bluuebunny/crossref_metadata_2025 huggingface dataset:
Aerobic Exercise Performance and Muscle Strength in Statin Users—The LIFESTAT Study
Authors: MORVILLE THOMAS , DOHLMANN TINE LOVSØ , KUHLMAN ANJA BIRK , SAHL RONNI EG , KRIEGBAUM MARGIT , LARSEN STEEN , DELA FLEMMING , HELGE JØRN WULFF
Published: February 2019

Introduction

Statins are widely used in both primary and secondary prevention of cardiovascular disease. The treatment increases the risk of muscle pain (myalgia) which can affect muscle function and levels of physical activity. We investigated whether statin-associated myalgia is coupled to impaired aerobic exercise performance including fat oxidation as well as impaired muscle strength.

Methods

A population-based survey (6000 people) was performed to assess the prevalence of statin-associated myalgia in the Danish population. In addition, 64 statin users in primary prevention with myalgia (M; n = 25; 61 ± 1 yr) or without myalgia (NM; n = 37; 63 ± 1 yr) as well as a control group not taking statins (C; n = 20; 60 ± 2 yr) were enrolled in a cross-sectional study where they performed aerobic exercise and muscle strength tests.

Results

The response rate for the survey was 51% and data showed a prevalence of statin-associated myalgia in 19% of responders using statins. The experimental study showed no difference between the groups in aerobic capacity (C, 29 ± 1 mL O2·min−1·kg−1; M, 27 ± 1 mL O2·min−1·kg−1; NM, 28 ± 1 mL O2·min−1·kg−1) or maximal fat oxidation (C, 247 ± 26 mg·min−1; M, 295 ± 24 mg·min−1; NM, 279 ± 17 mg·min−1). Measurements of strength were similar in all three groups including rate of force development (C, 795 ± 56 N·m·s−1; M, 930 ± 93 N·m·s−1; NM, 971 ± 57 N·m·s−1) and leg extension power (C: 2.6 ± 0.2; M: 2.3 ± 0.1; NM: 2.4 ± 0.1 W·kg−1). All results are mean ± SEM.

Conclusion

Statin users in primary prevention experiencing myalgia do not have impaired aerobic exercise performance or muscle strength compared to nonmyalgic statin users or control subjects.
Rapid spread of double East- and West-African kdr mutations in wild Anopheles coluzzi from Côte d’Ivoire
Authors: Mouhamadou Chouaïbou Seïdou , N’Dri Prisca Bédjou , Fodjo Behi Kouadio , Sadia Christabelle Gba , Affoue France-Paraudie Kouadio , Koudou Benjamin Guibehi
Published: February 2019

Malaria morbidity and mortality rates in Sub-Saharan Africa are increasing. The scale-up of long-lasting insecticidal nets and indoor residual spraying have been the major contributors to the decrease of malaria burden. These tools are now threatened by insecticide resistance in malaria vectors, which is spreading dramatically. After two different real-time polymerase chain reaction molecular characterizations carried out on 70 mosquitoes sampled in the locality of Elibou in southern Côte d’Ivoire, results revealed that 9 mosquitoes from Anopheles coluzzi harbored the double East- and West-African knockdown resistance mutations. In the previous year, only 1 mosquito out of 150 sampled from 10 regions of the country had the same genotype. These results show the rapid spread of insecticide resistance in malaria vectors and highlight the urgent need to diversify the methods of vector control in order to avoid the failure of insecticide-based vector control tools which may favor malaria fatalities.
Performance Feedback in Hierarchical Business Groups: The Cross-Level Effects of Cognitive Accessibility on R&D Search Behavior
Authors: Rhee Luke , Ocasio William , Kim Tae-Hyun
Published: February 2019

This study examines the cross-level effect of group-level managers on member firms’ problemistic search in hierarchical business groups. Using multilevel data from Korean business groups, we propose that the effects of failure to meet an aspiration level on R&D search intensity increase when member firm performance and R&D investments are more cognitively accessible to group-level managers. Specifically, we find, first, that when underperforming firms are widespread in a business group, a focal member firm intensifies R&D search in response to performance below an aspiration level because member firm performance, as a group-level problem, becomes cognitively accessible to group-level managers. Second, as member firms operating in R&D intensive industries are more prevalent in a business group, R&D investments, as a search solution, become more cognitively accessible to group-level managers. Thus, a focal member firm reinforces R&D search in response to the performance shortfall. We discuss the implications of these findings for research on the behavioral theory of the firm and performance feedback.
Does the Middle Conform or Compete? Quality Thresholds Predict the Locus of Innovation
Authors: Vashevko Anthony
Published: February 2019

Where does innovation come from? This research models producer incentives to innovate with a focus on the role of audiences in constructing quality thresholds within markets. Market audiences create mechanisms for identifying the highest-quality producers in a market. I highlight a key distinction between fixed quality thresholds (such as accreditations) and quality thresholds that respond to producer quality (such as rankings or best-of-breed awards). Producers evaluate how the inherently risky nature of innovation interacts with these thresholds. The model predicts conditions under which innovation emerges from the best producers in a market, from producers near the threshold in a market, from both, or from nowhere. Such predictions generalize and simplify several existing organizational theories of innovation.

The online appendix is available at https://doi.org/10.1287/orsc.2018.1240 .
The body’s civil war: Understanding autoimmune conditions
Authors: Greener Mark
Published: February 2019

Mark Greener details the genesis of some of the most common autoimmune diseases
Genetic biases related to chronic venous ulceration
Authors: Stana Jan , Maver Uroš , Potočnik Uroš
Published: February 2019

Chronic wounds represent a major socioeconomic problem. Chronic venous ulceration is one of the least well-understood types of chronic wounds. A chronic venous ulcer arises as a result of chronic venous insufficiency (CVI), which affects approximately 10–35% of people in the developed world, yet not all people with CVI develop ulceration. The question of why some patients with CVI develop chronic ulceration and others do not, still remains unanswered. Risk factors for the development of chronic ulceration are poorly understood and include age, residual iliofemoral vein obstruction, residual deep incompetence, persistent venous hypertension, obesity and genetics. The genetic aspects of CVI have only been vaguely evaluated. This paper reports on a literature review of the variation in genetic polymorphisms and gene expression associated with the development of a chronic venous ulceration.
Hair raising!
Authors: Hart Karen
Published: February 2019

Whether children have experienced a visit to the hairdresser, or had their hair cut at home, they will all enjoy hairdresser role-play. Through this they will grasp the practical and social sides of the role.
Imaginative leaps
Authors: Clarke Jenni
Published: February 2019

Physical development and imaginative play go naturally together and there are lots of ways you can resource the environment to ensure that children can be active within their own creative worlds.
Animal empathy
Authors: Harries Judith
Published: February 2019

Martin Wardell's books, including the best-selling Owl Babies, are perfect for helping children to explore their feelings. Use them to tap into their ideas about what is fair and unfair.
Mum's special day
Authors: Hewson Claire
Published: February 2019

Celebrating Mother's Day is a great way to encourage children to talk about their mothers and exercise their literacy skills as they make cards and learn to write simple, loving messsages.
Euskal gramatika zaharren katalogo baterantz: gramatika eskuizkribatuak / Towards a catalog of ancient Basque grammars: handwritten grammars
Authors: Gómez-López Ricardo
Published: February 2019

Ekarpen honen helburua XX. mendearen aurretik eskuz idatzitako euskal gramatiken zerrenda eta deskribapena egitea da. Sarrera baten ondoren (§ 1), gaingiroki aurkeztuko ditut, batetik, gramatika eskuizkribatu galduak (§ 2) eta, bestetik, eskuizkribua gordetzeaz gain, bere garaian inprimatu zirenak edo berrikiago argitaratu direnak ere (§ 3). Ondoren, xehekiago begiratuko diet eskuizkribuetan soilik gorde zaizkigun euskal gramatika zahar osoei (§ 4).
Asimetrías gramaticales asociadas a la animacidad en la lengua vasca: una perspectiva tipológica / Animacy-based grammatical asymmetries in Basque: a typological perspective
Authors: Igartua Iván , Santazilia Ekaitz
Published: February 2019

This study provides a typological analysis of two phenomena related to case-marking in Basque. In both of them, animacy —or the distinction between what is animate and what is not— turns out to be determinant: we discuss case assignment to direct objects, on the one hand, and marking of locative cases, on the other hand. We have compared the two phenomena with diverse typological parallels in order to account for the variety of possible morphological strategies and identify particular conditions and restrictions. Furthermore, we have argued that differential object marking in Basque is a recent phenomenon, induced by language contact, whereas differential locative marking has an intralinguistic nature. Finally, we have defended that the role of animacy in both types of differential marking is different: in the first example it conditions case assignment and in the second it operates as a grammatical gender.
Vasconia en el siglo XII: Roger de Howden, el "De Viis Maris" y la extensión del vizcondado de Bayona / Vasconia in the XII Century: Roger de Howden, "De viis maris" and the expanse of the viscounty of Bayonne
Authors: Ruiz Arzalluz Íñigo
Published: February 2019

De viis maris, a text that remained unknown until the edition published by Gautier Dalché in 2005, is a maritime itinerary composed about 1191-1193 and ascribed to the English historian Roger de Howden, who provides some data related to the Vasconia of that time and, particularly, about the expanse of the viscounty of Bayonne. An insufficient information on this subject was present also in the Chronica by the same Howden: the work, printed in 1596 and 1601, was known to Oihenart, who included the detail in his Notitia utriusque Vasconiae and drew erroneous conclusions that gave rise to controversy in the Basque historiography through the subsequent centuries and that have occasionally survived until today.
Zer da lehenago, aditzoina ala partizipioa? Oharrak euskararen kronologiarako / Which came first: the verb root or the participle? Notes for the chronology of Basque
Authors: Urgell Blanca
Published: February 2019

Lan honetan aditzoinaren eta partizipioaren arteko erlazioaren historian sakondu nahi dut. Datuen bidez ikusiko dugu beren arteko oposaketak diakronikoki ñabardura gehiago dituela sinkronikoki ematen duena baino eta, funtsean, euskara historikoan dakusguna ezin dela aitzineuskarara eraman bere horretan. Ildo honetatik, hipotesi indartsuago bat jarriko dut frogapean, alegia, aditzoin historikoa jatorriz Erdi Aroko lehen lekukotasunak baino lehen elkartu-eratorrien lotunean eragina izan zuten hots-aldaketa arau ezagunek sortutako irregulartasunen morfologizatzearen ondorio dela. Hipotesi honek, lehen azaldu gabe zeuden zenbait fenomeno (Trask-en *emanite erako aditz-izenak, adibidez) azaltzeaz gainera, aditz sistema historikoaren eraketarekin lotutako beste fenomeno batzuen sorreraz, izaeraz edota kronologiaz ere aurrerapenak egiteko aukera ematen digu, hala nola perfektuzko perifrasiez eta -itu partizipio pleonastikoez.
Catastrophic Antiphospholipid Syndrome Presenting as Congestive Heart Failure in a Patient with Thrombotic Microangiopathy
Authors: Tulai Iulia M. , Penciu Oana M. , Raut Raymond , Rudinskaya Alla
Published: February 2019

Thrombotic microangiopathic syndromes are characterized by thrombus formation leading to microangiopathic hemolytic anemia, thrombocytopenia, and end-organ injury that most often affects the kidney and brain. Patients with thrombotic microangiopathy can also present with cardiac involvement, which has been shown to worsen their prognosis. We describe the case of a 46-year-old woman who presented with acute congestive heart failure as a manifestation of catastrophic antiphospholipid syndrome, which is characterized by rapidly progressing multiorgan involvement. Targeted therapy improved our patient's cardiomyopathy and saved her life. Increased recognition of thrombotic microangiopathy as an underlying pathophysiologic mechanism in heart failure and initiation of timely treatment may help to prevent death in patients with thrombotic microangiopathy.
Developing Educative Snake and Ladder Learning Media to Improve Understanding on Living Creature Concept
Authors: Agustina Winarti , . Hapidin , Tarwiyah Tuti
Published: February 2019

Purpose of this research is to develop educative snake and ladder learning media to improve the understanding on concept of living creature on early childhood. The research was conducted in Bekasi municipality with R and D method. The results
indicate that in aspects of (1) availability of learning media: 75% of teachers used the learning media optimally and 67% of teachers perceived that the learning media made available by the school was less supportive to the learning:(2) requirement:
only 25% of teachers who used the game media in learning and 83% of teachers recognized that the learning material in theme books was very supportive to use the media;(3) process: 83% of teachers had difficulty to present the learning material due to
children characteristics which are active and aggressive and 75% of teachers recognized that the children’s understanding level regarding the media presented was still low; expectation: 92% of teachers supported the making of educative snake and
ladder learning media. Tests administered to the students regarding the living creative concept obtained average score 53,44, which means “insufficient.”
The Influence of the Realistic Mathematics Education Approach and Early Mathematical Ability to Mathematical Literacy
Authors: Sutisna Andi Permana , Budi Agus Setyo , Noornia Anton
Published: February 2019

This research is based on the low level of Indonesian students mathematical literacy test released by PISA in 2015. The purpose of this research is to examine the influence of Realistic Mathematics Education Approach and the earlymathematical
ability to mathematical literacy in statistical materials. This research uses group design by level 2 x 2. This study was conducted in students of class VIII. The result of this research shows that there is influence of Realistic Mathematics
Education Approach and early mathematical ability to mathematical literacy on statistical matter. Beside that, the Realistic Mathematics Education Approach not only increases mathematical literacy in students with high early mathematical skills, but
also in students with low early mathematical abilities.
Improvement of Ability of Calculation of Children Age 4-5 Years through Playing Puzzle
Authors: . Mumun , . Yetti , . Yufiarti
Published: February 2019

The study aims to improve the early counting ability of children aged four, five years in PAUD Jump by using the puzzle. Counting beginning is a fundamental ability for children to know the concept of numbers. The method used is action
research on students group B of 15 children through four stages of planning, action, observation, and reflection. Data are analyzed by qualitative and quantitative descriptive. Results of the study concluded that by using the Puzzle plannel, the
students' early numeracy skills could be improved. Student Ability increased from 44.66% before action and increased on first cycle about 49.25% and in the second cycle becomes 90.16%. Student's ability is high enough at a game process that uses
puzzles, ice cream sticks and buttons clasped in planel
Utilization of Demonstration Methods as Sex Education in Early Childhood
Authors: Kristiana Seconingsih , Jamaris Martini , Sumantri M.Syarif
Published: February 2019

The purpose of this study is to determine the increase in sex behavior through sex education in children aged 6 - 7 years based on demonstration method. The research was conducted at Santa Theresia Depok Elementary School. Implementation of
this research starts from November to December 2017 with 25 students as research subjects and two observers. The method used in this research is action research with reference to the action research model of Kemmis and Taggart, where the activity of
one cycle consists of 4 components, including planning, action, observation, and reflection. This study consists of 1 cycle consisting of 8 actions. Data analysis is conducted by using action research. Qualitative data were obtained through
observations during the implementation of action interventions through field notes, whereas the quantitative data were obtained by comparing the average score of the initial assessment result (before the action was given) and the final assessment
(after the action was given).The results showed an increase in the formation of sex behavior through sex education in children aged 6 - 7 years based on demonstration method in which the average score of 65.8% increased to 89.1%. It means that there
has been a significant increase from pre to post research. Implications that can be made to this demonstration method approach to be successful are: a) the teacher boldly explains, b) the teacher uses several examples, c) it uses simple, interesting,
and real media for students.
Mechanical Behaviour of Cement Concrete using Fibres
Authors: Vats Gaurav , Kuhar Preeti , Kumar Sanjeev
Published: February 2019

Concrete is the most used material for the construction in the modern time of infrastructures. Concrete is strong in compression but it is weak in tension and shear. To minimise those problems, fibres were introduced in concrete to enhance
its tensile strength and shear strength. In my present investigation, the mechanical properties of fibres reinforced concrete are studied by using steel fibre, glass fibre and polyamide fibre with a different weight fraction of fibres with respect to
cement. The mix design of M25 concrete with W/C ratio of 0.42 is prepared and total thirteen mixes included one control mix was prepared and tested in the laboratory. The total quantity of fibres mixed in the concrete are in order of 0%, 0.75%, 1.5%,
and 2.25% by weight of cement and one mix contains 0.33% of glass fibre, 0.33% of steel fibre and 0.33% of polyamide. The study shows that the mixed fibres provide better properties in controlling cracks and high strengths than single fibre and
concrete without fibre. On increasing the percentage of fibres beyond 1.5%, the strength of the concrete matrix decrease due to mat form of fibres or non-uniform distribution of fibres and also decrease due to non-cohesiveness of the concrete
particle to each other.
Learning Model Based on Multiple Representation to Increase Memorize Ability of Short Letter of Al Qur'an
Authors: Chalid T.Nurbani , Handini Myrnawati Crie , Yetti Elindra
Published: February 2019

The purpose of this study is to produc a learning model to memorize the Qur'an which corresponds to the stage of development and learning styles of children. The ability to memorize the Qur'an is marked marked by ability to recognize namely
ability to verify and to match and the ability to remember namely the ability to corespond dan ability to retrieving orally. The method used in this research is research and development, modification of research model by Borg and Gall and Dick and
Carrey. The data were collected by observation technique, questionnaire, interview, expert assessment instrument and field note. Quantitative data from the questionnaire results were analyzed using descriptive analysis technique with percentage,
while the test result data (pretest and posttest) the ability to memorize Al-Qur'an was analyzed by t test (t-test) using SPSS program. The result of paired sample t test in the experimental class shows 0.000 less than 0,05 so there is difference
before and after applied model. While the result of t test in control class showed value 0,423 and gt; 0,05 so there is no significant difference before and after applied model. The result of independent sample t test shows 0.000 so p value less than
0,05 and it can be concluded that there is a significant difference between the control class and the experimental class.
Influence of Career Self-Efficacy on Career Exploration among Senior High School Students in Relation to Gender
Authors: Brew Mavis , Ngman-Wara Ernest I. D.
Published: February 2019

The study sought to identify the various ways through which senior high school students in the Effutu Municipality explore existing careers. Also, the study sought to find out gender differences in career exploration level and career
selfefficacy levels among students. Survey research design was used for the study. Data for the study were collected from 273 (145 male and 128 female) senior high school students, selected from three mixed schools. Two questionnaires were developed
for the study to seek information on career exploration practices, students’ career exploration level, and career self-efficacy level. Descriptive and correlational statistics were used to analyse the data. Respondents’ scores on questionnaire were
organized descriptively into frequency counts and percentages. The results of the descriptive analysis showed that the main career exploration practice the students engaged in was field trip. Results of correlational statistics indicated that female
and male students had a higher career exploration level and higher career self-efficacy level respectively. The study concluded that the students were not exposed to other exploration practices to enable them settle on appropriate career choices. It
was recommended that school counsellors should consider other practices that involve when designing career exploration programmes to assist students explore existing careers.
Relationship between Parenting, Family Income, Nutritional Status and Gross Motor Skills of Children
Authors: . Zulkarnaena , . Yufiartib , Akhadiah Sabarti
Published: February 2019

The purpose of this study was to analyze the relationship between parenting, family income, nutritional status and gross motor skills of children age 5 to 6 years. This study was conducted in the Kindergarten of Sub-District of East Praya
Central Lombok Regency, West Nusa Tenggara, Indonesia. This research uses a quantitative approach with multiple correlation research method. Ninety-seven children were selected randomly using simple random sampling. The results of this study indicate
that parenting, family income and nutritional status associated simultaneously and significant with gross Motor skills. The total influence of 71.8% gross motor skills variable is explained by parenting, family income, and nutritional status. It can
be concluded that better parenting accompanied by a high family income and good nutritional status it can be ascertained gross motor skills will also be better
Construction and stability of type I blowup solutions for non-variational semilinear parabolic systems
Authors: Ghoul Tej-Eddine , Nguyen Van Tien , Zaag Hatem
Published: February 2019

In this note, we consider the semilinear heat system

\partial_{t}u=\Delta u+f(v),\quad\partial_{t}v=\mu\Delta v+g(u),\quad\mu>0,

where the nonlinearity has no gradient structure taking of the particular form

f(v)=v\lvert v\rvert^{p-1}\quad\text{and}\quad g(u)=u\lvert u\rvert^{q-1}\quad%
\text{with }p,q>1,

or

f(v)=e^{pv}\quad\text{and}\quad g(u)=e^{qu}\quad\text{with }p,q>0.

We exhibit type I blowup solutions for this system and give a precise description of its blowup profiles. The method relies on a two-step procedure: the reduction of the problem to a finite-dimensional one via a spectral analysis, and then solving the finite-dimensional problem by a classical topological argument based on index theory. As a consequence of our technique, the constructed solutions are stable under a small perturbation of initial data. The results and the main arguments presented in this note can be found in our papers
[T.-E. Ghoul, V. T. Nguyen and H. Zaag,
Construction and stability of blowup solutions for a non-variational semilinear parabolic system,
Ann. Inst. H. Poincaré Anal. Non Linéaire 35 2018, 6, 1577–1630] and
[M. A. Herrero and J. J. L. Velázquez,
Generic behaviour of one-dimensional blow up patterns,
Ann. Sc. Norm. Super. Pisa Cl. Sci. (4) 19 1992, 3, 381–450].
Equal-Order Stabilized Finite Element Approximation of the p-Stokes Equations on Anisotropic Cartesian Meshes
Authors: Ahlkrona Josefin , Braack Malte
Published: February 2019

The p-Stokes equations with power-law exponent

p
∈

(
1
,
2
)

{p\in(1,2)}

describes non-Newtonian, shear-thinning, incompressible flow. In many industrial applications and natural settings, shear-thinning flow takes place in very thin domains. To account for such anisotropic domains in simulations,
we here study an equal-order bi-linear anisotropic finite element discretization of the p-Stokes equations, and extend a non-linear Local Projection Stabilization to anisotropic meshes. We prove an a priori estimate and illustrate the results with two numerical examples, one confirming the rate of convergence predicted by the a-priori analysis, and one showing the advantages of an anisotropic stabilization compared to an isotropic one.
Analysis of the Influence of Transmission Resources Control in Tree Structure Networks
Authors: Bujnowski Sławomir , Marciniak Tomasz , Marciniak Beata , Lutowski Zbigniew , Marchewka Adam
Published: February 2019

The aim of the paper is to draw attention to the possibility of improving the transmission properties of telecommunication networks by subordinating the capacity of individual links to the frequency of their occurrence in a set of minimum length paths. The defined unevenness coefficient was used to divide the global transmission resources of the network in order to make the traffic carried by this network as large as possible. The article presents the results of the simulation tests to which tree topology network was subjected.
Design of a Telemedical Vest for Sleep Disorder Diagnosis - A Preliminary Analysis
Authors: Drzazga Jakub Bogdan
Published: February 2019

This paper presents the components of a sleep apnea analysis device that have been evaluated for diagnosis suitability and expected difficulties. The medical background and statistics of sleep apnea are presented. Work related to the topic is then discussed. A description of the system components follows: ECG, respiratory effort, nasal flow and pulse oximetry. Problems expected with all of these measurements are then outlined both from the methodological and electronic perspective. The main difficulties identified are the necessity to maintain the exact location of the sensors on the patient’s body and vulnerability of the sensors to variations of the environmental conditions. Challenges on the electronic aspect are then discussed, which are mainly caused by the need of measuring small signals (noise, interference) and compensation of the sensors’ nonlinearity. Power supply design in the context of the measurement accuracy is also considered followed by an evaluation of the impact of telemedical function presence. The paper ends with a summary and conclusions.
Learning solutions to the source inverse problem of wave equations using LS-SVM
Authors: Wu Ziku , Ding Chang , Li Guofeng , Han Xiaoming , Li Juan
Published: February 2019

A method based on least squares support vector machines (LS-SVM) is proposed to solve the source inverse problem of wave equations. Contrary to the most existing methods, the proposed method provides a closed form approximate solution which satisfies the boundary conditions and the initial conditions. The proposed method can recover the unknown source term with the given additional conditions. Furthermore, it has reasonable robustness to noise. Numerical results show the proposed method can be used to solve the source inverse problem of wave equations.
Exact information ratios for secret sharing on small graphs with girth at least 5
Authors: Harsányi Károly , Ligeti Péter
Published: February 2019

In a secret-sharing scheme, a piece of information – the secret – is distributed among a finite set of participants in such a way that only some predefined coalitions can recover it.
The efficiency of the scheme is measured by the amount of information the most heavily loaded participant must remember.
This amount is called information ratio, and one of the most interesting problems of this topic is to calculate the exact information ratio of given structures.
In this paper, the information ratios of all but one graph-based schemes on 8 or 9 vertices with a girth at least 5 and all graph-based schemes on 10 vertices and 10 edges with a girth at least 5 are determined using two polyhedral combinatoric tools: the entropy method and covering with stars.
Beyond the investigation of new graphs, the paper contains a few improvements and corrections of recent results on graphs with 9 vertices.
Furthermore, we determine the exact information ratio of a large class of generalized sunlet graphs consisting of some pendant paths attached to a cycle of length at least 5.
Genetic variability in Peregrine Falcon populations of the Western Palaearctic region
Authors: Mengoni Chiara , Zuberogoitia Iñigo , Mucci Nadia , Boano Giovanni , Urban Tomáš , Guzzo Enrico , Sarà Maurizio
Published: February 2019

We analysed variation in ten polymorphic microsatellite loci and a portion of cytochrome b gene of mitochondrial DNA in 65 samples from four populations of Peregrine Falcon (Falco peregrinus peregrinus and F. p. brookei) breeding in Northern and Southern Italy, Northern Spain and the Czech Republic to assess genetic diversity in the poorly investigated Western Palearctic region. We added to our cytochrome b sequences a dataset of previously published mtDNA sequences of other populations and subspecies to outline genetic variation in the region on a worldwide basis. Regarding mtDNA we identified 12 haplotypes from our 65 Peregrine Falcon samples, nine of which were new and three already known. The 52% of our samples, including all Italian and Czech specimens, belonged to the previously identified HI haplotype, another 22% of the samples, most of which were from Sicily, showed the new H1 haplotype, while the remaining 26% of the sample partitioned among the other 10 haplotypes. Allelic patterns and genetic structuring of microsatellites were similar to those of other European populations. Genetic differentiation in both mtDNA and microsatellites loci is almost absent and it is not possible to distinguish geographical groups according to taxonomic designation at the subspecies level.
Long-term monitoring of a successful recovery program of Peregrine Falcons in Virginia
Authors: Watts Bryan D. , Byrd Mitchell A. , Mojica Elizabeth K. , Padgett Shawn M. , Harding Sergio R. , Koppie Craig A.
Published: February 2019

The Peregrine Falcon(Falco peregrinus anatum)was believed to be extirpated as a breeding species in Virginia by the early 1960s. An aggressive restoration program was initiated in 1978 that involved the release of captive-reared birds totaling 115 on the Coastal Plain (1978–1985) and 127 in the Mountain physiographic region (1985–1993). The first occupied territory was established and the first breeding attempt was documented in 1979 and 1982, respectively. We have monitored the size, distribution, reproductive rate, and substrate use of the resulting breeding population (1979–2016). The population proceeded through an establishment phase (1979–1993) driven by releases with an average doubling time of 3.8 yrs to a consolidation phase (1994–2016) with an average doubling time of 23.1 yrs. The state supported 31 breeding pairs by 2016. Per capita reproductive rates have increased significantly over the study period from 0.89 (1979–1993) to 1.86 (1994–2016). Average nesting success increased from 67.1% to 82.7% over the same period. Nesting attempts (n = 469) have been documented on dedicated peregrine towers (52.1%), bridges (26.1%), buildings (4.1%), and various man-made structures (13.0%) with only 4.7% documented on natural cliffs. The population appears to be self-sustaining with reproductive rates exceeding 1.5 young/pair every year since 1999. An ongoing management concern is that only 8.9% of known territories (n = 45) identified since introductions and 4.7% of documented breeding attempts (n = 469) have occurred within the historic mountain breeding range.
Results of eighteen years (2000–2017) monitoring study of an extra-alpine Peregrine Falcon Falco peregrinus population in North-Western Italy
Authors: Beraudo Pier Luigi
Published: February 2019

The Author reports the results of a survey about a breeding extra-alpine Peregrine Falcon population in Cuneo Province, NW Italy. The first reproduction was recorded in 2000, and from that year, the monitoring work localized 16 occupied territories in an area of 1,900 km2 covering the hills and nearby lowland areas. The average distance between breeding territories was of 7.6 km with a density 0.7 pairs/100 km2. During the eighteen years, 89 successful breeding attempts were recorded, 81 of them led to fledging of 206 young. Average breeding success was 2.5 juv/reproducing pairs. The nests are located on bridges (motorway viaducts and rail way bridges) and clay/sandstone cliffs. Preliminary prey analyses showed that pigeons and doves represent the 75% of their diet.
Polyoxometalates in photocatalysis
Authors: Streb Carsten , Kastner Katharina , Tucher Johannes
Published: February 2019

Recent developments in polyoxometalate photochemistry are discussed with a focus on visible light driven productive chemical reactions. Special attention is given to the fundamental photochemistry of polyoxometalates and the effects on the
resulting photoprocesses.
Dynamics of brain connectivity after stroke
Authors: Desowska Adela , Turner Duncan L.
Published: February 2019

Recovery from a stroke is a dynamic time-dependent process, in which the central nervous system reorganises to accommodate for the impact of the injury. The purpose of this paper is to review recent longitudinal studies of changes in brain connectivity after stroke. A systematic review of research papers reporting functional or effective connectivity at two or more time points in stroke patients was conducted. Stroke leads to an early reduction of connectivity in the motor network. With recovery time, the connectivity increases and can reach the same levels as in healthy participants. The increase in connectivity is correlated with functional motor gains. A new, more randomised pattern of connectivity may then emerge in the longer term. In some instances, a pattern of increased connectivity even higher than in healthy controls can be observed, and is related either to a specific time point or to a specific neural structure. Rehabilitation interventions can help improve connectivity between specific regions. Moreover, motor network connectivity undergoes reorganisation during recovery from a stroke and can be related to behavioural recovery. A detailed analysis of changes in connectivity pattern may enable a better understanding of adaptation to a stroke and how compensatory mechanisms in the brain may be supported by rehabilitation.
Diagnóstico de la situación actual de una empresa de servicios de alimentación con respecto al cumplimiento de los requisitos de la norma ISO 9001:2015 para un sistema de gestión de la calidad
Authors: Parra Griselda María , De la Ossa José Julián , Ruiz Stephanie del Carmen
Published: February 2019

Hoy en día las empresas alrededor del mundo se encuentran en un entorno altamente competitivo donde los clientes son cada vez más exigentes y buscan productos o servicios cuya calidad les permita satisfacer plenamente sus requisitos. Por lo tanto, quienes quieran permanecer a largo plazo deben implementar estrategias que les permitan demostrar su capacidad de cumplir con las necesidades y expectativas de sus clientes y demás partes interesadas. El objetivo de este artículo es realizar el diagnóstico de la situación actual de una empresa de servicios de alimentación con respecto al cumplimiento de los requisitos de la norma ISO 9001:2015 para un sistema de gestión de la calidad. Para cumplir con el objetivo planteado, inicialmente se identificaron los requisitos de la norma, luego se diseñó una herramienta para evaluar el cumplimiento de la empresa con respecto a los requisitos identificados en la norma, se realizó una auditoría de la situación actual del sistema de gestión de calidad de la empresa objeto de estudio en relación con la norma y finalmente se presentó un informe de cumplimiento y planes de acción. Los resultados permitieron evidenciar que la empresa objeto de estudio tiene un cumplimiento bajo con respecto a la norma.
THE INFLUENCE OF VARIETY ON THE CONTENT OF TOTAL POLYPHENOLS AND ANTIOXIDANT ACTIVITY IN LEEK (ALLIUM PORRUM L.)
Authors: Kovarovič JÃ¡n , Bystrická Judita , Micová Marianna , Harangozo Ä½uboÅ¡ , Miššík Juraj , Hegedűsová AlÅ¾beta
Published: February 2019

Leek (Allium porrum L.) is a member of the Allium genus. It is known for its specific taste and aroma. Leek is used in gastronomy and modern food technologies. It is also important to note that bioactive substances of leek are very little explored. Compared to onion and garlic, little attention is paid to the leek. The samples of plant material were collected from the area of Zohor (Slovakia). The aim of this study was to analyse the content of total polyphenols (TPC) and the value antioxidant activity (AOA) in selected cultivars of leek. The samples of leek were homogenized and a methanolic extract was prepared. These extracts were used for analyses. Total polyphenol content in the samples ranged from 504.22 ± 48.28 mg GAE.kg-1 DW to 4767.71 ± 80.55 mg GAE.kg-1 DW. The values of antioxidant activity were from 4.30 ± 1.02 to 47.40 ± 0.49 % inhibition.
LUNASIN AND ITS VERSATILE HEALTH-PROMOTING ACTIONS
Authors: Ďúranová Hana , Fialková Veronika , Bilčíková Jana , Lukáč Norbert , Kňažická Zuzana
Published: February 2019

The present review focuses on the potential health benefits of lunasin reported to date. Epidemiological studies on human and animals have demonstrated lower incidence of various types of cancer and other chronic diseases related to consumption of diets containing high amounts of soybean products. Naturally present in soybean, lunasin is the most isolated bioactive peptide with 43 amino acid residues, some of them creating an RGD motif, chromatic-binding helical region and an aspartic acid tail. Due to the three multiple functional domains, the intriguing peptide serves as promising candidate in exerting many-sided health-beneficial actions, such as antioxidant capacity, anti-inflammatory, hypocholesterolemic, and anticancerous activities. Depending on the soybean genotype, the lunasin content in the crop varies from 0.5 - 8.1 mg/g of seed. Besides soybean, it has also been identified in wheat Solanum nigrum, rye, barley, amaranth seeds, triticale and quinoa. In the current review, the structure, bioavailability, and molecular mechanisms involved in health-promoting effects of lunasin have also been summarized.
A Telehealth-Enhanced Referral Process in Pediatric Primary Care: A Cluster Randomized Trial
Authors: Coker Tumaini R. , Porras-Javier Lorena , Zhang Lily , Soares Neelkamal , Park Christine , Patel Alpa , Tang Lingqi , Chung Paul J. , Zima Bonnie T.
Published: February 2019

OBJECTIVES:

To improve the mental health (MH) referral process for children referred from primary care to community mental health clinics (CMHCs) by using a community-partnered approach.

METHODS:

Our partners were a multisite federally qualified health center and 2 CMHCs in Los Angeles County. We randomly assigned 6 federally qualified health center clinics to the intervention or as a control and implemented a newly developed telehealth-enhanced referral process (video orientation to the CMHC and a live videoconference CMHC screening visit) for all MH referrals from the intervention clinics. Our primary outcome was CMHC access defined by completion of the initial access point for referral (CMHC screening visit). We used multivariate logistic and linear regression to examine intervention impact on our primary outcome. To accommodate the cluster design, we used mixed-effect regression models.

RESULTS:

A total of 342 children ages 5 to 12 were enrolled; 86.5% were Latino, 61.7% were boys, and the mean age at enrollment was 8.6 years. Children using the telehealth-enabled referral process had 3 times the odds of completing the initial CMHC screening visit compared with children who were referred by using usual care procedures (80.49% vs 64.04%; adjusted odds ratio 3.02 [95% confidence interval 1.47 to 6.22]). Among children who completed the CMHC screening visit, intervention participants took 6.6 days longer to achieve it but also reported greater satisfaction with the referral system compared with controls. Once this initial access point in referral was completed, >80% of eligible intervention and control participants (174 of 213) went on to an MH visit.

CONCLUSIONS:

A novel telehealth-enhanced referral process developed by using a community-partnered approach improved initial access to CMHCs for children referred from primary care.
Análisis de la vulnerabilidad geotécnica en las obras de ingeniería de la región niquelífera de Holguín a partir del empleo de métodos geodésicos
Authors: Acosta-González Luis Enrique , De Lacy-Pérez de Los Cobos M. Clara , Ricardo-Desdín Sergio Edilio , García-Díaz Jorge , Hernández-Cruz Osmany
Published: February 2019

En el trabajo se aborda la problemática del análisis de vulnerabilidad geotécnica en las obras industriales, con un nuevo enfoque sobre los modelos y terminologías en el análisis de la deformación. Se presenta una metodología para la determinación de los índices de vulnerabilidad geotécnica, a partir de la comparación de los valores de asentamientos determinadas por métodos geodésicos con las tolerancias fijadas por las normativas vigentes. Se realiza la validación de la metodología en cuatro casos de estudio de la región niquelífera de la provincia de Holguín: maquinarias industriales “Secaderos tubulares rotatorios”, depósitos de sustancias tóxicas “Base de amoniaco”, depósitos de sustancias inflamables “Tanque de combustible” y depósitos de mineral. Se demuestra la factibilidad de los resultados y la importancia de los estudios integrales de vulnerabilidad, a partir de la interacción de criterios concluyentes de varias disciplinas como la Geodesia, la Geofísica, la Geotecnia y la Ingeniería Civil.
Nota Corta: Publicando Programas Computacionales Aplicados a las Ciencias de la Tierra
Authors: Suarez-Burgoa Ludger O.
Published: February 2019

En la era de los grandes datos, el arte de crear un programa computacional aplicado para desarrollar un procedimiento de cálculo en las Ciencias de la Tierra se ha convertido en una habilidad más para el científico. La presente nota técnica corta comenta acerca de las mínimas reglas que se debe tomar presente para publicar código computacional aplicado a las Ciencias de la Tierra. Finalmente, el autor incentiva a todo geocientífico para que se convierta en un productor de códigos aplicados.
Complejidades de la estimación de recursos en yacimientos tipo Bechi en el noroeste de Pinar del Río, Cuba, usando Geoestadística no Lineal
Authors: Díaz-Carmona Abdiel , Cuador-Gil José Quintín
Published: February 2019

Se presenta la estimación de los contenidos de Cobre (Cu) en el yacimiento “Hierro Mantua” usando métodos geoestadísticos. Este yacimiento se localiza al noroeste de la provincia de Pinar del Río, Cuba, las complejidades geológicas de la región indican la inexistencia de homogeneidad en los contenidos de Cu. El análisis estructural muestra alta asimetría de la variable estudiada, la inexistencia de normalidad fue verificada por: diferencias notables entre la media y la mediana, el coeficiente de variación es mayor que 1 y diferencias en la media de los contenidos de Cu en ventanas móviles. Los datos se transformaron logarítmicamente con el objetivo de asegurar la estacionalidad necesaria y consecuentemente lograr la mejor exactitud posible en la estimación de recursos, utilizando la unidad de selección minera (USM) racional. Los datos transformados revelaron un comportamiento más homogéneo, lo cual fue demostrado por mejores resultados en la estadística básica y en valores medios estables en ventanas móviles. Los semivariogramas mostraron estructuras definidas con anisotropía en las direcciones 0° y 90° (considerando 0° al norte). La aplicación del Kriegado Lognormal en la estimación de los recursos es el objetivo principal de este trabajo debido a las complejidades geológicas de la región de estudio.
Análisis próximos y petrografía orgánica del carbón de la formación Los Cuervos en el sector de Chucarima (Chitagá, Norte de Santander) Colombia
Authors: Paredes-Celi Jairo Alonso , Romero-Rincón Luis Miguel , De Bedout-Ordóñez Julián David , Bernal-Ruíz Carlos Mauricio
Published: February 2019

En este estudio se analizaron los macerales y análisis próximos de los carbones de la formación Cuervos perteneciente a la mina La Lomita ubicada en la vereda de San Luís de Chucarima del Municipio de Chitagá (Norte de Santander), la cual está localizada en la cuenca del Catatumbo. Inicialmente, se analizaron las muestras para determinar su poder calorífico, contenido de humedad, cenizas, carbono fijo, azufre y propiedades coquizables. Dando como resultado una muy buena calidad del carbón principalmente por los bajos contenidos de azufre (0.59% en base seca según la normal ASTM D4239-14), con índice de hinchamiento libre de 5.0 secado al aire según la norma ASTM-720M15, lo que le da un fuerte carácter aglomerante haciéndolo un carbón coquizable. Además, a partir del análisis petrográfico, inicialmente se realizó un resumen de las nomenclaturas y características visuales de todos los macerales y después fue posible analizar las muestras obtenidas en el sector. En el cuál, se observó un predominio de la vitrinita haciendo este un carbón vítrico altamente compuesto por kerógeno tipo III presente en cuatro mantos de aproximadamente 30cm de espesor en la zona de estudio.
Investigation of enzyme activity in Hungarian acacia and milkweed honeys
Authors: Szél Zs. , Kardos-Neumann Á. , Biacs P. Á. , Szalai-Mátray E. , Takáts A.
Published: February 2019

Diastase and glucose-oxidase activity was determined in 8 samples of Hungarian milkweed (Asclepias syriaca) honey and in 10 samples of Hungarian acacia (Robinia pseudoacacia) honey. The aim of the study was to compare diastase and glucose-oxidase activity of milkweed and acacia honey. Mean value for diastase was 16.28 diastase number (DN) (±2.53) in acacia honey and 24.48 DN (±5.07) in milkweed honey. Mean value for glucose-oxidase was 3.67 nmol unit g–1 (±3.31) in acacia honey and 8.24 (±4.21) in milkweed honey. The differences both in diastase and glucose-oxidase activities of the two honey types were statistically significant.