bluuebunny/crossref_metadata_2025 huggingface dataset:
Long-term in toto cell tracking using lightsheet microscopy of the zebrafish tailbud
Authors: Fulton Timothy , Lenz Martin O. , Muresan Leila , Lancaster Courtney , Horton Elizabeth , Steventon Benjamin
Published: December 2018

In toto light-sheet imaging allows the tracking of entire growing tissues with high spatial and temporal resolution for many hours. However, this technology requires a sample to be immobilised to ensure that the tissue of interest remains within the field of view throughout the image acquisition period. We have developed a method of mounting and image capture for long-term light-sheet imaging of a growing zebrafish tailbud from the 18 somite stage through to the end of somitogenesis. By tracking the global movement of the tailbud during image acquisition and feeding this back to the microscope stage, we are able to ensure that the growing tissue remains within the field of view throughout image acquisition. Here, we present three representative datasets of embryos in which all nuclei are labelled and tracked until the completion of somitogenesis.
The ‘ALSPAC in London’ dataset: adiposity, cardiometabolic risk profiles, and the emerging arterial phenotype in young adulthood
Authors: Chiesa Scott T. , Rapala Alicja , Charakida Marietta , Wade Kaitlin H. , Timpson Nicholas J. , Deanfield John E.
Published: December 2018

Rising rates of adiposity in the young pose one of the greatest threats to future population burden of cardiovascular disease. Understanding the contribution of genetic and early-life influences to adiposity profiles in young adulthood – when the first signs of subclinical cardiovascular disease commonly appear – are vital if effective lifetime prevention strategies are to be developed. This data note documents the extensive range of genotypic and phenotypic data available from a London-based sub-study of the long-running Avon Longitudinal Study of Parents and Children (ALSPAC)—the ‘ALSPAC in London’ Study—in which extensive adipose and cardiovascular phenotyping was carried out in participants recruited based on a genetic predisposition to obesity.
High malaria transmission sustained by Anopheles gambiae s.l. occurring both indoors and outdoors in the city of Yaoundé, Cameroon
Authors: Doumbe-Belisse Patricia , Ngadjeu Carmene Sandra , Sonhafouo-Chiana Nadege , Talipouo Abdou , Djamouko-Djonkam Landre , Kopya Edmond , Bamou Roland , Toto Jean Claude , Mounchili Souleyman , Tabue Raymond , Awono-Ambene Parfait , Wondji Charles Sinclair , Njiokou Flobert , Antonio-Nkondjio Christophe
Published: December 2018

Background:Malaria remains a major public health problem in Cameroon; however, despite reports on the adaptation of anopheline species to urban habitats, there is still not enough information on malaria transmission pattern in urban settings. In the frame of a larval control trial in the city of Yaoundé, we conducted baseline surveys to assess malaria transmission dynamics in this city.

Methods:Adult mosquitoes were collected indoors and outdoors using CDC light traps and human landing catches from March 2017 to March 2018 in 30 districts of Yaoundé, Cameroon. Mosquitoes were sorted by genus and identified to the species level using PCR. The TaqMan method and ELISA were used to determine mosquito infection status toPlasmodium. Bioassays were conducted to assess femaleAnopheles gambiaesusceptibility to insecticides.

Results:A total of 218,991 mosquitoes were collected. The main malaria vectors were An.gambiaes.l. (n=6154) andAn. funestuss.l. (n=229). Of the 1476An. gambiaes.l. processed by PCR, 92.19% wereAn. coluzziiand 7.81%An. gambiae.An. funestuss.l. was composed of 93.01% (173/186)An. funestusand 4.84% (13/186)An. leesoni. The average biting rate of anopheline was significantly high outdoor than indoor (P=0.013). Seasonal variation in mosquito abundance and biting rate was recorded. The infection rate byPlasmodium falciparumwas 2.13% (104/4893 mosquitoes processed). The annual entomological inoculation rate was found to vary from 0 to 92 infective bites/man/year (ib/m/y). Malaria transmission risk was high outdoor (66.65 ib/m/y) compared to indoor (31.14 ib/m/y).An. gambiaes.l. was found highly resistant to DDT, permethrin and deltamethrin. High prevalence of the West Africakdrallele 1014F was recorded and this was not found to influenceAn. gambiaes.l. infection status.  

Conclusion: The study suggests high malaria transmission occurring in the city of Yaoundé and call for immediate actions to improve control strategies.
How Does Nature Accomplish Spooky Action at a Distance?
Authors: Bhaumik Mani L.
Published: December 2018

The enigmatic nonlocal quantum correlation that was famously derided by Einstein as "spooky action at a distance" has now been experimentally demonstrated to be authentic. The quantum entanglement and nonlocal correlations emerged as inevitable consequences of John Bell's epochal paper on Bell's inequality. However, in spite of some extraordinary applications as well as attempts to explain the reason for quantum nonlocality, a satisfactory account of how Nature accomplishes this astounding phenomenon is yet to emerge. A cogent mechanism for the occurrence of this incredible event is presented in terms of a plausible quantum mechanical Einstein–Rosen bridge.Quanta 2018; 7: 111–117.
Haematopoietic stem cell transplants: principles and indications
Authors: Balassa Katalin , Danby Robert , Rocha Vanderson
Published: December 2018

Haematopoietic stem cell transplantation was proposed as a treatment strategy just over 60 years ago. Owing to great advances in the field, haematopoietic stem cell transplantation has become an established method for the treatment of many haemato-oncological, immunological and hereditary conditions with the potential of cure. The number of haematopoietic stem cell transplants performed worldwide reached one million by 2012. This review provides an overview of autologous and allogeneic haematopoietic stem cell transplantation including disease indications, the individual steps of the procedure and outcome, and highlights achievements in the treatment of autoimmune diseases. Although autoimmune conditions account for only 1% of indications for autologous haematopoietic stem cell transplant, this is increasingly used to treat high-risk autoimmune diseases. Haematopoietic stem cell transplantation can induce long-term remission by resetting the immune system via eradication of autoreactive immune cells and the generation of a de novo self-tolerant immune system. Data seem most encouraging in multiple sclerosis and systemic sclerosis and it is likely that the number of procedures performed to treat these conditions will rise in the future.
Multimodal Medical Image Fusion using Guided Filter in NSCT Domain
Authors: Mehta Nancy , Budhiraja Sumit
Published: December 2018

Multimodal medical image fusion aims at minimizing the redundancy and collecting the relevant information using the input images acquired from different medical sensors. The main goal is to produce a single fused image having more information and has higher efficiency for medical applications. In this paper modified fusion method has been proposed in which NSCT decomposition is used to decompose the wavelet coefficients obtained after wavelet decomposition. NSCT being multidirectional,shift invariant transform provide better results.Guided filter has been used for the fusion of high frequency coefficients on account of its edge preserving property. Phase congruency is used for the fusion of low frequency coefficients due to its insensitivity to illumination contrast hence making it suitable for medical images. The simulated results show that the proposed technique shows better performance in terms of entropy, structural similarity index, Piella metric. The fusion response of the proposed technique is also compared with other fusion approaches; proving the effectiveness of the obtained fusion results.
Prevalence and Antibiotic Resistance of Bacteria Isolated from Urinary Tract Infections of Pregnant Women in Baghdad Hospitals
Authors: Ghaima Kais Kassim , Khalaf Zainab Shaban , Abdulhassan Alaa Aziz , Salman Noor Yahya
Published: December 2018

The aim of this study was investigating the drug resistance patterns of bacteria isolated from pregnant women with urinary tract infections (UTIs). This study included 1140 pregnant women attending two of main hospitals in Baghdad, Iraq, between September 2016 and August 2017. The isolation and identification of uropathogenic bacteria conducted by standard microbiological methods and Vitek2 system. The disc diffusion test was used to determine the antimicrobial resistance patterns of the isolated bacteria. The present study revealed that three hundred and fifty six isolates were positive for significant bacterial growth. Escherichia coli were the predominant bacteria (34 %) followed by Staphylococcus aureus (22.2 %), Klebsiella spp. (14.6 %), non-coagulase Staphylococcus (11.5 %), Proteus spp. (4.5 %), Pseudomonas spp. (3.7 %), Acinetobacter spp. (2.8 %), Citrobacter (2.8 %), Enterococcus (2.5 %) and Enterobacter (1.4 %). High resistance to Ampicillin (85.6 %), Co-trimoxazole (72.2 %) and Tetracycline (71.3 %) was observed. Also, It was found a moderate resistance to Ceftazidime, Ciprofloxacin, Amoxicillin-clavulanic acid and Ceftriaxone. Imipenem was the most active antibiotic against isolated uropathogens. Among the 356 uropathogenic isolates, 196 (55 %) were from women in the 21 to 30 years old age group, and this rate was higher than other age groups. In conclusion, urinary tract infections are frequent among pregnant women. Early detection and continuous monitoring of antibiotic resistance pattern is very important to determine the appropriate treatment of UTIs among pregnant women without complications.
Mouse embryo Hox gene enhancers assayed in cell culture: Hoxb4, b8 and a7 are activated by Cdx1 protein
Authors: Gaunt Stephen J.
Published: December 2018

Mouse Hox gene enhancer elements have typically been identified and characterized using Hox/lacZ transgenic mouse embryos. Such studies have, for example, identified Cdx responsive binding motifs in the enhancers of Hoxb8 and Hoxa7. Production of transgenic mouse embryos involves issues of cost, welfare, and considerable technical skill. It would be of benefit if these studies could be performed, or advanced, in cell culture. It is shown here that Cdx1 activation of mouse Hoxb4, b8 and a7 embryo-active enhancers can be detected using a HepG2 cell culture model system. The technique employed uses co-transfection of an inducible Cdx1 expression construct together with a Hox enhancer/luciferase reporter construct. Cultures to be compared receive identical DNAs and differ only in whether or not they also receive inducer (doxycycline). Response of all three Hox enhancers to Cdx1 protein is inhibited by mutation of Cdx binding motifs which are conserved in sequence from fish or Xenopus to mammals. The magnitude of transfected chick Hoxa7 activation by Cdx1 is increased by multiple copies of its enhancer, but for maximum effect these must contain intact Cdx binding motifs. Cdx1 protein was found not to activate Hoxb4, b8 or a7 enhancers in P19 mouse pluripotential cells.
The remote transcriptional control of Hox genes
Authors: Gentile Claudia , Kmita Marie
Published: December 2018

Since the discovery by Ed Lewis that the order of Hox genes on the chromosome reflects the partitioning of their patterning function along the anterior-posterior axis of the developing fruit fly embryo, extensive efforts have been dedicated to uncovering the regulatory events underlying the collinear expression of Hox genes. These studies have revealed various aspects of Hox regulation, including short-range and long-range transcriptional enhancers, insulator elements and non-coding RNAs. With the development of technologies allowing for high resolution probing of chromatin architecture, notably Chromosome Conformation Capture (3C)-based techniques, a clear relationship is emerging between long-range regulation of Hox genes and the three-dimensional organization of the genome. Here, we provide an overview of these studies and in particular we discuss the functional relevance of genome compartmentalization, CTCF- mediated insulation and the Polycomb Repressive Complexes in the remote control of Hox genes.
Role of Hox genes in regulating digit patterning
Authors: Pérez-Gómez Rocío , Haro Endika , Fernández-Guerrero Marc , Bastida María F. , Ros María A.
Published: December 2018

The distal part of the tetrapod limb, the autopod, is characterized by the presence of digits. The digits display a wide diversity of shapes and number reflecting selection pressure for functional adaptation. Despite extensive study, the different aspects of digit patterning, as well as the factors and mechanisms involved are not completely understood. Here, we review the evidence implicating Hox proteins in digit patterning and the interaction between Hox genes and the Sonic hedgehog/Gli3 pathway, the other major regulator of digit number and identity. Currently, it is well accepted that a self-organizing Turing-type mechanism underlies digit patterning, this being understood as the establishment of an iterative arrangement of digit/interdigit in the hand plate. We also discuss the involvement of 5’ Hox genes in regulating digit spacing in the digital plate and therefore the number of digits formed in this self-organizing system.
HOX genes in normal, engineered and malignant hematopoiesis
Authors: Collins Emma M. , Thompson Alexander
Published: December 2018

Advanced technologies and models systems are improving our understanding of developmental processes. A primary example, hematopoiesis, classically represented by a hierarchical tree with a stem cell at the apex and more lineage restricted cells following each bifurcation has recently been shown to be capable of more adaptable fate decisions. Future research will identify key molecules underpinning this more adaptable or continuous model of hematopoiesis potentially leading to improved engineering of blood cells and therapies for malignant disease. The spatio-temporal, cell specific and exquisite reliance on gene dosage attributed to the HOX family promoted them as candidate master regulators of hierarchical hematopoiesis. Recent discoveries in the need to stimulate or retain HOX expression during engineered human hematopoiesis, supported by similar studies in mice and other developmental models, reinforces their importance at the single cell level. Likewise, dysregulation of HOX in single cells can result in blood cancers such as leukemia. It will be of interest to see what additional roles HOX family members and their regulators including morphogens, epigenetic modifiers and noncoding RNAs play in this evolving field and if these master regulators can be further harnessed for clinical benefit.
HOXA5 protein expression and genetic fate mapping show lineage restriction in the developing musculoskeletal system
Authors: Holzman Miriam A. , Bergmann Jenna M. , Feldman Maya , Landry-Truchon Kim , Jeannotte Lucie , Mansfield Jennifer H.
Published: December 2018

HOX proteins act during development to regulate musculoskeletal morphology. HOXA5 patterns skeletal structures surrounding the cervical-thoracic transition including the vertebrae, ribs, sternum and forelimb girdle. However, the tissue types in which it acts to pattern the skeleton, and the ultimate fates of embryonic cells that activate Hoxa5 expression are unknown. A detailed characterization of HOXA5 expression by immunofluorescence was combined with Cre/LoxP genetic lineage tracing to map the fate of Hoxa5 expressing cells in axial musculoskeletal tissues and in their precursors, the somites and lateral plate mesoderm. HOXA5 protein expression is dynamic and spatially restricted in derivatives of both the lateral plate mesoderm and somites, including a subset of the lateral sclerotome, suggesting a local role in regulating early skeletal patterning. HOXA5 expression persists from somite stages through late development in differentiating skeletal and connective tissues, pointing to a continuous and direct role in skeletal patterning. In contrast, HOXA5 expression is excluded from the skeletal muscle and muscle satellite cell lineages. Furthermore, the descendants of Hoxa5-expressing cells, even after HOXA5 expression has extinguished, never contribute to these lineages. Together, these findings suggest cell autonomous roles for HOXA5 in skeletal development, as well as non-cell autonomous functions in muscle through expression in surrounding connective tissues. They also support the notion that different Hox genes display diverse tissue specificities and locations to achieve their patterning activity.
A scientific journey in the garden of the Hox genes: an interview with Jacqueline Deschamps
Authors: Gofflot Françoise , Jeannotte Lucie , Rezsohazy René
Published: December 2018

For this Special Issue of The International Journal of Develomental Biology on Hox genes, the guest editors met Jacqueline Deschamps for an interview about her research career dedicated to understanding how Hox gene expression is initiated, maintained and functionally utilized in the mouse embryo. We describe here her journey through some of the main discoveries which led to our current knowledge about how Hox genes contribute to shaping the animal body plan. This journey was a human adventure also, of more than 30 years, in the light of which Jacqueline Deschamps delivers here messages to the younger generations of scientists.
Hox genes, clusters and collinearity
Authors: Krumlauf Robb
Published: December 2018

This year marks the 40th anniversary of the discovery by Ed Lewis of the property of collinearity in the bithorax gene complex in Drosophila. This landmark work illustrated the need to understand regulatory mechanisms that coordinate expression of homeotic gene clusters. Through the efforts of many groups, investigation of the Hox gene family has generated many fundamental findings on the roles and regulation of this conserved gene family in development, disease and evolution. This has led to a number of important conceptual advances in gene regulation and evolutionary biology. This article presents some of the history and advances made through studies on Hox gene clusters.
FERRARA, SABINA (2016). La parola dell’esilio. Autore e lettore nelle opere di Dante in esilio.
Authors: Marnoto Rita
Published: December 2018

Firenze: Franco Cesati, 364 p.
As mudanças económicas do pós-guerra e a questão alimentar em Portugal: padrões de consumo, tendências sociais e assimetrias regionais
Authors: Pires Leonardo Aboim
Published: December 2018

É praticamente impossível, ao estudar o crescimento económico português entre 1950 e 1973, não mencionar as mudanças sociais. Contudo, a literatura especializada não tem conferido a devida importância aos aspetos relacionados com o quotidiano, e, especificamente com a alimentação no período do Estado Novo. É nosso propósito, com este ensaio, identificar e caracterizar os novos caminhos da vida quotidiana em Portugal no segundo pós-guerra, tentando responder a duas questões principais: como é que o desempenho económico português afetou a indústria alimentar e como a população percecionou as mudanças, construiu alternativas ou manteve certas práticas nas várias regiões do país.
Du “temps qu’il fait” au temps vécu à la Renaissance : Nature, traces, et textes
Authors: Sautman Francesca Canadé
Published: December 2018

Nous examinons quelques textes, principalement du XVIe siècle, d’auteurs et de genres différents, portant sur l’expérience vécue des faits de nature, en particulier, des événements météorologiques. Nous envisageons les formes et les affects par lesquels ces textes consignaient à la mémoire l’expérience quotidienne des intempéries, ou du « temps qu’il fait ». La proximité et l’engagement avec l’environnement naturel, marqué par le temps, sont une autre dimension de cette recherche. La prédiction du temps climatique restant surtout l’apanage des croyances populaires et des pratiques liturgiques, nos textes, sans appartenir aux genres scientifiques reconnus, se placent entre ces deux pôles et font entendre des voix originales concernant le rapport à la nature.
Сливовый галловый клещ Acalitus phloeocoptes (Nalepa, 1890) (Acari, Trombidiformes, Eriophyidae) в Казахстане
Authors: Temreshev I. I. , Kopzhasarov B. K. , Slyamova N. D. , Beknazarova Z. B. , Darubayev A. A.
Published: December 2018

Галловый сливовый клещ Acalitus phloeocoptes (Nalepa, 1890) – опасный вредитель косточковых пород, впервые обнаружен в Казахстане. В 2018 году площадь посадок абрикоса в Алматиснкой области, зараженная им, составила около 150 га. Для локализации вредителя были испытаны различные препараты. В ходе испытаний наиболее высокую эффективность показали варианты: Вертимек к.э. с нормой расхода 1 л/га и Омайт 57 % к.э. - 2 л/га. Они были рекомендованы садоводческим хозяйствам для проведения обработки против вредителя.
Анализ биотопического распределения булавоусых чешуекрылых Нижегородской области (Lepidoptera, Rhopalocera)
Authors: Korb S. K.
Published: December 2018

Рассматривается биотопическое распределение булавоусых чешуекрылых Нижегородской области и его закономерности. Выделено 7 групп биотопов, описаны их фауны. Определены стенотопные виды и виды разной степени эвритопности, определено их соотношение. Определены виды с наибольшим адаптационным потенциалом как наиболее вероятные кандидаты на заселение нетипичных биотопов на данной территории.
Notes on Dolichopodidae (Diptera) from the White Sea coast and islands (Russian North)
Authors: Grichanov I. Ya. , Ovsyannikova E. I.
Published: December 2018

Original data on Dolichopodidae from the Belomorsk district of Karelia and Bolshoi Solovetskii Island (Arkhangelsk Region, Primorskii district) resulted from the short-term visit (2018) are presented. All ten collected species and the genus Medetera are firstly recorded for the Solovetskiye Islands. Dolichopus discifer Stannius, 1831, Dolichopus ungulatus (Linnaeus, 1758), Rhaphium laticorne (Fallén, 1823), Sympycnus pulicarius (Fallén) and Syntormon tarsatus (Fallén, 1823) are new species for the Arkhangelsk Region. Photographs of habitats of dolichopodid species are included.
Стоматоцисты хризофитовых в притоках северной оконечности озера Байкал
Authors: Firsova A. D. , Bessudova A. Yu. , Likhoshway E. V.
Published: December 2018

C помощью сканирующей электронной микроскопии в устьях рек Кичера, Верхняя Ангара, а также в Душкачанском, Среднем и Дагарском устьях Ангаро-Кичерской дельты, обнаружено 58 стоматоцист хризофитовых, из которых 25 описаны как новые.
Чужеродные макробеспозвоночные в донных сообществах Новосибирского водохранилища (эколого-фаунистический обзор)
Authors: Yanygina L. V.
Published: December 2018

Строительство и последующее использование водохранилищ стало ведущим фактором проникновения и распространения чужеродных видов в Обь-Иртышском бассейне. Фауна чужеродных видов Новосибирского водохранилища представлена пятью видами, три из которых (Gmelinoides fasciatus Steb., Micruropus possolskii Sowinsky и Neomysis intermedia (Czerniavsky)) были преднамеренно вселены для повышения кормовой базы водоема, еще два (Viviparus viviparus (L.) и Astacus leptodactylus Eschscholtz) появились в результате непреднамеренных интродукций. Прослежена история проникновения и натурализации каждого вида, проанализированы экологические факторы их обитания, рассмотрены особенности современного пространственного распределения вселенцев. Отмечено, что несмотря на невысокое видовое богатство, вселенцы существенно влияют на структурные характеристики донных сообществ водохранилища.
The fauna and ecology of wasps of the genus Tachysphex Kohl, 1883 (Hymenoptera: Apoidea: Crabronidae) in Nakhchivan Autonomous Republic of Azerbaijan
Authors: Maharramov M. M. , Aliyev Kh. A. , Bayramov A. B.
Published: December 2018

An annotated checklist containing 11 species in five species groups of the wasp genus Tachysphex that occur in the Nakhchivan Autonomous Republic is presented. Five species are recorded from Azerbaijan for the first time: Tachysphex ferrugineus Pulawski, 1967, T. nitidus (Spinola, 1806), T. pompiliformis (Panzer, 1803), T. mocsaryi Kohl, 1884 and T. costae (de Stefani Perez, 1882). Six species are recorded from Nakhchivan AR for the first time: Tachysphex consocius Kohl, 1892, T. fulvitarsis (A. Costa, 1867), T. helveticus Kohl, 1885, T. brevipennis Mercet, 1909, T. pulcher Pulawski, 1967, T. dignus Kohl, 1889. Data on landscape and habitat distributions of each species are given.
Интерпретация ценоморф растений юго-востока Украины в терминах фитоиндикационных шкал
Authors: Zhukov A. V.
Published: December 2018

В работе показана дискретная природа ценоморф растений на примере флоры юго-востока Украины. С помощью дискриминантного анализа показано, что ценоморфы являются дискретными классами видов растений, которые обособлены между собой в большей степени, чем можно предположить исходя из только лишь континуальной природы экологических различий между видами. В качестве предикторов в дискриминантном анализе использованы диапазональные фитоиндикационные шкалы Дидуха и перемасштабированные шкалы Элленберга. Высокий уровень дискриминирующей способности модели, построенной на основе континуальных предикторов, свидетельствует о значительной специфичности видов растений в пределах отдельных ценоморф. Приведен анализ экоморфической структуры ценоморф. Предложена новая ценоморфа – ариданты. Причина компактности ценоморф находится в коадаптации видов растений в пределах каждой ценоморфы, а также в трансформирующем влиянии растительной обстановки на окружение. С помощью метода классификационных деревьев выполнен поиск классификационных правил выделения ценоморф на основе фитоиндикационных шкал. Предложено рассматривать фитоиндикационные шкалы как маркеры биотопа, а ценоморфы – как маркеры экотопа.
Долговременная динамика соотношения взрослых и молодых птиц у ближних и дальних мигрантов на осеннем пролете на Куршской косе Балтийского моря
Authors: Sokolov L. V. , Shapoval A. P.
Published: December 2018

Было проанализировано соотношение взрослых и молодых птиц на осеннем пролете на Куршской косе Балтийского моря у 25 видов ближних и 19 дальних мигрантов в период с 1962 по 2016 гг. Сравнительный анализ показал, что доля взрослых особей среди пойманных в большие ловушки «рыбачинского типа» птиц была значимо выше у ближних мигрантов (19,4%), чем у дальних (5,4%). У видов, совершающих преимущественно дневные миграции, доля взрослых особей была выше, чем у ночных мигрантов (24,3% против 7,4% у ближних мигрантов и 7,4% против 4,5% – у дальних). У подавляющего большинства видов были выявлены значительные межгодовые колебания в соотношении взрослых и молодых особей. Однако значимые долговременные тренды в изменении этого соотношения были выявлены только у 3 видов ближних мигрантов и одного дальнего мигранта. Доля молодых особей, отлавливаемых на осеннем пролете, оказалась значимо связанной со средней температурой воздуха в Балтийском регионе весной и в начале лета (июнь): чем выше была температура в этот период, тем большая доля молодых птиц присутствовала в осенних отловах. Такая связь была выявлена у 8 видов ближних и 2 дальних мигрантов. Мы предполагаем, что это объясняется, в первую очередь, лучшей успешностью размножения этих видов в годы с высокой температурой воздуха весной и в начале лета в исследуемом регионе.
Avian assemblages in lowland and foothill agro-ecosystem in Lesotho
Authors: Kopij G.
Published: December 2018

During the years 1996-2001, the line transect method has been employed to assess the species composition, dominance structure and relative abundance of birds resident in traditional farmlands, in the lowlands (10 transects with the total length of 43.9 km) and foothills (10 transects with the total length of transects 46.5 km) of Lesotho, southern Africa. This has been done to show the role of this farming in biodiversity conservation. A total of 76 resident species have been recorded in farmlands of Lesotho, 62 species in the lowlands and 53 species in the foothills. In the lowland farmlands the dominant group was composed of 6 species, namely the Prinia, Cape Bunting, Cinnamon-breasted Bunting, Cape Canary, Neddicky and Common Quail (35.8 %); in the foothills the group was composed 5 species: Karoo Prinia, Cape-turtle Dove, Laughing Dove, Cape Bunting and Cape Canary (35.9 %). Eighteen species bred in significantly different densities in lowlands and foothills. While insectivorous birds were more numerous in the lowland than foothill, the reverse was true with granivorous birds. Those two guilds comprised together 78% and 83% in the lowland and foothill respectively. The proportion of species in each guild was similar. In the lowland farmland the following eight species were more common that in the foothill farmlands, while in foothill farmland 10 species were more numerous than in lowland farmland. Species diversity and evenness were strikingly high and similar in lowlands and foothills, although Sorensen Similarity Index between these two areas was low (I = 0.44). Both species diversity and structure of dominance in avian communities in Lesotho farmlands indicate that the traditional farming play a positive role in biodiversity conservation.
Bacteria associated with planktonic diatoms from Lake Baikal
Authors: Mikhailov I. S. , Zakharova Y. R. , Volokitina N. A. , Petrova D. P. , Likhoshway Y. V.
Published: December 2018

Algal-bacterial associations were studied in unialgal xenic cultures of Synedra acus subsp. radians, Asterionella formosa and Fragillaria crotonensis planktonic diatoms from Lake Baikal, using epifluorescent and scanning electron microscopy. It was found that rod- and ovoid-shaped bacteria colonized cell walls of diatoms. Cloning and sequencing of fragments of 16S rRNA gene in diatom cultures revealed members of Gammaproteobacteria (Pseudomonas sp.), Betaproteobacteria (Janthinobacterium sp., Hydrogenophaga sp., Methylophilus sp.), Bacteroidetes (Flavobacterium sp., Pedobacter sp.), and Acinobacteria (Nocardioides sp.).
The genus Rosa L. (Rosaceae) in the flora of Nakhchivan Autonomous Republic (Azerbaijan)
Authors: Ibrahimov A. M. , Talibov T. H. , Matsyura A. V.
Published: December 2018

Based on the long-term studies conducted in the Nakhchivan Autonomous Republic (2004-2017) and the literature data, the composition of Rosa L. genus was investigated and its distribution zones were specified. It has become clear that 34 species of hips are spread in the area that, 30 of them are wild, and 4 of them – R. centifolia L., R. chinensis Jacq, R. damascena Mill., R. multiflora Thunb. are used for greenery of parks and gardens in cultivated conditions. In recent years, as a result of the effects of climatic and anthropogenic factors on the territory of the autonomous republic, wild species of Rosa L. genus have been found to be in danger. Therefore, considering their rare and endangered species of Rosa karjaginii Sosn., R. nisami Sosn., R. sosnovskyana Tamamsch., R. rapinii Boiss. & Bal., R. pimpinellifolia L., R. tuschetica Boiss. have been put “Red book” of Nakhchivan Autonomous Republic, Rosa azerbaidzhanica Novopokr. et Rzazade, Rosa karyagini Sosn. və Rosa nisami Sosn. species have been put “Red Book” of Azerbaijan Republic and there have been shown protection ways.
Омела окрашенная (Viscum coloratum (Kom.) Nakai) в Восточной Азии (таксономия, ареал, возможности использования)
Authors: Gorovoy P. G. , Balyshev M. E. , Krylov A. V. , Schekina V. V. , Nizkiy S. E.
Published: December 2018

В работе представлены результаты исследования морфологических признаков и распространения в Восточной Азии Viscum coloratum (Kom.) Nakai с целью выявить специфические признаки этого вида и установить северную и северо-западную границы его ареала. Омела окрашенная на Дальнем Востоке представлена двумя формами: forma lutescens Kitag. и forma rubroaurantiacum (Makino) Kitag. В результате нашего исследования установлено, что северо-западная граница распространения омелы окрашенной достигает в Амурской области долины среднего течения реки Зеи. Впервые отмечается, что на Дальнем Востоке Viscum coloratum произрастает на Quercus mongolica (дуб монгольский). Омела окрашенная обильно поражает деревья липы около лесных пасек и в течение 20 лет заселяет почти все деревья, что вынуждает пчеловодов переносить пасеки в другие места. Среди  распространителей плодов Viscum coloratum преобладают обыкновенные и японские свиристели. В народной медицине стран Восточной Азии омела окрашенная используется при лечении гипертонии и онкологических заболеваний. Основными противоопухолевыми веществами в водном экстракте омелы являются лектины.
Новые находки редких и малоизвестных видов цветковых растений флоры Крыма
Authors: Fateryga V. V. , Fateryga A. V.
Published: December 2018

Приводятся сведения о примечательных находках пяти видов: для охраняемых в Крыму Allium regelianum и Frankenia pulverulenta указаны новые местонахождения на полуострове; подтверждено произрастание в Крыму Ornithogalum arcuatum и Phelipanche arenaria; Tetradiclis tenella найден нами спустя 94 года после предыдущего сбора.
First record of Apatura iris (Linnaeus, 1758) (Lepidoptera: Nymphalidae) from the Republic of Khakassia (South Siberia)
Authors: Dragan S. V.
Published: December 2018

Apatura iris (Linnaeus, 1758) is recorded for the Republic of Khakassia (South Siberia) for the first time.
Proposta de construção de indicador de caracterização da acessibilidade na região metropolitana de Fortaleza
Authors: Holanda de Souza Hélio Henrique , Loureiro Carlos Felipe Grangeiro
Published: December 2018

A compreensão da problemática é essencial na construção de soluções adequadas aos problemas de mobilidade e acessibilidade urbanas. Assim, indicadores que possam caracterizar e diagnosticar estes problemas devem ser melhor investigados. Este trabalho propõe um indicador de caracterização da acessibilidade com base no logsum, comumente utilizado como medida do excedente do consumidor, apresentando características que favorecem seu uso como medida de desempenho do sistema de transportes. Para propor o indicador, utiliza-se como referência uma representação geral da problemática da mobilidade e acessibilidade e uma tipologia de problemas baseada nos princípios da equidade e sustentabilidade, verificando sua aplicabilidade na Região Metropolitana de Fortaleza. Conclui-se que o método proposto permite a estimativa de indicadores adequados para analisar problemas de acessibilidade desde que no cálculo do logsum ponderado, bem como na definição e calibração das funções utilidade, sejam consideradas as especificidades de cada tipo de problema que se pretende caracterizar e diagnosticar.
Gadamer’s Hermeneutics as a Model For the Feminist Standpoint Theory
Authors: DEMİREZEN İsmail
Published: December 2018

This
work which reconstructs Gadamer’s hermeneutics for guiding feminist standpoint
theory consists of five chapters. Firstly, several possible feminist standpoint
theories and their difficulties in addressing how knowledge is situated yet
true are clarified. Secondly, it will be examined that Gadamer’s proposal for
the relevance of the historicity on the reaching to truth. Thirdly, we will
discuss Gadamer’s notion of fusion of horizons as a way to reach to truth.
Fourthly, we will elaborate Wasterling’s critique against Gadamer and some
arguments that Gadamer’s hermeneutics substitutes feminist epistemology for
masculine epistemology.  Finally, this
paper will evaluate Gadamer’s proposal for hermeneutics is appropriate for
feminist standpoint theory, if so, how it is appropriate.
İbn Nübâte El-Hatîb ve Hz. Hüseyin’in Şehâdeti ile İlgili Hutbesi
Authors: GEMİ Ahmet
Published: December 2018

Arap edebiyat tarihinde adından sitayişle bahsedilen hatiplerden biri, İbn Nübâte’dir. 336/946 yılında Diyarbakır’ın Silvan (Meyyâfârikîn/Fârikîn) ilçesinde doğan İbn Nübâte, Hamdânîlerin Emîri Seyfüddevle b. Hamdân’ın (ö. 356/967) himayesinde bulunmuş ve sarayında hatiplik yapmıştır. Silvan ve Halep’te îrâd ettiği hutbelerle hak ettiği üne kavuşan İbn Nübâte’nin günümüze ulaşan hutbe mecmuası bulunmaktadır. İbn Nübâte, 374/984 yılında Silvan’da vefat etmiştir. Bazı kaynaklar Halep’te vefat ettiğini belirtmektedir. İbn Nübâte’nin muharrem ayının ikinci cuma gününe denk gelen hutbede îrâd ettiği Hz. Hüseyin’in şehit edilmesi ile ilgili olan hutbesi önemlidir. İbn Nübâte, bu hutbesinde Hz. Hüseyin’in şehadetinden dolayı üzüntüsünü dile getirmekte ve aynı şekilde Müslümanların da bu olaya üzülmeleri gerektiği üzerinde durmaktadır.
Reseña de Alejandro Eujanian, El pasado en el péndulo de la política. Rosas, la provincia y la nación en el debate político de Buenos Aires, 1852-1861.
Authors: Victorero Nahuel Pablo
Published: December 2018

El periodo que abarca desde la batalla de Caseros hasta el final de la conformación del Estado Nacional (1852-1880) ha sido analizado por la historiografía reciente. Desde el ya clásico Una Nación para el desierto argentino de Tulio Halperin Donghi a los distintos estudios, con múltiples miradas y enfoques, que han puesto en consideración un conjunto de problemáticas propias del periodo signado por el conflicto abierto entre el Estado Federal que buscaba impulsar Urquiza y el modelo de país propio de la provincia de Buenos Aires.
Adiponectin level in diabetic kidney disease the relationship with glycemic control and microvascular complications; a mystery unresolved
Authors: A. E. Tony Effat , H.Mostafa Mohamed , F. Abdelaal Refaat , A. Tony Abeer , El- Shereif Tahra , Adel A. Abdou Madleen
Published: December 2018

Background: Defining new predictive biomarkers in diabetic kidney disease (DKD) would provide a window of opportunity for preventive and/or therapeutic interventions to prevent or delay the onset of irreversible long-term micro and or macro vascular complications. Adiponectin (ADPN) has been variously associated with diabetic microvascular complications; however, no comprehensive clinical data exist examining the association between adipocytokines and the presence of these complications.Aim of study: we aimed to measure the plasma levels of adiponectin in patients with type 2 diabetes mellitus, to assess whether these levels vary with the different stages of DKD according to their e GFR and to evaluate its relation to their microvascular complications and glycemic control.Methods: This is a prospective observational study including 100 T2DM classified into two groups according to their albuminuria levels and estimated GFR. Participants subjected to thorough history taking and clinical examination. Serum level of ADPN was assessed in all patients.Results: Serum ADPN levels were significantly lower in T2DM patients with nephropathy (P = 0.001), while their levels were non-significantly higher in patients with non-proliferative retinopathy or neuropathy. Their levels were lowered with more advanced stages of DKD with nephropathy and the decrement was dependent on their severity (P<0.001). Levels of ADPN with cutoff value of < 22600 (Î¼g/mL) had ability to diagnose microvascular complications in our diabetic patients with sensitivity (81%) and specificity (27%). Multivariate logistic regression analysis showed that the odds ratio for the presence of nephropathy in the lowest tertile of ADPN was 1.09 (95% CI; 11.45- 13.08, P= 0.06), therefore, ADPN was not an independent risk factor for diabetic nephropathy. However, its higher level was independently associated with increased odds for the presence of neuropathy in particular. Conclusions: ADPN plays a role in the pathogenesis of microvasculopathy in diabetic patients and help to identify high-risk patients and modulate the therapeutic potential in the prevention of DKD.Â Â
Estimation of the earth's albedo over some selected area the Republic of Chad
Authors: Marouf BARKA Zakaria , Lealea ThÃ©ophile , Tchinda Rene
Published: December 2018

Surface albedo is one parameter of the climate variables. It influences the surface radiation budget for a given site. The availability of surface albedo data at both temporally and spatially levels are needed. In the lack of ground recorded values of albedo, we have to estimate surface albedo from the climatic variables. The model generated in this study enables the continuous observation of land surface albedo through relative model established from the multivariate regression method. From satellite recorded data, we estimate the ground surface albedo for some selected sites. The result were satisfactory with the root mean square error (RMSE) is 0.035. The Mean Absolute Error (MAE) was computed and indicated to be as low as 0.027 and mean absolute percentage error (MAPE) is 7.58.Â Â
Pomiar efektywności
Authors: Johnes Jill
Published: December 2018

Celem niniejszego rozdziału jest przede wszystkim identyfikacja i przedstawienie różnych metod pomiaru efektywności stosowanych w kontekście oceny funkcjonowania instytucji edukacyjnych w tym szkół wyższych. Ponadto dokonano przeglądu badań empirycznych wykorzystujących te metody na wszystkich poziomach edukacji.
One-photon Absorption Characterizations, Dipole Polarizabilities and Second Hyperpolarizabilities of Chlorophyll a and Crocin
Authors: Karakas A. , Ceylan Y. , Karakaya M. , Taser M. , Terlemez B. B. , Eren N. , El Kouari Y. , Lougdali M. , Arof A. K. , Sahraoui B.
Published: December 2018

The dispersion-free dipole polarizability (α) computations for chlorophyll a (1) and crocin (2) have been achieved by density functional theory (DFT) at B3LYP/ 6-31G(d) level. The measured one-photon absorption (OPA) wavelengths are quite consistence with the theoretically obtained values. Ab-initio quantum chemical calculations (time-dependent Hartree-Fock (TDHF)) have been implemented to reveal the static second hyperpolarizabilities (γ) and dynamic dipole polarizabilities of the title molecules. The examined compounds display γ with non-zero values, introducing their third-order nonlinear optical (NLO) phenomena. The first and second frontier molecular orbitals of the investigated molecules have been also derived from DFT.
The Optical and Crystallite Characterization of Bilayer TiO2 Films Coated on Different ITO layers
Authors: Kutlu Nermin , Oturak Halil
Published: December 2018

Titanium dioxide(TiO2) is a well-known material which is non-toxic with efficient photoactivity, high stability, low-cost and corrosion-resistant. Up to today’s technology, TiO2 films are coated for various applications in the scientific area. In this study, bilayer TiO2 films were coated on indium tin oxide(ITO) layers that have different characteristic properties. The devices designed as homemade of Direct Current Magnetron Sputtering (DCMS) and Spray Pyrolysis Deposition (SPD) coating methods were used to coat the first and second layers of bilayer TiO2 films, respectively. The optical and crystalline characterizations of bilayer TiO2 films were analyzed by UV-VIS spectroscopy and XRD techniques. The XPS spectrum showed that O2 molecules simply oxidize from Ti3+ to Ti4+ after SPD coating method. The characterization results of TiO2 films showed change in optical band gap value and crystalline structure of TiO2 bilayer.
Sonocatalytic degradation of methyl orange in aqueous solution using Fe-doped TiO2 nanoparticles under mechanical agitation
Authors: Song Shoujian , Hao Changchun , Zhang Xianggang , Zhang Qing , Sun Runguang
Published: December 2018

In the present study, the Fe-doped TiO2 modified nanoparticles was successfully synthesized by the combination of the sol-gel method and heat treatment, and the degradation of methyl orange was tested by the combination method of ultrasonic radiation and mechanical agitation. The effects of different factors on the degradation of methyl orange (MO) solution were studied, such as ultrasonic irradiation time, the ultrasonic frequency, the added amount of catalyst, the initial pH value, the initial concentration of methyl orange, and revolutions per minute. The optimal experimental conditions for sonocatalytic degradation of the MO obtained were: ultrasonic irradiation time = 60 min, pH value = 3.0 and revolutions per minute = 500 rpm. By means of response surface analysis, the best fitting conditions were as follows: ultrasonic frequency = 36.02 kHz, added amount of catalyst = 490.50 mg/L, the initial concentration of methyl orange = 9.22 mg/L, and the optimum condition was close to the experimental data by response surface method. Under optimal conditions, the sonocatalytic degradation of MO was 99%. The degradation of MO showed that the combination of Fe-doped modified TiO2 nanoparticles, mechanical agitation and ultrasonic irradiation was discovered that can degrade methyl orange effectively in aqueous solution.
MicroRNA delivery mediated by PEGylated polyethylenimine for prostate cancer therapy
Authors: CY Chen , GY Li , L Zhang , XH Huang , D Cheng , SC Wu , CZ Xu , JH Zhou , L Xun
Published: December 2018

A microRNA (miRNA) nanomedicine PEG-PEI/miR-221/222 was synthesized based on PEGylated polyethylenimine PEG-PEI and used to transfect prostate cancer cells (PC-3) in vitro. Gel retardation assay confirmed the formation of nanomedicine, of which the zeta potential and particle size were determined by dynamic light scattering. Its cytotoxicity was analyzed by CCK-8 assay-while its transfection efficiency was analyzed by flow cytometry. Cell uptake and intracellular distribution of nanoparticles were evaluated using laser confocal microscopy. RT-PCR and western-blot assays were conducted to verify the regulation of SIRT1 target gene. We found that the properties of the nanocomplexes of miRNA and PEG-PEI depended on N/P ratios. At higher N/P ratio, accompanied by higher zeta potential and higher cytotoxicity, PEG-PEI is needed to completely condense the miRNA into small particles with uniform size distribution. Under an N/P ratio of 20, high transfection efficiency and low carrier cytotoxicity were obtained simultaneously in PC-3 cells in vitro. Consequently, the SIRT1 expression was up-regulated due to the nanoparticle-delivered miR-221/222, which resulted in effective inhibition of PC-3 cells. Our study revealed the PEG-PEI/miR-221/222 nanomedicine as a prospective alternative for treatment of advanced prostate cancer and also lays a foundation for future in vivo investigation.
Comparative sulfite assay by voltammetry using Pt electrodes, photometry and titrimetry: Application to cider, vinegar and sugar analysis
Authors: Pisoschi Aurelia Magdalena , Pop Aneta
Published: December 2018

Sulfite is a widely applied preservation agent, against oxidative decay in foodstuffs and beverages. Among the analytical methods applied, electrochemical techniques exploit its facility to undergo oxidation. This paper aims at the comparative investigation of the performances exhibited by three analytical methodologies: cyclic voltammetry at different Pt working electrodes, the volumetric method employing sodium thiosulfate as titrating agent and the photocolorimetric method relying on the reduction of Fe3+-orthophenanthroline complex by sulfite. The cyclic voltammetric assay was performed at Pt strip and Pt ring electrodes, by linearly sweeping the potential between -100 and 1,500 mV. The linear range corresponded to 7.5 mg L-1– 4.0 g L-1for Pt strip working electrode and to 15.5 mg L-1– 4.0 g L-1for Pt ring working electrode. Relative standard deviations smaller than 3% showed repeatability. RSD values smaller than 3% were also obtained in the photometric assay, but the latter was characterised by a narrower linear range. The Pt strip electrode allowed wider linear range and lower sensitivity, whereas the Pt ring electrode with Ag/AgCl reference in the same unit was characterised by better repeatability. Applications involved sulfite assay in vinegar, brown sugar and cider samples with consistency between cyclic voltammetry and titrimetry.