equally valid – also when based on lies and disinformation. It’s just another “point of view”. What populism has undermined is the right but also the courage to call out those who deliberately spread lies as well as those who in doing so openly use democratic institutions to destroy democracy.
Racial disparity in PM2.5 species and DNA methylation in CARDIA: An epigenome-wide association study
Authors: Yao Jie , Zheng Yinan , Shen Jincheng , Joyce Brian T , Hao Ke , Shah Ravi V , Murthy Venkatesh L , Sidney Stephen , Lloyd-Jones Donald , Hou Lifang , Zhang Kai
Published: October 2024

Minorities experience a disproportionate impact from PM2.5 pollution, and biological mechanisms remain unclear. No studies have examined the epigenome-wide association between DNA methylation level and PM2.5 species using longitudinal measurements of methylation among Blacks. This study aims to evaluate the relationship between exposure to PM2.5 species and DNA methylation as well as assess possible race-specific effects. Genome-wide DNA methylation levels were profiled on 1,081 longitudinally followed participants (432 Black and 649 White adults) using the Infinium MethylationEPIC array. We examined the association between one-year average PM2.5 species (black carbon, ammonium, nitrate, organic matter, sulfate, soil, and sea salt) exposure prior to exam year (Y)15 (2000-2001) and methylation at 841,639 CpG sites at Y15 and Y20 (2005-2006), respectively. In the association analysis of PM2.5 species at Y15 with DNA methylation at Y20, methylation in 17 and 2 CpG sites, respectively, was significantly associated with nitrate and ammonium exposure. The magnitudes of coefficients of these significant CpG sites at Y20 increased by 2- to 48-fold compared to the cross-sectional association analysis of PM2.5 species exposure prior to Y15 and DNA methylation at Y15. Black participants had stronger associations than White participants. Gene enrichment analysis indicated gene targets might be relevant to pathways including basal cancers, platelet activation, signaling, and aggregation. This study represents the first one to investigate the association between PM2.5 species exposure and DNA methylation among Black and White adults using longitudinal measurement, highlighting the significance of considering race-specific epigenetic regulation in relation to air pollution-related health issues.
The Influence of Logistics Activity on Sustainable Performance of Air Cargo Business in Thailand
Authors: Hongsakul Bharis , Chuaychoo Ichayaporn
Published: October 2024

This research applies logistics management concepts to sustainable business operations in the context of air cargo businesses in Thailand. The study aims to understand how logistics activities impact the sustainable performance of air cargo businesses. The objectives of this study were to examine: 1) logistics activities in air cargo businesses in Thailand, and 2) the influence of logistics activities on the sustainable performance of the air cargo business. This study consists of descriptive research, utilzing a questionnaire for data collection. The sample consisted of 424 employees of air cargo businesses operating in Thailand. The findings reveal that all 9 logistics activities significantly influenced the sustainable performance of air cargo businesses in Thailand, in terms of economic, social, and environmental performance, where Customer Services and Support (CSS) had the highest average value with a mean value of 5.90  (S.D. = 0.723).
Regarding the results of the study of influences, Facilities Site Selection, Warehousing, and Storage (FWS) was found to strongly impact Economic Performance (ECOP) with a β value of .740. Meanwhile, Reverse Logistics (RL) had the greatest impact on Social Performance (SOCP) with a β value of 0.843, and Transportation (TRAN) had the greatest influence on Environmental Performance (ENVP), with a β value of 0.749.
The findings can support the introduction of business guidelines to enhance competitiveness and enable the achievement of sustainable success, offering encouragement for Thailand as a key air cargo hub for Southeast Asia. Moreover, the study can be used to enhance academic knowledge in the field of logistics and contribute to the future sustainable performance of the air cargo business.
Strategic Execution Drivers on Performance of Private Hospitals in Nairobi City County, Kenya.
Authors: Mola Nancy Mating’i , Sije Antony , Mangana Robert
Published: October 2024

This study assess  the influence of strategic execution drivers, specifically strategic leadership and resource allocation, on the performance of private hospitals in Nairobi County, Kenya. Strategy formulation often succeeds, but execution presents significant challenges, particularly in converting plans into successful outcomes. The research highlights the critical role of strategic leadership in shaping organizational culture, decision-making, and employee engagement, while resource allocation directly impacts hospitals' capacity to deliver quality healthcare and achieve operational efficiency. As Nairobi’s healthcare sector grows and competition intensifies, private hospitals must excel in strategy execution to maintain competitiveness. Despite their focus on clinical care, many hospitals face gaps in implementing strategic management, leading to performance deficiencies. Using Transformational Leadership Theory and the Resource-Based View (RBV) theory, the study explores how effective leadership and resource management drive operational success. The research employed a descriptive design, targeting key decision-makers across 62 private hospitals. Results from the analysis indicate that both strategic leadership and resource allocation play a significant role in shaping hospital performance, with correlations of 0.70 and 0.80, respectively. Findings suggest that private hospitals in Nairobi must prioritize aligning leadership and resource strategies to improve performance, meet operational goals, and enhance patient outcomes in an increasingly competitive environment
Calculating of Month and Day of Birth Ahead of The Wedding Day in The Javanese Culture: Perspective of Maqashid Al-Syari’ah
Authors: Mas'ud
Published: October 2024

Background. Counting the month and day of birth is  ritual; respect for traditions and beliefs that have existed for a long time in society; considered as one way to ensure that the couple starts their new life well and receives blessings from God.
Aim. Examines the role of Javanese culture in calculating the month and day of birth in relation to the upcoming wedding, as well as its relevance from the perspective of maqashid al-shari’ah.
Method. Qualitative approach involving in-depth interviews and participatory observation. Thematic analysis was employed to identify key themes of data and to connect with the theory of maqashid al-shari’ah.
Results. The practice carries values aligned with maqashid al-shari’ah, such as the protection of offspring and the formation of harmonious family relationship; provides spiritual and social reinforcement for the Javanese community; fostering mutual respect and strengthening the bonds between individuals and their traditions and beliefs.
FEATURES OF FIRST AID AND PSYCHOLOGICAL SUPPORT FOR CHILDREN IN EMERGENCY AND EMERGENCY SITUATIONS
Authors: Peshakova Varvara , Greshnyh Antonina
Published: October 2024

The issue of interaction of employees of EMERCOM of Russia with children is highlighted. The activities and measures contributing to maximizing the effectiveness of emergency rescue, evacuation, and rescue operations involving children are presented.
Revealing the issue of national security of the country, we touch upon the description of the protection of the population and territories from emergency situations. Protection is provided by the availability of highly qualified specialists. Special attention is paid to such components as: knowledge of child psychology, physical fitness, personal qualities (responsibility, endurance, sociability, observation), stress resistance. The rationale for the measures of a careful algorithm of work when working with children is as follows: in the event of an emergency, it is necessary to act decisively and quickly, and at the same time carefully and thoughtfully.
TITLED FIREFIGHTERS OF RUSSIA: CREATOR OF FIRST PROFESSIONAL FIRE PROTECTION OF RUSSIA (Prince Kochubey Viktor Pavlovich)
Authors: Vinogradov Vladimir , Greshnyh Antonina , Lugovoy Alexander
Published: October 2024

A brief pedigree and biography of prince Kochubey Viktor Pavlovich is given. His role in the creation and improvement of the structure of the police and professional fire protection of Russia as the first minister of internal affairs of the Russian Empire (1802–1807, 1819–1823) is shown. The activities of prince Kochubey Viktor Pavlovich in other government positions for the benefit of the Fatherland are briefly described.
RESEARCH OF SOCIAL INTELLIGENCE OF CADETS AND POSTGRADUATE STUDENTS AT THE SAINT-PETERSBURG UNIVERSITY OF STATE FIRE SERVICE OF EMERCOM OF RUSSIA
Authors: Mikhailov Valery , Mikhailova Valentina , Tukmacheva Marina
Published: October 2024

The features of the manifestation of social intelligence of adjuncts and cadets during their studies at the Saint-Petersburg university of State fire service of EMERCOM of Russia are considered. The ability to understand the behavior, actions of students, their logic and adequacy, interrelationships and interdependence of social contacts was evaluated. The main means of solving the task set for the authors was the methodology of Joy P. Guilford, designed to help assess the level of social intelligence of two categories of university students – adjuncts and cadets. The authors managed to carry out a comparative analysis of the behavior of employees, their ability to recognize different meanings of phrases, understanding the logic of the emergence and development of socio-psychological contradictions and reactions to nonverbal expression. The specific features of the ways of expressing the sense of «WE» are associated with the aggravation of the processes of group identification and reference are indicated. The practical significance of the results obtained for cadets, adjuncts studying at the Faculty of training highly qualified personnel, scientific and pedagogical staff and heads of structural divisions of EMERCOM of Russia is substantiated.
Percepción de la calidad del proceso de enseñanza-aprendizaje en las dimensiones de planificación, ejecución, evaluación en estudiantes de posgrado de la Universidad Emiliano Zapata
Authors: Ayala García Héctor Arturo , Ramírez Vázquez Ileana Aidee , Flores Godínez Vicente
Published: October 2024

En la Universidad Emiliano Zapata,  “tiene como política garantizar una enseñanza que destaque por el nivel académico y oportunidades para todos” (Universidad Emiliano Zapata, 2024). De manera que se analizaron la calidad del aprendizaje-enseñanza en las dimensiones de Planificación, ejecución, evaluación (Melgarejo Solís, Gianina, & Rivas Díaz, Luisa Hortensia, 2021), expectativas académica y laboral en estudiantes de posgrado de ingeniería, aplicándose a 37 estudiantes,  23 de las Maestría Ingeniería Industrial en Sistemas (65% masculino y 34% femenino) y 14 de la Maestría en Gestión y Administración, 72% femenino y 28% masculino; obteniendo que 32 alumnos son originarios del Estado de Nuevo León y 5 foráneos, residentes en 7 municipios de la metrópoli regiomontana, siendo 18 del sexo femenino y 19 masculino, mostrando cierta equidad de género, en edad se reconocieron 4 grupos; 15 alumnos de 20-29 años; 12 de 30-39 años; 8 de 40-49 años y 2 de 50-59 años, se identificó en la dimensión de Calidad, Muy de acuerdo 65.2%, De acuerdo 31.8%, Ni de acuerdo ni en desacuerdo 2.8% y En desacuerdo 0.2%; en expectativa académica, Muy de acuerdo 62.2%, De acuerdo 35.1% y Ni de cuerdo ni en desacuerdo 2.7%; en expectativa laboral, Muy de acuerdo 62.2%, De acuerdo 35.1% y Ni de acuerdo ni en desacuerdo 2.7%.
Mathematical Model for Optimal Location of Cellular Transmission Towers
Authors: Ruiz Gomes Cristiane , Ruiz Gomes Igor , Simões Gomes Herminio
Published: October 2024

This paper applies a mathematical model for the optimal location of cellular signal transmission towers in a scenario different from the original scenario for which the model was developed. The proposed optimization aims to maximize the number of users served while maintaining a minimum signal quality standard. To validate the model, measurement campaigns were carried out at 44 points in a residential setting in the municipality of Castanhal-PA, at frequencies of 1800 MHz and 2600 MHz. The model outputs provide the received power, the average loss and the optimal location of the new tower to be installed.
Desarrollo de Competencias Digitales para los Estudiantes de Bachillerato de la Ciudad de Otavalo, provincia de Imbabura – Ecuador
Authors: Pavón Anrango Juan Carlos , Cajo Guallasamín Vanesa Estefanía
Published: October 2024

El presente artículo aborda el estudio sobre las competencias digitales de los estudiantes de bachillerato de la ciudad de Otavalo, provincia de Imbabura – Ecuador. Considerando el uso de las nuevas plataformas digitales en la educación, el presente proyecto de investigación tiene como objetivo analizar las competencias digitales que el estudiante tiene con el uso de la plataforma Suite de Google, conjunto de herramientas ofimáticas que sirven para mejorar de trabajo colectivo, grupal o individual. Su enfoque fue descriptivo, por que nos permitio describir, explicar, analizar, y comparar las características de una población o situación en particular; transversal por que se recopilo  la información de una población de 384 estudiantes de 5 unidades educativas mediante un formulario de Google Forms en el periodo de agosto 2022 a junio 2023, y cuantitativo con un diseño metodológico no experimental, por que se basó especialmente en la observación de los hechos exactamente como suceden en su contexto natural. Con esta investigación se pudo observar que los estudiantes hacen un énfasis en mejorar de sus competencias digitales con un 95%%, de deseo de aprender y un 5% que no tienen interes en desarrollar mayor destrezas que las que ya tienen.
Study of Co-relation between Clinical and Diagnostic Profile of Pediatric Tuberculosis in a Tertiary Care Hospital
Authors: Singla Deepanshu , Agrawal Manish , Ranjan Amritesh
Published: October 2024

Objective: Study of Co-relation between Clinical and Diagnostic profile of Pediatric Tuberculosis in a tertiary care hospital. Methods: This hospital-based observational study was conducted at the Department of Pediatrics, Muzaffarnagar Medical College and Hospital, covering a population of children aged <18 years diagnosed with TB. Data collection spanned 18 months, with a sample size of 100 children. Results: The study identified a predominant TB incidence in children aged 11-17 years (73%) with more females affected (66%) than males. Common symptoms included fever, cough, weight loss, and loss of appetite. Diagnostic findings showed a high use of Chest X-rays and Molecular tests. PTB was the most common form, accounting for 47 cases, EPTB accounting for 48 cases and Disseminated form was seen in 5 cases. Conclusions: Chest X-ray, Tuberculin Skin Test, Molecular Tests, and Blood Tests were universally performed on all patients. Microbiological confirmation is more common in pulmonary tuberculosis cases, while radiology, FNAC/Biopsy, and body fluid analysis are more utilized for extrapulmonary/disseminated cases. Diagnosing tuberculosis (TB) in children is often challenging due to several factors, including the difficulty in obtaining specimens and the typical paucibacillary nature.
Borderline Lepromatous Leprosy Masquerading as Granuloma Annulare: A Case Report
Authors: B Birundha , Kumaran Senthil , S Kalaiarasan , Shambavi Jeya , R Jawahar
Published: October 2024

Background: Leprosy is a chronic granulomatous disease caused by Mycobacterium Leprae. Leprosy is a great imitator with its various atypical, unusual and varying clinical presentations which can be confused with many infectious and non-infectious diseases. Case Report: A 46-year-old female presented to the dermatology department with complaints of painful raised lesions over face, upper back, upper limbs, lower legs and feet for 12 months. Clinically suspected as a case of Granuloma annulare. Punch biopsy was taken which revealed epidermis with dermis showing nodules of histiocytes and lymphocytes with grenz zone at the dermoepidermal junction. Acid fast stain and Fite Faraco stain was performed which revealed the presence of leprae bacilli with bacteriological index of 4+. Conclusion: Detailed history taking and correlating clinical picture with morphology is required to diagnose atypical presentations of leprosy. Early diagnosis helps to provide appropriate treatment and thus prevent from devastating complications.
Neuropeptide Y: an undisputed central simulator of avian appetite
Authors: Mahdavi Kimia , Zendehdel Morteza , Zarei Hamed Zarei
Published: October 2024

During the last few decades, identifying the physiological pathways involved in appetite regulation has become popular among researchers. Although studying feeding regulation in birds, especially in poultries (for breeding purposes) and ornamental birds (for therapeutic purposes), is extremely important, limited experiments have been conducted on these animal models. Until today, more than fifty neurotransmitters affecting birds' appetite have been identified. In the current study, we overviewed the role of one of the most important neural mediators, neuropeptide Y (NPY), in regulating avian appetite. Based on the findings, the presence of this neuropeptide and its receptors in the key areas of food intake regulation, especially the arcuate nucleus (ARC) of the hypothalamus, has been proven. Numerous studies on birds have repeatedly shown the hyperphagic effects of NPY. Among the different NPY receptors, type 1, 2 and 5 receptors play the most important role in appetite regulation. It has also been observed that the interaction of NPY with neurotransmitters such as glucagon-like peptide-1 (GLP-1), vasotocin, bombesin, opioids, alpha-melanocyte-stimulating hormone (α-MSH), cocaine- and amphetamine-regulated transcript (CART) and gamma aminobutyric acid (GABA) is effective in NPY-induced hyperphagia. In addition, the NPY system is also involved in the effects of various mediators such as adiponectin, neuropeptide W (NPW), phoenixin-14, visfatin, adrenomedullin, spexin, kisspeptin, insulin, and somatostatin on appetite regulation. Finally, NPY seems to be one of the most important appetite-stimulating factors in birds and also plays an undeniable role in the effects of other neurotransmitters on appetite regulation.
The effect of brain-derived neurotrophic factor (BDNF) on food consumption of broilers: Role of serotonergic receptors
Authors: Zarei Hamed , Akhlaghi Hediye , Zendehdel Morteza
Published: October 2024

Previously, the effects of brain-derived neurotrophic factor (BDNF) on feed intake of mammals were studied, however, its role in avian feeding regulation remains unclear. Therefore, the present study aimed to investigate the possible effects of BDNF on the food consumption of broilers and its interaction with the serotonergic system. In the first treatment, broilers received intracerebroventricular (ICV) infusion of BDNF (7.5, 15, and 30 μg). BDNF (30 μg), Fluoxetine (10 μg), a serotonin reuptake inhibitor, and BDNF + Fluoxetine were injected in the second treatment. In subsequent treatments, instead of Fluoxetine, PCPA (serotonin synthesis inhibitor, 1.25 μg), SB242084 (antagonist of 5-HT2C receptor, 1.5 µg), and 8-OH-DPAT (agonist of 5-HT1A receptor, 15.25 nmol) were applied. Then, total food intake was recorded for 2 hours. According to the results, BDNF injection (15 and 30 μg) caused a significant decrease in the food intake of broilers compared to the control group (P<0.05). Simultaneous administration of PCPA and SB242084 with BDNF suppressed BDNF-induced hypophagia (P<0.05), while the injection of fluoxetine + BDNF strengthened this hypophagic effect (P<0.05). The decrease in feed intake caused by BDNF was not significantly changed by simultaneous injection of BDNF + 8-OH-DPAT (P≥0.05). According to the findings, it seems that BDNF reduces food consumption in broilers and this effect is probably mediated via 5-HT2c receptors.
Comparative histopathology of three Serotypes of live infectious bronchitis vaccine (IB88 – 4/91 – H120) in broiler chickens
Authors: Barari Mohammad , Khorrami Shima Khorrami , Mortazavi Seyyed Pejman , Bahonar Alireza , Charkhkar Saeed
Published: October 2024

Infectious bronchitis in birds, caused by a coronavirus, is a highly contagious viral disease that causes economic losses in the poultry industry worldwide. It affects the respiratory, urinary, and genital tracts, and control and prevention are focused on vaccination and biosecurity measures. This study compares histopathological lesions caused by IB88, H120, and IB4-91 vaccines in broiler chickens aged 1 to 5 days. One hundred Ross 308 chickens were divided into four groups: group 1 received the IB4-91 vaccine, group 2 was administered the H120 vaccine, group 3 received the IB88 vaccine, and group 4 served as the control group. Over a period of five days, starting from the second day, five chickens from each group were randomly selected and euthanized. Histopathological samples were collected from the trachea, lungs, and kidneys, processed into slides, and examined under an optical microscope for comparative analysis. When comparing the control and vaccinated groups, there were significant differences regarding histopathological indicators. These included hyperemia and infiltration of inflammatory cells in the kidney, lung hyperemia, infiltration of inflammatory cells, necrosis of respiratory epithelium, and hyperplasia of tracheal mucous cells. Differences were noted between the IB4-91 and H120 groups regarding inflammatory cell infiltration, respiratory epithelium necrosis, tracheal mucous cell hyperplasia, and renal hyperemia. Similarly, variations were observed between the IB88 and H120 groups regarding respiratory epithelium necrosis and tracheal inflammatory cell infiltration. Furthermore, differences were identified in tracheal mucosal hyperplasia and renal hyperemia between the IB4-91 and IB88 groups. These findings highlight distinct histopathological responses induced by different vaccines in broiler chickens and emphasize the importance of vaccine selection in poultry health management.