bluuebunny/crossref_metadata_2025 huggingface dataset:
Successful combination treatment of metastatic ductal carcinoma of the pancreas tail pT4N0M1(per). Clinical case
Authors: Glukhov E. V. , Davydov M. M. , Ivanov A. M. , Filatov A. A. , Shogenov M. S. , Dementieva E. V.
Published: October 2022

Pancreatic tail cancer has a poor prognosis and may be unresectable at the time of diagnosis, since it is asymptomatic and often has invasion into adjacent organs, and also has a high metastatic potential, where the target organs are the liver, lungs, bones, as well as the parietal and visceral peritoneum, adrenal glands. Radical resection of the pancreas in such cases is impractical. The gold standard of treatment is systemic chemotherapy. We describe the successful resection of locally advanced pancreatic tail cancer with metastases along the peritoneum of the large omentum after 14 courses of chemotherapy according to the mFOLFIRINOX (oxaliplatin 85 mg/m2 intravenously for 120 min, irinotecan 150 mg/m2 intravenously for 90 min, leucovorin 400 mg/m2 intravenously for 120 min, 5-fluorouracil 2400 mg/m2 intravenous infusion for 46 hours, cycle 14 days).
Retrospective analysis of the results of surgical management of osteochondral lesions of the talar dome
Authors:   Vreden National Medical Research Center of Traumatology and Orthopedics, Saint-Petersburg, Russian Federation, Pashkova E.A. , Sorokin E.P. ,   Vreden National Medical Research Center of Traumatology and Orthopedics, Saint-Petersburg, Russian Federation,   Pavlov First St. Petersburg State Medical University, Saint Petersburg, Russian Federation, Konovalchuk N.S. ,   Vreden National Medical Research Center of Traumatology and Orthopedics, St. Petersburg, Russian Federation, Fomichev V.A. ,   Vreden National Medical Research Center of Traumatology and Orthopedics, Saint-Petersburg, Russian Federation, Shulepov D.A. ,   Vreden National Medical Research Center of Traumatology and Orthopedics, Saint-Petersburg, Russian Federation, Demyanova K.A. ,   Vreden National Medical Research Center of Traumatology and Orthopedics, Saint-Petersburg, Russian Federation
Published: October 2022

Introduction Differences in the reported results lead to the lack of comprehension of whether the size of osteochondral lesion of talar dome is too big for successful usage of arthroscopic microfracturing and osteochondral autologous transplantation would be more preferrable. Aim To elicit the rate and causes of poor results after using two most common methods of operative treatment of patients with osteochondral lesions of the talus (OCLT) for elaboration of indications for surgical method of choice for this category of patients. Materials and methods This was a retrospective study that included analysis of archive data and subsequent examination of 80 patients (80 ankle joints), who underwent treatment for symptomatic OCL of the talus from 2014 to 2020. Mean time from the operation to examination was 20.5 ± 19.8 months. Results A significant increase in the results of FAOS, AOFAS and VAS scales after operative treatment were observed, as well as a significant decrease in lesion sizes (р < 0.05). Overall patient satisfaction and intensity of preoperative pain syndrome showed strong positive correlation with the sizes of lesions on preoperative CT scans, especially with relative sizes. The data analysis revealed the borderline values of relative OCLT sizes, thus allowing us to divide the results of treatment into predictably poor and predictably good. Discussion The elicited borderline values of relative OCLT sizes as well as elicited correlations can be used to specify indications for choosing the method of operative treatment for this group of patients, but further prospective evaluation should be carried out. Conclusion The borderline values of the relative OCLT sizes were found that allow for division into predictably good and poor treatment outcomes.
Radiological outcomes of 360° lumbar fusion in patients with Modic changes
Authors:   National Medical Research Center of Traumatology and Orthopedics n.a. N.N. Priorov, Moscow, Russian Federation, Baikov E.S. , Leonova O.N. ,   National Medical Research Center of Traumatology and Orthopedics n.a. N.N. Priorov, Moscow, Russian Federation, Krutko A.V. ,   National Medical Research Center of Traumatology and Orthopedics n.a. N.N. Priorov, Moscow, Russian Federation
Published: October 2022

Introduction A cascade of degenerative spine changes affects the structures including vertebral endplates and bodies of adjacent vertebrae that can be visualized on MRI imaging as Modic changes. The aim of the study was to assess the role of changes in the endplates and adjacent vertebral bodies in radiological results of monosegmental posterior lumbar interbody fusion (PLIF) in patients with degenerative lesions of the spine. Material and methods The design of the study was a monocenter retrospective comparative cohort study. The radiological results of PLIF performed in combination with transpedicular screw fixation for 122 patients with Modic changes in adjacent endplates and adjacent vertebral bodies were evaluated for interbody fusion, subsidence of interbody implants, segmental angle, interbody space height. The followup period was 1-2 years. Results Complete interbody fusion was seen in 94.4 % of Modic type 0 and in 77.3 % of Modic type II changes. Interbody cage subsidence occurred in 38.9 % Modic type I, 22.7 % in Modic type II, 9.1 % in Modic type III and in 11.3 % Modic type 0 changes. A significant decrease in the segmental angle was found in all types of Modic changes (p < 0.05) at 1-2 years with the greatest decrease noted in Modic type I (p = 0.000438). A significant decrease in the interbody space height was noted in all groups (p < 0.05) with the greatest decrease seen in Modic type I changes (p = 0.000438) and the minimum decrease noted in Modic type III changes (p = 0.000438). Discussion The role of the endplates and adjacent vertebral bodies in the results of surgical treatment was evident, and more research is needed to explore the sort of this relationship. Conclusions Modic changes in the endplates and adjacent red bone marrow showed a significant relationship with the radiological outcomes of monosegmental PLIF. The interbody fusion Tan grade I and Tan grade II was more common for Modic type 0 and less common for Modic type II changes. Subsidence of interbody implants was more common for Modic type I and less common for Modic type III changes (9.1%). Postoperative loss of interbody space height and segmental correction was common for Modic type I.
A Deep Learning Quality Control Loop of the Extrusion-based Bioprinting Process
Authors: Bonatti Amedeo Franco , Vozzi Giovanni , Chua Chee Kai , Maria Carmelo De
Published: October 2022

Extrusion-based bioprinting (EBB) represents one of the most used deposition technologies in the field of bioprinting, thanks to key advantages such as the easy-to-use hardware and the wide variety of materials that can be successfully printed. In recent years, research efforts have been focused on implementing a quality control loop for EBB, which can reduce the trial-and-error process necessary to optimize the printing parameters for a specific ink, standardize the results of a print across multiple laboratories, and so accelerate the translation of extrusion bioprinted products to more impactful clinical applications. Due to its capacity to acquire relevant features from a training dataset and generalize to unseen data, machine learning (ML) is currently being studied in literature as a relevant enabling technology for quality control in EBB. In this context, we propose a robust, deep learning-based control loop to automatically optimize the printing parameters and monitor the printing process online. We collected a comprehensive dataset of EBB prints by recording the process with a high-resolution webcam. To model multiple printing scenarios, each video represents a combination of multiple parameters, including printing set-up (either mechanical or pneumatic extrusion), material color, layer height, and infill density. After pre-processing, the collected dataset was used to thoroughly train and evaluate an ad hoc defined convolutional neural network by controlling over-fitting and optimizing the prediction time of the network. Finally, the ML model was used in a control loop to: (i) monitor the printing process and detect if a print with an error could be stopped before completion to save material and time and (ii) automatically optimize the printing parameters by combining the ML model with a previously published mathematical model of the EBB process. Altogether, we demonstrated for the first time how ML techniques can be used to automatize the EBB process, paving the way for a total quality control loop of the printing process.
Type 1 hypersensitivity from vitamin B12 injection: a case report
Authors: Khatrawi Elham Mohammed , Prajjwal Priyadarshi , Ranjan Raunak
Published: October 2022

Vitamin B12 is essential for the development of healthy nerves and red blood cells. Vitamin B12 deficiency is becoming widespread and most commonly affects the elderly, pregnant women, vegetarians, and patients with renal or intestinal diseases. Either parenteral vitamin B12 treatment or high-dose oral vitamin B12 treatment is an effective therapy regardless of etiology. Parenteral therapy using the intramuscular route is considered the most familiar treatment for vitamin B12 deficiency. Anaphylactic reaction after intramuscular injection is an uncommon and potentially serious side effect. In this study, we are documenting a case of anaphylactic reaction in a 50-year-old man after her second dose of intramuscular injection of cyanocobalamin. The purpose of this case report is to highlight the need to understand the rare life-threatening side effect of intramuscular cyanocobalamin. Health care providers should be vigilant while administering the intramuscular injection of cyanocobalamin to vitamin B12 deficient patients.
A CONSTRUÇÃO SOCIAL DA REALIDADE DE PETER BERGER E THOMAS LUCKMANN
Authors: Da Silva Moreira Alberto
Published: October 2022

Peter Berger foi um pensador que marcou a sociologia brasileira da religião, mas não só a sociologia, como a antropologia, a sociologia do conhecimento, as ciências da religião, a teologia e muitas outras áreas do saber. A Construção Social da Realidade, livro que escreveu em 1966 junto com seu colega e amigo Thomas Luckmann, foi traduzido para muitas línguas e se tornou rapidamente um clássico da sociologia do conhecimento. Junto com O dossel sagrado e Rumor de anjos esses três livros da fase mais antiga são as principais contribuições de Berger para a sociologia da religião. Nesse artigo exponho o conteúdo, analiso o contexto de surgimento e examino a possível relevância da obra A construção social da realidade para a atualidade.
A OBRA PERSPECTIVAS SOCIOLÓGICAS: UMA VISÃO HUMANÍSTICA DE PETER BERGER
Authors: Gonçalves Eliane
Published: October 2022

O presente artigo é uma versão reescrita e ligeiramente ampliada da conferência proferida em 17 de setembro de 2020 na abertura do Webinário “Leituras de Peter Berger”. A partir de uma apreciação situada, particular e interessada, ofereço uma explanação comentada de sua obra mais longeva: Perspectivas Sociológicas, uma visão humanística, oferecendo exemplos de sua utilização em sala de aula em turmas de graduação em ciências sociais, além de conexões com outras abordagens teóricas.
REVISITANDO O DOSSEL SAGRADO: CONSIDERAÇÕES SOBRE A “IMAGINAÇÃO SOCIOLÓGICA DA RELIGIÃO” DE PETER BERGER
Authors: Silveira João Paulo De Paula
Published: October 2022

O artigo se dedica aos elementos fundamentais da sociologia da religião, de Peter Berger, na obra O Dossel Sagrado. O texto reproduz e amplia algumas das considerações apresentadas no seminário do Núcleo de Estudos da Religião, da Faculdade de Ciências Sociais da Universidade Federal de Goiás, realizado em setembro de 2020. Seu propósito é destacar aspectos definidores da imaginação sociológica do autor em um determinado momento de sua vida intelectual, no que toca à realidade religiosa moderna.
O RISO REDENTOR NO NOVO TESTAMENTO: EXPERIÊNCIA CÔMICA E TRANSCENDÊNCIA NOS TEXTOS NEOTESTAMENTÁRIOS
Authors: Leite Francisco Benedito
Published: October 2022

O presente ensaio contém uma proposta de leitura crítica de O Riso Redentor de Peter Berger, obra na qual nos dedicamos a entender a abordagem que o autor faz do material do Novo Testamento para construir sua teoria sobre a relação entre a transcendência e a comicidade. Em seguida, realiza-se no artigo uma avaliação crítica dessa leitura que Berger fez dos evangelhos e de textos do apóstolo Paulo. Para que essa avaliação fosse realizada, utilizamos a obra Humor escrita recentemente por Terry Eagleton, que chega a conclusões significativamente semelhantes ao conteúdo proposto por Berger em seu livro, sobretudo, no que diz respeito à relação entre transcendência e comicidade.
SANT’ANA E O MITO FUNDADOR DE ANÁPOLIS, GOIÁS
Authors: Reimer Haroldo , Vieira D’Abadia Maria Idelma , Souza Freitas Mirelle Antônia
Published: October 2022

O artigo busca evidenciar como as narrativas sobre Sant’Ana e a Festa de Sant’Ana funcionam como mito fundador ou etiológico para a cidade de Anápolis, em Goiás, Brasil. Busca-se num primeiro momento apresentar apontamentos sobre a compreensão e a pesquisa do mito e sua diversidade de formas. Depois são apresentadas discussões de como as festas religiosas, enquanto expressões de ritualidades, se relacionam com narrativas míticas que vinculam determinados entes sobrenaturais com o surgimento de cidades, visando sua proteção sacral. Aqui o foco está colocado nas festas religiosas em Goiás. Por fim, apresentamos a narrativa sobre Sant’Ana e a festas de Sant’Ana como mito fundador ou etiológico para a cidade de Anápolis, Goiás.
O ESPÍRITO SANTO E A VIVÊNCIA DA SINODALIDADE EM ATOS DOS APÓSTOLOS
Authors: Belinato Barreto Alfredo Rafael , Santos Adriano Lazarini Souza dos
Published: October 2022

O presente artigo versa sobre a relação fundamental existente entre pneumatologia e sinodalidade conforme a teologia dos Atos dos Apóstolos. A análise se propõe demonstrar que para o autor dos Atos a Igreja é “sínodo”, desencadeado e conservado pela ação direta do Espírito. Assim sendo, em primeiro lugar apresenta-se, em linhas gerais, o lugar da pneumatologia no referido livro. Passa-se, depois, à sumarização dos derramamentos do Espírito no decorrer da narrativa na qualidade de ação promotora da comunhão, ambiente vital da sinodalidade. Na terceira parte a abordagem concentra-se sobre o caráter sinodal da assembleia de Jerusalém, narrada em At 15. Ponto de inflexão no panorama geral da obra, a assembleia de Jerusalém, de certo modo, define os destinos da evangelização que haveria de plasmar a identidade do cristianismo mediterrâneo. Portanto, alinhavando a análise, a quarta seção discorre acerca do lugar dado ao Espírito na condução da missão. É, com efeito, a missão o objetivo coeso procurado pelo alcance sinodal da eclesiologia lucana naturalmente coextensiva à pneumatologia.
TEOLOGIA PROTESTANTE DAS RELIGIÕES: UMA PROPOSTA TEOLÓGICA EM PERSPECTIVA LATINO-AMERICANA
Authors: Veliq Fabrício
Published: October 2022

O livro, lançado no ano de 2020, é fruto de tese doutoral defendida na UMESP, dentro do Programa de Doutorado do curso de Ciências da Religião. O autor, motivado pela pouca produção a respeito de estudos protestantes dentro da América Latina que tenta dialogar com outras expressões religiosas do continente, bem como pelo fato de que prevaleceu no protestantismo da América Latina uma postura fundamentalista e conservadora, quer propor uma teologia protestante ecumênica das religiões em perspectiva latino-americana, a qual chama de TEOPELAR. Seu intuito é que tal proposta possa dialogar com as religiões presentes no continente, tendo em conta suas premissas culturais e teológicas. Deseja fugir das posturas teológicas que se colocam como única alternativa quando do contato destas com as religiões de matrizes africanas e ameríndias na América Latina. Como aporte teológico, o autor parte da teologia trinitária de Jürgen Moltmann, conhecidamente marcada pela abertura e pelo seu caráter social. Propõe a abertura como categoria hermenêutica em seu trabalho.
UMA ÁRDUA LETRA: AS TENSÕES, AS NEGOCIAÇÕES E O IMPACTO DO MOMENTO HISTÓRICO NA REDAÇÃO DA DECLARAÇÃO NOSTRA AETATE
Authors: Wolff Apolloni Rodrigo , Usarski Frank
Published: October 2022

Neste artigo, os autores se propõem a historiar o processo redacional da Declaração “Nostra Aetate”, um dos documentos resultantes do Concílio Vaticano II que tem grande importância em relação ao posicionamento da Igreja face às outras religiões e, de modo especial, ao judaísmo. Ao longo do texto, buscou-se identificar o processo de construção do documento, as negociações, idas, vindas, pressões, ameaças e protagonistas, dentre os quais se contam os papas João XXII e Paulo VI, o cardeal Augustin Bea e sua equipe, especialistas religiosos, políticos do Oriente Médio e católicos conservadores que se posicionaram contra as mudanças.
O CONCÍLIO VATICANO II E AS INOVAÇÕES PARA OS ESTUDOS BÍBLICOS NA AMÉRICA LATINA
Authors: Correia Júnior João Luiz
Published: October 2022

O artigo apresenta estudos, baseados em bibliografia apropriada, sobre a recepção do Concílio Vaticano II no Brasil, no que tange especificamente aos avanços registrados na pesquisa bíblica. Reconhece-se a importância da Constituição Dogmática Dei Verbum sobre a Revelação Divina para a exegese e hermenêutica da Sagrada Escritura. Ressaltam-se as inovações registradas na área dos estudos bíblico-teológicos na América Latina, destacando-se a grande contribuição de mulheres e homens que dedicaram suas vidas ao estudo e ministério da Bíblia. Algumas dessas pessoas são citadas por seus trabalhos relevantes realizados. Os resultados apontam que, apesar dos avanços do neoconservadorismo fundamentalistas da atualidade, a pesquisa e o ensino bíblico continuam sendo realizados na academia e na vida da Igreja, à luz dos avanços possibilitados pelo Concílio Vaticano II e por sua recepção na Igreja latino-americana.
A RELEVÂNCIA DA GAUDIUM ET SPES NOS 60 ANOS DO INÍCIO DO CONCÍLIO ECUMÊNICO VATICANO II
Authors: Campos Fernando Rui
Published: October 2022

Quando estamos a celebrar os 60 anos do Concílio Ecumênico Vaticano II, falar dos documentos conciliares, como seja, a Gaudium et Spes, convém perceber até que ponto este documento foi importante para as mudanças que se operaram após este acontecimento para a Igreja Católica e para o mundo, que foi o Concílio Vaticano II. O mundo tinha saído de uma Guerra fratricida há pouco tempo, era necessário reconstruir a Europa e o mundo. Os desafios sociais, para os quais eram necessárias respostas urgentes, a Igreja Católica era desafiada a responder aos problemas da pobreza, ou seja, enfatizar a Doutrina Social da Igreja. A América Latina, enfrentava sérios desafios, no que diz respeito aos problemas sociais e, também aqui, a Igreja Católica sentiu-se interpelada a dar respostas. A promoção do ecumenismo e do diálogo inter-religioso foi uma das iniciativas do Concílio.
A produção do espaço urbano em cidades médias a partir das novas demandas de classe média – a importância de garagens, suítes e dormitórios de apartamentos em Chapecó (SC)
Authors: Tischer Wellington , González Marco Aurélio Stumpf
Published: October 2022

O trabalho apresenta um modelo de preços hedônicos de apartamentos de classe média no município de Chapecó (SC), localizado na Região Sul do Brasil. Utilizou-se o método comparativo de dados de mercado como fontes de preços de imóveis pelos agentes imobiliários e, por meio de análise de regressão linear múltipla, foi elaborada a equação de preço que leva em consideração a área privativa, número de vagas de garagem, padrão de acabamentos e localização do imóvel. Discute-se a interpretação da inferência estatística do número de vagas de garagem e a variável independente localização e a produção do espaço urbano em uma cidade média. Isso pode estar relacionado com o recebimento de novos investimentos públicos e privados na periferia e promoção da verticalização de bairros pericentrais. Discute-se também, a característica do consumo da classe média a partir da compartimentação dos imóveis com relação aos dormitórios e suítes da amostra analisada. Como consideração finais, infere-se que a variável número de dormitórios, número de suítes têm-se demonstrado pouco explicativa e que área privativa e padrão de acabamentos têm maior relevância no contexto estudado.
Aplicações, propriedades e influência da cura de argamassas estabilizadas fornecidas em Concórdia - SC
Authors: Pertile Girlaine Weissheimer , Hentges Tatiane Isabel
Published: October 2022

Ainda ainda não foram desenvolvidas normas brasileiras que padronizem a execução, aplicação e controle tecnológico de argamassas estabilizadas, havendo apenas orientações e cuidados provindos dos fabricantes. Além disso, há preocupação sobre a aplicação de argamassa estabilizada em fachadas devido a exposição, pois o sistema está sujeito a pressões ambientais estáticas e dinâmicas que contribuem para abertura de fissuras, facilitando a entrada de água e agentes agressivos. Dentro deste contexto, este trabalho objetivou avaliar argamassas estabilizadas fornecidas na cidade de Concórdia, SC. Para isso, iniciou-se com um questionário aos trabalhadores que aplicam a argamassa em obra. Então, analisou-se em laboratório as propriedades no estado fresco e endurecido das argamassas. Por fim, foi realizado comparativo da execução de cura na argamassa endurecida. Os resultados mostraram que as duas argamassas em estudo apresentaram alta retenção de água, o que pode ter influenciado na baixa resistência de aderência à tração da argamassa B, além disso, a cura por aspersão de água também reduziu a resistência de aderência à tração aos 28 dias das duas argamassas em estudo. E ainda, a cura submersa aumentou a resistência à compressão e à tração na flexão da argamassa A, no entanto, houve uma redução dessas propriedades para a argamassa B. Em relação as aplicações e procedimentos realizados por empresas participantes da pesquisa, os resultados mostraram que argamassa com tempo de estabilização de 36 e 48h são as mais utilizadas, que a maioria das aplicações é para assentamento, revestimento interno e externo de alvenarias, e que 92% das empresas não realizam cura em argamassas. Dessa forma, pôde-se concluir que não há um padrão de desempenho nas argamassas das duas empresas fornecedoras da cidade, demonstrando a importância do desenvolvimento de normas específicas para argamassas estabilizadas. Além disso, a redução nas propriedades físicas das amostras em que foi realizada cura pode demonstrar uma estratégia de dosagem, por parte das empresas, que prevê a não realização de cura no canteiro de obras.
La investigación en Ciencias Médicas en la Universidad de Cuenca en los años 20 del siglo XX
Authors: Achig-Balarezo David
Published: October 2022

Editorial que analiza los años 20 del siglo XX en el mundo, Ecuador y Cuenca para describir las monografías de las tesis de esta década.
Quality analysis of the spacecraft foil electric heater meander manufactured using laser radiation
Authors: Vyatlev P.A. , Shemanov A.G. , Gorny S.G. , Yudin K.V. , Grigoriev P.S. , Mishin Yu.N.
Published: October 2022

The article presents a brief review of the photolithographic technology features used in manufacture of foil electric heaters for spacecraft. Potential advantages of laser technology for the foil electric heater formation are demonstrated. Using laser radiation, a full-fledged meander was manufactured from constantan foil on flexible substrate of aramid fabric impregnated with the EP-730 varnish as a blank for a foil electric heater of the spacecraft thermal control system. The degree of constantan evaporation between the current conductive tracks, as well as integrity and dielectric properties of the substrate, were evaluated. Results of the obtained samples study by the methods of spectral analysis, visual and optical control and measurement of the insulation resistance are provided. Conclusions present an assessment of advantages in using laser processing in the heating element formation, namely, reduction in the number of technological operations, decrease in labor intensity, increase in accuracy of the design geometry and improvement in the personnel labor protection conditions.
Szkic do portretu Witolda Staniewicza, profesora ekonomiki rolnej i ministra reform rolnych. Działalność naukowa, dydaktyczna i organizacyjna w latach 1921–1939
Authors: Łapa Małgorzata
Published: October 2022

Witold Staniewicz (1887–1966) to urodzony i mieszkający w Wilnie w okresie Drugiej Rzeczypospolitej naukowiec, polityk i działacz społeczny. Był profesorem Uniwersytetu Stefana Batorego w Wilnie, jego rektorem i prodziekanem Wydziału Rolniczego. Zainteresowania naukowe Staniewicza obejmowały: teorię polityki agrarnej i znaczenie rolnictwa w gospodarce narodowej, ekonomikę rolną, ekonomikę społeczną, historię rolnictwa i studiów rolniczych, problemy regionalnych uwarunkowań gospodarczych Wileńszczyzny oraz politykę deflacyjną. Artykuł podsumowuje aktualny stan wiedzy o Witoldzie Staniewiczu i przedstawia jego działalność naukową, dydaktyczną i organizacyjną w latach 1921–1939.
Attitudes of physical education teachers in Jordan towards the use of the Internet in the educational process
Authors: Jawarneh Randa Saleh , AL-Momani Mohammad Omar
Published: October 2022

The study aimed to identify the attitudes of physical education teachers in Jordan towards Internet use in teaching-learning process; where the descriptive approach was used in addition to the use of the questionnaire as a tool for the study which has been applied to the study sample made up of 328 teachers and educator and that in class in the second academic year school 2021–2022. The study, after carrying out the necessary statistical treatment, concluded: The presence of positive attitudes among teachers towards the use of the Internet in the educational process. There is a disparity in the use of the Internet in the educational process.
 
Keywords: Internet, the educational process, physical education subject, physical education teachers;
ANALYSIS OF THE EFFECT OF ISTIGHFAR DHIKR TO ADOLESCENT ANXIETY AT BETA WAVE ACTIVITY USING ELECTROENCEPHALOGRAM (EEG) EXAMINATION
Authors: Tasyakuranti Alvania Nabila , Sumarti Heni , Kusuma Hamdan Hadi , Istikomah Istikomah , Prastyo Irman Said
Published: October 2022

Information related to deviants in the near future is often the case by a group of adolescents. Behavior that deviates from anxiety because of a problem in daily life. One way that is taught by Islam by listed in the Qur'an and hadith to reduce anxiety in a person is to do istighfar dhikr. Knowing the beta brain wave activity in anxiety and istighfar dhikr condition can be done using an EEG (Electroencephalogram). Beta waves are brain waves that are detected when a person feels anxious. Beta wave measurement method is calculated based on peaks or troughs per second on the beta signal type frequency (13-30Hz). The method in this research is an experiment with quantitative data collection. The sample used in this study were 8 students in Universitas Islam Negeri Walisongo Semarang with an age range of 20-23 years. The data analysis technique used is bivariate with Paired T-test. The results showed that the average beta wave in anxiety condition was 14.213 Hz and istighfar dhikr was 13.085 Hz. The result of the Paired t-test showed that p = 0.002 (p 0.05) indicating that the decrease in beta waves in the brain is very significant. It shows that istighfar dhikr can reduce anxiety in adolescents.
Pre-service EFL Teachers as Future Professionals and Researchers
Authors: ATAK DAMAR Ebru , SALI Pınar
Published: October 2022

This paper reports on the preliminary findings of a larger qualitative and quantitative research study which attempted to unearth pre-service English as a foreign language (EFL) teachers’ perceptions of educational research and their own research experiences in their research methodology courses. The participants were 85 fourth-year pre-service EFL teachers who had already completed their compulsory ‘Research Methodology’ and ‘ELT Methodology’ courses in a large state university in Turkey. Data presented in this paper were collected by means of a questionnaire which was developed on the basis of a detailed literature review and the iterative discussions of the questionnaire items by the authors. For each survey item, frequency distributions and means were calculated. The findings revealed that EFL pre-service teachers held positive views about the concept of research and their own research experiences in general. Notwithstanding these positive views, they reported rather lower levels of certainty in relation to the role of research-oriented thinking in their lives, their confidence in themselves as researchers and in their research-related work, changing their research plans and revisiting key issues in their research, their feelings of satisfaction in doing research, the value of their work, and the possibility of their future research accomplishments.
Contratos internacionales regulados por Directivas UE sectoriales (Derecho Internacional privado)
Authors: Aguilar Grieder Hilda
Published: October 2022

El presente estudio analiza los problemas de Derecho aplicable que se plantean en los contratos internacionales objeto de regulación por Directivas europeas sectoriales; siendo éste un tema clave del Derecho internacional privado de la Unión Europea en materia contractual.
La desjudicialización del divorcio en la Unión Europea y su impacto en los Reglamentos europeos
Authors: Jiménez Blanco Pilar
Published: October 2022

La progresiva aparición de divorcios no judiciales en la UE tiene un impacto directo en los Reglamentos europeos sobre familia. En particular, el Reglamento (UE) nº 2019/1111 regula, por primera vez, el reconocimiento de acuerdos privados registrados, equiparándolo en su tratamiento a las resoluciones judiciales. Con ello, se simplifica el reconocimiento, pero se abren dudas respecto a la aplicación de los criterios de competencia y respecto a la ley aplicable. Es necesario evitar el turismo de divorcios y garantizar el control sobre el consentimiento. Al mismo tiempo, se examinan los problemas de coordinación con el resto de Reglamentos, en relación con la eficacia respecto a la responsabilidad parental, los alimentos o el régimen económico matrimonial. El riesgo vendrá por los divorcios con eficacia transfronteriza solo en parte.
El Reglamento (CE) 2019/1111
Authors: Guzmán Peces Montserrat
Published: October 2022

El presente trabajo se centra en el análisis de las principales novedades del Reglamento
2019/1111 (RBII ter) en relación con el Reglamento 2201/2003 (RBII bis) y la relación existente con los otros dos Convenios de la Conferencia de la Haya, el de 1980 y el de 1996. Para ello, se explica el ámbito de eficacia material, centrándose en las nociones de guarda y custodia y la responsabilidad parental en los diferentes instrumentos. Además, al hilo de la introducción de nuevos criterios de competencia en el RBII ter se respecto del CH 1996, se explica la relación existente con el Reglamento y, la posibilidad de elección de un foro de terceros Estados como preceptúa el art. 97 del RBII ter. Respecto del CH de 1980 se analiza la incorporación y la puesta en marcha de los instrumentos de cooperación de autoridades y la disposición del art. 96 del RBII ter. Para finalizar, se reflexiona sobre los avances en este ámbito y, el recurso a la mediación cuando se ha producido una sustracción ilícita de menores.
KOCA KARI İLE ÖMER MANZUM HİKÂYESİNDE ESTETİK BİR UNSUR OLARAK RİTMİK OLUŞUMUN NİYETİ GÖRÜNÜR KILMASI
Authors: TARAKÇI Gülsüm
Published: October 2022

Bir metnin kurmaca vasfı taşımasında önemli bir unsur olan ritim, anlatının bütünlüğünü ve bu bütünlük içinde ahenkli akışını sağlayan estetik bir ögedir. Edebî bir metnin ‘Neyi, nasıl anlatıyor?’ sorusuna verilecek bir cevabın da ritmik oluşumla ilgili olduğunu söylemek yanlış olmaz. Belli bir niyet etrafında oluşturulan edebî eserde, anlatının yapısal unsurları olan olay, kişi, zaman ve mekân, anlatıcının tasarrufuna bağlı olarak belirli oranlarda metinde yer alırlar. Bu tasarruf, metnin niyetiyle yakından ilgilidir. Kurmaca dünyada gerçek dünyadaki gibi her şeyin anlatılması mümkün değildir. Anlatıda kimi zaman bazı olaylar detaylı bir şekilde anlatılırken bazı olaylar üzerinde ise fazla durulmadan özetle geçilir. Diğer bir ifadeyle anlatıcı, metnin niyetine bağlı olarak anlatması gerekeni istediği sürede, istediği sıklıkta ve istediği düzende anlatır. Ayrıca bu anlatış, okuru adeta kurgunun içine çekerek onda güzellik duygusu uyandıracak şekilde etkili de olmalıdır. Bu etki, bir anlatıda ritmik oluşumla sağlanabilir. Kronolojik dizilenmeden farklılık gösteren anlatı metinlerinde, zamanda ileri ve geriye kırılmalar, sahneleme, özetleme, eksilti ve duraklama teknikleri, yapılan tekrarlar bir anlatıda ritmik oluşumu sağlayan unsurlardır. Bu çalışmada anlatma esasına bağlı edebî metin türlerinden birisi olan Mehmet Akif Ersoy’un Koca Karı ile Ömer adlı manzum hikâyesinde ritmik oluşumun nasıl temin edildiği tespit edilmeye ve estetik bir unsur olarak ritmik oluşumun metnin niyetini nasıl görünür kıldığı belirlenmeye çalışılacaktır.
Towards extracellular vesicle delivery systems for tissue regeneration: material design at the molecular level
Authors: Chen Ao , Tian Hengli , Yang Nana , Zhang Zhijun , Yang Guo-Yuan , Cui Wenguo , Tang Yaohui
Published: October 2022

The discovery and development of extracellular vesicles in tissue engineering have shown great potential for tissue regenerative therapies. However, their vesicle nature requires dosage-dependent administration and efficient interactions with recipient cells. Researchers have resorted to biomaterials for localized and sustained delivery of extracellular vesicles to the targeted cells, but not much emphasis has been paid on the design of the materials, which deeply impacts their molecular interactions with the loaded extracellular vesicles and subsequent delivery. Therefore, we present in this review a comprehensive survey of extracellular vesicle delivery systems from the viewpoint of material design at the molecular level. We start with general requirements of the materials and delve into different properties of delivery systems as a result of different designs, from material selections to processing strategies. Based on these differences, we analyzed the performance of extracellular vesicle delivery and tissue regeneration in representative studies. In light of the current missing links within the relationship of material structures, physicochemical properties and delivery performances, we provide perspectives on the interactions of materials and extracellular vesicles and the possible extension of materials. This review aims to be a strategic enlightenment for the future design of extracellular vesicle delivery systems to facilitate their translation from basic science to clinical applications.
The Dirac Fermion of a Monopole Pair (MP) Model
Authors: Yuguru Samuel
Published: October 2022

The electron of magnetic spin −1/2 is a Dirac fermion of a complex four-component spinor field. Though this is effectively addressed by relativistic quantum field theory, an intuitive form of the fermion still remains lacking. In this novel undertaking, the fermion is examined within the boundary posed by a recently proposed MP model of a hydrogen atom into 4D space-time. Such unorthodox process somehow is able to remarkably unveil the four-component spinor of non-abelian in both Euclidean and Minkowski space-times. Supplemented by several postulates, the relativistic and non-relativistic applications of the magnetic spin property are explored from an alternative perspective. The outcomes have important implications towards an alternative interpretation of quantum electrodynamics and a probable quantum universe, where quantum mechanics and general relativity are expected to merge. Such findings could pave the paths for future pursuits of physics beyond the Standard Model and they warrant further investigations.
Atmospheric Altitude Effects on Optical Channel performance
Authors: Mazher Wamidh
Published: October 2022

in this paper, the optical channel performance with respect to varying scintillation index parameters is studied. Where different channel effects are studied and analyzed. In free-space optical (FSO) communication, the major drawback of the optical communication system is the atmospheric turbulence (AT). This effect is nonlinear with optical channel altitude being changed. Therefore, the power margenal (PM) required for such a channel is also inconstant respectively. In this thesis, we analyze AT effect on the optical channel with different altitudes. Such that we found the difference in the range of PM required for such optical link distance. In our result, the Bit Error Rate (BER) VS. PM required is measured. The optical channel model is Log-Normal considered and the BER threshold BERth = 10-10 is taken.
A Quantitative Assessment of Rubrics Using a Soft Computing Approach
Authors: Bhattacharyya Siddhartha , De Sourav , Mrsic Leo , Pan Indrajit , Muhammad Khan , Mukherjee Anirban , Konar Debanjan
Published: October 2022

This study aims to elucidate a soft computing approach for quantitative assessment of the scoring grade or rubrics for students in an outcome based education system. The intended approach resorts to a fuzzy membership based assessment of the different parameters of the scoring system, thereby yielding a novel and humanly assessment technique. The selection of the membership functions is based on the human behavior so as to make a realistic representation of the scoring strategy. The novelty of the proposed strategy lies in assigning fuzzy membership based weighted scores instead of simply assigning score bands to rubric categories, as is performed in normal rubrics based assessment. Comparative results demonstrated on a case study of Indian education scenario reveal the effectiveness of the proposed strategy over other fuzzy membership and normal rubrics based assessment procedures.
Improvement, Standardization, and Validation of A Novel Genomic DNA Extraction Method for Human Breastmilk
Authors: Alemán-Duarte Mario Iván , Aguilar-Uscanga Blanca Rosa , García-Robles Guadalupe , Ramírez-Salazar Felipe de Jesús , Benítez-García Israel , Balcázar-López Edgar , Solís-Pacheco Josué Raymundo
Published: October 2022

Recent advances in DNA sequencing technology have shown that the human milk microbiota of healthy women varies substantially. The gDNA extraction method may influence the observed variation, biasing the microbiological reconstruction after all. In this study, a genomic DNA extraction method for DNA isolation from human milk samples was standardized and compared with commercial and standard hose make methods. Spectrophotometric measurements, gel electrophoresis, and PCR amplifications were used as criteria for evaluating the quantity, quality, and functionality of the extracted DNA. Furthermore, the standardized method of extracting gDNA from human milk was evaluated for its ability to isolate functional DNA from gram-positive, and gram-negative bacteria and fungi, to improve the reconstruction of microbiological profiles. The novel DNA extraction method increased the quantity and quality of the gDNA extracted compared with commercial and standard house-make protocols. This method even allowed PCR amplification of the V3-V4 regions of the 16S ribosomal gene in all samples, and the ITS-1 region of the fungal 18S ribosomal gene in 95 % of the samples as well. It is concluded that the proposed method provides better performance for the extraction of gDNA from complex samples such as human milk.
Cardiac Magnetic Resonance in Fabry Disease: Morphological, Functional and Tissue Features
Authors: Aquaro Giovanni Donato , De gori Carmelo , Faggioni Lorenzo , Parisella Maria luisa , Aringhieri Giacomo , Cioni Dania , Lencioni Riccardo , Neri Emanuele
Published: October 2022

Fabry disease (FD) is a X-linked inheritable storage disease caused by deficiency of al-pha-galactosidase causing lysosomal overload of sphingolipids. FD cardiomyopathy is character-ized by left ventricular (LV) hypertrophy and should be considered in differential diagnosis with all the other causes of LV hypertrophy. An early diagnosis of FD is very important because the enzyme replacement therapy (ERT) may change the fate of patients by blocking both cardiac and systemic involvement and improving prognosis. Diagnosis may be relatively easy in young patients with the typical signs ans symptoms of FD, but in male patients with late onset of disease and in females, diagnosis may be very challenging. Morphological and functional aspects are not specific for FD, which cannot be diagnosed or excluded by echocardiography. Cardiac magnetic resonance (CMR) with tissue characterization capability, is the preferred technique for the differential diagnosis of LV hypertrophy. The finding of decreased myocardial T1 value in LV hypertrophy is very specific for FD. Late gadolinium enhancement (LGE) is found in late stage of disease but it is useful to predict the cardiac response to ERT and to stratify the prognosis.
Absolute Time, Length Expansion, Particle Mass Origins, Quantum Entanglement, Pauli Exclusion Principle and Higgs Boson on the 4-D Euclidean Space
Authors: Hwang Jae-Kwang
Published: October 2022

The absolute time and relative time are defined in terms of the 4-D Euclidean space. Our universe is the 3-D x1x2x3 quantized photon space which follows the absolute time simultaneity when the universe moves along the absolute time axis of ct. The length expansion of Dx = gDx0 is derived under the condition of the absolute time (ct) simultaneity. From the similarity between this length expansion of Dx = gDx0 and the energy increasing of E = gE0, it is assumed that the energy is proportional to the particle size of Dx. The extension of this assumption to the 4-D Euclidean space gives the new definition that the particle energy (E) is the 4-D volume. Then, the particle mass energy is defined as E= mc2 = cDtDV = gE0. The masses of the elementary particles are originated from the 4-D warped volume of the photon space because the particle is the warped photon space with the velocity of v < c. Therefore, the Higgs boson concept in the standard model (SM) is not needed in the present 3-D quantized space model (TQSM). The scalar boson with the spin of zero, photon with the spin of 1 and graviton with the spin of 2 are the two-boson states. Therefore, the observed Higgs boson is reinterpreted as the two-boson state of the scalar boson with the spin of zero. The cosmic muon observation and twin paradox are explained by using the absolute time and relative time. The relative time is the observed time in the twin paradox and cosmic muon observation. In the twin paradox, a person who travels the long distance is more aged than a person on the earth in terms of the relative time ages because of the space and time conversion effect (STCE effect) of the moving space distance (x). But twins are in the same ages in terms of the absolute time without STCE effect. The fast-moving cosmic muon has the expanded half-life from the time expansion of the relative time. Also, the quantum entanglement and Pauli exclusion principle are explained. The quantum base of the photon space line connects two entangled particles. Two particles and quantum base system is fluctuated along the absolute time axis by the time clicking when one particle is measured. Another particle is instantly selected by the time clicking. This is called as the quantum entanglement. The photons which are the flat photon space with the constant speed of c along the space axis and absolute time axis have the 4-D photon velocity of ceff = 20.5 c. Total 10-D Euclidean space including three 3-D quantized spaces and one absolute time axis is required for the electric charges (EC), lepton charges (CC) and color charges (CC) of the elementary particles. The 3-D photon space is very stiff along the absolute time (ct) axis and very soft along the space axes. The Coulomb force through the photons (2EM waves) of the space fluctuations is much stronger than the Gravitational force through the gravitons (G waves) of the time fluctuations between two electrons.
1.5T MR-Guided Daily-Adapted SBRT on Lymphnode Oligometastases from Prostate Cancer
Authors: Nicosia Luca , Trapani Giovanna , Rigo Michele , Fiorini Matilde , Giaj-Levra Niccolò , Mazzola Rosario , Pastorello Edoardo , Ricchetti Francesco , Alongi Filippo
Published: October 2022

Introduction: The aim of our study was to evaluate the efficacy and toxicity of a daily-adaptive MR-guided SBRT on 1.5 T MR-linac in patients affected by lymphnode oligometastases from PCa. Materials and Methods: The present study is a prospective observational study conducted in a single institution (protocol n°: MRI / LINAC n. 23748). Patients with oligometastatic lymphnodes from PCa treated with daily-adaptive MR-guided SBRT on 1.5T MR-linac were included in the study. Minimum required follow-up of 3 months after SBRT. Primary end-point was local progression-free survival (LPFS). Secondary end-points were: nodal progression-free survival (NPFS), and progression-free survival (PFS), and toxicity. Results: 118 lymphnode oligometastases from PCa were treated with daily-adaptive 1.5T MR-guided SBRT in 63 oligometastatic patients. 63.5% patients were oligoprogressive and 36.5% oligoprogressive. Two-year LPFS was 94.5%. Median NPFS was 22.3 months, and the 2-year NPFS was 46.5%. Having received hormone therapy before SBRT was correlated with lower NPFS at the multivariate analysis (1-y NPFS 87.1% versus 42.8%; p= 0.002 - HR 0.199, 95% CI 0.073-0.549). Furthermore, the oligorecurrent state during ADT was correlated with a lower NPFS than the oligoprogressive state. Median PFS was 10.3 months, the 2-year PFS was 32.4%. Patients treated with hormone therapy before SBRT had a significantly lower 1-year PFS the others (28% versus 70.4%; p= 0.01 - HR 0.259, 95% CI 0.117-0.574). No acute and late toxicities occurred during treatment. Conclusion: the present is the largest prospective study of 1.5T lymphnode SBRT on MR-linac in patients with PCa. Lymphnode SBRT by 1.5T MR-linac provides high local control rates with an excellent toxicity profile.
A Study on English Phonetic Acquisition from the Perspective of Transfer Theory
Authors: Yang Chenyu , Fu Xiaoqiu
Published: October 2022

English, as an international lingual Franca, has become one of the most widely-used languages in the world. Mastering English doesn't just mean getting information from all over the world; it also means communicating and expressing yourself with people from different cultural backgrounds. So far, EFL has received much attention in many counties. As an indispensable part of language acquisition, pronunciation learning should be valued at the beginning of foreign language study, for example, the kindergarten stage. This paper aims to illustrate the negative transfer of the mother tongue on English pronunciation acquisition from the segmental and suprasegmental aspects. Based on the studies and analysis, it hopes to inspire teachers to arouse awareness of the differences between English and Chinese pronunciation among learners, making students acquire native-like pronunciation actively and positively. It’s suggested that EFL learners can their pronunciation and intonation through practice.