bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementasi Perjanjian Perkawinan Sebelum, Saat Dan Sesudah Perkawinan
Authors: Masri Esther , Wahyuni Sri
Published: January 2021

Marriage agreement is an agreement made by the parties before and during the marriage which includes everything that is not limited to property but can also include other things outside of property. Since the decision of the constitutional court number 69/PUU-XIII/2015 the meaning of the marriage agreement has been loosened so that the marriage agreement can not only be made before, when the marriage is carried out but can be made as long as it is in the marriage bond as long as it does not violate the applicable legal rules, religious rules and norms decency. In the marriage agreement, the two parties namely the husband and wife can declare their will and agree on assets and separate assets. In this study the authors used a normative legal approach, namely a study using a statutory approach and descriptive analytical research characteristics. It can be concluded, based on the decision of the constitutional court number 69/PUU-XIII/2015, a marriage agreement can not only be made before, when a marriage is held, but can be made after a marriage is carried out to protect the constitutional rights of citizens and human rights.

 

Keywords: Marriage, Marriage Agreement, Property

 

Abstrak

 

Perjanjian perkawinan adalah perjanjian yang dibuat oleh para pihak sebelum dan saat dilangsungkan perkawinan yang mencakup segala sesuatu yang tidak terbatas pada harta benda tetapi juga dapat mencakup hal lain di luar harta benda. Sejak adanya Putusan Mahkamah Konstitusi nomor 69/PUU-XIII/2015 makna perjanjian perkawinan semakin dilonggarkan sehingga perjanjian perkawinan tidak hanya dapat dibuat sebelum, saat dilangsungkan perkawinan namun dapat dibuat sepanjang dalam ikatan perkawinan, asalkan tidak melanggar aturan hukum yang berlaku, aturan agama dan norma kesusilaan. Dalam perjanjian kawin, kedua pihak yakni suami istri dapat menyatakan kehendak dan bersepakat terhadap harta kekayaan untuk melakukan penyatuan harta, dan pemisahan harta. Dalam penelitian ini, penulis menggunakan pendekatan hukum normatif yaitu suatu penelitian dengan menggunakan pendekatan perundang-undangan dan sifat penelitian deskriptif analitis. Dapat disimpulkan, berdasarkan Putusan Mahkamah Konstitusi nomor 69/PUU-XIII/2015, perjanjian perkawinan tidak hanya dapat dibuat sebelum, saat dilangsungkan perkawinan namun dapat dibuat setelah dilaksanakan suatu perkawinan untuk menjaga hak-hak konstitusional warga negara dan hak asasi manusia.

 

Kata kunci: Perkawinan, Perjanjian Perkawinan, Harta Benda
Postoperative 30-day emergency department utilization after 7294 cranial neurosurgery procedures at a tertiary neuroscience center
Authors: Hardesty Douglas A. , Mooney Michael A. , Hendricks Benjamin K. , Catapano Joshua S. , Brigeman Scott T. , Bohl Michael A. , Sheehy John P. , Little Andrew S.
Published: January 2021

OBJECTIVE

Hospital readmission and the reduction thereof has become a major quality improvement initiative in organized medicine and neurosurgery. However, little research has been performed on why neurosurgical patients utilize hospital emergency rooms (ERs) with or without subsequent admission in the postoperative setting.

METHODS

This study was a retrospective, single-center review of data for all surgical cranial procedures performed from July 2013 to July 2016 in patients who survived to discharge. The study was approved by the institutional review board of the participating medical center.

RESULTS

The authors identified 7294 cranial procedures performed during 6596 hospital encounters in 5385 patients. The rate of postoperative ER utilization within 30 days after surgical hospitalization across all procedure types was 13.1 per 100 surgeries performed. The two most common chief complaints were pain (30.7%) and medical complication (18.2%). After identification of relevant surgical and patient factors with univariable analysis, a multivariable backward elimination logistic regression model was constructed in which Ommaya reservoir placement (OR 2.65, p = 0.0008) and cranial CSF shunt placement (OR 1.40, p = 0.0001) were associated with increased ER utilization. Deep brain stimulation electrode placement (OR 0.488, p = 0.0004), increasing hospital length of stay (OR 0.935, p < 0.0001), and increasing patient age (OR 0.988, p < 0.0001) were associated with lower rates of postoperative ER utilization. One-half (50%) of ER visit patients were readmitted to the hospital. New/worsening neurological deficit chief complaint (OR 1.99, p = 0.0088), fever chief complaint (OR 2.41, p = 0.0205), altered mentation chief complaint (OR 2.71, p = 0.0002), patient chronic kidney disease (OR 3.31, p = 0.0037), brain biopsy procedure type (OR 3.50, p = 0.0398), and wound infection chief complaint (OR 31.4, p = 0.0008) were associated with increased rates of readmission to the hospital from the ER in multivariable analysis.

CONCLUSIONS

The authors report the rates of and reasons for ER utilization in a large cohort of postoperative cranial neurosurgical patients. Factors identified were associated with both increased and decreased use of the ER after cranial surgery, as well as variables associated with readmission to the hospital after postoperative ER visitation. These findings may direct future quality improvement via prospective implementation of care pathways for high-risk procedures.
Cerebral arteriopathy in ACTA2 mutations: a spectrum of disease highlighted by a case of variable penetrance in two siblings
Authors: Tschoe Christine , Kim Teddy E. , Fargen Kyle M. , Wolfe Stacey Q.
Published: January 2021

Until recently, cerebral arteriopathy due to heterozygous mutations of the ACTA2 gene was considered a variant of moyamoya disease. However, radiographic analysis of patients with these mutations reveals a distinctive angiographic appearance from that seen in moyamoya disease. Several heterozygous missense ACTA2 mutations have been implicated in the development of this distinct cerebrovascular entity; however, the penetrance and systemic manifestations of these mutations vary based on the location of the amino acid replacement within the α–smooth muscle actin protein. The severity of the phenotype may also differ among patients within a single mutation type. There is limited literature on the safety and efficacy of revascularization procedures for ACTA2 arteriopathy, which have been limited to those patients with known Arg179His mutations. The authors provide a review of the breadth of mutations within the ACTA2 literature and report a case of two siblings with de novo ACTA2 Arg258Cys mutations with differing clinical courses, highlighting the utility of indirect revascularization with 8-year follow-up data. This case highlights the importance of early recognition of the angiographic appearance of ACTA2 cerebral arteriopathy and performance of genetic testing, as the location of the mutation impacts clinical presentation and outcomes.
An unusual case of a persistent, infected retroperitoneal fluid collection 5 years after anterior lumbar fusion surgery: illustrative case
Authors: Neal Matthew T. , Curley Kara L. , Richards Alexandra E. , Kalani Maziyar A. , Lyons Mark K. , Davila Victor J.
Published: January 2021

BACKGROUND

Anterior lumbar fusion procedures have many benefits and continue to grow in popularity. The technique has many potential approach- and procedure-related complications. Symptomatic retroperitoneal fluid collections are uncommon but potentially serious complications after anterior lumbar procedures. Collection types include hematomas, urinomas, chyloperitoneum, cerebrospinal fluid collections, and deep infections.

OBSERVATIONS

The authors present an unusual case of a patient with persistent symptoms related to a retroperitoneal collection over a 5-year period following anterior lumbar fusion surgery. To the authors’ knowledge, no similar case with such extensive symptom duration has been described. The patient had an infected encapsulated fluid collection. The collection was presumed to be a postoperative lymphocele that was secondarily infected after serial percutaneous drainage procedures.

LESSONS

When retroperitoneal collections occur after anterior retroperitoneal approaches, clinical clues, such as timing of symptoms, hypotension, acute anemia, urinary tract infection, hydronephrosis, elevated serum creatinine and blood urea nitrogen, low-pressure headaches, anorexia, or systemic signs of infection, can help narrow the differential. Retroperitoneal collections may continue to be symptomatic many years after anterior lumbar surgery. The collections may become infected after serial percutaneous drainage or prolonged continuous drainage. Encapsulated, infected fluid collections typically require surgical debridement of the capsule and its contents.
Surgical management of an extensive spinal epidural abscess: illustrative cases
Authors: Eroshkin Aleksey , Romanukha Dmytro , Voitsekhovskyi Serhiy
Published: January 2021

BACKGROUND

Extensive spinal epidural abscesses (SEAs) occupying three or more spinal regions are rare. This study aimed to address the key dilemma of surgical treatment for holospinal epidural abscesses, i.e., to determine the required scope of surgery and minimize surgical trauma with adequate purulent drainage.

OBSERVATIONS

Two patients with extensive SEAs were treated at the Neurosurgery Department of the Central Hospital of Ministry of Internal Affairs of Ukraine from 2018 to 2020. Both patients had a neurological deficit and general inflammatory response syndrome. Spinal magnetic resonance examinations were performed, showing that the first and second patients had extensive SEAs at T11/S1 and C2/L1, respectively. Both underwent minimally invasive abscess drainage via intra- and translaminar access at the most caudal point using an epidural silicone catheter in the cranial direction along the entire length of the abscess.

LESSONS

To achieve the key goal of extensive SEA treatment, i.e., to prevent the development of a persistent neurological deficit, immediate effective spinal canal decompression should be performed. Access method and scope should meet the requirements of spinal canal decompression and purulent content aspiration to the greatest possible extent while inducing minimal trauma.
[68Ga]-DOTATATE PET/CT and PET/MRI in the diagnosis and management of esthesioneuroblastoma: illustrative cases
Authors: Roytman Michelle , Tassler Andrew B. , Kacker Ashutosh , Schwartz Theodore H. , Dobri Georgiana A. , Strauss Sara B. , Capalbo Alyssa M. , Magge Rajiv S. , Barbaro Marissa , Lin Eaton , Osborne Joseph R. , Jana Ivanidze
Published: January 2021

BACKGROUND

Esthesioneuroblastoma (ENB), also known as olfactory neuroblastoma, is a rare sinonasal neuroectodermal malignancy with a slow onset of symptoms, favorable 5-year survival, and a propensity for delayed locoregional recurrence. Current treatment options include resection, adjuvant radiotherapy, and/or chemotherapy; however, because of its rarity and location, determining the optimal treatment for ENB has been challenging.

OBSERVATIONS

ENBs strongly express somatostatin receptors (SSTRs), particularly SSTR2, providing a molecular target for imaging and therapy.

LESSONs

The authors present a case series of ENBs imaged with [68Ga]-DOTATATE PET/MRI and PET/CT and discuss the emerging role of [68Ga]-DOTATATE PET for ENB diagnosis, staging, and treatment response monitoring.
Endovascular treatment of a ruptured posterior fossa pure arterial malformation: illustrative case
Authors: Chua Melissa M. J. , Gupta Saksham , Essayed Walid Ibn , Donnelly Dustin J. , Ziayee Habibullah , Vicenty-Padilla Juan , Das Alvin S. , Lai Rosalind P. M. , Izzy Saef , Aziz-Sultan Mohammad Ali
Published: January 2021

BACKGROUND

Pure arterial malformations (PAMs) are rare vascular anomalies that are commonly mistaken for other vascular malformations. Because of their purported benign natural history, PAMs are often conservatively managed. The authors report the case of a ruptured PAM leading to subarachnoid hemorrhage (SAH) with intraventricular extension that was treated endovascularly.

OBSERVATIONS

A 38-year-old man presented with a 1-day history of headaches and nausea. A computed tomography scan demonstrated diffuse SAH with intraventricular extension, and angiography revealed a right posterior inferior cerebellar artery–associated PAM. The PAM was treated with endovascular Onyx embolization.

LESSONS

To the authors’ knowledge, only 2 other cases of SAH associated with PAM have been reported. In those 2 cases, surgical clipping was pursued for definitive treatment. Here, the authors report the first case of a ruptured PAM treated using an endovascular approach, showing its feasibility as a treatment option particularly in patients in whom open surgery is too high a risk.
Analisis Kualitatif Kandungan Fenolik dalam Fraksi Etil Asetat dan Fraksi Metanol dari Ekstrak Kulit Jagung (Zea mays L.)
Authors: Suputri Yuniarthi Dwi , Ananto Agus Dwi , Andayani Yayuk
Published: January 2021

ABSTRAKProduksi tanaman jagung yang semakin meningkat menyebabkan peningkatan limbah kulit jagung semakin tinggi. Kulit jagung dapat dimanfaatkan dalam bidang kesehatan dan berpotensi sebagai antioksidan. Kulit jagung mengandung senyawa fenolik dan flavonoid yang dapat bertindak sebagai antioksidan. Tujuan dari penelitian ini adalah untuk mengetahui kandungan senyawa pada fenolikfraksi etil asetat dan fraksi metanol kulit jagung. Ekstraksi kulit jagung dilakukan dengan metode maserasi menggunakan pelarut etanol 96%. Fraksinasi ekstrak etanol kulit jagung dilakukan dengan fraksinasi bertingkat menggunakan pelarut metanol dan etil asetat. Kedua fraksi yang diperoleh kemudian dianalisis secara kualitatif dengan metode Kromatografi Lapis Tipis. Fase diam yang digunakan adalah plat silica gel G60F254 dan fase gerak yang digunakan adalah kombinasi eluen kloroform: etil asetat: n-butanol: asam format (5:2:2:1). Hasil pemisahan ditandai dengan munculnya noda bercak saat diamati dengan sinar UV 254 nm dan 366 nm. Nilai Rf bercak yang muncul kemudian dihitung lalu dibandingkan dengan nilai Rf literatur untuk mengidentifikasikan senyawa yang terpisah. Hasil analisis kualitatif fraksi etil asetat dan fraksi metanol kulit jagung menunjukkan keberadaan senyawa fenolik. Hasil ini ditunjukkan dengan munculnya noda bercak dengan nilai Rf 0,75 yang memiliki kemiripan dengan nilai Rf asam galat (0,76). Kata kunci : Kulit jagung; Kromatografi lapis tipis; Analisis kualitatif. ABSTRACTCorn production keeps increasing causing increasing in corn husk waste. Cornhusk can be used in medical field and have potential as an antioxidant. Cornhusk contains phenol and flavonoid metabolites that can act as antioxidants. The aim of this study is to determine the presence of phenol metabolites in ethyl acetate and methanol fraction of cornhusk. Cornhusk extraction was carried out by a maceration method using ethanol 96%. Fractionation of ethanolic cornhusk extract was carried out by liquid-liquid extraction using a separating funnel with methanol and ethyl acetate solvent. The two fractions then analyzed qualitative by Thin Layer Chromatography. The stationary phase used is silica gel G60F254. The mobile phase used is a combination of chloroform: ethyl acetate: n-butanol: formic acid (5:2:2:1). The separation result marked by the presence of stains when observed by UV 254 nm and 366 nm light. The Rf value then measured and compared to Rf value in the literature to determine the separated substance. The qualitative analysis result of corn husk ethyl acetate fraction and methanol fraction indicated the presence of phenolic metabolites. This result is showed by the presence of stain with Rf value 0,75 that has similarity with Rf value of gallic acid (0,76). Keywords : Cornhusk; Thin layer chromatography; Qualitative analysis.
Kepatuhan Ibu Hamil Dalam Mengkonsumsi Tablet Fe (Ferrum) Terhadap Kejadian Anemia Di Desa Langgenharjo Kecamatan Juwana
Authors: Pratiwi Yulia , Safitri Tya
Published: January 2021

ABSTRAKSelama kehamilan, tubuh wanita memerlukan lebih banyak darah untuk mendukung pertumbuhan bayi. Wanita hamil berisiko tinggi mengalami anemia defisiensi besi. Wanita hamil membutuhkan zat besi tambahan untuk memasok oksigen ke bayi. Untuk itulah wanita hamil perlu mengkonsumsi Fe untuk mensuplai kebutuhan darah. Kepatuhan dalam konsumsi tablet Fe merupakan hal yang perlu diperhatikan. Tujuan penelitian ini adalah untuk mengetahui bagaimana pengaruh kepatuhan ibu hamil dalam konsumsi tablet Fe terhadap tingkat kejadian anemia di Desa Langgenharjo, Kecamatan Juwana. Penelitian ini menggunakan jenis rancangan observasional analitik dengan pendekatan cross sectional, observasi atau pengumpulan data, serta pemberian edukasi di Desa Langgenharjo. Metode yang digunakan dalam penelitian adalah metode kuantitatif yang bersifat deskriptif non eksperimental.  Instrumen penelitian yang digunakan dalam peneltian ini berupa kuesioner dan edukasi. Data dianalisis dengan SPSS 22,0 dengan menggunakan uji normalitas, uji Chi-Square. Hasil penelitian menunjukan bahwa tidak terdapat hubungan antara kepatuhan ibu hamil dalam mengkonsumsi tablet Fe terhadap tingkat kejadian anemia dengan p (value) 0,229.Kata kunci : Kepatuhan; Ibu hamil; Konsumsi; Tablet Fe.ABSTRACTDuring pregnancy, a woman's body needs more blood to support the baby's growth. Pregnant women are at high risk for iron deficiency anemia. Pregnant women need extra iron to supply oxygen to the baby. For communication, pregnant women need to take iron to supply blood. Compliance with the consumption of Fe tablets is something that needs attention. The purpose of this study was to see how compliance of pregnant women in consuming Fe tablets on the incidence of anemia in Langgenharjo Village, Juwana District. This research used an analytic observational design with a cross sectional approach, observation or data, as well as providing education in Langgenharjo Village. The method used in this research is quantitative quantitative which is descriptive non-experimental. The research instruments used in this research were questionnaires and education. Data were analyzed using SPSS 22.0 using normality test, Chi-Square test. The results showed that there was no effect between pregnant women in consuming Fe tablets on the incidence rate of anemia with p (value) 0.229.Keywords : Compliance; Pregnant women; Consumption; Fe Tablet.
Collaborative Teaching: Bringing Language Teaching to the English Content Classroom
Authors: Jabeen Sajda
Published: January 2021

ABSTRACT The present study looks at collaborative teaching and how it can be incorporated as a remedial technique in an English content course at the Masters level. Using action research as its method, and the view W. W. Murawski takes on co-teaching while appropriating it for a non-inclusive classroom, the research looks at how co-teachers’ use of this technique in a co-taught classroom can enhance their teaching experience and supplement the students’ understanding of the content. The current study uses the data in the form of reflections, by both the co-teachers, after each session, for analysis in light of their own earlier experiences. The findings show that taking up co-teaching in an English content course at Masters level can be used as a remedial teaching technique to improve the weak language skills of learners.
Faktor yang Berhubungan dengan Perilaku Pencegahan HIV/AIDS pada Kelompok LSL di Kota Palu
Authors: Septiani
Published: January 2021

LSL adalah singkatan yang menggambarkan Laki-laki berhubungan Seks dengan Laki-laki. LSL adalah salah satu kelompok berisiko tinggi penularan HIV/AIDS, karena perilaku seksual mereka adalah anal dan seks oral. Berdasarkan data dari Dinas Kesehatan Kota Palu pada tahun 2019 bahwa 94 kasus HIV terjadi pada LSL. Tujuan dari penelitian ini adalah untuk mengetahui faktor yang berhubungan dengan perilaku pencegahan HIV/AIDS pada kelompok LSL di Kota Palu. Jenis penelitian adalah kuantitatif dengan pendekatan cross sectional. Populasi berjumlah 284 orang, setelah menggunakan rumus slovin didapatkan sampel sebanyak 74 orang yang diambil melalui teknik snawball sampling. Analisis data menggunakan univariat dan bivariat menggunakan uji chi-square dengan nilai α<0,05. Hasil penelitian menunjukkan beberapa variabel yaitu: pengetahuan (p= 0,037), sikap (p= 0,005),  dan dukungan petugas kesehatan (p = 0,000) berhubungan dengan perilaku pencegahan HIV/AIDS pada kelompok LSL di Kota Palu. Kesimpulan: Ada hubungan antara pengetahuan, sikap, dukungan petugas kesehatan dengan perilaku pencegahan HIV/AIDS pada kelompok LSL di Kota Palu, disarankan kepada LSL untuk meningkatkan perilaku pencegahan dengan menggunakan kondom secara konsisten dan memanfaatkan layanan konseling dan tes HIV, dan petugas kesehatan dapat memberikan bantuan perawatan dan konseling tanpa stigma dan diskriminasi.
Role of the Kazakhstan-German Cooperation in Improving Scientific Tools for Evaluation of Vocational Education Programs
Authors: Karstina S. G. , Zechiel O. N. , Machado C.
Published: January 2021

The work carried out within the framework of the German-Kazakh project “GeKaVoс – Transfer of dual training in logistics, mechatronics and sustainable energy supply to Kazakhstan” can be considered as one of the crucial aspects of the contribution to improving the quality of system of technical and vocational education (TVET), the achievement of high rates of employment of graduates of the TVET system, improve the ratio of supply and demand in the labor market.

As the analysis of the TVET system in Kazakhstan presented in the article shows, different forms of cooperation between participants of the educational process in the country (corporate partnership, industrial clusters, patronage of large and medium-sized enterprises over educational institutions, etc.) contribute to the development of a market-oriented education system. Monitoring and evaluation of the effectiveness of technical and vocational education, as well as identifying opportunities to improve its quality and scope require understanding of its nature, its functions, goals and key characteristics, the application of effective scientific tools to assess vocational technical education and training of trainers (tutors) (TVET).

The paper shows that the success of the transfer of educational programs depends primarily on the willingness to work together of all the stakeholders, the creation of systematic structures of interaction in the development of educational programs of different levels, improving methods of forecasting demand not only for certain professions, but also for professional and pre-professional competencies. The purpose of scientific evaluation of the dual system and workplace training is to prove its effectiveness as an educational strategy that provides students with real work experience, where they can apply social and technical skills and develop them.
Online Courses: To Accept Impossible to Ignore
Authors: Lobova S. V. , Ponkina E. V.
Published: January 2021

Online courses are changing the landscape of higher education. However, their adoption by the teaching community of Russian universities has not yet been fully studied. The conducted sociological research made it possible to assess the involvement of Russian university lecturers in the processes of digitalization of education, to determine the motives for their activities in creating and integrating online courses into the educational process, and to form an understanding of the acceptance of online learning by the Russian teaching community. The pyramid of acceptance of Cox and Trotter’s open educational resources is a repulsive idea for the study. The empirical basis of the study was the responses and opinions of teachers of Russian universities, representing different categories of universities.

The results of the research can be of practical significance in determining the directions of social policy of education digitalization at the state level in terms of developing stimulating and motivating measures and measures to support and provide the necessary guarantees to lecturers, especially regional ones, during the transformation period.
New IGIP Curriculum for Advanced Training of Engineering University Teachers
Authors: Solovyev A. N. , Prikhodko V. M. , Petrova L. G. , Makarenko E. I.
Published: January 2021

The discussion of the new Curriculum for pedagogical training of teachers of technical disciplines, prior to its approval by the IGIP Executive Committee in the fall of 2019 is considered. The previous version of this Curriculum was approved in 2013. Over the past period, there have been significant changes in the use of ICT in training, discussed in the proposals of the National IGIP Offices, in the proceedings of the Annual IGIP Conferences, including the International Conference ICL-IGIP held in Tallinn on 23–25 September, 2020. At this Conference, IGIP President Hanno Hortsch in his presentation has published the IGIP curriculum in the form of a table (now we present it in translation into Russian) and reported about his vision of its use. The authors formulate their point of view on the topic basing on the overview of the presentations given at this Conference and relevant articles published in the latest issues of the journal “Higher education in Russia”.
Existence and asymptotic behavior of solutions for a class of semilinear subcritical elliptic systems
Authors: Arruda Suellen Cristina Q. , Figueiredo Giovany M. , Nascimento Rubia G.
Published: January 2021

In this paper we study the asymptotic behaviour of a family of elliptic systems, as far as the existence of solutions is concerned. We give a special attention to the asymptotic behaviour of W and V as ε goes to zero in the system [Formula: see text] where [Formula: see text], W and V are positive potentials of [Formula: see text] class and Q is a p-homogeneous function with subcritical growth. We establish the existence of a positive solution by considering two classes of potentials W and  V. Our arguments are based on penalization techniques, variational methods and the Moser iteration scheme.
Cognitive Effects of Aerobic Exercise in Alzheimer’s Disease: A Pilot Randomized Controlled Trial
Authors: Yu Fang , Vock David M. , Zhang Lin , Salisbury Dereck , Nelson Nathaniel W. , Chow Lisa S. , Smith Glenn , Barclay Terry R. , Dysken Maurice , Wyman Jean F.
Published: January 2021

Background: Aerobic exercise has shown inconsistent cognitive effects in older adults with Alzheimer’s disease (AD) dementia. Objective: To examine the immediate and longitudinal effects of 6-month cycling on cognition in older adults with AD dementia. Methods: This randomized controlled trial randomized 96 participants (64 to cycling and 32 to stretching for six months) and followed them for another six months. The intervention was supervised, moderate-intensity cycling for 20–50 minutes, 3 times a week for six months. The control was light-intensity stretching. Cognition was assessed at baseline, 3, 6, 9, and 12 months using the AD Assessment Scale-Cognition (ADAS-Cog). Discrete cognitive domains were measured using the AD Uniform Data Set battery. Results: The participants were 77.4±6.8 years old with 15.6±2.9 years of education, and 55% were male. The 6-month change in ADAS-Cog was 1.0±4.6 (cycling) and 0.1±4.1 (stretching), which were both significantly less than the natural 3.2±6.3-point increase observed naturally with disease progression. The 12-month change was 2.4±5.2 (cycling) and 2.2±5.7 (control). ADAS-Cog did not differ between groups at 6 (p = 0.386) and 12 months (p = 0.856). There were no differences in the 12-month rate of change in ADAS-Cog (0.192 versus 0.197, p = 0.967), memory (–0.012 versus –0.019, p = 0.373), executive function (–0.020 versus –0.012, p = 0.383), attention (–0.035 versus –0.033, p = 0.908), or language (–0.028 versus –0.026, p = 0.756). Conclusion: Exercise may reduce decline in global cognition in older adults with mild-to-moderate AD dementia. Aerobic exercise did not show superior cognitive effects to stretching in our pilot trial, possibly due to the lack of power.
Comparison of Long-term Ambulatory Function in Patients with Duchenne Muscular Dystrophy Treated with Eteplirsen and Matched Natural History Controls
Authors: Mendell Jerry R. , Khan Navid , Sha Nanshi , Eliopoulos Helen , McDonald Craig M. , Goemans Nathalie , Mercuri Eugenio , Lowes Linda P. , Alfano Lindsay N. ,   on behalf of the Eteplirsen Study Group
Published: January 2021

Background:

Duchenne muscular dystrophy (DMD) is a rare, X-linked, fatal, degenerative neuromuscular disease caused by DMD gene mutations. A relationship between exon skipping and dystrophin production in exon 51-amenable patients treated with eteplirsen (EXONDYS 51®) is established. Once-weekly eteplirsen significantly increased dystrophin, with slower decline in ambulatory function compared to baseline. Long-term treatment with eteplirsen leads to accumulation of dystrophin over time and observed functional benefits in patients with DMD.

Objective:

Compare long-term ambulatory function in eteplirsen-treated patients versus controls.

Methods:

Study 201/202 included 12 eteplirsen-treated patients assessed twice/year for ambulatory function over 4 years. Ambulatory evaluations (6-minute walk test [6MWT], loss of ambulation, and North Star Ambulatory Assessment [NSAA]) were compared with matched controls from Italian Telethon and Leuven registries.

Results:

At Years 3 and 4, eteplirsen-treated patients demonstrated markedly greater mean 6MWT than controls (difference in change from baseline of 132 m [95%CI (29, 235), p = 0.015] at Year 3 and 159 m [95%CI (66, 253), p = 0.002] at Year 4). At Year 4, a significantly greater proportion of eteplirsen-treated patients were still ambulant versus controls (10/12 vs 3/11; p = 0.020). At Year 3, eteplirsen-treated patients demonstrated milder NSAA decline versus controls (difference in change from baseline of 2.6, 95%CI [-6, 11]), however, the difference was not statistically significant; Year 4 control NSAA data were not available.

Conclusion:

In this retrospective matched control study, eteplirsen treatment resulted in attenuation of ambulatory decline over a 4-year observation period, supporting long-term benefit in patients with DMD.
Myocardial performance index in term appropriate and small for gestational age neonates - a cross sectional study
Authors: Vats K. , Choudhary S.K. , Kumar D. , Maria A. , Bandopadhyay T.
Published: January 2021

BACKGROUND:

It is known that small for gestational age (SGA) babies may be at an increased risk of cardiovascular diseases during adulthood. There is paucity of literature regarding comparative cardiac functions of SGA and appropriate for gestational age (AGA) babies in neonatal period. The present study was conceived to compare the cardiac function of term small and appropriate for gestational age (AGA) babies through a relatively novel echocardiographic index in early neonatal period.

OBJECTIVES:

To compare values of myocardial performance index (MPI) index (MPI = IVCT + IVRT/ET) at 48–72 hours of age among AGA and SGA babies.

METHODS:

Morphological and anthropometric assessment of serially born term babies was done at time of birth to recruit hundred each of AGA and SGA babies. Tissue Doppler Imaging (TDI) was done between 48–72 hours for each enrolled baby to assess both right and left ventricle MPI in each group.

RESULTS:

Mean±SD values for right ventricular MPI in AGA and SGA groups were 0.268 + 0.007 and 0.30 + 0.026 respectively ( p < 0.001). Mean±SD values for left ventricular MPI in AGA and SGA groups were 0.25 + 0.012 and 0.30 + 0.017 respectively ( p < 0.001). There was significant negative correlation between MPI values for either ventricles and the birth weight (spearmen’s rho of –0.66) ( p < 0.001). Mean±SD values for LVET in AGA and SGA group were 0.304 + 0.026 and 0.266 + 0.032 respectively ( p < 0.001).

CONCLUSION:

MPI had a higher absolute value in the SGA babies as compared to AGA babies. These observations point towards suboptimal cardiac performance among SGA babies as compared to AGA babies on the basis of myocardial performance index.
Nutrition as a socio-economic institution
Authors: Zhuravleva Lyudmila , Zarubina Elena , Ruchkin Aleksey
Published: January 2021

Abstract. Purpose. The article describes the economic component of routine eating behavior. Based on the ideas of the structural-functional paradigm and classical economic institutionalism, as well as the data of a sociological study conducted by the authors using the original methodology, the analysis of nutrition as a socio-economic institution that directly affects the distribution of resources and household costs is presented. Methods. To test the hypothesis of the formation of institutionally regulated food practices in modern society, the authors conducted a sociological study in September 2020. An integrative research strategy was applied using qualitative and quantitative methods of collecting social information, ensuring the quality and reliability of the data obtained. Implementing qualitative methods, we used narrative interviews, included observation, focus groups and written surveys (provoked by researchers essays on nutrition problems, presented by respondents in free form). The quantitative method was presented by a pilot smart survey (N = 75). Results. Conclusions: on the formation of a model of healthy nutrition in the majority of respondents and that nutrition increasingly acquires the features of a social institution and depends on the functioning of other social institutions in the economic, political, social and cultural spheres. First of all, the role of the state, the institution of property, education, culture, science is increasing, and their role in the formation of ecological healthy consumption of various population groups is increasing. Scientific novelty. Programs of social and economic support of vulnerable segments of the population, creation of conditions for an exit from “coronavirus crisis” are necessary. The problem of food security requires innovative programs for the development of the agro-industrial complex, modernization of logistics supply chains of food “from field to counter”, the creation of large wholesale distribution centers and investments in agricultural science.
Digital technologies as a factor of innovative development of information support for an agricultural dairy production enterprise management
Authors: KRASIL'NIKOVA L.
Published: January 2021

Abstract. The paper focuses on the special role of the use of digital devices and digital technologies in the development of information support for the management of dairy production within the framework of an integrated automated management system for agricultural enterprises in a market economy. Currently, in the Russian agro-industrial complex the use of modern digital technologies in the organization and functioning of network information support for making appropriate decisions is a strategically important innovative factor in improving the efficiency of management of an agricultural enterprise, including the processing of raw cow's milk and the production of planned assortment of dairy products. The purpose of this paper is to clarify the theoretical foundations and provisions that allow identifying and classifying the unique properties of digital technologies, the use of which can significantly improve the efficiency of management of agricultural enterprises of the agro-industrial complex, as well as to develop an organizational and economic model of automated network formation of information support for the management of dairy production. Methods. The methodological basis of this article consists of system, complex, situational and computer approaches, methods of comparative economic analysis, economic and mathematical modeling, network interaction and principles of functioning of information management support. Results. As a result of the study, author suggests a conceptual approach to the use of digital technologies as the factor of innovative development information support of agricultural enterprise management in the agro-industrial complex for the production of dairy products based on the identified characteristic properties of digital technologies (manufacturability, functionality, flexibility, integrability, informativeness and minimality) that can generate, store, and instantly provide the necessary information for decision-making. Scientific novelty. During the study, the results obtained which are of scientific novelty in the application of digital technologies for the development of management information production of dairy products, in particular, the author defined the concept "digital technology" and developed the organizational-economic model of automatic network formation of information support for management of the production of dairy products, covering the network of specialists workplaces in the basic and supportive production and maintenance processes at an agricultural enterprise.
Technical service in agro-industrial complex as a factor of sustainable development of the agrarian economy
Authors: Kruzhkova Tat'yana , Ruschickaya Ol'ga , Stozhko Konstantin , Stozhko Dmitriy
Published: January 2021

Abstract. In conditions of macroeconomic instability and growing risks, the role of technical service in the work of agricultural enterprises is significantly increasing. There are qualitative changes in the functioning of technical services due to the transition to a new technological structure and the modern digital economy. The role and importance of technical and technological services is increasing at the present stage in connection with the transition from lean production - to the model of “fast-reacting production”. The article notes that the deterioration of the quality of the ecological environment, accelerated depreciation of fixed assets, the wear of which reaches 70 % or more, have a negative impact on the development of the agro-industrial complex (AIC). The solution to these problems is based on the modernization of industries and the intensification of agricultural production, which is characterized by additional investment of labor and funds per unit of land area. In this area, a number of important problems related to the reorganization of maintenance, its financing, informatization, digitalization, etc., have become aggravated in recent years. The efficiency of the functioning of the agro-industrial complex largely depends on the solution of these problems at the present stage. The purpose of the study is to analyze and assess the current state of the field of technical and technological services for agricultural enterprises and the prospects for its further development. The most important condition for improving this block of the reproduction process in the agro-industrial complex is the increase in state funding and its effective targeted distribution in specific areas of innovative development. The results of the study are to identify the lack of inclusion of maintenance in the plans for innovation activities of agricultural enterprises, in connection with which recommendations are proposed to remedy the situation (creation of own technical and technological maps for the development of agricultural enterprises and the intellectualization of its material and technical services). Methods used: analysis and synthesis, comparison and observation. The scientific novelty is the analysis of indicative financial planning and a flexible system of targeted budgeting of production assignments for servicing agricultural enterprises.
Evolución Reciente del Endeudamiento Externo de los Bancos Colombianos - Diciembre de 2020
Authors:   Departamento de Estabilidad Financiera
Published: January 2021

El objetivo de este informe es describir la evolución reciente de las líneas de crédito en moneda extranjera de los bancos colombianos y presentar los principales resultados de la última encuesta de endeudamiento externo y cupos, la cual fue aplicada por el Departamento de Estabilidad Financiera del Banco de la República a una muestra representativa de bancos comerciales que tienen líneas de crédito en moneda extranjera.
BERDERMA SEBAGAI LANGKAH SOLUSI EKONOMI DI BABAKAN TANGERANG SELATAN
Authors: . Liawati , Zulkarnain Iskandar , . Nariah , . Karolina , Hanum Nurilah
Published: January 2021

Pada pelaksanaan Pengabdian Kepada Masyarakat kali ini, kami melakukan kerjasama dengan Kelurahan Babakan Tangerang Selatan di daerah babakan kelapa dua. Saat ini pemerintah pusat sudah mengeluarkan peraturan warga dilarang keluar rumah disebabkan adanya pandemic covid-19. Peraturan dikeluarkan guna mencegah penyebaran covid-19 disekitarnya, atau wilayah Tangerang Selatan sehingga dikeluarkan peraturan resmi daerah mengenai Pembatasan Sosial Bersekala Besar ( PSBB ). Belakangan ini banyak masyarakat yang terkena efek dari wabah covid-19 sehingga banyak yang mengalami kesulitan secara ekonomi. Ada sebagian masyarakat khususnya menengah kebawah bener-benar kehilangan pekerjaan akibat efek akibat wabah yang berkepanjangan. Dari problema kita tersebut maka tergerak hati kami untuk membantu para korban yang sulit memenuhi kebutuhannya sehari- hari maka sebagai solusi dalam mengatasi ekonomi tersebut maka pentingnya berdema terhadap bersama. Tentunya berderma adalah sebagai langkah solusi ekonomi yang sangat efektif untuk menghadapi krisis wabah ini. Jenis berdema yang dilakukan dapat berupa materil maupun inmateriil, langkah inmateriil seperti memberikan sedekah ilmu dan bergotong royong kemudian langkah materiil seperti memberikan sembako dan uang secukupnya kepada para duafa sehingga mereka dapat bertahan hidup. Dengan berderma maka dapat menumbuhkan jiwa social dan juga meningkatkan kualitas kemanusiaan. Selain itu memperkuat hubungan baik kita tehadap allah sebagai pencipta makhluk.
PERENCANAAN WAKTU DAN PERENCANAAN KEUANGAN IBU-IBU PKK DI KELURAHAN REMPOA, KECAMATAN CIPUTAT TIMUR, KOTA TANGERANG SELATAN
Authors: Qurbani Derita , Priyanto Aria Aji , Abidin Ali Zaenal , Sulistiani Sinta , Prasetyo Hendri
Published: January 2021

Waktu merupakan hal yang sangat penting, keberhasilan dalam kehidupan ditentukan oleh seberapa efektif kita dalam memanfaatkan waktu,Bagaiman waktu dibuat untuk mencapai tujuan tujuan yang ditentukan serta langka apa saja yang harus diperhatikan dalam pengelolaan waktu. Dalam perencanaan keuangan, bahwa bagaimana kita bisa memanfaatkan sumber daya yang ada untuk memenuhi kebutuhan dan bahkan beberapa ada yang bertujuan untuk mendapatkan keunytungan. Perencanaan keuangan diperlukan untuk persiapan agar kehidupan lebh sejahtera di masa depan. Adapun tujuan dari Pengabdian kepada Masyarakat (PKM) ini adalah untuk berbagi pengetahuan tentang bagaimana mengaplikasikan perencanaan waktu dan perencanaan keuangan pada Ibu-ibu PKK di Kelurahan Rempoa, Kecamatan Ciputat Timur, Kota Tangerang Selatan. Dalam melaksanakan kegiatan PKM digunakan beberapa meode pelatihan, yaitu: 1) Metode Ceramah/Presentasi. Metode ceramah/presentasi dipilih untuk memberikan penjelasan tentang: a. Pengertian waktu dan pentingnya perencanaan waktu. b. Presentasi mengenai materi pengertian keuangan dan perencanaan keuangan; 2) Metode Tanya Jawab. Metode tanya jawab sangat penting bagi para peserta pelatihan. Metode ini memungkinkan ibu PKK menggali pengetahuan sebanyak-banyaknya tentang perencanaan waktu dan perencanaan keuangan; 3) Sharing Session Tentang mengoptimalkan pengelolaan waktu dan keuangan. Sharing session ini diberikan kepada para peserta pelatihan dalam memberikan masukan dan bimbingan untuk mempraktekan materi yang diperoleh. Harapannya, peserta pelatihan dapat menguasai materi pelatihan yang diterima dan dapat diaplikasikan dalam kehidupan sehari - hari. Adapun hasil dari kegiatan Pengabdian kepada Masyarakat ini adalah perencanaan waktu dan perencanaan keuangan bagi rumah tangga ibu ibu PKK bagaimana memanfaat kan waktu sebaik baiknya dan merencanakan keuangan sesuai dengan kondisi kehidupannya untuk menghindari pemborosan dalam menigkatkan kualitas kehidupannya.Merencanakan waktu untuk mencapai tujuan kegiatan kegiatan yang menghasilkan serta merencanakan keuangan dengan proses yang berkesinambungan dan bersifat dinamis. Pada suatu saat, rencana tersebut dapat memerlukan penyesuaian
ANALISIS ATAS PENAFSIRAN FAKHR AL-DIN AL-RAZI TENTANG AL-HURUF AL-MUQATTA’AH
Authors: Ilyas Ilham Ilyas
Published: January 2021

This article discusses about al-huruf al-muqatta’ah in the book Mafatih al-Gaib by Fakhr al-Din al-Razi. Which contains discussion, the first discussion: how is Fakhr al-Din al-Razi’s interpretation about al-huruf al-muqatta’ah ? the second discussion: what is Fakhr al-Din al-Razi’s comment on the interpretation of scholars about al-huruf al-muqatta’ah ? this research is a qualitative tafsir study based on the study of the kitab. The propose of the study is that the data is taken from the kitab related to the research title. The approach used is tafsir science approach, language and philosophy. Researchers make al-huruf al-muqatta’ah as an object of research by using several books related to it to find out the interpretation of scholars (especially Fakhr al-Din al-Razi) about al-huruf al-muqatta’ah. The reason why the researcher choose this title its because there are differences in opinions of scholars into two opinions. First opinion: these letters are the secret of Allah, second opinion: the purpose of al-huruf al-muqatta’ah can be known and there are many words of scholars about itu, even though there was no direct axplanation from the Prophet Muhammad about the meaning of al-huruf al-muqatta’ah. Therefore researchers think it is necessary to conduct research. The result of this study founds that Fakhr al-Din al-Razi strengthened the opinion that al-huruf al-muqatta’ah is the name of surah and to attract the attention of non muslims to read the Qur’an after they advised one another to turn away from the Qur’an.
KISAH NABI NUH DALAM AL-QUR’AN (Pendekatan Intertekstual Julia Kristeva)
Authors: Khikmatiar Azkiya
Published: January 2021

This article discusses the story of Noah in the Qur'an. As a story contained in the Qur'an and the Bible, the story of Noah is very important to find the the differences between them. Therefore, the used approach  is intertextuality initiated by Julia Kristeva who tried to compare two narrations. By using this approach , we found many differences. In the structure of narration, al-Qur’an does many simplifications, so that the haplological principle becomes dominant in each fragment. However, in other fragments other principles are also found such as existence, modification, and conversion. The most basic difference between them is in theme of the story. The story of Noah in the Qur'an has monotheism or tauhid theme, while in the Bible the theme is human crime.
Preventive Maintenance Scheduling on Belt Conveyor Using Failure Mode Effect and Criticality Analysis
Authors: Kristian Fernado Putra , Mulyono Julius , Santosa Hadi
Published: January 2021

PT. X is a services and manufacturing company. PT. Y is one of some of industrial companies use the services of PT. X, is one of the biggest chemical fertilizer producer in Southeast Asia. PT Y uses 66 belt-conveyors for distributing the material. In order to arrange maintenance schedule, used preventive maintenance calculations using Failure Mode Effect and Critically Analysis method (FMECA). Preventive maintenance is used to schedule the maintenance of the conveyor belt’s components (belt and primary cleaner). Data analysis obtained a critical belt values are 2.521𝑥10−3 and 1.863𝑥10−3, respectively, on the primary cleaner component. Furthermore, effective maintenance and evaluation time intervals which obtained for belt components is indicating operation time with 92% reliability level or about 215 hours.