bluuebunny/crossref_metadata_2025 huggingface dataset:
Recuperação de áreas degradadas por voçorocas: identificação das técnicas utilizadas no ano de 2023, a partir do Google Acadêmico
Authors: Amorim Thaumaturgo da Silva Gabriel , Teixeira Guerra Antônio José
Published: September 2024

Com o aumento dos eventos extremos de chuva relacionados às mudanças climáticas, a erosão dos solos tornou-se uma crescente preocupação entre os pesquisadores, que buscam compreender e mitigar os impactos por meio de técnicas de monitoramento, controle e recuperação. Portanto, este estudo visa identificar as técnicas de recuperação de áreas degradadas por voçorocas, aplicadas em estudos de caso realizados no Brasil, com recorte temporal para o ano de 2023, disponibilizados pela plataforma do Google Acadêmico. A pesquisa torna-se relevante pela necessidade de compreender as técnicas que estão sendo utilizadas, bem como a sua eficácia e eficiência, frente aos impactos das mudanças climáticas e os eventos extremos de precipitação. Por fim, este trabalho busca fornecer subsídios para futuras pesquisas na temática de recuperação de áreas degradadas, contribuindo para uma gestão sustentável dos solos.
A unidade de paisagem floresta amapaense: e a incidência de desmatamento de corte raso entre os anos de 2001 e 2020
Authors: Costa da Silva Tatiane , Rauber Alexandre Luiz
Published: September 2024

O artigo propõe fazer uma análise da evolução do padrão espacial e temporal das transformações da paisagem provocadas pelo Desmatamento de Corte Raso nos mais de 10,7 milhões de hectares que compõem a Unidade de Paisagem Floresta Amapaense. O objetivo geral consiste em analisar o padrão espacial e temporal das transformações da paisagem por Desmatamento de Corte Raso na Unidade de Floresta do Estado do Amapá entre os anos de 2001 e 2020. Os específicos foram: a) Mapear as áreas transformadas por Desmatamento de Corte entre os anos de 2001 e 2020; b) Analisar o padrão espacial e temporal do Desmatamento de Corte Raso entre os anos de 2001 e 2020. A categoria geográfica utilizada para desenvolver a pesquisa foi a paisagem pois é a partir dela que é possível observar a evolução multitemporal. Foi utilizado os dados de Desmatamento de Corte Raso obtidos na plataforma PRODES/INPE e também do banco de dados MapBiomas onde possui um módulo sobre Desmatamento. Os dados foram organizados e sobrepostos ao limite estadual e da Unidade de Paisagem Floresta utilizando como ferramenta o software TerraView. É possível constatar que a taxa de Desmatamento de Corte Raso na Unidade de Paisagem Floresta Amapaense entre os anos de 2001 e 2020 foi de 0,89% representando em torno de 100 mil hectares e uma média anual de 5 mil hectares/anuais.
Strategic implementation of outcome-based education
Authors: Tjandra Ellysa , Ferdiana Ridi , Kusumawardani Sri Suning
Published: September 2024

The paradigm of higher education in Indonesia is currently changing to Outcome-Based Education,  which focuses on the curriculum's accomplishment of student outcomes. Measurement of the degree of learning accomplishment in a course requires the use of a learning outcome attainment method, and providing student skills achievement reports in programming courses is crucial to improving student success in computer science study programs. This study proposes a standardized learning outcome measurement technique to provide a comprehensive course learning outcome attainment with student skills categorization, and course success level, after conducting an interview, focused group discussion, and evaluations with experts. This method includes performance indicators and acceptance criteria via Course Learning Outcome value, Course Learning Outcome level, Course Success Rate level, and student skills, which operate at the study program's course level. The researchers performed the overall attainment process using the direct attainment method. The measurement model proposed has been successfully accepted and implemented in 7 study programs in 11 universities in Indonesia.
Keywords: Attainment; course outcome; outcome-based education; student categorization; student skills.
Social Protection and Conflict-Sensitivity Directions for Mozambique
Authors: Oosterom Marjoke , Alcorta Ludovico
Published: September 2024

This report contains an overview of the main conflict-sensitive concerns for social protection programmes and implementation modalities in Mozambique at the regional, local, and programme levels. Key concerns include issues around: (1) targeting, registration, and payment issues due to errors and delays and/or lack of understanding of eligibility criteria, and dynamics between host and displaced communities; (2) inadequate complaint and grievance mechanisms; (3) limited coordination between implementing actors; (4) insecurity caused by the NSAG; (5) fear and trauma reported by staff and beneficiaries; and (6) potential sexual and gender-based violence dynamics due to mobile payments.
Resiliência dos enfermeiros no cuidado ao doente crítico COVID-19
Authors:   Centro Hospitalar de Trás-os-Montes e Alto Douro, Alves Rute , Antunes Cristina ,   Escola Superior de Saúde/ Universidade de Trás-os-Montes e Alto Douro, Imaginário Cristina ,   Nursing School of Porto
Published: September 2024

Contexto: Os enfermeiros, enquanto profissionais na prestação de cuidados ao doente COVID-19, estiveram expostos a um maior risco de vulnerabilidade. Objetivo: Identificar o nível e fatores de resiliência e analisar a sua relação com as caraterísticas sóciodemográficas e profissionais dos enfermeiros. Metodologia: Realizou-se um estudo de natureza quantitativa, descritiva, correlacional e transversal. A amostra foi constituída por 60 enfermeiros do serviço de urgência geral de adultos de um hospital da região norte do país. Para a recolha de dados recorreu-se a um questionário para a caraterização sociodemográfico e profissional e a Escala de Resiliência para Adultos. Foi realizado o tratamento estatístico descritivo e inferencial, com recurso ao programa IBM-SPSS® versão 25.0. Resultados: Os enfermeiros mostraram um nível de resiliência acima do valor médio da escala e foram os enfermeiros do sexo feminino que apresentam maiores níveis de resiliência. Referiram o fator Recursos Sociais como o mais frequente e o fator Estilo Estruturado como o menos frequente. Conclusões: Os resultados mostram um nível de resiliência dos enfermeiros acima do valor médio da escala. Altos níveis de resiliência podem ser explicados pela Teoria de Reintegração Resiliente na qual o confronto com a adversidade resulta em novos patamares de crescimento e adaptação pessoal.
Impacto psicológico na equipe do SAMU 192 durante pandemia COVID-19
Authors:   Serviço de Atendimento Móvel de Urgência, Almeida Priscila Masquetto Vieira de , Domingues Lívia Prando ,   Universidade Estadual Paulista, Novelli e Castro Meire Cristina ,   Universidade Estadual Paulista
Published: September 2024

Introdução: O Serviço de Atendimento Móvel de Urgência - SAMU 192 é o componente pré-hospitalar móvel instituído pelo Ministério da Saúde no Brasil. Com a pandemia COVID-19, o serviço passou a atender os pacientes acometidos pela doença. Esse cenário trouxe grande tensão para os profissionais, o que tornou relevante compreender as alterações psicológicas vivenciadas pela equipe, a fim de proporcionar uma assistência psicológica adequada e o bem-estar aos mesmos. Objetivo: Analisar os níveis de depressão, ansiedade e estresse na equipe do SAMU 192. Metodologia: Estudo transversal, exploratório-descritivo, com abordagem quantitativa. Aplicou-se a versão reduzida da escala Depression, Anxiety and Stress Scale‐21 (DASS-21) na equipe do SAMU 192, uma escala tipo Likert de quatro pontos que avalia os níveis de depressão, ansiedade e estresse. Resultados: Participaram da pesquisa 54 profissionais do SAMU 192, 78,8% da equipe total. A média de idade foi de 37,41 anos, sendo a maioria do sexo feminino. A maioria dos profissionais apresentaram níveis normais de depressão, ansiedade e estresse, entretanto, os casos de alterações representaram 27,77%, 24,08% e 18,51% respectivamente. Houve maior risco de estresse entre os profissionais que realizam plantão noturno, maior risco de ansiedade em técnicos de enfermagem e em profissionais que trabalham no período diurno ou folguistas e depressão em técnicos de enfermagem. Conclusão: Os níveis de estresse, ansiedade e depressão encontrados no estudo foram baixos, o que difere do esperado e pode estar relacionado a fatores protetores como a satisfação e identificação com o trabalho. Se houver secções dentro do resumo devem estar a negrito e iniciar-se numa nova linha
Aperçu sur les études de répartition des essences forestières tropicales américaines
Authors: Budowski Gerardo
Published: September 2024

Les cartes de répartition des arbres des forêts tropicales américaines sont rares et généralement peu utiles. Cela peut s'expliquer par la grande variété des conditions environnementales qui changent fréquemment sur de petites surfaces. Des connaissances beaucoup plus approfondies sur l'écologie des arbres sont nécessaires pour comprendre leur schéma de distribution.L'influence des facteurs environnementaux classés en influences climatiques, édaphiques et biotiques, en tenant compte des changements passés, est soulignée pour expliquer les schémas de distribution.Les facteurs climatiques actuels sont globalement importants car les plantes se limitent généralement à un certain environnement mieux défini par des limites de température et de pluviométrie. Les exceptions sont les espèces pionnières ou les espèces spécialement adaptées pour prospérer et se reproduire dans des conditions particulières, défavorables à la plupart des autres espèces.Des changements climatiques nuisibles ont eu lieu et leur impact sur la distribution est discuté. Ils permettent souvent d'expliquer la présence de nombreuses espèces.Les différences réelles des facteurs édaphiques expliquent des schémas de distribution très spécialisés. L'origine géologique et les relations de drainage, comme celles que l'on trouve dans le bassin de l'Amazone, expliquent d'importantes variations.Parmi les facteurs biotiques, l'homme et, avec lui, le feu, sont d'une importance primordiale. Les espèces pionnières et résistantes au feu, notamment le pin, sont favorisées. L'influence des animaux sauvages et domestiques n'est pas bien connue, bien qu'ils puissent être à l'origine de la dispersion de nombreuses graines.
NEW RECORDS OF CICADULINA BIPUNCTATA (MELICHAR, 1904) (HEMIPTERA CICADELLIDAE) FROM SPAIN AND ITALY AND UPDATE ON ITS DISTRIBUTION IN EUROPE
Authors: CASIRAGHI ALICE , POGGI FRANCESCO
Published: September 2024

The leafhopper Cicadulina bipunctata (Melichar, 1904), native to northern and eastern Africa and hitherto collected in Europe only in Greece, Italy (Sicily) and Spain (Andalusia), was also found in Sardinia and Calabria (Italy) and its occurrence in the Spanish province of Alicante was confirmed. Its European distribution is updated, also considering data obtained by tracking via internet photo sharing websites. Its possible range expansion in Europe, habitat, and phytosanitary issues are explained and discussed. Key Words: Auchenorrhyncha, Deltocephalinae, range expansion, Poaceae pathogen vector
IMPROVING THE KNOWLEDGE OF SOUTH ITALIAN MICROLEPIDOPTERA: SPILOMELINAE (LEPIDOPTERA CRAMBIDAE) FROM CALABRIA WITH A FOCUS ON FORESTED HABITATS
Authors: LA CAVA SARA , RIJLLO GIUSEPPE , ZUCCO GIADA , SCALERCIO STEFANO
Published: September 2024

In this paper we reported the faunistic data concerning the subfamily of Spilomelinae (Crambidae) collected in several sites, almost throughout the Calabria region. The specimens were identified at species level by morphological comparison and a sample of it was submitted to DNA barcoding. Difficult species were dissected and identified based on morphological analysis of their genitalia. In this paper we provide new distribution data for 30 species of Spilomelinae, increasing the knowledge of this group in South Italy and in the Calabria region. Particularly interesting are the results concerning Metasia suppandalis (Hübner, 1823), new for peninsular Italy and Metasia rosealis Ragonot, 1895 reported only twice for Italy, so far. We also reported 13 species new for the microlepidopteran fauna of the region. In addition, we reported Nomophila noctuella (Denis & Schiffermüller, 1775), a very common species, only reported for Calabria in 1863 and Hydriris ornatalis (Duponchel, 1832) only reported for the region in the year of 2000. Key Words: biodiversity, DNA barcoding, new records, forests, crambid snout moths
ANALISIS TINGKAT KESULITAN KEUANGAN TERHADAP TINGKAT HUTANG DENGAN DEWAN KOMISARIS INDEPENDEN SEBAGAI VARIABEL INTERVENING (Studi Pada Perusahaan Sub Sektor Pertambangan yang Terdaftar di BEI)
Authors: Hayati Sirrul , Atmayanti Tati
Published: September 2024

This study aims to analyze the relationship between the level of Financial Distress and the Level of Debt with the Independent Board of Commissioners as an Intervening Variable. The type of research used in this research is quantitative and then processed with statistical methods. The population in this study are all companies in the mining sector which are listed on the Indonesia Stock Exchange (IDX). The sampling technique in this study was purposive sampling. Data analysis techniques using descriptive statistics, classic assumption test, multiple regression, hypothesis testing.
Based on the results of data processing and data analysis in this study, it was found that financial distress had a positive and significant effect on debt levels, financial difficulties had a positive and significant effect on independent commissioners, independent commissioners had no significant effect on debt levels, independent commissioners were unable intervene the effect of financial difficulties on debt levels. In this study, financial difficulties and an independent board of commissioners have a joint effect of around 62.3% on debt levels.
This study aims to analyze the relationship between the level of Financial Distress and the Level of Debt with the Independent Board of Commissioners as an Intervening Variable. The type of research used in this research is quantitative and then processed with statistical methods. The population in this study are all companies in the mining sector which are listed on the Indonesia Stock Exchange (IDX). The sampling technique in this study was purposive sampling. Data analysis techniques using descriptive statistics, classic assumption test, multiple regression, hypothesis testing.
                Based on the results of data processing and data analysis in this study, it was found that financial distress had a positive and significant effect on debt levels, financial difficulties had a positive and significant effect on independent commissioners, independent commissioners had no significant effect on debt levels, independent commissioners were unable intervene the effect of financial difficulties on debt levels. In this study, financial difficulties and an independent board of commissioners have a joint effect of around 62.3% on debt levels.
LITERACY, TRUST, AND RISK AFFECT SHARIA FINTECH FINANCING INTENTIONS ON UMKM ACTORS IN CENTRAL JAVA
Authors: Mu'afifah Luluk , Sukardi Budi
Published: September 2024

This study aims to determine and analyse the effect of literacy, trust, and risk on financing intentions through Sharia Fintech on MSME players in Boyolali district, Central Java. The sampling technique used is purposive sampling with predetermined respondent criteria. This study uses a quantitative research method using a questionnaire through Google Forms as an online data collection material. The sample used in this study was 226 respondents of MSME players in Boyolali Regency. The test results with SEM-PLS prove that several factors have a positive and significant effect, namely the variables of trust and risk. On the other hand, there are variables that do not affect the literacy variable on Islamic fintech financing intentions.
Machine learning applications in adult spinal deformity corrective surgery: a narrative review
Authors: Toossi Nader , Jerry Ozhan
Published: September 2024

Adult spinal deformity (ASD) poses significant challenges in spinal surgery, requiring precise planning and execution for successful correction. Additionally, optimization of outcomes and reducing the high complication rates of ASD surgeries are additional challenges facing spinal deformity surgeons. The advent of machine learning (ML) has revolutionized various aspects of healthcare, including spinal surgery. This review provides a comprehensive overview of the current state of ML applications in spinal deformity corrective surgery, highlighting its potential benefits and challenges.
Optimalisasi Fungsi ASEAN Intergovernmental Commission on Human Rights (AICHR) dan Tantangan Perlindungan Hak Asasi Manusia di Asia Tenggara
Authors: Sigit Riyanto
Published: September 2024

Pursuant to the 2008 Charter, ASEAN has worked with a new legal framework and has thus established various organs to accelerate the process of community building. In accordance with the said Charter, ASEAN established a Human Rights Body namely the ASEAN Intergovernmental Commission on Human Rights (AICHR). AICHR serves as a human rights institution which is designated as an integral part of ASEAN that is responsible for promoting and protecting human rights according to the objectives and principles in the ASEAN Charter. In the light of their human rights protection efforts, AICHR has exhibited promising achievements. On the other hand, however, AICHR is considered ineffective as it has not achieved significant results in terms of protecting and upholding human rights in Southeast Asia. This research is intended to conduct a critical study of the role and function of AICHR in dealing with contemporary human rights problems and challenges. By observing the contemporary human rights problems and challenges in Southeast Asia, it is strongly recommended that ASEAN immediately adjust and expand the mandate of the AICHR. Adjusting and expanding AICHR's mandate can strengthen AICHR's structure and authority as an institution that safeguards human rights in Southeast Asia. Strengthening the AICHR will contribute to the protection and upholding of human rights and increase ASEAN's credibility as a Regional Organization.Keywords: AICHR, ASEAN, Enforcement, Human Rights, Protection.
AbstrakBerdasarkan Piagam tahun 2008, ASEAN bekerja dengan kerangka hukum baru dan membentuk berbagai organ yang diperlukan untuk mempercepat proses membangun komunitas. Sesuai dengan Piagam, ASEAN membentuk Badan HAM yang dinamai ASEAN Intergovernmental Commission on Human Rights (AICHR). AICHR merupakan lembaga HAM yang dirancang sebagai bagian integral ASEAN yang bertanggungjawab dalam upaya promosi dan perlindungan HAM. Sesuai dengan tujuan dan prinsip-prinsip di dalam Piagam ASEAN. Dalam upaya promosi HAM, AICHR telah membuktikan capaian yang menjanjikan, namun, dalam hal perlindungan dan penegakan HAM, AICHR dianggap belum efektif. AICHR belum mencapai hasil yang signifikan dalam hal perlindungan dan penegakan HAM di Asia Tenggara. Penelitian ini dimaksudkan untuk melakukan kajian kritis tentang peran dan fungsi AICHR dalam menghadapi permasalahan dan tantangan HAM kontemporer. Mencermati permasalahan dan tantangan HAM kontemporer di Asia Tenggara, sangat disarankan ASEAN segera melakukan penyesuaian dan perluasan mandat AICHR. Penyesuaian dan perluasan mandat AICHR dapat memperkuat struktur dan otoritas AICHR sebagai institusi pengawal HAM di Asia Tenggara. Penguatan AICHR akan berkontribusi pada perlindungan dan penegakan HAM serta meningkatkan kredibilitas ASEAN sebagai Organisasi Regional.Kata Kunci: AICHR, ASEAN, Hak Asasi Manusia, Penegakan, Perlindungan.
Epidermal Compounds Analyse and Diagnosis
Authors: CHESCA ANTONELLA
Published: September 2024

The purpose of the study is to analyse and to identify specific structural characteristics of melanocytic nevi, to youth pacients. Using the optical microscope, could be possible a proper describtion related melanocytic nevi. In this study play a significant role, different factors, such as genetic, epigenetic, microbiomic and proteomic factors. Future directions refers to preventive and prophylactic methods. Disease diagnostic and management directions are also important key points.
Health Literacy and Patient Activation Level among Glaucoma Patients: A Cross-Sectional Study in Greece
Authors: Tsichla Lοukia , Patelarou Evridiki , Detorakis Efstathios T , Tsilimbaris Miltiadis K. , Patelarou Athina , Giakoumidakis Konstantinos
Published: September 2024

Background: Chronic diseases are major causes of morbidity, disability, and death worldwide. In many cases, they are potentially preventable and treatable. Glaucoma is one of the leading causes of morbidity and blindness, the early recognition of which can help reduce the adverse outcomes of the disease. Health illiteracy among these patients and the absence of self-management of these diseases are barriers to effective management worldwide. Therefore, the present study aimed to calculate the level of health literacy and activity level of patients’ activation in self-management and to explore the link between them among patients with glaucoma in outpatient clinics. Material and methods: Convenience sampling of patients with glaucoma attending the outpatient ophthalmology clinics of a university hospital in Heraklion-Greece was performed. Convenience sampling was used to recruit 312 participants. Data were collected between November 2023 and May 2024. The Patient Activation Measure-13 (PAM-13) questionnaire, in its Greek version, was used to evaluate patients’ activation level in self-management, whereas the Greek version of the European Health Literacy Survey Questionnaire 16 (HLS-EU-16) was used to assess health literacy. Results: Participants were classified as level 1(disengaged & overwhelmed) level in self-management (= 40.7, SD: ±29.9) and a sufficient health literacy level (= 10.7, SD ±3.7). However, there was no statistically significant relationship between health literacy levels and patient activation in self-management (p=0.602). Conclusions: Glaucoma patients experience challenges with health literacy and self-management activation, though there is no significant relationship between these two parameters. Multifaceted interventions seem essential for enhancing patients’ activation. Further research involving larger sample sizes, multi-center studies, and interventional design is needed.
Integrating RFID and Blockchain for Recycling Empty Medication Bottles in the Pharmaceutical Industry
Authors: Ali Syed Adnan
Published: September 2024

The growing emphasis on sustainability and environmental stewardship in the pharmaceutical industry necessitates innovative solutions to manage pharmaceutical waste, particularly medication bottles. This research paper explores the potential of integrating Radio Frequency Identification (RFID) and blockchain technology to enhance the traceability, accountability, and efficiency of recycling empty medication bottles. By utilizing RFID for real-time tracking and blockchain for secure, immutable data storage, this proposed system improves transparency across the supply chain and incentivizes consumer participation in recycling programs. The solution provides benefits to pharmaceutical manufacturers, regulators, and consumers, contributing to sustainability, regulatory compliance, and environmental protection.
Generative AI in Academics
Authors: Schultz Brittney
Published: September 2024

There is a bifurcation in the academic voice regarding the adoption or rejection of generative AI in the classroom. This division in pedagogy remains ever present as educators struggle to catch up with advancing AI technology and its staunch integration into student’s everyday lives. A resounding concern from educators is for the authenticity of student work and the building of critical thinking skills, both of which become threatened by generative AI tools used without proper guidelines. Educators have a right to these concerns, as studies continue to show how generative AI tools successfully pass assessments and how the AI-coauthored work is challenging to detect or differentiate from student-authored work. In the field of Computer Science, the challenges compound as generative AI technology integrates seamlessly into already approved code-generation tools and development environments. Therefore, an informed and thoughtful decision must be made so that student learning can continue to flourish and evolve in a safe and inclusive setting. This research attempts to go beyond introductory course assessments, where a gap in research currently hangs. As curriculum becomes more challenging and abstract, can generative AI continue to pass assessments and be useful educational assistants? Or will these tools create more confusion for students as prompts become more advanced and prove difficult to interpret? During this empirical study, GitHub Copilot is assessed against the assessments of an advanced CS programming course. The findings present a resounding optimism for generative AI tools, with all assessments passed successfully. The study concludes with recommending an integrated approach of introducing and encouraging the use of generative AI. Collaboration with a partnership mindset will produce the best results.
Automatic Assist Level Adjustment Function of a Gait Exercise Rehabilitation Robot with Functional Electrical Stimulation for Spinal Cord Injury
Authors: Kimura Ryota , Sato Takahiro , Kasukawa Yuji , Kudo Daisuke , Iwami Takehiro , Miyakoshi Naohisa
Published: September 2024

This study aimed to identify whether the combined use of functional electrical stimulation (FES) reduces the motor torque of a gait exercise rehabilitation robot in spinal cord injury (SCI) and to verify the effectiveness of the developed automatic assist level adjustment in people with paraplegia. Acute and chronic SCI patients (1 case each) performed 10 min of gait exercises with and without FES using a rehabilitation robot. Reinforcement learning was used to adjust the assist level automatically. The maximum torque values and assist levels for each of the ten walking cycles when walking became steady were averaged and compared with and without FES. The motor's output torque and the assist level were measured as outcomes. The assist level adjustment allowed both the motor torque and assist level to decrease gradually to a steady state. The motor torque and the assist levels were significantly lower with the FES than without the FES under steady conditions in both cases. No adverse events were reported. The combined use of FES attenuated the motor torque of a gait exercise rehabilitation robot for SCI. Automatic assistive level adjustment is also useful for spinal cord injuries.
19G EUS-FNA versus 22G EUS-FNB for Pancreatic Tumors: A Retrospective Comparative Study
Authors: Katsukura Nobuhiro , Doi Shinpei , Hayakawa Jun , Okamoto Kanji , Akutsu Tomohiro , Namura Yuta , Saito Go , Kikuyama Tomohiro , Adachi Takako , Matsumoto Kotaro , Watanabe Ayako , Tsunashima Hiromichi , Tsujikawa Takayuki , Aso Tatsuya , Takahashi Mikiko
Published: September 2024

BACKGROUND: Endoscopic ultrasound-guided tissue acquisition (EUS-TA) is essential technique for sampling solid pancreatic lesions. However, the optimal needle type for achieving high histological diagnostic capability remains unclear. This study compares the histological diagnostic capabilities of the 19G FNA needle and the 22G FNB needle for solid pancreatic lesions.
METHODS: This single-center, retrospective study was conducted in patients who underwent EUS-TA for solid pancreatic lesions. Patients were allocated to either Group A, utilizing the 19G FNA needle, or Group B, utilizing the 22G FNB needle. The primary outcome was the diagnostic accuracy based on histology alone.
RESULTS: 143 patients were analyzed, with 61 in Group A and 82 in Group B. Diagnostic accuracy was significantly higher in Group B for both histology alone (85.4% vs. 68.9%, p=0.02) and overall diagnostic accuracy (85.4% vs. 73.8%, p=0.02). Logistic regression analysis revealed that lesion size ≥25 mm was an independent factor contributing to higher diagnostic accuracy (OR 3.32, 95% CI 1.28-8.64, p=0.01). Subgroup analysis showed that diagnostic accuracy for 15–25 mm lesions was significantly higher in Group B (90.0% vs. 63.2%, p=0.02). Additionally, trans-gastric punctures had higher accuracy in Group B (94.7% vs. 73.5%, p=0.01).
CONCLUSIONS: Our study showed the overall superiority of the 22G FNB needle for EUS-TA of solid pancreatic lesions. However, 19G FNA needle remains a valuable option under specific conditions.
Enhancing Supply Chain Efficiency with Time Series Analysis and Deep Learning Techniques
Authors: Sun Jun , Zhou Shuwen , Zhan Xiaoan , Wu Jiang
Published: September 2024

Accurate forecasting and efficient management of commodities are crucial for stakeholders in the industry, given the volatile nature of these markets. This study addresses these needs by leveraging advanced forecasting techniques and machine learning models to predict prices and enhance supply chain efficiency. TThe focus is on utilizing ARIMA, SARIMAX, and LSTM models to analyze historical trading data for commodities such as cocoa, coffee, and sugar sourced from Kaggle’s comprehensive dataset. The research applies ARIMA and SARIMAX models to forecast price trends, overcoming initial challenges related to data index frequency and seasonality. LSTM models are employed for more nuanced demand forecasting, particularly for random-length lumber, demonstrating the model's capability to predict future market trends accurately. The study highlights significant improvements in prediction accuracy and supply chain management through meticulous feature engineering and model optimization, offering valuable insights for strategic decision-making in the supply chain sector.
Development of a Sensitive and Reliable Immunoassay to Quantify TDP-43 in Human Biofluids
Authors: An Jiyan , Gopalakrishnan Lathika , Ortega Vanessa , Saul Justin , Kadali Renu , Bowser Robert
Published: September 2024

Transactive response DNA-binding protein of 43 kDa (TDP-43) is a major component of pathological inclusions in various neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). The detection of TDP-43 in biofluids is crucial for the development of diagnostic and prognostic indicators of disease and therapeutic development for TDP-43 related proteinopathies. Despite its potential as a biomarker for numerous neurological disorders, the lack of a sensitive and reproducible TDP-43 assay hinders progress in TDP-43-based therapy development, underscoring the need for an effective and standardized method for accurate quantification. In this study, we developed and validated a sensitive immunoassay for the detection of TDP-43 in human biofluids using the Meso Scale Discovery (MSD) platform. We used this immunoassay to quantify TDP-43 levels in the plasma and serum of healthy controls and ALS patients. Our results indicate a reduction of total TDP-43 in the blood of ALS patients compared to healthy controls.
The Impact of Big Data on SME Performance: A Systematic Review
Authors: Kgakatsi Mpho , Galeboe Onthatile , Molelekwa Kopo , Thango Bonginkosi
Published: September 2024

In recent years, Big Data (BD) has become a crucial tool for Small and Medium-sized Enterprises (SMEs), impacting their performance and growth in significant ways. This systematic literature review aims to analyze the effects of BD on SMEs by examining 93 research papers published from 2014 to 2024. Employing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) framework, the review focuses on key drivers and barriers to BD adoption, including business improvement, economic performance, and revenue growth. The methodology involved a comprehensive analysis of research methodologies used in the studies, addressing biases, gaps, and the need for diverse approaches. The findings reveal that while BD has led to notable enhancements in operational efficiency and revenue for many SMEs, challenges such as limited resources and technical expertise remain. A significant reporting bias was observed, with 47% of the literature comprising quantitative studies, followed by 28% case studies, while mixed-methods and qualitative studies were underrepresented (22% and 17%, respectively). This imbalance suggests a potential overemphasis on quantitative approaches, limiting the diversity of insights available. Addressing these biases is essential to fully harness the potential of BD for SMEs to drive innovation, enhance competitiveness, and achieve better performance in the increasingly data-driven business environment.
Machine Learning Analysis of Factors Influencing Pediatric Telehealth Visits During COVID-19: A State-Level Comparison Using 2021-22 National Survey of Children’s Health Data
Authors: Lee Yu-Sheng , Shrestha Junu , Sprong Matthew Evan , Huang Xueli , Tuladhar Sushil , Chuang Michael Y
Published: September 2024

Background/Objectives:
The COVID-19 pandemic reduced in-person pediatric visits in the United States by over 50%, while telehealth visits increased significantly. The national use of telehealth for children and the factors influencing its use have been rarely studied. This study aimed to investigate the prevalence of telehealth use during the COVID-19 pandemic and explore the potential factors linked to its use at the state level.

Methods:
A cross-sectional study of the National Survey of Children’s Health (2021-22) sponsored by the federal Maternal and Child Health Bureau was performed. We used the least absolute shrinkage and selection operator (LASSO) regression to predict telehealth use during the pandemic. A bar map showing the significant factors from the multivariable regression was created.

Results:
Of the 101,136 children, 15.25% reported using telehealth visits due to COVID-19, and 3.67% reported using telehealth visits due to other health conditions. The Northeast states showed the highest telehealth use due to COVID-19. In the Midwest and Southern states, children had a lower prevalence of telehealth usage unrelated to COVID-19. The LASSO regressions demonstrated that telehealth usage (due to and not due to) was associated with age, insurance type, household income, usual source of pediatric preventive care, perceived child health, blood disorders, allergy, brain injury, seizure, ADHD, anxiety, depression, and special needs.

Conclusions:
This study demonstrated significant variability in the use of telehealth among states during the COVID-19 pandemic. Understanding who uses telehealth and why, as well as identifying access barriers, helps maximize telehealth potential and improve healthcare outcomes for all.
Growth Promotion and Economic Benefits of the Probiotic Lactiplantibacillus plantarum in Calves
Authors: Osawa Kazumasa , Taharaguti Saya , Ito Chiaki , Takino Tadashi , Hagiwara Katsuro
Published: September 2024

Various measures have been attempted to prevent infectious diseases in calves, such as envi-ronmental improvement and vaccine administration. Probiotics are commonly used to im-prove the body condition of newborn calves and prevent disease. In our previous research, Lactiplantibacillus plantarum RGU-LP1 (LP1) inhibited the expression of inflammatory cyto-kines in PBMC from cows fed LP1. In this study, we evaluated the effect of LP1 on calf growth and disease control. Methods: Twenty-six one-week-old Holstein bull calves were divided into two groups (13 each), LP1 group (LP1 treated) and CN group (no LP1 fed), and tested as follows. The LP1 group was fed lyophilised LP1 (10⁹ CFU/head/day) in milk replacer for 40 days. The CN group was fed the same diet only. Calves were followed for 63 days. During this period, the weight and treatment times of the calves were recorded. Faeces and blood were collected from each calf during this period. Faeces were examined for gut microbiota, and blood for immune assay and cytokine gene expression. The LP1-treated group showed a de-crease in disease incidence and an increase in body mass compared to controls. Results: The average treatment cost during the observation period was significantly reduced compared to the CN group. The expression of TGFβ and IL10, inhibitory cytokines of inflammation, was sig-nificantly increased. The simultaneous expression of this set of inhibitory molecules resulted in low serum IL1β levels during the growth period. Conclusions: The Th1-type cytokine IFNγ was also significantly increased in LP1-treated calves. By reducing the number of disease treatment times and increasing body weight, LP1 is effective in preventing infectious diseases in calves. In addition, the increase in IFNγ by LP1 indicates improved Th1-type immunity in calves. These results show that LP1 has effects on the regulated inflammatory response and growth of calves.
Knee Joint Response to Mechanical Loading: Bounding Mechanotransduction with Rehabilitation
Authors: Kacprzak Bartłomiej , Stańczak Mikołaj
Published: September 2024

The knee joint plays a vital role in human movement, bearing mechanical loads during daily and athletic activities. This review explores the knee joint's response to mechanical loading, particularly focusing on mechanotransduction—the process by which cells convert mechanical stimuli into biochemical signals. These signals trigger cellular responses crucial for maintaining joint health, promoting repair, and adapting to mechanical changes.
Understanding mechanotransduction is key to developing effective rehabilitation strategies for knee injuries and managing conditions like osteoarthritis. This review synthesizes current research on the cellular and molecular pathways involved in knee joint mechanotransduction, examining how various loading conditions—such as compression, tension, and shear—affect tissues like cartilage, synovium, ligaments, and tendons.
The review discusses the impact of mechanotransduction on cellular components such as chondrocytes, synoviocytes, and fibroblasts, which are essential for maintaining tissue integrity and function. It also highlights the role of signaling pathways like MAPK, NF-κB, and Wnt in mediating cellular responses to mechanical stimuli, influencing gene expression, protein synthesis, and metabolism.
By understanding these mechanisms, clinicians can develop targeted therapeutic interventions, including controlled loading protocols, exercise regimens, and manual therapies. This review underscores the importance of integrating mechanobiology insights into rehabilitation practices to enhance tissue repair, restore function, and prevent further joint degeneration, ultimately improving knee joint health and patient outcomes.
Comparative Evaluation of Lipid Profile, C-reactive Protein and Paraoxonase-1 Activity in Dogs with Inflammatory Protein-Losing Enteropathy and Healthy Dogs
Authors: Gianella Paola , Cagnasso Federica , Giordano Alessia , Borrelli Antonio , Bottero Enrico , Bruno Barbara , Ferriani Riccardo , Borella Franca , Meazzi Sara , Scavone Donatella , Paltrinieri Saverio
Published: September 2024

Chronic inflammation alters lipoprotein metabolism and causes changes in serum concentrations of lipids, C-reactive protein (CRP), and paraoxonase-1 activity (PON-1), an enzyme, which in the gastrointestinal tract may act as a local detoxifier, antioxidant, and immunomodulator. However, unlike in people with inflammatory bowel disease, scarce information is available in dogs with protein-losing enteropathy secondary to chronic inflammatory enteropathy (iPLE). The first aim was to describe and compare the lipid profile, CRP concentrations and PON-1 activity in healthy dogs and in dogs with iPLE. The second aim was to evaluate correlations among clinicopathological, histologic data, and lipid profiles in dogs with iPLE. Serum samples from 51 iPLE and 40 healthy dogs were used to study albumin, total protein, CRP, PON-1 activity, cholesterol, triglycerides, and lipoprotein classes obtained by electrophoretic separation. There was a significant difference of all serum analytes between iPLE and healthy dogs. Significant correlations between the lipid profile and the existing chronic enteropathy activity index were not found. Some lipoprotein classes correlated with CRP and PON-1. Triglycerides were significantly higher in dogs with both inflammation and lymphangiectasia. Lipoproteins, CRP and PON-1 activity are altered in dogs with iPLE. Results need to be confirmed in further studies.
Role of Humic Substances in the (Bio)degradation of Synthetic Polymers under Environmental Conditions
Authors: Senko Olga , Maslova Olga , Stepanov Nikolay , Aslanli Aysel , Lyagin Ilya , Efremenko Elena
Published: September 2024

Information on the detection of the presence and potential for degradation of synthetic polymers (SPs) under various environmental conditions is of increasing interest and concern to a wide range of specialists. At this stage, there is a need to understand the relationship between the main par-ticipants in the processes of (bio)degradation of SPs in various ecosystems (reservoirs with fresh and sea water, soils, etc.), namely the polymers themselves, the cells of microorganisms (MOs) partici-pating in their degradation, and humic substances (HSs), which constitute a macrocomponent of natural non-living organic matter of aquatic and soil ecosystems, formed and transformed in the processes of mineralization of bioorganic substances in environmental conditions. Analysis of the main mechanisms of their influence on each other and the effects produced that accelerate or inhibit polymer degradation can create the basis for scientifically based approaches to the most effective solution to the problem of degradation of SPs, including in the form of microplastics. This review is aimed at comparing various aspects of interactions of SPs, MOs and HSs in laboratory experiments (in vitro) and environmental investigations (in situ) aimed at the biodegradation of polymers, as well as pollutants (antibiotics and pesticides) that they absorb. Comparative calculations of deg-radation velocity of different SPs in different environments are presented. A special place in the analysis is given to the elemental chemical composition of HSs, which are most successfully in-volved in the biodegradation of SPs. In addition, the role of photooxidation and photoaging of polymers under the influence of the ultraviolet spectrum of solar radiation under environmental conditions on the (bio)degradation of SPs in the presence of HSs is discussed.
Unveiling the Nutrient Signatures in Corn (Zea Mays L.) Grains: A Pivotal Indicator of Yield Potential
Authors: Ismail Nour , Khiari Lotfi , Daoud and Rachid
Published: September 2024

The composition simplex (N, P, K, Ca, and Mg) of the leaf is the main scores used by different approaches like the Diagnosis and Recommendation Integrated System and Compositional Nutrient Diagnosis to study the nutrient interactions and balance in plant leaves.
However, the application and validation of these concepts to grain composition remains unexplored. Contrary to foliar analysis's early intervention for nutrient deficiency detection and correction, applying this approach to seeds assesses diverse cultivars' potential, enabling anticipation of their adaptation to climate conditions and informed selection for future crops.
In the present study, a collected database of more than 924 scores including the grain yield (kg ha-1) and the nutrient composition (mg kg-1) of different corn varieties is used to develop a novel nutrient-based diagnostic approach to identify reliable markers of nutrient imbalance. A 'nutrient signature' model is proposed based on the impact of the environ-mental conditions on the nutrient indices and composition (N, P, K, Ca, and Mg) of the corn grains.
The yield threshold used to differentiate between low and high-yielding subpopulations is established at 12.000 kg ha-1and the global nutrient imbalance index (GNII) of 2.2 is determined using the chi-square distribution function and vali-dated by the Cate-Nelson partitioning method, which correlated yield data distribution with the GNII. Therefore, the nutrient compositions were classified into highly balanced (GNII ≤ 1.6), balanced (1.6 < GNII ≤ 2.2), and imbalanced (GNII > 2.2). In addition, we found that the Xgboost model's predictive accuracy for GNII is signif-icantly affected by soil pH, organic matter, and rainfall.
These results pave the way for adapted agricultural practices by providing insights into the nutrient dynamics of corn grains under varying environmental conditions.
Privatización y financiamiento a la demanda: respuestas neoliberales para desregular el Sistema de Educación Pública de Argentina
Authors: Seoane Viviana I. , Carriquiriborde Nicolás
Published: September 2024

En el presente artículo proponemos analizar el impacto de la desregulación total y desfinanciamiento del Estado en lo que respecta al campo de la educación reponiendo parcialmente las propuestas contenidas en el primer Decreto de Necesidad y Urgencia (70/23) presentado por el actual gobierno de Javier Milei a días de asumir, y en la posterior Ley Bases presentada al Congreso Nacional para su aprobación. Partimos de analizar de qué modos este proyecto político afecta el Derecho a la Educación en tanto Derecho Humano dado que observamos una relación que el actual gobierno vino a profundizar entre neoliberalismo y mercantilización y privatización de la educación. Uno de los mecanismos para alcanzar este propósito es la propuesta de instalar el financiamiento a la demanda, entre ellas el voucher o cupón educativo, y arancelar la educación superior. El análisis de los principales instrumentos políticos (DNU y Ley Bases) nos permiten esbozar el riesgo que supone modificar el sustrato político ideológico en el que se sustenta la educación pública en nuestro país como derecho social. Como parte de las “nuevas derechas”, “derechas extremas” o “derecha radical”, el gobierno de Javier Milei avanza bajo un régimen de crueldad cuyas prácticas sociales cuestionan los principios igualitarios de la democracia.