bluuebunny/crossref_metadata_2025 huggingface dataset:
MRI-phenotype of kidney structural changes in patients with resistant hypertension: correlations with functional markers
Authors: Ryumshina N. I. , Zyubanova I. V. , Falkovskaya A. Yu. , Gusakova A. M. , Ussov V. Yu. , Zavadovsky K. V.
Published: September 2023

The aim: to determine the phenotype of kidney damage characteristic of resistant arterial hypertension by MRI, including the volume of renal parenchyma, and its association with biomarkers of renal dysfunction.

Patients and methods. The main group included 35 patients with resistant arterial hypertension (RAH), average age 57.6±8.4 years. The comparison group consisted of 20 men and women without cardiovascular pathology, comparable in gender and age. To determine the qualitative and quantitative changes in the kidneys, MRI was performed (1.5 Tesla, Titan vantage, Toshiba). Kidney volumes (TKV, TCV) were calculated using the ellipsoid formula. Kidney volumes indexed for height, BMI and body surface area were calculated. Renal dysfunction was assessed by the level of serum creatinine and cystatin C, as well as by the value of eGFR (CKD-EPI).

Results. The MR phenotype of kidney changes in resistant hypertension is described – renal cortex surface roughness, renal cortex thinning, decreased kidney sizes, and rounded kidney shape. The relationship of the renal parenchyma volume indexed for height with the level of cystatin C (r=-0.36), creatinine (r=-0.48) and eGFR (r=0.49) was revealed.

Conclusion. The hypertensive renal MRI-phenotype includes a decreased in kidney size, thinning of the renal cortex, renal cortex surface roughness and rounded shape of the kidneys. The total volume of the renal cortex indexed for height has a close relationship with serum biomarkers of renal dysfunction, and is recommended for use as a non-invasive marker reflecting the state of the kidneys in resistant arterial hypertension.
Ketamina no manejo da dor aguda: uma revisão integrativa
Authors: Leocovick Luã , Bubans Amanda Battu , Bernardes Laércio , Bohnen Lilian Caroline , Zancanaro Mayra
Published: September 2023

O mecanismo de ação da ketamina é antagonizar os receptores NMDA (N-metil-D-aspartato) com potencial analgésico e sedativo. Introduzida na prática clínica há cerca de 30 anos, atuando como droga monoanestésica. Nos últimos anos surgiram indicações para o uso da ketamina, com descobertas de colocações clínicas, incluindo controle da dor e uso na psiquiatria. A principal motivação para estudar o uso da ketamina decorreu da possibilidade de tornar a droga uma opção no tratamento da dor, visto que as drogas mais utilizadas, os opióides, podem causar complicações e dependência. O objetivo é analisar como a literatura científica nacional e internacional descreve a utilização da ketamina no manejo da dor aguda. Trata-se de uma revisão integrativa da literatura com abordagem qualitativa, realizada de acordo com as seis etapas recomendadas por Ganong. O levantamento bibliográfico foi realizado em busca online nas bases disponíveis na Biblioteca Virtual em Saúde (BVS), e nas bases de dados Scientific Eletronic Library Online (SciELO), PubMed e Embase. Com base nos Descritores em Ciências da Saúde (DeCS/MeSH), foram utilizados nas bases selecionadas os descritores em português ketamina e dor aguda, e em inglês ketamine e acute pain. Para os resultados os artigos selecionados para esta pesquisa foram analisados no formato completo, tipo ensaio clínico e agrupados em categorias “uso da ketamina na emergência”, “utilização da ketamina na dor pós-operatória” e “utilização da ketamina nas diversas patologias que apresentam dor aguda”. Para análise crítica e discussão, 15 artigos compuseram os resultados do estudo. Conclui-se que a Ketamina é um eficaz adjuvante, pois prolonga a duração de outros fármacos no manejo de dor aguda na emergência, tem potencial de analgesia, redução de doses e efeitos colaterais de opioides, seu uso perioperatório deve ser considerado e a utilização em baixas doses apresenta perspectivas promissoras em analgesia pós-operatória.
MONITORAMENTO DO ESTADO NUTRICIONAL DE GESTANTES ADOLESCENTES DA REGIÃO NORDESTE: ANÁLISE DE DADOS DO SISVAN
Authors: Costa Larissa Silva Gradil , Pereira Victor Guilherme , Sousa Dara Cristina da Silva de , Andrade Gleice Elem Ramos Pimentel , Silva Silvania Bispo da , Santos Valdelice Ribeiro Barbosa , Weirich Laís Canevese , Feijão Lucas Evangelista Alves , Petri Alaiane Cristina , Folly Lais Kazmierski
Published: September 2023

A gravidez na adolescência constitui um problema de saúde pública em função das consequências biológicas, psicológicas, econômicas e familiares, que podem afetar os indicadores socioeconômicos do país, principalmente por ocorrer de forma precoce e não planejada. São diversos os fatores que levam a uma gravidez nesta fase da vida, dentre eles, a baixa escolaridade, aspectos socioeconômicos, redução da faixa etária da menarca e da primeira relação sexual e a falta de informações sobre os métodos contraceptivos. Trata-se de um estudo epidemiológico, descritivo, ecológico e quantitativo, desenvolvido através de dados secundários das gestantes adolescentes beneficiárias do Programa Bolsa Família no ano de 2022. Os dados foram extraídos de relatórios públicos do Sistema de Vigilância Alimentar e Nutricional (SISVAN) do Departamento de Informação no Sistema Único de Saúde (DATASUS). Para a geração dos relatórios foi agrupado os estados da região Nordeste, as variáveis fase da vida “gestante” e idade “adolescente”, para o sistema de origem dos dados “sistema de gestão do Bolsa Família – DATASUS”. Foram analisados dados de 240.769 gestantes adolescentes referentes ao período de 2019 a 2022 nos nove estados da região Nordeste. O ano de 2022 apresentou o maior número de gestantes acompanhadas (n=71.848). Houve predominância de peso adequado em todo o período analisado (40,7%), seguido da classificação de baixo peso (32,05%) e excesso de peso (27,1%). A Paraíba apresenta maior prevalência de baixo peso com 44%. O Maranhão apresenta maior percentual de gestantes com peso eutrófico (43,6%). O Rio Grande do Norte possui maior número de gestantes acima do peso 32,8% (n=3.488). Apesar da prevalência de peso adequado, os resultados obtidos nesta pesquisa, chamam atenção para elevada taxa de baixo peso na região Nordeste, principalmente nos estados da Paraíba e Maranhão. A orientação dietética na manutenção do estado nutricional torna-se eficaz em intervir em situações de risco, como a desnutrição e o excesso de peso, principalmente em casos de gravidez na adolescência.
AMBIENTES ALCOGÊNICOS E JUVENTUDE
Authors: Vilela Junior Guanis de Barros , Benedetti Graciela Balestrin , Rasul Carolina Nazif , Soares Thiago Felix , Infante Marcus Vinicius , Mantovani Isabelly Simon , Teixeira Laiane Reis , Lebkuchen Paula Fernanda Barbeto Pimenta , Hamud Ana Paula Barancelli , Melo Francisco Collins Neves de , Chinaia Nayara Saad , Silio Luís Felipe , Passos Ricardo Pablo
Published: September 2023

Introdução: a indústria de bebidas alcoólicas cresce mundialmente, um claro sinal de um aumento da demanda mercadológica. Nesse contexto, os chamados ambientes alcogênicos são os principais responsáveis pelo aumento dessa demanda, especialmente junto aos jovens (adolescentes inclusos), alvos preferenciais de um marketing ostensivo, com especial direcionamento às jovens mulheres. Objetivo: realizar uma revisão narrativa para refletir sobre a influência de ambientes alcogênicos no consumo abusivo de bebidas alcoólicas por jovens, pontuando intencionalmente, pesquisas realizadas em países ricos e pobres. Métodos: foi realizada busca com as palavras-chave em inglês: alcohol, Youth e alcoogenic environment, publicados no período de 2021 a 2023. Após os critérios de seleção restaram 13 artigos presentes nessa revisão. Resultados: Ficou patente a influência de ambientes alcogênicos e a aderência de jovens ao consumo abusivo de bebidas alcoólicas. É importante esclarecer que ambiente alcogênico também inclui o exemplo dos pais e a disponibilidade de bebidas alcóolicas, inclusive no espaço familiar. Outra evidência é a quebra do discurso recorrente de que jovens aprendem a beber na universidade, isso acontece muito antes deles chegarem até a universidade, sendo que para a maioria deles, chegar à universidade não passa de um sonho distante.
Keberlakukan Ketentuan Pasal 3 Ayat (1) Peraturan Menteri Keuangan Republik Indonesia Nomor 16/PMK.03/2010
Authors: Mantovani Reda
Published: September 2023

Abstrak
Menurut Peraturan Menteri Keuangan Republik Indonesia Nomor 16/PMK.03/2010 Tentang Tata
Cara Pemotongan Pajak Penghasilan Pasal 21 Atas Penghasilan Berupa Uang Pesangon, Uang
Manfaat Pensiun, Tunjangan Hari Tua, Dan Jaminan Hari Tua Yang Dibayarkan Sekaligus (PMK
Nomor 16/PMK.03/2010) adalah Objek Pajak Penghasilan Pasal (PPh) 21, akan tetapi
pertimbangan hukum Majelis Hakim dalam Putusan Perkara Nomor 300/Pdt.Sus-
PHI/2020/PN.Jkt.Pst. dan perkara Nomor 372/Pdt.Sus-PHI/2019/Pn.Jkt., tidak memuat tentang
penerapan pemotongan PPh 21 sebagaimana diatur di dalam Pasal 3 ayat (1) PMK Nomor
16/Pmk.03/2010.. Metode yang digunakan dalam penelitian ini adalah yuridis normatif, hasil dari
penelitian ini adalah PMK No. 16/PMK.03/2010 sebagai suatu peraturan perundang-undangan
yang telah berlaku mengikat secara umum belum berlaku efektif dan untuk itu peneliti memberikan
rekomendasi agar dibuatnya kesepahaman antar lembaga dalam hal ini Kementerian Keuangan
Republik Indonesia dengan Mahkamah Agung Republik Indonesia guna menjamin penerapan PMK
No. 16/PMK.03/2010.

Kata Kunci: Peraturan Menteri Keuangan (PMK No. 16/PMK.03/2010), Uang Pesangon, PPH 21,
Putusan Perkara Pengadilan Hubungan Industrial Pada Pengadilan Negeri Jakarta Pusat Nomor:
300/Pdt.Sus-PHI/2020/PN. Jkt. Pst dan Nomor: 372/Pdt.Sus-PHI/2019/PN.Jkt.Pst.).

Abstract
According to the Regulation of the Minister of Finance of the Republic of Indonesia Number
16/PMK.03/2010 concerning Procedures for Withholding Income Tax Article 21 on income in the
form of severance pay, pension benefits, old-age benefits, and old-age benefits that are paid at once
(PMK Number 16/PMK. 03/2010) is the object of Article Income Tax (PPh) 21, but the legal
considerations of the Panel of Judges in the Decision on Case Number 300/Pdt.Sus-
PHI/2020/PN.Jkt.Pst. and case Number 372/Pdt.Sus-PHI/2019/Pn.Jkt., does not contain the
application of withholding PPh 21 as regulated in Article 3 paragraph (1) PMK Number
16/Pmk.03/2010. this research is normative juridical, the result of this research is PMK no.
16/PMK.03/2010 as a legally binding regulation that has generally not been effective and for that
the researcher recommends that an inter-institutional understanding be made in this case the
Ministry of Finance of the Republic of Indonesia and the Supreme Court of the Republic of Indonesia
to ensure the implementation of PMK No. . 16/PMK.03/2010.

Keywords: Minister of Finance Regulation (PMK No. 16/PMK.03/2010), Severance Pay, PPH 21,
Industrial Relations Court Case Decision at the Central Jakarta District Court Number:
300/Pdt.Sus-PHI/2020/PN. Jkt. Pst and Number: 372/Pdt.Sus-PHI/2019/PN.Jkt.Pst.).
KREDIT PEMILIKAN RUMAH DALAM PERSPEKTIF HUKUM PERLINDUNGAN KONSUMEN
Authors: Suparji Suparji , Pratamalistya Akbar Pandu
Published: September 2023

Abstrak

Pengaduan konsumen properti tercatat masih menjadi jenis pengaduan yang
paling banyak diadukan kepada YLKI. Bahkan, pengaduan terkait perlindungan
konsumen properti menempati urutan kedua setelah pengaduan konsumen
perbankan. Tujuan penelitian ini untuk menjelaskan hak kewajiban dan Wewenang konsumen dan produsen perumahan sebagai para pihak yang melakukan perjanjian dalam kredit pemilikan rumah dan menjelaskan peraturan perundang-undangan yang ada dalam melindungi konsumen perumahan melalui transaksi kredit pemilikan rumah. Adapun teori yang digunakan dalam menganalisa permasalahan tersebut penulis menggunakan Teori negara kesejahteraan / teori welfare state, Teori keadilan, Perlindungan konsumen dan Hak-Hak Konsumen Properti di Indonesia. Dari hasil penelitian tersebut dapat disimpulkan bahwa kepuasan konsumen menjadi hal penting dalam memenuhi permintaan atas kebutuhan konsumen sebagai pengguna jasa pengembang perumahan. Konsumen perumahan berhak
mendapatkan produk konstruksi yang sesuai dengan keinginan sebagaimana
tertuang dalam brosur yang ditawarkan/dijanjikan oleh pihak pengembang.

Kata Kunci: Kasus, Tujuan, Teori, Keadilan.
Hubungan Self Management Dengan Tingkat Kepatuhan Pasien Terhadap Keberhasilan Terapi Hipertensi Di Puskesmas Bonorowo Kebumen
Authors: Sridadi Untung , Mika Tri Kumala Swandari  , Tri Fitri Yana Utami
Published: September 2023

Hypertension is a condition when blood pressure systolic over 140mmHg and diastolic blood pressure over 90mmHg . one _ effort for resolve hypertension is with self management or management self with obedience patient to success therapy hypertension . Study this aim for identify characteristics and connection patient and level percentage self management and level obedience patient to success therapy hypertension . Type study this is non - experimental nature correlational with approach cross sectional with use period on month December 2022. Method taking sample on study this that is purposive sampling . Data analysis was performed that is analysis bivariate and test chi square using the Statistical Package for the Social Science (SPSS) program. Study this carried out at the Health Center Bonorowo Kebumen . Population in study this that is all patient hypertension pure nor with participant who did examination at the Health Center as many as 106 respondents on period month December 2022. Based on results study self management sufferer hypertension as much as 49.0% of respondents is at on category enough . A total of 47.2 % of respondents own level obedience medium . There is connection significant Among self management with level compliance ( p-value 0.000) which is correlated (r-0.906) with direction connection positive . Conclusion there is connection significant Among self management with level obedience patient to success therapy hypertension at the health center Bonorowo Kebumen .
Evaluasi Pengelolaan Obat Di Puskesmas Gombong Ii Kabupaten Kebumen Tahun 2022
Authors: Yuliartanti Yesi , Mika Tri Kumala Swandari  , Tatang Tajudin
Published: September 2023

ABSTRAK

Pengelolaan obat yang baik sangat diperlukan untuk peningkatan mutu pelayanan Kesehatan. Pengelolaan obat di Puskesmas Gombong II sudah dilakukan namun belum maksimal dan belum sesuai standar, hal ini sesuai dengan rekomendasi tim surveyor akreditasi tahun 2019 yaitu untuk meningkatkan pengelolaan obat. Penelitian ini bertujuan untuk melakukan evaluasi perencanaan pengadaaan, penerimaan, penyimpanan dan pendistribusian obat di Puskesmas Gombong II Kabupaten Kebumen tahun 2022. Penelitian ini menggunakan metode deskriptif kombinasi kuantitatif dan kualitatif dengan cara membandingkan nilai setiap indikator dengan standar yang ditetapkan oleh Permenkes RI Nomor 74 tahun 2016 dengan penilaian mutu pelayanan kefarmasian di Puskesmas. Pengambilan data retrospektif dari Laporan Pemakaian dan Lembar Permintaan Obat (LPLPO) dan Laporan Penggunaan Obat Rasional (POR) bulan Januari sampai Oktober tahun 2022 serta observasi penyimpanan obat. Hasil penelitian menunjukkan bahwa pengelolaan obat di Puskesmas Gombong II Kabupaten Kebumen Tahun 2022 dengan menggunakan indikator pada tahap perencanaan, pengadaan, penerimaan, penyimpanan dan pendistribusian tahapan pengelolaan obat belum semua indikator sesuai dengan standar. Beberapa indikator pengelolaan obat menunjukkan hasil yang mendekati nilai standar seperti kesesuaian item jumlah penerimaan, kesesuaian jumlah, jenis, dan bentuk sediaan obat, kesesuaian penyimpanan obat, kesesuaian jumlah fisik obat, kesesuaian jumlah item obat perlembar resep dengan nama generik.

Kata kunci : Pengelolaan obat, Evaluasi, Puskesmas, Penyimpanan
LEGAL PROTECTION OF CHILDREN AFTER DIVORCE DIVORCE RELATED TO ACT NUMBER 16 OF 2019 AMENDMENT TO ACT NUMBER 1 OF 1974 CONCERNING MARRIAGE (Decision Study Number 1145/pdt.g/2020/PA.Krw)
Authors: Alfadia Jihan , Abas Muhamad , Arafat Zarisnov
Published: September 2023

Child protection is all activities to ensure and protect children and their rights so that they can live, grow, develop and participate optimally in accordance with human dignity and values, and receive protection from violence and discrimination. Divorce so far often creates problems inherent in children's rights, namely the right to education, health, maintenance costs and so on. In Law Number 1 of 1974 concerning Marriage, it mentions the rights and obligations between parents and children. It is stated in Law Number 1 of 1974 Article 45 Paragraph 1 namely: "Both parents are obliged to look after and educate their children as well as possible, while Paragraph 2 states that: The obligations of the parents referred to in Paragraph I apply until the child marries or can stand-alone. Which obligations continue even though the marriage between the two is broked, the obligation to provide maintenance for their child is not broken and the child still gets his rights as a child. The purpose of this research is to find out the legal protection of children after divorce and to find out the considerations of judges in deciding about legal protection of children after divorce.
Редките доброкачествени хематологични заболявания – отново във фокуса
Authors: Банчев Атанас , Константинов Добрин
Published: September 2023

Класическото разделение на хематологията на „доброкачествена хематология“ или „хематология“ и „злокачествена хематология“ или „онкохематология“ намира все по-осезаемо своята аргументация в съвремието. С изключение на желязонедоимъчната анемия, всички доброкачествени хематологични заболявания – в т.ч. нарушения на хемостазата и тромбозата, хемолитични и наследствени анемии спадат в рубриката на редките болести. В съществената си част се касае за вродени заболявания, изискващи комплексен подход в терапията, съпътстваща живота на отделния индивид и семейството му от люлка до гроб. В този контекст познаването на особеностите на тези нозологични единици е в еднаква степен важно както за специалистите по детска хематология, така и за тези със специалността клинична хематология, транфузионна хематология.

Стремежът към сформиране и работа в мултидисциплинарни екипи за пациенти с редки доброкачествени хематологични заболявания за втора поред година събра различни специалисти в рамките на форума „Haemothal”. В експертната среща взеха участие хематолози, детски хематолози, трансфузиолози, генетици, акушер-гинеколози, ортопеди, ендокринолози, кардиолози и други специалисти, които в рамките на три дни дискутираха в областите на доброкачествената хематология.

Особен фокус в програмата зае грижата за хората с хемофилия и таласемия майор, но беше отделено внимание на пациентките с нарушения в кръвосъсирването, както и на пациентите с тромбоцитните нарушения. Сред лекторите се отличи сериозно участие на колеги от Германия, Норвегия, Република Северна Македония.

С второто издание на форума “Haemothal” организационният комитет прави заявка за създаване на традиционна среща на специалистите, ангажирани в грижата за пациентите с редки доброкачествени хематологични заболявания, с което се надяваме нуждите на тези пациенти да станат все по-разпознати, грижата за тях – все по-съвременна и все по-комплексна.

В следващите страници предлагаме на вниманието Ви избрани доклади от отминалия форум, състоял се в Парк Хотел „Кайлъка“, гр. Плевен през март 2023 г. и пожелаваме ползотворно четене и до нови срещи!
Plasmodium falciparum histoaspartic protease inhibitor: Toxicity investigation and docking study of 2-(2-benzoyl-4-methylphenoxy) quinoline-3-carbaldehyde derivatives
Authors: Aina Oluwafemi S. , Adams Luqman A. , Bello Adebayo J. , Familoni Oluwole B.
Published: September 2023

Aspartic proteases can hydrolyze peptide bonds, making them potential targets for drug development against malaria parasites. In particular, inhibiting the histoaspartic protease (HAP) can disrupt the growth phase of Plasmodium falciparum and its ability to degrade hemoglobin for protein synthesis. Compound 5, specifically designed as 2-(2-benzoyl-4-methylphenoxy)quinoline-3-carbaldehyde, served as the basis for designing 50 hypothetical compounds (A1-A50). These compounds were subjected to in silico screening to assess their toxicity profiles, pharmacokinetics, bioactivity scores, and theoretical binding affinities, as a part of the drug design protocol. Out of the 50 compounds, nine lead candidates showed no toxicity to human cells. In addition, ten standard reference antimalarial drugs were included in this study for comparison. The highest binding energies were observed for compound A5 (−11.2 kcal/mol) and A31 (−11.3 kcal/mol), surpassing the performance of mefloquine, the best reference drug, which ranked ninth with a binding energy of (−9.6 kcal/mol). Compound A31 did not exhibit the evidence of interaction with either Asp215 or His32, whereas compound A5 displayed π-π stacking interactions with His32. Mefloquine also did not show any interaction with Asp215 or His32. Moreover, compound A5 demonstrated greater hydrophobic interactions at the active site with most binding residues, except for Lys7 in the hydrophobic region. This characteristic suggests that compound A5 may have the ability to adopt a smaller surface area, exhibit increased biological activity, and have reduced interactions with water, which could facilitate slower clearance. Based on the assessment of various drug-likeness parameters, compound A5 (2-(2-benzoyl-4-methylphenoxy)-7-methylquinoline-3-carbaldehyde) is a potential lead candidate for the development of a new antimalarial drug.
Miyo pimatisiwin opikinawasowin: Living the good life in child rearing ways
Authors:   , Louis Aimee
Published: September 2023

Opikinawasowin is the Cree word for the lifelong process of growing children. Indigenous child rearing practices adopt a holistic approach while being inclusive of the family unit and the community. The tipi is the conceptual framework for this qualitative Indigenous research study. I use the tipi because each pole represents a specific child rearing teaching corresponding to one of four inter-related life stages: child, adolescent, adult and Elder. All teachings related to the tipi help us understand the spiritual aspect of miyo pimatisiwin opikinawasowin. To be eligible for the Tipi Teachings online study, Indigenous participants are over the age of consent and live on Turtle Island. Thesis findings provide a Turtle Island perspective on Indigenous child rearing ways, teachings, philosophies, and practices related to the tipi. Given that Indigenous children are disproportionately overrepresented in the Child Welfare system, this study is imperative for moving forward in times of reconciliation for Indigenous children, families, communities and Nations across Turtle Island. Thus, this research will positively impact families, including my own, and the next seven generations.
Pengalaman Partisipasi Mahasiswa Keperawatan dalam Praktik Pertolongan Kegawatdaruratan Prarumah Sakit: Studi Fenomenologi dari Kegiatan Olahraga
Authors: Salasa Sehabudin , Sumartini Sri , Putri Suci Tuty , Trisutrisno Imam , Amalia Linda , Rahmi Upik , Andriyani Septian , Pragholapati Andria
Published: September 2023

Penyelenggaraan olahraga berpotensi mengakibatkan kejadian kegawatdaruratan. Kasus trauma fisik merupakan kasus yang sering terjadi, tetapi kejadian henti jantung juga beberapa kali terjadi saat olahraga. Mahasiswa perlu memiliki pengalaman praktik dalam penanganan kegawatdaruratan pada penyelenggaraan olahraga, karena mereka harus siap ditempatkan dimanapun setelah lulus termasuk menjadi tim medis dalam penyelenggaraan olahraga. Penelitian ini bertujuan untuk melakukan eksplorasi pengalaman mahasiswa keperawatan dalam praktik pertolongan kegawatdaruratan dalam penyelenggaraan olahraga. Metode penelitian menggunakan pendekatan kualitatif, dengan jumlah sample 10 orang diambil dengan teknik purposive sampling. Teknik pengambilan data menggunakan teknik wawancara semi-terstruktur dari daftar pertanyaan. Hasil penelitian menunjukan 4 tema diantaranya: Perlu latihan penanganan cedera secara langsung dan spesifik, Merasa tidak percaya diri, Kesenjangan antara yang dipelajari dengan praktik, Kebutuhan kompetensi profesional penanganan cedera. Dapat disimpulkan bahwa penanganan kegawatdaruratan pada olahraga memiliki kekhususan sehingga proses pembelajaran sebelum praktik harus mendapat perhatian yang sama dengan keilmuan lainnya, sehingga kedepan kompetensi penanganan kegawatdaruratan olahraga perlu dimasukan kedalam pokok bahasan dalam kurikulum.
KAJIAN HUKUM TINDAK PIDANA PENCUCIAN UANG DARI ASPEK TINDAK PIDANA EKONOMI
Authors: Sapidin Sapidin , Hutapea Sintong Arion
Published: September 2023

Pelaku kejahatan melakukan pencucian uang hasil kejahatan dalam berbagai bentuk baik dalam bentuk aset fisik berupa harta kekayaan atau aset non fisik dengan memanfaatkan jasa perbankan atau jasa keuangan lainnya baik perseorangan maupun korporasi. Berdasarkan Undang Undang Nomor 8 Tahun 2010 beberapa tindak pidana dapat dikaitkan dengan tindak pidana pencucian uang agar diketahui unsur pencucian uang dalam tindak pidana tersebut. Tindak Pidana Pencucian Uang berdampak terhadap aspek kehidupan masyarakat dan terhadap perekonomian bangsa dan negara. Melalui kajian ini terdapat dua rumusan permasalahan yaitu keberadaan Undang Undang Darurat Nomor 7 Tahun 1955 terkait tindak pidana pencucian uang pada saat ini dan relevansinya sebagai landasan yuridis. Dalam melakukan kajian ini menggunakan metode penelitian yuridis normatif. Tinjauan yuridis yang dilakukan diharapkan dapat memberikan penjelasan yang jelas keterkaitan antara tindak pidana pencucian uang dengan tindak pidana ekonomi dan diharapkan adanya penegakkan hukum yang tegas terhadap pelaku tindak pidana ekonomi dalam menjamin keadilan, kepastian dan  kemanfaatan hukum dalam rangka mencapai tujuan berbangsa dan bernegara.
 
Kata Kunci : Pencucian Uang, Pidana Ekonomi, Perbankan, Penegakan Hukum
Analisis Desain Buku Aktivitas Stiker Tematik untuk Anak Usia Dini
Authors: Susanti Chara
Published: September 2023

Anak usia dini membutuhkan stimulasi yang tepat untuk perkembangan kognitif, sosial, emosional, dan fisik. Proses belajar anak usia dini adalah dengan bermain sambil belajar, sehingga aktivitas anak harus disiapkan yang menyenangkan dan dengan tingkat kesulitan yang sesuai bagi anak. Usborne merupakan penerbit yang berbasis di Inggris dengan spesialisasi buku anak edukatif. Penulis memilih 5 judul buku aktivitas stiker tematik untuk anak usia dini yang diterbitkan Usborne antara tahun 2019 sampai 2021 dengan tema yang beragam. Kelima buku dianalisis dengan metode penelitian kualitatif, metode penelitian visual yang terdiri dari analisis deskriptif, analisis konten, dan analisis konteks. Penelitian ini dilakukan untuk mengetahui pertimbangan apa saja yang terwujud pada rancangan buku aktivitas stiker tematik untuk anak usia dini.
Peran Tipografi Eksperimental Terhadap Visualisasi Lagu Dalam Album Sinestesia
Authors: Cristina Angel , Indrajaya Ferdinand
Published: September 2023

Tipografi dalam lingkup Desain Komunikasi Visual umumnya dipahami sebagai medium komunikasi dalam bentuk kumpulan karakter huruf yang dikomposisikan sedemikian rupa untuk menyampaikan pesan. Pesan yang disampaikan tidak hanya bersifat informatif, dimana tipografi hanya diposisikan sebatas instrumen (sebagai susunan kata) yang berfungsi untuk menjelaskan medium komunikasi visual lainnya seperti ilustrasi atau fotografi. Tipografi juga dapat dipahami lebih dari sekedar susunan teks penjelas gambar (baik secara ilustratif atau fotografis). Keberadaannya dapat dipahami sebagai medium visual yang dramatis dan ekspresif. Sebagaimana dikatakan oleh Rob Carter, anatomi dari bentuk tipografis dapat dieksplorasi lebih jauh dengan tujuan mencapai wujud yang lebih ekspresif. Pendekatan eksploratif ini diterapkan untuk menantang kembali pandangan tradisional dalam tipografi yang instrumental dan fungsional. Pengolahan bentuk, ruang, tekstur, dan warna dalam tipografi dieksplorasi untuk melampaui pemahaman tradisional tersebut. Eksplorasi tipografis semacam ini biasanya dipahami dalam tajuk tipografi eksperimental. Upaya eksperimental ini akan diterapkan pada proyek perancangan ulang album Sinestesia, dimana tipografi berdialog dengan lagu sebagai konten tanpa melupakan peran untuk mengkomunikasikan pesannya. Tahapan proses perancangan visual akan mengacu pada metode perancangan Robin Landa.
Perancangan Aplikasi Mobile Pembelajaran Bahasa dan Aksara Sasak untuk Pelajar Sekolah Dasar
Authors: Hidayat Dicky
Published: September 2023

Perkembangan teknologi di era globalisasi dan modernisasi saat ini menimbulkan banyak dampak bagi masyarakat, salah satunya adalah cara berkomunikasi antar individu atau kelompok. Bahasa dan Aksara Sasak adalah kebudayaan dan identitas suku Sasak sebagai suku asli dari Pulau Lombok, Nusa Tenggara Barat. Saat ini masyarakat Sasak lebih banyak menggunakan Bahasa Sasak Jamaq dibandingkan Sasak Alus. Hanya sebagian masyarakat Sasak yang masih mengenal Asksara Sasak. Ketersediaan media pembelajaran Bahasa dan Aksara Sasak saat ini belum memadai dan lengkap. Media pembelajaran yang tersedia hanya berupa buku-buku cetakan lama dan naskah lontar yang sudah jarang ditemukan. Pembelajaran bahasa dan aksara Sasak sebaiknya dilakukan pada jenjang pendidikan dasar, sehingga dibutuhkan media pembelajaran baru yang lebih interaktif terutama untuk pelajar Sekolah Dasar. Penelitian menggunakan metode penelitian kualitatif deskriptif dengan pengumpulan data berupa observasi, wawancara, dan studi pustaka. Berdasarkan kesimpulan hasil analisis data kemudian dilakukan perancangan menggunakan metode Design Thinking. Hasil perancangan berupa aplikasi mobile pembelajaran Bahasa dan Aksara Sasak untuk pelajar Sekolah Dasar. Hasil perancangan ini diharapkan dapat meningkatkan minat belajar dan penggunaan Bahasa dan Aksara Sasak pada pelajar khususnya Sekolah Dasar di Pulau Lombok, serta memberikan alternatif media pembelajaran yang mempermudah pemahaman serta memberikan pengalaman belajar yang menyenangkan.
Uncertain Random Block Replacement Policy with No Replacement at Failure
Authors: Wu Zheng , Li Xinwang , Feng Min , Shen Hejiao , Zhang Chunxiao
Published: September 2023

The classic block replacement problem assumes the lifetime of component as a random variable, and the downtime cost caused by failed component is a constant. However, when a new type of unit is used in a block replacement system, its lifetime is indeterminate and its distribution cannot be obtained by probability theory due to the lack of historical operational data. And if the component is not replaced immediately when it fails, the downtime cost per unit time is not fixed but always effected by some stochastic factors such as market. Thus, uncertainty and randomness coexist in a block replacement system of new components. In this paper, the lifetime of the component is regarded as an uncertain variable and the downtime cost per unit time is considered as a random variable, and an uncertain random programming model of block replacement with no replacement at failure is developed for a system composed of new type of components, and the formulated model aims to find an optimal replacement time to minimize the expected cost rate in one replacement cycle. An implicit solution of the optimal replacement time is obtained, and the condition ensuring the existence and uniqueness of the optimal replacement time is given. Finally, a numerical example is presented to prove feasibility of the proposed model.
Land use and land cover change influence on soil organic carbon content for a pastoral area: use of geographical information system
Authors: Shadrack M. NJAGI  , Julius Lejju  , John Bosco Nkurunungi
Published: September 2023

Data on land use and cover change and soil organic carbon (SOC) in rangelands are essential. This is because rangelands ecosystems are fragile, and poor land-use practices can significantly threaten their sustainability by depleting SOC and increasing atmospheric carbon dioxide.  This study investigated soil organic carbon variations as influenced by land use/land cover changes in the unprotected area of the Sanga agropastoral ecosystem, southwestern Uganda.  Landsat images provided data for land use and cover for 1987 and 2020. Soil organic carbon contents were investigated in farmland (FL), grassland (GL), woodland (WL), and bare land (BL) as control at 0-15 cm and 15-30 cm depths. Soil samples were analyzed for organic carbon and bulk density using the colorimetric and core ring methods, respectively.  Total soil organic carbon content was significantly high in grassland (31.55 Mg C ha-1), p=0.005, and woodland (27.89 Mg C ha-1), p=0.028 compared to bare land (16.17 Mg C ha-1). Additionally, total soil organic carbon concentration in grassland (2.10%) was higher than SOC concentration in farmland (1.39%) p=0.001 and bare land (1.00%), p<0.001, respectively. Similarly, woodlands soil organic carbon concentration (1.98%) was higher than soil organic concentrations in bare lands, p=0.003 and farmlands, p=0.028. Bulk density was significantly different at lower horizons, with farmland having a higher bulk density than other land use types, p=0.013.  Roots and litter inputs in woodlands and grasslands contributed to higher organic carbon than farmland and eroded/bare lands. Cultivation also increased the soil bulk density. This study concludes that land use and the land cover change affected soil organic carbon sequestration and bulk density. Therefore, farmers need to increase farm management practices to avoid an increase in bulk density. Further study to compare the effects of grazing intensity on SOC and modeling future SOC content in the study area is recommended.
Effect of frying temperature and slice thickness on sensory attributes and acrylamide content in potato crisps of selected Kenyan varieties
Authors: Abong George , Ogolla Jackline , Michael Okoth , Jackson Kabira , Paul Karanja
Published: September 2023

Acrylamide, a chemical found in several carbohydrates rich foods processed at high temperatures, has been classified as a potential human carcinogen; the need to minimize its presence in the human diet cannot be overemphasized. This study was designed to determine how acrylamide formation is influenced by potato varieties, processing temperatures and slice thickness in potato crisp produced from established Kenyan varieties.  Four potato varieties (Kenya Mpya, Sheherekea, Tigoni and Dutch Robjin) were purposively selected due to their suitability for crisp production and were planted at KARLO Tigoni. The potato tubers were harvested at maturity, cured, peeled and sliced into three slice thicknesses (1-0mm, 1.5mm and 2.00mm) and subjected to three frying temperatures of 160°C, 170°C and 180°C until ready. The dry matter of the tubers ranged between 21.5 and 28.4%. The fructose levels ranged from 0.068 - 0.241 %; glucose levels ranged 0.155%- 0.218%; Sucrose levels ranged from 0.61 to 0.87%. In the potato crisps Kenya Mpya variety fried at 160°C of thickness 2.0mm had the highest moisture content of 2.575%.  Most of the crisps from the four varieties processed at different temperatures and thicknesses were light colored with lightness (L*) parameters greater than 50 and towards red as shown by positive values of redness parameter (a*) indicating that there was excess browning of the products during frying. Acrylamide levels significantly (P≤0.05) differed between the varieties and ranged from 3129 to 13480ppb. There was a significant difference in acrylamide levels (p≤0.05) with temperatures of 180°C resulting in higher acrylamide content compared to those of 160°C and 170°C. Similarly, the slice thickness of 2.0mm had high acrylamide levels and the redness parameter (a*). There was a strong correlation between acrylamide formation and glucose (r=0.761) and fructose (r=0.44) formation.
Optimization of acid ensilaging method for the extraction of oil from Lake Victoria nile perch’ lates niloticus viscera
Authors: Aloo Joseph Odhiambo , Wandayi Michael Okoth
Published: September 2023

A study was carried out to optimize the wet acidic rendering for extracting oil from Nile perch viscera. Oil was extracted at 93oC by varying the acid concentration from 0 – 10% and heating time from 5 – 25 minutes. The oil yield, lipolytic, oxidative and color qualities were determined to compare the effect of acid and time using a factorial completely randomized design. Statistical analysis of data was carried out at p  0.05 using GenStat 13th edition software. There was significant difference in yield, with interaction between acid concentration and heating time, the yield being highest at 15 minutes and declining thereafter with increasing acid concentration. There was significant difference in free fatty acids (%FFA), with interaction between acid concentration and heating time, values increasing with acid concentration and heating time. Heating times of 5 and 15 minutes produced the lowest %FFA at 0% acid concentration, being significantly higher after 15 minutes. All the %FFA values were within permitted limits for crude fish oil, however. There was difference in peroxide value (PV) with interaction between acid concentration and heating time, decreasing with increasing concentrations. Heating for 15 and 25 minutes produced lower PV for 0% acid concentration, with no difference between them. But the PVs were within permitted limits for crude fish oil. There were differences in color intensity, with acid concentrations, heating time not producing a significant difference, and the interaction between acid concentration and heating time not significant. There was significant difference in color intensity between 0% and subsequent acid concentrations, increasing with acid concentration. Heating for 15 minutes without acid is therefore the most suitable combination for mass production of crude oil from Nile perch viscera.
Semen quality of progeny-tested breeding bulls maintained at the National Artificial Insemination Centre, Arusha, Tanzania
Authors: Ngoda Patricia , Kashoma Isaac , Msalya George
Published: September 2023

The success or failure of artificial insemination (AI) depends on the quality of semen used. This study was conducted to investigate the effect of breed, age, collection period, and ejaculate number on semen quality collected from 15 breeding bulls available at the centre with different ages (4 Friesian, 4 Ayrshire, 3 Jersey, 2 Simmental and 2 Boran breeds) maintained at National Artificial Insemination Center (NAIC), Arusha, Tanzania. A total of 600 ejaculates were collected for four weeks per month consecutively from January to May 2022, weekly per bull and twice a day; morning (6.00 - 9.00 AM) and evening (3.00 - 6.00 PM) sessions). The ejaculates were first examined visually for volume, color, foreign bodies, and consistency whereas sperm concentration (SPC), progressive motility (PM) and total motility (TM) were assessed using Computer Assisted Semen Analysis System (CASA). Viability/vitality (SPVI) and morphology (SPNR) of sperms were analyzed microscopically after staining with Eosin-Nigrosin. Data were subjected to SAS program and results showed that ejaculate volume, progressive motility, total motility, sperm viability, and morphology were significantly (P<0.05) affected by age and collection period. Simmental, Friesian, and Ayrshire bulls produced more voluminous semen than Jersey and Boran bulls. Jersey bulls had higher (P<0.05) sperm concentrations and live spermatozoa as compared to other bulls. Boran and Jersey's bulls exhibited higher PM and TM than the other bulls. The period of semen collection (morning versus evening) negatively affected semen volume, total motility, and semen viability in which morning harvests performed better than evening collections. Middle aged bulls (3-5 years) produced semen of higher quality compared to other groups (< 3 years and > 5 years old bulls). In conclusion, age, breed, period of semen production and ejaculate number revealed significant effect on bovine semen characteristics.
Semen quality parameters of the Tanzanian Horasi chicken ecotype
Authors: Burilo Amina , Kashoma Isaac
Published: September 2023

Predicting potential fertility and eventual egg hatchability in chickens can be done by evaluating the quality of the semen. This study's objective was to describe the semen characteristics of three different age groups of Horasi chicken ecotype cocks (24-32, 28-36, and 32-40 weeks). From 20 Horasi cocks; 6 cocks (24-32 weeks), 6 cocks (28-36 weeks), and 8 cocks (32-40 weeks) over the course of four weeks (5-29th Dec 2022), 80 semen samples in total were taken. Sperm was harvested from cocks using the abdominal massage technique. The amount of semen, pH, sperm motility, sperm concentration, live spermatozoa percentage, and spermatozoa with normal morphology percentage were all measured. Between the three age groups, the semen volume, pH, sperm motility, sperm concentration, percentage of live spermatozoa, and percentage of spermatozoa with normal morphology ranged from
0.52 ± 0.03mL to 0.68 ± 0.03mL, 7.24 ± 0.01 to 7.31 ± 0.01, 75.16 ± 0.91% to 76.67 ± 1.07%, 4.31 ± 2.27 to 4.56 ± 3.34 × 109 sperm cells/mL, 90.00 ± 0.55% to 91.04 ± 0.85% and 87.78 ± 0.51 to 89.71 ± 0.68% respectively. Only differences in ejaculate volume between the three age groups of Horasi chicken ecotype cocks were significant at p<0.05. The semen quality parameters had extremely low to moderate Pearson correlation coefficients, with values ranging from - 0.22 to 0.38 between sperm concentration and sperm motility, and between the percentage of morphologically normal sperm cells and the percentage of spermatozoa that are alive respectively. The Horasi chicken ecotype's semen parameters are within the normal range, notwithstanding the possibility that individual cocks may differ from one another in some semen characteristics as a result of environmental influences. Using artificial insemination, breeding programs can therefore exploit the Horasi chicken ecotype to increase the productivity of indigenous chickens.
Genesis and New Mineral Chemistry Data of Carlosbarbosaite, a Potential U and Nb Ore Source from Miarolitic-, A-Type Granites and NYF Pegmatites of the La Chinchilla Pluton, Velasco Ranges, La Rioja, Argentina
Authors: Lira Raúl , Parra Francisco J. , Biglia Marco E. , Morello Orquídea , Guereschi Alina B.
Published: September 2023

The La Chinchilla granite is a ∼3.75 km2 epizonal pluton of Lower Carboniferous age located in Sierra de Velasco, Sierras Pampeanas, Argentina. Equigranular micropegmatitic and porphyritic main granite types host abundant millimeter- to <2 m-sized miarolitic pegmatites and pockets of simple major mineralogy (±beryl). Both granite types host micrometer-sized accessory species [i.e., monazite-(Ce), several high field strength element oxide species, ilmenite, cassiterite, fluorapatite] and fluorite. A F-Na-rich fluid phase promoted strong albitization at late-miarolitic stages, along with crystallization of extremely F-rich polylithionite and fluorite, and the formation of replacing pyrochlore group species associated with a second generation of cassiterite. The increase of the Ta# from hydroxycalciopyrochlore to hydroxycalciomicrolite and from micromiarolitic cassiterite (cassiterite 1) to hydrothermal cassiterite (cassiterite 2) supports Nb-Ta fractionation at hydrothermal temperatures. Carlosbarbosaite [(UO2)2Nb2O6(OH)2·2H2O] occurs as a pseudomorphic or short-range transported phase. Low-T, hydrothermal carlosbarbosaite formed after the replacement of columbite-(Fe), U-free Nb-bearing ilmenite, and likely after U-bearing pyrochlore supergroup species and a columbite group mineral, plausibly due to interaction with a hydrothermal, U6+(±Nb±Ta)-enriched fluid, in some cases a SiO2-bearing fluid. This fluid likely represents a lower T, less alkaline, and more oxidizing fluid that evolved from the higher T F-Na-rich fluids active during the late-miarolitic hydrothermal stage. Low-T, hydrothermal carlosbarbosaite has the ideal U-,Nb-rich endmember composition, though it is significantly richer in Ca and poorer in total Nb+Ta but with higher Nb# than that from the type locality. Supergene fluids deposited the transported type, which attained economic concentrations in a fault zone where restricted, likely alkaline oxidizing conditions could have favored Nb mobility.
ENVIRONMENT FOR TEACHING RUSSIAN AS A FOREIGN LANGUAGE IN THE SETTINGS OF DIGITAL EDUCATION TRANSFORMATION
Authors: Богомолов А.Н. , Дунаева Л.А.
Published: September 2023

В статье рассматриваются проблемы функционирования системы обучения РКИ в условиях цифровой трансформации, ставятся вопросы структурирования и контентного наполнения цифровой среды обучения РКИ. На первый план выводится ключевое свойство такой среды – открытость, обусловливающая объединение на основе дидактической целесообразности всех необходимых для обучения средств (учебных и аутентичных, бумажных и мультимедийных, коммуникационных и инструментальных), поддерживаю-щих обучение в очном, смешанном и дистанционном форматах. Определяется типовая структура цифровой среды обучения РКИ, включающая систему взаимосвязанных компонентов, к числу которых отнесены мотивационный, учебный, проектный, программный, методический, управляющий и инструментальный, приводятся примеры ресурсов, составляющих их содержательное наполнение, и результаты проведенного авторами анализа их востребованности с использованием инструмента веб-аналитики «Яндекс Метрика». Намечаются перспективы развития цифровой среды обучения РКИ на основе методической адаптации перспективных цифровых технологий – смарт-устройств, инструментов виртуализации, дополненной реальности, облачных сервисов, мобильного Интернета, искусственного интеллекта, разнообразных интернет-ресурсов и интернет-сервисов для организации образовательной деятельности преподавателя и учащихся.

The article deals with the problems of the functioning of the system of teaching Russian as a foreign language in the context of digital transformation, brings up the issues of structuring and content filling the digital environment for teaching Russian as a foreign language. To the forefront is brought such key property of the environment as openness, which determines the combination, on the basis of didactic expediency, of all the means necessary for learning (educational and authentic, paper and multimedia, communication and instrumental), supporting learning in full-time, blended and distance formats. The typical structure of the digital learning environment of Russian as a foreign language is determined, including a system of interrelated components, which include motivational, educational, project, program, methodological, managerial and instrumental, examples of resources that make up their content, and the results of the analysis of their demand using the tool web analytics "Yandex Metrika". Prospects are outlined for the development of a digital learning environment for Russian as a foreign language based on the methodological adaptation of perspective digital technologies – smart devices, virtualization tools, augmented reality, cloud services, mobile Internet, artificial intelligence, various Internet resources and Internet services for organizing the educational activities of teachers and students.
Absolute grammatical tense in the reproductive register
Authors: Роговнева Ю.В.
Published: September 2023

В статье анализируется, как абсолютное грамматическое время может влиять на регистровую принадлежность предложения, а в некоторых случаях и определять ее. Доказывается, что настоящее время – это база для репродуктивного регистра, прошедшее время также может функционировать в репродуктивной конструкции, однако при некоторых условиях оно представляет регистр информативный. Будущее время нерегулярно появляется в нефикциональных текстах и выводит предложения в информативный регистр.

The article analyzes how the absolute grammatical tense can affect the communicative register of a sentence. It is proved that the present tense is the basis for the reproductive register, the past tense can also function in the reproductive structure, but under certain conditions it represents an informative register. The future tense appears irregularly in non-functional texts and outputs sentences in an informative register.