bluuebunny/crossref_metadata_2025 huggingface dataset:
La escuela del siglo XXI: Retos digitales necesarios para dar respuesta a la realidad social y educativa
Authors: Lores Gómez Beatriz , Sánchez Thevenet Paula , García Bellido María Rosario
Published: January 2019

Esta investigación pretende identificar cuáles son los retos tecnológicos y digitales que se deben acometer en el ámbito educativo para dar respuesta a la realidad social y educativa del siglo XXI. Para ello, se ha empleado una metodología cualitativa de corte etnográfico en la cual se han realizado entrevistas en profundidad a 6 expertos del ámbito de la educación, la comunicación y las TIC. Los temas abordados han sido: la influencia de las tecnologías en la sociedad actual, las características que debe poseer el ciudadano, las necesidades formativas de los docentes, las tendencias en el uso educativo de las TIC y, las políticas educativas relacionadas con las TIC. Entre los principales resultados destaca que la introducción de las tecnologías influye drásticamente en la ciudadanía sobre la percepción del mundo, los hábitos y las costumbres y, la forma en la que nos comunicamos e informamos. Sin embargo, ante esta coyuntura, las políticas y la formación que poseen los docentes necesitan actualizarse y adaptarse a estas demandas sociales.
Educació, país, llengua
Authors: Ferré Trill Xavier
Published: January 2019

Jordi Monés i Pujol-Busquets: Educació, país, llengua, Nautilus Comunicació i Cultura, Banyoles, 2018, 479 pp.
Classification of tight oil reservoir storage space v1
Authors: Chen Fangwen , Zhao Hongqin , Lu Shuangfang , Ju Yiwen , Ding Xue
Published: January 2019

A new method for classifying tight oil reservoir storage space was introduced. The pore-throat size ranges are clssified according to pore-throat fractal characteristics, and then the tight oil reservoir storage space is classified according to the relationships between the reservoir quality and the pore volume percentage connected by pore throats with different fractal characteristics.
Weekly Quality Control v3
Authors: Snoek Lukas , Beemsterboer Tinka
Published: January 2019

The weekly quality control at the Spinoza Centre REC evaluates the signal quality/performance of the 3T Philips Achieva TX (R5, v3.0).
Immunofluorescence Assay to detect respiratory syncytial virus v1
Authors: Lucia Silva Maria , B Gagliardi Talita , Arruda Eurico
Published: January 2019

IF Protocol used to detect RSV in nasopharyngeal samples.
Adapted protocol to extract total RNA using TRIzol® (Invitrogen, Thermo) v1
Authors: B Gagliardi Talita
Published: January 2019

Total RNA extraction using TRizol reagent. Attention: for nasopharyngeal aspirates, we use regular TRizol reagent in this assay, but for blood samples it is better to use a special one as "TRizol LS".
Organisation der IT-Sicherheit in der Produktion
Authors: Niemann Karl-Heinz
Published: January 2019

Der folgende Beitrag befasst sich mit der IT-Sicherheit von Produktionsanlagen aus Betreibersicht. Hierbei liegt der Fokus auf den organisatorischen Aspekten der IT-Sicherheit. In einer Bestandsaufnahme werden zunächst die Probleme herausgearbeitet, die entstehen, sofern sich eine Organisation im Wesentlichen auf technische Aspekte der IT-Sicherheit konzentriert. Daraus wird die Notwendigkeit organisatorischer Maßnahmen abgeleitet. Eine Betrachtung von Normen und Standards, welche sich mit den organisatorischen Aspekten der IT-Sicherheit in der Produktion befassen, liefert das Grundgerüst für die Ableitung eines Maßnahmenplan. Der daraus resultierende 10-Punkte-Plan zur Umsetzung der IT-Sicherheit in der Produktion schließt den Beitrag ab.
Evaluation of accuracy of medical optical navigation system “Neuroplan” for modeling of neurosurgical interventions
Authors: Arhipov I. V. , Mikhaylov E. M. , Dolotova D. D. , Zakondyrin D. E. , Gavrilov A. V. , Leychenko A. I. , Krylov V. V. , Dmitriev A. Yu.
Published: January 2019

This study is devoted to the accuracy of the optic navigation system “Neuroplan”. To assess the complex error of the system, a plastic model of the skull with 8 radiocontrast target points was developed. Twelve neurosurgeons with different levels of training participated in the study. The design of the study provided for each doctor performance of registration in the “Neuroplan” system at various positions of the model with subsequent hit at the target points. To select the optimal method of registration for different patient positions on the operating table, the registration table for anatomical landmarks (from 3 to 7) and on the surface was used. The analysis of the obtained results showed a high accuracy of the optic navigation system “Neuroplan”: in the side position of the scull model the target error averaged 1.57 [1.11; 2.13] mm, in the face down position – 1.69 [1.26; 2.19] mm, which is comparable with the declared accuracy of foreign analogues. When the experiment was repeated, it was shown that the system has high retest reliability.
Surgical treatment of malignant cerebellar infarction
Authors: Dashyan V. G. , Khodykin E. A. , Nikitin A. S. , Godkov I. M. , Sytnik A. V. , Khovrin D. V. , Sosnovskiy E. A. , Asratyan S. A. , Lukyanov A. L. , Sharifullin F. А.
Published: January 2019

The study objective is to evaluate the effectiveness of various methods of surgical treatment of malignant cerebellar infarction.

Materials and methods. There were 47 patients with malignant cerebellar infarction retrospectively analyzed in this study. The group 1 included all patients who underwent surgical treatment (n = 31), the group 2 included all patients who underwent conservative treatment (n = 16). In the group 1, 15 patients underwent isolated ventriculostomy, 4 – posterior fossa decompression (PFD), 14 – combination of ventriculostomy and PFD. The criteria of efficacy of surgery were: restoration of consciousness, restoration of forth ventricle and the quadrigeminal cistern configurations. Results of treatment were assessed according to the Glasgow outcome scale.

Results. The recovery of consciousness level was observed in 7 out of 15 patients after isolated ventriculostomy on average 13 day; the efficacy was 47 %. Four patients underwent only PFD. Among them 2 patients needed additional external ventricular drainage installation as 2nd operation. The efficacy was 50 %. After PFD with simultaneous ventriculostomy the recovery of consciousness was observed on 4 day in 11 out of patients. The efficacy was 79 %. Combined ventriculostomy and PFD were 32 % more effective than ventriculostomy alone, and 29 % more effective than PFD alone.

Conclusion. In patients with malignant cerebellar infarction with a decrease in consciousness and signs of brainstem compression, ventriculostomy with PFD are advisable, because isolated ventriculostomy does not always provide a necessary effect in decompensation of dislocation syndrome.
Treatment of a pregnant woman with glioblastoma complicated by acute occlusive hydrocephalus in the subcompensation stage (from practice)
Authors: Krylov V. V. , Godkov I. М. , Grin’ A. A. , Nefedova G. А. , Кim A. V.
Published: January 2019

The study objective is to present a rare clinical observation, describe a successful 2-stage neurosurgical treatment of a pregnant patient with glioblastoma complicated by acute occlusive hydrocephalus.

Materials and methods. A pregnant woman, 36 years (pregnancy 28–29 weeks), was urgently hospitalized with a suspicion for preeclampsia at a multispecialty hospital with a maternity ward. One day prior to hospitalization the patient developed hypertensive syndrome manifesting through headache, nausea, vomiting, depressed consciousness to stupor, then seizures in the extremities with loss of consciousness.Examination had shown malignant paraventricular tumor of the left temporal and parietal lobes accompanied by perifocal edema, brain dislocation, and acute occlusive triventricular hydrocephalus.

Results. Treatment included the following stages: 1) emergency endoscopic third ventriculocisternostomy under local anesthesia, 2) premature delivery per cesarean section, 3) microsurgical resection of the brain tumor. Histological examination diagnosed glioblastoma (grade IV). The patient was discharged with minimal neurological deficiency (elements of motor and sensory aphasia) for administration of chemoradiation therapy.

Conclusion. Surgical treatment of a patient with glioblastoma and acute occlusive hydrocephalus in the 3rd trimester can be performed safely and effectively for the mother and fetus in 2 stages. Third ventriculocisternostomy under local anesthesia is recommended as a method of cerebrospinal fluid drainage.
Intraoperative neurophysiological monitoring during thoracoscopic removal of the paravertebral spinal tumor (from practice)
Authors: Grin’ A. A. , Sinkin M. V. , Aleynikova I. B. , Kordonskiy А. Yu.
Published: January 2019

Bol’shaya Sukharevskaya Sq., Moscow 129090, Russia

The study objective is to describe the clinical case of intraoperative neurophysiologic monitoring (IONM) using the electromyography-triggered stimulation during the thoracoscopic removal of an extradural Th2–Th3level tumor.

Materials and methods. The case describes the removal of the right Th2–Th3pleural cavity paravertebral tumor that has compressed the phrenic nerve. The patient underwent thoracoscopic surgery supported by IONM. An electromyography-triggered stimulation with a monopolar stimulator that was inserted through the thoracoscopic access into the thoracic cavity under video control identified the phrenic nerve. 

Results. The thoracoscopy in combination with electromyography-triggered stimulation allowed to avoid open surgery. The use of traditional IONM for spinal surgery would not identify the diaphragmatic nerve and prevent its unintentional damage.

Conclusion. IONM scenarios can be successfully enhanced with a electromyography-triggered stimulation of the phrenic nerve. Adhesive disposable electrodes for muscle response recording and stimulus return are useful without any deterioration of informativity.
Aneurysms of the pericallosal artery (literature review)
Authors: Grigoryev I. V. , Sen’ko I. V.
Published: January 2019

The study objective is to analyze scientific sources describing features of surgical treatment of aneurysms of the pericallosal artery (APcA) and unfavorable outcome risk factors.

Materials and methods. The analysis included 4 russian and 57 foreign sources.

Results and conclusion. Conservative treatment of patients with ruptured APcAs yields unsatisfactory results due to high mortality. Data on surgical outcomes of ruptured APcAs are contradictory: per some sources, they do not differ from results of treatment of cerebral aneurysms of other locations; another sources state that they are worse. The main risk factors are severity per the Hunt–Hess scale ≥IV, large size of intracranial hematoma. Outcomes of surgical treatment of unruptured aneurysms are mostly favorable. Microsurgical clipping allows to achieve favorable results both for ruptured and unruptured APcAs. Due to deep APcA localization, the majority of revascularization surgeries can be performed only using intracranial-to-intracranial bypass. Extracranial-intracranial bypass in the anterior cerebral artery system is rarely performed. For surgical treatment, choice of its timeframe in critically ill patients (grade IV–V by the Hunt–Hess scale) causes difficulties: early surgery prevents repeated hemorrhages, while postponed surgeries eliminate the possibility of affecting this and other factors. There are arguments for preventive exclusion of APcA from blood flow even if its size is <5 mm because of high frequency of APcA ruptures and more severe consequences. For combination of an unruptured APcA with a ruptured aneurysm in another location, either simultaneous exclusion of all aneurysms is performed or two-stage surgery with primary exclusion of the ruptured aneurysm, but the first approach is not always possible. Selection of optimal approach depends on the location of the aneurysm: pterional approach is used for clipping infracallosal aneurysms, variations of interhemispheric accesses – for exclusion of supracallosal aneurysms and aneurysms located at the genu of corpus collosum. Temporary pharmacological cardioplegia is considered a promising method which potentially can replace temporary APcA clipping.
Restoring voice function after open diagonal resection of the larynx
Authors: Kozhanov A. L. , Kozhanov L. G. , Sorokin V. N. , Romanova E. S.
Published: January 2019

The study objectiveis to perform the acoustic analysis of voice in patients after open diagonal resection of the larynx.

Materials and methods. A total of 112 patients underwent diagonal resection of the larynx; of them 73 hadfrontolateral resection and 39 had expanded frontolateral resection. Primary laryngeal cancer was diagnosed in 107 patients; five patients had relapses after radiation therapy. Fifty-six participants underwent acoustic analysis of voice before surgery, 52 participants underwent it 1 month postoperatively, and 112 participants had it after completing their rehabilitation (6 months to 10 years postoperatively). To determine normal acoustic characteristics of voice, we examined 80 men with normal voice. We measured voice fundamental frequency (FF), maximum and minimum FF, FF variability, jitter, shimmer, voice intensity, amplitude of fundamental tone’s harmonics and their difference. Speech rehabilitation included breathing exercises according to E. Ya. Zolotareva and speech training according to S.L. Taptapova.

Results.Patients with laryngeal cancer demonstrated significant changes in the acoustic characteristics of their voice (p <0.05) compared to healthy individuals, including increased mean FF (f0) (up to 143 ± 45 Hz vs 118 ± 18 Hz in controls), decreased voice intensity (from 60 ± 8 to 43 ± 8dB), and almost 2-fold decrease in the amplitude of fundamental tone’s harmonics (ω0, 2 ω0, 3 ω0). We also found an increased dispersion and variability of acoustic characteristics assessed compared to healthy individuals. The analysis of long-term treatment outcomes demonstrated more significant improvement of voice acoustic characteristics in patients who underwent speech rehabilitation compared to those who had no rehabilitation.

Conclusion.Open resection of the larynx with endoscopic removal of granulations and ligatures and laser restoration of the laryngeal lumen by dissecting the scars complemented by speech rehabilitation allow restoring respiratory function in 91.1 % of patients and restoring voice in 91.8 % of patients (to achieve acoustic characteristics close to normal).
Depression is not the only cause of cognitive impairment in chronic migraine
Authors: Latysheva N. V. , Filatova E. G. , Osipova D. V.
Published: January 2019

Background. Patients with the chronic migraine frequently present with memory and attention complaints. However, the prevalence and phenotype of such impairment in chronic migraine have not been studied.

Objective – to evaluate the prevalence of the objective cognitive deficit in patients with chronic migraine and factors underlying its etiology.

 Materials and methods. We recruited 62 subjects with chronic migraine and 36 genderand age-matched controls with low-frequency episodic migraine (not more, then 4 headache days per month) aged 18–59. All patients filled in the Hospital Anxiety and Depression Scale (HADS) and Sheehan Disability Scale. Cognitive function was assessed with the Montreal Cognitive Assessment (MoCA), Digital Symbol Substitution Test (DSST), Rey Auditory Verbal Learning Test (RAVLT), and the Perceived Deficits Questionnaire (PDQ-20).

Results. In this study 58 % of patients with chronic migraine complained of memory loss. Cognitive impairment was also found with PDQ-20. Objectively, we found a significant decrease in 90-second DSST results and RAVLT total recall and learning rate. In 40 % of subjects with chronic migraine scored lower than 26 points on MoCA. Patients with chronic migraine more frequently had lower DSST rates as compared to episodic migraine (odds ratio 5.07 (95 % confidence interval – 1.59–16.17); p = 0.003). Depression and anxiety did not correlate with performance on cognitive tests. Chronic migraine (frequent headache) and longer headache history, but not depression, anxiety or medication overuse were independent predictors of cognitive impairment.

Conclusion. Subjective and objective cognitive deficits are prevalent in the chronic migraine population. Most often memory and attention are impaired. Longer headache history and presence of chronic migraine are independent risk factors for cognitive impairment in patients with chronic migraine.
TRANSRADIAL APPROACH FOR CAROTID ARTERY STENTING
Authors: Malaev D. U. , Kretov E. I. , Baystrukov V. I. , Prokhorikhin A. A. , Boykov A. A.
Published: January 2019

Approximately 20% of ischemic strokes are provoked by stenotic carotid artery lesions. With the growing experience of surgeons and the continued improvement of devices, carotid artery stenting has become an effective alternative to carotid endarterectomy. Traditional access to carotid artery stenting is transfemoral approach. However, due to peripheral artery disease and challenging anatomy of the aortic arch, transfemoral approach may be problematic. A number of randomized trials have proven the effcacy and safety of transradial access for coronary interventions. A similar technique was adapted for coronary artery stenting. The article provides a review of the major studies dedicated to coronary artery stenting via transradial approach, discusses all benefts and limitations as well as provide the guide to select an optimal vascular access, depending on the patient's anatomical characteristics. Transradial approach is shown to be a good alternative to transfemoral approach for coronary artery stenting. However, it is accompanied by a high rate of unsuccessful procedures compared to transfemoral approach. Nevertheless, transradial approach is accompanied by a decrease in the rate of vascular complications, and is preferable for intervening on the right ICA, or on the left with bovine aortic arch.
FACTORS ASSOCIATED WITH THE PREVALENCE OF ARTERIAL HYPERTENSION IN THE GENERAL WORKING AGE POPULATION
Authors: Kaveshnikov V. S. , Serebryakova V. N. , Trubacheva I. A.
Published: January 2019

Aim.To determine the factors associated with the prevalence of arterial hypertension (AH) in the unorganized urban population of working age.

Methods. Random sample drawn from adult urban population aged 25–64 years (n = 1600, 59%-women) was examined in the standardized cardiologic screening program. The following associative factors were analyzed: age, family status, level of education and income; excessive salt consumption (ESC), low physical activity, alcohol consumption; family history of AH; anxiety/depression (HADS); smoking, body mass index (BMI), heart rate (HR). Logistic regression was used to analyze the relationships. A p value of <5% was considered statistically signifcant.

Results.After adjustment for age, the odds for AH were higher in men (OR = 1,57, p<0,001) with the maximum gender effect found in 35–44 years (OR = 3,66, p<0,001). In the singlefactor analysis, age, BMI, family history of AH, HR and ESC were the most signifcant risk factors for AH in men. Secondary education and clinical anxiety in addition with the above-mentioned ones increased odds for AH in women. In the multivariable model, age, BMI, family history of AH and HR were associated with high AH prevalence in men. In women, these factors included age, BMI, family history of AH, HR, ESC, middle education and clinical anxiety. Out of the other modifable risk factors, BMI contributed greatly to the variability in AH prevalence in the examined population.

Conclusion.The obtained fndings provides novel data on the comparative signifcance of the studied risk factors. The efforts to prevent excessive weight gain and dietary salt consumption seem promising to reduce AH prevalence in the population. Further studies focusing on the role of genetic, behavioral, and environmental factors for AH development will ensure the establishment of more effective, accurate and personalized prevention approaches in the future.
Clinical approbation of biologically active supplement in patients with vegetovascular dystonia
Authors: Vekovtsev A. A. , Podzorova G. A. , Poznyakovsky V. M.
Published: January 2019

Aim. To study the possibility of using and estimate the efficiency of a new tablet form of biologically active supplement in patients with vegetovascular dystonia syndrome.

Materials and methods. One hundred patients with vegetovascular dystonia syndrome, including 50 patients of the main group and 50 patients of the control group were examined. There is presented the composition of prescription formula of biologically active supplement, based on participation of its components in the correction of disturbed metabolic processes of the nervous system.

Results. Additional application of biologically active supplement in combination with drug significantly improves cerebral blood flow, decreases blood viscosity and risk of cellular membrane impairment, normalizes arterial pressure, elevates initiative and attention, reduces headache in patients of the main group with vegetovascular dystonia syndrome.

Conclusions. Use of biologically active supplement has a positive effect in complex therapy of patients with vegetovascular dystonia syndrome.
Conservative-and-preventive stomatology: modern trends of development
Authors: Gileva O. S.
Published: January 2019

The paper presents a detailed analysis of global trends and subtrends of modern conservative-and-preventive stomatology, based on survey-analytical methods of study in interconnection with performed earlier, realized nowadays and planned scientific and practical elaborations of Perm therapeutists-stomatologists school.
Microtonal Analysis of "Blue Notes" and the Blues Scale
Authors: Cutting Court B
Published: January 2019

Microtonal evaluation of blue notes in the early blues scale by empirical pitch measurement and statistical characterization has not yet been performed in existing research. To address this, fifteen recorded classic blues performances by acknowledged early masters of the blues were studied. Computer based methods were used to collect the audio frequencies of note samples from each performance. Each note had its frequency ratio with respect to the average tonic tone for the performance converted to microtonal cents format. Cluster analysis was performed on these note collections to identify individual note clusters. The fourth and fifth were clearly identified. Three principal "blue note" clusters were isolated with means of 319.1, 582.8, and 1037.9 cents. These values corresponded closely to the harmonic half diminished seventh chord (i.e. 1, ♭3, ♭5, ♭7 with harmonics 5:6:7:9). The "neutral" third was confirmed to occur in this sample. A similar blending of the perfect fourth and tritone was demonstrated in this study. The flat 7th presented as three separate clusters. Several clusters idiosyncratic to individual performers were also identified. Findings are discussed with regards to the array of theories proposed to explain the blues.
Turcot Syndrome: A Synchronous Clinical Presentation of Medulloblastoma and Lower Rectal Tumor
Authors: BORNI Mehdi , Kolsi Fatma , Kammoun Brahim , Boudawara Mohammed Zaher
Published: January 2019

We report the case of a 16-year-old patient who was operated for medulloblastoma with simple operative followup after radio and chemotherapy. Two years later, she was admitted, in a state of cachexia, for abdominal pain and rectorrhagia. The explorations found an infected lower rectal tumor. The patient underwent an urgent surgery. Immediate consequences were marked by the installation of a severe septic shock causing the patient’s death.
Calf Muscle Pump Stimulation Increases Lower Limb Bone Density in Perimenopausal Women
Authors: McLeod Kenneth James , Pierce Carolyn
Published: January 2019

Nutrient delivery to bone tissue, as for all tissues in the body, is provided through interstitial fluid flow. This flow is driven by the differential fluid pressures between the intramedullary canal and the tissues outside of the bone. Correspondingly, reductions in tissue fluid pressure should enhance interstitial bone fluid flow, nutrient delivery, and thereby increase bone mineral density. This hypothesis was tested in a one year long pilot clinical study of healthy, employed, perimenopausal women (42 - 68 years). Soleus muscle (calf muscle pump) stimulation was utilized with the intent of increasing lower limb fluid return to the heart, serving to both reduce lower limb tissue pressures and to increase intramedullary pressures by increasing cardiac output. Dual-energy x-ray absorptiometry (DXA) assessments of bone mineral density (BMD) were obtained at 12 month intervals. Muscle stimulation usage ranged from 0.7 to 4.8 hours/work-day. Dose dependent responses between duration of daily soleus muscle stimulation and changes in both proximal femur BMD (+0.5% per hour of daily use; p = 0.05) and proximal tibia BMD (+1.5% per hour of daily use; p = 0.0004), were observed; no significant effect was observed at the lumbar spine. These results are consistent with the hypothesis that calf muscle pump stimulation, which is sufficient to reduce lower limb fluid pooling, is capable of significantly reducing the rate of bone loss in perimenopausal women as well as enhancing new bone formation.
Increased Total Serum Immunoglobulin E in Children Developing Mycoplasma pneumoniae-related Extra-pulmonary Diseases
Authors: Poddighe Dimitri , Comi Elena Virginia , Brambilla Ilaria , Licari Amelia , Bruni Paola , Marseglia Gian Luigi
Published: January 2019

Mycoplasma pneumoniae has been recognized to be involved in several extra-pulmonary diseases, but the underlying immunologic mechanisms are still largely unknown. Recently, we observed a significant elevation of serum Immunoglobulin E (IgE) in a small group of these children. Here, we assessed total serum IgE levels in children affected with Mycoplasma pneumoniae-related extra-pulmonary diseases.
We prospectively collected the data of 162 children admitted to the hospital (because of respiratory infections or extra-pulmonary diseases) who were evaluated for Mycoplasma pneumoniae serology and total serum IgE levels, concomitantly. Based upon clinical and serology aspects, 3 groups of children were identified: I) with non-mycoplasma respiratory disease; II) with mycoplasma-related respiratory diseases; III) with extra-pulmonary diseases related to concomitant/recent Mycoplasma pneumoniae infection. Interestingly, children with Mycoplasma pneumoniae-related extra-pulmonary diseases showed a significant elevation of total serum IgE.
In particular, patients developing Mycoplasma pneumoniae-related extra-pulmonary diseases (group III) showed significantly higher level of IgE than both previous groups (p<0.001 vs. group I; p<0.01 vs. group II).
In conclusion, hospitalized children diagnosed with Mycoplasma pneumoniae-related extra-pulmonary diseases resulted to have significantly increased serum IgE compared to children developing respiratory illnesses only.
Sensitization and Geographical Distribution of Main Aeroallergens in Iran
Authors: Teifoori Fardis , Postigo Idoia , Abtahi Mohammad , Dehghani Mehdi , Martinez Jorge
Published: January 2019

Aeroallergens are one of the most important environmental factors that induce allergic reactions in sensitized population. Pollen grains, molds, house dust mites, and animal dander are of major concern because of their abundant sources and ubiquitous presence in environments. Identifying the allergens in geographical areas plays an important role in the diagnosis; prevention and management of allergic disorders. Here, we discussed the most common aeroallergens in Iran and suggested appropriate preventive strategies to decrease the morbidity of allergic patients. The sensitivity to the most common aeroallergens affecting Iranian population is summarized in Table 1. Further delineation of these factors is provided below
Comparison of the Cox Semi-Parametric Model and Parametric Models in Analyzing the Effective Diagnostic Factors in Kidney Transplantation Survival
Authors: Askarishahi Mohsen , Atapoor Abdolamir , Hemayati Roya , Shahidi Shahrzad , Zeynali Sajedeh
Published: January 2019

Introduction: Kidney transplantation is the best treatment for patients with advanced kidney diseases. The aim of this study was to determine the rate of transplanted kidney survival and compare the efficiency of Cox semi-parametric model with the parametric models in determination of survival effective factors.
Method: This is a historic cohort study including the information of 381 ESRD patients, who underwent kidney transplant surgery from December 2007 to March 2016 in Noor hospital of Isfahan, Iran. In order to identify the effective factors in transplantation survival, the parametric and semi-parametric models were fitted with data and Akaike informationcriterion was used for detecting the most efficient model. Data analysis was carried out with R software, Version 3.1.0 at thesignificance level of 0.05.
Results: According to the Kaplan-Mayer method, 1-, 3-, 5-, and 8-year survival rates of transplanted kidney were estimated as 0.987, 0.933, 0.869, and 0.839, respectively. Multi-variable analysis of all fitted models indicated that the duration of dialysis before transplantation (P ≤0.05) and the level of creatinine at the time of discharge from hospital (p≤0.05) had significant relationship with survival of transplanted kidney. Akaike values of Cox, Weibull, exponential, lognormal, and log-logistic models were calculated as 484, 484, 482, 484, and 356, respectively.
Conclusion: Based on the Akaike information criterion, the Cox semi-parametric model was selected and proposed as the superior model.
The Relationship of Smoking, Alcohol, and Drugs Consumption on the Quality of Semen Parameters in Males referring to the Infertility Center of Yazd in 2016
Authors: Shafabakhsh Marjan , Sadeghian HosseinAli , Ehramposh Mohammad Hassan , Aflatonian Abas , Dehghani Arefeh , Taghi Ghaneian Mohamad
Published: January 2019

Introduction: Male infertility has increased during recent years in countries of the world including Iran. Among many factors that influence the infertility, smoking, alcohol, and addictive drugs were investigated in this study.
Methods: This case-control retrospective study was conducted on 600 male patients consisting of 300 individuals with natural semen and 300 people with defective semen. The first step in investigation of infertility in each couple was to conduct a spermogram to detect the male infertility. The case group included men who referred to the Yazd Infertility Treatment Center and had at least one abnormal test result among considering the parameters of semen test. The control group included the men who referred to the same center and had normal semen test result. The data collection tools were a researcher-made checklist based on the parameters required for the study with epidemiological and observational design, as well as the semen analysis test. 
Results: The age mean in the case and control groups were 34.71 and 33.82 years with the standard deviation of ± 7.3 and ± 6.41, respectively. The means of marriage age in the case and control groups were 26.28 and 26.28 ±5.3 years, respectively. The mean duration of infertility in the case group was 6.30 ± 4.60 and in the control group was 5.15± 3.88. No significant difference was observed between the mean age (P = 0.084) and marital age (P = 0.448) in two groups, but the mean duration of infertility (P <0.001) was significantly different between the two groups .The prevalence of smoking was significantly different between the two groups (P = 0.032). Considering the daily frequency of smoking, the highest rate was 11-20 cigarettes in both groups (case group 21.7% and control group 15.3%). The P value was set at 0.018.
Conclusion: In this study, smoking and consumption of alcohol were not considered as the predictive factors of semen quality, but  consumption of drugs and the age of starting consumption of drugs had a significant relationship with the semen disorders.
Knowledge, Attitude, and Practice toward Protection of Cooling Systems (Refrigerator and Freezer) and Control of Ozone - Depleting Gases Emission into the Environment among Health Volunteers in Yazd
Authors: Rezaeipandari Hassan , Amanalikhani Shabnam , Ghaneian Mohammad Taghi , Amrollahi Mohsen , Soltanianzadeh Zahra
Published: January 2019

Introduction: Chlorofluorocarbons are one of the most important ozone-depleting substances used as coolant gases in refrigerators and freezers in developing countries such as Iran. The objective of this study was to determine the knowledge, attitude, and practice toward the protection of cooling systems and control of ozone-depleting gases emission into the environment among health volunteers in Yazd city, Iran.
Methods: This descriptive and cross-sectional study was conducted on 110 health volunteers in Yazd in 2014. The data collection tool was a researcher-made questionnaire containing  four parts of demographic data, knowledge, attitude, and practice of health volunteers. The data were analyzed by descriptive tests, ANOVA, and Pearson correlation.
Results: The mean scores of knowledge, attitude, and practice of health volunteers were 8.12 ± 4.02 (range 0-23), 66.82 ± 7.55 (range 19-95), and 8.21 ± 1.47 (range 0-12). A positive and significant correlation was also observed between the three variables of knowledge, attitude, and practice of volunteers regarding the protection of cooling systems and controlling the emission of ozone-depleting gases into the environment (p <0.05).
Conclusion: The knowledge of health volunteers, as an effective stratum in the knowledge, attitude, and practice of the community, about depletion of the ozone layer, as one of the most important environmental issues, was not at an appropriate level. Therefore,  educating and promoting the knowledge level of health volunteers is of great importance  as the most basic part of making health behaviors.
Landmarks with questions – England's school history wars 1967-2010 and 2010-2013
Authors: Guyver Robert
Published: January 2019

This is in two parts and provides a background to national curriculum developments mainly from 1967 to 2010 as well as a focus on debates since 2010. It seeks to make links between previous curriculum debates and the current ones in the areas of pedagogy, method and content. The earlier
debates had features of many issues that would arise again in the 2010-2013 period, especially: quantitative versus qualitative approaches to education; the place of nation vis-a-vis the rest of the world; the relationship between a disciplinary approach and substantive contexts; the role
of historians, government and professional associations; and the role of the media. Progress in planning for the 2013 draft history curriculum in England has been slow, but the nature of the speculation before, and of the reaction after the publication of the draft shows that there are some
strongly held and deeply entrenched positions about what function a national history curriculum should fulfil. The debate has involved a Government Minister (Michael Gove) and a range of teachers and academics, and – particularly – historians: from the celebrity academics chosen
by him to advise, to others whose response has been divided but public, involving letters and articles in the media. A major concern has been how to organise and rationalise for an English curriculum a national narrative for students 7-14 that encompasses not only a disciplinary approach but
also both British and international contexts. Complaints from all groups however show disappointment that the Minister failed to secure his earlier interest in extending compulsory school by two years to the age of 16.
'A Giant with Clay Feet': Quebec Students and their Historical Consciousness of the Nation
Authors: Lévesque Stéphane , Létourneau Jocelyn , Gani Raphaël
Published: January 2019

The aim of this paper is to explore French Canadian (Québec) students' historical consciousness of the nation through the lens of Social Identity Theory (SIT). Relying on a sample of 142 Quebéc's historical narratives written by Francophone Québécois students,
the paper revisits findings from a previous study on the historical consciousness of young Québécois. Informed by SIT principles, our narrative analysis shows how most Franco-Québécois categorize the past in homogenous categories (e.g., the imperialist Anglophone;
the surviving Francophone) and frame their stories into particular modes of present-day orientations. Implications of this studyfor history education are also discussed.
History Teaching in the Republic of Korea: Curriculum and Practice
Authors: Kang Sun Joo
Published: January 2019

In the Republic of Korea, many history education professionals have focused on what is meant by, and how to develop, students' understanding of the discipline of history while the lay public has been focused on what students should know about the past by the end of their school courses.
This article discusses issues around history curriculum and teaching and learning practice in the Republic of Korea. It introduces some Korean research trends in history thinking and students' understanding of history. It also presents issues of historio-graphical disputes among Korea, China
and Japan and cultural conflicts between Korean neo-conservative and neo-progressive around national history curriculum.
Los mecanismos de corrección de los conflictos de interés de los administradores societarios
Authors: Berrocal Mora María de los Ángeles
Published: January 2019

Los administradores de todas las sociedades comerciales deberán actuar, durante toda la vigencia del cargo, cumpliendo con el lleno de los deberes y obligaciones contenidos en la Ley 222 de 1995, de lo contrario, estarán sujetos a los diferentes regímenes de responsabilidad.
IDENTIFICATION OF HUNTETE BEACH TOURISM OBJECT IN KULATI VILLAGE EAST TOMIA SUB-DISTRICT WAKATOBI REGENCY
Authors: Sejati Andri Estining , Amaluddin La Ode , Ihsan Fahrudi Akhwan , - Mutiana
Published: January 2019

Huntete Beach has good physical potention, but still not optimal visitors. The purposes of this paper there are two (a) to determine the potention of Huntete Beach tourism objects in Kulati Village, East Tomia Subdistrict, Wakatobi Regency, (b) To find out the perception of tourists on the potential of Huntete Beach tourism objects in Kulati Village, East Tomia District, Wakatobi Regency. This research uses survey method. The results of this paper are (a) the potential of Huntete Beach is in the medium category (internal potential) and low (external potential), so it needs to be developed again so that it can become a main tourism object in East Tomia Subdistrict, Wakatobi Regency, (b) Presumption from tourists who visit that there is a potential in Huntete Beach tourism, so needs better management by completing facilities that are not yet available. It can tourists more enjoy the natural phanorama and not feel bored at this place.

Keywords: potential identification, tourism object, Huntete beach
Aprendizagem e desenvolvimento profissional de professores iniciantes que participam de comunidades investigativas
Authors: Losano Ana Leticia
Published: January 2019

Os primeiros anos de exercício profissional nas escolas constituem uma etapa conflitiva, marcada por tensões e contradições entre princípios, ideais e experiências vividas durante a formação inicial e demandas, desafios e restrições da prática docente nas escolas. Nesse cenário, o presente artigo visa descrever e compreender a aprendizagem e o desenvolvimento profissional de professores iniciantes que participam de comunidades investigativas. A pesquisa toma por foco um grupo colaborativo formado por seis professores iniciantes e duas professoras universitárias. Utilizando uma metodologia qualitativa, o estudo desenvolve uma análise narrativa que detalha e analisa episódios que envolveram os membros da comunidade no planejamento, na implementação em sala de aula e na reflexão de uma tarefa centrada na interpretação de gráficos. O resultado evidencia as potencialidades da participação em comunidades investigativas para a aprendizagem e o desenvolvimento profissional dos professores iniciantes.
Processo formativo do aluno em matemática
Authors: Azevedo Greiton Toledo , Maltempi Marcus Vinicius , Lyra-Silva Gene Gene Maria Vieira
Published: January 2019

Este trabalho busca compreender o processo formativo de alunos da Educação Básica para além das práticas usuais de sala de aula de matemática, envolvendo a produção de jogos digitais e seu uso com pacientes de Parkinson. Tal iniciativa foi realizada no âmbito do Projeto de extensão Mattics, do Instituto Federal Goiano, Campus Avançado Ipameri, em uma escola pública da região metropolitana de Goiânia, norteada pela pesquisa qualitativa. Os dados produzidos foram analisados a partir de elementos do Construcionismo e do Turbilhão de Aprendizagem identificados nas atividades mobilizadas além dos aspectos sociais e humanos tecidos ao longo da formação do aluno. Os resultados obtidos com a análise de dados indicam elementos do ambiente criado que atuam como contexto e motor para a produção de significados em matemática pelos alunos, evidenciando a relevância de uma formação contextualizada e atuante.
Ensino de Matemática na EJA: Betim (MG), década de 1990
Authors: Ferreira Ana Rafaela Correia , Gomes Maria Laura Magalhães
Published: January 2019

Este artigo focaliza o ensino de Matemática na Educação de Pessoas Jovens Adultas e Idosas (EJA), no curso de Suplência oferecido pela Rede Municipal de Educação de Betim, Estado Minas Gerais, entre 1995 e 1999. A fonte principal do estudo é constituída por entrevistas realizadas com oito educadores, com a utilização da História Oral como princípio teórico-metodológico. Três seções inter-relacionadas compõem a parte central do texto: a questão da relação entre o tempo disponível e o currículo da EJA, as motivações para a seleção do que seria ensinado e os conteúdos matemáticos efetivamente propostos e trabalhados. Como principais critérios norteadores, evidenciaram-se a intenção de apresentar a Matemática de forma contextualizada na vida social e em outras áreas do conhecimento; a abreviação do tempo de curso em comparação ao ensino regular, a perspectiva de continuidade dos estudos para os alunos. Na análise dos depoimentos dos entrevistados, abordam-se diversos aspectos, como a falta de materiais didáticos projetados especificamente para a EJA, as dificuldades dos estudantes em Matemática, as carências dos docentes no sentido de atender as particularidades dos sujeitos jovens, adultos e idosos.
Uji Aktivitas Antibakteri Salep Ekstrak Etanolik Daun Binahong (Anredera cordifolia (Ten.) Steenis) Dengan Berbagai Variasi Basis Terhadap Bakteri Staphylococcus aureus
Authors: Zulfa Elya , Prasetyo Tegar Bagus , Murrukmihadi Mimiek
Published: January 2019

ABSTRAK

Salep ekstrak etanolik daun binahong (Anredera cordifolia (Ten.) Steenis) basis absorpsi memiliki aktivitas antibakteri terhadap Staphylococcus aureus pada konsentrasi 10%. Dalam meningkatkan aktivitas zat aktif ekstrak etanolik daun binahong, maka perlu dilakukan penyesuaian berbagai basis formulasi salep. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri salep ekstrak daun binahong dengan variasi basis hidrokarbon, absorpsi, dan larut air terhadap Staphylococcus aureus.Ekstrak etanolik daun binahong diperoleh dengan metode maserasi menggunakan etanol 70%. Salep dibuat dengan variasi basis pembawanya yaitu hidrokarbon, absorpsi, dan larut air. Salep yang telah dihasilkan selanjutnya diuji aktivitas antibakterinya terhadap bakteri Staphylococcus aureus. Data hasil uji aktivitas antibakteri dianalisis secara Anova satu jalan dan dilanjutkan Tukey dengan taraf kepercayaan 95%. Hasil uji aktivitas antibakteri salep ekstrak etanolik daun binahong (hidrokarbon, absorpsi, dan larut air) tidak memiliki perbedaan yang bermakna (Sig≥0,05).
Kata Kunci : Salep, Daun binahong, Aktivitas antibakteri, Staphylococcus aureus.

ABSTRACT

The absorbtion-based ointment of ethanolic extract of binahong leaves (Anredera cordifolia (Ten.) Steenis) on 10% concentrate has antibacterial activity towards Staphylococcus aureus. In order to improve the activity of this ethanolic extract of binahong leaves, it is necessarily to adjust the ointment’s base of formulation. The aims of study are to determine the ointment’s physical characteristics as well as the antibacterial activity towards Staphylococcus aureus which various base such as hydrocarbon, absorbtion and water solubility. The ethanolic extract of binahong leaves obtained from maceration method using 70% of ethanol. The ointment was made based on the variation of its base which are hydrocarbon, absorbtion and water solubility. The obtained oinment then was examined on antibacterial activity toward Staphylococcus aureus. Anti-bacterial activity were analyzed using one-way ANOVA and Tukey with the level of confidence up to 95%. the antibacterial activity of ethanolic extract ointment of binahong leaves (hydrocarbon, absorbtion, and watersolubility) also did not have any significant differences (Sig≥0,05).

Keywords: Ointment, Binahong leaves, Antibacterial activity, Staphylococcus aureus.
Pengaruh Pemberian Edukasi Gaya Hidup terhadap Peningkatan Pengetahuan Karyawan Obesitas di Universitas X
Authors: Atmaja Dewi Susanti , Rinda Agnes Christie
Published: January 2019

ABSTRAK

Prevalensi obesitas beberapa tahun terakhir mengalami peningkatan dan menyebabkan risiko berbahaya bagi kesehatan. Edukasi gaya hidup merupakan salah satu bentuk pendekatan terapi yang tepat bagi penderita obesitas karena dapat meningkatkan pengetahuan sehingga memiliki kontribusi bagi pencegahan dan penatalaksanaan obesitas. Penelitian ini bertujuan untuk melihat pengaruh edukasi gaya hidup terhadap peningkatan pengetahuan penderita obesitas. Desain penelitian adalah kuantitatif dengan metode before-after study untuk menguji efektivitas dari edukasi gaya hidup terhadap peningkatan pengetahuan penderita obesitas. Subyek adalah karyawan Universitas X yang menderita obesitas tingkat I berjumlah 28 orang. Subyek akan menerima intervensi edukasi gaya hidup sebanyak tiga kali pertemuan (seminggu sekali). Variabel yang diukur adalah peningkatan pengetahuan subyek. Pengukuran dilakukan sebelum dan sesudah pemberian edukasi. Terdapat perbedaan signifikan sebelum dan sesudah edukasi pada tingkat pengetahuan subyek (p=0,00). Pemberian edukasi gaya hidup berpengaruh terhadap peningkatan pengetahuan penderita obesitas.

Kata kunci: Edukasi, gaya hidup, obesitas, pengetahuan

ABSTRACT

Obesity prevalence has increased in the last few years and has caused dangerous risks for health. Lifestyle education is one of suitable therapy for obesity patients because it can increase knowledge and thus contribute to the prevention and management of obesity. This research aimed to see the impact of lifestyle education to increase the knowledge of obesity patients. The design of this research is quantitative using before-after study method to analyze the effectiveness of lifestyle education to increase the knowledge of obesity patients. The subjects are 28 sedentary men workers of University X with obesity I category. The subject were given 3 times lifestyle education intervention (once a week). The measured variable is the increased knowledge of the subject. All measurements had been done before and after education given. There is a significant difference before and after education at the level of knowledge of the subjects (p = 0.00). Provision of education on lifestyles affects the increased knowledge of obesity patients.

Keywords: Education, lifestyle, obesity, knowledge