bluuebunny/crossref_metadata_2025 huggingface dataset:
Cardiovascular regulation in female students of northern university during extreme photoperiod seasons
Authors: Pogonysheva I. A. , Shalamova E. Yu. , Pogonyshev D. A. , Bochkarev M. V. , Ragozin O. N.
Published: November 2022

Objective. The aim of study was to assess the state of cardiovascular system in female students in the northern region during the seasons with extreme photoperiod. Design and methods. The study was conducted in Nizhnevartovsk, Khanty-Mansi Autonomous Okrug-Yugra (a region equated to the Far North) in the seasons with extreme values of photoperiod. The female students of Nizhnevartovsk State University (n = 73) aged 18-21 years were examined. Anthropometric measurements were carried out. Systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR) were recorded automatically using UA-101 model tonometer. Pulse and mean dynamic pressure were calculated according to Hickam's formula. On the basis of HR we determined the average duration of cardiac cycle. Autonomic tone was assessed according to calculated Kerdo index (KI). We used CardioVisor-06c to determine the prenosological state of cardiac activity. Results. There was a significant increase in body weight in the short daylight period. The HR during the long daylight period was significantly higher than during light deprivation, leading to a shorter cardiac cycle duration. Seasonal dynamics of blood pressure characteristics were not evident, although during “white nights” at least 10 % female students had SBP higher than 130 mm Hg, and maximal SBP reached 135 mm Hg. KI values demonstrated significant changes in autonomic tone. During short daylight hours average characteristics of KI were negative and reflected activity of parasympathetic activity. Increase of sympathetic influences was during longer daylight hours. During “biological twilight” “Myocardium” index was significantly lower than during white nights. During short daylight hours only 10 % students showed “Myocardium” index over normal values (15 %), while half of respondents had higher values during white nights. “Rhythm” index was normal during the short daylight hours and significantly higher during the long daylight hours, only 10 % participants had normal values. Conclusions. The analysis of electrophysiological parameters of myocardium showed seasonal changes in female students and “white nights” were associated with more negative effects than “biological twilight”. During “white nights” we showed increase in integral indices of dispersion mapping, increase in resting HR and KI.
Popular Stoicism in the Face of Social Uncertainty
Authors: Dopierała Renata
Published: November 2022

The article discusses popular Stoicism (a modern, simplified, and often commercialized version of ancient Stoicism), which is offered as an answer to the uncertainty of modernity. The financial, political, climate, and health crises have been detrimental to the sense of agency and control over one’s life, leading individuals to seek ways of (subjectively) regaining it. Popular Stoicism can be viewed as an expert system providing individuals with a specific vision of happiness and the good life, in addition to offering practical knowledge on how to define an area of individual agency by negotiating the boundaries between that which is within one’s power and that which is not. Reflections begin with a juxtaposition of ancient and contemporary Stoicism, focusing on their different socio-cultural origins, followed by a synthesis of the principles of ancient Stoicism on happiness and the good life and a detailed interpretation of the ‘offering’ of popular Stoicism in the relevant areas. In the latter context, two chosen Stoic exercises (necessary to achieve happiness and the good life) are discussed—the ability to recognize what things depend/do not depend on us and Stoic emotion work. The practices and techniques recommended as a part of constant work on oneself are also supposed to teach individuals to adapt to their unstable reality. As a result, the popular version of Stoicism perpetuates the mechanisms of the culture of individualism, which holds the individual fully responsible for their life, and the therapeutic and counseling culture (based on one’s readiness to constantly self-improve), which is a new form of disciplining in a neoliberal society. Both are important elements of the everyday life and lifestyle of the middle class. This class is interested in self-fulfillment and is the primary target audience of contemporary Stoic handbooks. The consideration is based on fragments of books on popular Stoicism, mainly written by Polish philosophers, subjected to qualitative content analysis.
The Physiology, Growth and Essential Oil Content of Lemon Balm (Melissa officinalis L.) in Response to Different LED Treatments
Authors: Mohamed Shiren Jalal
Published: November 2022

Background: Light-emitting diodes (LEDs) are a promising technology that has enormous potential to improve irradiance efficiency and to replace traditionally used horticultural lighting. Compared with traditional light sources (e.g., high-pressure sodium lamps and metal halide lamps) used in crop production, LEDs tends to have long life, generate less heat waste and providing the perfect spectrum for plant growth. Methods: This work sought to investigate the effect of using blue LED lights on growth and development in Lemon balm (Melissa officinalis L.) under sole-source LED lighting spectra. Lighting spectra were provided by differing combinations of LEDs of 4 different peak wavelengths, (Blue 435, Blue 450, Red 663 nm and Green 540 nm) with ratios of (1.95:2.3:1 R: G: B 450 nm (white), 5: 1R: B 450 nm, 2.5:1 R: B 450 nm and 2.5:1 R: B 435 nm) at a PPFD of 95 μmol m-2 s-1 (PAR). Result: showed that the blue light with a wavelength peak at 435 nm in combination with red light at 663 nm at the ratio of (2.5:1 R: B) and white LEDs enhanced the physiology of lemon balm (i.e., significantly increased assimilation rate, stomatal conductance and transpiration rate), consequently fresh and dry shoot weight increased and the shoot essential oil content.
Betamethasone Toxicity Induced by Topical Maternal Exposure Prior to Fertilization in Heart of Newborn Rabbits
Authors: Nwaiser Fatemah Al , Bekht Gamal , Sedky Azza
Published: November 2022

Background: Betamethasone treatment is widely used and recommended worldwide. Although, there are no enough studies to look for the risk or potential alterations due to accumulation of this drug before fertilization. In addition, previous studies payed attention to intramuscular injection during pregnancy neglecting the long-term impact of the use of topical solutions. So, the aim of the present study was to determine this side effect. Methods: We used two doses of betamethasone: 0.02 and 0.2 mg/Kg b.w. were and at the end of the experimental period (after 3 weeks of delivery), six new-born rabbits of both sexes (1 new born rabbit per mother) were dissected under light anesthesia and heart samples were collected. All the measurements were performed in one assay. Result: The results of this study revealed maternal exposure to betamethasone prior to fertilization, induced oxidative stress, alterations in levels of enzymes. Furthermore, these biochemical alterations were supported by histopathological and ultrastructural observations. So, this study suggested that females; desiring to be pregnant, should stop treatment of psoriasis with betamethasone before fertilization to avoid heart toxicity of their offspring.
Management Strategies using Phytoextracts and Fungicides Against Cercospora Leaf Spot of Mungbean Incited by Cercospora canescens under in vitro and in vivo Conditions
Authors: Kumar Naresh , Singh Mahabeer , Lakhran Lalita , Prajapati Satyadev , Maurya Shivam
Published: November 2022

Background: Cercospora leaf spot of mungbean [Vigna radiata (L.)] caused by Cercospora canescens. It has become a severe menace to the growers of Rajasthan in India and in general causes economic losses under changing climatic scenario. Depending upon the temperature and humidity, it spreads rapidly in susceptible varieties causing premature defoliation and reduction in size of pods and grains. In this study management was taken through botanicals and fungicides is also an important segment in the present era, in view of hazards caused by toxic chemicals or being developed resistance in pathogens to fungicides and effective means for disease control. Methods: In this field-laboratory investigation during kharif 2018 and kharif 2019 at Agronomy Farm, Sri Karan Narendra Agriculture University, Jobner, Jaipur, Rajasthan. The experiment was conducted for seven plant extracts at 5, 10 and 15 per cent concentrations were evaluated in vitro by poisoned food technique. In field experiments, further these fungicides applied as different concentrations viz., 0.1, 0.2 and 0.3% and plant extracts (at 10% conc.) were assessed by two foliar applications to control the disease. Result: Experiment was carried out in laboratory and field condition. In Plant extracts, the 100 per cent inhibition of mycelial growth was obtained with garlic extract at 10% concentration. In field conditions, two foliar applications of Hexaconazole (0.1%) were proved the most effective in reducing disease intensity (55.58%) and in increasing crop yield (56.50%) followed by Hexaconazole + Captan. In plant extracts, garlic extract (10%) proved superior in reducing disease intensity (52.85%) and in increasing crop yield (33.96%) followed by neem leaf extract.
The Effects of Angiotensin II, Olmesartan and PD123,319 on Protein Kinase C in STZ Induced Rat Vascular Smooth Muscle Cell Culture
Authors: ÇİÇEK Zehra , AKILLIOĞLU Kübra , DOĞAN Ayşe
Published: November 2022

Protein kinase C (PKC) is a promoter enzyme that plays a vital role in signal transduction of vascular smooth muscle cells (VSMCs). It has numerous vascular functions, such as vascular cell growth, cytokine activation and angiogenesis. But, these mechanisms are deteriorating in diabetes mellitus. Angiotensin II (Ang II) effects on vascular structure binding Ang II type-1 and type-2 receptors (ATR1 and ATR2) and stimulates PKC mostly through ATR1s. We aim to investigate the effects of Ang II, Olmesartan and PD123,319 on PKC levels of healthy and streptozotocin (STZ) induced rat VSMCs (H-VSMCs and STZ-VSMCs) in this study. The primary culture of VSMCs were isolated from thoracic aorta of healthy and STZ (45 mg/kg, given via the tail vein) induced Wistar rats. PKC levels were measured in H-VSMCs and STZ-VSMCs by enzyme-linked immunosorbent assay (ELISA). In H-VSMCs, Ang II group compared to the control group, PKC levels decreased significantly (P = 0.000); whereas, Ang II group compared to control, PKC levels were higher, but not significantly in STZ-VSMCs (P = 0.088). PKC levels were increased in Ang II+Olmesartan (P = 0.000) and Ang II+PD123,319 (P = 0.000) groups compared to Ang II group in H-VSMCs, but in STZ-VSMCs, PKC levels in Ang II+Olmesartan (P = 0.001) and Ang II+PD123,319 (P = 0.000) groups compared to Ang II group were decreased significantly. Ang II, its receptors and PKC seem to modulate each other and may have a relationship in hyperglycemic conditions. Also, considering that, ATR1 blocker (ATR1B) Olmesartan and ATR2 blocker (ATR2B) PD123,319 may be protective against vascular injury by reducing PKC levels in STZ-VSMCs.
Sobre la presencia de éros en Eurípides
Authors: López Férez Juan Antonio
Published: November 2022

Érōs, érōtos, de la misma raíz que éramai, registrado en griego desde Homero, con escasa presencia en los poemas homéricos, incrementa mucho los usos en los líricos y es bastante utilizado por los trágicos. Eurípides lo recoge en 79 ocasiones: 47, en obras conservadas; más 32 en fragmentos. En este trabajosólo me ocuparé de los ejemplos donde érōs está relacionado con la pasiónamorosa o con el dios Eros, haciendo una selección de los pasajes más relevantes, traducidos al español y acompañados de un comentario centrado en el sustantivo revisado. En nuestra lengua no existe ningún estudio completo dedicado a dicho objetivo, por lo que le podría interesar al lector del trágico, tanto en lo referente a dicho dios como en lo pertinente a la pasión amorosa.
Cómodo y una decisión estratégica: el fin de la expeditio Germanica en 180
Authors: Sáez Geoffroy Andrés
Published: November 2022

Cómodo ha sido visto como un emperador disoluto que lanzó por el despeñadero los logros del Siglo de Oro de los Antoninos. En el presente artículo intentaremos analizar una de las primeras decisiones que tuvo que tomar el joven emperador: proseguir o terminar las campañas dirigidas por Marco Aurelio. Sostendremos a lo largo de este trabajo que las decisiones estratégicas y militares de Cómodo fueron racionales en relación con el pensamiento militar romano del siglo II, aportando al debate historiográfico una nueva visión sobre dicho gobernante y la toma de decisiones por parte de los emperadores.
Dos cartas neolatinas inéditas entre los humanistas Lorenzo Ramírez de Prado (1583-1658) e Isaac Casaubon (1559-1614). Edición, traducción y comentario
Authors: Ballesteros Sánchez Juan Ramón
Published: November 2022

El texto ofrece la primera edición, traducción castellana y comentario de dos cartas neolatinas intercambiadas entre Lorenzo Ramírez de Prado (1583-1658) e Isaac Casaubon (1559-1614). Estas cartas fueron las primeras que se enviaron sus autores. Su estudio ilustra los mecanismos por medio de los cuales se constituyó la República de las Letras en el Humanismo tardío y permite reconstruir la relación entre ambos eruditos.
Cuatro casos de etimología poética en Heródoto: Los nomina loquentia de Bato, Crío, Demarato y Cípselo
Authors: Berruecos Frank Bernardo
Published: November 2022

Este estudio intentará demostrar cómo, a lo largo de las Historias de Heródoto, los nombres propios tienen una función narrativa importante y constituyen no sólo un recurso prominente del arte literario del autor, sino también de su método de concatenación y ordenamiento de la información. Los significados de los nombres funcionan como microrrelatos paralelos al relato en que se insertan y contribuyen a estructurar algunos elementos de la configuración histórica de la narración. Después de algunas reflexiones sobre los inicios de la filología en las Historias y sobre cómo los juegos etimológicos constituyen una prolongación y un complemento de la vocación filológica del historiador, se presentarán cuatro casos de nomina loquentia en los que los nombres funcionan como cápsulas de significación que articulan literariamente ciertos episodios de la narrativa histórica y ayudan a jerarquizar e interpretar las distintas versionesde los acontecimientos.
La peste del tirano Edipo: política, medicina y desmesura
Authors: García Pérez David
Published: November 2022

En este trabajo se expone la relación temática entre la política y la medicina que es posible discernir en el Edipo tirano de Sófocles. El hilo conductor entre ambas disciplinas (τέχναι) es el concepto de desmesura (ὕβρις) como causa de la peste que asoló la región del Ática en el 430 a. C., de acuerdo con la disposición trágica del mito de Edipo. Para tal fin, se recurre a Tucídides como fuente histórica, lo que permite un acercamiento a la tragedia de Sófocles desde la historiografía y, de este modo, se argumenta la configuración del Edipo como tirano; un concepto estrechamente enlazado con el tema de la pandemia referida.
La antonimia léxica en los epigramas funerarios áticos del siglo IV a. C.
Authors: Arteaga Conde Evelia
Published: November 2022

En el presente texto se analizarán diferentes clases de antonimia léxica en algunos epigramas funerarios áticos del siglo IV a. C. con el objetivo de mostrar que fue un recurso esencial en el desarrollo de un estilo propio. El análisis de estas antonimias léxicas se dividirá en dos ámbitos (sin implicar que sean los únicos que las presentan): el que destaca lo que el difunto hizo y dejó en esta vida, y el que hace énfasis en alguna cuestión del Más Allá. A través de este análisis se verá que dichas oposiciones reflejan formas de concebir la existencia y de actuar en ella.
Development of a map of rural settlements of the Russian population of the Tara County in the 16th–19th centuries
Authors: Sokolova Evgenia V.
Published: November 2022

The purpose of the research is to identify the factors that determine the process of forming a map of rural settlements of the Tara County in the 16th – 19th centuries and stages of development and settlement of the territory. Among the factors, the author singles out the policy of the state in the field of settling Siberia in general and the Tara County in particular, and the desire of peasants to develop new territories in search of solid arable land. The stages of the emergence of new Russian villages on the map of the Irtysh region are revealed: late 16th century –early 17th century, when the main task was to defend the borders of the territory; 17th – the first half of the 19th century, when the growth of the Siberian population led to an increase in the need for bread and, as a result, the need to develop new lands; the second half of the 19th century, when the emergence of new settlements is the result of the state's resettlement policy. We analyze different points of view on the appearance of new villages on the map, their placement relative to the old-timers' territories. The results of the study will be useful and interesting to scientists involved in the study of rural history, teachers of educational organizations of all levels of education and a wide range of readers who are passionate about the history of the Fatherland.
PENGARUH PENGGUNAAN HANDOUT DIGITAL PADA SUB KONSEP HEWAN VERTEBRATA TERHADAP HASIL BELAJAR PESERTA DIDIK
Authors: Rusminah Rusminah , Kaspul Kaspul , Utami Nurul Hidayati
Published: November 2022

Vertebrate Animals sub-concept learning involves the characteristics of vertebrates in each class and requires learning materials to overcome students' difficulties. Digital handouts are one of the teaching materials made to facilitate the delivery of material during the learning process, which includes teaching materials, questions, and independent practical instructions that can be used for online and offline learning. This research method uses a quasi-experimental or quasi-experiment to test the effect of using digital handouts on learning outcomes and student responses to the Vertebrate Animal sub-concept. The sampling of this research was carried out by random sampling technique in class X SMAN 4 Banjarmasin, which later became the research sample of 48 students in the experimental class (X MIPA 1) and the control class (X MIPA 2). The learning outcomes data were tested with the SPSS 21 program using the Wilcoxon Signed Ranks Test, while the student responses were analyzed descriptively. The research results, namely, student learning outcomes, indicate that the use of digital handouts affects learning outcomes with the Asymp value. Sig. (2-tailed) of 0.000<0.05. In addition, students' responses to the use of digital handouts received a positive response in classroom learning with an average of 80.57%, which included the category of strongly agree.Pembelajaran sub konsep Hewan Vertebrata melibatkan ciri karakteristik vertebrata pada setiap kelasnya dan memerlukan bahan pembelajaran untuk mengatasi kesulitan peserta didik. Handout digital merupakan salah satu bahan ajar yang dibuat untuk dapat mempermudah penyampaian materi pada saat proses pembelajaran yang memuat materi bahan ajar, soal-soal, dan petunjuk praktikum mandiri yang dapat digunakan untuk pembelajaran secara daring maupun luring. Metode penelitian ini menggunakan metode eksperimen semu atau Quasi Experimen dengan tujuan untuk menguji pengaruh penggunaan handout digital terhadap hasil belajar dan respon peserta didik pada sub konsep Hewan Vertebrata. Pengambilan sampel penelitian ini dilakukan dengan teknik random sampling di kelas X SMAN 4 Banjarmasin yang kemudian menjadi sampel penelitian sebesar 48 peserta didik kelas eksperimen (X MIPA 1) dan kelas kontrol (X MIPA 2). Data hasil belajar diuji dengan program SPSS 21 menggunakan Uji Wilcoxon Signed Ranks Test, sedangkan respon peserta didik dianalisis secara deskriptif. Dari hasil penelitian yang diperoleh yaitu hasil belajar peserta didik menunjukkan bahwa penggunaan handout digital berpengaruh terhadap hasil belajar dengan nilai Asymp. Sig. (2-tailed) sebesar 0.000<0,05. Selain itu, respon peserta didik terhadap penggunaan handout digital mendapatkan respon yang positif dalam pembelajaran di kelas dengan rata-rata 80,57% yang termasuk kategori sangat setuju.
PENGEMBANGAN ALAT UKUR SUHU BERBASIS MIKROKONTROLER ARDUINO NANO SEBAGAI MEDIA PEMBELAJARAN PADA MATERI SUHU DAN KALOR
Authors: Detasari Ade Tri , Hadiati Soka , Sukadi Eti
Published: November 2022

The development of temperature measuring instruments based on the Arduino nano microcontroler as a learning medium for temperature and heat materials aims to determine the feasibility based on the assessment of media experts and material experts and to determine student responses to its use. This study uses a 4D model consisting of data analysis stage, product design stage, product manufacturing stage and product validation and testing stages. This study tested the feasibility of learning media and the concept of temperature and heat by 2 media xpert validators and 1 material expert validator. In addition, this study also looked at student responses from 29 students at SMA Negeri 1 Sepauk, Sintang Regency to the use of learning media developed using a questionnaire. Based on the results of the assessment carried out by the media expert validator, it can be concluded that the temperature measuring instrument based on the Arduino nano microcontroler as a learning medium on temperature and heat material obtained an average score of 89.55% with a very feasible category and the results of the assessment carried out by the material expert validator obtained an average score of 87.5% with a very appropriate category. Student responses to the use of learning media obtained an average score of 90.8% with the category strongly agree.Pengembangan alat ukur suhu berbasis mikrokontroler arduino nano sebagai media pembelajaran pada materi suhu dan kalor bertujuan untuk mengetahui kelayakan berdasarkan penilaian ahli media dan ahli materi serta untuk mengetahui respon siswa terhadap penggunaannya. Penelitian ini menggunakan model 4D yang terdiri tahap analisis data, tahap desain produk, tahap pembuatan produk dan tahap validasi dan uji coba produk. Penelitian ini menguji kelayakan media pembelajaran dan kesesuaian konsep materi suhu dan kalor oleh 2 validator ahli media dan 1 validator ahli materi. Selain itu, penelitian ini juga melihat respon siswa dari 29 siswa di SMA Negeri 1 Sepauk Kabupaten Sintang terhadap penggunaan media pembelajaran yang dikembangkan menggunakan kuesioner. Berdasarkan hasil penilaian yang dilakukan oleh validator ahli media dapat disimpulkan bahwa alat ukur suhu berbasis mikrokontroler arduino nano sebagai media pembelajaran pada materi suhu dan kalor diperoleh skor rata-rata 89,55 % dengan kategori sangat layak dan hasil penilaian yang dilakukan oleh validator ahli materi memperoleh skor rata-rata 87,5 % dengan kategori sangat sesuai. Respon siswa terhadap penggunaan media pembelajaran memperoleh skor rata-rata 90,8 % dengan kategori sangat setuju.
HASIL GUNA PENILAIAN PADA PEMBELAJARA PJOK DI SMPN 1 BANJARBARU
Authors: Maulida Siti , Rahmadi Rahmadi , Hamid Abdul
Published: November 2022

Pada penelitian ini peneliti memiliki tujuan untuk mengetahui hasil guna penilaian pada pembelajaran PJOK hanya sampai dengan rapot atau di arah kan ke prestasi  pada peserta didik di SMPN 1 Banjarbaru. Penelitian ini menggunakan penelitian kuanlitatif dengan metode ex post facto  Sampel dari penelitian adalah guru PJOK di SMP Negeri 1 Banjarbaru sebanyak 4 orang. Pada penelitian ini peneliti menggunakan analisis data yaitu statistic deskriptif yang disajikan dalam presentasi. Teknik Sampel yang digunakan Sampling Purposive dengan pertimbangan SMPN 1 merupakan sekolah favorit di Banjarbaru. Pada penelitian ini maka didapatkan hasil guna atau manfaat penilaian hasil belajar pada mata pelajaran PJOK di SMPN 1 Kota Banjarbaru bahwa tidak terlaksananya atau tidak ada tindak lanjut ke arah prestasi bagi siswa yang mendapatkan penilaian bagus dalam pembelajaran PJOK.
PANDUAN PENILAIAN ASPEK AFEKTIF DAN ASPEK PSIKOMOTOR PADA MATA PELAJARAN PJOK DENGAN METODE HYBRID-LEARNING DI SMP NEGERI 1 BANJARBARU
Authors: Awalin Munasya Nur , Rahmadi Rahmadi , Hamid Abdul
Published: November 2022

Penelitian ini memiliki tujuan untuk mengetahui apakah guru PJOK memiliki panduan penilaian aspek afektif dan aspek psikomotor pada mata pelajaran pjok dengan metode hybrid-learning. Penelitian ini memakai metode penelitian kuantitatif. Sampelnya ialah guru PJOK SMP Negeri 1 Banjarbaru sebanyak 4 orang. Analisis data menggunakan statistik deskriptif yang disajikan dalam presentase. Teknik Sampel yang digunakan adalah Total Sampling. Dari kesimpulan penelitian ini dapat disimpulkan bahwa guru PJOK di SMP Negeri 1 Banjarbaru sudah memiliki panduan penilaian aspek afektif dan aspek psikomotor saat pembelajaran dengan metode hybrid-learning, tetapi guru masih belum bisa membuktikan secara autentik terhadap dokumentasi tersebut.
Polyadic rings of p-adic integers
Authors: Duplij Steven
Published: November 2022

In this note we, first, recall that the sets of all representatives of some special ordinary residue classes become $\left( m,n\right) $-rings. Second, we introduce a possible $p$-adic analog of the residue class modulo a $p$-adic integer. Then, we find the relations which determine, when the representatives form a $\left( m,n\right) $-ring.
Curcumin and Its Affection for Sleep Deprivation
Authors: Pandey Ramendra , Kumar Rohit
Published: November 2022

In this review, the following information describes the manifestation of sleep deprivation by human beings and its adverse effect on their health. Sleep deprivation has been demonstrated into namely two types known as REM sleep and NREM sleep affecting our health in so a problematic way that it is making our body immune to many diseases leading to lethal problems. Therefore, great research by many scientists has discovered that the turmeric “Curcuma longa” which is been used in every Indian kitchen since ancient times, has shown a remarkable effect on the problem caused by sleep deprivation but due to its poor solubility and low bioavailability drawn it into a great disadvantage. But the help of the study of nanotechnology and the evolution of curcumin into nano–curcumin made the possibility of the remarkable effect by making the curcumin more potent and enhancing its stability. Immunological changes due to sleep deprivation lead to Alzheimer’s disease, glioma, neuropathic pains, and many more. Therefore, this review has been summarized as it is been providing information related to curcumin and its affection for sleep deprivation.
Small-Scale Mechanical Recycling of Solid Plastic Wastes: A Review of PET, PEs, and PP
Authors: Uzosike Canice Chibuike , Yee Lachlan Hartley , Padilla Ricardo Vasquez
Published: November 2022

Mechanical recycling of solid plastic wastes on a small-scale level can be accomplished with the correct approaches. Thermoplastics are mostly considered for mechanical recycling because of their physical properties and ease of reprocessing. This paper reviews the mechanical reprocessing techniques of selected thermoplastics (polyethylene terephthalate and polyolefins) since they constitute a significant proportion of plastics used commercially. Furthermore, necessary considerations for effective operation of small-scale plants, including energy requirements of machinery and optimisation in order to improve efficiency and product quality, are discussed. A clearer understanding and addressing of the process-related challenges will lead to successful establishment and management of small-scale mechanical recycling facilities to benefit communities. Efficient small-scale mechanical reprocessing establishments have become essential in reducing the environmental impacts of solid plastic wastes and for energy conservation.
Social Disparities in the Duration of Power and Piped Water Outages in Texas After Winter Storm Uri
Authors: Grineski Sara E. , Collins Timothy W. , Chakraborty Jayajit , Goodwin Eric , Aun Jacob , Ramos Kevin D.
Published: November 2022

We assessed sociodemographic disparities in basic service disruptions caused by Winter Storm Uri in Texas. We collected data through a bilingual telephone survey conducted in July 2021 (n  = 753). Being Black, having children, and renting one’s residence were associated with longer power outage durations; being Black was also associated with longer water outages. Our findings highlight the need to plan for and ameliorate inequitable service outages and their attendant health risks in climate change–related extreme weather events such as Uri. (Am J Public Health. 2023;113(1):30–34. https://doi.org/10.2105/AJPH.2022.307110 )
Fetal Macrosomia
Authors:   Professor and Head, Department of OBGY, ACPM Medical College, Dhule424001, Maharashtra, India., Patil Alka , Kulkarni Nitin ,   Associate Professor, Department of OBGY, ACPM Medical College, Dhule424001, Maharashtra, India., Patel Richa ,   Senior Resident, Department of OBGY, ACPM Medical College, Dhule424001, Maharashtra, India.
Published: November 2022

Preconceptional, conception, antenatal period and intrapartum period are in continuum. For successful obstetric outcome, prepregnancy weight and proper antenatal care are important factors. Newborn whose birthweight exceeds 40004500gms is labled as macrosomia. Prolong labour, arrest of labour, foetal distress, shoulder dystocia, instrumental delivery and increased incidence of cesarean section are associated with macrosomic fetuses. Early detection, watchfull expectancy active interventions are key factors for safe delivery of macrosomic fetuses.
Study of Stripping of Membranes at Term Gestation to Reduce Post-Term Pregnancies
Authors:   Associate Professor, Department of Obstetrics and Gynaecology, ACPM Medical College, Dhule 424001 Maharshtra, India., Kulkarni Nitin , Patel Richa ,   Senior Resident, Department of Obstetrics and Gynaecology, ACPM Medical College, Dhule 424001 Maharshtra, India.
Published: November 2022

Introduction: Any pregnancy which has passed beyond the expected date of delivery is called a prolonged pregnancy & which have passed 42 weeks, 294 days is called postmaturity or post term pregnany [1], these are at an increased risk for fetal postmaturity syndrome, macrosomia, fetal intolerance of labor, oligohydramnios, meconium-stained amniotic fluid, and cesarean delivery [2]. The clinical evidence of an increased potential for these poor perinatal outcomes has triggered a movement toward increased antenatal testing between 37- 42 weeks of gestation, and cervical ripening with labor inductions at or before 42 weeks of gestation. While a ripe cervix is usually suggestive of fetal maturity to find an unripe cervix does not exclude maturity. Induction of labor is one of the most common procedures in obstetrics and is carried out in approximately 20% of pregnancies [3]. Mechanical and biochemical means have been used to affect cervical ripening and to induce labor. Methods of induction include amniotomy, membrane stripping or sweeping, prostaglandins, laminaria and oxytocin. Membrane stripping or sweeping is a commonly use procedure aimed at preventing the post term pregnancy and avoid the application of formal method of induction of labour. Aims and Objectives: 1. to determine the effectiveness & safety of membrane stripping at term pregnancy as a OPD procedure weekly which can reduce the incidence of Post term pregnancy, labour induction and its complication. 2. To determine what factors occurring after digital separation of the chorionic membranes from the lower uterine segment (membrane stripping) are involved in observed clinical changes compared with patients not so treated. Material and Methods: Study Design: This was a prospective study conducted at department of Obstetrics and Gynaecology at our hospital. Study Duration: Study was conducted during the period of duration September 2014 to September 2016. Results: After documenting the confirm gestational dating criteria and obtaining inform consent 200 patients at 37 complete week of gestation were randomly selected for the study. Data were collected from findings at 1,2,3 week and during labour, which is compaired by pearson chi-square and fischer exact test. Conclusion: Stripping of membranes is a very old procedure. This causes the release of plasma prostaglandin F2, Increase in endocervical phospholipase A activity and oxytocin release have also been observed. This will initiate uterine contraction and onset of labour. It is safe, cheap, effective and even an out patient procedure. It is associated with earlier delivery and decreased incidence of posterm gestation and hence maternal and fetal complication related to post maturity.
Crack Coalescence Behavior of Rock-Like Specimens Containing Two Circular Embedded Flaws
Authors: Bi Jing , Tang Jincai , Wang Chaolin , Quan Daguo , Teng Mingyang
Published: November 2022

Experimental research on the growth of internal flaws has rarely been reported due to the fact that it is difficult to cut internal flaws in specimens and cannot capture the initiation and propagation processes of internal flaws through direct observations. This paper proposed a method for creating internal flaws in specimens by utilizing the volatilization of camphor. A series of compression tests were performed on rock-like specimens including two embedded circular flaws, and CT techniques were used to investigate the internal damage behavior of flawed specimens. Experimental results illustrate that the strength and deformation properties of flawed specimens increase nonlinearly with the confining pressure as well as flaw inclination angle. Crack coalescence patterns and failure modes of flawed specimens depend on not only the confining pressure but also the flaw inclination angle. The crack coalescence pattern varies from wing crack coalescence to mixed tension-shear crack coalescence and then to the shear crack coalescence as the crack inclination angle increases. Confining pressure contributes to shear crack growth and has an inhibiting effect on the propagation of tension cracks. For specimens with the same flaw inclination angle, the failure mode changed from tension failure to mixed shear-tension failure or from mixed shear-tension failure to pure shear failure with the increase of confining pressure.
Rough River Dam Safety Modification Project Evolution
Authors: Shifflett Steven , Ailstock Will
Published: November 2022

This paper is a case study documenting how the Rough River Dam Safety Modification Project evolved over time. Rough River Dam is an embankment dam located in west-central Kentucky that is owned and operated by the U.S. Army Corps of Engineers (USACE) for flood risk management. The project has a right abutment cut-and-cover outlet conduit founded upon karstic limestone. In 2012, a Dam Safety Modification Report (DSMR) was completed that identified multiple internal erosion-related potential failure modes requiring mitigation. The DSMR recommended a multi-phased approach. The Phase I project included construction of a work platform in order to perform exploratory drilling and grouting for two partial grout lines. The Phase II project was to consist of grout line completion, construction of a full-length cutoff wall over and around the existing outlet conduit, grouting within the outlet conduit, and construction of a downstream filter. Based on encountered conditions, the Phase I grouting contract was modified to complete both partial grout lines for slurry control prior to cutoff wall construction. During design of the Phase II cutoff wall, the existing outlet conduit was determined to be structurally inadequate to support the cutoff wall. A Supplemental DSMR recommended a new left abutment outlet works to permit the existing conduit to be severed and to allow for construction of the full cutoff wall across the dam foundation. The Phase II design was completed in the fall of 2021. This paper summarizes the key information, findings, and decisions that informed the final direction of the project.
Analysis of Perforation Erosion Through Computational Fluid Dynamic Modeling
Authors: Zhang Yiming , Wang John Yilin
Published: November 2022

Field and experimental data have shown that perforation erosion during shale gas stimulation invalidates the assumption of a constant coefficient of discharge. However, perforation erosion is not fully understood yet. In this work, a perforation erosion model was built using computational fluid dynamics (CFD) and validated against laboratory data. We then conducted parametric studies to investigate the impact of treatment rate, proppant concentration, proppant size, and fluid viscosity on perforation erosion. Our results demonstrated that a higher treatment rate and larger proppant lead to higher erosion to the perforation diameter. Perforation erosion decreased when fluid viscosities increased from 10 to 100 cp, and then increased when the fluid viscosity was increased to 1,000 cp. Our new understandings could be applied to improve perforation design in shale wells.
A new firefly algorithm with an improved attractiveness module
Authors: Liu Jianxun , Shi Jinfei , Hao Fei , Dai Min , Zhang Zhisheng
Published: November 2022

Firefly algorithm(FA) is a very classic meta-heuristic algorithm, which is widely used in various fields to solve complex continuous optimization problems. However, in the actual engineering optimization process, the global optimization efficiency and convergence behavior of the FA need to be further improved. Therefore, we conducted modular research on the firefly algorithm and found that the attraction module of the FA has the problem of losing its attraction to distant fireflies. In order to improve the problem, an improved attractiveness module is proposed by the paper. The improved attractiveness module still has obvious attractiveness for long-distance fireflies. In order to enhance the exploration efficiency of the FA, the new firefly algorithm with an improved attractiveness module(IAM-FA) introduces a logarithmic spiral path. The IAM-FA contains 4 undetermined parameters. The four optimal parameters are determined through simulation.In the experiments on 20 benchmark functions and 4 real design cases, the IAM-FA shows excellent performance compared with other variant algorithms.
Prediction of recurrence of HCC after TACE using enhanced CT heterogeneity assessment
Authors: Wang Ru , Kou Qiqi , Dou Lina
Published: November 2022

Purpose: To evaluate the value of enhanced computed tomography（CT）heterogeneity in predicting early recurrence of patients with hepatocellular carcinoma (HCC) after transarterial chemoembolization (TACE).
Methods: Forty-seven HCC patients (40M/7F) were included in the study. Tumor histogram and texture analysis were performed on contrast-enhanced CT imaging prior to TACE. The clinical diagnosis of HCC at recurrent stages was based on the criteria of the American Association for the Study of Liver Diseases (AASLD) or biopsy. Two parameters of HCC heterogeneity (histogram and texture) were compared in the Early Recurrence (ER) and the Non-Early Recurrence (Non-ER) groups. Analysis was applied to both single-slice ROI and whole-tumor volumetric VOI. Receiver operating characteristic (ROC）was calculated to determine the ability of the parameters to differentiate between ER and non-ER groups.
Results: 27 patients with ER and 20 patients with NER. The largest diameters of tumors in ER group were significantly larger than NER group( P＜0.001). Texture results for ROI and VOI analyses were similar. In the histogram analysis, the 50th percentile of pixel intensity predicted early recurrence with a sensitivity (Se) of 92.6%. In texture analysis, entropy, mean, and inhomogeneity were significantly associated with early recurrence( P＜0.05) but not skewness and kurtosis (P＞0.05). Inhomogeneity had the highest diagnostic specificity (95%).
Conclusions: This study shows that CT histogram and texture features are significantly different in ER group from Non-ER Group.
Molecular Finger Printing of Thirteen Pakistani Mid-season Mango (Mangifera Indica L.) Varieties by Using Ssr Markers
Authors: Rauf Sheeba , Sharif Hamza , Babar Muhammad , Gul Almass , Shaukat Faiza , Bukhari Birra , Mehvish Ambreen , Raza Samad , Kiran Sidra , Qureshi Muhammad Ahsan , Sharif Naseem , Bukhari Syed Inam Ullah Shah
Published: November 2022

Present study was performed to identify the genetic make-up of thirteen mid-season mango verities i.e.Zardalu, Banganpali, Taimuria, Saleh Bhai, Badia Muna Syed, Intikhab, Anmole, Bombay Alphanso, Ghulab Khas, Pan, Lahotia, Kachnaliwala, and Jo villagey by applying seventy SSR markers, data collected on genetic diversity estimation bifurcated the varieties into three clusters. cluster 1, enclosed three varieties namely Bombay Alphonso, Intikhab, and Anmole together in genetic resemblance. Similarly, the cluster 2 assembled seven varieties i.e. Jo Village, Taimuria, Zardalu, Bagan Palli, Saleh Bhai, Badia and Munna Syed, making it the larger cluster. Lastly, the genetic similarity of the remaining four varieties such as Pan, Ghulab Khas, Lahotia, and Kachnalwala was found in close proximity. The current study singled out three unique fingerprints amongst the seventy SSRs applied. Baganpali cultivar contained unique fingerprints against primer MiKVR_a010; Gulab khas cultivar showcased unique characters against primer MiKVR_a052 and another distinguished fingerprint was observed in mango cv Baganpali against primerMiKVR_a109. It was an indication that these varieties possessed specific genotypic behavior against applied markers. It is concluded that these varieties can play a significant role in improving the genetic makeup of mango varieties and can divulge useful features for varietal selection in a breeding program.
Sequencing by Avidity Enables High Accuracy With Low Reagent Consumption
Authors: Arslan Sinan , Kellinger Matthew , Kruglyak Semyon , LeVieux Jake , Mah Adeline , Wang Haosen , Zhao Junhua , Zhou Chunhong , Bailey John , Byrne Matthew , Chang Chiting , Chen Steve , Dennler Claudia , Dennler Samantha , Dien Vivian , Fuller Derek , Garcia Francisco , Guo Minghao , Kelley Ryan , Khandan Omid , Klein Michael , Kim Michael , Lin Bill , Liu Yu , Lopez Tyler , Mains Peter , Price Andrew , Taylor Hermes , Tippana Ramreddy , Tomaney Austin , Zhang Richard , Abtahi Minna , Ambroso Mark , Bajari Rosi , Bellizi Ava , Benitez Chris , Berard Daniel , Berti Lorenzo , Blease Kelly , Blum Angela , Boddicker Andrew , Bondar Leo , Bui Chris , Cappa Kevin , Chan Joshua , Chang Victor , Charov Katia , Chen Xiyi , Constandse Rodger , Damron Weston , Dawood Mariam , Debruno Nicole , Dmalanta John , Edoli Laure , Elango Keerthi , Faustino Nikka , Feng Chao , Ferrari Matthew , Frankie Kieth , Fries Adam , Galloway Anne , Gavrila Vlad , Gemmen Gregory , Ghadiali James , Goddard Logan , Roginski Adriana , Hendricks Garren , Hentschel Jendrick , Hseih Doris , Hwang-fu Yu-Hsein , Im Scott , Jin Chaoyi , Kincade Daniel , Lajooie Bryan , Levy Shawn , Li Yu , Liang Vincent , Light William , Lipsher Jonathan , Liu Tsungli , Long Guixia , Ma Rui , Mailloux Jack , Mandla Kyle , Martinez Anyssa , Mass Max , Meron Michael , Moh Celyne , Moore Rachel , Moreno Juan , Neysmith Jordan , Niman Cassandra , Nunez Jesus , Ojeda Micah , Owens Jenna , Ortiz Sara Espinosa , Piland Geoffrey , Chen Steve , Proctor Dan , Purba Josua , Ray Michael , Rong Daisong , Saade Virginia , Saha Sanchari , Sirajudeen Luqmanal , Stengel Gudrun , Stinson Ryan , Stone Michael , Sundseth Keoni , Thai Eileen , Thompson Connor , Tomas Gustav Santo , Trejo Christy , Trieger Greg , Truong Diane , Tse Ben , Voiles Benjamin , Vuong Henry , Wong Jennifer , Wu Chiung-Ting , Yu Hua , Yu Ming , Zhang Cindy , Zhao Da , Zheng Frank , He Molly , Previte Michael
Published: November 2022

We present a novel sequencing chemistry implemented as part of the AVITI system. Relying on the proximal DNA binding sites created through DNA amplification on a solid support, avidity sequencing uses multivalent nucleotide ligands on dye-labeled cores to simultaneously form polymerase-polymer nucleotide complexes bound to clonal copies of DNA targets. These polymer-nucleotide substrates, termed avidites, decrease the required concentration of reporting nucleotides by 100x and yield a negligible dissociation rate. We demonstrate the use of avidites within a novel sequencing technology that surpasses Q40 accuracy and enables a diversity of applications that include single cell RNA-seq and whole human genome sequencing.
A Review of the Effectiveness of the Integrated Solid Waste Management System in Institutional Solid Waste Management in Zimbabwe
Authors: SHABANI TAKUNDA , JERIE STEVEN
Published: November 2022

Abstract
The review focuses on the effectiveness of the integrated institutional solid waste management system in Zimbabwe, utilising already published literature. Zimbabwean institutional solid waste is produced from schools, tertiary learning institutions, barracks, prisons, police camps and medical facilities. Institutional solid waste consist of plastics, papers, metals, textiles, rubber, food waste, glass and wood. Construction and demolition waste such as broken bricks, concrete, sand, stones are also produced from institutions. Medical institutions are sources of sharps, pathological, infectious, pharmaceutical, radioactive and cytotoxic solid waste. Institutions also discard electric and electronic waste such as computers and cell phones. Institutional solid waste management approaches in Zimbabwe are characterised by illegal dumping, co-storage of waste, inefficiency collection and transportation as well as co-disposal in poorly constructed landfills, open pits and incinerators. However, open combustion and burying of solid waste is done at onsite to minimise environmental eyesore. These strategies cause water, land and air pollution while flora and fauna are not spared. People are affected by gastrointestinal diseases, work related risks and psychological problems. These problems are fuelled by management approaches and legal framework which neglect integrated institutional solid waste management. However, integrated approach have potential to reduce environmental health problems, accelerate economic development and support social life of Zimbabweans. Therefore, integrated model which consist of various stages and processes of institutional solid waste management, numerous aspects and all stakeholders was developed.