bluuebunny/crossref_metadata_2025 huggingface dataset:
Probiotic Mechanisms Affecting Glucose Homeostasis: A Scoping Review
Authors: Pintarič Maša , Langerholc Tomaž
Published: August 2022

The maintenance of a healthy status depends on the coexistence between the host organism and the microbiota. Early studies have already focused on the nutritional properties of probiotics, which may also contribute to the structural changes in the gut microbiota, thereby affecting host metabolism and homeostasis. Maintaining homeostasis in the body is therefore crucial and is reflected at all levels, including that of glucose, a simple sugar molecule that is an essential fuel for normal cellular function. Despite numerous clinical studies that have shown the effect of various probiotics on glucose and its homeostasis, knowledge about the exact function of their mechanism is still scarce. The aim of our review was to select in vivo and in vitro studies in English published in the last eleven years dealing with the effects of probiotics on glucose metabolism and its homeostasis. In this context, diverse probiotic effects at different organ levels were highlighted, summarizing their potential mechanisms to influence glucose metabolism and its homeostasis. Variations in results due to different methodological approaches were discussed, as well as limitations, especially in in vivo studies. Further studies on the interactions between probiotics, host microorganisms and their immunity are needed.
An Integral Sliding Mode Stator Current Control for Industrial Induction Motor
Authors: Shiravani Fahimeh , Alkorta Patxi , Cortajarena Jose Antonio , Barambones Oscar
Published: August 2022

An integral sliding mode control (ISMC) for stator currents of the induction motor (IM) is developed in this work. The proposed controller is developed in the d-q synchronous reference frame, by using the indirect field-oriented control (FOC) method. Robust asymptotic tracking of stator current components in the presence of model uncertainties and current coupling disturbance terms has been guaranteed by using an enhanced ISMC surface. More precisely, the stationary error of stator currents has been eliminated, and the accuracy of the regulators has been enhanced. According to the Lyapunov approach, it has been proven that the stator currents tracking happens asymptotically, and consequently, the stability of each loop has been demonstrated. Simulation and experimental results show the capability of the new controller in diminishing system chattering and increasing the robustness of the designed scheme, considering the variation of the plant parameters and current disturbance terms. It has been illustrated that compared with the conventional ISMC and PI regulators, the proposed current controllers provide smoother control actions and excellent dynamics. In addition, because of the precise control over the rotor flux, the rotor flux weakening method is employed to run the motor at a higher speed than the rated value.
Convexity, Markov Operators, Approximation, and Related Optimization
Authors: Olteanu Octav
Published: August 2022

The present review paper provides recent results on convexity and its applications to the constrained extension of linear operators, motivated by the existence of subgradients of continuous convex operators, the Markov moment problem and related Markov operators, approximation using the Krein–Milman theorem, related optimization, and polynomial approximation on unbounded subsets. In many cases, the Mazur–Orlicz theorem also leads to Markov operators as solutions. The common point of all these results is the Hahn–Banach theorem and its consequences, supplied by specific results in polynomial approximation. All these theorems or their proofs essentially involve the notion of convexity.
New Three-Finger Protein from Starfish Asteria rubens Shares Structure and Pharmacology with Human Brain Neuromodulator Lynx2
Authors: Paramonov Alexander S. , Shulepko Mikhail A. , Makhonin Alexey M. , Bychkov Maxim L. , Kulbatskii Dmitrii S. , Chernikov Andrey M. , Myshkin Mikhail Yu. , Shabelnikov Sergey V. , Shenkarev Zakhar O. , Kirpichnikov Mikhail P. , Lyukmanova Ekaterina N.
Published: August 2022

Three-finger proteins (TFPs) are small proteins with characteristic three-finger β-structural fold stabilized by the system of conserved disulfide bonds. These proteins have been found in organisms from different taxonomic groups and perform various important regulatory functions or act as components of snake venoms. Recently, four TFPs (Lystars 1–4) with unknown function were identified in the coelomic fluid proteome of starfish A. rubens. Here we analyzed the genomes of A. rubens and A. planci starfishes and predicted additional five and six proteins containing three-finger domains, respectively. One of them, named Lystar5, is expressed in A. rubens coelomocytes and has sequence homology to the human brain neuromodulator Lynx2. The three-finger structure of Lystar5 close to the structure of Lynx2 was confirmed by NMR. Similar to Lynx2, Lystar5 negatively modulated α4β2 nicotinic acetylcholine receptors (nAChRs) expressed in X. laevis oocytes. Incubation with Lystar5 decreased the expression of acetylcholine esterase and α4 and α7 nAChR subunits in the hippocampal neurons. In summary, for the first time we reported modulator of the cholinergic system in starfish.
Processing, Microstructure, and Mechanical Properties of Laser Additive Manufactured Ti2AlNb-Based Alloy with Carbon, Boron, and Yttrium Microalloying
Authors: Polozov Igor , Gracheva Anna , Popovich Anatoly
Published: August 2022

In this work, Ti-22Al-23Nb-0.8Mo-0.3Si-0.4C-0.1B-0.2Y (at. %) alloy powder was used to fabricate the Ti2AlNb-based alloy samples using Laser powder bed fusion (L-PBF) Additive Manufacturing with a high-temperature substrate preheating. L-PBF process parameters, including laser power, scan speed, hatching distance, and preheating temperature, allowing for obtaining fully dense (99.9% relative density) crack-free samples, were determined. The effects of substrate preheating temperature during the L-PBF process on microstructure, phase composition, and properties of the obtained Ti2AlNb-based alloy were investigated using X-ray diffraction, scanning electron microscopy, electron backscatter diffraction analysis, and microhardness testing. The results obtained for the material with C, B, and Y microalloying were compared to the Ti2AlNb-based alloy fabricated by L-PBF from the powder not alloyed with C, B, and Y. The results revealed that the microalloying reduced the number of solidification cracks; however, no significant microstructural changes were observed, and high-temperature substrate preheating was still necessary to suppress cold cracking of the alloy. The microstructure of the alloy varied from fully-β/B2, B2 + O, to fully-O depending on the preheating temperature. Effects of hot isostatic pressing and heat treatment conditions on microstructure and mechanical properties were investigated.
Real and Imaginary Impedance Prediction of Ni-P Composite Coating for Additive Manufacturing Steel via Multilayer Perceptron
Authors: Zulkifli Mohammad Fakhratul Ridwan , Roslan Nur Faraadiena , Mat Jusoh Suriani , Mohd Ghazali Mohd Sabri , Abdullah Samsuri , Wan Nik Wan Mohd Norsani
Published: August 2022

Mathematical models are beneficial in representing a given dataset, especially in engineering applications. Establishing a model can be used to visualise how the model fits the dataset, as was done in this research. The Levenberg–Marquardt model was proposed as a training algorithm and employed in the backpropagation algorithm or multilayer perceptron. The dataset obtained from a previous researcher consists of electrochemical data of uncoated and coated additive manufacturing steel with Ni-P at several testing periods. The model’s performance was determined by regression value (R) and mean square error (MSE). It was found that the R values for non-coated additive manufacturing steel were 0.9999, 1, and 1, while MSE values were 1.14 × 10−6, 2.99 × 10−7, and 5.10 × 10−7 for 0 h, 288 h, and 572 h, respectively. Meanwhile, the R values for the Ni-P coated additive manufacturing steel were 1, 1, 1, while the MSE values were 1.06 × 10−7, 1.15 × 10−8, and 6.59 × 10−8 for 0 h, 288 h, and 572 h, respectively. The high R and low values of MSE emphasise that this training algorithm has shown good accuracy. The proposed training algorithm provides an advantage in processing time due to its ability to approach second-order training speed without having to compute the Hessian Matrix.
Coxsackievirus Infection and Associated Diseases
Authors: Nekoua Magloire Pandoua , Hober Didier
Published: August 2022

Coxsackieviruses (CV) are ubiquitous and widespread single-stranded RNA viruses belonging to the Picornaviridae family and the genus Enterovirus, which also includes poliovirus (PV), the best known of the enteroviruses (EV) [...]
ITS rDNA Barcodes Clarify Molecular Diversity of Aquatic Hyphomycetes
Authors: Franco-Duarte Ricardo , Fernandes Isabel , Gulis Vladislav , Cássio Fernanda , Pascoal Cláudia
Published: August 2022

Aquatic hyphomycetes are key microbial decomposers of allochthonous organic matter in freshwater ecosystems. Although their importance in carbon flow and food webs in streams is widely recognized, there are still gaps in our understanding of their molecular diversity and distribution patterns. Our study utilized the growing database of ITS rDNA barcodes of aquatic hyphomycetes (1252 sequences) and aimed to (i) produce new barcodes for some lesser-known taxa; (ii) clarify the taxonomic placement of some taxa at the class or order level, based on molecular data; and (iii) provide insights into the biogeographical origins of some taxa. This study increased the number of aquatic hyphomycete species with available ITS barcodes from 119 (out of ~300 species described) to 136. Phylogenetically, the 136 species were distributed between 2 phyla, 6 classes, and 10 orders of fungi. Future studies should strive to increase the database of ITS sequences, especially focusing on species with unclear phylogenetic relationships (incertae sedis) and with few sequences available. The geographical distribution of species with available ITS sequences included 50 countries from five continents, but 6 countries had more than 20 species associated, showing a bias toward the northern hemisphere, likely due to sampling bias.
Concentrations of Essential Trace and Toxic Elements Associated with Production and Manufacturing Processes in Galician Cheese
Authors: de Oliveira Filho Emanuel Felipe , Miranda Marta , Ferreiro Tania , Herrero-Latorre Carlos , Castro Soares Pierre , López-Alonso Marta
Published: August 2022

The objective of this study was to determine the trace element composition and the toxic metal residues in Galician cow’s milk cheese produced in different systems (artisan, industrial, and organic). Fourteen elements (As, Cd, Co, Cr, Cu, Fe, Hg, I, Mn, Mo, Ni, Pb, Se, and Zn) were determined in 58 representative samples of Galician cheeses by inductively coupled plasma mass spectrometry. The toxic elements were present at low concentrations, similar to those reported for other unpolluted geographical areas. The essential elements were also within the normal range in cheeses. There were no statistically significant differences between smoked and unsmoked cheeses for any of the elements. Chemometric analyses (principal component analysis and cluster analysis) revealed that the industrial cheeses produced in Galicia using the milk from intensive dairy farms were different, in terms of elemental content, from artisan and organic cheeses, in which the elemental contents were similar.
Classification of Japanese Pepper (Zanthoxylum piperitum DC.) from Different Growing Regions Based on Analysis of Volatile Compounds and Sensory Evaluation
Authors: Yamasaki Kazuaki , Fukutome Nami , Hayakawa Fumiyo , Ibaragi Nobuo , Nagano Yukio
Published: August 2022

The Japanese pepper (Zanthoxylum piperitum DC.) is an attractive plant that is highly palatable and benefits human health. There are several lineages of pepper plants in Japan. However, the classification of each lineage by analyzing its volatile compounds and studies on the effects of differences in volatile compounds on human flavor perception have not been performed in detail. Herein, we conducted gas chromatography (GC) and GC/mass spectrometry (GC/MS) analysis of volatile compounds and sensory evaluation of flavor by an analytical panel using 10 commercially available dry powdered Japanese pepper products from different regions. GC and GC/MS analysis detected limonene, β-phellandrene, citronellal, and geranyl acetate as the major volatile compounds of Japanese peppers. The composition of volatile compounds showed different characteristics depending on the growing regions, and cluster analysis of composition classified the products into five groups. The sensory evaluation classified the products into four groups, and the results of both classifications were in good agreement. Our results provide an important basis for proposing cooking and utilization methods that take advantage of the unique characteristics of each lineage based on scientific evidence.
Metabolic Profile of Agropyron repens (L.) P. Beauv. Rhizome Herbal Tea by HPLC-PDA-ESI-MS/MS Analysis
Authors: Bortolami Martina , Di Matteo Paola , Rocco Daniele , Feroci Marta , Petrucci Rita
Published: August 2022

Agropyron repens (L.) P. Beauv. (couch grass) is a world-wide infesting rhizomatous plant with pharmacological applications. Chemical research is focused on its allelopathic and anti-inflammatory components, which are mainly present in the essential oil. Conversely, the aqueous extracts have been sparingly investigated, although the herbal tea is by far the most used formulation. To fill the gap, the metabolic profile of Agropyron repens rhizome herbal tea was investigated by electrospray ionization (ESI) tandem–mass spectrometry (MS/MS); the phenolic profile was investigated by HPLC-PDA-ESI-MS/MS. ESI-MS fingerprinting was provided, evidencing diagnostic ions for saccharides, organic acids and amino acids. The HPLC-PDA-ESI-MS/MS analysis evidenced at least 20 characteristic phenolic compounds, the most representative being caffeoyl and feruloyl quinic esters, followed by coumaric, caffeic and ferulic acids, and hesperidin among flavonoids. In addition, the essential amino acid tryptophan was identified for the first time. The results suggest new perspectives of applications for Agropyron repens rhizome.
An Overview of PDE4 Inhibitors in Clinical Trials: 2010 to Early 2022
Authors: Crocetti Letizia , Floresta Giuseppe , Cilibrizzi Agostino , Giovannoni Maria Paola
Published: August 2022

Since the early 1980s, phosphodiesterase 4 (PDE4) has been an attractive target for the treatment of inflammation-based diseases. Several scientific advancements, by both academia and pharmaceutical companies, have enabled the identification of many synthetic ligands for this target, along with the acquisition of precise information on biological requirements and linked therapeutic opportunities. The transition from pre-clinical to clinical phase was not easy for the majority of these compounds, mainly due to their significant side effects, and it took almost thirty years for a PDE4 inhibitor to become a drug i.e., Roflumilast, used in the clinics for the treatment of chronic obstructive pulmonary disease. Since then, three additional compounds have reached the market a few years later: Crisaborole for atopic dermatitis, Apremilast for psoriatic arthritis and Ibudilast for Krabbe disease. The aim of this review is to provide an overview of the compounds that have reached clinical trials in the last ten years, with a focus on those most recently developed for respiratory, skin and neurological disorders.
Acetyl-CoA Deficiency Is Involved in the Regulation of Iron Overload on Lipid Metabolism in Apolipoprotein E Knockout Mice
Authors: Luo Gang , Xiang Lu , Xiao Lin
Published: August 2022

The role of dietary iron supplementation in the development of nonalcoholic fatty liver disease (NAFLD) remains controversial. This study aimed to investigate the effect of excess dietary iron on NAFLD development and the underlying mechanism. Apolipoprotein E knockout mice were fed a chow diet, a high-fat diet (HFD), or an HFD containing 2% carbonyl iron (HFD + Fe) for 16 weeks. The serum and liver samples were acquired for biochemical and histopathological examinations. Isobaric tags for relative and absolute quantitation were performed to identify differentially expressed proteins in different groups. Excess dietary iron alleviated HFD-induced NAFLD, as evidenced by significant decreases in serum/the hepatic accumulation of lipids and the NAFLD scores in HFD + Fe-fed mice compared with those in HFD-fed mice. The hepatic acetyl-CoA level was markedly decreased in the HFD + Fe group compared with that in the HFD group. Important enzymes involved in the source and destination of acetyl-CoA were differentially expressed between the HFD and HFD + Fe groups, including the enzymes associated with cholesterol metabolism, glycolysis, and the tricarboxylic acid cycle. Furthermore, iron overload-induced mitochondrial dysfunction and oxidative stress occurred in mouse liver, as evidenced by decreases in the mitochondrial membrane potential and antioxidant expression. Therefore, iron overload regulates lipid metabolism by leading to an acetyl-CoA shortage that reduces cholesterol biosynthesis and might play a role in NAFLD pathogenesis. Iron overload-induced oxidative stress and mitochondrial dysfunction may impair acetyl-CoA formation from pyruvate and β-oxidation. Our study provides acetyl-CoA as a novel perspective for investigating the pathogenesis of NAFLD.
Electrochemical Site-Selective Alkylation of Azobenzenes with (Thio)Xanthenes
Authors: Zhong Qiang , Gao Hui , Wang Pei-Long , Zhou Chao , Miao Tao , Li Hongji
Published: August 2022

Herein, we first report an electrochemical methodology for the site-selective alkylation of azobenzenes with (thio)xanthenes in the absence of any transition metal catalyst or external oxidant. A variety of groups are compatible with this electrochemical alkylation, which furnishes the products in moderate to good yields.
Crystal Structure and Noncovalent Interactions of Heterocyclic Energetic Molecules
Authors: Liu Yan , Fan Jiake , Xue Zhongqing , Lu Yajing , Zhao Jinan , Hui Wenyan
Published: August 2022

Nitrogen-rich heterocyclic compounds are important heterocyclic substances with extensive future applications for energetic materials due to their outstanding density and excellent physicochemical properties. However, the weak intermolecular interactions of these compounds are not clear, which severely limits their widespread application. Three nitrogen-rich heterocyclic compounds were chosen to detect their molecular geometry, stacking mode and intermolecular interactions by crystal structure, Hirshfeld surface, RDG and ESP. The results show that all atoms in each molecule are coplanar and that the stacking mode of the three crystals is a planar layer style. A large amount of inter- and intramolecular interaction exists in the three crystals. All principal types of intermolecular contacts in the three crystals are N···H interactions and they account for 40.9%, 38.9% and 32.9%, respectively. Hydrogen bonding, vdW interactions and steric effects in Crystal c are stronger than in Crystals a and b. The negative ESPs all concentrate on the nitrogen atoms in the three molecules. This work is expected to benefit the crystal engineering of heterocyclic energetic materials.
Synthesis of Halopyrazole Matrine Derivatives and Their Insecticidal and Fungicidal Activities
Authors: Cheng Xingan , He Huiqing , Dong Fangyun , Xu Chunbao Charles , Zhang Hanhui , Liu Zhanmei , Lv Xiaojing , Wu Yuehua , Jiang Xuhong , Qin Xiangjing
Published: August 2022

Matrine is a traditional botanical pesticide with a broad-spectrum biological activity that is widely applied in agriculture. Halopyrazole groups are successfully introduced to the C13 of matrine to synthesize eight new derivatives with a yield of 78–87%. The insecticidal activity results show that the introduction of halopyrazole groups can significantly improve the insecticidal activity of matrine on Plutella xylostella, Mythimna separata and Spodoptera frugiperda with a corrected mortality rate of 100%, which is 25–65% higher than matrine. The fungicidal activity results indicate that derivatives have a high inhibitory effect on Ceratobasidium cornigerum, Cibberella sanbinetti, Gibberrlla zeae and Collectot tichum gloeosporioides. Thereinto, 4-Cl-Pyr-Mat has the best result, with an inhibition rate of 23–33% higher than that of matrine. Therefore, the introduction of halogenated pyrazole groups can improve the agricultural activity of matrine.
Alleviation of Cadmium and Nickel Toxicity and Phyto-Stimulation of Tomato Plant L. by Endophytic Micrococcus luteus and Enterobacter cloacae
Authors: Badawy Ibrahim H. , Hmed Ahmed A. , Sofy Mahmoud R. , Al-Mokadem Alshymaa Z.
Published: August 2022

Cadmium (Cd) and nickel (Ni) are two of the most toxic metals, wreaking havoc on human health and agricultural output. Furthermore, high levels of Cd and Ni in the soil environment, particularly in the root zone, may slow plant development, resulting in lower plant biomass. On the other hand, endophytic bacteria offer great promise for reducing Cd and Ni. Moreover, they boost plants’ resistance to heavy metal stress. Different bacterium strains were isolated from tomato roots. These isolates were identified as Micrococcus luteus and Enterobacter cloacae using 16SrDNA and were utilized to investigate their involvement in mitigating the detrimental effects of heavy metal stress. The two bacterial strains can solubilize phosphorus and create phytohormones as well as siderophores. Therefore, the objective of this study was to see how endophytic bacteria (Micrococcus luteus and Enterobactercloacae) affected the mitigation of stress from Cd and Ni in tomato plants grown in 50 μM Cd or Ni-contaminated soil. According to the findings, Cd and Ni considerably lowered growth, biomass, chlorophyll (Chl) content, and photosynthetic properties. Furthermore, the content of proline, phenol, malondialdehyde (MDA), H2O2, OH, O2, the antioxidant defense system, and heavy metal (HM) contents were significantly raised under HM-stress conditions. However, endophytic bacteria greatly improved the resistance of tomato plants to HM stress by boosting enzymatic antioxidant defenses (i.e., catalase, peroxidase, superoxide dismutase, glutathione reductase, ascorbate peroxidase, lipoxygenase activity, and nitrate reductase), antioxidant, non-enzymatic defenses, and osmolyte substances such as proline, mineral content, and specific regulatory defense genes. Moreover, the plants treated had a higher value for bioconcentration factor (BCF) and translocation factor (TF) due to more extensive loss of Cd and Ni content from the soil. To summarize, the promotion of endophytic bacterium-induced HM resistance in tomato plants is essentially dependent on the influence of endophytic bacteria on antioxidant capacity and osmoregulation.
Automatic Swimming Activity Recognition and Lap Time Assessment Based on a Single IMU: A Deep Learning Approach
Authors: Delhaye Erwan , Bouvet Antoine , Nicolas Guillaume , Vilas-Boas João Paulo , Bideau Benoît , Bideau Nicolas
Published: August 2022

This study presents a deep learning model devoted to the analysis of swimming using a single Inertial Measurement Unit (IMU) attached to the sacrum. Gyroscope and accelerometer data were collected from 35 swimmers with various expertise levels during a protocol including the four swimming techniques. The proposed methodology took high inter- and intra-swimmer variability into account and was set up for the purpose of predicting eight swimming classes (the four swimming techniques, rest, wallpush, underwater, and turns) at four swimming velocities ranging from low to maximal. The overall F1-score of classification reached 0.96 with a temporal precision of 0.02 s. Lap times were directly computed from the classifier thanks to a high temporal precision and validated against a video gold standard. The mean absolute percentage error (MAPE) for this model against the video was 1.15%, 1%, and 4.07%, respectively, for starting lap times, middle lap times, and ending lap times. This model is a first step toward a powerful training assistant able to analyze swimmers with various levels of expertise in the context of in situ training monitoring.
Assessment of Various Machine Learning Models for Peach Maturity Prediction Using Non-Destructive Sensor Data
Authors: Ljubobratović Dejan , Vuković Marko , Brkić Bakarić Marija , Jemrić Tomislav , Matetić Maja
Published: August 2022

To date, many machine learning models have been used for peach maturity prediction using non-destructive data, but no performance comparison of the models on these datasets has been conducted. In this study, eight machine learning models were trained on a dataset containing data from 180 ‘Suncrest’ peaches. Before the models were trained, the dataset was subjected to dimensionality reduction using the least absolute shrinkage and selection operator (LASSO) regularization, and 8 input variables (out of 29) were chosen. At the same time, a subgroup consisting of the peach ground color measurements was singled out by dividing the set of variables into three subgroups and by using group LASSO regularization. This type of variable subgroup selection provided valuable information on the contribution of specific groups of peach traits to the maturity prediction. The area under the receiver operating characteristic curve (AUC) values of the selected models were compared, and the artificial neural network (ANN) model achieved the best performance, with an average AUC of 0.782. The second-best machine learning model was linear discriminant analysis with an AUC of 0.766, followed by logistic regression, gradient boosting machine, random forest, support vector machines, a classification and regression trees model, and k-nearest neighbors. Although the primary parameter used to determine the performance of the model was AUC, accuracy, F1 score, and kappa served as control parameters and ultimately confirmed the obtained results. By outperforming other models, ANN proved to be the most accurate model for peach maturity prediction on the given dataset.
Comparative Study of Measurement Methods for Embedded Bioimpedance Spectroscopy Systems
Authors: Ben Atitallah Bilel , Kallel Ahmed Yahia , Bouchaala Dhouha , Derbel Nabil , Kanoun Olfa
Published: August 2022

Bioimpedance spectroscopy (BIS) is an advanced measurement method for providing information on impedance changes at several frequencies by injecting a low current into a device under test and analyzing the response voltage. Several methods have been elaborated for BIS measurement, calculating impedance with a gain phase detector (GPD), IQ demodulation, and fast Fourier transform (FFT). Although the measurement method has a big influence on the measurement system performance, a systematical comparative study has not been performed yet. In this paper, we compare them based on simulations and experimental studies. To maintain similar conditions in the implementation of all methods, we use the same signal generator followed by a voltage-controlled current source (VCCS) as a signal generator. For performance analysis, three DUTs have been designed to imitate the typical behavior of biological tissues. A laboratory impedance analyzer is used as a reference. The comparison addresses magnitude measurement accuracy, phase measurement accuracy, signal processing, hardware complexity, and power consumption. The result shows that the FFT-based system excels with high accuracy for amplitude and phase measurement while providing the lowest hardware complexity, and power consumption, but it needs a much higher software complexity.
Novel and Simplified Procedure to Test Immunity of Low-Power Voltage Transformers
Authors: Mingotti Alessandro , Peretto Lorenzo , Tinarelli Roberto
Published: August 2022

International technical committees put considerable efforts into the writing process of standards. They always try to find a tradeoff between the rigorous scientific requirements and the practical needs of manufacturers and final users. In addition, researchers keep investigating to improve the existing standards with new procedures, achievements, and findings. The purpose of this work is to contribute to that direction. It introduces a simplified and low-cost procedure to test low-power voltage transformers (LPVTs). The procedure is designed to assess the immunity of LPVTs when subjected to external electric fields. The need for this procedure comes from the existing immunity test, which is efficient but sometimes difficult to implement. The proposed one, instead, is simpler, cheaper, does not require the application of the rated voltage, and can be replicated at all voltage levels. In the paper, the procedure is described and demonstrated with experimental tests. From the results, it is possible to appreciate the validity of the proposed solution and the different ways it could be developed, implemented, and improved.
Sensor-Based Automated Detection of Electrosurgical Cautery States
Authors: Ehrlich Josh , Jamzad Amoon , Asselin Mark , Rodgers Jessica Robin , Kaufmann Martin , Haidegger Tamas , Rudan John , Mousavi Parvin , Fichtinger Gabor , Ungi Tamas
Published: August 2022

In computer-assisted surgery, it is typically required to detect when the tool comes into contact with the patient. In activated electrosurgery, this is known as the energy event. By continuously tracking the electrosurgical tools’ location using a navigation system, energy events can help determine locations of sensor-classified tissues. Our objective was to detect the energy event and determine the settings of electrosurgical cautery—robustly and automatically based on sensor data. This study aims to demonstrate the feasibility of using the cautery state to detect surgical incisions, without disrupting the surgical workflow. We detected current changes in the wires of the cautery device and grounding pad using non-invasive current sensors and an oscilloscope. An open-source software was implemented to apply machine learning on sensor data to detect energy events and cautery settings. Our methods classified each cautery state at an average accuracy of 95.56% across different tissue types and energy level parameters altered by surgeons during an operation. Our results demonstrate the feasibility of automatically identifying energy events during surgical incisions, which could be an important safety feature in robotic and computer-integrated surgery. This study provides a key step towards locating tissue classifications during breast cancer operations and reducing the rate of positive margins.
A Hybrid Price Auction-Based Secure Routing Protocol Using Advanced Speed and Cosine Similarity-Based Clustering against Sinkhole Attack in VANETs
Authors: Pramitarini Yushintia , Perdana Ridho Hendra Yoga , Tran Thong-Nhat , Shim Kyusung , An Beongku
Published: August 2022

In ad-hoc vehicle networks (VANETs), the random mobility causes the rapid network topology change, which leads to the challenge of the reliable data transmission. In this paper, we propose a hybrid-price auction-based secure routing (HPA-SR) protocol using advanced speed and cosine similarity-based (ASCS) clustering to establish a secure route to avoid sinkhole attacks and improve connectivity between nodes. The main features and contributions of the proposed HPA-SR protocol are as follows. First, the HPA-SR protocol is employed by the first- and second-price auctions to avoid sinkhole attacks. More specifically, using the Markov decision process (MDP), each node can select a kind of auction method to establish the secure route by avoiding the sinkhole attack. Second, the advanced speed cosine similarity clustering protocol that is considered as underlying structure is presented to improve the connectivity between nodes. The ASCS is constructed based on the cosine similarity and distance between nodes using the speed and direction of the nodes. The results of the performance show that the proposed HPA-SR protocol can establish the secure route avoiding the sinkhole attack while the proposed ASCS clustering can support the strong connectivity. Besides, the HPA-SR with ASCS protocol can show better performance than the benchmark protocol in terms of the routing delay, packet loss ratio, number of packet loss, and control overhead.
Did the Characteristics of Kosovar Teachers Influence the Results of Students in TIMSS 2019? Findings from the Performance of Kosovar Students in TIMSS 2019
Authors: Latifi Fadil , Latifi Endrit
Published: August 2022

This paper aimed to explore the impact of Kosovar teachers’ characteristics on the performance of fourth-grade students in TIMSS 2019. The paper addressed the characteristics of teachers, demographic, and academics, which are closely related to the overall performance of students. In this research, data from the TIMSS 2019 database were used, for which 4435 Kosovar students were tested, and 192 teachers were surveyed. The findings show that Kosovar students did not perform well in TIMSS 2019. They achieved 444 points in the field of mathematics and 413 points in science (average TIMSS 500 points) and were ranked 49th out of 56 countries participating in the test. Data from the teacher survey show that the characteristics of teachers, such as age, professional development, pre-service education, contemporary approach to teaching, etc., also played an important role in the low-scoring performance of Kosovar students in TIMSS 2019. Students who had a teacher with an average age of 30–60 years had a better performance on the test, achieving a difference of 20 points more, compared to students who had new or older teachers (under 30 years and over 60 years). The lack of professional development of teachers also had a major impact on student performance. On average, 25% of teachers in the last 2 years had attended training in certain areas, while on average 80% of them were willing to attend training programs that would improve the profile of their competencies.
The Mediation and the Role of Lawyers in the Procedure through the Prism of Bulgarian History
Authors: Nedeleva Petya
Published: August 2022

The possibility of resolving conflicts through alternative means is a favorable alternative for the parties, as it has deep roots in Bulgarian history, customs and law. If we turn to the history of Bulgarian law we will find that they are often used as an opportunity to resolve disputes of various kinds. Historically, Bulgarian rulers have personally participated in negotiations to resolve international conflicts – for example, Khan Krum proposed negotiations to avoid or end hostilities with Byzantium. The prince Boris I Michael also showed excellent negotiation skills when accepting Christianity as the state religion. During the Ottoman rule, such conciliatory functions were played by the bodies of the Bulgarian municipalities, the guild organizations and representatives of the spiritual authorities. After the Liberation, this tradition was the basis of the Elderly Judicial Councils, the amicable (conciliatory) courts, whose activity is based on the principles of voluntariness, reconciliation and reaching a mutually beneficial agreement.
WOMENPRENEUR MINDSET HOME INDUSTRY “ANEKA CEMILAN ASYIFAH ” IN THE DISTRICT OF RENGAT
Authors: Putri Meilya Karya
Published: August 2022

This study aims to determine how to develop the mindset of women entrepreneurs. This research is qualitative descriptive field research, because it wants to get a description of the Womenpreneur Mindset in the Home Industry "Aneka Cemilan Asyifah" Rengat District, Indragiri Hulu Regency. The data collection method used is Observation, Interview, Documentation. The Credibility Test used is Extended Observation, Increasing Perseverance, Triangulation, Reference Material, Member Check. The results of this study are 5 (five) Mindset elements, namely Passion, Self Leadership Habits, Creativity Habits, Improvisation Habits, and Self-Efficacy owned by Womenpreneur "Aneka Cemilan Asyifah". The Home Industry entrepreneur "Aneka Cemilan Asyifah" shows that the entrepreneur has the passion to be an entrepreneur according to his hobbies in the culinary business, and sees a business opportunity. Even though there are obstacles, they are still looking for solutions to be able to survive in the culinary business that the entrepreneur is living. Home Industry Entrepreneur "Aneka Cemilan Asyifah" can direct and lead his members or employees, the desire to stay in the culinary business since 2015 is carried out by implementing various strategies assisted by his members. The strategy is to keep the business running for a long time, apart from doing creative promotions through the use of social media, a creativity mindset is also done by creating innovative products that are different from the products that have existed in Rengat. The improvised habit mindset is by producing products that have never existed before using quality materials and improving service to customers by delivering the ordered products to the customer's place. The fifth mindset is also evidenced by the statement submitted by the entrepreneur which shows that being an entrepreneur is of course a boss who can manage his own business without being regulated by others and is caused by having a hobby of cooking, so he wants to become a Womenpreneur or female entrepreneur in the culinary field.
THE EFFECT OF SERVICE QUALITY ON CONSUMER PURCHASE INTEREST IN MAS KORI STORE WITH PRICE AS A MEDIATION VARIABLE
Authors: Hermanto Hermanto
Published: August 2022

This research was conducted at the Mas Kori Store. The purpose of this study was to analyze the effect of service quality on price, service quality on buying interest and price on buying interest and the effect of service quality on consumer buying interest mediated by prices at Mas Kori Stores. Researchers took a sample of 100 people at Mas Kori Store consumers. This sampling method was chosen by random sampling technique at random. The data of this study were analyzed using quantitative methods and all data obtained were processed by path analysis which was operated through the IBM SPSS Version 21 Application and the Sobel Calculator. The results of this study indicate that: (1) Service quality has a positive effect on prices. (2) Service quality has a positive effect on buying interest. (3) Price has a positive effect on buying interest. (4) Price mediates the effect of service quality on buying interest.
ANALYSIS OF UTILIZATION OF GOOGLE CLASSROOM APPLICATION AS A LEARNING MEDIA IN INCREASING LEARNING MOTIVATION EVEN SEMESTER STUDENTS IN ECONOMICS COLLEGE OF INDRAGIRI RENGAT
Authors: Windartini Sry , Hairudin Abdul
Published: August 2022

Economics College of Indragiri Rengat, one of the universities in Riau Province located in the Indragiri Hulu district, in the center of Rengat City. Which is one of the most favorite campuses in the Indragiri Hulu district. Improving the quality of student learning must be accompanied by student learning motivation. Learning is a process of communication between learning, teachers, and teaching materials. It can be said that this form of communication will not work without the help of means to convey messages. Several technology-based applications carry out the online learning process (on a network) and can be used in the learning process, one of which is Google Classroom. The number of students in semester 2 is 459, semester 4 is 389, semester 6 is 349, and semester 8 is 369, while for the whole number of students in even semesters, Economics College of Indragiri Rengat is 1,566 students. The results of the research can be drawn by researchers to conclude that every learning media activity such as online lectures conducted by lecturers at the Economics College of Indragiri Rengat, namely using the Google Classroom Application learning media can motivate students, there are also some using the application. others such as WhatsApp, and Zoom Meeting. Because the Google Classroom Application is more effective.
THE EFFECT OF PROMOTION ON PURCHASE DECISIONS MEDIED ​​BY CONSUMER BUYING INTEREST IN SMALL MEDIUM BUSINESS BANANA AND ONION CHIPS IN RENGAT DISTRICT
Authors: Apriansyah Roky , Hermanto Hermanto , Yusnedi Yusnedi , Warnadi Warnadi , Suwaji Suwaji
Published: August 2022

This research was conducted on Small and Medium Enterprises in Rengat District. The purpose of this study was to determine the effect of promotion on purchasing decisions mediated by buying interest in Small and Medium Enterprises in Rengat District. With the number of samples used as many as 98 respondents. Data processing using IBM SPSS Statistic 21 program. The results of this study indicate that: (1) Promotion has a positive effect on Purchase Interest. (2) Promotion has a positive effect on purchasing decisions. (3) Purchase intention has a positive effect on purchasing decisions. (4) Promotion has an effect on purchasing decisions mediated by buying interest.
PHENOMENOLOGY STUDY OF DIRECT VILLAGE CASH ASSISTANCE (BLTDD) FOR POOR COMMUNITIES AFFECTED BY COVID-19 IN INDRAGIRI HULU DISTRICT
Authors: Yulianda Airine , Dewi Kurnia
Published: August 2022

The purpose of this study was to analyze the effectiveness of providing direct village cash assistance (BLT-DD) covid-19 using measurement indicators in the form of timeliness and accuracy of choice, as well as to analyze the impact caused by the provision of direct village cash assistance (BLT-DD) covid. -19 from an economic and social perspective for the people of Indragiri Hulu Regency. This study uses a descriptive method with a qualitative approach. The results of this study indicate that the data collection process to the distribution of BLT-DD in Indragiri Hulu Regency has been effective in terms of timeliness and accuracy of choice. In addition, the Covid-19 BLT-DD can help the community's economy in the midst of a pandemic
PENGARUH BUDAYA ORGANISASI DAN PENGEMBANGAN KARIR TERHADAP KINERJA PEGAWAI PADA KANTOR PELAYANAN PAJAK PRATAMA SURABAYA WONOCOLO.
Authors: Kurniawati Vivi , Setiadi Pompong Budi
Published: August 2022

In an organization or company, Human Resource Management (HRM) is one element that has a strategic function that supports the success of an organization or company to achieve its goals. The influence of organizational culture and career development in its function, namely managing human resources and providing facilities to these employees in a company will affect employee work behavior which in turn will affect the overall performance of a company. The purpose of this study is to determine the effect of organizational culture on employee performance and the influence of career development on employee performance at the Surabaya Wonocolo Tax Service Office. The instrument of this research used a questionnaire. Samples were taken as many as 50 respondents, employees of the Surabaya Wonocolo Tax Service Office. Analysis and data processing using SPSS. The results of this study indicate that organizational culture has no effect on employee performance, while career development has an effect on employee performance.
PENGARUH KUALITAS PELAYANAN, BRAND EQUITY, DAM KUALITAS PRODUK TERHADAP KEPUASAN PELANGGAN STUDI KASUS PADA OUTLET DEAR SISTERS SIDOARJO
Authors: Risdianto Risdianto , Setiadi Pompong Budi , Rahayu Sri
Published: August 2022

This study aims to determine the effect of service quality, brand equity, and product quality on customer satisfaction. This research was conducted at the Dear Sisters outlet in Sidoarjo, East Java. The research method used in this research is descriptive by using quantitative methods. This study uses primary data, namely the distribution of questionnaires by taking respondents from Dear Sisters outlet customers in the Sidoarjo branch, East Java. This study used random sampling with a total of 50 respondents from the Dear Sisters outlet. The analytical method used is multiple regression analysis which is processed using the SPSS application. The results of this study indicate that the service quality variable has no effect on customer satisfaction, the brand equity variable has a positive effect on customer satisfaction and the product quality variable has no effect on customer satisfaction. And the variables of service quality, brand equity and product quality simultaneously affect customer satisfaction
PENGARUH STRATEGI PEMASARAN, FASILITAS OUTLET DAN HARGA TERHADAP KEPUASAN PELANGGAN STUDI KASUS PADA OUTLET DEAR SISTERS SIDOARJO
Authors: Atmojo Dandi Prasetyo , Setiadi Pompong Budi , Rahayu Sri
Published: August 2022

This study aims to determine the effect of marketing strategy, outlet facilities and prices on customer satisfaction. This research was conducted at the Dear Sisters outlet in Sidoarjo, East Java. The research method used in this research is descriptive by using quantitative methods. This study uses primary data, namely the distribution of questionnaires by taking respondents from the Dear Sisters outlet customers in the Sidoarjo branch, East Java. This study uses random sampling with a total of 50 respondents from Dear Sisters outlet customers. The analytical method used is multiple regression analysis which is processed using the SPSS application. The results of this study indicate that the marketing strategy variable has no effect on customer satisfaction, the outlet facility variable has a positive effect on customer satisfaction and the price variable has no effect on customer satisfaction. And the variables of marketing strategy, outlet facilities, and prices simultaneously affect customer satisfaction.
PENGARUH KOMPENSASI DAN LINGKUNGAN KERJA TERHADAP KINERJA KARYAWAN PT RAJAERBA INDOCHEM
Authors: Fernando Fernando , Nuridin Nuridin
Published: August 2022

The purpose to determine the effect of compensation and work environment on employee performance PT. Rajaerba Indochem. This research is included in the category of causal associative research using a quantitative approach. The research was conducted by distributing questionnaires to 35 respondents, all of whom were employees of Rajaerba Indochem. The research method using partially and simultaneous linear regression analysis. The results of the study indicate that simultaneous or partially, compensation and work environment have a positive and significant effect on employee performance PT. Rajaerba Indochem
NILAI PERUSAHAAN DIPENGARUHI KEBIJAKAN DEVIDEN DAN KUALITAS LABA (Studi kasus Industri Sub Sektor Otomotif dan Komponennya periode 2016-2019)
Authors: Puspitaningtyas Ayu
Published: August 2022

This study aims to find out how (1) the simultaneous influence devidend policy and earning quality on value of the company of automotive and componens companies, (2) the partial influence of influence devidend policy and earing quality on value of the company of automotive and components companies in the period 2016-2020. This research uses purposive sampling in taking data. The data collected will be analyzed using multiple linear analysis. The result of this research is (1) there is positive significant influence from dividend policy to value of the company, (2) there is negative significant influence from earning quality variable to value of the company, (3) there is a significant effect of dividend policy and earing quality value addedon value of the company simultaneously.
PENGARUH MANAJEMEN MUTU TERPADU DAN MANAJEMEN RANTAI PASOKAN TERHADAP KINERJA OPERASIONAL PT. BERKAT JAYA MAKMUR ABADI
Authors: Regar Mario Yehezkiel , Rachmarwi Wiwik
Published: August 2022

This study aims to analyze and determine the effect of total quality management and supply chain management on operational performance. The sample used a non-probability sampling method, and the data collected was obtained by means of a questionnaire. It was then analyzed using a quantitative method. The results showed that, together, total quality management and supply chain management have a partial and simultaneous effect on operational performance at PT. Berkat Jaya Makmur Abadi.