bluuebunny/crossref_metadata_2025 huggingface dataset:
Strategic alignment between supply chain partners and cost stickiness of suppliers
Authors: Chiang Chia-Hsin , Choy Helen , Yang Yan-Jie , Yeh Shu-Ling
Published: July 2024

We investigate the relationship between strategic alignment between suppliers and their major customers and the asymmetric behavior of costs, specifically cost of goods sold (COGS) and selling, general, and administrative (SG&A) costs. Utilizing mandated disclosures regarding major customers from 1978 to 2018, we construct supplier–customer dyads to examine this connection. Our results indicate a positive association between strategic alignment in supply chain partnerships and the stickiness of COGS and SG&A costs for suppliers. This positive association is more pronounced for suppliers in the early stages of their relationships than those with long-term partnerships. Additionally, strategic alignment increases the stickiness of suppliers’ research and development (R&D) costs. Furthermore, we observe that strategic alignment correlates with an extended duration of supplier–customer relationships and improved supplier performance. Our findings hold across alternative constructs of strategic alignment, various supplier strategy types, and when accounting for characteristics of the supply-chain relationship.
Understanding solidarity in the European Union: an analytical framework
Authors: Saracino Daniele
Published: July 2024

Solidarity is a key concept in the European Union. However, the concept of solidarity lacks systematic theoretical examination to enable a sufficient understanding of its contextual meaning and to provide an operationalisable benchmark for analysis. To address this research gap, I propose an analytical framework for solidarity in the European Union that features four necessary conditions: particularity, instrumentality, reciprocity, and responsibility. I develop the framework through a transdisciplinary conceptual history approach, substantiated with a thorough document and legal analysis of European integration and CJEU case law. I demonstrate the robustness and validity of the proposed framework by using EU asylum policy as a test case, a field where the question of solidarity is notoriously salient, which is exemplified by an area-specific expression of the concept: fair sharing of responsibility between the EU member states. Moreover, I show that the EU’s solidarity principle is necessary to maintain the bloc’s raison d’être.
Exploring the association between growth mindsets and climate action with young people
Authors: Rissanen Inkeri , Kuusisto Elina , Aarnio-Linnanvuori Essi , Portus Rosamund , Williams Sara-Jayne , Laggan Sophie , Reilly Kathy , Vainikainen Mari-Pauliina
Published: July 2024

Decades of research has demonstrated the power of growth mindsets (i.e. belief in the malleability of the qualities of humans) to shape people’s ways of making sense of their socio-cultural reality and influence their ways of thinking about and acting towards change. Yet, research which connects mindsets with climate action or sustainability behavior remains scarce. This study explores the association between mindsets and climate action among European young people. Our findings, based on statistical analyses of survey data from Tampere (Finland), Genoa (Italy), Galway (Ireland) and Bristol (United Kingdom) (N = 1,814), indicate that growth mindsets about persons and groups are associated with some dimensions of climate action.1 However, the results also showed that the dimensions of climate actions are understood in slightly different ways in different countries, possibly because of contextual differences. Developing and researching locally adapted approaches to cultivate growth mindsets in climate change education is recommended.
Assessing the Performance of TOR Lubricants in Humid Environments and Under Dew Conditions
Authors: Skurka Simon , Galas Radovan , Omasta Milan , Ding Haohao , Wang Wen-Jian , Krupka Ivan , Hartl Martin
Published: July 2024

Top-of-rail (TOR) lubricants are commonly used for friction control in railway operations. They aim to lower friction and reduce noise and wear while ensuring sufficient transmission of traction/braking forces. However, the wheel–rail interface is an open system, so the conditions may suddenly change due to the weather, and different contaminants may enter the contact and influence the performance of these lubricants. Thus, this study examined the effect of humidity and dew on two commercial products, as these conditions often occur on the track. A methodology based on a creep curves measurement approach was used to assess product performance under various scenarios. All measurements were conducted on a universal tribometer in the ball-on-disc configuration covered with a climate chamber. The results show a strong influence of dew on the tested products, as dew lowered their performance parameters and caused low adhesion problems. Possible mechanisms of water–oil interaction and formation of oxidic third body layers were discussed. The main findings indicate that TOR lubricants may cause traction/braking problems if used in dew conditions. The present study may be helpful in optimising friction management methods in the future.

Graphical Abstract
Early Detection and Management of Lamanema chavezi infection in a llama (Lama glama) in Switzerland
Authors: Gliga Diana S. , Kramer Anne , Moré Gastón , Frey Caroline F. , Basso Walter
Published: July 2024

Lamanema chavezi is an entero-hepatic strongylid parasite specific to South American camelids. It has been reported only on few occasions outside South America. Due to its hepatic migration, it can cause extensive liver damage, leading to granulomatous and fibrotic hepatitis and manifesting with lethargy, anorexia, and even death. We are reporting the second case of L. chavezi infection in Europe and the first in Switzerland. The patient was a three-year old neutered male llama (Lama glama). Clinical examination revealed bloody mucous discharge from the anus. Fecal sedimentation/flotation revealed strongylid eggs consistent with L. chavezi, which were molecularly confirmed by a PCR targeting the ITS2 plus 5.8S and 28S rDNA flanking regions and amplicon sequencing. Eighteen weeks after administration of a single dose of eprinomectin (0.2 mg/kg i.m.), no further L. chavezi eggs were detected in the feces. The source of infection could not be traced back. The entire herd consisted of llamas bred in Switzerland. L. chavezi has been rarely reported outside South America, but its potential for pathogenicity and establishment should not be underestimated. Fecal sedimentation/flotation techniques should be routinely performed to ensure early detection of the parasite.
Influence of Sphagnum harvesting on arthropod fauna and vegetation with a focus on beetles (Coleoptera) and ants (Hymenoptera: Formicidae)
Authors: Zoch Lotta , Reich Michael
Published: July 2024

The harvesting of living peat moss (Sphagnum spec.) for various industrial applications has become increasingly prevalent. The harvesting process involves manual or mechanical extraction of Sphagnum fragments with minor to significant alterations of the habitats. This study investigates the impact of Sphagnum harvesting on arthropod fauna and vegetation structure at two donor sites with small-scale Sphagnum harvest in northwestern Germany. In the first year after the harvest, comparative surveys were carried out between harvested and unharvested reference areas. Arthropods living in and on the upper Sphagnum layer were studied by manually extracting quadrat samples. Vegetation surveys focused on the vascular plant composition and Sphagnum layer thickness as key habitat parameters. Results indicate no substantial effects on the total numbers for most arthropod orders. In contrast, the frequency of ant workers and the number of ant nests were considerably lower in harvested areas compared to reference areas. Vegetation analysis revealed that the shortening of the Sphagnum hummocks led to a homogenization of the vegetation structure and alterations in species composition in favor of moisture-loving species. Although no significant effects on total beetle populations were observed, the abundance of bog generalists and specialists was significantly reduced in harvest areas. Certain species displayed preferences for harvested or reference areas. Future harvesting practices should consider preserving vulnerable arthropod species and restricting harvesting to a small scale to mitigate adverse effects on bog ecosystems.
Modeling honeybee flower visitation rates in the fragmented agricultural landscapes based on Lévy-flight behavior
Authors: Rahimi Ehsan , Jung Chuleui
Published: July 2024

Typically, honeybees (Apis mellifera L.), rely on waggle dances performed by scout bees to communicate information about fruitful nectar and pollen sources across the landscape. However, when this communication is absent, inaccurate, or when resources become depleted, bees resort to alternative search strategies. Field experiments utilizing harmonic radar have revealed that honeybees follow flight patterns that demonstrate a scale-free (Lévy-flight) behavior, representing an optimal search strategy for relocating the original feeder location. If honeybees adhere to a Lévy flight pattern to discover resources, where would honeybees demonstrate the highest flower visitation rates in agricultural landscapes? We generated simulated landscapes with varying proportions of forest cover scenarios, ranging from 5 to 50% of the total landscape area, along with different levels of fragmentation per se. Subsequently, we constrained the richness of flower farm cells in each landscape. To predict honeybee visitation rates, three different methodologies based on random movement were utilized: (1) moving window, (2) random walk, and (3) Lévy flight. We found that honeybee visitation rates were influenced by the degree of forest fragmentation in each scenario. Across all visitation scenarios, the highest average number of visited flowers per cell was observed in landscapes with maximum fragmentation per se. In landscapes with lower forest cover and higher fragmentation, honeybees were more likely to visit a greater number of flowers due to the increased probability of traversing the landscape and encountering more flower cells. honeybee visitation rates in agricultural landscapes are significantly influenced by the degree of forest fragmentation. The study highlights the importance of considering landscape structure, specifically forest fragmentation, when predicting honeybee visitation rates and underscores the need for further research to better understand the intricate relationship between landscape characteristics and pollinator behavior.
Uni/multi variate polynomial embeddings for zkSNARKs
Authors: Gong Guang
Published: July 2024

A zero-knowledge proof is a cryptographic primitive that enables a prover to convince a verifier the validity of a mathematical statement (an NP statement) without revealing any secret inputs to the verifier. A special case, called zero-knowledge Succinct Non-interactive ARgument of Knowledge (zkSNARK) is particularly designed for arithmetic circuit proof systems which have important applications in blockchain privacy. The major computations in this type of zkSNARK proofs with post-quantum security are polynomial evaluations and Lagrange interpolations over finite fields. Given a sequence over a finite field, in the field of coding and sequences research, we understand that there are two representations of the sequence, one is a univariate polynomial and the other, a multivariate polynomial. This is exactly what is done in those zero-knowledge proof systems to transform the proof of a R1CS relation to evaluate uni/multi variate polynomials at some random points in the finite field. In this paper, we present a comparative analysis on how to convert a rank 1 constrained satisfiability (R1CS) system (more general than a circuit system) into a polynomial equality and provide analysis on the concrete complexities of provers, proof sizes and verifiers. We use two concrete zkSNARK schemes, i.e., Polaris, univariate polynomial encodings and Spartan, multivariate polynomial encodings, as examples to show our analysis. Secondly, we propose to select interpolating sets as subfields instead of affine spaces of a large field for Lagrange interpolation. This new method has improved the performance of R1CS encodings largely. We comment that post-quantum secure zkSNARKs yield post-quantum digital signatures with security only depending on symmetric-key schemes. Some open problems are proposed at the end of the paper.
Dielectric size optimization for high power density in large-scale triboelectric nanogenerators
Authors: Karabiber Abdulkerim , Dirik Ömer , Koc Feyyaz , Ozel Faruk
Published: July 2024

Triboelectric nanogenerators (TENGs) have emerged as a promising technology to harvest electrical energy from natural motions such as human movement, wind, and water flow. Although TENGs show significant potential in small-scale applications, developing large-scale TENGs capable of generating high power remains a significant challenge. Several factors that can affect the performance of large-scale TENGs are being investigated to overcome this challenge, including the size and configuration of dielectric materials. This study optimizes dielectrics regarding surface area, thickness, and multicell configuration to improve harvested electrical power density in large-scale TENGs. In the studies, glass fiber was used as the positive dielectric, and multipurpose white silicone was used as the negative dielectric because of their high tribo-potential, durability, and easy accessibility. In the size optimization phase, dielectric thicknesses and surface areas that provide the maximum power density were determined. Subsequently, horizontal and vertical multicell configurations were examined to efficiently integrate size-optimized dielectrics. The results reveal that large-scale TENGs with vertical multicell configurations can achieve high and usable energy density for electronics. The findings provide valuable insight into the development of large-scale TENGs with advanced power generation capabilities.
Construction and assessment of an angiogenesis-related gene signature for prognosis of head and neck squamous cell carcinoma
Authors: Wang Kaiqin , Zhang Ruizhe , Li Changya , Chen Huarong , Lu Jiafeng , Zhao Houyu , Zhuo Xianlu
Published: July 2024

Objective

Angiogenesis-associated genes (AAGs) play a critical role in cancer patient survival. However, there are insufficient reports on the prognostic value of AAGs in head and neck squamous cell carcinoma (HNSC). Therefore, this study aimed to investigate the correlation between AAG expression levels and survival in HNSC patients, explore the predictive value of signature genes and lay the groundwork for future in-depth research.

Methods

Relevant data for HNSC were obtained from the databases. AAGs-associated signature genes linked to prognosis were screened to construct a predictive model. Further analysis was conducted to determine the functional correlation of the signature genes.

Results

The signature genes (STC1, SERPINA5, APP, OLR1, and PDGFA) were used to construct prognostic models. Patients were divided into high-risk and low-risk groups based on the calculated risk scores. Survival analysis showed that patients in the high-risk group had a significantly lower overall survival than those in the low-risk group (P < 0.05). Therefore, this prognostic model was an independent prognostic factor for predicting HNSC. In addition, patients in the low-risk group were more sensitive to multiple anti-cancer drugs. Functional correlation analysis showed a good correlation between the characteristic genes and HNSC metastasis, invasion, and angiogenesis.

Conclusion

This study established a new prognostic model for AAGs and may guide the selection of therapeutic agents for HNSC. These genes have important functions in the tumor microenvironment; it also provides a valuable resource for the future clinical trials investigating the relationship between HNSC and AAGs.
Clinical and structural insights into the rare but oncogenic HER2-activating missense mutations in non-small cell lung cancer: a retrospective ATLAS cohort study
Authors: Yang Guangjian , Liu Runze , Li Pei , Yang Yaning , Wang Yajie , Mao Huiqing , Tang Xiaoyong
Published: July 2024

Background

Unlike human epidermal growth factor receptor 2 (HER2) amplification or exon 20 insertions, missense mutations in the extracellular domain (ECD), transmembrane domain (TMD), and intracellular domain (ICD) of the HER2 protein have been implicated as oncogenic in non-small cell lung cancer (NSCLC). However, their molecular subtypes, structural disparities, and clinical responses to current medical treatments, particularly HER2-targeted tyrosine kinase inhibitors (TKIs), remain unclear in NSCLC and warrant investigation.

Methods

A real-world observational ATLAS study was conducted to gather and analyze therapeutic outcomes of chemotherapy or TKIs for heterogeneous HER2 missense mutations in NSCLC. Computational models of typical ECD, TMD, and ICD mutations were utilized to explore their structural variances.

Results

We screened 37 eligible patients with HER2-activating missense mutations, of which 35 patients who had received chemotherapy or HER2-targeted TKIs as first-line therapy were available for response assessment. The median progression-free survival (PFS) for chemotherapy was 4.43 months (95% confidence interval [CI], 3.77–5.10), with an objective response rate (ORR) of 26.1% (6/23) and a disease control rate (DCR) of 17/23 (73.9%). The administration of afatinib, dacomitinib, and pyrotinib, HER2-targeted TKIs, achieved a median PFS of 4.65 months, with an ORR of 33.3% (4/12) and a DCR of 83.3% (10/12). Molecular modeling and computational simulations of ECD, TMD, and ICD mutations revealed their distinct structural characteristics.

Conclusion

In comparison to chemotherapy, HER2-targeted TKIs demonstrated similar activity and PFS benefits for HER2-activating missense mutations in NSCLC.
Feeding with plant powders increases longevity and body weight of Western honeybee workers (Apis mellifera)
Authors: Brown Andrew F. , Wiedmer Sarah , Retschnig Gina , Neumann Peter
Published: July 2024

Beekeepers routinely substitute honey from managed Western honeybee, Apis mellifera, colonies with sugar water post-harvest, potentially leading to malnutrition. Although nutritional supplements have been created, a general consensus on proper colony nutrition for beekeeping has yet to be reached. Thus, finding easily obtainable fortified A. mellifera food alternatives is still of interest. Here, we test plant powder–enriched food supplements since evidence suggests plant extracts can enhance dry body weight and longevity of workers. Freshly emerged workers were kept in hoarding cages (N = 69 days) and fed either with 50% (w/v) sucrose solution alone or additionally with one of 12 powders: Laurus nobilis, Quercus spp., Curcuma longa, Hypericum spp., Spirulina platensis, Calendula officinalis, Chlorella vulgaris, Melissa officinalis, Moringa oleifera, Rosa canina, Trigonella foenum-graecum, and Urtica dioica (N = 2028 workers total). The dry body weight was significantly increased in Quercus spp., Hypericum spp., Spirulina platensis, M. officinalis, M. oleifera, and T. foenum-graecum treatments. Further, the longevity was significantly increased in Quercus spp., C. longa, C. officinalis, C. vulgaris, M. officinalis, R. canina, T. foenum-graecum, and U. dioica treatments. Given that plant extracts can enhance A. mellifera health (i.e., phenolics, flavonoids), plant powders possibly provide additional macro- (i.e., proteins, lipids, peptides) and micronutrients (minerals and vitamins) thereby enhancing nutrient availability. Further investigations into the mechanisms underlying these effects and field studies are recommended to validate these findings in real-hive scenarios.
Influence of nutrition on honeybee queen egg-laying
Authors: Fèvre Damien P. , Dearden Peter K.
Published: July 2024

The honeybee queen is the engine of the colony, laying thousands of eggs that develop into larvae, nurse bees, and foragers. In turn, pollen and nectar from the environment, matured into bee bread and honey in the hive, transformed by digestion to royal jelly by the worker community, fuel queen egg-laying. The queen relies on this food supply chain to produce large numbers of eggs during the high season when pollen and nectar are in abundance. Despite the importance of egg-laying for the productivity of a colony, few studies have evaluated the influence of nutrition on the quantity and quality of eggs. This review aims to describe food processing from the queen’s mouth to egg provisioning, by exploring the nutritional cues that trigger queen egg-laying, the subsequent pathways involved, and the factors that influence them.
A Newly Dated Late Pleistocene and Holocene Archaeological Assemblage from Bukhtarma Cave in the Southern Altai Piedmont, East Kazakhstan
Authors: Iovita Radu , Rendu William , Lindauer Susanne , Taimagambetov Zhaken , Kushch Galina A. , Baryshnikov Gennady F.
Published: July 2024

The Altai mountains contain a number of cave and rockshelter sites that have given crucial information about human evolution in Asia. Most of these caves are located in the Gornyi Altai of Siberia, while the southern flank of the range remains much less known. Bukhtarma Cave was a karstic cave located near the former village of Peshchera, on the banks of the Bukhtarma River running through the foothills of the southern (Kazakh) Altai mountains. The Soviet East Kazakhstan Archaeological Expedition carried several excavation campaigns in the cave in the early to mid 1950s, discovering Paleolithic stone tools as well as animal bones. The collections were split between the East Kazakhstan Regional Museum of Local History in Öskemen (the lithic and part of the faunal collection) and the Zoological Institute in Leningrad (now St. Petersburg) (most of the fauna). Subsequently, the site was flooded by the construction of the Bukhtarma Reservoir in 1958, such that further fieldwork is impossible. However, in 2020, we reanalyzed the zooarchaeological collections and obtained several 14C dates. Based on the excavation documentation and the newly obtained dates exclusively taken from cut marked and carnivore-modified bone, we reconstruct at least three Paleolithic archaeological horizons, spanning the time between ca. 47–30 ka cal BP and exhibiting Middle and Upper Paleolithic characteristics, as well as the remains of several Holocene occupations, the latest of which dates to the Bronze Age. We present here a summary of the lithic and faunal assemblage and draw general conclusions about the site’s placement within the regional Paleolithic.
Assessment of blended cement containing waste basalt powder: physicomechanical and electrochemical impedance spectroscopy investigations
Authors: Abo Hashem Israa A. , Gaber Ghalia A. , Ahmed Amal S. I. , Abdel Ghany Nabil A.
Published: July 2024

Basalt powder (BP) is the residue of a plant that crushes basalt stones. This work deals with the effect of waste BP on the properties of cement mortars and the physical properties of hardened mortars. Modified concrete was prepared by partial replacement of BP in amount of 5, 10, 20% by weight of cement. Physico-mechanical properties and corrosion resistance were investigated. Electrochemical impedance spectroscopy (EIS) was used to examine the corrosion behavior of cement pastes with a partial addition of basalt powder in aggressive solutions of 5% NaCl and 5% MgCl2 for up to 270 days. Infrared spectroscopy (IR), X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX) were also performed to investigate the hydration process and microstructure formation of the basalt blended paste. Results indicate that the addition of basalt powder as a partial replacement of cement influences the microstructure of the interfacial transition zone (ITZ), which is denser and stronger than in cement paste without basalt powder. The filler effect of the basalt powder improves the compressive strength of cement paste. Also, comparing BP0 and BP20 in 5% NaCl after 270 days, the partial substitution of cement with BP resulted in a higher compressive strength of 671 and 895 kg/cm2, respectively. The EIS results also showed the highest values of Rp 953 ohms cm2 after 270 days. This high corrosion resistance might indicate the binding by high Al2O3 that reduced the free aggressive chloride ions in the solution.
Toward a social-ecological forest landscape restoration assessment framework: a review
Authors: Löhr Katharina , Eshetu Shibire Bekele , Moluh Njoya Hamza , Hagan Jonathan Antwi , Gebremedhin Asmelash Tesfaye , Hounkpati Kossi , Raharinaivo Hamy , Rakoto Ratsimba Harifidy , Bekele Tsegaye , Adjonou Kossi , Kokou Kouami , Sieber Stefan
Published: July 2024

The urgency to restore landscapes to counteract deforestation, soil degradation, and biodiversity loss has resulted in a global commitment to landscape restoration. Many frameworks and tools have emerged for the design and implementation of restoration activities. The frameworks tend to focus on selected dimensions of sustainability, with the majority focusing on the ecological. Current frameworks miss a balanced assessment of (planned) interventions taking into account also the social dimension relating to participation and ownership as well as improvement of livelihoods. The objective of this review is to assess current frameworks for identification of strength and weaknesses and to derive an integrated Forest Landscape Restoration (FLR) assessment framework model that shall help overcome current limitations. Applying systematic literature review, a total of 22 frameworks are selected and analyzed in-depth applying qualitative content analysis. Our review finds that frameworks vary with respect to their focus and restoration objectives. They also differ in relation to spatial and temporal scale, degree of stakeholder participation, consideration of ecological and social dimensions, monitoring and evaluation approaches, as well as provisions for exit strategies. Findings are summarized in form of an integrated FLR assessment framework, comprising six interlinked components: stakeholder participation, customization, time and scale of application, social-ecological balance, monitoring, evaluation and learning, and exit strategy. The proposed framework facilitates design and implementation of context specific interventions, balancing the nexus of social and ecological dimensions of FLR and acknowledges the need to also include reflection on learnings and planning of an exit strategy for long-term success.

Graphical Abstract
Sustainable AI and the third wave of AI ethics: a structural turn
Authors: Bolte Larissa , van Wynsberghe Aimee
Published: July 2024

With the introduction of the concept of Sustainable AI, considerations of the environmental impact of the technology have begun to enter AI ethics discussions. This, Aimee van Wynsberghe suggests, constitutes a new “third wave of AI ethics” which yet needs to be ushered in. In this paper, we ask what is entailed by Sustainable AI that should warrant such special accentuation. Do we find simply run-of-the-mill AI ethics applied to an environmental context? Or does Sustainable AI constitute a true a “game-changer”? We engage in a discussion about what the “waves of AI ethics” ought to mean and the criteria for labelling a wave as such. We argue that the third wave of AI ethics rests on a turn towards a structural approach for uncovering ethical issues on a broader scale, often paired with an analysis of power structures that prevent the uncovering of these issues.
Examining the non-linear impact of fossil and renewable energy consumption on Vietnam’s ecological footprint: insights from the asymmetric ARDL approach
Authors: Nam Le Phuong , Hang Nguyen Thi Bich , Van Song Nguyen , Eluriagac Louie Marie T.
Published: July 2024

Vietnam’s economy is rapidly growing, marked by an increasing reliance on fossil fuels and renewable energy sources, resulting in unsustainable consumption patterns. The primary objective is to investigate the implications of renewable and non-renewable resource consumption on the overall resource availability over the long term, as indicated by the ecological footprint. Furthermore, the study incorporates economic growth to examine the Environmental Kuznets Curve hypothesis in Vietnam. Methodologically, the study adopts the asymmetric Autoregressive Distributed Lag model, utilizing time-series data ranging from 1986 to 2022. The findings highlight that Vietnam’s economic growth still use more natural resources while compromising the overall ecological reserve. Furthermore, the research findings suggest that the Environmental Kuznets Curve hypothesis does not hold in the context of Vietnam. Specifically, the increasing share of primary energy sourced from fossil fuels is observed to coincide with an increase in demand in ecological footprint. In contrast, an increase in primary energy consumption from renewable sources demonstrates a marked reduction in natural resource demand over the long term. Several strategies are recommended to enhance the resilience of environmental resources, such as adopting new and energy-efficient technologies is necessary within the industrial sector, promote the utilization of renewable energy sources, enhance waste management systems, transition from conventional energy to renewable sources in both production and consumption and the formulation of legislation on renewable energy usage.
Pressureless sintering kinetics analysis of Ti3SiC2 and Ti2AlC powdered MAX phases
Authors: Córdoba Gallego José M.
Published: July 2024

This paper reports the pressureless sintering behavior and the activation energy of the powdered MAX phases Ti3SiC2and Ti2AlC. A non-isothermal technique was used to determine the sintering kinetic parameter. The Ti3SiC2and Ti2AlC MAX phases showed the maximum sintering rate at 1723 K, 0.14 and 0.10 µm/s, respectively. The sintering rate of the sample at different temperatures followed a cubic equation which was determined. The sintering activation energy (Ea) for the Ti3SiC2and Ti2AlC samples was 362.1 kJ/mol and 640.3 kJ/mol, respectively.
Scaffold-free development of multicellular tumor spheroids with spatial characterization of structure and metabolic radial profiles
Authors: Bess Shelby N. , Smart Gaven K. , Igoe Matthew J. , Muldoon Timothy J.
Published: July 2024

Purpose

In vitro assays are essential for studying cellular biology, but traditional monolayer cultures fail to replicate the complex three-dimensional (3D) interactions of cells in living organisms. 3D culture systems offer a more accurate reflection of the cellular microenvironment. However, 3D cultures require robust and unique methods of characterization.

Methods

The goal of this study was to create a 3D spheroid model using cancer cells and macrophages, and to demonstrate a custom image analysis program to assess structural and metabolic changes across spheroid microregions.

Results

Structural characterization shows that cells at the necrotic core show high normalized fluorescence intensities of CD206 (M2 macrophages), cellular apoptosis (cleaved caspase-3, CC3), and hypoxia (HIF-1α and HIF-2α) compared to the proliferative edge, which shows high normalized fluorescence intensities of CD80 (M1 macrophages) and cellular proliferation (Ki67). Metabolic characterization was performed using multiphoton microscopy and fluorescence lifetime imaging (FLIM). Results show that the mean NADH lifetime at the necrotic core (1.011 ± 0.086 ns) was lower than that at the proliferative edge (1.105 ± 0.077 ns). The opposite trend is shown in the A1/A2 ratio (necrotic core: 4.864 ± 0.753; proliferative edge: 4.250 ± 0.432).

Conclusion

Overall, the results of this study show that 3D multicellular spheroid models can provide a reliable solution for studying tumor biology, allowing for the evaluation of discrete changes across all spheroid microregions.
Impact of cluster farming on wheat productivity and net benefit among smallholder farmers in Lemu-Bilbilo and Hetosa districts of Arsi Zone, Ethiopia
Authors: Degefu Sura , Sileshi Million , Ogeto Mohammed Aman
Published: July 2024

This study focuses on identifying the determinants of cluster farming participation decisions and the impact of cluster farming on smallholder wheat farmer’s productivity in the two districts of Arsi Zone, Ethiopia. The study utilized cross-sectional data and a multistage sampling procedure to select a total of 381 respondents from the two districts of Arsi Zone, Ethiopia. The endogenous switching regression model was employed to achieve the research objectives. The study result indicates that sex of the household head, education level, size of cultivated land, access to training, membership in a farmer's cooperative, access to information and social responsibility of the household head influenced cluster farming participation positively and significantly, while distance from the nearest market had a negative and significant effect on cluster farming participation. Furthermore, the study shows that, if participants had decided not to practice cluster farming, their wheat yield and net benefit would have decreased by 33.57 and 40.08%, respectively. Similarly, had non-participants decided to participate, their wheat yield and net benefit would have increased by 46.79 and 102.49%, respectively. The study recommends that policymakers and development organizations should consider cluster farming as a main strategy to increase smallholder farmer’s productivity. Moreover, the study calls for government and institutional assistance in the areas of education services, training, extension services, infrastructure (particularly access to markets), and cooperative development. Moreover, policy and development measures should address the issue of gender disparities in cluster farming participation.
The Association of Arterial Pulse Wave Velocity with Internal Carotid Artery Blood Flow in Healthy Subjects: A Pilot Study
Authors: Sultan Salahaden R.
Published: July 2024

Background

Arteriosclerosis significantly impacts cardiovascular health. Pulse wave velocity has emerged as a valuable non-invasive method for assessing arterial stiffness. A negative association between carotid-femoral pulse wave velocity (cfPWV) and cerebral blood flow has been reported, suggesting a link between arterial stiffness and reduced cerebral blood flow. We aimed to determine whether a correlation exists between cfPWV and blood flow in the internal carotid artery (ICA) and to assess the influence of age and body mass index (BMI) on cfPWV in healthy individuals.

Methods

Thirty-six healthy subjects (23 males and 13 females) with no underlying medical conditions and who were not on regular medications were enrolled in the study. Arterial stiffness was assessed by measuring the cfPWV using Vicorder® software. ICA blood flow parameters were measured using high-resolution ultrasound. ICA diameter was measured using automated edge-detection software.

Results

Significant positive correlations were found between cfPWV and age (Spearman’s rho coefficient 0.33, p = 0.04), BMI (Spearman’s rho coefficient 0.32, p = 0.05), and ICA diameter (Pearson’s coefficient 0.35, p = 0.03). No significant correlations were observed between cfPWV and ICA peak systolic velocities (PSV; p = 0.22), or resistive index (RI; p = 0.76), nor between age and ICA diameter (p = 0.42), PSV (p = 0.09), or RI (p = 0.89).

Conclusion

Our findings demonstrate a positive correlation between arterial stiffness, age, and BMI in a healthy population, along with an association between increased ICA diameter and arterial stiffness. The lack of correlation between cfPWV and ICA blood flow parameters suggests that the ICA may dilate as a compensatory mechanism to mitigate the effects of increased arterial stiffness, ensuring optimal cerebral blood flow in healthy individuals.
Preliminary development of the Survey on Flourishing: measuring subjective well-being in an adolescent sample
Authors: Salazar Gus C. , Warren Jared S.
Published: July 2024

Background

Adolescent subjective well-being is a topic that has gained significant focus over recent years. This focus is reflected in forming measurement tools and interventions to better understand better and improve adolescent mental health. While these steps are necessary, problems still exist regarding adolescent subjective well-being measurement. Notably, current measurement tools are limited in their content, applicability to various populations, and accessibility.

Aims

This paper examines the psychometric properties of the Survey on Flourishing (SURF) when used with an adolescent sample from the United States.

Method

A sample of 334 participants participated in the present study. We examined the reliability and validity of the SURF by examining its internal consistency, convergent validity, and discriminant validity. We also examined the factor structure of the SURF using a confirmatory factor analysis (CFA).

Results

The SURF demonstrated high internal consistency (α = 0.92), a strong positive correlation with convergent measures, and a weak negative correlation with a discriminant measure. A one-factor model best fits the observed data.

Conclusion

The SURF demonstrated good psychometric properties and addressed several shortcomings in current measures. Preliminary data suggests the SURF may be a useful and practical measure of adolescent subjective well-being.
Convergent antitrust regulation of the digital economy in China, the European Union and the United States: mirror of an intensifying geopolitical competition
Authors: Ma Aifang
Published: July 2024

China, the European Union, and the United States are the three largest digital economies in the world. This article compares the antitrust regulation of the digital economy in the three regions after the 2000s. It argues that over time, the antitrust regulation of the digital economy in the three regions tends to converge along three dimensions: growing separation of the antitrust regulation of the digital economy from that of the other economic sectors, convergence of regulatory objectives, and convergence of regulatory methods. In combination with the geopoliticization of the platform economy, this article argues that four factors have contributed to shape such convergence: (1) historical factors, (2) globalization of the digital economy, (3) increasing policy imitation and policy competition among the major digital powers of the world, (4) support from the civil society.
Comparison of the mechanical characteristics of biocomposites of unsaturated polyester resin with cellulose extracted from corn silk and treated corn silk
Authors: Ali Md. Farhad , Shabur Md. Abdus , Safiur Rahman G. M.
Published: July 2024

The purpose of this study is to extract cellulose from corn silk (CS) fiber and use it as a reinforcing filler in unsaturated polyester resin (UPR) matrix. In this study, the cellulose is characterized using a Fourier Transform Infrared Spectrometer (FTIR), and the resulting UPR/cellulose biocomposite's mechanical properties (such as flexural and impact testing) are assessed. Scanning electron microscopy (SEM) provided strong support for mechanical rather than a chemical bond between fiber and UPR. Additionally, the sodium hydroxide treated CS in UPR biocomposite and comparing it with neat UPR. The agricultural byproduct rich in cellulose corn silk is a natural polymer known for its structural strength and UPR has garnered attention as a biopolymer with notable flexibility, making it an appealing choice for plastic product manufacturing. However, the drawback of UPR lies in its inherent deficiency in both stiffness and strength. According to the FTIR data, extracted cellulose (CS) had fewer ketone (C = O) and hydroxyl (-OH) groups than virgin cellulose. It was shown that throughout the extraction process, hemicellulose and lignin were more eliminated, producing a more pure form of cellulose. When filled in UPR, cellulose and treated CS both caused the impact strength of UPR biocomposites to drop. For both treated CS and cellulose, it was shown that the flexural modulus and flexural strength increased as the filler amount increased to a definite percentage (12%) after which it decreased. The result revealed the tensile strength and tensile modulus achieved by 0% of fiber with 48 N/mm2 and 51 N/mm2 and highest at 12% of fiber with 54.3 N/mm2 and 68.8 N/mm2 for CS + UPR. And 53.4 N/mm2 and 69.6 N/mm2 for cellulose + UPR composite,, respectively. In comparison, the flexural characteristics of UPR/cellulose were marginally inferior to those of UPR/treated CS. However, the impact resistance showed a significant improvement, particularly with a cellulose loading of 12%. Hence, cellulose presents a greater potential for composite manufacturing due to its ability to maintain the ductile properties of UPR compared to treated CS. Moreover, processed CS and cellulose both can be used as reinforcing agents in polymers to increase their strength and stiffness.
From organic farming to agroecology farming, what challenges do organic farmers face in Central Uganda?
Authors: Dagoudo Bienvenu Akowedaho , Ssekyewa Charles , Ssekandi Joseph , Ngom Khady , Naigaga Hellen , Moumouni Ismail M. , Noba Kandioura
Published: July 2024

Revealed as a production system that does not use synthetic fertilizers or pesticides, organic farming is recognized as ecological production and has been institutionalized in Uganda. Organic production continues to face the challenges of what is considered agroecology farming, which is viewed nowadays as an opportunity for creating new value chains and food systems for agricultural production based on protecting the environment and supplying nutritious and safe foods to society. This paper focuses on agroecology farming indicators to assess organic farming in order to highlight the challenges organic farmers face in implementing agroecology practices. The data collection was carried out in 5 districts in Central Uganda: Wakiso, Masaka, Bukomansimbi, Ssembabule, and Kyotera. A multiple-stage stratified sampling was used to select 310 organic farmers in 5 districts. Various representations and correlation analyses of agroecology indicators have been conducted using descriptive statistics and correlation tests. The findings show that 51.9% of organic farmer respondents have at least three crops produced in the local climate for a long time, and 58.71% of organic farming has medium integration (animal feed is mostly self-produced and grazed, and their manure is used for compost and fertilizer). It highlights that seeds and animal genetics are self-produced, neighbor farms exchange them, and some specifics are purchased at local markets for 51.61% organic farming. The results revealed that 61.61% of organic farms visited had half of the arable soil covered with organic residues. The correlation test revealed that there is a significant positive correlation between diversity animal genetics and crop and livestock integration (r = 0.674, p < 0.01), between harvesting and saving water systems and resilience and adaptability to climate variability (r = 0.546, p < 0.01), and between diversity crops and diversity activities and services (r = 0.523, p < 0.01). Despite the interdependence of organic farming's agroecology practices, most residues and waste are not recycled or reused as organic fertilizer, and organic farmers have limited equipment to harvest and save water for production. This is an opportunity for organic stakeholders to invest in organic residues and waste recycled equipment in order to create a new value chain for organic production by producing organic fertilizers and biopesticides.
Do Perceived Benefits Compensate for Low Provider Trustworthiness in Disclosure Decisions?
Authors: Gieselmann Miriam , Hagedorn Josephine , Sassenberg Kai
Published: July 2024

Abstract: People regularly receive algorithm-based recommendations (e.g., in social media and online shopping). Today, such algorithmic recommendations cover a wider range of applications, such as finding recipes that match an individual’s needs and food preferences. To give better-fitting recommendations, algorithms incorporate large amounts of personal information about the individual, which raises the issue of privacy concerns. When are people willing to share such information that can then be considered by algorithms? While previous research has indicated that perceived benefits of platform use and provider trustworthiness influence whether people are willing to disclose personal information, these studies often have two major limitations: they are either survey-based – thus, not allowing causal conclusions – or lack realistic usage (i.e., rely on vignettes). Thus, in the present experimental study ( N = 329), we manipulated provider trustworthiness and asked participants about their willingness to disclose information directly after interacting with an algorithm-based system for recipe recommendations. Results indicate that higher perceived benefits and provider trustworthiness are related to more willingness to disclose information. However, these effects are independent of each other. Thus, the present research suggests that provider trustworthiness causally leads to a higher willingness to share information and high benefits do not compensate for low provider trustworthiness.
Quantifying Downward Radiative Fluxes From Nighttime Martian Water Ice Clouds: Applications to Thermal Modeling of Surface Temperatures
Authors: Gary‐Bicas C. E. , Rogers A. D. , Piqueux S.
Published: July 2024

During the first part of the Martian year (Ls = 50°–160°) a phenomenon occurs on Mars in the tropical and equatorial regions (30°N–10°S) known as the Aphelion Cloud Belt (ACB). During this time, there is prominent formation and diurnal variability of water ice clouds. Limited empirical attempts have been made to characterize the magnitude of radiative flux contributions from clouds to nighttime surface temperatures. In this work, we estimated the infrared (IR) flux contribution at ground level from the clouds by comparing surface temperature data from the Thermal Emission Spectrometer (TES) onboard Mars Global Surveyor (MGS) to calculated temperatures using the KRC numerical thermal model. We then generated a database of IR fluxes at the ground contributed by clouds spanning the entirety of the tropical and equatorial regions as a function of Solar Longitude (Ls) on Mars in one degree bins. We compared results with work presented elsewhere in the literature and found good agreement. We also found that temporal trends followed the general established range for the ACB but our analysis demonstrated the peak ACB values occurred at later times (Ls = 100°–140°) than previously published data sets using water ice opacity retrievals (Ls = 90°–110°). This database may be used in comparison to calculated Global Climate Model fluxes as well as a lookup tool for more precise estimation of surface and subsurface thermal environments in these regions.
Dust Emissions on Mars From Phoenix Lidar Measurements in Relation to Local Meteorological Conditions
Authors: Kahnert M. , Ceolato R.
Published: July 2024

The diurnal cycle of dust aerosols on Mars is studied by analyzing lidar observations at the Phoenix landing site under cloud‐ and fog‐free conditions and in the absence of elevated, long‐range transported dust layers. There is a pronounced diurnal cycle in the dust‐layer height with minimum heights of 4–6 km occurring between 11:00 and 17:00 local time. The ratio of the aerosol optical depth (AOD) within the lowermost 2 km to the total AOD reaches peak values at the same time. This can be explained by local dust emissions driven by the diurnal cycle of heating and cooling in the boundary layer. Analysis of wind and pressure measurements show that the gustiness of surface winds and the frequency of convective vortices undergo diurnal variations resembling those of AOD, indicating that these processes are the main drivers for local dust emissions.