bluuebunny/crossref_metadata_2025 huggingface dataset:
СПІВВІДНОШЕННЯ КАТЕГОРІЇ «СВОБОДА ОСОБИ» ТА ДОТРИМАННЯ ТАЄМНИЦІ ДОСУДОВОГО РОЗСЛІДУВАННЯ ПІД ЧАС ЗАТРИМАННЯ ОСОБИ У КРИМІНАЛЬНОМУ ПРОВАДЖЕННІ
Authors: Почтовий М. М.
Published: April 2023

Дана наукова стаття присвячена актуальним питанням реалізації меж прав і свобод особи у кримінальному провадженні України, зокрема під час застосування такого заходу забезпечення кримінального провадження як затримання в порядку статті 208 Кримінального процесуального кодексу України. Спочатку наголошується про питання свободи в контексті суспільного життя, кримінально-процесуальній діяльності тощо. Зазначається, що свобода, окремі її прояви обмежуються юридичними нормами у вигляді правових заборон, адже бажання та інтереси людини не завжди збігають із інтересами суспільства, що змушує під впливом існуючих законів чинити так, щоб не порушувати інтересів суспільства. Підтвердженням авторської думки є принцип правового регулювання: «дозволено все, що не заборонено законом». Доведено, що свобода як явище дуже тісно пов’язана із правом, яке покликане своєю силою врегульовувати найбільш значущі сфери суспільного життя. Крім цього визначено, що право цивілізує, унормовує явища і процеси, визначає права і обов’язки суб’єктів, причетних до їх реалізації тощо. З’ясовано, що у статті 208 Кримінального процесуального кодексу України визначені обов’язкові відомості, що зазначаються у протоколі затримання, який вручається підозрюваному, зокрема: підстави затримання, результати особистого обшуку, тобто, підозрюваний з цього моменту стає обізнаним про наявні докази, на підставі яких його затримали. Крім цього, обов’язково викликається захисник з центру безоплатної вторинної правової допомоги, який також знайомиться з цими ж матеріалами. Встановлено, що одержана інформація про свідків та очевидців, докази, на підставі яких здійснено затримання, і яка за своєю сутністю є таємницею досудового розслідування, з цього моменту набуває властивості «доступної» і може бути використана для здійснення впливу на хід досудового розслідування. Насамкінець, сформульовано групу ризиків розповсюдження інформації, що становить таємницю досудового розслідування, під час затримання особи в порядку статті 208 Кримінального процесуального кодексу України.
ГАРАНТІЇ ЗАБЕЗПЕЧЕННЯ НАЦІОНАЛЬНОЇ БЕЗПЕКИ УКРАЇНИ В УМОВАХ ЄВРОІНТЕГРАЦІЇ: АСПЕКТ ІДЕНТИФІКАЦІЇ СУТНОСТІ
Authors: Наконечна І. В.
Published: April 2023

Стаття присвячена розкриттю сутності гарантій забезпечення національної безпеки України в умовах євроінтеграції. Уточнено, що гарантії як успіху реалізації цього процесу, так і можливості його завершення загалом є окремим та самостійним елементом у межах нормативно-правових засад реалізації адміністративно-правового механізму забезпечення національної безпеки України в умовах євроінтеграції. Вони можуть бути як чітко визначеними у системі законодавчих актів цієї сфери, так і опосередковано випливати з їхніх положень. Визначено, що нормативно-правові засади реалізації адміністративно-правового механізму забезпечення національної безпеки України в умовах євроінтеграції беруть свій початок з моменту проголошення незалежності України. На той час вже було усвідомлення необхідності забезпечення колективної безпеки шляхом партнерства та співробітництва у тому числі задля зміцнення миру та стабільності Європейського континенту. Їхнє оновлення зумовлено декількома чинниками, серед яких зокрема: глобалізаційні трансформації; зміни світового порядку в аспекті накопичення сил та впливів з боку окремих держав, що мало наслідком послаблення наявних безпекових систем; закінчення терміну дії підписаних угод; невиконання окремих положень договірних зобов’язань; внутрішні соціально-політичні процеси та кризи тощо. Гарантії, як елемент нормативно-правових засад реалізації адміністративно-правового механізму забезпечення національної безпеки України в умовах євроінтеграції, розподілено на дві групи. Йдеться про загальні гарантії реалізації цього процесу та конкретні гарантії, що є безпосередньо безпековими. Доведено, що загальні гарантії забезпечення національної безпеки України в умовах євроінтеграції є розпливчастими та такими, що потребують уточнення. Своєю чергою, конкретні гарантії забезпечення національної безпеки України в умовах євроінтеграції (гарантії безпеки) фактично є відсутніми. Наголошено, що на міжнародній арені має бути врегульовано питання щодо розбудови механізму довгострокового стратегічного співробітництва та партнерства між Україною, ЄС та іншими ключовими країнами (більшою мірою Великобританією та США) задля забезпечення її можливості самостійного захисту національних інтересів.
ТЕОРЕТИЧНИЙ АСПЕКТ ВЗАЄМОДІЇ СТАРОСТИ ТА ОКРЕМИХ ЕЛЕМЕНТІВ ГРОМАДЯНСЬКОГО СУСПІЛЬСТВА
Authors: Петрушевська В. К.
Published: April 2023

У статті висвітлено окремі аспекти взаємодії старости та окремих елементів громадянського суспільства. У статті зазначається, що з метою оперативного реагування на соціальні та інші проблеми мешканців, задоволення їх потреб староста здійснює взаємодію не тільки з органами державної влади та місцевого самоврядування, але й інститутами громадянського суспільства. Звертається увага на те, що ефективне вирішення питань розвитку територіальної громади можливо лише за наявності налагодженої взаємодії, активного діалогу між старостою та інститутами громадянського суспільства. Останні в свою чергу відіграють важливого значення в економічній, освітній, культурній, соціальній сферах розвитку та функціонування територіальної громади. Далі вказується, що сьогодні залишаються недостатньо осмисленими питання теоретичного аспекту взаємодії старости з окремими елементами громадянського суспільства, не достатньо висвітлені та досліджені оптимальні форми та елементи такої взаємодії, особливості її здійснення. Робиться висновок, що роль взаємодії старости з інститутами громадянського суспільства в процесах побудови демократичного суспільства і децентралізації влади зростає і вимагає відкритості, гласності діяльності, довіри та безперервності процесу залучення громадян, громадських об’єднань, волонтерів тощо до співпраці з метою вироблення необхідних громадянам рішень, вирішення нагальних питань розвитку територіальної громади. Обґрунтовується, що створення ефективної взаємодії старости із інститутами громадянського суспільства передбачає інформування та постійний спільний аналіз проблем з питань розвитку територіальної громади, налагодження різних форм двостороннього зв’язку, забезпечення довіри з боку мешканців територіальної громади до місцевої влади. Вказується, що подальших наукових досліджень потребують проблематичні питання взаємодії старости з інститутами громадянського суспільства в контексті реформ та трансформаційних процесів.
Using Multispectral Images to Establish Land Categories
Authors:   Department of Land Management, Petro Mohyla Black Sea National University, Mykolaiv, Ukraine.  Email: levperovych@gmail.com, Perovych Lev , Perovych Ihor ,   Department of Economic Expertise & Land Management, West Ukrainian National University, Ternopil, Ukraine.  Email: cadastr@gmail.com, Lazarieva Olena ,   Department of Land Management, Petro Mohyla Black Sea National University, Mykolaiv, Ukraine.  Email: lazareva95@ukr.net, Mas Andrei ,   Department of Land Management, Petro Mohyla Black Sea National University, Mykolaiv, Ukraine.  Email: andreimas 1959@gmail.com
Published: April 2023

At the present stage, the dominant means of obtaining information is space shooting, which is carried out from space carriers with the help of special shooting equipment, and makes it possible to obtain high-quality images covering a significant area of the earth's surface. Methods combining multi-criteria analysis and GIS technologies can be used to make appropriate environmental decisions. At the same time, an important component for all interested parties is obtaining the original information at the lowest cost. In this regard, this publication provides a methodology for constructing maps of land categories, which is based exclusively on a free basis. This methodology includes free and open FOSS software, space images of the Landsat 8 satellite, and multi-criteria analysis of space image processing. The procedure of the methodology includes the creation of a database based on available land management documents, cadastral plans and maps, satellite images, etc.; processing of the database using multi-criteria analysis; analysis of the results and decision-making. The database is created using QGIS software, and PostgreSQL with the PostGIS extension is used for modeling and data storage. MultiSpec software was used to create multispectral images, perform satellite image classification and evaluation. Using a set of the above software products and Landsat 8 satellite images, a pilot project on an area of 615 km2 was carried out to determine the capabilities of this methodology for establishing land categories. It was established that the multispectral image of the combination of 6-5-2 channels best represents land categories. The accuracy of the classification is 96.2%, and the User Accuracy for arable land is almost 100%, for orchards 55%, and for hayfields and pastures 61.3%.
In-betweenness and Migration Interdependence: Lessons from Georgia, Moldova, and Ukraine
Authors:   University of Macedonia, Blouchoutzi Anastasia , Pedi Revecca
Published: April 2023

In this paper, we draw on the concepts of in-betweenness and migration interdependence in order to investigate the vulnerability of Georgia, Moldova, and Ukraine due to their confl icting relations with Russia and the exposure of their economies to remittance flows from the latter. To achieve this goal, we explore whether and how migrant flows and remittance flows have diverged since 2014, when the three states signed their Association Agreements with the EU and their economic relations with Russia deteriorated. In this respect, we examine how interstate relations impact upon migration and remittances flows. After discussing in-betweenness and migration interdependence, we investigate the origin of the remittance inflows in Georgia, Moldova, and Ukraine and the destination of the migration outfl ows. We map the development of remittances from the World, Europe, and Russia and relate it with the development of their GDP using longitudinal data. A comparative analysis of our findings suggest that the three cases differ from each other, but, in all three cases, Russia has not used migration interdependence as leverage. We conclude that remittance flows in the three in-between states are more affected by the state of the global economy, the economic situation of Russia, and domestic circumstances rather than from interstate relations.
DEMANDA DE IMPORTACIÓN DE CAMARÓN ECUATORIANO EN ESTADOS UNIDOS PARA EL PERIODO 1990-2018
Authors: León-Cando Christopher Javier , Tonon Ordonez Luis Bernardo
Published: April 2023

Gran parte del crecimiento que ha tenido la industria camaronera en el Ecuador se debe a que Estados Unidos históricamente ha sido el principal comprador/importador de camarón ecuatoriano. Es por ello, que esta investigación tuvo como objetivo estimar la demanda de importación de camarón ecuatoriano de Estados Unidos entre 1990 y 2018. Las variables utilizadas fueron los precios del camarón ecuatoriano y tailandés, la renta de los consumidores americanos explicada a través del PIB de Estados Unidos y la presencia del virus de la mancha blanca en el camarón ecuatoriano como variable dummy. El método de estimación utilizado fue Mínimos Cuadrados Generalizados. Los resultados del modelo mostraron que las variables utilizadas explicaron esta demanda y que el precio del camarón ecuatoriano y la renta de los consumidores americanos, fueron las variables más significativas que deberían analizar los empresarios camaroneros del Ecuador, para ingresar a este mercado o incrementar sus exportaciones.Palabras clave: Camarón ecuatoriano, Demanda, Estados Unidos, importaciones, Mínimos Cuadrados Generalizados

Abstract

Great part of the shrimp industry growth in Ecuador is due to the fact that the United States has historically been the main buyer/importer of Ecuadorian shrimp. For this reason, this research aimed to estimate the US import demand for Ecuadorian shrimp between 1990 and 2018. The variables used were the prices of Ecuadorian and Thai shrimp, the American consumers’ income explained through the GDP of the United States and the presence of the white spot virus in Ecuadorian shrimp as a dummy variable. The estimation method used was Generalized Least Squares. The results of the model showed that the variables used explained this demand and that the price of Ecuadorian shrimp and the American consumers’ income were the most significant variables that Ecuadorian shrimp businessmen could analyze to enter this market or increase their exports.Keywords: Ecuadorian shrimp, Demand, The United States, imports, Generalized Least Squares
Mucosite oral em crianças e adolescentes: uma revisão integrativa da literatura
Authors: Lima Cinthya Gabriella dos Santos , Silva Mayara Kevelin Lima da , Ramalho Maria Eduarda Guimarães de Andrade Teixeira , Dourado Regitânia Vieira , Rego Victória Gabriela Brasil , Souto Nyedja Myllena de Lima , Silva-Selva Elizabeth Louisy Marques Soares da
Published: April 2023

A mucosite oral (MO) é uma doença inflamatória aguda observada em pacientes oncológicos, provocada pelas terapias antineoplásicas. Sendo assim, o presente estudo teve como objetivo verificar, na literatura disponível, os tipos de tratamento, prevenção e características gerais da MO. Foi realizada uma revisão integrativa da literatura através da busca nas bases de dados eletrônicas PubMed e Periódicos CAPES. A estratégia de busca foi baseada na pesquisa dos descritores “oral mucositis”, “child”, “adolescent”. Foram selecionados artigos publicados, no idioma inglês, entre os anos de 2017 e 2022. Assim, a busca online resultou em 49 estudos selecionados de acordo com os descritores utilizados, sendo 20 provenientes da base de dados PubMed e 29 do Periódico CAPES. Destes, 19 artigos atenderam à abordagem do tema, considerados estudos relevantes e incluídos nesta revisão de literatura. Entretanto, este trabalho contribuiu para identificar as diferentes formas de tratar a MO em pacientes submetidos à quimioterapia e/ou radioterapia, que ainda assim não apresenta um único protocolo.  O conhecimento sobre a causa da MO, bem como suas características gerais, é de fundamental importância para o desenvolvimento, prevenção e contribuição para a saúde de forma geral da criança submetida ao tratamento de câncer.
Incidência de acidentes ofídicos no estado de Sergipe: uma revisão de literatura associada a estudo ecológico
Authors: Nascimento Adriel Barbosa do , Lima Bianca de Araújo , Silva Júnior Adriano Bezerra da , Lemos André Luis Conceição , Santos Rafael Valença de Souza , Nascimento Lucas Cerqueira Gomes Barbosa do
Published: April 2023

Os acidentes ofídicos representam um grave problema para a saúde pública em todo o mundo por impactar diretamente nos gastos com tratamento e reabilitação dos pacientes vítimas de envenenamento por picada de cobra. Os casos mais frequentes ocorrem em países tropicais, como o Brasil, podendo ter seu número subestimado em locais com menos acesso a serviços de saúde. Diante da relevância do assunto, o objetivo do presente estudo é fornecer uma visão ampla acerca da epidemiologia dos acidentes ofídicos no estado de Sergipe, explorando fatores relevantes para a incidência de casos. Foi realizado um estudo do tipo revisão de literatura nas bases de dados indexadas às plataformas BVS, Pubmed, Scielo e UpToDate, onde foram selecionados 16 artigos de forma definitiva. Foi analisado que a incidência de casos de acidentes ofídicos em Sergipe mantém-se constante, com pouca variação entre os anos analisados. Entre os fatores de risco associados, destaca-se sexo masculino, faixa etária em idade produtiva e o atraso no atendimento médico. O uso de soroterapia nos casos necessários demonstra ser eficaz e modificador de desfecho clínico.
A method for performing tendon suture of superficial and deep finger flexor tendons
Authors:   O. V. Vladimirtsev Regional Clinical Hospital of the Ministry of Health of the Khabarovsk Krai, Sergeyev A.P. , Boyarshinov M.A. ,   O. V. Vladimirtsev Regional Clinical Hospital of the Ministry of Health of the Khabarovsk Krai
Published: April 2023

Injury to the flexor tendons of the fingers is a common injury, which, if not properly treated and rehabilitated, can cause dysfunction and severe deformities. The article presents a new method of performing a suture of the tendon of the finger and analyzes the results of applying this technique on 6 patients of the trauma department with damage to the superficial and deep extensor of the fingers
Employment contract with a medical worker under the new legislation
Authors:   Far Eastern State Medical University of the Ministry of Health of Russia, Savkov D.S. , Savkova V.M. ,   Postgraduate Institute for Public Health Workers under Health Ministry of Khabarovsk Krai
Published: April 2023

The article analyzes the legislative acts regulating the requirements for the content and procedure for concluding an employ- ment contract with a medical worker
Gout, hyperuricemia: status of the issue
Authors:   Clinical Diagnostic Center of the Ministry of Health of the Khabarovsk Krai, Pyatnitskaya P. I. , Otteva E.N. ,   Postgraduate Institute for Public Health Workers under Health Ministry of Khabarovsk Krai
Published: April 2023

Uric acid (UA) is very important for the human body. In addition to the positive aspects of UA, its elevated level is an independent risk factor for endothelial damage, and therefore the occurrence and progression of a number of chronic non-communicable diseases (CNCD), such as cardiovascular events, chronic kidney disease, metabolic syndrome, insulin resistance, type 2 diabetes mellitus, which has been proven in numerous clinical and epidemiological studies. The article presents data on the metabolism of uric acid and hyperuricemia, on its effect on the body, on the pathogenesis of diseases that can develop with long-term persistent hyperuricemia. A review of the clinical recommendations of the medical communities for prescribing urate-lowering therapy is presented
Twenty-year record of white pox disease in the Florida Keys: importance of environmental risk factors as drivers of coral health
Authors: Sutherland KP , Griffin A , Park A , Porter JW , Heron SF , Eakin CM , Berry B , Kemp DW , Kemp KM , Lipp EK , Wares JP
Published: April 2023

Declining coral populations worldwide place a special premium on identifying risks and drivers that precipitate these declines. Understanding the relationship between disease outbreaks and their drivers can help to anticipate when the risk of a disease pandemic is high. Populations of the iconic branching Caribbean elkhorn coral Acropora palmata have collapsed in recent decades, in part due to white pox disease (WPX). To assess the role that biotic and abiotic factors play in modulating coral disease, we present a predictive model for WPX in A. palmata using 20 yr of disease surveys from the Florida Keys plus environmental information collected simultaneously in situ and via satellite. We found that colony size was the most influential predictor for WPX occurrence, with larger colonies being at higher risk. Water quality parameters of dissolved oxygen saturation, total organic carbon, dissolved inorganic nitrogen, and salinity were implicated in WPX likelihood. Both low and high wind speeds were identified as important environmental drivers of WPX. While high temperature has been identified as an important cause of coral mortality in both bleaching and disease scenarios, our model indicates that the relative influence of HotSpot (positive summertime temperature anomaly) was low and actually inversely related to WPX risk. The predictive model developed here can contribute to enabling targeted strategic management actions and disease surveillance, enabling managers to treat the disease or mitigate disease drivers, thereby suppressing the disease and supporting the persistence of corals in an era of myriad threats.
Adipose tissue estimation of foraging and nesting green turtles Chelonia mydas using bioelectrical impedance analysis
Authors: Kophamel S , Ward LC , Mendez D , Ariel E , Bell I , Shum E , Munns SL
Published: April 2023

Adipose tissue is the main energy store in sea turtles and fluctuates in response to dietary conditions and external stressors. Monitoring programmes commonly use body condition indices (BCIs) to infer the nutritional and health status of sea turtle populations. However, BCIs have poor predictive power for estimating adipose tissue. We introduce the use of bioelectrical impedance analysis (BIA) as a portable technique to estimate adipose tissue in green turtles Chelonia mydas. The aims of this study were to estimate adipose tissue of green turtles on the Great Barrier Reef (Australia), and to examine whether adipose tissue is a more sensitive indicator than BCI. Turtles (n = 250) were sampled at 3 foraging sites and at a nesting beach with differing levels of anthropogenic impact. Differences in adipose tissue, Fulton’s BCI, and body mass across study sites and life stages were assessed by conducting linear mixed effects models. BIA estimates of mean adipose tissue revealed significant differences across life stages and sampling sites, that were not found using BCI data. Mean adipose tissue was estimated to be 4.6 ± 0.6% (% body mass ± SD) and was not correlated with mean BCI (1.2 ± 0.1). Adipose tissue was not reduced in turtles foraging at sites with a high level of anthropogenic impact. Adult turtles had significantly higher adipose tissue values than juveniles and subadults. Adult females measured during and shortly before nesting season had the highest adipose tissue values (%). BIA is a practical method for estimating adipose tissue, and we recommend this technique for consideration in sea turtle monitoring programmes.
Geography of News
Authors:   , Özgün Burcu
Published: April 2023

This dissertation provides insights into the systematic regional variations in news content and unveils their regional determinants as well as their influence on the behavior of economic agents. It features three chapters with empirical analyses of the German news media, each
addressing one of three distinct relations in the complex regional news system. The first chapter evaluates the potential of media data to capture regional peculiarities. The following chapter digs deeper into the alignment of regional news media coverage and innovation activities in regions. The third chapter shows how regional news content explains differences in people’s behavior. The dissertation establishes two news-related datasets at the sub-national level in Germany. In sum, the dissertation contributes to a better understanding of sub-national heterogeneity in media reporting, by showing that regional differences in media content both explain and are explained by regional socio-economic characteristics. The findings substantiate the potential of analyzing subnational developments through the use of news media information. Thereby this dissertation marks a starting point and reference for scholars aiming to study this promising area of research.
An international empirical study on the fiscal surplus from the perspective of sectoral balances
Authors: Garzón Espinosa Eduardo , Cruz Hidalgo Esteban , Medialdea García Bibiana , Sánchez Mato Carlos
Published: April 2023

The simultaneous recording of public surplus with current account deficit in a national economy could be related to strong private leverage that usually ends in financial crisis, what would make the public surplus unsustainable. The objective of this work is to check the extent to which this claim is bolstered by empirical support. The results reveal that, in effect, the concurrence of public surpluses and current account deficits is associated with private leverage processes and financial crises. These outcomes question the design of the current fiscal rules since they don’t pay attention to the current account balance.
Kesuksesan Implementasi SIMDA untuk Meningkatkan Akuntabilitas Pengelolaan Keuangan Pemerintah
Authors: Dwi Dayanti Oktavia  , Erwin Saraswati  , Zaki Baridwan
Published: April 2023

This research aimed to analyze the factors that influence regional management information system (SIMDA) using modified DeLone and McLean model approach in the government of Palangka Raya. This study applied a quantitative approach with the questionnaires as data collection techniques. Data analysis using Structural Equation Model (SEM) with 2.0 SmartPLS program. The sample used in this study were 84 respondents drawn from 28 SKPD Government of Palangkaraya. The results of this study indicate that construct quality systems affect the use and satisfaction of users, then the importance of the system affect the user satisfaction and user satisfaction effect on net benefits.
Abstrak
Penelitian ini bertujuan untuk menganalisis faktor-faktor yang mempengaruhi kesuksesan sistem informasi manajemen daerah dengan pendekatan model DeLone dan McLean yang dimodifikasi pada pemerintah Kota Palangka Raya. Penelitian ini menggunakan pendekatan kuantitatif dengan kuesioner sebagai teknik pengumpulan data. Analisis data menggunakan Structural Equation Model (SEM) dengan program SmartPLS 2.0. Sampel yang digunakan dalam penelitian ini adalah 84 responden yang diambil dari 28 SKPD Pemerintah Kota Palangka Raya. Hasil penelitian ini menunjukkan bahwa konstruk kualitas sistem berpengaruh terhadap penggunaan dan kepuasaan pengguna, selanjutnya pentingnya sistem berpengaruh terhadap kepuasaan pengguna dan kepuasaan pengguna berpengaruh terhadap manfaat bersih.
Income Smoothing: Apakah Ukuran Perusahaan Memoderasi?
Authors: Ratna Wijayanti Daniar Paramita  , Isarofah
Published: April 2023

This study aims to analyse whether the firm size become variable moderation to influence profitability, leverage and dividend policy toward income smoothing. This research has an underlying idea that income smoothing practices often undertaken with the aim of attracting investors, but it would need to be re-examined what factors affecting the practice of smoothing earnings and whether the size of the company will strengthen or weaken the income smoothing practices. The sample used are 26 manufacturing companies listed on the Stock Exchange in 2010-2014. The result showed that the size of the company became a moderating variable for leverage on income smoothing. On the contrary, for the profitability and dividend policy on income smoothing, company size not became moderating variable.
Abstrak
Penelitian ini bertujuan untuk menganalisa apakah ukuran perusahaan merupakan variabel moderasi untuk pengaruh profitabilitas, leverage dan kebijakan deviden terhadap income smoothing. Penelitian ini didasari oleh pemikiran bahwa praktik perataan laba seringkali dilakukan dengan tujuan menarik minat investor; namun perlu kiranya diteliti kembali faktor-faktor yang mempengaruhi praktik perataan laba dan apakah besar kecilnya perusahaan akan memperkuat atau memperlemah praktik perataan laba tersebut. Sampel penelitian ini adalah 26 perusahaan manufaktur yang terdaftar di BEI tahun 2010-2014. Hasil analisis menunjukkan bahwa ukuran perusahaan hanya menjadi variabel moderasi untuk pengaruh variabel leverage terhadap perataan laba. Sedangkan, untuk variabel profitabilitas dan kebijakan dividen terhadap perataan laba, ukuran perusahaan tidak menjadi variabel moderasi.
Determinan Kualitas Sistem Pengendalian Internal Pemerintah
Authors: Rusnindita Kartika , Rosidi  , Baridwan Zaki
Published: April 2023

This study aims to examine empirically the factors that affect quality of internal the government control system. This study uses a grand theory includes stewardship theory, agency theory, theory of planned behavior, and social cognitive theory. A research model is formed by using multiple constructs which consist of the leaders support, quality of internal audit, good governance, human resource competencies, and organizational culture. The primary data was collected based on Proportional Stratified Random Sampling to the 154 heads of SKPD, Head/Sector, and Head of Section as respondents. The data was analyzed based on Partial Least Square (PLS). This study shows that the leaders support, quality of internal audit, and organizational culture affect the quality of the government internal control system. This study was not able to prove that good governance and human resource competencies affect the quality of the government internal control system.
Abstrak
Penelitian ini bertujuan untuk menguji secara empiris faktor-faktor yang berpengaruh terhadap kualitas Sistem Pengendalian Internal Pemerintah. Teori yang digunakan adalah teori pelayanan, teori keagenan, teori perilaku terencana, dan teori kognitif sosial. Model penelitian ini dibentuk dengan menggunakan beberapa konstruk di antaranya dukungan pemimpin, kualitas audit intern, good governance, kompetensi sumber daya manusia, dan budaya organisasi. Teknik pengambilan sampel adalah Proportional Stratified Random Sampling terhadap 154 Kepala SKPD, Kepala Bagian/Bidang (Kabag/Kabid), dan Kepala Seksi (Kasi) sebagai responden. Teknik analisis data menggunakan Partial Least Square (PLS). Penelitian ini berhasil membuktikan bahwa dukungan pemimpin, kualitas audit intern, dan budaya organisasi berpengaruh terhadap kualitas sistem pengendalian internal pemerintah. Akan tetapi, penelitian ini tidak berhasil membuktikan bahwa good governance dan kompetensi sumber daya manusia berpengaruh terhadap kualitas sistem pengendalian internal pemerintah.
To the comparative evaluation of three-link buses of different compound schemes for traffic stability
Authors:   National Transport University, Poljakov Viktor , Popelych Denys ,   SE “State Road Transport Research Institute”, Sakhno Volodymyr ,   National Transport University, Filipova Galyna ,   National Transport University, Sharai Svitlana ,   National Transport University
Published: April 2023

The article develops a mathematical model describing the movement of a three-link articulated bus (two-axle bus and two single-axle trailers), further ТAВ, as a four-mass system, taking into account the control wheel module of the bus. The system allows to study the influence of the design parameters of the bus and trailers on the stability of the ТAВ. The object of the study is the stability of the articulated bus with drive either on the axle of the bus or on the axle of the first trailer. The purpose of the work is a comparative evaluation of articulated buses with drive either on the bus axle or on the axle of the trailer in terms of stability. Research methods – mathematical modeling of the stability of the movement of a three-link articulated bus (two-axle bus and two uniaxial trailers) with drive either on the bus axle or on the axle of the first trailer. As a result of the study, it was found that at the selected values of the design parameters of the ТAВ, the critical speed when applying traction to the bus axis was 31.19 m / s, which exceeds the maximum speed of its movement. When implementing traction on the axis of the trailer, the loss of stability of circular stationary modes is realized at values of 0.08 <alpha <0.09 (alpha – coefficient determining the share of normal reaction of the bearing surface on the wheels of the bus or trailer driving wheels), and the loss of stability of rectilinear motion – at alpha = 0,0815. The critical velocity in this case is vkp = 12.34 m / s. Analysis of the conditions of static stability of the ТAВ during the implementation of traction on the axis of the trailer showed that the value of the drag coefficient does not affect the critical speed (not included in the expression of critical speed), and the value of rolling resistance coefficients on the first and second axles slightly affects the critical speed . and a critical value of the alpha parameter that determines the amount of traction. At the same time, even with optimally selected stiffness and layout parameters, the critical speed of articulated buses does not exceed 12.5 m / s, that is, such buses need a special system of opposition. Keywords: articulated bus, stability, critical speed, traction force, driving mode, trailer, support surface reaction.
Current state of motor transport and direction of development of technical operation of vehicles
Authors:   Kharkiv National Automobile and Highway University, Volkov Vladimir , Volkova Tetiana ,   Kharkiv National Automobile and Highway University, Gorbik Yurii ,   Kharkiv National Automobile and Highway University
Published: April 2023

The state and main systemic problems of road transport in Ukraine at the present stage are considered. Peculiarities of application of strategies and tactics of modern system of technical operation of cars on public motor transport are shown. The basic principles of the adaptive system of maintenance and repair of rolling stock of motor transport are stated. On the example of the existing systems on transport new technologies of creation of information systems of organizational and functional support of processes of technical operation of cars at stages of a life cycle are offered. The results of experimental researches which are received by means of the information software complexes developed by authors are resulted. Keywords: motor transport, car maintenance, maintenance and repair, adaptive system, individual maintenance, information systems.
The problem of optimizing laboratory compaction of asphalt concrete mixtures
Authors:   Kharkiv National Automobile & Highway University, Zolotaryov Viktor , Ilin Yaroslav ,   Kharkiv National Automobile & Highway University, Kipnis Denys ,   SE “Dorcentr”, Ekimov Vitalii ,   Technologist of Avtomagistral-Pivden LLC
Published: April 2023

The problem of ensuring the durability and operation of asphalt concrete layers of non-rigid road surfaces is closely related to the quality of the materials used, their composition and installation technology. The latter includes two defining stages: moving mixtures and their compaction. At the same time, the prediction of the properties of asphalt concrete should be carried out based on the results of laboratory tests, in the process of which the road, climatic and transport conditions of operation of one or another layer are taken into account. Reliable prediction can be ensured if the conditions of laboratory research and production processes are identical. This mostly applies to the laboratory seal, which must match the production seal. The existing state of affairs does not meet this condition. For many decades, laboratory compaction was carried out by pressing asphalt concrete mixtures under a pressure of 20 MPa with vibration up to 40 MPa. Western European researchers and builders have been aware of this problem for more than 50 years. Due to this, fundamentally new methods of laboratory compaction appeared in the world (impact and vibration-impact type, rolling with metal and pneumatic rollers, displacement with pressure in the case of rotary presses). In Ukrainian practice, such methods are practically not used, despite the fact that the first rolling press was developed in KADI. The results of comparative studies of asphalt concrete compacted by the following methods: pressing, sector rolling, and rotary compaction are presented. Attention to the advantages and disadvantages of each of them is accepted. Keywords: asphalt concrete mixture, compaction by pressing, rolling, rotary shear, kinetics of gradual compaction, bitumen content.
Experience of using the domestic stabilizing additive ARON-BV for stone-mastic asphalt mixes
Authors:   National Transport University, Nevinhlovskyi Vadym , Stozhka Vitalii ,   National Transport University, Shnaider Mykhailo ,   LLC «Trade House Aron»
Published: April 2023

The article covers the issue of development, approval, implementation and further use of a domestic stabilizing additive for the production of stone-mastic asphalt mixes. The prerequisite for the creation of such a project was the development of the latest technologies and road construction materials, both on the world and Ukrainian industry markets, as well as the annual growth in the need for such materials during the implementation of infrastructure projects. Based on the results of the work, it was established that the quality of the domestically produced stabilizing additive corresponds to the level of quality of similar imported goods, and its cost is somewhat lower compared to foreign analogues. The total period of implementation of this project is eight years, taking into account the time for: development and approval of the necessary technical and permit documents; launch of a production technological line; approval and introduction of a stabilizing additive; observation for 6-7 years of implemented objects in the first year of implementation of the material; implementation of new facilities using the developed stabilizing additive. The results of this work can be used during the implementation of future infrastructure projects for the restoration and development of public highways, both in terms of ensuring the availability of domestic materials on the domestic market, and in terms of supporting and developing the domestic economy of Ukraine at the appropriate level. Keywords: wastepaper, stabilizing additive, technical and economic indicator, cellulose fiber, stone-mastic asphalt mixes, stone-mastic asphalt.
Sense of smell in chronic rhinosinusitis: A multicentric study on 811 patients
Authors: Macchi Alberto , Giorli Alessia , Cantone Elena , Carlotta Pipolo Giorgia , Arnone Flavio , Barbone Umberto , Bertazzoni Giacomo , Bianchini Chiara , Ciofalo Andrea , Cipolla Federica , De Massimi Alessio , De Vita Carla , Di Lieto Cristina , Ghidini Angelo , Govoni Marco , Gramellini Giulia , Maselli Del Giudice Alessandro , Ottaviano Giancarlo , Seccia Veronica , Sireci Federico , Sollini Giacomo , Staffieri Claudia , Gallo Stefania , Heffler Enrico , Mantia Ignazio La , De Corso Eugenio , Canevari Frank Rikki , Lombardo Nicola , Malvezzi Luca , Orietti Gabriele , Pasquini Ernesto , Presutti Livio , Monti Giulia
Published: April 2023

Introduction

The impairment of the sense of smell is often related to chronic rhinosinusitis (CRS) with or without nasal polyps (CRSwNP, CRSsNP). CRSwNP is a frequent condition that drastically worsens the quality of life of those affected; it has a higher prevalence than CRSsNP. CRSwNP patients experience severe loss of smell with earlier presentation and are more likely to experience recurrence of their symptoms, often requiring revision surgery.

Methods

The present study performed a multicentric data collection, enrolling 811 patients with CRS divided according to the inflammatory endotype (Type 2 and non-Type 2). All patients were referred for nasal endoscopy for the assessment of nasal polyposis using nasal polyp score (NPS); Sniffin’ Sticks olfactory test were performed to measure olfactory function, and SNOT-22 (22-item sinonasal outcome test) questionnaire was used to assess patients’ quality of life; allergic status was evaluated with skin prick test and nasal cytology completed the evaluation when available.

Results

Data showed that Type 2 inflammation is more common than non-type 2 (656 patients versus 155) and patients suffer from worse quality of life and nasal polyp score. Moreover, 86.1% of patients with Type 2 CRSwNP were affected by a dysfunction of the sense of smell while it involved a lesser percentage of non-Type 2 patients. Indeed, these data give us new information about type-2 inflammation patients’ characteristics.

Discussion

The present study confirms that olfactory function weights on patients’ QoL and it represents an important therapeutic goal that can also improve patients’ compliance when achieved. In a future – and present – perspective of rhinological precision medicine, an impairment of the sense of smell could help the clinician to characterize patients better and to choose the best treatment available.
Functional insights to the development of bioactive material for combating bacterial infections
Authors: Fan Duoyang , Liu Xiaohui , Ren Yueming , Bai Shuaige , Li Yanbing , Luo Ziheng , Dong Jie , Chen Fei , Zeng Wenbin
Published: April 2023

The emergence of antibiotic-resistant “superbugs” poses a serious threat to human health. Nanomaterials and cationic polymers have shown unprecedented advantages as effective antimicrobial therapies due to their flexibility and ability to interact with biological macromolecules. They can incorporate a variety of antimicrobial substances, achieving multifunctional effects without easily developing drug resistance. Herein, this article discusses recent advances in cationic polymers and nano-antibacterial materials, including material options, fabrication techniques, structural characteristics, and activity performance, with a focus on their fundamental active elements.
Antibiotic susceptibility pattern of Portuguese environmental Legionella isolates
Authors: Cruz Carolina , Rodrigues Lúcia , Fernandes Filipa , Santos Ricardo , Paixão Paulo , Chasqueira Maria Jesus
Published: April 2023

Introduction

Legionnaires’ Disease is a pneumonia caused by Legionella spp., currently treated empirically with fluoroquinolones and macrolides. In this study, we aim to describe the antibiotic susceptibility pattern of environmental Legionella recovered in the south of Portugal.

Methods

Minimal inhibitory concentration (MIC) determination of 57 Legionella isolates (10 Lp sg 1, 32, Lp sg 2-14 15 L. spp) was achieved by broth microdilution, as described by EUCAST, for azithromycin, clarithromycin, ciprofloxacin, levofloxacin, and doxycycline.

Results

Fluoroquinolones were the most active antibiotic, displaying the lowest MIC values in contrast to doxycycline which had the highest. MIC90 and epidemiological cut-off (ECOFF) values were, respectively, 0.5/1 mg/L for azithromycin, 0.125/0.25 mg/L for clarithromycin, 0.064/0.125 mg/L for ciprofloxacin, 0.125/0.125 mg/L for levofloxacin and 16/32 mg/L for doxycycline.

Discussion

MIC distributions were higher than reported by EUCAST for all antibiotics. Interestingly, two phenotypically resistant isolates with high-level quinolone resistance were identified. This is the first time that MIC distributions, lpeAB and tet56 genes have been investigated in Portuguese environmental isolates of Legionella.
The sex-dependent response to psychosocial stress and ischaemic heart disease
Authors: Helman Tessa J. , Headrick John P. , Stapelberg Nicolas J. C. , Braidy Nady
Published: April 2023

Stress is an important risk factor for modern chronic diseases, with distinct influences in males and females. The sex specificity of the mammalian stress response contributes to the sex-dependent development and impacts of coronary artery disease (CAD). Compared to men, women appear to have greater susceptibility to chronic forms of psychosocial stress, extending beyond an increased incidence of mood disorders to include a 2- to 4-fold higher risk of stress-dependent myocardial infarction in women, and up to 10-fold higher risk of Takotsubo syndrome—a stress-dependent coronary-myocardial disorder most prevalent in post-menopausal women. Sex differences arise at all levels of the stress response: from initial perception of stress to behavioural, cognitive, and affective responses and longer-term disease outcomes. These fundamental differences involve interactions between chromosomal and gonadal determinants, (mal)adaptive epigenetic modulation across the lifespan (particularly in early life), and the extrinsic influences of socio-cultural, economic, and environmental factors. Pre-clinical investigations of biological mechanisms support distinct early life programming and a heightened corticolimbic-noradrenaline-neuroinflammatory reactivity in females vs. males, among implicated determinants of the chronic stress response. Unravelling the intrinsic molecular, cellular and systems biological basis of these differences, and their interactions with external lifestyle/socio-cultural determinants, can guide preventative and therapeutic strategies to better target coronary heart disease in a tailored sex-specific manner.
Amlodipine rescues advanced iron overload cardiomyopathy in hemojuvelin knockout murine model: Clinical implications
Authors: Zhabyeyev Pavel , Sadasivan Chandu , Shah Saumya , Wang Faqi , Oudit Gavin Y.
Published: April 2023

Background

Iron overload cardiomyopathy (IOC) is a major co-morbidity of genetic hemochromatosis and secondary iron overload with limited therapeutic options. We aim to investigate mechanisms of rescue action of amlodipine in the murine model of iron overload, characterize changes in human cardiac tissue due to IOC, and compare them to the changes in the animal model of IOC.

Methods and results

As an animal model, we used male hemojuvelin knockout (HJVKO) mice, which lacked hemojuvelin (a co-receptor protein for hepcidin expression). The mice were fed a high-iron diet from 4 weeks to 1 year of age. As a rescue, iron-fed mice received the Ca2+ channel blocker, amlodipine, from 9 to 12 months. Iron overload resulted in systolic and diastolic dysfunctions and changes in the cardiac tissue similar to the changes in the explanted human heart with IOC. An IOC patient (β-thalassemia) with left-ventricular ejection fraction (LVEF) 25% underwent heart transplantation. The murine model and the explanted heart showed intra-myocyte iron deposition, fibrosis, hypertrophy, oxidative stress, remodeling of Ca2+ cycling proteins, and metabolic kinases typical of heart failure. Single-myocyte contractility and Ca2+ release were diminished in the murine model. The amlodipine-treated group exhibited normalization of cellular function and reversed fibrosis, hypertrophy, oxidative stress, and metabolic remodeling. We also report a clinical case of primary hemochromatosis successfully treated with amlodipine.

Conclusions

The aged HJVKO murine model on the iron-rich diet reproduced many features of the human case of IOC. The use of amlodipine in the murine model and clinical case reversed IOC remodeling, demonstrating that amlodipine is effective adjuvant therapy for IOC.