bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of Chat GPT’s Impact on Education Using Deep Spectral-Spatial Residual Attention Networks
Authors: Ismail Walaa , Youssry Howida
Published: February 2025

The revolutionary influence of powerful generative models, such as Chat Generative Pre-trained Transformer (ChatGPT) and mid-journey is causing significant changes in the higher education setting. These models examine the future of education and its potential to completely transform the way to teach and learn and have far-reaching implications. In this paper, investigation of ChatGPT’s impact on education using Deep Spectral-Spatial Residual Attention Networks (DSSRAN-CGPT) is proposed. Initially, the input data is amassed from ChatGPT sentiment analysis dataset. The input data is pre-processed using Continuous-discrete Derivative-free Extended Kalman Filter (CDFEKF) to remove the unwanted data from the collected input data; then the pre-processed data are fed to feature extraction using Synchro-Transient-Extraction Transform (STET) to extract the statistical features, like energy, standard deviation, variance and kurtosis. Then the extracted features are supplied to the DSSRAN for effectively classifying the positive sentiment, negative sentiment and neutral sentiment. Generally, DSSRAN does not adapt any optimization approaches to determine the optimal parameters to ensure accurate classification of ChatGPT in education. Hence, Parrot Optimization Algorithm (POA) is proposed to optimize the DSSRAN, which accurately classifies the ChatGPT in education. The performance metrics, like accuracy, precision, recall, specificity, F1-score, computation time and Receiver Operating Characteristic curve (ROC) are analyzed. The performance of the proposed DSSRAN-CGPT approach attains 97% accuracy; 92% higher precision and 75% lower computation time when compared to the existing methods, like exploring the impact of ChatGPT in education: A web mining including machine learning approach (CGPT-ELA), unlocking the opportunities through ChatGPT Tool towards improving the education system (CGPT-AES) and ChatGPT in education: A discourse analysis of Worries and Concerns on Social-Media (CGPT-WCSM).
Kazakçada Moğolca Akrabalık Adları Üzerine Bir İnceleme
Authors: Oba Emin
Published: February 2025

One of the words that constitute the basic vocabulary of a language is kinship names. These words are among the words that are exchanged between languages with the interaction between cultures. In this study, kinship names borrowed from Mongolian in the vocabulary of Kazakh will be examined. While examining these words, the forms and meanings of the words in Middle Mongolian, Literary Mongolian and Modern Mongolian will be given. In addition, the forms and uses of the word in historical Turkic dialects and modern Turkic dialects will be given. In addition, the origin explanations related to the word will be included.
Wilkens, J. Uigurisches Wörterbuch, Sprachmaterial der vorislamischen türkischen Texte aus Zentralasien. III. Fremdelemente, Band 3: čihui – gwıšı. Stuttgart: Franz Steiner Verlag, 2025, pp. XXVI+181, ISBN: 978-3-515-13888-8.
Authors: Uçar Erdem
Published: February 2025

Wilkens, J. Uigurisches Wörterbuch, Sprachmaterial der vorislamischen türkischen Texte aus Zentralasien. III. Fremdelemente, Band 3: čihui – gwıšı. Stuttgart: Franz Steiner Verlag, 2025.
Baranoğlu, Ş. Kutadgu Bilig’de Söz Dizimi. Ankara: Sonçağ Akademi Yayınları, 2024, ss. 181. ISBN: 978-625-6074-48-4.
Authors: Egemen İlayda
Published: February 2025

Baranoğlu, Ş. Kutadgu Bilig’de Söz Dizimi. Ankara: Sonçağ Akademi Yayınları, 2024.
Potenziale von Praxisforschung durch die Vernetzung und Kooperation zweier Lernwerkstätten. Das Kinderforscher*zentrum HELLEUM und die Hochschullernwerkstatt Kommunikation und Sprache der Alice Salomon Hochschule Berlin
Authors: Theisselmann Olga , Hruška Claudia A. , Schmude Corinna
Published: February 2025

Das Kinderforscher*zentrum HELLEUM als etablierte außerschulische Lernwerkstatt, die historisch an die Alice Salomon Hochschule Berlin (ASH Berlin) angebunden ist, zeigt sich durch ein facettenreiches Programm für Kinder sowie angehende und praktizierende Lehrkräfte und pädagogische Fachkräfte. Es entwickelt sich aktuell zum Professionalisierungsort, an dem die forschende pädagogische Haltung, die Grundbasis für die Ermöglichung des Forschenden Lernens der Kinder, geübt und gelebt wird. Der gewählte Ansatz hierfür ist insbesondere die Praxisforschung, die einen wichtigen Beitrag zur Qualitätssicherung und Weiterentwicklung der Bildungseinrichtungen leisten kann. Diese bedarf wissenschaftlicher Unterstützung, die durch die Kooperation zwischen dem HELLEUM und der Hochschullernwerkstätten der ASH Berlin ermöglicht wird. In diesem Beitrag wird es am Beispiel eines Kooperationsmodells zwischen dem HELLEUM und der Hochschullernwerkstatt Kommunikation und Sprache aufgezeigt. (DIPF/Orig.)
The educational component as a basis for the effective development of human capital in agricultural enterprises
Authors: Chekalovska Galyna , Ivashkiv Iryna
Published: February 2025

The article analyses the role and significance of the educational component as a crucial factor in the development of human capital in Ukraine’s agricultural sector. It highlights that, in the modern period, agricultural entrepreneurship in rural areas is primarily represented by agricultural cooperatives and family farms. However, the ongoing demographic crisis exacerbates the issue of attracting and retaining human capital in rural communities. The authors examine the theoretical aspects of the role and impact of education on the efficiency of human capital development.
A critical review of international and domestic academic literature was conducted using content analysis, revealing that, in many cases, the low quality of human capital in agriculture worldwide is primarily due to inadequate educational attainment. Employment levels across various economic sectors are assessed using indicators such as formal and informal sector employment. The article analyses the employment structure based on job types and educational levels, emphasizing that a significant portion of workers lacking relevant qualifications are unable to secure formal employment. Meanwhile, another segment of the workforce, possessing necessary skills and professional experience, often opts for unregistered employment, thereby forfeiting access to social benefits and protections provided through official employment.
The study examines key trends in employment levels concerning educational attainment, focusing on rural areas. A comparative analysis of employment structures based on education levels in Ukraine and its rural regions was conducted. The authors conclude that preserving human capital in the agricultural sector is directly linked to acquiring specific educational and professional qualifications, which can facilitate the adoption of new agricultural professions. This, in turn, generates income for rural households and enhances labour motivation and employment opportunities in rural communities
Optimizing Clustering Analysis to Identify High-Potential Markets for Indonesian Tuber Exports
Authors: Prasetya Dwi Arman , Sari Anggraini Puspita , Idhom Mohammad , Lisanthoni Angela
Published: February 2025

Agriculture is a key contributor to Indonesia's economic growth, with tubers representing the second most important food crop. Despite their significance, the export value of Indonesia’s tuber crops has not yet reached its full potential given the decline in the value of tuber exports since 2021. One of the contributing factors is the restricted range of export market options. This study aims to analyze export trade patterns to identify the most high-potential markets for Indonesian tuber commodities.  Clustering analysis is used as a key method to identify market locations by grouping countries based on similar trade characteristics. Clustering was conducted using the Gaussian Mixture Model (GMM), which enhanced by Particle Swarm Optimization (PSO) and evaluated by silhouette score and DBI. The dataset is collected from Indonesia’s Central Bureau of Statistics from 2019 to 2023, focusing on 5 kinds of tuber exports with total of 455 entries and 8 columns. Using the AIC/BIC method, the optimal number of clusters obtained is 2 which are low market opportunities (cluster 0) and high market oppurtunities (cluster 1). Results showed that the GMM model without optimization has silhouette score of 0.7602 and DBI of 0.8398, while the GMM+PSO model achieved an improved silhouette score of 0.8884 and DBI of 0.5584. Both score are categorized as strong structure but, GMM+PSO has higher silhouette score and lower DBI score, demonstrating the effectiveness of PSO in enhancing the clustering model’s performance. The key potential markets for Indonesian tuber exports are primarily concentrated in Asia, including countries such as China, Malaysia, Thailand, Vietnam, Hong Kong, and United States.
EFFECT OF OTAGO EXERCISE AND SQUARE STEPPING EXERCISE IN ELDERLY BALANCE
Authors: Wahyono Yulianto , Suryaningtyas Sri
Published: February 2025

Introduction: A decline in balance due to the ageing process can increase the risk of falls and potential
injury in older adults, leading to complications that impact their quality of life. To help maintain balance
in the elderly, interventions such as the Otago Exercise Program (OEP) and Square Stepping Exercise (SSE) have been
introduced. This study aimed to investigate the effect of OEP compared to SSE on balance in the elderly. Methods: This was a
quosi experiment. Thirty-four elderly individuals from an elderly community center were recruited and assigned to group 1
(OEP) (n=17) and group 2 (SSE) (n=17). Participants completed 12 exercise sessions over four weeks. Balance was measured
using the Timed Up and Go (TUG) test. Results: After the 4-week intervention, both groups showed signicant improvements in
balance (p = 0.000) from pre- to post-test. The post-test results of the two groups also showed a signicant difference (p = 0.044),
with the OEP group demonstrating a greater mean improvement (3.17) than the SSE group (1.97). Conclusion: Otago Exercise
program is more effective than Square Stepping Exercise in improving balance in the elderly
O levantamento histórico em arqueologia urbana no centro histórico de Salvador: uma análise dos processos do IPHAN (2016-2020)
Authors: Rocha Colpas Alexandre , Fagundes Morales Walter
Published: February 2025

O presente artigo busca ressaltar a importância da composição entre fontes históricas e arqueológicas em pesquisas arqueológicas desenvolvidas entre 2016 e 2020 no Centro Histórico de Salvador, Bahia, Brasil. Por se encontrar inserida em um ponto estratégico no Atlântico Sul, a cidade passou por um processo de urbanização a partir do século XVI por conta do fluxo de mercadorias e populações escravizadas até o século XIX. Ao longo do século XX, o centro da cidade passou por profundas transformações, entrando em decadência e sofrendo um processo de requalificação urbana. Essa revitalização, realizada pelo poder público no final do século XX, foi acompanhada de pesquisas arqueológicas que revelaram aspectos sobre as origens da cidade através de objetos, estruturas e vestígios dos povos que por ali passaram desde tempos pré-coloniais. Os dados obtidos, enriquecidas pelas fontes escritas e iconográficas, revelaram a cultura material da ocupação Tupiguarani, do primeiro Governo-Geral e do comércio transatlântico. Assim, o artigo discute como essas fontes permitiram aprofundar o conhecimento das práticas cotidianas e formas de apropriação do espaço e uma proposta para disponibilizar essas informações ao grande público pelo viés da Arqueologia Pública.
Upaya Penurunan Kasus TB Paru di Wilayah Kerja Puskesmas Kresek Kecamatan Kresek, Kabupaten Tangerang, Provinsi Banten
Authors: Aufatunnisa Fatimah , Syahputri Rahmi , Hafidza Azzahra , Sanjaya Juliana
Published: February 2025

data at the Kresek Community Health Center, the number of tuberculosis cases increased from January to May. Seeing this, it is necessary to carry out a community diagnosis approach to further analyze and identify the factors causing the increase in cases of pulmonary tuberculosis so that immediate intervention can be carried out to prevent the spread and reduce the number of new cases of pulmonary tuberculosis in the working area of the Kresek Community Health Center, Tangerang Regency. Objective: To enhance public awareness of TB, proper coughing, and handwashing within the Kresek Community Health Center’s operational area. Method: Utilizing the Blum Paradigm for community diagnosis to identify underlying causes, conducting mini-seurveys to gather data, the non-scoring Delphi method to prioritize problem, and fishbone diagrams to determine root causes of issues. Interventions include education on TB, cough etique and handwashing steps. Intervention is monitored using the Plan-Do-Check-Action  (PDCA) cycle, along with systemic approach to evaluation. Results: Lifestyle factors was contributing to hig TB cases according to the Blum Paradigm. Intervention I (Pulmonary TB) outcomes indicate 29 participants (80,5%)  experienced an improvement in post-test score compared to pre-test, wiht 32 participants (88,9%) achieving a post-test score ≥70. Intervention II (PHBS) outcomes indicate 34 participant (94,4%) showed an improvement in post-test score compared to pre-test, and 35 participants (97,2%) achieved a post-test score ≥70 and 6 randomly selected participants executed all two demonstration. Conclusion: There has been an improvement in knowledge regarding pulmonary TB, cough etiquette, and handwashing steps in the working area of Kresek Community Health Center.
INVESTIGATION OF THE SEED GERMINATION PARAMETERS AND MORPHOLOGY OF COTTON UNDER MODELED SALT STRESS CONDITIONS
Authors:   Center of Genomics and Bioinformatics of the Academy of Sciences of the Republic of Uzbekista, KAMBUROVA V.S. , SALAKHUTDINOV I.B. ,   Center of Genomics and Bioinformatics of the Academy of Sciences of the Republic of Uzbekista, BAZAROV D.K. ,   Center of Genomics and Bioinformatics of the Academy of Sciences of the Republic of Uzbekista,   Digital Technologies and Artificial Intelligence Research Institute, MAMATKULOVA SH.KH. ,   Center of Genomics and Bioinformatics of the Academy of Sciences of the Republic of Uzbekista, ISOMIDDINOVA O.L. ,   Center of Genomics and Bioinformatics of the Academy of Sciences of the Republic of Uzbekista, LATYPOVA E.A. ,   Federal State Budgetary Educational Institution of Higher Education "Penza State Agrarian University"
Published: February 2025

Soil salinization is a serious adverse environmental stress that severely limits the growth and development of plants and affects crop yields. The creation of salt-tolerant crop varieties using classical and molecular genetics methods, as well as the study, identification and understanding of the mechanisms of salt tolerance, open up wide-ranging opportunities in attempts to control this trait in plants. The article presents the results of the study of the germination parameters of cotton seeds and the morphology of the vegetative organs of the plants under modeled salt stress. The research subjects were varieties and lines of medium-fiber cotton of classical genetics and biotechnological gene knockout varieties of the Porlock series. The analysis of the results of the seed germination parameters: germination, mean germination time, germination index showed that the biotechnological gene knockout variety Porlock-4 was the most resistant to salinization (NaCl concentration 50, 100, 150 and 200 mM) and the line of classical selection Coker-312 was the least resistant. The investigations of the morphological parameters showed that an increase in the NaCl concentration up to 100 mM leads to a slowdown in root and shoot growth and an increase in biomass in both genotypes. However, the negative effect of NaCl was less pronounced in the biotechnological variety Porlock-4 than in the salt-sensitive line Coker-312.
ORGANIZATIONAL, ECONOMIC AND SPATIAL ASPECTS OF PLANNING THE DEVELOPMENT OF THE MATERIAL AND TECHNICAL BASE OF THE AGRI-FOOD SECTOR OF THE ECONOMY
Authors:   Federal State Budgetary Educational Institution of Higher Education "Penza State Agrarian University", IVANOV A.A. , SAMYGIN D.YU. ,   Federal State Budgetary Educational Institution of Higher Education "Penza State University", ALEKSEEVA S.N. ,   Federal State Budgetary Educational Institution of Higher Education "Penza State Agrarian University", MATVEEV V.A. ,   Federal State Budgetary Educational Institution of Higher Education "Penza State Agrarian University", BOTNAR R. ,   Federal State Budgetary Educational Institution of Higher Education "Penza State Agrarian University"
Published: February 2025

The article analyzes various sources of financing for the restoration and development of the material and technical base of agricultural commodity producers in modern conditions, including the current measures of state support. The key trends in the development of the material and technical base of agriculture, aimed at introducing high-performance agricultural machinery and equipment into production, have been identified. On the one hand, it provides an increase in labor productivity, reduces the cost per unit of production, solves the problem of the lack of highly qualified machine operators in the agricultural sector of the economy, and introduces intensive technologies of agricultural production. On the other hand, a drastic increase in the productivity of machinery leads to a significant increase in its costs and increases the loads per season. As a result, the risks of partial crop loss due to equipment failure during peak working hours increase, as it is difficult to replace a high-performance complex in a timely manner, and the acquisition and maintenance of reserve capacity is usually associated with high additional costs. The analysis of the supply of the main types of machinery in the crop production sector has shown that despite the above-average rates of renewal of the machinery and tractor fleet for the sake of retirement of worn-out equipment in many regions of Russia, the level of supply per 1,000 ha remains below the average indicators for the country and federal districts. To solve the problems of development of the material and technical base at a qualitatively new level, the article proposes a set of organizational and economic measures aimed at the development of the system of regional machinery and technological enterprises. The purpose of the scientific study is to determine a set of organizational and economic measures aimed at the development of the material and technical base of the agri-food sector of the economy using the example of crop production, taking into account the elimination of spatial imbalance in the availability of equipment.
REPRODUCTIVE ABILITY OF HOLSTEIN COWS OF DIFFERENT AGES
Authors:   Federal State Budgetary Educational Institution of Higher Education "Penza State Agrarian University", LYASHENKO V.V. , KAESHOVA I.V. ,   Federal State Budgetary Educational Institution of Higher Education "Penza State Agrarian University", GUBINA A.V. ,   Federal State Budgetary Educational Institution of Higher Education "Penza State Agrarian University", CHUPSHEVA N.YU. ,   Federal State Budgetary Educational Institution of Higher Education "Penza State Agrarian University", ZORIN L.N. ,   Federal State Budgetary Educational Institution of Higher Education "Penza State Agrarian University"
Published: February 2025

The reproductive function of an animal involves obtaining a similar animal for procreation. Reproductive abilities characterize the reproductive process more comprehensively. The article presents the results of the evaluation of reproductive traits of highly productive cows of different ages. The study was carried out under the conditions of a modern dairy complex on a herd of Holstein cows with a milk yield of over 11,000 kg per cow. Three groups of cows of the first, second and third lactations were formed. The calving result, service period, dry period, milk yield, the relationship between service period length and milk yield, the insemination rate and the utilization coefficient of the reproductive ability of the cows were investigated. It was found that mature cows produced more calves than first-calf heifers and second-calf cows, by 4.1 and 0.5 % respectively. Higher performance of heifers was observed in cows of the first (82.5 %) and second (64.8 %) lactations, which can be explained by the insemination of replacement heifers and first-calf cows with sexed semen. The duration of lactation is almost the same for animals in groups I and II and exceeds this indicator for cows in group III by 18.1 (p ≤ 0.001) and 11.5 days (p ≤ 0.01) respectively. The highest milk yield for the entire lactation and for 305 days of lactation was observed in cows in the second group, namely 13,238.6 and 11,491.2 kg respectively. In terms of lactations, a shorter service period was observed in the cows of the third group, which amounted to 138.5 days. No correlation was found between milk yield and a service period. Most of the animals in the second (48.1 %) and third (50.0 %) groups were fruitfully inseminated from the second time and a significant part of the first-calf cows the fourth time (28.2 %). The utilization coefficient of the reproductive ability and calf yield was highest in third lactation cows. The results of the study lead to the conclusion that the evaluated cows of the three groups are generally characterized by a satisfactory reproductive ability.
EXPERIMENTAL STUDIES ON AN AERODYNAMIC SEPARATOR
Authors:   Federal State Budgetary Educational Institution of Higher Education "Penza State Agrarian University", NOVIKOV I.O. , KUKHAREV O.N. ,   Federal State Budgetary Educational Institution of Higher Education "Penza State Agrarian University"
Published: February 2025

The amount of grain production requires special attention from the workers of the agro-industrial complex. On the basis of Penza State Agrarian University, an aerodynamic separator was designed and developed, which is used to separate the grain material into fractions and to clean it from light impurities. Experimental studies of the aerodynamic separator were also carried out in the laboratory of Penza State Agrarian University. The variety of soft winter wheat “Bezostaya-100” was selected as a research sample, as it is popular among agricultural producers in Penza region and neighboring regions.

As a result of the experimental studies, data were obtained on the dependence of the horizontal displacement L on the angle α of air flow transmission of the aerodynamic separator. Experimental evidence of the distribution of grain material through the grain collection bunkers (fractions) is presented in the form of graphs and diagrams. When analyzing the data obtained, it became clear that for this aerodynamic separator the most suitable angle of air flow transmission is α = 45 °, since at this value of the angle the maximum horizontal displacement L is achieved, which in turn is reflected in the quality of separation of the grain material.
Amniotic Band Syndrome Beyond Infancy: A Case of Lower Extremity Involvement in Adolescence
Authors: Tutcu Halis Kayhan , Vezirhüyük Mustafa , Cetin Burcu , Midi Ahmet
Published: February 2025

Objective: Amniotic band syndrome (ABS) is a congenital condition characterized by fibrous bands that constrict fetal structures, leading to a wide spectrum of anomalies. While typically diagnosed in infancy, ABS can present later in life with atypical manifestations. This report describes a rare case of late-presenting ABS in an adolescent, emphasizing the importance of considering this condition in older age groups.
Case: A 17-year-old female presented with numbness and pain in the left foot and ankle. Physical examination revealed a circumferential amniotic band proximal to the ankle joint, causing significant discomfort and functional impairment. Surgical intervention was performed to release the constriction, leading to symptom resolution and restoration of function.
Conclusion: This case highlights the need to include ABS in the differential diagnosis of adolescents with unexplained limb symptoms, even when the presentation is delayed. The favorable outcome underscores the importance of timely intervention, reinforcing the role of early recognition and multidisciplinary management in optimizing patient outcomes. The lower extremity localization further emphasizes the diverse clinical manifestations of ABS, advocating for a comprehensive approach to diagnosis and treatment.
Abordagens Cirúrgicas para Tratamento da Insuficiência Cardíaca Avançada: Comparação entre Implante de Coração Artificial e Transplante Cardíaco
Authors: Felipe Laurindo Couto  , Ana Kelly de Azevedo Gonçalves  , Caio Enzo Dantas de Paiva Queiroz  , Monaliza Carvalho Alves Feitosa  , Maria Eduarda Torreão Medeiros Teobaldo  , Bruno Rafael de Souza Honorato  , Brenda Tawares Batista  , Gabriela Júlia Pereira Chacon de Araújo  , Maria Cecília Vieira Stewart Thomaz  , Marialice Pinto Viana Correia  , Mary Morioka
Published: February 2025

O tratamento da insuficiência cardíaca avançada representa um desafio significativo na cardiologia, exigindo abordagens cirúrgicas de alta complexidade. As principais opções para esse tratamento se destacam o transplante cardíaco e o implante de coração artificial, cada um com indicações, benefícios e desafios específicos. Essa escolha  depende de fatores como a disponibilidade de órgãos para transplante, a condição clínica do paciente e a evolução tecnológica dos dispositivos de assistência circulatória. A pesquisa foi realizada no indexador PubMed, utilizando os termos “Insuficiência Cardíaca”, “Transplante Cardíaco”, “Coração Artificial”, “Dispositivos de Assistência Ventricular”, “Cirurgia Cardíaca” e “Complicações Pós-operatórias”, combinados pelo operador booleano AND, no intervalo de 2015 a 2025, nos idiomas inglês e português. Os resultados apontam que, embora o transplante cardíaco ainda seja considerado o padrão-ouro no tratamento da insuficiência cardíaca terminal, a falta de doadores e as complicações associadas à imunossupressão estimulam o avanço dos corações artificiais. Dispositivos de assistência ventricular e corações artificiais têm se mostrado eficazes como terapia de ponte para o transplante ou até mesmo como tratamento definitivo em determinados casos. Além disso, nota-se a importância de estratégias para reduzir complicações pós-operatórias, como infecções, tromboses e falência orgânica, otimizando tanto a sobrevida quanto a qualidade de vida dos pacientes submetidos a essas intervenções.
Alterações cardiovasculares e sistêmicas na Síndrome de Down: Impacto das cardiopatias congênitas e comorbidades associadas
Authors: Rodrigues de Carvalho Daniella , Muniz Maria Fernanda Dantas Giffoni , Souza Ana Beatriz Franco de , Barbosa Nayron Pereira , Brito Jaylla Debora Freitas , Souza Renata Pereira de , Litvin Rafael
Published: February 2025

Este artigo tem como objetivo realizar uma revisão da literatura científica sobre as alterações cardiovasculares e sistêmicas na Síndrome de Down, com ênfase nas cardiopatias congênitas, repercussões fisiológicas e impacto na qualidade de vida dos pacientes. Para isso, foram utilizados como motores de busca os indexadores PubMed, Scopus e Web of Science, utilizando os unitermos "Síndrome de Down, Cardiopatia congênita, Sopro cardíaco, Comorbidades sistêmicas". A revisão revelou que a Síndrome de Down está fortemente associada a anomalias cardiovasculares, sendo o defeito do septo atrioventricular a mais prevalente, seguido por comunicação interatrial e interventricular. Além das cardiopatias, indivíduos com Síndrome de Down apresentam maior predisposição a distúrbios visuais, hipotonia muscular e alterações na vascularização cerebral, o que pode contribuir para complicações sistêmicas. O diagnóstico precoce e o manejo multidisciplinar são fundamentais para melhorar a sobrevida e a qualidade de vida desses pacientes, destacando a importância do acompanhamento cardiológico e da intervenção precoce.
Utilização de Plasma Rico em Plaquetas e Plasma Rico em Fibrina em Ferida Crônica de Paciente Diabético: relato de caso.
Authors: Oliveira de Araújo Alves Ana Elizabeth , Marques Braga Ana Beatriz , Rodrigues da Silva Fernandes Beatriz , Bispo da Fonseca Margareth , Maraschine Barbosa Marianne , Firmino Lima de Oliveira Marina
Published: February 2025

Introdução: A importância do plasma sanguíneo, e suas propriedades cicatrizantes em tratamento de feridas crônicas é uma terapia promissora na medicina regenerativa. O plasma rico em plaquetas é extraído do sangue venoso, composto de células responsáveis pela ativação da defesa do organismo. Sua aplicação em feridas crônicas junto com a fibrina rica em plaqueta, promove aceleração do processo de cicatrização e regeneração tecidual. Objetivo: Realizar procedimento de aplicação de plasma rico em plaquetas (PRP) e fibrina rica em plaquetas (PRF) em ferida de um paciente diabético avaliando a eficácia e segurança do tratamento. Métodos: Trata-se de um relato de caso, realizado em uma clínica escola de um centro universitário privado do Distrito Federal. Foram coletados dados clínicos relatado em entrevista com paciente, fotodocumentação em todas as aplicações e o paciente foi orientado sobre assinatura do termo de consentimento livre e esclarecido. Foram realizadas coletas de sangue em cada sessão. Este foi centrifugado a 1800 rpm para obtenção do PRP e PRF para posterior aplicação. O concentrado foi quantificado em relação a sua densidade. Resultados: Ambas as aplicações de PRP e PRF nas feridas resultou em uma melhora importante na cicatrização e regeneração tecidual. Observou-se uma redução no tamanho da ferida crônica e oxigenação tecidual.  Conclusão:  Com base nos resultados obtidos, pode-se concluir que as aplicações de plasma foram um mecanismo auxiliar eficaz e relevante na recuperação da ferida do paciente, demonstrando potencial para ser um tratamento valioso em casos semelhantes.
O IMPACTO DA MICROBIOTA CUTÂNEA NA RESPOSTA TERAPÊUTICA DA DERMATITE ATÓPICA
Authors: Lênio Airam de Pinho  , Gustavo Cavalcante de Freitas  , Charlene Glaucia Nunes de Almeida  , Marcela Lourenço Lacerda  , Fernanda Oliveira Brito dos Reis  , Lourdes Judith Medeiros Max  , Angélica de Almeida  , Isaque Ramos Silva  , Gabriela Romano de Oliveira  , Rodrigo Daniel Zanoni
Published: February 2025

Trata-se de uma revisão integrativa da literatura, Foi possível assim estruturar a seguinte pergunta norteadora: “Quais os impactos da microbiota cutânea na resposta terapêutica da dermatite atópica?”. Foi feito um levantamento através da biblioteca eletrônica sendo a Biblioteca Virtual em Saúde (BVS), sendo selecionada as seguintes bases de dados: Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e Medical Literatures Analysis and Retrieval System Online (MEDLINE), foi utilizado os descritores consultados nos Descritores em Ciência e Saúde (DeCS), no mês de fevereiro de 2025, sendo: “Microbiota”, “Dermatite atópica” e “Terapêutica”, utilizando o operador booleando AND entre os descritores quando combinados.  Após a aplicação dos critérios de elegibilidade foram utilizados dez artigos selecionados ao total. De acordo com os estudos encontrados, a microbiota cutânea de pacientes com dermatite atópica (DA) difere significativamente da microbiota de indivíduos saudáveis. Uma das alterações mais frequentemente observadas é a redução da diversidade microbiana, ou seja, o número de diferentes espécies de microrganismos presentes na pele. Essa diminuição na diversidade pode levar a um desequilíbrio na comunidade microbiana, tornando a pele mais vulnerável a infecções e inflamações. Em suma, a microbiota cutânea emerge como um ator crucial no intrincado cenário da dermatite atópica (DA), exercendo influência tanto na patogênese da doença quanto na resposta aos tratamentos. As alterações observadas na microbiota de pacientes com DA, como a redução da diversidade e o aumento da abundância de espécies específicas, como o Staphylococcus aureus, contribuem para a disfunção da barreira cutânea, a inflamação crônica e a exacerbação dos sintomas.
NÍVEIS DE ATIVIDADE FÍSICA DE IDOSAS ATIVAS SUBMETIDAS A PROGRAMAS DE MUSCULAÇÃO, DE DANÇA E DE MEDITAÇÃO
Authors: Cruz Thales Henriques Pires , Pessoa Arthur Modesto , Bentes Joubert Marinho da Silva , Araújo Gloria Cristina Miranda , Caldas Reinaldo Dias , Palheta Eder do Vale , Rodrigues Enivaldo Cordovil , Sá Nonato Marcio Custódio Maia , Moura Adriana Maria Leão de , Sa João Gabriel de Oliveira , Maciel Adriano Cruz da Costa
Published: February 2025

O objetivo do estudo foi comparar os níveis de condicionamento físico (resistência aeróbica, força e flexibilidade) em idosas ativas (N=55) da Casa do Idoso na Cidade de Belém-PA, Brasil.Também participaram desta pesquisa 10 idosas sedentárias, voluntárias, que pertencem à comunidade ao redor da casa do idoso que foram divididas em quatro grupos: de musculação (GMusc: n=20; idade=67.2±5.66 anos; IMC=26.77±4.53 kg/m2); de dança (GDan: n=20; idade=68.5±3.47 anos; IMC=26.53±2.91 kg/m2), de meditação (GMed: n=15; idade=68.1±4.37 anos; IMC=25.95±2.73 kg/m2), e controle (GC: n=10; idade=66.1±2.56 anos; IMC=27.12±5.68 kg/m2). Cada grupo estava realizando a atividade física a, no mínimo, 6 meses. Foram aplicados os testes de caminhar 6 minutos (C6M); sentar-e-levantar (SL); flexão e extensão de cotovelo (Flext/Ext) e o Normalflex para medir o nível de condicionamento físico. O teste de Kruskal-Wallis apontou que o GMusc, o GDan, e o GMed apresentaram valores significativamente (p<0.05) melhores para os níveis de condicionamento físico que o GC, porém não mostraram diferenças entre si. Não foram encontradas outras diferenças entre os outros testes. O estudo sugere que as atividades que propiciem estímulos de maior intensidade durante os exercícios podem melhorar o condicionamento físico.
MÉTODOS DE PREVENÇÃO AO TRAUMA DE FACE EM ACIDENTES DE TRÂNSITO COM ÊNFASE PARA FRATURAS NASAIS: UMA REVISÃO DA LITERATURA DE BASE NACIONAL
Authors: Lima Anycia Laura Oliveira da Silva Matos , Santos Ana Clara Ferreira dos , Rodrigues Eduarda Ellen da Silva , Paiva Danielle Cardoso Batista de , Falcão Emily Kerolaynne Gomes , Oliveira Jeanete Marília Santos Lino de , Silva Kisla Monteiro da , Santos Lívia Nayane Simão dos , Silva Myllena Galvão da , Vasconcelos Rafaela Brito
Published: February 2025

Introdução: O trauma facial decorrente de acidentes de trânsito é uma ocorrência frequente e de grande impacto nos sistemas de saúde, com as fraturas nasais sendo a lesão mais comum. A posição proeminente do nariz e sua estrutura frágil tornam essa região especialmente vulnerável durante colisões. Embora o avanço da tecnologia de segurança veicular tenha reduzido a mortalidade em acidentes, as fraturas nasais ainda permanecem frequentes devido a comportamentos inseguros no trânsito, como a não utilização do cinto de segurança e o excesso de velocidade. Diante disso, é fundamental explorar e enfatizar medidas preventivas que possam minimizar a ocorrência desse tipo de lesão. Objetivos: O presente estudo objetivou revisar a literatura no que se refere as principais medidas preventivas que podem ser adotadas para redução da ocorrência de fraturas nasais em acidentes de trânsito, com foco nos equipamentos de segurança e métodos preventivos relacionados ao veículo.
 
Métodos: A revisão bibliográfica se deu através da busca nas bases de dados SciELO, Biblioteca Virtual em Saúde (BVS) e em dados Nacionais do Governo. Foram utilizados os descritores em português “Prevenção de Acidentes” “Segurança no Trânsito” “Septo Nasal” e “Cintos de Segurança” e suas correspondentes em inglês, dentro do período dos últimos 18 anos. Resultados: Mediante a revisão bibliográfica, há inúmeros métodos para prevenção das fraturas faciais, dentre os quais, destacam-se os cuidados automotivos, tanto dos motoristas e ciclistas, bem como do estado do automóvel, como a devida revisão no sistema de pneus e freios. Conclusões Finais: A prevenção de fraturas nasais em acidentes de trânsito está diretamente relacionada ao uso de equipamentos de segurança automotiva, como o cinto de segurança, e capacetes, bem como, no uso de medidas preventivas ligadas ao veículo, tais como manutenção dos freios, pneus, uso correto do sistema de suspensão, e ainda, manutenções regulares do veículo. A conscientização da população sobre o uso correto desses dispositivos e a implementação de veículos com tecnologias de proteção avançada são medidas fundamentais para reduzir a incidência de trauma facial. O compromisso com a segurança no trânsito pode salvar vidas e prevenir lesões debilitantes, como as fraturas nasais com sequelas permanentes.
TRANSABDOMINAL PRE-PERITONEAL INGUINAL HERNIA REPAIR: EVALUATING EFFICACY, SAFETY, AND RECURRENCE RATES
Authors: Pereira Thais Pâmela Morais , França Camila Kubiake , Cavalcante Lohana Assunção , Chaves Isabela Luiza Souza , Silvestre Neto Thales , Martins Mabylle Carneiro , Lucena Pedro Henrique Pereira , Carvalho Lorena Mazzaro de Almeida de , Souza Rebecca Cavalcante Pio de , Zucoloto Rafael Puppim
Published: February 2025

Este estudo avaliou a técnica laparoscópica TAPP (Transabdominal Pré-Peritoneal) na reparação de hérnias inguinais, com foco na eficácia, segurança e taxas de recidiva. A TAPP, uma abordagem que utiliza acesso transabdominal, permite excelente visualização anatômica, facilitando o posicionamento preciso da tela e a correção de defeitos bilaterais. Os resultados mostram que a técnica é segura, apresentando baixas taxas de complicações e boa eficácia na prevenção de recidivas. A facilidade técnica e a curva de aprendizado mais curta tornam a TAPP uma opção atrativa, especialmente em centros de treinamento. Conclui-se que a TAPP é uma técnica confiável e eficiente, oferecendo bons resultados para a correção de hérnias inguinais, especialmente quando realizada por cirurgiões treinados.
NON-TRADITIONAL APPROACH TO THE TREATMENT OF MYOFACIAL PAIN SYNDROME
Authors: Urazbaeva G  , Kim O.A
Published: February 2025

Pain is one of the leading complaints in the ambulatory setting. The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 demonstrated that low back pain, neck pain and other musculoskeletal pain complaints are the leading causes of morbidity globally in terms of years lived with disease. The frequency of acute musculoskeletal back pain in the population averages 31%, while the transition to a chronic form is observed in 38% of patients, in 40% of cases it is not possible to relieve chronic pain syndrome. The article presents a brief review of literary sources of the last 10 years, covering issues of etiopathogenesis, diagnostics and non-traditional methods of treatment of patients with myofascial pain syndrome.
KEY WORDS: Myofascial Pain Syndrome, Trigger Point, Manual Therapy, Dry Needling
INSTITUTIONAL DEVELOPMENT OF THE THERMOMETERNIZATION MARKET IN THE FOCUS OF MAIN STAKEHOLDERS
Authors: Maksymov А. , Lysytsia N. , Podoynitsyn S.
Published: February 2025

Abstract. The development of any markets is often influenced by the institutional framework that shapes their development. The thermal retrofit market, defined as a sector focused on the production, distribution and application of energy-efficient building technologies, has experienced significant growth and transformation in recent years. This study examines the institutional development of the thermal retrofit market, highlighting the roles and interactions of key stakeholders.
Retrofitting is crucial in various industries, including the residential sector. The war and the energy crisis highlighted the critical role of thermal retrofitting in construction, fueling unprecedented demand and rapid market expansion. Understanding the institutional factors that have shaped the development of this market can provide insight into its future trajectory and inform policy decisions.
The study included a comprehensive literature review, analysis of market reports by key stakeholders including manufacturers, regulators, industry experts and end users.
The main stakeholders are manufacturers, suppliers, designers, developers, contractors, regulators, research institutions and consumers. Each group plays a special role in shaping market dynamics. Manufacturers drive innovation, suppliers influence demand, regulators set standards, research institutions promote technological progress, and consumers determine market trends.
To promote the sustainable growth of the retrofit market, recommendations are made such as fostering collaboration between customers, contractors, manufacturers, regulators and research institutions to optimize innovation and compliance processes, investing in research and development to drive technological progress and meet the needs of the evolving market, strengthening regulatory framework, harmonizing international standards to facilitate access to the global market and ensure product safety and efficiency, provide support to SMEs in navigating regulatory requirements and market competition.
The institutional development of the thermomodernization market is shaped by the complex interaction of stakeholders, regulatory frameworks, and technological advances. Understanding these dynamics is critical to driving sustainable market growth and ensuring accurate and reliable energy-saving solutions are available. A comprehensive analysis of the evolution of the market and strategic recommendations for interested parties will allow to navigate future challenges and opportunities for the development of the thermomodernization market.
Captain John Laskey, Dr Peter McDougall and the roseate tern, Sterna dougallii Montagu, 1813
Authors: Hancock E.G.
Published: February 2025

The roseate tern, Sterna dougallii was described by Montagu in his 1813 Supplement to his Ornithological Dictionary in which he provided considerable detail on how the specimens came to him from Glasgow. Recent research by Mearns & Mearns has revealed biographical details of the finder, Dr Peter McDougall. This article provides further information on the role of Captain John Laskey leading to the publication of Montagu’s description, and on preserved examples of the roseate tern from McDougall’s collection that are additional to the type specimen.
In good company: an appreciation of the Scottish naturalist William Baird MD, FLS, FRS (1803‒1872)
Authors: Moore P.G.
Published: February 2025

Born in Berwickshire (Scotland), in his youth William Baird (1803‒1872) voyaged first to the West Indies and South America (1823) and then to the Far East, latterly in the employ (for a decade) of the Honourable East India Company as a surgeon (although precisely where he obtained his MD is a moot point) collecting specimens en route. Later he joined the staff of the zoological department of the British Museum (Natural History), spending 30 years there and publishing widely. He has been criticised by some, unfairly and inaccurately I am not alone in contending, for his modest contribution to science. William Stearn’s derogatory comments regarding Baird’s malacological output are ascribed to ignorance of the true scope of Baird’s responsibility for “Mollusca and lower animals” at the British Museum. Charles Darwin’s description of Baird as “indolent” provoked this reappraisal of his contribution to science. In seeking to rescue Baird’s reputation I examine his life and times, set his contribution within its wider social context, and present a detailed bibliography of his publications.
Witness Testimony Based on Hearsay in Russian Criminal Procedure: Issues, Solutions and Future Perspectives
Authors:   Lomonosov Moscow State University, Larionov Pavel A.
Published: February 2025

The lack of fundamental developments at both the legislative and doctrinal levels in the field of hearsay evidence leads to several issues that undermine both the private interest of the accused in protection against unfounded accusations and the public interest of society and the state in establishing an effective criminal justice system. These issues are most acute when the defense attempts to adjust the evidentiary base by excluding such evidence as inadmissible. Among the latter, the assessment of hearsay evidence presents the greatest difficulties due to legislative imprecision. An analysis of relevant case law has not only confirmed the hypothesis of the problematic approach to evaluating such evidence but also allowed for the formulation of proposals for extralegislative adjustments to the law enforcement course.
Automatic Pulmonary Nodule Detection and Management System
Authors: Ji Zhanlin , Hao Shengnan , Pang Jianhua , Ganchev Ivan
Published: February 2025

This paper presents a self-developed automatic pulmonary nodule detection and management system, built and operating on top of the IoT platform EMULSION as an effective tool for physicians and patients to conduct preliminary diagnoses of lung diseases and detect potential pulmonary-nodule-related health issues. The elaborated system architecture is described, including its overall structure, main functional modules, and their display pages. Providing a more convenient way for physicians to systematically handle and cure their patients, the designed and implemented system helps alleviate the workload of physicians while also giving patients more opportunities for follow-up treatment.
Treatment of intermediate-to-advanced unresectable hepatocellular carcinoma is shifting toward a multidisciplinary strategy that includes multiple modalities as needed
Authors: Sato Ken
Published: February 2025

In the recent issue of the World Journal of Gastroenterology , Han et al compared the efficacy of and adverse reactions to bevacizumab versus lenvatinib as molecularly targeted agents in combination with interventional therapy and immunotherapy (IMT) to treat intermediate-to-advanced unresectable hepatocellular carcinoma. No significant differences in efficacy or adverse reactions were observed between bevacizumab and lenvatinib. This study is highly promising because in some regions, e.g. , Japan, the combination of molecularly targeted therapy with IMT is fixed because of insurance restrictions, and some molecularly targeted agents cannot be combined with IMT. Further studies using these three modalities are expected to be conducted in the future. Additionally, because advanced radiotherapy modalities have recently been established, the number of combinations continues to increase, and further evidence regarding combination therapy, which is the cornerstone of personalized medicine, needs to be accumulated.
Advances in imaging techniques for tumor microenvironment evaluation in hepatocellular carcinoma
Authors: Wang Li-Li , Zhang Fa-Chang , Xu Han-Xin , Deng Dian-Dian , Ren Bing-Jie , Tan Qi , Liu Ya-Xin , Zhao Wen-Hui , Lu Jia-Le
Published: February 2025

The tumor microenvironment (TME) plays a critical role in the development and treatment of liver cancer, which ranks sixth in incidence and third in mortality worldwide, according to the “Global Cancer Statistics 2022”. Hepatocellular carcinoma (HCC), the most common form of liver cancer, is heavily influenced by the TME, which affects tumor growth, invasion, metastasis, and the response to various treatments. Despite advancements in surgery, liver transplantation, targeted therapies, and immunotherapy, the complexity of the TME often limits treatment efficacy, especially in advanced-stage HCC cases. The TME consists of a dynamic interaction between tumor cells, immune cells, fibroblasts, blood vessels, and signaling molecules, all of which contribute to cancer progression and therapy resistance. Assessing the HCC TME is essential for designing effective, personalized treatments and improving patient outcomes. Recent research highlights the value of imaging technologies as non-invasive tools to evaluate the TME, offering new possibilities for more targeted therapies and better prognosis monitoring in HCC patients.