bluuebunny/crossref_metadata_2025 huggingface dataset:
Credit Supply, Prices, and Non-price Mechanisms in the Mortgage Market
Authors:   Federal Reserve Bank of San Francisco, Mondragon John
Published: August 2024

I use an episode of relatively tight credit supply in the jumbo mortgage market to quantify the importance of price and non-price credit supply mechanisms in explaining changes in borrowing. Following market disruptions in March 2020, borrowers with jumbo loans saw significantly tighter credit supply conditions relative to borrowers with conforming loans. As a result, jumbo borrowers were 50 percent less likely to refinance and when they refinanced they borrowed 4-6 percent less than counterfactual borrowers facing looser credit conditions. The reduction in borrowing may have been caused by both an increase in the price and a change in a non-price mechanism, a decline in the availability of cash-out refinances. Decomposing the total effect into a price and cash-out channel, I find that that the cash-out channel accounts for two to three times as much of the decline as the price effect, and together both explain 70-80 percent of the total decline. This suggests that non-price mechanisms can be least as important as prices in clearing credit markets, a fact which is not adequately explained by current models of credit markets.
Leveraging quick response (QR) Codes for horticultural information access: A stakeholder perspective
Authors: Atheequlla G A , Vasanthi C , Mahadevaiah C , Dhananjaya M V , Ramya H R
Published: August 2024

In the context of horticulture’s crucial role in economic growth, nutritional security and employment, the sector faces challenges related to dissemination of credible scientific information, particularly in rural areas. The gap in information access leads farmers to rely on experiential knowledge and peer opinions. Leveraging information and communication technology (ICT), specifically quick response (QR) codes, presents an innovative solution to bridge this information gap. This paper investigates stakeholders’ awareness, utilization, size and display distance and constraints in utilizing QR codes for accessing horticultural information. The findings indicated that 93.33% of the respondents reported previous usage, highlighting the technology’s ubiquity and acceptance. Moreover, stakeholders expressed positive inclination towards QR code adoption for accessing horticultural information, with 53.33% expressing likelihood to embrace QR technology. Effect of QR code size on the display board and their display distance on the usability and adoption was also studied, which indicated, 71.22% accessed QR codes on large displays of size 8" x 11", while, 16.66% accessed them on small displays of size 4" x 5". However, despite the positive reception, several challenges impede QR code utilization. Poor internet network connectivity (mean score: 71.00) during National Horticultural Fair (NHF-2024) emerges as a significant barrier, alongside entrenched preferences for traditional methods (mean score: 69.00). By aligning QR code designs with stakeholders’ preferences and addressing constraints, horticultural stakeholders can leverage QR codes more effectively, fostering knowledge dissemination and driving horticultural development.
I Workshop AI in Architecture
Authors:   Expo I Workshop AI in Architecture (1ª : 2024 : UAM Azcapotzalco)., Morales García Tannya Berenice , Arroyo Jiménez Ricardo , Colin Sandoval Lorena , Fernández de Anda Claudia Gabriela , Rusinov George , Haddad Paul , Lulea Ana María , Prodan Savina María , Eftene Teodora Alexandra , Guerrero Gutiérrez Luis Fernando , Echanove Cuevas Pablo Arturo , Rincon Jon Pau , Boujana Marcucci Sakina , Zacarias Fernández Aaron , Moratalla González Lucía , Morales Gutiérrez Aarón , Márquez Hernández Yael , Martínez Espinoza Jesús Vicente , Herrera Polanco Diego , Zollo Fabio , Proietti Marco , Lixandru Andrei Cristian , Militaru Ameli Mihaela , Popa Ioana-Stefania , Pérez López Sofia , Navarro Parra Héctor Alejandro , Madrid Rea Alejandro , Salcido Moran Edgar Everardo , Cocosila Bianca-Maria , Draganescu Maria-Cerasela , Lacatusu Stefana-Georgiana , Mischie Damiana-Andreea , Villa Barrios Alejandra , Uribe Cordova Carlo , Silva Montaño Christian Everardo , Alradi Raluca Andreea , Boncoi Ada Cristina , Grosari Marta Ioana , Voinescu Georgiana Andreea , Lessage Herrera Andrea María , Jiménez Peña María Regina , Romo Maldonado José Eduardo , García Sánchez Rodolfo , Jaramillo Villalobos Jesús Mauricio , Zárate Benítez Carlos Francisco , Salinas Ayala Vannia Alejandra , López Garza Valeria , Marines Niño Diego Alejandro , Mireles Lira Adríán , Quijano Wolberg José Eugenio , Hernández Nájera, Sebastián Emiliano
Published: August 2024

Las infografías que se presentan, tienen como objetivo dar a conocer los resultados del Primer Taller Internacional de Inteligencia Artificial en Arquitectura, que se llevó a cabo del 29 de febrero al 6 de marzo de 2024. Este evento es el producto de más de cinco años de colaboración entre académicos de diversas instituciones, quienes anualmente desde 2020 han realizado talleres internacionales de Arquitectura. En esta ocasión, el enfoque fue explorar el impacto de la Inteligencia Artificial en el diseño y la práctica arquitectónica. Participaron 80 esudiantes de 5 escuelas de Arquitectura, provenientes de diferentes países. Junto a ellos, 30 asesores expertos guiaron los procesos de investigación y desarrollo durante 54 horas de intenso trabajo a lo largo de 5 meses de organización. Esta exposición busca compartir con ustedes los procesos y éxitos de este ejercicio colaborativo, en donde nuestros jóvenes arquitectos de los últimos trimestres y posgrados, exploraron las oportunidades que la Inteligencia Artificial ofrece para la concepción, visualización y optimización de proyectos arquitectónicos.
Value for money financial governance, level of investment, and quality of regional development in Indonesia
Authors: Putra Rediyanto , Pujiono Pujiono , Kusumaningtias Rohmawati , Ardhiarisca Oryza , Wijayanti Rahma Rina
Published: August 2024

Introduction/Main objectives: This study aims to test the influence of the application of the concept of value for money on regional government financial management at the quality level of regional development, which is determined by the level of foreign and domestic investment in local governments. Background problems: State the problem or economic/business phenomena studied in this paper and specify the research question(s) in one sentence. Novelty: This study has a research model that has yet to be widely carried out in Indonesia, namely, a moderated model regression analysis of the value concept for money on the quality of regional development with investment as a moderating variable. Research methods: This study uses data on financial performance, domestic and foreign investment levels, and human development index of 34 provincial governments from 2017 to 2021. This research data comes from the website of the Directorate General of Fiscal Balance, Ministry of Finance and the Central Bureau of Statistics. The data collected in this study is then analyzed using moderated regression analysis (MRA) with the SPSS ver 23.0 application. Findings/Results: The findings in the research show that the application of value for money ( economics, efficiency, and effectiveness ) from local government financial governance can influence the quality of regional development in Indonesia’s provinces in 2017–2021. In addition, the existence of foreign and domestic investment in the provincial government also strengthens the influence of value-for-money financial governance on the quality level of regional development in the provincial government. Conclusion: Based on existing research, local government financial management applies the concept that value for money needs to be increased to create optimal public services to improve the quality of human development in the regions. Regional governments are also expected to be able to encourage the level of capital investment both domestically and abroad to support the creation of development that can strengthen the quality of regional development in the regions.
The role of government and community participation in realizing sustainable tourism development in Tihingan Village, Bali, Indonesia
Authors: Nugraha I Gede Putra , Parma I Putu Gede , Agustina Made Dian Putri , Hutnaleontina Putu Nuniek
Published: August 2024

Emphasis has been placed on the swift implementation of sustainable tourism development, particularly in rural areas. This is because of the government’s and local communities’ suboptimal involvement in sustainable tourism development. This study aimed to examine the role played by government and community participation in the development of sustainable tourism in Tihingan village, Bali. The quantitative research was designed by conducting observations, in-depth and structured interviews, and distributing questionnaires to people directly involved in tourism activities and with economic links in Tihingan Village, such as tourism village managers, homestays, restaurants, traders, and other tourism organizations. A total of 57 participants were included, and the sample was analyzed using purposive sampling. All the data were analyzed using multiple linear regression with a probability of p < 0.05. The results indicate that government involvement (p = 0.007) and community participation (p ≤ 0.001) play significant roles in shaping sustainable tourism development (R2 = 0.525). This finding implies that 52.5% of the variation in sustainable tourism can be attributed to these factors, while the other variables account for the remaining influence. Strategic policies related to natural resource development, environmental protection, and local community empowerment can create conditions that support the growth of environmentally friendly tourism and provide continued economic and social benefits in villages. Community participation is realized by supporting policies launched by local governments to accelerate sustainable tourism development. The outcomes of this research will aid the government in devising policies concerning sustainable tourism development through the active participation of the local community.
The State Intelligence Agency (BIN) amid the 2024 general election in Indonesia
Authors: Surjatmodjo Dwi , Unde Andi Alimuddin , Cangara Hafied , Hasanuddin Zulfajri
Published: August 2024

This research explains the relationship between the State Intelligence Agency (BIN) and politics in Indonesia. The involvement of the State Intelligence Agency (BIN) in the 2024 general election in Indonesia is the main focus of this research. This research describes the long history of the establishment of the State Intelligence Agency (BIN) in Indonesia and its relationship with political contestation throughout Indonesian history. In the 2024 general election, President Joko Widodo conveyed to the public the existence of Intelligence information related to political parties participating in the election. This then shocked the public because it indicated the use of state institutions in practical political activities. This research uses a qualitative methodology with a literature review that relies entirely on secondary data sources in the form of written texts. And using data triangulation techniques as part of the data processing analysis. The research explains that Indonesia’s 2024 elections face three central issues that continue from 2019: identity politics, the impact of socio-political divisions, and political buzzers. These issues are considered threats that could disrupt a conducive situation. The role of the National Intelligence Agency (BIN) is of particular concern, but allegations of BIN’s non-neutrality have led to public distrust. History shows that Indonesian Intelligence and politics have always been closely linked.
Veterinary students' perceptions toward incorporating and expanding telehealth service delivery knowledge in curricula and future practice: a cross-sectional study
Authors: Watson Kylie , Mardhekar Nikhil M. , Pandey Utkarsh , Wells Julia , Gruszynski Karen , Wilkerson Amanda H. , Dascanio John J. , Quadri Syed S. , Leo Jonathan T. , Samuel Krishen D. , Nahar Vinayak K. , Davis Robert E.
Published: August 2024

OBJECTIVE

Telehealth is the use of technology to deliver medical services. Potential uses among veterinarians include consulting with specialists about complicated cases, sending in electronic prescriptions, or meeting with clients to discuss patient health. Although the coronavirus disease 2019 pandemic posed many challenges to the veterinary profession, it accelerated the adoption of telehealth among veterinarians. As many of these changes took place quickly in response to the pandemic, many of those in practice did not receive much training or guidance; therefore, this study explores veterinary students’ perceptions regarding incorporating telehealth into the veterinary curriculum and the utilization of telehealth in the future.

METHODS

An email survey was sent to students at a veterinary school.

RESULTS

80 students provided answers to the 11-question survey. Nearly 80% reported that it is either “important” or “very important” to incorporate telehealth training into the veterinarian curriculum, whereas almost 90% indicated that they would benefit from more telemedicine training prior to graduation. Almost 75% of participants had legal and malpractice concerns, which may present a barrier to using the technology upon graduation.

CONCLUSIONS

This study suggests that veterinary schools should explore how to incorporate telehealth training into their curriculum, especially in regard to navigating the potential pitfalls that may be encountered when employing telehealth within the context of a veterinarian-client-patient relationship.

CLINICAL RELEVANCE

Telehealth is a valuable tool, and its use has become commonplace. Educational programs that emphasize telehealth will better equip future clinicians to manage the nuances of this modality in practice.
Community awareness for GERD extra gastrointestinal manifestations
Authors: Senaidy Yasir , Alodami Basil , AlQarni Ayedh , Alatiwi Abdulmajeed , Al-Barrak Abdullah , Alabduljabbar Faisal , Altreef Wail
Published: August 2024

Objective: This study aimed to explore the population's knowledge of extraintestinal manifestations (EIMs) of gastroesophageal reflux disease (GERD).
Methods: A cross-sectional study was implemented through an online survey aimed at adults from five different regions across the country, containing demographical data and questions relating to GERD EIMs, and questions relating to the knowledge of extra systemic symptoms in general.
Results: A total of 1,045 submissions were included. Demographical data showed predominantly male and local participants. Most participants (54%) claimed to have a "medium" level of knowledge regarding GERD EIMs. As for the medical and family history of GERD, 20.1% and 28.9% of participants had positive medical history and family history, respectively. Significant differences were also detected among different participants' genders, educational levels, and age groups.
Conclusions: Significant deficits were found amongst several demographic variables indicating non-satisfactory results. Most of the population acknowledged limitations to their awareness shown by their submissions.
Interferences in Addictive Drugs and Ethanol Analysis
Authors:   Ankara Bilkent City Hospital, Gök Gamze
Published: August 2024

Addiction can be defined as an irresistible desire for an individual, an object, or a being, even though it harms the person psychologically or physically. In addiction, after starting to use the substance, negative effects such as the development of tolerance and withdrawal to the substance and changes in emotional states occur.
Caring in Crisis: The Impact of Systemic Failures and Patient Loss on Behavioral Health Clinicians
Authors:   Assumption University, Williams Christian
Published: August 2024

Background: The opioid epidemic continues to be one of the most formidable public health challenges, with overdose deaths significantly impacting individuals, families, and communities. This qualitative study explores the experiences of clinicians who have lost patients to opioid overdose, shedding light on the systemic challenges they face within the field of Substance Use Disorder (SUD) treatment.
Wavelet-Based Characterization of Spatiospectrotemporal Structures in F404 Engine Jet Noise
Authors: Olaveson Tyce W. , Gee Kent L.
Published: August 2024

Spatiospectral lobes are significant contributors to noise radiated from full-scale tactical aircraft. Prior studies have explored lobe frequency-domain characteristics, but a joint time–frequency domain analysis has the potential to further describe these phenomena and connect them to source-related events in the time waveform. This paper uses acoustical data collected from a 120-microphone array near a T-7A-installed F404 engine to characterize the spatiospectral lobes in combinations of the time, frequency, and spatial domains. An event-based beamforming method is used in conjunction with a wavelet transform to determine propagation angles and event source locations corresponding to each of the lobes. Temporospectral events in the wavelet transform are then analyzed using Markov chains. Finally, spatiospectral maps created from the measured data are decomposed into individual lobes using events in the wavelet transform as a guide. The spatiospectrotemporal combination of these three analyses shows that the lobes originate from multiple, overlapping regions along the jet lipline and that each lobe has its own peak radiation angle. Additionally, events corresponding to the spatiospectral lobes occur intermittently and at different times from each other, leading to bursts of acoustic energy with rapidly changing directivities.
Application of Time-Variant Systems Theory to the Unsteady Aerodynamics of Rotary Wings
Authors: Quero David
Published: August 2024

This work employs the principles of time-variant systems theory to investigate the unsteady aerodynamics of rotary-wing configurations under periodic equilibrium conditions. Their application enables an extension of the pulse technique for system identification, as well as the adaptation of the linear-frequency-domain formulation commonly utilized in fixed-wing to rotary-wing scenarios. These methodologies effectively incorporate the aerodynamic nonlinearities associated with the equilibrium state into an efficient time-variant linearized representation of the unsteady aerodynamics. To promote its application in the context of rotary-wing aeroelasticity, a state-space realization based on a periodic autoregressive model with exogenous input is subsequently employed. Upon transformation from discrete to continuous time, the resulting aerodynamic model adopts a linear continuous-time periodic state-space formulation, offering compatibility for its coupling with a wide range of structural models. The proposed aerodynamic framework tailored to rotary-wing aeroelasticity holds applicability across a spectrum of aerodynamic models of arbitrary complexity, spanning from incompressible potential flow approximations to potentially more sophisticated methods. Showcasing the potential of this framework, the widely studied lossy Mathieu equation and the aerodynamic response to a flap perturbation about the periodic equilibrium condition of a prototypical rotor blade section, incorporating nonlinearities through an analytical dynamic stall model, are considered.
Reconstruction of Mars 2020 Backshell Radiative Heating via Infrared Emission Spectroscopy of CO2/N2/Ar Shockwaves
Authors: Tibere-Inglesse Augustin C. , West Thomas K. , Jelloian Christopher C. , Minesi Nicolas Q. , Spearrin R. Mitchell , Clarke Justin , di Mare Luca , McGilvray Matthew , Cruden Brett A.
Published: August 2024

A test series was performed in the Electric Arc Shock Tube (EAST) facility with the aim of reproducing flight conditions encountered during the Mars 2020 mission entry into the Mars atmosphere. For this test series, the EAST facility was instrumented with two spectrometers for optical emission spectroscopy (OES) measurements and three mid-infrared lasers for tunable diode laser absorption spectroscopy (TDLAS). This paper focuses on the spectrally and spatially resolved radiance measured with OES. Conditions were chosen to achieve similarity to backshell radiative heating measured with the MEDLI2 heat flux gauges near and after the time of peak heating. Comparisons were made against two candidate kinetic models for Mars entry. Below [Formula: see text], the chemistry is effectively frozen, with measurements being above both models and CEA predictions. It is shown that taking into account shock deceleration in the tube explains most of the discrepancy between measured and frozen radiance. For velocities above [Formula: see text], the data lies between the two models. However, adjusting for shock deceleration indicates that one of the models may be preferred for predicting [Formula: see text] dissociation. Finally, comparisons between OES and TDLAS data are made and show a good agreement on the measured temperature and [Formula: see text] number density profiles, typically within 10 and 5%, respectively. A good agreement is also observed for the radiance that would be inferred based upon the quantities measured by TDLAS.
ON THE NEED TO IMPROVE APPROACHES TO ESTABLISH INGEMERGENCY PLANNING ZONES FOR NUCLEAR FACILITIES
Authors: Курындин А.В. , Сорокин Д.В. , Шаповалов А.С. , Шарафутдинов Р.Б. , Иванов Е.А.
Published: August 2024

В соответствии с российской и международной практиками для целей снижения радиационного воздействия на население при авариях, возможных на объектах использования атомной энергии, вокруг данных объектов должны быть установлены зоны и расстояния противоаварийного планирования. В соответствии с рекомендациями МАГАТЭ в пределах указанных зон и расстояний противоаварийного планирования должны быть запланированы меры по защите населения, своевременная реализация которых обеспечит снижение радиационного воздействия на население при авариях.Российская нормативная база характеризуется разнообразием подходов к противоаварийному зонированию территорий вокруг объектов использования атомной энергии, в том числе данные подходы отличаются в зависимости от типа объекта использования атомной энергии, а также его параметров, характеризующих радиационное воздействие на население при авариях.Представлен анализ нормативной базы Российской Федерации в области использования атомной энергии в части установления зон и расстояний противоаварийного планирования на предмет соответствия наилучшим международным практикам. На основании результатов выполненного анализа авторами сформулированы предложения по дальнейшему совершенствованию нормативной базы Российской Федерации в области использования атомной энергии.

In accordance with Russian and international practices, in order to reduce the radiation exposure to the population in case of potential accidents at nuclear facilities, emergency planning zones and emergency planning distances should be established around the facilities. In accordance with the IAEA recommendations arrangements to protect the population should be planned within the specified emergency planning zones and emergency planning distances and timely implementation of these arrangements will ensure a reduction in the radiological impact.The Russian regulatory framework is characterized by variety of approaches to emergency zoning of territories around nuclear facilities, including differentiation of the approaches depending on the type of nuclear facility, as well as its radiological impact due to accidents. Presented is an analysis of the legal and regulatory framework of the Russian Federation in the field of the nuclear energy use in terms of establishing emergency planning zones and emergency planning distances to follow the best international practices. Based on the results of the analysis performed, the authors proposed measures to further improvement of the legal and regulatory framework of the Russian Federation in the nuclear energy use.
Integrating of Nickel Hexacyanoferrate with Hollow Mesoporous Carbon Spheres (HMCSs) for Highly Efficient Capacitive Deionization
Authors: Zhang Shu , Li Feihu
Published: August 2024

Capacitive deionization (CDI) is a promising technology for seawater desalination, offering a green, low-cost, and low-energy alternative to traditional methods. However, its widespread adoption relies on the development of high-performance electrode materials. Prussian blue analogs (PBAs), such as NiHCF, are attractive candidates due to their high theoretical ion storage capacity but often suffer from poor conductivity and structural integrity. To address these limitations, we designed a group of hierarchical composite materials (i.e., PBA@HMCS) by integrating NiHCF with hollow mesoporous carbon spheres (HMCS) using a stepwise "ship-in-the-boat" approach. This composite combines the protective and conductive roles of carbon materials with the high ion storage capacity of PBAs. The resulting PBA@HMCS electrodes demonstrated exceptional CDI performance, with a maximum salt adsorption capacity of 80.5 mg g−1 in 500 mg L−1 NaCl solution at 1.2 V. Notably, the core-shell PBA@HMCS-1 electrode exhibited enhanced cycling stability, while the unwrapped PBA micropellets showed reduced performance. Furthermore, our investigation revealed the high affinity of PBA@HMCS electrodes for Na+ over other ions in synthetic brine, and particularly, the yolk-shell PBA@HMCS-3 electrode demonstrated high repulsion to K+, highlighting its potential for selectively extracting specific ions from dicationic brines with K+ ions. This study highlights the vast potential of hierarchical yolk-shell PBA@HMCS as a promising CDI electrode design and underscores the need for continued exploration into hierarchical structured PBA-based materials with tunable features to further enhance their CDI performance.
Exploring Ion Polarizabilities and Their Correlation with Van der Waals Radii: A Theoretical Investigation
Authors: Smith Madelyn , Khatiwada Richa , Li Pengfei
Published: August 2024

Polarizability (⍺) is a fundamental property which measures the tendency of the electron cloud of an atom, ion, or molecule to be distorted by electric field. Polarizability contributes to important physical properties such as molecular interactions or dielectric constants; thus, it is essential to have accurate polarizabilities in molecular simulations. However, it remains a challenge to develop polarizable force fields for ions in computational chemistry. In particular, a comprehensive set of polarizabilities for ions has not been derived. Herein, we derived a systematic set of polarizabilities for atoms and ions across the periodic table based on high-level quantum mechanics calculations. These values have excellent agreement with experimental data. Furthermore, we examined the relationship between the obtained polarizabilities and the van der Waals radii (R_VDW) that we previously determined (J. Chem. Theory Comput., 2023, 19, 2064). Two relationships, R_VDW∝α^(1/7) and R_VDW∝α^(1/3), proposed in previous studies were examined in the present work. Our results indicated the former relationship, which was derived based on the quantum harmonic oscillator model, prevails for atoms and cations, but neither relationship provides a satisfactory fit for anions. This is consistent with the tight-binding nature of the electrons in atoms and cations, while it is more challenging to quantify the polarizabilities of anions because of their more dispersed electron clouds. Moreover, we compared different approaches to determine the dispersion coefficients, including the London equation, Slater-Kirkwood equation, SAPT calculations, and TD-DFT method, along with the approach based on van der Waals constants. Our results indicated that although different approaches predict deviated magnitudes for the dispersion coefficients, their predictions are highly correlated, implying that each of these approaches can be used to evaluate dispersion interactions after proper scaling. Finally, we have developed a parameterization strategy for the 12-6-4 model based on our study. We specifically compared the performance of the 12-6-4 model with SAPT and SobEDA analyses to model interactions involving Na+/Mg2+ and various ligands containing He, Ne, Ar, H2O, NH3, [H2PO4]−, and [HPO4]2−. The results demonstrate that the 12-6-4 parameters effectively replicate both the total interaction energy and the individual energy components (electrostatics, exchange-repulsion, dispersion, and induction), highlighting the physical relevance of the 12-6-4 model and the effectiveness of our parameterization approach. This study has significant implications for advancing the development of next-generation ion models and polarizable force fields.
Current Status of the MB-pol Data-Driven Many-Body Potential for Predictive Simulations of Water Across Different Phases
Authors: Palos Etienne , Bull-Vulpe Ethan F. , Zhu Xuanyu , Agnew Henry , Gupta Shreya , Paesani Francesco
Published: August 2024

Developing a molecular-level understanding of the properties of water is central to numerous scientific and technological applications. However, accurately modeling water through computer simulations has been a significant challenge due to the complex nature of the hydrogen- bonding network that water molecules form under different thermodynamic conditions. This complexity has led to over five decades of research and many modeling attempts. The introduction of the MB-pol data-driven many-body potential energy function marked a significant advancement toward a universal molecular model capable of predicting the structural, thermo- dynamic, dynamical, and spectroscopic properties of water across all phases. By integrating physics-based and data-driven (i.e., machine-learned) components, which correctly capture the delicate balance among different many-body interactions, MB-pol achieves chemical and spectroscopic accuracy, enabling realistic molecular simulations of water, from gas-phase clusters to liquid water and ice. In this review, we present a comprehensive overview of the data- driven many-body formalism adopted by MB-pol, highlight the main results and predictions made from computer simulations with MB-pol to date, and discuss the prospects for future extensions to data-driven many-body potentials of generic and reactive molecular systems.
Hyaluronic Acid-based Inks for Stereolithography (Bio)printing: Benefits of Thiol-ene vs. Acrylate Functionalized Inks
Authors: Steudter Therese , Lam Tobias , Pirmahboub Hamidreza , Stoppel Christian , Kloke Lutz , Pearson Samuel , del Campo Aránzazu
Published: August 2024

Hydrogel inks used for 3D bioprinting are mainly based on radical polymerization of methacrylate groups. Inks based on the radical thiol-ene polymerization have raised attention in recent years, as they are not susceptible to oxygen inhibition and require lower light doses for polymerization, therefore, they can be more benign to living cells. Here, we modified hyaluronic acid inks with allyl ether or norbornene groups, which can form a crosslinked network in the presence of a dithiol crosslinker. We performed systematic studies to compare precursor stability, photocrosslinking and printability of the thiol-ene inks with methacrylated hyaluronic acid inks. Our results showed higher storage stability of the thiol-ene hydrogel precursors over 15 months. Photorheology experiments demonstrated faster photocrosslinking and higher temporal control over the network formation in thiol-ene inks. The suitability of thiol-ene inks was demonstrated using digital light processing-based printing with a minimum print time of 2 s per layer and a xy resolution of 100 µm.
Bottom-up Precision Engineering of Porous Medium for High-Performance Chromatography Based on Stereolithography 3D Printing
Authors: Wen Hanrong , Lu Haonan , Zhou Zhuoheng , Huang Yinjia , Zeng Juxing , Sun Kaiyue , Wang Yuchen , Luo Lianzhong , Xu Chen , Xu Jianzhong , Zhang Xin , Wang Xiaofei , Eeltink Sebastiaan , Zhang Bo
Published: August 2024

Engineering of high-performance chromatography medium, has long been esteemed as an art rather than science, this raised a great challenge in securing separation consistency, method transferability and scaling-up in purification of biomolecules. Herein, we report a bottom-up engineering strategy for chromatography media utilizing 3D-printing technology. Combining micrometer stereolithography and nanometer pore chemistry, the strategy enables precision engineering of high-performance separation media in diverse scales, shapes and chemistry. Between 1,000 devices, exceptional performance consistency was demonstrated by superb column-to-column and batch-to-batch reproducibility (retention time CV 2.04%). Ultra-fast separations of intact proteins and antibodies were realized in reversed-phase and hydrophobic interaction chromatography: within 1 minute, resolution > 1.5 was achieved. Purification of native proteins was directly amplified three orders of magnitude: 12 mg hemeproteins were isolated in 8 min at negligible scaling-up cost, supporting liter-scale processing within 7 h on one 20 mm i.d. column. With unprecedented advantages in fully automatic and parallel production capacity, high-fidelity microstructure and chemistry across dimensions, and highly efficient method transfer and scaling-up, the stereolithography engineered chromatography media may open a green and sustainable path to speeding up separation and purification processes from primary analysis to mass-production of biomolecular entities, as demanded in biosynthesis and pharmaceutical industries.
Integrating Compositional and Structural Diversity in Heterometallic Titanium Frameworks by Metal Exchange Methods
Authors: Martí-Gastaldo Carlos , Gómez-Oliveira Eloy P. , Castells-Gil Javier , Chinchilla-Garzón Clara , Uscategui-Linares Andrés , Albero Josep , Almora-Barrios Neyvis , Tatay Sergio , M. Padial Natalia
Published: August 2024

The increasing use of Metal-Organic Frameworks (MOFs) in separation, catalysis or storage is linked to the targeted modifi-cation of their composition or porosity metrics. While modification of pore shape and size necessarily implies the assembly of alternative nets, compositional changes often rely on post-synthetic modification adapted to the functionalisation or exchange of the organic linker, or the modification of the inorganic cluster by metal exchange methods. We describe an alternative methodology that enables the integration of both types of modification, structural and compositional, in titanium MOFs by metal exchange reaction of the heterometallic cluster Ti2Ca2. A systematic analysis of this reactivity with MUV-10 is used to understand which experimental variables are crucial to enable replacement of calcium only, or to integrate metal exchange with structural transformation. The isoreticular expanded framework MUV-30, is next used to template the formation of MUV-301, a titanium framework not accessible by direct synthesis that displays the largest mesoporous cages reported to date. Given that the interest of Ti MOFs in photoredox applications often meets the limitations imposed by the challenges of titanium solution chemistry to design concrete candidates, this soft strategy based on pre-assembled frameworks will help integrating specific combinations of metals into highly porous architectures.
Electronically transparent Ag-C(sp3) contacts result in low conductance junctions
Authors: Czyszczon-Burton Thomas , Montes Enrique , Prana Jazmine , Lazar Sawyer , Rotthowe Nils , Chen Sully , Vazquez Hector , Inkpen Michael
Published: August 2024

Chemical groups capable of connecting molecules physically and electrically between electrodes are of critical importance in molecular-scale electronics, influencing junction conductance, variability, and function. While the development of such linkage chemistries has focused on interactions at gold, the distinct reactivity and electronic structure of other electrode metals provides underexplored opportunities to characterize and exploit new binding motifs. In this work we show that 𝛼,ω-alkanedibromides spontaneously form well-defined junctions using silver, but not gold, electrodes. Through application of the glovebox-based scanning tunneling microscope-based break junction method, we find that the same junctions form when using different halide, or trimethyltin, terminal groups, suggestive of an electronically transparent silver-carbon(sp3) contact chemistry. However, the conductance of these junctions is ~30× lower than for analogous junctions formed on gold and does not align with predictions based on first-principles calculations. Through insights provided from prior temperature-programmed desorption studies and a robust series of atomistic simulations and control experiments, we propose that in these experiments we measure alkoxide-terminated junctions formed through the reaction of unstable silver-alkyl species with adsorbed surface oxygen. This study, in demonstrating that high conductance contact chemistries established using model gold electrodes may not be readily transferred to other metals, underscores the need to directly characterize the interfacial electronic properties and reactivity of electrode metals of wider technological relevance.
انعكاسات الإطار المفاهيمي للإبلاغ المالي الصادر عن مجلس معايير المحاسبة الدولية (IASB) في بيئة الممارسة المحاسبية – دراسة نظرية انتقادية
Authors: سعيد نوزاد , مصطو نارين
Published: August 2024

يستهدف البحث الحالي إلى دراسة التغيرات الرئيسية في الإطار المفاهيمي للإبلاغ المالي الصادر عن مجلس معايير المحاسبة الدولية لعام (2018) ومردودها الإيجابي والسلبي على بيئة الممارسة المحاسبية، وذلك في في إطار فلسفي يشمل استعراض وتحليل الدراسات السابقة ذات الصلة بهذه العلاقة، اذ أستخدمت البحث المنهج الوصفي الانتقادي من خلال الإطلاع على المراجع والأبحاث والدراسات التي تخص البحث، وتحليل ما تحتويه من وجهات النظر المختلفة بخصوص التغييرات الجوهرية في الإطار المفاهيمي الجديد. وخلص الباحثان من تحليل تلك الدراسات، بأن الإطار المفاهيمي الجديد وما تتضمنه من تحديثات ساهمت بشكل جوهري في توجيه الممارسات المحاسبية بشكل الصحيح واختيار معالجات محاسبية موحدة في البيئات المختلفة، فضلاً عن إيجاد بدائل قياس ملائمة مع التغيرات والتقلبات التي تواجه تطبيقات الاعمال، الأمر الذي ترتب عليه تحسين وتعزيز محتوى جودة التقارير المالية. كما توصل الباحثان من خلال تحليل تلك الدراسات بأن الإطار المفاهيمي الجديد لم تغطي للكثير من المجالات الجديدة في بيئة الممارسة المحاسبية، فضلاً عن عدم وضوح الإرشادات في بعض المجالات الموجوده به خاصة تلك المجالات التي تتعلق بمبادىء القياس والعرض الاعتراف والسياسات المحاسبية. وذلك يمثل تحدياً لإصدار معايير تتصف بالكفاءة والفاعلية. في حين يوصي الباحثان ضورة تقييم التغييرات المقترحة في الإطار المفاهيمي للإبلاغ المالي من قبل الجهات المهنية ومعدي التقارير المالية ليواكب مع التغييرات التي تحدث في بيئة الممارسة المحاسبية.
A localização geográfica como fator determinante na compra de laticínios durante a pandemia COVID-19
Authors: Siqueira Kennya Beatriz , Chaves Davi Oliveira , Diniz Fabio Homero , Pacheco Flaviana Coelho
Published: August 2024

Os padrões alimentares podem variar nas regiões geográficas brasileiras, que foram afetadas de forma diferente pela pandemia de COVID-19. Este estudo teve como objetivo verificar se o local de residência dos indivíduos afetou o consumo de laticínios durante a pandemia, considerando tanto a quantidade de produto consumida quanto os fatores que influenciam na decisão de compra. Resíduos de Pearson ajustados foram utilizados para avaliar a associação entre o estado da variável e aqueles relacionados ao consumo de laticínios. A coleta de dados foi realizada por meio de um questionário online, no período de 23 de abril a 3 de maio de 2020. Os resultados mostraram que, para a maioria dos laticínios, foi observada associação significativa entre o local de residência e o consumo de laticínios. Observou-se maior associação com a manutenção ou maior consumo para as regiões com maior consumo de laticínios, sendo a marca que o consumidor costumava comprar foi o fator determinante na hora da compra, mesmo diante de uma crise financeira. Também foi possível identificar os estados que estiveram mais atentos à atuação das empresas durante a pandemia e a importância da boa alimentação em uma crise de saúde pública.
Produção de territórios informais e a regularização fundiária urbana no Maranhão, Brasil
Authors: MASULLO YATA
Published: August 2024

A dinâmica urbana brasileira, produz desafios ao desenvolvimento de políticas sociais, tendo em vista a necessidade de garantir a qualidade na prestação de serviços públicos e reduzir as distâncias sociais e econômicas da população, entre estes desafios destaca-se o direito à propriedade. O presente artigo, surge com a finalidade de analisar a dinâmica urbana e a produção dos territórios informais no Brasil e sua influência sobre o Programa Regularização Fundiária Urbana do Maranhão. De forma específica, o estudo avalia o programa estadual considerando os procedimentos metodológicos, avanços e desafios que impactam nos resultados dessa política pública. No período de 2015 e 2021, o Programa Regularização Fundiária Urbana do Maranhão reuniu um conjunto de técnicas multidisciplinares, para entregar 13 mil títulos de propriedade e beneficiar aproximadamente 50 mil pessoas. Mesmo com atuação concentrada, o programa estadual se apresentou como uma importante forma de efetivar a função social da propriedade.
A questão do Estado na Geografia Política contemporânea brasileira
Authors: Cigolini Adilar
Published: August 2024

Texto em resposta ao ensaio publicado no volume anterior.
Análise espacial dos crimes violentos letais intencionais no território de São Luís do Maranhão entre 2015 e 2018
Authors: Da Silva Fernandes Leandro , Kátia Borgneth Petrus Júlia
Published: August 2024

Este trabalho tem por objetivo apresentar, em um viés crítico, a espacialização da violência no território da cidade de São Luís, capital do Maranhão. Como forma de delimitação conceitual e metodológica, foram elencados os Crimes Violentos Letais Intencionais (CVLI), quais sejam: homicídio doloso; lesão corporal seguida de morte; e latrocínio. A obtenção dos dados foi realizada junto à Secretaria de Estado de Segurança Pública do Maranhão (SSP/MA). As informações dos crimes serão demonstradas em gráfico e em mapas temáticos anuais referentes ao período entre 2015 e 2018. Os resultados indicam, por meio do mapeamento, onde estão concentrados os casos de crimes violentos. Com base na análise dialética para a contextualização socioespacial destas áreas se revelou o processo de produção desigual do espaço da capital ao se identificarem aspectos como renda, alfabetização e declaração de cor de pele, além da principal motivação de crimes as organizações criminosas.
Territórios de (re)existência: potencialidades entre a escola pública e a cultura de periferia
Authors: Cunha Franca Gilberto
Published: August 2024

Este artigo discute as formas de resistência à gestão precarizada da escola pública a partir das próprias condições de existência das comunidades ao seu redor. Ele procura entender, mais especificamente, como o espaço escolar, através de práticas pedagógicas, pode se abrir às formas atuais de resistência dos sujeitos sociais das periferias urbanas. Trata-se de uma reflexão teórica sobre a escola a partir de uma perspectiva geográfica, e apoiada principalmente no conceito de território, como expressão da existência e da resistência coletivas. A metodologia da pesquisa é qualitativa e se apoia basicamente em revisão bibliográfica. Como resultado, a criação de espaços comuns e de comunidade de aprendizagem é apresentada como instrumento político-pedagógico de encontro de sujeitos sociais, linguagens e realidades diferentes. O artigo conclui com uma proposta de agenda de pesquisa empírica sobre a cultura da periferia nas escolas públicas.
Representação gráfica da vegetação da bacia do riacho São José na porção semiárida do Agreste pernambucano
Authors: Severo Chaves Ana Maria , Gomes Teixeira Vieira Alexandre , Melo & SOUZA Rosemeri
Published: August 2024

O ambiente semiárido que integra a faixa de transição do Agreste do Estado de Pernambuco revela mudanças na fitofisionomia do sentido de Leste para Oeste, compreendendo do Planalto Central da Borborema a Depressão do Baixo São Francisco. Essa constatação é colocada em evidência no percurso de bacias hidrográficas com forma alongada sobre as citadas feições geomorfológicas, como é o exemplo do riacho estudado. Diante desta realidade, teve-se como objetivo representar a composição florística da bacia Riacho São José-PE através de pirâmides de vegetação, destacando as interações geoecológicas das paisagens semiáridas moderada e subúmida, destacando as mudanças fitofisionômicas que se sucedem. Nessa intenção, os procedimentos aplicados são enviesados na perspectiva de uma análise integrada dos componentes geoecológicos da paisagem e a metodologia de pirâmides de vegetação disponível na literatura: levantamento bibliográfico do tema e seus métodos, construção de banco de dados cartográficos com as informações geoecológicas, atividade de campo e confecção cartográfica e gráfica. Tais ações possibilitaram a construção de quatro pirâmides a partir de áreas amostrais, levantamento de informações biogeográficas, fitossociológicas e a classificação da dinâmica vegetal por estrato. Assim foram identificadas 25 famílias e 56 espécies de vegetação arbórea, arborescente, arbustiva, subarbustiva e herbácea; nas representações gráficas diagnosticou-se os cinco estratos vegetais, com exceção da segunda pirâmide; a principal dinâmica constatada foi o estado de equilíbrio e em menor representação o estado em regressão nos estratos arbóreo da primeira e subarbustivo da terceira pirâmide. Os resultados revelaram assim a estrutura e dinâmica da vegetação uma área de transição fitogeográfica o que pode indicar prioridades para conservação da Caatinga diante do estado de regressão na dinâmica de alguns estratos e pouca representatividade de espécies nativas, bem como deve-se desenvolver novos estudos em outras áreas de Caatinga com fins a análises comparativas, pois a metodologia adotada pouco tem sido explorada nesse sentido.
Pronósticos de la tendencia diaria del Bitcoin a través de la metodología de Box-Jenkins
Authors: Chávez David Daniel Brito
Published: August 2024

Objetivo. Identificar y analizar un modelo que pronostique la tendencia diaria de la moneda electrónica Bitcoin mediante análisis de series de tiempo bajo el enfoque de Box-Jenkins.
Marco teórico: En los últimos años se han generados monedas electrónicas como el Bitcoin, como una alternativa a las formas de pago  tradicionales. Grandes tiendas online facilitan el uso del Bitcoin. Una característica del Bitcoin, su valor fluctúa de manera diaria. Esto plantea a los inversionistas la necesidad de analizar el comportamiento del Bitcoin mediante técnicas estadísticas.
Método. La metodología estadística de análisis de series de tiempo bajo el enfoque de Box-Jenkins, logra modelar las distintas componentes de una serie histórica, mediante los modelos ARIMA(p,d,q). Esta metodología pronosticar el precio de Bitcoin y sus tendencias hacía la alza o baja. Se utiliza el software estadístico abierto R.
Resultados y discusión. Se analiza una muestra de la fecha 2023-01-01 a la fecha 2023-08-02. Se estabiliza la varianza de la serie, para proceder a la modelación del precio mínimo diario. Después de especificar diversos modelos con las funciones de autocorrelación y autocorrelación parcial, se determino el modelo que mejor explica el comportamiento como el ARIMA(4,1,2), realizando las pruebas estadísticas correspondientes y el análisis de los residuales. Con este modelo se calcularon diez pronósticos con sus respectivos intervalos de predicción. Contrastando con los valores observados correspondientes, los diez están dentro de los intervalos de predicción y siete pronostican bien la tendencia de la serie.