bluuebunny/crossref_metadata_2025 huggingface dataset:
Recognition of Facial Emotion Expressions in Patients with Depressive Disorders: A Functional MRI Study
Authors: Ternovoy Sergey , Ustyuzhanin Dmitry , Shariya Merab , Beliaevskaia Alena , Roldan-Valadez Ernesto , Shishorin Rodion , Akhapkin Roman , Volel Beatrice
Published: February 2023

Background: The present study evaluated the cortical activation during emotional information recognition. Methods: The study group included 16 patients with depression, and 16 healthy subjects were enrolled as a control group. Patients received eight weeks of antidepressant therapy. Functional MRI evaluated the cortical activation twice in the patient group and once in the control group. The fMRI task processed the emotional information with face demonstration from the PennCNP test battery. Results: During the processing of emotional information, patients showed activation in the middle and the inferior frontal gyri, the fusiform gyrus, and the occipital cortex. After treatment, patients showed a significant decrease in the frontal cortex activation for negative face demonstration and no frontal activation for positive emotion recognition. The left superior temporal gyrus activation zone appeared in patients after treatment and in the control group. Healthy subjects showed more intense frontal cortex activation when processing neutral emotions and less when showing happy and sad faces. Activation zones in the amygdala and the insula and deactivation zones in the posterior cingulate cortex were revealed in the controls. Conclusion: This study confirms the hypothesis that anomalies in the processing of emotional stimuli can be a sign of a depressive disorder.
Uptake of Radionuclides by Bryophytes in the Chornobyl Exclusion Zone
Authors: Schmidt Brigitte , Kegler Felix , Steinhauser Georg , Chyzhevskyi Ihor , Dubchak Sergiy , Ivesic Caroline , Koller-Peroutka Marianne , Laarouchi Aicha , Adlassnig Wolfram
Published: February 2023

The “Chernobyl nuclear disaster” released huge amounts of radionuclides, which are still detectable in plants and sediments today. Bryophytes (mosses) are primitive land plants lacking roots and protective cuticles and therefore readily accumulate multiple contaminants, including metals and radionuclides. This study quantifies 137Cs and 241Am in moss samples from the cooling pond of the power plant, the surrounding woodland and the city of Prypiat. Activity concentrations of up to 297 Bq/g (137Cs) and 0.43 Bq/g (241Am) were found. 137Cs contents were significantly higher at the cooling pond, where 241Am was not detectable. Distance to the damaged reactor, amount of original fallout, presence of vascular tissue in the stem or taxonomy were of little importance. Mosses seem to absorb radionuclides rather indiscriminately, if available. More than 30 years after the disaster, 137Cs was washed out from the very top layer of the soil, where it is no more accessible for rootless mosses but possibly for higher plants. On the other hand, 137Cs still remains solved and accessible in the cooling pond. However, 241Am remained adsorbed to the topsoil, thus accessible to terrestrial mosses, but precipitated in the sapropel of the cooling pond.
Metabolic Evaluation of Synthetic Opioids on the Example of U-47700 with the Use of In Vitro and In Vivo Methods for Forensic Toxicology Application
Authors: Rojek Sebastian , Poljańska Ewa , Chaim Weronika , Maciów-Głąb Martyna , Bystrowska Beata
Published: February 2023

Legal highs present a great threat to health, especially in groups of people experimenting with psychoactive substances. The lack of available knowledge on the biotransformation of these substances necessitates symptomatic treatment in the event of intoxication, which, unfortunately, may be ineffective. Opioids, including heroin analogues, such as U-47700, constitute a special group of designer drugs. In this study, a multi-directional approach to trace the biotransformation of U-47700 in living organisms was used. For this purpose, the in silico assessment (ADMET Predictor) was used first and then followed by an in vitro study using human liver microsomes and the S9 fraction. The biotransformation was then followed in an animal model (Wistar rats). Tissues such as blood, brain and liver were collected for analysis. The study was performed using liquid chromatography with tandem mass spectrometry (LC-MS/MS). The obtained results were compared to those obtained from the analysis of autopsy materials (cases analysed in the Toxicology Laboratory of the Department of Forensic Medicine, Jagiellonian University Medical College in Krakow).
Investigation of Cu Adsorption and Migration with Spectral Induced Polarization in Activated Carbon
Authors: Bate Bate , Cao Jingjing , Yang Yixin , Cao Junnan , Zhang Chi , Zhang Shuai
Published: February 2023

In this paper, the adsorption process of copper ions on activated carbon (AC) was simulated in a column test. It was deduced that it is consistent with the pseudo-second-order model. Cation exchange was observed to be the major mechanism of Cu–AC interactions through scanning electron microscopy–energy dispersive X-ray spectroscopy (SEM–EDS), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR) measurements. Adsorption isotherms were fitted well using the Freundlich model. Adsorption thermodynamics at 298, 308, 318 K demonstrated that the adsorption process is spontaneous and endothermic. Spectral induced polarization (SIP) technique was used to monitor the adsorption process, and the double Cole–Cole model was used to analyze the SIP results. The normalized chargeability was proportional to the adsorbed copper content. Two measured relaxation times from the SIP testing were converted into the average pore sizes of 2, 0.8, 0.6, 100–110, 80–90, and 53–60 µm by the Schwartz equation, which are consistent with the measured pore sizes from both mercury intrusion porosimetry and scanning electron microscopy (SEM). The reduction in the pore sizes by SIP during the flow-through tests suggested that the adsorbed Cu2+ gradually migrated into small pores as with continued permeation of the influent. These results showcased the feasibility of using SIP technique in engineering practice involving the monitoring of copper contamination in land near a mine waste dump or in adjacent permeable reactive barriers.
Effects of Initial pH and Carbonate Rock Dosage on Bio-Oxidation and Secondary Iron Mineral Synthesis
Authors: Fu Yuran , Zhang Ruixue , Wang Neng , Wu Pan , Zhang Yahui , An Li , Zhang Yuhao
Published: February 2023

The effect of pH is a key factor in biomineralization mediated by Acidithiobacillus ferrooxidans to promote the transformation of Fe into secondary iron minerals. This study aimed to investigate the effects of initial pH and carbonate rock dosage on bio-oxidation and secondary iron mineral synthesis. Variations in pH and the concentrations of Ca2+, Fe2+, and total Fe (TFe) in the growth medium of A. ferrooxidans were examined in the laboratory to determine how they affect the bio-oxidation process and secondary iron mineral synthesis. The results showed that in systems with an initial pH of 1.8, 2.3, and 2.8, the optimum dosages of carbonate rock were 30, 10, and 10 g, respectively, which significantly improved the removal rate of TFe and the amount of sediments. At an initial pH of 1.8 and a carbonate rock dosage of 30 g, the final removal rate of TFe reached 67.37%, which was 28.03% higher than that of the system without the addition of carbonate rock, and 36.9 g·L−1 of sediments were generated, which was higher than that of the system without the addition of carbonate rock (6.6 g·L−1). Meanwhile, the number of sediments generated by adding carbonate rock were significantly higher than those without the addition of carbonate rock. The secondary minerals were characterized by a progressive transition from low crystalline assemblages composed of calcium sulfate and subordinated jarosite, to well crystal-line assemblages composed of jarosite, calcium sulfate, and goethite. These results have important implications for comprehensively understanding the dosage of carbonate rock in mineral formation under different pH conditions. The findings help reveal the growth of secondary minerals during the treatment of AMD using carbonate rocks under low-pH conditions, which offers valuable information for combining the carbonate rocks with secondary minerals to treat AMD.
Boosting In-Vivo Anti-Tumor Immunity with an Oral Microparticulate Breast Cancer Vaccine and Low-Dose Cyclophosphamide
Authors: Mulla Nihal , Chablani Lipika , Parenky Ashwin C. , D’Souza Martin J.
Published: February 2023

Tumor cells express antigens that should induce immune-mediated rejection; however, spontaneous rejection of established tumors is rare. Recent evidence suggests that patients suffering from cancer exhibit an elevation in regulatory T cells population, a subset of CD4+ T cells, which suppress tumor recognition and elimination by cytotoxic T cells. This study investigates immunotherapeutic strategies to overcome the immunosuppressive effects exerted by regulatory T cells. A novel immunotherapeutic strategy was developed by simultaneous administration of oral microparticulate breast cancer vaccines and cyclophosphamide, a regulatory T cell inhibitor. Breast cancer vaccine microparticles were prepared by spray drying, and administered orally to female mice inoculated with 4TO7 murine breast cancer cells in combination with a low dose of intraperitoneally administered cyclophosphamide. Mice receiving the combination of vaccine microparticles and cyclophosphamide exhibited maximal tumor regression and the highest survival rate compared with the control groups. This study highlights the importance of cancer vaccination along with regulatory T cell depletion in cancer therapy, and suggests that a low dose of cyclophosphamide that specifically and significantly depletes regulatory T cells may be a highly effective immunotherapeutic strategy for the treatment of cancer.
Safe Subunit Green Vaccines Confer Robust Immunity and Protection against Mucosal Brucella Infection in Mice
Authors: Abushahba Mostafa F. , Dadelahi Alexis S. , Lemoine Emily L. , Skyberg Jerod A. , Vyas Swati , Dhoble Sagar , Ghodake Vinod , Patravale Vandana B. , Adamovicz Jeffrey J.
Published: February 2023

Brucellosis is a zoonotic disease that causes significant negative impacts on the animal industry and affects over half a million people worldwide every year. The limited safety and efficacy of current animal brucellosis vaccines, combined with the lack of a licensed human brucellosis vaccine, have led researchers to search for new vaccine strategies to combat the disease. To this end, the present research aimed to evaluate the safety and efficacy of a green vaccine candidate that combines Brucella abortus S19 smooth lipopolysaccharide (sLPS) with Quillaja saponin (QS) or QS-Xyloglucan mix (QS-X) against mucosal brucellosis in BALB/C mice. The results of the study indicate that administering two doses of either sLPS-QS or sLPS-QS-X was safe for the animals, triggered a robust immune response, and enhanced protection following intranasal challenge with S19. Specifically, the vaccine combinations led to the secretion of IgA and IgG1 in the BALF of the immunized mice. We also found a mixed IgG1/IgG2a systemic response indicating evidence of both Th1 and Th2 activation, with a predominance of the IgG1 over the IgG2a. These candidates resulted in significant reductions in the bioburden of lung, liver, and spleen tissue compared to the PBS control group. The sLPS-QS vaccination had conferred the greatest protection, with a 130-fold reduction in Brucella burdens in lung and a 55.74-fold reduction in the spleen compared to PBS controls. Vaccination with sLPS-QS-X resulted in the highest reduction in splenic Brucella loads, with a 364.6-fold decrease in bacterial titer compared to non-vaccinated animals. The study suggests that the tested vaccine candidates are safe and effective in increasing the animals’ ability to respond to brucellosis via mucosal challenge. It also supports the use of the S19 challenge strain as a safe and cost-effective method for testing Brucella vaccine candidates under BSL-2 containment conditions.
Assessment of GO-Based Protein Interaction Affinities in the Large-Scale Human–Coronavirus Family Interactome
Authors: Bandyopadhyay Soumyendu Sekhar , Halder Anup Kumar , Saha Sovan , Chatterjee Piyali , Nasipuri Mita , Basu Subhadip
Published: February 2023

SARS-CoV-2 is a novel coronavirus that replicates itself via interacting with the host proteins. As a result, identifying virus and host protein-protein interactions could help researchers better understand the virus disease transmission behavior and identify possible COVID-19 drugs. The International Committee on Virus Taxonomy has determined that nCoV is genetically 89% compared to the SARS-CoV epidemic in 2003. This paper focuses on assessing the host–pathogen protein interaction affinity of the coronavirus family, having 44 different variants. In light of these considerations, a GO-semantic scoring function is provided based on Gene Ontology (GO) graphs for determining the binding affinity of any two proteins at the organism level. Based on the availability of the GO annotation of the proteins, 11 viral variants, viz., SARS-CoV-2, SARS, MERS, Bat coronavirus HKU3, Bat coronavirus Rp3/2004, Bat coronavirus HKU5, Murine coronavirus, Bovine coronavirus, Rat coronavirus, Bat coronavirus HKU4, Bat coronavirus 133/2005, are considered from 44 viral variants. The fuzzy scoring function of the entire host–pathogen network has been processed with ~180 million potential interactions generated from 19,281 host proteins and around 242 viral proteins. ~4.5 million potential level one host–pathogen interactions are computed based on the estimated interaction affinity threshold. The resulting host–pathogen interactome is also validated with state-of-the-art experimental networks. The study has also been extended further toward the drug-repurposing study by analyzing the FDA-listed COVID drugs.
Heterologous Prime-Boost Vaccination with Commercial FMD Vaccines Elicits a Broader Immune Response than Homologous Prime-Boost Vaccination in Pigs
Authors: Kim Jaejo , Lee Seung-Heon , Kim Ha-Hyun , Park Jong-Hyeon , Park Choi-Kyu
Published: February 2023

Three commercial vaccines are administered in domestic livestock farms for routine vaccination to aid for foot-and-mouth disease (FMD) control in Korea. Each vaccine contains distinct combinations of inactivated serotype O and A FMD virus (FMDV) antigens: O/Manisa + O/3039 + A/Iraq formulated in a double oil emulsion (DOE), O/Primorsky + A/Zabaikalsky formulated in a DOE, and O/Campos + A/Cruzeiro + A/2001 formulated in a single oil emulsion. Despite the recommendation for a prime-boost vaccination with the same vaccine in fattening pigs, occasional cross-inoculation is inevitable for many reasons, such as lack of compliance with vaccination guidelines, erroneous application, or change in vaccine types by suppliers. Therefore, there have been concerns that a poor immune response could be induced by cross-inoculation due to a failure to boost the immune response. In the present study, it was demonstrated by virus neutralization and ELISA tests that cross-inoculation of pigs with three commercial FMD vaccines does not hamper the immune response against the primary vaccine strains and enhances broader cross-reactivity against heterologous vaccine antigens whether they were applied or not. Therefore, it could be concluded that the cross-inoculation of FMD vaccines can be used as a regimen to strategically overcome the limitation of the antigenic spectrum induced by the original regimen.
Molecular Tracking of the Origin of Vesicular Stomatitis Outbreaks in 2004 and 2018, Ecuador
Authors: Vasco-Julio David , Aguilar Dayana , Maldonado Alexander , de la Torre Euclides , Cisneros-Montufar Maria Soledad , Bastidas-Caldes Carlos , Navarro Juan-Carlos , de Waard Jacobus H.
Published: February 2023

The Vesicular Stomatitis Virus (VSV) is an arbovirus causing vesicular stomatitis (VS) in livestock. There are two serotypes recognized: New Jersey (VSNJV) and Indiana (VSIV). The virus can be transmitted directly by contact or by vectors. In 2018, Ecuador experienced an outbreak of Vesicular Stomatitis (VS) in cattle, caused by VSNJV and VSVIV, with 399 cases reported distributed over 18 provinces. We determined the phylogenetic relationships among 67 strains. For the construction of phylogenetic trees, the viral phosphoprotein gene was sequenced, and trees were constructed based on the Maximum Likelihood method using 2004 outbreak strains from Ecuador (GenBank) and the 2018 sequences (this article). We built a haplotype network for VSNJV to trace the origin of the 2004 and 2018 epizootics through topology and mutation connections. These analyses suggest two different origins, one related to the 2004 outbreak and the other from a transmission source in 2018. Our analysis also suggests different transmission patterns; several small and independent outbreaks, most probably transmitted by vectors in the Amazon, and another outbreak caused by the movement of livestock in the Andean and Coastal regions. We recommend further research into vectors and vertebrate reservoirs in Ecuador to clarify the mechanisms of the reemergence of the virus.
Effect of Electrolysis Parameters on the Fractal Structure of Electrodeposited Copper
Authors: Wu Na , Zhang Chunxia , Han Shanyu , An Juan , Xia Wentang
Published: February 2023

Models based on diffusion-limited aggregation (DLA) have been extensively used to explore the mechanisms of dendritic particle aggregation phenomena. The physical and chemical properties of systems in which DLA aggregates emerge are given in their fractal. In this paper, we present a comprehensive study of the growth of electrodeposited copper dendrites in flat plate electrochemical cells from a fractal perspective. The effects of growth time, applied voltage, copper ion concentration, and electrolyte acidity on the morphology and fractal dimension of deposited copper were examined. ‘Phase diagram’ set out the variety of electrodeposited copper fractal morphology analysed by metallographic microscopy. The box counting method confirms that the electrodeposited dendritic structures manifestly exhibit fractal character. It was found that with the increase of the voltage and copper ion concentration. The fractal copper size becomes larger and its morphology shifts towards a dendritic structure, with the fractal dimension fluctuating around 1.60–1.70. In addition, the morphology of the deposited copper is significantly affected by the acidity of the electrolyte. The increase in acidity from 0.01 to 1.00 mol/L intensifies the hydrogen precipitation side reactions and the overflow path of hydrogen bubbles affects the fractal growth of copper dendrites.
Exploración del potencial para aprender Álgebra a través del descubrimiento y generalización de Patrones
Authors: Palma Luis Rolando Padilla , Lagos Evelin Johana , López Lilian Nohemy , Izaguirre Josué Alejandro
Published: February 2023

El siguiente documento contiene, de manera breve, la fundamentación teórica, sobre la que hemos concebido como base para justificar la aplicación del proyecto de investigación, y algunos resultados sobre el proyecto el cual trata sobre la exploración del potencial del alumno de 7mo grado de aprender algebra a través del descubrimiento y generalización de patrones, que es el foco del proyecto, teniendo en cuenta las implicaciones históricas, cognitivas, pedagógicas y didácticas.
Estudo do compósito de borracha natural com fibra de bagaço de cana-de-açúcar
Authors: Brandão Veridiany Rejane Pereira , Peres Lucas Salomão , Da Silva Leandro Cardoso
Published: February 2023

Atualmente a fibra de bagaço de cana-de-açúcar tem sido estudada para a utilização de reforço em outros materiais para a redução da poluição atmosférica e ambiental, oriunda da queima de resíduos industriais. O presente trabalho visou um comparativo das propriedades mecânicas da borracha natural virgem (NR) com o compósito da borracha natural reforçado com de fibra de bagaço da cana-de-açúcar (NR/BCA). Para se obter o compósito, o bagaço de cana-de-açúcar foi moído, peneirado em mesh 150, tratado com hidróxido de sódio a 10% e incorporado na borracha em proporção de 30 phr (per hundred rubber) em um misturador aberto de cilindros, segundo a norma ASTM D 3182. Os corpos de prova foram produzidos conforme a norma ASTM D 412 Tipo C, para a realização dos ensaios mecânicos de tração e dureza Shore A, de acordo com a norma ASTM D 2240. Contudo, os resultados esperados são que conforme a inserção da fibra na matriz polimérica da borracha natural (NR) a característica de flexibilidade se mantenha e que a resistência da deformação na ruptura do material aumente, possibilitando que o compósito seja utilizado na preparação de sandálias.
Un modelo para el seguimiento de cursos de capacitación
Authors: Pérez Alejandro Felipe Zárate , De La Mota Idalia Flores
Published: February 2023

El seguimiento de un curso en línea es de vital importancia para el desarrollo de este, ya que un seguimiento adecuado puede lograr que un curso alcance el objetivo de que finalicen la mayor cantidad de alumnos el mismo. Sin embargo, realizar este monitoreo en diversos cursos al mismo tiempo puede ser una labor muy compleja si no se tienen las herramientas adecuadas. En este trabajo se presenta un modelo para el seguimiento / monitoreo de cursos, desde una perspectiva de analíticas de la enseñanza, donde el seguimiento se realiza a los encargados de impartir el curso. Asimismo, se analizan los datos obtenidos por el modelo y se infieren las causas encontradas a través un análisis visual de los mismos.
Diversidade na escola: os caminhos da política de inclusão escolar no contexto do semiárido brasileiro
Authors: Dos Santos Viviane Brás , Dos Reis Ana Cecília
Published: February 2023

O presente artigo teve por objetivo geral analisar como as políticas de inclusão podem favorecer a promoção do Atendimento Educacional Especializado - AEE no contexto escolar do semiárido brasileiro. Com o foco de responder nossa problemática que resultou no objetivo realizamos uma pesquisa sendo que a proposta metodológica seguiu os princípios da pesquisa qualitativa com a utilização do estudo bibliográfico. A partir das leituras minuciosas relacionadas à temática central em diversas fontes como artigos, periódicos eletrônicos, Leis, livros entre outros, conseguimos subsídios teóricos que deram fundamentação conceitual e epistemológica para nossa reflexão. Sabe-se que  a inclusão de pessoas com necessidades educacionais especiais ainda é um dilema no Brasil e que embora, existam leis que garantam o Atendimento Educacional Especializado – AEE, identificamos que essa realidade caminha em passos lentos em todo o país, inclusive no Semiárido Brasileiro cujos territórios ainda são carentes de tais políticas públicas.
Managerial Planning in Disaster Logistics: Model Proposal for Logistics Administrative Structuring in Pandemics
Authors: KÜÇÜK Burak
Published: February 2023

In disaster management, it is necessary to make strategic, tactical and operational plans, determine goals and targets, organize necessary to reach these goals, and find resources. Logistics planning is done according to the numbers and basic needs of the victims. The problems experienced in local production and international transportation during the COVID-19 Pandemic process, which started in China and affected the whole world, and which is a type of biological disaster, caused disruptions in supply chains. The effectiveness of medical intervention and disaster management studies in pandemics depends on the efficiency of logistics services. The COVID-19 pandemic has demonstrated the importance of logistics planning specific to pandemic response activities, in line with Turkey's disaster response structure and legislation. Disaster and emergency legislation in Turkey, disaster management systems in different countries and pandemic response studies were also examined. Based on the literature research and face-to-face interviews, suggestions were made regarding the administrative structure of the institutions and organizations working at the command, tactical or operational levels in the pandemic response. By evaluating the response studies in the COVID-19 pandemic, an administrative structuring model was created for logistics activities in pandemics.
Analisis Pelaksanaan ANBK Ditinjau Dari Hasil Literasi Membaca Dan Literasi Numerasi Pada Siswa Sekolah Dasar
Authors: Wulan Sari Septi , Arnidha Yunni
Published: February 2023

Program yang baru pertama kali akan dilaksanakan di seluruh sekolah baik dasar maupun menengah membuat pihak sekolah dan juga guru mengalami kebingungan mengenai persiapan hingga pelaksanaan ANBK. Kendala utama yang dialami yaitu ada pada aspek teknologi dan sarana prasarana yang mengakibatkan kendala pada ANBK seringkali terjadi dan perlu adanya upaya yang tepat untuk menanggulanginya. Tujuan penelitian ini adalah untuk mengetahui analisis pelaksanaan ANBK yang ditinjau dari literasi membaca dan literasi numerasi. Metode penelitian ini ialah menggunakan metode penelitian kualitatif deskriptif. Metode penelitian deskriptif ialah metode yang melibatkan proses konseptual dan menghasilkan pembentukan skema-skema klarifikasi. Teknik pengumpulan data menggunakan observasi dan wawancara dengan menggunakan uji data triangulasi yaitu membandingkan data wawancara dan observasi dengan data pendukung lainnya agar data lebih kredibel. Hasil dari penelitian ini adalah pelaksanaan ANBK di sekolah dasar satu gugus ahmad dahlan kecamatan kalirejo kabupaten lampung tengah ialah kelima sekolah dasar masih mencakupi level  perlu adanya intervensi khusus dan dasar pada literasi membaca dan numerasi yang disebabkan oleh dua faktor yaitu internal ada pada guru dan siswa sedangkan faktor eksternal ada pada sekolah dan teknologi
Digitalisasi Ekonomi Sirkular di Indonesia
Authors: Salim Ahmad Ramdani
Published: February 2023

ABSTRACT

Circular economy is an economic concept based on a closed loop in which all processes strive to reuse resources, raw materials, and finished products for as long as possible while producing as little waste or waste as possible. This concept applies the 5R principle, which stands for Reduce, Reuse, Recycle, Recovery, and Repair. The economic circular's discussion is closely related to the goals and agreements reached at the G20 meeting in Bali on November 15-16, 2022. In order to implement this circular economy with significant and contemporary economic added value, efforts must be made to accelerate digitization of all channels and aspects of the circular economy. This community service program is carried out through direct and interactive exposure methods to stakeholders supported by information processing through a qualitative literature review. The circular economy will have a positive impact on the environment as well as the financial aspects as a result of this digitization, and its utilization is expected to touch all related elements in an integrated manner. The government and all stakeholders, particularly in Indonesia, face a challenge in gaining a comprehensive understanding of circular economy digitization.
DC vacuum arc deposition with open winding-path anode assembled with C-ring plates
Authors: Bando Takahiro , Saiki Yoshinori , Kito Jumpei , Hashimoto Yuki , Harigai Toru , Takikawa Hirofumi , Gima Hiroki , Sugita Hiroaki
Published: February 2023

Vacuum arc deposition (VAD), which utilizes the vapored high energy metal ions from an electrode, is widely used in industry. Though VAD has many advantages, the reduction of droplets on deposited films is an essential issue to solve for its industrial application. In this study, we have developed a new type of filtered arc deposition (FAD) utilizing a winding coil with copper C-ring-shaped plates in a vacuum chamber. TiN films were deposited on substrates with a normal linear FAD and the new FAD. TiN films were analyzed, and it was found that the number of droplets was significantly reduced with the new FAD.
الحوكمة في شعر الصلتان العبدي (القصيدة العينية أنموذجا )
Authors: د.ملاذ ناطق علوان  , م.د ديلم كاظم سهيل
Published: February 2023

المفارقة هي الفرق والافتراق والفصل والتباعد والتباين والتمييز بين شيئين أو امرين او موقفين... لاسيما إِذا كان هذان الأمران على طرفي نقيض، أو أحدهما خلاف الآخر، او بالضد منه... ولعل هذا المعنى يبقى أحادياً، مالم يردف بالمعنى الأصطلاحي بالمفارقة حتى يستقيم طرفا المعادلة – اي المفارقة من كلتا زاويتي الرصد.وبحصر المعان والدلالات والمفاهيم قديمها وحديثها عن معنى المفارقة الاصطلاحي نصل إلى إنها (( أسلوب بلاغي عالي التقنية، أساسه عرض وجهتي نظر متعادلتين ، متعارضتين متضادتين ، بين مفهوم عام شائع واخر ذاتي فكري ، وكلما أشتد التضاد بينهما برزت المفارقة ،
المصدر أنواعه ، ورتبة معموله
Authors: د. حقّيّ إسماعيل الجبوريّ
Published: February 2023

الحمد لله حمدا يليق بعظمته وجلاله، وأفضل الصّلاة وأتمّ التّسليم على النّبيّ الكريم؛ محمّد بن عبد الله، وآله الطّيّبين الطّاهرين وصحبه المنتجبين.

هذا بحث بعنوان (المصدر .. أنواعه ورتبة معموله) وهو في الدّراسات النّحويّة، وقد اهتمّ البحث بإظهار تعريف المصدر وحدّ أنواعه الثّلاثة، وبحث بالتّفصيل جوانب رتب عوامله تقديما وتأخيرا، سواء كان المصدر مأخوذا من فعل لازم أم من فعل متعد، وقد عُزّز الكلام في البحث بأقوال النّحويّين المتقدّمين في حال الإيجاب والنّفي، كما ناقش البحث مقولات للنّحويّين بهذا الخصوص، معتمدا في ذلك على النّصّ القرآنيّ الكريم أساسا في الاستشهاد والرّدّ، ثمّ على أبيات من الشّعر، ثمّ الأمثلة المصنوعة، هو بحث في جزئيّة من النّحو العربيّ معتمدا على مصادر ومراجع متنوّعة خدمة للباحثين والدّارسين.
A RETROSPECTIVE STUDY ON IATROGENIC BILE DUCT INJURY OF 16 PATIENTS AT TERTIARY CARE CENTRE
Authors: Patel Saket , R. Modi Pankaj , Parakhiya Akshay , Patel Shashank
Published: February 2023

Iatrogenic bile duct injuries are less common complication of hepatobiliary surgery specially after laparoscopic
cholecystectomy but when occurs commonly due to misinterpretation of surgical anatomy, it requires early diagnosis
and management,which decreases morbidity and mortality and improve patient's quality of life.Different classification
of bile duct injuries according to site and extent are discussed as well as early diagnosis and appropriate intervention
like endoscopic, radiologic, and surgical approaches. Our aim of this study is to review the management challenges
depending on the time of recognition of the injury and extent of injury
A COMPARATIVE STUDY OF PROXIMAL FEMORAL NAILING VERSUS DYNAMIC HIP SCREW IN SURGICAL MANAGEMENT OF INTERTROCHANTERIC FRACTURES CONDUCTED AT ONE OF THE TERTIARY CARE HOSPITALS IN LUCKNOW
Authors: Seervi Rakesh , Kumar Pathak Susheel , Garg Uttam , Modi Amul
Published: February 2023

Introduction: Proximal femoral Fractures are a subset of fractures that occur in the hip region and occupy large
proportion of hospitalization amongst trauma cases.An overwhelming majority of these patients (>90%) are aged above
50 years. These are classified on the basis of anatomic location for example, femur neck fracture; inter trochanteric
fracture and subtrochanteric fracture.Therefore,the aim of the present study was to achieve fracture union by using two
different kinds of internal fixation modality devices in similar type of fractures. Material and Methods: This is a
randomized prospective study of 40 cases of intertrochanteric fractures,admitted to Career Institute of Medical Science,
Lucknow.All fractures were classified by the Seinsheimer classification system.The patients were treated with proximal
femoral nailing (PFN) and/or dynamic hip screw (DHS) and were categorised randomly into two groups, each of 20
patients, 20 were treated by dynamic hip screw and 20 were treated with proximal femoral nail (PFN). Results: The
intraoperative parameters were in favour of PFN with significantly less duration of surgery,length of incision and blood
loss but more fluoroscopy time.Postoperatively also,PFN group patients excelled with significantly less post-operative
pain, less incidence of deep infection, less mean limb length discrepancy and more patients regaining their pre injury
walking capability with also fewer complications. Conclusion: PFN emerged to be superior to DHS in unstable
intertrochanteric fractures.Intramedullary implants have been quite effective in sub-trochanteric fractures and should
be preferred better than extra-medullary plate fixation systems.
THE STABILIZED DUNES: A PILOT STUDY ON THE EFFECT OF ACACIA TORTILIS ON GROUND VEGETATION, FROM THAR DESERT, INDIA
Authors: Sen Monali , Kumar Shalabh
Published: February 2023

In modern days, sand dune stabilization works are very common in desert areas globally. The purpose is multifaceted;
developmental needs, soil moisture conservation works, and prevention of desert spread being the main among them. In
the Indian state of Rajasthan, the same works have been ongoing for a long in the Thar desert, primarily by the forest
department. This study was aimed as a non replicated administrative study, which has reflected on the possible
correlation between the stabilization work by afforestation and gradual loss of native shrub species of desert ecosystem
as found from the pilot sites. The preliminary findings of this study were then verified against previous research and
findings in other arid regions of the world. Simple counting of standing tree and shrub species was done from 1 sq. m.
sample plots of both forest department plantation sites and non-forest land areas. It was found that area with matured
grown Acacia tortilis has less ground coverage than other areas. Arid ecosystem has unique survival adaptations, the fast
growth of an introduced foreign species impacting the native ground cover can be due to multiple ecological reasons. A
much broader replicated study is necessary to ascertain this fact and thereby take necessary measures for preserving
both the desert ecosystem and enhance the sand stabilization works
IMPACT OF COVID - 19 IN RENAL TRANSPLANT RECIPIENT – A CASE REPORT
Authors: Guptha.L.R Srinivasa , M Jagadeesan. , Karthik. S Prasanna , Ezhilarasi Ezhilarasi
Published: February 2023

SARS-CoV-2 has been a pandemic which began in 2019. The clinical presentation of COVID-19 is highly variable and
ranges from asymptomatic infection to severe pneumonia, cytokine storm, and death. The prevalence of morbidity and
mortality due to Covid – 19 were notably higher in people with co-morbidities, and several studies have documented the
same. Renal transplant recipients are more susceptible for infections especially in this pandemic time. The mortality is
very high in such patients, as they are on immunosuppressive agents. We report a case of covid – 19 infection in a renal
transplant recipient.
INTUSSUSCEPTION -A RARE SURGICAL OCCURRENCE IN SCHOOL AGE CHILDREN
Authors: Cosmas Achebe Chijioke , Kayode Aremu Shuaib , Idris Salawu Adedayo , O Abiyere Henry , Adewale Olajide Timothy , Rasaq Adewoye Kayode
Published: February 2023

A case of a 12yr old female student who presented with a week old history of abdominal pain, vomiting, and bloodstained stool and was diagnosed by ultrasonography and barium enema to have intussusception (ileocolo colic variety).
Idiopathic cause, a diagnosis of exclusion was made at surgery. She was managed successfully and subsequently
followed up at the clinic.
AN ANALYTICAL NOTE ON THE STATUS OF AGRICULTURE SECTOR IN INDIAN ECONOMY
Authors: S. Kondekar Sagar
Published: February 2023

In the last 75 years of the Indian economy,more than 50 programmes were introduced for the agriculture and rural sector.
In this scenario,it really becomes appropriate to study the current status of Indian agriculture which is the priority sector
in India. This paper is an attempt to analyse the status of Indian agriculture which occupies the highest portion of the
Indian labour force. The present study describes the different programmes implemented for agriculture and rural
development in the previous 75 years.Moreover,the paper describes the trend of the share of the agriculture sector in
Gross Value Added and the rate of growth of agriculture.It also evaluates the production trend of agricultural products,
fisheries and livestock
A STUDY ON IMPROVED PATIENT OUTCOMES IN SEPTIC SHOCK WITH USE OF HYDROCORTIS
Authors: Desai Viraj , V . Mehta Prashant , RS Anusha , Mali Paresh
Published: February 2023

Management of sepsis is a time critical procedure; the consequences of improperly managed sepsis and septic
shock can cause multiple organ dysfunction and death. The aim of this study was to evaluate of the role of
hydrocortisone.
Ÿ Sepsis is dened as life-threatening condition causing multi-organ dysfunction by a dysregulated host response to
infection. Septic shock is a subset of sepsis with circulatory and cellular or metabolic dysfunction associated with a
higher risk of mortality .
Ÿ Sepsis is said to effect the hypothalamic pituitary adrenal axis, causing a relative adrenal insufficiency resulting in
cardiovascular instability,metabolic disorders,and a sustained pro- inammatory state.
Ÿ The role of pro-inammatory pathways suggests a potential use for corticosteroids as an adjuvant therapy in the
treatment of sepsis and septic shock .The Surviving Sepsis campaign guidelines recommend that if adequate uid
resuscitation and vasopressors have not restored the hemodynamic stability,it was postulated in limited data to use
inj hydrocortisone 100mg i/v 8 hourly for 7 days .
Ÿ There was an improvement in the overall survival and reduction in the mortality and morbidity of patients, as
observed by early weaning off from vasopressor support,reduction in total leucocyte counts
A CASE REPORT ON TREATMENT OF KIENBOCK'S DISEASE BY IMPLANTATION OF VASCULAR PEDICLE AND BONE GRAFTING
Authors: Patel Nishant , Patel Jyotish , Vyas Vaibhav
Published: February 2023

Numerous literatures have described various procedures in the treatment of Kienbock's disease depending upon the
severity of the symptoms, patient characteristics and radiological staging. These range from conservative management
to surgical procedures. The case under study had Lichtman stage ** disease. Vascularised bone grafts provide improved
blood flow, osteocyte preservation, and accelerated healing rates. We inserted pronator quadratus pedicled bone graft
into our case of lunate osteonecrosis and temporarily fixed the graft. Clinically, the patient reported pain subsidence
with improvement in range of motion and grip strength. Vascularised pedicle and bone grafting is an effective way for
treatment of early and middle stages of osteonecrosis of lunate
MARKETING STRATEGIES OF DABUR AMIDST SHIFT IN CONSUMER BEHAVIOR TOWARDS
AYURVEDIC PRODUCTS DURING COVID-19
Authors: Bhargava Madhulika , Joshi Amrita , Joshi Manvik
Published: February 2023

Covid 19 pandemic has crucially affected the economy, health and other spheres of life. This unprecedented pandemic
has severely affected consumer attitudes, behaviorism, and purchasing habits.The rapid shifts in consumer behavior
patterns have major implications on consumer goods industries. Now, most of the purchases are centered on basic needs
specially health and nutrition for general well-being. In present situation, consumers are fascinated towards health and
immunity boosters. Personal health and hygiene has become a top priority of the people.People are changing their
buying preferences based on global circumstances, the product categories being purchased are also changing. The
market is also flooded with immunity boosters especially Ayurvedic products, hygiene and sanitizing solutions.. The
most important change that this pandemic has brought in the consumer behavior is that they are now moving from
reactive to proactive mindsets and because of Ayurveda there will surely a sales boost in those kind of products as
consumer focus and priorities shifting towards inner health and immunity. Major players in the Indian market include
Dabur India Limited, Himalaya Drug Company Private Limited, Patanjali Ayurved Limited, Shree Baidyanath Ayurved
Bhawan Private Limited, Charak Pharma Private Limited, Emami Limited, Vicco laboratories. These key players are
building Ayurveda as a brand through their innovative marketing strategies and giving a boost to the Ayurveda sector.
Before Covid, the situation goes the same for the companies but this pandemic makes a change in the concept of
consumerism. Consumerism is also looking for new aspects as only dumping and increasing consumption of products is
not the way for the future. Now consumers are more focused on saving money, saving health and saving for the future.One
more new concept is emerging with it is adjusting to a New Normal which means a new way of living and going about our
lives, work and interactions with other people. The factors that influence brand decisions are also changing as a "buy
local" trend accelerates. Vocal for a local tagline has also created an emphasis on local products rather than wellestablished brands.Digital commerce has also seen a boost as new consumers migrate online for grocery shopping – a
rise that is likely to be sustained post-outbreak. This paper focuses on the shift in buying behavior of consumer towards
Ayurvedic products and changing marketing strategies of Ayurvedic companies specially Dabur in India in alignment
with consumer preferences
CORRELATION OF FINE NEEDLE ASPIRATION CYTOLOGY AND HISTOPATHOLOGY OF SOLITARY THYROID NODULE
Authors: Rakshit Sanchita
Published: February 2023

Fine needle aspiration cytology is commonly used to screen lesions in pathology including thyroid lesions.It is mainly
used to identify malignant lesions which then can be excised and examined by histopathology. FNAC uses the
cytological features to distinguish between benign and malignant lesions. In our study, 60 patients were taken, age
ranging from 15 to 65 years. Initially patients were clinically evaluated and FNAC followed by histopathological
examination was performed on the excised thyroid lesions.In our study, majority were females and neck swelling was
the commonest presentation. Majority were benign lesions. Malignant lesions were 18%.While comparing lesions in
FNAC and histopathology, sensitivity of FNAC was found to be 84.61% and specificity to be 93.61%. The accuracy of
FNAC obtained was 91.6 %.Thus,sensitivity and specificity of FNAC was high and can be used to screen thyroid solitary
nodules
MORTALITY PROFILE AND ITS CORRELATION WITH BPEWS SCORE IN PEDIATRIC INTENSIVE
CARE UNIT OF TERTIARY CARE CENTRE
Authors: Mauskar Anupama , Khadija Tabshir Shaikh , Inamdar Nusrat
Published: February 2023

Introduction: The care of critically ill children remains one of the most demanding and challenging aspects in the field
of Pediatrics. In spite of availability of well-equipped Pediatric Intensive Care Units (PICU), deaths do occur.
Aims/objective:To study the mortality profiles and its correlation to the Bedside Pediatric Early Warning System Score
(BPEWS) in children who expired within 48 hours of admission.Inclusion criteria:children aged1 month to 12 years who
expired within 48 hours of admission in PICU of a tertiary care center.Methods:Approval from the institutional ethics
committee was obtained prior to commencement of the study.Retrospective data of consecutive children aged 1 month
to 12 years who expired within 48 hours, was collected from the hospital's Medical Records Section. The variables
necessary for BPEWS Score calculator were noted and the BPEWS Score was calculated. Result: 84% patients were
below five years of age with mean age of 2.6 year and 57% were females. Mean duration of stay was 19.68 hours. Mean
distance from health facility was 8.31 km. Respiratory system was affected in the majority of patients (47%). More than
forty percent of children were undernourished. Mean BPEWS score was 17.36 in the age group of 1 to 5 year, which
depicts poor outcome. Conclusion: Majority of early deaths (within 48hrs) occurred in patients less than five years of
age.Higher BPEWS (>8) was associated with shorter duration of stay of patients and poor outcome
LUMBAR MRI FINDINGS IN SUDANESE PATIENTS WITH LOWER BACK PAIN
Authors: Abdelkreem Saida , Habeeb Eman , Abdalla Rahma , Siddig Afraa
Published: February 2023

Objective: Lower back pain is a very common health problem worldwide and a major cause of disability affecting
performance at work and general well-being.Also it is highly prevalent and has substantial socioeconomic implications.
The aim of this study was to find out the most common MRI findings in lumbar spine of Sudanese patients with lower back
pain and its relation to the patients age,gender and body mass index (BMI ). Materials and Methods:Total 104 patients
with lower back pain from both gender and aged between (11-80) years were scanned for lumbar spine MRI at (Abdoon
Seed Ahmed Medical Complex,and Alzaytoona Hospital),in a period from July 2021 to March 2022 were enrolled in the
study.The data were collected from medical reports using data collecting sheet and were analyzes by SPSS. Results:
The study found that the most common MRI findings were disc bulge (67.6%),followed by loss of lordosis (48.9%), and
the most affected level was L4-L5.MRI findings was not affected with patients age and gender,on other hand the lumbar
disordrers were significantly affected by patients BMI (P-value= 0.00). Conclusion: The study showed that lumbar
disorder was affected with patient BMI,but there was no significant variation nor with age neither with gender
Hubungan Frekuensi Kunjungan Keluarga Terhadap Status Depresi Pada Lansia di Panti Werdha Kristen Hana
Authors: Darmada Putu Dewinta , Tadjudin Noer Saelan
Published: February 2023

Abstrak:

Latar Belakang:

Depresi pada lansia yang tinggal di panti werdha merupakan akibat dari rasa kesepian dan kurangnya kunjungan keluarga, disamping penurunan kondisi fisik yang dialami. Penelitian ini bertujuan mengetahui hubungan frekuensi kunjungan keluarga dengan status depresi lansia di Panti Werdha Kristen Hana.

Metode:

Studi analitik cross sectional dengan consecutive sampling, responden sebanyak 55 orang lansia. Pengumpulan data dengan wawancara menggunakan Geriatric Depression Scale 15 question (GDS-15 - Short form).

Hasil:

Proporsi lansia jarang dikunjungi dan mengalami depresi 40%, sedangkan pada lansia sering dikunjungi dan mengalami depresi 25%. Hasil uji chi-square didapatkan p-value = 0,260 dan hasil uji epidemiologi didapatkan PRR = 1,6.

Simpulan:

Tidak didapatkan hubungan antara frekuensi kunjungan keluarga terhadap status depresi pada lansia di Panti Werdha Kristen Hana.

 

Kata Kunci: Depresi, lansia, kunjungan keluarga, panti werdha

Fundings: -
Seorang penderita syok anafilaktik dengan manifestasi takikardi supraventrikular
Authors: Pemayun Tjok Prima Dewi , Suryana Ketut
Published: February 2023

Syok anafilaksis termasuk kondisi kegawatdaruratan dengan penanganan yang cepat dan tepat untuk mencegah kematian. Manifestasi pada syok anafilaksis dapat muncul dalam berbagai organ salah satunya sistem kardiovaskuler. Telah dilaporkan kasus perempuan 18 tahun dengan keluhan lemas dan berdebar setelah 4 jam mengkonsumsi makanan tertentu. Pada pemeriksaan fisik ditemukan pasien dengan tekanan darah turun 70/palpasi dan frekuensi nadi 145x per menit, regular dan isi kurang. Pada gambaran EKG ditemukan takikardi supraventrikular. Diagnosis berdasarkan kriteria Samson adalah pasien datang dengan kondisi syok yang merupakan salah satu dari tiga kriteria yaitu pasien datang dengan penurunan tekanan darah lebih dari 90 mmHg atau penurunan lebih dari 30% dari tekanan darah sebelumnya segera setelah pasien terpapar bahan alergen tanpa penyebab syok lainnya. Manifestasi sistem kardiovaskuler yang muncul adalah takikardi supraventricular unstable dengan penatalaksanaan syok anafilaksis adalah pemberian epinefrin sebanyak 2 kali, resusitasi cairan dengan infus NaCl 0,9% dan dilakukan kardioversi 50 joule karena hemodinamik yang tidak stabil.