bluuebunny/crossref_metadata_2025 huggingface dataset:
Number of Stairs at Home is Associated with Discharge to Post-Acute Care Facility Following Total Knee Arthroplasty
Authors: Williams Jaques , Held Michael B. , El Othmani Mouhanad , Neuwirth Alexander L. , Geller Jeffrey A. , Cooper H John , Shah Roshan P.
Published: August 2023

Background

Discharge to post-acute care facility (PACF) carries significant cost and quality burdens to patients undergoing total knee arthroplasty (TKA). In a recent study of pre-bundled payment model patients, the number of stairs (NOS) at home did not influence discharge to PACF for total hip arthroplasty. However, no study has yet examined NOS as it relates to discharge destination after TKA. In a large metropolitan market, it is not uncommon to have several flights of stairs leading to a home. We hypothesize that the number of unavoidable stairs to enter a home is a significant risk factor for discharge to PACF.

Methods

We reviewed 557 patients who underwent elective TKA at a single urban academic medical center between November 2011 and October 2014. Demographic data as well as NOS, ASA score, RAPT score, LOS, operative time, and tranexamic acid use were collected. T-tests, ANOVA, and Kruskal-Wallis analysis were conducted followed by a logistic regression to compare associations of factors to discharge to PACF.

Results

Of the 540 patients included in analysis, 193 (35.7%) were discharged home and 347 (64.3%) were discharged to a PACF. NOS (OR=1.457, p<0.001) and increased age (OR=1.057, p<0.001) were found to be significant risk factors for discharge to PACF while female sex (OR=0.57, p=0.013) and higher RAPT scores (OR=0.83, p=0.004) were protective against discharge to PACF.

Conclusion

With the conclusion of recent bundled payment programs, financial carrots may disappear, though it is likely that sticks will remain. Therefore, all risk factors must be identified and addressed. We found, in a pre-bundled payments era, that stairs is a risk factor for non-home discharge in a metropolitan population, and we confirmed other known risk factors of older age, higher ASA score, and lower RAPT score.
Risk Factors for Unexpected Hospital Admission Following Achilles Tendon Repair: A National Database Study
Authors: Tarazi John M. , Partan Matthew J. , Aminov Areil , Sherman Alain E. , Bitterman Adam D. , Cohn Randy M.
Published: August 2023

INTRODUCTION

Achilles tendon rupture (ATR) repair is one of the most common orthopaedic surgeries performed in the United States, however there is a paucity of literature on predisposing risk factors for hospital readmissions. The purpose of this study is to identify risk factors for 30-day readmission in patients undergoing ATR repair with emphasis on procedures performed in the outpatient setting. Specifically, we examine: 1) 30-day post-operative hospital readmission rates; 2) the medical comorbidities and patient characteristics that predisposed this cohort to post-operative complications; and 3) the complications leading to readmission. 

METHODS

The ACS-NSQIP was queried for patients who underwent ATR from 2015 to 2019 using CPT code 27650 in all fields yielding a sample size of 3,887 cases. The following demographic, lifestyle, and comorbidity variables were recorded: age, sex, race, BMI, morbid obesity (BMI ≥ 40.00 kg/m2), bleeding disorders, chronic obstructive pulmonary disease (COPD), diabetes mellitus, hypertension, tobacco use, and chronic steroid use. The primary outcome of 30-day readmission was defined as unplanned hospital readmission likely related to the principal procedure. Independent samples Student’s t-tests, chi-squared, and, where appropriate, Fisher’s exact tests were used in univariate analyses to identify demographic, lifestyle, and peri-operative variables related to 30-day readmission following ATR. Multivariate logistic regression modeling was subsequently performed. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated and reported.

RESULTS

Of the 3,887 patients included in our sample, 28 were readmitted within the 30-day post-operative period, corresponding to a readmission rate of 0.73%. Significant relationships with univariate analyses between readmission status and the following patient variables included: mean patient age (p = 0.02); hypertension (p < 0.001); BMI (p = 0.01); morbid obesity (p = 0.002); ASA Classification (p = 0.006); and bleeding disorders (p = 0.03). Multivariate logistic regression modeling confirmed that the following patient variables were associated with statistically significantly increased odds of readmission: age, p = 0.02), OR = 1.03, 95% CI [1.01, 1.06]; hypertension, p < 0.001, OR = 3.82, 95% CI [1.81, 8.06]; BMI, p = 0.01, OR = 1.06, 95% CI [1.01, 1.11]; morbid obesity, p = 0.004, OR = 3.53, 95% CI [1.49, 8.36].

CONCLUSION

Our study indicated that only 0.73% of patients were readmitted after their outpatient procedure. Patients who: 1) have BMIs greater than 40; 2) are older in age 3) have hypertension; and 4) a higher ASA Classification were at increased risk for readmission.
ANÁLISE DA RELEVÂNCIA DO CONSENTIMENTO PARA CONFIGURAÇÃO DO TRÁFICO INTERNACIONAL DE PESSOAS
Authors: Da Silva Favalessa Liliane , Vilela Ramos Fonseca Luma , Jacob Alexandre
Published: August 2023

O presente estudo aborda o tráfico internacional de pessoas, com foco no público feminino, um crime grave que envolve a exploração e o transporte de indivíduos através das fronteiras. A análise da relevância do consentimento na configuração desse ilícito é importante para entender sua natureza complexa. Embora muitas vítimas sejam atraídas por promessas enganosas, é crucial compreender que a falta de consentimento não é o único elemento determinante para configuração desse crime. Ao longo da história, o tráfico de pessoas tem sido uma prática frequente na sociedade global, remontando ao período colonial em que milhares de africanos foram violentamente separados de suas famílias, transportados em navios negreiros e vendidos como escravos. Infelizmente, mesmo nos tempos atuais, a escravidão persiste em formas diversas. Mulheres são especialmente vulneráveis à escravidão sexual em várias partes do mundo, enfrentando uma falta de proteção efetiva. Apesar dos esforços das organizações internacionais para combater o tráfico de pessoas para fins sexuais, os resultados alcançados até o momento têm sido insatisfatórios. Trata-se de um crime transnacional complexo, perpetrado de diferentes maneiras e envolvendo uma ampla rede de criminosos, o que torna seu enfrentamento extremamente desafiador.
A EFETIVIDADE DAS MEDIDAS SOCIOEDUCATIVAS DIANTE DOS MASSACRES EM ESCOLAS NO BRASIL
Authors: Da Silva Seixas Thainara , Jacob Alexandre
Published: August 2023

Os ataques em escolas brasileiras têm se tornado cada vez mais frequentes, gerando grande preocupação na sociedade e nas autoridades competentes. Este artigo tem como objetivo analisar as causas e consequências desses ataques, bem como as medidas que foram tomadas para prevenir sua ocorrência. Para tanto, foi realizada uma pesquisa bibliográfica sobre o tema, abrangendo estudos e pesquisas realizados por especialistas em segurança, psicologia e educação. Verificou-se que as causas dos ataques em escolas brasileiras são múltiplas e complexas, incluindo fatores sociais, psicológicos e culturais. Entre esses fatores, destacam-se o bullying, o isolamento social, a falta de diálogo e de apoio emocional, além do fácil acesso a armas de fogo. As consequências desses ataques são graves, envolvendo não apenas o trauma para as vítimas e suas famílias, mas também o impacto na segurança e na qualidade da educação no país. Por fim, foram apontadas algumas medidas que ocorrem após o cometimento de atos infracionais, assim como debates com o objetivo de conter esses ataques.
REITEGRAÇÃO SOCIAL DO CONDENADO:
Authors: Alvarenga Pereira Gama Andressa , Jacob Alexandre
Published: August 2023

A pesquisa trata de reintegração social e estigmatização do condenado. Analisa as dificuldades de ressocialização no sistema prisional a partir da oferta das assistências legais. Por meio de levantamento bibliográfico e percepção de egressos do sistema prisional, conceitua os institutos relacionados e contextualiza o sistema prisional. Demonstra que as assistências legais estão diretamente relacionadas aos bons resultados na reintegração social. Avalia, por meio da percepção dos egressos, que a situação fática difere em muito da legal. Conclui que há problemas no cárcere a serem resolvidos quanto às assistências legais e que devem ser resolvidos para que a reintegração social seja efetiva.
Implementasi Kriptografi Pengamanan Data File Dokumen Menggunakan Algoritma Advanced Encryption Standard Mode Chiper Block Chaining
Authors: Manullang Sahat
Published: August 2023

Dalam meningkatkan aspek keamanan suatu data dapat dilakukan dengan pengendalian teknik kriptografi. Algoritma AES (Advanced Encryption Standard) merupakan kriptografi yang dapat digunakan untuk melindungi data atau informasi dengan melakukan mengenkripsi dan mendekripsi blok data sepanjang 128 bit dengan panjang kunci 128 bit, 192 bit, atau 256 bit. Proses pengamanan data dapat dilakukan dengan menggunakan metode Chiper Block Chaining (CBC) dalam mode operasinya. Dalam persiapan untuk melakukan proses enkripsi yang digunakan adalah sebuah file dokumen pdf. Data 16 byte pertama dibaca sebagai blok pertama untuk proses enkripsi dengan metode CBC. Hasil dari penelitian yaitu dapat mengimplementasikan program aplikasi menggunakan algoritma Advanced Encryption Standard mode Chiper Block Chaining  dengan melakukan enkripsi dan dekripsi file dokumen.
IMPLEMENTASI PLATFORM AS A SERVICE (PAAS) PADA DATABASE E-COMMERCE BERBASIS CLOUD COMPUTING
Authors: Wadly Fachrid , Arpan  , Muttaqin Muhammad
Published: August 2023

Business competition in the field of information technology continues to increase, one of the technologies itself is cloud computing. Cloud computing can be public or private. One type of cloud computing service used in this study is PaaS. The PaaS cloud computing service provides a platform that users can use to create applications. The Byna Cake shop is a shop that opens a cake business in Aceh, which is located on Pulau Tiga, Aceh, Tamiang. This shop sells various types of cakes which have been produced manually by themselves since 2021. The sales system uses WhatsApp and Instagram media and comes directly to the store, so this system is considered to be less effective and efficient. Therefore, an online sales system is needed, namely by building a web-based E-Commerce application. In implementing this web-based e-commerce application, the author utilizes cloud infrastructure as a cloud provider, namely Microsoft Azure. Computing service used in this research is CMS AbanteCart. Web-based e-commerce application at the Byna Cake store created by configuring a virtual machine to install CMS AbanteCart Packaged By Bitnami on the Microsoft Azure platform. The design used in creating web-based e-commerce applications at the Byna Cake store uses Use Cases and Class Diagrams.
ANALISIS FITUR APLIKASI CINCAU STATION DENGAN METODE CUSTOMER KNOWLEDGE MANAGEMET (CKM)
Authors: Arya Reinanta Putra Theofilus Dewa , Maximillian Louis , Reinaldo Dionisius , Prutanda Ryan
Published: August 2023

In the era of globalization, business competition is fierce, especially in the food and beverage industry. Cincau Station, which initially only served ice cincau with palm sugar, has developed into a variety of flavors and can be accessed through a mobile application. However, this application has shortcomings in design and features that can affect consumer interest. This research uses the Customer Knowledge Management (CKM) method to analyze the UI/UX of the Cincau Station application. CKM is an approach that considers customer needs to develop ideal products. The goal of CKM is to achieve brand effectiveness and competitiveness. This research limits the analysis to the content and composition aspects of the application.

 

Keywords: Cincau Station, Customer Knowledge Management (CKM), Design, Effectiveness, Mobile Application, UI/UX
Rancang Bangun Web Profil Program Studi Perpajakan Berbasis Wordpress (Studi Kasus: Universitas Pembangunan Panca Budi Medan)
Authors: Erika Winda
Published: August 2023

Website menjadi salah satu sistem informasi yang mudah diakses oleh masyarakat secara online. Prodi Perpajakan Universitas Pembangunan Panca Budi membutuhkan website sebagai media untuk promosi yang berisi informasi tentang visi dan misi, data dosen Perpajakan, tentang Prodi Perpajakan, prestasi mahasiswa, pengetahuan Prodi Perpajakan, serta prospek kerja lulusan Prodi Perpajakan. Teknik pengumpulan data dilakukan secara observasi dan wawancara kepada Kaprodi Perpajakan Universitas Pembangunan Pnca Budi dan disesuaikan dengan kebutuhan prodi dalam pembuatan web Profil. Proses perancangan website profil Prodi Perpajakan meggunakan wordpress. Dimana wordpress merupakan sebuah aplikasi terbuka yang digunakan sebagai mesin blog yang dibangun dengan bahasa pemrograman PHP dan Pangkalan data MySQL
Presence of Bilateral Rectus Sternalis Muscles in an 88-Year-Old White Female Donor
Authors:   Edward Hebert School of Medicine, Uniformed Services University of Health Sciences, Bethesda, USA, Carr Kyle , Clemens Bradford , Reeves Craig ,   Edward Hebert School of Medicine, Uniformed Services University of Health Sciences, Bethesda, USA, Fleisher Sarah , Silva Ilana , Cross Danielle , Arave Mariah , Granite Guinevere ,   Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, USA, Wind Gary ,   Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, USA, Ximena Leighton Maria ,   Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, USA, Maynes Elizabeth ,   Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, USA
Published: August 2023

The rectus sternalis muscle is a rare anatomical variant present in the anterior chest wall of humans. This study presents a case of rectus sternalis muscles found in an 88-year-old White female donor during an anatomy course. The embryology and function of this vestigial muscle remain unclear. The muscle has clinical significance in breast augmentation surgery and mammography. In surgery, the muscle can be used to improve the end quality of breast augmentations. In mammography, the rectus sternalis muscle can mimic irregular masses in the breast, leading to misdiagnosis. Advanced imaging techniques such as magnetic resonance imaging and computed tomography scans can confirm the presence of rectus sternalis muscle. Lack of awareness of this muscle can result in surgical complications and unnecessary procedures. Physicians should be aware of this anatomical variation to ensure accurate diagnosis and appropriate surgical planning.
Digital humaniora og teknologi forståelse
Authors: Berthelsen Ulf Dalvad
Published: August 2023

Der er i de senere år blevet brugt mange ressourcer på at integrere nye digitale teknologier på alle niveauer af uddannelsessystemet, både på policyniveau og i praksis. I grundskolen taler man om teknologiforståelse, i gymnasiet om informatik og på universiteterne har man efterhånden forsøgt at sætte ’computational’ foran navnene på de fleste discipliner.

Det har imidlertid vist sig at være en meget stor udfordring at implementere teknologiforståelse og computationel tænkning i skolernes, gymnasiernes og universiteternes veletablerede fag og fagforståelser (Tannert et al., 2021). Det har generelt været en udfordring inden for mange fagområder, men særligt inden for de humanistiske fag synes der at være en diskrepans mellem fagenes identiteter og etablerede fagforståelser og den nye datalogiske faglighed. Dette har resulteret i, at mange humanistiske fag har valgt at løse opgaven ved at implementere et kritisk og sociologisk orienteret perspektiv med fokus på, hvordan teknologi påvirker hverdagsliv og kommunikation (Se fx Børne- og Undervisningsministeriet, u.å.-b, u.å.-a)  frem for et perspektiv, der udforsker hvordan datalogiske metoder og perspektiver kan udvide fagforståelsen.

Denne indstilling har rødder i en gammel tradition for teknologikritik inden for humaniora, der trækker på tankegods fra bl.a. Marx (1970), Horkheimer & Adorno (1969), Heidegger (1999) og forskellige poststrukturalistiske strømninger som fx actor network theory (Latour, 1999, 2005). Teknologikritikken har både været væsentlig og nødvendig, men har samtidig placeret humaniora i et modsætningsforhold til teknologi, herunder i særdeleshed digital teknologi og computationel tænkning.

I de senere år er der imidlertid, under den brede betegnelsen digital humaniora, opstået en strømning, der indtil videre først og fremmest er synlig på universiteterne, og som mere aktivt omfavner den digitale transformation. Med afsæt i et historisk rids over, hvordan den teknologikritiske position har udviklet op gennem det 20. århundrede, vil jeg i denne artikel diskutere, i hvilket omfang digital humaniora kan tilbyde en alternativ position, der gør det nemmere for de humanistiske fag dels at integrere teknologiforståelse i de eksisterende fagforståelser, dels at udvikle nye faglige identiteter som digitale humanister, for hvem avancerede digitale kompetencer og computationel tænkning indgår som en selvfølge i kompetenceprofilen.

Afslutningsvis diskuterer jeg, hvordan disse nye identiteter kan gøres tilgængelige for både elever og lærere i grundskolen og gymnasiet ved, i forlængelse af et emancipatorisk literacy-syn (Freire Paulo, 1985; The New London Group, 1996; Forfatter & Nielsen, 2021), at tage ejerskab over de nye digitale teknologier ved at tænke dem som et middel til kritik snarere end som målet for kritik.
Redaktionelt forord
Authors: Krarup Signe
Published: August 2023

I 2020 vedtog Danmark en klimalov med konkrete mål for reduktionen af drivhusgasser i 2030 og en hensigt om at være klimaneutralt senest i 2050 for at kunne leve op til Parisaftalens målsætning. Klimahensynet var det afgørende argument for den grønne omstilling af vores energiforsyning som nu er i gang. Med Ruslands invasion af Ukraine blev det imidlertid tydeligt, at denne omstilling haster, ikke kun pga. klimaet men også for at sikre en stabil og sikker energiforsyning. Pludselig stod Danmark og mange andre lande midt i en energikrise vi ikke havde set mangen til siden 70’erne. Og hvor en høj forsyningssikkerhed ikke længere var en selvfølgelighed.I dette temanummer om energi, sætter vi fokus på håndtering af energikrisen og hvordan Danmark kan opnå en grøn omstilling af vores energiforsyning, der samtidig sikrer forsyningssikkerhed, og et velfungerende el-marked med overkommelige priser for de europæiske forbrugere. Temanummeret illustrerer, at energipolitik i dag har mange dimensioner og at det internationale samarbejde er afgørende for at den grønne omstilling lykkes nationalt og globalt.
Da energipolitik blev sikkerhedspolitik
Authors: Berling Trine Villumsen
Published: August 2023

Danmark har i årevis været selvforsynende med olie og gas. Derfor var international storpolitik på gasområdet aldrig et spørgsmål om forsyning for Danmark. Vi var tilbagelænede, da Nord Stream-ledninger og Baltic Pipe var på tapetet og skulle forhandles. Men med Ruslands invasion af Ukraine blev energipolitik sikkerhedspolitik – også i Danmark. Denne artikel analyserer Danmarks bevægelse fra udenforstående til sanktions-fortaler i Østersøregionen og Europa.
Hvordan kan Europa få dækket sit behov for brint?
Authors: Münster Marie , Kountouris Ioannis , Bramstoft Rasmus
Published: August 2023

Det forventes, at brint bliver en vigtig brik i den grønne omstilling af det fremtidige energisystem. Brint kan især bidrage til omstilling af industrien samt til at producere brændstoffer til international transport. Denne artikel bygger på en analyse med energisystemmodellen, Balmorel. Der ses på minimering af omkostninger ved at opfylde Europas fremtidige brintbehov enten vedlokal produktion af brint via elektrolyse eller fra naturgas med CCS eller ved at importere brint fra andre steder. Resultaterne viser, at Danmark vil kunne dække den fremtidige nationale brintefterspørgsel samt have mulighed for at eksportere brint i forskellige fremtidige scenarier. Dog er det vigtigt, at vi betragter konkurrencen af brintproduktion baseret på solceller i Sydeuropa.
Basal cell adenoma of parotid gland: two case reports and literature review
Authors: Yoon Sungyeon , Kim Yesol , Moon Suk-Ho
Published: August 2023

Most of salivary tumors are benign in nature and are typically diagnosed and classified based on their histopathological presentation. Basal cell adenoma of the salivary glands is a rare, benign disease accounting for 1% to 3% of salivary gland tumors. Despite its low incidence, basal cell adenoma is the third most common benign tumor of the salivary gland after pleomorphic adenoma and Warthin’s tumor. It usually appears as a firm and slow-growing mass. Due to the prognosis, differential diagnosis with basal cell adenocarcinoma, adenoid cystic carcinoma and basaloid squamous cell carcinoma is required. In this report, we present two cases; a 62-year-old woman who presented with an asymptomatic, and slow-growing mass and a 64-year-old woman with a static-sized mass in the parotid gland. In both cases, the mass was completely excised, postoperative pathology reports confirmed the diagnosis of basal cell adenoma. We also review the literature and discuss this rare entity.
Diagnosis of split fractures of the mandible in adults
Authors: Kim Taesik , Jung Sung Gyun , Hong In Pyo , Hwang Young Joong
Published: August 2023

Background: Mandibular split fractures, in which the fracture occurs exclusively in the posterior wall, are uncommon. This study aimed to enhance clinicians’ understanding of mandibular split fractures and offer insights for future research.Methods: This study included six patients who visited our hospital between January 2020 and June 2023 and were diagnosed with mandibular split fractures. We retrospectively collected data from patients’ medical records on their age, sex, symptoms, mechanism, impact site, associated injuries, and treatment method, as well as the location, pattern, and number of fractures observed on computed tomography (CT) and panoramic images. The frequency of split fractures among all mandibular fractures was calculated.Results: The six patients included three men (50%) and three women (50%), ranging in age from 20 to 71 years (mean age, 49.8 years). The split fractures were located in the symphysis in one patient (16.7%), symphysis to parasymphysis in two patients (33.3%), parasymphysis in one patient (16.7%), and parasymphysis to the body in two patients (33.3%). Four patients (66.7%) had condylar head fractures, while two patients (33.3%) had single split fractures. The mechanism of trauma was a slip-down incident in four cases (66.7%), while two cases (33.3%) were caused by motorcycle traffic accidents. Four patients (67%) underwent intermaxillary fixation, while two patients (33%) improved with conservative treatment. Split fractures were diagnosed in all six patients on CT, whereas the fracture line was not clearly visible on panoramic images. Mandibular split fractures accounted for 5.6% of all mandibular fractures.Conclusion: This study provides insights into the clinical characteristics of rare mandibular split fractures and the diagnostic imaging findings. Furthermore, CT scans and three-dimensional image synthesis-instead of panoramic images-may be essential for accurately diagnosing mandibular fractures, including mandibular split fractures, in the future.
Optic foramen location on computed tomography
Authors: Nguyen Vuong Duc , Le Minh Tran Quang , Nguyen Chuong Dinh , Nguyen Tho Thi Kieu
Published: August 2023

Background: This study aimed to identify the location of the optic foramen in relation to the anterior sphenoid sinus wall, which is essential information for surgeons in planning and performing endoscopic transnasal surgery.Methods: Computed tomography scans of 200 orbits from 100 adult patients with no abnormalities were examined. The results included the location of the optic foramen in relation to the anterior sphenoid sinus wall and the distance between them, as well as the distance from the optic foramen and the anterior sphenoid sinus wall to the carotid prominence in the posterior sphenoid sinus.Results: The optic foramen was anterior to the anterior sphenoid sinus wall in 48.5% of orbits, and posterior in the remaining 51.5%. The mean distance from the optic foramen to the anterior sphenoid sinus wall was 3.82 ± 1.25 mm. The mean distances from the optic foramen and the anterior sphenoid sinus wall to the carotid prominence were 7.67 ± 1.73 and 7.95 ± 2.53 mm, respectively.Conclusion: The optic foramen was anterior to the anterior wall of the sphenoid sinus in approximately half of the orbits examined in this study, and posterior in the remaining half. The mean distance from the optic foramen to the anterior sphenoid sinus wall of the sphenoid sinus was 3.82 ± 1.25 mm.
Acute angioedema in Cape Town emergency centres and a suggested algorithm to simplify and improve management
Authors: Day C , Van der Walt J , Crombie K , Hendrikse C , Peter J
Published: August 2023

Background. Angioedema is the most common acute allergic presentation to emergency centres (EC), with hospitalisation rates increasing in high-income countries. Angioedema can complicate with life-threatening laryngeal obstruction. There are no local data; therefore, we aimed to characterise acute angioedema cases presenting to ECs and develop a simple management algorithm.
Objective. To characterise the clinical presentation, management and outcomes of acute angioedema cases presenting to ECs. Based on these findings, we developed a management algorithm for acute angioedema to improve the care of acute angioedema in South Africa (SA).
Methods. We conducted a retrospective folder review of all patients admitted to Groote Schuur Hospital (tertiary) and Mitchells Plain District Hospital (secondary) ECs from 1  June 2018 to 31  June 2020. Using ICD-10 coding, folders of adults ≥18 years with possible angioedema presenting to the ECs were screened. An allergist extracted demographics, medical history, management and outcome data for each angioedema event.
Results. A total of 142 acute angioedema episodes were included, with a median (interquartile range) age of 42 (28 - 58) years, and 62% of patients were female. The majority (124/142, 87%) of acute angioedema EC presentations involved swelling above the shoulders, with airway involvement in 20 (14%) patients, with two patients requiring intubation. Nineteen (13%) patients required admission, with five (26%) admitted to high care/intensive care. Drug-induced angioedema was the most common cause, with 64/142 (45%) linked to a known offending drug, 42/64 (65.6%) being angiotensin-converting enzyme inhibitor (ACE-I). Critical information to guide angioedema management, including past personal/family allergy history, and duration of angioedema prior to EC visit, was not recorded in 64.7% and 37.8% of EC records, respectively. Unnecessary treatment with corticosteroids or antihistamines occurred in 19/53 (36%) and 16/53 (30%) cases with bradykinin-mediated angioedema ACE-I angioedema and hereditary angioedema). Overall, only 36/142 (25%) of angioedema patients were connected to allergy care.
Conclusion. Angioedema is the most common allergy presentation to two ECs in Cape Town, SA. Bradykinin-mediated angioedema secondary to ACE-I therapy is the single most common offender, and was not appropriately managed in more than a third of cases. Based on these findings, we have developed a management algorithm that easily stratifies patients into bradykinin or mast cell-mediated angioedema with a step-by-step management approach that is applicable to the SA context. Ongoing awareness and education on allergy emergencies are required to ensure accurate diagnosis of less common causes of angioedema (particularly bradykinin-mediated angioedema) and linkage to allergy specialist care.
La distribución abductiva de valores en los catálogos digitales
Authors: Sans Pinillos Alger
Published: August 2023

Aunque ciertamente el auge de la IA, en general, y la transformación progresiva del paradigma analógico a la realidad virtual, en particular, han abierto nuevos e interesantes retos, también han redefinido los contextos desde los que tratar de comprender problemáticas clásicas. En este sentido, se retoma aquí la cuestión sobre la discriminación que acontece en la clasificación del patrimonio, tomando como punto de referencia la experiencia del museo virtual. En particular, se analiza la manera en que los valores socioculturales definen las categorías que luego se materializan en la catalogación de los objetos materiales u inmateriales expuestos.
Real Hypersurfaces in Nonflat Complex Space Forms with Reeb Recurrence Condition
Authors: Wang Yaning , Wang Pei
Published: August 2023

In this paper we prove that the structure Lie operator of a real hypersurface in a nonflat complex space form is Reeb recurrent if and only if it is Lie Reeb recurrent, and this is equivalent to that the hypersurface is of type (A).
Upper Triassic Peritidal Limestones from the Konyava Mountain, SW Bulgaria
Authors: Chatalov Athanas
Published: August 2023

Four microfacies are distinguished in the section of Tran Formation exposed near Viden peak. The bioclastic wackestones at the base are defined as low-energy, shallow subtidal sediments. The laminated mudstones were deposited in the intertidal/supratidal zone of a tidal flat where fine-grained carbonate was mainly accumulated by tidal currents along with some in-situ microbially induced precipitation. The mudstones with root casts and the massive mudstones are interpreted as deposits in intertidal/supratidal ponds and supratidal marsh (palustrine) areas where alternating wetting and drying periods locally favoured desiccation and pedogenesis with vegetation development. The interbedding of laminites with non-laminated mudstones was likely controlled by a combination of autogenic and allogenic processes. The ambient waters did not reach hypersalinity for early dolomitization because the landward part of the restricted peritidal setting was influenced by freshwater input under semi-arid climatic conditions. Another hypothesis presumes that the sedimentation occurred in a coastal wetland with influence of both freshwater and seawater. However, the peritidal interpretation is preferred herein because it more adequately explains the general depositional environment. The carbonate succession indicates an upward-shallowing trend and was formed during the final regressive phase of Triassic platform development in Carnian–Norian times.
First Palaeozoic Phyllocarid Crustaceans and Pterygotid Eurypterids in Serbia
Authors: Radonjić Miloš , Sachanski Valeri
Published: August 2023

Palaeozoic phyllocarid crustaceans and pterygotid eurypterids from the Gethicum Zone of Carpatho-Balkanides in Serbia are herein documented for the first time. The described and illustrated phyllocarid remains consisting of a coupled telson and furcal rami were collected from upper Silurian (?) shale. This specimen is fragmented and poorly preserved to allow identification to species level, and has thus been assigned to Ceratiocaris sp. indet. The eurypterids are represented by part of a fragment, showcasing the distinct scale-like ornamentation of the pterygotids, and a segment of a walking leg. The pterygotid remains were found together with a few graptolite taxa (Monograptus sudeticus Porębska, “M.” microdon microdon Reinh. Richter, Neomonograptus aequabilis (Přibyl), Uncinatograptus hercynicus (Perner), U. subhercynicus (Willefert)), which are characteristic for the lower part of the U. hercynicus graptolite zone (Lochkovian, Lower Devonian). There are at least two species in this stratigraphic interval that correspond to the pterygotid eurypterids remains from Serbia – Acutiramis perneri Chlupáč and Pterygotus cf. barrandei Semper, but without the chelicerae, it is impossible to make precise identification. These new finds from eastern Serbia, together with the Bulgarian ones, are a further confirmation of peri-Gondwanan origin of pre-Variscan Palaeozoic sediments in the West Srednogorie Unit in Bulgaria and in the Gethicum Unit in Serbia.
A 28/32/38 GHz Circularly Polarized DRA Micro-strip Antenna for 5G mm-Wave Applications
Authors: Kaitepalli Chandra , Kavitha Arunachalam
Published: August 2023

In modern communication system, mobile communication spectrum, below 3 GHz bands, faces more shortage and is not able to serve people with more efficient device connectivity and required data speed. Upon this background, 5G wireless communication – the 5th generation mobile technology standards are able to deliver high data rates, low latency communications, and massive device connectivity. For the efficient deployment of the 5G systems, and in order to support higher bandwidth, there is a dire need to design a compact and efficient antenna at mm wave frequencies (26/28 and 38). The resulting antenna, as the outcome, has been established to possess a compact size of 10 × 12 × 0.254 mm3 that covers three bands from the frequency spectra. The lower band resonant frequency is located at 26.74 GHz, the range between 25.44 GHz and 28.37 GHz, the middle band resonant frequency is located at 32 GHz, the range between of 31.08 GHz and 32.48 GHz, and the higher resonant frequency is located at 38.76 GHz, the range between 36.04 GHz and 40.34 GHz. In this article a modified novel structure of partial ground plane and DRA are used to get the better radiation enhancement and circular polarization. In this, the circularly polarized bands consist of the axial ratios <3 dB which are 27.95 GHz to 28.37 GHz, 31.08 GHz to 31.67 GHz, and 36.04 GHz to 38.73 GHz. The gain achieved is greater than 6.5 dBi and the efficiency is greater than 96% over the three bands. Ultimately, it is proved to the right option for 5G mm wave applications.
A Method by which circUBR1 Controls the Proliferation, Migration, and Invasion of HSC3 Cells
Authors: Yuan Ying , Xie Chuan , Wang Bohua , Hu Qian
Published: August 2023

This work investigates the effects of circUBR1 and the underlying mechanisms on the growth, migration and penetration of HSC3 cells derived from oral squamous carcinoma. The expression levels of circUBR1, miR-216a-3p and HSC3 were assessed in tissues from oral squamous cell carcinoma (OSCC) and adjacent tissues.

Based on the transfection targets, the cells were divided into four groups: si-NC, si-circUBR1, miR-NC, miR-216a-3p, si-circUBR1+anti-miR-NC and si-circUBR1+anti-miR-216a-3p. The cell viability, scratch healing rate, MMP-2 and MMP-9 expression, number of cell clones formed, and number of invasion cells were significantly lower in the miR-216a-3p group compared to the miR-NC group (p<0.05).

Moreover, when comparing the si-circUBR1+anti-miR-NC group to the si-circUBR1+anti-miR-216a-3p group, the cell viability, scratch healing rate, MMP-2 and MMP-9 expression, number of cell clones formed, and number of invasion cells were significantly higher in the si-circUBR1+anti-miR-216a-3p group (p<0.05). This suggests that disrupting circUBR1 expression leads to up-regulation of miR-216a-3p, resulting in reduced proliferation, clone formation, migration, and invasion of OSCC cells.
IQCH regulates spermatogenesis by interacting with CaM to promote RNA-binding proteins’ expression
Authors: Ruan Tiechao , Zhou Ruixi , Yang Yihong , Guo Junchen , Jiang Chuan , Wang Xiang , Shen Gan , Dai Siyu , Chen Suren , Shen Ying
Published: August 2023

IQ motif-containing proteins can be recognized by calmodulin (CaM) and are essential for many biological processes. However, the role of IQ motif-containing proteins in spermatogenesis is largely unknown. In this study, we identified a loss-of-function mutation in the novel gene IQ motif-containing H (
IQCH
) in a Chinese family with male infertility, characterized by a cracked flagellar axoneme and abnormal mitochondrial structure. To verify the function of IQCH,
Iqch
-knockout mice were generated by CRISPR-Cas9 technology which reproduced the human phenotypes. Mechanistically, IQCH can bind to CaM and then regulate the expression of RNA-binding proteins (especially HNRPAB), which are indispensable for spermatogenesis. Collectively, this study firstly unveiled the function of IQCH, expanded the role of IQ motif-containing proteins in reproductive processes, and provided important guidance for genetic counseling and gene diagnosis for male infertility.
Commensal Bacteria Maintain a Qa-1b-restricted Unconventional CD8+ T Population in Gut Epithelium
Authors: Guan Jian , Peske J. David , Manoharan Valerio Michael , Park Chansu , Robey Ellen A. , Sadegh-Nasseri Scheherazade , Shastri Nilabh
Published: August 2023

Intestinal intraepithelial lymphocytes (IELs) are characterized by an unusual phenotype and developmental pathway, yet their specific ligands and functions remain largely unknown. Here by analysis of QFL T cells, a population of CD8
+
T cells critical for monitoring the MHC I antigen processing pathway, we established that unconventional Qa-1
b
-restricted CD8
+
T cells are abundant in intestinal epithelium. We found that QFL T cells showed a Qa-1
b
-dependent unconventional phenotype in the spleen and small intestine of naïve wild-type mice. The splenic QFL T cells showed innate-like functionality exemplified by rapid response to cytokines or antigen, while the gut population was refractory to stimuli. Microbiota was required for the maintenance, but not the initial gut homing of QFL T cells. Interestingly, monocolonization with
Pediococcus pentosaceus,
which expresses a peptide that cross-activated QFL T cells, was sufficient to maintain QFL T cells in the intestine. Thus, microbiota is critical for shaping the Qa-1
b
-restricted IEL landscape.
Method Evaluations for Escherichia coli and Coliforms Detection in Northern New Jersey Water Bodies
Authors: Lee Lee H. , Wu Meiyin , Peri Alexandra , Chu Tin-Chun
Published: August 2023

Biological organisms can pose a threat to water quality and can be responsible for waterborne diseases. Because it is very expensive and time consuming to test for each pathogenic organism, coliform bacteria and E. coli, which originate in environmental and animal sources, serve as good pathogenic indicator organisms. This study focused on evaluation of water quality in New Jersey water bodies by monitoring both E. coli and coliform using different methods. Water samples were taken over two months at different sites. Three different methods used in this study are membrane filtration, PetrifilmTM and IDEXX methods to compare and determine which one or in combination methods are the most efficient and reliable way to identify and quantify bacterial contamination. It was concluded that areas that were highly urbanized, specifically high urban and agriculturally developed areas, had an increased level of contamination. Our study suggested that modified membrane filter method in combination of IDEXX Colilert® System provide the best results. Further research, such as Microbial Source Tracking (MST), will be conducted to identify the origin of fecal contamination.
Dynamic Characteristics of Periodic Motions in a Restricted N-Body Problem
Authors: Tsironis Christos S.
Published: August 2023

We investigate the existence and follow the evolution and dynamic stability of periodic motions in a restricted version of the N-body problem, where the positions of the mass bodies reside persistently on a planar polygon ring and its geometrical centre. The results show the existence of both (linearly) stable and unstable periodic orbits around the body placed on the ring centre (inside the ring), around all the periphery bodies (outside the ring) and around one or more of the periphery bodies. The stable periodic trajectories form regions of gravitational stability, whereas some classes of the unstable orbits exhibit bifurcations to non-symmetric periodic orbits of the same period, and less often period-doubling bifurcations.
Nutrient Supply Capacity Determination for Acid Soils Planted with Vegetables Using the Double Pot Technique
Authors: Tulin Anabella B. , Ranises Mechelle , Galambao Marciana B. , Umar Mohammed , Dorahy Chris G.
Published: August 2023

A double pot technique experiment was conducted to determine the nutrient supplying capacity of five acid soils planted with three vegetables such as cabbage (Brassica oleracea), maize (Zea mays) and tomato (Solanum lycopersicum L.). The soils used in the study were taken from Kibangay, Bukidnon; Mapayag, Bukidnon; Kapatagan, Davao del Sur; Claveria, Misamis Oriental and Cabintan, Leyte representing the acid soils of southern Philippines planted to vegetables. Results of the nutrient omission trials showed that the three vegetables tested have varying responses to five different soils as affected by nutrient availability. In most soils, regardless of vegetable planted, nitrogen (N) availability was the most critical nutrient affecting vegetable production followed by phosphorus (P) in the case of Cabintan and potassium (K) for Mapayag, Kibangay, Kapatagan and Claveria, respectively. This valuable diagnostic tool offers a cheap and simple method of assessing the nutrient supplying capacity of the various soils tested.
Treatment of High Strength Vegetable Processing Wastewater with a Sequencing Batch Reactor
Authors: Lam Ka Yee , Zytner Richard G. , Chang Sheng
Published: August 2023

The feasibility of an aerobic sequencing batch reactor was studied at the lab scale to treat the high organic loading present in two vegetable processing wastewaters. Hydraulic retention time (HRT) was varied to evaluate its effect on the removal efficiency of chemical oxygen demand (COD), total Kjeldahl nitrogen (TKN) and total phosphorus (TP). The results showed that a longer HRT promoted the removal of TP, while the liquid drawn per cycle had a larger effect on the COD removal efficiency. An increase in the COD/TKN and TKN/TP ratio decreased the removal efficiency of TKN and TP respectively. The optimized configuration was able to reduce the wastewater loadings to acceptable sewer discharge limits, making it possible eliminate the sewer surcharge fees.
Energy-Saving Periodic Flight at Transonic Speeds
Authors: Amouyal G. , Weihs D.
Published: August 2023

We examine possible energy saving by periodic changes in speed and altitude relative to steady state cruise, in the transonic regime. We develop a theoretical model of two-phase periodic flight with altitude variation in the transonic regime and compare it with a steady horizontal flight at the same average speed. The model predictions are verified by wind tunnel experiments. For example, by periodically accelerating from M=0.7 to M=1.1 while losing altitude, and then climbing back to the original height while decelerating, one can achieve savings of about 20% relative to steady flight at the same average speed and constant altitude.
Generic Story Problem Solution Template
Authors: Grogan Martin L.
Published: August 2023

Students routinely face homework and exam exercises presented as situational narratives requiring development of solutions that demonstrate grasp of concepts, relationships and analytical skills. This paper presents a “cookbook” style template that guides students through the solution process.
A wormhole attack detection method for tactical wireless sensor networks
Authors: Zhang Ke
Published: August 2023

Wireless sensor networks (WSNs) are networks formed by organizing and combining tens of thousands of sensor nodes freely through wireless communication technology. WSNs are commonly affected by various attacks, such as identity theft, black holes, wormholes, protocol spoofing, etc. As one of the more severe threats, wormholes create passive attacks that are hard to detect and eliminate. Since WSN is often used in the tactical network field, a planned secure network is essential for military applications with high security. Guard nodes are traffic monitoring nodes used to supervise neighbors’ data communication around the tactical networks. Therefore, this work proposes a Quality of Service (QoS) security mechanism to select multiple dual-layer guard nodes at different paths of the WSN based on the path qualities to detect wormholes. The entire network’s links are categorized into high, normal, and low priority levels. As such, this study aimed to confirm the security of high priority nodes and links in the tactical network, avoid excessive overhead, and provide random security facilities to all nodes. The proposed measures of the QoS-based security provision, including link cluster formation, guard node selection, authenticated guard node identification, and intrusion detection, ensure economic and efficient network communication with different quality levels.
Histological study of seventeen organs from dugong (Dugong dugon)
Authors: Kaewmong Patcharaporn , Jongjit Pathompong , Boonkasemsanti Araya , Kittiwattanawong Kongkiat , Kongtueng Piyamat , Matchimakul Pitchaya , Tangphokhanon Wasan , Pirintr Prapawadee , Khonmee Jaruwan , Buddhasiri Songphon , Piboon Promporn , Umsumarng Sonthaya , Mektrirat Raktham , Nganvongpanit Korakot , Pongkan Wanpitak
Published: August 2023

Background

Dugongs are marine mammals with a crescent-shaped tail fluke and a concave trailing margin that belong to the family Dugongidae., They are distributed widely in the warm coastal waters of the Indo-Pacific region. Importantly, the population of dugongs has decreased over the past decades as they have been classified as rare marine mammals. Previous studies have investigated the habitat and genetic diversity of dugongs. However, a comprehensive histological investigation of their tissue has not yet been conducted. This study provides unique insight into the organs of dugongs and compares them with other mammal species.

Methods

Tissue sections were stained with Harris’s hematoxylin and eosin Y. The histological structure of 17 organ tissues obtained from eight systems was included in this study. Tissue sections were obtained from the urinary system (kidney), muscular system (striated skeletal muscle and smooth muscle), cardiovascular system (cardiac muscle (ventricle), coronary artery, and coronary vein), respiratory system (trachea and lung), gastrointestinal system (esophagus, stomach, small intestine, liver, and pancreas), reproductive system (testis), lymphatic system (spleen and thymus), and endocrine system (pancreas).

Results

While most structures were similar to those of other mammal species, there were some differences in the tissue sections of dugongs when compared with other mammalian species and manatees. These include the kidneys of dugongs, which were non-lobular and had a smooth, elongated exterior resulting in a long medullary crest, whereas the dugong pyloric epithelium did not have overlying stratified squamous cells and was noticably different from the Florida manatee.

Discussion

Histological information obtained from various organs of the dugong can serve as an essential foundation of basal data for future microanatomical studies. This information can also be used as high-value data in the diagnosis and pathogenesis of sick dugongs or those with an unknown cause of death.