bluuebunny/crossref_metadata_2025 huggingface dataset:
Circulating microRNAs in the prediction of BAV aortopathy: do the expression patterns correlate between blood and aortic tissue?
Authors: Naito Shiho , Sequeira-Gross Tatiana , Petersen Johannes , Detlef Inken , Sachse Marco , Zeller Tanja , Reichenspurner Hermann , Girdauskas Evaldas
Published: February 2022

Background: The limitation of aortic size-based criteria is gradually recognized in the prediction of aortic events especially in bicuspid aortic valve (BAV) cohorts, while most aortic events happen in patients with proximal aortic diameters <50 mm. Circulating microRNAs (miRs) have been addressed as a novel tool to improve risk stratification in patients with different aortopathies. We aimed to elucidate the correlation between peripheral whole blood and aortic tissue miRs in order to prove the potential availability as a biomarker in the clinical routine. Methods: All patients who received elective aortic valve repair/replacement ± proximal aortic replacement to BAV disease (n = 65, 2013–2018) were prospectively included. The expression of 10 miRs (miR-1, miR-17, miR-18a, miR-19a, miR-20a, miR-21, miR-106a, miR-133a, miR-143 and miR-145) was analyzed in the intraoperatively acquired aortic tissue as well as in the peripheral blood before the surgery. Results: We found a significant correlation between circulating miRs in the peripheral blood and aortic tissue levels of miR-21 (r = 0.293, p = 0.02), miR-133a (r = 0.43, p = 0.02), miR-143 (r = 0.68, p < 0.001), and miR-145 (r = 0.68, p < 0.001). Further, the multivariate logistic regression analysis revealed an association between blood and aortic tissue miR-143 levels each other (Odds Ratio [OR] 1.29, 95% Confidence Interval [CI] 1.11–1.67, p = 0.02; OR 1.36, 95% CI 1.19–2.01, p = 0.03, respectively) and a blood/aortic miR-143 level to dilated aorta (OR 3.61, 95% CI 1.62–9.02, p = 0.01; OR 2.92, 95% CI 1.81–7.05, p = 0.02, respectively). Conclusions: Our study demonstrates a significant correlation between peripheral whole blood and aortic tissue miRs, confirming the hypothesis that circulating miRs may reflect remodeling processes in the proximal aorta in bicuspid aortopathy patients.
Advanced heart failure: state of the art and future directions
Authors: Masarone Daniele , Kittleson Michelle , Petraio Andrea , Pacileo Giuseppe
Published: February 2022

Advanced heart failure is a clinical challenge that requires a pathophysiological-based approach. As the field has been the subject of multiple reviews, the objective of this paper is not to duplicate these publications but rather to offer practical tips for the clinical cardiologist to enable the optimal management of patients with advanced heart failure. Advanced heart failure is defined as a clinical syndrome characterized by severe and persistent symptoms, most commonly with severe ventricular dysfunction, despite optimized medical therapy. This review covers the management of the advanced heart failure patient from pharmacologic therapy with disease-modifying drugs, to the use of electrical therapy devices, percutaneous valve repair and finally to the role of left ventricular assist devices and heart transplantation. The review also explores future directions in the management of advanced heart failure, including translational perspectives for the treatment of this syndrome.
Elevated red cell distribution width and cardiovascular mortality in ASCVD risk cohorts: National Health and Nutrition Examination Survey (NHANES III)
Authors: Katamreddy Adarsh , Kokkinidis Damianos G , Miles Jeremy , Siasos Gerasimos , Giannakoulas George , Faillace Robert T
Published: February 2022

Background: Although red cell distribution width (RDW) is associated with increased cardiovascular mortality, the relationship between an elevated RDW and cardiovascular mortality among various ASCVD risk groups is unknown. Methods: We utilized the National Health and Nutrition Examination Survey (NHANES) III, which uses a complex, multistage, clustered design to represent the civilian, community-based US population. Out of 30,818 subjects whose data were entered during the 1988–1994 period, 8884 subjects over 40 years of age, representing a weighted sample of 85,323,902 patients, were selected after excluding missing variables. The ACC/AHA pooled cohort equation (PCE) was used to calculate atherosclerotic cardiovascular disease (ASCVD) risk, and low (<7.5%), intermediate (7.5–20%), and high (>20%) risk groups were created. The primary endpoint was cardiovascular mortality. A multivariate proportional hazard regression was performed using the Fine and Gray (sub-distribution) method. Red cell distribution (RDW), C-reactive protein (CRP), age, sex, race, diabetes, smoking status, high-density lipoprotein (HDL), and chronic kidney disease (CKD) were used as covariates in each of the ACC/AHA pooled cohort risk groups. Results: The adjusted hazard ratios for RDW >14 (Normal range 12.5–14.5 %) as compared to <13 were 2.79 (95% confidence intervals (95% CI) 2.77–2.81, p < 0.01), 2.02 (95% CI 2.01–2.02, p < 0.01), 1.18 (95% CI 1.18–1.18, p < 0.01) in the low, intermediate and high-risk groups respectively. The 20-year cumulative cardiovascular mortality (RDW >14 vs. <13) was 4% vs. 1.3% low, 17.7% vs. 7.7% in intermediate and 28.1% vs. 24.6% in high ASCVD risk groups respectively. Conclusion: Our findings support that measurement of RDW in the intermediate ASCVD group may be clinically valuable for further risk stratification and prognostication in the general population of people aged more than 40 years of age with regards to identifying those at an increased risk for cardiovascular mortality.
Construction of a pyroptosis-related classifier for risk prediction of acute myocardial infarction
Authors: Guo Kehang , Zhuo Zewei , Chen Pengfei , Wu Huihuan , Yang Qi , Li Jingwei , Jiang Rui , Mao Qiuxian , Chen Hao , Sha Weihong
Published: February 2022

Background: Acute myocardial infarction (AMI) is a common cardiovascular disease that has a high mortality. Pyroptosis is a programmed cell death mediated by inflammasome. It remains to be clarified on the expression pattern and risk predictive role of pyroptosis-related genes in AMI. Methods: The gene expression data were extracted from the Gene Expression Omnibus (GEO), and pyroptosis-related genes were obtained from published articles. Pyroptosis-related differential expressed genes were selected between normal and AMI samples and then we explored their immune infiltration level using CIBERSORT. Univariate Cox and LASSO regression were applied to establish a classifier based on pyroptosis-related genes. ROC analysis was utilized to evaluate the classifier. Results: In this study, we obtained 20 pyroptosis-related genes which showed differential expression in AMI and normal samples. Among the differential expressed genes, GZMB was significantly positively associated with activated NK cells (R = 0.71, p < 0.01), while NLRP3 exhibited a negative correlation with resting NK cells (R = –0.66, p < 0.01). 9 genes (NLRP9, GSDMD, CASP8, AIM2, GPX4, NOD1, NOD2, SCAF11, GSDME) were eventually identified as a predictive risk classifier for AMI patients. With the classifier, patients at high and low risk could be discriminated. Further external validation showed the high accuracy of the classifier (AUC = 0.75). Conclusions: Pyroptosis-related genes are closely related to immune infiltration in AMI, and a 9-gene classifier has good performance in predicting the risk of AMI with high accuracy, which could provide a new way for targeted treatment in AMI.
Ethical considerations in elderly patients with acute coronary syndrome
Authors: Ayesta Ana , Bonanad Clara , Díez-Villanueva Pablo , García-Blas Sergio , Ariza-Solé Albert , Martínez-Sellés Manuel
Published: February 2022

Acute coronary syndrome (ACS) is one of the main causes of mortality and morbidity in the elderly. The prevalence of ACS increases with age and patients with advanced age have some co-morbidities that require an individualized approach, which includes a comprehensive geriatric assessment. Ageism is a matter of great concern. In this scenario, some ethical conflicts may arise which should be anticipated, considered, and solved. Clinicians will need to prioritize and allocate resources, to avoid futility/proportionality, which is not always easy to assess in these patients. This review aims to summarize the evidence regarding ethical conflicts that may arise in the management of patients with ACS and advanced age. We will discuss how to choose the best option (which frequently is not the only one) with the lowest risk for harm, considering and respecting the patients’ decision. The four basic principles of bioethics (beneficence, non-maleficence, autonomy, and justice) are thoroughly reviewed, and discussed, regarding their role in the decision making process.
Evidence-based treatment of atrial fibrillation around the globe: comparison of the latest ESC, AHA/ACC/HRS, and CCS guidelines on the management of atrial fibrillation
Authors: Wolfes Julian , Ellermann Christian , Frommeyer Gerrit , Eckardt Lars
Published: February 2022

Recent versions of evidence-based guidelines on the management of atrial fibrillation (AF) have been published by the European Society of Cardiology (ESC) in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS), the American College of Cardiology, American Heart Association, and the Heart Rhythm Society (AHA/ACC/HRS), and the Canadian Cardiovascular Society/Canadian Heart Rhythm Society (CCS). As all societies refer to the same multicentric and usually multinational studies, the similarities undoubtedly outweigh the differences. Nonetheless, interesting differences can often be found in details, which are usually based on a different assessment of the same study, the availability of data in relation to the publication date and local preferences and availabilities of certain cardiovascular drugs. The following article aims at lining out these similarities and differences.
Heart injuries related to cardiopulmonary resuscitation: a risk often overlooked
Authors: Girotti Paolo , Rizzuto Antonia , Orsini Vincenzo , Hodja Vebi , Koenigsrainer Ingmar
Published: February 2022

Background: Current studies focus primarily on skeletal injuries following cardiopulmonary resuscitation (CPR). Few studies report on intrathoracic injuries (ITI) and none, to our knowledge, focus exclusively on cardiovascular injuries related to cardiac massage. This study was based on autopsy findings and assessed the incidence of non-skeletal CPR related injuries related to chest compression. Methods: This was a retrospective forensic autopsy cohort study conducted in a single institution after resuscitation. Pathologists recorded autopsy data using standardized protocol contained information from external and internal examination of the body. Results: Thirty-eight autopsy reports (21 males and 17 females), post- CPR-failure were studied. Heart lesions were reported in 19 patients (group A). The average age was 65.7 years (69.05 group A and 66.5 group B). Median weight was 75.2 Kg and was significantly higher in group B (p = 0.01). Pericardial lesions were identified in 6 patients in group A and 2 in group B (p = 0.2 ns). No significant difference was observed among the two groups (Table 4) with the exception of the average number of rib fractures which was higher in group A (p = 0.04). Autopsy findings revealed heart injuries in 50% of patients with a high prevalence (52.6%) of left ventricle injuries. Conclusion: Cardiac lesions represent frequent and serious complications of unsuccessful CPR. Correct performance of chest compressions according to guidelines is the best way to avoid these complications.
Ragam Pola Tabuhan Instrumen Gambang Pada Musik Gambang Semarang
Authors: Rachman Abdul , Teangtrong Pramot , Jirajaruphat Phakamas , Utomo Udi , Sinaga Syahrul Syah , Muchsin Ibnu Amar , Sokhiba Sabrina Firda
Published: February 2022

Gambang Semarang merupakan salah satu musik tradisi Indonesia yang tumbuh dan berkembang di kota Semarang, Jawa Tengah. Musik Gambang Semarang memiliki instrumen yang terbuat dari kayu yang menjadi ciri khas dari musik Gambang Semarang itu sendiri yaitu Gambang. Instrumen Gambang memiliki ragam pola tabuhan khas yang bias memberi nuansa pada musik Gambang Semarang. Tujuan penelitian ini adalah untuk mengetahui dan mendeskripsikan ragam pola tabuhan instrumen Gambang pada musik Gambang Semarang.  Metode penelitian yang digunakan adalah kualitatif dengan pendekatan etnomusikologi. Teknik pengumpulan data dilakukan dengan teknik observasi, wawancara, studi dokumen, dan Focussed Group Discussion. Analisis data dilakukan dengan tahapan reduksi data, klasifikasi data, dan penyimpulan.  Hasil penelitian menunjukkan bahwa  pola tabuhan instrumen gambang pada musik Gambang Semarang terdiri dari pola tabuhan gembyang nglagu oktaf, dan pola garap cengkok ajeg. Masing-masing pola tabuhan dari instrumen gambang tersebut melibatkan rangkaian nada-nada sesuai dengan seleh-nya. Karena terpengaruh seleh dari melodi lagu utama maka pola tabuhan gembyang nglagu oktaf dan pola tabuhan garap cengkok ajeg memiliki enam seleh yaitu seleh do, seleh re, seleh mi, seleh sol, dan seleh la.
Electric Potential Value of Microbial Fuel Cell Technology from Chinese Food Restaurant Waste Using Variation of Electrode Pairs
Authors: Jaya Danang , Widawati Tunjung Wahyu , Ellysa Firda , Nugroho Singgih Adi
Published: February 2022

Indonesia's rapid population growth means that power demand will continue to rise year after year. Indonesia's growing population has resulted in an increase in restaurants, including Chinese food restaurants. As the number of restaurants grows, so does the amount of waste produced. Microbial Fuel Cells (MFC) that create electrical energy are one solution to this challenge. The study aimed to explore the utilization of MFC systems for power generation. It measured the performance of MFC in liquid waste in generating electrical value by utilizing a series of electrode types, particularly Aluminum (Al), Copper (Cu), Zinc (Zn), and Lead (Pb), and a blend of the four types of electrodes. The measured electrical value indicated that MFC can produced the high electrical voltage value was the pair of zinc (anode) and copper (cathode) of (0.863 V) and then the highest electric current value is 0.14 mA with electrode Cu and Zn. The maximum power density is 0.00464 W/m2 using a combination of Zn/Cu electrodes and then electrical energy with highest value is 0.75168 J with Zn/Cu.
Monitoring of Regosol Soil Moisture with Internet of Things in Capilar Irrigation and Liquid Organic Fertilizer on Growth of Mustard Greens (Brassica rapa. L)
Authors: Saidi Didi , Charibaldi Novrido
Published: February 2022

Regosol is soil that has a low level of soil fertility and water availability. According to  internet of tings information system used to monitor soil moisture, water use will be more efficient. This study aims to apply the Internet of Things information system to monitor soil moisture in capillary irrigation and liquid organic fertilizer, study the capillary irrigation system and liquid organic fertilizer on the growth of mustard greens (Brassica rapa. L) and soil characteristics. The method used in this study was a completely randomized design (CRD) with two factors. namely Type of fertilizer, consisting of 4 levels, P0: No liquid organic fertilizer, P1: 5 liters/ha Household waste liquid organic fertilizer, P2: 5 liters/ha Biduri leaf liquid organic fertilizer, P3: 300 kg/ha NPK fertilizer. The second factor is the number of wick of capillary irrigation, consisting of 3 levels: I0: No capillary irrigation, I1: 1 wick capillary irrigation, I2: 2 wicks capillary irrigation. The results showed that the soil moisture during the growth of mustard greens was 16.59 to 23.48 %, the more capillary wicks, the higher the soil moisture. The average water requirement for mustard plant growth is 3.16 liters. Mustard plants begin to wither and lack water at 6.47 % soil moisture. Liquid organic fertilizer and capillary irrigation had a significant effect on leaf width, but had no significant effect on plant height, plant wet weight, plant dry weight, soil moisture, soil pH. Liquid organic fertilizer has a significant effect on soil C-organic and soil NPK levels, while capillary irrigation has a significant effect on water volume.
Conspiracy and Punishment in Shakespeare’s Julius Caesar
Authors: Hasan Mahmood
Published: February 2022

Abstract: This study is devoted to discussing the phenomenon of “Conspiracy” and “Punishment” in Julius Caesar (1599) according to Shakespeare’s canon. William Shakespeare has attributed to dealing with some of the concepts that confirm his piercing insight into human nature. He considers the man to be instinctive with exaggerated passion, if not guided by reason, leading to unexpected consequences affecting both the individual and the community. This study also is an attempt to deal with how the individual and society are affected by the inability of the man to deal rationally with his divided nature. It shows how men cannot mitigate the consequences of their anti-social actions because justice must be on the path. The study helps to discover the political conflicts in our present-day through reconsidering Shakespeare's political texts and referring to a “Conspiracy Theory” which leads to political and moral troubles at all times and everywhere. Thus, it is axiomatic that the law needs the support of the human moral faculty as called by psychologists a “Superego” specifically when the law fails to obtain maximum assistance, crime increases, unrest spreads, the law and order prove difficult if not impossible
العلم والمعرفة مظهر من مظاهر الحضارة العربية الاسلامية
Authors: سلمان حمود محمد
Published: February 2022

ملخص

يتحدث البحث عن دور العلم والمعرفة في الحضارة الإسلامية، ويظهر المكانة العظيمة التي حظي بها العلم والمعرفة في القران الكريم والسنة النبوية الشريفة، حتى أصبح العلم والمعرفة وجه من وجوة ومظاهر الحضارة العربية الإسلامية.

        تكون البحث من مقدمة وثلاث مباحث وختم بقائمة المصادر والمراجع، تناول المبحث تفسير الحضارة العربية وما وصلت اليها من ازدهار، ثم يبين تعاريف وتوضيح للعلم والمعرفة، وجاء المبحث الثاني بمراحل الحركة العلمية الإسلامية، ثم المبحث الثالث بأهم العلوم التي بزغت بها شمس العرب العلمية والمعرفية، ثم قائمة المصادر.
الفاظ الاضطراب والاهتزاز في القرآن الكريم دراسة دلالية
Authors: صالح مهدي إيمان
Published: February 2022

إن القرآن الكريم ميدان رحب وواسع لدراسة الألفاظ و دلالاتها الصوتية  المتنوعة .وهو مشحون بألفاظ ذات دلالة خاصة سميت بألفاظ الاضطراب والاهتزاز تشعرك أصواتها بداهة بالحركة والاهتزاز ،فإذا تبينت معانيها اللفظية والسياقية تأكد ذلك المعنى (الانطباعي البدهي) وهو أمر سنثبته عن طريق استعراض طائفة واسعة من أقوال اللغويين والمفسرين في جملة كبيرة من تلك الألفاظ التي سنعالجها في فقرات بحثنا هذا وقد تعددت مبانيها فهي تارة مكررة المقطع وتارة مكررة الصوت الواحد وتارة على بناء معين مثل فعلل. وكل  بناء مقصود في مكانه ويحمل دلالة خاصة لا ينفع تبديله بغيره ،وهذا من روائع البلاغة القرآنية .
अनुवादस्य सैद्धान्तिकस्वरूपम्
Authors: पौडेल: Poudel प्रकाश Prakash
Published: February 2022

यस्यां कस्यामपि स्रोतोभाषायां स्थितानां सामग्रीणां विषयाणां वा तदन्यलक्ष्यभाषासु रूपान्तरणप्रक्रियैवानुवादः ।अनुवादसम्बद्धं शास्त्रमनुवादशास्त्रं कथ्यते । विश्वस्मिन् ज्ञेयविषयान् सम्प्रेषयितुम्, ज्ञानस्य विस्ताराय चानुवादआवश्यकः । अनुवादो विविधाधारेण वर्गीकृतो लभ्यते । तथाऽप्यन्तरभाषिक–भाषान्तरिक–भाषेतरानुवादे हिसर्वेऽपि भेदोपभेदाः सम्मिलिता भवन्ति । अनुवादकार्ये चत्वारि चरणानि भवन्ति । यथा – अनूद्यसङ्कथनपठनम्, तस्यभाषान्तरिकविश्लेषणम्, अनुवादप्रक्रिया अनुवादसङ्घट्टनं वा, लक्ष्यभाषायां सङ्कथननिर्माणञ्चेति । एतेषु चतुर्षु चरणेषुनिर्वाहितेष्वनुवादप्रक्रिया पूर्णा भवति । कुशलेनानुवादकेन सर्वदा मध्य आगताः समस्या निराकृत्य स्रोतोभाषायाः सामग्रीणांलक्ष्यभाषाया निकटे स्थापनाय यतनीयं भवति । अतोऽनुवादो रचनायाः पुनःसंरचनं पुनरुत्पादनं वा मन्यते । अस्मिन्नध्ययनेप्रमुखतयानुवादस्य प्रकारान्, विधीन्, पद्धतीः, मान्यताश्च पुरस्कृत्य तत्सम्बद्धसैद्धान्तिकपक्षस्य च विवेचना कार्या भवति ।
The Once and Future Story
Authors: Wallis Estelle
Published: February 2022

This article analyses three key texts in Arthurian literature to illustrate the changes the myth has undergone from its popularisation in the twelfth century to its rediscovery in the nineteenth century. It compares Geoffrey of Monmouth’s unfounded insistence on historical accuracy with Chrétien de Troyes’ focus on interiority and male–female dynamics before making a leap in time to explore Lord Alfred Tennyson’s Idylls of the King and its anxieties concerning gendered power dynamics and material culture. The paper draws on these comparisons to demonstrate the malleable nature of the Arthurian myth, as well as its status as both a reflection of Western values and a focus point for the authors’ priorities within their own environments and cultures. This is achieved through a focus on social commentary and the creation of a plethora of characters and symbols that will become rooted in the European psyche.
Automatic Control System Using Arduino UNO and Web-Based Monitoring For Watering Chili Plants
Authors: Adek Rizal Tjut , Fikry Muhammad , Naluri Helmi , . Risawandi
Published: February 2022

Caring for chili plants in addition to fertilization is proper watering. Watering is sometimes done less regularly in this case is the timeliness other than that the temperature and soil moisture are not paid attention to by the chili plant keepers. Moreover, if the chili plant keeper has other activities, then the watering of the plants will be more irregular, making the production of chili plants not optimal and even chili plants can die. By utilizing Arduino and several supporting sensors, we can determine the right watering time. In this research, data is taken from sensors, such as soil moisture sensors, air humidity sensors, temperature sensors and ultrasonic sensors which then the data will be sent to the website to be displayed to the user. Sensors are devices used to detect changes in physical quantities such as pressure, force, electrical quantities, light, motion, humidity, temperature, speed and other environmental phenomena. The purpose of this study was to measure soil moisture, air humidity, temperature as a determinant of the right watering time for chili plants and make it easier for farmers to monitor and water chili plants. This is evidenced in the Blackbox testing method on the system design, from the test results it is known that this system has been running well and is in accordance with what is expected.
Design of 2x2 Wide Bandwidth MIMO Antenna For LTE And 5G Sub-6GHz
Authors: Rusdiyanto Dian , Astuti Dian Widi , Muslim Muslim , Alam Syah , Adhiyoga Yohanes Galih
Published: February 2022

In this study, the design of a 2X2 MIMO microstrip antenna was proposed for LTE and 5G Sub-6GHz applications. The antenna is designed to have a wide bandwidth operating in the frequency range of 2300 MHz to 3600 MHz. The antenna material uses FR4 substrate which has a dielectric constant of 4.6 and a thickness of 1.6 mm. To achieve a wide bandwidth, the ground length is cut. Meanwhile, to achieve the resonant frequency using the square slot method on the radiator element. Antenna design begins with designing a single element shape, then designing a 2x2 MIMO antenna. The results of the MIMO2x2 antenna simulation show that the reflection coefficient and isolation coefficient of each antenna are below -10 dB. The results of the reflection coefficient of each antenna show that the bandwidth achieved is more than 2 GHz. At a frequency of 2300 MHz, the lowest gain is 2.98 dBi, while the highest gain is 3.10 dBi. The lowest and highest gains at a frequency of 3600 MHz are 3.83 dBi and 3.87 dBi. Overall, this antenna has achieved the desired goal, which is to have a wide bandwidth and be able to operate on LTE and 5G applications.
Design and Build a Web-Based E-Lapor Application as a Citizen's Service Media
Authors: Hidayatulloh Syarif , Ramadhan Gema Wahyu
Published: February 2022

Rukun Warga 06 Jatisari Bekasi City is a government agency that has direct contact in serving residents. One of the services provided is the submission of complaints in the surrounding environment and the preparation of cover letters for various purposes. The service system provided can be said to be still conventional, and manually documented. With the current system, of course, it is still quite inconvenient for residents, especially when submitting complaints to the surrounding environment because it is not well documented so that follow-up is still not optimal. besides that, there are also problems that occur if residents want to submit a cover letter. The application of information system technology for citizen services will greatly help to make the system even better. Therefore we need an application that can be accessed anytime and anywhere to create a more optimal service. E-Lapor is a web-based application that is intended to help maximize citizen services. The application is designed using UML and built with HTML & PHP programming languages, as well as for interface design using CSS and for the database it is MySQL. Testing this application using black box and usability testing with results showing that the application is functioning properly, in accordance with the design that has been made.
Identification of Pneumonia using The K-Nearest Neighbors Method using HOG Fitur Feature Extraction
Authors: Khairina Nurul , Sibarani Theofil Tri Saputra , Muliono Rizki , Sembiring Zulfikar , Muhathir Muhathir
Published: February 2022

Pneumonia is a wet lung disease. Pneumonia is generally caused by viruses, bacteria or fungi. Not infrequently Pneumonia can cause death. The K-Nearest Neighbors method is a classification method that uses the majority value from the closest k value category. At this time people are not too worried about pneumonia because this pneumonia has symptoms like a normal cough. However, fast and accurate information from health experts is also very necessary so that pneumonia symptoms can be recognized early and how to deal with them can also be done faster. In this study, researchers will diagnose pneumonia to obtain information quickly about the symptoms of pneumonia. This information will adopt human knowledge into computers designed to solve the problem of identifying pneumonia. In this study, the K-Nearest Neighbors method will be combined with the HOG Extraction Feature to identify pneumonia more accurately. The KNN classification used is Fine KNN, Cosine KNN, and Cubic KNN. Where will be seen how the value of accuracy, precision, recall, and fi-score. The results showed that the classification could run well on the Fine KKN, Cosine KNN, and Cubic KNN methods. Fine KNN has an accuracy rate of 80.67, Cosine KNN has an accuracy rate of 84,93333, and Cubic KNN has an accuracy rate of 83,13333. Fine KNN has precision, recall and f1-score values of 0.794842, 0.923706, and 0.854442. Cosine KNN has precision, recall and f1-score values of 0.803048, 0.954039, and 0.872056. Cubic KNN has precision, recall and f1-score values of 0.73388, 0.964561, and 0.833555. From the test results, positive and negative identification of pneumonia was found to be more accurate with the Cosine KNN classification which reached 84,93333.
Augmented Reality for Topeng Malangan Face Recognition as a Media for Cultural Education
Authors: Sakaria Setiabudi , Kurniawan Aldino Wildhan
Published: February 2022

Topeng Malangan is one of Malang's original culture that needs to be preserved. However, the survey results show that 65.9% of respondents are not familiar with Topeng Malangan. Currently Topeng Malangan is less popular among the people of Malang city, because Topeng Malangan art is rarely performed and only a little introduced through dance learning in elementary schools. There are 76 Topeng Malangan figures with six famous figures, namely Raden Gunung Sari, Dewi Sekartaji, Dewi Ragil Kuning, Bapang, Panji Asmoro Bangun, and Klono Sewandono. This research produces face recognition software through Augmented Reality using a marker tracking model. Two-dimensional marker as the printed or the cellphone screen displayed figures, will be performed as a three-dimensional image of the mask face. In addition to three-dimensional images, figuring character information, text and sound are also showed according to the characteristics of the Topeng Malangan from Desa Kemantren Kecamatan Jabung, Kabupaten Malang, Jawa Timur. The blackbox testing of the application shows that all application parameters are functioning properly. This application can be used as a learning medium in the form of educational games about Topeng Malangan figures and culture
Pemanfaatan Augmented Reality Dalam Membangun Sistem Informasi Pertanahan Pasca Pendaftaran Tanah Sistematik Lengkap
Authors: Ferdiansyah Dony Ferdiansyah , Wahyono Eko Budi , Widodo Sri
Published: February 2022

Penyajian informasi kepada masyarakat di era keterbukaan informasi dan kemajuan teknologi pada revolusi industri 4.0  mengalami pertumbuhan yang sangat pesat dengan adanya media internet, sehingga dapat mengakses informasi lebih cepat dengan menggunakan smartphone. Kementerian ATR/BPN yang mengelola informasi tentang pertanahan, memiliki big data pertanahan yang besar pasca diadakannya kegiatan Pendaftaran Tanah Sistematik Lengkap sejak tahun 2017. Data tersebut harus mampu dikelola dengan baik untuk disajikan kepada masyarakat. Website berbasis WebGIS yaitu www.bhumi.atrbpn.go.id merupakan salah satu langkah dalam menyampaikan informasi pertanahan melalui tampilan pemetaan 2D. Masyarakat cukup kesulitan dalam membaca peta 2D. Hal ini menyebabkan informasi yang disajikan tidak tersampaikan dengan baik. Maka penelitian ini untuk melakukan rancang bangun aplikasi menggunakan teknologi augmented reality berbasis location-based service. Aplikasi tersebut akan dibangun melalui metode research and development dengan model prototyping. Informasi yang disajikan merupakan hasil superimposed dari dua layer yaitu persil bidang tanah dan informasi kepemilikan, jenis hak, NIB, penggunaan dan luas bidang tanah. Uji coba aplikasi tersebut dengan metode black box testing terhadap fungsionalitas aplikasi. Uji coba fungsionalitas aplikasi yang dibangun dilakukan oleh ASN dan PPNPN dari pegawai Kantor Pertanahan Kota Surabaya II dengan menyebarkan 14 pertanyaan melalui kuesioner tertutup. Hasil dari pengujian aplikasi adalah aplikasi dapat berfungsi dengan baik dan mampu menjadi salah satu sarana untuk menyajikan data pertanahan kepada masyarakat.
CUMULATIVE MODEL OF INCREASING GROSS VALUE ADDED OF THE HIGH-TECH SECTOR OF THE NATIONAL ECONOMY
Authors: IERMAKOVA О.А.
Published: February 2022

Topicality. The high-tech sector plays a crucial role in the socio-economic development of the world's states and is a key factor in their competitiveness. Ukraine is a state with a strong scientific and innovative potential, which is able to provide access to the world's leading positions. However, Ukraine lags significantly behind in the development of its high-tech sector from many other countries of the world, which requires the development of strategic measures to overcome the current situation.Aim and tasks. Based on the analysis of mutual influence of gross value added of the high-tech sector and the reproductive process of the national economy on an innovative basis to develop a conceptual basis for the formation of a system of incentives for increasing the gross value of high-tech areas of entrepreneurial activity.Research results. The article reveals the role of high-tech sector in the national economy and on this basis a cumulative model of increasing gross value of the high-tech sector of the national economy is proposed. The model reveals appropriate mutual influences and allows to approach the development of incentives for increasing the gross value of the high-tech sector from systemic positions.Conclusion. Gross value added, created by the high-tech sector, is a source of competitive advantages for the national economy: it provides a technological basis for innovation development of all sectors of the economy, workplaces for highly skilled labor, reduction of capital outflow due to the involvement of its investment in innovation activities, increase of budget revenues. Stimulating the development of the high-tech sector should be systematic and cover all elements of the cumulative model of increasing gross value added of the high-tech sector of the national economy, namely: foreign economic integration, increase of productivity of domestic industries on an innovative basis, increase financial resources for expanded reproduction of innovation potential and development of the innovation system.
Enzimas exógenas em dietas contendo farelo de trigo e outros alimentos alternativos para aves: revisão
Authors: Araujo Daniel de Magalhães , Silva José Humberto Vilar da
Published: February 2022

A nutrição de aves é uma ciência dinâmica de grande importância para a produção animal. Isto faz com que sempre haja assuntos atuais que carecem ainda de estudos mais refinados, constituindo-se em vasto campo de trabalho para os cientistas da área. Nesta revisão os autores abordam dois temas atuais: o uso de enzimas exógenas e de alimentos alternativos em nutrição de aves. Além disto, relacionam os dois temas de forma didática e compilam, à luz da literatura científica nacional e internacional, os resultados disponíveis sobre o uso de enzimas exógenas em dietas de aves, principalmente contendo alimentos alternativos.
Efeito do protocolo de sincronização de ovulação com Norgestomet e Benzoato de estradiol sobre a citologia vaginal de novilhas e vacas Nelore
Authors: Ferraz Henrique Trevizoli , Oliveira Filho Benedito Dias de , Gambarini Maria Lúcia , Lopes Dyomar Toledo , Caixeta Luciano Souza
Published: February 2022

Este estudo objetivou caracterizar o efeito do protocolo hormonal para sincronização da ovulação com progestágeno e benzoato de estradiol (BE) sobre as alterações citológicas vaginais de novilhas e vacas Nelore. Cinco fêmeas de cada categoria receberam implante auricular de norgestomet (NOR) e uma aplicação intra-muscular (IM) de 2,0 mg de BE, no dia 0 (D0). No dia 8 (D8), removeu-se os implantes e aplicou-se 0,50 mg de cloprostenol sódico, IM. No dia 9 (D9), aplicou-se 1,0 mg de BE, IM. Durante o protocolo foram coletadas amostras citológicas da mucosa vaginal com o auxílio de escovas ginecológicas e os esfregaços corados pelo método panótico. As células parabasais predominaram durante todo o período observado em ambas as categorias. As células intermediárias jovens e as superficiais anucleadas foram mais freqüentemente observadas (P<0,05) após as aplicações de BE. Portanto, a citologia vaginal apontou que nas duas categorias de fêmeas Nelore estudadas houve maior número de células basais, intermediárias jovens e superficiais anucleadas depois da aplicação de BE, no início do protocolo e predominância de células parabasais durante a permanência do implante de NOR, sob ação progesterônica. A citologia vaginal não forneceu elementos para determinação do momento da ovulação em fêmeas bovinas da raça Nelore submetidas à sincronização da ovulação.
Custo do tratamento químico de resíduos agrícolas com solução de uréia na alimentação de ruminantes
Authors: Souza Onaldo , Lages André Maia Gomes , Souza Mariah Tenório de Carvalho , Souza Wanessa Cavalcante de
Published: February 2022

Em determinadas regiões do Brasil não é propícia a exploração de ruminantes apenas com o pasto, devido a escassez na produção de volumosos em zonas áridas, necessitando intervenção técnica para o sucesso da produção animal. O Estado de Alagoas, assim como outros do Nordeste brasileiro padece todos os anos de carência de volumosos em épocas secas, afetando de forma trágica as cadeias produtivas conseqüentes da produção de ruminantes. Os nove meses de estiagem proporcionam o êxodo rural e sérios problemas sociais aos governos Municipais, Estaduais e Federal. O tratamento químico de resíduos agrícolas para uso na alimentação animal representa uma forma de alimentação alternativa, capaz de minimizar e/ou solucionar estes graves problemas e a falta de alimentos volumosos para os ruminantes, em épocas de escassez de chuvas, quando eleva o índice de mortalidade dos rebanhos, levando descrédito ao produtor rural e causando graves problemas sociais, todos os anos (SOUZA et al. 2002). Os resíduos agrícolas, representam um importante recurso forrageiro para os animais em períodos de seca, além de proporcionar a sustentabilidade ambiental, evitando as queimadas que ocorrem periodicamente. O tratamento químico com uréia é uma das melhores formas para enriquecer e melhorar o valor nutritivo destes materiais fibrosos. Os produtores de todo o território nacional têm insistentemente buscado soluções para resolver o drama da escassez de alimentos para ruminantes e a utilização de resíduos tratados quimicamente pode resolver este problema, já que a produção de cana-de-açúcar coincide com o período de escassez de forragem em determinadas regiões, por ocorrência das secas cíclicas e periódicas.
Sinopse preliminar sobre a ocorrência de siris nas regiões estuarinas do Estado do Ceará
Authors: Igarashi Marco Antonio
Published: February 2022

O ambiente estuarino é um importante e favorável local para reprodução e desenvolvimento de um grande número de siris. Várias espécies de siris ocupam a mesma área ecológica, incluindo áreas de manguezais. No Estado do Ceará, Região Nordeste do Brasil, estes animais participaram com um pequeno volume no mercado consumidor, sendo capturados por meio da pesca artesanal. O objetivo do artigo será de auxiliar no conhecimento de determinados tipos de siri que está sendo manuseado. Os seguintes siris foram identificados: Callinectes affinis (Fausto-Filho, 1980) C. bocourti (Milne Edwards, 1879), C. danae (Smith, 1869), C. ornatus (Ordway, 1863), C. exasperatus (Gerstaecker, 1856), C. larvatus (Ordway, 1863), C. sapidus (Rathbun, 1896) e Portunus spinimanus (Latreille, 1819). Esta pesquisa enfatiza a importância em desenvolver os mangues no sentido de suportar a captura de seus recursos pesqueiro tais como os siris e melhorar a economia costeira.
Hemangiossarcoma esplênico em gato: relato de caso
Authors: Trivilin Leonardo Oliveira , Nunes Louisiane de Carvalho , Porfírio Lenir Cardoso
Published: February 2022

A neoplasia esplênica de origem no endotélio vascular é extremamente maligna e raramente é relatada em felinos. Objetivou-se com o presente artigo relatar um caso de hemangiossarcoma esplênico em felino demonstrando a característica da doença bem como as formas de diagnóstico utilizadas para a conclusão do caso. Um gato macho, 13 anos, foi levado ao HOVET-UFES com dificuldade respiratória grave e rapidamente morreu. À necropsia constatou-se, por meio de achados macro e microscópicos, o acometimento por hemangiossarcoma esplênico. Embora já tenha sido citado que o hemangiossarcoma esplênico em felinos é um neoplasma de ocorrência rara, o estabelecimento do diagnóstico precoce e correto poderia auxiliar na elaboração de tratamentos mais adequados.
(G-INFASA) Totality of the Youth Movement in Treating The Economy during the Covid-19 Pandemic
Authors: Istikomah Istikomah , Nur Siti Khayisatuzahro , Fahruddin Abd. Rohman
Published: February 2022

The presence of Covid-19 has hit the community's economy. Banyuwangi as a regency that relies on the tourism sector as an economic driver has felt the impact. It resulted in the economic shock of the people of Banyuwangi. Muhammadiyah as one of the largest religious organizations in Indonesia plays an active role in community economic empowerment activities. Covid-19 also gave rise to a social response in the form of the Waste Infaq Movement (G-INFASA) from the Muhammadiyah Youth of Kalibaru Banyuwangi in the context of empowering the economy of the Kalibaru community. G-INFASA is a unique form of social response, there is a spirit of generosity and the spirit of developing Islamic philanthropy in achieving social welfare. The focus of research is the management of G-Infasa and the opportunities and challenges of G-INFASA in caring for the people's economy. The study aims to determine the role of the Muhammadiyah Kalibaru Banyuwangi Youth in empowering the Kalibaru community's economy through the development of Islamic philanthropy with waste as its asset. The method used is qualitative research with an Asset-Based Approach to Asset Based Community Development (ABCD), which in this case is waste. From the study, it was found that the management of G-INFASA in the ABCD (Asset Based Community Development) approach is supported by several aspects, namely related to community asset mapping and financial circulation analysis.
KURMA (RUTHAB) UNTUK MENCEGAH KEGUGURAN DAN MELANCARKAN PERSALINAN
Authors: Romadloniyah Nur Shinta , Oktaviani Fitrotin Nafisa , Arifin Imamul
Published: February 2022

Kandungan gizi yang terdapat dalam buah kurma dipercaya dapat digunakan untuk penguat kandungan. Tujuan dari penelitian ini adalah untuk mengetahui manfaat mengkonsumsi buah kurma bagi ibu hamil. Pada penelitian kali ini kami menggunakan jenis penelitian kuantitatif, yakni metode penelitian yang lebih menekankan pada aspek pengukuran secara objektif terhadap fenomena sosial. Lebih spesifiknya lagi metode yang digunakan adalah metode survey. Penelitian ini menggunakan teknik pengumpulan data dengan cara mewawancarai ibu hamil di daerah Gresik dan Sidoarjo serta membuat kuesioner melalui GFORM yang disebarkan ke media sosial. Berdasarkan riset yang telah dilakukan dari 56 ibu hamil dan yang sudah melahirkan, terdapat 60% wanita yang mengkonsumsi buah kurma saat hamil menyatakan bahwa buah kurma dapat menguatkan kandungan dan mempercepat proses persalianan dari tanggal perkiraan. Serta 15% wanita lainnya menyatakan bahwa diantara mereka pernah mengalami keguguran sebelum mengkonsumsi buah kurma. Cara pengolahan data dalam penelitian ini adalah dengan menggunakan analisis univariat dan analisis bivariat. Saran untuk riset kali ini diharapkan peneliti menambah jumlah informan dan lebih memahami faktor apa saja yang menyebabkan keguguran pada kandungan ibu hamil.
FAKTOR YANG BERHUBUNGAN DENGAN PENGETAHUAN REMAJA TENTANG DAMPAK PERGAULAN BEBAS PADA SISWA SISWI SMP IT NUR HIKMAH
Authors: Susanti Rosa , Sitai Fatimah Okta Zenita
Published: February 2022

Masa remaja merupakan masa transisi yang kritis sebagai kunci berkembangnya pengalaman baru yaitu usia 10-19. Masa remaja dihadapkan pada dorongan untuk mengkonsumsi alkohol, rokok, atau obat-obatan lain serta memulai perilaku pergaulan bebas. Tujuan Tujuan Penelitian adalah mengetahui faktor yang berhubungan dengan pengetahuan remaja tentang dampak pergaulan bebas pada siswa siswi SMP IT Nur Hikmah. Metode penelitian Metode penelitian adalah metode kuantitatif dengan pendekatan deskriptif. Responden penelitian ini adalah Siswa Siswi SMP IT Nur Hikmah kelas VIII dan IX. Tahap penelitian adalah tahap (i) menyebarankan kuesioner dengan menggunkan google form, tahap (2) analisis data. Data yang digunakan pada penelitian ini adalah data primer, teknik analisis yang digunakan yaitu analisis univariat dan bivariat (Uji Chi Square). Hasil penelitian didapatkan p value 0.012 menunjukan bahwa terdapat hubungan antara jenis kelamin dengan Pengetahuan Siswa Siswi SMP IT Nur Hikmah kelas VIII dan IX Tentang Dampak Pergaulan Bebas Tahun 2020. Hasil uji statistik diketahui bahwa p value 0.021 menunjukan bahwa terdapat hubungan keterpaparan media dengan Pengetahuan Siswa Siswi SMP IT Nur Hikmah kelas VIII dan IX Tentang Dampak Pergaulan Bebas Tahun 2020.
KEBIASAAN SARAPAN SEBAGAI DETERMINAN PRESTASI BELAJAR SISWA MTs NURUL FALAH JUAI KABUPATEN BALANGAN
Authors: Ernadi Erwin , Ilmi M. Bahrul
Published: February 2022

Sarapan adalah menu makanan pertama yang di konsumsi seseorang. Tanpa sarapan seseorang akan mengalami hipoglikemia atau kadar glukosa dibawah normal. Hipoglikemia mengakibatkan tubuh gemetaran, pusing dan sakit berkonsentrasi. Penelitian ini bertujuan untuk mengetahui kebiasaan sarapan sebagai determinan prestasi belajar siswa SMPN Sederajat di Kecamatan Juai Kabupaten Balangan. Jenis penelitian ini yaitu analitik dengan pendekatan cross sectional study. Yang menjadi sampel penelitian yaitu semua siswa terdiri dari laki-laki dan perempuan yang terdapat pada sekolah MTs Nurul Falah di Kecamatan Juai Kabupaten Balangan. Instrumen yang digunakam dalam penelitian ini adalah berupa lembar pertanyaan (kuesioner) & wawancara yang berisi daftar pertanyaan tentang kebiasaan sarapan sebagai determinan prestasi belajar siswa. Data kemudian diolah dan dianalisis dengan uji statistika Chi Square untuk menguji hipotesis penelitian. Berdasarkan hasil penelitian, ada hubungan antara kebiasaan sarapan dengan perstasi belajar. Diharapkan adanya peningkatan informasi tentang pola hidup sehat baik kepada instansi pendidikan maupun orangtua siswa.
HUBUNGAN KADAR GULA DARAH PENDERITA DIABETES MELLITUS TIPE 2 DENGAN KASUS KEGOYANGAN GIGI PADA PUSKESMAS PENGARON KABUPATEN BANJAR
Authors: Fansurna Anderi , Utami Naning Kisworo
Published: February 2022

Masalah kesehatan salah satunya kesehatan rongga mulut termasuk kesehatan gigi. Gigi dan mulut dapat mengalami kelainan akibat suatu penyakit lokal maupun sistemik, antara lain penyakit sistemik adalah diabetes mellitus, akumulasi plak dan modulasi dari respon host melalui efek dari diabetes dapat berubah menjadi severe dan terjadi kerusakan periodontal yang luas termasuk gigi goyang. Tujuan penelitian untuk mengetahui hubungan kadar gula darah penderita diabetes mellitus tipe 2 dengan kasus kegoyangan gigi. Jenis penelitian bersifat analitik observasional dengan rancangan cross sectional, populasi penelitian 359 orang, sampel 36 orang diambil dengan metode purposive sampling. Hasil penelitian dengan uji korelasi menggunakan produk moment pearson diketahui kriteria pengujian adalah Ho=Sig>alpha dan Ha=Sig0,05) dapat diambil kesimpulan tidak ada hubungan kadar gula darah penderita diabetes mellitus tipe 2 dengan kasus kegoyangan gigi dengan menggunakan kriteria Periodontal Disease Indeks (PDI), karena Sig lebih besar dari alpha. Perlu perhatian dari tenaga kesehatan gigi tentang pentingnya menjaga kesehatan gigi dan mulut penderita diabetes mellitus, pemeriksaan dan pengontrolan kadar gula darah serta kesehatan gigi secara berkala termasuk pembersihan karang gigi, pemeliharaan bagi pemakai gigi tiruan sehingga faktor lokal yang menjadi penyebab terjadinya infeksi pada gusi dan efek lanjut penyebab kegoyangan gigi dapat dihindari.
ANALISIS PENDAPATAN USAHATANI KANGKUNG (Ipomoea reptans poir) JALAN SUKAMARA KELURAHAN LANDASAN ULIN UTARA KECAMATAN LIANG ANGGANG KOTA BANJARBARU PROVINSI KALIMANTAN SELATAN
Authors: Wasdiyanta Wasdiyanta
Published: February 2022

This research takes the title of the analysis of kangkung farming income (ipomeae reptans poir)The observation was carried out on Sukamara Street in March 2020 with a simple random sampling method.This research was conducted by survey method with participatory observation techniques, the purpose of this research is to find out how to cultivate water spinach farming and how much is the total cost and income in one growing season the results of the study obtained a total cost of Rp. 34,570,305, -, receipt of Rp. 67,554,000, - so the income is Rp. 32,983,685