bluuebunny/crossref_metadata_2025 huggingface dataset:
Limb Salvage using Maggot Debridement Therapy on a Diabetic Foot Ulcer Complicated by Gas Gangrene
Authors: Yusuf Mustapha Ahmed , Muhammad Shamsuddeen , Bello Usman Muhammad , Ibrahim Mohammed Bashir
Published: April 2023

Maggot debridement therapy (MDT) has resurfaced three decades ago as a result of the steep rise in the emergence of antibiotic resistant strains of pathogenic bacteria and the need for an effective non-surgical method for wound debridement in the critically ill patients. This case study reports on the successful use of MDT to salvage the limb of the index patient who was booked for above knee amputation. The patient is a 53-year-old lady who presented with left foot ulcer of six weeks' duration to our facility. Sterile first instar larvae of L. sericata obtained from an indigenous company (Biosurg wound care Nigeria Limited) were applied using the confinement (free-ranged) method. Staphylococcus epidermidis and Pseudomonas fluorescens were isolated before the application of MDT. However, after the application, the wounds m/c/s yielded no growth. Rapid epithelization and increased vascularity of the tissues were observed in the patient after the application. Maggot debridement therapy was successfully used in the debridement of diabetic foot ulcer complicated by gas gangrene in Nigeria for the first time and the clinical outcome is encouraging.
Multiple pterygoid approach
Authors: Gaur Vivek , Doshi Anita Gala , Palka Lukasz R.
Published: April 2023

The intended target site to engage a fixture distal into the tuberosity is the pterygoid apophysis that comprises the maxillary tuberosity, pyramidal process of the palatine bone, and the pterygoid process of the sphenoid bone. Pterygoid implants are incorrectly labeled in literature owing to the fact that they are actually root form conventional implants and should hence be termed as 'tubero-pterygoid implant'. An implant engaging the pterygoid apophysis/pillar taking distal maxillary support and avoiding successfully the cantilever situation is called a pterygoid implant. It essentially does not acquire primary with support of distal maxilla initially from the tuberosity. Instead, it makes its way into the apophysis and sometimes via a transsinus approach. A tubero-pterygoid implant, because of the root form screw shape fixture that is wide at the crestal aspect and converging toward the apex, takes the primary support from the tuberosity and engages the pterygoid pillar apically, thus allowing more bone to implant contact but has its limitation in deficient/atrophied tuberosity.
Modified Cupar's method for immediate diastema closure
Authors: Deshpande Ashutosh Avinash , Muthusekhar M. R. , Hemavathy O. R. , Murali Swetha
Published: April 2023

Anterior maxillary osteotomy or ostectomy (AMO) is a safe, reliable, and easily adaptable procedure routinely performed in orthognathic surgery for the management of the dentoalveolar segment of the anterior maxilla. The anterior segmental maxillary osteotomy was first performed in 1921 by Cohn–Stock. Several modifications were done regarding approaches for AMO; however, Cupar's method is the most preferred approach by the surgeons and in practice since several decades. A novel midline split osteotomy is performed in combination with Cupar's method for superior and posterior repositioning of anterior maxillary segment in combination with immediate closure of diastema in this case report.
Single-stage reconstruction of traumatic lower lip defects with chin island myocutaneous and labial mucosal flap
Authors: Sahai Rahul , Singh Sudhir
Published: April 2023

In the present study of eight cases of traumatic lower lip defects, the reconstruction was achieved in a single stage by V-Y advancement island chin myocutaneous flap and labial mucosal advancement flap. There are many methods described for the reconstruction of small-to-large size of lower lip defects from straight-line closure of small defects to local flaps and free flaps for large defects. V-Y advanced chin flap has been reported previously also for the repair of lower lip defect with varying results. The vermilion reconstruction in others reported cases was done with the free mucosal grafts, V-Y labial mucosa advancement, or pedicled tongue flaps. Tongue flap is a two-stage procedure with esthetically unnatural look and an irregular surface of the vermilion. The free mucosa graft showed necrosis partial or complete resulting in irregular surface of vermilion and notching in the lip. V-Y labial mucosa advancement was done more for a small defect of the lip only. In the present series, we have repaired the vermilion of the lip by labial mucosal advancement flap, muscle by advancement of orbicularis oris from chin flap, and skin by V-Y advancement of island myocutaneous chin flap. Our results showed normal oral size with no evidence of microstoma or commissural distortion; oral competence was good with normal sphincteric function. The vermilion reconstructed had normal color and sensation. Lip seal was very good without notching defect in the vermilion. Drooling of saliva or speech defect was not noticed. The facial expressions and the look of the face were near normal. Hence, esthetically and functionally, the results were good without any irregularity or notching of the lip along with no incidence of drooling of saliva. We think that this technique may be considered as a procedure of choice for managing the moderate-to-large post traumatic defects of the lower lip. It is good esthetically and functionally besides being single stage for reconstructing moderate-to-large defects of the lower lip and is satisfying to the patient.
Guided autotransplantation of tooth
Authors: Srivastava Sanjeev , Gupta Khushboo , Dubey Sandeep , Singh Arohan
Published: April 2023

This case report describes a novel approach of guided autotransplantation of tooth so that we can assess its feasibility, accuracy, and stability. In the present case, autotransplantation of a third molar at the recipient site of mandibular first molar was done. Three-dimensional (3D) replica of donor tooth along with surgical guiding template was virtually designed and fabricated using 3D printing. The 3D replica and surgical template helped in the surgical modification of recipient site and placement of donor tooth in the exact position. Root canal treatment of the donor tooth was carried out after 2 weeks. At 6 months' follow-up, the transplanted tooth was functional with no evidence of mobility or periodontal inflammation. Radiographic evaluation showed the absence of widening of periodontal space and external root resorption. Hence, the transplantation of the third molar is an outstanding procedure for replacing a lost permanent molar tooth which in turn restores esthetics and function.
Evaluation of effects of platelet-rich fibrin on treatment outcomes after impacted mandibular third molar surgery
Authors: Shruthi T. M. , Shetty Akshay D. , Akash K. S. , Ahmed Fazeel , Shetty Navya , Singarapu Ravalika
Published: April 2023

Background and Objective:

Impaction of the third molar teeth is a common disorder which often necessitates their removal. After third molar surgery, the common postoperative sequelae are pain, trismus, and buccal swelling. Our study sought to evaluate the effect of platelet-rich fibrin (PRF) on postoperative pain, swelling, trismus after surgical extraction of impacted mandibular 3rd molars.

Materials and Methods:

Over a period of 22 months (December 1, 2016–September 30, 2018), 44 patients in the age group of 18–40 years, who required surgical extraction of impacted third molar and met the inclusion criteria were recruited. After surgical extraction of the third molar, only primary closure was performed in the control group (22 Group), whereas PRF was placed in the socket followed by primary closure in the study group (22 patients). The outcome variables were pain, swelling, and maximum mouth opening were measured with a follow-up period of 1 week.

Results:

The application of PRF in the study group lessens the severity of immediate postoperative sequelae such as pain, swelling, and trismus compared to the control group.

Conclusion:

The treatment outcomes and postoperative sequel were better in the PRF group as compared to other control group on days 1, 3, and 7 postoperatively.
Costochondral grafts for reconstruction of acquired mandibular defects involving the temporomandibular joint
Authors: Kar Indu Bhusan , Sarkar Dibya Falgoon , Samal Dipti , Mishra Niranjan
Published: April 2023

Autogenous reconstruction of temporomandibular joint (TMJ) with costochondral graft (CCG) has been a popular method of growth center transfer in children. However, unpredictable growth pattern of CCG has been reported in children that often leads to dentofacial deformities in future. This institutional study describes the results of mandibular reconstruction with CCG in two growing children, one with plexiform ameloblastoma of mandible and the other with unilateral TMJ ankylosis. Long-term follow-ups showed a significant growth of the grafts in both the patients. However, there was a lack of uniformity in the amount and rate of growth. The authors support the theory that CCG possesses innate growth potential and is a desirable option for reconstruction of acquired mandibular defects involving the TMJ in pediatric population. However, regular postoperative monitoring is necessary for such patients as the graft shows an unpredictable growth pattern.
Nasal sebaceous carcinoma
Authors: Tavanafar Saeid , Gheibollahi Hamed , Mousavi Seyede Sona , Dehghanian Amirreza
Published: April 2023

Nasal sebaceous carcinoma is an extremely rare cutaneous malignancy. We present the case of an 86-year-old female who had a skin nodule with surface telangiectasia on the right ala of the nose. The lesion had been removed and has been reconstructed with an advancement rotational flap with a minimal residual defect. Upon histopathological examination, the lesion was diagnosed with sebaceous carcinoma. The patient was followed up because of the high rate of recurrence as well as metastatic potential. No recurrence occurred during 4 years of follow-up, and the patient was unwilling to reconstruct the remaining alar defect. We present a rare skin cancer case that could be encountered during the head and neck examination by oral and maxillofacial surgeons. By reporting this case, we aimed to raise the awareness and familiarize clinicians with these less common lesions.
Efficacy of tranexamic acid in prevention of alveolar osteitis following surgical removal of impacted mandibular third molar
Authors: Jadhav Ajinath Nanasaheb , Shushma G. , Deshmukh Vijay Dnyandev
Published: April 2023

Context:

Many preventive measures are described to avoid alveolar osteitis (AO) during third molar surgery (TMS), but very few are found to be effective. Tranexamic acid (TA), an antifibrinolytic agent, impedes the proteolytic degradation of fibrin and prevents blood clot disintegration.

Aims:

The study was conducted to determine the efficacy of intra-alveolar application of TA soaked in Gelfoam in prevention of AO.

Settings and Design:

This was a randomized control trial.

Materials and Methods:

A total of 200 patients (100 in control group and 100 in study group) reporting for TMS were allocated randomly. Following surgery, TA soaked in gel foam was placed in socket and sutured in the study group, while in the control group, closure was done by suturing. Patients followed subsequently to observe the incidence of AO, pain severity, and duration of healing after AO.

Statistical Analysis:

Z-test, Mann–Whitney test, and t-test were applied, respectively, to compare the incidence of AO, severity of pain, and duration of healing between the two groups.

Results:

The incidence of AO in the control group was 18% and 6% in the study group. Patients in the control group experienced severe pain as compared to patients in the study group. The duration of healing varied from 12 to 16 days in the control group, but in the study group, it was <10 days.

Conclusion:

TA significantly reduces the incidence of AO in addition to the reduced severity of pain and enhanced healing. We recommend the routine use of TA, owing to its astonishing rewards.
Minimally traumatic extraction techniques in nonrestorable endodontically treated teeth
Authors: Sharma Sneha D. , Gupta Ashish , Bansal Pankaj , Alexander Mohan , Vidya B , Gupta Himani
Published: April 2023

Aim:

The goal of this study was to assess the effectiveness of piezotome as compared to periotome extractions of nonrestorable endodontic treatment of teeth in terms of operational time, pain control, and postoperative bone loss considering the prosthetic rehabilitation in future.

Materials and Methods:

A double-blind, randomized controlled trial was conducted with 100 patients who wanted single-rooted teeth to be extracted (which failed endodontically). The participants have been randomized into two equal groups named as - (i) a periotome group (ii) and a piezotome group. Duration of the surgery, postoperative pain within 7 days, complications (if any) associated with the extraction process were performed as a part of clinical assessment. Bone loss has been analyzed 6 months after the surgery radiographically. The data have been recorded and analyzed using the version 22.0 of the SPSS software package.

Results:

All parameters in the periotome category (P < 0.05) were statistically significant except for bone loss and gingival laceration in comparison to piezotome group. In the piezotome group, a longer time was observed for surgery and delayed pain control was achieved. In our study, we found statistically significant more marginal bone loss in piezotome group in comparison with periotome group.

Conclusion:

The findings of this study indicate that for intraoperative and postoperative comfort periotome could be used as a safer and cheaper option for atraumatic extractions but piezosurgery may prove as a better choice soon for surgeries in the maxillofacial region to maintain soft-tissue integrity.
Insights of dental postgraduate students and guides toward change in MDS examination pattern
Authors: Kalghatgi Shrivardhan , Khairnar Mahesh Ravindra , Dalvi Tanushri Mahendra , Dwivedi Archana , Saoji Hrishikesh , Chandra Akhilesh
Published: April 2023

Introduction:

According to the notification dated May 17, 2018, no. DE-14-MDS-2018/2131 published by the Dental Council of India, basic sciences theory examination (Paper-1) will be conducted before the commencement of II-year MDS academic year instead of III-year MDS end. Hence, this study was conducted to assess the opinions regarding this recent change in the curriculum among I MDS students, II MDS students, and their respective postgraduate (PG) guides.

Methodology:

The study was conducted on 120 participants from three dental colleges. All the participants were interviewed using a pretested, structured questionnaire. The initial part of questionnaire consisted of demographic information of the study participants followed by ten questions targeted to assess the perception toward change in MDS examination pattern. Statistical analysis was performed using SPSS software v20, and Chi-square test was used for comparison of responses among PG students and PG guides.

Results:

Questions pertaining to the need of allowed to keep term (ATKT), assumption to improved concentration on specialization subjects, and increase in understanding of the subject have received maximum positive response. Negative responses were more for the questions such as hampering of PG curriculum, effect on dissertation selection process, and rendering quality treatment to the patient. Responses to necessity of ATKT and the assumption to better concentrate on specialization subject later differed significantly among the participants.

Conclusion:

The present study results revealed an overall positive perception toward the change in MDS curriculum pattern among the study participants.
Sandwich osteotomy with interpositional grafts for vertical augmentation of the mandible
Authors: Bera Rathindra Nath , Tandon Sapna , Singh Akhilesh Kumar , Bhattacharjee Bappaditya , Pandey Sapna , Chirakkattu Tomin
Published: April 2023

Sandwich osteotomy is a technique for vertical augmentation based on the principle of a graft being placed between two pedicled native bones. The inherent vascularization helps in graft consolidation. The aim is to review the bone height gained, implant survival and pitfalls with sandwich osteotomy. The PICO model was used to identify the suitable studies for the review. Oxford level of evidence, Newcastle Ottawa Scale and Cochrane's tool for Systematic Reviews of Interventions was applied for identifying study quality. Meta-analysis was performed with the help of RevMan. Funnel plot was used to evaluate publication bias and bias during article selection. Difference in means was used as principal summary measure. Fixed effects model with inverse variance statistics was used. I2test statistics was applied to identify study heterogeneity. Forest plots were produced for the outcome variables with 95% confidence interval (CI) and overall treatment effects and subgroup effects at a significance level of 0.05. The overall implant survival rate ranged from 90%-100% and prosthetic survival rate from 87%-95%. An overall 6-10mm of bone can be gained in the anterior mandible and 4-8mm in the posterior mandible. A total of 1030 implants were placed of which 988 implants survived after the mean follow up periods (odds ratio: 0.77, 95% CI: 0.49-1.21). Implant survival is independent of the graft being used. Vertical augmentation in the posterior mandible is limited compared to anterior owing to the presence of inferior alveolar nerve and the keratinized tissue deficiency.
Efficacy of low-level laser therapy in the management of postoperative surgical sequelae after surgical removal of impacted mandibular third molars
Authors: Thorat Sagar D. , Nilesh Kumar
Published: April 2023

Introduction:

The study is aimed to evaluate the effectiveness of low-level laser therapy (LLLT) in the control of pain, swelling, and trismus after the surgical removal of impacted mandibular third molars.

Materials and Methods:

A prospective study was conducted on thirty patients requiring surgical removal of the impacted mandibular third molar. Mesioangular impacted third molar with class I level B position (according to the Pell and Gregory classification) were included in the study. The study group (n = 15) received LLLT using diode laser of wavelength 980 nm and the control group (n = 15) received routine postoperative care without LLLT. The parameters evaluated were intensity of pain, maximum mouth opening, postoperative swelling, healing at the surgical site, and presence of dry socket.

Results:

The mean score of pain, swelling, and trismus in the study group were statistically lower as compared to the control groups. Healing assessment using Laury and Turnbull healing index inferred that the healing at the seventh postoperative day was superior in the study group as compared to the control group.

Conclusions:

LLLT with a diode laser of wavelength 980 nm can effectively reduce pain, swelling, and trismus in the postoperative phase after surgical extraction of the mandibular impacted third molar and promote healing at the operative site.
An objective assessment of microneedling therapy in atrophic facial acne scars
Authors: Waghmare Komal Babu , Sequeira Joyce , Rao B. H. Sripathi
Published: April 2023

Context:

Microneedling therapy is one of the recent advances in treating acne facial scars.

Aim:

To evaluate the efficacy of microneedling therapy in the treatment of atrophic acne facial scars.

Settings and Design:

A total number of 10 patients between the age group of 20 and 40 years (8 women and 2 men) who complained of acne scars from November 2012 to August 2014 were selected for the study.

Subjects and Methods:

Microneedling therapy was performed following the application of the Eutectic Mixture of Local Anesthetics in an interval of 2 months. All patients underwent three sessions. A follow-up of 2 months after the last sitting was carried out.

Statistical Analysis:

Cochran's Q-paired test, Kendall's W-test, and Pearson's correlation were used for statistical analysis.

Results:

Patients in our study had three forms of acne scars: box-scar, icepick form, and rolling scars. Patients were told to rate the outcome of the treatment at the end of the follow-up. Three observers randomly selected were shown the pre- and postoperative photographs of the patients to rate the treatment outcome. Statistically there was no interobserver bias. Ninety percent reduction in number of scars and depth of scars was noted at the end of three sittings. The improvement in pigmentation was insignificant. Seventy percent improvement in the skin texture was noted. Nine patients suffered from transient postinflammatory erythema and six patients had postoperative swelling.

Conclusion:

Microneedling therapy is a safe and effective method of treating acne scars.
Correspondence theorems for Hopf algebroids with applications to affine groupoids
Authors: El Kaoutit Laiachi , Ghobadi Aryan , Saracco Paolo , Vercruysse Joost
Published: April 2023

We provide a correspondence between one-sided coideal subrings and one-sided ideal two-sided coideals in an arbitrary bialgebroid. We prove that, under some expected additional conditions, this correspondence becomes bijective for Hopf algebroids. As an application, we investigate normal Hopf ideals in commutative Hopf algebroids (affine groupoid schemes) in connection with the study of normal affine subgroupoids.
Clinical Spectrum and Microbial Etiology of Bone and Joint Infections in Children: A Retrospective Analysis from South India
Authors: Jaybhaye Amol , LG Shyamsunder , Dash Nabaneeta , Verghese Valsan , Chacko Anila , Madhuri Vrisha , Palocaren Thomas , Gahukamble Abhay , James Deeptiman , Prakash John , Rose Winsley
Published: April 2023

Acute infections of bone and joints are medical emergencies. Early diagnosis and treatment are essential for limb salvage and prevention of deformities. Data from developing countries are essential to develop region-specific treatment guidelines including choice of empiric antibiotics. We reviewed electronic medical records of children (≤ 12 years old) admitted to the pediatrics or orthopedics department of a tertiary care hospital in South India from 2013 to 2017 with a diagnosis of septic arthritis and/or osteomyelitis. Clinical, microbiological, and follow-up data were collected and analyzed. The median (interquartile range, IQR) age of the children (N = 207) was 48 (7.5–105) months. Acute infections were more common in infants, whereas chronic cases were common in children > 5 years of age. Staphylococcus aureus (71%) was the most common organism identified. Gram-negative organisms were more frequently isolated in infants compared with older children. Blood and/or wound culture positivity was 78% (N = 161) overall and 78% (N = 31) in chronic cases. The median (IQR) duration of antibiotics was 7 (5–8) weeks. Sequelae and readmissions occurred in 47% (N = 81) of the 172 patients followed for a year. Culture positivity rates especially of wound were high even after receiving antibiotics.
Verbal and Social Autopsy of Adult Deaths and Adult Care-Seeking Pattern in Mozambique, 2019–2020
Authors: Rahman Md Hafizur , Macicame Ivalda , Wilson Emily , Nhachungue Sheila , Amouzou Agbessi
Published: April 2023

In sub-Saharan Africa, recent data about causes of adult death and care-seeking during illnesses are limited. This analysis examines adult deaths using verbal and social autopsy data from a nationally and provincially representative sample registration system in Mozambique. Causes of death among those 18 years and older were assigned using the InSilicoVA algorithm, and underlying social causes were examined using the pathway to survival model. Care-seeking was analyzed in different groups to determine if care was sought from formal providers (doctor, nurse/midwife, and trained community health worker) or other providers (traditional provider, family member, and pharmacist), using χ2 tests and multinomial regression models. Among the 4,040 adult deaths reported during 2019–2020, the major causes were HIV (17%), cancer (13%), injury (10%), cardiovascular diseases (9%), pneumonia (7%), tuberculosis (5%), and maternal causes (3%). Formal care-seeking was more likely among adults who had primary or higher level education (relative risk ratio [RRR]: 1.6, P < 0.001; RRR: 1.7, P < 0.01), were married (RRR: 1.3, P < 0.01), and had highest household wealth (RRR: 3.1, P < 0.001). Formal care-seeking was less likely among adults who were male (RRR: 0.7, P < 0.001), had social capital (RRR: 0.7, P < 0.05), or resided in the southern region (RRR: 0.4, P < 0.001). Information about adult causes of death is useful for formulating policy and for developing, monitoring, and evaluating programs to improve adult health in Mozambique. Care-seeking–related information helps identify barriers for seeking care from formal health providers while emphasizing the need for generating local resources and strengthening outreach health systems service delivery.
Al2O3 ve SiC Takviyeli AA2024 Esaslı Kompozitlerin Mikroyapı ve Mekanik Özelliklerinin İncelenmesi
Authors: ÇALIGÜLÜ Uğur , ÇANAKÇI Aykut , TÜRKMEN Mustafa , DARCAN Nida , KAÇMIŞ Muhammet Vahittin
Published: April 2023

Al2O3 ve SiC Takviyeli AA2024 Esaslı Nanokompozitlerin Mikroyapı ve Mekanik Özelliklerinin İncelenmesi

Uğur Çalıgülü1, Aykut Çanakçı2, Mustafa Türkmen3, Nida Darcan1, Vahittin Kaçmış1

1Fırat Üniversitesi, Teknoloji Fakültesi, Metalürji ve Malzeme Mühendisliği Bölümü, Elazığ

2Karadeniz Teknik Üniversitesi, Mühendislik Fakültesi, Metalurji ve Malzeme Mühendisliği Bölümü, Trabzon

3Gebze Teknik Üniversitesi, Ulaşım Teknolojileri Enstitüsü, Gebze/Kocaeli

Özet

Bu çalışmada; üstün mekanik ve fiziksel özelliklere sahip olduğundan dolayı mühendislik, otomotiv ve savunma sanayisi gibi önemli alanlarda vazgeçilmez bir yere sahip nanokompozit malzemeler toz metalürjisi yöntemiyle üretilmiştir. Günümüzde sıklıkla kullanılan karbür parçacıkları dikkate alındığında, yüksek aşınma direncine ve yüksek ısı dayanımına sahip olmasından dolayı Silisyum Karbür (SiC) tercih edilmiştir. Diğer bir takviye malzemesi olarak ise, alüminyum alaşımı (AA2024) ile uygun ara yüzey bağlanma yeteneğine sahip olmasından dolayı Alüminyum Oksit (Al2O3) tercih edilmiştir. Numuneler farklı oranlarda AA2024/Al2O3 ve AA2024/SiC toz karışımları hazırlanarak 560 ºC sıcaklıkta, 120 dakika süreyle ve 500 MPa basınç altında sıcak presleme yöntemi ile üretilmiştir. Toz metalurjisi yöntemiyle elde edilen 63 μm partikül boyuta sahip AA2024 matrisli Al2O3 ve SiC takviyeli nanokompozitlerin mikroyapılarını ve mekanik özelliklerini incelemek amacıyla; SEM, EDS ve XRD görüntüleri ile mikrosertlik, yoğunluk, çekme, korozyon ve balistik testleri yapılmıştır. Yapılan test sonuçlarına göre; AA2024/Al2O3 ve AA2024/SiC nanokompozit malzemelerin en iyi çekme testi sonucu % 2 takviyeli nanokompozit malzemelerde tespit edilmiştir. Sertlik değerleri, artan takviye oranı ile artış göstermiştir. Al2O3 ve SiC takviye oranındaki artışın korozyon direncinin artmasına sebep olduğu ve AA2024 matrisinin mekanik özelliklerini olumlu yönde etkilediği tespit edilmiştir. Balistik test sonucunda ise en yüksek değeri % 2 takviyeli nanokompozit malzemeler vermiş olup, daha yüksek takviye oranlarında ise balistik test değerlerinde düşüşler meydana gelmiştir.

Anahtar Kelimeler: AA2024, Al2O3, SiC, Nanokompozitler, Mekanik Özellikler.
Dispersive liquid-liquid microextraction/HPLC techniques for determination of oxytetracycline and doxycycline residues in beef samples: method developments and statistical analysis
Authors: Aliu Muinat , Junaid Abibat , Ibraheem Abdulrahman , Ishaq Aisha , Lawal Abubakar , Ayeni` Kikelomo , Lawal Amudalat , Abdulra'uf Lukman
Published: April 2023

A rapid, cost-effective and environment-friendly sample pre-treatment method involving dispersive liquid-liquid microextraction (DLLME) and high-performance liquid chromatography (HPLC) was developed and applied for the extraction of oxytetracycline and doxycycline residues in beef samples (liver, kidney and muscle). Several influencing factors associated with the extraction and separation of these antibiotics residues, such as sample size, type and volume of disperser and extraction solvents, centrifugation speed and time, were optimized using Plackett-Burman design and central composite design, while insignificant factors were fixed at values determined using univariate analysis. Figures of merit of the analytical methodology including the limit of detection (LOD), the limit of quantification (LOQ), accuracy (in terms of average recoveries), precision and calibration functions were established according to the European Union commission decision 2002/657/EC. Linearity, in the range of 5–500 µg/kg, was obtained with regression coefficients ranging from 0.9983 – 0.9999. Inter-day repeatability, intra-day precision, LODs and LOQs obtained were 3.81 – 14.90%, 3.80 – 8.70%, 4.21 – 4.69 µg/kg and 14.02 – 15.65 µg/kg respectively. Samples with detectable drug residues have oxytetracycline being the most commonly detected. The developed method was successfully established and the concentration levels of drug residues detected were lower than the European Union set maximum residue level (MRL).
Characterization of Guaiacol Peroxidase Enzyme from Carambola Fruit
Authors: TAŞ Ömer , YAYLA Maviş , EKİNCİ Deniz
Published: April 2023

Carambola is a fruit grown in tropical and subtropical regions of the world. Natural antioxidants including vitamin C, carotenoids, and certain phenolic substances are abundant in carambola fruit. As antioxidants support health by acting as nutraceutical and functional food additives, they help preserve food by preventing oxidation processes. The oxidation of various organic or inorganic substrates by hydrogen peroxide or organic peroxides as terminal oxidants is a process in which peroxidase, which is abundantly present in fruits and vegetables, participates. In this study, guaiacol peroxidase enzyme from carambola fruit was partially purified and characterized. Purification procedure made up the homogenate preparation, ammonium sulfate precipitation, and dialysis. After purification, optimum ionic strength, pH and substrate concentration were investigated. These values were determined as 200 mM Tris, pH: 7.5, 7.5 mM H2O2 and 15 mM guaiacol for carambola fruit guaiacol peroxidase enzyme, respectively.
KARA MÜRVERİN BAĞIŞIKLIK SİSTEMİ ÜZERİNE ETKİSİ
Authors: ÖNEY Başak , BAŞER Zehra
Published: April 2023

Kara mürver, latince ismiyle Sambucus nigra, uzun yıllardır kullanılan Adoxaceae

familyasına ait bir bitkidir. Ortak isimleri arasında kara mürver, siyah yaşlı,

Avrupa yaşlısı, Avrupa mürveri ve Avrupa kara mürveri de vardır. Hipokrat

tarafından doğanın en şifalı bitkisi olarak görüldüğü de bilinmektedir. Meyveleri

koyu mor-siyah renktedir. 100 gramı ortalama 73 kalori içerir ve vitamin-mineral

açısından oldukça zengin bir yapıya sahiptir. Kara mürver, yapısında birçok faydalı

bileşik bulundurmaktadır. Bunlar arasında en önemli olanlar flavonoidler, fenolik

asitler ve antosiyaninlerdir. En baskın olanı ise antioksidan özelliği olduğu bilinen

antosiyaninlerdir. Bunların yanında kara mürver, içerdiği siyanojenik glikozitlerden

kaynaklı olarak zehirlenmeye sebep olabilmektedir. Bunu önleyebilmek için

mutlaka ısıl işleme maruz bırakıldıktan sonra tüketilmesi gerekmektedir. Kara

mürverin diüretik, laksatif, diyaforetik, antioksidan, antiviral, immünomodülatör,

antiinflamatuar, antimikrobiyal, antikonvülsan, antidepresan ve antikarsinojenik

gibi çeşitli etkilere sahip olduğu bilinmektedir. Aynı zamanda diyabet, hipertansiyon,

obezite, hiperlipidemi, metabolik işlev bozuklukları, üriner parametreler

üzerinde de kullanılabilmektedir. Hem sağlıklı hem de hasta organizmalarda vücudun

savunma mekanizmalarını düzenlemeye destek olarak bağışıklık sistemini

güçlendirdiği bilinmektedir. Henüz çalışmalar yetersiz olsa da COVID-19 için de

kullanılabileceği düşünülmektedir. Bu derlemede kara mürverin antioksidan, antiviral,

antibakteriyel, antiinflamatuar, antikanser etkileri ve bağışıklık sistemiyle

ilişkisinden bahsedilmiştir.
The Decision of Terminating Pregnancy: The Male and Female Perspective
Authors: KAYA ŞENOL Derya , AYDIN ÖZKAN Semiha , ÇİÇEKOĞLU ÖZTÜRK Pınar , HOTUN ŞAHİN Nevin
Published: April 2023

Aim: The aim of this study was to investigate the male and female perspectives

in the decision of terminating pregnancy.

Method: This descriptive study was conducted between January 2017 and May

2017. The sample, consisted of a total of 190 individuals including 100 married

women and 90 married men. The data were collected using a questionnaire including

questions about the views of women and men concerning the decision of

terminating pregnancy.

Results: 85% of the women and 63.3% of the men who participated in the study

stated that it was up to a woman to make the decision of terminating pregnancy

(p
Hemşirelik Öğrencilerinin Kardiyovasküler Hastalıklar Risk Faktörleri Bilgi Düzeylerinin Belirlenmesi
Authors: YARDIMCI GÜREL Tuğba
Published: April 2023

Amaç: Bu araştırmanın amacı bir devlet üniversitesinde öğrenim görmekte

olan hemşirelik öğrencilerinin kardiyovasküler hastalıklar risk faktörleri bilgi düzeyleri

ve ilişkili faktörlerin belirlenmesidir.

Yöntem: Tanımlayıcı nitelikte olan bu araştırma, hemşirelik bölümünde öğrenim

gören ve araştırmaya katılmayı kabul eden toplam 275 öğrenci ile yapılmıştır.

Araştırma verileri Şubat-Mart 2020 tarihleri arasında, yüz yüze görüşme yöntemiyle,

“Sosyodemografik Özellikler Formu” ve “Kardiyovasküler Hastalıklar Risk

Faktörleri Bilgi Düzeyi (KARRİF-BD) Ölçeği” kullanılarak toplanmıştır. Verilerin

değerlendirilmesinde tanımlayıcı istatistikler (frekans, ortalama, standart sapma),

Student t-testi, One-Way ANOVA ve Kruskal Wallis testleri kullanılmıştır.

Bulgular: Araştırmaya katılan öğrencilerin yaş ortalaması 20.51±2.53, %69.5’i

kadın, %32.4’ü birinci sınıftır. Öğrencilerin ölçek puan ortalamaları 20.93±4.31’dir.

Yapılan analizler sonucunda üçüncü sınıfta olma, kadın cinsiyet, sağlık meslek lisesi

mezunu olma, tuzsuz beslenme ve sigara kullanmama durumlarının kardiyovasküler

hastalıklar risk faktörleri bilgi düzeylerinde istatistiksel olarak anlamlı

farklılığa sebep olduğu saptanmıştır (p
Relationship Between Mothers’ Anxiety Levels and Discharge Readiness in the Early Postpartum Period After Vaginal Delivery
Authors: AKSU Aslihan , BULDUM Aysu , DEĞİRMENCİ Filiz , VEFİKULUÇAY YILMAZ Duygu
Published: April 2023

Aim: The present study aimed to determine whether there was a relationship
between anxiety and discharge readiness during early postpartum period in women
who had given birth via vaginal delivery.
Method: The sample of study consisted of 93 mothers hospitalized in our postpartum
ward after vaginal delivery. Research data were collected using “Personal
Information Form”, “State scale of the State-Trait Anxiety Inventory(STAI)” and
“Readiness for Hospital Discharge Scale–New Mother Form(RHD-NMF)”. Descriptive
statistics, Student’s t-test, one-way analysis of variance (ANOVA), Tukey’s
test and Pearson’s correlation coefficients were used in evaluation of the data.
Results: The mean age of the mothers included in the study was 25.37±5.40
years. The mean STAI and RHD-NMF scores of the mothers were 35.15±9.59 and
145.64±32.35, respectively. It was determined that 11.8% of mothers were not ready
for discharge and 39.8% had anxiety. A statistically significant moderate negative
correlation was found between STAI and RHD-NMF scores (r=-0,445; p
Hemşire ve Ebelerin Kadınlara Pelvik Kas Egzersizi Öğretimine Yönelik Uygulamaları
Authors: KARADENİZ BENLİ Cansu , DOĞAN ÖZDEMİR Nedime Gül , KULAKAÇ Özen
Published: April 2023

Amaç: Çalışma, kadın doğum kliniklerinde çalışmakta olan ebe ve hemşirelerin

Pelvik Kas Egzersizi (PKE)’ni bir girişim olarak Hemşirelik Girişimleri Sınıflaması

(Nursing Intervention Classification-NIC)’na göre öğretme ve uygulatma

durumunu belirlemeyi amaçlamaktadır.

Yöntem: Araştırma tanımlayıcı olarak yapılmıştır. Çalışmanın evrenini, Karadeniz

bölgesinde yer alan bir ilin devlet ve üniversite hastanelerinin kadın doğum

kliniklerinde çalışmakta olan 73 hemşire ve ebe oluşturmuştur. Çalışmada örneklem

seçimine gidilmemiş, evrenin tamamı çalışmaya alınmıştır. Araştırmada veriler

Kişisel Bilgi Formu ve NIC’in Pelvik Kas Egzersizi Aktiviteleri Formu kullanılarak

toplanmıştır. Araştırmada veriler sayı ve yüzde olarak ifade edilmiştir.

Bulgular: NIC’in PKE Aktiviteleri Formuna göre hemşire ve ebelerin kadınlara

PKE girişimlerini uygulanma oranları %4.1-72.6 arasında değişmektedir. Formda

yer alan “Boşaltım baskısını fark edebilme durumunu belirleme hakkında bireyi

bilgilendiririm.” girişimi belirtilen en yüksek (%80.8) ve “Kadınları, bir parmaklarını

vajinaya koyarak ve sıkarak, Levator ani ve ürogenital kaslarını fark edebilecekleri

konusunda bilgilendiririm.” ise belirtilen en düşük (%27.4) uygulanma

oranına sahiptir.

Sonuçlar ve Öneriler: Araştırmanın önemli bir sonucu olarak hemşire ve ebelerin

PKE’nin girişim basamaklarını kadınlara uygulama oranları iki madde dışında

oldukça düşüktür. PKE girişimlerinin NIC’e göre uygulanması, uluslararası

uygulama standartlarına ulaşılmasına ve bu alanda ortak bir dil oluşturulmasına

katkı sağlayacaktır. Aynı zamanda bu girişimlerin kullanılması kadın sağlığının

geliştirilmesine ve kadınların yaşam kalitesinin artırılmasına yardımcı olacaktır.
Current State of Permafrost Landscapes of the Prilensky Plateau
Authors: Fedorov Nikolai A. , Shestakova Aliona A.
Published: April 2023

The article presents the results of studying the structure of permafrost landscapes in the area of discontinuous distribution of permafrost soils in large-scale mapping. The actual material was collected by the authors in the course of research and field work on the Power of Siberia project. Maps of terrain types, types of vegetation and a permafrost-landscape map of the key area "Mezhalasie" were compiled. Natural territorial complexes in the area of survey were systematized. The features of the permafrost landscapes distribution were studied, their differentiation was carried out, and the area of icy soils distribution was calculated.
Principals’ Integration of ICT in Curriculum Implementation for Sustainable Development
Authors:   Department of Educational Management & Policy, Nnamdi Azikiwe University, Awka, Nigeria, Nneka Okafor, Judith
Published: April 2023

The integration of ICT in secondary school curriculum has been widely advocated as much needed in the 21st century skills to improve the standard of education. However, this can be promoted through acquiring ICT skills in several ways such as software development, programming, networking, web design, cloud computing, Augmented Virtual Reality (AVR), Internet-of- Things (IoT), and artificial intelligence (AI) are effectively leading tools and ICT environments to help worldwide leadership, facilitators, and learners with quick, effective, and healthy interaction towards a sustainable development. This study investigated the principals’ integration of ICT in curriculum implementation for sustainable development. The respondents of the study consisted of 263 principals in public secondary schools in Anambra State. The study used descriptive survey design. The findings of the study revealed among others that lack of modern ICT facilities, poor internet network, poor maintenance culture, budgetary constrain of ICT personnel are the challenges. Based on the findings, it was recommended among others that Government should equip schools with ICT facilities, provides fund for training of ICT personnel for sustainable development.
Teachers’ Mindsets in Foreign Language Classrooms
Authors: OLDAÇ Betül , AYDIN Selami
Published: April 2023

This research aims to explore English teachers’ mindsets and further investigate whether teachers’ mindsets have anything to do with nine factors, namely, age, gender, the highest level of education completed, department graduated in, being abroad for education, receiving in-service training programs, teaching experience, level taught, and institution. In this descriptive study, data were collected from 162 English teachers working at geographically diverse institutions in Turkey through an online survey. The survey included a background questionnaire and a mindset instrument. Findings showed that more than half of the English teachers had a fixed mindset, and the remaining had either a mixed or a growth mindset, of which the latter constituted the smallest group in number. Results also revealed that teachers’ mindsets were irrespective of nine previously determined variables.
Linguoculturological Character of Somatic Phraseological Units with the “Head” Component (based on Turkic (Kazakh, Tatar, Bashkir) and English)
Authors:   Khoja Akhmet Yassawi International Kazakh-Turkish University, Sagidolda G.S. , Abdimaulen G.A. ,   Khoja Akhmet Yassawi International Kazakh-Turkish University
Published: April 2023

The aim of the work is to be guided by the anthropological position of «the human factor in language» in the anthropocentric paradigm of modern scientific research, the study of the concept of «language is a constitutional property of a person» through language, the formation of a holistic theory and theoretical and methodological form of unity of «language and man, language and the world». In this regard, the main focus and significance of the article is to consider the language from the point of view of the «language code» through the triad «human studies – language – World Studies». The authors pay special attention to the vision and cognition of the world, understanding and perception of the world by the Kazakh, Tatar, Bashkir and English peoples, as well as to ensure that the world of images and standards, stereotypes and symbols in the context of cultural traditions is reflected in the language and fixed in the meaningful subtext of language units in the form of background knowledge. The article analyzes the somatic phraseology of the «head» component in the linguistic and cultural aspect. Through them, the similarities and identities of the representatives in the systems of figurative thinking, attempts to know the world, life experience, customs and consciousness are revealed and were used as the material of the article. The analysis of the content of phraseological units related to the triad «Humanity – Language – World Science» has been carried out. The article uses the method of comparing somatic phraseological units at the inter-lingual level. The results of the study – in the semantic and substantive structure of somatic phraseology, presented in different languages, an archaic knowledge base is accumulated, which is caused by a person's self-awareness and the desire to thoroughly know other objects in the world through himself. The practical value of the work is the study of national and cultural features that contribute to the implementation of intercultural, interethnic communication between related and non-related languages. In the conclusion of the work, the somatism «head» is divided into several categories. The phrases used in Turkic and English languages reveal a lot of similarities in the ways and semantic features of the word «head». In particular, if the similarities between the Turkic languages say that their tendency to exist is due to a common culture, the phraseology used in unrelated Turkic and English languages shows evidence that the function of the «head» in any people is to the same extent.
LEXICAL-SEMANTIC SYSTEM OF WORDS COMMON IN MODERN TURKISH AND KAZAKH
Authors:   K. Zhubanov Aktobe Regional University, MURATBEK B.K.
Published: April 2023

The article examines the vocabulary (according to the materials of lexicographic works), lexical usage and semantics, semantic structure of polysemantic words and linguistic-semantic features that indicate the integrity of the Turkic world. The national composition of the modern Turkish population, attempts to learn Kazakh and Turkish languages, the degree of names and spelling, the same meaning or the same meaning of names in the Kazakh and Turkish languages, and degrees of discrepancy (mismatching), among them the question of which language is used by residents of the region in priority order is considered. The aim of the article is to determine the amount of common vocabulary in the Kazakh and Turkic languages and to conduct a comparative study of their meanings, to identify the difficulties arising in teaching the two languages as the foreign language words whose meanings are changed, to show the Turkic basis of common vocabulary, to analyze the change of meaning using comparative and historical method. The scientific significance and practical of the article lie in the fact that the linguistic data, evaluation (prediction) of some words in the past and future in a practical sense, the availability of conclusions, the validity and scientificity of judgments and conclusions were not previously known, and if they were known, they were collected in practice and analyzed in a scientific sense as a special object of research. As a result of the research, in order to study lexical-semantic processes in related languages, it is necessary to consider them in comparative and historical-comparative aspects.
CRITERIA-BASED ASSESSMENT MODEL IN THE EDUCATION SYSTEM OF KAZAKHSTAN
Authors:   Universitas Negeri Yogyakarta, Begimbetova G. , Kassymova G. ,   Abai Kazakh National Pedagogical University; Satbayev University, Abduldayev Ye. ,   Suleyman Demirel University
Published: April 2023

The article deals with the problems of using the Criteria-based Assessment Model in Kazakhstan's education system. The Criteria-based Assessment Model uses specific quantitative indicators of students' understanding of the curriculum, an objective and reliable assessment of students' knowledge and achievements. This assessment system enables teachers to identify and evaluate each student's strengths and weaknesses, assess their learning needs and achieve educational goals. Additionally, it allows for targeted learning, feedback, and compliance with international standards. The Criteria-based Assessment Model aims to enhance student motivation and engagement through formative and summative evaluations. The formative assessment provides ongoing feedback and support while the summative assessment evaluates the overall curriculum at each stage of academic study and at the end of the year. The research uses a quantitative approach to assessing criteria. The Criteria Assessment Model demonstrates the quality of English language proficiency of secondary school students in the second quarter through formative and summative evaluations. It helps teachers in Kazakhstan's education system to achieve students' academic success and the objective of controlling and evaluation.