bluuebunny/crossref_metadata_2025 huggingface dataset:
An Open-Source System for Generating and Computer Grading Traditional Non-Coding Assignments
Authors: Lapeña-Mañero Pablo , García-Casuso Carmen , Montenegro-Cooper José Miguel , King Robert W. , Behrens Edwin M.
Published: March 2022

One of the most time-consuming activities in higher education is reviewing and grading student evaluations. Rapid and effective feedback of evaluations, along with an appropriate assessment strategy, can significantly improve students’ performance. Furthermore, academic dishonesty is a major issue in higher education that has been aggravated by the limitations derived from the COVID-19 pandemic. One of the possible ways to mitigate this issue is to give different evaluations to each student, with the negative cost of increasing reviewing time. In this work, an open-source system developed in Python to automatically create and correct evaluations is presented. Using Jupyter Notebook as the graphical user interface, the system allows the creation of individual student question sheets, with the same structure and different parameter values, to send them to students, grade them, and send the final score back to the students. The proposed system requires little programming knowledge for the instructors to use it. The system was applied in Civil Engineering and Geological Engineering programs at the Universidad Católica de la Santísima Concepción, drastically reducing grading time while improving students’ performance.
Commercial P-Channel Power VDMOSFET as X-ray Dosimeter
Authors: Ristić Goran S. , Ilić Stefan D. , Veljković Sandra , Jevtić Aleksandar S. , Dimitrijević Strahinja , Palma Alberto J. , Stanković Srboljub , Andjelković Marko S.
Published: March 2022

The possibility of using commercial p-channel power vertical double-diffused metal-oxide-semiconductor field-effect transistors (VDMOSFETs) as X-ray sensors is investigated in this case study. In this aspect, the dependence of sensitivity on both the gate voltage and the mean energy for three X-ray beams is examined. The eight gate voltages from 0 to 21 V are applied, and the dependence of the sensitivity on the gate voltage is well fitted using the proposed equation. Regarding X-ray energy, the sensitivity first increases and then decreases as a consequence of the behavior of the mass energy-absorption coefficients and is the largest for RQR8 beam. As the mass energy-absorption coefficients of SiO2 are not found in the literature, the mass energy-absorption coefficients of silicon are used. The behavior of irradiated transistors during annealing at room temperature without gate polarization is also considered.
Sustainability Development: Assessment of Selected Indicators of Sustainable Energy Development in Poland and in Selected EU Member States Prior to COVID-19 and Following the Third Wave of COVID-19
Authors: Stankowska Anna
Published: March 2022

An important question in the literature on climate change and sustainable development is the relationship between countries’ economic growth, household electricity consumption and greenhouse gas emissions. Despite the ongoing COVID-19 pandemic and related economic restrictions, sustainable economic growth remains at the forefront of the global development agenda. However, given the strong relationship between the ever increasing electricity consumption and greenhouse gas CO2 emissions, an increasing number of scientists have been questioning the feasibility of the planned emission reduction. In my research, I strove to determine whether there exists a relationship between the change in the structure of electricity consumption of households in selected EU Member States (15 countries), the impact of innovation, changes in electricity prices and economic growth, and CO2 emissions in 2007–2019, prior to the outbreak of the COVID-19 pandemic, and following its third wave (2021). The aim of the article is to propose a synthetic index to assess the degree of sustainable energy development (SISED) in selected EU countries. Multiobjective decision analysis (MODA) was applied in order to assess the sustainable energy development of the selected European countries. Research findings may contribute to both literature and practice if they are applied by individual EU countries in the process of formulating directions aimed at achieving sustainable energy development.
A Review of the Status of Fossil and Renewable Energies in Southeast Asia and Its Implications on the Decarbonization of ASEAN
Authors: Lau Hon Chung , Zhang Kai , Bokka Harsha Kumar , Ramakrishna Seeram
Published: March 2022

The ten nations of Southeast Asia, collectively known as ASEAN, emitted 1.65 Gtpa CO2 in 2020, and are among the most vulnerable nations to climate change, which is partially caused by anthropogenic CO2 emission. This paper analyzes the history of ASEAN energy consumption and CO2 emission from both fossil and renewable energies in the last two decades. The results show that ASEAN’s renewable energies resources range from low to moderate, are unevenly distributed geographically, and contributed to only 20% of total primary energy consumption (TPEC) in 2015. The dominant forms of renewable energies are hydropower, solar photovoltaic, and bioenergy. However, both hydropower and bioenergy have substantial sustainability issues. Fossil energies depend heavily on coal and oil and contribute to 80% of TPEC. More importantly, renewable energies’ contribution to TPEC has been decreasing in the last two decades, despite the increasing installation capacity. This suggests that the current rate of the addition of renewable energy capacity is inadequate to allow ASEAN to reach net-zero by 2050. Therefore, fossil energies will continue to be an important part of ASEAN’s energy mix. More tools, such as carbon capture and storage (CCS) and hydrogen, will be needed for decarbonization. CCS will be needed to decarbonize ASEAN’s fossil power and industrial plants, while blue hydrogen will be needed to decarbonize hard-to-decarbonize industrial plants. Based on recent research into regional CO2 source-sink mapping, this paper proposes six large-scale CCS projects in four countries, which can mitigate up to 300 Mtpa CO2. Furthermore, this paper identifies common pathways for ASEAN decarbonization and their policy implications.
Establishment of a Laboratory Scale Set-Up with Controlled Temperature and High Humidity to Investigate Dry Matter Losses of Wood Chips from Poplar during Storage
Authors: Hernandez-Estrada Albert , Pecenka Ralf , Dumfort Sabrina , Ascher-Jenull Judith , Lenz Hannes , Idler Christine , Hoffmann Thomas
Published: March 2022

The aim of this work was to improve the understanding of dry matter losses (DML) that occur in wood chips during the initial phase of storage in outdoor piles. For this purpose, a laboratory scale storage chamber was developed and investigated regarding its ability to recreate the conditions that chips undergo during the initial phase of outdoor storage. Three trials with poplar Max-4 (Populus maximowiczii Henry × Populus nigra L.) chips were performed for 6–10 weeks in the storage chamber under controlled temperature and assisted humidity. Two different set-ups were investigated to maintain a high relative humidity (RH) inside the storage chamber; one using water containers, and one assisted with a humidifier. Moisture content (MC) and DML of the chips were measured at different storage times to evaluate their storage behaviour in the chamber. Additionally, microbiological analyses of the culturable fraction of saproxylic microbiota were performed, with a focus on mesophilic fungi, but discriminating also xerophilic fungi, and mesophilic bacteria, with focus on actinobacteria, in two trials, to gain a view on the poplar wood chip-inhabiting microorganisms as a function of storage conditions (moisture, temperature) and time. Results show that DML up to 8.8–13.7% occurred in the chips within 6–10 storage weeks. The maximum DML were reached in the trial using the humidifier, which seemed a suitable technique to keep a high RH in the testing chamber, and thus, to analyse the wood chips in conditions comparable to those in outdoor piles during the initial storage phase.
Analyzing the Consequences of Sharing Principles on Different Economies: A Case Study of Short Rotation Coppice Poplar Wood Panel Production Value Chain
Authors: Perdomo Echenique Enrique Alejandro , Ryberg Morten , Vea Eldbjørg Blikra , Schwarzbauer Peter , Hesser Franziska
Published: March 2022

Quantifying the environmental impacts of value chains on the earth’s ecological limits is crucial to designing science-based strategies for environmental sustainability. Combining the Planetary Boundaries (PB) and Life Cycle Assessment (LCA) framework can be used to estimate if a value chain can be considered as Absolute Environmentally Sustainable (AES) in relation to the PB. One of the crucial steps in implementing the PB-LCA framework is using sharing principals to downscale the global PB to smaller scales (e.g., country) and calculate an assigned Safe Operating Space (aSOS). This study assesses the potential AES of a wood panel value chain in Austria and Slovakia to understand the consequences of applying diverse sharing principles on different economies. Two economic and one emission-based sharing principles were compared. The results show that depending on the sharing principle implemented, different conclusions on the AES and potential strategies at a value chain and national level are achieved. Economic-based sharing principles are biased to the value chain’s economical contribution. As for the emission-based approach, greater aSOS is given to systems with a higher contribution of emissions. A potential downside of either approach is that it can lead to misleading environmental strategies, such as hindering the development of less wealthy value chains and giving less incentive to improve environmental efficiency. These outcomes highlight the importance of further research into resolving the issues about just assignment of SOS. Moreover, our study contributes to the effort of making the PB-LCA framework relevant for strategic decision-making at a value chain level.
Survey on Videos Data Augmentation for Deep Learning Models
Authors: Cauli Nino , Reforgiato Recupero Diego
Published: March 2022

In most Computer Vision applications, Deep Learning models achieve state-of-the-art performances. One drawback of Deep Learning is the large amount of data needed to train the models. Unfortunately, in many applications, data are difficult or expensive to collect. Data augmentation can alleviate the problem, generating new data from a smaller initial dataset. Geometric and color space image augmentation methods can increase accuracy of Deep Learning models but are often not enough. More advanced solutions are Domain Randomization methods or the use of simulation to artificially generate the missing data. Data augmentation algorithms are usually specifically designed for single images. Most recently, Deep Learning models have been applied to the analysis of video sequences. The aim of this paper is to perform an exhaustive study of the novel techniques of video data augmentation for Deep Learning models and to point out the future directions of the research on this topic.
The Functional Relationship of Sediment Transport under Various Simulated Rainfall Conditions
Authors: Henorman Hanna Mariana , Tholibon Duratul Ain , Nujid Masyitah Md , Mokhtar Hamizah , Rahim Jamilah , Saadon Azlinda
Published: March 2022

Sediment removed in the detachment process is transported by overland flow. Previous experimental and field works studied that sediment transport is influenced by hydraulic properties of flow, physical properties of soil, and surface characteristics. Several equations in predicting sediment transport have been developed from previous research. The objective of this paper was to establish the selected parameters that contribute to the sediment transport capacity in overland flow conditions under different rainfall pattern conditions and to evaluate their significance. The establishment of independent variables was performed using the dimensional analysis approach that is Buckingham’s π theorem. The final results obtained are a series of independent parameters; the Reynolds number (Re), dimensionless rainfall parameter iLν, hydraulic characteristics QLν that related to the dependent parameters; and dimensionless sediment transport qsρv. The relationship indicates that 63.6% to 72.44% of the variance in the independent parameters is in relation to the dependent parameter. From the iteration method, the estimation of constant and regression coefficient values is presented in the form of the general formula for linear and nonlinear model equations. The linear and nonlinear model equations have the highest model accuracy of 93.1% and 81.5%, respectively. However, the nonlinear model equation has the higher discrepancy ratio of 54.9%.
Food Choice Motives and COVID-19 in Belgium
Authors: Mertens Elly , Sagastume Diana , Sorić Tamara , Brodić Ivona , Dolanc Ivan , Jonjić Antonija , Delale Eva Anđela , Mavar Mladen , Missoni Saša , Čoklo Miran , Peñalvo José L.
Published: March 2022

To investigate the main motives driving dietary intake changes potentially introduced by preventive measures to address the pandemic, an online survey, using a 36-item Food Choice Questionnaire applied for the period before (the year 2019) and during (2020–2021) the pandemic, was distributed between July and October 2021 among adult residents from Belgium. A total of 427 eligible respondents, the majority Dutch-speaking, were included for analyses. The importance of nine motives for food choices, including health, mood, convenience, sensory appeal, natural content, price, weight control, familiarity and ethical concerns, was assessed by scoring from 1 to 5, and comparing mean scores from the during period with the before period. Sensory appeal was the most important food choice motive before (mean score of 4.02 ± 0.51) and during (3.98 ± 0.48) the pandemic. Convenience and health also ranked among the main motives, with health observed to become more important during the pandemic (3.69 ± 0.60 during vs. 3.64 ± 0.59 before). Additionally, mean scores of mood (3.41 ± 0.71 vs. 3.32 ± 0.58), natural content (3.35 ± 0.84 vs. 3.26 ± 0.85) and weight control (3.33 ± 0.79 vs. 3.25 ± 0.76) were significantly higher during as compared to before. The extent of change in the level of importance for natural content was smaller with increasing age, and for health larger for urban areas, but for other motives there were no significant differences across population subgroups. Changes in the level of importance were observed in both directions, while a moderate share of respondents declared no change, suggesting some persistence of food choice motives. Further activities within public health monitoring should be considered to fully understand the COVID-19 implications on food choice motives together with people’s food behaviors and consumption.
Impact of an Omega-3-Enriched Sheep Diet on the Microbiota and Chemical Composition of Kefalograviera Cheese
Authors: Tzora Athina , Nelli Aikaterini , Voidarou Chrysoula (Chrysa) , Fotou Konstantina , Bonos Eleftherios , Rozos Georgios , Grigoriadou Katerina , Papadopoulos Panagiotis , Basdagianni Zoitsa , Giannenas Ilias , Skoufos Ioannis
Published: March 2022

Kefalograviera is a well-known hard Greek cheese. The aim of this study was to determine how milk produced from ewes fed omega-3-enriched diets could influence the microbiota as well as the chemical composition of Kefalograviera cheese. At the start of the trial, 30 dairy ewes (Lesvos and Chios crossbreed) were selected and fed a conventional diet, based on alfalfa hay, straw and concentrate feed that contained soybean meal for a period of thirty days. Then, for a period of sixty days the same ewes were fed an omega-3-enriched concentrate feed with a lower level of soybean meal that contained 10% flaxseed and 10% lupins. Milk yield was collected individually on Days 30, 60 and 90 and used to produce three different batches of Kefalograviera cheeses, at the same cheese factory, by using a traditional recipe and identical preparation conditions (pasteurization of milk, salt, rennet and culture). Sample analysis was done after six months of Kefalograviera cheese ripening. MALDI-TOF-MS (matrix-assisted laser desorption/ionization time of flight mass spectrometry) identification was performed by contrasting the samples’ mass spectra with the corresponding reference database. The correlation between the different Kefalograviera cheeses revealed the predominant species being Lactococcus lactis, Lactobacillus rhamnosus, Lactobacillus plantarum, Lactobacillus brevis, Lactobacillus paracasei, Enterococcus faecium and Enterococcus faecalis, with significant quantitative differences between the experimental groups and the controls. Pediococcus spp. was isolated only from the experimental groups’ cheeses and Staphylococcus spp. only from the controls’ cheese, suggesting—among other differences—a bacterial microbiota distinction between the groups. Moreover, increased levels of alpha-linolenic acid and total polyunsaturated omega-3 fatty acids were noted in the enriched Kefalograviera cheeses. These promising findings suggest that enriched Kefalograviera cheese could be manufactured via enriching the ewes’ diets, with potential benefits for the consumers’ health.
Dynamic Analysis and Bifurcation Study on Fractional-Order Tri-Neuron Neural Networks Incorporating Delays
Authors: Li Peiluan , Yan Jinling , Xu Changjin , Shang Youlin
Published: March 2022

In this manuscript, we principally probe into a class of fractional-order tri-neuron neural networks incorporating delays. Making use of fixed point theorem, we prove the existence and uniqueness of solution to the fractional-order tri-neuron neural networks incorporating delays. By virtue of a suitable function, we prove the uniformly boundedness of the solution to the fractional-order tri-neuron neural networks incorporating delays. With the aid of the stability theory and bifurcation knowledge of fractional-order differential equation, a new delay-independent condition to guarantee the stability and creation of Hopf bifurcation of the fractional-order tri-neuron neural networks incorporating delays is established. Taking advantage of the mixed controller that contains state feedback and parameter perturbation, the stability region and the time of onset of Hopf bifurcation of the fractional-order trineuron neural networks incorporating delays are successfully controlled. Software simulation plots are displayed to illustrate the established key results. The obtained conclusions in this article have important theoretical significance in designing and controlling neural networks.
Unnatural Cycles: Anthropogenic Disruption to Health and Planetary Functions
Authors: Gibson Gillian , Stewart Alex G.
Published: March 2022

Natural cycles underpin the very stuff of life. In this commentary we consider unnatural cycles: that is, anthropogenic activities which have a circularity, but whose nature is to have a detrimental effect on human health, exacerbating existing problems. Natural cycles have feedback loops, some of which have recently come to light, with an understanding that everything is connected in some way. In health, feedback loops are imperative in homeostatic mechanisms. However, in the unnatural cycle the feedback loops serve to reinforce (and in some cases amplify) negative problems. We offer a commentary on an unnatural cycle moving from air quality to lung function and back to air quality; we call this the lung disease unnatural cycle. We suggest where links occur, and where wider consideration of interactions between various disciplines can lead to breaking this unnatural (or vicious) cycle, changing it to a healthy cycle where individual health can be improved, along with better global scale outcomes. We suggest that many activities within this unnatural cycle occur within silos. However, the improved cycle incorporates joint activities at geological, health, and financial levels, to the mutual benefit of all, breaking the unnatural cycle and improving health, life, and financial costs.
Teaching and Learning of Clinical Competence in Ghana: Experiences of Students and Post-Registration Nurses
Authors: Salifu David Abdulai , Heymans Yolande , Christmals Christmal Dela
Published: March 2022

Despite the growing demand for competent nurses to fill the shortage gap, nursing education institutions have not always been able to equip students with the requisite clinical competence needed in the practice setting. Several studies have described the experiences of undergraduate nursing students in the clinical learning environment. No study was found on the experiences of diploma nursing students and post-registration nurses regarding the teaching and learning of clinical competence in Ghana. This study, therefore, sought to describe the experiences and perceptions of diploma nursing students and post-registration nurses regarding the teaching and learning of clinical competence in Ghana. A qualitative descriptive research design was employed in this study. Fifty-five (55) participants, comprising 40 students and 15 post-registration diploma nurses, from six research sites were recruited into focus group discussions (FGDs) using a maximum variation purposive sampling technique. A thematic framework method was used to analyze the data with the aid of ATLAS.ti software. Three themes emerged from the focus group discussions: nursing education institutional factors; clinical placement design, implementation, and system challenges; challenges of clinical teaching and learning. We conclude that the current approach to clinical nursing education, such as the overreliance on clinical placement and the use of more teacher-centered teaching approaches, are ineffective in facilitating the development of clinical competence. A review of the nursing curriculum, inculcating evidence-based simulation modalities, and an adequate investment in nursing education may be required to ensure effective nursing education in the study setting.
Differentiating Degenerative from Vascular Dementia with the Help of Optical Coherence Tomography Angiography Biomarkers
Authors: Chalkias Efthymios , Chalkias Ioannis-Nikolaos , Bakirtzis Christos , Messinis Lambros , Nasios Grigorios , Ioannidis Panagiotis , Pirounides Demetrios
Published: March 2022

Alzheimer’s disease and vascular dementia account for the majority of cases of cognitive decline in elderly people. These two main forms of dementia, under which various subtypes fall, are often overlapping and, in some cases, definitive diagnosis may only be possible post-mortem. This has implications for the quality of care and the design of individualized interventions for these patients. Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality used to visualize the retinal layers and vessels which shows encouraging results in the study of various neurological conditions, including dementia. This review aims to succinctly sum up the present state of knowledge and provide critical insight into emerging patterns of OCTA biomarker values in Alzheimer’s disease and vascular dementia. According to the current literature, vessel density seems to be a common biomarker for both forms; inner retinal layer thickness might represent a biomarker preferentially affected in degenerative dementia including Alzheimer’s, while, in contrast, the outer-layer thickness as a whole justifies attention as a potential vascular dementia biomarker. Radial peripapillary capillary density should also be further studied as a biomarker specifically linked to vascular dementia.
Gender Equality in Employment among Health Care Undergraduate Students: A Cross-Sectional Survey
Authors: Hsieh Chia-Jung , Pan Kai , Lee Hui-Chen , Shih Ya-Ling
Published: March 2022

Objectives: The purposes of this study were to predict the important variables associated with health care undergraduate students’ opinion of gender equality (GE) in employment. Design: This study adopted a cross-sectional design with multistage sampling and adhered to STROBE guidelines. Setting: From one of the universities of health care in northern Taiwan. Participants: We recruited 2855 health care students and the questionnaire response rate was 78.3%. Results: Female students in this study have a better concept of GE in employment. There was a statistically significant negative correlation between the subjects’ gendered concept of family and GE in employment. From the results of multiple linear regressions, the important and significant variables were female, sophomore students, students who were in the division of continuing college self-attitude toward gender roles, attitude toward parental expectations of gender roles, those could explain 45.3% of the variation in GE in employment. Conclusion: Students exposed to the active cultivation of GE in health education largely benefit future professional development. Establishing a GE concept on campus will help students develop their profession in the future. Encourage the school to offer at least one “gender-related” elective subject per semester, especially in the on-the-job training programs to satisfy the needs of GE education.
Effect of Seawater Irrigation on the Sugars, Organic Acids, and Volatiles in ‘Reliance’ Grape
Authors: Liu Menglong , Yu Meng , Yao Yuxin , Zhai Heng , Tang Meiling , Gao Zhen , Du Yuanpeng
Published: March 2022

Ongoing climate change in recent decades exacerbated the decline in agricultural water use, and seawater irrigation could feasibly alleviate the shortage of water resources, which restricts viticulture in some countries. However, studies on the effects of seawater irrigation on grape volatiles are limited. Herein, ‘Reliance’ grapevines were irrigated with diluted seawater (10% concentrations) in the field since the pea-size berry stage (S1), stage EL 32 (S2), and the pre-veraison period (S3) every seven days. Results showed irrigation with seawater significantly increased the sugar content and decreased the organic acids when compared with the control berries. Seawater irrigation did not induce secondary soil salinization, and it enhanced the volatiles in the fatty acid and isoprene pathways without affecting the amino acid pathway aroma. More terpenes were found in seawater-treated berries, including citronellol, β-myrcene, α-terpineol, and trans-rose oxide. Gene profiling by RT-qPCR analysis revealed that VvLOXA could be the primary gene in C6 volatile biosynthesis altered by the seawater. Moreover, seawater irrigation during the pea-size period had the best effect on fruit quality. This work adds to our understanding of the effect of seawater irrigation on grape aroma quality and provides a sufficient basis for the utilization of seawater in vineyards.
Production Methods for High Yielding Plants of Everbearing Strawberry in the Nordic Climate
Authors: Sønsteby Anita , Sadojevic Mirjana , Heide Ola M.
Published: March 2022

Environmental conditions during plant raising determine the yield potential of everbearing strawberries. We studied the effect of three rooting dates in the cultivars ‘Favori’ and ‘Murano’ in a greenhouse with 18 ℃ and 20-h long day and under outdoor conditions in Norway. The highest yield of 1.350 g/plant was obtained in ‘Favori’ plants rooted on 1 August and raised outdoors, being at level with ‘Favori’ plants produced in The Netherlands. High yields were mainly related to fruit size and less to fruit number, and determined by a complex three-factor interaction of rooting date, raising environment, and cultivar. The seasonal pattern of fruit flushes and off periods varied significantly between cultivars and treatments. The large first flush of high yielding ‘Favori’ plants was associated with a long off period, while the small first flush in ‘Murano’ resulted in a more even crop distribution. Earliness of ripening and berry harvest was superior in ‘Favori’, which had a larger share of its crop during the first half-season. We conclude that it is possible by choosing the right rooting date and raising environment to produce plants with the same high quality and yield potential under the cool Nordic conditions as those currently produced in Central Europe.
Lemongrass Growth, Essential Oil, and Active Substances as Affected by Water Deficit
Authors: Mahmoud Nourhan , Abdou Mahmoud A. H. , Salaheldin Sabri , Soliman Wagdi Saber
Published: March 2022

Environmental stress has a major influence on the growth and quality of medicinal plants. More than half of the agricultural land worldwide suffers from a lack of water. In this study, we estimated the effect of different irrigation intervals on growth, yield, and essential oil content as well as their effect on the main compounds of the essential oil of lemongrass, Cymbopogon citratus. The major objective was to test how much irrigation consumption can be lowered without a significant impact on yield and quality properties. Water deficit led to significant decreases in growth characteristics including the number of tillers as well as fresh and dry herb yield. In addition, the relative leaf greenness decreased under water deficit, especially in plants irrigated every 20 days. In contrast, proline content increased with increasing water deficit, especially in plants irrigated every 15 and 20 days. Essential oil percentage also increased under a water deficit condition, and the highest essential oil percentage was observed in plants irrigated every 15 and 20 days. However, the yield of essential oil per plant significantly decreased due to decreasing the herb yield. GC-MS analysis identified 31 compounds, mainly geranial and neral. Geranial and neral percentage decreased under a water deficit of 10-day irrigation intervals but increased with increasing the water deficit severity at irrigation intervals of 15 and 20 days. These results suggest that the lemongrass plant was sensitive to drought. Nevertheless, the quality represented by essential oil percentage and the main active substances improved with prolonging the irrigation intervals. This study recommends increasing irrigation intervals to 10 days to maintain small decreases in the yield with higher quality. In addition, it is recommended to conduct more studies to improve the growth of lemongrass under water shortage conditions.
Landscape of Molecular Crosstalk Perturbation between Lung Cancer and COVID-19
Authors: Kuchi Aditi , Wu Jiande , Fuloria Jyotsna , Hicks Chindo
Published: March 2022

Background: Lung cancer patients have the worst outcomes when affected by coronavirus disease 2019 (COVID-19). The molecular mechanisms underlying the association between lung cancer and COVID-19 remain unknown. The objective of this investigation was to determine whether there is crosstalk in molecular perturbation between COVID-19 and lung cancer, and to identify a molecular signature, molecular networks and signaling pathways shared by the two diseases. Methods: We analyzed publicly available gene expression data from 52 severely affected COVID-19 human lung samples, 594 lung tumor samples and 54 normal disease-free lung samples. We performed network and pathways analysis to identify molecular networks and signaling pathways shared by the two diseases. Results: The investigation revealed a signature of genes associated with both diseases and signatures of genes uniquely associated with each disease, confirming crosstalk in molecular perturbation between COVID-19 and lung cancer. In addition, the analysis revealed molecular networks and signaling pathways associated with both diseases. Conclusions: The investigation revealed crosstalk in molecular perturbation between COVID-19 and lung cancer, and molecular networks and signaling pathways associated with the two diseases. Further research on a population impacted by both diseases is recommended to elucidate molecular drivers of the association between the two diseases.
Measurement Invariance and Construct Validity of the Satisfaction With Life Scale (SWLS) in Community Volunteers in Vietnam
Authors: Arrindell Willem A. , Checa Irene , Espejo Begoña , Chen I-Hua , Carrozzino Danilo , Vu-Bich Phuong , Dambach Huong , Vagos Paula
Published: March 2022

Worldwide, the Satisfaction With Life Scale (SWLS) has become the most widely used measure of life satisfaction. Recently, an authorized Vietnamese-language version has been introduced. Using a convenience sample comprising community volunteers from Ho Chi Minh City (N = 1073), confirmatory support was found for the cross-national constancy of the one-dimensional structure underlying the SWLS. Corrected item–total polyserial correlations and Omega coefficient were satisfactory. Using multi-group confirmatory factor analysis, configural, metric, and scalar invariance of the SWLS factorial structure were tested by gender, age, marital status, income, and educational level. Strong evidence of scalar invariance was found for gender and education, on which relevant subgroups did not differ in terms of latent means. Partial scalar invariance was found for marital status (item 4 and 5) and income (item 4). Being involved in an intimate relationship or having a higher income were associated with higher latent means. Scalar invariance in relation to age was very poor. Accordingly, caution must be exerted when comparing age groups. A high SWLS score was predictive of good self-rated health. Implications of the findings are briefly discussed.
Relationship between Multimorbidity and Disability in Elderly Patients with Coexisting Frailty Syndrome
Authors: Jędrzejczyk Maria , Foryś Weronika , Czapla Michał , Uchmanowicz Izabella
Published: March 2022

Background: Multimorbidity is a common problem worldwide. It carries the risk of reduced quality of life, disability, frequent hospitalizations, and death. The present study was designed to assess the relationships that exist between multimorbidity and disability in elderly patients. Methods: The study included 100 patients and was conducted between October 2020 and January 2021. Inclusion criteria included age >65 years, presence of a minimum of two comorbidities in the subject, and consent to participate in the study. Standardized survey instruments such as Tilburg Frailty Indicator (TFI), Charlson Comorbidities Index (CCI), Assessment of Basic Activities of Daily Living—Katz Scale (ADL), and Assessment of Complex Activities of Daily Living—Lawton Scale (IADL) were used in the study. Results: The majority of the subjects (92) had a frailty syndrome (TFI). A small group of respondents (8%) suffered from severe comorbidities (CCI). Among the subjects surveyed, 71% maintained full function in performing simple activities of daily living (ADL), while 29% demonstrated moderate disability on the scale. Full independence in performing complex activities of daily living (IADL) was present in 33% of the respondents, and 67% were partially independent. Independence in complex activities of daily living (IADL) was significantly higher in patients with fewer comorbidities. The severity of comorbidities (CCI) had a significant effect on the decrease in the level of independence (ADL and IADL). Independence in performing complex activities (IADL) was worse among older patients. Conclusions: An increase in the number of comorbidities contributes to a decrease in the level of performance of complex activities of daily living. The severity of comorbidities significantly reduces the level of independence of the subjects in simple and complex activities of daily living. In patients with a higher level of independence in performing simple and complex activities, the co-occurrence of frailty syndrome was less severe. As the age of the subjects increases, the frequency in which they show moderate dependence on third parties in performing complex activities of daily living increases.
Effects of Calcium on Arsenate Adsorption and Arsenate/Iron Bioreduction of Ferrihydrite in Stimulated Groundwater
Authors: Chen Mengna , Xie Zuoming , Yang Yang , Gao Ban , Wang Jia
Published: March 2022

The reduction and transformation of arsenic-bearing ferrihydrite by arsenate-iron reducing bacteria is one of the main sources of arsenic enrichment in groundwater. During this process the coexistence cations may have a considerable effect. However, the ionic radius of calcium is larger than that of iron and shows a low affinity for ferrihydrite, and the effect of coexisting calcium on the migration and release of arsenic in arsenic-bearing ferrihydrite remains unclear. This study mainly explored the influence of adsorbed Ca2+ on strain JH012-1-mediated migration and release of arsenate in a simulated groundwater environment, in which 3 mM ferrihydrite and pH 7.5. Ca2+ were pre-absorbed on As(V)-containing ferrihydrite with a As:Fe ratio of 0.2. Solid samples were analyzed by X-ray diffraction (XRD), scanning electron microscopic (SEM), Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS). The results show that calcium and arsenate can synergistically adsorb on ferrihydrite due to the electrostatic interactions, and the adsorbed Ca2+ mainly exists on the surface through the outer-sphere complex. Adsorbed Ca2+ entering the stimulated groundwater was easily disturbed and led to an extra release of 3.5 mg/L arsenic in the early stage. Moreover, adsorbed Ca2+ inhibited biogenic ferrous ions from accumulating on ferrihydrite. As a result, only 12.30% Fe(II) existed in the solid phase, whereas 29.35% existed without Ca2+ adsorption. Thus, the generation of parasymplesite was inhibited, which is not conducive to the immobilization of arsenic in groundwater.
Exploring Families’ Acceptance of Wearable Activity Trackers: A Mixed-Methods Study
Authors: Creaser Amy V. , Hall Jennifer , Costa Silvia , Bingham Daniel D. , Clemes Stacy A.
Published: March 2022

Background: The family environment plays a crucial role in child physical activity (PA). Wearable activity trackers (wearables) show potential for increasing children’s PA; however, few studies have explored families’ acceptance of wearables. This study investigated the acceptability of using wearables in a family setting, aligning experiences with components of the Technology Acceptance Model and Theoretical Domains Framework. Methods: Twenty-four families, with children aged 5–9 years, took part in a 5-week study, where all members were provided with a Fitbit Alta HR for 4 weeks. Acceptability was measured using weekly surveys and pre-post-questionnaires. Nineteen families participated in a focus group. Quantitative and qualitative data were integrated using the Pillar Integration Process technique. Results: Pillars reflected (1) external variables impacting wearable use and PA and (2) wearable use, (3) ease of use, (4) usefulness for increasing PA and other health outcomes, (5) attitudes, and (6) intention to use a wearable, including future intervention suggestions. Conclusions: Families found the Fitbit easy to use and acceptable, but use varied, and perceived impact on PA were mixed, with external variables contributing towards this. This study provides insights into how wearables may be integrated into family-based PA interventions and highlights barriers and facilitators of family wearable use.
Development of Critical Reflection Competency Scale for Clinical Nurses
Authors: Shin Sujin , Hong Eunmin , Do Jiyoung , Lee Mee Sun , Jung Youngsun , Lee Inyoung
Published: March 2022

Critical reflection develops nurses’ critical thinking and clinical reasoning competency. It is necessary to develop a validated scale to measure critical reflection competency considering the clinical situation and nursing context. Therefore, this study analyzed the concept of critical reflection, developed a scale to measure critical reflection competency, and verified its validity and reliability. The concept of critical reflection and components of the scale were confirmed through literature review and results of previous studies on content analysis. A total of 64 preliminary items were derived on a 5-point Likert scale. The adequacy of vocabulary and expression was checked, and a content validity test was conducted. An I-CVI value of 0.88–1.00 was computed. Construct validity was conducted through an exploratory factor analysis, and data collected from 296 clinical nurses were analyzed. Five factors and nineteen items were derived, and the explanatory power was found to be 53.02%. Cronbach’s α of the scale was 0.853. Future studies need to develop a critical reflection education program and utilize this concept as an educational strategy. We propose a study to verify the effect of applying an educational program using the critical reflection competency scale developed in this study.
Planned Physical Workload in Young Tennis Players Induces Changes in Iron Indicator Levels but Does Not Cause Overreaching
Authors: Żurek Piotr , Lipińska Patrycja , Antosiewicz Jędrzej , Durzynska Aleksandra , Zieliński Jacek , Kusy Krzysztof , Ziemann Ewa
Published: March 2022

The current study aimed to examine the impact of the training load of two different training camps on the immunological response in tennis players, including their iron metabolism. Highly ranked Polish tennis players, between the ages of 12 and 14 years, participated in two training camps that were aimed at physical conditioning and at improving technical skills. At baseline and after each camp, blood samples were analyzed, and the fatigue was assessed. The levels of pro- and anti-inflammatory indicators, iron, and hepcidin were determined. The levels of the heat shock proteins, (Hsp) 27 and 70, were also measured. All the effects were evaluated using magnitude-based inference. Although the training camps had different objectives, the physiological responses of the participants were similar. The applied programs induced a significant drop in the iron and hepcidin levels (a small-to-very-large effect) and enhanced the anti-inflammatory response. The tumor necrosis factor α levels were elevated at the beginning of each camp but were decreased towards the end, despite the training intensity being medium/high. The changes were more pronounced in the female players compared to the male players. Altogether, the results suggest that low-grade inflammation in young tennis athletes may be attenuated in response to adequately designed training. To this end, the applied physical workload with a controlled diet and rest-controlled serum iron levels could be the marker of well-designed training.
Implementing School-Based Mental Health Services: A Scoping Review of the Literature Summarizing the Factors That Affect Implementation
Authors: Richter Anne , Sjunnestrand My , Romare Strandh Maria , Hasson Henna
Published: March 2022

Background: Mental illness in children and youths has become an increasing problem. School-based mental health services (SBMHS) are an attempt to increase accessibility to mental health services. The effects of these services seem positive, with some mixed results. To date, little is known about the implementation process of SBMHS. Therefore, this scoping review synthesizes the literature on factors that affect the implementation of SBMHS. Methods: A scoping review based on four stages: (a) identifying relevant studies; (b) study selection; (c) charting the data; and (d) collating, summarizing, and reporting the results was performed. From the searches (4414 citations), 360 were include in the full-text screen and 38 in the review. Results: Implementation-related factors were found in all five domains of the Consolidated Framework for Implementation Research. However, certain subfactors were mentioned more often (e.g., the adaptability of the programs, communication, or engagement of key stakeholders). Conclusions: Even though SBMHS differed in their goals and way they were conducted, certain common implementation factors were highlighted more frequently. To minimize the challenges associated with these types of interventions, learning about the implementation of SBMHS and using this knowledge in practice when introducing SBMHS is essential to achieving the best possible effects with SMBHSs.
Burden of Cancer Due to Cigarette Smoking and Alcohol Consumption in Korea
Authors: Jung Yoon-Sun , Yoon Seok-Jun
Published: March 2022

This study aimed to estimate the burden of cancer in Koreans attributable to smoking and alcohol consumption using disability-adjusted life years and population attributable fractions. We estimated the burden of 12 cancers due to simultaneous and independent smoking and alcohol exposure in Koreans aged ≥40 years. In men, the cancer burden attributable to the combined risk factors, smoking alone, and alcohol consumption alone were 9.5, 14.8, and 6.1%, respectively; the corresponding values for women were 1.1, 2.5, and 2.7%, respectively. In men, tracheal, bronchial, and lung cancers were the most common cancer types. The disease burden may have been reduced by 16.8, 32.3, and 4.1% in the absence of the combined risk factors, smoking alone, and alcohol consumption alone, respectively. Our findings suggest that risk factor-based intervention may have the greatest preventative effect for lung cancer among all cancers in men. Our real-world data methodology could provide further evidence-based methods to explore and facilitate effective health promotion interventions for specific target groups and may lay the foundation for the establishment of healthcare services according to population subgroups or regional characteristics.
Structural Analysis of the Black-Legged Tick Saliva Protein Salp15
Authors: Chaves-Arquero Belén , Persson Cecilia , Merino Nekane , Tomás-Cortazar Julen , Rojas Adriana L. , Anguita Juan , Blanco Francisco J.
Published: March 2022

Salp15 is one of the proteins in the saliva of the tick Ixodes scapularis. Together with other biomolecules injected into the mammalian host at the biting site, it helps the tick to sustain its blood meal for days. Salp15 interferes with the cellular immune response of the mammalian host by inhibiting the activation of CD4+ T-lymphocytes. This function is co-opted by pathogens that use the tick as a vector and invade the host when the tick bites, such as Borrelia burgdorferi, the causative agent of Lyme borreliosis. Because of the immunity-suppressing role of Salp15, it has been proposed as a candidate for therapeutic applications in disorders of the immune system. The protein is produced as a 135-residue long polypeptide and secreted without its N-terminal signal 1–21 sequence. Detailed structural studies on Salp15 are lacking because of the difficulty in producing large amounts of the folded protein. We report the production of Salp15 and its structural analysis by NMR. The protein is monomeric and contains a flexible N-terminal region followed by a folded domain with mixed α + β secondary structures. Our results are consistent with a three-dimensional structural model derived from AlphaFold, which predicts the formation of three disulfide bridges and a free C-terminal cysteine.
A Comparative Analysis of Weizmannia coagulans Genomes Unravels the Genetic Potential for Biotechnological Applications
Authors: Aulitto Martina , Martinez-Alvarez Laura , Fiorentino Gabriella , Limauro Danila , Peng Xu , Contursi Patrizia
Published: March 2022

The production of biochemicals requires the use of microbial strains with efficient substrate conversion and excellent environmental robustness, such as Weizmannia coagulans species. So far, the genomes of 47 strains have been sequenced. Herein, we report a comparative genomic analysis of nine strains on the full repertoire of Carbohydrate-Active enZymes (CAZymes), secretion systems, and resistance mechanisms to environmental challenges. Moreover, Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) immune system along with CRISPR-associated (Cas) genes, was also analyzed. Overall, this study expands our understanding of the strain’s genomic diversity of W. coagulans to fully exploit its potential in biotechnological applications.