bluuebunny/crossref_metadata_2025 huggingface dataset:
A Cross-Sectional Study on the Flood Emergency Preparedness among Healthcare Providers in Saudi Arabia
Authors: Al-Wathinani Ahmed M. , Alakeel Abdulaziz , Alani Ahmad Hecham , Alharbi Mohammad , Almutairi Abdullah , Alonaizi Tahani , Alhazmi Riyadh A. , Alghadeer Sultan M. , Mobrad Abdulmajeed M. , Goniewicz Krzysztof , Khorram-Manesh Amir , Hertelendy Attila J.
Published: February 2021

This study used a descriptive cross-sectional methodology to measure healthcare workers’ knowledge, attitudes, perceptions, and willingness to respond to a flood scenario in Saudi Arabia. A validated survey was distributed to collect data using a convenience sampling technique through multiple social media platforms. A total of 227 participants were included in this study: 52% of them were aged between 26 to 34 years, 74% were residents from Riyadh, and 52.4% worked in nursing divisions. A significant number of respondents (73.2%) had positive perceptions towards their hospitals’ ability to provide an effective response to a flood, 89% were willing to report to work following a flood, and 90% of participants reported the need to develop both guidelines and training for flood disaster preparedness. Preparation and successful flood mitigation in the hospital setting requires staff that have both knowledge and training in emergency management. One way to obtain such readiness is through competency-based training, including both table-top and full-scale live exercises. Although the willingness to respond to such a flooding emergency was high among staff, the development of guidelines and educational programs is needed in order to develop the competencies and skills sets to improve disaster preparedness response and preparedness efforts.
Considerations in Planning Physical Activity for Older Adults in Hot Climates: A Narrative Review
Authors: See Lydia , Rasiah Rohan L. , Laing Rachael , Thompson Sandra C.
Published: February 2021

Regular physical activity has multiple health benefits for both the prevention and management of disease, including for older adults. However, additional precautions are needed with ageing given physiological changes and the increasing prevalence of comorbidities. Hot ambient temperatures increase the risks of exercise at any age, but are particularly important given thermoregulatory changes in older people. This narrative review informs planning of physical activity programs for older people living in rural areas with very hot climates for a period of the year. A multi-database search of peer-reviewed literature was undertaken with attention to its relevance to Australia, starting with definitions and standard advice in relation to physical activity programming and the incremental limitations imposed by age, rurality, and extreme heat. The enablers of and barriers to increasing physical activities in older adults and how they can be modified for those living in extreme hot climates is described. We describe multiple considerations in program design to improve safety, adherence and sustaining physical activity, including supervision, simple instructions, provision of reminders, social support, encouraging self-efficacy. Group-based activities may be preferred by some and can accommodate special populations, cultural considerations. Risk management is an important consideration and recommendations are provided to assist program planning.
Does Work Disability Contribute to Trajectories of Work Participation before and after Vocational Labour Market Training for Job Seekers?
Authors: Leinonen Taina , Viikari-Juntura Eira , Räisänen Heikki , Sundvall Santtu , Kauhanen Antti , Solovieva Svetlana
Published: February 2021

The contribution of ill-health to labour market participation in relation to vocational training is unclear. Using nationally representative Finnish register data on 42,691 vocational labour market trainees in 2008–2010, we constructed latent trajectory groups of work participation in the open labour market three years before and after training, identifying groups called “High–High”, “High–Low”, “Low–High”, and “Low–Low”. We plotted further patterns of labour market participation within these trajectory groups and, using multinomial logistic regression, examined assignment to these groups focusing on previous work disability status. Those with compared to those without previous work disability had previous employment more often and spent less time in economic inactivity within the two trajectory groups with low pre-training levels of work participation. Having a previous work disability was associated with assignment to the “High–Low” trajectory group of work participation instead of the “High–High” comparison group. The associations of other background factors with the assignment to the different trajectory groups were relatively similar amongst those with and without previous work disability. However, some of these associations were weaker amongst the former. Along with other key background factors, previous work disability should be accounted for when assessing the effects of vocational training.
Validation of the Disaster Preparedness Evaluation Tool for Nurses—The Korean Version
Authors: Han Suk Jung , Chun Jiyoung
Published: February 2021

(1) Background: The purpose of this study was to validate a Korean version of the disaster preparedness evaluation tool (DPET-K) for nurses and to verify its validity and reliability for use in community healthcare centers and hospitals in South Korea; (2) Methods: In total, 497 nurses (248 for exploratory factor analysis and 249 for confirmatory factor analysis) at public health centers, public health sub-centers, public health clinics, and general hospitals in Seoul and Gyeonggi, Chungcheong, and Gangwon Provinces participated in this study. The tool went through translation and back-translation, content validity verification, a pilot survey, and validity and reliability testing; (3) Results: The DPET-K had 28 items with five factors (disaster education and training, disaster knowledge and information, bioterrorism and emergency response, disaster response, and disaster evaluation). The Cronbach’s α values for internal consistency were 0.766–0.953 for the five subscales of the DPET-K. A structural equation model was built through confirmatory factor analysis for goodness of fit (χ2/df = 2.193, SRMR = 0.060, RMSEA = 0.069, GFI = 0.831, CFI = 0.927, NFI = 0.875); (4) Conclusions: The DPET-K was confirmed to be a useful tool for assessing the disaster preparedness of nurses in Korea.
Comparison of the Qualitative and the Quantitative Risk Assessment of Hazardous Substances Requiring Management under the Occupational Safety and Health Act in South Korea
Authors: Moon Hyung-Il , Han Sang-Woo , Shin Saemi , Byeon Sang-Hoon
Published: February 2021

The risk assessment of hazardous substances has become increasingly important for the efficient prevention and management of various diseases or accidents caused by increased amounts of hazardous substances in the workplace. In this study, risk assessment was conducted for 36 kinds of hazardous substances requiring management by using qualitative and quantitative risk assessments. Qualitative risk assessment was performed by multiplying the exposure level class by the hazard class according to the Korea Occupational Safety and Health Agency’s (KOSHA) Chemical Hazard Risk Management (CHARM). The quantitative risk assessment was followed by a four-step risk assessment system presented in the Guidelines for Hazard Risk Assessment of Chemicals (KOSHA GUIDE W-6-2016). In the quantitative assessments, we presented a new method of classifying risk levels into four steps, much like qualitative assessments. In this study, the quantitative risk assessment was considered difficult to predict through qualitative risk assessment. Therefore, it is necessary to perform a quantitative risk assessment after a qualitative risk assessment for a higher level of risk assessment.
Health Risk Assessment of PM2.5 and PM2.5-Bound Trace Elements in Thohoyandou, South Africa
Authors: Edlund Karl Kilbo , Killman Felicia , Molnár Peter , Boman Johan , Stockfelt Leo , Wichmann Janine
Published: February 2021

We assessed the health risks of fine particulate matter (PM2.5) ambient air pollution and its trace elemental components in a rural South African community. Air pollution is the largest environmental cause of disease and disproportionately affects low- and middle-income countries. PM2.5 samples were previously collected, April 2017 to April 2018, and PM2.5 mass determined. The filters were analyzed for chemical composition. The United States Environmental Protection Agency’s (US EPA) health risk assessment method was applied. Reference doses were calculated from the World Health Organization (WHO) guidelines, South African National Ambient Air Quality Standards (NAAQS), and US EPA reference concentrations. Despite relatively moderate levels of PM2.5 the health risks were substantial, especially for infants and children. The average annual PM2.5 concentration was 11 µg/m3, which is above WHO guidelines, but below South African NAAQS. Adults were exposed to health risks from PM2.5 during May to October, whereas infants and children were exposed to risk throughout the year. Particle-bound nickel posed both non-cancer and cancer risks. We conclude that PM2.5 poses health risks in Thohoyandou, despite levels being compliant with yearly South African NAAQS. The results indicate that air quality standards need to be tightened and PM2.5 levels lowered in South Africa.
The Regulator OmpR in Yersinia enterocolitica Participates in Iron Homeostasis by Modulating Fur Level and Affecting the Expression of Genes Involved in Iron Uptake
Authors: Jaworska Karolina , Ludwiczak Marta , Murawska Emilia , Raczkowska Adrianna , Brzostek Katarzyna
Published: February 2021

In this study, we found that the loss of OmpR, the response regulator of the two-component EnvZ/OmpR system, increases the cellular level of Fur, the master regulator of iron homeostasis in Y. enterocolitica. Furthermore, we demonstrated that transcription of the fur gene from the YePfur promoter is subject to negative OmpR-dependent regulation. Four putative OmpR-binding sites (OBSs) were indicated by in silico analysis of the fur promoter region, and their removal affected OmpR-dependent fur expression. Moreover, OmpR binds specifically to the predicted OBSs which exhibit a distinct hierarchy of binding affinity. Finally, the data demonstrate that OmpR, by direct binding to the promoters of the fecA, fepA and feoA genes, involved in the iron transport and being under Fur repressor activity, modulates their expression. It seems that the negative effect of OmpR on fecA and fepA transcription is sufficient to counteract the indirect, positive effect of OmpR resulting from decreasing the Fur repressor level. The expression of feoA was positively regulated by OmpR and this mode of action seems to be direct and indirect. Together, the expression of fecA, fepA and feoA in Y. enterocolitica has been proposed to be under a complex mode of regulation involving OmpR and Fur regulators.
Silk Fibroin as a Functional Biomaterial for Tissue Engineering
Authors: Sun Weizhen , Gregory David Alexander , Tomeh Mhd Anas , Zhao Xiubo
Published: February 2021

Tissue engineering (TE) is the approach to combine cells with scaffold materials and appropriate growth factors to regenerate or replace damaged or degenerated tissue or organs. The scaffold material as a template for tissue formation plays the most important role in TE. Among scaffold materials, silk fibroin (SF), a natural protein with outstanding mechanical properties, biodegradability, biocompatibility, and bioresorbability has attracted significant attention for TE applications. SF is commonly dissolved into an aqueous solution and can be easily reconstructed into different material formats, including films, mats, hydrogels, and sponges via various fabrication techniques. These include spin coating, electrospinning, freeze drying, physical, and chemical crosslinking techniques. Furthermore, to facilitate fabrication of more complex SF-based scaffolds with high precision techniques including micro-patterning and bio-printing have recently been explored. This review introduces the physicochemical and mechanical properties of SF and looks into a range of SF-based scaffolds that have been recently developed. The typical TE applications of SF-based scaffolds including bone, cartilage, ligament, tendon, skin, wound healing, and tympanic membrane, will be highlighted and discussed, followed by future prospects and challenges needing to be addressed.
Influence of Gas Annealing on Sensitivity of AlN/4H-SiC-Based Temperature Sensors
Authors: Jung Seung-Woo , Shin Myeong-Cheol , Schweitz Michael A. , Oh Jong-Min , Koo Sang-Mo
Published: February 2021

In this study, the physical and electrical characteristics of an AlN/4H-SiC Schottky barrier diode-based temperature sensor annealed in various gas atmospheres were investigated. An aluminum nitride (AlN) thin film was deposited on a 4H-SiC substrate via radio-frequency sputtering followed by annealing in N2 or O2 gas. The chemical composition of the film was determined by X-ray photoelectron spectroscopy (XPS) before and after annealing, and its electrical properties were evaluated by plotting a current–voltage (I–V) curve. The voltage–temperature (V–T) characteristics of the sensor were extracted from the current–voltage–temperature (I–V–T) plots constructed in the temperature range between 475 and 300 K in steps of 25 K. Sensitivities of 9.77, 9.37, and 2.16 mV/K were obtained for the as-grown, N2-annealed, and O2-annealed samples, respectively.
4H-SiC Drift Step Recovery Diode with Super Junction for Hard Recovery
Authors: Yan Xiaoxue , Liang Lin , Huang Xinyuan , Zhong Heqing , Yang Zewei
Published: February 2021

Silicon carbide (SiC) drift step recovery diode (DSRD) is a kind of opening-type pulsed power device with wide bandgap material. The super junction (SJ) structure is introduced in the SiC DSRD for the first time in this paper, in order to increase the hardness of the recovery process, and improve the blocking capability at the same time. The device model of the SJ SiC DSRD is established and its breakdown principle is verified. The effects of various structure parameters including the concentration, the thickness, and the width of the SJ layer on the electrical characteristics of the SJ SiC DSRD are discussed. The characteristics of the SJ SiC DSRD and the conventional SiC DSRD are compared. The results show that the breakdown voltage of the SJ SiC DSRD is 28% higher than that of the conventional SiC DSRD, and the dv/dt output by the circuit based on SJ SiC DSRD is 31% higher than that of conventional SiC DSRD. It is verified that the SJ SiC DSRD can achieve higher voltage, higher cut-off current and harder recovery characteristics than the conventional SiC DSRD, so as to output a higher dv/dt voltage on the load.
A Study on Machining Performances of Micro-Drilling of Multi-Directional Carbon Fiber Reinforced Plastic (MD-CFRP) Based on Nano-Solid Dry Lubrication Using Graphene NanoPlatelets
Authors: Kim Jin Woo , Nam Jungsoo , Jeon Jaehun , Lee Sang Won
Published: February 2021

The objective of this study is to investigate the tribological behavior of graphene nanoplatelets (xGnPs) as nano-solid lubricants, and to evaluate their applicability to the micro-drilling of multi-directional carbon fiber-reinforced plastic (MD-CFRP). To verify the tribological effect of nano-solid lubricants, three kinds of xGnPs (xGnP C-750, xGnP M-5, and xGnP H-5), multiwall carbon nanotubes (MWCNTs), and hBN are compared by the ball-on-plate test. Of these, three xGnPs are selected as nano-solid lubricants to investigate the micro-drilling performance of MD-CFRP using nano-solid dry lubrication, and the experimental results demonstrate that all xGnPs can enhance lubrication action in terms of surface quality (delamination, uncut fiber, and inner surface) and tool wear. In particular, larger graphene nanoplatelets (xGnP M-5 and xGnP H-5) are superior to the smaller one (xGnP C-750) by guaranteeing enhanced sliding action between the tool grain and the CFRP composite.
Strength Parameters of Foamed Geopolymer Reinforced with GFRP Mesh
Authors: Krzywoń Rafał , Dawczyński Szymon
Published: February 2021

The foaming of geopolymers lowers their density, thus opening up new environmental benefits, including acoustic and thermal insulation. At the same time, foaming disturbs the homogeneity of the material, which worsens the strength parameters, and particularly those related to tension, which can be improved by introducing reinforcement. This paper presents the results of research on foamed geopolymers reinforced with glass fiber meshes, a type of reinforcement that provides an adequate bond. The samples tested here were based on three types of coal fly ash, and were foamed with varying doses of hydrogen peroxide. Samples were cured at 40 °C and were tested after 28 days of maturing at ambient temperature. The strength parameters of the synthesized geopolymers were determined via laboratory testing, and were used to evaluate load-bearing capacity models of the tested samples reinforced with glass fiber mesh. The results showed the importance of the type of ash on the strength properties and efficiency of reinforcement. At the same time, a slight deterioration in the glass fibers was noticed; this was caused by the presence of sodium hydroxide solution, which was used as an activator.
Which Traits of Humic Substances Are Investigated to Improve Their Agronomical Value?
Authors: Jung Heejung , Kwon Sumin , Kim Jae-Hwan , Jeon Jong-Rok
Published: February 2021

Humic substances (HSs) are chromogenic organic assemblies that are widespread in the environment, including soils, oceans, rivers, and coal-related resources. HSs are known to directly and indirectly stimulate plants based on their versatile organic structures. Their beneficial activities have led to the rapid market growth of agronomical HSs. However, there are still several technical issues and concerns to be addressed to advance sustainable agronomical practices for HSs and allow growers to use HSs reliably. First, it is necessary to elucidate the evident structure (component)–function relationship of HSs. Specifically, the core structural features of HSs corresponding to crop species, treatment method (i.e., soil, foliar, or immersion applications), and soil type-dependent plant stimulatory actions as well as specific plant responses (e.g., root genesis and stress resistance) should be detailed to identify practical crop treatment methodologies. These trials must then be accompanied by means to upgrade crop marketability to help the growers. Second, structural differences of HSs depending on extraction sources should be compared to develop quality control and assurance measures for agronomical uses of HSs. In particular, coal-related HSs obtainable in bulk amounts for large farmland applications should be structurally and functionally distinguishable from other natural HSs. The diversity of organic structures and components in coal-based HSs must thus be examined thoroughly to provide practical information to growers. Overall, there is a consensus amongst researchers that HSs have the potential to enhance soil quality and crop productivity, but appropriate research directions should be explored for growers’ needs and farmland applications.
Nuclear Magnetic Resonance Metabolomics Approach for the Analysis of Major Legume Sprouts Coupled to Chemometrics
Authors: Farag Mohamed A. , Sharaf El-Din Mohamed G. , Selim Mohamed A. , Owis Asmaa I. , Abouzid Sameh F. , Porzel Andrea , Wessjohann Ludger A. , Otify Asmaa
Published: February 2021

Legume sprouts are a fresh nutritive source of phytochemicals of increasing attention worldwide owing to their many health benefits. Nuclear magnetic resonance (NMR) was utilized for the metabolite fingerprinting of 4 major legume sprouts, belonging to family Fabaceae, to be exploited for quality control purposes. Thirty-two metabolites were identified belonging to different classes, i.e., fatty acids, sugars, amino acids, nucleobases, organic acids, sterols, alkaloids, and isoflavonoids. Quantitative NMR was employed for assessing the major identified metabolite levels and multivariate data analysis was utilized to assess metabolome heterogeneity among sprout samples. Isoflavones were detected exclusively in Cicer sprouts, whereas Trigonella was characterized by 4-hydroxyisoleucine. Vicia sprouts were distinguished from other legume sprouts by the presence of L-Dopa versus acetate abundance in Lens. A common alkaloid in all sprouts was trigonelline, detected at 8–25 µg/mg, suggesting its potential role in legume seeds’ germination. Trigonelline was found at highest levels in Trigonella sprouts. The aromatic NMR region data (δ 11.0–5.0 ppm) provided a better classification power than the full range (δ 11.0–0.0 ppm) as sprout variations mostly originated from secondary metabolites, which can serve as chemotaxonomic markers.
Effective and Sustained Control of Soil-Borne Plant Diseases by Biodegradable Polyhydroxybutyrate Mulch Films Embedded with Fungicide of Prothioconazole
Authors: Chen Ge , Cao Lidong , Cao Chong , Zhao Pengyue , Li Fengmin , Xu Bo , Huang Qiliang
Published: February 2021

Soil-borne diseases and plant rhizosphere nematode have caused many crop yield losses. Increased environmental awareness is leading to more restrictions on the use of certain fumigants and root irrigation methods due to their impact on human health and soil system. Therefore, it is necessary to find alternative treatments to maintain crop economic yields and environmental sustainability. In the present work, biodegradable antifungal mulches were prepared by blending poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (PHB) with fungicide of prothioconazole (PRO), which were used for effective and sustained control of soil-borne plant diseases. To reveal the application prospect of the PHB/PRO composite films in the management of soilborne plant diseases, some physical and biological properties were evaluated. The proper mulch film of PHB/PRO was assessed based on its mechanical and optical properties, while water solubility and the film micromorphology was further characterized. The release patterns of composite films under different pH levels were investigated. Moreover, the in vitro antifungal bioassay and pot experiment showed satisfactory bioactivity of the PHB/PRO films against Sclerotium rolfsii Sacc., a soil-borne disease in peanut fields. This study demonstrated that the biodegradable mulch films containing PRO fungicide are capable of inhibiting soil-borne plant pathogenic fungi effectively, and this facile but powerful strategy may find wide applicability in sustainable plant and horticulture protection.
Microfluidic Preparation of 89Zr-Radiolabelled Proteins by Flow Photochemistry
Authors: Earley Daniel F. , Guillou Amaury , van der Born Dion , Poot Alex J. , Holland Jason P.
Published: February 2021

89Zr-radiolabelled proteins functionalised with desferrioxamine B are a cornerstone of diagnostic positron emission tomography. In the clinical setting, 89Zr-labelled proteins are produced manually. Here, we explore the potential of using a microfluidic photochemical flow reactor to prepare 89Zr-radiolabelled proteins. The light-induced functionalisation and 89Zr-radiolabelling of human serum albumin ([89Zr]ZrDFO-PEG3-Et-azepin-HSA) was achieved by flow photochemistry with a decay-corrected radiochemical yield (RCY) of 31.2 ± 1.3% (n = 3) and radiochemical purity >90%. In comparison, a manual batch photoreactor synthesis produced the same radiotracer in a decay-corrected RCY of 59.6 ± 3.6% (n = 3) with an equivalent RCP > 90%. The results indicate that photoradiolabelling in flow is a feasible platform for the automated production of protein-based 89Zr-radiotracers, but further refinement of the apparatus and optimisation of the method are required before the flow process is competitive with manual reactions.
The Influence of Hydrolytic Enzymes on Tannin Adsorption-Desorption onto Grape Cell Walls in a Wine-Like Matrix
Authors: Osete-Alcaraz Andrea , Gómez-Plaza Encarna , Martínez-Pérez Pilar , Weiller Florent , Schückel Julia , Willats William G.T. , Moore John P. , Ros-García José M. , Bautista-Ortín Ana B.
Published: February 2021

This study evaluates the capacity of four hydrolytic enzymes to limit the interactions between grape cell-walls and tannins and/or to favor tannin desorption. Adsorption and desorption tests were conducted by mixing a commercial seed tannin with purified skin cell-walls from Syrah grapes, in the presence or absence of hydrolytic enzymes, in a model-wine solution. The effects of the enzymes were evaluated by measuring the tannins in solution by High Performance Liquid Chromatography (HPLC) and the changes in the cell wall polysaccharide network by Comprehensive Microarray Polymer Profiling (COMPP) while the polysaccharides liberated from cell walls were analyzed by Size Exclusion Chromatography (SEC). The results showed that the enzymes limited the interaction between tannins and cell walls, especially cellulase, pectinase and xylanase, an effect associated with the cell wall structural modifications caused by the enzymes, which reduced their capacity to bind tannins. With regards to the tannin desorption process, enzymes did not play a significant role in liberating bound tannins. Those enzymes that showed the highest effect in limiting the adsorption of tannins and in disorganizing the cell wall structure, cellulase and pectinase, did not lead to a desorption of bound tannins, although they still showed a capacity of affecting cell wall structure. The results indicate that enzymes are not able to access those polysaccharides where tannins are bound, thus, they are not a useful tool for desorbing tannins from cell walls. The practical importance implications of these findings are discussed in the manuscript.
Assessing Health-Related Quality of Life in Children with Coeliac Disease: The Italian Version of CDDUX
Authors: Crocco Marco , Calvi Angela , Gandullia Paolo , Malerba Federica , Mariani Anthea , Di Profio Sonia , Tappino Barbara , Bonassi Stefano
Published: February 2021

We aimed to assess Health-Related Quality of Life (HRQoL) of Italian children and their parents with coeliac disease (CD) using the Coeliac Disease Dutch Questionnaire (CDDUX). The CDDUX underwent a cross-cultural adaptation in a multi-step process, according to international guidelines. A total of 224 children aged between 8–18 years and their parents were prospectively recruited. Cronbach α coefficient was determined as a measure of internal consistency of the questionnaire and inter-children/parent reliability by intraclass correlation coefficient. Univariate and bivariate regression models were used to evaluate correlations between clinical variables and children and parents subclasses of CDDUX and overall mean Paediatric Quality of Life Inventory (PedsQL). The Italian CDDUX proved to be valid and reliable, mean CDDUX total score revealing a neutral evaluation of the quality of life in children 52.6 ± 17.2 and parents 49.5 ± 17.9 (p = 0.07) with strong correlation with PedsQL. The only clinical variable which appeared to affect significantly quality of life both in children and parents was the lower age. A comparison with our results showed remarkable differences in the HRQoL of populations of various nationalities. The Italian version of the CDDUX questionnaire is a simple and reliable tool for assessing the HRQoL in children and adolescents with CD.
The Triad Mother-Breast Milk-Infant as Predictor of Future Health: A Narrative Review
Authors: Verduci Elvira , Giannì Maria Lorella , Vizzari Giulia , Vizzuso Sara , Cerasani Jacopo , Mosca Fabio , Zuccotti Gian Vincenzo
Published: February 2021

The benefits of human milk for both mother and infant are widely acknowledged. Human milk could represent a link between maternal and offspring health. The triad mother-breast milk-infant is an interconnected system in which maternal diet and lifestyle might have effects on infant’s health outcome. This link could be in part explained by epigenetics, even if the underlining mechanisms have not been fully clarified yet. The aim of this paper is to update the association between maternal diet and human milk, pointing out how maternal diet and lifestyle could be associated with breast-milk composition, hence with offspring’s health outcome.
Efficacy of Popular Diets Applied by Endurance Athletes on Sports Performance: Beneficial or Detrimental? A Narrative Review
Authors: Devrim-Lanpir Aslı , Hill Lee , Knechtle Beat
Published: February 2021

Endurance athletes need a regular and well-detailed nutrition program in order to fill their energy stores before training/racing, to provide nutritional support that will allow them to endure the harsh conditions during training/race, and to provide effective recovery after training/racing. Since exercise-related gastrointestinal symptoms can significantly affect performance, they also need to develop strategies to address these issues. All these factors force endurance athletes to constantly seek a better nutritional strategy. Therefore, several new dietary approaches have gained interest among endurance athletes in recent decades. This review provides a current perspective to five popular diet approaches: (a) vegetarian diets, (b) high-fat diets, (c) intermittent fasting diets, (d) gluten-free diet, and (e) low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diets. We reviewed scientific studies published from 1983 to January 2021 investigating the impact of these popular diets on the endurance performance and health aspects of endurance athletes. We also discuss all the beneficial and harmful aspects of these diets, and offer key suggestions for endurance athletes to consider when following these diets.
Visual Acuity Gain Profiles and Anatomical Prognosis Factors in Patients with Drug-Naive Diabetic Macular Edema Treated with Dexamethasone Implant: The NAVEDEX Study
Authors: Pinto Mauricio , Mathis Thibaud , Massin Pascale , Akesbi Jad , Lereuil Théo , Voirin Nicolas , Matonti Frédéric , Fajnkuchen Franck , Conrath John , Milazzo Solange , Korobelnik Jean-François , Baillif Stéphanie , Denis Philippe , Creuzot-Garcher Catherine , Srour Mayer , Dupas Bénédicte , Sudhalkar Aditya , Bilgic Alper , Tadayoni Ramin , Souied Eric H , Dot Corinne , Kodjikian Laurent
Published: February 2021

The purpose of this study is to evaluate the visual acuity (VA) gain profiles between patients with drug-naive diabetic macular edema (DME) treated by dexamethasone implant (DEX-implant) and assess the baseline anatomical and functional factors that could influence the response to the treatment in real-life conditions. A retrospective, multi-center observational study included 129 eyes with drug-naive DME treated by DEX-implant. The Median follow-up was 13 months. Two groups of VA gain trajectories were identified—Group A, with 71% (n = 96) of patients whose average VA gain was less than five letters and Group B, with 29% (n = 33) of patients with an average gain of 20 letters. The probability of belonging to Group B was significantly higher in patients with baseline VA < 37 letters (p = 0.001). Ellipsoid zone alterations (EZAs) or disorganization of retinal inner layers (DRILs) were associated with a lower final VA (53.0 letters versus 66.4, p = 0.002) but without a significant difference in VA gain (4.9 letters versus 6.8, p = 0.582). Despite a low baseline VA, this subgroup of patients tends to have greater visual gain, encouraging treatment with DEX-implant in such advanced-stage disease. However, some baseline anatomic parameters, such as the presence of EZAs or DRILs, negatively influenced final vision.
Nebuliser Type Influences Both Patient-Derived Bioaerosol Emissions and Ventilation Parameters during Mechanical Ventilation
Authors: Joyce Mary , McGrath James A. , Mac Giolla Eain Marc , O’Sullivan Andrew , Byrne Miriam , MacLoughlin Ronan
Published: February 2021

COVID-19 may lead to serious respiratory complications which may necessitate ventilatory support. There is concern surrounding potential release of patient-derived bioaerosol during nebuliser drug refill, which could impact the health of caregivers. Consequently, mesh nebulisers have been recommended by various clinical practice guidelines. Currently, there is a lack of empirical data describing the potential for release of patient-derived bioaerosol during drug refill. This study examined the release of simulated patient-derived bioaerosol, and the effect on positive end expiratory pressure during nebuliser refill during mechanical ventilation of a simulated patient. During jet nebuliser refill, the positive end expiratory pressure decreased from 4.5 to 0 cm H2O. No loss in pressure was noted during vibrating mesh nebuliser refill. A median particle number concentration of 710 particles cm−3 above ambient was detected when refilling the jet nebuliser in comparison to no increase above ambient detected when using the vibrating mesh nebuliser. The jet nebuliser with the endotracheal tube clamped resulted in 60 particles cm−3 above ambient levels. This study confirms that choice of nebuliser impacts both the potential for patient-derived bioaerosol release and the ability to maintain ventilator circuit pressures and validates the recommended use of mesh nebulisers during mechanical ventilation.
On the Path of the Prophet in Unsettled Times: Sudan’s Republican Brotherhood Looks Abroad
Authors: Howard Steve
Published: February 2021

Mahmoud Mohamed Taha (1909–1985) founded the Republican Brotherhood in the early 1950s to promote social reform through a new understanding of divine revelation which had emerged during his two years of khalwa or retreat. From the 1950s through the 1970s, the Republican Brotherhood attracted a few thousand followers to Ustadh Mahmoud’s teachings, whose foundation was the discipline of tariq Mohamed, “the Path of the Prophet.” This Path was a challenging design for life that embraced gender equality and social justice against the backdrop of an increasingly Islamist-oriented Sudan. In the 1980s, the height of the Brotherhood’s membership, the Republicans confronted Sudan President Gaafar Nimeiry’s imposition of his version of “Islamic Law,” with publications and street corner lectures. Through peaceful protest, the Republican’s point was that Islamic Law would only be oppressive to the millions of non-Muslims in the country and to women. The result of this resistance was the 1985 arrest and execution of Taha for trumped-up charges of apostasy. In the decades following the passing of their teacher, the Republicans have kept a low profile in Sudan while trying to maintain both their faith and some social cohesion. In reaction to both the Islamist political conditions in Sudan and the failing economy, many Republicans have joined the Sudanese flight abroad, with modest communities of Republicans now established in the Gulf States of Qatar and UAE, as well as the United States. Through field work and interviews with members of these three communities, I have tried to understand the effort to sustain the discipline of the Path of the Prophet by Republican brothers and sisters under circumstances of the extremist orientations of Gulf politics, or the “moral ambiguity” of the United States. This study is part of a larger book project on the Republican Brotherhood following the execution of Ustadh Mahmoud.
Downscaling Groundwater Storage Data in China to a 1-km Resolution Using Machine Learning Methods
Authors: Zhang Jianxin , Liu Kai , Wang Ming
Published: February 2021

High-resolution and continuous hydrological products have tremendous importance for the prediction of water-related trends and enhancing the capability for sustainable water resources management under climate change and human impacts. In this study, we used the random forest (RF) and extreme gradient boosting (XGBoost) methods to downscale groundwater storage (GWS) from 1° (~110 km) to 1 km by downscaling Gravity Recovery and Climate Experiment (GRACE) and Global Land Data Assimilation System (GLDAS) data from 1° (~110 km) and 0.25° (~25 km) respectively, to 1 km for China. Three evaluation metrics were employed for the testing dataset for 2004−2016: The R2 ranged from 0.77−0.89 for XGBoost (0.74−0.86 for RF), the correlation coefficient (CC) ranged from 0.88−0.94 for XGBoost (0.88−0.93 for RF) and the root-mean-square error (RMSE) ranged from 0.37−2.3 for XGBoost (0.4−2.53 for RF). The R2 of the XGBoost models for GLDAS was 0.64−0.82 (0.63−0.82 for RF), the CC was 0.80−0.91 (0.80−0.90 for RF) and the RMSE was 0.63−1.75 (0.63−1.77 for RF). The downscaled GWS derived from GRACE and GLDAS were validated using in situ measurements by comparing the time series variations and the downscaled products maintained the accuracy of the original data. The interannual changes within 9 river basins between pre- and post-downscaling were consistent, emphasizing the reliability of the downscaled products. Ultimately, annual downscaled TWS, GLDAS and GWS products were provided from 2004 to 2016, providing a solid data foundation for studying local GWS changes, conducting finer-scale hydrological studies and adapting water resources management and policy formulation to local condition.
Earth Observation-Informed Risk Maps of the Lyme Disease Vector Ixodes scapularis in Central and Eastern Canada
Authors: Kotchi Serge Olivier , Bouchard Catherine , Brazeau Stéphanie , Ogden Nicholas H.
Published: February 2021

Climate change is facilitating the geographic range expansion of populations of the tick vector of Lyme disease Ixodes scapularis in Canada. Here, we characterize and map the spatio-temporal variability of environments suitable for I. scapularis using Earth observation (EO) data. A simple algorithm for I. scapularis occurrence (cumulative degree-days and forest: CSDF) was developed by combining cumulative annual surface degree-days above 0 °C and forest cover. To map the environmental risk of I. scapularis (risk of I. scapularis: RIS) in central and eastern Canada from 2000 to 2015, CSDF was adjusted using data from an I. scapularis population model. CSDF was validated using cumulative annual degree days >0 °C (CADD) from meteorological stations, and CSDF was strongly associated with CADD (n = 52, R2 > 0.86, p < 0.001). Data on field surveillance for I. scapularis ticks (2008 to 2018) were used to validate the risk maps. The presence of I. scapularis ticks was significantly associated with CSDF, and at a limit of 2800, sensitivity approached 100%. RIS increased over the study period, with the highest values in 2012 and the lowest in 2000. The RIS was on average higher in Ontario and Quebec compared to other provinces, and it was higher in the southern parts of the provinces. The proportion of the populated areas with a positive RIS increased on average in central and eastern Canada from 2000 to 2015. Predicted I. scapularis occurrence identifies areas with a more probable risk of tick bites, Lyme disease, and other I. scapularis-borne diseases, which can help guide targeted surveillance, prevention, and control interventions.
Remote Sensing and Machine Learning in Crop Phenotyping and Management, with an Emphasis on Applications in Strawberry Farming
Authors: Zheng Caiwang , Abd-Elrahman Amr , Whitaker Vance
Published: February 2021

Measurement of plant characteristics is still the primary bottleneck in both plant breeding and crop management. Rapid and accurate acquisition of information about large plant populations is critical for monitoring plant health and dissecting the underlying genetic traits. In recent years, high-throughput phenotyping technology has benefitted immensely from both remote sensing and machine learning. Simultaneous use of multiple sensors (e.g., high-resolution RGB, multispectral, hyperspectral, chlorophyll fluorescence, and light detection and ranging (LiDAR)) allows a range of spatial and spectral resolutions depending on the trait in question. Meanwhile, computer vision and machine learning methodology have emerged as powerful tools for extracting useful biological information from image data. Together, these tools allow the evaluation of various morphological, structural, biophysical, and biochemical traits. In this review, we focus on the recent development of phenomics approaches in strawberry farming, particularly those utilizing remote sensing and machine learning, with an eye toward future prospects for strawberries in precision agriculture. The research discussed is broadly categorized according to strawberry traits related to (1) fruit/flower detection, fruit maturity, fruit quality, internal fruit attributes, fruit shape, and yield prediction; (2) leaf and canopy attributes; (3) water stress; and (4) pest and disease detection. Finally, we present a synthesis of the potential research opportunities and directions that could further promote the use of remote sensing and machine learning in strawberry farming.
Intelligent Control Method of Hoisting Prefabricated Components Based on Internet-of-Things
Authors: Zhao Yuhong , Cao Cunfa , Liu Zhansheng , Mu Enyi
Published: February 2021

Prefabricated buildings are widely used because of their green environmental protection and high degree of industrialization. However, in construction process, there are some defects such as small wireless network coverage, high-energy consumption, inaccurate control, and backward blind hoisting methods in the hoisting process of prefabricated components (PC). Internet-of-Things (IoT) technology can be used to collect and transmit data to strengthen the management of construction sites. The purpose of this study was to establish an intelligent control method in the construction and hoisting process of PC by using IoT technology. Long Range Radio (LoRa) technology was used to conduct data terminal acquisition and wireless transmission in the construction site. The Inertial Measurement Unit (IMU), Global Positioning System (GPS), and other multi-sensor fusion was used to collect information during the hoisting process of PC, and multi-sensor information was fused by fusion location algorithm for location control. Finally, the feasibility of this method was verified by a project as a case. The results showed that the IoT technology can strengthen the management ability of PC in the hoisting process, and improve the visualization level of the hoisting process of PC. Analysis of the existing outdated PC hoisting management methods, LoRa, IMU, GPS and other sensors were used for data acquisition and transmission, the PC hoisting multi-level management and intelligent control.
The Combination of Building Greenery and Photovoltaic Energy Production—A Discussion of Challenges and Opportunities in Design
Authors: Zluwa Irene , Pitha Ulrike
Published: February 2021

In the case of building surfaces, the installation of green roofs or green facades can be used to reduce the temperature of the environment and the building. In addition, introducing photovoltaic energy production will help to reduce CO2 emissions. Both approaches (building greenery and photovoltaic energy production) compete, as both of them are located on the exterior of buildings. This paper aims to give an overview of solutions for the combination of building greenery (BG) systems and photovoltaic (PV) panels. Planning principles for different applications are outlined in a guideline for planning a sustainable surface on contemporary buildings. A comprehensive literature review was done. Identified solutions of combinations were systematically analysed and discussed in comparison with additional relevant literature. The main findings of this paper were: (A) BG and PV systems with low sub-construction heights require shallow substrates/low growing plants, whereas in the case of the combination of (a semi)-intensive GR system, a distance of a minimum 60 cm between the substrate surface and lower panel edge is recommended; (B) The cooling effect of the greenery depends on the distance between the PV and the air velocity; (C) if the substrate is dry, there is no evapotranspiration and therefore no cooling effect; (D) A spectrum of different PV systems, sub-constructions, and plants for the combination of BG and PV is necessary and suitable for different applications shown within the publication.
Dynamics of Soil Organic Carbon and Labile Carbon Fractions in Soil Aggregates Affected by Different Tillage Managements
Authors: Shen Xiaolin , Wang Lili , Yang Qichen , Xiu Weiming , Li Gang , Zhao Jianning , Zhang Guilong
Published: February 2021

Our study aimed to provide a scientific basis for an appropriate tillage management of wheat-maize rotation system, which is beneficial to the sustainable development of agriculture in the fluvo-aquic soil areas in China. Four tillage treatments were investigated after maize harvest, including rotary tillage with straw returning (RT), deep ploughing with straw returning (DP), subsoiling with straw returning (SS), and no tillage with straw mulching (NT). We evaluated soil organic carbon (SOC), dissolved organic carbon (DOC), permanganate oxidizable carbon (POXC), microbial biomass carbon (MBC), and particulate organic carbon (POC) in bulk soil and soil aggregates with five particle sizes (>5 mm, 5–2 mm, 2–1 mm, 1–0.25 mm, and <0.25 mm) under different tillage managements. Results showed that compared with RT treatment, NT treatment not only increased soil aggregate stability, but also enhanced SOC, DOC, and POC contents, especially those in large size macroaggregates. DP treatment also showed positive effects on soil aggregate stability and labile carbon fractions (DOC and POXC). Consequently, we suggest that no tillage or deep ploughing, rather than rotary tillage, could be better tillage management considering carbon storage. Meanwhile, we implied that mass fractal dimension (Dm) and POXC could be effective indicators of soil quality, as affected by tillage managements.
Simulation, Optimization, and Machine Learning in Sustainable Transportation Systems: Models and Applications
Authors: de la Torre Rocio , Corlu Canan G. , Faulin Javier , Onggo Bhakti S. , Juan Angel A.
Published: February 2021

The need for effective freight and human transportation systems has consistently increased during the last decades, mainly due to factors such as globalization, e-commerce activities, and mobility requirements. Traditionally, transportation systems have been designed with the main goal of reducing their monetary cost while offering a specified quality of service. During the last decade, however, sustainability concepts are also being considered as a critical component of transportation systems, i.e., the environmental and social impact of transportation activities have to be taken into account when managers and policy makers design and operate modern transportation systems, whether these refer to long-distance carriers or to metropolitan areas. This paper reviews the existing work on different scientific methodologies that are being used to promote Sustainable Transportation Systems (STS), including simulation, optimization, machine learning, and fuzzy sets. This paper discusses how each of these methodologies have been employed to design and efficiently operate STS. In addition, the paper also provides a classification of common challenges, best practices, future trends, and open research lines that might be useful for both researchers and practitioners.