bluuebunny/crossref_metadata_2025 huggingface dataset:
DESIGN OF ELECTRONIC FILING SYSTEM USING IMAGEWARE SCAN MANAGER IN BANK BJB KCP SAMARANG
Authors: Putri Ramadhany Audry
Published: February 2024

The archive system at Bank BJB KCP Samarang was initially not optimal, as evidenced by several problems that arise because of archives, such as the length of time for finding archives, archives are not neatly arranged, and there is no archive lending system. This can interfere with the work of employees. This project aims to design an electronic filing system at Bank BJB KCP Samarang using ImageWare Scan Manager. The work procedures carried out included applying for permits, interviews, identifying problems, designing programs, making programs, testing, evaluating, and finally making a manual for handling archives. The result of this archival system design is that the archive storage system used is a subject archive storage system based on the name of the credit lending category and a chronological storage system based on the year of the archive, as well as electronic archive storage using the four existing structures in the application, namely workgroups, worksheet templates, worksheets, and fields. For archive storage procedures there are four stages, namely login workgroup, open worksheet, index data, and import documents. Furthermore, the recovery of archives is carried out in four stages, namely requesting, searching, finding, and recording borrowed archives. Based on the results of tests using alpha beta testing, no errors were found and can facilitate archive discovery and facilitate work, so this application can be used as an alternative in archive storage.
Academic Performance of Learners using Bacolod Compendium 61 Materials: Basis for an Enhancement Plan
Authors: M Tompong Febe , Pamela S Guanzon Pinky
Published: February 2024

This study aimed to determine the academic performance of learners using Bacolod Compendium 61 as supplementary instructional materials in teaching Grade Two Araling Panlipunan in seven (7) elementary schools of District 7 during the school year 2022-2023. Bacolod Compendium 61 are competency-based supplementary learning resources anchored on Grade 2 Araling Panlipunan coverage “Ang Komunidad Noon at Ngayon. Respondents of this study were Grade 2 teachers and learners. The variables for the teachers included in this study were age, sex, length of service, highest educational attainment, and type of school. The areas of the effectiveness of Bacolod Compendium 61 are alignment of content, quality, and usability or ease of use. Frequency and percentage were utilized to determine the demographic profile of the teachers. The mean was employed to determine the effectiveness of Bacolod Compendium 61 materials. Frequency and percentage were used to determine the academic performance of learners. To determine the significant difference Mann-Whitney Test was used. Goodman-Kruskal’s Gamma (G) or Gamma Coefficient Formula was used to determine the relationship. Three (3) experts validated the researcher-made questionnaires that were used in this investigation. It was conducted at Andres Bonifacio Elementary School I with thirty (30) teacher-respondents. During the actual data gathering, information was gathered from three hundred eighty-one (381) learners and (forty-six) 46 teachers in Grade 2.
Main objective of this study was to evaluate the Bacolod Compendium 61 materials' efficacy in three (3) areas namely: Alignment of content, quality of materials, and ease of use. Results of the study showed that the level of academic performance of learners using Bacolod Compendium 61 supplementary materials as to the alignment of content, quality, and usability/ease of use were very high. This scientific investigation further proved that the level of academic performance of learners was outstanding as per use of Bacolod Compendium 61 Materials. Thus, the positive feedback of this research, highly recommends the full utilization of Bacolod Compendium 61 Materials in 46 elementary schools in the Division of Bacolod City. The conduct of SOK-SAY-LYMPICS: Bacolod Compendium 61 Quiz shall serve as assessment of learning on localization and indigenization is hereby recommended to be done yearly which shall be participated by 100% of the elementary schools in SDO Bacolod City. Other similar learning resources are hereby recommended to be crafted that can also be used as supplementary learning and reading remediation materials. Future researchers are highly encouraged the conduct of sequel researches highlighting on the effectiveness of localized resources in one’s local communities which aims to produce 21st century learners that are globally competitive with in-depth pride of one’s rich local cultural heritage.
Análisis de la siniestralidad del sector asegurador de Guayaquil y Quito durante el perioro 2012-2013
Authors: Macuy-Calle José , García Paola , Behr Judit , Garcés María , Feijoo Karen
Published: February 2024

La actividad del sector asegurador depende de diversos factores que son condicionantes o impulsadores. Uno de ellos es la siniestralidad, debido a que permite estimar las debilidades y fortalezas de un sistema de prevención en una institución de seguros. Esta investigación tuvo como hipótesis comprobar que existe un crecimiento en la demanda incitada por un aumento en siniestralidad. Durante el periodo de análisis, el propósito fue determinar aquellos factores que delimitan la dirección del costo del seguro en el mercado ecuatoriano, en relación siniestra pagados/primas cobrada; para observar las expectativas y perspectiva de riesgo e incertidumbre. La investigación fue de tipo exploratoria y el método aplicado fue el cuantitativo, debido a que se realizó un análisis y pruebas estadísticas de una base de datos extraída de la Superintendencia de Bancos y Seguros. Los principales resultados fueron que los seguros sufren distintos cambios y variaciones, dependiendo del ramo de sector y de la siniestralidad. En esta investigación se llegó a la conclusión de que no existe un crecimiento en la demanda de seguros incitado por un aumento del nivel de siniestralidad. Por lo tanto, la hipótesis establecida no se valida.
تطبيقات واستخدامات المواد النانومترية في المجالات الطبية والصيدلانية
Authors:   University of Zawiya, Agena Ahmed.SM
Published: February 2024

Nanomaterials are characterized by highly effective physico-chemical properties, such as a large surface area to mass ratio, which differ from bulk materials of the same composition, and these properties can be used to overcome some of the obstacles that affect traditional therapeutic and diagnostic factors, as the application of nanomaterials is increasing in Medical and pharmaceutical sciences quickly and offers excellent prospects. This paper presents the importance of the developments of nanomaterials with less toxicity and greater efficacy in the fields of imaging, diagnostics, disease treatment, drug delivery and tissue engineering, although these areas are still in their infancy, the current results clearly show enormous potential. Key words: efficacy, drugs, nanomaterials, toxicity
Identity Markers in the Georgian Narrative Sources of the Middle Centuries (Historical-Anthropological Analysis)
Authors: Gudushauri Tinatin , Sanadze Manana
Published: February 2024

The Article deals with the issue of revealing the identity definingmarkers in the Georgian narrative sources of the middle centuries(“The Life of Georgians” and hagiographic works). Main characteristics,considered to be important according to the Georgianhistorical material from the points of view of determining “us”group belonging and identifying distinctness of one ethnicity fromthe other ones, have been highlighted. The point of view statingthat the identified markers are in compliance with the attributiveand interactive paradigms of ethnicity, has been expressed.
Nuclear Proliferation of the Islamic Republic of Iran: Challenging the Balance of Power in the Middle East
Authors: Kvamladze Tato
Published: February 2024

Few topics in international relations consistently attract as muchacademic and policy interest as nuclear proliferation. Literatureon the subject tends to focus on the following questions: Why dostates seek nuclear weapons? How do they acquire the componentsnecessary to build them? What are the consequences of nuclearproliferation? Does nuclear proliferation change the balance ofpower? These issues will remain salient in the years to come asthe Iranian nuclear weapon programme continues, heightening thecrisis between regional leading states.
Forecasting Georgia Economic Growth 2020-2030
Authors: Raupp Edward R.
Published: February 2024

Firms, households, government agencies, and non-government organizations rely on forecasts when making decisions regarding the allocation of scarce resources. This paper develops evidence-based forecasts for key macroeconomic variables for the Republic of Georgia. Sources of data include the International Monetary Fund’s World Economic Outlook, The World Bank, and others. We use, primarily, exponential smoothing models generated by the statistical application Forecast Pro 100 to generate forecasts with 95 percent confidence limits. Finally, recognizing the high degree of uncertainty associated with long-term forecasting, we include scenarios to generate high, middle, and low values for the key variables. Our analysis shows population, a key economic resource, to be declining, along with the labor force participation rate, after a considerable rise. Gross fixed capital formation appears to be rising, while total reserves (including gold) is holding steady. With real GDP rising at an average rate of about five percent over the past decade, our forecast shows GDP continuing to increase over the next decade, along with GDP per capita, indicating a rising level of general wellbeing. Georgia’s inflation rate is low, and there is no credible evidence that the rate of inflation will accelerate in the coming years. We develop three scenarios for economic growth for Georgia for the period 2020-2030. All three scenarios – low, medium, and high–show continued healthy growth.
For the Issue of Language as a Relationship, Culture and Nation Awareness
Authors: Shavtvaladze Nana
Published: February 2024

When teaching Georgian as a foreign language, not only the alphabet,morphological-syntactic, stylistic and lexical queriesare taught, but also the details of the national consciousness areshown. These details make one unity that determines the character,habits, traditions and actions of the nation.Foreign learner is interested in the whole cultural face of this orthat nation. This is why such request was brought by the life oftoday`s world. American Erin Meyer answered the challenge withthe book “The Culture Map”. You can find many nations with theirpractical views and cultural attitudes.Georgia`s place in this culture map was very interesting. Languageis learnt because of the communication – communication determinesthe cultural form – cultural view determines the mentalityof the nation, its consciousness. Language is an opportunity, it`s aweapon to codify the nation. If there is not this or that word, signifiesthat the nation has not thought of it, it hasn`t needed it.It is a question statement. We should build our cultural map, whichimplies and consumes of many things. Individuals, especially intellectuals,create the epoch, influence the generation, but determiningthe mentality is perceived according to the nation`s actions andis represented by the language.
Mountain Region Development Strategy, Principles of Architectural-Spatial Organization Urban Areas and Housing
Authors: Laghidze Nino , Lagidze Ana
Published: February 2024

In this working paper, the current situation in the mountainous villages of the eastern part of Georgia, as well as urban-social and economic development potential and others, is studied. Mountainous villages need some fundamental functional planning and structural changes. It is noted that when deciding urban-social and architectural-planning questions, natural-climatic factors’ complexes should be considered: Difficult relief, its shape, its inclination and articulation, its climate and landscape variability by the vertical zoning, etc. In this work paper, we discuss the development problems of mountainous regions. Nowadays, there are severe problems in the mountainous villages: Lack of land, less competition, and technological backwardness of agricultural products. In winter, this area is almost empty of its difficult environmental conditions. Foreign experiences have been studied to plan the mountain settlements and formation-development principles, which could be used for the destination of architectural planning development in the mountainous part of east Georgia. It has been determined that it’s essential to form the mountainous regions as the general urban area to develop agriculture recreation and industry as well as agriculture recreation and tourism. According to the united urban planning development tendencies, development principles have been formed step bystep in the mountainous inhabited regions in the eastern part of Georgia.
Incommunication, an Essential Concept in Contemporary Political Communication
Authors: Wolton Dominique
Published: February 2024

Communication and incommunication are inseparable, but incommunication is the condition for communication, and can no longer be considered as “the failure of communication”. Incommunication and otherness are complementary for thinking about the difficulties linked to the illusions of the “communication society”. Europe is only a sum of incommunications and only endless negotiations prevent failure, whether about the enlargement process or the incessant resolution of crises. With incommunication, we rediscover the importance of the concept of otherness. Incommunication is an integral part of political construction. To revalue incommunication, and all the contradictory dimensions of history and politics, is to escape the constant devaluation of communication, often reduced to attempts at manipulation, and to legitimize intercomprehension as a modest but essential tool for the organization of debates. Incommunication, negotiation, and translation: three essential concepts to try to manage the question of otherness.
The Media War: Strategies and Escalations
Authors: Modreanu Simona
Published: February 2024

The invasion of Ukraine by Russia on February 24, 2022, caused a real planetary shock, not only on the battlefields but also in terms of the multiplication of the components of a hybrid war. Information and disinformation go hand in hand on both sides, with significant conflicting approaches that illustrate two different worldviews.
Clustering Professional Communication
Authors: Bagaeva Irina
Published: February 2024

This article examines the challenges associated with selecting appropriate methodologies and principles for organizing the intricate thematic dimension of professional communication. By employing suitable methods, fragmented knowledge can be synthesized, while the explanatory principle facilitates the identification of essential attributes within a given cluster. The rational application and integration of fundamental scientific principles, concepts, and methodological approaches establish specific criteria for objectively evaluating the construct of a cluster. Clustering is recognized as one of the most effective techniques for segmenting the diverse thematic dimensions of professional communication. The article analyzes the “Politics” cluster as an exemplar within the broader thematic dimensions of professional communication. The clustering process within the thematic dimension aims to encompass an expansive scope with a sense of comprehensive coherence. The model for clustering the thematic dimension provides a range ofconstraints and assumptions crucial in creating appropriate constructs.
For Specification of One Context of “The Passions of Saint Shushanik” (“He visited a holy man in his place (vani)…)
Authors: Mrevlishvili Nana
Published: February 2024

The article deals with the specification of the context of one phrase from “The Passions of Saint Shushanik” – “He went to a holy man at his residence (vani) to ask about something.” This excerpt from the text gives rise to some questions: 1. Who is the holy man? Is he a secular or a religious figure? 2. Why do Iakob and Apots go to him – to ask about something or to make a visit tohis place? 3. What could ‘vani’ (residence, monastery) mean in this context? The article discusses E. Chelidze’s interpretation of this phrase, according to which the holy man is a religious figure. At the same time, Apots and Iakob go to pay him a visit at his place. Taking specific arguments and the reading preserved in the earliest copy (A 95) of “The Passions of Saint Shushanik” into consideration, we try to show that the holy man must be a churchman, and Apots and Iakob went to him to ask about something. At the same time, the word vani probably means where a religious person resides – a monastery or a cell rather than a house.
Clientelism in Georgia
Authors: Jikia Tsotne
Published: February 2024

This paper aims to examine clientelism in Georgian politics. It is one of the most severe cases of corruption since it substantially assists in establishing an anti-democratic regime in the state. Clientelism has been seen as a corollary of democracy, especially in the early phases of democratization. After 30 years of attempting to bring Georgia closer to European principles and complete integration with the West, Georgian politics has been dominated by informal ties that cause significant damage to state institutions. This study investigates politically motivated corruption-related activities using various sources and documentary materials. Additional factors that influence the creation of clientelism are also taken into account.
The First Work on Oliver Cromwell in Georgia
Authors: Chikavidze Tsira
Published: February 2024

In 2022, the publishing house “Logos” published the book “Oliver Cromwell. Puri-tan, Captain, Statesmen” (441 pages) by Ivane Menteshashvili, Doctor of Historical Sciences, Professor, Fellow International Napoleonic Society. Ivane Manteshashvili is a Georgian historian, senior scientist at the Georgian National Museum, asso-ciate professor at the University of Georgia, and simultaneous interpreter and poetry translator in Georgian historiography, Iv. Menteshashvili is well-known through his research and works on the history of England and France, mainly: “History of En-gland, “Love and Power. Elizabeth I Tudor”, “Napoleon,” Cardinal Richelieu”- in Georgian, “The Falkland Islands. History of the Conflict,” “Power and Hero. Na-poleon Bonapart,” “Transcaucasia in British Russian Competition in 1880-1914,” “The Contiguity of Civilization of the Western and the Eastern Civilizations During the Activity of the British East India Company in India” -in Russian, etc. By the way, Professor Ivane Menteshashvili partly dealt with Oliver Cromwell in his book “Power and the Heroes Born of Revolution” (in Russian), where he gives portraits of three historical persons: Cromwell, Napoleon, and Stalin.
Pengaruh Perceived Organizational Support dan Psychological Empowerment terhadap Job Performance yang Dimediasi oleh Organizational Citizenship Behavior pada Kyriad Muraya Hotel
Authors: Rida Raihati Miska  , Amri
Published: February 2024

The sample includes all employees at the Kyriad Muraya Hotel, totaling 110 uses the Structural Equation Modeling (SEM) method. The research results show that there is a positive and significant influence of Perceived Organizational Support and Organizational Citizenship Behavior on Job Performance. There is a positive and significant influence of Perceived Organizational Support and Psychological Empowerment on Organizational Citizenship Behavior. There is a positive and significant influence of Perceived Organizational Support on Job Performance which is mediated by the Organizational Citizenship Behavior variable. And there is a positive and significant influence of Psychological Empowerment on Job Performance which is mediated by the Organizational Citizenship Behavior variable.

Sampel penelitian ini seluruh karyawan Hotel Kyriad Muraya yang berjumlah 110 orang dengan metode SEM. Hasil penelitian menunjukkan bahwa terdapat pengaruh positif dan signifikan Perceived Organizational Support dan Organizational Citizenship Behavior terhadap Job Performance. Terdapat pengaruh positif dan signifikan Perceived Organizational Support dan Psychological Empowerment terhadap Organizational Citizenship Behavior. Terdapat pengaruh positif dan signifikan Perceived Organizational Support terhadap  Job Performance dimediasi oleh variabel Organizational Citizenship Behavior. Terdapat pengaruh positif dan signifikan Psychological Empowerment terhadap Job Performance dimediasi oleh Organizational Citizenship Behavior.
Perancangan Lemari Pendingin Berbahan Insulasi Musicool-22
Authors: Nugroho Adi , Azharman Zefri , Meldra Delia
Published: February 2024

The purpose of this research is to modify the design of a cooling product and combine it with a new, environmentally friendly insulation that does not harm the ozone layer. In this study, data collection techniques include a literature review from various books and journals. The cooling box in this design uses hydrocarbon refrigerant, namely musicool-22, with polyurethane insulation of 1.75 m thickness and a capacity of 95 kg, resulting in a cooling load of 8768.951 W. A 3HP compressor is used, generating a refrigeration impact of 370 kJ/kg, a refrigerant flow rate of 0.018 kg/s, compressor power of 1080 watts, COP of 6.24, and an estimated cooling time of approximately 1.108 hours.
Implementación de una metodología de diseño básico arquitectónico en la etapa inicial del proceso de aprendizaje del estudiante de arquitectura de la “Universidad Americana - UAM”, 2021-2022
Authors: Rothschuh Dávila Reynalicia , Guerrero Flores Napoléon
Published: February 2024

Encaminados a desarrollar una filosofía, teoría y método de diseño, presentamos este ensayo que recoge la experiencia y los resultados de la implementación de una metodología básica en la enseñanza inicial de la arquitectura, y que hace referencia a los resultados prácticos de los estudiantes del primer curso de la carrera de arquitectura de la Universidad Americana UAM, Nicaragua. El estudio aborda los trabajos presentados en el segundo semestre del año 2021 y los del primer semestre del año 2022, e incluye únicamente aquellos proyectos que obtuvieron los primeros tres lugares en el concurso académico semestral. El cometido principal de este texto es presentar una perspectiva metodológica del desarrollo de los proyectos académicos de las asignaturas iniciales de la disciplina de Diseño Básico Arquitectónico, que sintetiza el aprendizaje de conceptos, propiedades formales, esenciales y principios de la composición arquitectónica; relacionados con la aplicación de los principios de organización espacial y de relaciones estructurales: geométricas, dimensionales y tensionales; aplicando un procedimiento figurativo y una metódica básica de Palabras claves: composición arquitectónica, método de diseño, objeto arquitectónico, prefiguración arquitectónica, procedimiento figurativo, enseñanza del diseño arquitectura diseño. Los estudiantes utilizaron proyecciones ortogonales (vistas frontales, laterales y superior) para crear y ejercitar la composición volumétrica denominada didácticamente como el Modelo Arquitectónico Abstracto Tridimensional (MAAT) 1. Así mismo, en este trabajo se evidencia el crecimiento cognitivo y práctico-aplicativo de los estudiantes, formándose los elementos para el manejo de una filosofía y una teoría propia en esta etapa de aprendizaje, a través de la aplicación de un método de diseño arquitectónico. Los resultados son considerados como satisfactorios, desde la génesis y desarrollo de los proyectos; además de lograr elementos para la apropiación de un estilo proyectual personalizado.
Peringkasan Teks Multi Dokumen Berbahasa Indonesia Menggunakan Sentence Scoring dan SVM
Authors: Fauzi Deri , Abidin Zainal , Fatchurrochman Fatchurrochman
Published: February 2024

Berita online berasal dari berbagai sumber portal berita yang tersedia secara luas di dunia maya. Namun, berita online yang melimpah dapat mengesampingkan detail dan keakuratan berita karena tujuannya untuk memberikan informasi terkini sebanyak mungkin. Ketersediaan berita online di internet dapat menyebabkan penerimaan informasi yang berlebihan, memberikan pemahaman yang kurang jelas mengenai substansi berita tersebut. Oleh karena itu, penting untuk menemukan representasi dokumen berita online guna memahami inti dari berita tersebut. Penelitian ini fokus pada menghasilkan ringkasan berita online multi dokumen dari ekstraksi fitur dan proses klasifikasi menggunakan support vector machine. penelitian ini mengklasifikan berita multi dokumen menggunakan ekstraksi fitur Sentence Scoring dan SVM. Sentence Scoring digunakan untuk input pada metode SVM agar dapat melakukan proses klasifikasi untuk menentukan hasil ringkasan. Hasil pengujian menunjukkan bahwa Fold 3 memberikan hasil terbaik, dengan rata-rata Recall 0.946, Presisi 0.487, dan F-Measure 0.634. ROUGE-1 juga mencapai nilai tertinggi pada Fold 3, yaitu 0.946. Faktor kunci dalam hasil peringkasan adalah proses ekstraksi fitur menggunakan Sentence Scoring dan pelatihan data dengan SVM. Fitur seperti data numerik dan kemiripan antar kalimat berpengaruh signifikan terhadap hasil akhir dari peringkasan.
Sistem Pemantauan dan Klasifikasi Kondisi Lampu dengan Metode Naïve Bayes
Authors: Hidayati Rahmi , Nirmala Irma , Suhardi Suhardi
Published: February 2024

Smarthome adalah sebuah sistem yang telah direncanakan dan dikembangkan dengan tujuan menyederhanakan beragam proses yang terjadi di dalam rumah. Dalam konteks ini, salah satu aspek utama yang diterapkan di rumah pintar adalah pemantauan pencahayaan ruangan. Pencahayaan merupakan faktor kunci dalam kenyamanan dan fungsionalitas kehidupan sehari-hari. Oleh karena itu, peran lampu dalam lingkungan rumah sangat dibutuhkan. Seringkali penghuni rumah cenderung lalai dalam mematikan lampu ketika tidak digunakan, hal ini dapat menyebabkan peningkatan konsumsi energi yang tidak efisien dan pemborosan sumber daya. Untuk mengatasi masalah ini, dibutuhkan teknologi yang mampu memantau dan mengendalikan pencahayaan secara otomatis. Pada penelitian ini, sebuah sistem pemantauan dan klasifikasi kondisi lampu dikembangkan dengan menerapkan metode naïve bayes. Dataset yang digunakan dalam penelitian ini terdiri dari 672 data latih dan 168 data uji. Pengujian dilakukan, dengan confusionmatrix, menghasilkan tingkat accuracy sebesar 98.71%, precision sebesar 98.16%, recall sebesar 98.42%, dan F-1 score sevesar 98.29%. Hasil penelitian ini menunjukkan bahwa metode naïve bayes sangat efektif dalam sistem pemantauan dan klasifikasi kondisi lampu lampu pada ruangan.
Teknik Random Undersampling untuk Mengatasi Ketidakseimbangan Kelas pada CT Scan Kista Ginjal
Authors: Ramadhan Irfan Surya , Salam Abu
Published: February 2024

Kista ginjal adalah pertumbuhan jaringan berbentuk kantong yang berisi carian pada sekitar ginjal. Seringkali kista ginjal tidak menimbulkan gejala, sehingga memerlukan pantauan reguler dokter. Dokter dapat melakukan pemeriksaan dan merencanakan tindakan penelitian lebih lanjut. Penelitiaan ini fokus pada model klasifikasi kista menggunakan model Deep Learning dengan arsitektur Convolution Neural Network (CNN), jenis jaringan syaraf tiruan untuk analisis gambar CT scan kista ginjal. Selain itu, penggunaan teknik pre-processing untuk meningkatkan performa model dengan memperbanyak varisasi data. Dalam membuat model klasifikasi perlu memperhatikan pemahaman data, tingkat interpretabilitas model, dan penanganan overfitting. Overfitting terjadi ketika model terlalu fokus pada data latih, sehingga tidak dapat memproses data uji dengan baik. Solusi untuk menangani masalah distribusi kelas adalah dengan penyeimbang kelas (resampling). Resampling dibagi menjadi dua jenis yaitu, undersampling dan oversampling. Undersampling merupakan metode sampling secara acak memilih di kelas mayoritas dan menambahkannya di kelas minoritas. Dan oversampling merupakan menggandakan sampel di kelas minoritas secara acak. Pada hasil pengujian model yang dilakukan dapat ditarik kesimpulan bahwa penggunaan teknik undersampling RUS memiliki tingkat akurasi tertinggi dengan nilai 30,82% untuk klasifikasi kista ginjal pada dataset tidak seimbang.
Analisa Metasploit Framework “msfvenom” Backdoor Trojan dan Fully Undetected (FUD) Trojan
Authors: Mursalim Mursalim , Darmawan Wachid , Aprilia Tresi
Published: February 2024

Pengunaan teknologi informasi berupa penggunaan internet di Indonesia terus mengalami peningkatan sejak 2 dekade terakhir hingga 73,24% atau 202 juta jiwa dari 275.77 juta jiwa penduduk Indonesia. Penggunaan teknologi tersebut tidak lepas dari sebuah ancaman pengambilan informasi secara ilegal. Tingkat kejahatan cyber berjenis malware mencapai 14.235 serangan hingga bulan april 2023. Pada penelitian ini dilakukan pembuatan malware trojan menggunakan metasploit framework dengan memanfaatkan fungsi msfvenom dan Fully Undetected (FUD) Trojan menggunakan bahasa pemrograman python. Selanjutnya dilakukan pengujian source code FUD Trojan, pengujian keterdeteksian virus melalui virustotal.com. adapun hasil pengujian menunjukkan bahwa keterdeteksian virus paling sedikit yaitu 11 antivirus pada FUD Trojan pada file music.exe, sedangkan keterdeteksian antivirus paling banyak ada pada payload windows.dll sebanyak 56 antivirus. Sedangkan payload.js dan undangan.apk masing masing keterdeteksiannya sebanyak 35 dan 26 antivirus. (FUD) trojan yang memiliki payload FUD malware perlu diwaspadai dikarenakan tidak banyak antivirus yang mendeteksi jenis payload tersebut. jenis virus yang mampu mendeteksi malware tersebut adalah avira dan avg yang secara konsisten mampu mendeteksi 4 malware tersebut
Hearing Loss
Authors: Halstead Jill , Schmid Wolgang
Published: February 2024

In this article we share our personal stories of the loss of a parent during the COVID-19-pandemic. The crisis demonstrated how the medical-scientific apparatus effectively responded to a global health emergency, but also revealed how end of life processes are professionalized in neoliberal societies, where dying and death are outsourced and sanitized, and grieving is increasingly pathologized. Drawing on our backgrounds in music and music therapy, we trace our own experiences of loss to illustrate aspects of our individual and shared bereavement process as it emerged over a 24-month period. We take an intuitive, arts-based, feminist-philosophical approach, where dying and mourning are understood as personal, social, and political events. The article is structured around the presentation of eight poetic fragments from Hearing Loss (Schmid and Halstead, 2023) a co-created digital exhibition on the theme of mourning which includes soundworks, images, narratives, short films, and poems. Through these intimate multi-modal pieces, we reflect how we do loss, and how we might speak about, and listen to, the existential, relational, and transitional experience of losing a loved one in midlife. Our work argues that practices of grieving should be encouraged, shared, and valued to ensure the mournability of every life.
Les dones que beuen vi i mengen carn crua: alteritat femenina en les Bacants d'Eurípides
Authors: Pérez Hurtado Laia
Published: February 2024

En el present article s’analitza la representació de les bacants en l’obra de teatre tràgica homònima, escrita pel dramaturg Eurípides l’any 406 aC. Es busquen les ruptures i transgressions que delimitaven el món de les dones del dels homes, posant de relleu l’alteritat interna amb què es concebia allò femení i l’estudi de les quals ajudarà a esbossar quin era el rol de les dones a l’Atenes del segle V.

The aim of the present work is to analyze the bacchae’s representation in the eponymous tragic play, written at 406 B.C. by the dramatist Euripides. The ruptures and transgressions that delimited the world of women from that of men are sought, highlighting the inner otherness with which femenine was conceived. Their study will help us to sketch the women’s role in fifth-century Athens.
Modeling ferroelectric phase transitions with graph convolutional neural networks
Authors: Ouyang Xin-Jian , Zhang Yan-Xing , Wang Zhi-Long , Zhang Feng , Chen Wei-Jia , Zhuang Yuan , Jie Xiao , Liu Lai-Jun , Wang Da-Wei ,   School of Microelectronics, Faculty of Electronics and Information Engineering, Xi’an Jiaotong University, Xi’an 710049, China,   School of Physics, Henan Normal University, Xinxiang 453007, China,   College of Materials Science and Engineering, Guilin University of Technology, Guilin 541004, China
Published: February 2024

Ferroelectric materials are widely used in functional devices, however, it has been a long-standing issue to achieve convenient and accurate theoretical modeling of them. Herein, a noval approach to modeling ferroelectric materials is proposed by using graph convolutional neural networks (GCNs). In this approach, the potential energy surface of ferroelectric materials is described by GCNs, which then serves as a calculator to conduct large-scale molecular dynamics simulations. Given atomic positions, the well-trained GCN model can provide accurate predictions of the potential energy and atomic forces, with an accuracy reaching up to 1 meV per atom. The accuracy of GCNs is comparable to that of ab inito calculations, while the computing speed is faster than that of ab inito calculations by a few orders. Benefiting from the high accuracy and fast prediction of the GCN model, we further combine it with molecular dynamics simulations to investigate two representative ferroelectric materials—bulk GeTe and CsSnI3, and successfully produce their temperature-dependent structural phase transitions, which are in good agreement with the experimental observations. For GeTe, we observe an unusual negative thermal expansion around the region of its ferroelectric phase transition, which has been reported in previous experiments. For CsSnI3, we correctly obtain the octahedron tilting patterns associated with its phase transition sequence. These results demonstrate the accuracy and reliability of GCNs in the modeling of potential energy surfaces for ferroelectric materials, thus providing a universal approach for investigating them theoretically.
Developmental patterning function of GNOM ARF-GEF mediated from the cell periphery
Authors: Adamowski Maciek , Matijević Ivana , Friml Jiří
Published: February 2024

The GNOM (GN) Guanine nucleotide Exchange Factor for ARF small GTPases (ARF-GEF) is among the best studied trafficking regulators in plants, playing crucial and unique developmental roles in patterning and polarity. The current models place GN at the Golgi apparatus (GA), where it mediates secretion/recycling, and at the plasma membrane (PM) presumably contributing to clathrin-mediated endocytosis (CME). The mechanistic basis of the developmental function of GN, distinct from the other ARF-GEFs including its closest homologue GNOM-LIKE1 (GNL1), remains elusive. Insights from this study largely extend the current notions of GN function. We show that GN, but not GNL1, localizes to the cell periphery at long-lived structures distinct from clathrin-coated pits, while CME and secretion proceed normally in gn knockouts. The functional GN mutant variant GNfewerroots, absent from the GA, suggests that the cell periphery is the major site of GN action responsible for its developmental function. Following inhibition by Brefeldin A, GN, but not GNL1, relocates to the PM likely on exocytic vesicles, suggesting selective molecular associations en route to the cell periphery. A study of GN-GNL1 chimeric ARF-GEFs indicates that all GN domains contribute to the specific GN function in a partially redundant manner. Together, this study offers significant steps toward the elucidation of the mechanism underlying unique cellular and development functions of GNOM.
Sexual coordination in a whole-brain map of prairie vole pair bonding
Authors: Gustison Morgan L , Muñoz-Castañeda Rodrigo , Osten Pavel , Phelps Steven M
Published: February 2024

Sexual bonds are central to the social lives of many species, including humans, and monogamous prairie voles have become the predominant model for investigating such attachments. We developed an automated whole-brain mapping pipeline to identify brain circuits underlying pair-bonding behavior. We identified bonding-related c-Fos induction in 68 brain regions clustered in seven major brain-wide neuronal circuits. These circuits include known regulators of bonding, such as the bed nucleus of the stria terminalis, paraventricular hypothalamus, ventral pallidum, and prefrontal cortex. They also include brain regions previously unknown to shape bonding, such as ventromedial hypothalamus, medial preoptic area, and the medial amygdala, but that play essential roles in bonding-relevant processes, such as sexual behavior, social reward, and territorial aggression. Contrary to some hypotheses, we found that circuits active during mating and bonding were largely sexually monomorphic. Moreover, c-Fos induction across regions was strikingly consistent between members of a pair, with activity best predicted by rates of ejaculation. A novel cluster of regions centered in the amygdala remained coordinated after bonds had formed, suggesting novel substrates for bond maintenance. Our tools and results provide an unprecedented resource for elucidating the networks that translate sexual experience into an enduring bond.
Epistasis between mutator alleles contributes to germline mutation spectrum variability in laboratory mice
Authors: Sasani Thomas A , Quinlan Aaron R , Harris Kelley
Published: February 2024

Maintaining germline genome integrity is essential and enormously complex. Although many proteins are involved in DNA replication, proofreading, and repair, mutator alleles have largely eluded detection in mammals. DNA replication and repair proteins often recognize sequence motifs or excise lesions at specific nucleotides. Thus, we might expect that the spectrum of de novo mutations – the frequencies of C>T, A>G, etc. – will differ between genomes that harbor either a mutator or wild-type allele. Previously, we used quantitative trait locus mapping to discover candidate mutator alleles in the DNA repair gene Mutyh that increased the C>A germline mutation rate in a family of inbred mice known as the BXDs (Sasani et al., 2022, Ashbrook et al., 2021). In this study we developed a new method to detect alleles associated with mutation spectrum variation and applied it to mutation data from the BXDs. We discovered an additional C>A mutator locus on chromosome 6 that overlaps Ogg1, a DNA glycosylase involved in the same base-excision repair network as Mutyh (David et al., 2007). Its effect depends on the presence of a mutator allele near Mutyh, and BXDs with mutator alleles at both loci have greater numbers of C>A mutations than those with mutator alleles at either locus alone. Our new methods for analyzing mutation spectra reveal evidence of epistasis between germline mutator alleles and may be applicable to mutation data from humans and other model organisms.
Proteomic study on nintedanib in gastric cancer cells
Authors: Dong Xiaohua , Wang Liuli , Wang Da , Yu Miao , Yang Xiao jun , Cai Hui
Published: February 2024

Background

Gastric cancer is a very common gastrointestinal tumor with a high mortality rate. Nintedanib has been shown to significantly reduce tumor cell proliferation and increase apoptosis in gastric cancer cells in vitro. However, its systemic action mechanism on gastric cancer cells remains unclear. A high-throughput proteomic approach should help identify the potential mechanisms and targets of nintedanib on gastric cancer cells.

Methods

The effects of nintedanib on the biological behavior of gastric cancer cells were evaluated. A cytotoxic proliferation assay was performed to estimate the half maximal inhibitory concentration (IC50). AGS cells were divided into control, and nintedanib-treated groups (5 µM, 48 h), and differential protein expression was investigated using tandem mass tags (TMT) proteomics. The molecular mechanisms of these differentially expressed proteins and their network interactions were then analyzed using bioinformatics, and potential nintedanib targets were identified.

Results

This study identified 845 differentially expressed proteins in the nintedanib-treated group (compared to the control group), comprising 526 up-regulated and 319 down-regulated proteins. Bioinformatics analysis revealed that the differentially expressed proteins were primarily enriched in biological pathways for branched-chain amino acid metabolism, steroid biosynthesis, propionate metabolism, fatty acid metabolism, lysosome, peroxisome, and ferroptosis. Key driver analysis revealed that proteins, such as enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase (EHHADH), isocitrate dehydrogenase 1 (IDH1), acyl-CoA oxidase 1 (ACOX1), acyl-CoA oxidase 2 (ACOX2), acyl-CoA oxidase 3 (ACOX3), and acetyl-CoA acyltransferase 1 (ACAA1) could be linked with nintedanib action.

Conclusion

Nintedanib inhibits the proliferation, invasion, and metastasis of gastric cancer cells. The crossover pathways and protein networks predicted by proteomics should provide more detailed molecular information enabling the use of nintedanib against gastric cancer.
Inconsistent effects of components as evidence for non-compositionality in chimpanzee face-gesture combinations? A response to Oña et al (2019)
Authors: Cauté Maxime , Chemla Emmanuel , Schlenker Philippe
Published: February 2024

Using field observations from a sanctuary, Oña and colleagues (DOI: 10.7717/peerj.7623) investigated the semantics of face-gesture combinations in chimpanzees (Pan troglodytes). The response of the animals to these signals was encoded as a binary measure: positive interactions such as approaching or grooming were considered affiliative; ignoring or attacking was considered non-affiliative. The relevant signals are illustrated in Fig. 1 (https://doi.org/10.7717/peerj.7623/fig-1), together with the outcome in terms of average affiliativeness. The authors observe that there seems to be no systematicity in the way the faces modify the responses to the gestures, sometimes reducing affiliativeness, sometimes increasing it. A strong interpretation of this result would be that the meaning of a gesture-face combination cannot be derived from the meaning of the gesture and the meaning of the face, that is, the interpretation of chimpanzees’ face-gesture combinations are non compositional in nature. We will revisit this conclusion: we will exhibit simple compositional systems which, after all, may be plausible. At the methodological level, we argue that it is critical to lay out the theoretical options explicitly for a complete comparison of their pros and cons.
Arthrological reconstructions of the pterosaur neck and their implications for the cervical position at rest
Authors: Buchmann Richard , Rodrigues Taissa
Published: February 2024

The lack of any pterosaur living descendants creates gaps in the knowledge of the biology of this group, including its cervical biomechanics, which makes it difficult to understand their posture and life habits. To mitigate part of this issue, we reconstructed the cervical osteology and arthrology of three pterosaurs, allowing us to make inferences about the position of the neck of these animals at rest. We used scans of three-dimensionally preserved cervical series of Anhanguera piscator, Azhdarcho lancicollis and Rhamphorhynchus muensteri for the reconstructions, thus representing different lineages. For the recognition of ligaments, joint cartilages, and levels of overlapping of the zygapophyses, we applied the Extant Phylogenetic Bracket method, based on various extant birds and on Caiman latirostris. We inferred that pterosaur intervertebral joints were probably covered by a thin layer of synovial cartilage whose thickness varied along the neck, being thicker in the posterior region. Ignoring this cartilage can affect reconstructions. According to the vertebral angulation, their neck was slightly sinuous when in rest position. Our analyses also indicate that pterosaurs had segmented and supra-segmented articular cervical ligaments, which could confer stabilization, execute passive forces on the neck and store elastic energy.
Organic fertilizer type and dose affect growth, morphological and physiological parameters, and mineral nutrition of watermelon seedlings
Authors: Zhang Qianwen , Masabni Joseph , Niu Genhua
Published: February 2024

Background

Organic agriculture has grown rapidly in recent years due to its environmental friendliness, sustainability, and improved farm profitability. Transplants are commonly used for fruits and vegetables to achieve consistent quality, uniformity, and easy field spacing control. The efficacy and optimal amounts of fertilizers for organic transplant production need to be investigated.

Methods

The effects of three organic fertilizers (Sustane 4-6-4, Nature Safe 7-7-7, and Dramatic 2-4-1) and one conventional fertilizer Peters Professional 20-20-20 (Conventional) with four doses (nitrogen (N) content was matched among fertilizers in each level, as 0.14 g/L, 0.28 g/L, 0.56 g/L, and 0.84 g/L N, respectively) on watermelon seedlings were compared in this study.

Results

The results showed that all organic fertilizer treatments were not significantly different from the Conventional group in terms of watermelon germination. The only exception was the highest dose of Sustane 4-6-4 (0.84 g/L N) which decreased the germination rate and relative emergence index. Generally, growth index, shoot fresh and dry weights, true leaf number, and stem diameter increased as the amount of N increased within each fertilizer type. The best shoot growth was observed in the highest doses of Conventional and Dramatic 2-4-1 treatments (0.84 g/L N). However, Dramatic 2-4-1 treatments resulted in the lowest root growth when compared to other fertilizers at the same N dose. The second highest fertilization dose (0.56 g/L N) of Sustane 4-6-4 had the best root growth according to root fresh weight, root volume, root area, total root length, as well as the numbers of root tip and crossing when compared to other treatments. For seedlings, a well-developed root system can ensure a good seedling establishment and high survival rate under stressful field conditions after transplanting. Thus, Sustane 4-6-4 at 14 g/L (0.56 g/L N) is recommended to produce high-quality organic watermelon seedlings among the treatments applied in this study.
Biological and growth parameters of Plotosus lineatus in the Mediterranean Sea
Authors: Doğdu Servet Ahmet , Turan Cemal
Published: February 2024

This study examined the age distribution and growth characteristics of the striped eel catfish (Plotosus lineatus), which is an invasive alien species in the eastern Mediterranean. A total of 1,011 samples were collected from Iskenderun Bay (Turkey), with lengths ranging from 5.1 to 16.8 cm, predominantly comprising females (1:1.92). Age 3 represented the majority in the population (52.03%). The value of the scaling exponent “b” of the length-weight relationship was less than “3” for both sexes (females: 2.28; males: 2.26; combined: 2.27). The results for the von Bertalanffy growth parameters were observed for the combined sexes as, L∞ = 24.9934 cm, k = 0.1718 year−1, and t₀ = −1.7707 years. The striped eel catfish populations in Iskenderun Bay exhibited negative allometric growth patterns and were predominantly composed of adult individuals. This study presents the dataset on the length-weight correlations, age-growth characteristics, and von Bertalanffy growth parameters of Plotosus lineatus in the Mediterranean Sea, thereby significantly contributing to comprehending the stock dynamics. It is anticipated that this study will make a significant contribution to the management of P. lineatus stocks, given its invasive nature.