bluuebunny/crossref_metadata_2025 huggingface dataset:
Trade and economic relations of Eastern Caucasus with Russia (17th–18th centuries)
Authors: Salikhova L. B.
Published: July 2024

Importance. In the 17th–18th centuries the development and strengthening of trade and economic relations between the peoples of Eastern Caucasus and the Russian state took place, which became systematic since the second half of the 16th century. The urgency of the work is due to the importance of studying these relationships, identifying the ways in which trade and economic relations took place. The aim of the paper is to consider the relations of the peoples of Eastern Caucasus with Russia, to reflect the role of cities, villages acting as trade centers between peoples.

Materials and Methods. The object of the study was trade and economic relations of the peoples of Eastern Caucasus with Russia. The main scientific methods used in the paper can be attributed – the method of description, synthesis, analysis, the principle of objectivity, etc.

Results and Discussion. It is noted the growing role of cities as trade centers, through which trade routes passed to different countries. Thus, Tersky city is a link in the trade of the peoples of Eastern Caucasus with the Russian state. Local feudal owners are given free trade for loyalty to the Russian state, which testified to the further development of the productive forces of the region and external economic relations. The peoples of Eastern Caucasus traded with the townspeople and merchants of Astrakhan, from Terki to Astrakhan went goods and products of Caucasian production and from Astrakhan to the mountain people are delivered Russian, Western European and Eastern goods. In the 18th century, in Eastern Caucasus there are trading centers, where the exchange of goods is conducted between the plain and the mountainous parts.

Conclusion. Initially, the trade of the peoples of Eastern Caucasus with the neighboring peoples is of an exchange nature. Gradually there is a transition to the development of commodity and monetary relations, which is characteristic for foreign trade operations. The local feudal elite are mainly involved in trade, which managed the process through their own people, and later the middle classes became involved.
The possibilities of using historical data on Tambov church monuments of the late 18th – first half of the 19th century in the development of an interactive map
Authors: Vorobeva E. M.
Published: July 2024

Importance. A number of factors are considered: the possibility of providing relevant historical information to a wide audience, the use of modern technologies for analyzing and distributing historical information, and the significant interest of historians in working within the framework of the methodology used. The purpose of the study is to offer a resource for popularizing the church history of the region. The main sources are used in the work are plans of the city of Tambov and documents from the funds of the Tambov City Duma (16) and the Mezhevaya Chancellery (29) of the State Archive of the Tambov Region, some reference and visual materials, as well as a view of the city of Tambov in 1799.

Research Methods. Both classical historical methods and the methodology of historical informatics are used.

Results and Discussion. The relevance of modern information technologies use in scientific and educational activities is substantiated. A historiographical analysis of the problem has been carried out, which relates to the theoretical part of the study. The problems associates with the localization of lost objects on modern maps and their solutions are described, which can be attributed to the practical part. Variants of references of the church history objects of Tambov city for an interactive map of the church history objects of Tambov at the end of the 18th – first half of the 19th century are proposed for consideration. The process of collecting and systematizing information for the formation of historical references of ancient religious buildings in Tambov: the Znamenskaya Church, the Church in the name of the Great Martyr Barbara and the Church of the Life-Giving Trinity is described.

Conclusion. The main result of the study is the images demonstration of attaching cartographic, visual and descriptive data on the history of specific monuments of church history to maps.
Organizational features of the reform of local self-government in 1870 in the county towns of the Central Chernozem region (on the example of the Tambov province)
Authors: Kuznetsov V. V.
Published: July 2024

Importance. Cities in Russian history have always been distinguished by their special social, political, economic and cultural status, which was also manifested in internal organizational aspects. For almost two and a half centuries, there has been a domestic city government, which has gone through many modernization stages and has become an important socio-political institution in the field. In this regard, the issues of continuity and traditions in its development remain important. The purpose of the study is to identify and analyze the organizational features of the urban reform of 1870 in the counties of the Central Chernozem region.

Materials and Methods. The source basis of the study is the materials of the State Archive of Tambov region and published publications of the Tambov Provincial Statistical Committee. Various legal acts are used to describe the mechanisms of regulatory regulation of urban selfgovernment. The methodological basis of the research is based on the principles of objectivity, historicism and consistency.

Results and Discussion. The process of implementing the reform of urban self-government in 1870 in the provinces of the Central Chernozem region lasted for several years and was mostly completed only in 1873. This situation was explained by a number of reasons: firstly, the law did not contain norms aimed at the transition from the old system of urban governance to the new one, secondly, the legislator did not set a strict time frame related to the implementation of the reform, thirdly, urban societies themselves slowed down the process of reorganizing local government, making numerous mistakes in procedural There are internal disagreements among the electors.

Conclusion. The formation of a new system of self-government in the county towns of the Central Chernozem region had a number of common legalized and arbitrary features. The “delayed” procedure for the enactment of the law made it possible to organize elections in provincial centers and form the practice of work of supervisory authorities. In some cities, the implementation of the reform was slowed down due to the incompetence of representatives of urban societies involved in the modernization of local governments. Finally, the censorship policy of the state and the unsettled mechanism for nominating candidates served as the basis for serious competition and numerous complaints that delayed the process.
The life path of G.H. Bumagin
Authors: Vorob’ev D. A.
Published: July 2024

Importance. In 2024, G.H. Bumagin, secretary of the Leningrad and Novgorod regional Committees of the CPSU(b), who played a very important role in many events of the Battle for Leningrad, as well as in the restoration of the Novgorod region in the first post-war years and actively studying the activities of the partisans and underground workers of the Leningrad region in the last years of his life, will turn 120 years old. Now, there are no biographical fundamental works about him, and in books and articles, researchers most often described his work during the Great Patriotic War and in the first post-war years. The purpose of the study is to examine in detail his life path. Its tasks are to establish life periods and their chronological framework, to determine the criteria for choosing chronological frameworks, to describe each life period and its features, to establish the results and contribution of G.H. Bumagin to the events that he participated in.

Materials and Methods. The research is based on archival materials from the Central State Archive of Historical and Political Documents of St. Petersburg and the Novgorod Museum-Reserve. A descriptive-narrative, biographical methods, analysis and periodization are used for it.

Results and Discussion. Based on archival materials, it is possible to describe the formation of G.H. Bumagin as the party leader of the Leningrad region before the outbreak of the Great Patriotic War and the development of his career path. In addition, his work on the formation of the resistance movement in the first months of the Battle for Leningrad, the leadership of the Commission of the eastern districts of the Leningrad region and the leadership of the Novgorod region in the first post-war years is described.

Conclusion. G.H. Bumagin had a difficult fate. A guy from a poor family who lived almost halfstarved, made every effort to get out into the world. He decided to do this by serving in the Red Army. Thanks to her, he was able to develop a political career in Leningrad and became secretary of the Leningrad and then Novgorod Regional Party Committee. They tried to blacken his name during the Leningrad case. Even though he was imprisoned without any evidence, he endured adversity with his family and, after rehabilitation, adjusted his life. When he retired, he had another front of work – studying the Resistance movement, which he led in the first months of the war. His accumulated material and work experience were subsequently useful for compiling memoirs and reports on the history of the partisan and underground movements of the Leningrad, Novgorod and Pskov regions. He left valuable materials after his death, which formed the basis not only for this article, but also for other historical works.
Unquenchable creative fervor (To the 75th anniversary of Yu.A. Mizis)
Authors: Kanishchev V. V. , Lyamin S. K. , Strekalova N. V.
Published: July 2024

The work is dedicated to the anniversary of the Dr. habil. (History), Professor Yuri Alexandrovich Mizis. The main scientific achievements realized by Yu.A. Mizis over the years of his professorial and teaching activities, as well as the work carried out by him in the field of scientific interests, are highlighted.
Long-term Exposure to Ambient Air Pollution and its Association with Mental Well-Being, Depression and Anxiety: A Nationally Representative Study
Authors: Pinheiro Guedes Lara , Sousa-Uva Mafalda , Gusmão Ricardo , Martinho Clarisse , Matias Dias Carlos , Da Conceição Virgínia , Gomes Quelhas Carlos , Saldanha Resendes Daniel , Gaio Vânia
Published: July 2024

Introduction: Exposure to ambient air pollution may play a role in the onset of common mental disorders like depressive and anxiety disorders. The association of long-term exposure to particles smaller than 10 μm (PM10) with these diseases remains unclear. This study aimed to estimate the association of long-term exposure to PM10 with mental well-being and the frequency of probable diagnosis of common mental disorders.Methods: A nationally representative cross-sectional study was done in mainland Portugal. Long-term exposure was estimated through one-year average concentrations of PM10, calculated with data from the Portuguese Environment Agency, attributed individually considering individuals’ postal codes of residence. The mental well-being and the probable diagnosis of common mental disorders were ascertained through the five-item Mental Health Inventory scale. Linear and Robust Poisson regression models were computed to estimate change percentages, prevalence ratios (PR), and their 95% confidence intervals (95% CI).Results: The median (interquartile range) concentration of PM10 was 18.6 (15.3 - 19.3) μg/m3. The mental well-being score was 72 (56 - 84) points, on a scale from 0 to 100. A probable diagnosis of common mental disorders was found in 22.7% (95% CI: 20.0 to 25.6). Long-term exposure to PM10 was associated with a non-statistically significant decrease in the mental well-being score [for each 10 μg/m³ increment in one-year average PM10 concentrations, there was a 2% (95% CI: -8 to 4) decrease], and with a non-statistically significant increase in the common mental health frequency (PR = 1.012, 95% CI: 0.979 to 1.045).Conclusion: We did not find statistically significant associations between long-term exposure to PM10 and mental well-being or the frequency of probable diagnosis of common mental disorders. These results may be explained by the reduced variability in the exposure values, given the geographical distribution and functioning of the network of air quality monitoring stations. This study contributes with evidence for low levels of air pollutants, being one of the first to adjust for individual and aggregate-level variables. Moreover, to the best of our knowledge, this was the first nationally representative, population-based study conducted on the Portuguese population using real-life data. Maintaining a robust and nationwide air quality monitoring network is essential for obtaining quality exposure data.
Obra e seus leitores
Authors: Moraes Paulo Henrique Rigolin de
Published: July 2024

Articulando aspectos da relação entre a obra e seus leitores, este texto busca analisar a forma pela qual a primeira edição (publicada em 1958) do ensaio “Os donos poder”, de Raymundo Faoro, foi recebido por críticos literários e cientistas sociais. Num contexto em que o Estado era tido como um importante indutor de mudanças sociais e os instrumentos teóricos utilizados pelo autor ainda causavam certa estranheza, esta primeira versão não foi recebida com o mesmo entusiasmo que a edição definitiva do texto de 1975. Nesse sentido, olhar para os leitores da primeira edição do texto ajuda a compreender parte dos processos que resultaram na consolidação de um texto clássico do pensamento social brasileiro e, através desse caso específico, ajuda a deslindar relações entre as ideias e seu tempo histórico.
Structural relationships between covert narcissism, SNS addiction, self-focused attention, and interpersonal ability
Authors:   The Association of Korea Counseling Psychology Education Welfare, SEO Hyun-Jin , PARK Chan-Young , SHIN Seo-Won
Published: July 2024

The purpose of this study is to investigate the relationship between covert narcissism, social network service addiction tendency, self-focused attention, and interpersonal ability. A structural equation model including the four variables was formulated based on previous studies. 324 middle school students who lived in Gyeongsangnam-do answered the survey and the data were analyzed. Results indicated that covert narcissism was positively related to SNS addiction tendency and self-focused attention, and negatively related to interpersonal ability. Also, self-focused attention and interpersonal ability had a mediation effect, respectively, in the relationship between covert narcissism and SNS addiction tendency. Lastly, all direct and indirect effects were verified in the paths from covert narcissism to SNS addiction tendency. Based on the results, the ways to support adolescent with SNS addiction were discussed.
International Research Trends on Peer Supervisionin Counseling
Authors:   The Association of Korea Counseling Psychology Education Welfare, KIM Hee-Kyung , PARK Hye-Ran , YOO Soon-Hwa
Published: July 2024

To systematically examine international trends in peer supervision research in the field of counseling, this study analyzed 59 articles published in English in international journals between 1969 and December 2023. The results are summarized as follows. First, the topics of peer supervision research were identified in the following order: outcome studies, topic overviews, case studies, etc. Second, the research methods were qualitative, literature review, quantitative, and mixed methods. Third, in terms of research subjects, practicing counselors and school counselors accounted for 57.63% of all studies. Fourth, peer supervision was most often conducted once a week for 60 to 90 minutes over a period of 15 weeks or less. Finally, peer supervision outcome measures were categorized and presented. Based on the results of these analyses, directions and implications for future peer supervision research in Korea were suggested.
PERUBAHAN PERILAKU MANDATORY ACTIVITY DAN ONLINE SHOPPING ACTIVITY AKIBAT PANDEMI COVID-19
Authors: Budiarto Arif
Published: July 2024

Teleworking activities, which have been developing since 1970 and initially aimed at employee efficiency, proved applicable during the COVID-19 pandemic. Supported by the advances of internet-based information technology, teleworking activities could be carried out optimally, leading to the emergence of various new innovations. One such innovation is app-based online shopping, which facilitates users in ordering ready-to-eat meals or groceries, known as food delivery. The COVID-19 pandemic, which spread to all countries globally, also impacted individual behaviors in activities and travel, especially with government advisories to implement lockdowns to reduce the spread of the Coronavirus. This study was conducted to examine individual behaviors in carrying out online activities in the Surakarta Agglomeration Area. Data was collected through a home interview survey from March to June 2021, involving 402 respondents. Online activities, particularly for shopping and ordering food, were hypothesized to have high value during COVID-19, leading to a comprehensive dependency on online activities, especially shopping. The research results, however, contradicted the initial hypothesis. 88.8% of individuals stated that they "never" shopped online or did grocery shopping online, with the remaining 11.2% engaging in online shopping. This discrepancy is suspected to occur because, although online shopping is easy to conduct, it requires adequate financial strength to support it.
THE WORLD OF USERS AND USED KNOWLEDGE IN INTERNATIONAL BUSINESS
Authors: Kuklin V. , Ivin L. , Mekhovych S. , Zakharchenkov O.
Published: July 2024

The problem of the dominance of fragmented and superficial knowledge in modern education is discussed, which is important for the implementation of international business. The entire structure of knowledge of contemporaries is layered, and only the resulting surface layers of information and methods of obtaining results have been mastered. Unfortunately, deep-seated basic knowledge, which is the basis of modern approaches in technology, is not mastered. The behavior of people is also dominated by the superficial attitudes of the user, the desire to delve into the deep layers and important details of the description of phenomena and technologies are virtually absent. This can create problems in the formation of creative approaches to progress, reduce creative productivity and slow down the progress not only of basic sciences, but also of ordinary technologies useful to society. It is revealed which user skills are important for the creator. It is very important to hear from users in a timely manner and together with them to solve the problem that may be the cause of distrust and abandonment of the product. All products are useful for specific users, but there is no perfect product. This encourages the author to constantly add new features and test hypotheses. The testing process will be effective when the problem is solved together with a user who knows everything about the product and is always ready to participate in its improvement. In order to be on the same page with the user, it is necessary to develop certain skills. A list of such skills is given. The essence and meaning of onboarding is revealed.
European and African-specific plasma protein-QTL and metabolite-QTL analyses identify ancestry-specific T2D effector proteins and metabolites
Authors: Cruchaga Carlos , Yang Chengran , Gorijala Priyanka , Timsina Jigyasha , Wang Lihua , Liu Menghan , Wang Ciyang , Brock William , Wang Yueyao , Sung Yun Ju
Published: July 2024

Initially focused on the European population, multiple genome-wide association studies (GWAS) of complex diseases, such as type-2 diabetes (T2D), have now extended to other populations. However, to date, few ancestry-matched omics datasets have been generated or further integrated with the disease GWAS to nominate the key genes and/or molecular traits underlying the disease risk loci. In this study, we generated and integrated plasma proteomics and metabolomics with array-based genotype datasets of European (EUR) and African (AFR) ancestries to identify ancestry-specific muti-omics quantitative trait loci (QTLs). We further applied these QTLs to ancestry-stratified T2D risk to pinpoint key proteins and metabolites underlying the disease-associated genetic loci. We nominated five proteins and four metabolites in the European group and one protein and one metabolite in the African group to be part of the molecular pathways of T2D risk in an ancestry-stratified manner. Our study demonstrates the integration of genetic and omic studies of different ancestries can be used to identify distinct effector molecular traits underlying the same disease across diverse populations. Specifically, in the AFR proteomic findings on T2D, we prioritized the protein QSOX2; while in the AFR metabolomic findings, we pinpointed the metabolite GlcNAc sulfate conjugate of C21H34O2 steroid. Neither of these findings overlapped with the corresponding EUR results.
Proteo: A Framework for the Generation and Evaluation of Malleable MPI Applications
Authors: Martín-Álvarez Iker , Aliaga José I. , Castillo Maribel , Iserte Sergio
Published: July 2024

Applying malleability to HPC systems can increase their productivity without degrading or even improving the performance of running applications.This paper presents Proteo, a configurable framework that allows to design benchmarks to study the effect of malleability on a system, and also incorporates malleability into a real application. Proteo consists of two modules: SAM allows to emulate the computational behavior of iterative scientific MPI applications; and MaM is able to reconfigure a job during execution, adjusting the number of processes, redistributing data and resuming execution. An in-depth study of all the possibilities shows that Proteo is able to behave like a real malleable or non-malleable application in the range [0.85, 1.15]. Furthermore, the different methods defined in MaM for process management and data redistribution are analyzed, concluding that asynchronous malleability, where reconfiguration and application execution overlap, results in a 1.15x speedup.
Study on the Correlation between Shear Wave Elastography and MRI Grading of Meniscal Degeneration
Authors: Ye Ran , Xiong Hua-Hua , Liu Xiao , Yang Jun-Xing , Guo Jian-Dong , Qiu Jian-Wen
Published: July 2024

Background Shear Wave Elastography (SWE) offers quantitative insights into the hardness and elasticity characteristics of tissues. The objective of this study is to investigate the correlation between SWE of the menisci and MRI-assessed degenerative changes in the menisci, with the aim of providing novel reference source for improving non-invasive evaluation of meniscal degenerative alterations.
Methods The participants in this study were selected from patients who underwent knee joint MRI scans at Shenzhen Hospital (Futian) of Guangzhou University of Chinese Medicine, from February 2023 to February 2024. The anterior horn of the medial and lateral meniscus was evaluated using SWE technique. The differences in elastic values of meniscus among different MRI grades were compared. The correlation between elastic values and MRI grades, as well as various parameters, was analyzed. Using MRI Grade 3 as the gold standard, the optimal cutoff value for meniscal tear was determined. The intraclass correlation coefficient (ICC) was employed to evaluate the reliability of repeated measurements performed by the same observer.
Results A total of 104 female participants were enrolled in this study, with 152 lateral menisci (LM) and 144 medial menisci (MM) assessed. For the male group, 83 individuals were included, with 147 LM and 145 MM evaluated. The results demonstrated statistically significant differences in the elasticity values of the menisci at the same anatomical sites across different MRI grades (P < 0.001). Within the same grade, the MM had higher elasticity values than the LM, showing a statistically significant difference (P<0.001). The elasticity values of the menisci were higher in males compared to females. There were statistically significant positive correlations between the elasticity values of the menisci and age, BMI, and MRI grade. The ICC for repeated measurements within the observer demonstrated good reliability (>0.79).
Conclusions A significant positive correlation was observed between the SWE values of the menisci and the degeneration levels determined by MRI.
Does Terminology Matter When Measuring Stigmatizing Attitudes About Weight? Validation of a Brief, Modified Attitudes Toward Obese Persons Scale
Authors: Martin-Wagar Caitlin A , Melcher Katelyn A , Attaway Sarah E , Bennett Brooke L , Thompson Connor J , Kronenberger Oscar , Penwell Taylor E
Published: July 2024

Objective Commonly used terms like “obese person” have been identified as stigmatizing by those with lived experience. Thus, this study sought to revise a commonly used measure of weight stigmatizing attitudes, the Attitudes Toward Obese Persons (ATOP) scale.Methods The original terminology in the 20-item ATOP (e.g., “obese”) was compared to a modified version using neutral terms (e.g., “higher weight”). Participants (N = 832) were randomized to either receive the original or modified ATOP.Results There was a statistically significant difference, with a low effect size (d=-0.26), between the scores of participants who received the original ATOP (M = 69.25) and the modified ATOP (M = 72.85), t(414) = -2.27, p = .024. Through principal component analysis, the modified ATOP was found to be best used as a brief, 8-item unidimensional measure. In a second sample, confirmatory factor analysis verified the fit of the brief, 8-item factor structure.Conclusions Findings suggest a modified, brief version of the ATOP (ATOP-Heigher Weight; ATOP-HW) with neutral language is suitable for assessing negative attitudes about higher-weight people. The ATOP-HW may slightly underestimate weight stigma compared to the original ATOP. Further examination of the terminology used in weight stigma measures is needed to determine how to best assess weight stigma without reinforcing stigmatizing attitudes. The findings of the present study suggest that the use of neutral terms in measures of anti-fat bias is a promising solution that warrants further investigation.
Healthcare Outcomes in Hospitals: Development of a conceptual framework
Authors: KC RAJA SHREE , A Bhooma Devi , S Nithya Priya , P Praveen Kumar
Published: July 2024

Healthcare organisations are progressively confronted with progress and improvements with respect to service provisions they provide to their patients. They are always expected to develop strategies in order to provide better services at patients’ convenience. Flexibility is always given utmost priority when it comes to service sector. It is always considered as an important aspect for obtaining competitive advantage. This can satisfy the fluctuating patient demands. In this paper, the association between service convenience flexibility for patients and health care outcomes are examined. Several dimensions of service convenience flexibility with respect to healthcare setting are investigated and fundamentally inspected. The relationship between service convenience flexibility for patients and the healthcare outcomes is an crucial area of study in healthcare research. Service convenience flexibility will directly influence patient satisfaction with respect to healthcare services. Patients always find it very easy to fix appointments, access care whenever needed, and obtain higher levels of satisfaction. This will positively impact the patient health outcomes. Because happy and satisfied patients will be engaged in the care and recover at a faster rate. They will positively adhere to treatments. The convenience as well as flexibility in hospitals can always empower patients in order to take an important role in management of patients’ health. For example, patients will be more convenient with online appointments, online portals, appointments, etc. This helps in enhancement and betterment healthcare delivery which can contribute towards improved patient satisfaction.
Indicators for Risk of Hip Fracture in Elderly Women Without Osteoporosis
Authors: Bian Yuquan , Zhao Jinhui , He Shizan , Cao Jiaqing , Jiang Dajun , Jia Weitao
Published: July 2024

Purpose: Fracture prediction in non-osteoporotic elderly women is often neglected due to their relatively normal bone mineral density (BMD). This study aimed to identify key risk factors and develop a predictive model for hip fracture risk in this particular population.
Methods: The study included 125 patients in the experimental group and 109 in the control group. Data of BMD, 25-hydroxyvitamin D (25(OH)D), C-terminal telopeptide of type I collagen (β-CTX), N-terminal mid-fragment of osteocalcin (N-MID), and demographic characteristics were collected for analysis. Univariate and multivariate logistic regression analyses were performed to identify independent risk factors, and prediction models were developed and assessed using the Receiver Operating Characteristic (ROC) curve and DeLong test.
Results: After adjusting all covariates and confounders, β-CTX (adjusted-OR 1.004 [1.002-1.006], P<0.01), N-MID (adjusted-OR=0.816 [0.743-0.897], P<0.01), 25(OH)D (adjusted-OR=0.884 [0.841-0.928], P<0.01) and height (adjusted-OR=1.245 [1.058-1.487], P<0.01) persisted as risk factors in the multivariate regression model. Among these, 25(OH)D exhibited the highest predict value (AUC=0.85), with an optimal cutoff value established at 24.07 ng/ml. The AUC value of predictive model including height, β-CTX, N-MID and 25(OH)D was significantly greater (AUC=0.902, P<0.05) than that of other combinations.
Conclusion: In non-osteoporotic elderly women, 25(OH)D demonstrates a higher predictive capability than BMD, with levels below 24.07 ng/mL significantly increasing hip fracture risk. The proposed predictive model, composed of height, β-CTX, N-MID, and 25(OH)D, offers excellent predictive value, evidenced by an AUC of 0.902.
Trial registration: The study protocol was reviewed by the Ethics Committee of Shanghai Sixth People’s Hospital (Shanghai, China; approval number, 2017-152), and successfully registered with the China Clinical Trial Center, clinical trial registration number ChiCTR-ONC-17013389 (registered in November 15, 2017).
Clinicopathologic study of the adult rhabdomyoma in the oral and maxillofacial region
Authors: Zhang Lei , Huang Xiao-feng , Li Hui-ling , Xia Shu , Chen Xiu-juan , Chen Sheng , Yang Yan , Ye Chuan-jin , Ni Yan-hong , Zhou Ting
Published: July 2024

Objectives
This study aimed to explore the clinicopathological characteristics of adult rhabdomyoma (A-RM) in the oral and maxillofacial region.
Materials and Methods
We analyzed seven cases of A-RM in the oral and maxillofacial region, focusing on the clinical manifestations, imaging findings, histopathological features, differential diagnosis, treatment, prognosis, and relevant literature review.
Results
The age range of the seven A-RM cases was 4 to 83 years old. Six cases were male and one case was female. Three cases occurred on the floor of the mouth and one case on the tongue. All A-RM cases presented as slow-growing, painless masses. The lesions were lobulated, red-brown nodules with well-defined margins. Histologically, they consisted of densely packed, large, round and polygonal cells with abundant granular eosinophilic cytoplasm. Cross-striations and vacuoles were observed in the cytoplasm. Tumor cells were positive for desmin, myoglobin and myogenin, and some tumor cells were positive for SMA, MyoD1 and S-100 protein. PAS staining was also positive among tumor cells and could be digested by diastase.
Conclusion
Histological examination is the main diagnostic criterion for A-RM. The detection of cross-striations and immunohistochemical expression of myogenic proteins in the cytoplasm are crucial for accurate diagnosis. Radical resection is the main treatment modality with generally favorable prognosis.
A Novel Hybrid Deep Learning IChOA-CNN-LSTM Model for Modality-Enriched and Multilingual Emotion Recognition in Social Media A Novel Hybrid Deep Learning IChOA-CNN-LSTM Model
Authors: Geethanjali R. , VALARMATHI A
Published: July 2024

In the rapidly evolving field of artificial intelligence, the importance of multimodal sentiment analysis has never been more evident, especially amid the ongoing COVID-19 pandemic. Our research addresses the critical imperative to comprehend public sentiment across the multifaceted dimensions of this crisis by integrating data from various modalities such as text, images, audio, and videos sourced from platforms like Twitter. Conventional methods, which primarily focus on text analysis, often fall short in capturing the nuanced intricacies of emotional states, necessitating a more comprehensive approach. To tackle this challenge, our proposed framework introduces a novel hybrid model, IChOA-CNN-LSTM, which leverages Convolutional Neural Networks (CNNs) for precise image feature extraction, Long Short-Term Memory (LSTM) networks for sequential data analysis, and an Improved Chimp Optimization Algorithm (IChOA) for effective feature fusion. Remarkably, our model achieves an impressive accuracy rate of 97.8\%, outperforming existing approaches in the field. Furthermore, by integrating the GeoCoV19 dataset, we enable a comprehensive analysis spanning linguistic and geographical boundaries, thereby enriching our understanding of global pandemic discourse and furnishing indispensable insights for informed decision-making in public health crises. Through this holistic approach and innovative techniques, our research contributes significantly to advancing multimodal sentiment analysis, providing a robust framework for deciphering the complex interplay of emotions amidst unprecedented global challenges like the COVID-19 pandemic
Agricultural Input Subsidies and the Marketing of Agricultural Products
Authors: Panahian payam , Borimnejad Vali , Samari Davood , Nozari Niv
Published: July 2024

The effect of agricultural input subsidies for farmers and other factors on the marketing of agricultural products is investigated in this paper. We first constructed a PLS-SEM; based on that, we designed survey questionnaires for Karaj city in the Alborz Province. The internal model shows that the method of production has the strongest effect on purchase intentions, followed by online purchases and input subsidies. Empirical analysis based on the questionnaire and PLS-SEM shows that the advertising variable has the strongest effect on the economic factors variable, followed by input subsidies and the distribution system. The path relationships between advertising, input subsidies, and the distribution system and economic factors are significant and show that all three variables are relatively strong predictors of economic factors.
The Epidemiological Characteristics of Mycoplasma Pneumoniae Infection and Coinfection among Children in Central China from 2018 to 2023
Authors: Mao Jieyu , Niu Zhili , Liu Mengling , Li Liangyu , Zhang Haiyue , Li Ruiyun , Zhang Pingan , Wu Xiaojun
Published: July 2024

Background
Mycoplasm pneumomiae(M. pneumoniae, MP) is a common cause of reapiratory infections in humans, particularly among children and adolescents. This study investigates the epidemiological characteristics of MP infection among children and its relationship with coinfections to provide guidance for local MP prevention strategies.
Methods
After data screening based on the inclusion and exclusion criteria, a total of 163,058 pediatric patients with Acute Respiratory Tract Infection (ARTI) were enrolled in the study, ranging from January 1, 2018, to December 31, 2023.
Results
From 2018 to 2023, a total of 49,936 cases tested positive for MP, resulting in an overall positive rate of 30.62%. During this period, the annual positive rates were as follows: 45.92%, 32.23%, 22.84%, 16.22%, 16.26%, and 42.93%, respectively. The highest positive rate was observed in autumn (35.13%, P < 0.001). School-aged children exhibited the highest positive rate (40.09%), while infants had the lowest (25.32%, P < 0.001). Furthermore, the positive rate among girls (34.15%) was higher than that among boys (28.01%, P < 0.001). Among patients with MP infection, 14.27% were found to have coinfection with other pathogens, with viral infections accounting for 71.36% and bacterial infections for 28.64%. Notably, infants were more prone to coinfection with multiple pathogens (48.98%, P < 0.001).
Conclusions
MP infection is prevalent in children, with notable seasonal and age-dependent variations in positive rates. Coinfection with other pathogens is common, particularly in infants.
Experimental investigation of the evolution of bed topography in an asymmetrical confluence
Authors: Bombar Gokcen , Cardoso António Heleno
Published: July 2024

This study assessed the time evolution of the bed morphology of six experiments performed by Bombar and Cardoso (2020) on mobile bed confluences. These experiments were characterized by a unique junction angle, a fixed plan layout of the converging channels, constant water discharges and water discharge ratio, and six combinations of the converging sediment transport rates. The end aspect ratio of both channels was sufficiently large to avoid strong wall effects, and the flow was always subcritical and rough turbulent. The bed sediment was a uniform non-ripple forming sand. Detail analysis of the time evolution of the bed morphology showed that balanced fluxes of sediments through the boundaries of the system were a sufficient condition of equilibrium within the range of variables covered by the study. The most important morphological features of the confluence were discussed for several time instants, including those referring to the equilibrium phase. The equilibrium features essentially complied with the morpho-dynamic models reported in the literature for mobile bed confluences, meaning that the time evolution and the end (equilibrium) values of the bed morphologies reported in this paper can be used to validate CFD models thought of as predictive tools of confluence morpho-dynamics. Two experiments are, indeed, ideal for this purpose since they converged to static equilibria, and wrong predictions cannot be attributed to oscillations of the bed, whereas those models may only be able to predict the average, equilibrium values of the bed features of experiments run with sediment supply into the main channel and characterized by the movement of bedforms.
Occurrence and exposure risk assessment of heavy metals and lanthanon in green tea samples cultivated in Hangzhou area
Authors: Wang Shuting , Fan Jicai , Gong Like , Ren Ren , Jin Quan
Published: July 2024

The concentration of heavy metals and lanthanon in 120 green tea samples grown in Hangzhou area were investigated by inductively coupled plasma mass spectrometry (ICP-MS). Except for Hg (69.2%), Sb (98.3%), Se (93.3%) and Sn (94.2%), the detection rate of the other 11 elements were all 100.0%. The mean concentration of heavy metals in tea showed the following order: Mn>Al> Ba> Cu> Ni> Cr> Pb> Sn> Li> V> Se> As> Cd> Sb>Hg. Mn was the highest element found in the tea samples with a concentration ranging from 202.00 to 2010.00 mg/kg and a mean of 836.00 mg/kg. The lowest element was Hg, with a concentration ranging from ND to 0.017 mg/kg and the mean concentration was 0.0033 mg/kg. And all the 120 samples did not exceed the standard limit value of heavy metal. The pollution level of heavy metals indicated that the single pollution index and comprehensive pollution index of green tea produced in Hangzhou area are far below 0.7, which belong to the clean and safety level. Health risk of inhabitant via consuming green tea was conducted and the HI value was 40.75%, less than 100%, which indicates that these chemicals pose no risk to human health in Hangzhou area.
Psychotropic Polypharmacy Impairs Walking Independence in Post-Stroke Patients
Authors: Matsumoto Ayaka , Yoshimura Yoshihiro , Nagano Fumihiko , Shimazu Sayuri , Bise Takahiro , Kido Yoshifumi , Shiraishi Ai , Kuzuhara Aomi , Hamada Takenori , Yoneda Kouki
Published: July 2024

Background Psychotropic drugs are associated with adverse outcomes in older adults. However, evidence on the effect of psychotropic use on walking ability in post-stroke patients is lacking. Aim This study examined the association between psychotropic medication use and walking independence in post-stroke patients. Methods This retrospective cohort study included stroke patients admitted for convalescent rehabilitation at a Japanese hospital between 2020–2022. Psychotropic medications (benzodiazepines, hypnotics, antipsychotics, antidepressants) prescribed at admission were recorded. The primary outcome was walking independence at discharge, defined as a Functional Independence Measure (FIM) walk score ≥ 6. Logistic regression analyses examined the association between the number of psychotropic drugs and walking independence, adjusting for potential confounders. Results Of the 709 patients enrolled, 559 (mean age 75.5 years, 52.8% male) were included in the analysis. At admission, 25.4% of patients used psychotropic drugs. In the adjusted analysis, the number of psychotropic medications was independently associated with lower walking independence at discharge (OR 0.620, 95% CI 0.428–0.897, p = 0.011). Hypnotic use specifically showed a negative impact on walking independence (OR 0.331, 95% CI 0.154–0.708, p = 0.004). However, psychotropic drug use was not significantly associated with improvement in FIM-motor scores. Conclusion Greater psychotropic polypharmacy at admission, particularly with hypnotics, was associated with reduced likelihood of achieving walking independence after stroke rehabilitation. Judicious use of psychotropic medications may be warranted when ambulation is a critical goal for older post-stroke patients.
Experience with stress and the coping process in Chinese nursing and medical students: A constructivist grounded theory study
Authors: Zhang Wei , Cao Zhiyan , Ye Xiaoli , Shen Tong , Zhao Fangfang
Published: July 2024

Background
Nursing and medical students often face a variety of stressors due to the special needs of their majors, such as relatively heavy academic tasks. Their ability to cope with stress affects their health and personal development.
Objectives
To explore the experiences of nursing and medical students coping with stress and construct an interpretive understanding of these experiences from the perspective of nursing and medical.
Design:
A constructivist grounded theory approach.
Settings:
This study included participants from eight departments of a university in Southeastern China.
Participants:
Purposive sampling and snowball sampling were used to select nursing and medical students with experience coping with stress.
Method
Audio-recorded interviews were conducted between May 2020 and January 2021. The data analysis included initial coding, focused coding, and theoretical coding using the constant comparative method and memo writing.
Results
Thirty participants were included in this study. “Physical and mental harmony” was identified as the core category. The following seven categories were conceptualized: enlightening exploration, internal adjustment, seeking social support, emotional support, positive self-awakening, individual degeneration, and asymmetrical resources.
Conclusion
The findings identified that the goal of nursing and medical students in coping with stress is to achieve and maintain physical and mental harmony. It is necessary to help nursing and medical students achieve mental health by understanding and intervening in their stress-coping process, the facilitating factors, obstacles, such as those found in the research, and the context of their occurrence.
WITHDRAWN: Effect Of Using Sterilized Water By Utilizing Non-Thermal Plasma On Hydroponics Growing Of Capucha Lettuce
Authors: Gamal Areej , Shams Mohamed A. , Elkhawas Husin , Hegab Khaled K.
Published: July 2024

Chemical composition and disinfection of fresh Capucha Lettuce are very important. Contamination of irrigation water with pathogenic microbes and its transfer to vegetable plants is considered a major problem facing both internal and external marketing of fresh vegetables crops. Therefore, evaluation of using sterilized water by utilizing non-thermal plasma on hydroponics growing of Capucha Lettuce was aim of this research. Practical experiment was statistically designed, executed and analyzed as factorial experiment in complete randomized block design to evaluate both quantity and quality of growing hydroponics capuchi-lettuce on treated water. Microbial Laboratory test was executed to confirm that there are no pathogenic microbes on the fresh capuchi-lettuce grown on the treated water. Chemical analysis processes were executed to determine chemical composition of the produced Capucha Lettuce. Using non-thermal plasma treated water in hydroponics capuchi-lettuces growing has significant effect on vitamins concentrations, nutrients such as “Potassium, Calcium, magnesium, phosphorus, vitamins (A. C, B4, K)” concentrations, and physical properties capuchi-lettuces. Using non-thermal plasma treated water produce safe fresh capuchi-lettuces and free of pathogenic bacteria.
Preclinical development of a dual targeting bicistronic gene therapy approach for the treatment of wet age-related macular degeneration
Authors: Tam Lawrence CS , Joel Josephine , Stampoulis Dimitris , Little Abigail , Walton Amy , Atkinson-Dell Rebecca , Devine Maya , Hill Jake , Esteve-Rudd Julian , Ellis Scott
Published: July 2024

Age-related macular degeneration (AMD) continues to be a leading cause of severe vision impairment affecting millions worldwide. The late stages of AMD are characterized by outer retinal atrophy (geographic atrophy, GA), or neovascularization associated with subretinal and/or intraretinal exudation (exudative neovascular or ‘wet’ AMD). Intravitreal (IVT) administration of anti-vascular endothelial growth factor (VEGF) therapies has dramatically improved vision preservation for wet AMD (wAMD) patients. However, current Standard of Care (SoC) has significant shortcomings and the benefits of anti-VEGF therapy in the real-world setting fall short of the vision gains observed in randomized clinical trials. This is thought to be attributable to drug burden to patients, lack of therapeutic durability due to progression of underlying macular atrophy and refractility to treatment. Vectorized anti-VEGF therapy has been shown to be effective in reducing drug burden clinically but is unlikely to address the progression of the underlying GA driven by complement-mediated inflammation. Here, we aim to address this unmet need by developing a bicistronic gene therapy vector co-expressing aflibercept and Factor H-like protein 1 (FHL-1) to target the pro-angiogenic and pro-inflammatory environment of wAMD. In vitro assays confirmed the anti-angiogenic and complement inhibitory properties of the bicistronic vector. Recombinant AAV8 (rAAV8)-mediated co-expression was detected for up to 4 weeks following subretinal delivery in wild type (WT) mice. In a mouse laser-induced choroidal neovascularization (CNV) model, subretinal delivery of bicistronic vectors significantly reduced both CNV leakage and lesion. These results demonstrate that a single subretinal administration of bicistronic vector may provide an effective treatment option for wAMD and may also prolong patient’s visual outcomes by preventing the underlying progression of GA.