bluuebunny/crossref_metadata_2025 huggingface dataset:
GLUCOREGULATORY ACTIONS OF INCRETINS/ANTI-INCRETINS
Authors: ShikhaaMahajan Dr.
Published: June 2024

Diabetes mellitus (DM) is a chronic debilitating and non-communicable disease characterized by chronic hyperglycemia and resulting from a defect in insulin secretion, insulin action, or both. Apart from these, defective actions of the gastrointestinal (GI) incretin hormones: glucagon-like peptide–1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) also play significant roles in it. Incretins are gut hormones that potentiate insulin secretion after meal ingestion in a glucose-dependent manner. In Type 2 Diabetes Mellitus (T2DM) the insulinotropic effect of incretins is deficient. Recognition and a better understanding of the role of the incretins and the enzyme involved in their degradation have led to the development of two incretin-based treatments: the GLP-1 receptor agonists, which possess many of the glucoregulatory actions of incretin peptides, and the dipeptidyl peptidase- IV (DPP-4) inhibitors. Incretin-based therapies are promising tools for the management of T2DM, especially in overweight and obese individuals and have revolutionized the medical management of T2DM in the 21st century. The outcome of certain types of bariatric surgery that result in rapid amelioration of glucose tolerance, lead to conclude that dopamine serves as an “anti-incretin” signal that counterbalances the stimulatory effect of GLP-1. The kinetics of release of GLP-1 and dopamine suggests the existence of a second (gut-based) layer of regulation of glucose homeostasis. The idea of a second layer of regulation of glucose homeostasis originates in the foregut and hindgut hypotheses posited to explain the effects of bariatric surgery on T2DM. Dopaminergic negative feedback acting on insulin secretion is active in beta-cells. Importantly, blocking this dopaminergic feedback increases insulin secretion. Therefore, the Dopamine receptor, or one of the steps downstream of its activation, is a potential target for new drugs to treat T2DM.
SYNBIOTICS: A NOVEL APPROACH IN MANAGING ORAL DISEASES
Authors: Mohapatra Dr. Subhashree , Mohandas Dr. Rahul
Published: June 2024

The desire for natural alternatives has increased as a result of the usage of antibiotics, which has caused pathogenic organisms to exhibit skyrocketing levels of multidrug resistance. Clinical evidence demonstrating the usefulness and effectiveness of several prebiotics and probiotic strains in enhancing oral health has increased over the last few years. It has recently been suggested that combining prebiotics and probiotics may result in the development of novel synbiotics that may function well in the fight against oral bacteria. According to the FAO/WHO (2001), probiotics are described as live microbes that boost the host’s health when given in sufficient quantity. According to Gibson and Roberfroid (1995), prebiotics are described as non-digestible food ingredient that beneficially affects the host by selectively stimulating the growth and/or activity of one or a limited number of bacteria in the colon, and thereby improves host health Mixtures of probiotics and prebiotics that beneficially affect the host by enhancing the survival and implantation of live microbial dietary supplements are referred to as "synbiotics." The creation of synbiotics may have a positive synergistic impact on oral health and make up for the shortcomings of the individual components. This article has reviewed the most recent information on the function of synbiotics in preserving oral health, recommendations, and potential future applications.
DIAGNOSIS AND TREATMENT PLANNING FOR DENTAL IMPLANTS
Authors: Pandey Prof Ashish
Published: June 2024

Diagnosis and treatment planning for dental implants represent the foundational pillars upon which successful implant procedures are built. These essential steps involve a meticulous and comprehensive assessment of a patient's unique oral and medical conditions, followed by the creation of a tailored roadmap for implant placement. In this intricate process, healthcare professionals meticulously evaluate a multitude of factors, ranging from the patient's medical history and dental health to bone quality, prosthodontic needs, and potential risks.
TOBACCO: POISONING, ADDICTION AND DE-ADDICTION – AYURVEDA AND CONTEMPORARY PERSPECTIVE
Authors: P. Adhao Dr. Mamata
Published: June 2024

Tambhakhu (Tobacco) are the leaves of the tobacco plant (Nicotiana Tabacum), termed as Tamraparn in Ayurveda. It contains toxic alkaloids, the principal alkaloid being Nicotine present in one to eight percent. Tobacco is the highly consumed psychotropic drug worldwide. Tobacco can be consumed in various forms that is- sniffing, chewing, smoking or dipping. It is more addictive than cocaine and heroin and acts as a mood leveler, resulting in emotional dependence. Tobacco poisoning can occur by absorption either through intact or broken skin,by inhalation or ingestion. Nicotine first stimulates, then depresses, and later paralyses autonomic ganglia, brain and skeletal muscles. According to Ayurveda the properties of tobacco are similar to poison. The adverse effects or overdosing effects are noted as- Bhramaka (Induces vertigo), Madakarit (narcotic), Drishtimandyatwa (blindness). The Circumstances of tobacco poisoning mainly occurs through accidental poisoning while suicidal and homicidal poisoning is rare. Tobacco consumption gradually blocks economic, personal and social development. In order to quit this habit it is recommended to gradually reduce tobacco use instead of abruptly stopping. An organized plan for de-addiction includes three phases Assessment, Intervention and Follow up. It is the duty of every Physician, National authorities and a Responsible citizen to create awareness about the destructive effects of tobacco consumption.
RECENT ADVANCES IN PROSTHODONTICS
Authors: Wankhade Dr. Sushant , S. Barabde Dr. Aparna , Dammani Dr. Brajesh , Warghane Dr. Komal , Pethe Dr. Pallavi , Kamble Dr. Neelima
Published: June 2024

Dentistry has advanced well beyond tooth replacement to include the repair of lost alveolar components that support facial characteristics, aesthetic restoration, speech improvement, and a variety of other key breakthroughs. Most importantly, by combining artificial materials and cutting-edge technologies, dentistry can now provide a surprisingly lifelike appearance, demonstrating one of the pinnacles of human achievement. Prosthodontics progresses at a quick speed, not just in response to scientific developments, but also as a result of societal influences such as consumerism. In order to fulfil these desires, it is our duty to be updated with both knowledge and skills about new trends in prosthodontics, so that these aspirations can be met with. This chapter gives an insight about the various trends and concepts applied in the field of prosthodontics.
ARTIFICIAL INTELLIGENCE AND ITS APPLICATION IN SLEEP MEDICINE
Authors: Rai Anushree , Aditi Ms.
Published: June 2024

Recent years have seen tremendous progress in the field of sleep medicine, and the use of artificial intelligence (AI) has been crucial in improving the diagnostic and therapeutic elements of sleep-related illnesses. This chapter examines the several uses of artificial intelligence (AI) in sleep medicine, highlighting how this technology has the potential to completely change how sleep disorders are identified, tracked, and managed. The establishment of sophisticated monitoring systems is a key use of AI in sleep medicine. The integration of AI algorithms with wearable devices and non-intrusive sensors allows for the remote and continuous monitoring of sleep patterns. Because these devices offer real-time feedback, abnormalities can be identified and treatment regimens can be modified in a timely manner. In conclusion, AI-enabled improvements in diagnosis, monitoring, and therapy not only boost healthcare delivery efficiency but also open the door to more individualised and patient-centered approaches to the management of sleep-related illnesses. The combination of artificial intelligence with sleep medicine has the potential to significantly improve sleep health and general quality of life as technology advances.
AI IN DENTAL PRACTICE
Authors: Singh Priya , Aggarwal Juhi
Published: June 2024

Artificial intelligence (AI) has grown dramatically in importance and use across many industries, including dentistry. In the healthcare sector, particularly in endodontics, artificial intelligence can replicate human intelligence effectively, enabling it to make intricate predictions and informed decisions. In the field of endodontics, convolutional neural networks and/or artificial neural networks have demonstrated numerous applications. These include studying the intricate anatomy of the root canal system, accurately predicting the viability of dental pulp stem cells, precise measurements of working lengths, efficient detection of root fractures and periapical lesions, and providing valuable insights into the potential success of retreatment procedures. These advanced technologies have significantly enhanced diagnostic and decision-making capabilities in endodontic practice. This comprehensive study aims to explore the significant impact of artificial intelligence (AI) technology on dentistry by analyzing vast amounts of data, leading to improved clinical decision-making. The research extensively reviews various stages of clinical dentistry where AI is currently playing a crucial role. A compilation of documents spanning from 1990 to 2022 has been gathered, covering the major topics related to artificial intelligence-assisted dentistry. Through this investigation, the study seeks to shed light on the advancements and potential of AI in enhancing dental practices and patient care.
MICROBIAL PATHOGENESIS OF ULCERATIVE COLITIS
Authors: Mishra Dr. Ruchi
Published: June 2024

Global increase in inflammatory bowel disease (IBD) may be due to alteration of gut microbiota, changing environmental pattern and its impact, role of genetics and immune response towards foreign bodies. Ulcerative colitis (UC) may be a chronic illness that includes perennial inflammation of the colonic mucous membrane. UC is an inflammatory gastrointestinal disease usually associated with the inner lining of large intestine due to microbial dysbiosis, including bacteria, viruses and fungi. Several major factors are responsible for inducing gut dysbiosis, immune dysregulation which exaggerate the severity of infection. The therapeutic approach of probiotics, prebiotics and antibiotics will be beneficial for the efficacious microbiome manipulation in ulcerative colitis. The treatment goal is to induce a steroid-free recurrence also to prevent complications of the disease at the same time. The treatment depends on the level of severity, localization and the course of the disease. Aminosalicylic acid (5-ASA) compounds are used as first line of treatment. More severe disease should be treated with oral and local application of amino salicylic acid compound; immune modulators and steroidal therapy has been proved more efficacious.
EXPLORING SEMANTIC DIMENSIONS: UNRAVELLING THE COMPLEXITY OF ENGLISH LANGUAGE
Authors: P. Sakthivel Dr.
Published: June 2024

This research article delves into the intricate world of semantics within the English language, aiming to unravel its complexity and shed light on its various dimensions. By employing a comprehensive and interdisciplinary approach, this article investigates the underlying mechanisms that govern meaning and interpretation in English. Through extensive analysis of lexical semantics, semantic relationships, and contextual influences, we uncover the intricate interplay between words, phrases, and sentences. Moreover, this paper examines the impact of cultural, social, and historical factors on semantic evolution and variation. The findings of this study contribute to a deeper understanding of the semantic structure of English, paving the way for advancements in natural language processing, computational linguistics, and language education.
VISUALIZING SHADOWS: EXPLORING CRIME, MEMORY, AND MEDICAL HUMANITIES IN POST-COVID GRAPHIC NOVELS
Authors: Karmakar Debasish
Published: June 2024

The intersection of crime and graphic novels in a post-COVID world provides a captivating lens to explore themes in medical humanities and memory studies. This paper delves into the profound psychological impact of crime, social inequalities, memory and trauma, ethical dilemmas, narrative and representation, and the cultural and historical context of crime through the unique storytelling medium of graphic novels. In the aftermath of a global pandemic, where society grapples with collective trauma, graphic narratives shed light on the intricate experiences of crime's victims and perpetrators, examining their mental health, memory, and sense of self. These narratives also highlight the role of social inequalities in shaping criminal activities and experiences, addressing issues of access to healthcare, economic hardships, and discrimination. Moreover, crime-related graphic novels explore the relationship between memory and trauma, revealing how the pandemic and crime disrupt individual and collective memories, influencing healing, recovery, and the pursuit of justice. Ethical dilemmas surrounding crime and justice become more complex in a post-COVID world with strained healthcare systems and shifting social norms, prompting critical reflection on punishment, rehabilitation, and memory erasure. Graphic novels challenge dominant narratives and offer diverse representations of crime, criminals, and victims, influencing our collective understanding of crime, memory, and healthcare practices. Additionally, these narratives contextualize crime within the broader cultural and historical fabric, examining issues such as surveillance, privacy, and the impact of technology. By exploring this intersection, we gain insights into the psychological, social, ethical, and cultural dimensions of crime, memory, and healthcare in a post-pandemic society. This exploration fosters critical analysis, empathy, and reflection on the complex interactions between individuals, society, and memory, shaping our understanding of the post-COVID world and its implications.
RECONSTRUCTING SHIVA AS THE INDIAN HERO IN AMISH TRIPATHI’S SHIVA TRILOGY
Authors: Soni Dr. Vinita
Published: June 2024

The concept of ‘Heroism’ in many ways is culture specific, in context of the Indian culture the figure of Lord Shiva is one of the most intriguing yet, powerful figures within the annals of Indian mythology. Aim of this chapter is to show Lord Shiva as perfecembodiment of a dynamic ‘hero’ who in the public eye is not only an exceptional warrior but also an epitome of passion who holds the feminine and the supporting figures of his valor with dignified veneration. It also aims at explaining concept of ‘Heroism’ both in terms of the Indian society as well as from the point of view of an evolving reading audience who wishes not to idealize a Hero so removed from their moment in time but to look up to a power figure, who despite having ancient roots has the ability to mirror the contemporary fancies along with all its imperfect magnetism.
UNRAVELLING PHRASEOLOGY: A COMPREHENSIVE STUDY OF ITS VARIATIONS IN MODERN LINGUISTICS
Authors: M Ms. Nikita Subudhi
Published: June 2024

This article explores the intricate field of phraseology, a language subsystem extensively studied in Russian and Uzbek linguistics. Phraseology, encompassing both phraseological units and idioms, plays a crucial role in conveying cultural characteristics within language. The study delves into the stylistic value of these units, emphasizing their impact on understanding the culture, mindset, and traditions of a community. The article also addresses the challenges in classifying and translating phraseological units, highlighting issues related to semantics and cultural nuances. Additionally, it discusses variations in phraseological units and their distinct characteristics, such as content stability, integrity, immediate availability, imagery, and semantic reshaping. In essence, the article underscores how phraseological units serve as linguistic reflections of customs, culture, and national mentality, enriching communication with depth and cultural significance.
INTRODUCTION TO NEUROLINGUITICS AND LINGUISTIC APHASIOLOGY
Authors: Rautara Dr. Sarita , Sahoo Dr. Subhasmita , Dash Dr. Niharika , Sharma Dr. Mukesh
Published: June 2024

Neuroscience is the scientific study involving the nervous system in terms of its function and related disorders, documented by neuroscientists. Neurolinguistic is considered as a smaller part of cognitive neuroscience where the neurolinguist studies the role of brain in the representation and utilization of language acquisition, and process of language development throughout human life. There are several different views and theories from various researchers and Neurolinguists regarding the relationship between brain and language as well as how the brain is affected by diseases impacting language disorders are the concomitant of brain damage. Hence, aphasiology and linguistic aphasiology are taken into consideration as the dominant branches of neurolinguistics.
BUSINESS TRANSFORMATION THROUGH DIGITAL MARKETING
Authors: Gunjan Mr. Amit
Published: June 2024

COVID 19 has shifted the physical world to the digital world. In the world of the machine, they are not in a position to bifurcate between the various users. The bifurcation can be done only with the help of web analytics. With the help of cookies, server log, and page tag we can track the data in a proper way. There are various tools like Google Analytics and Adobe Analytics that can track online data in real-time. We can make our Website more efficient if we are able to analyze the data in the proper way and if we will give recommendation which is effective for the company.
UNLEASHING THE POWER OF TOMORROW'S MANAGEMENT
Authors: R Sowjanya , G Jayanthi Dr.
Published: June 2024

This chapter investigates the management trends that will shape the way organizations are led and operated in the coming years. Traditional management practices are being challenged as technology advances at an unprecedented rate, giving rise to new ideas and strategies. The chapter goes to crucial areas where tomorrow's management will wield influence, such as digital transformation, artificial intelligence, agile techniques, remote work, sustainability, and diversity and inclusion. We acquire insights into how organizations may adapt and exploit emerging technologies and processes to stay competitive and flourish in the rapidly developing business landscape by evaluating these trends. Furthermore, the chapter analyses the ramifications and potential issues that these futuristic trends may bring, such as ethical considerations, cyber security, and the need for worker reskilling and upskilling. Organizations may leverage the potential of tomorrow's management by embracing these developing trends, resulting in innovative and flexible workplaces that thrive in an increasingly interconnected and complicated environment.
IMPACT OF RESPONSIVENESS ON CUSTOMER SATISFACTION CROSS BUYING BEHAVIOUR REVISIT INTENTION AND REFERRAL BEHAVIOUR
Authors: Meenakshi Dr. A. , Saiprasad K.
Published: June 2024

The rapid pace of information technology development was the only factor in the subsequent paradigm shift in cultural norms. Customers began doing more of their purchasing online as opposed to at conventional brick-and-mortar stores. Traditional businesses are using e-commerce as a medium for customer interaction in an effort to gain a competitive edge. Even though the topic of customer satisfaction has been a contentious one in the profession of marketing for more than three decades, there is still no universally accepted definition of it. Customer satisfaction is crucial to an organization's performance since it directly affects how well-satisfied its customers are and how profitable and successful the business is. Many businesses found that it was challenging to establish a strong link between the frequency of repeat purchases and consumer satisfaction; even when they were successful, the link was occasionally shaky. An creative way to address these demands is to adopt a fresh strategy for modifying the concepts of customer value, customer satisfaction, and behavioural objectives to the unique needs of diverse consumer types, as indicated by the manner in which they seek out information. In contrast to clients who were passive, those who were relationally dependent and rationally active showed a higher link between perceived value and contentment as well as a stronger link between satisfaction and behavioural intentions. As opposed to clients who were passive, this.
SUSTAINABLE MANAGEMENT OF CONSTRUCTION AND DEMOLITION WASTE MATERIALS- 4 R STRATEGY (REDUCE, REUSE, RECYCLE AND REBUY)
Authors: Dhull Dr. (Er.) Hardik
Published: June 2024

Waste from construction and demolition (C&D) falls under a subcategory with a low rate of material diversion and a wide range of possible uses for waste materials. The recycled materials have enough strength to be taken into consideration for reapplication in the construction sector. The present waste management system in India has been examined, and the barriers to completing the consumption loop and creating markets for recycled materials have also been tested as part of a study project. Waste reduction would be the waste minimization approach most frequently used in the context of the 4R concept. This shows that the local construction industry has the knowledge required to design the processes involved in waste management, but the execution is still far from ideal. Profits drive the market, and they also encourage building experts to embrace innovative practices.
FUTURE TRENDS IN MARKETING
Authors: Bhagowati Dr. Darshana
Published: June 2024

The marketing concept is the foundation of modern marketing. However, it has evolved to take into account the changing needs of customers and the changing marketplace. Businesses now use a variety of marketing tools and strategies to reach their target customers and satisfy their needs. The marketing concept is a dynamic and evolving field. As the needs of customers and the marketplace change, so too will the marketing concept. However, the basic principles of the marketing concept will remain the same: businesses must identify the needs of the target customers and then develop products and services that satisfy those needs. The chapter strives to impart that the use of technology particularly, the contribution of Artificial Intelligence in today’s marketing process.
SUSTAINABLE MARKETING IN THE LUXURY INDUSTRY
Authors: B.S Mrs. Shashwathi
Published: June 2024

This book chapter explores the integration of sustainability in the luxury industry, with a specific focus on sustainable marketing practices and eco-friendly materials. Luxury brands are adapting to changing consumer perceptions and demands, incorporating eco-conscious initiatives and responsible sourcing into their business models. The evolution of sustainability in luxury is traced, highlighting the challenges faced in maintaining exclusivity while adopting sustainable practices. Eco-friendly materials such as organic textiles, ethical leather, and recycled elements are examined, along with the complexities of sourcing them. Consumer perceptions of sustainable luxury products are analyzed, indicating a growing interest and willingness to pay a premium for environmentally responsible goods. This chapter also delves into the factors influencing consumer behaviour, emphasizing environmental awareness, brand values, and lifestyle aspirations. Overall, this chapter emphasizes the importance of integrating sustainability into the luxury industry to meet the demands of the socially-conscious consumer and build a more responsible future.
SUSTAINABLE AND ETHICAL MANAGEMENT PRACTICES
Authors: N R Mr. Rohith
Published: June 2024

Sustainable and ethical management practices have emerged as crucial components in the modern business landscape. This abstract discusses various aspects of sustainable management, highlighting the significance of environmental stewardship, corporate social responsibility (CSR), ethical leadership, employee engagement, and innovation for sustainable development. Environmental stewardship involves responsible resource management, aiming to reduce the ecological footprint of organizations. By adopting green technologies and circular economy principles, businesses can promote sustainability while achieving cost savings and minimizing environmental impacts. Corporate social responsibility (CSR) focuses on ethical behavior and community engagement. Embracing diversity and inclusivity is vital in addressing social issues and promoting a harmonious workplace culture. Sustainable supply chain management plays a crucial role in sourcing responsibly and ensuring ethical practices throughout the supply chain. Ethical leadership fosters a culture of integrity, guiding employees towards ethical decision-making and behavior. Engaging employees in sustainability and ethics empowers them to actively contribute to responsible business practices. Innovation for sustainable development is essential for addressing global challenges such as climate change and resource depletion. Collaborative efforts and partnerships are instrumental in driving innovation and achieving sustainable goals. While sustainable management offers significant benefits, organizations face challenges such as upfront costs, data measurement complexities, and resistance to change. Adherence to regulations and policies and cooperation along the supply chain are also necessary for successful sustainable management. In conclusion, sustainable and ethical management is not just a social responsibility but a strategic imperative for long-term success. By prioritizing environmental and social aspects, promoting ethical leadership, engaging employees, and fostering innovation, organizations can build a sustainable and equitable future.
RECENT DEVELOPMENT IN ALUMINIUM MMCs: MATERIALS, METHODS AND APPLICATIONS
Authors: Banker Kapil , Dhruv Dr. Prof. Anand B
Published: June 2024

The development of Aluminium MMCs has seen significant improvements in fundamental science and technology. These advancements include gaining a comprehending behaviour of composites, the significance of fibre-matrix interfaces, the importance of surface coatings, diverse manufacturing methods, and thermal-mechanical processing techniques used for MMCs. This knowledge has not only led to the improvement of MMC technology but also paved the way for the expansion of high-temperature inter metallic-MMCs The challenges for lighter materials with improved characteristics for miscellaneous applications has led to the emergence of a novel category of materials called Metal Matrix Composites (MMCs). These composite materials offer excellent physical, mechanical, and developmental properties, making them extensive applications in various industries, including aircraft technology, automotive, defense, electronics, and space. The versatility of MMCs has led to extensive research and development in the field of production technologies, resulting in cost reductions and increased acceptance in the market. The objective of this book chapter is to bring inclusive summary of the present application situation of MMCs and the various production approaches presently employed in their invention. By reviewing the current state of MMC technology and fabrication techniques, the Chapter aims to shed light on the promising potential of MMCs as advanced materials in various industries.
DESIGN AND FABRICATION OF REAPER MACHINE FOR WHEAT AND RICE CROP
Authors: Halde Mr. Yogesh , Mishra Dr. Hredeya
Published: June 2024

The remaining goal of agriculture or farming in India isn't best limited to developing of plants but is likewise associated with the monetary growth of farmers and labours. Small scale farmers regularly face the problem of labour shortage or are unable to find the money for the wages to be paid. It's miles therefore, critical to adopt the mechanical strategies in order that the timeliness in harvesting operation might be ensured .Considering different factors as strength requirement , value of system , ease of operation , field circumstance , time of operation and climatologically conditions. It runs on two stroke petrol engine of 3HP, this energy from engine, is provided via pulley and equipment field arrangement to the cutter. This compact harvester is manufactured the usage of regionally to be had spare elements and as a result, it's far effortlessly maintainable. This harvester is probably the solution to the troubles faced by a small scale farmer regarding fee and labour implementation.
EVOLUTION OF CONCRETE INCORPORATING RICE HUSK ASH
Authors: Pannirselvam N. , Kandasamy S. , Sundararaman S. , Vanjinathan J. , Azhagarsamy S.
Published: June 2024

Concrete, as its name implies, is an eco-friendly solution that contributes to environmental preservation by utilizing industrial byproducts, such as rice husk ash, to create concrete structures that conserve resources. This study investigates the characteristics of rice husk ash when employed as a partial substitute for Portland pozzolana cement within concrete compositions. Substitution ratios of 0% to 30% by weight of rice husk ash for Portland pozzolana cement were considered. Compressive strength tests were conducted on 150mm hardened concrete cubes after 7 and 28 days of water curing. The introduction of rice husk ash to Portland cement notably enhances the concrete's strength. The research further examines the impact of varying proportions of rice husk ash on the physical and mechanical traits of the concrete, evaluated through compressive strength, Young's modulus, and flexural strength measurements. These findings were juxtaposed with those of a control sample to authenticate the feasibility and efficacy of incorporating rice husk ash into the concrete mixture.
INNOVATIVE APPROACHES: PLANT-BASED POLYMERS AND BAMBOO CHIPS AS ADMIXTURES IN MORTAR AND CONCRETE PREPARATIONS
Authors: Dutta Shantanu , Goswami Ghritartha , Borah Pranjit
Published: June 2024

This review paper comprehensively analyzes the use of additives, admixtures, and natural polymers in cement-based materials to enhance performance, durability, and environmental impact. It highlights the potential of incorporating natural extracts, biopolymers, and renewable materials as eco-friendly alternatives to chemical admixtures. The study explores self-healing materials, preventive repair methods, and internal curing with super-absorbent polymers to develop durable and sustainable concrete solutions. The review identifies research gaps and areas for further investigation, emphasizing the need to optimize material combinations and understand compatibility issues. Overall, this study contributes to advancing eco-conscious construction practices and encourages the integration of innovative and sustainable materials in the building industry.
TIME HISTORY ANALYSIS OF WATER TANK WITH FIXED SUPPORT
Authors: Katakpure Madhavi Ganesh , Hemant Dahake Prof. , S. D Ambadkar Dr
Published: June 2024

The tremors are the results of energy exodus from the inner core of the earth that releases the seismic waves. The impact of these waves is enormous on lives, properties and ambient environment as well by virtue of ground shaking and rupture. It is critical to understand the features of ground motion to take precautions against loss of life and structural damage caused by ground motion. Peak ground acceleration (PGA), frequency content, and duration are the most essential dynamic aspects of an earthquake. In examining the behaviour of structures under seismic loads, these properties play a major role. The strength of ground motion is determined by the PGA, frequency content, and duration of the shaking. The frequency content of ground motion varies from low to intermediate to high. The current work is concerned with the investigation of the frequency content of ground motion on a water tank. The structural analysis and design (STAAD Pro) software is used to do linear time history analysis. The suggested method investigates the reaction of a water tank to ground vibrations with fixed and pinned support frequencies.
AN OVERVIEW OF WASTE MATERIALS USED AS SOIL STABILIZERS FOR SUSTAINABLE DEVELOPMENT
Authors: Chatrabhuj Mr. , Meshram Kundan
Published: June 2024

Soil is the base of any construction, so for any construction activity engineers cannot construct their structure on soil of less strength. It becomes very important to stabilize soil so that it can bear the load of the structure and keep the structure safe and sound. There are various waste materials, and rather than disposing of them, they can be used to improve soil strength like CBR, Tri axial, and UCS. This study investigates and analyze, upon mixing that material what are the change in the properties of soil. Various waste materials like Processed E-waste, Fly ash, Plastic Strips, Stone dust, Slag, Rise Husk, Bottom ash, Bagasse Ash, Coir fiber, Waste Tyre chips, Waste Glass, Sewage Sludge, Foundry Sand, Ash. These materials are readily available and easy to handle. These materials could be used as an alternative to various stabilizers. It can be used in multiple fields like soil stabilization, concrete production, brick manufacturing, improving soil quality, and manufacturing of cement. On comparing it was concluded that these materials are economically, efficient and eco-friendly compared to traditional methods.
VARIOUS ARTIFICIAL INTELLIGENCE TECHNIQUES IN CONCRETE FOR DETERMINING CRACKING IN CONCRETE
Authors: Gour Prachi , Basant Kumar Dr.
Published: June 2024

Plastic shrinkage cracking is a common issue that can occur in concrete during the early stages of curing. It happens when the rate of evaporation from the surface of the concrete exceeds the rate at which moisture is being supplied to the concrete, resulting in a rapid loss of moisture and volume reduction. This, in turn, leads to the formation of cracks on the surface of the concrete. In the growing world of various technologies using the AI methods latest techniques are found for analyzing the cracking in concrete. Various parameters of cracking is determined by various techniques using the software tools and AI parameters. Researchers have found different methods. This study aims to create knowledge about few methods that are suggested to found the parameters of concrete cracking.
STABILIZATION OF BLACK COTTON SOIL BY USING CALCIUM CARBIDE RESIDUE AND BAGASSE ASH
Authors: Rajshekhar Gopal Rathod Dr. , Devgire Animesh Mahavir , Rakh Avinash
Published: June 2024

The development of road alignment over expansive clayey soil is becoming challenging in India. Smectite minerals are seen in black cotton soil. it exhibits strong swelling and shrinking characteristics. The construction of pavement structures on Black Cotton Soil is becoming irksome, because of its propensity to exhibit volume change behaviour and cause uplift pressure to light structures and pavement layers. In the process of stabilising the soil, its physical characteristics are changed for long-term tensile strength. Soil is stabilizing with addition of chemical additives. Calcium Carbide Residue (CCR) & Bagasse ash are two additives which are using for stabilization of Black cotton soil.
BLACK COTTON SOIL STABILIZATION BY USING BIO-ENZYME AND MARBLE DUST POWDER FOR PAVEMENT SUB-GRADE
Authors: Rajshekhar Gopal Rathod Dr. , Gayakawad Aishwarya P , Sonawane Sagar
Published: June 2024

Black Cotton Soils (BCS) pose challenges due to their susceptibility to vertical ground movements, particularly affecting Geotechnical Structures and Pavement. These issues are exacerbated in areas with poor subgrade soil, where pavement construction becomes prohibitively expensive. To address this, there's a growing shift towards exploring non-traditional, sustainable, and cost-effective alternatives. Despite this need, research on the reaction mechanisms of non-traditional soil stabilization methods is limited. In this context, the study explores the use of Marble Dust (MD) as a soil stabilizer and Bio Enzyme (BE), a natural and non-toxic liquid enzyme that expedites soil stabilization during construction. The study's objectives include evaluating geotechnical parameters like compaction, Atterberg's limits, and unconfined compressive strength while varying the ratios of marble dust and bio enzyme. Additionally, it employs microstructural-driven analytical techniques to investigate the reaction mechanism behind this soil stabilization approach. The findings hold promise for mitigating reactive soil expansion and promoting sustainable solid waste management practices.
PLANNING OF MOBILITY AND PARKING SERVICES FOR MIT ADT UNIVERSITY CAMPUS, PUNE
Authors: Rajshekhar Gopal Rathod Dr. , S Sourabh Chougule , Patil Satish B.
Published: June 2024

This research study delves into the issues of traffic congestion and parking management within the campus of MIT ADT University in Pune, Maharashtra, India. With the growing population, the study focuses on investigating the causes of congestion and other challenges faced by the campus. To gather relevant data, three surveys were conducted as part of the research project. These surveys included a traffic volume survey, an origin-destination survey, and a parking survey. By collecting data on traffic patterns, parking utilization, and vehicle movement, valuable insights were obtained. This data formed the basis for identifying key issues, such as bottlenecks and inadequate intersection design contributing to traffic congestion, as well as parking difficulties near specific buildings due to limited spaces. The study proposes recommendations to address these concerns, encompassing measures to alleviate bottleneck congestion, implement traffic channelizing techniques, consider lane expansion, improve parking design and management, enhance signage and wayfinding systems, and promote sustainable transportation practices. Regular surveys are suggested to monitor the effectiveness of the implemented solutions. By implementing these recommendations, campus authorities can improve traffic management, reduce congestion, and enhance parking facilities, thus improving the overall campus environment.
A CASE STUDY ON MAN-MADE HAZARDS IN THE INDIAN CONTEXT: ENVIRONMENTAL IMPACT AND THEIR MITIGATION MEASURES
Authors: Kumar Ashwini , Pawar Yash , Rastogi Om , K. K. Gupta Dr. , Garg Nikhil
Published: June 2024

This paper examines the environmental consequences of man-made hazards in India and proposes strategies to mitigate their effects and prevent future disasters. While the country is no stranger to natural calamities, man-made incidents such as nuclear power plant accidents, industrial pollution, and environmental degradation due to deforestation have become increasingly prevalent. As per the WHO (World Health Organization) annual report of 2020, over seven million people die annually from air pollution caused by hazardous chemicals, while another one million perish due to waterborne diseases, primarily in developing countries with high population density. Global warming fueled by excessive fossil fuel consumption and deforestation, contributes to climate change and weather-related disasters such as droughts and floods. To address this issue the paper advocates for a reduction in fossil fuel dependency and transmission to renewable energy sources such as solar and wind power. The paper also highlights how we can mitigate the effect of such hazards and what measures must be taken to avoid this kind of disaster. The paper highlights the benefit of large-scale afforestation efforts, particularly in tropical rain forests, to increase Earth’s green cover and counteract the rise in atmospheric carbon dioxide concentrations. By implementing these mitigation measures, India can move towards a more sustainable and environmentally resilient future.
CRYPTOCURRENCY: EVOLUTION AND FUTURE IMPACTS
Authors: Agarwal Ishaan , Singh Anshika
Published: June 2024

This article examines three key issues related to cryptocurrencies, with a primary focus on bitcoins, the most prominent cryptocurrency. The first issue addressed is the contention that cryptocurrencies lack qualifications to be classified as money due to the absence of legal tender recognition by the United States government. The study also evaluates the procedural frameworks employed by the Federal Reserve and the central bank of Sweden to assess the feasibility of introducing a digital currency. Additionally, the article explores the feasibility of blockchain technology as an independent and prosperous innovation, originally introduced in the bitcoin framework. The subject matter centers on digital currencies, particularly prominent examples like Bitcoin, Ethereum, and Ripple, known for their decentralized nature and blockchain technology. The study also explores blockchain wallets as digital repositories for managing various cryptocurrencies, using cryptographic techniques to secure and verify transactions while controlling new unit creation. Overall, the research aims to provide comprehensive insights into the world of digital currencies and blockchain technology.
DIAGNOSIS AND DETECTION OF VARIOUS DISEASES USING MACHINE LEARNING HEURISTICS: A STUDY
Authors: Nath Ira , Rakshit Pranati , Singh Dharmpal
Published: June 2024

Think about the circumstances of those residing in an area remote from a hospital. Consider the people who lack the resources to cover the hospital bills as well. There are some incredibly busy people in our society who do not have enough time in their lives to visit the hospital for the diagnosis of their own diseases or the diseases of other family members. In the aforementioned scenarios, diseases can be identified using cutting-edge medical technology, perhaps saving our precious lives. Several artificially intelligent diagnosis heuristics have been developed by researchers to differentiate between a number of common ailments. The focus of the chapter is on recent advances in machine learning (ML) that have had a significant impact on the diagnosis and recognition of various illnesses.
MARKER ASSISTED SELECTION AND ITS FUTURE USE
Authors: Laskar Dr. Saharuz Zaman , Ghosh Dr. Ajoy
Published: June 2024

Marker assisted selection (MAS) is a method used to select the dominant population of the product. MAS depends on the identification of the relationship between genetic markers and linked quantitative trait loci (QTLs). The relationship between markers and QTLs depends on the distance between the marker and the target feature. Once pointers linked to QTLs are defined, they can be used in selection programs. This method of using pointers in selection is called pointer assisted selection.MAS is useful when quality measurement is difficult and expensive, and features and characteristics are poor. MAS can help increase genetic diversity in breeders and can be used
BIOMEDICAL APPLICATIONS OF BIOMARKERS IN CURRENT TRENDS & FUTURISTIC PERSPECTIVES
Authors: Durga Dr. B. , Anandhi Dr. D.
Published: June 2024

Biomarkers are markers of normal biological functions, pathological activities, or drug-related pharmacological reactions. The last ten years have seen a significant growth in the implementation of biomarkers as potential indicators in the assessment of disease risk.The discovery and implementation of medical therapies depends on biomarkers, yet there is still a great deal of misunderstanding about the basic terms and ideas that underpin the use of biomarkers in clinical practice and research, especially in the areas of chronic illness and nutrition. Significant advantages might arise from defining various biomarkers more precisely and knowing when and how to use them. The applications of various biomarkers in medical diagnosis, pharmacodynamic/ response, anticipatory, protective, and susceptibility/risk aspects. With the advancement of personal health care and customized therapy, the research of biomarkers has promptly changed in the context of individual applications in clinical research, therapeutic development, and patient care, the recognition and verification of biomarkers is crucial for the development and discovery of drugs as well as for the detection, management, prediction, and combating disease. The consequences of recent developments in biomarkers advancement, such as electronic biomarkers made from mobile and sensor innovations, and complicated composites biomarkers. The need to guarantee the integrity and consistency of the science underneath a biomarker expansion, the advantages and disadvantages of biomarker-driven anticipatory toxicity and processes pharmaceuticals, and the significance of promoting cooperation throughout the whole wellness drug creation the environment. Although biomarkers are essential to the logical advancement of medical treatments and diagnostics, based on research biomarker invention that maintains up with scientists and medical demands can be achieved by prioritizing the superiority and accuracy of the scientific foundations and incorporating mutually beneficial science for regulation that involve different fields in the biomarker identification process of creation.. The use of biomarkers and their discovery in clinical and healthcare environments possess had an important effect on mankind.
FUNDAMENTALS, ROLES & REGULATORY REQUIREMENTS OF BIOASSAYS IN CURRENT PHARMACEUTICAL INDUSTRIES
Authors: Rawat Gandharv Singh , Mohabe Dr. Satish
Published: June 2024

The physicochemical and structural characteristics of proteins utilized as active pharmaceutical ingredients in biopharmaceuticals are critical factors in determining their biological activity. Consequently, the tests designed to assess the functionality of biopharmaceuticals serve as substantiating proof that these substances possess the necessary physicochemical attributes and structural conformation. The validation of the methodologies employed to examine the critical quality attributes of biopharmaceuticals stands as a crucial prerequisite for production within Good Manufacturing Practice (GMP) settings
CELL FUSION: UNITING CELLS FOR DISCOVERY AND THERAPEUTIC APPLICATIONS
Authors: Sajeev Advika , K S Bhoomika , Sarkar Pragati , K Soumya
Published: June 2024

Cell fusion, a fundamental biological process, encompasses diverse mechanisms such as membrane fusion leading to syncytium formation. Syncytia play pivotal roles across various biological processes, aiding in cell-cell communication and nutrient exchange. Notably, syncytium formation contributes significantly to physiological development, particularly in placental development by facilitating nutrient transfer and hormone production. In skeletal muscle formation, cell fusion is instrumental in embryonic development and postnatal differentiation, shaping the structure and function of muscles. Moreover, it serves as a mechanism for cellular reprogramming, evident in somatic cell nuclear transfer (SCNT) and induced pluripotent stem cells (iPSCs), holding promise for regenerative medicine and disease treatments. The applications of cell fusion in therapeutic avenues are extensive. Its relevance spans cell-based therapies, cancer research, tissue engineering, and organ transplants. Leveraging cell fusion holds potential for innovative treatments, offering avenues for disease management and regenerative interventions. This chapter provides a concise glimpse into the multifaceted roles of cell fusion, underscoring its significance in physiological processes, developmental biology, and its promising applications in therapeutic interventions across various fields.