bluuebunny/crossref_metadata_2025 huggingface dataset:
Russian Version of the International Trauma Questionnaire: Adaptation and Validation in a Non-Clinical Sample
Authors: Padun M.A. , Bykhovets J.V. , Kazymova N.N. , Ccentsova-Dutton Y.
Published: October 2022

Purpose. The article presents the results of adaptation and validation of the International Trauma Questionnaire (ITQ) on a Russian sample. The questionnaire measures the symptoms of complex post-traumatic stress disorder (CPTSD), which can develop as a result of exposure to prolonged, repetitive traumatic experiences in the interpersonal sphere. Method. The study was carried out on a non-clinical sample, which included 429 participants who were 18 to 68 years old and who experienced at least one traumatic event in their lives. International Trauma Questionnaire (ITQ), LEC-5 (Life events checklist-5), author’s questionnaire “Emotional abuse”, Symptom Checklist (SCL-90-R) were used in the study. Results. The structure of the questionnaire in the Russian-speaking sample confirmed the two-factor model of complex PTSD, which combines the symptoms of PTSD («Re-experiencing», «Avoidance», «Sense of Threat») and disturbances of Self-organization («Affective Dysregulation», «Negative Self-concept», «Disturbances in Relationships»). Internal consistency of the scale was in the acceptable range. Among those who have experienced at least one traumatic event, 20% met criteria for PTSD (11%) or CPTSD (9%). These data show that respondents with CPTSD have more intense psychopathological symptoms than respondents with PTSD; women show more intense symptoms of CPTSD than men.
Alzheimer hastalığı klinik ölçütlerine göre demans ve hafif kognitif bozukluk ayrımında sözel akıcılık testlerinin mini mental durum testi ile birlikte kullanılması yararlı olabilir
Authors: ÖZ Didem , ÖZBEK İŞBİTİREN Yağmur , KIYI İlayda , YENER Görsev
Published: October 2022

Amaç: Demans tarama ve tanısı için klinik pratikte sıklıkla kısa tarama testleri kullanılmaktadır. Mini Mental Durum Testi (MMDT) en sık kullanılan testlerin başında gelmektedir. MMDT’nin demans için duyarlı olduğu bilinmektedir. Ancak, sağlıklı yaşlanma ile demans arasında bir geçiş evresi olarak kabul edilen Hafif Kognitif Bozukluk (HKB)’un ayırt edilmesinde ve Alzheimer Hastalığı tipi demans (AHD) ile HKB’nin ayırıcı tanısında MMDT çoğu zaman yeterli olmamaktadır. Kısa sürede uygulanabilen sözel akıcılık testleri (semantik ve fonemik) MMDT’ye alternatif ya da MMDT ile kullanıldığında HKB ve AH’nin erken evreleri için tanısal doğruluğu daha yüksek bir tarama testi elde edilebilir. Bu çalışmanın amacı MMDT, semantik ve fonemik akıcılık testlerinin ROC eğrisi analizleri ile belirlenen duyarlılık, özgüllük ve kesme puanı değerlerinin sunulmasıdır. Gereç ve Yöntem: Çalışmaya yaş-eğitim-cinsiyet açısından uyumlu 72 sağlıklı birey, 72 HKB ve 72 AHD’li birey dahil edilmiştir. Tüm katılımcılara MMDT, semantik ve fonemik akıcılık testleri uygulanmıştır. ROC eğrisi analizleri ile MMDT, semantik ve fonemik akıcılık testlerinin sağlıklı, HKB ve AHD’li bireyleri ayırt etmedeki duyarlılık ve özgüllük değerleri ile kesme puanları elde edilmiştir. Bulgular: ROC analizleri her üç testin de sağlıklı, AHD ve HKB’li bireyleri istatistiksel olarak anlamlı şekilde ayırt edebildiğini göstermektedir. ROC eğrisi altında kalan alanlar karşılaştırıldığında MMDT’nin ayırt etme gücünün sözel akıcılık testlerinden yüksek olduğu görülmüştür. AHD ve HKB’li bireylerin ayrımında semantik akıcılığın özgüllüğü MMDT ve fonemik akıcılıktan yüksek bulunmuştur. Sonuç: Çalışmanın bulguları MMDT’nin sağlıklı bireyleri ayırt etmede semantik ve fonemik akıcılıktan daha güçlü olduğunu, ancak HKB ve AH ayrımında özgüllüğünün semantik akıcılıktan düşük olduğunu göstermektedir. Tanı doğruluğunun artırılması için kısa zamanda uygulanabilen sözel akıcılık testlerinin, özellikle semantik akıcılık testinin klinik pratiğe eklenmesi yararlı olabilir.
Multi-Event Explosive Seismic Source for the 2022 Mw 6.3 Hunga Tonga Submarine Volcanic Eruption
Authors: Thurin Julien , Tape Carl , Modrak Ryan
Published: October 2022

The eruption of the Hunga Tonga–Hunga Ha’apai submarine volcano on 15 January 2022 produced a variety of geophysical responses, including a significant seismic signal. We study the seismic source process of this event by inverting for moment tensors (MTs) using regional surface waves (Rayleigh, Love). By comparing inversion results for the eruption with eight nearby earthquakes, we show that it is possible to discriminate MT source types. Our inversion yields a shallow explosive source for the eruption and reveals the importance of trade-offs among depth, magnitude, and source type. We illustrate these trade-offs by representing the misfit variations over the eigenvalue lune. Finally, we invert for the source-time function of the sequence of explosions that occurred in the first minutes of the eruption. The multi-event source-time function comprises four subevents spanning ∼270 s, with a total magnitude estimate of Mw 6.34 ± 0.10.
German Animal Protection Societies in the 1840s and 1850s: Anthropocentric Perceptions and their Alternatives
Authors:   The Korean Society For German History, Song Chungki
Published: October 2022

Animal Protection Societies (Tierschutzverein) in Germany were established around 1840 and their conceptions were basically anthropocentric. But over time the emphasis on compassion (Mitleid) for pains of animals and the growing experience with animals led to the recognition that there were significant similarities between humans and nonhuman animals. The aim of this article is to show how widely this perception was spread among the activists of the Animal Protection Societies before scientific researchers such as Darwin postulated it and the culture of companion animals came in. It concludes that some activists already argued that the differences between humans and nonhuman animals were not so great as they were earlier assumed. Particularly they held that humans and nonhuman animals shared the same traits in terms of feelings.
Mapping Intercultural Communication Imperatives of Police-Public Interactions in Rural Spaces
Authors: Ndhlovu Finex , Mulrooney Kyle , Mutongwizo Tariro , Harkness Alistair
Published: October 2022

This research note seeks to generate fruitful pathways to advance a new discourse on intercultural encounters between the police and individuals from multilingual communities in Australia’s increasingly diverse rural and regional settings. How might police officers better relate and communicate with groups of migrants whose language practices are complex, unpredictable and eschew the widely used logics of translation and interpretation? How might we encourage hope in our social communities that intercultural understanding between policing agencies and new migrants is key to co-creating peaceful and resilient rural communities? How might police communication protocols that assist in supporting the retention of migrants’ linguistic capabilities and funds of knowledges contribute to the wellbeing of regional communities? What would policing rural and regional communities look like if we were to centre sociolinguistic and intercultural imperatives? In this research note, we consider these questions in our search for the next steps in mapping police communication protocols that work for all in Australia’s rural and regional settings. The goal is to contribute new conceptual approaches we can use to foster partnerships and trusting relationships between the police and our increasingly diverse rural populations.
Entrando por la otra puerta: la indagación para promover el razonamiento científico en educación infantil
Authors: Pérez-Martín José Manuel , Salvadó Zoel , Sánchez-Ferrezuelo Lorena , Gairal-Casadó Regina , Novo Maite
Published: October 2022

La percepción negativa hacia la enseñanza de las ciencias agrava otras que incrementan la dimensión excluyente del aprendizaje de las ciencias (diversidad de género, étnica, socio-económica, cultural, etc.). Por ello, quisimos valorar las percepciones sobre la ciencia y su enseñanza en docentes y estudiantes (5-6 años) de Educación Infantil, a través de entrevistas, tras la implementación en el aula de una secuencia de actividades basadas en indagación. Observamos que los maestros cambian su percepción sobre la ciencia al ver una herramienta didáctica que presenta la ciencia como algo que se construye participativamente y por la que muestran gran interés sus estudiantes. La desafección previa se debe a su escaso dominio del contenido y del conocimiento didáctico del contenido adquirido durante su formación. Al finalizar, se interesan por implementar actividades similares con materiales preparados. No se detectan barreras que limiten la percepción positiva de la ciencia entre los estudiantes. Por tanto, parece que la enseñanza de las ciencias basada en la indagación es una estrategia didáctica que mejora la percepción de las ciencias en EI, eliminando barreras de exclusión, convirtiendo a los maestros en pieza clave de la dimensión transformadora para la enseñanza de las ciencias en etapas tempranas.
El co-diseño didáctico entre escuela y universidad: avanzando hacia una educación transformadora
Authors: Berbel-Gómez Noemy , Pérez-Garcias Adolfina , Darder-Mesquida Antònia
Published: October 2022

El enfoque educativo basado en diseño (co-diseño), puede representar un modelo para la formación inicial y permanente del profesorado. En este artículo se presenta una experiencia que pretende, por una parte, ofrecer a los estudiantes del Grado de Educación Primaria propuestas formativas situadas y de calidad a través del co-diseño didáctico –con maestros del centro y docentes universitarios– y su implementación y, por otra, promover en la escuela experiencias educativas transformadoras. Se ha realizado un estudio de la satisfacción de los agentes implicados en el proyecto, mediante análisis de contenido de la información recogida a través de diferentes técnicas (cuestionario, relato y observación). En la experiencia participaron 2 maestras, 7 estudiantes del Grado de Educación Primaria, 3 profesoras de dichos estudios y 23 estudiantes de 5º de primaria. Los resultados muestran un alto grado de satisfacción en todas las dimensiones del estudio: implicación en el proceso, utilidad y proyección de los aprendizajes. Se concluye que el enfoque y metodología didáctica han reportado aprendizajes profundos y alta motivación en los futuros docentes y han supuesto elementos de reflexión e impulso a la práctica educativa transformadora.
Reviving the Cultural Route and Its Role in the Sustainability of Historical Areas - Kerbala as a Case Study
Authors: Al-Jaberi Zaman Auda , Hasan Shatha A.
Published: October 2022

Cultural heritage represents one of the most important resources for development processes, and cultural routes as cultural elements have the potential to revitalize and develop the historical area sustainably by stimulating cultural tourism. One aspect of cultural tourism is to provide cultural itineraries for visitors that enable them to explore the cultural heritage of the host region. The literature in this field has dealt with the potential of heritage in general in providing meaning and value to the environmental, and socio-economic aspects that form the foundations of sustainable development. This paper uses a multidisciplinary approach to study the possibility of designing and reviving cultural routes as catalysts for historical revitalization. Taking the Cultural Routes in (Karbala) as an example, the network and node perspective model are adopted to determine two historic tourism routes in this region. And it turns out that the preservation and protection policies for heritage must be integrated manner with the development processes, and to achieve a balance between the aspects of sustainable development and emphasize their interrelation and interaction with the historical environment.
An Exploration and Comparison of Attitudes Towards the Participatory Solid Waste Management for Sustainable Development of Communities in Khaoroopchang Municipality, Songkhla Province, Thailand
Authors: Kaewprapun Wassawadee , Muensit Ampai , Maliwan Ekarach , Kangkha Patcharin , Suphattanakul Onuma
Published: October 2022

The purpose of this study is to explore and compare the community members’ attitudes towards community participation in solid waste management. The participants in this research were 400 people in 3 communities in Khaoroopchang Municipality. The research instrument was a set of 5-point rating scale questionnaires, enquiring about the community members’ attitudes towards the community’s solid waste management. The statistics used for data analysis were mean, standard deviation, t-test, analysis of variance (ANOVA), and LSD pairwise comparison. The results revealed that the community members’ attitudes towards the participatory solid waste management were at a high level. The results also showed that people who had different ages, education, occupations, residences, and family incomes had different attitudes towards waste management. This research outcome serves as a guideline for community leaders in changing the behavior of each household in the community in terms of waste sorting, career enhancement, and increasing income in the community in order to be good role models and local philosophers for sustainable development.
«Mirror Metamorphoses» in Comparative Phenomenology of Clarification of Mind
Authors:   Saratov State Technical University, Duplinskya Y. M.
Published: October 2022

Article is devoted the comparative analysis of phenomenological experience of «pure consciousness» in various traditions, as sacral, and деsаcranunted. Various updatings of symbolics of a mirror in which result similar receptions «mind clarifications» in phenomenological experience of different traditions are compared. Specificity of experience of Orthodoxy in its relation to mirror symbolics is considered.
Pedagogical Activity on the Organization of Youth Self-Governance at a Faculty
Authors:   Saratov State University, Kurchatova N. Y.
Published: October 2022

The article considers the concept of «youth» and the specificity of the development of this age group within society and university. The author points out that the students of a faculty are a specific youth group, which needs to focus on their own development, as well as in need of support and acceptance by the group of peers and self-fulfillment in it. On this basis, one of the directions of pedagogical activity at a faculty is the creation of the students’ self-government, the center of which should become a student council as a strong organizational core.
Theoretical and Methodological Grounds of Sport Activity Research
Authors:   Southern Federal University, Bogdanova M.A.
Published: October 2022

Author considers that it is impossible to describe sport activity sufficiently within the approaches used in studying physical culture traditionally. Author suggests a humanitarian view on sport. It means researching in sport and sport activity from a position of sense. The method of studying sport from sense position, analyzing of its value content allows considering the nature of sport more deeply.
Fatherhood as a Problem of Social Philosophy
Authors:   Saratov State University, Butaev M.V.
Published: October 2022

The paper studies fatherhood as a problem of social philosophy, viewed through the realization of the social and historic circumstances and peculiarities of fathers and children’s relations building. Philosophic analyses of the category brings to the surface the sources of fatherhood based in the human social existence. The analyses reveals a specific way of fatherhood institution transformation in Russia and gives reasons for it’s crisis in the context of the social risky power environment.
Transformation of Representations about the Responsibility During Professional Socialization of Lawyers
Authors:   Saratov State University, Sotnikov A. E.
Published: October 2022

In article are presented the results of the empirical researches of changes of representations about the responsibilityduring the professionalization of lawyers. The author reveals proof and significant interrelations of representations various at different stages of professional socialization.
What About Us? Global Perspectives on Redressing Religious Inequalities
Authors:   Institute of Development Studies, Aderounmu Olumide Adebimpe , Aqeel Asif , Ahmed (Elehemier) Manal , Feldmann Kaye Miriam , Gill Mary , Kaahwa Mark , Mader Philip , Makgoba Matome Jacky , Muhumuza Moses , Shah Rebecca Supriya , Shah Timothy Samuel , Tadros Mariz , Thane Katharine , Tifloen Rifqah , Vanwing Tom
Published: October 2022

How can we make religious equality a reality for those on the margins of society and politics? This book is about the individual and collective struggles of the religiously marginalised to be recognised and their inequalities, religious or otherwise, redressed. It is also about the efforts of civil society, governments, multilateral actors, and scholars to promote freedom of religion or belief (FoRB) whatever shape they take. The actors and contexts that feature in this book are as diverse as health workers in Israel, local education authorities in Nigeria, indigenous movements in India, Uganda, or South Africa, and multilateral actors such as the Islamic Development Bank in Sudan and the World Bank in Pakistan. Some of the case studies engage with development discourses and narratives or are undertaken by development actors, while other cases operate completely outside the international development paradigm. These case studies present some important insights, which while highly relevant for their contexts also draw out important insights for academics, practitioners, activists, and others who have an interest in redressing religious inequalities for socioeconomically marginalised populations.
Assessing and managing the environmental and social impact of coffee production
Authors:   University of Bonn, Germany, Pohlan H. A. Jürgen , Janssens Marc J. J. ,   University of Bonn, Germany, Salazar Centeno Dennis José ,   Universidad Nacional Agraria Managua, Nicaragua
Published: October 2022

This chapter reviews ways of measuring and improving the sustainability of coffee production systems, including good agricultural practices (GAP), life cycle assessment (LCA), ways of calculating the carbon footprint of coffee as well as methods for assessing social impacts. It also discusses ways of improving sustainability in the coffee value chain, particularly by understanding and optimizing coffee production as an agroecosystem. The chapter reviews techniques to support agroecosystem function and resilience such as shade, soil and biodiversity management.
Specialty coffees as drivers of change
Authors:   University of Bonn, Germany, Pohlan H. A. Jürgen , Salazar Centeno Dennis José ,   UNA Managua, Nicaragua, Torrico-Albino Juan Carlos ,   UMSA La Paz, Bolivia, Janssens Marc J. J. ,   University of Bonn, Germany
Published: October 2022

This chapter reviews the role and importance of specialty coffees. It looks at the emergence of the sector and issues of definition, whether in terms of sensory quality attributes such as a unique flavor, geographical origin or methods of production. As well as factors affecting pricing, it reviews the role of geographical indicators and, in particular, the importance of good agricultural practices (GAP) in standardizing, improving and validating the quality attributes that underpin specialty coffees.
On stability and continuous dependence on parameter of the set of coincidence points of two mappings acting in a space with a distance
Authors: Zhukovskaia Tatiana V. , Merchela Wassim
Published: October 2022

We consider the problem of coincidence points of two mappings ψ,φ, acting from a metric space (X,ρ) into a space (Y,d), in which a distance d has only one of the properties of the metric: d(y_1,y_2)=0⇔y_1=y_2, and is assumed to be neither symmetric nor satisfying the triangle inequality. The question of well-posedness of the equation
ψ(x)=φ(x),
which determines the coincidence point, is investigated. It is shown that if x=ξ is a solution to this equation, then for any sequence of α_i-covering mappings ψ_i:X→Y and any sequence of β_i-Lipschitz mappings φ_i:X→Y, α_i>β_i≥0, in the case of convergence d(φ_i (ξ),ψ_i (ξ))→0, equation ψ_i (x)=φ_i (x) has, for any i, a solution x=ξ_i such that ρ(ξ_i,ξ)→0.
Further in the article, the dependence of the set "Coin"(t) of coincidence points of mappings ψ(•,t),φ(•,t):X→Y on a parameter t, an element of the topological space T, is investigated. Assuming that the first of these mappings is α-covering and the second one is β-Lipschitz, we obtain an assertion on upper semicontinuity, lower semicontinuity, and continuity of the set-valued mapping "Coin":T⇒X.
The role of mitochondria in the pathogenesis of the "complex" wound process
Authors: Supilnikov A. A. , Ledovskikh E. A. , Dzhamalova N. M. , Trusova L. A. , Starostina A. A. , Yunusov R. R. , Yaremin B. I.
Published: October 2022

Wound healing is a complex biological process involving various cells, mediators, and components of the extracellular matrix involved in the processes of coagulation, inflammation, angiogenesis, epithelialization, and fibroplasia. Wound healing is described by four interrelated phases: hemostasis, inflammation, proliferation and remodeling. Each of the phases has its role at the molecular and tissue levels, and if a defect occurs in the chain of one of the phases of the wound healing process, the healing process is disturbed and a chronic wound condition occurs. Various factors such as infections, arterial and venous circulatory disorders, type 2 diabetes and chronic inflammation contribute to this. Prolonged non-healing wounds represent an urgent problem of modern medicine. Oxidative stress plays a crucial role in the pathogenesis of chronic wounds. In this review the pathogenesis of chronic wounds and its involvement of reactive oxygen species (ROS), oxidative stress, the role of mitochondria in ROS generation as well as the prospects of mitochondrial-directed antioxidants in the treatment of chronic wounds are considered.
Association of IL – 23 R rs 7518660 Gene Polymorphism with Susceptibility and Disease Severity of Pulmonary Tuberculosis
Authors: Widowati Yenny , Sugiri Yani Jane , Putu Ngakan , Setijowati Nanik
Published: October 2022

Pulmonary Tuberculosis (TB) is a global health problem. Of all people infected with Mycobacterium tuberculosis only a small proportion develops into TB. IL 23 is the key cytokine in the pathogenesis of TB infection. This study aims to determine the association of IL-23 R rs 7518660 gene polymorphism with susceptibility and disease severity of Pulmonary TB. A case control study involved 105 people consisting of 31 drug sensitive pulmonary TB patients, 40 patients with drug-resistant pulmonary TB and 34 healthy subjects as a control. IL-23 R rs 7518660 gene polymorphism G allele increases susceptibility to both TB drug-sensitive and drug-resistant. G and A allele, AA and AG genotypes indicates (p value >0.05) in correlation with disease severity based on lesion in chest x-ray and high load of Mycobacterium tuberculosis in sputum. There was a significant relationship between allele A and susceptibility to pulmonary TB with an odds ratio of 0.231. It showed that patients with A alleles (AG and AA genotypes) were at risk of developing TB by 1/0.231 = 4.33 times lower than patients with GG genotypes. Meanwhile, the relationship of the G allele with susceptibility to pulmonary TB obtained (p value <0.05) and an odds ratio value of 0.127 indicating that patients with G alleles (GG and AG genotypes) were at risk of developing TB of 1/0.127 = 7.87 times higher than in patients with the AA genotype. Conclusion: We found significant correlation between IL-23 R rs 7518660 gene polymorphism G allele with susceptibility to pulmonary TB, but the result was not significant with disease severity.
Clinical Profiles, Laboratory, Radiological and Outcome of COVID-19 Elderly Patients in Waikabubak Regional General Hospital, West Sumba
Authors: Laurentia Lisbeth Maria , Effendi Rambu Farah
Published: October 2022

Cases of COVID-19 in the elderly show varied clinical characteristics. Elderly patients tend to be easily infected with COVID-19 and experience more severe conditions. This study aims to analyze the correlation between clinical characteristics of elderly COVID-19 patients and severity of COVID-19 disease at Waikabubak Regional General Hospital. Retrospective study from the medical records of elderly patients with confirmed COVID-19 at Waikabubak Regional General Hospital in March 2020 – September 2021. Inclusion criteria were elderly patients with confirmed COVID-19 who underwent treatment in COVID isolation room and did rapid antigen examination. The data collected were demographics, clinical manifestations, laboratory, radiological features, comorbid, and outcomes. Data analysis using SPPS for Window 12.0 version. There were 33 patients with 18 men and 15 women. Patients aged 65-74 are the most infected with COVID-19 and experience more severe conditions. Patients with no previous vaccine history were associated with the severity of COVID-19. Elderly patients with obesity tend to experience severe COVID-19 symptoms. Elderly patients with multi-comorbidities tend to experience severe COVID-19 symptoms. Dominant clinical symptoms in elderly patients were cough (33%), shortness of breath (25%) and fever (21%). Hematologic parameters that correlated with severity were hemoglobin, platelets, NLR, ALC and RBG. The most common radiological findings were bilateral infiltrates (92%). Mortality rate of elderly COVID-19 patients treated at the Waikabubak Regional General Hospital still tends to be high (42%). Age, vaccine history, obesity, shortness of breath, multi-comorbidities, laboratory and radiology significantly influence the severity of COVID-19 infection in the elderly.
Knowledge and Attitudes of Dengue Virus Infection Transmission and Its Relationship with Eradication Action Program in Surabaya, Indonesia
Authors: Juliasih Ni Njoman , Sucipto Teguh Hari , Sari Reny Mareta , Nuha Zakiyathun , Soegijanto Soegeng
Published: October 2022

Dengue virus infection is caused by a dengue virus transmitted through mosquito bites from species Aedes albopictus and Aedes aegypti. The Ministry of Health takes action to reduce the prevalence of DHF by regulating the management of PSN 3M Plus. This study aimed to determine the knowledge, attitude, and compliance with the management of PSN 3M Plus strategies of those living in Surabaya. A cross-sectional population-based google form questionnaire was conducted in January 2022 for four weeks (January 3, 2022, to January 29, 2022). Based on the bivariate analysis, gender and age of respondents were no relationship between compliance with the PSN 3M Plus (p-value >0.05). The results also showed no relationship between education and adherence to PSN 3M Plus (p-value > 0.05). However, based on previous studies, people with higher education showed better compliance. Public knowledge and attitude about the dengue virus and its transmission process can be increased by developing, modifying, and intervening in the people controlling dengue virus infection. Most people of Surabaya believe that dengue prevention is the complete responsibility of every people. Based on the bivariate analysis, the characteristics of respondents had no relationship with the PSN 3M Plus compliance  (p-value > 0.05). Knowledge and attitudes of the Surabaya people toward PSN 3M Plus are still good. However, the characteristics of the respondents did not significantly affect their knowledge and attitudes
Understanding the role of interfaces in solid-state lithium-sulfur batteries
Authors: Tao Tao , Zheng Zhijia , Gao Yuxuan , Yu Baozhi , Fan Ye , Chen Ying , Huang Shaoming , Lu Shengguo
Published: October 2022

All-solid-state lithium-sulfur batteries (ASSLSBs) exhibit huge potential applications in electrical energy storage systems due to their unique advantages, such as low costs, safety and high energy density. However, the issues facing solid-state electrolyte (SSE)/electrode interfaces, including lithium dendrite growth, poor interfacial capability and large interfacial resistance, seriously hinder their commercial development. Furthermore, an insufficient fundamental understanding of the interfacial roles during cycling is also a significant challenge for designing and constructing high-performance ASSLSBs. This article provides an in-depth analysis of the origin and issues of SSE/electrode interfaces, summarizes various strategies for resolving these interfacial issues and highlights advanced analytical characterization techniques to effectively investigate the interfacial properties of these systems. Future possible research directions for developing high-performance ASSLSBs are also suggested. Overall, advanced in-situ characterization techniques, intelligent interfacial engineering and a deeper understanding of the interfacial properties will aid the realization of high-performance ASSLSBs.
A Duality Principle and a Related Convex Dual Formulation Suitable for Global Non-Convex Variational Optimization
Authors: Botelho Fabio
Published: October 2022

This article develops a duality principle and a related convex dual formulation suitable for the global optimization of a non-convex primal formulation for a large class of models in physics and engineering. The results are based on standard tools of functional analysis, calculus of variations and duality theory. In particular, we develop applications to a Ginzburg-Landau type equation.
Altered Cortical Palmitoylation Induces Widespread Molecular Disturbances in Parkinson´s Disease
Authors: Cervilla-Martinez Juan F. , Rodriguez-Gotor Juan J. , Wypijewski Krzysztof J. , Fontán-Lozano Ángela , Wang Tao , Santamaría Enrique , Fuller William , Mejías Rebeca
Published: October 2022

The relationship between Parkinson's disease (PD), the second most common neurodegenerative disease after Alzheimer's disease, and palmitoylation, a post-translational lipid modification, is not well understood. In this study, we have analyzed the differential palmitome present in the cerebral cortex of PD patients compared to controls (n=4 per group) to better understand the role of protein palmitoylation in PD and the pathways altered in this disease. Data-mining of the cortical palmitome from PD patients and controls has allowed to: i) detect a set of 150 proteins with altered palmitoylation in PD subjects in comparison with controls, ii) describe the biological pathways and targets predicted to be altered by these palmitoylation changes, and iii) depict the overlap between the differential palmitome identified in our study with protein interactomes of the PD-linked proteins α-synuclein, LRRK2, DJ-1, PINK1, GBA and UCHL1. In summary, we have partially characterized the altered palmitome in the cortex of PD patients which is predicted to impact cytoskeleton, mitochondrial and fibrinogen functions, as well as cell survival. Our study points out that protein palmitoylation could have a role in the pathophysiology of PD, and that comprehensive palmitoyl-proteomics offers a powerful approach for elucidating novel cellular pathways modulated in this neurodegenerative disease.
Using Drones with Thermal Imaging to Estimate Population Counts of European Hare (Lepus europaeus) in Denmark
Authors: Povlsen Peter , Linder Anne Cathrine , Larsen Hanne Lyngholm , Durdevic Petar , Arroyo Daniel Ortiz , Bruhn Dan , Pertoldi Cino , Pagh Sussie
Published: October 2022

Drones equipped with thermal cameras have recently become readily available, broadening the possibilities for monitoring wildlife. The European hare (Lepus europaeus) is a nocturnal mammal that is closely monitored in Denmark due to populations declining since the mid-1900s. The limitations of current population assessment methods, such as spotlight counts and hunting game statistics, could be overcome by relying on drone surveys with thermal imaging for population counts. The aim of this study was to investigate the use of a DJI Mavic 2 Enterprise Advanced drone with thermal imaging as a tool for monitoring the Danish hare population. Multiple test flights were conducted over agricultural areas in Denmark in spring 2022, testing various flight altitudes, camera settings, and recording methods. The test flights were used to suggest a method for identifying and counting hare. The applied use of this methodology was then evaluated through a case survey that had the aim of identifying and counting hare over an agricultural area of 242 ha. Hare could be detected with thermal imaging at flight altitudes up to 80 m and it was possible to fly as low as 40 m without observing direct behavior changes. Thermal images taken at these altitudes also provided enough detail to differentiate between species and animal body size proved to be a good species indicator. The case study confirmed the use of thermal imaging based drone surveys to identify hare and conduct population counts, thus, indicating the suggested methodology as a viable alternative to traditional counting methods.
Social Behavior and COVID-19: Analysis of the Social Factors behind Compliance with Interventions across the United States
Authors: Maleki Morteza , Bahrami Mohsen , Menendez Monica , Balsa-Barreiro Jose
Published: October 2022

Since its emergence, COVID-19 has caused a great impact in health and social terms. Governments and health authorities have attempted to minimize this impact by enforcing different mandates. Recent studies have addressed the relationship between various socioeconomic variables and compliance level to these interventions. However, little attention has been paid to what constitutes people's response and whether people behave differently when faced with different interventions. Data collected from different sources show very significant regional differences across the United States. In this paper, we attempted to shed light on the fact that a response may be different depending on the health system capacity and each individuals’ social status. For that, we analyzed the correlation between different societal variables (i.e. education, income levels, population density, etc.) along with healthcare capacity related variables (i.e. hospital occupancy rates, percentage of essential workers, etc.) with regards to people's level of compliance with three main governmental mandates in the United States: mobility restrictions, mask adoption, and vaccine participation. Our aim was to isolate the most influential variables impacting behavior in response to these policies. We found that there was a strong relationship between individuals' educational levels and political preferences with respect to compliance with each of these mandates.
Periodontal Tissue Regeneration by Recombinant Human Collagen Peptide Granules Applied With β-Tricalcium Phosphate Fine Particles
Authors: Yoshino Yuto , Miyaji Hirofumi , Nishida Erika , Kanemoto Yukimi , Hamamoto Asako , Kato Akihito , Sugaya Tsutomu , Akasaka Tsukasa
Published: October 2022

Recombinant human collagen peptide (RCP) is a recombinantly created xeno-free biomaterial enriched in RGD (arginine-glycine-aspartic acid) sequences, with good processability that is being investigated for regenerative medicine applications. Recently, the biocompatibility and osteogenic ability of β-TCP/RCP (RCP granules combined with β-tricalcium phosphate (TCP) submicron particles) were demonstrated. In the present study, β-TCP/RCP was implanted into experimental periodontal tissue defects (three-walled bone defect) created in beagle dogs to investigate tissue responses and subsequent regenerative effects. Micro computed tomography image analysis at 8 weeks postoperatively showed that the amount of new bone after β-TCP/RCP graft was significantly greater (2.2 fold, P<0.05) than that of the control (no graft) group. Histological findings showed that the transplanted β-TCP/RCP induced active bone-like tissue formation including TRAP-positive and OCN-positive cells as well as bioabsorbability. Ankylosis did not occur, and periostin-positive periodontal ligament-like tissue formation was observed. Histological measurements revealed that β-TCP/RCP implantation formed 1.7-fold more bone-like tissue and 2.1-fold more periodontal ligament-like tissue than the control, and significantly suppressed gingival recession and epithelial downgrowth (P<0.05). These results suggest that β-TCP/RCP is effective as a periodontal tissue regenerative material.
The Complex World of Emaraviruses – Challenges, Insights and Prospects
Authors: Rehanek Marius , Karlin David G. , Bandte Martina , Al Kubrusli Rim , Nourinejhad Zarghani Shaheen , Candresse Thierry , Büttner Carmen , Von Bargen Susanne
Published: October 2022

: Emaravirus (Order Bunyavirales; Family Fimoviridae) is a genus comprising over 20 emerging plant viruses with a worldwide distribution and economic impact. Emaraviruses infect a variety of host plants and have especially become prevalent in important long-living woody plants. These viruses are enveloped, with a segmented, single-stranded, negative-sense RNA genome and are transmitted by eriophyid mites or mechanical transmission. Emaraviruses have four core genome segments encoding an RNA-dependent RNA polymerase, a glycoprotein precursor, a nucleocapsid protein, and a movement protein. They also have additional genome segments, whose number varies widely. We report here that the proteins encoded by these segments form three main homology groups: a homolog of the sadwavirus Glu2 Pro glutamic protease; a protein involved in pathogenicity, which we named “ABC”; and a protein of unknown function, which we named “P55”. The distribution of these proteins parallels the emaravirus phylogeny and suggests, with other analyses, that emaraviruses should be split into at least two genera. Reliable diagnosis systems are urgently needed to detect emaraviruses, assess their economic and ecological importance, and take appropriate measures to prevent their spread (such as routine testing, hygiene measures, and control of mite vectors). Additional research needs include understanding the function of emaravirus proteins, breeding resistant plants and clarifying transmission modes.
Eating Behavior and Nutritional Status in Spanish Schoolchildren
Authors: Calderón  García Andrea , Alaminos Torres Ana Maria , Tomé Roberto Pedrero , Prado Martínez Consuelo , Martínez Álvarez Jesús Román , Villarino Marín Antonio , Marrodán Serrano Maria Dolores
Published: October 2022

Background: Different investigations have shown an association between the eating behavior of children and adolescents, and their nutritional status. The objective is to identify eating behavior patterns associated with nutritional status diagnosed by anthropometry in a sample of Spanish schoolchildren. Methods: A cross-sectional study in 283 Spanish schoolchildren (6 to 16 years old). Methods: The sample was assessed anthropometrically by Body Mass Index (BMI), Waist-to height ratio (WHtR) and body fat percentage (%BF). Eating behavior was analyzed using the CEBQ "Children's Eating Behavior Questionnaire" answered by parents or guardians. Results: A positive association was found between excess weight, abdominal obesity, high adiposity, lower scores in anti-intake subscales and higher scores in pro-intake subscales. These were mainly associated with lower satiety response, higher food intake, higher food enjoyment, higher eating speed, and emotional overeating. Conclusion: Our results support the usefulness of the CEBQ as an easy-to-use tool to identify eating behaviors associated with the development of childhood and adolescent obesity. Its use in future research could help to understand behavioral phenotypes in schoolchildren and guide nutrition education and obesity prevention initiatives
Automatic Center Detection of Tropical Cyclone using Image Processing based on the Operational Radar Network
Authors: Mo Sun-Jin , Gu Ji-Young
Published: October 2022

This study presents the algorithm ACTION, defined as Automatic Center detection of Tropical cyclone (TC) using Image processing based on the Operational radar Network. Based on the high visibility of weather radar imagery, the TC’s motion vector is calculated from the continuous image change using optical flow, producing its rotation center as the TC’s center. The algorithm’s performance was verified for typhoons (TCs in the Northwestern Pacific) affecting the Korean Peninsula from 2018–2021 and showed a high detection rate of 80.8% within an error distance of 40 km compared to the best track of the Korea Meteorological Administration (KMA). The detection rate was 100% for typhoons with temporally consistent morphological characteristics. ACTION automatically generates TC center information upon the TC’s initial entry inside the observation radius even in the absence of uniform radar data. ACTION easily calculates using Open Source Computer Vision, performs in real time, and can be directly applied to rapidly generated weather radar images; hence, it is currently being utilized by the KMA. The high-temporal-resolution TC center information calculated through ACTION is expected to improve the efficiency of TC forecasting.
Streptavidin-Modified Iron Oxide Hybrid Nanozymes for Magnetic Enrichment and Bioelectrocatalytic Sensing of Circulating Tumor RNA
Authors: Koo Kevin M.
Published: October 2022

Iron oxide nanozymes are a form of nanomaterial with both superparamagnetic and enzyme-mimicking properties. Given the multifunctional nature of iron oxide nanozymes, it is attractive for creating iron oxide hybrid nanozymes through biomolecular modifications to imbue with auxillary properties. Such iron oxide hybrid nanozymes can be useful for rapid and cost-effective analysis of circulating tumor nucleic acids (ctNAs) in patient liquid biopsies during minimal residual disease (MRD) monitoring of cancer recurrence. Herein, the use of streptavidin-modified iron oxide hybrid nanozymes is reported for magnetic enrichment and bioelectrcatalytic sensing of three prostate cancer (PCa) ctRNA biomarkers with high detection specificity and sensitivity (10 copies) over an ultrabroad dynamic range (five orders of magnitude). Furthermore, the feasibility of ctRNA analysis for pre- and post-cancer treatment MRD monitoring is demonstrated using PCa urinary liquid biopsy samples.
Biothermodynamic Key Opens the Door of Life Sciences: Bridging the Gap between Biology and Thermodynamics
Authors: Popovic Marko
Published: October 2022

During the last 50 years, an interdisciplinary approach in research in various scientific fields has become widely spread. This process significantly deepens and widens our scientific knowledge, but on the other hand makes more difficult choosing a discipline to be used by students and young researchers. The dynamic development of science makes this choice even harder. There is a widely spread opinion that thermodynamics uses a rigorous mathematical apparatus. This paper describes that knowledge of the fundamental principles of thermodynamics is required for deep understanding of crucial biological processes. Thus the effort put into learning classical and nonequilibrium thermodynamics does not make harder, but easier gaining a better knowledge of biological processes. This essay is an attempt to convey personal experience in using thermodynamics to describe biological systems and processes they perform.
Ancient Schwannoma: A Case Report
Authors: Lee Sang-Houn , Park Geo Seong , Jang Hyoung-Gyu , Park Jung-Soo , Lee Jong-Myong , Koh Eun Jeong , Choi Ha-Young
Published: October 2022

Schwannomas are common, slow-growing benign tumors derived from Schwann cells lining the nerve sheath which are rarely developed from the scalp. There are several types of schwannoma; however, ancient schwannoma is a rare benign tumor. We present a case of a 36-year-old man with an approximately 3 × 2-cm palpable mass on the left parietal area of his scalp that slowly grew over 5 years. The tumor was surgically excised and confirmed by immunohistochemistry, indicating an “ancient schwannoma” different from a trichilemmal or dermoid cyst.
Effects of Antiplatelet Agents on Cerebral Vasospasm and Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage Patients Treated with Coil Embolization
Authors: Baek Ki Dong , Kim Jae Hoon , Kang Hee In , Bae In-Suk , Jwa Cheol Su
Published: October 2022

Objective: This study aimed to investigate the role of antiplatelet agents (APAs) in preventing cerebral vasospasm (CVS) and delayed cerebral ischemia (DCI) in aneurysmal subarachnoid hemorrhage (SAH) patients treated with coil embolization.Methods: We reviewced data from 131 consecutive patients who underwent coil embolization following aneurysmal SAH from January 2011 to May 2021. We finally recruited 108 patients and analyzed the occurrence of CVS and DCI, as well as the modified Rankin Scale (mRS) score at discharge according to the use of APA (APA group [n=32] vs. non-APA group [n=76]).Results: The baseline characteristics, except patient age, were not significantly different between the APA and the non-APA groups. DCI (p=0.846), transcranial Doppler ultrasonographic vasospasm (p=0.449), angiographic vasospasm (p=0.176), and mRS scores at discharge (p=0.194) were also not significantly different between the groups. Newly developed cerebral infarction was significantly more frequent in the APA group (p=0.027).Conclusion: APA use did not reduce the occurrence of CVS and DCI in aneurysmal SAH patients treated with coil embolization, indicating that the effect of APAs on clinical outcomes may be trivial compared with other risk factors.
Encryption Based Simple and Robust Subscriber – Client Authentication Protocol for Ultralightweight Sensor Networks
Authors: Chakraborty Rajdeep , Acharya Aheli , Paul Debasmita , Guha Debajyoti , Elngar Ahmed A.
Published: October 2022

Safety is the most important part of IoT networks. A maximum number of IoT devices are resource constrained, it is difficult to implement strong safety mechanisms. The maximum number of authentication techniques use certificates in which signing and verifying require additional computation and power. Thus, the goal of this paper is to propose a new lightweight encryption-based authentication protocol for resource-controlled devices. In this paper we proposed an authentication protocol that uses RRSC – v1 encryption and one subscriber and several clients. The main objective is to develop an ultralightweight protocol for a very low-resourced sensor network. In this protocol, we have two algorithms, first, one to one encryption-based authentication protocol where the client is the low resource sensor and the subscriber is the edge device in the IoT. Second, the RRSC – V1, encryption algorithm itself. It has many applications for temperature sensors, rain sensors, and smoke sensors as they have very low memories and computing capacity.
Development of a MOF-based SPE method combined with GC-MS for simultaneous determination of alachlor, acetochlor and pretilachlor in field soil
Authors: Cai Yjuan , Li Liying , Zhang Jun , Li Zhenjie , Zhang Fengmei , Xu Yanqun , Tai Zhigang
Published: October 2022

In this work, a rapid, highly selective, reusable and effective method was developed for simultaneous determination of alachlor, acetochlor and pretilachlor in field soil by GC-MS coupled with MIL-101 based SPE. Main factors affecting the SPE by using MIL-101 were optimized. Moreover, by comparing with the other commercial materials such as C18, PSA and Florisil, the MIL-101(Cr) exhibited excellent adsorption performance, which aimed at amide herbicides. On the other hand, method validation displayed excellent method performance, achieving good linearities with r2 ≥ 0.9921, limits of detection between 0.25–0.45 µg kg− 1, enrichment factors ≥ 89, matrix effect in the range of ± 20%, recoveries between 86.3% and 102.4%, and RSD lower than 4.38%. The developed method was successfully applied to the determination of amide herbicides in soil taken from the wheat, corn and soybean field at different depths, where the concentration of alachlor, acetochlor and pretilachlor were in the range of 0.62–8.04 µg kg− 1. It was demonstrated that the more depth of soil, the lower of three amide herbicides. This finding could be proposed a novel method to detect the amide herbicides in the agriculture and food industry.