bluuebunny/crossref_metadata_2025 huggingface dataset:
Новая тактика в комплексном лечении хронического вирусного гепатита «C»
Authors: Ваугаmov I.P.  , Valiyev A.H.  , Abdullayeva O.A.  , Javadzde V.N.  , Borodayeva T.L.
Published: February 2021

Цель исследования. Цель настоящего исследования заключалась в разработке новой тактики в комплексном лечении хронического гепатита С с применением ультрафиолетового облучения.Материалы и методы. Исследования были проведены на 60 больных обоего пола в возрасте от 30 года до 60 лет с диагнозом «хронический вирусный гепатит С», поступивших в клинику инфекционных болезней Национального Научно-Исследовательского Института Медицинской Профилактики им. В. Ахундова в 2019 году. В качестве исследования была использована кровь больных с подозрением на вирусный гепатит С. НСV антиген, IgМ анти-НС определяли методом иммуноферментного анализа с использованием коммерческих наборов производства Канады.Результаты. В статье представлены результаты по разработке новой тактики в комплексном лечении хронического вирусного гепатита С. Установлены биохимические и иммунологические маркеры эффективности предложенного (подхода к лечению хронического вирусного гепатита С с применением ультрафиолетового облучения.
Potensi Vitamin C sebagai Feed Additive untuk Mengurangi Stress pada Ternak Puyuh
Authors: Lestariningsih Lestariningsih , Puspitasari Riska Mei , Setiawan Andi , Fernandi Fuguh
Published: February 2021

Tingginya suhu lingkungan didaerah tropis menyebabkan ternak unggas mengalami stress panas. Stresss panas pada unggas khususnya puyuh dapat memicu timbulnya berbagai penyakit, mempengaruhi pertumbuhan dan produksi telur. Cara yang bisa dilakukan untuk mengurangi stress panas pada puyuh ialah dengan memberikan feed additive berupa vitamin C, mengingat vitamin C mengandung antioksidan yang dap  at digunakan untuk meredam radikal bebas yang menyebabkan stress pada puyuh. Tujuan ditulisnya artikel ini adalah untuk mengetahui seberapa besar manfaat vitamin C sebagai feed additive untuk mengurangi stress pada ternak puyuh. Materi dan metode yang digunakan dalam penulisan artikel ini adalah kajian pustaka yang selanjutnya dianalisis menggunakan pendekatan diskriptif kualitatif.  Hasil dan pembahasan berisi tentang Stress pada unggas yang ditandai dengan peningkatan tekanan darah, otot, sensitivitas saraf, gula darah dan respirasi. Ketika stress terjadi secara berkelanjutan maka tubuh akan mengaktifkan hypothalamic-pituitary-adrenal cortical system. Penggunaan antioksidan yang murah bisa dengan memanfaatkan vitamin C, tak hanya itu vitamin C juga memiliki kelebihan lain seperti vitamin C, yakni mampu mengembalikan radikal tokoferol menjadi alfa tokoferol yang stabil.
Peran Penting Mikroba Rumen pada Ternak Ruminansia
Authors: Yasin Muhammad Yusuf , Hupron Mas’ud Zakqi , Khomarudin Muhammad , Hadiarto Andika Fajar , Lestariningsih Lestariningsih
Published: February 2021

Masalah utama yang dihadapi dalam pemenuhan daging dan susu sapi di Indonesia yaitu rendahnya SDM khususnya dalam pengetahuan ternak khusunya ruminansia. Peternak tidak mengetahui anatomi ternak ruminansia yang memiliki lambung ganda yaitu rumen, retikulum, omasum dan abomasum, sehingga mempengaruhi strategi dalam pemberian pakan yang menentukan produktivitas ternak sapio potong maupun perah. . Rumen berperan penting karena di dalam rumen terdapat mikroba yang berperan dalam perombakan berbagai nutrisi pakan khususnya pada perombakan serat kasar sehingga berpengaruh terhadap produktivitas ternak. Peningkatan pengetahuan tentang rumen khususnya mikroba rumen merupakan salah satu solusi dalam masalah ini yang bertujuan agar peternak memiliki strategi dalam menentukan pakan yang dapat dicerna oleh ternak. Materi dan metode menggunakan data sekunder yang diambil dari jurnal peneliti dan dan buku kemudian dianalisis dengan metode pendekatan deskriptif analitik. Rumen memiliki tiga jenis mikroba yaitu bakteri, fungi (jamur), dan Protozoa. Peranan bakteri di dalam rumen yaitu sebagai perombak serat kasar seperti selulosa dan hemiselulosa dan peran dari fungi di dalam rumen yaitu sebagai awal jalan membuka dinding sel yang sudah tercerna serta peranan dari protozoa yaitu berkontribusi dalam proses pencernaan dan pemecahan materi organic di dalam rumen
El testamento de la madre del Inca Garcilaso
Authors: Miró Quesada S. Aurelio
Published: February 2021

En abril de 1945 tuve la singular satisfacción de encontrar en el Cuzco el testamento de Isabel Suárez, nombre cristiano y español de la Princesa incaica Chimpu Ocllo, madre del egregio historiador Inca Garcilaso de la Vega.

Tal descubrimiento ha llegado a dar, por primera vez, corporeidad a la figura elusiva y misteriosa de la madre del insigne mestizo, a la que hasta ahora sólo se podía considerar como una sombra tutelar y distante. En efecto, las únicas referencias concretas que se poseían hasta hoy eran las que proporcionaba el propio Inca en sus obras, de donde han seguido repitiéndolas todos durante trescientos cincuenta años. No había, fuera de ello, un sólo informe, una sola comprobación documental que pudiera ratificar o modificar las escasas palabras del cronista.
La poesía de Enrique Bustamante y Ballivián
Authors: Fabio Xammar Luis
Published: February 2021

Meditar sobre la poesía, es la más alta y difícil tarea para el hombre, pero también la que más íntimamente lo purifica en su contacto con el mundo. Se pierde la noción y la medida de lo terreno al ingresar al ámbito de la pura irrealidad, con sus lúcidas exactitudes de astronomía celeste, y también con la nota constante y grave de la angustia del hombre, razón y medida de su existencia.
Las teorías vitalistas
Authors: H. Urteaga Horacio
Published: February 2021

La hipótesis del vitalismo en la Historia, fué iniciada a principios del siglo XIX por Juan Bautista Vico, el que en su famoso libro "Las Revoluciones Palingenésicas" sostuvo que los pueblos (i) recorren en su desarrollo ciclos vitales; nacen, crecen y mueren como los organismos, describiendo en esta trayectoria cerrada y fatal, sus corsi y recorsi circulares, sus avances y retrocesos.
La Universidad de San Marcos
Authors: Valega J. M.
Published: February 2021

La sabiduría, en la ancianidad histórica, había sido un atributo exclusivo de los selectos mentales. Patrimonio de una verdadera clase social, privilegiada depositaria de la ciencia. De una ciencia suprema, que dominaba el bien y el mal, porque capacitaba al hombre para el conocimiento pleno de las leyes de la vida, y de la función máxima de la humanidad sobre la tierra.
La tragedia sexual de Leonardo de Vinci
Authors: Palomino Arana Helí
Published: February 2021

Tal es el título de la obra en la que Freud enfoca la personalidad psicoanalítica del gran pintor del renacimiento italiano. Si como afirma Markun "muchos hombres de genio han nacido con tendencias homosexuales" tales como Oscar Wilde, Walt, Whitman, Tchaikowski y otros, ¿por qué no había de ponerse en duda la inmortal figura, apuesta y elegante, de Leonardo de Vinci?

En efecto, Freud sin considerar la homosexualidad como un tercer sexo innato al nacimiento, sino más bien como el producto de "un íntimo enlace infantil de carácter erótico, olvidado después por el individuo, a un sujeto femenino, generalmente la madre, enlace provocado o favorecido por la excesiva ternura de la misma y apoyado después por un alejamiento del padre de la vida infantil del hijo", llega a descubrir en Leonardo una homosexualidad ideal y un tipo aproximado al neurótico obsesivo, constituyendo su actividad investigadora la "meditación.obsesiva" y sus coerciones las "meditaciones del abúlico".
Afectos vencen finezas
Authors: Peralta Barnuevo y Rocha Pedro de
Published: February 2021

Creación literaria.
Premisas para una historia de la crítica de arte en el Perú
Authors: Castrillón Vizcarra Alfonso
Published: February 2021

Se puede decir, sin temor a equivocarnos, que la Crítica de Arte una creación "burguesa: Diderot, defensor del lacrimoso Greuze, era miembro de la burguesía pre-revolucionaria; Baudelaire, quien instaba a los burgueses para que dedicasen su tiempo a la fornación de la sensibilidad, así como lo dedicaban con tanto empeño al florecimiento de sus negocios, también pertenecía a un sector de la burguesía, con especial interés en abrirse paso en un mercado todavía incipiente.
Ulises después de Homero
Authors: Magris Claudio
Published: February 2021

“Nada –escribe Paul Valéry– demuestra más seguramente la potencia de un creador como la infidelidad o la insubordinación de su criatura. Cuanto más él la ha hecho viviente, tanto más la ha hecho libre. Hasta la rebelión de ella exalta a su autor: Dios lo sabe... Estos personajes... los ha generado de tal manera que pueden volverse, por medio suyo, instrumentos del espíritu universal: ellos van del otro lado de lo que fueron en su obra... los ha consagrado para siempre a la expresión de algunos extremos de lo humano y de lo inhumano; y, por tanto, desvinculado de cada aventura particular”. Valéry escribe estas páginas en la introducción a Mon Faust, refiriéndose a aquellas figuras que reaparecen continuamente en la literatura de todo tiempo y país, como Antígona, Fausto, Don Juan, Ulises.
Combination effect of hot smoking and vacuum packaging on quality parameters of refrigerated thornback ray (Raja clavata Linnaeus, 1758)
Authors: KARSLI Barış , ÇAĞLAK Emre
Published: February 2021

In this study, hot smoking process was applied to thornback ray (Raja clavata), which is a non-target catch, and the product obtained was vacuum packaged and then stored at refrigerated conditions (4±1 °C) for 120 days. The nutritional, chemical, microbiological, and sensory changes in the products were examined every 15 days. After the hot smoking process applied to thornback rays, significant changes were observed in the nutritional composition of the products (P<0.05). Total volatile basic nitrogen (TVB-N), trimethylamine nitrogen (TMA-N), and thiobarbituric acid (TBA) values of smoked thornback rays increased during storage, and these values were determined between 23.11-98.06 mg/100 g, 2.48-7.33 mg/100 g, and 0.1-0.3 mg malondialdehyde/kg, respectively. It was determined that the total aerobic mesophilic bacteria (TAMB) count detected in the fresh sample decreased in smoked products due to the smoking process and the value was found below the detectable limit value (1.47 log CFU/g) during storage. As a result of the sensory evaluation, it was determined that the texture, odor, and flavor criteria of the smoked thornback rays were below the consumable limit value on the 120th day. According to the results, it was determined that the thornback ray vacuum packaged by hot smoking can be consumed safely for 105 days at 4±1 °C. This study shows that discarded thornback rays, which are a high protein food, can be transformed into high value-added products by applying different processing methods such as smoking and so can be evaluated as human food.
Gagasan Pengembangan Organisasi Kelitbangan dalam Usaha Memajukan Literasi dan Pembangunan Keagamaan
Authors: Murtadlo Muhamad
Published: February 2021

Menghadapi masuknya paham-paham transnasional yang berpotensi memecah belah relasi keagamaan baik internal umat beragama maupun eksternal beragama di satu sisi, dan di sisi lain kemudahan tehnologi informasi saat ini berpotensi menjauhkan masyarakat dari dunia perbukuan, menjadi tantangan terbesar literasi keagamaan yang menjadi core business Puslitbang Lektur, Khazanah Keagamaan dan Managemen Organisasi (selanjutnya penyebutan dalam tulisan ini cukup disingkat Puslitbang atau PLKKMO saja). Menghadapi kemungkinan dampak tehnologi informasi yang semakin liar dan berpotensi terjadi pendangkalan pemahaman umat beragama karena masyarakat lebih menyukai membaca pesan keagamaan lewat media sosial yang instan dari pada merujuk pada sumber aslinya (buku atau kitab) menjadikan posisi Puslitbang ini semakin vital ke depan.
Coroless, effective ingredient isolated from traditional Chinese medicine for the prevention and treatment of Covid-19
Authors: Leng Nie , Youdong Liang , Xinwei Liang
Published: February 2021

We believe that a good medicine for the prevention and treatment of Covid-19 requires three points: 1. Effectively inhibit the cells from being infected by Covid-19; 2. Quickly repair lung damage; 3. Non-toxic and harmless. Fortunately, from the treasure depot of Chinese traditional medicine, we found Kyllinga brevifolia Rottb, which is sufficient for three points and can be used for prevention, treatment and rehabilitation. Not only that, we have isolated the active ingredient of the Kyllinga brevifolia Rottb, named it Coroless, and verified that Coroless inhibits the Covid-19 from infecting cells through in vitro cell experiments.
Makalah Pluralisme Hukum di Indonesia
Authors: harianto heru
Published: February 2021

Pluralisme Hukum adalah munculnya suatu ketentuan atau sebuah aturan hukum yang lebih dari satu didalam kehidupan sosial.
COBA
Authors: Sinambela Gabriel David Pangihutan
Published: February 2021

file hanya coba jadi jangan baper
Tác động của nợ nước ngoài đến tăng trưởng kinh tế Việt Nam
Authors: AISDL
Published: February 2021

Việt Nam là một quốc gia đang phát triển nên cần nguồn vốn lớn để xây dựng cơ sở hạ tầng, đầu tư cho phát triển. Tuy nhiên, Việt Nam có thâm hụt ngân sách cao, tỷ lệ thu nhập, tỷ lệ tiết kiệm và dự trữ ngoại hối thấp dẫn đến không đủ nguồn lực đầu tư cho phát triển. Vì vậy, nguồn vốn vay bên ngoài là một trong những nguồn lực quan trọng để bù đắp thiếu hụt để phát triển đất nước, góp phần bắt kịp với các nước trong khu vực và thế giới. Tuy nhiên, vay nước ngoài càng nhiều có giúp nền kinh tế Việt Nam tăng trưởng cao bởi vì hàng năm Chính phủ phải dành gần 25% ngân sách để trả nợ? Dòng vốn nước ngoài tác động như thế nào đến đầu tư, tiêu dùng và thương mại cũng như tăng trưởng kinh tế của các nước đi vay? Nghiên cứu tác động của nợ nước ngoài đến tăng trưởng kinh tế Việt Nam trong giai đoạn 2000-2016 nhằm tìm ra câu trả lời cho những câu hỏi nêu trên.
An Initial Investigation of the Joint Classification of Hypomania- and Neurodevelopmental Disorder-Relevant Dimensions within the Hierarchical Taxonomy of Psychopathology
Authors: Stanton Kasey , McDonnell Christina G
Published: February 2021

We examined hierarchical structural models of psychopathology in samples of (a) adults recruited online and screened based on psychopathology history (N = 429) and (b) undergraduates (N = 529) to inform classification of neurodevelopmental disorder (NDD)- and hypomania-relevant dimensions within the Hierarchical Taxonomy of Psychopathology (HiTOP). Results differed across samples in some ways, but converged to indicate that some NDD- and hypomania-relevant dimensions aligned closely with different HiTOP spectra. For example, some hypomania-relevant dimensions (e.g., lability) overlapped strongly with the internalizing spectrum, whereas others (e.g., self-perceived charisma) were reverse-indicators of detachment. Examination of cross-sectional and prospective correlates for emergent factors also was informative in some ways. This included NDD-relevant and disinhibited externalizing dimensions associating robustly with treatment seeking history and recent experiences of distress. These results provide initial insights into classifying NDD- and hypomania-relevant dimensions within the HiTOP and indicate a need for future research in this area.
Ứng dụng mô hình logistic trong xếp hạng tín dụng khách hàng cá nhân tại Ngân hàng thương mại cổ phần Xuất nhập khẩu Việt Nam
Authors: AISDL
Published: February 2021

Tại Ngân hàng Thương mại cổ phần Xuất Nhập khẩu Việt Nam (Eximbank), tín dụng bán lẻ dành cho khách hàng cá nhân đang là định hướng phát triển hiện tại và trong thời gian sắp tới. Tuy nhiên, hiện tại, xếp hạng tín dụng tại Eximbank chỉ mang tính chất tham khảo, chưa được xem là cơ sở quyết định đối với việc cấp tín dụng cho khách hàng, đặc biệt là đối với khách hàng cá nhân. Mặt khác, hệ thống xếp hạng tín dụng của Eximbank được xây dựng dựa theo phương pháp chuyên gia kết hợp với mô hình điểm số, phụ thuộc nhiều vào năng lực và ý chí chủ quan của cán bộ đánh giá xếp hạng, điều này là một trong những nguyên nhân có thể làm tăng rủi ro tín dụng cho Ngân hàng.
PERBEDAAN ANTROPOLOGI HUKUM, SOSIOLOGI HUKUM DAN HUKUM ADAT
Authors: rahmi mutia
Published: February 2021

1.Antropologi hukum adalah ilmu pengetahuan yang berkaitan dengan manusia yang bersangkutan dengan hukum.Antropologi hukum pada dasarnya mempelajari hubungan timbal-balik antara hukum dengan fenomena-fenomena sosial secara empiris dalam kehidupan masyarakat; bagaimana hukum berfungsi dalam kehidupan masyarakat, atau bagaimana hukum bekerja sebagai alat pengendalian sosial (social control) atau sarana untuk menjaga keteraturan sosial (social order) dalam masyarakat.2.Sosiologi hukum merupakan studi hukum dalam perspektif ilmu sosial merupakan sebuah ikhtiar melakukan konstruksi hukum yang didasarkan pada fenomena sosial yang ada. Perilaku masyarakat yang dikaji adalah perilaku yang timbul akibat berinteraksi dengan sistem norma yang ada. Interaksi itu muncul sebagai bentuk reaksi masyarakat atas diterapkannya sebuah ketentuan perundang-undangan positif dan bisa pula dilihat prilaku masyarakat sebagai bentuk aksi dalam memengaruhi pembentukan sebuah ketentuan hukum positif. kajian sosiologi hukum adalah suatu kajian yang objeknya fenomena hukum, tetapi menggunakan optik ilmu sosial dan teori-teori sosiologis, sehingga sering disalahtafsirkan bukan hanya oleh kalangan non hukum, tetapi juga dari kalangan hukum sendiri.3.Hukum adat merupakan hukum asli Indonesia yang tidak terkodifikasi dalam peraturan perundang-undangan nasional. Hukum adat merupakan hukum tradisional masyarakat yang merupakan perwujudan dari suatu kebutuhan hidup yang nyata serta merupakan salah satu cara pandangan hidup yang secara keseluruhannya merupakan kebudayaan masyarakat tempat hukum adat tersebut berlaku. Hukum adat juga merupakan nilai-nilai yang hidup dan berkembang di dalam masyarakat suatu daerah. Ada sanksi tersendiri dari masyarakat jika melanggar aturan hukum adat.
Giải tích ngẫu nhiên và ứng dụng trong thị trường tài chính
Authors: AISDL
Published: February 2021

Giải tích ngẫu nhiên và ứng dụng trong thị trường tài chính : Luận văn ThS. Toán học: 60 46 01 06http://repository.vnu.edu.vn/handle/VNU_123/39531 Tóm tắt62 tr. + CD-ROMLuận văn ThS. Lý thuyết xác suất và thống kê toán học -- Trường Đại học Khoa học Tự nhiên. Đại học Quốc gia Hà Nội, 2014Electronic ResourcesNhà xuất bản: ĐHKHTNTrong bộ sưu tập: HUS - Master Theses01050001744.pdf Dung lượng : 368,93 kB Định dạng : Adobe PDF
"KAJIAN ANTROPOLOGI HUKUM DENGAN ILMU SOSIAL LAINNYA (34)"
Authors: Sapendra Rici
Published: February 2021

Istilah antropologi berasal dari bahasa yunani, asal kata anthropos berarti manusia, dan logos berarti ilmu. Dengan demikian, secara harfiah antropologi ilmu tentang manusia. Pendekatan yang digunakan dalam antropologi menggunakan pendekatan kuantitatif (positivistik) dan kualitatif (naturalistic). Tujuan dari ilmu antropologi untuk memperluas arena perbandingan di samping untuk merekam budaya sebelum budaya budaya itu lenyap dan mencari suatu bangsa atau kelompok yang belum pernah di teliti. Ilmu antropologi erat kaitannya dengan ilmu sosial lainnya seperti sosiologi, geografi, sejarah, ilmu politik, psikologi dan ilmu-ilmu sosial lainnya. Antropologi mulai berkembang pada abad ke-15 dan terus berkembang hingga sekarang.Dalam ilmu antropologi hukum dipelajari juga mengenai Peran, Status atau kedudukan, Nilai, Norma dan juga Budaya atau kebudayaan. Ke semuanya ini merupakan hal-hal yang sangat erat kaitannya dengan ilmu antropologi hukum.Pembahasan tentang ilmu antropologi dan struktur ilmunya jangan berhenti sampai pada makalah ini saja. Sebagai generasi muda yang berbudaya, kita harus tetap mengembangkan dan mengamalkan dalam kehidupan sehari-hari. Kami menyadari bahwa makalah ini jauh dari sempurna, maka dari itu kami menerima segala kritik dan saran guna keberlangsungan kami dalam menulis makalah agar lebih baik lagi
Makalah aturan penukaran
Authors: Muh.hajrim
Published: February 2021

Catatan menjelaskan tentang materi aturan penukaran dan bagaimna cara dan aturan yang ada didalam materi tersebut.
TWIST2 is differentially expressed in brain metastatic human breast cancer.
Authors: Mamoor Shahan
Published: February 2021

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with brain metastasis in humans with metastatic breast cancer. We found that the twist family bHLH transcription factor 2, encoded by TWIST2, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. TWIST2 mRNA was present at decreased quantities in brain metastatic tissues as compared to primary tumors of the breast. Importantly, expression of TWIST2 in primary tumors was significantly correlated with patient overall survival. Modulation of TWIST2 expression may be relevant to the biology by which tumor cells metastasize from the breast to the brain in humans with metastatic breast cancer.
Compassion practices
Authors: Condon Paul , Makransky John
Published: February 2021

Healthcare providers seek to access a power of sustainable, inclusive, and unconditional care and compassion for self and others beyond empathic distress, secondary trauma, and burnout. To support that goal, in this chapter, we present three compassion meditations that serve two purposes: 1) to empower the ability to be with your own difficult emotions and feelings in a healing way, and 2) to extend empathy and compassion to others with increasing sustainability and inclusivity. Providers can practice these meditations themselves and carry forward that practice into clinical work, both in their embodied presence to their patients and, if appropriate and beneficial, by explicitly sharing these practices with interested patients.
Automated Video Interview Personality Assessments: Reliability, Validity, and Generalizability Investigations
Authors: Hickman Louis , Bosch Nigel , Ng Vincent , Saef Rachel , Tay Louis , Woo Sang Eun
Published: February 2021

Organizations are increasingly adopting automated video interviews (AVIs) to screen job applicants despite a paucity of research on their reliability, validity, and generalizability. In this study, we address this gap by developing AVIs that use verbal, paraverbal, and nonverbal behaviors extracted from video interviews to assess Big Five personality traits. We developed and validated machine learning models within (using nested cross-validation) and across three separate samples of mock video interviews (total N = 1,073). Also, we examined their test–retest reliability in a fourth sample (N = 99). In general, we found that the AVI personality assessments exhibited stronger evidence of validity when they were trained on interviewer-reports rather than self-reports. When cross-validated in the other samples, AVI personality assessments trained on interviewer-reports had mixed evidence of reliability, exhibited consistent convergent and discriminant relations, used predictors that appear to be conceptually relevant to the focal traits, and predicted academic outcomes. On the other hand, there was little evidence of reliability or validity for the AVIs trained on self-reports. We discuss the implications for future work on AVIs and personality theory, and provide practical recommendations for the vendors marketing such approaches and organizations considering adopting them.
Understanding the Global Landscape of Digital Skill on Facebook
Authors: Levin Nadine , Redmiles Elissa M.
Published: February 2021

This extended abstract (originally published at TPRC48) describes a large-scale survey of the digital skills of over 38,000 people on Facebook. We find that up to one-third of the global population lacks key digital skills, validate the relevance of digital skill to Facebook behavior, and identify demographic, geographic, and experiential covariance in digital skills.
Yin and Yang of Positive Psychology and Addiction
Authors: Krentzman Amy R
Published: February 2021

As researchers begin applying positive psychology to addiction recovery, they might find it difficult to draw clear lines between reducing pathology and cultivating a reinforcing life in recovery.
Some Questions of Ethics in RCTs
Authors: Khera Reetika
Published: February 2021

Questions of ethics in Randomized Controlled Trials (RCTs) in development economics need greater attention and a wider perspective. RCTs are meant to be governed by the three principles laid out in the Belmont Report, but often violated them, e.g. when local laws are flouted. In other cases, the framework of the Belmont Report itself has proved inadequate: for instance, when there are unintended outcomes or adverse events for which no-one is held accountable. Primarily using RCTs conducted in India, this paper highlights eight areas of concern. RCTs also have a disproportionate influence on shaping research agendas and on policy. Though ethical issues have been raised, there has been little engagement from the RCT community – a manifestation of its power in the profession. As current safeguards (such as oversight by Institutional Review Boards) have failed to protect human subjects, the concluding section discusses possible ways to resolve these issues.
Pharmacognostical and pharmaceutical studies on the Lekhaniya Maha Kashaya
Authors: Balat Gaurav , Dei L.P. , Garg Ankit , Harisha CR , Shukla V.J.
Published: February 2021

The benign tumor that originates in the uterus it is called a uterine fibroid. The growths are typically benign, or noncancerous. The cause of fibroids is unknown. According to the Office on Women’s Health, up to 80 percent Trusted Source of women have them by the age of 50. However, most women don’t have any symptoms and may never know they have fibroids. In Ayurveda the herbal drugs esily available and no any side effect and an effort by this papper that Lekhaniya Maha Kashaya is useful. Aim: To standardies Lekhaniya Maha Kashaya pharmacognostically, physiochemically and phytochemically. Materials and Methods: Lekhaniya Maha Kashaya were collected and prepared powder and Yavkut in the Pharmacy, GAU, Jamnagar, were identified and authenticated at Pharmacognosy laboratory, IPGT and RA, Jamnagar. Results: The presence of Annular vessels of Haridra, Border pitted vessels of Chitraka, cork cells of Chirabilwa, Cork cells of Musta, Cork cells with brown content of Kustha etc. in Pharmacognostical study and in Pharmaceutical study of Lekahaniya maha kashaya powder, Loss on drying 30 % w/w, pH 6.5. Analytical study showed 7 spots at 254 nm and 6 spots at 366 nm and in yavkut, Loss on drying 6.5 % w/w, pH 6.5. Analytical study showed 7 spots at 254 nm and 6 spots at 366 nm Conclusion: These findings could be helpful in identification authentication and standardization of the Lekhaniya Maha Kashaya.
Acute and subacute toxicity profiles on siddha drug Thulasi Ennai in wistar rats
Authors: Sonitha S. , Sivaraman D. , Rani V.
Published: February 2021

Medicinal plants have been used in traditional medicines for their unmatched availability of bioactive compounds. Asthma is the most common chronic disease among children worldwide. It is ranked 16th among the leading causes of years lived with disability. Medicinal plants have placed a vital role in the siddha system of medicine over centuries to cure acute and chronic illness. The aim of the present study was to investigate toxicity analysis to evaluate safety of the siddha drug Thulasi Ennai in vivo in wistar albino rats. Thulasi Ennai is a polyherbal siddha formulation mentioned in the ancient siddha books and literature, indicated to cure childhood bronchial asthma. In this study, Thulasi Ennai administered orally at a single dose of 2000mg/kg body weight and monitored for 14 days. For subacute toxicity study, Thulasi Ennai was orally administered in different doses of 200,400mg/kg body weight, daily for 28 days. At the end of each study physical parameters, hematological, biochemical and histopathological analysis were evaluated. No animals in each group of acute or subacute toxicity study showed mortality or clinical signs of toxicity throughout the study. Hence, the results of the study indicate a safe toxicological profile of Thulasi Ennai.
Melaleuca alternifolia Australian Tea Tree oil as an effective antifungal agent topically for Tinea unguium (onychomycosis)
Authors: Welder Wendy M
Published: February 2021

The evolution of modern medical advances is often underestimated and that as little as a hundred years ago, none of the formulated antibiotics currently available existed. The germ theory was only substantiated because bacteria had been identified with the refining of microscopic technol-ogy and organisms that did not exist in context or conjunction to human disease. The connection between what appeared through the lens of a microscope slowly became the basis of the medical theories of human health and illness. This included the causative agents within all states of hu-man wellness. Humans started using plants and their essences long before they were able to rec-ord it. The scientific renaissance started the medical movement towards concrete concepts and reproducible results all bound by the scientific methods. This left little room for combinations of chemicals or plant constituents and compartmentalized human health into systems that worked best under strict control negating the concept of synergy. Human medicine is now moving out of the realm of being solely dependent on synthetic chemical formulations. Alternative and modern medical healers alike are starting to understand that both paths to human healing are needed to care for the many microbial assaults caused by bacteria, viruses, and fungi. Combing herbal folk-lore with modern chemistry is not a compromise but a middle way for better human health and illustrated with the use of Melaleuca alternifolia (Australian Tea Tree Oil) and modern antifungal agents used in conjunction to definitively cure the fungal infection starting with the causative fungi Tinea unguim and the condition of onychomycosis as an example.
Capacidad promotora del crecimiento en cebada (Hordeum vulgare) y potencial antagónico de Rhizobium leguminosarum y Rhizobium etli
Authors: Santillana Nery , Zúñiga Doris , Arellano Consuelo
Published: February 2021

La agricultura sustentable plantea mejorar la eficiencia de la fijación del nitrógeno mediante el uso de plantas (leguminosas) y bacterias (rizobio) competitivas, capaces de ser usadas en biofertilizaciónn, biorremediación y fitorremediación y de esta manera extender las ventajas de la simbiosis a otros cultivos. En tal sentido, las investigaciones se han orientado al estudio del rizobio como promotor del crecimiento de plantas leguminosas y no leguminosas, proceso conocido como capacidad PGPR (Plant Growth Promoting Rhizobacteria). El presente estudio se ejecutó con el objetivo de evaluar 19 cepas de Rhizobium leguminosarum y Rhizobium etli, considerando su capacidad promotora de crecimiento en cebada (Hordeum vulgare) y su potencial antagónico conAlternaria solani y Fusarium sp. La evaluación de la capacidad promotora se realizó en condiciones de invernadero y el potencial antagónico in vitro. El 89% de las cepas de Rhizobium evaluadas estimuló el crecimiento de las plantas de cebada, incrementando la materia seca total entre 8 a 37%. Se observó que el 63% de las cepas de rizobio mostraron potencial antagónico con A. solani y el 84% con Fusarium sp., con porcentajes de inhibición hasta de 49% y de 43% respectivamente. Se verificó que algunas cepas de R. leguminosarum y R. etli pueden promover el crecimiento de plantas de cebada y controlar hongos fitopatógenos como A. solani y Fusarium sp. en condiciones in vitro.
Producción de maíz con estrés hídrico provocado en diferentes etapas de desarrollo
Authors: Giménez Luis
Published: February 2021

El maíz es un cultivo de elevado potencial en producción de grano y es altamente sensible a las deficiencias ambientales. La disponibilidad hídrica es la principal limitante del ambiente que presenta Uruguay para el desarrollo de maíz, debido a la baja capacidad de almacenamiento de agua de los suelos, las elevadas demandas atmosféricas y la irregularidad de las precipitaciones (PP). El trabajo consistió en determinar los rendimientos de maíz en situaciones de bienestar hídrico (T1) y cuantificar las disminuciones de rendimiento generadas por la ocurrencia de estrés hídrico durante: el periodo crítico (PC) (T2), el llenado de grano (T3), la etapa vegetativa y el PC (T4); además se evaluó un testigo en secano (T5). El estrés hídrico en distintas etapas se generó a través de simuladores de sequía y el bienestar hídrico por medio de riego suplementario. Los resultados mostraron que el rendimiento sin deficiencias hídricas se ubicó entre 13,5 y 15,3 t ha-1 aproximadamente. Las deficiencias de agua durante el PC provocaron pérdidas de rendimiento aproximadas al 50% del potencial. El estrés hídrico en el llenado de grano generó disminuciones del rendimiento cercanas a 30% y las deficiencias acumuladas en la etapa vegetativa y el PC provocaron un descenso del rendimiento de 56%.
DEVELOPMENT OF METHODOLOGY FOR TRANSPORTATION FLEET STRUCTURE FORMATION
Authors: Iryna Lebid  , Tetyana Anufriyeva  , Luzhanska Nataliia
Published: February 2021

The paper proposes a methodology for transportation fleet structure formation based on the determination of the standard size fleet by carrying capacity using the criterion of the cost of transportation of 1 ton of cargo, which will be expedient if the number of shipments per day exceeds three times the estimated number of the model range of cars. At a lower intensity of daily shipments, it is necessary to form a standard size range of a vehicle fleet on the basis of a repetition of independent tests. The paper proposes a method of forming the structure of the fleet of vehicles based on determining the size of the fleet using the criterion of the cost of transportation of 1 ton of cargo, which is appropriate if the number of shipments per day exceeds three times the estimated number of cars. With a lower intensity of daily shipments, it is necessary to form a standard size range of the fleet on the basis of repeating independent tests.It has been established that the value of the coefficient of static use of the vehicle's carrying capacity is influenced by the number of intervals for dividing the series of carrying capacity, their length and uniformity, as well as the distribution law of the random value of the item. Violation of the uniformity of the intervals of the series of the carrying capacity of the car, the value of the coefficient can deviate from the average to 6.2% An increase in the number of intervals in a number of carrying capacities of vehicles from 2 to 3 contributes to a rapid increase in the coordination of the density of distribution of the batch volume and shipment to the structure of the vehicle fleet in terms of carrying capacity and is characterized by an increase in the coefficient of compliance on average from 0.65 to 0.75. An increase in the range of carrying capacity up to interval 5 increases the value of the compliance coefficient to 0.8, a further increase in the intervals causes an inversely proportional increase in the compliance coefficient. An increase in the number of car models from 1 to 3 causes a decrease in the cost of transportation in the range of 8% - 11.3%, depending on the degree of use of the vehicle fleet. Further expansion of the model range to 7 units practically does not affect the cost of transportation, and then its growth is observed due to an increase in the duration of downtime while waiting for the proper consignment. It was revealed that an increase in the average weight of a shipment by 2.3 times causes a decrease in the cost of transportation 1.79 times, and with this decrease in the weight of a shipment, an increase in the intensity of growth in the cost of transportation is observed.
Correlative Analysis of Massive Epistaxis and Pseudoaneurysms in Nasopharyngeal Carcinoma after Radiotherapy and a 10-Year Review
Authors: Ye Jing , Zeng Liang , Wan Wei , Luo Qing , Jiang Hongqun , Ye Jing
Published: February 2021

Objective: Massive epistaxis after radiotherapy for nasopharyngeal carcinoma (NPC) is a common clinical
critical illness, which often leads to death of patients. This article focuses on the relationship between
massive epistaxis and pseudoaneurysm after radiotherapy in patients with NPC and discusses clinically
relevant treatment strategies.
Methods: A review was performed in 21 patients with massive epistaxis after radiotherapy for NPC from
January 2011 to December 2019, and all of the patients were examined by computed tomography
angiography (CTA). We also reviewed the English literature over the past 10 years to analyse the
characteristics and related causes of pseudoaneurysms in terms of the clinical stage of NPC, course of
radiotherapy, and affected artery. An analysis was performed on the methods of endovascular interventional
treatment of such pseudoaneurysms.
Results: Among the 21 patients with massive epistaxis after radiotherapy for NPC, 19 (90%) cases had
accompanying bone destruction of the skull base; 13 cases (62%) showed tumor recurrence; 15 cases (71%)
were in stage III or IV of NPC; 14 cases (67%) had combined pseudoaneurysms, including 9 cases occurring
in the internal carotid artery (ICA) and 5 cases occurring in the external carotid artery (ECA). These data
were consistent with the results of literature review. On analysis with imaging, we found that such
pseudoaneurysms are associated with necrosis and infection of the local bone and soft tissue, and that the
petrous part of the ICA was the most common predilection site. We also found that 11 of 14
pseudoaneurysms caused sentinel hemorrhage in the initial phase. In addition to anterior and posterior nasal
packing, endovascular interventional therapy was the most important management option. All 14 patients
with pseudoaneurysms underwent endovascular interventional therapy, but 1 patient died due to
hemorrhagic shock during the procedure. Among the others, 9 patients underwent occlusion of the ICA or
ECA with a stainless-steel coil, and rebleeding did not occur again. One patient underwent selected vascular
embolization with a covered stent. Direct occlusion of the pseudoaneurysm was performed in 3 patients.
Conclusion: Pseudoaneurysm, which was a serious complication after radiotherapy in patients with NPC,
could cause massive epistaxis with high mortality. The formation of a pseudoaneurysm was closely
associated with a high carcinoma stage, re-radiotherapy, and local bone destruction and infection. Most
cases had sentinel epistaxis, which was considered the bleeding characteristic. The imaging material
prompted that pseudoaneurysm had a predisposition to the petrous part of the ICA, while the preferred
therapy was endovascular embolization treatment.
The Role of Chicken Eggs in Human Nutrition
Authors: Lei Shi , Lei Shi
Published: February 2021

Chicken eggs are one of the best source of high quality protein along with important vitamins and minerals. An increased egg production and consumption could significantly improve nutritional needs of adults and children. Eggs are also an economical source of nutrients for a healthy diet and life, playing a vital role in human nutrition.
Analisis Beban Kerja dan Konflik terhadap Kepuasan Kerja Karyawan
Authors: Mauraksa Azis , Danial R.Deni Muhammad , Norisanti Nor
Published: February 2021

The purpose of this study was to determine the effect of employee workload and conflict on job satisfaction. The method used in this study uses an associative method. Data collection techniques used by researchers in research is through observation, interviews, questionnaires, documentation and library research. Data analysis techniques used are multiple correlation techniques, the coefficient of determination and multiple linear regression analysis. Based on the calculation of categorizing the percentage of data scores it is known that the workload is in high criteria. This shows the workload on Sukabumi's Neptuns Screen Printing Convection. Based on the calculation of categorizing data, it is found that the value of the conflict criteria is. This means that conflicts that occur within the company Neptuns Screen Printing Studio can still be resolved. Conclusion, there is a significant influence between workload and conflict on employee job satisfaction

Keywords: Workload, Conflict, Job Satisfaction
Analisis Efektivitas Perusahaan dengan Model Du Pont System
Authors: Ramadhan Bagja Pasca , Samsudin Acep , Jhoansyah Dicky
Published: February 2021

This study aims to determine the Du Pont System model in analyzing the effectiveness of the company's operations in generating profits at PT. Gajah Tunggal Tbk. This study uses quantitative descriptive analysis techniques that are used to describe in measuring the effectiveness of the company after carrying out calculations with the figures that have been included in the components or formulas contained in the Du Pont System model that is the Profitability Ratio consisting of Net Profit Margins (Net Profit Margin) and Return on Investment (Return On Investment), then Activity Ratio which consists of Total Asset Turnover. Conclusion, the effectiveness of the company for five years is considered not good seeing the decline that occurred in several aspects that could affect the final value of the Du Pont System.

Keywords: Company Effectiveness, Du Pont System
Pengaruh Kompensasi dan Disiplin Kerja terhadap Kinerja Karyawan
Authors: Yulandri Yulandri , Onsardi Onsardi
Published: February 2021

The purpose of this research is to study compensation and work discipline on employee performance at PT (SBS) Sinar Bengkulu Selatan. The research method in this study uses quantitative research methods. The results of the study can be concluded regarding the respondents' perceptions about Compensation Location (X1) and Work Discipline (X2) Employee Performance results (Y) with the results of multiple linear regression obtained the following research results: Y = 14.876 + 0.277X1 + 0.795X2 analysis of responses R = 0.823 ( X1) -Y), 0.926 (X2-Y) and the coefficient of determination R2 = 0.521 or approximately (52.51%) through testing the hypotheses together (simultaneously) and individuals (partial) in this study using the f test and t test, compensation (X1) and work discipline (X2), = 0,000. Conclusion, significant significant contribution and work discipline to employees at PT (SBS) Sinar Bengkulu Selatan.

Keywords: Work Discipline, Employee Performance, Compensation
Analisis Struktur Aset Dalam Mengukur Aktivitas Dan Profitabilitas Perusahaan
Authors: Sukandi Gia Tamara , Norisanti Nor , Samsudin Acep
Published: February 2021

This study aims to determine the analysis of asset structure in measuring the activity and profitability of the household appliances sub sector listed on the IDX. This study uses descriptive quantitative method, secondary data in the form of financial statements of household appliances sub-sector 2015 to 2017. The analysis used is horizontal analysis to measure asset structure, accounts receivable turnover (RTO), inventory turnover (ITO), working capital turnover ( WCTO), fixed asset turnover (FATO), total asset turnover (TATO), asset return (ROA) and using industry standard averages. The results showed that for three periods PT. Integra Indocabinet Tbk has increased its assets and profits. Whereas PT. Chitose Internasional Tbk and PT. Kedaung Indah Can Tbk experienced a fluctuation in assets, and an increase in profit. PT. Langgeng Makmur Industri Tbk experienced a decline in assets and profits. Conclusion, the company that is said to be good is a company that exceeds the industry average. While companies with low values ​​are due to the value obtained does not always exceed the average industry standard.

Keywords: Activity, Asset Structure, and Company Profitability
Pengaruh Perputaran Kas terhadap Profitabilitas Perusahaan Sub Sektor Makanan dan Minuman
Authors: Cahyani Gianti Ajeng , Indrawan Andri , Kartini Tina
Published: February 2021

This study aims to determine the effect of cash turnover on the profitability of food and beverage sub-sector companies listed on the IDX. The study was conducted using quantitative methods using an associative approach. Samples were taken by purposive sampling technique. The data collected is secondary data with classical assumption test analysis techniques, multiple linear regression analysis, and hypothesis testing. The results showed that cash turnover partially had a negative effect on profitability with t test results of -2.666 with a significant value of 0.012. T-value of -2.666 <ttable 2.034, can be interpreted that Ha is accepted and Ho is rejected, meaning that cash turnover affects the company's ROA and a significant value of 0.012 <0.05, indicating a significant effect. Conclusion, cash turnover has a negative effect because the size of the profitability (ROA) is not influenced by cash turnover. Sometimes when cash turnover increases, the profitability of the company is actually smaller than the previous year, because profitability is not only influenced by cash turnover, but can also be influenced by the accounts receivable turnover and inventory turnover

Keywords: Cash Turnover and Profitability
Pengaruh Enterprise Risk Management Disclosure, Intellectual Capital Disclosure dan Debt to Asset Ratio terhadap Nilai Perusahaan
Authors: Deffi Leni Siti Rukmana , Cahyono Dwi , Aspirand Rendy Mirwan
Published: February 2021

This study aims to determine the effect of Enterprise Risk Management Disclosure, Intellectual Capital Disclosure and Debt To Asset Ratio on firm value. This research uses quantitative methods, involving a sample of 21 mining companies listed on the Indonesia Stock Exchange (IDX) for the 2015-2017 period. Primary data is collected from regular company reports. The results of the study using a partial test showed a significance value of 0.397 for the Enterprise Risk Management Disclosure variable, a significance value of 0.349 for the Intellectual Capital Disclosure variable and a significance value of 0.301 for the Debt To Asset Ratio variable. The calculated coefficient of determination results obtained a value of 0.111, which means the independent variable under study only affects the value of the company by 11%, while the remaining 89% of the company's value is influenced by other independent variables outside the variables used in this study. Conclusions, Enterprise Risk Management Disclosure, Intellectual Capital Disclosure and Debt to Asset Ratio have no influence on firm value.

Keywords: Enterprise Risk Management Disclosure, Intellectual Capital Disclosure and Debt To Asset Ratio, firm value.
Konstruksi Laporan Keuangan Berdasarkan Standar Akuntansi Keuangan Entitas Mikro, Kecil dan Menengah (SAK EMKM)
Authors: Yuwono Annisa Bulan Jasmine , Yulinartati Yulinartati , Afroh Ibna Kamelia Fiel
Published: February 2021

Tujuan penelitian ini adalah menganalisis proses penyusunan laporan keuangan Salad Bulan, kendala-kendala yang dialami selama penyusunan laporan keuangan dan kesesuaian bentuk laporan keuangan dengan format laporan keuangan dalam SAK EMKM. Metode penelitian ini adalah deskriptif kualitatif dengan pengumpulan data, menganalisis data, menginterpretasikan data dan diakhiri dengan kesimpulan berdasarkan analisis data. Hasil penelitian menunjukkan bahwa penyusunan laporan keuangan oleh peneliti dapat menentukan jumlah kas sebesar Rp. 32.565.000 dan penjualan Rp. 174.321.000. Simpulan, Salad Bulan belum menerapkan pelaporan keuangan yang sesuai dengan Standar Akuntansi Keuangan Entitas Mikro, Kecil dan Menengah (SAK EMKM) karena hanya dibuat berdasarkan kebutuhan dan pemahaman pemiliknya.

Kata Kunci: SAK EMKM, Standar Akuntansi Keuangan, UMKM