bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigations on Three-phase Grid-Connected Inverter using PWM Controllers
Authors: Swamy D. Manikanta , Venkatesan M. , Subbarao M.
Published: November 2020

In recent years, a Multilevel Inverter (MLI) topology is highly preferred in the various renewable energy applications for converting power due to their merits. In this paper, a three-phase inverter has been designed for grid-connected applications using Proportional Integral (PI) current controller scheme. To generate a sequence, the Level shift (LS) and Phase Shift (PS) Pulse Width Modulation (PWM) methodologies are adapted. This topology has been designed with two stages: the DC-DC conversion stage and DC-AC conversion stage. The DC-DC conversion stage is used to enrich input DC voltage which is obtained from the solar PV array. The PI current controller has been designed to regulate the grid current with park transformation. The performances of the inverter have been examined in terms of Total Harmonic Distortion (THD) using different PWM techniques and also investigated with existing research works. The developed results are verified using MATLAB/ Simulink.
Oedipus-Inspired Pintos: The Plague of Prisons in Two Chicano Takes on the Prototypical Myth of Crisis
Authors:   National and Kapodistrian University of Athens, Greece, Delikonstantinidou Aikaterini
Published: November 2020

This article discusses two revisions of the tragic myth of Oedipus in the light of recent studies on the American prison crisis. In 2010, Luis Alfaro’s “Oedipus el Rey,” a play that draws on Sophocles’ Oedipus Tyrannus, addressed the national prison crisis which has encroached on barrio life with dreadful repercussions. One year later, Ernest Drucker employed the term “plague of prisons” to describe the phenomenon of mass incarceration in the US and shed light on its effects on poor communities of color, such as barrio communities. As if responding to Drucker’s study and Alfaro’s play, Law Chavez’s “Señora de la Pinta,” presented in 2012, gets its inspiration from the myth of Oedipus to dramatize US prison experience as a plague threatening the self and the barrio. The two plays are examined for what they reveal about the impact of the prison crisis on Chicano barrio life and Chicanidad.
Mestizaje and Intercultural Communication as the Analeptics to the Transhistorical Borderland Crises in Alejandro Morales’s Novel The Rag Doll Plagues (1992)
Authors:   Aristotle University of Thessaloniki, Greece, Toliou Foteini
Published: November 2020

This article focuses on Alejandro Morales’s novel The Rag Doll Plagues (1992) and explores the transhistorical dimensions of the subordination indigenous and mestiza/o identities experience against colonial and postcolonial authoritarian forces in the borderlands between Mexico and the United States. Spanish colonialism, US racism and eco-destruction, each transpiring in different moments of the New World history, are the diverse forms the borderland crises take up in the three Books comprising the novel. Mestizaje and intercultural communication, as well as the retrieval of the indigenous and Mexican cultural traditions, foster the ongoing creation of new hybrid racial, ethnic and cultural identities in all the three Books and, thus, emerge as the analeptics to the diachronically persistent plight of racism.
Risk Factors Predicting the Necessity of Renal Ultrasound in the Emergency Department
Authors: Merhav Goni , Razi Nira
Published: November 2020

Objectives:

Renal ultrasound (US) is widely used for diagnosing renal pathologies, though few of them, such as obstructive uropathy, require emergent urological intervention. During on-call hours, when medical staff is limited, it is important to prioritize which renal US examinations will be done. The aim of this study was to evaluate patient risk factors to predict the necessity of emergent renal US in the emergency department (ED).

Material and Methods:

All adult patients referred for renal US from the ED, during on-call hours from May 2015 to April 2017, were retrospectively included. The mean age was 64 years (18–98). Data were collected from the patients’ medical records. Urological intervention performed within the first 24 h following the US examination was recorded. Multivariate analysis was performed.

Results:

About 66% of the patients did not have a permanent urethral catheter, history of renal stones, or known abdominal or pelvic mass. None of these patients required an urgent urological intervention. The receiver operating characteristic curve was calculated at 0.883, 95% CI (0.84–0.92).

Conclusion:

Using only three variables, we can greatly reduce the number of renal US examinations done at on-call hours allowing for prioritization of only the necessary examinations.
Primary anaplastic lymphoma kinase-negative anaplastic large cell lymphoma of cervical spine presenting with quadriplegia: A case report and literature review
Authors: Basu Garga , Anthony Michael L. , Bakliwal Anamika , Chattopadhyay Debranjani , Joshi Prashant P. , Arora Rajnish Kumar , Mittal Radhey Shyam , Nath Uttam Kumar
Published: November 2020

Background:

An anaplastic large cell lymphoma (ALCL) involving the cervical spine and leading to quadriplegia is very rare.

Case Description:

A 48-year-old immunocompetent male presented with quadriplegia that warranted an anterior cervical corpectomy/fusion. He was previously being presumptively treated for cervical disease attributed to tuberculosis. The histopathology and immunohistochemistry revealed an ALCL that was anaplastic lymphoma kinase (ALK) negative. The patient had a favorable response to surgery followed by CHOEP (cyclophosphamide, doxorubicin, vincristine, etoposide, and prednisolone) chemotherapy.

Conclusion:

ALK-negative ALCL presenting with quadriplegia due to primary involvement of cervical spine is extremely rare, but must be diagnosed and appropriately managed.
Residential and farm buildings of the 14 – first half of the 17 centuries Rivne citizens according to the materials of archeological researches of 2007-2010
Authors: Chekurkov Vasyl
Published: November 2020

Автор описує результати археологічних розкопок, які не лише виявили особливі риси житлової та господарської забудови пізньосередньовічного і ранньомодерного Рівного, а й дали важливий матеріал для подальшого вивчення топографії міста. В історії його забудови виділено три основні етапи, що датуються XIV-XV ст., кінцем XV-XVI ст. і кінцем XVI – першою половиною XVII ст.
CURRENT TRENDS OF INSURANCE MARKET IN UKRAINE
Authors:   Ukrainian State University of Railway Transport, Steshenko Olena , Boiko Oleksandra ,   Ukrainian State University of Railway Transport
Published: November 2020

The stage of political and economic instability in Ukraine significantly influence on development of both individual insurance companies and the insurance market as a whole. The decrease of the solvency level of the population and trust to insurers have led to a significant reduction in demand for insurance services in recent years. That is why today insurers has faced a difficult task to increase the range, volume and quality of insurance services, increase the level of capitalization and financial reliability of insurance companies, gaining trust of legal entities and individuals. Following these measures aimed at overcoming crisis trends, the local economy will be able to attract essential investment resources, strengthen the effectiveness of state supervision of insurance activities, create a structural basis for the development of various types of insurance. One of the important factors in activating the development of the insurance business can be an effectively built underwriting process of an individual insurance company. The application of such an approach will enable the profitability and financial stability of insurance companies due to a thorough analysis and selection of risks for acceptance into insurance. The article analyzes the current state of the insurance market in Ukraine and highlights its main prospects for development. The methodology of the study is to summarize and compare the data characterizing the various components of the insurance market. The authors identify the trends in the insurance market in Ukraine, assess the situation according to various criteria, identify factors in the development of the insurance business, as well as problematic aspects of the insurance industry. The study has showed that there is a high dependence of insurance in Ukraine on the current political and economic system, which led to the dominance of demand for certain insurance products. The development of the modern insurance market is associated with the need for state support, is to create conditions for adequate functioning of the insurance market.
ANALYSIS OF THE USE LEVEL OF SECONDARY ENERGY RESOURCES IN ENERGY SECTOR OF UKRAINE
Authors:   Institute of Engineering Thermophysics of NAS of Ukraine, Fialko Nataliia , Prokopov Viktor ,   Institute of Engineering Thermophysics of NAS of Ukraine, Sherenkovskii Julii ,   Institute of Engineering Thermophysics of NAS of Ukraine, Yevtushenko Artem ,   Institute of Engineering Thermophysics of NAS of Ukraine, Polozenko Nina ,   Institute of Engineering Thermophysics of NAS of Ukraine, Maletska Olha ,   Institute of Engineering Thermophysics of NAS of Ukraine, Kyniak Olga ,   Institute of Engineering Thermophysics of NAS of Ukraine, Novakovskiy Maksim ,   Institute of Engineering Thermophysics of NAS of Ukraine, Dashkovska Irina ,   Institute of Engineering Thermophysics of NAS of Ukraine, Regragui Aboubakr ,   Institute of Engineering Thermophysics of NAS of Ukraine
Published: November 2020

The features of the use of heat and combustible and heat secondary energy resources (SER) in the energy sector of Ukraine are considered. The data on the use levels of various types of combustible SER, as well as high-potential heat SER by types of utilization plants are presented.
COMPETITION IN MASS MEDIA MARKET: FROM TV TO SOCIAL NETWORKS
Authors:   Taras Shevchenko National University of Kyiv, Shalman Tetiana
Published: November 2020

The importance of competition in mass media industry is constantly increasing, which results from globalization of information space, the growing number of media channels, network expansion and upgraded systems of information carriers. The article explores the notion of competition in the mass media sector as well as looks into the way competition influences the quality of media content. The research studies sectoral and cross-sectoral competition in media production, examines types of competition, ways of using competitive environment as effective resource in social communication. Attention is also paid to the peculiarities of influence exerted on the target audience by national and regional media channels. The author argues that regional local producers of mass media content cannot compete with national media channels, which limits the target audience’s scope of knowledge. The data show that competition influences content of an information product and encourages its producers to extend the system of information carriers, i.e. they start iversifying it by using social media, sites, YouTube channels in order to attract larger target audiences and advertisers.
FEATURES OF THE WORLD CONSUMPTION OF PRIMARY FUEL-ENERGY RESOURCES
Authors:   Institute of Engineering Thermophysics of NAS of Ukraine, Tymchenko Nikolay , Fialko Nataliia ,   Institute of Engineering Thermophysics of NAS of Ukraine
Published: November 2020

The article presents an analysis of the current state of the world consumption of primary traditional fuel-energy resources. The features of the consumption process in recent years in the world as a whole, in the EU and in Ukraine are considered. There is a fundamental difference in the dynamics of consumption of fossil fuels in the world as a whole and in the EU.
PECULIARITIES OF THE LEGAL STATUS OF A PUBLIC JOINT- STOCK COMPANY
Authors:   Yaroslav Mudryi National Law University, Tovkun Igor , Dubrova Hanna ,   Yaroslav Mudryi National Law University
Published: November 2020

We have considered the economic and legal situation of public joint stock companies in Ukraine. The analysis of the main features of a public joint - stock company as one of the most perfect legal mechanisms for the organization of the economy on the basis of combining the property of legal entities and individuals. In the course of performance of work historical features of emergence of such legal category as public joint-stock company were established. A study of the stages of enshrining the concept of "public joint stock company" in Ukrainian legislation during the existence of independent Ukraine, which was covered in a number of regulations, such as the Law of Ukraine "On Amendments to Certain Legislative Acts of Ukraine on Investor Protection", Law of Ukraine On Amendments to Certain Legislative Acts of Ukraine Concerning Simplification of Doing Business and Attracting Investments by Issuers of Securities ”, Law of Ukraine“On Management of State Property”, Law of Ukraine“ On Joint Stock Companies ”, etc. We have studied the relationships that arise directly during the activities of public companies. In particular, such relations apply to its governing bodies, which include: the general meeting as the highest governing body of the company, the supervisory board, which protects the rights of shareholders and regulates the executive body, and the executive body, which manages the current activities of the company. It is argued that public joint stock companies are subjects of the public sector of the economy, which in turn is the cause of a special process of activity, property regime, more stringent requirements for existence than private joint stock companies. The generalization of conclusions and information in the doctrinal literature related to this topic is made.
PROBLEMS OF EXHAUSTION OF THE EXCLUSIVE RIGHT TO EXPORT UNDER THE LEGISLATION OF UKRAINE
Authors:   Yaroslav Mudryi National Law University, Yevkov Andriy
Published: November 2020

The article examines the problems of normative establishment in the legislation of Ukraine of the exclusive right to export goods containing protected intellectual property objects, as well as the conditions and grounds for applying of legal norms enshrining the principle of exclusive intellectual property rights exhaustion to the exclusive right to export. Considering the limitation of the protection of exclusive rights to the territory of each individual state, the paper examines the problems of the territorial aspect (territorial models) of the exhaustion of rights, as well as the influence of exclusive rights to import, distribution and export on the implementation of international trade. The article notes that the right to export is directly established in the current domestic legislation of Ukraine only in respect of certain protected intellectual property objects, and substantiates the view that, given the inexhaustible list of property rights (ways of usage) for many other protected objects, the exclusive right of rightholders to export must also be recognized in respect of such objects. Concerning the implementation of export operations by the licensee the paper substantiates the point of view according to which, if in the license agreement the territory of validity of licensing rights is limited to the territory of Ukraine, then the licensee receives permission for distribution within the scope of this subjective right (i.e. within Ukraine) and, accordingly, is not entitled to export if there are no compelling reasons to consider such a prohibition as a way of restricting competition, abuse of right, etc. Regarding the export of goods by their purchasers after the first legal sale of such goods in a particular country, the paper notes that, despite the lack of direct instructions in the legislation, it can be assumed that the exclusive right to export should be exhausted after the first legal sale of goods containing protected objects, unless there are other grounds to believe that the export of such goods may further harm the rights and essential interests of the rightholder in the country where such initial introduction of goods into circulation took place (in the country of origin of the goods).
LEGAL REGULATION OF NATIONALIZATION
Authors:   State Organization “V. Mamutov Institute of Economic and Legal Research of the National Academy of Sciences of Ukraine”, Yatsenko Semyon
Published: November 2020

The article discusses the issues of latent and direct nationalization (eminent domain) in the Ukrainian economy, foreign use of nationalization, e.g. in the United States of America (USA), the French Republic, the Republic of Kazakhstan. In particular, the active participation of jurors in the nationalization procedure in the United States, examples of effective use of nationalization in the French Republic, and the comprehensive law of the Republic of Kazakhstan on state property. Theoretical and empirical basis for this study were the scientific definitions of nationalization, submitted to the Verkhovna Rada of Ukraine bills, current regulations, which indirectly indicate the forced transfer of ownership from a private entity to the state. The authorial definition of the concept of nationalization is offered, but in modern conditions of market economy and democratic political regime. Given the regulatory importance of nationalization (as well as privatization) for the economy, it is stated that before nationalization it is necessary to prepare a forecast of socio-economic consequences, and nationalization itself should be appropriate, adequate, effective, balanced, predictable, transparent and take into account public opinion, comply with the legal economic regime. The structure of legal relations on nationalization is considered: subjects, object, rights, and duties. The role of the employees and administration for positioning the business entity as an active participant and not a passive object of legal relations is considered. The possibility of applying other agreements during the nationalization of the business entity, except as a contract of sale, namely: rent and lifetime maintenance, are considered. Ways to improve the efficiency of resolving the issue of returning privatized enterprises to state ownership and the application of the institution of operational and economic sanctions in privatization agreements are proposed. The currently available ways to protect the rights and legitimate interests in the nationalization procedure are analyzed. E.g. it is proposed to extend the institution of property liability insurance to cases of expropriation, as currently nationalization and expropriation are classified by insurers as non-insured events.
SYSTEM OF ADMINISTRATIVE AND LEGAL MEANS OF OFFENSE PREVENTION IN THE FINANCIAL SPHERE
Authors:   National University «Lviv Polytechnic», Komarnytska Iryna
Published: November 2020

The article analyzes the system of administrative and legal means of crime prevention in the financial sphere in Ukraine. It is noted that in general the prevention of offenses in the financial sphere is aimed at eliminating the possibility of harm to individual subjects of financial and legal relations and the financial system of Ukraine, the state, society as a whole, eliminating the negative impact on the financial sector. Ukraine. It was found that the administrative and legal means of crime prevention in the financial sphere is a system of substantial and activity legal phenomena, through which the subjects of financial control, law enforcement and other bodies, citizens, their associations and other subjects of counteraction to financial offenses nature, establish the causes and conditions of misconduct in the financial sector, neutralize the factors that determine the delinquent behavior, have a preventive effect to prevent tax, budget offenses, banking offenses, financial offenses in the customs sphere and other financial offenses. The analysis of means of counteraction to torts which pose a threat to financial stability, security of the state, guarantee of financial rights of individuals and legal entities is presented. The specifics of the legal nature and legal features of the system of administrative and legal means of crime prevention in the financial sphere in Ukraine, the regulatory framework for their application, elements, varieties are detailed. The need to take into account the factors that determine tortious behavior of a financial nature is emphasized. It is emphasized that on the way of implementation of modern reforms in the financial sphere the legislator must form a legal basis for the implementation of financial and legal means of prevention of financial delinquent behavior, take into account the systemic nature of such means and the need for comprehensive consideration and standardization.
MECHANISM OF IMPLEMENTATION OF ADAPTIVE TRAINING IN TRAINING OF PUBLIC ADMINISTRATION SPECIALISTS
Authors:   Shupyk National Medical Academy of Postgraduate Education, Koshova Svitlana
Published: November 2020

In the article on the essence of the mechanism of introduction of adaptive learning in the training of public administration specialists, the author focused on the study of such legal categories as "mechanism", "adaptation", "social adaptation", "pedagogical adaptation", "adaptive learning" and directly on the concept "Adaptive training of public administration specialists". It is substantiated that the adaptive training of public administration specialists must be professionally oriented in public administration and related disciplines. Also, a student studying to become a public administration specialist must be clearly aware of his / her professional significance and obligation to perform the tasks assigned to him / her in an interactive form. A feature of adaptive training of public administration specialists is self-organization, self- management of students during the process of interactive learning. The professional activity of the teacher is inextricably linked with the educational activity of the student, as a result of which self-analysis, self-assessment, own development, self-realization and self-adaptation take place. The author proposes his own determinant of "adaptive training of public administration specialists" as an extensive process of training public administration specialists, which is aimed at transforming direct management skills and which occurs through the use of information and didactic support formulated in accordance with personal qualities of public students.management, in order to achieve effective learning. Also, in the article the author formulates a "mechanism" as a set of appropriate methods, tools, techniques and methods by which to achieve the objectives and goals.
INTERACTION WITH THE PUBLIC DURING IMPLEMENTATION OF THE SOCIAL PURPOSE OF AUTHORITIES
Authors:   Poltava State Agrarian Academy, Serdiuk Olha , Sytnyk Anatolii ,   Poltava State Agrarian Academy, Pavlushenko Olena ,   Poltava State Agrarian Academy
Published: November 2020

The article summarizes the theoretical foundations of interaction of local authorities with the public. The prerequisites for building effective interaction between local authorities and the public have been clarified. According to the Constitution of Ukraine the rights of citizens to participate in the management of state affairs are defined. The essence of the concepts is substantiated: interaction, interaction of local self-government bodies with the public, public organizations, public council. The main features of interaction. The types of interaction with the public of the Verkhovna Rada of Ukraine and the Cabinet of Ministers of Ukraine have been identified and substantiated, functions of interaction of local authorities with the public are outlined. The most common forms of interaction of local governments with the public in the implementation of its social purpose: meetings of citizens, local initiatives, participation in public organizations, involvement in the decision-making process of self-organization of the population. An analysis of the activities of public organizations in Ukraine and Poltava region, which showed a significant decrease in Ukraine and increase in Poltava region. The volumes and sources of financing of public organizations are determined. Foreground areas of interaction of local authorities with the public have been formed, including: access to public information and satisfaction of citizens' requests for information, electronic voting, consultations, consideration of appeals,consideration of proposals of public councils. Expected results: increase of openness of activity of authorities, increase of level of transparency of process of their decision-making, strengthening of socially useful activity of territorial community.
NATIONAL EXPERIENCE OF CREATION OF SITUATIONAL CENTERS IN PUBLIC AUTHORITIES
Authors:   The National Defense University of Ukraine named after Ivan Cherniakhovskyi, Hudyma Oleh
Published: November 2020

Today's realities place strict demands on society and public authorities to increase the efficiency of state management in the field of national security and defense. One of the ways to improve the quality of management decisions is to involve in the system of public administration additional special organizational and technical complexes - situational centers. Before starting any work, it is advisable to study the experience of leading countries and national developments in this area. The article considers the national experience (in the period from 1962 to the present) on the creation of situational centers (crisis centers, information and analytical centers) and systems of scientific and mathematical support of their activities for the needs of individual enterprises, state executive bodies, legislature, and namely: the automated control system of the enterprise "Lviv", the system of operational display of flights of space objects "Rytm-2", creation of a situation room for the Ministry of Justice of the USSR, the situational center in the operational headquarters for the elimination of the consequences of the Chernobyl disaster, information management system for the eliminate the consequences of the earthquake in Armenia, the situation hall of the Verkhovna Rada of Ukraine (“Rada-1”, “Rada-2”, “Rada-3” systems), the situation center under the President of Ukraine, the situation center of the Ministry of Defense of Ukraine, the information-analytical (situational) center under the Cabinet Ministers of Ukraine, the Main Situational Center of Ukraine and the network of situational centers of central executive authorities. The list of the basic guiding documents of the state concerning construction of the corresponding situational centers, the basic executors of the carried-out works is covered. The main shortcomings in the creation of situational centers of the third class are formed, namely: elaboration of issues of forecasting the emergence of crisis situations and elaboration of options for action to prevent them are at an early stage; organizational-functional (organizational-staff) structures of situational centers are formed, as a rule, by an expert. Proposals for improving the construction of situational centers and the quality of management decisions in the field of national security and defense of Ukraine.
Unidades de flujo a partir del indicador de zona de flujo (FZI) considerando el modelo petrofísico para yacimientos sub-saturados
Authors: Flores Pozo Jeniffer , Iturralde Kure Sadi , Gutiérrez  Hinestroza Marllelis
Published: November 2020

En la industria petrolera se cumplen varios parámetros en diversas etapas para realizar exploraciones y explotaciones de un yacimiento petrolero. Esas etapas comprenden la ejecución de gran variedad de estudios técnicos, geológicos, petrofísicos además de realizar un estudio en la caracterización de yacimientos el mismo que se enfoca a obtener la información necesaria que conduzca a una explotación adecuada del mismo. El propósito es determinar las unidades de flujo a partir del Indicador de la Zona de Flujo (FZI) considerando el modelo petrofísico de un yacimiento sub-saturado de la cuenca del lago de Maracaibo-Venezuela con la técnica basada en una modificación de la ecuación de Kozeny- Carmen, dándole la importancia que merece a la petrofísica ya que esta define los parámetros necesarios para tener resultados favorables, de igual manera se hace la lectura de registros que juegan un papel fundamental para la investigación. Se seleccionaron propiedades del yacimiento sub-saturado para la elaboración del mismo, luego se estableció los parámetros del modelo petrofísico para conocer el tipo, calidad de roca, densidad de matriz de formación, parámetros de corte, la arena neta petrolífera, arena neta total, conocer el Petróleo Original En Sitio (POES) a través del método volumétrico y de balance de materia. Una vez obtenidos todos los puntos necesarios se puso en marcha un modelo matemático que establece las unidades de flujo a partir del indicador de zona, este se realiza en 2 pozos seleccionados los mismos que son: LL-0773, LL-0848 cada uno con sus profundidades estableciendo la capacidad de almacenamiento de hidrocarburo del yacimiento sub-saturado para su explotación y comercialización quedando como referencia para nuevos estudios que consideren todos los parámetros para llegar al objetivo principal.
El IoT aplicado a la Domótica
Authors: Amaya Fariño Luis Miguel , Tumbaco Reyes Alfredo , Roca Quirumbay Esther , Villón González Tanya , Mendoza Morán Bolívar , Reyes Quimís Ángela
Published: November 2020

El “Internet de las Cosas”  es una tecnología en la que cada dispositivo tiene un chip con el cual se puede comunicar hacia internet, la aparición de controladores electrónicos de tipo Open Source y el concepto DIY ”Did It yourself” (hágalo usted mismo) ha dado lugar a la aparición de tecnologías económicas como Arduino y Raspberry, con las que los usuarios pueden realizar su proyectos de domótica (Hogar Inteligente); en este artículo se explica cómo comunicarse con un servidor web vía http desde un Arduino NODEMCU.
Monitoreo de Brucella mellitensis en la población de cabras “Chuscas” de la provincia de Loja-Ecuador
Authors: Román Cárdenas Franklin Antonio , Uchuari-Pauta Melania , Aguirre-Riofrío Edgar
Published: November 2020

La Brucelosis es una enfermedad infecciosa producida por Brucella mellitensis, siendo la causa más importante de aborto en cabras. En la provincia de Loja, al sur del Ecuador, se encuentra la mayor población de caprinos del país, que también reporta la presencia de abortos; en razas de tipo especializado se han realizado trabajos aislados para determinar la presencia de esta bacteria, sin embargo, del nicho de animales criollos no se dispone de información sanitaria realizada, el presente estudio se realizó con el objetivo de monitorear si una de las causas de los abortos en la cabra chusca criolla es la B. mellitensis, se levantó información epidemiológica por tres meses registrándose el 66.5% de abortos en los animales muestreados, se realizó el diagnóstico de B. mellitensis por medio de técnica de reacción en cadena de la polimerasa PCR, amplificando un fragmento de 731 pb sin registrarse amplificación del fragmento de Brucella investigado.
NMR Metabolomics and Metabolic Pathways Analysis of Cassava Genotypes at Different Harvesting Times and Cooking Characteristics
Authors: Alves Filho Elenilson Godoy , Silva Lorena Mara Alexandre , Martins Robson M. , Oliveira Willyane J.D.J. , Soares Vidal Cristine , Alves de Oliveira Luciana , Brito Edy
Published: November 2020

Cassava is an important staple food for low income countries. However, its cooking characteristics are especially affected by genotype. In this study, two groups of genotypes, namely hard to cook (HTC) and easy to cook (ETC), harvested at different times (9 and 15 months) were evaluated by 1H NMR and chemometrics. Additionally, the lignin of these materials was studied by 1H-13C HSQC. The carbohydrates were the most important class of compounds to differentiate the cassava genotypes. The correlation of NMR with cooking time and starch content showed that the higher content of primary metabolites, mostly glucose, can be associated to longer cooking times and reduction of starch corroborating the metabolic pathways analysis. Furthermore, it was observed that the lignin from cell wall did not differentiate the cooking performance of the genotypes.
Scaffold Analysis of Ligands Exhibiting GPCR Signaling Bias
Authors: Sanchez Jason , KC Govinda , Franco Julian , sirimulla suman
Published: November 2020

Signaling bias is a feature of many G–protein coupled receptor (GPCR) modulating drugs with clinical implications. Whether it is therapeutically advantageous for a drug to be G Protein biased or β-Arrestin (β-Arr) biased, depends on the context of the signaling pathway. Here, we explored GPCR ligands that exhibit biased signaling to gain insights into scaffolds and pharmacophores that leads to bias. More specifically, we used BiasDB, a database containing information about GPCR biased ligands and all ligands which show a (β-Arr) / G protein bias or a G protein / β-Arr bias are considered for the study. Four machine learning models were trained on these ligands to classify them. The features which were most important for training the models were analyzed. Two of these features (number of secondary amines and number of aromatic amines) were more prevalent in β-Arr biased ligands. After training a Random Forest model on HierS scaffolds, we found five scaffolds which demonstrated G protein or β-Arr bias. We also conducted t-SNE clustering, observing correspondence between unsupervised and supervised machine learning methods. To increase the applicability of our work, we developed a web implementation of our models which can predict bias based on a user-provided SMILES patterns. Our web implementation is available at: drugdiscovery.utep.edu/biasnet.
Beating the Limitation of Energy Gap Law Utilizing Deep Red MR-TADF Emitter with Narrow Energy-Bandwidth
Authors: Zhang Yuewei , Zhang Dongdong , Huang Tianyu , Li Guomeng , Zhang Chen , Lu Yang , Liu Ziyang , Duan Lian
Published: November 2020

The development of high-performance deep red/near-infrared organic light-emitting diodes is hindered by strong non-radiative processes as governed by the energy gap law. Herein, a novel BN-containing skeleton featuring linear N-π-N and B-π-B structure is developed, establishing partial bonding/antibonding character on phenyl core for enhanced electronics coupling of para-positioned B atoms as well as N atoms to narrow energy gaps. Also, the remained MR effect on the peripheral skeleton to maintain the MR effect to minimize the bonding/ antibonding character and suppress vibrational coupling between S0 and S1, thereby fundamentally overcoming the luminescent boundary set by the energy gap law. The target molecules R-BN and R-TBN exhibited extremely high PLQYs of 100% with emission wavelengths at 666 and 686 nm, respectively. The narrow FWMHs of 38 nm observed also testify the effectiveness of vibronic suppression. The corresponding OLEDs afford record-high EQEs over 28% with emission wavelength over 664 nm.
Mikania Mikrantha Leaf Extract Mediated Biogenic Synthesis of Magnetic Iron Oxide Nanoparticles: Characterization and Its Antimicrobial Activity Study
Authors: Biswas Aayushi , Chhangte Vanlalveni , Lalfakzuala R. , Nath Soumitra , Rokhum Samuel Lalthazuala
Published: November 2020

With an aim to introduce a new highly potent antimicrobial nanoparticles using an environment-friendly route, he present work reports the green synthesis of iron oxide nanoparticles (Fe3O4NPs) utilizing Mikania mikrantha leaf extract and its application as efficient antimicrobial agent. The green Fe3O4NPs have been described by X-beam diffraction (XRD), Ultraviolet-Visible (UV-Vis) spectroscopy, Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and Fourier Transform-Infra Red (FT-IR) investigation. The TEM image shows the rhomboidal Fe3O4NPs with average mean sizes 20.27 nm. The FT-IR investigation proved Fe3O4NPs have been balanced out through the associations of steroids, terpenoids, flavonoids, phenyl propanoids, phenolic acids and proteins present in the leaf extract. The synthesized Fe3O4NPs shows a very high antibacterial and antifungal property against 5 bacterial strains such as Bacillus cereus, Acinetobacter johnsonii, Pseudomonas aeruginosa, Achromobacter spanius and Chromobacterium pseudoviolaceum strain, and 4 fungal strains (Aspergillus niger, Penicillium citirinum, Fusarium oxysporium, and Candida albicans). The green synthesized iron oxide nanoparticles can interfere metabolic activities of microorganisms which determine its antimicrobial properties and could bring a promising application in the fields of medicine.
Hypolipidemic activity of parts of Luffa aegiptiaca in poloxomer induced hyperlipidemia
Authors: Abhilash G  , Anil kumar A  , Raja Sheker K  , Naveen B
Published: November 2020

Cholesterol and lipids are the major class of metabolites that are used to store high energy in the form of fats in the body. They are often stored in specific places in the system and some times misplaced in the bloodstream and other areas leading to metabolic disorders. The elevation in their quantities in serum is often termed as Hyperlipidemia. It affects most the worlds population adversely and is the causative factor for many comorbidities. Usually, medicinal plants exhibit the activities which are mainly due to the chemical constituents in them that are mostly phenols and flavonols. The plant Luffa aegiptiaca was investigated for its hyperlipidemic activity in high-fat diet-induced diabetes method. The results showed hyperlipidemic activity by lowering the lipid levels in the serum Four parts of the plant Luffa aegiptiaca were investigated for the antihyperlipidemic activity by extracting them with ethanol. These were tested for the lipid reducing property in the rat models induced by poloxamer drug. There was a successful induction of the Hyperlipidemia in the animals. The extracts showed a significant activity int his model. Fruits and leaves showed the best activity compared to other parts.
Comparision of antiepileptic property of various parts of datura
Authors: Anil Kumar A  , Raja Sheker K  , Naveen B  , Abhilash G
Published: November 2020

Epilepsy is the most common of the neurological conditions that are widely affecting most of the population around the world. It is a condition on its own and a symptom of other neurological conditions too. It affects almost one per cent of the human population. Many synthetic drugs are produced to treat epilepsy effectively in various mechanisms. Few of them are Barbiturates like phenobarbitone and barbital sodium, hydantoin derivatives like Phenytoin, Sedatives and azepam derivatives like Diazepam etc. Many drugs treat epilepsy but are not devoid of side effects as discussed. So herbs are supporting the system of medicine to treat epilepsy but don't have side effects and adverse effects. There are a lot of herbs that are used to treat the disease on among them is Datura stromonium. In this work, the comparison between the antiepileptic property of the different parts of Datura was investigated, which included Flowers, Leaves, Stems and Fruits. The activity was investigated in electrical shock method to induce epilepsy. The brain enzymes were used as estimating parameters. Overall, the flowers showed very less activity compared to stems followed by fruits, and leaves of the plant Datura stramonium showed the highest activity.
Evaluation of antihyperlipidemic activity of polyherbal capsules
Authors: Soujanya H  , Purushothaman M  , Jagadeeshwari S  , Shiva Kumar K
Published: November 2020

Hypercholesterolemia is one of the dreadful conditions that coexist in almost all the heart and endocrine-related dysfunctions. Simply elevated cholesterol levels in the blood is termed as hypercholesterolemia. Hyperlipidemia is also a synonym term and used to define elevated lipid levels. It affects almost all human beings in the world currently because of the changes in the food and living habits of the people. Most works proved those chemical constituents are antioxidants that demonstrate that the assertion that the oxidation is the main problem in causing the hyperlipidemia. So, in this research, antioxidant herbs like Psidium guava, Tephrosia and Moringa are used to prepare a gel that targets the fat deposits it the body and investigate for the antihyperlipidemic property. Herbal microspheres were prepared using the extracts of Tephrosia, Moringa and Psidium, which are incorporated into the sodium alginate and calcium carbonate. These microspheres were tested for their hyperlipidemic activity along with the extracts as such, and the results showed the microspheres showing better activity compared to the extracts compared to the standard drug atorvastatin.
Comparison of anti-acne property of carbopol gels
Authors: Shiva Kumar K  , Jagadeeshwari S  , Soujanya H  , Purushothaman M
Published: November 2020

Skin is the body is the largest organ and is the protective covering of the body. It is responsible for the normal functions like protection of the organs, healthy maintenance of the body and shaping and stretching. The skin is exposed to various types of stress like allergy-causing agents, disease-causing microorganisms etc. Medicinal plants are valuable resources that are known to the man from many generations that promote beauty and health. They are called as cosmeceuticals. These have various chemical constituents that promote beauty by reducing the acnes and killing the bacteria that causes and grow in the acnes. Anti-acne gels were prepared using the ethanol extracts of the plant Tulsi and Need incorporating the tea tree oil as a standard antioxidant. These were prepared, and the pH of the formulations was almost neutral to the skin and are stable in a stress test too. The anti-bacterial property of the gels was investigated in two methods, disc diffusion and turbidity method. The results showed a better activity of the formulations compared with tulsi and the standard antibiotic drug.
PUBLIC DISCOURSE AND THE GLOBAL PANDEMIC CHALLENGE
Authors: Бушев Александр Борисович
Published: November 2020

В статье обсуждаются изменения в языке и дискурсе, вызванные глобальным вызовом коронавирусной пандемии. Обсуждается современный медийный дискурс, в полной мере отражающий всю палитру общественных дискурсов. Рассматриваемые изменения характеризуются разноуровневостью - лексические, семантические, синтаксические, концептуальные, коммуникативно-риторические. В работе выделены стратегии антикризисной коммуникации, проявившиеся в медийной сфере в 2020 году.

The paper discusses the changes in the language and public media discourse caused by coronavirus pandemic. The new media discourse reflects the whole spectrum of public institutionalized and informal discourses. The results tend to elicit lexical, semantic, syntactic, conceptual and rhetorical and communicative changes. The paper singles out strategies and tactics of anti-crisis media communication during the outbreak of coronavirus infection in 2020.
CROP AREA MAPPING BY INTELLIGENT PIXEL INFORMATION INFERRED USING 250M MODIS VEGETATION TIMESERIES IN TRANSBOUNDARY INDUS BASIN
Authors: Khan Muhammad Mohsin , Masud Cheema Muhammad Jehanzeb , Mahmood Talha , Hussain Saddam , Waqas Muhammad Sohail , Nauman Hafiz Muhammad , Nawaz Mohsin , Saifullah Muhammad
Published: November 2020

Irrigation water could be managed properly by mapping area of various crops. Remote sensing data can provide useful Land Use Land Cover (LULC) for assessment of different crop area and change detection. The present study was carried out with core objective to map crop area within the Indus Basin’s transboundary. Four major crops (i.e. wheat, rice, cotton and sugarcane) were identified using Normalize Difference Vegetation Index (NDVI) time series that was picked up from MODIS sensors aboard Terra (EOS AM) and Aqua (EOS PM) satellites with 250m pixel resolution. Crop phonological information was used to train each pixel intelligently for interpretation of unanalyzed NDVI data into crops. Eight days of time series data was used for identification and mapping of various crops on the basis of their phenology for the years 2008, 2010 and 2013. Error matrix was prepared to reveal mapping accurateness and ground truthing was also done in particular canal commands within the Indus basin. Furthermore, the temporal variation in cropped area was determined and for accuracy check, secondary data was matched with prepared maps. LULC maps for year 2008, 2010 and 2013 were defined for Rabi and kharif seasons.
ASSESSMENT OF SEDIMENT YIELD USING SWAT MODEL: CASE STUDY OF KEBIR WATERSHED, NORTHEAST OF ALGERIA
Authors: Khanchoul Kamel , Amamra Amina , Saaidia Bachir
Published: November 2020

Erosion is identified as one of the most significant threats to land in increasing rates of soil loss and reservoir sedimentation. An integrated approach therefore requires sediment assessment for identification of its sources for efficient watershed management. The present study is aimed to examine the spatial and temporal sediment yield distribution potential and to identify the critical erosion prone zones within Kebir watershed, Algeria using Soil and Water Assessment Tool interfaced in GIS for the period from 1982 to 2014. The model is calibrated by adjusting sensitive parameters and validation is done using observed data from 1982 to 1998. The model performance checked by the coefficient of determination (0.76), Nash–Sutcliffe coefficient (0.75) and relative error (+8.19%) suggests that the model has performed satisfactorily for sediment yield prediction. The simulated outputs of the model show that the 33-year period of sediment load production is estimated to be 19.24×106 tons and a mean annual sediment yield of 856.14 T/km²/yr. Temporally, sixty-four percent (50%) of sediment yield generated in the watershed occurs in five months of the winter and fall seasons. The most erosion vulnerable sub-basins that could have a significant impact on the sediment yield of the reservoirs are identified. Based on this, sub-basin 16, 14, 13, 11 and 8 are found to be the most erosion sensitive areas that could have a significant contribution, of 50%, to the increment of sediment yield. Best management practices are highly recommended for the land sustainability because of the high sediment supply to the dams.
A REVIEW ON TECHNIQUES FOR WATER QUALITY MONITORING USING IOT DEVICES
Authors: Javaid Ali , Sajid Ahthasham , Zafar Afia , Ahemed Zaheer
Published: November 2020

In this paper is discussed the different kinds of environment monitoring systems related to water goodness. Different parameters are discussed to elaborate each water monitoring system with different aspects. The technology aspects of different approach techniques related to water quality monitoring with their way of implementation with the IOT aspect has been evaluated of past four years. In this paper, the workflow of different approaches of the technologies exploited will be discussed critically and also that which approaches focused on what parameters.
NARRATIVE PERSPECTIVES IN THE HEART IS A LONELY HUNTER BY CARSON MCCULLERS
Authors: Zhang Duan
Published: November 2020

Spiritual isolation and loneliness have always been the main topic of the works of the southern American writer Carson McCullers. Her superb literary creation lies in that, she not only integrates the theme of loneliness between lines of her works, but also strongly echoes and deepens that theme by use of brilliant narrative skills. The Heart is a Lonely Hunter is such a masterpiece on loneliness, decorated and permeated with exquisite narrative strategy. By means of the narrative theories of Gérard Genette and Shen Dan, and with NARRATIVE PERSPECTIVE as the starting point, the present paper tries to study the unique narrative strategy framed within this work. This paper points out that, McCullers’ portray of characters from many aspects, and her narration from multiple perspectives in this work, not only greatly exalt the work’s narrative tension and aesthetic effect, but also deeply reflect the internal perplexity and solitary state of mind of those people living in American South after the Civil War.