bluuebunny/crossref_metadata_2025 huggingface dataset:
Diversity and assembly processes of microbial eukaryotic communities in Fildes Peninsula Lakes (West Antarctica)
Authors: Zhang Chunmei , Li Huirong , Zeng Yinxin , Ding Haitao , Wang Bin , Li Yangjie , Ji Zhongqiang , Bi Yonghong , Luo Wei
Published: September 2022

Abstract. The diversity, co-occurrence patterns, and assembly processes of microbial
eukaryotes (0.2–20 µm) in Antarctic freshwater lakes are not well
understood, despite their wide distribution and ecological importance. This
study used Illumina high-throughput sequencing to investigate the microbial
eukaryotic communities of five freshwater lakes on the Fildes Peninsula over
three summer seasons. A total of 28 phyla were detected, with phytoplankton
occupying the highest percentage of sequences (accounting for up to 98 %).
The dominant taxa consisted of Chrysophyta, Chlorophyta, and Cryptophyta.
The species richness (113–268) and Shannon index (1.70–3.50) varied among
the lakes, with higher values recorded in Lake Chang Hu and Lake Kitec and
the lowest value obtained for Lake Yue Ya. There were significant
differences between the microbial eukaryotic communities of the lakes, with
spatial and temporal heterogeneity in the relative abundance of the
dominant taxa (P<0.05). Environmental variables explained about
39 % of the variation in community structures, with water temperature and
phosphate identified as the driving factors (P<0.05). Network
analysis revealed comprehensive co-occurrence relationships (positive
correlation 82 % vs. negative correlation 18 %). The neutral community
model revealed that neutral processes explained more than 55 % of the
community variation. Stochastic processes (e.g. homogenizing dispersal and
undominated processes) predominated in community assembly over the
deterministic processes. These findings demonstrate the diversity of the
microbial eukaryotic communities in the freshwater lakes of the Fildes
Peninsula and have important implications for understanding the community
assembly in these ecosystems.
Burned Area and Carbon Emissions Across Northwestern Boreal North America from 2001–2019
Authors: Potter Stefano , Cooperdock Sol , Veraverbeke Sander , Walker Xanthe , Mack Michelle C. , Goetz Scott J. , Baltzer Jennifer , Bourgeau-Chavez Laura , Burrell Arden , Dieleman Catherine , French Nancy , Hantson Stijn , Hoy Elizabeth E. , Jenkins Liza , Johnstone Jill F. , Kane Evan S. , Natali Susan M. , Randerson James T. , Turetsky Merritt R. , Whitman Ellen , Wiggins Elizabeth , Rogers Brendan M.
Published: September 2022

Abstract. Fire is the dominant disturbance agent in Alaskan and Canadian boreal ecosystems and releases large amounts of carbon into the atmosphere. Burned area and carbon emissions have been increasing with climate change, which have the potential to alter the carbon balance and shift the region from a historic sink to a source. It is therefore critically important to track the spatiotemporal changes in burned area and fire carbon emissions over time. Here we developed a new burned area detection algorithm between 2001–2019 across Alaska and Canada at 500 meters (m) resolution that utilizes finer-scale 30 m Landsat imagery to account for land cover unsuitable for burning. This method strictly balances omission and commission errors at 500 m to derive accurate landscape- and regional-scale burned area estimates. Using this new burned area product, we developed statistical models to predict burn depth and carbon combustion for the same period within the NASA Arctic-Boreal Vulnerability Experiment (ABoVE) core and extended domain. Statistical models were constrained using a database of field observations across the domain and were related to a variety of response variables including remotely-sensed indicators of fire severity, fire weather indices, local climate, soils, and topographic indicators. The burn depth and aboveground combustion models performed best, with poorer performance for belowground combustion. We estimate 2.37 million hectares (Mha) burned annually between 2001–2019 over the ABoVE domain (2.87 Mha across all of Alaska and Canada), emitting 79.3 +/- 27.96 (+/- 1 standard deviation) Teragrams of carbon (C) per year, with a mean combustion rate of 3.13 +/- 1.17 kilograms C m-2. Mean combustion and burn depth displayed a general gradient of higher severity in the northwestern portion of the domain to lower severity in the south and east. We also found larger fire years and later season burning were generally associated with greater mean combustion. Our estimates are generally consistent with previous efforts to quantify burned area, fire carbon emissions, and their drivers in regions within boreal North America; however, we generally estimate higher burned area and carbon emissions due to our use of Landsat imagery, greater availability of field observations, and improvements in modeling. The burned area and combustion data sets described here (the ABoVE Fire Emissions Database, or ABoVE-FED) can be used for local to continental-scale applications of boreal fire science.
The rate of information transfer as a measure of ocean-atmosphere interactions
Authors: Docquier David , Vannitsem Stéphane , Bellucci Alessio
Published: September 2022

Abstract. Exchanges of energy between the ocean and atmosphere are of large importance in regulating the climate system. Here we apply for the first time a relatively novel approach, the rate of information transfer, to quantify interactions between the ocean surface and lower atmosphere over the period 1988–2017 at monthly time scale. More specifically, we investigate dynamical dependencies between sea-surface temperature (SST), SST tendency and turbulent heat flux in satellite observations. We find a strong two-way influence between SST / SST tendency and turbulent heat flux in many regions of the world, with largest values in eastern tropical Pacific and Atlantic oceans, as well as in western boundary currents. The total number of regions with a significant influence of turbulent heat flux on SST and on SST tendency is reduced when considering the three variables, suggesting an overall stronger ocean influence compared to the atmosphere. We also find a relatively strong influence of turbulent heat flux taken one month before on SST. Additionally, an increase in the magnitude of the rate of information transfer and in the number of regions with significant influence is observed when looking at interannual and decadal time scales, compared to monthly time scale.
Resilience of UK crop yields to compound climate change
Authors: Slater Louise J. , Huntingford Chris , Pywell Richard F. , Redhead John W. , Kendon Elizabeth J.
Published: September 2022

Abstract. Recent extreme weather events have had severe impacts on
UK crop yields, and so there is concern that a greater frequency of extremes
could affect crop production in a changing climate. Here we investigate the
impacts of future climate change on wheat, the most widely grown cereal crop
globally, in a temperate country with currently favourable wheat-growing
conditions. Historically, following the plateau of UK wheat yields since the
1990s, we find there has been a recent significant increase in wheat yield
volatility, which is only partially explained by seasonal metrics of
temperature and precipitation across key wheat growth stages (foundation,
construction and production). We find climate impacts on wheat yields are
strongest in years with compound weather extremes across multiple growth
stages (e.g. frost and heavy rainfall). To assess how these conditions might
evolve in the future, we analyse the latest 2.2 km UK Climate Projections
(UKCP Local): on average, the foundation growth stage (broadly 1 October
to 9 April) is likely to become warmer and wetter, while the construction
(10 April to 10 June) and production (11 June to 26 July) stages are
likely to become warmer and slightly drier. Statistical wheat yield
projections, obtained by driving the regression model with UKCP Local
simulations of precipitation and temperature for the UK's three main
wheat-growing regions, indicate continued growth of crop yields in the
coming decades. Significantly warmer projected winter night temperatures
offset the negative impacts of increasing rainfall during the foundation
stage, while warmer day temperatures and drier conditions are generally
beneficial to yields in the production stage. This work suggests that on
average, at the regional scale, climate change is likely to have more
positive impacts on UK wheat yields than previously considered. Against this
background of positive change, however, our work illustrates that wheat
farming in the UK is likely to move outside of the climatic envelope that it
has previously experienced, increasing the risk of unseen weather conditions
such as intense local thunderstorms or prolonged droughts, which are beyond
the scope of this paper.
Streamflow data availability in Europe: a detailed dataset of interpolated flow-duration curves
Authors: Persiano Simone , Pugliese Alessio , Aloe Alberto , Skøien Jon Olav , Castellarin Attilio , Pistocchi Alberto
Published: September 2022

Abstract. For about 24 000 river basins across Europe, we provide a
continuous representation of the streamflow regime in terms of empirical
flow-duration curves (FDCs), which are key signatures of the hydrological behaviour of a catchment and are widely used for supporting decisions on
water resource management as well as for assessing hydrologic change. In this study, FDCs are estimated by means of the geostatistical procedure
termed total negative deviation top-kriging (TNDTK), starting from the empirical FDCs made available by the Joint Research Centre of the European Commission (DG-JRC) for about 3000 discharge measurement stations across
Europe. Consistent with previous studies, TNDTK is shown to provide high
accuracy for the entire study area, even with different degrees of reliability, which varies significantly over the study area. In order to
provide this kind of information site by site, together with the estimated FDCs, for each catchment we provide indicators of the accuracy and
reliability of the performed large-scale geostatistical prediction. The
dataset is freely available at the PANGAEA open-access library (Data Publisher for Earth & Environmental Science) at https://doi.org/10.1594/PANGAEA.938975
(Persiano et al., 2021b).
HMRFS–TP: long-term daily gap-free snow cover products over the Tibetan Plateau from 2002 to 2021 based on hidden Markov random field model
Authors: Huang Yan , Xu Jiahui , Xu Jingyi , Zhao Yelei , Yu Bailang , Liu Hongxing , Wang Shujie , Xu Wanjia , Wu Jianping , Zheng Zhaojun
Published: September 2022

Abstract. Snow cover plays an essential role in climate change and
the hydrological cycle of the Tibetan Plateau. The widely used Moderate
Resolution Imaging Spectroradiometer (MODIS) snow products have two major
issues: massive data gaps due to frequent clouds and relatively low estimate
accuracy of snow cover due to complex terrain in this region. Here we
generate long-term daily gap-free snow cover products over the Tibetan
Plateau at 500 m resolution by applying a hidden Markov random field (HMRF)
technique to the original MODIS snow products over the past two decades. The
data gaps of the original MODIS snow products were fully filled by optimally
integrating spectral, spatiotemporal, and environmental information within
HMRF framework. The snow cover estimate accuracy was greatly increased by
incorporating the spatiotemporal variations of solar radiation due to
surface topography and sun elevation angle as the environmental contextual
information in HMRF-based snow cover estimation. We evaluated our snow
products, and the accuracy is 98.29 % in comparison with in situ observations, and
91.36 % in comparison with high-resolution snow maps derived from Landsat
images. Our evaluation also suggests that the incorporation of
spatiotemporal solar radiation as the environmental contextual information
in HMRF modeling, instead of the simple use of surface elevation as the
environmental contextual information, results in the accuracy of the snow
products increases by 2.71 % and the omission error decreases by 3.59 %.
The accuracy of our snow products is especially improved during snow
transitional period, and over complex terrains with high elevation and
sunny slopes. The new products can provide long-term and spatiotemporally
continuous information of snow cover distribution, which is critical for
understanding the processes of snow accumulation and melting, analyzing its
impact on climate change, and facilitating water resource management in
Tibetan Plateau. This dataset can be freely accessed from the National
Tibetan Plateau Data Center at https://doi.org/10.11888/Cryos.tpdc.272204
(Huang and Xu, 2022).
Data-driven aeolian dust emission scheme for climate modelling, evaluated with EMAC 2.54
Authors: Klingmüller Klaus , Lelieveld Jos
Published: September 2022

Abstract. Aeolian dust has significant impacts on climate, public health, infrastructure and ecosystems. Assessing dust concentrations and these impacts is challenging because the emissions depend on many environmental factors and can vary greatly with meteorological conditions. We present a data-driven aeolian dust scheme that combines machine learning components and physical equations to predict atmospheric dust concentrations and quantify the sources. The numerical scheme was trained to reproduce dust aerosol optical depth retrievals by the Infrared Atmospheric Sounding Interferometer on board the MetOp-A satellite. The input parameters included meteorological variables from the fifth generation atmospheric reanalysis of the European Centre for Medium-Range Weather Forecasts. The trained dust scheme can be applied as an emission submodel, to be used in climate and Earth system models, which is reproducibly derived from observational data so that a priori assumptions and manual parameter tuning can be largely avoided. We compared the trained emission submodel to a state-of-the-art emission parametrisation, showing that it substantially improves the representation of aeolian dust in the global atmospheric chemistry-climate model EMAC.
A review of different mascon approaches for regional gravity field modelling since 1968
Authors: Antoni Markus
Published: September 2022

Abstract. The geodetic and geophysical literature shows an abundance of mascon approaches for modelling the gravity field of the Moon or Earth on global or regional scales. This article illustrates the differences and similarities between the methods, which are labelled as mascon approaches by their authors. Point mass mascons and planar disc mascons were developed for modelling the lunar gravity field from Doppler tracking data. These early models had to consider restrictions in observation geometry, computational resources or geographical pre-knowledge, which influenced the implementation.
Mascon approaches were later adapted and applied for the analysis of GRACE observations of the Earth's gravity field, with the most recent methods based on the simple layer potential. Differences among the methods relate to the geometry of the mascon patches and to the implementation of the gradient and potential for field analysis and synthesis. Most mascon approaches provide a direct link between observation and mascon parameters – usually the surface density or the mass of an element – while some methods serve as a post-processing tool of spherical harmonic solutions.
This article provides a historical overview of the different mascon approaches and sketches their properties from a theoretical perspective.
O controle jurisdicional de convencionalidade em matéria ambiental e sua aplicação na solução de litígios
Authors: Badr Eid , Mara Arruda de Sá e Brito Annie
Published: September 2022

The present paper aims to analyse if the jurisdictional control of conventionality is an effective measure and if its application is possible in dispute settlement regarding environmental matters in Brazilian legal framework, according to the current understanding of the Inter-American Human Rights System. Thus, it discussed the relevance of having internal norms whose validity (and effectiveness) are also compatible with the international framework, whose examination is made through control of conventionality, with primary responsibility falling to Brazilian judges and courts by force of competence attributed by the various internal normative sources and in accordance with the latest interpretation of the Inter-American Court in Advisory Opinion OC-23/17. One concludes that the contemporary global reality calls for norms that accompany scientific and technological advancement without neglecting protection to the environment and to human rights. Therefore, the environmental jurisdictional control of conventionality is a possible and necessary measure to be applied in dispute settlement, aiming not only to avoid a regression in environmental matters, but also to enable and advancement towards sustainable development. The employed methodology, regarding the means, used the deductive and descriptive method, through doctrine, jurisprudential and bibliographic analysis, seeking to reach the objectives of the research. As to the ends, the research approach was qualitative.
A jurisdição constitucional brasileira entre direito e política: judicializando a política na busca por uma moral corretiva
Authors: Hoffmam Fernando , Andrade Obaldia Bruna
Published: September 2022

The article pretends to investigate to what extent the judicial decisions within the sphere of Brazilian constitutional jurisdiction communicate with the policy, mainly with a view to the phenomenon of the judicialization of policy in the search was a corrective moral. Thus, the essay begins by investigating the relationship between law and policy, going through the study of judicial activism – notably to the need for a corrective moral of/in law – and, finally, it arrives in the investigation of the Brazilian constitutional jurisdiction inserted in the scenario approached by the previous chapters, showing votes in recent decisions in the STF that corroborate the ideas raised during the research. In the end, it was possible to understand that the activist judicial posture can be understood as an absolutely arbitrary action by the interpreter, linked to politics, – because it is based on an idea of corrective moral – making the constitutional judicial decisions closely linked to the political agendas that end up disfiguring the law.
The function of competencies in the Australian nursing sector: A critical exploration
Authors:   , Ardern Rachel
Published: September 2022

By the end of the 20th century, hospital-based nurse training was replaced by nursing university programs with a greater focus on theoretically informed practice. This move coincided with the appearance of the competency movement across industries. Nursing competencies were primarily associated with political interests of increasing the flexibility through the demonstration of generic skills that could effectively increased scopes of practice. This flexibility created a blurring between RNs/ENs that contributed to an environment where neither role had clearly defined disciplinary boundaries. Competencies provided financial rewards for the organisation while increasing the workload of ENs and limiting the functions of RNs.
Formação da educador(a) dialógica numa perspectiva decolonializante
Authors: B. A. Figueiredo João
Published: September 2022

Texto resultante do pós-doutorado do autor.
A Rare Case: Genital Warts in Pregnancy
Authors: Bharti Sapna , Sugha Varuna
Published: September 2022

Genital wart is a benign lesion which is caused by Human Papillomavirus (HPV) type-6 or type-11 infection. Liu et al. found an overall HPV prevalence of 16.82% in pregnant women vs. 12.25% in non-pregnant women [1]. The persistence of HPV is arguably favored as the maternal hormonal environment and immune system undergo significant changes during pregnancy.[2] Here, we report an interesting case of 30 year old primigravida with vaginal warty growth.

Keywords: human papillomavirus, genital warts, pregnancy, trichloroacetic acid
Case Report on Self-Prescribed Abortion Pill Intake: A Downhill to Maternal Morbidity
Authors: Bharti Sapna , Sugha Varuna
Published: September 2022

The mortality is more common in the countries where the abortion is not legalized. Unsafe abortions cause 8–11% of global maternal deaths and occur predominantly in low-income and middle-income countries.[1] Medical Termination of Pregnancy (MTP Act) was passed in 1971 by Indian Parliament, with the goal to regulate and ensure accessibility for safe abortion. After the passage of this Act, legal position was given to abortion in India.[2] This act defined when, where and by whom it can be done. World Health Organization (WHO) and Federation of Obstetrician and Gynecologist Societies of India (FOGSI) have formulated guidelines for pre-abortion work up and examination for confirmation of pregnancy, correct gestational age and confirm the intra-uterine location of the pregnancy.[3] Despite liberal abortion care services provided in India, many women tend to self-medicate with abortion pills for MTP. This in turn results in high rate of unsupervised abortions and life-threatening complications. We are hereby presenting a case report on 28 year old P1+1 with history of OTC abortion pill intake at approximately 9 week with excessive bleeding per vaginum with endometritis with previous LSCS.

Keywords: Abortion, self-prescribed abortion pill, OTC abortion pill, MTP, Medical Termination of PregnancyAbortion, self-prescribed abortion pill, OTC abortion pill, MTP, Medical Termination of Pregnancy
Repeated Doctor Shopping in Functional Abdominal Pain Patient and Its Impact: A Case Report
Authors: Bharti Sapna , Sugha Varuna
Published: September 2022

Doctor-shopping involves visiting multiple doctors with the same health problem and is often observed in outpatient clinics.[1] Patients visit more doctors when they have a chronic disease or a drug addiction and their health problem remains unresolved despite receiving treatment.[2] The provider-patient relationship is essential to treatment of patient. If patient is visiting multiple doctors at same time without any previous records and even not disclosing previous checkups leads to repeated prescription of medication, increased drug dose consumption and increased healthcare cost as well. Here we report a case of 54 year female with chronic functional abdominal pain with once to twice weekly checkups at different hospital and with different specialist consultations.

Keywords: doctor shopping, healthcare cost, drug abuse
Prevalence of Overweight and Obesity in School Children Aged 5-12 Years of Kottayam, India
Authors: Paulose Amrtha , Aluckal Eby
Published: September 2022

Introduction: Childhood obesity represents a major health problem with potentially devastating consequences and has increased worldwide rapidly in the past two decades. An early detection of overweight and obesity, and lifestyle modifications for its prevention is important.
Aim: The aim of the study was to estimate the prevalence and risk factors of overweight and obesity in school children aged 5-12 years of Kottayam, India.
Methods: 1200 children of both sexes were studied from three private schools and two government schools belonging to the age group of 5-12 years using Cluster sampling technique. A structured questionnaire to elicit the socio-demographic variables, family history, dietetic habits and physical activities were given. Children are also subjected to General physical examination, blood pressure recording and Anthropometric examination. The body mass index in units of kg/m2 was determined and children were categorized according to age and gender specific criteria as underweight (<5th percentile), normal (5th -85th percentile), overweight (85th – 95th percentile) and obese (>95th percentile). The data were subjected to statistical analysis using appropriate statistical tests.
Results and Conclusions: The proportion of subjects in CDC weight categories were 18% underweight, 72% normal, 7% overweight and 3% obese. Overweight and obesity is significantly related to age, sex, birth weight, physical inactivity and economic status. This study also shows that obesity is unevenly distributed in the community.

Keywords: Anthropometric, body mass index; inactivity; obesity; overweight
Deep Transfer Learning Approach for Identification of Daily Living Human Activities
Authors: Nurfarida Kristina
Published: September 2022

Deep learning is one of the of AI methods where there are number of layers of information which are addressed as neurons and assists with understanding the information proficiently. AI helps the machines and frameworks to comprehend the human activities themselves and afterward answer in a manner that is controlled effectively toward the end client of that specific application, framework and so forth. Various deep learning calculations are utilized to execute the idea where the profound gaining begins the interaction by taking information from one layer and give it to the following layer of information. A great deal of data and information is put away as layers and order where they are associated with one another by organization of neurons which go about as data of interest for each layer. Transfer learning is the new concept in deep learning where the data and information is transferred from one model to other model and thus it saves time and resources and cost of utilising it. Deep transfer learning contributes to get results in different model by using already existing model or by utilising few components of already existing model. There are many profound learning systems which are utilized across different spaces to simple and work on the errand of the business. The paper will explain the types of deep transfer learning methods, its benefits as well as challenges to implement the concept. It is widely used to identify daily human activities.
Conceptual Analysis and Intellectual History
Authors: Koronaj Drača Vinko , Malatesti Luca
Published: September 2022

We investigate whether the analysis of the concept of mental disorder, as carried out in analytic philosophy of psychiatry, can contribute significantly to the intellectual history of antisocial personality disorders. We discuss and address possible pitfalls of this interdisciplinary interaction. Using insights from analytic philosophy of psychiatry, we investigate whether there were significant differences in the explicit conceptualisation of the notion of harm in diagnoses of moral insanity in relevant texts of Austrian and Croatian psychiatrists at the turn of the 19th and 20th century. Our finding that different notions of harm were at the core of debates on moral insanity in early Croatian psychiatry indicates the fruitfulness of the interaction between analytic philosophy and intellectual history of psychiatry.
Extension and Validation of NEMA-Style Dual-Ring Controller in SUMO
Authors: Schrader Max , Wang Qichao , Bittle Joshua
Published: September 2022

Until recently, SUMO users could not model the behavior of a ring-and-barrier traffic signal via existing signal types, which left North American SUMO users without the direct ability to capture traffic dynamics of their local networks. This work presents the methods, implementation overview, and validation of a ‘dual-ring’ NEMA style traffic controller which has recently been added to the main SUMO code base. A brief explanation of the ‘dual-ring’ implementation is also provided as context for those new to this type of traffic controller. The foundation for this work was presented at the SUMO User Conference 2021 by researchers at the US Department of Energy’s National Renewable Energy Laboratory, but was not integrated into SUMO code base at the time. Following the initial inclusion of the controller to SUMO, the authors began validation of the SUMO controller against an Econolite software-in-the-loop (SIL) traffic signal controller configured with actual setup parameters from controllers in a real-world three-intersection corridor in Tuscaloosa, Alabama, USA. This paper documents the process of adding new features to the controller code as well as validating their implementation through simulation-based and automated grey-box testing is presented in this paper. Key features such as fully-actuated operation, various timing offset plans, proper next-phase fit algorithms and more, have been added and validated against this SIL system. Though not an exhaustive demonstration of features, this work is intended make more users aware of this extension of SUMO capabilities.
Amanecer agustiniano por las Islas de Poniente. Los agustinos abanderados de la Misión en el s. XVI
Authors: Álvarez Fernández Jesús
Published: September 2022

Fueron los agustinos los pioneros de la Evangelización en Filipinas. Y Urdaneta quien proporcionó el billete de ida y vuelta, el Tornaviaje. Reflexionamos en este ensayo sobre su organización comunitaria, su vida cotidiana, su inculturación, su labor evangelizadora y social y su lucha por la justicia.
Octavo libro de profesiones del convento San Agustín de Zaragoza (1799-1834)
Authors: Lazcano González Rafael
Published: September 2022

Los libros de profesiones religiosas son una fuente documental de primer orden para el conocimiento de las características  humanas, culturales y sociales de los miembros de una provincia religiosa. A lo largo de siete trabajos consecutivos se presentará cada uno de los libros de profesiones que se conservan del convento San Agustín de Zaragoza (1605-1834; excepto el libro séptimo, 1730-1799, por encontrarse extraviado) y los datos básicos de los profesantes: nombre (s) y apellidos, cómo se llamaban sus padres, lugar de origen o nacimiento, parroquia de bautismo, fecha de profesión religiosa, nombre del prior (o subprior) de la casa y del prior general de la Orden de San Agustín, quién fue el maestro de novicios, e incluso el notario que daba fe del hecho de la profesión. A su vez, las actas de profesión ofrecen otros pormenores de no menor importancia para el multifacético quehacer del historiador. Este artículo trata del octavo y último libro de profesiones del convento San Agustín de Zaragoza (1799-1834).
Cuerpos lipídicos y estrés oxidante
Authors: Serrano García Norma , Orozco Ibarra Marisol
Published: September 2022

Oxidative stress is a characteristic of cell damage in various diseases since one of its primary effects is lipid peroxidation, with the consequent generation of toxic aldehydes and ketones. For their part, lipid droplets are ubiquitous and highly conserved cellular organelles responsible for storing neutral lipids. The functional relevance of lipid storage depends on the physiological state and cell type since it has been shown that the formation of

lipid droplets depends on factors such as nutritional status or cellular stress. Although lipid droplets are predominantly located in adipose tissue, they are also found in many other tissues, such as nervous, cardiac, and hepatic, where they fulfill various functions. In this work, we present evidence of the relationship that has been found between oxidative stress and the function of lipid droplets.
La expresión de 8-hidroxi 2’-desoxiguanosina en el cáncer
Authors: Caballero Sánchez María Dolores , Hernández Cruz Pedro Antonio , Hernández Juárez Jesús , Fernández Rojas Berenice
Published: September 2022

The production of reactive oxygen species

(ROS) takes place in all organisms. ROS regulate the cell

cycle and other biological phenomena that make them

essential for life. However, when there is a ROS excess

and/or the antioxidant system is reduced, oxidative stress

is induced. During this process, ROS can attack various

biomolecules and generate oxidative damage. The hydroxyl

radical is a highly reactive ROS that can react with guanine

in deoxyribonucleic acid (DNA), generating the molecule

8-hydroxy-2’-deoxyguanosine (8-OHdG), a marker of

oxidative damage to DNA. Some research have shown that

cancer patients or mouse models of cancer have elevated

levels of 8-OHdG in serum, urine, saliva, and tissues. This

literature review summarizes the main findings of 8-OHdG

in several types of cancer and shows the evidence for the

potential use of 8-OHdG as a biomarker of oxidative DNA

damage in cancer.
FAILURE ANALYSES OF TOWER CRANE USING FEM AND THEORETICAL STUDIES
Authors: Ghazwani Mofareh Hassan , Alnujaie A. H. , Chandravanshi M. L. , Deepak Deepak , Singh Chitransh , Kumar Mrityunjay
Published: September 2022

This paper describes the technique to explicitly increase the tower crane’s stability during cyclones through modal analysis in FEM. For this, modal analyses of a boom, mast, and tower crane are carried out individually to minimize the tuning effect of natural frequencies. The study explains the methodology to increase the stiffness using bracings in the mast expressed in modal parameters. In FEM analysis, bracings are applied in fixed support along the vertical mast of the tower crane. For this purpose, a 1/10 scale model of “Potain MCi85 A/B” tower crane was modelled in Nx-Unigraphics. Theoretical analysis of the boom’s natural frequencies and its counterweight is assumed as cantilever beam and mast in form column. The values of natural frequencies of tower cranes under different boundary conditions are obtained through Galerkin and Dunkerley’s mathematical expressions. Theoretical and FEM results established similar trends of increasing stability as revealed in terms of natural frequencies of the tower crane.
Antenatal adrenal neuroblastoma revealed by subcutaneous nodules
Authors: El Houssni Jihane , Soukayna Jabour , El Haddad Siham , Chaimae Abourak , Abdellah Bassel Saber , Mehdi Tantaoui , Chat Latifa , Allali Nazik
Published: September 2022

Introduction: Neuroblastoma is the third most common malignancy in pediatrics, subcutaneous metastases of antenatal neuroblastoma are described in the literature and they represent 1% of secondary localizations of neuroblastoma.

Case Report: We report the case of a 12-month-old male infant with an antenatal neuroblastoma of the left adrenal gland revealed by inguino-scrotal and forearm subcutaneous nodules whose anatomopathological study was in favor of cutaneous metastases of a neuroblastoma.

Conclusion: Neuroblastoma is a very frequent embryonic tumor in pediatrics, subcutaneous metastases are often revealing of antenatal neuroblastoma, the diagnosis of certainty is essentially based on anatomopathological study.
Singularities and characteristics of Tafsir Tabseer ur Eahman wa Tayseer ul Manan
Authors: Bano Saeeda , Bano Dr. Najma
Published: September 2022

This Tafseer is a great and inspiring treasure to experience the Glorious Quran as an enthralling narrative. It captivates and sooths touches heart and motivates y to act righteously. One can understand how the different themes and stories in Quran give a comprehensive and complete world view. This is done by studying the context of revelation, Makkan and Madani suras, asbab an nuzul . It is Insightful, relevant commentary that helps to apply the Quran to everyday life, by carefully examining meanings of Arabic words and phrases, literary forms and style. To highlight the action points, questions, praise points, repentance points, and challenges of the Quran that will help a person to gain a deeper understanding of the Quran. That will enhance moral character, nuggets of wisdom that will improve social relations and spiritual ideals that will bring closer to Allah
Analytical Study of the Socio- Religious Condition of Early Ancient Egyptian Civilization
Authors: Akhter Dr. Naseem
Published: September 2022

This paper is primarily deals and highlights the main characteristics of the Egyptian civilization which is considered the mother civilizations of the world. The world has been making progress for thousands of years and the people became gradually civilized. We found few major civilizations of the world. Among them Egyptian Civilization is one of them which considered the most historic and early civilization as compared to its contemporary civilizations i.e. Mesopotamian, Indus and Chinese civilizations of the world. Although it’s a common perception about the people of ancient time that they were savages and had no sense of life. But when we observe them they looked very elegant people who introduced the different socio-political concepts regarding way of life, education, living, philosophy, socio-cultural norms along with religious traditions and political thoughts. In this context we look the ancient Egyptian civilization as cradle of civilizations of the world which consequently given a birth to other civilizations. It was the influence of this civilization which created the opportunities of trade, harmony and mutual cooperation among the people. This research paper is an attempt to explore the prominent feature of the ancient Egyptian civilization and how this civilization nourished.
Rastreio do câncer de mama e indicadores socioeconômicos no Brasil
Authors: Santos Barbara Rhayane , Aguiar João Eduardo Andrade Tavares de , Lira Juliana Maria Chianca , Silva Thais Serafim , Dias Júlia Maria Gonçalves
Published: September 2022

O câncer de mama (CM) é a principal causa de morte por câncer entre mulheres no Brasil, devido ao diagnóstico tardio. Sendo as principais causas o déficit no rastreio e no acesso ao serviço de saúde. Partindo desse pressuposto, este artigo tem como objetivo avaliar o rastreio do câncer de mama no Brasil, e a correlação com os indicadores socioeconômicos. Trata-se de uma revisão bibliográfica narrativa, o levantamento das publicações científicas foi realizado nas bases de dados: Lilacs, PubMed, Medline e SciELO. Através das pesquisas, verifica-se que o rastreio do CM está muito aquém das metas preconizadas, e sua cobertura ocorre de maneira heterogênea entre as macrorregiões do país. A correlação entre o rastreio e os indicadores socioeconômicos, não possui evidência suficiente, provavelmente, devido aos números pouco expressivos de exames realizados e as limitações dos indicadores, em contraponto com a realidade. Por fim, faz-se necessário que mais estudos sejam realizados a fim de ter melhores evidências quanto ao impacto do rastreio e dos indicadores, na vida das mulheres.
Caracterização molecular de etnovariedades de Manihot esculenta Crantz com utilização de marcadores moleculares ISSR
Authors: Cuchi Giovana , Cardoso Elisa dos Santos , Pedri Eliane Cristina Moreno de , Tiago Auana Vicente , Zortéa Kelli Évelin Müller , Rossi Ana Aparecida Bandini
Published: September 2022

A mandioca (Manihot esculenta) é amplamente distribuída no Brasil, nas roças encontram-se plantas com características diferentes que são mantidas e propagadas entre os agricultores. Levando em consideração a diversidade de etnovariedades encontrada, esse trabalho teve como objetivo realizar a caracterização molecular de etnovariedades de mandioca cultivadas no município de Paranaíta - MT, utilizando primers ISSR. O material foliar foi coletado em oito propriedades de Paranaíta. A extração de DNA foi realizada por meio do método CTAB e as amostras amplificadas via PCR. Foram utilizados 14 primers ISSR que após análise estatística foram classificados como moderadamente informativos. A comparação entre as informações cedidas pelos produtores e as distâncias genéticas entre as etnovariedades, permite inferir que a diversidade entre as mesmas está relacionada a história evolutiva da espécie. Os métodos de agrupamento utilizados indicam que dentre as etnovariedades analisadas, duas apresentaram potencial para estudos futuros por serem mais distantes geneticamente entre as demais.
Auditoria farmacêutica e seu papel no Sistema Único de Saúde
Authors: Melo Danielle Brandão de , Tosta-Leal Marcos Maurício , Santos Francisco José Pacheco dos
Published: September 2022

A Auditoria Farmacêutica (AF) é o exame sistemático e imparcial, de uma atividade, elemento ou sistema, para verificar a adequação aos requisitos preconizados pelas leis e normas vigentes. O objetivo deste artigo foi abordar a Auditoria Farmacêutica e seu papel no SUS. Configura uma revisão sistemática da literatura baseada em arquivos como das bases SciElo e LILACS, datados do período de 2000 a 2022, nos idiomas inglês, português ou espanhol. Na auditoria em saúde são analisados aspectos, como: valor de mercado, aplicabilidade do item, necessidade, custo-benefício, tipo de fornecedor, viabilidade do período a ser atendido com a quantidade do insumo adquirida, etc., visando intervir no processo, quando necessário, em prol de melhorias. No caso da AF, é imprescindível a competência do auditor em planejar e gerenciar o ciclo da assistência farmacêutica, tarefa restrita do farmacêutico. Conclui-se que o farmacêutico é o profissional mais indicado para realizar AF, por ser imprescindível uma prática eficiente da assistência farmacêutica, que ultrapassa o seu ciclo, compreendendo todas as atividades inerentes ao farmacêutico, profissional do cuidado conhecedor do medicamento, o insumo mais caro em saúde.
Haplogroups determination from RNR1 and RNR2 regions of mitochondrial DNA
Authors: Ariffin Shahrul Hisham Zainal , Din Rus Dina Rus , Wahab Rohaya Megat Abdul , Zahari Siti Nur Zahidah , Nazman Hanis Nabilah Mohd , Abidin Intan Zarina Zainol
Published: September 2022

Mitochondrial DNA (mtDNA) has two regions, i.e. coding and control regions which are also known as hypervariation (HV) regions. Analysis of hypervariation regions or the entire human mtDNA genome is an important element that could be used during human evolutionary, forensic or phylogenetic studies. Although most human phylogenetics studies often use HV regions; the lack of information from those regions can complicate the process of haplogroup determination. Therefore, in this study, the human mtDNA coding regions such as MT-RNR1 and MT-RNR2 genes were used as an alternative to determine the haplogroups. A total of four primer pairs were designed based on MT-RNR1 and MT-RNR2 genes using the Primer Designing Tool software. The human mtDNA sequence from the National Center for Biotechnology Information (NCBI) database (accession number NC_012920.1) was used as a reference. These primers were used in the PCR amplification approach using DNA genomic samples isolated from human peripheral blood. Polymorphism analysis of MT-RNR1 and MT-RNR2 regions using the Mitomaster database was performed to determine haplogroups. The results indicated that three haplogroups were identified which are N11a, H2a and H1. In conclusion, the primers designed from mitochondrial RNR1 and RNR2 genes can be used for human haplogroup identification.
Predictive values of first trimester ultrasound screening for twin-to-twin transfusion syndrome and selective intrauterine growth restriction in monochorionic twin pregnancies
Authors: El-Gaber Ali Abd El-Nasar Abd , Mohamed Mostafa Hussein , Khodary Mostafa Mohamed , Mohamed Altayeb Abd-alal Mostafa
Published: September 2022

Background: Monochorionic diamniotic (MCDA) twins are at significantly increased risk of perinatal morbidity and mortality due to shared placentation and the presence of inter-twin placental vascular anastomoses. Aim of the work: The main aim of this study was to validate first trimester ultrasound screening for twin-to-twin transfusion syndrome (TTTS) and selective intrauterine growth restriction (sIUGR) in monochorionic twin pregnancies using the triad of nuchal translucency (NT), cord insertion site and inter-twin discordance in fetal size. Summary: We have demonstrated that NT and CRL were significantly higher in TTTS group than sIUGR group. And difference in NT, CRL and cord insertion site was identified as predictive markers for sIUGR and TTTS.
Las ideas constantes en las Leyes de Indias.
Authors: Grenni Héctor
Published: September 2022

El autor presenta aquí un panorama de las ideas que se han mantenido en forma constante en los tres siglos de aplicación del Derecho Indiano en las colonias españolas de América. El presente escrito se detiene en la cuestión del lugar que debían ocupar los indios en el sistema social; por lo tanto, cuestiones como la dignidad de los indios y la idea de justicia en el sistema colonial merecen aquí un espacio importante. El escrito se detiene también en la cuestión de la encomienda, como constitución social colonial, porque en torno al debate que se suscitó a su alrededor se jugó buena parte del rumbo que tomó el Derecho Indiano.
Ética
Authors: Fúnez Rubén
Published: September 2022

En la presentación que vamos a hacer de la Ética de Sánchez Vásquez vamos a fijarnos en algunas ideas que consideramos fundamentales en dicha obra. La primera inquietud aborda y que consideramos de gran importancia en nuestro contexto, sobre todo por el uso indiscriminado que hacemos de ello, es la distinción entre moral y ética.
La paz y la justicia en el Documento de Medellín
Authors: Grenni Héctor
Published: September 2022

El presente artículo se detiene en el análisis de dos ideas que el autor considera de fundamental importancia en el Documento de Medellín: las ideas de paz y de justicia. Corresponden a los apartados 1 y 2 del Documento, que llevan, precisamente, esos nombres. El escrito hace hincapié en dos ideas que considera fundamentales: la de que la paz es, ante todo, obra de la justicia, y por lo tanto, no podrá existir la primera sin la existencia previa de la segunda; y la idea de que la paz es una construcción permanente. El Documento de Medellín estableció una íntima unión entre ambas como condición necesaria para una vida social humana.
Fiestas sin invitados
Authors: Gutiérrez Julio
Published: September 2022

Fiestas sin invitados, No. 33, julio-diciembre 2018
INVARIANCE: AN ANALOGY BETWEEN SYMMETRY AND CONSERVATION LAWS
Authors: Biswas Md. Haider Ali
Published: September 2022

Invariance plays an essential role in Physics and Mathematics. It has a close connection between symmetry and conserved quantity. In general any symmetry of the Lagrangian as well as Hamiltonian corresponds to a conserved quantity, and vice versa. This elegant works were first discussed and formalized by Emmy Neother. In this study an analogy is shown between invariance, symmetry and conservation laws.
EVALUATING SOILS FERTILITY OF TEA GARDENS OF NORTH EAST BANGLADESH
Authors: Billah Sk. M. , S.M Ullah, , A Begum.
Published: September 2022

Soils from tea garden in Sylhet and Moulovibazar, North East Bangladesh were analyzed for texture, organic matter, loss of moisture, pH, N, C/N ratio, Na, K, Ca, Mg, S, Fe, and Al. The soils are loamy to sandy loam, extremely acidic to acidic. They were very low in organic matter (0.87-1.60%), nitrogen content (0.051-0.121%) and pH (3.75-4.90). The exchangeable bases – Ca, Mg, Na and K - are also very low due to their leaching under existing acidic conditions. The C/N ratio is very low. The studied soils contain higher concentration of Fe, Al, and S. These soils are not ideal for tea cultivation because of low pH, organic matter, nitrogen, Na, Ca, Mg, and K contents. The data were statistically analyzed by LSD at 5% level of significance.