bluuebunny/crossref_metadata_2025 huggingface dataset:
Role of Interleukin-8 with Special Progress of Atopic Dermatitis
Authors: Khan Muhammad Noman
Published: January 2023

Atopic dermatitis (AD) is a recurrent pruritic chronic inflammatory skin disease, also known as atopic eczema and neurodermatitis sown. Its actual cause is still unknown, but association of disease progression may be related to immune system abnormalities. Many studies reported that AD lesions are linked with mainly increased no. of T lymphocytes with other inflammatory cells including monocytes, eosinophils and macrophages. T Lymphpocytes mediate inflammation and local immune response by secondary antibody production which are involved in cell-mediated immunity and delayed type hypersensitivity inflammatory reactions. IL-8 which is a proinflammatory cytokine and have high chemotactic activity on neutrophils, T lymphocytes and basophils along with activation of proinflammatory cells to perform immune functions. High expression of IL-8 was also reported in AD lesions which can cause chemotaxis, aggregation and activation of inflammatory cells. It also promotes IL-4 and IL-3 overexpression resulting in the proliferation and differentiation of mast cells which further aggravates AD. Here, in this manuscript IL-8 and related cytokines involved in atopic dermatitis pathogenesis and progression are reviewed more than spring season in dogs.
Production Optimization and Industrial Applications of Amylase From Indigenous Bacterial Species Using Banana Peels
Authors: Madiha Muhammad Fazil  , Iqra Javed  , Kiran Ali  , Humera Waheed  , Nida Dastagir
Published: January 2023

Introduction: Alpha amylases are starch hydrolyzing enzymes that possess high industrial demand. Various strategies have been adopted to enhance cost-effective enzyme production of which utilization of agro-industrial waste is very promising. Methodology: In this study two amylase producers Bacillus megaterium and Exiguobacterium auranticum were isolated and identified by 16sRNA sequencing their growth conditions were optimized via submerged fermentation using banana peels as carbon source. Bacillus megaterium found to be mesophilic alkaline (37℃, pH of 9) strain giving 472 U/ml while Exiguobacterium auranticum found to be acidic thermophilic (50°C, pH 5) that gave 391 U/ml. Results and Conclusion: Production of amylase by acidic thermophilic E. auranticum is reported here for the first time. The crude enzyme also showed better chocolate and curry stain removal capacity when combined with commercial detergent. Also juice clarification assay showed promising results which indicates that the enzymes could be potentially used in detergent and food industry.
Prevalence Of Blood Groups And Association With Ailments In Pakistani Population: A Review of The Current Literature
Authors: Saadia Saad  , Syed Tousif Ahmed  , Ambrina Khatoon  , Jawaid Ansari  , Asaad J Mirza
Published: January 2023

The aim of this review is to report studies performed in Pakistan on the prevalence of blood groups among various sections of the population and their association with human diseases.  Google Scholar was searched for the last 20 years based on MESH keywords mentioned below. The inclusion criteria were the studies published in the new millennium that reported either prevalence of blood groups or their association with diseases in the Pakistani population.
There were 50 studies in Pakistan which fulfill the inclusion criteria. Among them, twenty- six were from Punjab, seven were from Khyber Pakhtunkhwa (KpK), six from Sindh, four from Kashmir, two from Northern areas, one from Baluchistan and 4 are review articles. This review concludes that blood group B is prevalent among Pakistani population followed by O, A and AB. Studies done in Azad Jammu Kashmir (AJK) and Gilgit- Baltistan reveal that B and A is prevalent in these areas respectively. AB is the least found group and Rh+ve is common among all studies. Moreover, this review also shows that blood groups act as a risk factor for many diseases. Therefore, Pakistani researchers are suggested to work on the genetic makeup of these blood groups to find out the cause of association with systemic ailments in the country.
Negative Air Environment-Induced Rehabilitation of Spasticity And Behavior During Physiotherapy in Cerebral Palsy Patients
Authors: Rafique Ammara , Naz Hajra
Published: January 2023

Introduction: Negative air ions (NAIs) are beneficial in improving memory, anti-depressant effects, productivity, psychological health, and well-being by inducing alkalinity in the body. Cerebral Palsy (CP) is a neurological disorder that impairs movement and elicits behavioral issues like anxiety, anger, agitation, dependency on others, hyperactivity, incompatibility, and stubbornness. Such behaviors may hamper their cooperation or willingness for physiotherapy. Methodology: Evidence-based studies to support that NAIs can augment the rehabilitation of CP are scant so, the present study was designed to determine if exposure to NAIs can normalize behaviors and physical outcomes. Ethical approval was taken from IBC, University of Karachi followed by the consent of the participants and the Al Umeed Rehabilitation Association where the intervention study was conducted in 2021. CP-inflicted participants were randomly allocated to the control and intervention groups. Both groups continued their regular twice-a-week physiotherapy sessions, but the intervention group also received 40-minute exposure to 10000 negative ions/cm3 for 6 weeks. Outcomes were assessed using a researcher-designed physiotherapist reporting questionnaire and Modified Ashworth Scale. Results: Analysis using SPSS v.28 demonstrated significant improvement in calmness, cooperation, physical condition, and willingness for physiotherapy along with minimal alleviation of spasticity. The possible role of neuronal pathways, synaptic response, and neurotransmitters such as acetylcholine, dopamine, gamma-aminobutyric acid, and serotonin have been discussed. Conclusion: The study concludes that NAIs may alleviate spasticity and normalize behaviors during physiotherapy sessions. We suggest the inclusion of this novel intervention in the multidisciplinary rehabilitation plan after going through the second and third-phase clinical trials.
Essay on Internal Threats to Democracy
Authors: Oikonomou Dimitrios Georgios
Published: January 2023

The article calls for a more crit­ical and also louder voice from contemporary political philosophy to respond to the major crises of the time. The argument is made that the most disconcerting and fundamental threat to de­mocracy is the inordinate amount of power held by big globalized capital, which deprives the peoples of modern states from any say in deciding economic policy in any meaningful way, and thus from a very important lever in steering our common life and controlling our common fortune. Political philosophy must rise to the task of reconnecting with current affairs and situations, of offering concrete solutions to concrete problems, of changing its outlook to in­clude interdisciplinarity and critique.
Free Speech & the Postmodern Town Square _ A plea for digital literacy
Authors: Dempf Sebastian
Published: January 2023

The article discusses restriction of free speech and opinions in times of digital media and the imperative for more digital literacy. In conclusion, the author argues that digital platforms' responsibility in governing town squares plays an important but not absolute role. Market incentives and challenges inherent to the nature of free speech make even well-intended content policies fallible. A new approach will therefore need to place greater focus on equipping end users with the tools necessary to critically engage in our digital economies to avoid their opinions becoming in­voluntarily skewed over the course of their town square visits.
Ішемічна хвороба серця та коморбідні захворювання у військовослужбовців (за матеріалами військово-лікарської комісії)
Authors: Moroz G. Z. , Ogorodniychuk I. V. , Bychkova S. A. , Romanenko V. S.
Published: January 2023

Мета. Провести комплексний аналіз поширеності коморбідної патології у військовослужбовців, хворих на ішемічну хворобу серця (ІХС), які були направлені на військово-лікарську комісію (ВЛК) для визначення придатності до військової служби за медичними показами. 

Матеріали та методи. Проведено аналіз медичної документації  84 військовослужбовців, які були направлені на ВЛК з діагнозом ІХС в 2018-2021 рр. для визначення придатності до військової служби за медичними показами. Всі хворі були чоловічої статі, вік від 34-х до 55-ти років. Для дослідження вікових особливостей перебігу ІХС та поширеності коморбідної патології військовослужбовці були розділені на дві групи: І група – до 45 років (35 військовослужбовців) – молодий вік; ІІ група – 46-55 років (49 осіб) – середній вік. Статистична обробка проводилась з використанням програми Microsoft Excel 2007 та стандартного статистичного пакета STATISTICA 6,0.

Результати. Встановлено, що військовослужбовці, хворі на ІХС, які були оглянуті ВЛК в 2018-2021 рр, мали ускладнений перебіг захворювання, зокрема, і в віковій групі до 45 років (у 100 % діагностовано серцеву недостатність, 17,1±6,4 % перенесли інфаркт міокарда, у 14,3±5,9 % проведено черезшкірне коронарне втручання та у 8,6±4,7 % аортокоронарне шунтування). Визначено значне поширення коморбідної патології у військовослужбовців, хворих на ІХС (кількість супутніх захворювань була від 3 до 9; в середньому – 7,3). Найбільш поширені коморбідні захворювання: артеріальна гіпертензія (100%), цереброваскулярні захворювання у 74,3±7,4 % хворих 1 групи та у 87,8±4,7 % ІІ групи (р > 0,05), остеохондроз хребта (65,71±7,1 % та 65,3±6,6 %, відповідно, р > 0,05) та хронічний гастродуоденіт (42,8±8,4 % та 40,8±7,0 %, р > 0,05). Потребує на увагу значне поширення ожиріння (31,4±7,8 % в І групі та у 40,8±7,0 % в ІІ групі) та цукрового діабету (22,9±7,0 % та 30,6±6,5 %, відповідно). Не визначено статично достовірних відмінностей щодо поширення коморбідної патології у військовослужбовців, хворих на ІХС, у віковій групі до 45 років (молодий вік) та 46-55 років (середній вік).

Висновки. Результати проведеного дослідження засвідчили, що військовослужбовці, хворі на ІХС, які були оглянуті ВЛК в 2018-2021 рр., мали ускладнений перебіг, значне поширення коморбідної патології (в середньому – 7,3 захворювань), що має негативних вплив на прогноз та обґрунтовує необхідність удосконалення первинної та вторинної профілактики з використанням підходів  пацієнт-орієнтованої медичної допомоги.
Методика оцінювання ймовірного ризику втрати здоров’я особового складу в умовах зараження небезпечними хімічними речовинами
Authors: Nikitin А. А. , Blekot О. М. , Romaniuk V. P. , Bevziuk A. P.
Published: January 2023

Мета роботи: висвітлення та обговорення існуючої методики оцінювання ймовірного ризику втрати здоров’я особового складу в умовах зараження небезпечними хімічними речовинами.

Матеріали та методи. В статті використані методи теорії управління та теорії ризиків.

Результати. Аналіз останніх досліджень і публікацій показав, що питанню підвищення ефективності функціонування військових підрозділів в умовах зараження небезпечними хімічними речовинами присвячений ряд наукових робіт в яких проведено ряд важливих досліджень. Але розглянуті підходи не враховують ризик втрати здоров’я особового складу військ (сил) та зниження їх боєздатності в умовах зараження небезпечними хімічними речовинами. У статті розглянуто методику оцінки ймовірного ризику втрати здоров’я особового складу в умовах зараження небезпечними хімічними речовинами, яка враховує ймовірність зараження особового складу небезпечними хімічними речовинами та уразливість до втрати його життя і здоров’я.

Висновки. Використання зазначеної методики дозволить автоматизувати процес оперативного планування під час фази оцінки обстановки та формування вихідних даних для планування, що дозволить здійснити оптимальний розподіл сил і засобів з урахуванням ймовірного ризику втрати здоров’я особового складу внаслідок зараження небезпечними хімічними речовинами. Також це дозволить зменшити ймовірність зараження військових об’єктів небезпечними хімічними речовинами що в свою чергу мінімізує уразливість особового складу оперативного угруповання військ та зменшить втрати здоров’я внаслідок зараження небезпечними хімічними речовинами в операційному районі.
Використання параметрів розчинності за Хансеном як методу прескрінінгу при розробці складу лікарських форм
Authors: Kolisnyk T. Ye. , Ruban О. А. , Mohylyuk V. V.
Published: January 2023

Вступ. Параметри розчинності за Хансеном (δd, δp, δh) дозволяють спрогнозувати ймовірність розчинності фармацевтичних інгредієнтів один в одному, а відтак науково-обґрунтовано звузити коло об’єктів та загальний обсяг експериментальних досліджень. Одним із способів визначення δd, δp, δh є розрахунковий метод групових внесків: усі три параметри розраховують, виходячи із внесків у відповідні міжмолекулярні взаємодії структурних груп, що складають молекулу речовини. Чим ближчими для двох речовин є параметри розчинності, тим з більш високою ймовірністю вони є розчинними одна в одній.

Мета дослідження – порівняння прогнозованої розчинності лікарських речовин згідно з розра­хованими параметрами розчинності за Хансеном з раніше опублікованими експериментальними даними для ілюстрації можливостей використання методу як прескрінінгу при розробці складу лікарських форм.

Матеріали та методи. Параметри розчинності за Хансеном визначено методом групових внесків за Ван Кревеленом і Хофтизером з використанням молярних об’ємів відповідних структурних груп за Федорсом для таких лікарських та допоміжних речовин: німесулід, мелоксикам, гліцерол, етиленгліколь, пропіленгліколь, поліетиленоксид (ПЕО) 400.

Результати дослідження. Відповідно до розрахунків, найкращим розчинником як для німесуліду, так і мелоксикаму є ПЕО 400. Користуючись критерієм Δδ ≤ 5 МПа0,5, німесулід є ймовірно розчинним лише у ПЕО 400, у той час як мелоксикам ймовірно не розчиняється в жодному з розчинників. Для кожного з зазначених АФІ ранжування за Δδ співпадає із експериментальним рядом розчинності у цих самих розчинниках. На підставі розрахованих даних відмічено, що з обраних допоміжних речовин саме ПЕО 400 за своїм молекулярним внеском у енергію водневих зв’язків найбільш наближений до обох АФІ.

Висновки. Параметри розчинності за Хансеном, визначені розрахунковим методом групових внесків за Ван Кревеленом і Хофтизером, дозволяють науково-обґрунтовано відібрати перспективні допоміжні речовини на етапі планування досліджень з розробки складу різних лікарських форм.
Neurorehabilitation in time of COVID 19: a perspective from Pakistan
Authors: Babur Muhammad Naveed , Muhammad Ehab Azim
Published: January 2023

A global public health emergency, the coronovirus disease-2019 pandemic has impacted every way of life, including neuro-rehabilitation, worldwide. Issues related to increased service demand in primary care, exhausted or insufficient healthcare facilities were significantly high in low and middle-income countries, like Pakistan, with already a struggling health infrastructure. This required major change in health service delivery and impacted rehabilitation care of vulnerable patients with neurological conditions and impairments. For the current review, relevant key words and their combinations were used for literature search, including ‘COVID 19’, ‘SARS-CoV-2’, ‘Corona Virus’, ‘rehabilitation’, ‘physical rehabilitation’, ‘pandemic’, ‘NCOC’, ‘lockdown’, ‘health services’, ‘physical therapy’, ‘disability’, ‘access’, ‘tele-rehabilitation’, ‘research’, ‘human resource’, ‘healthcare’, etc. The platforms searched were Google search, Google Scholar and PubMed. The idea was to highlight how the pandemic impacted neuro-rehabilitation care in countries like Pakistan throughout the pandemic duration and during the lockdowns.
Key Words: COVID 19, Disability, Health services, Neuro rehabilitation, Pakistan.
Issues of the 2024 Presidential Candidates in Online News Texts: Critical Discourse Analysis of the Teun A Van Dijk Model
Authors: Surya R Yusran , Jufri Jufri , Usman Usman
Published: January 2023

The discourse on the 2024 presidential candidate issue is a discourse formed by the practice of power which implies certain goals. Therefore, media discourse that reports on the 2024 presidential candidate issue is an issue or problem that contains critical languages or expressions. This research is important to find out the purpose or intention of the presidential candidate issue which reports on popular figures who have a major influence on social change and the progress of the country in the future. The purpose of this study is to analyze news texts about presidential candidates using the text dimensions of the Teun A. van Dijk model in the form of macro structure, super structure, and micro structure which are modified with the Jufri model. The type of method used is qualitative with a qualitative descriptive design that describes aspects of the text dimensions of the discourse structure, the data used is written text on the online news media CNN Indonesia, Jawapos.com, and Kompas.com. The results of this study are to describe the description and interpretation of the aspects of text dimensions in the form of macro structure, super structure, and micro structure which are then explained in the form of actions or actions that have a specific purpose. This research is useful for making a theoretical contribution and providing a conceptual overview that can inspire researchers or students who focus on the study of critical discourse analysis and can be implemented in critical discourse courses.
Web-Based Caricature Sales Information System Using the FAST Method
Authors: Siregar Nabilah Dewani Adha , Elsera Marina , Hadinata Edrian
Published: January 2023

The use of information technology has become widespread throughout all sectors of society, including government, business, healthcare, and education. Dalis Art Medan is a digital art-focused online store that opened its doors in 2017. Dalis Art's current sales system still relies on Facebook and Instagram because it does not yet have e-commerce, which results in low sales. Reporting mistakes are common since Dalis Art sales transaction data is still manually entered. E-commerce has been suggested as a solution to Dalis Art's issue with developing its sales operation. The FAST (Framework for the Application of Systems Thinking) methodology is used in this study. The FAST technique incorporates system users more actively in each stage of system development, is more adaptable, can be produced with other methods, and can be customized to the author's standard demands. The goal of this study is to make it easier for customers to learn about and purchase products from Dalis Art. Benefits might give consumers quick access to information on the items in Dalis Art. The study's findings demonstrate how fast and accurately a web-based sales information system, including details on products, ordering procedures, and payments, can be accessible via this method.
A Short Note on Numbers of the Form K + Fn, Where K ? {2, 4, 8} and Fn is a Fermat Number
Authors: Annouk Ikorong , Archambault Paul
Published: January 2023

A Fermat number is a number of the form , where n is an integer 0. A Fermat composite (see Dickson [1] or Hardy and Wright [2] or Ikorong [3]) is a non-prime Fermat number and a Fermat prime is a prime Fermat number. Fermat composites and Fermat primes are char­acterized via divisibility in Ikorong [3] and in Ikorong [4]. It is known (see Ikorong [3]) that for every j ∈ {0, 1, 2, 3, 4}, Fj is a Fermat prime and it is also known (see Hardy and Wright [2] or Paul [5]) that F5 and F6 are Fermat composites 641×6700417, and since 2013, it is known that +1 is Fermat composite number). In this paper, we show [via elementary arithmetic congruences] the following Result (E.). For every integer n > 0 such that n ≡ 1 mod [2], we have Fn−1 ≡ 4 mod [7]; and for every integer n ≥ 2, we have Fn−1 ≡ 1 mod[j], where j ∈ {3, 5}. Result (E.) immediately implies that there are infinitely many composite numbers of the form 2 + Fn. Result (E.) also implies that the only prime of the form 4 + Fn is 7 and the only primes of the form 8+ Fn are twin primes 11 and 13. That being said, using result (E.) and a special case of a Theorem of Dirichlet on arithmetic progression, we conjecture that there are infinitely many primes of the form 2+Fn.
Hybrid surgery for thoracoabdominal aortic aneurysm at Dong Nai General Hospital: A case report
Authors: Anh Vo Tuan , Tien Nguyen Cong , Son Kieu Minh , Dinh Nguyen Van , Anh Pham Minh , Phuoc Dang Ha Huu
Published: January 2023

Introduction: Thoracic and abdominal aortic disease is a rare, serious disease and one of the major challenges for the surgeon with a high prognosis of complications and mortality. Surgery combined with endovascular intervention is a new, minimally invasive method with good early results and good mid-term results.

Methods: We report a case diagnosed with thoracoabdominal aortic aneurysm underwent hybrid intervention at Dong Nai General Hospital

Results: A 68-year-old female patient was diagnosed with Crawford Type V thoracoabdominal aortic aneurysm, underwent debranching surgery of the superior mesenteric artery and celiac trunk followed by stent graft deployment of the diseased aorta, the postoperative course was uneventful.

Conclusions:  Hybrid surgery to treat thoracoabdominal aortic aneurysms can initially be performed at Dong Nai General Hospital. The implementation of this technique at provincial hospitals helps to improve prognosis, reduce mortality and complications, and contribute to improving the professional quality of the hospital.
Feasibility and accuracy of artificial intelligence for automatic qualification of two-dimensional and three-dimensional left ventricular ejection fraction and global longitudinal strain in echocardiography
Authors: Hoai Nguyen Thi Thu , Thom Vu Thi
Published: January 2023

To investigate if fully automated measurements of two-dimensional (2D) and three dimensional (3D) echocardiographic left ventricular ejection fraction (EF) and 2D global longitudinal strain (GLS) using a novel technology based on machine learning, deep learning and artificial intelligence (AI) are feasible and comparable with a conventional application by echocardiography cardiologists. Methods: From 12/2020 to 12/2021, 208 patients with heart disease with a wide range of EF were enrolled in the study in Vietnam National Heart Institute, Bach Mai hospital. Three standard apical cine-loops were analyzed using the AI model. The AI automated method measured 2D EF, 3D EF and GLS and was compared with conventional methods performed by echocardiography cardiologists. Results: The AI method succeeded to both correctly classify all three standard apical views in 95% of patients (four-chamber view: 94,2%; two-champer view:94,7% và three-chamber view: 95,2%.) and perform precise timing of cardiac events. There were strong correlations between 2D/3D EF measured by AI and the 2D/3D EF measured by echocardiography cardiologists (r = 0,78, p<0,001 and r = 0,65, p<0,001, respectively). There was a strong correlation between GLS measured by AI and the GLS measured by echocardiography cardiologists on speckle tracking echocardiography (r = 0,71, p< 0,001). Conclusion: Fully automated measurements of 2D/3D left ventricular ejection fraction and global longitudinal strain using a novel machine learning, deep learning AI-based technology are feasible and fast and they yield results comparable with conventional methods performed by echocardiography cardiologists.
Influence of Sitophilus oryzae on biological properties of Mycobacterium bovis
Authors: Zazharskyi Volodymyr , Alifonova Kira , Bilan Maryna , Kozak Natalia , Kasianenko Oksana
Published: January 2023

The active spread of tuberculosis around the world has been an urgent issue for many decades, but even now, there is no data on all available methods of introducing the pathogen into a previously healthy territory and the mechanisms of mycobacteria activity, and this makes it impossible to eradicate the disease completely. The purpose of this study was to determine the effect of the rice weevil (lat. Sitophilus oryzae) on the dissociative forms of mycobacterium tuberculosis, their viability, biochemical properties and virulence through passage of the pathogen through the insect’s body. To fulfil this purpose, the following methods were used: biological (experimental infection of laboratory animals), anatomical pathology and determining the viability of mycobacteria by counting colony-forming units. The effect on pathogenic properties of dissociative forms of Mycobacterium bovis (passage 118) after passage through the body of the rice weevil in an experiment on guinea pigs was determined and summarized. The change in the viability of mycobacteria isolated in the dynamics of the experiment in comparison with the original culture was described. The plasticity of the biochemical activity of the pathogen after passing through the body of the beetle was proven, and the influence of the macroorganism on the enzymatic properties of mycobacterium tuberculosis was analysed. The phenomena of the activation of enzymatic systems, which are associated with the adaptation and survival of mycobacteria in the conditions of a changed habitat, were substantiated. The practical value of this study lies in the improved understanding of the processes of the spread of mycobacterium tuberculosis and the established role of insects in the transmission of infection, with the prospect of developing measures to prevent and combat the disease
Identification of the bioaerosol microbiota in veterinary clinics as the key to preventing nosocomial infection
Authors: Mocherniuk Mykhailo , Kukhtyn Mykola , Horiuk Yulia , Savchuk Liubov , Mizyk Volodymyr
Published: January 2023

Nosocomial infections are important in veterinary medicine clinics, as they can contaminate surfaces and infect animals through bioaerosol and are the cause of ineffective antibiotic therapy. This paper presents a study of the effect of disinfection on the microbiota of bioaerozoic veterinary clinics. The purpose of this study was to establish the composition of the bioaerosol microbiota in veterinary clinic premises before and after disinfection with ultraviolet bactericidal lamps. Bioaerosol samples were taken in the premises of veterinary clinics by sedimentation method. Identification of the isolated microbiota was performed using classical methods involving commercial test systems for identifying microorganisms. It was established that the permanent microbiota of the bioaerosol of veterinary clinics includes the following representatives of gram-positive genera: Staphylococcus (coagulase-negative species), Streptococcus spp., Micrococcus spp., and Corynebacterium spp. These bacterial genera were present in the bioaerosol of all rooms in 100% of cases. Gram-negative species of bacteria were found in small quantities in the bioaerosol of such rooms as for the primary examination and the manipulation area with boxes for keeping sick animals. Representatives of gram-negative species were detected in a considerably larger number from the bioaerosol of the dental operating room during the day of the clinic. After disinfection with bactericidal lamps, pathogens of nosocomial infections (S. aureus, S. pseudintermedius, Acinetobacter baumani, P. aeruginosa) were released in the bioaerosol of such rooms as the primary examination, the manipulation area with boxes for keeping sick animals, and the dental operating room. This indicates that bioaerosol can serve as a medium for the spread of nosocomial infections among animals in veterinary clinics. Thus, conducting microbiological monitoring of bioaerosol in veterinary clinics will allow identifying pathogens of nosocomial infections and introducing preventive measures for the spread of pathogens
Efficiency of the sowing date of spinach in the southern steppe conditions of Ukraine
Authors: Ulianich Olena , Fedorenko Vitaliy , Ryabovol Liudmila , Shevchuk Kostiantyn , Voievoda Liliia
Published: January 2023

The population of Ukraine should receive fresh greens from early spring to autumn from open field production and the period of growing spinach will ensure the supply of fresh greens. The purpose of the research was to study the possibility of extending the period of fresh greens supplying from the open field due to the extension of the seed sowing period in the open field. The research was conducted in 2019-2021 in the conditions of the Southern Steppe of Ukraine. For the research, field, statistical, calculationanalytical and laboratory methods were used. The varieties Fantaziia and Malakhit were studied. The behaviour of plants after six sowing dates was examined. The control variant was the variety Fantaziia for sowing in the 1st decade of April. It was found that plants of both varieties of spinach had a larger leaf surface (114.2-127.7 cm2 ) in the early sowing period. Plants which were sown in August had a smaller leaf surface – 86.0-106.2 cm2 . The highest yield of marketable green mass was obtained for sowing in the 3rd decade of April and 2nd decade of May. The variety Fantasia provided 22.9-23.0 t/ha, and the variety Malakhit provided 23.3-23.9 t/ha. The sowing date had a significant influence on the main chemical parameters of spinach of the Fantaziia and Malakhit varieties. The higher indicators were the sowing dates in the third decade of April and the second decade of May, when the brix reached the level of 6.4-6.8%, the sugars content – 2.3-2.4% and the content of vitamin C – 58-70 mg/100 g. It was established that the soil and climatic conditions of the Southern Steppe of Ukraine were suitable for sowing spinach in six dates and would ensure an uninterrupted supply of products from the 3rd decade of April to the end of September inclusive, and in years with favourable weather conditions in the 2nd to 3rd decades September to mid-October. Such approach will solve the problem of seasonality in the consumption of fresh vegetables. The sowing dates are recommended to agricultural producers of spinach in order to extend the period of receiving fresh greens from the 3rd decade of April to the end of September and in some years to the middle of October
Technological and nutritional benefits of amaranth groats in breadmaking
Authors: Mykolenko Svitlana , Aliieva Olha , Aliiev Elchyn , Pivovarov Oleksandr
Published: January 2023

To increase the nutritional value of wheat bread as a staple food using non-conventional wholesome floury ingredients should meet high expectations of consumers. The study was aimed to investigate the effect of amaranth groats application into breadmaking focused on the technological qualities and biological value of wheat bread enriched with onion powder and safflower oil. The influence of scalded amaranth groats on the bread quality was measured by technological, physical, chemical, instrumental, and computational methods analysing raw materials and developed products. The use of the amaranth grain-derived ingredient at 4-8% as a valuable plant source in the wheat bread formulations enhanced the product consumer characteristics. The proofing of dough of the developed formulations was intensified followed by 6-20% increase in the bread specific volume and better organoleptic properties of bread. Amaranth groats showed high amino acid score for lysine (156%), phenylalanine and tyrosine (125%), and scores for threonine, valine, and cysteine were 2-fold to wheat flour scarce in bioactive compounds. The developed wheat-amaranth bread had an improved amino acid composition due to an increase in the number of essential amino acids, a 2.6 times higher protein utility, contributing to its digestibility. The main factor in changing the fatty acid composition of the developed products was the introduction of safflower oil with a high content of linoleic acid into the product. Introduction of scalded amaranth groats into bread formulations with vegetable-based additives is promising way to attribute the product with therapeutic, and health-improving properties
Impact of munitions corrosion processes on groundwater contamination and techniques for their safe and cost-effective disposal: A case study of a village
Authors: Semenenko Oleh , Trehubenko Stanislav , Onofriichuk Petro , Shyhyda Andrii , Remez Volodymyr
Published: January 2023

The relevance of the study lies in the fact that the ammunition that has entered the groundwater (deeper than 250 m), as a result of its disposal, poses serious threats to the entire Donetsk region water area. The purpose of the study was to investigate the impact of munitions corrosion on the aquatic environment and to consider the most effective and environmentally friendly methods of disposal. To conduct the research following scientific methods were used: methods of analysis, deduction, synthesis, and formalization method. It was found that each method of ammunition disposal led to a negative impact on the environment both in the short and long term. The literature of recent developments in munitions corrosion and munitions recycling was analyzed. It was summarized that there was an urgent need to introduce a system for cleaning up contaminated territories, to take control over the implementation of legislative environmental standards, to use new biological methods for elimination of the consequences of the impact of ammunition on the ecosystem of the region, and to switch to more environmentally friendly types of weapons. The practical value of the article is in search of ways to prevent an environmental and humanitarian catastrophe in the war zone in the East of Ukraine
Handmade Paper from MUSA Accuminata (Banana) Stem
Authors: Ms. Akanksha Mote  , Mr. Aniket Gavade  , Mr. Santosh Bandgar  , Mr. Avinash Narute
Published: January 2023

Banana stem is readily collected from banana trees after collection of banana fruits. The stem is used as a waste product and used in domestic cooking purpose. It’s removed after cutting of banana stem in small pieces and again stem is blowing inside the digester at a high pressure and consecutive use of sodium hydroxide, sodium sulphide and sodium hypochlorite.( 1) The fiber is molten and making pulp. In recent history there’s decline of Indian Handmade Paper in import request due to increase of cost of traditionally used good quality raw material. The present paper covers the potential for availability of banana fibre and its morphological & chemical nature as well as the pulping technologies with enzymatic refining.( 2) Banana fibre is a natural fibre with high strength, which can be blended lightly with cotton fibre or synthetic fibre to produce compound material. In the fiber extraction process, a substantial measure of Lignocellulosic wastes are generated, disposal of which creates problem in the adjacent area. In this paper, extracted banana fiber( EBF) and waste banana fiber( WBF) were characterized in terms of chemical and morphological plots to assumed Banana is one of the most well- known and useful plants in the world. Almost all the parts of this manufactory, that are, fruit, leaves, flower bud, trunk, and pseudo-stem, can be used. This chapter deals with the fiber extracted from the pseudo-stem of the banana plant of the banana plant. This chapter deals with the fiber extracted from the pseudo-stem of the banana factory. It discusses the product of banana pseudo-stem fiber, which includes colony and harvesting; extraction of banana pseudo-stem fiber; retting; and degumming of the fiber. It also deals with the characteristics of the banana pseudo-stem fiber, similar as morphological, physical and mechanical, duration, degradability, thermal, chemical, and antibacterial properties(3). Several possible uses of this fiber are also mentioned, similar as the use of this fiber to fabricate rope, place mats, paper cardboard, string thread, tea bags, high- quality fabric materials, absorbent, polymer/ fiber composites,etc.( 4).
Drug Traceability in Healthcare Supply Chain using Blockchain: A Review
Authors: Prof. Pushpanjali Sajjanshetti  , Ms. Sakshi Dahake  , Ms. Sharayu Nalawade  , Ms. Priya Nigade  , Ms. Tanvi Shinde
Published: January 2023

The goal of a drug traceability system is to track or trace where a drug has been and where it has gone along the drug supply chain, which is critical for public drug security and pharmaceutical company business. Traditional centralized server-client technical solutions have failed to meet expectations in terms of data integrity, privacy, system resilience, and adaptability. For drug traceability, we've proposed a totally new blockchain system. This solution is more secure and scalable than other options currently available. Furthermore, the suggested system can prune its storage effectively, resulting in a robust and useable blockchain storage solution.
Development and Validation of R-hf Risk Score in Acute Heart Failure Patients in the Middle East
Authors: Rajan Rajesh , Al Jarallah Mohammed , Al-Zakwani Ibrahim , Dashti Raja , Sulaiman Kadhim , Panduranga Prashanth , Brady Peter A , Kobalava Zhanna
Published: January 2023

Objectives: The Rajan’s heart failure (R-hf) score was proposed to aid risk stratification in heart failure patients. The aim of this study was to validate R-hf risk score in patients with acute decompensated heart failure. Methods: R-hf risk score is derived from the product estimated glomerular filtration rate (mL/min), left ventricular ejection fraction (%), and hemoglobin levels (g/dL) divided by N-terminal pro-brain natriuretic peptide (pg/mL). This was a multinational, multicenter, prospective registry of heart failure from seven countries in the Middle East. Univariable and multivariable logistic regression was applied. Results: A total of 776 patients (mean age = 62.0±14.0 years, 62.4% males; mean left ventricular ejection fraction = 33.0±14.0%) were included. Of these, 459 (59.1%) presented with acute decompensated chronic heart failure. The R-hf risk score group (≤ 5) was marginally associated with a higher risk of all-cause cumulative mortality at three months (adjusted odds ratio (aOR) = 4.28; 95% CI: 0.90–20.30; p =0.067) and significantly at 12 months (aOR = 3.84; 95% CI: 1.23–12.00; p =0.021) when compared to those with the highest R score group (≥ 50). Conclusions: Lower R-hf risk scores are associated with increased risk of all-cause cumulative mortality at three and 12 months.
New-onset Seropositive Rheumatoid Arthritis Post-mRNA COVID-19 Vaccine: A Case Report
Authors: Almouslem Amanda , Al Lawati Talal , Al Shirawi Ali , Al Amri Usama
Published: January 2023

Growing evidence in the medical literature has linked the COVID-19 vaccine as a potential trigger for the development or exacerbation of various autoimmune rheumatic diseases. To the best of our knowledge, we report one of the first cases of seropositive rheumatoid arthritis diagnosed after the messenger RNA COVID-19 vaccine.
History of the Arabs
Authors: Philip Hitti
Published: January 2023

This authoritative study of the Arabians and the Arabic-speaking peoples is a work of great thoroughness and insight which contains much to satisfy general readers as well as scholars. Here is the story of the rise of Islam in the Middle Ages, its conquests, its empire, its time of greatness and of decay, unrolling one of the richest and most instructive panoramas in history. For this reissue of the tenth edition, Walid Khalidi gives a brief overview of the history and content of the book, and emphasises the vital importance of Philip K. Hitti's magisterial and scholarly work to on-going attempts to bridge the Arab/Western cultural divide.

This accessible text is ideal not only for undergraduate and postgraduate students of Arabic and Islamic studies, but also for the general reader and many scholars in various fields of history.

New to this Edition:

- Fully updated with the results of new research

- Contains a new Preface by a leading academic in the field, which highlights the importance of this book to past and present attempts to close the cultural gap between the Arab and Western worlds
European Union Enlargement
Authors: Negent Neill
Published: January 2023

Since its first enlargement in 1973, expansion has become a way of life for the EU. The current round of enlargement is, however, unprecedented in its scale, in the diversity of applicants, and in the impact on EU structures and policies. This major new text brings together specially commissioned chapters to provide a coherent and comprehensive assessment of the historical and theoretical context of enlargement and its implications for the identity, governance, economics, policies and international role of the EU.
The Psychology Thesis
Authors: Smyth Thomas R.
Published: January 2023

No abstract Information
Modern British History
Authors: Black Jeremy
Published: January 2023

Jeremy Black’s compelling text provides a thematic account of British history centering on the twentieth century. To the traditional, chronological account of historic events, Black adds long-range thematic chapters reflecting the full range of topics. These include political structures, ideologies, wars and international relations, economic history, social history as well as consumerism, media and mass communication. The coverage is further enlivened with exhibits providing supplementary background information on key personalities and pivotal events, and numerous illustrations.
The Practice of Residential Work
Authors: Clough Roger
Published: January 2023

This text sets residential life and work in the context of wider social systems, focusing on the function homes serve in looking after young people and adults who would struggle to live elsewhere. Roger Clough highlights what residential workers need to know and do in order that, together with residents, they organise systems and lifestyle to provide the best service. Good residential practice develops from theory and understanding: of people, structures, residential practice, research methods and findings, organisational and management theory, and, critically, ethics and values.
Urban Europe, 1100–1700
Authors: Nicholas David
Published: January 2023

Reflecting the vigour of both urban and medieval history, this timely textbook by a leading scholar of urban studies is a broadly interdisciplinary work that breaks new ground by emphasising the links between the late medieval and early modern cities.

Urban Europe, 1100-1700:

- Examines the common social, governmental, economic and intellectual roles played by most pre-modern cities

- Views cities as originating in local market relations, then expanding with the growing complexity of their functions into regional centres of culture, government and exchange

- Adopts an organic, evolutionary and environmental approach, particularly in its application of geographical systems to early urbanisation

- Makes extensive use of maps and original source material to illustrate aspects of the urban experience

David Nicholas' study will appeal to students and scholars of history, geography and urban studies. Sociologists and political economists will also value its demonstration of the continuing relevance of the thought of Max Weber, while urban planners will find its analysis of the rationality of pre-modern cities highly useful.
Decision-Making under Uncertainty
Authors: Biswas Tapan
Published: January 2023

This new text deals with topics that are at the core of microeconomic theory - the economics of uncertainty and the economics of games and decisions. It contains a chapter on non-expected utility theory and very up to date coverage of such topics as risk aversion, stochastic dominance and mean-variance utility theory as well as a number of chapters that discuss and illustrate the use of game theory in making decisions under uncertainty.
The Bloomsbury Handbook of Popular Music and Youth Culture
Authors: Bennett Andy
Published: January 2023

The Bloomsbury Handbook of Popular Music and Youth Culture provides a comprehensive and fully up-to-date overview of key themes and debates relating to the academic study of popular music and youth culture. While this is a highly popular and rapidly expanding field of research, there currently exists no single-source reference book for those interested in this topic. The handbook is comprised of 32 original chapters written by leading authors in the field of popular music and youth culture and covers a range of topics including: theory; method; historical perspectives; genre; audience; media; globalization; ageing and generation.
Pain and Politics in Postwar Feminist Art
Authors: Warriner Rachel
Published: January 2023

Between 1966 and 1976, American artist Nancy Spero completed some of her most aggressively political work. Made at a time when Spero was a key member of the anti-war and feminist arts-activism that burgeoned in the New York art world during the period, her works demonstrate a violent and bodily rejection of injustice.

Considering the ways in which anti-war and feminist art used emotion as a means to persuade and protest, Pain and Politics in Postwar Feminist Art examines the history of this crucial decade in American art politics through close attention to Spero’s practice. Situating her work amongst the activism that defined the era, this book examines the ways in which sensation and emotion became political weapons for a generation of artists seeking to oppose patriarchy and war.

Exemplary of the way in which artists were using metaphors of sensation and emotion in their work as part of the anti-Vietnam war and feminist art movements in the late 1960s and early 1970s, Spero’s practice acts as a model for representing how politics feels. By exploring Spero's political engagement anew, this book offer a profound recontextualization of the important contribution that Spero made to Feminist thought, politics and art in the US.

Between 1966 and 1976, American artist Nancy Spero completed some of her most aggressively political work. Made at a time when Spero was a key member of the anti-war and feminist arts-activism that burgeoned in the New York art world during the period, her works demonstrate a violent and bodily rejection of injustice. Essential to this was a focus on pain. From the War Series (1966–1970) through the Artaud Paintings (1970–71), Codex Artaud (1971–2), and Torture of Women (1974–6), pain, both internal and external, was imagined in multiple forms. With an evolving attention to social violence, alienation and physical suffering, pain became metaphoric of the experience of women living under patriarchy, an amorphous but still profoundly disabling sensation that attacks both body and mind. Exemplary of the way in which artists were using metaphors of sensation and emotion in their work as part of the anti-Vietnam war and feminist art movements in the late 1960s and early 1970s, Spero’s practice acts as a model of a practice that seeks to represent how politics feels.

Considering the ways in which anti-war and feminist art used emotion as a means to persuade and protest, Pain and Politics in Postwar Feminist Art: Activism in the Work of Nancy Spero examines the history of this crucial decade in American art politics through close attention to Spero’s practice. Situating her work amongst the activism that defined the era, this book examines the ways in which sensation and emotion became political weapons for a generation of artists seeking to oppose patriarchy and war.