bluuebunny/crossref_metadata_2025 huggingface dataset:
Dual Mobility Acetabular Cup Versus Hemiarthroplasty in Treatment of Displaced Femoral Neck Fractures in Elderly Patients: Comparative Study and Results at Minimum 3-Year Follow-up
Authors: Ukaj Skender , Zhuri Osman , Ukaj Fatime , Podvorica Vlora , Grezda Kushtrim , Caton Jacques , Prudhon Jean Louis , Krasniqi Shaip
Published: May 2019

Background:

Hip fractures are serious injuries associated with relatively high mortality rates and disabilities, commonly seen in elderly persons. There is an ongoing debate regarding the advantages of various hip arthroplasty devices. This study aimed to analyze the long-term advantages of 2 different surgical procedures and assess if the dislocation rate, Harris Hip Score (HHS), and functional independence measure (FIM) are more favorable in dual mobility (DM) than those in hemiarthroplasty (HA).

Hypothesis:

Dual mobility procedures provide better postoperative outcomes than HA in terms of HHS, FIM, and dislocation rate.

Materials and Methods:

The survey was a prospective, comparative interventional single-blinded study performed at the University Clinical Center of Kosovo, a tertiary health-care institution. A total of 94 patients underwent DM or conventional bipolar HA for repair of displaced femoral neck fractures within 2 weeks of injury. Primary outcomes were postoperative dislocation rate, FIM, and HHS. Secondary outcomes included duration of surgery, estimated intraoperative blood loss, time to first postoperative full weight-bearing, time to walking ability with and without crutches, mortality rate, and postoperative infection rate.

Results:

There were no significant differences for most parameters between the groups. We found a significant difference in the dislocation rate between the 2 groups, wherein there were no dislocations in the DM group and 3 dislocations in the HHS group (0% vs 6.4%). In terms of postoperative HHS at 12 months and 3 years, DM provided better outcomes (<0.034 and <0.014, respectively).

Discussion:

Dual mobility compares favorably to HA in terms of dislocation rate and HHS, while no difference was found for FIM. In order to have a more complete overview, we recommend more intense long-term studies including several heterogeneous parameters to compare the clinical outcomes between DM and HA.

Level of evidence (with study design):

Level II.
Measuring the Ecological Impact of the Wealthy: Excessive Consumption, Ecological Disorganization, Green Crime, and Justice
Authors: Lynch Michael J. , Long Michael A. , Stretesky Paul B. , Barrett Kimberly L.
Published: May 2019

Ecological disorganization stemming from conspicuous consumption practices is understudied in the social sciences. In this analysis, we study conspicuous consumption and its implications for environmental sociology, ecological footprint analysis, and green criminology. We examine the issue of conspicuous consumption through the study of items that increase the ecological footprint considerably, that is, through the consumption of “luxury commodities.” Specifically, we draw attention to assessing aspects of ecological footprints of super yachts, super homes, luxury vehicles, and private jets. Taken together, the construction and use of these items in the United States alone is likely to create a CO2 footprint that exceeds those from entire nations. These results are not necessarily surprising but suggest that excessive consumption practices of the wealthy may need to be reinterpreted as criminal when they disrupt the normal regeneration and reproduction of ecosystems by generating excessive ecological disorganization.
If You Offer It, Will They Come? Patterns of Application and Enrollment Behavior in a Universal Prekindergarten Context
Authors: Shapiro Anna , Martin Eleanor , Weiland Christina , Unterman Rebecca
Published: May 2019

Universal public prekindergarten programs have been expanding in recent years, but not all eligible families apply to these programs, for reasons that are not well understood. Using two cohorts of students ( N = 8,391) enrolled in Boston Public Schools, we use geographic information systems to combine administrative records with census data to compare the student-, neighborhood-, and school-level characteristics of kindergarteners who did and did not apply to the Boston Public Schools prekindergarten program. We find that nonappliers are more likely to be non-White ( SD = 0.27), low income ( SD = 0.11), and dual language ( SD = 0.58), particularly those who did not attend any other prekindergarten program. We find similar differences at the neighborhood and school levels. Our study provides some of the first descriptive information on the sociodemographic characteristics and spatial distribution of families who opt out of applying to universal prekindergarten programs. Findings may inform recruitment strategies to promote equitable and universal prekindergarten enrollment.
Fluorescent Tools to Analyze Peroxisome–Endoplasmic Reticulum Interactions in Mammalian Cells
Authors: Bishop Alexa , Kamoshita Maki , Passmore Josiah B. , Hacker Christian , Schrader Tina A. , Waterham Hans R. , Costello Joseph L. , Schrader Michael
Published: May 2019

Peroxisomes (POs) and the endoplasmic reticulum (ER) cooperate extensively in lipid-related metabolic pathways, and the ER also provides phospholipids to enable the peroxisomal membrane to expand prior to division. Recently, we identified peroxisomal proteins, ACBD5 and ACBD4, and the ER protein vesicle-associated membrane protein-associated protein-B (VAPB) as tethering components, which physically interact to foster PO–ER associations at membrane contact sites. Overexpression or loss of these tether proteins alters the extent of PO–ER interactions, impacting on lipid exchange between these two compartments. To facilitate further studies into PO–ER associations at the level of membrane contact sites, their role, composition, and regulation, we have developed two fluorescence-based systems to monitor PO–ER interactions. We modified a proximity ligation assay and a split-fluorescence reporter system using split superfolder green fluorescent protein. Using the proximity ligation assay, we were able to measure the changes in PO–ER interactions while the split-fluorescence reporter was more limited and only allowed us to label PO–ER contacts. We show that both techniques can be useful additions to the toolkit of methods to study PO–ER associations and explore the relative merits of each.
French translation, cultural adaptation and validation of the BDDQ-AS for rhinoplasty patients
Authors: Milad Daniel , Atallah Marie-Renée , Benamer Youcef-Hamza , Saltychev Mikhail , Most Sam P. , Moubayed Sami P.
Published: May 2019

The Body Dysmorphic Disorder Questionnaire-Aesthetic Surgery (BDDQ-AS) is a validated questionnaire that is used as a screening tool for body dysmorphic disorder (BDD) in aesthetic rhinoplasty patients. The BDDQ-AS questionnaire was translated from English to French according to international guidelines. Ten French-speaking rhinoplasty patients were interviewed in order to evaluate the understandability and acceptability of the translation and produce a final version. It was then administered to 165 consecutive patients. Psychometric properties were evaluated using item-reponse theory (IRT). Internal consistency was high, with Cronbach's alpha of 0.90 (95% lower CL 0.88). While the discrimination abilities of all the items were good (over 2.0), their difficulty parameters were shifted towards greater severity of symptoms. That shift could also be observed in information function graph for the entire scale. In other words, the BDDQ-AS performed better in patients with more severe body dysmorphic symptoms. In conclusion, the BDDQ-AS was translated, adapted, and psychometrically validated for use in a French-speaking population.
Polynomial-based density inversion of gravity anomalies for concealed iron-deposit exploration in North China
Authors: Liu Jie , Zhang Jianzhong , Jiang Li , Lin Qi , Wan Li
Published: May 2019

Inversion of residual gravity anomalies is an important geophysical technique for depicting subsurface density contrasts, for example, for mineral deposits. We have expressed subsurface density variations using depth-variable polynomial functions and developed the polynomial coefficient inversion (PCI) method, which is an alternative method for mapping subsurface density distributions by inverting the coefficients of density-contrast functions. PCI enables the linear inversion of density variations without vertically subdividing the subsurface. Synthetic tests indicate that PCI combines polynomial functions and multiple constraints to highlight the anomalous masses through an iterative process with appropriate weighting parameters. We apply our method to a local investigation of banded iron formation (BIF) deposits in the Hebei Province, North China. The inversion results depict the approximate distribution of the subsurface density contrasts to identify the stratigraphic boundaries of different lithologies and BIF-favorable zones, thus implying that local iron-rich ore bodies may be located at the syncline axis or dip along the faults. The successful application of PCI for the BIF deposits indicates that this method is a promising strategy for density mapping.
A machine-learning benchmark for facies classification
Authors: Alaudah Yazeed , Michałowicz Patrycja , Alfarraj Motaz , AlRegib Ghassan
Published: May 2019

The recent interest in using deep learning for seismic interpretation tasks, such as facies classification, has been facing a significant obstacle, namely, the absence of large publicly available annotated data sets for training and testing models. As a result, researchers have often resorted to annotating their own training and testing data. However, different researchers may annotate different classes or use different train and test splits. In addition, it is common for papers that apply machine learning for facies classification to not contain quantitative results, and rather rely solely on visual inspection of the results. All of these practices have led to subjective results and have greatly hindered our ability to compare different machine-learning models against each other and understand the advantages and disadvantages of each approach. To address these issues, we open source a fully annotated 3D geologic model of the Netherlands F3 block. This model is based on study of the 3D seismic data in addition to 26 well logs, and it is grounded on the careful study of the geology of the region. Furthermore, we have developed two baseline models for facies classification based on a deconvolution network architecture and make their codes publicly available. Finally, we have developed a scheme for evaluating different models on this data set, and we have evaluated the results of our baseline models. In addition to making the data set and the code publicly available, our work helps advance research in this area by creating an objective benchmark for comparing the results of different machine-learning approaches for facies classification.
Οι πεποιθήσεις των παιδιών για τη μετά θάνατον ζωή: Επισκόπηση της σύγχρονης έρευνας
Authors: Kornilaki Ekaterina N. , Misailidi Plousia
Published: May 2019

This paper reviews recent studies investigating children's afterlife beliefs. In doing so, the paper concentrates on the following questions: (a) At what age do children begin to believe in the afterlife and what is the developmental course of their beliefs? (b) Is children's belief in the afterlife grounded on a common-sense dualism; is this belief related to constraints of the human cognitive system; or is it the consequence of religious indoctrination and other socio-cultural influences? Finally, the paper attempts a critical discussion of the research findings, and discusses the prospects for future research.
Pentraxin 3 regulates neutrophil infiltration to the brain during neuroinflammation
Authors: Rajkovic Ivana , Wong Raymond , Lemarchand Eloise , Tinker Rory , Allan Stuart M. , Pinteaux Emmanuel
Published: May 2019

Introduction: The acute phase protein pentraxin 3 (PTX3) is known for its anti-inflammatory effects through downregulating neutrophil transmigration during peripheral inflammation. Furthermore, we have previously demonstrated a neuroprotective and neuroreparative effect of PTX3 after cerebral ischaemia. Here we investigated, to our knowledge for the first time, the role of PTX3 in neutrophil transmigration and neurotoxicity following lipopolysaccharide (LPS)-induced cerebral inflammation and cerebral ischaemia.

Methods: Neutrophil transmigration through interleukin-1β (IL-1β) activated brain endothelium and neurotoxicity of neutrophils isolated from wild-type (WT) or PTX3 knock-out (KO) mice was assessed in vitro. Primary cortical neuronal death after treatment with transmigrated neutrophils was quantified by lactate dehydrogenase (LDH) assay. Cerebral inflammation or ischemia was induced in WT and PTX3 KO mice via intrastriatal LPS injection or by transient middle cerebral artery occlusion (MCAo) respectively. Subsequent neutrophil infiltration in the brain was assessed by immunohistochemistry and the expression of pro-inflammatory cytokines interleukin-6 (IL-6) and IL-1β by enzyme-linked immunosorbent assay (ELISA).

Results: Neutrophils isolated from WT mice after intrastriatal LPS injection transmigrated significantly more through IL-1β activated brain endothelium compared to neutrophils from PTX3 KO mice. Transmigrated WT and PTX3 KO neutrophils were significantly more neurotoxic than corresponding non-transmigrated neutrophils; however, no significant differences in neurotoxicity between genotypes were observed. PTX3 reduced the number of transmigrated neutrophils to the brain after intrastriatal LPS injection. Furthermore, PTX3 KO mice showed significantly increased levels of neutrophils in the brain after LPS administration or in the ischaemic hemisphere after MCAo, compared to WT mice.

Conclusion: Our study shows that PTX3 regulates neutrophil transmigration in the CNS during neuroinflammation, demonstrating the potential of PTX3 as an effective therapeutic target in neuroinflammatory conditions.
The association between health literacy and pesticide use behaviors among sweet corn farmers in the Pak Chong district of Thailand: a cross-sectional study
Authors: Pobhirun Theerachai , Pinitsoontorn Somdej
Published: May 2019

Background: Pesticide toxicity is an important health problem in Thailand due to the intensive use of hazardous pesticides.  This study aimed to determine and discuss patterns of pesticide use, health literacy, pesticide use behaviors and whether there is an association between health literacy and pesticide use behaviors among sweet corn farmers in the Pak Chong district, Thailand.

Methods: This work was carried out between May 2017-July 2017 and 161 participants were enrolled. Participant questionnaires were completed during face-to-face interviews.

Results:  This study found the response rate was 98.98%. 161 farmers were interviewed about patterns of chemical pesticide use. Two of the pesticides used in the pre-planting phase were moderately toxic: paraquat (used by 55.2% of farmers) and imidacloprid (used by 15.5% of farmers). In the pre-emergence phase, participants reported using two moderately toxic pesticides: alachlor (used by 48.8% of farmers) and chlorpyrifos (used by 2.4% of farmers). At the post-emergence phase, participants reported using six moderately toxic pesticides: chlorpyrifos (used by 60.7% of farmers), paraquat (used by 38.1% of farmers), imidacloprid (used by 7.2% of farmers), 2-4D (used by 3.6% of farmers), abamectin (used by 3.6% of farmers) and cypermethrin (used by 1.2% of farmers). Health literacy levels were moderate level (Mean score = 91.62, SD = ± 7.06) and pesticide use behaviors were low level (Mean score = 67.80, SD = ± 4.04). When examining the association between health literacy and pesticide use behaviors, we found that functional literacy was significantly associated with pesticide use behaviors. This suggests that health literacy, which includes self-management and decision-making skills, should be given greater attention as pesticide use behaviors were unsafe.

Conclusion: It may be necessary to develop approaches to reduce pesticide use and promote health literacy, thereby protecting farmers, consumers, the environment (soil, water, and air) and ecosystems from pesticide-related hazards.
Case Report: Concomitant coronary stent and femoral artery thrombosis in the setting of heparin-induced thrombocytopenia
Authors: Ben Messaoud Mejdi , Maatouk Mezri , Boussaada Mohamed Mehdi , Mahjoub Marouane , Mnari Walid , Gamra Habib
Published: May 2019

Heparin induced thrombocytopenia (HIT) is a rare but potentially life threatening  adverse drug reaction. We report an unusual case of concomitant subacute coronary stent and femoral artery thrombosis secondary to HIT. In the current era of extensive growth of heparin use and percutaneous coronary interventions, it’s important for clinicians to remember that such complication might occur and should be prevented.
The yield of continuous EEG monitoring in the intensive care unit at a tertiary care hospital in Saudi Arabia: A retrospective study
Authors: Tayeb Haythum O.
Published: May 2019

Background: The practice of continuous EEG monitoring (CEEG) in the intensive care unit (ICU) has been spreading over the past decade. Building an effective ICU CEEG program with sufficient quality demands adequate EEG equipment and significant human resources. While this is available in large tertiary care centers where the practice of CEEG has developed, it may not be available in developing healthcare systems. This study sought to provide data generated from a CEEG program in the adult ICU at a tertiary healthcare center in Saudi Arabia, shedding light on the real-life utility of CEEG in a developing healthcare system.

Methods: This is a retrospective review of CEEG findings, along with mortality and duration of hospitalization of patients who had CEEG during a 12-month period at the adult ICU at the King Abdulaziz University Hospital (KAUH) in Jeddah, Saudi Arabia.

Results: A total of 202 CEEG records were identified. A total of 52 patients had non-convulsive seizures (NCS); 10 clearly fulfilled criteria for non-convulsive status epilepticus. There were 120 patients that had clinical seizures upon presentation. Among them, 36 (30%) had NCS on EEG. The proportion of patients who were deceased at 60 days was higher in patients who had NCS (42%) than those who didn’t (26%, χ2  (2, n=200)= 4.4, p=0.03). The duration of hospital stay was longer for those who had periodic or rhythmic CEEG patterns (χ2 (2, n=200)= 7.6, p=0.02) but there was no significant relationship with mortality at 60 days.

Conclusion: This study demonstrates a real-world experience from a tertiary care center in Saudi Arabia, a developing healthcare system. Findings are consistent with prior experience with ICU CEEG, demonstrating that finding ictal, rhythmic or periodic patterns is associated with morbidity and mortality. Further studies are needed to demonstrate how the practice of CEEG may alter patient outcomes.
Udział kupców ormiańskich w handlu winem w Piotrkowie w XVII i XVIII wieku
Authors: Majewski Marcin Łukasz
Published: May 2019

Armenian Tradesmen’s Share in Wine Trade in Piotrków in the 17th and 18th CenturiesIn the 17th and 18th the patriciate in P iotrków amassed fortune due to profits from wine trade activity. The profits also were going to A rmenian pockets, as A rmenian tradesmen were settling in town. The preserved sources, however scarce, help trace A rmenian commercial activity and define its status on the local wine market. A t that time the following A rmenian families dealt in wine: the A ugustynowicz, the A ntoniewicz, the Derjakubowicz, the Balsamowicz, and the M uradowicz. A s Greek commercial competitors grew stronger, A rmenians gradually moved to other urban centres. Both Greek and I talian tradesmen soon came to replace them in P iotrków. They used to dominate that market in the 16th century.
Wyniki badań składu chemicznego próbek tkanin z haftowanego velum ze zbiorów Muzeum Uniwersytetu Jagiellońskiego Collegium Maius, nr inwentarza 3846/IV
Authors: Biborski Mateusz R.
Published: May 2019

Test Results on the Chemical Composition of the Embroidered Veil of the Jagiellonian University Collegium Maius Museum, inv. no. 3846/IVThe article presents test results on the chemical composition of the metal braid around silk thread and sheets used in the embroidery of the Armenian chalice veil stored in the Jagiellonian University Museum. The results show that metal elements were made of high-quality silver sheet.
Kulisy nominacji następcy ormiańskokatolickiego arcybiskupa Lwowa Józefa Teodorowicza
Authors: Krzyżowski Tomasz
Published: May 2019

Behind the Scenes of the Appointment of the Successor of the Armenian Catholic Archbishop of Lwów, Józef TeodorowiczAlready in 1935 the archbishop of Armenian Catholics in Poland, Józef Teodorowicz, turned himself to the the C ongregation for the Oriental Churches to ask for appointing a coadjutor with the right of succession. He pointed to Rev. Andrzej Łukasiewicz from Czerniowce and Rev. Adam Bogdanowicz from Lwów as potential candidates for the post. Neither of them was eventually appointed, because the Holy See was considering closing the archdiocese and also questioned candidates’ qualifications. After the archbishop’s death (4 December 1938), the issue was re-raised, however, the candidates chosen by the archdiocese were rejected by the C ongregation for the Oriental Churches and Apostolic Nunciature in Warsaw. The rejected candidates were: Rev. Dionizy Kajetanowicz, Rev. Walerian Bąkowski, and Rev. Kajetan Amirowicz. Thus Łukasiewicz’s candidature was re-considered. The article presents opinions about Łukasiewicz and the situation of the Armenian Archdiocese in Lwów. Eventually, Łukasiewicz’s nomination turned out void both due to extended debates in Vatican dicasteries and the outbreak of World War II.
Najnowsza edycja źródłowa profesora Edwarda Tryjarskiego
Authors: Pisowicz Andrzej
Published: May 2019

The Latest Source Edition by Prof. Edward TryjarskiThe author highly values the latest source edition contributive to history of Armenians from Lwów by prof. Edward Tryjarski (Zapisy sądu duchownego Ormian miasta Lwowa za lata 1564-1608 w języku ormiańsko-kipczackim (Records from the Spiritual Court of Lwów’s Armenian between 1564-1608 in Armenian-Kipchak language), Kraków 2017, v. 1 of the series Pomniki dziejowe Ormian polskich [Historical Memorials of Polish Armenians], s. 791, CD). It documents the activity of the institution vital both to the Armenian self-government and Polish judicial system. The reviewer includes a few transcriptions of texts in Kipchak-Armenian ethnolect used by Armenians from Lwów drawn up by himself.
Odnaleziona księga gminy ormiańskiej w Zamościu
Authors: Stopka Krzysztof
Published: May 2019

A Newly Found Book of Armenian Community in ZamośćThe Armenian community in Zamość developed in the 80s of the 16th century. In 1589 Jan Zamoyski, a hetman and chancellor of The Kingdom of Poland, as well as the city owner, allowed for creating an independent Armenian court with its vogt and jurors. The court proceeded by Magdeburg law, which was in force in Zamość, and by Armenian law which had been approved by King Sigismund I in 1519. The Armenian court acts record plaints, defences, testimonies, sentences, notary acts, election protocols of the Armenian selfgovernment, tax rolls, city owners edicts, copies of sentences which concerned Armenians from other courts. Until very recently there has been only seven books of this kind, all stored in the National Archive in Lublin. Last year another book kept between 23 October 1660 and 23 September 1668 was found in the National Historical Archive in Minsk in Belarus.
Physical education in Primary Health Care: reports on interactive actions in an undergraduate course
Authors: Silva Danilo Fernandes da , Coutinho Silvano da Silva , Piccinini-Vallis Helena , Queiroga Marcos Roberto
Published: May 2019

The objective this study was to describe experiences that reflect interactive actions in the program content of the Physical Education and Primary Health Care (PHC) course in the undergraduate (bachelor) degree in Physical Education at the Midwestern Parana State University (UNICENTRO). Activities that aimed to promote students’ understanding of the area and of their role in the health care team through interactions with other professors and professionals from the multidisciplinary residency with emphasis in family health for professionals of Physical Education, Nutrition, Nursing and Physical Therapy are described. The highlighted activities include a review of the legislation supporting the inclusion of the Physical Education professional in the PHC as well as documentaries based on previous reports from a professor in the area. Moreover, studies regarding the skills of the Physical Education professional in Primary Health Care, a comparison between the reality of Primary Health Care in Canada and the PHC, and the interventions developed by the multidisciplinary residents representing Physical Education. We hope this experience report facilitates continuous discussion about the teaching-learning process in the field of Physical Education and public/collective health, mainly in the field of Primary Health Care.
Tissue Morphology and Antigenicity in Mouse and Rat Tibia: Comparing 12 Different Decalcification Conditions
Authors: Bogoevski Kristofor , Woloszyk Anna , Blackwood Keith , Woodruff Maria A. , Glatt Vaida
Published: May 2019

Conventional bone decalcification is a time-consuming process and is therefore unsuitable for clinical applications and time-limited research projects. Consequently, we compared the effect of four different decalcification solutions applied at three different temperatures, and assessed the rate of decalcification and the implications on tissue morphology and antigenicity of mouse and rat tibiae. Bones were decalcified with 10% ethylenediaminetetraacetic acid (EDTA), 10% formic acid, 5% hydrochloric acid, and 5% nitric acid at 4C, 25C, and 37C. Decalcification in both species was fastest in nitric acid at 37C and slowest in EDTA at 4C. Histological and immunohistochemical staining confirmed that the conventional protocols of EDTA at 4C and 25C remain the best option regarding the quality of tissue preservation. Whereas formic acid at 4C is a good alternative saving about 90% of the decalcification time, hydrochloric and nitric acids should be avoided particularly in case of rat tibia. By contrast, due to their smaller size, mouse tibiae had shorter decalcification times and tolerated higher temperatures and exposure to acids much better. In conclusion, this study demonstrated that depending on the specific research question and sample size, alternative decalcification methods could be used to decrease the time of decalcification while maintaining histological accuracy.
Por que não recomendar estatinas como prevenção primária?
Authors: Tesser Charles Dalcanle , Norman Armando Henrique
Published: May 2019

Este artigo tece uma crítica à mudança de postura e práticas médicas a respeito do uso de estatinas como prevenção primária (P1). Tal tema é de grande relevância clínica para a atenção primária à saúde e para a saúde pública. No Tratado de Medicina de Família e Comunidade (edição de 2018), o capítulo sobre P1 de doenças cardiovasculares assume implicitamente que as estatinas devem ser usadas como P1, sem discussão dos problemas envolvidos nisso. Este artigo faz uma síntese dos problemas e polêmicas envolvidos na prescrição de estatinas em P1 a partir de 2012, quando uma primeira metanálise recomendou esse uso. Discutimos criticamente as evidências a respeito, a partir de clássicos critérios éticos e técnicos. Defendemos que a evidência para usar estatinas como P1 é muito fraca e não confiável, frente a danos potenciais significativos e benefícios muito pequenos. Mais pesquisas são necessárias, mais transparentes e com menos influência da indústria farmacêutica.
Editorial
Authors: APS em Revista Editoria Científica
Published: May 2019

Editorial
Oferta de cuidado primário para doenças crônicas: uma análise da eficiência técnicas das equipes de saúde brasileiras
Authors: Rocha Thiago Augusto Hernandes , Da Silva Núbia Cristina , Vissoci João Ricardo Nickenig
Published: May 2019

Este trabalho é proposto para realizar uma análise relativa da eficiência dos governos estaduais no que diz respeito aos cuidados de saúde prestados pelas equipes de saúde da família em relação à prevenção do diabetes e da hipertensão, no que diz respeito ao controle e com respeito ao acompanhamento. A avaliação da efetividade foi feita por meio da Análise de Envolvimento de Dados - DEA, e adotando o modelo Scales de Regressões Constantes (CRS) focado nos resultados. Os resultados encontrados evidenciam a necessidade de melhorar a atenção à saúde da população e indicam a necessidade de intervenções nos procedimentos de trabalho em saúde.
Diagnostic Value of C-Reactive Protein in Patients with Angiographically Documented Coronary Heart Disease
Authors: Eren Esin , Yılmaz Necat , Pençe Sadrettin , Koçoğlu Hasan , Göksu Sıtkı , Kocabaş Ramazan , Kadayıfcı Sinan
Published: May 2019

Aim: The aim of this study was to evaluate the diagnostic value of serum C-reactive protein (CRP) level measurement in predicting coronary artery disease (CAD) that can be shown angiographically. Methods: CRP levels were determined in the blood of 198 patients (patients group, PG) with angiographically documented coronary artery disease and compared with that of 85 patients (control group, CG) who had a clinical indication for coronary angiography but have no angiographically determined coronary artery stenosis, as well as with that of 41 healthy volunteers as a healthy control group (HG) who did not have any complaint and did not have coronary angiography. CRP levels were measured 24 hours prior to angiography in PG and CG patients, and in the morning after not having eaten for same time. Any coronary artery stenosis or plaque formation was defined as CAD. Severity of the disease was assessed by both the number of diseased vessels (0 to 3) and the degree of stenosis (<50 % mild, 50–70 % moderate and >70 % severe). Results: Receiver Operating Characteristics (ROC) curves of CRP in angiographically documented CAD group showed a diagnostic value of 0.659 in female patients, followed by 0.542 in male patients, in predicting CAD. CRP levels were found to be significantly different between groups, higher in PG (6.2 ± 0.86 mg/L) than those of CG (3.7 ± 0.92 mg/L) and HG (0.854 ± 0.2 mg/L) (p<0.05). CRP levels were not associated with the number of diseased vessels, neither with the degree of the occlusion (p>0.05). Multiple logistic regression analysis after adjustment for the established coronary risk factors showed CRP as an independent discriminating risk factor for CAD. Conclusion: It is concluded that CRP measurement has a value in predicting the presence of angiographically documented CAD. However, CRP levels were not associated with the degree or severity of CAD.
Some Recruitment Aspects of Population Photoscreening of Amblyogenic Factors at Children Younger One Year
Authors: Dostálek Miroslav , Benešová Jana
Published: May 2019

The aim of the study was to evaluate the keystone role of paediatric general practitioners (PGPs) in our system of photoscreening of amblyogenic factors at children younger one year. The parental involvement on the participation of their children at photoscreening was also analysed. From June 2000 to February 2001 we have performed 780 photoscreening tests of children aged from 3 months to 31 months (mean age 9.7 months). The photoscreening test was voluntary. Parents was invited to visit screening center by PGP’s recommendation and by offering the Invitation/information brochure. The brochure was distributed by 56 paediatric general practitioners during obligatory examinations at 5., 8. resp. 12. month of age from June to November 2000. Based on the questionnaire (return rate 89 %) we documented following data: the number of children of particular age in the care of PGPs was 2060, 1458 Invitation/information brochures was distributed by PGPs. PGPs attended for more children at particular age distributed relatively less number of brochures if compared to PGPs with lower number of relative children. The willingness to the photoscreening programe participance of parents of children belonging to PGPs attended our educational seminary exhibited independence on distance between PGP office and our department in the strong contrast to families belonging with PGPs not participating on educational programme. Our further effort on elevating the percentage of children population participation on screening must be focused on education of PGP with large number of children at particular age and on ensuring the issuing of brochures or other forms of invitation at PGPs’ offices.
Bridging the gap between the near and the far: Displacement and representation
Authors: Nijk Arjan A.
Published: May 2019

This article discusses the use of proximal deictic expressions to designate distal entities, focusing on the use of the present tense to designate past events. Cognitive approaches to this issue assume that such usages presuppose a special conceptual construal, in which the spatio-temporal distance between the ground and the designated event space is bridged in some way. In this paper, I argue that there are two distinct ways in which this may be accomplished. One is through mentally displacing the ground to the distal space, so that the designated events become proximal in relation to this alternative ground. The other involves bringing the distal space into the ground in the form of a representation. I describe the distinctive characteristics of the two scenarios, showing both where they converge and at what point the difference becomes relevant for linguistic analysis.
Ohne Gewähr oder: Die unsichere Zukunft
Authors: Zirfas Jörg
Published: May 2019

Der Artikel geht der Frage nach, welches Unsicherheitspotential die Vorstellungen von Zukunft in der Moderne haben. Dabei werden unterschiedliche Perspektiven bemüht, die von der Philosophie über die Soziologie bis zur Geschichtsforschung reichen und auf Analytiken, Programmatiken und Zeiterfahrungen von Zukunft abheben. Ausgehend von der Neubestimmung der Zukunft als Zeitalter des Offenen und Neuen seit der Aufklärung wird deutlich, dass Zukunftswissen nicht mehr ausreicht, um (zukünftige) Probleme in einer gültigen und belastbaren Form umfassend zu bestimmen; es reicht auch nicht aus, um Wege und Methoden zu benennen, die die kalkulierten Risiken einer Lösung entgegenführen, und es reicht schließlich auch nicht aus, um alle (kontingenten) Nebenwirkungen exakt vorhersehen zu können. Das verdeutlichen die Debatten um die Erkennbarkeit und Unerkennbarkeit sowie die Diskussion um die Offenheit der Zukunft angesichts der Gegenwartsschrumpfung bzw. der Gegenwartserstreckung. Vor diesem Hintergrund avancieren das Nichtwissen und Nichtwissenwollen zu Potenzialen eines kontingenz-, innovations- und risikobewussten Zukunftsbezugs. Schließlich werden Möglichkeiten des Umgangs mit der Unsicherheit der Zukunft in der Moderne anhand von vier Praktiken vorgestellt: Zaudern, Verhindern, Versprechen und Hoffen.
Ein sicheres Leben lohnt sich ja kaum!
Authors: Körner Jürgen
Published: May 2019

Die wesentlichen Schritte kindlicher Entwicklung gelingen in der Bewältigung von ängstigenden Situationen: Mit der Konsolidierung des „Kern-Selbst“ bewältigt das Kind die Angst, den lebensnotwendigen Anderen zu verlieren, mit der Fähigkeit zur Perspektivenübernahme überwindet es die Angst vor der Unberechenbarkeit seiner Mitmenschen und mit der Errichtung seines Gewissens bändigt es die Angst vor seinen eigenen triebhaften und dissozialen Impulsen. So ist es nicht allein die Erfahrung einer liebevollen Zuwendung, die das Kind zu Wachstum und Entwicklung ermutigt; ebenso notwendig ist es, dass es die unvermeidlichen Erlebnisse des Verlustes und der Enttäuschung bewältigt.
Negative Therapeutik
Authors: Rugenstein Kai
Published: May 2019

Der Beitrag führt die Unterscheidung zwischen einer auf Unsicherheitsbeseitigung ausgerichteten Logik des Machens und einer auf Unsicherheitsnutzung zielenden Logik des Lassens ein. Diese Unterscheidung wird auf den Bereich psychologischer Therapeutik angewendet, wobei Sokrates als erster und paradigmatischer Praktiker einer der Logik des Lassens folgenden therapeutischen Methode gedeutet wird. Der therapeutische Raum, so die weitere Argumentation, lässt sich mit Freud als ein negativer verstehen. Neben Freuds „gleichschwebender Aufmerksamkeit“ wird ergänzend auf John Keats’ poetologisches Konzept der „negative capability“ zurückgegriffen. Ein abschließender Teil erörtert Konsequenzen für den therapeutischen Prozess und das therapeutische Selbstverständnis.
Zwischen normal und abweichend
Authors: Schmidt Friederike
Published: May 2019

Die Lebensphase Kindheit scheint konstitutiv mit dem Thema Unsicherheit verknüpft zu sein. Unsicherheiten betreffen einerseits die Kinder selbst, sei es bei ihren ersten Gehversuchen oder dem Erkunden des familiären und später des öffentlichen Raumes. Unsicherheiten sind andererseits auch bei der für sie verantwortlichen älteren Generation auszumachen, u. a. bei den Eltern, um die es im Weiteren gehen wird. Elterliche Unsicherheiten lassen sich etwa in Bezug auf die Form der außerfamilialen Betreuung oder die Ernährung des Kindes feststellen. In Anlehnung an normalitäts- und normalisierungstheoretische wie kindheitssoziologische Arbeiten scheint der Vielzahl elterlicher Unsicherheiten dabei ein diskursiver Horizont zugrunde zu liegen, in dem die Unsicherheiten eingebettet sind und entworfen werden.
Unsicherheit und Vertrauen
Authors: Bormann Inka
Published: May 2019

Der Beitrag befasst sich mit dem Verhältnis von Vertrauen und Unsicherheit im Zusammenhang mit pädagogischen Interaktionen und ihren institutionellen Rahmungen. Zuerst wird Unsicherheit als konstitutives Merkmal pädagogischer Interaktionen dargestellt und anschließend etwas ausführlicher auf Vertrauen in pädagogischen Interaktionen eingegangen (1). Anschließend wird gezeigt, wie sich die Thematisierung von Vertrauen in Konzepten pädagogischen Denkens und Handelns im Wandel der Zeit verschoben hat (2), bevor anschließend die institutionalisierte Beobachtung pädagogischer Leistungen betrachtet wird (3). Abschließend werden Überlegungen zur Einordnung eines Vertrauens in Instrumente zur Beobachtung institutioneller Leistungen im Bildungssystem dargelegt (4).
Unsicherheit, Krise und Routine
Authors: Bosch Aida
Published: May 2019

Der Beitrag untersucht die Rolle der Dinge für die menschliche Identität auf der kollektiven und individuellen Ebene. Ausgehend von der exzentrischen Positionalität des Menschen sind zunächst „Unsicherheit“ und „Krise“ begrifflich näher zu bestimmen und in ihrer Ambivalenz für menschliche Handlung und Kommunikation zu betrachten. Anschließend wird auf die existenzielle und praktische Rolle der Dinge in der menschlichen Lebenswelt eingegangen und geprüft, welcher Art die besonders geeigneten Dinge und Artefakte sind, die kollektive sowie individuelle Identität in Situationen der Krise zu stabilisieren vermögen.
Physicochemical and biological investigation of oxygen plasma modified electrospun polyurethane scaffolds for connective tissue engineering application
Authors: Ghorbani Farnaz , Zamanian Ali
Published: May 2019

In this study, electrospinning was selected to fabricate randomly oriented polyurethane (PU) nanofibers for tissue engineering application, and the surface of scaffolds was exposed to oxygen plasma flow. The morphology structure of the PU scaffolds before and after oxygen plasma treatment was observed using scanning electron microscopy (SEM) micrographs, and the fiber diameter distribution was measured using Image J software. The results demonstrated that oxygen plasma modification reduces the fiber diameter without any other special effects on fiber microstructure. Water drop contact angle and swelling ratio of PU constructs were performed to estimate the water-scaffolds interactions. The results revealed improvement of hydrophilicity by oxygen plasma treatment. Atomic force microscopy test was done to analyze a topological characteristic of the scaffolds, and it was found out that oxygen plasma treatment decreases the roughness of the scaffolds. The biological behavior of the scaffolds was investigated by SEM observation and MTT assay after L-929 fibroblast cells culture. In vitro assays demonstrated biocompatibility, cellular attachments, and filopodia formation on plasma modified samples. These results suggest that oxygen plasma treatment improves the physicochemical and biological properties of PU scaffolds to create a more hydrophilic surface which facilitates cell attachments and proliferation.
Targetsalden sind nicht empörend, sondern gefährlich
Authors: Homburg Stefan
Published: May 2019

Kürzlich hat Martin Hellwig in den Perspektiven der Wirtschaftspolitik seine Position zu den Targetsalden des Europäischen Währungssystems dargelegt. Stefan Homburg kritisiert nun in diesem Kommentar Hellwigs Ansichten in mehreren Punkten.
Gulf of Alaska Cyclone in Daytime
Microphysics RGB Imagery
Authors: Lawson Michael T. , Fuell Kevin K.
Published: May 2019

The NASA Short-term Prediction Research and Transition (SPoRT) Center has provided National Weather Service (NWS) Alaska Region forecasters with the experimental Daytime Microphysics (DtMicro) red-green-blue (RGB) product to support forecasting aviation hazards (Berndt et al. 2017), which has become an integral tool in the forecast process. On 11 March 2018, a rapidly deepening cyclone entered the Gulf of Alaska and developed gale-force winds and relatively strong convection for late winter, while lowlevel clouds and fog remained in its wake. The multispectral DtMicro RGB (Rosenfeld and Lensky 1998; EUMETSAT User Service Division 2009) provided an efficient product to analyze cloud properties and surface features with improved efficiency compared to single-channel visible or infrared imagery. The DtMicro RGB and 0.64 µm visible images (Fig. 1) show a mature, occluded cyclone over the Gulf of Alaska at 2030 UTC (1230 LST). The DtMicro RGB combines visible and infrared channels related to cloud brightness, particle size, and temperature in order to analyze convective clouds and other cloud and surface features (Table 1; Lensky and Rosenfeld 2008). A limb correction and intercalibration was applied to infrared channels using the technique outlined in Elmer et al. (2016). These adjustments allow for greater consistency across the imager swath and consistency between numerous polar-orbiting satellites. The RGB clearly delineates the back-bent occlusion (dark orange to red), and dry air wrapping into the system, allowing a view of the low to mid-level clouds in the center of
the image. Bright orange/yellow combinations over the Alaska panhandle and northwestern Canada are mountain-wave cirrus clouds composed of small ice particles. The magenta cloud features within the dry slot are deeper convective cells, and cyan to yellowgreen cloud features are low-level water clouds. Near Illiamna, the tan to dull green coloring indicates very low stratus and fog, which is not distinguishable from snow cover in the visible imagery.
How to run a specialist valve clinic: the history, examination and exercise test
Authors: Chambers John B
Published: May 2019

Echocardiography is the key to the detection and initial assessment of valve disease. The examination helps differentiate severe from moderate disease if this is unclear from the echocardiogram, but is less useful than echocardiography for surveillance. However, the history is extremely important because symptoms are an indication for surgery in all types of valve disease. In aortic stenosis, the mortality rises soon after the onset of exertional breathlessness or chest tightness. Exercise testing is an extension of the history and may reveal symptoms in apparently asymptomatic patients. This article discusses the history, examination and exercise testing in patients either newly referred or under routine follow-up in a specialist valve clinic.
High glucose upregulates osteopontin expression by FoxO1 activation in macrophages
Authors: Zhang Qiongge , Wang Chaoqun , Tang Yehua , Zhu Qiangqiang , Li Yongcheng , Chen Haiyan , Bao Yi , Xue Song , Sun Liangliang , Tang Wei , Chen Xiangfang , Shi Yongquan , Qu Lefeng , Lu Bin , Zheng Jiaoyang
Published: May 2019

Hyperglycemia plays a major role in the development of diabetic macrovascular complications, including atherosclerosis and restenosis, which are responsible for the most of disability and mortality in diabetic patients. Osteopontin (OPN) is an important factor involved in atherogenesis, and hyperglycemia enhances the transcriptional activity of FoxO1 which is closely association with insulin resistance and diabetes. Here, we showed that plasma OPN levels were significantly elevated in type 2 diabetic patients and positively correlated with glycated albumin (GA). The more atherosclerotic lesions were observed in the aorta of diabetic ApoE−/− mice analyzed by Sudan IV staining. High glucose increased both the mRNA and protein expression levels of OPN and inhibited the phosphorylation of FoxO1 in RAW 264.7 cells. Overexpression of WT or constitutively active mutant FoxO1 promoted the expression levels of OPN, while the dominant-negative mutant FoxO1 decreased slightly the expression of OPN. Conversely, knockdown of FoxO1 reduced the expression of OPN. Luciferase reporter assay revealed that high glucose and overexpression of FoxO1 enhanced the activities of the OPN promoter region nt −1918 ~ −713. Furthermore, the interactions between FoxO1 and the OPN promoter were confirmed by electrophoretic mobility shift assay (EMSA) and chromatin immunoprecipitation assay (ChIP). Our results suggest that high glucose upregulates OPN expression via FoxO1 activation, which would play a critical role in the development of diabetic atherogenesis.
Concentration of uranium isotopes by in-situ coprecipitation on activated coal and iron (III) hydroxide
Authors: Matveyeva Ilona , Meiirman Fatima , Nursapina Nurgul , Satybaldiyev Bagdat , Tuzova Tamara , Shalabayev Zhandos , Shynybek Balnur
Published: May 2019

The use of the method of nonequilibrium uranium in various branches of science led to the necessity to determine its isotopic composition. The content of uranium isotopes in natural waters is often extremely low, therefore, it is necessary to collect significant volumes of samples in order to obtain reliable results of analysis. In this paper, it is proposed to concentrate uranium isotopes from water in-situ. Two alternative methods of uranium coprecipitation in field conditions (on activated carbon and iron (III) hydroxide) are considered. The desorbed uranium isotopes are determined by an alpha-spectrometric method with preliminary radiochemical preparation in laboratory conditions, including extraction with tributyl phosphate and electrodeposition on a steel disc. It was found that when concentrating on activated carbon the chemical yield was from 2 to 32%, and when concentrating on iron (III) hydroxide it is from 15 to 62%. For the second case, the chemical yield is acceptable for radiochemical work, and the proposed method for concentrating of uranium isotopes is recommended for usage in field conditions. Approbation of the method was carried out within the framework of the PEER454 project in 2017 in the valley of the river Ziddy, Pamir-Alay, Republic of Tajikistan. Work in the field conditions showed high efficiency of the method and its full feasibility even in the absence of acceptable laboratory conditions.