bluuebunny/crossref_metadata_2025 huggingface dataset:
Open-angle glaucoma in diabetic patients’ prevalence and risk factors: a cross-sectional study in Sudan
Authors: Salih Omyma Abbas Banaga , Hamed Ehab
Published: May 2020

Background: Diabetic patients are at increased risk of glaucoma compared to the general population. Risk factors for glaucoma that is specific to diabetic patients include increased IOP, retinopathy and neovascular changes and years since diagnosis of diabetes. This cross-sectional study aims to report on the prevalence of glaucoma in diabetic patients in community diabetes centre in Sudan and examine associations with previously reported risk factors.Methods: A cross-sectional study was carried out in Omdurman specialised diabetic healthcare centre in Sudan. A total of 300 patients consented to participation. All patients filled in a survey for both demographics and diabetic disease history then had an assessment for glaucoma by an ophthalmologist. The assessment included examination of the anterior segment, optic nerve assessment and fundus examination using a stereoscopic slit lamp, intraocular pressure (IOP) measurement using tonometry, peripheral anterior chamber configuration and depth assessments using gonioscopy and central visual field assessment using perimetry.Results: Prevalence of open-angle glaucoma diagnosis was 2.8% among diabetic patients who were included in this study. Family history for glaucoma was significantly associated with increased risk of open-angle glaucoma (OR 5.67, 95% CI 1.74-18.45). Retinopathy was also associated with an increased risk of developing the condition (OR 3.1, 95% CI 1.11-8.51). Gender, years since diabetes diagnosis and medications did not have significant associations.Conclusions: Patients with diabetes are at increased risk of developing open-angle glaucoma, but the prevalence among the diabetic population attending community diabetes centre in Sudan remains low. Among different clinical determinants, diabetic retinopathy and genetic determinants may explain the increased risk in the diabetic population.
Comparative analysis of postpartum IUDC versus interval IUCD insertion: a study conducted in a tertiary care hospital in Karachi, Pakistan
Authors: Bano Zakia , Memon Sanober , Khan Fiza Ali , Shahani Mala Jitendra , Naz Urooj , Ali Syed Naqeeb
Published: May 2020

Background: To compare the effectiveness of postpartum intrauterine contraceptive device (PPIUCD) with interval IUCD in terms of effectiveness, expulsions, bleeding pain and other complications at Tertiary care Hospital.Methods: Current study was conducted among 224 women, at Gynaecology and Obstetrics of Reproductive Health Services-A (RHS-A) Centre of Jinnah Post Graduate Medical center, Karachi, for a period of Six months. Approval from Ethical committee and informed consent was taken from women and her husband before starting the study. The WHO medical eligibility criteria for contraceptive use (MEC) were followed and IUCD was inserted in 112 women in PPIUCD group and in 112 women in interval IUCD group. These cases were followed at 15 days, 6 weeks and 6 months. Results of PPIUCD group were compared with interval IUCDs group. Data was analyzed by using SPSS version 18.0. Continuous variables like age, parity, hemoglobin level were analyzed as mean±standard deviation. Frequencies and percentages were calculated for infection, expulsion, bleeding per vagina and effectiveness. Chi-square was applied to assess the difference between the categories. p value <0.05 was taken as significant.Results: The two groups were identical in mean ± SD age, parity, residence and baseline hemoglobin level. PPIUCD (Group-A) was more effective i.e., 87.5% as compared to interval IUCD (Group-B) i.e., 83.9%. Pain, PID, bleeding and expulsion of IUCD were more prevalent with interval IUCD (Group-B) than PPIUCD (Group-A) patients. Stratified analysis showed that age, parity & mean baseline hemoglobin were non-significant effect modifiers on the effectiveness among the two groups.Conclusions: Postpartum IUCD use was found to be a safe, simple, inexpensive and reversible procedure with higher chances of retention for a longer period. Additionally, there is decreased risk of complications and lower expulsion rates when compared with interval IUCD.
Different types of mucormycosis: case series
Authors: Jaju Madhusudan R. , Sagar R. Vidya , Srivastav Shashank Kumar , Singh Ranbeer , Kumar K. Vijay , Faisal Mohammed
Published: May 2020

Mucormycosis is the third invasive mycosis in order of importance after candidiasis and aspergillosis and is caused by fungi of the class Zygomycetes. The most important species causing Mucormycosis is Rhizopus arrhizus (oryzae). Identification of the agents responsible for mucormycosis is based on macroscopic and microscopic morphological criteria, carbohydrate assimilation and the maximum temperature compatible with its growth. The incidence of mucormycosis is approximately 1.7 cases per 1000 000 inhabitants per year. Clinical diagnosis of mucormycosis is difficult, and is often made at a late stage of the disease or post-mortem. We present here a series of five cases of different types of mucormycosis that were reported in our hospital till date. Of which three patients had good recovery and other two had a fatal outcome. Treatment of mucormycosis requires a rapid diagnosis, correction of predisposing factors, surgical resection or debridement as part of source control-and appropriate anti-fungal therapy. Liposomal amphotericin B is the drug of choice for this condition. The overall rate of mortality of mucormycosis is approximately 40%.
Histopathological spectrum of disorders of sexual development: a case series of seven cases
Authors: Bolde Saroj Ashok , Pirosha Arva Ali , Ramraje Sushma N. , Agale Shubhangi V.
Published: May 2020

Disorders of sexual development (DSD) refer to cases in which there is a discordance among at least two of the following; genetic sex, gonadal sex, genital tract sex and phenotypic sex. DSDs are quite rare with reported incidence varying from 1 in 4,500 to 1 in 5,500. Ovotesticular disorder is amongst the rarest variety of DSD comprising only to 3-10% of all cases of DSD with only 500 cases reported till now worldwide. Frequency of MRKH syndrome is 1 in 4,500 cases and is the cause of amenorrhoea in 15% of cases of primary amenorrhoea. Authors present a case series of seven cases of DSDs with three cases diagnosed as androgen insensitivity syndrome, two cases of true ovotesticular DSD (true hermaphrodite), one case each of mixed gonadal dysgenesis and Mayer-Rokitansky-Kuster Hauser (MRKH) syndrome. Authors received the histopathology specimen of these cases in this department which was extensively sampled to study the gonads and the other derivatives of Mullerian and Wolffian duct and to rule out presence of any malignancy.
DETERMINAN NON-PERFORMING FINANCING PADA BANK UMUM SYARIAH DI INDONESIA
Authors: Indrajaya Indrajaya
Published: May 2020

The accumulation of non performing financing in economic activities financed by banks can cause problems with the continuity of the bank's operations, if that exceeds certain limits will have potential to stop the bank's activities. This study aims to analyze the influence of bank’s internal variables like  FDR, CAR, BOPO and bank external variables like macroeconomic indicators consisting of exchange rates, inflation and GDP (GDP) against non-Performing Financing (NPF) of Islamic Commercial Banks in Indonesia. The data used are monthly industrial time series of Sharia Commercial Banks (BUS) for the period June 2014 to December 2018 sourced from the Islamic Banking Statistics of the Financial Services Authority, the Central Bureau of Statistics (Badan Pusat Statistik) and Bank Indonesia and analyzed using multiple regression methods. The research implications explain the relationship between the internal variables of the bank company (FDR, CAR and BOPO) and macroeconomic variables (Inflation, Exchange and GDP) on the NPF of Islamic banks in Indonesia so that they can be used as input for the relevant authorities in making policies to suppress NPF at a low level. The variables used can provide an overview of the role of the implementation of sharia public bank governance and existing macroeconomic conditions so that it can produce policies and provisions in the field of sharia banking that are effective and on target. The results showed that the CAR variable had a significant effect on NPF with negative influence. Whereas FDR, BOPO, exchange rate, inflation and GDP have no influence on NPF BUS in IndonesiaKeywords: Non Performing Financing, Non Performing Loan, Islamic Commercial Bank, Indonesia.
THE INFLUENCE OF INTELLECTUAL CAPITAL ON RETURN ON ASSETS AND RETURN ON EQUITY SHARIA RURAL BANK 2015 – 2017 PERIOD
Authors: Naufallita Qori , Hendratmi Achsania
Published: May 2020

ABSTRACT Purpose of this study is to determine the effect of Human Capital Efficiency, Capital Employed Efficiency, and Structural Capital Efficiency on Return On Assets and Return On Equity of Islamic Rural Banks period 2015-2017. This study uses a quantitative approach. Sampling technique is purposive sampling and there were 24 Islamic Rural Banks in Indonesia as subject of research. Analysis technique used is Panel Data Analysis.The results of this study indicate that CEE has a significant positive effect on ROA. Whereas HCE and SCE have no effect on ROA. Simultaneously HCE, CEE and SCE have a significant positive effect on ROA. In addition, the results of this study indicate that HCE and CEE have a significant positive effect on ROE, both partially and simultaneously.ABSTRAKPenelitian ini bertujuan untuk mengetahui pengaruh Human Capital Efficiency (HCE), Capital Employed Efficiency (CEE) dan Structural Capital Efficiency (SCE) pada Return On Assets dan Return On Equity Bank Pembiayaan Rakyat Syariah periode 2015-2017. Penelitian ini menggunakan pendekatan kuantitatif. Pengambilan sampel menggunakan purposive sampling dan terdapat 24 BPRS yang menjadi subyek penelitian. Teknik analisis menggunakan analisis Regresi Data Panel.Hasil penelitian menunjukkan CEE berpengaruh signifikan positif terhadap ROA. Sedangkan HCE dan SCE tidak berpengaruh terhadap ROA  Secara simultan HCE, CEE dan SCE berpengaruh signifikan positif terhadap ROA. Selain itu, hasil penelitian ini menunjukkan bahwa HCE dan CEE berpengaruh signifikan positif terhadap ROE, baik itu secara parsial maupun simultan.
MUSLIM COMMUNITIES PREFERENCE THAT DO NOT USE SHARIA PAWNSHOP
Authors: Khoiriyah Siti Sabilah , Paramita Metti , Pangestu Raden Ali
Published: May 2020

This study aims to determine what factors influence the preferences of Muslim communities who do not use sharia pawnshops. The research method uses a quantitative approach with logistic regression analysis techniques. The technique of collecting data using questionnaires originating from 100 Muslim communities in West Bogor District. Based on the results of the analysis of the data obtained it can be seen that only locations that have an influence on the decisions of Muslim communities so that they do not use sharia pawnshops because the location has a significance level smaller than 0.05, which is equal to 0.02.
«Chinese» market in the space of a Russian city (the case of Chelyabinsk)
Authors: Avdashkin A.A.
Published: May 2020

This article is focused on the problem of formation and development of «Chinese markets». Most of the aca-demic texts on the issue are based on materials from the Irkutsk «Shanghai» market. «Chinese markets» of the Ural cities have not been explored. The purpose of this manuscript is to trace the formation and development of ideas about the «Chinese market» among the residents of a large Ural city using the example of Chelyabinsk. The source base includes the author’s personal observations made in the Chinatown area (vicinity of the «Zare-chny Market»), archival documents on migration and trade between China and Chelyabinsk Oblast. In 2019 the author gathered interviews with consumers of the «Chinese» market, apartment owners who rented out housing to the Chinese, and market workers. The Chelyabinsk and all-Russian press are important sources for studying public opinion regarding the «Chinese» markets. The complexity of the study object resulted in the use of a com-plex of methods. These are free informal interviews with city dwellers, included observation in the «Chinese mar-ket», analysis of press content and discourse. Our study of perception of the «Chinese market» showed a lot in common between the emergence of «Chinese markets», and, most importantly, the reaction of the host commu-nity in Chelyabinsk and Siberian cities to this process. In the media discourse and in the mass consciousness of the townspeople, ideas about the «Chinese market» created an image of a «Chinatown» and a large number of Chinese migrants. Around the market, a complex of perceptions of threats has been formed (crime, tax evasion, low-quality goods, etc.). The Chinese market has formed complex networks of social relations between traders and consumers, the host society and migrants. The term of «Chinese market» has incorporated a large number of meanings that are understandable without additional explanation: from organization of urban space to a set of markers that determine social status. Today, the «Chinese market» is the image of the «East» for citizens, where different ethnic groups, borders, and cultures are intertwined.
The myth of the journey of the soul and Bronze Age funerary sites of the Sintashta
and Petrovka type in the Southern Trans-Urals
Authors: Vinogradov N.B.
Published: May 2020

The article presents an attempt to interpret the semantics of one of the brightest examples of the burial rite among the pastoral population with high level of metal production, which left the sites of the Sintashta and Pet-rovka type, localized in the Southern Trans-Urals (Trans-Ural peneplain). They are presently dated to the period between the 21st and 18th c. BC (transitional time from the Middle to Late Bronze Age). Materials from the burial sites (cemeteries of Sintashta and Krivoye Ozero) have been analysed, with direct involvement of the author. The problem appears as follows. The vast majority of researchers believe that within the burial chamber of some Sin-thashta and later Petrovka socially significant persons, the chariots were placed, in an assembled or disassem-bled form, yet chariots. The main purpose of the chariots, in their opinion, was participation in military activities, with a caveat about the possibility of their use in rituals, and that the buried themselves should be recognised as chariot drivers-warriors who ruled the life of communities (clans). The article substantiates the hypothesis of the apparent existence of a tradition in the Sintashta, Petrovka and other synchronous Eastern European steppe cul-tural formations, of placing in the burial chamber the very parts of a chariot, especially the wheels, and not the whole chariots. The author suggests considering the funeral rite of the chosen members of the Bronze Age Sin-tashta and Petrovka communities (clans) of the Southern Trans-Urals, which involved the use of chariot parts (wheels), as a kind of symbolic text, as a modelled realization of the funeral myth, which tells the story of the jour-ney of the soul to the afterlife on the burial chariot of the Vedic twin gods — Ashwins. The detailed parameters of such models should not be literally correlated with the real transportation means. According to the author, the individuals buried in such tombs were not necessarily chariot drivers-warriors. The paper discusses another im-portant aspect — the localization of the other world for the Bronze Age Sintashta and Petrovka population of the Southern Trans-Urals. According to our observations, the ideas about the localization of the world of the dead were not permanent and could change over several centuries, from the Sintashta period to the time of the classi-cal stage of the history of the Alakul Culture (pottery with a ledge shoulder, with ornamentation spread across two or three zones). The majority of adults in the Sintashta burials with wheel hollows, were orientated with their heads to the northwest sector. Similar was the orientation of symbolic wagons and equally symbolic horses. For alike Petrovka burial sites, the latitudinal orientation already prevailed. These changes, as it appears to the
author, reflect modifications of the funeral myth.
Cave burial of Urd Ulaan Uneet (Mongolian Altai):
рotential of cultural-chronological interpretation
Authors: Seregin N.N. , Matrenin S.S. , Iderkhangai T.-O.
Published: May 2020

The article considers the materials of the Urd Ulaan Uneet cave burial, investigated in 2015. This complex is located in the Tsagaanbulag Myangad Somon of Kobdo Aimak of Mongolia, at the altitude of 1327 m a.s.l. Pre-sented is the description of the circumstances of discovery of this important site, as well as the existing experi-ence of studying and publishing of the materials. The main objective of the study is the detailed analysis of the main categories of finds from the cave burial, the most informative of which include wooden saddle, iron bits with horn psalia, compound bow, arrowheads, leather quiver with iron hook, and wooden vessel. For the interpretation of these items, extensive archaeological sources of the Syanby-Rouran and medieval time, assembled during the excavations in various parts of the Central Asian region, were involved. Based on the results obtained, a number of conclusions have been made regarding the cultural and chronological interpretation of the site. It has been established that the Urd Ulaan Uneet complex is one of the rare objects of the Rouran time in Mongolia, and the only known cave burial of this chronological period. The monument can be confidently dated to the middle of the 4th –5th c. AD with the possible extension of the upper chronological boundary to the beginning of the 6th c. AD. This conclusion is generally supported by the results of radiocarbon analysis presented in the publications of Mongolian archaeologists. An indicative characteristic of the cave site, not revealed during the excavations of other objects of the Rouran period in Mongolia, is the accompanying burial of a horse. Obviously, this feature of the funeral rite is explained by contacts with the population of the Bulan-Koby Culture. The weighty argument in favor of the proposed possible interactions between the Altai cattle breeders and nomads of Western Mongolia in the Rouran period could be found among the investigated burials of the Bulan-Koby Culture in the Bayan-Ulgiy Aimag. The material complex found during the excavation of the Urd Ulaan Uneet cave burial reflects the very wide contacts of the population of Mongolia in various directions (Altai-Sayan Region, Trans-Baikal Region, Man-churia, East Turkestan, Central Asia) in the middle of the 1st mil. AD. In addition, the «western» relations are clearly distinguishable; these obviously demonstrate the complex migration processes of the Great Migration
Period.
Pottery from the Vak-Kur cemetery of the Yudina Culture
(based on materials from excavations 3–6)
Authors: Turova N.P.
Published: May 2020

Researchers associate the medieval archeological artifacts of the Middle Trans-Urals, whose pottery bears cord impressions, with the Chiyalik, Molchanvo and Yudina Cultures. Despite the large number of artifacts that have been studied, many questions remain open. These include the status, chronology, and interaction of the Molchanovo and Yudina antiquities, as well as the evolution and specifics of their pottery complexes. Publication and analysis of the ceramic collections from Vak-Kur, the largest burial ground of the Yudina Culture, contribute to addressing some problems related to «the Corded Ware cultures». The Vak-Kur burial ground is dated to the 10th–11th centuries based on the assemblage of the associated goods. It is located in the south-eastern part of the Yudina Culture areal, on the right shore of the Tobol River. For all the time of excavations in the area of the ne-cropolis, 220 burials have been studied. The dead were buried in shallow pits according to the ritual of inhuma-tion, on their backs. A specific feature of the funeral ritual is breaking of a part of the accompanying equipment and use of funerary masks. Decorative and morphological features of 143 Yudina vessels have been examined. The tableware has been categorized according to four topographic groups after excavations 3 to 6. It has been noted that, despite the similar shapes of pots, and ornamental proportions and patterns, the pottery from excava-tions 3 to 6 demonstrates a different frequency in use of such elements in the décor as the cord and figured stamps. The biggest differences were detected between the ceramic artifacts found in excavations 4 and 6. It was suggested that the differences in décor between pottery from different excavations are determined not by their asynchronous nature, but by the existence of several tribal sites in the area of the Yudina necropolis. The com-parison of ceramic collections from the Vak-Kur burial ground with those from the medieval burial and settlement sites of the Yudina Culture showed that the pottery from the necropolis is most closely related to collections from the Plamya Sibiri 6 and 7, and Antonovo 1 settlements located in the Tura River basin. These sites were dated by their investigator to the earlier period (6th to 9th centuries) and attributed to the Molchanovo Culture. Based on the significant similarity between the pottery of the named sites and the dishware of the 10th to 11th centuries from excavation 4 of the Vak-Kur burial ground, a revision of the chronology and cultural attribution of these sites has been proposed.
Corona Virus Disease 2019 (COVID-19) Pandemic Up-to-Date Facts, Opportunities and Challenges: A review on Cases in Ethiopia
Authors: Misganaw Chanie Derso
Published: May 2020

There are many types of coronavirus on the bases of important hosts including human, rat, turkey, rabbit, etc. The virus looks like a crown or corona of the sun with its round projection, spike. Now a day, newly emerged coronavirus disease (COVID 19) was first detected at Wuhan, China in December 2019 and it became a public health emergency international concern. Although a couple of researches has been conducting, much secretes of the virus and disease is still not understood and not reached a common understanding yet. However, sharing basic information is crucial based on the existing published research articles and updated information. Therefore, this review aimed to draw attention to the COVID 19 pandemic facts, opportunities, and challenges based on up to date information on cases in Ethiopia. Accordingly, the coronavirus is a single-stranded, non-segmented RNA genome virus. Two third of the genome (5'end) consists of two genes that code nonstructural proteins and the other 2-7 genes (3' end) code structural proteins including spike, envelope, membrane, and nucleocapsid. The virus transmits from animal to human and suggested as it might be originated from a bat and/or seafood. Coronavirus transmit human to human by direct contact and droplets during coughing and sneezing and common symptoms like fever, dry cough, and tiredness, short breathing, etc. can be seen from the patient. So that stay at home and social distancing are the most practicing pre-prevention methods. The disease causes high economic loss, face to face education closure, community cultural practice, and mass gathering activities are prohibited. However, various charity associations and creativities found increase than before. To this end, peoples should accept and follow governmental advice and instructions to escape from the pandemic.
COVID-19 Crisis: An Update on the Disruption of Clinical trials
Authors: Kumar Vijay
Published: May 2020

COVID-19 is causing major turmoil around the globe, and the clinical trial industry is likely to face unprecedented challenges to health and business sectors. In an effort to find a suitable treatment and prevention options for COVID-19, several COVID-19 clinical trials are being planned and initiated, while a large number of clinical trials for non- COVID-19 indications are suffering delays. With over more than 1000 trials being disrupted and more trials being added to this category daily, there is a direct impact on trial site activation and patient enrolment. This analysis deals with the specific impacts of the COVID-19 pandemic on the clinical trial and pharmaceutical industry. The objective of this study is to provide an updated information of the disrupted clinical trials and its impact on various therapeutic areas and different drugs. Among the severely affected clinical trials, oncology and CNS trials are the hardest hit therapy areas.This article will certainly emphasize the need for advanced and innovative approaches to maintain the health of the clinical trial ecosystem by continuing the existing trials and the start of the new studies. We have to take and follow necessary actions to guarantee that the initiatives will not be locked during the COVID-19 pandemic, both for the treatment of patients and for the researchers to conduct decision-relevant clinical trials.
The Effect of Curing Conditions on Selected Properties of Recycled Aggregate Concrete
Authors: Grabiec Anna M. , Zawal Daniel , Rasaq Waheed Adewale
Published: May 2020

The paper presents the influence of different curing conditions – wet, dry and protection against water evaporation on selected properties of concretes with different amount of recycled concrete aggregate previously subjected to atmospheric CO2 sequestration. Additionally, the eco-efficiency bi and ci indexes as well as eco-durability S-CO2 index were calculated. It was found that dry conditions deteriorate the properties of concrete, especially made of blast furnace slag cement, while protection against evaporation allows to achieve results comparable to wet conditions. Moreover, for series with the highest amount of coarse recycled aggregate and after longer period of curing, the difference between the effects of wet curing and protection against water evaporation disappears. The eco-efficiency and eco-durability indexes approach confirms the beneficial effect of blast-furnace slag cement used as a binder but on condition of proper way of curing.
Isolation of Neural Crest-derived Stem Cells for Therapeutic Use in Regenerative Periodontology
Authors: Grimm Wolf-Dieter , Didenko5 Nikolaj , Dhingra Kunaal , Dolgalev Alexander , Enukashvily Natella , Fritsch Tilman , Giesenhagen5 Bernd , Ivolgin Dmitriy , Vukovic Marco Alexander
Published: May 2020

Periodontitis is microbial infection affecting periodontium, the tooth supporting structure and affects >743 million people worldwide. Neural crest-derived stem cells (NCSCs) hold the promise to regenerate the damaged periodontium. These cells have been identified within adult adipose tissue, periodontal ligament, and palatal tissue. Typical enzymatic isolation protocols are expensive, time consuming and often not clinically compliant. Enzyme-free, mechanical dissociation has been suggested as an alternative method of generating cell suspensions required for cell separation and subsequent expansion ex vivo. In our study, samples of rat skeletal muscle tissue were used to appraise the suitability of a novel mincing method of mechanical dissociation against enzymatic digestion with collagenase and dispase. Skeletal muscle is readily available and has been shown to contain NCSC populations. We used a Rigenera-Human Brain Wave® prototype mincer to produce a suspension of NCSCs. We have compared the resulting cell cultures produced via mechanical dissociation and enzymatic dissociation, producing single cell suspensions suitable for Magnetic Cell Sorting (MACs) and Fluorescence-activated cell sorting (FACS). Despite the Countess Automated Cytometry data demonstrating that cell suspensions produced by mechanical dissociation (n=24) contain on average 26.8 times as many viable cells as enzymatic cell suspensions (n=18), enzymatic suspensions produced more successful cell cultures. Spheroids and subsequently adherent cells formed from 4 enzymatic cell suspensions (44.4%) vs. 1 mechanical cell suspension (8.3%). Enzymatic digestion protocols formed spheroids faster and more plentifully than mechanical cell suspensions. Adherent cells and spheroids isolated via both methods appear morphologically similarly to NCSCs from our previous studies.
IPTEK BAGI DESA BERBASIS SISTEM APLIKASI AKUNTANSI MENUJU DESA WIRAUSAHA
Authors: Nugrahaningsih Putri , Suranta Sri
Published: May 2020

Penelitian ini bertujuan untuk mendorong terciptanya aparatur pemerintahan desa yang mampu, terampil, dan profesional dalam pengelolaan Dana Desa, sehingga  pemanfaatan dana tersebut lebih optimal. Selain Sumber daya Manusia yang handal juga harus dibekali prasarana penunjang Iptek. Metoda penelitian yang digunakan adalah deskriptif kualitatif, dengan teknik pengumpulan data meliputi focus group discussion, in-depth interview, observasi dan dokumentasi di desa Bulusulur, Kabupaten Wonogiri.

Hasil penelitian menemukan bahwa implementasi Dana Desa dilakukan dengan Pembentukan Badan Usaha Milik Desa (BUMDes) yang memiliki empat unit Usaha. Untuk menjawab kebutuhan BUMDes akan akuntabilitas, transparansi, dan informasi, maka diimplementasikan Program aplikasi Sistem Informasi Akuntansi Keuangan BUMDes berbasis website untuk kemudahan penginputan dan pengolahan segala data transaksi keuangan, serta penyusunan pelaporan keuangan BUMDes. Aplikasi ini dikembangkan sebagai dedikasi untuk mendorong terbangunnya keterbukaan informasi publik di Indonesia untuk tata kelola keuangan BUMDes yang makin profesional, akuntabel, dan transparan.
Pemberdayaan Relawan Dalam Upaya Penanggulangan Kekerasan Terhadap Anak di Pimpinan Cabang Aisyiyah Kraton Yogyakarta
Authors: Marwati Triyani , Ruliyandri Rochana , Solikhah Solikhah
Published: May 2020

ABSTRAK

Kekerasan anak di Indonesia semakin meningkat setiap tahunnya. Tahun 2011 terjadi 2178 kasus kekerasan, 2012 ada 3512 kasus, 2013 ada 4311 kasus, 2014 ada 5066 kasus (KPAI, 2015).Hal ini terjadi salah satunya karena dari sisi kelembagaan gerakan perlindungan anak belum berjalan optimal karena pemahaman akan pentingnya perlindungan anak dari para pemangku kepentingan (stakeholder), baik dari para pengambil kebijakan, penyelenggara, dan masyarakat, masih terbatas.Tujuan dari pengabdian masyarakat ini membentuk kelompok relawan perlindungan kepada anak dari ibu-ibu pengurus PCA Kraton sehingga relawan tersebut dapat mengkampanyekan tentang perlindungan anak kepada orangtua maupun kepada masyarakat umum dan meningkatkan pemahaman dan kemampuan relawan mempraktekkan ilmu terkait hak-hak anak.

Materi yang disampaikan antara lain dampak kekerasan terhadap anak, mengenali tanda-tanda kekerasan terhadap anak, ketahanan keluarga dengan konsep keluarga sakinah, paralegal, parenting  orang tua & anak korban kejahatan seksual, prinsip dasar dalam kerja pendampingan anak korban kekerasan & kode etik, prinsip dasar dalam kerja pendampingan anak korban, faktor resiko & penyebab kekerasan, peran keluarga untuk pencegahan, langkah-langkah pendampingan terhadap kekerasan anak, pertolongan pertama psikologis dan alur layanan pendampingan anak korban kekerasan melalui power point dan modul pelatihan. Metode pelaksanaan kegiatan ini menggunakan TOT atau training relawan perlindungan anak di wilayah PCA Kraton.

Pelatihan pemberdayaan relawan dalam upaya penanggulangan kekerasan terhadap anak di Pimpinan Cabang Aisyiyah Kraton Yogyakarta mampu meningkatkan dan kemampuan relawan mempraktekan ilmu terkait hak-hak anak. Hal ini dibuktikan setelah dilakukan ToT terbentuk relawan perlindungan anak yang dinama GACA ( Gerakan Aisyiyah Cinta Anak ) terdiri dari berbagai unsur majelis seperti majelis  hukum dan HAM, majelis soial, majelis tableq, majelis dikdasmen , majelis kebudayaan dll serta telah menetapkan program kerja.

Kata kunci : penanggulangan kekerasan, anak korban kekerasan

 
Pemanfaatan Tanaman Daun Gatal di Arso XIV
Authors: Simaremare Eva Susanty , Pratiwi Rani Dewi , Gunawan Elsye
Published: May 2020

Wulukubun Arso XIV, District Skanto Kerom regency is overgrown with stingging nettle leaves that are useful as traditional medicine as pain relief, reduce fatigue, and reduce stiffness. Stingging nettle leaves are found in the village but they are only allowed to dry, wilted, dead, even thrown away. On the other hand the value of this leaf is higher if they are developed as pharmaceutical products. The purpose of this activity was to carry out a program to empower, strengthen community participation in swamedication and optimization the potency of stingging nettle leaf to raise the health and economics of Wulukubun Arso XIV people as topical ointment. This activity was taked out by the preparation method, established cooperation with partners, related institutions, activities of the activity day in the village, evaluation, report, and publication. The results showed 7.4% of participants have followed the same activity. As many as 88.9% of participants got new information from this activity and 70.4% committed to assist others in disseminating the information from this activity
Konsep Reduce, Reuse, Recycle dan Replace dalam Pengelolaan Sampah Rumah Tangga di Desa Polanharjo Kabupaten Klaten
Authors: Istiqomah Nurul , Mafruhah Izza , Gravitiani Evi , Supriyadi Supriyadi
Published: May 2020

Indonesia merupakan negara penyumbang sampah plastik terbesar kedua di dunia setelah China. Berdasarkan data dari Kementerian Lingkungan Hidup dan Kehutanan (KLHK), diperkirakan jumlah sampah Indonesia pada tahun 2019 adalah sebesar 68 juta ton, dan sampah plastiknya mencapai 9,52 juta ton atau mencapai 14% dari total sampah yang ada. Pengelolaan sampah anorganik yang berupa botol, kertas, plastic, kaleng dan sampah bekas alat elektronik sifatnya lebih sukar terurai oleh organisme sehingga bertahan lama menjadi sampah. Terdapat berbagai cara untuk mengatasi masalah tersebut, yaitu 3R (Reduce, Reuse, dan Recycle). Sampah yang bisa diangkut ke TPA di Klaten setiap harinya hanya berkisar 70% dari sampah yang ada, dan yang bisa diolah menjadi kompos dan daur ulang sampah anorganik hanya berkisar 2 %, sedangkan sisanya ditimbun sebesar  10 %,  dibakar sebesar 10 % dan besarnya sampah yang tidak terangkut adalah 8 %. Polanharjo merupakan salah satu daerah di Kabupaten Klaten yang sudah mengkoordinasi pemanfaatan sampah anorganik secara komersil, salah satu pelaku pemanfaatan sampah didaerah tersebut adalah Bank Sampah Rukun Santoso.

Bank Sampah Rukun Santoso merupakan salah satu bank sampah yang bisa mengelola dengan baik sampah yang dikumpulkannya, tetapi masih menghadapi beberapa kendala. Kendala-kendala tersebut adalah belum adanya variasi terhadap produk olahan sampah yang dihasilkan, karena baru bisa mengolah sampah berbahan dasar plastis pembungkus minuman instan saja. Sampah yang berupa kertas masih dijual secara kiloan, padahal mempunyai potensi untuk diolah dan mendapatkan nilai tambah yang lebih tinggi. Pemasaran yang dilakukan masih tradisional, dimana produk hasil olahan sampah hanya dipajang pada etalase di salah satu teras rumah pengurus dari bank sampah, sehingga diperlukan pelatihan untuk pemasaran yang lebih modern serta perlunya brand awareness pada produk olahan sampah tersebut.
Tujuan dari pengabdian ini adalah melakukan pelatihan bagi anggota dan pengurus Bank Sampah di Desa Polanharjo untuk membuat produk baru sebagai usaha diversifikasi terhadap produk yang sudah ada untuk kemajuan usaha mereka dengan bahan baku kain perca, karena selama ini yang diolah hanya sampah plastis yang berupa bekas pembungkus minuman kemasan saja.
Could the Stock Market Adjust Itself? An Empirical Study Based on Mean Reversion Theory
Authors: Li Shuangjie , Hu Xuefeng , Wang Liming
Published: May 2020

This paper mainly studies whether and how stock prices fluctuate around their intrinsic values. Based on data from 10 stock markets for the period between 2000 and 2018, we demonstrate that the relative price fluctuates around and approaches the intrinsic value in the long term. For the ten markets, the relative price crosses the intrinsic value on average once in 3 ∼ 4 years. Profitability growth is a key factor in rising stock prices, but the level of valuations in the market has a regulatory effect to the growth of price in the future: For every 1 % increase in valuation, the price tends to decline by 0.26% in the next year, 0.74% in the next 3 years.
How to Bid Success in Crowdsourcing Contest? ― Evidence from the Translation Tasks of Tripadvisor
Authors: Dong Kunxiang , Sun Yan , Xie Zongxiao , Zhen Jie
Published: May 2020

Material incentive is the main motivation for solvers to attend crowdsourcing tasks. So raising the bidding success rate is benefit to inspire the solvers attendance’ and increase the answering quality. This paper analyzes the effect of participation experience, task-fit capability, participation strategy and task attribute on the solvers bidding success by the solvers attending the series tasks of Tripadvisor. The results show that: 1) Participation times enrich the participation experiences and promote the bidding success, while bidding success times and last performances lower the bidding success because of the cognitive fixation; 2) The chance of bidding success will be increase when the solver own high task-fit capability; 3) The relationship between task submit sequence and bidding success is the type of reverse U shape, and the optimal submit sequence rate on the top of the reverse U shape; 4) Higher task difficulty lower bidding success, while higher task density easier bidding success.
POSTAWY WOBEC NIEPEŁNOSPRAWNOŚCI FIZYCZNEJ W OKRESIE ŚREDNIOWIECZA
Authors: Kolwitz Marcin , Dąbrowski Szymon
Published: May 2020

–
TRĄDZIK POSPOLITY – ETIOLOGIA, KLASYFIKACJA, LECZENIE
Authors: Janda Katarzyna , Chwiłkowska Magdalena
Published: May 2020

A spotless skin is a rarity. Both women and men have different problems related to the complexion. One of the most common problems is acne, which affects an increasing number of people of all ages. Seborrhea skin areas rich in sebaceous glands, the formation of comedones, inflammation, and scars are characteristic for this disease. The aim of the study was to discuss the causes of acne vulgaris, methods of treatment, and proper care of the skin affected by this problem.
MOLEKULARNY MECHANIZM DZIAŁANIA RESTRYKCJI KALORYCZNYCH
Authors: Gawęcka Alicja , Stachowska Ewa
Published: May 2020

The use of caloric restriction modulates the activity of FoxO proteins. FoxO is a key regulator of changes in the metabolism of carbohydrates. Under the influence of limited access to food FoxO proteins are activated. FOXO activation is done by deacetylation. The enzymes responsible for the deacetylation of proteins are called sirtuins. Sirtuins are NAD­‍‑dependent proteins, the activity of which is dependent on the metabolic status of the cell. Deacetylation of FoxO leads to an increase in the potential for increased interaction with DNA. In vivo studies have shown that under the influence of calorie restriction sirtuin levels increase in muscle, brain, kidney, or adipose tissue.
CZY CHORYCH NA OLBRZYMIOKOMÓRKOWE ZAPALENIE TĘTNIC BADAĆ W KIERUNKU ROZWOJU TĘTNIAKÓW AORTY?
Authors: Milchert Marcin , Brzosko Marek
Published: May 2020

Aortitis is one of the manifestations of giant cell arteritis (GCA) and is included in its definition. There is a significantly increased risk of aortic aneurysm formation in GCA patients. In some GCA patients aortic aneurysm dissection is diagnosed only in autopsy. Monitoring of these patients, especially in long lasting disease, requires a doctor’s awareness of the possibility of aneurysm formation and aortic aneurysm dissection. Based on the available reports it cannot be confirmed whether intensification of aortitis treatment in GCA prevents the development of aneurysms. This article presents an overview of the available literature and our own experience on a rational diagnosis of inflammation and aneurysms of the aorta in GCA, as well as the prospects for its prevention.
POSTĘPY W PATOGENEZIE, DIAGNOSTYCE I LECZENIU UKŁADOWYCH ZAPALEŃ NACZYŃ ZWIĄZANYCH Z PRZECIWCIAŁAMI PRZECIWGRANULOCYTARNYMI
Authors: Zdrojewski Zbigniew
Published: May 2020

Antineutrophil cytoplasmic antibody­‍‑associated vasculitis (AAV) is a group of systemic diseases characterized by necrotizing inflammation of small and medium size vessels, without immunologic deposits, and with the presence of specific serum antibodies. Recent genetic and cohort studies should improve the comprehension of the pathogenesis of AAV, the stratification of patients into homogenous groups, and lead to therapeutic implications. Immunosuppressive therapy of AAV includes two major periods: induction of remission and maintenance therapy. Therapy should be chosen individually, not only depending on the stage and severity of the disease, but also on genetic and some prognostic factors. Previous randomized trials and clinical observations show some possible limitations of treatment with cyclophosphamide and steroids. Rytuximab seems to be a good alternative in those patients in induction therapy as well as in maintenance therapy.
OPINIE POLAKÓW O WSPÓŁPŁACENIU ZA LECZENIE SZPITALNE ORAZ O DOPŁATACH DO ŚWIADCZEŃ PONADSTANDARDOWYCH
Authors: Kemicer-Chmielewska Ewa , Rotter Iwona , Kotwas Artur , Karakiewicz Beata
Published: May 2020

Introduction: Co-payment in the health sector operates in most healthcare systems in European countries. The aim of this study was knowledge of Polish citizens’ opinions concerning healthcare services co­‑payment with respect to selected socio­‍‑demographic factors.Material and methods: The study was conducted using a diagnostic survey of 636 respondents, representing residents of the West Pomeranian region, Poland.Results: The majority of respondents did not accept co­‍‑payment for health services.Conclusions: Material situation and educational background impact on decisions concerning co­‍‑payment for hospital treatment.
Assessment of parental knowledge of daily skin care of children under three years
Authors: Kuba Justyna , Marchlewicz Mariola
Published: May 2020

Introduction: The skin is an organ which plays many important functions. It is e.g. a highly specialized barrier and protects against mechanical trauma and UV radiation. Moreover it participates in the synthesis of vitamin D and also participates in the immune system. The skin of a newborn needs specific treatment due to its functional and anatomical differences. Skin of the baby achieves similarity to adult skin in 3 years old child. Signifficant difference included higher body surface vs. volume ratio which increases the permeability for potentially undesirable substances. Moreover the thinner stratum corneum of the epidermis and neutral pH provides insufficient protection against irritations and microorganisms. Therefore the skin of the newborn requires special care and cosmetics as well as application of skin care methods which should take into account morphological and anatomical dissimilarity.

Materials and methods: The study was conducted on 125 parents, living in the West Pomeranian region, on the basis of the diagnostic survey method, using the author’s questionnaire survey.

Conclusions: The parents have awareness about the composition nursing products and cosmetics. For the respondents, the internet and the doctor were the most important sources of information about child skin care.
The incidence of insomnia among employed and unemployed individuals
Authors: Wolińska Weronika
Published: May 2020

Introduction: Insomnia is a complex disorder and requires knowledge of the subjective feelings of the patient. The incidence of insomnia varies depending on the classification and definition used in the study, and usually oscillates between 4–48%. Insomnia lowers quality of life (QoL), which translates into poorer functioning at social and professional levels.

The aim of this study was to determine the incidence of insomnia among employed and unemployed individuals with regard to their sociodemographic and socioeconomic data, to analyze the relationship between insomnia, depressive symptoms and chronic diseases, and to assess how insomnia affects QoL.

Materials and methods: This survey-based study included 597 people. The following questionnaires were used: the Athens Insomnia Scale (AIS), Beck’s Depression Inventory (BDI), the Short Form 36 Health Survey (SF-36), and a self-developed questionnaire.

Results: Insomnia was found in 17.75% (n = 106; p ≤ 0.001) of respondents. There was a statistically significant relationship between insomnia and sex (p = 0.006). Insomnia was more common in women (20.83%; n = 75), people over 56 years of age (27.08%; n = 26; p ≤ 0.001), and those unemployed (26.37%; n = 53; p ≤ 0.001). A statistically significant relationship was demonstrated between depression and insomnia assessed by the AIS (p ≤ 0.001).

Conclusions: 1. Insomnia was more common in unemployed individuals. 2. Insomnia was more common in those with hyper-tension, irrespective of their employment status. Therefore, primary care physicians should use the AIS as part of screening among chronically ill patients. 3. Insomnia was accompanied by depressive symptoms in all groups analyzed in this study, irrespective of their employment status. 4. Insomnia is a serious public and mental health problem. The AIS should be used as part of workers’ periodic health examinations, since ignoring the problem of insomnia decreases QoL.
BLASTOCYSTIS HOMINIS – KOMENSAL CZY PATOGEN?
Authors: Duda Aleksandra , Kosik-Bogacka Danuta , Łanocha Natalia , Szymański Sławomir
Published: May 2020

Blastocystis hominis (B. hominis) is a cosmopolitan protozoa which parasitizes the human large intestine. This parasite had been considered to be commensal of the large intestine for a long time, because even an intense invasion may be asymptomatic. However, this species is now being regarded as a parasitic organism. In this paper the latest data concerning the epidemiology, diagnostics and treatment of B. hominis invasion have been cited and discussed.
PLEJOTROPOWE DZIAŁANIE INHIBITORÓW 3-HYDROKSY‑3-METYLO-GLUTARYLO-KOENZYMU A (STATYN). POTENCJAŁ LECZNICZY W UKŁADOWYCH CHOROBACH TKANKI ŁĄCZNEJ
Authors: Kotyla Przemysław J.
Published: May 2020

3­‍‑Hydroxy‑3­‍‑Methyl­‍‑Glutharyl­‍‑Coenzyme A reductase inhibitors, known as statins, form a group of chemical compounds that are characterized by the ability to inhibit cholesterol synthesis. Statins have proved their efficacy as potent drugs in the primary and secondary prevention of cardiovascular events. It has also been shown that the therapeutic effects of statins go beyond reduction of cholesterol level. These properties, which are separate from the influence on cholesterol synthesis, are sometimes called the pleiotropic effect. This effect comprises immunomodulation, an anti­‍‑inflammatory effect, and endothelial function recovery.