bluuebunny/crossref_metadata_2025 huggingface dataset:
Association of Anisocytosis with Markers of Immune Activation and Exhaustion in Treated HIV
Authors: Al-Kindi Sadeer G. , Zidar David A. , McComsey Grace A. , Longenecker Chris T.
Published: May 2017

Background: Treated HIV infection is associated with heightened inflammation which can contribute to increased risk of cardiovascular disease (CVD). We have previously shown that anisocytosis, as measured by red cell distribution width (RDW), is independently associated with prevalent CVD in people living with HIV (PLHIV). In this study, we sought to identify immune correlates of RDW in PLHIV receiving antiretroviral therapy.Methods: We performed a cross-sectional and longitudinal analysis of 147 virally-suppressed PLHIV, who had LDL <130 mg/dL and evidence of heightened inflammation, in a randomized trial of statin therapy. A complete blood count and biomarkers of inflammation and immune activation/exhaustion were measured in peripheral blood at entry and after 24 and 48 weeks. Associations with RDW were estimated using linear regression and linear mixed models.Results: The median age (IQR) for the cohort at enrollment was 46 (40–53) years; 78% were male and 68% were African American. The median RDW for the cohort was 13.4% (12.9–14.0). Compared with the lowest RDW tertile, patients in the highest tertile were less likely to be male, and more likely to be African American, have lower hemoglobin, lower mean corpuscular volume, and higher platelet counts (all P<0.05). At baseline, RDW weakly correlated with C-reactive protein (r=0.196), d-dimer (r=0.214), fibrinogen (r=0.192), interleukin-6 (r=0.257), CD4+DR+38+ T cells (r=0.195), and CD4+PD1+ T cells (r=0.227), all P<0.05. Only IL-6, CD4+38+DR+ T cells, and CD4+PD1+ T_cells remained associated after adjustment for clinical factors known to affect RDW in the general population. Over 48 weeks, RDW did not change and there was no significant effect of statin (P=0.45). After adjustment for clinical parameters, RDW remained positively associated with CD4+38+DR+ and CD4+PD1+ T cells across all time points (P=0.05).Conclusion: In this population of treated HIV+ subjects, anisocytosis was associated with biomarkers of inflammation and T-cell activation/exhaustion over time and independent of clinical confounders. Therefore, RDW may be a useful prognostic biomarker of cardiovascular risk that partially reflects chronic inflammation and immune exhaustion in PLHIV receiving antiretroviral therapy.
Como as âncoras de carreira de Edgar Schein influenciaram na escolha da carreira feita por alunos de uma universidade do interior de São Paulo
Authors: Reis Thompson Augusto , Leite Sandra Toledo , Graziano Graziela Oeste , Osvaldo Yeda Cirera
Published: May 2017

Este estudo tem como objetivo mostrar as âncoras de carreiras mais presentes dentro de cada geração. As amostras de pesquisas foram coletadas entre estudantes de uma universidade do interior de São Paulo e compreendem as gerações X, Y e Z. O grupo pesquisado foi de 233 alunos do quinto e sétimo semestre do curso de Administração e houve um retorno de 100% dos questionários enviados. A aplicação da pesquisa se deu entre os meses de abril e junho, os pesquisados foram encaminhados ao laboratório de informática da instituição de ensino onde foram preenchidos os questionários e suas respostas foram encaminhadas por e-mail. A pesquisa também aponta o gênero sexual dos entrevistados e é do tipo descritiva-analítica, foi utilizado um questionário fechado contendo quarenta perguntas. É importante analisar as âncoras mais presentes em cada geração e se há diferenças entre os gêneros sexuais, pois isto pode contribuir para um melhor entendimento do desenvolvimento das carreiras e também pode ajudar na diminuição de conflitos entre líderes e colaboradores, uma vez que o entendimento das âncoras em confronto com as características de cada geração leva a melhores maneiras de interação entre líderes e colaboradores.
Experiential dimensions and their influence on behavioral intentions within the context of nature-based tourism
Authors: Sotiriadis Marios
Published: May 2017

Purpose – This paper aims at investigating the customers’ experience in nature-based attractions and its influence on post consumption behavior. Design – The study uses two theoretical frameworks (experience economy and behavioural intentions) to investigate the determining dimensions of the wildlife experience to customer satisfaction, and the relationships between the wildlife experience and the behavioural intentions. Approach – The research develops an explanatory framework of consumer experience that measures the four dimensions and their relative influence on satisfaction, perceived service quality and behavioral intentions. Methodology – The proposed research framework was empirically tested by implying a quantitative research and the technique of convenience sampling to customers of Game Reserves in Republic of South Africa. Findings – The results indicate that the experience framework constitutes a valid tool for the study of wildlife experiences. In the context of nature-based tourism the experiential dimensions which influence the perceived service quality and customers’ satisfaction are escapism and esthetics. There is also a strong correlation between wildlife experience and post consumption behavioural intentions, especially for word-of-mouth and repurchase intention. Originality – The research extends existing theory by incorporating new elements and empirically investigating them within a new context. It is the first empirical study that investigates the experiential dimensions within the context of nature-based tourism and customers’ behavioural intentions. It develops an explanatory framework of customer experience that measures the four dimensions, their relationship with experience outcomes (satisfaction and perceived service quality) and their relative influence on behavioural intentions.
QUANDO O BRASIL FICCIONAL FAZ PENSAR O BRASIL REAL. Como a crítica entra nessa história?
Authors: Carlos Magno Maria Ignês
Published: May 2017

Esse texto é parte da pesquisa: A telenovela brasileira sob os olhos da crítica nos anos 1970. Considerando a teleficção como objeto de pesquisa dado seu diálogo constante com a realidade brasileira locus dessa relação, a proposta desse artigo é compreender no âmbito da linguagem crítica que relações podemos estabelecer entre a crítica de telenovela com as discussões históricas que ocorriam no Brasil nos anos 1970. A crítica é entendida como parte do processo social e atividade teórica que ao veicular os pensamentos e reflexões sobre televisão e telenovela, exerce uma função cultural e histórica. Para desenvolver o estudo sobre os diálogos existentes entre críticas veiculadas na mídia impressa e as temáticas históricas das telenovelas, escolhi a novela Os Ossos do Barão (1973/74) de Jorge Andrade e as críticas de Helena Silveira e Artur da Távola publicadas nos jornais Folha de S. Paulo e no jornal O Globo.
TRABALHADORAS DO SEXO NA SÉRIE DA HBO, O NEGÓCIO: Representações e a Prostituição de Luxo
Authors: Desidério Plábio Marcos Martins , Duarte Lailson
Published: May 2017

Neste trabalho buscamos compreender as representações da prostituição de luxo, a partir de uma produção televisiva: a série O Negócio, produzida pela HBO. Esta série suscita questões sobre as trabalhadoras do sexo, e, portanto, buscamos analisar alguns discursos e representações dessas mulheres como garotas de programa numa série de televisão. Muitas dessas representações quando se referem a prostituição de luxo procuram evidenciar uma dimensão lúdica, hedonista, sofisticada e consumista, sem, no entanto, questionar as muitas questões que cercam essa prática social.
JORNALISMO AUTOMATIZADO, GERAÇÃO DE LINGUAGEM NATURAL E A LÓGICA DO BOM SUFICIENTE
Authors: Carreira Krishma , Squirra Sebastião
Published: May 2017

A explosão de dados digitais e o avanço do campo da Inteligência Artificial permitiram o surgimento de algoritmos capazes de redigir e distribuir automaticamente notícias jornalísticas com rapidez e de forma customizada. A automatizacão da produção de narrativas entrega textos básicos, objetivos e sem sofisticação, formatando a função de jornalistas e contribui para a ampliação da chamada "bolha de filtros" definida por Eli Pariser.  Neste texto, procuramos demonstrar que ao adotar a automação, redações nos Estados Unidos, Europa e China passaram a usar a lógica do bom suficiente, demonstrada por Robert Capps. Ou seja, a automatização da elaboração de notícias pode estar sendo adotada unicamente por seu caráter "industrial" e pelo custo radicalmente reduzido, não priorizando a diversificação, a cultura e a qualidade humana dos relatos. As reflexões centram-se em pesquisa bibliográfica de caráter exploratório e interdisciplinar, a partir da abordagem da Teoria Ator-Rede.
ELIAS MACHADO DISCUTE A FORMAÇÃO DO DOCENTE E DO ESTUDANTE DE JORNALISMO NA CONTEMPORANEIDADE
Authors: Gehlen Marco Antônio , Reino Lucas Santiago Arraes , Bueno Thaisa Cristina
Published: May 2017

Doutor em Jornalismo pela Universidade Autônoma de Barcelona (Espanha), professor da Universidade Federal de Santa Catarina(UFSC) e coordenador do Laboratório de Pesquisa Aplicada em Jornalismo Digital, o jornalista Elias Machado é uma referência nacional quando o assunto é o ensino de Jornalismo. Consultor Ad Hoc (CAPES), (CNPq), (SBPJOR), (COMPÓS), (INTERCOM) e (FNPJ), Machado tem vasta experiência nas áreas de Teorias do Jornalismo, Metodologias de Pesquisa, Jornalismo Digital e Impresso. 
Nesta entrevista, ele discute a deficiências da educação na área em faculdades públicas e privadas e alerta: "Temos que garantir que o aluno fique menos tempo em sala de aula. Nós temos que racionalizar e integrar as disciplinas para que sobre mais tempo para pesquisa e extensão".
Ele aproveita a conversa para debater, ainda, as implicações que as novas diretrizes do curso, discutidas e implementas em todas as universidades do país, podem acarretar à carreira, bem como os dilemas sobre prática e teoria, produção laboratorial e formação de professores, entre outras dicotomias que afligem quem trabalha com comunicação social, seja no mercado, na pesquisa ou na sala de aula. Além disso, Machado critica nesse espaço de reflexão, as pesquisas que fazem uma mera análise de dados e incentiva os estudos aplicados. " porque a crítica pela crítica não resolve o problema da demanda social". Assumidamente um pesquisador polêmico e provocador, justifica: "se eu estudei e me preparei foi para enfrentar os problemas. Não tem sentido eu chegar num lugar e dizer mais do mesmo, as pessoas não precisam ouvir mais do mesmo".
RESPONSIBILITY OF THE STATE IN SOLVING CONFLICT AMONG RELIGIOUS PEOPLE (RESEARCH CONDUCTED IN CENTRAL JAVA
Authors: Fidiyani Rini
Published: May 2017

Freedom of choosing/believing religion/credo is a right guaranteed by the state (Article 28 E point (2) UUD 1945). Nonetheless, that freedom has become a mere myth since the state involves in violation against the freedom of religion/credo towards the minorities in solving their conflict in several places, particularly in Central Java. This research investigates the responsibility of the state towards that conflict using normative and empiric law approach as problem-solving methods. The result of this research  shows several things. First, there found unfairness in the state in solving conflict amongst religious people; Second, there found an involvement from certain religion follower (which supported by the state servant) in conflict amongst  religious people and in other violation against the freedom of religion; Third, it has not been unclear the acts of responsibilty from the state about their behaviours; and Fourth, there found no any way for the victims towards state’s behavior, to claim their rights. To solve the problem, it needs to be arranged in a normative or politic way about how the state takes responsible in dealing with conflict amongst religious people, either as a mediator or as the perpretator of discrimination or the offender of freedom of religion. Besides, we need also to find some ways for the victim to defend their rights and their freedom.Key words: freedom of religion, conflict, discrimination, responsibility of the state.
SETTING OF PLANTATION LAND AREA LIMITATION BASED ON SOCIAL FUNCTION PRINCIPLES OF LAND CULTIVATION RIGHTS TO REALIZE SOCIAL WELFARE-PROMOTING PLANTATION
Authors: Karjoko Lego
Published: May 2017

The existence of large plantations in Indonesia has proven the failure of individualism value to uphold agrarian justice. This study aims to examine regulations regarding to the land ownership which contradicts with social function principles of Land Cultivation Rights (LCR) and provide recommendation for setting the land ownership which can realize land utilization for plantation ideally. This study employs normative legal research method by statute and conceptual approach. The legal materials were analyzed by inductive, deductive and interpretative syllogism. The results of this research are as follows. First, regulations on Site Permit, Plantation Operation Permit and Release of Forest Area for Plantation based on utilitarian justice and concentrative land ownership are not in accordance with social function principles of Land Cultivation Rights (LCR). Second, the setting of maximum ownership for plantation companies should be based on their type of plants and given fully assets that enable the plantation companies to use the land optimally.Keywords: Land Cultivation Rights, cultivation land area, people’s welfare
URGENSI PENGATURAN PERLINDUNGAN PENGUNGSI LINGKUNGAN AKIBAT PERUBAHAN IKLIM DALAM PERSPEKTIF HUKUM INTERNASIONAL
Authors: Wartini Sri
Published: May 2017

Climate change refugess is caused by sudden impact disasters  and slow onset disasters because of climate change. The climate change refugess is not included as the refugees which are regulated under the Refugees Convention 1951, since the climate refugees are not caused by persecution. Thus, it is necessary to find out a solution based on international law to provide legal protection to the climate change refugees. The aim of the research is to analyse comprehensively the urgency of legal protection to the climate refugees and to find out an appropriate legal protection fo them.                                             The fundings of the research namely : First,  there is a legal lacuna to  the protection of climate change refugees ; second, The need to regulate the legal protection to the climate change refugees, since they become the victims of climate change.Key Words : Climate change refugees, global warming and urgency
TESTE ORCID
Authors: Sant'Anna José Carlos
Published: May 2017

TESTE ORCID
Schooling and subversions of gender
Authors: Dias Alfrancio Ferreira , Cardoso Helma de Melo , Santos Adriana Lohanna dos , Menezes Carlos André Araújo , Rios Pedro Paulo Souza
Published: May 2017

The aim of this essay is to discuss bodies and discourses that question and confront gender norms and all possibilities of control of bodies in formative institutions. In order to do so, we analyzed three field research scenes, performed in different times and spaces. We show that they take place in the formative practices and spaces, there are several areas of subversion to norms and we face the control of bodies, as well as to show that these are dispute places, that in our research we do not generally privilege the discourses which subvert.
The Use of Robomind Application in Problem Based Learning Model to Enhance the Student’s Understanding on the Conceptual Programming Algorithm.
Authors: Nofitasari Anggun , Yuana Rosihan Ari , Maryono Dwi
Published: May 2017

The purpose of this research was to improve understanding of basic programming algorithms concept of class X TKJ 1 SMK N 1 Banyudono on Basic Programming lesson using robomind application through Problem Based Learning model. This research was a Classroom Action Research, with research subjects were 33 students of class X TKJ 1 SMK N 1 Banyudono. This research was started by identifying the problems occured in the classroom. Then, we designed actions to solve the problem in a cycle of actions. In this research, the actions were done in two cycles. Each cycle consists of planning, implementation, observation and reflection. Data was collected by observation of the learning activities in the classroom and comprehension tests after each cycle. Analysis of the data was performed using quantitative and qualitative analysis interactive technique. The results showed that the implementation of the Problem Based Learning model using media assistance robomind applications could enhance students' understanding of the program algorithm. It is shown by the completeness of comprehension tests on pre-cycle 37.5%, 44.8% in the first cycle, and 93.3% in the second cycle.

 

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
PEMBAHARUAN KEBIJAKAN PIDANA KEJAHATAN PERDAGANGAN ORANG (STUDI DI WILAYAH PERBATASAN KALIMANTAN BARAT-SARAWAK)
Authors: Hasyim Azizurrahman Syarif
Published: May 2017

Abstract

Law. 21 of 2007 already contained the formulation of the Crime of Trafficking in Persons, but criminal law policies contained insufficient to combat human trafficking in West Kalimantan-Sarawak border, because it has not been formulated based on the modus operandi and the prediction of the development of the crime of trafficking in persons in the border region, so it needs to be done renewal.

Keywords: Trafficking Crime, criminal law policy, criminal law Updates

Abstrak

UU No. 21 Tahun 2007 telah memuat rumusan Tindak Pidana Perdagangan orang,  namun kebijakan hukum pidana yang dimuat belum memadai untuk memberantas perdagangan orang di wilayah perbatasan Kalimantan Barat-Sarawak, karena belum diformulasikan berdasarkan modus operandi dan prediksi perkembangan kejahatan perdagangan orang di wilayah perbatasan, sehingga perlu dilakukan pembaharuan.

Kata Kunci: Kejahatan Perdagangan orang, Kebijakan hukum pidana, Pembaharuan hukum pidana
KAJIAN FILOSOFIS TENTANG KONSEP KEADILAN DARI PEMIKIRAN KLASIK SAMPAI PEMIKIRAN MODERN
Authors: Johan Nasution Bahder
Published: May 2017

Abstract

Justice, since the first issue, has been the subject of study both among philosophers and among theologians, politicians and thinkers or legal experts. However, if there are questions about justice, could not be determined what measures are used to determine something is fair or not. Various answers about justice usually never or rarely satisfying so that continues to be debated, so it can be concluded that the various formulations of justice is a relative statement. This issue ultimately encourages many people to take a shortcut by submitting formulation of justice to the legislators and judges who will formulate it based on their own considerations.

Keywords : Philosophy, justice

Abstrak

Masalah keadilan sejak dahulu telah menjadi bahan kajian baik dikalangan ahli filsafat maupun dikalangan agamawan, politikus maupun para pemikir atau ahli hukum. Pertanyaan tetang keadilan, tidak bisa ditentukan ukuran yang digunakan untuk menentukan sesuatu itu adil atau tidak. Berbagai jawaban tentang keadilan biasanya tidak pernah atau jarang yang memuaskan sehingga terus menjadi perdebatan, dengan demikian rumusan mengenai keadilan merupakan rumusan yang relatif. Persoalan ini pada akhirnya mendorong banyak kalangan untuk mengambil jalan pintas dengan menyerahkan perumusan keadilan kepada pembentuk undang-undang dan hakim yang akan merumuskannya berdasarkan pertimbangan mereka sendiri.

Keywords: Kajian Filosofis, Konsep Keadilan
Mourning Becomes Electra: Morbid Psychology under the "Mask"
Authors: Yijin Gong
Published: May 2017

By giving his main characters all with the "life-like mask", Eugene O'Neill in his play Mourning Becomes Electra aims to reveal the morbid psychology behind that people at that time were facing. O'Neill deepens the tragic effect of excessively emotional self-restraint by intentionally making the conflict happen between family members in a puritanical family, and further making it become a family's doomed and repeated fate. O'Neill presents the awkward situation but he fails to presents the way out; he indeed leaves the remedy to his audience.
Evaluation of Islamic Management of Beef Cattle Development program of Lembaga Mandiri Mengakar Masyarakat: Pondok pesantren al Mawaddah Warrahmah Kolaka - Sulawesi Tenggara Case
Authors: Zakariah Muhammad Askari , Zakariah Muhammad
Published: May 2017

The purpose of the research were to analyze the level of achievement of islamic management on beef cattle development program of Lembaga Mandiri Mengakar Masyarakat in Pondok Pesantren Al Mawaddah Warrahmah Kolaka-Sulawesi Tenggara Case. The research was conducted January 2012-January 2016. Independent agencies are Rooted in the Community in Pondok Pesantren Al Mawaddah Warrahmah as respondent were selected. The data were statistically analyzed by descriptive analysis to analyze the achievement of the program. The result showed that the achievement level of amount of beef was high in periode 2012, 2013, 2014, and 2015 (75, 78.5, 75, and 88.88 % respectively), number of farmer was low (100, 100, 100, and 57.4% respectively) from its target, profit sharing was high (Rp.10.425.000, Rp.16.700.000, Rp.17.500.000, dan Rp.21.025.000).). That can be concluded that program of independent agencies are rooted in the community (LM3) in Pondok Pesantren Al Mawaddah Warrahmah case is effective.
Commodification of Religious Tradition: Critical Study on Religious Tradition Tourism Haul at Pasar Kliwon Surakarta
Authors: Setiawan Muhammad Ferri
Published: May 2017

The policy on tourism development program of Surakarta especially on the calendar of the event takes advantage from religious tradition as tourism commodity. The purpose of this study is to describe the religious tradition haul, the programs by the tourism department of Surakarta, and how commodification through a well implemented marketing communications process, messaging, and other media, as well as responses from the audience regarding the marketing of haul tradition in general toward creating a leading tourism object. Haul which is a tradition for commemorating the death of clerics (ulama) who are followed by some local communities in Surakarta, especially those in Pasar Kliwon Regency, is utilized in tourism. Through critical study, the cultural values that are supposed to be preserved, changed into marketing values to attract visitors. The used media are the advertisement and the calendar of events. The local community gain advantages economically from this policy, but they object to it socio-culturally. Meanwhile, the tourists are generally interested in haul tradition.
Religious Tourism in the Perspective of Kendal Society
Authors: Lutfiyah Lutfiyah
Published: May 2017

Ziarah qubur is the sunnah worship by Prophet Muhammad, either a family grave or the clergy, auliya’, and shalaf al-Salih who have died. The behavior of ziarah qubur is interested to be studied because it seems to be a trend for people who have interest in popolar culture. Popular culture is often regarded as a product or cultural practices with low taste. This refers to the view that popular culture is a commercial culture as a result of mass production and industrialization so that it can be a lifestyle. This study aimed to answer the extent to which the public's understanding of the ziarah qubur in Kendal regency. Through interviews and observation, this qualitative research led to the conclusion that ziarah qubur became a tradition, entertainment and ziarah motivation. The results of this research could develop in a more diverse results if developed on a broader subject.
The Methodology of Clinical Studies Used by the FDA for Approval of High-Risk Orthopaedic Devices
Authors: Barker Jordan P. , Simon Stephen D. , Dubin Jonathan
Published: May 2017

Background:

The purpose of this investigation was to examine the methodology of clinical trials used by the U.S. Food and Drug Administration (FDA) to determine the safety and effectiveness of high-risk orthopaedic devices approved between 2001 and 2015.

Methods:

Utilizing the FDA’s online public database, this systematic review audited study design and methodological variables intended to minimize bias and confounding. An additional analysis of blinding as well as the Checklist to Evaluate a Report of a Nonpharmacological Trial (CLEAR NPT) was applied to the randomized controlled trials (RCTs).

Results:

Of the 49 studies, 46 (94%) were prospective and 37 (76%) were randomized. Forty-seven (96%) of the studies were controlled in some form. Of 35 studies that reported it, blinding was utilized in 21 (60%), of which 8 (38%) were reported as single-blinded and 13 (62%) were reported as double-blinded. Of the 37 RCTs, outcome assessors were clearly blinded in 6 (16%), whereas 15 (41%) were deemed impossible to blind as implants could be readily discerned on imaging. When the CLEAR NPT was applied to the 37 RCTs, >70% of studies were deemed “unclear” in describing generation of allocation sequences, treatment allocation concealment, and adequate blinding of participants and outcome assessors.

Conclusions:

This study manifests the highly variable reporting and strength of clinical research methodology accepted by the FDA to approve high-risk orthopaedic devices.
Strategies to Minimize Blood Loss and Transfusion in Pediatric Spine Surgery
Authors: O’Donnell Courtney , Michael Nicole , Bloch Nikki , Erickson Mark , Garg Sumeet
Published: May 2017

* Definitive correction of pediatric spinal deformities can result in considerable blood loss, operative time, cost, and need for allogenic blood transfusion.

* Numerous intraoperative strategies are utilized by surgeons and anesthesiologists to minimize blood loss through conservation or transfusion.

* With the use of modern perioperative blood-conserving techniques, blood loss and blood transfusion rates have been reduced substantially in pediatric patients treated operatively for spinal deformities.
An investigation and analysis on the epidemic of varicella in a university of Weifang in China
Authors: Shao Lijun , Fang Lei , Qi Xiao , Wu Xueqian , Niu Guoyu
Published: May 2017

Objective  To investigate the reasons and understand the epidemiological features of the cluster outbreak of varicella in university, and provide scientific basis for preventing varicella. Methods The cases were diagnosed by clinical manifestations and serological test. An epidemiological survey was carried out using case study questionnaire combined with serological test of close contacts. Results This outbreak lasted 45 days from Oct 15th to Nov 30th, four cases were accumulated involving one major and two classes, with the incidence rate of 3.7% (4/107). All patients were male adult students. The serological test results showed that the VZV-IgM antibody was positive in acute phase sera of 4 patients, and the level of VZV-IgG antibody in the recovery phase sera was 4 times higher than that in the acute phase. One of 45 contacts was VZV-IgM positive while 4of 45 contacts were VZV-IgG positive. Conclusion This cluster varicella epidemic was caused by VZV. Close contact may be the risk factor. The school should strengthen the management of infectious diseases, and strictly enforce the epidemic registration system. Effective isolation measures and publicity works were also needed. Besides, it were promoted that the census of varicella antibodies in healthy population and vaccination.
Frecuencia de sobrecarga de hierro en pacientes con enfermedades hematológicas
Authors: Flores-Jiménez Juan Antonio , Saldaña-Vázquez Roxana , Villarreal-Martínez Laura , Gutiérrez-Aguirre César Homero , Jaime-Pérez José Carlos , Cantú-Rodríguez Olga Graciela , González-Llano Oscar , Gómez-Almaguer David
Published: May 2017

Señor editor: La sobrecarga de hie­rro (SH) es un problema de salud pública. La hemosiderosis asociada con la transfusión de eritrocitos produce toxicidad, disfunción tisular y susceptibilidad a infecciones; en general son daños mediados a través de la generación de radicales libres…
Incretins and Lipid Metabolism
Authors: Tsimihodimos Vasilis , Elisaf Moses
Published: May 2017

Background:

Recent findings indicate that incretin hormones and incretin-based
therapies may affect the metabolism of lipoproteins, although the corresponding mechanisms
are not clearly defined.

Objective:

To summarize the available data on the mechanisms linking incretins with the
characteristics of serum lipoproteins and discuss the clinical implications of these relationships.

Methods:

PubMed was searched using the terms “incretins”, “GLP-1”, “GIP” and “lipids”,
“dyslipidemia”, “triglycerides”, “apolipoprotein B48”. All articles published in the English
language until June 2016 were assessed and the relevant information is presented here.

Results:

GLP-1, and therapies that increase its activity, exert a beneficial effect on lipoprotein
metabolism that is translated in a reduction in the fasting and postprandial concentration of
triglycerides and a small improvement in the concentration and function of HDLs. In addition,
a shift towards larger, less atherogenic particles usually follows the administration of GLP-1
receptor agonists. The mechanisms that underlie these changes involve a direct effect of GLP-
1 on the hepatic and intestinal production of triglyceride-rich lipoproteins, the GLP-1 induced
increase in the production and function of insulin, the activation of specific areas of central
nervous system as well as the increase in the peripheral utilization of triglycerides for energy
production. On the other hand, GLP-2 increases the absorption of dietary fat and the production
of triglyceride-rich lipoproteins while the role of GIP on lipid metabolism remains indeterminate.

Conclusion:

GLP-1 and incretin-based therapies favorably affect lipid metabolism. These effects
may contribute to the beneficial effects of incretin-based therapies on atherosclerosis and
fatty liver disease.
Impact workshop desain pembelajaran oleh center for teaching staff development (CTSD) terhadap peningkatan profesionalisme dosen
Authors: Suryana Yayan , Aryani Sekar Ayu , Irsyadunnas I.
Published: May 2017

Pembelajaran di perguruan tinggi adalah pembelajaran orang dewasa yang mengantarkan pembelajar pada kehidupan nyata di masyarakat. Oleh karena itu, seyogianya pembelajaran dirancang untuk membekali pembelajar berkarya atau bekerja di dunia nyata dan dirancang sebagai adult learning. Secara umum alumni Workshop Desain Pembelajaran di Perguruan Tinggi oleh Center For Teaching Staff Development (CTSD) mengungkapkan bahwa workshop itu menyenangkan, inspiratif, dan membantu mereka untuk meningkatkan profesionalisme dosen, terutama di bidang paedagogik. Secara umum alumni workshop, pemangku kepentingan/pengguna maupun fasilitator mengharap CTSD ke depan lebih meningkatkan kiprah dan keterlibatannya di UIN Sunan Kalijaga.Kata kunci: pembelajaran, adult learning, profesionalisme THE IMPACT OF LEARNING DESIGN WORKSHOP CONDUCTED BY CENTER FOR TEACHING STAFF DEVELOPMENT (CTSD) ON THE IMPROVEMENT OF TEACHING PROFESSIONALISMAbstractLearning in college is learning that sends adult learners in real life in the community. Therefore, learning should be designed to equip learners take part or work in the real world and is designed as adult learning. The former participants of Learning Design Workshop in Higher Educational Institution conducted by Center for Teaching Staff Development (CTSD) revealed that the workshop was fun, inspiring, and helping them to improve the professionalism of teachers, especially in the field of pedagogy. Generally, the alumni of the workshop, stakeholders/users, and trainers hope that CTSD can improve its involvement further in UIN Sunan Kalijaga.Keywords:learning, adult learning, profesionalisme
Pembelajaran fisika berbasis web enhanced course: mengembangkan web-logs pembelajaran fisika dasar I
Authors: Asyhari Ardian , Diani Rahma
Published: May 2017

Penelitian ini bertujuan untuk mengembangkan Web-blogs dengan metode R&D prosedur 4D (define, design, develop, disseminate) yang dapat mendukung Web Enhanced Course (WEC) agar menunjang pembelajaran Fisika Dasar 1 materi Gerak Dua Dimensi pada mahasiswa Program Studi Pendidikan Fisika UIN Raden Intan Lampung, dan mengetahui kriteria penilaian melalui validasi produk dari ahli desain instruksional, ahli media pembelajaran, dan ahli web designer. Serta mengetahui tanggapan mahasiswa terkait kemenarikan produk dan kemudahan penggunaan dari produk yang dikembangkan. Spesifikasi pada WEC yang dikembangkan menekankan pada web yang memungkinkan terjadinya komunikasi interaktif antara dosen dan mahasiswa, baik secara individu maupun kelompok, serta dapat menjadi alternatif belajar secara online. Setelah divalidasi oleh ahli desain instruksional, ahli media pembelajaran, dan ahli website designer, didapatkan nilai dengan kriteria “sangat baik” dan memperoleh nilai dengan kriteria “sangat baik” setelah dilakukan uji coba terbatas (N=15) dan uji coba diperluas (N=90) dalam hal kemenarikan desain dan kemudahan penggunaan produk awal dan produk akhir dari WEC yang dikembangkan.Kata kunci: R&D, web enhanced course, fisika dasar I PHYSICS LEARNING BASED ON WEB ENHANCED COURSE: DEVELOPING WEB-LOGS TO SUPPORT PHYSICS I COURSEAbstractThis research aims to (1) develop a Web-blogs by the method of R & D procedures 4D (define, design, develop, disseminate) that can support Web Enhanced Course (WEC) to help to learn Physics 1 material Motion Two-Dimensional student department of physics education UIN Raden Intan Lampung. (2) Know the assessment criteria through product validation from instructional design experts, learning media experts, and web designers expert. Moreover, (3) knowing the students' responses related to the attractiveness of the product and the ease of use of the developed product. Specifications on the WEC developed an emphasis on the web that enables interactive communication between faculty and students, either individually or in groups, and can be an alternative to online learning. After being validated by an instructional design expert, an instructional media expert, and a website designer. A score of "excellent" criteria was obtained and scored with "excellent" criteria after a limited trial (N = 15) and an expanded trial (N = 90) regarding design attractiveness and ease of use of the initial product and end product of the developed WEC.Keywords: R & D, Web Enhanced Course, Physics I
PENGARUH INTERAKSI DALAM PEER GROUP TERHADAP PERILAKU CYBERBULLYING SISWA
Authors: Budiarti Arsa Ilmi
Published: May 2017

Seiring dengan teknologi, informasi dan komunikasi yang semakin modern, muncul fenomena baru yaitu cyberbullying sebagai dampak negatif atas perkembangan tersebut. Seringkali sifat tanpa-batas dan anonimitas dalam dunia maya seakan menjadi faktor yang tidak bisa terhindarkan dalam mendukung cyberbullying. Dalam artikel ini, penulis melihat faktor lain dengan asumsi bahwa semakin positif interaksi dalam peer group dan semakin rendah pengalaman bullying serta pengetahuan siswa tentang peraturan sekolah terkait kekerasan maka semakin rendah perilaku cyberbullying. Unit analisis penelitian ini adalah individu yaitu siswa Sekolah Menengah Atas di Jakarta. Data penelitian diperoleh dari hasil survei kuisioner terhadap 336 responden. Hasil penelitian menunjukkan bahwa diantara ketiga variabel yang digunakan, interaksi dalam peer group menjadi variabel yang paling berpengaruh terhadap perilaku cyberbullying siswa. Hal ini menunjukkan bahwa teman sebaya melalui interaksinya memiliki pengaruh yang cukup kuat dalam mendukung perilaku cyberbullying siswa.
FORUM INTERNET SEBAGAI CYBER PUBLIC SPACE: ANALISA KOMPARASI KASKUS, ADSENSE-ID DAN SEMPROT.COM
Authors: Roikan Roikan
Published: May 2017

Penggunaan internet di Indonesia berdasarkan pengamatan saya mulai marak pada era akhir tahun 90-an dengan munculnya jasa warung internet (warnet). Berbagai kemudahan ditawarkan dari internet, dari mesin pencarian, surat elektronik (email), berita, jejaring sosial sampai forum. Forum dalam internet menjadi media penyampaian berita, diskusi sampai penyajian informasi dalam lingkup bidang khusus yang didominasi oleh interaksi yang intensif di antara anggotanya. Artikel ini mendiskusikan peranan forum cyber di internet sebagai ruang publik dengan menggunakan pendekatan antropologi visual dan antropologi media massa. Artikel ini juga memfokuskan diri pada fenomena komunitas-komunitas cyber dan interaksi mereka di dalam dunia virtual seperti KASKUS, Adsense-Id dan Semprot.com. Metode Penelitian yang digunakan di dalam artikel ini adalah analisis forum internet dengan menggunakan analisis partisipasi, analisis isi, dan analisis tema.
Tatakelola Inovatif dalam Penanganan Masyarakat Rentan Perkotaan: Belajar dari Kewiralembagaan Yayasan Girlan Nusantara
Authors: Astuti Eka Zuni Lusi
Published: May 2017

Keberadaan masyarakat rentan menjadi perhatian dalam pembangunan perkotaan. Program-program penanganan masyarakat rentan berbasis negara belum dapat mengatasi persoalan tersebut. Di sisi lain, aktor dari akar rumput turun tangan melalui berbagai institusi inovatif berbasis masyarakat. Yayasan Girlan Nusantara merupakan salah satu institusi inovatif yang berkiprah dalam penanganan masyarakat rentan di Yogyakarta. Menggunakan pendekatan institutional entrepreneurship (kewiralembagaan), penelitian ini bertujuan untuk mengelaborasi kiprah inovatifYayasan Girlan Nusantara dalam penanganan masyarakat rentan. Penelitian ini menggunakan metode penelitian kualitatif dengan teknik pengumpulan data berupa observasi dan wawancara mendalam dan interpretasi data menggunakan metode kualitatif. Temuan dari penelitian ini bahwa actor (wiralembagawan) dapat menentukan keberhasilan institusi inovatif. Tatakelola inovatif dapat berjalan efektif karena wiralembagawan memiliki modal sumber daya manusia, modal sosial, dan keterampilan sosial.
Kelompok Rentan dalam Pembangunan Kawasan Kota Bandara di Kulon Progo: Studi Kasus New Yogyakarta International Aiport (NYIA)
Authors: Kustiningsih Wahyu
Published: May 2017

Pembangunan bandara merupakan infrastruktur transportasi yang dinilai strategis dalam upaya peningkatan perekonomian lokal. Salah satunya pembangunan bandara baru di Yogyakarta berlokasi di Kulon Progo, yaitu New Yogyakarta International Airport (NYIA). Pembangunan bandara baru yang jauh melebihi target waktu yang ditentukan mengindikasikan adanya problematika sosial khususnya resistensi warga dan isu keberlanjutan aktivitas ekonomi dari warga setempat akibat aglomerasi ekonomi dan privatisasi di area yang terdampak pembangunan kawasan kota bandara. Kritik terhadap pembangunan bandara ini muncul karena adanya privatisasi oleh investor asing dalam pembangunan kawasan bandara atau airport city dianggap mengancam keberlangsungan aktivitas ekonomi kelompok rentan. Kajian ini bertujuan untuk menganalisis mekanisme yang dapat mengakomodasi kepentingan kelompok rentan sehingga dapat berpartisipasi dalam pembangunan di kawasan bandara. Kajian ini menghasilkan tiga rekomendasi, yaitu: keperluan adanya grand design pembangunan bandara yang mempertimbangkan keberlanjutan kelompok rentan, inisiasi program community development guna memberdayakan kelompok rentan, dan perlunya perumusan kebijakan afirmatif bagi kelompok rentan dengan mendasarkan pada asas keadilan sosial.
Entre instituciones, espacios y redes: ámbitos interdisciplinarios y transdisciplinarios en América
Authors: Vienni Baptista Bianca
Published: May 2017

¿Por qué pensar en instituciones?
Los factores institucionales son los que se mencionan usualmente como los culpables de impedir las iniciativas interdisciplinarias. Este número de INTERdisciplina presenta una propuesta diferente, desde la cual las instituciones son repensadas como construcciones sociales (Ostrom 1990, 1995) que han aportado y aportan al desarrollo de la interdisciplina en diferentes contextos académicos. En este marco las universidades se erigen como ámbitos privilegiados al constituir espacios donde existe la libertad para generar innovaciones conceptuales y organizacionales que abran la puerta a nuevos modos de producir conocimiento (Weingart 2014).
Las normas mexicanas de catalogación de acervos videográficos y documentos fonográficos, ¿visión a corto o largo plazo?
Authors: Rodríguez García Ariel Alejandro , González Castillo Raúl Ariel
Published: May 2017

En este trabajo se hace un estudio comparativo entre las normas mexicanas de catalogación de acervos videográficos y de documentos fonográficos y las Reglas de Catalogación Angloamericanas, segunda edición, en particular los capítulos seis (videograbaciones) y siete (grabaciones sonoras). Lo anterior con el fin de observar si las normas mexicanas proporcionan consistencia en la presentación de los datos bibliográficos y la asignación del punto de acceso, asuntos que son considerados como los criterios más importantes en el control de calidad de la catalogación. Un argumento importante del estudio es que tanto las instrucciones como la estructura de ambas normas mexicanas están muy lejos de ser consideradas como referentes en el proceso de catalogación en las instituciones nacionales. Además hace falta consenso en el país para que las normas mexicanas sean tomadas en cuenta, puesto que su uso y aplicación está en riesgo de apartarse de una tradición reconocida y compartida.
Research-based knowledge to corporate businesses: the Danish experience
Authors: Mejlbjerg Anders
Published: May 2017

One of the goals in the Danish Government’s strategy for growth in Denmark is to promote the awareness, access and use of research-based knowledge to citizens and institutions, both private and public. In gaining better use of research-based knowledge, Denmark’s chances of being able to play a prominent role as a knowledge society, both nationally and internationally, will substantially increase. To transform the strategy into practice Denmark’s Electronic Research Library, deff, has been created. In this article business consultant of deff, Anders Mejlbjerg, describes how deff is working to expand the awareness of research-based knowledge to various public institutions and to small and medium-sized private enterprises, known  as SMEs.
Minería de texto: una visión actual
Authors: Contreras Barrera Marcial
Published: May 2017

En la actualidad, debido a las actividades sociales, económicas y académicas, en conjunto con la utilización de las Tecnologías de Información y Comunicación (TIC), la producción de conocimiento y de información digital se genera cada vez con mayor rapidez y, en ocasiones, se acumula en enormes volúmenes de información en espera de un procesamiento adecuado. Áreas como la minería de datos y la minería de texto son utilizadas en el procesamiento automatizado de información, las cuales ofrecen la posibilidad de explorar grandes cantidades de datos o texto, estructurados y no estructurados, para buscar patrones, encontrar relaciones y extraer conocimiento; por lo que el propósito del presente artículo es mostrar las características y aplicación de la minería de texto como área emergente en el procesamiento de información digital.
Alfonso Reyes y su legado al mundo del libro: una faceta recuperada
Authors: Galarza Barrios Pilar , Cervantes Méndez Carlos , González Eric
Published: May 2017

El estudio explora una vertiente de la obra multifacética de uno de los humanistas mexicanos más reconocidos en el mundo: Alfonso Reyes. Poeta, ensayista, narrador, dramaturgo y diplomático, es uno de los pensadores más importantes del siglo xx y referente de la cultura mexicana. Se ha escrito mucho acerca de su legado, su estilo, géneros y temas abordados, sin embargo, este trabajo recupera la labor y relación que Don Alfonso Reyes tuvo como un conocedor del libro, su historia y las bibliotecas, se divide en tres apartados: el primero describe su vida y obra; el segundo, dedicado a la asociación llamada El Ateneo de la Juventud y sus maestros y el último a una sección de su obra titulada Libros y libreros de la antigüedad, en donde las aportaciones de Reyes al terreno de la bibliotecología merecen ser conocidas, revisadas y revaloradas.
Estudio de los fondos de origen de la Biblioteca Palafoxiana en Puebla
Authors: Roque Quintero José
Published: May 2017

Se presentan los resultados de una investigación, de la colección de la Biblioteca Palafoxiana en la ciudad de Puebla, que abarca del siglo xv al xx inclusive, realizada de 2013 a 2015. Muestra los resultados del análisis cuantitativo y cualitativo de la colección completa de la Biblioteca. Se aplicó la técnica estadística que incluye un análisis cualitativo y cuantitativo de los datos para el análisis de la colección. Los resultados nos muestran los datos y las estadísticas comparativas por año de publicación, la frecuencia de publicación, el análisis de género de los autores, el comparativo entre títulos y volúmenes, los lugares de publicación y edición, las temáticas de mayor incidencia, los lenguajes preponderantes de publicación, las características bibliográficas especiales, los editores e impresores más destacados, así como las marcas de fuego y ex libris de propiedad. Lo cual permite tener una idea muy completa acerca de los fondos que dieron origen a la actual biblioteca.
Human capital expenditures and company sales turnover
Authors: Makgata Reginah N. , Ngwakwe Collins C.
Published: May 2017

Employee skills development, Health and Safety are key human capital expenditures to enhance company productivity and profitability. Therefore, this research evaluated the relationship between human capital expenditures and company turnover. The study was deemed necessary to evaluate how employee’s productivity can be improved in the existing companies through human capital investment, which will result in good performance towards the firm’s profitability. The research inclined on two major objectives – to analyse the relationship between employees’ health and safety investment and turnover, and to evaluate the relationship between employees’ skill development investment and turnover. Applying a quantitative approach, the correlation statistics was used to analyse the secondary data collected over a period of 5 years (2011–2015) from the archives of selected companies in the JSE SRI. Findings from statistical analysis revealed that for objectives 1, P-value was 0.05, which signifies a relationship between health and safety investment and turnover. This also implies that the lesser the Lost time Injury frequency rate due to health and safety the higher the company turnover. For objective 2, the P-value was less than 0.05, which implies that the more companies invest on skills development of their workforce the higher the turnover. Based on these findings, the paper recommends that companies may expedite strategic investment in employees’ health and safety and skills development to enhance growth in corporate sales turnover.
Nanotechnology and accounting issues
Authors: Rababah Abedalqader
Published: May 2017

Nanotechnology is a new advanced technology used in the industry. This study conducted an investigation on the literature and highlighted the accounting issues which related to the implement of nanotechnology, especially the change of cost structure and expected solutions for the increasing of indirect costs which need more accurate allocation to the unit of products. Also, this study investigated on the future expected accounting risks for using nanotechnology. Finally, this study will open the door for further studies about nanotechnology and different accounting issues in the future