bluuebunny/crossref_metadata_2025 huggingface dataset:
Líðan leikskólakennara og leiðbeinenda í leikskólum í kjölfar efnahagshrunsins
Authors: Rafnsdóttir Guðbjörg Linda , Sigursteinsdóttir Hjördís
Published: February 2020

Líðan leikskólakennara og leiðbeinenda, svo og aðbúnaður á vinnustað, er meðal þess sem getur haft áhrif á leikskólabörn og þroskaferil þeirra. Því er brýnt að rannsaka líðan þessara starfshópa og hvaða þættir í vinnuumhverfinu styðja við eða draga úr góðri líðan starfsfólksins. Það er viðfangsefni þessarar greinar. Vinnufyrirkomulag um það bil helmings allra leikskólakennara og leiðbeinenda, sem starfa hjá sveitarfélögum hér á landi, er rannsakað, svo og tengsl þess við sjálfmetna andlega líðan þeirra. Meginrannsóknarspurningin er hvort tengsl séu á milli þess hvernig leikskólakennarar og leiðbeinendur upplifa vinnufyrirkomulagsþætti eins og stjórnun, stuðning, vinnuálag, skilgreiningu hlutverka og þróun í starfi annars vegar og andlegrar líðanar þeirra hins vegar. Greinin byggir á langtíma panelgögnum þar sem sömu 480 leikskólakennurum og leiðbeinendum var fylgt eftir árin 2010, 2011, 2013 og 2015. Notað var svokallað GEE-líkan (e. generalized estimating equation) til að spá fyrir um andlega líðan starfsfólksins á þessum árum. Niðurstöðurnar gerðu almennt ekki greinarmun á leikskólakennurum og leiðbeinendum. Endurteknar mælingar sýndu að sjálfmetin andleg líðan leikskólakennaranna og leiðbeinendanna versnaði á milli fyrirlagna. Þetta kom einnig fram þegar tillit hafði verið tekið til kyns, aldurs og hjúskaparstöðu. Allir þættir í vinnuumhverfinu, sem til skoðunar voru, versnuðu á milli fyrirlagna að mati starfsfólksins. Sá þáttur, sem versnaði mest, var vinnuálag. Athyglisvert er þó að tengslin voru veik á milli vinnuálags og andlegrar líðanar. Góð stjórnun og félagslegur stuðningur hafði jákvæð áhrif á líðanina. Mikilvægt er að þeir sem standa að stefnumótun á sviði leikskólanna taki þessar niðurstöður til skoðunar og að greint verði enn frekar hvað veldur því að áðurnefndir vinnufyrirkomulagsþættir og líðan starfsfólksins versna að þeirra mati á milli fyrirlagna. Með því móti er ekki einungis stuðlað að bættu vinnuumhverfi leikskólakennara og leiðbeinenda heldur einnig leikskólabarnanna og að leikskólabörnunum sé sinnt á þann hátt sem nauðsynlegt er fyrir líðan þeirra og þroska.
Algunas notas sobre la conflictividad en las prisiones catalanas
Authors: Navarro Villanueva Carmen
Published: February 2020

En este trabajo se presentan las conclusiones de un estudio sobre la conflictividad en los centros penitenciarios catalanes. además de los datos sobre infracciones cometidas, sanciones impuestas y acuerdos recurridos durante los años 2008 y 2009, se lleva a cabo un análisis minucioso del contenido de los expedientes deisciplinarios abiertos durante esos dos años en la prisión de Quatre Camins, estudiando la manera concreta en que se cometen las infracciones y señalando cuáles son las más frecuentes y qué sanciones se imponen con mayor asiduidad. El estudio destaca asimismo el escaso uso que hacen los internos de los recuersos ante el Juez de Vigilancia Penitenciaria, analizando las posibles causas de este fenómeno. Por último, se incluyen algunas propuestas que pueden contribuir a mejorar el procedimiento disciplinario penitenciario.
Spatial changes in the command and control function of cities based on the corporate centre of gravity model
Authors: Raźniak Piotr , Dorocki Sławomir , Winiarczyk-Raźniak Anna
Published: February 2020

The aim of this paper is to discuss changes in the spatial distribution of cities that perform the command and control function created by the largest corporations, based on the method of gravity centres. The analysis was performed both for individual sectors of the economy as well as for the global scale. A shift occurred in an easterly direction. This also pertains to sector indices, although the centroids of knowledge-based sectors, such as information technology and healthcare, shifted the most in the direction of Asia. At the same time, information technology was the only sector whose centroid shifted to the west in the study period. Moreover, the magnitude of the shift of the centre of gravity of the number of corporate headquarters in the studied cities does not converge to the shift of the centroid based on the value of the financial potential of the companies.
BUDAYA VISUAL DALAM TRADISI SIKLUS KEHIDUPAN MASYARAKAT JAWA DI TULUNGAGUNG
Authors: Setiawan Fathoni , Handayaningrum Warih
Published: February 2020

Masyarakat Jawa hari ini merupakan hasil perpaduan masyarakat indigenous dimasa lalu yang telah bertemu dengan berbagai kebudayaan dari belahan dunia lain yang dibawa oleh para penjelajah yang datang karena ketertarikan meraka baik akan produk material, maupun eksotisme kebudayaan. Salah satu hasil dari persilangan kebudayaan ini adalah berbagai budaya visual termasuk yang masih bertahan dan hidup hingga hari ini. Dalam penelitian ini penulis berupaya untuk mendeskripsikan berbagai budaya visual yang masih berlaku dan digunakan oleh masyarakat Jawa di Tulungagung. Masyarakat Tulungagung dinilai masih kental akan tradisi Jawanya, terbukti dengan masih lestarinya berbagai tradisi salah satunya yang berkaitan dengan siklus hidup. Melalui tulisan penelitian ini diharapkan akan di dapatkan pemahaman tentang budaya visual yang sering digunakan, di mana biasanya masyarakat mengambil sebuah kebudayaan secara ‘taken for granted’ tanpa mengetahui tentang budaya yang dijalankannya. Dengan dipahaminya budaya visual yang ada, maka kemungkinan untuk pengembangan dan pelestarian kebudayaan yang ada akan semakin terbuka peluangnya dan terjaga esensi dari kebudayaan itu sendiri. Untuk kedepannya ketika pemahaman tentang budaya visual tradisi mulai ditumbuhkan diharapkan hal tersebut dapat menjadi aset atau modal kreatif dalam mengembangkan budaya visual kebaruan tanpa meninggalkan esensi daripada budaya visual tradisi yang merupakan identitas bangsa.
Maíz transgénico vs agricultura ecológica: un análisis del discurso de Greenpeace México en torno a la seguridad alimentaria, la soberanía alimentaria y el derecho a la alimentación (2007-2017)
Authors: Azpíroz María-Luisa
Published: February 2020

Objetivo: la investigación analiza el discurso de Greenpeace México en torno a los conceptos de seguridad alimentaria, soberanía alimentaria y derecho a la alimentación. Metodología: se emplea una metodología cualitativa asistida por el software Atlas.ti, basada en la teoría del framing (funciones diagnóstico y pronóstico). Se analiza un total de 151 piezas de la web de Greenpeace México del periodo 2007-2017. Resultados: se describe la narrativa de los frames hallados y se exponen las palabras y expresiones clave más destacadas. Limitaciones: la investigación se limita al análisis del discurso de Greenpeace México. El estudio del discurso de otras unidades de Greenpeace permitiría valorar si la ONG mantiene un discurso homogéneo a nivel global o si hay diferencias significativas según las circunstancias locales. Conclusiones: se concluye que el discurso de Greenpeace México en torno a los conceptos “seguridad alimentaria”, “soberanía alimentaria” y “derecho a la alimentación” es claramente antineoliberal pero no refleja el debate académico respecto a dichos conceptos. Se identifican las denuncias (función de frame diagnóstico) y propuestas (función de frame pronóstico) presentes en el discurso de Greenpeace México, recreando la narrativa de cinco frames concretos. También se identifican los términos y expresiones opuestas más repetidas.
A case of Dubowitz syndrome with growth hormone deficiency
Authors: Sherif Ahmed Gamal , Masoud Ahmed Nageeb , Kotit Susy
Published: February 2020

Background:

Dubowitz syndrome is a rare multiple congenital syndrome with unknown etiology, characterized primarily by growth retardation, distinctive facial dysmorphism, cutaneous eczema, microcephaly, intellectual deficit, skeletal and genital abnormalities, abnormal hematological and endocrinal findings, and other systemic affections.

Case presentation:

We report the case of a 3-year-old male patient presenting with repeated chest infections, failure to thrive, history of low birth weight, and seasonal skin allergies. Examination revealed abnormal facial features and skeletal and genital abnormalities along with delays in social development. Cardiac echocardiography showed atrial septal defect and ventricular septal defect. Blood tests revealed low growth hormone levels, and a clonidine stimulation test confirmed growth hormone deficiency.

Conclusion:

Careful examination of the patient leads to the diagnosis of Dubowitz syndrome and growth hormone deficiency. The combination of these two findings has rarely been reported before, but patients may get the benefit of testing for growth hormone deficiency to receive proper treatment.
Memories of Past Presidents
Authors: Rode Denise L.
Published: February 2020

Six of NODA's past presidents shared their thoughts about NODA's history in a recent leadership survey compiled by Maria Sedotti of the University of Connecticut. Their responses help to convey a sense of how NODA developed over the past 30 years into a strong association which serves the diverse needs of students and orientation practitioners. The presidents responding identified professional leadership opportunities, travel to annual conferences, life-long friendships, and encouragement from colleagues as the rewards of their NODA involvement. We than them, and those who preceded and followed them, for their contributions to building the foundation of NODA.
The Transition and Adjustment to First-Year Students with Specific Learning Disabilities
Authors: Hadley Wanda M.
Published: February 2020

Students with learning disabilities are one of the fastest growing student population attending colleges and universities. Students with learning disabilities in the pre-kindergarten through twelfth grade (PK-12) educational system are protected by the Education of All Handicapped Children Act of 1975 and the Individuals with Disabilities Education Act (IDEIA) of 1990/Individuals with Disabilities Education Improvement Act (IDEIA) of 2004. Conversely, when students with learning disabilities transition to higher education they are no longer covered by these legislations. Section 504 of the Rehabilitation Act of 1973 and the Americans with Disabilities Act (ADA) of 1990 prohibit colleges and universities from discriminating against students with disabilities and mandate that accommodations be provided. The types and levels of accommodations and services offered in higher education, however, are not as extensive as those required to be provided in the PK-12 system. This article comes from a four-year study of the same group of 10 first-year students with dyslexia and/or reading problems. It chronicles their adjustments to the academic expectations of the college environment as they transitioned from high school to college. Chichering (1969; Chickering & Reisser, 1993) provies the theoretical framework for the study. The study begins durign the students' first year of college and concludes four years later when the students are seniors preparing to graduate. Questions in the study were asked of the students over a four-year period.
Effect of Media Types on the Growth of Callus Culture in Kumis Kucing Orthosiphon aristatus (Blume) Miq.
Authors: Widayat Wahyu
Published: February 2020

The lack of conventional availability of plant Kumis Kucing makes tissue culture techniques used as a solution to overcome this problem. In tissue culture, media is a major factor in producing a good crop of plantlets. Media Murashige & Skoog (MS), Lloyd & McCown Woody Plant (WPM) media was used in the induction of Orthosiphon aristatus (Blume) Miq cat whiskers callus culture, in this study also used growth regulators in the form of 2,4-D added to each-individual media. The results showed the best callus growth occurred in Murashige & Skoog (MS) media compared to the Lloyd & McCown Woody Plant (WPM) media, where the callus produced was 3.28 g on MS media.
LANGUAGE AND POWER IN A WTO DIRECTOR -GENERAL’S SPEECH - A CRITICAL DISCOURSE ANALYSIS
Authors: Mai Nga Dang Thi
Published: February 2020

The paper is aimed at exploring ideological power relations of globalization discourse through the analysis of the speech ‘The Backlash against Globalization’ of WTO’ s Director-General Mike Moore based on one of the Discourse Analysis (DA) approaches - Critical Discourse Analysis (CDA). At first, the paper sets out the theoretical framework of CDA and the concepts of power and ideology and examines the importance of Systemic Functional Grammar (SFG) in CDA. Then the paper provides readers with the social context of globalization and analyzes the speech in the light of CD.  The findings and the conclusion of the paper prove the assumption that the speech is a tool for Director-General Mike Moore to express his power and ideology in the sense that he is in higher position and confirms that globalization is inevitable and the establishment of WTO is a product of this process helping countries, communities and people face the problems and challenges.
THE CONNECTEDNESS BETWEEN ORGANIZATIONAL TIME/SPACE AND EXPERIENCED TIME/SPACE FROM THE PERSPECTIVE OF AN ONLINE DISTANCE STUDENT
Authors: Ngan Tran Thi
Published: February 2020

This research problematizes the conception of time and space in online distance education. It argues that online distance education is constructed from different times and spaces, namely those as organized by the institutions and those as experienced by the distance learners. In essence, it seeks to unfold how these organizational time and space and the experienced time and space are connected or separated, from the learners’ perspective. It employs a narrative inquiry to recount the experience of a 32-year-old British man pursuing a distance learning course. In doing this, the research aims to identify how online learners are engaged with the course that they are taking with respect to time and space, as well as pinpointing the gaps that separate them from the course. With consideration of those aspects in mind, online distance courses could be more effectively organized in such a way that enhances student motivation, commitment and resilience, thus contributing to their overall experience of digital learning.
THE ROLE OF LEARNERS’ TEST PERCEPTION IN CHANGING ENGLISH LEARNING PRACTICES: A CASE OF A HIGH-STAKES ENGLISH TEST AT VIETNAM NATIONAL UNIVERSITY, HANOI
Authors: Lan Nguyen Thuy , Nga Nguyen Thuy
Published: February 2020

Among various factors influencing foreign language learning, learners’ perception of a high-stakes language test plays a crucial part, especially when the test serves as a threshold for their university graduation.  In this study, the researcher tested a washback effect model by focusing on test-takers’ perception of the high-stakes test VSTEP in terms of test familiarity, test difficulty and test importance. On a sample of 751 Vietnamese learners of English at Vietnam National University, structural equation model was employed to validate the conceptual model. The analytical methods of Exploratory Factor Analysis (EFA), Confirmatory Factor Analysis (CFA) and Structural Equation Modeling (SEM) were used for analysis. Our empirical findings revealed that VSTEP seems to have had a pervasive impact on the participating students. Senior students’ evaluations of VSTEP acted as the largest factor in constituting the participants’ perception of VSTEP. There are positive links between test pressure and test familiarity with students' goal setting and study planning as well as their selection of learning content and materials. Meanwhile, the pressure from the test had no effect on students’ seeking opportunities to practice with foreigners, and test familiarity did not influence students’ choice of study methods and exam preparing strategies. The emerging patterns from the data also suggested that participating students preferred test-oriented learning content and activities at the cost of interactive English practices for real-life purposes.
K-Value Effect for Detecting Stairs Descent using Combination GLCM and KNN
Authors: Satria Bahari Johan Ahmad Wali , Utaminingrum Fitri , Budi Agung Setia
Published: February 2020

This study aims to analyze the k-value on K nearest neighbor classification. k-value is the distance used to find the closest data to label the class from the testing data. Each k-value can produce a different class label against the same testing data. The variants of k-value that we use are k=3, k=5 and k=7 to find the best k-value. There are 2 classes that are used in this research. Both classes are stairs descent and floor classes. The gray level co-occurrence matrix method is used to extract features. The data we use comes from videos obtained from the camera on the smart wheelchair taken by the frame. Refer to the results of our tests, the best k-value is obtained when using k=7 and angle 0Â° with accuracy is 92.5%. The stairs descent detection system will be implemented in a smart wheelchair
From e-Commerce Overall Quality to e-Loyalty: A Purchase-centred Framework
Authors: Nur Azizi Fakri Fandy , Aknuranda Ismiarta , Tolle Herman
Published: February 2020

The e-commerce market becomes one of the markets with the most promising growth. A number of studies on e-commerce have been investigated, but only a little attention is paid to the factors that may create e-commerce customer loyalty, even though customer loyalty is one of the primary keys to improve the performance of e-commerce businesses. This research offers a conceptual model focused on purchases to investigate the factors that affect customer's loyalty and when it is formed. Specifically, this paper intends to examine the relationship between the e-commerce overall quality on the perceived usefulness, perceived value, satisfaction and trust. This paper also verifies the relationship between perceived usefulness, perceived value, satisfaction and trust in the e-loyalty. The method of online survey is used for the data collection. From 1457 of the distributed questionnaires, 960 were completed and returned, resulted 65.8 percent response rate. The data is then analyzed using the Structural Equation Modeling (SEM) method. The research findings contribute to filling the knowledge gap regarding the defining factors of customer loyalty which may help the e-commerce provider in developing e-loyalty to increase e-commerce profitability.
Nepilsoņu jautājuma risināšanas problemātika no starptautisko tiesību viedokļa
Authors: Grasis Jānis
Published: February 2020

Latvijā joprojām nozīmīga problēma no starptautisko tiesību viedokļa ir nepilsoņu tiesiskais statuss un to risināšanas iespējas nākotnē. Zinātniski izsvērti šo problēmu analizē Jānis Grasis.

In Latvia, form an international law point of view, a very topical problem remains the legal status of non-citizens and ways of addressing the issue in the future. Scientifically elaborate approach to the problem analysis has been provided by Jānis Grasis.
Mediācija un sporta strīdi
Authors: Kameņecka-Usova Marina
Published: February 2020

Jāatzīst, ka pilnīgi jauna tēma Latvijas tiesību zinātnē ir dažādi sporta tiesību aspekti. Šajā krājumā jaunā tiesību zinātniece Marina Kameņecka-Usova apskata sporta strīdu un mediācijas problēmjautājumus.

It must be acknowledged that a novel topic in the Latvian law science has become various sport’s law aspects. The young law scientist Marina Kameņecka-Usova has addressed the question of sports disputes’ and their mediation tactics.
SCALE DEVELOPMENT STUDY FOR DETERMINING THE BRAND EQUITY OF ACADEMICS
Authors: PAKSOY H. Mustafa , ÖZBEZEK B. Dilek , GÜL Meryem
Published: February 2020

In today’s competitive environment, with the concept of brand starting to find its place in every area of life, human brand has become one of the prominent fields of work. On the other hand, in parallel with the changes in the social structure, the branding of and the determination of brand equity of academics who are the soul of universities and the main human element, has become a necessity. In general, the knowledge of academics, their relationships with colleagues and students are accepted as determinants of brand equity. The purpose of this conceptually designed study is to develop a scale to determine the brand equity of academics. For this purpose, a comprehensive literature study was carried out and a model was put forward to determine the brand equity of academics. According to this model, a strong brand of academics is emerging through the combination of features such as performance and popularity. A scale was then developed to determine the brand equity of academics within the framework of the research model.
Ação educativa acerca dos fatores de riscos de doenças cardiovasculares em adolescentes: relato de experiência
Authors: Figueiredo Amanda Rodrigues , Cabral Ana Beatriz Souza , Almeida Ana Caroline Oliveira , Ribeiro Márcio Alves , Araújo Maria Rute de Souza , Ferreira Milena Farah Damous Castanho , Silva Adriano Heleno Costa da
Published: February 2020

Objetivo: Relatar uma ação educativa acerca dos fatores de risco de doenças cardiovasculares em adolescentes em uma escola no município de Belém. Relato de experiência: A ação foi dividida em três momentos, no primeiro foi realizado uma roda de conversa sobre o estilo de vida dos participantes e histórico familiar. No segundo momento foi realizada uma explanação oral, com auxilio do método criado pelas autoras sobre como ocorre o processo fisiopatológico da aterosclerose. Por fim, no terceiro momento foi realizada uma dinâmica sobre o tema para verificar a sedimentação do aprendizado. Participaram da ação 18 alunos do ensino fundamental, sendo 11 meninas (61%) e 7 meninos (39%), com faixa etária de 12 a 14 anos. Constatou-se que a maioria dos alunos não era praticante de qualquer atividade física. Considerações finais: Considerando a experiência prática vivenciada nesta ação educativa as autoras observaram em seus achados que os adolescentes adotaram atualmente um estilo de vida de acordo com seu dia a dia e estão vivendo com hábitos irregulares e comportamentos sedentários que compõem de forma natural a sua rotina social e familiar, o que pode ocasionar em DCV precoce.
Comparação nutricional e enzimática entre indivíduos saudáveis e fenilcetonúricos: revisão sistemática e metanálise
Authors: Gonçalves Lucas Cândido , Cunha Marcos de Oliveira , Barbosa Gabriel de Oliveira , Digues Thiago Alves , Alcantara Raphael Ladislau de , Passos Xisto Sena , Junior Milton Camplesi , Ataídes Fábio Silvestre , Rede Arisneide Kasue Ikeda , Silva Antonio Márcio Teodoro Cordeiro
Published: February 2020

Objetivo: Este estudo objetivou avaliar as diferenças das médias de selênio, coenzima Q10 (CoQ10), status total antioxidante (STA), L-carnitina e glutationa peroxidase (GPx), comparando portadores de fenilcetonúria a indivíduos saudáveis, por meio de uma revisão sistemática e metanálise. Métodos: Para tal pesquisa foram selecionados 24 artigos, nas bases de dados PubMed e LILACS, 15 contribuíram com dados para as análises estatísticas, realizadas com o auxílio do software BioEstat® 5.3. Resultados: Todos os resultados referentes às concentrações séricas, demonstraram redução em fenilcetonúricos quando comparados com indivíduos saudáveis: selênio de 0,5 vez menor; CoQ10 com média de 0,08 vez menor; STA com média das diferenças de 0,15 vez menor; L-carnitina livre com média igual 7,8 vezes menor e GPx com concentração 1 vez menor. Em todas as médias a significância foi evidente, com p<0,0001. Considerações finais: É explícito a necessidade de uma suplementação nutricional, como tratamento coadjuvante a dieta restritiva, com o objetivo de evitar danos às membranas celulares e ao material genético.
Recurrent aggressive multicystic ameloblastoma with hemangiomatous proliferation and giant cells: A perplexed diagnosis
Authors: Routray S. , Mishra S. , Mohanty N. , Panda S. , Panda P.
Published: February 2020

Hemangiomatous ameloblastoma, a very rare variant of ameloblastoma, was originally described as ameloblastoma in which part of the tumor contained spaces filled with blood or large endothelial-lined capillaries. Ameloblastoma, the most commonly affecting a slow-growing, persistent, and locally aggressive neoplasm of epithelial origin, account for a major chunk of all odontogenic tumors. A 43-year-old female reported to our outpatient department with a rare association of multicystic ameloblastoma with unusual hemangiomatous proliferation (both in lining and the stroma) along with giant cells in the lesional tissue. There are <8 cases documented in the literature with the same histologic features and most are in the middle age with the mandibular location.
TỔNG HỢP VẬT LIỆU NANO BẠC VÀ ĐÁNH GIÁ KHẢ NĂNG KHÁNG NẤM PYRICULARIA ORYZAE GÂY BỆNH ĐẠO ÔN TRÊN CÂY LÚA
Authors: Thanh Hải Nguyễn Thị , Mỹ Phương Tôn Nữ , Thu Thủy Nguyễn Thị , Thái Hòa Trần
Published: February 2020

Trong nghiên cứu này, vật liệu nano bạc (AgNPs) được tổng hợp bằng phương pháp khử hóa học với chất khử là natri citrate và chất bảo vệ là alginate. Các thông số ảnh hưởng tới quá trình tổng hợp nano bạc gồm nồng độ natri citrate, nồng độ bạc nitrate, nồng độ alginate và nhiệt độ của hệ phản ứng đã được nghiên cứu. Sự hình thành AgNPs, hình thái và cấu trúc của vật liệu sau khi tổng hợp được phân tích bằng quang phổ hấp thụ phân tử, hiển vi điện tử quét, hiển vi điện tử truyền qua và nhiễu xạ tia X. AgNPs có hiệu lực ức chế cao đối với nấm Pyricularia oryzae gây bệnh đạo ôn trên cây lúa.
NGHIÊN CỨU KHẢ NĂNG KHÁNG VI KHUẨN Vibrio spp. GÂY BỆNH HOẠI TỬ GAN TỤY CẤP (AHPND) TRÊN TÔM CHÂN TRẮNG (Litopenaeus vannamei) CỦA DỊCH CHIẾT TỪ CÂY CHÓ ĐẺ THÂN XANH (Phyllanthus amarus Schum)
Authors: Phương Trần Vinh , Hân Hoàng Thị Ngọc , Long Đặng Thanh , Yến Phạm Thị Hải , Linh Nguyễn Quang
Published: February 2020

Kết quả nghiên cứu nhằm xác định khả năng kháng khuẩn của dịch chiết từ cây chó đẻ thân xanh (Phyllanthus amarus); nồng độ ức chế tối thiểu (MIC) và nồng độ tiêu diệt tối thiểu (MBC) trên 2 chủng vi khuẩn Vibrio parahaemolitycus (K15) và Vibrio sp. (VT33) ở mật độ 106 CFU/mL gây bệnh hoại tử gan tụy cấp (Acute Hepatopancreatic Necrosis Disease –AHPND) còn được gọi là hội chứng tôm chết sớm (Early Mortality Syndrome - EMS) trên tôm chân trắng (Litopenaeus vannamei) nuôi tại Thừa Thiên Huế, kết quả ban đầu ghi nhận: dịch chiết được chiết xuất dạng cao từ cây chó đẻ thân xanh (P. amarus) có khả năng kháng cả 2 chủng Vibrio parahaemolitycus (K15) và Vibrio sp. (VT33) thử nghiệm từ nồng độ 250 đến 1.000 mg/mL, thể hiện ở đường kính vòng kháng khuẩn dao động từ 16,60–21,40 mm đối với chủng Vibrio parahaemolitycus (K15) và từ 17,60 – 23,60 mm đối với Vibrio sp. (VT33). Kết quả cũng xác định hiệu quả của dịch chiết trên 2 chủng Vibrio parahaemolyticus (K15) và Vibrio sp. (VT123) thể hiện giá trị MIC và MBC tương ứng đạt 125 mg/mL và 500 mg/mL; 62,5 và 500 mg/mL.
PHÂN LẬP VÀ SÀNG LỌC CÁC CHỦNG Vibrio parahaemolyticus GÂY BỆNH HOẠI TỬ GAN TỤY CẤP TÍNH TRÊN TÔM THẺ CHÂN TRẮNG NUÔI TẠI PHONG ĐIỀN, THỪA THIÊN HUẾ BẰNG CHỈ THỊ PHÂN TỬ 16S rRNA
Authors: Khanh Nguyễn Văn , Linh Nguyễn Quang , Lan Trần Thúy , Tuyết Nhân Lê Thị , Khánh Vân Trần Quang , Kim Cơ Nguyễn Thị , Dung Trần Quốc
Published: February 2020

Bệnh hoại tử gan tụy cấp tính (AHPND, acute hepatopancreatic necrosis disease) trên tôm thẻ chân trắng là một trong những bệnh gây thiệt hại nghiêm trọng cho nghành nuôi tôm của tỉnh Thừa Thiên Huế nói chung và huyện Phong Điền nói riêng trong những năm gần đây. Bệnh làm cho tôm chết hàng loạt ở giai đoạn 20-45 ngày tuổi (tỷ lệ tôm chết lên đến 100%) trên cả tôm sú và tôm thẻ chân trắng. Tác nhân gây bệnh AHPND là do các chủng vi khuẩn Vibrio có chứa hai gen độc tố PirA và PirB, cùng nằm trên một plasmid. Bằng kỹ thuật PCR với hai cặp mồi đặc hiệu chúng tôi đã xác định được hai chủng Vibrio sp. K5 và Vibrio sp. K21 có mang hai gen độc tố PirA và PirB gây bệnh AHPND trên tôm thẻ chân trắng nuôi tại Phong Điền, Thừa Thiên Huế trong số năm chủng vi khuẩn Vibrio phân lập được từ các mẫu tôm bệnh phẩm. Kết quả phân tích trình tự gen 16S rRNA đã sàng lọc được hai chủng Vibrio sp. K5 và Vibrio sp. K21 thuộc loài Vibrio parahaemolyticus.
PHÂN LẬP, ĐỊNH DANH VÀ KHẢO SÁT MỘT SỐ TÍNH CHẤT CÓ LỢI CỦA VI KHUẨN LACTIC TỪ TÔM CHUA Ở THỊ XÃ GÒ CÔNG, TỈNH TIỀN GIANG
Authors: Tất Trương Quốc
Published: February 2020

Mục tiêu của nghiên cứu này là phân lập, định danh và khảo sát một số đặc tính có lợi của các dòng vi khuẩn lactic từ tôm chua ở thị xã Gò Công, tỉnh Tiền Giang. Từ 4 mẫu tôm chua, đã phân lập được 18 dòng vi khuẩn lactic, khuẩn lạc của chúng có màu trắng sữa hoặc trắng ngà, bìa nguyên hay bìa răng cưa, mô, Gram dương, catalase và oxydase âm tính. Chúng có khả năng sinh acid lactic cao trong môi trường MRS broth có muối ở các nồng độ 0%, 4%, 6%, 8% (1,12 – 2,19 mg/mL trong 24 giờ nuôi). Trong đó, dòng vi khuẩn GK1 và GH5 có khả năng sinh acid lactic cao hơn các dòng còn lại trong môi trường ở 4 nồng độ muối khác nhau. Khảo sát khả năng chịu môi trường khắc nghiệt, dòng vi khuẩn GK1 biểu hiện một số đặc tính probiotic như chịu được pH thấp, dịch dạ dày nhân tạo (pepsin), muối mật. Vì vậy 2 dòng vi khuẩn này đã được định danh, kết quả định danh cho thấy 2 dòng vi khuẩn GK1 và GH5 có mức tương đồng 99% so với Lactobacillus farciminis  và Lactobacillus futsaii nên 2 dòng vi khuẩn này được định danh lần lượt là L. farciminis GK1 và L. futsaii GH5. Việc bổ sung nguồn vi khuẩn khởi động vào quá trình lên men tôm chua giúp rút ngắn thời gian lên men (rút ngắn 37,14% thời gian lên men so với đối chứng), đánh giá cảm quan tôm chua thành phẩm đạt loại khá và đảm bảo các chỉ tiêu vi sinh theo QCVN 8 – 3:2012/BYT.
DO XADREZ À INTELIGÊNCIA ARTIFICIAL: O IMPÉRIO DO DIREITO (FRANCÊS) CONTRA-ATACA
Authors: De Conto Boscatto Muriele
Published: February 2020

O artigo trabalha com o recorte metodológico da inteligência artificial e a sua estruturação à resposta jurídica, ou seja, com o conceito de Direito dos algoritmos em cotejo com o interpretativismo dworkiniano. O debate Hart e Dworkin e a insistente luta deste contra o modelo descritivo de regras da teoria dos fatos sociais deu substrato à discussão e permitiu a identificação inexorável do “conjunto verdade” do robô à citada teoria positivista. O diálogo se desenvolve evidenciando a sucumbência da perspectiva técnica ao paradigma da intersubjetividade, eis que nega o lócus hermenêutico e se subsume às metafísicas clássica e moderna, para a entificação e o assujeitamento da norma jurídica, e não à resposta hermeneuticamente adequada do intérprete responsável pelo empreendimento compreensivo. O contexto francês aparece para amostrar perspectiva legislativa responsável ao trato da questão explorada. O robô é um eximo enxadrista, mas não compreende a cortesia: portanto, não pode enveredar-se à Teoria do Direito e da Decisão Judicial. A metodologia empregada é a fenomenologia hermenêutica.
QUADRO JURÍDICO DE APOIO AOS PEQUENOS EMPREENDIMENTOS: LEI DO MEI, LIMITAÇÕES E POTENCIALIDADES
Authors: Campanha Lucas José , Ramalheiro Geralda Cristina De Freitas , Barboza Ricardo Augusto Bonotto
Published: February 2020

O objetivo foi construir arcabouço teórico sustentador para a análise do processo de implementação de uma política de formalização de microempreendedores. Apresenta-se, uma análise da evolução do instrumento jurídico. Em termos metodológicos, a pesquisa foi apoiada em pesquisa documental, via análise de conteúdo. Contatou-se que houve uma movimentação do estado brasileiro para disciplinar e garantir direitos isonômicos aos pequenos empreendimentos e que, este processo histórico e gradual, a pesar das limitações, apresenta inúmeras vantagens cujos impactos atuam na esfera individual de cada empreendimento e na esfera social, ampliando a atuação do estado e promovendo o bem-estar da população.
Reflexões sobre os determinantes da competitividade da Agroindústria Processadora de Soja no Rio Grande Do Sul
Authors: Rhoden Angélica Cristina , Costa Nilson Luiz , Gellati Elisangela , Brum Argemiro Luis
Published: February 2020

O objetivo do presente artigo foi analisar os determinantes da competitividade da agroindústria gaúcha processadora de soja, com base em suas percepções sobre os determinantes da competitividade sistêmica. O referencial teórico utilizado contemplou as contribuições sobre o Modelo de Competitividade Sistêmica. Os procedimentos empregados para atender aos objetivos da pesquisa contemplam a coleta de dados primária, realizada através de questionários semiestruturados, com questões fechadas e abertas. As técnicas empregadas para o tratamento dos dados foram as medidas de tendência central e de dispersão. Também foram calculados indicadores para sumarizar as respostas dos questionários aplicados para gestores das nove agroindústrias pesquisadas. Os resultados revelaram que os investimentos das processadoras entre 2013 a 2018 foram concentrados em inovações, gestão empresarial e variáveis vinculadas ao processo produtivo. A análise permitiu concluir que os fatores que fundamentam a atuação competitiva das empresas estão baseados na estrutura produtiva e na gestão empresarial.
Penambahan Herba Krokot ( Portulaca oleracea l) pada Pengembangan Siomay Fungsional
Authors: Supriatin Supriatin , Sukainah Andi , Mustarin Amirah
Published: February 2020

Penelitian ini bertujuan untuk mengetahui pengaruh penambahan herba krokot (Portulaca olerace l) terhadap kualitas dan daya terima siomay fungsional yang dihasilkan. Rancangan percobaan yang dilakukan pada penelitian ini adalah Rancangan Acak Lengkap (RAL). Parameter yang diuji adalah kadar air, kadar abu, kadar protein, kadar  lemak, kadar karbohidrat dan β-karoten. Hasil penelitian menunjukkan bahwa siomay krokot yang terbaik dengan penambahan herba krokot ditujukan pada perlakuan penambahan herba krokot 15% lebih disukai panelis dari segi warna, tekstur, rasa, aroma dengan kadar air 48,21%, kadar abu 1,43%, kadar lemak 0,13%, kadar karbohidrat 42,86%, kadar protein 77,43%, dan kadar β-karoten 333 µg/g dan memenuhi syarat mutu (SNI 7756:2013).
Perendaman Telur dalam Larutan Daun Ketapang (Terminalia Cattapa L ) Terhadap Daya Tetas Telur Ikan Mas (Cyprinus carpio L)
Authors: Saenal Saenal , Yanto Subari , Amirah Amirah
Published: February 2020

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh perendaman telur dalam larutan daun ketapang (Terminalia cattapa L) terhadap daya tetas telur ikan mas. Penelitian ini merupakan penelitian eksperiment kuantitatif dengan menggunakan rancangan acak lengkap (RAL) terdiri dari tiga perlakuan. Perlakuan A dengan larutan (1 g/L), perlakuan B (15 g/L), perlakuan C (2 g/L) dan sebagai kontrol tanpa pemberian larutan (Perlakuan K). Percobaan ini dilakukan tiga kali perlakuan sampai didapatkan 12 unit percobaan. Data telah dianalisis menggunakan analisis sidik ragam. Hasil dari penelitian diketahui perlakuan C dengan dosis perendaman larutan daun ketapang 2 g/L yaitu sebesar 94%. Tingginya daya tetas telur ini disebabkan karena adanya kandungan tanin yang terdapat dalam larutan daun ketapang (Terminalia cattapa L) yang memberikan perlindungan bagi telur-telur pada saat perendaman.
Кристаллографический анализ фазовых превращений в данбурите CaSi2B2O8
Authors: Борисов С.В. , Магарилл С.А. , Первухина Н.В.
Published: February 2020

Кристаллографический анализ структур данбурита CaSi2B2O8 — ромбического (Pnma) при нормальном давлении, триклинного (P–1) при давлении 25.4 ГПа и моноклинного (P21/c) при давлении 32.3 ГПа — показал, что в их основе имеется совместная упаковка катионов Са и анионов O, регулярность которой увеличивается с ростом давления. Общий фрагмент структур — конфигурация атомов, связанных плоскостью скользящего отражения, сохраняющаяся для позиций Са и части О, В при вероятной миграции Si по «качельному» механизму (по Н.В. Белову).
Primer registro de anidación de la tángara azul gris (Thraupis episcopus) en Guerrero, México
Authors: Blancas-Calva Epifanio , Castro-Gutiérrez Santiago Baltazar , Contreras-Rodríguez Antonio Isaín
Published: February 2020

La reproducción es un parámetro poblacional útil en el reconocimiento del área de distribución de las especies. Definida el área de distribución stricto sensu como el espacio donde la especie vive e interactúa de forma no efímera con todos los componentes del ecosistema. La tángara azul gris es una especie residente común de la región Neotropical. El área de distribución histórica de la especie en México, con base en registros de la década de 1970, fue en Veracruz. En los últimos 50 años la especie ha experimentado un constante incremento en su área de distribución. Actualmente se le registra en ambas vertientes; de Nuevo León a Yucatán y desde Guerrero hasta Chiapas. Los primeros registros de la tángara azul gris en Guerrero datan del año 2006, presencia que ha sido corroborada, en las planicies costeras del sureste y centro del estado, con registros confiables de los años 2016 y 2018. Sin embargo, se carecía de información sobre aspectos biológico-reproductivos de la especie en Guerrero. En esta comunicación informamos del primer registro de anidación de la tángara azul gris (Thraupis episcopus) en Guerrero, como una evidencia incontrovertible del establecimiento de la especie en el estado.
Teknik Pembelajaran pada Aspek-aspek Pendidikan Islam dalam Surah Luqman Ayat 13-19
Authors: Mahtum Rohiqi , Fikri Ahmad Rijalul
Published: February 2020

Pendidikan adalah usaha sadar untuk mewujudkan suasana belajar dan proses pembelajaran agar peserta didik secara aktif mengembangkan potensi dirinya untuk memiliki kekuatan spiritual keagamaan, pengendalian diri, kepribadian, kecerdasan, akhlak mulia, serta ketrampilan yang diperlukan dirinya, masyarakat, bangsa dan negara. Pendidikan sangatlah dibutuhkan pada masa sekarang ini terutama pendidikan yang islami. Pendidikan yang islami maksudnya pendidikan islam yaitu pendidikan yang mengandung aspek-aspek yang ada pada agama Islam. Karena Islam adalah agama yang rahmah disebabkan karena diturunkan melalui nabi yang rahmah yaitu Nabi Muhammad saw. Aspek-aspek pendidikan Islam haruslah diterapkan pada setiap lembaga pendidikan utamanya pendidikan yang barbasic Islam sehingga nampak nyata prinsip pendidikan yang berlandaskan ajaran Islam.
PENGARUH LINGKUNGAN PESANTREN TERHADAP KEDISIPLINAN SISWA KELAS XII MADRASAH ALIYAH MIFATAHUL HUDA
Authors: Inayati Isna Nurul , Albar Melani , Suwargianto Wiwit , Astuti Linda Yuli
Published: February 2020

Disiplin sekolah merupakan aturan-aturan yang diberlakukan untuk mengatur perilaku siswa di sekolah. Ada sebuah asumsi yang berkembang di masyarakat bahwa siswa yang tinggal di pesantren lebih cenderung melakukan pelanggaran terhadap kedisiplinan di sekolah dibandingkan dengan siswa yang tidak tinggal dipesantren. Hasil observasi awal menunjukkan bahwa siswa yang tinggal dipesantren cenderung lebih sering terlambat sekolah, kerapian dalam penggunaan seragam sekolah tergolong rendah, serta sering tidak menggunakan artibut sekolah yang di wajibkan sekolah. Maka dari itu peneliti mempunyai pandangan bahwa lingkungan pesantren itu sangat berpengaruh terhadap kedisiplinan siswa kelas X Madrasah Aliyah Miftahul Huda. Untuk menguji adanya pengaruh lingkungan pesantren terhadap kedisiplinan siswa kelas X Madrasah Aliyah Miftahul Huda Kepanjen, maka penelitian ini hendak dilakukan.
Penelitian ini dilaksanakan di Madrasah Aliyah Miftahul Huda Mojosari Kepanjen Malang pada tahun ajaran 2017/2018. Peneliti menggunakan pendekatan kuantitatif dengan jenis korelasional, sampel penelitian ini adalah seluruh siswa kelas X Madrasah Aliyah Miftahul Huda dengan jumlah 30 siswa. Teknik pengumpulan data yang digunakan adalah angket, sedangkan dokumentasi dan observasi adalah sebagai pendukung dalam penelitian ini . Data yang sudah terkumpulkan kemudian dianalisis menggunakan korelasi produk moment serta analisis regresi linear sederhana dan kemudian ditarik kesimpulan.
Hasil penelitian menunjukan bahwa Uji Regresi Linear Sederhana diketahui nilai R square sebesar 0,22 menunjukkan bahwa pengaruh lingkungan pesantren terhadap kedisiplinan hanya sebesar 22% sedangkan 78% kedisiplinan siswa dipengaruhi oleh selain lingkungan pesantren. Jadi pengaruh pesantren masih sangat kecil. Sedangkan peneliti menggunakan Uji Korelasi Produk Momentnilai signifikansi sebesar 0,433, hal ini berarti bahwa nilai signifikansi lebih besar dari 0,05 kemudian dari sini dapat diketahui  terdapat korelasi tidak signifikan antara variabel lingkungan pesantren (X) dengan kedisiplinan siswa (Y).Dari sini dapat ditarik kesimpulan bahwasanya lingkungan pesantren (X) sangat kecil pengaruhnya, dan tidak ada pengaruh yang signifikan dengan kedisiplinan siswa (Y) di Madrasah Aliyah Miftahul Huda
THE CHARACTERISTICS OF SEDIMENTATION PATTERN AND MORPHOLOGICAL CHANGE OF SIGELENG RIVER ESTUARY IN RANDUSANGA KULON VILLAGE BREBES DISTRICT
Authors: Barkah Atiyah , Wiyanti Dwi Sri , Laksono Taufik Dwi
Published: February 2020

Sigeleng River Estuary is located in Brebes Regency. The mouth of Sigeleng River Estuary suffering morphological change that caused by the sand spit that close the mouth of river estuary and creating deflection.

The results of  characteristics test of the sediment from the estuary of Sigeleng River shows that the average density is 2.228 kg/l and the average particle diameter (D60) is 0.466 mm. On the other hand the largest result of total suspended solid test of the sediment samples is 1.58 mg/l. According to USDA,  the soil texture in B location is Silt Loam and in A and C location are Sandy Loam. SED2D modeling that performed for 720 hours that assumed as 1 year shows a base elevation change that is 11,79%-30,20%  in the river estuary mouth at the existing condition

Sediment cumulation that occurred around the mouth of the Sigeleng River Estuary within 5 years is 0.007 m - 2,560 m, while the depth of the Sigeleng River Estuary is only -3.00 m. Therefore, a treatment by dredging the sediment aroud the mouth of Sigeleng River Estuary is needed so that the river estuary is not closed.
Perbandingan Ekstrak Jahe Merah (Zingiber Officinale Roscoe. Var. Rubrum), Gingerol dan Shogaol sebagai Anti-Toksoplasma terhadap Parasit Toxoplasma Gondii Secara In-Vitro
Authors: Sa’diah Siti , Anwar Effionora , Jufri Mahdi , Cahyaningsih Umi
Published: February 2020

Metode ekstraksi dan jenis pelarut yang digunakan akan berdampak pada proses penarikan komponen aktif sehingga akan berpengaruh juga pada aktivitasnya. Jahe merah (Zingiber officinale var. Rubrum) merupakan salah satu bahan rempah yang juga berpotensi sebagai tanaman obat. Salah satu khasiat ekstrak jahe merah adalah sebagai anti toksoplasma. Pada penelitian ini telah dilakukan pembuatan ekstrak jahe merah dengan dua jenis metode yaitu maserasi dan sokhletasi masing-masing menggunakan tiga jenis pelarut (etanol 30%, etanol 70% dan etanol 96%) sehingga diperoleh enam jenis ekstrak. Kemudian masing-masing ekstrak ditentukan kadar senyawa pencirinya meliputi 6-gingerol, 8-gingerol, 10-gingerol dan 6-shogaol dengan Kromatografi Cair Kinerja Tinggi (KCKT). Selanjutnya ekstrak diuji aktivitas antitoksoplasma secara in vitro terhadap parasit Toksoplasma gondii pada fase takhizoit yang ditumbuhkan pada sel vero. Penentuan aktivitas antitoksoplasma juga dilakukan pada senyawa murni 6, 8, 10-gingerol dan 6-shogaol serta kontrol positif antibiotik spiramisin. Hasilnya menunjukkan bahwa ekstrak etanol 96% dengan metode maserasi adalah yang paling baik aktivitasnya dan 6-gingerol adalah senyawa penciri yang paling berperan sebagai anti-toksoplasma.
Aktivitas Antioksidan, Antibakteri, dan Toksisitas Ekstrak Kulit Batang Pohon Kesambi (Schleichera oleosa (Lour) Oken)
Authors: Sari Puspita , Sugita Purwantiningsih , Santoso Adi
Published: February 2020

Penelitian ini bertujuan untuk membandingkan aktivitas antioksidan, antibakteri, dan uji toksisitas dari berbagai jenis ekstrak kulit batang pohon kesambi (Schleichera oleosa (Lour)Oken). Tahapan penelitian meliputi proses esktraksi kulit batang kesambi dari kecamatan Mancak Serang dengan teknik maserasi bertingkat menggunakan 3 pelarut : Metanol, n-heksan, dan etil asetat. Ekstrak tersebut kemudian diuji aktivitas antioksidan, antibakteri, dan toksisitasnya. Hasil pengujian antioksidan dengan metode DPPH, antibakteri dengan metode difusi agar, dan uji toksisitas dengan metode BSLT didapat hasil penelitian menunjukkan bahwa ekstrak etil asetat memiliki aktivitas antioksidan (IC50 7,723 ppm) yang lebih baik dibandingkan dengan ekstrak metanol (IC50 7,801 ppm), dan ekstrak n-heksan (IC50 8,568 ppm). Aktivitas antibakteri menunjukkan adanya kemampuan untuk menghambat pertumbuhan bakteri Streptococcus aureus dibandingkan bakteri Escherichia coli pada konsentrasi 10000 ppm, dan hasil uji toksisitas menunjukkan bahwa ekstrak etil asetat memiliki aktivitas yang lebih baik (LC50 305,17 ppm) dibandingkan ekstrak n-heksan (LC50 374,96 ppm) dan ekstrak metanol (LC50 431,26 ppm).
DIREITO SISTÊMICO COMO MÉTODO CONSENSUAL PARA RESOLUÇÃO DE CONFLITOS NO DIREITO DE FAMÍLIA
Authors: Viana Ana Paula Gomes dos Santos , Naves Gabriela Gomes dos Santos
Published: February 2020

A ideia deste artigo é explanar sobre o método consensual de resolução de conflito que tem sido utilizado no Poder Judiciário, qual seja a constelação familiar, trazendo a importância da aplicação desta sistêmica no direito de família. Trata-se de um tema de suma importância em todo o contexto social, porém, a implantação desta sistêmica em âmbito jurídico tem sido importante ante aos resultados já apresentados em outras comarcas. A utilização desta técnica tem como fundamento a Resolução do CNJ, cujo esta, determinou a aplicação de métodos consensuais para a resolução de conflitos. E em concordância com a Resolução, o Juiz do estado da Bahia Dr. Sami Storch, implanta a constelação familiar no âmbito jurídico e dá a denominação de Direito Sistêmico, onde há cerca de 12 anos vem trabalhando com a sistêmica no Tribunal da Bahia, obtendo inúmeros resultados, bem como, vem apresentando a sistêmica através de whorkshops por todo o país, mostrando a necessidade da implantação de novos métodos consensuais para a resolução de conflitos. E mostrando ainda, a importância de trazer para o sistema familiar a harmonia, que é aquilo que muitas vezes as pessoas buscam, porém não sabem como resolver a questão. Como se trata de uma questão ainda em estudos, tendo apenas relatos, e demonstração de resultados já obtidos, não há, portanto, uma discussão doutrinária, sendo assim, são dados baseados em alguns resultados já obtidos.
A JUDICIALIZAÇÃO DA SAÚDE, O ACESSO A MEDICAMENTOS E A RESPONSABILIDADE DOS ENTES FEDERATIVOS
Authors: Lima Jordão Horácio da Silva , Oliveira Maria Geovana Rodrigues de
Published: February 2020

Considerando que o art. 196 da Constituição Federal estabelece que a saúde é um direito de todos e dever do Estado, não se pode olvidar da necessidade de se considerar fatores econômicos para o efetivo cumprimento do direito à saúde. Objetivou-se, na presente investigação, verificar a adequação das políticas públicas brasileiras em relação à efetivação do direito fundamental à proteção e promoção da saúde, e o tensionamento entre o judiciário e os demais poderes da República, no que concerne ao fenômeno da judicialização. Buscou-se, ainda, averiguar os dilemas do pacto federativo brasileiro tendo em vista a relação entre o acesso à justiça e a efetividade de um dos aspectos do direito à saúde: o acesso a medicamentos de alto-custo, numa perspectiva bioética e sanitária, no ambiente Judiciário. A pesquisa baseou-se no método exploratório e em uma revisão (bibliográfica) de artigos e decisões judiciais mais recentes concernentes ao fornecimento judicial de tecnologias sanitárias. Concluiu-se que, nos dias atuais, as decisões judiciais concessivas de medicamentos redundam em uma disfunção na organização das políticas administrativas do setor de saúde, e que as iniciativas em curso para aumentar o acesso a produtos farmacêuticos são insuficientes. Nesse sentido, o Brasil ainda carece de um debate público substancial no tocante ao significado e ao objeto do direito à saúde à luz dos novos avanços médicos.