bluuebunny/crossref_metadata_2025 huggingface dataset:
The Use of MM/QM Calculations of 13C Chemical Shifts in the Analysis of Edaravone Tautomers
Authors: Abraham Raymond J. , Cooper M. Ashley , Aghamohammadi Amin , Afarinkia Kamyar , Liu Xiangli
Published: August 2022

The13C NMR chemical shifts of the three Edaravone tautomers (keto, enol, and amine) were calculated using a combined molecular mechanics (Pcmod 9.1/MMFF94) and ab initio (GIAO (B3LYP/DFT, 6–31 + G(d)) model. This method gave such good agreement with experiment that the assignment of the complex spectrum of Edaravone in solution, which is a mixture of the three tautomers could be made. This has been attempted previously by various methods with diverse results. In CDCl3solution, the observed spectra show only one form, the keto tautomer, and this is also the case with acetonitrile solvent. Acetone solvent reacts with Edavarone in the NMR tube. In the other solvents studied, methanol, pyridine, DMSO, trifluoroethanol (TFE), there is a mixture of the tautomers with populations which vary with the solvent. The application of the shift predictions allows the assignment of the13C spectra to the three tautomers and from this the proportions of the tautomers in the solution. The results at times differ significantly from previous studies, and this is discussed.
New Discrete Formulation for Reduced Population Balance Equation: An Illustration to Crystallization
Authors: Singh Mehakpreet , Walker Gavin
Published: August 2022

In this paper, we focus on providing a discrete formulation for a reduced aggregation population balance equation. The new formulation is simpler, easier to code, and adaptable to any type of grid. The presented method is extended to address a mixed-suspension mixed-product removal (MSMPR) system where aggregation and nucleation are the primary mechanisms that affect particle characteristics (or distributions). The performance of the proposed formulation is checked and verified against the cell average technique using both gelling and non gelling kernels. The testing is carried out on two benchmarking applications, namely batch and MSMPR systems. The new technique is shown to be computationally less expensive (approximately 40%) and predict numerical results with higher precision even on a coarser grid. Even with a revised grid, the new approach tends to outperform the cell average technique while requiring less computational effort. Thus the new approach can be easily adapted to model the crystallization process arising in pharmaceutical sciences and chemical engineering.
No Grounds for Fictionalism
Authors: Knowles Robert
Published: August 2022

I argue that fictionalism about grounding is unmotivated, focusing on Naomi Thompson’s (2022) recent proposal on which the utility of the grounding fiction lies in its facilitating communication about what metaphysically explains what. I show that, despite its apparent dialectical kinship with other metaphysical debates in which fictionalism has a healthy tradition, the grounding debate is different in two key respects. Firstly, grounding talk is not indispensable, nor even particularly convenient as a means of communicating about metaphysical explanation. This undermines the revolutionary proposal. Secondly, talk of grounding primarily occurs within metaphysics, which means the usual options for motivating a non-literal interpretation are ineffective. This undermines the hermeneutic proposal.
Exploring food security as a multidimensional topic: twenty years of scientific publications and recent developments
Authors: Righettini Maria Stella , Bordin Elisa
Published: August 2022

The scientific literature dealing with food security is vast and fragmented, making it difficult to understand the state of the art and potential development of scientific research on a central theme within sustainable development.

The current article, starting from some milestone publications during the 1980s and 1990s about food poverty and good nutrition programmes, sets out the quantitative and qualitative aspects of a vast scientific production that could generate future food security research. It offers an overview of the topics that characterize the theoretical and empirical dimensions of food security, maps the state of the art, and highlights trends in publications’ ascending and descending themes. To this end the paper applies quantitative/qualitative methods to analyse more than 20,000 scientific articles published in Scopus between 2000 and 2020.

Evidence suggests the need to find more robust links between micro studies on food safety and nutrition poverty and macro changes in food security, such as the impact of climate change on agricultural production and global food crises. However, the potential inherent in the extensive and multidisciplinary research on food safety encounters limitations, particularly the difficulty of theoretically and empirically connecting the global and regional dimensions of change (crisis) with meso (policy) and micro (individual behaviour) dimensions.
Improving quality of the scanner CPI: proposition of new multilateral methods
Authors: Białek Jacek
Published: August 2022

Scanner data can be obtained from a wide variety of retailers (supermarkets, home electronics, Internet shops, etc.) and provide information at the level of the barcode, i.e. the Global Trade Item Number or its European version: European Article Number. One of advantages of using scanner data in the Consumer Price Index measurement is the fact that they contain complete transaction information, i.e. prices and quantities for every sold item. One of new challenges connected with scanner data is the choice of the index formula which should be able to reduce the chain drift bias and the substitution bias. Multilateral index methods seem to be the best choice in the case of dynamic scanner data sets. These indices work on a whole time window and are transitive, which is a key property in eliminating the chain drift effect. Following the so-called identity test, however, one may expect that even when only prices return to their original values, the index becomes one. Unfortunately, the commonly used multilateral indices (GEKS, CCDI, GK, TPD, TDH) do not meet the identity test. The paper discusses the proposal of two multilateral indices, the idea of which resembles the GEKS index, but which meet the identity test and most of other tests. In an empirical study, these indices are compared, inter alia, with the SPQ index, which is relatively new and also meets the identity test. Analytical considerations as well as empirical study confirm the high usefulness of the proposed indices.
How family firms use governance mechanisms to mitigate the risks of ecosystems: a case study from healthcare
Authors: Cobben Dieudonnee , Neessen Petra C. M. , Rus Diana , Roijakkers Nadine
Published: August 2022

This study aims to increase our understanding of how family firms, acting as ecosystem orchestrators, mitigate perceived relational and performance risk in ecosystems via the use of governance mechanisms. We use the ecosystem governance literature to understand whether family firms’ characteristics lead to a unique governance approach in an ecosystem setting. Our findings and theoretical implications are threefold; (1) formal and informal governance mechanisms act as complements to mitigate relational and performance risks; (2) the choice of governance mechanisms differs for relational and performance risk; (3) changes in perceived risk over time result in shifts in the relative dominance of formal/informal governance mechanisms.
Knowledge of art vs. artistic knowledge. II. The GAKhN “Encyclopedia of Artistic Terminology”
Authors: Plotnikov Nikolaj
Published: August 2022

In this second article, I look at the history of the creation of the “Encyclopedia of Artistic Terminology” within the State Academy of the Artistic Sciences. I analyze various versions of the encyclopedia’s conception proposed by Wassily Kandinsky and Gustav Shpet and also at the theoretical bases for these conceptions. I then show how the work on the Encyclopedia was connected with the institutional transformations in the Academy. A key factor in the work on the Encyclopedia was the extensive discussions of the fundamental aesthetic terms that took place in the Philosophy Department and in sections of GAKhN. As the dynamics of the discussions also determined changes in the conception of the Encyclopedia, so work on it shifted more and more from a project for creating a new system of aesthetic concepts to a reconstruction of the “history of concepts.” Such a transition marked the main vector of the development of European discussions about aesthetic concepts—from the creation of systems of aesthetic categories to historical reflection on the semantic transformations of categories. In conclusion, I investigate the cessation of work on the Encyclopedia in 1929 in response to the outside ideological pressure and the elimination of the possibility for autonomous theoretical work within the walls of the Academy.
Spotted fever group Rickettsia, Anaplasma and Coxiella-like endosymbiont in Haemaphysalis ticks from mammals in Thailand
Authors: Hirunkanokpun Supanee , Ahantarig Arunee , Baimai Visut , Pramual Pairot , Rakthong Pakavadee , Trinachartvanit Wachareeporn
Published: August 2022

Ticks are ectoparasites of vertebrates and vectors of various pathogenic microorganisms. In this study, the presence of bacteria and protozoa was evaluated by PCR and DNA sequencing in 233 mammal ticks collected from 8 provinces in Thailand. Sequence and phylogenetic analyses of partial rickettsial ompA, ompB, sca4 and partial Coxiella 16S rRNA, GroEL, rpoB genes clearly revealed, for the first time, a co-infection of SFG Rickettsia belonging to R. massiliae subgroup and Coxiella-like endosymbiont (CLE), Cox-hein, in a male of Haemaphysalis heinrichi tick infesting Burmese ferret-badger in Loei province. Moreover, a male of H. hystricis tick infesting the same host was infected with another CLE, Cox-hys. Based on the 16S rRNA gene sequence, Anaplasma sp., closely related to Anaplasma bovis was also detected in a male of H. heinrichi infesting the same Burmese ferret-badger. In addition, the third CLE, Cox-asia, found in H. asiatica collected from Asian palm civet in Chiang Rai province, was different from both Cox-hein and Cox-hys. This study provided important data and broadened our knowledge on tick-borne pathogens and endosymbionts in Thailand and Southeast Asia.
MRI of odontogenic maxillofacial infections: diagnostic accuracy and reliability
Authors: Heikkinen Jaakko , Jokihaka Viljami , Nurminen Janne , Jussila Ville , Velhonoja Jarno , Irjala Heikki , Soukka Tero , Happonen Tatu , Järnstedt Jorma , Nyman Mikko , Mattila Kimmo , Hirvonen Jussi
Published: August 2022

Objectives

To determine the diagnostic accuracy of emergency magnetic resonance imaging (MRI) in odontogenic maxillofacial infections, the clinical and surgical significance of MRI findings, and whether MRI can identify the tooth responsible for the infection.

Methods

A retrospective cohort study reviewed 106 emergency neck MRI scans of patients with neck infections of odontogenic origin. The diagnostic accuracy of MRI in identifying abscesses was studied relative to surgical findings. Correlations were analyzed between various MRI findings and clinical results and outcomes, such as the surgical approach (intraoral vs. extraoral). The ability of MRI findings to predict the causative tooth was assessed in a blinded multi-reader setting.

Results

Of the 106 patients with odontogenic infections, 77 (73%) had one or more abscesses. Imaging showed a sensitivity, specificity, and accuracy of 0.95, 0.84, and 0.92, respectively, for MRI diagnosis of an odontogenic abscess. Among the imaging findings, mediastinal edema was the strongest predictor of extraoral surgery. MRI showed bone marrow edema in the majority of patients, and multi-reader assessment showed good reliability. MRI was also able to predict the causative tooth accurately.

Conclusions

Emergency neck MRI can accurately detect odontogenic abscesses and reliably point to the causative tooth. These results can increase the utility and reliance on emergency MRI in clinical decision-making.
Evaluation des wissenschaftsbasierten kommunalen Präventionssystems Communities That Care: Studiendesign und Baseline-Äquivalenz intermediärer Outcomes
Authors: Röding Dominik , Reder Maren , Soellner Renate , Birgel Vera , Stolz Maike , Groeger-Roth Frederick , Walter Ulla
Published: August 2022

Hintergrund

Communities That Care (CTC) ist ein Ansatz zur Übertragung präventionswissenschaftlicher Grundlagen in die kommunale Präventionspraxis. Mittels Schulungen und Tools unterstützt CTC Kommunen beim Aufbau lokaler Netzwerke zur Förderung der psychosozialen Gesundheit von Kindern und Jugendlichen. Bürgerbeteiligung, intersektorale Zusammenarbeit, wissenschaftsbasierte Prävention, Monitoring und Qualitätsentwicklung sind zentrale Elemente von CTC. Ergebnisse aus den USA legen nahe, dass die Wirkung von CTC auf Gesundheitsverhalten durch fünf intermediäre Outcomes vermittelt wird. Der Beitrag stellt erste Ergebnisse der Studie „Effektivität des kommunalen Präventionssystems Communities That Care“ (CTC-EFF) vor, die die Effektivität von CTC für Deutschland untersucht.

Daten und Methoden

Die CTC-EFF-Studie ist eine quasiexperimentelle Studie. Einbezogen sind 21 Kommunen, die CTC einführen (IK) und 21 a priori gematchte Vergleichskommunen (VK), die diesen hinsichtlich demographischen, wirtschaftlichen und kriminalstatistischen Merkmalen ähneln. 2021 wurden Befragungen mit 192 kommunalen Schlüsselpersonen (u. a. Amts- und Einrichtungsleitungen) durchgeführt. Bivariat wurde untersucht, ob sich die Befragten von IK und VK hinsichtlich acht soziodemographischer Merkmale, ihrer Einschätzungen zu Präventionszusammenarbeit, intersektoraler Kooperation, finanzieller Unterstützung, Rückhalt in der Bevölkerung sowie Übernahme wissenschaftsbasierter Prävention unterscheiden.

Ergebnisse

Die Befragten aus IK und VK unterscheiden sich in den soziodemographischen Merkmalen mit Ausnahme der Hochschulzugangsberechtigung (IK: 86 % vs. VK: 96 %) nicht signifikant. Auch werden Präventionszusammenarbeit, intersektorale Kooperation, finanzielle Unterstützung und Rückhalt in der Bevölkerung von den Befragten nicht unterschiedlich eingeschätzt. Eine Ausnahme bildet die Übernahme wissenschaftsbasierter Prävention.

Schlussfolgerung

Das Matching führte weitgehend zu Baseline-Äquivalenz in den untersuchten Merkmalen. Der kleine Vorsprung der IK gegenüber den VK in der Übernahme wissenschaftsbasierter Prävention ist plausibel, da die IK vor der Erhebung bereits erste Schulungen und Implementationsschritte vollzogen hatten.
Current status and challenges of percutaneous vertebroplasty (PVP)
Authors: Noguchi Tomoyuki , Yamashita Koji , Kamei Ryotaro , Maehara Junki
Published: August 2022

A narrative review regarding percutaneous vertebroplasty (PVP) for osteoporotic vertebral fracture (OVF) is provided herein, addressing the epidemic of OVF in Japan, the latest response to the criticism of PVP for OVFs, the indications and potential risks of PVP for OVFs, and a future perspective for PVP. Each year in Japan, approximately 32,000 patients aged 55 years or older suffer from chronic low back pain for several months to several years due to a compression fracture. PVP is one of the surgical treatments for an OVF, and it is less invasive compared to the traditional open surgery. PVP is suitable for OVF patients who have difficulty walking as assessed by the modified Yokoyama’s activities of daily living (ADL) scoring system, and for patients with Kummell's disease diagnosed by CT and MRI examinations. Serious adverse events related to PVP occur in 1.1–3.3% of the cases, but direct deaths from PVP are extremely rare at less than 1%. Recent studies demonstrated that OVF patients treated with PVP are less likely to die after the treatment than non-surgically treated patients, which conflicts with the Cochran reviews’ conclusion not supporting PVP for OVFs. Novel robotic systems and procedure-support devices are being developed, providing a next step toward fully automated PVP procedures.
Characteristics of fatal insulin overdoses
Authors: Stephenson Lilli , van den Heuvel Corinna , Humphries Melissa , Byard Roger W.
Published: August 2022

This study was undertaken to review fatal cases of insulin overdose in South Australia (SA) over a 20-year period to assess rates and characteristics of insulin-related deaths among insulin-dependent diabetics and non-diabetics for all manners of death. Records from the National Coronial Information System (NCIS) and Forensic Science SA (FSSA) were searched for all cases of fatal insulin overdose in South Australia (SA) between 2000 and 2019. Collected variables included age, sex, cause of death, scene findings, manner of death, decedent medical and personal histories, biochemistry, toxicology, histopathology, and autopsy findings. Statistical analyses were performed using R (version 4.1.2). Forty cases of insulin overdose were identified in SA between 2000 and 2019. Twenty-nine cases (72.5%) were suicides, with the remaining cases classified as accidental or undetermined intent. Thirteen of the 22 insulin-dependent diabetics (59%) had a history of depression, 10 of whom had previously demonstrated suicidal ideation. The current study has shown that suicides using insulin among insulin-dependent diabetics are equally as prevalent, if not more so than fatal accidental insulin overdoses. This can largely be attributed to insulin-dependent diabetic access to a potentially lethal substance. Suicide prevention strategies should focus on insulin-dependent diabetics with a history of depression, particularly for those with access to rapid-acting insulin.
Sorafenib maintenance after hematopoietic stem cell transplantation improves outcome of FLT3–ITD-mutated acute myeloid leukemia
Authors: Aydin Semra , Passera Roberto , Scaldaferri Matilde , Dellacasa Chiara Maria , Poggiu Marco , Cattel Francesco , Zallio Francesco , Brunello Lucia , Giaccone Luisa , Dogliotti Irene , Busca Alessandro
Published: August 2022

In a retrospective analysis, 21 acute myeloid leukemia patients receiving single-agent sorafenib maintenance therapy in complete remission (CR) after hematopoietic stem cell transplantation (HSCT) were compared with a control group of 22 patients without maintenance. Sorafenib was initiated a median of 3 months (IQR: 2.3–3.5) after allogeneic HSCT with a median daily dosage of 400 mg (range: 200–800) orally, and lasted a median of 11.3 months (IQR: 3.3–24.4). No significant increase in graft versus host disease or toxicity was observed. Adverse events were reversible with dose adjustment or temporary discontinuation in 19/19 cases. With a median follow-up of 34.7 months (IQR: 16.9–79.5), sorafenib maintenance significantly improved cumulative incidence of relapse (p = 0.028) as well as overall survival (OS) (p = 0.016), especially in patients undergoing allogeneic HSCT in CR1 (p < 0.001). In conclusion, sorafenib maintenance after allogeneic HSCT is safe and may improve cumulative incidence of relapse and OS in FLT3–ITD-mutated AML.
MXene-Based Photocatalysts and Electrocatalysts for CO2 Conversion to Chemicals
Authors: Amrillah Tahta , Supandi Abdul Rohman , Puspasari Vinda , Hermawan Angga , Seh Zhi Wei
Published: August 2022

The interest in CO2 conversion to value-added chemicals and fuels has increased in recent years as part of strategic efforts to mitigate and use the excessive CO2 concentration in the atmosphere. Much attention has been given to developing two-dimensional catalytic materials with high-efficiency CO2 adsorption capability and conversion yield. While several candidates are being investigated, MXenes stand out as one of the most promising catalysts and co-catalysts for CO2 reduction, given their excellent surface functionalities, unique layered structures, high surface areas, rich active sites, and high chemical stability. This review aims to highlight research progress and recent developments in the application of MXene-based catalysts for CO2 conversion to value-added chemicals, paying special attention to photoreduction and electroreduction. Furthermore, the underlying photocatalytic and electrocatalytic CO2 conversion mechanisms are discussed. Finally, we provide an outlook for future research in this field, including photoelectrocatalysis and photothermal CO2 reduction.
Reappraisal of 75 Years of Exploration for Atomic Minerals in India and the Way Forward
Authors: Sinha D. K.
Published: August 2022

In India, Atomic Minerals Directorate for Exploration and Research (AMD), the oldest unit under the Department of Atomic Energy (DAE) is mandated with the exploration and augmentation of atomic mineral(s) resources of the country to support the Nuclear Power Programme (NPP) of India.

AMD, till date have established four (04) generations of uranium metallogeny in India, distributed in 46 deposits and several other occurrences, major share of which are contributed by the globally unique, stratabound carbonate hosted, syn-diagenetic Tummalapalle Group of deposit (~59%), metamorphite type deposits along the Singhbhum Shear Zone (~21%), unconformity related deposits in northern part of Cuddapah Basin (~5%) and sandstone type deposits in Cretaceous Mahadek Basin (~6%). Besides these, metasomatite type deposits along the North Delhi Fold Belt (4%) and granite related-structurally controlled, high grade deposits in Bhima Basin (2%) along with some small hydrothermal/metamorphite/migmatite type deposits in Aravalli, Kotri-Dongargarh, Higher Himalaya belts and Chhotanagpur Granite Gneiss Complex contribute to the national inventory which stands at 3,76,000 tonne uranium oxide. AMD have stockpiled substantial quantities of Nb-Ta, Be and Li minerals needed for the NPP of India from prospective pegmatite belts in the country. AMD have established immense potential for REE mineralization in carbonatite complexes of Ambadungar in Gujarat and per-alkaline granite-rhyolite of Siwana Ring Complex, Barmer district, Rajasthan. Exploration along the coastal and riverine placers of the country has established 130 heavy mineral placer deposits with substantial thorium and REE resources.

The progressive advancements by AMD through adaptation of integrated multidisciplinary exploration techniques coupled with major thrust in airborne/ground geophysics and expansion of state-of-the-art analytical facilities have facilitated systematic planning for future augmentation of atomic mineral(s) resources. Exploration inputs are envisaged to be intensified in the brownfield target areas for resource augmentation while R&D and phase-wise exploration inputs will be focused for developing the identified greenfield areas following a planned roadmap to ensure selfsufficiency in atomic mineral resources for sustained growth of the NPP to reach the target of net zero carbon emissions by 2070.
Genesis of Magmatic Albitite Related Hydrothermal Uranium Mineralisation in Geratiyon-ki-Dhani, Sikar District, Rajasthan: Evidences from Fluid Inclusion Studies
Authors: Saxena Anubhooti , Mathew Shijo , Kumar Monu , Bisht B.S. , Sinha D.K.
Published: August 2022

Geratiyon-ki-Dhani (GKD) area is located in Khetri sub-basin of North Delhi Fold Belt and exposes metasediments of Ajabgarh Group. The Ajabgarh Group comprises quartz-biotite schist which is intruded by albitite and granite. The primary uranium phases viz. davidite and brannerite occurring with calcite and /or quartz veins are common in albitite. Quartz and calcite from mineralised albitite have been selected for characterization of the ore-forming fluid, which makes a promising uranium deposit.

Fluid inclusion petrography indicated presence of three (03) types of fluid inclusions (FIs) based on phases present at room temperature and mode of occurrence; polyphase (type 1a & 1b) and biphase (type 2) inclusions. Type 1a FIs are primary in nature and are composed of vapour bubble, salt crystals with <50% liquid phase and are irregular or negative crystal in shape varying in size between 12–23μm and occasionally contain hematite grain. The type 1a inclusions homogenised mostly by dissolution of salt crystal between 243-382°C (mode=340°C, n=30) corresponding to salinity of 34.32–46.13 wt% NaCl-eq (mode=42wt% NaCl-eq, n=30). Type 1b FIs have vapour bubble, salt crystal with > 50% liquid phase, occur as trans-granular trails and in clusters, having irregular shapes with size varying from <5–12μm. The inclusions homogenised by disappearance of salt crystals at 209 to 294°C (mode= 280°C, n=35) corresponding to salinity range from 29.03–38.59 wt% NaCl-eq (mode=36wt% NaCl-eq, n=35).

A wide range of overlap is noted in salinity (34.32–38.59 wt% NaCl-eq) and homogenization temperature (243 – 294°C), histograms of type 1a & 1b inclusions suggest them to be part of a common fluid activity. Polyphase inclusions show simple cooling and follow halite saturation curve in salinity-temperature diagram. Biphase inclusions are invariably associated with type 1b and also show a cooling trend. On the basis of fluid characteristics, it is concluded that magmatic albitite has provided single mineralising solution resulting in davidite enriched mineralisation. The gradual cooling of high temperature (243- 382°C), high saline (34.32– 46.13 wt% NaC-leq) hydrothermal fluids has ensued U-mineralisation in GKD. The evidences presented here are significant as magmatic albitite hosted mineralisation is found for the first time in North Delhi Fold Belt of Khetri sub-basin of northwest India. It has opened a new concept for exploration which will help more resource addition.
Development and Scale-up of Chemical Process for Conversion of Impure Sodium Diuranate to Uranium Peroxide
Authors: Rao K. Anand , Patel A. B. , Gujral Mahek , Karan Ram , Kumar M. Ajay , Serajuddin Md , Sreenivas T.
Published: August 2022

Uranium mills following the sulfuric acid leaching route produce Uranium Peroxide (UP) as uranium ore concentrate (yellow cake), which is then refined to produce nuclear grade uranium products. Whereas the mills processing ores by alkaline leaching route generate Sodium Diuranate (SDU) as yellow cake, which commonly contains impurities viz. Zr, SiO2, Mo, Organic Carbon (OC). These impurities form muck, interfacial crud and acid insolubles during digestion and solvent extraction (SX) stages in refining process. Hence, SDU needs to be pre-treated before processing in the uranium refinery. India has substantial U reserves (>50%) hosted in carbonate minerals matrix which obviously need alkaline processing for extraction of U. In the present study, the origin of impurities in a SDU produced in an Indian Uranium mill was traced back to the mineralogical composition of the ore, chemical reactivity of minerals to the reagents,and build-up of impurities in process streams due to existence of multiple recycle streams in the milling process flowsheet. A process scheme has been developed for converting SDU into highly pure Heat Treated Uranium Peroxide (HTUP). The scheme involves digestion of SDU in sulfuric acid medium followed by separation of insolubles from the liquor which is later subjected to pH controlled U-peroxide precipitation process. The U-peroxide formed was heat treated to drive-off active oxygen and water of crystallization. A HTUP product assaying about 91% U3O8 was produced from an impure SDU assaying 74% U3O8. Process has been demonstrated at large scale (about 100 kg/batch) and engineering data and scale up parameters have been generated.
Public engagement and argumentation in science
Authors: Ivani Silvia , Dutilh Novaes Catarina
Published: August 2022

Public engagement is one of the fundamental pillars of the European programme for research and innovationHorizon 2020. The programme encourages engagement that not only fosters science education and dissemination, but also promotes two-way dialogues between scientists and the public at various stages of research. Establishing such dialogues between different groups of societal actors is seen as crucial in order to attain epistemic as well as social desiderata at the intersection between science and society. However, whether these dialogues can actually help attaining these desiderata is far from obvious. This paper discusses some of the costs, risks, and benefits of dialogical public engagement practices, and proposes a strategy to analyse these argumentative practices based on a three-tiered model of epistemic exchange. As a case study, we discuss the phenomenon of vaccine hesitancy, arguably a result of suboptimal public engagement, and show how the proposed model can shed new light on the problem.
A comparison of strategies used and considered to mitigate droughts in California
Authors: Keavney Elizabeth
Published: August 2022

While California has ideal weather for many activities, beaches, and mountains, the water shortage in the state has caused challenges for its growing population. The state has implemented some water saving measures but must do more to meet its needs as its population continues to increase. This paper explores what has been done and what might be done to seek more sources of water. Existing literature tends to examine individual options, instead of performing a broader comparison. This study uses comparative analysis to evaluate multiple approaches to mitigating the effects of drought in California, comparing cost information, technical maturity, and less easily quantified advantages and disadvantages. The study found that conservation, wastewater recycling, water transfer, and similar options have been used successfully in California in the past and should continue to be used. Because all those approaches except wastewater recycling are reaching their limits, the most feasible method to mitigate future droughts in California is increased use of wastewater recycling. However, it faces some emotional and political obstacles to its widespread use.
Ultrasonic-assisted synthesis of Fe3O4 nanoparticles-loaded sawdust carbon for malachite green removal from aquatic solutions
Authors: Bonyadi Ziaeddin , Khatibi Fatemeh Sadat , Alipour Fatemeh
Published: August 2022

MG, an organic compound composed of triphenyl methane, is often widely used in various industries, especially in the food, pharmaceutical and textile industries. This study emphasizes the green synthesis of novel magnetic iron oxide nanoparticles-loaded sawdust carbon (Fe3O4/SC) and their effect on the removal of MG from the aqueous solution. To obtain the optimum conditions of MG removal using the Box–Behnken model, the independent variables such as the initial MG concentration (10–100 mg/L), pH (3–9), reaction time (10–60 min), and Fe3O4/SC nanocomposites dose (0.2–1 g/L) were experimented. According to the quadratic model, the highest removal rate (89.22%) was found at the pH of 8.62, the contact time of 59.86 min, the Fe3O4/SC ncs dose of 0.59 g /L and the MG level of 17.62 mg/L. The MG removal rate follows the pseudo-second-order model and the Langmuir model. The maximum absorption capacity for MG was 41.66 mg/g. These findings suggest that the Fe3O4/SC ncs has a significant potential for the MG adsorption from aqueous solution.
Effect of CO2 on the interfacial tension and swelling of crude oil during carbonated water flooding
Authors: Farahabadi Zahra Taghizadeh , Lashkarbolooki Mostafa
Published: August 2022

Since the influence of carbon dioxide (CO2) on the dynamic interfacial tension of crude oil and aqueous solutions at the elevated temperatures and pressures is an important issue, this investigation is aimed to measure the IFT of crude oil/water, CO2, and carbonated water. The measured values reveal that the IFTs of crude oil/CO2 are decreased through the first interval, while a gradual and continuous reduction in IFT is obtained at the second interval. Although both intercepts and slopes of the first interval lines are more than the second interval for all the studied temperatures, they show a similar trend as a function of temperature. The used vanishing IFT method measurement reveals that the minimum miscibility pressure (MMP), first contact miscibility pressure, and intersection point (where the slopes of the linear curves change) of two linear equations have a linear increasing trend as temperature changes. However, this trend was not observed for the aqueous solution saturated with CO2 (i.e., carbonated water) which can be related to the difference between liquid- and gas-phase behavior as well as the formation of carbonic acid in the carbonated water process. IFT values reduced from 18.6 mN/m (@ pH = 8) to 0.3 mN/m (@ pH = 14) with an increase in pH of the aqueous solution, while miscibility conditions can be obtained for CO2 cases at pressures higher than the MMP points. Considerably higher IFT values were measured in the presence of water and carbonated water in the range of 9.1–17.5 mN/m and 12.2–17.4 mN/m, respectively. The most important feature of the CW process can be the swelling factor of crude oil due to the fact that the oil swelling of up to 40% was achieved at elevated temperature (75 °C) and pressure (4500 psi) after only1600 s.
Leveraging collective action and environmental literacy to address complex sustainability challenges
Authors: Ardoin Nicole M. , Bowers Alison W. , Wheaton Mele
Published: August 2022

Developing and enhancing societal capacity to understand, debate elements of, and take actionable steps toward a sustainable future at a scale beyond the individual are critical when addressing sustainability challenges such as climate change, resource scarcity, biodiversity loss, and zoonotic disease. Although mounting evidence exists for how to facilitate individual action to address sustainability challenges, there is less understanding of how to foster collective action in this realm. To support research and practice promoting collective action to address sustainability issues, we define the term “collective environmental literacy” by delineating four key potent aspects: scale, dynamic processes, shared resources, and synergy. Building on existing collective constructs and thought, we highlight areas where researchers, practitioners, and policymakers can support individuals and communities as they come together to identify, develop, and implement solutions to wicked problems. We close by discussing limitations of this work and future directions in studying collective environmental literacy.
Continuing professional development challenges in a rural setting: A mixed-methods study
Authors: Campos-Zamora Melissa , Gilbert Hannah , Esparza-Perez Ramiro I. , Sanchez-Mendiola Melchor , Gardner Roxane , Richards Jeremy B. , Lumbreras-Marquez Mario I. , Dobiesz Valerie A.
Published: August 2022

Introduction Health professionals in rural settings encounter a wide range of medical conditions requiring broad knowledge for their clinical practice. This creates the need for ongoing continuing professional development (CPD). In this study, we explored the barriers that health professionals in a rural healthcare context faced participating in CPD activities and their preferences regarding educational strategies to overcome these challenges.

Methods This mixed-methods (exploratory sequential) study in a community hospital in rural Mexico includes 22 interviews, 3 focus groups, 40 observational hours, and a questionnaire of healthcare staff.

Results Despite low engagement with CPD activities (67% not motivated), all participants expressed interest and acknowledged the importance of learning for their practice. Barriers to participating include a disparity between strategies used (lecture-based) and their desire for practical learning, institutional barriers (poor leadership engagement, procedural flaws, and lack of resources), and collaboration barriers (adverse interprofessional education environment, ineffective teamwork, and poor communication). Additional barriers identified were inconvenient scheduling of sessions (75%), inadequate classrooms (65%), high workload (60%), ineffective speakers (60%), and boring sessions (55%). Participants’ preferred learning strategies highlighted activities relevant to their daily clinical activities (practical workshops, simulations, and case analysis). The questionnaire had an 18% response rate.

Discussion The barriers to CPD in this rural setting are multifactorial and diverse. A strong interest to engage in context-specific active learning strategies highlighted the need for leadership to prioritize interprofessional education, teamwork, and communication to enhance CPD and patient care. Thes
Scholarly knowledge graphs through structuring scholarly communication: a review
Authors: Verma Shilpa , Bhatia Rajesh , Harit Sandeep , Batish Sanjay
Published: August 2022

The necessity for scholarly knowledge mining and management has grown significantly as academic literature and its linkages to authors produce enormously. Information extraction, ontology matching, and accessing academic components with relations have become more critical than ever. Therefore, with the advancement of scientific literature, scholarly knowledge graphs have become critical to various applications where semantics can impart meanings to concepts. The objective of study is to report a literature review regarding knowledge graph construction, refinement and utilization in scholarly domain. Based on scholarly literature, the study presents a complete assessment of current state-of-the-art techniques. We presented an analytical methodology to investigate the existing status ofscholarly knowledge graphs(SKG) by structuring scholarly communication. This review paper investigates the field of applying machine learning, rule-based learning, and natural language processing tools and approaches to construct SKG. It further presents the review of knowledge graph utilization and refinement to provide a view of current research efforts. In addition, we offer existing applications and challenges across the board in construction, refinement and utilization collectively. This research will help to identify frontier trends of SKG which will motivate future researchers to carry forward their work.
Reliability model of open source software considering fault introduction with generalized inflection S-shaped distribution
Authors: Wang Jinyong , Zhang Ce
Published: August 2022

Recently, the open source software (OSS) reliability has become one of hot issues. Owing to the uncertainty and complexity of OSS development, testing and debugging environments, OSS are completed dynamically. When detected faults are removed for OSS, they are likely to introduce new faults. Moreover, under the different OSS debugging environments, fault introduction will show different changes. For example, the fault introduction rate shows a decrease change, or increasing first and then decreasing change over time. Considering the complex and dynamic changes in fault introduction, an OSS reliability model that fault introduction obeys a generalized inflection S-shaped distribution is proposed in this paper. Experimental results indicate that the fitting and predictive performance of the proposed model is good. The established model in this paper can adapt the dynamical and complicated changes of fault introduction during OSS debugging. Moreover, the established model can accurately forecast the number of remaining faults in OSS, and assist developers to evaluate the actual OSS reliability.
Are we justified attributing a mistake in diagnosis to an AI diagnostic system?
Authors: Babushkina Dina
Published: August 2022

Responsible professional use of AI implies the readiness to respond to and address—in ethically appropriate manner—harm that may be associated with such use. This presupposes the ownership of mistakes. In this paper, I ask if a mistake in AI-enhanced decision making—such as AI-aided medical diagnosis—can be attributed to the AI system itself, and answer this question negatively. I will explore two options. If AI systems are merely tools, then we are never justified to attribute mistakes to them, because their failing does not meet rational constraints on being mistaken. If, for the sake of the argument, we assume that AI systems are not (mere) tools, then we are faced with certain challenges. The first is the burden to explain what this more-than-a-tool role of an AI system is, and to establish justificatory reasons for the AI system to be considered as such. The second is to prove that medical diagnosis can be reduced to the calculations by AI system without any significant loss to the purpose and quality of the diagnosis as a procedure. I will conclude that the problem of the ownership of mistakes in hybrid decision making necessitates new forms of epistemic responsibilities.
Minimal Generators from Positive and Negative Attributes: Analysing the Knowledge Space of a Mathematics Course
Authors: Ojeda-Hernández Manuel , Pérez-Gámez Francisco , López-Rodríguez Domingo , Madrid Nicolás , Mora Ángel
Published: August 2022

Formal concept analysis is a data analysis framework based on lattice theory. In this paper, we analyse the use, inside this framework, of positive and negative (mixed) attributes of a dataset, which has proved to represent more information on the use of just positive attributes. From a theoretical point of view, in this paper we show the structure and the relationships between minimal generators of the simple and mixed concept lattices. From a practical point of view, the obtained theoretical results allow us to ensure a greater granularity in the retrieved information. Furthermore, due to the relationship between FCA and Knowledge Space theory, on a practical level, we analyse the marks of a Mathematics course to establish the knowledge structure of the course and determine the key items providing new relevant information that is not evident without the use of the proposed tools.
Diapycnal diffusivities in Kelvin–Helmholtz engendered turbulent mixing: the diffusive–convection regime in the Arctic Ocean
Authors: Ma Yuchen , Peltier W.R.
Published: August 2022

Recent progress in the direct measurement of turbulent dissipation in the Arctic Ocean has highlighted the need for an improved parametrization of the turbulent diapycnal diffusivities of heat and salt that is suitable for application in the turbulent environment characteristic of this polar region. In support of this goal we describe herein a series of direct numerical simulations of the turbulence generated in the process of growth and breaking of Kelvin–Helmholtz billows. These simulations provide the data sets needed to serve as basis for a study of the stratified turbulent mixing processes that are expected to exist in the Arctic Ocean environment. The mixing properties of the turbulence are studied using a previously formulated procedure in which the temperature and salinity fields are sorted separately in order to enable the separation of irreversible Arctic mixing from reversible stirring processes and thus the definition of turbulent diffusivities for both heat and salt that depend solely upon irreversible mixing. These analyses allow us to demonstrate that the irreversible diapycnal diffusivities for heat and salt are both solely dependent on the buoyancy Reynolds number in the Arctic Ocean environment. These are found to be in close agreement with the functional forms inferred for these turbulent diffusivities in the previous work of Bouffard & Boegman (Dyn. Atmos. Oceans, vol. 61, 2013, pp. 14–34). Based on a detailed comparison of our simulation data with this previous empirical work, we propose an algorithm that can be used for inferring the diapycnal diffusivities from turbulent dissipation measurements in the Arctic Ocean.
Integrative structural modelling and visualisation of a cellular organelle
Authors: Autin Ludovic , Barbaro Brett A. , Jewett Andrew I. , Ekman Axel , Verma Shruti , Olson Arthur J. , Goodsell David S.
Published: August 2022

Models of insulin secretory vesicles from pancreatic beta cells have been created using the cellPACK suite of tools to research, curate, construct and visualise the current state of knowledge. The model integrates experimental information from proteomics, structural biology, cryoelectron microscopy and X-ray tomography, and is used to generate models of mature and immature vesicles. A new method was developed to generate a confidence score that reconciles inconsistencies between three available proteomes using expert annotations of cellular localisation. The models are used to simulate soft X-ray tomograms, allowing quantification of features that are observed in experimental tomograms, and in turn, allowing interpretation of X-ray tomograms at the molecular level.
Quasilinear theory for inhomogeneous plasma
Authors: Dodin I.Y.
Published: August 2022

This paper presents quasilinear theory (QLT) for a classical plasma interacting with inhomogeneous turbulence. The particle Hamiltonian is kept general; for example, relativistic, electromagnetic and gravitational effects are subsumed. A Fokker–Planck equation for the dressed ‘oscillation-centre’ distribution is derived from the Klimontovich equation and captures quasilinear diffusion, interaction with the background fields and ponderomotive effects simultaneously. The local diffusion coefficient is manifestly positive-semidefinite. Waves are allowed to be off-shell (i.e. not constrained by a dispersion relation), and a collision integral of the Balescu–Lenard type emerges in a form that is not restricted to any particular Hamiltonian. This operator conserves particles, momentum and energy, and it also satisfies the$\smash {H}$-theorem, as usual. As a spin-off, a general expression for the spectrum of microscopic fluctuations is derived. For on-shell waves, which satisfy a quasilinear wave-kinetic equation, the theory conserves the momentum and energy of the wave–plasma system. The action of non-resonant waves is also conserved, unlike in the standard version of QLT. Dewar's oscillation-centre QLT of electrostatic turbulence (Phys. Fluids, vol. 16, 1973, p. 1102) is proven formally as a particular case and given a concise formulation. Also discussed as examples are relativistic electromagnetic and gravitational interactions, and QLT for gravitational waves is proposed.
Hexabothriidae and Monocotylidae (Monogenoidea) from the gills of neonate hammerhead sharks (Sphyrnidae) Sphyrna gilberti, Sphyrna lewini and their hybrids from the western North Atlantic Ocean
Authors: Dalrymple Kaitlyn M. , de Buron Isaure , Hill-Spanik Kristina M. , Galloway Ashley S. , Barker Amanda , Portnoy David S. , Frazier Bryan S. , Boeger Walter A.
Published: August 2022

Neonates of hammerhead sharks (Sphyrnidae), Sphyrna lewini (Griffith and Smith, 1834), the sympatric cryptic species, Sphyrna gilberti Quattro et al., 2013, and their hybrids were captured in the western North Atlantic, along the coast of South Carolina, USA, between 2018 and 2019 and examined for gill monogenoids. Parasites were identified and redescribed from the gills of 79 neonates, and DNA sequences from partial fragments of the nuclear 28S ribosomal RNA (rDNA) and cytochrome c oxidase I mitochondrial DNA (COI) genes were generated to confirm species identifications. Three species of monogenoids from Hexabothriidae Price, 1942 and Monocotylidae Taschenberg, 1879 were determined and redescribed. Two species of Hexabothriidae, Erpocotyle microstoma (Brooks, 1934) and Erpocotyle sphyrnae (MacCallum, 1931), infecting both species of Sphyrna and hybrids; and 1 species of Monocotylidae, Loimosina wilsoni Manter, 1944, infecting only S. lewini and hybrids. Loimosina wilsoni 28S rDNA sequences matched those of Loimosina sp. from the southern coast of Brazil. Based on limited morphological analysis, Loimosina parawilsoni is likely a junior synonym of L. wilsoni. This is the first taxonomic study of monogenoids infecting S. gilberti and hybrids of S. gilberti and S. lewini.