bluuebunny/crossref_metadata_2025 huggingface dataset:
Averroes and St. Thomas Aquinas Debate: How the Moslem Philosopher Understanding Aristotle Philosophy about Soul and Intellect
Authors: Anakot Elka
Published: November 2023

Arabs have penetrated the joints of Europa thought through a process of transliteration involving Islamic philosophers. While medieval Europe was a dark age, Arabs provided opportunities and space for the transliteration of the works of Plato and Aristotle.   Thinkers (Islamic philosophers) penetrated the joints of European thought through the process of transliteration, one of which was Averroes, who attempted to re-perceive the soul and intellect of Aristotle, which later differed from the understanding built by St. Thomas Aquinas. From their position as Islamic philosophers, Averroes and St. Thomas Aquinas as Christian philosophers, their faith interests also enriched the conflict over the understanding of Aristotle's philosophy, especially about soul and intellect.
Association between Diabetes Mellitus and Pancreatic Cancer: A Comprehensive Narrative Review
Authors: Shahid Zeryab , Arif Sehrish , Paliwal Himanika , Baskara Salian Rishabh , Rauf Butt Samia , Choudhry Faiza , Ishola Yetunde , Zain ul Abidin  , Nazir Zahra
Published: November 2023

Pancreatic cancer (PC) is extremely aggressive, with symptoms occurring only in the advanced stage. The relationship between Type 2 Diabetes Mellitus (T2DM) and PC is complex. However, it is unclear whether long-standing diabetes causes cancer or whether cancer proceeds the development of impaired glucose metabolism. PubMed, Google Scholar, Scopus and Cochrane library were consulted to look for relevant literature. We narrowed down 20 articles after implementing inclusion and exclusion criteria. The database was searched using the keywords “Pancreatic Cancer” AND “Diabetes Mellitus.” This narrative literature review aims to analyze the literature on the analysis of the metabolic association of T2DM, the risk of carcinogenesis of the pancreas and their association, and the current understanding of metabolic pathways involved in cellular growth and metabolism. About 80% of patients with pancreatic disease have a previous diagnosis of diabetes within five years. We explored the literature to find metabolic associations between PC and T2DM due to insulin resistance, hyperinsulinemia, hyperglycemia, low-grade chronic inflammation, and insulin-like growth factor axis alteration.
ASSESSMENT OF HEAVY METALS IN READY-TO-EAT (RTE) VEGETABLES SALADS SOLD WITHIN KANO METROPOLIS, NIGERIA
Authors: GARBA M. , DANDAGO M.A. , IGWE E.C , ZUBAIRU I.K.
Published: November 2023

Ready-to-eat (RTE) salads prepared from leafy vegetables sold in the streets are now common in Kano metropolis due to their convenience and acceptance by consumers. Due to the unhygienic environmental conditions and other condiments used in its preparation, vegetable salad could be contaminated with heavy metals. This study aimed to determine heavy metals safety of RTE salads hawked in Kano metropolis, Kano state, Nigeria. Forty samples of RTE salads were purposely purchase from eight local government areas of Kano metropolis and were analyzed for the presence of Cd, Cr, Hg and Pb using Atomic Absorption Spectrophotometer. The results of the analysis showed the concentration of Hg (3.208 - 1.220 mg/kg), Cr (0.756 - 0.212 mg/kg), Pb (0.392 - 0.036 mg/kg) and Cd (0.056 - 0.044). It was therefore concluded that vegetable salad sold in Kano metropolis are prone to public health concerns since the levels of Hg, Cr and Pb were found to be above the permissible limits of 0.01, 0.1 and 0.1 (for leafy vegetables) ratified by the Codex Alimentarius Commission.  Thus, prevention of heavy metals contamination in vegetables salads is necessary, this will help in prevention of acute and chronic health problems due to exposure to heavy metals from consuming street vended RTE vegetables salads in this region.
EFFECT OF PARITY ON MILK PROXIMATE AND MINERAL COMPOSITIONS AMONG THREE BREEDS OF CATTLE UNDER EXTENSIVE MANAGEMENT IN NIGERIA.
Authors: DAUDA A. , IDI Y. , JIBRIN D.N.
Published: November 2023

A total of 270 cows comprising 90 each of Sokoto Gudali, White Fulani, and Red Bororo were used for the study. Each breed was replicated into three parities of 30 cows each. 5ml of milk samples were collected from each cow. The parameters analyzed were milk protein, fat, ash, moisture, calcium, iron, phosphorus, and sodium. The data were subjected to analysis of variance and mean were separated by Duncan multiple range test. Results in Sokoto Gudali revealed that Parity 3 was significantly (p<0.05) higher in milk ash 0.43%, moisture 82.08%, Fe 1.23 mg/L and Na 75.36 mg/L. Parities 1 and 2 were not significantly (p>0.05) different in milk ash, moisture, Fe as 0.36% and 0.37%, 81.72% and 81.21% and 1.02 mg/L and 1.15 mg/L respectively, however they were significantly (p<0.05) lower than the values (0.43 %, 82.08 % and 1.23 mg/L) obtained in parity 3. In Red Bororo, Parity 1 was significantly (p<0.05) higher in milk protein 3.97% whereas parity 3 was significantly (p<0.05) low in milk protein 3.01%. Parity 1 was significantly (p<0.05) higher in Fe, P and Na as 1.01mg/L, 375.62mg/L and 71.22mg/L respectively whereas parity 2 and 3 were same and significantly (p<0.05) low in Na as 62.68mg/L and 64.62mg/L respectively. In White Fulani Parity 1 was significantly (p<0.05) higher in milk protein 4.52% whereas parity 2 was significantly (p<0.05) low in milk protein 3.93%. Parity 3 was significantly (p<0.05) higher in milk ash, moisture, Ca, Fe and Na as 0.46%, 85.25%, 611.48mg/L, 1.23mg/L and 75.33mg/L respectively. The milk parameters increased with increased in parity which might be influenced by development of animal mammary glands.
Studi Penambatan Molekuler Senyawa Tectoquinone Terhadap Enzim α-Glukosidase
Authors: Najib Ahmad , Razak Rais , Mujtahid Izzatul Fikril
Published: November 2023

The investigation focused on conducting an in silico screening of chemical compounds isolated from Syzygium oblanceolatum (C.B.Rob) to identify potential bioactive compounds that could act as inhibitors of α-Glucosidase. This screening involved tectoquinone as the potential inhibitor for α-Glucosidase and employed the Autodock Vina Docking process. The target enzyme, α-Glucosidase, was used as the receptor with 20 binding sites on the enzyme receptor 1LWJ and the Autodock Vina program was utilized for this purpose. The values of ∆Gbind and the lowest RMSD were determined for each of the 20 targeted binding sites on 1LWJ, representing the free energy change (∆G) resulting from the docking. The docking results demonstrated that the free energy change (∆G) for the 20 targeted binding sites ranged from -6.346 kcal/mol to -9.720 kcal/mol. The most favorable free energy change (∆G) was observed at the 16th binding site with a value of -9.720 kcal/mol, while the highest was recorded at the 18th binding site with a value of -6.346 kcal/mol.
Analisis dan Perancangan Sistem Informasi Akuntansi Penjualan pada CV BHT
Authors: Tjandra Fernando , Utari Widyaningdyah Agnes
Published: November 2023

Penelitian ini dilakukan pada siklus penjualan CV BHT. Perusahaan ini bergerak dalam bidang perdagangan formal pakaian pria seperti jas, kemeja dan celana dengan ukuran sesuai pesanan. Beberapa permasalahan yang terdapat pada siklus penjualan perusahaan ini adalah tidak dimilikinya sistem pengingat jatuh tempo piutang, dokumen yang digunakan belum memiliki format, dan tidak dimilikinya sistem yang dapat memberikan keterangan mengenai piutang pelanggan. Tujuan penelitian ini adalah menganalisis dan merancang sistem informasi akuntansi terkomputerisasi pada CV BHT atas siklus penjualan untuk mengatasi permasalahan yang ada. Data yang diperoleh dalam penelitian ini berasal dari pihak internal CV BHT melalui proses wawancara, observasi, dan dokumentasi.
ANALISIS PENERAPAN SISTEM INFORMASI AKUNTANSI PEMBELIAN KEPERLUAN KANTOR KEBUN/PABRIK OLEH KANTOR DIREKSI MEDAN PADA PT.PD PAYA PINANG
Authors: Zulfitri Sakinah , Hermain Hendra
Published: November 2023

Information systems are crucial for businesses; an effective system tailored to business demands can help it work better and achieve its goals and vision. The accounting information system that should be used must have periodic calculations between costs and operating results, and the financial information provided by the organization to relevant parties or management should be accurate and correct, where actions need to be implemented accurately and efficiently, reducing the risk of internal errors in generating information that will serve as a reference for future decision-making. The purpose of this research is to analyze and evaluate the implementation of the purchasing accounting information system for office needs at the Medan directorate office of PT PD Paja Pinang. The qualitative descriptive analysis method was used in this research. The qualitative descriptive analysis method includes the analysis, description, and summary of various conditions and situations from various data collected through interviews or observations of research problems that occur in the field. Research findings reveal that the implementation of the purchasing accounting information system has been carried out in accordance with existing procedures.
Strategi Pengembangan Bisnis Warung Makan Warkos di Kota Salatiga
Authors: Lois Putra Laka Marthinus , Nuswantara Bayu
Published: November 2023

Warkos di Salatiga bergerak di bidang kuliner dengan varian makanan minuman. Jenis penelitian di lakukan deskriptif kualitatif, menggunakan Teknik trianggulasi sumber. Teknik analisis data menggunakan IFE, EFE ,pencocokan data IFE dan EFE , Analisis SWOT. Hasil dari penelitian ini menunjukan faktor internal yang mengembangkan Warkos adalah menu makanan yang disajikan,ketrampilan juru masak, harga makanan dan minuman yang relatife murah skor rata-rata bernilai 2,889 pada IFE. Faktor eksternal  Warkos di Salatiga diperoleh peluang perijinan kepada RT/RW dan ancamannya pesaing usaha warung, harga bahan baku, UMR dan tingkat upah 3,278 pada matriks IFE.
Pengaruh Struktur Modal, Likuiditas Dan Ukuran Perusahaan Terhadap Profitabilitas Pada Sub Sektor Food And Beverage Di Bursa Efek Indonesia Periode 2020 - 2022
Authors: Wulandari Lidia , Widyastuti Indria
Published: November 2023

This research was conducted to examine the effect of the variables capital structure, liquidity and company size on profitability partially in food and beverage sub-sector companies listed on the Indonesia Stock Exchange for the 2020-2022 period. In addition, to test the feasibility of the variable influence regression model; capital structure, liquidity, and company size on profitability simultaneously in food and beverage sub-sector companies listed on the Indonesia Stock Exchange for the 2020-2022 period. The population in this study is 47 companies that have been and are still listed on the Indonesia Stock Exchange for the 2020-2022 period. The sampling technique used ispurposive sampling and obtained a sample of 17 companies. The data analysis technique used is to use multiple linear regression tests. The results showed that the capital structure partially affects profitability. Other variables in this study, namely liquidity partially has no significant effect on profitability, and company size partially has no effect on profitability. Simultaneously, capital structure, liquidity and company size have no effect on profitability. The predictive ability of the three variables on profitability is 9.90% as indicated by the magnitude adjusted R squre of 0.099 while the remaining 90.1% is influenced by other factors not included in the research model.
Study on growth and yield of some aromatic rice varieties
Authors: Masud TA , Roy TS , Rahman A , Mahmud MH , Hossain MD
Published: November 2023

A field experiment was conducted at Agronomy field of Sher-e-Bangla Agricultural University, Sher-e-Bangla Nagar, Dhaka during the period from June to December 2017 with seventeen aromatic rice varieties viz., V1= Chiniatap 1, V2= Chiniatap 2, V3= Kataribhog 1, V4= Kataribhog 2, V5= BRRI dhan34, V6= BRRI dhan37, V7= BRRI dhan38, V8= BR5/Dulabhog, V9= Khoisanne, V10 = Sadasanne, V11= Zirabhog, V12= Begun bichi, V13= Shakkhorkhora, V14= Chinigura, V15= Kalijira, V16= Badshabhog, V17= Modhumala to study on growth and yield of some aromatic rice varieties. The experiment was laid out in a Randomized Complete Block Design (RCBD) with three replications. Regarding growth and yield parameters, the highest number of total tillers hill−1 (23.33), leaf area index (5.38), flag leaf length (30.12 cm), number of effective tillers hill−1 (21.67), panicle length (32.00 cm), number of grains panicle−1 (230.3), number of filled grains panicle−1 (212.7), grain yield (3.42 t ha−1), straw yield (6.19 t ha−1) and number of biological yield (9.610 t ha−1) were found in var. BRRI dhan37 but the highest 1000- grains weight (22.80 g) and harvest index (37.48%) were found Modhumala followed by  BRRI dhan34, respectively. The lowest number of effective tillers hill−1 (13.33), panicle length (24.67 cm), grain yield (1.583 t ha−1), straw yield (4.083 t ha−1), biological yield (5.667 t ha−1) and harvest index (27.89%) were found in the var. Modhumala.

Bangladesh Agron. J. 2023, 26(1): 1-8
Escalation of Growth and Yield in Mungbean by Sink Manipulation: An Approach for Minimizing Pod Picking Episode
Authors: Talukder AHMMR , Ahmed F , Ahmed IM , Mahfuza SN , Ahsan AFMS , Mokarraoma N , Shahadat MK , Nahar L
Published: November 2023

Farmers’ frequently experience difficulties with their mungbean (indeterminate type) crops harvests due to continuous picking that prolong the pod-picking episode and cause an economic crisis. To solve these issues, deflowering strategies (sink manipulation) were employed in this study following the randomized complete block design. A series of deflowering strategies were started from 40 days after sowing (DAS) to 55 DAS; resulting reduced pod production as well as pod picking episode (3 to 4 times) with 6.8-36.8% seed yield compared to control. The minimum seed yield reduction was 6.8%; deflowering at 55 DAS; with the maximum gross margin Tk.112,800 ha−1. Considering relative yield, yield reduction, and gross margin, 50 or 55 days produced flower (which would be matured within 60-65 DAS) could be considered for obtaining the economic seed yield.

Bangladesh Agron. J. 2023, 26(1): 48-55
Efficacy of Herbicide Mixtures for Transplanted Aman Rice in Silty Clay Loam Soil of Bangladesh
Authors: Jame Zobayra Haque , Zahan Taslima , Hossain HMM Tariq , Roy Promita Shikha , Masum Sheikh Muhammad
Published: November 2023

Weed management plays an important role in obtaining target yield. A field experiment was carried out at the Agronomy field of Sher-e-Bangla Agricultural University, Dhaka, Bangladesh, from July to December 2019 to get the most effective weed control strategy for transplanted Aman rice. The soil of the study field was silty clay loam in nature. The study consisted of two factors i.e., variety (4: Chinigura, BR11(Mukta), BRRI dhan56, and BRRI hybrid dhan6) and herbicide (4) viz., Bispyribac-sodium WP @ 150 g ha-1, Acetochlor 14% + Bensulfuron methyl 4% WP @ 750 g ha-1, Pretilachlor 6% + pyrazosulfuron 0.15% WP @ 9.88 kg ha-1, and weedy check as a control. The experiment was laid out in a split-plot design with three replications. Thirteen weed species were found in the experimental plots, mostly broadleaf and sedge. Monochoria vaginalis was the most dominant weed species. The study noticed that the application of mixed herbicides offered better weed control over single herbicide application. Application of Acetochlor 14% + Bensulfuron methyl 4% WP @ 750 g ha-1 significantly reduced weed density and biomass and was the best way of controlling complex weed flora. The study marked out BR11 (Mukta) as the most potential aman rice variety to produce the highest yields at applying Acetochlor 14% + Bensulfuron methyl 4% WP @ 750 g ha-1. This treatment gave the highest gross return (Tk. 1,46,010), net return (Tk. 88,699), and benefit-cost ratio (2.55). Therefore, the study suggests the application of mixed herbicides and BR11 (Mukta) to get the optimum yield of transplanted Aman rice and maximum economic benefit.

Bangladesh Agron. J. 2023, 26(1): 56-74
Interrelationship between food intake & nutritional anaemia among the children studied in a tertiary care hospital in Dhaka city
Authors: Hossain Md Delwar , Mowlah Golam , Razzak Monira
Published: November 2023

This study was carried out on 128 children of which 80 were male & 48 were female admitted in Paediatric department of DMCH. They were 1 to 12 yrs. 31, 27, 24 and 46 children were of 1-3 yrs, 4-6 yrs, 7-9 yrs & 10-12 yrs age group respectively. A cross sectional sample survey study was carried out. Main variables were age, family size, monthly family income, parents education & occupation Hb and PCV levels.58% children were illiterate group which also includes less than 5 yrs children. 12% were at primary level & 30% were at high school level. The children of 1-3yrs, 4-6yrs, 7- 9yrs & 10-12yrs age groups took an average of 290, 285, 505 & 555 gm foods/child/day. Cereals intake was highest (67.7%) in comparison to other foods. Consumption of meat, fruits, fats & milk was very low. Iron intake was found more than requirement & Vit-C intake was found lowest of the nutrients requirement.

The study revealed the children met protein, iron, folic acid, Vit-A, Vit-B12, Vit-C, Vit-B2 , Vit-B6 , Zinc & Copper 70.79%, 122.2%, 92%, 72%, 68.5%, 55%, 83%, 57%, 89% & 82% respectively of the requirements. Less than 50% of the requirements of iron, protein, Vit-A, Vit-C, Vit- B2 & folic acid is met by 15%, 50.5%, 39%, 45%, 12% & 29% children respectively.

Mean Hb level is found (10.39±2.23)gm/dl of blood & ranges from 4.7gm/dl to 12.9gm/dl & mean PCV level is found (30.1±2.21) percent & ranges from 13.63% to 37.41%. According to Nutrition Survey of Rural Bangladesh 1981- 82 & WHO, 1972 28,29 Hb leve <11gm/dl for <6yrs and < 12gm/dl for 6-12 yrs age group are considered to be anaemic. In the present study I found 20(15.62%) children were severely anaemic, 32(25.26%) children were moderately anaemic & 17 (13.02%) children were mildly anaemic by this criterion.

Peripheral blood film showed 5.47% & 26.57% children with normocytic & microcytic hypocromic anaemic respectively & 14.85% children with malignancy of blood(ALL). Haemolytic anaemia with raised serum bilirubin level was found in 6.25% children. Eosinophilia was found in 18% children. Aplastic anaemia was found in 5.47% children . Aplastic anaemia & malignancy of blood were confirmed by bone marrow examination.

Journal of Paediatric Surgeons of Bangladesh (2016) Vol. 7 (2): 29-34
Renal primitive neuroectodermal tumor (RPNET) in children
Authors: Islam K M  Didarul , Munmun Umme Habiba Dilshad , Alam Shoheli , Mahammad Noor , Amin Md Ruhul , Sah Sanjay Kumar , Silwal Shirish
Published: November 2023

Renal primitive neuroectodermal tumor (rPNET) as a member of Ewing’s sarcoma family is extremely rare and usually occurs in children and young adults. Most literature about rPNET was isolated case reports. Here we described a case of renal PNET in a 7-year-old girl who presented at our Paediatric Surgery Department of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh with fever, left flank pain and mass Ultrasonogram (USG) and Computer tomography (CT) scan revealed a huge mass in the left kidney. The patient underwent left radical nephrectomy with neoadjuvent chemotherapy on April,2016. Histopathology and immunohistochemistry (IHC) confirmed the diagnosis of PNET. She did not receive adjuvant chemotherapy, as advised. She had a local tumor recurrence 3 months after the surgery and continued to deteriorate but not developed distant metastasis. She again received 2-cycle of chemotherapy but size did not decrease. So re-do surgery was performed on 10.01.2017 and send to paediatric haemato-oncology department of BSMMU for further management. rPNET is rare and presents aggressive clinical behavior and worse prognosis. We expect that further awareness and study of this rare tumor can be had by presenting our case.

Journal of Paediatric Surgeons of Bangladesh (2016) Vol. 7 (2): 66-71
Destinos
Authors:   Universidad del Azuay, Vanégas-Coveña Sara
Published: November 2023

La poesía es el destino privilegiado del lenguaje dice Gastón Bachelard. Hay poemas, que por sus logros estéticos encuentran otros destinos, en otros idiomas. Esta edición celebra las travesías de la lengua y la poes´ía reuniendo cerca de 50 poemas de Sara Vanégas, vertidos por múltiples traductores a varios idiomas (inglés, francés, italiano, alemán, rumano, portugués, Kichwa), e incluso al mismo español, pues la autora escribió algunos poemas en alemán. Además de su valor multilingue, esta edición constituye, sin duda, una de las mejores antologías de Sara, pues no solo es el fruto de la elección personal de la autora, sino del escogimiento de esos lectores altamente calificados que son los traductores. "Mi casa es un enjambre de alas que se fueron" dice una línea de Sara que aparece en estas páginas. Esta certeza vital, enunciada poéticamente, opera aquí un giro adicional: pues si las alas del deseo y la imaginación alzaron vuelo y partieron, en este libro vuelven transformadas, aleteando con la música propia de las lenguas extranjeras.
RELATO DE EXPERIÊNCIAS EXTENSIONISTAS POR MEIO DO PAEC: PRÁTICAS SOCIOEDUCATIVAS E SENSIBILIZAÇÃO
Authors: Silva Ogoshi Rosana Claudio , Silva Ogoshi Rosana Claudio , Rachinski D'Agostini Rosana , IZAEL CARDOSO Paulo , POMPERMAIER SIMONE , Lavinha Amanda
Published: November 2023

O relato de experiências extensionistas vivenciados por meio do Programa de Apoio a Extensão e Cultura da UNIARP é uma prática desenvolvida desde primeiro semestre letivo de 2002 por meio de projetos de extensão propostos por acadêmicos e professores extensionistas dos cursos de graduação com vistas a promover a indissiossibilidade do ensino, da pesquisa e da extensão a partir de diálogos em rede. Para tanto, os projetos de extensão visam a, em suas atividades e ações socioeducativas, proporcionar experiências ao acadêmico no âmbito socioambiental, socioeconômico e sociocultural numa perpectiva de impactar positivamente em suas experiências com a comunidade através de vivências, experiências e conhecimentos voltados à novas práticas e de inovação social. À vista de iniciativas assim, espera-se obter possíveis resultados ou novos conhecimentos sobre sua futura formação e, em seguida, a perspectiva de impactar positivamente em melhorias para a comunidade. Contudo o relato apresenta as iniciativas desenvolvidas pelos projetos destaques do PAEC no período de 2021 e 2022, nos eixos temáticos de extensão, principalmente de cidadania, saúde e educação, demonstrando uma melhoria na integração dos acadêmicos com o público alvo, possibilitando despertar o conhecimento sobre a importância acerca das práticas extensionistas na formação humana e ética do profissional.
The Perception of school authorities and teachers in inculcating Islamic values in the National Educational System
Authors: Mardiani Ade , Ismail Halim Bin , Ahmad Ismail Sheikh
Published: November 2023

Tujuan dari penelitian ini adalah untuk mengidentifikasi persepsi penanaman Nilai-nilai Islam dalam Sistem Pendidikan Nasional (Sistem Pendidikan Nasional Bernafaskan Islam) di kalangan otoritas sekolah dan guru di Sekolah Menengah Swasta di Lampung Indonesia. Penelitian kualitatif diadaptasi sebagai metode dalam penelitian ini. Pendekatan fenomenologi telah dipilih dalam upaya mencapai tujuan penelitian. Formulir wawancara semi terstruktur, formulir observasi, dan analisis dokumen digunakan sebagai alat pengumpulan data. Wawancara semi terstruktur diperoleh dengan mewawancarai tiga otoritas sekolah dan tiga guru. Data wawancara ditranskrip. Selanjutnya, data dianalisis secara manual untuk menghasilkan tema. Tema-tema tersebut telah diperiksa oleh dua orang penilai yang ahli di bidangnya. Temuan penelitian ini mengungkapkan bahwa penanaman nilai-nilai Islam dalam Sistem Pendidikan Nasional telah dilakukan selama tiga puluh tahun melalui pembiasaan shalat berjamaah, membaca Al-Qur'an dan Asmaul Husna sebelum belajar, budaya salam, dan program Tahfidzul Qur'an. Mencermati hasil penelitian tersebut, pihak sekolah dan guru hendaknya mengevaluasi secara berkala terkait penanaman nilai-nilai Islam karena perkembangan globalisasi yang dirasakan kuat dan terbuka saat ini.Kata Kunci; Persepsi, Penanaman nilai-nilai Islam, Sistem Pendidikan Nasional AbstractThe purpose of this research was to identify the perception of the inculcation of Islamic Values in the National Educational System among the school authorities and the teachers at a Private Secondary School in Lampung Indonesia. Qualitative research was adapted as the method in this study. The phenomenology approach has been chosen in the quest of arriving at the objectives of the study. A semi-structured interview form, observation form, and document analysis were used as data collection tools. Semi-structured interview acquired by interviewing three school authorities and three teachers. The data of the interviews were transcribed. Subsequently, the data was analyzed manually to generate the themes. The themes have been checked by two raters who are experts in the field. The finding of this study revealed that the inculcation of Islamic values in the National Educational System has been conducted for thirty years through the habituation of prayer in congregation, reciting Qur'an and Asmaul Husna before learning, the culture of greetings, and the program of Tahfidzul Qur'an. Considering the research findings, the school authorities and teachers should evaluate regularly pertaining to the inculcation of Islamic values because of the development of globalization that felt strong and open currently.Keywords; Perception, Inculcating Islamic values, National Educational System
Pure fruit juice and chronic diseases
Authors:   , Scheffers Floor Rinske
Published: November 2023

Pure fruit juice (without added sugars or other additives) has similarities with both whole fruit and sugar-sweetened beverages. Like whole fruit, pure fruit juice contains vitamin C and flavonoids, but has the low satiety and similar sugar content as sugar-sweetened beverages. While dietary guidelines worldwide consistently promote fruit consumption and discourage drinking sugar-sweetened beverages, dietary guidelines on drinking pure fruit juice differ between countries. This thesis aimed to answer whether drinking pure fruit juice could be a (partial) substitute for eating whole fruit or if it should be discouraged like sugar-sweetened beverages. For this research, data of two cohort studies was used, the Dutch contribution to the European Prospective Investigation into Cancer and Nutrition (EPIC-NL) cohort and the Dutch Prevention and Incidence of Asthma and Mite Allergy (PIAMA) birth cohort study. Moderate consumption of pure fruit juice was associated with a lower risk of cardiovascular diseases. Pure fruit juice was not associated with type 2 diabetes or asthma. The current body of evidence is still limited. Therefore, it is not advisable to substitute pure fruit juice for whole fruit, mainly because of the low satiety in combination with the high sugar content. Nevertheless, there is no need to discourage pure fruit juice consumption in the same way as sugar-sweetened beverages in dietary guidelines. Moderate consumption of pure fruit juice can be a part of a healthy diet.
Nanobodies targeting complement
Authors:   , Struijf Eva Madelon
Published: November 2023

The complement system is an important part of the human immune system that fights invading pathogens and removes apoptotic host cells, tumor cells and immune complexes. It consists of roughly 30 proteins that circulate in the blood and other body fluids and its activity is driven by proteolytic cascades and conformational changes. The role of the complement system in health and disease is extensively being studied. Although huge progress is made in the last decades, there are still major fundamental and clinical questions that yet remained unanswered. Novel tools and therapeutics that can inhibit, and/or discriminate complement precursor proteins from activation proteins are therefore still needed. We aimed to develop llama-derived nanobodies directed towards different complement components. In this thesis, we focused on central complement component C5 and activation products C3b and C5b6. To obtain complement targeting nanobodies, we immunized two llamas, created nanobody phage display libraries, and performed multiple rounds of phage display panning. For all complement proteins used during immunizations, we successfully identified multiple nanobodies. In the end, we prioritized four nanobodies for further characterization because of their potent binding and inhibitory activity or their unique capacity to discriminate activated complement products from their precursors. Briefly, UNbC3b-1 targeting C3b (chapter 2) specifically binds complement activation product C3b and not precursor C3 and efficiently inhibits alternative pathway convertase functioning. UNbC5-1 and UNbC5-2 (chapter 3) are two potent C5 inhibiting nanobodies that bind C5 on distinct sites. Using cryo-EM we identified the exact binding sites of UNbC5-1 and UNbC5-2 and showed that they overlap with the binding sites of known complement inhibitors eculizumab and RaCI3, respectively. Furthermore, we show that UNbC5-1 can also bind and inhibit a genetic variant of C5, called C5 R885H, which cannot be bound and inhibited by eculizumab. UNbC5b6-1 (chapter 4) is a nanobody that specifically binds to the complement activation complex C5b6, but not to precursor proteins C5 and C6. This nanobody does not interfere with complement activity. All in all, the here identified nanobodies can serve as tools to gain a better understanding of the molecular mechanisms of complement activation and hold promise for further development as diagnostic tools and therapeutics.
Coherent analysis in electroencephalography. Experience in the use of coherent analysis in the assessment of disorders of human mental functions in practical electroencephalography. (Lecture three)
Authors: Ivanov L. B. , Budkevich A. V.
Published: November 2023

It is discussed what actually useful coherent analysis can give in solving the problem of assessing the system- functional organization of cortical rhythms, which underlies the clinical interpretation of quantitative indicators of intracerebral connections. The authors emphasized. That in the basis of the assessment of disorders of the mental function of the brain according to EEG data, one should look for signs of dissociation of the level of wakefulness in non-sleeping people. It is necessary to look for features of the electroencephalographic picture, which can be considered as neurophysiological neurotic patterns and, most importantly, an assessment of the state of the systemic- functional organization of the cortical rhythm, interpreted as a state of hypofrontality. The authors took the path of visual illustration using examples of specific patients with various pathological states of brain function. The features of changes in coherence indices in patients with hyperactivity syndrome, in violation of the function of attention, with mental retardation, in vegetative- vascular dystonia are given. The authors cite the observation of a child with sensorineural hearing loss from birth and connect the fact of a decrease in the level of intertemporal relations, not with the underlying disease, but with the lack of oral speech skills. The paper emphasizes that hypersynchronization of the alpha rhythm is quite pathognomonic to the state of increased anxiety. The authors explain in detail under what states of mental dysfunction the values of the average coherence are more informative, and in which the values of the dominant frequency. In conclusion, the authors complain about the unsatisfactory software capabilities of mathematical processing in some EEG computer systems, so neurophysiologists have unequal opportunities.
Systolic function of the left and right ventricles and myocardial strain in young adults with metabolic syndrome
Authors: Bartosh-Zelenaya S. Y. , Stepanova V. V. , Pavlova N. E. , Mamaeva O. P. , Sherbak S. G.
Published: November 2023

The purpose of this article is to evaluate the systolic function of the left and right ventricles and measure myocardial Strain in young people (from 18 to 44 years old) with a newly established clinical and laboratory diagnosis of metabolic syndrome (MS) according to the criteria of the International Diabetes Federation (IDF), to identify possible early markers of myocardial dysfunction. All patients underwent standard transthoracic echocardiography (EchoCG) with assessment of systolic function of the left and right ventricles (LV and RV). The work detects early markers of ventricular myocardial dysfunction using speckle tracking 2D and 4D EchoCG, and also investigates the relationship between the main components of MS and echocardiographic parameters. With the help of a comparative analysis, statistical data were revealed on the low global longitudinal strain of the left and right ventricle in 2D and 4D in the main group compared with the control group. In individuals with MS, the mean values of global circular strain (GCS), radial (GRS) strain and global area strain (GAS) of the left ventricle were also significantly lower than the control group. Indicators obesity diseases (body weight and waist circumference) had a negative correlation with the ejection fraction (EF) and parameters of ventricular strain.
Osteoporosis and body composition in old patients with amputated lower limbs
Authors: Topolyanskaya S. V. , Bubman L. I. , Koshurnikov D. S. , Karpov V. V. , Nechaev A. I. , Khan S. O. , Lytkina K. A. , Melkonyan G. G. , Dvoretskyi L. I. , Ratchina S. A.
Published: November 2023

The study aim was to investigate bone mineral density (BMD) and body composition in old patients with amputated lower limbs.

Materials and methods. This work is a cross-sectional study, which enrolled 31 patients, who underwent amputation of one of the lower extremities. The mean age of the study patients was 73.4±9.0 years, ranging from 60 to 101 years. The majority of study patients were men (77.4%). 41.4% of patients underwent amputation of the left lower limb, 58.6% – right. The time from amputation to enrollment in the study ranged from 4 to 444 months, with a median of 30 months. Bone mineral density in the lumbar spine and proximal femurs was analyzed by dual energy x-ray absorptiometry.

Results. Osteoporosis in the proximal part of the left femur was registered in 51.7% of patients, osteopenia – in 17.2%, normal BMD – in 31.1% of cases. Osteoporosis in the proximal part of the right femur was observed in 64.0% of patients. In the lumbar spine, osteoporosis was found only in 6.9% of patients. The mean T-score in the lumbar spine reached +0.38 SD, in the proximal left femur – -1.5 SD, in the left femur neck – -2.1 SD, in the proximal right femur – -2.0 SD, in the right femur neck – -2.1 SD. In the case of amputation of the left lower limb, the left femur BMD averaged 710.8±239 mg/cm3, the left femur T-score – -2.6±1.6SD, the T-score in the left femur neck – –3.0±1.3 SD, with the intact left leg – 980.1±194 mg/cm3,–0.8±1.5SD,–1.5±1.2SD, respectively (p=0.002, p=0.005 and p=0.006). In case of amputation of the right lower limb, the right femur BMD reached 743.8±268 mg/cm3, right femur T-score – -2.4±1.7SD, the T-score in the right femur neck – -2.4±1.7SD, with the intact right leg – 909.9±211.0 mg/cm3, -1.2±1.5SD, -1.5±1.5SD, respectively (p=0.09, p=0.06 and p=0.1). The likelihood of developing osteoporosis in the left femur with amputation of the left leg increased by 9.8 times, compared with patients who had a preserved left lower limb (odds ratio=9.8; 95% CI=1.1–93.5; p=0.02). In patients with amputation of the left leg, inverse correlation was registered between bone mineral density and the time from the moment of amputation to inclusion in the study (r= -0.65, p=0.03).

Conclusion. Preliminary results of this study demonstrate a decrease in bone mineral density in the proximal femur of the amputated limb. Further studies are needed to study BMD in amputees and to elucidate the pathogenetic basis of the relationship between BMD and other clinical and laboratory parameters in this group of patients.
Psychocognitive dysfunction in comorbid patients in the post-COVID period
Authors: Khidirova L. D. , Starichkova A. A. , Lukinov V. L.
Published: November 2023

Introduction. Currently, psychopathological symptoms are noted in a third of patients with COVID-19, according to published systematic reviews. Aim. To study psychocognitive function in comorbid patients depending on the coronavirus infection caused by SARS-CoV-2.

Material and methods. The observational analytical cohort study included 223 patients with AF and comorbidity (ischemic heart disease, arterial hypertension, obesity, type 2 diabetes mellitus) aged 60–74 years, who were divided into 2 groups: 1st –  123 patients without COVID –19 and 2nd – 110 patients with a history of COVID-19 and the presence of PCS. The group of patients with a history of COVID-19 was retrospectively divided into 2 groups depending on the intake of sulodexide; patients in the subgroups were comparable. The work assessed psychological disorders (anxiety and depression) and cognitive status using specialized scales «HADS» and «SPMSQ».

Results. In patients with COVID-19, compared with patients from group 1, there is a more pronounced depressive syndrome (p<0.001); subclinical depression in 26% of patients (p<0.001) and the absence of the latter in group 1; clinically pronounced depression was found in 15% (p=0.007). At the same time, the severity of subclinical symptoms of anxiety syndrome was noted in patients without COVID-19, and clinically signiﬁcant anxiety was more often observed in recovered patients, although statistical signiﬁcance was not achieved. When assessing cognitive function, it was found that moderate dysfunction was observed in patients with COVID-19 signiﬁcantly more often (p=0.001). In the sulodexide group, only mild cognitive dysfunction was detected (14%), and the majority of patients taking sulodexide had no cognitive dysfunction.

Conclusion. Thus, in comorbid elderly patients in the post-COVID period, an increase in the number of people with psychocognitive disorders was noted. In this regard, long-term follow-up of patients who have undergone COVID-19 is necessary, both for the dynamic assessment of underlying diseases and the analysis of psychocognitive status. In addition, it should be noted that the drug sulodexide, consisting of a heparin-like fraction and dermatan sulfate, has many pharmacodynamic (anti-inﬂammatory, angioprotective, anticoagulant, antiﬁbrotic) and pharmacokinetic advantages (safety, the possibility of oral administration) can effectively prevent the development of cognitive dysfunction, which requires even further in-depth research.
Güvenlik Kültürü: Son On Yıldaki (2013-2023) Yayınların Bibliyometrik Analizi
Authors: ELMACI Deniz , KUN Sermin , KOÇAK Çağrı Ceylan
Published: November 2023

Literatürde gelişmiş bir güvenlik kültürü, çalışanların işyerlerinde sağlıklı ve güvenli şartlarda çalışabilmeleri için işveren, çalışan ve yöneticilerin tehlike ve riskleri önceden algılama, önlem alma ve kontrol etmeye yönelik tutum ve davranışlara sahip olmaları olarak tanımlanır . İşyerinin güvenlik kültürü çalışanların güvenlik algısının göstergesidir. Bu konu ile ilgili yapılan çalışmaların artması güvenlik kültürünün geliştirilmesine hizmet edecektir. Bu düşünce ile son on yılda konu ile ilgili yapılan çalışmalar bibliyometrik yöntem ile VOSviewer aracılığıyla analiz edilmiştir. Bibliyometrik analiz, araştırmaların eğilimini analiz etmek, ortaya çıkan bilim alanlarını belirlemek, makalelerin hangi dergilerde ve ne sıklıkla yayınlandığını belirlemek için kullanılmaktadır. Hazırlanan çalışmada, Web of Science™(WoS) veri tabanında 2013 ve 2023 yılları arasında yayımlanan 4041 çalışma incelenerek, güvenlik kültürü konusunda bir bibliyometrik analiz oluşturulması amaçlanmıştır. Araştırmada, 123 farklı ülkeden 13432 yazara ait 1397 farklı dergideki bilimsel çalışmalar değerlendirilmiştir. Güvenlik kültürü çalışmalarının temel olarak (1) organizasyonel (örgütsel) güvenlik kültürü ve (2) hasta güvenliği kültürü şeklinde iki büyük kümeye ayrıldığı, multidisipliner ve çok yönlü bir kavram olduğu sayılarla ortaya konulmuştur.
RANCANG BANGUN SISTEM INFORMASI PENERIMAAN KAS LAYANAN TINDAKAN MEDIS PUSKESMAS BOTANIA BATAM KOTA
Authors: Elisa Erlin , Tukino Tukino , Amrizal Amrizal
Published: November 2023

Public health centers play a crucial role as frontline healthcare service providers, dedicated to enhancing the well-being of their communities. Ensuring the delivery of the best possible services is a primary responsibility. However, one significant challenge they face is the manual recording of general medical services, making the process susceptible to transaction recording errors. This study's objective is to develop an analysis and design for a cash receipt application tailored to medical action services, addressing this issue. To achieve this goal, the research employs various methods, including data collection through interviews and documentation techniques. The current system is thoroughly analyzed, identifying its shortcomings and areas for improvement. Additionally, the Unified Modeling Language (UML) is employed to create a comprehensive design for the proposed cash receipt application. The outcome of this study is a well-crafted design for a medical action service cash receipt application. This application has the potential to streamline the process, reduce errors, and enhance the overall efficiency of health center operations. Implementing this system could significantly contribute to the improvement of healthcare services in the community, ultimately benefitting the public's health and well-being.
Comment on Islam et al. Helminth Parasites among Rodents in the Middle East Countries: A Systematic Review and Meta-Analysis. Animals 2020, 10, 2342
Authors: Hamzavi Yazdan , Bozorgomid Arezoo , Rostamian Mosayeb
Published: November 2023

I read with great interest the article by Islam et al. entitled “Helminth parasites among rodents in the Middle East countries: a systematic review and meta-analysis” published in Animals in December 2020 [...]
Determining the Effect of Pancreatic-like Enzymes (PLEMs) Added to the Feed of Pregnant Sows on Fetal Size of Piglets to Minimize IUGR Syndrome Caused by Fetal Malnutrition
Authors: Pieszka Marek , Szczurek Paulina , Orczewska-Dudek Sylwia , Kamyczek Marian , Pieszka Magdalena
Published: November 2023

The present study aimed to develop a feeding strategy for pregnant sows that involved the prenatal administration of a mixture of pancreatic-like fungal enzymes, such as lipase, amylase, and protease, at (1) 1–115 days of gestation (group D1) and (2) 80–115 days of gestation (group D2) and to carry out a comparison with groups of sows that were not receiving such supplementation (negative control (NC) and positive control (PC)). It was found that the administration of the enzyme supplement resulted in a significant shortening of gestation (p ≤ 0.01). The pancreatic enzymes administered to sows had a significant effect on the number of liveborn piglets and weaned piglets, which was higher compared with the control groups that did not receive supplementation: D1—12.1 ± 1.1 and 11.12 ± 1.1 and D2—12.8 ± 1.3 and 11.75 ± 0.07 vs. the control groups KN—10.7 ± 1.0 and 9.62 ± 0.95 and KP—10.9 ± 1.2 and 10.15 ± 1.0 (p < 0.006), respectively. Significant changes in piglet growth were observed after weaning up to 70 days of age. During this period, the most favorable growth parameters were observed in groups D2 (420 ± 91 g) and PC (407 ± 103 g), in which piglets obtained a mixture of pancreatic enzymes (lipase, amylase, and protease) at 3 weeks of age, and significantly higher weight gain and feed intake were observed compared with groups NC (378 ± 114 g) and D1 (381 ± 96 g) (p ≤ 0.007). In contrast, insulin levels were significantly lower in groups D1 and D2, with values of 6.8 IU/mL and 6.7 IU/mL, respectively, compared with groups NC (14.6 IU/mL) and PC (16.6 IU/mL) (p ≤ 0.01). Piglets in group D2 had a significantly better feed conversion ratio (FCR) of 1.604 ± 0.10 compared with the other dietary groups: KN—1.986 ± 0.14; KP—1.704 ± 0.11; and D1—1.932 ± 0.15 (p ≤ 0.03). Histological imaging confirmed a significantly thicker intestinal epithelium and intestinal mesenteron in animals from groups D2 and PC (p ≤ 0.03). Animals from the groups KP, D1, and D2 receiving enzymes showed a highly significant increase in the surface area of pancreatic follicles and pancreatic surface area compared with the group without KN supplementation (p < 0.01). Furthermore, significantly higher activity of the brush border enzyme lactase was observed in groups D1, D2, and PC, with values of 32.90 ± 3.99, 30.00 ± 6.83, and 29.60 ± 29.60, respectively, compared with group NC, with a value of 21.80 ± 3.27 (p ≤ 0.01).
Mitigation of Shape Evolution and Supercapacitive Performance of CuCo2S4 Electrodes Prepared via a Simple Solvent Variation Approach
Authors: Mane Sagar M. , Wagh Komal S. , Teli Aviraj M. , Beknalkar Sonali A. , Shin Jae Cheol , Lee Jaewoong
Published: November 2023

This work demonstrates the evolution of different architectures of Cu-Co bimetallic sulfide on Ni-foam. A simple solvent-changing strategy has been adopted to develop these architectures through a solvothermal approach. When water and ethylene glycol was used as a solvent, the surface of Ni-foam seemed to be covered with a snowflake-like architecture. On the addition of glycerol instead of ethylene glycol, the growth of spongy rectangular prisms from mud-like bricks was initiated. Analyzing electrochemically, both electrodes deliver excellent capacitance. The electrode developed with water and glycerol was found to be richer in terms of capacitive performance, which gives 1459.7 F/gm (5692.8 mF/cm2) at a higher current density of 5 mA/cm2. An over-33% increment in capacitance was noted when compared with the specific capacitance (areal capacitance) of another electrode which can provide 986.6 F/gm (3157 mF/cm2) at the same current density. Both electrodes are richer in terms of providing higher rate capability above 75%, even if the current density is increased by three times. Furthermore, both electrodes deliver long-lasting storage capability, with above 80% capacitance retention over 10,000 charge–discharge cycles even at a higher current density of 60 mA/cm2. This simple solvent-changing approach can be useful for developing electrode materials with outstanding capacitive performance.