bluuebunny/crossref_metadata_2025 huggingface dataset:
Genrogenic situations (on the example of boltovnya ‘≈chatter’)
Authors:   Saratov State University, Dementyev Vadim V.
Published: June 2024

The article deals with genrogenic situations (GgS), i.e. situations marked by speech genres, indicative of the representation of a particular speech genre in a given national culture. The G gS as a cognitive image corresponding to a speech genre in the human mind includes, on the one hand, a set of components of a communication situation, necessary and sufficient for the generation of this genre, and, on the other hand, the memory of the GgS, real or reconstructed (by writers, psychologists), in which this genre was generated and developed. These factors determine the theory and practice of speech genres methodology based on GgS: it, unlike the theory of speech genres in general, has a more distinct applied focus: namely, it is focused on GgS and the compilation of an anthology/encyclopedia of GgS. This technique includes two aspects: firstly, a model according to which GgS are isolated from the speech continuum and systematized (GgS as a model of article structure); secondly, a model according to which speech genres are studied using the material of the GgS and taking into account their characteristics (model of filling the «body» of articles with the material). Much attention is paid to reflection (by communication specialists, word artists, journalists, bloggers) on G gS and genres themselves. The article also considers more general aspects of the GgS, their place in speech genres theory and linguistic pragmatics in general: GgS and the integral description of speech genres, GgS and genre role scenes, G gS and speech genre primary-secondary nature, GgS and the relationship between invariant and prototype approaches to the study of text and genre, GgS and speech genre variantology. As an illustration of the discussed approach the author offers GgS for speech genre boltovnya ‘≈chatter’.
Axiological characteristics of subject plots in Armenian literary fairy tales
Authors:   Pushkin State Russian Language Institute, Smolensk State University, Karasik Vladimir I.
Published: June 2024

The paper deals with evaluative characteristics of a fairy tale subject plot treated as a structure of a story about miraculous events narrated mainly to young listeners or readers in an entertaining mode and meant to form in their mind the right world view. The components of a subject plot are its motifs – consequences of actions determined by the choice made by a hero and promoting certain values, norms and practices. A literary fairy tale is an elaborated variant of a folklore story, it usually has a more complicated line of events, it is characterized by individual style of a writer in narration and evaluation of the content, and a happy end is optional in it. The fairy tales by G. Agayan, O. Tumanyan, and S. Zoryan have been analyzed. Axiological properties of these subject plots have been explained. They promote universal human values and specific features of the Armenian world view. Such specificity consists in the description of Armenian realia (nature, dress, food, etc.), the proper names which reveal the heroes characters, the description of magical creatures who inhabit the fairy tale world of Armenia and neighboring countries (mainly vishaps and devas), and in linguistic cultural concepts reflecting severe conditions of life and survival and emphasizing the importance of craft as a personal status, the warmth of family ties, critical exposure of cruel authorities and intellectual incapacity of people.
Financial frauds throughout the years – literature review
Authors: Kot Marek
Published: June 2024

Financial frauds have been a growing problem across the global financial markets. Losses generated by such illegal activities affect both the global economy and individual entities, especially those operating in the financial market. Perpetrators of such frauds seem to always be one step ahead of the law enforcement, regulators as well as private sector entities such as banks and scientists. This review examines publishing actions taken throughout the years. It also shows whether there has been any correlation spotted between the number of papers published in a particular year and the events on the financial markets.  The study involved a systematic literature review to achieve the set goals. Following the final results of the article, it is clear that the issue of financial frauds has been a growing global concern. It is crucial to strengthen the collaboration between the regulators, law enforcement, academic environment and private sector. Cooperation across the sectors should include research on how to prevent and mitigate the consequences of this kind of frauds.
Correlation Between Framework and Civil Procedural Legal Regulation
Authors:   Associate Professor of the Department of Labor, Environmental Law and Civil Procedure of the Law Institute of the Altai State University, PhD (Law), Associate Professor, Dovgan Ksenia E. , Kovalenko Natalya E. ,   Postgraduate Student of the Law Institute of the Altai State University
Published: June 2024

The study is aimed at studying the relationship between civil procedural and framework legal regulation based on an analysis of legal doctrine and current legislation. The dynamics of legal regulation are based on the modernization of methods and legal means in order to find an effective formula for legal regulation in information society. It has been determined that the main form of correlation between civil procedural and framework legal regulation is relatively specific legal norms.
Topical Issues of Qualifying Investment Partnership Relations in Notarial and Judicial Practice
Authors:   Assistant Notary of the Barnaul Notarial District, Associate Professor of the Department of Labor, Environmental Law and Civil Procedure of the Law Institute of the Altai State University, Nazemtsev Denis M.
Published: June 2024

This article analyzes the characteristics of an investment partnership agreement as a form of organizing collective investments. The author focuses on the law enforcement practice of this contractual structure, and also especially emphasizes those characteristic features that are unique to this investment instrument.
Assessing the Experiential Service Quality, Perceived Image, Experiential Satisfaction, and Revisiting Intentions of Public Zoo Visitors
Authors: Sadri Norsyafika , Yusof Ahmad Faiz Mohamad , Hanafiah Mohd Hafiz
Published: June 2024

The role of zoos in wildlife management has been revolutionized from basic conservation sites into research institutions, public education, and recreational desti-nations for public visitors. Building upon this evolution, the present study delves into the intricate interrelationships between public zoo experiential service quality, the perceived image of these institutions, experiential satisfaction, and visitors' intentions to revisit. Questionnaires were administered to 330 visitors via purposive sampling at the Kuala Lumpur National Zoo. The study hypotheses were supported, highlighting the significant and positive interrelationship between interaction quality, physical environment quality, enjoyment quality, educational quality, zoo image, experiential satisfaction, and visitor’s revisit intention. The study provides practical managerial implications for the public zoo in delivering superior services, essential in improving visitor satisfaction. Excellent service quality ensures visitor satisfaction, enabling zoo management to meet visitor's expectations and encourage return visits, thus enhancing the zoo’s sustainability. The study results urge public zoo management in developing and implementing out of the box market-orientated service strategies by enhancing the interaction, enjoyment, educational quality, and physical environment perceived by future visitors.
Development of Sustainable Integrated Farming Systems for Small and Marginal Farmers and Ecosystem Services -A Comprehensive Review
Authors: Meena L.R. , Kochewad S.A. , Kumar D. , Malik Suresh , Meena S.R. , . Anjali
Published: June 2024

This review article shows a holistic approach regarding integrated farming system (IFS) for livelihood security and sustainable development of small and marginal households in India. Integrated farming systems are being developed for location specific because enormous problems are being aroused in the agriculture and allied sectors such as declined factor productivity, profitability, unscientific management of farm resources, decreases in crops and livestock productivity due to climate change, changes in food habits of the people, deprived soil health, low inputs use efficiencies, declined in crop diversification and biodiversity, increased cost of production, utilization of high energy inputs, produces low energy outputs and other problems are also coexisted in current farming system. The integrated farming system includes different components like crops, livestock, poultry, beekeeping, fisheries, mushroom, kitchen garden, boundary plantation and others to cultivate in an integrated way for efficient utilization of limited farm resources. Moreover, imperative need to resolve these ablaze issues with the help of development of location-specific integrated farming system modules/models. IFS is a tool of sustainable strategies for the meeting of assorted agrarian anxieties along with ensured food and nutritional security and conserved ecosystem services. The standardized and upscale IFS models increased the productivity and profitability of the farmers more than mono-cropping and single-farm enterprises. The conducted studies emphases about enhance soil quality indicators, recycling and saving plant nutrients by around 55.6% through proper management of farm-based waste and byproducts. A total of 265.18 kg nitrogen, 48.91 kg phosphorus and 269.48 kg potassium can be saved through recycled farm-based waste or byproducts of a 1.5 ha model which comprises nine components. In conclusion, IFS modules/models are emission-negative or low GHG emitters, paving the way for promoting of climate-friendly farming in India. IFS emerges as a holistic approach to increase climate-resilient, greenhouse gas emissions can be reduced, it is a potential for sustainable agriculture development requiring continued research, policy support and innovative strategies for widespread adoption. As regards to livelihood security, the IFS approach has adapted to meet the home-grown family needs of cereals, pulses, oils, fruits, milk, meat, eggs, and vegetables. The future direction for research includes vertical farming, climate-smart farming systems, and improving the quality and sustainability of the farming systems, especially for underprivileged farm householders.
IMPLEMENTASI ASESMEN BERBASIS OPEN-ENDED MATHEMATICS PROBLEMS PADA SISWA SMP YANG MENDUKUNG KURIKULUM MERDEKA [IMPLEMENTATION OF AN OPEN-ENDED BASED ASSESSMENT WITH MIDDLE SCHOOL MATHEMATICS STUDENTS THAT SUPPORTS THE MERDEKA CURRICULUM]
Authors: Mulia Abigail Christina , Sa'dijah Cholis , Susanto Hery
Published: June 2024

Creativity is one of six basic principles required for the Merdeka Curriculum implementation. Not only is it realized through the Pancasila Student Profile Strengthening Project (P5), creativity also needs to be realized in learning activities. This research aims to describe the implementation of problem exercises based on open-ended mathematics problems as a form of formative assessment that supports the implementation of the Merdeka Curriculum, especially in supporting students' mathematical creativity. The research was conducted at SMP Negeri 5 Malang using the qualitative descriptive method. The research subjects were 32 seventh grade students in the 2023/2024 school year.The instruments used were question exercises and rubrics based on open-ended mathematics problems that have met the valid criteria, activity observation sheets, and student interview guidelines. The results showed that the assessment based on open-ended mathematics problems can assess the level of mathematical creativity and prompted the student’s mathematical creativity. In the implementation of assessment based on open-ended mathematics problems based on valid open-ended mathematics problems, data was obtained that the level of practicality of assessment reached a practicality score of 3,674 which means that assessment based on open-ended mathematics problems is easy to use. Based on the response questionnaire and interviews, further research is recommended to integrate open-ended mathematics problems-based assessment with gamification.

BAHASA INDONESIA ABSTRACT: Kreativitas merupakan salah satu bentuk profil pelajar Pancasila. Tidak hanya diwujudkan melalui Proyek Penguatan Profil Pelajar Pancasila (P5), kreativitas juga perlu diwujudkan dalam kegiatan pembelajaran. Penelitian ini bertujuan untuk mendeskripsikan implementasi latihan soal berbasis open-ended mathematics problems sebagai salah satu bentuk asesmen formatif yang mendukung pelaksanaan Kurikulum Merdeka, khususnya dalam mendukung kreativitas matematis siswa. Penelitian dilakukan di SMP Negeri 5 Malang dengan metode deskriptif kualitatif. Subjek penelitian adalah 32 siswa kelas VII tahun ajaran 2023/2024. Instrumen yang digunakan adalah latihan soal dan rubrik penilaian berbasis open-ended mathematics problems yang telah memenuhi kriteria valid, lembar observasi kegiatan, dan pedoman wawancara siswa. Pada implementasi asesmen berbasis open-ended mathematics problems yang telah valid, diperoleh data bahwa tingkat kepraktisan asesmen mencapai skor kepraktisan 3,74 yang berarti asesmen berbasis open-ended mathematics problems mudah untuk digunakan. Berdasarkan angket respons dan wawancara, penelitian lanjutan disarankan untuk mengintegrasikan asesmen berbasis open-ended mathematics problems dengan gamifikasi.
PROFIL PENGETAHUAN NUMERASI MAHASISWA CALON GURU MATEMATIKA [PROFILE OF PROSPECTIVE MATHEMATICS TEACHERS’ NUMERACY KNOWLEDGE]
Authors: Melissa Margaretha Madha , Kristanto Yosep Dwi
Published: June 2024

The 21st-century skills that students and teachers must have are literacy skills, learning skills and life skills. One of the literacy skills is mathematical literacy, also known as numeracy. This research aims to describe the numeracy knowledge profile of prospective mathematics teacher students. This type of research is quantitative descriptive research. The subjects of this research were 32 prospective mathematics teacher students at a private university in Yogyakarta. Data collection techniques in this research used questionnaires and interviews. The research results show that the majority of prospective mathematics teacher students are doubtful about their knowledge of numeracy. Furthermore, none of the students mentioned the complete meaning of numeracy skills; most only mentioned numeration as numbers and mathematical symbols, solving everyday problems, and number operations. Students are also unable to mention the content and context of numeracy questions. However, all students realize that as prospective mathematics teachers, it is important to study numeracy and implement it in the classroom. The suggestion to improve numeracy knowledge and skills are through lesson study that focuses on numeracy to introduce numeracy practices and as a model for prospective teachers, as well as using a student-centered learning approach, using real problems such as RME.

BAHASA INDONESIA ABSTRACT: Kemampuan abad ke-21 yang perlu dimiliki oleh siswa dan guru adalah kemampuan literasi, kemampuan belajar, dan kemampuan hidup. Salah satu kemampuan literasi adalah literasi matematika atau juga dikenal dengan istilah numerasi. Tujuan penelitian ini adalah untuk mendeskripsikan profil pengetahuan numerasi mahasiswa calon guru matematika. Jenis penelitian ini adalah penelitian deskriptif kuantitatif. Subjek penelitian ini adalah 32 mahasiswa calon guru matematika di salah satu universitas swasta di Yogyakarta. Teknik pengambilan data dalam penelitian ini menggunakan kuesioner dan wawancara. Hasil penelitian menunjukkan bahwa sebagian besar mahasiswa calon guru matematika ragu-ragu akan pengetahuan mereka tentang numerasi. Selain itu, tidak ada mahasiswa yang menyebutkan pengertian numerasi dengan lengkap, sebagian besar hanya menyebutkan numerasi sebagai angka dan simbol matematika, memecahkan masalah sehari-hari, dan operasi bilangan. Mahasiswa juga tidak mampu menyebutkan konten dan konteks soal numerasi. Walaupun demikian, semua mahasiswa menyadari sebagai calon guru matematika penting untuk mempelajari numerasi dan mengimplementasikannya di kelas. Hal yang bisa dilakukan untuk meningkatkan pengetahuan dan kemampuan numerasi yaitu melalui lesson study yang berfokus pada numerasi untuk mengenalkan praktik numerasi dan sebagai model bagi calon guru, serta menggunakan pendekatan pembelajaran yang berpusat pada siswa, menggunakan permasalahan nyata seperti PMR.
DETERMINANTS OF MILLENNIAL INVESTMENT DECISION-MAKING IN THE SHARIA CAPITAL MARKET: A COMPREHENSIVE REVIEW
Authors: Aeni Nurul Nur , Tubastuvi Naelati , Purwidianti Wida , Utami Restu Frida
Published: June 2024

Introduction: The study aims to examine the impact of financial literacy, overconfidence, regret aversion bias, herding, and risk tolerance on the investment decisions of the Indonesian millennial generation. 
Methods: The study used a quantitative approach with a sample of 120 respondents from the millennial generation who invested in the Islamic capital market. A statistical test was done using SPSS IBM 26.
Results: Financial literacy and overconfidence significantly influenced investment decisions. On the other hand, regret aversion bias, herding, and risk tolerance had no significant impact on investment decisions.
Conclusion and suggestion: The study concluded that financial literacy and overconfidence are the major factors that affect the investment decisions of the Indonesian millennial generation. The government (regulator) and related institutions should take a more proactive approach in providing outreach and education about the importance of financial literacy and overconfidence. The millennial generation is interested in investing in the Sharia capital market.
Kinematics of Balls and Light Versus the Theory of Special Relativity
Authors: Dambi Filip
Published: June 2024

The study of the emission, propagation, and reflection of balls in Newtonian mechanics, applying the laws of conservation of momentum and energy when the mass of the balls converges to zero, concludes that the kinematics of light are like those of massless balls. The kinematics of light explain why the speed of light is the constant c in each inertial frame in which the light source and reflective mirror are at rest, why the laws of physics have the same form in each inertial frame, and why any light experiment in an inertial frame cannot prove the motion of that inertial frame. The following law of mechanics governs the kinematics of balls and electromagnetic radiation: Each inertial frame drags at its velocity the balls and electromagnetic radiation emitted by bodies at rest in that inertial frame. The theory of special relativity misapplies the symmetry observed in phenomena to two inertial frames; therefore, it duplicates a physical phenomenon from one inertial frame, which is considered stationary, into another. There are multiple issues rooted in Lorentz's and Einstein's transformations. For example, transformations offer the speed of light at the constant c in the moving and opposite directions of the inertial frame. At the same time, it is variable in any other direction, converging to infinity. Time contraction in the moving direction of the inertial frame is different from time dilation in the opposite direction. It requires a ruler and time synchronization in each direction. There are no length contractions in Lorentz's and Einstein's transformations to support the fundamental concept of length contraction in special relativity. With these unacceptable conclusions, the theory of special relativity is self-negating.
Exploring Phenolic Compounds in Crop By-Products for Cosmetic Efficacy
Authors: Gomez-Molina Maria , Albaladejo-Marico Lorena , Yepes-Molina Lucia , Nicolas-Espinosa Juan , Navarro-León Eloy , Garcia-Ibañez Paula , Carvajal Micaela
Published: June 2024

Phenolic compounds represent a group of secondary metabolites that serve essential functions in plants. Beyond their positive impact on plant, these phenolic metabolites, often referred to as polyphenols, possess a range of biological properties that can promote skin health. Scientific research indicates that using phenolics derived from plants topically can be advantageous, but the activity and stability highly depend on storage of the source material and the extract method. These compounds have the ability to relieve symptoms and hinder the progression of different skin diseases. Because they come from natural sources and have minimal toxicity, phenolic compounds show potential in addressing the causes and effects of skin aging, skin diseases, and various types of skin damage, such as wounds and burns. Hence, this review provides an extensive information of the particular crops from which by-product phenolic compounds can be sourced, but pointing the need investigation according to a proper storage plant material and the choice of the best extracting method, along with an examination of their specific functions and the mechanisms by which they act to protect skin.
Regional Variability in Survival for Patients Diagnosed with Selected Central Nervous System Tumours in Canada
Authors: Wu Yifan , Walker Emily V. , Yuan Yan
Published: June 2024

Health care in Canada is managed by provinces/territories. We investigated regional differences in survival among Canadians diagnosed with central nervous system (CNS) tumours. We identified 50,670 patients diagnosed with a first-ever primary CNS tumour between 2008 and 2017 with follow-up until December 31, 2017. We selected the four highest incidence histologies and used proportional hazards regression to estimate hazard ratios (HRs) for five regions (British Columbia, Prairie provinces, Ontario, Atlantic provinces and the Territories), adjusting for sex, tumour behaviour and patient age. Ontario had the best survival profile for all histologies investigated. The Atlantic provinces had the highest HR for glioblastoma (HR=1.26, 95% CI:1.18-1.35) and malignant glioma not otherwise specified (NOS) (Overall: HR=1.87, 95% CI:1.43-2.43; Pediatric population: HR=2.86, 95% CI:1.28-6.39). For meningioma, the Territories had the highest HR (HR=2.44, 95% CI:1.09-5.45) followed by the Prairie provinces (HR=1.52, 95% CI:1.38-1.67). For malignant unclassified tumours, the highest HRs were in British Columbia (HR=1.45, 95% CI:1.22-1.71) and the Atlantic provinces (HR=1.40, 95% CI:1.13-1.74). There are regional differences in the survival of CNS patients at the population level for all four specific histological types of CNS tumours investigated. Factors contributing to these observed regional survival differences are unknown and warrant further investigation.
Protein Bioengineering of a Crucial Biopharmaceutical for Acute Lymphoblastic Leukaemia: Improving Toxicogical, Immune and Inflammatory Responses to Asparaginase
Authors: Lara Grace Verónica Ruiz , Costa-Silva Tales Alexandre , Cachumba Jorge Javier Muso , Cevallos-Espinel Johanna , Fontes Marina Gabriel , Garcia-Maya Mitla , Rahman Khondaker Miraz , RANGEL-YAGUI CARLOTA OLIVEIRA , Monteiro Gisele
Published: June 2024

Acute lymphoblastic leukaemia is currently treated with bacterial L-Asparaginase; however, its side effects bring up the special need for improved and efficient novel enzymes development. Previously, we obtained low anti-asparaginase antibody production and high serum enzyme half-life in mice with the P40S/S206C mutant; however, its specific activity was significantly reduced. Thus, our aim was to test single mutants, S206C and P40S, for in vitro and in vivo assays. Our results showed that the drop in specific activity was caused by P40S substitution. Besides, our single mutants were highly stable in biological environment simulation, unlike double mutant P40S/S206C. The in vitro cell viability assay demonstrated that mutant enzymes have higher cytotoxic effect than WT on T-cells derived ALL and on some solid cancer cell lines. The in vivo assays were performed in mice to identify toxicological effects, to evoke immunological response and to study the enzymes pharmacokinetics. From these tests, none of the enzymes was toxic; however, S206C evoked lower physiological changes and immune responses. In relation to pharmacokinetic profile, S206C has two-fold higher activity than WT and P40S two hours after injection. In conclusion, we present bioengineered E. coli asparaginases with high specific enzyme activity and lesser side effects.
Robust photocatalytic MICROSCAFS® with interconnected macropores for sustainable solar-driven water purification
Authors: Vale Mário , Barrocas Beatriz T. , Serôdio Rita , Oliveira M. Conceição , Lopes José M. , Marques Ana C.
Published: June 2024

Advanced oxidation processes, including photocatalysis, have been proven effective at organic dye degradation. Tailored porous materials with regulated pore size, shape and morphology offer a sustainable solution to the water pollution problem, by acting as support materials to grafted photocatalytic nanoparticles (NPs). This research investigates the influence of pore and particle sizes of photocatalytic MICROSCAFS®, on the degradation of methyl orange (MO) in aqueous solution (10 mg/L). Photocatalytic MICROSCAFS® are made of binder-less supported P25 TiO2 NPs within MICROSCAFS®, which are silica-titania microspheres with controlled size and intercon-nected macroporosity, synthesized by an adapted sol-gel method that involves a polymeriza-tion-induced phase separation process. Photocatalytic experiments were done both in batch and flow reactors, these latter ones targeting real-life conditions. Photocatalytic degradation of 87% in 2 hours (batch) and 29% in 5 hours (flow), was achieved, using a calibrated solar light simulator (1 sun) and a photocatalyst/pollutant mass ratio of 23. This study introduces a novel flow kinetic model which provides the modeling and simulation of the photocatalytic MICROSCAFS® per-formance. A scavenger study was performed enabling in-depth mechanistic understanding. Fi-nally, the transformation products resulting from the MO photocatalytic degradation were elu-cidated by high-resolution mass spectrometry experiments and subjected to in-silico toxicity as-sessment.
Modelling of Texture Development during Metal Forming Using FE-VPSC
Authors: Kronsteiner Johannes , Theil Elias , Ott Alois Christian , Arnoldt Aurel Ramon , Papenberg Nikolaus Peter
Published: June 2024

In directional forming processes such as rolling and extrusion, the microstructure is strongly elongated in the forming direction. This results in a preferred alignment of the crystal orientations of the initially randomly oriented grains. These preferred orientations – the texture – and elongations of the grains are the cause of the material anisotropy. This anisotropy leads to phenomena such as earing, which occur during further forming processes, e.g., during deep drawing of sheet metal. Considering anisotropic properties in numerical simulations allows to investigate the effects of texture-dependent defects in forming processes and the development of possible solutions. Purely phenomenological models for modelling anisotropy work by fitting material parameters or applying measured R-values in experiments which are applied to all elements of the part and remain constant over the duration of the simulation. In contrast, methods such as the Visco-Plastic Self-Consistent (VPSC) model, which has been used in this work, provide a deeper insight into the development of the material microstructure. By experimentally measuring the initial texture and using it as an initial condition for the simulations, it is possible to predict the evolution of the microstructure and the resulting effect on the mechanical properties during forming operations. The results of the simulations with VPSC show good qualitative agreement with tests typically used for rolled stock.
Blended Learning and Flipped Classroom in Higher Engineering Education: Case Study and Students’ Perception in the Post-COVID-19 Period
Authors: Ożadowicz Andrzej
Published: June 2024

The period of the COVID-19 pandemic resulted in a rapid development of innovative education methods, in particular using e-learning and remote work tools. The effects of this development are also post-pandemic changes in formal teaching regulations, in particular in higher education, allowing classes and lectures to be carried out with Blended Learning or Flipped Classroom methods. This paper provides information about a case study of implementing ICT technologies with elements of the mentioned methods in one of the subjects at a technical university. The implemented tools and solutions in the field of e-learning and interactivity are presented, along with information regarding their perception by students during two academic years in the post-COVID-19 period. The analysis of results of these information and student evaluations indicates their generally positive approach to such innovations in the educational path, and at the same time shows significant challenges for teachers to increase the attractiveness and effectiveness of the teaching process and the development of practical, technical skills of students.
On the Screened Kratzer Potential and Its Variants
Authors: Fernández Francisco
Published: June 2024

We argue that several potentials proposed recently for the analysis of the vibrational-rotational spectra of diatomic molecules and their thermodynamic properties exhibit a flaw. One can easily show that the parameters $D_e $ and $r_e$ in those potentials are not the dissociation energy and equilibrium bond length, respectively, as the proposers believe. We show how to overcome the mistake in a simple and quite general way.
Occupational Accidents, Injuries, and Associated Factors among Migrant and Domestic Construction Workers in Saudi Arabia
Authors: Alruwaili Musaad , Carrillo Patricia , Soetanto Robby , Munir Fehmidah
Published: June 2024

The number of migrant workers in Saudi Arabia (SA) has gradually increased, particularly in the construction industry, where migrant workers make up 89% of the workforce. They continue to experience exposure to dangerous working conditions and increased risk for occupational injury and hazards due to the work they tra-ditionally perform. To address this challenge, this study explores the differences between migrant and domestic workers’ injury and occupational accident rates in SA’s construction industry. Data were analysed from 121,999 (98.7% migrant and 1.28% domestic workers) reported accidents and injuries obtained from the General Or-ganisation for Social Insurance (GOSI) between 2014 and 2019. Chi-square test was used to examine the asso-ciations of occupational accidents and injuries among migrant and domestic workers. Migrant workers suffered more falls, strikes, collisions, rubbing and abrasions (damage caused by scraping, producing wounds), bodily reactions (e.g., reaction to chemicals), and car accidents than domestic workers. The results also show that migrant workers aged 30-39 and domestic workers 20-29 experienced more severe injuries and increased seasonal mortality throughout the six-year period examined. In addition, domestic workers achieved a higher proportion of full recovery across all types of accidents except transport and car accidents. The findings emphasise the need for ongoing safety education, training, and improved safety measures to protect the health and safety of construction workers, especially migrant workers.
Effect of Different Doses of Capsaicin Administration and Titanium Implant Osseointegration
Authors: Bingul Muhammet Bahattin , Gul Mehmet , Dundar Serkan , Sokmen Kevser , Artas Gokhan , Polat Mehmet Emrah
Published: June 2024

Background and Objectives: This study aimed to evaluate the histological and biochemical ef-fects of capsaicin on implant osseointegration and oxidative stress. Materials and Methods: Male Wistar albino rats weighing between 250 and 300 grams were used in this study. Twenty-four rats were randomly divided into three equal groups: implant + control (n= 8), implant + capsai-cin-1 (n= 8), and implant + capsaicin-2 (n= 8). 2.5 mm diameter and 4 mm length titanium im-plants were surgically integrated into the corticocancellous bone parts of the femurs. In the treatment groups, rats were injected intraperitoneally with 25 mg/kg (implant + capsaicin-1) and 50 mg/kg (implant + capsaicin-2) of capsaicin. No additional applications were made in the con-trol group. Three rats in totally were died during and after the experiment, as a result of the an-alyzes performed on 21 animals. Results: The highest total antioxidant status value was found in capsaicin dose 2, according to the analysis. The control group had the highest total oxidant status and oxidative stress index values, while group 2 of capsaicin had the lowest. After analysis, we found that there was no observed positive effect on osteointegration in this study (p> 0.05), alt-hough the bone implant connection was higher in the groups treated with capsaicin. Conclusi-ons: A positive effect on osteointegration was not observed in this study. This may be due to os-teaclast activation. However it was found that it has a positive effect on oxidative stress. Osteo-clast activation may be the cause of this phenomenon. Capsaicin was found to have a positive effect on oxidative stress (p
Translation and psychometric evaluation of the Greek version of the Attitudes Toward Transgendered Individuals Scale
Authors: Lekka Dimitra , Argyro Pachi , Togas Constantinos , Tselebis Athanasios , Toliadis Ilias , Alexias George
Published: June 2024

Numerous investigations have consistently underscored the impact of societal stigma on the well-being of transgender individuals, encompassing both those experiencing gender dysphoria (transgender) and those who have undergone gender-affirming interventions (transsexual). The primary objective of the current research is to translate and adapt the Attitudes Toward Transgendered Individuals Scale into the Greek language. This scale specifically assesses stigma, excluding components such as discreteness and violence, and is tailored to evaluate individuals within the general populace. Employing confirmatory factor analysis (CFA) and assessing gender metric equivalence, the analyses yielded highly favourable outcomes, demonstrating excellent scale fit, reliability, and content validity, reflecting the robustness of the adapted tool for the Greek population.
Enhancing Therapeutic Approaches in Glioblastoma with Prooxidant Treatments and Synergistic Combinations: In Vitro Experience of Doxorubicin and Photodynamic Therapy
Authors: Cesca Bruno Agustín , Caverzan Matías Daniel , Lamberti María Julia , Ibarra Luis Exequiel
Published: June 2024

Glioblastoma (GBM) is an aggressive brain cancer characterized by significant molecular and cellular heterogeneity, complicating treatment efforts. Current standard therapies, including surgical resection, radiation, and temozolomide (TMZ) chemotherapy, often fail to achieve long-term remission due to tumor recurrence and resistance. A pro-oxidant environment is in-volved in glioma progression, with oxidative stress contributing to the genetic instability that leads to gliomagenesis. However, the generation of reactive oxygen species (ROS) results in the dysregulation of antioxidant defenses in GBM cells, creating a vulnerability that can be thera-peutically exploited. Evaluating pro-oxidant therapies in brain tumors is crucial due to their po-tential to selectively target and eradicate cancer cells by exploiting the elevated oxidative stress levels inherent in these malignant cells, thereby offering a novel and effective strategy for overcoming resistance to conventional therapies. This study investigates the therapeutic potential of doxorubicin (DOX) and photodynamic therapy (PDT) with Me-ALA, focusing on their effects on redox homeostasis. Basal ROS levels and antioxidant gene expression (NFE2L2, CAT, GSR) were quantitatively assessed across GBM cell lines, revealing significant variability probably linked to genetic differences. DOX and PDT treatments, both individually and in combination, were ana-lyzed for their efficacy in inducing oxidative stress and cytotoxicity. An in silico analysis further explored the relationship between gene mutations and oxidative stress in GBM patients, providing insights into the molecular mechanisms underlying treatment responses. Our findings suggest that pro-oxidant therapies, such as DOX and PDT in combination, could selectively target GBM cells, highlighting a promising avenue for improving therapeutic outcomes in GBM.
Harnessing Biopolymer Gels for Theranostic Applications: Imaging Agent Integration and Real-Time Monitoring of Drug Delivery
Authors: Jirvankar Pranita S , Agrawal Surendra S , Chambhare Nikhita , Agrawal Rishabh
Published: June 2024

Biopolymer gels have gained tremendous potential for therapeutic applications due to their biocompatibility, biodegradability, and ability to adsorb and bind biological fluids, making them attractive for drug delivery and therapy. The versatility of biopolymer gels in theranostic backgrounds, with a focus on integrating imaging features and facilitating real-time monitoring of drug delivery. Different methods of delivery are explored imaging agents into biopolymer gels, including encapsulation, surface functionalization, nanoparticle encapsulation and layer-by-layer assembly techniques. Integration of Agents and Real-Time Monitoring Drug Delivery We summarize the synthesis methods, general properties, and mechanisms of biopolymer gels functionality, demonstrating their broad applications as multimodal systems for imaging-based therapeutics. These techniques not only enable multiple imaging but also provide signal enhancement and imaging a targeted facilitates, increasing the diagnostic accuracy and therapeutic efficacy. In addition, current techniques for incorporating imaging agents into biopolymer gels are discussed, and their role in precise drug delivery and monitoring.
Antibiotic Resistance in Acetic Acid Bacteria Originating from Vinegar
Authors: Kim Sun Hee , Jang Hyun Wook , Park Jin Ju , Nam Dong-Geon , Lee Su Jeong , Yeo Soo-Hwan , Kim So-Young
Published: June 2024

Acetic acid bacteria (AAB) are major contributors to the production of fermented vinegar, offering various cultural, culinary, and health benefits. Although the residual unpasteurized AAB after vinegar production are not pathogens, these are necessary the safety evaluations including antibiotic resistance for the use as starters. In this research, we investigated the antibiotics resistance profiles of 26 AAB strains, including various species of Komagataeibacter and Acetobacter, against ten different antibiotics using the E-test method. All strains exhibited resistance to aztreonam and clindamycin. Komagataeibacter species demonstrated a 50% resistance rate to ciprofloxacin, analogous to Acetobacter species, but showed twice the resistance rates to chloramphenicol and erythromycin. Genomic analysis of K. saccharivorans CV1 identified intrinsic resistance mechanisms, such as multidrug efflux pumps, thereby enhancing our understanding of antibiotic resistance in acetic acid-producing bacteria. These findings enhance understanding of antibiotic resistance in AAB for food safety and new antimicrobial strategies, suggesting the need for standardized testing methods and molecular genetic study.
Microstructure and Mechanical Properties of Laser Direct Energy Deposited Martensitic Stainless Steel 410
Authors: KANG Hyun-KI , Lee Hyungsoo , Oh Chang-Seok , Yoon Jongcheon
Published: June 2024

The aim of this work is to study the phase transformations, microstructures and mechanical properties of the martensitic stainless steel (MSS) 410 deposits produced by laser powder-directed energy deposition (LP-DED) additive manufacturing. The LP-DED MSS 410 deposits underwent the post heat treatment in austenitizing at 980℃ for 3hrs and followed by different tempering treatment at the temperatures of 250, 600, and 750℃ for 5hrs, respectively. The analyses of phase transformations and microstructural evolutions of LP-DED MSS 410 were carried out using X-ray diffraction, SEM-EDS, and EBSD. Vickers hardness and tensile strength properties were also measured to analyze the effects of the different tempering heat treatments. It reveals that as-built MSS 410 has very fine lath martensite and high hardness of about 480HV1.0 and tensile strength of about 1280 MPa, but elongation was very lower than the post heat treated ones. Precipitations of chromium carbide (Cr23C6) were most commonly observed at the grain boundaries and the entire matrix at the tempering temperatures of 600℃ and 750℃. In general, the tensile strengths de-creased from 1381MPa to 688MPa as tempering temperatures increased up to 750℃ from 250℃. Additionally, as the tempering temperature increased, the chromium carbide and tempered mar-tensite structures became coarser.
Practitioner and Public Sector Disenfranchisement in Innovative Urban Farming in Sub-Saharan Africa: Insights from Nigeria
Authors: Benjamin Emmanuel , Adegoke Abiola , Buchenrieder Gertrud
Published: June 2024

Innovative urban farming plays a vital role in enhancing food security, nutrition, livelihood resilience, and environmental sustainability in Sub-Saharan African cities. Despite this, agricultural policy and extension services have largely ignored urban contexts. Recently, national and international initiatives have started addressing this oversight by promoting circular innovations in urban food systems. To boost productivity, it is crucial to understand the challenges, opportunities, and prospects associated with innovative urban farming. Therefore, exploratory qualitative research, specifically focus group discussions, was conducted in Alimosho Local Government Area of Lagos, Nigeria, to gather the perspectives of various stakeholders. The analysis, using mind maps and a consensus index, compared views from private urban farming practitioners and local public sector representatives. Urban farmers see significant potential in innovative technologies such as hydroponics, aquaponics, recirculating aquaculture systems (RAS), drip irrigation, sack farming, and waste upcycling to improve productivity. However, they express frustration over the lack of public sector support for embracing these circular innovations. Conversely, public sector representatives cite urban farmers' behavioral and educational shortcomings, particularly their lack of internal coordination and commitment to adopting innovations. These discrepancies underscore the complex interactions between urban farmers and local public agricultural policymakers and extension agents. The study highlights the need for fundamental changes in both public and private sectors to address the challenges in urban farming innovations. Establishing local-level dialogues, as demonstrated in this study, can provide valuable insights for developing urban farming and policy in Sub-Saharan Africa.
Evaluating of Noise Reduction Techniques for Turboengine Test Stands: A Preliminary Analysis
Authors: Cristea Laurentiu , Deaconu Marius
Published: June 2024

Emphasizing the importance of acoustic attenuation in maintaining compliance with stringent noise regulations and enhancing workplace safety, the analysis covers the theoretical and practical aspects of sound attenuation in a turboengine testing stand. This paper presents a preliminary analysis and also an evaluation of a procedure for projecting a noise attenuator for industrial application and especially for turboengine test stands. While primarily focusing on the static acoustic behavior of the attenuator, considerations were also made regarding flow dynamics, Mach number-dependent attenuation, pressure drop, and self-generated noise aspects to provide a comprehensive perspective in selecting the optimal design configuration. The study investigates different calculation methods for assessment of the noise reduction for linear and staggered baffles, applied on a scaled reduced model of attenuator. Thus, the critical parameters and projecting requirements necessary for effective noise reduction in high-performance turboengine testing environments will be evaluated in a down-scaled model. Key factors examined include the selection of design parameters and configurations from various options. Advanced computational methods, like analytic and finite element analysis (FEM) are utilized to predict the acoustic performance and identify potential design optimizations. Experimental validation is performed to corroborate the simulation results, ensuring the reliability and efficiency of the attenuator. The findings indicate that a well-designed sound attenuator module can significantly reduce noise levels without compromising the operational performance of the turboengine inside a test cell.
Selective Cytotoxicity of Curcumin in Colon Cancer via Talin-Mediated Integrin β1 Activation
Authors: Oh Bo Young , Kim Hyeon Kyeong , Lee Ryung-Ah , Hong Kyung Sook , Noh Gyoung Tae
Published: June 2024

Curcumin has attracted attention for its nontoxic chemopreventive effects; however, the specific pathways underlying its anticancer effects in colon cancer remain unclear. This study investigated the potential interplay between curcumin and integrin β1 in colon cancer. HCT116 and fibroblast cells were treated with curcumin, and cell proliferation was assessed using MTT assay and western blotting. We analyzed integrin β1 expression after curcumin treatment of HCT116 cells using western blotting and confocal microscopy. The roles of talin and rab25 in integrin β1 activation by curcumin were investigated using the same methods. Curcumin treatment significantly decreased the survival of HCT 116 cells but did not significantly affect the survival of fibroblast cells. Moreover, curcumin significantly increased integrin β1 expression in HCT 116 cells, which was primarily mediated by talin. In contrast, rab25 expression remained unchanged after curcumin treatment. Using rab25-specific siRNA knockdown experiments, we confirmed that curcumin increased integrin β1 expression even in the absence of rab25. Confocal microscopy revealed a dose-dependent increase in integrin β1 and talin expression, with consistent spatial distribution patterns in response to curcumin. This study highlights the clinical significance of curcumin as a selective anticancer agent in colon cancer by modulating integrin β1 expression through a talin-mediated pathway rather than through rab25.
Testing and Visualization of Associations in Three-Way Contingency Tables: A Study on Gender Gap in Patients with Type I Diabetes and Cardiovascular Complications
Authors: Lombardo Rosaria , Beh Eric J. , Prattichizzo Francesco , Lucisano Giuseppe , Nicolucci Antonio , Eliasson Björn , Carlsen Hanne Krage , Grotta Rosalba La , Pellegrini Valeria , Ceriello Antonio
Published: June 2024

Using data from the Swedish National Diabetes Register, this study examines the gender disparity among patients with type I diabetes who have experienced a specific cardiovascular complication, while exploring the association between weight variability, age group, and gender. Fourteen cardiovascular complications have been considered. This analysis is conducted by using three-way correspondence analysis (CA) which allows for the partitioning and decomposition of Pearson’s three-way chi-squared statistic. The dataset comprises of information organized in a data cube, detailing how weight variability among these patients correlates with a cardiovascular complication, age group and gender. The three-way CA method presented in this paper allows for one to assess the statistical significance of the association between these variables and to visualize this association, highlighting the gender gap among these patients. It is worth noting that the association between weight variability, age group, and gender varies among different types of cardiovascular complications.