bluuebunny/crossref_metadata_2025 huggingface dataset:
ELISE: A Reinforcement Learning Framework to Optimize the Sloftframe Size of the TSCH Protocol in IoT Networks
Authors: Jurado Lasso Fabian Fernando , Barzegaran Mohammadreza , Jurado Jesus Fabian , Fafoutis Xenofon
Published: June 2023

The Industrial Internet of Things (IIoT) is shaping the next generation of cyber-physical systems to improve the future industry for smart cities. It has created novel and essential applications that require specific network performance to enhance the quality of services. Since network performance requirements are application-oriented, it is of paramount importance to provide tailored solutions that seamlessly manage the network resources and orchestrate the network to satisfy user requirements. In this article, we propose ELISE, a Reinforcement Learning (RL) framework to optimize the slotframe size of the Time Slotted Channel Hopping (TSCH) protocol in IIoT networks while considering the user requirements. We primarily address the problem of designing a framework that self-adapts to the optimal slotframe length that best suits the user’s requirements. The framework takes care of all functionalities involved in the correct functioning of the network, while the RL agent instructs the framework with a set of actions to determine the optimal slotframe size each time the user requirements change. We evaluate the performance of ELISE through extensive analysis based on simulations and experimental evaluations on a testbed to demonstrate the efficiency of the proposed approach in adapting network resources at runtime to satisfy user requirements.
Determinants of Low Modern Contraceptive Prevalence in the Health District of Markala/ Case of the Community Health Center of Diamarabougou
Authors: D Kanthé, , Y Samaké, , O Koné. , D Fomba, , B Bagayoko, T. , M Kéita, , B Samaké, , S Kéita, , M Traoré, , T Dembélé, B. , S Dembélé, K.
Published: June 2023

The level of use of MCMs remains low in our country. The objective of this study was to analyze the factors associated with the low use of modern contraceptive methods in the Diamarabougou health area. It was a cross-sectional study with an analytical focus conducted among 150 PAFs selected through random sampling. The study established the following: -Modern contraceptive prevalence was 35%. -The majority of women knew about family planning (99%). -The main source of information was health personnel (34.7%). -The reasons for the low use of MCM were The low level of education of the woman and/or her spouse, the desire to have many children and the unfavorable opinion of the spouse. -Both men and women believe that lack of control over the menstrual cycle, jealousy, and lack of distraction are the reasons for many unplanned pregnancies; - The main disadvantage of contraception is infertility. -The main disadvantage of contraception is sterility. For the ATRs, contraception is an effective way to fight against maternal and infant mortality. They also believe that the use of contraception and the choice of a smaller family are also accompanied by significant economic and material advantages, as expenses related to health, education and family maintenance are reduced. Conclusion : The use of modern contraceptive methods remains low in the Diamarabougou health area. The correct information to women and the identification of associated factors: the low level of education of the woman and her spouse, the desire to have many children, insufficient discussion with the spouse and the lack of involvement of traditional birth attendants in family planning programs.
UJI AKTIVITAS ANTELMINTIK EKSTRAK ETANOL KULIT BATANG SENGKUANG Dracontomelon dao (Blume) Merr & Rofle TERHADAP CACING GELANG AYAM (Ascaridia galli) SECARA IN VITRO
Authors:   Akademi Farmasi Yarsi Pontianak, Inderiyani Inderiyani , Puspasari Heny , Architasari Risma Wahyu
Published: June 2023

Worms are diseases caused by worms that need serious treatment. Sengkuang Dracontomelon dao (Blume) Merr & Rofle has the potential as an alternative worm treatment because it contains secondary metabolites i.e. alkaloids, saponins, tannins, flavonoids and triterpenoids which have activity as anthelmintics. This study aims to determine the activity, LC50 and LT50 values ​​of sengkuang stem bark as an anthelmintic against Ascaridia galli in vitro. Sengkuang bark is processed into simplicia and then macerated using 96% ethanol as a solvent. Then the extract was used to test the anthelmintic activity by incorporating 5 chicken roundworms into each test solution, 0,9% NaCl (negative control), 0,5% mebendazole (positive control), ethanol extract of sengkuang stem bark 0,2%; 0,4%, and 0,6%. Incubated at 37°C and observed the time of paralysis, the time and number of worm deaths every 1 hour for 24 hours. The results showed that the ethanol extract of sengkuang bark at concentrations of 0,2%; 0,4% and 0,6% had anthelmintic activity with a mortality rate of 100%, an LC50 value is 0,13% and an LT50 value respectively is 15,67 hours; 10,83 hours and 7,85 hours.
The use of dapaglifl ozin in a comorbid patient: new perspectives
Authors: Panevin T. S. , Eliseev M. S. , Bobkova A. O. , Dimitreva A. E. , Urumova M. M.
Published: June 2023

The development of the modern world is manifested, inter alia, by an increase in the prevalence of obesity and cardiovascular diseases. Treatment of these conditions is associated with the need to prescribe multicomponent therapy, which complicates the control of drug interactions, leads to a decrease in compliance and polypharmacy. A large number of drugs taken in a particular patient dictates the need to search for drugs, the appointment of which contributes to the control of several diseases at once, can be successfully used in patients with reduced renal function, in the presence of cardiovascular diseases. The presented description of a clinical case demonstrates an example of the use of a type 2 sodium glucose cotransporter inhibitor – dapagliflozin in a patient with type 2 diabetes mellitus, chronic kidney disease, chronic heart failure and gout.
Nervous system and kidneys. Cross-mechanisms of interaction in normal and pathological conditions
Authors: Yusupov F. A. , Yuldashev A. A.
Published: June 2023

In physiological states, the nervous system and kidneys interact with each other to maintain normal homeostasis in the body. However, pathological conditions such as hypertension, pathology of the kidney itself, both acute and chronic, disrupt this interaction. In acute kidney injury (AKI of various etiologies) and chronic kidney disease (CKD), damaged kidneys can have a significant impact on the function of the central nervous system. CKD is an independent risk factor for the development of cerebrovascular diseases and cognitive impairment due to many factors, including the retention of uremic toxins and phosphates, have been proposed as CKD-specific factors responsible for structural and functional cerebral changes in patients with CKD, however, additional studies are needed to determine the exact pathogenesis. Our review is devoted to the interaction of the kidney and the nervous system in physiological conditions and pathophysiological conditions, we are trying to reveal in detail the mechanisms of dysfunction of the nervous system in kidney pathologies.
The role of uric acid in the development of infl ammation in kidney disease
Authors: Kunitskaya N. A. , Ariev A. L. , Kulaeva N. N.
Published: June 2023

Asymptomatic hyperuricemia is frequently seen in patients with kidney disease. A significant number of epidemiological studies suggest that elevated uric acid levels play a causal role in the development and progression of kidney disease. But whether hyperuricemia is simply the result of reduced renal excretion of uric acid or contributes to the progression of renal disease remains controversial. Over the past two decades, numerous experimental studies have expanded the knowledge of the biological effects of uric acid beyond its role in the development of gout. In particular, uric acid induces activation of the immune system and affects not only renal tissue cells but also endothelial cells.  All this has led to the presentation of uric acid as a potential and modifying risk factor for kidney disease. This review examines the effects of uric acid on the immune system and further on renal tissue during inflammation.
The concentration of interleukin-17 in the blood and urine of patients with chronic glomerulonephritis with nephrotic syndrome
Authors: Chemodanova D. A. , Vinogradov A. A. , Сao V. , Krasnova T. N. , Chebotareva N. V.
Published: June 2023

BACKGROUND. In the mechanisms of immune inflammation in chronic glomerulonephritis (CGN), activation of T-cells plays an important role. The role of Th1 and Th2 cells in the pathogenesis of some forms of CGN has been well studied, while the activation of Th17 cells in CGN has been only evaluated in isolated studies. THE AIM: to evaluate the value of determining the level of IL-17 in urine and blood serum in chronic glomerulonephritis.

PATIENTS AND METHODS. Adult patients with active CGN (N=40) were recruited aged from 18 to 75 years. Ten patients had focal segmental glomerulosclerosis, 6 had membranoproliferative glomerulonephritis, 15 had IgA nephropathy, and 9 had membranous nephropathy at histological examination. The control group included 10 healthy subjects. The IL-17A levels in the urine and blood serum were determined by enzyme-linked immunosorbent assay (ELISA). The IL17A levels in the urine were calculated as the ratio to urinary creatinine. The levels of IL-17 in urine and blood serum were compared with the indicators of proteinuria, albumin, creatinine, serum sodium, also the severity of hypertension, edema and daily sodium excretion.

RESULTS. The results of our study showed a significantly higher concentration of IL-17 in urine in patients with a marked decrease in renal function. Also, the levels of IL-17 in urine directly correlated with serum sodium and inversely correlated with eGFR. We also found an association between increase levels of IL-17 in urine with arterial hypertension and the severity of edema. There were no significant correlations of IL-17 in blood serum and other laboratory indicators of nephritis activity.

CONCLUSION. Patients with CGN have increase levels of IL-17 in the urine compared to healthy subjects. A more significant increase of IL-17 in urine is observed in patients with high clinical activity of HCG. IL-17A may participate in the mechanisms of sodium retention, the development of hypertension and edema in patients with nephrotic syndrome.
The structure of detected kidney diseases based on the results of forensic medical examination of corpses
Authors: Yagmurov O. D. , Isakov V. D.
Published: June 2023

The structure of the detected kidney pathology was studied according to the results of a forensic medical examination of corpses in the St. Petersburg Bureau of Forensic Medical Examination (BSME) in 2020–2021. As a result of the research, it turned out that out of the total number of all corpses that were sent by the investigative bodies for forensic medical examination to the St. Petersburg Bureau of Forensic Medical Examination over the years, kidney pathology amounted to 0.7 %. The most frequent (67 %) renal pathology leading to death were malignant kidney diseases. In the group of malignant kidney diseases, the age of the deceased was in the range of 40–90 years (with a pronounced peak of 80–90 years). The age of the majority of those who died from non-malignant kidney diseases was 50-90 years (with a pronounced peak of 80-90 years). Gender differences in the causes of death in the groups of malignant and non-malignant kidney diseases have not been established.
TRANSITION FROM OPEN PIT COAL MINE TO THE UNDERGROUND MINE IN SOFT ROCKS
Authors: Narmatov Akhror
Published: June 2023

To achieve a successful and effective operation, the transition from open pit to underground mining requires accurate planning and analysis. Numerical modeling utilizing programs like FLAC3D has been an important tool for simulating and analyzing the complicated geomechanical behavior connected with this shift in recent years. The use of FLAC3D to develop a model for the switch from open pit coal mining to underground coal mining in soft rocks with using room and pillar mining method is explored in this abstract. It presents the development of model to analyze and simulate the complex dynamics of this transition.
The significant considerations that went into developing the model, such as geotechnical characteristics, rock mass behavior, and mine design parameters, are highlighted in the abstract. It highlights how essential proper input data are to producing reliable simulations and forecasts in soft rocks. The usage of FLAC3D for tracking pit wall stability during the transition period, evaluating the influence on nearby infrastructure, and optimizing underground mine design are covered in the abstract. The models flexibility allows the investigation of various conditions and offers valuable insight about the transition process.
The research emphasizes the potential of the FLAC3D model to lead decision-making during the transition from open pit to underground mining through detailed analysis like choosing appropriate width for main entrance and cross section stopes and their interpretation. It emphasizes how important it is to understand the geomechanical behavior of the coal deposit, optimize the mines design parameters, and ensure safety for employees. The room and pillar method is utilized to recover coal resources from deep underground mines, and the results from the model can help improve efficiency, sustainability, and risk prevention.
KEYWORDS: Underground mining, Open pit mining, Room and Pillar mining method, FLAC3D, Coal mining, Soft rocks.
EXTRAFISCALIDAD DEL NUEVO RÉGIMEN SIMPLIFICADO DE CONFIANZA
Authors: Ojeda Pérez Fabián
Published: June 2023

El impuesto sobre la renta desempeña un papel importante dentro del sistema tributario mexicano, ya que es el tributo que mayor recauda en los ingresos tributarios de México. No obstante, dicho tributo también ha sido empleado como instrumento para el impulso de ciertos sectores económicos del país. De esta forma, en el presente estudio se analiza el Régimen Simplificado de Confianza de personas físicas a la luz de la extrafiscalidad de los tributos, a fin de explorar las características de su tratamiento fiscal y exponer porqué es un régimen extra fiscal. Es una investigación de tipo documental de carácter jurídico, en la cual se revisa la fuente jurídica de dicho régimen y la principal literatura sobre la extrafiscalidad. Dentro de los principales resultados, se describe al Régimen Simplificado de Confianza como extrafiscal ya que se orienta a incentivar a las personas físicas a cumplir con sus obligaciones fiscales.
Where We Rats Lurk
Authors: Ranjan Ram Krishna
Published: June 2023

This work has emerged as part of an ongoing doctoral research in artistic practice that aims to mobilize film practice to foreground subaltern experiences of the Bengal Famine of 1943. Mrinal Sen's Akaler Sandhaney is one of the most important films on the famine and the video work Where we rats lurk can be seen as a critical intervention in Sen's film. The video work is animated by the question - what are the limits of self-reflexivity in Mrinal Sen’s Akaler Sandhaney and can they be unsettled without undermining their critical potential in filmmaking practices?
Systematic Review: Analisis Hubungan Kualitas Tidur dengan Kelelahan Kerja pada Tenaga Kerja
Authors: Armadani Devina Farry , Paskarini Indriati
Published: June 2023

Seiring dengan perkembangan industri yang begitu pesat, waktu untuk melakukan aktivitas pekerjaan menjadi lebih panjang dan para pekerja dituntut untuk bekerja dengan hasil optimal. Jam kerja yang terlalu banyak dan berubah-ubah menyebabkan waktu istirahat dan tidur pekerja menjadi berkurang sehingga meningkatkan tingkat kelelahan saat bekerja. Penelitian ini dilakukan untuk mengetahui adanya hubungan antara kualitas tidur dengan kelelahan kerja pada tenaga kerja. Penelitian ini merupakan tinjauan pustaka sistematis dengan metode PRISMA (Preferred Reporting Items for Systematic Reviews and Meta Analyses). Pencarian literatur diperoleh dari Google Scholar, Science Direct, PubMed, Garuda Jurnal, dan Neliti Jurnal. Kata kunci "sleep quality AND work fatigue" dan "kualitas tidur AND kelelahan kerja" digunakan dalam artikel yang terbit dari tahun 2018-2023. Sebanyak 709 artikel ditemukan, namun hanya 8 artikel yang layak digunakan setelah melalui proses eliminasi yang disesuaikan dengan topik penelitian, lolos duplikasi, dan dapat diakses secara menyeluruh. Hasil menunjukkan bahwa terdapat hubungan yang signifikan antara kualitas tidur dengan kelelahan kerja serta penurunan kualitas tidur pada pekerja dikaitkan dengan peningkatan tingkat kelelahan kerja. Pengaturan waktu kerja dan istirahat yang buruk pada berbagai jenis pekerjaan, dapat berpengaruh terhadap kualitas tidur pekerjanya sehingga kualitas tidur yang baik diperlukan untuk menurunkan tingkat kelelahan kerja.
Hubungan Teknik Relaksasi Benson Terhadap Kadar Gula Darah Pasien Penderita Diabetes Militus Tipe 2
Authors: Zega Beni Wijaya , Sembiring Lora Pati Adelina Br , Laoli Delvin Sri Ariani , Silaban Helen Taruli T. , Ginting Chrismis Novalinda
Published: June 2023

Pasien diabetes militus sekelompok yang mengalami metabolisme yang dikenali dengan gula darah tinggi. Pasien yang memiliki diabetes mempunyai resiko dua kali lipat yang mengakibatkan terkena penyakit kardiovaskuler dan terdapat sekitar 75% diabetes akan mengakibatkan kematian. Maksud dari penelitian ini ialah untuk  memahami adakah pengaruh korelasi relaksasi benson dengan derajat kadar gula  darah pada pasien DM. Metode riset menggunakan metode Quasy experiment menggunakan desain pre test-post test design. Populasi digunakan pada riset ini yaitu seluruh pasien yang mengalami penyakit gula darah yang tinggi pada DM tipe 2  di puskesmas Darussalam dari bulan Juni-Desember 2022 dengan jumlah 56 responden. Penarikan sampel yang kami gunakan yaitu sampel random untuk menentukan banyak sampel yang akan diambil. Media ukur yang digunakan yaitu lembaran observasi. Dalam penelitian ini ada dua analisa data yang digunakan yaitu analisa univariat yang dimana hasilnya dimasukan dalam tabel distribusi frekuensi dan analisa bivariat dengan menghubungkan dua variabel dengan uji t berpasangan. Hasil penelitian Karakteristik pada penderita DM tipe 2 mayoritas pada jenis kelamin laki-laki, usia >66, pendidikan terakhir SMP dan status pekerjaan tidak bekerja. Kadar gula darah yang penderita DM terdapat tipe 2 sebelum dilakukan dan sesudah dilakukan relaksasi benson terhadap perbedaan.Ada hubungan teknik relaksasi benson terhadap gula darah pada penderita DM tipe 2.
Trauma Mata di Bidang Agrikultur
Authors: Afifaldo Berlyantama , Himayani Rani , Oktarlina Rasmi Zakiah
Published: June 2023

Indonesia merupakan negara agraris dengan sebagian besar penduduknya merupakan tenaga kerja pertanian. Menurut data Badan Pusat Statistik tahun 2021, Total jumlah tenaga kerja di bidang pertanian ini mencapai 26,03% dari jumlah tenaga kerja keseluruhan di Indonesia. Dari banyaknya tenaga kerja di bidang pertanian di Indonesia, maka adanya kemungkinan terjadinya trauma pada mata ketika sedang berkerja. Trauma mata merupakan penyebab tersering dari kehilangan penglihatan yang bersifat unilateral dan juga gangguan permanen. Tujuan dari penulisan artikel ini ialah agar dapat mengetahui tentang trauma mata di bidang agrikultural. Artikel ini ditulis menggunakan metode literature review yang dilakukan dengan literature searching dari berbagai jurnal baik nasional serta internasional dari tahun 2008 – 2021 dan dipilih 15 artikel. Penulis mendapatkan refrensi dari database NCBI, Pubmed, dan Google Scholar dengan kata kunci “trauma mata”, “agrikultur”, dan “pencegahan trauma mata”. Dari artikel yang telah didapatkan selanjutnya dilakukan analisis dengan metode systemic literature review meliputi kegiatan pengumpulan, evaluasi, dan pengembangan penelitian dengan fokus tertentu.
The Effectiveness of Swiss Ball Exercise to Increase Balance and Mobility of Patient with Stroke
Authors: Agina Widyaswara Suwaryo Putra , Santoso Eko Budi , Utoyo Bambang
Published: June 2023

Stroke cases increased to 10.9% in 2018 or an estimated 2.1 million people. Central Java was ranked in the top 10 with 11.8% of stroke cases. Post-stroke control adherence to health care facilities nationally is also still low. The development of treatment methods for stroke patients has been very rapid in hospitals, starting from therapy, rehabilitation care and the results have shown a decrease in mortality due to stroke in the acute phase. The most effective method to improve balance and mobility of post-stroke patients is using Swiss Ball Exercise. The purpose of this study was to prove the effectiveness of Swiss ball exercise on the level of balance and mobility in post-stroke patients. This study used a quasi-experimental design with a pretest-posttest control group design, with a post-stroke patient population. The sample in this study was taken by consecutive sampling technique, with the inclusion criteria of acute post-stroke patients who experienced pharese or weakness of the upper and lower limbs for a duration of 1-3 months, aged 40-60 years, male and female patients, no disturbances. visual and sensory disturbances. Exclusion criteria were patients with spinal deformity, mental disorders, a history of spinal surgery, hemorrhagic stroke and cognitive deficits. The research sample amounted to 36 people who were divided into 2 groups. The first group got Swiss Ball Exercise in 35-40 minutes for 6 days/week once a day for 3 weeks. The results showed that the control group and the intervention group were 18 respondents respectively. Swissball exercises were carried out by respondents with the assistance of a facilitator for 6 times in 1 week and were carried out for 3 weeks, a total of 18 times. The results of statistical tests using the Wilcoxon test showed that there were significant changes in stroke patients, the majority of whom had non-hemorrhagic strokes. These changes were assessed using the Berg Balance Scale (p=0.005) and the Time Up Go Test (p=0.002) in the intervention group. Conclusion that swiss ball exercise is effective to improve balance and mobility of post-stroke patients
Description of Cyberbullying Behavior in Adolescents
Authors: Fitria Yeni , Firnanda Dhea , Kurniyawan Enggal Hadi , Dewi Erti Ikhtiarini , Laras Ati Niken Asih
Published: June 2023

Emotional enhancement as one of the characteristics of adolescence development causes adolescents vulnerable to juvenile delinquency such as bullying. In the current era of technological development, bullying is not only done directly but can also be done through social media or cyberbullying. This study aims to describe cyberbullying behavior in adolescents at Jember High School. This study aims to describe cyberbullying behavior in adolescents at Jember High School. The research method used was descriptive quantitative with 319 students in a high school in Jember Regency as a sample. The sampling technique uses proportionate stratified random sampling. The measurement tool used is The Second Revision of the Revised Cyber Bullying Inventory-II (RCBI-II) which has been translated and modified. The results showed that 13.8% of students became perpetrators, 17.9% became victims, 37.6% became both perpetrators and victims, and 30.7% were not involved. The conclusion from this study is that there is a high level of cyberbullying behavior in adolescents. There needs to be follow-up from the school to provide moral education, especially about the negative effects of cyberbullying on adolescent mental health as an effort to prevent cyberbullying behavior in students. In addition, parental supervision is also needed on adolescent activities in social media to minimize adolescent involvement in cyberbullying.
The Indonesian Version of Sayles Internalized HIV Stigma Scale: Preliminary Test of Reliability
Authors: Raya Nyoman Agus Jagat , Sekar Sari Ni Made
Published: June 2023

The needs for an Indonesian version of a tool to measure internalized HIV stigma are identified. This study aims to evaluate the reliability of the Indonesian version of Sayles Internalized HIV Stigma Scale and the correlation of each subscale. A cross-sectional preliminary study involving purposively sampled 20 persons infected with HIV in Bali, Indonesia was conducted. The internal consistency reliability was examined through Cronbach’s α and item-total correlation. Meanwhile, the correlation of each subscale was examined by using Spearman’s Rank correlation coefficient. The results showed a Cronbach’s α of 0.924 and the item-total correlation range from 0.151 to 0.837. Significant positive correlation between overall scale and each subscale were confirmed. These findings indicated acceptable reliability of the Indonesian version of Sayles Internalized HIV Stigma Scale and the possibility of its use as an alternative to assess the internalized HIV stigma in Indonesia.
Ubah gulma menjadi emas: studi kasus pengolahan eceng gondok menjadi humus aktif & enzimatik di Waduk Jatiluhur Purwakarta
Authors: Poernama Teddy , Pebriansyah Eka , Arifin Antoni Ludfi , Yusuf Rully
Published: June 2023

Water hyacinth increase flourishingly and spread rapidly and it potentially harms aquatic ecosystems as it covers water surface and endanger water ecosystems. In Jatiluhur reservoir, the water hyacinth has spread up to 10% of the entire reservoir. Therefore, society's participation in developing active humus/compost and liquid fertilizer from water hyacinth is advantageous for Tirta Emas farmers group in Desa Jatimekar, Kecamatan Jatiluhur, Purwakarta. Furthermore, this study aimed to observe the involvement of PT Pegadaian in the goldifying water hyacinth collaboration program by KUBMN. This study was a literature research as the research was conducted by collecting numerous literature sources such as research articles, books and reports regarding goldifying weeds or water hyacinths and the role of PT. Pegadaian in the program. In the library research, the researchers collected more than 50 research articles, books and study reports regarding water hyacinth's benefits and it's economic potentials. Thus, this study identified that the goldifying program of PT Pegadaian was advantageous in some aspects such as: 1) Ecological aspects: Water environment in Jatiluhur reservoir was better. Because the negative impacts of water hyacinth could be decreased and it was more controllable. 2) Economic aspect: people's income increased as a result of liquid fertilizer from water hyacinth program and sustainable fish cultivation. 3). Social aspect: the beauty of nature in Jatiluhur reservoir without water hyacinth, the emergence of tourist attractions and a harmony relationship between PTJ II as reservoir's manager and people in society.
Chemical injury for a sexual attack on a minor person: the question of the amendment of other criminal legal measures
Authors: TAVOLZHANSKA Yuliia , ROMANOVA Viktoriia , SHULIAKA Yana
Published: June 2023

In connection with the increase in the number of cases of violent acts related to sexual crimes, some countries have adopted legislation that provides for the use of chemical castration as a criminal-legal measure of a medical nature. The positions of defenders and opponents of the use of this method are analyzed, and the effectiveness of chemical castration as a means of preventing repeated crimes is also investigated. This topic is relevant for justice, medicine and the public, as it concerns serious issues of human rights and the ethics of using medical methods for law enforcement purposes.
It can be argued that the introduction of chemical castration will be appropriate to counter the pandemic of sexual crimes against minors, but this issue has many acute angles. It is important not to level the voluntary nature of this procedure by depriving the person of the right to choose. The basis for castration must be a socially dangerous act, the harmful consequences of which must be commensurate with the interference with the normal reproductive activity of a person.
Some studies have shown that chemical castration can reduce the risk of repeat crimes related to sexual activity. However, other studies indicate that chemical castration is not a universal means of preventing recidivism, and its effectiveness depends on the specific situation.
New research also focuses on the ethical aspects of using chemical castration, including the issues of informed patient consent, possible side effects, and the duration of castration. In addition, it examines whether chemical castration can be used as an alternative to punishment, as is commonly done in criminal law situations.
In our opinion, chemical castration is an innovation in the criminal legal field of Ukraine. But it needs thorough discussion and testing in practice. We investigated the issue of sexual crimes against particularly vulnerable persons and followed the changes made to the criminal legislation of Ukraine in recent years.
Peculiarities of strategic management of risks of economic activity of enterprises in conditions of systemic crisis in Ukraine
Authors: MARTYNOVA Liliia , CHERNODUBOVA Eleonora
Published: June 2023

The role of risk as a base category in the enterprise management system is substantiated, which determines the possibility of losses and additional costs and, at the same time, is a necessary condition for profit. The essence and components of the process of economic risk management at the enterprise are investigated. It is determined that the process of economic risk management characterizes the combination of the following main components: identification and assessment of the level of risk; making management decisions and choosing risk management tools; implementation of adopted risk management decisions; control over the implementation of management decisions and assessment of their effectiveness.
The composition of internal regulatory documents that can be used to regulate economic relations in the field of risk management at the enterprise is determined. Principles and peculiarities of formation of risk management strategy at the enterprise in conditions of systemic financial and economic crisis are organized. It is substantiated that strategic risk management should be based on the principles: complexity, adaptability, analytics, economy and scientific substantiation.
The main stages of formation of strategy of management of risk of economic activity of enterprise are substantiated: identification and structuring of risks; analysis of the nature and characteristics of risk factors; assessment of the level of exposure to individual types of risk and determination of the overall level of risk; forecasting of losses of the enterprise as a result of occurrence of risk events by certain types of risks; making strategic decisions on risk management and developing a mechanism for practical implementation of the risk management strategy.
A model of the enterprise risk management process with a focus on the strategic component of management with an enhanced control and analytical component and an adaptive component has been developed.
Theoretical approaches to digital transformation in enterprise management
Authors: MYTROKHIN Leonid , IHNATIUK Viktoriia
Published: June 2023

The paper is devoted to the study of digital transformation in management. Currently, the problems of implementing an effective digital transformation at enterprises are becoming particularly relevant in the context of the fact that the transformation is one of the key factors in increasing the competitiveness of the organization. Due to the continuous development of technology and the growth of the digital economy, organizations are facing significant changes in the business environment. Digital transformation allows companies to adapt to these changes and use new opportunities to improve efficiency and productivity. The paper examines the definition of digitalization, explores the theoretical foundations of digital transformation in management; due to the significance of the transformation of the organization as the main factor in increasing competitiveness. Digital transformation in today's business environment has become a must for companies seeking to innovate and achieve competitive advantage. Due to the rapid development of technologies, management processes and methods are undergoing significant changes. Digital solutions allow you to automate business processes, simplify data collection and analysis, improve communication and collaboration between different departments and employees. This helps reduce routine work, increase productivity and focus on strategic planning and innovation. However, digital transformation also creates new challenges for management that require attention and solutions. The rapid development of the digital economy, the excessive level of changes in the external environment and market competition require enterprises to optimize and effectively build business processes, as well as focus on improving the competitive strategy.
Surmounting of the impediments on the way to Ukraine`s accession to the European Union
Authors: BREDUN Svitlana , PYTOMETS Anastasiia , BOLOTOV Oleksii
Published: June 2023

The paper highlights the topic of European integration. Ukraine has decided on the vector of foreign policy, setting the goal of integration into the European political, economic and legal space with the aim of gaining membership in the European Union. Namely, accession to the EU is a strong incentive for development and improvement of many aspects of the functioning of our state. In 2022, during an extremely challenging period for Ukraine, a qualitatively new stage of European integration began – Ukraine received the EU candidate status, which made the prospects of joining the European community feasible, became a catalyst for further reforms, and an incentive for the authorities and citizens of the country. The EU candidate status has opened up a number of vectors for our country to carry out reforms in various areas. These are primarily structural changes, shift away from the consumer economy model, improvement of production efficiency, expansion of access to new technologies, new investments, etc. This is the country`s achievement of a new level of development comparable to EU member states.
Six fundamental values of the European Union – supremacy of law, respect for human dignity, democracy, freedom, equality and respect for human rights – these are the most vital worldview principles, which are close and understandable to our society – to every Ukrainian. They exactly unite us with Europeans more than any laws or agreements. The EU enlargement process opens new strategic prospects for Ukraine and additional opportunities to deepen the European integration policy of our state. However, at the same time, at the current stage of Ukraine's relations with the European Union, there are many problems that must be eliminated, in order to become a member of the EU.
In this paper, we considered Ukraine's path to European integration, highlighting the opinions of political and public figures regarding the importance of our state for European space. It was noted which criteria for EU membership exist, it was also analyzed which of them Ukraine has already fulfilled. Attention was focused on the reforms that should be carried out in order to obtain EU membership. It was clarified what are the obstacles to the European integration of Ukraine and it was indicated the ways to overcome them.
Exchanges of visits of the Ministers of Fisheries of the USSR and Japan and a look at modern fishing Russian-Japanese relations from 2023
Authors: Kurmazov Aleksandr
Published: June 2023

After 1956, relations between the USSR and Japan in the field of fisheries began to develop rapidly. The ministers of fisheries of the two countries played a huge role in this process. During the existence of the USSR, an extensive legal base for such relations was formed. Modern fishing relations between Russia and Japan are regulated by a contractual basis, formed back in the Soviet period. The paper provides a detailed chronology of Soviet-Japanese fishing relations and the specific participation in this process of the Ministers of Fisheries of the USSR and Japan. An assessment is given of the current state of bilateral relations in the field of fisheries, which are mainly based on the legal legacy of the Soviet period. Painful points of relations, which also got from that time, are noted.
Commercial fishing of Pacific herring (Clupea pallasii) in January-April 2023 in the northern part of the Sea of Okhotsk
Authors: Smirnov Andrey , Semenov Yuri , Omelchenko Yuri , Burlak Philipp
Published: June 2023

Based on the materials collected in January-April 2023, the features of the fishing of the Okhotsk and Gizhiginsky-Kamchatka herring living in the northern part of the Sea of Okhotsk are considered. The areas of operation of vessels in the fishery are shown, the indicators of average catches of large and medium-tonnage vessels and the number of fishing vessels are given by month. Data on the average body length of herring, by-catches of pollock and juvenile herring are presented.
The current state of Japanese mackerel Scomber japonicus and the peculiarities of its nutrition in feeding areas
Authors: Kuznetsova Elena , Belorustseva Svetlana , Sogrina Anastasiya
Published: June 2023

During a period of high stock levels chub mackerel migrates to Russian waters for feeding and become available for domestic fisheries. In 2016, the domestic mackerel fishery was organized after a long break. Mackerel catches increased until 2018, followed by a slight decline. Based on the materials of the autumn survey conducted in Russian waters of the Northwest Pacific Ocean in 2020, the size and age composition, biological condition and nutrition of chub mackerel during feeding in the South Kuril zone is given.
ANALYSIS OF MORAL VALUES IN THE ENOLA HOLMES MOVIE
Authors: Kurniati Natalia Sri , Bunau Eusabinus , Rezeki Yanti Sri
Published: June 2023

The purpose of this research was to examine the kinds of moral values and describe how they are presented in the Enola Holmes movie directed by Harry Bradbeer. The research design was a descriptive qualitative study and the Enola Holmes movie script was the primary data source. The SPEAKING Model (setting, participants, ends, act sequence, key, instrumentalities, norms, genre) by Dell Hymes is used as the framework to assess the conversation in the movie. The results showed that the movie contained some moral values defined by Haidt such as care, fairness or proportionality, liberty, authority or respect, and loyalty or in group, also moral values defined by Barrow, such as fairness, respect for persons, freedom, and well-being. The most dominant  moral values in this movie were liberty or freedom. The moral values are stated mostly by the characters in the movie directly, while some are stated indirectly. The moral values described in this research have important implications for teachers and other researchers, which encourage the use of various tools in analyzing discourse in literary works and able to apply the moral values in daily life.Keywords: moral value, literature, SPEAKING model, descriptive.
EVALUASI PEMBELAJARAN APRESIASI SASTRA KELAS V.C SD NEGERI 21 TARAI BANGUN, KAMPAR: STUDI KASUS MEMBACA PUISI
Authors: Abidin Zainal
Published: June 2023

Penelitian ini bertujuan untuk mengidentifikasi kasus kesulitan pembelajaran membaca puisi siswa sekolah dasar. Penelitian ini merupakan penelitian studi kasus dengan data yang diperoleh dari subjek kasus guru dan siswa kelas V.C SDN 21 Tarai Bangun, Kampar. Data berupa perilaku kesulitan belajar diambil dengan teknik observasi, wawancara, dan dokumentasi. Langkah-langkah yang dilakukan meliputi identifikasi kasus, diagnosis, prognosis, remedial (treatment), evaluasi, dan tindak lanjut (follow up). Hasil penelitian menunjukkan bahwa penyebab kasus kesulitan pembelajaran apresiasi sastra, khususnya membaca puisi, adalah kondisi kelas dan faktor guru. Kondisi jendela kelas yang terlalu rendah dapat diatasi dengan memberi penutup berupa tirai untuk menghalangi pandangan siswa ke luar ruangan, sedangkan guru yang kurang menguasai kelas karena kekurangan media pembelajaran dapat diatasi dengan penyediaan buku penunjang lain selain buku utama, majalah, dan proyektor.Kata kunci: pembelajaran; apresiasi sastra; studi kasus; membaca puisi.
Icons and metaphors in visual communication: The relevance of Peirce’s theory of iconicity for the analysis of visual communication
Authors: Thellefsen Martin , Friedman Alon
Published: June 2023

In this paper we adopt Charles Sanders Peirce’s concept of iconicity to analyse pictural communication. While visual semiotics has a well-developed structural school, the concepts of visual semiotics stemming from Peirce’s pragmatic sign theory are often overlooked. The specific purpose of this study is to explore the semiotics of visual signs, exemplified by two prominent pictures of former US President Donald Trump. We argue that Peirce’s semiotic framework for iconicity in visual signs (the image, the diagram, and the metaphor) offers a useful framework for discussing how the meaning of visual signs is motivated. On this basis, we propose that Peirce’s concept of hypoicons provides us with a richer understanding of how visual signs acquire meaning and how their interpretation varies across cultural habits, and collateral experience.
Analisis Strategi Pengembangan Usaha Menggunakan SWOT dan Business Model Canvas Pada Produk Air Minum Dalam Kemasan PT. Abutama
Authors: Arifin Moh Mawan , Agustin Meilan
Published: June 2023

Industri Air Minum Dalam Kemasan (AMDK) di Indonesia saat ini memiliki peluang bisnis yang baik, dikarenakan tingkat konsumsi masyarakat akan air mineral terus mengalami peningkatan. PT. Abutama merupakan produsen air minum telah mulai diproduksi sejak tahun 2019. Penjualan produk AMDK “Aisy” yang dilakukan selama tahun 2019 belum mencapai target penjualan. Target penjualan yang masih belum tercapai disebabkan karena perusahaan masih melakukan tahap pengenalan produk dan jumlah agen penjual yang masih sedikit. Tujuan penelitian ini untuk membuat perencanaan strategi bagi perusahaan AMDK dalam mengembangkan usahanya sehingga dapat bersaing di pasar global. Metode yang digunakan adalah analisis Strenght, Weakness, Opportunity, Threatment (SWOT) dan Business Model Canvas. Hasil  penelitian menunjukkan PT. Abutama berada dalam posisi bertahan. Perusahaan memiliki sisi kelemahan dan ancaman yang banyak. Perusahaan harus melakukan strategi perbaikan pada bagian internal dengan meminimalkan permasalahan yang ada dan situasi di eksernal dengan melakukan beberapa perbaikan agar bisa mendapatkan peluang yang lebih baik. Hasil analisis dengan Business Model Canvas yaitu value proposition menciptakan produk yang berkualitas, variasi produk, harga terjangkau dan menjalin komunikasi dengan beberapa perusahaan. Komunikasi dengan pelanggan melalui telepon, website, revenue stream dengan peningkatan penjualan produk dan key resources dengan memperbaiki fasilitas produksi.
Characterization of Climatic Parameters and River Flow Capacity on Electricity Generation in Jebba Dam, Nigeria
Authors: Liman Hadiza Muhammad , Nwaerema Peace , Yisa Jacob
Published: June 2023

This study examined the characterization of climatic parameters and river flow capacity on electricity generation in Jebba Dam, Nigeria. It is a known fact that climatic parameters of rainfall, temperature and evaporation have the capacity to influence reservoir inflow and outflow as well as hydropower generation. The study collected secondary data of climatic parameters, reservoir inflow and outflow as well as hydropower generation from Mainstream Energy Solution Limited in 2018. The data were analyzed using averages and represented in graphs and charts. The results showed that there was rise in power generation from July to December with November having the highest power generation of 432.5MWH. Reservoir inflow and outflow rose from July to December with September having the highest discharge of 4860m3/sec inflow and 4858 m3/sec outflow. There was noticeable rise in rainfall pattern from May to November with September having the highest rainfall regime of 330.4mm in the Jebba river basin. However, February and November had the highest temperature regime of 360C each in the Jebba river basin. The highest evaporation rate was recorded in March having 25m3/sec during the period. Finally, the study has revealed the effects of these climatic parameters on the reservoir flow and hydropower generation in the Jebba dam. Therefore, the government should strictly consider the phenomenon of climate change as it affects hydroelectric power generation in Nigeria without further delay.
Characterisation of a Group I Intron in the 18S rDNA of Thecamoeba (Amoebozoa; Discosea)
Authors: Corsaro Daniele
Published: June 2023

During an investigation of amoeba rDNA sequences, a group I intron was identified in the 18S rDNA of Thecamoeba aesculea (Amoebozoa; Discosea) at position S956. Secondary structure of Thecamoeba intron and phylogenetic analysis suggest that it is affiliated with other S956 introns occurring in distantly related amoebae such as acrasid (Percolozoa; Heterolobosea) and myxogastrid (Amoebozoa; Mycetozoa) slime moulds. This is the first report of a nuclear intron occurring within the genus Thecamoeba.
Sustainable Rural Community Development Experiences and Lessons
Authors: Kapsalis Takis Ap
Published: June 2023

The purpose of this article is multifactorial. The primary question we investigate here refers to human barriers and established practices in a local county that obstructs pathways towards a sustainable future, as well as the measures taken to overcome difficulties and their societal impact. We base our analysis solely on the experience gained during the 2012-2015 planning period for the sustainable development of Vytina county-Greece. Our research focuses on sustainable development and its dependence on local community behaviours, as well as alternative ways for citizen involvement in the development process in order to avoid obstacles encountered in established bottom-up methodologies. Societal constraints include the complexity of communications and relationships between residents, the community's existing internal processes, a complex external environment, and a lack of shared vision which all contribute to the ego of the inhabitants, and to their time availability. These constraints represent obstacles and threats. The fundamentals of the planning process should neutralize and override these obstacles. It is important to recognize and measure these constraints and evaluate their societal impact. Weak predictions/estimates, inconsistent goals, top-down policy decisions, short-sighted planning, resistance to change, and intractable local government can all be barriers to bottom-up methodologies. The bottom-up process, fair and meaningful, is somewhat cumbersome and requires time to mature in order for sustainability practices to be effective. But the pilot application can help foster alternative approaches that allow the citizen to enter the era of sustainability easier and faster. The prerequisite is the existence of a rich cultural heritage. Facing all these problems in the planning for the sustainable development of a local community today, I wonder how a sustainable outer space civilization can be accomplished in the distant future when we have finally arrived at, what Michio K aku refers to as, the God equation or theory of everything.
Biostatistical Analysis on the Generation Mechanism of Neutral Consensus and Opinion Polarization
Authors: Zhao Bin , Jiang Xia
Published: June 2023

We establish a biostatistical model to describe the generation mechanism of neutral consensus and opinion polarization. The paper also explores the formation mechanism of the "screaming effect", "echo chamber effect" and "information cocoon room" and studies how to use reasonable strategist avoid the "screaming effect" and "echo chamber effect" according to the biostatistical model built.