bluuebunny/crossref_metadata_2025 huggingface dataset:
Use of upadacitinib in a child with refractory ulcerative colitis
Authors: Potapov A. S. , Pushkareva A. E. , Vinokurova A. V. , Prokhorenkova M. O. , Krasnovidova A. E.
Published: September 2024

Upadacitinib a selective Janus kinase inhibitor that belongs to the group of targeted immunosuppressors or selective immu-nosuppressants, has emerged as a new strategy for immune-mediated diseases. Previously, clinical cases and studies on adult patients with inflammatory bowel disease were mostly found in the literature; in paediatric practice, this experience is very limited. Use in children is still off-label due to the lack of randomized trials. In the presented clinical case, this drug was prescribed to a 15-year-old boy for a refractory course of ulcerative colitis that had previously lost response to anti-TNF, therapy with vedolizumab and tofacitinib was also failed. Given the unsuccessful previous treatment experience, a child with refractory ulcerative colitis was prescribed upadacitinib. The drug was prescribed at a dose of 45 mg once a day for 8 weeks, then it was suggested to switch to a maintenance dose of 15 mg once a day. Without systemic glucocorticosteroid use, the patient's complaints, clinical, laboratory, and endoscopic changes persisted, but on upadacitinib therapy the boy was able to discontinue glucocorticosteroid. This example illustrates the positive dynamics according to clinical, laboratory and endoscopic data on the background of selective inhibitor of Janus kinases. A growing number of clinical cases using Janus kinase inhibitors show the need for clinical trials in a pediatric group of patients with refractory inflammatory bowel disease.
Metabolic therapy in the treatment of cardiovascular diseases
Authors: Kopylova V. S. , Boronovskiy S. E. , Sokolova L. P. , Mashkovtseva E. V. , Nartsissov Ya. R.
Published: September 2024

Today, cardio- and cerebrovascular diseases pose a severe threat to human health and life quality, leading to reduced working capacity, disability and, often, death. The most common cardiovascular diseases are arterial hypertension, chronic cerebral ischemia and ischemic heart disease. Metabolic disorders that cause oxidative stress growth, vessel wall damage, and injury of body cells and tissues, as well as affect energy formation processes are the key aspects of their formation. Glutathione is a powerful antioxidant that protects cell structures from damage by free radicals, helping to reduce oxidative stress. Eltacin has a corrective effect on these pathological processes, rising the antioxidant protection of the body by increasing the efficiency of glutathione-dependent mechanisms of cell redox regulation. As a result of the complex impact on metabolic processes in the tissue, Eltacin has not only antioxidant, but also neuro- and cytoprotective and vegetotropic effects. The drug has a positive effect on the hemodynamic performance of patients with cardiovascular diseases, which is expressed in blood flow normalization in the heart as well as in the brain. The inclusion of Eltacin in traditional therapy for cardiovascular diseases patients leads to an increase in the antianginal and hypotensive effects. Its use in combined treatment regimens contributes to structural and functional state improvement of the myocardium of the left ventricle, which is a key factor for maintaining normal heart functioning. Increased physical activity tolerance allows patients to lead a more active lifestyle, which has a beneficial effect on their overall condition and life quality. In addition, the vegetotropic effectiveness of Eltacin has been proven. It results in meteoprotective effect, which reduces weather factors influence on the hemodynamics of weather-dependent patients with arterial hypertension and ischemic heart disease. Thus, Eltacin not only improves the condition of patients and increases traditional therapy effectiveness, but also provides additional protection from adverse environmental influence.
Comorbidity of respiratory diseases and periodontal diseases
Authors: Trukhan D. I. , Sulimov A. F. , Trukhan L. Yu.
Published: September 2024

At the beginning of the 21st century, the concept of “periodontal medicine” was formed, within the framework of which the bidirectional connection of periodontal pathology with systemic diseases of the body is considered. There are two hypotheses regarding the possibility of chronic periodontal infection to contribute to the development of systemic inflammation: 1) changes in the microbiocenosis of the oral cavity and periodontal inflammation lead to an increase in bacterial translocation into the systemic bloodstream, causing the circulation of inflammatory mediators and immune complexes to other organs and systems of the body; 2) changes in the microbiocenosis of the oral cavity can lead to disturbances and changes in the intestinal microbiome due to oral intake of periodontopathic organisms. The relationship between periodontal diseases and respiratory diseases has been less studied. We searched the Pubmed and Scopus databases for articles published up to January 31, 2024, that addressed this relationship. The proximity and continuity of the oral cavity and respiratory tract allows the oral microbiome to be a major determinant of the pulmonary microbiome. It is possible to distinguish 2 main ways of translocation of periodontal bacteria into the lungs - aerogenic and aspiration. The data presented in the review suggest a probable bidirectional relationship between periodontal diseases and hospital-acquired pneumonia, the new coronavirus infection COVID-19, and COPD. The relationship between periodontal pathology and BA can be considered possible, but in a number of studies this relationship has not been confirmed, which requires further study. The connection between periodontal diseases and community-acquired pneumonia has practically not been studied, but it is possible, taking into account the direct interaction of the oral microbiota and the microbiota along the mouth-lung axis, and indirectly along the mouth-intestinal-lung axis. Non-surgical periodontal treatment is likely effective in the treatment and prevention of respiratory diseases. The data presented in the review indicate the importance of periodontal health and the need for the prevention and treatment of periodontitis pathology in pulmonary patients.
Structural changes in the cornea and tear film in keratoconus associated with dry eye syndrome on the background of the use of optical correction and tear replacement therapy
Authors: Surnina Z. V. , Averich V. V.
Published: September 2024

Introduction. The literature data confirm a relationship between keratoconus (KC) and signs of dry eye syndrome (DES). The scleral rigid gas permeable contact lenses widely used in the optical correction of keratoconus are more often used in the treatment of dry eye syndrome to protect the cornea and tear film.

Aim. To evaluate changes in the condition of the cornea and tear film in keratoconus associated with dry eye syndrome during the use of scleral rigid gas permeable contact lenses in combination with/without tear replacement therapy.

Materials and methods. A total of 30 patients (60 eyes) with bilateral stabilized non-operated keratoconus at different stages associated with dry eye syndrome were examined. The patients were divided into groups: Group 1 included 15 patients (30 eyes), who used 0.9% sodium chloride (saline solution) as a moisturizing solution to fill the lens cup before it was placed in the eye; Group 2 included 15 patients (30 eyes) who used 0.18% sodium hyaluronate as a moisturizing solution. All patients underwent the following examinations: biomicroscopy of the anterior segment of the eye using a vital dye (0.1% fluorescein sodium) and assessment of the degrees of epitheliopathy of the conjunctiva and cornea according to the Oxford grading system, determination of the precorneal tear film break-up time (Norn test), as well as the status of total (Schirmer test) and basic (Jones test) tear production.

Results and discussion. Wearing scleral rigid gas-permeable contact lenses, regardless of the type of solution filled into the lens cup before placing it in the eye, improves significantly the ocular surface condition and increases the results of function tests.

Conclusion. The observed tendency towards a higher capacity to repair corneal tissues during the use of 0.18% sodium hyaluronate preservative-free tear replacement agent in the sublens space is confirmed by corneal confocal microscopy outcomes and indicates the greater efficacy of using a combination with a tear replacement agent.
Clinical and epidemiological aspects and modern approaches to the treatment of pityriasis versicolor
Authors: Matushevskaya E. V. , Ivanova M. A. , Shevchenko A. G. , Svirshchevskaya E. V.
Published: September 2024

Pityriasis versicolor (tinea versicolor) lichen (PVL) is a fungal infection of the stratum corneum of the epidermis caused by the yeast-like fungus Malassezia (Pityrosporum), which is part of the normal microbiome of the skin. Malassezia yeast has a conditionally pathogenic potential, penetrating into the stratum corneum and causing the appearance of multicolored spots on the skin. Malassezia fungi are involved in the pathogenesis of head and neck dermatitis, seborrheic dermatitis and folliculitis. PVL occurs in both tropical and temperate climates and affects both sexes equally. There are no systematic data on the prevalence of this disease in the world, but it is known that in tropical climates, PVL is more common (up to 40% in Brazil) than in temperate zones (<1% in Sweden). In Russia, there are also no general epidemiological data on the prevalence of PVL in the available literature. In the Krasnodar Territory in 2022-2024, among patients who turned to a dermatovenerologist for skin peeling accompanied by itching, 28% were diagnosed with PVL. The disease is considered non-contagious and is treated with topical antifungal drugs. In severe cases, the use of systemic antimycotics is indicated, which reduces the duration of the treatment and prevents relapses of the disease. The review provides data on the pathogenesis and prevalence of the disease, as well as modern approaches to PVL therapy.
COMPARATIVE ANALYSIS OF THE FATTY ACID COMPOSITION IN HUMAN, COW AND GOAT MILK AND THEIR INTERPOSITIONAL DISTRIBUTION IN TRIACYLGLYCEROLS
Authors: C. A. Ferreira Giovanna , D. Santos Patricia , S. Zangirolami Marcela , L. Figueiredo Alisson , S. Fernandes Cleverton , A. R. da Silva Geovane , A. Basso Ernani , O. Santos Oscar
Published: September 2024

Exploring the triacylglycerols composition in milk samples from different ruminant species is crucial for dairy product development. Identifying the fatty acid (FA) composition in human milk is essential and is usually performed using gas chromatography (GC). Heat maps are useful for visualizing these results, aiding in pattern identification and relationships between samples and variables. Additionally, nuclear magnetic resonance (NMR) spectroscopy provides important qualitative and quantitative information about fatty acids (FA). In the present study, we compare the fatty acid composition in samples of HM, cow milk, and goat milk, as well as to demonstrate their positional distribution in triacylglycerols (TAGs). Human milk contains 49.21% saturated fatty acids (SFAs), 34.32% monounsaturated fatty acids (MUFA), and 16.47% polyunsaturated fatty acids (PUFA), including 2.14% docosahexaenoic acid (DHA) and 13.02% linoleic acid (LA). On the other hand, cow and goat milk have higher proportions of SFAs (56.2 and 58.02%, respectively) and MUFAs (40.56 and 40.95%, respectively), but lower amounts of PUFAs (3.24 and 1.03%, respectively), with significantly lower quantities of DHA (0.03 and 0.43%, respectively) and LA (1.46 and 2.76%, respectively). Additionally, fatty acids in ruminant milk mainly consist of long-chain fatty acids (LCFAs), with oleic acid being the most abundant.
EMOÇÕES E ESTRATÉGIAS ADOTADAS POR BRASILEIROS E PORTUGUESES DURANTE A PANDEMIA DA COVID-19
Authors: Reis Lyria , Silva Ana Isabel Mateus da
Published: September 2024

Introdução: A pandemia da Covid-19 levou as pessoas a manifestarem emoções diferentes devido à situação que viviam, estas emoções bem como toda a situação de isolamento social levou a adoção de estratégias para se sentirem a nível físico e mental mais adaptadas e equilibradas no seu dia a dia. Objetivo: O presente artigo tem como objetivo analisar e descrever as emoções e as estratégias adotadas pela nossa amostra durante a pandemia da Covid-19. Metodologia: Este estudo faz parte de uma pesquisa mais ampla, realizada através de um questionário sociodemográfico com perguntas abertas e fechadas, efetuado no Google Forms, aplicado online em maio de 2020. Neste questionário foram abordadas as emoções e estratégias adotadas que estas pessoas desenvolveram durante a pandemia. A amostra foi de 438 participantes, 181 indivíduos portugueses(as) e 257 brasileiros(as). A análise de dados foi realizada através de estatística descritiva e análise de discurso. Resultados: Verificou-se que nos dois países, as emoções mais manifestadas foram medo e tristeza e as estratégias adotadas foram a criação de horários com rotinas diárias e o exercício físico. Conclusões: Este estudo contribuiu para conhecer emoções e estratégias adotadas desenvolvidos por brasileiros(as) e portugueses (as) durante a pandemia Covid-19.
Investigating the Probable Potential of Dihydropyridine Calcium Channel Blockers: Drug Repositioning in Cancer
Authors: Emami Kazemabad Mohammad Javad , Dadkhah Parisa alsadat , Amani Hanieh , Asgari Toni Sara , Izadi Alamshiry Mohammad Yasin , Shahrokhi Mehregan , Tizro Neda , Khani Samira
Published: September 2024

In contemporary medicine, cancers are recognized as significant concerns warranting attention.
Over time, scientific advancements have assisted physicians worldwide in exploring novel
approaches. Among these potential solutions are calcium channel blockers (CCBs), which hold
considerable importance and find extensive application across various medical conditions. CCBs,
classified as dihydropyridines and non-dihydropyridines, have been widely utilized in the management
of diverse cancer types. Given the diverse facets of dihydropyridine CCBs, our objective
was to comprehensively gather and summarize pertinent data regarding the impact of this medication
class on different cancer types.
A Review on Chandra Avaleha an Ayurvedic Formulation in Anidra (Insomnia)
Authors: Rahul Jaiswal  , Sharad Rathi  , Urmila Shukla  , Anshu Malviya
Published: September 2024

Avaleha Kalpana is a type of Kashaya Kalpana. It is made by boiling and evaporating herbal medicines or other liquids with sweeteners until the Kashaya reaches the appropriate confirmatory indicators mentioned in the Samhita. Various Avaleha Kalpana have been cited by Acharyas as recommended for various diseases and disorders. Chandra Avaleha is a poly herbal formulation used for the management of various diseases like burning sensation in the hands and feet, dizziness, mania, and insomnia. Its primary constituents include Shatavari Shankhapushpi, Vidarikand, and Kushmand, in equal quantity. Prakshep Dravya (Finely ground medicine powder) is also added. Insomnia (Anidra) is the disorder of inadequate or poor quality and also quantity of sleep either due to difficulty in initiation of sleep (sleep onset insomnia), difficulty in maintaining sleep because of frequently waking up in between (sleep maintenance insomnia) or waking up too early in the morning (sleep offset insomnia). Here an attempt is carried out to explore the action of Chandra Avaleha for insomnia.
A conceptual study of Aahar on Post Covid-19 complications
Authors: Priyanka Kumari  , Rohit Ranjan
Published: September 2024

The entire world has experienced many pandemics and epidemics, but occasionally a new one called SARS-CoV-2, or severe acute respiratory syndrome coronavirus, has put the global health care system under strain. Long Covid, or "long-haul COVID-19," refers to Post COVID-19 problems in individuals who recover from a COVID-19 infection, resulting in various complications such as cardiac, pulmonary, systemic, neuropsychiatric, tinnitus, acute kidney damage, renal failure, and thrombotic issues. After recovering from a COVID-19 infection, everyone must maintain a healthy diet because the infection may eventually harm their critical health. Ayurveda, a traditional healthcare system, emphasizes the importance of food and lifestyle in maintaining health and preventing diseases. Aahar is regarded as the "superior medicine," or Mahabhaisajya. Improper dietary habits lead to a variety of lifestyle health problems that can be avoided with appropriate Aahar and eating practices. According to Ayurveda, an individual's Prakriti, or constitution, should be taken into consideration when defining an Aahar. The article aims to assess a lot Aahar methods and concepts that are scattered over various Samhitas that can help manage Post COVID-19 complications and promote a quick recovery without future disease complications.
Ayurvedic intervention in the management of Keeta Visha (Wasp Bite) : A Case Report
Authors: Mitali Verma  , Urmila Shukla  , Kirti Sisodiya  , Shreya Sahu
Published: September 2024

Wasp stings are common, especially in populations living in vicinity to forested areas all over the world. Wasp is insects related to bees and ants. There are more than 20000 species or types of Wasps. Acharya Sushruta has explained Keeta Visha under Jangama Visha (Animate poison) and categorized 67 different types of Keeta under mainly 4 groups i.e., Vayavya Keeta, Agneya Keeta, Saumya Keeta, Sannipataka Keeta. viz, one each possessing the qualities of individual Doshas separately and one with the qualities of all the doses together. The main characteristics of insect bite are itching, burning sensation, erythema at the site of bite. Reaction to stings vary depending on the numbers of stings delivered & body`s reaction to venom in the sting. This is a case report of 27 years old female (student) residing in Bhopal, visited the OPD with the complaining of wasp bite on lateral aspect of arm just before 30 minutes prior to her visit. She had sharp pain, itching, redness, burning sensation at bite site. She was treated with Dushivishari Agad (500mg), Guduchiyadi Kashayam (500mg) and Yograja Guggul (250mg) and Lepa of Dushivishari Agad and Shatdhaut Ghrit for local application. The interventions controlled the poisoning, inferring that such cases can be successfully manage with Ayurvedic medicines.
An Ayurvedic approach for Non-alcoholic fatty liver associated with Type 2 Diabetes Mellitus: A Case report
Authors: Bhavya Khatri  , Gaurav Methil  , Harish Bhakuni  , Ajay Kumar Sahu
Published: September 2024

Background: The term Non-alcoholic fatty liver (NAFLD) refers to the accumulation of excessive fat inside the liver cells when excessive alcohol use is not present. The presence of both NAFLD and T2DM increases the likelihood of the development of complications of diabetes (including both macro- and micro- vascular complications) as well as augmenting the risk of more severe NAFLD, including cirrhosis, hepatocellular carcinoma and death. Liver illness is also described quite well in Ayurveda. NAFLD may be seen as a Santarpanotha Vikar (illness) bought on by Pittasthan, Raktavahasrotomoola, Kaphmedodusti and Sthanasamsraya in Yakrut (liver). Aim: To evaluate the efficacy of Ayurvedic intervention in NAFLD associate with T2DM. Method and material: In this case report, effect of Ayurveda intervention in grade III fatty liver is reported. Fifty -eight -year-old obese male with grade III fatty liver presented with fatigue, heaviness in abdomen, belching and incomplete bowel evacuation. On examination, there was no significant clinical abnormality except a high body mass index and haematological parameters. The patient was diagnosed sonologically with a grade III fatty liver. Observation and Conclusion: The patient was given Ayurveda treatment for two months. The patient was assessed for improvement in signs and symptoms, haematological parameters, and quality of life. Present case highlights the potential of Ayurveda interventions in managing non-alcoholic fatty liver disease with T2DM.
Ayurvedic management of Garbhasravi Vandhyatwa w.s.r. to Recurrent Pregnancy Loss - A Case Study
Authors: Princy Prabhu  , Sheela Mallikarjun  , Sridevi Swamy  , Ishwari Patil  , Sonalika Hiremath
Published: September 2024

Pregnancy is the start of an incredible journey that leads to great emotional fulfillment to women. Recurrent Pregnancy Loss (RPL) is defined as two or more failed clinical pregnancies confirmed by sonography or histopathology before 20 weeks. It is relatively common event occurring in 15-25% of pregnancies and increasing in prevalence with maternal age which in turn leads to infertility. The common causes of the first trimester abortion are genetic factors, immune and endocrine factors, infection and unexplained ones in the majority of the cases. In Ayurveda, based on clinical features Recurrent Pregnancy Loss can be correlated with Garbhasravi Vandhya mentioned in Harita Samhita and Putraghni Yonivyapath explained in Brihatrayees. Ayurveda describes many oral formulations along with Shodhana Chikitsa followed by Sthanika Chikitsas like Yoni Pichu, Yoni Poorana, Uttara Basti etc. giving effective sequel in Garbhasravi Vandhyatwa. Here, a mid aged 26 years old patient presenting with recurrent pregnancy loss was given with few oral medications and Shodhana Chikitsa i.e., Virechana Karma and Yoga Basti followed by Uttara Basti for her healthy uneventful pregnancy.
Assessment of Animal Welfare and Handling Procedures in the Slaughter of Sacred Animals During Eidul-Adha in Samarinda City
Authors: Wibowo Ari , Suhardi Suhardi , Fanani Anhar Faisal , Aprylasari Dede , Rahman Kamal , Anjani Fandini Melia , Chaijan Manat , Panpipat Worawan , Kim Siriporn Riebroy
Published: September 2024

The term "Qurban," originating from Arabic, denotes "close" and constitutes one of the annual religious rituals practiced by Muslims, involving the ritual slaughter of various livestock, including camels, goats, cows, sheep, and buffaloes. Nonetheless, concerns have arisen regarding the welfare and comfort of these animals during the slaughtering process. This research aimed to investigate welfare-oriented procedures employed in the slaughter of sacrificial animals and to identify and analyse the stress factors affecting them. The study was conducted across nine mosques in nine sub districts in Samarinda city on July 10-11, 2023, and involved a sample of 115 slaughtered cattle. The observational indicators included instances of falling and slipping, vocalization, states of consciousness and unconsciousness, and duration until death. The findings revealed that 36.52% of the animals experienced falls or slips, their vocalization levels reached 15.65%, surpassing the anticipated threshold of 5%, consciousness and unconsciousness indicators were observed in 56.09% of the cases, and the longest duration until death fell within the range of 10-12 minutes. These findings highlight a lack of consideration for animal welfare during sacrificial animal slaughtering practices in Samarinda city mosques.
An Advanced Machine Learning Model for a Web-Based Artificial Intelligence–Based Clinical Decision Support System Application: Model Development and Validation Study
Authors: Lin Tai-Han , Chung Hsing-Yi , Jian Ming-Jr , Chang Chih-Kai , Perng Cherng-Lih , Liao Guo-Shiou , Yu Jyh-Cherng , Dai Ming-Shen , Yu Cheng-Ping , Shang Hung-Sheng
Published: September 2024

Background

Breast cancer is a leading global health concern, necessitating advancements in recurrence prediction and management. The development of an artificial intelligence (AI)–based clinical decision support system (AI-CDSS) using ChatGPT addresses this need with the aim of enhancing both prediction accuracy and user accessibility.

Objective

This study aims to develop and validate an advanced machine learning model for a web-based AI-CDSS application, leveraging the question-and-answer guidance capabilities of ChatGPT to enhance data preprocessing and model development, thereby improving the prediction of breast cancer recurrence.

Methods

This study focused on developing an advanced machine learning model by leveraging data from the Tri-Service General Hospital breast cancer registry of 3577 patients (2004-2016). As a tertiary medical center, it accepts referrals from four branches—3 branches in the northern region and 1 branch on an offshore island in our country—that manage chronic diseases but refer complex surgical cases, including breast cancer, to the main center, enriching our study population’s diversity. Model training used patient data from 2004 to 2012, with subsequent validation using data from 2013 to 2016, ensuring comprehensive assessment and robustness of our predictive models. ChatGPT is integral to preprocessing and model development, aiding in hormone receptor categorization, age binning, and one-hot encoding. Techniques such as the synthetic minority oversampling technique address the imbalance of data sets. Various algorithms, including light gradient-boosting machine, gradient boosting, and extreme gradient boosting, were used, and their performance was evaluated using metrics such as the area under the curve, accuracy, sensitivity, and F1-score.

Results

The light gradient-boosting machine model demonstrated superior performance, with an area under the curve of 0.80, followed closely by the gradient boosting and extreme gradient boosting models. The web interface of the AI-CDSS tool was effectively tested in clinical decision-making scenarios, proving its use in personalized treatment planning and patient involvement.

Conclusions

The AI-CDSS tool, enhanced by ChatGPT, marks a significant advancement in breast cancer recurrence prediction, offering a more individualized and accessible approach for clinicians and patients. Although promising, further validation in diverse clinical settings is recommended to confirm its efficacy and expand its use.
Discurso sobre las mujeres migrantes en canciones populares: relatos de vulnerabilidad y supervivencia
Authors: Torres Osuna Cristian Daniel
Published: September 2024

La movilidad humana ha sido abordada desde diversas corrientes científicas en numerosas ocasiones, puntualizando sus rasgos, raíces, conflictos y horizontes de futuro; consecuentemente, el banco de datos derivado de extensos trabajos de campo ha expuesto análisis fundamentales para su entendimiento desde las ciencias sociales. Por lo tanto, en la presente entrega académica, intentaremos contribuir con el robustecimiento del objeto de estudio, escudriñando en la relación del fenómeno con las mujeres migrantes, a través de los discursos que de ellas se desprenden en temas musicales populares de la plataforma YouTube. Los temas musicales actúan como trasmisores de contenidos discursivos simbólicos, los cuales desarrollan y distribuyen perspectivas heterogéneas sobre temáticas nacionales e internacionales; en ese contexto, en el presente artículo aplicaremos un análisis crítico a los discursos de las canciones: Mujer migrante – Pacha La Hija Del Sol; Mujer frontera – Clara Peya, feat. Alba Flores y Ana Tijoux; Me fui – Reymar Perdomo, y, Homenaje a Claudia Gómez – Escandalosos Musical, sumando varios millones de reproducciones en YouTube, y desplegándose como temática central los procesos y complicaciones de mujeres migrantes; haciendo hincapié en sus peculiaridades y vínculo con los andamiajes teóricos sobre la migración, y, mostrando escenarios en los cuales las mujeres migrantes se desenvuelven en la pobreza, vulnerabilidad, separación familiar, inseguridad laboral, peligros del tránsito, duros controles migratorios, deportación, asesinatos, por mencionar solo algunos.
A conceptual model of the role of the instructor in fostering students’ mathematical creativity
Authors: Yaftian Narges
Published: September 2024

Several studies tried to introduce some of the efficient factors that can influence fostering mathematical creativity in learning environments. since some of the variables associated with mathematical creativity in educational environments depend on the culture, conducting research in this area seems necessary. It should be noted that the contribution of Iranian researchers to these studies is very small. The paper aims to study the role of instructors in nurturing creativity in mathematics students from math students’ point of view and to present a conceptual model. The research is a qualitative study conducted using grounded theory. Participants were selected from university students who are studying mathematics in the universities of the city of Tehran in Iran using purposive sampling and the sampling is stopped until theoretical saturation. Finally, semi-structured in-depth interviews were conducted with 10 students. Interviews were audiotaped, transcribed, and coded in the two stages of free coding and axial coding. Classification of codes led to numerous categories. The findings show that instructors can influence several aspects: belief, intention, mathematical knowledge, mathematical thinking, and personality characteristics such that being persistent, being a risk taker, and forgetting fixation.
Determinants of Health Behaviors Among University Students: Insights from a Cross-Sectional Study in the Karaganda Region
Authors: Yandutkina Karina , Nukeshtayeva Karina , Bolatova Zhanerke , Dauletkaliyeva Zhaniya , Kayupova Gaukhar , Takuadina Aliya , Yerdessov Nurbek , Zhamantayev Olzhas , Zhanalina Gulmira , Shintayeva Nurzhamal , Rogova Svetlana
Published: September 2024

Health, a holistic concept encompassing physical, mental, and social well-being, stands as a fundamental value in every individual's life. Despite its paramount importance, many scholars highlight the insufficient commitment to a healthy lifestyle among student populations, often attributed to the challenges associated with academic transitions and social adjustments. Understanding the factors influencing student health behaviors is crucial for promoting well-being and fostering healthy lifestyles. This study employed a cross-sectional, retrospective analysis using primary data. The survey covered socio-economic factors and aspects of a healthy lifestyle among students from various universities in the Karaganda region, including Medical, Technical, and Humanitarian universities. Multiple logistic regression analysis was conducted to identify determinants influencing students' health behaviors. Demographic analysis revealed that surveyed students were primarily urban-born, enrolled in medical university programs, and predominantly lived with parents or relatives. Most students reported financial capacity for medical care and rated their social standing favorably. A significant proportion exhibited a normal BMI, with a notable prevalence of chronic diseases. While emergency care utilization varied, general practitioner visits were common, albeit less frequent among students with chronic conditions. Factors influencing health behaviors included educational program enrollment, socio-economic status, residential circumstances, gender, age, vaccination status. Understanding the complex interplay of factors influencing student health behaviors is essential for designing effective health promotion programs within universities. This study provides valuable insights into the determinants of health behaviors among students, shedding light on areas for intervention and emphasizing the importance of fostering a healthy lifestyle for overall well-being and academic success.

 

 
Atatürk Döneminde Temel Çocuk Hakları (1923-1938)
Authors: Cansız Demet
Published: September 2024

Cumhuriyetin ilanından sonra memleket dahilindeki en büyük problemlerden biri de toplumsal, siyasi, sosyal ve hukuki açılardan ele alınmayı bekleyen çocuk meselesi idi. Trablusgarp, Balkan ve I. Dünya Savaşları ile çocuk sorunlarında gözlemlenen artışlar Millî Mücadele döneminde de devam etmiş, özellikle çocuk himayesi meselesi ihmal edilemeyecek boyutlara ulaşmıştı. Üstelik 20. yüzyılda tüm dünyadaki siyasi gelişmeler çocuğu yalnızca küçük bir birey olmaktan çıkarıp, onu nüfusun devamlılığı, ülkelerin gelişmişliği, refah düzeyi, statüsü gibi stratejik konularla doğrudan bağlantılı hale getirmişti. Bir “beka meselesi” şeklinde değerlendirilen çocuğun, sorun ve ihtiyaçlarına kalıcı çözümler üretmek bu noktada zaruri bir hâl almıştı. Cumhuriyetin ilanından sonra bu mesele uluslararası düzeyde takip edilerek çocukların bilhassa beslenme, bakım, himaye, sağlık, eğitim, çalışma gibi temel ihtiyaçlarına yönelik düzenlemeler yapıldı. Söz konusu süreçte Osmanlı’dan Cumhuriyet’e nakleden hayır kurumları, kurumlar üzerinden geliştirilen yeni politikalar, çıkarılan yasalar, alınan tedbirler ve denetimlerle çocukların temel hak ve ihtiyaçları gözetildi. Bu çalışmada Atatürk döneminde iç ve dış gelişmeler neticesinde üretilen çocuk politikaları arşiv ve basın kaynakları ile ilgili literatür üzerinden çok yönlü bir şekilde değerlendirilmeye çalışıldı.
Necip Melhame’nin Gölgesinde Bir İsim: Selim Raad Efendi
Authors: Yadi Ahmet
Published: September 2024

19. yüzyılda Tanzimat ve Islahat fermanlarıyla birlikte Osmanlı bürokrasisinde gayrimüslimler kendilerine daha çok yer bulmaya başladılar. Sultan II. Abdülhamid devrinde bürokrasideki gayrimüslim sayısında önemli bir artış olmuştur. Bu dönemde özellikle Arapların bürokraside yer alması dikkate değerdir. Bunlar içerisinde Selim ve Necip Melhame kardeşler öne çıkanlar arasında yer almaktadır. Selim Raad Efendi ise Necip Melhame’nin kayınbiraderi olup Osmanlı bürokrasisinde akrabalık ilişkisi neticesinde yer edinmiştir. İlk görevi eniştesi Necip Melhame’nin başında bulunduğu Bulgaristan Komiserliği Fransızca başkatipliğidir. Necip Melhame’nin Bulgaristan Komiserliği’nden ayrılmasını müteakip kendisi de göreve devam etmemiştir. Daha sonra Şûrâ-yı Devlet azalığına atanmıştır. Bu görevdeyken Bulgaristan’daki bazı meselelerin halledilmesi için görevlendirilmiştir. Ayrıca Beyrut Elektrikli Tramvay İmtiyazını almıştır. Kendisi II. Abdülhamid Dönemi’nde Necip Melhame’nin adamı olarak tanınmıştır. Nitekim II. Meşrutiyet’in ilanıyla Melhame ailesine karşı yoğun baskı ve suçlamalar yapıldığı sırada Selim Raad Efendi memuriyetten çıkarılmıştır. 1917 yılında Necip Melhame ve Selim Raad Efendi, hükümeti değiştirmeye yönelik bazı faaliyetlerde bulunduğu gerekçesiyle Beyşehir’e sürgün edilmişlerdir. Daha sonra kendilerine istedikleri yere gitme hakkı verilerek serbest bırakılmışlardır.
Çalışmada Selim Raad Efendi’nin Necip Melhame ile olan akrabalık bağı sayesinde hangi görevlerde bulunduğu ele alınmaya çalışılmıştır. Çalışmanın ana kaynaklarını Osmanlı arşiv kayıtları ile birlikte süreli yayınlar oluşturmaktadır.
Validez y confiabilidad en la investigación cualitativa
Authors: Perez Ripossio Ramiro Nicolas
Published: September 2024

El artículo discute los modos de aplicar criterios de rigor y calidad en la investigación cualitativa. La precisión metodológica de los estudios cualitativos es un tema de importancia, aunque no suele plantearse como parte de las condiciones necesarias para llevarlos a cabo. En la investigación cuantitativa se emplean los criterios de validez y confiabilidad entendiendo que el primero significa la adecuación semántica entre un concepto (abstracción) y un indicador (referente empírico). Mientras que la confiabilidad o fiabilidad es la consistencia de los resultados obtenidos ante sucesivas mediciones. Para debatir esta cuestión se toma como ejemplo una investigación doctoral sobre la migración de las travestis/trans sudamericanas que residen en el Área Metropolitana de Buenos Aires. Se indica de qué manera los diferentes criterios de rigor y calidad fueron aplicados teniendo en cuenta lo alcances y limitaciones del estudio en función de estos criterios.
El acceso a la información pública en la Argentina: experiencias de investigación sobre políticas de medios y TIC
Authors: Califano Bernadette
Published: September 2024

En este trabajo se explora el ejercicio del derecho de acceso a la información pública en su vínculo con la investigación académica, a partir del análisis de tres experiencias. Los tres casos se enmarcan en investigaciones más amplias sobre políticas de comunicación, llevadas adelante entre 2008 y 2022 en Argentina, en las que se recurrió a solicitudes de acceso a la información pública en manos del Estado. Cada una de estas investigaciones se produjo dentro de contextos sociopolíticos y normativos disimiles, y obtuvo resultados dispares con respecto a las respuestas estatales. Sin embargo, todas las experiencias resultan ilustrativas de las dificultades y desafíos que persisten para el efectivo ejercicio del derecho de acceso a la información.
Fiestas nacionales e identidades locales en el norte de la Patagonia
Authors: Monasterio Julio César
Published: September 2024

El presente trabajo centra su atención en el análisis de las estrategias de oficialización de las Fiestas nacionales que se desarrollan en el territorio de la Patagonia norte. Para esto, se indaga en documentos normativos y mediáticos con la finalidad de observar cómo se configuran elementos simbólicos que se presentan como distintivos de las celebraciones festivas de la región en lo que hace a la conformación de tradiciones e identidades locales. En esta clave, se examina, en los documentos mencionados cómo se pone en juego la relación entre cultura, costumbres, tradiciones y recursos históricos para la construcción de personajes y prácticas típicas festivas.
Recent Advances in Water-Soluble Edible Pouches: Production Methods, Industrial Applications, and Legal Regulations
Authors: Dadaş Aslıhan Begüm , Demircan Bahar , Velioğlu Yakup Sedat
Published: September 2024

Food packaging, crucial for protecting foods from various environmental impacts, is commonly produced from petroleum and its derivatives. However, the slow decomposition of plastics in nature leads to environmental pollution. One of the alternatives presented as a solution to this problem is biodegradable packaging materials. In this context, edible films stand out as a new packaging material with various non-toxic and environmentally degradable features. Edible films offer an eco-friendly option with properties like oxygen and moisture barriers. Recently, the production of pouches derived from these edible films has gained popularity. Edible pouches are designed as an alternative to the environmental pollution caused by disposable materials arising from practical usage demands. These pouches stand out as packaging with controlled release properties and their ability to dissolve in water, aiding in preserving the enclosed foods. This review examines edible films' purpose, characteristics, and applications, focusing on the use and functions of pouches derived from edible films. Additionally, the review discusses the experimentation of these pouches in various products, production purposes, methods, manufacturers, and the legal regulations associated with them.
Geological position and composition of sandstones in the Listvenny and Marcheta Formations of the Zasur’ya Series, Gorny Altai
Authors: Krutikova A. K. , Safonova I. Yu. , Obut O. T. , Perfilova A. A. , Savinskiy I. A. , Gan B.
Published: September 2024

Research subject. Sandstones in the Listvenny and Marcheta Formations of the Zasur’ya Series, Gorny Altai. Aim. Reconstruction of the parent rocks and geodynamic position of the sedimentation basin of sandstones of the Zasur’ya Series. Materials and Methods. The stratigraphic position of greywackes was studied. Petrographic descriptions were carried out using whole-rock compositions obtained by X-ray fluorescence (XFR) analysis. The obtained data were analyzed; classification diagrams were compiled. Results. The geological position of the sandstones of the Listvenny Fm. (Molchanikha Locality) and Marcheta Fm. (Marcheta Locality) shows their sediments as part of an accretionary complex. Planar and vertical cross-sections for both localities were constructed. According to petrographic and geochemical data, the sandstones correspond to greywackes, i.e., first-cycle sedimentation rocks. The provenance of the Listvenny sandstones was dominated by intermediate and felsic rocks. The provenance of the Marcheta sandstones was dominated by mafic to intermediate igneous rocks. Conclusions. According to the studied geological and geochemical data, the greywackes of the Listvenny and Marcheta fms. were formed by destruction of an intra-oceanic arc. The sandstones of the Listvenny Fm. accumulated in a back-arc basin, and the sandstones of the Marcheta Fm. accumulated in a forearc basin.
A Comprehensive Review of Intelligent Reflecting Surfaces from Hardware to Industrial Integration and Future Directions
Authors: Munira Anne , Muguro Joseph , Njeri Waweru
Published: September 2024

An Intelligent Reflecting Surface (IRS) has emerged as a key solution to performance bottlenecks in wireless communication. Its ability to combat multipath fading and improve signal and energy efficiencies has made it relevant to various industry applications, including the Internet of Things (IoT), smart manufacturing, cognitive radio, radar, and Multiple-Input Multiple-Output (MIMO) systems. This paper presents a comprehensive review of the IRS’s structure and hardware requirements, channel estimation, optimization methods, and key applications to enable readers to understand how the IRS operates, its benefits, and some of the challenges involved in its application. The structure and hardware requirements are important to understand as they dictate the material composition, number, and arrangement of reflecting elements, and their reconfigurability. Channel State Information (CSI) plays a crucial role in optimized transmission as it gives information on the channel conditions, enabling users to tailor their transmission accordingly. In this work, all scholarly papers related to the IRS published between 2010-2024 were considered, sampled, and categorized based on the key themes. An analysis of the hardware and architecture reveals that transceiver hardware imperfections significantly affect IRS optimization and should be considered. While several channel estimation techniques offer comparable benefits, accuracy turns out to be the most important factor to consider. Further, results show that flexibility and inference accuracy make machine learning techniques superior to other optimization methods. Still, challenges remain in relation to IRS standardization, privacy concerns, and handover techniques that ought to be addressed for future industrial integration.
WORK DISCIPLINE AND MOTIVATION ON JOB SATISFACTION
Authors: Syardiansah Syardiansah , Chandra Riny , Lestari Ayu
Published: September 2024

This research aims to determine the influence of work discipline and motivation on job satisfaction of the Satpol PP and Wilayatul Hisbah East Aceh units. The samples in this research were 81 employees in the Satpol PP and Wilayatul Hisbah East Aceh units. Data were analyzed using multiple liner regression tests, t tests, F tests, normality tests, heteroscedasticity tests, classical assumption tests and hypothesis tests. Based on the results of the t test, it was found that work discipline had a positive and significant influence on job satisfaction, motivation had a positive and insignificant influence on job satisfaction. And the results of the F test show that work discipline and motivation simultaneously have a positive and significant effect on job satisfaction. From the results of the coefficient of determination test, it was found that 43% of the work discipline and motivation variables could explain the job satisfaction variable, while the remaining 57% could be explained by other variables that were not included in this research such as work environment, compensation, etc.
FORECASTING THE IMPACT OF CONTROL ACTIONS ON THE SECTORAL STRUCTURE DYNAMICS OF A LABOR MARKET BASED ON THE BALANCE MATHEMATICAL MODEL
Authors: Невечеря А.П. , Попова Е.В.
Published: September 2024

Предложен подход к учёту управляющих воздействий на динамику отраслевой структуры рынка труда при прогнозировании показателей отраслевой занятости. Применяемая схема прогнозирования основана на балансовой математической модели межотраслевых перемещений трудовых ресурсов. В рассмотренном ранее одним из авторов варианте схемы прогнозирования тренды показателей, характеризующих межотраслевую мобильность рабочей силы, определялись независимо друг от друга. В настоящей работе осуществлена модификация данной схемы: предложен способ группировки показателей межотраслевых перемещений и критерий определения общего тренда показателей внутри каждой группы. С помощью модифицированной схемы прогнозирования вычислены прогнозы отраслевой занятости на рынке труда РФ в 2011–2016 гг., произведено сравнение с ранее полученными результатами. По данным отраслевой занятости и безработицы за 2017–2021 гг., предоставляемым согласно классификатору ОКВЭД-2, осуществлён прогноз ожидаемого уровня занятости в конце 2022 г. На примере рынка труда РФ в 2017–2022 гг. рассмотрен способ определения результатов управления: продемонстрированы изменения прогнозов отраслевой занятости в случае учёта управляющих воздействий на аграрный и промышленный сектора исследуемого рынка.

This paper proposes an approach to considering control actions on the sectoral structure dynamics of a labor market when forecasting sectoral employment indicators. The forecasting scheme is based on the balance mathematical model of inter-sectoral labor resource movements. In the forecasting scheme considered previously, the trends of indicators characterizing inter-sectoral labor force mobility were determined independently of each other. In what follows, this forecasting scheme is modified by introducing a grouping method for the indicators of inter-sectoral labor resource movements and a criterion for determining the general trend of indicators within each group. The modified forecasting scheme is applied to calculate sectoral employment forecasts for the labor market of the Russian Federation in 2011–2016, and the forecasts are compared with the previous results. The expected employment rate is forecasted for the end of 2022 using sectoral employment and unemployment data for 2017–2021 according to the second edition of the All-Russian Classifier of Types of Economic Activity (OKVED). A method for determining the result of control actions is presented on an example of the Russian Federation labor market in 2017–2022: changes in the sectoral employment forecasts are demonstrated in the case of considering control actions on the agricultural and industrial sectors of the market.