bluuebunny/crossref_metadata_2025 huggingface dataset:
KEADAAN SOSIAL EKONOMI NELAYAN BAGAN TANCAP DI PANTAI TIMUR PERAIRAN PANGANDARAN, JAWA BARAT
Authors: Astiyani Wahyu Puji
Published: April 2022

This study aims to determine the socio-economic conditions of the fishing families of Bagan on the East Coast of Pangandaran Regency, West Java. This research was conducted in September-November 2019. This study used a descriptive method where the population was 21 respondents from 38 people. Collecting data using interview techniques, observation, questionnaires and documentation. The results showed that the education level of the Bagan fishermen on the east coast of Pangandaran Regency was still relatively low, namely as much as 61.9% with elementary school level education (SD). More than 76% of Bagan fishermen on the east coast of Pangandaran Regency have family dependents where in one family the number of dependents is more than 5 people. Bagan fishermen on the east coast of Pangandaran Regency have an average of 9.74 years of experience as fishermen with 57.14% being full-time fishermen, or do not have other side jobs with low incomes.
Gambogenic acid protects against high glucose-induced damage of renal tubular epithelial cells by inhibiting pyroptosis through regulating the AMPK–TXNIP pathway
Authors: Li Ningxu , Wen Xiuying , Tang Mingjuan , Peng Xiangmei , Sheng Qizhi , Liu Ping
Published: April 2022

Diabetic nephropathy, a chronic inflammatory disease, is characterized by hyperglycemia-stimulated pyroptosis of renal tubular epithelial cells. Gambogic acid, a primary component of gamboge resin, exerts detoxification, antioxidant, anticancer, anti-angiogenesis and anti-inflammatory capacities. However, the nephroprotective effect of gambogic acid on diabetic nephropathy remains unknown. Human kidney (renal) epithelial cell line HK-2 was treated with dextrorotatory-glucose (D-glucose) to establish an in vitro cell model of diabetic nephropathy, followed by incubation with gambogic acid. CCK-8 was designed to detect cell viability. Enzyme-linked-immunosorbent serologic assay (ELISA) was used to detect the levels of inflammation-related factors. Pyroptosis and underlying mechanism were investigated by Western blot assay. High glucose treatment decreased the viability of HK-2 cell line, while gambogic acid incubation restored the reduced cell viability. High glucose-induced increase in the levels of tumor necrosis factor-α (TNF-α), Interleukin (IL)-6, Monocyte chemoattractant protein-1 (MCP-1) and IL-1β were reduced by gambogic acid. The protein expressions of NLR family pyrin domain containing 3 (NLRP3), N-terminal domain of gasdermin D (GSDMD-N), caspase-1, IL-1β and IL-18 were up-regulated in HK-2 cells after high glucose condition, while down-regulated by incubation of gambogic acid. Gambogic acid attenuated high glucose-induced increase of thioredoxin-interacting protein (TXNIP) and phosphorylated 5' adenosine monophosphate-activated protein kinase (p-AMPK) in HK-2 cell line. Gambogenic acid protected renal tubular epithelial cells against high glucose-induced inflammation and pyroptosis through suppression of AMPK–TXNIP pathway, providing a potential strategy for the prevention of diabetic nephropathy.
The relationship between metacognitive skills and the coach's readiness for professional and educational self-development
Authors:   Kuban State University of Physical Education, Sport and Tourism, Krasnodar, Russia, Romashko Y. S. , Gorskaya G. B. ,   Kuban State University of Physical Education, Sport and Tourism, Krasnodar, Russia
Published: April 2022

The purpose of our study is to identify the relationship of metacognitive skills indicators with the components of professional self-development of coaches. The data were gathered via online survey. The study involved coaches (n = 53) aged 22 to 60 years in various sports, with a professional experience of 1 to 34 years. We are used the questionnaire "Diagnostics of the level of partial readiness for professional-pedagogical self-development" and the questionnaire "Reflexive skills (metacognitive level)" by E.V. Savchenko, methods of mathematical statistics (Spearman's correlation coefficient). According to the results of the study, a relationship was revealed between the general level of development of metacognitive skills and all components of the coach's readiness for professional self-development. According to the results of the study, interrelations were revealed with all components of the coach's readiness for professional self-development and such parameters of metacognitive skills to organize the problem-solving process, to regulate your own emotional states, to monitor mental activity, to form probabilistic problem-solving models.
The impact of sports on the development of resilience of adolescents
Authors:   Ural Federal University, Yekaterinburg, Russia, Rogaleva L. N. , Shtokolov V. S. ,   Ural Federal University, Yekaterinburg, Russia, Shurmanov E. A. ,   Ural Federal University, Yekaterinburg, Russia, Dubinkina Yu. A. ,   Ural Federal University, Yekaterinburg, Russia
Published: April 2022

The article examines the influence of sports on the development of the resilience of adolescents as one of the adaptive resources of the individual to stressful situations. The scientific work provides a methodological justification for the impact of different types of activity on the formation of key components of resilience: engagement, self-control, risk taking. The organization of the study was to compare the indicators and the level of resilience of adolescents included in different social groups: the first group – the student athletes that are engaged in sports schools, the second group – the students of specialized schools for intellectually gifted students, the third one- the students of secondary schools. The study proved that the resilience of adolescents engaged in sports is significantly higher than that of adolescents of secondary schools who are not engaged in sports. But at the same time, the resilience of intellectually gifted adolescents has no significant differences compared to adolescent athletes. The results revealed the most significant relationship between such indicators of adolescent resilience as engagement and risk-taking. Further research may be related to the study of personal characteristics that are most associated with the resilience of adolescents, ensuring their ability to overcome stress factors from the external and internal environment.
Erken Tanıda “Ektopia Kordis” Yönetimi
Authors: MUTLU Ahmet Emin
Published: April 2022

Giriş: Ektopia kordis (EK), 0.5-1/100.000 sıklıkta nadir görülen, kalbin tamamının veya bir kısmının toraks dışında bulunması ile karakterize, bir konjenital anomalidir. Postnatal dönemde prognozları kötü olduğu için bu tür vakaların viabilite öncesi tespit edilmesi durumunda terminasyonu uygun görünmektedir.

Gereç ve Yöntemler: Bu çalışmaya, 2018-2021 yılları arasında kliniğimizde EK tanısı almış 5 hasta dahil edilmiştir. Çalışmaya dahil edilen tüm hastalarda terminasyon sırasında uygulanan tedaviler, sonuçları ve komplikasyon olup olmadığı incelendi.

Bulgular: Beş olguluk seride hastaların genç yaşta olduğu ve genellikle ilk gebelikleri olduğu görüldü. Hastaların hepsinde yapılan obstetrik ultrasonografi inceleme sonucunda kistik higromaya sahip nuchal translusensi artışı mevcuttu. Misoprostol uygulanması sonucu 48 saat içinde yanıt alındı ve abortuslar gerçekleşti.

Sonuç: Prenatal erken dönemde tanı konulan EK olgularında gebelik sonlandırılması anne sağlığı açısından en uygun yaklaşım olarak görünmektedir. Sonlandırılmayan olgularda ise multidisipliner yaklaşım önem arz etmektedir.
Recognizing the rights of nature in Colombia : the Atrato river case.
Authors: Vargas Chaves Iván , Rodríguez Gloria Amparo , Cumbe Figueroa Alexandra , Mora Garzón Sandra Estefanía
Published: April 2022

This article studies the recognition of Río Atrato as a subject of rights through Judgment T-622-16 of the Constitutional Court, in a case without precedent in Colombian Law. To contextualize this jurisprudential milestone, the authors argue that the current regulations failed to protect the biodiversity and related rights of the inhabitants of the areas near the Atrato River. The methodology involved an analysis of the jurisprudential line of the judgments that preceded the case analyzed, as well as the study of theoretical postulates and current environmental regulations from an analytical-deductive approach. As results, the authors present the first jurisprudential line of the Río Atrato judgment, supported by their own reflections that demonstrate the birth of a new stage of environmental law in Colombia.
El daño ambiental y otras externalidades negativas del cultivo de hoja de coca en la era del Posacuerdo
Authors: Leguizamón Arias Wilmer Yesid , Silva Ruiz Andrea , Ramírez Hernández Natalia Elisa
Published: April 2022

El problema polisémico de los cultivos de uso ilícito, particularmente el relacionado con la hoja de coca, es abordado desde el estudio de algunas de las externalidades negativas derivadas de la producción de hoja de coca respecto al medio ambiente y la economía de las comunidades que se dedican a su producción, las cuales han tendido a agudizarse en el posacuerdo. En este sentido, se presenta un análisis que articula las narrativas económicas y jurídicas a través del análisis económico del derecho, para tener una aproximación teórica y empírica a los eventuales efectos que puede producir determinada política, decisión o regulación jurídica sobre este tipo de economías ilícitas.
Gobernanza ambiental y transformación social en Colombia
Authors: Pérez Niño Walter
Published: April 2022

El artículo, a partir de un análisis sociojurídico, examina la incidencia de factores como modelo económico, posconflicto, extractivismo y violencia armada en los conflictos ambientales. Se concluye que herramientas como la gobernanza, en un marco de cambio social y democracia participativa, puede ser una alternativa para la solución de las complejidades de la gestión ambiental.
En defensa del litigio colectivo en moralidad administrativa en Colombia: acciones populares y el conflicto de intereses
Authors: Páez Murcia Ángela María , Barreto Moreno Antonio Alejandro
Published: April 2022

Las acciones populares son el mecanismo de litigio colectivo que la Constitución Política Colombiana prevé para proteger derechos e intereses, entre ellos la moralidad administrativa. Para  este evento, los ciudadanos cuentan con la posibilidad de demandar a las autoridades públicas y privadas encasos donde la ética pública ha sido amenazada o vulnerada, con el objeto de prevenir daños o restaurar derechos vulnerados. Recientes desarrolloslegislativos y jurisprudenciales, de manera equivocada, han debilitado las acciones populares en Colombia y han reducido al mínimo el posible rol del derecho colectivo a la moralidad administrativa. Este artículo analiza la dimensión preventiva de la acción popular reflejada en el daño contingentey su relación con la protección de la moralidad administrativa en casos de conflicto de intereses. Se concluye que el debilitamiento de las accionespopulares es desafortunado y que la acción popular por moralidad administrativa es un mecanismo idóneo para precaver conflictos de intereses y por tanto para fortalecer la gestión administrativa y servir de apoyo a la lucha anticorrupción.
Los “daños punitivos” y su incorporación al derecho peruano: reflexión acerca de su utilidad en procesos por daños masivos
Authors: Alcántara Francia Olga Alejandra
Published: April 2022

Objetivo. Plantear una reflexión sobre la incorporación al derecho de consumo peruano de la figura anglosajona de los “daños punitivos” con la finalidadde eliminar los casos en los que la conducta del infractor expresada en indiferencia, desinterés, etc. frente a la víctima, no sea castigada y pueda, incluso constituir una actividad redituable. Metodología. Hermenéuticosintética para la caracterización de los supuestos de pena privada, sanciones administrativas y mandatos. Aplicación del método comparado en la evaluación de su implementación en el fuero jurisdiccional o en sede administrativasancionadora. Resultados. Su adopción a través del arbitraje de consumo para los supuestos de protección de intereses y en los procesos judiciales de tutela de intereses difusos puede generar efectos positivos en el mercado. Conclusiones. Desincentivo de conductas reprobables derivadas de un daño masivo.
La valoración de las pruebas de ADN por los jueces de familia en los procesos de investigación de la filiación: El caso colombiano
Authors: Muñoz Aristizábal Manuela Vanesa , Alvarán Márquez María José , Cárdenas Gómez Olga Carolina , Arcila Morales Laura Manuela
Published: April 2022

La prueba de ADN determina, actualmente, la decisión que el juez debe tomar en los procesos de filiación, salvo contadas excepciones. El papel del juez pareciera limitarse a verificar el resultado probabilístico de la misma para determinar quién es padre/madre. Este artículo busca analizar si el papel que los jueces están llamados a desempeñar al momento de valorar la prueba coincide en la legislación, la jurisprudencia y la doctrina. A partir de una revisión documental, se evidenció una tensión entre ellas frente a la valoración de la prueba y el rol que el juez está llamado a desempeñar. Dicha tensión sugiere la necesidad de examinar la importancia que se reconoce a esta prueba, porque el juez no puede ser relevado de su función de valorar las pruebas para tomar una decisión.
[RETRACTED] EAGLE HEMP CBD GUMMIES – (2022 REVIEW) SHOCKING SIDE EFFECTS & IS IT REALLY TRUSTED OR WORKS? v1
Authors: not provided PeriosNeni
Published: April 2022

[RETRACTED]

Eagle Hemp CBD Gummies
Configurable Test System for RTOS of BAGET Family
Authors:   Federal State Institution Scientific Research Institute for System Analysis of the Russian Academy of Sciences (SRISA RAS), Moscow, 117218, Russian Federation, Godunov A. N. , Khomenkov I. I. ,   Federal State Institution Scientific Research Institute for System Analysis of the Russian Academy of Sciences (SRISA RAS), Moscow, 117218, Russian Federation, Shchepkov V. G. ,   Federal State Institution Scientific Research Institute for System Analysis of the Russian Academy of Sciences (SRISA RAS), Moscow, 117218, Russian Federation, Khoroshilov А. V. ,   Ivannikov Institute for System Programming of the Russian Academy of Sciences, Moscow, 109004, Russian Federation
Published: April 2022

The article describes a test system designed for verification of the real-time operating system BAGET Family for embedded systems, developed and used at the Scientific Research Institute for System Analysis of the Russian Academy of Sciences (SRISA RAS). This Unix-like operating system is based on the POSIX and ARINC-653 pro­gramming standards. Of course, there is specialized software for automating testing of Unix-like operating systems, for example, Avocado, LAVA, Linux Test Project, Linux Distribution Checker, Open POSIX Test Suite, UnixBench, etc. But the use of such ready-made software systems is not always convenient since they either contain only highly specialized test suites, support only specific hardware, or do not contain a flexible configuration system. Therefore, In SRISA RAS, its own original test system was developed. The task was to create a convenient testing tool for both software testers and programmers. Many years of experience in utilizing the test system has shown the effectiveness of its use to improve the quality of software products, reduction of time spent on testing and analysis of results, maximum automation of software testing process, speed up the process of developing new software versions, as well as simplify the process of debugging, finding and fixing errors by software developers.
Performance Analysis of Three Levels Three Switches Vienna-Type Rectifier Based on Direct Power Control
Authors: ÇELİK Doğan
Published: April 2022

The Vienna-type rectifier is broadly employed in various implementations thanks to realizable three-level operation, simple structure and controllable DC-link voltage. This paper proposes an adaptive proportional integral (PI) with anti-windup based direct power control (DPC) to improve dynamic response during load change, DC-link voltage step change and start up and to reduce current tracking errors. An adaptive PI with anti-windup DC-link voltage control is utilized to enhance dynamic response of the DC-link voltage and the instantaneous power because the PI regulator affected by the load change and system parameter variations. The PI based conventional power control is used to indicate the availability and accuracy of the proposed control strategy. The proposed control strategy performs outstanding performance and copes with vigorous disturbances in contrast to the conventional strategy. A detailed theoretical analysis of the proposed approach has been performed. Extensive case studies carried out by PSIM software are performed to validate the excellent behavior of the proposed control strategy.
Does aggregating results of AI system for mammography with ML meta-model improve quality of malignancy detection?
Authors: Nikitin E. D.
Published: April 2022

.
Forecasting the incidence of COVID-19 in Moscow: comparison of time series models
Authors: Solov’yev A. V. , Kodenko M. R. , Reshetnikov R. V. , Sukhikh T. D. , Mukhortova A. N. , Blokhin I. A. , Gonchar A. P. , Leonov D. V. , Abramova I. V. , Omelyanskaya O. V.
Published: April 2022

.
Magnetic resonance imaging for aortic wall stiffness
Authors: Bril K. R. , Khovrin V. V.
Published: April 2022

.
Application of radiomics and morphometric analysis in estimation of collateral flow based on CTA of ischemic stroke patients
Authors: Zagriazkina T. A. , Dolotova D. D. , Blagosklonova E. R. , Arkhipov I. V. , Ramazanov G. R. , Gavrilov A. V.
Published: April 2022

.
Determination of the diagnostic efficiency of contrast-enhanced ultrasound in the diagnosis of liver metastases of colorectal cancer
Authors: Kozubova K. V. , Busko E. A. , Bagnenko S. S. , Kostromina E. V. , Kadyrleev R. A. , Kurganskaya I. Kh. , Shevkunov L. N.
Published: April 2022

ABSTRACT
Artificial intelligence for bone mineral density assessment: general population data
Authors: Shelepa A. A. , Petraikin A. V. , Artyukova Z. R. , Abuladze L. R. , Kudryavtsev N. D. , Ahmad E. S. , Semenov D. S. , Zakharov A. A. , Belyaev M. G.
Published: April 2022

.
Impact of the COVID-19 pandemic on the work of urological departments
Authors: Kulchavenya Ekaterina V. , Kholtobin Denis P. , Telina Elena V.
Published: April 2022

BACKGROUND: The pandemic of a new coronavirus infection has had a significant impact on the work of the entire medical service, including urological departments.
AIM: to assess the impact of the COVID-19 pandemic on the work of urological departments in private and public medical institutions.
MATERIALS AND METHODS: We assessed the impact of the restrictions imposed by the pandemic on the work of the urology department of a private clinic (MC Avicenna, Novosibirsk) and the urogenital department of the Novosibirsk Research Institute of Tuberculosis for 2019 and 2020. We assessed the change in the range of surgical interventions, as well as the structure visits to the urologist.
RESULTS: The urogenital department of the Novosibirsk Research Institute of Tuberculosis in March 2020 was redesigned into an observational one. The Avicenna Medical Center also established the procedure for anti-epidemic measures, which made it possible not only not to reduce, but in a number of positions to increase the volume of surgical care provided.
CONCLUSION: Thus, thanks to anti-epidemic measures: separation of flows, introduction of mandatory testing of patients, early detection of patients and carriers among employees, mask regimen, opening of an observational department, single rooms, lack of contact between patients, short stays, it was possible to prevent an outbreak of infection among patients and staff. Both in the municipal and private urological clinics, well-organized work did not allow the negative impact of the pandemic to manifest itself.
Sürdürülebilirlik İletişimi ve Sürdürülebilirlik Kavramı: Türkiye Bankacılık Sektörü Web Sitesi ve Sürdürülebilirlik Raporları Örneğinde Bir Analiz
Authors: DEMİRCİ Kenan
Published: April 2022

Sürdürülebilirlik kavramı, kurumsal sosyal sorumluluğa (KSS) benzer biçimde, çevresel, toplumsal
ve ekonomik problemlere ilişkin belirli çözüm yollarına odaklanmaktadır. Ne var ki sürdürülebilirlik
kavramı, KSS’nin pek çok bakımdan genişletilmiş bir hali olarak nitelendirilebilir. Sürdürülebilirlik anlayışı
içerisinde firmalar tüm faaliyet ve toplumla ilişkilerini, sürdürülebilir bir gelişme için yeniden tanımlamak
zorundadır. Sürdürülebilirliğin bu geniş anlamı, toplumsal yaşam içerisindeki iletişim olanaklarını da etkin
kullanmasını gerektirmektedir. Çünkü farklı unsurlarla iletişim kurma konusunda gösterilecek başarı,
aslında sürdürülebilirliğin pek çok öğeyi kapsamasını da mümkün kılacaktır. Bu sebeple sürdürülebilirlik
iletişimi önemli bir kavram olarak değerlendirilmelidir. İşte bu çalışma sürdürülebilirlik iletişiminin
önemli iki aracı olan web siteleri ve sürdürülebilirlik raporlarında, sürdürülebilirlik kavramının yer alma
biçimlerine ilişkin bir analiz yapmayı amaçlamaktadır. Bu kapsamda çalışmada Türkiye’de faaliyet gösteren
özel ve kamu sermayeli toplam 5 bankanın web siteleri ve sürdürülebilirlik raporları örnek olay tekniği
kapsamında, nitel bir analiz yoluyla çözümlenmiştir. Sonuçta bankaların sürdürülebilirlik kavramını
tanımlama ve ona ilişkin çaba göstermekte önemli adımlar attıkları ancak sürece toplumsal dinamikleri
dâhil edecek araçları geliştirmekte kısmen yetersiz kaldıkları ortaya konulmuştur.
THE ROLE OF VISUAL ART IN FACING THE CORONA PANDEMIC
Authors: Alashari Duaa Mohammed
Published: April 2022

Art is constantly inspired by what happens in its social and cultural context. The arts cannot be separated from life and the significant events in the world, whether it is a war, a natural disaster, or the spread of a disease an epidemic. Today, the whole world is witnessing the Coronavirus (Covid-19) pandemic, one of the worst in human history. The current scene has taken hold of artwork and the visual arts. The spread of the virus has inspired many artists to produce paintings, posters and artwork. This study aims to reveal the role and importance of Arab artists regarding the message they present regarding the situation at hand. In this study, the qualitative data was amassed as part of the methodology. The qualitative descriptive method and the case study approach are the primary approaches for the data collection. The results section focuses on the answers obtained from Arab artists through their artwork. It is held via a virtual exhibition. The discussion section focuses on a detailed analysis of the paintings. The study results concluded that art is a kind of documentation of all of the events that happen to humans. Art is a record of historical events, so it is a bright spot in times of crisis and darkness. Through these paintings, Arab artists have provided a light to those who feel gloomy in these difficult times, indicating that those in the Arab world focus on the unity of place, language and religion. Therefore, this artistic movement moves between all its countries so that no matter how harsh the situation, people will remain unified.
SEMIOTIKA FISKE TERHADAP IDEOLOGI PATRIOTISME FILM "GUNDALA"
Authors: Pratama Adhitiya Prasta
Published: April 2022

This writing aims to reveal the ideology of patriotism in the film Gundala. Namely, when today's film can be reached as a social practice and a medium of mass communication. The problem that is focused on is understanding the signs, meanings, and codes contained in the film's scenes. This paper also describes the history of film in Indonesia and its practice. In order to explore the study of signs and codes in films, this paper uses John Fiske's semiotic unit analysis, namely through the stages of reality, representation, and ideology. The data obtained through search searches, which are sourced from Google and Telegram, and analyzed descriptively qualitatively. This writing concludes that today's film can deconstruct the unity of meaning, symbol, and code in exposing its naturalness as an ideological construction.
KREASI MOTIF BATIK DENGAN TEKNIK PRINTING KHAS JOMBANGAN DARI INSPIRASI TOPENG JATIDUWUR
Authors: Sakinah Anisa Luh , Sidyawati Lisa , Ratnawati Ike
Published: April 2022

Abstrak: Kesenian Wayang Topeng Jatiduwur merupakan peninggalan Majapahit yang hidup dan berkembang ratusan tahun di desa Jatiduwur sebagai kesenian khas Jombang. Tetapi masih banyak dari masyarakat tidak mengetahui keberadaan Topeng Jatiduwur yang memiliki keunikan bentuk visual Topeng, warna, ornament, pertunjukan dan nilai sejarahnya. Tujuan penciptaan ini adalah mendeskripsikan ide konsep motif batik inspirasi Topeng Jatiduwur Jombang, mendeskripsikan proses kreatif motif kain batik dari tokoh Triloka dan upaya pelestarian Topeng Jatiduwur melalui motif batik. Metode yang digunakan adalah metode kreatif terdiri dari beberapa tahap; merumuskan kreasi ide motif batik inspirasi Topeng Jatiduwur Jombang, eksplorasi ide konsep, eksplorasi desain dan teknik, proses kreatif mewujudkan motif batik, hasil kreatif motif batik, dan analisis hasil kreatif. Hasil kreatif  penciptaan berupa enam kain motif batik dengan teknik digital printing diharapkan memberikan efektifitas proses produksi kain batik skala besar, dan nantinya kain dapat digunakan sebagai bahan sandang dengan judul karya sebagai berikut; Jadur Darana, Jadur Prasasta, Jadur Wahya, Jadur Danurweda, Jadur Jasayasa, dan Jadur Lembahmana. Kreasi motif batik bertema Wayang Topeng Jatiduwur ini, sebagai upaya pelestarian kesenian dan pemajuan kebudayaan daerah Jombang. Kata kunci: Motif Batik, Topeng Jatiduwur, Printing, Jombang
Development of UKBM Based on EPUB (Human Digestive System)
Authors: Memiasih Novela , Sari Murni Sapta , Prasetyo Triastono Imam , Sumberartha I Wayan
Published: April 2022

In this globalization era, information is very easy to obtain, therefore critical thinking skills are important for students to have because they can train students to filter the information obtained to solve a problem. The purpose of this research is to produce a product in the form of UKBM based on ePUB on digestive system topic to improve critical thinking skills and cognitive learning outcomes of students who have been tested for validity, practicality and effectiveness. The development model used in this study is the ADDIE development model. The study was conducted at SMA Negeri 5 Malang with the research sample being students of class XI. Research data in the form of the results of the validation of media experts, topic experts, assessment experts, field practitioners, student responses, pretest and posttest results of students. The results showed that the average percentage of validated ratings of media experts, topic experts, assessment experts, field practitioners were 96.74 percent, 100 percent, 100 percent, and 94.23 percent, all of which were in the very valid category. The practicality test value is 92.53 percent which means it is very practical, the value of the effectiveness test is 0.8 which means it is classified as very effective, the results of students critical thinking skills are 82.16 which means it is classified as very critical, and the cognitive learning outcomes of students 93.42 which means it is classified as high. Based on the results of the study it can be concluded that the development of UKBM based on ePUB can improve critical thinking skills and students cognitive learning outcomes.
TÜRKİYE'DE POLİTİK İSTİKRAR VE EKONOMİK BÜYÜME İLİŞKİSİ
Authors: ERDOĞAN Sinan , AKALİN Güray
Published: April 2022

Ekonomik büyüme literatüründe, ülkeler arası büyüme farklılıklarının açıklanmasında kurumsal faktörler üzerinde fazlaca durulmaktadır. Bu kurumsal faktörlerden bir tanesi de ülkelerin yaygın düşünce-davranış alışkanlıklarını güçlü bir şekilde yansıtan politik istikrardır. Zira, politik istikrar hem gelişmiş hem de gelişmekte olan ülkelerde iktisadi faaliyetlerin sürdürülebilir kılınması adına oldukça önemlidir. Bu çalışmanın temel amacı Türkiye’de politik istikrar ve ekonomik büyüme ilişkisini 1984-2017 dönemi için zaman serisi analizi yöntemleriyle araştırmaktır. Çalışmadan elde edilen bulgular şöyle sıralanabilir; (a) analizde kullanılan değişkenler birim kök süreci sergilemekteyken, birinci sıra farkları alındığında ise durağan hale gelmektedir, (b) eşbütünleşme testi sonuçlarına göre değişkenler arasında uzun dönemli bir ilişki vardır, (c) uzun dönemli katsayı tahminine göre politik istikrar, yatırım ve tüketim harcamaları iktisadi büyümeyi pozitif etkilerken, kamu tüketim harcamaları negatif etkilemektedir. Bu bağlamda Türkiye ekonomisinde politik istikrarın sürdürülebilir kılınması yönünde alınacak tedbirler ve uygulanacak politikalar, iktisadi gelişme sürecini olumlu etkileyecektir.
EKONOMİK POLİTİKA BELİRSİZLİĞİ VE BORSA İLİŞKİSİ: G7 VE BRIC ÜLKELERİ ÖRNEĞİ
Authors: GÜRSOY Samet , ZEREN Feyyaz
Published: April 2022

Bugün dünya üzerinde işlem yapılan tüm piyasalar için risk ve belirsizlik büyük önem arz etmektedir. Özellikle finansal piyasaların en aktif pazarları olan ülke borsalarında bu durum daha belirgin olarak görülebilmektedir. Hatta dünyanın önde gelen ülke borsalarında gerçekleşen ekonomik, politik, finansal belirsizliklerin birçok ülke borsalarında getiri kaybına sebep olmaktadır. Bu çalışmada ise seçili gelişmiş ve gelişmekte olan ülkelerde))))) bu durum araştırılmak istenmiştir. Buna bağlı olarak Ocak 2015-Kasım 2020 dönemleri arasında G7 ve BRIC ülkelerinde her ülke için hesaplanan ekonomik politik belirsizlik endeksi (EPU) ile ülkelerin borsaları arasında bir ilişkinin varlığı sorgulanmıştır. Konya panel nedensellik testi kullanılarak yapılan analizler neticesinde, panellerin genelinde EPU’dan borsalara doğru tek yönlü nedensellik olduğu görülmüştür. Elde edilen sonuçlar ülkeler bazında değerlendirildiğinde İngiltere, Amerika ve Brezilya için EPU endeksinden Borsalara doğru tek yönlü bir nedensellik gerçekleşirken, yalnızca Almanya için iki yönlü bir nedenselliğin varlığı tespit edilmiştir. Bunun dışından diğer ülkelerde herhangi bir nedensellik bulgusuna rastlanmamıştır.
THE EFFECT OF IN-GAME PRODUCT PLACEMENT ON ATTITUDE TOWARDS IN-GAME ADVERTISEMENTS AND IN-GAME PURCHASE INTENTION: A STUDY ON YOUNG CONSUMERS
Authors: AKHAN Can Efecan , ÖZDEMİR Erkan
Published: April 2022

Brands and advertisers constantly seek new ways to target audiences shifting towards the digital world and media digitalization who search for new ways to reach and persuade their audiences. The game industry is one of the most affected sectors by those rapid developments. Online games are indispensable entertainment tools of the technology age. As a result, businesses have begun to devote a significant portion of their advertising budgets to in-game advertising campaigns and applications. This study aims to reveal the effect of in-game product placement on young consumers' attitudes towards in-game advertisements and attitudes' effect on their purchase intention. The study was conducted on undergraduate students, and a convenience sampling method was used. As a result, it was found that in-game product placement practices had a negative effect on the attitude towards in-game advertisements. On the other hand, the attitude towards the advertisement had a significant and positive effect on the purchase intention. Men's in-game product placement practices negatively affect the attitude towards in-game advertisements. In contrast, no significant effect was found for women. When the differences between these effect levels were examined, a significant difference was found between the path coefficients according to gender.
TÜRKİYE’DE BÖLGESEL İNOVASYON ETKİNLİĞİNİN DEĞERLENDİRİLMESİ: DÜZEY 2 BÖLGELERİNE YÖNELİK AMPİRİK BİR ANALİZ
Authors: DAĞLI İbrahim
Published: April 2022

Bu çalışmanın amacı, Türkiye’de bölgesel seviyede inovasyon etkinliğinin tespiti ve etkin bölgelerin performans sıralamasının ortaya konulmasıdır. Yöntem olarak veri zarflama analizinin çıktı odaklı BCC ve Süper Etkinlik Modeli kullanılmıştır. Analiz için bölgesel inovasyon ölçümüne yönelik üç girdi (Ar-Ge Harcaması, Ar-Ge İnsan Kaynağı, Yüksek Öğrenim Kaynağı) ve üç çıktı (İleri Teknoloji İhracatı, Patent, Marka) değişkeninden yararlanılmıştır. Araştırmanın zaman boyutu olarak tüm değişkenlerin verilerine ulaşılabilen en güncel yıl olan 2019 yılı esas alınmıştır. Analiz sonucunda 26 adet bölgeden oluşan TR Düzey 2 bölgelerinden 10 tanesi bölgesel inovasyon açısından etkin bölgeler olarak tespit edilmiştir. Etkin olan bu bölgelerin süper etkinlik skorlarına göre performans sıralaması TR10, TRC1, TR72, TR83, TR41, TR22, TR33, TR63, TRC2 ve TRC3 bölgeleri olarak tespit edilmiştir. Etkin olmayan bölgelerin etkinliğe ulaşabilmesi için referans birimler ve hedef değerlere çalışma içeriğinde yer verilmiştir. Bu çalışma, Türkiye için 26 bölge üzerinde (TR Düzey 2) bölgesel seviyede bir inovasyon etkinliği tespiti ve kıyaslaması yapması açısından literatürdeki diğer çalışmalardan farklıdır. Çalışmanın zaman boyutu olarak seçilen 2019 yılı ise literatüre oldukça güncel bir katkı sağlaması açısından önemlidir. Bölgeler arasında inovasyon etkinliğinin tespit edilmesinin yanı sıra süper etkinlik skorları ile bölgeler arasında bir performans sıralaması yapılması çalışmanın bir diğer önemli katkısıdır.
Pemantauan Suhu Kelembaban dan Tekanan Udara Terpusat pada Ruang Operasi Menggunakan Aplikasi Blynk
Authors: Nashir Muhammad Sulthon , Kartika Wisnu , Wibowo Susilo Ari
Published: April 2022

Saat ini dunia sedang mengalami sebuah perubahan besar terkait dengan perkembangan dan kemajuan teknologi. Salah satu yang menjadi tolak ukur kemajuan teknologi dalam bidang kesehatan adalah penemuan dan penciptaan alat-alat medis yang berkembang sedemikian pesat baik yang berhubungan dengan elektronik, mekanik maupun gabungan dari keduanya. Pada umumnya alat untuk memantau baik suhu ruangan, kelembaban dan tekanan ruangan dilakukan di ruangan yang akan dipantau. Oleh sebab itu untuk mempermudah dalam melakukan pemantauan pada ruangan operasi maka dirancang sebuah alat pemantauan suhu, kelembaban dan tekanan udara terpusat pada ruang operasi menggunakan aplikasi Blynk. Perancangan alat ini menggunakan beberapa komponen inti yaitu sensor DHT11, sensor BMP280 dan NodeMCU ESP8266, ESP-01 serta Arduino Mega yang akan terhubung dengan wifi. Hasil pengukuran dari tiap-tiap sensor ditampilkan ke sebuah aplikasi smartphone. Aplikasi yang telah diprogramkan dan aplikasi tersebut dapat dibuka menggunakan aplikasi. Aplikasi Blynk yang telah tersedia di Smartphone, serta dapat ditampilkan pada layar LCD.
Peptic ulcer disease in school children aged 2-11 years in Southeast Nigeria
Authors: Umegbolu Emmanuel I.
Published: April 2022

Background: A peptic ulcer is a sore on the inner lining of the stomach or duodenum, caused mainly by non-steroidal anti-inflammatory drugs and Helicobacter pylori infection. In childhood, peptic ulcer disease (PUD) is an uncommon disease, with an estimated frequency of 1 case in 2, 500 hospital admissions in the United States. Data for developing countries, including Nigeria, are scarce, although peptic ulceration is being increasingly recognized in children in the developing world now. For this reason, this study was designed to investigate PUD in school children in Southeast Nigeria.Methods: 264 children, aged 2-11 years, who attended Cottage Hospital Inyi in 2020 with complaints of abdominal pain were investigated for PUD with stool antigen test. Data collected for a period of one year were analysed as proportions and Chi square, using MaxStat (version 3.60) statistical software. P≤0.05 was considered significant.Results: The prevalence of PUD was 16%; 8.3% in females and 7.6% in males. In the 2-6 years age group prevalence was 7%, while in the 7-11 years age group it was 9%. Association between sex and prevalence of PUD was not significant (p=0.62), but very significant for that with age (p=0.0003).Conclusions: Prevalence of PUD was 16%. This increased with age (7% in the 2-6 years age group and 9% in the 7-11 years group). To address the rising prevalence of PUD in these children, there is need to monitor their feeding habits in school, besides teaching them the importance of personal hygiene.
Comparison of predictive values of Mannheim peritonitis index, acute physiology and chronic health evaluation-II and Portsmouth-POSSUM scoring systems for prognosis of mortality in patients with perforation peritonitis
Authors: Kumar Lokesh , Singh Sunita , Pratap Dhirendra , Singh Krishna K. , Nayak Shubham , Kumar Shailendra , Tripathi Utkarsh
Published: April 2022

Background: Perforation peritonitis has emerged as one of the very common cause of surgical emergencies, particularly in developing countries like India. If left untreated for long due to improper prognosis or late diagnosis, perforation peritonitis may prove potentially fatal with a high mortality and morbidity rate. Scoring systems like APACHE-II (acute physiology and chronic health evaluation), p-POSSUM (Portsmouth-POSSUM) and MPI (Mannheim peritonitis index) may serve as simple, critical, and efficient prognostic tools in predicting the mortality in patients with perforation peritonitis. Thus, the aim of the current investigation was to examine the usefulness and accuracy of these scoring systems for predicting the mortality rate in perforation peritonitis.Methods: Current study was a prospective observational comparative study conducted at department of general surgery, KK Hospital, Lucknow. Detailed clinical and lab investigations of the participating patients were done and their demographic details were documented. Using history, clinical examination and lab values p-POSSUM, APACHE-II and MPI scores were calculated. Scores of each scoring system were statistically analyzed in prognosticating the mortality rate.Results: Mean age of the participating patients was 41.24±19.32 years. Abdominal pain and vomiting were observed as the most common symptoms in majority of patients.  No mortality was observed in patients with ≤20 MPI score, ≤20 APACH-II scores and ≤55 p-POSSUM score. Whereas mortality rate was observed to be 21.53% in patients with >20 MPI score, 82% in >20 APACH-II scores and 78% in >55 p-POSSUM score.Conclusions: APACHE II and p-POSSUM scores had a higher sensitivity and specificity in comparison to MPI for predicting the mortality in perforation peritonitis.
Distal radial access for routine consideration in coronary angiography-safety and feasibility study
Authors: Das Santanu , Haque M. D. Azizul , Ranjan Rajeev , Chatterjee Pritam Kumar
Published: April 2022

Background: Traditionally transfemoral and proximal radial access sites are chosen for percutaneous coronary intervention (PCI) but both these access sites have periprocedural complications with respect to bleeding and radial artery occlusion respectively. Distal radial arterial access has advantages over the two in terms of patient comfort and almost nil periprocedural complications including radial artery occlusion (as the access is distal to the palmar arch) and preservation of proximal radial artery for future procedures like chronic haemodialysis and bypass graft conduit. This study sought to determine the safety, feasibility and advantages of the distal radial artery as routine access site for percutaneous coronary interventions.Methods: Between March and August 2019 a total of 70 patients were taken up for distal radial intervention (33 only CAG (coronary angiography), 37 adhoc PCI) after obtaining written informed consent before procedure.Results: Of all the patients undergone CAG and PCI the success rate for puncture and access was 94% with 4 failures with crossover to proximal radial thereof. Periprocedural course remained uneventful and radial pulse palpable well in both distal and proximal course at the time of discharge. Follow-up for further 1 months also showed no access site related complications.Conclusions: Among patients undergoing PCI distal radial access is definitely a low risk, feasible procedure without any periprocedural complications. It should, therefore be recommended the first-choice access site for all PCI procedures.
Size and morphology of sella and volumetric evaluation of pituitary gland: a radiological survey
Authors: Goyal Diksha M. , Nagapurkar Abhijeet D.
Published: April 2022

Background: Sella turcica is an important anatomical structure in the middle cranial fossa. It’s size follows the size of pituitary gland. The present study aimed to evaluate the size and morphology of sella and pituitary gland in the same patients without known hormonal or pituitary pathology.Methods: In this cross-sectional observational study three hundred patients underwent lateral x-ray of skull for sella turcica measurements and MRI brain for pituitary gland measurements.Results: We observed normal shape of sella (round or oval) in 66.7% of the study participants. Maximum mean anterior-posterior (AP) dimension was seen in the age group of 41 to 50 years (1.24±0.19 cm), while maximum length (0.87±0.12 cm), depth (0.87±0.21 cm) and volume (0.49±0.21 cu cm) was observed in the age group of 51 to 60 years. Similarly, CC dimension was observed to be maximum in the age group 41 to 50 years (5.9±0.51 mm). Study participants of age group more than 60 years had the maximum mean transverse dimension (12.73±0.29 mm) and the pituitary volume on MRI was observed to be maximum for the age group 51 to 60 years (398.45±61.24 cu mm).Conclusions: In our sample of 300 patients, sella turcica was normally shaped in 66.7%. Various dimensions of sella turcica and pituitary gland increased significantly till 50 to 60 years of of age, after which they decreased.
Plasmacytoma of clavicle bone: a case report
Authors: Agrawal Anurag M. , Sharma Vidhyasagar V. , Halughodu Amruthavarshini S.
Published: April 2022

Plasmacytoma refers to a malignant tumor composed of plasma cells, which grows within soft tissue or axial skeleton. These are identical to those in plasma cell myeloma, which appears as a solitary lytic lesion on radiological examination. Primary bone tumor of clavicle are uncommon and likely to be malignant. Systemic issues in multiple myeloma are absent in plasmacytoma which makes it a formidable diagnostic challenge. Authors report a case of sixty-two years old female with progressive swelling around medial end of right clavicle associated with pain and restriction in arm movements. X-ray revealed lytic lesion in medial one-third of clavicle. FNAB revealed small to large plasmacytoid cells. CT Angiography revealed ill-defined heterogenous soft tissue density lesion. Since the mass was near the vascular structure, adjuvant chemoradiotherapy was given. Solitary plasmacytoma of bone (SPB) of medial end of clavicle is rare. Surgery is the mainstay treatment but in inoperable cases, adjuvant therapy may be considered. SPB of clavicle is a unique surgical entity with diagnostic and management challenges.
A comparative study of bilateral lsias verses conservative management in acute anal fissure
Authors: Kaur Harpreet , Ray M. S. , Malhi S.S. , Thakore Digpal , Modi Naresh
Published: April 2022

Background: Anal fissure is a tear in anal canal just below dentate line. It can be acute or chronic. In most patients, it is located in posterior midline. Its treatment is both conservative and surgical. In conservative management, there are no clear guidelines and its goal is to break the cycle of anal sphincter spasm allowing improved blood flow to fissured area for healing. Surgery is considered for patients not responding to conservative measures and its gold standard is lateral internal sphincterotomy.Methods: This prospective study was conducted among 60 patients with acute anal fissure. Patients were randomly divided into two study groups based on treatment protocols conservative management and Bilateral LSIAS. Prior informed written consent was obtained. Demographic profile, history, investigations, diagnosis, treatment and follow-up data was recorded and analyzed.Results: Patients with Bilateral LSIAS got pain relief immediately after surgery. 57% patients with conservative management reported head-ache and perianal itching. Over 86% of patients with Bilateral LSIAS got relief from pain and discomfort after treatment; around over 46% patients with conservative approach, had pain and discomfort after 6 weeks of treatment.Conclusions: Results show that Bilateral LSIAS surgery is a better approach than conservative management of anal fissure. Further, the Bilateral LSIAS surgery has maximum chances of early recovery and pain relief and reduced chances of progression to chronic anal fissure. Hence, we can conclude that for anal acute fissure, Bilateral LSIAS surgery procedure is the treatment of choice.
Port site infections after laparoscopic cholecystectomy
Authors: Kumari Chandrakala , Narain N. P.
Published: April 2022

Background: Port site infection (PSI) is an infrequent surgical site infection that complicates laparoscopic surgery but has a considerable influence in the overall outcome of laparoscopic cholecystectomy. The aim of this study was to evaluate factors that influence PSI after laparoscopic cholecystectomies and to analyze which of these factors can be modified to avoid PSI in a trail to achieve maximum laparoscopic advantages.Methods: Swabs were taken for culture and sensitivity in all patients who developed PSI. Exploration under general anesthesia, for patients, had deep surgical site infections and wound debridement been done, excisional biopsies had been taken for histopathological studies, and tissue samples for polymerase chain reaction for detection of Mycobacterium tuberculosis was done. All patients were followed up for six months postoperatively.Results: Port site infection rate was recorded in 40/889 procedures (4.5%), higher rates were observed in male patients 8/89 (8.9%), in acute cholecystitis 13/125 (10.4%), when spillage of bile, stones or pus occurred 24/80 (30%), and at epigastric port 32/40 (80%). Most of the PSI were superficial infections 77.5% with non-specific microorganism 34/40 (85%).Conclusions: There is a significant association of port site infection with spillage of bile, stones, or pus, with the port of gallbladder extraction and with acute cholecystitis. Especial consideration should be taken in chronic deep surgical site infection as Mycobacterium tuberculosis could be the cause. Most of the PSIs are superficial and more common in males.