bluuebunny/crossref_metadata_2025 huggingface dataset:
Hepatitis B surface antigen-negative but hepatitis B envelope antigen-positive false occult hepatitis B virus infection: A case report
Authors: Yang Shu-Sheng , Fu Fei , Xuan Qian-Kun , Zhang Zhou-Xiang , Li Zhi-Jun , Li Guang-Bo , Yu Xiao-Yu
Published: October 2024

BACKGROUND

Occult hepatitis B infection (OBI) is characterized by the detection of hepatitis B virus (HBV) DNA in serum (usually HBV DNA < 200 IU/mL) or the liver but negativity for hepatitis B surface antigen (HBsAg). The diagnosis of OBI relies on the sensitivity of assays used in the detection of HBV DNA and HBsAg. HBsAg assays with inadequate sensitivity or inability to detect HBV S variants may lead to misdiagnosis of OBI in people with overt HBV infection.

CASE SUMMARY

We report a HBsAg-negative but hepatitis B envelope antigen-positive patient who had a significant HBV DNA level. The patient was initially diagnosed as having OBI. However, sequence analysis revealed a unique insertion of amino acid residues at positions 120-124 in the S protein, which affects the formation of a disulfide bond that is associated with the formation of a loop. It is well known that there is an overlap between the S protein and Pol protein. We found that this new insertion site occurred in polymerase/reverse transcriptase domain, indicating that this insertion might be involved in HBV pathogenicity. The patient was finally diagnosed with a false OBI.

CONCLUSION

An insertion of amino acid residues at positions 120-124 of the S protein affects the formation of immunodominant epitopes and results in negative HBsAg levels.
Suppression of hepatic steatosis in non-alcoholic steatohepatitis model by modified Xiaoyao San formula: Evidence, mechanisms and perspective
Authors: Eid Nabil , Bhatnagar Payal , Chan Li-Li , Garcia-Macia Marina
Published: October 2024

In this letter, we comment on a recent publication by Mei et al , in the World Journal of Hepatology , investigating the hepatoprotective effects of the modified Xiaoyao San (MXS) formula in a male rat model of non-alcoholic steatohepatitis (NASH). The authors found that MXS treatment mitigated hepatic steatosis and inflammation in the NASH model, as evidenced by the reduction in lipid droplets (LDs), fibrosis markers and lipogenic factors. Interestingly, these hepatoprotective effects were associated with androgen upregulation (based on metabolomics analysis of male steroid hormone metabolites), adenosine 5’-monophosphate-activated protein kinase (AMPK) activation, and restoration of phosphatase and tensin homolog (PTEN) expression. However, the authors did not clearly discuss the relationships between MXS-induced hepatic steatosis reduction in the NASH model, and androgen upregulation, AMPK activation, and restoration of PTEN expression. This editorial emphasizes the reported mechanisms and explains how they act or interact with each other to reduce hepatic steatosis and inflammation in the NASH model. As a perspective, we propose additional mechanisms (such as autophagy/lipophagy activation in hepatocytes) for the clearance of LDs and suppression of hepatic steatosis by MXS in the NASH model. A proper understanding of the mechanisms of MXS-induced reduction of hepatic steatosis might help in the treatment of NASH and related diseases.
Zinc deficiency in ruminants and its management: A brief review
Authors: Yanuartono Yanuartono , Indarjulianto Soedarmanto , Paryuni Alsi Dara
Published: October 2024

Minerals are organic substances found in nature and living things. In ruminants, minerals are one of the crucial components of the body. One of the mineral elements that is very important for the body is Zinc (Zn). The prominent role of Zn in ruminants is the synthesis and degradation of carbohydrates, fats, proteins, and nucleic acids. Ruminants can experience Zn deficiency by showing clinical symptoms such as dermatitis, anorexia and parakeratosis, stunted growth, and nail damage. In contrast, ruminants can also experience Zn poisoning with various clinical symptoms such as general weakness, diarrhea, hemolytic anemia, and decreased body weight. Current Zn deficiency can be overcome by adding commercial supplement products containing Zn. This paper aims to add brief insights into the benefits and treatment of Zn deficiency in ruminants.
Challenges Facing Children Reintegration in Uasin Gishu County, Kenya
Authors: O. Abu Willice , G. Onsarigo Thomas , N. Adeli Scholastic , Ochieng Felix , Musyoka Miriam , Ogutu Jeniffer
Published: October 2024

This study sought to establish challenges facing children reintegration in Uasin Gishu County, Kenya. The study used a sequential mixed method approach. The population included reintegrated children and community members within the Uasin Gishu County. The sample included 32 respondents from Ainabkoi, 46 from Kapseret, 36 from Kesses, 42 from Moiben and 54 from Soy sub-counties. Instruments for data collection were questionnaire Focus Group Discussion guide and an in-depth interview guide. The quantitative data was analysed through descriptive statistics. Qualitative data was transcribed, categorized into themes and then analysed through content analysis approach. The study concludes that lack of prior reintegration visits and non-adherence to government guidelines on children reintegration inhibited warmer reception to the returning children. Cultural-related challenges, settling in a new environment and protection and safety-related concerns existed as challenges but in low intensity. Some of the recommendations are that CCIs/CBOs be encouraged to follow the guidelines set out by the government of Kenya. Following the guidelines will guarantee meaningful participation of children, families and the community in the reintegration process. Finally, the Government of Kenyan should re-examine its social safety initiatives towards vulnerable households.
Analisis Pengendalian Kualitas Produk Tahu dengan Pendekatan Metode Six Sigma Dmaic di Pabrik Tahu Abc Karawang
Authors: Suhartinah Siti , Wiyatno Tri Ngudi , Darmawan Heru
Published: October 2024

Pabrik Tahu ABC, Karawang, yang didirikan pada tahun 2010 oleh Bapak H. Muhamad. Penelitian ini berfokus pada pengendalian kualitas produk tahu, terutama dalam hal cacat produksi yang terjadi pada periode Juni 2024. Jenis cacat produk pada Pabrik Tahu ABC adalah cacat tahu kotor, ukuran tahu yang tidak sama, warna tahu yang berbeda dan tekstur tahu yang lembek Melalui analisis data produksi dan cacat, ditemukan bahwa jenis cacat terbanyak adalah warna tahu sedikit menguning dengan total 14.358 pcs. Langkah-langkah perbaikan dilakukan dengan pendekatan metode six sigma DMAIC (Define, Measure, Analyze, Improvement, dan Control). Berdasarkan analisis digunakan pula diagram SIPOC, Critical to Quality (CTQ), dan metode pengendalian kualitas seperti DPMO, peta kendali, diagram Pareto, serta fishbone. Setelah implementasi perbaikan pada Juli 2024, terjadi penurunan jumlah produk cacat dari 48.481 pcs menjadi 29.459 pcs. Usulan perbaikan meliputi penerapan Standar Operasional Prosedur (SOP), perawatan mesin, dan peningkatan kualitas bahan baku. Pengawasan ketat dan dokumentasi berkelanjutan diterapkan untuk memastikan perbaikan kualitas yang konsisten.
Marketing Management: Education Business Strategi Marketing Universitas Swasta Studi Kasus Universitas Kristen Satya Wacana
Authors: Saroinsong Anggreani Sarah Yonaha
Published: October 2024

This research aims to provide theoretical benefits by developing science and theory regarding SWOT analysis and the promotion mix of Satya Wacana Christian University (UKSW), as well as adding literature for further research. The type of research that will be used by the researcher is a qualitative approach and qualitative research. The researcher uses a qualitative approach with a type of descriptive research. The unit of analysis in this study is SWOT "Satya Wacana Christian University", which is a reference for carrying out promotional activities. In this study, there are 2 research observation units, the Public Relations and Alumni Promotion Bureau as actors and persons in charge of UKSW's "promotion and media used" activities in carrying out promotional activities. The researcher obtained the results that the promotional activities carried out by UKSW were appropriate.
Pengaruh Penggunaan Social Media Marketing dan Content Marketing terhadap Brand Awareness di Institusi Pendidikan
Authors: Ramadhan Fakhrul Hilman
Published: October 2024

The purpose of this study is to evaluate the implementation of social media, content marketing, and brand awareness at the Bandung Culinary Academy and analyze the influence of each and the combination of the two on brand awareness. This research was conducted using an explanatory research approach. In this study, the research object consists of 2 (two) types of variables, namely independent variables and dependent variables. This study uses 2 (two) independent variables, namely the use of social media marketing (X1) and the use of content marketing (X2). The bound variable used in this study is brand awareness (Y). As a result, ATB Bandung has not done social media marketing well, especially in terms of communicating the products offered, but the value of the products offered can be conveyed well to the public. Although the content marketing carried out by ATB Bandung is interactive, relevant, and easy to understand.
Hilirisasi Nikel sebagai Nilai Tambah dalam Penguatan Perekonomian Indonesia
Authors: Tangkudung Auderey G. , Kaseger Jemmi Y.
Published: October 2024

In addition to nickel used for export, the government currently requires the downstreaming of nickel in the country. In addition, the potential of nickel in Indonesia also plays a role in increasing state revenue investment, through smelter investment. Through the nickel export ban policy, the long-term continuity of raw nickel supply for domestic smelter needs is maintained. However, there are problems in the community due to the export ban that affects the selling price of nickel, especially affecting business activities. This paper discusses the extent of nickel downstream policies, the ban on nickel ore exports, the added value obtained and the obstacles faced. The research methods used are exploratory and descriptive methods, data collection for analysis purposes is obtained from various literature, regulations and legislation, media reports and various other relevant secondary data sources. The findings show that nickel downstreaming actually creates an additional impact on the nickel industry. value and pushing nickel prices in a positive direction so as to encourage investors to come to Indonesia so as to strengthen Indonesia's economy in a better direction.
Tingkat Kesejahteraan Pengrajin Tungku Dapur
Authors: Norwilistini Norwilistini , Ulfah Maria
Published: October 2024

Bisnis kerajinan tungku dapur ini pada dasarnya dibatasi oleh modal, bahan baku, dan kesulitan memasarkannya. Pengrajin tungku dapur hanya bergantung pada permintaan pengepul, sehingga sulit bagi mereka untuk membuat produk tungku dapur dengan harga tinggi. Selain itu pembeli lebih tertarik tertarik dengan produk yang lebih modern. Penelitian ini bertujuan untuk menggambarkan kesejahteraan pengrajin tungku dapur di desa Banjar Baru Kecamatan Daha Selatan Kabupaten Hulu Sungai Selatan. Penelitian ini merupakan penelitian lapangan atau field research dengan menggunakan pendekatan deskriptif kualitatif. Subjeknya adalah para pengrajin tungku dapur, objeknya adalah kesejahteraan pengrajin tungku dapur. Sedangkan sumber datanya adalah responden dan informan dari berbagai pihak terkait. Hasil penelitian menunjukkan bahwa kesejahteraan pengrajin tungku dapur di desa Banjar Baru Kecamatan Daha Selatan Kabupaten Hulu Sungai Selatan yang masuk kategori keluarga Pra Sejahtera (KPS) berjumlah 3 keluarga. Kategori Keluarga Sejahtera I berjumlah 13 keluarga. Kategori Keluarga Sejahtera II berjumlah 2 keluarga. Dan masuk kategori Keluarga Sejahtera III berjumlah 5 keluarga. Dapat disimpulkan bahwa kesejahteraan pengrajin tungku dapur di desa Banjar Baru Kecamatan Daha Selatan Kabupaten Hulu Sungai Selatan didominasi oleh tahapan Keluarga Sejahtera I. Hal ini membuktikan bahwa para pengrajin tungku dapur belum bisa mencukupi indikator kebutuhan psikologis mereka.
Formulation and Characterization of Moringa Oleifera Nano Particles
Authors: Sharma Shaveta , Kaur Jashanpreet , Singh Jyoti
Published: October 2024

The synthesis of copper oxide nano particles (CuO NPs) using moringa oleifera leaves extract as a green reducing agent has gained significant interest due to its eco-friendly and cost-effective nature. Moringa oleifera leaves extract acts as a reducing agent and capping agent simultaneously, making it a promising alternative to traditional methods. The size, shape, and optical properties of the synthesized CuO NPs can be controlled by varying the concentration of moringa oleifera leaves extract and reaction time. The synthesized CuO NPs exhibit excellent antimicrobial, antioxidant, antiviral, anti-inflammatory and catalytic activities, making them suitable for various applications in bio medicine, wastewater treatment, and energy storage. Overall, the green synthesis of CuO NPs using moringa oleifera leaves extract holds great potential for sustainable and green nanotechnology. FTIR and UV Studies carried out in which it showed that drug-drug and drug-excipients are compatible.
A prevalência de lesões em lutadores de Muay Thai
Authors: Silveira Alexandre Miyaki da , Martins Anna Caroline
Published: October 2024

O Muay Thai, também conhecido como boxe tailandês, é um esporte de contato com constante troca de golpes entre os adversários. Todos os indivíduos praticantes de exercício físico, sendo de forma competitiva ou recreacional, estão sujeitos à ocorrência de lesões, e no caso das lutas e artes marciais, essa ocorrência é aumentada. Este estudo teve como objetivo analisar as principais lesões em atletas de muay thai no Estado do Paraná. A amostra para este estudo foi selecionada conforme o Ranking Paranaense de Muay thai 2019 da Confederação Brasileira de Muay thai e Boxe Tailandês. Foram coletados os dados de 30 atletas, sendo 15 homens e 15 mulheres, com idade média de 24,3 ­± 5,6 anos; praticantes de Muay Thai há 2,7±2,1 anos, que tinham a pontuação maior ou igual a cinco. Foi utilizado o questionário “Lesões no Muay thai” criado e validado por Baptista. Os resultados do estudo mostraram que 93,2% (n=25) sofreram algum tipo de lesão no treinamento ou na competição de Muay Thai, dentre os tipos de lesões mais comuns estão as entorses, fraturas e contusões acometendo principalmente os membros inferiores. Concluiu-se que o alto índice de lesões nos atletas de Muay Thai no Estado do Paraná está associado à participação precoce em competições e consequentemente à falta de preparo físico e técnico.
Proposals for medical guidelines creation at the time of digital transformation of healthcare in Russian Federation
Authors: Prialukhin I. A. , Sheshko E. L. , Seryapina Yu. V. , Plutnitskiy A. N. , Pugachev P. S. , Omelyanovskiy V. V. , Artemova O. R. , Pugacheva T. V. , Dolgushina N. V. , Verhovtsev A. A. , Akhapkina E. S. , Kirpa-Ivanov T. A. , Sukhikh G. T.
Published: October 2024

The article presents the experience of the «National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov» in creation of medical guidelines based on the patient’s route business process for vertically integrated medical information system for “Obstetrics and gynecology” and “Neonatology” (VIMIS “AKiNEO”), with simultaneous digitization of the document, describes the advantages of this an approach before the classical form of writing document.Aim. To conduct a comparative analysis of approaches to writing a medical guideline based on a digitized medical guideline and patient’s route business process for VIMIS “AKiNEO” and in the classical way.Materials and methods. The content of digitized medical guidelines and procedures for the provision of medical care, formed by experts on the basis of the “National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov” with the methodological support of the Center for Healthcare Quality Assessment and Control were used. The assessment of the methodological advantages of writing medical guidelines based on patient routes business processes in comparison with writing in the classical way was carried out using methods of analysis and synthesis.Results. Experts have created 17 patient routes using the content of digitized medical guidelines for immersion in the VIMIS “AKiNEO”. These routes fully reflect the amount and timing of medical interventions necessary to ensure the quality of medical care. Methodological approaches for writing medical guidelines based patient routes business processes have been developed. It has been demonstrated that digitizing the content of medical guidelines and medical care procedures, describing medical guidelines in the form of a business process diagram, identify “zones of uncertainty” that ar e not visible in the text document, and can significantly affec t the quality of medical care to the patient.Conclusion. The creation of regulatory legal acts on the organization and provision of medical care and medical guidelines in modern conditions of healthcare digital transformation should take place after digitizing the text of the document and creating a business process for the patient’s route, which will improve the quality of these documents.
Debatable issues of coding chronic forms of ischemic heart disease as the primary cause of death
Authors: Shepel R. N. , Samorodskaya I. V. , Kakorina E. P. , Drapkina O M.
Published: October 2024

Aim: to examine the opinions of healthcare professionals on using codes from the ICD-10 group chronic ischemic heart disease (CIHD) (I25.0, I25.1, I25.8, I25.9) as the primary cause of death and discuss the results in the context of comparing with regional variability of standardized mortality ratio (SMR) from different forms of CIHD.Materials and methods. A one-stage study was conducted. This article describes the results of a survey of 366 medical workers (cardiologists, internists/general practitioners/family doctors, pathologists, public health and healthcare specialists, paramedics) from 47 subjects of the Russian Federation who fill out a medical death certificate (MDS) more often than 2–3 times a month. In addition, SMR from coronary heart disease were determined based on a brief nomenclature of causes of death of Rosstat in 82 regions of the Russian Federation for 2022.Results. 80.1 % of respondents expressed the opinion that I25.0, I25.1, I25.8, I25.9 are necessary for coding causes of death, but half of those surveyed do not see any differences in them. At the same time, respondents admit the possibility of using these CIHD codes as the primary cause of death without ante-mortem and pathological verification. The relatively small coefficient of variation of SMR overall from CIHD (34.19 per 100,000 population) is associated with high values from its individual forms: the coefficient of variation of average regional SMRs ranged from 62 % for code I25.1 to 174 % for code I25.0.Conclusions. The results of this study indicate a variable attitude of specialists filling out MSD towards choosing ICD-10 codes from the CIHD group, leading to significant interregional differences in CIHD mortality rates. It is necessary to develop unified recommendations describing situations in which codes from the CIHD group can be considered the primary (main) cause of death.
Mood Analysis of COVID-19 Messages: A Systemic Functional Linguistics Approach to Understanding Public Health Communication
Authors: Muhammad Muhammad
Published: October 2024

Purpose: This study examines how Systemic Functional Linguistics (SFL), particularly through mood analysis, can enhance understanding of public health communication related to COVID-19. The aim is to explore the use of mood types in health messages to convey risk, provide instructions, and manage public vulnerability during the pandemic.
Methodology: Utilizing a qualitative and quantitative approach, this study analyzed 100 COVID-19 health messages sourced from government websites, social media, and public health announcements. The messages were categorized according to their mood type imperative (commands) and declarative (statements) to assess their functional roles in conveying public health information. Data were tabulated to illustrate the frequency of each mood type and their implications for public health communication.
Findings: The analysis revealed that 70% of the messages were in the imperative mood, highlighting the urgency of issuing clear directives to the public. In contrast, 30% of the messages were in the declarative mood, providing essential information and reassurance. This distribution indicates a strategic use of language in public health messaging to promote compliance while fostering public trust.
Unique Contribution to Theory, Practice and Policy: This study contributes to the theoretical understanding of SFL mood analysis in public health communication by illustrating how mood types influence public perception and behavior during a crisis. The findings offer practical insights for health authorities to enhance communication strategies, ensuring that messages are both directive and informative. Additionally, this research informs policymakers about effective messaging practices to improve health outcomes during future public health crises.
Contabilidad de costos
Authors: Bonín Campos Edith Vanessa
Published: October 2024

La contabilidad de costos es una disciplina clave para todo tipo de empresa, con una aplicación especialmente relevante en las empresas industriales. 
A través de esta rama contable, es posible conocer con precisión el precio de costo de un producto o servicio, así como también establecer el precio de venta adecuado, considerando un margen de utilidad que sea razonable y competitivo. Este proceso es esencial para la toma de decisiones estratégicas y para la sostenibilidad financiera de las organizaciones en un entorno económico cada vez más dinámico.
Al respecto, la presente publicación se enfoca en los aspectos fundamentales de la contabilidad de costos, proporcionando a los estudiantes las herramientas conceptuales y prácticas necesarias para su correcta aplicación. Las temáticas abordadas a lo largo de los capítulos son las siguientes:
− Capítulo 1: Fundamentos del Costo. Se introduce el concepto de costo y su relevancia dentro de la estructura financiera de una empresa. Este capítulo abarca clasificación de costos, diferenciación entre costos fijos y variables, así como el análisis del costo unitario y su impacto en la toma de decisiones empresariales.
− Capítulo 2: Plan de Cuentas de una Empresa Industrial. En este apartado se examina el diseño y funcionamiento de un plan de cuentas específico para una empresa industrial, detallando categorías contables involucradas en la gestión de costos y su relación con los estados financieros. 
− Capítulo 3: Control y Registro de Inventarios. Se profundiza en las técnicas de control de inventarios, uno de los aspectos más críticos en la contabilidad de costos. Esta sección cubre la importancia del adecuado registro y valuación de inventarios, analizando métodos como el PEPS (primero en entrar, primero en salir) y el UEPS (último en entrar, primero en salir), entre otros.
− Capítulo 4: Los Sistemas de Costeo. Se presentan los diferentes sistemas de costeo utilizados en las empresas, como el costeo por órdenes de producción y el costeo por procesos, destacando las ventajas y desventajas de cada uno en función de las características de la empresa.
En correspondencia, el propósito implica que el estudiante adquiera una comprensión integral sobre la contabilidad de costos, mediante un enfoque didáctico que combina teoría y ejemplos prácticos, facilitando así su aprendizaje y posterior aplicación en situaciones reales.
Al finalizar el estudio de esta asignatura, el estudiante será capaz de analizar, interpretar y aplicar de manera efectiva las herramientas contables en el contexto de la contabilidad de costos. Además, podrá identificar y gestionar los distintos elementos que componen este tipo de contabilidad, contribuyendo al control financiero y a la optimización de los recursos dentro de una empresa.
MsC. Edith Vanessa Bonín Campos Instituto Tecnológico Universitario de Formación (UF)
The Relationship between Financial Technology as one of the Tools of the Industrial Revolution and the Development of Financial and Banking Services
Authors: Hashim Ahmed Amin , Hamed Mohamed S. , Elgebaly Hamdy Goma , Ahmed Sharaf Othman , Abdelfatah Amir Abdelfatah Ramadan
Published: October 2024

The research aims to study the role of financial technology as one of the tools of the industrial revolution in the development of financial and banking services in the Egyptian and Arab business environment, and to achieve this goal, the researcher formulated a set of assumptions, perhaps the most important of which is ” there is no statistically significant impact of financial technology on the development of financial and banking services “and also” there is no statistically significant impact of financial technology positively on the process of financial inclusion”, and to test these assumptions, a set of statistical methods were used to serve the preparation of a field study in order to achieve research purposes, and that study resulted in a set of results, the most important of which were there is a significant effect Statistics of financial technology in the improvement and development of financial and banking services and the economic work environment through the provision of innovative tools of digital financial services, which leads to an increase in the funds available for lending and through lending platforms, which contributes to the financing of small and medium enterprises. Considering these results, a set of recommendations was presented that the researcher hopes to contribute to maximizing the benefits of financial technology for companies, banks, and organizations and directing financial information flows toward further development in this field with the need to establish regulations and laws to hedge the risks associated with digital transformation and applications of financial technology
Ambientes, personas y conductas sustentables
Authors: Corral Verdugo Víctor
Published: October 2024

El presente texto plantea que las soluciones a los problemas ambientales que nos aquejan deben seguir una estrategia integral. Dentro de este esquema, las nociones de individualidad, otredad y metapersonalidad —integrados en la conciencia humana— juegan un papel fundamental. Apoyándose en datos duros de la literatura científica, el libro argumenta que las personas no son solo individuos diferentes de otros, sino también personas en interdependencia con las demás y pertenecientes al mundo natural. También analiza la conjugación de explicaciones psicológicas, contextuales, disciplinarias e interdisciplinarias para comprender los graves problemas que la humanidad ha ocasionado en la biosfera terrestre, y perfilar una solución más efectiva.
A Pilot Study of Deep Learning-Based Monocular Depth Estimation from Fundus Photographs
Authors: Gelman Rony , Abràmoff Michael D.
Published: October 2024

The purpose of this study was to evaluate the feasibility of a generalizable deep-learning (DL) based system with no a priori knowledge of fundus photographs to generate monocular depth map information about optic disc structures from this imaging modality. Images of 30 stereo pairs of fundus photographs centered on the optic disc of 30 subjects were analyzed with this DL system to generate monocular depth maps using zero-shot cross-dataset transfer. These maps were registered onto reference standard depth maps derived from Optical Coherence Tomography. Accuracy of the DL system was assessed by the root of mean squared error (RMSE) between the estimate and reference standard. 47% of the total images from the dataset were successfully processed, with mean RMSE of 0.081. Our findings demonstrate that single image, monocular depth estimation with a generalizable DL system using zero-shot cross-dataset transfer applied to retinal color fundus photographs is feasible and has potential.
 
Received: 24 July 2024 | Revised: 30 September 2024 | Accepted: 10 October 2024
 
Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
 
Data Availability Statement
The data that support the findings of this study are openly available in Iowa Carver College of Medicine at https://medicine.uiowa.edu/eye/inspire-datasets, reference number [15]; in Github at https://github.com/isl-org/MiDaS, reference number [18]; in PyTorch at https://pytorch.org/tutorials/beginner/transfer_learning_tutorial.html, reference number [19]; in ImageJ Docs at https://imagej.net/software/imagej2/, reference number [23].
 
Author Contribution Statement
Rony Gelman: Conceptualization, Methodology, Software, Validation, Formal analysis, Investigation, Resources, Data curation, Writing - original draft, Writing - review & editing, Visualization, Supervision, Project administration. Michael D. Abràmoff: Writing - original draft, Writing - review & editing, Visualization, Supervision, Project administration.
К ПРОБЛЕМЕ ПЕРЕРАБОТКИ ОТВАЛЬНЫХ ШЛАКОВ МЕДЕПЛАВИЛЬНЫХ ЗАВОДОВ КАЗАХСТАНА
Authors: Баимбетов Б.С. , Тажиев Е.Б. , Молдабаева Г.Ж. , Даулетбакова А.А.
Published: October 2024

Дана характеристика отвальным медным шлакам, рассчитан их рациональный состав. Для эффективной переработки подобных шлаков предложено применение процесса выщелачивания растворами серной кислоты, не требующего затрат тепловой энергии извне, вследствие экзотермичности протекающих реакций. Выполнен расчет термодинамических характеристик реакций, возможных при выщелачивании отвальных медных шлаков растворами серной кислоты. Проведен анализ фазового равновесия процесса выщелачивания шлака при различных расходах серной кислоты, оценено влияние температуры на изменение состава фаз, построены диаграммы фазового равновесия. Выполнены исследования по сернокислотному выщелачиванию отвальных медных шлаков при комнатной температуре и при 80 °С. Выявлены проблемы сгущения и фильтрования пульпы после выщелачивания, связанные с образованием кремниевой кислоты

Үйінді мыс шлактарына сипаттама беріліп, олардың рационалды құрамы есептелді. Мұндай шлактарды тиімді өңдеу үшін жүретін реакциялардың экзотермиялық болуына байланысты жылу энергиясының сырттан шығынын қажет етпейтін күкірт қышқылының ерітінділерімен шаймалау процесін қолдану ұсынылады. Үйінді мыс шлактарын күкірт қышқылының ерітінділерімен шаймалау кезінде мүмкін болатын реакциялардың термодинамикалық көрсеткіштері есептелді. Күкірт қышқылының әр түрлі шығындарында шлакты шаймалау процесінің фазалық тепе-теңдігіне талдау жүргізіліп, температураның фазалар құрамының өзгеруіне әсері бағаланды, фазалық тепе-теңдік диаграммалары тұрғызылды. Үйінді мыс шлактарын бөлме және 80 °С температураларда күкірт қышқылымен шаймалау бойынша зерттеулер жүргізілді. Кремний қышқылының түзілуіне байланысты шаймалаудан кейін пульпаның қоюланып сүзуге кедергі жасайтыны анықталды

The characteristic of dump copper slag is given, their rational composition is calculated. For the effective processing of such slags, it is proposed to use the leaching process with sulfuric acid solutions, which does not require the expenditure of heat energy from outside, due to the exothermicity of the ongoing reactions. Calculation of thermodynamic characteristics of reactions possible at leaching of waste copper slags with solutions of sulphuric acid is carried out. The phase equilibrium of the slag leaching process was analysed at different sulphuric acid flow rates and the influence of temperature on the change of phase composition was evaluated, phase equilibrium diagrams were constructed. Studies on sulfuric acid leaching of waste copper slag at room temperature and at 80 °C. Problems of pulp thickening and filtration after leaching associated with the formation of silicic acid have been identified
РАЦИОНАЛЬНЫЕ ПАРАМЕТРЫ БВР, ОБЕСПЕЧИВАЮЩИЕ НАИМЕНЬШИЕ ЗАТРАТЫ НА ДОБЫЧУ И ПЕРЕРАБОТКУ РУДЫ
Authors: Орынбай А.А. , Алибаев А.Е. , Ибырханов Т.С.
Published: October 2024

Отгрузка разрушенной горной массы требуемого качества и количества на обогатительную фабрику является одной из основных задач подготовительных работ при добыче полезных ископаемых. Основным способом регулирования этого процесса является оптимизация параметров и технологий ведения буровзрывных работ. На Актогайском месторождении возникла проблема с увеличением крепости добываемой руды по мере углубления карьера, что сильно влияет на производительность обогатительной фабрики. В статье приведен опыт проведения мероприятий по оптимизации БВР для улучшения работы обогатительной фабрики, а точнее стабилизации процесса первичного дробления руды. В статье приведены методы расчета рациональных параметров и результатов БВР. Проведен расчет рациональных параметров БВР, а также расчет гранулометрического состава взорванных пород при рациональных параметрах и при предложенных для экспериментальных взрывов

Қажетті сападағы және көлемдегі бұзылған тау жынысын байыту фабрикасына жөнелту пайдалы қазбаларды өндіруге дайындық жұмыстарындағы негізгі міндеттердің бірі болып табылады. Бұл процесті реттеудің негізгі әдісі бұрғылау-жару жұмыстарының параметрлері мен технологияларын оңтайландыру болып табылады. Ақтоғай кен орнында карьердің тереңдеуімен өндірілетін кеннің беріктігінің артуы проблемасы туындады, бұл байыту фабрикасының өнімділігіне айтарлықтай әсер етеді. Мақалада байыту фабрикасының жұмысын жақсарту, дәлірек айтқанда, кенді бастапқы ұсақтау процесін тұрақтандыру мақсатында бұрғылау-жару жұмыстарын оңтайландыру шараларын өткізу тәжірибесі баяндалған. Мақалада бұрғылау-жару жұмыстарының ұтымды параметрлерін есептеу әдістері және нәтижелері келтірілген. Бұдан басқа, ұтымды параметрлерге және эксперименттік жарылыстар үшін ұсынылған параметрлерге сәйкес жарылған жыныстардың гранулометриялық құрамын есептеу жүргізілді

One of the main tasks of preparatory work in mineral extraction is the delivery of the required quality and quantity of broken rock mass to the processing plant. The primary method of regulating this process is optimizing the parameters and technologies of drilling and blasting operations. At the Aktogay deposit, a problem has arisen with the increasing hardness of the mined ore as the pit deepens, significantly affecting the performance of the processing plant. The article presents the experience of implementing measures to optimize drilling and blasting operations to improve the performance of the processing plant, specifically to stabilize the primary ore crushing process. The article provides methods for calculating rational parameters and results of drilling and blasting operations. Calculations were made for the rational parameters of drilling and blasting operations, as well as for the granulometric composition of blasted rock under rational parameters and those proposed for experimental blasts
EDUCAÇÃO POPULAR EM SAÚDE ENQUANTO POLÍTICA SOCIAL EMPREGADA NO COMBATE A DESINFORMAÇÃO RELACIONADA A IMUNIZAÇÃO DA COVID-19
Authors: Aguilar Antonio Marcos Moreira , Teixeira Ranielle Meire Ramos , Lima Monia Maia de
Published: October 2024

Objetivo: demonstrar a importância da educação popular no combate as fake news relacionadas a imunização pela Covid-19. Metodologia:  estudo de revisão rápida, com delineamento qualitativo exploratório, realizado entre junho a julho de 2023. As bases de análise foram a Cochraner Library, Pubmed, McMaster University, PIE e Epistemonikos. As evidências foram exportadas e analisadas pelo gerenciador Rayyan QCRI. Os artigos foram analisados de acordo com título, autores, objetivos, tipo de estudo, métodos, desfechos encontrados, intervenções, conclusões e limitações do estudo. A qualidade metodológica dos artigos incluídos foi avaliada pelo software online robvis. Resultados: foram compilados 252 artigos, sendo 110 excluídos na etapa da pré seleção, Na sequência, 142 trabalhos foram analisados em duplicidade por título e resumo, tendo 127 exclusões por imcompatibilidade com a pergunta de pesquisa. Na etapa posterior, 17 artigos foram lidos em sua integralidade, sendo incluídos na análise final dois estudos. Conclusão: os artigos selecionados se apresentaram como de baixa qualidade. Embora o tema proposto seja recente, foi possível elencar publicações na literatura que embasam e reforçam a relevância da educação popular em saúde no âmbito social e comunitário.
Naturfasereigenschaften als Frühindikator für Verbundwerkstoffeigenschaften
Authors: Gries Thomas , Möbitz Christian , Bröning Jonas
Published: October 2024

Die Beachtung von Emissionsstandards und eine nachhaltigere Ressourcennutzung sind für die moderne Wirtschaft und Gesellschaft von essenzieller Wichtigkeit. Naturfasern stellen eine bedeutende natürliche Ressource dar, die seit jeher in der menschlichen Nutzung steht. Durch ihre während der Nutzung negative CO2-Bilanz und den niedrigen Energiebedarf bei der Verarbeitung können Natur­fasern einen wesentlichen Beitrag zur Reduzierung der globalen Treib­hausgasemissionen leisten. Insbesondere in der Anwendung bei technischen Textilien und Verbundmaterialien zeigen Natur­fasern aufgrund ihrer geringen Dichte und damit verbundenen hohen spezifischen Festigkeit und Steifigkeit ein hohes Einsatzpotenzial.
Pringles-Chips kehren zurück in die Edeka-Regale
Authors: Mende Jan , Fries Tanja , Sachsenröder Delphine
Published: October 2024

Kellanovas Stapelchips sollen schon im November wieder in die Filialen kommen. Der Hersteller bezeichnet die Einigung als ersten Schritt.
Biermarkt erholt sich nur kurz
Authors: Brück Mario
Published: October 2024

Im rückläufigen deutschen Biermarkt schlagen sich die großen Marken 2024 wacker. Nur Marktführer Krombacher verliert bisher Umsatz und Menge.
Fressnapf muss umplanen
Authors: Klug Denise
Published: October 2024

Nachdem Tech-Lieferant Enfore Insolvenz angemeldet hat, muss Fressnapf Teile der IT neu aufstellen. Das verzögert die Umsetzung der Omnichannel-Vision des Tierbedarfhändlers.
Städter stehen auf digitale Werbung
Authors: Nusser Bernd
Published: October 2024

Stadtbewohner suchen häufiger nach Lebensmittelangeboten, sind von einem Übermaß an Kommunikation aber auch eher genervt als die Landbevölkerung.Gezieltes Geo-Marketing werde für Händler immer wichtiger, sagen die Studienautoren.
„Attraktivität ist Kernthema“
Authors: Wittenhagen Julia
Published: October 2024

Seit 2000 ist Peter Stahl im Vorstand der Familienkäserei Hochland. Auf seine Initiative hin wird über Great Place to work regelmäßig Feedback von den mehr als 6000 Mitarbeitern in sieben Ländern eingeholt, davon 2300 in Deutschland und 1300 in Russland. Denn für den CEO ist Arbeitgeber- attraktivität der Schlüssel zur Zukunft. „Operative Herausforderungen durch Arbeitskräftemangel“ sind sogar im Geschäftsbericht Thema.
Uruguay erfüllt Vorgaben
Authors: Schindler Barbara
Published: October 2024

Mehr als dreimal so viele Rinder wie Menschen leben in Uruguay. Sie stellen als bedeutendes Exportgut einen wichtigen Wirtschaftsfaktor dar.
Franuí kombiniert gefrorenes Obst und Schokolade
Authors: Schindler Barbara
Published: October 2024

Himbeeren im Schokomantel aus dem TK-Regal: Vertriebspartner Uplegger Food Company will möglichst viele Verbraucher das innovative Produkt probieren lassen, um sie zu überzeugen.
Unibán verkürzt Transportzeiten
Authors: Schindler Barbara
Published: October 2024

Neben kolumbianischen Bananen aus der fruchtbaren Region Urabá setzt Unibán strategisch verstärkt auf verarbeitete Früchte und Avocados.
Dole diversifiziert Erzeugung und Angebot
Authors: Schindler Barbara
Published: October 2024

Vertrauen und stabile Partnerschaften sind die Basis für Doles Position als einer der führenden Fruchtvermarkter der Welt.
Von Start-ups zu Key Playern
Authors: Frutig Markus
Published: October 2024

Die SPS als traditionelles Automatisierungshighlight zum Jahresende findet vom 12. bis 14. November 2024 statt. Diese internationale Erfolgsplattform wird von Interessenten und Ausstellern aus aller Welt seit mehr als drei Jahrzehnten frequentiert. Und auch in diesem Jahr gibt es allen Grund für einen Wiederholungsauftritt. 25 Schweizer Automations-Unternehmen sind auch mit dabei in Nürnberg.
Am Binnenmarkt orientiert
Authors: König Inge
Published: October 2024

Allensbach. Die Rangliste der Top-50-Unternehmen im Agrarhandel zeigt deutlich, dass die Branche stark am Binnenmarkt orientiert ist.
Food-Lab-Update
Authors: Deininger Olaf
Published: October 2024

Frankfurt a.M. Der Überblick zu den aktuellen Aktivitäten der FoodLabs in Deutschland und Europa.
Antriebe bei der Bierproduktion: Modernes Brauen
Authors:   Gunthart Mau
Published: October 2024

Für die gewünschte Steigerung der Produktionskapazität einer Klosterbrauereimussten die Betreiber eine neue, energieeffiziente Anlage installieren. DasProjekt war seinerzeit die erste Anlage mit dezentraler Technik, die Antriebspezialisten aus Bruchsal für eine Brauerei in Deutschland installierten.
The Pathogenicity of Aspergillus Fumigatus and Aspergillus Niger Isolated from Accumulated Poultry and Goat Droppings in Immuno-Competent Albino Mice
Authors: Okafor Ugochukwu Chisom , Aniekwu Chijioke Christian , Anene Nzube Victor , Onyeneho Vitus Ikechi
Published: October 2024

The pathogenicity of Aspergillus fumigatus and Aspergillus niger isolated from poultry and goat droppings in immuno competent albino mice was investigated. A total of 12 soil samples of both poultry and goat droppings were collected and screened for the presence of Aspergillus fumigatus and Aspergillus niger using microbiological standard method. The pathogenicity of the isolates on immuno-competent albino mice were investigated by challenging the mice subcutaneously using 0.5 ml of the inoculum. All mice were kept under complete observation for four (4) weeks for pathological signs and symptoms, mortalities and gross morphological lesions of the internal organs were observed and recorded. The study revealed that the total mean plate count of Aspergillus fumigatus was higher than that of Aspergillus niger and also, there were significant pathological lesions among some organs of the infected mice after a pathological cross examination. Thus, the result of the examination shows that congestion, haemorrhage, air sacculitis, pericarditis, perihepatitis and hypertrophy were observed from the immuno-competent mice under study. The obvious pathological features of these fungi on immuno-competent albino mice shows invariably that they can pose a high level life-threatening infections in immuno-compromised individuals particularly farmers handling the animals. Thus, there is need for good healthy hygiene practices, maintenance of environmental sanitation and managing the environmental factors that supports the multiplication of these fungal infections.
Revolutionizing Computer Science Education: Integrating Blockchain for Enhanced Learning and Future Readiness
Authors: Chris Gilbert  , Mercy Abiola Gilbert
Published: October 2024

Abstract: This research investigates the transformative potential of incorporating blockchain technology into computer science education. In light of the rapid evolution of the digital landscape, traditional educational frameworks often fail to meet the demands of the industry, resulting in a significant skills gap among graduates. This paper analyzes how the integration of blockchain can revolutionize computer science curricula by enhancing learning experiences and equipping students to navigate future technological challenges. The study highlights the advantages of blockchain in educational contexts, including increased security and transparency of academic records, streamlined credentialing processes, and the establishment of decentralized learning platforms that promote collaboration and innovation. It presents case studies of institutions that have successfully implemented blockchain, along with strategies for educators to effectively integrate this technology into their pedagogical approaches. Additionally, the research addresses the challenges and limitations associated with blockchain integration, such as the requisite learning curve and infrastructure demands. The findings indicate that the incorporation of blockchain in computer science education can significantly boost student engagement, provide verifiable skill sets, and align academic outcomes more closely with industry requirements. This study contributes to the ongoing discourse on educational innovation and offers a strategic framework for institutions aiming to utilize blockchain technology in preparing students for the future job market.
Ether and ester formation from peroxy radical recombination: a qualitative reaction channel analysis
Authors: Franzon Lauri , Camredon Marie , Valorso Richard , Aumont Bernard , Kurtén Theo
Published: October 2024

Abstract. The least volatile organic compounds participating in atmospheric new-particle formation are very likely accretion products from self- and cross-reactions of peroxy radicals (RO2). It has long been assumed that the only possible accretion product channel in this reaction is that forming a peroxide (RO2+RO2→ROOR+O2), but it has recently been discovered that a rapid alkoxy radical (RO) decomposition may precede the accretion step of the mechanism, forming slightly fragmented but more stable ether (ROR) or ester (RC′(O)OR) accretion products. In this work, the atmospheric implications of this new reaction channel have been explored further by using a modified version of the Generator for Explicit Chemistry and Kinetics of Organics in the Atmosphere (GECKO-A) software to generate a large amount of representative RO2 + RO2 reactive pairs formed from the oxidation of typical primary hydrocarbons and by applying structure–activity relationships (SARs) to predict the potential accretion products. These data are analysed in terms of the formation of low-volatility products, and new discoveries are presented on what types of RO2 are especially efficient (and which are surprisingly inefficient) at forming accretion products. These findings are discussed in terms of the atmospheric relevance of these new RO2 + RO2 reaction channels. As the generation of these data rests on several simplifications and assumptions, many open questions worthy of later studies are also raised.
Predicting hygroscopic growth of organosulfur aerosol particles using COSMOtherm
Authors: Li Zijun , Buchholz Angela , Hyttinen Noora
Published: October 2024

Abstract. Organosulfur (OS) compounds are important sulfur species in atmospheric aerosol particles, due to the reduction of global inorganic sulfur emissions. Understanding the physicochemical properties, such as hygroscopicity, of OS compounds is important for predicting future aerosol–cloud–climate interactions. However, their hygroscopicity is not yet well understood due to the scarcity of authentic standards. In this work, we investigated a group of OS compounds with short carbon chains (C1–C5) and oxygen-containing functional groups in the form of sodium, potassium, or ammonium salts and their mixtures with ammonium sulfate. The hygroscopic growth factors (HGFs) of these OS compounds have been experimentally studied. Here, the HGFs were calculated from mass fraction of water that was computed using the conductor-like screening model for real solvents (COSMO-RS). A good agreement was found between the model-estimated and experimental HGFs for the studied OS compounds. This quantum-chemistry-based approach for HGF estimation will open up the possibility of investigating the hygroscopicity of other OS compounds present in the atmosphere.