bluuebunny/crossref_metadata_2025 huggingface dataset:
Viscoelastic Study of Hemostasis Disorders Associated with Echis ocellatus Envenoming in North Benin Using a Quantra Analyzer
Authors: Larréché Sébastien , Chacha Roland Benes , Sodjinou Noé , Ouorou Seidou Alassane , Ganhouingnon Eric , Layo Edith Aloukoutou , Mégarbane Bruno , Massougbodji Achille , Chippaux Jean-Philippe
Published: December 2024

Echis ocellatus envenomings are a public health problem in West Africa, leading to bleeding and hypocoagulability. The aim of this study was to assess the hemostasis disorders associated with E. ocellatus envenoming. Envenomed patients with an abnormal whole blood clotting test (WBCT) were prospectively included at Tanguiéta, Benin. A WBCT with a sequential reading (i.e., at 20, 30, and 60 min), viscoelastic analysis (VA) using the Quantra analyzer, and blood count were performed on admission. VA and the WBCT were also assessed at 4, 8, 12, 24, 48, and 72 h after antivenom administration. Nineteen patients were included. On admission, the main results were an absence of a clot on VA and a slight decrease in platelets. Clot time gradually decreased over time while clot stiffness, fibrinogen, and platelet contributions to stiffness increased. Sequential reading improved the sensitivity of the WBCT. At H48, all patients with recurrence bleeding after antivenom administration had an abnormal WBCT while patients with a normal WBCT never had bleeding during their follow-up. VA allows the identification of various hemostasis disorders. Hypofibrinogenemia was the main disorder that persisted for several days after treatment. A WBCT with a sequential reading is an effective alternative for monitoring hypocoagulability in the absence of a laboratory.
Safety and Efficacy of Incorporating Actellic® 300 CS into Soil Wall Plaster for Control of Malaria Vectors in Rural Northeastern Uganda
Authors: Owalla Tonny Jimmy , Okurut Emmanuel , Ssaka Kenneth , Apungia Gonsaga , Cemeri Barbara , Akileng Andrew , Ojakol Basil , Paine Mark J. I. , Ismail Hanafy M. , Egwang Thomas G.
Published: December 2024

Indoor residual spraying (IRS) and the use of insecticide-treated bednets for malaria vector control have contributed substantially to a reduction in malaria disease burden. However, these control tools have important shortcomings including being donor-dependent, expensive, and often failing because of insufficient uptake. We assessed the safety and efficacy of a user-friendly, locally tailored malaria vector control approach dubbed “Hut Decoration for Malaria Control” (HD4MC) based on the incorporation of a WHO-approved insecticide, Actellic® 300 CS, into a customary hut decoration practice in rural Uganda where millions of the most vulnerable and malaria-prone populations live in mud-walled huts. Three hundred sixty households were randomly assigned to either the HD4MC (120 households), IRS (120 households) or control group without any wall treatment (120 households). Entomological indices were assessed using pyrethrum spray catching, CDC light traps and human landing catches. The Actellic® 300 CS toxicity on acetylcholinesterase activity among applicators of HD4MC was evaluated using the Test-mate (Model 400) erythrocyte acetylcholinesterase (AChE) test V.2, whereas toxicity in household occupants was monitored clinically. The Actellic® 300 CS level in house dust was analyzed using reversed-phase high-performance liquid chromatography (RP-HPLC). Entomological indices were compared between the three study arms at 1.5, 3 and 6 months post-intervention. HD4MC- and IRS-treated huts had a significantly reduced malaria vector density and feeding rate compared to control huts. There was no significant reduction in acetylcholinesterase activity at 1.5 and 24 h post exposure. Actellic® 300 CS exposure did not result in any serious adverse events among the household occupants. In conclusion, HD4MC was safe and had comparable efficacy to canonical IRS.
Mapping the Transition of Adolescents to Adult HIV Care: A Mixed-Methods Perspective from the Cape Town Metropole, South Africa
Authors: Petinger Charné , van Wyk Brian , Crowley Talitha
Published: December 2024

(1) Background: Globally, an estimated 1.7 million adolescents (aged 10–19 years) were living with HIV in 2023, with 82% residing in sub-Saharan Africa. For ALHIV, transitioning to adult care involves assuming responsibility for their own health and disease management, posing significant challenges to persistent engagement in care. There is a paucity in health policies guiding this transition in many sub-Saharan African countries. Overburdened and poorly functioning health systems struggle to provide optimal care for ALHIV amidst the rising HIV pandemic in this priority population. (2) Methods: This study employed a mixed-methods design, comprising a descriptive qualitative study with healthcare workers and managers and a cross-sectional survey to examine the practices and pathways in which the transition to adult HIV care occurs in the Cape Town Metropole, South Africa. (3) Results: We delineate three distinct ways in which transition occurs (transfer-only, adolescent-friendly, and supportive transition). A successful transition involves a sufficient level of self-management of their chronic condition and healthcare journey, which is preceded by adequate preparation pre-transition, and the monitoring of engagement post-transition. This ideally requires developing relevant health policies and implementing guidelines signaling political will and providing the impetus and agency of implementation at the service level in South Africa.
Studying Impacts of Urban Impermeability on Fear of Crime Using the Space Syntax Method; The Kuruçeşme Neighborhood as the Case Study
Authors: Soleimani Meysam , Golabi Maryam
Published: December 2024

The complex relationship between crime and urban permeability is evident in the models of CPTED. Access restriction has been considered as a design strategy to reduce crime rates. The present study investigates the impact of impermeability on fear of crime in Kuruçeşme, a historic neighborhood in Bursa. Space Syntax is applied to evaluate the configurational relationship between the neighborhood and the city through correlation analysis of connectivity (local) and integration (global) measures. By choosing the least correlated segments in the scatter plot diagram, two incompatible areas are identified: areas with “excessive permeability” (locally permeable with low global accessibility) and areas with “severe impermeable” (globally accessible with low local permeability). These areas are assessed through semi-structured, in-depth interviews, allowing inhabitants to express their thoughts about and experiences of the fear of victimization. The findings reveal that physical cues perceived as signs of danger are different in public areas characterized with excessive permeability or severe impermeability. The former suffers from a lack of “natural surveillance” and physical disorders, while the latter engenders extreme “territoriality”, resulting in social incivilities. The research underscores that urban impermeability heightens the fear of victimization by changing the configurational features of a neighborhood and manipulating mechanisms of crime prevention.
Epidemiological and Molecular Investigation of Feline Panleukopenia Virus Infection in China
Authors: Wen Yinghui , Tang Zhengxu , Wang Kunli , Geng Zhengyang , Yang Simin , Guo Junqing , Chen Yongzhen , Wang Jiankun , Fan Zhiyu , Chen Pengju , Qian Jing
Published: December 2024

The feline panleukopenia virus (FPV) is a highly contagious virus that affects cats worldwide, characterized by leukopenia, high temperature and diarrhea. Recently, the continuous prevalence and variation of FPV have attracted widespread concern. The aim of this study was to investigate the isolation, genetic evolution, molecular characterization and epidemiological analysis of FPV strains among cats and dogs in China from 2019 to 2024. The 41 FPV strains, including 38 feline strains and 3 canine strains, were isolated from rectal swab samples by inoculating monolayer FK81 cells and performing a plaque purification assay. The viral and hemagglutination titers of these 41 FPV strains were 104.33~106.33 TCID50/0.1 mL and 7.0 log2~9.7 log2, respectively. Based on the complete VP2 gene, the nucleotide homology of these FPV strains was 98.91~100%, and the homology with 24 reference FPV strains from different countries and hosts was 98.85~100%. The phylogenetic analysis revealed that 41 FPV strains were more closely related to the FPV strains of Asian origin (Asian FPV strain group) than those of European and American origin (European and American FPV strain group). Furthermore, 12 mutation sites of the VP2 protein were found in these FPV strains, of which 91 and 232 amino acid sites were previously reported. Moreover, the 91 amino acid site was found to be a positive selection site with the highest dN/dS value in the selection pressure analysis. Importantly, 35 FPV strains with 91S substitution in the VP2 protein (FPV-VP2-91S strains) had formed obvious evolutionary branches in the Asian FPV strain group. The analysis of all available VP2 protein sequences of Chinese FPV strains in the GenBank database showed that the occurrence rate of FPV-VP2-91S strains had been increasing from 15.63% to 100% during 2017~2024, indicating that the FPV-VP2-91S substitution in the VP2 protein was a noteworthy molecular characteristic of the dominant FPV strains in China. These results contribute to a better understanding of their genetic evolution and renew the knowledge of FPV molecular epidemiology.
Analysis of MLKL, RIP1 and RIP3 Immunostaining Markers in Human Liver Tissue from Fatal Yellow Fever Cases: Insights into Necroptosis
Authors: Miranda Vanessa do Socorro Cabral , Falcão Luiz Fabio Magno , Fuzii Hellen Thais , Carvalho Marcos Luiz Gaia , Lopes Jeferson da Costa , Filho Arnaldo Jorge Martins , Cruz Ana Cecilia Ribeiro , Azevedo Raimunda do Socorro da Silva , Sousa Jorge Rodrigues de , Wakimoto Mayumi Duarte , Vasconcelos Pedro Fernando da Costa , Quaresma Juarez Antônio Simões
Published: December 2024

Necroptosis is a regulated form of cell death implicated in several pathological conditions, including viral infections. In this study, we investigated the expression and correlation of necroptosis markers MLKL, RIP1 and RIP3 in human liver tissue from fatal cases of yellow fever (YF) using immunohistochemistry (IHC). The liver samples were obtained from 21 YF-positive individuals and five flavivirus-negative controls with preserved liver parenchymal architecture. The cases underwent histopathological analysis, followed by tissue immunostaining with the immunohistochemical method of streptavidin–biotin peroxidase. Using the in situ method, we evaluated the centrilobular zone (Z3), midzonal zone (Z2), periportal zone and portal tract (PT) of human liver parenchyma with markers for necroptosis, RIPK1, RIPK3 and MLKL. A quantitative analysis revealed a significantly higher expression of MLKL, RIP1 and RIP3 in the liver parenchyma of YF cases compared to controls in different zones (Z3, Z2, Z1) and portal tracts (PTs) of the liver, especially in zone 2. Immunostaining confirmed the localization of MLKL, RIP1 and RIP3 in hepatocytes and inflammatory infiltrates, highlighting their involvement in the pathogenesis of YF. A Pearson correlation analysis demonstrated significant correlations among necroptosis markers, which indicates their coordinated regulation during YF-induced liver injury.
Newcastle Disease Virus Displaying an Ectodomain of Middle East Respiratory Syndrome Coronavirus Spike Protein Elicited Robust Humoral and Cellular Immunity in Mice
Authors: Prasopsiri Jaturawitt , Srisutthisamphan Kanjana , Liwnaree Benjamas , Jengarn Juggragarn , Kramyu Jarin , Hansoongnern Payuda , Muangsanit Papon , Tanwattana Nathiphat , Kaewborisuth Challika , Sungsuwan Suttipun , Jongkaewwattana Anan , Wanasen Nanchaya
Published: December 2024

Background: Middle East Respiratory Syndrome Coronavirus (MERS-CoV) causes severe respiratory illness in humans and currently lacks an approved vaccine. The Newcastle disease virus (NDV) vector is a well-established, safe, and effective platform for vaccine development. With recent advancements in stabilizing coronavirus spike proteins to enhance their antigenicity, this study aimed to determine whether modifications to the MERS-CoV spike protein could improve its presentation on NDV particles, allowing the resulting virus to be used as an inactivated vaccine. Methods: We codon-optimized the gene encoding the ectodomain of the MERS-CoV spike protein and incorporated modifications at the S1/S2 and S2’ cleavage sites, along with a proline substitution at residues V1060-L1061. This modified spike gene was inserted into the NDV genome to create the NDV-SMERS virus. After purification and inactivation, the vaccine’s immunogenicity was assessed in mice. Results: Mice immunized with the inactivated NDV-SMERS vaccine developed robust anti-spike IgGs, neutralizing antibodies, and cellular immune responses. The study demonstrated that modifications to the MERS-CoV spike protein were essential for its effective presentation on NDV particles. Additionally, the spike gene insert remained stable through five egg passages, confirming the vector’s stability. Conclusions: Engineering the MERS-CoV spike protein is crucial for its successful display on NDV particles. The strong immune responses elicited by the NDV-SMERS vaccine in mice highlight that NDV is a promising, safe, and effective platform for MERS-CoV vaccination.
A Pool of Bacterium-like Particles Displaying African Swine Fever Virus Antigens Induces Both Humoral and Cellular Immune Responses in Pigs
Authors: Huang Jingshan , Wu Hongxia , Gao Tianqi , Zhai Huanjie , Moon Assad , Song Xin , Li Shuwen , Lu Zhanhao , Lan Jing , Zhong Dailang , Zhang Xinyu , Qiu Hua-Ji , Li Yongfeng , Sun Yuan
Published: December 2024

Background/Objectives: African swine fever (ASF), caused by African swine fever virus (ASFV), poses a significant threat to the global swine industry. This underscores the urgent need for safe and effective ASF vaccines. Methods: Here, we constructed five bacterium-like particles (BLPs) that each display one of the five ASFV antigens (F317L, H171R, D117L, B602L, and p54) based on the Gram-positive enhancer matrix-protein anchor (GEM-PA) system. GEM is a bacterial particle that contains only peptidoglycan, while PA is composed of three lysin motifs (Lysm) derived from the C-terminus of the AcmA protein, capable of non-covalently binding to GEM. By fusing the ASFV antigens with PA, the ASFV antigens can be firmly attached to the surface of GEM. Subsequently, the piglets were immunized via intramuscular injection with a mixture of BLPs-F317L, BLPs-H171R, BLPs-D117L, BLPs-B602L, and BLPs-p54. Results: The results showed that the piglets developed detectable serum IgG antibodies 2 weeks after the first immunization, and these high antibody levels were maintained 4 weeks after the booster immunization. Moreover, these piglets produced more IFN-γ-producing lymphocytes than the control piglets. Conclusions: The data indicate that the generated BLPs mixture can stimulate both humoral and cellular immune responses in piglets, these five ASFV proteins are promising antigens, and the BLPs generated represent candidate ASF vaccines.
Seventh-Degree Polynomial-Based Single Lane Change Trajectory Planning and Four-Wheel Steering Model Predictive Tracking Control for Intelligent Vehicles
Authors: Lai Fei , Huang Chaoqun
Published: December 2024

Single lane changing is one of the typical scenarios in vehicle driving. Planning a suitable single lane changing trajectory and tracking that trajectory accurately is very important for intelligent vehicles. The contribution of this study is twofold: (i) to plan lane change trajectories that cater to different driving styles (including aspects such as safety, efficiency, comfort, and balanced performance) by a 7th-degree polynomial; and (ii) to track the predefined trajectory by model predictive control (MPC) through four-wheel steering. The growing complexity of autonomous driving systems requires precise and comfortable trajectory planning and tracking. While 5th-degree polynomials are commonly used for single-lane change maneuvers, they may fail to adequately address lateral jerk, resulting in less comfortable trajectories. The main challenges are: (i) trajectory planning and (ii) trajectory tracking. Front-wheel steering MPC, although widely used, struggles to accurately track trajectories from point mass models, especially when considering vehicle dynamics, leading to excessive lateral jerk. To address these issues, we propose a novel approach combining: (i) 7th-degree polynomial trajectory planning, which provides better control over lateral jerk for smoother and more comfortable maneuvers, and (ii) four-wheel steering MPC, which offers superior maneuverability and control compared to front-wheel steering, allowing for more precise trajectory tracking. Extensive MATLAB/Simulink simulations demonstrate the effectiveness of our approach, showing improved comfort and tracking performance. Key findings include: (i) improved trajectory tracking: Four-wheel steering MPC outperforms front-wheel steering in accurately following desired trajectories, especially when considering vehicle dynamics. (ii) better ride comfort: 7th-degree polynomial trajectories, with improved control over lateral jerk, result in a smoother driving experience. Combining these two techniques enables safer, more efficient, and more comfortable autonomous driving.
Comparative Studies of Regeneration and Single Batch Design for the Properties of Basic Blue-41 Removal Using Porous Clay and Porous Acid-Activated Heterostructures
Authors: Al-Madanat Osama Y. , Popoola Saheed A. , Altarawneh Rakan M. , Alraddadi Thamer S. , Alam Mohd Gulfam , Al Dmour Hmoud , Kooli Fethi , Said Musa A.
Published: December 2024

In this investigation, the parent clay mineral montmorillonite (Mnt) was acid activated using sulfuric acid (H2SO4) at a specific mass of acid to clay mineral of 0.2 (A-Mnt) prior to the preparation of the porous clay heterostructure precursor. The derived porous acid-activated clay heterostructure (PACH) exhibited properties different from those of the conventional one (PCH). The synthesized materials were characterized using different physiochemical techniques, such as X-ray fluorescence (XRF), powder X-ray diffraction (XRD), thermogravimetric analysis (TA), 29Si MAS-NMR, nitrogen adsorption–desorption, and acidity using cyclohexylamine (CHA) as a probe molecule. The PACH had a surface area of 890 m2/g and an acidity of 0.56 mmol of protons/g. An evaluation of PCH materials was conducted to assess their effectiveness in removing basic blue 41 (BB-41) from aqueous solutions. The removal process was analyzed based on the initial concentration and pH of the BB-41 solution, and the amount of solid used, employing a batch approach. The removal efficiency was found to be greater at higher pH values, specifically between six and nine. Using the Langmuir model, the maximal removal capabilities of the studied materials were determined to be between 274 and 300 mg/g. According to the results of the regeneration tests, PACH materials could still be employed after seven cycles with a 25% efficiency loss and a 50% efficiency loss for PCH materials. Utilizing the Langmuir model equations and mass balance, a single-stage batch design was suggested to estimate the required masses to remove BB-41 at different percentages from a starting concentration of 200 mg/L.
Integrating Graph Data Models in Advanced Water Resource Management: A New Paradigm for Complex Hydraulic Systems
Authors: Qiao Jiabin , Shen Keyan , Xiao Wenzhe , Tang Jiarun , Chen Yurun , Xu Jing
Published: December 2024

The efficient management of water resources is crucial due to increasing environmental and societal pressures, requiring advanced data handling capabilities. Traditional relational data models, while foundational, struggle to capture the complex relationships inherent in water systems, limiting analytical and decision-making effectiveness. To address these challenges, this paper proposes a comprehensive graph data model for water resource management. Our model includes conceptual, logical, and physical frameworks that enable the structured representation of hydraulic objects and their relationships. We categorize hydraulic objects, examine their spatial, structural, and operational interconnections, and construct an adaptable graph data model. This model provides the enhanced integration, mining, and analysis of hydraulic data, supporting intelligent, data-driven water management applications. Example applications demonstrate the model’s utility in improving watershed management, hydropower scheduling, and uncovering latent relationships among hydraulic components through graph neural networks. This work establishes a robust data foundation for the sustainable and scientific management of water resources.
Monsoonal Extreme Rainfall in Southeast Asia: A Review
Authors: Chen Yixiao , Teo Fang Yenn , Wong Soon Yee , Chan Andy , Weng Chunying , Falconer Roger A.
Published: December 2024

In recent years, extreme rainfall and related disasters, including floods and landslides, have led to significant property damage and loss of life globally. Southeast Asia (SEA) is particularly impacted by these rainfall-driven events. This study reviews research development and approaches to understand the current status of monsoonal extreme rainfall in SEA, with the importance of the impacts of natural and anthropogenic factors. Natural factors, including the individual and combined effects of various climatic phenomena, such as Madden–Julian Oscillation (MJO), El Niño–Southern Oscillation (ENSO) and cold surges (CSs), have significant impacts on rainfall patterns. Anthropogenic factors, including emissions and changes in land use, also play a crucial role in producing extremes. This review identifies key challenges, such as the uncertainty in both available rainfall datasets and climate models, emphasising the needs for climate model improvement and better adaptation to complex regional climatic and geographical environments. The findings enhance understanding and response strategies to extreme rainfall events and mitigate the associated negative impacts.
Bibliometric Analysis of Per- and Polyfluoroalkyl Substances (PFASs) from 2000 to 2023 Based on Web of Science Database
Authors: Yin Zixuan , Li Cui , Li Xingyang , Wang Chongqing
Published: December 2024

Perfluorinated and polyfluoroalkyl substances (PFASs) have been extensively used in many fields since the 1950s due to their distinctive chemical stability. PFASs are becoming emerging pollutants, and they have attracted special attention all over the world because of environmental persistence, bioaccumulation, and potential toxicity. Through bibliometric analysis, this study provides a visual analysis of 6055 articles about PFASs in the Web of Science database from 2000 to 2023. Research on PFASs can be divided into two stages, 2000–2014 and 2015–2023, and the number of publications and the frequency of citations increase rapidly in the latter stage. Studies on PFASs are highly interdisciplinary, mainly focusing on the cluster of ecological and environmental, involving environmental science, environmental engineering, and toxicology. The authors of the articles come from 106 countries, with the United States and China being the most productive contributors. However, China has a relatively low number of citations per article. A total of 2634 institutions have participated in the studies, and institutions from USA are outstanding. An analysis of author cooperation shows that authors from the USA lead in publication output and research activity. Some Chinese authors rank among the top contributors, but there is a need for stronger international cooperation. Keyword clusters and burst analysis reveal the key areas of research in PFASs, including chemical classification, environmental behavior, health effects, and removal methods. This study provides a comprehensive perspective on the study of PFASs, offering valuable insights into emerging trends and serving as a critical reference for future research, policy development, and technological innovation.
Optimization of Water and Land Allocation in Fruit Orchards over a 20-Year Period
Authors: Quezada Luciano , Holzapfel Eduardo , Kuschel-Otárola Mathias , Lillo-Saavedra Mario , Rivera Diego , Souto Camilo , Lagos Octavio , Palma Diego
Published: December 2024

This study proposes a nonlinear programming model for the optimization of water and land allocation in a 1000 ha orchard over a 20-year period to maximize farmers’ net profits. Different scenarios were evaluated, including equitable and unrestricted land allocation, and the risks associated with fruit production were considered. Additionally, a sensitivity analysis that focused on the variability of labor and water availability was conducted. The results reveal that with equitable land allocations and no constraints on the cultivated area, cherry emerges as the most profitable crop, although there are large risks associated with its price volatility. The introduction of risk and land allocation constraints highlights the importance of crop diversification in mitigating economic risks. A sensitivity analysis indicated that reductions in water and labor availability significantly affect the optimal cropping pattern of an orchard, suggesting that the efficient and adaptive management of resources is required. The proposed optimal cropping pattern maintains the economic viability of the orchard even with 70% and 24% reductions in water and labor, respectively. This approach underscores the importance of implementing resilient and sustainable agricultural strategies to ensure food security and increase economic stability in the face of changing climatic and labor conditions.
A Novel Double-Coated Persulfate Slow-Release Material: Preparation and Application for the Removal of Antibiotics from Groundwater
Authors: Hu Zhixin , Xia Yujin , Zhang Miao , Xie Yilin , Dong Luyu , Bi Qingquan , Wang Yunfei , Wang Xueli , Yang Shengke
Published: December 2024

Single-layer slow-release materials have short lifespans due to their rapid initial release behavior. To address this problem, a double-coated persulfate slow-release material was developed in this study. The outer coating layer consists of polycaprolactone–silica sand, which is used to encapsulate an inner layer of polycaprolactone–silica sand and sodium persulfate. Static and dynamic release experiments were conducted to analyze the behavior and degradation capabilities of this material when activated by iron–nitrogen co-doped biochar (Fe@N-BC) for the removal of sulfamethoxazole (SMZ) and ciprofloxacin (CIP) in groundwater. The double-coated material maintains a stable release rate, achieving optimal performance with an outer layer thickness of 0.25 cm and a silica sand to polycaprolactone (PCL) mass ratio between 2 and 5. Optimal degradation rates for SMZ and CIP were observed at a pH of 3. Specifically, 1 mg/L of SMZ was fully degraded within 12 h, while the complete removal of 1 mg/L of CIP occurred within just 2 h. The presence of humic acid and higher initial pollutant concentrations reduced the degradation rates. Among the tested anions, HCO3− had the most significant inhibitory impact, while Cl− had the least significant impact on degradation performance. Column experiments demonstrated a consistent release of persulfate over a period of 60 days at a flow rate of 0.5 mL/min. Increased flow rates resulted in a shorter lifespan for this slow-release material. The minimum outflows of SMZ and CIP were obtained with a quartz sand mesh size of 40–60 and a flow rate of 0.5 mL/min. These results offer a theoretical basis for the prolonged and stable release of persulfate, as well as the efficient removal of SMZ and CIP from groundwater.
Autonomous Vehicle Acceptance in China: TAM-Based Comparison of Civilian and Military Contexts
Authors: Wan Dan , Peng Ling
Published: December 2024

In this study, a comparative analysis is conducted on the public acceptance of autonomous vehicles (AVs) in civilian and military contexts among the Chinese public. In order to identify the key factors influencing AV adoption under different scenarios, a Technology Acceptance Model (TAM) framework was applied in combination with an extended variable of perceived risk. Also, a structured questionnaire was designed, with 1004 valid responses received from a sample comprising mainly members of the Chinese public aged 31–50. Data analysis was conducted through reliability and validity tests, correlation analysis, and Structural Equation Modeling (SEM). Despite some slight variations in acceptance level between civilian and military fields, overall public attitudes are relatively consistent, according to the analytical results. Specifically, the average behavioral intention is slightly stronger and more consistent among the public in the civilian context, with higher scores achieved with respect to perceived usefulness and perceived risk in the military context, indicating a stronger emphasis on functionality and safety in military applications. As confirmed by SEM path analysis, there are significant influences exerted on behavioral intention by perceived usefulness, perceived ease of use, and satisfaction. These results demonstrate a high level of public acceptance of AV technology among the Chinese public in the context of policy support and technological innovation, providing empirical insights into the development of scenario-specific promotion strategies for the effective application of AV in various settings.
The Role of Collector-Drainage Water in Sustainable Irrigation for Agriculture in the Developing World: An Experimental Study
Authors: Mirzaqobulov Jakhongirmirzo , Mehta Kedar , Ilyas Sana , Salokhiddinov Abdulkhakim
Published: December 2024

This study investigates the feasibility of using mineralized collector-drainage water (CDW) for irrigating maize crops on light gray soils in the Syrdarya region of Uzbekistan, an area facing severe water scarcity and soil salinity challenges. The research is particularly novel as it explores maize production in marginalized soils, a subject previously unexamined in this context. The experiment was designed as a three-factor factorial study with three replications, following the guidelines of the Uzbekistan Cotton Scientific Research Institute. Five irrigation treatments (Fresh Water, Fresh Water 70% vs. CDW 30%, Complex Method (Mixing with Specific Rules), CDW 70% vs. Fresh Water 30% (Mixing) and only CDW) were evaluated using an Alternate Furrow Irrigation system, incorporating various mixtures of fresh water and CDW to determine their effects on soil salinity, crop health and yield. The amount of irrigation water required was determined using a soil moisture balance model, with soil samples collected at multiple depths (0–100 cm) to monitor changes in moisture content and salinity. Salinity levels and soil health parameters such as alkalinity, chloride, sulfate and cation/anion balances were measured at different stages of crop growth. Data were collected over three growing seasons (3 years). An analysis of the data revealed that using CDW, even in mixtures with fresh water, can sustain crop production while managing soil salinity. Notably, irrigation methods such as Mixing 70–30 and the Complex Mixing Method effectively reduced freshwater dependency and maintained the crop yield without significantly increasing salinity. The results suggest that CDW could be a viable alternative water source in regions where traditional water resources are limited. The findings have significant implications for improving water use efficiency and agricultural productivity in areas facing similar environmental challenges. This research not only contributes to the broader understanding of sustainable irrigation practices in arid regions but also provides a scientific basis for the wider adoption of CDW in Uzbekistan, potentially enhancing food security and supporting long-term agricultural sustainability in the region.
Changes in the brain rhythm indices of cyclic sports athletes During the neurofeedback course
Authors:   FSBI «North-Caucasian Federal Research-Clinical Center of the Federal Medical and Biological Agency», Essentuki, Russian University of Sports «GTSOLIFK», Moscow, Russian Federation, Lunina N. V. , Koryagina Yu. V. ,   FSBI «North-Caucasian Federal Research-Clinical Center of the Federal Medical and Biological Agency», Essentuki, Russian Federation;
Published: December 2024

Objective. Reveal peculiarities of changes in the brain rhythm indices in cyclic sports athletes during the biofeedback course.
Material and methods. The study involved male athletes, 18–22 years (n=410), the main group (MG, n=387) included the athletes, who underwent the beta rhythm neurofeedback course (10 sessions), the control group (CG, n=23) did not undergo
the course. Brain rhythm changes were examined with the EEG indices: alpha ( %), beta ( %), theta ( %) rhythms. Each session included graphic (10 minutes) and game (16 minutes) sections with audiovisual biofeedback. The electrodes were placed bipolarly (Fz-Cz points, the 10–20 system). Muscle tension was recorded with myographic markers on the forehead above the supraorbital arches. Main task — to voluntary raise the beta rhythm level above the set threshold against the background of muscle relaxation.
Results. In the background EEG activity, the MG athletes had the following brain rhythm distribution: α — 27 (25; 30) %, β — 30 (28; 35) %, θ — 41 (34; 45) % with reduced values of the θ/β index (1.58 (1.1; 1.95 c.u.). In the CG, theta rhythm prevails: α — 27 (16; 38) %, β — 25 (22; 50) %, θ — 40 (34; 48) % with reduced values of the θ/β index (1.97 (1.31; 3.33) c.u.). After the course, the rhythm structure in the main group revealed a prevalent fast activity (β — 45.5 (31; 57) %) with a reduction of the very low activity (θ — to 36 (24; 36) %) and an alpha rhythm reduction to 21 (17; 26.04) %. The θ/β index (c.u.) has also reduced (p>0.05). In the CG, the very low activity has increased by 15 % (θ — 46 (40; 55) %).
Conclusion. The changes have shown a trend towards mobilization and optimization with increased fast (β) activity against the background of reduced very slow (θ) activity.
Epidemiologic characterization of arterial hypertension cases in children living in the monsoon climate of Primorsky Krai
Authors:   State Budgetary Healthcare Institution «Regional Children Clinical Hospital No. 2», Vladivostok, Russia, Ryzhenenkova I. N. , Koneva E. S. ,   Federal State Autonomous Educational Institution of Higher Education «First Moscow State Medical University named after I. M. Sechenov» of the Ministry of Healthcare of the Russian Federation (Sechenov University), B. V Petrovsky Russian Research Center of Surgery Moscow, Russia, Zakharov S. N. ,   Federal State Autonomous Educational Institution of Higher Education «First Moscow State Medical University named after I. M. Sechenov» of the Ministry of Healthcare of the Russian Federation (Sechenov University), Moscow, Russia, Zhumanova E. N. ,   JSC «Medsi Group of Companies», Federal State Budgetary Institution of Higher Education «Russian University of Medicine» of the Ministry of Healthcare of the Russian Federation, Moscow, Russia, Pesoyskaya A. A. ,   Federal State Autonomous Educational Institution of Higher Education «First Moscow State Medical University named after I. M. Sechenov» of the Ministry of Healthcare of the Russian Federation (Sechenov University), Moscow, Russia
Published: December 2024

Objective. Тo provide an epidemiological characteristic of cases of arterial hypertension in children living in the monsoon climate of Primorye.
Material and methods. The article provides an epidemiological characteristic of cases of arterial hypertension in children permanently residing
in the monsoon climate of Primorye.
Results. In our study, children with arterial hypertension in the monsoon climate of Primorye show significant and persistent changes in their psychological status, their adaptive capacity is reduced, both to social and physical factors; significant changes in autonomic homeostasis are also noted.
Conclusion. At present, it is necessary to continue studying the characteristics of the course of arterial hypertension in children permanently residing in the monsoon climate of Primorye, in order to develop effective strategies for the treatment, prevention and rehabilitation of this condition in this group of people, due to the fact that there are scientifically substantiated data on the use of various physical factors for the prevention of weather-dependent reactions and the treatment of arterial hypertension.
Biofeedback technologies in the correction of post-stroke gait and balance disturbances in patients with psychoemotional disorders
Authors:   State Autonomous Healthcare Institution of the City of Moscow "Moscow Scientific and Practical Center for Medical Rehabilitation, Restorative and Sports Medicine named after S.I. Spasokukotsky of the Moscow Department of Health, Moscow, Russia, Filippov M. S. , Kostenko E. V. ,   State Autonomous Healthcare Institution of the City of Moscow "Moscow Scientific and Practical Center for Medical Rehabilitation, Restorative and Sports Medicine named after S.I. Spasokukotsky of the Moscow Department of Health, Moscow, Russia; Federal State Autonomous Educational Institution of Higher Education "Russian National Research Medical University named after N.I. Pirogov" of the Ministry of Health of the Russian Federation., Petrova L. V ,   State Autonomous Healthcare Institution of the City of Moscow "Moscow Scientific and Practical Center for Medical Rehabilitation, Restorative and Sports Medicine named after S.I. Spasokukotsky of the Moscow Department of Health, Moscow, Russia, Pogonchenkova I. V. ,   State Autonomous Healthcare Institution of the City of Moscow "Moscow Scientific and Practical Center for Medical Rehabilitation, Restorative and Sports Medicine named after S.I. Spasokukotsky of the Moscow Department of Health, Moscow, Russia
Published: December 2024

Objective. This study aimed to assess how combining and separately using programmable functional electrical stimulation (FES) and stabilometric biofeedback training (BFB) impacts the emotional wellness and quality of life in individuals experiencing mobility impairments following an ischemic stroke.
Material and methods. The research included 160 participants who were in the residual phase post-stroke, with an average duration since stroke of 2.52 ﾁ}1.32 years. All patients received a standard standard medical rehabilitation (MR). The first group, considered the main group, comprised 40 patients who received FES and BFB-stabilometric training. Comparison group 1 consisted of 40 patients who only received FES, while comparison group 2 included 40 patients who underwent BFB-stabilometric training exclusively. The control group included 40 patients who received only a standard rehabilitation package. Evaluation of motor impairments was conducted using several assessment tools, including MRCS, MAS, Tinetti, Berg balance scale, and a 10.meter walking test. Emotional state changes were measured using the Hospital Anxiety and Depression Scale, and quality of life was assessed through the EQ-5D-5L Questionnaire.
Results. Implementing FES and BFB-stabilometric training significantly enhanced balance, improved emotional conditions, and raised the quality of life for patients. Incorporating biofeedback technologies into the post-stroke rehabilitation protocol can significantly enhance the recovery of motor functions, emotional status and elevate patientsﾁf quality of life.
ANALYSIS OF PRIMARY TRAFFIC ACCIDENT DATA AS A TOOL TO IMPROVE THE EFFICIENCY OF TRANSPORT AND LOGISTICS SYSTEMS
Authors:   Belgorod State Technological University, Bychkova Kristina Alexandrovna , Podkopaev Anton Valerievich ,   Belgorod State Technological University, Bulatova Olga Yurievna ,   Don State Technical University, Linnik Yuri Nikolaevich ,   State University of Management
Published: December 2024

The article presents the need to develop effective innovative methods of intelligent analysis and prevention of emergency situations against the background of an increase in the number of road accidents (RA). The purpose of this study is to analyze primary data on road accidents in order to improve the efficiency of intelligent transport systems (ITS). The analysis of the initial data on road accidents was based on the relationship between the collection of the necessary information from various sources, such as statistical reports, photo and video recording cameras, geographic information systems and network analysis. The results of scientific research in the field of traffic management show that the combination of analytics of primary data on road accidents in ITS serves not only to improve safety on the street and road network, but also to effectively rank road resources associated with road accidents.
OPTIMISATION OF LOGISTIC MODEL OF FREIGHT TRANSPORT BY CARGO VEHICLES
Authors:   State University of Management, Moscow Automobile and Road State Technical University (MADI), Karelina Maria Yuryevna , Linnik Yuri Nikolaevich ,   State University of Management, Akulov Alexey Andreyevich ,   State University of Management, Moscow Automobile and Road State Technical University (MADI), Soloviev Nikolay Vladimirovich ,   Soloviev Nikolay Vladimirovich State University of Management, Moscow Automobile and Road State Technical University (MADI)
Published: December 2024

This article explores the complexities of freight forwarding networks and their spatial significance in relation to global economic trends. The technological and economic aspects of transport hubs and their impact on the distribution of goods are discussed. The importance of terminal classification in modelling and its role in accurately representing transport logistics nodes is discussed. The transport logistics node (TLN) module is investigated, focusing on node characteris-tics and the use of origin-destination (OD) matrices to create modules incorporating transport and goods variables. Further empirical research is proposed to gather additional information on transport logistics nodes, which is a key aspect to improve the accuracy and efficiency of freight transport models and refine estimates associated with interventions in the wider transport system.
DEVELOPMENT OF A MODEL OF A MULTIMODAL PASSENGER TRANSPORTATION NETWORK, ON THE EXAMPLE OF VOLGOGRAD
Authors:   Volgograd State Technical University, Kulikov Alexey Viktorovich
Published: December 2024

The article analyzes the indicators of the functioning of the urban passenger transport system using the example of a million-plus city. The number of routes and the volume of passengers transported in 2023 in Volgograd has been determined. It is proposed to develop 29 large transport hubs on the territory of the city, ensuring the interaction of various passenger transport for multimodal transportation. Multimodal transport hubs are formed on the basis of a previously developed methodology. The scheme of the transport network model is represented by the interaction of urban passenger transport on the territory of Volgograd in the form of vertices and edges. The paper examines the distribution of routes by transport hubs. A model of the transport network has been developed that characterizes the relationship of multimodal transport hubs with all types of urban passenger transport. The possibility of organizing multimodal transportation on the developed network is considered.
DETERMINATION OF CONSUMPTION RATES OF SPARE PARTS FOR SCHEDULED PREVENTIVE REPAIR OF FLEET OF A TRANSIT AGENCY
Authors:   Moscow Automobile and Road Construction State Technical University (MADI), Krylov Grigory Аleksandrovich , Pozhivilov Nikita Vasilevich ,   Moscow Automobile and Road Construction State Technical University (MADI)
Published: December 2024

The issue of determining the consumption rate of spare parts for scheduled preventive maintenance of rolling stock of a motor transport enterprise is considered. A method for deter-mining the consumption rate based on calculating the gamma-percentage resource of the component in question is proposed. As a result, it was proposed to calculate the consumption rate of such spare parts as the sum of the consumption rate based on the frequency of the vehicle's mileage and the additional consumption rate in the event of failures.
Evaluating the protective effect of a nanoemulsion containing propolis and Nigella sativa nanoparticles on enamel surface
Authors: Khanabadi Hedieh , Hamze Faeze , Amiri Mahnaz , Behzadi Sepideh , Emami Razavi Hanieh Sadat , Karimi Mehrdad
Published: December 2024

Background: Due to the lack of data, the current study aims to determine the protective effect of a nanoemulsion containing Nigella sativa (NS) and propolis extract (comparing the macroscale and nanoscale form) on the mineral content of enamel after tooth brushing. Methods: In this experimental study, six human premolars were sectioned buccolingually, and the specimens were randomly divided into four groups. These groups were treated with nanoemulsion alone, nanoemulsion accompanied by propolis in either bulk or nanoparticle form, and distilled water (as a control). The treatment procedure was seven consecutive days, in which the specimens were etched and brushed daily. The Ca and P content of the enamel surface was quantified by Scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM/EDX), and the surface roughness was recorded by a profilometer. Moreover, the SEM micrographs of the specimens were captured. Ultimately, the data were analyzed using one-way ANOVA with LSD post hoc analysis (α=0.05). Results: The Ca and P content of the groups were significantly different (P=0.000 and P=0.000), but the difference in the surface roughness of the experimental groups was not significant (0.27). Conclusion: The beneficial effect of NS+propolis as a barrier on tooth surface was confirmed. However, its effect on the mineral content of enamel needs further assessment.
Evaluation of sleep quality in patients with trigeminal neuralgia
Authors: Baghaei Saman , Lavaee Fatemeh , Roosta Azadeh
Published: December 2024

Background: This cross-sectional study evaluated the relationship between sleep disturbance levels and trigeminal neuralgia (TN) from 2019 to 2020 in the School of Dentistry of Shiraz University of Medical Sciences. Methods: Forty-nine patients under treatment for TN referring to the Department of Maxillofacial Medicine of the School of Dentistry of Shiraz University of Medical Sciences, who were chosen according to availability sampling, were included in the study, and 40 healthy persons were also recruited for the control group. The Persian version of the Pittsburgh Sleep Quality Questionnaire (PSQI) was used to evaluate the participants’ sleep disturbance. The final results were compared using the chi-square test, and more than 95% reliability was reflected as significant (P<0.05). Results: The mean age was 56.89±10.93 for the TN participants and 37.12±9.55 for the control group. The sleep disturbance of patients with TN was meaningfully higher in comparison with the control group (P<0.0001). The mean level of sleep disturbances in each group between men and women was insignificantly different (P>0.05). However, the mean level of sleep disturbance of women and men in the TN group was meaningfully higher than that of the men and women in the control group (P=0.001). The mean level of sleep disturbance was higher in TN patients only in the age range of 41–50 years (P=0.02). Conclusion: The patients with TN had meaningfully lower levels of sleep quality than the control group.