bluuebunny/crossref_metadata_2025 huggingface dataset:
From the Soviet Folksong Research: Between Free Choice and Obligation
Authors: Stundžienė Bronė
Published: July 2023

The history of the Soviet folkloristics has been underresearched until now. Usually, attention in centered only on the main directions and results of the works carried out during that period. In these folksong studies, these include creating classification system for folksong genres, as well as editing and publishing so-called fundamental sources of folklore – the multivolume collection of the “Book of Lithuanian Folk Songs”. So far, the generation of the Soviet-period folklorists or research activities of its representatives, especially the options and alternatives that were available to them, have hardly been discussed, if at all. The 100th anniversary of Pranė Jokimaitienė, which was celebrated last year, encouraged to take a look at her folklore studies precisely in the context of the Soviet ideological demands, which were relevant to this sphere of research. However, her case is rather exceptional, since the biography of this scholar, who grew up during the interwar period in the independent Lithuania, was for various reasons completely inappropriate to the Soviet regime. Therefore, a fresh look at the folklore studies by P. Jokimaitienė written during the Soviet-period, and observations in the field of possible ideological tensions that can be discerned in them enables to identify a very strong person who, while moderately using the “inner censor” tool that was common in the public discourse, at the same time managed to resist any moral compromises.

The interpretation of research works by P. Jokimaitienė proposed in the article allows us to draw a conclusion that, while following the unified Soviet program for folklore research, she never did anything superficially – both investigating the folksong composition as a social or artistic discourse and writing popular texts on folklore. Most of her arguments are well documented and constructive, while her notion of folksongs is based on philological assumptions and still relevant to the Lithuanian folkloristics today.
Under the Hood of Ideology: What Was the Soviet Family Life?
Authors: Bleizgienė Ramunė
Published: July 2023

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Reviving Songs from Panemunė
Authors: Žičkienė Aušra
Published: July 2023

Pieśni Poniemnia, pieśni Beskidu Sądeckiego: wykorzystanie efektów badań etnomuzykologicznych w dydaktyce i projektach artystycznych, śpiewają studentki i studenci Uniwersytetu Warszawskiego; koncepcja i koordynacja projektu, przygotowania wykonawców, wybór materiałów i opracowanie Anastasiya Niakrasava, Warszawa: Uniwersytet Warszawski, Wydział Nauk o Kulturze i Sztuce: Instytut Muzykologii UW, 2022, 1 płyta CD + broszura, 72 s., ISBN 978-83-67514-00-2
Peningkatan Pemecahan Masalah Siswa Kelas 3 SD Negeri 02 Rowosari Kecamatan Ulujami menggunakan Model Problem Based Learning
Authors: Melanti Riska
Published: July 2023

The ability to solve problems is one of the important abilities to be learned and important to be mastered by students. Aini and Siswono (2014) state that solving math problems is an important part of learning mathematics. improving problem solving for grade 3 students at SD Negeri 02 Rowosari Subdistrict Ulujami using the PBL model. This research is a Classroom Action Research (CAR) using the research design model of Kemmis and Mc Taggart (1988). The subjects of this study were all 3rd grade students of SD Negeri 02 Rowosari, Ulujami District, Pemalang Regency, semester 1 of the 2022/2023 academic year, totaling 24 students. The results of this study are that there is an increase in the problem solving of solving student material based on the stages of Polya through 2 cycles with each cycle consisting of 2 meetings.
Implementasi Metode Proportional Integral Derivative (PID) Ziegler Nichols pada Kontrol Mesin Penyangrai Biji Kopi
Authors: Nggala Liberius Harsen , Nachrowie Nachrowie , Subairi Subairi
Published: July 2023

Kendali PID telah dimanfaatkan dalam berbagai kontrol mesin sederhana maupun mesin kompleks. Kopi merupakan komoditas pertanian yang banyak digunakan sebagai bahan makanan dan minuman. Penyangraian biji kopi diperlukan sebelum dapat diolah lebih lanjut (dikonsumsi). Penelitian ini dilakukan untuk membuat mesin penyangrai biji kopi terkontrol otomatis dengan memanfaatkan metode PID Ziegler-Nichols tipe-1. Mesin penyangrai biji kopi ini dibuat dengan rangkaian wadah sangrai, motor DC, motor servo, ESP32, sensor termokopel, sensor load cell, kompor keramik, dan komponen pendukung lainnya, mesin ini juga dilengkapi dengan fitur tiga variasi level kematangan biji kopi yang dapat berpengaruh pada variasi kepahitan dari biji kopi yang dihasilkan yaitu, level “light” (3-5% kadar air), “medium” (5-8% kadar air), dan “dark” (8-12% kadar air). Kendali PID Ziegler-Nichols diimplementasikan pada mesin ini untuk mengontrol derajat putaran motor servo kran gas pada kompor agar suhu pada wadah sangrai sesuai dengan set point yang ditentukan. Berdasarkan hasil penelitian yang telah dilakukan, implementasi kendali PID ini berhasil dilakukan dengan set point suhu yang digunakan, 145˚C dengan nilai KP sebesar 7,2, KI sebesar 0,034, dan KD sebesar 413,6. Rata-rata eror dari pengukuran alat penelitian yang diperoleh yaitu untuk suhu sebesar 0,32%, dan untuk berat sebesar 0,24%.
A retrospective analysis of the histology of resected polyps and colonoscopy quality parameters in Belgium
Authors: Macken E , Van Dongen S , Van Hal G
Published: July 2023

Background and aims: adenoma detection rate is a well known quality parameter for colonoscopy. However recently other quality parameters have emerged. We wanted to evaluate the histology of the resected polyps, different quality indicators of colonoscopy and post colonoscopy colorectal cancer (PCCRC) in Belgium and analyzed data about colonoscopies performed between 2008-2015.

Methods: Reimbursement data on colorectal related medical procedures from the Intermutualistic Agency were linked with data on clinical and pathological staging of colorectal cancer and with histologic data of resected polyps available at the Belgian Cancer Registry over a period covering 8 years (2008-2015).

Results: 298,246 polyps were resected in 294,923 colonoscopies, of which 275,182 were adenomas (92 %) and 13,616 were SSLs (4%). There was a significant but small correlation between the different quality parameters and PCCRC. Post colonoscopy colorectal cancer rate after 3 years was 7.29 %. There were marked geographic differences in Belgium concerning adenoma detection rate, sessile adenoma detection rate and post colonoscopy colorectal cancer.

Conclusion: Most resected polyps were adenomas, only a small percentage involved sessile serrated lesions. There was a significant correlation between adenoma detection rate and other quality parameters, and a small but significant correlation between PCCRC and the different quality parameters. The lowest post colonoscopy colorectal cancer rate was reached with an ADR of 31.4 % and a SSL-DR of 1.2 %.
INCIDÊNCIA E PREVALÊNCIA DE ÚLCERAS DE PRESSÃO EM DOENTES ADMITIDOS EM SERVIÇO DE EMERGÊNCIA HOSPITALAR: UMA REVISÃO DA LITERATURA
Authors: Silvestre Fábio Miguel Mendes , Entradas Carolina Alexandra Corte Negra
Published: July 2023

Introdução: As úlceras de pressão são uma complicação causada pela combinação de fatores como a humidade, cisalhamento, fricção e pressão, sendo um problema comum principalmente entre a população idosa. Este artigo apresenta como objetivo conhecer a realidade da incidência e prevalência das úlceras de pressão em serviços de emergência hospitalares, de modo a consciencializar para que seja concedido cada vez mais ênfase aos cuidados direcionados à prevenção de úlceras de pressão.Métodos: Revisão sistemática da literatura, com inclusão de artigos científicos publicados entre janeiro de 2010 até junho de 2023. Foram selecionados cinco artigos, seguindo a normativa PRISMA.Resultados: Os artigos revelam uma incidência elevada de úlceras de pressão em doentes admitidos em serviços de emergência, nomeadamente de grau I e II, essencialmente associadas a um tempo de permanência prolongado no serviço.Conclusão: As úlceras de pressão são uma complicação real da permanência prolongada de doentes em serviço de emergência, sendo estas descobertas fundamentais para alertar para a necessidade de adotar medidas preventivas logo desde a chegada de doentes ao serviço de emergência.
Los retos de la protección de las personas informantes en España tras la aprobación de la Ley 2/2023: un derecho en vías de consolidación
Authors: Viguri Cordero Jorge Agustín
Published: July 2023

El 20 de febrero de 2023, se aprobó la Ley 2/2023 reguladora de la protección de las personas que informen sobre infracciones normativas y de lucha contra la corrupción, por la que transpone la Directiva 2019/1937 relativa a la protección de las personas que denuncian infracciones del Derecho de la Unión. El objeto del presente estudio radica en poner de relieve el deficitario proceso de transposición de esta Directiva, especialmente, de aquellos aspectos más críticos que contempla esta ley. Consecutivamente, se acomete el margen de mejora que requieren algunos preceptos legales que no solo comprometen la efectividad de este acto legislativo de la Unión Europea, sino que generan dudas de encaje constitucional con otras normas nacionales de carácter general y sectorial. Finalmente, se identifican algunas de las lagunas más destacadas que presenta el ámbito objetivo y subjetivo de la ley española con un fiel reflejo de otras legislaciones europeas más consolidadas, para así proponer a modo de lege ferenda respuestas sobre las que debería pivotarse una futura reforma de la misma.
Court-Ordered Interim Measures in International Arbitration: A Comparative Approach
Authors: Bantekas Ilias
Published: July 2023

This paper argues that there is a distinct cross-border law concerning court-ordered interim measures in aid of international arbitration, which is made up of two key (intertwined) sources, namely: the relevant provisions of the UNCITRAL Model Law on International Commercial Arbitration and supporting case law and legislation in both Model Law states and non-Model Law states. The principles identified in this paper are assumed to qualify as general principles of law. In order for a court at the seat to grant interim relief in international arbitral proceedings the requesting party must demonstrate a prima facie case worthy of consideration, the likelihood of irreparable harm and a balance of inconvenience. There is at present no general consensus as to ex parte interim measures, with many states and national courts showing significant reluctance to grant these on account of the absence of procedural guarantees that they entail. In equal measure, in the absence of bilateral or multilateral treaties that allow national courts to recognize and enforce foreign interim measures in respect of arbitral proceedings seated abroad, states are equally reluctant to allow parties seated in other jurisdictions to approach their courts for interim relief on the ground that the other party has assets or interests there. Although the courts of some powerful nations allow for such requests, there is no general rule in this regard and none is expected in the near future.
PENGARUH PENGGUNAAN MADU DALAM ORAL HYGIENE TERHADAP STATUS KESEHATAN MULUT PADA PASIEN PNEUMONIA YANG TERPASANG INTUBASI DI RUANG ICU RSUD SITI FATIMAH AZ-ZAHRA PROVINSI SUMATERA SELATAN TAHUN 2022
Authors: Nurjannah  , Saputri Deah Karina , Syafriati AnI
Published: July 2023

Pneumonia adalah penyakit infeksi akut yang mengenai jaringan (paru-paru) yang disebabkan oleh beberapa mikroorganisme seperti virus, bakteri, jamur, maupun mikroorganisme lainnya. Pneumonia terkait ventilator (VAP) masih menjadi hal serius yang harus ditangani dan dicegah. VAP dapat dicegah salah satunya melalui perawatan mulut atau Oral Hygine. Penggunaan madu dalam oral hygiene berguna untuk mengatasi masalah kesehatan mulut. Didalam madu terdapat kandungan zat antibakteri, zat antibiotik sekaligus desinfektan yang sangat efektif menghambat pertumbuhan bakteri patogen di dalam mulut. Jenis penelitian ini menggunakan desain pra-experimental dengan pendekatan (One Group Pre Post Test  Design). Subjek studi kasus ini merupakan pasien pneumonia yang terpasang intubasi. Peneliti melakukan 4 kali observasi status kesehatan mulut menggunakan lembar observasi Oral Assesment Scale (OAS). Hasil penelitian ini menunjukkan bahwa hasil uji statistik parametrik test didapatkan p value = 0,000 (p value < 0,05) sehingga ada pengaruh yang signifikan antara sebelum dan setelah melakukan oral hygiene menggunakan madu terhadap status kesehatan mulut pasien pneumonia yang terpasang intubasi diruang ICU RSUD Siti Fatimah Provinsi Sumatera Selatan. Saran untuk tenaga medis khususnya perawat dapat mengaplikasikan pemberian intervensi oral hygiene menggunakan madu untuk peningkatan status kesehatan mulut pada pasien yang terintubasi yang dirawat di ruang ICU.
HUBUNGAN MUTU PELAYANAN KEPERAWATAN TERHADAP KEPUASAN PASIEN LANSIA POLI PENYAKIT DALAM
Authors: R.A. Fadila  , Endang Sulastri
Published: July 2023

Kepuasan pasien masih menjadi masalah di beberapa rumah sakit di Indonesia bahkan dunia. Kualitas pelayanan keperawatan sebagai indikator mutu pelayanan kesehatan merupakan salah satu faktor penentu citra institusi pelayanan kesehatan di mata masyarakat. Tujuannya untuk mengetahui hubungan mutu pelayanan keperawatan terhadap kepuasan pasien lansia. Jenis penelitian kuantitatif dengan menggunakan    kerelasi melalui pendekatan cross sectional, menggunakan deskriptik analitik.          Populasinya pasien lansia poli penyakit dalam di RSUD Siti Fatimah Provinsi Sumatera Selatan Tahun 2023, jumlah sampel 44 responden. Menentukan responden dengan teknik accidental sampling, pengumpulan data dilakukan dengan kuesioner yang kemudian   dianalisis uji statistik dengan uji chi square dengan α = 0,05. Yang mendapatkan mutu pelayanan kurang baik dan kurang puas sebesar 29,5 % dengan jumlah 13 responden. Mutu pelayanan baik dan puas sebesar 45,5 % dengan jumlah 20 responden. Diperoleh ρ value sebesar 0,002 dengan tingkat keeratan kuat. Berdasarkan hasil uji statistik menggunakan uji chi square ρ value 0,002 < α = 0,05 maka Ho ditolak dan H1 diterima. Ada hubungan mutu pelayanan terhadap kepuasan pasien lansia poli penyakit dalam di RSUD Siti Fatimah. Diharapkan mutu pelayanan rumah sakit ditingkatkan lagi terutama di lima indikator mutu agar pasien merasa puas dengan pelayanan yang diterimanya.
ASUHAN KEBIDANAN BERKELANJUTAN PADA NY.S, NY.A, NY.A DI PMB DESI ARIANI, S.Tr.Keb
Authors: YANTI DWI
Published: July 2023

Upaya yang dapat dilakukan untuk menekan AKI dan AKB yaitu dengan terlaksananya pemeriksaan Continuity of Care. Asuhan Continuity of Care merupakan asuhan secara berkesinambungan dari hamil sampai dengan keluarga berencana sebagai upaya penurunan AKI dan AKB. Pelayanan yang dicapai dalam Asuhan Continuity of Care adalah ketika terjalin hubungan dengan terus menerus antara seorang ibu dan bidan. Tujuan laporan adalah memberikan Asuhan Kebidanan Berkelanjutan mulai dari hamil, bersalin, nifas, BBL dan KB dengan asuhan kebidanan  komplementer pada masa nifas dengan pemberian tehnik Pijat Oksitosin terhadap peningkatan  produksi  ASI  pada Ny.S , Ny. A dan Ny. A. Metode yang digunakan dalam asuhan Continuity of Care adalah jenis penelitian Deskriptif dengan mennggunakan metode pendekatan studi kasus. Hasil laporan yang didapatkan dari asuhan  Continuity of Care diberikan komplementer terapi pijat oksitosin pada ketiga pasien dengan terapi yang sama pada hari pertama pemberian terapi  diberikan lembar observasi (pretest) dengan hasil < 5 dimana masuk dalam kategori ASI Kurang dan dievaluasi pada hari ketujuh diberikan lembar post test dengan hasil > 5 dimana masuk dalam kategori ASI cukup. Kesimpulan laporan ini adalah Setelah melakukan asuhan pijat oksitosin Ny. S, Ny. A, dan Ny. A mengalami peningkatan produksi ASI dan tidak ditemukan kesenjangan antara teori dan praktik.
GAMBARAN CEMARAN BAKTERI Staphylococcus aureus PADA LIPSTIK CAIR TESTER
Authors: Monica Faris , Qorry Aina Ganea , Irianti Rukmana Dita
Published: July 2023

Lipstik cair merupakan salah satu kosmetik yang sering digunakan oleh wanita. Adanya kandungan air pada bahan baku lipstik dapat menjadi media pertumbuhan mikroba yang baik.. Penggunaan lipstik cair tester kemungkinan memiliki angka kuman yang tinggi karena sering kontak langsung dengan kulit dan bibir pengguna. Penelitian ini bertujuan untuk mengetahui adanya cemaran bakteri Staphylococcus aureus pada lipstik cair tester. Penelitian ini adalah penelitian deskriptif. Variabel pada penelitan ini adalah variabel tunggal yaitu Bakteri Staphylococcus aureus pada lipstik cair tester. Jumlah sampel sebanyak 18 sampel dari toko kosmetik di pasar dan mall  wilayah Kota Samarinda. Hasil dari penelitian ini adalah ditemukan sebanyak 61% sampel lipstik cair tester tercemar bakteri staphylococcus aureus. Disarankan kepada masyarakat untuk memperhatikan personal hygiene agar tidak terkontaminasi bakteri Staphylococcus aureus dengan mencuci tangan ataupun menggunakan antiseptik baik sebelum ataupun setelah mencoba lipstik cair tester.

Lipstik cair merupakan salah satu kosmetik yang sering digunakan oleh wanita. Adanya kandungan air pada bahan baku lipstik dapat menjadi media pertumbuhan mikroba yang baik.. Penggunaan lipstik cair tester kemungkinan memiliki angka kuman yang tinggi karena sering kontak langsung dengan kulit dan bibir pengguna. Penelitian ini bertujuan untuk mengetahui adanya cemaran bakteri Staphylococcus aureus pada lipstik cair tester. Penelitian ini adalah penelitian deskriptif. Variabel pada penelitan ini adalah variabel tunggal yaitu Bakteri Staphylococcus aureus pada lipstik cair tester. Jumlah sampel sebanyak 18 sampel dari toko kosmetik di pasar dan mall  wilayah Kota Samarinda. Hasil dari penelitian ini adalah ditemukan sebanyak 61% sampel lipstik cair tester tercemar bakteri staphylococcus aureus. Disarankan kepada masyarakat untuk memperhatikan personal hygiene agar tidak terkontaminasi bakteri Staphylococcus aureus dengan mencuci tangan ataupun menggunakan antiseptik baik sebelum ataupun setelah mencoba lipstik cair tester.
CONTINUOUS MIDWIFERY CARE IN NY. W, NY. N, NY. F AT PMB IMELDA, S.ST TULANG BAWANG YEAR 2022/2023
Authors: Yesika Tusiana  , Supriyati  , Yetty Dwi Fara
Published: July 2023

Even though pregnancy, childbirth and menopause are natural processes, there is still a chance that something could go wrong with the woman or her baby. Warm breast compresses as a postpartum intervention aim to relieve pain, accelerate healing, improve blood flow, and relax the client by breaking down fibrous tissue and relaxing muscles. The purpose of this study was to find out whether Mrs.W and Mrs.F at PMB Imelda, S.ST, Tulang Bawang Regency in 2023 experienced a decrease in breast swelling. Case studies and descriptive methods based on interviews and archival research are viable options for gathering information for research. The research was conducted in 2023 at PMB Imelda, S.ST, Tulang Bawang Regency, from January to April. Pregnant women in the PMB Imelda S.ST, Tulang Bawang Regency in 2023 with a gestational age > 36 weeks were the subjects in the cases taken. The results showed that postpartum women whose breasts were swollen experienced a reduction in swelling after being given warm compresses. Warm compresses have been shown to reduce pain by constricting blood vessels, dulling the sensation of pain, and dampening the activity of nerve endings associated with muscles. Suggestions for health workers can boost the standard of midwifery care and ensure that patients get continuity of care.
Bioquímica estrutural: exercícios de identificação da estrutura de biomoléculas
Authors: Massaharu Hassunuma Renato , Carvalho Garcia Patrícia , Nunes Messias Sandra Heloisa
Published: July 2023

Os exercícios propostos neste livro apresentam a estrutura bioquímica de biomoléculas representadas na forma de fórmulas estruturais ou no modelo de bolas e varetas. Neste último modelo, os átomos são representados por cores no padrão CPK, estabelecidas em 1952 pelos químicos Robert Corey e Linus Pauling, e posteriormente melhoradas por Walter Koltun em 1965. Caso tenha dúvidas, no Quadro 1, apresentado no final do livro, disponibilizamos uma tabela de cores do padrão CPK.
The Role of Customization, Security, and Flexibility in Enhancing Trust and Continuance Intentions of Digital Payment Services: Insights from Pakistan
Authors: Bashir Roshan , Sheikh Muhammad Ramzan , Arshad Tabassum , Asghar Neelum
Published: July 2023

Nowadays e-banking via different platforms of bank is very common in European countries. In Pakistan, the intention of digital transactions services is very useful and common nowadays. However, some people’s intention is that the transactions through mobile services is not trusted for that reason the adoption of digital transactions services is still in the initial stage. This study is based on the diffusion of the invention theory and inculcate the experiences of intention to use digital transactions services by a trust-facilitating role. The data is collected through the survey method from ordinary end users who are making the digital transactions via Jazz Cash and Easy paisa within a Pakistan and the current study’s aim is to give guide lines to the administrators of digital transactions service providers to strengthen the customization, security features, flexibility, and which wins the trust of customers.
АНАЛИЗ ТРАНЗИТНЫХ НАПРАВЛЕНИЙ ЖЕЛЕЗНОДОРОЖНЫХ КОРИДОРОВ НА ПРИМЕРЕ ТРАНСКАСПИЙСКОГО МЕЖДУНАРОДНОГО ТРАНСПОРТНОГО МАРШРУТА НА КАЗАХСТАНСКОМ УЧАСТКЕ
Authors: Кобдикова Шамсигуль , Рамазан Бекбол , Аримбекова Перизат
Published: July 2023

Влияния различных логических и экономических показателей для эффективного функционирования железнодорожных транспортных коридоров на качество гармонизации работы транспорта. Одним из самых важных направлений улучшения деятельности железнодорожной инфраструктуры в наше время являются информационные технологии при эксплуатации, отвечающие также за безопасность, надежность и «комфортность» эксплуатации инфраструктуры. Помимо этого, значительной проблемой является отсутствие официального и предсказуемого графика портовых отправок. Учитывая важность для страны экспортно-импортных и транзитных перевозок через морские порты, а также усилия АО "НК "КТЖ" по развитию портовой инфраструктуры и привлечению грузопотоков, изменению внешней ситуации с ограничениями на транспортировку грузов через Россию, совершенно естественно повышение роста перевозок через порты Каспия.
Feminism and Gender Disclosure in Girish Karnad's Nagamandala
Authors: Srinivasraj B. , Souda Dr. Saveen
Published: July 2023

B. Srinivasraj, Dr. Saveen Souda
Use of high energy milling and porosity insertion in the development of the Mg-Zn system aiming biomedical applications
Authors: Costa Viviane S. , Souza Willian , Pinto Pércio M. , Rodrigues Junior Durval
Published: July 2023

The development of metal alloys with porosity controlled by powder metallurgy has shown to be suitable for obtaining biomaterials with the control of mechanical strength and modulus of elasticity, in addition to the possibility of controlling open porosity, which is essential for osseointegration. Magnesium alloys have shown encouraging results when used as tissue engineering scaffolds. Although a considerable number of studies encourage the use of magnesium alloys in bioactive implants for load-bearing in orthopedic applications, a great deal of research effort is still essential to assess in vivo, the long-term capability of such supports. Due to the excellent physical and mechanical properties of magnesium compared to other permanent (non-degradable) elements, porous magnesium alloys have become good candidates to develop biodegradable supports for bone treatments. Porous magnesium alloys could be used in applications where it would be interesting to use a biodegradable metallic material, while maintaining the requirements of mechanical strength, elastic modulus, corrosion resistance and adequate osseointegration. In this work, a new route of processing porous alloys of the MgZn system using high energy milling, via powder metallurgy, will be evaluated.
Entrepreneurship in biotechnology in Brazil: the path to innovation development
Authors: Tonon Adriana Pagan , Macedo Fernando Luiz , Amaral Creuza Sayuri Tahara
Published: July 2023

Studies and debates on entrepreneurship, innovation, and biotechnology have been highlighted on the world stage. Considering this context, it is necessary to evaluate innovation and its consequences for the entrepreneur because innovation is a fundamental requirement for the success of the entrepreneur, especially when it involves the biotechnology area. Innovation has the power to create a new product, a market success, and generate economic benefits for the company. In this context, this work aims to understand through literature research how the insertion of innovation in entrepreneurship can contribute to the biotechnology area. To gain the necessary understanding of the theme, the methodology used was bibliographic research with the purpose of collecting and synthesizing existing knowledge. The results found showed that there are gaps between entrepreneurship and the process of searching for innovation, the selection of ideas, and the challenges facing the changes needed for the entrepreneur's initiatives to be successful. In the biotechnology area, entrepreneurship can assist in innovation processes as well as strengthen the capacity for competitiveness. Therefore, this research puts into debate the relevant aspects of entrepreneurship, the innovation process in the biotechnology area, and its impact on the economy and society.
Effect of synthesis temperature on crystallinity, morphology and cell viability of nanostructured hydroxyapatite via wet chemical precipitation method
Authors: Rosa Andriele L. , Farias Luana R. , Dias Vinicius P. , Pacheco Otávio B. , Morisso Fernando D.P. , Rodrigues Junior Luiz F. , Sagrillo Michele R. , Rossato Aline , Santos Luis A.L. , Volkmer Tiago M.
Published: July 2023

Hydroxyapatite (HA) is the main natural mineral constituent of bones and is a good alternative for biomedical applications because it is osteoconductive, non-allergenic, and non-carcinogenic, which ensures high biocompatibility. A commonly used method for obtaining hydroxyapatite is the wet route, which is simple and low-cost, produces only water as a final residue, and provides HA with a crystallinity comparable to that of bone tissue, which favors its biocompatibility. Therefore, the objective of this work is to synthesize hydroxyapatite via the wet chemical precipitation method at different temperatures (4°C, 30°C, 50°C, or 70°C) to observe the influence of temperature on crystallinity, morphology, and cytotoxicity. The results of X-ray diffraction show that all syntheses resulted in pure hydroxyapatite, while increasing the temperature led to higher crystallinity (10.6% to 56.2%) and the crystal size was slightly affected. The increase in temperature changed the particle shape from irregular to needle-like. Cell viability was tested by PicoGreen® in VERO cells for samples at concentrations of 30 and 300µg/mL, and the samples synthesized at 4°C, with lower crystallinity, caused less DNA damage to cells compared to the negative control.
Robotic arm inertial control for recreational child physiotherapy application
Authors: Mendes Nascimento Jean , Dos Santos Brito Caroline , Davi Castro Frazão Eric , Santos Mera Gabriel Augusto , Alves Aniceto da Silva Guilherme , Venceslau de Melo Hugo Guilherme
Published: July 2023

According to reports from physical therapists, physiotherapy presents a painful and uninteresting process because it distances itself from the ludic, which is a natural essence of the human being, and easily attracts children when applied. In 2021, the “Robotic System for Children's Physiotherapy with Recreational Activities” project was developed, which consisted of a robotic arm to assist in the physiotherapy process of children with Cerebral Palsy. According to the conclusions of the initial project, the developed control was effective in what was proposed but not sufficient for project application in rehabilitation environments In this way, this work present a new control that is safer and that allows its application helping in the rehabilitation of these children. This new control allows the robotic arm to reproduce the movements of the human arm, so that the movement of the forearm, arm and hand are reproduced independently, simultaneously and in real time. Therefore, the prototype control operates reliably and robustly, achieving what was aimed at, a safer and more efficient physiotherapeutic process for users.
Survival Times of Breast Cancer Patients in Nigeria: Application of Cox and Parametric Survival Models
Authors: F.C. Akanno , C.C. Obasi , U.M. Chukwuocha , U.W. Dozie , C.L.U. Ori , G.I. Sule , A. Ijeoma-Ogu , D.C. Innocent
Published: July 2023

In this study, we modeled the survival time of breast cancer patients in Nigeria using five survival models, namely the Cox model, the exponential model, the lognormal model, the logistic model, and the Weibull model. The Akaike information criterion (AIC) and Bayesian information criterion (BIC) were used as performance metrics for the selection of the best-fit model. The Cox proportional hazard (CPH) model was the best model for the cancer data. We also noted that the median patient survival time was 295 days. The Kaplan-Meier test was used to compare the survival curves. The CPH model was used to model the data. We observed that the neoadjuvant therapy covariate had a significant effect on the survival time of the breast cancer patients (p < 0.05). This suggests that it has a considerable impact on Nigerian breast cancer patients' survival rates. This study could result in more efficient cancer treatments and has substantial implications for the management and care of breast cancer patients in Nigeria. It further extends the work of Awodutire et al. (2017).
Serological Evidence of Hepatitis B Virus among Secondary School Students in a Community in Plateau State, Nigeria
Authors: E.I. Bigwan , R.N. Alexander , D.F. Jurbe , J.M. Banda , Z. Sheyin
Published: July 2023

Hepatitis B virus is among the common viral infectious agents of global public health concern because it increases the risk of hepatocellular cancer, liver fibrosis, and mortality from liver disease. The study's objectives were to detect hepatitis B surface antigen (HBsAg) in the blood samples of students of Government Secondary School, Bet, Pankshin, Plateau State. A cross-sectional analytical study was conducted between October and November 2018. Blood samples were collected from 168 participants which were analysed for HBsAg using a One-step Rapid Strip (Royal Care) and HBeAg by Combo Test Device (Skytech USA). Data were analyzed using SPSS version 21.0 (USA). P-values < 0.05 were considered significant. An overall 7.1% of the 168 samples analysed were seropositive for HBsAg and 6.7% for HBeAg. Males had a seropositivity of 11.6%, whereas females had a seropositivity of 4.0% (p = 0.061). The distribution of HBsAg in relation to age group was higher in the age group 13-19 years with 7.3% and the lowest in the age group 6-12 years with 6.7%. Those with history of sexual exposures had a seropositivity of 14.3% (p = 0.174; OR = 0.371, those with history of exposure to sharp objects had 7.3% (p = 0.869; OR = 0.876), those with the history of blood transfusion had none (p = 0.319; OR = 1.00), participants without history of ever screened for the virus had a seropositivity of 7.4% (p = 0.529; OR = 1.00) while the alcoholics had 13.6% (p = 0.205; OR = 0.416. It is imperative to act quickly to prevent liver disease morbidity and mortality given the seropositivity of 7.1% of HBV, which is of considerable public health concern. There is need to intensify campaign awareness and vaccination against HBV among all unvaccinated age groups.
Anteseden Pembelian Makanan Organik di Indonesia
Authors: Peruzzi Mochammad Rafii , Alfiandi Muhammad Fadi , Gunadi Willy
Published: July 2023

Meningkatnya konsumsi manusia menyebabkan masalah pada lingkungan. Di sisi lain, banyak masyarakat Indonesia yang mulai menerapkan gaya hidup yang sehat dengan cara mengkonsumsi produk organik. Hadirnya fenomena COVID-19 juga telah memberikan dampak kepada pola hidup masyarakat. Penelitian ini bertujuan untuk menganalisis keterkaitan antara health consciousness, environmental knowledge, environmental concern, perceived value, organic food knowledge, attitude dan green purchase intention. Pengumpulan data dilakukan melalui penyebaran kuesioner secara online terhadap konsumen yang yang membeli dan mengkonsumsi makanan organik menggunakan penghasilan sendiri dan setiap bulannya melakukan pembelian produk makanan organik yang dilakukan dengan metode purposive sampling terhadap sebanyak 193 responden. Analisa data dalam penelitian ini dilakukan menggunakan metode PLS-SEM. Hasil pengujian hipotesis diperoleh temuan health consciousness, environmental knowledge, environmental concern, perceived value, dan organic food knowledge secara positif berdampak kepada attitude, subjective norm dan attitude secara positif berdampak kepada green purchase intention, green purchase intention secara positif berdampak kepada actual green purchase.
Pengaruh Rata Lama Sekolah,Umur Harapan Hidup Serta PDRB Per Kapita Terhadap Kemiskinan Melalui Analisis Jalur Pengangguran di Daerah Istimewa Yogyakarta
Authors: Bayu Bagas Samudra Ahmad , Wahed Mohammad
Published: July 2023

Kemiskinan merupakan permasalahan umum di Negara-negara berkembang. Kemiskinan muncul karena ketidakmampuan sebagian masyarakat untuk menyelenggarakan hidupnya sampai suatu taraf yang dianggap manusiawi Penelitian ini bertujuan untuk mengetahui pengaruh tidak langsung antara komponen IPM yaitu Rata-rata Lama Sekalah, Umur Harapan Hidup dan PDRB Perkapita terhadap kemiskinan melalui Tingkat Pengangguran Terbuka di Provinsi Yogyakarta. Penelitian ini menggunakan data sekunder dengan metode kuantitatif. Analisis data menggunakan analisis jalur dengan uji sobel sebagai pengujianya. Data time series menggunakan periode tahun 2002-2021. Hasil penelitian menunjukkan bahwa Tingkat Penagngguran Terbuka mampu menjadi variabel antara (intervening) yang menjelaskan pengaruh tidak langsung antara Umur Harapan Hidup terhadap tingkat kemiskinan. Selain itu pengaruh tersebut memiliki hubungan positif yang artinya ketika umur harapan hidup masyarakat mengalami peningkatan, maka akan menambah tingkat kemiskinan.
Efektivitas Manajemen Pendidikan dalam Membentuk Karakter Diri
Authors: Syafi’i Akhmad , Saied Muhammad , Rohman Hakim Arif
Published: July 2023

Penelitian ini bertujuan untuk menguji efektivitas manajemen pendidikan dalam membentuk karakter diri pada peserta didik. Metode penelitian yang digunakan adalah metode survei dengan mengumpulkan data melalui kuesioner yang diberikan kepada peserta didik dan guru di sekolah yang dipilih. Sampel penelitian adalah siswa dan guru dari sebuah sekolah menengah pertama di wilayah tertentu. Hasil penelitian menunjukkan bahwa manajemen pendidikan yang baik memiliki pengaruh positif dan signifikan terhadap pembentukan karakter diri pada peserta didik. Faktor-faktor seperti kepemimpinan kepala sekolah, pola komunikasi guru-siswa, dan dukungan lingkungan sekolah memiliki pengaruh yang penting dalam membentuk karakter diri. Implikasi penelitian ini adalah pentingnya manajemen pendidikan yang efektif dalam membentuk karakter peserta didik dan peran penting kepala sekolah dan guru dalam menciptakan lingkungan pendidikan yang kondusif. Temuan dari penelitian ini dapat digunakan sebagai referensi bagi pihak sekolah dan stakeholder pendidikan untuk mengembangkan program dan kegiatan yang dapat membantu meningkatkan karakter diri peserta didik di sekolahHasil penelitian mengenai efektivitas manajemen pendidikan dalam membentuk karakter diri menunjukkan beberapa kesimpulan penting. hasil penelitian ini sangat penting bagi pengembangan pendidikan karakter di Indonesia dan memperbaiki kualitas manajemen pendidikan di sekolah
Analisis Pendapatan Petani Padi Rawa Lebak dengan Sistem Surjan di Desa Tebing Gerinting Utara Kecamatan Indralaya Selatan Kabupaten Ogan Ilir Sumatera Selatan
Authors: Mulyana Eka , Novita Sari Serly , Januarti Indri
Published: July 2023

Pertanian Indonesia merupakan Pertanian tropika dikarenakan sebagian besar daerahnya berada pada daerah tropis yang langsung dipengaruhi oleh garis khatulistiwa, yang memotong Indonesia hampir menjadi dua bagian. Tujuan dari penelitian ini adalah untuk Menghitung pendapatan petani padi lahan rawa lebak di Desa Tebing Gerinting Utara. Pengambilan data sampel yang digunakan adalah sampel acak sederhana (Simple Random Sampling). Pengumpulan data yang digunakan terdiri dari data primer dan data sekunder. Data yang diperoleh dari hasil wawancara diolah secara sistematis. Analisis data yang digunakan adalah analisis data deskriptif kuantitatif, yaitu data yang diperoleh dalam bentuk angka kemudian hasil data yang didapatkan dipaparkan dalam bentuk uraian yang sistematis dengan menggunakan rumus pendapatan. Hasil penelitian menunjukkan bahwa Pendapatan rata-rata petani padi rawa lebak dengan sistem surjan di Desa Tebing Gerinting Utara sebesar Rp6.752.278 per Ha/Mt.
Analisis Faktor Makro Ekonomi dan Faktor Internal Rasio Keuangan Terhadap Harga Saham Indeks LQ-45 yang Terdaftar di Bursa Efek Indonesia (Bei) Periode 2018-2022
Authors: Sarah Siti , Dasman H. Sunita
Published: July 2023

Penelitian ini memuat tentang pembahasan Analisis Faktor Makro Ekonomi Dan Faktor Internal Rasio Keuangan Terhadap Harga Saham Indeks LQ45 yang Terdaftar Di Bursa Efek Indonesia (BEI) periode 2018-2022. LQ45 merupakan salah satu indeks yang menggambarkan kelompok saham dari beberapa perusahaan yang menjadi perhatian investor untuk melakukan investasi. Pada penelitian ini terdapat 5 variabel independen yaitu Inflasi dan Suku Bunga yang menjadi bagian dari faktor Makro Ekonomi sedangkan faktor internal rasio keuangan yang diproksikan dengan Return On Assets (ROA) sebagai rasio profitabilitas dan Debt to Equity Ratio (DER) sebagai rasio solvabilitas dan Price to Book Value (PBV). Adanya penelitian ini yaitu untuk mencari data, informasi serta mengetahui pengaruh 5 variabel independen terhadap variabel dependent. Populasi pada penelitian ini yaitu perusahaan pada indeks LQ45 yang terdaftar di Bursa Efek Indonesia. Metode pengambilan sampel yang digunakan adalah metode purposive sampling dan diperoleh sampel sebanyak 17 perusahaan. Data yang digunakan yaitu data sekunder dari laporan keuangan dan harga saham perusahaan dan diolah menggunakan Eviews 9. Hasil penelitian ini menunjukkan bahwa secara persial variabel Inflasi tidak berpengaruh positif dan tidak signifikan, Suku Bunga tidak berpengaruh positif dan tidak signifikan, ROA berpengaruh positif dan tidak signifikan dengan presentase yang lemah, DER berpengaruh negatif dan signifikan dan PBV berpengaruh positif dan signifikan terhadap Harga Saham indeks LQ45.
Karakteristik Dewan Komisaris, Tanggung Jawab Sosial Perusahaan, dan Kinerja Keuangan Perusahaan
Authors: Aris Mattunruang Andi , Wulandari R Reski
Published: July 2023

Tujuan dari penelitian ini dilakukan untuk mengetahui apakah tanggung jawab sosial perusahaan dipengaruhi oleh karakteristik dewan komisaris (jumlah komisaris independen, keragaman dewan komisaris, dan konsentrasi kepemilikan) dan apakah kinerja keuangan (ROA, ROE dan Tobin’s Q) dipengaruhi oleh tanggung jawab sosial perusahaan, pada perusahaan yang terdaftar pada Bursa Efek Indonesia pada periode 2015 sampai dengan 2019. Populasi yang digunakan adalah seluruh perusahaan yang terdaftar dalam Bursa Efek Indonesia selama lima tahun berturut-turut. Metode pengambilan sampel dipilih menggunakan purposive sampling yaitu perusahaan non keuangan yang terdapat dalam Kompas 100 dan Pefindo 25. Penelitian ini menggunakan pendekatan kuantitatif. Pengambilan sampel yang digunakan dalam penelitian ini 66 perusahaan dengan 330 observasi. Metode analisis data menggunakan regresi data panel (Eviews 9) dengan Uji Statistik Deskriptif, Uji Kesesuaian Model yaitu chow test dan hausman test, dilanjutkan dengan Uji F, Uji Goodness of Fit, Uji hipotesis, dan terakhir adalah Uji t. Hasil penelitian menunjukan bahwa jumlah komisaris independen, keragaman dewan komisaris berpengaruh positif signifikan terhadap tanggung jawab sosial perusahaan. Namun, konsentrasi kepemilikan berpengaruh positif namun hipotesis tidak terdukung sedangkan tanggung jawab sosial perusahaan berpengaruh positif dan signifikan terhadap ROA, ROE dan Tobin’s Q. Namun, variabel kontrol jumlah dewan komisaris, size dan leverage tidak berpengaruh signifikan terhadap tanggung jawab sosial maupun kinerja keuangan perusahaan.
Analisis Minat Berwirausaha Masyarakat Daerah Istimewa Yogyakarta
Authors: Syafwan Lysander Mohammad Ahyar , Prawita Dika , Azwar Azwar
Published: July 2023

Upaya menumbuhkan minat berwirausaha dikalangan masyarakat masyarakat merupakan salah satu bentuk keberhasilan pemerintah D.I Yogyakarta dalam upaya membantu pemerintah pusat untuk mengurangi pengangguran. Kreativitas dan inovasi merupakan modal awal dalam menumbuhkan minat berwirausaha. Minat wirausaha ini dipengaruhi oleh beberapa faktor diantaranya kepribadian wirausaha, pengetahuan wirausaha, keterampilan wirausaha dan faktor lingkungan. Penelitian ini bertujuan untuk menganalisis pengaruh kepribadian wirausaha, pengetahuan wirausaha, keterampilan wirausaha terhadap minat wirausaha masyarakat melalui lingkungan. Metode penelitian ini menggunakan pendekatan kuantitatif. Subyek dalam penelitian yaitu masyarakat Daerah Istimewa Yogyakarta dengan populasi 3,689 juta (2020) responden, sampel diperoleh dengan teknik accidental sampling sebanyak 100 responden. Metode pengumpulan data menggunakan kuesioner. Analisis data menggunakan smart PLS dan analisis jalur (path analysis). Hasil analisis data menunjukan variabel kepribadian wirausaha, pengetahuan wirausaha, keterampilan wirausaha berpengaruh terhadap minat wirausaha dan melalui faktor lingkungan.
Review on Stem Cell Therapy and its Various Aspects
Authors: G. Dhakad Ganesh , O. Fate Bhagyashri , R. Pandav Amruta , V. Shrirao Abhijit , Kochar N. I. , Chandewar A. V.
Published: July 2023

Stem cells have the ability to differentiate into specific cell types. The two defining characteristics of a stem cell are perpetual self-renewal and the ability to differentiate into a specialized adult cell type. There are two major classes of stem cells: pluripotent that can become any cell in the adult body, and multipotent that are restricted to becoming a more limited population of cells. Cell sources, characteristics, differentiation and therapeutic applications are discussed. Stem cells have great potential in tissue regeneration and repair but much still needs to be learned about their biology, manipulation and safety before their full therapeutic potential can be achieved.
Exploring the Diagnostic Potential of IHC and Next-Generation Sequencing Approaches for Endometrial Carcinoma Detection and Classification
Authors: ALI Azhin Saber , ALALEM Lana Sardar
Published: July 2023

Background: Globally, in 2018 endometrial cancer (EC) regarded as the sixth most commonly diagnosed cancer and the fourteenth leading cause of cancer with more deaths in females. Nowadays classical and modern classifications can be performing for diagnosing various types of cancers including endometrial cancer. Based on this our Objective of study is to determine the effectiveness of immunohistochemical observation, a quick and easy method for determining MSI and/or other types of EC which based on modern classification. As molecular study takes more cost we want to compare the both methods and showing the possibility of doing IHC instead of molecular study. Methods: This study designed to establish a small gene panel of Next Generation Sequencing NGS of endometrial cancer patients targeting 12 genes; MSH6, MLH3, MSH3, CDH1, PTEN, MSH2, MLH1, PMS2, FGFR2, BRCA1, MUTYH and AREL1. By using DNBSEQ-G400 Platform, Human Core Exome kit and Python software for analysis is used. At the same time, Dako kit used to performing IHC for six primary antibodies used to detect each of MSH6, MSH2, MLH, PMS2, PTEN and CDH1. The primary antibodies were applied on 5 µm formalin- fixed paraffin- embedded (FFPE). Results; histopathological examinations showed that all patients were at stage II endometrioid endometrial carcinoma. The FIGO classification were Ia and Ib. Microsatellite instability (MSI), nuclear staining immunoreaction for PTEN antibodies and membranous E- cadherin immunoreactions observed through IHC study. The molecular studies detected several polymorphisms which have clinical significant and some of them have conflict interpretations. Conclusions; we considered that, simply immunoreaction staining procedure can be use as alternative method for MSI phenotype detection rather than any type of more expensive and complex method of NGS. Concerning PTEN and ECAD1 antibodies reactions, also could be dependable in diagnosis and treatment and performing them if molecular diagnosis not available.
Cases of 193 Inpatients and Caregivers with COVID-19 Negative Conversion Positive— A Single-Center Analysis
Authors: Yang Chuang , Ouzhu Luobu , Hao Caihong , Ning Enya
Published: July 2023

Background: A sudden outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the Tibetan Autonomous Region in August 2022 disrupted the coronavirus disease 2019 (COVID-19)-free status of the Tibetan over the past 3 years and poses severe risks to public health. Methods: A total of 2966 patients and caregivers were admitted to our hospital from August 01, 2022 to October 10, 2022 and cases of negative-to-positive conversion were analyzed during hospitalization. Results: In total, 193 cases of negative-to-positive conversion were identified. The rates of hospitalization for adults (age, ≥15 years), children (age, 0–14 years), and caregivers were 4.04%, 3.07%, and 5.94%, respectively. For the majority of COVID-19 cases, negative-to-positive conversion occurred within 1–4 days. The rates of cases with mild, moderate, and severe symptoms were 41.45%, 46.63%, and 11.92%, respectively. The Tibetan population accounted for 86.01% of all positive cases. Conclusion: Mutant variants of SARS-CoV-2 can adapt to harsh conditions at high altitudes and spread among local populations, suggesting that infection prevention and control efforts should be continued in some regions to protect public health.
A Hybrid Firefly with Dynamic Multi-swarm Particle Swarm Optimization for WSN Deployment
Authors: Wei-Yan Chang Wei-Yan Chang , Wei-Yan Chang Prathibha Soma , Prathibha Soma Huan Chen , Huan Chen Hsuan Chang , Hsuan Chang Chun-Wei Tsai
Published: July 2023

Enhancing the coverage area of the sensing range with the limiting resource is a critical problem in the wireless sensor network (WSN). Mobile sensors are patched coverage holes and they also have limited energy to move in large distances. Several recent studies indicated the metaheuristic algorithms can find an acceptable deployed solution in a reasonable time, especially the PSO-based algorithm. However, the speeds of convergence of most PSO-based algorithms are too fast which will lead to the premature problem to degrade the quality of deployed performance in WSN. A hybrid metaheuristic combined with dynamic multi-swarm particle swarm optimization and firefly algorithm will be presented in this paper to find an acceptable deployed solution with the maximum coverage rate and minimum energy consumption via static and mobile sensors. Moreover, a novel switch search mechanism between sub-swarms will also be presented for the proposed algorithm to avoid fall into local optimal in early convergence process. The simulation results show that the proposed method can obtain better solutions than other PSO-based deployment algorithms compared in this paper in terms of coverage rate and energy consumption.

 