bluuebunny/crossref_metadata_2025 huggingface dataset:
Power Quality in Wind Power Systems
Authors: Z. Leonowicz
Published: July 2017

Wind power generation systems influence power quality in a specific way making important the need for detailed and   accurate   evaluation   of   disturbances   caused   by   wind generators.    Wind    power    system    can    cause    sub-    and interharmonic components to appear in the spectrum of voltages and currents. The  paper  shows  different  aspects  of  spectrum  estimation  in power  systems,  including  the  doubly  fed  induction  generator (DFIG)  connected  to  low  voltage  distribution  grid.  Harmonic distortions  caused  by  wind  generator  under  various  operational conditions regarding wind speed, active and reactive power are shown   and   discussed.   Advanced   spectral    methods   (like ESPRIT)  are  applied  to  overcome  the  drawbacks  of  Fourier-based techniques.
High Efficiency Squirrel Cage Induction Machines
Authors: T. Tudorache  , L. Melcescu  , V. Petre
Published: July 2017

This paper highlights the benefits of replacing the classical cast aluminum cage with a cast copper cage in the manufacture of future generation of high efficiency induction machines used as motors or generators. The numerical analysis carried out in the paper is based on a 2D plane-parallel finite element approach of the induction machine, the numerical results being discussed and compared with experimental measurements.
“Nuevos datos para la descripción dialectal en la confluencia vasco-románica”
Authors: Romero Andonegi Asier
Published: July 2017

Fecha de recepción: 4 de abril de 2011.Fecha de aceptación: 17 de marzo de 2013.Los nuevos estudios que aportan la Lingüística histórica y ciencias aledañas como la Arqueología han revitalizado considerablemente el estudio de las relaciones entre el vasco y el románico, cuyo conocimiento puede contribuir a la reconstrucción sistemática de la consolidación del romance en el área vasca y a una mejor interpretación de ese continuum dialectal septentrional, así como al entendimiento más adecuado del papel desempeñado por el euskara en el español en general.
Anthony Close, Cervantes y la mentalidad cómica de su tiempo. Centro de Estudios Cervantinos, Alcalá de Henares, 2007; 433 pp.
Authors: Gopar Osorio Emiliano
Published: July 2017

Se reseña el libro:Cervantes y la mentalidad cómica de su tiempo.
Mercedes Blanco, Góngora heroico. Las "Soledades" y la tradición épica.Centro de Estudios Europa Hispánica, Madrid, 2012; 443 pp.
Authors: Tenorio Trillo Martha Lilia
Published: July 2017

Se reseña el libro Góngora heroico. Las "Soledades" y la tradición épica.
Wilfrido H. Corral, Cartografía occidental de la novela hispanoamericana. Centro Cultural Benjamín Carrión, Quito, 2010; 387 pp.
Authors: De Castro Juan E.
Published: July 2017

Se reseña el libro:Cartografía occidental de la novela hispanoamericana.
Bibliografía
Authors: Filología Hispánica Nueva Revista de
Published: July 2017

Las reseñas se consignan a continuación del libro (o artículo reseñado. Cuando éste se ha descrito en una entrega anterior de la Bibliografía, se pone entre paréntesis el número de ficha correspondiente. También se hacen referencias a ediciones anteriores de una obra, a tomos anteriores de una obra en curso de publicación, etc. En estos casos, la cifra que precede al número de referencia indica el volumen de laNRFHen que figura la ficha en cuestión. Así, el "núm. 39-39695" corresponde a la ficha 39695, la cual está en el volumen 39 de laNRFH.Cuando no hay cifra inicial, ha de entenderse que el número remite a una ficha incluida en el presente fascículo.
THERAPEUTIC ACTIVITY OF POLYHERBAL FORMULATION AGAINST PASSIVE ANAPHYLAXIS BY USING RAT MESENTERIC MAST CELLS
Authors: Girish C. , Reddy Y. Narsimha
Published: July 2017

Anaphylaxis is the result of alteration in mast cell physiology and is responsible for the various physiological changes which are observed during anaphylaxis. The symptoms of anaphylaxis are due to the release of the histamine from the mast cells and it results mainly due to the degranulation of the mast cells. Antianaphylactic activity of polyherbal formulation against passive anaphylaxis was evaluated with the help of sheep serum induced passive anaphylaxis model and passive paw anaphylaxis model. Sheep serum induced passive anaphylaxis model was carried out by wistar rats. The selected rats were administered intraperitoneally with serum of active anaphylactic rats. After 48 h all the rats are administered intraperitoneally with 1ml of sheep serum. The rats which are pre-treated with prednisolone (10 mg), polyherbal formulation (250 mg) were analyzed for the mast cell degranulation. Passive paw anaphylaxis model was carried out by subcutaneous administration of 0.1 ml serum of active anaphylactic rats into the plantar region of left hind paw of rats. After 24 h the left hind paw of rats was administered subcutaneously with 0.1 ml of egg albumin. The rats which are pre-treated with prednisolone (10 mg), polyherbal formulation (250 mg) were analyzed for the increase in paw volume. Antianaphylactic activity of polyherbal formulation on the mesenteric mast cells of the rat may be possibly due to the membrane stabilizing potential.
The Development Of Collision Module Based On Process Image For Physics Learning In Senior High School
Authors: Mi’rojiyah Fajar Lailatul , Sutarto S , Mahardika I Ketut , Indrawati I , (Page 64-71) Jekti Prihatin
Published: July 2017

This action research explored the development of instructional material in module form based on process image which valid, practice, and effective at physics learning in senior high school. Physics contained the concepts with the fundamental categorizing something into presenting non verbal so the physics concepts are usually abstract so that mental image needed. The development of this module is one of instructional material which can help the student thinking systematic about the physics concepts so that it can learn by students independently. Module must be describing the basic competencies and it will be achieve by students and served with a good language, interesting, and completed by illustration clearly. Process Image interpreted by a series of images (objects, events, phenomenon), which every images of that series always look a different combination overall describing phase stages comprehensive.The development of module in this research is using Thiagarajan design research and development 4D (Define, Design, Develop and Disseminate) and it still at the phase Develop which the result through expert validation and action research that is plan, action, observe, and reflection during the research. Finally the collision module based on process image can be used in physics learning.
Daniels’ Orchestral Music (Book Review)
Authors: Boyd Alastair
Published: July 2017

[no abstract]
Glass Houses for Marimba (CD Review)
Authors: Maloney Timothy
Published: July 2017

[no abstract]
Leonard Cohen and Philosophy: Various Positions (Book Review)
Authors: Montgomery David
Published: July 2017

[no abstract]
Building a Collection of Iranian Music at the University of Toronto Music Library
Authors: Behzadi Houman
Published: July 2017

This paper describes the process of building a collection of Iranian music at the University of Toronto Music Library. The initiative was a response to the noticeable interest in Iranian studies, and more specifically Iranian music, at the University of Toronto. Following an environmental scan, the author elaborates on the observations that identified the need for this project. The rationale for building the collection was further formed through a field trip to Iran, which provided an overview of the country’s print publication and audiovisual production output. A number of opportunities and challenges encountered in acquiring music materials from this country are discussed and the methods used in the selection and acquisition processes explained. Subsequent to an account of the project’s outcomes, the author outlines the current limitations of the collection and discusses areas for its further development and discoverability.
O currículo de matemática nos anos iniciais e o grupo de Educação Matemática do Projeto EMAI de São Paulo
Authors: De Souza Silva Emerson , Prenstteter Gama Renata
Published: July 2017

Esse trabalho busca compreender a construção do currículo nos anos iniciais do Ensino Fundamental, a partir da compreensão dos docentes frente a um novo currículo prescrito e suas transformações nas práticas pedagógicas. Para a construção dos dados, o estudo recorreu a documentos sobre o processo histórico de ensino da Matemática e às mudanças curriculares que ocorreram no decorrer dos anos e foi selecionada uma escola que aderiu ao Projeto EMAI para aplicação de um questionário a todos os docentes. A análise do material do EMAI focou as expectativas de aprendizagem, as hipóteses de aprendizagem das crianças, os encaminhamentos aos docentes para o desenvolvimento do trabalho em sala de aula e o questionário, balizados pelos pressupostos teóricos sobre currículo de Gimeno Sacristán (1998; 2000), que retratou os níveis de currículo. Os resultados apontam aspectos positivos do Projeto EMAI destacando as sequências didáticas como bem elaboradas, contendo atividades diversificadas e o direcionamento do trabalho docente a partir da concepção construtivista e sócio interacionista. Por outro lado, apontam limitações na prática pedagógica em relação à necessidade de sistematização dos conceitos, ao tempo insuficiente para o desenvolvimento das atividades e necessidade de um acréscimo de mais situações-problema nas sequências didáticas. O grupo de Educação Matemática na escola prioriza o currículo prescrito e apresentado para maior entendimento das docentes em uma perspectiva de trabalho colaborativo.
Pharmacognostical, Physicochemical and Preliminary Phytochemical Standardization of Aerial Parts of Onosma bracteatum Wall
Authors: V. G. Patel , K. G. Patel , K. V. Patel , T. R. Gandhi
Published: July 2017

Objective: The present study was undertaken to develop the standardization parameters of powdered aerial parts of Onosma
bracteatum Wall, family Boraginaceae.
Methods: Different parameters such as pharmacognostical, physicochemical, preliminary phytochemical evaluation along
with thin layer chromatography for identification of phytoconstituents were studied.
Results: On microscopical examination of the aerial parts it showed the presence of oval to polygonal thin walled straight
epidermal cells; spiral vessels, a few fibres elongated with blunt tips, long warty, tubercle based unicellular hairs and
paracytic stomata. On physicochemical evaluation it was found to contain more amount of polar constituents as the ethanol
extractive value was found to be more. Total ash value and acid insoluble ash indicated the presence of inorganic acids and
silicaceous matter respectively. Foaming index and swelling index were indicative of saponins and mucilaginous matter
present in the aerial parts. On preliminary phytochemical screening and thin layer chromatographic studies it revealed the
presence of saponins, flavonoids, phenolic compounds and mucilage.
Conclusion: The present work carried out can serve as a purpose for identification, authentication and standardization of
the crude drug.
Determination of Total Phenolic, Tannin, Flavonoid Contents and Evaluation of Antioxidant Property of Amaranthus tricolor (L)
Authors: Pulipati Sowjanya , Babu P. Srinivasa , Naveena U. , Parveen S.K. Rafeeka , Nausheen S.K. Sumaya , Sai M Tanmai Naga
Published: July 2017

Free radicals or reactive oxygen species are involved in various pharmacological conditions. As synthetic antioxidants
possess numerous adverse health effects, the medicinal plants possessing antioxidant components can be used to prevent
harmful effects of reactive oxygen species. In the present study leaves of Amaranthus tricolor Linn were used to prepare
chloroform (CEAT), methanolic (MEAT) and aqueous (AEAT) extracts, analyze the presence of phytochemicals and
evaluation of in-vitro antioxidant property. Quantitative determination of phenols, tannins and flavonoids in leaves
A.tricolor was carried out using spectrophotometric methods. The antioxidant activity was performed by DPPH, p-NDA
radical scavenging methods for different extracts of the plant. The plant species showed that methanolic extract (MEAT)
on higher concentration possess better antioxidant potential when compared with reference standard ascorbic acid. The
plant extracts exhibited strong antioxidant DPPH radical scavenging activity with the IC50 values 290, 657, 830 and 130μg/ml
of MEAT, CEAT, AEAT and ASA respectively. In scavenging hydroxyl radical by p-NDA method the MEAT showed
maximum activity, CEAT showed moderate and AEAT showed minimum activity. The strongest antioxidant activity of
MEAT could be due to the presence of flavonoids and phenols.
Studies on Analysis of Antioxidant and Enzyme Inhibitory Activity of Vitex negundo Linn.
Authors: Prakash Ved , Rana Shelly , Sagar Anand
Published: July 2017

The current study was designed to investigate the leaf extracts of Vitex negundo Linn. for their antioxidant and enzyme
inhibitory (α-amylae and urease) activity. The antioxidant capacity of the different extracts (methanol, acetone and
aqueous) of this plant was evaluated by DPPH (1,1-diphenyl-2-picrylhydrazyl) and reducing power tests. The plant
exhibited good DPPH radical scavenging activity and moderate reducing power potential Further, all the extracts of V.
negundo were reported to possess good anti-alpha amylase and anti-urease activity of greater than 50% in all the solvents
used at a concentration of 1 mg/mL. Thus the study provided scientific evidence to the traditional uses of this plant in the
treatment of obesity, diabetes, ulcers, kidney stones etc. Therefore, the leaf extracts of this plant can be selected for further
investigation to determine their therapeutic potential.
Antidiabetic Activity of Essential Oil of Hedychium spicatum
Authors: Kaur Harleen , Richa Richa
Published: July 2017

A Himalayan plant Hedychium spicatum is medicinally very important as its rhizomes are quite aromatic in nature. In our
study the antidiabetic activity of the oil was studied after extracting the oil from rhizomes using Clevenger apparatus.
The antidiabetic activity was studied in vivo in diabetic male Wistar rats. The reference drug used was glibenclemide.
After administring the rats with plant oil at 0.3ml per rat for 14 days, the blood sample was taken on the last day to check
blood glucose level and various renal function parameters. The histopathological study of pancreas was done for each
group. Gas chromatography-Mass spectrometry (GC-MS) results revealed that the main component in the oil was 1,8
cineole. The results on animal model showed that the oral dose of Hedychium spicatum Essential Oil (HEO) reduced the
blood glucose and urea level of the rats of group 3 and were statistically significant when compared with normal control.
The islets of langerhans of rat pancreas provided with HEO regained normal shape when compared with diabetic control
group, emphasizing the antidiabetic potential of the plant essential oil.
A Study of the Physico-Chemical and Phytochemical Parameters of Leaves of Mallotus rhamnifolius
Authors: V. Loganathan , M Devi Kaniakumari , P. Selvakumar
Published: July 2017

India being a rich and varied collection of medicinal plants since the Vedic age. The present study deals with the
phytochemical screening of Mallotus rhamnifolius leaves of extraction belonging to family Euphorbiaceae. This study
includes preparedness of different extracts by successive solvent extraction of varying polarity of Petroleum ether,
chloroform, ethyl acetate, and Ethanol: water (95:5) extracts for detailed analysis. Phytochemical screening determinate
by some chemical tests study was carried out for different solvent extracts. Phytochemical screening reflects existence of
alkaloids, glycosides, saponins, phenolic compounds, tannins, phytosterols, carbohydrates, proteins, amino acids,
flavanoids, quinones and terpenoids which may be responsible for their therapeutic effects. Different physicochemical
parameters such as Loss on drying, Total ash, Acid insoluble ash and Water soluble ash were carried out as per WHO
recommended physicochemical determinations and authentic phytochemical procedures. The results obtained in present
study indicated Mallotus rhamnifolius leaves as a rich source of medicinally compounds and provides evidences that
solvent extracts of Mallotus rhamnifolius contains medicinally important bioactive compounds and this justifies the use
of plant species as medicine for treatment of various diseases.
Inhibition of Alpha-Amylase Activity by Gymnocarpos decandrus Forssk. Constituents
Authors: Sallam Amal , Galala Amal A
Published: July 2017

The methanolic extract of the aerial parts of Gymnocarpos decandrus, the plant growing wildly in the middle east area
and north Africa, showed a promising -amylase inhibitory activity. The ethyl acetate fraction of the plant showed the
highest inhibitory activity followed by the methylene chloride fraction. Phytochemical investigation of both fractions led
to the isolation of 10 compounds; oleanolic acid (1), maslinic acid (2), apigenin (3), β-sitosterol glucoside (4), luteolin
(5), afzelechin (6), epiafzelechin (7), catechin (8), epicatechin (9) and gallocatechin (10). The structures of compounds
1-10 were established on the basis of extensive 1D- and 2D-NMR spectroscopic techniques. This is the first report for the
isolation of these compounds from G. decandrus. The phenolic compounds (6-10) isolated from the ethyl acetate fraction
showed the highest -amylase inhibitory activity. The more the hydroxylation pattern of the isolated phenolic
compounds (6, 8, 9 and 10), the higher the ability to inhibit the -amylase activity. This was confirmed through the
molecular docking experiment. The wild plant G. decandrus is a promising -amylase inhibitor that can be used in the
management of obesity and diabetes mellitus.
Evaluation of Anti-Tumour Potential of Acanthus ilicifolius (Linn.) in HepG2 Cell Line Induced Hepatocellular Carcinoma in Mice
Authors: Vijayaraj R. , Kumaran Sri , Swarnakala Swarnakala
Published: July 2017

Acanthus ilicifolius has long history of medicinal plant belong to the family Acanthaceae. In the present study, ethanolic
extract of A. ilicifolius showed antitumour potential against HepG2 cell line induced hepatocarcinoma in mice. The
phytochemical analysis were studied by using strandard methods. The heptocarcinoma mice were orally treated with
extract of A.ilicifolius (500 mg/kg B.W). The result indicates the presence of phytoconstituents such as Protein (2.5%),
Carbohydrates (0.16%) , alkaloids (0.42%), flavonoids (0.62%), saponins (4.5%), tannins (1.0%) and terpenoids (0.20%).
In FTIR spectrum of test sample, the strong absorbance were showed at peak 678.94 cm-1, 1514.12 cm-1,1741.72 cm-1
,2304.94 cm-1, 3597.24 cm-1, 3728.40 cm-1 which are associated with presence of functional groups such as Mono
substituted benzene, aromatic (c=c), aldehyde (c=o), disubstituted alkynes(c=c), alcohols with free hydroxyl group (OH),
alcohols, phenols (O-H). Treatment effectively suppressed HepG2 cells induced mice as revealed by decrease in the
levels and extend of Alanine transaminase (84.3±1.86), Aspartate transaminase (41.6±2.15), Alkaline phosphatase
(224.9±6.3), Urea (64.3±1.20) and creatinine (1.36±0.155). Histopathological analysis of liver and kidney was also
evaluated. This study demonstrates that the A. ilicofolius have a potent anticancer Properties.
Molecular Modeling and Docking Analysis Of Callosobruchus maculates Cytochrome B Proteins with Bio Active Compound Phytolfrom Glinus lotoides and Synthetic Pesticide Pirimiphos-Methyl
Authors: Daniel Adline Jennefa , C. Gunasekaran
Published: July 2017

Cytochrome b is a component of respiratory chain complex III, also known as bc1 complex or ubiquinol-cytochrome c
reductase. These complexes are involved in electron transport and generation of ATP and thus play a vital role in electron
transport chain. Phytol is a phytochemical derived from ethyl acetate extract of Glinus lotoides. Cytochrome b modeled
and the structure was used for In-silico binding efficiency and comparative analysis of cytochrome b with Phytol and
synthetic pesticide were showed good docking score and binding affinity when compared to control. This study will be
used in broad screening of the protein in the respiratory process and can be further implemented in designing pest control.
Zapewnienie bezpieczeństwa żywności w logistycznych procesach zaopatrzeniowych oraz magazynowania na przykładzie przemysłu cukierniczego
Authors: Janczewska Danuta
Published: July 2017

Przedsiębiorstwa produkcyjne realizują swoje cele, a głównym są procesy zakupów logistycznych. Gwarancją bezpieczeństwa żywności są niezbędne warunki transportu i przechowywania surowców oraz materiałów opakowaniowych. Na przykładzie branży spożywczej można potwierdzić, że głównym celem jest bezpieczeństwo produktów spożywczych. Celem artykułu jest przedstawienie systemu HACCP w zarządzaniu procesami logistycznymi, w szczególności zakupami i magazynowaniem. W artykule przedstawiono studium przypadku systemu zarządzania jakością opartego na HACCP w przedsiębiorstwie cukierniczym.
The Concept of Homo Economicus in Economic Theory: An Outline of the Evolution
Authors: Zalega Tomasz
Published: July 2017

The evolution and progress in economic studies that have occurred in the past five decades provide a theoretical basis for changing the paradigm of homo economicus. Today, economics is constantly expanding and becoming more and more diverse internally, combining its own reflections with other social sciences, chiefly psychology, sociology and philosophy. As part of the interdisciplinary exchange, new methodologies and scientific approaches are emerging that are directed towards a more holistic view of economic processes and the functioning of entities in the market. Thus, the classical axiom of a rational man is being abandoned, with the concept of an emotional man gaining in importance. This approach resulted in the emergence of alternative ways of understanding homo economicus. This article aims to outline the concept of homo economicus. The issues herein do not describe its whole range, but only selected elements. The first part focuses on the origins and elements of the homo economicus concept. Further, the most important criticisms of this notion are discussed, together with the most significant alternative ways of understanding homo economicus.
Influence of phonon confinement on the optically detected electrophonon resonance linewidth in parabolic quantum wells
Authors: Hien Nguyen Dinh
Published: July 2017

We investigate the influence of optical phonon confinement described by Huang-Zhu (HZ) model on the optically detected electrophonon resonance (ODEPR) effect and ODEPR linewidth (ODEPRLW) in parabolic quantum wells (PQW) by using the operator projection. The obtained numerical result for the GaAs/AlAs parabolic quantum well shows that the ODEPR linewidths depend on the well's confinement frequency. Besides, in the two cases of confined and bulk phonons, the linewidth (LW) increases with the increase of confinement frequency. Furthermore, in the large range of the confinement frequency, the influence of phonon confinement plays an important role and cannot be neglected in considering the ODEPR linewidth.
Economic Burden of Unintended Pregnancies from Societal Perspective: A Case of Nepal
Authors: Sapkota Vishnu Prasad , Dhakal Liladhar , Adhikari Shiva Raj
Published: July 2017

Introduction: Unintended pregnancy includes unwanted and mistimed pregnancy. Nepal has high proportion of unintended pregnancies. An unintended pregnancy has cost implication through different medical conditions to individual, service provider and society. However, till date there is no information about how much cost does the unintended pregnancy incur to the society in Nepal. The objective of this study is to estimate the national annual economic burden of unintended pregnancies in Nepal.Methods: This study adopted societal perspective to identify, measure and value the resources required to manage pregnancy outcomes. The costs include direct medical costs, direct non-medical costs and indirect costs. We collected data for this study from 27 hospitals and 121 maternal service clients. Transition probabilities were taken from several secondary sources. Total annual burden of unintended pregnancy was estimated by a Markov model using the cohort simulation approach. The input parameters in the model were costs and likelihood of occurrence of the given pregnancy outcome.Findings: Total annual burden of unintended pregnancies was estimated to be 2649.558 and 12330.59 NPR from provider and societal perspective. The greatest share of the burden was borne by delivery services followed by management of maternal and ANC check-ups. The total burden is most sensitive to cost of normal delivery, CS and ANC services.Conclusion: Majority of unintended pregnancies undergo full term pregnancy incurring huge economic burden to the society. National Annual economic burden was estimated to be around 2649.558 and 12330.59 NPR from provider and societal perspective. Programs reducing unintended pregnancies will provide economic benefit to the society. Economic Journal of Development Issues Vol. 19 & 20 No. 1-2 (2015) Combined Issue, Page: 83-99
Clinical profile and early outcome of arteriovenous fistula creation for Haemodialysis: Integrated activity in a general surgery unit
Authors: Lamichhane Deep , Paudyal Sanjay , Maskey Pukar , Maharjan Santa Bir , Joshi Arbin , Pandey Bimal , Shah Jay Narayan , Jaiswal Vijay Kumar
Published: July 2017

Introduction: A functioning arteriovenous fistula (AVF) is essential for maintenance hemodialysis (HD) in a patient with chronic renal failure. This study explores the creation of AVF as an integral activity in a general surgical unit by a general surgeon.

Methods: This is a hospital based cross sectional study done at Patan Hospital patients who underwent creation of AVF from January 2015 to June 2015 were included in the study. Patient demographic and clinical data were documented. Outcome and complications of AVF surgery were obtained over a 6 months period from the time of vascular access creation.

Results: Thirty-seven patients were operated in the study period with a mean age of 35.44 years and M: F ratio of 2.7:1. There were 3 immediate and 3 delayed failure with 81.81% (n=27) patency rate at 6 months follow up. The maturation time was 3-7weeks (mean +/- SD of 4.83 +/- 1.053). Complication occurred in 4 patients, namely arm edema (n=3) and haematoma (n=1).

Conclusion: The creation of AVF for HD performed in a general surgery unit is a safe procedure with satisfactory outcome and acceptable level of complications.
Finding Balance: An Evaluation Governance Model to Ease Tension between Independence and Inclusion
Authors: McLean Robert K. D. , Finner Kaitlyn , Woodward Lisa , Dumaine François , Graham Kathryn , Mackie Jocelyn E. , Peckham David , Wehr Kathryn
Published: July 2017

Abstract: Practitioners and theorists have documented the benefits of user engagement and participation in evaluation and, at the same time, the value of neutral and impartial evaluative evidence. Yet producing both an independent and inclusive evaluation is a leading challenge in our field. In this practice note, we present one solution. We describe the design of an evaluation governance structure that was used to find balance between these two themes. We also identify key elements of this experience and present these for adaptation by others, given appropriate tailoring. We have documented our experience as we believe that governance provides currently uncharted potential for this discipline spanning challenge.
La fidélité d’implantation d’un programme probant au-delà de son implantation initiale : l’exemple de Ces années incroyables en protection de l’enfance de 2003 à 2013
Authors: Leclair M. Isabelle-Ann , Paquette Geneviève , Letarte Marie-Josée
Published: July 2017

Abstract: This article presents a study describing the fidelity of implementation of an evidence-based program and its evolution over a period of 10 years. From this study, the authors establish links between the implementation of programs, their effects, and their sustainability and discuss some of the issues surrounding the measurement of fidelity of implementation. This discussion addresses elements that may influence the fidelity of implementation and the sustainability of the studied program, including adaptations made to it. The advantages and limitations of using a quantitative approach to the evaluation of implementation to produce a portrait of implementation are also presented.
Strategies for Monitoring Multiuse Trail Networks
Authors: Lindsey Greg , Wilson Jeffrey S. , Wang Jueyu , Hadden-Loh Tracy
Published: July 2017

Many municipalities, park districts, and nonprofit organizations have begun monitoring nonmotorized traffic on multiuse trails as the need for information about the use of facilities has grown and relatively low-cost sensors for automated monitoring have become available. As they have gained experience, they have begun to move from site-specific monitoring on individual trails to a more comprehensive monitoring of trail networks. This case study review compares strategies developed by 10 organizations for monitoring traffic on multiuse trails, including local, multicounty, statewide, and multistate trail networks. The focus is on approaches to the design of monitoring networks, particularly the rationales or objectives for monitoring and the selection of monitoring sites. It is shown that jurisdictions are following principles of monitoring established by FHWA and that the design of monitoring networks is evolving to meet new challenges, including monitoring large-scale networks. Relevant outcomes and implications for practice are summarized. The researchers concluded that FHWA guidelines can be adapted to many circumstances and can increase information for decision making. Trail monitoring is informing decisions related to facility planning, investment, and safety.
À quoi pensent les institutions ?
Authors: Acquier Aurélien , Carbone Valentina , Massé David
Published: July 2017

Cet article développe une approche cognitive et discursive des institutions. Par une analyse des discours d’entrepreneurs, les auteurs identifient quatre traditions théoriques qui sous-tendent l’émergence de l’économie collaborative. Ils révèlent ainsi les tensions qui traversent ce champ, et formulent des propositions pour l’analyse des processus d’institutionnalisation de champs émergents marqués par la coexistence de plusieurs référentiels théoriques et normatifs.
L’émergence de la valeur d’usage et l’« agentivité » des objets matériels
Authors: Marion Gilles
Published: July 2017

Cet article examine le processus d’émergence de la valeur d’usage. Après le rappel de la distinction entre valeur d’échange et valeur d’usage, il montre que cette dernière émerge de la relation interactive entre les possibilités d’action d’un objet et la compétence d’un sujet. Tout objet apparaît comme un médiateur entre le monde naturel et la sensibilité d’un sujet et, de ce point de vue, il est doté d’une agentivité. Il peut « faire faire » des actes à un sujet, cadrer son action et, ce faisant, il peut le configurer. Quelques conséquences de cette perspective sur le travail de conception sont examinées.
La convergence du public vers le privé, de la pertinence à la dépendance
Authors: Rocher Sébastien
Published: July 2017

Les pratiques du secteur privé sont souvent évoquées comme une solution pour la modernisation du management des organisations publiques. Si ce choix peut apparaître pertinent à court terme, la question de ses conséquences à long terme reste encore à définir. Par une analyse de la stratégie de normalisation du normalisateur international de comptabilité publique entre 1996 et 2012, cet article montre que le choix de donner la priorité à l’adaptation au secteur public des normes internationales de comptabilité privée plutôt qu’aux problèmes spécifiques du secteur public, a entraîné le normalisateur dans une dépendance aux résultats contreproductifs.
Failure of ETV in patients with the highest ETV success scores
Authors: Gianaris Thomas J. , Nazar Ryan , Middlebrook Emily , Gonda David D. , Jea Andrew , Fulkerson Daniel H.
Published: July 2017

OBJECTIVE

Endoscopic third ventriculostomy (ETV) is a surgical alternative to placing a CSF shunt in certain patients with hydrocephalus. The ETV Success Score (ETVSS) is a reliable, simple method to estimate the success of the procedure by 6 months of postoperative follow-up. The highest score is 90, estimating a 90% chance of the ETV effectively treating hydrocephalus without requiring a shunt. Treatment with ETV fails in certain patients, despite their being the theoretically best candidates for the procedure. In this study the authors attempted to identify factors that further predicted success in patients with the highest ETVSSs.

METHODS

A retrospective review was performed of all patients treated with ETV at 3 institutions. Demographic, radiological, and clinical data were recorded. All patients by definition were older than 1 year, had obstructive hydrocephalus, and did not have a prior shunt. Failure of ETV was defined as the need for a shunt by 1 year. The ETV was considered a success if the patient did not require another surgery (either shunt placement or a repeat endoscopic procedure) by 1 year. A statistical analysis was performed to identify factors associated with success or failure.

RESULTS

Fifty-nine patients met the entry criteria for the study. Eleven patients (18.6%) required further surgery by 1 year. All of these patients received a shunt. The presenting symptom of lethargy statistically correlated with success (p = 0.0126, odds ratio [OR] = 0.072). The preoperative radiological finding of transependymal flow (p = 0.0375, OR 0.158) correlated with success. A postoperative larger maximum width of the third ventricle correlated with failure (p = 0.0265).

CONCLUSIONS

The preoperative findings of lethargy and transependymal flow statistically correlated with success. This suggests that the best candidates for ETV are those with a relatively acute elevation of intracranial pressure. Cases without these findings may represent the failures in this highly selected group.
Emergency resection of brainstem cavernous malformations
Authors: Tumturk Abdulfettah , Li Yiping , Turan Yahya , Cikla Ulas , Iskandar Bermans J. , Baskaya Mustafa K.
Published: July 2017

Brainstem cavernous malformations (CMs) pose significant challenges to neurosurgeons because of their deep locations and high surgical risks. Most patients with brainstem CMs present with sudden-onset cranial nerve deficits or ataxia, but uncommonly patients can present in extremis from an acute hemorrhage, requiring surgical intervention. However, the timing of surgery for brainstem CMs has been a controversial topic. Although many authors propose delaying surgery into the subacute phase, some patients may not tolerate waiting until surgery. To the best of the authors’ knowledge, emergency surgery after a brainstem CM hemorrhage has not been described. In cases of rapidly progressive neurological deterioration, emergency resection may often be the only option. In this retrospectively reviewed small series of patients, the authors report favorable outcomes after emergency surgery for resection of brainstem CMs.
Delayed treatment of ruptured brain AVMs: is it ok to wait?
Authors: Beecher Jeffrey S. , Lyon Kristopher , Ban Vin Shen , Vance Awais , McDougall Cameron M. , Whitworth Louis A. , White Jonathan A. , Samson Duke , Batjer H. Hunt , Welch Babu G.
Published: July 2017

OBJECTIVE

Despite a hemorrhagic presentation, many patients with arteriovenous malformations (AVMs) do not require emergency resection. The timing of definitive management is not standardized in the cerebrovascular community. This study was designed to evaluate the safety of delaying AVM treatment in clinically stable patients with a new hemorrhagic presentation. The authors examined the rate of rehemorrhage or neurological decline in a cohort of patients with ruptured brain AVMs during a period of time posthemorrhage.

METHODS

Patients presenting to the authors’ institution from January 2000 to December 2015 with ruptured brain AVMs treated at least 4 weeks posthemorrhage were included in this analysis. Exclusion criteria were ruptured AVMs that required emergency surgery involving resection of the AVM, prior treatment of AVM at another institution, or treatment of lesions within 4 weeks for other reasons (subacute surgery). The primary outcome measure was time from initial hemorrhage to treatment failure (defined as rehemorrhage or neurological decline as a direct result of the AVM). Patient-days were calculated from the day of initial rupture until the day AVM treatment was initiated or treatment failed.

RESULTS

Of 102 ruptured AVMs in 102 patients meeting inclusion criteria, 7 (6.9%) failed the treatment paradigm. Six patients (5.8%) had a new hemorrhage within a median of 248 days (interquartile range 33–1364 days). The total “at risk” period was 18,740 patient-days, yielding a rehemorrhage rate of 11.5% per patient-year, or 0.96% per patient-month. Twelve (11.8%) of 102 patients were found to have an associated aneurysm. In this group there was a single (8.3%) new hemorrhage during a total at-risk period of 263 patient-days until the aneurysm was secured, yielding a rehemorrhage risk of 11.4% per patient-month.

CONCLUSIONS

It is the authors’ practice to rehabilitate patients after brain AVM rupture with a plan for elective treatment of the AVM. The present data are useful in that the findings quantify the risk of the authors’ treatment strategy. These findings indicate that delaying intervention for at least 4 weeks after the initial hemorrhage subjects the patient to a low (< 1%) risk of rehemorrhage. The authors modified the treatment paradigm when a high-risk feature, such as an associated intracranial aneurysm, was identified.
Atypical choroid plexus papilloma: spontaneous resolution of diffuse leptomeningeal contrast enhancement after primary tumor removal in 2 pediatric cases
Authors: Scala Marcello , Morana Giovanni , Milanaccio Claudia , Pavanello Marco , Nozza Paolo , Garrè Maria Luisa
Published: July 2017

Atypical choroid plexus papillomas can metastasize in the form of leptomeningeal seeding. Postoperative chemotherapy is the recommended first-line treatment when gross-total removal is not achieved or in cases of disseminated disease. Here the authors report on 2 children with atypical choroid plexus papillomas and MRI findings of diffuse leptomeningeal enhancement at diagnosis, later presenting with spontaneous resolution of the leptomeningeal involvement after removal of the primary lesions. Observations in this report expand our knowledge about the natural history and biological behavior of these tumors and highlight the role of close neuroimaging surveillance in the management of atypical choroid plexus papillomas in cases with MRI evidence of diffuse leptomeningeal enhancement at presentation.
Minimally invasive dual iliac screw, dual rod fixation in a rare case of pathological sacral fracture from a paraganglionoma: a technique description
Authors: Hasan Muhammed Yaser , Liu Gabriel
Published: July 2017

The management of lumbosacral neoplastic disease can be demanding, often requiring complex reconstruction. In the context of extensive sacral involvement, the risk of iliac screw breakage is greater. Few studies advocate the use of dual iliac screw techniques to reduce implant failure. In this report, the authors have described the first case of percutaneous dual iliac screw, dual rod insertion as part of a minimally invasive spinopelvic stabilization in a patient with a sacral fracture from a paraganglionoma. The patient underwent percutaneous L-2 to ilium fixation. A dual iliac screw, dual rod construct was used for stabilizing the left lumbopelvic junction. At the 1-year follow-up, the patient remained asymptomatic, with radiographs showing no signs of instrumentation failure. Minimally invasive dual iliac screw, dual rod fixation is a viable option in cases in which additional stability is required due to extensive neoplastic disease or active individuals have increased functional demands. Short-term results in this report are encouraging; however, more research is warranted to establish the procedure’s long-term safety.
Surgical and molecular considerations in the treatment of pediatric thalamopeduncular tumors
Authors: Lee Ryan P. , Foster Kimberly A. , Lillard Jock C. , Klimo Paul , Ellison David W. , Orr Brent , Boop Frederick A.
Published: July 2017

OBJECTIVE

Thalamopeduncular tumors are a group of pediatric low-grade gliomas that arise at the interface of the thalamus and brainstem peduncle. They typically occur within the first 2 decades of life, presenting with progressive spastic hemiparesis. Treatment strategies, including surgical intervention, have varied significantly. The authors present their experience in the treatment of 13 children, ages 2–15 years, with non-neurofibromatosis–related pilocytic astrocytomas located in the thalamopeduncular region.

METHODS

Between 2003 and 2016, 13 children presenting with progressive spastic hemiparesis due to a pilocytic astrocytoma at the interface of the thalamus and cerebral peduncles were identified. Medical records were reviewed retrospectively for clinical, radiological, pathological, and surgical data. Formalin-fixed, paraffin-embedded tissue was obtained for 12 cases and tested for KIAA1549-BRAF fusion and BRAF V600E point mutation.

RESULTS

On preoperative diffusion tensor imaging tractography (performed in 12 patients), the ipsilateral corticospinal tract was displaced laterally in 1 case (8.3%), medially in 1 case (8.3%), anterolaterally in 10 cases (83%), and posteriorly in no cases. Ten patients underwent resection via a transtemporal, transchoroidal approach, which was chosen to avoid further damage to motor function in cases of tumors that caused anterolateral or medial corticospinal tract displacement. With this approach, complications included hemianopia, oculomotor palsy, and tremor at a rate of 50%. Among the 12 patients with obtainable follow-up (mean 50.9 months), none received adjuvant therapy, and only 2 (17%) experienced recurrence or progression. KIAA1549-BRAF fusions were present in 10 cases (83%), while BRAF V600E was absent (0%). The 2 fusion-negative tumors had clinical features atypical for the series, including multi-focality and infiltration.

CONCLUSIONS

Transcortical, transchoroidal resection of thalamopeduncular tumors through the middle temporal gyrus allows for a high rate of gross-total resection and cure. Diffuse tensor tractography is a critical component of the preoperative planning process to determine the location of white matter tracts in proximity. Molecular status may correlate with clinical features, and the presence of BRAF lesions offers an additional target for future novel therapeutics.
Lysosomal Regulation of mTORC1 by Amino Acids in Mammalian Cells
Authors: Yao Yao , Jones Edith , Inoki Ken
Published: July 2017

The mechanistic target of rapamycin complex 1 (mTORC1) is a master regulator of cell growth in eukaryotic cells. The active mTORC1 promotes cellular anabolic processes including protein, pyrimidine, and lipid biosynthesis, and inhibits catabolic processes such as autophagy. Consistent with its growth-promoting functions, hyper-activation of mTORC1 signaling is one of the important pathomechanisms underlying major human health problems including diabetes, neurodegenerative disorders, and cancer. The mTORC1 receives multiple upstream signals such as an abundance of amino acids and growth factors, thus it regulates a wide range of downstream events relevant to cell growth and proliferation control. The regulation of mTORC1 by amino acids is a fast-evolving field with its detailed mechanisms currently being revealed as the precise picture emerges. In this review, we summarize recent progress with respect to biochemical and biological findings in the regulation of mTORC1 signaling on the lysosomal membrane by amino acids.
Bimetallic Nanoparticles in Alternative Solvents for Catalytic Purposes
Authors: Dang-Bao Trung , Pla Daniel , Favier Isabelle , Gómez Montserrat
Published: July 2017

Bimetallic nanoparticles represent attractive catalytic systems thanks to the synergy between both partners at the atomic level, mainly induced by electronic effects which in turn are associated with the corresponding structures (alloy, core-shell, hetero-dimer). This type of engineered material can trigger changes in the kinetics of catalyzed processes by variations on the electrophilicity/nucleophilicity of the metal centers involved and also promote cooperative effects to foster organic transformations, including multi-component and multi-step processes. Solvents become a crucial factor in the conception of catalytic processes, not only due to their environmental impact, but also because they can preserve the bimetallic structure during the catalytic reaction and therefore increase the catalyst life-time. In this frame, the present review focuses on the recent works described in the literature concerning the synthesis of bimetallic nanoparticles in non-conventional solvents, i.e., other than common volatile compounds, for catalytic applications.
The Association between Non-Alcoholic Fatty Liver Disease and Cardiovascular Risk in Children
Authors: Di Sessa Anna , Umano Giuseppina , Miraglia del Giudice Emanuele
Published: July 2017

The rising prevalence of childhood obesity in the past decades has made Non-Alcoholic Fatty Liver Disease (NAFLD) the most common cause of pediatric chronic liver disease worldwide. Currently, a growing body of evidence links NAFLD with cardiovascular disease (CVD) even at an early age. Data on the pediatric population have shown that NAFLD could represent an independent risk factor not only for cardiovascular events but also for early subclinical abnormalities in myocardial structure and function. Briefly, we review the current knowledge regarding the relationship between pediatric NAFLD and cardiovascular risk in an attempt to clarify our understanding of NAFLD as a possible cardiovascular risk factor in childhood.
Modeling Real Exchange Rate Persistence in Chile
Authors: Salazar Leonardo
Published: July 2017

The long and persistent swings in the real exchange rate have for a long time puzzled economists. Recent models built on imperfect knowledge economics seem to provide a theoretical explanation for this persistence. Empirical results, based on a cointegrated vector autoregressive (CVAR) model, provide evidence of error-increasing behavior in prices and interest rates, which is consistent with the persistence observed in the data. The movements in the real exchange rate are compensated by movements in the interest rate spread, which restores the equilibrium in the product market when the real exchange rate moves away from its long-run benchmark value. Fluctuations in the copper price also explain the deviations of the real exchange rate from its long-run equilibrium value.
The Nonlinearity of the New Keynesian Phillips Curve: The Case of Tunisia
Authors: Kobbi Imen , Gabsi Foued-Badr
Published: July 2017

This article seeks to check the nonlinearity of the Phillips curve in Tunisia for the 1993–2012 period, relying on a hybrid new Keynesian Phillips curve modeled via a Logistic Smooth Transition Regression (LSTR) model with endogenous variables. We estimate this model using the nonlinear instrumental variables. The empirical results corroborate the new Keynesian assumption ofprice rigidity and show that the response of inflation to the output gap tends to be significant only if the inflation rate tends to be relatively high and exceeds a certain threshold. For a low inflation rate, the price rigidity dominates. This result is particularly evident in Tunisia, especially for the years following the 2011 revolution during which the elasticity of inflation rate to an excess demand has become highly important and the inflation rate experienced record levels.