bluuebunny/crossref_metadata_2025 huggingface dataset:
poder de las emociones en la publicidad y su conexión con los consumidores
Authors:   , Echenique Gallardo Eliana
Published: May 2024

En los últimos años, a partir de la COVID-19 muchas marcas comenzaron a emplear en sus comerciales contenido emocional, ya que se dieron cuenta de la gran influencia en el comportamiento del consumidor frente a las actitudes hacia la marca y la intención de compra hacia los productos de dicha marca. Las grandes empresas se enfocan más en la publicidad emocional, se preocupan por los sentimientos y emociones de su target y en las experiencias que tienen con sus marcas o que quisieran tener. Estas empresas priorizan que sus campañas no solo ofrezcan el producto sino también que generen un sentimiento por la marca y creen un ambiente conmovedor con sus clientes actuales, pero también en los potenciales. Este estudio se enfoca en identificar la percepción de estudiantes universitarios de último ciclo de la carrera de ingeniería sobre el uso de apelar a las emociones en la campaña “Este 2022, unidos nada nos podrá vencer” del BCP. Este estudio se posiciona en un paradigma y diseño fenomenológico. La técnica de muestreo teórico son a veinte estudiantes universitarios de último ciclo de la carrera de ingeniería entre los 19 a 25 años en donde se realizaron las entrevistas semiestructuradas mediante un análisis temático para delimitar por temas y categorías. El hallazgo, para los universitarios de último ciclo las emociones que genera la campaña, son alegría, orgullo, esperanza y nostalgia de seguir trabajando y luchando juntos para lograr todas sus metas.
Centro cultural de arte urbano en el distrito del Callao
Authors:   , Amayo Rubio Samantha
Published: May 2024

La presente tesis plantea un Centro cultural de arte urbano en el distrito del Callao que permita la interrelación espacial entre el edificio, su entorno y el artista y de esta manera fomentar las actividades culturales. Todo ello se logrará a través de los principios de mat building que hace referencia a esta necesidad espacial y una arquitectura capaz de diseñar sistemas abiertos que puedan modificarse o adaptarse en relación con el paisaje y el tejido urbano existente. Callo se presenta como el escenario idóneo ya que en los últimos años viene albergando distintas manifestaciones de arte urbano. Es por ello, que un centro cultural en este distrito permitirá brindar soporte de infraestructura y espacios necesarios para el aprendizaje y la práctica. Gracias al arte urbano, las personas y/o agrupaciones desarrollan sus dotes artísticos y afianzan la relación con la ciudad a través de performances en público como la danza (break dance), música (rap), teatro (circo), grafiti y muralismo. De esta manera, se identifica al arte urbano como un movimiento que involucra a los jóvenes y que al dotarles de una infraestructura adecuada pueden alcanzar un nivel de profesionalismo para convertirse en máximos representantes de nuestro país.
Influencia del estilo de liderazgo en la toma de decisiones en un contexto de trabajo remoto en las AFP del Perú, 2022
Authors:   , Araujo Esquivel Keisy , Huamantupa Velasco Cristian
Published: May 2024

La presente investigación es de alcance correlacional, es decir, tiene como objetivo conocer la influencia de la variable independiente estilos de liderazgo en la variable dependiente influencia en la toma de decisiones. El diseño no experimental es de corte transversal, ya que no se manipularon las variables de investigación y el recojo de información se dio en un solo momento. Para lograr el propósito de nuestra investigación hicimos uso del método cuantitativo a través de la herramienta encuesta tipo Likert a 315 trabajadores de las AFP del Perú. El análisis de fiabilidad obtenido de todas las preguntas en conjunto realizadas para el estudio nos arrojó un resultado de 0.832 demostrando la fiabilidad del estudio a partir de nuestras variables, ya que supera el 0.7. También, existe asociación entre las variables y la significancia, ya que aprueban las hipótesis alternas dando lugar a que los diferentes estilos liderazgo estudiados en la presente investigación influyen en la toma de decisiones, a excepción del Laissez Faire que tiene una naturaleza más autoritaria frente a los otros estilos.
Informal Economy Perspectives on the Prevalence of Worst Forms of Child Labour in Bangladesh’s Leather Industry
Authors: Maksud A.K.M , Hossain Khandaker Reaz , Sayed Sayma , Aked Jody
Published: May 2024

The CLARISSA programme aims to understand the dynamics that are central to running a business in the informal economy in Bangladesh’s leather industry and explore how and why worst forms of child labour become a feature of business operations. This research paper explores the findings from semi-structured interviews with business owners operating enterprises involved in leather processing and production across three prominent neighbourhoods and business districts in and around Dhaka. A focus on the leather industry in Bangladesh is an opportunity to explore the demand side of the child labour issue in a situated way, with the intention of bringing the lived experience of business owners to pre-existing literature on poverty entrepreneurship, supply chain governance, and political economy. The paper details the risks and stressors business owners face, the relationships they have with other informal and formal enterprises in the supply chain system, and their rationale for hiring children. Business owners experience poverty and financial precarity, taking significant financial risks to sustain enterprises that are barely viable economically. Stuck in vicious operating cycles, on ‘produce now, pay later’ credit arrangements, enterprises respond by squeezing labour budgets. The need for cheap labour is amplified by price points at lower than the cost of production. To understand why child labour has been so difficult to ‘end’, an informal economy business perspective points to the economic dysfunction of complex supply chains, particularly mediated by downward financial pressures produced and reproduced by highly fragmented manufacturing processes in cost-driven markets. When poverty and precarity among informal economy business owners intersects with formal economy power, the result is business models that rely on children as cheap labour. The findings make clear the policy value of engaging business owners in the informal economy in efforts to reduce worst forms of child labour, especially given the insights they can offer about how, when, and why supply chain systems are at risk of depending on children for the provision of goods and services.
Trade-off between Outreach and Profitability in Microfinance Institutions: Evidence from Bangladesh
Authors: Aminudin Ma'ruf  , Hamim Azad
Published: May 2024

Claims have been made that the purpose of microfinance is to alleviate poverty and remain sustainable. Hence, there is a trade-off between outreach to the low-income community and financial profitability. This research study tried to examine the trade-off between outreach and profitability of microfinance institutions in the context of Bangladesh. This study uses a data sample of 433 Microfinance Institutions obtained from the Microcredit Regulatory Authority on Microfinance Institutions in Bangladesh. Factors that significantly influence the outreach are the Total number of borrowers and Loan size to borrowers, while the profitability, is Equity to asset and Total assets. The result shows that there is significant evidence of a trade-off between outreach and profitability in Microfinance Institutions in Bangladesh. Furthermore, the paper recommends Microfinance Institutions remain small in order to maximize their outreach and urges policymakers to develop robust regulations on microfinance to help the poor community and support the nation’s economy for long-term prosperity.
Implikasi Komitmen Kepemimpinan Islam dan Dimensi Green Finance dalam Mendorong Kinerja Berkelanjutan Perbankan Syariah Indonesia
Authors: Alfarizi Muhammad , Kamila Hanum Rastinia , Andriana Firmansyah Almayda , Kurnia Sari Rini
Published: May 2024

Konsep Green Finance (GF) dipandang sebagai awal dari pengembangan ekonomi hijau lembaga keuangan di Indonesia. Perbankan syariah sebagai lembaga keuangan syariah memiliki potensi tinggi untuk berkontribusi dalam ekosistem GF yang berkelanjutan. Komitmen bank syariah dan peran kepemimpinan syariah dalam manajemen puncak diperlukan dalam implementasi GF pada program kehijauan internal-eksternal. Penelitian ini bertujuan untuk eksplorasi pengetahuan lebih lanjut mengenai faktor pengaruh green financing terhadap kinerja berkelanjutan bank syariah di Indonesia dengan mempertimbangkan komitmen bank dan kepemimpinan syariah. Studi ini mempertimbangkan pendapat bankir melalui studi kuantitatif survei online menggunakan analisis SEM PLS dalam menguji sembilan hipotesis. Hasil penelitian menunjukkan bahwa Kepemimpinan Islam berpengaruh signifikan terhadap dimensi ekonomi, sosial dan lingkungan GF sedangkan komitmen bank berpengaruh tidak signifikan terhadap dimensi sosial. Selanjutnya, pengujian hipotesis dimensi GF terhadap kinerja bank syariah yang berkelanjutan menunjukkan pengaruh yang signifikan terhadap dimensi ekonomi-lingkungan dan tidak signifikan terhadap dimensi sosial. Studi ini menyoroti pentingnya komitmen perbankan syariah dan kepemimpinan ekologis Muslim pada manajerial bank syariah untuk mendorong GF dalam ekspansi ekonomi jangka panjang yang berkelanjutan, memajukan sektor perbankan serta mendorong ekonomi hijau berkelanjutan yang dicanangkan pemerintah Republik Indonesia. Oleh karena itu, implikasi kebijakan manajerial utama dibahas.
Pinpointing the Determinants of Financial Literacy: Empirical Evidence of Indonesian Employees in Malaysia
Authors: Rizal Achmad , Susilo Adib , Rahman Abadi M. Kurnia , Lahuri Setiawan , Abdullah Nurdianawati Irwani , Che Embi Nor Azizan
Published: May 2024

This paper investigates the determinants variables of financial literacy through Exploratory Factor Analysis among Indonesian employees’ works in Malaysia. This study is quantitative study with 117 respondents. The data from respondents are collected through questionnaire on five-point Likert scale. Data analysis employs EFA (Exploratory Factor Analysis) which reduce the factors into expected variables. The study found that there 7 factors emerged in based on data analysis namely, financial literacy contributes with higher percentages factors 13.93%, financial planning contributes with 11.28%, financial control with 9.86%, exchange rate awareness with 9.52%, financial attitude with 9.07, financial subjective norms with 8.76, and lastly financial awareness contributes 6.93%. Meanwhile, simultaneously all variables have commutative percentages about 69.38%. Further studies are required to investigate or examine each emerged variables for example, SEM, Regression analysis, One Way ANOVA, and so on. Moreover, wider coverage of research sample and research object also suggested.
A CONCEPTUAL MODEL FOR DESIGNING TEACHERS’ SELF-DIRECTED AND WELL-BEING-CENTERED PROFESSIONAL DEVELOPMENT
Authors:   Department of Theory and Practice in Teacher Education, University of Tennessee, Knoxville, Tennessee, Starks Francheska
Published: May 2024

Research shows that educators often experience significant levels of stress in the workplace that impact their enthusiasm about the profession and longevity in the education field. Some personal impacts of stress on educators may include emotional numbing, feeling shut down, loss of energy, and increased illness or fatigue. Recently, some schools and districts have begun investing in programming to support educator well-being; however, these initiatives are rarely developed and co-led by educators themselves. The purpose of this paper is to introduce a research-based for designing and implementing educator-directed programming that seeks to support the well-being of K-12 educators. Implications for future research and practice are provided at the end of the paper.
Prevention and treatment of type 1 diabetes: in search of the ideal combination therapy targeting multiple immunometabolic pathways
Authors: Pinheiro Marcelo Maia , Pinheiro Felipe Moura Maia , Garo Maria Luisa , Pastore Donatella , Pacifici Francesca , Ricordi Camillo , Della-Morte David , Infante Marco
Published: May 2024

Type 1 diabetes (T1D) represents an autoimmune disease caused by the gradual immune-mediated destruction of the insulin-producing beta cells within the pancreatic islets of Langerhans, resulting in the lifelong need for exogenous insulin therapy. According to recent estimates, T1D currently affects about 8.4 million individuals worldwide. Since a definitive biological cure for this disease is not available yet, there is a great need for novel therapeutic strategies aimed at safely and effectively altering the natural history of the disease during its sequential stages. Ideal therapeutic goals in T1D include the prevention of autoimmune beta-cell destruction, the preservation of residual beta-cell mass and endogenous insulin secretion, the replacement and/or regeneration of beta cells, as well as automated insulin delivery through advanced closed-loop artificial pancreas systems. With this regard, an important research area focused on the identification of a definitive biological cure for T1D is represented by the investigation of immunotherapeutic and beta-cell-protective agents used as disease-modifying therapies to forestall or eliminate insulin dependence. In this commentary, we discuss the reasons why the use of combination therapies targeting the multiple immunometabolic dysfunctions associated with T1D (other than beta-cell autoimmunity) is likely to be more effective in preserving beta cell function in individuals at different stages of T1D, as compared to the use of single therapeutic agents.
ANALYSIS OF THE LEVELS OF NON-OPTIMALITY MODES OF LOW-VOLTAGE ELECTRICAL NETWORKS WITH UNEVENNESS OF ELECTRICITY GENERATION AND CONSUMPTION
Authors: Hilevych Kateryna
Published: May 2024

An analysis of the levels of non-optimality of electricity generation and consumption processes in low-voltage electrical networks with the unevenness of electricity generation and consumption was carried out. Measures to reduce electricity losses in such networks have been systematized. The assessment of the influence of uneven electricity generation and consumption on the level of costs in the electric network is given. To reduce electricity losses by analyzing the potential of managing power supply modes, it is proposed to use the method of assessing non-optimal levels of the local electric power system using the reactive power of Frize QF.
The non-optimality of selection from the generator and consumption of electricity loads is evaluated from the point of view of the operation of the electricity system as a whole. The degree of deviation from uniform energy consumption with the average level of active power transfer for a given time interval was chosen as an evaluation criterion. The power of Frize QF is used to compare the real mode of operation of the electric power system with the optimal mode. This calculation can cover any time. The use of QF made it possible to unify the analysis of energy supply processes of electric power system loads, providing the possibility of retrospective, current, and prospective analysis. The use of Frize QF power provides an opportunity to assess technical, economic, and technological factors, such as the influence of various factors on the appearance of additional electricity losses, and the stability and stability of the system when changing the operating modes of generators and loads.
The conducted analysis made it possible to propose an algorithm for assessing the level of optimality of mode management in electrical networks, which can be implemented both with the involvement of a dispatcher and in automatic mode. The evaluation of the addressable impact based on the Frize power is of particular relevance for local electric power systems, where various types of generators of limited power based on renewable energy and various types of energy consumption technologies are widely used.
Perkembangan Pelaksanaan Urusan Pemerintahan Umum di Daerah: Studi terhadap Pelaksanaan Urusan Pembinaan Pancasila dan Wawasan Kebangsaan
Authors: Gani Wardhana Allan Fatchan , Hakiki Yuniar Riza , Nurcahyani Rahman Diva Febrina
Published: May 2024

General government affairs fall under the authority of the President as the head of Government, which in fact are carried out by Heads of the Region, one of which is the sub-affairs of developing the value Pancasila and the nationalism insight. This authority is in fact exercised by the Regional Government by establishing Regional Regulations (Perda). In fact, regional regulations are enacted in order to carry out government affairs which fall under regional authority, carry out regional autonomy and assistance tasks, and accommodate special regional conditions. This research examines two features, first, can the authority for general government affairs be divided between provinces and districts/cities? Second, how is the development of the implementation of authority for general government affairs in the regions? The research method used is normative juridical with a statutory and a conceptual approach. The results of this research are first, that although general government affairs are the authority of the President, their implementation is divided among the regions. The matter of fostering Pancasila and nationalism insight reaches all regions in Indonesia and is certainly not effective if it is only carried out by the President. Second, general government affairs which were originally carried out on the principle of deconcentration have developed towards decentralization. Strengthening the independence of Regional Governments in carrying out general government affairs is reason enough. Such as the formation of the Regional Regulation on Pancasila Education and National Insight which accommodates locality aspects and financing from the APBD. Regions in the implementation of general government affairs are ultimately not only administrative regions, but have become autonomous regions.
Penegakan Hukum Pungutan Liar di Jawa Barat dalam Pelayanan Publik Pasca Covid-19
Authors: Mahmud Ade
Published: May 2024

This research analyzes the urgency of developing electronic-based public services in preventing criminal acts of illegal levies (extortion) to support transparent and good quality government governance and offers ideas for law enforcement to eradicate extortion, which is remains considerably lacking in West Java Province, especially after Covid-19. Hence the problem formulation focuses on the issue of how to develop public services to prevent the practice of extortion and how to build law enforcement to eradicate extortion in West Java Province. This paper is normative legal research using statutory approach and conceptual approaches that uses secondary data in the form of books, law journals, research reports, magazines, statutory regulations, and recapitulation of agency performance data to produce accurate and accountable conclusions. The results of the research conclude that the development of electronic-based services can be realized by changing manual services to digital ones, upgrading digital services with new features that accommodate people's needs, increasing e-money payments that are connected to the banking system followed by developing the Public Service Mall (MPP) concept that is accessible to the public. Law enforcement overcomes extortion by building reporting system connectivity that is directly connected between SiBerli and the extortion reporting system in agencies/institutions/units providing public services, implementing a reward and punishment system objectively as well as applying administrative sanctions for officials who abuse their authority and criminal sanctions as the ultimum remedium if other legal instruments are unable to resolve the crisis.
Influence of bleaching gels containing 45S5 Bioglass on enamel color, surface roughness, and microhardness
Authors: Dascanio Rafael , Silva Coelho Camila Siqueira , Souza Marina Trevelin , Zanotto Edgar Dutra , Cavalli Vanessa
Published: May 2024

This study evaluated the effects of 45S5 Bioglass (BG) in combination with 35% hydrogen peroxide (HP) on enamel color, surface roughness, and microhardness. Enamel blocks (n = 10) were treated with PC: 35% HP gel—positive control; HP_BG: HP combined with BG (0, 2.5, 5, 7.5, and 10 wt%); and NC: without treatment—negative control. Bleaching was carried out in three 40-min sessions, 7 days apart. Specimens were stored in artificial saliva for 14 days after bleaching. Color parameters (ΔL, Δa, Δb), color change (ΔE00), whiteness index (ΔWID), surface roughness average (ΔRa), and microhardness were measured at baseline (T0), 24 h (T1), and 14 days after bleaching treatment (T2). The %SHL (surface hardness loss) was calculated at T1 and T2. Data were analyzed by ANOVA and Tukey tests (α = 0.05). HP_BG and PC exhibited no differences, and these groups displayed higher ΔE00, Δb, and ΔWID than NC, regardless of the BG concentration or time points (p < 0.05). No differences were noted in ΔRa, ΔL, and Δa among groups (p > 0.05). At T2, 10%BG displayed a lower %SHL than 0%BG and PC, and all BG-containing groups showed a lower %SHL than PC (p < 0.05). The addition of BG did not influence the whitening efficacy of HP and did not change enamel roughness. Moreover, the combination of BG and HP was found to be effective in controlling enamel surface microhardness.
Multicriteria assessment of transport network security
Authors: Ekhlakov Roman Sergeevich , Sivakova Tatiana Vladimirovna , Sudakov Vladimir Anatolievich
Published: May 2024

Road safety is one of the most important factors in the efficiency of a transport network. The purpose of the study is methods for analyzing criteria affecting traffic safety in the transport network. The weight of the criteria was calculated using the paired comparison method. The ranking of alternative routes was carried out using the order of preference technique based on similarity to the ideal solution. The results of the study can be used when choosing a rational route, taking into account not only the speed of movement, but also various risks.
IOT Soft Starter Revolutionizes Single-Phase Induction Motor Control
Authors: Hadiyatulloh Moh , Wisaksono Arief
Published: May 2024

Induction motors often face issues with large initial currents that can disrupt networks and damage the motors. This study designs a soft starter for single-phase induction motors using an IoT-based Arduino Uno system to regulate initial current surges and enable remote monitoring via the Blynk App. The system uses the AC Light Dimmer module controlled by Arduino Uno and Wemos D1 Mini microcontrollers, with the PZEM-004T sensor detecting current and voltage. Experimental results showed a significant reduction in initial current, averaging 0.48 A and 201.90 V within 10 seconds. Additionally, the system allows for monitoring from up to 16 km away using an Android smartphone, providing an effective solution for managing induction motor performance and ensuring reliable operation.
Highlight:

Renewable technology for controlling single-phase induction motor initial current.
Software and system flowcharts illustrate IoT-based motor control.
Significant reduction in initial current demonstrated in induction motor testing.

Keywoard: Induction Motors, Soft Starter, IOT, Arduino Uno, Remote Monitoring.
The Role of Single Fathers in the Moral Development of Children Aged 5-6 Years
Authors: Yuliana Yanda , Busyro Karim Muhammad
Published: May 2024

This study aims to explore the role of single fathers in the moral development of children aged 5-6 years in Nguwok Village, where morality is considered a crucial aspect of human development and life. The research method employed is qualitative with a descriptive approach. The subjects of this study are two single fathers with children aged 5-6 years residing in Nguwok Village, Modo District, Lamongan Regency. Data collection techniques include interviews, observations, and documentation, with data analysis following the Milles and Huberman model. The findings from this research indicate that single fathers play a significant role in nurturing their children, including bathing, feeding, and assisting with homework. The second role involves providing education, particularly in moral values, the third is acting as a mentor, which includes accompanying and disciplining the children, and the last role is that of a friend, ensuring the child feels comfortable talking or sharing stories with their father. According to the research results, the moral development of children raised by single fathers shows a balanced development between capability and incapability. The aspects of moral development examined include speaking politely, practicing religious worship, expressing gratitude when receiving something, maintaining personal and environmental cleanliness, and apologizing when making mistakes.
Development and Characterization of MoO3 / NiFe2O4 Nanocomposite Photocatalyst for Organic Pollutants Removal towards Sustainable Water Remediation
Authors: Ganesh Anju , Simon Sanu Mathew , John Nayomi , Rajan Richu , Thankachan Smitha
Published: May 2024

Photocatalysis is emerging as one of the most important methods for wastewater treatment. Azo dyes are a prominent class of water pollutants that disrupt the balance of the water ecosystem due to its toxicity. Various met.al oxides and their composites are effective in dye degradation due to their band gap range and porosity. Herein, the efficiency of MoO3/NiFe2O4 nanocomposite as a photocatalyst on the degradation of congo red dye for water remediation is studied. MoO3/NiFe2O4 nanocomposite was fabricated by ultrasonication using nickel ferrite nanoparticles prepared from sol-gel autocombustion method and α-MoO3 nanorods were prepared by hydrothermal method. The phase identification of samples was carried out using X- Ray Diffraction (XRD). The spinel structure of NiFe2O4 was confirmed using Fourier Transform Infrared Spectroscopy (FTIR). Transmission Electron Microscopy (TEM) image of ferrite exhibits the formation of nearly spherical particles and Selected Area Electron Diffractometry (SAED) pattern indicates polycrystalline nature. Scanning Electron Microscopy (SEM) images of MoO3 confirm its nanorod morphology. The Field Emission Scanning Electron Microscopy (FESEM) image of nanocomposites disclose attachment of spherical nanoferrite in MoO3 nanorods. The elemental composition of the composite is determined by Energy Dispersive X-ray Analysis (EDAX) and X-Ray Photoelectron Spectra (XPS) analysis. The photocatalytic activity of samples on Congo Red was studied using UV-Visible spectrophotometry and the effect of composition of nanocomposite were studied. MoO3 / NiFe2O4 nanocomposite is found to exhibit maximum efficiency of 74.47% in 30 minutes whereas NiFe2O4 removes only 49.40% and MoO3 52.04%. The scavenger study indicates that the reactive species involved in the reaction mechanism is .OH free radical.The antibacterial activity of the samples on Escherichia coli and Staphylococcus aureus was studied by the well diffusion method.
Effects of Lacticaseibacillus paracasei 207-27 on intestinal function and its regulatory mechanism in patients with chronic constipation
Authors: An Yanjun , Jia Yong , zhang Xiaoling , Li Xiaoqiong , Zhu Liying , Wang Xin , Ze Xiaolei , Li Jinjun
Published: May 2024

Background & Aims: Constipation is a disorder affecting the quality of life of patients, and symptoms following current treatments still need to be improved. Although probiotics treat constipation, the efficacy and safety of this therapy remain controversial. This a randomized, double-blind, placebo-dense controlled trialaimed to investigate the clinical impact of the probiotic bacterium Lacticaseibacillus paracasei 207-27 on chronic constipation.
Methods: We recruited 80 patients aged 18–65 with chronic constipation and divided them into probiotic (Lacticaseibacillus paracasei 207-27) and placebo (maltodextrin) groups. The participants were treated twice daily for 4 weeks, and stool samples and questionnaires were collected before and after treatment. The 16S rRNA sequencing and untargeted metabolomics data were analyzed.
Results: Bowel movements, total short-chain fatty acid, and propionic acid were significantly improved in the probiotic group compared with in the placebo (control) group (p<0.05) following the 4-week intervention. After the intervention, the placebo group had higher Phylum Firmicutes number (p<0.0001) and abundance of Escherichia-Shigella genus (p=0.0257) and Roseburia genus (p=0.0202) but lower abundances of Actinobacteria phylum (p=0.0177), Bifidobacterium genus (p<0.0001), and Roseburia genus (p=0.0001) than the probiotic group. Probiotic intervention reduced the abundance of the Bacteroides genus (p=0.0001) and Blautia genus (p=0.0213) compared with that before intervention (week 0). The analysis of non-target metabolites revealed a significant increase in 3-sulfinoalanine associated with taurine and hypotaurine metabolism in 3-methylxanthine associated with caffeine metabolism and a significant downregulation of 3-methylindolepyruvate associated with tryptophan metabolism after probiotic intervention.
Conclusion: Lacticaseibacillusparacasei 207-27 improved constipation symptoms and altered the intestinal microbiota, which could improve patients’ quality of life.
Trial registration: chictr.org.cn ChiCTR2200056274, 03/02/2022.
Simple workflow for high-titer microbial production of small antibodies
Authors: Ishii Jun , Tominaga Masahiro , Nakamura Yasuyuki , Sasaki Daisuke , Ogura Kazumasa , Suematsu Kohei , Ito Yoichiro , Kondo Akihiko
Published: May 2024

Increasing demand for biologics necessitates the rapid production of antibodies and their mimetics. Herein, we established a rapid workflow to develop a fermentation process for high-titer production of small antibodies using the yeast Komagataella phaffii. We screened yeast strains with the optimal gene copy number of target proteins and applied them to a feedback-controlled, high-cell density fed-batch fermentation, and achieved high-titer production of small antibodies with titers 3–7 g/L.
Title：Prevalence and risk factors of overweight and obesity among children and adolescents in Hangzhou: a cross sectional study
Authors: Zhao Lijuan , Jiang Xiujun , Zhang Wenhui , Hao Li , Zhang Yuting , Wu Shangxi , Xu Hong , Zhu Bing
Published: May 2024

Purpose: To investigate the prevalence and influencing factors of overweight and obesity among primary and secondary school students in Hangzhou city, and provide ideas for the formulation of overweight and obesity prevention and control measures.
Methods: A total of 353,783 primary and middle school students in 13 districts of Hangzhou city were investigated with physical examination. Using a stratified cluster random sampling method, 6,148 students of primary and junior high school from 24 schools were investigated via questionnaires. Univariate and multivariate logistic regression were used to screen possible risk factors of overweight and obesity.
Results: The overall overweight and obesity rate was 27.20%, with the increase of the school period, the prevalence of overweight and obesity among students showing downtrend (χ2=14.47, P＜0.01). The prevalence of overweight and obesity in girls is lower than that in boys (χ2=69.79, P＜0.01); the prevalence of overweight and obesity in urban students is higher than that in suburban students (χ2=2.01, P=0.02). High blood pressure, had menstruation or nocturnal emission, eating fresh fruit ≥1 time a day, daily brushing ≥2 times and bullying victimization are independently associated with higher prevalence of overweight and obesity. Moreover, the increased school period, girls and boarding student are protective factors for overweight and obesity.
Conclusions: The overweight and obesity prevalence among children and adolescents in Hangzhou is still at a relatively high level, and is affected by most factors such as high blood pressure, had menstruation or nocturnal emission, eating fresh fruit frequency, school period and gender, needing targeted intervention measures.
Validation of the Arabic version of the reduced Horne-Östberg Morningness- Eveningness Questionnaire (rMEQ)
Authors: CHAAYA Roni , CATTAN Rebecca , LAHOUD Christele , MERHI Georges , KAHWAJI Georges-Junior , LAHOUD Rachele , MATTAR Hanna , OBEID Sahar , HALLIT Souheil , FEKIH-ROMDHANE Feten
Published: May 2024

Introduction: Individual differences in sleep-wake cycles give rise to 'morningness-eveningness' or 'chronotypes'. Chronotype preferences are governed by internal circadian rhythms and influenced by external cues. The assessment of chronotypes is essential for understanding these preferences, and the Reduced Morningness-Eveningness Questionnaire (rMEQ) has been developed for this purpose. The purpose of this study was to examine the Arabic rMEQ's psychometric properties in terms of validity, reliability and measurement invariance in young adults.
Methods: Three hundred thirty Arabic-speaking participants from the general population of Lebanon, comprising 67.3% females with a mean age of 21.75 ± 2.43 years (range: 18-33), were recruited for this study. The participants were asked to fill out an online questionnaire consisting of the Arabic versions of the rMEQ, Pittsburgh Sleep Quality Index (PSQI), and the Lebanese Anxiety Scale (LAS).
Results: Confirmatory factor analysis (CFA) indicated a modest fit for the one-factor model of the rMEQ. Internal reliability was good, with ω = .75 and α = .70. Additionally, cross-sex invariance analysis showed support for configural, metric, and scalar invariance, with no significant differences in rMEQ scores between males and females. Concurrent validity revealed significant moderate correlations between higher rMEQ scores and lower depression, better sleep quality, and lower anxiety.
Conclusion: The Arabic version of the rMEQ demonstrated adequate psychometric properties in a Lebanese young adult population. The CFA results support a one-factor model, suggesting that the Arabic rMEQ measures the same underlying construct as the original version. Overall, the Arabic rMEQ appears to be a valid and reliable tool for evaluating morningness-eveningness in Arabic-speaking young adults, with potential applications in cross-cultural chronotype studies.
Two quantitative multiplex assays for the detection of P. falciparum asexual rings and male/female gametocyte developmental stages from human tissues
Authors: Abagna Hamza B. , Tackie Richmond G. , Ansah Felix , Kyei Joseph , Tackie Emmanuel O. , Akoliga Samuel , Beshir Khalid , Tagboto Senyo , Korpisah Joseph K. , Wezena Cletus A. , Deitsch Kirk W. , Alano Pietro , Awandare Gordon A. , Binka Fred N. , Sutherland Colin J. , Urban Britta C. , Dinko Bismarck
Published: May 2024

Background
Malaria, caused by Plasmodium parasites, remains a significant global health challenge. Gametocytes are the sexual forms of the parasites which do not cause disease but are responsible for parasite transmission to the mosquito vector, often even after successful treatment of infected individuals. The density and sex ratio of gametocytes play a major role in determining malaria transmission dynamics. Sensitive methods for detecting and quantifying gametocyte developmental stages and sex ratios are critical tools for achieving Plasmodium transmission reduction in the malaria elimination agenda.
Methods
Two sensitive triplex real-time PCR gametocyte sex-specific (Assay I) and gametocyte developmental stage-specific (Assay II) assays were developed. Assay I was designed for the detection and quantification of male and female gametocytes and of asexual rings, based on the amplification of male (PF3D7 1311100, Pf13), female (PF3D7 0903800, CCp4) gametocyte- and asexual ring- (PF3D7_0501300, SBP1) transcripts. Assay II was designed for the detection and quantification of transcripts marking early (PF3D7_1477700, PHISTa), intermediate (PF3D7_1346700, Pfs48/45) and late (PF3D7_1031000, Pfs25) stage gametocytes. Assays were tested and validated using 10 matched treatment day 0 and 7 venous blood samples from a study evaluating gametocyte immune responses in children (GI study) and 10 matched peripheral blood samples and bone marrow aspirates obtained from a study investigating gametocyte development in semi-immune Ghanaian individuals (BM study).
Results
Assay I detected transcripts of ring stages (SBP1), male (Pf13) and female (CCp4) gametocytes in 40%, 20% and 70% of the samples in the GI study and in 60%, 30% and 70%, respectively, in samples of the BM study. Assay II detected transcripts of early (PHISTa), intermediate (Pfs48/45) and late stage (Pfs25) gametocytes in 40%, 50% and 40% of the samples from peripheral blood compared to 70%, 20% and 40%, respectively, from bone marrow aspirates of the BM study.
Conclusions
The one-step multiplex assays described here can be readily used to measure densities of male and female gametocytes for sex ratio determinations and to quantify proportions of gametocyte developmental stages in peripheral blood samples and in bone marrow aspirates of malaria-infected individuals.
Partner Conflict among a Cohort of Women during the Index Pregnancy as measured in the Extended Postpartum Six Weeks Period and its correlates in Ethiopia: Community Based Longitudinal Data; A Multilevel Analysis
Authors: Damtew Solomon Abrha , Atinafu Niguse Tadele , Gidey Mahari Yidego , Awoke Tesfamichael
Published: May 2024

Introduction: Current intimate partner violence (IPV) in Ethiopia is considerably high. This study aimed at determining the prevalence of the IPV during the index pregnancy as measured in six weeks postpartum among women in the extended six postpartum period and identify its correlates. Documenting the magnitude of six week postpartum IPV during the index pregnancy as measured six weeks in the postpartum period and identifying factors affecting it contributes its share for the ministry and other relevant partners in tracking progress towards eliminating all forms of violence against women and girls by 2030. Methods: This study used PMA merged cohort 1 baseline and six week postpartum data which enrolled and collected data from currently pregnant women. Frequency was computed to describe the study participant’s characteristics, and chi-square statistics was used to assess cell sample size adequacy. Multilevel binary logistics regression was employed to identify correlates of IPV at the extended six postpartum period. Results were presented in the form percentages and odds ratio with 95% Confidence Intervals. Candidate variables were selected using p-value of 0.25. Statistical significance was declared at p-value of 0.05. Results: The proportion of IPV during the index pregnancy as measured six weeks postpartum women where who reported experiencing at least one for of physical or sexual IPV 6 weeks postpartum was 12.14% (10.66%, 13.79%). Over the same period a slightly higher percentage of women reported that they have experienced at least of form of sexual IPV 8.09% (6.91%, 9.44%) than experiencing at least one form of physical IPV 6.02% (4.94%, 7.31%). After controlling confounders, the likelihood of experiencing at least one form of physical and/or sexual IPV was 2.14 (1.04, 4.38) time higher among women whose husband had other wife’s compared to those who do not have. On the contrary, women who were residents of Afar region had 86% 0.14 (0.03, 0.79) lower odds of experiencing one form of physical and/or sexual IPV six weeks postpartum. Activities and efforts which are specific to regions and that address the problem of polygamy are hoped to address the problem IPV. Such activities can be delivered should be tailored along the maternal and new born care continuum.
Experiences with emergency distance education: A dilemma between face-to-face education and distance education in tour guiding
Authors: Altınay Özdemir Meltem , Tombaş Zeynep
Published: May 2024

Universities switched from face-to-face to emergency distance education as a solution to the crisis during the Covid-19 pandemic. This enabled face-to-face students to experience distance education. This study examined these experiences for tour guiding education. Distance education was available in tour guiding departments at a few Türkiye universities before the pandemic, and this was a discussion topic in academic. However, emergency distance education presented a dilemma for students: distance education or face-to-face education. Thus, the research includes students in the face-to-face tour guiding departments. A qualitative, phenomenological approach was employed to collect data using semi-structured interviews and an online questionnaire. Data were analyzed using thematic content analysis. The findings revealed that students preferred face-to-face education while being uncertain about the pros and cons of distance education. However, this decision should be underlined as not definitive. The study emphasizes that distance education is ineffective for tour guiding education due to the absence of practical courses, which are crucial for tour guiding, as well as effective communication. The study provides theoretical insights into the educational strategies used in tourism during crises and offers practical implications for enhancing distance education in higher education institutions.
Effect of GA3 as a priming agent on the growth of shallot (Allium ascaloncium L.) seedling
Authors: Rahmawati  , Syam’un Elkawakib , Riadi Muh , Ulfa Fachirah , Anshori Muhammad Fuad
Published: May 2024

This study aimed to evaluate and analyze the effect of priming using GA3 on the growth of various shallot varieties from seeds. This pot study was conducted at Exfarm, Faculty of Agriculture, Hasanuddin University from July to September 2022. The research was arranged in factorial with a randomized complete block design (RCBD) with two treatment factors. The first factor was seed priming consisting of control or no priming (S0), priming with water (S1), 25 mg L-1 GA3 (S2), 50 mg L-1 GA3 (S3) and 75 mg L-1 GA3 (S4). The second factor is the variety consisting of Tuk-Tuk (v1), Sanren F1 (v2), Lokananta (v3), and Maserati (v4). Seed performance testing is carried out by planting prime seeds in pots. Meanwhile, parameters observed included six agronomic parameters and three chlorophyll parameters. The results show that priming with GA3 at concentration of 75 mg L-1 significantly influence the plant height, number of leaves, fresh weight, chlorophyll b content, and total chlorophyll. Variety treatments recorded different responses to various parameters. The Lokananta variety recorded the highest average plant height and dry seedling weight. The Maserati variety recorded the largest average diameter of pseudo stems. Meanwhile, the interaction between GA3 at 75 mg L-1 and the Maserati variety has a significant effect on the root length of shallot seedlings. Then, the interaction between Tuk-Tuk varieties and GA3 75 mg L-1 priming gave the best effect on chlorophyll content.
Comparative impact of Arbuscular Mycorrhizal fungi from Moroccan soils and commercial inoculum on potato yield and nutrient composition
Authors: CHAFAI Wissame , Bouchentouf Halima , KHALID Ahmed
Published: May 2024

Potato (Solanum tuberosum L.) is a widely grown crop in Morocco. Mycorrhiza fertilization of potatoes needs to be monitored in order to observe their effects on the growth of potatoes. The aim of this study was therefore to test the effect of fungal strains on potato yield and tuber quality. The inoculation treatments included a commercial inoculum (T2), a natural inoculum (T3), represented by leek roots fragments, obtained after trapping by this host plant of AMF spores naturally present in the soil of the region of Guercif-Morocco, and a control treatment consisting of a sterile substrate. Our results showed significant differences in the frequency and intensity of mycorrhization between the T3 inoculum and the T2 inoculum, while control plants showed no AMF infection. Compared to the T1 control (non-inoculated plants), the gains in number of tubers/plant was 24% and 39% higher, whereas gains in yield was 34% and 48% higher for potato plants inoculated with T2 and T3 inocula, respectively. Furthermore, chemical analyses showed the important role of controlled mycorrhization in the accumulation of mineral elements; N, P, K, Zn, Cu and Fe in potato tubers. The T3 inoculum obtained from the soil of Guercif-Morocco allowed to obtain the best value of dry matter (16.82 g/100 g fM) and the best contents in Zn; K and P and the tubers.
EL PAPEL DE LA ANALÍTICA PREDICTIVA EN LA ANTICIPACIÓN DE CAMBIOS EN EL ENTORNO EMPRESARIAL
Authors: Calle García Aldrin Jefferson , Aviles Barcia Emely Michelle , Baque Reina Evelyn Andreina , Muñiz Rodríguez Frixon Steven
Published: May 2024

Este estudio se basó en el rol fundamental que desempeña la analítica predictiva en la anticipación de cambios en el entorno empresarial, examinando ejemplos de empresas líderes y sus resultados cuantitativos. La metodología conllevó la recopilación de datos secundarios de fuentes confiables y el análisis detallado de casos de estudio de empresas destacadas. A través de este enfoque, se identificaron tendencias y desafíos en el uso de la analítica predictiva en el entorno empresarial actual. Los resultados revelaron que la analítica predictiva tiene un impacto significativo en diversas áreas de las operaciones empresariales. Amazon, logró un aumento del 29% en sus ingresos mediante la implementación de algoritmos de recomendación basados en la analítica predictiva, resaltan el potencial de esta tecnología para impulsar los resultados financieros de una empresa. Además, casos como el de Procter & Gamble, que redujo sus costos de inventario en un 25% utilizando modelos predictivos para pronosticar la demanda de productos con mayor precisión, destacan la capacidad de la analítica predictiva para generar eficiencias operativas significativas.
EL PAPEL DE LA ANALÍTICA WEB EN LA OPTIMIZACIÓN DE LA GESTIÓN ORGANIZACIONAL
Authors: Bellettini Vela Gabriel , Toala León Damara Yadira , Baque Arteaga Mayerli Xiomara , Barreto Bravo Angie Pierina
Published: May 2024

La analítica web es un papel fundamental en la optimización de la gestión organizacional, es así que este estudio analiza su impacto en empresas líderes como Amazon, Netflix, Walmart y Tesla. El objetivo fue comprender cómo la analítica web influye en la toma de decisiones, la experiencia del cliente, la eficiencia operativa y la ventaja competitiva. Se realizó una revisión exhaustiva de la literatura y se recopilaron datos empíricos sobre el uso de la analítica web. Los resultados revelaron que la analítica web es fundamental para mejorar la capacidad de tomar decisiones estratégicas, aumentar la retención de clientes y reducir costos operativos. Amazon ha experimentado un aumento del 29% en los ingresos netos, mientras que Netflix ha visto un incremento del 32% en la retención de clientes. Walmart ha reducido los costos de inventario en un 7% y mejorado la precisión de las previsiones de demanda en un 15%, y Tesla ha reducido los costos de producción en un 10% y mejorado la eficiencia de la producción en un 15%.