bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH KEGIATAN PAPER QUILLING TERHADAP PERKEMBANGAN MOTORIK HALUS ANAK
Authors: Ibrahim Nur Icca , Elvira Melly
Published: August 2024

This study aims to determine the development of children's fine motor skills. The implementation of the study was motivated by the problem of fine motor development of group A children at Insan Madani Plus Kindergarten, Malang City, which is still not optimal. This study used a Quassy experimental research design with One-Group Pretest-Posttest Design. The research was conducted at Insan Madani Plus Kindergarten Malang City in March 2023. The sample in this study were all children in group A of TK Plus Insan Madani Malang City, totaling 7 children. Data collection techniques using observation, for data analysis using the Wilcoxon Test.Based on the results of the study, using Pre-Test (before treatment) and Post-Test (after treatment) and data analysis conducted using the Wilcoxon test obtained a Z value of -2.379 and Asymp. Sig. (2-tailed) of 0.017, it can be concluded that there is a significant difference between posttest and pretest. The assumption in the Wilcoxon test is that if the Asymp.Sig value is <0.05, then the alternative hypothesis (Ha) is accepted, whereas if the Asymp.Sig value is >0.05, then Ha is rejected. In this case, since the Asymp.Sig value (0.017) < 0.05, Ha is accepted which indicates that there is a significant difference between the posttest and pretest. Therefore, it can be concluded that paper quilling activities have a significant effect on the fine motor development of children aged 4-5 years in group A of TK Plus Insan Madani Malang City.
STRATEGI GURU DALAM MENGAJARKAN MEMBACA PERMULAAN ANAK USIA 4-5 TAHUN
Authors: Lestari Dyah Ayu
Published: August 2024

The teaching process requires strategies so that learning activities become easier, more comfortable and get the intended results. The purpose of this study is to find out more about the stages of the strategies used by teachers in teaching children aged 4-5 years in the Jami' Grand Mosque Kindergarten in Malang and also the results of the strategies used. This research uses a qualitative approach and type of case study research because this research will further analyze how the strategies used by teachers in teaching beginning reading to children aged 4-5 years, namely group A in three classes. the instrument of this research is the researcher himself, with data collection techniques using interviews, observation notes, and documentation. The data analysis process refers to Miles and Huberman, namely by reducing data, presenting data and drawing conclusions. The results showed that the strategies used by teachers in teaching beginning reading to 4-5 year old children included direct learning strategies, individualized learning strategies, and group learning strategies. While the results of the strategies that have been applied make most of the group A children aged 4-5 years have the ability to read beginning. This can be seen from the characteristics that appear according to the standards of child development achievement.
Meningkatkan Minat Mencuci Tangan Pada Anak Usia 3-4 Tahun Menggunakan Jalur Berpola
Authors: Chusna Nazilatul
Published: August 2024

This study aims to determine the increase in interest in washing hands using patterned paths in children aged 3-4 years. By taking research subjects, namely 7 children with an age classification of 3-4 years at PAUD Griya Ananda Karangploso. This research uses a quantitative method with an exploratory descriptive approach, because the results of this research will be analyzed descriptively and by displaying calculated tables or graphs. The data collection technique used is in the form of a checklist sheet and documentation, as well as the data analysis technique used is using a proportional formula to convert the increase in children's interest.Based on the results of research carried out by researchers, it was concluded that the interest in washing hands of children in this study was in the low category, most children aged 3-4 years received low scores. Hand washing activities in playgroup classes were carried out every day with the help of class A or class B, which causes no own initiative to wash your hands when the time comes. This makes researchers use play media as a tool to increase interest in hand washing in playgroup classes. However, after being given play media, namely patterned paths, there was an increase in interest in washing hands using patterned paths for each child which can be seen in the research results. The research results showed that most children experienced an increase from the BB (Not Developing) category on the first day and then experienced an increase to the BSB (very well developed) category. It can be concluded that the use of play media, namely patterned paths, can make it easier for children to get to the hand washing place, is an effective method, is a safe media to use, and is easy for children to use to increase interest in washing hands in children aged 3-4 years.
Key considerations: Mpox, mining, and vulnerabilities of women and children in eastern DRC
Authors: Bashwira Marie-Rose , Mihigo Isidore Murhi , Duclos Diane
Published: August 2024

This brief presents considerations for contextualising and responding to the mpox outbreak in the mining towns of South Kivu province in the Democratic Republic of the Congo (DRC). The brief focuses on women and children living and working in artisanal and small-scale mining (ASM) areas. In South Kivu, in eastern DRC, most documented mpox cases have been in women (including women who engage in transactional sex) and children under the age of 15, including newborns. This brief highlights relevant socio-political contexts related to ASM, livelihoods, population mobility, and conflict and public health interventions. It discusses considerations for mpox vulnerabilities and access to healthcare for women and children. This brief draws on a SSHAP roundtable discussion on mpox in the DRC held in May 2024; conversations with experts and health actors active and/or knowledgeable in the region and outbreak; the authors’ own expertise on women’s and children’s lives in ASM areas in South Kivu; and academic and grey literature.
Evaluation of YouTube as an Information Source for Use of Laser in Root Canal Treatment
Authors: Tok Sevda , Ayranci Leyla
Published: August 2024

Objective: At the present time patients in developed countries widely use online resources to access medical information. YouTube is a widely used website to get knowledge. In the past, medical and dental data were accessed only by doctor and dentist examinations. This research was aimed to assess the quality and quantity of the knowledge content in popular YouTube™ videos about laser root canal treatment (LRCT).
Method: Google Trends showed that "laser root canal treatment" was the most searched keyword on the topic. Included videos were assessed as the video's name, universal resource locators, the number of video display, time of adding in website, total numbers of likes, dislikes and comments and total video time. Each video was classed into the 3 groups according to their information source as dentist, commercial, dental clinic. This video was classified according to the quality of information content as ‘good’, ‘poor’, or ‘bad’. In the evaluation of the data, the distribution of variables was examined with the Shapiro-Wilk normality test, the intergroup comparison of variables that did not show a normal distribution was examined with the Kruskal Wallis test. Comparison of subgroups was examined with Dunn's multiple comparison test and comparison of qualitative data was analyzed with Chi-square test. The results were evaluated at the significance level of p
African Migrant Learners’ Experiences of Xenophobia in South Africa
Authors: Nnadozie Jude Ifeanyichukwu , Morojele Pholoho Justice
Published: August 2024

This article draws on the social identity theory to understand the real life schooling experiences of the migrant learners (from the Democratic Republic of Congo and Zimbabwe) within three South African schools. It adopted a qualitative, narrative research methodology, using open-ended interviews and photovoice as its methods of data collection. The findings reveal complex and pervasive dynamics of xenophobia. These took the form of denigrating stereotypical constructions of African migrants and resulted in the mistreatment, exclusion, and rejection of the African migrant learners. The study recommends further research on issues on African migrant learners schooling experiences in South Africa and for schools to embrace acceptance of African migrant learners for enhancing an inclusive schooling agenda.
Microbial Proteases: Sources, Significance and Industrial Applications
Authors: Ojo Omoniyi Olusola Abayomi , Dighitoghi Moro Dauphin , Bridget Afolabi Oyinkansola
Published: August 2024

Microbial enzymes are the preferred source to plants or animals for enzyme integration into biotechnological processes that enhanced sustainable development due to its cost- effective, ease of operation, re-use advantages and consistent production. Enzymes are biocatalysts, they accelerate a chemical reaction. They are used in industries such as biofuel, cleaning/detergents, food, pharmaceuticals, textiles, bioremediation and many more. The present review attempts to provide descriptive information on the recent development in enzyme technology for industrial applications as well as sustainable development.
Studies of Physicochemical and Bacteriological Characteristics of Drinking Water Quality in Shahdol University
Authors: Soni Abhishek , Tiwari Aditi , Choudhary Shalini , Shukla Manisha
Published: August 2024

The study conducted at Shahdol University and College aimed to assess the quality of tap water by analyzing its physical, chemical, and biological properties. Water samples were collected in triplicate from each station, and their average values for temperature, turbidity, electrical conductivity, suspended solids, and total solids were determined. The findings revealed that all physical parameters of the tap water samples met the standard limits set by the World Health Organization (WHO), indicating good quality water. Similarly, the chemical parameters of the tap water samples were within WHO recommendations. Microbiological analysis showed no colonies present, and total coliform bacteria levels were within WHO guidelines. Among the stations, S1 exhibited superior characteristics for drinking water compared to others. The study confirmed that tap water samples from S1, S2, and S3 in operation at Shahdol University and College met the requirements for water intended for human consumption. This underscores the importance of regular monitoring and maintaining water quality in educational institutions to ensure the health and well-being of students and staff.
Production of Thermostable β-Mannanase from Aspergillus niger using Submerged Fermentation
Authors: Chourasia Prashant , Gaherwal S.
Published: August 2024

Mannanases are one of the important lignocellulose degrading enzymes having potential biotechnological applications in a wide range of industries, including detergent industry, food and feed technology, coffee extraction, bioethanol production, pharmaceutical field, pulp and paper industry. The present study deals with the β-mannanase producing fungi. Fungal Strain Aspergillus niger was isolated from compost soil samples collected from Indore region and it was found to produce a significant amount of β-mannanase on solid agar plate and liquid media. Optimization was carried out for various physico-chemical parameters for maximum production of mannanase. After standardization we found that Aspergillus niger gave maximum production of mannanase (21U/ml) on the 10th day of incubation. Among different carbon and nitrogen sources 1% LBG and 0.5% yeast extract shows maximum enzyme production i.e. 21 U/ml and 39.89 U/ml respectively. The best temperature and pH for maximum yield of mannanase were 37oC (21.34 U/ml) and pH 6.0 (26.46 U/ml). The optimum inoculum size was found to be 107 spores/ml, giving maximum mannanase yield up to 22.63 U/ml. Mannanase was partially purified using ammonium sulfate fractionation and desalting using G25 column. The partially purified mannanase had optimum pH and temperature for activity at 3.8 and 75oC respectively and was found stable at 3-7 pH and 40-70oC temperature range.
Incidence of Mucormycosis, An Invasive Fungal Infection and its Relation with Covid-19 in A Tertiary Care Centre in Jammu
Authors: Priyanka Sharma Perika , Sikander Chairag Suharshi Gupta , Mukesh Kumar Shashi Sudhan Sharma
Published: August 2024

Mucormycosis, an invasive fungal infection has been seen to affect a large number of COVID-19 patients due to the overdosage, panic and injudicious use of corticosteroids among COVID-19 patients and presence of diabetes as a risk factor increases the chances of getting COVID-19 infection. The combination of Mucormycosis and COVID-19 infection has posed a double health threat to a collapsing healthcare system in India. Hence, the present study was conducted to study the incidence of Mucormycosis and its relation with COVID-19 so that awareness among the public can be generated and appropriate steps could be planned to combat the syndemic of COVID-19 and Mucormycosis. In our study, a total of 30 cases of Mucormycosis were reported, out of which Rhinocerebral Mucormycosis (RCOM) was the most common type 25(83.3%). Among the cases, 20 (66.6%) were male and 10 (33.33 %) were female. Maximum cases- 15 (45.8%) were in 51-60 years age group and among the cases, 18 (75%) were COVID positive. The present study was planned so that early diagnosis of such cases could be done, which would further help in providing appropriate treatment and hence subsequent reduction of morbidity and mortality.
Vulvovaginitis and Associated Factors in Pregnant Women Requesting A Cytobacteriological Examination of Cervical-Vaginal Sampling at the "Si Melon Laboratory" In The City of Yaoundé - Cameroon
Authors: A. Mbogning Therence , G. Matchuenkam Sonia , E. Feudjieu Gaizirene , W. Kom Christrelle , T. Wokfa Carelle , Adjim Ngana Karyom Djim , Y. Tchokouaha Lauve R. , D. Tchamgoue Armelle , F. Tchinda Cedric , A. Agbor Gabriel
Published: August 2024

Vulvovaginitis, a significant public health issue, poses risks during pregnancy. This study identifies the germs causing vulvovaginitis and their associated factors in pregnant women at the Si Melon Laboratory in Yaoundé, Cameroon. In a 04-week study, vaginal secretions from 55 pregnant women were analyzed using Amsel’s criteria, Nugent’s scoring, and culture techniques. Antimicrobial sensitivity was assessed via disc diffusion, with statistical significance set at a p-value ≤ 0.05. Of the 55 women included in this study, 72.7% were carriers of germs involved in vulvovaginitis, and 52.7% were infected with at least two. Gardnerella vaginalis (44.5%), Candida albicans (24.7%), and Mobiluncus spp (16%) were predominant. Coinfections were common, particularly Gardnerella vaginalis/Mobiluncus spp (20.8%) and Gardnerella vaginalis/Candida spp (13.8%). Staphylococcus strains were sensitive to Ceftriaxone, Imipenem, and Amoxiclav, while Candida strains responded well to Econazole, Miconazole, Fluconazole, and Nystatin. Poorly maintained underwear and inadequate intimate hygiene were significant factors associated with infection. The study highlights the prevalence of various germs in vulvovaginitis among pregnant women, linked to suboptimal hygiene practices. Emphasizing proper hygiene could prevent potential complications and promote maternal well-being.
The Quantitative Assessment of Bacterial Species from Soil Samples through Real Time PCR
Authors: Tomar Anjali , Bharati Deepak , Rehan Samrah , Vishwakarma Rohit Kumar , Shukla Manisha
Published: August 2024

This study assessed microbial populations in soil samples from the Bhopal, Capital, Madhya Pradesh, India using traditional dilution plating, supplemented with qPCR for molecular insights. The CFU counts ranged from 6.3 to 8.2 log10 CFU/gm, with sample 7 having the highest and sample 4 the lowest bacterial load, highlighting variability due to soil properties and environmental conditions. qPCR analysis showed an inverse relationship between CFU counts and CT values, confirming higher DNA concentrations with higher viable bacterial counts. This dual approach of combining CFU and qPCR methods offers a comprehensive understanding of microbial presence, consistent with prior research findings. High bacterial counts, as seen in sample 7, suggest healthy soil with robust nutrient cycling and organic matter decomposition, while lower counts in sample 4 may indicate less favorable conditions for microbial growth. Future studies should incorporate advanced molecular techniques, like high-throughput sequencing, to fully capture soil microbial diversity.
An Analysis of Clinical, Haematological, Biochemical Profile in Dengue IgM Antibody Positive Patients at a Tertiary Care Hospital
Authors: Rajalakshmi Kesavan , Asha A. , Ananthi B.
Published: August 2024

Dengue fever is a seasonal and emerging acute mosquito-borne arboviral illness affecting tropical and subtropical countries. Prevalence of dengue infection increase in monsoon and post monsoon period. These infections may be asymptomatic or may lead to classical dengue fever (DF), or dengue hemorrhagic fever (DHF) with or without shock. Owing to lack of any diagnostic marker and any specific clinical symptoms to identify cases that will have a severe disease outcome, early diagnosis and close monitoring with symptomatic treatment is necessary. Aims and Objectives: To estimate the prevalence of dengue and to co-relate the serological, clinical, haematological and biochemical data for early diagnosis of severity of dengue infection. Materials and Methods: A cross sectional study was conducted over a period of 6 months from April 2023 to June 2023at ACS Medical College and Hospital, Chennai, a tertiary care center. Serological analysis of 30 dengue IgM antibody positive serum samples by capture ELISA method and correlation between different clinical, serological, hematological and biochemical parameters was done using SPSS software. Results: Out of 30 Dengue IgM positive patients, 26 (86.6%) were males, with mean age group of 15-25 years. 29 (96.6%) patients had fever and 13 (43.3%) had vomiting. 1 patient had co infection with malaria. Thrombocytopenia was observed in 23(76.6%) and leucopoenia in 17 (56.6%) patients. 22 (73.3%) patients had elevated transaminases. Conclusion: This study highlights the importance of clinical history, examination and investigations in timely diagnosis. This along with, helps in early treatment and reduces morbidity & mortality rate.
Biocatalytic Preparation of Chiral Hydroxy Esters using Entomogenous Fungi: Bio-reduction of Keto Esters by Tochukaso and Related Species
Authors: Ishihara Kohji , Takaki Yu , Masuoka Noriyoshi , Shimoda Kei
Published: August 2024

To research the potential ability of tochukaso and related species to act as biocatalysts, we screened 10 entomogenous fungal strains. The recommended medium (Potato Dextrose broth) and a synthetic medium (PGO medium) were tested as the liquid media for culturing these fungi. Four strains (NBRC33061, 100684, 103832, and 109003) cultured using the PGO medium showed a good growth. The stereoselective reduction of ?- and ?-keto esters by these four strains was also investigated, and they were found to be able to reduce various ?-keto esters. Specifically, the reduction of ?-keto esters by the PGO-cultivated Isaria cicadae NBRC33061 strain in the presence of L-glutamate as an additive yielded corresponding ?-hydroxy esters with a high conversion ratio and in excellent enantioselectivity. Furthermore, it was found that the PGO-cultivated NBRC109003 strain in the presence of L-glutamate stereospecifically reduced ethyl 2-methyl-3-oxobutanoate to (2S, 3S)-2-methyl-3-hydroxybutanoate, i.e., only one of the four theoretically possible isomers. Overall, tochukaso and related species were shown to have a great potential for application as biocatalysts for the stereoselective reduction of carbonyl compounds.
Growth and Germination of Barley Seedlings (Hordeum vulgare) using local Freshwater Algae
Authors: McCullen Melanie , Awal Sadiqul , Christie Andrew
Published: August 2024

While it is true that chemical fertilizers are effective when it comes to increasing production and compensating for a lack of resources, they do result in soil, water, and biological resource depletion and destruction, and the search for alternatives is a considerable focus of much research around the globe. It has become increasingly important to explore the use of beneficial biological organisms, including microbes (which microalgae are generally accepted as being classified as) in industrial agriculture as agents that may assist with fertilization, since they can also contribute to sustainable crop production and potential improvements in food safety. In this study, the potential for freshwater microalgae to act as biofertilizers was explored with a view to improving yield quality and productivity whilst minimizing environmental pollution. The purpose of this study was to determine whether freshwater algae (Pseudo coccomyxa sp and Chlorella sp) could be used to increase barley (Hordeum vulgare) seed germination rates and plant growth through the process of biofertilization. A comparison of barley seed growth with algae applied as a fertilizer before sowing was conducted in three control vessels and three treatment vessels. Weekly monitoring and watering schedules were followed while the barley germinated and grew. There was a significant difference in height, root length, and fresh and dry root, leaf, and stem weights between the experimental and control plants. After six weeks, barley seedlings treated with freshwater algae grew the fastest and gained the most weight. Treatment plants averaged 48 cm in length, while control plants averaged 37 cm. As a result of the treatment, the total fresh weights of the plants were heavier (0.37g) than those of the control plants. In addition, microalgae treated soil retained essential nutrients even after plants were removed at the end of the experiment.
Incidence and Aetiology of Bloodstream Infections in Intensive Care Unit Patients at National Medical College, Birgunj, Nepal
Authors: Shankar Gupta Ravi , Pokhrel Shisir , Jha Chandana , Kishor Karn Naval
Published: August 2024

Bloodstream infection (BSI) is among the most common acquired illnesses in intensive care unit (ICU) patients and remains one of the most important causes of morbidity and mortality. The current study was aimed to evaluate the incidence of central line?associated bloodstream infections (CLA-BSIs) and bacterial aetiology among the patients admitted at ICU. This study was conducted on randomly selected 1030 patients admitted in the ICU of National Medical College and Teaching Hospital Birgunj, Nepal, from 15thApril 2023to 14th March 2024. The incidence of bloodstream infection and bacteriological profile were done by following standard technique and precautions. This study revealed that the incidence of CLA-BSI was 12.04 per 1000 catheter days. The current study revealed that Gram-negative organisms (66.67%) were the most common organisms associated with the incidence of CLA-BSI in ICU patients which followed by gram-positive organisms (27.08%) and fungal organisms (6.25%). The current study findings also reveal that Salmonella enterica, Escherichia coli, Staphylococcus aureus and Enterococcus spp. were the most common causative agents for CLA-BSI episodes in the ICU patients. It may be prudent to turn our attention to infections caused by these pathogens that may require different approaches to prevention, e.g., optimizing central line maintenance practices.
Compatibility and Physical Stability of Mixtures of Pre-Emergent Herbicides with the Insecticide-Nematicide Mocap® for the Control of Weeds, Symphylids and Nematodes in Pineapple (Ananas comosus cv MD-2)
Authors: Herrera Daniel , Paniagua Fernán , Abarca Jorge , Morales Dyan , Cortes Oscar , Delgado Juan , Araya Mario
Published: August 2024

In Costa Rica, pineapple production is affected among other soil pests, by symphylids (Scutegerella spp. Hansiniella spp.) and nematodes (Pratylenchus ssp., Helicotylenchus spp.) that cause production losses. To prevent the presence of soil pests, insecticides-nematicides are applied. In addition, due to the high cost of labor and the reduced yield in manual weeding, it is common to apply pre-emergent herbicide before planting. Ideally, a single application targeting both approaches would be desirable to save water, reduce costs, and maximize labor. The present investigation studied the compatibility and physical stability of solutions that include pre-emergent herbicides (oxyfluorfen, hexazinone, ametrine, diuron) and the insecticide-nematicide Mocap® 72EC. Subsequently, the commercial application of a mixture of oxyfluorfen + Mocap® was carried out to verify if it prevents the initial presence of weeds and pests in the pineapple planting establishment (Ananas comosus cv MD-2). The results showed that the combination of the herbicides with Mocap® 72EC in a volume of 2400 liters per hectare was compatible and keep the spray solution stable in all cases. The field test, with the oxyfluorfen and Mocap® solution, confirmed the biological efficacy of the oxyfluorfen herbicide, where no weeds were found in the evaluation of 10 linear meters of bed 60 days after planting. Similarly, it was confirmed that Mocap® prevented symphylids infestation, finding 0% incidence and a 48% of the total phytoparasitic nematode population reduction (P= 0.0017) at 60 days of planting age, when compared to the untreated control. Therefore, the evaluated pre-emergent herbicides and the insecticide-nematicide Mocap® solutions can be applied given the common occurrence of symphylids, nematodes and weeds in the establishment of pineapple plantations.
A Case Study on Soil Health Assessment Under Different Annual and Perennial Cropping System.
Authors: Kumar Sanjeev , Tripathi Varun , Pandey Jyoti
Published: August 2024

A field experiment was conducted on agriculture field located 2km away from NH-24 Delhi-Lucknow highway near Invertis village from Invertis university Bareilly (Uttar Pradesh). The experiment was conducted in a random manner with different combinations of organic and inorganic nutrients to know the effect of morphological characteristics, physical properties, chemical properties present in soil. At 0-15 cm depth the soil moisture content of soil in top layer was not affected significantly due to different cropping systems. However, the highest soil moisture content was recorded under guvava orchard. The maximum bulk density was recorded with cropping system Rice-wheat which remain at par with Rice-Berseem+Mustard and rice-sugarcane-ratoon-wheat. At 0-15 cm soil depth maximum porosity was recorded under the Guvava orchard which was found significantly at par with popular plantation. The lowest value of maximum porosity was found with grassland cropping system. At 15-30 cm depth the maximum porosity was recorded guvava orchard. The highest pH value was recorded under guvava orchard. The highest organic carbon was recorded under guvava orchard at both 0-15 and 15-30 cm soil depth. The maximum available nitrogen was recorded with guvava orchard at both 0-15 and 15-30 cm soil depth. At 0-15 cm soil depth the available potassium was influenced significantly due to various cropping systems. At 0-15 cm soil depth agricultural treatment CS 6 which was found statistically at par with guvava orchard and both were found to be comparable to each other. At 15-30 cm soil depth the available phosphorus among all the system was found comparable to each other. The highest available phosphorus was obtained with the agricultural (CS 6) which was followed by the popular plantation (CS 4). At 0-15 cm depth, the available sulphur was influenced significantly due to various cropping systems. The maximum available sulphur was recorded under the system guvava orchard CS 3 which was higher than rest of the treatments. At 15-30 cm soil depth, the available sulphur was affected significantly due to various cropping systems. The maximum value of available sulphur was obtained with the system Guava orchard (CS 3). Agricultural (CS 6) which remained at par with guvava orchard (CS 3) and both these treatments were found significantly superior over the rest of the systems.
Analysis of Medicinally Important Phytocompounds from Adina cordifolia Roots
Authors: Raypa Pratima , Verma A. K. , Tewari Salil , Dubey Ashutosh
Published: August 2024

The present study aimed to investigate the bioactive phytochemical constituents of Adina cordifolia through GC-MS analysis. To identify the pharmacologic important compounds present in Adina cordifolia roots, extracts were prepared using cold extraction method in different solvents of different polarity, namely chloroform, ethyl acetate, acetone and methanol. Gas chromatography-mass spectrometry (GC-MS) was performed to identify the phytocompounds present in the plant extracts using the National Institute of Standards and Technology (NIST) library. A wide range of fatty acids and plant compounds with antibacterial, antifungal, antiamoebic and anti-inflammatory effects were also identified. The study concludes that Adina cordifolia contains many biologically important compounds and can therefore be recommended as a medicamentously important plant.
Effect of Different Doses of γ-rays (50 Gy, 100 Gy, 150 Gy, 200 Gy& 400 Gy) in M3 Generation of Soybean (Glycine max (L.) Merril) Genotypes
Authors: Kumari Priyanka , Chakraborty Manigopa , Chakravarty Milan Kumar
Published: August 2024

Soybean genetic variation improvement is important for the development of superior cultivars. One of the greatest challenges in mutation breeding is random (uncontrolled) nature of induced mutagenesis. Large population requirement for desired mutant selection brings intensive labor. Choice of appropriate mutagen is one of the deciding factors on succession of the mutation breeding program. Physical, chemical, or biological agents are viable alternatives. Among physical mutagens ionizing radiation sources, particle (electrons, protons, neutrons, alpha and beta particles) or electromagnetic (X-rays, gamma rays), are widely used. Ionizing radiation interacts with genetic material and cause mutations on DNA sequences. Magnitude of mutagenic effect is proportional to the radiation dose Physical mutagen are still improving and mutation breeding proves its value to be fast, flexible, and viable in crop sciences. It is crucial to determine and optimize the effective radiation dose based on experimental plant variety, plant part, and radiation source. 80% of mutation breeding studies prefer physical mutagens and of 60% of this use gamma radiation. In both the soybean varieties, BSS-2 & RKS-18 the spectrum of viable mutation was high at lower dose of Gamma rays. In variety, BSS-2 twining stem, tricotyledon, tetracotyledon were observed while in M3 generation. In RKS-18 stem mutants were not observed. Whereas in the variety, BSS-2, the spectrum of viable mutations was high at dose 100 Gy (14) while in RKS-18, the spectrum of viable mutations was high at lower dose 50 Gy (16).
Interplay Between Natural Compounds of Mundulea sericea Bark Extract in Combating Aleurodicus dispersus, Spiralling Whitefly an Invasive Pest of Telangana
Authors: Grace Beena Zakkum , Madhavi M. , Swamy S. Guru
Published: August 2024

An invasive pest, Spiralling whitefly, Aleurodicus dispersus incidence has been noticed on Guava, Mango, papaya, Banana, coconut and pomegranate crops in Telangana, India during 2020-22,later it spread to ornamental plants. Aleurodicus dispersus, spiralling white fly was observed on the underside of leaves along with the presence of white waxy material honey dew around the whitefly infested area, sooty mould formation and drying of infested leaves observed in infected plants. By targeting the eggs of spirling whiteflies, the life cycle and the population of Aleurodicus dispersus is reduced. This is the first study in Telangana to examine the efficacy of Mundulea sericea bark and leaves as a ovicidal agent against spiralling whitefly that is a major threat to Agriculture and Horticulture crops, after exposing the plant extract for 24 hrs egg mortality was observed. This discovery has significant implications for pest control, its a eco-friendly alternative to synthetic chemical insecticides.
Blood Glucose Levels in Individuals Infected with Soil-Transmitted Helminths in Padang West Sumatera, Indonesia
Authors: hayati Nur , Rusjdi Selfi Renita , Nofita Eka
Published: August 2024

Chronic infections in the human gut are most commonly caused by helminths spread through soil. Worms have been found to provide immunity to several illnesses, including inflammatory diseases and metabolic syndrome. This study aims to investigate adult members of scavenger families who have been exposed to soil-transmitted helminth infections in terms of their fasting blood glucose (FBG) levels. To check for soil-transmitted helminths, feces are examined using the direct method using iodine, and the Kato Katz method to count the number of eggs per gram of feces. The hexokinase enzymatic approach was used to test blood glucose levels during a fast. Infections with soil-transmitted helminths were categorized as mild in all study participants. When soil-transmitted helminth infections were compared to controls, there was a statistically significant drop in FBG levels (p<0.05). Thus, it may be said that soil-transmitted helminth infections spread through the soil can lower adult blood glucose levels.
PENGARUH KUALITAS PRODUK, HARGA, DAN KUALITAS PELAYANAN TERHADAP KEPUASAN KONSUMEN PADA RUMAH MAKAN PAWON BROMO MALANG
Authors: Maulani Yulita Dwi , Nurfarida Iva Nurdiana , Suroso Adi
Published: August 2024

Penelitian ini bertujuan untuk mengetahui pengaruh kualitas produk, harga, dan kualitas pelayanan secara simultan dan parsial terhadap kepuasan konsumen. Penelitian ini merupakan penelitian kausal komparatif (causal comparative research) yang memiliki tujuan untuk mengetahui kemungkinan adanya hubungan sebab akibat antar variabeldengan menggunakan pendekatan kuantitatif. Populasi dalam penelitian ini merupakan konsumen pada rumah makan Pawon Bromo Malang dengan jumlah sampel yang diambil sebanyak 120 responden menggunakan metode accidental sampling untuk menentukan sampel penelitian. Instrumen penelitian dinyatakan valid dan reliabel dengan uji validitas dan reliabilitas. Teknik pengumpulan data menggunakan kuesioner yang disebarkan kepada sampel penelitian yang kemudian dianalisis menggunakan analisis regresi linear berganda dengan bantuan SPSS. Hasil penelitian ini menunjukkan secara simultan persepsi kualitas produk, harga, dan kualitas pelayanan berpengaruh signifikan terhadap kepuasan konsumen. Secara parsial persepsi kualitas produk, harga, dan kualitas pelayanan berpengaruh signifikan terhadap kepuasan konsumen.
ELASTISITAS KESEMPATAN KERJA SEBELUM DAN SESUDAH MASA PANDEMI COVID-19
Authors: Dwiyoso Wahyudi, Hertoto , Sulistiyanti Sulistiyanti
Published: August 2024

Penelitian ini bertujuan untuk mengukur perubahan kesempatan kerja yang tercipta dari pertumbuhan ekonomi, upah minimum provinsi, dan tingkat partisipasi angkatan kerja. Dengan menggunakan metode regresi berganda, ditemukan bahwa pertumbuhan ekonomi berpengaruh positif terhadap kesempatan kerja, dan tingkat upah minimum provinsi berpengaruh negatif terhadap kesempatan kerja. Akan tetapi tingkat partisipasi angkatan kerja tidak berpengaruh signifikan terhadap kesempatan kerja. Hasil penelitian juga menunjukkan bahwa elastisitas kesempatan kerja sebelum dan sesudah pandemi, tidak berbeda signifikan dengan saat pandemi. Namun demikian, pandemi Covid-19 berdampak langsung pada penurunan pertumbuhan ekonomi kecuali di Provinsi Maluku Utara, Sulawesi Tengah, dan Papua. Penurunan kesempatan kerja juga terjadi di beberapa wilayah terutama di DKI Jakarta, Papua dan Jawa Barat, sementara banyak juga wilayah yang mampu mempertahankan tingkat kesempatan kerjanya.
PENGARUH KESELAMATAN DAN KESEHATAN KERJA (K3), PELATIHAN DAN KOMPENSASI TERHADAP KINERJA KARYAWAN
Authors: Cahyaniwati Aprillia Rizka , Sedyastuti Kristina , Suharso Arien Anjar Puspitosari , Graha Andi Nu
Published: August 2024

Penelitian ini merupakan penelitian kuantitatif yang dilakukan dengan tujuan mengetahui apakah ada pengaruh Keselamatan dan Kesehatan Kerja (K3), Pelatihan dan Kompensasi terhadap Kinerja Karyawan pada PT. Budi Karta.  Data yang diperoleh pada penelitian ini adalah data primer diperoleh dari penyebaran kuesioner kepada para karyawan. Sampel yang digunakan sejumlah 40 responden pegawai PT. Budi Karta. Analisis data menggunakan regresi linier berganda serta menggunakan uji asumsi klasik dan uji hipotesis menggunakan bantuan program SPSS. Hasil penelitian ini menunjukkan bahwa secara simultan Keselamatan dan Kesehatan Kerja (K3), Pelatihan dan Kompensasi terhadap Kinerja Karyawan pada PT. Budi Karta berpengaruh positif signifikan dan secara parsial Keselamatan dan Kesehatan Kerja (K3) berpengaruh positif signifikan terhadap kinerja karyawan, pelatihan berpengaruh positif signifikan terhadap kinerja karyawan dan kompensasi berpengaruh positif signifikan terhadap kinerja karyawan PT. Budi Karta.
Konsep Kebahagiaan Perspektif Buya Hamka Dalam Kitab Tafsir Al-Azhar
Authors: Hanifah Rofiatul
Published: August 2024

Perkembangan arus modern membawa perubahan dunia menjadi serba cepat dan mudah. Segala hal dapat terwujud hanya dengan kendali jempol saja, sehingga zaman ini diperkirakan menjadi zaman kenikmatan dan kebahagiaan. Namun, pada realitanya banyak manusia tidak merasakan kebahagiaan itu, banyak peristiwa-peristiwa baru terjadi dan belum pernah ada pada masa modern seperti maraknya korupsi, pernikahan sesame jenis gay, seorang anak membunuh ayahnya serta peritiwa lainnya. Dalam proses mendapatkan kebahagiaan, manusia memiliki cara yang berbeda-beda untuk mengusahakannya. Banyak ilmuwan, filsuf, maupun tokoh lain yang berpendapat tentang makna kebahagiaan. Namun, kaitannya dengan hal ini penulis ingin meneliti dari sudut pandang mufassir tentang kebahagiaan(As-sa’a>dah) dalam Al-Quran mengandung nuansa anugerah Tuhan setelah terlebih dahulu mengarungi kesulitan. Kata as-sa’a>dah sering digunakan dalam pemaknaan bahagia yang sifatnya dunia dan akhirat. Sebagaimana kebahagiaan duniawi bisa menjadi salah satu jalan menuju kebahagiaan ukhrawi. Berbeda halnya dengan kata fala>h (beruntung), naja>t (selamat), naja>h (berhasil).
Fatores relacionados à arquitetura que influenciam a decisão de compra de residências unifamiliares em condomínios fechados
Authors: Oliveira Maurício , Vieira Romano Fabiane
Published: August 2024

A análise do atual cenário imobiliário no Brasil, assim como fatores demográficos, demonstra o crescente investimento de incorporadoras e investidores imobiliários na construção de casas para venda, principalmente em condomínios fechados. Nesse sentido, observou-se a oportunidade de estudo dos comportamentos e anseios dos consumidores de imóveis residenciais de alto padrão à venda nesse tipo de empreendimento. Por meio de uma revisão sistemática de literatura buscou-se inicialmente identificar teses e dissertações em língua portuguesa, disponíveis nas bases de dados nacionais, a fim de se encontrar informações para compreender as demandas dos potenciais compradores de residências unifamiliares, sobretudo no que tange a aspectos arquitetônicos e construtivos decisivos para a tomada de decisão. O tratamento dos dados foi feito por análise bibliométrica, incluindo a tabulação dos dados de dezesseis buscas nas plataformas digitais escolhidas, resultando em trinta e seis trabalhos selecionados, o que permitiu identificar as principais instituições que publicam sobre a temática; as principais palavras-chaves utilizadas nas publicações; e áreas que dissertam sobre o assunto de imóveis residenciais para a venda.
Metabolite biomarkers present in serum and urine predict alterations in skeletal muscle associated with sarcopenia.
Authors: Andrade-Vieira Rafaela , Feridooni Hirad , Teixeira Alyne , Deska-Gauthier Dylan , Chang Xingjian , Karakach Tobias , Moyer Rebecca , Frampton John
Published: August 2024

Sarcopenia, the progressive loss of muscle mass and strength with age, is associated with many adverse health outcomes in aging populations decreasing greatly health span. Early detection of sarcopenia is critical for initiating preventative strategies to stop muscle deterioration. Current methods for detecting the onset of sarcopenia are inaccessible and costly, creating a barrier to routine screening. Here, we examine serum samples from a group of 360 community-dwelling individuals aged 50 to 70 who previously completed the international physical activity questionnaire (IPAQ). We further analyze urine samples from a group of 60 individuals, who completed standard physical performance battery (SPPB) tests, dual-energy x-ray absorptiometry (DEXA), IPAQ, and an additional questionnaire. We demonstrated for the first time that a panel of biomarkers composed by glutamate, xanthine, taurine, succinate, and carnitine are linked to early alterations in muscle metabolism and can be used to monitor muscle degeneration. These metabolites are detectable in urine and are predictive of sarcopenia as compared to DEXA and physical assessments. This panel serves as a sensitive and objective monitoring tool for assessing muscle metabolism, enabling more effective and accessible management of muscle-wasting conditions such as sarcopenia.
Clinical outcomes of endovascular treatment in patients with M2 segment occlusion of the middle cerebral artery of different etiologies: A retrospective study
Authors: Xu Yaning , Jin Wangsheng , Liu Chengchun , Zhao Qiuju , Li Wei , Zhang Meng
Published: August 2024

Background
Distal medium vessel occlusion may lead to severe neurological deficits. The aim of this study was to investigate the differences in endovascular treatment (EVT) procedure and their impact on clinical outcomes in patients with different etiologies of the M2 segment of the middle cerebral artery (M2-MCA) occlusion.
Methods
We conducted a retrospective analysis of patients with M2-MCA occlusion treated with endovascular treatment at Army Medical Center from January 2015 to July 2023. Patients were divided into atherosclerosis group and embolization group, and we determined the etiology of stroke based on the imaging features during EVT. Procedure-related outcomes included recanalization rates, treatment modalities, and procedural complications. Clinical outcomes included the good outcome (modified Rankin Scale score 0–2) at 90 days, incidence of symptomatic intracranial hemorrhage (sICH) and any intracranial hemorrhage within 24 hours, and mortality at 90 days.
Results
A total of 81 patients were included in the analysis, and the numbers of patients in the atherosclerosis and embolization groups were 20 and 61, respectively. Patients in the embolization group treated with more number of mechanical thrombectomy (2 [1–3] vs 1 [1–2], P = 0.028). However, the total number of EVT (2.5 [1–4] vs 2 [1–3], P = 0.036) and the proportion of patients treated with rescue therapy (50.0% vs 1.6%, P<0.001) were significantly greater in the atherosclerosis group. The recanalization rate and incidence of procedural complications were not significantly different between the two groups. The good outcome at 90 days, incidence of sICH and any intracranial hemorrhage within 24 hours, and mortality at 90 days were also no statistical difference between the two groups.
Conclusion
For patients with M2-MCA occlusion of different etiologies, neurointerventionalists may choose different EVT modalities. There were no significant differences in recanalization rates, procedural complications, or clinical outcomes.
LIFESTYLE DISEASES AND NUTRACEUTICAL INTERVENTIONS: MECHANISMS AND CLINICAL USES
Authors: Tiwari Dr Jayanti , Yadav Dr Vimal Kumar , Singh Dr Nirupama , Shukla Dr Ajay Kumar
Published: August 2024

In recent decades, the rise of lifestyle diseases, such as obesity, diabetes, cardiovascular diseases, and certain cancers, has emerged as a significant public health concern worldwide. These diseases, often linked to sedentary lifestyles, poor dietary habits, and environmental factors, are leading causes of morbidity and mortality. Lifestyle Diseases and Nutraceutical Interventions: Mechanisms and Clinical Uses provides a comprehensive exploration of the relationship between lifestyle factors and the onset of chronic diseases, emphasizing the potential of nutraceuticals as preventive and therapeutic interventions. This edited volume brings together contributions from experts in the fields of nutrition, biochemistry, pharmacology, and clinical medicine to offer a multidisciplinary perspective on the mechanisms by which lifestyle choices influence disease development. The book delves into the science behind nutraceuticals—bioactive compounds derived from food sources—and their role in modulating disease pathways. It explores how these compounds can be integrated into clinical practice to support health and manage disease. Key topics include the impact of diet on metabolic health, the role of specific nutraceuticals in reducing inflammation and oxidative stress, and the potential for personalized nutrition strategies in preventing lifestyle diseases. Case studies and clinical trials are presented to illustrate the practical applications of nutraceuticals in various therapeutic contexts. Lifestyle Diseases and Nutraceutical Interventions serves as an essential resource for researchers, healthcare professionals, and policymakers interested in the intersection of nutrition and chronic disease management. It provides evidence-based insights into how lifestyle modifications, supported by nutraceutical interventions, can contribute to the prevention and treatment of some of the most prevalent health challenges of our time.
SUSTAINABLE CONSTRUCTION MATERIALS
Authors: Gupta Shashank , Sharma Aditya , Shukla Dr Nidhi , Tripathi Dr Priyalika , Singh Dr Gourav Kumar
Published: August 2024

The construction industry stands at a pivotal crossroads. With the pressing challenges of climate change, resource depletion, and environmental degradation, the demand for sustainable construction practices has never been more urgent. This edited book, "Sustainable Construction Materials," brings together the collective expertise of leading researchers, practitioners, and innovators to explore the cutting-edge advancements and applications of sustainable materials in construction. The impetus behind this book is the recognition that our traditional building practices are no longer viable if we are to ensure a sustainable future. The selection and utilization of construction materials have far-reaching implications on environmental health, economic development, and social well-being. This compendium aims to provide a holistic understanding of sustainable construction materials' principles, practices, and potential, serving as both a resource and a guide for industry professionals, academics, policymakers, and students. This book is organized into thematic sections, each dedicated to a specific aspect of sustainable construction materials. From the use of recycled and reclaimed materials to innovative biomaterials and advanced composites, each chapter offers an in-depth analysis of these materials' environmental, economic, and practical benefits. The contributions within this book highlight not only the technological advancements but also the regulatory frameworks, market dynamics, and case studies that illustrate the successful implementation of sustainable materials in diverse contexts.