bluuebunny/crossref_metadata_2025 huggingface dataset:
First- or Second-Mover Advantage? The Case of IT-Enabled Platform Markets
Authors: Feng Haiyang , Jiang Zhengrui , Li Minqiang , Feng Nan
Published: October 2024

Information technology-enabled platforms are playing an increasingly important role in the global economy. While some successful platforms entered their respective markets as pioneers, others were able to achieve market dominance despite starting as followers. This study investigates the conditions under which first-mover advantage (FMA) or second-mover advantage (SMA) occurs in a platform market, and derives their equilibrium order of market entries and optimal market entry timing. The first three determinants of FMA and SMA we identify are (1) quality improvement rate of the second mover, (2) length of demand window, and (3) length of market growth phase of demand window. When the two companies’ order of market entries is predetermined, the second mover having a higher initial platform quality than the first mover guarantees SMA, whereas the first mover having a higher initial platform quality than the second mover does not ensure FMA. In the latter case, the three determinants are needed to determine FMA and SMA. When the two companies’ order of market entries is endogenous, if any of the three determinants is sufficiently small, preemptive entry, in which both companies prefer to move early, is the equilibrium; otherwise, sequential entry, in which one company prefers to move early and the other prefers to move late, becomes the equilibrium in most cases. We also find that strong (same-side) network effects can weaken SMA and increase the possibility that both companies prefer early market entry, whereas strong cross-side network effects may strengthen SMA and increase the possibility that both companies prefer late market entry.
Seasonal Solar Thermal Absorption Energy Storage Development
Authors: Daguenet-Frick Xavier , Gantenbein Paul , Rommel Mathias , Fumey Benjamin , Weber Robert , Goonesekera Kanishka , Williamson Tommy
Published: October 2024

This article describes a thermochemical seasonal storage with emphasis on the development of a reaction zone for an absorption/desorption unit. The heat and mass exchanges are modelled and the design of a suitable reaction zone is explained. A tube bundle concept is retained for the
heat and mass exchangers and the units are manufactured and commissioned. Furthermore, experimental results of both absorption and desorption processes are presented and the exchanged power is compared to the results of the simulations.
Using an Expert’s Opinion to Establish Circumstances when Checking a Crime Report
Authors: Овсянников И.В.
Published: October 2024

В статье обращается внимание на повышенную сложность оценки заключения эксперта, на необходимость его оценки с точки зрения относимости, допустимости, достоверности, а также с точки зрения научной и логической обоснованности, внутренней непротиворечивости, подтвержденности выводов результатами исследования. Обосновывается, что ограниченные возможности (при проверке сообщения о преступлении) собирания других доказательств, необходимых для проверки и оценки заключения эксперта, и невозможность допроса эксперта препятствуют обоснованию постановления об отказе в возбуждении уголовного дела его заключением.

The article draws attention to the increased complexity of assessing an expert’s opinion, to the need to evaluate it from the point of view of relevance, admissibility, reliability, as well as from the point of view of scientific and logical validity, internal consistency, and confirmation of conclusions by research results. It is substantiated that the limited possibilities (when checking a report of a crime) of collecting other evidence necessary to verify and evaluate the expert’s conclusion, and the impossibility of interrogating the expert, prevent the decision to refuse to initiate a criminal case from being justified by his conclusion.
Legal Regulation of the Protection of Sika Deer. Inclusion of the Territory of their Reproduction in the Category of Specially Protected Natural Areas
Authors: Латипова Р.А.
Published: October 2024

Пятнистые олени являются ценным элементом биосферы, что обусловлено их устойчивым положением как в пищевой цепи, так и в экономике государства. Развитие туризма, получение коммерческой выгоды от продажи рогов животных и иные антропогенные факторы могут негативно повлиять на популяцию пятнистых оленей. По этой причине мы предлагаем оптимальное решение данной экологической проблемы — включение территории их воспроизводства в категорию особо охраняемых природных территорий.

Sika deer are a valuable element of the biosphere, which is due to their stable position both in the food chain and in the state economy. Tourism development, commercial profit from the sale of animal antlers and other anthropogenic factors can negatively affect the population of sika deer. For this reason, we propose an optimal solution to this environmental problem - inclusion of the territory of their reproduction in the category of specially protected natural areas.
Legal Basis for Employment and Organizational Basis for Combating Illegal Employment
Authors: Колобова С.В.
Published: October 2024

В статье анализируются нормы Федерального закона от 12 декабря 2023 г. № 565 «О занятости населения в Российской Федерации». Краткий сравнительный анализ Закона РФ от 19 апреля 1991 г. «О занятости населения в Российской Федерации» (утратит силу с 1 января 2025 г.) и нового Закона о занятости населения позволил выделить наиболее существенные изменения в данной сфере. Автором рассматриваются правовые последствия неформальной занятости, которой охватываются такие нарушения трудовых прав, как неоформление трудовых отношений в соответствии с ТК РФ, подмена трудовых договоров гражданско-правовыми. В статье обращено внимание на то, что новые формы занятости, в частности платформенная занятость, не регулируются трудовым законодательством, и обосновывается необходимость правовой регламентации возникающих отношений. Автор отмечает, что легализация трудовых отношений выступает решительной мерой борьбы с теневой занятостью; в этой связи приводятся аргументы в поддержку предложений по совершенствованию правовых механизмов в борьбе с неформальной занятостью.

The article analyzes the norms of the new Federal Law of December 12, 2023 No. 565 “On employment in the Russian Federation”. A brief comparative analysis of the Law of the Russian Federation of April 19, 1991 “On Employment of the Population in the Russian Federation” (will expire from January 1, 2025) and the new Law made it possible to highlight the most significant changes in this area. The author examines the legal consequences of informal employment, which covers such violations of labor rights as failure to formalize labor relations in accordance with the Labor Code of the Russian Federation, substitution of employment contracts with civil law ones. The article draws attention to the fact that the new form of employment, in particular platform employment, is not regulated by labor legislation, and substantiates the need for legal regulation of emerging relations. The author notes that the legalization of labor relations is a decisive measure to combat shadow employment; in this regard, arguments are given in support of proposals to improve legal mechanisms in the fight against informal employment.
التحول الرقمي ودوره في جودة العملية التعليمية لمعلمات المرحلة الابتدائية في مدينة الرياض
Authors: حمدي رهف علي , البشر سعود غسان
Published: October 2024

هدفت الدراسة إلى التعرف على واقع التحول الرقمي ودوره في تحسين جودة العملية التعليمية للمعلمات في المرحلة الابتدائية في مدينة الرياض، ومعرفة واقع البنية التحتية والموارد الرقمية والتحديات التي تحد من عملية التحول الرقمي. استخدم البحث المنهج الوصفي التحليلي. واعتمد الاستبانة كأداة لجمع البيانات اللازمة للدراسة، وقد تكونت عينة الدراسة من 180 معلمة بالمرحلة الابتدائية في مدينة الرياض. وبعد إجراء التحليل الإحصائي اللازم توصلت الدراسة إلى عدد من النتائج أهمها: أن هناك نظام فعّال لحماية البيانات الرقمية المستخدمة في العملية التعليمية. كما أنه يتم تدريب المعلمات على استخدام التكنولوجيا بصورة دورية. وأن ضعف شبكات الانترنت يؤثر على جودة التعليم الرقمي. وفي ضوء هذه النتائج قدمت الباحثة مجموعة من التوصيات تمثلت في: تطوير برامج تدريبية مستمرة للمعلمات وتحسين البنية التحتية التكنولوجية. بجانب تعزيز التعاون مع الخبراء في مجال التكنولوجيا التعليمية.
وسائل دعوة الرسل: دراسة تحليلية في دعوة نبي الله إبراهيم عليه السلام
Authors: الأحمري هيله علي محمد , الزاملي أحمد علي
Published: October 2024

تهدف هذه الدراسة الأكاديمية لموضوع "وسائل دعوة الرسل: دراسة تحليلية في دعوة نبي الله إبراهيم عليه السلام" إلى تحليل الوسائل الدعوية التي استخدمها نبي الله إبراهيم عليه السلام في دعوته إلى توحيد الله عز وجل والإخلاص في العبادة، وتسعى الدراسة إلى توضيح وتفصيل هذه الوسائل، مثل الحكمة والموعظة الحسنة وإقامة الحجة والصبر على الأذى، من خلال استكشاف دورها الفاعل في تحقيق أهداف الدعوة، بالإضافة إلى ذلك، تهدف الدراسة إلى تقديم توصيات لتطبيق هذه الوسائل في السياق الدعوي المعاصر، بما يعزز من الفهم والدعوة الإسلامية ويتيح تطبيقاتها بشكل فعال في المجتمع الحديث. وتتضمن الدراسة تحليلًا معمقًا للوسائل الدعوية لنبي الله إبراهيم عليه السلام، بما في ذلك الحكمة والموعظة الحسنة وإقامة الحجة والصبر على الأذى، كما تستعرض التطبيقات المعاصرة لهذه الوسائل وكيفية الاستفادة منها في الدعوة الحديثة، والنتائج أظهرت أن نبي الله إبراهيم عليه السلام استخدم وسائل متعددة في دعوته، مثل الحوار العقلي، وإقامة الحجة، والصبر على الأذى، مما كان له تأثير كبير في نشر دعوته وتوحيد الله، وأكدت الدراسة أن تطبيق هذه الوسائل في الدعوة المعاصرة يمكن أن يزيد من فاعلية الدعوة ونجاحها في المجتمع الحديث، تُبرز الدروس المستخلصة أهمية الأخلاق في الدعوة وأهمية دراسة حياة الأنبياء كمصدر للإلهام والتعليم، وقد اعتمدت الدراسة المنهج التحليلي الاستقرائي لتحليل وتأصيل المسائل الشرعية، مستندة إلى النصوص الدينية والأدلة العقلية.
Self-Assembly of Amorphous, pH-Degradable Polymer Nanodiscs of Controllable Size and Functionality
Authors: Zeng Haoxiang , Baek Jinsu , Kim Byeong-Su , Muellner Markus
Published: October 2024

Amphiphilic bottlebrush block copolymers (BBC) with tadpole-like, coil-rod architecture can be used to self-assemble into functional polymer nanodiscs directly in water. The hydrophobic segments of the BBC were tuned via the ratio of ethoxy-ethyl glycidyl ether (EE) to tetrahydropyranyl glycidyl ether (TP) within the grafted polymer sidechains. In turn, this variation controlled the sizes, pH-responsiveness, and drug loading capacity of the self-assembled nanodiscs. Notably, as EE exhibited faster hydrolysis than TP, the nanodiscs featured variable degradation rates under mild acidic conditions, aiding small molecule release and time-dependent and complete degradation of discs into fully water-soluble copolymers.
Electrostatic Embedding Machine Learning for Ground and Excited State Molecular Dynamics of Solvated Molecules
Authors: Mazzeo Patrizia , Cignoni Edoardo , Arcidiacono Amanda , Cupellini Lorenzo , Mennucci Benedetta
Published: October 2024

The application of quantum mechanics (QM) / molecular mechanics (MM) models for studying dynamics in complex systems is nowadays well established. However, their significant limitation is the high computational cost, which restricts their use for larger systems and long-timescale processes. We propose a machine-learning (ML) based approach to study the dynamics of solvated molecules on the ground- and excited-state potential energy surfaces. Our ML model is trained on QM/MM calculations and is designed to predict energies and forces within an electrostatic embedding framework. We built a socket-based interface of our machinery with AMBER to run ML/MM molecular dynamics simulations. As an application, we investigated the excited state intramolecular proton transfer of 3-hydroxyflavone in two different solvents: methanol and methylcyclohexane. Our ML/MM simulations accurately distinguished between the two solvents, effectively reproducing the solvent effects on proton transfer dynamics.
Discrete and mixed-variable experimental design with surrogate-based approach
Authors: Zhu Mengjia , Mroz Austin , Gui Lingfeng , Jelfs Kim , Bemporad Alberto , del Río Chanona Ehecatl Antonio , Lee Ye Seol
Published: October 2024

Experimental design plays an important role in efficiently acquiring informative data for system characterization and deriving robust conclusions under resource limitations. Recent advancements in high-throughput experimentation coupled with machine learning have notably improved experimental procedures. While Bayesian optimization (BO) has undeniably revolutionized the landscape of optimization in experimental design, especially in the chemical domain, it is important to recognize the role of other surrogate-based approaches in conventional chemistry optimization problems. This is particularly relevant for chemical problems involving mixed-variable design space with mixed-variable physical constraints, where conventional BO approaches struggle to obtain feasible samples during the acquisition step while maintaining exploration capability. In this paper, we demonstrate that integrating mixed-integer optimization strategies is one way to address these challenges effectively. Specifically, we propose the utilization of mixed-integer surrogates and acquisition functions—methods that offer inherent compatibility with problems with discrete and mixed-variable design space. This work focuses on Piecewise Affine Surrogate-based optimization (PWAS), a surrogate model capable of handling medium-sized mixed-variable problems (up to around 100 variables after encoding) subject to known linear constraints. We demonstrate the effectiveness of this approach in optimizing experimental planning through three case studies. By benchmarking PWAS against state-of-the-art optimization algorithms, including genetic algorithms and BO variants, we offer insights into the practical applicability of mixed-integer surrogates, with emphasis on problems subject to known discrete/mixed-variable linear constraints.
NETWORK ANALYSIS OF THE ORGANIC CHEMISTRY IN PATENTS, LITERATURE, AND PHARMACEUTICAL INDUSTRY
Authors: Kogej Thierry , Svensson Emma , Rydholm Emma , Bastys Tomas , Kannas Christos , Kabeshov Mikhail , Genheden Samuel , Engkvist Ola
Published: October 2024

Chemical reactions can be connected in large networks such as knowledge graphs. In this way, prior work has been able to draw meaningful conclusions about the structures and properties of the included organic chemistry. However, the research has focused on public sources of organic chemistry that might lack the intricate details of the synthesis routes used in in-house drug discovery. In this work, we expand on previous analyses to also include an in-house electronic lab notebook (ELN), such that important differences between the network architectures can be investigated. Three chemical reaction knowledge graphs were constructed from US Patent and Trademark Office (USPTO), Reaxys, and an in-house ELN, respectively. The three knowledge graphs were compared. We found that the Reaxys knowledge graph is the most interconnected, whereas the USPTO and ELN knowledge graphs appear more arranged around a few central nodes. These differences might be attributed to the different origins of the data in the three sources.
"Double-Use" Strategy for Improving the Photoelectrochemi-cal Performance of BiVO4 Photoanodes using a Cobalt-Functionalized Polyoxotungstate
Authors: Feng Fan , Mitoraj Dariusz , Oseghe Ekemena , Streb Carsten , Beranek Radim
Published: October 2024

ABSTRACT: A ‘Double-Use’ strategy for the development of high-performance bismuth vanadate (BiVO4) photoanodes for solar water splitting is reported, where a molecular cobalt-phosphotungstate (CoPOM = Na10[Co4(H2O)2(PW9O34)2]) is used both as a bulk doping agent as well as a surface-deposited water oxidation co-catalyst. The use of CoPOM for bulk doping of BiVO4 is shown to enhance the electrical conductivity and improve the charge separation efficiency, resulting in the enhancement of the maximum applied-bias photoconversion efficiency (ABPE) by a factor of ~18 to 0.54% at 0.87 V vs. RHE, as compared to pris-tine BiVO4 (0.03% at 1.04 V vs. RHE). In addition, modification of CoPOM-doped BiVO4 with CoPOM as a surface co-catalyst enhances the hole extraction and improves the water oxidation kinetics, resulting in the overall enhancement of the ABPE to 0.79% (at 0.82 V vs. RHE), i.e. by a factor of ~26 with respect to pristine BiVO4. This study establishes the ‘double-use’ strategy involving CoPOMs as an effective, straightforward and easily scalable approach for the development of high-quality photoanodes for solar water splitting, and highlights the future potential of utilizing well-designed polyoxometalates as precursors for the syn-thesis of energy materials.
Ligand-Solvent Library Design for Tailoring Interparticle Interactions in Colloidal Nanocrystals
Authors: Deng Meng , Li Chuncheng , Liu Lei , Fan Zhaochuan
Published: October 2024

This study explores the critical role of nonpolar ligand-solvent in modulating interparticle interactions in colloidal nanocrystals, which profoundly affects colloidal stability and enables bottom-up precision self-assembly. We created a library comprising 28 distinct ligands and three different solvents to investigate how the position of various modifications—specifically double bond, branched chain, benzene ring, and naphthalene ring—influence ligand crystallinity and interparticle attraction in nonpolar solvents. Through explicit solvent simulations, we demonstrated that placing molecular fragments near the head group or in the midsection of the ligand chain leads to disordered ligand structure, diminishing interparticle attraction, while terminal positioning fosters ordered ligand packing and attractive interactions. By fine-tuning fragment positions or combining two fragments, we achieved control over the crystallinity of ligand bundles, thereby influencing the attraction in the "touch" mode. Additionally, we examine the effects of solvent size on solvation, revealing its potential to independently control attraction in the "lock" mode. These findings enhance our understanding of ligand-solvent dynamics and lay the groundwork for the precise manipulation of nanocrystal self-assembly.
Visualization of photocuring and 4D printing with real-time phosphorescence
Authors: Gu Fan , Ji Mengxing , Zhang Lisha , Zhao Tengjiao , Zhang Ruiqing , Lv Xia , Tian He , Ma Xiang
Published: October 2024

Competitive candidates with advantageous pure organic room-temperature phosphorescence (RTP) are brought into the fields of photocuring and 4D printing materials. Based on the phosphorescent regulations with internal changes of surrounding environments, we innovatively put forward a strategy to introduce phosphors into photocuring materials because of the liquid-to-solid transformation. Based on this, the obtained luminescent curing films achieve remarkable RTP emission with full-color display of blue, green, and orange. Visible real-time monitoring can be realized by observations of phosphorescent changes, thus allowing the recording of curing speed, internal environment, and conversion during the curing process. Moreover, these new curing materials successfully complete 4D printing and shape-memory process, demonstrating continuous dynamic deformation in fabricated 2D materials (the fabricated flower-pattern film) and 3D materials (the spaceman and pandas) with vivid RTP emission. Especially, the further regulations of the real-time phosphorescence can realize significant visualization in these 4D printing materials. We believe this discovery with the replacement of phosphors opens a door to further extension in the field of curing materials and more sophisticated morphing in 4D printing.
Extending Density-Corrected Density Functional Theory to Large Molecular Systems
Authors: Kim Youngsam , Sim Mingyu , Lee Minhyeok , Kim Sehun , Song Suhwan , Burke Kieron , Sim Eunji
Published: October 2024

Practical density-corrected density functional theory (DC-DFT) calculations rely on Hartree-Fock (HF) densities, which can be computationally expensive for systems with over a hundred atoms. We extend the applicability of HF-DFT using the dual-basis method, where the density matrix from a smaller basis set is used to estimate the HF solution on a larger basis set. Benchmarks on many systems, including the GMTKN55 database for main-group chemistry, and the L7 and S6L datasets for large molecular systems demonstrate the efficacy of our approach. We apply the dual-basis method to both DNA and HIV systems, and compare with the literature. A careful reparameterisation of HF-r2SCAN-DC4 eliminates the negative s8 coefficient, with no loss of performance.
Approach to: Ptosis
Authors: Patil Nikhil , Adnan Pirbhai
Published: October 2024

Question 
A 75-year-old male presents to the ophthalmology service with a drooping left upper eyelid. Upon further questioning, he states that he feels his visual acuity has deteriorated in the left eye, but only in the dark. On testing his best corrected visual acuity is 20/25 in the right eye and 20/30 in the left eye. His pupils are equal, round, and reactive to light and accommodation. His intraocular pressures are 14mmHg bilaterally. His past medical history is significant for type 2 diabetes mellitus, hypertension, hypercholesterolemia, and obesity. He states that his dropping eyelid does not get better or worse during the day and he first noticed his drooping eyelid this morning. He also states that he has been experiencing some horizontal diplopia since this morning. Your clinical examination reveals no significant ocular misalignment, but the patient is unable to fully adduct, infraduct, or supraduct his left eye. His margin to reflex distance 1 is 2mm and his levator function is markedly decreased. His ESR and CRP are within normal limits. He is scheduled for a follow-up visit in 6 weeks at which point his symptoms have almost completely resolved.

Third Nerve palsy
Myasthenia gravis
Congenital ptosis
Horner syndrome
Aponeurotic ptosis

Answer

A) Given his history and clinical examination, this patient likely has a third cranial nerve palsy. Furthermore, given no pupillary involvement and systemic risk factors (obesity, diabetes mellitus, hypertension, hypercholesterolemia), an ischemic third nerve palsy is favoured. Typically, ischemic third nerve palsies are self-resolving and the patient can be scheduled for follow-up in 4-6 weeks. Pupil involvement or a lack of improvement at follow-up are indications for head imaging (CT angiography) to rule out an aneurysm or other compressive causes. In this case, since the ptosis does not worsen as the day goes on and improve after rest, myasthenia gravis is unlikely. Additionally, this autoimmune condition would present at an earlier age than 75. Similarly, congenital ptosis would present in the first years of life. Horner syndrome would include miosis and facial anhidrosis alongside the ptosis. Aponeurotic ptosis is a possible diagnosis, however, is less likely given this presentation with an inability to fully adduct, infraduct, or supraduct his left eye.
CONTEMPORARY ASPECTS OF CYBERTERRORISM MOTIVATED BY RELIGION
Authors:   AL-FARABI KAZAKH NATIONAL UNIVERSITY, Kurmanaliyev Maksat , Amankul Temur , Sarsembayev Ruslan , Tungatova Ulzhan
Published: October 2024

The article examines the subject of religious cyberterrorism, which is remains relevant in the contemporary discourse. The author underlines the possibility for terrorist organizations to form "sleeper cells" and "lone wolves" who can be deployed at any time to complete their missions. The article outlines religious terrorist organizations' goals and propaganda methods, as well as countermeasures and counter-propaganda strategies. The relationship between their goals and propaganda tactics, information, and psychological methods of persuasion employed by propagandists is examined. The purpose of this article is to examine the information strategy of terrorist group propagandists aimed at recruiting new combatants, as well as a qualitative examination of legal, technical, and counter-propaganda methods adopted by various governments throughout the world to counteract terrorist propaganda. The author lists countermeasures and evaluates each one's effectiveness. China is used as an example, as it is now the most effective in technological terms, despite criticism from human rights groups. As part of a counter-agitation approach, the experience of getting clergy to dispute terrorist organizations' religious doctrine is explored. It is concluded that, notwithstanding the defeat of ISIS, the problem of opposing religious terrorist propaganda operations remains relevant today. The most essential feature of the article is the investigation of this subject within the context of Kazakhstan.
EXPECTATIONS OF KAZAKHSTAN PR AGENCIES FOR PR GRADUATES’ SKILLS
Authors:   AL-FARABI KAZAKH NATIONAL UNIVERSITY, Filipov Milen
Published: October 2024

The study addresses the lack of comprehensive research on whether recent PR graduates in Kazakh- stan meet industry requirements. The research aimed to explore PR professionals’ satisfaction levels and opinions on the competency of PR graduates, highlighting key issues in PR education in Kazakh- stan. Adopting a pragmatic worldview, the study used qualitative methodologies, including document analysis and structured interviews with chief executive officers of PR agencies experienced in hiring entry-level graduates. Findings provide insights into PR agencies’ expectations of Kazakhstani universi- ties, specifically addressing the skills needed in the market. Soft skills: PR representatives emphasized responsibility, collaboration, initiative, stress management and time management. Effective communica- tion and collaboration were particularly noted for their impact on customer service outcomes. Technical skills: Essential competencies include data analysis, photo and video production/editing, data manage- ment, and search engine optimization (SEO). Professional skills: Key skills identified were copywriting, creating social media content, developing media relations materials, and making informed decisions based on quantitative and qualitative data. However, the study revealed a gap between PR agencies’ expectations and the actual skills of entry-level PR graduates. Noted deficiencies included a lack of practical experience and internship opportunities, as well as a shortage of qualified educators with rel- evant industry experience, contributing to graduates’ perceived inadequacies in practical PR skills. The study also explored PR agencies’ attitudes toward the ability of Kazakhstani universities to prepare PR graduates. Interview results indicated generally positive attitudes, with confidence in universities’ ability to develop technical skills. Collaboration between universities and PR agencies was seen as crucial for producing well-trained PR professionals.
DEEP FAKES IN THE DIGITAL MEDIA AGE: OPPORTUNITIES AND THREATS
Authors:   AL-FARABI KAZAKH NATIONAL UNIVERSITY, Yessimova Manshuk , Shevyakova Tatyana
Published: October 2024

The article is devoted to an urgent problem today – the technology of deepfakes in the context of the information society. Thanks to modern technologies and digital tools, the rapid development of artificial intelligence (hereinafter – AI), the problem of deepfakes is becoming more widespread, as their influence on public opinion, political decisions and knowledge is only increasing. Deepfakes provide opportuni- ties for spreading false information, exerting political influence, and even manipulating the image (using photos, videos and audio) of celebrities. The aim of the article is to understand these technologies, identify the challenges and threats associ- ated with them, and develop countermeasures. The hypothesis of the study. In the era of digital media, deepfakes are powerful tool that can be used both to create positive innovations in various fields (for example, entertainment, education, marketing, etc.) and to spread disinformation and manipulation in the media space, which poses significant threats to public and information security. The practical significance of the work lies in the fact, that research in the field of deepfakes can contribute to the development of tools and methods for detecting and analyzing this kind of content. Research methods include general scientific, special scientific and specific scientific methods (con- tent analysis, generalization, comparison, etc.). The results of the study may be useful in further research of technologies deepfakes in the informa- tion space, as well as being useful in recognizing false AI-generated content.
Yüksek Öğretim Kurumlarında Sayıştay Denetimlerinin Etkinliğinin Ölçülmesi ve Değerlendirilmesi (Measurement And Evaluation of The Effectiveness of Court of Accounts Audits in Higher Education Institutions)
Authors: Kurt Ganite , Bozkurt Yazar Birgül
Published: October 2024

Bu çalışmada üniversitelere yönelik yapılan düzenlilik denetim raporlarından elde edilen bulgulardan yola çıkarak yüksek öğretim kurumlarında sayıştay denetimlerinin etkinliğinin ölçülmesi ve değerlendirilmesiamaçlanmaktadır.Ayrıca çalışma, yüksek öğretim kurumlarında yapılan Sayıştay düzenlilik denetimlerinde elde edilen bulguların dikkate alınıp alınmadığı, tespit edilen eksikliklerin sonraki dönemlerde giderilip giderilmediği ve bu surecin hizmet kullanıcıları açısından sonuçlarının tespit edilmesi ile ilgilidir.Bu bağlamda 2022-2019 yılları arasında her coğrafi bölgeden biri kuruluş tarihi itibarı ile eski ve nispeten daha yeni olmak üzere toplam 14 üniversitenin kamuoyu ile paylaştıkları toplam 49 düzenlilik denetim raporu içerik analiz yöntemine göre değerlendirilmiştir. Gerçekleştirilen analizin bulgularıngenelolarak muhasebe kalemlerininyanlış kullanımı ile ilgili olaraküniversitelerde görevli personellerin gerekli eğitim ve yeterliliğe sahip olmaları gerektiğini göstermiştir. Yapılan denetim çalışmalarında genel olarak olumlu görüş bildirilmiştir. Bu uygulama yerine, denetim görüşünün dayandığı bulgular çerçevesinde şartlı görüş bildirilmesinin denetimin etkinliğini artıracağı düşünülmektedir.Çünkü incelenen denetim raporlarındaki bu bulguların nicel olarak fazla olmasıdurumundaşartlı görüş bildirilmesinin kurum çalışanlarının hatalarını düzeltmesi veya kurum içinde yeni hataların oluşmasını önleyeceği düşünülmektedir. Ayrıca kamu zararı ile ilgili işlemlerin izlenmesine ilişkin bir sonraki yılda açıklama yapılmasının kamuoyunun güveninin kazanılması açısından önemli olduğu düşünülmektedir.
MULHERES REGENTES EM BANDAS DE MÚSICA: DESAFIOS E POSSIBILIDADES NO CONTEXTO DE SANTA CATARINA
Authors: Guerra Bioni Bianca , Schambeck Regina Finck
Published: October 2024

O texto se propõe a discutir os desafios e possibilidades de atuação de cinco mulheres regentes que atuam em bandas de música no contexto de Santa Catarina. A pesquisa seguiu os princípios da abordagem qualitativa, com recolha de dados mediante a utilização de questionário de sondagem inicial e entrevista semiestruturada. Foram selecionadas quatro regentes que atuam em bandas de música vinculadas ao Programa de Bandas e Fanfarras e uma regente de banda de música que atua em contexto não educacional. Foi possível observar que ainda existe no estado de Santa Catarina uma baixa representação de mulheres atuando como regentes em bandas de música. As participantes da pesquisa reconhecem que a presença de mulheres como instrumentistas nesses agrupamentos pode contribuir para ampliar o número de mulheres regendo nesse contexto. Para tanto, mencionam a importância da formação de uma rede de apoio entre mulheres, o apoio familiar, a necessidade de cursos de formação continuada e, principalmente, a necessidade de fóruns e debates sobre regência em bandas de música direcionados às mulheres, de modo a ajudar a construir estratégias de superação de dificuldades e do preconceito que ainda se apresenta quando é uma mulher que está à frente de uma banda de música.
Integrating Important Vaccination Issues into the Banjar Community Religious and Socio-Cultural Values
Authors: Husairi Ahmad , Husin Gt. Muhammad Irhamna , Rumboko Raihan Febri , Kurniawan Muhammad Immas
Published: October 2024

Background:  The important issues of vaccination need to be integrated between medical science, the Islamic religion and the religious-social-cultural values of the community. The integration is important to build public trust in the vaccination program.Objective: to integrate the important issues of vaccination into the religious and socio-cultural values of the Banjar community.Methods: The research was designed qualitatively based on a phenomenological paradigm through field observations and in-depth interviews with Banjar community participants who did not vaccinate and participants who were experts in medicine-immunology-Islamic law-social-cultural in the Banjar community. Results: The research showed that some Banjar people still did not understand the principles of vaccination, the concept of istihalah and herd immunity. The Banjar community was a religious society, that liked to work together and care about their fellow citizens.Conclusion: The principles of vaccination, istihalah, and herd immunity can be integrated with the Banjar community who are religious, like working together, and care about their fellow citizens to build public trust in the vaccination program.
The Cytoxic Effects Of Forest Honey (Apis dorsata) On T47D Breast Cancer Cells
Authors: Adnan Malik Hisyam , Rakhmawatie Maya Dian , Tursinawati Yanuarita
Published: October 2024

Background: In 2018, an estimated 2 million people had breast cancer. Forest honey (Apis dorsata) can have antioxidant activity due to the presence of flavonoid saponin, alkaloid, and tannin compound, therefore can be used as anticancer through the induction of apoptosis.Objective: To determine the IC50 of forest honey (Apis dorsata) on T47D breast cancer cells and see the morphology of T47D cells after administration of forest honey.Methods: This study is an in vitro test of the cytotoxic activity of forest honey against T47D breast cancer cells using the MTT assay method. The concentration of forest honey was prepared by the two-fold microdilution method in the range of 1000 - 31.25 µg/mL. Doxorubicin was used as a control drug with a concentration of 20 - 0.675 µg/mL. The morphology of T47D cells after treatment was observed with an inverted microscope with 400x magnification.Results: Forest honey (Apis dorsata) from any concentration did not show any inhibition of growth of T47D breast cancer cells. Meanwhile, doxorubicin had an IC50 of 3.746 µg/mL. The morphology of T47D cells with honey administration showed many live cells with formazan crystals.Conclusion: Forest honey has no cytotoxic activity against T47D breast cancer cells.
Hubungan antara Asesmen Kompetensi Minimum dan Kemampuan Berpikir Tingkat Tinggi pada Pembelajaran Matematika Siswa Kelas V SDN Jember Lor 03
Authors: Utama Refana Widya , Masyhud M. Sulthon , Alfarisi Ridho
Published: October 2024

This research is correlational research with product moment correlation analysis. This research uses quantitative methods using test instruments and documentation data from AKM simulation results. The aim of this research is to determine whether or not there is a relationship between the Minimum Competency Assessment and Higher Level Thinking Skills in Mathematics Learning for Class V Students at SDN Jember Lor 03. The research was carried out at SDN Jember Lor 03, Jember Regency. The subjects of this research were 82 class V students. The data analysis technique used was product moment correlation analysis. The correlation coefficient result is 0.478 which is greater than the r-table value of 0.213 so that the research results show that there is a positive and significant relationship between the minimum competency assessment and high-level thinking abilities in class V students and the results. The resulting determinant coefficient is 23%, meaning that the minimum competency assessment variable influences high-level thinking abilities by 23% and the remainder comes from other factors in the form of internal factors, namely the level of intelligence, intelligence, attention, interest, talent, motivation and readiness of students, external factors that influence including teaching methods, teacher and student relations, school programs and teaching facilities
THE UNIVERSITY PREPARATION OF STUDENTS – FUTURE TEACHERS IN THE FIELD OF DIGITAL TECHNOLOGIES
Authors:   University of National and World Economy, Sofia, Totseva Yanka , Valkova Rumina ,   University of National and World Economy, Sofia
Published: October 2024

In the current development, attention is directed to the curricula of the discipline ‘Information and communication technologies in education and work in a digital environment’, which is mandatory according to the Ordinance on the state requirements for acquiring the professional qualification teacher of Bulgarian universities preparing teachers in professional fields 1.2. pedagogy and 1.3. pedagogy of training in… in the educational-qualification degree bachelor. The relationship between the subjects offered in the curricula and the European framework for the digital competence of teachers (DigCompEdu) was sought, in order to determine whether the training in this discipline leads to the formation of competences in the six areas specified in it. Conclusions are drawn and recommendations are formulated for synchronizing the content with the digital competencies that, according to the framework, must be acquired.
Attribution of invasive group A streptococcal infections (iGAS) to predisposing viral infections, the Netherlands, 2010 to 2023
Authors: de Gier Brechje , van de Kassteele Jan , van Asten Liselotte , Schoffelen Annelot F ,   ISIS-AR study group, Hooiveld Mariette , te Wierik Margreet JM , van Sorge Nina M , de Melker Hester E
Published: October 2024

Background

After most COVID-19 pandemic control measures were lifted in 2022, many infectious diseases re-emerged. An increase in invasive group A streptococcal (iGAS) infections among adults and young children was reported by several countries. Viral infections including influenza and varicella, known risk factors for iGAS infection, also increased.

Aim

To estimate the proportion of GAS skin and soft tissue infections (SSTI) and pneumonia/sepsis in children (≤ 5 years) attributable to varicella, and the proportion of GAS pneumonia/sepsis in children and adults attributable to potentially predisposing respiratory viruses influenza A and B, RSV, hMPV and SARS-CoV-2 in the Netherlands.

Methods

We performed time series regression using weekly data on respiratory viruses, varicella and non-invasive GAS infections and GAS isolates cultured from blood, lower airways, skin, pus and wounds, from January 2010 to March 2023.

Results

In 2010–19, 50% (95% CI: 36–64) of GAS SSTI in children were attributable to varicella. Between January 2022 and March 2023, 34% (95% CI: 24–43) of GAS SSTI cases were attributable to varicella. Of iGAS pneumonia/sepsis between January 2022 and March 2023, 34% (95% CI: 20–49) and 25% (95% CI: 18–32) was attributable to respiratory virus infections in children and adults, respectively, with the largest contributor (17%) being influenza A.

Conclusions

Predisposing viral infections likely contributed to, but cannot fully explain, the observed iGAS increase among children and adults in 2022–23 in the Netherlands. Public health measures to control viral infections, such as vaccination against varicella or influenza, might reduce the iGAS disease burden.
Exploring Arabic Diglossia in Learning Kalām: Bridging the Gap in Daily Communication
Authors: Putri Annindita Hartono , Thoyyibah Anisatu
Published: October 2024

This study analyzes Arabic diglossia in terms of variety, context, and underlying factors in the teaching of speaking skills at the Markaz Arabiyah Pare institution in Kediri, focusing on the Akbarnas class program. The subjects of this research include students, speaking skills teachers, homeroom teachers, and the head of the curriculum. Using a qualitative descriptive method, data were collected through observation, interviews, and ethnographic documentation. Data analysis was conducted through data reduction, data presentation, and conclusion. The results indicate that formal language varieties dominate in the Akbarnas class program, complemented by non-formal language varieties to enhance students' linguistic skills. This diglossia is influenced by the language use system established at the institution and the experiences of Middle Eastern graduate teachers who are familiar with various forms of the Arabic language.
Experience of the implementation of non-formal adult education in the United Kingdom of Great Britain and Northern Ireland
Authors: Fedchyshyna Anastasiia
Published: October 2024

The article considers the experience of non-formal adult education in the United Kingdom of Great Britain and Northern Ireland. The author analyzes the main legal documents of the legislative regulation of adult education in the United Kingdom of Great Britain and Northern Ireland. The content of «non-formal adult education» is highlighted, which is considered as a structural element of lifelong learning that supplements the existing formal education and is a powerful tool for the sustainable development of society and the potential of each adult, in particular, increasing their competitiveness in the labour market.

Statistical data on the participation of the adult population of the United Kingdom of Great Britain and Northern Ireland in formal and non-formal learning have been analyzed, which allow us to assess comprehensively the state of development and functioning of the adult education system in this country. Modern forms of non-formal adult education in the United Kingdom of Great Britain and Northern Ireland are characterized, including professional courses and trainings, internships, massive open online courses, etc. Examples of educational programmes and training courses available at British universities, which are providers of educational services in the field of non-formal adult education, are given. Attention is focused on the features of validation of the results of non-formal adult education in the United Kingdom of Great Britain and Northern Ireland.

The author concludes that the experience of the implementation of non-formal adult education in the United Kingdom of Great Britain and Northern Ireland can serve as a certain reference point for the modernization of non-formal adult education in Ukraine, because the system of adult education in this country allows adults to adapt quickly to socio-economic challenges and realize themselves on employment and social security, economic growth and competitiveness.
Interactive Methods of Teaching Future Masters of Medicine in Marketing Communications
Authors: Marchuk Ivanna
Published: October 2024

The formation of future masters of medicine knowledge of marketing communication in order to develop personal professionalism and implement state policy in the field of health care is carried out through the establishment of balanced communication with consumers of medical services using the marketing environment of the healthcare market. Many market participants do not realize that effective communications directed at the consumer, provider, or health care provider are as much a business resource as finance or time. Interactive learning methods are designed to form future masters of medicine not only high-quality knowledge and practical skills in marketing communication, but also the ability to quickly respond to market needs, create an original product or perform non-standard tasks in non-standard conditions as well as to form the motivation of students of medical institutions of higher education of Ukraine to study. Creative tasks and exercises (in particular, creation of advertising for a product, brand of a trademark, programs of exhibitions or sales exhibitions, creation of corporate style of health care institutions) teach how to demonstrate a product or service; how to convince consumers to buy exactly such a product or exactly such a service; with the help of which levers healthcare institutions can create, use and promote the image of healthcare institutions, trademarks, brands, etc. It is necessary to learn how to rationally implement marketing communications in health care institutions, and interactive methods are focused specifically on the creation and promotion of one's own professional products, we consider them the most effective in the modern conditions of training future masters of medicine.
KONSEP KAFÄ€â€™AH DALAM Q.S AN-NUR AYAT 26 (PERSPEKTIF TAFSIR MAQASHIDI ABDUL MUSTAQIM)
Authors: Fauziah Fatimah Ummi , Hasan Moh. Abdul Kholiq
Published: October 2024

Penelitian ini mengkaji tentang konsep kafa'ah dalam Q.S An-Nur yang menjelaskan tentang kesetaraan jodoh, dengan menggunakan pendekatan metode tafsir maqashidi oleh Abdul Mustaqim. Jenis penelitian analisis deskriptif kualitatif, kemudian dianalisis dengan terlebih dahulu mengumpulkan ayat-ayat, data ilmiah, mendeskripsikan interpretasi mufassir, memaparkan ayat kafÄ'ah, dan melihat apakah hasilnya relevan dengan keadaan masyarakat saat ini. Yang mana akan menunjukkan maksud tentang pembelaan Allah terhadap Aisyah ra. akan tetapi dalam tafsir substansi maqashidi Q.S. an-NurÂ  menjelaskan tentang bagaimana persamaan pasangan akan memberikan peluang yang lebih besar untuk membentuk. Kemudian ditafsirkan dengan tafsir tekstual, kontekstual dan intertekstual. Hasil penelitian menunjukkan tentang pembelaan Allah terhadap Aisyah ra, Tafsir substansi maqashidi Q.S. an-Nur [24]: 26 adalah persamaan pasangan akan memberikan peluang yang lebih besar untuk membentuk keluarga yang sakinah, mawaddah warrahmah, dan setara yang dimaksud dalam ayat ini adalah sama dalam aturan, penzina, dan orang fasik. Kesetaraan dalam ayat ini bukanlah persamaan mutlak antara pasangan, tetapi hanya kecenderungan dan peluang untuk jodoh.
IJTIHAD IBNU HAJAR AL-ASQALANI DALAM MENGKONSTRUKSI ILMU HADIS
Authors: Saputra Muhamad Rama , Alif Muhammad
Published: October 2024

Ibnu Hajar al-Asqalani merupakan ulama hadis populer yang hidup pada abad ke 8 H. kepopulerannya itu kaya akan karya kitab-kitabnya, sehingga dengan karyanya itu Ibnu Hajar mendapatkan gelar Amirul Muâ€™minin fil hadis. Lantas dengan karya yang banyak itu, adakah pemikiran baru dan ijtihadnya yang sebelemunya tidak ada. Para ulama setelahnya banyak yang mengutip pada kajian hadis serta mengkodipikasikan dalam kitabnya, seperti al-Sakhawi, al-Suyuthi, al-Biqhaâ€™I, Zakaria al-Anshari dan lain-laoin. Pada peniltian ini diawali dengan historiografi, karya-karyanya, dan pemikirannya yang tertuang dalam kitabnya. Melalui penelitian bidang library research yang mengandalkan bahan penelitian dari perpustakaan, seperti buku, kitab, jurnal, ensiklopedia atau majalah sebagai sumber data untuk mencari dan melacak permasalahan tersebut. Adapun Hasil dan temuan penelitian ini, ijtihad Ibn Hajar al-â€˜Asqalani dalam bidang Ilmu hadis bahwa beliau layak disebut seorang mujtahid dalam bidang hadis atas dasar pemikirannya yang tertuang dalam karyanya yang mencapai 177 karya Ibnu Hajar dalam bidang hadis, serta dalam kitabnya banyak pemikiran baru yang ulama sebelumnya tidak ada.Â