bluuebunny/crossref_metadata_2025 huggingface dataset:
疫情與倫理價值——兼評范瑞平教授的＜大疫當前: 訴諸儒家文明的倫理資源＞
Authors: LI Chenyang
Published: March 2021

LANGUAGE NOTE | Document text in Chinese; abstract in English only.While largely agreeing with Ruiping Fan, Chenyang Li makes three points regarding the handling of COVID-19. First, in addition to state capacity, social trust, and leadership, as identified by Francis Fukuyama, factors responsible for successful pandemic responses include the value of individual freedom upheld by citizens. A high level of individual freedom can make it difficult to implement strict measures even when they are objectively necessary. Second, a strong state can be effective in handling a pandemic, but without checks and balances it also runs the risk of leading a country into a major catastrophe. Third, Confucian ethics and other ethics can aid in coping with the pandemic. However, their efficacy is not unlimited, and ultimately, human survival overrides other concerns.DOWNLOAD HISTORY | This article has been downloaded 8 times in Digital Commons before migrating into this platform.
STUDY OF THE PHYSICAL STATE OF THE STUDENTS FROM MIDDLE EAST COUNTRIES
Authors: Dolgier Evdokiya , Fidirko Marina , Igor Moroz , Iryna Smoliakova
Published: March 2021

The article analyzes the problem of the modern ideas about the physiological mechanisms, which support the
health of foreign students in the organism-environment system in the conditions of study in institutions of higher education of Ukraine. The aim is to give a comparative characteristics of student's physical state from Middle East countries.
The male fourth-year students from Egypt and Israel have participated in the study. The authors carried out the analysis of special scientific and methodical literature, parameters of physical development and indicators of cardiovascular
and autonomic nervous systems, physical work capacity of the foreign students. The study has showed the predominance of
morphofunctional indicators of Israelis in comparison with students from Egypt in indicators of life index, strength
index of wrist and posture dynamometry, chest excursion. It is probable that most of students from Egypt (36,4%) had
overweight than students from Israel (8,3%). According to the Kerdoe’s Vegetative Index, ortho- and clinostatic tests,
which characterize the influence of sympathetic or parasympathetic divisions of autonomic regulation, the probable
(p ≤ 0,05) differences between the groups of subjects have been obtained, that allows to state that foreign students have
the imbalance in the autonomic regulation of body, so, to some extent, students in Israel have a tendency towards predominance of parasympathicotonic influences, while students from Egypt have a tendency towards predominance of sympathicotonic effects. The study of cardiovascular system types of physical activity and physical work capacity shows that
most of the foreign students had a normotensive type of reaction to physical exertion, high and above average level of
physical work capacity. According to the conducted study, a negative impact of the environment on the mechanisms of
autonomic support of the cardiovascular system was revealed, that requires some attention and timely adequate correction in order to prevent disorders of the nervous activity and the adaptive capacities of the students’ body in the analyzed
groups.
Analysis of Plankton Abundance and Status of Water Quality Fish Cultivation “Sawah Tambak” with Overtime System in Kalitengah Subdistrict, Lamongan Regency
Authors: Rahayu Agung Pamuji , Saad Moch , Fanni Norma Aprilia
Published: March 2021

The fish cultivation system in several villages in Kalitengah District uses an overtime system, namely a fish cultivation system that is carried out within 1 year (12 months) without passing rice planting. The research objective was to determine the abundance of plankton and the status of water quality fish cultivation “sawah tambak” with overtime system in Kalitengah District Lamongan. This is a quantitative research using descriptive methods. Based on the plankton abundance value at Station 1,2 and 3, the waters in the overtime system of ponds are in the Eutrooph category, with the abundance value > 12,000 Ind / L. Meanwhile station 4,5, and 6 are included in the Oligotrooph category since its abundance <10,000 Ind / L. The diversity value is within the range of 0.714267-1.823 which include in the category of small diversity and low community stability because the value of 0 <H '<1.5. All stations are in a moderate level of pollution which the diversity index value is within the range of 1 <H '<3. The Dominance Index (D) is in the range 0.212-1.224, Station 1 has a high dominance value because of the dominant species, namely Batrachospermum. Water quality parameters at all stations such asthe temperature ranges between 28.8-34.2 0C; the pH 8.5-9.2; Dissolved oxygen  4-10.44 mg / l; ammonia 0.009-0.17 mg / l; phosphate ranges from 0.025-2.3 mg / l. From the measurement results, water quality parameters show a good value for the growth of aquatic organisms.
Kadar Alanin Aminotransferase, Aspartat Aminotransferase dan Gambaran Histologi Hati Tikus Putih yang diberikan Ekstrak Kulit Pisang Kepok dan Latihan Intensif
Authors: Prasetyawan Putu Angga , Suarsana I Nyoman , Kendran Anak Sagung
Published: March 2021

Aktivitas tubuh seperti latihan yang intensif berlebih menyebabkan tubuh membutuhkan oksigen sangat banyak, sehingga memicu timbulnya radikal bebas yang dapat merusak berbagai organ salah satunya hati. Guna mencegah kerusakan sel-sel hati akibat radikal bebas, diperlukan usaha-usaha untuk memberikan asupan antioksidan dari luar. Salah satunya adalah kulit pisang kepok.  Penelitian dilakukan untuk mengetahui perubahan kadar Alanin Aminotransferase (ALT), Aspartat Aminotransferase (AST) serta gambaran histologi hati tikus putih yang diberikan ekstrak kulit pisang kepok serta latihan fisik intensif. Penggunakan 27 ekor tikus yang terbagi atas 3 kelompok, perlakuan diberikan selama 28 hari. Sampel darah dan organ hati diambil pada hari ke-29. Sampel darah diuji menggunakan metode fotometrik sedangkan sampel hati diperiksa melalui preparat histologi dengan metode pewarnaan hematoksilin eosin (HE).  Data hasil penelitian diuji menggunakan sidik ragam (ANOVA) dan dilanjutkan dengan uji Duncan. Hasil penelitian menunjukan pemberian ekstrak kulit pisang kepok pada tikus putih yang diberikan latihan intensif renang berpengaruh nyata dapat menurunkan kadar ALT, AST, dan dapat mengurangi terjadinya degenerasi dan nekrosis hati. Hasil penelitian dapat disimpulkan bahwa ekstrak kulit pisang kepok dapat mencegah kerusakan hati akibat  latihan fisik intensif.
GAMELAN SELONDING CHRICAL FUNCTIONS IN TENGANAN PEGRINGSINGAN VILLAGE
Authors: Suharta I Wayan , Suarka I Nyoman , Cika I Wayan , Setiawan I Ketut
Published: March 2021

This paper aims to study and understand the sacredness of the Salonding gamelan in Tenganan Village in its context with religious rituals and the people of Tenganan Village as protection. Gamelan Selonding in Tenganan Village has its own history, its existence is associated with stories or myths that have been passed down from generation to generation. The approach used is semiotic through interpretive analysis of texts and contexts that support the culture concerned. The research found that, starting with the discovery of three iron plate blades which were declared as Selonding gamelan blades. Believed to be a descent that is not made by ordinary humans, but because of the gift of nature, the people of Tenganan Village are called 'Bhatara Bagus Selonding'. Gamelan Selonding for the people of Tenganan Village is very sacred. In maintaining its sacredness it is adjusted to the concept of the village, kala, and patra, not to be touched by other people, except by members of the selected art group (Gambe) with seven members. Gambel juru has the responsibility to maintain the sanctity of the Selonding gamelan. For the people of Tenganan Village, the sacredness of the Selonding gamelan is not just an outward statement, but a totality that represents the integration of people's thoughts, feelings, speech and attitudes, so that the treatment of Selonding is prostration. So, Selonding for the people of Tenganan village, is not just a medium of artistic expression but a representation of religiosity so that selonding is sacred and sanctified. 

Keywords: Gamelan Selonding, representation, art, religiosity
Penerapan dan Evaluasi PSAP Nomor 13 dalam Penyajian Laporan Keuangan (Studi pada Universitas Pendidikan Ganesha)
Authors: Intan Kesuma Dewi A.A. Sagung , Muliartha Ketut
Published: March 2021

This research was conducted with the aim of knowing and evaluating the application of PSAP Number 13 in presenting the financial statements of Universitas Pendidikan Ganesha. This research uses qualitative methods with the approach used is a case study approach. Data obtained through documentation, observation, and in-depth interviews. The results in this study indicate that Universitas Pendidikan Ganesha has referred to PSAP Number 13. There are several obstacles found in the preparation of the financial statements which are, 1) the understanding of human resources in the use of the accrual basis is not yet comprehensive 2)  the  used  of  decentralized  system  in  financial management creates an biased information.

Keywords: PSAP Number 13; Financial Reports;  Public Service Agency.
Pendidikan, Lingkungan Keluarga dan Penggunaan Instagram terhadap Minat Berwirausaha Mahasiswa
Authors: Suarningsih Ni Luh Ayu , Rasmini Ni Ketut
Published: March 2021

This study aims to obtain empirical evidence of the effect of accounting education, entrepreneurship education, family environment and the use of Instagram on entrepreneurial interest in undergraduate accounting students of FEB Unud. The analysis technique used is multiple linear regression analysis techniques with the method of determining the sample using purposive sampling. Data collection was done by distributing questionnaires. The sample in the study were 257 respondents. The results of this study indicate that accounting education and entrepreneurship education have a positive and insignificant effect, while the family environment and use of Instagram have a significant positive effect on the interest in entrepreneurship in the undergraduate accounting study program of FEB Unud.

Keywords: Education; Family Environment; Instagram; Entrepreneurial.
Kejelasan Sasaran Anggaran, Sistem Pelaporan dan Kompetensi Perangkat Desa pada Akuntabilitas Pengelolaan Dana Desa
Authors: Sawitri Putu Ika , Gayatri Gayatri
Published: March 2021

The purpose of this study was to determine the effect of clarity on budget targets, reporting systems and the competence in  accountability of village fund management. This research was conducted on 27 villages in Denpasar City.  Respondents in this study was 135 people with a purposive sampling method. Data collection was carried out using a questionnaire. The analysis technique used is multiple linear regression. Based on the research results, it shows that the clarity of budget targets, the reporting system and the competence of village officials have a positive and significant effect on the accountability of village fund management.

Keywords: Budget; Reporting; Competence; Accountability.
Khazanah Leksikon Tradisi Penangkapan Ikan Paus dalam Novel Suara Samudra Karya Maria Matildis Banda: Kajian Ekolinguistik
Authors: Widarsini Ni Putu N.
Published: March 2021

This paper aims to find and analyze the forms and categories lexicon of the whale chathing tradition in the Suara Samudra novel by Maria Matildis Banda. To realize this, the library method and scrutinize method were applied in the data collection assisted with notes technical. And then, the data analyzed with qualitative description method and ecolinguistics theory. Then, the result showed with informal and formal method. The result showed that forms and categories lexicon of  the whale  chathing tradition in the Suara Samudra novel by Maria Matildis Banda writed with lexicon of Lamalera language. That the lexicon consist (1) biotic lexicon, like koteklema ‘whale’, lamafa ‘stab fisherman of whale’, and matros ‘paddle fisherman of boat’; and (2) abiotic lexicon, like peledang ‘boat’, kerakki ‘special chair of stab fisherman of whale in the boat’, and blettu ‘traditional hat from palm leaves’. The form of lexicon consist (1) singular form, like buri ‘trumpet from skin of shell’ and kela ‘place of ball of twine yarn’; (2) complex form, like lama uri ‘special fisherman for drive boat’ and tena laja ‘sailing boat’. The cathegory of lexicon consist noun and noun phrase.
Semiotics Approach on Verbal Signs in Would You Care More IF I Was A Panda?
Authors: Wishnawa Anak Agung Gede Hari , Sudipa I Nengah , Sukarini Ni Wayan
Published: March 2021

This study is aimed at identifying the verbal signs with their mode and connotative meaning of an advertisement. The data of this study was a wildlife advertisement entitled Would You Care More IF I Was A Panda? (2011) created by Ogilvy and published by World Wild Life. The data were collected using documentation method with note-taking technique. The data were analyzed qualitatively using Peirce’s semiotic theory to identify the verbal signs with their mode and Leech meaning theory to analyze the connotative meaning of the sign. The result of this study shown that there were three verbal signs found in the advertisements that belong to symbolic signs in the form of the combination of alphabets. The verbal signs consist of representamen, interpretant, and object. The connotative meanings are expressed in words, phrases, or sentences with the interpretation based on knowledge, emotion, and imagination.
Konteks Pembentuk Wacana Pacifism dalam Anime Hotaru no Haka karya Isao Takahata
Authors: Dana Pande Krisna , Ari Sulatri Ni Luh Putu , Anggraeny Renny
Published: March 2021

The tittle of this research was “Forming Context of Pacifism  Discourse in Hotaru no Haka anime by Isao Takahata”. The purpose of this research to find out the forming context of pacifism discourse in Hotaru no Haka anime by Isao Takahata. Data colletion method in this research was literature study method.   The data were analyzed by using descriptive analysis method and informal method. The theory applied in this research was critical discourse analysis by Van Dijk (1988). The result in this research were 1) novelist and anime director are victims of war; 2) prohibition of war in article 9 of the Japanese Constitution and; 3) Japan signed the treaty of San Francisco.
Perfil epidemiológico das doenças causadas pelo Aedes aegypti nos Distritos Sanitários de São Luís - MA
Authors: Dos Santos Eliane Coelho Rodrigues , Cohen Simone Cynamon , Costa Renato da Gama-Rosa
Published: March 2021

Objetivos: Descrever as características epidemiológicas dos Distritos Sanitários de São Luís - Maranhão, com enfoque nas três doenças transmitidas pelo Aedes aegypti: dengue, zika e chikungunya. Métodos: Estudo, de caráter observacional, descritivo, retrospectivo, seccional, se baseia na observação dos dados registrados pelo Sistema de Informações de Agravos e Notificação (SINAN), fornecidos pela Secretária Municipal de Saúde de São Luis (SEMUS). Resultados: No ano de 2011, houve uma maior notificação da dengue, sendo 5.378 casos. O gênero feminino predominou e a faixa etária com o maior número de notificações foi 20 a 39 anos. As notificações do zika vírus e chikungunya se iniciaram em 2015 com pico epidêmico em 2016. O Distrito Sanitário Bequimão o segundo mais populoso, notificou maior número de casos. Conclusão: A prevalência das doenças causadas pelo Aedes aegypti apresenta nas três arboviroses, variação endêmica relacionada ao adensamento populacional e às condições sanitárias locais, que, neste artigo, privilegiará o estudo da capital maranhense, em que se registra carência de infraestrutura sanitária e de abastecimento de água, merecendo a atenção das autoridades sanitárias e atuação permanente da população.
Síndrome de burnout: fatores sociodemográficos e ocupacionais em profissionais da enfermagem
Authors: Barbosa Italo Everton Bezerra , Fonseca Alicia Ribeiro , De Andrade Emmanuele Neuza Moreira , Maklouf Dandara Conceição , Ribeiro Meire Cristina Soares , Rodrigues Antônio José Paulo da Silva , Mota Breno de Souza , Laborda Yasmin Tainá Corrêa , Da Silva Vitória Diniz Bezerra Lúcio , Lira Felipe Chrystian de Figueiredo
Published: March 2021

Objetivo: Avaliar a incidência da Síndrome de Burnout (SB) em enfermeiros, auxiliares e técnicos de enfermagem, visando determinar variáveis sociodemográficas e ocupacionais, a fim de proporcionar elementos para uma compreensão mais aprofundada da SB nesses profissionais. Métodos: Trata-se de uma pesquisa do tipo descritiva, com abordagem qualitativa, utilizando a revisão integrativa de literatura (RIL) como técnica. O levantamento de dados foi realizado entre os meses de outubro de 2020 e janeiro de 2021, no banco de dados da Scientific Electronic Library Online (SCIELO) e Biblioteca Virtual em Saúde (BVS), utilizando os descritores em saúde: “Síndrome de Burnout AND Profissionais da Saúde AND Enfermagem AND Trabalho”, sendo encontrados 133 publicações na totalidade, após a aplicação dos critérios de elegibilidade e inelegibilidade, foram considerados 11 artigos para compor esse estudo. Resultados: A prevalência da SB em profissionais de enfermagem ainda e bastante significativa, com maior incidência nos auxiliares de enfermagem (52,94%), estando relacionado principalmente com a sobrecarga de trabalho. Considerações finais: Logo, torna-se perceptível a necessidade de as organizações lidarem com o estado de saúde dos funcionários, particularmente aquelas com maior proximidade físico-psicológica com o paciente/familiares, para que a SB possa ser prevenida.
Case of Shiitake Mushroom Dermatitis in a 21-year-old Female
Authors: Hill Sheena , Honda Kord , Rohr Bethany
Published: March 2021

Abstract not available.
Clinical and Histological Spectrum of Primary Cutaneous B-Cell Lymphoma in an Ethnically-Diverse Group of Patients: A Case Series
Authors: Farooq Sahira , Frizzell Madeline , Limmer Emily , Swali Ritu , Tyring Stephen
Published: March 2021

Primary cutaneous lymphomas, which are diagnosed with only skin involvement, can be of B or T cell origin. Due to their varied origin as well as their diverse presentations, these groups have been divided further into more descriptive and representative groups. The subtypes are primary cutaneous marginal zone lymphoma (PCMZL), primary cutaneous follicle center lymphoma (PCFCL), primary cutaneous diffuse large B cell lymphoma, leg type (PCDLBCL-LT) and intravascular large B-cell lymphoma. Here, we present the cases of three ethnically diverse patients with distinct clinical and histological forms of cutaneous B cell lymphoma.
Limitations on the simulation of non-sparse Hamiltonians
Authors: Childs A.M. , Kothari R.
Published: March 2021

The problem of simulating sparse Hamiltonians on quantum computers is well studied. The evolution of a sparse $N \times N$ Hamiltonian $H$ for time $t$ can be simulated using $\O(\norm{Ht} \poly(\log N))$ operations, which is essentially optimal due to a no--fast-forwarding theorem. Here, we consider non-sparse Hamiltonians and show significant limitations on their simulation. We generalize the no--fast-forwarding theorem to dense Hamiltonians, ruling out generic simulations taking time $\o(\norm{Ht})$, even though $\norm{H}$ is not a unique measure of the size of a dense Hamiltonian $H$. We also present a stronger limitation ruling out the possibility of generic simulations taking time $\poly(\norm{Ht},\log N)$, showing that known simulations based on discrete-time quantum walk cannot be dramatically improved in general. On the positive side, we show that some non-sparse Hamiltonians can be simulated efficiently, such as those with graphs of small arboricity.
Combating pandemics in India – A comparison study between the 1918, 2009 and 2019-2020 pandemics
Authors: Srinidhi Chandramoulie  , Balaji Ramraj  , Aarthy Marimuthu
Published: March 2021

Out of the many pandemics and epidemics that India has gone through in the last two centuries, two pandemics have been chosen-the 1918 Influenza pandemic and the 2009 H1N1 pandemic, to be compared with the current state of affairs with the Covid-19 pandemic. Critical review and analysis of pandemic preparedness and India’s response to the three pandemics was made through PubMed cited articles, exclusive reports from the Government in 1918, and authentic news coverage of the Covid-19 pandemic in line of healthcare, logistics and communication. Increase in healthcare facilities, laboratory services and research capacities noted through the three pandemics. Better surveillance methods and improved awareness of the public observed over the years. The readiness of the country for emergency measures with some inequalities discussed. Three different pandemics have been compared with an adequate interval between them barring the factor of healthcare inequity and virulence of the respective organism. It should be noted that there is no single solution for combating pandemics. Combined measures put together can help towards facing them with ease the next time around.
Lockdown: A Solution for Covid-19 Pandemic in India
Authors: Shlok Jaiswal
Published: March 2021

Novel coronavirus member of SARS (Severe Acute Respiratory Syndrome) known as Covid-19 which reported is first case in Wuhan city of china has spread worldwide and has become a pandemic of 21st century. But to stop its spread is lockdown a solution in INDIA or WORLDWIDE? To stop the spread of covid-19 in India lockdown was imposed in India from 24th March 2020 to 14th April 2020 of 21 days. Lockdown in INDIA was in Phase wise manner and was in 4 phases. PM announced first lockdown on 23rd of march after the JANTA CURFEW on 22nd march. Lockdown was beneficial for INDIA to a much extent because if lockdown would not have happened; in initial days it could have spread to a lot of people and it would have been challenging to state as well as central government to deal with this problem of Soo many people affected by covid because INDIA is not much developed in terms of health infrastructure. Though there was a lockdown and still cases were rising in India in an exponential manner, but lockdown gave some time to central as well as state government so that they can build isolation wards and can strengthen the health infrastructure of our country.
Mental Effect of Covid-19 Pandemic on Affected, Non Affected and Families of the Affected
Authors: Arpit Gupta
Published: March 2021

The pandemic of covid 19, which has taken the entire world by storm has not only tested our physical health but also impacted our mental health in ways no one had envisaged! It has lead to a situation of socioeconomic crisis and mental anguish among the general population. The outbreak of a novel virus unknown to the medical fraternity and its explosive spread every day, conflicting messages from the government, lack of infrastructure for treatment, the spread of misinformation on media platforms and an incessant quarantine has to lead to a sense of fear, apprehension, stress, desolation, weariness, frustration and depression among the masses. The imposition of lockdown in the nation not only undermined personal freedom, but it also leads to huge financial losses, unemployment, work and school closure, uncertainty, boredom, stigma which have been major stressors leading to widespread emotional affliction and an increased risk of developing psychiatric illness during the time of the pandemic. People who were already suffering from some form of the psychiatric disorder have been prone to exacerbations due to the pandemic. Individuals living with confirmed or suspected covid 19 cases, frontline workers, unemployed people and people in quarantine are at a higher risk of developing some form of mental illness such as anxiety, insomnia and depression. Resilience and good social support are protective factors against this mental health epidemic that is about to begin. In this article, we reflect upon the impact of covid 19 pandemic and lockdown on the mental health of people in India.
Positive Effects of COVID-19 Pandemic on Environment
Authors: Rashi Parashar
Published: March 2021

Under the agony of this recent pandemic going on, in the world due to Covid-19; there has been loss of millions of human lives along with huge economical shock and great recession through out the globe. Environmental degradation has been one of the biggest threats of this century. In spite of all the steps taken by environmentalists and government for the healing of environment in past few years, we couldn’t reach upto the mark. But during the lockdown, which was forced as a precautionary measure for Covid-19 pandemic, environment has successfully recovered to a large extent which was otherwise not possible. This has definitely brought a positive change in climate globally. This review article deals with various such positive impacts of lockdown on ecosystem. Covid-19 outbreak has restricted the social freedom of people globally. It has caused both positive and negative effects on environment. Reduction in greenhouse gas emission because of reduced transport facilities and industrial and other activities were some of positive effects of lockdown while negative effects on mental health of people and increased medical waste during the lockdown were some of the negative effects of lockdown. In this study, the relationship between Covid-19 outbreak and effects on environment was discussed in worldwide sense and a detailed review was conducted that could be used for further planning of researches on the same subject.
Correlation of Patient Satisfaction with Treatment Duration in Tooth Supported Full Mouth Rehabilitation Cases: A Retrospective Study
Authors: Rupawat Divya  , Vinay Sivaswamy  , Subhashree R
Published: March 2021

Full mouth rehabilitation is a comprehensive treatment and hence requires a longer duration along with patient co-operation and operator skill. Data of 86000 patients between June 2019 and March 2020 was reviewed from the patient's records and analysed that was documented in Saveetha Dental College and Hospital, Chennai, India. 152 patients who underwent tooth supported full mouth rehabilitation were included in this retrospective study. The data regarding the duration of the entire treatment, patient satisfaction, type of temporary teeth and change in vertical dimension was collected from Dental Information Archiving Software (DIAS). The data censored was collected by recalling the patient and reviewing. Statistical analysis was performed using pearson's correlation and chi square test to assess the association between patient satisfaction and increase in the vertical dimension, type of temporisation and duration of the treatment. The associations between patient satisfaction and increase in vertical dimension (Chi-square value : 8.809, df: 6, p value : 0.185), type of temporisation (Chi-square value : 8.809, df: 6, p value : 0.185) and duration of the treatment (Chi-square value : 303.548, df: 306, p value : 0.529) were statistically insignificant (p>0.05). From the available data it was observed the duration of the treatment plays a secondary role in relation to patient satisfaction in the treatment of full mouth rehabilitation cases. The quality of treatment and decisiveness in providing definitive care with respect to treatment needs gives better patient satisfaction.
Tazemetostat– A Drug review
Authors: Anju K Paul  , Hridya Jayamohanan  , Keechilat Pavithran
Published: March 2021

Epithelioid sarcoma affects three in 10 million people, usually teenagers and young adults. Tumours grow under the skin of the extremities or they can affect the trunk, head, or neck. It grows slowly, but can infiltrate surrounding tissues, later on, it frequently metastasis to lymph nodes. For advanced case, doxorubicin-based chemotherapy regimen is recommended. In January 2020, FDA approved the first-in-class, small molecule enhancer of zeste homolog 2 (EZH2) inhibitor, tazemetostat (Tazverik) to treat adults and paediatric patients aged 16 years and older with locally advanced or metastatic epithelioid sarcoma not suitable for complete resection. The recommended dosage is 800 mg twice daily until disease progression or unacceptable toxicity.  The first-in-human study of tazemetostat was a phase 1 open-label multi-centered dose-escalation study. Tazemetostat is having an oral bioavailability of approximately 33%. Apparent volume of distribution at steady-state (Vss/F) is 1230 L (46%) with 88% bound to human plasma proteins. Metabolism takes place via CYP3A. 15% and 79% of radioactivity is excreted through urine and feces respectively. ≥20% of the adverse reactions and above was fatigue, pain, constipation, nausea, anorexia and vomiting. This article summarizes the history, chemistry, physical properties, mechanism of action, indications, and drug–drug interactions of tazemetostat and we also discuss briefly the results of various clinical trials.
KEGUNAAN GINKGO BILOBA UNTUK PENGOBATAN PENYAKIT NEUROLOGIS
Authors: Sarifuddin Muftia Jauristika , Annisa Nurul
Published: March 2021

Ginkgo Biloba adalah Salah satu tanaman yang tergolong sebagai fitofarmaka atau obat-obatan yang berasal dari tanaman ialah Ginkgo biloba Tanaman G.biloba (Gb) termasuk dalam familia Ginkgoceae. Di dalam ekstrak G.biloba terdapat antioksidan, antivirus, antiinflamasi, dan juga antikarsinogenik. Dan juga telah dinyatakan bahwa ekstrak G.biloba mempunyai efek yang baik terhadap fungsi SSP (sistem saraf pusat). Untuk mengetahui manfaat G.biloba dalam penanganan gangguan neurologis. Dibuat dengan menggunakan metode studi pustaka untuk mengumpulkan referensi yang valid mengenai tanaman Ginkgo Biloba yang dapat digunakan sebagai penanganan gangguan Neurologi. Hasil literature review berdasarkan studi pustaka yang dilakukan menunujukkan bahwa tanaman Ginkgo Biloba yang dapat digunakan sebagai penanganan penyakit neuorologis dengan kandungan dan efek terhadap tubuh. Dalam literature review ini didapatkan tanaman  Ginkgo Biloba yang dapat digunakan sebagai penanganan gangguan neurologis
COLORS IN GOND TRIBAL ART: AN INTERPRETATION AND CRITICAL EVALUATION OF COLORS IN GOND PAINTINGS OF MADHYA PRADESH.
Authors: Bharadwaj Kumkum , Ukande Anu
Published: March 2021

Fork-art forms have the great social mission of creating cultural identity. The integrity of individuals and equipping them to meet social challenges are a part of this. In Madhya Pradesh- the heart of India lies the oldest found art heritage in the world. Gond Tribal paintings ofMadhya Pradesh have gained worldwide recognition in recent years. The Gond tribe, one of the largest Tribal communities of central India resides in Madhya Pradesh and Chhattisgarh. Over the past decades it has been observed that tribal people are being assimilated with the rest of the population and this process has been a continuous one. With the process of integration arise challenges of retaining, preserving and promoting the cultural elements of the tribes which may face the threat of extinction. This paper attempts to analyze the changes in Gond art brought about by their gradual assimilation into mainstream arts, and the future approaches to colors.
FORECASTING OF COLOURS IN CREATIVE COMPOSITION OF TEXTILE FABRIC AND FASHION
Authors: Ghosh Reeta
Published: March 2021

Colour is the most enriched and endless form of human life. It reflects our mood and more importantly, it has more influence and effect on our lives than we realize. How can we define colour, a reality, a feeling that creates energy, enthusiasm, potential, anger, affection, passion andmany other feelings in us. If we are in pleasant feeling, colour fills us with the feel of joy and happiness and in contrary to this if we are unhappy and sad the colours are there, who fill with the feel of unhealthy, unhappiness and sadness. Now it is a matter to think upon that why we correlate our feelings with colour or how colour reflects our mood or our internal expressions in a physical manner. It is not only because of colour but of course because of its composition too. We always look for a new colour palette range or a new invention but have we ever thought that from where did colours come and why they show their impact on us and our lives. Craving for colour, forces human to create invent and generate inventions, of course a human with artistic or creative brain and heart, who not only evolve in engraving of colours but also put efforts in to it to foster.
Assessing Accumulation of Organic Material on Rodent Cage Accessories
Authors: Allen Kenneth P , Csida Tarrant J , Thulin Joseph D
Published: March 2021

According to the 8th edition of the Guide for the Care and Use of Laboratory Animals (the Guide), rodent cage accessories, such as filter tops, should be sanitized at least once every 2 wk. We performed a study to test the hypothesis that organic contamination (measured by ATP content,
expressed as relative light units (RLU)) of cage accessories (wire bar inserts and filter top lids) does not differ at 2 wk (14 d) as compared with 30, 60, and 90-d time points after cage change even when in constant use. An additional time point for filter top lids of 180 d after cage change
was also evaluated. Eight groups were studied: the wire bar inserts and filter top lids used for mice and rats, in both static and individually ventilated cages (IVC). When analyzing data from both mouse and rat static and IVC caging, we found that the mean RLU values for mouse IVC and rat
static and IVC cage components were below 100,000 RLU at the 14-d time point. The mean value for the mouse static group was slightly above 100,000 RLU at this time point. Based on this observation, we considered 100,000 RLU to be an appropriate actionable level. We concluded that changing
wire bar inserts at least every 14 d, as recommended in the Guide for sanitizing these components in mouse and rat static cages, may be considered acceptable. This interval could be extended for mouse and rat IVC cages up to 90 d while remaining below this limit. Filter top lids for mouse
static cages should be changed at least every 30 d, but static rat and IVC mouse/rat filter top lids could be changed up to every 180 d, while still staying below this actionable level of contamination.
COVID 19 MEDIA COVERAGE: AN ANALYSIS OF HEORHII POCHEPTSOV’S VIEW
Authors: Levantovych Oksana
Published: March 2021

The article analyses the peculiarities of the coverage of the covid pandemic in the Ukrainian media, the emphasis placed by the media in news, and how the online mode of modern life and social distancing affects the growth of media influence. Special attention is paid to the view of the famous publicist Heorhii Pocheptsov, who does not exclude the possibility that the coronavirus was invented intentionally to control millions of people around the world. Permanently, the world faces numerous challenges of different scales: economic, military, socio-political, environmental, epidemiological ones. In 2020, the largest and the most unexpected event, undoubtedly, was the deadly coronavirus pandemic, which spread from the small Chinese province of Wuhan to the whole world and already took more than one million people’s lives in less than a year. Thus, the media, that in the post-information society actually have an unprecedented impact on people, form a person’s perception of such challenges. As a result, our understanding of the pandemic is directly related to the information we consume from the media. In fact, from the very start of quarantine, the media space began to be captured by analytical materials in which experts from various fields tried to predict what the world would be like after the end of coronavirus. These experts were of two types: some claimed that irreversible changes would deepen the permanent economic and socio-political crisis, and by claiming that they intensified panic, while others argued that any crisis is a chance to restart and grow. The experts put different emphases covering the covid pandemic in the media, but it is important to pay attention to the analysis of the famous publicist, propaganda researcher – Heorhii Pocheptsov, who sees the coronavirus as a tool to influence millions of people. The pandemic will end sooner or later, but no matter whether the virus was artificially invented or not, the processes that have already been launched around the world cannot stop as if nothing had happened. But Heorhii Pocheptsov’s opinion about the possible artificial nature of the virus should make us more vigilant while consuming information from TVs or from the online media, as it is possible that this information might be a part of a great game that we were not warned about.
IMPROVING THE QUALITY OF FUNCTIONING TECHNICAL SUPPORT MODULES OF IT- INFRASTRUCTURE
Authors: Kulagin Alexey , Feofanov Aleksandr
Published: March 2021

Currently, information systems are used in all fields of the human society. The main criterion for the optimal operation of an enterprise information system is complete automation. This is especially important when you need to handle huge data streams. In this regard, implementing automated control systems is extremely necessary. They significantly increase efficiency in all the areas of production and improve employees' productivity. In this case, it is necessary to pay special attention not only to creating some unified information environment, but also to the possibility of assessing the workload and functionality of its individual components. Such an opportunity is provided by applying the foundations of constructing the subsystem functional models.
Analisis Jurnal Ilmiah
Authors: Mahulete Ebenhaezer Yohanes Abdeel
Published: March 2021

1.Masalah Penelitian Gereja dan kemiskinan, permasalahan kemiskinan bukan hanya menjadi masalah local namun sudah menjadi tantangan secara Global. Gereja sebagai mandataris Tuhan dituntut untuk dapat berperan membantu masalah kemiskinana serta untuk menyuarakan ketidak adilan dan penindasan hak-hak orang miskin. Gereja sebagai mandataris Tuhan di tengah dunia, dituntut untuk dapat berperan dalam membantu masalah kemiskinan.
Analisis Jurnal "Ritual Mistis di Dunia Politik: Studi pada Ritual Ngalap Berkah di Gunung Kemukus"
Authors: P Epafroditus Surindra
Published: March 2021

Menganalisa isi jurnal "Ritual Mistis di Dunia Politik: Studi pada Ritual Ngalap Berkah di Gunung Kemukus: yang dibuat oleh Fibry Jati Nugroho.
SAMD3 is differentially expressed in lymph node metastasis in human breast cancer.
Authors: Mamoor Shahan
Published: March 2021

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). Between the breast and the brain reside the secondary lymphoid organ, the lymph nodes. We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with metastasis to the lymph nodes in humans with metastatic breast cancer. We found that sterile alpha motif domain containing 3, SAMD3, was among the genes whose expression was most different in the lymph node metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. Analysis of a separate microarray dataset revealed that SAMD3 was also differentially expressed in brain metastatic tissues. SAMD3 mRNA was present at increased quantities in lymph node metastases as compared to primary tumors of the breast. Importantly, expression of SAMD3 in primary tumors of the breast was correlated with patient overall survival, in lymph node positive patients but not in lymph node negative patients. Modulation of SAMD3 expression may be relevant to the biology by which tumor cells metastasize from the breast to the lymph nodes and the brain in humans with metastatic breast cancer.
Gendered cities: Studying urban gender bias through street names
Authors: Oto-Peralías Daniel , Gutiérrez Mora Dolores
Published: March 2021

This paper uses text analysis to measure gender bias in cities through the use of street names. Focusing on the case of Spain, we collect data on 15 million street names to analyze gender inequality in urban toponyms. We calculate for each Spanish municipality and each year from 2001 to 2020 a variable measuring the percentage of streets with female names over the total number of streets with male and female names. Our results reveal a strong gender imbalance in Spanish cities: the percentage of streets named after women is only 12% in 2020. We also observe substantial intra-urban differences, with female named streets being relatively scarcer in town centers. Concerning new streets, gender bias is lower but still far from parity. The second part of the paper analyzes the correlation of our indicator of gender bias in street names with variables related to gender attitudes and values, with the results suggesting that it constitutes a useful cultural measure of gender equality at the city level. This study thus helps to measure a relevant phenomenon, given the strong symbolic power attributed to street names, which has been elusive to quantify so far.
The impact of COVID-19 on air passenger demand and CO2 emissions in Brazil
Authors: Bazzo Vieira João Pedro , Braga Carlos Kauê Vieira , Pereira Rafael H. M.
Published: March 2021

The drastic reduction in economic activities caused by the COVID-19 pandemic creates a unique and timely opportunity to examine the environmental impacts of human activity. In several countries, the aviation sector was dramatically affected by the travel restrictions, resulting in a change of trip demand and in a drop of fuel consumption. Nonetheless, little attention has been paid to the impact of the pandemic on air travel demand, one of the fastest-growing sources of emissions globally. This paper estimates the impact of the COVID-19 on air travel demand and emissions in Brazil, the largest aviation market in Latin America. Combining detailed flight data with daily number of passengers and fuel consumption and data on combustion emission factors, we estimate CO2 emissions of domestic flights in Brazil. A Bayesian structural time-series model was used to estimate the impact of COVID-19 on daily trends of air travel demand and emissions. We find that the COVID-19 pandemic caused a reduction of 68% on national passengers and 62% in total CO2 emissions compared to what would have occurred if the pandemic had not happened. It avoided a total of approximately 4.6 megatons of CO2 between March and December 2020 in Brazil, the equivalent of one year of domestic flight emissions in France. Despite such a sharp drop in commercial aviation, passenger demand recovered to 64.2% of pre-pandemic levels by the end of 2020. CO2 emissions had a 52.6% reduction in 2020 and the emissions per capita increased after the COVID-19 outbreak. Although the precise impact of the COVID-19 on this figure is not yet fully understood, the fast recovery in domestic flights by December 2020 indicates that the emissions could soon return to pre-pandemic levels, demonstrating the challenges of reducing emissions in the aviation sector in the short term.
Analalisis Jurnal : PENDAMPINGAN PASTORAL HOLISTIK: SEBUAH USULAN KONSEPTUAL PEMBINAAN WARGA GEREJA
Authors: Lumbantoruan Erwinson Michael Palti
Published: March 2021

Pendampingan Pastoral Holistik:Sebuah Usulan Konseptual Pembinaan Warga Gereja. Gereja yang kuat terbentuk dari jemaat yang kuat. Jemaat yang kuat didapat dari pendampingan pastoral yang secara aktif menyentuh keseluruhan kehidupan warga gerejanya. Gereja perlu berusaha mengembangkan pendampingan pastoral holistik kepada jemaatnya. Berbagai program yang dirancang digunakan untuk mencapai sebuah pendampingan pastoral holistik. Jemaat yang multikultur disertai dengan multiproblem, mengharuskan para pelaku pastoral mengatur strategi dan menyusun model untuk dapat memberikan pelayanan pendampingan pastoral holistik kepada warga gerejanya. Konsep pendampingan pastoral holistik dari Howard Clinebell dan Totok Wiryasaputra akan membantu menganalisis dalam kerangka membuat pembinaan warga gereja secara holistik. Kerangka teoretis tersebut akan dipadukan dengan model pastoral yang dikembangkan oleh David Yonggi Cho di Yoido Full Gospel Church. Konsep dan model pendampingan pastoral holistik saling menopang serta menjadi “pisau bedah” dari pendampingan pastoral yang bermuara kepada efektifitas pemberdayaan kaum awam dan metode kelompok kecil.
THE IMPORTANCE OF PLANTING CHARACTER EDUCATION
Authors: Felta Felta
Published: March 2021

Education is an important pillar in the development of children's cognition. Since the beginning of human civilization, it was there that education emerged. Education is a series in the way of acquiring knowledge and self-perfection which is carried out by humans continuously or continuously. Humans are not free from limitations and shortcomings so that to complement these limitations and shortcomings, humans must process, one of which is through the acquisition of knowledge through education. Education obtained by humans is not only through formal education but early education obtained by humans is through the family environment and the community environment.
Gereja Dan Kemiskinan: Diskurus Peran Gereja Di Tengah Kemiskinan
Authors: Yesach Rai
Published: March 2021

Fibry Jati Nugroho, Gereja dan Kemiskinan: Diskursus Peran Gereja di Tengah Kemiskinan.Permasalahan kemiskinan bukan hanya menjadi masalah lokal, namun menjadi masalah yang digumulkanoleh dunia. Gereja sebagai mandataris Tuhan di tengah dunia, dituntut untuk dapat berperan dalammembantu masalah kemiskinan. Bagaimanakah sewajarnya gereja berperan di tengah kemiskinanmasyarakat? Dengan menggunakan metode deskriptif analisis, serta meminjam pemikiran Karl Marx,untuk menelisik peran gereja dalam membantu mengatasi permasalahan kemiskinan. Panggilan gerejayang seharusnya adalah untuk menyuarakan ketidakadilan dan penindasan hak-hak orang miskin. Gerejahadir untuk berpihak kepada yang lemah, tidak berdaya, miskin, dan yang terpinggirkan. Jika gereja tidakmemiliki keperpihakan kepada yang lemah, maka kehadiran gereja tidak memiliki makna. Gereja perluterus menerus menyuarakan kritik profetisnya tanpa pandang bulu terhadap berbagai penyalahgunaankekuasaan, terjadinya ketidakadilan, terampasnya hak-hak masyarakat, dan terhadap sistim yangmenindas serta memiskinkan manusia. Spiritualitas dan religiusitas jemaat juga harus sampai kepadasebuah kesalehan sosial, di mana energi spiritual yang dimiliki jemaat mampu untuk mendorongkepeduliannya akan berbagai persoalan kehidupan masyarakat. Spiritualitas seperti inilah yang harusmenjadi perhatian gereja dalam membangun kehidupan jemaat. Salib harus dipahami sebagai refleksi ataspenderitaan dan kematian Kristus, namun di saat yang sama pula harus mampu membuka mata dantelinga akan penderitaan, kesengsaraan, dan pengharapan manusia akan harkat dan martabatnya sebagaimanusia. Disitulah gereja berperan.
Cẩn trọng với sự quay trở lại của lạm phát
Authors: Si H.L. Cu
Published: March 2021

Hiệu ứng kép của thiếu thanh khoản, thường trực với phá sản kỹ thuật và lạm phát vẫn lởn vởn.
The Roman mosaics of triclinia in Antioch
Authors: Alshaieb Mohamad Moutaz
Published: March 2021

Presentation Title: The Roman mosaics of triclinia in AntiochResearch focus: The four designs of triclinia mosaics in AntiochSchool: Pázmány Péter Catholic University – Budapest, Hungary.Student Level: PhDPresentation Type: Poster Presentation AbstractThe Roman triclinia mosaics of Antioch are among the most interesting discoveries due to their premium Roman designs. These mosaics show significant Hellenistic artistic heritage in the representation of the classical and mythological topics (e.g. Iphigenia, Narcissus etc.) The main aim in this study was to classify the triclinia mosaics in Antioch according to their designs and to record them in a complex database including their topics, date, dimensions, exposures in order to determine possible connections between design elements and building types.Doro Levi in his book of 1947 “Antioch mosaic pavements” established the classical typology of Antiochian mosaics (T, U and Horseshoe shapes). However, I managed to identify a new design unnoticed by Levi, which I named H-shape design. This is composed of two large separated panels along the room, one with geometric motifs close to the rear wall and the second with figural representation close to the entrance and facing the rear wall.