bluuebunny/crossref_metadata_2025 huggingface dataset:
Os direitos da saúde da população negra: enfoque no atendimento na atenção primária à saúde primária para este grupo étnico/social
Authors: Alves Vinicius de Carvalho Siqueira , Silva Gregson Luís Matos , Torres Pedro Henrique de Castro , Oliveira Guilherme Ribeiro Farias de , Branco Pedro Henrique Brandão Castelo , Rocha Isabella Arce Leite , Martins Neto José Ribamar , Oliveira Ian Farias de , Babani Bhav , Alves Rosemary Amanda Lima , Martins Fabiana Mânica
Published: January 2025

Introdução: Este estudo analisa as barreiras estruturais e institucionais que comprometem o Sistema Único de Saúde (SUS) na garantia de integralidade e equidade no atendimento à população negra no Brasil. Apesar da Política Nacional de Saúde Integral da População Negra, sua implementação é insuficiente diante dos desafios impostos pelo racismo estrutural e institucional. A população negra enfrenta os piores indicadores socioeconômicos e de saúde, agravados por práticas discriminatórias nos serviços de saúde. Metodologia: a pesquisa foi conduzida por meio de uma revisão da literatura de publicações entre 2009 e 2023, utilizando descritores relacionados à saúde da população negra e ao racismo institucional, selecionando inicialmente 23 artigos que depois de triados pelos critérios de inclusão e exclusão, totalizaram 18 para o estudo. Resultados e Discussão: Os resultados indicam que o racismo institucional se manifesta por atitudes discriminatórias, negligência e barreiras ao acesso aos serviços de saúde. Essas práticas perpetuam desigualdades, impactando negativamente a saúde da população negra, com consequências psicossociais como sofrimento mental e exclusão. Casos de violência obstétrica e dificuldades no cuidado reprodutivo contra mulheres negras foram destacados, evidenciando a incapacidade do SUS de cumprir seus princípios de equidade e integralidade. O fortalecimento de políticas públicas, o monitoramento de indicadores de saúde específicos e a capacitação profissional são fundamentais para combater essas desigualdades e promover práticas antirracistas.Conclusão: Avaliação das disparidades indica que o racismo estrutural e institucional ainda representa um obstáculo relevante para a concretização dos princípios do SUS. Logo, a fim de superar essas dificuldades, é fundamental aprimorar o acompanhamento de indicadores de saúde, aprimorar a capacitação de profissionais e estabelecer iniciativas mais efetivas no combate ao racismo.
A importância da atenção primária na formação médica: um relato de experiência na UBS Vila da Prata, Manaus
Authors: Martins Eduarda Pereira , Mesquita Anna Kássia Guimarães de , Mesquita Anna Rafaella Guimarães de , Nunes José Eduardo Pará , Maia Camila Eduarda Câmara , Araújo Ana Carolina Fonseca de , Lira Maria Clara Loiola de , Matos Luana Violeta Rodrigues de , Perez Julia Evan Mendes , Martins Fabiana Mânica , Espir Thaís Tibery
Published: January 2025

Este artigo apresenta as vivências práticas realizadas na Unidade Básica de Saúde (UBS) Vila da Prata, em Manaus, como parte da disciplina "Saúde Coletiva III" do curso de Medicina da Universidade Federal do Amazonas (UFAM). No período de outubro a novembro de 2024, os estudantes participaram de atividades semanais em diferentes setores da atenção básica, incluindo farmácia, triagem, vacinação, consultórios médicos e de enfermagem, além de ações no SISREG e na coleta de exames laboratoriais. Essas experiências foram complementadas por visitas domiciliares, realizadas em parceria com agentes comunitários de saúde, e por atividades educativas, como palestras na campanha Novembro Azul e ações de vacinação em escolas. O contato próximo com a comunidade permitiu vivenciar os desafios e potencialidades da atenção primária, destacando a importância do vínculo, da humanização e da interdisciplinaridade no cuidado à saúde. As experiências reforçaram o papel transformador da formação médica voltada para o SUS e para as necessidades da população.
Impactos do uso de antibióticos nos períodos perinatal e neonatal sobre a microbiota intestinal e a saúde da criança a longo prazo
Authors: Serikava Nicole Tie Furrier , Viana Giovana Santos , Vaquero Emily Cabral , Colomietz Isabella Ferreira , Oliveira Gabrielli Moreno de , Rafael Benício Bonatelli  , Carvalho Alícia de Alencar , Kairala Andrea Lopes Ramires
Published: January 2025

Introdução: Mais de 70% dos pacientes no período perinatal, sob cuidados em Unidades de Terapia Intensivos Neonatal (UTIN), recebem a administração de antibioticoterapia. Entre os efeitos adversos, destaca-se a capacidade dos antibióticos de prejudicar os mecanismos de defesa e causar danos ao organismo, resultantes da redução das funções e da alteração da composição da microbiota intestinal. Metodologia: Trata-se de uma revisão de literatura, utilizando-se os descritores “Anti-Bacterial Agents AND Newborn AND Gastrointestinal Microbiome”, sendo selecionados 10 (dez) trabalhos datados de 2017 a 2023, nos idiomas inglês, espanhol e português. Discussão: A diversidade da microbiota intestinal em desenvolvimento inicial depende da exposição repetida a novos antígenos bacterianos para a sua maturação imunológica. Com isso, o tratamento com antibióticos é considerado um fator de risco para o desenvolvimento de diversidade microbiana no início da vida, com o potencial de desenvolvimento imunológico alterado, impactando na diversidade de espécies e a função da microbiota gastrointestinal. Conclusão: Destaca-se a complexa interação entre a microbiota intestinal, o uso de antibióticos e a saúde geral ao longo da vida. Ademais, a discussão sublinha a necessidade urgente de uma abordagem mais criteriosa no uso de antibióticos, especialmente em populações vulneráveis, como recém-nascidos e gestantes.
Do nacional ao local: abrindo a caixa preta da (não) inclusão dos catadores de materiais recicláveis nos planos municipais de gestão integrada de resíduos sólidos
Authors: Conceição Priscila Soraia da , Rutkowski Emília Wanda , Rezende Sonaly
Published: January 2025

A complexidade de converter opções políticas em estratégias social, econômica e ambientalmente aceitáveis coloca os catadores de materiais recicláveis e os desafios que vivenciam na agenda das pesquisas em ciência, tecnologia e sociedade. Este trabalho tem como objetivo buscar elementos que subsidiem a interpretação de como se dá a presença dos catadores na gestão de resíduos sólidos em uma escala regional, por meio da análise de planos municipais de gestão de resíduos sólidos (PMGIRS). Optou-se por realizar a discussão a partir de um estudo empírico aplicado ao Comitê da Bacia Hidrográfica dos Rios Sorocaba e Médio Tietê. O percurso metodológico se deu pela Grounded Theory e a técnica aplicada foi a análise dos PMGIRS dos municípios que compõem a bacia em estudo. Os resultados encontrados foram explicados por meio dos conceitos derivados da Teoria Ator-Rede. A análise revelou a importância das diretrizes dos planos municipais para o alcance de metas de universalização, porém, mediante o conteúdo que abordam, são incapazes de traduzir os interesses da Lei Federal no 12.305/2010 quanto à inclusão de catadores. Deste modo, conclui-se que é essencial a adoção de estratégias mais eficientes para o controle a longa distância, alinhando interesse dos Governos Federal e Municipal.
Training and development opportunities for medical writers from different regions across the world
Authors: Guillemard Michelle , Howson Alexandra , Zhang Ann
Published: January 2025

In the dynamic and rapidly evolving field of medical writing, continuous learning and professional development are crucial for success. Medical writers play a vital role in translating complex scientific and medical information into clear, accurate, and engaging content for various audiences, including healthcare professionals, regulatory bodies, and the general public. To excel in this demanding profession, medical writers must stay updated with the latest advancements, writing techniques, and industry best practices. Fortunately, there are many training and development opportunities available worldwide tailored specifically for medical writers. This article delves into the various training possibilities available globally, from short courses to education programmes and from certification courses to workshops, conferences and online resources, providing a useful guide for medical writers eager to enhance their skills and advance their careers.
Saving the planet, one EMWA conference at a time
Authors: Jacobs Adam
Published: January 2025

I had been a frequent business traveller for some years until not so long ago. Most of my trips were by plane. I would typically fly to some destination or other most months. Then COVID came along, and in March 2020, business travel suddenly stopped. It took a while to get going again, and my first international journey after that was to the EMWA conference in Berlin in May 2022. Having had that little break from travel was no bad thing, as it gave me the chance to pause and reflect on my travelling, and, in particular, on the climate impact of air travel.
Mastering the art of the state of the art (under EU MDR 2017/745)
Authors: Jumelle Clotilde
Published: January 2025

Establishing the state-of-the-art (SOTA) represents a crucial aspect of a clinical evaluation under the European Medical Device Regulation (EU MDR) 2017/745. In this article, I share my experience of working on SOTA documents over the last four years. It first briefly recapitulates the SOTA requirements of the EU MDR (that are in fact almost non-existent) followed by the different steps required to conduct and document the literature search. Also included are some tips and tricks on structuring the SOTA. Finally, advantages and limitations of different scientific literature databases are provided.
Comprehensive evaluation method for site selection of CO2 geological sequestration in injection-level reservoirs
Authors: Liu Wenkai , Wang Sen
Published: January 2025

Geological sequestration of CO2 is a crucial means of reducing CO2 emissions. China in CO2 sequestration have commenced relatively late, and both site selection criteria and evaluation methods require further refinement. Primary sequestration sites for CO2 include reservoirs, coal seams, and deep saline formations. Among these, reservoirs serve as sequestration sites due to their favorable geological conditions, high degree of exploration, and potential for economic benefits. Currently, China categorizes sequestration sites into five levels: regional, basin, target area, site, and injection. This paper proposes a site selection and evaluation methodology specifically for the injection level. Firstly, a prediction model for the geological sequestration potential of CO2 in reservoirs is established based on machine learning methods. Subsequently, an evaluation index system is constructed based on three categories of indicators: safety, potential, and economy, the evaluation thresholds for potential indicators were determined using a potential evaluation model, while the evaluation thresholds for safety and economic indicators were established through methods such as factor analysis. Finally, a comprehensive evaluation method for the effectiveness of CO2 sequestration in reservoirs is formulated using the Analytic Hierarchy Process (AHP).
Impacto de la transformación digital en el sector asegurador en Ecuador: Innovación y retos regulatorios
Authors: Zambrano-Noboa Héctor Andrés , Sánchez-Manzaba Solanda Esmeralda , Córdova-Herrera Carlos Vicente , Orellana-Intriago Fernando Rodolfo
Published: January 2025

La transformación digital está redefiniendo las operaciones del sector asegurador en Ecuador, promoviendo la adopción de tecnologías emergentes como el big data, inteligencia artificial y blockchain. Este estudio analiza los beneficios y desafíos asociados a esta transición, con énfasis en la innovación de servicios, la mejora de la experiencia del cliente y los retos regulatorios que enfrenta el país. Utilizando una metodología cualitativa documental, se recopilaron datos a través de una revisión exhaustiva de literatura académica, informes regulatorios y publicaciones especializadas. Los resultados revelan un aumento en la eficiencia operativa, pero también subrayan la necesidad de un marco regulatorio más robusto para mitigar riesgos asociados con la privacidad y seguridad de los datos. Este artículo contribuye al debate sobre cómo equilibrar la innovación tecnológica con una regulación efectiva.
USO INDISCRIMINADO DA AUTOMEDICAÇÃO NO PERÍODO PÓS PANDÊMICO
Authors: Cunha Tayana Conde da , Barbalho Jordão Carvalho e , Silva Augusto César Vasconcelos Coelho da , Araujo Matheus Neves , Lobo Vanessa Santana , Ribeiro Italo Santos dos Remédios , Lopes Angélica Silva Varão , Catarino Patrícia Carla Guimarães , Gomes Raylane de Souza Silva , Branco Felipe Dominici Castelo
Published: January 2025

Este estudo analisa as consequências do uso indiscriminado da automedicação no período pós-pandêmico, uma prática exacerbada durante a pandemia de COVID-19. Com o objetivo de identificar os fatores que influenciaram o aumento da automedicação e avaliar suas implicações para a saúde pública. Trata-se de uma revisão integrativa, selecionando artigos das bases de dados PubMed, Lilacs e Scopus, nos idiomas inglês, português e espanhol no período de 2018-2024. A automedicação foi identificada em 100% dos artigos, com 80% relatando prevalência significativa e ampla variação, com aumento durante a pandemia de COVID-19 em 50% dos estudos, destacando o uso de analgésicos, antipiréticos, antibióticos e fitoterápicos, mesmo sem evidências claras e destacaram os riscos associados, como aumento transtornos psicológicos e de resistência antimicrobiana. A análise comparativa com dados da Organização Mundial da Saúde (OMS) e do Ministério da Saúde do Brasil confirmou o impacto global dessa prática, especialmente em áreas com acesso limitado a cuidados de saúde. Conclui-se que há uma necessidade urgente de políticas de saúde pública que restrinjam o acesso indiscriminado a medicamentos e promovam campanhas educativas para conscientizar a população sobre os riscos da automedicação, visando mitigar suas consequências para a saúde pública.
CYBER SEXUAL HARASSMENT DALAM APLIKASI BUMBLE DAN HUBUNGANNYA DENGAN CITRA TUBUH PADA WANITA
Authors: Setiawan Talitha Azalia , Majorsy Ursa
Published: January 2025

Di tengah era digital, pelecehan seksual masih tetap ada dan bertransformasi menjadi cyber sexual harassment. Cyber sexual harassment berpotensi untuk mengubah citra tubuh para korbannya, terutama wanita. Citra tubuh merupakan evaluasi, persepsi, pikiran, perasaan, pendapat, maupun penghormatan tentang ukuran, bentuk, dan wujud tubuh seseorang. Penelitian ini bertujuan untuk mengetahui hubungan cyber sexual harassment dan citra tubuh pada wanita pengguna aplikasi Bumble. Metode yang digunakan dalam penelitian ini adalah metode kuantitatif dengan teknik analisis korelasi sederhana produk momen dari Carl Pearson. Sampel dalam penelitian ini adalah 121 wanita pengguna aplikasi Bumble berusia 18-35 tahun yang dipilih dengan menggunakan teknik purposive sampling. Pengukuran cyber sexual harassment menggunakan Cyber-Sexual Experiences Questionnare (CSEQ) oleh Schenk (2008) dan pengukuran citra tubuh menggunakan Body Appreciation Scale (BAS) oleh Avalos, dkk. (2005). Hasil uji hipotesis menunjukkan nilai signifikansi sebesar 0,011 dan nilai korelasi sebesar -0,230. Hal ini memperlihatkan bahwa terdapat hubungan dalam bentuk negatif cyber sexual harassment dan citra tubuh pada wanita pengguna aplikasi Bumble. Semakin rendah cyber sexual harassment individu, maka semakin tinggi citra tubuh yang dimiliki individu tersebut, dan sebaliknya. Penelitian ini menunjukkan cyber sexual harassment yang berada pada kategori rendah dan citra tubuh yang berada pada kategori tinggi.
Inteligencia artificial
Authors: López-Martínez Rocío Edith
Published: January 2025

El uso de la inteligencia artificial (IA) en el ámbito educativo transformó el quehacer docente. Esta investigación utilizó un enfoque mixto con el fin de explorar el impacto de la IA en las actividades que realizan los docentes mediante cinco vectores: el dominio IA, la comunicación, el uso y técnicas, las habilidades, la eficiencia y la eficacia de la IA. Para recolectar los datos se aplicó una encuesta a 37 docentes de posgrado de la Facultad de Informática de la Universidad Autónoma de Querétaro (UAQ), México. Los resultados señalaron que los maestros que hacen uso de IA cuentan con herramientas que mejoran la eficiencia educativa. Por otro lado, se identificaron varios desafíos y cuestiones éticas que son importantes trabajar en la UAQ. Asimismo, la investigación destacó la relevancia de utilizar IA en la educación y generó una base sólida para futuras investigaciones. Por lo tanto, los profesores deben adquirir habilidades y conocimientos específicos para diseñar y utilizar herramientas de IA de manera efectiva.
HIGH MOLECULAR MASS ANTIGENIC COMPONENTS OF PARACOCCIDIOIDES BRASILIENSIS: PARTIAL CHARACTERIZATION AND IMPLICATIONS IN THE TH1 RESPONSE
Authors: Kaminami Mari Sumigawa , Vidal Adriane Lenhard , Souza Bianca Dorana de Oliveira , Itano Flávio Hiroshi , Ono Mario Augusto , Chiyoda-Rodini Franciele Ayumi Semencio , Suguiura Igor Massahiro de Souza , Sano Ayako , Itano Eiko Nakagawa
Published: January 2025

Paracoccidioidomycosis (PCM) is a chronic infection caused by the fungi Paracoccidioides brasiliensis or P. lutzii, whose host defense is mediated by Th1 lymphocytes. This study aimed to purify and evaluate the effect of high molecular mass (hMM) components of P. brasiliensis on the cellular immune response. The soluble antigens of the fungus (Pb18) were subjected to chromatography on a Sephadex G-200 column followed by HPLC, obtaining the fraction F17 (~380 kDa) and its subfraction F17-IV (~70 kDa), both reactive to sera from patients with PCM. The fractions were tested in vitro with splenic cells from infected mice, resulting in a lymphoproliferative response and increased levels of INF-γ and IL-10, without alteration of IL-4. These findings indicate the activation of the Th1 immune response and suggest that the ~380 kDa fraction can degrade to generate active subcomponents of ~70 kDa. The ~70 kDa subcomponent appears to be distinct from the gp70 described in the literature, given its ability to induce INF-γ. The results indicate the immunogenic potential of these components, highlighting their relevance for the development of vaccines or therapies against PCM.
DIAGNOSTIC CHALLENGES OF EVALI: A REVIEW OF RADIOLOGICAL AND TOMOGRAPHIC FINDINGS IN ELECTRONIC CIGARETTE USERS
Authors: Corrêa Hugo Leonardo Cinél , Durand Marina de Toledo , Regueiro Eloisa Maria Gatti
Published: January 2025

This study aims to examine the specific findings of imaging studies, such as radiographs and computed tomography (CT), in patients with E-cigarette or Vaping Product Use-Associated Lung Injury (EVALI). The use of electronic cigarettes (EC), also known as vaporizers, has increased significantly in recent years, particularly among young individuals and adults, due to the perception of them as safer alternatives to traditional cigarettes. However, increasing evidence suggests potential lung damage, leading to the recognition of EVALI as a respiratory condition. This pathology presents a significant diagnostic challenge due to the wide range of clinical and imaging findings that often resemble other respiratory conditions. Given this scenario, a comprehensive review of clinical cases and studies published in the CAPES Periodical Portal and PubMed databases was performed in order to identify specific patterns and characteristics in radiographs and CT, providing a more comprehensive understanding of the symptoms of EVALI and contributing to the early diagnosis and treatment of these patients.
Incidence of virtual education in front of covid-19 in the tilipulo neighborhood during the school year 2020- 2021
Authors: Moreno Muso Nasheli Estefanía
Published: January 2025

In 2020, Ecuador faced significant challenges due to the impact of COVID-19, which forced the government to suspend face-to-face activities, including classes, and implement virtual education as an alternative. This abrupt change evidenced technological, economic and social barriers, especially in rural areas such as the Tilipulo neighborhood in Cotopaxi province. Only 37% of Ecuadorian households had internet connection, while in rural areas this access was reduced to 16%, which led to a high student dropout rate.Students faced difficulties related to connectivity, lack of technological devices and the instability of internet service, factors that limited the effectiveness of virtual learning. According to the surveys conducted, 50% of the students did not attend classes regularly due to these problems, and 58% knew someone who had dropped out of school.Despite these limitations, e-learning helped protect the health of students and their families by preventing the spread of the virus. However, it did not guarantee meaningful learning, as many students lacked knowledge about the use of digital platforms.The study concluded that, although virtual education was a solution to the pandemic, it revealed structural inequalities in access to technological and educational resources in Ecuador, highlighting the need to implement strategies to improve the quality of and access to virtual education in the future
Immersive versus conventional technologies in neuroanatomy teaching
Authors: Priego Álvarez Heberto Romeo , Córdova Hernández Juan Antonio , Lizcano Sánchez Miguel , Camacho Ramos Ricardo Humberto , Cornelio Ferrer Yuliana Esther , Fernández Quintana Querubín
Published: January 2025

Introduction: The study of immersive technologies in education has gained relevance due to its potential to improve learning. Objective: Compare the perceptions of two groups of students about immersive and traditional learning methods, with the intention of identifying the advantages and disadvantages of each approach. Method: A prospective cross-sectional quantitative correlational investigation was carried out. The non-probabilistic sample included 56 students of the degree in Medical Surgeon of the Juárez Autonomous University of Tabasco (UJAT), enrolled in the February-August 2024 school year. Two groups of 28 students were considered: one with traditional learning and the other with immersive learning. Structured questionnaires were used to assess information retention, participation, and application of knowledge in simulated clinical scenarios. Results: The traditional group considered it more important to have a good memory to pass (46.43% vs. 39.29% in Group H) and felt that teachers paid more attention to the memorized information. The Immersive group reported less pressure on the quality of work (39.29%) but also perceived a greater workload (39.29%). Both groups mentioned teachers' lack of interest in listening to student opinions and had a mixed perception about understanding the course objectives. There were significant associations between good teaching, clear objectives, generic skills, independence, and overall course satisfaction. Conclusions: The main challenge for university teachers is to develop programs that integrate immersive technologies, which requires economic investment and greater applied research.
Online Learning Technology: Implications on Mental Health and Learning Outcomes of Students
Authors: Made Abdul Malik , Syahril Syahril , Waskito Waskito , Ranuharja Fadhli , Riyanda Afif Rahman , Sagala Margaretha Karolina , Rinaldi Daniel , Hakim Uswatul , Oluwaseyi Joseph , Torres-Toukoumidis Angel
Published: January 2025

This study examines the impact of online learning on students' mental health and learning outcomes at Batam University, focusing on digital literacy, socio-emotional engagement, digital skills, and the home learning environment. The transition to online learning, driven by the COVID-19 pandemic, has reshaped educational practices, introducing both opportunities and challenges for students. A quantitative approach with an explanatory survey method was adopted to analyze the direct and indirect effects of online learning on mental health and learning outcomes. The study involved 110 Mechanical Engineering students from the 2021, 2022, and 2023 cohorts. Data were collected using a questionnaire with 20 items for each variable, assessed on a Likert scale. Data validity and reliability were tested using SPSS, while path analysis with AMOS was employed to evaluate relationships between variables. The results indicate that online learning significantly affects students' mental health, particularly increasing academic anxiety and stress levels. However, it positively influences learning outcomes, especially in metacognitive skills, though challenges persist in collaborative skills and creativity. Digital skills and the home learning environment are critical factors in achieving successful learning outcomes. This study concludes that while online learning provides flexibility and innovation, it also presents psychological and social challenges. Increasing socio-emotional engagement and adopting a more holistic approach are necessary to mitigate mental health issues and enhance learning outcomes, ensuring that online education supports both the well-being and academic success of students.
Relationship between genes pela and biofilm density in clinical isolates pseudomonas aeruginosa
Authors: Yaultsa Nanda , Wardhani Puspa , Aryati Aryati
Published: January 2025

Introduction: Pseudomonas aeruginosa is a Gram-negative pathogen that causes major infections in patients with weak body defense mechanisms. The pelA gene encodes the Pel polysaccharide for the production of cationic charged polysaccharides, and expression of the polysaccharide-encoding locus (pelA) by Pseudomonas aeruginosa is essential for biofilm formation.Objective: Analyzing the relationship between the pelA gene and biofilm density in clinical isolates of Pseudomonas aeruginosa.Method: Analytical observational research design with consecutive sampling, a total sample of 33 clinical isolates of Pseudomonas aeruginosa. The pelA gene was detected using a PCR tool (SimpliAmpTMThermal Cycler) and biofilm density examination was examined using a BioRad iMark Microplate Reader.Results: Thirty-three clinical isolates of Pseudomonas aeruginosa. In this study, the results of pelA gene detection showed that 31 (93.9%) isolates were positive for the pelA gene and 2 (6.1%) isolates were negative for the pelA gene. The results of the biofilm density examination showed that 4 (12.1%) clinical isolates did not produce biofilm, 10 (30.3%) clinical isolates had weak biofilm production, 13 (39.4%) clinical isolates had moderate biofilm production, 6 (18.2%) isolates had strong biofilm production. The pelA gene has a relationship with biofilm density (p = 0.011) with moderate relationship strength.Conclusion: The pelA gene was moderately associated with biofilm density in clinical isolates of Pseudomonas aeruginosa. This suggests that the pelA gene plays an important role in biofilm formation in Pseudomonas aeruginosa strains which may contribute to its pathogenic properties, especially in patients with weakened immune mechanisms.
The Influence of Brand Ambassador, User Interface and Free Shipping Program on Purchasing Decisions through Tokopedia E-commerce with Brand Trust as an Intervening Variable
Authors: Anindya Annisa , Arslan Rijal , Mendrofa Kristiurman Jaya
Published: January 2025

This study aims to evaluate the influence of Brand Ambassador, User Interface, and Free Shipping Programme on E-Commerce Tokopedia, with Brand Trust acting as an intervening variable. This study employs quantitative approaches and purposive sampling procedures with a sample of 100 respondents. Employing path analysis with Smart PLS version 3 for data analysis. The study's findings demonstrate that brand ambassadors have a favourable and substantial effect on brand trust; nevertheless, their influence on purchasing decisions through Tokopedia is negligible. The user interface has a positive and substantial impact on brand trust and purchasing decisions. The Free Shipping Programme affects brand confidence and purchasing decisions. Brand trust successfully mediates the impact of Brand Ambassador, User Interface, and Free Shipping Programme on purchasing decisions.
Efficacy Teacher In Embedding Discipline Student at Islamic Boarding School
Authors: Runiasih Mawar , Nurhattati Nurhattati , Kamaludin Kamaludin
Published: January 2025

This study aims to determine how much efficacy of Islamic Boarding School teachers in instilling discipline in students is supported by two constructs, namely social support and work engagement. Teacher efficacy is the belief and ability of a teacher in achieving success. One indicator of teacher efficacy is efficacy in discipline. Discipline is an indicator of student success. Therefore, instilling discipline in schools is very necessary to see student learning outcomes. The sample in this study were 32 Islamic Boarding School teachers with Stratified random sampling as a sampling technique. Data collection techniques using a questionnaire with a Likert scale. The data analysis technique in this study used SPSS version 22. The results of this study were for the Social Support (SS) variable to obtain a Chi-Square value of 9.120 with a significance value of 0.000. Work Engagement (WE) obtained a Chi-Square value of 44.970 with a significance value of 0.000. And Teacher Efficacy (TE) obtained a Chi-Square value of 7,179 with a significance value of 0.410.
The Moderating Role of Liquidity in the Relationship between Leverage, Firm Size, and Profitability
Authors: Inrawan Ady , Sembiring Lenny Dermawan , Loist Christine
Published: January 2025

This study aims to analyze the role of liquidity in moderating the effect of capital structure and firm size on profitability. The data used in this research is secondary data from companies in the property and real estate sector listed on the Indonesia Stock Exchange (IDX) for the period 2019–2023. The study employs panel data with a sample of 45 companies selected using purposive sampling, resulting in 225 observations. The analysis uses panel data regression with EViews 13 software, with the best model chosen through the Chow, Hausman, and Lagrange Multiplier tests. The study results indicate that capital structure and liquidity do not significantly affect profitability, while firm size positively affects profitability. Furthermore, liquidity does not moderate the effect of capital structure and firm size on profitability. These findings provide implications for companies and investors in designing strategies and making decisions based on financial analysis to maintain stable financial performance.
Temas Selectos en Oncología Tomo 4
Authors: Espinoza López Susana Elizabeth , Ramírez Verdezoto Luis Ramón , Teruel Leyva Liliana
Published: January 2025

El libro Temas Selectos en Oncología, Tomo 4 es una obra de referencia esencial que aborda los desafíos y avances más recientes en el diagnóstico, tratamiento y manejo multidisciplinario del cáncer. Este tomo, parte de una serie reconocida por su excelencia académica, es ideal para oncólogos, médicos generales, residentes, y profesionales de la salud interesados en mantenerse a la vanguardia en el campo oncológic
Evaluation and Development Trends of Optical Detection Technology for Seed Vigor
Authors: Xiaoyu Wang , Mingdong Zhu , Jie Li , Yu Yang , Hongjun Xie , Yonghong Duan , Nailiang Cao , Ruifeng Kan , Yinghong Yu
Published: January 2025

High-vigor seeds could show superiority in field production because seed vitality is essentially a comprehensive concept composed of germination rate, germination potential, and vitality index. Seed vitality was a traditional method of measurement, albeit a time-consuming and laborious one accompanied by errors caused by human factors. Optical technology had developed rapidly in the agricultural field, making it possible to detect seeds with high precision, high frequency, and high efficiency. In this article, the basic principles, advantages, and limitations of different optical techniques for obtaining seed vigor estimates are introduced and reviewed, and the key technology of non-destructive optical detection of single seeds will be discussed. In addition, the current situation of optical detection nondestructive technology in single seed detection will be discussed and analyzed, and the three directions of optical principle (seed characteristic spectrum database, intelligent sorting, and grading equipment) will be explored, providing a reference for the research methods using optical technology applied to seed detection.
Artificial Intelligence and Originality in Design
Authors: Günay Mustafa
Published: January 2025

The Purpose of the Study: This paper addresses how artificial intelligence (AI) plays a role in the world of design and how it affects the concept of originality. The paper examines the use of AI in areas such as graphic design, logo design, painting, original designs and web design, and discusses the innovations that this technology brings to design processes. The paper also considers the positive and negative effects of AI on designers. Positive effects include the acceleration of design processes and the access to a wider creative spectrum. On the other hand, the impact of AI on originality is a controversial issue. It is questioned how original the designs produced with AI are and whether these designs have artistic value.

Literature Review/Background: The impact of artificial intelligence (AI) technology in the field of design and the reconsideration of the concept of originality are mentioned. While AI offers speed and efficiency in design processes, creative solutions have been addressed through learning from data and algorithms. While the innovations and efficiency advantages offered by AI expand the creative capacities of designers, the concepts of originality and personal expression are evaluated.

Methodology: The research design of the study was qualitative, document scanning method was used as the data collection method, and content analysis method was used to analyse the data. Using the document scanning method, the effects of artificial intelligence in design and the concepts of originality were discussed.

Findings: The impact of artificial intelligence (AI) technology in the field of design necessitates a reconsideration of the concept of originality. While AI offers speed and efficiency in design processes, it produces creative solutions through learning from data and algorithms. However, originality in this process can often be derived from existing data or based on style transfers. While the innovations and efficiency advantages offered by AI expand the creative capacities of designers, it may cause you to question the concepts of originality and personal expression.

Conclusion: the paper suggests that AI is an important tool in the design world and predicts that this technology will become even more widespread in the future. However, it is emphasised that AI should be used carefully and consciously in creative processes.
Evaluación de la atención en niños con parálisis cerebral: Un análisis con la Batería BREV
Authors: Barros Tapia Nestor Rodrigo , Tapia Gonzales Bryam Geovanny , Pacheco González Diana Gabriela , Villalta Chungata Blanca Cecilia , Brito Criollo Tania Alexandra , Yarlequé Brito Diana Maribel , Pintado Quito Andrea Verónica
Published: January 2025

Una de las principales causas de discapacidad infantil es la parálisis cerebral, que genera consecuencias físicas o motoras y cognitivas. Por ello, es fundamental evaluar el estado de las funciones neurocognitivas, particularmente la atención, para diseñar planes de rehabilitación que se ajustan a las necesidades de cada niño. Este estudio tuvo como objetivo determinar el nivel atencional en niños con parálisis cerebral, utilizando la batería BREV como herramienta de evaluación. Se utilizó un enfoque cuantitativo con un alcance descriptivo. Los resultados revelaron que la mayoría de los niños evaluados presentaron grados patológicos en las áreas de atención selectiva y sostenida.
La migración de los jóvenes ecuatorianos hacia los Estados Unidos
Authors: Bustamante Litardo Darling Santiago , Taco Villacís Damián Oswaldo
Published: January 2025

Este estudio exploró las motivaciones que impulsan a los jóvenes ecuatorianos a migrar hacia Estados Unidos. A través de una metodología mixta, se combinó una revisión bibliográfica con una encuesta a jóvenes ecuatorianos. Los resultados revelan que la escasez de empleo, la inestabilidad política y la búsqueda de mejores oportunidades de vida son los principales factores que motivan la migración. Sin embargo, esta decisión también está influenciada por factores sociales, como las redes de apoyo y la percepción de una mejor calidad de vida en Estados Unidos. A pesar de las expectativas positivas, los migrantes enfrentan desafíos en su adaptación, incluyendo dificultades en el ámbito educativo, problemas de salud mental y cambios en su identidad cultural. La investigación concluye que la migración juvenil ecuatoriana es un fenómeno complejo y multidimensional, que requiere de políticas públicas más integrales y enfocadas en las necesidades de los jóvenes migrantes.
LITERATURE REVIEW ON GLUCOSAMINE AND CHONDROITIN IN OSTEOARTHRITIS TREATMENT
Authors:   Vinh Medical University, Nghe An, Vietnam, Thi Soa DANG , Thi Thuy VU ,   Vinh Medical University, Nghe An, Vietnam, Duc Trung NGUYEN ,   Vinh Medical University, Nghe An, Vietnam, Thi Thuc Uyen BIEN ,   Vinh Medical University, Nghe An, Vietnam, Thi Hai Yen LE ,   Vinh Medical University, Nghe An, Vietnam, Trung Hieu TRAN ,   Vinh Medical University, Nghe An, Vietnam, Thao Linh TRAN ,   Vinh Medical University, Nghe An, Vietnam
Published: January 2025

Osteoarthritis is a chronic disease primarily characterized by
articular cartilage damage. In Vietnam, osteoarthritis accounts
for a high percentage of musculoskeletal conditions, especially
affecting the knee joints. Recently, slow-acting anti-
osteoarthritis drugs, including glucosamine, chondroitin
sulfate, and diacerein, have been suggested as key
pharmacological options for treating this condition. However,
Vietnamese-language resources on these active ingredients
remain limited. This article provides a literature review on the
efficacy and safety of these drugs to enhance their effective use
in clinical practice. Results indicate that glucosamine and
chondroitin are both effective and safe for osteoarthritis
treatment, as demonstrated by the data analyzed in this study.
Keywords: Glucosamine; chondroitin; osteoarthritis
ILL-POSEDNESS AND STABILITY ESTIMATE FOR THE HEAT EQUATION BACKWARD IN TIME WITH DIRICHLET AND INTEGRAL BOUNDARY CONDITIONS
Authors:   Department of Mathematics, Vinh University, Nghe An, Vietnam, Van Duc NGUYEN , Hoai Linh PHAN ,   Master's student course 30, Analytical Mathematics, Department of Mathematics, Vinh University, Nghe An, Vietnam
Published: January 2025

In this paper, we first prove that the heat equation backward in
time with Dirichlet and integral boundary conditions is an ill-
posed problem. Then, we establish a stability estimate of Hölder
type for this ill-posed problem.
Keywords: Heat equation backward; ill-posed problem;
stability estimate
SPECIES COMPOSITION AND DENSITY FLUCTUATION OF THE CITRUS LEAFMINER PHYLLOCNISTIS CITRELLA STAINTON (LEPIDOPTERA: PHYLLOCNISTIDAE) ON XOAN ORANGES IN DONG PHU DISTRICT, BINH PHUOC PROVINCE
Authors:   Department of Biology, School of Education, Vinh University, Nghe An, Vietnam, Thi Viet NGUYEN , Thi Hong Thuy DUONG ,   Quang Trung High School for the Gifted, Binh Phuoc, Vietnam, Thi Anh VU ,   Class 62A Biology Pedagogy, School of Education, Vinh University, Nghe An, Vietnam
Published: January 2025

The study on the composition of insect pests on Xoan Orange
trees in Dong Phu District, Binh Phuoc Province, identified 28
species belonging to 25 families and 7 orders. Among these,
the order Hemiptera (true bugs) had the highest number of
species, with 8 species (28.57%), while Lepidoptera (moths
and butterflies) and Diptera (flies) each had only 1 species
(3.57%). Thirteen natural enemy species were recorded,
belonging to 8 families and 4 orders. The order Hymenoptera
(wasps and bees) accounted for the highest number of species
(6 species, 46.16%), while Hemiptera contributed the least (1
species, 7.69%). The density of citrus leafminer (Phyllocnistis
citrella) varied with the season and type of orchard. In
nurseries, the highest density was observed in August
(4.56±0.02 larvae/leaf) and the lowest in January (1.42±0.03
larvae/leaf). In young orchards, the peak density occurred in
April (3.68±0.01 larvae/leaf) and the lowest in January
(1.38±0.02 larvae/leaf). In mature orchards, the highest density
was recorded in April (2.61±0.02 larvae/leaf) and the lowest in
January (0.78±0.04 larvae/leaf). The percentage of damaged
leaves was highest in April across all three orchard types:
Nurseries: 28.55±0.02%; Young orchards: 26.05±0.23%;
Mature orchards: 25.38±0.02%. The lowest damage rates were
observed in January, with corresponding values: Nurseries:
13.59±0.01%; Young orchards: 10.65±0.05%; Mature
orchards: 8.67±0.03%.
Keywords: Citrus leafminer; Phyllocnistis citrella; Xoan Orange
AN EFFICIENT DEPTH-FIRST SEARCH ALGORITHM FOR SOLVING THE MAXIMUM STABLE MARRIAGE PROBLEM WITH TIES AND INCOMPLETE LISTS
Authors:   Institute of Engineering and Technology, Vinh University, Nghe An, Vietnam, Quoc Anh LE , Van Nam DINH ,   Faculty of Pedagogy, Ha Tinh University, Ha Tinh, Vietnam, Huu Viet HOANG ,   Institute of Engineering and Technology, Vinh University, Nghe An, Vietnam
Published: January 2025

This paper proposes an efficient depth-first search algorithm to
solve the maximum stable marriage problem with ties and
incomplete preference lists. The key idea of the algorithm is to
initialize an empty matching and mark all men as unmatched.
In each iteration, an unmatched man proposes to the most
preferred woman on his rank list. If the woman is unmatched
or prefers the proposing man over her current partner, she is
assigned to the man, forming a new pair in the matching.
Otherwise, she keeps her current partner and rejects the
proposing man. When a man is rejected by a woman, he
becomes unmatched. The algorithm then recursively processes
the next unmatched man until it either finds a complete
matching or reaches a predefined maximum number of
iterations. Experimental results on randomly generated
datasets show that our algorithm is effective in producing high-
quality solutions to the problem.
Keywords: Depth-first search; Gale-Shapley algorithm; stable
matching; stable marriage problem; ties and incomplete lists
JOURNALISM IN THE DIGITAL AGE - CHALLENGES AND SOLUTIONS FOR TRAINING WORK
Authors:   Department of Politics and Journalism, School of Social Sciences and Humanities, Vinh University, Nghe An, Vietnam, Thi Phuong Le VU
Published: January 2025

The vigorous development of the Fourth Industrial Revolution has brought
humanity into the digital age. Journalism and journalism training in Vietnam are facing
many new problems; advantages and opportunities are intertwined with difficulties and
challenges. In this article, based on the synthesis of theoretical and practical sources in
Vietnam, we analyze the opportunities that the digital age brings to journalism and also
point out the challenges journalism human resource training faces in the digital age. We
also propose appropriate solutions for journalism human resource training to meet new
requirements in the context of the digital age.
Keywords: Journalism; digital transformation; digital age
OVERVIEW OF RESEARCH ON THE DEVELOPMENT OF SCHOOL COUNSELING COMPETENCIES FOR GENERAL EDUCATION TEACHERS - LESSONS FOR VIETNAM
Authors:   College of Education, Vinh University, Nghe An, Vietnam, Thi Phuong Nhung NGUYEN , Xuan Son PHAM ,   Department of Foreign Language, Vinh University, Nghe An, Vietnam
Published: January 2025

In the context of modern schooling, the role of teachers in
supporting students' mental health has become increasingly
important. This paper reviews studies on developing school
counselling competencies for general education teachers to
draw lessons for Vietnam. Through a literature review
method, the paper analyzes the essential competency
components for counselling work, models, and methods of
developing counselling competencies that have been
applied in various countries. Based on these findings, the
paper recommends designing training programs to enhance
teachers' counselling competencies, contributing to
building a healthy school environment that supports
students' comprehensive psychological development.
Keywords: Psychological counseling; psychological
counseling capacity; psychological counseling capacity
development model.
ГЕНЕТИЧЕСКИЕ И ЭПИГЕНЕТИЧЕСКИЕ ФАКТОРЫ В ГЕНЕЗЕ ВОСПАЛИТЕЛЬНЫХ ЗАБОЛЕВАНИЙ КИШЕЧНИКА
Authors: Богданова Наталья Михайловна , Кравцова Кира Александровна
Published: January 2025

Воспалительные заболевания кишечника (ВЗК) объединяют язвенный колит и болезнь Крона, ко-торые характеризуются хроническим воспалением в гастроинтестинальном тракте. Заболевания имеютмногофакторную этиологию, включая генетическую предрасположенность, микробиоту кишечника, факторы окружающей среды, диету, образ жизни и социально-экономический статус. Во всем мире наблюдается неуклонный рост ВЗК, особенно в странах Скандинавии, Северной Америке, Канаде, Израиле. Вклад диеты в развитие и лечение ВЗК огромен. В 2020 году Европейское общество парентерального и энтерального питания (ESPEN — European Society of Parenteral and Enteral Nutrition) опубликовало рекомендации по диетотерапии при данной патологии и представило информацию о влиянии еды на риск развития данных заболеваний. Показано, что использование молочных продуктов может иметь преимущественно защитный эффект в этиологии как болезни Крона, так и язвенного колита. Хотя четкой зависимости «доза–реакция» не установлено, глютен способен запускать врожденный и адаптивный иммунный ответ, ответственный за воспаление кишечника. Кроме этого, имеются сообщения, которые указывают на целиакию как на потенциальный фактор риска ВЗК. Представлены доказательства того, что микробиота и витамин D играют важную роль в стимуляции и регуляции иммунной системы. В свою очередь, дисбиоз кишечника может быть либо причиной локального воспаления кишечника, либо одним из потенциальных факторов, приводящих к хроническому воспалению, так же как и дефицит витамина D.

Infl ammatory bowel disease (IBD) includes ulcerative colitis (UC) and Crohn’s disease (CD), which are characterized by chronic infl ammation in the gastrointestinal tract. The diseases have a multifactorial etiology, including genetic predisposition, gut microbiota, environmental factors, diet, lifestyle, and socioeconomic status. There is a steady increase in IBD throughout the world, especially in Scandinavia, North America, and Canada, Israel. The contribution of diet to the development and treatment of IBD is enormous. In 2020, the European Society for Enteral and Parenteral Nutrition (ESPEN) published recommendations on dietary management for IBD and provided information on the impact of food on the risk of developing diseases. It has been shown that the use of dairy products may have a predominantly protective eff ect in the etiology of CD and UC, although a clear dose-response relationship has not been established; Gluten is capable of triggering innate and adaptive immune responses responsible for intestinal infl ammation. In addition, there are reports that point to celiac disease as a potential risk factor for IBD. Evidence is presented that the microbiota and vitamin D play an important role in stimulating and regulating the immune system. In turn, intestinal dysbiosis observed in patients with IBD may be either a cause of local intestinal infl ammation or potentially one of the factors leading to chronic infl ammation in IBD, as well as vitamin D deficiency.