bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of a nonrandomized workplace health promotion program in a Spanish multinational company and its effects on cardiovascular risk factors and weight-related outcomes
Authors: Laura Gómez-Paredes , María José Aguado-Benedi , Luis Reinoso-Barbero
Published: October 2022

Objectives: The aim of this study was to evaluate the effects of a global health promotion intervention in the workplace on cardiovascular risk factors and weight-related outcomes in offices workers after two years. Methods: This nonrandomized retrospective observational study analyzed data of two medical check-up of 728 office workers, over 40 years old: intervention group (376) and control (352) at baseline and after 2 years of a global health promotion program (based on nutrition, physical activity, and mental health) of mixed approach (individual, group and organizational) in the workplace of the intervention group. Results: Systolic and diastolic blood pressure experienced a statistically significant decrease (p ˂ 0.05) at 2 years of -0.94 mm Hg and -0.79 mm Hg in the intervention group versus the control group whose changes were + 0.02 mm Hg and -0.38 mm Hg. Glucose also decreased 1.59 mg/dl more in the intervention group. Lipids, smoking, body mass index or waist circumference did not undergo relevant modifications. Conclusion: This program improved blood pressure and glucose of office workers after two year follow-up, even among employees with low cardiovascular risk. However, according to the findings, this intervention was not as effective as expected in improving weight-related outcomes and cardiovascular risk in an office worker population. Companies should strengthen, not only an overall health intervention, but also individual and personalized advice in the fight against cardiovascular risk.
Pastoral care for children in conflict with the law at correctional facilities
Authors: TLALE Lloyd Daniel
Published: October 2022

The purpose of this paper is to examine pastoral care standards afforded to children in conflict with the law (CCL) at correctional facilities. Pastoral care is the response by caregivers to the needs of young offenders such as emotional suffering and moral injury. Pastoral care plays an essential role in the lives of the CCL. The need for pastoral care and assistance for CCL with several personal problems is growing. This study employs interpretive qualitative paradigm to investigate the experiences of the young offenders and the role played by pastoral care in correctional facilities, the content of pastoral care and the degree to which pastoral care is beneficial to rehabilitation. The study, which took place in 2020, included eighteen participants. The findings reveal that pastoral care utilise a combination of religious and lay methods of counselling and is highly favourable to rehabilitation. Further, it was found that the people offering pastoral care view rehabilitation of CCL as fundamental to correctional treatment and has been linked to the decline in reoffending. The article concludes that the serious shortage of trained individuals to offer beneficial pastoral care and counselling for (CCL).
DIGITAL TRANSFORMATION STRATEGY: DIGITAL COMPETENCIES OF A RAILWAY ENGINEER
Authors: Rimskaya O. N. , Parkhaev A. A. , Chomova N. A.
Published: October 2022

Scientific and technological progress amid the process of global digitalisation has prompted the demand for professions in relevant fields such as logistics, analytics, agriculture, industrial manufacturing, transport, and primarily for engineering and technical workers. Russian railways require not only physical infrastructure, but also digital skills of its operation by engineering and technical workers in order to integrate into the digital economy. The aim of the article is to study modern requirements for the professional competencies of railway engineers, primarily their digital literacy and the ability to work with special software. The authors mention the need for an engineer to have softskills and hardskills. The article provides a list of the main software complexes that are included in the special digital competencies of a railway engineer.

The authors of the article through the example of railway transport, describe the directions of digitalisation of railway transport, which is a link between the branches of the national and partly global economy. The emphasise the advanced development of scientific and technological progress in the transport industry – the “Digital Railway” project, which generates related tasks, one of which is the modern training of engineering personnel and the consolidation of digital competencies and metaskills in professional standards.
STRATEGY OF DIGITAL TRANSFORMATION OF INDUSTRIAL ENTERPRISES: THE EFFECTS OF THE INTRODUCTION OF SMART MANUFACTURING TECHNOLOGIES
Authors: Ilkevich S. V.
Published: October 2022

The socio-economic effects from the introduction of smart manufacturing technologies are of significant interest in terms of their generalisation and systematisation at the current stage of the digital transformation on industrial enterprises, as well as the objectives in the context of industrial modernization and new business model development. The proposed systematisation is based on the allocation of three groups of socio-economic effects according to the main direction of their action. The first group of effects primarily leads to reduction in the costs of industrial enterprises. The second group of effects leads mainly to an increase in revenues: some effects to a greater extent in the short and medium term, others in the long term, including through the creation of long-term distinctive capabilities, unique competencies, and sustainable competitive advantages for industrial companies. The third group of effects includes social and economic effects that are broader in focus and have a multiplicative effect, as well as the character of positive externalities (external effects).

As a result of systematisation, the author identified in three groups, respectively, 12, 8 and 13 effects from the implementation of the complex of smart manufacturing technologies. The author stresses the particular importance of studying the socio-economic effects from the implementation of smart manufacturing technologies, since many improvements at the intersection of production and social transformation are currently insufficiently studied. It contrasts to the core production effects, many of which have been studied in sufficient detail by the scientific and expert communities. Systematisation, classification, differentiation and quantitative assessment of various socio-economic effects of the complex of smart manufacturing technologies can and even in a certain sense should (in the context of the tasks to modernise the economy and industries of the Russian Federation) become a separate subject area at the intersection of performance management and smart production.
Factor Structure of the Russian Version of the Somatic Symptom Scale-8 (SSS-8)
Authors: Zolotareva A.A.
Published: October 2022

The Somatic Symptom Scale-8 (SSS-8) is one of the most common and psychometrically sound instruments for self-reporting somatization and eight specific somatic symptoms [7]. Objective. This study was aimed to adapt and examine the factor structure of the Russian SSS-8. Methods. A total sample of 167 care home residents completed the Russian version of the SSS-8 and questionnaire covering socio-demographic information. Results. Exploratory and confirmatory factor analyses showed that the adapted scale demonstrated a single-factor structure evaluating the somatization total score via medically unexplained symptoms (stomach or bowel problems; back pain; pain in arms, legs, or joints; headaches; chest pain or shortness of breath; dizziness; feeling tired or having low energy; trouble sleeping). The Cronbach’s α coefficient for the SSS-8 total score was 0,76, indicating the good internal consistency. Conclusions. The Russian version of the SSS-8 is a reliable and valid measure assessing somatic symptoms in care home residents.
Predictive Models for ABS and TPMS based on Gaussian Naïve Bays
Authors: Vanjire Sachin , Patil Sanjay
Published: October 2022

The car industry is currently preoccupied with the issue of safety. The increasing number of accidents occurring around the world as a result of automobile problems is a major contributing factor to these incidents. The amount of complicated electronics that is used in vehicles is becoming more prevalent every day. A great effort has been made in evaluating vehicle features in relation to vehicle components. Through such systems, a smart architecture and complex function designs are involved. During all of this vehicle transformation and evolution, the automotive industry recognises a high demand for vehicle safety. While designing and manufacturing this system, automotive experts understand a need for a strict monitoring and feedback system for complex vehicle architecture, which can notify the end user if there is any indication of a failure ahead of time.

In order to effectively participate in vehicle design activities, it is critical to grasp the significance of safety features. Tire system failures and braking system failures have played a large role in several recent traffic accidents. The failures of the tyre system and the braking system in the vehicle are addressed in this study. While investigating this system, it is discovered that it is supported by complex electrical systems, which include an ECU (electronic controller unit), sensors, and a wire system.

Through the use of these technologies, censored data can be processed in a timely manner and made available for diagnostic purposes. Nevertheless, car diagnostics is needed after any vehicle failure but that does not serve the aim of maintaining vehicle safety. As a result, predictive analysis or predictive diagnostics may be a viable option for informing the driver about the health of a particular vehicle component in advance. In this study, the author discusses the concepts of vehicle prognostics for the tyre pressure monitor system and the antilock braking system, which are accomplished using a statistical method of machine learning. In today's world, machine learning is expanding in breadth, and the world is becoming more aware of its enormous potential in the field of data analytics. It is the purpose of this study to introduce methodologies by which machine learning can assist vehicle predictive analytics to attain the intended goal of vehicle safety.The author of this article discusses how Bayesian statistics may be used to produce predictions in the form of probability estimation. The prediction's outcome is thoroughly analysed.
Medio natural interdisciplinar: taller didáctico para estudiantes del Grado de Educación Primaria
Authors: Robles Moral Francisco Javier , Martínez Hernández Carlos , Cifo Izquierdo María Isabel , Farinós Celdrán Pablo
Published: October 2022

En el sistema educativo actual se concede mucha importancia al trabajo interdisciplinar y al aprendizaje significativo, cercano al entorno físico y social del alumnado. En este contexto y con el objetivo de demostrar la hipótesis de que el medio natural puede ser un espacio eficaz para canalizar proyectos educativos interdisciplinares, se diseñó un taller didáctico en un espacio natural dirigido a docentes en formación, con una serie de actividades prácticas para adquirir destrezas, valores y conocimientos de tres áreas: Educación Física, Ciencias de la Naturaleza y Ciencias Sociales. En el taller participaron 29 estudiantes de tercer curso del Grado en Educación Primaria de ISEN Centro Universitario. Para la puesta en práctica se aplicó un procedimiento evaluativo, que estuvo conformado por un cuestionario post-actividad y una adaptación de la técnica del tendero de los deseos, que fueron analizados estadísticamente. Los participantes demostraron una notable adquisición de conocimientos en las tres áreas, aunque claramente mayor en Ciencias Sociales, y mostraron con éxito una adecuada transferencia didáctica interdisciplinar. Finalmente, se pone de manifiesto la necesidad de que los futuros docentes conozcan y sepan aprovechar didácticamente los recursos que ofrece el medio natural desde una perspectiva constructivista, en aras de una mejor formación integral.
Evaluación del proceso de digitalización de un centro de enseñanza secundaria con la herramienta SELFIE
Authors: Fernández Miravete Ángel David , Prendes Espinosa Mª Paz
Published: October 2022

El Marco Europeo para Organizaciones Educativas Digitalmente Competentes (DigCompOrg) se convierte en el modelo que permite a los centros educativos emprender un proceso de digitalización de forma sistémica. Este trabajo evalúa dicho proceso en un centro de Educación Secundaria Obligatoria de la Región de Murcia durante los cursos 2018-2019 y 2020-2021 con una muestra total de 526 participantes el primer año y 461 participantes el segundo (entre alumnado, profesorado y directivos). Se presenta una investigación evaluativa apoyada en un método mixto y un diseño de caso único en la que se aplican técnicas cuantitativas (cuestionario SELFIE) y cualitativas (grupo de discusión). El análisis de la información se ha centrado en las áreas temáticas relacionadas específicamente con la noción de organización educativa que contempla el modelo europeo: liderazgo, infraestructura y equipos, prácticas de evaluación y colaboración y redes. Los resultados permiten al centro educativo hacer un autodiagnóstico de su capacidad digital, así como establecer acciones para mejorar su proceso de digitalización. Una de las principales conclusiones del estudio es que dichas áreas, pese a ser relegadas con frecuencia, son fundamentales para toda organización educativa que aspire a ser digitalmente competente.
Revisión bibliográfica sobre el uso de metodologías activas en la Formación Profesional
Authors: Fernández Olivero Eva Denise , Simón Medina Natalia María
Published: October 2022

Diseñar experiencias educativas, a través de metodologías activas, comprende una serie de recursos docentes, que permiten una actividad formativa adaptada a los intereses y capacidades del alumnado, también del alumnado de Formación Profesional (FP). En este sentido, el objetivo del trabajo es analizar el uso de estas metodologías activas en concreto en el módulo de Formación y Orientación Laboral (FOL) de los Ciclos Formativos de Grado Medio y Superior. El método utilizado ha sido una revisión bibliográfica de 30 artículos publicados en acceso abierto de 2012 a 2020, en diferentes bases de datos, identificándose para ello unos criterios de inclusión (artículos referidos al marco de la FP en España, de libre acceso y publicados en revistas científicas) y exclusión (trabajos de campo fuera de España, TFM y TFG). El análisis ha versado en la identificación del tipo de metodología empleada en el estudio, la muestra, los objetivos planteados, y los resultados obtenidos. El estudio revela que el uso de las metodologías activas en el marco de la FP mejora las necesidades actuales de mercado laboral, siendo las metodologías basadas en el uso de las TIC y el Aprendizaje Basado en Juegos y Gamificación las más empleadas por el profesorado.
Presentación
Authors: Ribera Puchades Juan Miguel , Garrido Martos Rocío
Published: October 2022

MONOGRÁFICO“Experiencias y herramientas para la innovación docente”PRESENTACIÓN
ATENDIMENTO E DEMANDA EM UMA UNIDADE DE PRONTO ATENDIMENTO DO CENTRO-NORTE DO ESTADO DE GOIÁS, BRASIL.
Authors: Sampaio Raiane Antunes , Soares Victor Hugo Cortes , Lago Vitória Gabriela Moura , De Araújo Lilhian Alves
Published: October 2022

O objetivo desse estudo foi caracterizar o atendimento e demanda na Unidade de Pronto Atendimento (UPA) do interior do Centro-Norte de Goiás no período de 2016 a 2018. Trata-se de uma pesquisa transversal, descritiva de caráter quantitativo, com coleta de dados secundários por meio de relatórios gerados do sistema de gestão em saúde – ICS. Os resultados indicam que 55,8% dos usuários atendidos na UPA são do sexo feminino e 44,2% do sexo masculino. Pode-se observar que durante os três anos analisados a maior demanda foi por atendimentos pouco urgente 59,3%, seguido de urgente 24,7%, não urgente 11,4%, muito urgente 4,3% e emergencial 0,2%. De forma geral, os dados apontam para uma UPA com poucos registros de encaminhamentos para outros serviços de saúde totalizando apenas 680 em três anos. Frente ao número considerável de casos pouco urgentes e não urgentes atendidos pela UPA do presente estudo, foi possível identificar que os usuários desconhecem sobre a estratificação de risco e a possibilidade ampla de atendimento satisfatório por meio da Atenção Primária à Saúde (APS) em casos não graves.
SÍNDROME ALCOÓLICA FETAL – CONSEQUÊNCIAS E DIAGNÓSTICO
Authors: Mota Ivanise Correia da Silva
Published: October 2022

A Síndrome Alcoólica Fetal (SAF) corresponde a um conjunto de sinais e sintomas presentes no concepto devido a ingestão excessiva de álcool durante a gestação. Suas manifestações consistem desde abortos espontâneos, malformações generalizadas, retardo mental e transtornos a interferências comportamentais. Devido ao escasso número de registros, este estudo objetivou clarear as características e diagnóstico da SAF, estabelecendo pormenorizadamente sua influência na vida da mulher atual. A metodologia aplicada foi de revisão da literatura através de livros, revistas específicas e bases eletrônicas Medline, LILACS, SciELO. Concluiu-se que a SAF é um problema de saúde pública, onde a mulher grávida deve ter consciência das consequências do abuso de álcool, evitando subdiagnóstico e incidência. É fundamental o desenvolvimento de programas específicos de alerta dos riscos, seja na gestação, seja na amamentação, frisando que a abstinência alcoólica é crucial para prevenção e eliminação de quaisquer danos ao feto exposto, independente da gesta anterior.

Palavras-chave: Alcoolismo. Consequências da SAF. Diagnóstico da SAF. Gestante. Síndrome alcoólica fetal.
ESTADO DA ARTE SOBRE DIARREIA INFANTIL COM ÊNFASE NA CRIANÇA QUILOMBOLA
Authors: Siqueira Samylla Maira Costa , De Camargo Climene Laura
Published: October 2022

Apresentar um levantamento da produção científica sobre diarreia infantil, dando ênfase à criança quilombola. Método: Trata-se de um estudo descritivo, do tipo Estado da Arte, realizado em junho de 2019 no catálogo de teses e dissertações da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, na Biblioteca Virtual em Saúde e na Scientific Electronic Library Online. Resultados: A busca resultou em 62 materiais. Observou-se que 56 destes trabalhos se relacionaram à diarreia infantil, mas nenhum tinha como público específico a criança quilombola. Conclusão: Dada a baixa produção científica acerca da diarreia infantil em comunidade quilombola identificada a partir deste estado da arte, se faz necessário estimular as publicações sobre este tema, visto ser a diarreia um importante agravo na infância, especialmente entre as crianças de núcleos vulneráveis, como é o caso dos quilombos.
2021 MDB Joint Report
Authors: Mesquita Moreira Mauricio , Dolabella Marcelo , Kwanghee Ko , Choi Hankyeung , Em Honggi , Choi Sungkyu , Kim Yongseok , Lee Da sol , Chicola Erica
Published: October 2022

The Joint Report on Multilateral Development Banks Climate Finance is an annual collaborative effort to publish multilateral development bank climate finance figures, together with a clear explanation of the methodologies for tracking this finance. This joint report, alongside the banks publication of climate finance statistics in their respective corporate media, is intended to track progress in relation to their climate finance targets such as those announced at COP21 and the greater ambition pledged for the post-2020 period.
SMART Management of Sustainable Development of the Region in the Context of Globalization
Authors: Kryshtanovych Svitlana , Kornieieva Tetiana , Malinovska Olga , Sokolik Larysa , Bortnikova Maryana
Published: October 2022

The main purpose of the study is to determine the main stages of SMART management of sustainable development of the region for the countries of Eastern Europe in the context of globalization. The issue of implementing a SMART management system today is relevant and critical for the further optimal functioning of the regional management system. The process of implementing SMART management itself is complex and complex, given this, there is a real need to find new methods for systematizing this process in the regional management system. The methodology involves the application of the method of graphic representation of the functional achievement of the goal. This methodology allows you to depict the main stages of achieving the goals in the beat way. Based on the results of the study, we have formed a graphically step-by-step model of effective SMART management of sustainable development of the region for the countries of Eastern Europe under the influence of globalization. As a result of the formation of this model, we have algorithmized and systematized the process of implementing SMART management of sustainable development of the region for the countries of Eastern Europe in the context of globalization. The use of this model will facilitate the adaptation of regional governance systems to a qualitatively new type of management. The study has limitations and concerns limited access to the socio-economic and sustainable development of the regions. We have taken only the regions of Eastern Europe as an example, but in the future we should expand our graphically step-by-step model of effective SMART management of sustainable development of the region for the countries of Eastern Europe under the influence of globalization for the regions of the whole world.
Principles for the Sustainable Design of Hospital Buildings
Authors: Alsawaf Ebtisam S. , Albadry Amjad M.
Published: October 2022

Technological progress has had negative effects as well as positive effects if it affects the life industry and the entire ecosystem significantly through the great consumption of natural resources, and here the construction sector in general and the health sector, in particular, have a role in this. From the perspective of keeping pace with technological development, responding to environmental changes, and paying attention to hospital environments (especially since the emergence of modern epidemics), and because the construction sector is the largest consumer of energy in the world, which made international organizations move towards creating a sustainable environment in the construction of hospital buildings by reducing energy consumption. This research focused on studying the components and principles of sustainable design for hospital buildings and the environmental, economic, health, and social benefits of sustainable development in the healthcare industry. In addition to the research objective, which is to build a model as a guide to guide health care officials interested in applying sustainable design principles in hospital design, to achieve an ideal sustainable hospital environment. To achieve this goal, a comprehensive theoretical framework was built by adopting a descriptive and analytical approach and extracting the most important vocabulary and effective indicators for sustainable design in hospitals.
Strengthening Community Participation in Spatial Planning of Riverflow Regions in Medan City
Authors: Thamrin Muhammad Husni , Ridho Hatta , Nasution Faiz Albar
Published: October 2022

Due to the impact of the flooding issues in Medan City, which are driven by the occurrence of sedimentation, narrowing, and law enforcement, it is required to offer alternate options for watershed management through a strategy to increase community involvement in spatial design. This study uses a qualitative, descriptive methodology. Techniques for gathering data include documentation, holding FGDs with seven stakeholders, and conducting in-depth interviews with riverside communities. According to the study's findings, Medan City's watershed management has not been carried out to its full potential through community participation. The situation gets worse as a result, as evidenced by the growth of riverbank communities, deteriorating water quality, poor health, and extensive floods. The primary issue that has to be fixed is the lack of communication between the community and the government. Low public knowledge and ineffective law enforcement in policing and securing river borders are barriers to community participation in spatial planning. This study suggests that pertinent organizations set up a watershed management coordination forum and educate and engage the local population in watershed management. This study offers a thorough understanding of how the quantity and quality of watersheds in Medan City are worsened by poor community participation.
Determination of the thermal state of the elements of a piston engine turbocharger
Authors: Zadorozhnaya E.A. , Hudyakov V.S. , Sibiryakov S.V. , Naprimerova E.D.
Published: October 2022

The power boost of heat engines is conditioned by the increase in the load on all its elements and related units. The turbocharger is one of the most common units that provide the power boost of a heat engine. The reliability of the turbocharger and its tribo-couplings guarantees the stable operation of not only it, but also the machine as a whole. An increase in the rotor speed leads to an increase in the thermal loading of the turbocharger elements. In this regard, timely assessment of the thermal state of the tribocoupling components, temperature distribution over the shaft, housing and other elements of the turbocharger is an urgent task. An algorithm for calculating heat transfer between the elements of a turbocharger has been developed, and an assessment of the heat load of radial multilayer plain bearings of a flexible asymmetric rotor has been made. The simulation was carried out in the ANSYS Fluent software package. The experimental data of the manufacturing plant were used as boundary conditions. The results of the calculation are given: the distribution of thermal fields in the turbocharger housing and the temperature in the area of ??the turbine and compressor plain bearings. Dependences of temperatures in the bearing area on the rotor speed are obtained. The calculation results were verified by comparing the temperatures in the turbine and compressor plain bearings with the data given in the publications of other authors. The temperature values in the outer and inner layers of the bearing were the initial data for calculating the dynamics of the turbocharger rotor, taking into account the thermal deformations of the tribocouple elements. The results of the research will be used to assess the stability of the movement of the rotor, the failure-free operation of the bearing assembly, as well as the reliability and durability of the turbocharger as a whole.
A Study on Rural Finance, Rural Industry Revitalization, and Rural Logistics Development: An Empirical Analysis Based on Panel Data from 30 Provinces in China
Authors:   IAGBT, Qin Zhuoping , Jin Xu
Published: October 2022

Purpose - This is a study on the influence mechanism of rural finance and rural industrial revitalization on rural logistics development from rural revitalization strategy.
Design/Methodology/Approach - We use panel data of 30 Chinese provinces from 2011 to 2020. A two-way fixed-effects model is constructed and mediated effects analysis and multiple regression analysis are used to analyze the dynamic relationship between rural finance, rural industrial revitalization, and rural logistics development. The dynamic relationship was empirically analyzed using mediated effects analysis and multiple regression analysis.
Findings - Rural finance has a significant positive impact on rural logistics, and rural finance effectively promotes rural logistics development; rural finance affects rural logistics development by influencing the revitalization of rural industries, indicating that the revitalization of rural industries plays a mediating effect. The impact of rural finance on rural logistics is heterogeneous in the east, central, and west. Rural industry revitalization does not play a mediating role in the central era, comparing with an obvious mediating role in the east and west.
Research Implications - The revitalization of rural industries as a transmission mechanism for rural finance to promote the development of rural logistics, and we verify the rationality of this transmission mechanism through a model to fill the gaps in the existing literature, thus providing a new research perspective for rural finance to promote the development of rural logistics, and providing some theoretical guidance and policy reference.
The Effects of Extended Technology-based Self-service on Passenger Satisfaction, Airport Image, and Behavioral Intention
Authors:   IAGBT, Lee Su-Yeon , Kim Yeong Gug
Published: October 2022

Purpose - This study examines the effects of Technology-Based Self-Service (TBSS) on passenger satisfaction, behavioral intention, and airport image, and analyzes the moderating effect of self-efficacy on the relationship between TBSS characteristics and passenger satisfaction.
Design/Methodology/Approach - The study uses the SPSS 26.0 and AMOS 26.0 statistical packages to analyze a sample of 238 passengers that used TBSS at Incheon International Airport (ICN). Characteristics in the categories of functionality, enjoyment, safety, and speed had positive effects on passenger satisfaction, and passenger satisfaction had a positive effect on airport image and behavioral intention.
Findings - No significant difference between the higher and lower self-efficacy groups was found in the relationship between TBSS characteristics and passenger satisfaction. The results suggest that airports employ marketing strategies that emphasize the TBSS characteristics of functionality, enjoyment, safety, and speed, particularly aspects of personal safety, including sanitation and hygiene.
Research Implications - The study shows that the industry should emphasize the value of TBSS in ensuring personal safety. The results of this study provide a theoretical basis for further research on service quality as it relates to the changing characteristics of TBSS in the post-pandemic era.
A Comparative Study of Korean and U.S. Firms amid COVID-19 Supply Chain Disruptions: The Role of Relational Capital for Improving Ambidextrous Innovation and Firm Performance
Authors:   IAGBT, Stephens Aaron Rae , Robb Charles Arthur , Kang Minhyo
Published: October 2022

Purpose - Supply chain disruptions have plagued firms since the advent of COVID-19 lockdowns. As a result, supply chains remain unstable and dynamic. To better understand supply chain management during periods of disruption, this study compares the impact of relational capital on ambidextrous innovation and firm performance between Korean and U.S firms.
Design/Methodology/Approach - This study includes a sample of 200 Korean firms and 227 U.S firms. PLS-SEM is the statistical tool utilized with MICOM multigroup analysis.
Findings - Korean and U.S. firms were found to be different on three different pathways indicating that open innovation and investment in supplier relations improve supply chain disruption orientation, exploration innovation, and firm performance
Research Implications - Relationship capital can significantly improve supply chain management, innovation, and firm performance. Exploitation innovation is better for enhancing supply chain management in the short-term amid interruptions.
Between Nomos and Physis
Authors: Eustacchi Francesca
Published: October 2022

Sophists deal with the problem of relationship between nomos and physis in terms not only of opposition between, but also of intertwinement. On the one side, the discussion leads to an exaltation of the physis, with opposite effects: in some sophists (Hippias and Antiphon) nature warrants the equality among human beings, while, in other sophists (Callicles and Thrasymachus), nature becomes the basis for legitimizing the dominance of the strongest over the weakest. In this context, the nomos is considered an invention of the weakest to inhibit the strongest. On the other side, we find sophists (like Gorgias) that affirm the need to decide to follow the nomos or the physis on the basis of situation, that is to avoid unilateral positions, or sophists (like Anonymous of Iamblichus) that assume a “conciliatory” perspective between nomos and physis. Socrates completes the variety of this debate. In Criton, Socrates applies a manifold movement to the nomos, divine and human, thus deserving respect and, at the same time, modifiable.
Enabling 4.6 V LiNi0.6Co0.2Mn0.2O2 cathodes with excellent structural stability: combining surface LiLaO2 self-assembly and subsurface La-pillar engineering
Authors: Yu Zhaozhe , Tong Qilin , Cheng Yan , Yang Ping , Zhao Guiquan , Li Huacheng , An Weifeng , Yan Dongliang , Lu Xia , Tian Bingbing
Published: October 2022

Although Ni-rich layered materials with the general formula LiNi1-x-yCoxMnyO2 (0 < x, y < 1, NCM) hold great promise as high-energy-density cathodes in commercial lithium-ion batteries, their practical application is greatly hampered by poor cyclability and safety. Herein, a LiNi0.6Co0.2Mn0.2O2 (NCM622) cathode modified with a surface self-assembling LiLaO2 coating and subsurface La pillars demonstrates stabilized cycling at 4.6 V. The LiLaO2-coated NCM622 benefits from the suppression of interfacial side reactions, which relieves the layer-to-rock salt phase transformation and therefore improves the capacity retention under high voltages. Moreover, the La dopant, as a pillar in the NCM622 lattice, plays a dual role in expanding the c lattice parameter to enhance the Li-ion diffusion capability, as well as suppressing Ni antisite defect formation upon cycling. Consequently, the dual-modified NCM622 cathode exhibits an initial Coulombic efficiency of over 85% and a high capacity of over 200 mAh g-1 at 0.1 C. A specific capacity of 188 mAh g-1 with a capacity retention of 76% is achieved at 1 C after 200 cycles within a voltage range of 3.0-4.6 V. These findings lay a solid foundation for the materials design and performance optimization of high-energy-density cathodes for Li-ion batteries.
Coquaternions, Metric Invariants of Biologic Systems and Malignant Transformations
Authors: Davydyan Garri
Published: October 2022

Different hypotheses of carcinogenesis have been proposed based on local genetic factors and physiologic mechanisms. It is assumed that changes of the metric invariants of a biologic system (BS) determine general mechanisms of cancer development. Numerous data demonstrate an existence of three invariant feedback patterns of BS: negative feedback (NFB), positive feedback (PFB) and reciprocal links (RL). These base patterns represent basis elements of a Lie algebra and imaginary part of coquaternion. Considering coquaternion as a model of a functional core of a BS, conditions of the system can be identified with the points of three families of hypersurfaces in R42: hyperboloids of one sheet, hyperboloids of two sheets and double-cones. Corresponding quadratic form relates negative and positive entropy contributions of base elements to the energy level of the system, so that anabolic states of the system will correspond to the points of a hyperboloid of one sheet, while catabolic conditions to the points of a hyperboloid of two sheets. Equilibrium states will lie in a double cone. Hypothetically anabolic and catabolic states dominate intermittently oscillating around the equilibrium. Deterioration of base elements increases positive entropy and causes domination of catabolic states which is the main metabolic determinant of cancer. Corresponding trajectory of a malfunctioning system will have a tendency to remain inside the double cone.
Targeting Envelope Proteins of Poxviruses to Repurpose Phytochemicals against Monkeypox: An In Silico Investigation
Authors: Gulati Pallavi , Chadha Jatin , Harjai Kusum , Singh Sandeepa
Published: October 2022

The monkeypox virus (MPXV) has become a major threat due to the increasing global caseload and the ongoing multi-country outbreak in non-endemic territories. Due to limited research in this avenue and the lack of intervention strategies, the present study was aimed to virtually screen bioactive phytochemicals against envelope proteins of MPXV via rigorous computational approaches. Molecular docking and molecular dynamic (MD) simulations were used to investigate the binding affinity of 12 phytochemicals against three envelope proteins of MPXV, viz., D13, A26, and H3. Silibinin, oleanolic acid, and ursolic acid were computationally identified as potential phytochemicals that showed strong binding affinity towards all the tested structural proteins of MPXV through molecular docking. The stability of the docked complexes was also confirmed by MD simulations. ADME analysis also computationally confirmed the drug-like properties of the phytochemicals, thereby asserting their suitability for consumption. Hence, this study envisions the candidature of bioactive phytochemicals as promising inhibitors against the MPXV, serving as template molecules that could further be experimentally evaluated for their efficacy against monkeypox.
Kaleidoscope States as a Statistical Mixture in the Jaynes-Cummings Model: Entropy and Purification
Authors: Anaya-Contreras Jorge , Zúñiga-Segundo Arturo , Moya Hector
Published: October 2022

We investigate some of the fundamental features of the interaction of mixed kaleidoscope states, namely, particular statistical mixtures of coherent states, with two-level atoms in the Jaynes-Cummings model framework. We begin our analysis by calculating the von Neumann entropy of the field which is determined with help of the virtual atom method. Oscillations appear in this entropy that indicate a state of purity greater than the initial state, {it i.e.}, a purification of the initial state is achieved. In this oscillatory region, we obtain the field Wigner function that resembles Schrodinger's cats.
CHRDL1 Regulates Stemness in Glioma Stem-Like Cells
Authors: Berglar Inka , Hehlgans Stephanie , Rödel Franz , Kögel Donat , Linder Benedikt
Published: October 2022

Glioblastoma (GBM) still presents as one of the most aggressive tumors in the brain, which despite enormous research efforts remains incurable until today. As many theories evolve around the persistent recurrence of this malignancy the assumption of a small population of cells with a stem-like phenotype remains as a key driver of its infiltrative nature. In this article we research Chordin-like 1 (CHRDL1), a secreted protein, as a potential key regulator of the glioma stem-like cell (GSC) phenotype. It has been shown that CHRDL1 antagonizes the function of Bone Morphogenic Protein 4 (BMP4), which induces GSC differentiation and hence reduces tumorigenicity. We therefore employed two previously described GSCs spheroid cultures and depleted them of CHRDL1 using stable transduction of a CHRDL1-targeting shRNA. We show with in vitro cell based assays (MTT, limiting dilution and sphere formation assays), western blots, irradiation procedures and quantitative real-time PCR that depletion of the secreted BMP4 antagonist CHRDL1 prominently decreases functional and molecular stemness traits resulting in enhanced radiation sensitivity. As a result, we postulate CHRDL1 as an enforcer of stemness in GSCs and find additional evidence that high CHRDL1-expression might also serve as a marker protein to determine BMP4-susceptibility.
PENGARUH EFIKASI DIRI DAN BIMBINGAN KARIR TERHADAP KESIAPAN KERJA SISWA KELAS X DAN XI SMK NEGERI DI JAKARTA
Authors: Zain Nuryetty , Marsofiyati  , Jeniar Ramadhanty
Published: October 2022

This study aims to determine whether there is an effect of self-efficacy and career guidance on work readiness of class X and XI students at one of SMK Negeri in Jakarta. The research method used was a survey method. The population in this study is 499 students and the sample is 202 students. Data on work readiness (Y), self-efficacy (X1), and career guidance (X2) are primary data using a Likert scale. The data analysis technique used is the first measurement of the outer model consisting of individual reliability with a result greater than 0.7 (> 0.7). Construct reliability with results greater than 0.7 (> 0.7). The composite reliability value is greater than 0.6 (> 0.6). AVE value is greater than 0.5 (> 0.5). The second measurement of the inner model consists of r2 with a value of 0.871. Then, f Square Self-Efficacy (X1) with a value of 0.594 and Career Guidance (X2) with a value of 0.477. Whereas the VIF value is smaller than (<5.00) so there is no multicollinearity problem. Self-efficacy coefficient (X1) of 0.808 and t statistics is 17.493> 1.971 with a p-value of 0.00 <0.05. Career Guidance Coefficient (X2) of 0.151 and t statistic that is 2.776> 1.971 with a p-value of 0.00 <0.05.
Triglyceride glucose-waist circumference to height ratio predicts 10-year diabetes risk: the REACTION research
Authors: Lin Jie , Gui Jing , Xiang Xin , Wan Qin
Published: October 2022

Objective: The aim of this research was to examine the causative association between TyG-WHtR and newly diagnosed diabetes.
Patients and measurements: We organized a retrospective 10-year cohort study of 10150 Chinese adults. After screening out people who were not qualified, the TyG-WHtR level of 7130 participants was calculated in this study. The Jonckheere-Terpstra test was performed to examine an increasing or decreasing trend across TyG-WHtR quartiles. Multivariate Cox regression models were used to investigate the possibility that it has a connection with diabetes.
Results: Within 10 years, 355 participates (4.98%) had new-onset diabetes. The TyG-WHtR index and newly diagnosed diabetes mellitus had a linear correlation, according to Cox regression analysis (HR = 2.798, 95% CI: 2.285 to 3.426, P < 0.001). In terms of sensitivity and specificity, the TyG-WHtR was found to be 73.52% and 62.60% accurate, respectively, with a 95% CI of 0.703–0.756. Additionally, TyG-WHtR-associated diabetes was substantially more prevalent in men, people aged 41 to 50, with a BMI below 18.5 kg/m2 and no hypertensive condition (P < 0.05).
Conclusions : TyG-WHtR might be an accurate indicator of future diabetes risk.
Application of soft computing approaches for modeling annular pressure loss of slim-hole wells in one of Iranian central oil fields
Authors: Jafarifar Iman , Abbasi Hassan , Kiani Mohammad
Published: October 2022

In order to have a better control over the drilling process and reduce the overall cost of this drilling operation, engineers have tried to use soft computing (SC) techniques to conduct the pre-estimation of drilling events. It is critically important to estimate the annular pressure losses (APL) for non-Newtonian drilling muds within annulus in order to specify pump rates and also to be able to choose the most appropriate mud pump systems while conducting the drilling operations. To develop the vigorous and exact models to enable the prediction of APL, two popular models were employed, i.e., multilayer perceptron (MLP) [optimized by levenberg-marquardt (LM), bayesian regularization (BR), scaled conjugate gradient (SCG), Resilient back propagation (RB), and broyden fletcher goldfarb shanno (BFGS)] and radial basis function (RBF). Subsequently, applying a committee machine intelligent system (CMIS), the four top models were combined into a unit paradigm. Several tools such as error distribution diagram, cross plot, trend analysis, and cumulative frequency diagram were used in conjunction with statistical calculation to assess the efficiency of models. Consequently, the CMIS model was introduced as the most exact technique which has the greatest coefficient of determination (R2 close to one) as well as the lowest root mean square error (RMSE close to zero) for the tested dataset.
CTLA4 + CD4 + CXCR5 - FOXP3 + T cells associate with unfavorable outcome in patients with chronic HBV infection
Authors: Wen Chunhua , Dong Zheyu , Wang Yiyue , Ye Guofu , Ma Yanchen , Yi Xuan , Zhou Yang , Li Xiaoyi , Zheng Xinchun , Hou Jinlin , Li Yongyin , Tang Libo
Published: October 2022

Background
Recently, a new subset of CD4+FOXP3+cells expressing CXCR5, which exhibits a unique phenotype and function, has been identified in viral infections. In contrast, the role of CD4+CXCR5−FOXP3+ T cells in patients with chronic HBV infection remains unclear.
Methods
Treatment-naïve chronic HBV-infected patients, HBV-related hepatic failure, and a longitudinal cohort of chronic hepatitis B (CHB) patients with nucleos(t)ide analogue treatment were enrolled for analysis of CD4+CXCR5−FOXP3+ T cell responses.
Results
Single-cell RNA sequencing (scRNA-seq) revealed that circulating CD4+CXCR5−FOXP3+ T cells presented distinct inhibitory features compared to spleen tissue. Meanwhile, patients with treatment-naïve chronic HBV infection or with HBV-related hepatic failure showed an upregulation of immune-suppressive features (PD-1, CTLA4, GITR) on CD4+CXCR5−FOXP3+T cells; in vitro analysis found HBeAg and HBcAg stimulation led to elevated levels of inhibitory molecules. Notably, the frequency of CTLA4+CD4+CXCR5−FOXP3+ T cells was positively correlated with HBV DNA levels, and longitudinal analysis demonstrated a high frequency of this subset at 12 weeks of antiviral treatment predicted unfavorable outcome in CHB patients.
Conclusions
The CTLA4+CD4+CXCR5FOXP3+ T cells, regulated by HBV antigens, are related to unfavorable outcomes in HBV-infected patients; these data indicated that alleviating CTLA4+CD4+CXCR5FOXP3+ T cells may improve the prognosis of HBV infection.