bluuebunny/crossref_metadata_2025 huggingface dataset:
Outcome of Obstructed Total Anamalous Pulmonary Venous Connection (TAPVC) Repair Patients with Milrinone Versus Milrinone and Inhaled Nitric Oxide (INO): A Prospective Randomized Observational Study
Authors: Gujja Srikanth , Prajapati Mrugesh , Chuada Tanya R , Gandhi Hemang , Arora Varun , Kaul Vivek , Patel Sanjay
Published: June 2023

Background:

Obstructed total anomalous pulmonary venous connection (TAPVC) typically present with severe cardiovascular decompensation and requires urgent surgical management. Pulmonary arterial hypertension (PAH) is a major risk factor affecting mortality. Perioperative management focuses on providing inotropic support and managing potential pulmonary hypertensive episodes. Milrinone and inhaled nitric oxide (iNO) efficiently reduce pulmonary artery pressure (PAP) and help to improve the outcome. The aim was to determine the outcome of patients with high PAP with milrinone alone and a combination of iNO and milrinone.

Material and Method:

After ethical committee approval, the study was conducted over a period of 3 years in 80 patients with obstructed TAPVC repair. A total of 80 patients having severe PAH (supra systemic arterial pressure) randomly divided into two groups with 40 patients in each (M & MN). Group M (milrinone) patients received milrinone and Group MN (milrinone & iNO) patients received both milrinone (after opening aortic cross clamp) and iNO (post operative ICU). Ventilation time, hospital stay, ICU stay, complications, in hospital mortality were compared between both groups.

Result:

Ventilation time, Intensive Care Unit (ICU) stay, hospital stay for group M was 8.02 ± 5.74 days, 11.25 ± 7.33 day, 14.92 ± 8.55 days, respectively, and for group MN was 5.02 ± 1.78 days, 8.27 ± 3.24 days, 10.3 ± 3.18 days, respectively. In hospital mortality for group M and MN was 10% and 2.5%, respectively. P value for each variable was significant < 0.05 (except mortality).

Conclusion:

Most of the patients with obstructed TAPVC had severe PAH. Management of severe PAH with a combination of milrinone with iNO had a better outcome than milrinone alone.
Bibliometric Analysis of the Worldwide Scientific Production on COVID-19 Infection and Cerebrovascular Disease
Authors: Palomino-Leyva Camila , Rivera-Recuenco Jhonny , Fernandez-Giusti Alicia , Barja-Ore John , Retamozo-Siancas Yesenia , Mayta-Tovalino Frank
Published: June 2023

Objective:

To identify the worldwide bibliometric characteristics of research on SARS-CoV-2 infection and cerebrovascular disease.

Methods:

A retrospective, descriptive, and bibliometric study was performed. We analyzed 1834 publications about COVID-19 and cerebrovascular disease from the Scopus database considering the time since the beginning of the pandemic between 2019 and 2020. Bibliometric indicators were evaluated such as number of citations, citations per publication by authors, countries, journals, and collaborations at national, international, institutional, and impact levels according to Cite Score Quartile and h-index metrics. All analysis was performed using SciVal software.

Results:

The highest percentage of articles corresponded to universities in the United States, including Harvard and New York with 59 and 20 publications, respectively, and the University of Toronto in Canada with 22 publications. In relation to citation indicators, journals such as Stroke and Journal Stroke and Cerebrovascular diseases obtained 1971 and 561 citations, respectively. Regarding collaboration indicators, the national collaboration index was 39.4% and the institutional collaboration index was 31.1%. Finally, neurology, cardiovascular medicine, and cardiology and surgery were the subject areas with the highest research results, with 424, 217, and 128 studies, respectively.

Conclusion:

It was observed that the United States was the country with the highest scientific production on COVID-19 and cerebrovascular disease in the year 2020 in the different health areas; however, more research is still needed worldwide for a better analysis of the bibliometric indicators on the subject.
Hemophagocytic Lymphohistiocytosis: A Study of 14 Cases
Authors: Harrison Aradhana , Rao Namrata , Hebbar Ankitha , Pavithra P.
Published: June 2023

Context:

Hemophagocytic lymphohistiocytosis (HLH) is a hyperactive, but ineffective immune response releasing proinflammatory cytokines, culminating in multiorgan failure and death. Clinical mimickers, lack of gold standard tests, equivocal diagnostic criteria, and limited literature delay the diagnosis. After a comprehensive literature review, we surmise that this is the largest study in India involving 14 patients.

Settings and Design:

This was a retrospective observational study.

Subjects and Methods:

Out of 11,272 bone marrow (BM) examinations in 5 years and 3 months, hemophagocytosis was observed in 133 aspirates. Clinical details of these were reviewed.

Results:

Fourteen patients fulfilling HLH-2004 criteria were included in the study. Infection associated HLH was seen in 71.4% patients. Malignancy and autoimmune disease were seen in 14.2% patients each. Fever was the most common presentation. Splenomegaly was seen in only 21.4% cases. Cytopaenia was present in all patients. Hypertriglyceridaemia was seen in 85.7% patients. Hyperferritinaemia was seen in 92.8% patients. Hemophagocytosis was seen in all patients.

Conclusions:

HLH should be suspected in cases with cytopaenia and hyperinflammatory markers. Early BM examination, clubbed with appropriate investigations, points to the diagnosis. Newer diagnostic modalities are available however, not much is known about their efficacy. More research in this field will immensely contribute to timely initiation of therapy and improved outcome of HLH.
Preoperative T Staging of Gastrointestinal Malignancy By MDCT– An Essential Tool for Surgical Management
Authors: Unadkat Bhavik Sunit , Kashikar Shivali Vaibhav , Mishra Gaurav Vedprakash , Parihar Pratapsingh H , Shetty Neha Dinesh , Bhansali Pratik Jayprakash , Gowda K. B. Harshith
Published: June 2023

Background:

Malignancy with respect to the stomach and small and large intestines can present as a mass or focal/diffuse bowel wall thickening, with associated perienteric abnormalities. The role of multidetector computed tomography (MDCT) in gastrointestinal malignancy is pivotal, as it provides high-resolution images for accurate preoperative staging of gastrointestinal tumors and can help in the surgical management of patients.

Aim and Objectives:

The goal of this study was to evaluate the role of MDCT in the evaluation of gastrointestinal malignancy, to differentiate between benign and malignant gastrointestinal disorders, and to stage a malignant lesion preoperatively.

Materials and Methods:

This study was conducted at the Radiodiagnosis Department of AVBRH, a teaching hospital of DMIHER, Sawangi (Meghe), Wardha. It was a prospective cross-sectional study. A purposive convenience sampling method with a desired sample size of 50 participants for the study was conducted over a duration of 2 years.

Results:

Our study included 51 subjects, of which the majority, 32 (62.75%), were male, and the rest, 19 (37.25%), were female. Among the study population, 46 (90.2%) were malignant lesions, and the rest, 5 (9.8%), were benign, according to the MDCT diagnosis. The majority, i.e. 32 (62.75%) individuals, had colorectal cancer. The majority of individuals with malignancy, i.e. 46 (90.2%), had a heterogeneous pattern of gastrointestinal wall enhancement along with asymmetric wall thickening in 44 (86.27%) individuals. Segmental gastrointestinal wall involvement was seen in 35 (68.63%) individuals.

Conclusion:

MDCT can accurately differentiate benign and malignant diseases based on the pattern of wall thickening and offers information on any accompanying pericolic abnormalities, the existence of nodal or distant metastases, and the invasion of nearby organs. The accurate planning of surgery and patient care is made possible by the preoperative staging of malignant lesions by MDCT.
Sputum Culture Conversion among Patients with Drug-Resistant Tuberculosis: A Study of Various Predictors
Authors: Khan Shafee , Choudhary Sumer , Aurangabadkar Gaurang , Bankar Nandkishor
Published: June 2023

Introduction:

Conversion of a positive sputum culture to a negative culture is an important parameter in the management of drug-resistant tuberculosis (TB), as the failure to convert was related to dismal posttreatment outcomes and elevated mortality rates by almost eight times when compared to victims of multidrug-resistant TB (MDR-TB) who did so. In the patients of MDR-TB, it is an important sign of treatment success to have sputum culture converted from positive to negative, and helps in determining the duration of treatment. The goal of this study was to examine and compare the length of time it took to convert an initial sputum culture with predictors of treatment outcomes for patients with MDR-TB, as well as to pinpoint the variables that affected the length of time.

Materials and Methods:

The mixed method (records review and qualitative approach) was used to understand the patient’s perspective for accepting the Programmatic Management of Drug-resistant TB (PMDT) services and the provider’s perspective for rendering services in a public-private mix model setup. This study was undertaken as a retrospective analysis and studied the patients drug-resistant TB who were admitted to a tertiary care hospital in central India. This study was carried out on the patients of Rifampicin-Resistant TB (RR-TB) and MDR-TB (Resistant to both INH and Rifampicin) with positive baseline culture, pretreatment evaluation, and appropriate anti-MDR-TB treatment. As per the PMDT guidelines, sputum smear and culture reports were collected and analyzed.

Results:

In this study, the time and predictors to convert an initial positive sputum culture to negative and factors influencing treatment outcome were evaluated, compared, and identified. A total of 163 patients were evaluated and analyzed. Of these, 111 (68.09%) were rifampicin and INH-resistant (MDR-TB), whereas 52 (31.90%) were rifampicin resistant (RR-TB) only. Overall 68 (41.71%) patients with baseline positive culture were converted within 3 months.

Conclusions:

It was concluded that malnourishment, human immunodeficiency virus positivity, associated extra pulmonary TB, and bilateral cavitation were found to be significant predictors of longer time of sputum culture conversion and thereby treatment outcome.
Role of Strain Elastography in the Diagnosis of Superficial Soft-Tissue Lesions
Authors: Gowda K. B. Harshith , Mishra Gaurav Vedprakash , Parihar Pratapsingh H , Dhande Rajasbala Pradeep , Luharia Anurag
Published: June 2023

Background:

Elastography, recent progress in the field of imaging, is an innovative approach which provides information pertaining to tissue elasticity. Charting the stiffness can be performed either by assessing the same, using the evaluation of the strain i n the mass of cells in the presence of stress or assessment of shear waves, the propagation of which is dependent on the tissue stiffness, using imaging tools. This study was done to investigate the validity of strain elastography in the diagnosis of superficial soft-tissue lesions in contrast to histopathological examination (HPE) due to the dearth of studies comparing strain elastography and HPE, particularly in the Indian context.

Materials and Methods:

The present longitudinal study was conducted by the Department of Radiology at AVBRH, Sawangi, Wardha, from the year 2020 to 2022. Ninety-six subjects who were diagnosed or clinically suspected superficial soft-tissue lesions irrespective of age and gender were included. All patients underwent ultrasound, elastography, and final diagnosis was confirmed with HPE. Institutional Ethical Clearance (No: DMIMS [DU]/IEC/2022/340) and before the initiation of the investigation and the recruitment of patients into the study, informed consent was obtained. Chi-square test, Mann–Whitney U-test, and Kruskal–Wallis test were the tests of significance.

Results:

The subjects’ average age was 40.38 ± 18.95 years, and 57.3% of them were women. On HPE, 21 lesions (21.8%) were categorized as malignant and 75 lesions (77.2%) as benign. The mean strain ratio (SR) was 11.7 ± 4.8 for malignant lesions and 2.5 ± 4.6 for benign lesions. Malignant and benign lesions had a noticeable change in SR. To distinguish between malignant and benign soft-tissue lesions, an SR of >3 had a sensitivity of 95.24%, specificity of 91.89%, positive predictive value of 87.0%, and negative predictive value of 97.1%.

Conclusion:

SR of malignant lesions was higher than that of benign soft-tissue lesions. SRs performed better as a diagnostic tool than elasticity scores hence, SRs can be utilized as a marker to foretell a soft-tissue tumor’s propensity for malignancy.
Efficacy of Closed and Open Endotracheal Suction on Prevention of Ventilator-Associated Pneumonia on Patients Admitted to Critical Care Unit at Tertiary Care Hospital
Authors: Mulla Ruksar Jainuddin , Mohite Vaishali Rajsinh
Published: June 2023

Background:

Endotracheal suctioning is a method commonly used to clean airway secretions in patients under mechanical ventilation. This study aimed to compare the effects of open and closed suction methods on the occurrence of ventilator-associated pneumonia (VAP). In the open endotracheal suction, the approach necessitates the participation of two nurses and may result in a momentary interruption of ventilation and oxygen supply due to the patient’s disconnection from the ventilation device during suctioning. In the closed endotracheal suction, the approach can be performed through connections in a closed suction set while the patient is ventilated without separating the patient from the ventilator.

Objective:

(1). To compare the close endotracheal suction with open endotracheal suction for the prevention of VAP. (2) To assess the incidence of VAP among intubated patients.

Materials and Methods:

The study was conducted among 60 patients who are on mechanical ventilator in the critical care unit in tertiary care hospital. For the study, simple random sampling technique is used for the selection of sample. Using a lottery method of sampling, one in the experimental group and one in the control group on the basis of inclusion criteria.

Results:

The study was done on patients who are on mechanical ventilators in the critical care unit in tertiary care hospitals. The data analysis was done using descriptive and inferential statistics. The study finding revealed that in VAP scoring of the patient’s 1st and 2nd day in open endotracheal suction, there are no significant changes in open endotracheal suction then null hypothesis was accepted (t = 0.9, P = 0.37). VAP scoring of the patient’s 2nd and 3rd day and 3rd and 1st day in open endotracheal suction, there are significant changes in open endotracheal suction method in null hypothesis was rejected (P < 0.05). VAP scoring of the patient’s 1st and 2nd day and 2nd and 3rd day and 3rd and 1st day in closed endotracheal suction, there are significant changes in closed endotracheal suction then null hypothesis was rejected (P < 0.05).

Conclusion:

The study assessed the efficacy of open endotracheal suction versus closed endotracheal suction on age, sex, duration of hospital stays, return of mechanical ventilation, and mode of ventilation are not significant but the duration of mechanical ventilation is significant. The nurses play a vital role in assessing the cardiac monitor while doing suctioning to prevent cardiorespiratory complications.
Methemoglobin and Inflammatory Markers in the Context of Mortality in COVID-19 Disease
Authors: Pawar Vaishali Satyajeet , Sontakke Ajit V. , Pawar Satyajeet K.
Published: June 2023

Context:

Today, the world is in search of potential biomarkers for assessing the severity and prognosis of coronavirus disease-2019 (COVID-19) disease with its different clinical presentations.

Aim:

The aim of this study was to assess the roles of C-reactive protein (CRP), lactate dehydrogenase (LDH), procalcitonin (PCT), and methemoglobin (Met-Hb) in the clinical outcome of COVID-19 patients.

Settings and Design:

This observational cross-sectional study was conducted in COVID-19 cases admitted in the intensive care unit (ICU) of a tertiary care hospital from June 2021 to October 2021.

Subjects and Methods:

For all selected patients, estimation of CRP, LDH, PCT, and Met-Hb levels was done on the 2nd–3rd days of hospital admission, and definitive outcomes were included sequentially.

Results:

Out of 495 ICU admissions, 69 patients were evaluated in the end. Out of which, 27 patients died during the hospital stay. The mean Met-Hb, LDH, PCT, and CRP levels in nonsurvivors were significantly high. In multivariate bivariate regression analysis, age (odds ratio [OR]–1.06; 95% confidence interval [CI]: 1.01–1.13; P = 0.021), LDH (OR–1.006; 95% CI: 1.001–1.010; P = 0.013), and CRP (OR–1.03; 95% CI: 1.002–1.6; P = 0.047) were independently associated with nonsurvival of the patients. The receiver operating characteristic curve showed a cutoff value of 684 U/L for LDH which predicted mortality due to COVID-19 disease with 66.7% sensitivity and 70.4% specificity. For CRP, a cutoff value of 28.3 mg/L predicted mortality with 73.8% sensitivity and 59.3% specificity.

Conclusions:

In conclusion, higher levels of LDH and CRP were related to mortality due to COVID-19 disease. Slightly raised values of Met-Hb in nonsurvivors suggest nonresponding hypoxia. The research in this context may open new options in the treatment of COVID-19 disease.
Characteristics and Outcomes of Adolescents Requiring Admission to the Intensive Care Unit
Authors: Al-Dorzi Hasan M. , Yaqoub Amirah S. , Aldokhel Fisal T. , Alshuwaier Khalid M. , Almujarri Sarah F. , Alkhaldi Fatima A.
Published: June 2023

Background:

Critically ill adolescents are not a well-studied patient population. The optimal setting (pediatric or adult intensive care unit [ICU]) for caring for them is not clear. This study assessed adolescents admitted to the adult ICU and compared the characteristics and outcomes of younger versus older patients.

Methods:

This was a retrospective study of adolescent patients aged 14–19 years who were admitted to an adult tertiary care ICU between January 1, 2015, and December 31, 2020. Patients were divided into two groups, younger (14–16 years old) and older adolescents (17–19 years old).

Results:

The study included 276 patients; 105 patients were aged 14–16 years and 171 patients 17–19 years. Most patients were males (69.9%); only nine patients had body weights < 30 kg. Trauma was the most common reason for admission (36.2% of the younger group and 49.7% of the older group, P = 0.03) with sepsis being also common (19% of the younger group and 20.5% of the older group). Vasopressor therapy was required for 39.1% of patients and invasive mechanical ventilation for 58% (no between-group difference). The hospital mortality was 16.7% (odds ratio in younger versus older group adjusted for illness severity, 0.804; 95% confidence interval, 0.358–1.802). Mechanical ventilation duration and stay in the ICU and hospital were similar in both groups.

Conclusions:

Trauma was the most common reason for admission of adolescents aged 14–19 years to the adult ICU. The hospital mortality of younger and older adolescents was similar, suggesting that the management of younger adolescents in the adult ICU is safe.
Quantifying Social Value Information Using Analytical Hierarchy Process Method
Authors: Choi Young-Chool , Kang Ji-Youn , Kim Hong-Sam , Cho Kyung-Soon , Lee Eun-Hee
Published: June 2023

This study aims to develop a methodology that can quantify social value at the practical level, considering that it is difficult to quantify the social value information of individual businesses despite the importance of social value both in practice and academia. As people’s living standards rise, the gap between rich and poor has widened, and this phenomenon is broadening the scope of the social welfare projects that central and local governments must carry out. In this context, quantifying the social value information that each project will have is extremely important. However, the reality is that the social value quantification work undertaken in academia has up until now been carried out on an abstract level, because the methodology has not been established. In addition, established social value quantification methodologies embody a problem: it is difficult for policymakers to utilize them, because they represent difficult processes that, in respect of each individual project, require large amounts of professional knowledge, data, time and money if they are to be carried out satisfactorily. Against this background, this study aims to present a single social value quantification methodology that policymakers can employ easily in all circumstances. If the social value quantification method presented in this study, the Analytical Hierarchy Process (AHP) method, is properly applied, then, since it is information and data -based methodology, it should prove meaningful as a practical alternative to existing methods.
Brake Insulator Damping Measurement Procedure
Authors:   Brake NVH Standards Committee
Published: June 2023

This procedure is applicable to modes from 500 and 13,000 Hz. The parameters measured with this procedure are defined as the damping factor, ξ for first nine vibration modes of the beam. The measurement will be done in free-free conditions and with temperature.
Marketing Mix In Influence The Decisions Of Muslim Consumer Using Online Food Delivery Services
Authors: Jannah Nurotun , Nasrulloh Nasrulloh
Published: June 2023

This research aims to analyze and show the effect of product, price, promotion, distribution, people, process, and physical evidence on Muslim consumers' decisions to use ShopeeFood services. This study uses a descriptive quantitative approach. Muslim ShopeeFood users in Gresik Regency are the population of this study, where the number is unknown. The sampling technique used random sampling by measuring the number of samples using the unknown population approach to obtain a total sample of 100 respondents. The research uses primary data in the form of questionnaires and secondary data in the form of literature. Data were analyzed using multiple linear regression, but first tested the validity, reliability, and classical assumptions. The results of this study indicate that product, price, promotion, distribution, process, and physical evidence positively and significantly influence Muslim consumers' decisions to use ShopeeFood services. Meanwhile, the person variable does not influence the Muslim consumer's decision to use ShopeeFood services. The decision of Muslim consumers to use ShoeeFood's services is significantly influenced by product, price, promotion, distribution, people, process, and physical evidence factors. This research can be used as a reference for online food delivery service providers, especially ShopeeFood, in marketing management to increase sales transactions, especially in Gresik Regency.
Analysis of Consumption Expenditure of Tourists Visiting Korea by Differences in National Culture: Focusing on Southeast Asian Countries
Authors:   The Korean-Japanese Economics & Management Association, Kim Do-Hoon
Published: June 2023

Purpose: The purpose of this study is to compare and analyze the tourism behavioral characteristics, spending patterns, and determinants of consumption expenditure for Southeast Asian tourists visiting Korea based on national cultural differences. The research methods to achieve the objectives of this study are as follows: First, using Hofstede’s six cultural dimensions scores for Korea and major Southeast Asian countries, the KSI index will be calculated to measure the cultural distance between them. Based on the KSI index, the two countries with the closest and farthest cultural distances will be selected as the target countries for the study. Secondly, a comparative analysis will be conducted on the tourism behavioral characteristics, spending patterns, and determinants of consumption expenditure for tourists from the two selected countries visiting Korea.
Research design, data, and methodology: The data for the study sample was obtained from the original 2019 survey data on inbound tourists provided by the Korea Tourism Data Lab (2023). and Data from a sample of 522 Indonesian and 622 Filipino tourists who visited Korea were used for the analysis. First, we conducted frequency analysis to examine demographic characteristics, tourism behavior, and spending patterns. and the estimation analysis method used to identify the determinants of tourist consumption expenditure is Tobit model analysis method.
Results: This research results are as follows. First, It was found that there are differences in expenditure characteristics and determinants of consumption expenditure between Indonesian and Filipino tourists visiting Korea. Second, according to the estimation results, In the case of Indonesian tourists, it was estimated that individual travel and travel satisfaction have a positive impact on consumption expenditure. and it was found that Filipino tourists spend more on group tours than on individual tours. Third, both countries showed that the proportion of cultural and entertainment expenses was the lowest among the consumption expenditure items.
Implications: The results of this study showed that there were differences in the consumption characteristics of tourists and the determinants of tourism expenditure depending on the cultural differences between the two countries. the tourism marketing strategy and policy development should reflect the cultural characteristics of the country visited, and it is necessary to consider the national cultural dimensions in formulating strategies.
Practical Related-Key Forgery Attacks on Full-Round TinyJAMBU-192/256
Authors: Dunkelman Orr , Ghosh Shibam , Lambooij Eran
Published: June 2023

TinyJAMBU is one of the finalists in the NIST lightweight cryptography competition. It is considered to be one of the more efficient ciphers in the competition and has undergone extensive analysis in recent years as both the keyed permutation as well as the mode are new designs. In this paper we present a related-key forgery attack on the updated TinyJAMBU-v2 scheme with 256- and 192-bit keys. We introduce a high probability related-key differential attack where the differences are only introduced into the key state. Therefore, the characteristic is applicable to the TinyJAMBU mode and can be used to mount a forgery attack. The time and data complexity of the forgery are 233 using 214 related-keys for the 256-bit key version, and 243 using 216 related-keys for the 192-bit key version.For the 128-bit key we construct a related-key differential characteristic on the full keyed permutation of TinyJAMBU with a probability of 2−16. We extend the relatedkey differential characteristics on TinyJAMBU to practical-time key-recovery attacks that extract the full key from the keyed permutation with a time and data complexity of 224, 221, and 219 for respectively the 128-, 192-, and 256-bit key variants.All characteristics are experimentally verified and we provide key nonce pairs that produce the same tag to show the feasibility of the forgery attack. We note that the designers do not claim related-key security, however, the attacks proposed in this paper suggest that the scheme is not key-commiting, which has been recently identified as a favorable property for AEAD schemes.
Case Study on the Construction of Main Tunnel and Parallel Safety Tunnel From Tupul to Imphal Railway Line under Northeast Frontier Railway, Manipur.
Authors: Elizabeth Khaidem  , M Dhaarani
Published: June 2023

As India’s Northeast region comes under the 6th most earthquake- prone belt in the world, the soil of young Himalayan region is weak due to the heavy monsoon for a longer period and working season is very less in the hilly region. The capital of Manipur, Imphal is the fourth capital city in the mountainous North-Eastern region to be connected with railways after three other Northeast states. The soil or the earth bearing capacity of the North Eastern region is much less as to compared other parts of the country. It had caused many problems that led to the deformations of the soil around the primary supports of the faces of the Tunnel-12 especially. Thus, geoconsultants and expert committees consisting of the various international consultants are also studying and giving guidance on the deformations formed on the strata of the earth.
Screening and production of bacterial amylase from different Strepomyces species
Authors: Dr. Rachana Choudhary  , Dr. Bhuneshwari Nayak
Published: June 2023

The enzymes from the microbial sources are more stable and can be obtained from cheap sources. Amylase is most important industrial enzyme which is widely used in food and biofuel industries. Streptomyces is a group of bacteria belongs to largest genus of Actinobacteria and commonly isolated from the soil. Streptomyces species have been widely used as microbial cell in industries for production of antibiotics. For the production of antibiotics, Streptomyces species are frequently used as microbial cells. This study reported that screening and production of amylase from different Streptomyces species i.e. Streptomyces microflavus, Streptomyces cyaneus and Streptomyces diastaticus. The cultures were screened for the production of amylase by starch agar plate assay. Result shown the Streptomyces diastaticus was better amylase enzyme producer compare to Streptomyces microflavus and Streptomyces cyaneus. Streptomyces diastaticus gives maximum starch hydrolysis by showing clear zone (4.4 mm), enzyme production (1.60 U/ml) and protein concentration (2.25 mg/ml).
Evaluación del procedimiento operativo en un centro de emprendimiento público del Cantón Quevedo, Ecuador
Authors: Carpio Byron Andres Burgos , Rivas Carmen Alexandra Sinchi , Cañarte Carlos Alberto Nieto , Moran Evelyn Gabriela Perez
Published: June 2023

​La presente investigación se realizó con el fin de conocer la gestión operativa y su incidencia en la zona norte del centro de emprendimiento de la prefectura de Los Ríos en el cantón Quevedo. El objetivo general es “Analizar la gestión Operativa en el centro de emprendimiento de la zona norte de la prefectura de Los Ríos en el cantón Quevedo, año 2021”. La investigación tiene un enfoque mixto, se centrará en realizar un análisis de datos mediante entrevistas y encuestas para determinar la situación sobre gestión operativa del centro, se aplicará una matriz de Vester y metodología de marco lógico para presentar una propuesta de mejora. La muestra estuvo constituida por 15 colaboradores y 100 emprendedores asociados al centro. Los resultados permitieron conocer que dentro centro de emprendimiento existen debilidades como su planificación presupuestaria generalizada donde no se detalla valores asignados para cada rubro; sus colaboradores consideran que la gestión operativa es excelente en un 60%, siendo un aspecto negativo que solo reciben capacitaciones dos veces por año, y también que un 40% de las actividades destinadas en atención al usuario solo se planifican de forma ocasional; la propuesta se realizó a empleado un matriz de Vester para identificar el problema crítico central, y a partir de ello se aplicó la matriz de marco lógico cuyo fin es mejorar el aprovechamiento y distribución de recursos tiempo e insumos para beneficio de los usuarios del centro.
ANALYSIS OF THE NUMBER OF RAPE CASES IN A MUNICIPALITY IN NORTH FLUMINENSE
Authors: Antunes Merat Danillo , Longue Correa Leticia , Oliveira de Carvalho Hentzy Rober Mathan , Cabreira da Silva Thaynara , dos Santos Dias Cola Claudio
Published: June 2023

Introduction: Rape means any oppression to the free exercise of an individual’s sexuality, whether for the purpose of reproduction or the pursuit of pleasure. Objective: Analyzing the cases of rape in Campos dos Goytacazes/RJ, computing its incidence, percentage in different perspectives and identifying the prevalence. Material and methods: Conducted through an exploratory and descriptive research, with a survey of data available at the Institute of Public Security of the State of Rio de Janeiro, being computed the data referring to Campos dos Goytacazes, North Fluminense Region and State of Rio de Janeiro, for comparison of information, between January and September of the years 2019 and 2020. Results: There was a drop in rape reports between the years analyzed. Within this perspective, it is questioned whether there was a reduction in cases or notifications. Regarding victims, there is a prevalence of women in relation to men, with a preponderance of white victims, followed by brown and black victims. About age, there is a predominance of minors and a predominance of cases that occur in the family environment. Conclusion: From the data analyzed, we observed that Campos dos Goytacazes follows part of the national standards and the scientific literature regarding rape, occurring predominantly with women, minors and in the family environment, however, in the city there is a prevalence of crime with white women, while nationally there is a predominance of blacks and browns. Also, there was a decrease in reports of domestic violence, which may have occurred due to different factors.
AUTOEROTIC ASPHYXIA – WHEN SHAME TAKES THE SCENE
Authors: Durão Carlos
Published: June 2023

Autoerotic death is defined as accidental death that occurs during individual and solitary sexual activity in which some type of instrument or apparatus was used to increase the victim’s sexual stimulation leading to an unintentional death. We present the autopsy report of a 50-year-old man presented for autopsy with a history of suicide by hanging. The characteristics of the victim’s clothes, the semen stains on the clothes, with the presence of toilet paper next to them, suggesting masturbation and the absence of a hanging groove due to protective foam used by the victim, allowed the reconstitution of the probable mechanism produced by the victim in his asphyxia with the help of a rope and an elastic band attached to the heel of a high shoe, which, when broken, would have produced the fatal accident. The description of this case is important to alert to the concept of autoerotic death and avoid the misinterpretation of the legal medical etiology, allowing accidental cases to be interpreted as suicides, or even natural deaths to be interpreted as autoerotic deaths without fitting into the concept of autoerotic death, which must always be an accidental death. Keywords: autoerotic death, autoerotic asphyxia, autopsy.
REACTION KINETICS OF ACETIC ACID WITH ETHANOL TO ETHYL ACETATE WITH SULFURIC ACID CATALYST
Authors:   Institut Sains dan Teknologi AKPRIND Yogyakarta,Indonesia, Yuniwati Murni , Kusmartono Bambang ,   Institut Sains dan Teknologi AKPRIND Yogyakarta,Indonesia, Yusuf Muhammad ,   Institut Sains dan Teknologi AKPRIND Yogyakarta,Indonesia, Yoga Raditya ,   Institut Sains dan Teknologi AKPRIND Yogyakarta,Indonesia
Published: June 2023

Ethyl acetate is an ester of ethanol and acetic acid. This compound is a colorless liquid with a characteristic odor. Ethyl acetate is widely used as a solvent because of its high solubility. The manufacture of ethyl acetate (ethyl ester) is referred to as the esterification process. This esterification reaction is an exothermic reaction, is reversible and generally runs very slowly so it requires a catalyst to obtain maximum ester. Domestic demand for ethyl acetate is increasing, while production in Indonesia is still lacking. Reactor design requires a reaction mechanism and kinetic data in the form of reaction rate equations and reaction rate constants. This study aims to determine the kinetics of the etherification of acetic acid presented in the form of the reaction rate equation, the value of the reaction rate constant, and the reaction equilibrium constant. In addition, this research also studied how the influence of sulfuric acid catalyst on the reaction rate constant and the reaction balance. The esterification reaction was carried out in a batch reactor. 99% acetic acid and H2SO4 catalyst whose concentrations are varied, are mixed in a reactor equipped with a magnetic stirrer which is operated at 400 rpm, then 96% ethanol is poured with a volume ratio of 1:1 to acetic acid, 5 mL of sample is taken to analyze the remaining acid after The reaction takes place, every certain time interval a sample is taken to be analyzed until an equilibrium point is obtained. From the results of this study it can be concluded that the esterification reaction of acetic acid with ethanol to produce ethyl acetate is a second order reaction with the reaction rate equation (-rA) = k1CACB – k2CCCD. By using a reaction temperature of 34oC and a stirring speed of 400 rpm, the best conditions were obtained using a catalyst of 5.3% by volume, with the reaction rate constant to the right (k1) being 0.014 L/(gmol min), the value of the equilibrium constant (K=k1/k2) is 5.51 and the balance conversion is 77%.
Towards the Special Region of Yogyakarta with Pancasila Character Trough the Implementation of Regional Regulation No. 1 Year 2022 of DIY Province
Authors:   Lecturer Faculty of Law Atma Jaya University Yogyakarta, Indonesia., Susilowat Marietta.D , Yoga Adrianus ,   Lecturer Faculty of Law Atma Jaya University Yogyakarta, Indonesia., Apribilli Apribilli ,   Student of Faculty of Law Atma Jaya University Yogyakarta, Indonesia., K. Alexandro ,   Student of Postgraduated Faculty of Law Atma Jaya University Yogyakarta, Indonesia
Published: June 2023

The rise of violence and intolerance that occurred in Yogyakarta has been very disturbing and concerning to the community, especially the citizens of Yogyakarta. These acts of violence will certainly have a negative impact on the city of Yogyakarta as a student city, which is a destination for prospective students and students from various parts of Indonesia to pursue education in Yogyakarta. This research aims to complete models to translate the policies of theYogyakarta Special Region Government, to counteract acts of violence and intolerance that occur in Yogyakarta. The results of the research are expected to be more effective in realizing Yogyakarta as an inclusive city and Pancasila character. This research uses a qualitative method, the approach that will be used is to combine library research with field research. The material object of the policy model that has been carried out by the Yogyakarta Regional Government, the formal object in terms of Pancasila ethics. Pancasila ethics is an effort to understand the concept of Pancasila values in a pluralistic society, so that tolerance and mutualrespect between citizens can be carried out by the people of Yogyakarta.
The Effect of the Company's Cultural Diversity on Restaurant Employees Performance
Authors:   Bulacan State University, Lena Canet,
Published: June 2023

This study looked at how managing organizational cultural diversity affects restaurant employees' performance. The study's main objective is to provide in-depth information about workplace cultural diversity. It seeks to create a precise set of rules to help organizations all over the world embrace cultural diversity. The respondents' demographic profile, including their gender, age, religion, ethnicity, race, and civil status, was successfully evaluated by the researchers using a questionnaire. This information is crucial for assessing the respondents' differences and how those differences affect their performance at work. The Likert Scale Method is used by the researchers to gauge the respondents' level of agreement with each statement provided in order to determine how cultural diversity affects productivity at work. The study explores how cultural diversity affects employees' performance and productivity, how employees view their organization's management strategy for managing cultural diversity, and how employees' experiences with cultural diversity in the workplace. According to the study, women make up the majority of respondents, who are between the ages of 20 and 30, among those who work in restaurants. The majority of respondents, according to the study, are Roman Catholic, Tagalog, and Asian. Regarding their civil status, all of the respondents are single. On the other hand, the majority of respondents considered their restaurant fosters teamwork by allowing diverse employees to share ideas and knowledge in order to find the best way to solve a problem, resulting in a better outcome on tasks. When it comes to respondents' level of agreement, the majority of respondents believe that organizational cultural diversity benefits restaurant employees' productivity. According to the study's findings, cultural diversity management training or education may enhance workers' performance at work. They will be better able to identify their own strengths and weaknesses if they have an understanding of cultural diversity. When a workplace is managed effectively, it promotes the growth of new ideas, knowledge, abilities, and working methods. The success and profitability of an organization are also influenced by cultural diversity, and productivity is increased in an environment free from cultural prejudice.
Kur’ân’ın Secili Söz Dizgelerinin 7. Yüzyıl Arapların Lügavî Örf ve Âdetleriyle Diyalektik İlişkisi
Authors: DİNDİ Emrah
Published: June 2023

Kur’ân’ın en temel üslup özelliklerinden biri, âyet sonlarında tekrarlanan ve aynı ahengi veren hece, ses, seci ve kafiye uyumlarıdır. Kulağa hoş gelen melodik yapıdaki üstün sanatlı bu söz yapıları, 7. yüzyıl Hicaz bölgesi Arapların bilmedikleri, aşina olmadıkları ve duymadıkları şeyler midir yoksa günlük kelamlarında şifahî ve yazınsal türlerinde mevcut ve maruf lügavî örf ve âdetleri, edebî zevkleri çerçevesinde teşekkül ve tecessüm etmiş ifade kalıpları mıdır? sorusu/sorunu işte bu makalede ele alınmaktadır. Bu amaçla, işte bu çalışma, cahiliye Arapların şifâhî, edebî söylemlerinde secili, uyak ve kafiyeli söz yapılarını tetkik etmekte; ardından kadim İslâmî literatürdeki verilerden hareketle Kur’ân’ın âyet sonlarındaki melodik yapıların, cahiliye Arap şairlerin şiirlerindeki secili, uyaklı edebî ürünlerin özellikleriyle diyalektik ilişkisini ve o dönem Arap toplumunun kelam sonlarında gözetmeyi âdet ve alışkanlık haline getirdikleri seci için, dilin birtakım kıyasî kurallarının terkedilip edilmediğini irdelemektedir. Elbette Kur’ân’ın secili ifade yapılarının o dönem Arapların edebî zevkleriyle diyalektik ilişkisine kadim literatürde satır aralarında zayıf ve cılız bir sesle değinilmiş olsa da ne yazık ki modern dönem çalışmalarında bu konu, henüz irdelenmiş değildir. Bu yüzden özgün ve otantik olduğunu düşündüğümüz bu çalışmanın, alanına katkı sunacağını ümit etmekteyiz. Dolayısıyla literatür taraması yöntemini kullandığımız bu araştırma neticesinde, Kur’ân’ın âyet sonlarındaki birbiriyle uyumlu, ritmik, melodik ses ve vezinli yapılarının 7. yüzyıl Arapların edebî zevkleriyle, lügavî örf ve âdetleriyle ilişkili olup olmadığı, daha doğrusu, bu ifadelerin o günkü Arapların bilmedikleri, aşina olmadıkları harikulâde, tarih üstü, aşkın/müteâl bir dil ve üslupta mı yoksa onların zevk ve beklentilerine muvafık ve mutabık, yerel, mahalli, bölgesel, kültürel antropolojik bir tabiatta mı varlık bulduğu ortaya çıkacaktır.
Teolojide İlişkisellik: Jürgen Moltmann’ın Ekoteolojik Antropolojisinden Hareketle Bir Değerlendirme
Authors: ÖZTÜRK Sevcan
Published: June 2023

Bu çalışma çağdaş teoloji literatürünün merkezi konularından biri haline gelmiş olan ilişkisellik kavramını ele almaktadır. Kavramın din felsefesi ve din felsefesinin irtibatlı olduğu ekoteoloji ve karşılaştırmalı teoloji gibi disiplinler açısından değeri Jürgen Moltmann’ın ekoteolojik antropolojisi çerçevesinde sorgulanmaktadır. Bu çalışma, ilişkiselliğin teoloji alanındaki uygulamalarının din felsefesi ve ilgili disiplinlerin perspektiflerinin zenginleşmesi ve derinleşmesi açısından önemli katkılar sunma potansiyeline sahip olduğunu ve özellikle din felsefesinin de ilişkisel teolojiye kavramsal ve metodolojik katkılar sunabileceğini iddia etmektedir. İlişkisellik, genel anlamda, her şeyin ilişki içinde var olduğu iddiasını merkeze alan yaklaşımdır ve psikoloji, sosyoloji, ekoloji, siyaset bilimi, eğitim, felsefe ve teoloji gibi birçok disiplinde yaygın şekilde uygulanmaktadır. Çağdaş felsefe ve metafizikte en güncel konulardan biri haline gelen ilişkisellik, çağdaş teoloji alanında da, özellikle Hıristiyan teolojisinde, Tanrı, insan ve doğa ilişkisinin farklı boyutlarının tanımlanma-sında yaygın olarak kullanılan bir yöntemdir. Teolojide ilişkisellik, Tanrı’nın, dünyanın ve insanın mahiyetini anlamada ilişkilerin ve birbirine bağlılığın önemini vurgulayan teolojik bir yaklaşım tarzını ifade etmektedir. Günümüz Hıristiyan teolojisinin en etkili isimlerinden olan Moltmann teolojik antropo-lojik görüşlerini, insanın Tanrı’nın suretinde yaratıldığını ifade eden kutsal metin ayetleri etrafında, geleneksel antropolojiye alternatif olarak, ekolojik krizin teolojik boyutları temelinde ve ilişkisel yaklaşım aracılığıyla ortaya koymaktadır. Bu yönüyle Moltmann’ın antropolojisi teolojide ilişkisel yakla-şımın güncel boyutlarıyla ve farklı felsefi ve teolojik disiplinler çerçevesinde ele alınmasında kayda değer bir seçenek olmaktadır. Bu arka plan bağlamında çalışma dört bölümden oluşmaktadır. Birinci bölümde çalışmanın kavramsal çerçevesinin belirgin hale getirilmesi amacıyla teolojide ilişkisel yaklaşıma bir giriş yapılmıştır. Mevcut ekolojik kriz tartışmalarının çağdaş teolojik antropoloji çalışmalarının kapsamında ve odağında değişikliklere sebep olduğu iddiasını ortaya koyan ikinci bölümde çağdaş teolojik antropolojide bir yaklaşım olarak ilişkiselliğin fonksiyonu ve rolü ele alınmıştır. Bu bölümü takiben Moltmann’ın ilişkisel antropolojisi imago Dei doktrinine yaklaşımı etrafında incelenmiştir. Dördüncü ve son bölümde ise, Moltmann’ın yaklaşımlarından hareketle ve onun da ötesinde, teolojide uygulanan ilişkisel yaklaşımın din felsefesi başta olmak üzere bahsi geçen çağdaş teolojik disiplinler açısından doğurması muhtemel sorunlar ve uygulanması neticesinde sunacağı katkılar değerlendirilmiştir.
Arnavutça Kur’an Meali Bağlamında Kādiyânîliğin Mesihlik/Mehdilik Anlayışı
Authors: DURGUTİ Abdylkader
Published: June 2023

Kādiyânîlik, Mirza Gulam Ahmed’in fikirleri çerçevesinde, 19. yüzyılın sonlarında Hindistan’da ortaya çıkmış bir mezheptir. Gulam Ahmed, müceddid, mehdi, mesih ve nebi gibi mesiyanik iddialarla ortaya çıkmıştır. Gulam Ahmed’in kendini kurtarıcı ilan ettiği dönem, İngilizlerin Hindistan’ı işgal etme planları nedeniyle toplumda yaşanan büyük ümitsizlik ve hayal kırıklığının meydana geldiği 18. yüzyıla denk gelmektedir. Gulam Ahmed, cihadın kılıçla değil barışla gerçekleşeceğini söylemiştir. Bunun için de kendisinin Allah tarafından görevlendirildiğini iddia etmiştir.

Gulam Ahmed’in bu iddiaları nedeniyle Kādiyânîlik İslam dünyasında “İslam dışı” bir mezhep olarak ilan edilmiştir. Bu nedenle mezhep taraftarları Hindistan dışında başka ülkelere gitmek zorunda kalmışlardır. Gittikleri yerler arasında Balkan ülkeleri de bulunmaktadır. Balkanlarda Kādiyân Ahmedîlerin izlerine ilk olarak 1929’da rastlanmıştır. Balkanlarda sosyal organizasyonlar, kitap tercümeleri, insani yardımlar ve eğitim gibi birçok alanda faaliyetler yürütmüşlerdir. 1990 yılında Kādiyânî Muhammed Zakaria Khan tarafından Kur’ân Kādiyânî mezhebi görüşleri çerçevesinde Arnavutçaya çevrildi. Bu durum onlar için dönüm noktası olmuştur. Khan, bu mealiyle Balkanlarda Kādiyânî mezhebinin önemli bir şahsiyeti haline gelmiştir. Bu çalışmada Khan’ın, Kādiyânî mezhebinin mehdilik ve mesihlik konuları açısından yorumladığı ayetler ele alınmaktadır. O, söz konusu ayetlerde Gulam Ahmed’in mehdi ve mesih olduğunu ispat etmeye çalışmaktadır. Yöntem olarak Kādiyânî kaynakları ve konuyla ilgili bilgi veren klasik İslam kitapları kullanılmıştır.