bluuebunny/crossref_metadata_2025 huggingface dataset:
Ernest Hart: Editor of the British Medical Journal 1866–1898
Authors: Collins Kenneth
Published: November 2022

Ernest Abraham Hart (26 June 1835–7 January 1898) was the long-time editor of the British Medical Journal. He held strong opinions, and was often controversial but his views generally prevailed. He was born into a Jewish family in London and was educated at the City of London School. He studied medicine at the St George’s Hospital School of Medicine and specialised in diseases of the eye. His medical journalism began with The Lancet in 1857 and in August 1866, he was appointed editor of the British Medical Journal taking it, in his decades of leadership, from a small publication to a significant scientific journal increasing the British Medical Association membership substantially. Julia Frankau's novel of scandal, Dr Phillips: A Maida Vale Idyll (1887) published under the pseudonym of Frank Danby, has a leading character, Dr Phillips, thought to be modelled on Ernest Hart and who murders his wife reviving speculation about the death of Hart's first wife from accidental poisoning.
Mint, sell, repeat: Non-fungible tokens and resale royalties for Indigenous artists
Authors: Harris Elizabeth
Published: November 2022

This article examines whether the Resale Royalty Right for Visual Artists Act 2009 (Cth) provides adequate protections for artists working with non-fungible tokens (NFTs). Focussing on Indigenous Australian artists and the context within which they work, the article assesses whether smart contracts embedded in NFTs provide more secure access to royalties for visual artists, as compared with the Act. The article then considers how the Act can be reformed to provide more comprehensive protections that meet the needs of Indigenous Australian artists working with NFTs.
Policy, professionalism and psychotherapy; the clinical practice guidelines’ dilemma
Authors: Anaf Gil , Prager Shirley
Published: November 2022

Objective

To review a rebuttal to widely published concerns that the Clinical Practice Guidelines (CPG) devalues the role of long-term psychodynamic psychotherapy as a treatment in mood disorders.

Conclusion

There is a wider context to this debate. The CPG presents the RANZCP with a dilemma about treatments, professionalism and policy; it requires amendment.
Berlin is Hotter Than Silicon Valley! How Networking Temperature Shapes Entrepreneurs’ Networking Across Social Contexts
Authors: Scheidgen Katharina , Brattström Anna
Published: November 2022

Our study contributes a contextual perspective on entrepreneurs’ networking, shifting focus from individual-level network structure and networking activities toward understanding networking as a multilevel process involving individual and contextual mechanisms. Through a multiple case study of entrepreneurs in Silicon Valley and Berlin, we introduce networking temperature as novel concept that captures context-bound templates for how entrepreneurs should network, ranging from colder to warmer. As core implications, networking temperature enables a contextualized understanding of tie quality, to explain why networking takes different forms in different contexts, and why entrepreneurs gain more cumulative advantage from their existing relationships in warmer than colder contexts.
Does a Past Category’s Success Influence Existing Entrepreneurial Fundraising?: A Legitimacy Spillover Perspective
Authors: Li Megan Yuan , Dong Charson Cancan , Makino Shige
Published: November 2022

Research on entrepreneurial crowdfunding has focused limited attention to the role of category in investors’ decisions. We examine the legitimacy spillover effect of projects within the same category of industry on the focal project’s fundraising. We decompose category legitimacy into two types—stable versus transient—and investigate their distinct effects on fundraising. Our dataset, derived from 31,767 projects on Kickstarter from 2010 to 2020, confirms the spillover effect of category legitimacy on entrepreneurial fundraising. Furthermore, the spillover effect of stable legitimacy is much stronger than that of transient legitimacy, and this effect weakens when entrepreneurs have greater past successes.
Continuity of Care Advocate Model (CCAM): Healthcare Workers’ Perspectives on Quality Stroke Care at an Acute Unit, Rehabilitation Center and Community Rehabilitation Program in Singapore
Authors: Chiang HL Michelle , Wong Audrey Yoke Poh , Tan Serene Leong Hwee , Mohapatra Litali , Chan Olivia Harmony , Ho Andy Hau Yan
Published: November 2022

Physicians, nurses, social workers, and allied health professionals including physiotherapists and occupational therapists play important roles as they work closely with stroke survivors to improve functional independence in daily activities and quality of life. Yet, in Singapore little is known about their perspectives on what constitute quality stroke care based on their clinical experiences. In this project, our qualitative interviews with 15 healthcare workers at a major stroke center in the country yielded a Continuity of Care Advocate Model (CCAM) to help us better understand our participants’ experience-based perspectives on quality stroke care. We found that CCAM, constructed based on the perspectives of HCWs across a stroke care continuum, is a holistic model of quality stroke care which prioritizes support for patients and their families throughout the patient’s health trajectory. We conclude by discussing how this model is aligned with and differs from current research on definitions of care continuity.
Sibling Dynamics, Marital Satisfaction, and Wellness in Married Turkish Adults
Authors: Aydogan Didem , Ozbay Yaşar , Milevsky Avidan , Kaygas Yasemin
Published: November 2022

Research on sibling dynamics and their outcomes in married adults is limited. The primary objective of this study was to assess how relationships with same and different-sex siblings explain the state of wellness and marital satisfaction in adulthood. Furthermore, the study aimed to evaluate the effects of early childhood sibling relationships on adult well-being and to assess the meditative role of adult sibling relationship characteristics on this effect. A total of 344 married adults participated in the study, 237 of whom (68.9%) were women. The Adult Sibling Relationship-Short Form (ASRQ-SF), Lifespan Sibling Relationship Scale (LSRS), Couple Satisfaction Index (CSI), and Wellness Scale for Emerging Adults (WSEA) indices were used to assess study variables. Results indicated that intimacy between different-sex siblings (brother-sister) predicted marital satisfaction. Furthermore, conflict between same-sex siblings (sister-sister) and intimacy between different-sex siblings (sister-brother, brother-sister) predicted wellness. Additionally, recalled childhood sibling relationship characteristics had significant effects on wellness and that sibling relationship characteristics in adulthood partially mediated this relationship. These results are considered within the framework of sibling relationship development within Turkish culture.
Reciprocal Effects of Career Adaptability and Occupational Self-Efficacy: A Three-Wave Longitudinal Study With Varying Time Lags
Authors: Volmer Judith , Spurk Daniel , Orth Maximilian , Göritz Anja
Published: November 2022

Researchers widely agree upon the pivotal role of career self-management in vocational development. Yet, little is known about how core self-management constructs denoting agentic capacity affect each other reciprocally over time. We address the shortage of existing longitudinal change investigations by proposing and testing a reciprocal model in which career adaptability and occupational self-efficacy as core career self-management constructs are reciprocally interrelated. Cross-lagged panel analyses of three-wave data from a large and heterogeneous sample of employees indicate support for the presence of substantial reciprocal effects of career adaptability and occupational self-efficacy across time lags of three, six, and nine months. From a series of exploratory multigroup analyses, this pattern of results emerges as robust across a range of sociodemographic variables, including gender, age, education, leadership position, and organizational tenure. Moreover, the results remained stable after considering further controls (e.g., future temporal focus, grade point average). Our findings broaden the scope of dynamic vocational research by demonstrating the utility of a change-oriented approach in elucidating the emergence of individuals’ career self-management. We discuss practical implications concerning career intervention strategies, study limitations, and prospects for future research.
Airway and Hemodynamic Considerations for the Anesthetic Management of an Intraluminal Tracheal Plasmacytoma
Authors: Morabito Joseph E. , Simmons Colby G. , Zanotti Giorgio , Mitchell John D. , Bartels Karsten , Wilkey Barbara J.
Published: November 2022

Central airway obstruction due to tracheal tumors presents unique challenges to the anesthesiologist. We present the case of a 44-year-old male taken to the OR for biopsy and resection of an undiagnosed tracheal mass. Intraoperative management was complicated by bleeding and significant hemodynamic instability, necessitating rapid surgical and anesthetic intervention. This ultimately led to abortion of surgical resection. Pathologic examination revealed a primary tracheal plasmacytoma, a rare type of tracheal tumor. Here, we describe anesthetic and hemodynamic considerations for a tracheal plasmacytoma. We discuss the approach to airway management in variable intrathoracic tracheal obstruction and the unpredictability of tracheal tumors.
Instant Karma: How the Karmic-Investment Mindset Affects Customer Engagement With Corporate Charitable Giving Requests
Authors: Xue Joanne (Xunyue) , Mattila Anna S.
Published: November 2022

Corporate charitable giving (CCG) is increasingly pervasive in the global hospitality industry. Among various subtypes of CCGs, many hospitality companies request donations from customers during the service delivery or payment process to encourage customer engagement and co-created social responsibility. Karma—the implicit belief that the universe rewards good deeds and punishes wrongdoings—resonates with consumers’ prosocial behaviors, yet little is known about how karma beliefs, along with various donation elements, affect donation likelihood. Study 1 demonstrates that karma believers are more likely to donate gifts-in-kind than money, as it signals altruism that engenders karmic rewards. Study 2 shows that consumers with weak (vs. strong) karma beliefs are more likely to donate in a public (vs. private) setting due to greater reputational benefits. This research enriches the literature on hospitality CCG marketing and provides insights to managers regarding how to effectively execute donation programs.
Memorial ambiguity: A typology of rhetorical effects in Oklahoma and the wider US context
Authors: Shank Nathan A
Published: November 2022

Memorials and monuments often shape the narratives of public memory surrounding key events and figures, even as they help process and represent the trauma and remembered emotions that those subjects evoke. This essay develops a schema of four types of memorial ambiguity in order to provide more precise analytic tools for understanding memorials. Ambiguous physical representation, ambiguous messages, ambiguous emotions, and ambiguous political responses interrelate as parts of the rhetorical interpretation of memorials. Examples draw from national memorials such as the Iwo Jima Memorial in Washington, DC, and the USS Arizona Memorial in Hawai’i as well as regional examples like Oklahoma’s Yellow Ribbon Memorial commemorating a 1986 postal mass shooting and The Guardian atop Oklahoma’s state capitol. This typology matters to memorial scholars and memorial designers alike: those who seek to theorize memorials ought to have a more developed sense of the rhetorical nature of ambiguity, and those who seek to construct memorials ought to consider the possibly ambiguous effects of their design. Failure to understand memorial ambiguity can lead to forgotten or ineffective memorials.
Minority social influence and moral decision-making in human–AI interaction: The effects of identity and specialization cues
Authors: Wu Yuheng , Kim Ki Joon , Mou Yi
Published: November 2022

In group decision-making, the behavior of each member is sensitive to the social influence of other majority members. Research on majority influence has shown that multiple non-human agents with anthropomorphic cues can exert normative pressure on a lone human decision-maker. However, how individuals perceive and respond to minority influence exerted by a lone machine is rarely discussed. Hence, a between-subjects experiment was conducted to examine how different minority identity (human vs artificial intelligence [AI]) and specialization (specialist vs generalist) cues influence individuals’ perceptions and behavior in response to moral dilemmas in a joint human–AI group. The results confirmed the significant role of specialization cues in predicting in-group identification, source credibility, and conversion behavior. In addition, the participants perceived the human minority as more credible than the AI minority, which prompted conversion behavior when the minority was labeled as a specialist rather than as a generalist.
Exploring the role of Black feminist thought in pre-service early childhood education: On the possibilities of embedded transformative change
Authors: Brady Janelle
Published: November 2022

As a Black feminist scholar who teaches in an early childhood studies program, the author has witnessed how dominant theories and methods used for pre-service early childhood education and care disconnect students from their lived experiences. The detachment of social location in theoretical text, and particularly in developmental discourse, is not isolated to the field; it is instead a result of the fragmentation of knowledge, which is central in the modern colonial project. The author explores what the possibilities are for Black feminist scholarship in pre-service early childhood education and care while unpacking the many racial and intersecting injustices in the field. The dominant research and pedagogy practices in early childhood education and care have limitations, with omissions of the nuances of the critical engagement of students, families and community more broadly through lived experience. When assumptions of detached and ‘objective’ knowledge are centred, then ideas that challenge norms and the status quo are omitted or peripheralized, when they are included. The article explores the possibilities of what the author calls ‘embedded transformative change’ – a change that is central to pedagogy and research in the field of early childhood education and care as opposed to being placed at the margins. Through embedded transformative change, members of pre-service early childhood education and care programs can think of themselves as active agents in change and liberation.
Should health research funding be proportional to the burden of disease?
Authors: Millum Joseph
Published: November 2022

Public funders of health research have been widely criticized on the grounds that their allocations of funding for disease-specific research do not reflect the relative burdens imposed by different diseases. For example, the US National Institutes of Health spends a much greater fraction of its budget on HIV/AIDS research and a much smaller fraction on migraine research than their relative contribution to the US burden of disease would suggest. Implicit in this criticism is a normative claim: Insofar as the scientific opportunities are equal, each patient merits research into their condition proportional to the burden of disease for which that condition is responsible. This claim—the proportional view—is widely accepted but has never been fully specified or defended. In this paper, I explain what is required to specify the view, attempt to do so in the most charitable way, and then critically evaluate its normative underpinnings. I conclude that a severity-weighted proportional view is defensible. I close by drawing out five key lessons of my analysis for health research priority-setting.
Leaf Extract and Active Fractions of Dillenia pentagyna Roxb. Reduce In Vitro Human Cancer Cell Migration Via NF-κB Pathway
Authors: De Debapriya , Chowdhury Priyanka , Panda Sujogya Kumar , Ghosh Utpal
Published: November 2022

Background:

Different parts of Dillenia pentagyna have long been used in traditional medicines to cure several diseases including cancer. However, the mechanism(s) of anti-cancer effects are still unknown. We aimed to elucidate the anti-metastatic potential of ethanolic extracts of leaves of D. pentagyna (EELDP) and active fractions of it in highly metastatic human cancer cells.

Methods:

We screened different HPLC fractions of EELDP based on their anti-metastatic effect. We used TLC and ESI-MS for determining the presence of various phytochemicals in EELDP and fractions. We monitored in vitro anti-metastasis effect of EELDP (0-0.6 mg/ml) and active fractions (0-0.050 mg/ml) on various human cancer cells like A549, HeLa, and U2OS.

Results:

EELDP significantly reduced cell viability and cell migration in A549, HeLa, and U2OS cells. However, higher sensitivity was observed in A549 cells. We screened 2 active HPLC fractions F6 and F8 having anti-MMPs activity. EELDP and active fractions reduced metastasis via the NF-κB pathway, decreased the expression of Vimentin, N-cadherin, and increased the expression of Claudin-1.

Conclusion:

Significant reduction of metastasis by EELDP at a dose of 0.1 mg/ml or by active fractions at 0.050 mg/ml implicates that the active compound(s) present in crude or fractions are extremely potent to control highly metastatic cancer.
Hyperbaric Oxygen Therapy-Induced Molecular and Pathway Changes in a Rat Model of Spinal Cord Injury: A Proteomic Analysis
Authors: Li Zhuo , Hou Xiaomin , Liu Xuehua , Ma Linlin , Tan Jiewen
Published: November 2022

Hyperbaric Oxygen Therapy (HBOT) has definitive therapeutic effects on spinal cord injury (SCI), but its mechanism of action is still unclear. Here, we’ve conducted a systemic proteomic analysis to identify differentially expressed proteins (DEPs) between SCI rats and HBOT + SCI rats. The function clustering analysis showed that the top enriched pathways of DEPs include oxygen transport activity, oxygen binding, and regulation of T cell proliferation. The results of functional and signal pathway analyses indicated that metabolic pathways, thermogenesis, LXR/RXR activation, acute phase response signaling, and the intrinsic prothrombin pathway in the SCI + HBOT group was higher than SCI group.
Applying Critical Grounded Theory to Community Intervention Development Methodology: Designing the Critical Difference Engagement Approach
Authors: Sawyer Jason M , Brady Shane R
Published: November 2022

Multiple factors contribute to community practice’s ongoing challenge of developing effective, evidence-informed, and socially just practice interventions. Currently, rationally driven systematic reviews dominate intervention design and development in various interprofessional applied health and human service fields, including community practice. As a result, community interventions often undergo significant development outside complex community contexts in which social problems manifest. Drawing from a case example of one author’s participation in a community engaged intervention development study based on mobilizing across differences, this piece advances an inclusive approach to community-based participatory intervention development driven by critical grounded theory. Undergirded by critical research perspectives, the article offers an early-stage intervention development methodology derived from the field in collaboration with community practitioners and resident leaders. Built upon existing interdisciplinary scholarship, it blends prominent intervention development frameworks, participatory research approaches, and critical grounded theory methods. Authors aim to aid scholars, practitioners, and community leaders in developing socially just, inclusive, and contextually relevant intervention approaches that originate from within communities directly impacted by social problems.
Analysis of turning chip morphology with various tool geometries using finite element modeling and simulation to optimize product sustainability
Authors: Wakjira Melesse Workneh , Janaki Ramulu Perumalla
Published: November 2022

This paper focuses on finite element (FE) modeling using a Lagrangian approach with the ABAQUS/Explicit code to simulate the morphology of CSN 12050 carbon steel chips obtained using different tool rake and flank angles. The cutting operation was performed with a 3D model setup based on the cutting tool to determine the impact of the tool rake and flank angles on the total energy ( ETOTAL), the von Mises stresses, and the cutting force. In these simulations, using adaptive meshing for the tool, 0°, 5° and 10° rake angles, 0° and 6° flank angles, and 0.2-mm and 0.5-mm cut depths were considered as process parameters and the continuous chip morphology was predicted. The tool with 10° rake and 6° flank angles projected moderate machined surface integrity. The FE analysis tool predicted increased von Mises stresses and reduced cutting forces with the 10° rake and 6° flank angles. The maximum ETOTAL and cutting force were obtained for both cut depths when using a tool with 0° and 5° angles. Additionally, experimental results for the mechanical morphology properties of untreated, annealed and recrystallized CSN 12050 carbon steel chips showed that the predicted and experimental chip morphologies agreed well.
Impact of the COVID-19 pandemic on cardiovascular heart disease medication use: time-series analysis of England’s prescription data during the COVID-19 pandemic (January 2019 to October 2020)
Authors: Barrett Ravina , Hodgkinson James
Published: November 2022

Background:

Management of high blood pressure (BP) typically requires adherence to medication regimes. However, it is known that the COVID-19 pandemic both interrupted access to some routine prescriptions and changed some patient health behaviours.

Aim:

This study, therefore, retrospectively investigated prescription reimbursement of cardiovascular (CVD) medicines as a proxy measure for patient adherence and access to medicines during the pandemic.

Methods:

A cohort study of all primary care patients in England prescribed CVD medicines. The exposure was to the global pandemic. Prescriptions were compared before and after the pandemic’s onset. Statistical variation was the outcome of interest.

Results:

Descriptive statistics show changes to monthly prescriptions, with wide confidence intervals indicating varying underlying practice. Analysis of variance reveals statistically significant differences for bendroflumethiazide, potassium-sparing diuretics, nicorandil, ezetimibe, ivabradine, ranolazine, colesevelam and midodrine. After the pandemic began (March–October 2020), negative parameters are observed for ACE inhibitors, beta-blockers, calcium channel blockers, statins, antiplatelet, antithrombotics, ARBs, loop diuretics, doxazosin, bendroflumethiazide, nitrates and indapamide, indicating decelerating monthly prescription items (statistically significant declines of calcium channel blockers, antithrombotic, adrenoreceptor blockers and diuretics) of CVD medicines within the general population. Many data points are not statistically significant, but fluctuations remain clinically important for the large population of patients taking these medications.

Conclusion:

A concerning decline in uptake of CVD therapies for chronic heart disease was observed. Accessible screening and treatment alongside financial relief on prescription levies are needed. A video abstract is (4 min 51 s) available: https://bit.ly/39gvEHi
Aerodynamic comparisons between Al Rihla and recent World Cup soccer balls
Authors: Goff John Eric , Hong Sungchan , Asai Takeshi
Published: November 2022

Wind-tunnel experiments were performed on Al Rihla, Telstar 18, Brazuca, and Jabulani, official match soccer balls used in the World Cup in 2022, 2018, 2014, and 2010, respectively. Aerodynamic coefficients extracted from wind-tunnel results were used to create computer simulations of trajectories of kicked soccer balls. The newest World Cup ball, Al Rihla, could be kicked for longer range compared to its recent predecessors. But there is also the possibility that knuckling effects at large speeds could be seen in the flights of the new ball kicked with little to no spin. Measurements were made of each soccer ball’s total seam length and seam width and depth. Two different measurement techniques were employed to assist with accuracy. Wider and deeper seams led to smaller critical speeds.
Incremental theory of personality attenuates the effect of environmental uncertainty on intertemporal choices
Authors: Geng Xiaowei , Li Mengyue , Zhang Feng , Li Wenjing , Liu Dan
Published: November 2022

To examine the impact of environmental uncertainty on individuals’ intertemporal choices and the moderating effect of implicit personality theory, two studies were conducted. Study 1 investigated the moderating role of implicit personality theory in the influence of environmental uncertainty on intertemporal choice using questionnaires. Study 2 examined whether priming incremental personality theory could change entity theorists’ intertemporal preference in an uncertain environment. The results showed that implicit personality theory plays a moderating role in the influence of environmental uncertainty on intertemporal choice. For entity theorists, the delay discounting rate was positively correlated with environmental uncertainty. In contrast, for incremental theorists, the delay discounting rate was not significantly correlated with environmental uncertainty. After priming incremental personality theory, entity theorists’ delay discounting decreased significantly. Thus, we conclude that incremental personality theory buffers the effect of environmental uncertainty on intertemporal choice.
Hip morphology on initial ultrasound predicts hip morphology at one year in developmental dysplasia of the hip
Authors: Kanakamedala Ajay C , Jejurikar Neha S , Castañeda Pablo
Published: November 2022

Purpose:

This study aimed to determine whether point-of-care ultrasound performed during the Pavlik method treatment of developmental dysplasia of the hip predicts acetabular morphology at 12 months of age.

Methods:

We reviewed the medical records, ultrasounds, and radiographs of patients treated successfully with the Pavlik method between 2017 and 2019. We performed sonographic measurements on point-of-care ultrasound at the initial presentation, the Pavlik discontinuation, and an additional sonographic follow-up. We measured the acetabular index on a plain anteroposterior radiograph of the pelvis obtained at a minimum of 12 months of age. Spearman’s rank correlation coefficient was used to analyze for correlation between sonographic measurements and the acetabular index.

Results:

A total of 72 patients were included in the final analysis. There were no residual or late dysplasia cases at the last radiographic follow-up (mean age = 14.8 ± 2.7 months). Sonographic parameters at the initial presentation significantly correlated with the acetabular index at the final radiographic follow-up (p < 0.001). Patients with worsening degrees of developmental dysplasia of the hip based on stability on sonographic testing (stable, unstable, or dislocated) had higher acetabular indices at the final radiographic follow-up (p < 0.05).

Conclusion:

Point-of-care ultrasound at initial presentation and the Pavlik discontinuation significantly correlate with acetabular morphology at 1–1.5 years of age. At initial presentation, hips that were unstable or dislocated on point-of-care ultrasound had significantly greater acetabular indices than stable hips at the final follow-up.

Level of evidence:

level IV case series.
The Chinese Communist Party as a Global Force
Authors: Pieke Frank N.
Published: November 2022

The Chinese Communist Party (CCP) is currently in the throes of redefining itself as not just China's ruling party, but also as the dominant political force of global China. Following the path of Chinese globalisation, this project overlaps with – but is different from – China's much maligned strategy of influencing and interfering in the society and politics of other countries. The principal aim of the CCP's global extension is not to meddle in the affairs of other countries, but tying Chinese people, goods, money, business, and institutions that have ventured abroad back into the strategy and domestic system of China and the CCP. The article shows that China's emerging superpower is informed both by China's unique pattern of globalisation and the CCP's own understanding of the nature, aims, and modalities of its rule, which can only partially be compared to those of earlier superpowers.
The hard truth about soft skills: Exploring the association between leadership competency and career advancement of allied health professionals
Authors: Koh Jeremy Meng-Yeow , Ang Hui-Gek , Lee Jeffrey , Pua Yong-Hao
Published: November 2022

Backgroud:

Globally, employee engagement in healthcare organisations is low, with career advancement one of its main determinants. It may be useful for healthcare organisations to determine the factors of career advancement, to guide them to more effectively engage their workforce. Leadership competency is factor that may be crucial in influencing career advancement for healthcare employees. To our knowledge, a comprehensive analysis on its impact on the perception of career advancement within the healthcare setting has not been conducted.

Research Design:

An ecological, cross-sectional study was conducted, aimed at examining the association between leadership competency of healthcare professionals and perceptions of career advancement. Poisson generalized-estimating-equation models were fitted to estimate the adjusted rate ratios with bootstrap 95% confidence intervals for the associations of the AHEAD items with the number of favourable responses on the career advancement items. In each model, we accounted for clustering by departments and controlled for length of service as a confounder.

Results:

Statistically significant predictors of perception of career advancement were found, and included skills - Interpersonal Skills (aRR 1.53 CI 1.12–2.96), Motivating (aRR 1.31 CI 1.10–2.16), and Mentoring (aRR 1.30 CI 1.08–1.13); and values - Compassion (aRR 1.37 CI 1.17–3.40), and Collegiality (aRR 1.31 CI 1.00–1.99).

Conclusion:

Our findings show an association between some components of leadership competency and the perception of career advancement. These results provide initial evidence that apart from hard skills, soft skills may play an equally (or more important) role in influencing the perception of career advancement.
The 50 most impactful articles on the medial ulnar collateral ligament: An altmetric analysis of online media
Authors: Kirloskar Kunal M , Civilette Matthew D , Rate William R , Cohen Andrew S , Haislup Brett D , Nayar Suresh K , Bodendorfer Blake M , Gould Heath P
Published: November 2022

The purpose of this study was to use the Altmetric Attention Score to determine the 50 most impactful medial ulnar collateral ligament articles in online media and compare their characteristics to the most-cited medial ulnar collateral ligament articles in the scientific literature. The Altmetric database was queried to identify all published articles about the medial ulnar collateral ligament, and this list was stratified by the Altmetric Attention Score to identify the 50 highest scoring articles. Several data elements were extracted, including article topic, article type, journal name, and the number of online mentions on Facebook, Twitter, news, and other platforms. Each article’s geographic origin was determined based on the institutional affiliation of the first author. Our index search yielded 1283 articles published between 1987 and 2020, from which the 50 articles with the highest Altmetric Attention Scores were included for analysis. Altmetric Attention Scores of the top 50 medial ulnar collateral ligament articles ranged from 20 to 482 (median: 32, interquartile range: 20–62). The most common article type was original research (72%), and the most common topic was epidemiology/risk factors (26%). A majority of studies were Level 3 (36%) or Level 4 evidence (36%). Of the top 50 medial ulnar collateral ligament articles, 94% originated from the United States. A few articles had a high Altmetric Attention Score, suggesting that medial ulnar collateral ligament research does not generate consistently high online attention. The lack of Level 1 studies suggests the need for high-level studies on the medial ulnar collateral ligament. Most studies originated in the United States and were published in the American Orthopaedic Society for Sports Medicine–affiliated journals. The medial ulnar collateral ligament articles included in this study differed substantially from a previous report of the most-cited medial ulnar collateral ligament articles in the literature, suggesting that alternative metrics add a unique dimension to understanding the overall impact of published research on the medial ulnar collateral ligament.
Pedicled dorsal penile skin tube as neourethra in total penectomy for primary male urethral carcinoma
Authors: Yepes Christian , Bandini Marco , Joshi Pankaj M , Alrefaey Ahmed A , Bhadranavar Shreyas , Bafna Sandeep , Kulkarni Sanjay B
Published: November 2022

Background:

The aim of this article is to present our experience of pedicled dorsal penile skin tube as neourethra after radical penectomy due to invasive primary male carcinoma of anterior urethra.

Methods:

This is an observational descriptive study including seven men with primary urethral carcinoma who underwent radical penectomy between 2018 and 2021. Instead of urinary derivation with suprapubic catheter, perineal urethrostomy, or bladder orthotopic/heterotopic reconstruction, patients underwent reconstruction of the anterior urethra with a pedicled dorsal penile skin tube. In brief, before corpora amputation and radical urethrectomy, the dorsal penile skin is preserved to reconstruct the neourethra. The distal end of the skin is anastomosed with the proximal urethral stump (usually membranous urethra) to assure continuity of the urinary tract, without jeopardising urinary continence. Finally, the flap is tubularized with two layers of watertight running sutures.

Results:

Median age was 50 (35–70) years. Histology revealed squamous cell carcinoma in all patients. Almost 100% of patients presented locally advanced (pT3–4, G3) disease and received perioperative chemotherapy (MVAC). The median follow-up was 10 (5–24) months. Median operative time was 230 min (190–315). There were not severe (Clavien–Dindo III–IV) perioperative complications. All patients were able to void in standing position through the reconstructed neourethra. No patients reported post-operative incontinence. Two patients died after 8 and 11 months from surgery.

Conclusion:

This new technique of using the dartos-based dorsal penile skin tube urethroplasty offers the possibility to void in standing position after radical penectomy with no need of urinary derivations.

Level of evidence:

Not applicable.
Studying the influence of e-personalisation on the online experience of consumers with disabilities: Ease of use as a source of pleasure
Authors: Dampérat Maud , Jongmans Eline , Jeannot Florence , Giuffrida Tanguy
Published: November 2022

This research studies the online consumer experience and, more specifically, the role of design e-personalisation of e-commerce websites adapted to the needs of consumers with disabilities (perceptual, cognitive or physical). It examines the roles of ease of use and pleasure of use as explanatory mechanisms for the effects of design e-personalisation on e-commerce website reuse and positive word-of-mouth intentions. We propose an online consumer experience model based on perceived design e-personalisation and test it empirically with structural equations on a sample of 117 participants from a panel of French Internet users who are more than 55 years old and have disabilities. The results highlight a serial double mediation of design e-personalisation on reuse and word-of-mouth intentions via ease of use and pleasure of use.
Juvenile hyperinsulinism in a Maine Coon kitten
Authors: Kornya Matthew , Abrams-Ogg Anthony , Comeau Dominique , Caswell Jeff
Published: November 2022

Case summary

A 5.5 month-old intact male Maine Coon cat was presented to a referral hospital for a history of muscle fasciculations, lethargy and seizures associated with refractory hypoglycemia. Diagnostic testing for hypothyroidism, hyposomatotropism or hypoadrenocorticism, inborn errors of metabolism (ie, storage diseases and urea cycle disorders), infection or iatrogenic hypoglycemia were negative. An inappropriately high serum insulin level was noted in the face of marked hypoglycemia. The insulin:glucose ratio was 0.44 (<0.3) and the amended insulin:glucose ratio was 1268 (<30). Thoracic radiography and abdominal ultrasonography did not identify a cause for this elevated insulin level. Stabilization with a low, but adequate, blood glucose occurred with corticosteroid therapy, with further significant improvement with the addition of diazoxide. Peripheral neuropathy developed several months later, and concerns for quality of life led to humane euthanasia approximately 1 year after the initial diagnosis. Insulin levels remained high at the time of euthanasia. Necropsy found no gross lesions, though microscopic degeneration of the sciatic nerve and subjectively mildly increased size and number of pancreatic islets was noted. These findings were consistent with a diagnosis of congenital hyperinsulinism.

Relevance and novel information

This is the first reported case of congenital hyperinsulinism in a cat and may parallel the diffuse form of hypoglycemic hyperinsulinism reported in humans and a single dog. It should be considered a differential diagnosis in kittens presenting for refractory hypoglycemia.
Profiles of resilience in multiple sclerosis family care-partners: A Canadian cross-sectional study
Authors: Cardwell Katherine , McKenna Odessa , Steffener Jason , Pilutti Lara , Fakolade Afolasade
Published: November 2022

Background

Psychological resilience may play an important role in protecting multiple sclerosis care-partners from the negative effects of their support role. However, predictors of resilience in this population have yet to be identified.

Objectives

To identify characteristics predictive of psychological resilience in multiple sclerosis care-partners as informed by the Ecological Model of Resilience.

Methods

Informal multiple sclerosis care-partners ( n = 540) completed an online survey. Psychological resilience was measured using the 25-item Connor-Davidson Resilience Scale. Sociodemographic and care-context predictors of resilience were analyzed using hierarchical regression.

Results

The mean resilience score was 59.0 ( SD = 7.6) out of a possible 100. Sociodemographic variables accounted for 31% of the variance in resilience scores in multiple sclerosis care-partners. When care-context variables were incorporated into the model, 55% of variance was explained ( F[7,320] = 26.824, p < 0.001). Each group of variables remained significant in both low disability and high disability models. Social support was the only individual variable that remained significant across all models ( p < 0.05).

Conclusions

Multiple sclerosis care-partners differ strikingly from other caregiving populations. Both sociodemographic and care-context variables were found to promote or hinder resilience in multiple sclerosis care-partners. Social support, in particular, may be an important target for promoting resilience in multiple sclerosis care-partners and could be leveraged in future initiatives.
“It’s All About the Look”: Making Sense of Appearance, Attractiveness, and Authenticity Online
Authors: Foster Jordan
Published: November 2022

Existing research on Instagram suggests that the mobile application is dominated by a cast of hegemonically attractive influencers. But calls for greater diversity and inclusion are on the rise, raising important questions about how social media influencers and the industry personnel who support them understand diversity and negotiate appearance ideals. Drawing on 40 interviews with influencers and industry personnel as well as a year of online observation, I find that hegemonic ideals surrounding appearance and attractiveness continue to shape who is (and isn’t) perceived as worthy of visibility online. Industry personnel and influencers alike share that these ideals play an important role in cultivating a following on social media but remain convinced that change is underway. Emphasizing the importance of influencers’ relatability and perceived authenticity, influencers, agents, and brand representatives shift focus away from broader issues surrounding the platform including the role that industry personnel play in moderating and constraining opportunities for diversity online.
Job Satisfaction as a Predictor of Wellbeing Among Secondary School Teachers
Authors: Hussain Sadiq , Saba Noor us , Ali Zaigham , Hussain Hina , Hussain Ammar , Khan Asadullah
Published: November 2022

This research was conducted to study the association between job satisfaction and the wellbeing of secondary school teachers from Gilgit, Pakistan. A total of 167 teachers (89 males and 78 females) from both private and public schools were recruited for this study. A job satisfaction survey by Spector was administered to participants along with World Health Organization (WHO) wellbeing index. Results showed that teachers’ job satisfaction (pay, promotion, fringe benefits, contingent rewards, operating conditions, coworkers, nature of work, and communication) was significantly and positively related to their wellbeing. Teachers from public schools have higher job satisfaction and wellbeing as compared to teachers from private schools. Stepwise regression analysis indicated that after controlling the job sector their level of job satisfaction in terms of communication independently predicted their wellbeing.
High-Demand Spinal Deformity With Multi-Rod Constructs and Porous Fusion/Fixation Implants: A Finite Element Study
Authors: Panico Matteo , Chande Ruchi D. , Lindsey Derek P. , Maria Tobia Villa Tomaso , Yerby Scott A. , Brayda-Bruno Marco , Bassani Tito , Polly David W. , Galbusera Fabio
Published: November 2022

Study Design

Basic science (finite element analysis).

Objectives

Pedicle subtraction osteotomy (PSO) at L5 is an effective treatment for sagittal imbalance, especially in select cases of patients showing kyphosis with the apex at L4-L5 but has been scarcely investigated. The aim of this study was to simulate various “high-demand” instrumentation approaches, including varying numbers of rods and sacropelvic implants, for the stabilization of a PSO at L5.

Methods

A finite element model of T10-pelvis was modified to simulate posterior fixation with pedicle screws and rods from T10 to S1, alone or in combination with an L5 PSO. Five additional configurations were then created by employing rods and novel porous fusion/fixation implants across the sacroiliac joints, in varying numbers. All models were loaded using pure moments of 7.5 Nm in flexion-extension, lateral bending, and axial rotation.

Results

The osteotomy resulted in a general increase in motion and stresses in posterior rods and S1 pedicle screws. When the number of rods was varied, three- and four-rod configurations were effective in limiting the maximal rod stresses; values approached those of posterior fixation with no osteotomy. Maximum stresses in the accessory rods were similar to or less than those observed in the primary rods. Multiple sacropelvic implants were effective in reducing range of motion, particularly of the SIJ.

Conclusions

Multi-rod constructs and sacropelvic fixation generally reduced maximal implant stresses and motion in comparison with standard posterior fixation, suggesting a reduced risk of rod breakage and increased joint stability, respectively, when a high-demand construct is utilized for the correction of sagittal imbalance.
Intra-articular Injection of Mesenchymal Stem Cells After High Tibial Osteotomy: A Systematic Review and Meta-analysis
Authors: Jin Lingpeng , Yang Guang , Men Xiaoqian , Zhang Jian , Chen Zhen , Li Zhongwei , Li Yusheng , Ma Jun , Dong Jiangtao
Published: November 2022

Background:

Multiple studies have investigated the use of mesenchymal stem cells (MSCs) for patients undergoing high tibial osteotomy (HTO), and the effectiveness thereof remains controversial.

Purpose:

To analyze the effectiveness of intra-articular MSC injection in patients who underwent HTO in terms of clinical outcomes, radiological outcomes, and cartilage repair by a meta-analysis of the available literature.

Study Design:

Systematic review; Level of evidence, 3.

Methods:

The electronic databases of PubMed, Embase, Web of Science, and the Cochrane Library were searched from their inception to October 30, 2021, for comparative studies between patients who underwent HTO with and without intra-articular injection of MSCs, according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Study quality was assessed by the Coleman Methodology Score (CMS). Data with comparable results were pooled for meta-analysis. The primary outcomes of interest were the Hospital for Special Surgery (HSS), International Knee Documentation Committee (IKDC), Knee injury and Osteoarthritis Outcome Score (KOOS), and Lysholm scores, as well as the International Cartilage Regeneration & Joint Preservation Society (ICRS) grade of cartilage repair. Radiological outcomes including femorotibial angle, posterior tibial slope, and hip-knee-ankle (HKA) angle were included as secondary outcomes. A fixed-model effect was used for meta-analyses with low heterogeneity between studies ( I 2 < 25%), while the random-model effect was used for medium- to high-heterogeneity analyses ( I 2 ≥ 25%).

Results:

A total of 843 studies were screened, of which 6 studies with 452 patients met the inclusion criteria and were included. The mean CMS was 81.17. Patients with MSC injection had significantly higher Lysholm scores ( P = .007) and HSS scores ( P = .01) and higher proportions of ICRS grade 1 ( P = .03) and grade 2 ( P = .02) cartilage repair in the medial femoral condyle and grade 2 cartilage repair in the tibial plateau ( P = .04). There were no significant differences between groups in the IKDC score, KOOS Pain and Symptoms subscales, femorotibial angle, posterior tibial slope, or HKA angle.

Conclusion:

Intra-articular MSC injection may enhance the cartilage repair for patients who undergo HTO. However, evidence of improvement in knee functions remains limited.

Registration:

CRD42021291345 (PROSPERO).