bluuebunny/crossref_metadata_2025 huggingface dataset:
AGE CHARACTERISTICS OF THE ORGANISM OF CHILDREN AND ADOLESCENTS IN THE CONDITIONS OF THE ARAL REGION
Authors:   Doctor Of Biological Sciences Associate Professor Of The Department Of Anatomy, Physiology And Biochemistry Of Animals, Samarkand State University Of Veterinary Medicine, Animal Husbandry And Biotechnology, Nukus Branch, Uzbekistan, Tlepovich Esimbetov Adilbay , Muratbayevich Rzaev Rakhat ,   Assistant Of The Department (Phd) "Anatomy, Physiology And Biochemistry Of Animals" Samarkand State University Of Veterinary Medicine, Animal Husbandry And Biotechnology, Nukus Branch, Uzbekistan, Xayratdinovna Maulenova Dilfuza ,   Karakalpak State University Named After Berdakh, 3rd Year Student In Biology, Uzbekistan, Jaksymbaevna Abdieva Tursinay ,   Karakalpak State University Named After Berdakh, Freelance Researcher, Uzbekistan
Published: April 2023

The article deals with the issues of the physical characteristics of the organism of children and adolescents. It is noted that the level of development of the qualities of motor activity and the degree of adaptability of the organism to physical loads are in close connection with age.
TRADITIONS AND INNOVATIONS IN HANDICRAFTS OF THE POPULATION
Authors:   Lecturer Department Of Archaeology, Faculty Of History, National University Of Uzbekistan, M. Koyliev Ravshon , Abdullaev Ilyos ,   Lecturer Department Of “Sports Law, Social And Natural-Scientific” Sciences Uzbek State University Of Physical Culture And Sport, Uzbekistan
Published: April 2023

This article describes in detail the characteristics of handicrafts in the economic life of our country, the role of handicrafts in it, the types of handicrafts carried out by the population, the specific characteristics of the development of this industry, the role of handicrafts in the formation and development of the inhabited area.
READING ACTIVITIES BASED ON USING RESOURCES OF THE CORPUS LINGUISTICS
Authors:   Master Degree Student, Uzbekistan State University Of World Languages, Uzbekistan, Tolmasova Khursantosh Anvar Kizi
Published: April 2023

In this article Corpora, in the sense “databases that contain texts”, are a widely used tool in language research. This tool can be a helpful resource for language teachers and learners as well, and many corpora are available online. In this chapter, Hilde Hasselgard discusses the use of corpora in the English classroom. She explains what a corpus is, and what answers a corpus can provide to questions about language use. Then she presents various possibilities for making use of corpora in language learning
Algorithm for managing older patients with syncope based on the guidelines of the European Society of Cardiology «Syncope» published in the Russian Journal of Cardiology in 2019
Authors: Tkacheva O. N. , Kotovskaya Yu. V. , Eruslanova K. A. , Alimova E. R.
Published: April 2023

Syncope is a short-term transient loss of consciousness associated with a decrease or cessation of blood supply to the brain. Syncope is one of the causes of falls in older patients, leading to increased hospitalizations and deaths. There is  an  increased  susceptibility to  syncope  with advancing  age and sometimes it  occurs with no  identifiable cause. Orthostatic hypotension, carotid sinus syndrome, neuromediated syncope, structural heart disease, and cardiac arrhythmias are the common contributors to  syncope in  older adults. Given the high risk in  this group of  patients, a structured and integrated approach to the management of older patient with syncope is required. Implementing the algorithm for the management of such patients allows us to evaluate the syncope cause, assess the risk and choose the optimal treatment for older patients.
Lithium is a new pole of attraction to the Kola region
Authors:   Federal Research Centre “Kola Science Centre of the Russian Academy of Sciences”, Tananaev Ivan G. , Krivovichev Sergey V. ,   Federal Research Centre “Kola Science Centre of the Russian Academy of Sciences”, Mudruk Sergey V. ,   Geological Institute of the Kola Science Centre of the Russian Academy of Sciences, Dub Alexey V. ,   Science and Innovations, Vernigora Artem S. ,   Science and Innovations
Published: April 2023

A review of the geological structure of the Kolmozerskoe lithium deposit is given. Information is given on the relevance of geological and mineralogical studies and searches for technologies for enrichment and processing of spodumene ore from the Kolmozersky lithium deposit, initiated by the FRC KSC RAS and ARRICT.
Acid decomposition of perovskite in a reactor with submersible electrodes
Authors:   I. V. Tananaev Institute of Chemistry and Technology of Rare Elements and Mineral Raw Materials  of the Kola Science Centre of the Russian Academy of Sciences, Artemenkov Anatoly G. , Gerasimova Lidia G. ,   I. V. Tananaev Institute of Chemistry and Technology of Rare Elements and Mineral Raw Materials  of the Kola Science Centre of the Russian Academy of Sciences, Bychenya Yulia G. ,   I. V. Tananaev Institute of Chemistry and Technology of Rare Elements and Mineral Raw Materials  of the Kola Science Centre of the Russian Academy of Sciences, Kuznetsova Elena V. ,   I. V. Tananaev Institute of Chemistry and Technology of Rare Elements and Mineral Raw Materials  of the Kola Science Centre of the Russian Academy of Sciences
Published: April 2023

It is shown that sulfuric acid decomposition of a mixture of perovskite (PC) and sphene (SC) concentrates obtained from the complex raw materials of the Kola Peninsula containing Ti, Nb, Ta, REM, etc., can be carried out both in classical types of chemical reactors with heat supply through heat exchange surfaces in the form of shirts, heating elements, and electric current using submersible metal electrodes. The parameters of the processes in which the extraction of titanium (IV) into sulfuric acid solutions reaches 85-90% are established.
Sulfuric acid technology for processing serpentinites with obtaining magnesium sulphate septahydrate
Authors:   «ГК “Русредмет”», Zhukov Stanislav V. , Nechaev Andrey V. ,   «ГК “Русредмет”», Chemekov Andrey M. ,   «ГК “Русредмет”», Shestakov Sergey V. ,   «ГК “Русредмет”»
Published: April 2023

The paper presents the developed technology for the processing of serpentinite by the sulfuric acid method.The technology provides for the following operations: sulfuric acid leaching of serpentinite, purification from impurities of a magnesium-containing solution and isolation of magnesium sulfate crystals. Also, the influence of the concentration of sulfuric acid on the degree of opening was established.
Effects of Mg-Zn substitution in the structure of layered double aluminum hydroxides on their physicochemical properties
Authors:   I. V. Tananaev Institute of Chemistry and Technology of Rare Elements and Mineral Raw Materials  of the Kola Science Centre of the Russian Academy of Sciences, Mayorov Dmitriy V. , Kopkova Elena K. ,   I. V. Tananaev Institute of Chemistry and Technology of Rare Elements and Mineral Raw Materials  of the Kola Science Centre of the Russian Academy of Sciences
Published: April 2023

Samples of Mg-Zn-Al layered double hydroxides were synthesized and studied by chemical, X-ray phase, BET and BJH assays. It was found that an increase in the degree of substitution of Mg by Zn leads to both an increase in the specific surface area and the specific volume of samples. At the same time, the distribution of mesopores has a polymodal character with a predominance of pores having dpores = 34 and 2550 nm.
Концентрирование фтористоводородной кислоты при переработке колумбитового и лопаритового концентратов
Authors:   GK “Rusredmet”, Orlov Alexander P. , Shchavelev Vladimir B. ,   GK “Rusredmet”, Migaenko Ekaterina S. ,   GK “Rusredmet”, Smirnov Alexander V. ,   GK “Rusredmet”, Nechaev Andrey V. ,   GK “Rusredmet”
Published: April 2023

The results of modeling the concentration of hydrofluoric acid on the example of processing columbite and loparite concentrates are presented. It is shown that when optimizing the rectification process, it is necessary to use the electrolyte NRTL vapor-liquid equilibrium model and use the total energy consumption going to the separation of the mixture as an optimization criterion. The information about the work on the extraction of anhydrous hydrogen fluoride from hydrofluoric acid is presented.
Pilot and industrial testing of the extraction technology for obtaining tantalum oxide from tantalum-containing residues
Authors:   GK ", Povetkin Kirill A. ,   Rusredmet", Novikov Mikhail L. ,   "PKF "Gefest", Smirnov Alexander V. ,   GK "Rusredmet", Nechaev Andrey V. ,   GK "Rusredmet"
Published: April 2023

This paper presents the results of testing the sulfate-fluoride extraction technology for obtaining tantalum oxide from tantalum-containing residues. The scheme of extraction purification of fluorotantalic acid from the solution obtained after fluoride-sulfate opening of iron-titanium cake is shown. The modes of extraction purification of fluorotantalic acid, the content of tantalum in the raffinate and re-extract are shown.
Extraction of ruthenium from solutions of refining production using tributyl phosphate
Authors:   ʺGK ʺRusredmetʺ, Sibilev Aleksandr S. , Zaitseva Tatyana N. ,   ʺGK ʺRusredmetʺ, Karmannikov Vladimir P. ,   ʺGK ʺRusredmetʺ, Ryabukhin Egor A. ,   ʺUralintechʺ
Published: April 2023

The extraction of ruthenium from the nitrite solution at different concentrations of tributyl phosphate (TBP) was investigated. It has been established that undiluted TBP is an effective extractant for extracting the element from solution. The possibility of deep purification of the ruthenium extract from impurity platinum metals by washing the saturated organic phase with a solution of sodium nitrite was showed. It was revealed that a high degree of ruthenium stripping is achieved using an alkali solution.
Features of the extraction sulfuric acid-fluoride technology for processing niobium- and tantalum-containing raw materials
Authors:   GK “Rusredmet, Smirnov Alexander V. , Zhukov Stanislav V. ,   GK “Rusredmet, Orlov Alexander P. ,   GK “Rusredmet, Nechaev Andrey V. ,   GK “Rusredmet
Published: April 2023

The results of researching of the leaching of niobium- and tantalum-containing raw materials by solutions of hydrofluoric and sulfuric acids are presented. Researching have been carried out on the solvent extraction purification and separation of niobium and tantalum from their fluoride-sulfuric acid solutions to obtain niobium oxides and tantalum oxides of the required quality using octanol-1 as an extractant. The possibility of recycling waste technological sulphate-fluoride solutions with the production of magnesium sulfate heptahydrate is shown. Information on the work on the use of pyrohydrolysis as a reagentless method for the isolation of products and the regeneration of hydrofluoric acid is presented.
Complex recycling of spent copper electrolyte
Authors:   I. V. Tananaev Institute of Chemistry and Technology of Rare Elements and Mineral Raw Materials of the Kola Science Centre of the Russian Academy of Sciences, Sokolov Artem Yu. , Shchelokova Elena A. ,   I. V. Tananaev Institute of Chemistry and Technology of Rare Elements and Mineral Raw Materials of the Kola Science Centre of the Russian Academy of Sciences, Vorontsov Konstantin A. ,   “Industrial Recycling Technologies” Ltd, Kasikov Alexandr G. ,   I. V. Tananaev Institute of Chemistry and Technology of Rare Elements and Mineral Raw Materials of the Kola Science Centre of the Russian Academy of Sciences
Published: April 2023

The paper presents data on obtaining valuable metal salts from the spent copper electrolyte. During its treatment, it is possible to produce copper, zinc sulfate solution, iron(III) oxide, nickel carbonate, and dilute sulfuric acid.
Nanofiltration method in the technology of uranium desorbate processing
Authors:   Tomsk Polytechnic University, Tyulyubaev Zekail M. , Leksin Alexei M. ,   Institute of High Technologies, Leonova Liliya A. ,   Tomsk Polytechnic University
Published: April 2023

The features of crystallization of cristobalite in quartz glass obtained on plasma torches of JSC "Dinur", the raw material for melting of which is quartz sand of the Ramenskoye mining and Processing Plant, are considered. On the high-temperature dilatometer DIL-402 of the company “Netzsch" (Germany), dependences of changes in the linear dimensions of quartz glass samples in various heating–cooling modes were obtained. The service process of refractory quartz ceramics made of opaque quartz glass is modeled.
PARTIAL COMPARATIVE METHODOLOGY ASSESSMENT OF THE LEVEL OF TECHNICAL PERFECTION SAMPLES OF MINE CLEARING TOOLS (COMPLEXES)
Authors: Lyashenko V. , Krivtsun V. , Kuznecov V. , Aheiev O.
Published: April 2023

With the beginning of the aggression of the russian federation against Ukraine in 2014, the territory of our country began to become a leader among the replaced countries of the world. The situation escalated with the beginning of the full-scale invasion of the russian federation in February 2022, and today’s Ukraine has become the country that is the most complicated in terms of explosive devices in the world. The enemy has been ignoring the requirements of international treaties and conventions regarding the prohibition of the use of certain types of mine weapons and uses the entire range of engineering ammunition available to him. One mine weapon is a major hazard from unexploded ordnance. In addition, during hostilities, one of the most difficult tasks is to provide military reconnaissance of the area for the presence of explosive objects, demining the area and passing through the changing fields of the enemy during the offensive. For the performance of these tasks, the staff structure of the engineering troops provides for appropriate units that are equipped with both equipment and hand-held reconnaissance and demining equipment. The protest and experience of the use of engineering units of the Defense Forces shows that the mentioned equipment, reconnaissance and demining are outdated, have low efficiency and do not meet the requirements for performing tasks of this type. At the same time, due to moral obsolescence and unsatisfactory state of means of exploration and mechanization, the manual method remains the main way of making passages in variable-explosive barriers. This method is extremely dangerous and contagious to the point of losing personnel.

In order to eliminate (mitigate) the mentioned problems, research is being conducted on the development of modern perspective demining complexes, both manual and remote-control. There are questions about their evaluation according to the level of technical excellence and efficiency during research.

The article offers one of the options for a partial method of comparative assessment of the level of technical perfection of samples of demining means (complexes) using methods of simulation modeling and a progressive standard. Assessment of the degree of compliance of alternatives to demining complexes is carried out by comparing them with a standard for which there is no state standard, and general requirements or quantitative indicators. Determining compliance with the requirements consists in comparing the comprehensive indicator of the evaluated alternatives of the demining complex with the comprehensive basic indicator.
BLUE PRINT PENGEMBANGAN LAYANAN INFORMASI KESEHATAN
Authors: Trisnanto Puguh Yudho , Lala Handy
Published: April 2023

Blue Print Pengembangan Lanyanan Informasi Kesehatan, merupakan bentuk cetak biru Pengembangan Layanan Informasi Kesehatan bagi organisasi RT.12.RW.02 Kelurahan Tunjungsekar Kota Malang. Cetak biru ini terdiri dari modul layanan kesehatan dari Inspirasi warga dan kebutuhan Layanan Informasi Kesehatan Warga di Masa Pandemi Covid-19 yang dibantu oleh Tenaga Kesehatan dari warga RT.12 RW.02 dalam Penyusunan Cetak biru Pengembangan Layanan Informasi Kesehatan. Tujuan Blue Print Pengembangan Lanyanan Informasi Kesehatan. Membantu program layanan informasi kesehatan Dinkes Kota Malang, yang bekerjasama dengan Puskesmas Mojolanggu sebagai Fasiliatas Pelayanan Kesehatan Tingkat 1, dengan cetak biru dari RT.12 RW.02 dapat membantu Pengembangan Program Layanan Kesehatan di Tingkat Kota Malang sesuai dengan program pemerintah, serta melibatkan Inspirasi masyarakat di Tingkat RT untuk memberikan monitoring program kesehatan pemerintah Kota Malang. Metode yang digunakan Metode DFD dimana Input, Proses, dan ouput yang dihasilkan. Di kontrol arus data informasi kesehatan yang digunakan oleh warga dan program kesehatan pemerintah pada umumnya. Metode ini juga mengurangsi informasi kesehatan yang tidak akurat dalam bentuk laporan hasil layanan informasi kesehatan yang digunakan. Kesimpulan hasil cetak biru ini mempercepat analisa Swot Kelemahan dan kekuatan Cetak biru Pengembangan Layanan Informasi Kesehatan, sehingga menghasilkan Aplikasi Kesehatan yang memiliki nilai guna manfaat dan nilai guna kebijakan program kesehatan pemerintah di Prosinsi Jawa Timur.
Estudio comparativo de la ganancia de peso de alevines de surubí (pseudoplatystoma sp.) con y sin adición de probiótico en el agua del estanque, en la estación de piscicultura de la entidad binacional Yacyretá, en la ciudad de Ayolas, durante el año 2020
Authors: Villalba Barrios Marcia Elizabeth
Published: April 2023

El presente trabajo de investigación se llevó a cabo en la Estación de Piscicultura de la Entidad Binacional Yacyretá ubicada en la Ciudad de Ayolas, Misiones. El objetivo de este trabajo fue comparar la ganancia de peso de alevines de Surubí (Pseudoplatystoma sp.) con y sin adición de probiótico en el agua del estanque durante 60 días. El diseño fue experimental con enfoque cuantitativo. Se utilizaron 240 alevines, distribuidos en dos grupos experimentales de 120 alevines para el estanque 1 (T1 sin probiótico) y 120 alevines para el estanque 2 (T2 con probiótico). El estanque 2 recibió una adición de 168 gr de probiótico en dos dosis de 84 gr cada 30 días. Como principales resultados se obtuvo: ganancia de peso de 17,7 gr en el T1 y 35,1 gr en el T2, presentado diferencia estadística significativa entre tratamientos. El índice de conversión alimenticia fue de 0,5 para ambos tratamientos. Los parámetros físico-químicos evaluados se encontraron dentro de los rangos aceptables para esta especie.
Evaluación histopatológica en modelo murino suplementado con creatina
Authors: Muñoz Pérez Valeria , Gutiérrez Hernández Rosalinda , López Jesús Adrián , Reyes Estrada Claudia Araceli , Argüelles Estrada Brenda Carolina , Muñoz Pérez Omar , Granados López Angélica Judith
Published: April 2023

La creatina es un nutriente natural, formado por tres aminoácidos (glicina, arginina y metionina), se puede sintetizar endógenamente en páncreas, hígado y riñón, o también se pude obtener dentro de la dieta con el consumo de alimentos de origen animal (carnes y pescado), el 95 por ciento de la creatina en el organismo se puede localizar en el musculo esquelético. El objetivo del trabajo fue determinar histológicamente el efecto de la creatina (ácido α-metil guanido-acético o monohidrato de creatina) en modelo murino. Como metodología se realizó un estudio experimental, longitudinal, analítico y descriptivo, se utilizaron 3 grupos de animales con 5 cada uno, en los cuales durante 60 días se probaron 3 diferentes dosis de creatina, al término del tiempo se sacrificaron y se obtuvieron medidas antropométricas y cortes histológicos. Los resultados arrojaron que existe obesidad en los grupos de estudio, en cuanto a la histología las imágenes microscópicas observadas de los grupos control no mostraron anormalidades globales en su morfología estructural, indicando que la manipulación y/o los tiempos de exposición no modificaron la arquitectura del musculo, intestino grueso, páncreas, hígado, riñón, piel, pulmón e intestino delgado. Se puede concluir que a las dosis utilizadas la creatina es segura.
A STUDY OF HOMOSEXUALITY IN ANCIENT GREECE WITH REFERENCE TO MADELINE MILLER’S THE SONG OF ACHILLES
Authors: N Madhusudan , Chowdhury Dr. Payel Dutta
Published: April 2023

Homosexuality has been a taboo in several parts of the world and continues to be so despite the vast changes that have revolutionized the lives of LGBTQIA+ community. But the question is, was it always a taboo? Were the classical societies ignorant of homosexuality? Or were they so accepting of it? Did they recognize and classify different sexual orientations? What was love between two individuals of the same gender like? This paper attempts to explore the nuances of homosexuality in ancient Greece with reference to Madeline Miller’s The Song of Achilles. With the theoretical framework of Foucault’s theory of sexuality, it aims to dissect the factors of homosexuality in ancient Greece, their ways of perceiving it, along with the character analysis of the protagonists in terms of masculinity and femininity. Understanding the notions of the fluid nature of gender and sexuality through retellings of classics like The Song of Achilles diversifies the readers’ relationship to literatures in being sensitive to queer community today.
RURAL URBAN DIVIDE IN TECHNOLOGY USAGE OF CONSUMERS IN BANKING INDUSTRY: A STUDY IN ASSAM
Authors: Boro Dr. Kamaleswar , Goswami Dr. Chandana
Published: April 2023

The study is an attempt to investigate the difference in terms of using different technology based banking services between rural and urban bank customers in India. The study findings reveal that, there is a distinct variation observed between rural and urban bank customers in terms of different technology based banking service usage, non-usage and not being aware of the services, frequency of usage, purposes of using, the extent of familiarity with computers, internet and smart phone usage. Urban customers can be considered as having high propensity to use different technology based banking services as their usage rate supersede non usage rate except for credit cards and M-Pesa. Urban bank customers are frequent users of technology based banking services whereas rural bank customers limit their use of these services to just fewer times a month.
PEMASANGAN IUD DAN IMPLANT SEBAGAI UPAYA MENINGKATKAN PEMAKAIAN METODE KONTRASEPSI JANGKA PANJANG (MKJP) DI MASA PANDEMI COVID-19
Authors: Sri Iriani Oktarina
Published: April 2023

Tujuan pengabdian masyarakat ini adalah untuk meningkatkan jumlah peserta KB MKJP dengan pemasangan Implant dan IUD. Metode pengabdian ini menggunakan studi lapangan, pemeriksaan langsung dengan langkah kegiatan; Penyuluhan, Pendidikan Kesehatan tentang KB MKJP IUD, Implant dan pemasangan Implant serta IUD. Kgiatan Pengabdian masyarakat dilakukan di wilayah pmb Bidan Rusmini Kota Bandung, dilaksanakan pada tanggal 17 Maret 2022. Hasil kegiatan pengabdian kepada masyarakat ini di ikuti oleh 28 akseptor yang terdiri dari 20 akseptor IUD dan 8 akseptor implant. Kegiatan Pengabdian dapat memberikan informasi kepada WUS serta memberikan kontribusi yang besar terhadap peningkatan jumlah peserta KB MKJP ( IUD dan Implant).
Manifestations of Moral Threats in the Ideosphere of Uzbekistan and Their Prevention Strategy
Authors: Sobirovich Turdiyev Bexruz
Published: April 2023

In some sources, it is recognized that globalization is a great threat to national culture, as well as contributing to the development of trade and cooperation between countries. So, in any case, there is an undeniable truth in all these thoughts, and at the same time, we have become their witnesses in life. This article analyzes moral threats in the ideosphere of Uzbekistan and the strategy of combating them.
Catching Tidal Dwarf Galaxies at a Later Evolutionary Stage with ALFALFA
Authors: Gray Laurin M. , Rhode Katherine L. , Leisman Lukas , Mancera Piña Pavel E. , Cannon John M. , Salzer John J. , Gault Lexi , Fuson Jackson , Józsa Gyula I. G. , Adams Elizabeth A. K. , Smith Nicholas J. , Haynes Martha P. , Janowiecki Steven , Pagel Hannah J.
Published: April 2023

We present deep optical imaging and photometry of four objects classified as “Almost-Dark” galaxies in the Arecibo Legacy Fast Arecibo L-band Feed Array (ALFALFA) survey because of their gas-rich nature and extremely faint or missing optical emission in existing catalogs. They have H i masses of 107–109
M
⊙ and distances of ∼9–100 Mpc. Observations with the WIYN 3.5 m telescope and One Degree Imager reveal faint stellar components with central surface brightnesses of ∼24–25

mag

arcsec

−
2

in the g band. We also present the results of H i synthesis observations with the Westerbork Synthesis Radio Telescope. These Almost-Dark galaxies have been identified as possible tidal dwarf galaxies (TDGs) based on their proximity to one or more massive galaxies. We demonstrate that AGC 229398 and AGC 333576 likely have the low dark matter content and large effective radii representative of TDGs. They are located much farther from their progenitors than previously studied TDGs, suggesting they are older and more evolved. AGC 219369 is likely dark matter dominated, while AGC 123216 has a dark matter content that is unusually high for a TDG, but low for a normal dwarf galaxy. We consider possible mechanisms for the formation of the TDG candidates such as a traditional major merger scenario and gas ejection from a high-velocity flyby. Blind H i surveys like ALFALFA enable the detection of gas-rich, optically faint TDGs that can be overlooked in other surveys, thereby providing a more complete census of the low-mass galaxy population and an opportunity to study TDGs at a more advanced stage of their life cycle.
Intraspecific divergence of diploid grass Aegilops comosa is associated with structural chromosome changes
Authors: Badaeva Ekaterina D. , Kotseruba Violetta V. , Fisenko Andnrey V. , Chikida Nadezhda N. , Belousova Maria Kh. , Zhurbenko Peter M. , Surzhikov Sergei A. , Dragovich Alexandra Yu.
Published: April 2023

Aegilops comosa Smith in Sibthorp et Smith, 1806 is diploid grass with MM genome constitution occurring mainly in Greece. Two morphologically distinct subspecies – Ae. c. comosa Chennaveeraiah, 1960 and Ae. c. heldreichii (Holzmann ex Boissier) Eig, 1929 are discriminated within Ae. comosa, however, genetic and karyotypic bases of their divergence are not fully understood. We used Fluorescence in situ hybridization (FISH) with repetitive DNA probes and electrophoretic analysis of gliadins to characterize the genome and karyotype of Ae. comosa to assess the level of their genetic diversity and uncover mechanisms leading to radiation of subspecies. We show that two subspecies differ in size and morphology of chromosomes 3M and 6M, which can be due to reciprocal translocation. Subspecies also differ in the amount and distribution of microsatellite and satellite DNA sequences, the number and position of minor NORs, especially on 3M and 6M, and gliadin spectra mainly in the a-zone. Frequent occurrence of hybrids can be caused by open pollination, which, along with genetic heterogeneity of accessions and, probably, the lack of geographic or genetic barrier between the subspecies, may contribute to extremely broad intraspecific variation of GAAn and gliadin patterns in Ae. comosa, which are usually not observed in endemic plant species.
Welfare et haute intensité : une tension au cœur des opérations navales
Authors: Lavernhe Thibault
Published: April 2023

L’usage quasi universel des smartphones constitue désormais un enjeu pour la sécurité des opérations navales. La notion de sillage numérique devient une problématique au regard de la dépendance croissante aux réseaux sociaux et à la connexion numérique. Cela exige une nouvelle discipline pour les équipages.
Les filières sucrières : un reflet des politiques publiques ?
Authors: Masson Timothé
Published: April 2023

Le sucre est un produit stratégique depuis le XVII e  siècle. Napoléon a structuré la filière à partir de la culture de la betterave avec un succès qui a perduré jusqu’au début du XXI e  siècle. Aujourd’hui, l’absence d’une politique publique entraîne des difficultés majeures au point de faire perdre à la France ses capacités de production.
Un an après l’invasion, une nouvelle phase du conflit
Authors: Dugoin-Clément Christine
Published: April 2023

Après un an de guerre, le conflit provoqué par la Russie contre l’Ukraine s’inscrit dans la durée. Les combats se sont figés sur une ligne de front où chaque partie s’efforce d’épuiser l’autre. Moscou, bien que responsable du chaos, essaye de faire porter la responsabilité à Kiev et à l’Otan, réécrivant de ce fait l’histoire.
L’emploi de la cyber-électronique en Ukraine
Authors: Wasielewski Jean-Marc
Published: April 2023

La cyber-électronique – appelée hier guerre électronique – joue un rôle important dans le conflit en Ukraine. Si les résultats russes sont en deçà de leurs ambitions, il reste difficile d’avoir un bilan précis des effets sur le terrain, l’Ukraine bénéficiant de l’appui occidental. Une certitude, la Chine observe avec attention.
La nécessité de faire évoluer le modèle du marché européen de l’électricité
Authors: Solier Boris
Published: April 2023

La crise énergétique et l’envolée des prix de l’électricité en Europe ont amené un certain nombre d’observateurs et de décideurs politiques à remettre en question le modèle de marché actuel fondé sur les coûts marginaux. Parmi les nombreuses propositions de réforme formulées, deux d’entre elles ont plus particulièrement retenu l’attention : 1) plafonner à court terme les prix du gaz utilisé pour la production d’électricité (option espagnole) ; ou 2) instaurer à moyen terme un modèle de marché dual combinant un ordre de mérite fondé sur les coûts marginaux pour les énergies fossiles à coûts variables élevés et des contrats de long terme basés sur les coûts moyens pour les producteurs bas-carbone à coûts fixes élevés (option grecque). Le débat se pose avec d’autant plus de vigueur que la hausse des coûts de l’énergie constitue le principal moteur de l’inflation en Europe, laquelle atteignait plus de 10 % sur un an en octobre 2022. Une situation qui pèse sur la compétitivité de la zone euro face à ses principaux partenaires commerciaux souvent moins sévèrement affectés par la crise énergétique.
Les secteurs électriques en marche vers un régime hybride combinant marché et planification
Authors: Finon Dominique
Published: April 2023

La résurgence de l’intervention publique dans le secteur électrique soulève la question de savoir comment adapter au mieux le market design pour relever le défi de l’investissement associé aux objectifs de sécurité de la fourniture et de décarbonation. L’évolution vers un régime de marché hybride semble inévitable, que ce soit en Europe ou aux États-Unis, dès lors que sont introduites hors marché des énergies renouvelables intermittentes et qui, du fait d’un coût marginal nul, faussent toutes les coordinations en place. Ce régime repose sur deux formes de régulation : d’une part, une planification s’articulant avec une concurrence « pour les marchés » destinée au développement de nouvelles capacités s’appuyant sur différentes techniques et, d’autre part, une concurrence « sur le marché » limitée à la réalisation du dispatching économique. La crise actuelle liée à l’augmentation des prix de l’électricité devrait accélérer cette mutation, en donnant un poids nouveau à la recherche d’un alignement des prix de vente sur les coûts de développement du système.
Être propriétaire au seuil de la retraite : une analyse des inégalités entre générations (1910-1954)
Authors: Le Roux Guillaume , Rochut Julie , Gallou Rémi , Bonvalet Catherine
Published: April 2023

Le patrimoine immobilier constitue une ressource essentielle au seuil de la retraite, au moment où les ménages abordent cette nouvelle étape du cycle de vie et peuvent envisager de nouveaux projets résidentiels ou une désépargne, en vendant un bien immobilier. Mais ces ressources immobilières sont détenues de façon très inégale selon les catégories sociales et les générations. L’objectif de cet article est de rendre compte des disparités du patrimoine immobilier des ménages vers l’âge de 60 ans, en s’intéressant à la possession de la résidence principale ainsi qu’à celle d’autres logements (résidence secondaire ou logement de rapport). À partir des enquêtes Logement de 1973 à 2013, nous dressons un panorama de ces inégalités au sein des générations nées entre 1910 et 1954, ainsi qu’entre elles, en resituant leurs parcours dans le contexte socio-économique dans lequel ils se sont déroulés, favorisant ou non l’achat de logements. Nous montrons que la diffusion de la propriété du logement au cours des cinquante dernières années ne s’est pas faite de manière uniforme selon les générations et les catégories sociales, les inégalités se cristallisant au seuil de la retraite. Les contextes économiques et les politiques du logement ont ainsi largement favorisé la constitution d’un patrimoine immobilier pour les générations 1935-1950, mais les inégalités se sont dans le même temps renforcées et amplifiées entre classes sociales en raison de la complexification des trajectoires familiales.
IMC-MDA: Prediction of miRNA-disease association based on induction matrix completion
Authors: Li Zejun , Zhang Yuxiang , Bai Yuting , Xie Xiaohui , Zeng Lijun
Published: April 2023

To comprehend the etiology and pathogenesis of many illnesses, it is essential to identify disease-associated microRNAs (miRNAs). However, there are a number of challenges with current computational approaches, such as the lack of "negative samples", that is, confirmed irrelevant miRNA-disease pairs, and the poor performance in terms of predicting miRNAs related with "isolated diseases", i.e. illnesses with no known associated miRNAs, which presents the need for novel computational methods. In this study, for the purpose of predicting the connection between disease and miRNA, an inductive matrix completion model was designed, referred to as IMC-MDA. In the model of IMC-MDA, for each miRNA-disease pair, the predicted marks are calculated by combining the known miRNA-disease connection with the integrated disease similarities and miRNA similarities. Based on LOOCV, IMC-MDA had an AUC of 0.8034, which shows better performance than previous methods. Furthermore, experiments have validated the prediction of disease-related miRNAs for three major human diseases: colon cancer, kidney cancer, and lung cancer.
Defining Business Objectives Supported by Organizational Maturity and Benefits Management
Authors: Gomes Jorge Vareda , Romão Mário José Batista
Published: April 2023

Organizations today need to provide better products and services. The issues they face require integrated approaches and effective management of their resources. Maturity models help integrate traditionally separate organizational functions, define process improvement goals and priorities, provide guidance for quality processes, and provide a benchmark for evaluating the current processes. The benefits management approach emerges as a complement to traditional management practices and proposes a continuous mapping of benefits, implementing and monitoring intermediate results. Based on a case study, it is shown how a set of business objectives can be obtained from the identification, structuring, and monitoring of business benefits, supported by information technology enablers and organizational transformations and by a certain level of maturity. The authors state that the focus of a successful investment is not only on the implementation of technology, but mainly on changes in organizational performance and business efficiency through process improvements and changes in the way of working.
Dispersion or Agglomeration
Authors: Liu Ziwei , Ding Yibing
Published: April 2023

The paper analyzes the agglomeration of China's OFDI across 35 industries in 43 countries from 2014 to 2019 to provide a characterization of China's international production system and its dynamic changes. It examines how digital service trade barriers and regulatory heterogeneity impact China's OFDI agglomeration. The paper finds that China's OFDI distribution shows a trend of agglomerating at the host country-industry level year by year, especially in capital-intensive and technology-intensive industries. Empirical results indicate that digital services trade barriers significantly hinder the agglomeration of China's OFDI. Digital service trade barriers negatively affect OFDI agglomeration in technology-intensive industries and positively affect it in labor-intensive industries. Deconstructing digital service trade barriers in different policy areas, the paper finds that the negative impact of infrastructure and connectivity and intellectual property rights is greater than that in electronic transactions, while the impact of barriers in the payment system is not significant.
Basic Study on the Effect of Water Sprinkling Curing Immediately after Demolding on the Initial Strength of Steam Cured Mortars
Authors: Sato Tsubasa , Katsuoka Nana , Uno Yoshiki , Date Shigeyuki
Published: April 2023

Steam curing is generally applied to improve productivity of precast concrete products. After steam curing, the products are stored outdoors as a secondary curing process until shipment. However, drying shrinkage and expansion of microcracks that occur during steam curing may inhibit strength improvement. On the other hand, water curing is also clearly effective as a secondary curing process. However, installing a water curing pool in a precast concrete plant is not easy due to limited space. Therefore, we focused on water sprinkling curing, which is relatively easy to perform without such restrictions. In this study, the effects of water sprinkling curing on the physical properties of mortar at the early age of steam curing were studied from the aspects of materials, mix proportions, curing conditions, and temperature of water used for sprinkling curing. As a result, it was confirmed that water sprinkling curing at an early age after demolding resulted in a rapid decrease in the temperature of the mortar surface layer. However, it was confirmed that the same conditions were effective in increasing compressive strength.
Distinctive Dynamics and Functions of the CD4+CD25+FOXP3+ Regulatory T Cell Population in Patients with Severe and Mild COVID-19
Authors: Nam Heejin , Koh June-Young , Jung Jae Hyung , Jeong Hyeongseok , Jeong Hye Won , Cheon Shinhye , Park Su-Hyung , Kim Yeon-Sook , Shin Eui-Cheol
Published: April 2023

Although CD4+CD25+FOXP3+ regulatory T (TREG) cells have been studied in patients with COVID-19, changes in the TREG cell population have not been longitudinally examined during the course of COVID-19. In this study, we longitudinally investigated the quantitative and qualitative changes in the TREG cell population in patients with COVID-19. We found that the frequencies of total TREG cells and CD45RA−FOXP3hi activated TREG cells were significantly increased 15–28 d postsymptom onset in severe patients, but not in mild patients. TREG cells from severe patients exhibited not only increased proliferation but also enhanced apoptosis, suggesting functional derangement of the TREG cell population during severe COVID-19. The suppressive functions of the TREG cell population did not differ between patients with severe versus mild COVID-19. The frequency of TREG cells inversely correlated with SARS-CoV-2–specific cytokine production by CD4+ T cells and their polyfunctionality in patients with mild disease, suggesting that TREG cells are major regulators of virus-specific CD4+ T cell responses during mild COVID-19. However, such correlations were not observed in patients with severe disease. Thus, in this study, we describe distinctive changes in the TREG cell population in patients with severe and mild COVID-19. Our study provides a deep understanding of host immune responses upon SARS-CoV-2 infection in regard to TREG cells.
Identification and Characterization of Alveolar and Recruited Lung Macrophages during Acute Lung Inflammation
Authors: Han Wei , Tanjore Harikrishna , Liu Yang , Hunt Raphael P , Gutor Sergey S , Serezani Ana P M , Blackwell Timothy S
Published: April 2023

To precisely identify mouse resident alveolar macrophages (AMs) and bone marrow (BM)–derived macrophages, we developed a technique to separately label AMs and BM-derived macrophages with a fluorescent lipophilic dye followed by FACS. We showed that this technique overcomes issues in cell identification related to dynamic shifts in cell surface markers that occurs during lung inflammation. We then used this approach to track macrophage subsets at different time points after intratracheal (i.t.) instillation of Escherichia coli LPS. By isolating BM-derived macrophages and AMs, we demonstrated that BM-derived macrophages were enriched in expression of genes in signal transduction and immune system activation pathways whereas resident AMs were enriched in cellular processes, such as lysosome/phagosome pathways, efferocytosis, and metabolic pathways related to fatty acids and peroxisomes. Taken together, these data indicate that more accurate identification of macrophage origin can result in improved understanding of differential phenotypes and functions between AMs and BM-derived macrophages in the lungs.
Mycobacterium tuberculosis–Induced Prostaglandin J2 and 15-Deoxy-Prostaglandin J2 Inhibit Inflammatory Signals in Human M1 Macrophages via a Negative Feedback Loop
Authors: Ning Yuping , Wang Wenfei , Jordan Paul M , Barth Stefanie A , Hofstetter Robert Klaus , Xu Jinjin , Zhang Ximeng , Cai Yi , Menge Christian , Chen Xinchun , Werz Oliver
Published: April 2023

Tuberculosis caused by Mycobacterium tuberculosis is a leading cause of death globally and a major health concern. In humans, macrophages are the first line invaded by M. tuberculosis. Upon infection, macrophages upregulate cyclooxygenase-2 (COX-2) expression and consequently elevate the formation of PGs, including PGE2 and PGD2. Although the role of proinflammatory PGE2 in M. tuberculosis infection has been reported, the roles of PGJ2 and 15-deoxy-PGJ2 (collectively named J2-PGs), the metabolites of PGD2 with anti-inflammatory features, remain elusive. In this study, we show that M. tuberculosis (H37Rv strain)–conditioned medium stimulates human monocyte-derived macrophages (MDMs) to elevate COX-2 expression along with robust generation of PGJ2, exceeding PGD2 formation, and to a minor extent also of 15-deoxy-PGJ2. Of interest, in M1-MDM phenotypes, PGJ2 and 15-deoxy-PGJ2 decreased M. tuberculosis (H37Rv strain)–conditioned medium–induced COX-2 expression and related PG formation by a negative feedback loop. Moreover, these J2-PGs downregulated the expression of the proinflammatory cytokines IL-6, IL-1β, and IFN-γ, but elevated the anti-inflammatory cytokine IL-10 and the M2 markers arginase-1 and CD163. These anti-inflammatory effects of J2-PGs in M1-MDM correlated with impaired activation of TGF-β–activated kinase 1/NF-κB/MAPK pathways. Finally, we found that J2-PGs regulate COX-2 expression, at least partially, via PGD2 receptor (DP1) and chemoattractant receptor homologue expressed on Th2 cells/DP2 receptors, but independent of the J2-PG receptor peroxisome proliferator-activated receptor-γ. Together, our findings reveal that M. tuberculosis induces COX-2 expression in human M1-MDMs, along with robust formation of J2-PGs that mediates anti-inflammatory effects via a negative feedback loop.
Primary Care Screening Tool for Polycystic Ovary Syndrome: Step One in the Battle Against Non-Communicable Disease
Authors: Kalra S , Vaidya R , Verma M , Joshi A
Published: April 2023

Polycystic ovary syndrome (PCOS) is often the first manifestation, in adolescents and young adults, of metabolic problems that may occur later. Early identification, timely referral and appropriate treatment can result in improved reproductive, metabolic and comprehensive health. However, unlike other components of metabolic syndrome, which can be diagnosed at primary care level, there is no inexpensive, clinical tool to screen for PCOS. We share a simple six-item questionnaire, structured in three domains, which can be used as a screening tool for the syndrome. This allows early diagnosis and management of the condition, facilitates a life course approach to health promotion, and lays the foundation for the prevention of other comorbid metabolic disorders. It also helps integrate national programmes concerning non-communicable disease and women’s healthcare under one umbrella, thus optimizing and strengthening delivery of community care.
The View from Here: A Woman Early Career Endocrinologist in India
Authors: Nagendra L
Published: April 2023

Being a young female endocrinologist and a new mother brings its own challenges. As much as an understanding family helped me deal with the myriad of things at home, equally understanding colleagues and the huge network of endocrine fraternity provided me the much-needed support professionally. From helping me juggle my responsibilities, to answering all my questions about complex endocrine disorders, the close-knit endocrine fraternity in India has been my greatest source of strength. I am sure my story and experiences will inspire many more women to be part of this wonderful fraternity.
L-carnitine-loaded nanoparticle ameliorates cypermethrin-induced reproductive toxicity in adult male rats
Authors: Alyasari Noora Kadhim Hadi , Selman Wisam Hussein
Published: April 2023

The objective of this investigation was to find out whether L-carnitine-loaded nanoparticle (LCn) could reduce the reproductive toxicity of cypermethrin (CYP), the widely used insecticide in veterinary medicine in male rats. Twenty male Wistar rats that weighed between 210 and 240 g were split into four groups and treated daily for 2 months. The control group was given 0.9% normal saline solution daily. The second group received CYP (3.83 mg/kg b. w. p. o.) daily. The third group was administered with LCn and CYP (50 mg/kg b. wt. p. o. and 3.83 mg/kg b. wt. p. o., respectively) daily, whereas the fourth group received LCn alone (50 mg/kg b. wt. p. o.) daily. On day 60, all rats were sacrificed and samples were collected. CYP-treated animals exhibited inhibition of testicular anti-oxidative stress mechanisms, testicular steroidogenesis enzyme activity (3β-hydroxysteroid dehydrogenase [3β-HSD] and 17β-HSD), and downregulation of steroidogenic acute regulatory (StAR) gene expression. In addition, it decreased testosterone, follicle-stimulating hormone, and LH levels and had detrimental consequences for sperm quality. LCn attenuated CYP-induced reproductive toxicity via the alleviation of testicular oxidative stress status, improvement of steroidogenic enzyme activity, and upregulation of StAR gene expression, which are probably responsible for the concomitant improvement in testicular hormonal levels and improvement in sperm properties. Intriguingly, LCn treatment alone could enhance the functions of the male reproductive system.