bluuebunny/crossref_metadata_2025 huggingface dataset:
EFFECT OF EXERCISE ON INSULIN RESISTANCE IN OBESE TYPE 2 DIABETES PATIENTS
Authors: Zhang Bin
Published: January 2022

ABSTRACT Introduction: Type 2 diabetes mellitus (T2DM), also known as non-insulin-dependent diabetes mellitus (NIDDM), accounts for more than 90% of the total number of diabetes mellitus cases and often occurs in middle-aged and elderly people. Objective: To investigate the effect of exercise intervention on insulin resistance in obese type 2 diabetes patients. Methods: Eighty-six obese diabetic patients were screened as experimental subjects in physical examinations and randomly divided into observation and control groups. Visceral fat volume, fasting blood glucose, and fasting insulin of all subjects were measured before and after completion of the 6-month experimental implementation. The insulin resistance was calculated for both groups and the values for each indicator were compared statistically between groups. Results: Control of body weight, body mass index, blood glucose, blood lipids and insulin resistance index were better in the observation group than in the control group, and the difference was statistically significant (P < 0.05). Conclusions: Basal intervention with quantitative exercise can significantly improve insulin resistance in obese type 2 diabetes patients and the effect is better than treatment with diet and conventional exercise. Level of evidence II; Therapeutic studies - investigation of treatment results.
EFFECT OF DIFFERENT INTERVAL SPEED TRAINING ON ATHLETE REACTION
Authors: Chen Hongqiang
Published: January 2022

ABSTRACT Introduction: High-intensity Intermittent Training (HIIT) ranked first in the ACSM “2013 Global Training Methodology Survey”. Objective: To explore the influence of different speed training intervals on athlete reaction speed. Methods: Sixteen male bicycle athletes were randomly divided into two groups. The two groups then completed a six-week training routine (NT). The two groups then completed a six-week training routine , started 6 weeks of Sprint Interval Training (SIT) (a total of 12 lessons), with SIT instead of Normal Training (NT) live endurance training, and another training remains unchanged. Results: After 6 weeks of NT, Pmax GXT in the CG and DG groups decreased by 0.7% and 1.7%, respectively,as compared to the pre-training numbers. The difference was not statistically significant (P>0.05). And after 6 weeks of SIT, Pmax GXT increased significantly (P<0.05) in both experimental groupss,with increases of 9.2% and 10.2% for the CG and DG groups, respectively. Conclusions: The results show that intermittent training can effectively improve the aerobic metabolism of short-haul cyclists. As the power bicycle load and the training intensity and volume of the deceleration intermittent training program increase, the more significant the changes in aerobic capacity that can result in adaptability. Level of evidence II; Therapeutic studies - investigation of treatment results.
PHYSICAL ACTIVITY IN THE TREATMENT OF DEPRESSION IN COLLEGE STUDENTS
Authors: He Xiaowei
Published: January 2022

ABSTRACT Introduction: The mental health of college students is getting more and more attention from society. Physical exercise as a means of psychotherapy and mental health has become common at home and abroad. Objective: We explore the effect of prescribing physical exercise in the treatment of depression in college students. Methods: College students who had been diagnosed with depression were randomly divided into an observation group and a control group, each with 18 patients. The control group received drug treatment. The observation group received sports therapy in addition to drug therapy. Results: There was a statistically significant difference in HAMD scores between the observation and control groups in the first week (P<0.01). Conclusions: Exercise can play a role in treating depression patients rapidly, safely, and efficiently. Level of evidence II; Therapeutic studies - investigation of treatment results.
Acute and subchronic effects of petroleum on the freshwater fish Hoplias aff. malabaricus
Authors: Santos R. M. , Petry A. C. , Sousa V. L. , Souza H. O. , Azevedo A. , Soares A. R. , Weber L. I.
Published: January 2022

Abstract Petroleum water soluble fraction (WSF) impairs organisms, but damages may vary among cell and tissue levels. The aim of the present study was to evaluate the acute (24 h, 48 h, 72 h) and subchronic effects (36 days) of WSF (0%, 25% and 100%) in juveniles of the Neotropical top predator fish Hoplias aff. malabaricus. The effects of WSF were evaluated at a molecular level using the comet assay and micronucleus test for genome damage; and at a morphological level through histological identification of liver pathologic lesions. In both acute and subchronic exposure we found low levels of DNA damage (< 10% of comet tail) and non-significant frequency of micronucleus in WSF exposed fish. The most significant liver lesions in WSF exposed fish were fatty vacuolization, hypertrophy and focal necrosis. Since these tissue injuries were progressive and persistent, their irreversibility may negatively affect fish recruitment, even in a such resistant top predator.
Effects of Pasturella Multocida B:2 and its immunogens (LPS and OMP) on reproductive hormones in Nili-Ravi Buffaloes
Authors: Zaman A. , Roohi N. , Irfan M.
Published: January 2022

Abstract Livestock is a fundamental part of the agriculture industry in Pakistan and contributes more than 11.53% to GDP. Among livestock species, the buffaloes are regarded as the black gold of Pakistan. Being the highest milk producers globally, Nili-Ravi buffaloes are the most famous ones. Buffaloes are affected by many endemic diseases, and "Hemorrhagic septicemia" (HS) is one of them. This study was designed to ascertain the effects of experimental exposure ofP. multocida B:2 (oral) and its immunogens, i.e., LPS (oral and intravenous) and OMP (oral and subcutaneous) on reproductive hormonal profiles in Nili-Ravi buffaloes. Repeated serum samples were collected from the jugular vein of experimental animals for 21 days (0, 02, 04, 08, 12, 16, 20, 24, 36, 48, 72, 120, 168, 216, 264, 360, 456 and 504 hours). Hormonal assays to determine the serum concentrations of Gonadotropin-releasing hormone (GnRH), Follicle-stimulating hormone (FSH), Luteinizing hormone (LH), Estrogen (E2) and progesterone (P4) were performed using (MyBioSource) commercial Elisa kits. The hormonal profile of all treatment groups of the buffalo heifers exhibited significant (P<0.05) variations as compared to the control group (G-1). These results indicate suppression in Nili-Ravi buffaloes' reproductive hormonal profile on exposure to P. multocida B:2 and its immunogens. This influence warrants that exposure to H.S may be a possible reason for delayed puberty and poor reproduction performance in Nili-Ravi buffaloes.
Levantamento de recursos e uma avaliação atual do Ensino de Astrofísica Estelar
Authors: Paulucci L. , Fornazari J. F. , Brasil Neves K. , Horvath J.E.
Published: January 2022

O conhecimento das estrelas avançou de maneira fundamental no último século, sendo que hoje podemos descrever os processos envolvidos em seu nascimento, evolução e morte. No entanto, a transposição do conhecimento científico estelar para a sala de aula não foi feita de maneira ampla ou tem sido feita em geral de forma fragmentada e parcial. Apresentamos aqui um levantamento sobre os trabalhos desenvolvidos nas últimas décadas para o ensino de Astrofísica Estelar (focado no material disponível em língua portuguesa) de modo a organizar e facilitar o trabalho da ampliação da abordagem deste tópico junto a estudantes, em particular no ensino básico, além de algumas sugestões de aplicações que poderão enriquecer o trabalho dos professores. Apresentamos também uma avaliação crítica do panorama dentro do ensino brasileiro.
Coping moderates the relationship between intolerance of uncertainty and stress in men during the Covid-19 pandemic
Authors: Palma Emanuel Missias Silva , Reis de Sousa Anderson , Andrade de Morais Franciane , Evangelista Luz Ramon , Freitas Neto Álvaro Lima , Lima Pâmela Pitágoras Freitas
Published: January 2022

Abstract Objective: To test the explanatory power of coping strategies and intolerance of uncertainty on men’s perceived stress levels and test the moderating role of coping strategies in the relationship between intolerance of uncertainty and perceived stress during the Covid-19 pandemic. Method: This was an online cross-sectional study in which 1,006 men living in Brazil during the Covid-19 pandemic participated. Participants were recruited using a snowball sampling technique and completed a questionnaire containing measures of all study variables. Data were examined using a correlation and a regression analysis. Results: Intolerance of uncertainty (β = .51) and refusal (β = .15) positively predicted perceived stress, whereas control (β = –.31) and isolation (β = –.06) negatively predicted it. Together, these variables explained 52% of men’s perceived stress (p < .001). Isolation and social support lessened the relationship between intolerance of uncertainty and stress (p < .001). Conclusion: Men high in intolerance of uncertainty and refusal were more vulnerable to stress during the pandemic. However, coping helped mitigate the relationship between intolerance of uncertainty and perceived stress, thus being a promising psychosocial intervention in this context.
Optimization of enzymatic hydrolysis of Pleurotus ostreatus derived proteins through RSM and evaluation of nutritional and functional qualities of mushroom protein hydrolysates
Authors: Goswami Bhaswati , Majumdar Sayari , Dutta Ruma , Bhowal Jayati
Published: January 2022

Abstract Pleurotus ostreatus (Jacq.) P. Kumm., the second most widely cultivated oyster mushroom was grown on paddy straw, which is cheap and readily available waste material. After harvesting and drying, nutritional, and antinutritional composition of P. ostreatus were estimated using the standard assay methods. Tannin and phytic acid were present in very negligible amount (0.095 ± 0.027 mg/g and 0.150 ± 0.083 mg/g, respectively), whereas oxalate and cyanide were absent in whole mushroom. In fact, P. ostreatus was hydrolysed with commercially available proteinase K, pepsin and trypsin with different concentrations of the enzymes (0.05%, 0.10% and 0.15%), at different temperatures (30 °C, 40 °C and 50 °C) for different time periods (60, 90 and 120 min) to get the mushroom protein hydrolysates. Degree of hydrolysis and protein content varied from 4.29 ± 1.12% to 99.42 ± 0.02% and from 0.25 ± 0.07 mg/mL to 3.22 ± 0.12 mg/mL, respectively. Maximum degree of hydrolysis and the highest protein content of protein hydrolysate was obtained when using 0.15% proteinase K, at 50 °C for 120 minutes. Mushroom protein hydrolysates thus obtained exhibited improved functional characteristics such as foaming capacity, foaming stability and emulsifying property than the unhydrolysed mushroom. Based on the result of the present study, the mushroom protein hydrolysates could be served as useful ingredient for food and nutraceutical applications.
Adolescentes grávidas que experienciaram o nascimento prematuro: percepções acerca do cuidado pré-natal
Authors: Marques Tatiane Montelatto , Marski Bruna de Souza Lima , Souza Bruna Felisberto de , Bonelli Maria Aparecida , Fabbro Marcia Regina Cangiani , Wernet Monika
Published: January 2022

Resumo Objetivo conhecer os significados atribuídos ao pré-natal por adolescentes que pariram prematuramente e seus alcances ao parto e nascimento. Método estudo qualitativo que adotou o Interacionismo Simbólico e a Análise de Conteúdo Temática como referenciais teóricos e metodológicos e a entrevista aberta como instrumento de coleta de dados. Onze adolescentes residentes em um município do interior paulista integraram o estudo ao longo do ano de 2018. Resultados as adolescentes apontaram relações limitadas com os profissionais com obstáculos ao desenvolvimento da autonomia para as questões da gestação, parto e nascimento, assim como para o estabelecimento do apoio social. Emergiram três categorias temáticas: ‘Início do pré-natal: reflexões e projeções futuras’; ‘Insuficiências na atenção pré-natal’ e ‘(Des) acolhimento no parto e nascimento’. Conclusão conhecer os significados atribuídos ao pré-natal por adolescentes que pariram prematuramente favoreceu apontamentos ao atitudinal do profissional em relação à consideração da adolescente enquanto indivíduo que direciona o cuidado por meio de seu lugar de fala e no exercício dos seus direitos no sentido de promover uma experiência positiva e qualificar o pré-natal.
Masking Level Difference: avaliação da confiabilidade teste-reteste em estudantes universitárias normo-ouvintes
Authors: Frota Silvana Maria Monte Coelho , Leite Filho Carlos Alberto , Bruno Carolina Salomone , Carvalho Lanna Borges , Riegel Natalia Almeida , Souza Sascha Ariel da Silva Rodrigues de , Branco-Barreiro Fátima Cristina Alves
Published: January 2022

RESUMO Objetivo Verificar a confiabilidade teste-reteste do Masking Level Difference em estudantes universitárias normo-ouvintes. Método Estudo prospectivo descritivo com 78 adultos jovens do gênero feminino sem queixas auditivas, submetidas à versão, em compact disc, do Masking Level Difference da Auditec of Saint Louis. O Masking Level Difference foi determinado por meio da diferença entre as relações sinal-ruído nos limiares auditivos encontrados nas condições antifásica e homofásica. O teste foi aplicado pelo mesmo examinador em dois momentos (teste e reteste) com intervalo de sete a 14 dias entre eles. A análise estatística inferencial incluiu comparação das situações teste e reteste por meio do teste t de Student para amostras pareadas, cálculo do coeficiente de correlação intraclasse e dos intervalos de confiança de 95% para as relações sinal/ruído nos limiares auditivos nas condições antifásica e homofásica e para o cálculo do Masking Level Difference. Resultados A média da relação sinal-ruído no limiar auditivo na condição homofásica foi -12,59 dB e -12,46 dB nas situações teste e reteste, respectivamente, e -21,54 dB e -21,08 dB na condição antifásica. A média do Masking Level Difference foi 8,95 dB no teste e 8,74 dB no reteste. Os coeficientes de correlação intraclasse obtidos foram 0,436, 0,625 e 0,577 para as condições homofásica, antifásica e Masking Level Difference, respectivamente. Conclusão O teste Masking Level Difference mostrou grau moderado de confiabilidade teste-reteste em estudantes universitárias normo-ouvintes.
Repercussão da implementação do Picture Exchange Communication System – PECS no índice de sobrecarga de mães de crianças com Transtorno do Espectro do Autismo
Authors: Ferreira Carine , Caetano Sheila Cavalcante , Perissinoto Jacy , Tamanaha Ana Carina
Published: January 2022

RESUMO Objetivo O objetivo deste estudo foi analisar a repercussão da implementação do PECS no índice de sobrecarga de mães de crianças com Transtorno do Espectro do Autismo (TEA). Método Trata-se de um estudo longitudinal (CEP 0403/2017). A amostra foi constituída por 20 díades mães-crianças com TEA. As mães tinham em média, 41 anos e 5 meses e as crianças, 7 anos e 2 meses. Quinze crianças eram do gênero masculino e cinco, do feminino. Foi aplicada a versão brasileira da escala Burden Interview cujo objetivo é a verificação do nível de sobrecarga dos cuidadores. Para análise dos comportamentos não-adaptativos aplicou-se o Autism Behavior Checklist (ABC) e para análise do repertório lexical: os Testes de Vocabulário Auditivo e Expressivo. O Programa de Implementação do PECS foi composto por 24 sessões de terapia fonoaudiológica individual com a presença ativa das mães. Ao final do Programa todas as crianças e suas respectivas mães foram reavaliadas com parte dos instrumentos utilizados na fase inicial do estudo. Resultados Houve tendência de redução dos índices de sobrecarga materna após a implementação do PECS. Notamos diminuição significativa dos comportamentos não-adaptativos e aumento dos índices de vocabulário expressivo e auditivo das crianças no momento final do estudo. Não observamos correlação significativa entre os índices de sobrecarga com a idade, escolaridade e quociente intelectual das crianças; nem com a escolaridade e nível socioeconômico materno. Conclusão Foi possível analisar a repercussão da implementação do PECS na sobrecarga de mães de crianças com TEA assistidas pelo Programa.
A tecnologia a favor da educação continuada no implante coclear
Authors: Magalhães Ana Tereza de Matos , Gomez Maria Valéria Schimdt Goffi , Tsuji Robinson Koji , Bento Ricardo Ferreira
Published: January 2022

RESUMO Objetivo avaliar a teleconsulta de forma síncrona no mapeamento do implante coclear (IC) como ferramenta de educação continuada para fonoaudiólogos em capacitação e treinamento. Métodos estudo prospectivo longitudinal, na modalidade de preceptorado clínico, com teleconsulta de forma síncrona direcionada ao atendimento de mapeamento dos usuários de IC. A educação continuada foi oferecida aos fonoaudiólogos aprimorandos em um hospital e o fonoaudiólogo tutor, em unidade remota. A plataforma utilizada permitiu ao tutor visualizar e realizar intervenções na tela de mapeamento do IC. Foram aplicados três questionários abrangendo os marcadores de ensino; qualidade e importância da teleconsulta; interação entre os profissionais e autoavaliação sobre a confiança na realização das etapas do mapeamento antes e após as teleconsultas. Resultados participaram sete fonoaudiólogos e foram analisados 268 atendimentos, ao longo de três anos. Os marcadores clínicos mostraram, na média e individualmente, que houve correlação estatística com diminuição do número de intervenções totais, nas intervenções do mapeamento do IC e raciocínio clínico, no decorrer das sessões. A média das notas nas avaliações da importância da teleconsulta foi 9,7 e a interação com o tutor, 9,3. Na autoavaliação, todos os aprimorandos responderam que estavam “nada/pouco confiantes” para as etapas do mapeamento antes da intervenção e, ao final do curso, responderam “moderadamente/muito confiantes” para as mesmas etapas. Conclusão o uso da teleconsulta síncrona foi viável e eficiente como ferramenta de ensino para fonoaudiólogos. Foi possível observar a diminuição do número de intervenções ao longo do tempo, evidenciando a curva de aprendizado.
Efeitos dos exercícios vocais no tratamento da disfagia: revisão integrativa
Authors: Queiroz Amanda Thaís Lima de , Barreto Fabíola Gonzaga , Santos Tuany Lourenço dos , Ximenes Coeli Regina , Gomes Adriana de Oliveira Camargo
Published: January 2022

RESUMO Objetivo verificar as evidências disponíveis sobre o efeito dos exercícios vocais no tratamento da disfagia. Estratégia de pesquisa foi realizado levantamento bibliográfico nas bases de dados PubMed, LILACS, SciELO e MEDLINE, sem restrições quanto ao período de publicação. Critérios de seleção artigos originais, estudos de caso e/ou revisões de literatura publicados nos idiomas português e/ou inglês, disponíveis eletronicamente na íntegra e que abordassem o tratamento clínico com exercícios vocais em adultos e idosos com disfagia. Foram excluídas publicações repetidas nas bases de dados, com população de crianças, com indivíduos que não apresentassem o diagnóstico de disfagia, com exercícios vocais sem especificação, com exercícios exclusivos de deglutição, artigos e/ou resumos sem possibilidade de acesso pelas plataformas institucionais e estudos com modelo animal. Resultados foram encontrados 2.356 artigos, dos quais, após aplicados os critérios de elegibilidade, foram selecionados 8 para a amostra final. Para avaliar os efeitos dos exercícios vocais, os estudos utilizaram avaliação clínica, videofluoroscopia, videoendoscopia e eletromiografia. Quanto aos efeitos dos exercícios vocais na deglutição, observou-se que as técnicas de som plosivo, empuxo, trato vocal semiocluído, som basal, modulação vocal, sobrearticulação, o método Lee Silverman Voice Treatment® e o uso de exercícios de treino de força muscular expiratória apresentaram efeitos positivos na reabilitação da disfagia. Conclusão os estudos com treino de força muscular expiratória, o método Lee Silverman e os exercícios vocais tradicionais demonstraram efeitos positivos no tratamento da disfagia. No entanto, ainda não foi possível comprovar o nível de evidências de todos os estudos.
Classificação da participação de crianças em ocupações nos contextos escolares na perspectiva da terapia ocupacional
Authors: Folha Débora Ribeiro da Silva Campos , Barba Patrícia Carla de Souza Della
Published: January 2022

Resumo A Educação Infantil é caracterizada por ocupações relacionadas ao brincar, ao autocuidado e à aprendizagem. Para a terapia ocupacional, a participação nessas ocupações reflete no desenvolvimento físico, cognitivo, social, afetivo e ocupacional das crianças. Este estudo objetivou analisar formas de participação infantil em ocupações nos contextos escolares e propor critérios para classificação dessa participação, na perspectiva da terapia ocupacional. Foi realizada uma pesquisa qualitativa, de observação participante a partir da técnica das Descrições Narrativas. Participaram deste estudo quatro crianças com desenvolvimento típico (DT) e quatro crianças que faziam parte do Público-Alvo da Educação Especial (PAEE), sendo uma com deficiência física e três com Transtorno do Espectro Autista (TEA). Para a análise dos dados, a técnica de Análise do Conteúdo fez emergir quatro formas de participação, a partir de elementos como envolvimento na ocupação, assistência necessária ou autonomia na participação, tolerância, interações sociais, motivação e iniciativa. Essas formas de participação foram denominadas de participação plena, participação ativa assistida, participação rudimentar e participação restrita. A participação plena foi preponderante manifestada pelas crianças DT e a participação ativa assistida esteve relacionada à criança PAEE com deficiência física. Já a participação rudimentar e a participação restrita foram evidenciadas exclusivamente por crianças PAEE com TEA. Consideram-se os resultados relevantes para a identificação precoce de facilitadores e barreiras para a participação, bem como para o adequado provimento de condições e intervenções que potencializem a participação de todas as crianças nos ambientes escolares e para o fortalecimento e ampliação da atuação dos terapeutas ocupacionais nestes.
Revisão externa das Diretrizes da SBC segundo a ferramenta AGREE II - Precisamos rever nossas Diretrizes?
Authors: Luna Leonardo Castro , Magliano Carlos Alberto , Dos Santos Renata Medina , De Almeida Breno Macedo , Fatorelli Antonio , Barata Renata de Souza , De Andrade Leandro Calixto , Maiolino Paula Aguieiras , Santos Marisa , Pereira Rafhael , De Albuquerque Thiago Derminio Cavalcanti , Ribeiro Jéssica
Published: January 2022

INTRODUÇÃO: Diretrizes Clínicas devem ser documentos elaborados de forma sistemática que visam em primeiro lugar apoiar com a melhor informação médica disponível a decisão de um paciente e de um profissional de saúde. Adicionalmente também podem ser utilizadas pelo gestor para a formulação de políticas públicas. OBJETIVO: Avaliar a qualidade metodológica de 3 Diretrizes Clínicas da Sociedade Brasileira de Cardiologia (SBC) segundo uma ferramenta aceita internacionalmente para esta finalidade, e sugerir melhorias na elaboração deste tipo de documento. MÉTODOS: 12 avaliadores independentes (4 por documento) utilizaram a ferramenta AGREE II para avaliar metodologicamente três Diretrizes Clínicas da SBC que abordam assuntos de extrema importância e prevalência na população mundial: Hipertensão Arterial, Diabetes e Dislipidemia. RESULTADOS: Segundo a avaliação das 3 Diretrizes, pelos baixos escores recebidos principalmente nos domínios de Envolvimento das Partes Interessadas, Aplicabilidade da Diretriz e em especial no Rigor do Desenvolvimento, 2 delas foram consideradas com uma metodologia de elaboração insatisfatória. CONCLUSÃO: A qualidade metodológica das Diretrizes Clínicas da SBC foi considerada insatisfatória. Sugerimos neste artigo estratégias para aprimorar o processo de elaboração de futuros documentos.
TPRG1 contributes to inflammation and cell proliferation of cystitis glandularis through regulating NF-кB/COX2/PGE2 axis
Authors: Hong Tao , Piao Songzhe , Sun Liangxue , Tao Yiran , Ke Mang
Published: January 2022

Cystitis glandularis is characterized by chronic inflammation and hyperproliferation of bladder mucosa, and contributes to progression of bladder adenocarcinoma. TPRG1 (Tumor Protein P63 Regulated 1) is related to cellular inﬂammatory response, and dysregulation of TPRG1 in tumor tissues is associated with tumor early recurrence. The effect of TPRG1 on cystitis glandularis was investigated in this study. Firstly, bladder specimen were isolated from patients with cystitis glandularis and E. coli-induced cystitis rat. Expression of TPRG1 was found to be up-regulated in the bladder specimen. Moreover, adeno-associated virus (AAV)-mediated silence of TPRG1 was delivered into rat, and data from hematoxylin and eosin (H & E) staining showed that injection with AAV-shTPRG1 ameliorated E. coli-induced histological changes in bladder tissues of rats, and suppressed the inflammatory response. Secondly, TPRG1 was also increased in primary cystitis glandularis cells. Knockdown of TPRG1 decreased cell proliferation of primary cystitis glandularis cells, and suppressed the migration. Thirdly, cyclooxygenase-2 (COX-2) was up-regulated in the bladder specimen isolated from patients with cystitis glandularis and E. coli-induced cystitis rat. Injection with AAV-shTPRG1 reduced protein expression of COX-2, p65 and prostaglandin E2 (PGE2) in the bladder specimen. Lastly, interference of COX-2 attenuated TPRG1 over-expression-induced increase of cell proliferation and migration in the primary cystitis glandularis cells. In conclusion, TPRG1 promoted inflammation and cell proliferation of cystitis glandularis through activation of NF-кB/COX2/PGE2 axis.
Participation, trust, and risks associated with peer-to-peer accommodation platforms : How did the COVID-19 crisis affect Airbnb Budapest in 2020?
Authors: Simonovits Bori , Zách Boglárka , Kondorosy Csenge
Published: January 2022

Our research was aimed at exploring the different layers of trust with regard to Airbnb services, as well as the practices of discrimination on the platform. The fieldwork was carried out in the first half of 2020, partly before and partly after the COVID-19 related interventions, which significantly affected life in Budapest from mid-March 2020 onwards. A total of 21 semi-structured interviews were carried out, supplemented with online discourse analysis. Our empirical analysis revealed that most of our interviewees displayed positive attitudes towards Airbnb, but our online discourse analysis showed that there are rather mixed attitudes towards the company. Considering the platform from an employment perspective, certain elements of precarious working conditions were identified. When it comes to different layers of trust, we point out that interpersonal trust between guests and hosts is crucial, resulting in positive experiences for hosts in many ways. We found social trust in Airbnb to be more ambiguous, as some interviewees claimed to have concerns with regard to its effect on the housing market. Finally, distributed trust on the platform seemed significant, as ratings often serve as a means of predicting guests’ trustworthiness. Most of the hosts we interviewed were aware of the fact that discrimination is not tolerated at all by the platform, so it is not surprising that we could hardly identify any cases of overt discrimination; however, latent forms of discrimination and negative attitudes as well as stereotypes that were formed by the hosts in relation to numerous nationalities and minorities were explored in our empirical research.
SARS-CoV-2 NCBI consensus submission protocol: GenBank v3
Authors: Timme Ruth , Griffiths Emma , Katz Lee , MacCannell Duncan , Weigand Michael
Published: January 2022

This is a SARS-CoV-2 specific protocol that covers the steps needed to submit SARS-CoV-2 consensus sequence to GenBank. If you need a pipeline for frequent or large volume submissions, follow Step 1 in the SARS-CoV-2 NCBI submission protocol: SRA, BioSample, and BioProject to get your NCBI submission environment established, then contact gb-admin@ncbi.nlm.nih.gov to set up an account for submitting through the API. This protocol assumes (and requires) that the user has a BioProject and BioSamples(s) already registered. Complete in order:: 1. Populate your templates first. 2. SARS-CoV-2 NCBI submission protocol: SRA, BioSample, and BioProject Step-by-step instructions for establishing a new NCBI laboratory submission account and for creating and linking a new BioProject to an existing umbrella effort. SARS-CoV-2 raw data submission to SRA (Sequence Read Archive) and metadata to BioSample. Users can modify this protocol to just create a BioSample with no linked raw data. 3. SARS-CoV-2 NCBI consensus submission protocol: GenBank (included protocol) Required: established BioProject and BioSamples Submit SARS-CoV-2 assemblies to NCBI GenBank, linking to existing BioProject, BioSamples, and raw data. Version history: V3: Direct links provided to download metadata templates (instead of hosting duplicate files). minor edits throughout the protocol.
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Bogus Data Acquisition Protocol I v1
Authors: Moore Abby
Published: January 2022

The purpose of this protocol is to demo protocol development. The real version of this protocol might be developed with respect to existing publications. Here, I'll refer to publications using the Citation component.
Bogus Data Acquisition Protocol III v1
Authors: Moore Abby
Published: January 2022

The purpose of this protocol is to demo protocol development.
Bogus Data Acquisition Protocol IV v1
Authors: Moore Abby
Published: January 2022

The purpose of this protocol is to demo protocol development.
Blurring Boundaries Between Journalists and Tiktokers: Journalistic Role Performance on TikTok
Authors: Negreira-Rey María-Cruz , Vázquez-Herrero Jorge , López-García Xosé
Published: January 2022

In recent years, media has adapted to the logic of each new social network to respond to renewed consumption habits and journalists have developed new roles on these platforms. TikTok is an emerging platform with its own influencer culture and in which the main audiences are the millennial and centennial generations. The main objective of this study is to analyze the presence of journalists on TikTok through the type of content and strategies used in adapting to this platform. The research is based on methodological triangulation. First, a database of journalists on TikTok (n1 = 212) was developed and the profiles were reviewed. Second, a questionnaire survey (n2 = 63) was developed. Finally, a content analysis (n3 = 520) of profiles exceeding 100,000 followers was conducted. This research provides a first description of the activity of journalists on TikTok, where a variety of roles, usages, and strategies are identified, beyond those of their profession. They join the of-the-moment platform with different purposes (to inform, entertain, or introduce themselves) and targets (new audiences, young people, fans). Journalists adapt their presence to the TikTok social media logic, seeking a space of influence on a platform that is the natural habitat of younger generations.
Disruptive Technology in Digital Notice Board using Flutter
Authors: Sanger Anirudh Singh , Prasad Tanmay , Singh Yashwant , Jha Rahul , Rao Sandeep , Sharma Vaibhav , Mukhija Dr. Manish
Published: January 2022

In early days, notice boards were used to place notices which is a very hard process. First a teacher has to make a notice on his computer and edit to make it attractive then he must get it approved by the HOD. Then when it gets approved, he must print it then the teacher must go to every notice board and physically pin the notice on the notice board Which is a very hard and time-consuming process. In order to make this experience easy we are proposing a digital notice board Which will make the process very easy and very efficient. Our main aim is to make information easy to access to students and at the same time make it easy for teachers to build a notice using their phones and the templates provided on the app.
Intelligent Speed Regulation Control of Switched Reluctance Motor of Electric Vehicle Based on Neural Network Parameter Identification
Authors: Xiaoliang Zhang
Published: January 2022

Based on the analysis of the related theories of switched reluctance motor, this paper designs and implements the intelligent speed regulation system of switched reluctance motor for electric vehicle. The speed regulation system has the characteristics of high efficiency and energy saving, wide speed regulation range and small starting current. The system also has the advantages of large starting torque, frequent start and stop, forward and reverse switching, high torque / inertia ratio and four quadrant operation. The system can provide a good solution for variable speed drive. The digital controller of the system is composed of TMS320F2812 DSP and EPM7128S CPLD, which can realize the starting, electric and braking functions of electric vehicles. Experiments show that the switched reluctance motor drive system for electric vehicle has good control performance and strong fault tolerance. The system can meet the requirements of various working conditions of electric vehicles and has broad development prospects.
Application of Network Security Event Correlation Analysis and Situation Evaluation Technology
Authors: Yu Qing
Published: January 2022

Network security situational awareness can integrate all aspects of network security elements. Through correlation analysis, information fusion, situation prediction and other technologies to realize the intelligent analysis and comprehensive decision-making of complex information systems, network security situation awareness can improve the management efficiency and effect of complex networks. In order to solve the problem of parameter optimization of existing situation assessment methods, the parameters of SVM model are optimized based on Particle Swarm Optimization PSO algorithm. This paper presents a network security situation assessment method based on PSO and SVM. Using this algorithm can get a better balance between time-consuming and improving accuracy. At the same time, the index weight is determined according to grey correlation analysis, and the training samples are input to support vector machine for training. In this paper, the improved particle swarm optimization algorithm is used to optimize the parameters of support vector machine to improve the effect of situation assessment. Simulation test results show that the evaluation method improves the effectiveness and accuracy of situation assessment.
BIM Technology Application Strategy in the Whole Life Cycle of Green Building
Authors: Huang Bo
Published: January 2022

This paper summarizes the concept, influencing factors, principles and design methods of green building by combing the relevant research of green building at home and abroad. On this basis, this paper takes the whole life cycle practice process as the main line, and puts forward the specific application strategy of corresponding BIM Technology for the bottleneck problem of traditional technology in each stage. Then this paper demonstrates the unique advantages and feasibility of BIM Technology through practical cases. Among them, BIM Technology integrates geometric model and attribute database, and realizes the organic combination of spatial data and attribute data. The test results show that the BIM calculation and analysis function and ecological condition simulation function provide a very effective performance analysis tool and auxiliary decision-making tool for green building project participants. This paper studies the relationship between green building, life cycle and BIM, and puts forward constructive BIM application strategies, hoping to provide scientific reference for green building practice and related research, so as to achieve the goal of healthy and sustainable development of construction industry.
The New "offline + Online" Teaching Model of College English Based on Cloud Computing
Authors: Liu Peng
Published: January 2022

Through literature review, this paper expounds the descriptive parameter framework of College English mixed teaching and the index framework of teachers' effective teaching behavior in College English mixed teaching and its influencing factors. Based on this, this paper studies the new "offline + online" teaching model of College English based on cloud computing. This paper verifies and enriches the framework established based on literature through pilot interviews. For the part of effective teaching behavior, this paper applies Delphi expert survey method to conduct two rounds of questionnaire consultation with 10 information-based foreign language teaching research experts, and forms the final effective teaching behavior questionnaire. The results of this study show that teachers' effective teaching behavior in College English teaching can be summarized into five factors. According to the explanatory power, the order from high to low is: online learning management, teacher support, organizing face-to-face classroom, diversified evaluation and personalized teaching. Therefore, the new "offline + online" teaching model of College English based on cloud computing can improve the efficiency of English teaching.
Bilateral Symmetry of Number and Size of Dental Caries Lesions among Children
Authors: Dagon Nurit , Blumer Sigalit , Liani Devora , Peretz Benjamin , Ratson Tal
Published: January 2022

Aim. To determine the bilateral occurrence of caries lesions in 5–12-year-old children, and to assess whether one bitewing photograph can predict caries size and occurrence in the homologous tooth on the other side of the mouth.

Study design. The study was carried out on 222 medical files of children 5–12 years old who were first examined in the university dental clinic. The presence and size of the caries lesions in the first and second primary molars and first permanent molars were recorded.

Results. No correlation was found when comparing the caries lesion distribution of each tooth’s proximal surface. Seventy-one of the X-rays demonstrated a single caries lesion in a first or second primary molar or in a first permanent molar on one side of the mouth, of which 21.3% demonstrated a single caries lesion in the collateral side, 43.6% demonstrated 2 or more lesions, and 35.21% did not have any caries lesion on the collateral side of the mouth.

Conclusion. One bitewing cannot determine the presence and size of a caries lesion on the same site of the homologous tooth.
Immersive and Non-Immersive Virtual Reality Distraction on Pain Perception to Intraoral Injections
Authors: Kumari Supriya , Bahuguna Rachana , Garg Nishita , Yeluri Ramakrishna
Published: January 2022

Objective: To evaluate the efficacy of immersive VR (IVR) and non-immersive VR (NIVR) distraction on perceived pain during intraoral injections in children undergoing dental procedures. The objective was to introduce 3-dimensional nature of virtual reality during the provoking phase of dental treatment as a means of distraction in children.

Study design: A total of 200 children were selected for the study, 100 for IVR group and 100 for NIVR group. After randomization, children were introduced to Oculus Go Standalone equipment; MCDAS (f), VAS, WBFRS and the treatment procedure using tell show do technique. Group I children were introduced to oculus go standalone headset with hand held controller to play temple run or roller coaster game while in group II, children watched cartoon movies of their choice. Pre-operative & post-operative MCDAS scores were obtained using MCDAS (f) questionnaire in local language. Post-operatively, VAS and WBFRS scores were also obtained. The data was analyzed using independent t-test and chi-square analysis.

Results: Pre-operatively, the mean MCDAS scores were similar in both the groups viz. Group–I (29.20 ± 3.197) and Group–II (29.09 ± 3.803) and is statistically not significant. Post-operatively, the mean MCDAS scores were higher in non-immersive group (20.72 ± 2.822) as compared to immersive group (10.99 ± 2.227). VAS score was higher in non-immersive group (2.72 ± 0.99) as compared to immersive group (0.75 ± 0.88). WBFRS scores were higher in non-immersive group (2.78 ± 1.097) as compared to immersive group (0.82 ± 1.104).

Conclusion: Three-dimensional virtual reality was found to be an effective means of distraction in children undergoing dental procedures and especially during the provoking phase. The significant difference obtained clearly indicates irrespective of immersiveness of virtual reality, anxiety had been decreased and on comparison the pain perception to intraoral injection is less in immersive virtual reality environment. Immersive VR distraction technique can serve as an adjunct to traditional behavior management strategies already available to the pediatric dentist.
Rancang Bangun Alat Pemipih Emping Melinjo (Gnetum gnemon) Tipe Mekanis
Authors: Dhafir Muhammad , Zulfahrizal Zulfahrizal , Fadhil Rahmat , Safrizal Safrizal , Mutiawati Mutiawati
Published: January 2022

Abstrak. Pengolahan biji melinjo menjadi emping melinjo saat ini sebagian besar masih menggunakan cara tradisional (manual) yaitu dengan memukul-mukul biji melinjo menggunakan palu yang sebelumnya sudah disangrai dengan pasir. Teknik ini dirasakan tidak efektif karena memerlukan waktu yang cukup lama dan tenaga manusia yang besar. Untuk mengatasi masalah tersebut perlu dibuat suatu mesin untuk memudahkan dalam pemipihan biji melinjo. Penelitian ini bertujuan untuk desain mesin pemipih emping melinjo dengan sumber tenaga motor listrik,  menguji fungsional dan kinerja mesin serta membandingkannya dengan  metode tradisional. Parameter yang diamati meliputi kapasitas kerja mesin serta persentase kehilangan hasil. Hasil penelitian diperoleh bahwa mesin pemipih emping melinjo tipe tumbukan mempunyai ukuran panjang 820 mm, lebar 520 mm dan tinggi 1010 mm, digerakkan dengan motor listrik dengan daya 1.5 hp 1450 rpm. Hasil pengujian mesin didapatkan kapasitas pemipihan 0.83 kg/jam sedangkan kapasitas secara manual 0.16 kg/jam. Persentase kehilangan hasil dari pemakaian mesin pemipih emping ini adalah 1.5 %  sedangkan dengan cara manual adanya kehilangan hasil yaitu sebesar 7 %.  Design and Performance Test Of Flatter Machines  Impact Type for Melinjo (Gnetum gnemon)Abstract. Flatteting of melinjo seeds into melinjo chips at this time most still use the manual method by beating the seeds of melinjo using a hammer that was previously roasted with sand. This technique is felt to be ineffective because it requires a long time and a large amount of human energy. To overcome these problems, a solution is needed to facilitate flattening the seeds of melinjo. This study aims to design melinjo chips flattening machine with an electric motor as a power source, to test the functionality and performance of the machine, and to compare it with traditional methods. The parameters observed include the machine's working capacity and the percentage of yield loss. The results showed that this flatter machines impact type for melinjo has a length of 820 mm, the width of 520 mm, and a height of 1010 mm, driven by an electric motor with a power of 1.5 HP with a rotation of 1450 rpm. The results of testing the device obtained a flaking capacity of 0.83 kg/hour while the capacity manually was 0.16 kg/hour. The percentage of loss of results from the use of this emping flask is 1.5% while by manual the loss of results is equal to 7%.
Pengukuran Suhu Permukaan Menggunakan Pancaran Spektral dari Citra Satelit: Studi Kasus di Banda Aceh
Authors: Taqwallah Putra Arafat , Ramli Ichwana , Rizkia Alia
Published: January 2022

Abstrak. Tingginya tingkat urbanisasi menyebabkan meluasnya wilayah perkotaan dan menciptakan daerah keras yang mengakibatkan suhu tinggi di wilayah perkotaan, termasuk Banda Aceh. Permasalahan ini tentu menimbulkan ketidaknyamanan bagi masyarakat Banda Aceh. Beberapa penelitian melaporkan bahwa suhu udara yang terlalu tinggi dapat menyebabkan masalah kesehatan yang serius di masyarakat. Suhu permukaan Banda Aceh diukur menggunakan Spectral Radiance dari Satellite Imager, kemudian dibandingkan dengan data yang diukur langsung di lokasi penelitian. Hasil menunjukkan suhu udara di Banda Aceh berkisar antara 22,32°C hingga 34,86°C.  Selain itu, terjadi korelasi antara penggunaan ruang dengan tingkat suhu udara Banda Aceh berdasarkan parameter hard area dan vegetasi. Namun, hanya variabel jarak dengan badan air yang memiliki korelasi signifikan terhadap perubahan tingkat suhu.Surface Temperature Distribution Using Spectral Radiance from Satellite Imagery: A Case Study in Banda AcehAbstract. The high rate of urbanization will have an effect on land change. The increasing number of buildings and lack of green open space will hinder the direction of wind speed, cause inconvenience to the public. The purpose of this study was to determine the distribution of surface temperature in the city of Banda Aceh based on the spectral emission of Landsat images from vegetation density, distance from the river, and built-up area. The air temperature data were obtained using the classification method from the digital number value of the Landsat image to the spectral radiance and then converted into air temperature. The density of the built-up area was analyzed from the Normalized Difference Vegetation Index (NDBI) and the density of the vegetation was analyzed from the Normalized Difference Vegetation Index (NDVI). The air temperature distribution map from the image is divided into 3 zones that are densely populated (built-up area), vegetation and distance to water bodies to be measured directly in the field. The air temperature from the lansat 8 images ranged from 22.32°C to 34.86°C. The zone with a distance of 3,457 km from a water body, with less vegetation density (0) and a built-up area of 0.16-0.23 has a temperature of 31.96oC -32.45oC, while the zone with a water body distance of 1,255 km with a built-up area below zero and vegetation has a temperature of 25.82oC-27.09oC. Based on the parameters of space use (vegetation and built-up area) and the distance between the zone and the water body, it has an influence on the distribution of air temperature in the city of Banda Aceh.