bluuebunny/crossref_metadata_2025 huggingface dataset:
CHRISTIAN BURIAL GROUND IN THE VILLAGE OF KHUNZAKH (BASED ON THE MATERIALS OF THE DAGESTAN-GEORGIAN JOINT ARCHAEOLOGICAL EXPEDITION)
Authors: Gambashidze Givi G. , Abiev Askerkhan K.
Published: July 2020

The article introduces the materials of the archaeological excavations of the Dagestan-Georgian archaeological joint expedition on the identified Khunzakh burial ground in 1978-1979, located in the villages. Khunzakh, on the Khunzakh plateau (Republic of Dagestan). The hunzakh plateau is the Central part of the medieval state formations of Sarir and then the Avar Kingdom, which were the most important Christian centers of the Eastern Caucasus in the IX-XIII centuries.As a result of the work carried out, 11 burials were identified, Dating from the IX-XV centuries. All burials were covered with a cultural layer containing archaeological material of the XI-XIII centuries. The identified burials represent three types of funerary structures: 1) an elongated pit of sub-rectangular shape with rounded corners or elongated-oval shape; 2) elongated sub-rectangular pits, slightly tapering to the end North-Eastern wall (in the "legs"), with ledges-shoulders along the side longitudinal walls and with a sketch of their small stones above the pit; 3) elongated sub-rectangular pits, slightly tapering to the end North-Eastern wall (in the "legs"), with ledges-hangers around the perimeter of the pit. Ledges-hangers, obviously, were used for installation of overlappings from stone slabs or wooden planks. The funeral rite is generally monotonous and is characterized by the placement of corpses in elongated pits carved into the rock, with orientation along the Central axis along the line SVV-SWZ, with the position of the deceased stretched out on his back, head in the Western sector, more precisely on the SWZ, the absence of burial equipment. The main features of the funeral rite and Dating of the burial ground allow us to refer it to the number of early Christian monuments of Sarir and consider it as a monument reflecting the process of Christianization of the population of medieval Hunzakh.
Variation in yield components and bioactive contents of black cumin seeds (Nigella sativa L.) with application of animal manures in ultisol lowland of Bengkulu
Authors: Herlina Herlina , Andriani Evi
Published: July 2020

Black cumin (Nigella sativa L) is known as herbal medicine that grows in subtropical regions and spreads from Asia to Europe. Plant parts that are used are seeds that contain bioactive compounds such as thymoquinone and thymol.  Information about the growth and production from Indonesia is still limited. Therefore it is necessary to develop efforts to cultivate black cumin in Indonesia, especially in sub-optimal land as initial information in the field of plant adaptation studies. This study aimed to determine the effect of manure on yield components and bioactive content of black cumin in the ultisol lowland of Bengkulu. The study was conducted at Dehasen Bengkulu University research station at an altitude below 100 m above sea level. The accessions of India, Syria, and Kuwait were used at the main plot, whereas media for growing viz cow manure, chicken manure, and without manure as a subplot. The study was conducted in February 2019 using the Split Plot Design with three replications. Observations were made on the components of yields and bioactive levels of seeds. The results showed that the application of chicken manure increased the components of the yield of black cumin seed by parameter number of capsules per plant, number of seeds per capsule, and number of seeds per plant and tended to reduce the weight of 1000 seeds. An increasing level of thymoquinone in the cultivation of black cumin in ultisol lowland of Bengkulu was obtained in the cow manure application. The increased levels of seed thymoquinone were accompanied by decreased levels of thymol for all accession used.
Cartografia a rischio di malaria nel comune di Maxixe: Caso del quartiere Chambone
Authors: Chitata Joaquim Gome André , Dgedge Gustavo Sobrinho
Published: July 2020

Questo articolo si concentra sulla valutazione della spazializzazione del rischio di malaria, sulla base di dati provenienti da aree residenziali per tipo di siti di riproduzione nel quartiere di Chambone (Maxixe, Mozambico). Per l’operativizzazione degli obiettivi, abbiamo optato, oltre alla revisione bibliografica, per un approccio quali-quantitativo, per osservazioni e indagini accompagnate. I risultati rivelano che le aree ad alto rischio di malaria a Chambone sono l’estremo nord-est, il centro-est, il sud e l’entroterra centro-sud-occidentale. Queste aree ad alto rischio, secondo la riclassificazione data dalla densità del nocciolo, sono di maggiore concentrazione di siti di riproduzione e abitazioni. Data la diversità nel modello di distribuzione spaziale del rischio e nei fattori con fattori di condizionamento, tenendo conto del tipo di pianificazione per tutte le aree del quartiere Chambone, era possibile sviluppare piani adeguati agli interessi locali per modificare l’attuale modello spaziale di distribuzione del rischio di malaria.
Effects of Working Capital Management on Firm’s Profitability: A Study on the Firms Listed Under DSE in Bangladesh
Authors: Hossin Md. Shakhaowat , Begum Sohana
Published: July 2020

This paper investigates the relationship between working capital management and financial performance of Pharmaceuticals and Textile firms listed at the Dhaka Securities Exchange in Bangladesh. The data analysis was carried on ten Pharmaceuticals and Textile firms for a period of 2013 to 2017. Secondary Data was analyzed by applying Descriptive Statistics, Regression and Correlation analysis to findthe relationship of current ratio, inventory conversion period and average payment period with Return on Asset. The findings indicate that the Pharmaceuticals and Textile firms’ performance is influenced by the variables relating to working capital. There is a positive relationship between profitability and current ratioand Inventory Turnover period shows a negative relationship with profitability but Average payment period shows insignificant impact on profitability. The study concludes that there exists a relationship between working capital managementand financial performance of Pharmaceuticals and Textile firms in Bangladesh. The study recommends that for the Pharmaceuticals and Textile firms to remain profitable, they should employ working capital management practice that will help in making decisions about investment mix and policy, matching investment to objective, asset allocation for institution and balancing risk against profitability.
A Lacanian Reading of Orhan Pamuk᾽s The Black Book
Authors: Abshavi Mojgan , Moayedi Shahla
Published: July 2020

From long time ago up to now, and in the trend of the human’s thought development, question about identity and the essence of self has been always an attractive matter for thinking. Searching for a lost soul mate, that can be supposed as a reflection of ourselves has been a great challenge for human beings, as well. The present research focuses on a type of psychoanalytic criticism which is based on ideas developed by Jacques Lacan in regard to Orhan Pamuk’s The Black Book. Lacan as a psychologist with a post-structuralist viewpoint believes that the unconscious is structured like a language. He states that language, the signifying chain with a perpetual sliding of the signified under the signifier, never provides "ultimate meaning" or a "transcendental signified". Accordingly, this study represents a Lacanian reading of Orhan Pamuk᾽s The Black Book with emphasis on the main roles of the "other", and language in forming of the unconscious and individual identity. Galip, the protagonist of the novel, apparently is in search of his lost wife "Rüya". But in fact, following this lack, he starts his search for knowing himself through a chain of signifiers. However, this search does not lead him to reach to a complete ultimate meaning of his "self". His bewildered subject cannot anchor at a fix point of integrated and wholeness of the "self".
Composting and vermicomposting residues of açaí and babassu for sustainable agriculture in Amazon
Authors: Silva Adriana Lins , Araújo Rita De Cássia Costa , Rodrigues Marcos , Souza Áurea Izabel Aguiar Fonseca e , Cruz Wilton Pires da
Published: July 2020

Agroindustrial wastes in southeastern Amazon are abundant and there are policies encouraging proper disposal for such wastes for sustainable agriculture. In this study we compared the chemical parameters of composts resulting from composting and vermicomposting sheep manure added to agroindustrial wastes as a bulking agent. Piles of compost were created using sheep manure, fruit waste, and a bulking agent. The treatments consisted of compost piles of: Tc - sheep manure and fruit pulp; Ta - sheep manure, fruit pulp and triturated açaí seeds; Ts - sheep manure, fruit pulp and sawdust, and Tb - sheep manure, fruit pulp and babassu coconut residue. After 50 days, a fraction of the compost from each pile was transferred to vermireactors to compare processes. At the end of the experiment, samples were taken in triplicate from all treatments in both composting and vermicomposting units for chemical analysis. The assessed variables were daily temperature of compost piles and vermireators, C/N ratio, Volatile solids (VS), total kjeldahl nitrogen (TKN), total phosphorus (TP), total potassium (TK), calcium (Ca), magnesium (Mg), sulfur (S), iron (Fe), copper (Cu), zinc (Zn), manganese (Mn), boron (Bo). Sawdust-based and babassu-based compost, from composting process, has the lower time for stabilization (about 40 days), pH closer to neutral and more efficient in reducing the C:N ratio than vermicomposts. Vermicomposting process increased the concentration of almost all nutrients in treatments, except for babassu-based compost.
Métodos de estimativa da evapotranspiração de referência para o município de Ibirubá, Rio Grande do Sul
Authors: Mantovanelli Bruno Campos , Chechi Leonardo , Magalhães Ticiana François , Petry Mirta Teresinha , Terra Lueni Gonçalves , Weiler Elenice Broetto , Londero Diego Dambrós , Martins Juliano Dalcin
Published: July 2020

O conhecimento preciso e a correta quantificação da evapotranspiração são essenciais para programas de irrigação e cálculo da demanda evaporativa da atmosfera. Objetiva-se com este trabalho comparar métodos de estimativa da evapotranspiração de referência para o município de Ibirubá-RS. Os dados utilizados correspondem às variáveis climatológicas no período de 1° de outubro de 2017 a 31 de maio de 2018. Estas informações são constituídas pelas séries horárias de temperatura média (Tmed), mínima (Tmin) e máxima (Tmax), umidade relativa média (URmed), mínima (URmin) e máxima (URmax), velocidade média dos ventos a 2 metros de altura (u2), temperatura média do ponto de orvalho (Td) e radiação solar incidente (K?). Os métodos de determinação da evapotranspiração de referência (ETo) utilizados no trabalho foram Penman-Monteith (FAO-56), Penman, Priestley & Taylor, Tanner & Pelton, Makkink, Jensen-Haise, Hargreaves-Samani, Camargo, Benevides-Lopes, Turc e Linacre. Para fins de comparação, adotou-se o método de Penman-Monteith como método padrão para a estimativa ETo, comparando-se a os valores obtidos pelos demais métodos. Foram realizadas análises estatísticas de regressão, correlação e multivariada como critério de sumarização dos dados. Os resultados expressos a partir da análise de correlação e dos componentes principais, evidenciaram de forma adequada os reais efeitos das variáveis climatológicas sobre os métodos de estimativa testados. O efeito da radiação solar (Q*) tem maior impacto sobre os métodos de estimativas de ETo.
Mantra Sasak: Klasifikasi, Fungsi, dan Penggunaannya oleh Masyarakat Desa Ganggelang
Authors: Fakihuddin Lalu , Sarwadi Gita
Published: July 2020

The purposes of this research are: (1) To classify the Sasak verbal-spells based on the variations of the language being used and the purpose of its implementation; and (2) to describe the function and its usage for the Sasak people in general and Ganggelang villagers, North Lombok in particular. This research uses a qualitative research method that both descriptive-interpretative. One of the reasons for choosing such a method is because it is compatible with the purpose of this research which is to document and describe the usage of Sasak verbal-spells. The data are collected by interviewing informants and gathering the results of the verbal-spells, its usage, and function by the Sasak people. To classify the data based on the language medium, a hermeneutic approach has been employed. The data analysis refers to perspective-constructivist model, that is directed by the intentions, categories that have been determined, and hypotheses that are aimed to be achieved. The result of this research, which is the verbal-spells then analyzed based on the language such as Arabic (verbal and written) spells, mixed between Sasak and Arabic spells, and Balinese spells or known as Puji Bali. Based on its purpose of implementation, Sasak verbal-spells are categorized into for healing purposes, Senggeger: a type of voodoo to attract the loved ones, Seasih-asih: to make one falls in love, supernatural power, and draining someone’s (physical) energy/power. Based on its function and practical usage, the Sasak verbal-spells have functions as healing/preventing diseases, to Seasih-asih purposes, to Senggeger/sencolet purposes, as a medium to ease childbirth processes, to counter other’s spells (sengkeles), and to counter possible dangers or destructions (sepenebeng/ajian kekebalan) and to drain someone’s energy.
ANALISIS KOHESI DAN KOHERENSI WACANA PADA LEMBAR KERJA SISWA BAHASA INDONESIA UNTUK SMA/MA/SMK/MAK KELAS XI
Authors: Aisyah Nur
Published: July 2020

Tujuan dari penelitian ini adalah ditemukannya aspek-aspek kohesi dan koherensi yang belum tepat pada wacana dalam Lembar Kerja Siswa (LKS) Bahasa Indonesia untuk SMA kelas XI kurikulum 2013 edisi revisi 2016 Penerbit Graha Printama Selaras tahun 2016. Adanya kedua unsur tersebut dapat menjaga kepaduan dari sebuah wacana sehingga ide yang disampaikan penulis akan secara tepat tersampaikan kepada pembaca. Metode penelitian yang digunakan dalam penelitian ini adalah metode deskriptif kualitatif. Sumber data yang dipilih dari lembar kerja siswa tersebut adalah berupa wacana yang terdapat pada lembar kerja siswa semester genap dan ganjil. Sebelum diketik pada komputer, peneliti mencatat semua data yang ditemukan pada sebuah kartu data. Kartu data berfungsi untuk mengingat dan mempermudah peneliti dalam mengelompokkan data-data yang sudah didapat untuk dianalisis kohesi dan koherensi yang terdapat di dalamnya.Teknik yang digunakan untuk melengkapi metode analisis dokumen adalah teknik catat. Metode simak dengan teknik simak bebas libat cakap tanpa tatap muka juga digunakan untuk mendapatkan informasi bahwa LKS tersebut memang banyak digunakan berbagai sekolah di Indonesia sebagai bahan ajar yang digunakan guru.

Hasil penelitian menunjukkan bahwa: (1) bentuk yang paling banyak digunakan adalah kohesi gramatikal dengan kategori konjungsi, yaitu dengan jumlah 15 data kesalahan yang ditemukan, seperti dan, namun, dengan dan tetapi.. Repetisi 5 data, sinonimi 3 data, referensi 1 data, dan ellipsis 3 data. (2) Kesalahan koherensi yang ditemukan dengan jumlah 8 data. Kesalahan piranti kohesi gramatikal, seperti referensi, substitusi, elipsis tidak banyak dijumpai pada wacana tersebut. Begitu juga piranti kohesi leksikal, seperti repetisi, sinonimi tidak banyak ditemukan dalam penelitian ini. (3) Kesalahan berbahasa lain yang sering ditemui, yaitu ketidaktepatan dalam penggunaan huruf kapital serta tanda baca sehingga menjadikan kalimat kurang efektif.
KEARIFAN LOKAL DALAM LIRIK LAGU MINAHASA “OPO’ WANA NATASE”
Authors: Ika Romika
Published: July 2020

Penelitian ini bertujuan memperkenalkan kearifan lokal di Minahasa melalui lirik lagu “Opo’ Wana natase”. Kearifan lokal yang diemban Lagu “Opo’ Wana natase” dapat dijadikan sebagai sarana pendidikan karakter dan pembelajaran bahasa daerah yang tak dapat dibelajarkan oleh mesin-mesin digital yang melanda Revolusi Industri 4.0. Revolusi 4.0 telah memandang teknologi informasi menjadi basis dalam kehidupan manusia. Penggunaan daya komputasi dan data yang tidak terbatas akibat perkembangan internet dan teknologi digital yang masif sebagai tulang punggung pergerakan dan konektivitas manusia dan mesin menyebabkan segala hal menjadi tanpa batas (borderless). Era ini telah  mendisrupsi berbagai aktivitas manusia, termasuk di dalamnya bidang ilmu pengetahuan, teknologi, dan humaniora, tanpa kecuali bidang pendidikan. Metode yang  digunakan adalah metode deskriptif dengan teknik simak, catat, dan analisis. Peneliti telah melakukan penelitian melalui model pembelajaran PAILKEM dan pembelajaran campuran (blended learning) pada siswa SMK Nusantara Tondano Minahasa. Hasil Penelitian menunjukkan bahwa Lirik lagu sebagai teks atau wacana dapat mencerminkan realitas kehidupan. Nilai-nilai tersebut diyakini kebenarannya dan menjadi acuan dalam bertingkah laku sehari-hari dengan masyarakat setempat. Lirik lagu yang berjudul “Opo’ Wana natase”, merupakan lagu pujian kepada Tuhan /himne. Nilai-nilai budaya dalam lirik lagu ini mencakup: 1) kearifan lokal Minahasa yang dapat diangkat sebagai kearifan nasional (Pakatu’an Wo Pakalawiren, (berkatilah dengan umur panjang dan kesejahteraan) Si Toi Timou Tumou Tou, (manusia lahir untuk memanusiakan manusia lain). Nilai-nilai religi:Lagu “Opo’ Wana natase” bertemakan ketuhanan, karena lagu pujian orang-orang Minahasa ini menyiratkan keyakinan tentang adanya Tuhan Mahapencipta, Mahapengasih, dan Mahatahu akan segala sesuatu yang ada di dunia ini.3) Alam adalah sumber kehidupan manusia sebab itu hubungan manusia dengan manusia, manusia dengan alam, manusia dengan Tuhan,  harus dijaga agar manusia Minahasa khususnya, manusia universal pada umumnya dapat hidup makmur dan damai.
Analisis Kestabilan Lereng Berdasarkan Kekuatan Geser Massa Batuan Terhadap Perubahan Kandungan Air Pada Tambang Batubara Di Area Blok Menyango
Authors: Wardana Novandri Kusuma
Published: July 2020

Mining activities is commonly to work with the problem of stability of rock mass, then befordesaining mine’s slope should know rock shear strength parameters, such as cohesion (c) andinternal friction angle value ( . Beside those parameters, also needed to know the impact ofwater content to the rocks. The water content will effect rock’s shear strength, proof by the rockcondition which is ductile when it is dry and soft when it is wet. Based on test results was doneusing sandstone with laboratory scale of direct shear test were analyzed using mohr – coulomband patton criteria (1966). It is known that the cohesion (c) of sandstone decreased from 510,35kPa at natural condition down to 133,75 kPa at wet condition. The internal friction angle ( ) alsodecreased from 54,56° at natural condition down to 48,45° at wet condition. The reduction of theshear strength is caused by fragments and clay minerals characteristics which are so reactiveand very easy to absorb water so that the cohesion of the sandstone reduce the active normalstress so that working the shear stress required to cause the shear failure becomeweaker. From the results, it is also known that the shear surface roughness had a lot ofinfluence on the shear strength the normal stresses applied on the direct shear tests werevery low under 20% of UCS.
ANALYSIS OF THE TECHNICAL REQUIREMENTS FOR THE FIRE-FIGHTING DELIVERY HOSES USED TOGETHER WITH THE FIRE-RESCUE EQUIPMENT
Authors: Prisyajnyuk V. , Semychayevsky S. , Yakimenko M. , Osadchuk M. , Svirskiy V. , Milutin O.
Published: July 2020

The urgency of the issue of substantiation of technical requirements to fire-fighting layflat delivery hoses for fire-rescue equipment is given.
Fire hoses are a significant component of fire fighting equipment. According to DSTU 2273, a fire hose is a flexible conduit fitted at the ends with connecting heads intended for the transport of extinguishing agents.
Among the technical means intended for the transportation of extinguishing agents to the fire cell, the main role is certainly played by delivery fire hoses. According to DSTU 2273 delivery fire hoses (in EU countries they are classified as "layflat") are intended for transportation of extinguishing agents under excess pressure.
At present, there are a number of standards in Ukraine and in the leading countries of the world that set the technical requirements for delivery fire hoses, in particular those used in conjunction with fire rescue equipment, namely DSTU 3810-98, DIN 14811, EN 14540: 2004 + A1: 2007, etc. In addition, a draft state standard is being developed in the Republic of Belarus.
Considering the process of gradual integration of Ukraine into the European Union and the fact that the requirements of the current national standard DSTU 3810-98 do not meet the modern European requirements for layflat delivery hoses for fire-fighting equipment, a pressing issue is the justification such types of hoses.
In order to assist in solving this problem, the Ukrainian Research Institute of Civil Protection is currently conducting a research work "Justification of fire hose test methods", within which a national standard will be developed, which regulates general technical requirements and test methods for the fire-fighting layflat hoses for fire – rescue vehicles.
The basic technical requirements for the specified hoses, which meet the modern requirements of the EU and which, after appropriate experimental justification, can be considered in the draft national standard, which regulates the general technical requirements and test methods for the fire-fighting layflat hoses for fire – rescue vehicles to be developed. This publication lists six tables that provide basic specifications for delivery fire hoses.
Keywords: abrasion, burst pressure, layflat delivery fire hoses, fire – rescue vehicles, proof pressure, technical requirements, specifications, working pressure.
In Search of the Missing Narrative
Authors: Devlin Julia
Published: July 2020

The trauma of forced migration is not only detrimental for the victims themselves, but can overcast subsequent generations as well. This article examines the role of the family narrative in the case of Polish deportees and their descendants. Drawing upon Aleida and Jan Assmann's concepts of communicative and cultural memory, I address how the development of self-construction and identity of the second generation was impeded by their parents' difficulties to verbalize a traumatic past. I argue that aside from the communicative memory, the cultural memory of this group was affected as well as their experiences of victimization were politically and socially not recognized.
Гендерні особливості агресивної поведінки в контексті психічного здоров’я старших школярів
Authors: Уханова Анастасія , Архипова Тетяна
Published: July 2020

У статті висвітлено результати дослідження агресивної поведінки в контексті психічного здоров’я старших школярів. Для участі в дослідженні взято групу підлітків 10-11 класів загальноосвітньої школи № 9 м. Подільськ. Обсяг вибірки склав 80 осіб: 40 дівчат та 40 юнаків. Вік респондентів: 15-16 років. Дослідження проводилося за допомогою трьох методик: методика самооцінки психічних станів за Г. Айзенком, методика дослідження агресивності А. Басса-А. Дарки та тест агресивності (опитувальник Л. Г. Почебут). Ми припустили, що агресивна поведінка респондентів чоловічої та жіночої статі може мати відмінності. Таким чином метою дослідження було визначити гендерні особливості агресивної поведінки в контексті психічного здоров’я старших школярів. Як показало дослідження, хлопчики частіше використовують фізичну агресію, а дівчата вербальну. Нами було виявлено статистично значущий зворотній зв’язок між рівнем фізичної і предметної агресії у хлопчиків старшого шкільного віку (r = - 0,388; p <0,01). В результаті аналізу взаємозв’язку між вербальною агресією та негативізмом у групі хлопчиків було встановлено прямо пропорційний статистично значущий зв’язок (r = 0,429; p < 0,01). Також прямо пропорційний зв’язок було встановлено між рівнем розвитку дратівливості і вербальної агресії (r = 0,550; p < 0,001) і між рівнем дратівливості і негативізмом респондентів чоловічої статі (r = 0,457; p < 0,01). Прямо пропорційний статистично значущий зв’язок в групі підлітків жіночої статі встановлено між ригідністю та агресивністю (r = 0,359; p < 0,05), а також між рівнем образи та агресивністю (r = 0,420; p < 0,01). Результати роботи можна використовувати, як джерело розширення фактологічної бази у вивченні феномена агресивної поведінки. Матеріали дослідження можуть бути використані для навчання майбутніх педагогів і психологів, а також для написання інших наукових робіт, які стосуються даної проблеми. Перспективами подальшого розвитку в цьому напрямі є вивчення взаємозв’язку агресивної поведінки з чинниками психічного здоров’я старших школярів.
Розвиток комунікативних компетенцій професіоналізму у майбутнього фахівця гуманітарного профілю
Authors: Лосієвська Ольга
Published: July 2020

У статті розглядаються теоретичні та практичні аспекти впровадження компетентнісного підходу в освіту, розкривається роль міжвузівської взаємодії в процесі розвитку комунікативних компетенцій майбутнього фахівця гуманітарного профілю. Наголошується, що розвиток вищої школи займає важливе місце в системі безперервної освіти, є значущою складовою частиною стратегії загальнонаціонального розвитку, оскільки повʼязаний з економікою, наукою, технологією і культурою суспільства в цілому. Підкреслюється, що одним з першочергових завдань, спрямованих на посилення ролі освіти в соціально-економічному розвитку, є приведення змісту освіти, технологій навчання і методів оцінки якості освіти у відповідність до вимог сучасного суспільства. Показано, що в цілях оптимізації навчання актуальним є застосування інноваційних освітніх технологій, а компетентнісний підхід дозволяє актуалізувати у майбутніх фахівців гуманітарного профілю попит на освіту і передбачає високу якість підготовки фахівців. На сучасному ринку праці успіх випускника-гуманітарія обумовлений не тільки грамотною підготовкою, а й мобілізацією внутрішніх сил, старанністю, ініціативністю, відповідальністю за свою роботу, прагнення до професійного зростання і розвитку. Конкурентоспроможним буде такий молодий фахівець гуманітарного профілю, який демонструє не тільки відмінні сучасні знання, а й інформаційно-технологічну готовність, знання засобів інформаційних технологій, вміння відбирати, оцінювати і використовувати інформацію, комунікативність і вміння працювати в команді, здатність до самоосвіти і потребу у поступовому підвищенні кваліфікації. У звʼязку з цим вдосконалення процесу підготовки майбутніх фахівців гуманітарного профіля багато в чому визначається впровадженням компетентнісного підходу у вищу освіту.
Speciﬁ c composition of microﬂ ora circulating at the FARM “Quant System” and its resistance to antibacterial medicines
Authors: Kisera Ya. , Bozhyk L. , Grynevych N. , Storchak Yu.
Published: July 2020

Accumulation of opportunistic pathogenic bacteria in the aquatic environment may lead to the changes in the structure of the surface cover microbiocenosis as well as the fish intestinal tract. In its turn, it causes the growth of pathological processes in the fish organism, reduces the barrier functions of tissues and mucus and, as a consequence, may induce the spread of bacterial infections. Thus, assessing the state of fish organism, it is necessary to take into account the analysis of the epizootic situation in water (i.e. presence of infectious and invasive diseases of fish, death of fish) as well as condition of the skin, gills and gastrointestinal tract. The results of bacteriological studies of washes from the skin, gills and intestines showed that in the conditions of farming among rainbow trout of different age groups, E. coli, low fermented E. coli, Enterobacter spp., Klebsiella pneumoniae, Staphylococcus spp., Flavibacterium spp., Enterococcus spp. and Citrobacter spp. For the purposes of determining the sensitivity of isolated cultures to antibacterial drugs, it was found that Enterobacteriaceae are sensitive to enrofloxacin, cotrimoxazole, doxacillin, chloramphenicol, gentamicin, ceftriaxone, cefoperazone, ceftazidime and cefpiromycin and resistant to oxytetracycline, amoxicillin and ampicillin sulbactam. E. coli also demonstrated resistance to amoxicillin and cefpirome and sensitivity to enrofloxacin, oxytetracycline, cotrimoxazole, doxacillin, chloramphenicol, ampicillin sulbactam, gentamicin, ceftriaxone, cefoperazone, ceftazidime. Klebsiella pneumoniae was resistant to enrofloxacin, amoxicillin and ampicillin sulbactam, while Flavobacteriaceae were resistant to amoxicillin and ampicillin sulbactam and sensitive to all other antibacterial drugs.
Key words: rainbow trout, microflora, skin, gills, intestines, antibacterial agents, resistance, sensitivity.
Identification of Salmonella spp and serovars Typhimurium, Enteritidis by qPCR
Authors: Rublenko N.
Published: July 2020

This article presents the results of the identification of the Salmonella genus as well as serovars Enteritidis and Typhimurium by a real-time polymerase chain reaction. We constructed three pairs of primers and fluorescent probes to simultaneously identify the Salmonella genus, serovars Enteritidis and Typhimurium in a qPCR. The specificity of the primers was evaluated on Salmonella strains of different serovars from the National Center for Strains of Microorganisms (UNCMS) strains of the State Scientific Control Institute of Biotechnology and Strains of Microorganisms (SSCIBSM) and 46 Salmonella strains isolated from poultry. E. coli ATCC 25922, Bacillus cereus ATCC 11778, Listeria monocytogenes ATCC 19112 from UNCMS collection were used to check the specificity of the primers as heterologous samples. Bacterial DNA was extracted using a DNA Sorb B (Amplisens) kit, and realtime PCR was accomplished with the "Real-time PCR kit" (Syntol) on Bio-rad CFX. A series of 10-fold S. Typhimurium and S. Enteritidis DNA dilutions were studied to evaluate the sensitivity of the primers: 10-1-10-5. The analytical sensitivity of primers for detection of the genus Salmonella is: for S. Typhimurium - 0.25 ng/sample (Typhimurium) and S. Enteritidis - 0.27 ng/ sample (Enteritidis). The results of the studies confirmed the specificity of the primer set and the high sensitivity. No hybridization of primers with DNA samples of other bacteria found, in particular, the nonspecific reaction products were absent. The primer sets for the detection of DNA of Enteritidis and Typhimurium serovars also has high specificity. If necessary, this set of primers can be used to perform a multiplex qPCR, that can simultaneously identify bacteria of the Salmonella genus and differentiate Enteritidis and Typhimurium serovars.
Keywords: Salmonella, bacteria, polymerasechainreaction, DNA, qPCR.
Hematopoiesis and biochemical proﬁ les of dogs' blood by chronic heart failure
Authors: Troﬁmjak R. , Slivinska L.
Published: July 2020

The present study was undertaken to evaluate if any signiﬁ cant hematological and biochemical changes occur in dogs with chronic heart failure (CHF), that will help in the diagnosis and prognosis of CHF. According to the obtained data, neutrophil leukocytosis was found in 22.2% of the animals in the experimental group, and anemia was found in 50.0%. Among them the 77,8 % of animals had nonregenerative anemia, the 77,8 % – hypochromic anemia, 38,9 % of – microcytic anemia. Neutrophil leukocytosis was registered in dogs with regenerative shift of the nucleus to the left (13.8%) and to the right (5.6%), and without changes in the leukogram (2.8%). It should be noted that 55.6% of animals with signs of CHF were also diagnosed with changes in the ratio of segmented neutrophils (degenerative shift of the nucleus to the left) in the absence of leukocytosis. Hypoproteinemia was found in 8,3% of animals, hypoalbuminemia in 13,8%, urea and creatinine concentrations were increased in 16,7 % and 19,4%, respectively. Hypocalcaemia was observed in 5,6% of dogs, inorganic phosphorus content was higher in 13,9%, slight hyponatremia was observed in 19,4%. The activity of enzymes in the serum of dogs in the experimental group ranged widely and was higher in ALT (p <0.001), AST (p <0.05), ALP (p <0.001), GGTP (p <0.01) compared with the control group.In the experimental group of 36 animals in 22,2 % of dogs were diagnosed cholestasis, in 22,2 % – hepatopathy, in 11,1 % – chronic kidney disease, and 8,3% –enteropathy, 5,5 % – paraneoplastic syndrome. Biochemical analysis of blood in dogs with signs of CHF is relevant, because it allows to diagnose comorbidities that may worsen the prognosis in these animals, and their timely detection and correction will increase the eﬀ ectiveness of treatment.
Key words: chronic heart failure, dog, hematology analysis, anemia, leukocytosis, hypoalbuminemia, renal failure,cholestasis, hepatopathy.
Сorrection of sodium and potassium content in the blood of the cows with the aid of feed additives of Hermatsins taking into account typological features of the nervous
Authors: Zhurenko E.
Published: July 2020

The eﬀ ectiveness of correction of the content of some macronutrients in the blood of cows with diﬀ erent types of higher nervous activity (HNA) and vegetative status has been conﬁ rmed using feed additive “Germatsink”. In cows with a weak type of higher nervous activity, the potassium content in the serum in 10 days after the administration of the nanopreparation increased by 16.0% (p <0.05), calcium by 4.7%. 10 days after the start of the task of the nanopreparation, the sodium content in the blood cells of the cows of HF and a weak type of GNI becomes less than only 8.7% (p <0.05) and 15.1% (p <0.05) compared with the cows with SVR type GNI.The sodium content in blood cells 30 days after the start of studies in cows of HF and a weak type of GNI does not signiﬁ cantly diﬀ er from the indicators of cows of the CBP type. However, 45 days after the Germatsink feed supplement was prescribed in the blood cells of cows of a weak type of GNI, the content of this metal again becomes signiﬁ cantly higher by 9.2% (p <0.05) of the cows of the SVR type of GNI.In cows with a weak type of higher nervous activity, the serum potassium content within 10 days after the start of the task nanopreparations increases by 16.0% (p <0.05). According to the inﬂ uence of the feed supplement Germacin in the blood cells of sympathetic cows, the ratio of sodium to potassium is normalized. It should be noted that the assignment of the Germacinc feed additive to animals with SVR, SVI and SN type of GNI does not signiﬁ cantly aﬀ ect the potassium transmembrane potential. Whereas the value of this index in cows with a weak type of HNA decreased by 20.9% in 45 days of research (p<0.001). Therefore, the studies shown that the administration of feed additive “Germatsink” to cows with diﬀ erent types of HNA had corrective eﬀ ect on the content of some macronutrients in the blood of animals.
Key words: nerve activity, cows, macronutrients, feed additive, blood cells.
Story in the Qur'an and Its Relevance in Early Childhood Education
Authors: Ali Imran Sinaga  , Afrahul Fadhilah Daulay  , Rosmawati Lubis
Published: July 2020

The purpose of this study is to find out: the disclosure of stories in the Qur'an, and the relevance of the stories in the Qur'an to early childhood education. The research method used is qualitative. Data collection techniques carried out by documentation and interviews. Data collection procedures are carried out with the stages of data collection, data reduction, data presentation, and drawing conclusions. Checking the validity of the data is carried out with four criteria, namely credibility, transferability, dependability, and confirmability. Research findings show the story in the Qur'an means the stories or news of the Qur'an about events or events that befell the people or previous people, both involving human nations and the nations of the jinn and angels, even nations of the animal group who acts like a human. The story in the Qur'an is the best story, it is a true story and contains a lot of "ibrah (lessons) for people who think deeply, so it must be thought of. The story in the Qur'an has very close relevance to Islamic education. Such a close relationship is marked by the existence of stories in the Qur'an as a model or form of Islamic education that is able to inspire the birth of several principles and theories of Islamic education.
Toxicologist`s opinion on the mechanisms of virus-induced hemoglobinopathies with toxic pneumonitis and systemic hypoxemia from COVID-19 and substantiation of rational detoxification methods
Authors: Prodanchuk M.G. , Balan G.M. , Kurdil N.V. , Zhminko P.G. , Bubalo N.M.
Published: July 2020

Coronavirus disease COVID-19 is currently a global problem for humanity, becoming a pandemic. From the standpoint of toxicologists, there is a need to summarize the literature on the pathogenetic and pathophysiological mechanisms of the main clinical manifestations about COVID-19 and to justify ways to optimize treatment strategies using detoxification therapy.

Purpose. Based on the analysis of literature data to identify pathogenetic mechanisms of the main clinical COVID-19 syndromes, to summarize the results of clinical and laboratory studies, clinical and hematological criteria for predicting severe cases with fatalities and to justify ways to optimize detoxification therapy.

Material and Methods. Analytical review of scientific publications was performed using abstract databases of scientific libraries PubMed, Medline and text databases of scientific publishers Elsevier, PubMed Central, BMJ Group and other VIP-databases and covers the period from January 1, 2020 to April 30, 2020. Methods of system, comparative and content analysis are used.

Results and Conclusions. Publications on the identification of infection ways with SARS-CoV-19 virus, mechanisms in formation for clinical manifestations of COVID-19 different disease variants to identify the most informative predictors of the severe disease forms that lead to fatalities are analyzed. Literature data on the mechanisms of viremia development of SARS-CoV-19, pathogenetic and pathophysiological mechanisms of virus-induced hemoglobinopathies, toxic pneumonitis, systemic hypoxemia, hyperferritinemia, cytokine “storm”, oxidative stress and endotoxicosis are summarized; improvement of detoxification therapy which included efferent treatments, the complexing agents to remove excess levels of iron and ferritin, antioxidants and antihypoxants, oxygen therapy, transfusion of immune plasma convalescents, donor blood components and stem cells, was justified.

Key Words: coronavirus disease, COVID-2019, virus-induced hemoglobinopathies, pneumonitis, detoxification therapy.
Prospect of Polypill in the Management of Cardiovascular Diseases in Bangladesh
Authors: Alam Nushrat , Mamun Md Elias Al , Islam Muhammad Rashedul
Published: July 2020

Cardiovascular disease (CVD) is one of the most prominent health issues responsible for global death currently. Just like the diverse causes of its pathophysiology, a plethora of medicines from different classes are used for the treatment and management of CVDs. However, in low and middle income countries like Bangladesh, it’s extremely difficult for patients to adhere to their treatment regimen consisting of multiple drugs from different classes as it is both expensive and inconvenient. In such scenario, a polypill or a combination of drugs containing different type of cardiovascular drugs could significantly improve the management of cardiovascular diseases in Bangladesh. Our aim was to get a real-life perspective of the prospect of commercially available polypill in Bangladesh keeping all its stakeholders such as patients, physicians and retailers in mind. A survey was conducted in two different cities (Dhaka and Comilla) and the data were correlated. We got positive response from patients, physicians and retailers. Also, the physicians came up with various combinations of drugs such as – ACEI (ngiotensin-converting enzyme inhibitors) and ARB (angiotensin II receptor blockers) (35%); ARB and CCB (calcium channel blockers) (25%) and ACEI and CCB (15%). However, disease patterns, available drugs and comorbidities in the two regions showed significant deviations as metro city based patients suffered from more severe form of CVDs. Therefore, further survey in different regions should be conducted to understand the overall disease pattern and to come up with optimum combinations for CVD patients. Beyond this discussion, it was evident that commercially available polypill has a great prospect in Bangladesh against CVDs.
Bangladesh Pharmaceutical Journal 23(1): 17-25, 2020
Preliminary Phyto-pharmacological Investigation of Duabanga Grandiflora (Roxb. ex DC.) Walpers
Authors: Sharmin Sanjida , Sifat Tahmina , Azad Afrina , Reza ASM Ali , Islam Mohammad Kaisarul , Sayeed Mohammed Abu
Published: July 2020

The methanolic extract of Duabanga grandiflora (Roxb. ex DC.) Walpers leaves was investigated to explore in-vitro anti-arthritic, thrombolytic and antioxidant potential and subsequent detection of preliminary phytochemicals. It is used for treating various diseases by folk practitioners and rural people. Initially, BSA protein denaturation method was employed to evaluate in-vitro anti-arthritic potency, where the extract exhibited potent anti-arthritic activity with 73.52±1.01% inhibition of BSA denaturation at a dose of 1000 μg/ml compared to the standard dichlofenac sodium (83.66±1.03% inhibition at 1000 μg/ml dose). In-vitro thrombolytic efficacy was determined using streptokinase (positive control) and water (negative control), and the average lysis of blood clot was found to be 31.12±1.09%, which is indicative towards the thrombolytic effect of the extract. Antioxidant activity was evaluated by the DPPH radical scavenging method followed by the total phenolic and flavonoid content determination. The crude methanolic extract revealed the IC50 value of 129.31μg/ml and 204.89μg/ml against DPPH and standard ascorbic acid, respectively. The total phenolic content and total flavonoid content of the plant leaves were observed to be 52.81±1.74μg/ml and 25.77±1.01μg/ml, respectively. The results indicate that the leaves of D. grandiflora possess favorable anti-arthritic activity, moderate thrombolytic and excellent antioxidant activity, which is demonstrating the presence of alkaloids, phenols, flavonoids and many other biologically important phyto-constituents that needs further exploration.
Bangladesh Pharmaceutical Journal 23(1): 54-60, 2020
New Drug Approvals Vol.23(1)
Authors: Hossain Md Akbar
Published: July 2020

Abstract not available
Bangladesh Pharmaceutical Journal 23(1): 80-82, 2020
Association of Diabetes with Coronary Collateral Formation in Patients with Ischaemic Heart Disease
Authors: Karim Md Fazlul , Hossain Md Tofazzal , Shahabuddin Mir Muhammad Shoyeb , Chowdhury Sanjib
Published: July 2020

Background: Although myocardial ischemia is known to be significantly related to the development of coronary collateral vessels (CCVs), there is considerable variation between patients with ischemic heart disease in the presence of collateral development. The nature of this variability is not well known. Likewise, it remains unclear whether diabetes mellitus (DM) has any effect on CCVs. The aim of this study was to evaluate the effect of DM on CCVs.

Methods: A total of 100 patients who had a stenosis of >95% in any major coronary artery in angiograms were included in the study. Of these patients, 30 patients constitute the diabetic group. Remaining 70 patients were non-diabetic. For case-control matching, 30 non-diabetic patients (mean age, 52.03± 8.69 years) were selected randomly and were included in the control group. The CCVs were graded according to the Rentrop scoring system, and the collateral score was calculated by summing the Rentrop numbers of every patient.

Results: There was no statistical difference between patients with and without DM in clinical baseline characteristics. The mean number of diseased vessels in the DM group (2.10±0.76) was higher than that in the nondiabetic group (1.63± 0.72 P.017). The mean collateral score was (1.13± 0.86) in the DM group and (1.97± 1.61) in the control group. After confounding variables were controlled for, the collateral score in the diabetic group was significantly different from that in the nondiabetic group (p=0.015).

Conclusions: Our findings suggest that CCV development is poorer in patients with DM than in patients without DM. Thus, we can speculate that DM is an important factor affecting CCV development.

Cardiovasc. j. 2020; 12(2): 89-95
Blood Lactate Level as Predictor of Early Outcome after Off-Pump Coronary Artery Bypass Grafting
Authors: Aktar Nasrin , Rahim AM Asif , Shahidullah AYM , Hossain AHM Iftekher , Ahmed Farooque
Published: July 2020

Background: Identification of predictors of morbidity and mortality is an important issue for the management of cardiac surgical patients. Elevated lactate concentrations in the immediate postoperative period reflect unmet metabolic demand and may be associated with outcome.

Methods: A prospective observational study was carried out in the department of cardiac surgery, at National Heart Foundation Hospital& Research Institute(NHFH&RI), Dhaka. commencing from July 2016 to March 2018. In all Adult patients irrespective of sex undergoing elective off-pump coronary artery bypass grafting (OPCABG). Purposive sampling was applied with patient with blood lactate level < 3 mmol/L 6hours after shifting from OT to ICU in Group-A and blood lactate level ≥3mmol/l, 6hours after shifting to the ICU in Group-B.Postoperative early adverse outcomes were analyzed in both the patient groups.

Results: Blood lactate level 6 hours after ICU transfer is an independent predictor for prolonged mechanical ventilation time, (OR 2.540, 95% CI 1.781-3.621, p= <0.001).prolonged ICU stay, .(OR 1.767, 95% CI 1.348-2.315, p=< 0.001) pulmonary complication (OR 1.503, 95% CI 1.104-2.046, p= 0.010).and renal dysfunction(OR 1.460, 95% CI 1.156-1.843, p= 0.001). following off-pump coronary artery bypass grafting. Other risk factors for adverse outcome including, low LVEF, diabetes mellitus, blood transfusion and inotropic support were also found to be predictors of major complications in our study.

Conclusion: The findings of this study permits to conclude that blood lactate level 6hours after ICU transfer is associated with an increased risk of postoperative early adverse outcome after off-pump coronary artery bypass grafting. It is found that lactate is an independent predictor of major postoperative complications. So, achieving normal blood lactate level following OPCABG is essential for minimizing postoperative adverse outcome.

Cardiovasc. j. 2020; 12(2): 120-125