bluuebunny/crossref_metadata_2025 huggingface dataset:
AS LUTAS COMO CONTEÚDO DA EDUCAÇÃO FÍSICA ESCOLAR
Authors: De Luna Ivan Martins Leite , Moutella Antonio Neto , Feitosa Luis Carlos
Published: September 2023

Resumo: As lutas como conteúdo da Educação Física Escolar possibilitam o trabalho a partir de outros temas e contribuem para a prática pedagógica. O objetivo deste estudo foi investigar a relevância das lutas como conteúdo da Educação Física Escolar. A metodologia utilizada foi a revisão de literatura a partir de autores que relacionam a inserção do conteúdo de lutas nas aulas de Educação Física. Foram também utilizados dois documentos legais referentes a área, determinando os aspectos conceituais, procedimentais e atitudinais. Os resultados demonstraram a significância das atividades desenvolvidas nas lutas para a formação da cultura corporal do movimento.
COVID Graffiti as a Genre of Literary Writing
Authors: Yernzkyan Yelena , Gasparyan Grisha
Published: September 2023

The present paper focuses on COVID graffiti as a unique genre of literature. The application of Multimodal Discourse Analysis research method reveals the narrative potential of COVID graffiti texts. The results of the study point out that COVID graffiti mostly uses intertextuality as a literary discourse strategy to convey an efficient and persuasive message, alongside other strategies meant to express isolated people’s existential fears and concerns, the experienced anxiety and discomfort caused by the “new normal.” The empirical material comes to affirm the inextricable relationship between literature as verbal and the current harsh reality as non-verbal entities that complement each other in the complex process of meaning-making.
Produkthaftung und Digitalisierung
Authors: Denkmaier Christiane
Published: September 2023

Richtlinien der Produkthaftung - für das digitale Zeitalter gerüstet? Diese Monografie beschäftigt sich mit den Auswirkungen neuer Technologien auf die bestehenden Regeln der verschuldensunabhängigen Produkthaftung. Das Buch gliedert sich in drei Bereiche: Zu Beginn folgt ein kurzer historischer Überblick über die Entwicklung der Produzenten- und Produkthaftung ausgehend von der industriellen Revolution im 19. Jahrhundert. Im Anschluss kommt es zu einer näheren Auseinandersetzung mit den Folgen der Digitalisierung für die Produkthaftung. Den Schwerpunkt bilden die Bereiche des Hersteller-, Produkt- und Fehlerbegriffs, sowie die Frage der Beweislast. Untersucht wird unter anderem, ob und unter welchen Umständen Software als Produkt im Sinne der Richtlinie gilt, wer im Rahmen des 3D-Drucks als Hersteller gilt, welche berechtigten Sicherheitsmaßstäbe an smarte Produkte gestellt werden können und wie mit fehlerhaften Updates nach Inverkehrbringen umzugehen ist. Der dritte Teil behandelt etwaige versicherungsrechtliche Konsequenzen. Im Mittelpunkt stehen vor allem die Deckungsvorsorgepflicht des § 16 PHG und die Produkthaftpflichtversicherung.
Importancia del registro y del Derecho de Autor en las obras inéditas
Authors: Sánchez Karla , González Ana , Bayas Romero Edgar Lenin
Published: September 2023

INTRODUCCIÓN. El derecho de autor regula una serie de aspectos que benefician a los autores como son los derechos morales y económicos que otorgan a sus creadores. OBJETIVO. Es así, como este trabajo analiza la importancia del derecho de autor como una forma de garantizar los derechos de aquellas personas que son creadores de diversas obras inéditas que aportan a la sociedad. El Estado ecuatoriano al ser Constitucional de Derechos y Justicia Social, regula los derechos de autor, no sólo desde la parte económica, sino a la vez desde la concepción del Buen Vivir. MÉTODO. Por lo tanto, desde una investigación de revisión bibliográfica, documental se analiza la importancia del derecho de autor, pero sobre todo analiza que las obras deben contar con el debido registro, para contribuir a los derechos que concede la protección de las obras inéditas realizadas por sus legítimos creadores. DISCUSIÓN Y CONCLUSIONES. Se concluye que dicho derecho está enmarcado desde la concepción de los derechos y justicia social, al proteger las prerrogativas morales como patrimoniales.
Treatment Results of Treatment-naïve Neovascular Age-related Macular Degeneration in Patients Over 85 Years of Age
Authors: Kwon Ji Min , Hwang Sung Soo , Bang Jong Wook , Kim Hyun Woong , Lim Jae Wan , Lee Sang Joon , Kim Dong Geun , Kwak Hyun Duck , Pak Kang Yeun
Published: September 2023

Purpose: To investigate the characteristics and treatment results of patients aged ≥ 85 years who were diagnosed with treatment-naïve neovascular age-related macular degeneration (nAMD).Methods: The medical records of patients diagnosed with treatment-naïve nAMD who were ≥ 85 years old at the time of diagnosis with at least 12 months follow-up were retrospectively reviewed. The number of intravitreal injections of anti-vascular endothelial growth factor (VEGF) and agents used during the entire period were investigated. Best-corrected visual acuity and optical coherence tomography results before and after treatment were analyzed. Visual acuity of the fellow eye was also collected.Results: A total of 40 eyes of 40 patients with mean age of 87.5 ± 2.4 were included in the study. The mean logarithm of the minimal angle of resolution visual acuity was 0.85 ± 0.57, and the mean of the fellow eye was 0.93 ± 0.99. Compared to before the treatment, there was no significant difference after intravitreal injection in terms of visual acuity. Central retinal thickness showed significant reduction at all time points after treatment.Conclusions: In patients aged ≥ 85 years at the time of diagnosis, intravitreal injections of anti-VEGF prevented deterioration of visual acuity and showed successful anatomical outcomes. Especially, many had poor visual acuity in the fellow eye, suggesting the importance of maintaining visual acuity. Therefore, active treatment is necessary in the elderly.
Long-term Clinical Outcomes of Patients with Infantile and Refractive Accommodative Esotropia
Authors: Shin Hyemi , Ha Suk Gyu , Suh Young-Woo , Kim Seung-Hyun
Published: September 2023

Purpose: To compare the long-term clinical outcomes of patients with refractive accommodative esotropia (RAET) and infantile esotropia (IET).Methods: The medical records of patients with RAET and IET who were followed-up for more than 36 months were retrospectively analyzed. The RAET patients were prescribed spectacles to correct cycloplegic refraction and those with IET underwent bilateral, medial rectus recession. Visual acuity, refraction, the angle of esodeviation at far and near distances, and near-stereopsis were measured at each visit. The IET patients were divided into two groups by the time of surgery (before and after 24 months of age). Patients in both groups who underwent reoperations after diagnosis of partially accommodative esotropia (PAET) and recurrent IET during follow-up were analyzed.Results: Sixty-nine patients (40 with RAET and 29 with IET) were included. The follow-up period was 69.48 ± 28.41 months. At the final visit, the angles of esodeviation were 2.82 ± 5.46 prism diopters (PD) in the RAET group and 9.28 ± 8.37 PD in the IET group (p < 0.01). In IET patients who underwent surgery before and after 24 months of age, the angles of esodeviation were 4.62 ± 5.25 and 13.06 ± 8.63 PD and the median near-stereopsis values 60 and 140 arcsec at the final visit (p < 0.01, 0.03). Seven patients (17.5%) in the RAET group, and 2 (15.4%) and 10 (62.5%) IET patients who underwent surgery before and after 24 months of age, required reoperations (p < 0.01).Conclusions: RAET and IET patients who underwent surgery before 24 months of age exhibited better alignment and stereopsis at the final visit than those who underwent later surgery and the reoperation rate was lower.
Unilateral Eyelid Swelling Secondary to Local Palpebral Conjunctival Amyloidosis in a Young Patient
Authors: Shin Haeeun , Seo Youjeong , Jung Ji Won
Published: September 2023

Purpose: We report a young patient with unilateral eyelid swelling secondary to local, palpebral conjunctival amyloidosis.Case summary: A 31-year-old male was referred with a 6-month history of mild, right upper eyelid swelling but without redness or tenderness. Slit-lamp examination revealed a diffuse hemorrhagic papilliform lesion on the right upper palpebral conjunctiva, this raised a suspicion of giant papillary conjunctivitis. As the lesion was unilateral, there was no history of allergic disease or contact lens use, and the lesion was refractory to topical anti-inflammatory treatment so, excisional biopsy of the right upper palpebral conjunctiva was performed. During the operation, the papilliform lesion was removed, it peeled off on the blade. After surgery, the eyelid swelling improved. Histopathological examination revealed an eosinophilic amorphous deposit consistent with amyloidosis. Further evaluation ruled out systemic amyloidosis; there were no abnormal findings. Thus, we diagnosed primary localized amyloidosis of the palpebral conjunctiva. At the 1-year follow-up, no recurrence was detected.Conclusions: Although primary localized amyloidosis of the palpebral conjunctiva is rare, this should be considered if chronic eyelid swelling accompanied by another conjunctival lesion such as giant papillary conjunctivitis is encountered.
Food waste matters - The policy implications and sustainability of food waste practices
Authors: Olajuyin Ayobami Matthew , Raji Hayatu , Iwu Adaobi , Okunbor Helen , Albert Karis , Olajuyin Adefunke Kafayat , Bamigbade Adekunle Toyin
Published: September 2023

Food waste has grown in the last couple of years and is recognized by the general public, governments, education, companies, and Non-Governmental Organizations (NGOs) to cause greenhouse emissions and resource reduction. In the food supply chain, food waste is generated at all levels. The purpose of this article is to use information from various scholarly articles to analyze the determinants of consumer food waste and the key elements that facilitate or hinder food waste activities. Furthermore, we briefly discuss the contributions of various theories in understanding food wastage. This analysis shows that food waste needs to be understood and tackled with the views of different disciplines because it is quite complex. Understanding the reasons behind food waste production would aid in the creation of food waste preventive measures and sustainability.
Preditores pré-operatórios de colecistectomia complexa na videolaparoscopia em um serviço de referência do estado do Pará
Authors: Azevedo Valéria Diniz Calandrini de , Pontes Beatriz da Costa , Rodrigues Brenda Caroline , Kalif Lucas da Costa , Rocha Lía Sousa
Published: September 2023

Objetivo: avaliar as características pré-operatórias que predizem uma colecistectomia videolaparoscópica complexa no ato cirúrgico. Metodologia: estudo observacional retrospectivo descritivo através do levantamento de dados em prontuários de pacientes submetidos a colecistectomia na FSCMPA os quais foram analisados através de tabelas expositivas com o uso do programa Microsoft Word® e Microsoft Excel®. Todos os testes estatísticos foram executados com o auxílio do software Bioestat 5.5. Resultados: O sexo feminino na população foi de 114(79,2%) e do masculino, 30(20,8%). A faixa etária mais prevalente foi a de 30 a 59 anos, com 100 atendimentos (69,4%). A média de idade foi de 47,59 anos. A maior frequência da admissão dos pacientes para a realização da cirurgia foi eletiva, constituindo 97,2 % (140) dos casos. A cólica biliar foi o achado clínico mais prevalente e constituiu 74,3 % (107). O segundo mais prevalente foi a presença de colecistite 17,4% (25). Na classificação do risco final a mais prevalente foi o score de 0-a 3, com 75% (108). As chances de apresentarem ducto biliar alterado é 11 vezes maior nos participantes com risco elevado. Conclusão: Os resultados são relevantes para a identificação de possíveis variáveis preditoras pré-operatórias, o que pode contribuir para a melhoria da qualidade do atendimento aos pacientes e do planejamento da gestão em saúde.
Impactos na saúde mental dos profissionais de enfermagem relacionados à atuação em unidades de terapia intensiva para tratamento da COVID-19
Authors: Queiroz Tatiane Aparecida , Carvalho Francisca Patrícia Barreto de
Published: September 2023

Esse estudo tem como objetivo identificar a produção científica acerca dos impactos na saúde mental dos profissionais de enfermagem relacionados à atuação em unidades de terapia intensiva para tratamento da COVID-19. Trata-se de uma revisão integrativa da literatura cuja coleta de dados aconteceu no mês de janeiro de 2023 a partir das bases de dados Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), MEDLINE e Scientific Electronic Library Online (SCIELO). Para a busca dos artigos, utilizou-se os seguintes descritores: “unidades de terapia intensiva AND COVID-19 AND enfermagem AND saúde mental” e “Intensive Care Units AND COVID-19 AND Nursing AND Mental Health”.  Foram selecionados 11 artigos como corpus de análise. Verificou-se que a sobrecarga de trabalho, a escassez de profissionais capacitados para atuação em unidades de cuidados intensivos, a necessidade de constante atualização dos profissionais, o de medo de contaminação própria, de familiares e sociedade, o estigma relacionado à doença, bem como o grande número de óbitos, foram fatores que afetaram diretamente a saúde mental dos profissionais de enfermagem. Identificou-se também uma elevação nos níveis de ansiedade, estresse, depressão e transtorno de estresse pós-traumático durante a atuação dos profissionais de enfermagem nas unidades de cuidados intensivos para COVID-19. Com base nos resultados obtidos, observa-se que é necessária a formulação de políticas que saúde ocupacional, que busquem minimizar a carga mental dos profissionais de enfermagem.
Aplicação de fórmulas infantis em pacientes com galactosemia: Uma revisão integrativa
Authors: Couto Flávia Dantas Santos do , Fonseca Larissa Marrocos de , Gonçalves Ana Carolina Oliveira Santos , Carmo Silva Arthur , Almeida Renata Carvalho , Cedraz Maria Eduarda Santos , Correia Vitória Liz de Souza , Silva Arthur Carmo
Published: September 2023

A galactosemia é conhecida como um erro inato do metabolismo, a qual é incapaz de digerir a galactose, açúcar presente no leite materno, que é a principal fonte de nutrientes para os lactentes. O tratamento realizado nos primeiros meses de vida consiste em suspender a ingestão de leite materno, utilizando as fórmulas infantis. O presente estudo se configura como uma revisão integrativa de literatura. Utilizou materiais científicos publicados de forma online de entidades ligadas à pesquisa científica. Dentre os métodos de revisão, o presente estudo optou pela modalidade integrativa e a estratégia de pesquisa foi definida com o auxílio do PICO (patient, intervention, comparison and outcomes). P: lactentes com galactosemia; I: uso de fórmulas como substituição do leite materno; C: lactentes com galactosemia que passaram a usar fórmulas à base de soja; O: efeito das fórmulas nos sintomas e complicações da galactosemia. A coleta de dados foi realizada entre fevereiro e maio de 2023 e foi norteada pela seguinte pergunta: “Qual a melhor opção de fórmula infantil para lactentes com galactosemia, bem como seus efeitos na melhora dos sintomas?”. O objetivo do artigo constituiu em analisar as indicações do uso de fórmulas infantis como substituição do aleitamento materno em bebês com diagnóstico de galactosemia, bem como seus tipos e benefícios ao tratamento. O trabalho não conseguiu demonstrar melhor efetividade dentre as opções de fórmulas disponíveis e ressaltou a necessidade de novos estudos acerca do objeto de estudo.
Aspectos legais para regularização da agroindústria familiar no Brasil a partir da Constituição Federal de 1988
Authors: Rocha Emanuela Cardoso , Silva Yara Dayane de Lira , Marques Jacyara Farias Souza , Wanderley Helmara Giccelli Formiga , Silva Rosilene Agra da , Vieira Maria Marques Moreira
Published: September 2023

A presente pesquisa trata da agroindústria familiar como um dos sustentáculos que propiciam o fortalecimento da agricultura familiar abordando, em específico, as dificuldades enfrentadas pelo agricultor familiar no que tange ao processo de regularização das agroindústrias e os tipos de pessoas jurídicas em que esses produtores podem se enquadrar. O trabalho ainda aponta alguns dos requisitos exigidos pela legislação nacional no que se refere ao processo de regularização das agroindústrias familiares. A pesquisa teve como objetivo geral analisar os requisitos jurídicos para a regulamentação da agroindústria familiar apontando as exigências legais para a regularização das agroindústrias familiares e ainda identificando os tipos de pessoas jurídicas que as agroindústrias podem se enquadrar de acordo com cada situação individual. Para alcançar os objetivos propostos, a pesquisa utilizou uma revisão bibliográfica do tipo narrativa, onde os dados foram coletados por meio da análise de artigos, dissertações e teses (texto integral), publicados nas plataformas da CAPES, SCIELO, BDTDs, IBGE, FUNASA, SENAR, CONAB, CAIXA etc; bem como em seites de Revistas eletrônicas e no Google Academic; o critério de busca se deu por meio da utilização de palavras chaves correlacionadas diretas e indiretas com o estudo, com um lapso temporal dos últimos cinco anos, salvo a utilização de obras clássicas. Como resultado, observou-se que existem diversos benefícios que a regularização da agroindústria familiar traz para os agricultores familiares, por outro lado, em razão de processos complexos e dos entraves para alcançar essa regularização muitos agricultores familiares optam por permanecerem na informalidade.
Viabilidade do uso da nanocelulose bacteriana no tratamento de feridas induzidas em ratos wistar
Authors: Peralta Rafael Freitas Silva , Fernandes Sabrina Devoti Vilela , Cunha Guilherme Nascimento , Moreira Dulcídio Barros
Published: September 2023

Introdução: Desde a antiguidade, diversas modalidades de tratamento têm sido empregadas no manejo de feridas. Atualmente, curativos com nanocelulose bacteriana (NCB) destacaram como tratamento de lesões teciduais devido sua biocompatibilidade, capacidade de manutenção da umidade, estimulação de queratinócitos, fibroblastos e menores taxas de infecção. Objetivo: Analisar macroscopicamente e microscopicamente o processo cicatricial de feridas induzidas em ratos Wistar com uso de curativo com membrana de NCB. Métodos: Vinte ratos Wistar foram submetidos a duas incisões no dorso, correspondentes as Feridas Teste (FT), tratadas com o curativo de NCB, e Feridas Controle (FC), tratadas com gaze e solução fisiológica NaCL 0.9%. Os ratos foram distribuídos randômica e igualitariamente em quatro grupos de cinco ratos, de forma que G1 correspondeu ao grupo biopsiado 3 dias de pós-operatório, G2 em 7 dias, G3 em 14 dias e G4 em 21 dias. O material biopsiado foi utilizado para confeccionar lâminas histológicas coradas com Hematoxilina/Eosina e Tricrômico de Masson. Resultados:  Não se observou presença de exsudato purulento, hemorragia ou formação de abscessos em ambos os grupos. A contração das bordas das FT se deu de forma estatisticamente significativa (p<0,05) em relação às FC. As FT apresentaram menor resposta inflamatória, reepitelização e redução do número de fibroblastos mais precoce, formação e organização antecipada das fibras colágenas. Conclusão: O uso de curativo com NBC promoveu uma contração precoce das bordas da ferida, menor resposta inflamatória, maior atração de fibroblastos, formação de colágeno e organização das fibras colágenas, resultando em uma cicatrização mais rápida.
Análise do cenário nacional de transplantes no Brasil
Authors: Okano Cristiane da Silva , Menezes Carolina Caicó Sotero de , Brandão Felipe Antônio , Carletto Vanessa Raquel , Souza Mariza Aparecida de
Published: September 2023

O objetivo do estudo foi analisar o cenário panorâmico de transplantes de órgãos no Brasil entre os anos de 2018 e 2022. Estudo descritivo de abordagem quantitativa, com dados do Departamento de Informática e Registro Brasileiro de Transplantes, disponibilizado pelo Sistema Nacional de Transplante, com análise gráfica de variáveis numéricas de notificações de potenciais doadores, efetivação das doações, quantidade transplantes e recusa familiar, no período entre 2018 e 2022. No período de estudo, registraram-se 58.222 potenciais doadores e 17.367 doações efetivas, o Brasil ocupa a quarta posição em transplante renais e hepáticos. Quanto aos potenciais doadores a região Sul se destaca com maiores notificações e as regiões Norte e Nordeste com notificações inferiores. Já em relação as notificações de doadores efetivos a região Sul assumiu a liderança em termos de notificações, enquanto a região Norte possui as menores taxas, porém em 2022 destaca-se com aumento notável. Em relação ao número de transplantes, o rim se sobressai como maior órgão transplantado, por outro lado os órgãos intestino e multivisceral apresentam números limitados no período analisado. Por fim, as recusas familiares apresentaram variações entre o período de estudo e nota-se um aumento significativo no ano de 2022. O cenário de transplantes no Brasil mostra avanços, mas também desafios. Apesar de progressos nas taxas de doadores em certas regiões, a disparidade entre demanda e disponibilidade, junto a questões culturais e de informação, impactam o sistema. Conscientização, educação e políticas de saúde são vitais para garantir a acessibilidade e viabilidade da doação de órgãos.
El Antropoceno: Reflexiones para comprender la crisis ambiental.
Authors: Gracia López Edgar
Published: September 2023

En este escrito se sintetizan consideraciones referidas a categorías que inciden en las maneras como se reconocen, estructuran y organizan los conocimientos y sus formas de relacionamiento con la sociedad, la naturaleza y el ambiente. Se examinan las categorías de: Antropoceno, cambio climático, humanismo, transhumanismo, progreso, desarrollo. Estas son fundamentales e imprescindibles para aportar claridades sobre la llamada crisis civilizatoria y ambiental que vive la humanidad. Se mencionan asuntos que tienen que ver con el papel de la ciencia y la tecnología que atraviesa el amplio espectro de condiciones manifiestas en los diferentes órdenes: éticos, ambientales, económicos, sociales, culturales y biofísicos. Igualmente, se resalta la necesidad de construir y constituir un pensamiento ambiental integrador que potencie una propuesta ecológico-política que, con visión interdisciplinaria, aporte a la sustentabilidad como referente.
Youth Subculture Mathematical Modeling
Authors: Abroskina A. , Kolpak E.
Published: September 2023

Youth subcultures are inherent in all times, have a significant impact on the formation of the worldview of youth. Mathematical modeling of the self-organization of such associations allows us to estimate the time interval of their existence, filling with fans and other characteristics. Technical and material support help to form an understanding of the tasks of the future. The paper presents the results of a sociological survey of a large group of young fans of anime culture. Based on the analysis of the author’s statistical data, taking into account statistical data published in open sources, a mathematical model of the youth subculture has been developed, including several areas of close interest. The model is represented by the Cauchy problem for a system of ordinary differential equations. An analysis of the stability of stationary states is given. The conditions imposed on the parameters of the mathematical model that determine the disintegration of the subculture are determined.
Aeroallergens as Indicators of the Anthropogenic Triads
Authors: Kobzar V. , Osmonbaeva K.
Published: September 2023

The growing interest in the complex issue of climate change, environmental pollution and aeroallergens is reflected in the queries of Internet users in various search engines. Recently, articles have been published on the impact of changes in the traditional land use system on the concentration and species composition of plant pollen and fungal spores. The total effects of the influence of the anthropogenic triad on plant pollen and fungal spores: 1) an increase in the time of the beginning of the growth of plants and fungi and, consequently, the beginning of their production; 2) earlier terms and lengthening of the pollination season; 3) an increase in the concentration and species composition of pollen of allergenic plants and fungal spores in the air of the regions, especially in the urban environment, along vertical zonality in mountainous conditions; 4) modification, deformation, fragmentation of pollen grains; 5) change in allergenic potential: increase in the number of allergens in pollen; 6) transformation of allergens in fungal spores; 7) change in the geospatial distribution of plant pollen and fungal spores, i.e. transportation of whole pollen, its fragments and spores over long distances; 8) emergence in the regions, on a global scale of new species of allergenic plants and phytopathogens; 9) changes in the qualitative and quantitative composition of pollen and aerospores, due to a change in the traditional system of land use, sowing of new cultivated plants and, accordingly, the introduction of new phytopathogens; 10) vegetation on the pollen of bacteria and fungal spores that change the structure of the pollen grain; 11) trigger effect of aeroallergens in the occurrence of allergic diseases in humans; 12) an increase in the number of indeterminate pollen and spore particles in aerobiological studies.
Allergy to Cannabis Pollen in a Changing World
Authors: Kobzar V.
Published: September 2023

Globally, the family of Cannabaceae (hemp) — dicotyledonous plants of the order Rosaceae Rosales (formerly the order Urticales nettle) includes two allergenic genera, namely: hemp and hops. It is estimated that only one male cannabis flower produces about 350,000 pollen grains, and if the plant includes hundreds of flowers, then it gives a lot of pollen in the air, carried far enough. Given that marijuana is legalized as a light drug in many countries, the effects of Cannabis on health, including allergies, are coming to the forefront of medical research and interest. As an aeroallergen, hemp pollen causes allergic rhinitis, allergic keratoconjunctivitis, hypersensitive pneumonitis and exacerbation of bronchial asthma symptoms. Cannabis is one of the oldest cultures of mankind, and records of its use in food, fiber, medicine and intoxication date back more than 6,000 years. Until 1965, hemp was grown in Kyrgyzstan as a technical crop for the production of bags, twine and ropes. The Pasture Department of the Ministry of Agriculture suggests returning to the cultivation of cannabis, and as the agricultural cannabis industry grows, Cannabis sativa may also become a more serious aeroallergen. According to the State Drug Control Service, now wild cannabis grows in the country on an area of 2,617 hectares, which is equal to the area of 12 Monaco. Hemp pollen is not among the top ten global aeroallergens, but it has common features: small size, similar morphology, high pollen production. The purpose of the presented article was to conduct palynomorphological studies of native cannabis pollen, classify the identified teratomorphoses and evaluate the standardized contribution of cannabis to the aerobic situation. Biomonitoring of cannabis pollen from various observation points in Kyrgyzstan using light and scanning electron microscopy revealed 4 types of teratomorphoses of varying degrees of complexity: 1) deformation; 2) perforation; 3) fragmentation; 4) complex changes in the sculptural elements of the exina surface. Using a standardized pollen contribution index, the potential contribution of Cannabaceae pollen to the aerobic situation of observation points in Kyrgyzstan was assessed. It is based on the following indicators: the timing of flowering, the size of pollen grains (polar axis and equatorial diameter), the abundance of growing species in the region and pollen production.
Effect of Potash Fertilizers on Changes in Some Physiological Parameters of Beetroot (Beta vulgaris var. esculenta Salisb.) under Absheron Conditions
Authors: Makhsudov Sh.
Published: September 2023

During the years of research, depending on the norms of fertilizers, the leaf surface area, the content of chlorophyll in the leaves, the photosynthetic potential of the sowing field, the coefficient of economic efficiency of photosynthesis, the specific surface density of the leaves, the total wet and dry biomass were studied plants, and the results were subjected to statistical processing and their level of reliability was assessed. The introduction of organic and mineral fertilizers for beetroot plants has a positive effect on the leaf surface area, the value of photosynthetic potential, the indicators of coefficient of economic efficiency of photosynthesis and specific surface density of the leaves, as well as on the amount of total dry and wet biomass.
Cultivation Factors Effect on the Hashimi Variety Rice Efficiency
Authors: Islamzadeh T.
Published: September 2023

The main agrochemical indicators of the experimental field in the Lankaran-Astara economic region having dark gray soils have been presented in the article. The results of the analysis showed that the pH in the tillage layer of the experimental field is 6.12-5.87, in the lower layers, this figure ranged from 5.98 to 6.20. That is, the area has a weakly acidic property. There is no carbonation here as the pH of the experimental field soils is below 6.5. The experimental lands in the Lankaran-Astara economic region are considered to be of good quality. Because the amount of humus is 3.03-3.14% in the tillage layer, and 1.63-1.73% and 1.05-1.06% in the lower layers. At a depth of 0-30 cm of the analyzed soils, the amount of mobile phosphorus (P2O5) varied on average from 30.9 to 34.1 mg per 1 kg of soil, and the exchangeable potassium varied between 317 and 327 mg. The field is moderately supplied with mobile phosphorus and exchangeable potassium. The highest indicator was obtained in the first decade of May, at the rate of 1.7 million seedlings per hectare and nutrition condition N120P80K60.
Features of Education of Tolerance of Young Schoolchildren
Authors: Taghiyeva R.
Published: September 2023

Currently, humanity is divided into different societies called states. Although not all states are multinational, they are multicultural. History and current events clearly prove that no society has yet been recorded as being based on tolerance in relationships, civil solidarity and individual respect. In this regard, the problem of tolerance is considered important both at the international and national levels. Tolerance is a complex social-pedagogical, philosophical phenomenon that has different meanings within the spheres of knowledge of different people, and at the same time it is an ethical-philosophical concept, a socio-cultural phenomenon, a socio-political solution method, a principle of mutual relations between people. Junior school age is a sensitive period of tolerance education. In children, this age period is more intensive in the process of general development of personality.
The Role of Trade Routes and Local Markets in the Economic Life of the Surkhan Oasis
Authors: Kabulov E. , Kabulov K.
Published: September 2023

In this article, the overland trade routes that existed in the Beks of Eastern Bukhara in the 18th-20th centuries, what products played the main role in the daily needs of the residents of the oasis, the role of trade relations in the economic, socio-political life of the Beks, were described based on the principles of comparative analysis and historical sequence through historical sources.
Differences in Expressions of Retrospective and Prospective Categories (In the Aspect of Artistic Text)
Authors: Biygeldieva N.
Published: September 2023

Retrospection is considered as a grammatical category of the text that organizes the reader’s understanding of the content-factual information presented in front, which is a kind of linguistic expression. A prospectus is a speech element that provides meaningful and factual information that has the ability to recreate and plan it. This is a constructive method that informs the reader (listener) about what information will be in advance in the process of discussing the subject of speech. The categories of retrospection and prospection interpret the main idea of the author in a literary text in close connection with the compositional structure of the work and its reception by the individual reader.
Rumeli’de Suhte(Softa) Olayları ve Anadolu İle Karşılaştırmalı Bir Bakış (1566-1609)
Authors: ÇAĞ Galip
Published: September 2023

Suhte ya da softa olayları Osmanlı klasik çağının son bölümünde ortaya çıkan ve 16. yüzyılın sonuna dek evvela Anadolu’da etkisini gösteren mühim bir toplumsal hadisedir. Bahse konu tarih aralığında çok ciddi bir asayiş sorunu haline gelen olayların hemen tüm Osmanlı coğrafyasını bu denli etkilemesi de ayrıca önemli ve ilginçtir. Zira bu denli geniş çaplı bir halk hareketinin kısa sayılabilecek sürede gösterdiği yaygınlık meseleyi sosyolojik bir hadise haline getirir.

Suhte olayları her ne kadar Anadolu’da Celali İsyanlarının bir ön safhası gibi düşünülse de kayıtlar hadiselerin özellikle de Rumeli’de de karşılık bulduğunu gösterir. Dolayısı ile konu sadece bir Anadolu hareketi değil Osmanlı topraklarının tamamını ilgilendiren bir vaka olarak düşünülmelidir.

Suhte isyanları, Osmanlı tarihi açısından çok önemli olmakla birlikte, bölgesel çalışmalar dışında bütüncül bir incelemeye tabi tutulmamıştır. Özellikle isyanların coğrafik özellikleri bu manada çalışılmaya muhtaçtır. Bu çalışmanın ana gayesi de isyanların Rumeli boyutunu incelerken Anadolu ile arasındaki ilişki ve farklılıkları sosyolojik açıdan değerlendirmektir. İncelemede hadiselerin erken dönem kökleri ortaya konulduktan sonra hadisenin bir asayiş sorunu olarak toplumsal karşılığı da izah edilecektir.

Suhte ya da softa olayları Osmanlı klasik çağının son bölümünde ortaya çıkan ve 16. yüzyılın sonuna dek evvela Anadolu’da etkisini gösteren mühim bir toplumsal hadisedir. Bahse konu tarih aralığında çok ciddi bir asayiş sorunu haline gelen olayların hemen tüm Osmanlı coğrafyasını bu denli etkilemesi de ayrıca önemli ve ilginçtir. Zira bu denli geniş çaplı bir halk hareketinin kısa sayılabilecek sürede gösterdiği yaygınlık meseleyi sosyolojik bir hadise haline getirir.

Suhte olayları her ne kadar Anadolu’da Celali İsyanlarının bir ön safhası gibi düşünülse de kayıtlar hadiselerin özellikle de Rumeli’de de karşılık bulduğunu gösterir. Dolayısı ile konu sadece bir Anadolu hareketi değil Osmanlı topraklarının tamamını ilgilendiren bir vaka olarak düşünülmelidir.

Suhte isyanları, Osmanlı tarihi açısından çok önemli olmakla birlikte, bölgesel çalışmalar dışında bütüncül bir incelemeye tabi tutulmamıştır. Özellikle isyanların coğrafik özellikleri bu manada çalışılmaya muhtaçtır. Bu çalışmanın ana gayesi de isyanların Rumeli boyutunu incelerken Anadolu ile arasındaki ilişki ve farklılıkları sosyolojik açıdan değerlendirmektir. İncelemede hadiselerin erken dönem kökleri ortaya konulduktan sonra hadisenin bir asayiş sorunu olarak toplumsal karşılığı da izah edilecektir.
Otoprotective Mechanisms of Carvone As An Antioxidant Agent Against Ototoxic Damage Caused By Paclitaxel
Authors: DİNCER Büşra , ATALAY Fatma , TATAR Arzu
Published: September 2023

Objective: Ototoxicity is cellular damage caused by the use of solid treatments as chemotherapeutics in critical illnesses like cancer. The generation of free radicals is linked to fluctuating hearing loss caused by chemotherapeutics. Antioxidants can help to prevent ototoxicity-related oxidative damage. Carvone (CVN) is a monoterpene with excellent antioxidant properties that protect against oxidative damage. This study investigates the biochemical and functional aspects of CVN’s putative otoprotective mechanisms against paclitaxel (PCX)-induced ototoxicity.

Methods: 24 Wistar albino rats were assigned into four different groups: Control, CVN, PCX, and PCX+CVN. Once a week, the control group received saline. The PCX group received 5 mg/kg PCX intraperitoneally once a week (4 times). Once a week, the CVN group received 50 mg/kg intraperitoneally. The PCX+ CVN group received 5 mg/kg PCX followed by 5 mg/kg CVN once a week. All animals were subjected to deterioration product otoacoustic emission testing before (day 0) and after drug administration (day 23).

Results: PCX showed an ototoxic effect by weakening otoacoustic emission values. PCX leads to significant otoacoustic emission value shifts ameliorated by CVN co-treatment (for 2000Hz p< .001, for 4000 levels p< .01, for 6000Hz p< .001, and for 8000 Hz p< .01 in PCX+CVN group). Furthermore, the PCX group had significantly greater malondialdehyde levels and significantly lower glutathione levels in the cochlear tissues, compared to the other groups. Co-administered CVN with PCX reversed these effects, making oxidative stress parameters close to those of the control group (for GSH levels p< .001, for MDA levels p< .01 in the PCX+CVN group).

Conclusion: According to the findings, CVN appears to preserve cochlear function in rats against the disruptive effects of PCX.
Evaluation of the Clinical Effect of Hyaluronic Acid Mouthwash on Palatal Secondary Wound Healing in Diabetic Rats
Authors: AKÇE Ezgi , DEMİRCİ DELİPINAR Sibel , KURU Leyla , YILDIRIM Hatice Selin
Published: September 2023

Objective: The objective of this study was to investigate clinical effect of topically administered hyaluronic acid (HA) mouthwash on healing of secondary palatal wound in diabetic (D) rats.

Methods: 60 Wistar albino male rats were divided into D and non-diabetic (ND) groups. Diabetes was induced to 30 randomly selected rats by initially administering 110 mg/kg of nicotinamide intraperitoneally, followed by 15 min of intraperitoneal injection of 65 mg/kg of streptozotocin solution. 5 mm excisional wounds were made in the centre of the palate. After that, 6 animals from each group were sacrificed. Then, both groups were subdivided into two groups: 0.12% HA mouthwash and saline (S) (n=12 per group), depending on the agent to be administered to the wound area (WA). On days 7 and 14, six rats from each group were sacrificed, and the WAs were measured through photographic measurements utilizing Image J software.

Results: The WA decreased with time in each group (p
Formal verification of the pub-sub blockchain interoperability protocol using stochastic timed automata
Authors: Alam Md Tauseef , Halder Raju , Maiti Abyayananda
Published: September 2023

In recent times, the research on blockchain interoperability has gained momentum, enabling the entities from different heterogeneous blockchain networks to communicate with each other seamlessly. Amid the proliferation of blockchain ventures, for ensuring the correctness of inter-blockchain communication protocols, manual checking and testing of all the potential pitfalls and possible inter-blockchain interactions are rarely possible. To ameliorate this, in this paper, we propose a systematic approach to model and formally verify the real-time properties of the pub-sub interoperability protocol, with a special focus on message communication through API calls among publishers, subscribers, and brokers. In particular, we use stochastic timed automata for its modeling, and we prove its correctness with respect to a number of relevant properties using model checking—more specifically, the UPPAAL-SMC model checker. To the best of our knowledge, this is the first proposal of its kind to formally verify the blockchain pub-sub interoperability protocol using model checking.
The age of computational cardiology and future of long-term ablation target prediction for ventricular tachycardia
Authors: Moinuddin Arsalan , Ali Syed Yusuf , Goel Ashish , Sethi Yashendra , Patel Neil , Kaka Nirja , Satapathy Prakasini , Sah Ranjit , Barboza Joshuan J. , Suhail Mohammed K.
Published: September 2023

Ventricular arrhythmias, particularly ventricular tachycardia, are ubiquitously linked to 300,000 deaths annually. However, the current interventional procedure—the cardiac ablation—predict only short-term responses to treatment as the heart constantly remodels itself post-arrhythmia. To assist in the design of computational methods which focuses on long-term arrhythmia prediction, this review postulates three interdependent prospectives. The main objective is to propose computational methods for predicting long-term heart response to interventions in ventricular tachycardia Following a general discussion on the importance of devising simulations predicting long-term heart response to interventions, each of the following is discussed: (i) application of “metabolic sink theory” to elucidate the “re-entry” mechanism of ventricular tachycardia; (ii) application of “growth laws” to explain “mechanical load” translation in ventricular tachycardia; (iii) derivation of partial differential equations (PDE) to establish a pipeline to predict long-term clinical outcomes in ventricular tachycardia.
Pharmacological treatment of hypertension guided by peripheral or central blood pressure: a comparison between the two strategies
Authors: Guimarães Filho Gilberto Campos , de Oliveira Vitorino Priscila Valverde , Inuzuka Sayuri , Barroso Adriana Sebba , Pacífico Alves Filho Robson Pierre , Melo Victoria Alves , de Oliveira Urzeda Luiz Fernando , Lima Sousa Ana Luiza , Coca Antonio , Veiga Jardim Paulo César Brandão , Barroso Weimar Kunz Sebba
Published: September 2023

Background

Arterial hypertension treatment guided by central blood pressures (CPB) rather than peripheral blood pressures (PBP) measurement has the potential to show greater effectiveness in preventing or even regressing stiffness and target organ damage (TOD).

Objective

This study aimed to compare the parameters of CBP and PBP measurements, arterial stiffness, TOD and renal profile in patients with anti-hypertensive treatment guided by CBP or PBP targets.

Methods

A randomized clinical trial was conducted in central group (CG) and peripheral group (PG). Patients were randomized, evaluated every 3 months for BP and antihypertensive adjustments during a one-year follow up. The procedures in V1 and V5: anthropometric assessment; CBP/PBP measurements, carotid ultrasound; echocardiography; laboratory tests. Paired and unpaired t-tests and the χ2 were used (significance level: 5%).

Results

The study evaluated 59 participants (30CG/29PG). The augmentation index (AIx) was higher in the CG (27.3% vs. 20.3%, p = 0.041). Intergroup analysis has found central diastolic BP lower in the CG (78.9 vs. 84.3 mmHg, p = 0.024) and the Alx difference between groups ceased to exist after a one-year follow-up. Intragroup comparisons, after intervention, showed a lower frequency of changed PWV (p < 0.001) and LVMI (p = 0.018) in the CG. The PG showed a higher frequency of changed PWV (p < 0.001) and LVMI (p = 0.003).

Conclusion

The intervention guided by central BP reduced the central diastolic BP and AIx compared to the PG. There was a reduction in the frequency of changed PWV and LVMI in the CG.
Ongoing substrate-driven atrial fibrillation “boxed” in the left atrial posterior wall with ablation: a case report
Authors: Traykov Vassil , Marchov Daniel , Martinov Emiliyan , El Abbady Asmaa , Gelev Valeri , Dichtl Wolfgang
Published: September 2023

Patients undergoing valve surgery for rheumatic heart disease are expected to develop significant atrial arrhythmogenic substrates outside of the pulmonary veins, which sometimes require complex ablation techniques for the treatment of symptomatic arrhythmias. We describe, herein, the case of a 76-year-old male undergoing endocardial ablation for the treatment of symptomatic persistent atrial fibrillation which developed after aortic and mitral valve replacement with a simultaneous tricuspid ring annuloplasty. Following pulmonary vein isolation, the patient's atrial fibrillation was converted into cavotricuspid isthmus-dependent atrial flutter. After a successful cavotricuspid isthmus ablation, the arrhythmia reverted back to a left atrial tachyarrhythmia originating from the posterior wall. A linear left atrial lesion led to the electrical isolation of a large area, which included the posterior wall, as well as the containment of the ongoing fibrillatory activity, while sinus rhythm was restored in the rest of the atria. In conclusion, successful left atrial posterior wall isolation can be achieved in the setting of severe scarring due to previous atriotomy by creating a linear lesion on the atrial roof, in conjunction with pulmonary vein isolation, sparing the patient from requiring bottom-line ablation, and avoiding possible esophageal injury. Such compartmentalization of the left atrium may effectively contain local fibrillatory activity, while allowing for the restoration of sinus rhythm.
Accuracy assessment of quasi-seamless hydrographic separation models in Malaysian waters
Authors: Hamden Mohammad Hanif , Din Ami Hassan Md , Alihan Nur Surayatul Atikah , Pa’Suya Muhammad Faiz , Wijaya Dudy Darmawan , Che Cob Ahmad Sanusi
Published: September 2023

The hydrographic survey reduction using ellipsoid has been available since the advent of the global navigation satellite system (GNSS), with a potential to streamline operation and enhance bathymetric output. Spatially continuous separation surfaces connecting a chart datum (CD) to a geodetic ellipsoid is required for this technique. Universiti Teknologi Malaysia (UTM) has invented a new quasi-seamless separation model for Malaysian waters, known as the Malaysian Vertical Separation (MyVSEP) model, through semi-empirical models to capture the spatial variability of a tidal datum between coastal and offshore areas. A continuous vertical datum is established to develop MyVSEP models by combining the coastal and offshore datasets. The coastal datasets referred to the vertical reference point computed from coastal tide gauges, while the offshore datasets referred to the vertical reference surfaces derived from satellite altimetry. Mean sea level (MSL) or mean sea surface (MSS), mean dynamic topography (MDT), lowest astronomical tide (LAT), and highest astronomical tide (HAT) are the vertical datums involved in developing the continuous MyVSEP model. However, the integration of the vertical datum has only been conducted over the Peninsular Malaysia region. For Sabah and Sarawak, datum integration cannot be implemented due to the limitation of coastal datasets. The assessment of the integrated vertical datum with coastal tide gauges is discussed in this study. The finding shows that the root mean square error (RMSE) agreement between the integrated Universiti Teknologi Malaysia 2020 (iUTM20) model and coastal tide gauges yields below 2.0 cm. The iUTM20 lowest astronomical tide and highest astronomical tide models also show significant improvement compared to the altimetric-derived tidal models, which recorded the root mean square error agreement with coastal tide gauges of 1.8 cm and 2.0 cm, respectively. The development of a continuous vertical separation model for the Ellipsoidally Referenced Surveying technique indirectly optimizes marine geospatial information resources, especially for the National Hydrographic Centre in Malaysia.