bluuebunny/crossref_metadata_2025 huggingface dataset:
SYNTHESIS, STRUCTURAL CHARACTERIZATION AND SOLUBILITY INVESTIGATION OF FLURBIPROFEN ISOBUTANOL AMMONIUM SALT
Authors:   Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai-400 019, Maharashtra, India, Thakur Vaibhavi P. , Bagwe Pritam V. , Kharkara Prashant S. , Joshi Shreerang V.
Published: December 2023

This research is centered on the conversion of active pharmaceutical ingredients (APIs) into salt formulations, aiming to enhance their solubility, improve absorption into the bloodstream, and ultimately elevate their therapeutic effectiveness. More specifically, it delves into the synthesis and detailed characterization of flurbiprofen isobutanol ammonium salt. The confirmation of salt formation was achieved through a comprehensive analytical approach, including differential scanning calorimetry (DSC), thermogravimetry analysis (TGA), Fourier transform infrared (FTIR) spectroscopy, and powder X-ray diffraction (XRD). Notably, the successful formation of the isobutanol ammonium salt was verified by the discernible differences in DSC curves between the parent drug and the salt form. Powder XRD analysis further provided evidence of a chemical reaction occurring between flurbiprofen and 2-amino-2-methylpropan-1-ol, resulting in the creation of a distinct salt entity. Solubility studies unequivocally demonstrated that the conversion of flurbiprofen into its salt form significantly increased its solubility. Thus, the conversion of flurbiprofen into an isobutanol ammonium salt offers a viable solution to address the inherent solubility challenge associated with this BCS Class II API. This transformation has the potential to substantially enhance the bio-availability of flurbiprofen and improve its therapeutic effectiveness.
OMEGA-3 – ONLY VIRTUALLY BENEFICIAL FOR THE VEGANS & FANATIC VEGETARIANS!
Authors:   Consultant - NeuroMarketing & TechnoRegulatory (Pharma & Nutra)  Chairman – Nutraceutical Committee (IDMA)
Published: December 2023

Dear Reader, Dinner table conversations revolve around food, travel, politics and now, increasingly, health and nutrition – post the COVID-19 surge. Amongst the conditions commonly discussed, products for immunity, diabetes and heart disease take precedence. Besides immune builders, omega-3 (also referred to as n-3) has become the ‘talk of the town’ since it can benefit both the heart and also diabetes from which nearly 10% of urban Indians suffer.
An Improved Generative Adversarial Network with Feature Filtering for Imbalanced Data
Authors: Dou Jun , Song Yan
Published: December 2023

Article
An Improved Generative Adversarial Network with Feature Filtering for Imbalanced Data

Jun Dou 1, and Yan Song 2,*

1 Department of Systems Science, University of Shanghai for Science and Technology, Shanghai 200093, China
2 Department of Control Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
* Correspondence: sonya@usst.edu.cn;Tel.:+86-21-55271299; fax:+86-21-55271299
 
 
Received: 7 October 2023
Accepted: 31 October 2023
Published: 21 December 2023
 

Abstract: Generative adversarial network (GAN) is an overwhelming yet promising method to address the data imbalance problem. However, most existing GANs that are usually inspired by computer vision techniques have not yet taken the significance and redundancy of features into consideration delicately, probably producing rough samples with overlapping and incorrectness. To address this problem, a novel GAN called improved GAN with feature filtering (IGAN-FF) is proposed, which establishes a new loss function for the model training by replacing the traditional Euclidean distance with the Mahalanobis distance and taking the ℓ1,2-norm regularization term into consideration. The remarkable merits of the proposed IGAN-FF can be highlighted as follows: 1) the utilization of the Mahalanobis distance can make a fair evaluation of different attributes without neglecting any trivial/small-scale but significant ones. In addition, it can mitigate the disturbance caused by the correlation between features; 2) the embedding of ℓ1,2-norm regularization term into the loss function contributes greatly to the feature filtering by guaranteeing the data sparsity as well as helps reduce risk of overfitting. Finally, empirical experiments on 16 well-known imbalanced datasets demonstrate that our proposed IGAN-FF performs better at most evaluation metrics than the other 11 state-of-the-art methods.
Analisis Dampak Pendapatan Perkapita Terhadap Investasi Di Kota Jambi: Peran Inflasi Sebagai Variabel Mediasi
Authors: Putra Adi , Veronica Deka , Arniwita Arniwita , Daniel Prima Audia
Published: December 2023

Penelitian ini bertujuan mengetahui bagaimana pengaruh pendapatan perkapita terhadap  investasi dalam negeri di Kota Jambi. mengetahui bagaimana pengaruh pendapatan perkapita terhadap Inflasi di Kota Jambi serta untuk mengetahui bagaimana pengaruh pendapatan perkapita terhadap investasi dalam negeri melalui Inflasi di Kota Jambi. Penelitian ini menggunakan pendekatan penelitian deskriptif dan kuantitatif dimana data penelitan adalah data sekunder berbentuk runtut waktu (time series) periode tahun 2013-2022, berupa data pendapatan perkap ita, data inflasi dan investasi dalam negeri di Kota Jambi yang diperoleh dari Badan Pusat Statistik (BPS), Bank Indonesia (BI) serta sumber data pendukung lainnya. Selanjutnya data yang terkumpul tersebut dianalisis secara deskriptif menggunakan analisis perkembangan serta analisis secara kuantitatif menggunakan analisis Jalur (Path Analisys) dengan tujuan untuk menaksir pengaruh langsung (direct effect) antar variabel, sedangkan analisis pengaruh tidak langsung (indirect effect) untuk megetahui adanya pengaruh mediasi dengan menggunakan Uji Sobel (sobel test). Hasil penelitian di dapatkan dimana pendapatan perkapita tidak berpengaruh langsung secara signifikan terhadap investasi dalam negeri di Kota Jambi dan terhadap inflasi di Kota Jambi. Pengaruh mediasi inflasi terhadap pendapatan perkapita terhadap investasi dalam negeri di Kota Jambi juga tidak signifikan dimana nilai One-tailed probability yang didapatkan sebesar 0,121 dan nilai Two-tailed probability sebesar 0,242 yang lebih besar dari 0,05 menyatakan dimana pendapatan perkapita tidak berpengaruh terhadap investasi dalam negeri dengan mediasi inflasi, artinya variabel inflasi tidak tepat di pakai sebagai variabel mediasi antara pengaruh pendapatan perkapita terhadap investasi dalam negeri di Kota Jambi periode tahun 2013-2022.
Dampak Dana Perimbangan Terhadap Ekonomi Daerah Kabupaten/Kota di Provinsi Jambi
Authors: Yuvanda Sesraria , Rasjid Muhammad Rachmad , Herlin Faradilla
Published: December 2023

Penelitian bertujuan untuk menganalisis dampak DAU, DAK dan DBH terhadap Ekonomi daerah kabupaten/kota di Provinsi Jambi. Data yang digunakan merupakan data sekunder yang merupakan data panel yaitu gabungan antara jenis data time series 2017 – 2022 dan data silang (cross section) dari 11 kabupaten/kota di provinsi Jambi. Model Analisis pada penelitian ini menggunakan regresi data penel dengan dengan menggunakan alat E-Views 8.. Hasil penelitian menunjukan bahwa model yang tepat untuk penelitian ini adalah  Model Fixed Effect dengan memperlihatkan bahwa variable DAU berpengaruh positip terhadap PDRB, DAK berpengaruh negative terhadap PDRB sedangkan DBH tidak berpengaruh terhadap PDRB.
Pertumbuhan Ekonomi dan Ketimpangan Sosial: Tinjauan Terhadap Kebijakan Pembangunan di Indonesia
Authors: Edison Edison , Andriansyah Muhammad
Published: December 2023

Pembangunan ekonomi yang inklusif menjadi fokus utama dalam upaya mencapai kesetaraan akses dan kesempatan di Indonesia. Diskusi ini menguraikan beberapa aspek kunci dalam menciptakan fondasi pembangunan yang merata. Kebijakan fiskal yang inklusif menonjol sebagai landasan yang memastikan alokasi dana yang adil, keadilan pajak, dan investasi dalam program-program sosial serta infrastruktur yang merata. Investasi dalam pendidikan yang berkualitas dan merata menjadi landasan vital dalam menciptakan kesempatan yang setara bagi semua individu, mengurangi ketimpangan sosial, dan mendukung pertumbuhan ekonomi yang berkelanjutan. Pengembangan ekonomi daerah, terutama melalui pemberdayaan UMKM dan pembangunan infrastruktur, menjadi strategi penting dalam mengatasi kesenjangan antara wilayah perkotaan dan pedesaan. Namun, kolaborasi erat antara pemerintah, sektor swasta, dan masyarakat sipil menjadi esensi dalam merancang kebijakan dan program-program yang mendukung pembangunan inklusif. Melalui pendekatan terpadu dalam kebijakan, pendidikan, pengembangan ekonomi daerah, dan kemitraan antar-sektor, Indonesia dapat menuju arah yang lebih merata dalam pembangunan ekonomi, menciptakan kesetaraan akses, dan membangun masa depan yang inklusif dan berkelanjutan bagi seluruh masyarakatnya
1918’den Günümüze İşgal Korkusu ve Göçmen Sorunu Bağlamında Asya-Pasifik Bölgesi’nde Avustralya Dış Politikası
Authors: Özcan Orhan
Published: December 2023

Avustralya’nın jeostratejik olarak savunulması zor ve risk değerlendirmesi yüksek bir ada/kıta olmasının yanı sıra Anglo-Kelt kökenli bir etnik homojenliğe sahip olması, Avustralya’yı bölgesinde özel bir konuma yerleştirmiştir. 1850-1939 yılları arasında Asya-Pasifik’te Avustralya dış politiğini, Avustralya’da Çinli göçmen sorunu, Japon (yellow peril) ve Alman işgali risk değerlendirmesi merkezinde biçimlendirmiştir. Asya-Pasifik bölgesinde Avustralya, 1970’lere kadar kendisini Batı’ya ait hissetme ve Asyalı toplumları ötekileştirme üzerine kurgulanmış bir dış politika geliştirmiştir. Büyük Britanya’nın Avustralya’yla tarihi ve kültürel bağlarının güçlü olmasının ortaya çıkardığı bu tarihsel süreç, İkinci Dünya Savaşı’na kadar Büyük Britanya’nın Avustralya üzerinde siyasi, ekonomik ve askerî olarak baskın etkisine neden olmuştur. Bu bağlamda İkinci Dünya Savaşı’nın sonuna kadar Avustralya, Büyük Britanya’nın Asya-Pasifik’te ‘izole ileri karakolu’ olarak kalmasına neden olmuş ve savaş sonrası güç dengelerinin değişmesiyle Avustralya, ABD’nin koruma şemsiyesi altına girmiştir. Bu nedenle Soğuk Savaş sürecinde Avustralya, Asya-Pasifik’te ‘kızıl tehlike’ye karşı ABD’nin güdümünde göreceli bir dış politika üretmiştir. Asya-Pasifik bölge devletlerinin 1970’lerden sonra iktisadi bir güç olarak ortaya çıkması, Avustralya’da hızla yakın bölgesiyle bütünleşme eğilimi gösteren bir dış siyaset dönüşümü yaşanmasına neden olurken Avustralya’nın kendi kararlarıyla dış siyaseti belirleme yeteneği, işlevsellik kazanmıştır.
Ülkelerin Savunma Tedarik Zincirinde Görev Alan Devlet Bünyesindeki Organizasyon Yapılarının Karşılaştırmalı Değerlendirmesi ve Türkiye İçin Organizasyon Modeli Önerisi
Authors: Çelik Vasfiye , Erol Serpil
Published: December 2023

Savunma sanayii sektörü, ülkelerin güvenliği ve bekası ile doğrudan ilişkili olduğundan diğer sektörlere göre içerisinde farklı dinamikleri bulunmaktadır. Savunma sektöründe görev yapan kurum ve kuruluşların tedarik zincirleri, ülkelerin savunmaya yönelik stratejileri doğrultusunda ve her ülkenin kendine özgü yapısı ile harmanlanıp yönetilmesi ve oluşturulması gereken yapılar olmalıdır. Savunma tedarikinde görev alan kamu kurum ve kuruluşlarında tedarik zincirinin işletilmesinde ortaya çıkacak aksaklık ve problemler sadece maliyet artışı olarak karşımıza çıkmamakta, ülkenin güvenliğine yönelik önemli zafiyetlere de sebebiyet verebilmektedir. Çalışmada; dünyada savunma harcamaları en yüksek 10 ülkenin, savunma tedarik zincirinin kesintisiz bir şekilde yürütülmesini ve Silahlı Kuvvetlerin barış ve harekât zamanlarında ihtiyacının; zamanında, istenilen kalitede, miktarda, teknolojik seviyede, öngörülen maliyette karşılanması ile görevli ve devlet bütçelerinden bu doğrultuda önemli kaynaklar ayrılan kamu kurum ve kuruluşlarının organizasyonel yapılanmaları karşılaştırmalı olarak incelenmiştir. Bu yapıların organizasyon yapıları ve yıllar içerisindeki gelişimleri dikkate alınarak Türkiye’nin savunma tedarik ve lojistik sisteminde görev alan organizasyon yapılarına ışık tutularak Türkiye için yeni bir organizasyon modeli önerisinde bulunulmuştur.
Liman Von Sanders’in Almanca Raporlarına Göre Osmanlı Ordusunun I. Dünya Savaşı’nda Aldığı Yenilgiler Üzerine Bir Değerlendirme
Authors: Tuna Ozan
Published: December 2023

Yapılan çalışmalarda Osmanlı Devleti’nin Birinci Dünya Savaşı’nda Alman askeri misyonunun yanlış planlama ve uygulamalarının savaşta alınan yenilgilerde önemli ölçüde payı olduğu dile getirilmektedir. Ön plana çıkan en önemli figür ise Alman askeri misyon şefi Liman von Sanders olmakla birlikte kendisinin savaş esnasında Birinci Ordu Komutanlığı, Beşinci Ordu Komutanlığı ve Yıldırım Orduları Grup Komutanlığı gibi önemli mevkilerde görev alması da savaşta alınan yenilgilerde dahilinin olduğu kanaatini desteklemektedir. Alman Askeri Arşivi ve Alman Dışişleri Bakanlığı Arşivi’nde Liman von Sanders tarafından kaleme alınan raporlar incelenmiş ve kendisinin özellikle savaşta alınan yenilgilerde doğrudan dahilinin olmadığı argümanı vurgulanmıştır. Kendisinin raporlarında Osmanlı Devleti’nin Birinci Dünya Savaşı’nda askeri yenilgilerinde taktiksel hatalardan ziyade stratejik ve daha genel hatalar ortaya çıkartılmıştır. Bu bağlamda çalışmadaki amacımız Liman von Sanders tarafından düzenlenen Almanca raporlar üzerinden Osmanlı Devleti’nin Birinci Dünya Savaşı’ndaki askeri yenilgileri üzerine yeni bir bakış açısı getirmek şeklinde olmuş olup Almanca raporlar ve Türkçe referans eserler üzerinden çalışmamız icra edilmiştir.
Digital Misogyny Unveiled: An Examination of Online Hate Speech Targeting Women in Bangladesh
Authors:   Associate Professor, Department of Political Science, University of Dhaka, Dhaka-1000, Bangladesh., Yasmin Fatema Samina
Published: December 2023

Discriminatory and sexist language expresses bias towards men and projects that women are inferior around the world. It is also evident in the patriarchal society of Bangladesh. While they are often prevalent subtly in communication taking place in person, the anonymous nature of the internet has enabled people to be vile towards women in the virtual world. Online hate speech and misogynistic behavior have become pervasive issues in today's digital landscape. Most people take Islamic verses literally or believe the religious clerics without checking their words' authenticity. The socio-religious idea of women being subservient to men produces numerous hate speeches against women on social media platforms. The presence of numerous online religious lectures spewing offensive words against women made the situation worse in Bangladesh. They conform to the prevalent idea that men should control women's agency, and for that purpose, even violence is acceptable. This article aims to provide a comprehensive analysis of the phenomenon, specifically focusing on the context of Bangladesh. Through case studies, it looks into how religious leaders fuel online hatred towards women.It further explores the various forms, impacts, and underlying factors of misogynistic online speech. By delving into the complexities of this issue, it also discusses the challenges faced by women in seeking redress and proposes recommendations to mitigate online violence against women in Bangladesh.
Improvement of Bituminous Pavement by Adding Waste Plastic
Authors:   Department of Civil Engineering, Technocrats Institute of Technology Bhopal (M.P), India., Khan Dr. Md. Imran
Published: December 2023

The present paper reports the results of a study undertaken to determine the physical properties of aggregates, 80/100 grade bitumen, optimum bitumen content by using Marshall mix design, optimum plastic content and also to compare the results with plain mix. Keywords: Bitumen, Concrete, Aggregates, Cement, Sand Etc.
EFFICACY OF UTERINE PACKING AND INTRAUTERINE BALLOON TAMPONADE IN ATONIC POSTPARTUM HEMORRHAGE COMPARISON
Authors: KHAN N , ALI K
Published: December 2023

A randomized controlled trial was conducted between March 1, 2023, and September 1, 2023, at the Gynae unit of the Mardan Hospital complex in Mardan. The study aimed to evaluate the effectiveness of two strategies in treating postpartum hemorrhage caused by atony. The two strategies evaluated were uterine gauze packing and uterine balloon tamponade. A total of 168 women who had experienced postpartum hemorrhage due to uterine atony after a vaginal birth were enrolled in the study through non-probability sampling. Patients with clotting disorders, trauma-related hemorrhage, and those who had undergone cesarean deliveries were excluded from the study. The study had two groups of patients, with 84 patients enrolled in group A and 84 in group B. The study aimed to compare the effectiveness of the two strategies in minimizing blood loss in the first 24 hours following birth. The study found that uterine balloon tamponade was more effective in reducing postpartum hemorrhage caused by uterine atony than uterine gauze packing. Specifically, 75 (89.3%) patients in group A reported the effectiveness of uterine balloon tamponade, while uterine gauze packing was reported in 61 (72.6%) patients in group B. This difference in effectiveness was statistically significant (P=0.006). The Chi-square test was used to compare the two groups, with a P value of 0.05 considered significant. In conclusion, the study suggests that uterine balloon tamponade is more effective in reducing postpartum hemorrhage caused by uterine atony than uterine gauze packing.
Endoscopic intermuscular dissection for locally advanced rectal cancer: A case report
Authors: Sekra Anurag , Tan Tracy
Published: December 2023

BACKGROUND

Endoscopic submucosal dissection is considered curative for patients with early rectal cancer when level of submucosal invasion is < 1000 microns with favourable histopathological features. Recent data suggests even deeper submucosal invasion can potentially be curative if R0 resection can be achieved and when no high-risk histopathological features are seen in the resected specimen. To achieve R0 resection, deeper dissection is required.

CASE SUMMARY

A 66 year old New Zealand European male presented with 3 mo history of per rectal bleeding. He was referred for a colonoscopy test to investigate this further. This revealed a malignant appearing lesion in the rectum. Biopsies however showed high grade dysplasia only. Given endoscopic appearances suspicious for deep submucosal invasion, patient was consented for endoscopic intermuscular dissection (EID). The case was successfully performed, and the presence of muscularis propria was confirmed in the resected specimen. There were no complications and total procedure time was 124 min. Lesion was clear of radial margins however deep margins were positive confirming it was at least a pT2 cancer. Patient was recommended to have further treatment but could not have radical surgery due to comorbidities and instead was referred for long course chemoradiotherapy.

CONCLUSION

EID is a safe and feasible option for management of rectal cancer in highly selected patients.
Predictive Modeling Through Fusion of Passengers Information Transferred to Alternate Dimensions
Authors:   Universidad Regional Autónoma de los Andes (UNIANDES), Ecuador, Torres Fabricio Lozada , Gómez Sharon Álvarez ,   Universidad Regional Autónoma de los Andes (UNIANDES), Ecuador, Rivero Diego Palma ,   Universidad Regional Autónoma de los Andes (UNIANDES), Ecuador, Odar Christian F. Tantaleán ,   Universidad Nacional Mayor de San Marcos, Peru, Shukhrat Sayfuddinov ,   TSUE Marketing department, Uzbekistan
Published: December 2023

This research focuses on the identification of passengers, in dimensions using information fusion as a tool. We recognize the challenges involved in identifying individuals who have been transferred to alternate dimensions and in this study we make use of CatBoost, an open source machine learning algorithm to address this problem. Our approach includes a preprocessing strategy that involves filling in missing values using techniques like priori distribution terms, which helps ensure the reliability of our dataset. By leveraging CatBoosts ability to handle variables and prevent overfitting we achieve results in accurately predicting passenger movement across dimensions. Our analysis highlights CatBoosts effectiveness in identifying patterns within data leading to more precise predictions for interdimensional passenger transportation. Additionally we incorporate techniques, like Greedy TS augmentation to enhance the adaptability of the algorithm and improve precision while reducing bias in modeling. Proof-of-concept experiments demonstrate that the proposed fusion system not only advances predictive modeling in niche domains but also paves the way for broader applications of machine learning in deciphering complex phenomena beyond traditional realms, marking a significant stride in understanding and addressing unconventional challenges.
Survival Analysis Based on Fusion of Decisions from Multiple Tree Structure: A Cutting-Edge Approach
Authors:   Universidad Regional Autónoma de los Andes (UNIANDES), Ecuador, Paz Luz M. Aguirre ,   Universidad Regional Autónoma de los Andes (UNIANDES), Ecuador,   Universidad Regional Autónoma de los Andes (UNIANDES), Ecuador,   Club  deportivo de la universidad San Martín de Porres, Peru,   TSUE Research department, Uzbekistan, Moya Jorge Viteri , Vásquez Rita Azucena D. V� , Guerra Darvin M. Ramírez , Burkhon Dekhkonov
Published: December 2023

Survival analysis remains an important area in predictive modeling, especially in cases where event timing information is critical. This work presents a research effort to investigate the application of LightGBM, a high-performance high-throughput model, to conduct an improved fusion of decisions from multiple trees to reach survival analysis. Our objective is to address the challenge of developing correct predictive models while advancing computational effectiveness. Based on a case study of live disaster scenarios, the proposed approach applies and compares LightGBM with traditional prediction methods, which involve careful design engineering, and model training with LightGBM tree structure refinement. The results obtained from fair experimentation and comprehensive predictive performance evaluation demonstrate the robustness of LightGBM in increasing the accuracy of relevant classification tasks toward survival analysis. Furthermore, the findings highlighted that the combination of excellent tree depth for cutting and multi-thread optimization promotes efficient computational complexity and prediction accuracy.
An Information Fusion Technique for Prognosticating Future Air Passenger Trends
Authors:   Universidad Regional Autónoma de los Andes (UNIANDES), Ecuador, Zambrano Luis A. ,   Universidad Regional Autónoma de los Andes (UNIANDES), Ecuador,   Universidad Regional Autónoma de los Andes (UNIANDES), Ecuador,   International Center for Entrepreneurs in Barcelona (ICEB), Spain,   TSUE Research department, Uzbekistan, Ocaña Luis llerena Oca� , Morales Tannia Cristina P. , Falcón Vladimir Vega Falc� , Sanjar Mirzaliev
Published: December 2023

The aviation industry is constantly changing and to keep up with the trends of air passengers we need predictive models. In this paper, we explore the use of Information Fusion methodologies and classical time series techniques to forecast how many passengers will be traveling by air. Predicting passenger demands is a task, due to various factors that influence travel patterns. The existing models often struggle to capture the dynamics in this field so it's crucial to develop accurate forecasting methods. By leveraging information fusion techniques like smoothing and Autoregressive Integrated Moving Average (ARIMA) our research creates models based on historical data of air passenger volumes. These techniques combine machine learning algorithms and time series analysis to identify dependencies and patterns in the dataset. Through evaluations and comparative analyses, our proposed models demonstrate promising capabilities in forecasting future air passenger volumes. Proof-of-concept experiments based on 5-fold cross-validation demonstrate the efficacy of the proposed approach in capturing underlying trends and seasonality within the dataset.
On n-Refined Neutrosophic Vector Spaces For Some Special Values 3≤ n ≤6
Authors:   College Of Pharmacy, AL-Farahidi University, Baghdad, Iraq, Salman Nabil Khuder ,   Universidad Regional Autónoma de los Andes (UNIANDES), Ecuador,   Universidad Regional Autónoma de los Andes (UNIANDES), Ecuador, Jadan Bolívar Villalta , Flores Marcos Lalama
Published: December 2023

This work is dedicated to study some different types of n-refined neutrosophic vector spaces for different values of n between 3 and 6. Where we present some related algebraic concepts such as 3-refined neutrosophic homomorphism, 4-refined neutrosophic homomorphism, 5-refined neutrosophic homomorphism, and 6-refined neutrosophic homomorphism. Also, we provide some theorems to clarify the algebraic behaviour of 3-refined, 4-refined, 5-refined, and 6-refined neutrosophic subspaces.
On The Classification of 3-Cyclic/4-Cyclic Refined Neutrosophic Real and Rational Von Shtawzen's Group
Authors:   AL-Farahidi University, Baghdad, Iraq, Salman Nabil Khuder ,   Universidad Regional Autónoma de los Andes Sede Babahoyo (UNIANDES Babahoyo). Ecuador,   Universidad Regional Autónoma de los Andes (UNIANDES Babahoyo), Ecuador, Vazquez Maikel Leyva , Noel Batista Hernández
Published: December 2023

This paper aims to solve the group of units problem for 3-cyclic real and rational refined neutrosophic rings and 4-cyclic real and rational refined neutrosophic rings, where ring isomorphisms between the realrational 3-cyclic and 4-cyclic refined neutrosophic rings and the direct product of some field extensions of Q and R. These isomorphisms will help in classifying the group of units of each studied ring in terms of direct products of classical well-known abelian groups. Also, we use the classification isomorphisms to determine all ideals in these classes of algebraic rings.
Lo que insiste, lo que cambia, lo que emerge en el quehacer en Psicología Comunitaria: Los casos de Argentina, México y Uruguay
Authors: Lenta María Malena , Castillo Teresita , Pierri Lucía , Rigueiral Gustavo Javier , Rodríguez Ferreyra Alicia Raquel
Published: December 2023

xxxEl artículo presenta reflexiones emergentes de tres procesos de investigación desarrollados en Argentina, Uruguay y México que estudian las prácticas en comunidad de profesionales de la psicología. Se busca elucidar la praxis de la psicología comunitaria en la actualidad, con una perspectiva historizante, tomando como ejes de análisis los campos de problemas, los dispositivos de intervención, los posicionamientos identitarios, el vínculo con las políticas sociales y las concepciones sobre la transformación social. Desde una perspectiva situada y un enfoque cualitativo, se conformó un diseño de estudio de casos múltiples, donde cada país constituye un caso. Se desarrollaron grupos de discusión y entrevistas en profundidad que pasaron por un proceso de análisis de contenido que permitió la comparación entre los casos. Entre los principales hallazgos destaca que el quehacer comunitario se homologa al trabajo territorial en el que toma un sentido polisémico, y reconoce tensiones, conflictos y posibilidades. La complejidad de las problemáticas abordadas interpela las fronteras e identidades profesionales, convocando a la transdisciplina. Finalmente, los alcances de la transformación social producto de las prácticas son interpelados en diferentes grados desde la relación con el Estado, las políticas públicas, las ONGs y los movimientos sociales con los que trabajan.
¿Coexistir o no coexistir? Ese es el dilema a resolver para una vida personal y planetaria más saludable y feliz
Authors: Alarcón Carvacho Patricio
Published: December 2023

La inexistencia, la desconexión, las relaciones vacías, la incomunicación carente de empatía y asertividad, la soledad, la violencia, el pseudoamor enferman y generan una pseudofelicidad construida con los intereses del mercado y sobre los principios y el poder de la economía neoliberal, que coloniza y mercantiliza según sus estándares y homogenizaciones al ser, al existir y al coexistir. Recuperar la salud y la felicidad personal y planetaria requiere con urgencia del coexistir, de una nueva coreografía de las pautas que conectan con el coexistir pleno y amoroso, sustentándola en la recursividad de una comunicación nutritiva, afectiva-efectiva, compasiva y validadora absoluta e integral de los otros(as) y lo otro.
Adaptación y validación del Inventario de Compromiso con la Clase en estudiantes secundarios y universitarios de Argentina, Bolivia y Chile
Authors: Leal-Soto Francisco , Cuadros Jiménez Olga , Ferrer-Urbina Rodrigo , Dávila Juan
Published: December 2023

xxEl compromiso con la clase ha cobrado gran relevancia, ya que permite visualizar el grado en que los estudiantes están involucrados con las actividades dentro del aula, producto de su motivación por aprender. Pese a ello, este constructo se ha investigado menos que otro similar pero menos específico, el compromiso escolar. Asimismo, conviene explorar sus alcances en estudiantes universitarios. El presente trabajo busca responder a estos desafíos. Concordantemente, el objetivo consiste en adaptar y validar el Classrroom Engagement Inventory (CEI, Inventario de Compromiso con la Clase) en estudiantes latinoamericanos de secundaria y educación superior. Se tradujo al español y adaptó el Classrroom Engagement Inventory, que mide cinco dimensiones de compromiso con la clase. El instrumento fue administrado a 446 estudiantes secundarios chilenos y 747 universitarios en Argentina, Bolivia y Chile (estudio 1) y, junto a otros dos instrumentos, a 130 estudiantes secundarios chilenos, para establecer evidencia de validez basada en la relación con otras variables (estudio 2). El estudio 1 implicó análisis de fiabilidad, análisis factorial confirmatorio y análisis multigrupo; el estudio 2, correlación y regresión sobre compromiso. Los resultados confirmaron la estructura de cinco factores correlacionados (compromiso afectivo, compromiso compelido, compromiso activo, compromiso cognitivo y desconexión), su invarianza entre niveles educativos y nacionalidad, y la capacidad predictiva de autoestima colectiva y atribución de causalidad sobre compromiso con la clase. Se concluye que el instrumento resulta apropiado para su uso en estudiantes latinoamericanos, tanto de secundaria como de educación superior.
¿Una “base” en la Antártica para la identidad social? Conceptualización de una identidad social Antártica
Authors: Estrada Goic Claudia , Cárdenas José Manuel , Gallardo Ismael , Barrientos Jaime
Published: December 2023

Este artículo revisa las propuestas conceptuales actuales que abordan la relación entre las personas y los espacios geográficos. Las propuestas desde la psicología ambiental tales como la identidad de lugar y el de apego al lugar resultan insuficientes para dar cuenta del fenómeno de identificación con territorios con los que no se interactúa directamente. Poniendo como ejemplo de análisis a habitantes de una puerta entrada a la Antártica, se reflexiona en torno a los potenciales aportes de la psicología geográfica y social clásica. Se propone el concepto de Identidad Social Antártica como una noción que reúne aspectos centrales de la identificación social cuando ocurre a partir de una relación simbólica con un territorio que se siente propio. La consideración de esta alternativa para explicar los vínculos identitarios con imaginarios geográficos podría extrapolarse a otros espacios terrestres en los que la experiencia directa con los entornos ambientales no es habitual.
Databases on aromatic plants
Authors:   Professor. University of Sucre. Medical and Pharmaceutical Sciences group. Sincelejo, Sucre, Colombia, Pájaro Castro Nerlis
Published: December 2023

Essential oils are a mixture of isoprenoid-type organic compounds that have many biological properties and have been widely used in the cosmetic, food, and pharmaceutical industries, among others. That is why there is a lot of information on this broad group of molecules, in fact, there are specialized databases with detailed information on different essential oils from different types of plants. This review aimed to search the existing databases with information on essential oils. The search of the databases was carried out using the keywords databases and essential oils in different search engines. This yielded a variety of specialized databases with detailed information on essential oils and their sources of obtaining them, as well as chemical structures, physicochemical properties, forms of extraction, pharmacological and biological properties, and utility, among others. In conclusion, these essential oil databases have advantages such as the potential to discover new medicines from nature and gather important information for users so that they can easily browse, search, download, and view data on a natural product of interest.
Caracterización de un enjuague bucal mucoadhesivo con nanopartículas de plata
Authors:   Unidad de Formulación, Caracterización y Optimización. Instituto de Investigaciones Farmacéuticas. Facultad de Farmacia. Universidad Central de Venezuela, Caracas, Andueza Isabel
Published: December 2023

En el presente trabajo se caracterizaron las propiedades físicas de un enjuague bucal mucoadhesivo desarrollado con nanopartículas de plata (NpsAg). Para mantener concentraciones efectivas de los ingredientes activos por períodos prolongados en la cavidad oral, es fundamental que las formulaciones resistan la temperatura, el recambio salival y los movimientos bucolinguales. Es por lo que la asociación de polímeros mucoadhesivos con sistemas nanopartículados es una alternativa que mejoraría la efectividad terapéutica y modificaría el patrón de liberación, favoreciendo la penetración de los ingredientes activos en la biopelícula dental; reduciendo la placa, gingivitis y halitosis, entre otras patologías. Se elaboraron tres lotes y se evaluaron las propiedades organolépticas (color, olor, sabor y apariencia). Se determinaron por triplicado a 26°C, la viscosidad (η) en un viscosímetro rotacional LVT, con aguja L1 a 12 r.p.m. A una disolución al 2% p/p en agua destilada se le midió el pH y la conductividad en un pHmetro/ISE Thermo Electron Scientific, modelo Orion 4-Star. El enjuague presentó un color gris claro, sabor dulce-refrescante de apariencia ligeramente viscosa. Se reportaron valores de viscosidades dentro del rango entre 100-150 mPa.seg, con un pH dentro el rango fisiológico. La conductividad se encontró en un rango entre 140-160 μS/cm, no evidenciando diferencia significativa durante el mes de estudio. La combinación de los componentes empleados en el desarrollo de este enjuague bucal podría ser una nueva alternativa más eficiente en los efectos: antiinflamatorio, antioxidante y antimicrobiano. Igualmente, protegería por más tiempo el ambiente bucal contra la aparición de enfermedades periodontales.
El envejecimiento: ¿Podemos frenarlo? Autofagia/Nutrición. Reprogramación Celular Segunda Parte
Authors:   Prof. Jubilado, Universidad Central de Venezuela, Facultad de Farmacia, Cátedra de Biología, Garrido María del Rosario
Published: December 2023

Como individuos, estamos sujetos a daños permanentes en las células y los tejidos. Muchos factores contribuyen a esto, entre ellos, el deterioro propio de la madurez y el envejecimiento. La autofagia es un proceso de reciclaje presente en todas las células que permite la degradación dentro de los lisosomas de componentes celulares dañados o prescindibles. Ocurre naturalmente preservando a las células de la acumulación de toxinas, moléculas y organelos dañados y además permite los procesos de desarrollo y diferenciación de los tejidos. Los sustratos reciclados generan ATP, lo que constituye una fuente alternativa de energía en situaciones de estrés. Alteraciones en el funcionamiento de la autofagia pueden desarrollar diversas patologías, tales como el daño hepático, el cáncer y las enfermedades neurodegenerativas. A medida que envejecemos experimentamos un incremento de las enfermedades. Se ha demostrado el papel relevante de la genética gracias a la caracterización de muchos “loci” que influyen en los rasgos de envejecimiento, surgiendo varias estrategias para atenuar los efectos fisiológicos del mismo. En este contexto, la reprogramación celular mediada por el uso de factores de pluripotenciales ha demostrado ser capaz de revertir el fenotipo celular envejecido. Más aún, los protocolos de rejuvenecimiento por reprogramación parcial han logrado revertir la edad biológica, medible por biomarcadores de gran precisión conocidos como relojes epigenéticos.
El Polipéptido Insulinotrópico dependiente de Glucosa en la Preeclampsia y el Riesgo de Diabetes Gestacional
Authors:   Laboratorio de Neuropéptidos, Facultad de Farmacia, Universidad Central de Venezuela, Camacho Elsa
Published: December 2023

La preeclampsia (PE) es un síndrome exclusivo de la gestación humana cuyas manifestaciones incluyen la hipertensión arterial, proteinuria y edema. Su incidencia incrementa en mujeres con síndrome metabólico y resistencia a la insulina. El embarazo es un estado único caracterizado por resistencia a la insulina fisiológica que se resuelve después del parto. El polipéptido insulinotrópico dependiente de glucosa (GIP) es una hormona que se libera en el intestino delgado en respuesta a la ingesta de alimentos. Su principal función es regular la homeostasis de la glucosa en la sangre estimulando la secreción de insulina. Se conoce poco acerca del papel del GIP en la preeclampsia y la resistencia a la insulina gestacional. Se cuantificaron los niveles plasmáticos del GIP en mujeres con embarazo normal y con PE, pertenecientes a una población de 30 mujeres venezolanas. Se evaluaron muestras de plasma mediante el análisis multiplex de microesferas (Bio-Plex Pro Assays). Los resultados muestran incrementos significativos de los niveles plasmáticos del GIP, asociados a aumentos de insulina y resistina en las pacientes con preeclampsia comparados con las embarazadas sanas. La PAS y las variables evaluadas mostró una la correlación positiva, estadísticamente significativa, entre la PAS vs. proteinuria, glicemia, GIP, resistina e insulina. Los resultados sugieren que el incremento del GIP podría estar asociado al desarrollo de hipertensión y resistencia a la insulina en pacientes con PE. Igualmente, indican que el GIP y los parámetros evaluados pudrían constituir posibles biomarcadores para predecir la aparición de hipertensión inducida por el embarazo y la diabetes gestacional.
Risk Factors of Emergency Department Utilization After Outpatient Surgery for Sports-Related Injuries
Authors: Chen Mingda , Raji Yazdan , Sivasundaram Lakshmanan , Voos James E.
Published: December 2023

Introduction:

The purpose of this study was to identify the most common reasons for and risk factors associated with postoperative emergency department (ED) utilization after orthopaedic procedures for sports-related injuries.

Methods:

Using the 2014 to 2016 New York and Florida State Databases from the Healthcare Cost and Utilization Project, outpatient procedures for sports-related injuries were identified. Patient records were tracked across care settings within each state to determine the rate and reasons of postoperative ED utilization within 90 days after the index surgery. Multiple logistic regression models were used to identify risk factors associated with ED visits at 0 to 7 days, 8 to 30 days, 31 to 90 days postoperatively.

Results:

A total of 28,192 surgery visits for sports-related injuries were identified, with knee arthroscopy with partial meniscectomy (18.48%) and arthroscopic anterior cruciate ligament reconstruction (17.04%) as the two most common procedures treating sports injuries. The overall postoperative ED utilization rates were 1.6% (0 to 7 days postoperative), 1.3% (8 to 30 days) and 2.1% (31 to 90 days). The main cause of ED visits was markedly different during each postoperative period: mainly musculoskeletal pain (36.3%) during 0 to 7 days, either musculoskeletal pain (17%) or injury (16.6%) during 8 to 30 days, and injury (24.2%) during 31 to 90 days. Sports with the highest ED utilization in descending order were basketball, football, ice/snow sports, walking/running, cycling, and soccer. Relative to open procedures, arthroscopic procedures were 0.71 times as likely to result in a postoperative ED visit. Independent predictors of ED utilization up to 90 days postoperatively included renal failure, chronic pulmonary disease, psychosis, diabetes, and alcohol abuse.

Discussion:

Rate of ED utilization after outpatient surgery for sports-related injuries is low (<2.2%), with postoperative musculoskeletal pain and reinjury as the two most common causes, highlighting the importance of postoperative pain management and injury prevention. Arthroscopic procedures showed markedly lower ED utilization compared with open surgery, although not indicative of overall superiority.

Level of evidence:

III, Retrospective Cohort Study.
Management of Isolated Greater Trochanter Fractures Associated With Total Hip Arthroplasty
Authors: Fraval Andrew , Hegeman Erik M. , Krueger Chad A.
Published: December 2023

Periprosthetic hip fractures are recognized complications associated with total hip arthroplasty. Over the past decade, there has been a 2.5-fold increase in the incidence of periprosthetic fractures which is expected to grow exponentially in the future. Most of these fractures require surgical fixation or revision arthroplasty. Fractures of the greater trochanter represent a subset of periprosthetic fractures for which there is currently no consensus in the literature regarding the optimal management. The purpose of this review was to outline the management strategies available to address these fractures, with formulation of recommendations for fractures sustained intraoperatively, postoperatively, and in the setting of primary and revision total hip arthroplasty.
RESOURCES TO FACILITATE AND IMPROVE LEARNING PERFORMANCE
Authors: Setyadi Wahyu , Khabib Sulistiyo M , Ramaini Ramaini , Idarwanto Idarwanto , Atthoharoh Atthoharoh , Nuzli Muhammad
Published: December 2023

This study aims to describe: what are the appropriate resources in PAI learning, and how the role of teachers as resources in PAI learning at SMA Negeri 13 Merangin. Qualitative research method, data collection techniques of observation, interview, and documentation, and analyzing the data that has been obtained using data analysis, namely data reduction, data presentation, and data verification. The results obtained from this study are that the 11th grade PAI learning of SMA Negeri 13 Merangin uses resources in accordance with the material to be studied, as well as using supporting tools such as props and infokus to explain learning materials, and the PAI teacher of SMA Negeri 13 Merangin is also someone who is professional in his field. The conclusion obtained from the results of this study is that the educational technology resources in SMA Negeri 13 Merangin are good both in terms of resources of tools, materials, devices, people, and the learning environment has gone well.
HAYVAN REFAHI: DİN VE İNANÇ ÖZGÜRLÜĞÜNE GETİRİLEN YENİ BİR SINIRLANDIRMA NEDENİ Mİ?
Authors: HAZAR Zeynep
Published: December 2023

Felsefi ve bilimsel boyutlarıyla ele alınabilen hayvan refahı kavramı, 20. yüzyılın ikinci yarısından itibaren hem Avrupa Birliği hem Avrupa Konseyi nezdinde hukuki düzenlemelerin konusunu oluşturmaya başlamıştır. Hayvan refahına ilişkin AB düzenlemeleri; AB’ye üye devletlerin, hissedebilen varlıklar olarak kabul edilen hayvanların refahına azami ölçüde dikkat etmeleri gerektiğini belirlemiştir. Düzenlemeler aynı zamanda, AB’nin ve üye devletlerin dini ayinlere saygı gösterme zorunluluğunu içerir. Hayvan refahını koruma yükümlülüğü bağlamında, AB’ye üye devletler hayvan kesiminde öldürmeden önce bayıltma işlemini uygulamak zorundadır. AB müktesebatınca bir ilke olarak kabul edilen söz konusu işlem, Belçika’da yaşayan Musevi ve Müslümanların bir bölümü tarafından din ve inanç özgürlüğünün ihlali olarak değerlendirilmiştir. Bu durum din ve inanç özgürlüğü ile hayvan refahının karşı karşıya gelmesine neden olmuştur. Çalışmada ilk olarak, dini kurallara uygun hayvan kesiminin, din ve inanç özgürlüğünün kapsamına girip girmediği sorusuna cevap aranmıştır. Avrupa İnsan Hakları Mahkemesinin din ve inanç özgürlüğü çerçevesindeki içtihatları ve 2000 yılında vermiş olduğu Cha’are Shalom ve Tsedek v. Fransa kararı uyarınca, dini kurallara uygun hayvan kesimi uygulamaları, din ve inanç özgürlüğünün bir parçası olarak kabul edilmiştir. Çalışma kapsamında cevabı aranan ikinci soru ise hayvan refahının, dini kurallara uygun hayvan kesimi bağlamında din ve inanç özgürlüğünü sınırlandıran bir neden olup olmadığıdır. Avrupa Birliği Adalet Divanının 2020 yılında verdiği Belçika Merkez İsrail Konseyi ve Diğerleri kararı ile dini kurallara uygun hayvan kesimi, hayvanların refahının korunması amacı çerçevesinde tekrar tartışılmaya açılmıştır. ABAD mevzubahis kararda, çağdaş demokratik toplumlar için hayvan refahının son yıllarda yükselen bir değer olduğunu ifade etmiştir. ABAD’a göre hayvan refahı, toplumdaki değişimler ışığında, din ve inanç özgürlüğü bağlamında daha fazla dikkate alınmalıdır. ABAD’ın insan hakları metinlerinin dinamik doğasına yaptığı vurgu ve bir insan hakkı karşısında hayvan refahını dikkate alarak orantılılık incelemesi yapması, hayvanların menfaatlerinin yalnızca din ve inanç özgürlüğü bağlamında değil genel olarak insan haklarını sınırlandıran bir neden olarak ortaya çıkışının ayak sesleri olarak okunabilir.
Utilization of Disposable Diaper Waste with Added Naphthalene Formaldehyde Sulfonate into Paving Blocks in an Effort to Minimize Waste to Reduce Environmental Pollution
Authors: Juita Mayang Sari , Ardiatma Dodit , Ilyas Nur Ilman
Published: December 2023

This research aims to determine the best classification and composition of paving blocks mixed with baby diaper waste in terms of compressive strength and water absorption of paving blocks based on SNI 03-0691-1996, the effect of variations in baby diaper waste on compressive strength and water absorption tests and to determine the quality comparison. paving blocks mixed with baby diaper waste and commercial paving blocks. The method used in this research is an experimental method, using a quantitative approach. The materials used to produce paving blocks are cement, sand, water, a mixture of baby diaper waste and the added ingredient sikacim concrete additive. The samples were tested to determine the relationship between physical characteristics and mechanical properties with material composition in accordance with the quality of Paving Blocks produced based on SNI 03-0691-1996. In this research, it was determined based on the planning ratio between cement and sand, namely 3:7. Baby diaper waste added to the paving blocks was 0 grams, 5 grams, 10 grams, 15 grams and 20 grams. The best classification and composition for adding baby diaper waste to paving blocks if viewed from the compressive strength of paving blocks is by adding 10 grams of baby diaper waste with a compressive strength of 36.76 Mpa which meets the SNI 03-0691-1996 quality classification A, where this paving block can be used for roads, container terminal land pavement at ports, non-structural and structural needs with other heavy loads. Meanwhile, if we look at the water absorption capacity of the paving blocks, the best classification and composition of adding 5 grams of baby diaper waste with the lowest water absorption capacity of 1.41% meets the SNI 03-0691-1996 quality classification standard A.