bluuebunny/crossref_metadata_2025 huggingface dataset:
Method for the quantative determination of β-hydroxysimvastatin in blood plasma
Authors: Popova N M
Published: October 2016

Article is devoted working out of an original HPLC method of quantitative determination of β-hydroxysimvastatin in the blood plasma. In work the HPLC system "Stayer" with the spektro-photometric detector was used. Analysis was achieved on the reversed phase column «Beckman Coulter». Separation of β-hydroxysimvastatin from the blood plasma carried out a method liquid Extraction
Modern views on the relationship of the upper and lower respiratory tract in allergic rhinitis and asthma
Authors: Gusсhin M Y , Barkhina T G , Golovanova V E , Polner S A
Published: October 2016

Research presented in a modern perspective on the problem of cellular-humoral and immunological interactions of the upper and lower airways in allergic rhinitis and bronchial asthma. The mechanisms of hyper-nasal mucous membranes and bronchial tubes in the tissue, cellular and subcellular levels. The correlation between damage to the epithelial and stromal cells and early debut of the disease and the severity of the pathological process.
Peculiarities of regression of limb ischemia after ligation operation in drug-addicted patients with post-injection pseudoaneurysms of peripheral arteries in the long-term period
Authors: Karpov V V , Shvalb A P , Gryaznov S V
Published: October 2016

We performed a comprehensive analysis of the state of limb circulation after the extended ligation of main arteries of iliofemoral segment in drug-addicted patients with post-injection pseudoaneurysms in the long-term period (1-3 years). We used both clinical and instrumental methods. We observed that 92% of patients with limb salvage in the short-term period show stable regression of ischemia in the long-term period.
Gene pharmacotherapy Inoperable patients with chronic lower limb ischemia
Authors: Shvalb P G , Kalinin R E , Deev R V , Gryaznov S V , Mzhavanadze N D , Kiselev S L , Isaev A A
Published: October 2016

The article presents the results of the comparative six-month surveillance inoperable patients with atherosclerosis of lower extremities with clinical manifestations in the form of intermittent claudication (IIa-III century. AVPokrovskii to Fontaine), which are composed of conservative therapy received the drug genterapevtichesky "Neovaskulgen", a plasmid with the gene structure of vascular endothelial growth factor. The study included 50 patients (35 – in the clinical group and 15 – in the control group). The drug was administered intramuscularly, as close as possible to areas of ischemia, twice, at doses of 1.2 mg, with an interval of 14 days. Patients kontralirovlai: the length of pain-free walking distance, ankle-brachial index, transcutaneous oxygen napryazhdenie determined, the linear velocity of blood flow in the affected segment. It is established that in the clinical group were significantly increasing the length of pain-free walking distance, the linear velocity krovtoka. To a lesser extent the other indicators are growing. In the control group had deterioration of patients. The obtained results show the effectiveness of the drug "Neovaskulgen."
Pharmacokinetic of simvastatin at experimental hypothyreosis
Authors: Yakusheva E N , Popova N M
Published: October 2016

In article data of the research devoted to studying of pharmacokinetic of simvastatin at experimental hypothyreosis are resulted. It is shown changes of pharmacokinetic parameters of main metabolite of drug – β-hydroxyacid of simvastatin, which says about decrease of bioavailability and correlation of these changes with level of T4.
Estimation doctors of material base of the departmental hospital
Authors: Laktionova L V
Published: October 2016

The article presents the results of sociological survey of doctors in one of the FMBA hospitals of Russia concerning an estimation of its material and technical base (MTB) are resulted. Features of estimations MTB are revealed by doctors-heads and doctors-experts.
The comparative hygienic analysis of the vehicle density in Ryazan districts
Authors: Lyapkalo А А , Dementiev А А , Tsurgan А М
Published: October 2016

The articles includes the results of observation of the vehicle density and a comparative analysis of the transport conditions on weekdays and at weekends in warm and cold seasons in Ryazan districts. The maximum traffic load was observed in the city centre and the minimum one was in Moscowsky district of Ryazan.
The health of children-orphans and children, In difficult life situations (based on materials Ryazan region)
Authors: Petrovа E I
Published: October 2016

The paper presents an analysis of health status residing in institutions for orphans and children in difficult situations on the basis of clinical examination, which aims tomonitor the health status of effectiveness of therapeutic and corrective measures.
The complex analysis of a personnel maintenance of children's out-patient-polyclinic establishments of Ryazan
Authors: Chvireva N V
Published: October 2016

In article the results of the analysis of a personnel potential on an example of children's out-patient-polyclinic establishments of Ryazan are resulted. The author had been studied the basic problems complicating activity of establishments of a primary link, and precisely – the provision by paediatricians, experts in the conditions of deficiency of financing under the given item of expenses, the dynamics of the quotient of pluralism, the level of a professional trainings of a medical personnel.
Predictors of poor prognosis in chronic heart failure
Authors: Smirnova E A
Published: October 2016

he estimation of prognosis and identification of mortality predictors in CHF patients are one of the important clinical goals. 4-year survival rate in 167 patients with verified CHF NYHA I-IV, revealed by screening of representative sample in Ryazan region, is 76,6%. The main factors impairing prognosis in population are age and functional class of CHF.
RECURRENCE OF BREAST CANCER AFTER CONSERVATIVE TREATMENT
Authors: El Aifi Hichem , Kukikov E P , Shomova M V
Published: October 2016

Based on clinical data were obtained by the results of treatment of breast cancer after conservative surgery and the relation between diagnostic factors and relapse of the disease, depending on its location and morphological forms.
Dynamics of Indicators electrical conductivity of dental hard tissues IN THE TREATMENT OF hypersensitivity with a complex preparation containing potassium fluoride and ecdysterone
Authors: Ogneva A N , Darmogray V N , Morozova S I , Tabolina E S
Published: October 2016

Done examination and treatment of 87 patients aged from 21 to 58 years with hypersensitivity hard tissue caused by the non-carious lesions (wedge-shaped defect, abnormal abrasion, erosion) and gingival recession. Treatment of hyperesthesia of hard dental tissue was performed using a complex preparation containing potassium fluoride and ecdysterone. The effectiveness of the treatment was evaluated by the dynamics of changes of parameters of electrical conductivity of dental hard tissues before treatment, immediately after the course of treatment and at 1, 6 and 12 months. The study revealed decrease in electrical conductivity in all groups studied, indicating the high performance of treatment of sensitivity dental hard tissues by complex preparation containing potassium fluoride and ecdysterone.
The mass-spectrometry study of different blueberry (Vaccinium uliginosum) organs element composition
Authors: Talanov A A , Kruglov D S , Fursa N S
Published: October 2016

The element composition of overground and underground Vaccinium uliginosum organs was determined by mass-spectrometry method.
MORPHOLOGICAL CHARACTERISTICS OF HUMAN TRACHEA AND BNOCHI GLANDS OF SMOKING AND NON-SMOKING ADULT MEN
Authors: Kolesnicova E V , Sidorova E I , Mihailova L P , Makarova O V
Published: October 2016

This work describes macroscopic, hystological and morphometrical study of human trachea and bronchi glands of smoking and non-smoking adult men. The study shows that number of excretory ducts of the glands in trachea, main right and distal bronchus is 3-4 times larger for smokers, rather that for non-smokers. Also, a growth of volumetric fraction of bronchial glands and mucous acini in main right and common bronchi was reliably identified for smokers versus non-smokers. These findings indicate that smoking not only increases the volumetric fraction of glads in bronchial wall, but also leads to growth of number of glands.
Involutive changes of pelvicalyceal system of person’s kidneys according to ultrasound and morphologic studies
Authors: Stabredov A V , Kafarov E S
Published: October 2016

The purpose of this study is to study age-dependent changes of calix and pelvis. Morphometric sizing of 68 people from the age of 30 to 89 was carried out. 100 corrosion preparations of pelvicalyceal system of kidneys were made. Histilogic sections of calix and pelvis of 32 kdneys were painted by hematoxylin-eosin, by Van-Gizon and Mallory. The data of ultrasound diagnostic of kidneys of 66 people (132 kidneys) from the age of 13 to 80 without pathobiology were studied. Against the background of involution of the sizes of kidneys, the volume of pelvicalyceal system increases. In spite of the fact that the average indicants of the volume of pelvicalyceal system in this period fall down, in some cases pelvis can be widen. It is found out that in geratic age the paries of pelvis become thinner. It can be connected both with the changes of the structure of the paries itself and with the widening of the pelvis due to obstructive nephropathy with the people of this age ( it is more common with males).
Dynamics of some biochemical parameters in patients with peripheral occlusive arterial disease at different periods following reconstructive surgery
Authors: Kalinin R E , Suchkov I A , Nikiforov A A , Phennikov A S
Published: October 2016

According to various authors and our own experience, intimal hyperplasia develops in 40-50% cases following reconstructive surgeries causing complications in post-operative period by the development of restenosis. Nowadays more importance in the development of intimal hyperplasia is given to the dynamics of different biochemical parameters of blood plasma. This work represents the analysis of blood plasma endothelin-1, adhesion molecules and C-reactive protein rates in patients with peripheral occlusive arterial disease at different periods following reconstructive surgery. Research was performed in 25 male patients with peripheral occlusive arterial disease stage IIb-IV according to Fontaine-Pokrovsky classification who underwent reconstructive surgery with the use of allo-prostesis.
THE STUDY OF THE DIRECT ANTIOXIDANT ACTIVITY OF PHYTOECDYSTERONE IN VITRO
Authors: Shchulkin A V , Yakusheva E N , Davydov V V , Darmogray V N
Published: October 2016

In vitro studies revealed that phytoecdysterone isolated from Silence nutans and Silence tatarica activates the formation of superoxide in model systems of quercetin and adrenaline autooxidation. It is shown that phytoecdysterone suppresses the development an ascorbate and NADPH 2-dependent iron induced lipid peroxidation. Phytoecdysterone is comparable with cudesane (vitamin E and coenzyme Q10) on ability to suppress ascorbate-depend lipid peroxidation.
AGE ASPECTS OF VEGETATIVE REGULATION CARDIO-VASCULAR SYSTEM BY SPORTSMEN OF BOTH SEXES
Authors: Kudrya O N
Published: October 2016

In this article are described the peculiarities of vegetative regulation cardio-vascular system by sportsmen of both sexes. It is established that maturation of segment sections of vegetative nervous system by sportsmen of both sexes is proceeded heterochrony. Functional activity of the highest oversegment structurs of vegetative nervous system which participate in forming adaptive answer cardiovascular system in response to orthostatic influence is shown at the age of 9 – 14 years and don't depend on sex of person.
TEENAGERS’ SMOKING AS MEDICO-SOCIAL PROBLEM
Authors: Dmitrieva O V , Kazaeva O V
Published: October 2016

In this article there are the results of the studies on smoking among teenagers in the age 14-17 years. 254 school children of 9-11 classes were examined. The conclusion about the high level of smoking prevalence among children and teenagers has drawn. This fact considerably determines unfavorable prognosis of the population health state in the near future. Solution of this most important medico-social problem requires urgent measures on preservation and promotion of health of the younger generation, what provides the different levels and courses of actions.
TENDENCIES OF MORTALITY OF THE RUSSIAN TEENAGERS FROM SUICIDES IN COMPARISON WITH OTHER EXTERNAL CAUSES OF DEATH
Authors: Chernobavsky M V
Published: October 2016

The article presents results from analysis of the dynamics of russian teenagers mortality 15-19 years from suicides in different periods of social and economical development of the country. The estimation of the evolution of teenage mortality from suicide on the background from death and traumas as a whole is given.
LOAD-CARRYING CARDIOLOGY: WORKING RESULTS AND THEIR DISCUSSION
Authors: Agafonova L V , Zaikina N V
Published: October 2016

The test with the physical activity is the most frequent cardiologic test, used for diagnostics of the coronary heart disease (CHD), for prediction of the disease and valuation of the therapy effectiveness. Load-carrying test was prosecuted using tredmil, protocols were standard and universal (BRUCE, МOD BRUCE, J.Naughton). The selection of the protocol type was individual. There were examined 294 patients, among that men of 40-60 years prevailed. Were also analyzed: frequency of using of the indicated protocols (87,8% – МOD BRUCE); results of the test (8,8% – positive tests, 73,2% – negative tests, 7,1% – doubtful tests) and executed loading in metabolic units.
THE INFLUENCE OF HYPERVENTILATION ON LIFE QUALITY OF PATIENTS WITH BRONCHIAL ASTHMA
Authors: Rakita D R , Kuspanaliyeva D S
Published: October 2016

Nowadays the problem of life quality estimation is of great concern. The aim of our investigation was to show how presence of hyperventilation syndrome influences the life quality and asthma control of patients. 78 patients were examined. It was shown that hyperventilation has a negative influence on life quality and asthma control of the patients.
THE COMPARATIVE EFFICIENCY OF CHONROITINE SULFATE AND HYALURONIC ACID IN PATIENTS WITH OSTEOARTHRITIS OF THE KNEE JOINT
Authors: Dolgova E A , Zaigrova N K , Rakita D R
Published: October 2016

Comparative evaluation of the effectiveness of treatment of patients with osteoarthritis of the knee joint (OA COP) with chondroitine sulfate (CS) and intra-articular injection of hyaluronic acid (HA), as well as their impact on the demand in NSAID therapy and life quality of patients.45 patients (males and females) with OA of the COP in age from 35 to 82 years with duration of disease 7 years were included into the 12-month study. We used SF-36, VAS, radiography and MRI. Patients were devided into 3 groups: Group 1 – intra-articular injections of glucocorticoids 1,0 ml 3-5 a week, Group 2 – 500 mg CS, 1 capsule 2 times a day for 6 months. Group 3 – taking only NSAIDs.There was a significant symptomatic effect of corticosteroids and CS. Therapy with corticosteroids and CS showed slower progression of OA of the COP, that allows to refer them to structural-modifying drugs.
CALL FOR INTERACTION OF ULTRASOUND IN RATS
Authors: Pertsov S S , Koplik E V , Saharov D S , Sudakov K V , Karkischenko N N
Published: October 2016

The article presents data illustrating the changes in the characteristics of ultrasonic vocalizations in rats (mean frequency, duration and power ranges of ultrasonic waves) in acute emotional stressor impact. In the ultrasonic vocalizations of rats reflects individual motivation emotive, dominating at a certain time. These data illustrate the importance of ultrasound information in mammals.
Expression of GABA transporter (GAT-1) and GLIAL FIDRILLAR ACIDIC PROTEIN (GFAP) in maturated human neocortex
Authors: Godovalova O S , Savel’ev S V
Published: October 2016

GABA transporter (GAT-1) distribution in the human neocortex sulcuses (fetus from 14 weeks prenatal till four years old human) was researched by immunohistochemistry method. Intensive GAT-1 positive staining in the fissure lip from fetus neocortex was detected. GAT-1 positive staining decreased with different intensivity in the sulcuses and in the straight surfaces of neocortex, depended of fetus age. After birth the lips and the straight surfaces of neocortex was stained uniform, but was kept the decay of labeling in the fissures. From 26 till 33 prenatal weeks GAT-1 positive terminals innervated subventricular/ventricular zone, where they blocked cell progenitor proliferation, whereby triggered the astrocytic differentiation.
Academician I.P. Pavlov – a prophet of scientific, social, and political ideas in Russia in the XXI century
Authors: Bolondinsky V R , Samoilov V O
Published: October 2016

Pavlov’s ideas, scientific principles and, on the whole, his world outlook in the field of physiology, neurology, education, and psychology are in the foundation of these concepts in the XXI century. His democratism, free-thinking, protests against repressions and terror are what has become reality in the XXI century in Russia. Being an atheist, he came out against persecution of religion, for freedom of personality and independent existence in the country of different parties and organizations, including the Academy of Sciences.
THERMAL CONDITION OF THE ORGANISM OF THE WORKERS employed PROCESSED battery scrap
Authors: Chudinin N V , Kiryushin V A , Bolchakov A M
Published: October 2016

The choice of method for processing of secondary lead in many respects determines the sanitary conditions of labor. Complex comparative approach to the study of existing conditions reveals the most negative factors affecting the workers and to quantify the existing differences. We conducted a prospective study in non-ferrous metals industry, has revealed that one of the disadvantages of the working environment is heating microclimate. Statistical analysis allowed us to establish priorities for the factors acting on the heat-stressed body workers, and to quantify the differences in thermal effects and thermal state of the organism of workers employed by different methods of recycling of lead.
NEED OF PATIENTS WITH CONCOMITANT INJURIES IN MEDICAL SPECIALISTS’ CONSULTATION AND CLINICODIAGNOSTIC TESTS
Authors: Zhelezin O V , Konovalov O E
Published: October 2016

In the article the questions of needs of patients with concomitant injuries in consultative and clinicodiagnostic care in hospital environment have been given consideration to. The main trends in improvement of therapeutic–diagnostic tactics at pre-hospital and hospital levels of medical care delivery in case of concomitant injuries have been presented.
PSYCHOLOGICAL AIMS IN THE CLINICAL WORK OF THE CANCER CARE PROFESSIONALS
Authors: Malova Y V
Published: October 2016

Revue describes the modern approaches in understanding of the psychological goals in clinical cancer care. The components of the professional activity such as building of confidence and emotional responsibility, individual psychological attitude, understanding of basic psychological needs, are considered. The influence of the psychological well-being on quality, such as on duration of cancer survival, is stressed. The psychological aims and principles of communication in children cancer care and family consulting are described. The importance of the psychological need “to be known” is stressed as one of the most meaningful for the development of the effectiveness of clinical cancer care.
Psychological defense mechanisms of patients with epilepsy AND FACTORS DETERMINING THEIR
Authors: Krivtsova A Yu , Zhadnov V A , Yakovleva N V
Published: October 2016

Expression of individual defense mechanisms in patients and healthy people varies. Leading psychological defense mechanism of patients with epilepsy – regression, and the vast majority of these patients have a disability group. Several defense mechanisms are associated with specific clinical and psycho-parameters, which leads to the predominance of a particular type of personal protective behaviors.
VARIABILITY OF PARAMETERS OF NEPHRITIC VEINS IN THE COURSE OF AGING
Authors: Kafarov E F , Stabredov A V
Published: October 2016

146 preparations of kidneys of people, at the age from 21 years till 85 years which were lost from diseases, not connected with a pathology urological system are investigated. Methods of anatomic preparation are used and 146 corrosion preparations of venous system of a kidney of the person are made. Also the data 76 МСКТ and 34 МРТ has been used. The morphometry data was processed by methods of variation statistics on the personal computer under programs «Excel» (Ver.10.2701) and «Statwin» (Ver.5.1). The research analysis has shown that with the years there is a gradual increase in diameters of nephritic veins (till 50 years), however this process proceeds non-uniformly. Parts of a nephritic vein differ the form, in the sizes, a wall structure, individually changeable, and have topometrytical features. External diameter, thickness of a wall, internal diameter and the area of cross-section section of a gleam, the relation of a thickness of a wall to diameter of a gleam of parts of a nephritic vein, change in the course of aging non-uniformly.
Comparative characteristic of the quality of life of mental patients of various nosological group having in-patient treatment
Authors: Petrov D S
Published: October 2016

In the article the question of life quality of mental patients has been studied. We present the results of investigations of life quality of a group of schizophrenic patients, patients suffering from schizotypical disorders with various duration of disease to Ryazan regional clinical psychiatric inpatient hospital. The results have been obtained with the help of WHOLQ-100 questionnaire. We’ve estimated showings of fundamental spheres and subspheres of the respondents’ life. The importance of life quality showings of mental patients of various nosological categories taking in to account the duration of disease in case of optimization of therapeutic- rehabilitation actions has been given attention to.
ADOLESCENT PREGNANCY AND BIRTH – OPTIMIZATION OF OBSTETRIC MANAGEMENT
Authors: Petrova Y A
Published: October 2016

This article presents the problem of pregnancy of minors. As a result of the undertaken study it was established that pregnancy and birth complications as well as newborn distress for minor mothers are typically higher than for women of optimal reproductive age. Recommendations concerning optimization of obstetric care for young women are presented.
FACTOR OF IMMUNOLOGICAL CONTROL IN THE TACTICS OF MANAGING OF PATIENTS WITH URGENT SURGICAL PATHOLOGY
Authors: Fedoseev A V , Abuvarda F H , Budarev V N , Muraviev S U , Mikhaylov I A
Published: October 2016

For successful treatment of patients with urgent surgical pathology the deep knowledge of different clinical syndromes is necessary. One of such syndromes is the syndrome of enteric insufficiency. As the result of our research the presence of statisticaly reliable connection between the immunological indexes and the expression of this syndrome was found.
The dynamics of adrenal cortex and renal renin-angiotensin system hormone level of the patients with simple solitary cysts, complicated by symptomatic arterial hypertension
Authors: Cherenkov A A , Aristarkhov V G
Published: October 2016

The article deals with the results of the symptomatic arterial hypertension surgical correction of 95 patients, suffering simple solitary renal parenchyma cysts. These patients were examined for hormone levels of renin, aldosterone and cortisol versus figure dynamics of systolic and diastolic arterial tension. A hypothesis about a dependence of arterial hypertension forming mechanism on simple renal cyst topography is formulated on the basis of data analysed.
Pathologic teeth and oral cavity mucous membrane of cellulose-paperfactory workers
Authors: Amirhahov T N , Dergunov A V
Published: October 2016

This research reveals in finance of professional pathogenic factors of cellulose-paper industry on oral cavity membrane and teeth tissues of cellulose-paper factory workers. Due to this connection methods of prevention and cure of workers cavity illnesses are founded on the pathogenesis
Embolism of main arteries in atrial fibillation
Authors: Kalinin R E , Suchkov I A , Boguto O N
Published: October 2016

The abstract represents the analysis of incidence of embolism of main arteries in atrial fibrillation, peculiarities of clinical picture, different classifications of acute ischemia, matters of techniques of treatment and prophylaxis of embolism, and treatment strategy for embolism of main arteries based on data published in foreign and national literature.
EVALUATION OF ADAPTATION BY MEANS OF VARIABILITY OF CARDIAC RHYTHM ANALYSIS IN SURGICAL AND ONCOLOGICAL PRACTICE
Authors: Semionkin E I , Kulikov E P , Trouchin S N , Bublikov I D
Published: October 2016

In the investigation literature analysis data are given, which concern a possibility of cardiac rhythm analysis use in surgery and oncology to evaluate adaptation processes.
NEUROVISCERAL COUPLING DURING EMOTIONAL RESPONDING IN MAN
Authors: Aftanas L I , Brack I V , Makhnev V P
Published: October 2016

Assessment of defensive behavior in the cardiovascular system is based on the presentation of an intense aversive unexpected stimulus that prompts a specific phasic cardiovascular reactivity pattern (usually HR and arterial BP reactivity) coined as the cardiac defense response (CDR). The CDR indexes activity of the defensive motivational system and behavioral coping programs. Using the CDR as a model of defensive behavior, the aim was to analyze putative contribution of brain oscillations into central mechanisms of enhanced cardiovascular stress reactivity in arterial hypertension patients. To address this issue the CDR was elicited in controls (n=19) and naive unmedicated hypertensives (n=17). Heart rate (HR) and arterial blood pressure (BP), based on the beat-by-beat technology (Finometer®) along with 64-channel EEG were simultaneously recorded while the 3 CDR were sequentially evoked. As for the neurophysiological analysis of the CDR’s time-course the event-related synchronization/desynchronization (ERD/ERS) of EEG in different frequency bands was calculated throughout the all recorded CDRs. It was revealed that long-latency BP increases in hypertensives were marked by lack of the alpha-2 (10-12 Hz) ERS over the central and centro-parietal cortex bilaterally. On the contrary, the controls manifested alpha-2 ERS over these regions which was concomitant to the lowered long-latency BP reactivity. High frequency brain alpha oscillations of the centro-parietal cortex are involved into the top-down inhibitory control of BP stress reactivity, and arterial hypertension may be associated with the deficiency of this mechanism.
COMPARATIVE NEUROPHYSIOLOGICAL ANALYSIS OF THE SUPPORT AND USEFUL ADJUSTING RESULT: LOGIC AND FACTS
Authors: Zhuravlev B V
Published: October 2016

In the article the physiological principles and processes are stated from the point of view of the theory of functional systems of the academician P. K. Anokhin. On the basis of development of these representations, and also received experimental dates the concept about result as system-organization factor is offered. Useful adaptation effect determinate physiological process occurring in the central nervous system of the basis of feed back afferents about parameters of result of action to the neurons included in structure of the towards model of results of action. The logic and experimental dates of representation about result at a regulation of blood pressure level, feed behavior and social form of activity of the man are given. Are considered neurophysiological processes at goal-directed activity of animal, underlying formations useful of result as «effect» in system (reinforcement).
ABOUT THE CONNECTION BETWEEN VEGETATIVE NERVOUS SYSTEM TONUS AND FUNCTIONAL INTERHEMISPHERIC BRAIN ASYMMETRY AMONG PUPILS DEPRIVED OF HEARING
Authors: Akulina M V , Endolov V V
Published: October 2016

121 pupils of specialized boarding school for deaf children and children with poor hearing were examined. While the four year research of vegetative nervous system (VNS) tonus and individual display of functional interhemispheric brain asymmetry it was found out that the adaptation of deaf pupils and pupils with poor hearing happens with higher tonus of sympathetic section of vegetative nervous system than among pupils with good hearing. It was also found the connection between VNS tension with interhemispheric brain asymmetry and hearing factor.
Characteristics of phylogenetically different parts of rats brain cortex after irradiation
Authors: Ilicheva V N , Ushakov B N
Published: October 2016

Morphofunctional changes in neocortex, archicortex and paleocortex were studied in experiment on white male rats after single and fractionized irradiation in a doze of 0,2 Gy. The comparison of morphometric parameters in the studied parts of brain was carried out.
OVERWEIGHT IN GIRLS IN THE FIRST YEAR OF LIFE, AS A RISK FACTOR OF OBESITY IN ADOLESCENCE
Authors: Grebova L P , Varvarina J P
Published: October 2016

The study of 55 adolescent girls with normal and 112 - are overweight. A retrospective analysis of the physical development of these girls, prospective analysis of the physical development of children in the first year of life. The influence of overweight girls' first year on the development and progression of obesity in adolescence.
PSYCHOLOGICAL STATUS AND ADAPTIVE RESOURSES PATIENTS WITH CANCER
Authors: Rusina N A
Published: October 2016

Psychological status and adaptive resources of patients with cancer was investigated. It was shown that oncological patients badly need special psychological correction according to their type of personality and adaptive resources. The correction can conclude training for emotional reactions, overcoming dependence on stereotypes of behavior and thinking and changing of self-conception, actualization of new personal senses.
CLINICAL, RADIOLOGICAL, AND MORPHOLOGICAL ASSESSMENT OF LATE RESULTS FOR REVASCULARIZATION OF THE FEMORAL HEAD AND NECK IN DEGENERATIVE AND DYSTROPHIC DISEASES OF THE HIP JOINT IN ADULTS
Authors: Nazarov E A , Papkov V G , Levitin A V , Musaeva R F
Published: October 2016

At assessment of 41 patients at late (7 to 26 years) terms after revascularization of the femoral head and neck, it was determined that 9 patients who underwent the surgery at the early, pre-radiological, stage of a vascular femoral head necrosis (AFHN) are healthy. In 18 patients who underwent the surgery at late terms of degenerative and dystrophic diseases of the hip joint (DDDHJ), worsening of the radiological picture was not associated with clinical progression of the disease. Histological investigation of the femoral heads showed that the vascular complex implanted into the head and neck of the femur functions for up to 22 years, and the lumen of the artery is patent, blood supply improves. The above mentioned, obviously, implies some favorable influence of this surgical intervention on the course of the pathological process.
TECHNIQUE-TECHNOLOGICAL ASPECTS OF PHARMACEUTICAL ECONOMIC SAFETY
Authors: Kuznetsov D A
Published: October 2016

In this article considers a technique-technological component of pharmaceutical economic safety. On the basis of a principle subsidiarity the system of a quantitative estimation of technique-technological making economic safety of the pharmaceutical organization, a matrix of security of technique-technological safety is offered. In work major factors of a technique-technological component are studied, value of weight factors with use of methods of the theory of fuzzy sets are established.
SURGICAL TREATMENT OF SIMPLE CYSTS OF A NEPHRITIC PARENCHYMA: THE LITERATURE REVIEW
Authors: Cherenkov A A
Published: October 2016

In article presented the short review of the special literature, concerning problems of a choice of an optimum way of surgical treatment of simple cysts of kidneys.
INFECTIOUS MORBIDITY IN THE SYSTEM OF SOCIAL-HYGIENIC MONITORING
Authors: Abramova A O
Published: October 2016

The literature review on the place and the role of the indices of infectious morbidity of population in the system of social-hygienic monitoring and influence of infectious morbidity on the population health and demographic processes has been shown in the article. Possibility of the risk assessment of infectious morbidity as one of the indices of the module “Health” in the system of social-hygienic monitoring has been discussed.
DESCRIPTION OF VARIOUS PHYLOGENETIC RELATIONSHIPS IN CORTICAL RAT
Authors: Il'icheva V N , Ushakov B N
Published: October 2016

Morphofunctional changes in neocortex, archicortex and paleocortex were studied in experiments on male rats after a single exposure to doses of 0,5 and 1,0 Gy. It was founded that the severity of changes and time of onset of compensatory responses in the alterative changed nerve cells depend on the dose and time after exposure, and the phylogenetic age of the cortex.
THE CHANGES IN THE SYNTHESIS OF PROTEINS OF PREGNANCY IN SOME CLINICAL MANIFESTATIONS OF UTEROPLACENTAL INSUFFICIENCY
Authors: Chikin V G , Pchelintsev V V
Published: October 2016

Miscarriage and fetal growth retardation which cause alterations in the protein synthesis function of the uteroplacental complex occupy one of the leading positions in the structure of causes of perinatal and child morbidity and mortality. Investigation of the dynamics of TBG, AMGF, PAMG levels during treatment of uteroplacental insufficiency was conducted. The changes revealed in the protein synthesis indicate dysaptation, which is more evident if there is fetal growth retardation than if there is threatened miscarriage.
ESTIMATION OF CONDITION THE CIRCULATE ERYTHROCYTES AT ILEOCYSTOPLASTY WITH APPLICATION EPIDURAL ANESTHESIA
Authors: Sharipov R A , Mironov P I
Published: October 2016

The aim-study is to be estimation of metabolic and structural particularly erythrocytes with application epidural anesthesia carring out Studer ileocystoplasty. Study design - prospective, nonrandomized, controlled. In study enrolled 100 patients. It was shown that the of metabolic and structural change of erythrocytes may be corrected with application epidural anesthesia at perioperation period.
ACTION OF COURSE LOVASTATIN APPLICATION ON ACTIVITY OF LYSOSOMAL ENZIMES IN EXPERIMENT
Authors: Polupanov A S , Yakusheva E N , Uzbekova D G
Published: October 2016

Paper shows that course application of lovastatin in rats increase nonsedimenteted activity of lysosomal katepsin D and DNA-aze in liver and skeletal muscle. After cancelation of lovastatin therapy investigated indicators will be going to normal level.
THE TOXIC ACTION OF METAL COMPOUNDS ON THE FUNCTION OF DIGESTION AT DIFFERENT ROUTES OF ENTRY
Authors: Zdolnik T D
Published: October 2016

The results of studying the toxic action of soluble compounds of metals - zinc, lead, chromium, molybdenum and tungsten on the function of digestion after oral and parenteral admission has been presented in the article. Comparative toxicity of metal compounds on the function of digestion has been established. It has been shown that the dependence of the character and strength of the studied effect of the route of entry of metal compounds is determined by the value of their gastro-intestinal absorption and the degree of their removal from the organism through the digestive system.
FUNCTIONAL STATE WORKERS EMPLOYED RECYCLING LEAD USING DIFFERENT TECHNOLOGIES
Authors: Chudinin N V , Kiryushin V A , Bolchakov A M
Published: October 2016

In-depth study of the working conditions of workers employed in different ways of processing of secondary lead, allowed a comparative assessment of labor conditions and to assess the impact of the production process for the voltage of the functional state of the cardiovascular system in the dynamics of the work.
ASSESSMENT OF THE HEALTH OF WORKERS ACCORDING TO THE COMPUTER DIAGNOSTIC SYSTEM
Authors: Kharitonov V I
Published: October 2016

This article sets out the results of the survey and evaluation of the health of workers obtained using an automated screening system for quantification of the risk of major pathological syndromes. The system is based on a mathematical algorithm to divide the survey on quantitative measures of risk of major pathological syndromes for further examinations and further examination. Shows the availability of the methodology of the survey in the real production under the direction of a physician in the practice of bulk plant preventive examinations. Identified high prevalence risk of obŝepatologičeskih syndromes, reflecting the extreme nature of the conditions.
METAPLASIA OF GASTRIC MUCOSA IN A HISTORICAL ASPECT: FROM KUPFFER’S AND VIRCHOW’S VIEWS TO CONTEMPORANEITY
Authors: Vernygorodskyi S V
Published: October 2016

In article the formation of views on the problem of gastric mucosa metaplasia in historical aspect - from Kupffer’s and Virchow’s proceedings to contemporaneity was studied on the basis of literature and own observations analysis.
MEDICO-SOCIAL ASPECTS OF PREVALENCE OF SEXUAL TRANSMITTED INFECTIONS (RYAZAN REGION MATERIALS)
Authors: Zhiltsova E E
Published: October 2016

In article analyses the indicators by the basic sexual transmitted infections and its structure in 2006-2010 on an example of the Ryazan region. Features of STI prevalence in area are shown.
THE LIFE QUALITY OF PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE COMBINED WITH ISCHEMIC HEART DISEASE
Authors: Koubaji K , Maghraoui W , Rackita D R , Solovjeva A V
Published: October 2016

In this article are studied quality of life, clinical and functional indicators of patients with chronic obstructive pulmonary disease (COPD) and associated coronary heart disease (CHD) « stable angina, FO II ». Surveyed 23 persons with CHD and 74 persons with COPD “stages I-III” including 39 persons with accompanying CHD. It revealed that the patients with association of COPD and CHD have a lowered physical and psychological elements of life quality.
STUDY OF SYSTEMIC INFLAMMATION IN PATIENTS BRONCHIAL ASTHMA IN COMBINATION WITH METABOLIC SYNDROME
Authors: Sysoeva M S , Solovieva A V , Nikiforova L V , Rakita D R
Published: October 2016

In order to study the systemic inflammation in patients with associated pathology a survey included 48 patients with bronchial asthma, 34 of them were diagnosed with metabolic syndrome, had been performed. In patients with bronchial asthma in association with metabolic syndrome systemic inflammation was more expressed in comparison with patients without metabolic syndrome. An inverse relation between the parameters of respiratory function and C-reactive protein level had been revealed, and it’s concentration increased with the degree of abdominal obesity, severity of atherogenic disorders, fasting glucose levels, with the presence of type 2 diabetes.
COMPARATIVE STRUCTURAL-FUNCTIONAL ORGANIZATION OF EPILEPTIC PATIENTS WITH DIFFERENT SEIZURE TYPES
Authors: Krivtsova A Y , Zhadnov V A
Published: October 2016

Recent decades have seen significant achievements in scientific research in various fields of epileptology. The tendency of modern neurophysiology is the study of the organization of the nervous processes in terms of the system. A variant of this approach is the theory of functional systems P.K. Anohina. Neurophysiological study was performed of 82 patients with partial, secondary and primary generalized seizure types. It was revealed that the functional structural organization of patients with epilepsy with different types of seizures is vary.
RESEARCHING OF CARBOHYDRATE STRUCTURE OF SOME FAMILY ASTERACEAE PLANTS
Authors: Botov A Y , Severin A P , Yatsuk V Y , Siplivaya L E
Published: October 2016

In this article we have presented the results of the carbohydrate composition (water-soluble polysaccharide complex and pectins) research of some Asteraceae family species. We have also determined qualitative and quantitative composition of water-soluble polysaccharide complex and pectins by means of physico-chemical methods. The possibility of expanding resource base has been shown for obtaining medicinal products. It has become possible through the introduction of new medicinal plants of Erigeron genus and integrated use of the genus Artemisia plants.
CORRECTION OF ENDOTHELIAL DYSFUNCTION: CURRENT STATUS OF THE PROBLEM (LITERATURE REVIEW)
Authors: Suchkov I A
Published: October 2016

The abstract represents major causes, consequences and methods of correction of endothelial dysfunction according to the data published in Russian and foreign literature.
ON REHABILITATION OF DRUG ADDICTS IN PREVENTING DRUG CRIME
Authors: Turovsky I V
Published: October 2016

The article deals with the legal aspects of teaching social rehabilitation of drug addicts in the system of crime prevention.
MODERN STATE OF THE PROBLEM IMPACTS MULTIPLE INTENSIVE LABOUR IN MEDICINE
Authors: Kharitonov V I
Published: October 2016

This article presents the theoretical and practical aspects of the problem of intensive labour medicine influences multifactorial. Is the need to take into account the quantitative contribution of factors with the concomitant action for predicting the degree of real professional risk injury and prioritization of proposed preventive measures. Shows the importance of experimental and industrial research to assess the composite factors of different nature on individual reactions.
EXPERIMENTAL VALIDATION OF A GEL BASED ON CHITOSAN ACETATE FOR THE TREATMENT OF BURNS
Authors: Pogorelov M V , Kalinkevich O V , Ivakhnyuk T V , Moskalenko F R , Bonchev S D , Danilchenko S N , Sklyar A M , Kalinkevich A N , Sikora V Z , Romanyuk A N
Published: October 2016

In the work in vivo test of the gel based on chitosan with additions of miramistin, methyluracil and ascorbic acid were performed. The gel was prepared by solution of 2% chitosan in 0.5% acetic acid during 24h with the subsequent filtration through the glass filter with the average pore size. To obtain the modified gels the above mentioned substances were added to the solution in the proper concentrations. In vivo investigations were conducted using laboratory male rats with the modeled burns of IIB degree, which were randomized in the control and experimental groups. The last 3 days after application of burns, twice a day the wound surface was treated with different modifications of chitosan-based gels. Histological study has shown the decrease of inflammation reaction and edema in biopsy material, acceleration of epithelization on the wound surface and decrease of wound repair terms by 2-3 days. Microbiological investigation revealed the high bacteriostatic action of chitosan gel against the most species of burn surface microflora, which allowed avoiding infectious complications.
THE PROBLEM OF THE PREVENTIVE MEASURES OF THE RAIL CAR BUILDING PLANT WORKERS‘ HEALTH DISORDER
Authors: Istomin A V , Sinoda V A , Shushkova T S , Ustyushin B V
Published: October 2016

The priority factors of the rail car building plant workers' health risk have been detected. The mordibility analysis has been carried out, the risks diseases have been determined. The integral assessment of the functional state of workers' organism has been given. Some hygienic recommendations to provide the safety work conditions and retain the workers’ health have been worked out.
THE CHARACTERISTISTICS OF ATMOSPHERE POLLUTION BY PRODUCTS OF AUTOMOBILE FUEL COMBUSTION IN THE TERRITORY OF THE ASTRAKHAN REGION IN DYNAMICS FROM 2000 - 2009
Authors: Romankova J N
Published: October 2016

An investigation of atmosphere pollution by products of automobile fuel combustion was carried on in the Astrakhan region in dynamics from 2000 to 2009. As a result statistically factual stature of unhealthy chemical substances was uncovered. Most chemical substances concentration, possessing action summatsiya, exceeded 1,0 (unit) throughout the entire period of observation. The atmosphere pollution index was characterized as high since 2003.
THE SYSTEM OF QUALITY CONTROL OF RENDERING OF MEDICAL CARE IN A MULTI-FUNCTIONAL MEDICAL-PREVENTIVE INSTITUTION
Authors: Anichenko P N , Chirkov V A
Published: October 2016

This article describes one of the most effective forms of management of a modern medical institution - a meeting on the organization of management and quality of medical aid. The meeting is held once in a quarter for the improvement of management quality, better continuity between the departments, the organization of the activities of the organization in accordance with the requirements of standards ISO of a series 9001 and is an effective tool for transformation, significantly improves the performance of a medical institution, as well as allow superior integration of the individual processes in a single system.
IDENTIFICATION HERPES INFECTION, RUBELLA VIRUS IN THE FETUS AND NEWBORN WITH MALFORMATIONS AND SIGNS OF INTRAUTERINE INFECTION
Authors: Repina I B , Feklisova L V , Kalugina M U , Klochkov S A
Published: October 2016

The examination of smears prints 79 dead fetuses, miscarriages, babies with abnormalities and signs of intrauterine infection in order to determine the frequency of infection with herpes viruses: human herpes virus type 6 (HHV-6), cytomegalovirus (CMV), Epstein-Barr virus (EBV) and rubella virus clarify features of current ante- and neonatal period, causes of death, the definition of histological markers of intrauterine infection.
APPROACHES TO FORMATION OF DIFFERENTIAL CAPITATION IN THE STATUTORY HEALTH INSURANCE
Authors: Artemeva G B , Hecht I A
Published: October 2016

Modernization of the system of obligatory medical insurance within realization of “Obligatory medical insurance in Russian Federation” law presupposes the usage of graded per capital normatives for the calculation of local obligatory medical insurance programs financing. For the purpose, apart from sex-age coefficients of medical care consumption, it is supposed to use additional indicators characterizing the level of health (sickness rate, mortality, primary disablement) and also such indicators as sanitary-epidemiological and ecological wellbeing of the local areas and the level of medical care availability.
FREE RADICAL STATUS OF IRIDOCILIARY COMPLEX AND EYE AQUEOUS HUMOR IN EXPERIMENTAL CATARACT WITHOUT TREATMENT AND ON THE BACKGROUND OF IONOL SOLUTION LOCAL THERAPY
Authors: Kolesnikov A V
Published: October 2016

In experimental cataract, free radical status of iridociliary complex and of aqueous humor has been studied along with the effect of local application of the direct ionol antioxidant. Experimental cataract was induced by introduction of diquat-dibromide into the vitreous body. The development of cataract was accompanied by POL activation and sharp depression of antioxidant protection with spontaneous normalization of all biochemical indices by the 14-th experimental day. POL activation in the aqueous humor was observed over the whole experimental period, but antioxidant enzymes were not revealed with the techniques applied. Local application of ionol resulted in POL slowing-down in the aqueous humor, which indicates pathogenic tendency of its action in cataract.
RHINOSEPTOPLASTY PERFORMED FOR POSTTRAUMATIC COMBINED NOSE DEFORMITY IN THE FORM OF RHINOSCOLIOSIS, LORDOSIS AND KIFOSIS
Authors: Medvedev V A
Published: October 2016

The article deals with the technologies of rhinoplasty applaid in the case of the combined nose deformity in the form of rhinoscoliosis with rhinolordosis and kifosis. The distinguishing features of rhinoplasty performed for the nose deformity in the form of rhinoscoliosis with rhinolordosis and kifosis are those that the removal of nasal hump is performed with help of a special directing instrument used for the endonasal removal of hump. The instrument for mobilization of nasal bones us also used. It help to mobilize, narrow and give middle position to the nasal back. The cartilage implant felling the fall of the nasal back is fixed in the place of its fall. The technologically peculiarities of performing rhinoseptoplasty described in the article let us avoid recurrent nose deformities.