bluuebunny/crossref_metadata_2025 huggingface dataset:
MISTAKES IN AUDIOVISUAL TRANSLATION: LINGUISTIC AND DIDACTIC ASPECTS
Authors: Лілія Яківна Терещенко
Published: April 2019

Introduction: Mistakes in audiovisual translation are generally caused by a wide rangeof lingual and extralingual factors. Translators’ unawareness of the nature of these factors hampersthe process of translation and results in misinterpretation of the message by the addressee.With fansubbing and crowdsourcing spreading worldwide, more and more experts are becomingconcerned with poor quality translations sprouting up before or simultaneously with theprofessionally interpreted or dubbed versions. Ukraine seems to have finally overcome the hardlycomprehensible voiceover of pirate DVDs (a sad legacy of the early 1990s). However, Ukrainianaudience is still struggling to understand some of the ‘quick fix’ versions of TV series, whichappear to be too numerous to be properly translated.Purpose: The objective of the article is to analyze typical mistakes that can occurin audiovisual translation and to outline the major causes of these mistakes.Methods: The research is based on randomly selected cases of inadequate voiceovertranslation of English fiction and documentary series into Ukrainian and Russian. The choiceof the films was prompted by the commentaries of Internet-users who indicated insufficientquality of translation of these films. Mistakes found were then analyzed from the point of viewof language and culture-specific constraints, interpreting mode constraints and personal constraintsthat might have affected the translator’s choice.Results: Apart from widely known linguistic phenomena of polysemy, homonymy,lexical lacunas, there are other stumbling blocks to faithful translation, such as lack of attentionto historical and cultural context, inappropriate stylistic toning, thematic irrelevance, and even blunt incoherence of verbal and visual features, etc. Due to the multimode nature of audiovisualtranslations some of the problems could easily be solved if translators actually watched the film,instead of hastily working on the script.Conclusions: Similar analysis of translators’mistakes is suggested as a means of teachingnovice translators to develop efficient tools of overcoming difficult cases while translatingforeign films.
LEXICO-SEMANTIC NEOLOGISMS IN THE CONTEMPORARY UKRAINIAN FEMALE PROSE
Authors: Г. Б. МІНЧАК
Published: April 2019

Introduction. The article focuses on the lexico-semantic units of the neology as a means of enriching figurative Ukrainian speech and as an important aesthetic component of the author's picture of the writer’s world.Purpose. The aim of the article is to describe and analyze the lexico-semantic innovations by using various criteria suggested by Liuko Dashvar, Dara Kornii, Lesia Romanchuk, Iren Rozdobudko.Methods. Systematization of the known directions and aspects applied while conducting the research within the descriptive method with its methods of external and internal interpretations proved it expedient to study the lexico-semantic units using the semantic-and-structural method,in particular the method of component and distributional analysis.Practical value of the results. The paper defines and describes the main varieties of lexico-semantic neologisms that function in contemporary fiction female prose. We suggest that these innovations may be classified according to the following criteria:1) the form of the linguistic unit: neolexemes (the novelty of the form is combined with the novelty of the content); transnominational neologisms (the combination of a new form of word with the expressed meaning of the already existed form); neosemems (new meaning is expressed by the form available in the language); neophrase;2) the degree of novelty (and by the way of nomination): absolute (strong) and relative as a result of borrowings;3) the functional purposes: nominative and nominative-expressive;4) the parameter of language – norm – speech: conventional (generally-accepted) and occasional (accidental).Conclusion. The conducted research shows that the role of contemporary authoresses in the development of the Ukrainian language is poly-dimensional. Thus, in particular, is the creation of neoforms with abstract-and-conceptual meaning and neosemantic units within the lexemeand its interconnectivity as well as actualization of the linguistic experience of the Ukrainian intelligentsia of the late XIXth – early XXth centuries and the connection with the cultural and written tradition of the Ukrainian language during historically ancient layers. Linguistic investigationsby Liuko Dashvar, Lesia Romanchuk, Iren Rozdobudko are aimed at discovering and developing natural, evolutionarily motivated content units of thinking. Their new discoveries are not sharply distinguished on the background of well-known words. The most vivid and most numerous lexicosemantic innovations are neosemantic units, performing the evaluative-expressive function.
LINGUAL MEANS OF THE INTERTEXTUALITY AND PRECEDENCY OF THE STREAM-OF-CONSCIOUSNESS POETRY (in Kenneth Koch poem “Sleeping with Women”)
Authors: Н. С. ЩАСЛИВА
Published: April 2019

Introduction. The article focuses on the intertextual specificity of the lingual means of intertextual and precedent categories in stream-of-consciousness facet of K. Koch poetic text “Sleeping with Women”. The relevance of the research is seen in studying various forms of above mentioned categories’ embodiment within postmodern poetry, ways of author's attitude, worldview, etc.The purpose. The paper aims at the studying of the aesthetic and organizing functions of intertextual and precedent signs within the poem of fragmentary discourse.Methods. Identification of the features of stream-of-consciousness’ poetry and the most productive means of realization of intertextuality and precedency along with description of the forms of their verbalization and functional features is possible due to applying the distributive, functional, stylistic and descriptive methods of analysis.Results. The most productive means of realization of intertextuality and precedency are precedent / intertextual names, situations, texts, and even quotations. They predominantly take universal and national precedent levels of precedency. Proper names are the means of space andtemporal determination of the text. They function at the same time as sense-forming phenomena.
2018 DRAFT UKRAINIAN ORTHOGRAPHY AS AN ATTEMPT OF ACTUALISATION OF TRADITIONAL ORTHOGRAPHIC RULES: URGENCY OF CHANGES AND ISSUES
Authors: Д. М. ПРИЙМАК
Published: April 2019

Introduction. A part of fundamental phonetical and morphological principles of the Ukrainian language were abolished by the occupation government of Russia in the course of the 1933 orthographic reform. This reform aimed at erasing distinctive features of the Ukrainian orthography and assimilating it into the Russian orthography. The current orthographic rules in Ukraine are based almost completely on the aforesaid centrally imposed changes. On August 15, 2018, the Ministry of Education and Science of Ukraine proposed its Draft Orthography as a step toward restoration of the traditional Ukrainian orthography.Purpose. The article aims at analysing the 2018 Draft Ukrainian Orthography and the main changes it seeks bringing to the orthographic rules currently in force in terms of their historical roots, and to reveal possible associated issues.Methods. Secondary research was used for collecting necessary data. Comparative analysis allowed revealing the source of proposed changes in the Ukrainian orthography. Deductive thinking was applied to investigate and assess possible issues.Results. The detailed consideration of the Draft Orthography has shown that the proposed changes are rooted in the orthographic rules stipulated in pre-1933 editions of the Ukrainian Orthography and academic Ukrainian dictionaries. Bringing these elements back to use and recognizing them officially as correct and inherent of the Ukrainian language system shouldbe seen as indispensable for subsequent harmonious development of the language. However, the 2018 Draft Ukrainian Orthography also has several significant shortcomings. Namely, it permits variance in almost all rules proposed, which might bring ambiguousness in a number of contexts. Also, the Draft Orthography fails to take into account other traditional rules ofthe Ukrainian language such as the dual number, certain flexions, etc., which have remained eliminated since 1933.Conclusion. The 2018 Draft Ukrainian Orthography aims at restoring traditional orthographic rules of the Ukrainian language and is based on pre-1933 editions of the Ukrainian Orthography and academic Ukrainian dictionaries. A number of issues should be addressed appropriately in order to integrate the new rules effectively.
A NEW WORK ON THE PECULIARITIES OF THE IDEOLOGIZATION OF LEXEMS IN INTERPRETATION DICTIONARIES
Authors: Г. Б. Мінчак
Published: April 2019

A NEW WORK ON THE Peculiarities of the IDEOLOGIZATION OF LICEMS IN INTERPRETATION DICTIONARIES: totalitarian and post-totalitarian dimensions of Renchka I. Lexicon of totalitarianism / Inna Renchka ; prev. L.T. Masenko. - K.: LLC "Klio Publishing House", 2018. - 232 p.
Energy-Aware Virtual Machine Clustering for Consolidation in Multi-tenant IaaS Public Clouds
Authors: Derdus Kenga Mosoti , Omwenga Vincent Oteke , Ogao Patrick Job
Published: April 2019

Cloud computing has gained a lot of interest from both small and big academic and commercial organizations because of its success in delivering service on a pay-as-you-go basis. Moreover, many users (organizations) can share server computing resources, which is made possible by virtualization. However, the amount of energy consumed by cloud data centres is a major concern. One of the major causes of energy wastage is the inefficient utilization of resources. For instance, in IaaS public clouds, users select Virtual Machine (VM) sizes set beforehand by the Cloud Service Providers (CSPs) without the knowledge of the kind of workloads to be executed in the VM. More often, the users overprovision the resources, which go to waste. Additionally, the CSPs do not have control over the types of applications that are executed and thus VM consolidation is performed blindly. There have been efforts to address the problem of energy consumption by efficient resource utilization through VM allocation and migration. However, these techniques lack collection and analysis of active real cloud traces from the IaaS cloud. This paper proposes an architecture for VM consolidation through VM profiling and analysis of VM resource usage and resource usage patterns, and a VM allocation policy. We have implemented our policy on CloudSim Plus cloud simulator and results show that it outperforms Worst Fit, Best Fit and First Fit VM allocation algorithms. Energy consumption is reduced through efficient consolidation that is informed by VM resource consumption.
An Experimental Investigation on the Strength Properties of Self Curing Concrete by Using Super Absorbrnt Polymer
Authors: Mohan Reddy V. Veera , Rasheed K. Mohammed
Published: April 2019

The super absorbent polymer (SAP) has the nature of absorbing large amount of water and converts into gel and at the same time it swells or a large amount of volume change occurs when SAP reacted with water. Main SAP agent is sodium polyacrylate . These properties are very useful and effective in plain concrete. It is proved that it has many positive effects on the properties of concrete in both stages; 1.fresh concrete, 2. hardened concrete. Super absorbent polymer is mainly having the water tightness properties of plain concrete with time. The study includes short term and long term effect of the super absorbent polymer on the water sealing properties. Many advantages exist in the use of super absorbent polymer in plain concrete with internal water. This internal water source acts as internal curing agent after the final setting of concrete. At the same time the SAP releases water at relatively slower rate at the fresh concrete stage. The SAP also provides additional voids in the concrete. These voids affect the concrete strength negatively at the same time improve the concrete performance by improving the concrete workability and consistency, reducing the concrete susceptibility to freezing thawing cycle, and improving concrete stability. In this project we tried to study the behavior of super absorbent polymer in mechanical properties of compression, split tensile and flexural strength with internally cured concrete. An experiment has been carried out for M50 concrete using Super absorbent polymer of 0%,0.2%,0.3%,0.4% and 0.5% respectively. concrete cubes, cylinders and beams are casted and tested for 7 days and 28 days. The results are discussed in detailed and the compressive strength and split tensile strength greater for 0.2% of sap when compared with the remaining percentages of sap concrete. 0.2% of sap is optimum for the Beam of size 700X150X150 mm and shows the high flexural strength.
Análise de desgaste em ferramentas de moagem aplicadas à indústria de processamento de cacau.
Authors: Santos DVJ , Silva FS , Medeiros LI , Medeiros NCFL
Published: April 2019

Este trabalho visa investigar porque certos tipos de ferramentas de moagem de cacau, conhecidos como martelos, resistem ao desgaste mais do que outros. Martelos são ferramentas de pequeno porte em formato de pêndulo constituídos do seu revestimento feito usualmente de metal duro (WC-Co) e do seu corpo feito em aço carbono que são severamente desgastadas durante o processo de pulverização de torta de cacau. Este trabalho buscou entender o porquê de martelos de três empresas fornecedoras sob as mesmas especificações técnicas solicitadas por uma certa empresa cliente variam tanto em durabilidade entre si. O estudo consistiu da análise das condições de desgaste, qualificação dos mecanismos de degaste, coleta de espécimes in loco e caracterização dos substratos. Os resultados mostraram duas das empresas apresentarem lotes que resistem consideravelmente mais em relação às taxas de desgaste percentual registradas. Os lotes de todas as empresas apresentaram defeitos superficiais como trincas e/ou defeitos de soldagem que podem vir a comprometer a durabilidade do material, entretanto, somente uma empresa apresentou resultados comprometedores. A variação de composição química também foi considerável, principalmente no nível de cobalto do revestimento. É sugerido estudos mais aprofundados isolando todas as variáveis para obter resultados mais precisos sobre as condições determinantes da falha.
Perspektif Atas Praktek Hubungan Industrial Di Wilayah Bogor
Authors: Firdaus Muhamad Azis , Yudhawati Diah
Published: April 2019

Penelitian ini bertujuan untuk mendapatkan gambaran atas praktek-praktek hubungan industrial pada berbagai bidang industri di wilayah Bogor dan sekitarnya. Metode survey dilakukan terhadap 108 responden yang dipilih secara acak. Responden terdiri dari karyawan yang berstatus sebagai karyawan tetap dan karyawan tidak tetap, yang bekerja di wilayah Bogor dan sekitarnya. Hasil penelitian uji beda atas jawaban responden menunjukan bahwa tidak ada perbedaan jawaban karyawan yang berstatus tidak tetap dengan karyawan tetap. Hasil analisis deskriptif dilakukan terhadap hasil instrumen yang sebarkan menunjukan bahwa terdapat dua indikator yang termasuk dalam kategori tidak baik yaitu proses penetapan gaji/upah, mekanisme pembayaran gaji/upah dan jenjang akrir. Sementara itu yang berstatus sangat baik yaitu keadilan dalam menggunakan fasilitas, pembagian jadwal lembur, kesempatan untuk terlibat dalam pengambilan keputusan, transfaransi perjanjian kerjasama, implementasi perjanjian kerjasama, dan keadilan dalam peraturan perusahaan.
Analisis Du Pont Untuk Mengukur Kinerja Keuangan Perusahaan
Authors: Damayanti Lusi , Yudhawati Diah , Prasetyowati Riris Aishah
Published: April 2019

Tujuan penelitian ini untuk mengetahui kinerja keuangan PT. Semen Indonesia Tbk dan PT. Indocement Tunggal Prakarsa Tbk dengan menggunakan Du Pont System. Penelitian ini menggunakan jenis data kuantitatif, sedangkan sumber data menggunakan data sekunder dengan teknik pengumpulan data studi pustaka (Library Research). Berdasarkan hasil penelitian disimpulkan bahwa kinerja keuangan pada PT. Semen Indonesia Tbk dan Indocement Tunggal Prakarsa Tbk. Menggunakan Du Pont System menunjukan kinerja keuangan pada PT. Semen Indonesia Tbk selama 6 tahun dari tahun 2012 – 2017 diperoleh Return On Equity dengan rata – rata 17,01%. Pada PT. Indocement Tunggal Prakarsa Tbk diperoleh rata – rata Return On Equity sebesar 18,69%, dapat dikatakan efisien dalam menggunakan modal. Perusahaan disarankan efisien dalam penggunaan modal dengan meningkatkan penjualan dan mengoptimalkan total aktiva, sehingga mendapatkan tingkat pengembalian Return On Investment yang tinggi dan menambah total aktiva tanpa meningkatkan total ekuitas perusahaan agar menghasilkan Equity Multiplier yang diharapkan dengan begitu Return On Equity akan meningkat.
Counseling in Botswana: History, Current Status and Future Trends
Authors: Jabulani Allen Muchado Dr.
Published: April 2019

The article presents an overview of counseling in Botswana, an update of the history, current status, anticipated future trends and challenges in light of the social and educational development in the country. Counseling in Botswana has evolved over years. The initial effort started in 1963 with an introduction of career guidance in secondary schools. The development of guidance and counseling programs for schools has influenced a number of psychosocial intervention services and training programs. A number of training programs emerged at Colleges of Education and at the University of Botswana. All these developments had several challenges in the area of developing robust professional counseling service statues. The article discusses the current status, future trends in counseling and make recommendations for future development of the profession in Botswana.
Integrated Economic Empowerment Model for Rural Islamic Barding Schools in West Borneo Indonesia
Authors: Alhifni Anas , Ahwarumi Biyati , Huda Nurul
Published: April 2019

This study was conducted in a traditional Islamic boarding school (IBS) located in West Kalimantan. Among the existed boarding schools in the area, Pondok Pesantren Abdussalam was chosen due to its potential. This study adopted qualitative approach, utilized observation, documentation, interview and focus-group discussion (FGD) technique in collecting the data which then being analyzed using action research technique. The originality of the study is as follow: the study in this topic area has not been conducted previously, especially the one which focuses on the integrated economics improvement of IBS in rural area. The study result shows that there have been some economic activities in the institution in spite of its remote location. Additionally, the economic activities have been provided the institution with some benefits. However, the effect of such activities have not been felt fully yet. There have been three reasons in regard with this situation, namely insufficient human resources who have expertise in existed economic sector, limited capital as well as infrastructure factor. We propose the synergetic model to solve these three issues. The model is a cooperative model which can be implemented both with internal institution such as internal sharia micro-finance institution or with external institution such as local government or universities.
Parenting Styles as a Function of Academic Achievement
Authors: Tekle Woldearegai Bisrat , Babita Das Dr.
Published: April 2019

The study investigated the relationionship between parenting behaviors and academic achievement. The objective of the study was to inquire the functions of parenting on academic achievement. The study was conducted in Tulu Yombo Junior School, Oromia regional state, Ethiopia. The study was conducted from January 2018 up to September 2018. The study employed a cross-sectional research design. The population of the study was 200 students of grade 7 and 8. Subsequently, 50(25%) samples were selected using stratified random sampling. The study was a pure quantitative research type. For this reason, it used a survey questionnaire which is close-ended to identify the styles of parenting the parents of the students employed. The questions were prepared to be responded in “Likert Scales”. On the other hand, record scores of academic achievement were used as secondary data. The data were analyzed and interpreted using One-way ANOVA and Honestly Significance Difference (HSD) statistical test. The result of the study revealed that children of Authoritative (democratic) parents scored (x̅ =80.75) significantly higher in their academic achievement than did children from Non-authoritative. However, no substantial difference was observed in the academic achievement of students from authoritarian (x̅ =61.3), indulgent (x̅ =53.8) and neglectful parents (x̅ =52.4).
A Study of Japanese Immigrant in Thailand; Push and Pull Factors Since 2002
Authors: Limsiritong Thanapum , Furutani Tomoyuki , Chansatitporn Prapassorn , Limsiritong Karnjira
Published: April 2019

Japanese immigrant has become very momentous situation in Thailand development over a decade as same as Chinese migrant movement to global migration labor. The situations have developed from economic values merge to social adaptation and 2nd generation. The implementation for this research could lead to understanding of few Japanese migrant situation studies in Thailand which relates to developments situation, social credibility, and skilled labor from 2002 until the present. The research aims (1) to find out and clarify the push and pull factors of Japanese immigrant in Thailand to indicate the Japanese migration role, (2) to analyze the role of Japanese immigrant in Thailand through nationality issues and (3) to indicate migrant management system reconstruction in Thailand in the future. This research is a critical study case of documentary research from the accessible secondary data, PEST analysis (Political with economic, society, and technology) is used to analyze in clarifying of macro push and pull factors of external concerned points with relate to government and Japanese migrant until the few studies of 2nd Japanese migrant in Thailand possibly. According to Thailand and Japan situations that might be concerned to Japanese migrant in Thailand, the long-term effect of Japanese immigrant will cultivate to Thailand society over generation in the sense of migrant management. As the first step of this study, tourists, non-immigrants, immigrants and 2nd generation of immigrants are issues compared and future approach possibly. Results of this study indicate; (1) The role of Japanese migrant push and pull factors are the essential point of development issues, (2) A few 2nd generation study of Japanese migrant in Thailand is crucial for government approach. (3) Limitation of migrant management system which relates to Japanese. Consequently, Japanese migrant increasing in Thailand; investment part to social adaptation and next generation migrant, the government should realize to reallocate the migration system such as social credibility from state/ company/ local government to Japanese migrant group. This study would strengthen linkages between Thai and Japanese sectors (investment enterprises, society, and positive diversity cultivation).
Influence of Age group on Job Satisfaction in Academia
Authors: Shrestha Milan
Published: April 2019

Purpose - Job Satisfaction (JS) has seen an upsurge concern in the arena of school management and it is highly associated with the age groups of school teachers. Thus, this study focused to ascertain the level of JS and examine it via age groups of school teachers.  Design - The scholar applied a cross-sectional survey design in post-positivist paradigm. The data were amassed from 345 school teachers of a cluster via self-administer questionnaire and analyzed with descriptive statistics and ANOVA test.  In the meantime, social exchange theory was employed to scrutinize the results.  Findings - This study found that the school teachers expressed moderate satisfaction in the job.  Likewise, the age groups significantly influence the JS among school teachers.  More specifically, the senior age group teachers expressed more satisfaction in the job than other groups of the teacher.  Subsequently, these job satisfied teachers contribute to more job commitment, effectiveness and work performances in the school. Furthermore, JS facilitates school to achieve elevated academic success.  Implications - The study endows with the concrete approach for other forthcoming scholar to explore the contribution of age groups on JS among academia.
ANALISIS PROSES PENERIMAAN TENAGA KEPERAWATAN DALAM MENINGKATKAN MUTU PELAYANAN KEPERAWATAN
Authors: Suryanti Heny
Published: April 2019

Abstrak
 
Tujuan pembangunan kesehatan Indonesia sehat 2015 adalah meningkatkan kesadaran, kemauan dan kemampuan hidup sehat bagi setiap orang agar terwujud derajat kesehatan masyarakat yang optimal melalui terciptanya masyarakat, bangsa, dan negara Indonesia ditandai oleh penduduknya hidup dalam lingkungan dengan perilaku yang sehat, memiliki kemampuan untuk menjangkau pelayanan, fasilitas kesehatan yang bermutu secara adil dan merata di seluruh wilayah Republik Indonesia dapat mewujudkan bangsa yang mandiri maju dan sejahterah. Rancangan penelitian menggunakan deskriptif kualitatif. Informan Penelitian 1 orang Direksi, 1 orang SDM, 1 orang Tim seleksi penerimaan, 1 orang bagian Keperawatan, 1 orang Komite Keperawatan, 5 orang perawat berpengalaman minimal 5 tahun bekerja, 3 orang pasien rawatan pasien. Instrumen Penelitian berupa wawancara (indepth interview). Teknik analisa data berupa analisis kualitatif. Teknik validitas dengan metode triangulasi. Hasil penelitian menunjukkan Kebijakan RSU X berkaitan dengan proses penerimaan perawat sesuai Surat Keputusan Direktur Utama Rumah Sakit X tentang Pedoman Kerja (SDM) dan SOP SDM RSU X tentang Seleksi dan Rekrutmen Tenaga Kesehatan. Metode proses penerimaan tenaga perawat di RSU X menunggu lamaran masuk terutama berasal dari Akademi Keperawatan milik Yayasan X. Pelamar dari luar Akademi Keperawatan Yayasan RSU X tetap diterima, tetapi prioritas utama penerimaan tenaga keperawatan dari Akademi Keperawatan RSU X, karena banyak memakai sumber dari Akademi Keperawatan Yayasan X maka perawat baru diharapkan segera beradaptasi di lingkungan kerja. Penjenjangan karir di RSU X yaitu Perawat Klinik I- IV walaupun belum maksimal dan proses mapping dari kompetensi, masa kerja, dan pendidikan. Untuk menjaga kualitas dan kemampuan perawat, RS memberikan beasiswa pendidikan bagi perawat, mengadakan pelatihan atau mengirim tenaga perawat yang mampu mengikuti pelatihan diluar RSU X. Setiap perawat mempunyai penilaian terhadap kinerja keperawatan (raport) dan SDM (formulir). Proses penerimaan mempunyai kekuatan berupa kebijakan dan SOP yang jelas, tetapi RSU X belum memiliki panitia khusus pelaksanan tenaga keperawatan sehingga proses penerimaan tenaga keperawatan tanggung jawab bidang SDM dibantu bagian keperawatan. Hal ini menjadi kelemahan RSU X karena proses penyeleksian belum objektif untuk menghindarkan bias.
EFEKTIVITAS PENERAPAN ISO 9001:2008 DI UNIT SARANA DAN PRASARANA RSUD X TAHUN 2014
Authors: Darmi Salfia
Published: April 2019

ABSTRAK
ISO 9001:2008 adalah salah satu standar dalam menentukan baik buruknya suatu pelayanan kesehatan. Studi pendahuluan penelitian bulan Juli-Agustus 2014 terdapat beberapa masalah dalam pelaksanaan  ISO 9001:2008 di Unit Sarana dan Prsarana RSUD X, diantaranya masih adanya kekosongan jabatan. Tujuan penelitian ini adalah untuk mengetahui keefektifitasan pelaksanaan ISO 9001:2008 di Unit Sarana dan Prasarana RSUD X. Metode penelitian yang digunakan adalah kualitatif. Teknik tang digunakan dalam pengambilan data yaitu dengan melakukan wawancara mendalam, observasi dan dokumentasi menggunakan catatan observasional dan dokumen yang didapatkan dari pihak unit sarana dan prasarana. Hasil penelitian ini mendapatkan temuan pelaksanaan ISO 9001:2008 di Unit Sarana dan Prasarana RSUD X tidak efektif dilaksanakan karena di ruangan administrasi UPRS masih ada peralatan yang belum dilengkapi seperti 1 unit lemari suku cadang, tidak adanya surat tugas pelatihan yang dilakukan oleh petugas dan sertifikat, tidak adanya pendokumentasian yang lengkap,  masih adanya jabatan yang belum terisi, masih adanya saran – saran yang diberikan tim audit untuk unit sarana dan prasarana. Dari hasil penelitian dapat disimpulkan bahwa belum efektifnya pelaksanaan ISO 9001:2008 di RSUD X tahun 2014. Disarankan pada unit sarana dan prasarana untuk memperbaiki semua unsur baik , kelengkapan sarana pencegahan, mengisi jabatan yang kosong agar ISO 9001:2008 dapat terlaksana secara efektif.
Hubungan Karakteristik Keluarga, Ekonomi, dan Faktor Lain dengan Stunting, Wasting dan Underweight pada Anak Usia 6-23 bulan di Indonesia
Authors: Badriyah Lulu
Published: April 2019

Malnutrisi pada anak menghambat pembangunan manusia dan mengakibatkan dampak serius baik jangka pendek maupun jangka panjang. Stunting, wasting dan underweight merupakan ekspresi dari malnutrisi. Penelitian ini bertujuan untuk menganalisis faktor yang berhubungan dengan stunting, wasting, dan underweight di Indonesia. Desain studi penelitian ini adalah cross sectional dengan menggunakan data survey nasional Riskesdas 2013. Populasi penelitian adalah seluruh rumah tangga yang mewakili 33 provinsi dan mempunyai anak usia 6-23 bulan. Jumlah sampel sebanyak 7.668 anak. Analisis data dilakukan menggunakan uji regresi logistik. Hasil penelitian didapatkan anak usia 6-23 bulan di Indonesia yang mengalami stunting sebesar 34,7%, wasting 14,3%, dan underweight 15,4%.  Hasil analisis multivariate menunjukkan bahwa jenis kelamin, BBLR, ASI eksklusif, dan status ekonomi berhubungan signifikan dengan stunting. Jenis kelamin, BBLR, dan jumlah ART berhubungan signifikan dengan wasting. Jenis kelamin, BBLR, jumlah ART, dan status ekonomi berhubungan signifikan dengan underweight. Saran penelitian adalah perlunya pendekatan multisektor untuk mengentaskan masalah gizi pada anak, terutama harus memperhatikan kesehatan dan kebutuhan gizi ibu selama kehamilan untuk mencegah BBLR.
Statistical approach for selection of regression model during validation of bioanalytical method
Authors: Nakov Natalija , Tonic-Ribarska Jasmina , Dimitrovska Aneta , Petkovska Rumenka
Published: April 2019

The selection of an adequate regression model is the basis for obtaining accurate and reproducible results during the bionalytical method validation. Given the wide concentration range, frequently present in bioanalytical assays, heteroscedasticity of the data may be expected. Several weighted linear and quadratic regression models were evaluated during the selection of the adequate curve fit using nonparametric statistical tests: One sample rank test and Wilcoxon signed rank test for two independent groups of samples. The results obtained with One sample rank test could not give statistical justification for the selection of linear vs. quadratic regression models because slight
differences between the error (presented through the relative residuals) were obtained. Estimation of the significance of the differences in the RR was achieved using Wilcoxon signed rank test, where linear and quadratic regression models were treated as two independent groups. The application of this simple non-parametric statistical test provides statistical confirmation of the choice of an adequate regression model.
Synergy of novel coumarin derivatives and tamoxifen in blocking growth and inducing apoptosis of breast cancer cells
Authors: Ballazhi Lulzime , Imeri Faik , Dimovski Aleksandar , Jashari Ahmed , Popovski Emil , Breznica-Selmani Pranvera , Mikhova Bozhana , Dräger Gerald , Alili-Idrizi Edita , Mladenovska Kristina
Published: April 2019

Possible synergistic effect of tamoxifen (2 μM) and hydrazinyldiene-chroman-2,4-diones (10-100 μM) was examined with an aim to create more effective treatment for ER+ breast cancer. Anti-breast cancer effect has been evaluated on the proliferation of MCF-7 breast adenocarcinoma cells using MTT and alamarBlue assays. Cell viability was evaluated after 48h-treatment and the ICs50 of the coumarin derivatives were determined. The apoptotic effect was evaluated by detection of PARP cleavage and reduced activity of the survival kinase Akt. The results demonstrated dose-dependent activity, with a percent of growth inhibition after combination treatment being significantly higher (53% to 79%, 10 μM and 100 μM, respectively) than the one in the cell lines treated with tamoxifen (29% to 37%) and the synthesized coumarin derivatives alone (11% to 68%, 10 μM and 100 μM, respectively). The ICs50 of the synthesized compounds significantly decreased in synergy with tamoxifen (33% to 51%). Coumarin derivative having thiazole moiety with additional methyl groups attached
to the carbons at positions 5 and 4 in the thiazole ring showed to be the most potent, with IC50 20 µM when administered alone and 10 µM in synergy with tamoxifen. The levels of phospho-Thr308 Akt were down-regulated by the combination treatment, pointing to tyrosine kinase phosphorylation inhibition. In conclusion, the novel coumarin derivatives enhance the activity of tamoxifen and this combination may
be suitable for prevention of ER+ breast cancer or development of related compounds. Further studies are needed to elucidate precisely the type of receptor involved in the activity and the mechanism of action.
Chemical composition of Chenopodium botrys L. (Chenopodiaceae) essential oil
Authors: Adji Andov Ljubica , Karapandzova Marija , Cvetkovikj Ivana , Stefkov Gjose , Kulevanova Svetlana
Published: April 2019

Chemical composition of essential oil isolated from aerial parts of Chenopodium botrys L. (Chenopodiaceae) collected from five different locations in the Republic of Macedonia was analysed by GC/FID/MS. Seventy five compounds were identified representing 90.02- 91.24% of the oil. The analysis has shown that the oils were rich in sesquiterpenе components (83.18-87.54%) comprising elemol acetat (9.88%-21.98%), seline-11-en-4α-ol (9.81%-13.5%), selina-3,11-dien-6α-ol (6.42%-9.71%) and elemol (5.57%-9.49%) as major oxygen containing sesquiterpenes, followed by lower content of α-eudesmol acetat (3.24%-4.11%), α-chenopodiol (2.42%-5.43%), botrydiol (1.87-5.73%) and α-chenopodiol-6-acetat (1.9%-4.73%).
Effects of Valsartan vs Amlodipin on renal function in salt loaded spontaneously hypertensive rats
Authors: Gjorgjievska Kalina , Zafirov Dimce , Jurhar Pavlova Maja , Cekovska Svetlana
Published: April 2019

The goal of this study was to compare the effects of valsartan and amlodipin on the systolic blood pressure and parameters specific to the renal function in salt loaded spontaneously hypertensive rats (SHR). 32 male SHR were used at age of 20 weeks and body weight ranging between 265-300 g. From 8 weeks of age tab water was replaced with a solution of NaCl (1%) given ad libitum. Rats were divided into 2 groups: valsartan treated group SHRVAL (n=16) in which valsartan was given at a dose of 10 mg/kg b. w. and amlodipine treated group SHRAMLO (n=16) in which amlodipine was given at a dose of 5 mg/kg b. w. For a period of 12 weeks we have evaluated the effect of the investigated drugs on systolic blood pressure, body weight and renal function tests. In salt loaded rats amlodipine was more effective in reducing the systolic blood pressure in contrast to valsartan who had more pronounced effect on renal parameters most evident in proteinuria. Since both treatment groups have different mechanism of action a combination therapy may be beneficial in improving renal function in SHR rats.
Formulation of synbiotic soy-based food product with antihypertensive potential
Authors: Jurhar Pavlova Maja , Mladenovska Kristina , Petreska Ivanovska Tanja , Petrushevska-Tozi Lidija , Korneti Petraki , Karchev Vasil , Panovski Nikola , Petrovska Milena
Published: April 2019

The specific aims of this study were to select the favorable prebiotic for L casei-01 as well as the suitable inoculum of the probiotic for fermented soy with ACE-inhibitory potential. For that purpose the metabolic activity of L casei-01 in soymilk supplemented with (1.5% w/v) prebiotics Fructooligosaccharide (FOS) or oligofructose enriched inulin (Synergy 1) was assessed. The evaluated parameters were: pH, viable cell counts, proteolysis, organic acid production and inhibition of angiotensine converting enzyme activity (IACE). The cell growth of L casei-01 reached the recommended therapeutic level of 9.58 ± 0.035 log cfu mL-1 for low inoculum samples (0.005 and 0.01%w/v) and 11.543 ± 0.13 log cfu mL-1 for high inoculum samples (0.075 and 0.1%w/v) regardless of the prebiotic used. The lower pH during fermentation, faster cell growth and superior proteolysis in Synergy 1 samples indicated better utilization of that prebiotic vs. FOS.
The hydrolysis depended on the prebiotic used, showing higher values in Synergy 1 samples. The faster proteolysis was confirmed by SDSPAG electrophoresis. The Mw of polypeptides in the synbiotic end-products were lower than 30kD. The observed values for inhibition of ACE activity were app. 71, 74, 77 and 78% for inoculum rates of 0.005, 0.01, 0.075 and 0.1% w/v, respectively. Based on the results obtained in our study, the prebiotic Synergy 1 (1.5% w/v) and L. casei-01 at inoculum of 0.01% w/v for low dose
and 0.075% w/v for high dose were considered more favorable for the production of synbiotic soy drink with antihypertensive potential.
Bioinspired bioartifical polymer hybrid composites for propolis
vaginal delivery II: formulation and characterization
Authors: Glavas-Dodov Marija , Simonoska-Crcarevska Maja , Slavevska Raicki Renata , Sibinovska Nadica , Mladenovska Kristina , Zafirovska-Gapkovska Ana
Published: April 2019

In our previous work Box-Behnken experimental design was applied for formulation optimization of the thermoreversible mucoadhesive in situ vaginal hydrogels with propolis and optimized batches were identified. Optimized batches of bioartificial polymer hybrid composites (chitosan, Lutrol® F-127 and Lutrol® F-68 mixture)) (CP1, CP2, CP3) were prepared using so-called cold method. Formulation P3 (chitosan free) was prepared in order to evaluate the effect of chitosan on the physico-chemical and biopharmaceutical properties of the polymer hybrid composites (gels).
The pH values of the gels were 4-4.5. The gelation temperature for all formulations was in a range of 29-33 o C. Total flavonoids content was above 95%. Increase in concentration of Lutrol® F-127 and Lutrol® F-68/Lutrol® F-127 ratio lead to a higher viscosity values and slower gel erosion/dissolution. The presence of chitosan increased gel viscosity and hence slow-down erossion/dissoluiton. Propolis
release rate was the highest in P3 which released propolis within 5 h, corresponding to time of complete erosion. The same correlation between erosion process and drug release rate was observed in CP1-CP3, where prolonged propolis release for more than 10 h was achieved. Microbiological quality was in accordance with the requirements of Ph. Eur. 7. All formulations demonstrated adequate stability at 5 ± 3 °C
during 6 months. Based on overall results it can be anticipated that bioartificial blended bioinspired polymer hybrid composites for propolis vaginal delivery could represent intelligent delivery systems with physicochemical and biopharmaceutical properties in favor or efficacious and safe therapy of vaginal infections.
Involvement of serum HSP 70 in Guillain-Barré Syndrome: An exploratory study and a review of current literature
Authors: Loshaj-Shala Aida , Poceva Panovska Ana , Brezovska Katerina , Beretta Giangiacomo , Suturkova Ljubica , Apostolski Slobodan
Published: April 2019

The evolutionary conserved family of heat shock proteins (HSP) is responsible for protecting cells against different types of stress. Although the levels of HSP can be readily measured in serum, the levels of HSP 70 in patients Guillain-Barre Syndrome (GBS) have not been studied before. To this aim we investigate whether patients with GBS (n=21) had altered serum HSP 70 levels compared to healthy controls (HC, n=9) and to patients affected by other immune disorders such as multifocal motor neuropathy (MMN, n=4) and chronic inflammatory demyelinating polyneuropathy (CIDP, n=6). The highest HSP 70 value (15.78 ± 1.72 ng/mL) was found in one patient in the GBS group, although we have found that serum HSP70 levels were significantly higher in 2 out of the 21 GBS patients (9.5%). Hence, it is of interest to underline that the patient with the highest HSP70 level, had also the best recovery rate. Моrе extensive research is required in order to support the hypothesis that HSP 70 serum concentration may be a useful biomarker for the prediction of remission outcome for GBS patients.
Immunohistochemical study of the inflammatory response of the dental pulp
Authors: Sotirovska Ivkovska Ana , Zabokova-Bilbilova Efka , Georgiev Zlatko , Ivkovski Ljube
Published: April 2019

Defense reactions of the dental pulp involve a variety of biological reactions, in which the immune system plays a very important role. The class II major histocompatibility complex (MHC) molecule expressing cells, termed dendritic cells and lymphocytes in human dental pulp are highly sensitive to exogenous antigenic stimuli. Their drastic changes in number and localization are induced by dental caries. This study investigated the responses of the immune system in two different clinical conditions: shallow and deep cavities. Cells were identified immunohistochemically by using the following monoclonal antibodies: HLA-DR, CD45RO and CD20. Initial pulpal
response was characterized by a localized accumulation of HLA-DR antibody-positive cells in the pulp tissue beneath the dentinal tubules communicating with the caries lesion. In the pulp of progressed caries, a large number of HLA-DR-positive cells was observed with a marked increase of other kinds of immunocompetent cells. This might indicate the occurrence of antigen presentation locally in the pulp tissue, which is very important for the immune response. Results obtained in this study demonstrated that dental pulps respond to the progression of the carious lesion and cellular and humoral
immune responses occur in the pulp tissue.
Pola dan Skala Usaha Pembesaran Ikan Bandeng di Kecamatan Muara Gembong Kabupaten Bekasi
Authors: Wiryati Ganjar
Published: April 2019

Tujuan penelitian ini adalah untuk mengetahui bagaimana tingkat pendapatan pembudidaya ikan bandeng pada pola usaha yang berbeda di Kecamatan Muara Gembong, Kabupaten Bekasi, Provinsi Jawa Barat. Sehingga pada akhirnya akan memberikan manfaat sebagai sumber informasi bagi pembudidaya ikan bandeng di Kecamatan Muara Gembong pentingnya mengetahui tingkat pendapatan sesuai dengan biaya produksi yang di keluarkan pada pola usaha yang berbeda. Penelitian dilakukan dengan menggunakan pendekatan kuantitatif dan kualitatif. Data yang digunakan adalah data primer yang diperoleh dari hasil wawancara dengan responden. Sampel responden ditentukan secara simple random sampling. Analisis data yang digunakan adalah analisis kelayakan usaha dan analisis deskriptif. Hasil penelitian menyatakan tingkat pendapatan yang ditunjukkan dari hasil data responden bahwa tingkat pendapatan terbesar berada pada kegiatan usaha polikultur dua komoditas antara bandeng dan udang, dan tingkat berikutnya diduduki oleh polikultur bandeng dan rumput laut, sedangkan budidaya bandeng secara monokultur berada pada tingkat yang paling bawah. Pola usaha yang dilakukan kegiatan budidaya secara polikultur menunjukkan hasil yang lebih tinggi pendapatannya di bandingkan dengan pola monokultur, sebab pada usaha polikultur ada dua komoditas yang di pelihara masing-masing menyumbangkan pendapatan sesuai dengan komoditas yang di usahakan.
Identifikasi Infeksi Ektoparasit pada Ikan Mas (Cyprinus carpio L.) di Perairan Waduk Darma, Kabupaten Kuningan Provinsi Jawa Barat
Authors: Eliyani Yuke
Published: April 2019

Penelitian ini bertujuan untuk mengidentifikasi serangan infeksi ektoparasit pada ikan mas (Cyprinus carpio) yang perairan Waduk Darma Kabupaten Kuningan, Provinsi Jawa Barat, pada bulan Agustus 2017. Identifikasi dan analisa ektoparasit dilaksanakan di Laboratorium Kesehatan Ikan, Departemen Akuakultur, Institut Pertanian Bogor. Hasil identifikasi menunjukkan terdapat tiga jenis parasit yang memiliki nilai prevalensi yang sama yaitu sebesar 66,67: Trichodina sp., Epistylis sp., serta Gyrodactylus sp.Nilai prevalensi tertinggi dicapai oleh parasit Dactylogyrus sp, namun dominansi parasit (7,53) ini tidak mencapai nilai tertinggi. Adapun nilai dominansi dan intensitas tertinggi diperoleh parasit Epistylis sp. dengan nilai sebesar 69,49 dan 715,40. Terdapat hasil yang menarik dari penelitian ini, dimana lima jenis parasit dari total 10 parasit yang ditemukan adalah dari golongan Monogenea (Cichlidogyrus sp., Gyrodactylus sp., Heterobothrium sp., Diplozoon sp., serta Dactylogyrus sp.).
Komunikasi Penyuluhan pada Pengelolaan Sumberdaya Perikanan Berbasis Kearifan Lokal
Authors: Ranum Garudhea Asmara Rona
Published: April 2019

Pengembangan masyarakat melalui upaya pemberdayaan nilai-nilai kearifan lokal dewasa ini mengalami kemerosotan karena pengaruh globalisasi dan otonomi daerah. Selain itu, terjadi diskomunikasi antara Penyuluh dengan masyarakat menyebabkan penerapan metode penyuluhan di daerah sering tidak efektif. Pemberdayaan masyarakat melalui kegiatan penyuluhan dilakukan untuk mengembangkan pengelolaan sumberdaya kelautan dan perikanan. Pada dasarnya aktivitas ini adalah proses mentransformasi sumber daya alam yang ada di masyarakat sebagai salah satu upaya juga dalam menanggulangi kemiskinan secara mandiri di wilayah tersebut dengan memanfaatkan nilai-nilai kearifan lokal yang seharusnya dapat menjadi tulang punggung kesuksesan pelaksanaan kegiatan pemberdayaan melalui penyuluhan di daerah. Tujuan penulisan ini adalah mengkaji strategi komunikasi merupakan paduan dari perencanaan komunikasi dan manajemen komunikasi untuk mencapai suatu tujuan penyuluhan.
Селевые явления в Узбекистане
Authors: Ахмедов Машрап , Салямова Клара
Published: April 2019

Проведен анализ селевых явлений на территории Узбекистана, которые в основном являются трансграничными с Кыргызстаном и Таджикистаном. В целом по республике площадь бассейнов селеактивных водотоков составляет 53 770 км2 (12 % от общей площади территории республики) при количестве селеактивных водотоков – 709. Подробно для каждой из областей Узбекистана приведен ущерб от произошедших в разные годы селевых явлений. Cерьезную опасность представляют селевые потоки, формирующиеся в предгорьях и холмистых местностях, которые занимают треть горной площади республики. Это небольшие, дробно расчлененные, складчатые возвышенности высотой 800–1200 метров, лишенные растительного покрова и изрезанные суходолами. В весенне-летний период практически все предгорья становятся в той или иной мере селеопасными. Приведены факторы селевой активности и проблемы их прогнозирования, а также указана необходимость мероприятий для полного решения вопроса прогнозирования и защиты от селевых явлений в Узбекистане.
Научно-практический комментарий к статье 23.58 Кодекса об административных правонарушениях Республики Беларусь
Authors: Пасовец Елена , Бордак Сергей Сергеевич
Published: April 2019

В статье исследуется современная административная норма, предусматривающая ответственность за нарушение законодательства в области защиты населения и территорий от чрезвычайных ситуаций, сформирован юридический состав двух ее частей, основания применения; уделено внимание процессуальному алгоритму реализации административной ответственности за нарушение законодательства в области защиты населения и территорий.