bluuebunny/crossref_metadata_2025 huggingface dataset:
Políticas públicas de promoción de la autogestión cooperativa de la Alianza Cambiemos
Authors: Hudson Juan Pablo
Published: May 2021

Se analizan en este artículo las continuidades y rupturas introducidas durante 2016 y 2017 por el gobierno nacional en la implementación del Programa de Trabajo Autogestionado (Ministerio de Trabajo) y del Programa de Ingreso Social con Trabajo (Ministerio de Desarrollo Social). La Alianza Cambiemos utilizó una sólida estructura estatal de creación de empleo a través del asociativismo que había permitido asistir, entre 2003 y 2015, a informales y desempleados crónicos. En la primera mitad del mandato incrementó los presupuestos, eliminó el requisito de que los reclamantes se organicen en cooperativas para obtener subsidios, exaltando la figura del individuo emprendedor, y fortaleció el poder económico-administrativo de las organizaciones sociales. El objetivo fue sostener la asistencia a los excluidos crónicos y contener eventuales conflictos sociales en un crítico escenario económico inducido por sus propias políticas.
Políticas Públicas, MERCOSUR y Educación Superior: la Mercosurización del Estado acreditador
Authors: Solanas Facundo
Published: May 2021

El propósito de este trabajo es dar cuenta de la construcción y continuidad de una política regional en el seno del MERCOSUR y los países asociados, pese a las redefiniciones, los distintos cuestionamientos y crisis por las que atraviesa este proceso de integración. Para ello analizamos la consolidación y expansión de la dinámica de mercosurización del Estado acreditador, retomando trabajos que dan cuenta de la génesis de los primeros instrumentos de políticas públicas regionales, como el Mecanismo Experimental de Acreditación (MEXA) en el MERCOSUR, que en una etapa posterior darían lugar a su traducción en dispositivos permanentes (ARCUSUR), hasta lograr expandirse entre Estados asociados al bloque.
The impact of noise in early childhood settings: A New Zealand perspective
Authors: Bates Susan , Page Wyatt , Stover Sue
Published: May 2021

Excessive noise levels in early childhood centres have a direct impact on the learning of young children, as well as on the wellbeing of teachers. Psycho-acoustic studies show that noise is a key factor contributing to elevated adult stress levels and annoyance, leading to lower levels of adult sensitivity to children’s needs and fewer direct interactions with them. Longer term, local and international research indicates correlations between excessive noise in early childhood education (ECE) centres and health problems, such as to hearing loss, voice strain, obesity, diabetes, and cardiac conditions. Noise as a chaos factor in early childhood settings undermines wellbeing of both adults and children. Because noise negatively impacts on quality relationship and communication, children’s language development is also impacted. Yet noise within New Zealand early childhood settings is under-researched, under-regulated, and under-monitored. Drawing on local and international research and on a survey of New Zealand early childhood teachers, this article recommends regulating for the creation of quieter environments for the benefit of teachers and learners, the adults and children in early childhood settings.
Phraseological picture of the world in the texts of modern mass media
Authors: Odanova Sagira , Nurzhanova Botagoz , Akkozhina Bayan , Kokanova Zharkynai , Sadyrbayeva Bakhytzhamal
Published: May 2021

The article deals with the definition of the phraseological picture of the world, reviews the existing approaches to its study in modern linguistics, and analyzes the objects of existing research that affect the problems of national representation of fragments of the phraseological picture of the world in the minds of native speakers. Also, the article examines the language picture of the world as a subject of study in the theories of modern communication. The article gives an up-to-date description of the content of this concept and its classification on various grounds (based on the object, subject, principles, and methods of language representation). The role of the linguistic picture of the world in the framework of the theory of intercultural and mass communication in semiotic and cognitive research is analyzed. The article further deals with the development and research of the linguistic picture of the world by both foreign and domestic scientists in this field. It describes the influence of the language of mass media on the picture of the world, namely, the work of journalists, where they use phraseology not only as it exists in the language, but also in a modified form, updating the semantics, structure and expressive and stylistic properties of phraseological turns.
Verbal and multimodal metaphorical patterns in Wikipedia migration discourse
Authors: Polajnar Janja
Published: May 2021

The use of metaphors in the refugee discourse since 2015 has so far mostly been explored in newspapers in different EU countries. In this study, we combine linguistic discourse metaphor analysis with a corpus-based approach, complementing qualitative and quantitative corpus evidence from Wikipedia migration corpus to explore verbal and multimodal metaphorical patterns. As a multimodal and multilingual hypertext, Wikipedia, represents a highly relevant source of information and a unique source for the multimodal and cross-linguistic discourse linguistic analysis. In this paper metaphorical expressions are considered as a transtextual discursive phenomenon in the light of Foucaudian tradition. The results of the study show that the analyzed migration discourse in Wikipedia is like the newspaper migration discourse predominantly structured by metaphorical patterns that draw from the source domains water flow/natural catastrophes as well as military/warfare. These source domains are conventionally used in relation to a wide range of target domains (multivalency), however, they play a constitutive role in the analyzed discourse by providing a specific view of events and emphasizing certain aspects and evaluations. The patterning of water flow metaphors across Wikipedia articles and talk pages is in multimodal metaphors extended, elaborated and reinforced in visual mode, referring to those migrating as a flow, wave, influx. However, especially on Wikipedia talk pages Wikipedians point to the dehumanization of those fleeing and the securitization of migration through metaphorical expressions as a problematic linguistic discourse practice
The specifics of the evaluative metaphor in English (based on the texts of art discourse)
Authors: Shorabek Adilkhan , Pazilova Bakiza , Manapova Gulzhan , Tolysbayeva Zhanna , Mansurov Nurlan , Kralik Roman
Published: May 2021

This article deals with a comprehensive description of the evaluativeness of metaphors in modern English. The evaluation criteria underlying the evaluability of metaphors are determined, variations as an object of evaluation and an agent as a donor of evaluation in the semantic structure of metaphors are considered, axiological types of lexical and semantic groups of metaphors are differentiated, and the means and conditions for varying the evaluability of metaphors are systematized. This research paper depicts the pragmatic relevance of the evaluative metaphor and represents the typology of demographic, socio-cultural, and national-cultural signs of the evaluability of metaphors. The axiological status of the metaphor is established by a comprehensive description of the semantic, syntactic, pragmatic, and sociolinguistic features of the evaluation of the metaphor in modern English. The specificity of evaluativeness as a component of meaning in the semantics of a metaphor is determined. The results of the study of metaphor are presented in many linguistic works. However, some provisions concerning the functioning of the metaphor and its ability to reflect the individual author’s worldview have not yet been sufficiently studied. To study the metaphor as an assistant to the creation of images that express the author’s attitude to something and its social, political, philosophical position, and as a means by which we know the world around us, it is necessary to examine the existing theoretical material and subsequent analyses of specific cases of using the metaphor.
Linguistic innovation during the COVID-19 pandemic: the Spanish language case
Authors: Zholobova Anna
Published: May 2021

The paper contributes to the study of the impact that the COVID-19 pandemic has produced and is producing at the present moment on the Spanish language. The impact is, of course, reflected at the lexical level as many new words and expressions have been coined to designate segments of new extralinguistic reality generated by the pandemic and the “new normal”. The article analyses recent “pandemic” updates of the Spanish Royal Academy dictionary electronic version DLE 23.4 and “covidic” neologisms and occasionalisms from semantical and morphological points of view.
Estrategias y organización digital de los profesores universitarios en enseñanza y conectividad en el contexto de la pandemia generada por el COVID-19
Authors: Jiménez-Consuegra Mayra Alejandra , Flórez Maldonado Emma , Domenech Pantoja Geraldis , Berrio-Valbuena Jesús , Rodríguez-Nieto Camilo Andrés , Cervantes-Barraza Jonathan Alberto , Aroca Araújo Armando
Published: May 2021

El problema de investigación consistió en las implicaciones pedagógicas, didácticas, metodológicas y evaluativas emergentes del cambio repentino de educación presencial a la educación virtual en todos los programas de pregrado de la Universidad del Atlántico, sin que los docentes hayan recibido una formación previa. Por lo cual, el objetivo de esta investigación fue obtener elementos de discusión sobre estrategias didácticas, organización digital, procesos metodológicos y de evaluación de docentes de la Universidad del Atlántico, en el contexto de la pandemia producida por el COVID-19, durante el inicio del primer semestre virtual en cada una de las carreras profesionales. Este estudio es descriptivo, exploratorio y no experimental, llevado a cabo por el Grupo de Investigación Horizontes en Educación Matemática (GIHEM), donde la información se recolectó por medio de una encuesta en línea, diseñada en Google Forms y divulgada masivamente por medio de correos electrónicos de los profesores participantes. Entre los principales resultados, se destacan las estrategias que giran en torno a tres categorías: 1) disposición para las clases virtuales, 2) metodologías para el desarrollo de clases y 3) estrategias evaluativas en el proceso de enseñanza y aprendizaje virtual.
Percepciones de los estudiantes sobre la estrategia Aprende en Casa durante la pandemia COVID-19
Authors: Sosa Neira Edgar Andrés
Published: May 2021

Este estudio explora las percepciones de los estudiantes de básica secundaria y media sobre la estrategia Aprende en Casa implementada durante la pandemia (COVID-19) en el Área de Matemáticas del Colegio la Aurora IE, jornada mañana, ubicado en Bogotá-Colombia. Se utilizó un análisis de contenido inductivo cualitativo donde participaron 174 estudiantes y los datos fueron recolectados mediante una guía de aprendizaje. Las percepciones, tanto positivas como negativas, se agruparon en lo académico (guía autocontenida + TIC, competencias, procesos, actores e infraestructura), en lo social (cumplimiento de la norma, pensar en el otro, compartir en la familia, falta de socialización) y en lo personal (problemas de salud y actividades de tiempo libre). Los resultados permiten a los docentes reconfigurar su práctica para mejorar en los aspectos que influyeron en las percepciones negativas, y a las instituciones educativas empezar el camino de la transformación digital con el uso de las TIC para mejorar los procesos educativos.
La brecha digital como una nueva capa de vulnerabilidad que afecta el acceso a la educación en México
Authors: Villela Cortés Fabiola , Contreras Islas David Sebastián
Published: May 2021

La pandemia por COVID-19 provocó, entre otras cosas, la suspensión de clases presenciales. Con la campaña “Quédate en casa”, que oficialmente inició en México el 23 de marzo de 2020, las instituciones educativas se vieron en la necesidad de migrar sus servicios súbitamente al entorno digital. Sin embargo, la falta de acceso a Internet ha puesto en evidencia cómo el derecho humano a la educación, considerado como un derecho habilitante, se ve afectado desde nuevas dimensiones entre las cuales es indispensable considerar no solo el analfabetismo lectoescritor sino también el digital, así como la brecha digital desde los ámbitos de acceso, de uso y de competencia. Abordar estos dos aspectos desde su complejidad nos permite presentar la brecha digital como una capa de vulnerabilidad en cascada, que afecta no solo el derecho a la educación, sino que genera y detona otro tipo de vulnerabilidades pedagógicas. Consideramos que este análisis ensayístico puede servir para visibilizar aquellas áreas que requieren atención y permitirían tomar acciones positivas para reducir las capas de vulnerabilidad que devienen de la brecha digital.
Inositol and vitamin D may naturally protect human reproduction and women undergoing assisted reproduction from COVID-19 risk
Authors: Bezerra Espinola M.S. , Bertelli M. , Bizzarri M.
Published: May 2021

In late 2019, the new Coronavirus has been identified in the city of Wuhan (China) then COVID-19 spreads like wildfire in the rest of the world. Pregnant women represent a risk category for increased abortion rates and vertical transmission with adverse events on the newborns has been recently confirmed. The scientific world is struggling for finding an effective cure for counteracting symptomatology. Today, there are many therapeutic proposes but none of them can effectively counteract the infection. Moreover, many of these compounds show important side effects not justifying their use. Scientific literature reports an immune system over-reaction through interleukins- 6 activation. In this regard, the possibility to control the immune system represents a possible strategy for counteracting the onset of COVID-19 symptomatology. Vitamin D deficiency shows increased susceptibility to acute viral respiratory infections. Moreover, Vitamin D seems involved in host protection from different virus species by modulating activation and release of cytokines. Myo-inositol down-regulates the expression of IL-6 by phosphatidyl-inositol-3-kinase pathway. Furthermore, myo-inositol is the precursor of phospholipids in the surfactant and it is applied for inducing surfactant synthesis in infants for treating respiratory distress syndrome. This review aims to summarize the evidence about COVID-19 infection in pregnant women and to encourage the scientific community to investigate the use of Vitamin D and Myo-inositol which could represent a possible preventive treatment for pregnant women or women undergoing assisted reproductive technologies.
Pain syndrome in adenomyosis. Finding new pathogenesis links and non-hormonal correction opportunities. Literature review
Authors: Kalugina L.V. , Pavlova K.S.
Published: May 2021

Adenomyosis is characterized by polymorphism of clinical manifestations and is the cause of chronic pelvic pain associated with endometriosis in 53–80% of cases. Heavy dysmenorrhea in adenomyosis is a key factor that reduces the quality of life and, moreover chronic pain reduces stress resistance and launches the rehabilitation cytokines cascade, which causes exacerbation of endometriosis. Formation of painful syndrome with adenomyosis may be due to: changes in neurohumoral regulation, stimulation of nerves and blood vessels growth and myometrium inflammatory remodeling against the background of circulatory disorders and vascular sclerosis. These processes lead to violation of neuroimmune relationships that determine the increase in the number and sensitivity of nociceptors against the background of the chronic immuno-inflammatory process in endometrials and myometry.Experimental studies have shown that the supraspinal role of the nitric oxide (NO) is to indirect mechanical nociceptive reflexes. The dose-dependent L-arginine role in the pain syndrome formation also was shown; it was found that small doses of L-arginine lead to the activation of nNO-synthase and analgesic effect. Large doses are activated by cotorphine synthase to form a dipeptide of cortorphine (L-tyrosine-L-arginine), which induces the met-enkephalin release and analgesic effect. Individual studies have demonstrated a decrease in the symptoms of urinary pain syndrome during L-arginine treatment, which made it possible to include it into the European Association of Urologists recommendations on the chronic pelvic pain treatment in 2017.Clinical comparative study (2013) of the NO donator (L-arginine) effectiveness in the treatment of endometriosis-associated intermenstrual pelvic pain and dysmenorrhea showed a high efficiency of a 3-month course of combination therapy (dienogest 2 mg + Tivortin 4.2 g). Supplement of basic therapy by NO donator (L-аrginine) has shown a faster reaching the clinical effect on reducing endometriosis-associated symptoms and sustainable maintenance of the result achieved. The multifaceted pharmacological effects of L-arginine directly affect a number of essential factors for the adenomyosis development and progression, which allows using this drug in clinical practice.
Effectiveness of local application of antiseptic with octenidin dihydrochloride molecule in smoking women with ASC-US and LSIL
Authors: Akulina O.O.
Published: May 2021

This article presents the results of our own experience of topical use of the Prodexin antiseptic that is contained an octenidine dihydrochloride molecule as a monotherapy for ASC-US and LSIL cervical pathology (identified with in fluid cytology) associated with human papillomavirus in smoking women.Study objective: To study the efficacy of topical application of the octenidine dihydrochloride molecule in the Prodexin vaginal suppositories in the treatment of smoking women with ASC-US and LSIL.Materials and methods. The study involved 45 female smokers with identified ASC-US or LSIL. The complex of examination included: Pap test based on liquid cytology, testing for human papillomavirus 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68 types in a quantitative format, screening for the causes of vaginitis, extended colposcopy to exclude cervical intraepithelial neoplasia II+. Prodexin suppositories were used according to a 3-month treatment regimen (20 suppositories daily, and then 10 suppositories in two consecutive cycles).Results. Clinical and laboratory assessment of the therapy effectiveness has convincingly shown its positive effect on the vagina and cervix. Treatment with the Prodexin antiseptic associated with microbiota normalization, colposcopic picture improvement and changes in the Pap smear to NILM I or II. Regress to NILM was recorded in 20 (86.9%) patients with ASC-US and in 15 (68.8%) women with LSIL.Conclusions. Prodexin allows to avoid a worsening of the situation and prevent the changes progression in HSIL. Proposed treatment had no side effects, was convenient to use and did not require additional visits to doctor during therapy. The control over the human papillomavirus and study of the viral load has been postponed for 6–12 months from the beginning of the examination, that will be the second stage of work.
Characteristics of Language Behavior and Speech Activity in Children with Autistic Disorders: Theoretical Aspect
Authors: Bazyma Nataliia , Koropatova Oksana , Bondarenko Yuliia , Forostian Olga , Sokolova Hanna , Kovylina Veronika
Published: May 2021

Speech development of a child with autism does not always take place at the appropriate age and does not always obey the laws of development of speech functions. According to the analysis of literature sources, the direct study of speech activity of children with autistic disorders requires a more detailed study. According to our predictions, a child with autistic disorders of older preschool age due to the peculiarities of communicative and behavioral spheres will show a low level of speech activity, which can be explained directly by the specificity of speech development along with limited language experience and insufficient knowledge of language and its use in communication. Language behavior consists of two complementary and interrelated processes: psychological formation (generation) of speech utterance and perception of the expanded speech of the interlocutor. The model of speech utterance generation includes five consecutive, interconnected stages (phases) identified by O.O. Leontiev (1967): the motive of utterance; the idea of expression; internal programming; lexical and grammatical development of the utterance; implementation of speech expression in external speech. Speech activity is one of the many forms of general activity, a reflection of the needs that arise in accordance with specific communication situations, a prerequisite and an important component of language behavior. The term "speech activity" is considered by us in the sense of the presence of a motive for speech utterance and direct speech utterance, which may occur as a reaction-response to the interlocutor's remark or as a desire to inform the interlocutor of their own thoughts, experiences, emotions, needs.
Research on the Experience of Users of Political Slogans in Ukraine
Authors: Tkach Bohdan , Lytvynchuk Lesia , Popovych Ihor , Blynova Olena , Zahrai Larysa , Piletska Liybomyra
Published: May 2021

The study partly reveals “Zelenskyi’s phenomenon”, when a person without any political experience confidently won a victory over an experienced politician at the presidential and parliamentary elections. The paper considered neuropsychological understanding of a brand as a multi-modal image with emotional connection and as an artificial addiction. Specific features of the perception of political slogans were studied with EMOTIV Epoc+ 14-channel mobile neurointerface and EmotivPRO and EMOTIV Brain Activity Map software. The ranking of slogans in terms of the efficiency of perception of the individuals of 40-60 years old was carried out on the basis of EEG and the cognitive and emotional indexes: obtained stress, interaction, interest, excitement, concentration, relaxation. The study involved 30 men and 30 women who intended to vote in the presidential elections of 2019. It was established which slogans are the best, good, average, ambiguous, with little effect, ineffective, with a negative effect. It was determined that the most effective and at the same time efficient slogan that evokes emotions and really encourages to support is PRESIDENT IS PEOPLE’S SERVANT. The best slogan that appeals to support it is “We Are Ukraine”, “New Policy of Ukraine”, “Country of Strong People!” The basic cognitive and emotional indexes that would contribute to the creation of effective psychological impact on voters’ behavior are the presence in the slogan of the word “Ukraine”, the avoidance of the so-called “stop words” (for women it is “army” and everything related to violence and death, and for men it is everything related to the provision of material benefits), the use of religious sentimentality in women and gender differences in slogans targeting. The value of the studied phenomenon and the efficiency of slogans and other media products before launching them into mass advertising has been proved.
Augmented Reality Applications in Science Experiment Practices
Authors: Onbasi Duriye , Falyali Hanife , Ozdamli Fezile
Published: May 2021

The purpose of this paper is to explore the impact of augmented reality (AG) and the flipped learning model on the attitude of 4th-grade students towards the science and technology course and to determine the opinion of students concerning videos presented through AG. Another objective of the study is to determine parents' opinions concerning AG and FL in science and technology courses. A pre-test / post-test quasi-experimental design was used with the control group to obtain quantitative data. Qualitative data were also included in the analysis to support quantitative data obtained from a case study pattern. In the study, the Science and Technology Attitude Scale was used to measure students' attitudes. The Opinion Scale for Experimental Videos was used to evaluate video usage opinions in science and technology courses. Besides, parents' opinions concerning AG applications and the FL model were collected through the researchers' interview form. Independent sample t-test and ANCOVA tests were conducted to interpret the quantitative data of the study. Qualitative data were evaluated with the content analysis method. The results showed that the AR and FL model's application provides students with a positive attitude towards science and technology; it also helped them solve problems. Besides, families have also expressed positive opinions about AR and FL applications.
Psychological Peculiarities of Styles of Professional Activity and the Level of Stress among Members of Election Commissions in Parliamentary Elections in Ukraine
Authors: Lefterov Vasiliy , Ignatieva Iryna , Prykhodko Ihor , Timchenko Olexander , Formaniuk Yuliia , Holina Olha
Published: May 2021

The results of the empirical study among the members of election commissions (N=112, age: 25−68 years) for Ukrainian parliamentary elections 2019 to study the styles of their professional activity and the level of stress are presented. The most pronounced style of professional activity is “Professional-perfectionist”, which contributes to the high productivity of members of election commissions. The work tasks at a polling station are best fulfilled by the person with a more pronounced style of professional activity “Formalist-bureaucrat”. It is undesirable to involve working at the polling station persons with high rates in the style of the professional activity of “Nihilist”. It has been found that the major psychological difficulties of working in election commissions are due to excessive psycho-emotional and psychophysical overload, to which some members of the commissions are not ready. This overload can cause them to experience certain mental stress, different levels of stress, their manifestation, and consequences. Although the majority of participants demonstrated a high degree of adaptability to stressful workloads, members of commissions should perform their duties at a highly professional level in extremely difficult circumstances, including at night and in a state of intense emotional stress. The results of the research should be taken into account during the organization of the election process and the holding of elections to central and local authorities. To improve it, it is advisable to organize and conduct early training and skills upgrading of members of election commissions. To do this, it is necessary to develop and implement training programs for the development of style peculiarities of professional activity, which will contribute to effective work in the election commission and overcoming psychological difficulties.
Stanisława Grochowskiego Modlitwa Kazimierza ś[więtego], królewica polskiego, łacińskim rytmem przez tegoż świętego napisana i takimże na polskie przetłumaczona – dzieje i charakterystyka utworu, edycja krytyczna
Authors: Wichowa Maria
Published: May 2021

Ksiądz Stanisław Grochowski był wybitnym tłumaczem liryki religijnej. Dokonał przekładu z łaciny wszystkich hymnów kościelnych (Kraków 1598). Następnie w roku 1606 opublikował tłumaczenie fragmentu utworu Mariale Bernarda z Morlas (XII w.) czyli hymnu Omni die dic Mariae, w XVI wieku w Polsce uznawanego za dzieło św. Kazimierza. Było to wydanie bilingwiczne: tekst łaciński opracowany krytycznie przez Grochowskiego na podstawie dostępnych mu rękopiśmiennych przekazów i polski przekład poetycki tegoż autora wraz z nutami wybitnego kompozytora Diomedesa Catona. Edycja była pomyślana jako popularny śpiewnik przeznaczony do użytku wiernych Kościoła katolickiego, zaangażowanego w walce o rząd dusz z wyznaniami reformacyjnymi. Stanowiła dowód zaangażowania kapłana w walkę z kontrreformacją i ważny krok na drodze popularyzacji średniowiecznej modlitwy w renesansowej kulturze religijnej.
ОБОСНОВАНИЕ ТЕХНОЛОГИИ УЛЬТРАЗВУКОВОГО ВОЗДЕЙСТВИЯ ДЛЯ РАЗРУШЕНИЯ СТОЙКИХ ВОДОНЕФТЯНЫХ ЭМУЛЬСИЙ
Authors: Лекомцев Александр Викторович , Мордвинов Виктор Антонович , Дворецкас Ромас Вальдасович , Степаненко Иван Борисович , Баканеев Виталий Сергеевич , Силичев Максим Алексеевич , Корнилов Константин Витальевич
Published: May 2021

Актуальность. Подготовка продукции добывающих скважин до требований 1 группы качества товарной нефти в Пермском крае с каждым годом становится все более актуальным вопросом. Большинство эксплуатационных объектов находятся на завершающих стадиях разработки и характеризуются высокой обводненностью скважинной продукции, что в дальнейшем при сборе и промысловой подготовке приводит к образованию водонефтяных эмульсий. Стойкие водонефтяные эмульсии плохо подвергаются разрушению при подготовке их традиционными методами, такими как термическое и термохимическое гравитационное отстаивание. Данные методы подготовки просты в практическом применении, но не всегда обеспечивают требуемый результат. В связи с этим актуальной задачей является поиск и практическое применение новых технологий подготовки углеводородного сырья, которые могут применяться как отдельно от традиционных методов, так и в совокупности с ними. Таким методом является ультразвуковое воздействие. Цель: провести оценку эффективности ультразвукового воздействия при разрушении стойких водонефтяных эмульсий, подобрать оптимальные параметры ультразвукового воздействия. Объект: водонефтяная эмульсия с резервуара водоподготовки на установке промысловой подготовки нефти, которая расположена на территории Пермского края (Россия). Методы: определение основных технологических показателей эффективности ультразвукового воздействия, проведение опытно-промышленных испытаний, построение ключевых графиков и зависимостей. Результаты. Показан опыт применения ультразвукового воздействия, отмечена высокая эффективность разрушения стойких водонефтяных эмульсий по сравнению с традиционными методами. Авторами работы проведены опытно-промышленные испытания на мобильной установке подготовки скважинной продукции с применением ультразвукового воздействия на стойкие водонефтяные эмульсии, произведена оценка технологического эффекта и разработаны рекомендации по практическому применению предложенного комплексного метода. Научная новизна работы заключается в определении параметров эффективного процесса разрушения конкретного типа стойких водонефтяных эмульсий при совмещении термохимического и импульсного ультразвукового воздействия в докавитационном режиме. Установлена возможность снижения дозировки реагента-деэмульгатора в комбинации с ультразвуковым воздействием до 50 г/т. Показано снижение эффективности разрушения стойких водонефтяных эмульсий при комплексном воздействии на эмульсию низкой (менее 4 %) обводненности. Показано, что работа импульсной ультразвуковой системы на режиме работа–пауза 95/5 является оптимальной.
ПРИМЕНЕНИЕ СЕЙСМОФАЦИАЛЬНОГО АНАЛИЗА ДЛЯ ОЦЕНКИ ПЕРСПЕКТИВ СЛОЖНОПОСТРОЕННЫХ КАРБОНАТНЫХ КОЛЛЕКТОРОВ НА ПРИМЕРЕ НЕФТЯНОГО МЕСТОРОЖДЕНИЯ (ПО ДАННЫМ ГЕОФИЗИЧЕСКИХ ИССЛЕДОВАНИЙ СКВАЖИН)
Authors: Чучалина Кристина Юрьевна , Коровин Михаил Олегович
Published: May 2021

Актуальность исследования определена необходимостью минимизации неопределенностей геологической интерпретации благодаря применению различных классификационных алгоритмов в процессе обработки всего комплекса геолого-геофизических данных. Цель: прогноз и статистическое обоснование распределения фаций на основе геофизической информации на примере одного из месторождений Томской области. Объектом исследования являются палеозойские отложения юго-восточной части Западно-Сибирской плиты – коллекторы сложнопостроенных карбонатных толщ, где встречаются терригенные образования и карбонатные разности – известняк и доломит. Исходя из условий построения сейсмофациальной карты, было выбрано окно исследования, которое охватывает объем горной породы равный 40 м. Методы исследования основаны на применении классификационных алгоритмов к сейсмическому сигналу, которые разделяют исследуемый объект на однородные по ряду признаков области. В классификационный алгоритм по сейсмической трассе очень часто включают геофизические исследования скважин и лабораторные исследования керна, что подразумевает комплексирование информации. Комплексная интерпретация сейсмических и скважинных данных позволяет прогнозировать на качественном уровне литофациальную изменчивость на локальных участках, что способствует более рациональному размещению эксплуатационных скважин. В результате исследования выделены и ранжированы литотипы пород продуктивной толщи на основе сравнения сейсмического параметра – акустический импеданс, по данным скважинной и сейсмической информации. Сопоставление данных осуществлено с помощью восстановленных измерений плотностного каротажа. Предложенная схема комплексирования информации для перспектив нефтегазоносности палеозойских отложений на примере нефтяного месторождения Западной Сибири позволит выделить перспективные зоны для планирования бурения новых скважин.
Die Bittereindevrede van 31 Mei 1902: ‘n Hostories-etiese Perspektief
Authors: Strauss Pieter Johannes
Published: May 2021

Abstract: The die-hard peace of the 31st May 1902: a historical ethical perspective

The remainder of Boers fighting the last part of the Anglo-Boer War (1899-1902), are known as the die-hards. However, the characteristics of a die-hard or bitter end were not defined or uninamously recognized by the Boers. In the circumstances of April-May 1902 peace talks began and led to the signing of a peace treaty on 31 May 1902. In the development of the discussions among themselves a realisation was reached by the vast majority of the 60 Boer delegates that this was inevitably the end of the bitter end: the die-hard end.

This realisation is discussed within a Christian historical and ethical perspective.

Opsomming: Die bittereindervrede van 31 Mei 1902: ‘n histories-etiese perspektief

Die Bittereinderboere wat die Britte in die laaste deel van die Anglo-Boereoorlog (1899-1902) die stryd aangesê het, het nie ‘n konsensus gehad oor die aard van ‘n bittereinde nie. Onder die – vir hulle – moeilike omstandighede in die laaste fase van die oorlog het vredesamesprekings wat tot die onder tekening van ‘n vredesverdrag op 31 Mei 1902 sou lei, ‘n besef onder die 60 afgevaardigdes van die Boere geskep dat dit nou die einde van die bittereinde is.

Hierdie besef word binne ‘n Christelik-historiese en etiese perspektief bespreek.
APPLICATION OF MULTIPOTENT MESENCHYMAL STEM CELL SECRETOME IN THE TREATMENT OF ADJUVANT ARTHRITIS AND CONTACT-ALLERGIC DERMATITIS IN ANIMAL MODELS
Authors: Golubinskaya P. A. , Sarycheva M. V. , Dolzhikov A. A. , Bondarev V. P. , Stefanova M. S. , Soldatov V. O. , Nadezhdin S. V. , Korokin M. V. , Pokrovsky M. V. , Burda Yu. E.
Published: May 2021

The therapeutic effect of multipotent mesenchymal stem cells has been proven on various disease models. One of the mechanisms is the paracrine effect of the cells on the surrounding tissues.

The aim. To investigate the secretome effectiveness of the multipotent mesenchymal stem cells in the treatment of adjuvant arthritis and contact-allergic dermatitis in Wistar rats.

Materials and methods.Adjuvant arthritis was simulated in 26 female rats by the administration of Freund's complete adjuvant and then treated with the administration of 100 µl of multipotent mesenchymal stem cell secretome or saline. Contact-allergic dermatitis was modeled on 30 female rats by applying 200 μl of an oil solution of dinitrofluorobenzene to the skin on days 1, 5 and 6. Then the rats were treated with fluocinolone ointment (a positive control), baby cream (a negative control), baby cream with a secretome of native multipotent mesenchymal stem cells or from the cells processed with dexamethasone.

Results.Judging by the indicators of the longitudinal and transverse dimensions of the paws in rats and a histological examination, the secretome did not have any anti-inflammatory effect on adjuvant arthritis. A cream with a secret from multipotent mesenchymal stem cells processed with dexamethasone, was the most effective on the model of contact-allergic dermatitis: the clinical improvement occurred on the 2ndday. The secretome from native multipotent mesenchymal stem cells and fluocinolone had a therapeutic effect on the 3rdday of application, the negative control - on the 4thday. The lymphocytic infiltration coefficient was significantly lower (p <0.05) in all the cases compared to the negative control (2.8 ± 0.1). However, the lowest infiltration was observed when the cream with secretome from native (1.75 ± 0,1) and dexamethasone-stimulated (1.76 ± 0.1) multipotent mesenchymal stem cells was being used.

Conclusion.The cream with the secretome of multipotent mesenchymal stem cells suppresses lymphocytic infiltration more strongly than the highly active topical glucocorticosteroid - fluocinolone - on the model of contact-allergic dermatitis, which is a classic local delayed-type hypersensitivity reaction. However, a further study of the therapeutic effect of the secretome on models of systemic inflammatory diseases is required after its preliminary purification from large-molecular proteins.
STUDY OF PHARMACEUTICAL SPECIALISTS’ INFORMATION AWARENESS ON THE MATTERS OF DRUG ABUSE
Authors: Porseva N. Yu. , Soloninina A. V. , Dvorskaya O. N.
Published: May 2021

Prevention of non-medical use of drugs is the most important task of the state anti-drug policy of the Russian Federation, the effectiveness of which can largely be due to the professional awareness of pharmaceutical specialists, their compliance with the established regulations for the dispensing of drugs, and proper pharmaceutical advice.

The aim. The research of pharmaceutical specialists’ information awareness on the matters of drug abuse.

Material and methods. The study was based on the analysis of the regulatory legal acts of the Russian Federation governing the procedure for prescribing and dispensing drugs, instructions for the medical use of the drugs used for the purpose of abuse. In the course of the study, a systematic approach has been applied. It includes methods of structural-logical, cluster and content analyses, methods of generalization and grouping. The study of pharmaceutical specialists’ information awareness on the matters of drug abuse was carried out using a random sample survey using a specially developed questionnaire: 396 employees of pharmacy organizations of various forms of property from the Perm Territory, the Chelyabinsk and Kirov regions, the Udmurt and Chuvash Republics, the Komi Republic, were questioned in the period from 2017 to 2019. The questionnaire included 35 questions, structured in 4 blocks. The first block included questions on education, position, work experience of the respondents, the second - questions on identifying knowledge on the range of drugs used for abuse, and categories of consumers of such drugs. The third block contained questions on the regulation and compliance with the procedure for dispensing drugs. The fourth block of the questionnaire was intended to establish the methods and sources of obtaining information on the abuse of the drugs sold by specialists of pharmacy organizations.

Results. On the basis of the analysis carried out, an insufficient level of knowledge by specialists of the regulatory legal acts governing the trade of drugs, the range of drugs used for the purpose of abuse, and the categories of their consumers have been established. The violation of the rules for dispensing drugs has been revealed, as well as the lack of systematic sources of information on drug abuse.

Conclusion. The need to develop a training program for pharmaceutical specialists on the prophylaxis and prevention of drug abuse has been established. In order to work out additional competencies in the prevention of non-medical use of drugs and improve the quality of pharmaceutical consulting, it is necessary to conduct appropriate educational activities.
Czech bibliology in the twenty-first century — its historical development and current state
Authors: Šícha Vojtěch
Published: May 2021

The assessment of the current state of bibliology in Czechia, i.e. directions of its development and research accomplishments as well as staﬀ training, is impossible without a historical overview of the evolution of bibliology as a more or less independent scholarly discipline. A study has recently been devoted to the subject, but only for the period until the beginning of the Second World War. That is why the author of the article, drawing on the literature on the subject, internet sources and information obtained from the staﬀ of relevant research institutions, focuses ﬁrst of all on the second half of the twentieth century, i.e. the role and accomplishments of the most important ﬁgures involved in the development of the discipline, the position of bibliology in the higher education system at the time as well as the changes which occurred in it in connection with the political breakthrough of 1989 and the emergence of computerised systems towards the end of the twentieth century. A substantial part of the article is devoted to the events from the last two decades. The author notes the rather diﬃcult situation of the discipline at the turn of the millennium as well as attempts to rebuild it, manifested primarily in its restoration to the curriculum in the 2007/2008 academic year, increasingly successful eﬀ orts of libraries and museums (“institutions of memory”) to obtain funds for scholarly activities, and attempts to formulate a concept of further development of the discipline. In the conclusion the author reﬂ ects on the prospects for the development of bibliology in the nearest future, as well as measures that may lead to is further evolution and revival in broad research into the history of book culture in Czechia.
Jakub hr. Potocki i jego dar dla Biblioteki Publicznej m.st. Warszawy z 1934 roku
Authors: Pawlikowski Tomasz
Published: May 2021

The aim of this article is to present the little recognized, but meritorious person ﬁgure of J. Potocki and his family in historical context, as well as to characterize the gift given to the Warsaw Public Library. The biographical ﬁndings presented below, critical references to some information contained in modest studies, as well as the indication of certain facts related to the condition of the collection of books and its transfer to the Public Library, were based on reviewed archival materials, partially preserved old catalogues, 19th and 20th century press releases, literature on history and library science. The method used was mainly a comparative analysis of materials encountered in the course of queries, with a preference for sources.
Jakub Count Potocki (1863–1934) came from a well-known aristocratic family. He contributed to the Republic of Poland mainly through philanthropic activities. Shortly before his death, he was awarded the Great Ribbon of the Order of Polonia Restituta. Undoubtedly, his most important work was the bequest of almost all assets worth over 37 million PLN for the Jakub Count Potocki Foundation (September 1934), which was to ﬁnance research on cancer and tuberculosis by statute. In the same document, he donated paintings, tapestries, sculptures and furniture to the National Museum in Warsaw, and the book collection of about 11,900 volumes gathered in Helenów near Pruszków, to the Warsaw Public Library. As a whole, this collection, through provenance records and established information about its gradual accumulation by Stanisław and Jakub Potocki, as well as by the earlier owners of the book collections that joined it, proves the involvement of some representatives of the Polish intellectual elite of the 19th century in maintaining the memory of the former Polish Republic and thus maintaining the national spirit. The deliberate thematic selection is indicated by the nature of the literature collected by Sapieha, Potocki, Ignacy Count Łoś, Bentkowski, Jerzy Samuel Bandtkie or Jan Wincenty Stężyński Bandtkie, Kazimierz Stronczyński, Pruszyński. The analysis of the contents of this book collection leads to a closer acquaintance with the history of these ﬁgures, sometimes forgotten and meritorious for the Polish culture of the partition period.
Stan badań dziejów młyna papierniczego w Dusznikach-Zdroju
Authors: Szymczyk Maciej
Published: May 2021

The article is devoted to the evolution of interest in the paper mill in Duszniki-Zdrój for over two centuries. The paper mill was established before 1562, when the Kłodzko region was part of the Kingdom of Bohemia. The mill played an important economic and cultural role for nearly three centuries. It stopped its operations during the great economic crisis and in 1939 was sold to the city of Duszniki. After the Second World War and incorporation of Silesia with the Kłodzko region into Poland, the mill was o ﬃcially recognised as a historic building (listed in 1956) and in 1968 it was turned into the Museum of Papermaking. It 2011 the paper mill was granted the status of a Monument of History, which paved the way for it to be included in the UNESCO list.Interest in the history of the mill dates back to at least the second half of the eighteenth century. In 1789 a detailed history of the mill was published in Beyträge zur Beschreibung von Schlesien by F.A. Zimmermann and a lot of the information included in it at the time still remains relevant. During the following century interest in the history of the mill was shown by J. Kögler and W. Hohaus, and in the early twentieth century — by F. Hössle or B. Maiwald. After the Second World War the history of the mill was studied by many Polish historians, including K. Maleczyńska, M. Kutzner, M. Przyłecki, K. Sarnecki and W. Tomaszewska. The interest in the paper mill and its history has been boosted on an unprecedented scale over the recent decade, after eﬀ orts were launched to have the mill entered in the UNESCO list. The paper mill has been studied by e.g. R. Eysymontt, A. Fortuna-Marek, G. Grajewski, A. Kozieł, R. Sachs, A. Szeląg, B. Szmygin, as well as J. Bałchan and M. Szymczyk, both of whom were associated with the museum. In 2018 the Museum of Papermaking published a Monograph of the Duszniki-Zdrój Paper Mill, which contains the latest ﬁ ndings about the history of the paper mill and which will be used in the nomination for the mill to be included in the World Heritage List.
Manifestations of language awareness in the use of persuasive acts of speech in Middle Polish Sejm diaries
Authors: Dawidziak-Kładoczna Małgorzata
Published: May 2021

Persuasion as a rhetorical action is the basic indicator of parliamentary speech. Therefore, it seems reasonable to ask whether the diarists describing the course of Sejm proceedings were aware of the use of persuasive acts of speech by MPs. The material analysed — 24 lexemes referring to the verbal acts of the speakers — was extracted from a dozen or so Sejm diaries documenting the proceedings in the Middle Polish period. The research has proven that diarists use verba dicendi, which indicate the result of a verbal act (e.g. namawiać, zagrzewać, pobudzać, obmawiać, napominać and animować) or that they pay attention to the persuasion process itself (e.g. dowodzić, emundować się, perswadować, wywodzić, konwinkować, allegować, okazować and remonstrować). In addition, the following nouns are used: dowód, wywód, komparacyja, argument, perswazyja, konkluzyja and racyja. Diarists deliberately use a variety of lexis because they strive to name the verbal acts of the speakers as precisely as possible.