bluuebunny/crossref_metadata_2025 huggingface dataset:
Pembuatan Komposit Bentonit Dengan TiO2 Untuk Menurunkan Kadar COD Dan BOD Limbah Cair Ayam Potong
Authors: Sandi Dwi Kurnia , Baharianto Muhammad Yusuf , Chempro Sani , Astuti Dwi Hery
Published: August 2024

Pada era saat ini pembuatan komposit terus mengalami perkembangan oleh karena itu penelitian ini dilakukan dengan menggunakan bentonit dan TiO2 sebagai bahan baku pembuatan komposit bentonit-TiO2 sehingga dapat mening-katkan daya adsorpsi bentonit. Tujuan dari penelitian ini untuk mendapatkan komposit dengan rasio bentonit danTiO2 yang tepat mampu meningkatkan daya adsorpsi, sehingga dapat menurunkan kandungan COD dan BOD limbah cair penyembelihan ayam potong.pembuatan komposit bentonit-TiO2 ini dilakukan dengan cara mencampurkan kedua ba-han yang telah dilakukan perlakuan awal yaitu bentonit dan TiO2 lalu diaduk dengan kecepatan 1500 rpm. Kemudian perlakuan yang diberikan yaitu perbandingan massa bentonit dan TiO2 dengan variasi 1:1 , 2:1 3:1 , 4:1 , 5:1 dan waktu pengadukan 15, 20, 25, 30, 35 menit. Kemudian komposit yang telah dibuat akan digunakan untuk adsorpsi COD dan BOD limbah cair ayam potong. Sehingga dari penelitian diperoleh hasil komposit terbaik pada variasi bentonit dan TiO2 2:1 dan pengadukan selama 30 menit, dengan %penurunan COD sebesar 47.87% dan %penurunan BOD sebesar 55.81%. Hasil analisa SEM pada perbesaran 2000 kali dapat terlihat bentuk morfologi komposit bentonit-TiO2 yang beragam dengan diameter partikel sebesar 20.0 μm.
Pemanfaatan Air Leri sebagai Bahan Baku Pembuatan Pupuk Struvite
Authors: Permatasari Dewi , Rosadi Rosalina , Chempro Sutiyono , Edahwati Luluk
Published: August 2024

Air cucian beras hasil buangan dari rumah tangga yang mengandung kadar magnesium cukup tinggi dapat diolah menggunakan teknologi kristalisasi struvite. Struvite adalah kristal putih yang terdiri dari magnesium, amonium dan fosfor dalam konsentrasi yang sama (MgNH4.PO4.6H2O). Penelitian ini dilakukan dalam skala laboratorium dengan berbagai variabel yaitu pH larutan dan kecepatan udara yang berlangsung di reactor kolom bersekat miring. pH yang akan digunakan adalah 8,9,10 dan 11. Sedangkan kecepatan pengadukan yang digunakan adalah 1; 1,5; 2; 2,5 L/min. Dari penelitian ini didapatkan kondisi terbaik yaitu Ph 10 dan rate udara 2 liter/menit, struvite yang dihasilkan memiliki kandungan magnesium 3,7% dan pospat 31,5 %.
ANALISIS KUALITAS LAYANAN RATRI TOBAT TERHADAP KEPUASAN PASIEN RAWAT JALAN DI RSUD BENDAN KOTA PEKALONGAN
Authors: Priagung Andri , Fatkhiya Musa Firi
Published: August 2024

Di instalasi farmasi poli rawat jalan RSUD Bendan memiliki sistem antrian pengambilan obat yang baru diluncurkan pada 17 Juli 2023 yaitu layanan RATRI TOBAT. Penelitian ini bertujuan untuk menganalisa kualitas layanan RATRI TOBAT terhadap kepuasan pasien rawat jalan di RSUD Bendan. Penilaian kualitas layanan RATRI TOBAT dilihat dari indikator mutu pelayanan kesehatan sedangkan kepuasan pasien dilihat dari indikator dimensi kepuasan.
UJI AKTIVITAS ANTI INFLAMASI TERHADAP MENCIT PUTIH JANTAN (Mus musculus) EKSTRAK METANOL KULIT BAWANG MERAH (Allium cepa L.)
Authors: Cantika Maria Tri , Tutik Tutik , Nofita Nofita
Published: August 2024

ABSTRAKKulit bawang merah (Allium cepa L.) mengandung banyak senyawa kimia, seperti flavonoid. Flavonoid yang terkandung dalam kulit bawang merah adalah kuersetin. Kuersetin adalah golongan senyawa yang memiliki aktivitas anti inflamasi. Penelitian ini bertujuan untuk mengetahui apakah ekstrak metanol kulit bawang merah memiliki aktivitas anti inflamasi terhadap mencit putih jantan (Mus musculus).Penelitian ini dilakukan ekstraksi menggunakan metode refluks dengan pelarut metanol. Ekstrak yang di peroleh diukur kadarnya menggunakan spektrofotometri UV-Vis. Penelitian dilakukan dengan memberikan karagenin sebagai mediator radang pada telapak kaki mencit, lalu pemberian secara oral suspensi ekstrak metanol kulit bawang merah dengan dosis I (175mg/kgBB), dosis II (200mg/kgBB), dan dosis III (250 mg/kgBB), Na-CMC (kontrol negatif) dan Kalium diklofenak (kontrol positif). Hasil % rendemen ekstraksi kulit bawang merah dengan metode refluks diperoleh sebesar 15,7%. Hasil penetapan kadar flavonoid yang diperoleh sebesar 21,57%. Hasil uji aktivitas antiinflamasi ekstrak metanol kulit bawang merah diperoleh dosis 175 mg/kgBB sudah memberikan aktivitas antiinflamasi. Hasil uji Post Hoc LSD dengan nilai < 0,05 yang berarti ekstrak metanol kulit bawang merah mampu memberikan aktivitas anti inflamasi terhadap mencit dengan dosis optimal 250 mg/kgBB.
EFEK ASAM ALFA-LIPOAT TERHADAP AKTIVITAS ANTIOKSIDAN NLC EKSTRAK TEH HIJAU DENGAN METODE DPPH
Authors: Afra Fairuz Yaumil , Soeratri Widji , Purwanto Djoko Agus
Published: August 2024

Ekstrak teh hijau senyawa yang berperan sebagai antiaging namun memiliki kelarutan yang sangat rendah dalam lipid sehingga dibuat sistem pembawa Nanoparticle Lipid Carrier (NLC). NLC ekstrak teh hijau mengalami fotodegradasi sehingga dilakukan penambahan ko-antioksidan yaitu asam alfa-lipoat. Penelitian ini bertujuan untuk membandingkan efek asam alfa-lipoat terhadap aktivitas antioksidan. Penelitian menggunakan metode eksperimental dengan F1 (tanpa asam alfa-lipoat) , F2 (1%) dan F3 (1,5%). Penelitian dilakukan dengan mengukur nilai penghambatan menggunakan metode DPPH dengan melakukan penyinaran UV sebelum dan sesudah 21 jam. Dari uji analisis statistik didapatkan hasil tidak ada perbedaan bermakna sebelum dan sesudah penyinaran UV selama 21 jam. Nilai persen penghambatan DPPH pada F2 dan F3 lebih tinggi dibandingkan F1. Penambahan asam alfa-lipoat memberikan aktivitas antioksidan lebih tinggi dibandingkan tidak menggunakan asam alfa-lipoat
FORMULASI DAN UJI EVALUASI FISIK SEDIAAN LOSIO MINYAK ATSIRI BATANG SERAI WANGI (Cymbopogon nardus L.) SEBAGAI REPELAN TERHADAP NYAMUK Aedes aegypti
Authors: Maulana Difa Aryan , Hidayaturahmah Rizky , Ulfa Ade Maria
Published: August 2024

Penyakit Demam Berdarah Dengue (DBD) adalah salah satu penyakit yang di sebabkan oleh virus dengue yang dapat kapan saja bisa menular melalui gigitan nyamuk Aedes aegypti ke manusia yang masih menjadi masalah kesehatan masyarakat di Indonesia. Dibutuhkan produk repellan yang aman yang berasal dari tanaman yang aman salah satunya yaitu batang serai wangi. Tujuan penelitian ini untuk mengetahui evaluasi fisik sediaan losio dan untuk mengetahui berapakah konsentrasi ekstrak batang serai wangi (Cymbopogon nardus L.) dalam sediaan losio yang memiliki efektivitas sebagai daya tolak terhadap nyamuk Aedes aegypti. Ekstraksi menggunakan metode destiasi uap air dengan pelarut aquades. Hasil rendemen yang didapat dari metode destilasi yaitu 0,035. Sediaan losio ekstrak daun serai wangi (Cymbopogen nardus L.) dengan konsentrasi 0,5% memenuhi persyaratan uji evaluasi fisik yang baik meliputi uji organoleptik, homogenitas, uji pH, uji daya sebar, uji daya lekat, uji iritasi, dan uji hedonik. Hasil penelitian menunjukkan bahwa sediaan losio formula III dengan konsentrasi 1,5% merupakan sediaan yang paling baik karena memiliki efektivitas terhadap nyamuk aedes aegypti pada 30 detik dan tidak efektif pada jam ke 6 dengan syarat diatas 80% kemudian data diuji menggunakan repeated measures ANOVA yang diperoleh nilai signifikan yaitu <0,05.
NURSING CARE ANALYSIS OF ARTIFICIAL RESPIRATORY MANAGEMENT IN STROKE-ASSOCIATED PNEUMONIA (SAP) PATIENTS: A CASE STUDY FROM ICU RSPAL DR. RAMELAN SURABAYA
Authors: Ababiel Dinda Rimyatul
Published: August 2024

Introduction: Stroke-associated pneumonia (SAP) is a common complication of stroke, leading to ineffective airway clearance and potentially severe outcomes such as respiratory failure and death.
Objective: This case study analyzes the nursing care provided to a SAP patient in the ICU of RSPAL Dr. Ramelan Surabaya, focusing on the application of artificial respiratory management to improve airway clearance
Methods: Over five days, the nursing team implemented interventions, including Endotracheal Tube (ETT) care, which partially resolved the ineffective airway clearance.
Results: This improvement was evident in the enhanced respiratory parameters and reduced secretion accumulation.
Conclusions: The findings highlight the importance of diligent airway management in preventing respiratory complications in SAP patients.
Preferencias y comportamiento del mercado colombiano frente al maquillaje cosmético orgánico y natural
Authors: Barajas Osorio Lina Vanessa , Montenegro García Laura Valentina , Palacio García Natalia Andrea
Published: August 2024

El artículo de investigación se centró en identificar el comportamiento de las consumidoras de maquillaje y sus conocimientos frente al maquillaje natural y orgánico; las revisiones bibliográficas que respaldan la investigación estudian el comportamiento poblacional, características, evolución de la industria cosmética y las oportunidades de Colombia. Por ende, el estudio es relevante para la industria colombiana, ya que se identificaron las preferencias de compra de consumidoras entre 20 y 26 años de edad de la Fundación Universitaria del Área Andina ubicada en la ciudad de Bogotá, por medio de entre vistas que hacen parte del método cualitativo fenomenológico, el cual fue empleado para analizar de forma subjetiva los resultados suministrados, los cuales indican una coincidencia en su comportamiento; se evidencia que el precio y la calidad inciden en las decisiones de consumo y que no hay un amplio conocimiento sobre la industria de maquillaje orgánico y natural, ni de su proveniencia
La implicación laboral de la apropiación del rol del educador físico como readaptador físico deportivo. Revisión sistemática
Authors: Díaz Velásquez Valeria , Afanador Restrepo Diego Fernando
Published: August 2024

La situación profesional del docente de Educación Física en su aplicación dentro del área de rehabilitación física es muy reducida. Por eso, esta investigación pretende exponer la implicación laboral de la apropiación del rol del educador físico como readaptador físico deportivo, por medio de una revisión sistemática de 12 artículos publicados. Así mismo, obtener un diagnóstico respecto a la utilidad rehabilitadora y el grado de influencia de los licenciados con relación a su continua evolución dentro del campo de las ciencias humanas, sociales y de la salud. Respecto a los resultados del objeto de estudio, se evidenció que aún es bastante incipiente la actuación del educador físico en el nicho de la readaptación física deportiva
A tanulás gamifikációja
Authors: Atiyat Diala , Alsoub Abeer , Rawashdeh Taiseer , Tabbalat Shereen , Al-Hiary Hanaa
Published: August 2024

Az építészeti oktatás fejlesztése gamifikációval a tervezési alapképzésen. Az építészeti kompozíció tárgy egyetemünkön az építészeti oktatás alapképzésének része, ahol a hallgatók megtanulják a különböző elemek tervekben való koherens szintetizálását. A sakk mint gamifikációs eszköz integrálása az építészeti oktatásba a sakkban rejlő stratégiai gondolkodás és a kreatív tervezési folyamatok közötti szinergián alapul. Ez az integráció kihasználja a sakk problémamegoldó dinamikáját az innovatív tervezési megoldások ösztönzésére, igazodva a tanulás kognitív elméleteihez. A gamifikációs elvek, például a motiváció és az elköteleződés beépítésével a megközelítés hozzájárul a diákok kreativitásához, elkötelezettségéhez, készségeik holisztikus fejlesztéséhez. A tanulmány célja, hogy felmérje a sakk gamifikációs integrálásának hatását az építészeti tervezési kreativitásra és a hallgatók elkötelezettségére. Feltárja ennek az innovatív megközelítésnek az elméleti alapjait, módszertanát, eredményeit és következményeit.
Táncol, játszik, épít...
Authors: Fazekas Katalin
Published: August 2024

KISBALÁZS BÖLCSŐDE, GÖDÖLLŐ A Vikár és Lukács építésziroda által tervezett Kisbalázs Bölcsőde egy központi, úgynevezett „Bóbita", más néven „Ringató-tér" köré szervezett hat csoportszobás intézmény. Az egyedi funkcióval rendelkező bölcsődeépületben a zenének, az irodalomnak, a vizuális művészeteknek kiemelt szerepet szántak az alkotók. A helyszín Gödöllő fiatalos korösszetételű Fenyves, Egyetem és Alvég városrészeinek határa, egyik oldalon vonatsínek és forgalmas utca, másik oldalon kisvárosias beépítés.
Debut de Miastenia Gravis G700.
Authors: Ramón N. Tailin Kareli , Granadillo S. Grisel , Serrano P. Andrea
Published: August 2024

Objetivo: Aplicar el proceso de enfermería a paciente con diagnóstico de miastenia gravis. Caso clínico: Se trata de una paciente femenina de 38 años de edad, sin antecedentes patológicos conocidos, quien inicia su enfermedad actual 2 días previos a su ingreso a la Unidad de Cuidados Intensivos (UCI), caracterizado por hipotensión, anuria, hipoperfusión distal y taquipnea. En vista del deterioro progresivo del estado de conciencia, es ingresada a la unidad con diagnóstico médico de síndrome miasteniforme a descartar; egresa a su domicilio 14 días posteriores al inicio de la enfermedad. Métodos: Estudio de caso con enfoque cualitativo; en la valoración se utilizó la teoría de las 14 necesidades de Virginia Henderson. Para los diagnósticos se utilizaron la taxonomía NANDA I-, los resultados esperados (NOC) y las intervenciones de enfermería (NIC), entre los que se encuentran deterioro del intercambio de gases, deterioro de la integridad tisular y dolor agudo. Resultados: La evolución de la paciente fue favorable y posterior al alta continúa con fisioterapia a domicilio. Conclusión: El diagnóstico deterioro de la integridad cutánea tuvo como puntuación de cambio con base en los indicadores temperatura de la piel +3 y perfusión tisular +2.
IDENTIFIKASI KUALITAS AIR SUMUR AKIBAT INTRUSI AIR LAUT DI LABUHA, KECAMATAN BACAN
Authors: Ahmayanti Baiki Vetty Dwi , K. Misbah Zulkarnain , Ahmad Badrun , Nagu Nani , Taufiq Yuda Saputra Muhammad
Published: August 2024

Intrusi air laut merupakan suatu fenomena yang umum terjadi pada pesisir pantai secara alami dan buatan yang disebabkan oleh air tanah yang sering diambil untuk kebutuhan masyarakat dan sebagainya tanpa adanya pengendalian yang baik. Tujuan penelitian ini untuk mengetahui kualitas air sumur akibat intrusi air laut di Labuha, Kecamatan Bacan. Berdasarkan parameter-parameter yang dianalisis yaitu Ph, TDS, Suhu, Salinitas, Konduktivitas, dan Specific Gravity. Jenis penelitian yang dipakai adalah jenis penelitian deskriptif yang dilakukan menggunakan metode kuantitatif. Terdapat 10 titik pengambilan sampel pada Lokasi penelitian dengan menggunakan Water Checker. Berdasarkan hasil dapat disimpulkan bahwa kualitas air sumur di labuha, kecamatan bacan bisa dikatakan kurang baik. Dilihat dari keenam parameter yang dipakai itu melewati standar yang diizinkan Peraturan Mentri Kesehatan Republik Indonesia Nomor 2 Tahun 2023 sehingga tidak layak untuk diminum. Akan tetapi masih bisa dipakai untuk keperluan air bersih seperti mencuci, mandi dan yang lainya. Kata kunci: intrusi air laut, air sumur, kualitas air
PENGARUH PENAMBAHAN SERBUK KAYU TERHADAP KUAT TEKAN BETON DENGAN BAHAN TAMBAH BESTMITTEL
Authors: Suprianto Suprianto , Hamka Hamka , Misbahuddin Misbahuddin
Published: August 2024

Beton adalah campuran antara semen Portland atau semen hidrolis lainnya, agregat halus, agregat kasar dan air, dengan atau tanpa bahan tambahan (admixture). Serbuk kayu merupakan salah satu serat alami (cellulose fibers) yang dapat digunakan sebagau zat tambah dalam campuran beton. Jikalau perlu menambahkan atau memanfaatkan limbah-limbah alam, Untuk mengetahui pengaruh serbuk kayu dan bestmittel terhadap kuat tekan beton maka dilakukan penelitian dengan menggunakan serbuk kayu yang bersumber dari hasil limbah pengrajin kayu. Metode penelitian ini menggunakan metode eksperimental yang dilakukan di laboratorium struktur dan bahan Universitas Muhammadiyah Parepare. Penelitian menunjukkan bahwa nilai kuat tekan beton normal kubus dan silinder adalah 25,76 dan 25,38 Mpa. Pada penambahan variasi 2,5% serbuk kayu dan 0,5% bestmittel didapat kuat tekan beton kubus dan silinder 28,21 dan 27,74 Mpa. Namun, pada variasi serbuk kayu 5% dan 0,5% bestmittel didapat kuat tekan beton kubus dan silinder 24,16 dan 23,97 Mpa. Sedangkan pada variasi 7,5% serbuk kayu dan 0,5% bestmittel didapatkan kuat tekan beton kubus dan silinder 21,80 dan 21,23 Mpa. Dari hasil penelitian ini didapat kesimpulan bahwa penggunaan serbuk kayu pada variasi 2,5% dan bestmittel 0,5% efektif dalam meningkatkan kuat tekan beton.
From RP to Global Adaptability: Examining Language Education Trends in Russian Universities
Authors: Samoshkina Irina , Klyukina Evgeniya
Published: August 2024

For decades, Russian higher education institutions have favoured British English, particularly Received Pronunciation (RP), as the academic standard. Adhering to these norms, they often overlook the importance of exposing students to a variety of accents, mistakenly viewing deviations from RP as academically inferior. This approach limits students' ability to master English comprehensively for global communication as the contemporary reality of English requires a more expansive and inclusive pedagogy. This study investigates the alignment between English instruction preferences of students and faculty members at the Russian Presidential Academy of National Economy and Public Administration (RANEPA) in Moscow. It explores the reasons behind teachers' adherence to British pronunciation, analyses students' emerging needs, and questions the effectiveness of an RP-centric approach in fostering global communication skills. The survey collected responses from students at various academic levels and faculty members through an anonymous questionnaire featuring multiple-choice and open-ended questions. Results reveal a significant divergence between students' preferences and teachers' instructional focus. Most students learn English to interact with both native and non-native speakers and are aware of major English varieties. While students’ preferred pronunciation models vary, faculty members predominantly favour British English, particularly RP, as the instructional standard. The study concludes that students display a pragmatic and open-minded approach, desiring exposure to various English accents. This contrasts with teachers' preference for British English, which may hinder effective communication and cultural understanding. The study recommends a more inclusive approach in language instruction, exposing students to diverse English accents to better prepare them for global communication.
PENGARUH KEMUDAHAN PENGGUNAAN, MANFAAT DAN KEPERCAYAAN TERHADAP MINAT MENGGUNAKAN E-PAYMENT QRIS PADA GENERASI Z
Authors: Octaviani Leonarda Sukacita , Pranatasari Fransisca Desiana , Maridjo H. Hery
Published: August 2024

The use of QRIS-based electronic money has become very popular as a non-cash payment system because society has shifted to non-cash payments. This study aims to determine the influence of ease of use, benefits, and trust on the interest in using QRIS e-payment. The research method used is descriptive quantitative. The population in this study includes all Generation Z individuals who have used QRIS e-payment in the past year and reside in the Special Region of Yogyakarta. The sampling technique employed is purposive sampling, with a sample of 96 Generation Z individuals who have used QRIS e-payment. The instrument testing technique includes validity and reliability tests. Data analysis uses multiple linear regression, and data processing is conducted with IBM SPSS Statistics 26. The results of this study indicate that ease of use does not affect the interest in using QRIS e-payment, benefits affect the interest in using QRIS e-payment, and trust affects the interest in using QRIS e-payment.
Optimization of percutaneous coronary intervention using new stent designs and individualized antiplatelet therapy
Authors:   , van Hemert Nicole Daniëlle
Published: August 2024

Great improvement in the percutaneous treatment of obstructive coronary artery disease have been made over the past few decades. Recent developments have focused on alterations in stent design and the duration of dual antiplatelet therapy. The ReCre8 trial assessed clinical outcomes after implantation of the permanent polymer zotarolimus-eluting stent versus the polymer-free amphilimus-eluting stent, in both stable coronary artery disease and acute coronary syndromes. A special focus on patients with diabetes mellitus demonstrated a potential enhanced efficacy of a drug-eluting stent with an amphilimus formula, which appeared to be most pronounced in the first year following percutaneous coronary intervention. A short dual antiplatelet therapy duration of one month was assessed in patients with troponin-negative disease, demonstrating low rates of stent thrombosis after three years.
Disease-Associated Variants in GRIN1, GRIN2A and GRIN2B genes: Insights into NMDA Receptor Structure, Function, and Pathophysiology
Authors: Korinek M , Candelas Serra M , Abdel Rahman F E S , Dobrovolski M , Kuchtiak V , Abramova V , Fili K , Tomovic E , Hrcka Krausova B , Krusek J , Cerny J , Vyklicky L , Balik A , Smejkalova T
Published: August 2024

N-methyl-D-aspartate receptors (NMDARs) are a subtype of ionotropic glutamate receptors critical for synaptic transmission and plasticity, and for the development of neural circuits. Rare or de-novo variants in GRIN genes encoding NMDAR subunits have been associated with neurodevelopmental disorders characterized by intellectual disability, developmental delay, autism, schizophrenia, or epilepsy. In recent years, some disease-associated variants in GRIN genes have been characterized using recombinant receptors expressed in non-neuronal cells, and a few variants have also been studied in neuronal preparations or animal models. Here we review the current literature on the functional evaluation of human disease-associated variants in GRIN1, GRIN2A and GRIN2B genes at all levels of analysis. Focusing on the impact of different patient variants at the level of receptor function, we discuss effects on receptor agonist and co agonist affinity, channel open probability, and receptor cell surface expression. We consider how such receptor-level functional information may be used to classify variants as gain-of-function or loss-of-function, and discuss the limitations of this classification at the synaptic, cellular, or system level. Together this work by many laboratories worldwide yields valuable insights into NMDAR structure and function, and represents significant progress in the effort to understand and treat GRIN disorders.
Influence of Lipid Class Used for Omega-3 Fatty Acid Supplementation on Liver Fat Accumulation in MASLD
Authors: Sabinari I , Horakova O , Cajka T , Kleinova V , Wieckowski MR , Rossmeisl M
Published: August 2024

Metabolic dysfunction-associated steatotic liver disease (MASLD) occurs in subjects with obesity and metabolic syndrome. MASLD may progress from simple steatosis (i.e., hepatic steatosis) to steatohepatitis, characterized by inflammatory changes and liver cell damage, substantially increasing mortality. Lifestyle measures associated with weight loss and/or appropriate diet help reduce liver fat accumulation, thereby potentially limiting progression to steatohepatitis. As for diet, both total energy and macronutrient composition significantly influence the liver’s fat content. For example, the type of dietary fatty acids can affect the metabolism of lipids and hence their tissue accumulation, with saturated fatty acids having a greater ability to promote fat storage in the liver than polyunsaturated ones. In particular, polyunsaturated fatty acids of n-3 series (omega-3), such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), have been intensively studied for their antisteatotic effects, both in preclinical animal models of obesity and hepatic steatosis and in overweight/obese patients. Their effects may depend not only on the dose and duration of administration of omega-3, or DHA/EPA ratio, but also on the lipid class used for their supplementation. This review summarizes the available evidence from recent comparative studies using omega-3 supplementation via different lipid classes. Albeit the evidence is mainly limited to preclinical studies, it suggests that phospholipids and possibly wax esters could provide greater efficacy against MASLD compared to traditional chemical forms of omega-3 supplementation (i.e., triacylglycerols, ethyl esters). This cannot be attributed solely to improved EPA and/or DHA bioavailability, but other mechanisms may be involved.
Faktor-faktor yang Berhubungan dengan Kecelakaan Kerja pada Operator Dump Truck di Bagian Produksi di Perusahaan Tambang Batubara
Authors: Nugroho Subagyo Amin , Akbar Sulung Alfianto , Rahmatullah Ilham
Published: August 2024

Sebuah perusahaan "Civil Work & Mining" di Indonesia mencatat 19 kasus kecelakaan kerja pada tahun 2022 dan 17 kasus pada tahun 2023 di bagian produksi. Pada tahun 2023, 13 insiden melibatkan operasi dump truck yang menyebabkan kerusakan properti, dimana 73% insiden disebabkan oleh perilaku tidak aman dan 27% oleh kondisi yang tidak aman. Meskipun angka kejadian kecelakaan kerja menurun, perusahaan tersebut belum mencapai zero incident. Tujuan penelitian ini untuk mengetahui faktor-faktor yang berkontribusi terhadap kecelakaan kerja pada operator dump truck. Penelitian ini menggunakan desain cross-sectional. Sebanyak 92 operator dump truck dipilih dengan purposive sampling dan disurvei melalui kuesioner online yang telah teruji validitasnya. Data diuji menggunakan uji chi-square dengan tingkat kepercayaan 95%. Hasil analisis menunjukkan hubungan yang signifikan antara kecelakaan kerja dengan perilaku tidak aman (p= 0,009), kelelahan kerja (p=0,029) dan penerapan standar operasional prosedur (SOP) (p=0,014). Rekomendasi meliputi pengembangan pelatihan dan pendidikan keselamatan berkelanjutan untuk meningkatkan kesadaran operator tentang risiko perilaku tidak aman, meningkatkan pengawasan dan kontrol terhadap aktivitas yang berisiko, menerapkan manajemen kelelahan, dan memperkuat kepatuhan terhadap SOP.
The Value of Education in Kaba Siti Kalasun by Syamsuddin ST. Radjo Endah
Authors: Finasti Anugrah Anggun , Nursaid Nursaid , Suhaili Samsudin , Ningsih Ayu Gustia , Noveria Ena
Published: August 2024

This research aims to describe the educational values ​​of the Siti Kalasun kaba using a sociological study of literature. The educational values ​​in question are the values ​​of faith and piety, aesthetic values, and the value of living together. The data source was obtained directly from Kaba Siti Kalasun herself. The type of research used is qualitative research with descriptive research methods. This research promotes understanding of the empirical interactions between the concepts being researched. This research reveals the educational values ​​in Kaba Siti Kalasun: as individuals, they demonstrate qualities such as love, patience, gentleness, and a life-oriented mindset; as members of society, they are characterized by their relationships with the environment and other people, along with a marked concern for the well-being of the environment and other people.
Moral, Educational and Social Values in The Novel Dia Adalah Kakakku by Tere Liye
Authors: Yessi Oktarina  , Ratu Wardarita  , Sri Wahyu Indrawati
Published: August 2024

The novel Dia Adalah Kakakku contains a story about the sacrifice of the main character, describing the person as a human being who prioritizes family, full of educational and social-moral values. This research aims to find out the values contained in the novel Dia Adalah Kakakku. The method used in this research is descriptive qualitative methods with data collection techniques using note-taking and documentation techniques, with data validity techniques using Triangulation. Research on this novel was carried out by analyzing the moral, educational, and social values in the novel Dia Adalah Kakakku. So the results obtained are that there are values contained in the novel, namely moral values, educational values, and social values.
Mophological Process of Acehnese Verbs in Album Rafly Kande
Authors: Istiqamah  , Putri Ananda Rizkyna  , Hijaratunnisa
Published: August 2024

Language is one of the most important elements that influences life and culture, as well as being the main means of human communication. Acehnese is one of the regional languages ​​that still lives in the Aceh region and is used by the majority of the population as a means of expressing their thoughts, feelings and desires. Morphology is the science that studies words and the influence of changes in word form on word groups and meanings. Songs can be interpreted as a variety of rhythmic sounds. This research aims to identify and analyze the morphological processes that occur in verbs in the Acehnese language contained in Rafli's albums. This aims to understand the morphological characteristics of verbs in the Acehnese language used in the context of music or works of art, especially in music albums produced by Rafli Kande. The method used is a qualitative descriptive method. The descriptive method is the presentation of data based on facts in accordance with those contained in Rafli's album. The data collection technique used was the technique of listening and noting the verbs in Rafli Kande's song lyrics. The results of this research show that there are four types of derivative verbs found in the Rafly Kande song album, namely the prefix meu- in the title of the song Aneuk Yatim, the prefix to the title of the song Gisa Bak Punca. The prefix neu- is in the title of the song Hoka Raja Loen, and the prefix geu- is found in the title of the song Rawa Tripa.
GRADE V STUDENTS’ CHARACTERISTICS OF MI AL-MULTAZAM IN THE ENGLISH LEARNING PROCESS AT ELEMENTARY ISLAMIC BOARDING SCHOOLS
Authors: Dariyanto  , Sahlan Fahmi
Published: August 2024

The aim of this research is to observe the characteristics of  grade V students at MI Al-Multazam in  English learning process. Students’ characteristics can be observed according to the students learning drive, learning style, and initial potential. Students (santri) are students at Islamic boarding school.  The children who are separated from their parents are in the process of development, both physically and psychologically. During their development, students have unique characteristics and are interesting to study in the learning process. Qualitative descriptive is the approach used by researchers in this research. Data was obtained through observation and interviews. The results of the research show that differences in student characteristics are a problem for educators in delivering foreign language learning material. Students tend to fluctuate in the English learning process. They have problems with unstable psychological conditions, learning styles that require teachers to use a variety of learning. Interest in learning English still requires intense motivation from teachers. The background of each student from various families and living independently in a boarding school greatly influences and adds to the uniqueness of how English is taught in Islamic boarding schools. Therefore, effective learning methods are needed, solutions by designing learning that is active, creative, effective and fun for students.
INOVASI APLIKASI BERNILAI ISLAMI PADA PENDIDIKAN ISLAM
Authors: Nurulqolbi Safira , Nabila Munif Mar'atun , Munawir
Published: August 2024

This research focuses on the usefulness and need for Islamic applications that can be used at home and aims to prevent the negative impacts of smartphone use. Seeing that the Islamic character of today's children is decreasing, this research is needed. This research uses a qualitative descriptive method by exploring social problems comprehensively and in depth. The data collection process uses literature study techniques on theories relevant to the research topic being conducted. And using narrative data analysis techniques by identifying and connecting texts to the phenomena being studied. The results show that the Marbel Muslim Kids application is an application that is suitable and needed for children today. Because it has many features of Islamic educational material which is presented in an attractive appearance. The success of using the application is also influenced by parental supervision in directing their children. Judging from reality, parents only hand over educational problems to teachers even though parents also play an important role in children's education, and a united collaboration between teachers and parents is needed to achieve educational success. It can be concluded that in this modern era, education must also reform but not abandon the integrity of the Qur'an and Hadith. Learning Islamic education can be made more interesting with interactive applications that can be used.
Saberes Didático-pedagógicos a partir de Modelos Didáticos Tridimensionais: em foco, o Ensino de Ciências
Authors: Junior Claudi Guerin , Cunha Fernando Icaro Jorge , Dinardi Ailton Jesus , Teodoro Paulo Vitor
Published: August 2024

O objetivo deste estudo é investigar as vantagens e desafios do emprego de modelos didáticos no Ensino de Ciências nos Anos Finais do Ensino Fundamental. A pesquisa adotou uma abordagem aplicada e exploratória, com uma metodologia qualitativa. Modelos didáticos foram elaborados para o Ensino de Ciências e apresentados a professores do Estado do Rio de Janeiro. A coleta de dados ocorreu por meio de questionários online, e os professores utilizaram os modelos em suas aulas remotas em junho de 2021, durante a pandemia de COVID-19. Os resultados foram baseados nas percepções de 5 professores sobre as potencialidades e limitações dos modelos no Ensino de Ciências e Biologia. Os resultados evidenciam que a introdução dos modelos didáticos nas aulas de Ciências teve um impacto positivo no processo de ensino e aprendizagem. Os professores destacaram a maior participação dos estudantes, o aumento do interesse e a melhoria na compreensão dos conteúdos. Além disso, os modelos contribuíram para abordar temas sensíveis, como educação sexual, de forma mais dinâmica e científica.
Inteligência Artificial e Inteligência Emocional: um debate para o presente e futuro da educação
Authors: Da Cruz Fraga Cristiano , Decarli Cecilia , Boll Cíntia Inês
Published: August 2024

Este artigo apresenta uma análise conceitual teórica da relação entre a Inteligência Artificial- IA e a Inteligência Emocional- IE, estabelecendo como base os tempos de cultura digital e a amplitude e acesso da IA por parte de estudantes e professores, que gera dúvidas aos docentes sobre seus benefícios ou malefícios em processos de ensino e aprendizagem. O objetivo do estudo foi descrever os conceitos de IA e IE e relacionar seu uso nos processos de ensino e aprendizagem, compreendendo a importância da inter-relação destas áreas para seu uso na educação e consequentemente no projeto de vida dos envolvidos. A redação envolve o diálogo entre diversos autores das duas áreas de conhecimento que se complementam a partir de uma análise dos autores, que se dá com eloquência e criticidade que o assunto merece e carece de atenção. A metodologia é uma revisão teórica da IA e da IE e sua inter-relação, onde se destacam a produção de sentidos, o uso da afetividade nos processos e geração de bem-estar social através do exposto, no sentido de que a IA esta posta e cabe a educação o desafio de propor usos que não enfoquem no econômico apenas, mas na criticidade e convivência em sociedade.
Concepções e práticas pedagógicas de professoras do ensino fundamental acerca da prevenção de doenças na infância
Authors: Bulhosa de Souza Michele , Foss de Zorzi Fernanda Cristina , Ribeiro Borges Luana , Loitzenbauer da Rocha Moreira Betina
Published: August 2024

Objetivou-se conhecer concepções e práticas pedagógicas de professoras sobre a prevenção de doenças na infância. Trata-se de um estudo qualitativo, exploratório e descritivo, do qual participaram 13 professoras de duas escolas públicas dos anos iniciais do Ensino Fundamental. Como instrumentos de coleta de dados foram utilizados questionário impresso e diário de campo. Os dados foram submetidos a análise conteúdo. As categorias de maior frequência indicaram que a prevenção de doenças na infância pode ser atrelada a evitar a doença; e a forma de realizar essa prevenção está relacionada a ações educativas. Quanto as temáticas abordadas na sala de aula destacaram-se alimentação e higiene.  A forma de abordagem do tema foi predominantemente dialógica, sendo que para realizar o planejamento foram consideradas a fase de desenvolvimento do estudante e as necessidades da turma. Como formas de aprimorar a abordagem da prevenção de doenças na escola as professoras citam ações intersetoriais e recursos pedagógicos atrativos. Como temática para realizar a formação continuada emergiu com maior frequência as doenças na infância de forma generalizada, e especificamente, apontou a saúde mental como tema. Portanto, as concepções e práticas pedagógicas das participantes deste estudo, relacionavam-se a evitar a doença por meio de ações educativas, sendo que para formação continuada a necessidade emergente foi a saúde mental na infância.
Entre encontros e desencontros: a afetividade na formação inicial em Pedagogia - reflexões a partir do relato de experiência de uma ex-bolsista do Pibid
Authors: Vilela Ribeiro da Silva Thais , Christian de Oliveira Pamplin Renata , De Oliveira Canedo-Júnior Ernesto
Published: August 2024

O objetivo do presente trabalho é refletir sobre relevância da afetividade no processo formativo da graduação em Pedagogia, a partir do relato de experiência de uma ex-pibidiana. A partir do relato, foram tecidas reflexões, junto de bibliografia especializada sobre a entrada dos estudantes no Ensino Superior, as especificidades das licenciaturas, a entrada da bolsista no Pibid e suas vivências afetivas dentro do Programa Institucional de Bolsa de Iniciação à Docência. O trabalho revelou a necessidade do tema da afetividade ser uma constante na formação dos futuros professores, em especial os pedagogos, pois estes são os que estão nas bases da Educação Básica e portanto precisam compreender todos os aspectos da formação cognitiva e afetiva que formam o que Wallon chama de pessoa completa.
Memórias da implementação e trajetória do Curso Técnico em Meio Ambiente do IF SUDESTE MG – Campus Rio Pomba
Authors: Martins  de Miranda Rosani , Gourete Duarte Edivânia Maria , Narvaes da Rocha Campos André
Published: August 2024

A conscientização ambiental e a abordagem de questões relacionadas ao meio ambiente não são apenas uma tendência global, mas uma necessidade urgente devido à insustentabilidade do modelo de desenvolvimento atual. O Instituto Federal Sudeste de Minas Gerais, Campus Rio Pomba, iniciou o curso Técnico em Meio Ambiente em 2008 com a intenção de formar profissionais qualificados para lidar com questões de gestão ambiental, conservação de recursos naturais e políticas públicas em nível municipal e regional. No entanto, observou-se recentemente uma redução no interesse pelo curso. Isso levanta a questão central: como egressos e estudantes percebem a importância do Curso Técnico em Meio Ambiente; como os egressos aplicam as habilidades e conhecimentos adquiridos no curso em suas vidas cotidianas e quais são os impactos do curso em suas trajetórias e no desenvolvimento local e regional. Este estudo tem como objetivo principal diagnosticar e evidenciar a importância do curso Técnico em Meio Ambiente, por meio do resgate de memórias de egressos e autoridades ambientais do município. O propósito é destacar a relevância tanto desses profissionais quanto do curso em si para promover o desenvolvimento sustentável do município e da região. Mesmo com a crescente conscientização ambiental e aumento da demanda por profissionais desta área, observamos uma diminuição na procura por certas modalidades do curso ao longo do tempo. Essa contradição nos instiga a refletir sobre como o público-alvo do curso percebe sua relevância, como os egressos aplicam seus conhecimentos na vida cotidiana e qual é o impacto desses profissionais no desenvolvimento local e regional. As informações obtidas proporcionaram uma compreensão mais profunda da trajetória deste curso, revelando sua natureza dinâmica e adaptável.
Promovendo a sensibilização sobre doping: explorando os conteúdos de aprendizagem a partir de uma intervenção pedagógica
Authors: Da Silva Matheus Palmeira , Bobadilha Lyvia Quevedo , Bedin Everton
Published: August 2024

Esse artigo objetiva apresentar e analisar uma intervenção didática que visou instigar em estudantes a mobilização dos conteúdos conceituais, procedimentais e atitudinais à luz de uma oficina pedagógica. Este estudo exploratório e de abordagem quali-quantitativa, usou a Análise de Conteúdo e o método indutivo-construtivo, a partir da observação e de questionário, para analisar a mobilização dos conteúdos conceituais, procedimentais e atitudinais de alunos de uma turma de Ensino Médio Técnico em Administração da rede pública de Curitba/PR. A intervenção, que consistiu na aplicação de uma Oficina Pedagógica e de um Escape Room sobre o doping, permitiu averiguar que a aprendizagem não ocorreu de forma homogênea para todos os alunos em todos os conteúdos de aprendizagem, e que alguns alunos sentiram dificuldade em realizar o Escape Room devido a obstáculos na interpretação do enigma e no domínio do conteúdo químico. Limitações e desdobramentos da pesquisa são apresentados.
Adoecimento docente: um estudo com professoras de uma rede municipal de educação
Authors: Padilha Thamirys , Carneiro Araujo Ludmilla , Venancio Bruno
Published: August 2024

Este estudo tem como objetivo entender quais os fatores que levaram professoras da Rede Municipal do interior de Minas Gerais a se afastarem das salas de aula e se submeterem à situação de ajuste funcional. Foram realizadas entrevistas com 12 professoras em situação de ajuste nas escolas públicas municipais. A pesquisa se caracteriza como qualitativa e como ferramenta de coleta de dados, foi utilizada a entrevista semiestruturada. Após a coleta de dados, foi realizada a análise e interpretação das informações. Ao término da realização da pesquisa, foi possível constatar que nessas professoras entrevistadas havia a presença de adoecimento tanto físico quanto mental. Calos nas cordas vocais foi um dos casos mais citados pelas docentes. Constatou-se que a carga horária contribui para o desgaste dessas profissionais. Conclui-se, a partir das análises, que as docentes precisam sentir-se mais seguras emocionalmente para exercer sua profissão e serem mais valorizadas. Portanto, ressalta-se a necessidade de olhar para as condições de trabalho do (a) professor (a), para o seu bem-estar e para a sua saúde, e não somente para os resultados de sua ação profissional.
Tendências e lacunas dos estudos de autismo no estado do Tocantins, Brasil
Authors: De Souza Cirlene Benvindo , Benvindo de Souza Marcelino , Gomes Araújo dos Santos Cirley , Da Silva Ivone Antonia , Evelio Samudio Cáceres Manuel
Published: August 2024

O Transtorno do Espectro Autista (TEA) é uma condição neurológica do desenvolvimento que afeta a comunicação, a interação social e o comportamento. Uma ampla gama de sintomas e níveis de gravidade podem ocorrer como déficits na comunicação, interação social, comportamentos repetitivos, interesse restrito e sensibilidades sensoriais. Nesse contexto, este estudo teve como objetivo realizar uma revisão sobre a produção científica do TEA no estado do Tocantins. O total de 20 artigos foram selecionados entre pesquisa de campo (n = 7) e revisões bibliográficas (n = 13). Os estudos de campo envolveram uma tendência para temáticas como a percepção de professores sobre o autismo, método fônico, caso clínico e diagnóstico sobre o cenário da educação. Já os artigos de revisão, os principais temas foram para a relação de uso de robôs e laboratórios remotos. A Universidade Federal do Tocantins foi a principal instituição de pesquisas voltada ao autismo no Tocantins. Finalmente, considerando o baixo número de pesquisas no estado e o aumento dos casos de autismo, realizar mais pesquisas na região será importante para compreender o cenário atual e aprimoramento da gestão de inclusão.
Semaphorin 3A promotes the long-term persistence of human SVF-derived microvascular networks in engineered grafts
Authors: Schwager Juan M. , Di Maggio Nunzia , Grosso Andrea , Rasadurai Abeelan , Minder Nadja , Hubbell Jeffrey A. , Kappos Elisabeth A. , Schaefer Dirk J. , Briquez Priscilla S. , Banfi Andrea , Burger Maximilian G.
Published: August 2024

Introduction

The stromal vascular fraction (SVF) of human adipose tissue is an attractive cell source for engineering grafts with intrinsic vascularization potential, as it is rich in vasculogenic progenitors. However, in order to maintain their functional perfusion it is important to promote the in vivo stabilization of newly assembled microvascular networks. We previously found that Semaphorin 3A (Sema3A) promotes the rapid stabilization of new blood vessels induced by VEGF overexpression in skeletal muscle. Here we investigated whether Sema3A could promote the assembly, connection to circulation and persistence of human SVF-derived microvascular networks in engineered grafts.

Methods

Recombinant Sema3A was engineered with a transglutaminase substrate sequence (TG-Sema3A) to allow cross-linking into fibrin hydrogels. Grafts were prepared with freshly isolated human SVF cells in fibrin hydrogels decorated with 0, 0.1 or 100 μg/ml TG-Sema3A and implanted subcutaneously in immune-deficient mice.

Results

After 1 week in vivo, the assembly of human-derived networks was similar in all conditions. The outer part of the grafts was populated by blood vessels of both human and mouse origin, which formed abundant hybrid structures within a common basal lamina. About 90% of human-derived blood vessels were functionally connected to the host circulation in all conditions. However, in the control samples human vessels were unstable. In fact, they significantly regressed by 6 weeks and could no longer be found by 12 weeks. In contrast, a low Sema3A dose (0.1 μg/ml) promoted further human vascular expansion by about 2-fold at 6 weeks and protected them from regression until 12 weeks. From a mechanistic point of view, the stabilization of SVF-derived vessels by 0.1 μg/ml of Sema3A correlated with the recruitment of a specific population of monocytes expressing its receptor Neuropilin-1.

Discussion

In conclusion, Sema3A is a potent stimulator of in vivo long-term persistence of microvascular networks derived from human SVF. Therefore, decoration of matrices with Sema3a can be envisioned to promote the functional support of tissue engineered grafts.