bluuebunny/crossref_metadata_2025 huggingface dataset:
Audit TI Pada PT Sinar Aceh Menggunakan Framework Cobit 4.1
Authors: Andry Johanes Fernandes , Riwanto Rengga Eko
Published: September 2020

PT Sinar Aceh adalah perusahaan yang bergerak di bidang garmen, khususnya underwear, menggunakan TI untuk mengintegrasikan antara berbagai divisi intern dan cabang dengan pusat untuk memenuhi kebutuhan dan tujuan bisnis perusahaan. Evaluasi tata kelola teknologi informasi menggunakan COBIT. Evaluasi dilakukan terhadap kinerja intern divisi TI, sehingga dapat meningkatkan kinerja dalam mencapai tujuan bisnis perusahaan.  Fokus penelitian dilakukan pada domain ME. Hasil dari audit ini adalah rekomendasi yang tepat untuk tata kelola TI pada perusahaan sesuai dengan COBIT framework 4.1. Hasil penelitian ditemukan bahwa tingkat kematangan Tata Kelola TI pada Perusahaan pada level 0.85. Artinya ada bukti bahwa perusahaan telah mengakui bahwa ada masalah dan perlu ditangani. Namun demikian, tidak ada proses standar. Pendekatan keseluruhan untuk manajemen tidak teratur. Tingkat kematangan yang ada saat ini berada di bawah tingkat kematangan yang diharapkan, sehingga perlu diperbaiki di level yang diharapkan. Untuk mengatasi gap yang ada telah direkomendasikan beberapa langkah yang harus dilakukan.
Perancangan Sistem Informasi Data Pelayanan Pengunjung Berbasis Web menggunakan Framework CodeIgniter dan UIkit (Studi Kasus: Perpustakaan dan Arsip Daerah Kota Salatiga)
Authors: Oktami Adinda Setya , Mailoa Evangs
Published: September 2020

Pengunjung merupakan hal yang penting bagi Perpustakaan. Untuk mendapatkan pengunjung yang banyak diperlukan layanan yang tersedia bagi pengunjung. Perpustakaan dan Arsip Daerah Salatiga (Persipda) adalah salah satu perpustakaan di Salatiga yang memiliki banyak pengunjung dan menyediakan berbagai layanan pengunjung. Data pelayanan pengunjung merupakan hal yang penting untuk mengetahui tingkat kualitas pelayanan.  Kualitas pelayanan dapat diketahui dengan terjadinya peningkatan atau penurunan jumlah pengguna suatu layanan. Oleh karena itu dibutuhkan sistem informasi data pelayanan pengunjung untuk mengelola data di pelayanan serta mengetahui terjadinya peningkatan atau penurunan jumlah pelayanan pengunjung. Sistem informasi ini dilengkapi fitur highchart untuk menampilkan data pengunjung dalam bentuk chart yang ada di database sistem.           
AUDIT SISTEM INFORMASI PADA PT WALEPAY FINANSIAL TEKNOLOGI MENGGUNAKAN KERANGKA KERJA COBIT 4.1 DAN BALANCED SCORECARD
Authors: Wijaya Roby , Honni Honni , Pratama Hendry
Published: September 2020

PT Walepay Finansial Teknologi adalah sebuah perusahaan dibidang teknologi finansial (tekfin). Pada perusahaan ini penulis ingin mengetahui seberapa baik penerapan tata kelola yang sudah dijalankan oleh PT Walepay Finansial Teknologi. Dengan menggunakan kerangka kerja COBIT 4.1 dan BSC Model. Penulis akan mengukur tingkat kematangan pada bagian penerapan pengaturan dan perencanaannya. Penulis menggunakan 10 domain yaitu PO1, PO2, P03, PO4, PO5, PO6, PO7, PO8, PO9 dan PO10. Untuk BSC modelnya, penulis menggunakan perspektif internal perusahaan. Untuk tingkat kematangan didapat pada domain PO1 dan PO6 dengan nilai 3, sedangkan terendah terdapat pada domain PO7 dengan nilai 1,5. Rekomendasi untuk domain PO adalah mematangkan lagi rencana penerapan TI pada perusahaan, terutama dalam menetapkan hubungan proses TI dengan organisasi, memaksimalkan investasi TI yang ada, serta lebih memperhatikan lagi resiko resiko yang ada dari kehadiran TI. Berdasarkan hasil yang didapatkan penulis, penulis memberikan saran kepada perusahaan untuk memperhitungkan resiko TI pada masa mendatang agar perencanaan perusahaan kedepannya lebih baik. Penulis juga menggunakan Balanced Scorecard untuk melihat perspektif dari proses bisnis internal dan perspektif pembelajaran, dan pertumbuhan. Dari perspektif proses bisnis internal, perusahaan sudah cukup baik dalam menjalankan proses bisnis, sedangkan dari perspektif pembelajaran dan pertumbuhan, perusahaan juga sudah cukup baik. Rata-rata dari hasil kesepuluh domain PO adalah 2,25 yaitu dalam tahap Repeatable but Intuitive.
Segmentasi Popularitas Akun Youtube Menggunakan Metode ID3
Authors: Sudarsono Bernadus Gunawan , Saputra Rahma , Utomo Ferik , Wijaya Christian
Published: September 2020

Internet bukan merupakan hal yang awam di era digital seperti ini, hampir disetiap kalangan dunia dapat mengakses internet dengan mudah. Dengan akses internet  yang mudah didapatkan  hampir seluruh kalangan masyarakat di Indonesia, membuat masyarakat mudah mengakses media sosial yang tersedia didalam internet. Salah satu media yang menyediakan tontonan atau video dengan berbasis internet adalah Youtube. Youtube berdiri sejak tahun 2005, namun baru populer dan dapat diakses oleh masyarakat Indonesia secara luas dalam beberapa tahun terakhir. Didalam youtube terdapat data-data mengenai aktivitas didalam youtube itu sendiri, terutama adalah data mengenai channel youtube yang memiliki jumlah subscriber, total views, dan lain-lain. Didalam jurnal ini kami akan membahas mengenai grade yang didapatkan oleh suatu channel youtube dengan dilakukannya pengolahan Big Data mengenai channel youtube. Metode penelitian yang dilakukan adalah metode penelitian deskriptif dimana data akan diolah untuk membuat deskripsi secara sistematis,faktual, serta akurat pada fakta atau sifat populasi tertentu. Penelitian bertujuan untuk menguji tingkat popularitas beberapa channel youtube dari banyaknya upload serta pelanggan dan juga banyaknya orang yang melihat video. Hasil penelitian menunjukan bahwa adanya tingkat popularitas (yang dinilai berdasarkan view, subscriber, dan upload) dari total 5001 channel youtube yang berbeda dapat yang mempunyai urutan sebagai berikut : (A++,A+,A,A-,B+)
The substantiation of differentiated therapy of the combined disgormonal pathology of reproductive organs in women of reproductive age with comorbid conditions
Authors: Shurpyak S. О.
Published: September 2020

The objective: substantiation of the differentiated therapeutic approaches to the treatment of the combined dyshormonal pathology of the reproductive organs, taking into account the comorbidity of the patients.Materials and methods. The study involved 300 women of reproductive age (20 - 42 years, an average of 29.9±5.6 years). The examination included ultrasonographic examination of the pelvic organs, mammary glands, thyroid gland, determination of the levels of pituitary tropic hormones and ovarian steroid hormones, thyroid hormones, antibodies to thyroperoxidase, serum levels 25 (OH) D. Results. Obesity of varying degrees was observed in 31.0% of the patients examined. The prevalence of autoimmune thyroiditis in patients with a dyshormonal pathology of the reproductive system was 36.0%, and subclinical hypothyroidism was diagnosed in 21.3% of women, but among patients with autoimmune thyroiditis, the incidence of subclinical hypothyroidism was 59.3% with 3.7% of manifest hypothyroidism. Insufficiency of vitamin D was detected in 34.0% of patients with dyshormonal pathology, vitamin D deficiency in 44.3%, severe deficit in 21.7%. Сonclusions. The use of complex differentiated pharmacotherapy for treatment of combin dyshormonal pathology of reproductive organs with correction of comorbid states allows to achieve a higher efficacy in comparison with usual practice (normalization of MCs 97.2% at 73.3%, reduction of pain syndrome 94.7% at 60.6% and cyclic mastodynia – 93,9% at 43,9%, reduction of vegetative-vascular and non-specific symptoms – 94,8±3,9% at 24,3±16,7%), to reduce the frequency of relapses during 6 months of observation from 14, 5% to 4.1% (p=0.0128), to achieve the desired pregnancy without stimulants and the ART and ovulation in 64.1% of patients compared with 30.6% (p=0.0079) in case of usual practice.
MODELING AND MANAGING MEDICAL DATA
Authors: Geger Emilia , Kozlova Irina
Published: September 2020

The article describes a statistical method for analyzing medical data based on the comparison of binary samples. Processing data that is accumulated in transactional medical information systems, based on the analysis of binary samples, allows you to determine the indicators of laboratory research and diagnoses that are characteristic of harmful production factors. This will contribute to the development of digital technologies in healthcare, which will improve both diagnostics and treatment methods, as well as facilitate the adoption of competent management decisions. The research results were converted to binary form by comparing them with the statistical norm interval. Diagnoses were considered initially as a binary variable. The samples obtained as a result of binarization for two groups, the first group includes people whose production activities contain harmful factors, and the second – those who do not have these factors, were compared with each other. The initial group turned out to be heterogeneous in relation to the other group, so it was decided to conduct a further study based on the development and testing of methods for adjusting samples in order to achieve uniformity while maximizing the preservation of medical data used for analysis.
URBAN MOVEMENT ROUTES ESTIMATION FOR OPTIMAL URBAN DRIVING
Authors: Azarchenkov Andrey , Marchenkov Nikolai
Published: September 2020

We consider the factors influencing the choice and assessment of the quality of the route in the road network. A formula is proposed for assessing the quality of a route in the road network in terms of optimizing the path between two points. The model was tested on 60 created graphs. With their help, the optimal parameters of the user model were selected. Methods for setting the parameters of the considered model are proposed for the developed formula. The resulting model has a moderate complexity in assessing the quality of the route and its software implementation, while simultaneously covering the most important characteristics of the road network and supporting efficient pathfinding on the graphs of the road network. It also provides good customization of the model.
Comparison of Time spent between an electronic and a paper-based laboratory information system by laboratorians at a polyclinic in Greater Accra, Ghana: A time-motion study
Authors: Boakye Philip
Published: September 2020

The acceptance of electronic laboratory information system (LIS) is
gradually increasing in developing countries. However, the issue of time
effectiveness due to computerization is less clear as there is fewer
accessible information. One of the key issues for laboratorians is their
indecision with LISs’ would-be effect of time on their work. A polyclinic in
Ghana was in the process of implementing electronic LIS. Several of the
laboratorians did not have knowledge and skill in computing and there
were disagreeing views on the time effectiveness of the LIS after
implementation. The management of the polyclinic laboratory was
concerned to assess time advantageousness of recording data when
using the electronic LIS compared with paper-based LIS.

Five randomly selected laboratorians were provided two sheets of paper
with tables to document the time they spent for both paper-based and
electronic LIS. Data were collected for a total of 230 records,115
electronic LIS and 115 paper-based LIS. The t-test (mean-comparison
test) was computed to compare the means of both electronic and paperbased LIS times.

There was a statistical significant difference in the time spent between
electronic and paper-based LIS. The time spent between paper-based
and electronic LIS was 0.41 minutes (95% CI 0.15 to 0.66) longer than
in electronic LIS.

LIS can be adopted in polyclinics without having significant negative
impact on time spent between electronic and paper-based LIS. More
time–motion studies that include laboratorians are however necessary in
order to get a more complete picture of time spent between electronic
and paper-based LIS.
Determination of botanical composition of Çamlıhemşin-Trovit plateau
Authors: ÇATAL Muhammed İkbal , BAYKAL Hüseyin , BAKOĞLU Adil
Published: September 2020

Botanical and floristic composition studies are carried out in order to have information about the vegetation of the pastures. In this study, canopy covering and botanical composition ratios and pasture condition class were examined. Botanical composition measurements were made in Trovit plateau of Çamlıhemşin district of Rize province. Botanical composition study was determined by using Lup method which is used in vegetation measurements. In the lup measurements, 5 main lines and 10 lines on the each main line were determined. As a result of the study; 4 Poaceae, 2 Fabaceae and 32 taxon from other families were identified. The rate canopy covering of the research area was 79.15%, the rate of Poaceae in the botanical composition was 21.24%, the rate of the Fabaceae 13.66% and rate of the other families 65.10%. The pasture condition was found to be weak with 2.365 pasture degree. It was concluded that especially controlled grazing and top-seeding, were applied together other methods of breeding.
EXAMINATION OF PRIVATE HEALTH INSURANCE IN TERMS OF HEALTH SERVICES USAGE IN TURKEY
Authors: GÜDÜK Özden , TARIM Mehveş
Published: September 2020

In this study, it is aimed to investigate whether there is any difference between health services usage of individuals with and without private health insurance in Turkey. If there is a difference, it is aimed to find in which direction does it affect and what kind of health care does it direct individuals to. A total of 852 people, 459 of whom do not have private health insurance and 393 of whom have private health insurance have been surveyed by the researchers using a questionary that was created by literature review. Participants were asked questions about their socio-demographic, economic, health status and use of health services in the last year. The data obtained were analyzed with SPSS package program. In the analysis, non-parametric techniques such as Mann Whitney U test and Chi square were used. Significant differences were found between the individuals with and without private health insurance in terms of outpatient treatment, surgical procedure, vaccination, dentist visits, glasses-contact lenses supply and family health center (FHC) visits. It has been found that individuals with private health insurance tend to use therapeutic health services rather than preventive health services. Also, the usage of primary health care in this group is lower.
EXAMINATION OF PRIVATE HEALTH INSURANCE IN TERMS OF HEALTH SERVICES USAGE IN TURKEY
Authors: GÜDÜK Özden , TARIM Mehveş
Published: September 2020

In this study, it was aimed to investigate whether there was any difference of the usage of health services between individuals who had and had not private health insurance in Turkey. If there was any difference, which direction it effects and what kind of health care it directs individuals toward. A questionary was created by author depending on literature review. There were questions about participants’ socio-demographic, economic and health status and the usage of their health services in the last year. The sample was consisted of 852 people, 459 of whom do not have private health insurance and 393 of whom have private health insurance. The data was analyzed with SPSS.v2 package program. Non-parametric tests such as Mann Whitney U test and Chi square were used for the analyzing. Significant differences in terms of outpatient treatment, surgical procedure, vaccination, dentist visits, glasses-contact lenses supply and family health center (FHC) visits were found between the groups. It was found that individuals who had private health insurance tend to use therapeutic health services rather than preventive health services. Also, the usage of primary health care in this group was lower than others.
USING AUTHENTIC MATERIAL TO IMPROVE THE WRITING SKILLS OF EFL STUDENTS
Authors: Fuat Keyman , Keithman John
Published: September 2020

This study investigates the use of authentic material to improve the EFL students’ writing skills. Data was collected during the academic year 2018–2019. Participants in the study (N = 365) were all enrolled in English writing courses and totaled 200 male students and 165 female students. The results of ANOVA (analysis of variance) tests showed that female students have higher scores than male students, and Social Science students have higher scores than Non-Social Science students. In response to these findings, a program for direct strategy instruction was piloted with an English writing class at one of the sample universities. Encouraging results from this trial program suggest new avenues for approaching the teaching of writing.Keywords: Authentic material, English as a Foreign Language (EFL), Writing Skill.
Releasing Dependency on Western Culture in Efforts to Contextualize Christian Theology and Education in Asia
Authors: Sanjaya Yudhy , Butar Rikardo Butar , Waruwu Septerianus
Published: September 2020

Contextualization in theology is an interesting thing to observe because the development of theology cannot be separated from culture. And nowadays western thoughts greatly influence theology in the world, including in Asia. This is due to the large number of theologians from parts of the western world who pour their main thoughts in books that are made into literature by theologians today in theology and in the world of Christian education. This paper tries to look from a different perspective where Christian theology and education should be based on the culture that has developed in Asian society. It is hoped that the ideas of local theologians will emerge who have influenced the development of theology in Asia. Through the method of studying literature from Asian theologians and observing the phenomena that occur, the writer tries to give the idea that in doing theology and developing Christian education it is necessary to explore Asian local wisdom and release the dependence on Western theology
Some thought on Shiller’s narrative economics
Authors: Ho Tung Manh
Published: September 2020

The Nobel Prize-winning economist Robert Shiller published an article in the American Economic Review in 20171 and a book in 20192 , both carrying the term “narrative economics.”
The role of feedback in risk-sensitivity
Authors: Dan Ohad , Loewenstein Yonatan
Published: September 2020

Over the last century, myriad versions of the bandit task were used to study operant conditioning in humans and other animals. However, the overwhelming majority of these variations utilized one of two types of feedbacks, partial and full feedback, revealing to participants the single outcome of the chosen alternative or the outcomes of all alternatives respectively. While ecologically relevant, when restricting the feedback method to these two methods alone, observed behavioral phenomena could potentially be confounded with specific effects that the feedback method itself might induce, for example attitude towards risk. Here we introduce a new form of feedback. In a 2-armed bandit task, the reverse feedback reveals to participants only the outcome of the unchosen alternative. In a behavioral experiment, human participants were incentivized to maximize their per-trial reward while exploring the reward-distribution associated with two alternatives. Randomly assigning participants to a specific type of feedback, we find that participants in the partial and reverse feedback condition demonstrated behavior consistent with risk aversion and risk seeking. This result is intriguing for two reasons. First, in gains-domain, humans are considered risk-averse and it is hence surprising to observe a robust demonstration of risk seeking. Second, We present risk-sensitivity as a casual outcome of the utilized feedback. Since in most ecological and lab environments humans utilize the partial feedback and demonstrate risk-aversion, our finding sheds new light on the common perception of risk-sensitivity as an inherent, rather than induced, characteristic. Utilizing a simple reinforcement learning model, we explain the emergent risk preference as an outcome of learning in the specific environment we use. We present the relation of our paradigm to prospect theory, relate our finding to existing literature, and discuss the new light our novel feedback-mechanisms shed on conclusions drawn from previous paradigms.
Relations between parent-child interaction and children’s engagement and learning at a museum exhibit about circuits
Authors: Sobel David , Letourneau Susan , Legare Cristine , Callanan Maureen
Published: September 2020

Play is critical for children’s learning, but there is significant disagreement over whether and how parents should guide children’s play. In an observational study of parent-child interaction and children’s learning, parents and 4- to 7-year-old children in the U.S. (N = 111 dyads) played together at an interactive electric circuit exhibit in a children’s museum. We examined how parents and children set and accomplished goals while playing with the exhibit. Children then participated in a set of challenges that involved completing increasingly difficult circuits. Children whose parents set goals for their interactions showed less engagement with the challenge task (choosing to attempt fewer challenges), and children whose parents were more active in completing the circuits while families played with the exhibit subsequently completed fewer challenges on their own. We discuss these results in light of broader findings on the role of parent-child interaction in museum settings.
Experiences, impacts and mental health functioning during a COVID-19 outbreak and lockdown: Data from a diverse New York City sample of college students
Authors: Lopez-Castro Teresa , Brandt Laura , Anthonipillai Nishanthi , Espinosa Adriana , Melara Robert
Published: September 2020

In March 2020, New York City (NYC) experienced an outbreak of coronavirus disease 2019 (COVID-19) which resulted in a 78-day mass confinement of all residents other than essential workers. The aims of the current study were to (1) document the breadth of COVID-19 experiences and their impacts on college students of a minority-serving academic institution in NYC; (2) explore associations between patterns of COVID-19 experiences and psychosocial functioning during the prolonged lockdown, and (3) explore sex and racial/ethnic differences in COVID-19-related experiences and mental health correlates. A total of 909 ethnically and racially diverse students completed an online survey in May 2020. Findings highlight significant impediments to multiple areas of students’ daily life during this period (i.e., home life, work life, social environment, and emotional and physical health) and a vast majority reported heightened symptoms of depression and generalized anxiety. These life disruptions were significantly related to poorer mental health. Moreover, those who reported the loss of a close friend or loved one from COVID-19 (17%) experienced significantly more psychological distress than counterparts with other types of infection-related histories. Nonetheless, the majority (96%) reported at least one positive experience since the pandemic began. Our findings add to a growing understanding of COVID-19 impacts on psychological health and contribute the important perspective of the North American epicenter of the pandemic during the time frame of this investigation. We discuss how the results may inform best practices to support students’ well-being and serve as a benchmark for future studies of US student populations facing COVID-19 and its aftermath.
Multispecies Sustainability
Authors: Rupprecht Christoph David Dietfried , Vervoort Joost , Berthelsen Christ , Mangnus Astrid , Osborne Natalie , Thompson Kyle , Urushima Andrea Flores , Kóvskaya Maya , Spiegelberg Maximilian , Cristiano Silvio , Springett Jay , Marschuetz Benedikt , Flies Emily , McGreevy Steven , Droz Laÿna , Breed Martin , Gan Jingchao , Shinkai Rika , Kawai Ayako
Published: September 2020

The sustainability concept in its current form suffers from reductionism. The common interpretation of “meeting the needs of the present without compromising the ability of future generations to meet their own needs” fails to explicitly recognize their interdependence with needs of current and future non-human generations. Here we argue that the focus of sustainability on human well-being – a purely utilitarian view of nature as a resource for humanity – limits its conceptual and analytical power, as well as real-world sustainability transformation efforts. We propose a broadened concept of ‘multispecies sustainability’ by acknowledging interdependent needs of multiple species’ current and future generations. We develop the concept in three steps: 1) discussing normative aspects, fundamental principles underlying the concept, and potential visual models, 2) showcasing radically diverging futures emerging from a scenario thought experiment based on the axes sustainable-unsustainable and multispecies-anthropocentric, and 3) exploring how multispecies sustainability can be applied to research and policy-making through two case studies (a multispecies stakeholder framework and the Healthy Urban Microbiome Initiative).
Evaluation of Efficacy of Various Implants in Maxillary Arch Distalization - A Finite Element Analysis
Authors: Sanap Sneha , Swami Vinit , Patil Amol , Deshmukh Shailesh , Bhosale Veera
Published: September 2020

Introduction: Orthodontic correction of Angle’s class II molar relation has, for long, been one of the challenges in orthodontics, with various researchers attempting to correct the class II molar relationship by diverse methods. One of the techniques that has gained popularity in recent times is maxillary arch distalization by infrazygomatic screws and miniscrews. The objective of the study is to measure and compare the amount of maxillary arch distalization and its effects, on adjacent teeth, by varying the positions of mini-implants by Finite Element Analysis.

Materials & Method: A standard three-dimensional finite element model was constructed to simulate the maxillary teeth, periodontal ligament, and alveolar process. In this study, three models were prepared. Model-1: The (miniscrews) were placed between upper first and second premolar, and between second premolar and first molar bilaterally. Model-2: Infrazygomatic screws was placed between upper first and second molar bilaterally. Model-3: Infrazygomatic screws was placed on the mesio-buccal root of upper first molar bilaterally. The displacement of each tooth was calculated on x, y, and z axes when 200 gm of force was applied on each side.

Result: Maximum amount of maxillary arch distalization was seen when infrazygomatic screws placed between upper first and second molar in model-2. Whereas maximum amount of maxillary arch intrusion and less distalization was observed when miniscrews placed between upper first premolar and second premolar and in between second premolar and upper first molar in model-1. The difference was statistically significant (p=0.005*). There was no bucco-palatal rotation of teeth observed among all three finite element models.

Conclusion: Thus infrazygomatic screws and miniscrews are the effective means of maxillary arch distalization for the correction of Class II malocclusion.
ІНФОРМАЦІЙНІ РИЗИКИ БЕЗПЕКИ ДИТИНИ У ТУРБУЛЕНТНОМУ ІНФОРМАЦІЙНОМУ СЕРЕДОВИЩІ З ПОЗИЦІЇ ДЕРЖАВНОГО УПРАВЛІННЯ
Authors: Panchenko Oleg
Published: September 2020

The transition to an informational lifestyle significantly increases the creative potential of society as a whole, and the individual in particular. Along with this, there is a significant increase of the load on the human’s mind under conditions of increasing flows of information and its turbulence. The information environment essentially becomes the main source of information for a person, has a direct impact on his mental activity, on the formation of his social behavior. A person is forced to live in this environment, to perceive its realities adequately, to adapt to information threats from this environment. The awareness of these threats has led to careful attention to information security. A child, being a specific member of a society, nevertheless acts as a full-fledged participant in information relations, and must be in such a state of protection, in which there is no risk associated with information causing harm to his health, physical, mental, spiritual and moral development.A child in his development, processing information, actively assimilates social experience, as well as a system of social connections and relationships, and subsequently reproduces all this in his life. In the course of this process, he acquires the qualities, values, beliefs and forms of behavior that he needs for normal life.Ensuring the information security of a child implies protection because of the destabilizing effect of information on health and mental, spiritual and moral development; creation of conditions for the information environment for positive socialization and individualization of the personality, optimal social, personal, cognitive and physical development, preservation of somatic, mental and psychological health and well-being, the formation of a positive worldview. The latter is possible when determining the main directions of state policy in the interests of children and the key mechanisms for its implementation, based on the generally recognized principles and norms of the international law.
Physical Therapy for Neurodegenerative Diseases: An Educational Approach
Authors: Chakraborty Ashok , Chakraborty Ashok , Chakraborty Ayan , Smith Kylie , Chakraborty Debjit , Guha Smita
Published: September 2020

The most progressive neurodegenerative disease so far we know are Alzheimer’s disease (AD) and
Parkinson’s disease (PD). They manifest cognitive and motor disorders, respectively. No cures are found
yet for both the diseases, except some palliatives. At this stage, some alternative measures can be adopted
that may slowdown the further progression and may bring comfort to the affected people. Epidemiological
data supports a direct relationship between the physical activity (PA) and the risk of developing those two
diseases. Aerobic physical exercise (PE) induces the release of neurotrophic factors, promotes angiogenesis,
neurogenesis and synaptogenesis, and improves memory and cognitive functions. Further, PE activates the
superoxide scavengers, like superoxide dismutase, endothelial nitric oxide synthase, and thereby protects
the hippocampus, which is involved particularly in memory function. AD and PD not only deteriorate the
quality of life but also may cause death. Therefore, any positive impact of non-pharmacological
interventions, such as physical activity and exercise, would improve public health.
STUDY OF THE PROLONGING EFFECT DUE TO THE INTERACTION OF POLYCOMPLEX COMPOSITES WITH MEDICINAL SUBSTANCES
Authors: Inagamov S.Ya , Shadmanov K.K. , Muhamedov G.I.
Published: September 2020

The nature of the formation of polycomplexes and polycomplex composites was investigated by IR spectroscopy, and the kinetics of the release of drugs from the base were studied by the pharmacokinetic method. Experimental data obtained under “in vitro” conditions showed a prolonging effect in comparison with the initial polymers (Na – CMC) and hydrophobic petrolatum (control), which can be explained by the interaction of drugs with polycomplexes and polycomplex composites. It was found that a high prolonging effect of drugs due to their slow release from the base layers of polycomplex composites.
INVESTIGATION OF LEAKAGE CURRENT DISTRIBUTION IN ELECTRICAL WIRING THAT FEEDS A GROUP OF ELECTRIC RECEIVERS WITH A MOTOR LOAD
Authors: Balashov O. P.
Published: September 2020

The article investigates the distribution of leakage current in low voltage wiring. The regression equation is obtained, which makes it possible to accurately predict the value of the leakage current of the electrical wiring supplying a group of power receivers with motor load.
ON THE THEORY OF THE ORIGIN OF GLOBAL CLUSTER SYSTEMS AROUND THE GALAXIES
Authors: Tadzhibaev I.U. K
Published: September 2020

The origin of poor and moderate globular cluster systems around galaxies against the background of a nonlinear non-stationary model of collapsing galaxies is studied. The stability of the model with respect to four perturbation modes is studied, and the degree of the mode determines on average the number of clusters in the system. A critical dependence of the initial virial relation on the degree of rotation is constructed for each mode. The dependences of the instability increments on the physical parameters of the model are found.
FORMATION OF INTENSIVE BEAMS OF CHARGED PARTICLES IN A TRANSAXIAL CATHODE LENS
Authors: Ibrayev A.T.
Published: September 2020

The paper proposes a method for taking into account the effect of space charge on the quality of focusing of charged particles and investigates the problem of the formation of an intense flux of charged particles using a transaxial cathode lens, which is a special case of cathode lenses with two planes of symmetry. The article solves a self-consistent problem by representing the distribution functions of potentials and space charge in the form of power series in small parameters. The author uses an improved and proven method for studying cathode lenses, based on taking into account the longitudinal component of the total aberration. The necessary equations and formulas are obtained for calculating the parameters and designing a source of charged particles based on a transaxial cathode lens.
CHIMERIC NOVELTY OF THE OBTAINED RESULTS RESEARCH ABOUT MVL AIRPORTS
Authors: Leontyev R.G.
Published: September 2020

The article considers the absurd attempt of its producers presented in the review of the leading organization to reveal the chimeric novelty of the results, conclusions and recommendations of the dissertation on the management of local airlines. It is proved that this attempt of MIIT employees was caused by their negligent ignorance of the text of the dissertation, and its (attempts) resulted in a falsified (that is, in fact, non-existent in reality) content of this scientific qualification work.
THE OPPONENT'S ATTEMPTS TO SCREAM PERSONAL CONTRIBUTION AND THE
IMPORTANCE OF RESEARCH ABOUT MVL AIRPORTS
Authors: Leontyev R.G.
Published: September 2020

The article analyzes the assessments of the applicant's personal contribution and the practical significance of the study of the management of local airlines, presented in the review of the official opponent (professor). It has been proven that these assessments are not only falsified, but generally inappropriate information intended to give this review the appearance of a highly qualified document of state scientific certification and thereby confuse the entire expert community and other members of the scientific community about the relevance of the dissertation considered by the opponent.
TᡃHE DIGᡃITAL FUTᡃURE OF RUSᡃSIAN SUBᡃSEA OIL & GAS PRODUᡃCTION
Authors: Harlanov A.S. , Eremicheva T.V. , Storozheva A.E.
Published: September 2020

The possibᡃilities and abiᡃlity of the Rusᡃsian Stᡃate and socᡃiety to partiᡃcipate in gloᡃbal develᡃopment boᡃth in genᡃeral and in partiᡃcular, by stabiᡃlizing the moᡃst impoᡃrtant secᡃtors of the ecoᡃnomy and socᡃial secᡃtors of thᡃeir couᡃntry by introᡃducing the latᡃest digᡃital technoᡃlogies and digitalᡃization all arᡃeas of develoᡃpment, are examᡃined. The quesᡃtion remᡃains opᡃen: the measᡃures appᡃlied are the onᡃly onᡃes neceᡃssary to maᡃke a breaktᡃhrough the induᡃstry or are thᡃey reaᡃlly objeᡃctive at the tiᡃme of gloᡃbal transfoᡃrmation?
Violences intentionnelles, manifestations somatiques et traumas complexes chez les réfugiés et demandeurs d’asile
Authors: Chahraoui K.
Published: September 2020

Les populations de réfugiés, déplacés, demandeurs d’asile qui ont été soumises à des conflits armés, guerres, violences organisées présentent une grande souffrance psychique qui peut se traduire par de nombreux problèmes de santé mentale (états de stress post-traumatiques, dépressions, deuils compliqués, troubles somatiques, troubles dissociatifs). La place des manifestations somatiques (douleurs chroniques, plaintes et troubles somatiques divers) a été peu traitée pour cette population. L’objectif de cet article est de souligner leur importance et leur lien avec le vécu des traumas extrêmes et intentionnels. Quelques données de la littérature sont présentées pour illustrer les fortes corrélations entre les violences collectives, les troubles de stress posttraumatique et les problèmes somatiques. L’accent est ensuite mis sur un essai de compréhension des vulnérabilités liées à ces traumas complexes où la composante somatique est toujours présente. Sont analysés en particulier les effets et les processus psychotraumatiques spécifiques des violences intentionnelles : la déshumanisation, le clivage, la dissociation psychique, les vécus de honte, de culpabilité et la mémoire traumatique corporelle. Nous terminons par quelques pistes thérapeutiques tenant compte des problématiques à la fois corporelles et culturelles de ces patients.
Diagnostic, pronostic et prise en charge de l’infection congénitale à cytomégalovirus (CMV) pendant la grossesse
Authors: Faure-Bardon V. , Leruez-Ville M. , Ville Y.
Published: September 2020

L’infection à cytomégalovirus est bénigne pour la femme enceinte, mais en cas de transmission verticale, les conséquences fœtales peuvent être désastreuses. Les diagnostics de primo-infection maternelle et d’infection fœtale sont réalisables par des tests performants et accessibles. Le pronostic est principalement conditionné par le trimestre de contamination fœtal et l’imagerie prénatale. Le traitement par valaciclovir est efficace à la fois pour réduire le risque de transmission verticale mais aussi pour réduire le risque de séquelles. L’ensemble des données récentes concernant le diagnostic, le pronostic, et la prise en charge prénatale est ici abordée.
Language network reorganization before and after temporal lobe epilepsy surgery
Authors: Foesleitner Olivia , Sigl Benjamin , Schmidbauer Victor , Nenning Karl-Heinz , Pataraia Ekaterina , Bartha-Doering Lisa , Baumgartner Christoph , Pirker Susanne , Moser Doris , Schwarz Michelle , Hainfellner Johannes A. , Czech Thomas , Dorfer Christian , Langs Georg , Prayer Daniela , Bonelli Silvia , Kasprian Gregor
Published: September 2020

OBJECTIVE

Epilepsy surgery is the recommended treatment option for patients with drug-resistant temporal lobe epilepsy (TLE). This method offers a good chance of seizure freedom but carries a considerable risk of postoperative language impairment. The extremely variable neurocognitive profiles in surgical epilepsy patients cannot be fully explained by extent of resection, fiber integrity, or current task-based functional MRI (fMRI). In this study, the authors aimed to investigate pathology- and surgery-triggered language organization in TLE by using fMRI activation and network analysis as well as considering structural and neuropsychological measures.

METHODS

Twenty-eight patients with unilateral TLE (16 right, 12 left) underwent T1-weighted imaging, diffusion tensor imaging, and task-based language fMRI pre- and postoperatively (n = 15 anterior temporal lobectomy, n = 11 selective amygdalohippocampectomy, n = 2 focal resection). Twenty-two healthy subjects served as the control cohort. Functional connectivity, activation maps, and laterality indices for language dominance were analyzed from fMRI data. Postoperative fractional anisotropy values of 7 major tracts were calculated. Naming, semantic, and phonematic verbal fluency scores before and after surgery were correlated with imaging parameters.

RESULTS

fMRI network analysis revealed widespread, bihemispheric alterations in language architecture that were not captured by activation analysis. These network changes were found preoperatively and proceeded after surgery with characteristic patterns in the left and right TLEs. Ipsilesional fronto-temporal connectivity decreased in both left and right TLE. In left TLE specifically, preoperative atypical language dominance predicted better postoperative verbal fluency and naming function. In right TLE, left frontal language dominance correlated with good semantic verbal fluency before and after surgery, and left fronto-temporal language laterality predicted good naming outcome. Ongoing seizures after surgery (Engel classes ID–IV) were associated with naming deterioration irrespective of seizure side. Functional findings were not explained by the extent of resection or integrity of major white matter tracts.

CONCLUSIONS

Functional connectivity analysis contributes unique insight into bihemispheric remodeling processes of language networks after epilepsy surgery, with characteristic findings in left and right TLE. Presurgical contralateral language recruitment is associated with better postsurgical language outcome in left and right TLE.
A data-driven model to identify high-risk aneurysms and guide management decisions: the Rupture Resemblance Score
Authors: Rajabzadeh-Oghaz Hamidreza , Waqas Muhammad , Veeturi Sricharan S. , Vakharia Kunal , Tso Michael K. , Snyder Kenneth V. , Davies Jason M. , Siddiqui Adnan H. , Levy Elad I. , Meng Hui
Published: September 2020

OBJECTIVE

Previous studies have found that ruptured intracranial aneurysms (RIAs) have distinct morphological and hemodynamic characteristics, including higher size ratio and oscillatory shear index and lower wall shear stress. Unruptured intracranial aneurysms (UIAs) that possess similar characteristics to RIAs may be at a higher risk of rupture than those UIAs that do not. The authors previously developed the Rupture Resemblance Score (RRS), a data-driven computer model that can objectively gauge the similarity of UIAs to RIAs in terms of morphology and hemodynamics. The authors aimed to explore the clinical utility of RRS in guiding the management of UIAs, especially for challenging cases such as small UIAs.

METHODS

Between September 2018 and June 2019, the authors retrospectively collected consecutive challenging cases of incidentally identified UIAs that were discussed during their weekly multidisciplinary neurovascular conference. From patient 3D digital subtraction angiography, they reconstructed the aneurysm geometry and performed computer-assisted 3D morphology analysis and computational fluid dynamics simulation. They calculated RRS for every UIA case and compared it against the treatment decision made at the neurovascular conference as well as the recommendation based on the unruptured intracranial aneurysm treatment score (UIATS).

RESULTS

Forty-seven patients with 79 UIAs, 90% of which were < 7 mm in size, were included in this study. The mean RRS (range 0.0–1.0) was 0.24 ± 0.31. At the conferences, treatment was endorsed for 45 of the UIAs (57%). These cases had significantly higher RRSs than the 34 cases suggested for observation (0.33 ± 0.34 vs 0.11 ± 0.19, p < 0.001). The UIATS-based recommendations were “observation” for 24 UIAs (30%), “treatment” for 21 UIAs (27%), and “not definitive” for 34 UIAs (43%). These “not definitive” cases were stratified by RRS based on similarity to RIAs.

CONCLUSIONS

Although not a rupture predictor, RRS is a data-driven model that gauges the similarity of UIAs to RIAs in terms of morphology and hemodynamics. In cases in which the UIATS-based recommendation is not definitive, RRS provides additional stratification to assist the identification of high-risk UIAs. The current study highlights the clinical utility of RRS in a real-world setting as an adjunctive tool for the management of UIAs.
Procalcitonin in the context of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage
Authors: Veldeman Michael , Lepore Daniel , Höllig Anke , Clusmann Hans , Stoppe Christian , Schubert Gerrit Alexander , Albanna Walid
Published: September 2020

OBJECTIVE

Aneurysmal subarachnoid hemorrhage (aSAH) initiates a deleterious cascade activating multiple inflammatory processes, which can contribute to delayed cerebral ischemia (DCI). Procalcitonin (PCT) is an established marker for sepsis treatment monitoring, and its time course in the context of DCI after aSAH remains unclear. The aim of this trial was to assess the predictive and confirmative value of PCT levels in the context of DCI.

METHODS

All patients admitted to the authors’ institution with aSAH between 2014 and 2018 were prospectively screened for eligibility. Daily PCT levels were recorded alongside relevant aSAH characteristics. The predictive and confirmative values of PCT levels were assessed using a receiver operating characteristic and area under the curve (AUC) analysis. The course of PCT levels around the DCI event was evaluated in an infection-free subgroup of patients.

RESULTS

A total of 132 patients with aSAH were included. Early PCT levels (first 3 days post-aSAH) had a low predictive value for the development of DCI (AUC 0.661, standard error [SE] 0.050; p = 0.003) and unfavorable long-term outcome (i.e., Glasgow Outcome Scale–Extended scores 1–4; AUC 0.674, SE 0.054; p = 0.003). In a subgroup analysis of infection-free patients (n = 72), PCT levels were higher in patients developing DCI (p = 0.001) and DCI-related cerebral infarction (p = 0.002). PCT concentrations increased gradually after DCI and decreased with successful intervention. In refractory cases progressing to cerebral infarction, PCT levels showed a secondary increase.

CONCLUSIONS

Early higher PCT levels were associated with the later development of DCI and unfavorable outcome. Analysis of PCT beyond the first couple of days after hemorrhage is hampered by nosocomial infections. In infection-free patients, however, PCT levels rise during DCI and an additional increase develops in patients developing cerebral infarction.

Clinical trial registration no.: NCT02142166 (clinicaltrials.gov)