bluuebunny/crossref_metadata_2025 huggingface dataset:
Introduction to the Special Issue: Successful Inclusion for Students With Disabilities Who Are Learning English
Authors: Spies Tracy G. , Cheatham Gregory A.
Published: March 2018

Students who are learning English is one of the fastest growing groups of students in U.S. public schools. Evidence suggests that students learning English are often placed in segregated special education classrooms seemingly contradicting the Individuals With Disabilities Education Act mandate for the education of students with disabilities to occur within the least restrictive environment including modifications and adaptations to the general curriculum. Successful inclusive practices for students with disabilities who are learning English highlight and build on the cultural, academic, and linguistic strengths students bring to the classroom. This special issue features a variety of articles focused on collaborative, inclusive practices that build on the cultural, academic, and linguistic strengths of students with disabilities who are learning English. The issue focuses on two themes: (a) instruction and support and (b) collaboration and partnerships.
Neonatal Macroglossia
Authors: Simmonds Jonathan C. , Patel Anju K. , Mildenhall Nicholas R. , Mader Nicholas S. , Scott Andrew R.
Published: March 2018

Objectives:

To examine the birth prevalence of congenital macroglossia and identify demographic variables and comorbidities that may influence length of stay and cost of care.

Study Design:

Retrospective cross-sectional study using the Kids’ Inpatient Database 2003, 2006, 2009, and 2012.

Methods:

Demographics were analyzed. Linear regression modeling and multivariate analyses were performed.

Results:

The birth prevalence of congenital macroglossia was 4.63/100 000 births. Patients were classified as isolated (n = 349, 48.1%) or syndromic (n = 377, 51.9%). A higher incidence of isolated macroglossia was seen in females (odds ratio, OR [95% confidence interval, 95% CI]: 1.93 [1.45-2.56] and African Americans (2.02 [1.41-2.88]). Length of stay was higher for syndromic patients than for nonsyndromic patients (22.6 days [18.6-26.6] vs 7.93 days [5.95-9.90], as were inpatient costs ($3619USD [$27 628-$44 754] vs $10 168USD [$6272-$14 064]. After accounting for gender, race, location, and socioeconomic status, the presence of macroglossia alone increased length of stay by 4.07 days (0.42-7.72 days) in nonsyndromic patients and 12.02 days (3.63-20.4 days) in syndromic patients. The cost of care increased by $6207USD ($576-$11 838) among nonsyndromic newborns and $17 205USD ($374-34 035) among syndromic patients.

Conclusion:

The birth prevalence of congenital isolated macroglossia appears to vary by sex and race. Prolonged length of stay and increased costs are associated with both isolated macroglossia and syndromic macroglossia, even after controlling for other syndromic comorbidities.
Sociodemographic Predictors of Missed Appointments Among Patients With Cleft Lip and Palate
Authors: Lynn Jeremy V. , Ranganathan Kavitha , Bageris Matthew H. , Hart-Johnson Tami , Buchman Steven R. , Blackwood R. Alexander
Published: March 2018

Objective:

To identify disparities in compliance of and care for patients with cleft lip and/or palate (CL/P) by determining the impact of sociodemographic variables on the rate of missed appointments and Child Protective Services (CPS) involvement.

Design:

A retrospective, noninterventional quality assessment and quality improvement study were designed.

Setting:

This institutional study was performed at the University of Michigan in Ann Arbor, Michigan.

Patients:

All patients born between January 1, 2011, and December 31, 2014, who underwent surgical CL/P repair, excluding those with fewer than 5 appointments (n = 178).

Main Outcome Measure:

The rate of missed appointments, calculated as the total number of no-show appointments divided by the total number of scheduled appointments. All appointments from CL/P diagnosis to data collection were considered, including those outside of plastic surgery.

Results:

The average patient was 4.5 years of age and had 49 total scheduled appointments. The overall rate of missed appointments was 9.6%, with 66.8% of patients missing at least 1 scheduled visit. Patients who were black ( P = .04), not affiliated with a religion ( P = .01), Medicaid users ( P = .01), from an unstable social background ( P = .01), or received need-based financial assistance ( P = .00) were significantly more likely to miss appointments. Child Protective Services was involved with 3.9% of patients.

Conclusions:

Disparities exist in attendance rates among patients with CL/P, and at-risk patient populations have been identified. The allocation of cleft care resources must be efficiently planned in order to enhance the quality of care for at-risk individuals.
Loss of Hope and Suicide Risk in Hungarian College Students
Authors: Chang Edward C. , Chang Olivia D. , Martos Tamás , Sallay Viola
Published: March 2018

We examined hope and family support as predictors of suicide risk (viz., anxious symptoms, depressive symptoms, and suicide ideation) in a sample of 502 Hungarian college students. Results of hierarchical regression analyses indicated that the inclusion of family support provided further incremental validity in predicting all three indices of suicide risk beyond the variance accounted for by hope. Consistent with the notion that family support might moderate the beneficial effects of hope on suicide risk, evidence for a significant Hope × Family Support interaction effect in predicting all three indices of suicide risk was found. Additionally, a significant interaction effect in predicting suicide ideation remained, even after controlling for psychological symptoms. Beyond the role of hope in predicting suicide risk in Hungarian college students, the present findings show how family support both additively and interactively represents a positive psychological resource that should be considered in understanding suicide risk among students.
Intravascular Large B-Cell Lymphoma Within a Thyroid Nodule: A Diagnostic Pitfall
Authors: Linnik Yevgeniy , Nicka Catherine , Lansigan Frederick , Loo Eric , Liu Xiaoying
Published: March 2018

Intravascular large B-cell lymphoma (IVLBCL) is a subtype of diffuse large B-cell lymphoma, where the neoplastic lymphoid proliferation resides predominantly within the lumens of blood vessels but with no or few circulating neoplastic cells in the peripheral circulation. Focal or subtle involvement in some cases can cause the diagnosis to be misinterpreted or even overlooked, delaying the initiation of appropriate treatment. Our report focuses on a 78-year-old woman with a progressively enlarging thyroid mass, verified by ultrasound. She underwent a hemithyroidectomy, and microscopic evaluation demonstrated nodular thyroid parenchyma with atypical large cells in an intravascular distribution pattern identified on high magnification. Thorough evaluation showed that the large intravascular cells were positive CD20, PAX-5, and Ki-67 by immunoperoxidase staining, which lead to the diagnosis of IVLBCL. This case emphasizes the subtle appearance of IVLBCL, which may be missed on low-power light microscopy, and the need for careful evaluation of thyroid resection specimens.
Treatment with platelet-rich plasma of surgically related dormant corneal ulcers
Authors: Alio Jorge L , Rodriguez Alejandra E , De Arriba Pablo , Gisbert Sandra , Abdelghany Ahmed A
Published: March 2018

Purpose:

To assess the effectiveness of autologous platelet-rich plasma for the treatment of dormant corneal ulcers secondary to corneal surgery and unresponsive to conventional treatment.

Setting:

VISSUM, Ophthalmology Institute of Alicante, Alicante, Spain.

Design:

Prospective nonrandomized, observational consecutive study.

Methods:

A total of 44 eyes of 28 patients with dormant corneal ulcers secondary to corneal surgery were included in a prospective study and treated with autologous platelet-rich plasma during 6 weeks. Wilcoxon signed-rank test was used to compare the effect of the treatment.

Results:

In all, 28 patients (65.1%) improved their visual acuity at least one line in Snellen chart, 26 (59.09%) had a decrease in the size of the ulcer or even a total closure, and 40 (90.9%) experienced an improvement in their symptoms. The results are also provided for the four groups of patients (keratoplasty, refractive surgery, cross-linking, and chronic postsurgical corneal edema).

Conclusion:

Platelet-rich plasma eye drops shows to be a good option for the treatment of dormant corneal ulcers secondary to corneal surgery.
Comparing capsular bag performance of a hydrophilic and a hydrophobic intraocular lens: A randomised two-centre study
Authors: Koshy John , Hirnschall Nino , Vyas Ashok Kumar V , Narendran R , Crnej Alja , Gangwani Vinod , Nishi Yutaro , Maurino Vincenzo , Findl Oliver
Published: March 2018

Purpose:

To evaluate the capsular bag performance and posterior capsule opacification development of two intraocular lenses differing in material and design.

Methods:

This study included patients who were scheduled for cataract surgery and compared a hydrophilic intraocular lens (Super flex® intraocular lens; Rayner Surgical, Worthing, UK) with a hydrophobic intraocular lens (AcrySof® SA60AT; Alcon, Fort Worth, TX, USA). Follow-ups were performed 1 month and 2 years after cataract surgery, including a slit lamp examination and retroillumination images.

Results:

In total, 80 eyes of 80 patients were recruited. At the 1-month follow-up, 6 of 39 cases had a gap between the posterior lens capsule and intraocular lens (1 case in the hydrophilic intraocular lens group and 5 cases in the hydrophobic intraocular lens group; p = 0.348). Objective and subjective posterior capsule opacification scoring showed no statistically significant difference between both groups (p = 0.123).

Conclusion:

Both intraocular lens showed a good capsular bag performance and a relatively low posterior capsule opacification development within the first 2 years after surgery.
Comparative evaluation of Scheimpflug tomography parameters between thin non-keratoconic, subclinical keratoconic, and mild keratoconic corneas
Authors: Huseynli Samira , Salgado-Borges José , Alio Jorge L
Published: March 2018

Purpose:

To evaluate and compare the topographic and topometric parameters, thickness profile data, and data from enhanced elevation maps of thin non-keratoconic, subclinical keratoconic, and mild keratoconic corneas with the Pentacam Scheimpflug corneal tomography and to study the usefulness of different parameters to differentiate keratoconus from topographically normal thin corneas.

Methods:

The study included 30 eyes with subclinical keratoconus, 30 eyes with mild-stage keratoconus, and 54 healthy eyes with minimal pachymetry ≤500 µm, with a mean age of 21.19 ± 2.97, 21.75 ± 1.93, and 21.5 ± 2.95 years, respectively. The area under the receiver operating characteristic curves was used to analyze the diagnostic significance of the Pentacam parameters.

Results:

The anterior and posterior corneal elevations, pachymetric progression, the percentage of thickness increase measurements, overall D value, and topometric indices were statistically significantly higher in subclinical and mild keratoconic corneas than in normal eyes with thin cornea (p < 0.05). All these parameters had sufficient strength (area under the receiver operating characteristic curves >0.90) to differentiate clinical keratoconus. Posterior elevation showed the excellent area under the receiver operating characteristic curves with 100% sensitivity and 100% specificity for this purpose. However, among all parameters studied, the anterior elevation (0.935) showed the excellent area under the receiver operating characteristic curves to differentiate subclinical keratoconus, followed by posterior elevation (0.897), index of height decentration (0.887), and D value (0.882).

Conclusion:

The parameters derived from the Scheimpflug device, such as corneal elevations and overall D value, can effectively differentiate subclinical and clinical keratoconus from non-keratoconic thin cornea eyes. However, the specificity levels of these parameters were relatively limited in the diagnosis of subclinical keratoconus.
Positive thinking elevates tolerance: Experimental effects of happiness on adolescents’ attitudes toward asylum seekers
Authors: Tenenbaum Harriet R , Capelos Tereza , Lorimer Jessica , Stocks Thomas
Published: March 2018

Inducing emotional reactions toward social groups can influence individuals’ political tolerance. This study examines the influence of incidental fear and happiness on adolescents’ tolerant attitudes and feelings toward young Muslim asylum seekers. In our experiment, 219 16- to 21-year-olds completed measures of prejudicial attitudes. After being induced to feel happiness, fear, or no emotion (control), participants reported their tolerant attitudes and feelings toward asylum-seeking young people. Participants assigned to the happiness condition demonstrated more tolerant attitudes toward asylum-seeking young people than did those assigned to the fear or control conditions. Participants in the control condition did not differ from participants in the fear condition. The participants in the happiness condition also had more positive feelings toward asylum-seeking young people than did participants in the control condition. The findings suggest that one way to increase positive attitudes toward asylum-seeking young people is to improve general emotional state.
Mental health of unaccompanied asylum-seeking adolescents previously held in British detention centres
Authors: Ehntholt Kimberly A , Trickey David , Harris Hendriks Jean , Chambers Hannah , Scott Mark , Yule William
Published: March 2018

Aim:

To investigate whether the mental health of unaccompanied asylum-seeking children (UASC) was negatively affected by having their ages disputed and being detained.

Method:

Participants within this cross-sectional study were 35 UASC, aged between 13 and 17 when they were detained. Some years later, a team of child mental health professionals interviewed them to assess their current mental health and to determine, as far as possible, the impact that having their age disputed and being detained may have had on their mental health. The Structured Clinical Interview for DSM-IV (SCID-IV), Reactions of Adolescents to Traumatic Stress (RATS), Stressful Life Events (SLE) and Detention Experiences Checklist–UK version (DEC-UK) were administered.

Results:

The vast majority of UASC reported being negatively affected. Based on diagnostic interviews using the SCID-IV, self-report measures and contemporaneous records, the professionals reported a diagnosis of post-traumatic stress disorder (PTSD) developing in 29% ( n = 10), PTSD exacerbated in 51% ( n = 18), major depressive disorder (MDD) developing in 23% ( n = 8) and MDD exacerbated in 40% ( n = 14). A total of 3 years post-detention, 89% ( n = 31) met diagnostic criteria for psychiatric disorders and reported high PTSD symptoms.

Conclusion:

There was a high prevalence of psychiatric disorder. The additional stress of age dispute procedures and detention was judged to have been harmful.
A longitudinal study of primary school EFL learning motivation in CLIL and non-CLIL settings
Authors: Pladevall-Ballester Elisabet
Published: March 2018

Content and language integrated learning (CLIL) is often introduced in school settings in an attempt to increase exposure to the foreign language (FL) and promote motivation and positive language attitudes. The present study examines how language learning motivation develops over the course of two academic years in two types of instruction setting (CLIL and non-CLIL) with equal but low exposure to the FL and in two types of CLIL subject (science and arts and crafts). Data were collected from four primary schools in fifth and sixth grades by means of a motivation questionnaire. Differences between groups are observable in relation to the second language (L2) learning experience dimension of motivation in favour of the CLIL learners, who increased their motivation over time. Type of CLIL subject was found to be relevant also only in relation to the L2 learning experience dimension of motivation. Even in low exposure contexts, FL motivation is promoted and maintained over time by adding CLIL to the language experience of young learners.
Prevalence and trends of overweight and obesity in older adults from 10 European countries from 2005 to 2013
Authors: Peralta Miguel , Ramos Madalena , Lipert Anna , Martins João , Marques Adilson
Published: March 2018

Aims: Overweight and obesity are clinical public-health concerns worldwide. Amongst older adults, the prevalence of overweight and obesity is considered high. The purpose of this study was to provide current data regarding the prevalence and trends of overweight and obesity of adults from 2005 to 2013 in 10 European countries. Methods: The data used in the present study were derived from the first, second, fourth and fifth waves of the Survey of Health, Ageing and Retirement in Europe. The present study includes individuals aged ⩾50 years from 10 European countries. Body mass index (BMI) was calculated from self-reported height and weight (kg/m2). Results: The general prevalence of overweight (BMI ⩾25 kg/m2) was slightly above 60% and remained stable between 2005 (60.1%, 95% confidence interval (CI): 59.3–60.9%) and 2013 (60.3%, 95% CI: 59.7–60.9%). On the other hand, the prevalence of obesity (BMI ⩾30 kg/m2) increased significantly (1.6 points, 95% CI: 0.7–2.6) from 17.5% in 2005 to 19.2% in 2013. Although the prevalence of obesity increased in most countries, the only significant increase was observed in Germany (5.8 points, 95% CI: 1.8–9.9). Spain was the only country where the prevalence of obesity decreased significantly (−4.7 points, 95% CI: −8.8 to −0.5). Sex and age differences are reported. Conclusions: Although the prevalence of overweight was stable, the prevalence of obesity rose. Based on the data currently available for Europe, the prevalence of obesity in European older adults has already reached epidemic proportions, which reinforces the need for the development of effective healthy lifestyle programs.
Motivation: The missing driver for theorizing about resource integration
Authors: Findsrud Rolf , Tronvoll Bård , Edvardsson Bo
Published: March 2018

Resource integration is vital to value co-creation. However, most research focuses on competencies as enablers of resource integration and the social aspects that guide them. Based on a literature review of resource integration and motivation theories, this article proposes including motivation as a driver of resource integration and integrating concepts from motivation theories into the resource integration process. This approach extends the understanding and conceptualization of actors’ resource integration processes, such that motivation determines the direction, intensity, and persistence of effort. When they engage in behavioral and cognitive activities, actors interact with resources, which informs the actors and influences their competences and motivation. Accordingly, motivation is central for a clear understanding of the psychological mechanisms of resource integration processes, as motivation expands the explanatory power of sociological factors by including intensity and persistence.
The role of the non-human in relations of care: baby things
Authors: Waight Emma , Boyer Kate
Published: March 2018

In this article, we argue that the non-human plays a vital role within networks of care. We do this through a consideration of the forms of work done by baby things in the giving and receiving of young-child care. We extend existing understandings of human–non-human relations by arguing that beyond the work of warming babies’ bodies and providing comfort, baby things function within care assemblages as both a means and a metric of parental care. Within the consumption literature, the work of home provisioning (typically undertaken by mothers) has been cast as an expression of love for others. We build on this by exploring the forms of participation and ‘caring capacities’ of matter itself – objects such as blankets, soft-toys and pacifiers – in the caring-for of babies and young children. We attend to the flows and stoppages of baby things across networks of early childhood caregiving to consider what these patterns of movement suggest about how such artefacts participate within relations of care, and how they are used as a means to reflect on the care practices of others. Analysis is based on 30 interviews with mothers and ethnographic and survey work at 14 children’s clothing exchanges in different parts of England and Scotland. Drawing on scholarship from the New Materialism as well as Mary Douglas’s conceptual work on dirt and cleanliness,1 we advance conceptual work within and beyond Cultural Geography by arguing that analytical attention to the role of the more than human leads to richer and more nuanced understandings of how care relations work.
Sexual Responses Are Facilitated by High-Order Contextual Cues in Females but Not in Males
Authors: Ponseti Jorge , Dähnke Kim , Fischermeier Leona , Gerwinn Hannah , Kluth Amelie , Müller Jens , Vogel Susanne , Stirn Aglaja
Published: March 2018

Sexual responses are thought to be controlled by a brain module called the sexual module. Sexual strategies of males and females vary to a great extent, and sexual responses of males and females may be affected by their sexual strategies. However, the current view of the sexual module is that of a unisex module. This might be questionable since brain modules are defined as evolved cognitive mechanisms to solve adaptive problems which are different for males and females. We hypothesize that the sexual module responds differently in the presence of complex (high-order) contextual cues that are related to gender-dimorphic sexual strategies in males and females.

We conducted a priming experiment in which stimuli related to sexual strategies were disentangled from their sexual meaning. Nonsexual priming pictures related to either economic resources or social interactions preceded a sexual-target picture in order to test whether the primes were able to modulate the subjective sexual response to the sexual target. In a control condition, priming pictures without relation to mating preferences but with similar emotional impact were presented. In males, sexual responses were similar in the experimental and control conditions. In females, however, primes related to economic resources or social interactions modulated sexual arousal significantly more than the control primes. Our findings suggest that brain modules dedicated to process the experimental primes were functionally connected with the sexual module in females more than in males, making females’ sexual responses more prone to the impact of high-order cultural cues than males’ sexual responses. A gender-dimorphic connectivity of the sexual module may be the way in which gender-dimorphic sexual strategies are implemented in the human mind.
Neurofeedback-Based Enhancement of Single-Trial Auditory Evoked Potentials: Treatment of Auditory Verbal Hallucinations in Schizophrenia
Authors: Rieger Kathryn , Rarra Marie-Helene , Diaz Hernandez Laura , Hubl Daniela , Koenig Thomas
Published: March 2018

Auditory verbal hallucinations depend on a broad neurobiological network ranging from the auditory system to language as well as memory-related processes. As part of this, the auditory N100 event-related potential (ERP) component is attenuated in patients with schizophrenia, with stronger attenuation occurring during auditory verbal hallucinations. Changes in the N100 component assumingly reflect disturbed responsiveness of the auditory system toward external stimuli in schizophrenia. With this premise, we investigated the therapeutic utility of neurofeedback training to modulate the auditory-evoked N100 component in patients with schizophrenia and associated auditory verbal hallucinations. Ten patients completed electroencephalography neurofeedback training for modulation of N100 (treatment condition) or another unrelated component, P200 (control condition). On a behavioral level, only the control group showed a tendency for symptom improvement in the Positive and Negative Syndrome Scale total score in a pre-/postcomparison ( t(4) = 2.71, P = .054); however, no significant differences were found in specific hallucination related symptoms ( t(7) = −0.53, P = .62). There was no significant overall effect of neurofeedback training on ERP components in our paradigm; however, we were able to identify different learning patterns, and found a correlation between learning and improvement in auditory verbal hallucination symptoms across training sessions ( r = 0.664, n = 9, P = .05). This effect results, with cautious interpretation due to the small sample size, primarily from the treatment group ( r = 0.97, n = 4, P = .03). In particular, a within-session learning parameter showed utility for predicting symptom improvement with neurofeedback training. In conclusion, patients with schizophrenia and associated auditory verbal hallucinations who exhibit a learning pattern more characterized by within-session aptitude may benefit from electroencephalography neurofeedback. Furthermore, independent of the training group, a significant spatial pre-post difference was found in the event-related component P200 ( P = .04).
A novel wireless visual sensor network protocol based on LoRa modulation
Authors: Fan Chunlei , Ding Qun
Published: March 2018

At present, aiming at complexity of topology and limited network coverage for wireless visual sensor networks so that partial application cannot be implemented. Considering this situation, a novel low-power wide area network protocol is proposed with the purpose of overcoming this disadvantage, which combines LoRa modulation technique with embedded microprocessor technology. This protocol has the advantages of low power consumption, wide coverage, good extensibility, and simple topological structure. This protocol applies to the related fields such as intrusion detection for video intelligent monitoring, which has certain reference significance to research in the wireless visual sensor network field.
“It all started with Eddie”: Thanatopolitics, police power, and the murder of Edward Byrne
Authors: Turner Justin
Published: March 2018

On February 26, 1988, rookie New York City police officer Edward Byrne was shot dead while guarding a material witness in a drug trafficking case in South Jamaica, Queens. This article considers how state narratives and visual rhetoric emerging from Byrne’s murder emboldened the police power and a revanchist campaign aimed at “taking back the streets” secreted under the war on drugs. As such, this case powerfully illustrates a disparate politics of death and the ways that the state enlists thanatopolitical power in order to reaffirm and reproduce its sovereign authority. Such a reproduction or reanimation of power registers as the state’s ability to unleash violence unequivocally and unequally upon poor and marginalized communities, as later demonstrated by the legal and proper police murder of Sean Bell, a resident of South Jamaica, Queens killed by NYPD agents in 2006.
Computational model of enterprise cooperative technology innovation risk based on nerve network
Authors: Yang Changhui , Yang Ruixia , Xu Tingting , Li Yinxia
Published: March 2018

Collaborative innovation has become the principal innovation method because of the puniness of the innovation strength of the enterprises. Due to the objective reality nature of the risk of enterprise collaborative technology innovation, it is necessary to take measures to prevent and indemnify the loss which the risk may bring. Because there is the complex nonlinear function mechanism between risk factors, the cooperative mode and control mechanism of enterprise collaborative innovation can be studied by nonlinear method. First, this paper analyzed the seeking method of enterprise collaborative innovation risk, and then the concept of controlling risk regulation gradient of the cooperating technological innovation under network environment was explained. And a complete controlling risk model of the cooperating technological innovation has been put forward, which is based on the wavelet and nerve network. Finally, the discussion about the conclusion of the research was given.
Surgical site infection after trans urethral resection of the prostate (TURP): 2008–2013 French national SSI surveillance ISO-RAISIN
Authors: Bruyère Franck , Perennec-Olivie Marion , Tanguy Juliette , Aupee Martine , Astagneau Pascal , Jarno Pascal , Malavaud Sandra
Published: March 2018

Objective:

To describe surgical site infection (SSI) after transurethral resection of prostate (TURP) from the French national database.

Methods:

A national SSI surveillance system was implemented in 1999. Each year, the network included urology departments that included at least two months plus one month follow-up, or at least 100 consecutive targeted surgical procedures. A dataset of patients who underwent urology procedures during the six-year period 2008–2013 was made available. SSI diagnosis was made according to standardised CDC criteria. Descriptive analyses were performed using SAS software version 9.4.

Results:

A total of 12,897 TURPs were performed by 89 urology departments. The crude incidence SSI rate was 2.43 (95% confidence interval = 2.16–2.79). The mean delay for diagnosis was 11.9 ± 8.9 days. The treatment of the SSI required a new surgical intervention in 1.35%. In the multilevel multivariate analysis, ASA score and duration of follow-up were the only parameters correlated with the SSI rate.

Conclusions:

On more than 12,000 TURPs surveyed, the SSI rate was 2.43. ASA score and duration of follow-up were the only parameters correlated with the SSI rate.
Adaptive and Personalized Plasma Insulin Concentration Estimation for Artificial Pancreas Systems
Authors: Hajizadeh Iman , Rashid Mudassir , Samadi Sediqeh , Feng Jianyuan , Sevil Mert , Hobbs Nicole , Lazaro Caterina , Maloney Zacharie , Brandt Rachel , Yu Xia , Turksoy Kamuran , Littlejohn Elizabeth , Cengiz Eda , Cinar Ali
Published: March 2018

Background:

The artificial pancreas (AP) system, a technology that automatically administers exogenous insulin in people with type 1 diabetes mellitus (T1DM) to regulate their blood glucose concentrations, necessitates the estimation of the amount of active insulin already present in the body to avoid overdosing.

Method:

An adaptive and personalized plasma insulin concentration (PIC) estimator is designed in this work to accurately quantify the insulin present in the bloodstream. The proposed PIC estimation approach incorporates Hovorka’s glucose-insulin model with the unscented Kalman filtering algorithm. Methods for the personalized initialization of the time-varying model parameters to individual patients for improved estimator convergence are developed. Data from 20 three-days-long closed-loop clinical experiments conducted involving subjects with T1DM are used to evaluate the proposed PIC estimation approach.

Results:

The proposed methods are applied to the clinical data containing significant disturbances, such as unannounced meals and exercise, and the results demonstrate the accurate real-time estimation of the PIC with the root mean square error of 7.15 and 9.25 mU/L for the optimization-based fitted parameters and partial least squares regression-based testing parameters, respectively.

Conclusions:

The accurate real-time estimation of PIC will benefit the AP systems by preventing overdelivery of insulin when significant insulin is present in the bloodstream.
Trends in Tracheostomy After Stroke: Analysis of the 1994 to 2013 National Inpatient Sample
Authors: Chatterjee Abhinaba , Chen Monica , Gialdini Gino , Reznik Michael E. , Murthy Santosh , Kamel Hooman , Merkler Alexander E.
Published: March 2018

Background:

Real-world data on long-term trends in the use of tracheostomy after stroke are limited.

Methods:

Patients who underwent tracheostomy for acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), or subarachnoid hemorrhage (SAH) were identified from the 1994 through 2013 releases of the National Inpatient Sample using previously validated International Classification of Diseases, Ninth Revision, Clinical Modification codes. Survey weights were used to report nationally representative estimates. Our primary outcome was the trend in tracheostomy use during the index stroke hospitalization over the last 20 years. Additionally, we evaluated trends in in-hospital mortality, timing of placement, and discharge disposition among patients who received a tracheostomy.

Results:

We identified 9.9 million patients with AIS, ICH, or SAH in the United States from 1994 to 2013, of which 170 255 (1.7%; 95% confidence interval [CI]: 1.6%-1.8%) underwent tracheostomy. Among all patients with stroke, tracheostomy use increased from 1.2% (95% CI: 1.1%-1.4%) in 1994 to 1.9% (95% CI: 1.8%-2.1%) in 2013, with similar trends across stroke types. From 1994 to 2013, the timing of tracheostomy decreased from 16.5 days (95% CI: 14.9-18.1 days) to 10.3 days (95% CI: 9.9-10.8 days) after mechanical ventilation. In-hospital mortality decreased from 32.6% (95% CI: 29.1%-36.1%) to 13.8% (95% CI: 12.3%-15.3%) among tracheostomy patients; however, discharge to a nonacute care facility increased from 42.9% (95% CI: 38.0%-47.8%) to 83.3% (95% CI: 81.6%-85.0%) and home discharge declined from 9.3% (95% CI: 7.3%-11.3%) to 2.9% (95% CI: 2.1%-3.7%).

Conclusion:

Over the past 2 decades, tracheostomy use has increased among patients with stroke. This increase was associated with earlier placement, reduced in-hospital mortality, and lower rates of home discharge.
To “See” Is to Feel Grateful? A Quasi-Signal Detection Analysis of Romantic Partners’ Sacrifices
Authors: Visserman Mariko L. , Impett Emily A. , Righetti Francesca , Muise Amy , Keltner Dacher , Van Lange Paul A. M.
Published: March 2018

Although gratitude plays a central role in the quality of relationships, little is known about how gratitude emerges, such as in response to partners’ sacrifices. Do people need to accurately see these acts to feel grateful? In two daily experience studies of romantic couples (total N = 426), we used a quasi-signal detection paradigm to examine the prevalence and consequences of (in)accurately “seeing” and missing partners’ sacrifices. Findings consistently showed that sacrifices are equally likely to be missed as they are to be accurately detected, and about half of the time people “see” a sacrifice when the partner declares none. Importantly, “seeing” partners’ sacrifices—accurately or inaccurately—is crucial for boosting gratitude. In contrast, missed sacrifices fail to elicit gratitude, and the lack of appreciation negatively colors the partner’s satisfaction with the relationship when having sacrificed. Thus, these findings illustrate the power that perception holds in romantic couples’ daily lives.
Conversion from insulin glargine U-100 to insulin glargine U-300 or insulin degludec and the impact on dosage requirements
Authors: Pearson Scott M. , Trujillo Jennifer M.
Published: March 2018

Background:

We wanted to determine whether basal insulin requirements change when patients transition from insulin glargine U-100 (Gla-100) to insulin glargine U-300 (Gla-300) or insulin degludec.

Methods:

This study involved subjects seen in the University of Colorado Health Endocrine Clinic who were transitioned from Gla-100 to either Gla-300 ( n = 95) or insulin degludec ( n = 39). The primary outcome was the difference between baseline Gla-100 dose and dose of Gla-300 or insulin degludec prescribed after first follow-up visit within 1–12 months. Secondary outcomes included changes in glycemic control and empiric dose conversion from Gla-100 to Gla-300 or insulin degludec on the day of transition. Wilcoxon rank sum tests evaluated changes in insulin doses, and paired t tests assessed changes in glycemic control using GraphPad statistical software.

Results:

Median daily basal insulin dose increased for individuals transitioned from Gla-100 to Gla-300 from 30 [19–60 interquartile range (IQR)] units at baseline to 34.5 (19–70 IQR) units after follow up ( p = 0.01). For patients transitioned to insulin degludec, dose changes from baseline to follow up were not significantly different ( p = 0.56). At the time of transition, the prescribed dose of Gla-300 or insulin degludec did not significantly differ from the previous dose of Gla-100 ( p = 0.73 and 0.28, respectively), indicating that empiric dose adjustments were not routinely prescribed.

Conclusions:

Patients who transitioned from Gla-100 to Gla-300 had increased basal insulin requirements between visits, while basal insulin requirements for those transitioned from Gla-100 to insulin degludec were not significantly different.
Non‐invasive tests for the detection of oesophageal varices in compensated cirrhosis: systematic review and meta‐analysis
Authors: Sami Sarmed S. , Harman David , Ragunath Krish , Böhning Dankmar , Parkes Julie , Guha Indra Neil
Published: March 2018

Introduction

Conclusive data on the accuracy and clinical applicability of non‐invasive screening tests for oesophageal varices (OV) in patients with compensated cirrhosis remain lacking. We conducted this study to identify currently available tests, estimate their diagnostic performance and then exemplify how these could be utilized in clinical practice.

Materials and methods

A systematic literature search was performed to identify all primary studies that reported accuracy using oesophagogastroduodenoscopy (OGD) as the gold standard. Sources searched included Ovid MEDLINE, Ovid EMBASE and The Cochrane Library databases.

Results

Twenty‐one studies with a total of 2471 patients were identified. Several tests were evaluated in more than three studies. Platelet count/spleen diameter ratio (PSR) had the highest summary area under the curve for detection of any size OV of 0.85 (95% confidence interval 0.78–0.92). At a cut‐off of 909 (n = 4 studies) and prevalence rates of 10, 20, 30, 40 and 50% for OV, PSR screening correctly avoided the need for OGD in 70, 62, 55, 47 and 39% of patients, respectively.

Conclusions

PSR appears to be the most accurate and validated non‐invasive screening test for OV in patients with compensated cirrhosis. At a cut‐off of 909, PSR could be clinically useful to avoid OGDs in a significant proportion of patients.
Risk factors for peri-traumatic distress and appearance concerns in burn-injured inpatients identified by a screening tool
Authors: Oaie Ecaterina , Piepenstock Emma , Williams Lisa
Published: March 2018

Introduction:

Psychosocial screening of burn-injured patients is a National Burn Care Guideline and is increasingly used to identify individuals most in need of support. It can also generate data that can inform our understanding of patient reported concerns following a burn injury.

Method:

As part of routine care, 461 patients admitted to a burns unit were screened soon after admission using a psychosocial screen designed by the service. The questionnaire included items on pre-existing social support, coping, emotional and psychological difficulties, as well as current trauma symptoms and current level of concern about changed appearance following the burn.

Results:

Overall, patients reported low levels of appearance concerns (mean 3.7/10) and trauma symptoms (18% reporting flashbacks) in the initial days following a burn injury. In those who did report concerns, there were some significant associations with demographic and other variables. Patients who experienced flashbacks were younger and had a larger total body surface area (TBSA) burn. Higher levels of appearance concern were associated with younger women, larger TBSA and facial burns. However, the relationships found were weak and frequently confounded by other factors.

Conclusion:

Overall, the findings indicate that initial trauma symptoms and appearance concerns are not inevitable in this group and there is no substitute for screening in identifying who is most at risk.
District Implementation of Research-Based Practices for Transition Planning With Culturally and Linguistically Diverse Youth With Disabilities and Their Families
Authors: Gothberg June E. , Greene Gary , Kohler Paula D.
Published: March 2018

Post-school outcomes are poor for youth with disabilities, in general, but even more discouraging for certain subpopulations of individuals with disabilities, particularly those from culturally and linguistically diverse (CLD) backgrounds. The authors discuss structural inequalities in public schools which potentially contribute to the poorer transition outcomes of CLD youth with disabilities compared with their White peers with disabilities and identify 11 research-based practices (RBPs) for supporting CLD youth with disabilities and their families during the transition planning process. A study is subsequently described involving the development and implementation of a survey measuring the degree to which these 11 RBPs are being implemented in public school districts. The survey was administered during 2011 to 2016 to interdisciplinary transition teams representing more than 90 school districts in the United States who were attending state capacity-building transition services training institutes. Group consensus was sought on the 11 items appearing on the survey. Results from the study found that most school districts were not implementing any of the RBPs to any significant degree, school staff were in need of cultural competence professional development training, CLD families of transition-aged youth with disabilities lacked access to quality resources and supports, and CLD youth with disabilities lacked opportunities to strengthen their self-determination skills. Implications for practice and future research on this topic is presented and discussed.
General Factors of Psychopathology, Personality, and Personality Disorder: Across Domain Comparisons
Authors: Oltmanns Joshua R. , Smith Gregory T. , Oltmanns Thomas F. , Widiger Thomas A.
Published: March 2018

Three separate and distinct literatures exist investigating general factors of psychopathology (p factor), personality (general factor of personality, GFP), and personality disorder (g-PD). Surprisingly, there has been little to no investigation regarding the convergence of these three distinct general factors. In the present investigation, two studies were conducted examining the convergence of the p factor, GFP, and g-PD. In Study 1, a combined model extracting all three factors from self-report data simultaneously found high convergence. The findings for the g-PD and GFP were replicated in Study 2 using multimethod data, wherein the GFP and the g-PD were extracted from a community sample of 1,630 older adults and correlated with an index of maladaptivity. The present findings support the position that general factors of psychopathology, personality disorder, and personality are likely to entail a common individual differences continuum, which may impact on how these general factors are to be understood.
Spontaneous cutaneous endometriosis of the mons pubis: Diagnosis, treatment, and review of the literature
Authors: Lo Lydia , Lee Rebecca
Published: March 2018

Background:

Cutaneous endometriosis is usually associated with a preceding surgical scar; spontaneous cutaneous endometriosis is rare. We report on a case of spontaneous cutaneous endometriosis of the mons pubis as well as a review of the literature.

Case:

A 46-year-old woman with no surgical history presented to gynecology clinic with a 6-year history of a mass on the mons pubis causing severe cyclic pain with enlargement during menses. Initial fine needle aspiration biopsy was nondiagnostic; thus, pelvic ultrasound, magnetic resonance imaging, and a core needle biopsy were used to diagnose a mons endometrioma. The lesion was surgically excised with pathology confirming the diagnosis. The patient noted subsequent improvement in her symptoms.

Conclusion:

Spontaneous cutaneous endometriosis of the mons pubis can be successfully treated via surgical excision.
Early outcomes of arthroplasty of the first carpometacarpal joint using pyrocarbon spherical implants
Authors: Bengezi Omar , Vo Anthony
Published: March 2018

The first carpometacarpal joint (CMC) is the most common hand joint to develop osteoarthritis. A survey found that many hand surgeons have revisited implant arthroplasty because it preserves critical structures. However, there is currently no implant with an ideal design and material composition. The present study was the first to use and evaluate early outcomes of pyrocarbon spherical implants for arthroplasty of the first CMC in patients with Eaton-Littler stage II and III osteoarthritis. A single surgeon performed 24 arthroplasties (23 patients [20 women, three men] with a mean age of 56 years [range 46 to 75 years]) of the first CMC (nine right hands and 15 left hands) using pyrocarbon spherical implants from May 2010 to April 2013. All patients failed conservative management. At a mean (± SD) of 18.5±11.16 months postoperatively (range 4.3 to 38.9 months), the mean Kapandji score was 8.8 of 10 (range 7 to 10), the average pre- and postoperative values on the visual pain scale were 8.96±0.64 of 10 (range 8 to 10) and 1.13±1.22 of 10 (range 0 to 4), respectively. All patients were either very satisfied (score = 5) or satisfied (score = 4) with the procedure, with a mean satisfaction score of 4.76±0.44 of 5.00 (range 4 to 5). The mean postoperative Disabilities of the Arm, Shoulder and Hand (DASH) score was 11.79±14.29 (range 0 to 49.17). The most recent radiographic evaluations confirmed that all implants were stable with no erosion of nearby cancellous bone. There were no implant subluxations, dislocations or revisions. Early outcomes show promising results and support continued use of this implant for arthroplasty. However, longer-term follow-up will be needed to confirm these results.
Meta-analysis of antibiotic prophylaxis in breast reduction surgery
Authors: Shortt Rodger , Cooper Michael J , Farrokhyar Forough , Bain James
Published: March 2018

Background

Breast reduction surgery is a very common procedure; however, there is still no consensus as to whether antibiotics should be used perioperatively.

Objective

To review the world literature and perform a meta-analysis of studies comparing wound infection rates with antibiotic use in breast reduction surgery.

Methods

A literature search was performed using the MEDLINE, Cochrane Database of Systematic Reviews, Cochrane Database of Clinical Trials, Embase and CINAHL databases. Subject headings and relevant subheadings for “Breast”, “Breast Reduction”, “Reduction Mammaplasty”, “Mammaplasty” were combined with “Antibiotics” and “Antibacterial Agents”. The list of titles was assessed by the study's authors and abstracts were reviewed. All relevant articles were then independently reviewed by the two primary authors, and Jadad scoring was used to assess the quality of the included articles.

Results

From the original search, three randomized controlled trials were included in the meta-analysis of preoperative antibiotics. The meta-analysis revealed a 75% reduction in wound infections with preoperative antibiotics (OR 0.25 [95% CI 0.09 to 0.72]). Because only one randomized controlled trial analyzed postoperative antibiotics, no meta-analysis could be performed.

Conclusions

Preoperative antibiotics should routinely be used before breast reduction surgery. The use of postoperative antibiotics remains controversial. Additional randomized studies investigating postoperative antibiotics are needed.