bluuebunny/crossref_metadata_2025 huggingface dataset:
Stereotactic radiosurgery with and without checkpoint inhibition for patients with metastatic non–small cell lung cancer to the brain: a matched cohort study
Authors: Shepard Matthew J. , Xu Zhiyuan , Donahue Joseph , Eluvathingal Muttikkal Thomas J. , Cordeiro Diogo , Hansen Leslie , Mohammed Nasser , Gentzler Ryan D. , Larner James , Fadul Camilo E. , Sheehan Jason P.
Published: July 2019

OBJECTIVE

Immune checkpoint inhibitors (ICIs) improve survival in patients with advanced non–small cell lung cancer (NSCLC). Clinical trials examining the efficacy of ICIs in patients with NSCLC excluded patients with untreated brain metastases (BMs). As stereotactic radiosurgery (SRS) is commonly employed for NSCLC-BMs, the authors sought to define the safety and radiological and clinical outcomes for patients with NSCLC-BMs treated with concurrent ICI and SRS.

METHODS

A retrospective matched cohort study was performed on patients who had undergone SRS for one or more NSCLC-derived BMs. Two matched cohorts were identified: one that received ICI before or after SRS within a 3-month period (concurrent ICI) and one that did not (ICI naive). Locoregional tumor control, peritumoral edema, and central nervous system (CNS) adverse events were compared between the two cohorts.

RESULTS

Seventeen patients (45 BMs) and 34 patients (92 BMs) composed the concurrent-ICI and ICI-naive cohorts, respectively. There was no statistically significant difference in overall survival (HR 0.99, 95% CI 0.39–2.52, p = 0.99) or CNS progression-free survival (HR 2.18, 95% CI 0.72–6.62, p = 0.11) between the two groups. Similarly, the 12-month local tumor control rate was 84.9% for tumors in the concurrent-ICI cohort versus 76.3% for tumors in the ICI-naive cohort (p = 0.94). Further analysis did reveal that patients receiving concurrent ICI had increased rates of CNS complete response for BMs treated with SRS (8/16 [50%] vs 5/32 [15.6%], p = 0.012) per the Response Assessment in Neuro-Oncology (RANO) criteria. There was also a shorter median time to BM regression in the concurrent-ICI cohort (2.5 vs 3.1 months, p < 0.0001). There was no increased rate of radiation necrosis or intratumoral hemorrhage in the patients receiving concurrent ICI (5.9% vs 2.9% in ICI-naive cohort, p = 0.99). There was no significant difference in the rate of peritumoral edema progression between the two groups (concurrent ICI: 11.1%, ICI naive: 21.7%, p = 0.162).

CONCLUSIONS

The concurrent use of ICI and SRS to treat NSCLC-BM was well tolerated while providing more rapid BM regression. Concurrent ICI did not increase peritumoral edema or rates of radiation necrosis. Further studies are needed to evaluate whether combined ICI and SRS improves progression-free survival and overall survival for patients with metastatic NSCLC.
Murphey’s teat: history and insight into an enigmatic cerebrovascular eponym
Authors: Heiferman Daniel M. , Li Daphne , Serrone Joseph C. , Reynolds Matthew R. , Germanwala Anand V. , Watridge Clarence B. , Arthur Adam S.
Published: July 2019

Dr. Francis Murphey of the Semmes-Murphey Clinic in Memphis recognized that a focal sacculation on the dome of an aneurysm may be angiographic evidence of a culpable aneurysm in the setting of subarachnoid hemorrhage with multiple intracranial aneurysms present. This has been referred to as a Murphey’s “teat,” “tit,” or “excrescence.” With variability in terminology, misspellings in the literature, and the fact that Dr. Murphey did not formally publish this important work, the authors sought to clarify the meaning and investigate the origins of this enigmatic cerebrovascular eponym.
Ophthalmoplegic complications in transsphenoidal pituitary surgery
Authors: Florea Simona Mihaela , Graillon Thomas , Cuny Thomas , Gras Regis , Brue Thierry , Dufour Henry
Published: July 2019

OBJECTIVE

Ophthalmoplegia is a rare complication of transsphenoidal surgery, only noted in a few studies. The purpose of this study was to analyze the complications of cranial nerve III, IV, or VI palsy after transsphenoidal surgery for pituitary adenoma and understand its physiopathology and outcome.

METHODS

The authors retrospectively analyzed 24 cases of postoperative ophthalmoplegia selected from the 1694 patients operated via a transsphenoidal route in their department.

RESULTS

Two patients were operated on via microscopy and 22 via endoscopy. Patients operated on endoscopically had a greater risk of presenting with an extraocular nerve deficit postoperatively (p = 0.0115). It was found that an extension into or an invasion of the cavernous sinus (Knosp grade 3 or 4 on MRI, 18/24 patients) was correlated with a higher risk of postoperative ophthalmoplegia (p < 0.0001). The deficit was apparent immediately after surgery in 2 patients. For these 2 patients, the mechanisms of ophthalmoplegia were compression or intraoperative nerve lesion. The other 22 patients became symptomatic in the 12–72 hours following the surgery. The mechanisms implied in these cases were intrasellar compressive hematoma (4/22 cases), intracavernous hemorrhagic suffusion, or incomplete resection of the intracavernous portion of the tumor. All patients who did not present with oculomotor palsy immediately after surgery completely recovered their deficits in the 3 months that followed, while the other 2 experienced permanent damage.

CONCLUSIONS

Extraocular nerve dysfunction after transsphenoidal pituitary surgery is a rare complication that occurs more frequently in the case of the invasion or an important extension into the cavernous sinus. In this series, it also appears to be significantly more frequent in patients operated on via an endoscopic approach. Most patients have deficits that appear with a delay of 12–72 hours postoperatively and they are most likely to completely recover.
Manipulacija ponašanjem romantičnog partnera
Authors: Opat Jozić Nikolina , Ombla Jelena
Published: July 2019

Prema gledištu evolucijske psihologije manipulacija uključuje načine na koje ljudi namjerno pokušavaju mijenjati ponašanje drugih (Buss, 1987). Manipulativno ponašanje ima svoj razlog, svrhu ili cilj, a korištenje pojedinih taktika manipulacije ovisi o tome što želimo postići. Vrsta odnosa uvjetuje vrstu taktike koja se smatra primjerenom, a romantični su odnosi osobito bogat izvor informacija o aspektima manipulativnog ponašanja. Cilj je ovoga rada bio utvrditi psihometrijske karakteristike
(konstruktnu valjanost i pouzdanost) prevedenih verzija skala taktika manipulacije (Tactics of Manipulation; Buss, 1992) i emocionalne manipulacije (Emotional Manipulation Scale; Austin, Farrelly, Black i Moore, 2007). Istraživanje je provedeno trima manjim studijama (N1 = 315, N2 = 281, N3 = 168), a sudionici su bili odrasle osobe koje su u romantičnoj vezi. Psihometrijska provjera karakteristika prevedenih i modificiranih verzija Skala taktika manipulacije (Buss, 1992) i Skale emocionalne manipulacije (Austin i sur., 2007) upućuje na to da se u oba
slučaja radi o instrumentima trodimenzionalne latentne strukture i zadovoljavajuće pouzdanosti tipa unutarnje konzistencije. Prema dobivenim rezultatima emocionalna manipulacija pozitivno je, iako nisko,
povezana s korištenjem taktika manipulacije. Drugim riječima, veća sklonost emocionalnoj manipulaciji podrazumjeva i sklonost korištenju taktika manipulacije. S druge strane, emocionalna inteligencija nije značajno povezana ni s emocionalnom manipulacijom ni s taktikama manipulacije.
Penerapan Self Monitoring Program Tingkat Aktifitas Fisik Usia Lanjut di Posyandu Anyelir Bekasi
Authors: Sarasati Budi , Widyasatuti Iin , Saridayani Rafi , Kurniasari Veny , Maarif Sofyan Farid
Published: July 2019

Tujuan Pengabdian Masyarakat ini adalah untuk menerapkan alat monitoring aktifitas fisik untuk para lanjut usia yang tinggal di wilayah Puskesmas Aren Jaya Kecamatan Bekasi Timur kota Bekasi. Praktek monitoring aktifitas lansia menggunakan buku saku berjudul “FIT-Pro”, yang didalamnya terdapat PACE ( Patient-Centered Assessment and Counceling for Exercises ), yang dimodifikasi sesuai dengan aktifitas fisik usia lanjut di Indonesia. Alat ini untuk  mengukur tingkat aktifitas fisik, dukungan sosial dan self-efficacy responden. Partisipan adalah masyakat kelompok umur usia lanjut yang ada di daerah tersebut di atas, berjumlah 35 orang. Pelaksanaan penerapan Self Monitoring Program melibatkan provider kesehatan di wilayah kerja Puskesmas Aren Jaya Kecamatan Bekasi Timur Kota Bekasi. Hasil pelaksanaan menunjukkan bahwa kelompok usia lanjut di wilayah Aren Jaya belum melaksanakan self monitoring aktifitas kesehatan fisiknya secara teratur. Kesimpulan nya adalah Self Monitoring Program dapat diterapkan untuk lanjut usia dalam mempertahan aktifitas fisik sehari-hari, agar tercapai kesehatan yang optimal. Selama pelaksanaan Self Monitoring Program para lansia dan keluarga mencatat  hambatan yang dirasakan, agar pedoman  dapat direvisi dan disempurnakan guna kesejahteraan para usia lanjut.
Einsätze für eine Genealogie des erwachsenenpädagogischen Blicks
Authors: Klingovsky Ulla
Published: July 2019

In diesem Beitrag werden erste Sondierungen für eine Genealogie des erwachsenenpädagogischen Blicks vorgenommen und die These entfaltet, wonach in der Erwachsenenbildung eine systematische Verständigung über die Frage der ,Bildung‘ in der Erwachsenenbildung aussteht. Unter Rückgriff auf den jüngeren bildungstheoretischen Diskurs wird Bildung als Problematisierungsformel vorgestellt, die sich weder bei den funktionalen Entleerungen noch bei den normativen Vereindeutungen von Bildung beruhigt, sondern die Frage nach der Bildung in Erwachsenenbildung offen zu halten sucht.
Offenheit als Stärke von Erwachsenenbildung
Authors: Lerch Sebastian
Published: July 2019

Erwachsenen- und Weiterbildung ist ein heterogenes, vielschichtiges und vielfältiges Handlungsfeld. Das wird u. a. durch unterschiedliche Logiken, Ziele, Aufgaben und Akteur*innen bedingt. Es scheint zugleich lohnenswert, einen „Kern“ zu identifizieren und sich an diesem in Denken und Handeln zu orientieren. Mit „Bildung“ wird dieser Raum erschlossen, markiert und bleibt offen für die Vielfalt erwachsenenpädagogischen Tätigseins.
Disziplinäre Unbestimmtheit – Anregungen für eine veränderte Perspektive auf das Konstitutionsdilemma der Erwachsenenbildung als wissenschaftliche Disziplin
Authors: Seiverth Andreas
Published: July 2019

Im Sinne einer intellektuellen Selbstaufklärung wäre die Emanzipation von der Erziehungswissenschaft der erste und wichtigste Schritt zur Konstituierung der Erwachsenenbildung als eine wissenschaftsautonome gessellschaftliche Reflexionswissenschaft, die eine orientierende Funktion für Praktiken der kulturellen und politischen Erneuerung wahrnehmen könnte. Diese ‚andere Geschichte der Erwachsenenbildung‘ eröffnet eine Perspektive für den Umgang mit ihrer disziplinären Unbestimmtheit.
Lernen als historischer Begriff. Zur historischen Kompetenz nicht nur in der Erwachsenenbildungsforschung
Authors: Manhart Sebastian
Published: July 2019

Der Artikel systematisiert und reflektiert verschiedene Möglichkeiten, wie mit Wertungen und lebenspraktischen Vorannahmen in der historischen Forschung umgegangen werden kann. Da die Vergangenheit immer aus der Perspektive bestimmter Lebensformen und ihrer Problemlagen heraus erforscht und als Geschichte erzählt wird, wird für eine Ethik der normativen Zurückhaltung als zentrales Element einer professionellen historischen Kompetenz plädiert. Die Konsequenzen und Möglichkeiten für die historische Erwachsenenbildungsforschung werden am Beispiel eines normativ reflektierten Umgangs mit dem Lernen aus der Geschichte erläutert.
On the Existence of Kernel Function for Kernel-Trick of k-Means in the Light of Gower Theorem
Authors: Kłopotek Mieczysław A.
Published: July 2019

This paper, constituting an extension to the conference paper [1], corrects the proof of the Theorem 2 from the Gower’s paper [2, page 5]. The correction is needed in order to establish the existence of the kernel function used commonly in the kernel trick e.g. for k-means clustering algorithm, on the grounds of distance matrix. The correction encompasses the missing if-part proof and dropping unnecessary conditions.
A Note on the Durda, Caron, and Buchanan Word Ambiguity Detection Algorithm
Authors: Urban Roman , Anisimowicz Hubert
Published: July 2019

In 2010 Durda, Caron, and Buchanan published a paper in INFOR: Information systems and Operational Research, entitled: An application of operational research to computational linguistics: Word ambiguity. In this article the authors developed “a new measure of word ambiguity (e.g., homonymy and polysemy) for use in psycholinguistic research”. In our work we propose some modification of their algorithm.
Studi Numerik Pengaruh Radial Distance Rectangular Obstacle Pada Tube Banks Fin Heat Exchanger Terhadap Karakteristik Aliran dan Perpindahan Panas
Authors: Romandoni Nanang , Faizin Kholis Nur
Published: July 2019

Tube banks fin heat exchanger merupakan alat yang diaplikasikan untuk mentransfer panas dari liquid-to-air atau refrigerant-to-air. Peningkatan heat transfer dalam alat ini terus dikembangkan yaitu menggunakan obstacle. Penggunaan obstacle selain meningkatkan heat transfer juga berkorelasi dalam peningkatan pressure drop. Oleh karena itu, perlu dilakukan penelitian untuk mengoptimalkan penggunaan obstacle.Analisa numerik secara 2-D dilakukan untuk memperoleh karakteristik aliran dan perpindahan panas pada tube banks fin heat exchanger tersusun staggered yang menggunakan rectangular obstacle. Dalam penelitian ini, kombinasi antara circumferential angle (α) dan radial distance (Rl) dari obstacle dievaluasi secara numerik menggunakan CFD code Fluent. Variasi dilakukan pada α=300 dan Rl/D=0,66-0,90 dengan ReD=4000.Hasil penelitian mengindikasikan bahwa penggunaan rectangular obstacle dengan konfigurasi common flow down pada tube mampu meningkatkan local Nusselt number dan velocity dipermukaan tube. Untuk radial distance, menunjukkan bahwa semakin kecil radial distance, area wake region dibelakang tube semakin berkurang sehingga local Nusselt number dan velocity semakin meningkat. Akan tetapi, penggunaan variasi circumferential angle dan radial distance dari rectangular obstacle secara keseluruhan berkontribusi dalam peningkatan pressure drop. Hasil evaluasi performa menunjukkan bahwa kombinasi yang relevan untuk rectangular obstacle diperoleh pada circumferential angle 300 dan radial distance 0.66.
Fungsi pengarahan kepala ruang dalam pelaksanaan discharge plannning perawat di RS PKU Muhammadiyah Yogyakarta
Authors: Imallah Rosiana Nur , Khusnia Anindita Farda
Published: July 2019

Discharge planning is one indicator of ongoing nursing services that if performed well by the nurses will be able to improve the quality of nursing services and patient satisfaction. One influential factor is the leadership of the head nurse, especially in the function of directing to nurses when carrying out discharge planning. The directional function carried out by the head nurse is in the form of giving motivation, supervision and conflict management. The purpose of this study was to determine the relationship between the function of directional head nurse and the implementation of discharge planning nurses. The study design was descriptive correlational with a cross sectional time approach. The sample in this study were 56 nurses in the inpatient room of PKU Muhammadiyah Yogyakarta Hospital with a sampling technique using simple random sampling. The instrument used was a head nurse directional function questionnaire and discharge planning questionnaire implementation. The data analysis using the Kendall Tau statistical test. The results of this study showed that the assessment of direction function of head nurse were 27 people (48.2%) within adequate category, the implementation of discharge planning were 39 people (69.6%) within good category. The results of the Kendall Tau analysis test were p = 0.002 ( p <0.05). There is a relationship between the function of direction of head nurse to discharge planning nurses.
Telomere Lengthening and Other Functions of Telomerase
Authors: Rubtsova M. P. , Vasilkova D. P. , Malyavko A. N. , Naraikina Yu. V. , Zvereva M. I. , Dontsova O. A.
Published: July 2019

Telomerase is an enzyme that maintains the length of the telomere. The telomere length specifies the number of divisions a cell can undergo before it finally dies (i.e. the proliferative potential of cells). For example, telomerase is activated in embryonic cell lines and the telomere length is maintained at a constant level; therefore, these cells have an unlimited fission potential. Stem cells are characterized by a lower telomerase activity, which enables only partial compensation for the shortening of telomeres. Somatic cells are usually characterized by the absence of telomerase activity. Telomere shortening leads to the attainment of the Hayflick limit, the transition of cells to a state of senescence. The cells subsequently enter a state of crisis, accompanied by massive cell death. The surviving cells become cancer cells, which are capable both of dividing indefinitely and maintaining telomere length (usually with the aid of telomerase). Telomerase is a reverse transcriptase. It consists of two major components: telomerase RNA (TER) and reverse transcriptase (TERT). TER is a non-coding RNA, and it contains the region which serves as a template for telomere synthesis. An increasing number of articles focussing on the alternative functions of telomerase components have recently started appearing. The present review summarizes data on the structure, biogenesis, and functions of telomerase.
Epigenetics of Pluripotent Cells
Authors: Medvedev S. P. , Pokushalov E. A. , Zakian S. M.
Published: July 2019

Pluripotency is maintained by a complex system that includes the genetic and epigenetic levels. Recent studies have shown that the genetic level (transcription factors, signal pathways, and microRNAs) closely interacts with the enzymes and other specific proteins that participate in the formation of the chromatin structure. The interaction between the two systems results in the unique chromatin state observed in pluripotent cells. In this review, the epigenetic features of embryonic stem cells and induced pluripotent stem cells are considered. Special attention is paid to the interplay of the transcription factors OCT4, SOX2, and NANOG with the Polycomb group proteins and other molecules involved in the regulation of the chromatin structure. The participation of the transcription factors of the pluripotency system in the inactivation of the X chromosome is discussed. In addition, the epigenetic events taking place during reprogramming of somatic cells to the pluripotent state and the problem of epigenetic memory are considered.
Effect of 3D Cultivation Conditions on the Differentiation of Endodermal Cells
Authors: Petrakova O. S. , Ashapkin V. V. , Voroteliak E. A. , Bragin E. Yu. , Shtratnikova V. Yu. , Chernioglo E. S. , Sukhanov Y. V. , Terskikh V. V. , Vasiliev A. V.
Published: July 2019

Cellular therapy of endodermal organs is one of the most important issues in modern cellular biology and biotechnology. One of the most promising directions in this field is the study of the transdifferentiation abilities of cells within the same germ layer. A method for an in vitro investigation of the cell differentiation potential (the cell culture in a three-dimensional matrix) is described in this article. Cell cultures of postnatal salivary gland cells and postnatal liver progenitor cells were obtained; their comparative analysis under 2D and 3D cultivation conditions was carried out. Both cell types have high proliferative abilities and can be cultivated for more than 20 passages. Under 2D cultivation conditions, the cells remain in an undifferentiated state. Under 3D conditions, they undergo differentiation, which was confirmed by a lower cell proliferation and by an increase in the differentiation marker expression. Salivary gland cells can undergo hepatic and pancreatic differentiation under 3D cultivation conditions. Liver progenitor cells also acquire a pancreatic differentiation capability under conditions of 3D cultivation. Thus, postnatal salivary gland cells exhibit a considerable differentiation potential within the endodermal germ layer and can be used as a promising source of endodermal cells for the cellular therapy of liver pathologies. Cultivation of cells under 3D conditions is a useful model for the in vitro analysis of the cell differentiation potential.
Gold Nanoparticle Clusters in Quasinematic Layers of Liquid-Crystalline Dispersion Particles of Double-Stranded Nucleic Acids
Authors: Yevdokimov Yu. M. , Salyanov V. I. , Katz E. I. , Skuridin S. G.
Published: July 2019

This work is devoted to the investigation of the methanogenic archaea involved in anaerobic digestion of cattle manure and maize straw on the basis of terminal restriction fragment length polymorphism (TRFLP) analysis of archaeal 16S rRNA genes. The biological diversity and dynamics of methanogenic communities leading to anaerobic degradation of agricultural organic wastes with biogas production were evaluated in laboratory-scale digesters. T-RFLP analysis, along with the establishment of archaeal 16S rRNA gene clone libraries, showed that the methanogenic consortium consisted mainly of members of the genera Methanosarcina and Methanoculleus, with a predominance of Methanosarcina spp. throughout the experiment.
Pulsed Electron Double Resonance in Structural Studies of Spin-Labeled Nucleic Acids
Authors: Fedorova O. S. , Tsvetkov Yu. D.
Published: July 2019

This review deals with the application of the pulsed electron double resonance (PELDOR) method to studies of spin-labeled DNA and RNA with complicated spatial structures, such as tetramers, aptamers, riboswitches, and three- and four-way junctions. The use of this method for studying DNA damage sites is also described.
Design and Implementation a Smart E-Voting Model : Decentralization Using Blockchain
Authors: bindewari Shantanu , Surana Jayesh
Published: July 2019

The transparency of the block-chain allows more auditing and considerate of elections. These attributes are particular of the necessities of a voting system. These features derive from decentralized network, and can bring additional democratic processes to elections, particularly to direct election systems. For e-voting to develop further open, transparent, and independently auditable, a possible resolution would be base it on blockchain technology. In this research work to proposed technique for voting system using blockchain. The blockchain will be publicly provable and distributed in a method that no one will be intelligent to corrupt it. In this research work proposed a blockchain-based model with Consensus Protocol and SHA256 hash algorithm related with the priorities of the ballot-privacy, veri?ability, suitability, extensiveness, uniqueness, sturdiness, and coercion- resistance.
试析土木工程结构设计中的安全性与经济性
Authors: 周 超 , 常 云峰
Published: July 2019

近些年来,在我国城市化进程中,建筑行业获得了迅猛的发展,然而由于技术设计方面存在诸多不足,导致建筑安全事故频发,反而对建筑行业带来了许多负面影响。因此,在土木工程中,经济性和安全性均是影响其发展的重要因素。本文将结合现今土木工程结构设计中存在的常见问题,对提高其经济性和安全性的有效策略进行分析研究。
园林绿化种植的重要性及施工技术分析
Authors: 王 曦
Published: July 2019

园林绿化即选择生长健壮,便于管理的乡土树种,在居住区内,由于建筑环境的土质一般较差,宜选耐瘠薄,生长健壮,病虫害少,管理粗放的乡土树种,这样可以保证树木生长茂盛,并具有地方特色。现今尽管出现了不少的驯化品种,但选择经过长期考验的乡土树种才是植物生长健壮、园林设计管养方便的根本。本文作者结合实际工作经验,对园林绿化种植施工及养护技术进行了分析探讨,提出了自己的看法。
沿线站点物业开发与城市更新的关系
Authors: 刘 睿
Published: July 2019

近年来,随着人类对地下空间资源的日益关注,地铁成为人类利用地下空间的一种有效形式,它对于提高土地利用效率、缓解地面交通、改善人类居住环境、实现人车立体分流、减少环境污染、保持城市历史文化景观等都具有十分显著的作用。
浅谈现代建筑工程施工管理的创新
Authors: 陈 国华
Published: July 2019

现阶段,我国社会经济水平正在不断提升,人们的整体生活质量也有了很大的提升,在这样的时代背景之下,建筑行业的发展迎来了新的契机,人们对于建筑工程行业的要求也在不断提升。21世纪是以科技为主要生产力的时代,为了使建筑工程行业的发展更加稳定,从而获得更大的提升空间,应该对建筑工程管理工作的重要性予以明确,并且要将先进的科学技术手段、管理理论等等应用到房屋建筑管理当中,这样可以使其工程内部管理工作开展的质量得到有效提升。基于此,本文对现代建筑工程施工管理的创新进行了探讨分析。
土木工程施工中边坡支护技术的有效应用
Authors: 罗 毅
Published: July 2019

土木工程的边坡支护工程必须要对土质进行有效勘测,以确保施工环境的安全。同时还需对施工技术加以研究,并制定有效的边坡支护方案,从而确保整个土木工程基础施工的安全性和高效性。本文主要对土木工程施工中边坡支护技术的有效应用进行了探讨。
关于土木工程管理施工过程质量控制策略的思考
Authors: 张 敏捷
Published: July 2019

近年来我国经济的快速发展给整个建筑业带来了巨大的机遇。建筑业同人们的起居生活密切相关,其项目当中的土木工程方面尤为重要。土木工程项目工期长,施工过程比较复杂,很多因素会影响土木工程的施工质量,所以加强对土木工程施工过程质量控制是很有必要的。基于此,本文主要就土木工程管理中建筑施工质量问题进行了分析,并提出了土木工程管理施工过程质量控制措施。
土木工程施工安全管理创新实践研究
Authors: 田 甜
Published: July 2019

伴随我国不断发展文化、经济和政治,人们逐渐提高了对文化、物质的需求。想要人们的需求得到满足,需要加强基础设施建设。土木工程发展飞速,人们越发重视起安全管理问题。施工满足安全要求的同时,还注重设计的风格和美观,如此便使得建设提供工程的难度加大。本文首先阐述了土木工程施工安全管理具备的特征,其次分析了土木工程可持续发展的施工管理模式,以及安全管理中存在的问题,昀后研究了安全管理土木工程施工的创新实践,以供相关人士参考。
基于绿色建筑施工与可持续发展的浅析
Authors: 陈 悦
Published: July 2019

现阶段,我国陆续相关绿色建筑评估标准进行了建设与完善,例如绿色办公建筑评估标准、绿色奥运建筑评估体系、生态住宅评估体系等等,符合我国国情发展的建筑评定体系不断趋于成熟。绿色建筑是环境的反馈和综合思维和建筑工程设计资源效率的应用；随着城市化进程的加快,建筑企业呈现快速发展的趋势。不断加强施工管理,实现绿色施工管理是建筑施工企业发展的必然趋势,到一定阶段。本文从可持续发展的角度详细介绍了绿色建筑的含义和绿色建筑的重要性,并探讨了我国绿色建筑要遵循的原则,昀后就如何创建绿色建筑,提出了相应的解决措施。
装配式建筑施工技术探讨
Authors: 顾 佳宁
Published: July 2019

近几年,国家的建筑工程行业发展十分迅速,不仅创造了较高的经济效益、社会效益,自身的很多功能都在不断的健全,各方面取得的发展成绩是非常值得肯定的。预制装配式建筑属于符合可持续发展理念的新型技术。预制装配式建筑施工技术主要采用模块化的设计,工厂化的生产,车间式的装配和机械化的施工,这一系列先进的生产操作流程,相对而言不仅显著地提高了建筑建设的施工效率,而且让建筑物的建设更加快捷灵活。本文就对预制装配式建筑施工中的一些关键性技术,进行了简要的分析和阐述,希望对我国建筑工程的发展,起到一定程度上的帮助。
建筑给排水工程问题探讨
Authors: 王 永强
Published: July 2019

我国在经济飞速发展的背景下,科技技术有较大的提升,使各领域较快发展,其中建筑工程在此基础上也得到有效的发展,逐步成为了我国支柱型产业,其中给水排水在施工过程中对整个建筑工程的发展起到关键性作用,也是建筑工程中非常关键的组成部分,与人们的日常生活有非常大的关联性。因此在建筑给排水工程施工过程中,还需要进一步的把握好质量,并且做好相关的管控工作。对此,本文主要围绕建筑给水排水工程存在的问题和解决方法做出了探讨。
浅谈建筑工程项目管理
Authors: 黄 康盛
Published: July 2019

建筑工程作为工程领域的一个分支,也是一项关乎民生的工程,随着经济的发展以及不断的吸取国外的先进管理经验,我国的建筑工程管理水平也有了很大的提高,已经形成了一套符合我国实际需要的项目管理体系,同时也拥有了大批建筑工程项目管理人才,但是,我国的项目管理总体水平还是和国外有着很大的差距,需要我们在看到成绩的同时,也要不断的完善我国的项目管理体制,提高我们的项目管理水平。
工民建施工管理要点控制研究
Authors: 艾 忠红
Published: July 2019

工民建施工管理是保障工民建工程施工质量的重要举措。但受到各类主客观因素的干预,导致工民建施工管理环节存在诸多亟待解决的问题,工程施工质量不达标。基于此,本文主要分析了工民建施工管理的作用与问题,并提出了切实可行的改进策略,旨在推动建筑行业的良好发展。
A Correlation Between the Outputs of Education and Training and the Actual Needs of Reality and Aspirations
Authors: Mohammed Al Saadi Mohammed Jassim , Abdul Sayed Abdul Fattah Hassan
Published: July 2019

The human element is the main pillar in the implementation of economic development programs, and therefore the countries have been keen to take care of its rehabilitation within the human resources development progress programs focused mainly on educational curricula.

      Education and training has become an effective and influential tool in the science of development, since the human element is the means and purpose of the movement of progress and development. Countries are comparing and measuring their progress not with their natural resources and wealth in the ground or outside, but measured by their ability to exploit these resources to meet the requirements Its population. As an example, a country like Japan does not possess natural resources such as oil, gas or gold, and it does not have important agricultural resources, but possesses the educated and qualified human element that enabled it to be one of the most advanced countries. Despite its natural wealth, its human wealth and quality have been at the core of its growth and progress. Our country is characterized by a wealth of human resources and, in particular, a high proportion of young people compared to direct countries, It puts pressure on resources to productive energy by developing their productive capacities and competencies and providing them with the skills, expertise and renewable knowledge through continuous training.

      The lack of coordination between the quality of the outputs of education and vocational and technical training and the skilled requirements of the labor market, and the lack of attention and awareness among graduates towards self-employment through the establishment of small enterprises due to the lack of guidance and guidance, the low levels of skills and lack of funding, And to activate and activate the role of the private sector in terms of effective partnership in the effective governance of the system of vocational and technical education and training or in the management of the vocational training system.

      Today, we face a great challenge to adapt ourselves in the face of the urgent and imminent economic changes represented by the fall of customs barriers, borders and the ease of labor mobility. Recent global developments, developments in the economic arena, and the global markets have caused serious disruptions and severe recession, Change the economic outlook and keen attention to local economic conditions and self-reliance to the maximum degree to get out of the cycle of loss between the welfare of the major countries.

     It has been proven from the practical reality that relying solely on education is not enough for the graduates to meet the requirements of the jobs and professions that the labor market needs. This requires training as a means to meet the skills required to practice professions and jobs, especially if it is planned and designed by closely linking to the reality of the market the work
Analysis of the Gap Between the Outputs of Higher Education and the Labor Market in the University (2003-2016)
Authors: Jubouri Sawsan Karim
Published: July 2019

The aim of this research is to study the relationship between the outputs of higher education and the requirements of the labor market in iraq, and to identify the most important factors affecting the level of higher education in it, and the development of some of the necessary treatments to improve the level of higher education, which helps to achieve economic development. The research included two aspects, and the other applied, the research has used quantitative methods to reach that relationship, including the method of measuring the stability of time series of the variables of research, and then measuring the relationship between the outputs of higher education and the needs of the labor market in iraq in the manner of analysis of the joint integration between those variables, as well as a set of research conclusions and recommendations.
The Impact of Strategic Intelligence in the Marketing of University Service
Authors: Brissem Maha Aref , Jamal Dina Hamed , Suleiman Adel Dawood
Published: July 2019

The current research joins between two basic alternatives that have a great importance in the strategic and marketing field which are (the strategic intelligence, marketing university service). The two researchers seek to recognize the scope of influence of strategic intelligence elements in marketing university service of AL-Rafidain AL-Jamia College the research was applied on sample of 34 responders.

     To reach to the aim of research and select of its hypotheses the stoical program (SPSS) was used. The research reached to set of important conclusions which are: There is a relation of influence of the strategic intelligence in marketing university service as well as the research reached to set of recommendations among them. Give great importance to the strategic intelligence as one of the subjects that contributed in success of organizations and inter prices especially the educational ones.
The Impact Of Social Responsibility Drivers On Organizational Excellence Of Government Colleges.
Authors: Rayhan Mohammedi Saad Ali
Published: July 2019

The evaluation of the performance of business organizations is no longer limited to their financial performance or the achievement of their other objectives, but rather extends to the obligations and responsibilities of these organizations towards society in a complex and competitive environment. The Organization's practice of activities of a social nature is a voluntary ethical obligation to society and creates a state of interaction between Organization and its environment. Social responsibility has thus become one of the main objectives of business organizations and is taken into account in formulating the Organization's vision and mission as an objective that the Organization seeks to achieve and no less important than the Organization's goal of achieving profits and maximizing resources. As for the above, the current research dealt with four axes. The first axis dealt with the research methodology, the second axis dealt with the theoretical framework of the research, the third axis dealt with the results of the research, the fourth axis included the main conclusions and recommendations reached by the research
Enhance the Quality of Teaching Services According to the Dimensions of Job Security
Authors: Al Ani Alaa Abdul  Mwojod , Mohammed Abeer Salem
Published: July 2019

The research dealt with the issue of job security and its contribution to the quality of educational services applied to the University of Mosul. The aim of the research was to determine the extent of the sense of job security in Mosul University, as well as the contribution of security factors to the quality of the educational services offered by the University. In order to achieve the objectives of the research, a number of hypotheses were adopted concerning the lack of job security factors that contribute to the quality of educational services.

The research is based on the analytical descriptive approach in the presentation and discussion of the data. The method works by combining the case description with analysis and drawing conclusions. Using a set of statistical methods, the data of the practical side were analyzed, which included an analysis of the responses and opinions of the surveyed individuals at the University of Mosul, which reached (50) individuals. A number of conclusions were reached, the most important of which is the existence of more than one factor of job security that contributes directly to Improving the quality of education in the field
Morfološka karakterizacija sjemenki jagodastih voćnih vrsta
Authors: Skendrović Babojelić Martina , Zečević Alma
Published: July 2019

Veličina i svojstva sjemenki jagodastih voćnih vrsta važan su parametar koji utječe na iskoristivost sjemenki odnosno produkciju pojedinih kemijskih komponenti prilikom njihova iskorištavanja kao nusprodukta prerade plodova. Sjemenke manjih dimenzija potrebno je opisivati s što više parametara, a danas je to moguće računalno razvijenim metodama. Cilj rada bio je utvrditi masu, opisati i analizirati sjemenke jagodastih voćnih vrsta (jagoda, malina, kupina, ribiz, borovnica, ogrozd i josta) pomoću WinSEEDLE™ sustava, a na temelju morfometrijskih svojstava utvrditi razlike između pojedinih vrsta. Nakon provedenih istraživanja može se zaključiti da se jagodaste voćne vrste značajno razlikuju u izgledu kao i morfometrijskim svojstvima sjemenki. Najveća masa stotinu sjemenki utvrđena je kod bijelog ribiza, a najmanja kod šumske jagode i borovnice. Najveća projicirana površina te ravna duljina
i ravna širina sjemenki utvrđena je kod bijelog ribiza, nešto manje vrijednosti utvrđene su kod kupine, a najmanje kod jagode. Analiza sjemenki pomoću novijih sofisticiranih metoda predstavlja značajan izvor
podataka za dopunu istraživanja u vrednovanju vrsta i sorata. S obzirom
da pojedine jagodaste voćne vrste sadrže dosta velik broj sjemenki koje
uglavnom ostaju neiskorištene ili najčešće predstavljaju nusproizvod čak i otpad prilikom prerade plodova, rezultati ovakvih istraživanja mogu olakšati odabir pojedine vrste za određenu namjenu.
Study The Severe Effects of Iron Compounds Presenting in Sandstone on the Deterioration of Wall Paintings of Archaeological Tombs in Bahariya Oasis - Egypt
Authors: Kader RabeaRadi Abdel , El –Sayed ShaimaaSayed Mohamed , Abo-El Yamin Ahmed
Published: July 2019

The Wall paintings in Bahariya oasis expose to various deterioration factors, especially the resulted deterioration from the geological nature of sandstones' supports; sandstone of Bahariya formation is considered the weakest sandstone type in Egypt because of its geological formation which contains a very big percentage of iron oxides. Sandstone samples were taken, analyzed and examined by x-ray diffraction and scanning electron microscope, the iron oxides are thecement material in sandstone which affect negatively on the wall paintings in the selected tombs (Badi –Ishtarand Bannantiu tombs),they caused a lot of deterioration phenomena to the wall painting layers like: layers loss,black spots, cracking through all the layers and sandstone support weakness that threatens the remaining wall paintings and the safety of the tombs. Iron oxides percentage in Badi – Ishtartomb is more than Bannantiu tomb and this is reflected on the wall paintings case in Badi – Eshtar. This research sheds the light on this phenomenon and its effect on the wall painting's deterioration.
On the Performance of Transmuted Logistic Distribution: Statistical Properties and Application
Authors: Samuel Adeyinka Femi
Published: July 2019

In this article we transmute the logistic distribution using quadratic rank transmutation map to develop a transmuted logistic distribution. The quadratic rank transmutation map enables the introduction of extra parameter into its parent model to enhance more flexibility in the analysis of data in various disciplines such as biological sciences, actuarial science, finance and insurance. The mathematical properties such as moment generating function, quantile, median and characteristic function of this distribution are discussed. The probability density functions of the minimum and maximum order statistics of the transmuted logistic distribution are established and the relationships between the probability density functions of the minimum and maximum order statistics of the parent model and the probability density function of the transmuted logistic distribution are considered. The parameter estimation is done by the method of maximum likelihood estimation. The flexibility of the model in statistical data analysis and its applicability is demonstrated by using it to fit relevant data. The study is concluded by demonstrating that the transmuted logistic distribution performs better than its parent model.
Phytoremediation of Heavy Metals Released from Mining Waste Drainage using selected plant species, in Ethiopia
Authors: Gebru Mehari Girmay
Published: July 2019

Mining is known in releasing of heavy metals and environmental pollutants due to their toxicity, persistence in the environment, and bio-accumulative nature. Leaching activity of mining has a major role in releasing of chemicals which toxify to the mining environment. Such activity contaminates the terrestrial ecosystems with toxic heavy metals that lead to the environmental problem of public health concern. In Ethiopia, even the mining trend is accounted long time, the environmental and social impacts are underestimated and not taken as an issue for a long time. However, these impacts are become very risky and problematic from time to time, since mining companies are not dedicated to their environmental and social impact assessment commitments. Being persistent pollutants, heavy metals accumulate in the environment and consequently contaminate the food chains. Accumulation of potentially toxic heavy metals in biota causes a potential health threat to their consumers including humans. Phytoremediation is more cost-effective than alternative mechanical or chemical methods of removing hazardous compounds from the soil. Vetiver grass is a perennial grass belonging to the Poaceae family with short rhizomes and a massive, finely structured root system. The deep root system makes the vetiver grass extremely drought tolerant and very difficult to dislodge when exposed to strong water flow. The main purpose of this study is to review the ecological impacts of mining in releasing leached wastes/drainages/ and the possible and effective techniques of treatment via Phytoremediation technology.
Development of Brochure-Based Teaching Materials on Persuasive Text in Grade 7th Students of Junior High School Dwi Tunggal Tanjung Morawa
Authors: Haryati Sri , Lubis Malan , Ansari Khairil
Published: July 2019

This study aims to find out the developmentof brochure-based teaching materials on persuasive text in grade 7th students.The object of this study is grade 7th students of Dwi Tunggal Tanjung Morawa. The result shows that The process of developing the development of brochure-based teaching materials on persuasive text material was carried out in three stages, namely the preliminary study phase, the initial product development and product testing. At the stage of the preliminary study an analysis of the needs of teachers and students was carried out. The results of the needs analysis obtained data that 100% of teachers and students of Junior High School Dwi Tunggal Tanjung Morawa need teaching materials in the Indonesian language learning companion. In the initial product development stage, product design and product validation were carried out to 2 material experts and 2 media design experts. After the validation process, the product is declared feasible for testing. In the third stage, product testing was carried out in three ways, namely individual trials, small group trials and limited field trials. Individual trials obtained an average percentage of 88.19% with the category "Very good", the small group trial received an average percentage of 89.58% with the category "Very Good". Limited field trials received an average percentage of 91.01% with the category "Very Good". Based on these data, obtained appropriate teaching materials to be used by teachers and students in learning.
Rendimiento del ultrasonido en el diagnóstico de acretismo placentario en el Instituto Nacional Materno Perinatal
Authors: Huertas-Tacchino Erasmo
Published: July 2019

Objetivos. Determinar la sensibilidad y especificidad del ultrasonido en la detección prenatal del acretismo placentario. Materiales y Métodos. Diseño: Estudio observacional analítico retrospectivo Lugar: Unidad de Medicina Fetal. Instituto Nacional Materno Perinatal. Lima-Perú. Participantes: Gestantes que acudieron a la Unidad entre el 02 de enero y el 31 de diciembre del 2012, para realización de ecografía obstétrica por sospecha de acretismo. Se revisaron las historias clínicas de 93 pacientes evaluadas mediante ecografía durante el segundo y tercer trimestre buscando signos de acretismo, comparando luego con los hallazgos durante el parto y la anatomía patológica. Resultados. La sensibilidad del diagnóstico ecográfico de acretismo placentario es de 90.9% y la especificidad de 99%. La edad gestacional al momento del diagnóstico ecográfico fue en el 50% de casos entre las 32 y 36 semanas, siendo el diagnóstico más precoz el realizado a las 25 semanas. En el 100% de los casos el diagnóstico ecográfico de acretismo estuvo asociado al hallazgo de placenta previa y en el 70% de culminó en cesárea + histerectomía Conclusiones: El ultrasonido es una herramienta útil en el diagnóstico prenatal de acretismo placentario. Debe sospecharse en toda paciente con diagnóstico ecográfico de placenta previa.
Factores de riesgo de preeclampsia, una actualización desde la medicina basada en evidencias
Authors: Guevara-Ríos Enrique , Gonzales-Medina Carlos
Published: July 2019

La preeclampsia constituye un problema de salud pública en medicina materno perinatal y el reconocimiento de los factores de riesgo es de vital importancia para su manejo inicial. Asimismo, el vertiginoso avance de la ciencia y la investigación, nos compromete a revisar desde el enfoque actual de la medicina basada en evidencias (MBE) los nuevos hallazgos que sustentan el reconocimiento de los potenciales factores riesgo de nuestras pacientes en la práctica clínica diaria. Por ello el objetivo de la presente revisión es documentar desde el enfoque de la MBE las últimas publicaciones en relación al estudio de los factores de riesgo de preeclampsia.
Embarazo ectópico intersticial: diagnóstico clínico y tratamiento
Authors: Benel-Chamaya Aldo , Arango-Ochante Pedro M. , Loayza-Breña Juan , Siguenza-Vasquez Kyra , Remy-Paredes Nicola
Published: July 2019

El embarazo ectópico intersticial es un tipo raro de embarazo tubarico que plantea un desafío diagnóstico y de tratamiento. Se asocia con un mayor riesgo de sangrado masivo e incontrolable. Este es un caso raro de embarazo ectópico intersticial diagnosticado en el primer trimestre del embarazo por ecografía y tratado quirúrgicamente con incisión longitudinal del miometrio y posterior resección cornual.
Revista de investigación rumbo a la modernización digital
Authors: Ayala-Peralta Félix Dasio
Published: July 2019

La Revista Peruana de Investigación Materno Perinatal órgano oficial de difusión científica del Instituto Nacional Materno Perinatal (INMP) ha logrado ingresar a la modernización mediante el uso de la plataforma electrónica Open Journal System (OJS), la cual brindará una mayor visibilidad a la producción científica realizada en el INMP.

Al estar en el sistema del Open Journal System (OJS) la revista cuenta con un código internacional seriado en línea ISSN-L 2663-113X, quiere decir que la revista en su versión electrónica está visible a toda la comunidad científica, tanto nacional como internacional, cumpliendo de este modo con las normas establecidas para publicaciones científicas.

El INMP viene publicando desde hace 8 años la Revista Peruana de Investigación Materno Perinatal en versión impresa con ISSN 2305-3887, la cual hasta la fecha han producido en su totalidad 121 artículos que ya se encuentran en línea y cada uno cuenta con Digital Object Identifier (DOI) que es un identificador único y permanente para las publicaciones en la red la cual garantiza el crédito académico de los investigadores que publican en nuestra revista.

En la actualidad, los artículos científicos producidos y publicados en vuestra revista del INMP tendrán mayor visibilidad porque cualquier investigador va a poder encontrarlos en la red, estos podrán citarlos como referencia en otros trabajos de investigación, dando inicio a la modernización en nuestras publicaciones como instituto de salud de nivel III-2 en el país.

A partir deL 2019, la edición de producción científica de vuestra revista en el INMP será más exigente y se realizará de manera trimestral, los artículos científicos serán inicialmente evaluados por revisores pares externos para luego ser aprobados por el Comité Editorial de la Revista, asegurando de este modo que los artículos sean de calidad y cuenten con los parámetros que las normas internacionales exigen.

Cabe mencionar que el INMP es el único instituto que ha logrado que una revista de investigación se encuentre indizada en LATINDEX  y migrado al Open Journal System, el próximo paso es indizar la revista a plataformas como Scielo y otras. “Este es un proyecto sostenible, el camino está trazado para que la revista llegue a ser indizada a Scopus que es una base de datos bibliográficas del más alto nivel”. Vuestra revista está disponible en el link: http://investigacionmaternoperinatal.inmp.gob.pe/index.php/rpinmp