bluuebunny/crossref_metadata_2025 huggingface dataset:
Haber Sınıflandırma Sistemlerinde Naive Bayes ve Makine Öğrenmesi Algoritmaları Arasında Performans Karşılaştırması
Authors: Veziroğlu Merve , Bucak İhsan
Published: February 2025

Dijital içerikteki artış, özellikle haber sınıflandırma gibi metin odaklı görevlerde otomatik sınıflandırma yöntemlerine duyulan ihtiyacı büyük ölçüde artırmıştır. Bu noktada Doğal Dil İşleme (DDİ) teknikleri, büyük veri setlerinde insan müdahalesi olmaksızın verimli sonuçlar üretebilme potansiyeline sahiptir. Bu çalışma, haber başlıklarını kategorilere ayırmayı amaçlayan, Python ile geliştirilmiş bir Naive Bayes (NB) tabanlı sınıflandırma sistemini tanıtmaktadır. NB algoritmaları, basitlikleri ve hızlı hesaplama özellikleri nedeniyle metin sınıflandırma problemlerinde öne çıkmaktadır. BBC News başlıklarından oluşan veri kümesi; teknoloji, iş dünyası, spor, eğlence ve siyaset gibi farklı kategorileri kapsamaktadır. Veri ön işleme sürecinde metin temizleme, durdurma kelimelerin çıkarılması ve Sayım Vektörleştirme ile metnin sayısal verilere dönüştürülmesi gibi adımlar yer almıştır. Bu süreç, doğru ve etkili sınıflandırma için kritik bir rol oynamaktadır. Çalışma kapsamında beş farklı NB varyantı incelenmiştir: Gaussian, Multinomial, Complement, Bernoulli ve TAN. Sonuçlar, Multinomial NB’nin %98.53 doğruluk oranıyla en iyi performansı sergilediğini ortaya koymuştur. Complement NB %98.31, TAN %98.20, Bernoulli %96.74, Gaussian NB ise %91.79 ile %92.92 arasında değişen doğruluk oranlarına sahiptir. Bunun yanı sıra NB algoritmaları, Lojistik Regresyon, Rastgele Orman, Doğrusal Destek Vektör Sınıflandırıcısı ve Çok Katmanlı Algılayıcı gibi gelişmiş makine öğrenimi algoritmalarıyla karşılaştırılmıştır. Çok Katmanlı Algılayıcı, %98.31 doğruluk oranı ile öne çıkarken, diğer algoritmalar da %97’nin üzerinde başarı elde etmiştir. Bu çalışma, NB algoritmalarının haber sınıflandırma problemlerinde güçlü, güvenilir ve etkili bir çözüm sunduğunu göstermektedir. Özellikle Multinomial ve Complement NB varyantları, yüksek doğruluk oranları ile dikkat çekmektedir. Gelecekteki araştırmalar, daha geniş veri setleri ve yeni yaklaşımlar ile bu algoritmaların performanslarını daha da geliştirmeyi hedeflemektedir.
TarBIoT KDS: Akıllı Tarım Uygulamaları için Blokzincir ve IoT teknolojileri ile Gerçek zamanlı Karar Destek Sistemi Tasarımı
Authors: Ayberkin Doruk
Published: February 2025

Bu çalışma, tarım sektöründeki küresel zorlukları ele almak için yenilikçi bir yaklaşım sunmaktadır. Araştırma, blokzincir ve Nesnelerin İnterneti (IoT) teknolojilerini entegre ederek, tarımsal verilerin toplanması, güvenli bir şekilde depolanması ve analiz edilmesi için kapsamlı bir sistem önermektedir. TarBIoT olarak adlandırılan bu sistem, çeşitli sensörlerden elde edilen toprak ve iklim verilerini gerçek zamanlı olarak işleyerek, çiftçilere ve diğer paydaşlara yönelik bir karar destek mekanizması sunmaktadır. Sistemin temel bileşenleri arasında IoT sensör ağı, blokzincir altyapısı, veri işleme ve analiz modülü ile karar destek sistemi bulunmaktadır. Bu entegre yapı, tarımsal üretimde verimliliği artırma, kaynakları optimize etme ve çevresel sürdürebilirliği destekleme potansiyeli taşımaktadır. Blokzincir teknolojisinin sağladığı şeffaflık ve güvenilirlik, verilerin tüm paydaşlar arasında güvenli bir şekilde paylaşılmasına olanak tanırken, karar destek sistemi, bu verileri anlamlı ve uygulanabilir bilgilere dönüştürmektedir. Çalışma, önerilen sistemin simülasyonunu gerçekleştirerek, su seviyesi, nem oranı, toprak pH değeri gibi kritik tarımsal parametrelerin izlenmesi ve analiz edilmesindeki etkinliğini değerlendirmektedir. Sonuçlar, TarBIoT sisteminin, akıllı tarım uygulamalarının geliştirilmesinde, gıda güvenliğinin artırılmasında ve sürdürülebilir tarım pratiklerinin yaygınlaştırılmasında önemli bir rol oynayabileceğini göstermektedir. Bu araştırma, tarım sektöründeki dijital dönüşümü hızlandırma ve veri odaklı tarım uygulamalarını yaygınlaştırma potansiyeli taşımaktadır.
Treatment of the spin cycle effluent using electrocoagulation and granular activated carbon
Authors: Chodnekar Shamik Prabhu , Mutnuri Srikanth
Published: February 2025

Given the rising demand for freshwater and its limited availability, treating and reusing household wastewater is becoming increasingly crucial. One way to accomplish this is to treat and reuse the spin cycle effluent from washing machines. The spin cycle, being the last washing cycle, yields comparatively cleaner effluent, necessitating less intensive treatment, rendering it an attractive target for treatment and reuse. This study presents the first instance of characterizing and treating this effluent. The average values for the spin cycle effluent for chemical oxygen demand (COD), biochemical oxygen demand, pH, conductivity, turbidity, total nitrogen (TN), and orthophosphate were found to be 241.8 ± 88.4 ppm, 36.9 ± 14.3 ppm, 7.2 ± 0.9, 223.4 ± 46.7 μS/cm, 85.9 ± 20.1 NTU, 7.2 ± 3.1 ppm, and 4.6 ± 1.7 ppm, respectively. The treatment study was conducted at a 2-liter scale using aluminum electrodes in a bipolar setup and utilized three liquid and three solid detergents. The treatment process consisted of sequential utilization of electrocoagulation flocculation and granular activated carbon which resulted in an excellent treatment, with a 92.7 ± 3.6% reduction in COD, an 87.2 ± 9.7% reduction in TN, a 91.4 ± 2.9% reduction in orthophosphate, and a 93.3 ± 4.7% reduction in turbidity. Utilizing the reuse potential of the spin cycle effluent with this process will allow households to actively contribute to sustainable water management practices.
A Report on Nanomaterial Catalysed Environmentally Benign Synthesis of Pyrido[2,3-d]pyrimidine Derivatives
Authors: Rishi Harsha , Singh Pratap , Sain Anushka , Kanwar Neeraj , Bhargava Sangeeta
Published: February 2025

Nowadays, green chemistry is a fast developing innovative field that leads to eco-friendly results for
the future of science and technology. Designing reactions based on green principles is of great interest with
exceptional physical, biological, or pharmaceutical properties. Replacement of chemical methods with environmentally
benign processes for the sake of the environment is a need of society. Heterocycles are a fundamental
component of many pharmaceuticals, including medications, vitamins, chemical molecules, and solvents.
Heterocyclic compounds such as Pyrido[2,3-d]pyrimidine are widely distributed in nature. It helps in the
development of various therapeutic agents. In this connection, nanotechnology provides a vast area for the synthesis
of these compounds. Therefore, chemists have focused on the synthesis of these derivatives using nanomaterials
due to their large surface-to-volume ratio and simple, effective, moderate conditions of utilization.
Tiny Dots, Big Impact: The Antimicrobial Power of Carbon Dots
Authors: Borgohain Ranadeep , Islam Md Moidul , Kaur Harpreet , Kaur Harmanjot , Kumar Amit , Raikwar Sarjana
Published: February 2025

Carbon Dots (CDs) are innovative nanoscale carbon-based materials rec-ognized for their exceptional optical properties, biocompatibility, and minimal tox-icity. These fluorescent nanoparticles, generally smaller than 10 nm, exhibit strong photoluminescence and absorption capabilities, which make them valuable for diverse applications in biomedicine, sensing, catalysis, and antibacterial technologies. Since their discovery in carbon soot in 2004, CDs have attracted attention for their environ-mental friendliness and versatile preparation methods, such as top-down (e.g., laser ablation, arc discharge) and bottom-up (e.g., hydrothermal treatment, microwave irra-diation) approaches. Functionalized with various surface groups, CDs offer excellent solubility and customizable properties for specific applications. One of the most prom-ising uses of CDs is as antibacterial agents, particularly against multidrug-resistant pathogens in the fight against bacterial infections. Their antibacterial mechanism in-volves generating Reactive Oxygen Species (ROS), which cause oxidative stress in bacterial cells, ultimately leading to cell death. Studies demonstrate the effective anti-bacterial action of CDs against bacteria such as E. coli and Staphylococcus aureus, attributed to ROS generation and membrane-penetrating effects. Despite challenges like synthesis consistency and potential toxicity, advancements in eco-friendly pro-duction and combination with other antimicrobial agents present exciting possibilities. CDs emerge as sustainable alternatives to traditional antibiotics, offering a valuable tool for advancing infection control in nanotechnology and global health contexts
Identification and Characterization of Biosurfactant-producing Novel Paenibacillus dendritiformis Strain ANSKLAB02 from Brackish River Water
Authors: Nayarisseri Anuraj , Bhrdwaj Anushka , Sharma Khushboo , Khan Arshiya , Singh Sanjeev Kumar
Published: February 2025

Introduction:

Biosurfactants are the surface-active reagents produced by microorgan-isms, which exhibit the non-toxic and augmented bioavailability potential for the decomposition of petro-based pollutants and performing microbial-enhanced oil recovery (MEOR).

Methods:

Thus, the present study entails the isolation of a novel biosurfactant-producing bacteria in MSM medium containing crude oil as a sole carbon source. Biosurfactant screening, cultural, and statistical optimization; Plackett - Burman Design, and response surface methodology (RSM) in conjunction with the Box-Behnken experimental design was employed for examining the bio-surfactant producing potential, and emulsification activity of the Paenibacillus strain, which ren-dered a maximum E24 index as 70%, with reduced surface tension of 29 mN/m.

Result:

The novel isolate was identified and named Paenibacillus dendritiformis strain AN-SKSLAB02 and the sequence was deposited in the NCBI-GenBank database with accession num-ber “KU518891”.

Conclusion:

The results signify that the bacterium holds the potential to burgeon in harsh condi-tions which is an appropriate habitat for application in MEOR, which has great potential to aid in environmental cleanup.
Lacticaseibacillus rhamnosus DTA 73 Exhibits Superior Anti-Adhesion Activity against Salmonella Typhimurium DTA 41 in Caco-2 cells
Authors: Rodrigues Silva do Carmo Matheus , Oliveira Alves Moreira de Carvalho Gabriella , Batista dos Santos Rodrigo , Fioravante Guerra André , da Silva de Azevedo Fortes Fabio , Luchese Rosa Helena
Published: February 2025

Background:

A challenge in choosing probiotic strains is to identify, in each one,
specific positive health effects to offer a tailored product. An important health claim of probiotics is
the competitive exclusion of pathogens and the consequent prevention and treatment of diarrhea.

Objective:

The aim of the study was to evaluate the ability of lactobacilli strains to adhere to intestinal
epithelial Caco-2 cells and to inhibit Salmonella adhesion in vitro and in situ.

Methods:

The ability to inhibit Salmonella biofilms by four strains of Lacticaseibacillus paracasei,
three strains of Lacticaseibacillus rhamnosus, two strains of Limosilactobacillus fermentum, and a
commercial strain of Lacticaseibacillus casei, was evaluated in vitro on hydrophobic polystyrene
surfaces and in situ using Caco-2 cells.

Results:

All strains showed a high adhesion capacity to Caco-2 cells, with no significant difference
between isolated strains and the commercial probiotic strain. In polystyrene surfaces, inhibition of
Salmonella biofilms by lactobacilli through the competition and exclusion mechanisms was significantly
more effective when compared to displacement. However, in Caco-2 cells, the isolates were
more effective in inhibiting Salmonella biofilms.

result:

All strains showed a high adhesion capacity to Caco-2 cells, with no significant difference between isolated strains and the commercial probiotic strain. In polystyrene surface, inhibition of Salmonella biofilms by lactobacilli through the competition and exclusion mechanisms was significantly more effective when compared to displacement. However, in Caco-2 cells the isolates were more effective in inhibiting Salmonella biofilms.

Conclusion:

It is concluded that hydrophobicity was not a good indicator of adhesion capability.
Although all lactobacilli strains have low cell surface hydrophobicity, they showed high adhesion
capacity in Caco-2 cells. The most promising strain, Lacticaseibacillus rhamnosus DTA 73, was
able to inhibit Salmonella adhesion in Caco-2 cells by competition, exclusion and displacement with
the same efficiency, suggesting that it could be effective not only in preventing but also in treating
diarrhea.
A Perspective Review on Animal Coronaviruses: From Infection Insights to Preventive Measures and Antiviral Advancements
Authors: - Tanvi , Goyal Rajat , Gautam Rupesh K. , Wilson Kashish , Garg Kajal , Sharma Tanmay , Gupta Sumeet , Singh Sachin Kumar , Ali Haider , Gupta Gaurav , Hussain Md Sadique
Published: February 2025

Animal coronaviruses (CoVs) have emerged as significant pathogens with considerable
implications for both animal and human health. This review provides an in-depth analysis of the
origins, transmission dynamics, and pathogenic mechanisms of animal CoVs. We examine the viral
entry, replication processes, and immune evasion strategies that enable CoVs to infect a variety of
host species. Additionally, the review highlights recent advancements in prevention and therapeutic
strategies, including the development of species-specific vaccines, enhanced biosecurity measures,
and surveillance systems aimed at controlling zoonotic spillover. Furthermore, we discuss the latest
antiviral strategies, including repurposed drugs, targeted molecular therapies, and the development of
novel antiviral agents. This review emphasizes the importance of interdisciplinary research in
advancing our understanding of animal CoVs and in developing effective interventions to mitigate
their impact on global health.
IPR and Blockchain Technology: Opportunities and Risks for the Digital Economy
Authors: Panda Brajesh Kumar , . Diksha , . Komal , Singh Amandeep
Published: February 2025

Blockchain technology is a decentralized, peer-to-peer network-based public, en-crypted, and immutable digital federated ledger system with various applications in the digi-tal economy. This paper examines how blockchain technology can strengthen intellectual property rights (IPR) in the digital age and the potential challenges and risks associated with this use. The paper analyses the advantages and disadvantages of blockchain technology for confirming and protecting IPR, such as transparency, security, efficiency, and scalability, as well as issues such as legal uncertainty, interoperability, and governance. The paper also ex-plores the implications of blockchain technology for different types of IPR, such as patents, and copyrights, and how it can facilitate innovation, licensing, and enforcement. The paper concludes by providing recommendations for improving the legal and regulatory framework for IPR management using blockchain technology and identifying some areas for further re-search.
Agomelatine Transdermal System Product Cycle: Development, Material/Process Screening, Optimization, Characterization, Delivery Mechanics
and Irritation study on Rat
Authors: Rathod Punitkumar , Lalwani Anita
Published: February 2025

Introduction/Objective:

Agomelatine (AGT) is used for the treatment of major depressive
disorder in adults. Agomelatine is highly susceptible to first-pass metabolism, and it has less
than 5% oral bioavailability. Therapy for major depressive disorder extends for a long period and
every time, additional caregivers are required to remind and manage the timely dosing of oral medicine
to patients. In such cases, once a week, administration of agomelatine via transdermal patch
dosage form provides major patient benefits and lowers overall therapy costs.

Methods:

An agomelatine transdermal patch was prepared using the solvent evaporation method
using the LTE-S Werner Mathis AG coater and dryer. A patch was prepared using silicon adhesive
after screening different pressure-sensitive adhesives like acrylate, polyisobutylene, and silicon. To
make a crystal-free patch, the concentration of povidone k-29/32 was optimized in preliminary trials.
To deliver the drug over a 7-day period, propylene glycol monolaurate (PGML) was identified
from different penetration enhancers. Three factors optimization was carried out, like the concentration
of povidone k-29/32, the concentration of PGML, and the mixing time of the blend using the
Box Behnken design. 3D surface response curves and contour plots were derived using Design Expert
and Minitab software. From overlay plots, design spaces were identified.

Result:

The optimized AGT patch has good adhesion properties along with a desirable flux of 4.63
μg/cm2/h on human cadaver skin along with a lower residual drug. There was no impact of heat flux
studies on normal conditions, hence justifying the in-use condition of the patient population during
hot showers, baths, and saunas. AGT Patch was also non-irritating in skin irritation studies performed
on Wistar albino rats.

Conclusion:

It was concluded that agomelatine transdermal patches can be manufactured using silicon
adhesive, povidone k-29/32, and propylene glycol monolaurate for the treatment of major depressive
disorder and will be the most convenient and cost-effective therapy for the patient.
Workforce Diversity as a Driver of Employee Performance: Perspectives from Institutions of Higher Education
Authors: Umme Ara  , Sarika Sushil
Published: February 2025

The study analyzes the role of workforce diversity in shaping employee performance. within higher education settings, emphasizing gender diversity (GD), age diversity (AD), and experience diversity (ED). The research is grounded on a quantitative approach, utilizing a standardized survey that was given to administrative and academic staff in higher education institutions in Allahabad. The study employed regression analysis to analyse the association among considered diversity variables and employee performance (EP). The findings reveal that all three aspects of diversity dimensions significantly influence employee performance, with the regression model yielding the equation EP = 1.885 + 1.840 GD + 1.291 AD + 2.348 ED. This suggests that gender diversity, age diversity, and experience diversity positively contribute to enhancing employee performance, with experience diversity having the most substantial effect. The findings underscore the significance of cultivating a workforce with diversity to improve organisational outcomes in the higher education sector. This study contributes to the growing corpus of research on workforce diversity and the influence it has on for employee performance, providing insightful information to institutional leaders and legislators who want to establish inclusive and productive workplaces
Strategies for Success in Aerospace: The Innovative and Disruptive Power of Reusable Rockets
Authors: Ishita Prakash  , Niraj Pandey
Published: February 2025

Rocket reusability will be a revolution in the aerospace industry, compelling new models of fabrication of launch vehiclesand outer-space exploration. This paper explores the transformative nature of reusable rocket technology as innovational,cost-cutting, and sustainable. A reusable rocket can be launched multiple times without necessitating the use of a differentrocket. The cost has come down to the kilogram when it goes into space. Companies like Space-X and Blue Origin havebrought this within the range carried by such rockets. Such research is also taken to a deeper level to look into the widerdisruption caused by these technologies at the governmental and private levels, new opportunities through satellitedeployment, space tourism, and interplanetary missions. Strategic approaches followed by aerospace companies areinnovation with iterative testing for cost optimizations. Results focused on demonstrating potential for inside-outinnovation to achieve space or economic feasibility, making the space accessible for human beings. As such, strategicmodels in this research may also be applied in other sectors of high-tech industries as they look to break through into newinnovations
Innovation in Financial Services: Disrupting Traditional Banking with Fintech
Authors: Srishti Chandel
Published: February 2025

Fintech's explosive expansion has drastically changed the global financial scene, especially by upending establishedbanking structures. The paper addresses the primary forces driving the emergence of fintech, how it is changing traditionalbanking procedures, and the tactics used by well-established financial institutions to stay competitive. Fintech innovationsare growing in popularity among consumers because of their user-friendly, easily available, and effective financial services.The findings reflect that fintech technologies, including robo-advisors, peer-to-peer lending, digital wallets, and rapidpayments, are revolutionizing the banking business. Fintech's growth is being driven by advances in digital technology,changing client demands, and regulatory support. Traditional banks are investing in digital technologies, establishinginnovation centers, and incorporating cutting-edge technology into their offerings. They are also stepping up cybersecurityand advocating for regulatory changes to equalize the playing field with fintech disruptors.
Instagram as a Tool to Improve Human Histology Learning in Medical Education: Descriptive Study
Authors: Escamilla-Sanchez Alejandro , López-Villodres Juan Antonio , Alba-Tercedor Carmen , Ortega-Jiménez María Victoria , Rius-Díaz Francisca , Sanchez-Varo Raquel , Bermúdez Diego
Published: February 2025

Background

Student development is currently taking place in an environment governed by new technologies and social media. Some platforms, such as Instagram or X (previously known as “Twitter”), have been incorporated as additional tools for teaching and learning processes in higher education, especially in the framework of image-based applied disciplines, including radiology and pathology. Nevertheless, the role of social media in the teaching of core subjects such as histology has hardly been studied, and there are very few reports on this issue.

Objective

The aim of this work was to investigate the impact of implementing social media on the ability to learn human histology. For this purpose, a set of voluntary e-learning activities was shared on Instagram as a complement to traditional face-to-face teaching.

Methods

The proposal included questionnaires based on multiple-choice questions, descriptions of histological images, and schematic diagrams about the subject content. These activities were posted on an Instagram account only accessible by second-year medical students from the University of Malaga. In addition, students could share their own images taken during the laboratory practice and interact with their peers.

Results

Of the students enrolled in Human Histology 2, 85.6% (143/167) agreed to participate in the platform. Most of the students valued the initiative positively and considered it an adequate instrument to improve their final marks. Specifically, 68.5% (98/143) of the student body regarded the multiple-choice questions and image-based questions as the most useful activities. Interestingly, there were statistically significant differences between the marks on the final exam (without considering other evaluation activities) for students who participated in the activity compared with those who did not or barely participated in the activity (P<.001). There were no significant differences by degree of participation between the more active groups.

Conclusions

These results provide evidence that incorporating social media may be considered a useful, easy, and accessible tool to improve the learning of human histology in the context of medical degrees.
Instagram Posts Promoting Colorectal Cancer Awareness: Content Analysis of Themes and Engagement During Colorectal Cancer Awareness Month
Authors: Srivastava Aditi , Stimpson Jim P
Published: February 2025

Background

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide, with early detection and screening being critical for reducing mortality. Social media platforms like Instagram offer a unique opportunity to raise awareness about CRC, particularly during designated awareness months. However, there is limited research on the effectiveness of CRC-related content on Instagram.

Objective

This study aims to examine how Instagram is used to raise awareness about CRC during Colorectal Cancer Awareness Month by analyzing the thematic content and engagement metrics of related posts. The research seeks to identify the prevalent themes, assess audience interaction with these messages, and highlight areas for improvement in leveraging Instagram as a tool for cancer awareness campaigns.

Methods

A total of 150 Instagram posts were collected based on their use of specific hashtags related to CRC awareness (#colorectalcancer, #colorectalcancerawareness, #colorectalcancerawarenessmonth) during March 2024. The text and images in the posts were categorized into themes such as screening and early detection, symptoms, general awareness, risk factors, individual’s experiences, representation of racial and ethnic minoritized communities, and representation of women. Engagement metrics, including the number of likes and comments, were also analyzed. Two researchers independently coded the posts, achieving high interrater reliability (Cohen κ=0.93).

Results

Organizational accounts were more active, contributing 82% (n=123) of the 150 posts, compared to 18% (n=27) from individual users. The most frequently mentioned theme was screening and early detection, which made up 37.3% (n=56) of all posts. General awareness came in second at 19.3% (n=29), and risk factors came in third at 12% (n=18). Posts about individual experiences and general awareness received the highest engagement, indicating the effectiveness of personal narratives and broad informational content. Themes related to symptoms and representation of racial and ethnic minoritized communities and women were underrepresented.

Conclusions

This study highlights the potential of Instagram as a platform for promoting CRC awareness, particularly through posts about screening and early detection and personal experiences. However, there is a need for more inclusive and diverse content to ensure a broader reach and impact.
Protocol for the 24MOVE Study: a Prospective Cohort Study Measuring 24-Hour Movement Profiles During Pregnancy (Preprint)
Authors: Ryan Elizabeth , Asera Alex , Gabriel Kelley Pettee , Manber Rachel , Quesenberry Charles P , Avalos Lyndsay A , Hedderson Monique M , Badon Sylvia E
Published: February 2025

BACKGROUND

Physical activity (PA) and sleep during pregnancy may mitigate the increased risk for adverse pregnancy outcomes posed by gestational diabetes and high gestational weight gain in pregnant individuals with pre-pregnancy overweight and obesity. Recent studies have conceptualized PA, sedentary behavior, and sleep as part of a 24-hour movement framework; however, there is a gap in knowledge about the relationship between 24-hour movement and pregnancy outcomes.

OBJECTIVE

This paper describes the study protocol for the 24MOVE study, a prospective cohort study that examines associations between 24-hour movement profiles across pregnancy and maternal glucose tolerance, gestational weight gain, and infant birthweight.

METHODS

Participants (n=306) were recruited from a large, integrated health care delivery system at 10 weeks gestation. In early (10-12 weeks), mid (20-22 weeks), and late (33-35 weeks) pregnancy, all eligible individuals with a pre-pregnancy BMI of ≥25 kg/m2 completed online surveys collecting information on sociodemographic characteristics and pregnancy symptoms and behaviors, including sleep quality. Participants concurrently wore a research-grade accelerometer for 24 hours per day for 7 consecutive days to capture movement, sedentary behavior, and sleep data. Data from accelerometry will be processed to create 24-hour movement profiles. Pregnancy outcomes will be ascertained from the electronic health record. We will use compositional data analysis methods, modeling associations of reallocations of time from one component behavior to another at various timepoints with outcomes.

RESULTS

Over an 18-month recruitment period, 2,035 individuals were invited to participate and of those, 306 eligible participants enrolled in this study. The enrolled cohort had a median age of 33 years and BMI of 28.8 kg/m². Most participants had private insurance (87%) and were multiparous (76%). Follow-up data collection is ongoing.

CONCLUSIONS

The 24MOVE Study is designed to address gaps in our knowledge of the impact of 24-hour movement during pregnancy on maternal glucose metabolism, gestational weight gain, and other risk factors for childhood obesity, such as high birthweight. Data from this study will also serve as a rich resource for future investigations of 24-hour movement profiles and behavior substitutions and other perinatal mental and physical health outcomes.
Teacher’s Autonomy Support Role in University Psychology Class Teaching Quality
Authors: Liu Dingqiao
Published: February 2025

This research investigates the relationship between the autonomy support afforded to teachers and class teaching. The profile of respondents includes a diverse group of teachers varying in sex, years of service, and highest educational attainment. Teachers' perceptions of autonomy support were generally positive, particularly in areas such as responsive teaching and providing rationale, although there is room for improvement in minimizing control and pressure. No significant differences were found in the perceived autonomy support based on sex, length of service, or educational attainment. The correlation analysis shows a nuanced relationship between autonomy support and class teaching.The research concludes that while overall teacher’s autonomy support do not significantly correlate with general class teaching, specific practices can influence certain dimensions of class teaching. Recommendations include improving communication, fostering a supportive environment, increasing opportunities for teacher autonomy, and providing clear rationales for decisions. These insights aim to enhance teacher’s class autonomy and contribute to creating a more effective educational environment for university students.
Efecto citotóxico de nanopartículas de MgO y ZnO en cultivo con células de cáncer oral: nanoacarreadores para tratamientos quimioterapéuticos
Authors: Flores-Ramírez Valeria Estefanía , Aranda-Herrera Benjamín , Guzmán-Rocha Dulce , García-Contreras René
Published: February 2025

El cáncer oral, una de las principales causas de mortalidad a nivel mundial, se trata comúnmente con quimiorradioterapia. No obstante, estas terapias tienen limitaciones. Investigaciones recientes se enfocan en el uso de nanopartículas (NPs) como MgO y ZnO para mejorar el tratamiento. Y, para evaluar el efecto citotóxico de NPs de MgO y ZnO en células cancerígenas de origen linfoblástico, se utilizaron células cancerígenas de cultivo primario de origen linfoblástico caracterizadas por inmunohistoquímica (HIC) y se realizaron pruebas de citotoxicidad utilizando NPs de MgO y ZnO en concentraciones de 0 a 1.33 mg/mL. La viabilidad celular se midió mediante el ensayo MTT por UV-Vis. El análisis estadístico fue mediante la prueba de t-student y ANOVA (p ≤ 0.05). Los análisis histopatológicos confirmaron la presencia de lesiones neoplásicas linfoblásticas orales con características específicas, positivo a ciclina D1 y negativo a CD3. Los resultados mostraron ligera toxicidad a la máxima dosis para ambas NPs (80% MgO y 94% ZnO) reducción estadísticamente significativa (p < 0.05) dosis-dependiente. Las NPs de MgO y ZnO tienen un ligero efecto citotóxico en células cancerosas linfoblásticas, por lo cual es necesario desarrollar tratamientos quimioterapéuticos más efectivos basados en nanopartículas en combinación con agentes antitumorales para confirmar esta hipótesis.
WOMEN’S SUFFRAGE IN MEXICO AS A CASE OF CONSTITUTIONAL DISMEMBERMENT DURING AUTHORITARIANISM
Authors: Pineda Acevedo Mtro. Humberto
Published: February 2025

El objetivo primordial de este artículo consiste en identificar a la reforma del presidente Adolfo Ruiz Cortines que reconoció la ciudadanía a las mujeres mexicanas como una modificación profunda en la Constitución Mexicana, la cual pudo haber representado un tipo de desmembramiento constitucional de acuerdo con las condiciones políticas del régimen autoritario.
LAS REDES SOCIALES COMO RED DE APOYO EN LA MEDIACIÓN PENAL CON UN ENFOQUE DE GÉNERO EN LA SOLUCIÓN DE CONTROVERSIAS EN MÉXICO
Authors: Hernández Mendoza Dra. Liliana
Published: February 2025

La mediación penal es un mecanismo de justicia restaurativa que fomenta el diálogo entre las partes para resolver conflictos sin recurrir al encarcelamiento. En México, las mujeres privadas de libertad enfrentan condiciones marcadas por desigualdades estructurales, como violencia de género, pobreza y discriminación. Muchas de estas mujeres se encuentran en prisión preventiva sin sentencia, enfrentando un proceso judicial prolongado y con una falta de defensa adecuada.
Un enfoque de género en la mediación penal fortalecería el reconocimiento de estas desigualdades y permitiría abordar las necesidades específicas de las mujeres, promoviendo soluciones equitativas y su reintegración social. Las redes sociales especializadas, como el canal “Penitencia” y la organización Reinserta, visibilizan estas problemáticas, generan apoyo y difunden información clave sobre mediación penal. Además, estas plataformas pueden influir en políticas públicas, para impulsar una justicia más inclusiva y humana que atienda las realidades de las mujeres en prisión.
Rendimiento de forraje y valor nutritivo del ensilado de forrajes alternativos y tradicionales de otoño-invierno
Authors: Lopez-Jara Anabel G. , Reta-Sánchez David G. , Santana Omar I. , Reyes-González Arturo , Rodríguez Hernández Karla , Granados-Niño Jorge A. , López-Calderón Magaly J. , Sánchez-Duarte Juan I.
Published: February 2025

El objetivo fue evaluar el rendimiento de forraje y el valor nutritivo del ensilado de forrajes alternativos y tradicionales. Se evaluó el efecto de la especie sobre el rendimiento de materia seca (MS), la fermentación (pH y N-amoniacal [NH3-NT]) y el valor nutritivo (proteína cruda [PC], fibra neutro detergente [FDN], carbohidratos no fibrosos [CNF]); calidad nutricional (total de nutrientes digestibles [TND]); valor nutritivo (energía neta de lactancia [ENL], la digestibilidad in situ de la MS [DMS] y la FDN [DFDN]) de los ensilados. La avena tuvo el mayor rendimiento de MS (9,784 kg ha-1) y cártamo el más bajo (6,998 kg ha-1), pero no hubo diferencias entre canola (8,937 kg ha-1), remolacha (8,828 kg ha-1), cebada (9,784 kg ha-1) y triticale (9,355 kg ha-1). La fermentación indicó un pH similar entre los ensilados evaluados, pero el NH3-NT fue superior en los ensilados de remolacha y cártamo que en los otros ensilados. La PC fue superior en los ensilados de canola, remolacha y cártamo (17.8 a 19.5%) que en los de avena, cebada y triticale (13.7 a 15.0 %; P<0.0001), pero la FDN fue superior en los últimos (49.7 a 53.4 %; P<0.0001). El ensilado de canola tuvo más CNF, TND y ENL y solo el ensilado de remolacha pudo igualarlo. La DMS fue superior en los ensilados de canola (80.52 %) y remolacha (84.55 %) que en los de avena (62.24 %), cebada (58.90 %) y triticale (62.79 %; P<0.0001). Sin embargo, la DFDN fue similar entre todos los ensilados.
Efecto de Moringa oleifera en pruebas de fermentación ruminal in vitro y su repercusión en gases de efecto invernadero
Authors: Gómez-Chávez Jorge Andrés , Castillo-Castillo Yamicela , Castillo-Rangel Francisco , Domínguez-Viveros Joel , Ordóñez Baquera Perla Lucía
Published: February 2025

El ambiente ruminal se ha manipulado biotecnológicamente para mejorar la productividad animal y recientemente se buscan alternativas naturales, saludables y ecológicas para este fin. Se ha probado Moringa oleifera como alimento para el ganado porque sus hojas son ricas en minerales, proteína y metabolitos secundarios. El objetivo fue evaluar los cambios en la actividad ruminal por la presencia de M. oleifera. Se probaron tres tratamientos; TT (testigo 100% alfalfa), MB (15% Moringa-85% alfalfa) y MA (30% Moringa-70% alfalfa). El experimento se realizó in vitro con líquido ruminal ovino. Para pH y nitrógeno amoniacal (N-NH3) no se observaron diferencias (P>0.05). La digestibilidad de la materia seca fue diferente (P<0.05) entre tratamientos. La producción de gas mostró diferencias (P<0.05) entre tratamientos. Para la concentración de ácidos grasos volátiles (AGV) se observaron diferencias (P<0.05). El CO2 y CH4 fueron diferentes entre tratamientos (P<0.05), siendo MB el menor para ambas variables. Se concluye que adicionar moringa a una ración de alfalfa no tiene efecto sobre el pH y N-NH3, sin embargo, aumenta la digestibilidad de la materia seca, pero disminuye la concentración de AGV y la digestibilidad de fibras. Además, incluir 15 % de moringa a una ración de alfalfa puede reducir la producción de gases de efecto invernadero. Se recomienda seguir evaluando esta alternativa para la alimentación animal.
Comparación de métodos de aprendizaje automático para predicción de valores de cría genómicos en características de crecimiento en bovinos Suizo Europeo
Authors: Vélez Labrada José Luis , Pérez Rodríguez Paulino , Nilforooshan Mohammad Ali , Ruíz Flores Agustin
Published: February 2025

Los algoritmos de Aprendizaje Automático (AA) han demostrado ventaja al abordar desafíos asociados con la cantidad y la complejidad de la información, permiten descubrir patrones, realizar análisis eficientes y servir como herramienta para la toma de decisiones. Este estudio, tuvo como objetivo comparar cuatro métodos de AA: redes neuronales artificiales (RN), árboles de regresión (AR), bosques aleatorios (BA) y máquina de soporte vectorial (SVM) para predecir el valor genómico en bovinos Suizo Europeo utilizando registros fenotípicos de pesos al nacimiento (PN), destete (PD) y al año (PA), así como información genómica. Los resultados indican que la capacidad predictiva de los modelos varía según la característica y la cantidad de información disponible. En general, RN, BA y SVM mostraron un desempeño similar, mientras que AR tuvo un desempeño inferior. La metodología SVM destacó como la herramienta con mayor potencial, obteniendo los valores más altos de correlación Pearson entre fenotipos corregidos y valores genéticos predichos para PD. A pesar de un mayor costo computacional, RN tuvo un desempeño razonable, especialmente para PN y PA. La selección del modelo final depende de las necesidades particulares de la aplicación, así como de factores prácticos como la disponibilidad de datos, recursos computacionales y la interpretabilidad; pero en general, RN y SVM surgieron como opciones sólidas en varias categorías.
Optimización de la predicción del valor de reproducción en ganado Braunvieh por medio del análisis multirasgo de rasgos de crecimiento
Authors: Nilforooshan Mohammad Ali , Ruíz-Flores Agustín , Pérez-Rodríguez Paulino , Pabiou Thierry , Saavedra-Jiménez Luis Antonio , Valerio-Hernández Jonathan Emanuel
Published: February 2025

Actualmente, la evaluación genética de los rasgos de crecimiento (peso al nacer - PN, peso al destete - PD y peso al año - PA) en el ganado Braunvieh en México se lleva a cabo por medio de modelos univariados para el PN y bivariados para el PD y PA. La precisión de las evaluaciones genéticas se puede mejorar mediante un modelo trivariado. Se analizó tanto el sesgo en las evaluaciones univariadas y bivariadas causado por los rasgos faltantes en el análisis, como el aumento en la precisión producido por el análisis trivariado. Los datos de pedigrí y de rendimiento se obtuvieron de la Asociación Mexicana de Criadores de Ganado Suizo de Registro. Después de editar los datos, se realizaron análisis univariados, bivariados y trivariados y se hicieron comparaciones entre ellos. Se empleó una estrategia simple de reducción del conjunto de datos, reduciendo notablemente la cantidad de datos en los análisis. Los animales excluidos de los análisis se evaluaron a partir de las soluciones de los animales incluidos en los análisis, lo cual requirió mucho menos poder de computación. El análisis bivariado mostró evaluaciones sesgadas del PD y PA y de las tendencias genéticas. Las tendencias genéticas se subestimaron en los animales jóvenes. Desde mediados de la década de 1990, todos los rasgos mostraron una ganancia genética constante. El sesgo se debió a la preselección natural/artificial para PN. La inclusión del PN en el análisis trivariado ayudó a tomar en cuenta la información de preselección. La evaluación univariada del PN y la tendencia genética fueron imparciales. También, el PN aumentó menos en precisión a partir del PD y PA que el PD y PA a partir del PN. Se recomienda el análisis trivariado de los rasgos con una reducción del conjunto de datos para reducir el poder computacional requerido para procesar los datos.
Konsep Diri Pada Remaja Putus Sekolah Dari Keluarga Prasejahtera Di Desa Beji
Authors: Yudi Diah Titi Nawang , Khotimah Khusnul
Published: February 2025

Masa remaja seringkali dianggap sebagai masa paling krusial dalam hidup seseorang, masa remaja bukan hanya sebagai transisi antara masa anak-anak menuju dewasa. Namun, pada masara remaja seseorang sedang dalam proses pencarian jati diri. Mereka yang berada dalam fase remaja cenderung memiliki semangat dan motivasi yang tinggi untuk mencoba banyak hal. Maka tak heran ketika masa remaja seseorang terlihat tidak memiliki rasa takut dan beban saat mencoba hal baru. Perbedaan sikap dan pandangan atau konsep diri yang dimiliki remaja antar satu sama lain tetunya berbeda, hal ini dipengaruhi lingkungan, tingkat emosi dan juga pendidikan. Penelitian ini bertujuan untuk meneliti bagaimana konsep diri yang dimiliki remaja putus sekolah. Berbgai data diperoleh melalui observasi, wawancara maupun dokumentasi dengan pendekatan kualitatif-fenomenologi. Setelah dilakukan penelitian pada tiga (3) subjek yang dipilih diperoleh hasil bahwa pada saat remaja pertama kali putus sekolah mereka memiliki perasaan pesimis dan seperti tidak memiliki arah tujuan. Namun, seiring berjalannya waktu mereka mampu memikirkan jalan keluar sehingga konsep diri positif lebih dominan disbanding konsep diri negatif.
KONTROL DIRI DALAM PERSPEKTIF ISLAM DAN UPAYA PENINGKATANNYA MELALUI LAYANAN BIMBINGAN KONSELING ISLAM
Authors: S Mansyur
Published: February 2025

This study seeks to provide a conceptual framework about self-control in an Islamic perspective and efforts to improve it through Islamic counseling and guidance services. This research is library research with descriptive type, the data collection is taken from various books and journals related to the theme and discussion. The results showed that self-control in Islam is a person's ability to direct his attitude and behavior based on faith and piety to Allah SWT. Efforts that can be made in increasing self-control are to provide Islamic counseling guidance services through individual counseling services using a Sufistic approach (takhalli, tahalli, and tajalli).
Generasi Alpha: Tantangan dan Kesiapan Guru Bimbingan Konseling dalam Menghadapinya
Authors: Anwar Faisal
Published: February 2025

The alpha generation is the generation born from 2010-2025. This generation has parents from generations Y and Z. They were born at the same time as the rapid pace of technological development where information technology can be said to be perfect. In contrast to generations Y and Z where information technology technology is still in transition. The alpha generation cannot be separated from gadgets. Their proximity to gadgets has an effect on lifestyle, mindset, way of learning, and even health. This is a concern for many parents. This study aims to describe the character of children who were born as an alpha generation and the readiness of counseling teachers must prepare in dealing with them. The research method in this study is library research with qualitative techniques. The results of a study conducted from several reviewed articles. Guidance and counseling teachers must be creative in providing services to their students. They must also be technology literate in providing services. That's because the children of the alpha generation cannot be separated from gadgets.
PURNABAKTI DALAM PERSPEKTIF KONSELING ISLAM
Authors: Jamil Yusuf M.
Published: February 2025

Setiap orang yang bekerja sebagai Aparatur Sipil Negara, karyawan dan pekerja sesuai peraturan perundangan yang berlaku wajib menerima pada purna bakti atau pensiun dengan segala hak yang melekat padanya. Memasuki masa pensiun berarti mengakhiri masa bertugas/bekerja dan kembali menjadi warga masyarakat biasa untuk meneruskan pengabdiannya kepada keluarga dan kegiatan-kegiatan sosial masyarakat. Pada sebagian pensiunan bahwa memasuki masa purna bakti adalah sebuah kebahagiaan, namun pada sebagian lainnya bisa mengalami masalah-masalah berat seperti berkurangnya keuangan, menurunnya kesehatan, merasa kesepian dan sebagainya. Pada sebagian pensiunan yang mengalami masalah sangat mungkin yang bersangkutan dapat menangani sendiri masalahnya, namun pada sebagian lainnya dipandang perlu mendapat layanan bantuan, termasuk layanan konseling Islam. Dalam perspektif konseling Islam adalah beberapa hal yang ditawarkan, yakni: (1) memunculkan asumsi bahwa para pensiunan itu haus akan kasih sayang dan penerimaan anggota keluarga. Lalu konseling Islam harus mengakomudir dua hal ini serta  mengembangkan tujuan hidup yang bermakna; (2)  sebagai konselor Muslim harus mengedepankan banyak mendengar tentang masalah dan konsep hidup bermakna yang didambakan klien di hari-hari tuanya hingga menemukan kesepakatan yang bermakna; dan (3) indikator kualitas diri seseorang klien amat ditentukan oleh kualitas ketabahan dan kesabaran. Semakin tangguh seseorang menghadapi masalah, maka semakin kuat dalam mengharungi kesulitan-kesulitan hidup di hari tuanya.
MANAJEMEN EMPATI KONSELOR (Analisis Problematika Koselor dalam Menghadapi Emosi Negatif Klien)
Authors: NK Mahdi
Published: February 2025

Empati adalah suatu keterampilan konselor yang mampu merasakan kondisi emosional kliennya, sehingga bisa membina relationship yang akrab baik secara kognitif maupun afektif. Dalam praktiknya, terdapat kontradiksi terkait empati. Terutama saat konselor mengahadapi klien sedang meluapkan emosi negatifnya. Konselor dituntut untuk turut merasakan apa yang dirasakan kliennya sebagai wujud empatinya. Namun, di sisi lain konselor juga tidak mungkin menunjukkan perilaku yang merefleksikan pertimbangan untuk tidak mementingkan diri sendiri demi kebaikan orang lain dengan cara larut ke dalam emosi negatifnya klien. Kondisi seperti inilah yang harus dibedakan antara efektivitas penggunaan empatinya. Atas dasar asumsi tersebut, tulisan ini bermaksud untuk membedakan penggunaan empati yang efektif konselor saat menghadapi emosi negatif klien, dan bagaimana dalam proses layanan konseling.