bluuebunny/crossref_metadata_2025 huggingface dataset:
Nationwide Seroprevalence of SARS-CoV-2 IgG Antibodies among Four Groups of Primary Health-Care Workers and Their Household Contacts 6 Months after the Initiation of the COVID-19 Vaccination Campaign in France: SeroPRIM Study Protocol
Authors: Pouquet Marie , Decarreaux Dorine , Prévot-Monsacré Pol , Hervé Corentin , Werner Andréas , Grosgogeat Brigitte , Blanché Hélène , Rabiega Pascaline , Laupie Julien , Kochert Fabienne , Abraham Nathalie , Sebaoun Jean-Marc , de Lamballerie Xavier , Charrel Remi , Souty Cecile , Camara Ibrahima , Pergeline Jeanne , Noël Harold , Guerrisi Caroline , Werf Sylvie van der , Carrat Fabrice , Hanslik Thomas , Blanchon Thierry , Falchi Alessandra
Published: July 2021

Background: The protocol study will focus on the seroprevalence of IgG antibodies to SARS-CoV-2 achieved by vaccination and/or natural protection as well as the history, symptoms, and risk factors for SARS-CoV-2 in four primary health-care workers (PHCWs) and their household contacts in metropolitan France. Methods: Here, we propose a protocol for a nationwide survey to determine the seroprevalence of IgG antibodies to SARS-CoV-2 achieved by vaccination and/or natural protection in four PHCW populations (general practitioners, pediatricians, pharmacists and assistants, and dentists and assistants) and their household contacts. Participants will be included from June to July 2021 (Phase 1) among PHCW populations located throughout metropolitan France. They will be asked to provide a range of demographic and behavioral information since the first SARS-CoV-2 wave and a self-sampled dried blood spot. Phase 1 will involve also a questionnaire and serological study of PHCWs’ household contacts. Seroprevalence will be estimated using two ELISAs designed to detect specific IgG antibodies to SARS-CoV-2 in humoral fluid, and these results will be confirmed using a virus neutralization test. This study will be repeated from November to December 2021 (Phase 2) to evaluate the evolution of immune status achieved by vaccination and/or natural protection of PHCWs and to describe the history of exposure to SARS-CoV-2.
Efficient CRISPR/Cas-Mediated Targeted Mutagenesis in Spring and Winter Wheat Varieties
Authors: Hahn Florian , Sanjurjo Loures Laura , Sparks Caroline A. , Kanyuka Kostya , Nekrasov Vladimir
Published: July 2021

CRISPR/Cas technology has recently become the molecular tool of choice for gene function studies in plants as well as crop improvement. Wheat is a globally important staple crop with a well annotated genome and there is plenty of scope for improving its agriculturally important traits using genome editing technologies, such as CRISPR/Cas. As part of this study we targeted three different genes in hexaploid wheat Triticum aestivum: TaBAK1-2 in the spring cultivar Cadenza as well as Ta-eIF4E and Ta-eIF(iso)4E in winter cultivars Cezanne, Goncourt and Prevert. Primary transgenic lines carrying CRISPR/Cas-induced indels were successfully generated for all targeted genes. While BAK1 is an important regulator of plant immunity and development, Ta-eIF4E and Ta-eIF(iso)4E act as susceptibility (S) factors required for plant viruses from the Potyviridae family to complete their life cycle. We anticipate the resultant homozygous tabak1-2 mutant lines will facilitate studies on the involvement of BAK1 in immune responses in wheat, while ta-eif4e and ta-eif(iso)4e mutant lines have the potential to become a source of resistance to wheat spindle streak mosaic virus (WSSMV) and wheat yellow mosaic virus (WYMV), both of which are important pathogens of wheat. As winter wheat varieties are generally less amenable to genetic transformation, the successful experimental methodology for transformation and genome editing in winter wheat presented in this study will be of interest to the research community working with this crop.
Typification and Taxonomic Remarks on Names of Iris (Iridaceae) Associated with the Turkish Flora
Authors: Boltenkov Eugeny V. , Güner Adil , Kuznetsov Alexander A.
Published: July 2021

In view of the forthcoming review of Turkish irises for Resimli Türkiye Florası (The Illustrated Flora of Turkey), nineteen names are typified or nomenclatural remarks are provided in the present report. Lectotypes are designated for Iris aschersonii, I. attica, I. bornmuelleri, I. purpureobractea (a taxonomic synonym of I. junonia), I. reticulata var. cyanea, I. reticulata var. sophenensis, I. suaveolens and I. taochia. The second-step lectotypification is made for I. histrio. Neotypes are designated for the names I. histrioides, I. junonia, I. masiae and I. reticulata var. histrioides; epitype, for the name I. reticulata var. sophenensis. For the previously typified names, I. bakeriana, I. musulmanica and I. reticulata, lectotypes are given. The lectotypes for I. histrio var. aintabensis, I. schachtii, and Xiphion danfordiae and the authorship for I. histrioides, are corrected. Images are provided for eight specimens selected as types that are not available online. Notes on distribution in Turkey are provided for all the accepted taxa.
Static and Dynamic Simulation of Single and Binary Component Adsorption of CO2 and CH4 on Fixed Bed Using Molecular Sieve of Zeolite 4A
Authors: Parinyakit Supatsorn , Worathanakul Patcharin
Published: July 2021

The simulation of carbon dioxide (CO2)-methane (CH4) mixed gas adsorption and the selectivity on zeolite 4A using Aspen Adsorption were studied. The influence of temperature ranging from 273 to 343 K, pressure up to 10 bar and various compositions of CO2 in the binary system were simulated. The findings of the study demonstrate that the models are accurate. In addition, the effects of various key parameters such as temperature, pressure, and various compositions of binary gases were investigated. The highest CO2 and CH4 adsorption are found at 273 K and 10 bar in the Langmuir isotherm model with 5.86 and 2.88 mmol/g, respectively. The amount of CO2 adsorbed and the selectivity of the binary mixture gas depends on the composition of CO2. The kinetics of adsorption for pure components of CO2 at high temperatures can reach saturation faster than CH4. The influence of the physical properties of zeolite 4A on kinetic adsorption were also studied, and it was observed that small adsorbent particles, large pore diameter, and large pore volume would enter saturation quickly. The prediction of CO2-CH4 mixed gas adsorption and selectivity on zeolite 4A were developed for further use for commercial gas separation.
Effects of Different Wall Shapes on Thermal-Hydraulic Characteristics of Different Channels Filled with Water Based Graphite-SiO2 Hybrid Nanofluid
Authors: Khetib Yacine , Alahmadi Ahmad , Alzaed Ali , Tahmasebi Ahamd , Sharifpur Mohsen , Cheraghian Goshtasp
Published: July 2021

In the current numerical study, various wall shape effects are investigated on the thermal-hydraulic characteristics of different channels filled with water-based graphite-SiO2 hybrid nanofluid. In this work, the performance evaluation criteria (PEC) index is employed as the target parameter to attain optimum geometry. Six different cases are studied in this research, and each case has different geometrical dimensions. The inlet temperature for the fluids in the channel is 300 K, over a range of different flow velocities. According to the obtained results, an increase in the volume fraction of nanoparticles results in higher PEC values. In addition, an increase in Reynolds number to Re = leads to an increase in the PEC index. The results clearly show that increasing the Reynolds number has two consequences: on the one hand, it increases the pressure drop penalty; on the other hand, it improves heat transfer. Therefore, the maximum value of the PEC index occurs at Re = 15,000.
Drone-Based Gamma Radiation Dose Distribution Survey with a Discrete Measurement Point Procedure
Authors: Molnar Andras , Domozi Zsolt , Lovas Istvan
Published: July 2021

A dose distribution map can be created using geographic information system (GIS) methods from sensor data that do not provide image information in a classical way. The results of discrete radiation measurements can be properly represented in a uniform raster above the surface. If the radiation measured at each site does not show a jump-like change, a dose distribution map can be prepared by interpolating the measured values. The coordinates of the measuring points can be used to calibrate the map. The calibrated and georeferenced map is suitable for locating hidden or lost radiation sources or for mapping active debris scattered during a possible reactor accident. The advantage of the developed method is the measurement can be performed with a small multicopter, cost-effectively, even without human intervention. The flight time of small multicopters is very limited, so it is especially important to increase the efficiency of the measurement. During the experiments, a practical comparison of several methods was made with regard to the measurement procedure. Similarly, based on the measurement experience, the detector system was further developed and tested in three main steps. A system was developed with a detector system with a total weight of 500 g, including a battery capable of operating the detector for at least 120 min. The device is capable of detecting an average of 30 events/min at of 0.01 μSv/h background radiation. Experiments have shown that the system is able to significantly detect a source with an activity of 300 μSv/h by scanning above 10 m ground level.
Ecotypic Morphological and Physio-Biochemical Responses of Two Differentially Adapted Forage Grasses, Cenchrus ciliaris L. and Cyperus arenarius Retz. to Drought Stress
Authors: Ghafar Muhammad Adeel , Akram Nudrat Aisha , Saleem Muhammad Hamzah , Wang Jianyong , Wijaya Leonard , Alyemeni Mohammed Nasser
Published: July 2021

Crop performance and yield are the results of genotypic expression as modulated by continuous interaction with the environment. Among the environmental aspects, drought and salinity are the most important factors, which limit the forages, including grasses, on a global basis. Grass species have the ability to grow under low water conditions and can produce high dry yield, proteins, and energy in areas exposed to drought stress. For this purpose, we conducted the present study to understand the response of forage grasses under drought stress from two different regions (Salt Range and Faisalabad) of Punjab, Pakistan. Two ecotypes of each grass species (Cenchrus ciliaris L. and Cyperus arenarius Retz.) were grown in pots at the botanical research area, Government College University Faisalabad, Pakistan. A group of plants were subjected to drought stress (60% field capacity) and controlled (100% field capacity) after three weeks of seed germination. The results from the present study depicted that the fresh and dry weights of root and shoot were decreased significantly under drought conditions. Moreover, C. ciliaris of the Salt Range area showed more resistance and higher growth production under drought stress. The chlorophyll (a and b) contents were also decreased significantly, while MDA, total soluble sugars, and proline levels were increased significantly under water-limited environments in the C. arenarius of Salt Range area. Enzymatic antioxidants (superoxidase dismutase (SOD) and peroxidase (POD)) and leaf Na+ were significantly raised in C. arenarius under drought stress collected from the Faisalabad region. Cenchrus ciliaris showed higher level of H2O2, total soluble proteins, glycinebetaine, catalase (CAT) and POD compared to C. arenarius. It also retained more leaf and root Ca2+, and root K+ under drought stress. It was concluded from the study that C. ciliaris is more resistant to drought in biomass production collected from the Salt Range area. The results suggested that C. ciliaris can be more widely used as a forage grass under water-scarce conditions as compared to C. arenarius.
Mutation E48K in PB1 Polymerase Subunit Improves Stability of a Candidate Live Attenuated Influenza B Virus Vaccine
Authors: Mo Jongsuk , Cardenas-Garcia Stivalis , Santos Jefferson J. S. , Ferreri Lucas M. , Cáceres C. Joaquín , Geiger Ginger , Perez Daniel R. , Rajao Daniela S.
Published: July 2021

Influenza B virus (IBV) is a major respiratory pathogen of humans, particularly in the elderly and children, and vaccines are the most effective way to control it. In previous work, incorporation of two mutations (E580G, S660A) along with the addition of an HA epitope tag in the PB1 segment of B/Brisbane/60/2008 (B/Bris) resulted in an attenuated strain that was safe and effective as a live attenuated vaccine. A third attempted mutation (K391E) in PB1 was not always stable. Interestingly, viruses that maintained the K391E mutation were associated with the mutation E48K. To explore the contribution of the E48K mutation to stability of the K391E mutation, a vaccine candidate was generated by inserting both mutations, along with attenuating mutations E580G and S660A, in PB1 of B/Bris (B/Bris PB1att 4M). Serial passages of the B/Bris PB1att 4M vaccine candidate in eggs and MDCK indicated high stability. In silico structural analysis revealed a potential interaction between amino acids at positions 48 and 391. In mice, B/Bris PB1att 4M was safe and provided complete protection against homologous challenge. These results confirm the compensatory effect of mutation E48K to stabilize the K391E mutation, resulting in a safer, yet still protective, IBV LAIV vaccine.
Regular Healthcare Provider Status Does Not Moderate Racial/Ethnic Differences in Human Papillomavirus (HPV) and HPV Vaccine Knowledge
Authors: Amboree Trisha L. , Sonawane Kalyani , Deshmukh Ashish A. , Montealegre Jane R.
Published: July 2021

Background: Racial/ethnic minorities generally have a lower knowledge of human papillomavirus (HPV) and the HPV vaccine than non-Hispanic Whites. They are also less likely to have a regular healthcare provider (HCP). Given the role of HCPs in disseminating health information, we evaluated whether racial/ethnic disparities in HPV knowledge are moderated by regular HCP status. Methods: Data from the Health Information National Trends Survey Five (HINTS 5) Cycles One and Two (2017–2018) were analyzed. HPV and HPV vaccine knowledge were compared by regular HCP status across race/ethnicities. Independent partially-adjusted multivariable logistic regression models were used to assess the association between race/ethnicity and knowledge after controlling for sociodemographic characteristics. The resulting adjusted odds ratios were compared to those from fully-adjusted models that included HCP status. Results: After adjusting for regular HCP status, differences in knowledge persisted between racial/ethnic groups. Compared to Whites, Hispanics and Other race/ethnicities had significantly lower odds of having heard of HPV. Blacks, Hispanics, and Other race/ethnicities had significantly lower odds of having heard of the HPV vaccine. Conclusion: Racial/ethnic minorities had significantly lower levels of knowledge despite HCP status. These data suggest the need to address disparities in health information and strengthen provider–patient communication regarding HPV and the HPV vaccine.
“Remote working” legal integration: practice issues and development prospects
Authors: Salikova N. M. , Batukhtina E. M.
Published: July 2021

The article is dealing with some issues of legal regulation of remote working, which extensive application was caused by the pandemic. Authors analyze the legislation, concerning distance working, as well as the introduced law “On Introducing Amendments to The Labor Code of the Russian Federation, in relation to distance and remote work”. As a result of the research a set of questions for the legislator is posed. Furthermore, certain improving the introduced law proposals based upon detected collisions and contradictions of the legal writing, are framed in the article.
Employment Through Intermediary Agencies During the Spread of Coronavirus Infection: Legal Aspects
Authors: Shuvalova I. A.
Published: July 2021

The article deals with intermediary employment agencies. The stages of employment are analyzed with the help of the state employment service and private employment agencies. Some problems are identified in the transition to remote provision of services by intermediary agencies and in terms of payment of unemployment benefits during the spread of coronavirus infection on the territory of the Russian Federation. Some ways to solve them are suggested.
Gamification in intracorporate training
Authors: Ochakovskaya Vera Andreevna
Published: July 2021

The article presents a draft scenario for intracorporate training. The training can be organized both offline and online. The training scenario is stylized after the book by J.K. Rowling «Harry Potter». In this case, stylization acts as an effective tool for the organization of intracorporate training and a socio-game space.
Remote (remote) work: some aspects of legal regulation and enforcement
Authors: Sokolenko N. N. , Mkrtchyan A. L.
Published: July 2021

The onset of the Covid-19 pandemic, due to objective circumstances, led to a large-scale spread of the mode of work outside stationary workplaces, to the development of interaction between the parties to labor relations using information and communication technologies. So, the contradictions between the real processes in the world of work during the pandemic and Russian labor law were revealed.
The travelling nature of the work
Authors: Rachenkova Yu.A.
Published: July 2021

The company plans to hire an engineer to work in the territory of the Russian Federation, in the labor contract indicating the condition — the traveling nature of the work. In the material, the author will answer the questions: Does the employee need to pay daily subsistence allowance in such working conditions? What documents should be used by the accountant to accept documents for residence, travel? Do I need to issue a travel certificate? How do I keep a record of working hours for such an employee?
Social assessment of children dental health and its determining factors
Authors: Svetlichnaya T. G. , Mityagina A. S. , Burkova T. M. , Ogorelkova N. M.
Published: July 2021

Relevance.The high prevalence of tooth decay requires investigation of its risk factors. The aim was to study tooth decay risk factors among six-year-old children according to the level of dental health (based on parents’ assessment).Materials and methods.The research evaluated the dental health of six-year-olds and factors defining their oral health; The study surveyed 515 parents of six-year-old children from 7 kindergartens in Arkhangelsk. Pearson chi-square test assessed the differences in the frequency of tooth decay factors among six-year-old children according to the level of dental health. The accepted significance level was 0.05.Results.The Arkhangelsk parents evaluated the dental health of their six-year-olds as relatively favourable: good (41.2%) and satisfactory (46.6%). Only 9.5% of children had poor health. Children generally had good oral hygiene skills: 86.8% liked brushing their teeth; 60.2% squeezed the optimal amount of toothpaste on the toothbrush; 56.7% brushed their teeth twice a day. The dental literacy of parents was satisfactory: 67.0% purchased toothpaste for children; 90.8% considered necessary to treat primary teeth; 69.2% replaced toothbrush every three months; 59.7% visited a pediatric dentist twice a year. The children with poor dental health had insufficient oral hygiene skills: 46.9% did not like teeth cleaning; 51.1% brushed their teeth once a day. Their diet was not healthy: 100.0% did not eat hard food; 65.3% frequently consumed sweets. The parents  of children with poor dental health had low medical literacy and poor oral hygiene: 46.9% did not know that treatment of primary teeth was necessary; 42.9% considered the treatment of primary teeth as unnecessary; 32.6% purchased whatever toothpaste. The general negative trend is to use toothpaste without fluoride (68.1%).Conclusions.The results of the study demonstrated a significantly higher frequency of cariogenic factors in children with poor dental health.
Clinical experience of using the tooth positioner in the treatment of patients with malocclusion
Authors: Simakova A. A. , Gorbatova L. N. , Dracheva N. V. , Muzgin D. O.
Published: July 2021

Relevance. The treatment of the early signs of pathology at a younger age is more favourable than its correction at the later stage of development. Aim – to analyze the literature and demonstrate the experience of clinical application of a silicone tooth positioner in the treatment of patients with malocclusion.Materials and methods. The study analyzed the records and clinical cases of 50 patients. The measurements on the study models were taken and patients’ photos were analyzed.Results. The study revealed positive treatment results which confirmed the effectiveness of the “Corrector” tooth positioner in treating the malocclusion in different planes as well as retaining the tooth position.Conclusions. Individually fit “Corrector” tooth positioner has confirmed its effectiveness and proved to be an appliance of choice for prevention, active treatment or retention stages of the orthodontic treatment.
Gilda de Mello e Souza
Authors: Fiori Arantes Otília Beatriz , Arantes Paulo Eduardo
Published: July 2021

Os quatro ensaios que compõem este livro procuram dar conta do que se poderia chamar de “método” do ensaísmo crítico de Gilda de Mello e Souza. Muito embora a nota específica de sua prosa de ensaio não se reduza a uma questão de método, não seria exagero caracterizar seu estilo como uma variante altamente elaborada daquilo que o historiador Carlo Ginzburg chamou de “método indiciário”, que por sua vez entronca na linhagem que Lionello Venturi reabilitou na figura do perito-conoscitore. Na esteira do desinteresse pela teoria, típico do grupo Clima, Gilda muito cedo percebeu “a importância desse exercício crítico minucioso, paciente, centrado na observação das características mais insignificantes”. Uma amostra exemplar deste procedimento encontra-se no ensaio sobre a crítica cinematográfica de Paulo Emílio Sales Gomes, que ela interpreta como um singularíssimo exercício de perícia detetivesca. Pois é essa mesma abordagem indiciária que lhe permite reconhecer em Almeida Jr. o pintor que pela primeira vez revela em suas telas o “homem brasileiro”, inaugurando um novo ciclo da pintura no Brasil, que até então obedecia aos esquemas herdados do academicismo europeu na representação dos temas nacionais. Deixando-se levar por sua própria experiência de menina do interior, mas sobretudo, pelo olhar educado no estudo das técnicas corporais descritas em sua tese sobre a Moda no Século XIX, Gilda foi assim capaz de identificar essa figura, à margem dos esquemas culturais importados, através dos mínimos indícios e sinais presentes em todo um ritual de gestos e posturas corporais das figuras do pintor ituano. Com isso, algo como a formação da pintura brasileira por assim dizer despontava no horizonte, culminando no Modernismo, para depois se desdobrar em outras configurações, como nos casarios dos pintores da Escola Paulista, chegando até às cidades esvaziadas de um Gregório Gruber. A dívida de Gilda para com os mestres “amadores” franceses (Jean Maugüé, Lévy-Strauss e Roger Bastide) é recapitulada no último ensaio. Ao final, encerrando esse volume, um trecho de uma entrevista de Otília Arantes, dada em 2016, por ocasião dos dez anos de morte de Gilda de Mello e Souza.
Palavras-chave: Gilda de Mello e Souza, Estética, Crítica de Arte, História da Arte, Artes Plásticas, Pintura, Moda, Formação, Almeida Jr., Mário de Andrade, Gilberto Freire, O homem brasileiro, O maleiteiro, Dinâmica dos gestos, Século XIX, Eliseu Visconti, Mário Pedrtosa, Tarsila do Amaral, Família Paulista, Gregório Gruber, Ensaismo, Carlo Guinzburg, Método indiciário, Gombrich, Estrutura relacional, Leonello Venturi, Grupo Clima, Jean Maugüé, Lévy Strauss, Roger Bastide, Crítica de Amador
ARTIFICIAL INTELLIGENCE FOR TELECOMMUNICATION NETWORKS
Authors: БОРОДИН А.С. , ВОЛКОВ А.Н. , МУТХАННА А.С. , КУЧЕРЯВЫЙ А.Е.
Published: July 2021

Исследуется возможность применения искусственного интеллекта (ИИ) в сетях связи. Рассматриваются достижения в этом направлении исследований, а также анализируются рекомендации Сектора стандартизации телекоммуникаций Международного союза электросвязи (МСЭ-Т). Сформулированы перспективные направления работ в области ИИ для сетей связи.

The paper analyzes artificial intelligence use cases in telecommunication networks. Achievements in this area of research are reviewed, and recommendations of the TelecommunicationStandardization Sector oftheInternational Telecommunication Union (ITU-T) are analyzed. Based on the analysis, promising directions of research in the field of artificial intelligence for telecommunication networks are formulated.
El trabajo de cuidado no remunerado en Salud en el contexto de América Latina. La centralidad durante la crisis de COVID-19
Authors: Pautassi Laura
Published: July 2021

El cuidado en salud asume características específicas, complejas y de alta demanda, que forman parte de un tratamiento médico, de un acto posquirúrgico o del acompañamiento en enfermedades crónicas, discapacidad o afecciones a la salud mental. Estos cuidados, principalmente a cargo de las mujeres, se encuentran invisibilizados y no han sido incorporados por las políticas y acciones estratégicas de salud. La evidencia empírica muestra que brindar cuidados en salud impacta directamente en la autonomía y calidad de vida de las cuidadoras, dado que afecta su salud física y psicológica. En el contexto de la pandemia provocada por la COVID-19, el artículo recorre las principales definiciones del trabajo no remunerado en salud (TnRS). Si bien dicho relevamiento en torno al TnRS es mas amplio (período 2000-2020), el artículo se concentra en el tratamiento de la pandemia en América Latina. La metodología utilizada es de tipo cualitativo, en base a un enfoque de género y de derechos, que permite identificar la estructura de poder asimétrica que requiere ser transformada mediante acciones transversales y en base a la interdependencia de derechos humanos. Las conclusiones presentan aprendizajes y propuestas de políticas públicas para el reconocimiento del TnRS y su necesaria distribución.
El pasado reciente argentino y las normativas escolares
Authors: Papier Viviana
Published: July 2021

Desde la formación de los estados nacionales la escuela ha sido un espacio de transmisión de determinados relatos sobre el pasado y de construcción de memoria colectiva. El pasado reciente argentino en particular, caracterizado como un “pasado que no pasa”, controvertido, traumático y conflictivo, es necesariamente “reelaborado” por la institución escolar para transmitirlo a los jóvenes.

En este artículo realizo un breve recorrido teórico sobre el pasado reciente como objeto de estudio, reconociendolas principales conceptualizaciones y discusiones acerca de la memoria, la historia y la educación, por un lado, para luego analizar las diferentes narrativas que se han construido acerca del pasado reciente argentino tanto desde la historia como desde la memoria y las modalidades con las que se propone incorporar en la escuela a través de las reformas educativas y los diseños curriculares de la materia Historia de 5to año y 6to año del nivel secundario de la Provincia de Buenos Aires.
Sosialisasi Pemanfaatan Daun Sirih Di Desa Sambiroto, Kec. Baron Sebagai Obah Dari Kemu
Authors: Megasari Nur Septiani , Sadewo Fransiscus Xaverius Sri
Published: July 2021

Penelitian ini dilatar belakangi karena banyaknya pengangguran di Desa Sambiroto yang disebabkan karena pandemic covid-19. Selain itu karena belum pernah diadakannya sosialisasi mengenai pemanfaatan daun sirih sebagai obat herbal yang dikemas dalam kapsul. Penelitian ini dilakukan untuk dapat mengetahui bagaimana sosialisasi pemanfaatan daun sirih sebagai obat herbal yang dikemas dalam kapsul di Desa. Sambiroto, Kecamatan Baron. Adapun tujuannya untuk menganalisis pemanfaatan daun sirih di Desa. Sambiroto, Kecamatan Baron sebagai Obat Herbal yang dikemas dalam kapsul. Serta dapat mengembalikan perekonomian masyarakat menjadi lebih baik, dengan demikian kegiatan ini tidak lepas dari dukungan dari pihak desa dan masyarakat sendiri. Dalam penelitian ini metode yang digunakan yaitu kualitatif dengan pendekatan fenomenologi. Pendekatan yang dilakukan ini bersifat deskriptif, yakni dengan penyajian data dan format deskriptif, dengan tujuan untuk menggambarkan, meringkas dari hasil data yang telah didapatkan. Hasil dalam penelitian ini adalah bahwa peneliti merancang berbagai kegiatan yang digunakan untuk melakukan pemanfaatan daun sirih sebagai sebagai obat herbal untuk masayarakat Desa Sambiroto, Kec. Baron di masa pandemi covid-19.
Memasyarakatkan Tanya 5O Dan Efek Interaksi Obat Pada Siswa MTsN 2 Kota Palangka Raya
Authors: Mashar Harlyanti Muthma'innah , Normila Normila , Ramadhani Juni , Dali Dali , Ismail Ismail
Published: July 2021

Pengabdian masyarakat ini merupakan salah satu bentuk sharing program Kerjasama dari Kementerian Kesehatan RI dan Dinas Kesehatan Provinsi dan Kota yaitu GeMa CerMat (Gerakan Masyarakat Cerdas Menggunakan Obat) yang salah satu programnya adalah melalui promosi tagline “Tanya Lima O”. Melalui tagline ini diharapkan masyarakat dapat lebih aktif lagi dalam mencari informasi tentang obat, tidak hanya pada tenaga kesehatan, namun juga dapat diperoleh dari sumber lain yang valid dan dapat dipercaya. Selain informasi tersebut, masyarakat juga perlu mengetahui interaksi obat, khususnya interaksi obat dengan makanan. Demi tercapainya penggunaan obat yang bermutu dan aman, keterlibatan masyarakat secara aktif sangat diharapkan. Pada kegiatan ini yang menjadi khalayak sasaran adalah siswa di MTsN 2 Palangka Raya. Metodenya berupa pelaksanaan posttest dan pretest, penyuluhan interaktif dengan para, serta diskusi dan tanya jawab. Nilai yang didapatkan dari hasil posttest dan pretest kemudian dilakukan uji statistik menggunakan paired T-test dan uji Gain. Berdasarkan hasil analisis diperoleh hasil bahwa terdapat perbedaan pengetahuan yang bermakna antara sebelum dan sesudah penyuluhan diberikan. Hal ini dibuktikan dengan terjadinya peningkatan nilai posttest. Rata-rata nilai posttest adalah 80, dan nilai ini lebih besar dari pada nilai rata-rata pretest yaitu 44. Hasil analisis dengan paired T-test diperoleh nilai p=0,000 yang menunjukkan bahwa terdapat perbedaan pengetahuan yang bermakna antara sebelum dengan sesudah penyuluhan. Nilai pemahaman yang meningkat setelah diberikan penyuluhan ditunjukkan dengan persentase 87,69%, terdiri dari yang memperoleh nilai gain tinggi sebanyak 25 orang (38,46%) dan nilai gain sedang sebanyak 32 orang (49,23%).
Providing new impetus to corporate well-being programmes: improving life expectancy through risk assessment
Authors: Vona Gábor
Published: July 2021

Diseases of the circulatory system are leading causes of death, which compel stakeholders to lessen cardiovascular risks by utilising more effective prevention. These risks can be estimated based on gender, age, smoker status, systolic blood pressure, and total cholesterol. Artificial neural networks enable modelling of 10-year cardiovascular mortality rates. Understandable communica-tion of potential gains in life expectancy may enhance health consciousness through mitigating behavioural risks. The reproduction of death statistics requires the adjustment of the recommended probabilities for the occurrence of fatal cardiovascular events. This study deals with countries at high and low cardiovascular risk, selecting Hungary and the Czech Republic (high risk) and Austria (low risk). In Hungary, the gains in life expectancy are (43.4 – 36.2 =) 7.21 years for fe-males and (37.4 – 28.0 =) 9.4 years for males, both aged 40. These figures moderate to (21.2 – 15.6 =) 5.72 and (17.1 – 11.3 =) 5.8 years for elderly people aged 65, respectively. The Czech Republic represents an interim phase between the two other countries regarding ad-vancement in life expectancy, the respective gains exceed the Hungarian values: (45.8 – 37.8 =) 8.0, (39.7 – 29.7 =) 10.0, (23.0 – 16.6 =) 6.4, and (18.2 – 12.3 =) 5.9 years. In contrast, a 40-year-old woman may benefit from an additional (46.6 – 41.3 =) 5.3 years in Austria, while the corresponding accrual for men is (42.3 – 35.7 =) 6.6 years. On reaching 65 years, the increment is (23.4 – 19.3 =) 4.1 and (20.0 – 16.1 =) 3.9 years.
Judicial Reform of 1864 and Its Impact on the Russian Legal System
Authors: Levin V. V.
Published: July 2021

The article is about the fact that as a result of the judicial reform of 1864, criminal proceedings were fundamentally transformed. The first time the independence of the courts and the transparency of judicial investigations were proclaimed, the institutions of the bar and jurors were introduced, and a number of procedural guarantees were established for the accused and defendants, including in relation to criminal and political cases.
Challenges and Threats to Russian Society in the Context of the Pandemic: Problems and Directions of Ensuring Social Security
Authors: Margulyan Ya. A. , Danilova N. I.
Published: July 2021

In the context of the COVID-pandemic and the global economic crisis, qualitatively new global and national social challenges and threats are being formed. The scientific analysis of their state, destructive influence on political, economic and social processes in society, allows to formulate the directions and mechanisms of ensuring social security of the Russian society.
On the Implementation of International Law in the Constitutional Legal System of Russia: Theory and Practice
Authors: Mishalchenko Yu. V. , Bugel’ N. V. , Egorova E. L.
Published: July 2021

Implementation of international law at the national level continues to be an actual direction for both theoretical and practical studies. Within the framework of the processes of globalization and integration, this issue is of particular importance. This article examines the theoretical aspects of the implementation of International Law in the constitutional legal system, as well as the features of the practice of making decisions by the European Court of Human Rights in modern conditions. The influence of sociocultural processes taking place in Western European countries on the interaction of national and international legal order. The purpose of the work is to analyze the theoretical and practical aspects of the implementation of International Law in the national legal system within the framework of integration processes that have a direct impact to the main spheres of society. In the course of the research have been used: formal logical and technical-legal methods. The authors made a number of conclusions about the modern mechanism of interaction between the national and international legal order.
PACIENTŲ, PATYRUSIŲ SPONTANINĘ INTRASMEGENINĘ KRAUJOSRUVĄ, PERIFERINIO KRAUJO LEUKOCITŲ SĄSAJA SU LIGOS BAIGTIMI
Authors: Kakta Benas , Grygalytė Lolita , Tamošuitis Tomas , Balčiūnienė Neringa
Published: July 2021

Tikslas. Įvertinti pacientų, patyrusių spontaninę intrasmegeninę kraujosruvą (ISK), periferinio kraujo leukocitų ir jų populiacijų ryšį su ligos baigtimi.

Metodika. Atlikta retrospektyvinė 74 pacientų, gydytų Lietuvos sveikatos mokslų universiteto ligoninės Kauno klinikų (LSMUL KK) Neurochirurgijos intensyvios terapijos skyriuje (NITS) 2018-2019 m. dėl patirtos spontaninės ISK, ligos istorijų analizė. Analizuoti tiriamųjų demografiniai rodikliai, periferinio kraujo leukocitai ir jų populiacijos, Glasgow komų skalės (GKS) įverčiai, ISK tūriai bei ligos baigtis.

Rezultatai. Mirusių pacientų leukocitų, neutrofilų skaičius bei neutrofilų ir limfocitų santykis (NLS) buvo didesni, nei išgyvenusių (p<0,05). Atlikus tiesinę regresiją nustatyta, kad didesnis NLS siejasi su didesniu ISK tūriu (β=1,887, koreg. R2=0,051, p=0,03), tuo tarpu su mažesniu GKS įverčiu susijęs didesnis bendras leukocitų skaičius (β=-0,298, koreg. R2=0,062, p=0,018) ir absoliutus neutrofilų skaičius (β=-0,308, koreg. R2=0,064, p=0,017). Atlikus logistinę regresiją nustatyta, kad su didesne mirties tikimybe susijęs didesnis bendras leukocitų (GS=1,156, p=0,031), absoliutus neutrofilų skaičius (GS=1,167, p=0,024) ir NLS (GS=1,091, p=0,028).

Išvados. Didesnis periferinio kraujo leukocitų skaičius susijęs su mažesniu GKS įverčiu ir didesne mirties tikimybe. Didesnis neutrofilų skaičius siejasi su mažesniu GKS įverčiu ir didesne mirties tikimybe, o didesnis NLS susijęs su didesniu ISK tūriu ir didesne mirties tikimybe.
DIABETINĖS KETOACIDOZĖS GYDYMO IR BAIGTIES ASPEKTAI
Authors: Adukauskienė Dalia , Jokūbonienė Laura , Kazėnaitė Edita , Mašanauskienė Edita , Gečionienė Auksė
Published: July 2021

Tyrimo tikslas – ištirti dažnos endokrininės patologijos – diabetinės ketoacidozės (DKA) kaip cukrinio diabeto (CD) dekompensacijos gydymo komplikacijas, jų etiologiją bei sąsają su gydymo intensyviosios terapijos skyriuje (ITS) trukme, ir, remiantis tyrimo duomenimis, suteikti konkrečias galimybes klinicistams optimizuoti gydymo taktiką ir su tuo susijusias gydymo baigtis.

Metodika. Atlikta retrospektyvinė kohortinė studija. Imtis – 120 pacientų, gydytų dėl DKA tretinio lygio universitetinės ligoninės ITS 6 metų periodu. Bioetikos centro leidimas (Nr. BEC – MF – 492). Tirtos DKA gydymo komplikacijos bei natrio bikarbonato naudojimas ir jų sąsaja su gydymo trukme ITS. Statistiniams skaičiavimams naudota SPSS 23.0 paketo versija. Požymiai vertinti kaip statistiškai reikšmingi, kai p < 0,05.

Rezultatai.Nustatytos dažniausios DKA priežastys: piktnaudžiavimas alkoholiu (29 %), ūminė infekcija (28 %), insulino vartojimo sutrikimai (28 %), sunkios gretutinės ūminės ligos (5 %), neaiškios (10 %). DKA gydymo metu hipokalemija diagnozuota 53 proc. pacientų, gydymo ITS trukmė 52,9 ± 29,7 vs 32,8 ± 18,6 val., p < 0,05. Skiriant gydymą insulinu, hipoglikemija diagnozuota 18 proc. atvejų, gydymo ITS trukmė 63,2 ± 38,5 vs 38,9 ± 21,2 val., p < 0,05. Hipoglikemijos ar normoglikemijos atvejais, išliekant ketoacidozei, insulin skyrimas klaidingai nutrauktas 33 proc. pacientų, gydymo ITS trukmė 56,5 ± 30,7 vs 37,0 ± 22,5 val., p<0,05. Simptominiam ketoacidozės gydymui esant stabiliai hemodinamikai natrio bikarbonato tirpalai paskirti 28 proc. pacientų, gydymo ITS trukmė 55,2 ± 27,5 vs 39,1 ± 25,6 val., p< 0,05. Bendra DKA gydymo ITS trukmė 9 – 163 (45,1±34,2) val.: dėl infekcijos 19 – 163 (61,7 ± 41,0), neinfekcinių priežasčių 9 – 97 (31,6 ± 19,4) val., p < 0,05.

Išvados. Piktnaudžiavimas alkoholiu, ūminė infekcija bei insulino dozavimo pažeidimas – priežastys, predisponavusios diabetinę ketoacidozę. Hipokalemija, hipoglikemija, ankstyvas insulino nutraukimas, išliekant ketoacidozei, natrio bikarbonato skyrimas nustatyti kaip diabetinės ketoacidozės gydymo komplikacijos, ilginusios gydymo trukmę intensyviosios terapijos skyriuje. Infekcinės komplikacijos dvigubai ilgino gydymo intensyviosios terapijos skyriuje trukmę.
VIRŠŪNINIŲ DANTŲ ŠAKNŲ REZORBCIJOS PALYGINIMAS, GYDANT LIGATŪRINIAIS IR BELIGATŪRINIAIS BREKETAIS
Authors: Labutytė Kristė , Berlin Vilija
Published: July 2021

Išorinė viršūninė šaknies rezorbcija yra dažna ortodontinio gydymo komplikacija, lemianti danties šaknies struktūros praradimą ir šaknies ilgio sutrumpėjimą. Išorinė viršūninė šaknies rezorbcija dažniausiai diagnozuojama viršutinio žandikaulio kandžiuose. Tyrimo tikslas – išanalizuoti ir palyginti ortodontinio gydymo ligatūriniais ir beligatūriniais breketais įtaką viršūninės dantų šaknų rezorbcijos atsiradimui. Šioje sisteminėje apžvalgoje išanalizuoti 4 viso teksto moksliniai straipsniai, atitikę atrankos kriterijus. Remiantis išanalizuotų straipsnių rezultatų duomenimis, išorinė viršūninė dantų šaknų rezorbcija stebima gydant ir ligatūriniais, ir beligatūriniais breketais. Palyginus išorinės viršūninės dantų šaknų rezorbcijos sunkumo laipsnį tarp ligatūriniais ir beligatūriniais breketais gydomų pacientų, rezultatai tarp grupių statistiškai reikšmingai nesiskiria.
ORGANINIO DELYRO HIPODIAGNOSTIKA: DIAGNOSTIKOS PERSPEKTYVOS LIETUVOJE
Authors: Kersnauskaitė Džiugilė , Kirtiklytė Rusnė , Navickas Petras , Šerpytis Pranas , Navickas Alvydas
Published: July 2021

Lietuvoje stebima delyro hipodiagnostikos problema, kurią aiškinti būtų galima bendrosios delyro diagnozavimo taktikos, kurią galėtų taikyti įvairių specialybių gydytojai, nebuvimu. Yra nemažai standartizuotų diagnostikos ir atrankos skalių, kurios naudojamos nustatant delyro diagnozę.

Tyrimo tikslas. Išanalizuoti validuotus delyro atrankos ir diagnostikos metodus, plačiausiai taikomus klinikinėje praktikoje.

Tyrimo metodika. Atlikta 11 delyro atrankos ir diagnostikos metodų apžvalga; atrinkti metodai lyginti vieni su kitais pagal skalės paskirtį, jautrumą, specifiškumą, vertintoją, vertinimo trukmę ir skalėje vertinamus parametrus. Rezultatai. Iš 11 atrinktų skalių daugiausiai informacijos radome apie NEECHAM (95-97,2% jautrumas ir 78-82,8% specifiškumas), Nu-DESC (85,7% ir 86,8%) ir CAM (46-100% ir 63-100%) metodus. Intensyviosios terapijos pacientams vertinti tinkami penki iš aprašytų metodų: NEECHAM, ICDSC, CAM, CTD ir DDS. Iš jų dažniausiai naudojamos NEECHAM ir CAM (CAM-ICU modifikacija) bei ICDSC. Senyvo amžiaus pacientams labiausiai tinkamos CAM ir Nu-DESC skalės. Dauguma skalių vertina dėmesingumą, orientaciją, sąmonės pokyčius, kalbėjimo ir judesių tikslingumą. Pakartotinis vertinimas reikalingas Nu-DESC, DOSS ir ICDSC metodams. Dauguma skalių, išskyrus ICDSC ir Nu-DESC, neaptinka hipoaktyvios delyro formos.

Išvados. Lietuvoje stebima delyro hipodiagnostikos problema, kurią spręsti būtų galima pasitelkiant validuotas delyro stebėsenos ir diagnostikos skales. Intensyviojoje terapijoje patikimiausios delyro vertinimo skalės yra CAM-ICU, ICDSC ir DDS. Senyvo amžiaus pacientams patartina taikyti CAM ir Nu-DESC metodus bei IQCODE klausimyną. Hipoaktyvaus delyro vertinimui geriausiai tinka ICDSC bei Nu-DESC metodai. Vis dėlto, esant delyro atrankos ir diagnostikos skalių įvairovei, išlieka poreikis trumpos, greitai ir paprastai pritaikomos, aukšto jautrumo ir specifiškumo suvienodintos vertinimo skalės, tinkamos įvertinti ne tik delyro faktą, bet ir jo subtipą.
ŪMI MEZENTERINIŲ ARTERIJŲ OKLIUZIJA. ETIOLOGIJA, DIAGNOSTIKA, GYDYMAS
Authors: Rimkus Juozas
Published: July 2021

Ūmi mezenterinė išemija (ŪMI) – tai staigiai sumažėjusi ar visiškai nutrūkusi kraujo tėkmė į plonąją žarną ar jos segmentą. Nepaisant tobulėjančios diagnostikos ir gydymo, mirštamumas nuo šios ligos yra labai aukštas. Tyrimo tikslas − aptarti ūmios mezenterinės išemijos etiologiją, diagnostiką ir gydymą.

Literatūros paieška atlikta PubMed, ScienceDirect, Up-ToDate duomenų bazėse. Iš viso atrinkta ir išanalizuota 10 publikacijų, paskelbtų 2013-2020 metų laikotarpiu.

Rezultatai. Ūmi viršutinės mezenterinės arterijos okliuzija gali atsirasti dėl dviejų priežasčių: embolija arba trombozė. Įtariant ŪMI, svarbu išsiaiškinti embolijos ir trombozės riziką didinančius paciento rizikos veiksnius. Pradiniai ŪMI požymiai ir laboratoriniai tyrimai nespecifiški, todėl ligą diagnozuoti sudėtinga. Diagnozės patvirtinimui reikalingi vaizdo tyrimo metodai, iš kurių pirmumas teikiamas kompiuterinei tomografijai su intraveniniu kontrastavimu. ŪMI gydymas pradedamas paciento būklės stabilizavimu: kristaloidų infuzija, nazogastrinio zondo įvedimas, plataus spektro antibiotikai, heparinas. Specifinis gydymas apima atvirus ir endovaskulinius metodus, kurių tikslas − kuo greičiau atkurti normalią žarnyno kraujotaką.
UŽDEGIMINĖ ŽARNŲ LIGA IR PSICHIKOS SUTRIKIMAI
Authors: Rimkus Juozas
Published: July 2021

Krono liga ir opinis kolitas priklauso uždegiminių žarnų ligų grupei. Lėtinė, nenuspėjama ligos eiga ir įprastai jauname amžiuje prasidedantys simptomai blogina gyvenimo kokybę ir didina psichinio distreso riziką, palyginus su bendrąja populiacija. Dažniausios psichikos problemos, kurias patiria sergantieji uždegiminėmis žarnų ligomis, yra depresija ir nerimo sutrikimai. Glaudus ryšys tarp nerimo bei depresijos simptomų ir uždegiminės žarnų ligos aiškinamas naujomis teorijomis apie žarnynosmegenų ryšio disfunkciją. Tyrimo tikslas − aptarti sergantiesiems uždegiminėmis žarnų ligomis pasitaikančius psichikos sutrikimus, jų paplitimą, priežastis ir poveikį ligos eigai. Literatūros paieška atlikta PubMed, Science-Direct, Google Scholar duomenų bazėse. Iš viso atrinkta ir išanalizuota 10 publikacijų, paskelbtų 2013-2020 metų laikotarpiu. Tyrimo rezultatai. Pastaraisiais dešimtmečiais uždegimo reikšmė depresijos atsiradimui buvo intensyviai tyrinėjama. Sergantiesiems depresija buvo nustatytas padidėjęs uždegimą skatinančių citokinų ir ūminės fazės uždegimo baltymų bei sumažėjęs priešuždegiminių citokinų, albumino, transferino, a1-antitripsino kiekis. Panašus mediatorių disbalansas stebimas ir sergant uždegiminėmis žarnų ligomis. Depresija siejama su didesne atkryčių rizika ir prastesniu atsaku į gydymą. Nerimo sutrikimai siejami su didesne operacijų rizika, dažnesniu gydymo režimo nesilaikymu ir suprastėjusia gyvenimo kokybe. Išvados. Psichikos sutrikimai neigiamai veikia uždegiminės žarnų ligos eigą ir baigtį. Asmenų, sergančių uždegimine žarnų liga, psichikos sutrikimų gydymas nėra optimizuotas ir šioje srityje reikia daugiau tyrimų.
Crecimiento e inflación: Alternativas cambiarias para México
Authors: Ortiz Martínez Guillermo , Solís Leopoldo
Published: July 2021

La rápida recuperación de la economía mexicana a partir de la recesión postdevaluatoria de 1976-1977 se ha visto acompañada por una buena dosis de presiones inflacionarias. De continuar estas presiones, el valor de equilibrio del peso, en términos de poder adquisitivo, podría verse amenazado a menos que se lleven a cabo políticas apropiadas. Esta cuestión es particularmente relevante ante las expectativas de ingresos por petróleo en el futuro próximo y, por lo tanto, ante la posibilidad de financiar un tipo de cambio sobrevaluado con todos sus efectos distorsionantes.
Comments on and Corrections to "SVD-Precoded Faster-Than-Nyquist Signaling With Optimal and Truncated Power Allocation"
Authors: Ishihara Takumi , Sugiura Shinya
Published: July 2021

This correspondence corrects the limitations of a system parameter in ``SVD-Precoded Faster-Than-Nyquist Signaling With Optimal and Truncated Power Allocation" in IEEE Transactions on Wireless Communications, vol. 18, no. 12, Dec. 2019. We do not present any novelty in these errata.
5G Evolution for Multicast and Broadcast Services in 3GPP Release 17
Authors: Shrivastava Vinay Kumar , Baek Sangkyu , Baek Youngkyo
Published: July 2021

5G communications system is on the evolution path with present focus on enabling advanced features and new service capabilities. Multicast and Broadcast Services (MBS) are being considered as one of the most promising use cases of 5G. As a late entrant to 3rd Generation Partnership Project (3GPP) 5G standards, MBS work item is presently being developed over existing 5G framework, and is targeted to enhance 5G New Radio and 5G Core Network capabilities for a reliable, low latency, resource efficient, and massive deployment of a wide array of multicast and broadcast services. MBS development entails enhancements for network and user equipment side on architectural, protocol and transmission aspects in order to address a new set of multicast and broadcast service requirements in 5G. In this article, we present an introduction to MBS standardization and outline newly introduced technical features, and their use cases.