bluuebunny/crossref_metadata_2025 huggingface dataset:
Simultaneous treatment of urolithiasis and cholelithiasis
Authors: Protoshchak Vladimir V. , Sivakov Alexey A. , Lychev Alexey B. , Gozalishvili Sergei M. , Kushnirenko Nikolay P. , Kharitonov Nikolay N. , Grafschina Elena N.
Published: October 2022

Urolithiasis and cholelithiasis are among the most common diseases among the adult population worldwide. The combination of these diseases requires the development of an individual approach in the treatment of each patient. This article presents a clinical case of a combination of urolithiasis complicated by terminal hydronephrosis with cholelithiasis. Successful simultaneous surgical treatment is described.
COVID-19 and tuberculosis reactivation: a systematic review assessing most common risk factors
Authors: Tewari Sachchidanand , Yadav Rahul
Published: October 2022

COVID-19 as a pandemic not only shifted the focus of the healthcare system from other diseases but also affected the disease progression of infections like tuberculosis which remained a leading killer in the past worldwide. COVID-19 itself is said to reactivate latent tuberculosis as shown in animal experiments. Immunomodulators such as corticosteroids and tocilizumab which are being used for covid treatment even further predisposes patients to tuberculosis reactivation and increased progression of the disease. Diabetes is already known to be a risk factor for tuberculosis reactivation and impact tuberculosis progression and worsen the situation. The exact mechanism of interaction of covid-19 and tuberculosis and their effect on each other remains unknown. Considering high prevalence of tuberculosis and the current scenario of covid-19 in world, there is need to study the impact of covid-19 infection on tuberculosis progression or reactivation and commonly associated risk factors. We conducted a systematic search of the online databases to collect data of patients who had tuberculosis reactivation or increased progression of disease after covid-19 infection. Data of a total of 18 patients was retrieved and used for the syntheses of the study. Diabetes was present in 50% of the patients. 55.5% patients were administered corticosteroids for covid-19 treatment later presenting with tuberculosis. Tocilizumab however was administered to 22.2% patients who also received corticosteroids. 27.7% patients suffered tuberculosis reactivation after covid-19 infection without history of diabetes and corticosteroid or tocilizumab administration. None of the patients were reported to have HIV infection. Major risk factors present in patients included corticosteroid administration and diabetes. However, tuberculosis reactivation was seen even in absence of these factors indicating that covid-19 infection may itself be responsible for tuberculosis reactivation. The exact mechanism however remains unknown and further clinical studies are needed to know the same.
A detailed overview of the patent system
Authors: Kodilkar Archana D.
Published: October 2022

The roots of today’s solid patent system are from the ancient trade system, the introduction, and the evolvement of different intellectual properties. Various international legislations, collaborations, and treaties, as well as the introduction of various acts, rules, and amendments, are responsible for the management and growth of the recent patent system. Novelty, utility, and non-obviousness are the basic patentability criteria. The Indian patent act also defines things that are not inventions under section 3 of the Indian patent act as “statutory subject matter”. The patent system working is described under patent prosecution (filing, publication, examination, opposition) sequentially. “Patent co-operation treaty” (PCT) introduced by the “World intellectual property organization” provides a most effective and economical way of patent application in multiple countries through a single filed application. A general overview of a patent application, drafting of claims, patent analysis, invalidation of patents, Infringement of patents, non-infringing activities, prosecution history estoppel, and remedies under the jurisdiction, are also described hereunder. At present, the number of patent applications filed in India is continuously increasing. Indian patent office is becoming one of the designated search authorities under the PCT. General awareness about patents and intellectual property in all sectors can be improved further.
Immunophenotype and genetic risk scores to improve autoantibody negative type 1 diabetes classification: study protocol
Authors: Patel Shivani K. , Ma Cindy S. , Bell Kirstine J. , Oram Richard , Hagopian William A. , Fourlanos Spiros , Greenfield Jerry R.
Published: October 2022

Background: An estimated 10-30% of type 1 diabetes (T1D) individuals do not have detectable autoantibodies at diagnosis, thus are classified as “idiopathic” or “non-immune.” Given the non-pathogenic role of islet autoantibodies, the validity of excluding an immune basis for disease in such individuals needs to be questioned. The pan-autoantibody negative type 1 diabetes in adults (PANDA) study aims to characterise the immune, clinical and metabolic phenotype of autoantibody negative T1D individuals.

Methods: This is a two-part, multi-centre study which is recruiting 100 participants: autoantibody positive T1D (N=25), autoantibody negative T1D (N=25), latent autoimmune diabetes in adults (N=25) and age- and sex-matched normoglycaemic control (N=25) individuals. Study 1 involves baseline pathology collection and high dimensional immune-phenotyping using flow cytometry. DNA will be extracted from saliva samples to calculate type 1 diabetes genetic risk scores (T1DGRS). Autoantibody negative individuals will undergo monogenic diabetes testing. Study 2 is a prospective, longitudinal sub-study of study 1 participants within 5 years of diagnosis. Beta cell function will be assessed using glucagon stimulated C-peptide at 0, 9 and 18 months. The primary outcome of study 1 is to determine the phenotype of immune cells in autoantibody positive and negative T1D compared to healthy controls. Secondary outcomes of study 1 include clinical and metabolic characteristics and the T1DGRS. The primary outcome of study 2 is the rate of decline of stimulated C-peptide over time.

Conclusions: The PANDA study is the first study of its kind which aims to improve diagnosis and characterisation of autoantibody negative T1D.
An exploratory, randomised, crossover study to investigate the effect of a nicotine containing electronic cigarette on appetite in healthy adult smokers, after a period of smoking abstinence: study protocol
Authors: O’Shea Olivia K. , Green Harry J. , Philpott Helen L. , Newland Nik
Published: October 2022

Background: Many individuals continue to smoke despite the known harmful effects of cigarette smoking. Tobacco harm reduction (THR) is a public health strategy that seeks to reduce or prevent projected harm caused by cigarette smoke via encouraging smokers, who would otherwise continue to smoke, to switch to products with reduced risk profiles (such as e‑cigarettes). Research shows smoking can influence numerous physiological and psychological functions such as appetite, cognitive function and emotion. For some smokers, the loss of such effects upon cessation has been cited as an incentive to resume smoking. The effect of e‑cigarettes (and other non-combustible alternatives to cigarette smoking) on the above-described physiological and psychological functions has not been widely researched. Such information may be important for more thoroughly evaluating the proposition that smokers seeking alternatives may find e-cigarettes a satisfactory substitute for conventional cigarettes.

Methods: This randomised, partially blinded, crossover study will test the hypothesis that use of a nicotine containing e-cigarette can influence appetite to the same extent as a combustible cigarette following a period of nicotine abstinence in current smokers. Up to 40 current smokers will be recruited into the study. Enrolment started in February 2021 and the results from the study are expected in 2022.

Conclusions: The data from this study will be a valuable addition to the growing body of literature about the potential of e-cigarettes as a satisfactory and viable long-term alternative to cigarettes for existing smokers.

Trial Registration: This study is registered with the ISRCTN registry, number ISRCTN72435551.
Autoimmune hemolytic anemia: a rare case report in a post-COVID patient
Authors: Iyli Chetana M. , Navale Rakesh A.
Published: October 2022

Autoimmune hemolytic anemia (AIHA), a rare disease in pediatrics, affecting one’s own immune system, is one of the causes for the acquired hemolytic anemia. For the past two years, the COVID-19 pandemic had emerged, evolved and manifested with a wide range of symptoms causing threat to human race.  In recent times, there have been literatures focused on AIHA manifesting, with novel SARS-CoV-2 infection, or as its late sequelae (secondary). The pathophysiology causing hemolysis in SARS-CoV-2 infection remains vague making it a very rare association with COVID-19. The acute symptoms of jaundice, giddiness, shortness of breath are noted, with investigations depicting hyper-inflammatory state as a most common etio-pathogenesis. This acute presentation, at times could be fatal and make the patient refractory to steroids.  There are complications due to COVID-19 infection like pneumonia, respiratory failure, acute respiratory distress syndrome etc.,known until lately where AIHA secondary to COVID-19, a very rare phenomenon is taking the spot light. A few cases of AIHA manifestation with ongoing SARS-CoV-2 have been reported and few cases which presented as a secondary infection. Here we are presenting an extremely rare case of a 16-year-old girl, with late onset anemia, post COVID-19 infection 4 weeks back.
A study to assess the knowledge regarding bio-medical waste management among the staff nurses working in selected hospital, Siliguri
Authors: Das Mamata , Khati Prerna , Banik Rita , Bhowmik Asmita , Chakraborty Mousumi , Das Bithi , Das Puja , Bhowmick Priya , Dutta Nabhanila , Biswas Mistu , Biswas Shrabani , Barma Gargi , Begum Sukria , Bhadra Ankita , Deb Mehuli , Adhikari Jayeeta , Bairagya Gargi Das , Banik Dipanwita , Karmakar Riya , Kundu Barnali , Ghosh Nilanjana , Ghosh Rita
Published: October 2022

Background: The prevalence of diabetes mellitus, is a major health concern that affects people around the world, and is increasing yearly. When blood glucose levels go below normal, a condition known as hypoglycemia, an immediate consequence of diabetes mellitus, occurs. The International Diabetes Federation reported that there were 451 million diabetics globally in 2017 and by 2045, it is anticipated that there will be 693 million. The objective of this study was to assess the level of knowledge of diabetic patient regarding hypoglycaemia and to find out the association between the levels of knowledge of diabetic patient on hypoglycaemia with their selected demographic variable.Methods: A descriptive cross-sectional study, was carried out in the month of June 2022. A semi-structured questionnaire was used to interview 100 study participants who were diabetes patients who had been admitted to the medical ward and who had visited the endocrinology outpatient department.Results: 52% of the samples had fair knowledge on hypoglycemia, while 23% of them had poor knowledge. Demographic variable such as age, income, treatment, frequency of taking medicine, experience of symptoms of hypoglycemia and dietary habit were statistically significant with the level of knowledge, p<0.05.Conclusions: The study's findings highlighted the fact that most diabetes mellitus patients had a fair understanding of hypoglycemia. The health care personnel should also take time and efforts to educate patients about the sign of hypoglycemia. So that hypoglycemic episodes and morbidity could be reduced or prevented at primordial level.
A 3-month-old child with miliary tuberculosis: a case report
Authors: Primanelza Dewi Hanifa , Tangguh Leonard , Mansyoer Riza
Published: October 2022

Miliary tuberculosis (TB) is a severe form of disseminated TB that could be fatal without treatment. It remains a significant health problem in endemic countries such as Indonesia. A-3-month-old child was admitted to the hospital with chief complain of shortness of breath, cough, and intermittent low-grade fever. Significant clinical findings were lack of weight gain, previous contact with confirmed cases of TB, and severe malnutrition. Significant laboratory findings were anemia, elevated CRP, and hypoalbuminemia. Radiological findings were suggestive of miliary TB with bilateral diffuse reticulonodular lung lesion on chest CT-scan. Diagnosis of miliary TB is difficult because of nonspecific, atypical symptoms and varied clinical signs. It is needed multiple diagnostic approach, especially for children. Miliary TB remain to be a difficult case that require an early intervention despite difficulties in its diagnosis, to prevent morbidity and mortality of patient.
A case of pituitary adenoma presenting with normal hormone levels
Authors: Surya G. S. Sanjay , Venugopalan Priya , Hanumanram Gowtham , Mithra Deepthi
Published: October 2022

We report a case of pituitary adenoma with normal hormone levels in a 34-year-old female. She presented to OP with headache, milky discharge from nipples and secondary amenorrhea with transient loss of vision. Patient had hyperprolactinemia with normal levels of all other pituitary hormones. MRI revealed space occupying lesion in sellar and suprasellar region. Neurological consultation suggested Rathke’s cyst/ craniopharyngioma/ macroadenoma. Excised lesion was diagnosed as pituitary adenoma during histopathological analysis.
Unravelling features in post COVID mucormycosis: case series with review of literature
Authors: Amaran E. G. Yog Naag , Puranik Surekha R. , Puranik Rudrayya S. , Ramdurg Praveenkumar , Srinivas Naveen , Ramesh Saahil
Published: October 2022

In the midst of the severe acute respiratory syndrome coronavirus 2 (SARS COV-2) pandemic, the victims are acquiring secondary infections like mucormycosis. Rhinocerebral mucormycosis (ROCM), is the most prevalent form and is an invasive, opportunistic fungal infection that typically affects immunocompromised patients. It exhibits a pronounced propensity to invade blood arteries, resulting in tissue thrombosis, necrosis, and infarction. Early conventional and advanced medical imaging like computed tomography (CT) and magnetic resonance imaging (MRI) is helpful in assessing the extent of involvement of this lethal disease which requires prompt and aggressive treatment. Despite of aggressive therapy, which includes disfiguring surgical debridement and frequently adjunctive toxic antifungal therapy, the overall mortality rate is high. The prime objective of present study focuses upon, unravelling the aberrant imaging presentations along with the detailed discussion about existing common features. The current study presents, a case series of 15 patients of rhino-orbital-cerebral mucormycosis (ROCM) including clinical data; common radiographic features like sinusitis, bony erosions, and soft tissue involvement also there were few uncommon features illustrated while evaluating the radiographic imaging. All patients underwent chair side and histopathological investigations. Appropriate treatment modalities were enrolled followed by rehabilitation of the defects after a thorough follow-up over an interval of 6 months. A thorough examination of the imaging findings is necessary since the aggressive nature of the infection can involve any parts of head and neck region illustrating few rare presentations involving uncommon sites. Radiologists must be aware of these unravelling radiographic features to know the precise extension of the infection.

 
Treatment of anosmia caused by COVID-19: case report
Authors: De Godoy Jose M. P. , De Godoy Livia M. P. , De Godoy Henrique J. P. , G. Godoy Maria De F.
Published: October 2022

The aim of the present study was to report the reversal of anosmia within minutes in a patient with a one-month history of COVID-19. Self-reported olfactory and taste (sweet, sour, bitter, and salty) disorders and anosmia are common in patients having had COVID-19. However, there is no specific treatment described in the literature. The present study reports a case of a 23-year-old patient with a one-month history of COVID-19 and anosmia who experienced an immediate improvement in symptoms with the use of cervical and facial lymphatic therapy.
Protección social y pobreza en América Latina y el Caribe: las claves de la región
Authors: Stampini Marco , Bosch Mariano
Published: October 2022

Este documento, basado en el Documento de Marco Sectorial de Protección Social y Pobreza, tiene el propósito de mostrar el estado actual de la protección social en América Latina y el Caribe. Para ello, se analiza tanto el contexto de la región como las acciones clave emprendidas por los países en tres ámbitos específicos de acción: apoyo al ingreso de los hogares en condición de pobreza o vulnerabilidad, atención a la dependencia funcional de las personas mayores, y atención e inclusión de las personas con discapacidad. En materia de pobreza y desigualdad, los indicadores en América Latina y el Caribe quedaron estancados a partir de 2016 tras más de una década de mejora, y acusan desde 2020 el impacto de la pandemia del COVID-19. La crisis socioeconómica sumió en la pobreza a millones de personas de la clase media emergente y puso de relieve las limitaciones de los sistemas de protección social regionales.
Strah pred digitalizacijo
Authors: Šajt Duh Nina , Bračič Lana
Published: October 2022

Podatki iz raziskav preteklih let kažejo pesimistične podatke o uporabi digitalnih tehnologij med starejšimi. Leta 2008 okoli 95 % starejših odraslih (oseb nad 65 let) ni še nikoli uporabljalo interneta. Leta 2021 smo sicer zabeležili 68 % starejših odraslih, ki so že uporabljali internet, a še vedno le 48 % takšnih, ki internet uporabljajo redno. Tako pretekli kot tudi nedavni rezultati pričajo o neprilagojenosti digitalizacije za starejše odrasle. Nekatere digitalne tehnologije so zanje neustrezno oblikovane, prav tako pa se lahko soočajo z neznanjem glede njihove uporabe. Tako med njimi kot tudi nekoliko mlajšimi osebami se lahko pojavi strah pred digitalizacijo. Vzroke lahko iščemo v pomanjkanju informacij o digitalizaciji, strahu pred izgubo delovnega mesta, mnenju, da lahko digitalizacija povzroča razčlovečenje ipd. Za takšne osebe je treba ustrezno poskrbeti, na primer s prilagoditvijo digitalnih tehnologij in prilagojenimi izobraževanji o njihovi uporabi. Pomembno je, da jim podamo dovolj informacij o digitalizaciji, te pa prilagodimo tudi vzrokom njihovega strahu pred njo. Predvsem pa je pomembno zavedanje, da lahko digitalizacija izboljša naša življenja le z vključevanjem vseh deležnikov v ta proces.
Informatizacija projektnega poslovanja
Authors: Falež Luka , Dogša Matej , Pastirk Gal
Published: October 2022

Globalna družba se giblje v smeri digitalizacije poslovnega in vsakdanjega življenja. Digitalizacija vsakodnevnih dejavnosti prinaša nove koristnosti in ugodnosti za posameznika, kot tudi za gospodarstvo. V tem poglavju se osredotočamo na pomembnost digitalizacije v podjetju Talum d.d. in to, kako lahko s pomočjo digitalne tehnologije v okviru določenega programskega okolja podjetju omogočimo notranjeizvajalsko konkurenčno prednost pri optimizaciji njegovih poslovnih statistik in projektnega upravljanja. Za vzpostavitev sistema za poslovno statistiko se podjetja načeloma odločajo za uporabo programskega jezika SQL, ki ga omogoča več aplikativnih vmesnikov. Za vzpostavitev informacijskega sistema oziroma projektnega informacijskega sistema pa imajo podjetja na voljo več možnosti. To lahko naredijo z razvojem lastne programske opreme, z naročilom po meri prilagojene programske opreme ali z uporabo že obstoječega orodja, ki bo omogočalo kakovostno distribucijo projektnih informacij in dokumentacije pomembnim deležnikom v enkratnem ali kontinuiranem procesu. V poglavju smo se osredotočili na že obstoječa orodja in jih integrirali v en skupni sistem, ki bo podjetju omogočal lažje in učinkovitejše vodenje projektov.
Inclusion of Dark Heritage in the Contemporary Tourist Offer of the City of Maribor
Authors: Raušl Katja , Prevolšek Boris , Rangus Marjetka
Published: October 2022

Dark tourism is a form of tourism based on visiting places with a connection to death, violence, suffering, or natural disasters. Human fascination with death is not new, it has been present and observable since ancient times. Nowadays, numerous products of the entertainment industry rely on the theme of death as a driving force of humanity. In terms of modern dark tourism, we discuss a wide spectrum of motives behind this, which primarily come from a desire to encounter death, either staged or from a personal standpoint. In this research, we analysed how dark tourism developed through time and across the world, its role in the tourism offers of Slovenia, and what is the perception of dark tourism in the city of Maribor. Our focus is on several gruesome events that took place over the centuries of Maribor's rich history. In this case study, we analyse the stories based on these events, evaluate the spectrum of dark heritage according to theoretical models and suggest the development of new tourism products.
Rural Olympiads as Promoters of Old Folk Sports and Games
Authors: Ćurčić Nevena , Bjeljac Željko , Brankov Jovana
Published: October 2022

Traditional sports and games represent the folk tradition and culture of certain regions, part of the people’s intangible cultural heritage. Numerous traditional sports and games have been preserved in ex-Yugoslav republics, which are most often affirmed through village Olympiads and competitions in order to keep them from being forgotten. The aim of the study is to determine the content and program of rural Olympiads in ex-Yugoslav republics, the extent to which traditional sports and games are present, and the extent to which some modern sports are included. Also, the study focused on the impact of rural Olympiads on local communities and on the interaction between hosts and guests. The methodology used in the paper refers to field research (interview, observation), and document analysis, as well as the use of different data sources to validate and crosscheck findings. The results of the research indicate the presence of a large number of games of different character in the countries formed in Yugoslavia, as well as a large number of the same or similar games that arose more as a result of certain geographical and social conditions, and less as a feature of individual peoples.
Most Prominent Topics in Wellness Tourism Research: Topic Modelling Analysis
Authors: Zečević Mila , Rančić Demir Milica
Published: October 2022

This paper presents a brief overview of the development of the wellness tourism literature. In addition, an analysis and presentation of the topics that appear within this literature field are given. The purpose of this research was to point out the relevant topics that have attracted research efforts over time. In order to detect these topics, we have selected wellness tourism literature articles from Web of Science. Our analysis used topic modelling tools using a machine learning algorithm in Python. The results imply the distinction between two main research topics within wellness tourism literature – wellness and health and medical research. Such differentiation also matches the development of the wellness tourism research field itself.
When Wine Meets Generation Z
Authors: Petek Vita , Rangus Marjetka
Published: October 2022

Generation Z refers to people born in the 90s and raised in the 2000s. They have several nicknames, for example Generation 2020, the Internet Generation, Digital Natives, Screensters, and Zeds. This generation is technologically smarter than the others are and prefers to communicate via social networks. This study is about the relationship between Generation Z and wine consumption. An online survey among students was conducted to achieve this aim. The study was conducted in November and December 2020, in several Central European countries among 123 students aged 18–15 years. The results showed that the majority of respondents consider their knowledge of wines to be mediocre. Most respondents drink wine several times a month and prefer white wine. They also like to drink pure wine or wine with sweet drinks, and, when selecting a bottle of wine, taste, smell, and price are the most important factors. More than 50% of respondents buy wine at supermarkets and only 36% in wineries or wine shops. Generation Z has just begun to participate in wine tourism. As a result, their knowledge will be further upgraded and their opinions will change over the years.
علم البلاغة كمدخل في تعليم اللغة العربية في اندونيسيا
Authors: Z Edy Murdani , Mardiyah Tika
Published: October 2022

Linguistic studies in language teaching do not get a dominant place, because the relationship between the two is not direct. Even if we look further, we find that what is taught can be said directly proportional to the meaning of the language itself, which is nothing but the study of linguistics as described by linguists. In the development that occurred, various theories were used in studying the phenomenon of language, one of which was the implicature theory. This theory requires that language be seen from its effects, so that words are arranged and spoken with the aim of giving implications for listeners. More than that, balagah in Arabic studies is wider in scope, because it requires context in speaking, who is the other person, to the choice of words and sentence phrases. In this case, balagah is a good internal approach in compiling, to developing teaching materials in teaching Arabic. With a strict approach, it is hoped that the language taught is actually used and adapted to the situation of students and teachers as part of the community members who use the language and who carry out the learning and teaching process.
Narración y presentación del discurso en un corpus de narraciones elicitadas
Authors: Serrano Jonathan , Alarcón Neve Luisa Josefina
Published: October 2022

El estudio de la presentación del discurso en la narración infantil se ha limitado al análisis de la cita directa e indirecta (discurso referido). Por eso no se han considerado otras estructuras útiles para contar y presentar el habla, el pensamiento y la escritura. Este trabajo tiene como objetivo dar cuenta de esa diversidad, así como mostrar la  de un modelo de análisis estilístico-literario de prosa narrativa de ficción a un corpus elicitado constituido por 20 producciones narrativas en español de jóvenes escolarizados, generadas mediante una tarea de recuento guiado. Los resultados muestran cómo se manifiestan las distintas estructuras en las producciones analizadas y se determina la aplicabilidad del modelo para el estudio estilístico de corpus elicitados. Este análisis supone una forma más amplia de observar la narración y la presentación del discurso y, con ello, el desarrollo del lenguaje.
Les marionnettes: une stratégie pour développer l’expression orale en français
Authors: Pachón Achury Vitalia , Camargo Vargas Diego Mauricio , Castro Herrera Angela Rocío
Published: October 2022

L’objectif de cet article est de présenter les résultats d’un projet de recherche, dans le cadre d’une recherche-action, réalisé dans le but d’explorer comment l’utilisation des marionnettes influence le développement de l’expression orale en FLE chez les élèves de CE1 d’une école privée à  Tunja. Cette étude a émergé d’un diagnostic réalisé précédemment, où la nécessité de travailler l’expression orale a été mise en évidence. Une série d’ateliers de langue a permis de créer une interaction entre la marionnette et les étudiants. Pour la collecte des données, ont été utilisés trois outils : un journal de terrain, un portfolio et une vidéo finale. L'analyse des données a permis de trouver l'effet favorable des marionnettes sur une meilleure utilisation du lexique, des phrases courtes faisant des interactions simples répondant et posant des questions, leur permettant de s'exprimer avec plus de sécurité et de confiance. En plus, les élèves ont fabriqué leurs propres marionnettes et ont appris à les jouer. Enfin, on discute des effets de la marionnette chez les étudiants comme outil pour développer leur expression orale.
Obrazy czarnoskórych bohaterów w polskim kinie popularnym
Authors: Wąsik Przemysław
Published: October 2022

The purpose of this paper is to describe the ways in which the image of black characters is constructed in Polish-produced films. The text also seeks to demonstrate that in numerous cases, the method of depicting representatives of the described group is racist in its nature. The introduction presents the social and cultural perception of black people in Poland. The next part of the study analyzes individual film examples in which the creators portrayed black characters using one of the two dominants identified by the research: exoticism or comedy. By showing various images in a chronological order, the text emphasizes how the perception of black people has changed in Polish society.
Prehistoria nowych mediów w wersji krajowej (uwagi na marginesie lektury monografii Piotra Sitarskiego, Marii B. Gardy i Krzysztofa Jajki „Nowe media” w PRL)
Authors: Mazurkiewicz Adam
Published: October 2022

The article presents the monograph by Piotr Sitarski, Maria B. Garda, and Krzysztof Jajko Nowe media w PRL [New Media in the Polish People’s Republic]. The authors of the book presented how technological development was assimilated by society in the final stage of the existence of the Polish People’s Republic. Individual chapters describe the process of social assimilation of video, microcomputers, and satellite television in Poland. Referring to social history, the authors show the beginnings of the Polish digital society in the 1980s. They do this using modern methodologies from history of technology, social history, and oral history. The aim of the article is to show the processes discussed in the book against the background of social and political changes of the epoch. The documents cited (Uchwała generalna VI Kongresu Techników Polskich [Resolution of the VI Congress of Polish Technicians]) and events (Rok Nauki Polskiej [Year of Polish Science], II Kongres Nauki [II Congress of Science]) allow us to see the links between the modernization of the Polish and communist propaganda. The technology was aimed to certify the strength of the socialist system.
Merits of Fantastic Literature: A Proposal for Theoretical Framework
Authors: Trębicki Grzegorz
Published: October 2022

The paper attempts to set ground for a comprehensive debate on the merits of non-mimetic (fantastic) literature, tentatively proposing a system of four basic merits — the entertaining/fabulative, the emotional-cognitive, the speculative/extrapolative, and the aesthetic. These merits can also be alternatively viewed as narrative functions, precisely defined presuppositions, agreements between the implied reader and writer as to what literary gratifications are to be expected by the reader from the reading experience. They constitute structural dominants which are well manifested in the texts themselves. The author’s proposals should be read merely as certain initial approximations, albeit hopefully useful ones, capable of inspiring further debate.
Estado de mal convulsivo. Aspectos fisiopatológicos e clínicos.
Authors: Bentes Carla C , Pimentel José G
Published: October 2022

Convulsive status epilepticus (CSE) is a medical emergency with a prognosis associated to its duration, aetiology and patient age. On account of the absence of a satisfactory definition and of its clinical and electroencephalographical dynamic temporal evolution, recognition of this entity is a major clinical problem. Only the early recognition of CSE allows an urgent treatment, the reason why it should be adopted the following practical definition: 5 min or more of continuous seizures or two or more seizures without regain of consciousness between them. The treatment should be immediately initiated whenever a patient has a convulsion that persists more than 5 min, has a second seizure in the posictal period, or experience a generalized tonic-clonic convulsion at the time of arrival in the emergency department. The typical temporal evolution of CSE affects its prognosis since subtil SE is more refractory to treatment than evident SE. The monitoring of any kind of treatment protocol should have not only a careful clinical observation but also an EEG continuous record.
Convulsões Neonatais numa Unidade de Cuidados Intensivos Neonatais Terciária
Authors: Lopes Andreia , Vilan Ana , Guedes Maria Beatriz , Guimarães Hercília
Published: October 2022

Introdução: A ocorrência de crises convulsivas é frequente no período neonatal. Estes episódios podem ser idiopáticos, motivadospor patologia orgânica cerebral ou por distúrbios metabólicos.Objectivo: Avaliação do diagnóstico etiológico e evolução clínica dos recém-nascidos admitidos numa unidade de cuidados intensivosneonatais terciária com convulsões neonatais.Materiais e Métodos: Análise retrospectiva dos processos clínicos dos recém-nascidos com convulsões neonatais, durante um períodode oito anos.Resultados: Registaram-se 91 casos de recém-nascidos com crises convulsivas. Setenta e nove (86,8%) doentes receberam medicaçãoanticonvulsivante durante a crise. Estudos imagiológicos e/ou neurofisiológicos foram realizados na maioria dos recém-nascidos(86,8%). Foi identificada a etiologia das convulsões em 51,6% dos 91 casos estudados, sendo as situações mais frequentes a hemorragiacerebral (11 casos) a encefalopatia hipóxico-isquémica (10 casos) e as anomalias electrolíticas (7 casos). A taxa de mortalidadefoi de 16,5%. Dos recém-nascidos seguidos no nosso hospital verificou-se que 70,2% tiveram um desenvolvimento psicomotor normalmas em 10,6% foram detectadas anomalias graves do desenvolvimento psicomotor, incluindo paralisia cerebral.Conclusões: A existência de anomalias na ecografia transfontanelar e no electroencefalograma esteve relacionada com a evoluçãoclínica, pelo que continuam a ser os exames de eleição na abordagem inicial desta patologia.
Nódulo da Irmã Maria José
Authors: Esperto Helder , Canha Catarina , Meira Elisa
Published: October 2022

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Nov pristop k preventivi v odnosih: Predstavitev metode Rebuild-Relationship Building Dance(R)
Authors: Erdőfi Anna
Published: October 2022

Visok delež ločitev po vsem svetu opozarja na potrebo po krepitvi in ohranjanju kakovosti partnerskih odnosov in zakonskih zvez, vendar v terapiji težavo pogosto povzroča to, da partnerja pomoč ob težavah pričneta iskati prepozno. Zato je pomembno pozornosti posvetiti tudi možnostim preventivnega dela v odnosih. Programi, namenjeni gradnji odnosa, ki so bili razviti v preventivne namene, imajo številne prednosti, a so jih raziskovalci pogosto kritizirali. Odgovor na kritike bi lahko bil tudi novo razvit pristop za praktično psihoedukacijo Rebuild-Relationship Building Dance(R), ki za krepitev odnosov uporablja dvoranski ples. Cilj študije je raziskati učinkovitost metode s kvantitativnim pristopom. Dve leti trajajoča študija je vključevala partnerje, ki so se pripravljali na sklenitev zakonske zveze. Raziskovalna skupina (N = 64) je trikrat izpolnila sklop vprašalnikov o kakovosti partnerske zveze (BFI, RAS, DCI, FACES IV/komunikacija, PSI, RSES, PAIR), kontrolna skupina (N = 38) pa je te vprašalnike izpolnila dvakrat. Statistične analize so pod-prle pozitivne učinke metode na partnerske zveze na področjih samozavesti, zadovoljstva z odnosom, komunikacije, soočanja s konflikti, intimnosti, spolnosti in skrbi za partnera. Med rezultati testov kontrolne skupine v obeh časovnih točk ni bilo (pozitivne) razlike, v osmih mesecih pa je bilo moč opaziti celo poslabšanje pri nekaterih spremenljivkah (spolnost, komunikacija, zadovoljstvo z odnosom). Rezultati kaže-jo, da metoda predstavlja novo in praktično alternativo za preventivno dejavnost v partnerskih zvezah, ki lahko dopolnjuje klasične terapevtske metode.
Etnomatemática, interculturalidade e educação infantil: a formação continuada de professoras em um curso de extensão
Authors: Santino Fernando Schlindwein , Ciríaco Klinger Teodoro
Published: October 2022

Relatamos resultados de uma investigação que teve como base analisar as contribuições de uma ação de extensão à formação continuada de professor@s. Objetivou-se compreender quais são os impactos deste curso à promoção de práticas pedagógicas que valorizem a Interculturalidade na perspectiva da Etnomatemática. Elegeu-se como referencial teórico, documentos e produções científicas sobre as temáticas-chaves da discussão em uma ampla relação com a cultura indígena. Para a produção dos dados, adotou-se uma descrição e análise do percurso vivenciado pelo grupo de cursistas, bem como de um roteiro de entrevista semiestruturado realizado com duas colaboradoras. As impressões da realidade educacional evidenciam que existem algumas barreiras para que o atendimento à infância indígena se faça de forma mais inclusiva, uma vez que, a cultura escolar ainda insiste em abordagens estereotipadas sobre os modos de produção e de vida das etnias
Panorama da língua Kambeba/Omágua em Manaus/Amazonas: possibilidades de retomada, manutenção e fortalecimento linguístico e cultural
Authors: Oliveira Cila Mariá Fonseca de , Cruz Mônica Cidele da
Published: October 2022

O propósito deste artigo consiste em apresentar brevemente o panorama atual da língua Kambeba/Omágua (Tupi-Guarani), por meio da apresentação de exemplos de ações voltadas para a retomada, manutenção e fortalecimento desta língua falada na comunidade Três Unidos, em Manaus/Amazonas. Desta forma, este trabalho objetiva uma leve reflexão acerca da necessidade e importância da documentação e da descrição de línguas indígenas como modelo sócio-linguístico-educacional. Por fim, este estudo se mostra relevante para outras pesquisas, pois apresenta um início de uma ação voltada para as comunidades indígenas que estão ou estarão interessadas na revitalização de línguas ameaçadas de extinção. 
Palavras-chave: Kambeba; Língua; Retomada; Manutenção; Fortalecimento
CONHECENDO A RESTINGA DO PARQUE ESTADUAL DA SERRA DO TABULEIRO: A EDUCAÇÃO GEOGRÁFICA EM ESPAÇOS NÃO FORMAIS E A PRODUÇÃO DE UM GUIA ETNOBOTÂNICO
Authors: CAROLINA SCHUHLI ANA , DE HARO THOMÉ ISADORA , NUNES CHAVES ANA PAULA
Published: October 2022

O presente artigo tem por finalidade apresentar as experiências vivenciadas durante o Estágio Curricular Supervisionado em Geografia III, da Universidade do Estado de Santa Catarina (UDESC), por meio da elaboração de um guia etnobotânico, material didático proposto como atividade avaliativa da disciplina de estágio realizado no semestre 2022.01. O curso de Geografia da UDESC permite que as vivências de estágio ocorram tanto em espaços formais quanto em espaços não formais de educação e tem parceria como campo de estágio com a unidade de conservação de proteção integral, o Parque Estadual da Serra do Tabuleiro (PAEST), como um espaço possível para que a educação geográfica possa acontecer. O PAEST representa a maior unidade de conservação do estado de Santa Catarina, está totalmente inserido no bioma da Mata Atlântica e sua rica biodiversidade de espaços dá a ele visibilidade para ações educativas. Um desses espaços é a Restinga, ecossistema  que foi estudado para a seleção de espécies significativas para compor  o guia botânico, o qual explorou tanto o ambiente onde a espécie se distribui, como a sua relevância natural e sociocultural
Is Sensation-Seeking Always Bad? The Role of Sensation-Seeking in Predicting Individual Work Role Performance
Authors: Sekar Lelyana Margaretha Langen , Ervina Siregar Rury , Dwi Mustika Martina
Published: October 2022

Sensation-seeking can be an outcome predictor in an organization when expressed through several social cognitive variables, such as emotional intelligence. Thus, the behavior generated by sensation-seeking can be more functional. The purpose of this study is to identify whether sensation-seeking can be expressed through emotional intelligence to predict individual performance. This study uses a quantitative design with a correlational strategy. The study participants were 167 Indonesian employees from three banking, oil and gas, and mining industries who filled out a questionnaire investigating their sensation-seeking, emotional intelligence, and individual performance. The questionnaires used Work Role Performance Scale and Learning Style Profiler. Data analysis was done by mediation process from Hayes. The results show that sensation-seeking and emotional intelligence directly predicts individual performance. However, indirect effect analysis proves that emotional intelligence cannot express sensation-seeking to predict individual performance. Thus, people who have high level of sensation-seeking not always bad because they can be an active learner also improve their work role performance in organization.
Assessment Of 3D Printed Polycaprolactone, Hydroxyapatite Nanoparticles and Polyethylene Glycol Diacrylate Scaffolds for Bone Regeneration
Authors: Sousa Ana Catarina , Biscaia Sara , Alvites Rui , Branquinho Mariana , Lopes Bruna , Sousa Patrícia , Valente Joana , Franco Margarida , Santos José Domingos , Mendonça Carla , Atayde Luís , Alves Nuno , Maurício Ana Colette
Published: October 2022

Notwithstanding the advances achieved in the last decades in the field of synthetic bone substitutes, the development of biodegradable 3D scaffolds with ideal mechanical and biological properties remains an unattained challenge. In this work, a novel approach is explored to produce synthetic bone grafts mimicking the complex bone structure using additive manufacturing. For the first time, scaffolds were produced, using an extrusion technique, composed of a thermoplastic polymer, polycaprolactone (PCL), hydroxyapatite nanoparticles (HANp), and polyethylene glycol diacrylate (PEGDA). These scaffolds were further compared with two groups of scaffolds: one composed of PCL and another of PCL and HANp. After production, optimisation and characterisation of these scaffolds, an in vitro evaluation was performed using human dental pulp stem/stromal cells (hDPSCs). Through the findings it was possible to conclude that PEGDA scaffolds were successfully produced presenting networks of interconnected channels, presenting hydrophilic properties (15.15 4.06°), adequate mechanical performance (10.41MPa 0.934), and allowing a cell viability significantly superior to the other groups analysed. To conclude, findings in this study demonstrated that PCL, HANp and PEGDA scaffolds may have promising effects on bone regeneration and might open new insights for 3D tissue substitutes.
The Role of Microplastics on Marine Pathogen Transmission: Retrospective Regression Analysis, Experimental Design, and Disease Modelling
Authors: Bidegain Gorka , Sestelo Marta , Luque Patricia L , Uriarte Ibon , Iriarte Arantza , Villate Fernando
Published: October 2022

Marine wildlife and aquaculture species can accumulate large amounts of microplastic particles (<1 mm), threatening the health of marine populations and ecosystems and posing a risk to food safety and human health. The uptake of chemicals from microplastics seems to decrease the immune capacity of bivalves and corals to fight pathogenic bacteria, thereby increasing their vulnerability to disease. Moreover, major pathogens of bivalves, fish, and humans, including several Vibrio species, have been shown to be specifically enriched in the microbial communities adhered to marine microplastic debris (MMD). Microplastics can therefore serve as an important vector for and regulator of pathogen transmission and disease dynamics. Here, we outline a theoretical, three-perspective approach for studying the relationship between MMD and disease. First, we provide a framework for retrospective analysis of MMD and pathogen loads in marine animal tissues to assess the relationships between them, their bioaccumulation over time, and their relationship to other environmental variables. The results from such an analysis can be used to decide whether a compound or pathogen should be considered an emerging substance or organism. Second, we describe an experimental design for testing the effect of a variety of microplastics on in vivo pathogen removal (i.e., the phagocytic activity of hemocytes) and infection intensity in two study model species (oysters and zebrafish). Finally, we create a theoretical susceptible-infected microplastic particle and pathogen transmission model for bivalves and fish. Overall, the experiments and models we propose will pave the way for future research designed to assess the role of MMD as a vector for marine and human pathogens. This multi-faceted approach needs to be an urgent priority of the EU Strategic Research Innovation Agenda for addressing marine disease challenges related to MMD.
The consistency of diagnostic findings among lacrimal syringing, dacryocystography, and dacryoendoscopy in lacrimal drainage system obstruction
Authors: Nakamura Jutaro , Kamao Tomoyuki , Mitani Arisa , Mizuki Nobuhisa , Shiraishi Atsushi
Published: October 2022

Aim
To investigate the consistency of diagnostic findings in lacrimal syringing, dacryocystography (DCG), and dacryoendoscopy in the obstruction of the lacrimal drainage system (LDS).
Methods
We retrospectively examined 113 patients (211 LDS) who underwent syringing, DCG, and dacryoendoscopy to evaluate LDS obstruction. LDS obstruction was compared by classifying grade and site into three levels, respectively. The diagnostic consistency between the examinations was assessed by determining the weighted kappa value.
Results
A total of 25 male (49 LDS) and 88 female patients (162 LDS) were included in this study. Obstructions were observed in 77.4%, 60.0%, and 81.3% of LDS by syringing, DCG, and dacryoendoscopy, respectively. Regarding the agreement in obstruction grade, Cohen’s kappa value for DCG and dacryoendoscopy was 0.65 (95% confidence interval [CI]: 0.56–0.74). Although DCG diagnosed as patent in 38.4% of all LDS, 47.9% of them revealed partial or complete obstruction by dacryoendoscopy. Meanwhile, DCG and dacryoendoscopy showed consistency in the obstruction site in 77.9% of LDS. When discrepancies were observed between syringing and dacryoendoscopy in detecting the obstruction site, the combined diagnosis of syringing and DCG reached dacryoendoscopy findings at the 99% level.
Conclusions
“Substantial” agreements were found among the three examinations in diagnosing obstruction grade and site (Fleiss κ > 0.6 for both). Then, the highest agreement was observed between syringing and dacryoendoscopy in determining the obstruction site (κ = 0.7). The lowest agreements were observed between syringing and DCG in diagnosing the obstruction grade and site (κ = 0.55 for both).