bluuebunny/crossref_metadata_2025 huggingface dataset:
Foliar applications to vines of methyl jasmonate and nanoparticles doped with methyl jasmonate: impact on grape and wine polysaccharide composition
Authors: Martínez-Lapuente Leticia , Garde-Cerdan Teresa , Pérez-Álvarez Eva P. , Guadalupe Zenaida , Parra-Torrejón Belén , Ayestarán Belén
Published: January 2023

Polysaccharides in wine play important roles in the stabilization and in the sensory properties of wines. Elicitor application constitutes an interesting field of research since it is indirectly involved in the accumulation in grape cell walls of molecules like callose, lignin, phenolic compounds and glycoproteins. Currently, biomimetic calcium phosphate (ACP) nanoparticles are successfully used in viticulture for the controlled delivery of bioactive molecules, such as elicitors. The aim of this study was to compare the effect of the application of two different elicitors on both grape and wine of Tempranillo polysaccharide composition. Methyl jasmonate (MeJ) and nanoparticles doped with MeJ were applied to the canopy at veraison and one week later in two vintages. In the grape extracts, the foliar treatments did not increase the content of monosaccharides or that of the main pectin families; therefore, the elicitors did not reinforce the cell walls of the Tempranillo grape. The extractability and solubility of the pectic families of the grape cell walls into the wine depended on the type of family and the climate of the vintages.
The Relationship between Motivation for Achievement and Reasoning with Teacher Work Performance
Authors: Nur Farihin , Syamsi Atikah
Published: January 2023

The purpose of this study is to reveal whether or not there is a relationship and the strong relationship between teacher achievement motivation and teacher work performance, to reveal whether or not there is a relationship and the strong relationship between teacher reasoning abilities and teacher work performance. The population in this study were all teachers at MA in Indramayu district totaling 155 respondents with 30 respondents. The results showed that there was a positive relationship between achievement motivation and teacher work performance. Both go hand in hand, meaning that the higher the achievement motivation, the higher the teacher's work performance. Thus, the contribution of this study includes nopositive relationship between reasoning ability and teacher work performance. There is a positive relationship between achievement motivation and reasoning ability with teacher work achievement. The two independent variables go hand in hand with the dependent variable, the higher the teacher's work performance. 

 

Hubungan Motivasi Berprestasi dan Penalaran dengan Prestasi Kerja Guru. Tujuan penelitian ini adalah untuk mengungkapkan ada atau tidaknya sebuah hubungan, dan seberapa kuat hubungan antara motivasi prestasi guru dengan prestasi kerja guru, untuk mengungkapkan ada hubungan atau tidaknya dan hubungan yang kuat antara kemampuan penalaran guru dengan prestasi kerja guru. Populasi dalam penelitian ini adalah seluruh guru di MA di kabupaten Indramayu yang berjumlah 155 responden dengan 30 responden. Hasil penelitian menunjukkan bahwa terdapat hubungan positif antara motivasi berprestasi dengan prestasi kerja guru. Keduanya berjalan beriringan, artinya semakin tinggi motivasi berprestasi, semakin tinggi prestasi kerja guru. Dengan demikian kontribusi penelitian ini antara lain tidak ada hubungan positif antara kemampuan penalaran dengan prestasi kerja guru. Terdapat hubungan positif antara motivasi prestasi dan kemampuan penalaran dengan prestasi kerja guru. Kedua variabel independen berjalan beriringan dengan variabel dependen, semakin tinggi prestasi kerja guru.
Kesadaran Masyarakat Kecamatan Sumowono Kabupaten Semarang Terhadap Hukum Kewarisan Islam
Authors: Maskuri Erkham , Sriani Endang
Published: January 2023

The purpose of this research is to describe the level of public awareness in Sumowono District, Semarang Regency regarding Islamic inheritance law and its problems. This research is a qualitative Field Research with a deeper understanding of the facts or phenomena that arise and occur in the research object. The data were obtained through in-depth interviews with nine key figures in the Sumowono District, then an analysis was carried out by reducing irrelevant data, presenting the findings in the field and drawing conclusions. The results of this study indicate that the knowledge of the community in Sumowono District, Semarang Regency about Islamic inheritance law is relatively low, there are still facts about inheritance distribution that are not in accordance with the rules of Islamic inheritance law. This arises because there is still a lack of legal awareness in the community to carry out inheritance distribution according to Islamic inheritance law and the government and religious leaders have not maximized counseling.

Tujuan dari penelitian ini adalah untuk mendeskripsikan tingkat kesadaran masyarakat Kecamatan Sumowono, Kabupaten Semarang terhadap hukum kewarisn Islam dan problematikanya. Penelitian ini merupakan Field Research kualitatif dengan memahami lebih mendalam kenyataan atau fenomena yang muncul dan terjadi pada objek penelitian. Data diperoleh melalui wawancara mendalam dengan sembilan tokoh kunci di Kecamatan Sumowono kemudian dilakukan analisis dengan mereduksi data yang tidak memiliki relevansi, memaparkan data temuan di lapangan dan membuat kesimpulan. Hasil dari penelitian ini menunjukkan bahwa pengetahuan masyarakat di Kecamatan Sumowono Kabupaten Semarang tentang hukum kewarisan Islam terbilang rendah, masih ditemukan fakta pembagian warisan yang tidak sesuai dengan aturan-aturan hukum Kewarisan Islam. Hal itu muncul karena masih minimnya kesadaran hukum pada masyarakat untuk menjalankan pembagian waris sesuai hukum kewarisan Islam dan belum maksimalnya penyuluhan oleh pemerintah dan tokoh agama.
Implementation of Social Assistance In Communities Affected by The Covid-19 Pandemic In Penawangan District Grobogan Regency Maqasid Al-Syariah Perspective
Authors: Hisam Luqman Nur
Published: January 2023

One form of government attention to the people affected by the Covid-19 Pandemic is by providing social assistance. The provision of social assistance is intended as an effort by the government to support community needs and restore health and nutrition. This study aims to examine and analyze the effectiveness of the distribution of social assistance to the community in Penawangan District, Grobogan Regency and examine it from the perspective of maqasid al-syariah. The type of method used in this study is sociological juridical with a qualitative approach. The main data sources were obtained through observation and interviews with informants, while the secondary data sources used books and articles. The data and information obtained were then processed using data analysis techniques in the form of descriptive qualitative. The conclusions of this study indicate that the distribution of social assistance has not been fully effective and fair because some of the assistance provided is not on target. Furthermore, when viewed from the maqasid al-syariah provision of social assistance by the government to the community can be said to be of benefit because it can preserve the soul (hifdz an-nafs) and restore the economy of the people affected by the Covid-19 pandemic in Penawangan District Grobogan Regency.

Salah satu bentuk perhatian pemerintah terhadap masyarakat terdampak Pandemi Covid-19 yaitu dengan memberikan bantuan sosial. Pemberian bantuan sosial ini dimaksudkan sebagai upaya pemerintah guna menopang kebutuhan masyarakat serta pemulihan kesehatan dan gizi. Penelitian ini bertujuan untuk menelaah dan menganalisis efektivitas pendistribusian bantuan sosial pada masyarakat di Kecamatan Penawangan Kabupaten Grobogan serta mengkajinya dalam perspektif maqasid al-syariah. Jenis metode yang digunakan dalam penelitian ini adalah yuridis sosiologis dengan pendekatan kualitatif. Sumber data utama diperoleh melalui observasi dan wawancara dengan para informan, sedangkan sumber data sekunder menggunakan buku dan artikel. Data dan informasi yang diperoleh selanjutnya diolah dengan teknik analisis data berupa deskriptif kualitatif. Hasil kesimpulan penelitian ini menunjukkan bahwa pendistribusian bantuan sosial belum sepenuhnya berjalan efektif dan adil sebab beberapa bantuan yang diberikan tidak tepat sasaran. Selanjutnya apabila ditinjau dari perspektif maqasid al-syariah terhadap pemberian bantuan sosial oleh pemerintah kepada masyarakat dapat dikatakan bernilai kemaslahatan sebab dapat memelihara jiwa (hifdz an-nafs) dan pemulihan ekonomi masyarakat terdampak pandemi Covid-19 di Kecamatan Penawangan Kabupaten Grobogan.
HUMAN CAPITAL AND ECONOMIC DEVELOPMENT: BELARUS AND NEIGHBOR COUNTRIES
Authors: Shebeko K. , Groshev V. , Shabeka. D.
Published: January 2023

Based on the synthesis of cardinalist and ordinalist approaches to measuring economic processes and phenomena and based on the data of 167 countries for 2020 year, we performed the analysis of the relationship between the indicator of GDP per capita, PPP (current international $) and the human capital index. The results of the analysis show that Belarus and Ukraine have higher potential for economic development in comparison with other analyzed countries due to the accumulated level of human capital. Ceteris paribus, due to the accumulated level of human capital in these two countries, it is possible to increase GDP per capita at PPP in current prices in international dollars by 89,4 % and 127,4 %, respectively.
A NEW THEORETICAL AND METHODOLOGICAL APPROACH TO SOCIAL ENTREPRENEURSHIP IN THE CONTEXT OF NATIONAL SECURITY
Authors: Popkova. A.
Published: January 2023

Based on the works of the leading researches, authoritative methodological approaches to social entrepreneurship are analyzed: the blended value, social capital theory, the stakeholder theory, the positive theory of social entrepreneurship, etc. It is revealed that one of the main problems in the interpretation of social entrepreneurship is the dichotomy between economic and social values. The result of the research is a new theoretical and methodological approach to social entrepreneurship based on positive social amplification. This approach promotes the national security interests and allows ensuring the national security criteria of the state
Análisis de máxima tensión compresiva en incisivos centrales superiores rehabilitados con postes de fibra de vidrio y tres tipos de coronas. Método de elementos finitos.
Authors:   , Chávez Vela Mayra Jannina
Published: January 2023

OBJETIVO: Evaluar la máxima tensión compresiva en incisivos centrales superiores restaurados con postes de fibra de vidrio y tres tipos de coronas por método de elementos finitos MEF. MATERIALES Y MÉTODOS: el estudio fue un ensayo de laboratorio virtual, descriptivo y transversal. Se confeccionaron 3 modelos virtuales mediante el programa computarizado Software Solid Works 2017 a partir de incisivos centrales superiores rehabilitados con postes de fibra de vidrio y corona metal-cerámica, corona de disilicato de litio monolítica y corona de zirconio-cerámica; luego fueron sometidos a una carga oclusal oblicua de 150N con angulación de 45°, distribuida hacia la cara palatina. El análisis de las tensiones se procedió mediante la comparación de las tensiones máximas, minimas y equivalentes de Von Mises. RESULTADOS: La máxima tensión compresiva se encontró a nivel cervical en la zona vestibular de cada una de las coronas; siendo el diseño 3 corona de zirconio-cerámica la que presentó mayor tensión compresiva con 73.89 MPa, seguido de los diseños 2 corona de disilicato de litio con 63.42 MPa y diseño 1 corona metal-cerámica con 48.4 MPa. CONCLUSIÓN: La corona zirconio cerámica generó la máxima tensión compresiva especialmente en la zona cervical del diente, a diferencia de las otras coronas disilicato de litio monolítico y metal cerámica estudiadas; esto probablemente debido a la mayor rigidez que posee según el módulo elástico.
In-silico identification of phytocompounds as inhibitors to two key enzymes of Shikimate pathway of Mycobacterium tuberculosis for discovery of new lead molecule(s) for treatment of Tuberculosis.
Authors: Sarkar Narayan , Tanti Bhaben , Bharali Suresh , Mahanta Saurov
Published: January 2023

Tuberculosis(TB) is one of the most lethal respiratory infections caused by the organism Mycobacterium tuberculosis. Several drugs are available for the treatment of TB. Numerous reports have demonstrated the cause and emergence of multi drug resistance of M. tuberculosis. To improve the treatment of these strains , there is rising need to develop anti-TB effective drugs. The aim of this research was to develop an anti-tuberculosis drug.The two enymes 3-Dehydroquinate synthase(3N76) and 3-dehydroquinate dehydratase(3QBE) , of mycobacterial shikimate pathway was selected as drug targets.The structures of these two enzymes were obtained from PDB data bank.The phytocompounds from a medicinal plant,which was traditionally used in pulmonary infection, Achyranthes aspera ,were selected as ligands .Molecular docking was done against these two enzymes(receptors) by 11 phytocompounds of Achyranthes aspera by AUTODOCK vina software. The compounds which have highest binding affinity with targets was selected. Later pharmacokinetic analysis, bioactivity prediction, toxicity calculation of these compounds was done.From the docking study, the compound9(Ecdysterone 2,3-acetonide 22-O-benzoate), has highest binding affinity with enzyme 3-dehydroquinate synthase(3N76), And the compound 2(2,3,14,20,25-Pentahydroxy-6-oxocholest-7-en-22-yl benzoate) has highest binding affinity with enzyme 3-dehydroquinate dehydratase(3QBE).The druglikeness of these two compounds shows that both of them obey Lipinski’s rule of 5.
Burden of diabetes mellitus type 2 and its risk factors in Asia from 1990 to 2019: Updates from the 2019 Global Burden of Disease study
Authors: khazaei zaher , Momenabadi Victoria , Badrizadeh Afsaneh , Pordanjani Sajjad Rahimi , goodarzi elham
Published: January 2023

BackgroundThe mounting burden of type 2 diabetes is a major concern in healthcare systems worldwide. The purpose of this study is to investigate the trend of type 2 diabetes from 1990 to 2019 in Asia.MethodsAll accessible data from the 2019 Global Burden of Disease study were used to estimate the diabetes mellitus type 2 prevalence, mortality and disability-adjusted life years and diabetes mellitus type 2 in Asia from 1990 to 2019. We estimated all-cause and cause-specific mortality, years of life lost (YLLs), years lived with disability (YLDs), disability-adjusted life-years (DALYs) and attributable risk.ResultsThe results indicated that the human development index (HID) was positively and significantly correlated with the incidence of type 2 diabetes in men (r = 0.481, P<0.05) and women (r=0.414, P<0.05, but the correlation between death and the HDI was not significant in men and women (P> 0.05). The highest share of DALY risk factors in men (12093.2 per 100000) and in women (7122.4 per 100000) was related to behavioral factors. According to the results, air pollution, high fasting plasma glucose, and dietary risks are the main risk factors associated with the burden of type 2 diabetes in women and men, respectively.ConclusionGiven that the burden of type 2 diabetes is escalating in Asia and the burden of disease can be largely controlled by managing its risk factors, the disease management program in different countries, especially in countries with high prevalence and high burden could be reduced by making policies.
Cognitive retraining and functional treatment (CRAFT) for adults with cancer related cognitive impairment: A randomized controlled trial
Authors: Maeir Talia , Makranz Chen , Peretz Tamar , Odem Ester , Tsabari Shani , Nahum Mor , Gilboa Yafit
Published: January 2023

Purpose: To examine the applicability and efficacy of Cognitive Retraining and Functional Treatment (CRAFT) combining remote computerized cognitive training (CCT) and occupation-based treatment in adults with cancer-related cognitive impairment (CRCI).
Methods: Three-armed randomized controlled trial including 74 individuals with CRCI, randomized into 12 weeks of either CRAFT, CCT alone, or treatment-as-usual. Assessments evaluating participation in daily life, perceived cognition, cognitive performance, quality-of-life, and treatment satisfaction were administered at baseline, post-intervention and 3-month follow up.
Results: Significant time X group interactions in favor of the CRAFT and CCT groups were found for participation in daily life (F2,34=5.31, p=.01, eta=.238), perceived cognition (F2,34=4.897, p=.014, eta=.224) and cognitive performance on speed of processing test (F=5.678, p=.009, eta=.289). CRAFT group demonstrated significantly larger clinically meaningful gains on participation in daily life (Chi-square= 6.91, p=.032) and significantly higher treatment satisfaction. All treatment gains were maintained at a 3-month follow-up (n=32).
Conclusions: CCT and CRAFT were found to have a positive impact on participation and cognitive outcomes among individuals with CRCI. The CRAFT showed an additional advantage in improving self-chosen occupation-based goals suggesting that a combination of cognitive training with occupation-based intervention has a positive synergistic effect resulting in ‘real world’ health benefits.
Implications for Cancer Survivors: A combination of cognitive training with occupation-based intervention has a positive effect resulting in clinically meaningful improvements in participation in daily life, objective cognitive performance, and subjective cognitive impairment.
Clinical Trial Registration: ClinicalTrials.gov NCT04210778, December 26, 2019, retrospectively registered.
Serum- and xeno-free culture of human umbilical cord perivascular cells for pediatric heart valve tissue engineering
Authors: Nejad Shouka Parvin , Lecce Monica , Mirani Bahram , Siqueira Nataly Machado , Mirzaei Zahra , Santerre J. Paul , Davies John E. , Simmons Craig
Published: January 2023

Background: Constructs currently used to repair or replace congenitally diseased pediatric heart valves lack a viable cell population capable of functional adaptation in situ, necessitating repeated surgical intervention. Heart valve tissue engineering (HVTE) can address these limitations by producing functional living tissue in vitro that holds the potential for somatic growth and remodelling upon implantation. However, clinical translation of HVTE strategies requires an appropriate source of autologous cells that can be non-invasively harvested from MSC-rich tissues and cultured under serum- and xeno-free conditions. To this end, we evaluated human umbilical cord perivascular cells (hUCPVCs) as a promising cell source for in vitro production of engineered heart valve tissue.
Methods:The proliferative, clonogenic, multilineage differentiation, and extracellular matrix (ECM) synthesis capacities of hUCPVCs were evaluated in a commercial serum- and xeno-free culture medium (StemMACS™) on tissue culture polystyrene and benchmarked to adult bone marrow-derived MSCs (BMMSCs). Additionally, the ECM synthesis potential of hUCPVCs was evaluated when cultured on polycarbonate polyurethane anisotropic electrospun scaffolds, a representative biomaterial for in vitro HVTE.
Results:hUCPVCs had greater proliferative and clonogenic potential than BMMSCs in StemMACS™ (p<0.05), without differentiation to osteogenic and adipogenic phenotypes associated with valve pathology. Furthermore, hUCPVCs cultured with StemMACS™ on tissue culture plastic for 14 days synthesized significantly more total collagen, elastin, and sulfated proteoglycans (p<0.05), the ECM constituents of the native valve, than BMMSCs. Finally, hUCPVCs retained their ECM synthesizing capacity after 14 and 21 days in culture on anisotropic electrospun scaffolds.
Conclusion:Overall, our findings establish an in vitro culture platform that uses hUCPVCs as a readily-available and non-invasively sourced autologous cell population and a commercial serum- and xeno-free culture medium to increase the translational potential of future pediatric HVTE strategies.
Machine Learning to Develop a Predictive Model of Pressure Injury in Persons with Spinal Cord Injury
Authors: Luther Stephen , Thomason Susan , Sabwarhal Sunil , Finch Dezon , McCart James , Toyinbo Peter , Bouayad Lina , Lapcevic William , Hahm Bridget , Hauser Ronald , Mathney Michael , Powell-Cope Gail
Published: January 2023

Study Design: A 5-year longitudinal, retrospective, cohort study.
Objectives: Develop a prediction model based on electronic health record (EHR) data to identify veterans with spinal cord injury/diseases (SCI/D) at highest risk for new pressure injuries (PIs).
Setting: Structured (coded) and text EHR data, for veterans with SCI/D treated in a VHA SCI/D Center between October 1, 2008, and September 30, 2013.
Methods: A total of 4,709 veterans were available for analysis after randomly selecting 175 to act as a validation (gold standard) sample. Machine learning models were created using ten-fold cross validation and three techniques: 1) two-step logistic regression; 2) regression model employing adaptive LASSO; 3) and gradient boosting. Models based on each method were compared using area under the receiver-operating curve (AUC) analysis.
Results: The AUC value for the gradient boosting model was 0.62 (95% CI = 0.54-0.70), for the logistic regression model was 0.67 (95% CI = 0.59-0.75), and for the adaptive LASSO model was 0.72 (95% CI = 0.65-80). Based on these results, the adaptive LASSO model chosen for interpretation. The strongest predictors of new PI cases were having fewer total days in the hospital in the year before the annual exam, being in the highest vs. lower weight categories and most severe vs. less severe grade of injury based on the American Spinal Cord Injury Association (ASIA) Impairment Scale.
Conclusions: While the analyses resulted in a potentially useful predictive model, clinical implications were limited because modifiable risk factors were absent in the models.
Facile synthesis of efficient MoS2 coupled graphitic carbon nitride heterojunction nanocomposites: Photocatalytic removal of methylene blue dye under solar light irradiation
Authors: Krishnasamy Mahalakshmi , Rajendran Ranjith , Shanmugam Vignesh , Arumugam Priyadharsan , Barathi Diravidamani , Mohd Shkir , Hamed Algarni
Published: January 2023

Among different types of semiconductor photocatalysts, MoS2 hybridized with graphitic carbon heterojunction has developed the most promising “celebrity” due to its static chemical properties, suitable band structure, and facile synthesis. Physiochemical and surface characterizations were revealed with XRD, SEM, TEM, DRS, and FTIR analysis. DRS evidenced the energy band gap tailoring from 2.62 eV for pure g-C3N4 and 1.68 eV for MoS2 to 2.12 eV for the hybridized heterojunction nanocomposite. Effective electron/hole pair separation, rise in redox species and great utilization of solar range because of band gap modifying leading to greater degradation efficacy of g-C3N4/MoS2 heterojunction. The photocatalytic degradation with MoS2/g-C3N4 heterojunction catalyst to remove methylene blue dye was enriched surprisingly which was much higher in comparison with g-C3N4. By carefully examining the stimulus aspects, a probable mechanism is suggested, assuming that the concurring influence of MoS2 and g-C3N4, the lesser crystallite size, and more solubility in aquatic solution furnish the efficient e− - h+ pairs separation and tremendous photocatalytic degradation activity. This work delivers a novel idea to improve the efficient MoS2/g-C3N4 heterojunction for improved photocatalytic degradation in environmental refinement.
Detection of Microcystins in South African surface waters by high performance liquid chromatography in the light of Quality by Design statical tool.
Authors: Mthembu Zama , Govender Hogantharanni , Hendricks Nokwanda , Omotola Elizabeth Oyinkansola , Kowtharapu Leela Prasad , Katari Naresh Kumar , Gumbi Bhekumuzi
Published: January 2023

Cyanobacteria, an algae bloom that is responsible for the creation of deadly toxins. These toxins have the potential to adversely impact human and animal health. Microcystins (MC’s), are harmful toxins that are produced by cyanobacteria species. These deadly toxins are the most investigated toxins worldwide. However, in South Africa their occurrence statistics are deficient due to inaccessibility of reliable, sensitive, and precise analytical methods to investigate them in water surfaces. Thus, a development of analytical methods for the detection and accurate quantification of algal toxins is crucial to consider the health risk of exposure to toxins in wastewater and surface waters. This study recommends an analytical method for the detection and quantification of algal toxins using solid phase extraction (SPE) and high-performance liquid chromatography (HPLC) coupled with photodiode detector (PDA). The developed method was validated based on linearity which ranged from 3–2500 µg L− 1, recoveries at 99.6–113.9%, the limit of detection (LOD) ranging from 0.2–480 µg L− 1, and limit of quantification (LOQ) at 0.7–160 µg L− 1 and the regression coefficients obtained were above 0.9880 in all analytes. The developed method was applied to Darvill Wastewater Treatment Plant, Umgeni water, Durban surface waters, University of KwaZulu-Natal (UKZN) sport centre tap water and UKZN Westville two ponds), South Africa. MC-RR was the most detected analyte at concentration ranging from 0.069–30.521 ng L− 1 compared to other targeted MCs. The developed method is simple and cheap, which can consent developing countries to monitor these deadly MC toxins in water surfaces.
Construction of ZnIn2S4/MOF-525 heterojunction system to enhance photocatalytic degradation of tetracycline
Authors: Zhang Xiansheng , Liu zhifeng , Shao Binbin , Wu Ting , Pan Yuan , Luo Songhao , He Miao , Ge Lin , Sun Jingwen , Cheng Chunyun , Huang Jian
Published: January 2023

Zirconium-based porphyrin metal organic framework (Zr-PMOF) is considered as a promising photocatalytic material due to its large specific surface area, wide visible light absorption capacity, good water stability and chemical stability. However, the recombination of photogenerated carriers of monomer PMOF limits its performance of photocatalytic organic pollutants degradation. Metal sulfide has a suitable visible band gap, which can form a heterojunction with MOF materials to enhance the photocatalytic efficiency of MOF. Therefore, a typical metal sulfide semiconductor ZnIn2S4 (ZIS) is introduced into a Zr-MOF (MOF-525) by solvothermal method to prepare the ZIS/MOF-525 composite photocatalyst in this work. The results of characterization analysis, optical analysis and electrochemical analysis show that the interface of ZIS/MOF-525 forms a typical type-Ⅱ heterojunction, which accelerates the electron transport rate and effectively inhibits the recombination of photogenerated e- and h+ in MOF-525. The optimal removal efficiency of tetracycline (TC) by ZIS/MOF-525-3 can reach 93.8% under 60 min visible light illumination, which is greater than that of pure MOF-525 (37.2%) and ZnIn2S4 (70.0%), and it can still maintain good stability after five cycles reusing experiment. This work provides feasible insight for the preparation of novel and efficient PMOF-based photocatalysts in the future.
The complete chloroplast genome of Inula britannica and the phylogeny and evolution of the genus Inula
Authors: Yuan Lichai , Ni Yang , Li Jingling , Yang Heyu , Yue Jingwen , Zhang Xinyi , Chen Haimei , Liu Chang
Published: January 2023

Background Inula britannica
is an important medicinal plant of Asteraceae. Its dry capitulum has been used as a traditional Chinese herbal medicine, which had the functions of treating edemas, reduction in nausea, and preventing vomiting. There have not been many chloroplast genome studies.
Methods and results
we de novo assembly of the complete chloroplast genome of I. britannica. The genome was characterized and compared with the other five Inula species. The chloroplast genome of I. Britannica was 150,774 bp long. It showed a typical quadripartite structure, containing a large single-copy region, a small single-copy region, and a pair of inverted repeat regions, which were 82,451 bp, 18,423 bp, and 24,950 bp long, respectively. It encoded 109 unique genes, including 79 protein-coding genes, four rRNA genes, and 26 tRNA genes. Forty-nine long repetitive sequences and 69 simple sequence repeats were identified in the I. britannica chloroplast genome. We detected 14 hypervariable regions and identified six pairs of genus-specific DNA markers, which could differentiate congeneric species. Phylogenetic analysis showed that I. britannica was closely related to I. janopinca and I. linariifolia. Ancestral character state reconstruction indicated transitions from long spur to other petal types in Inula. Results from divergence time analysis showed that Inula diversified in the late Pliocene (~ 3.245 Mya).
Conclusion
In this study, we sequenced and assembled the chloroplast genome of I. Britannica. Phylogenomic analysis has identified species closely related to I. britannica, which will help determine its evolutionary relationships and taxonomic status.
Pollutant reduction analysis of a comprehensive utilization model of straw: A case study ofHenan, China
Authors: Gao Hengfei , Su Fangcheng , Zhang Yunpeng , Xu Qixiang
Published: January 2023

As a traditional agricultural country, China’s biomass energy sources account for a significant proportion of national energy consumption. Henan Province, a major agricultural province in China, produces a large amount of agroforestry biomass with the straw as the primary type every year. Due to the technological backward in rural areas, there are frequent agroforestry biomass direct burning activities (both open and residential), which not only wastes biomass resources but also produces large quantities of unorganized emissions of air pollutants that have adverse impacts on human health and air quality. In this study, the environmental impact of open burning of straw plus residential combustion of straw and firewood in Henan Province during the 2016 crop harvest period was investigated by emission inventories method and the numerical simulation by source-orientated air quality model system. The results showed that the monthly average of primary particulate matter emissions contribution from open burning of straw and residential combustion of straw and firewood in Henan province accounted for about 2.24% and 1.61% of the total amount of primary particulate matter generated by pollutant emission sources in Henan Province during the crop harvest period, respectively. A control scenario was designed based on national and local policies and regulations, in which straws used for cooking in rural areas were uniformly replaced by biogas, and straw burned in the open field in farmland was replaced in proportion to biomass briquette fuel. This control scenario leaded to significant reduction in emission intensities of SO2, PM2.5, PM10, CO, NO2 and VOCs throughout the year. Air quality results showed that in control scenarios, it was effective in reducing atmospheric particulate matter concentrations, while the impacts on SO2, CO, NO2, NH3, and O3 were negligible. The results of this study provided scientific guidance for the relevant biomass energy policy and related emission reduction strategies in Henan Province.
Binge-eating adolescent treatment (BEAT): Preliminary findings on efficacy and acceptance of a blended treatment program for youth with Loss of Control Eating: A within-subject waitlist control design.
Authors: Forrer Felicitas , Rubo Marius , Meyer Andrea H. , Munsch Simone
Published: January 2023

Background: Loss of Control Eating (LOC) is the most prevalent form of eating disorder pathology in youth, but research on evidence-based treatment in this group is scarce. We assessed for the first time the efficacy and acceptance of a blended treatment program for youth between 14 and 24 years with LOC (Binge-eating Adolescent Treatment, BEAT).
Methods: 24 youths (mean age 19.08 years) participated in three face-to-face workshops and six email-guided self-help sessions, followed by four e-mail guided follow up sessions, one, three, six and 12 months after the active treatment. All patients completed a two-weeks waiting-time period before treatment begin (within-subject waitlist control design).
Results: The number of weekly LOC episodes decreased during both the waiting-time and the active treatment period and remained more or less on the same level during the subsequent 12-months follow-up. Abstainer rates, depressive symptoms, eating disorder pathology and appearance-based rejection sensitivity all improved from pretreatment to posttreatment and typically further improved during follow-up. Body weight in contrast remained more or less constant within the same period. Treatment satisfaction among completers was high, but so was the dropout rate of 45.8% at the end of the 12 months follow-up.
Conclusions: This first blended treatment study BEAT might be well suited to decrease core symptoms of LOC, depressive symptoms and appearance-based rejection sensitivity. More research is needed to establish interventions targeted at reducing body weight change while at the same time holding dropout rates low.
Trial registration: The trial was registered at the German Clinical Trials Register (ID: DRKS00014580; registration date: 21/06/2018)
IonKit-NH: a MATLAB-based toolkit for ionospheric detection of natural hazard
Authors: Tang Long
Published: January 2023

In recent years, ionospheric sounding by GNSS total electron content (TEC) has been a powerful tool to detect the natural hazard such as earthquake, tsunami and volcanic eruption due to the fact that the natural hazard-produced acoustic waves or gravity waves can travel into the ionosphere and trigger travelling ionospheric disturbances (TIDs). However, open-source program on this field is scarce. Here, we developed a MATLAB-based toolkit, called IonKit-NH, to detection of natural hazard. IonKit-NH is capable of processing multi-system GNSS including GPS, GLONASS, Galileo and BDS and forming different dual-frequency combinations (such as L1 + L2 and L1 + L5 for GPS) to solve TEC. Based on the GNSS TEC, IonKit-NH generates the time-distance map and two-dimensional map of TEC variation, which can be used to obtain the characteristics of TIDs induced by natural hazard.
Evaluation of the recovery rate and prevention of hospitalization among covid-19 outpatients: a randomized clinical trial comparing N-acetylcysteine with Bromhexine
Authors: Ghayour Anahita Eslami , Nazari Sasan , Keramat Fariba , Shahbazi Fatemeh
Published: January 2023

Objectives: Due to the referral of COVID-19 patients to outpatient centers in the early stages, the aim of the present study is to compare the effect of N-acetylcysteine and Bromhexine on the recovery rate and prevention of hospitalization in outpatients with COVID-19
Methodology: This study was conducted from April 2022 to September 2022. First, PCR-confirmed COVID-19 patients were divided into two groups, one of these groups received N-acetylcysteine while the other received bromhexine. The patients were followed up on the seventh and fourteenth days of the disease in terms of the duration of changes in oxygen saturation and recovery. The hospitalization and death of the patients were also evaluated after one month.
Results: Out of 150 studied patients, oxygen saturation was increased by 1.33% in the third visit of the patients who received N-acetylcysteine compared to their first visit. This percentage was 1.19% in the patients who received bromhexine.11.33% of the patients were admitted to the hospital and 88.6% of them had no history of hospitalization within 14 day and their mortality rate was zero.
Conclusions: The results of this study showed that early initiation of Bromhexine can effectively reduce the hospitalization rate and shorten the duration of hospitalization.
Clinical trial code: IRCT20220302054167N1 and ethics code: IR.UMSHA.REC.1400.957
Unusual softening-to-hardening switching in branched carbon nanotube nanocomposites
Authors: Lacarbonara Walter , Guruva Sawan Kumar , Carboni Biagio , Krause Beate , Janke Andreas , Formica Giovanni , Lanzara Giulia
Published: January 2023

The unusual features of the nonlinear dynamic response of nanocomposite beams made of polybutylene terephthalate (PBT) and branched carbon nanotubes (bCNTs) are documented experimentally. The frequency response curves for cantilever specimens with different bCNTs weight fractions (wt%) are obtained under harmonic base excitations by measuring the free tip displacement via 3D scanning laser vibrometry. The steady-state response acquired for different excitation levels exhibits a surprising nonlinear softening trend which is switched into hardening for higher bCNTs wt% and increasing oscillation amplitudes. The stick-slip hysteresis, caused by the interaction of the bCNTs with the thermoplastic hosting matrix, determines a softening nonlinearity of the material that counteracts the well-known geometric hardening associated with the nonlinear curvature of the first mode of the cantilever. However, for bCNTs weight fractions greater than 1%, the bridging of the branched CNTs gives rise to the formation of a strong network which contributes to the hardening response at higher oscillation amplitudes. This mechanical behavior is detected by the trend of the nonlinear harmonic spectra and by the estimation of the equivalent damping ratio using the half power bandwidth method. A nonlinear mathematical model of the nanocomposite cantilever samples derived from a 3D mesoscale hysteretic model of the PBT/bCNT material is shown to predict the observed unusual experimental behavior. The presence of bCNTs in a thermoplastic matrix seems to be the main driver of the highly tunable nonlinear stiffness and damping capacity.
The global scenario of hydrogeochemical research on glacier meltwater: A bibliometric and visualization analysis
Authors: Kumar Ramesh , Pippal Prity Singh , Kumar Rajesh , Kumar Pankaj , Singh Atar , Sharma Payal
Published: January 2023

Hydro-geochemistry plays a vital role in sustainable development, but only a few reviews have documented the development in this field. It is a bibliometric visualization based on the Web of Science database through Biblioshiny and VOSviewer to analyze the current status of hydrogeochemical research from 2002–2022. In recent years, there has been a significant increase in scientific studies investigating the hydrogeochemical characterization of glacier meltwater. The Web of Science Core Collection (WoSCC) database helped to retrieve the research papers published in conjunction with hydrogeochemical investigations of glacier meltwater between 2002 and 2022. From the beginning of 2002 till July 2022, a total of 6035 publications on the hydrogeochemical study of glacier meltwater were compiled. The number of publications produced from the United States of America (USA) and China accounts for about half (50%) of all publications from the top 10 countries. The findings of this study demonstrated that there had been an increase in research into hydrogeochemistry at higher altitudes, but the results have not shown any significant differences. However, developed nations, particularly the United States, emphasize hydrogeochemical research more than developing nations. However, there is not a single nation that consistently advances research in hydrogeochemistry at high elevations. Because of this, additional research might be conducted worldwide utilizing innovative techniques and resources in this research domain. In addition, our understanding of glacier meltwater's role in streamflow components is limited and needs to be expanded through further research in the future.
Experimental study of microwave-catalytic oxidative degradation of COD in livestock farming effluent by copper-loaded activated carbon
Authors: Cai Qingfeng , zhang xiao , geng wenguang , liu fang , yuan dongling , sun rongfeng
Published: January 2023

CuO/granular activated carbon (GAC) catalysts were prepared in this work and used as heterogeneous catalysts for the degradation of chemical oxygen demand (COD) in the microwave (MW)-induced H2O2catalytic oxidation process. The prepared catalysts were characterized by scanning electron microscopy (SEM), energy dispersive X-ray spectrometry (EDS), X-ray diffraction (XRD), and N2adsorption-desorption techniques. The results showed that CuO was loaded on the GAC surface. Subsequently, the effects of catalyst dosage, H2O2dosage, pH, MW power, and MW irradiation time on the degradation efficiency were studied. The orthogonal experiment showed that the initial PH value had the greatest effect on COD removal rate in the microwave-assisted reaction system with CuO/GAC as catalyst.The COD was degraded quickly and efficiently by the combined method of MW/catalyst/H2O2, and the mechanism of microwave catalytic oxidation and H2O2degradation of farm wastewater COD was discussed.
Cities and epidemics: Reflection based on spatio-temporal spread and medical carrying capacity of early COVID-19 outbreak in China
Authors: Lan Li , Li Gang , Mehmood Muhammad Sajid , Xu Tingting , Wang Wei , Nie Qifan
Published: January 2023

New and more dreadful viruses may emerge again in the future and cause a large demand for medical care. It is essential to explore different cities’ early spatio-temporal spread characteristics of the COVID-19 epidemic and the medical carrying capacity. This study examined the situation of six high-incidence Chinese cities using an integrated manual text and spatial analysis approach. Results show that the initial COVID-19 outbreak went through three phases: unknown-origin incubation, Wuhan-related outbreak, and local exposure outbreak. Cities with massive confirmed cases exhibited the multicore pattern, while those with fewer cases exhibited the single-core pattern. The cores were hierarchically located in the central built-up areas of cities’ economic, political, or transportation centers, and the radii of the cores shrank as the central built-up area’s level decreased, showing the hierarchical decay and the core-edge structure. That is, a decentralized built environment (non-clustered economies and populations) is less likely to create a large-scale epidemic cluster. Besides, the clusters of excellent hospital resources were consistent with those of COVID-19 outbreaks, but their carrying capacity still needs urgent improvement. And the essence of prevention and control is the governance of human activities and the management, allocation, and efficient use of limited resources about people, places, and materials leveraging IT and GIS, to confront the contradiction between supply and demand.
Patients with rheumatic immune diseases on immunosuppressants who died of Nocardia farcinica infection - case report
Authors: Han Yu-Yan , Huang Lu-Lu , Yang Meng-Ni , Huang Zong-Shuai , Huang Shi-Hong , Xie Yang , Huang Yan , Xiao Yuan-Yuan , Chen Hua , You Yun-Hui
Published: January 2023

Background: Nocardiosis is a rare suppurative infectious disease caused by Nocardia, a gram-positive filamentous bacterium that is widely distributed in air, water, soil and other media. It usually occurs in patients treated with immunosuppressants but can also occur in healthy people. The aim of this study was to describe the course of two patients with rheumatic immune diseases who died of pneumonia and brain, renal, liver abscesses and sepsis caused by Nocardia farcinica infection.
Case presentation: A 74-year-old retired male, diagnosed with dermatomyositis (DM), and a 54-year-old female farmer, diagnosed with systemic lupus erythematosus (SLE), both taking glucocorticoids and immunosuppressants, suffered from pneumonia and brain, renal, and liver abscesses and sepsis caused by Nocardia farcinica. Their medical treatment processes were very complicated, and they underwent multiple examinations and multidisciplinary consultations. They were finally diagnosed with pneumonia, brain, renal, and liver abscesses and sepsis caused by Nocardia farcinica infection through blood, sputum and bronchoalveolar lavage fluid culture. They were treated with antibacterial drugs, but the course was insufficient because of economic reasons, and eventually, they died.
Conclusions: Nocardia farcinica is a rare but possible cause of pneumonia or brain, renal, liver abscesses or sepsis inpatients with rheumatic immune diseases. If infection is not ruled out in the lungs or other organs, it is necessary to actively utilise a variety of pathogenic tests, including blood culture. Once patients with immunosuppressive agents get pneumonia, brain abscesses, renal abscesses, liver abscesses or sepsis caused by Nocardia farcinica, they are in a critical condition and easily die.
Insight into the differences in carbon dots prepared from fish scales using conventional hydrothermal and microwave methods
Authors: Xu Chengzhi , Xiao Xiao , Cai Chaonan , Cheng Qunpeng , Zhu Lian , Zhang Juntao , Wei Benmei , Wang Haibo
Published: January 2023

The preparation of carbon dots (CDs) from waste fish scales is an attractive and high-value transformation. In this study, fish scales were used as a precursor to prepare CDs, and the effects of hydrothermal and microwave methods on their fluorescence properties and structures were evaluated. The microwave method was more conducive to the self-doping of nitrogen due to rapid and uniform heating. However, the low temperature associated with the microwave method resulted in the insufficient dissolution of the organic matter in fish scales; thus, the organic matter was difficult to completely dehydrate and condense, but formed nanosheet-like CDs, whose emission behavior had no significant correlation with excitation. Although the CDs prepared using the conventional hydrothermal had a lower doping amount of N element, the relative pyrrolic N content was higher, which was beneficial in improving their quantum yield. Additionally, the controllable high temperature and sealed environment used for the conventional hydrothermal could promote the dehydration and condensation of the organic matter in fish scales to form CDs with a higher degree of carbonization, uniform size, and higher C = O/COOH content. CDs prepared using the conventional hydrothermal exhibited higher quantum yield and excitation wavelength-dependent emission behavior.