bluuebunny/crossref_metadata_2025 huggingface dataset:
Vitrectomy for Macular Hole with Macular Foveoschisis in Myopic Tractional Maculopathy PPV for MH-MFS
Authors:   IMO – Instituto de Microcirugía Ocular, Barcelona, Spain, G Rodríguez-Vargas , F Ortiz-Coto ,   IMO – Instituto de Microcirugía Ocular, Barcelona, Spain, Jelstrup Burés ,   IMO – Instituto de Microcirugía Ocular, Barcelona, Spain, C Mateo ,   IMO – Instituto de Microcirugía Ocular, Barcelona, Spain
Published: March 2024

Background: Macular Hole with Macular Foveoschisis (MH-MFS) represents one of the end stages of Myopic Traction Maculopathy (MTM). This study demonstrates the effectiveness of Pars Plana Vitrectomy (PPV) with appropriate Internal Limiting Membrane (ILM) peeling and use of an ILM flap without the conventional use of macular buckle for resolving this condition. Methods: Twelve highly myopic eyes with MH-MFS underwent PPV in a single institution. Careful fovea sparing Inner Limiting Membrane (ILM) peeling with inverted flap under repeated re-staining with brilliant blue was performed. Best Corrected Visual Acuity (BCVA) and rate of Macular Hole (MH) closure, as measured by Optic Coherence Tomography. Results: Primary MH closure was obtained in 90.9% of the cases. Best Corrected Visual Acuity (BCVA) improved in 9 patients (75%) from a baseline BCVA of 0.59 ± 0.26 log MAR (20/77) to a post-operatory BCVA of 0.35 ± 0.25 log MAR (20/44) with statistical significance (p=0.004). Foveoschisis resolution occurred as follows: 6 cases within the first month, and 9 cases by the first year. Partial resolution was achieved in 2 cases, while one failed to resolve during follow-up. Conclusions: PPV with ILM peeling and inverted flap is a safe and effective method for managing MH-MFS. Careful identification of ILM and a thorough understanding of the vitreomacular interface abnormalities is key to surgical success.
The Approach to Diagnosis and Management of Corneal Ulcers
Authors:   Department of Ophthalmology, Optometrists Association of Kenya, Kenya, B Mark
Published: March 2024

Corneal ulcers are among the major causes of corneal blindness. The cause of corneal ulceration is a variety of infections. The key to improving clinical and visual results in cases of corneal ulcers is an accurate, speedy diagnosis and rapid treatment. However, there are no established standards or guidelines for treating corneal ulcers. Even seasoned eye care professionals occasionally have trouble predicting how the disease will progress in most patients. This article makes an effort to offer a general overview of the diagnosis process and treatment plan for a corneal ulcer.
Special Herpetic Keratitis
Authors:   Department of Ophthalmology B, Ibn-Sina University Hospital, Rabat, Morocco, A Bouslamti , K Majdoubi ,   Department of Ophthalmology B, Ibn-Sina University Hospital, Rabat, Morocco, I Hasnaoui ,   Department of Ophthalmology B, Ibn-Sina University Hospital, Rabat, Morocco, C Bardi ,   Department of Ophthalmology B, Ibn-Sina University Hospital, Rabat, Morocco, B Anas ,   Department of Ophthalmology B, Ibn-Sina University Hospital, Rabat, Morocco, L Serghini ,   Department of Ophthalmology B, Ibn-Sina University Hospital, Rabat, Morocco, A Elhassan ,   Department of Ophthalmology B, Ibn-Sina University Hospital, Rabat, Morocco, A Berraho ,   Department of Ophthalmology B, Ibn-Sina University Hospital, Rabat, Morocco
Published: March 2024

Herpetic keratitis a common form of eye infection. Its manifestations can often impede the quality of life and vision. We report the case of a 32 year old female with a unilateral typical herpetic keratitis. A treatment with topical antivirals gave great results. The surveillance of recurrences is primordial in these cases.
Template-dependent DNA ligation for the synthesis of modified oligonucleotides
Authors: Sabat Nazarii , Stämpfli Andreas , Hanlon Steven , Bisagni Serena , Sladojevich Filippo , Püntener Kurt , Hollenstein Marcel
Published: March 2024

Chemical modification of DNA is a common strategy to improve the properties of oligonucleotides, particularly for therapeutics and nanotechnology. Existing synthetic methods essentially rely on phosphoramidite chemistry or the polymerization of nucleoside triphosphates but are limited in terms of size, scalability, and sustainability. Herein, we report a robust alternative method for the de novo synthesis of modified oligonucleotides using template-dependent DNA ligation of shortmer fragments. Our approach is based on the fast and scaled accessibility of chemically modified shortmer monophosphates as substrates for the T3 DNA ligase. This method has shown high tolerance to chemical modifications, flexibility and overall efficiency, thereby granting access to an ultimately broad range of modified oligonucleotides of different lengths (20 → 120 nucleotides). We have applied this method to the synthesis of clinically relevant antisense drugs and diversely modified ultramers. Furthermore, the designed chemoenzymatic approach has great potential for diverse applications in therapeutics and biotechnology.
Aggregation of N-Heteropolycyclic Aromatic Molecules: The Acridine Dimer and Trimer
Authors: Himmel Hans-Jörg , Germer Stefan , Bauer Marco , Hübner Olaf , Dreuw Andreas
Published: March 2024

Polycyclic aromatic hydrocarbons and their nitrogen-substituted analogues are of great interest for various applications in organic electronics. The performance of such devices is determined not only by the properties of the single molecules, but also by the structure of their aggregates, which often form via self-aggregation. Gaining insight into such aggregation processes is a challenging task, but crucial for a fine-tuning of the materials properties. In this work, an efficient approach for the generation and characterisation of aggregates is described, based on matrix-isolation experiments and quantum-chemical calculations. This approach is exemplified for aggregation of acridine. The acridine dimer and trimer are thoroughly analysed on the basis of matrix-isolation spectroscopy over two spectral ranges and quantum chemical calculations, which agree well with each other. Thereby a novel structure of the acridine dimer is found, which disagrees with a previously reported one. In addition, a structure of the trimer is determined and new insight into the photophysics of small acridine aggregates is gained. Finally, an outlook is given on how even higher aggregates can be made accessible through experiment.
Self-assembly of Tyrosine-containing Peptides into Injectable Hydrogels with Distinct Nanostructures is Key in Determining Inflammatory Response of Macrophages
Authors: Wychowaniec Jacek K. , Bektas Ezgi Irem , Vernengo Andrea J. , Mürner Marcia , Airoldi Marielle , Edwards-Gayle Charlotte J.C. , Tipay Paul Sean , Sapudom Jiranuwat , Teo Jeremy , Eglin David , D'Este Matteo
Published: March 2024

Self-assembling peptides (SAPs) are fully defined nanobiomaterials offering unprecedented opportunities to control nanostructure and chemical attributes to investigate and manipulate cellular signals. To investigate the influence of chemical and morphological characteristics on inflammatory signalling in native immunity, we designed five beta-sheet SAPs: EFEFKFEFK (EF8), YEFEFKFEFK (YEF8), YEFEFKFEFK (EF8Y), YEFEFKFEFK (YEF8Y) and EYEFKFEFK (EYF8) (F: phenylalanine; E: glutamic acid; K: lysine, Y: tyrosine). The position of tyrosine in the peptide sequence dictated the distinct self-assembly into nanostructures, with sequences EF8Y, YEF8Y, EYF8 self-assembling into thin nanofibers d≈3.8 ± 0.2 nm, YEF8 self-assembling into rod-like flat ribbons d>20 nm and EF8 (control) consisting of both types of self-assembled nanostructures. These distinct nanostructures induced contrasting inflammatory response of monocytic model THP-1 cells-derived macrophages (MΦs). Presence of soluble EF8 nanofibers (at 2 mM) induced anti-inflammatory response and polarization towards an M2 state, whereas YEF8 displayed tendency for inducing pro-inflammatory response and polarization towards M1 state. The EF8Y, YEF8Y, EYF8 SAPs did not induce an inflammatory response in our models. These results were validated using peripheral blood mononuclear cells (PBMCs)-derived MΦs from human donors, confirming the critical role of the EF8 and YEF8 SAPs as possible orchestrators of the repair of tissues or inducers of pro-inflammatory state, respectively. These findings will facilitate the utilization of this family of SAPs as immunomodulatory nanobiomaterials potentially changing the course of inflammation during the progression of various diseases.
A simple model for the Pauli Repulsion with possible utility in QM, MM and Chemical Education
Authors: PEETERS JORDY , Vanommeslaeghe Kenno
Published: March 2024

The Pauli repulsion is the intermolecular force responsible for the volume and low compressibility of condensed-phase matter at normal conditions. A simple model for this force is presented, in which per-atom electron densities are represented as spherical charge distributions that are prevented from significantly overlapping. In the example of two noble gas atoms approaching one another beyond their van der Waals radii, the distance between the centers of the electronic charge distributions becomes larger than the distance between the nuclei, giving rise to an unfavorable electrostatic interaction. For the purpose of calculating this interaction, the model is further simplified by representing the per-atom electron density as a negative point charge, inspired by the classical Drude oscillator. The dispersion interaction is simplified to an R^-6term, centered on the aforementioned point charges. Despite the gross simplicity of the resulting formalism, near-quantitative agreement with high-level QM interaction energies of noble gas dimers is achieved. Accordingly, the present model is thought to have utility in force fields, in post-HF and post-DFT dispersion corrections and in chemical education.
Natural Fragment Bond Orbital Method for Inter-Fragment Covalent Interaction Analysis
Authors: ZHANG Yichi , Sheong Fu Kit , Lin Zhenyang
Published: March 2024

We report the natural fragment bond orbital (NFBO) method for inter-fragment covalent interaction analysis, as an extension to the well-known natural bond orbital method. NFBOs together with their corresponding natural fragment hybrid orbitals (NFHOs) can be used to highlight the local covalent bonding and anti-bonding among fragments out of the delocalized canonical molecular orbitals, from ordinary localized two-fragment bonds to delocalized multi-fragment ones. In this paper, we provide the algorithm for finding NFBOs and showcase its usage with several chemically interesting systems featuring significant inter-fragment covalent interaction. This paper also includes discussion on the relationship and differences between the NFBO method and other methods which serve similar purposes. With examples and comparisons, the NFBO method is shown to be a powerful tool with which to analyze molecules possessing strong inter-fragment covalent interaction.
Markovnikov Selective Hydroboration of Aryl Alkenes Catalyzed by Quaternary Ammonium Salts
Authors: Huninik Paweł , Im Hoyoung , Szyling Jakub , Baik Mu-Hyun , Walkowiak Jędrzej
Published: March 2024

Despite recent advancements in the development of catalytic Markovnikov-selective hydroboration of alkenes, the metal-free procedure has long remained an unsolved challenge. Here, we report an organocatalytic Markovnikov-selective hy-droboration of aryl alkenes using a commercially available quaternary ammonium catalyst. The method is operationally simple, scalable, and compatible with a wide variety of substrates and it can be successfully applied in the synthesis of active pharmaceutical ingredients (API) such as Chlorphenoxamine. Through in-depth experimental and DFT studies, we elucidate a nuanced understanding of the mechanism and regioselectivity of this reaction.
Prognostic Self-Esteem of the Results of Personality Activity in a Difficult Situation: to the Question of the Definition
Authors:   Izhevsk State Medical Academy of the Ministry of Health of the Russian Federation, Zhuchenko O. A.
Published: March 2024

The article presents a complex study of prognotic self-esteem of the results of pesonality activities in a difficult situation. Due to an increasing number of stress inducing situations the need for new resources helping to enhance stress resistance has become acute. The article attempts at analysing the structure of prognostic self-esteem of the results of pesonality activities in a difficult situation (the case of stress at an exam), its definition has been introduced into the scholarly discourse. The study has revealed that the components of prognostic self-esteem of the results of pesonality activities in a difficult situation are motivational (a desired result), cognitive (an expected result), and affective and cognitive (subjective evaluation of activity results) componets. The study contributes to the comprehension of the issue of the search for resources of personality stress resistance.
Attributes of Mental and Speech Development of Young Orphaned Children
Authors:   Irkutsk State University, Serebrennikova S. Y. , Sokolova I. О. ,   Irkutsk State University
Published: March 2024

The purpose of this work is to describe the specifics of the psycho-speech development of orphans of early age. The article summarizes some current information on the development of deprived children of early and preschool age. The data of studying the mental and speech development of orphans aged 3 and 4 are presented. The criteria for evaluating the results and the factors determining the speech and mental status of children aged 3 and 4 are indicated. Quantitative indicators of the formation of different components of children's speech are summarized and their differences in the selected groups are noted. The characteristics of the speech of children of different levels are described in detail; the general trends of their psycho-sheech development at an early age are outlined; recommendations for correctional speech therapy work are formulated taking into account the real speech status of children. The main provisions and conclusions of the study contribute to the content of correctional work with children in the conditions of the orphanage.
Pneumatické pružné hriadeľové spojky v pohonoch mechanických sústav
Authors:   University of Žilina, Kaššay Peter , Urbanský Matej
Published: March 2024

The article presents a newly developed pneumatic flexible shaft coupling with hose flexible element usable, among other applications, in drives of mechanical systems. The presented coupling uses a hose-shaped flexible element winding between the supporting surfaces of coupling’s driving and driven hub. As the torque transfer is ensured with compressed air, the torsional stiffness of coupling can be adapted to actual operating parameters (rotational speed) with change or air pressure inside the flexible elements. This makes the presented coupling suitable for semi-active torsional vibration control. A patent was also granted for the presented coupling design. The design of hose-shaped element enables reliable sealing of compression volume and it is also easy to assembly and dismantle.
Možnosti využitia technológie termálneho vŕtania na účely spájania tenkostenných nerovnakých materiálov v automobilovom priemysle
Authors:   University of Žilina, Guzanová Anna , Veligotskyi Nikita , Draganovská Dagmar
Published: March 2024

The article deals with the study of the applicability of flowdrill technology for the formation of joints between thin metallic materials based on iron and aluminium alloy. This technology is primarily used to create holes in profiles with a local increase in material thickness to accommodate a greater number of threads. If used to drill two interleaved thin-walled materials, a joint is formed as a secondary effect. The quality of the resulting bushings forming the interference fit joint was investigated. The joints were formed using a combination of uncoated deep drawn steel, galvanized HSLA steel and aluminum alloy, in different positions in the joint. Subsequently, tensile shear testing of single joints was performed. The load carrying capacity of the joints was also tested in combination with adhesive bonding. The load capacity of the joints combined with bonding was significantly higher compared to flowdrill joints. The combination of both technologies yields an increase in the absorbed energy of the joint at failure.
Magnetic forming with heat in a magnetic field
Authors:   University of Žilina, Moravec Ján
Published: March 2024

The article focuses on the application of a magnetic field in the forming of low-carbon steel castings. The original solution of the forming device, which was used in the experimental works, is presented. The results of the experimental works confirmed the suitability of its use for the mentioned work.
Vyladenie mechanickej sústavy pohonu piestového kompresora z hľadiska veľkosti torzného kmitania
Authors:   University of Žilina, Urbanský Matej , Kaššay Peter
Published: March 2024

One of possible ways to change the amount of compressed air delivered by a piston compressor is to change its operating speed. However, it can cause an improper tuning of the mechanical system of piston compressor drive in terms of torsional dynamics. In order to avoid excessive torsional vibration, a suitable pneumatic flexible shaft coupling can be used in the system. An optimum air pressure value in a pneumatic coupling was determined experimentally for three various operating modes of an experimental mechanical system of piston compressor drive.
Návrh koľajového adaptéra typu guma-koľajnica pre ľahké nákladné vozidlo
Authors:   University of Žilina, Dižo Ján , Fiačan Jakub , Blatnický Miroslav , Lovska Alyona , Ishchuk Vadym
Published: March 2024

The article is focused on design of a tyre-rail adapter to be mounted on a light road-rail vehicle. The novelty of the design consists in its possibility to change the wheelbase of the vehicle axles for different railway tracks gauges. Then, the considered light vehicle could fulfil various working tasks in a country, where more railway tracks gauges occur. The modified vehicle is a light lorry, which is intended to be used as a versatile and utility vehicle for maintenance purposes and repairing purposes.
Materiály s vysokou teplotou tavenia využívané v práškovej metalurgii
Authors:   University of Žilina, Kantoríková Elena
Published: March 2024

Metals with a high melting point are frequently used materials in technical practice. Their fundamental advantage over other metal materials is their higher melting temperature, which exceeds the melting temperature of iron. Thanks to this physical property, such metals and their alloys can be used in environments where the components are subject to high thermal stress.
Vplyv tvaru telesa na deformáciu čelného ozubenia
Authors:   University of Žilina, Maláková Silvia , Kepeň Harachová Daniela , Krajňák Jozef
Published: March 2024

The article is devoted to the analysis of the influence of the basic parameters of the body of the spur gear on the deformation of the teeth in meshing. The problem is solved for spur gears of large dimensions, the semi finished product of which can be a weldment, casting or forging. Gear deformations are determined by the finite element method. Examples of simulation and subsequent processing of the results demonstrate the extent of the influence of individual parameters of the gear body on the deformation of the gearing. At the same time, the results point to suitable designs of shape and dimensions to achieve the desired deformation of the teeth but with the smallest possible weight of the gears.
The Procedure of Morality
Authors: Herstein Ori , Malcai Ofer
Published: March 2024

Does morality have a procedure? Unlike law, morality is arguably neither posited nor institutional. Thus, while morality undeniably prescribes various procedures, that morality itself has a procedure is less obvious. Indeed, the coexistence of procedural moral norms alongside substantive moral norms might seem paradoxical, given that they often yield contradictory prescriptions. After all, one may wonder, is morality not substantive all the way down? Nevertheless, the paper argues that morality has a “procedural branch” containing numerous norms that are themselves procedural. These norms comprise what we hold are the three hallmarks of a procedural norm: second-orderness, providing reasons on how to engage with other norms, and outcome-neutrality. In this respect, morality is more like law than what one might have expected.
Forgiveness and Negative Partiality
Authors: Brandt Joshua
Published: March 2024

Forgiveness has traditionally been characterized an affective response to a wrongdoing, i.e. a psychological process that involves ridding oneself of resentment or other negative reactive attitudes. In contrast to the prevailing model, this paper advocates for the emerging position that forgiveness should be understood as a normative power akin to a promise. In particular, I argue that forgiveness involves surrendering the right to discount the interests of a perpetrator (a special permission the victim acquires in virtue of having been wronged). I argue that this model fits and/or explains important features of forgiveness, such as the idea that forgiveness is a personal response to a blameworthy wrong, that forgiveness re-establishes a relation of equality, and that forgiveness is ‘normatively significant’. I further develop the position by showing how it can provide a unified case of paradigmatic forgiveness, self-forgiveness, and third-party forgiveness—this explanatory power distinguishes the view from previous articulations of the idea that forgiveness is a normative power. The final section further explores these distinctions by delimiting the scope of forgiveness to exclude powers related to apologies, compensation, or ‘redemption’.
Weakness of Political Will
Authors: Hernandez Flowerman Camila
Published: March 2024

In this paper I provide a preliminary account of weakness of political will (political akrasia). My aim is to use theories from the weakness of will literature as a guide to develop a model of the same phenomenon as it occurs in collective agents. Though the account will parallel the traditional view of weakness of will in individuals, weakness of political will is a distinctly political concept that will apply to group agents such as governments, institutional actors, and other political collectives. I further argue that blaming inaction by collective political agents on a “lack of political will” should be understood as blaming a kind of akratic break within the deliberative process, leading to an inability of the collective agent to capitalize on existing group attitudes in order to translate them into policy or legislation. My primary example throughout will be U.S. political inaction with respect to the climate crisis.
Clinical Observation of Chinese Medicinal Prescriptions for Swelling and Pain in The Postoperative Treatment of Mixed Hemorrhoids
Authors: Duan Yuru , Xu Guangliang , Ge Lei , Zhang Wei , Zhang Xu , Yang Yi
Published: March 2024

Objective: To observe the clinical effect of traditional Chinese medicine (TCM) on reducing swelling and pain in patients with mixed hemorrhoids. Methods: Sixty patients with mixed hemorrhoids who were admitted to the Hospital of Traditional Chinese Medicine of Qiqihar from January 2023 to January 2024 were selected and divided into two groups. The treatment group (n = 30) was treated with mixed hemorrhoid ligation combined with traditional Chinese swelling and pain medicine, and the control group (n = 30) was only treated with mixed hemorrhoid ligation. The pain level, edema score, and prognosis of the two groups after the intervention were analyzed. The clinical efficacy was used as the evaluation criterion to compare the clinical effects of different treatment options. Results: After the treatment, the pain score, edema score, and prognostic wound score of the treatment group were all lower than those of the control group (P < 0.05). The total clinical effectiveness of the treatment group (100%) was higher than that of the control group (76.67%), (χ2 = 4.2857, P < 0.05). Conclusion: The application of traditional Chinese swelling and pain medicine in treating patients with mixed hemorrhoids effectively reduced the patient’s pain, reduced the degree of wound edema, promoted wound healing, and improved the patient’s prognosis. The curative effect was significant and had a positive impact.
СУЩНОСТЬ, СОДЕРЖАНИЕ И ОСОБЕННОСТИ ИННОВАЦИОННОЙ ПОЛИТИКИ ПРЕДПРИЯТИЯ
Authors: ШАТСКАЯ АЛИНА АЛЕКСАНДРОВНА
Published: March 2024

В эпоху бурных технологических преобразований, решающую роль в достижении успеха и удержании конкурентных позиций предприятий занимает их способность к своевременному внедрению инноваций. Грамотное управление инновациями не только способствует устойчивости предприятия перед лицом рыночных вызовов, но и зачастую выдвигает их в роли пионеров отраслевых новшеств. Настоящая статья представляет собой всесторонний анализ инновационной политики предприятий. Мы уделили особое внимание детальному изучению процессов создания и реализации инновационной политики, а также рассмотрели управленческие аспекты инноваций на разных уровнях. Инновационная политика организации, характеризующаяся сложностью и многоаспектностью, требует всестороннего подхода к анализу её элементов - от формирования стратегического видения до оценки эффективности отдельных инновационных проектов. Актуальность этого исследования подчёркивается постоянными колебаниями в экономической среде, которые вынуждают предприятия быть гибкими и открытыми к инновациям. Цель данного исследования - осветить критические аспекты и уникальные особенности инновационной политики предприятий, выделить ключевые направления для совершенствования этого процесса в контексте долгосрочной жизнеспособности бизнеса.
DAMPAK ERA â€˜NEW NORMALâ€™ TERHADAP TIMBULAN DAN KOMPOSISI SAMPAH DI GEDUNG PERKULIAHAN PERGURUAN TINGGI: STUDI KASUS GEDUNG S FTUI
Authors: Defiana Fifi , Dewi Ova Candra , Panjaitan Toga , Widyarko Widyarko , Sulistiani Coriesta Dian
Published: March 2024

AbstrakGedung dan komplek perguruan tinggi hingga kini masih mengelola sampahnya dengan menggunakan sistem kumpul, angkut dan buang. Namun, dengan merebaknya wabah COVID-19 yang lalu ikut juga menghentikan kegiatan perkuliahan pada gedung-gedung perguruan tinggi. Namun sejak wabah COVID-19 mulai dapat dikendalikan, seluruh kegiatan kembali berjalan dengan skenario â€˜new normalâ€™. Perubahan pola penggunaan gedung selama masa â€˜new normalâ€™ berpotensi juga mempengaruhi timbulan dan komposisi sampah yang dihasilkan. Untuk itu, penelitian ini bertujuan untuk mengkaji perbandingan jumlah timbulan dan komposisi sampah pada gedung kuliah saat sebelum pandemi COVID-19 dan pada era â€˜new normalâ€™. Metode penelitian menggunakan mixed methods, dengan studi kasus menggunakan gedung S yang merupakan gedung perkuliahan umum yang belokasi di FTUI, Kota Depok. Penelitian ini menunjukkan bahwa jumlah mahasiswa yang hadir pada era â€˜new normalâ€™ hanya 57,6% dari mahasiswa yang terdaftar, namun timbulan sampah yang dihasilkan sebesar 81,44 kg/hari, atau sebesar 0,04 kg/hari/mahasiswa atau dua kali lebih banyak dari sebelum pandemi COVID-19, dengan komposisi sampah 61,40% adalah sisa makanan dan kemasan makanan dan 38,60% adalah sampah plastik. Hal tersebut karena adanya perubahan gaya hidup sebagian besar mahasiswa. Bertambahnya timbulan sampah saat â€˜new normalâ€™, membuat pengelolaan sampah pada Gedung S perlu disesuaikan kembali dengan komposisi sampah yang dihasilkan, dengan menerapkan konsep 3R.Kata kunci: Pengolahan sampah, gedung kuliah, era â€˜new normalâ€™AbstractBuildings and university complexes still manage their waste using a collection, transport and disposal system. The recent outbreak of the COVID-19 outbreak also stopped lecture activities in university buildings. However, since the COVID-19 outbreak began to be controlled, all activities have resumed with a 'new normal' scenario. The amount and makeup of waste generated are impacted by this change. This research aims to examine the comparison of the amount of waste generation and composition in lecture buildings before the COVID-19 pandemic and in the 'new normal' era. The research uses mixed methods, with a case study using S Building, a public lecture building located at FTUI, Depok. This research shows that the number of students attending in the 'new normal' era was only 57.6% of registered students, but the waste generated was 81.44 kg/day, or 0.04 kg/day/student, twice more than before the COVID-19 pandemic, with a waste composition of 61.40% being food scraps and food packaging and 38.60% being plastic waste. This is due to changes in the lifestyle of most students. This increase in waste generation means that waste management in S Building needs to be readjusted to the composition of the waste produced, by applying the 3R concept.Keywords: waste management, college buildings, the â€˜new normalâ€™ era
PENINGKATAN KEMAMPUAN BERPIKIR KRITIS SISWA KELAS IV MELALUI MODEL PEMBELAJARAN PROBLEM BASED LEARNING (PBL)
Authors: Syawaluddin Ahmad , Basri Syamsurijal , Sari Nur Indah
Published: March 2024

Penelitian ini, Penelitian Tindakan Kelas yang bertujuan untuk mendeskripsikan penerapan model pembelajaran Problem Based Learning dalam meningkatkan kemampuan berpikir kritis siswa kelas IV SD Negeri Unggulan Bontomanai pada mata pelajaran Ilmu Pengetahuan Alam dan Sosial (IPAS). Teknik pengumpulan data yang digunakan yaitu observasi dan tes evaluasi. Hasil observasi siklus I pada aktivitas mengajar guru berada pada kategori cukup (C), aktivitas belajar siswa pada kategori kurang (K) dan tes kemampuan berpikir kritis siswa pada kategori belum tuntas. Pada siklus II hasil observasi aktivitas mengajar guru pada kategori baik (B), aktivitas belajar siswa pada kategori baik (B) dan tes kemampuan berpikir kritis siswa pada kategori tuntas. Kesimpulan penelitian menunjukkan bahwa penerapan model Problem Based Learning dapat meningkatkan kemampuan berpikir kritis siswa pada mata pelajaran Ilmu Pengetahuan Alam dan sosial (IPAS) siswa kelas IV SD Negeri Unggulan Bontomanai Kabupaten Gowa.
Penerapan Model Kooperatif Make A Match Untuk Meningkatkan Hasil Belajar Materi Udara Bersih Bagi Kesehatan
Authors: Reskiani Widia , Amran Muhammad , Nurmawati Nurmawati
Published: March 2024

Penelitian ini dilatar belakangi oleh hasil belajar siswa kelas V SDN 231 LIU, Kabupaten Wajo yang belum mencapai SKBM. Tujuan penelitian ini adalah meningkatkan proses dan hasil belajar tentang udara bersih bagi kesehatan siswa melalui penerapan model pembelajaran kooperatif tipe make a match di kelas V SDN 231 LIU. Penelitian ini merupakan penelitian tindakan kelas (PTK) dan menggunakan pendekatan kualitatif. Subjek dalam penelitian ini adalah guru dan siswa kelas V SDN 231 LIU yang berjumlah 20 siswa terdiri dari 8 siswa perempuan dan 12 siswa laki-laki. Penelitian ini terdiri dari siklus I dan siklus II. Teknik pengumpulan data yang digunakan yakni observasi, tes, dan dokumentasi. Pada siklus I hasil observasi guru yaitu 80% (B), untuk hasil observasi siswa yaitu 74,6% (C) dan hasil tes belajar siswa yaitu 74,9 (C). Pada siklus II hasil observasi guru yaitu 86,6% (B), untuk hasil observasi siswa yaitu 89,1% (B) dan hasil tes belajar siswa yaitu 84,5% (B). Kesimpulannya yaitu penelitian ini menunjukkan bahwa dengan penerapan model pembelajaran pembelajaran kooperatif tipe make a match dapat meningkatkan proses dan hasil belajar tentang udara bersih bagi kesehatan siswa kelas V SDN 231 LIU, Kabupaten Wajo.
Pengembangan Media Pembelajaran Berbasis Augmented Reality Berkonteks Etnomatematika Pada Candi Borobudur
Authors: Widodo Ridwan , Indiati Intan , Shodiqin Ali , Nursyahidah Farida
Published: March 2024

Media pembelajaran merupakan alat yang digunakan untuk membantu dalam proses belajar mengajar. Kurangnya implementasi media pembelajaran yang menarik membuat siswa bosan dengan suasana belajar. Mengakibatkan kurangnya partisipasi aktif siswa dalam pembelajaran. Augmented reality adalah salah satu bentuk media yang bisa digunakan sebagai media pembelajaran di era sekarang. Bentuk dari AR sendiri mengimplementasikan dunia maya ke dalam dunia nyata. Pembelajaran matematika akan lebih menyenangkan apabila bisa dikaitkan dengan kehidupan sehari-hari. Tujuan dari penelitian ini adalah untuk mengembangkan media pembelajaran berbasis AR yang berkonteks etnomatematika pada candi borobudur. Adanya keterkaitan konteks candi borobudur dengan AR akan membantu siswa dalam proses pembelajaran matematika pada materi barisan dan deret. Metode yang digunakan dalam penelitian ini adalah ADDIE. Hasil penelitian yang diperoleh adalah bahwa media yang dihasilkan mendapat kelayakan sebesar 88% berdasarkan angket respon siswa, validasi kelayakan media 87% dan kelayakan materi 94% dari validator ahli, terjadi rata-rata hasil belajar media AR yang lebih baik dibanding pembelajaran secara konvensional, terjadi keaktifan belajar siswa sangat baik pada saat menggunakan media AR.
APLIKASI VIRTUAL REALITY SEBAGAI MEDIA INFORMASI KAMPUS UTAMA UNIVERSITAS PGRI SEMARANG BERBASIS ANDROID
Authors: Abdul Rochman Nur Hidayat , Nuroso Harto , Wibisono Arif
Published: March 2024

Virtual Reality atau realitas maya adalah sebuah teknologi yang telah membuat perbedaan besar pada sejarah pemikiran manusia dan saat ini sedang menjadi trend. Dimana teknologi virtual dapat mensimulasikan keadaan di dunia nyata kedalam dunia maya, dengan kata lain seseorang dapat merasakan kondisi yang nyata tetapi dalam dunia maya. Sedangkan penyampaian informasi kampus bangunan kampus oleh Universitas PGRI Semarang masih melalui media cetak seperti pada umumnya dalam bentuk 2D, gambar 2D, dan brosur yang dihasilkan sangat terlihat monoton, kurang detail mengenai informasi bengunan kampus gambar ruangan. Dengan aplikasi ini user dapat mengetahui informasi lebih banyak terutama pada ruang perkuliahan dan ruang lainnya yang menunjang pembelajaran. Aplikasi Virtual Reality sebagai Media Informasi Kampus Utama Universitas PGRI Semarang ini berbasis android. Metode penelitian yang digunakan dalam mengembangkan aplikasin ini  adalah metode waterfall Model sampai ke pengujian system. Menghasilkan Aplikasi Virtual Reality sebagai Media Informasi Kampus Utama Universitas PGRI Semarang, menampilkan objek bangunan secara 3D. Pada proses pengujian yang dilakukan oleh 2 ahli memperoleh presentase rata rata 90%, kesimpulannya bahwa aplikasi ini layak digunakan, sedangkan untuk hasil pengujian pengguna ( uji usability ) memperoleh presentase rata-rata 8.5% yang artinya bahwa pengguna Sangat puas dalam penggunaanya dan layak digunakan.
PERANCANGAN SISTEM INFORMASI PADA PENJUALAN HIJAB TOKO KHANZANAH WIN BERKAH
Authors: Indrarti Wahyu , Rani Rani , Widiastuti Reni , Roni Faisal
Published: March 2024

Abstract :In this era globalization, information technology is one of the fields whose development is accelerating. Information technology gives a lot of influence in the  life of the people and computers become the most sophisticated alternative in handling the right and accurate information . Khanzanah Win Berkah is a trading business engaged in fashion that the system is still manual and has not been computerized starting from recording data items, the sales transaction process to making report so as to make the store's performance less effective and efficient . Therefore, there needs to be a system that can facilitate employees in doing their jobs. For this reason, the author tries to make a Final Project on the design of sales information systems at KhanzanahWin Berkah. And the model used to design this software uses the waterfall model. The design of this information system is the best solution to solve existing problems in the shop and with a computerized system that can improve shop performance more effectively and efficiently so the data stored is save and reduces errors in data calculation.
KELAYAKAN SISTEM INFORMASI PELAYANAN KESEHATAN PUSKESMAS DUKUH SETI
Authors: Menarianti Ika , Nada Ashifa Khoiron , Sudargo Sudargo
Published: March 2024

Puskesmas merupakan pusat pelayanan kesehatan yang banyak digunakan oleh masyarakat. Untuk melaksanakan pelayanan operasional dibutuhkan sebuah sistem informasi pelayanan kesehatan yang mudah digunakan dan membantu meningkatkan proses pelayanan agar lebih baik. Upaya yang dilakukan adalah dengan membangun Sistem Informasi Pelayanan Kesehatan Pusekesma Dukuhseti. Pengujian sistem yang digunakan  adalah dengan menguji sistem menggunakan Blak Box Testing  yang tujuannya untuk menentukan fungsionalitas dari sistem yang dibangun apakah berjalan dengan baik dan valid.  Sedangkan untuk mengetahui kelayakan sistem digunakan hasil pengujian yang dilakukan oleh ahli materi dan ahli media serta responden. Berdasarkan hasi pengujian diperoleh bahwa semua tombol dan menu dapat berfungsi dengan baik dan valid.  Untuk Kelayakan Sistem Informasi Pelayanan Kesehatan Pusekesma Dukuhseti  dilakukan oleh dua validasi ahli materi dari Puskesmas Dukuhseti diperoleh nilai sebesar 81,35% dan dinyatakan sangat Layak, dua valisasi ahli media dari Dinas KOMINFO Semarang diperoleh nilai sebesar 84,65% dan dinyatakan sangat Layak serta beberapa   hasil sebesar 87,5% dan dinyatakan Sangat Layak digunakan
E-Schedule Agenda Kegiatan Pegawai Dinas Pengendalian Penduduk Dan Keluarga Berencana Kota Semarang Berbasis Web
Authors: Sri Wahyuningsih Eka , Khoiri Nur , Wijayanto Wijayanto
Published: March 2024

ABSTRAK Dinas  Pengendalian  Penduduk  dan  Keluarga  Berencana  Kota  Semarang  memilili berbagai bidang yaitu bidang pengendalian penduduk, bidang keluarga berencana, bidang penyuluhan dan penggerakan, bidang ketahanan kesejahteraan keluarga. Setiap bidang memiliki tugas  dan  kegiatan  yang berbeda-beda.  Dalam  penyusunan  agenda kegiatan  disetiap  bidang biasanya masih menggunakan cara manual, yaitu dengan cara diketik biasa melalui laptop/komputer kemudian dicetak. Jadwal kegiatan tersebut lalu disimpan oleh bagian arsip data disetiap bidang. Karena penyimpanan dan penginputan jadwal kegiatan masih manual sehingga sering terjadi hilangnya arsip jadwal kegiatan tersebut. Oleh karena itu perlu diatasi dengan membuat website khusus jadwal agenda kegiatan kantor. Tujuan dari penelitian ini adalah membuat website e-schedule agenda kegiatan untuk media penyimpanan jadwal kegiatan supaya lebih terstruktur.   Model pengembangan yang digunakan untuk website ini adalah model pengembangan waterfall. Model Waterfall dapat digunakan untuk bentuk pengembangan website yaitu (1) analysis, (2) desaign, (3) coding, (4) testing dan (5) Maintenance. Desain system dalam pembuatan meliputi pembuatan flowchart, use case diagram, activity diagram, dan sequence diagram. Kemudian diimplementasikan dalam bahasa pemograman PHP, Code Igniter, HTML, CSS dengan menggunkan data base MySQL. Hasil penelitian menunjukkan bahwa penilaian validasi ahli dengan menggunakan skala Likert didapatkan hasil rata – rata oleh  tiga validator ahli materi sebesar   99%, 100% dan 75%, sehingga rata – rata dari ke tiga validator dapat dinyatakan layak digunakan. Kemudian penilaian dari responden menggunakan skala Guttman, memperoleh hasil rata – rata sebesar 99% dan dinyatakan layak digunakan.Kata Kunci : website, jadwal, Waterfall,  PHP, Code Igniter, HTML, CSS,MySql
PEMANFAATAN E-LEARNING MADRASAH SEBAGAI MEDIA PEMBELAJARAN PADA MASA PANDEMI COVID- 19 DI MTsN 5 KLATEN
Authors: Hayati Mardiyah
Published: March 2024

Tujuan  dari penelitian ini adalah untuk mengetahui penggunaan  E-Learning Madrasah yang merupakan  salah satu media pembelajaran daring di masa pandemic seperti saat ini . Penelitian ini adalah  penelitian kualitatif deskriptif dalam bentuk studi kasus. MTsN 5 Klaten adalah salah satu sekolah atau madrasah yang menggunakan aplikasi pembelajaran E-Learning Madrasah dalam kegiatan belajar mengajar di masa pandemi saat ini. Banyak kelebihan dan  juga kelemahan dalam proses pembelajaran menggunakan aplikasi E-Learning Madrasah. Kelebihan dari E Learning Madrasah fitur-fitur yang terdapat di dalamnya sebenarnya sudah komplit tetapi bagi anak yang kurang menguasai aplikasi ini akan timbul beberapa kendala yang dapat menghambat proses pembelajaran. Selain itu kendala jaringan dan akses internet didaerah tempat tinggal siswa membuat kegiatan  pembelajaran tidak berlangsung  secara optimal. Kata kunci : Media Pembelajaran,E-Learning madrasah. Pandemi Covid-19
APLIKASI PENGENALAN PERANGKAT INPUT DAN OUTPUT KOMPUTER BERBASIS AUGMENTED REALITY
Authors: Yuliana Lola , Supandi Supandi , Wijonarko Wijonarko
Published: March 2024

Dalam penyampaian materi pengenalan perangkat input dan output komputer pada mata pelajaran TIK di MTs.Al Islam Sumurrejo, Kecamatan Gunungpati, Kota Semarang, masih menggunakan cara konvensional yaitu berupa buku, teks tertulis dan mendengarkan penjelasan materi dari guru. Hal ini disebabkan kurangnya penguasaan guru terhadap model-model pembelajaran yang ada. Sehingga akan timbul kejenuhan dan kebosanan, karena tanpa adanya media belajar lain yang mendukung. Maka dari itu dibutuhkan media pembelajaran yang menarik untuk meningkatkan minat belajar siswa. Dengan adanya permasalahan tersebut, maka peneliti berinovasi membuat sebuah aplikasi pengenalan perangkat input dan output komputer berbasis augmented reality sebagai media untuk memudahkan dan meningkatkan minat siswa dalam belajar. Augmented Reality merupakan teknologi yang menggabungkan benda maya 2 dimensi dan 3 dimensi kedalam lingkungan nyata 3 dimensi.Penelitian ini menggunakan metode pengembangan peneliti dan pengembangan (Research & Development) sedangkan model pengembangannya menggunakan waterfall model. Target dalam penelitian ini adalah siswa Mts.Al Islam Sumurrejo, Kecamatan Gunungpati, Kota Semarang. Untuk pengujian kelayakan aplikasi menggunakan lembar angket uji validasi ahli materi dan validasi ahli media, serta lembar responden. Berdasarkan hasil validasi ahli media dan validasi ahli materi dimana ahli media mendapatkan nilai kelayakan 91,66% dan termasuk dalam kriteria “Sangat Layak” untuk digunakan. Sedangkan hasil nilai ahli materi mendapatkan nilai kelayakan 84,44% dan termasuk dalam kriteria “Sangat Layak” untuk digunakan, maka aplikasi pengenalan perangkat input dan ouput komputer dinyatakan valid. Selanjutnya dilakukan uji coba pengguna dengan instrumen menggunakan skala likert sebanyak 30 responden. Hasil dari aplikasi pengenalan perangkat input dan output komputer memperoleh hasil sebesar 80,92% dan termasuk dalam kriteria “Layak” untuk digunakan.
PENGEMBANGAN MEDIA PEMBELAJARAN SEJARAH INDONESIA BERBASIS ANDROID DENGAN PENDEKATAN KONTEKSTUAL DI SMK
Authors: Anwar Maulana Ahmad Nurul , Wibisono Arif , Buchori Achmad
Published: March 2024

Media pembelajaran merupakan terobosan baru pada dunia teknologi yang mampu menjadikan pembelajaran dikelas semakin lebih efektif, kreatif, dan menyenangkan serta dapat membuat peningkatan pada motivasi belajar siswa. penelitian ini bertujuan untuk menghasilkan Aplikasi berbasis android pada materi sejarah Indonesia untuk siswa SMK kelas 10 TKJ. Selain itu, penelitian ini juga dilakukan untuk mengetahui kelayakan Aplikasi yang dihasilkan berdasarkan aspek kevalidan, keefektifan, dan kepraktisan. Jenis penelitian ini merupakan peneltian dan pengembangan model ADDIE yang memiliki 5 tahapan yaitu: analisis (analysis), desain produk (design), pengembangan produk, (development), uji coba produk (implementation) dan evaluasi (evaluation). Instrument yang digunakan berupa lembar uji validitas, angket uji kepraktisan dan posttest. Lembar uji kevalidan bertujuan untuk mengetahui tingkat kevalidan, uji kepraktisan bertujuan untuk mengetahui tingkat kepraktisan dan posttest bertujuan untuk mengetahui tingkat keefektifan. Hasil penelitian menunjukan kualitas produk yang dihasilkan berdasarkan (1) aspek kevalidan memenuhi kriteria valid dengan rata-rata persentase validator sebesar91,66%, (2) aspek keefektifan memenuhi kriteria dengan ketuntasan belajar klasikal siswa sebesar 72,50%, (3) aspek kepraktisan memenuhi kriteria praktis dengan rata-rata total angket respon siwa sebesar 87%
SISTEM INFORMASI ADMINISTRASI NASABAH DI KSPPS NUR INSANI SEMARANG
Authors: Asmara Yudha , Khoiri Nur , Wijayanto Wijayanto
Published: March 2024

ABSTRACT- KSPPS Nur Insani is a sharia cooperative that has been established since 2013, almost 10 years running but still uses the old way of doing administration, namely with paper collections and installment books. This cooperative does not yet have an information system, it only has manual data archives. This process triggers fraud or inaccuracy of data in the collection process from both cooperatives and customers. This is also a supporting factor because in the current era many Indonesians like to use cellphones or laptops to keep records compared to using books or paper, because the system can minimize data loss when compared to paper or books. From some of these problems, a solution was provided, namely by creating a Customer Administration Information System at KSPPS Nur Insani Semarang which has 5 stages, namely: Communication, Planning, Modeling, Construction, and Deployment. In making the system using system design which includes: Flowcharts, Context Diagrams, DFD, ERD, Table Relations, DIPO. and use software including: PHP, MySQL, XAMPP, PHP, HTML, and Bootstrap. The results showed that the respondents' validation assessment using the Guttman scale as many as 15 respondents obtained an average result of 94% which was included in the "Very Eligible" criteria used. Then the results of the expert validation assessment using the Likert scale obtained an average result of 88.3% which was included in the "Very Eligible" criteria was used. Keyword : Information System, Administration, Customer
KEEFEKTIFAN PERMAINAN ENGKLEK UNTUK MENINGKATKAN FISIK MOTORIK ANAK KELOMPOK B DI TK MEKAR SARI KANDEMAN BATANG
Authors: Pujiono Pujiono , Purnamasari Iin , Muhtarom Muhtarom
Published: March 2024

Permainan engklek sebenarnya mempunyai karakteristik yang berdampak positif pada perkembangan anak. Permainan engklek dikenal sebagai permainan rakyat yang sangat dekat dengan dunia anak-anak. Permainan engklek dapat melatih gerakan motorik kasar bisa dilakukan, misalnya melatih anak berdiri di atas satu kaki. Penelitian ini dilaksanakan di TK Mekar Sari Kandeman Kabupaten Batang. Tujuan dari penelitian ini bertujuan untuk mengetahui keefektifan permainan engklek untuk meningkatkan fisik motorik anak kelompok B di TK Mekar Sari Kandeman Batang dan mengetahui respon anak-anak kelompok B di TK Mekar Sari terhadap permainan engklek. Desain yang digunakan dalam penelitian ini adalah desain Pretest-Posttest Control Group Design. Populasi dalam penelitian ini adalah peserta didik kelompok B TK Mekar Sari Kandeman Kab. Batang. Sampel dari penelitian berjumlah 32 responden. Permainan engklek dilakukan 14 kali dalam 1 bulan, penilaian perkembangan fisik motorik sebelum dan sesudah menggunakan Uji t-test pada taraf signifikansi 95% (α = 0,05). Hasil studi apakah motorik memiliki perbedaan setelah dan sebelum permainan tradisional, dengan nilai p 0,000 <α-0,05. Kesimpulan: Ada pengaruh permainan engklek terhadap perkembangan fisik motorik anak. Saran: Bagi guru; agar dapat menggunakan permainan tardisional engklek dalam proses belajar mengajar yang dapat meningkatkan perkembangan fisik motorik anak.