bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH PEMBERIAN THE EUPHORBIA MILII DAN PROPOLIS TERHADAP GAMBARAN HISTOLOGIS GINJAL TIKUS WISTAR JANTAN
Authors: Wicaksana I Dewa Agung Gede Oka Dwi , Linawati Ni Made , Arijana IGK Nyoman , Ratnayanti I Gusti Ayu Dewi
Published: January 2024

ABSTRAK

 

Pendahuluan: Terdapat beraneka ragam macam obat-obatan herbal yag tersebar di Indonesia, baik yang berbahan asal dari hewan atau tumbuhan. Obat tradisional yang terdapat di Indonesia salah satunya adalah penggunaan Euphorbia milii dan propolis, yang memiliki manfaat sebagai imunomodulator dan bersifat antioksidan. Penggunaan obat tradisional dengan dosis dan interval waktu yang tidak menentu tentunya dapat menimbulkan adanya beberapa efek atau dampak lain. Tujuan dari pelaksanaan studi ini yaitu untuk dapat menentukan pengaruh pemberian teh kombinasi Euphorbia milii dan propolis terhadap gambaran histologi ginjal tikus wistar jantan. Metode: Pada studi ini menggunakan jenis rancangan berupa randomized post test only controlled group. Sebanyak 4 kelompok tikus diambil dari 24 ekor tikus wistar jantan dengan rentang usia antara 2-3 bulan serta dengan berat badan ± 200 gram. Kelompok kontrol (P) diberikan aquabidest, sedangkan kelompok perlakuan (P1-P3) diberikan teh kombinasi Euphorbia milii dan propolis, kemudian diterminasi yang dilanjutkan dengan pemeriksaan gambaran histologis ginjal melalui pengukuran diameter glomerulus. Teknik analisis data dalam penelitian ini adalah One Way Anova dan Post Hoc dengan tes LSD . Hasil: Hasil analisis data dari rerata diameter glomerulus, tidak dijumpai adanya perbedaan antara kelompok kontrol (K) dengan kelompok perlakuan (P1-P3) terhadap rerata diameter glomerulus. Simpulan: Berdasar atas hasil dari studi penelitian ini, dapat ditarik kesimpulan bahwa pemberian teh Euphorbia mili dan propolis tidak menimbulkan kerusakan yang bermakna terhadap ginjal tikus wistar jantan.

Kata kunci :  Euphorbia milii, propolis, diameter glomerulus
Prevalensi dan Karakteristik Sindroma Mata Kering pada Mahasiswa Semester Enam PSSKPD FK Unud
Authors: Widnyana Nyoman Satria
Published: January 2024

Dry Eye Syndrome (DES) is a multifactorial disease that disturb eye tears homeostasis and ocular surface. This research purposes are to identify the prevalence and the characteristics of DES in medical student, Program Studi Sarjana Kedokteran dan Profesi Dokter (PSSKPD), Fakultas Kedokteran, Universitas Udayana (FK Unud). This research is a descriptive cross-sectional. Ocular Surface Disease Index (OSDI) questionnaire is used to identify the prevalence and risk factors questionnaire such as gender, BMI, history of allergy, frequent use of over the counter (OTC) eye drops, frequent use of contact lens, and sleep quality, is used to identify the characteristics. This research conducted from March until September 2020. This research use total sampling method managed to collect 199 sample. The results of the study show the prevalence of DES in Preclinical Student of PSSKPD FK Unud is 106 students (52.7%) with 21% on mild severity, 15% on moderate severity, and 18% on severe severity. The characteristics of DES based on gender is 54% for male and 52% for female; on BMI are 40% for <18 kg/m2, 55% for 18-25 kg/m2, 47% for >25 kg/m2; on history of allergy is 47%; on history of OTC drug is 70%; on history of contact lens utilization is 64%; based abnormal quality of sleep is 64%.
Prevalence and Related Factor of Asthma Towards Children Aged 13rd-14th in Rural Area
Authors: Wanami Putri Ni Made Wini Jayesthiwi , Mayangsari Ayu Setyorini Mestika , Sidiartha I Gusti Lanang , Adnyana I Gusti Agung Ngurah Sugitha
Published: January 2024

There are 300 million people in all aged have an asthma, or it reach 1-16% prevalent of asthma in children worldwide. The study of prevalence and risk related factors of asthma in rural daerah is still very limited nowadays. The design of this study is cross-sectional quantitative study, with epidemiology analytic design. This study was conducted in Junior High School 1 in Sukawati, Sukawati Village, Gianyar, Bali. There are 557 samples of children aged 13rd-14th. The samples were collected based on constitutional sampling method. This study used ISAAC (International Study of Asthma and Allergies in Childhood) electronic questionnaires. The aims of this study was to determine the relation between prevalence of asthma and its related factors dermatitis atopic, allergies rhinitis, states of nutrition, atopic diseases in family, passive smokers, and fast food consumption in rural daerah in Bali. Prevalence of asthma in Bali in this study is 7.5%. Based on the analysis, allergic rhinitis (RP= 2.09 IK95%= 1.1-3.72 p= 0.01), atopic dermatitis (RP=4.33 IK95%=2.34-8.02 p=0.0001), and atopic diseases in family (RP= 2.56 IK95%=1.42-4.63 p=0.001), had a significant difference result with the prevalence of asthma. Besides, obesity (RP=0.98 IK95%=0.48-2.0 p=0.96), passive smokers (RP=1.52 IK95%=0.84-2.74 p=0.16), and fast food consumption (RP=1.24 IK95%=0.65-2.35 p=0.51), did not have any significant different result with the prevalence of asthma. Internal risk factors have a significant result towards the prevalence of asthma. Meanwhile, external risk factors need more exploration and research to know its effect on exacerbation and incident of asthma.

Keyword: Asthma, ISAAC, Prevalence, Related Factors
Tingkat Pengetahuan Ibu Mengenai MP-ASI di Puskesmas Rendang Karangasem
Authors: Rathasari Ni Made Dea Adilla
Published: January 2024

Kualitas seorang anak dipengaruhi oleh nutrisi yang diberikan dalam proses tumbuh kembang. Pada awalnya, nutrisi yang dibutuhkan yaitu Air Susu Ibu (ASI) dan dilanjutkan dengan asupan makanan tambahan yaitu Makanan Pendamping Air Susu Ibu (MP-ASI) mulai usia 6-24 bulan. Keberhasilan dalam mewujudkan MP-ASI didukung oleh pengetahuan ibu. Salah satu faktor yang memengaruhi pengetahuan adalah tingkat pendidikan. Berdasarkan data profil Kesehatan Provinsi tahun 2019, pada bagian cakupan pemerliharaan kesehatan anak mendapatkan hasil bahwa Kabupaten Karangasem merupakan kabupaten terendah dari 9 kabupaten di Bali. Pada studi pendahuluan yang dilakukan di Puskesmas Rendang Karangasem, mendapatkan hasil bahwa ibu belum sepenuhnya mengerti mengenai MP-ASI. Oleh karena itu, diperlukan penelitian untuk mengetahui tingkat pengetahuan ibu mengenai MP-ASI. Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan ibu mengenai MP-ASI di Puskesmas Rendang Karangasem. Desain penelitian ini adalah penelitian potong lintang deskriptif dengan teknik consecutive sampling. Penelitian ini dilakukan di Puskesmas Rendang Karangasem yang dilakukan pada bulan Juni hingga Agustus 2020. Subyek penelitian ini adalah ibu yang memiliki bayi berusia 6-24 bulan yang melakukan pengobatan di Puskesmas Rendang Karangasem dan didapatkan 72 responden yang memenuhi kriteria inklusi. Data penelitian ini adalah data primer yang diperoleh dari kuesioner kemudian diolah menggunakan SPSS versi 20. Dalam analisis univariat dan bivariat didapatkan hasil bahwa sebagian besar tingkat pengetahuan ibu dalam kategori cukup dengan tingkat pendidikan terbanyak yaitu SMP dan pekerjaan sebagai pedagang.

Kata kunci :  Ibu, MP-ASI, Pengetahuan
STATUS RESISTENSI Aedes aegypti TERHADAP MALATHION 0,8% DI KELURAHAN LABUH BARU TIMUR KECAMATAN PAYUNG SEKAKI KOTA PEKANBARU
Authors: Susanty Elva , Lesmana Suri Dwi , Taufik Rigandi
Published: January 2024

Malathion merupakan salah satu jenis insektisida yang telah lama digunakan dalam pemberantasan vektor Demam Berdarah Dengue (DBD) yaitu Aedes aegypti (Ae.aegypti) Pemakaian insektisida dalam jangka waktu lama dapat menimbulkan efek samping seperti resistensi. Tujuan penelitian adalah untuk mengetahui status resistensi A.aegypti terhadap malathion 0,8% di Kelurahan Labuh Baru Timur.  Penelitian ini merupakan penelitian observasional deskriptif dengan desain cross-sectional. Larva Ae.aegypti diambil dari 4 RW di Kelurahan Labuh Baru Timur, kemudian dibawa ke laboratorium Parasitologi Fakultas Kedokteran Universitas Riau untuk dipelihara menjadi nyamuk dewasa. Metode uji resistensi yang digunakan adalah metode susceptibility test WHO dengan impregnated paper malathion 0,8%. Nyamuk dipindahkan tabung paparan yang sudah diberi malathion 0,8% dan tabung kontrol masing-masing sebanyak 25 ekor kemudian diamati selama 1 jam untuk melihat nyamuk knockdown. Selanjutnya nyamuk Ae.aegypti dipindahkan ke holding tube, diletakkan pada ruangan selama 24 jam kemudian dihitung mortalitas nyamuk. Hasil penelitian ini menunjukkan mortalitas  nyamuk Ae.aegypti 24 jam setelah paparn malathion 0,8% adalah 10%. Pemakaian insektisida dalam jangka waktu lama tidak efektif untuk mengeliminasi vektor demam berdarah karena dapat menimbulkan resistensi. Status resistensi nyamuk A.aegypti di Kelurahan Labuh Baru Timur terhadap malathion 0,8% adalah resisten. Perlu adanya rotasi pemakaian malathion dalam pengendalian Ae.aegyptisebagai vektor DBD.

 

Kata kunci :  malathion, resistensi, susceptibility test WHO
HUBUNGAN POLA KONSUMSI ANAK DI KANTIN SEKOLAH DENGAN OBESITAS DI SD NEGERI 17 DANGIN PURIi
Authors: Jumantini Ni Komang Pasek Nurhyang , Wati Dyah Kanya , Subanada Ida Bagus , Suparyatha Ida Bagus Gede
Published: January 2024

ABSTRAK

Obesitas kini telah menjadi tantangan kesehatan. Kasus obesitas pada anak menjadi salah satu permasalahan yang perlu diperhatikan. Pada tahun 2016, obesitas terjadi pada lebih dari 650 juta orang dengan melampaui angka 340 juta anak dan remaja usia 5-19 tahun mengalami obesitas. Obesitas terjadi akibat ketidakseimbangan antara intake energi dan energi yang digunakan tubuh. Obesitas merupakan penyakit multifakatorial. Pada anak usia sekolah dasar, pola konsumsi di kantin sekolah berkontribusi besar terhadap kasus obesitas. Anak usia sekolah dasar cenderung memiliki kebiasaan jajan di kantin sekolah. Makanan tinggi karbohidrat dan lemak mendominasi jajanan di kantin sekolah, seperti gorengan, makanan ringan (snack), sosis, aneka kue, cokelat, dan makanan cepat saji lainnya serta berbagai jenis minuman. Penelitian ini bertujuan untuk mengetahui apakah terdapat hubungan pola konsumsi anak di kantin sekolah dengan kejadian obesitas anak. Penelitian ini merupakan penelitian observasional dengan metode pengambilan data cross-sectional dan pengumpulan data dilakukan dengan wawancara dan pengukuran antropometri. Penelitian ini dilakukan di SD Negeri 17 Dangin Puri, dengan besar sampel sebanyak 66 responden. Berdasarkan hasil penelitian, ditemukan adanya hubungan bermakna antara pola konsumsi tidak seimbang di kantin sekolah anak dengan status gizi obesitas (OR=5,400; IK 95% 1,185-24,597; p=0,029), dan adanya hubungan bermakna antara aktifitas fisis dengan status gizi anak (OR=0,165; IK 95% 0,036-0,749; p=0,020). Kesimpulan dari penelitian ini bahwa terdapat hubungan pola konsumsi anak di kantin sekolah dengan kejadian obesitas.

Kata kunci :  obesitas, anak sekolah dasar, pola konsumsi  di kantin sekolah
PENGARUH TESTOSTERONE REPLACEMENT THERAPY TERHADAP PROFIL LIPID DAN LEMAK PADA TUBUH
Authors: Irawan Angeline Aprilia , Kurniawan Yukhi , Satriyasa Bagus Komang , Widianti I Gusti Ayu
Published: January 2024

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After turning 40 years old, testosterone hormone in men will decrease, but some data regarding the effect of Testosterone Replacement Therapy (TRT) on cardiovascular safety is still controversial. The aim of this systematic review is to investigate the effect of TRT on lipid profile and body fat in men with Late-Onset Hypogonadism (LOH) which affects the incidence of cardiovascular disease.

The literature search was performed on the database, such as PubMed and Wiley Online Library and also additional manual searches were performed on the reference list of related studies. The identified articles were selected according to the eligibility criteria. A total of four articles were used in this systematic review and the quality of the study was assessed using the Jadad score.

From the four studies that is used, four study discussed the effect of TRT on lipid profiles and two studies discussed the effect of TRT on body fat. On the administration of testosterone gel 50mg/day, all lipid profiles improved after nine months of intervention. However, with IM testosterone after one year, the improvement was only partial. All studies discussing the effect of TRT on body fat showed uniform results, namely a decrease in fat percentage.

The results obtained by the studies included in this systematic review suggest that TRT can improve lipid profiles and also decrease body fat in men with LOH.
KARAKTERISTIK MENOPAUSE PADA PERAWAT DI RSUP SANGLAH DENPASAR TAHUN 2021
Authors: Kirana Ni Wayan Kartika Candra , Surya I Gede Ngurah Harry Wijaya , Manuaba Ida Bagus Gede Fajar , Mulyana Ryan Saktika
Published: January 2024

The age of menopause varies in each woman, due to differences in the characteristics of certain factors that are thought to have an effect. This study aims to determine the age of menopause and the characteristics of education level, marital status, parity, age of menarche, age of first birth, history of hormonal contraceptive use, and Body Mass Index in postmenopausal nurses at Sanglah General Hospital Denpasar in 2021. This study is an observational descriptive study with a cross-sectional approach. The sample consisted of 60 respondents who were collected by total sampling method. Data were collected through interviews using a questionnaire. The results showed that 88,3% experienced menopause at the age of >45 years with the most distribution at the age of 50 years (30%). The characteristics of respondents were as follows, namely 100% in married, 88,3% completed D3/S1/S2/S3, 73,3% had given birth to 1-2 children, 88,3% gave birth to their first child at the age of 20-29 years, 58,3% menarche at age > 14 years, 61,7% never used hormonal contraception, 51,7% are obese I. The results of this study are expected to be used as a basis for further research to determine the association between the characteristics of a woman and menopausal age.

Keywords : menopause, menopausal age, characteristics.
GAMBARAN KELUHAN MENOPAUSE PADA PERAWAT DI RSUP SANGLAH DENPASAR PERIODE 2021
Authors: Wahyudi Jaya Nyoman Dedy Ari
Published: January 2024

Menopause merupakan peristiwa normal yang dialami oleh setiap wanita yang menandakan masa reproduksi seorang wanita telah usai. Peristiwa tersebut dikarenakan indung telur mengalami proses penuaan, sehingga produksi hormon estrogen menurun dan menyebabkan terjadinya kenaikan kadar hormon FSH dan LH. Gejala-gejala menopause bisa sangat mengganggu, terutama karena terjadi pada saat wanita memiliki peran penting dalam keluarga dan di tempat kerja. Perubahan hormon yang dimulai selama menopause mempengaruhi banyak sistem biologis. Berdasarkan hal tersebut, sangat penting bagi masyarakat khususnya wanita untuk mengetahui gejala-gejala yang timbul ketika mengalami menopause agar dapat mempersiapkan diri dalam menghadapi menopause. Penelitian ini merupakan penelitian desktriptif dengan desain studi cross-sectional, yang dilaksanakan di RSUP Sanglah Denpasar dengan sampel yakni perawat wanita yang telah menopause dan memenuhi kriteria inklusi. Dari penelitian yang dilakukan, didapatkan hasil bahwa rasio kejadian keluhan-keluhan menopause pada perawat wanita yang telah menopause di RSUP Sanglah Denpasar ialah sebagai berikut: 16,7% keluhan vasomotor, 58,3% keluhan kognitif, 40% keluhan urogenital, 51,7% keluhan gangguan tidur, 13,4% keluhan seksual, 50% keluhan muskuloskeletal, dan 46,7% keluhan emosional.
Karakteristik Pasien Kanker Serviks Stadium IIB Pasca Kemoterapi Neoadjuvant di RSUP Sanglah Denpasar Tahun 2020-2021
Authors: Satriawan Nyoman Gede Dikawijaya , Winata I Gde Sastra , Pangkahila Evert Solomon , Manuaba Ida Bagus Gede Fajar
Published: January 2024

Kanker serviks adalah keganasan pada leher rahim akibat human papilloma virus. Terapi pada kasus kanker serviks stadium IIB adalah kemoterapi neoadjuvant. Tujuan dari penelitian ini untuk mengetahui karakteristik berdasarkan usia, tipe histopatologi, riwayat keluarga, paritas, riwayat kontrasepsi, respon kemoterapi, dan status operabilitas pada kasus kanker serviks stadium IIB pasca kemoterapi neoadjuvant di RSUP Sanglah Denpasar. Penelitian ini merupakan penelitian deskriptif retrospektif yang bersumber dari rekam medis pasien dengan teknik total sampling. Populasi dan sampel penelitian ini adalah pasien kanker serviks stadium IIB pasca kemoterapi neoadjuvant di RSUP Sanglah Denpasar periode 2020-2021 sesuai kriteria inklusi. Hasil penelitian menunjukkan terdapat 40 pasien kanker serviks stadium IIB dengan jumlah kasus tertinggi usia 40-49 tahun (45%). Tipe histopatologi tersering squamous cell carcinoma (85%). Pasien tanpa riwayat keluarga menderita kanker serviks sejumlah 92,5%. Pasien dengan jumlah paritas >2 sebanyak 52,5%. Pasien dengan riwayat penggunaan kontrasepsi sebanyak 65%. Respon kemoterapi baik lebih banyak ditemukan sebesar 70%. Status pasien operabel sebesar 57,5%.

Kata kunci :  karakteristik, kanker serviks stadium IIB, kemoterapi neoadjuvant.
MEKANISME KOPING MALADAPTIF BERKAITAN DENGAN PROPORSI KECEMASAN: STUDI POTONG LINTANG PADA MAHASISWA PENDIDIKAN DOKTER
Authors: Sandra Sandra , Lesmana Cokorda Bagus Jaya , Aryani Luh Nyoman Alit , Wardani Ida Aju Kusuma
Published: January 2024

Pandemi Corona Virus Disease 2019 (COVID-19) memberikan banyak dampak untuk kesehatan, termasuk kesehatan mental. Kecemasan merupakan salah satu masalah yang timbul dalam situasi pandemi dan disebabkan oleh berbagai faktor. Mahasiswa kedokteran merupakan salah satu populasi yang rentan mengalami gejala kecemasan dibandingkan populasi lainnya. Dengan demikian, strategi koping yang tepat dapat membantu penanganan kecemasan. Penelitian ini bertujuan untuk melihat perbedaan proporsi tingkat kecemasan pada mahasiswa Fakultas Kedokteran Universitas Udayana berdasarkan mekanisme koping yang banyak diterapkan. Studi ini menggunakan desain analitik potong lintang pada 311 mahasiswa pendidikan dokter Universitas Udayana angkatan 2018-2020 yang aktif mengikuti perkuliahan secara daring selama pandemi. Mekanisme koping dan kecemasan diukur dengan kuesioner Brief COPE dan Generalized Anxiety Disorder-7 (GAD-7) melalui Google Form dan dikerjakan secara mandiri oleh responden. Analisis data menemukan perbedaan proporsi yang signifikan antara mekanisme koping dan tingkat kecemasan (p = 0,002; <0,05). Rasio prevalensi menunjukkan bahwa mekanisme koping maladaptif 2,104 dan 2,122 kali lebih tinggi menyebabkan kecemasan sedang-berat dibandingkan koping sedang dan adaptif. Mekanisme koping adaptif dan maladaptif yang banyak digunakan oleh responden adalah koping aktif dan penghindaran secara berurutan. Perbedaan tahun angkatan (p = 0,000; <0,05) dan usia (p = 0,000; <0,05) memiliki perbedaan proporsi yang signifikan pada tingkat kecemasan, namun tidak dengan jenis kelamin (p = 0,103; >0,05). Mekanisme koping adaptif dan maladaptif ditemukan memiliki perbedaan proporsi tingkat kecemasan yang berbeda secara signifikan, yang mana prevalensi kecemasan berat ditemukan meningkat pada koping maladaptif. Penerapan mekanisme koping yang adaptif akan membantu mahasiswa dalam menghadapi penyebab kecemasannya.
Kata Kunci: Kecemasan. Mahasiswa Kedokteran, Mekanisme Koping
PENGARUH PEMBERIAN EKSTRAK UBI JALAR UNGU DAN EKSTRAK BUAH BIT TERHADAP KADAR KOLESTEROL PADA TIKUS WISTAR YANG DIBERI DIET TINGGI LEMAK
Authors: Tohjiwa G. Raditya , Wahyuniari Ida Ayu Ika , Linawati Ni Made , Arijana I G Kamasan Nyoman
Published: January 2024

Cardiovascular disease is a disease that often occurs in Indonesia. Cholesterol and free radicals can stimulate an increase in oxidative stress on the walls of the coronary arteries which can trigger coronary heart disease. Ipomea Batatas and Beta Vulgaris L contain flavonoids and betalains which is useful to lower cholesterol levels in the body to prevent cardiovascular disease. This study aimed to determine the effect of the combination of purple sweet potato and beetroot extract on cholesterol levels in rats fed a high-fat diet. The study design was an experimental study using the Post Test Only Control Group Design method with a sample of 24 male wistar rats fed a high-fat diet and divided into 4 groups. Aquadest was given to the control group (K-) while Ipomea Batatas extract (P1), Beta Vulgaris L extract (P2) and a combination of Ipomea Batatas and Beta Vulgaris L extract (P3) were given to the treatment group. Cholesterol levels will be tested using photometrics with Diasys Cholesterol reagent using blood serum. Data is analyzed with One Way ANOVA. This research showed that there were significant differences in cholesterol levels between the control group and the treatment group given purple sweet potato extract and combination extract with a P value <0.05. The cholesterol level of Group K- 116.8 mg/dL, P1 88.8 mg/dL, P2 99.0 mg/dL, and P3 92.5 mg/dL In conclusion, purple sweet potato extract and the combination extract could reduce cholesterol levels in male wistar rats fed a high-fat diet.

Keywords: Ipomoea batatas, Beta vulgaris L, Cholesterol Levels
PREVALENCE OF Salmonella sp. AND Shigella sp. BACTERIAL CONTAMINATION ON CHICKEN MEAT SOLD BY TRADITIONAL MARKET TRADERS IN DENPASAR CITY
Authors: Surya Putra I Gusti Agung Utama , Darwinata Agus Eka , Putra Pinatih Komang Januartha , Fatmawati Ni Nengah Dwi
Published: January 2024

Salmonella sp. and Shigella sp. are bacterias that have become the most frequent cause of foodborne illness in developing countries. One of its contamination is chicken meat which is a daily staple food. The contamination occurs if the processing, storage, and distribution of chicken meat are improper. The aim of this study was to find the prevalence of contamination by Salmonella sp. and Shigella sp. on chicken meat sold by traditional market traders in Denpasar City. The type of research is cross-sectional research with descriptive observational. This study used the cluster sampling method. The total of samples is 24 samples and were taken from six traditional markets in each district of Denpasar City. Identification of Salmonella sp. and Shigella sp.Bacteria was done at the Integrated Biomedical Laboratory of Medical Faculty of Udayana with the culture method on Salmonella-Shigella agar media and Simmons Citrate culture. The total percentage contamination of Salmonella sp. was 58.33% (14/24), while Shigella sp. 20.83% (5/24). This bacterial contamination is caused by the lack of attention to hygiene in every chicken meat processing, storage, and distribution. The researcher suggests that further similar research be carried out using advanced identification methods to distinguish bacterial colonies in more detail and conduct a quantitative assessment of environmental contamination where chicken traders live.
The Characteristics And Rationality Of Treatment Of Diabetic Neuropaty In Elderly With T2DM At Private Hospital X In Denpasar On March-May 2021
Authors: Putrawan Ida Bagus Indra Shadnyana , Indrayani Agung Wiwiek , Mahendra Agung Nova , Dewi Ni Wayan Sucindra
Published: January 2024

Diabetic neuropathy (ND) is the very common complication caused by type 2 diabetes mellitus (DM), DM is an epidemic in the elderly group. Elderly can be defined as someone that has come to the age of > 60 years and is said to have entered the final stage of the life phase. The aging process experienced by the elderly is cued by the phase of reduction in many functions of the body's organs called degenerative. This special conditions experienced by the elderly are accompanied by several diseases or complications so that they get relatively many types of drugs called polypharmacy, this causes a clinician to consider giving treatment to the elderly in order to minimize the side effects or toxic effects of a drug. This research aims to specify the characteristics and rationality of treatment for diabetic neuropathy in the elderly. This research is a quantitative descriptive study with a cross sectional design. In this study using purposive sampling technique with a sample size of 110 samples taken at the neurology polyclinic of the private hospital x in Denpasar. All samples were processed using SPSS 22.0 and Microsoft Excel and obtained 7 types of drugs and the most drug use are 55 (50%) of gabapentin with vitamin B complex as adjuvant therapy as many as 102 (92.7%) and 106 (96.3%) ) sample received more than 1 drug. In this study, the treatment given is a rational drug choice to treat ND in the elderly.
KORELASI ASPECT SCORE DENGAN NIHSS, GCS, DAN LAMA DIRAWAT PADA PASIEN STROKE NON HEMORAGIK AKUT DI RSUP SANGLAH
Authors: Juniada Putu Herry , Asih Made Widhi , Margiani Ni Nyoman , Eka Putra I Wayan Gede Artawan , Martadiani Elysanti Dwi , Mahendra Wijaya I Gusti Agung Gede
Published: January 2024

Stroke adalah kondisi medis mengancam nyawa, akibat terputusnya pasokan darah ke bagian otak tertentu, bisa diakibatkan oleh pembuluh darah otak yang pecah (stroke hemoragik), maupun tersumbat (stroke non hemoragik). Stroke Non Hemoragik (SNH) membutuhkan penanganan segera dengan terapi trombolisis (IV-rtPA) dalam 3-4,5 jam pasca awitan SNH untuk menurunkan angka morbiditas dan mortalitas. Salah satu metode penilaian kelayakan pasien SNH (melalui pencitraan otak) untuk menerima terapi trombolisis adalah dengan ASPECT Score. Namun IV-rtPA dan ASPECT Score masih sangat jarang diterapkan karena berbagai faktor, sehingga untuk saat ini kami memiliki gagasan untuk meneliti bagaimana korelasi ASPECT Score dengan NIHSS, GCS, dan lama dirawat pada pasien SNH akut. Harapannya dapat ikut mempromosikan ASPECT Score, agar semua stakeholder lebih akrab dengan ASPECT Score jika sudah siap dengan terapi IV-rtPA nantinya. Penelitian ini adalah penelitian observasional analitik dengan pendekatan cross-sectional prospektif. Pasien SNH yang masuk IGD RSUP Sanglah pada bulan Oktober 2021 – Januari 2022 yang memenuhi kriteria inklusi dan eksklusi dipilih secara consecutive sampling sebanyak 66 sampel. Hasil pemeriksaan CT scan kepala tanpa kontras diambil dari PACS dan dilakukan penilaian ASPECT Score oleh 2 orang radiolog secara terpisah. Terdapat Interobserver Agreement penilaian ASPECT Score yang tinggi dan bermakna antara observer 1 dan 2 (r = 0,905; p = 0,00; 95% Limits of Agreement = -1,161 – 0,889). Namun ternyata tidak terdapat korelasi yang bermakna antara ASPECT Score dengan NIHSS, GCS, dan lama dirawat, yaitu dengan nilai r dan p masing-masing adalah r = -0,144, p = 0,250; r = 0,069, p = 0,584; dan r = -0,111, p = 0,375. Perlu dilakukan perbaikan design penelitian, contohnya dengan pendekatan longitudinal untuk mengakomodasi progresivitas infark, dan dengan membandingkan antara penilaian ASPECT Score melalui pemeriksaan CT scan dengan MRI (DWI) yang dikenal lebih sensitif dalam mengidentifikasi perubahan iskemik tahap awal.

Kata kunci :  ASPECT Score, NIHSS, GCS
Characteristics of Hematology Examination Results and Speed of Recovery of DHF Patients at Bali Mandara Hospital in 2019-2020
Authors: Nugraha Ketut Yoga Wira , Subawa Anak Agung Ngurah , Herawati Sianny , Mulyantari Ni Kadek
Published: January 2024

ABSTRACT

Dengue Hemorrhagic Fever (DHF) as one of the most common infectious diseases in the world is still a major concern even though the incidence and mortality rates have decreased. The study objective is to determine hematological examination results and the speed of recovery of DHF patients reviewed according to age, gender, BMI, degree of DHF, and duration of fever before being treated. This was cross-sectional study using secondary data from medical records of 193 DHF patients treated from year 2019 to 2020. In 193 patients, before being admitted to the hospital, the patient had an average fever for 4.12±1.16 days with an average 4.69±1.2 days of hospitalization. Hematological test on hospital admission showed the average platelet value was 83.06±28.74 x103 cells/µL with 187 (96.9%) patients had platelet values below the normal value. Average leukocyte count was 4.13±2.01 x 103 cells/µL with 126 (65.3%) patients having a leukocyte value below the normal value. Average hematocrit value was 40.31±4.96% with 113 (58.6%) patients had normal hematocrit values. The duration of hospitalization for DHF patients had a significant difference when viewed according to age (p=0.000), BMI (p=0.000), and duration of fever before being treated (p=0.000). The mean platelet values were significantly different when compared according to the duration of fever before being treated (p=0.018). The mean leukocyte values were significantly different when compared according to age (p=0.007) and gender (p=0.008). The mean hematocrit value was significantly different when compared according to age (p=0.000) and gender (p=0.008).

Keywords: Dengue hemorrhagic fever, hematological examination, duration of hospitalization
Gambaran Klinikopatologik Lupus Nefritis di RSUP Sanglah Denpasar tahun 2016-2020
Authors: Nariswari Ida Ayu Ista , Winarti Ni Wayan , Sriwidyani Ni Putu , Dewi I Gusti Ayu Sri Mahendra
Published: January 2024

ABSTRACT

 

Systemic lupus erythematosus (SLE) is one of the most common autoimmune diseases in the community. One of common clinical manifestations of SLE is Lupus Nephritis (LN). The World Health Organization (WHO) notes that there are five million people with lupus in the world and there are 100,000 more new sufferers every year. In Indonesia in 2016 it was reported that 2,166 patients were hospitalized with a diagnosis of SLE and 550 of them died. This study aims to determine the characteristics of LN patients at Sanglah Hospital Denpasar in 2016-2020 based on age, gender, histopathological class (categorized according to ISN/RPS), and proteinuria level and to determine the relationship between proteinuria level and histopathological class and the relationship between age and histopathological class. This research was conducted at the Anatomical Pathology (PA) laboratory of Sanglah Hospital Denpasar in 2021 with a cross-sectional method, using secondary data that available at the PA laboratory of Sanglah Hospital Denpasar, then processed using SPSS ver. 26. The results showed that the total number of LN patients at Sanglah Hospital Denpasar in 2016-2020 was 28 cases. Most cases were found at age range of 26-35 years (11 cases or 39.3%) and most were female (23 cases or 82.1%). The most common proteinuria level found was +3 (8 cases or 28.6%) and the most common histopathological class was class IV (13 cases or 46.4%). Chi square test showed no significant relationship between proteinuria level and LN histopathological class (p=0.069) nor between age and LN histopathological class (p=0.202). It was concluded that LN patients at Sanglah Hospital in 2016-2020 were mostly women, aged 26-35 years, with a proteinuria level of +3 and included class IV LN. Since there is no correlation between age or proteinuria level with histopathological class, it is recommended that histopathological biopsy be performed in all cases of suspected LN so that patients receive adequate therapy based on the level of kidney damage.

Keywords : Lupus nephritis, age, gender, proteinuria level, histopathological class according to ISN/RPS
Efektivitas Kombinasi Masasse Effluerage dan Deep Back Masasse Terhadap Penurunan Nyeri Persalinan Kala I Fase Aktif
Authors: Darma Ika Yulia , Zaimy Silvi
Published: January 2024

Latar Belakang : .Menjelang persalinan, ibu hamil akan merasakan nyeri akibat kontraksi rahim yang semakin lama semakin kuat. Sebagian ibu ada yang bisa tahan dengan nyeri persalinan, namun ada pula ibu bersalin yang merasa sangat kesakitan saat persalinan. Masasse effluerage dan deep back masasse salah satu alternatif non farmakologi yang yang dapat digunakan dalam intervensi  manajemen nyeri ibu bersalin yang mudah diaplikasikan.

Tujuan :memaparkan efektifitas kombinasi masasse effluerage dan deep back masasse terhadap penurunan nyeri persalinan.

Metode Penelitian :Jenis penelitian Quasy Experimental dengan rancangan one group pretest and posttest design. Sebanyak 24 ibu bersalin kala I fase aktif dengantingkat  nyeri sedang - berat dipilih dengan metode purposive sample untuk studi ini, dikelompokan sebagai berikut kelompok kombinasi, kelompok dengan masasse effluerage dan kelompok deep back masasse. Penelitian ini dilakukan di PMB Sariguti,  PMB Harti candra dan PMB Nurhaida.

Hasil : Setelah dilakukan intervensi kelompok kombinasi terbukti efektif terhadap nyeri persalinan dengan nilai rerata lebih tinggi dibandingkan kelompok masasse efluerage dan kelompok deep back masasse, secara statistik deskriptif diperoleh rerata penurunan nyeri sebesar 3,66 ± 0,516 dengan signifikansi p value 0,000 ( p < 0,05).

Kesimpulan : kombinasi metode masasse effluerage dan kelompok deep back masasse efektif terhadap penurunan nyeri ibu bersalin. Intervensi ini dapat digunakan sebagai penatalaksanaan manajemen nyeri ibu bersalin di praktik bidan mandiri maupun di klinik bersalin.

Kata kunci :  Masasse Effluerage , Deep Back Masasse, Nyeri Persalinan
KARAKTERISTIK KLINIKOPATOLOGI PENYAKIT HIRSCHSPRUNG DI RSUP SANGLAH DENPASAR TAHUN 2019-2020
Authors: Wilananda Ida Bagus Ardya Kurnia , Dewi I Gusti Ayu Sri Mahendra , Winari Ni Wayan , Sriwidyani Ni Putu
Published: January 2024

ABSTRACT

 

Hirschsprung's disease is an abnormal condition of the colon with characteristics of the Meissneri submucosus, myenteric plexus and Aurbachi plexus without parasympathetic ganglion cells. Manifestations of Hirschsprung's disease are seen in the discharge of meconium that does not come out within 24 hours. Then there are signs of obstruction to the gastrointestinal tract, vomiting bile, constipation, and irregular bowel movements. In 2017, 2.5 million children died in the first month of life worldwide. 47% of deaths of children under the age of 5 years occur in newborns, which is about 7,000 deaths. Cases of Hirschsprung's disease itself occur in 1:5000-7000 births, with cases in boys 4 times more than girls. This study aims to determine the clinicopathological characteristics of Hirschsprung's disease at Sanglah Hospital Denpasar in 2019-2020 based on clinical symptoms, age, gender, and location of the aganglionic bowel segment.

This study was carried out in 2021 at the Sanglah Hospital Denpasar Anatomical Pathology (PA) installation, using data from the years 2019-2020. It was conducted using a cross-sectional method, with secondary data in the form of patient data available at the Sanglah Hospital Denpasar PA Laboratory, and total sampling. SPSS version 26 was used to analyze the data.

The results of this study showed that there were 78 patients with Hirschsprung's disease at Sanglah Hospital Denpasar in 2019-2020 and all of them met the criteria of inclusion. Most cases of Hirschsprung's disease in Sanglah Hospital Denpasar experienced the most flatulence, namely 38 cases with a percentage of 36.5%. Cases were dominated by patients within age of 0-12 months with total of 64 people with 82.1% percentage, and dominated by men as many as 50 people with 64.1% percentage. The aganglionic most frequently found in the rectum as many as 49 people with a percentage of 62.8%.

It was concluded from the study result that Hirschsprung's disease patients at Sanglah Hospital in 2019-2020 were mostly male, mostly in the age range 0-12 months, with the most clinical symptoms being flatulence, and the most common aganglionic location found in the rectum. This result may then be used as a basis and also study material for further related research and learning

Keywords : Hirschsprung's disease, congenital megacolon, aganglionic, clinicopathological characteristics
Angka kejadian nyeri kepala pasca anestesia spinal pada pasien paskaoperasi seksio sesarea
Authors: Parami Pontisomaya , Wiryana Made , Senapathi Tjokorda Gde Agung , Ryalino Christopher , Pradhana Adinda Putra , Narakusuma I Putu Fajar
Published: January 2024

Nyeri kepala pasca anestesia spinal merupakan salah satu resiko dari anestesi neuraksial yang terjadi setelah prosedur anestesi spinal akibat tusukan dural atau robekan selama dilakukannya anestesi yang dapat disertai dengan gejala mual, muntah, serta gangguan pendengaran dan penglihatan. Tujuan penelitian ini adalah untuk melihat angka kejadian nyeri kepala pasca spinal anestesia pada pasien pasca operasi seksio sesarea di RSUP Sanglah Denpasar. Penelitian ini merupakan penelitian deskriptif potong lintang yang dilakukan terhadap semua pasien yang menjalani operasi dengan teknik anestesia spinal di RSUP Sanglah Denpasar selama periode tiga bulan di tahun 2021. Sebanyak tiga sampel dieksklusi karena sebelumnya telah memiliki riwayat nyeri kepala, sehingga diperoleh total 109 sampel. Kuisioner diisi sesuai jawaban responden pada hari ke-2 dan ke-5 paskaoperasi. Hasil penelitian menunjukkan angka kejadian nyeri kepala pasca anestesia spinal pada hari kedua dan hari kelima paskaoperasi adalah sama yaitu sebesar 2%, seluruhnya merupakan nyeri kepala dengan derajat ringan.
FAKTOR TERJADINYA HEMORRHOID DI RUMAH SAKIT UMUM PUSAT SANGLAH DENPASAR BALI TAHUN 2020
Authors: Surya Maria Angeline Ivana , Sueta Made Agus Dwianthara , Mahayasa Made , Mulyawan Made
Published: January 2024

Hemoroid adalah dilatasi varikosus vena atau pelebaran pembuluh darah vena dari pleksus hemorrhoidal inferior dan superior, dikarenakan peningkatan tekanan pembuluh vena. Kondisi ini menyerang kurang lebih 30 dari 52% orang dewasa di dunia. Penyebab dari hemorrhoid ini sendiri masih idiopathic atau belum banyak diketahui, tapi banyak faktor yang diduga menjadi risiko terjadinya hemoroid seperti umur, jenis kelamin, riwayat keluarga, kurangnya konsumsi serat, konstipasi, dan overweight.  Sedangkan untuk penelitian mengenai faktor risiko kejadian hemorrhoid di Bali masih sangat terbatas, terutama pada RSUP Sanglah Denpasar, sehingga belum ditemukan faktor risiko dominan tentang terjadinya hemorrhoid atau wasir tersebut. Sehingga, penelitian ini bertujuan untuk mengetahui faktor terjadinya hemoroid pada RSUP Sanglah Denpasar tahun 2020. Penelitian ini merupakan penelitian analitik observasional dengan desain cross sectional. Teknik pengumpulan data dilakukan dengan consecutive sampling yaitu cara pengambilan sampel dimana semua subjek datang pada jangka waktu tertentu dan memenuhi kriteria pemilihan dimasukkan dalam penelitian sampai besar sampel yang diperlukan terpenuhi. Terdapat 50 data penelitian yang terkumpul dengan 29 data dari pasien hemoroid dan 21 data dari pasien bukan hemoroid yang dirawat di poli bedah digestif RSUP sanglah Denpasar pada tahun 2020. Hasil dari penelitian ini adalah ditemukan adanya hubungan yang signifikan antara kurangnya konsumsi serat (PR= 1,75; 95% CI 3,61(1,11-11,76); P=0,03), konstipasi (PR= 1,80; 95% CI 4,53 (1,30-15,77); P= 0,014), dan overweight (PR= 1,7; 95% CI 3,94 (1,14-13,65); P=0,027) dengan kejadian hemoroid dan tidak terdapat hubungan antara usia (PR= 0,89; 95% CI 0,76 (0,24 – 2,38); P= 0.634), jenis kelamin (PR= 1,01; 95% CI 1,03 (0,33 – 3,16); P=0,963), dan riwayat keluarga (PR= 1,44; 95% CI 3,2 ( 0,33-30,94 ); P= 0,293) dengan kejadian hemoroid di RSUP Sanglah Denpasar tahun 2020. Selanjutnya Berdasarkan analisa untuk melihat kekuatan hubungan masing-masing faktor resiko dengan kejadian Hemoroid, dengan menggunakan analisa multivariat regresi logistik, didapatkan penderita dengan konstipasi memiliki hubungan yang paling kuat dengan kejadian Hemoroid (p=0,028, 95% CI = 1,19 – 22,92).
ANGKA KEJADIAN ACUTE KIDNEY INJURY PADA KEHAMILAN: NARRATIVE REVIEW
Authors: Malau Saranitha Windy Oktavia
Published: January 2024

Incidence of acute kidney injury (AKI) in pregnancy still plays an important role in maternal and fetal morbidity and mortality. However, in some developing countries the maternal and fetal mortality rates have started to decline and are still increasing in developed countries. This study was conducted to determine the incidence of AKI in pregnancy in several countries. This study was to determine incidence of AKI in pregnancy using a narrative review research model, in which a worldwide literature search was carried out through the e-library, such as pubmed and proquest which discusses the incidence of AKI in pregnancy. After the journals that match the inclusion criteria are collected, they are analyzed and interpreted in a narrative form. There were 10 journals that matched the inclusion criteria by including the total number of samples and the number of new samples, where the incidence of AKI in pregnancy was found in American countries, China, Indian countries and African countries. Based on this study, the range of incidence of acute kidney injury in pregnancy from several countries was 0.07% to 8.1%. The incidence rate in the American countries began to decline by 6.15% to 0.08%, but based on the average it still increased from 0.04% to 0.12%. In China, it was found 0.81% to 3.68%, Indian countries 2.78% to 0.07%, and African countries 8.1% to 2.29%.

Keywords : Incidence, Acute Kidney Injury in pregnancy, Complications in pregnancy
ANALYSIS OF FACTORS AFFECTING QUALITY OF LIFE OF HEAD AND NECK CANCER PATIENTS IN SANGLAH HOSPITAL
Authors: Nirmala Made Sinta Ayu Suci , Tusta Adiputra Putu Anda , Setiawan I Gede Budhi , Yuniawaty Wetan Ni Gusti Ayu Agung Manik
Published: January 2024

Head and neck cancer ranked as the fifth most common cancer in the world. A series of treatment is likely to cause changes in the quality of life in cancer patients. This study aims to determine the factors that affect the patient's quality of life and the relationship between EORTC QLQ-H&N35 and Karnofsky Performance Scale (KPS). This study is analytic with a cross sectional approach. The technique is total sampling adjusted to the inclusion and exclusion criteria. Data obtained were gender, age, anatomical location of head and neck cancer, stage of cancer, therapy, KPS, and EORTC QLQ-H&N35. Data was collected for 3 months and 45 samples were obtained. There were 24 patients ((53.3%) above 45 years old. 33 men (73.3%) and 12 women (26.7%). The most cases were nasopharyngeal cancer is 25 people (55.6%). A total of 19 patients (42.2%) were in stage IV. The most used therapies were surgery, chemotherapy, and radiotherapy is 19 people (41.3%). The mean KPS is 72.23 ± 16.992. The factor affect the quality of life of head and neck cancer patients the most is weight loss with a mean of 59.49 ± 49.989 and a significant correlation (p=0.000, p<0.05) between EORTC QLQ-H&N35 and KPS.
THE CORRELATOIN BETWEEN KNOWLEDGE AND ECONOMIC LEVELS WITH HIV/AIDS TRANSMISSION PREVENTION BEHAVIOR ON HOUSEWIVES IN MERSI VILLAGE, PURWOKERTO TIMUR SUB-DISTRICT, BANYUMAS REGENCY
Authors: Dwindani Assyifa Tashya , Putri Prima Maharani , Nitiprodjo Abdul Hakim , Kusumawati Anis
Published: January 2024

ABSTRACT

Background : HIV is still an epidemic for several countries in the world, including Indonesia. The percentage of HIV positive women in Central Java in 2019 was quite high (33.7%) including housewives. Transmission of HIV/AIDS to housewives can occur due to lack of knowledge related to HIV/AIDS. The level of the economy plays a role in influencing a person's behavior in preventing the transmission of HIV/AIDS. Data from the Banyumas Health Office in 2021, reported that there were 62 cases of HIV/AIDS in Banyumas. One of the areas with high HIV/AIDS cases is the Mersi Village area.

Objective : This study aimed to determine the correlation between knowledge and economic levels with HIV/AIDS transmission prevention behavior among housewives in Mersi Village, Purwokerto Timur Sub-district, Banyumas Regency.

Methods : The study was an analytic-observational study with a cross-sectional approach. Chi-square test and multivariate logistic regression test were utilized to see the bivariate statistical test.

Result : Bivariate analysis between knowledge level and HIV/AIDS transmission prevention behavior obtained p value = 0.002 and analysis between economic level and HIV/AIDS transmission prevention behavior obtained p value = <0.001, which meant the p value <0.05 and indicates H1 is acceptable.

Conclusion : There is correlation between knowledge and economic levels with the behavior of preventing HIV/AIDS transmission among housewives in Mersi Village, Purwokerto Timur Sub-district, Banyumas Regency.

Keywords : knowledge, economy, prevention behavior, HIV/AIDS
TINGKAT PENGETAHUAN PADA KECEMASAN REMAJA TERHADAP COVID-19 DI SMPN 16 KERINCI
Authors: Sari Putri Minas , Nur Siti Aisyah , Diana Morika Honesty , Idaman Meldafia
Published: January 2024

Covid-19 has become a worldwide pandemic disease. In Indonesia, every year the anxiety rate continues to increase, estimated at 20% of the world's population and as many as 47.7% of adolescents feel anxious. The purpose of the study was to determine the relationship between knowledge levels and anxiety levels against covid 19 in adolescents at SMPN 16 Kerinci. This type of research is descriptive-analytic with a cross-sectional design. The research was conducted at SMPN 16 Kerinci on June 22, 2021. The study population was all students of grades VII and VIII at SMPN 16 Kerinci using proportional random sampling techniques. Data collection using questionnaires was analyzed through univariate and bivariate analysis. The results showed that adolescents whose knowledge level was sufficient and moderate had the same value, which was 34% and the level of moderate anxiety and no symptoms had the same value, which was 34%. The results of the Chi-square test found a relationship between the level of knowledge and the level of anxiety about Covid-19 in adolescents at SMPN 16 Kerinci (p-value 0.019 < 0.05). The results of the study concluded that there is a relationship between the level of knowledge and the level of anxiety about Covid-19, it is hoped that the principle of SMPN 16 Kerinci can form a Covid-19 task force team in schools to be more vigilant about Covid-19.