bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementation of the competence idea into the primary education in Ukraine – the reflective analysis based on the European Union benchmarks
Authors: Savchenko Oleksandra , Lokshyna Olena
Published: March 2020

The generation of the competence education idea in Ukraine based on the EU benchmarks is studied. It is underlined that the transformation of the national education into the competence base is a component of the European integration of Ukraine. The authors made conclusion that the Ukrainian education has gone from proclaiming the idea of the competence education, its conceptual justification to implementation. The research results evidence that the support of the competence idea at the level of educational policy is the most successful in Ukraine. At the same time, at the implementation level the competence idea meets a number of challenges due to the novelty of a clear correlation between strategic, didactic and methodological levels. The authors conclude that the problem of the formation of key competences, firstly of transversal or cross-curricular ones, remains underdeveloped; the aspects of crosscurricular links and integration of the education content requires further development; the level of assessing younger students in competencies is even more underdeveloped. On the other hand, the authors generalise that common globalization challenges, powerful integration processes in Europe, Europeanization affecting the European countries outside the EU borders contribute greatly to the synchronization of the education in Ukraine with EU standards.
Analysis of the state of formation of future teacher’s communicative competence as a condition of providing the quality of general secondary education
Authors: Trubavina Iryna , Vasylieva Svitlana , Martyniuk Anna
Published: March 2020

The scientific novelty of the article is that the authors have revealed the average level of the state of formation of communicative competence (CC) of the third-year students. The cognitive and emotional components dominate among all CC components (it can be observed among students of the Faculty of Natural Sciences, Faculty of Arts). The behavioral component of the CC is better formed among students of the Faculty of Foreign Philology and the Faculty of Arts and Graphics. The communicative tolerance prevails among students of the Faculty of Physical Education as well as the Faculty of Arts and Graphics. Moreover, the two factors influencing CC were revealed: the external factors (organization of students’ subject leisure; professional-oriented educational work with students; content of education at institutions of higher pedagogical education: specialty of the chosen profession, increased cycle of humanities and psychological and pedagogical disciplines, active pedagogical practice of students; age of students to work with, different categories of children and adults to communicate with, pedagogical skills and CC of teachers); the internal factors (students’ attitude towards self-development, self-education, students’ life and social experience, motivation for acquiring a specialty and CC, humanistic orientation of future teacher’s personality, persona’s orientation to “person to person” profession)
Narrative tolerance: on the road to unbiased history, cultural tolerance and civil society
Authors: Mishalova Olena
Published: March 2020

The article examines a concept of narrative tolerance as the basic structure of cultural tolerance and modern civil society. It is proposed to consider narrative tolerance as an effective methodological tool to create a tolerant inclusive sociocultural world paradigm. The tolerant sociocultural approach in history studying and teaching is a crucially important condition that makes it possible to resolve protracted historical conflicts both within and beyond countries and, as a result, leads to reconciliation and mutual forgiveness.
The relationship between education, income, economic freedom and happiness
Authors: Stryzhak Olena
Published: March 2020

Education is a factor for economic prosperity and social development in modern society. As well education allows its owner to receive a higher income and gives the opportunity for self-expression, creative fulfilment, as well as moral satisfaction from current activities. The life of educated people is not only longer, but also more interesting and informative. Moreover people with a higher level of education are happier also. In this aspect the purpose of the article is to determine the relationship between the quality of education, the degree of economic freedom, the level of income and the feeling of happiness. This paper presents results of the correlation analysis between indicators of education, income, happiness and economic freedom for 145 countries for 2018. The author of the work calculated Pearson (product-moment) correlation, the Spearman rank correlation, and Kendall’s Tau correlation in the Statistica. The analysis showed that Education Index has a strong relationship with Happiness Index, Economic Freedom of the World Index, Index of Economic Freedom and GDP. The analysis showed that education is closely related to the level of income and selfawareness of happiness. Education is also closely related to economic freedom. Also, the results of the study suggest that education not only contributes to an increase in income, but also makes persons happier.
The subject of education in the information society: cognitive identity of a media culture carrier
Authors: Pokulyta Iryna , Kolotylo Mariana
Published: March 2020

The article substantiates that the temporality of being of the subject as synchronization of communicative, cognitive demands on a person with dynamic changes of information reality, is the basis for the development of media education. It is justified that the formation of competencies of the carrier of modern culture is a difficult task, since such traits as critical thinking, free possession of judgments about content quality, preventive measures in guarantees of dangers of communicative activity and others, fall into the scope of the main threats “ leveling of important conditions of cognitive activity, multiplicity of models of communicative interaction, complex of semiotic systems of media culture, etc. Identified symptomatic cognitive features of the modern subject of information activity indicate the need for an urgent educational response, which means the formation of requirements and criteria for media literacy, a balanced approach to the consideration of temporality, procedural thinking in terms of knowledge, memory, self-identification. It is stated that mastering the semantics, topology, and navigation of the basics of audiovisual communication is an important vector of media education. The article emphasizes the importance of a comprehensive response from the education system to the civilizational challenges of the transition to the information society.
Developing critical thinking skills by students through active methods of the study of literature
Authors: Kovpik Svitlana
Published: March 2020

The paper deals with ways of developing critical thinking by means of literary works. It represents a number of analytical, searching, and cognitive tools aimed at activating thinking operations in the process of reading and interpreting fiction texts. It also focuses on the active methods of studying literary words (event analysis, fishbone structures, socionist analysis) which develop student critical thinking. The results of the research have proved that modern openness of literary education allows diversifying the ways and tools of studying linguistic and fiction “fabric” of the literary text.
The research of the effect of different question forms and their combination variability on the results of testing
Authors: Hryvko Antonina , Zhuk Yurii
Published: March 2020

The purpose of the research was to identify and study the features of the effect of four questions forms and their combination in polymorphic test on the output indicators of secondary school students’ testing. In the study, conducted in the subject field of studying native (Ukrainian) language, took part students of 8th and 9th-grades (N=164). The tools (criterion-oriented author’s tests, questionnaire) and methods of results’ analysis (factor analysis, dispersion analysis, etc.) used in the research process, made it possible to prove the existence of the effect of factor “question form” on the test scores (impact power is up to 35%), and also to determine combination of question forms that is characterized by the highest diagnostic accuracy. Results of a study indicate that it is advisable to construct a polymorphic linguistic test. The combination of the multiple-choice questions with one correct answer with using the text and constructed-response questions can ensure the clarity of output indicators of testing (with the least effect of question forms on them), in case evenly balance of these questions in the test. The disadvantages of the study are pointed out and prospects for their continuation and deepening, connected with further study of the optimal empirically valid test structure, are substantiated.
Secondary data analysis in educational research: opportunities for PhD students
Authors: Panchenko Liubov , Samovilova Nataliia
Published: March 2020

The article discusses the problem of using secondary data analysis (SDA) in educational research. The definitions of the SDA are analyzed; the statistics of journals articles with secondary data analysis in the field of sociology, social work and education is discussed; the dynamics of articles with data in the Journal of Peace Research 1988 to 2018 is conducted; the papers of Ukrainian conference “Implementation of European Standards in Ukrainian Educational Research” (2019) are analyzed. The problems of PhD student training to use secondary data analysis in their dissertation are discussed: the sources of secondary data analysis in the education field for Ukrainian PhD students are proposed, and the model of training of Ukrainian PhD students in the field of secondary data analysis is offered. This model consists of three components: theory component includes the theoretic basic of secondary data analysis; practice component contains the examples and tasks of using SDA in educational research with statistics software and Internet tools; the third component is PhD student support in the process of their thesis writing.
Suggestive techniques in music-performing training of future music art teachers: methodological aspect
Authors: Mishchanchuk Viktoriia
Published: March 2020

The article deals with the use of suggestive techniques, which by influencing the conscious and subconscious sphere of future music arts teachers through the use of verbal and non-verbal, external and internal means of influence, will contribute to the disclosure of their inner potential, the development of creative thinking as well as the realization of their abilities into the practical activities. The author defines various spheres of the suggestive techniques use, in particular, in the process of future music teachers training and provides own interpretation of the concept of “suggestive technique in the music-performing training of future music teachers”. In addition, the author offers methodological developments aimed at conducting creative music-performing activities #x201C; suggestopedic self-training of self-regulation skills along with suggestopedic method of forming the skills in artistic interpretation of a musical work, which is presented as a chain of suggestopedic classes, where each stage corresponds to a certain interpretation phase. Furthermore, it is noted that the developed methodological toolkit with the complex involvement of suggestive techniques with a number of methods, tools and approaches to art education along with the varied application of these methods in the process of students’ professional training, methods of performing reliability formation and innovative methods, provides to carry out pedagogical influence on independence as well as performing activities effectively. Admittedly, the introduction of typical suggestopedic forms of classes (concert sessions, classes involving related arts, class performances, storytelling, play sessions) into the methodological toolbox brings additional aesthetic coloring into the interpretative processes, which, in combination with the globalization of the learning material, have led to the reconsidering of musical works artistic interpretation techniques on the whole.
Selection criteria for cloud-oriented learning technologies for the formation of professional competencies of bachelors majoring in statistics
Authors: Gavryliuk Olga , Vakaliuk Tetiana , Kontsedailo Valerii
Published: March 2020

This article scientifically substantiates the criteria for the selection of cloud-oriented learning technologies for the formation of professional competencies of bachelors majoring in statistics, as well as presents the results of expert evaluation of existing cloud-oriented learning technologies by defined criteria. The criteria for the selection of cloud-oriented learning technologies for the formation of professional competencies of bachelors majoring in statistics, were determined: information-didactic, functional and technological. To implement the selection of cloud-oriented learning technologies for the formation of professional competencies of bachelors majoring in statistics, and effective application in the process of formation of relevant competencies, the method of expert evaluation was applied. The expert evaluation was carried out in two stages: the first one selected cloud-oriented learning technologies to determine the most appropriate by author’s criteria and indicators, and the second identified those cloud-oriented learning technologies that should be used in the educational process as a means to develop professional skills Bachelor of Statistics. According to the research, the most appropriate, convenient and effective cloud-oriented learning technologies for the formation of professional competencies of future bachelors of statistics by the vmanifestation of all criteria are cloud-oriented learning technologies CoCalc and Wolfram|Alpha.
Using spreadsheets as learning tools for computer simulation of neural networks
Authors: Semerikov Serhiy , Teplytskyi Illia , Yechkalo Yuliia , Markova Oksana , Soloviev Vladimir , Kiv Arnold
Published: March 2020

The article substantiates the necessity to develop training methods of computer simulation of neural networks in the spreadsheet environment. The systematic review of their application to simulating artificial neural networks is performed. The authors distinguish basic approaches to solving the problem of network computer simulation training in the spreadsheet environment, joint application of spreadsheets and tools of neural network simulation, application of third-party add-ins to spreadsheets, development of macros using the embedded languages of spreadsheets; use of standard spreadsheet add-ins for non-linear optimization, creation of neural networks in the spreadsheet environment with-out add-ins and macros. The article considers ways of building neural network models in cloud-based spreadsheets, Google Sheets. The model is based on the problem of classifying multi-dimensional data provided in “The Use of Multiple Measurements in Taxonomic Problems” by R. A. Fisher. Edgar Anderson’s role in collecting and preparing the data in the 1920s-1930s is discussed as well as some peculiarities of data selection. There are presented data on the method of multi-dimensional data presentation in the form of an ideograph developed by Anderson and considered one of the first efficient ways of data visualization.
Editorial
Authors: Bantleon Hans-Peter
Published: March 2020

Liebe Kolleginnen und Kollegen,

wir sind sehr oft im Behandlungsverlauf mit einem Bracketverlust konfrontiert oder müssen Brackets nach der Nivellierungsphase neu kleben. Da stellt sich für die BehandlerInnen die Frage, nehme ich ein neues Bracket oder gibt es spezielle Methoden der Wiederaufbereitung? Brigitte Wendl beschreibt in ihrem Artikel unterschiedliche Möglichkeiten des Recyclings.
Durchbruchstörungen bleibender Zähne – Ursachen und Ausprägung
Authors: Dürwald Juliane , Köbel Chris , Dannhauer Karl-Heinz
Published: March 2020

Dieser Artikel gibt einen Überblick über die Mechanismen der morphologischen und vertikalen Entwicklung der Zähne (=Dentition) von Milch- und permanentem Gebiss. Es wird zunächst die Physiologie des Zahndurchbruchs beschrieben. Besonderes Augenmerk wird hierbei auf die zeitliche Abfolge von Eruption bzw. Exfoliation in den verschiedenen Entwicklungsphasen (Milchdentition, permanente Dentition) gelegt, um mögliche Anomalien rechtzeitig erkennen zu können. Zahlreiche Faktoren können die Zahnkeime auf ihrem Durchbruchsweg beeinflussen. Dabei sind Prävalenz, Ausprägung und die möglichen Folgen der Anomalien des Zahndurchbruchs der 2. Dentition sehr verschieden.Es werden daher im Einzelnen für die jeweiligen permanenten Zähne mögliche Ursachen sowie typische klinische Merkmale beschrieben, die in Hinblick auf die Diagnosestellung „Durchbruchsstörung“ sensibilisieren sollen, um eine weiterführende Diagnostik und anschließende Therapie einzuleiten.
Trinken beim Sport: individuell und zielorientiert
Authors: Schröder Uwe , Wagner Günter
Published: March 2020

Eine an individuellen Schweißverlusten und der persönlichen sportlichen Zielsetzung ausgerichtete Trinkstrategie vor, während und nach der Aktivität ist ein entscheidender Faktor, um die Leistungsfähigkeit beim Sport zu unterstützen und die Regeneration zu optimieren. Konkrete Trinkempfehlungen für sportlich Aktive haben individuelle physiologische Grundbedingungen, Umgebungsfaktoren und logistische Rahmenbedingungen zu berücksichtigen.
Criteria-Based Imaging and Response Evaluation of Lymphoma 20 Years After Cheson: What is New?
Authors: Skusa Christopher , Weber Marc-André , Böttcher Sebastian , Thierfelder Kolja M.
Published: March 2020

Background The rapid progress in oncology research requires numerous new scientific publications. This article aims to provide an overview of criteria-based imaging and response evaluation of lymphoma according to the current status of knowledge. In fact, common criteria for evaluating data, especially imaging response evaluation, are essential for comparability of studies. While criteria-based classifications of solid tumors have been established for some time, there are now increasing classifications of lymphoma diseases. The purpose of this review is to describe the development of criteria-based evaluation of lymphoma diseases with a special focus on imaging up to current guidelines.

Methods Literature review based on PubMed including the languages English and German was performed. This review article includes the most important criteria-based response evaluations of lymphoma published between January 1999 and July 2019.

Results and Conclusion The two latest classifications of response evaluation of lymphoma are: The Lugano classification, which has been steadily developed over the past 20 years and has been specially adapted to technical progress, as well as the evaluation method RECIL (Response Evaluation Criteria In Lymphoma), which is based on the RECIST (Response Evaluation Criteria in Solid Tumors) classification already established for solid tumors. Significant imaging components of both classifications are the anatomical measurement and measurement of the metabolic response of the manifestation of lymphoma using positron emission tomography (PET/CT).

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Die COVID-19-Pandemie und das HNO-Fachgebiet: Worauf kommt es aktuell an?
Authors: Lüers Jan-Christoffer , Klußmann Jens Peter , Guntinas-Lichius Orlando
Published: March 2020

Die Übersichtarbeit fasst die aktuellen Erkenntnisse der Auswirkung der COVID-19-Pandemie für die Arbeit der HNO-Ärztin und des HNO-Arztes zusammen. Die aktuell diskutierte Rolle einer Anosmie oder Hyposmie als COVID-19-assoziiertes Symptom wird dargestellt. Wir diskutieren das klinische Management aller HNO-Fälle, aber insbesondere von COVID-19-erkrankten Patienten aus Sicht der HNO-Heilkunde. Ein besonderes Augenmerk gilt den Auswirkungen auf die HNO-Untersuchung und auf HNO-ärztliche Operationen.
Strength Training Induces Greater Increase in Handgrip Strength than
Wrestling Training per se
Authors: Karatrantou Konstantina , Katsoula Christina , Tsiakaras Nikos , Ioakimidis Panagiotis , Gerodimos Vassilis
Published: March 2020

This study investigated the effectiveness of a specialized strength training
program on maximal handgrip strength in young wrestlers. 72 young wrestlers (36
children: 8–10 years-old and 36 adolescents:13–15 years-old)
participated in the present study. Both age-categories were assigned into a
training group (18 children and 18 adolescents) and a control group (18 children
and 18 adolescents). The training groups, in conjunction with the wrestling
training performed a 4-month (2 sessions/week) specialized handgrip
training program. Maximal handgrip strength was evaluated pre, at the
intermediate (2 months) and at the completion of the program (4 months). Maximal
handgrip strength values increased during the intermediate and post-training
measurements compared to pre-training measurement in training and control groups
(p<0.001). No significant differences were observed on pre-training and
intermediate measurements between groups, while significant differences were
observed during the post-training measurement. Training group exhibited
significantly (p<0.01) greater maximal handgrip strength values than the
control group irrespective of age-category and hand-preference. A 4-month
handgrip strength training program, incorporated into the conventional wrestling
training, provokes greater adaptations in maximal handgrip strength than the
wrestling training per se. For greater handgrip training adaptations are
required more than 14 specialized handgrip training-sessions.
Effect of Different Iodine Concentrations on Patient-Reported Discomfort in Contrast-Enhanced Computed Tomography: A Prospective Comparative Trial
Authors: Vahldiek Janis Lucas , Schaafs Lars-Arne , Niehues Birgit K. , Hamm Bernd , Niehues Stefan Markus
Published: March 2020

Purpose Reducing contrast media injection speed while maintaining iodine flux is a promising workaround to lower or avoid contrast media-related discomfort during CT examinations. This approach demands contrast media with a higher concentration to guarantee excellent image quality. It remains unclear whether these concentration changes affect the patient’s experience. Thus, the aim of this study was to evaluate the influence of different concentrations of intravenous iodinated contrast media on patient discomfort during and after contrast media delivery.

Materials and Methods Patients were randomized to receive either Iomeprol 400 mg/ml (group A) or 300 mg/ml (group B) during routinely scheduled CT examinations at our department. The iodine delivery rate and injection time were kept constant in both groups. After examination, study subjects completed a digital questionnaire on different CM-related sensation items using digital visual analogue scales.

Results 253 consecutive patients were enrolled in a 6-month period. Most of the patients reported heat sensation in both groups (mean VAS: 5.3 mm in group A vs. 5.0 mm in group B, p = 0.5). Taste sensation also did not differ significantly between both groups (2.4 mm vs. 2.0 mm, p = 0.08). Pain sensation was reported to be significantly lower in group B patients (1.3 mm vs. 1.0 mm, p = 0.005), even though pain sensation in general was reported on a very low level. Other injection-related sensations were rarely reported.

Conclusion Patient-reported discomfort during intravenous injection of high-concentration contrast media (400 mg/ml) was low and only marginally different when compared to the injection of contrast media with a lower concentration. The injection of highly concentrated contrast media showed comparable overall patient acceptance, allowing a reduction of the injection speed and volume during examinations.

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Visualization of Electronic Health Record Data for Decision-Making in Diabetes and Congestive Heart Failure
Authors: Fischer Shira H. , Safran Charles , Gajos Krzysztof Z. , Wright Adam
Published: March 2020

Objective The aim of this study is to study the impact of graphical representation of health record data on physician decision-making to inform the design of health information technology.

Materials and Methods We conducted a within participants crossover design study using a simulated electronic health record (EHR) in which we presented cases with and without visualized data designed to highlight important clinical trends or relationships, followed by assessment of the impact on decision-making about next steps for patients with chronic diseases. We then asked whether trends were observed and about usability and satisfaction using validated usability questions and asked open-ended questions as well. Time to answer questions was also collected.

Results Twenty-one primary care providers participated in the study, including five for testing only and sixteen for the full study. Questions about clinical assessment or next actions were answered correctly 55% of the time. Regarding objective trends in the data, participants described noticing the trends 85% of the time. Differences in noticing trends or difficulty level of questions were not statistically significant. Satisfaction with the tool was high and participants agreed strongly that it helped them make better decisions without adding to the time it took.

Discussion The simulation allowed us to test the impact of a visualization on clinician practice in a realistic setting. Designers of EHRs should consider the ways information presentation can affect decision-making.

Conclusion Testing visualization tools can be done in a clinically realistic context. Providers desire visualizations and believe that they help them make better and faster decisions.
ELEKTRONISCHE PATIENTENAKTE: Das letzte Wort hat der Patient
Authors: Doelfs Guntram
Published: March 2020

Das Bundesgesundheitsministerium erhöht erneut die Schlagzahl bei der Einführung der elektronischen Patientenakte. Im Gesetzentwurf für ein „Patientendaten-Schutzgesetz“ (PDSG) formuliert das BMG klare Regeln zur Datenhoheit des Patienten, setzt der Gematik und der Selbstverwaltung detaillierte Fristen – und ermöglicht erstmals die Datenspende.
APPS AUF REZEPT: Kassen fordern strengere Kriterien
Authors: Kucera Martin
Published: March 2020

Das Digitale-Versorgung-Gesetz (DVG) legt fest, dass Apps künftig von Krankenkassen bezahlt werden müssen, wenn ein Arzt sie verschreibt. Unter welchen Voraussetzungen, erläutert das Bundesgesundheitsministerium in einem Referentenentwurf, der seit Mitte Januar vorliegt. Die Kassen haben Nachbesserungsbedarf angemeldet.
ARZNEIMITTELTHERAPIESICHERHEIT: Luft nach oben
Authors: Ehrhardt-Joswig Jana
Published: March 2020

Nach wie vor ist die Zahl der Medikationsfehler in Deutschland zu hoch. Insbesondere wenn multimorbide Patienten mehrere Arzneimittel gleichzeitig einnehmen, können Ärzte den Überblick verlieren und falsche Medikamente verschreiben. Elektronische Verordnungssysteme bis hin zu komplett digitalisierten Medikationsprozessen mit einem Stationsapotheker als Manager versprechen Abhilfe.
REFORM DER NOTFALLVERSORGUNG: Im Zentrum des Notfalls
Authors: Kohrs Jens
Published: March 2020

Mit der Reform der Notfallversorgung hat sich Jens Spahn ganz bewusst auf vermintes Terrain begeben. Diskutiert wird seit langem – und mit vollem Einsatz. Der Minister will, dass sein Gesetz bis Ende des Jahres verabschiedet ist, doch auch der Referentenentwurf hat wieder heftige Gegenwehr erzeugt. Vor allem die DKG ist auf den Barrikaden.
ONLINE-VIDEOSPRECHSTUNDE: Untersuchung aus der Distanz
Authors: Lang Michael
Published: March 2020

Mit dem Ausstieg aus dem Fernbehandlungsverbot eröffnen sich für Ärzte und Patienten während der Patient Journey neue Kommunikationsmöglichkeiten in Form von Online-Videosprechstunden. Unternehmensberater und Innovationsmanager Moritz E. Behm spricht im Interview über die zahlreichen Möglichkeiten, die sich daraus für Krankenhäuser ergeben.
DATENVERWALTUNG: Wer keine Digitalisierungsstrategie hat, verliert
Authors: Kempe Lisa
Published: March 2020

Die drei Klinik-Einkaufsgemeinschaften P.E.G., Prospitalia und Sana Einkauf und Logistik haben gemeinsam ein Tool für die Verwaltung elektronischer Artikelstammdaten entwickelt. Mit dem Ergebnis – dem Healthcare Content Data Portal (HCDP) – sind die drei 2019 an den Start gegangen. Wir sprachen darüber mit Benedikt Bumm von der P.E.G.
KLINIKBAU: „Keine Änderungen während der Bauphase“
Authors: Kucera Martin
Published: March 2020

Nicht selten gerät ein Krankenhausbau ins Stocken. Für solche Fälle gibt es Experten, die die Baustelle wieder in Gang bringen sollen. Im Gespräch mit kma spricht der Baurevisor Gregor Kindermann über seine Erfahrungen und verrät, wie sich solche Verzögerungen bereits im Vorfeld vermeiden lassen.
Tin-doped methylammonium lead chloride perovskites yield improved performance
Authors: Liebendorfer Adam
Published: March 2020

Partially replacing toxic lead with tin up to 33% results in better crystallinity and reduced bandgap in this perovskite material.
Entrainment of mammalian motile cilia in the brain with hydrodynamic forces
Authors: Pellicciotta Nicola , Hamilton Evelyn , Kotar Jurij , Faucourt Marion , Delgehyr Nathalie , Spassky Nathalie , Cicuta Pietro
Published: March 2020

Motile cilia are widespread across the animal and plant kingdoms, displaying complex collective dynamics central to their physiology. Their coordination mechanism is not generally understood, with previous work mainly focusing on algae and protists. We study here the entrainment of cilia beat in multiciliated cells from brain ventricles. The response to controlled oscillatory external flows shows that flows at a similar frequency to the actively beating cilia can entrain cilia oscillations. We find that the hydrodynamic forces required for this entrainment strongly depend on the number of cilia per cell. Cells with few cilia (up to five) can be entrained at flows comparable to cilia-driven flows, in contrast with what was recently observed in
Chlamydomonas
. Experimental trends are quantitatively described by a model that accounts for hydrodynamic screening of packed cilia and the chemomechanical energy efficiency of the flagellar beat. Simulations of a minimal model of cilia interacting hydrodynamically show the same trends observed in cilia.
The interplay of avatar identities, self-efficacy, and language practices
Authors: Chen Julian ChengChiang
Published: March 2020

This study intends to examine English as a foreign language (EFL) learners’ attitudes toward practicing English in
Second Life (SL) and to unpack the effects of avatar identities on EFL learners’ sense of self-efficacy and language practices.
Nine EFL learners worldwide participated in a task-based course in SL, using avatars to carry out SL-related tasks while
interacting with peers and the teacher via voice chat. Qualitative data were triangulated from multiple sources: learner
reflective journals, a post-course survey, and semi-structured interviews. Three major themes emerged: (1) the effects of masked
identity on learning, (2) the impact of telepresence and copresence on learning, and (3) the perceived attitudes toward avatar
affinity. Findings implicate that the avatar form renders masked identities to safeguard learners’ self-efficacy and empower their
language practices. It also opens up a research avenue on the impact of avatar identities on language learning and teaching in 3D
virtual environments.
Coherence relations across speech and sign language
Authors: Crible Ludivine , Gabarró-López Sílvia
Published: March 2020

This paper provides the first contrastive analysis of a coherence relation (viz. addition) and its connectives across a sign language (French Belgian Sign Language) and a spoken language (French), both used in the same geographical area. The analysis examines the frequency and types of connectives that can express an additive relation, in order to contrast its “markedness” in the two languages, that is, whether addition is marked by dedicated connectives or by ambiguous, polyfunctional ones. Furthermore, we investigate the functions of the most frequent additive connective in each language (namelyetand the sign SAME), starting from the observation that most connectives are highly polyfunctional. This analysis intends to show which functions are compatible with the meaning of addition in spoken and signed discourse. Despite a common core of shared discourse functions, the equivalence betweenetand SAME is only partial and relates to a difference in their semantics.
Terahertz electro-optical multi-functional modulator and its coupling mechanisms based on upper-layer double graphene ribbons and lower-layer a graphene strip
Authors: Liu Zhimin , Gao Enduo , Zhang Xiao , Li Hongjian , Xu Hui , Zhang Zhenbin , Luo Xin , Zhou Fengqi
Published: March 2020

A terahertz multifunction modulator composed of upper-layer double graphene ribbons and lower-layer a graphene strip, which can generate a Fano resonance produced by hybrid between a broad mode and a narrow mode, is proposed to realize electro-optical switch and filtering function. The electric field distribution, hybrid theory, and quantum level theory are all employed to explain the Fano resonance, whose transmission spectra are fitted by coupled mode theory. In comparison to other graphene-based terahertz modulators, the amplitude modulation degree can reach 99.57%, meaning an excellent electro-optical switch can be realized. Moreover, the extinction ratio of Fano resonance can reach 99.70%, demonstrating an unparalleled electro-optical filter is implemented. Finally, variations in the lateral and longitudinal lengths of the lower-layer a graphene strip enable excellent dual-band, triple-band filters. Thus, this work provides a new way to implement terahertz multi-function modulators.
Classical evolution in quantum systems
Authors: Sperling J , Walmsley I A
Published: March 2020

We investigate quantum effects in the evolution of general systems. For studying such temporal quantum phenomena, it is paramount to have a rigorous concept and profound understanding of the classical dynamics in such a system in the first place. For this reason, we derive from first principles equations of motions that describe the classical propagation in quantum systems. A comparison of this classical model with the actual temporal quantum behavior enables us to identify quantum phenomena in the system’s dynamics and distinguish them from static quantum features at individual points in time. For instance, we show how Newton’s second law emerges as a special case of our general treatment, connecting it to a Schrödinger-type equation. As applications of our universal technique, we analyze nonlinear optical processes, semiclassical models, and the multipartite entanglement dynamics of macroscopic ensembles.
Influence of systematic variations of the stimulation profile on responses evoked with a vestibular implant prototype in humans
Authors: Crétallaz Céline , Boutabla Anissa , Cavuscens Samuel , Ranieri Maurizio , Nguyen T A Khoa , Kingma Herman , Van De Berg Raymond , Guinand Nils , Pérez Fornos Angélica
Published: March 2020

Objective. To explore the impact of different electrical stimulation profiles in human recipients of the Geneva-Maastricht vestibular implant prototypes. Approach. Four implanted patients were recruited for this study. We investigated the relative efficacy of systematic variations of the electrical stimulus profile (phase duration, pulse rate, baseline level, modulation depth) in evoking vestibulo-ocular (eVOR) and perceptual responses. Main results. Shorter phase durations and, to a lesser extent, slower pulse rates allowed maximizing the electrical dynamic range available for eliciting a wider range of intensities of vestibular percepts. When either the phase duration or the pulse rate was held constant, current modulation depth was the factor that had the most significant impact on peak velocity of the eVOR. Significance. Our results identified important parametric variations that influence the measured responses. Furthermore, we observed that not all vestibular pathways seem equally sensitive to the electrical stimulus when the electrodes are placed in the semicircular canals and monopolar stimulation is used. This opens the door to evaluating new stimulation strategies for a vestibular implant, and suggests the possibility of selectively activating one vestibular pathway or the other in order to optimize rehabilitation outcomes.
SGM: a novel time-frequency algorithm based on unsupervised learning improves high-frequency oscillation detection in epilepsy
Authors: Migliorelli Carolina , Bachiller Alejandro , Alonso Joan F , Romero Sergio , Aparicio Javier , Jacobs-Le Van Julia , Mañanas Miguel A , San Antonio-Arce Victoria
Published: March 2020

Objective. We propose a novel automated method called the S-Transform Gaussian Mixture detection algorithm (SGM) to detect high-frequency oscillations (HFO) combining the strengths of different families of previously published detectors. Approach. This algorithm does not depend on parameter tuning on a subject (or database) basis, uses time-frequency characteristics, and relies on non-supervised classification to determine if the events standing out from the baseline activity are HFO or not. SGM consists of three steps: the first stage computes the signal baseline using the entropy of the autocorrelation; the second uses the S-Transform to obtain several time-frequency features (area, entropy, and time and frequency widths); and in the third stage Gaussian mixture models cluster time-frequency features to decide if events correspond to HFO-like activity. To validate the SGM algorithm we tested its performance in simulated and real environments. Main results. We assessed the algorithm on a publicly available simulated stereoelectroencephalographic (SEEG) database with varying signal-to-noise ratios (SNR), obtaining very good results for medium and high SNR signals. We further tested the SGM algorithm on real signals from patients with focal epilepsy, in which HFO detection was performed visually by experts, yielding a high agreement between experts and SGM. Significance. The SGM algorithm displayed proper performance in simulated and real environments and therefore can be used for non-supervised detection of HFO. This non-supervised algorithm does not require previous labelling by experts or parameter adjustment depending on the subject or database considered. SGM is not a computationally intensive algorithm, making it suitable to detect and characterize HFO in long-term SEEG recordings.
An extract of protein pili and filtrat of human spermatozoa: A chemical review
Authors: Sukarjati S , Kusuma P S W , Binawati D K
Published: March 2020

This study aims to determine the effect of E. coli pili protein, filtrate media culture of E. coli and mixture of E. coli pili protein and E. coli filtrate on the motility and vitality of human sperm in an in vitro. The method for obtaining E. coli pili protein is E. coli prepared by do culture on TCG media to grow E. coli pili, then cutting the Pili E. coli using Omni mixer. Pili that has been obtained then dialysis, electrophoresis and electroelution. E. coli filtrate was obtained by the method of culturing E. coli on Mc Conkey media for 48 hours and then doing culture on BHI media for 48 hours. E. coli culture on BHI media was then centrifuged. E. coli cultures in BHI media were centrifuged and the supernatant produced from centrifugation was filtered using a. 0.22µm milipore filter. 10 samples of normal donor sperm according to 1999 WHO criteria, in preparation using Percoll method. Spermatozoa were incubated with E. coli pili protein, E. coli filtrate and a mixture of E. coli pili proteins and E. coli filtrate on U-base microplate. Incubation was performed for 1 hour. Observations by calculating the motility and vitality of spermatozoa each at 100 spermatozoa under a light microscope. Data analysis was done with SPSS. The results of this study found that Protein Pili E. coli, E. coli filtrate and a mixture of E. coli pili proteins and E. coli filtrate had significant effect on sperm motility (p = 0.000) and on sperm vitality (p = 0.000). Thus it can be concluded that E. coli pili protein and E. coli filtrate are potentially used for spermicidal materials.
Milk quality of Etawa crossbred dairy goat fed combination of fermented oil palm fronds, Tithonia (Tithonia diversifolia) and Elephant Grass (Pennisetum Purpureum)
Authors: Jamarun N , Pazla R , Zain M , Arief A
Published: March 2020

The aim of this research was to determine the influence of Fermented Oil Palm Fronds (FOPF) by Phanerochaete chrysosporium with Tithonia (T) and Elephant Grass (EG) as roughage on milk quality of Etawa Crossbreed Dairy Goats (ECDG). This study used a randomized complete design consisting of four treatment groups that is: T1 = 20% FOPF+16% T+64% EG, T2 = 20% FOPF+32% T+48% EG, T3 = 20% FOPF+48%T+32% EG and T4 = 20% FOPF+64% T+16% EG. Four replicates were used per treatment. The data were analysed using Analysis of Variance (ANOVA) and differences among the treatment means were tested using Duncan’s Multiple Range Tests (DMRT) with 5 replications and 1% confidence intervals. Parameters measured were quality of milk, i.e. protein, fat, lactose and mineral (Ca and P) content. Results showed using combination FOPF by phanerochaete chrysosporium with T and EG can significantly increase milk mineral concentration (Ca and P) (p<0.01), but there was no effect on milk content of protein, fat and laktosa (p>0.05). The combination FOPF by Phanerochaete chrysosporium with Tithonia (T) and Elephan Grass (EG) can be used as an alternative feed for goats. The best feed for dairy goats was 20% FOPF + 64 % T+ 16 % EG (Treatment D).
Mixed formula of neem leaves extract and curcumin as botanical insecticides for sustainable agriculture
Authors: Joeniarti E , Purwanti S , Hidayati S , Nurlina N
Published: March 2020

Neem extract possess important bioactivities such as insect repellent, antifeedant, growth inhibitor, and other insecticidal properties, while curcumin has many bioactivities as antioxidant, antiinflamation, antibacterial, as well as anticancer. Both natural substances were mixed as botanical insecticides formula. Its efficacy against bean pod sucking bugs in vitro were evaluated. Several stages were done in this research, i.e. neem leave extraction, curcumin extraction, mixed formula production, and efficacy evaluation of mixed formula against bean pod sucking bugs in laboratory. The result of research showed that the mixed formula of the botanical insecticides containing neem leaves extract and curcumin caused mortality of bean pod sucking bugs in vitro significantly. The mortality percentage of bugs was up to 96, 25%. Therefore, it is emphasized that mixed formula of botanical insecticides containing natural substances is an eco-friendly product for agriculture.
Oral supplementation of the Extract of Fish oil to reduce fasting blood Glucose and Endothel damage but not Malondialdehyde level in diabetic male Wistar Rat (Rattus norvegicus)
Authors: Sahadewa S , Durry F D , Pangkahila W , Pinatih G N I
Published: March 2020

The main target of hyperglycaemia is endothelial dysfunction involving pathways; protein kinase activation, hexosamine activation, polyol activation, and Advanced Glycation End Products (AGEs) formation, trigger reactive radical superoxide (O2•-) to stress oxidative. Malondialdehyde (MDA) is an end product of lipid peroxidation in body and is an indicator of oxidant-antioxidant level in diabetic patients. Fish oil composing mostly omega 3 as an antioxidant can reduce oxidative stress and hyperglycaemic condition. This study aimed to investigated the effects of omega-3-rich fish oil in lowering blood sugar levels, inhibiting oxidative stress and aortic endothelial cell damage in diabetic rat models. This study was an experimental study using post-test only control group design. Thirty-two rats divided into two study groups (n = 16 individuals per group), including the diabetic rat’s group (as control) and the diabetic rats group given fish oil doses of 300 mg/kilogram body weight/day. Provision of fish oil was performed for 28 days used Blackmores® fish oil. Blood sugar and malondialdehyde levels were analyzed by spectrophotometric method. The number of aortic endothelial cells was analyzed by haematoxylin-eosin staining. Comparability test showed that the average number of fasting blood glucose level after treatment in both groups showed highly significant differences (p=0.00). Although MDA level was reduced in treatment group than control group, but statistically not significantly difference, p=0.43. Comparability test showed that average of endothelial cell between control and treatment group significantly different (p=0.00). It was concluded that fish oil supplementation containing omega-3 in diabetic rats can lower blood glucose level and can inhibit endothelial cell damage.
Effect of oyster mushroom (Pleurotus ostreatus) to the mice longissimus dorsi muscle: A chemical review
Authors: Puspitasari R L , Pambudi A , Pangeran M H
Published: March 2020

Objective of the research was to determine potency of oyster as mice nutrition growth. Oyster from market, oyster which harvested from ganyong waste biomass, and 6 weeks old male DDY strain mice were used for this research. The mushroom powder dissolved in distilled water then inserted orally force-fed 0.5 mL. There were 5 groups of treatments were dosage 200 mg/kgBW of oyster from market, without mushroom, dosage 100 mg/kgBW of mushroom from biomass waste of ganyong, dosage 200 mg/kgBW, and dosage 300 mg/kgBW. Parameters measured were histology and perimeter Longissimus dorsi muscle. The results showed histology analysis with higher dosage of mushroom solution could effect a better growth of Longissimus dorsi muscle.
The synergistic effects of 1, 2-epoxy-3 (3-(3, 4-dimethoxyphenyl)-4H-1-benzopiran-4on) propane and doxorubicin on breast cancer culture cell line
Authors: Dewi M K , Rusmartini T , Sobandi A F , Yuniarti L
Published: March 2020

Breast cancer is the second leading cause of death due to the low success rate of cancer treatment. Breast cancer therapy has not been maximized that encourage researchers to look for effective and selective cancer drugs. The purpose of this study was to determine at the synergistic effects of 1, 2-epoxy-3(3-(3, 4-dimethoxyphenyl)-4H-1-benzopiran-4on) propane (EPI) and doxorubicin on breast cancer cell cultures. This research is an experimental study in vitro, with a randomized study design post-test only control group design. The subject of this study was a T47D breast cancer cell culture, grown in a growth media with optimum time and incubation conditions. T47D are morphologically continuous cell lines like epithelial cells taken from breast tissue of a woman affected by ductal carcinoma. Cultures were performed using 30 wells, each well consisted of 1 x 106 cells. The results presented in the form of IC 50 using the Microculture Tetrazolium Salt (MTT) method and Combination index (CI) using compusyn software. An MTT method is a colorimetric assay based on cell metabolic activity. The results showed that the MTT method produced IC50 EPI values of 21.06μg/mL and doxorubicin 10.3μg/mL. EPI compounds in a combination of high concentrations have a CI below 1 (synergistic), whereas at high concentrations have CI above 1 (antagonistic). The conclusion of this study is that EPI compounds have weak anticancer in breast cancer and are synergistic with doxorubicin.