bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring the symptoms and psychological experiences among lung cancer convalescence patients after radical lobectomy: a qualitative study
Authors: Xiao Julan , peng Yueming , Li Yun , Ye Fengqing , Zeng Zhixong , Lin Xiaoxu , Xie Yanheng , Cheng Sijiao , Wen Yi , Luo Weixiang
Published: April 2023

Background In the convalescence period of patients after radical lung cancer surgery, the influence of symptoms and psychological experiences among lung cancer convalescent patients after radical lobectomyhas received little research attention.
Purpose This study aims to explore the symptom experiences and psychological feelings of lung cancer patients after radical lobectomy in China.
Methods A qualitative study was conducted using face-to-face semistructured interviews with lung cancer patients who had a radical lobectomy for treatment of their cancer during the convalescence period. Participants (n=18) were recruited from a general hospital in China, and patients were selected using purposive sampling from September 2021 to February 2022. Interviews were recorded and transcribed verbatim, and Colaizzi’s seven-step method of phenomenology was used. The Consolidated Criteria for Reporting Qualitative Research (COREQ) checklist was conducted to report the study.
Results Four themes were extracted from the interview data: physiological dimensions (fatigue, cough or sputum, chest tightness and shortness of breath, daily activities affected, sleep disturbance, lack of appetite); psychological dimensions (negative emotion, fear of cancer recurrence, learning to accept reality, strengthened faith and hope); family dimensions (heavy economic burden, perceived family care, improved health management behavior); and social dimensions (perceived support of medical staff, decreased sense of social value and self-identity, changes in social and working style).
Conclusion Lung cancer patients are still troubled by many problems during the postoperative recovery period. Medical staff should design and implement effective evaluations and targeted interventions for patients’ physical and mental health as soon as possible to improve patients’ physical and mental health, as well as their quality of life.
SYT2/11/13/15 Are Potential Prognostic Biomarkers and Correlate to Immune Infiltration in Lung Adenocarcinoma
Authors: Wang Yu-Sheng , Zhou Chao , Zhang Zheng-Wei , Shi Xiao-Qian , Zhao Xue-Wei , Liu Yang , Li Bing , Yang Meng-Hang
Published: April 2023

Background Lung adenocarcinoma (LUAD) is one of the most prevalent and lethal malignancies worldwide. Synaptotagmins (SYTs) are a group of transmembrane proteins of which dysregulation has been reported in various cancers. Here, we analyzed the role of SYT2/11/13/15 in LUAD using bioinformatic methods.Methods In TCGA-LUAD cohort, we compared the expression level of SYTs in LUAD and normal tissue. To determine their biological functions, protein-protein interaction (PPI) network was constructed and GO/KEGG analysis were performed. GSEA were used to find the pathway changes. DNA methylation changes in SYT2/11/13/15 were investigated based on MethSurv. The impact on immune cell infiltration were revealed using TIMER database. The diagnostic power of SYT2/11/13/15 were studied using Kaplan-Meier plotter, diagnostic receiver operating characteristic (ROC) curves, nomogram model, and Cox regression analysis.Results In brief, we found that SYT2/13 were upregulated and SYT11/15 were down-regulated in LUAD, high expression of SYT2/11/15 predicted a favorable prognosis while SYT13 indicated a poor one. Functional analysis showed that SYTs mainly involved in neuroactive signal transduction. Several CpG islands of SYTs genes correlated to poor prognosis were identified. Cox regression analysis showed that SYT2/11/13/15 are independent risk factors for overall survival (OS) and disease-specific survival (DSS) of LUAD patients. SYT11/15 were closely related to immune infiltration in LUAD, SYT11 correlated to CD8 + T cell, dendrite cell (DC), macrophages. SYT15 correlated to CD4 + T cell, DC, and myoid derived suppressor cell (MDSC).Conclusion To sum up, we found that SYT2/11/13/15 were differentially expressed and were potential prognostic biomarkers, and may modulate immune infiltration in LUAD.
Anxiety, Knowledge, Misconceptions, Behavioral Intentions and Prevention Practices in COVID-19 First Year of Pandemic: Network or Psychometric Model?
Authors: Bastos Rafael Valdece Sousa , Ansah Edward Wilson , Sarfo Jacob Owusu , Marsura Amanda Costa , Aquino Sibele Dias , Melo Cynthia Freitas , Lins Samuel Lincoln Bezerra
Published: April 2023

The SARS-CoV-2 pandemic has spread rapidly worldwide, being life-changing and affecting anxiety, misconceptions, knowledge, and people's health behavioral intentions, which is related to COVID-19 prevention practices adherence. Thus, it is relevant to test whether related measures would have a factor or network model in different populations, and know its’ relations as complex systems. The goal of this research is to test whether the Fear and Health-Seeking Behavioral Intentions Scales follow a network or factor model in a Brazilian sample, in addition to an attempt to understand COVID-19 psychological impacts and its relations in a Brazilian sample during the first year of the pandemic. To do so, we used recent developments in the field of network and psychometrics, with a sample of 476 Brazilians collected during the first pandemic year. We found evidence for a network model using two approaches. In addition, we used the network model to see the relationship between those variables, and the findings are discussed. We highlighted the importance of COVID-19 knowledge, misinformation, and prevention practices adherence relation in the network structure.
Peripheral blood CD3+HLADR+ cells and associated gut microbiome species predict response and overall survival to immune checkpoint blockade
Authors: Gorgulho Joao , Roderburg Christoph , Beier Fabian , Bokemeyer Carsten , Brümmendorf Tim H. , Luedde Tom , Loosen Sven H.
Published: April 2023

Background The search for biomarkers to identify ideal candidates for immune checkpoint inhibitor (ICI) therapy is fundamental. In this study, we analyze peripheral blood CD3 + HLADR + cells (activated T-cells) as a novel biomarker for ICI therapy and how its association to certain gut microbiome species can indicate individual treatment outcomes.Methods Flow cytometry analysis of peripheral mononuclear blood cells (PBMCs) was performed on n = 70 patients undergoing ICI therapy for solid malignancies to quantify HLA-DR on circulating CD3 + cells. 16s-rRNA sequencing of stool samples was performed on n = 37 patients to assess relative abundance of gut microbiota.Results Patients with a higher frequency of CD3 + HLADR + cells before treatment initiation showed a significantly reduced tumor response and overall survival (OS) and experienced less toxicities to ICI therapy. As such, patients with a frequency of CD3 + HLADR + cells above an ideal cut-off value of 18.55% had a median OS of only 132 days compared to 569 days for patients below. Patients with increasing CD3 + HLADR + cell counts during therapy had a significantly improved OS. An immune signature score comprising CD3 + HLADR + cells and the neutrophil-lymphocyte ratio (NLR) was highly significant for predicting OS before and during therapy. When allied to the relative abundance of microbiota from the Burkholderiales order and the species Bacteroides vulgatus, two immune-microbial scores revealed a promising predictive and prognostic power.Conclusion We identify the frequencies and dynamics of CD3 + HLADR + cells as an easily accessible prognostic marker to predict outcome to ICIs, and how these could be associated with immune modulating microbiome species. Two unprecedented immune-microbial scores comprising CD3 + HLADR+, NLR and relative abundance of gut bacteria from the Burkhorderiales order or Bacteroides vulgatus species could accurately predict OS to immune checkpoint blockade.
Icariin Mediates Reactive Astrocytes after Spinal Cord Injury via YAP and TGF-beta Signaling.
Authors: zhou mengmeng , Ma Boyuan , Fu Xuanhao , Cheng Yuelin , Liu Linyan , Kan Shunli , Liu Chengjiang , Zhao Xinyan , Sa Feng , Jiang Zehua , Zhu Rusen
Published: April 2023

Icariin (ICA) is the main active component of the traditional Chinese medicine Epimedium, which has been confirmed to play a neuroprotective role in spinal cord injury (SCI) models. Astrocyte activation is a key link in “inflammatory storms” after SCI, and eventually form glial scar to inhibit neurological recovery. Studies have shown that icariin can effectively inhibit inflammatory response and promote the recovery of nerve function after SCI, but the specific mechanism is still unclear. This study applied network pharmacology and in vivo experimental verification to explore the molecular mechanism of ICA in the treatment of SCI. A total of 37 targets were screened out, mainly enriched in response to hypoxia, response to abiotic stimulus, regulation of cellular response to stress, and the TGF-beta signaling pathway etc. In the animal experiments, the Basso, Beattie and Bresnahan scores and Hematoxylin Eosin staining revealed that ICA could effectively improve the behavioral and histological recovery of SCI rats. Then ICA was confirmed to reduce astrocyte GFAP, Vimentin, and the expression of Ki-67 after SCI. Furthermore, ICA could inhibit the TGF-beta signaling pathway. ICA could also inhibit the expression of Yap protein. However, when Yap protein was activated, ICA inhibited the TGF-beta signaling pathway and reactive astrocyte activation was reversed. To sum up, the mechanism of ICA treatment for SCI may involve the inhibition of reactive astrocyte activation by inhibiting the expression of Yap protein and down-regulating the TGF-beta signaling pathway.
Performance Comparisons of Content-Based Video Search Engine Retrieval Using Different Similarity Algorithms
Authors: Adly Ahmad Sedky , Hegazy Islam , Elarif Taha , Abdelwahab M. S.
Published: April 2023

Content-based video search engines (CBVSE) are broadly needed in many mainstream video search engines retrieving videos from public video streaming services over the Internet such as YouTube. As they are mostly text-based search engines that index and retrieve videos depending on the surrounding text around the video web page that contains information representing this video file. This paper is an attempt to improve the performance of a previously developed technique for a content-based video search engine designed to firstly index videos on YouTube and search and retrieve videos using a non-semantic video query. Moreover, a large-scale dataset was indexed containing more than 1088 YouTube video records. Each record contains a feature vector of the temporal set, key-objects sets, and keyframes representing video shots in each video file in addition to the URLs and other information gathered from each video file web page.
“You Are What You Eat”: Stereotype – Based Judgments of Ethnics on the Cuisines Which People Consume in Indonesia
Authors: Suroyo  , Putra Bima Maulana
Published: April 2023

The increased risk of prejudice in ethnic stereotypes against individuals based on the cuisine Individuals consume in Indonesia. The stereotype-based judgment of ethnic could examine the character traits included in the racially prejudiced issues against the ethnicity and discrimination of ethnics in Indonesia. The research objective in this study related to stereotype-based judgment with the concept of ethnic identity, with focus of the research is in the form of individual stereotypes-based judgment against other individuals based on the food consumed. This study is qualitative method involving ten participants from various ethnic groups in Indonesia. Moreover, the research questions in this research how stereotypes can affect an individual's ethnic identity with bringing discrimination of ethnics and minorities in Indonesia. The results found that people give a judgments of ethnics which could related to discrimination of ethnics in Indonesia, such as Sumatran Ethnic groups, Javanese roots, and eastern ethnics group which is similar to Polynesian communities. Even thought, the discrimination and stereotype-based judgment of ethnics on various local cuisines, individuals more pretend to understand and predict the ethnics of people consuming certain food from local area which brings negative perception of its ethnics.
A New Equation for Estimating Low-density Lipoprotein Cholesterol Concentration Based on Machine Learning
Authors: Chen Lei , Chen Rong , Ma Peidu , Li Yangyi , Deng Xue , Hua Muxing
Published: April 2023

Background Low-density lipoprotein cholesterol (LDL-C) is a crucial marker of cardiovascular system damage. In the Chinese population, the estimation of LDL-C concentration by Friedewald, Martin-Hopkins or Sampson equations is not accurate. Objective: The aim of this study was to develop a group of new equations for calculating LDL-C concentration using machine learning techniques and to evaluate their efficacy. Methods: A total of 182,901 patient samples were collected with standard lipid panel measurements. These samples were collated and randomly divided into a training set and a test set. In the training set, a new equation was constructed using polynomial ridge-regression and compared to the Friedewald, Martin, or Sampson equations in the test set. Subsequently, an additional set of 17,285 patient samples were collected to evaluate the performance of the new equation in clinical practice. Results: The new equation, a ternary cubic equation, was accurate and easy to use, with a goodness-of-fit R2 of 0.9815 and an uncertainty MSE of 37.4250 on the testing set. The difference between the calculated value by the new equation and the measured value of LDL-C was small (0.0424 ± 5.1161 vs Friedewald equation: -13.3647 ± 17.9198, vs Martin equation: -6.2969 ± 8.1036, vs Sampson equation: -8.9252 ± 12.6522, P < 0.001). It could accurately calculate LDL-C concentration even at high TG and low LDL-C. Furthermore, the new equation could also precisely calculate LDL-C concentration in actual clinical use (R2 = 0.9780, MSE = 24.8482).Conclusion: The new equation developed in this study can accurately calculate LDL-C concentration within the full concentration range of TG and LDL-C, and can serve as a supplement to the direct determination of LDL-C concentration for the prevention, treatment, evaluation, and monitoring of atherosclerotic diseases, compared to the Friedewald, Martin, or Sampson equations.
Synthesis and Characterization of Graphene Oxide (GO) Obtained by Modified Hummer’s Method: Application to the Removal of Cadmium ions from Wastewater
Authors: Hanane Ziani , Mhamed Kaid , Dlamila Ikhou , Mourad Makhlouf , Villemin Didier
Published: April 2023

Through its outstanding mechanical, electrical, and chemical properties, graphene oxide has been regarded as a significant material since its discovery. This paper explains how to make graphene oxide (GO) using the Modified Hummer's method from pure graphite powder, which is the most prevalent approach. Multiple methods are been used to validate the physicochemical qualities and examine the morphological and structural aspects of the nano-composite sample, including Brunauer Emmett Teller, Fourier transform infrared spectroscopy, X-ray diffraction, and the scanning electron microscope (SEM). The objective of this study is to describe results from GO-based cadmium removal in aqueous solutions, followed by UV/VIS spectroscopy with xylenol orange indicator and a buffer solution pH=5, 8.
Various parameters (contact time , pH, amount of support, initial concentration, temperature, ionic strength, pHpzc) were investigated in detail and the maximum adsorption capacity of the metal ion adsorbed by graphene oxide is 125 mg.g-1 .The Langmuir adsorption isotherm (R2≈0, 93) is found to suit the data better than the Freundlich and Temkin isotherms. Additionally, the kinetics of sorption are investigated using pseudo-first-order, pseudo-second-order, and Elovich models; the pseudo second order has been found to be the most suited to reflect the kinetic model (R2≈0, 99), and the thermodynamic parameters (ΔG°, ΔH° and ΔS°) are examined. The adsorption process is spontaneous and exothermic in character, as well as physical. Desorption characteristics and reusability of the produced material, on the other hand, are put to the test in five adsorption-desorption cycles.
Dominance and identity of the dominant bee drive bee diversity on flowers
Authors: Varma Sangeetha , Rajesh T. P. , Manoj K. , Asha G. , Jobiraj T. , Sinu Palatty Allesh
Published: April 2023

Communities are characterized by the dominance of a few species, which are crucial for shaping communities. Bees compete for scarce resources, and offer an ideal system to study the effect of dominance on the diversity of bees. The effect of bee dominance is studied predominantly for the western honeybee, which can have negative effects in introduced sites. Solitary bees, stingless bees, native honeybees, and bumblebees can also be dominant on flowers. We test the hypothesis that dominance, regardless of the identity of the species, negatively influence diversity of bees on flowers. We analyzed 95,160 visits of 58 species of bees belonging to honeybees, solitary bees, and stingless bees on 59,211 flowers of 12 plant species across five years. Visitors were grouped into honeybees, solitary bees, and stingless bees. Proportion of the total abundance accounted by the most abundant species was considered as the estimate of dominance. Dominance negatively associated with richness and visitation rate of bees, but identity of bee functional group predicted the magnitude of the effects. Richness decreased with the dominance of honeybees and solitary bees, but not with the stingless bees. Visits of honeybees decreased when solitary bees dominated the visits. Visits of solitary bees decreased when honeybees or stingless bees dominated the flowers. We have shown that native bees of different functional groups can exert a similar negative effect on bee diversity in flowers like the invasive species do. Honeybees and stingless bees, though native in some parts, deteriorate bee diversity if augmented to ecosystems unnecessarily.
Synthesis, Antimicrobial Activity, and Drug-likeness profiles of 5-Phenylselenanyl-2-benzylthiopyrimidine Analogs
Authors: Jeelan
Published: April 2023

Given literature findings on the biological importance of pyrimidine and thiazolidine, we herein report synthesis and antimicrobial activity of 5-phenylselenanyl-2-benzylthio- pyrimidin-4-yl) thiazolidine-4-one analogs 4(a, b). Compound 5-phenylselenenyl-4-hydrazino-2-benzylthiopyrimidines (2) on condensation with substituted aromatic aldehydes afforded the corresponding Schiff bases 5-phenylselenenyl-4-(substituted benzylidenehydrazino)-2-benzylthiopyrimidine 3(a-c). Finally, the cyclization of compounds 3(a-c) with thioglycolic acid in benzene as solvent yielded target compounds 4(a, b). The structures of synthesized compounds were characterized by spectral studies such as IR, 1H-NMR, and Mass spectra. Results obtained by screening these synthesized compounds for antimicrobial activity reveal that only 1, 2, 3a, 3b, and 4a exhibited good antibacterial activity against P. aeruginosa compared to the standard drug gentamycin. Among all pyrimidine analogs, compound 4b has shown good antifungal activity against the fungal strain A. niger and A. terreus. Other compounds have shown moderate to poor antifungal activity when compared with fluconazole. Also, ADMET properties were studied for synthesized compounds.
ExoPSI: A Planet Similarity Python toolkit
Authors: Garg Vaibhav , Rai Aditya , Sriniva Divya , Rao A. S.
Published: April 2023

The Earth Similarity Index (ESI) has proven to be an essential tool in locating Earth-like planets throughout the universe, yet its limited scope restricts its full potential. ExoPSI is a groundbreaking, open-source Python package that elevates the concept of similarity indexing. It provides the capability to calculate similarity indices of different planetary candidates with respect to any reference values, based on any numerical parameter, yielding a more accurate evaluation of the survivability of different species. ExoPSI offers unparalleled versatility, with the ability to use any planet as a reference point and visualisation functions that allow for easy comparison of the similarity between the interior and surface parameters of different planets. This makes it a critical tool for planetary science researchers, offering a comprehensive solution for evaluating planetary similarities.
On a Class of Non-Univalent functions Associated with a Parabolic Region
Authors: Kumar S. Sivaprasad , Mundalia Mridula
Published: April 2023

In the present investigation, we introduce and study the geometric properties of a class of analytic functions, associated with a parabolic region majorly lying in the left-half plane. Further we establish radius and majorization results for the class under study with pictorial illustrations of some of its special cases. Also we derive some sufficient conditions for the class under consideration.
MSC Classification: 30C45 , 30C80
The Hubble Tension Produces New Physics
Authors: Baruch John
Published: April 2023

The Hubble constant measures the rate of expansion of the universe. Measurements of the Hubble constant, using the flash from the Big Bang, are in conflict with recent measurements using distant exploding stars. This conflict is referred to as the Hubble Tension. The exploding stars measurements also indicate that the rate of expansion of the universe is accelerating. The distance measurement tool is based on the brightness of Cepheid stars in our Milky Way galaxy. Recently, the Gaia satellite which measured the distance of these Cepheid stars from the Earth physically found that their measurements do not coincide with the brightness measurements made by other researchers. The conflict between the two distance measurements of these Cepheid stars has been reviewed (1), declared void and the Hubble tension maintained. Here we show the opposite:- that is, that a different approach to the same data decisively indicates that the Cepheid light is absorbed in the Milky Way. We know that a large amount of the mass of the Milky Way is of an unknown form called Dark Matter. Here we also show that the data of Freedman et al, (2), using stars in the Large Magellanic Cloud indicates strongly that dark matter is the absorber of the star light in both cases. We show that this Dark Matter absorption dismisses the Hubble Tension and the apparent acceleration in the expansion of the Universe. “New Physics” is proposed whereby the Stephen Hawking radiation from the extreme gravitational fields of Black Holes has an additional converse such that Dark Matter particles in the form of binaries absorb the light from the stars. It is shown that the mass of such particles is a billion times the mass of particles that the CERN hadron collider in Geneva can produce: about 2x1013GeV.
The effects of rehospitalization rate on transitional care using information communication technology in patients with heart failure: a scoping review
Authors: qikaixin  , Tomoko Koike , Youko Yasuda , Satoko Tayama , Itsumi Wati
Published: April 2023

Background: The number of people with heart failure is increasing. They have a high readmission rate and need ongoing health care and follow-up after hospital discharge. However, face-to-face nursing care is expensive; therefore, remote care options are required.
Objective: To reveal whether there are differences in effects (rehospitalization rate, and drug adherence) between face-to-face transitional care and remote technology, such as information and communication technologies, for transitional care in patients with heart failure within 30 days after discharge.
Design: Review
Setting: Patients with heart failure who received an information and communication technologies intervention within 30 days of discharge after being hospitalized for heart failure based on a review of published studies.
Methods: Eight English, Japanese, and Chinese databases were searched for research papers that examined outcomes such as readmission rates in patients with heart failure who received transitional care using remote technology. The search period was from 2000 to November 2021. This study was screened according to the PRISMA 2020 guidelines, and at least 17 papers were accepted.
Results: Seventeen studies were included in this review. In 14 studies, the readmission rates were lower in the transitional care group using information and communication technologies than in the control group, and the difference was statistically significant in ninestudies. In addition, one paper showed that the transitional care group improved patient satisfaction and quality of life more effectively.
Conclusions: Transitional care using information and communication technologies can provide necessary guidance according to the patient's timing, regardless of the patient's residence and time. Patients can send their self-monitored information to medical practitioners and receive timely feedback and guidance. With continuous follow-up support from the medical practitioner, the patient can adjust the plan to achieve a high degree of execution, and the patient's doubts and anxieties can be quickly resolved, increasing the patient's self-confidence. As a result, patients' self-care ability has improved, and it has become easier to control symptoms and prevent deterioration. We inferred that the transitional care group obtained a higher self-care ability than the control group. Transformational care using remote technologies such as information and communication technologies can help reduce readmission rates within 30 days after discharge compared to face-to-face care. In addition, the study showed that it may contribute to improving the quality of life and patient satisfaction.
Tweetable abstract: Information communication technology interventions after hospital discharge can decrease readmission rates in patients with heart failure.
Topological insulators and geometry of vector bundles
Authors: Sergeev Alexander S.
Published: April 2023

For a long time, band theory of solids has focused on the energy spectrum, or Hamiltonian eigenvalues. Recently, it was realized that the collection of eigenvectors also contains important physical information. The local geometry of eigenspaces determines the electric polarization, while their global twisting gives rise to the metallic surface states in topological insulators. These phenomena are central topics of the present notes. The shape of eigenspaces is also responsible for many intriguing physical analogies, which have their roots in the theory of vector bundles. We give an informal introduction to the geometry and topology of vector bundles and describe various physical models from this mathematical perspective.
Karakteristik Bubur Instan Berbasis Ubi Jalar Kuning sebagai Makanan Pendamping Air Susu Ibu (MP-ASI) untuk Pencegahan Stunting
Authors: Meisara Naura Delfi , Rialita Tita , Herminiati Ainia
Published: April 2023

This study aims to determine the proper pregelatinization time for producing an instant porridge of yellow sweet potato flour, which complied with SNI 01-7111.1-2005. The research method was a Randomized Block Design of three treatments pregelatinization time of 6, 8, 10 minutes with four replications. The selection treatment is determined by the best effectiveness index, which is the treatment of 10 minutes pregelatinization time resulted water adsorption capacity 2.47 g/mL, bulk density 0.49 mL, rehydration time 26.5 second, brew test 31.75 mL/g, 8.67% protein, 417.03 kcal total energy, 5.58 ɥg/g β-carotene (46.50 RAE/100 g), 2.64 % ash, 2.08 % moisture, 7.18% fat, 79.44 % carbohydrate, and 3.54 Log CFU/g TPC, has a sweet taste, high viscosity, soft texture, less bright color and a bit stronger aroma. This study concluded that yellow sweet potato-based instant porridge as complementary food can be one of nutrition-specific intervention aimed for stunting prevention. Penelitian ini bertujuan untuk menentukan waktu pragelatinisasi yang tepat untuk menghasilkan bubur instan berbahan baku tepung ubi jalar kuning yang sesuai SNI 01-7111.1-2005. Metode penelitian menggunakan Rancangan Acak Kelompok dengan tiga perlakuan waktu pragelatinisasi selama 6, 8, dan 10 menit, dengan masing-masing empat pengulangan. Pemilihan perlakuan ditentukan dari index efektivitas terbaik, yang dalam studi ini adalah bubur instan dengan waktu pragelatinisasi 10 menit dengan daya rehidrasi 2,47 g/mL, densitas kamba 0,49 mL, waktu rehidrasi 26,5 detik, dan uji seduh 31,75 mL/g, kadar protein 8,67 %, total energi 417,03 kkal, kadar β-karoten 5,58 ɥg/g (46,50 RAE/100 g), kadar abu 2,64 %, kadar air 2,08 %, kadar lemak 7,18 %, kadar karbohidrat 79,44 %, ALT 3,54 Log CFU/g, rasa manis, kekentalan tinggi, tekstur halus, warna agak tidak cerah, dan aroma yang agak kuat. Bubur instan berbasis ubi jalar kuning sebagai Makanan Pendamping Air Susu Ibu (MP-ASI) dapat menjadi salah satu bentuk intervensi gizi spesifik yang dapat dilakukan untuk pencegahan stunting.
Effect of Maternal Nutrition Education on Knowledge, Attitude, and Practice Related to Infant and Toddler Feeding
Authors: Majidah Nur Mukhlishoh , Sulistiyawati Sulistiyawati , Paramashanti Bunga Astria
Published: April 2023

This study aims to analyze the influence of maternal nutrition education on knowledge, attitude, and practice of infant and toddler feeding in a community feeding center in Sedayu Subdistrict, Bantul District, Yogyakarta. A quasi-experimental with pre- and posttest control group design was used in this study. Thirty-eight mothers were selected using total sampling in the community feeding center, which control group were chosen by matching the wasting status of their children. Mothers from intervention group were provided with nutrition education, while control group only received regular Posyandu(Pos pelayanan terpadu) programs. Mann-Whitney U test and Wilcoxon Signed Rank test were performed at a 5% level of significance. There was a significant improvement in mothers’ knowledge after receiving nutrition education. The difference elevation scores were shown between the intervention (85.25+14.67) and control (72.98+14.67) with p value=0.016; between pre-intervention (59.99+8.60) and post-intervention (85.25+14.67) groups (p0.001). However, maternal attitudes and practices related to infant and toddler feeding did not affect nutrition education. Maternal knowledge is the only outcome that is significantly affected by nutrition education.  Penelitian ini bertujuan untuk menganalisis pengaruh edukasi gizi pada ibu terhadap pengetahuan, sikap, dan praktik pemberian makan pada bayi dan anak di community feeding center di Kecamatan Sedayu, Kabupaten Bantul, Yogyakarta. Penelitian quasi-experimental ini menggunakan kelompok kontrol pre- dan posttest. Sebanyak 38 ibu dipilih menggunakan teknik total sampling di community feeding center dimana kontrol diambil dengan matching status wasting anak di posyandu. Ibu pada kelompok intervensi diberikan edukasi gizi sementara kontrol hanya menerima program regular di posyandu. Uji Mann-Whitney U dan Wilcoxon Signed Rank digunakan untuk analisis pada level signifikansi 5%. Terdapat perubahan signifikan pada pengetahuan ibu setelah mendapat edukasi gizi. Perbedaan peningkatan skor pengetahuan ditunjukkan di antara kelompok intervensi (85,25+14,67) dan kelompok kontrol (72,98+14,67) dengan p=0,016, dan di antara pre-intervensi (59,99+8,60) dan post-intervensi (85,25+14,67) dengan p0,001. Namun, tidak ada perubahan signifikan terkait sikap dan praktik pemberian makan pada bayi dan anak. Pengetahuan ibu merupakan satu-satunya outcome yang dipengaruhi oleh intervensi edukasi gizi.
Analisis Kandungan Gizi, Indeks Glikemik, dan Beban Glikemik Marshmallow Kulit Buah Naga dan Bayam Merah dengan Penambahan Stevia
Authors: Kurniawan Agung , Ilmi Ibnu Malkan Bakhrul , Fauziyah A'immatul
Published: April 2023

This study aims to determine the nutritional content, glycemic index, and glycemic load dragon fruit peel marshmallow and red spinach with the addition of stevia. This is an experimental syudy. The data collected in this study includes organoleptic data, nutrient content, glycemic index, and glycemic load. The analysis of nutritional content was carried out at the Saraswanti Indo Genetech (GIS) Laboratory in Bogor. Blood collection was done for glycemic index and glycemic load tests. The statistical analysis used to test the differences was the Kruskal Wallis test and continued with the Mann-Whitney test. The Kruskal Wallis test results showed that stevia sugar substitution had a significant effect (p 0.05) on the hedonic quality test and hedonic test. Formula 1 is the selected formula with 15% stevia sugar substitution. Formula 1 contains 35.25% water content, 1.66% ash content, 5.5% protein content, 0.67% fat content, and 57.45% carbohydrate content. The marshmallow glycemic index value of 87.29 is in the high category, while the glycemic load of 17.54 is in the moderate category. Dragonfruit peel marshmallow and red spinach with the addition of stevia are not yet appropriate for regular consumption by diabetics. Penelitian ini bertujuan untuk mengetahui kandungan gizi, indeks glikemik, dan beban glikemik marshmallow kulit buah naga dan bayam merah dengan penambahan stevia. Penelitian ini menggunakan desain eksperimental. Data yang dikumpulkan pada penelitian ini meliputi data organoleptik, kandungan zat gizi, indeks glikemik, dan beban glikemik. Analisis kandungan gizi pada penelitian ini dilakukan di Laboratorium Saraswanti Indo Genetech (SIG) Bogor. Pengambilan darah dilakukan untuk uji indeks glikemik dan beban glikemik. Analisis statistik yang digunakan untuk menguji perbedaan yaitu uji Kruskal Wallis dan dilanjutkan dengan uji Mann-Whitney. Hasil uji Kruskal Wallis menunjukkan substitusi gula stevia berpengaruh nyata (p 0,05) terhadap uji kualitas hedonik dan uji hedonik. Formula 1 adalah formula terpilih dengan substitusi 15% gula stevia. Formula 1 mengandung 35,25% kadar air, kadar abu 1,66%, kadar protein 5,5%, kadar lemak 0,67%, dan kadar karbohidrat 57,45%. Nilai indeks glikemik marshmallow sebesar 87,29 termasuk dalam kategori tinggi, sedangkan beban glikemik sebesar 17,54 termasuk dalam kategori sedang. Marshmallow kulit buah naga dan bayam merah dengan penambahan stevia belum tepat untuk dikonsumsi secara rutin oleh penderita diabetes.
Efektifitas Motion Graphic sebagai Media Pendidikan Gizi pada Karyawan di Masa Pandemi
Authors: Ismianti Ratna Dwi , Sitoayu Laras , Nuzrina Rachmanida , Wahyuni Yulia , Angkasa Dudung
Published: April 2023

The purpose of this study is to determine the effect of nutritional education through motion graphic media on knowledge and attitude of the four pillar of balanced nutrition in employees. The research is a quasy experimental study with two groups pretest-postest design. Sampling used was a purposive sampling. The target of this study is employees of Esa Unggul University who were divided into two groups, the intervention group that was given motion graphic and the control group which was not given the media, each group include 31 people. The results showed that there was an increase in knowledge in both the intervention group and the control group. Data analysis used was Mann-Whitney test. There was no difference in knowledge before intervention and there was a difference in knowledge after an intervention. As for the attitude, there was no difference in the two groups before, but there was a change in attitude in the intervention group. As the result, the study concluded that there is an effect of nutritional education with motion graphic media on the knowledge and attitude of the four pillars of balanced nutrition for Esa Unggul University’s employees.  Tujuan penelitian ini adalah untuk mengetahui pengaruh pendidikan gizi melalui media motion graphic terhadap pengetahuan dan sikap empat pilar gizi seimbang pada karyawan. Jenis penelitian ini eksperimental semu dengan two group pretest-postest design. Pengambilan sampel menggunakan teknik purposive sampling. Sampel merupakan karyawan Universitas Esa Unggul yang dibagi menjadi dua kelompok yaitu kelompok intervensi diberikan media motion graphic dan kelompok kontrol hanya diberikan ceramah. Masing-masing kelompok berjumlah 31 orang. Uji beda menggunakan uji Mann Whitney. Hasil penelitian menunjukkan ada peningkatan pengetahuan baik pada kelompok intervensi maupun kelompok kontrol. Tidak ada perbedaan pengetahuan sebelum intervensi antar kedua kelompok (p=0,189) dan ada perbedaan pengetahuan setelah intervensi antar kedua kelompok (p=0,001). Adapun untuk sikap, tidak ada perbedaan antar kedua kelompok sebelum (p=0,365) dan sesudah intervensi (p=0,435). Terdapat peningkatan sikap yang signifikan pada kelompok intervensi. Terdapat pengaruh pendidikan gizi dengan media motion graphic  terhadap pengetahuan dan sikap empat pilar gizi seimbang pada karyawan.
Ne Düşüneceğimizi Söyleyen Bir Üst Anlatı: Hayali Düzen
Authors: Akay Perihan
Published: April 2023

İnsanoğlu kalabalık toplumlar oluşturdukça, bu toplumları oluşturan bireyleri birbirine ve topluma bağlamak ve toplumsal yapının devam edebilmesini sağlamak için, hayali düzen adı verilen üst anlatılar geliştirmistir. Hayali düzen, imgeleri kullanarak, tarih boyunca insanın topluma ve kendisine bakışındaki pek çok şeyi belirlemiş, bireylerin hayali düzen ve önderle özdeşleşerek, ortak kimlikleriyle birbirlerine bağlanmasını sağlamıştır. Ancak hayali düzen, bireyin seçim ve uyum sağlama esnekliğini kısıtlar, çünkü herkese kendi mutluluk edinme ve acıdan korunma yolunu dayatır. Hayali düzenin temel yöntemi , yaşamın bireysel değerini düşürmek ve gerçek dünyanın tasarımını sanrılı bir biçimde değiştirirek kollektif düzeni yüceltmektir.
Hayali düzen ve bireysel özgürlük birlikte düşünüldüğünde, bireysel özgürlüğün, uygarlığın ya da hayali düzenin getirdiği bir şey olmadığı, uygarlığın ilerlemesinin, ancak hayali düzenin sorgulanmasi ve özgürlüğün adaletli biçimde dağıtılmasılmasi ile mümkün olacağı anlaşılmaktadır.
Bu sorgulama ve özgürlük talebi; bilimsel, sanatsal ve kültürel alanda da ortaya çıkacaktır. Sanatçı hayali düzen anlatılarıyla kendini sınırlamaksızın farkındalık yoluyala hayali düzeni sorgulayabilir.
Anxiety and perinatal depression in high-risk pregnancies at the fetomaternal polyclinic RSUP Prof. Dr. IGNG Ngoerah
Authors: Wardani Ida Aju Kusuma , Darmayasa I Made
Published: April 2023

Background: In this phase, a woman is prone to experiencing mental disorders due to an increase in psychological distress. There is some evidence that psychological stress during this period can have deleterious effects on the mother's health and may harm the child. The most common psychiatric disorders in the perinatal period are anxiety disorders and depression. Objective: To determine the prevalence of perinatal anxiety and depression in high-risk pregnancies. Method: The research sample was pregnant and postpartum women who checked themselves into the fetomaternal polyclinic at RSUP Prof. dr. IGNG Ngoerah as many as 41 people. The research was conducted by distributing the Beck Anxiety Inventory and Beck Depression Inventory questionnaires to the research sample. The research was conducted from October 1 2022 to October 31, 2022. Results: In this study, 7 people (17.1%) experienced mild anxiety and 11 people (26.8%) experienced moderate anxiety. For the prevalence of depression, 6 people (14.6%) had mild depression and 15 people (36.6%) had moderate depression. Perinatal anxiety and depression disorders are most commonly found in pregnant women with Human Immunodeficiency Virus (HIV) infection.
Релятивистские расчеты энергий низко возбужденных состояний 1sns, 1snp, 1snd и вероятностей однофотонных переходов 1snl -> 1sn'l' в гелиеподобном ионе урана
Authors: Дулаев Н.К. , Кайгородов М.Ю. , Малышев А.В. , Тупицын И.И. , Шабаев В.М.
Published: April 2023

For heliumlike uranium, the energies of the singly-excited 1sns, 1snp, and 1snd states with n ≤ 4 and the probabilities of the one-photon 1s3d -> 1s2p, 1s3p -> 1s2s, 1s3p -> 1s2p and 1s4d -> 1s2p transitions are evaluated. The calculations are performed within the Breit approximation using the configuration-interaction method in the basis of the Dirac-Fock-Sturm orbitals. The QED corrections to the energy levels are calculated employing the model-QED-operator approach. The nuclear recoil, frequency-dependent Breit-interaction, nuclear polarization, and nuclear deformation corrections are taken into account as well.
Изучение колебательных спектров и термического поведения фторидоцирконата натрия Na-=SUB=-5-=/SUB=-Zr-=SUB=-2-=/SUB=-F-=SUB=-13-=/SUB=-
Authors: Диденко Н.А. , Войт Е.И.
Published: April 2023

Методами дифференциального термического и термогравиметрического анализа (ДТА-ТГА), рентгенофазового анализа (РФА), колебательной спектроскопии исследованы строение и термическая устойчивость соединения Na5Zr2F13 на воздухе в интервале температур 20-800oС. Подтверждено наличие фазового перехода в высокотемпературную модификацию α-Na5Zr2F13 с динамически разупорядоченной структурой. Получены, систематизированы и обобщены данные инфракрасной спектроскопии (ИК), спектроскопии комбинационного рассеяния (КР) соединения β-Na5Zr2F13 и продуктов его разложения при нагревании. На основе результатов квантово-химических расчетов проведено отнесение полос в колебательных спектрах Na5Zr2F13. Ключевые слова: комплексные фториды циркония, фторидоцирконаты натрия, термогравиметрия, колебательная спектроскопия.
Нагрев слоя металла сканирующим лазерным пучком
Authors: Trofimov V. , Lin Pengcheng , Федоров С.В. , Розанов Н.Н. , Веретенов Н.А. , Wang Yan , Yang Yongqiang
Published: April 2023

The analysis and numerical simulation of the heating mode of a metal plate scanning beam of laser radiation was carried out. In the transverse-one-dimensional approximation, the estimates are obtained of the main dependences of the characteristics of the steady temperature profile on the parameters of the problem.
Investigating the Role of Upward Comparisons and Self-compassion on Stigma in People With Acne: Cross-sectional Study
Authors: Adkins Kate , Overton Paul G , Moses Julia , Thompson Andrew
Published: April 2023

Background

The use of image-laden social media is hypothesized as being implicated in psychological distress in individuals with conditions affecting their appearance. However, relatively little is known about the mechanisms involved in this relationship.

Objective

This cross-sectional study examined the relationship between photo-orientated social media use and feelings of stigmatization in adults with acne, and tested whether upward skin comparisons mediate and self-compassion moderates this relationship.

Methods

Adults (N=650) with acne symptoms completed web-based measures of social media use (daily Facebook or Instagram use, Facebook function use), self-compassion, skin appearance comparisons, and internalized stigmatization.

Results

Moderated-mediation and mediation analyses indicated that there was a significant indirect effect of Facebook photo use on stigmatization, mediated by upward appearance comparisons (estimation of indirect effect 11.03, SE 5.11, 95% CI 1.19-21.12). There was no significant relationship between Instagram use and feelings of stigmatization (estimation of indirect effect 0.0002, SE 0.005, 95% CI −0.011 to 0.009), yet upward appearance comparisons predicted feelings of stigmatization (B=0.99, P<.001). Self-compassion did not moderate the indirect or direct relationships between photo-orientated social media use and stigma. However, self-compassion was negatively correlated with upward appearance comparisons and feelings of stigmatization in both Facebook and Instagram users.

Conclusions

The way that individuals engage with social media, and in particular make appearance comparisons, should be considered when working with individuals with skin-related distress. Interventions aimed at boosting self-compassion and reducing appearance comparisons may provide avenues for protecting against feelings of stigma.
Results of unicondylar knee arthroplasty
Authors: Kalashnikov A.V. , Litun Y.M. , Stavinskyi Y.O.
Published: April 2023

Background. Partial knee replacement (PKR) becomes a more and more frequent method among the other methods of surgical treatment of early stages of medial knee osteoarthritis. The relevance and increasing number of PKR are confirmed by data from various national registers. The purpose of the research was to study the early functional results of PKR and to analyze the complications at various stages of the postoperative period. The assessment of the patient’s functional state according to the KSS and WOMAC was calculated as a percentage of the maximum possible sum of points for each of the scales. Material and methods. The results of 29 PKR during the period from 2016 to 2021 were analyzed. Assessment of knee function and quality of life of patients was performed according to the questionnaires Knee Scoring System (KSS), Western Ontario and McMaster Universities Arthritis Index (WOMAC), which were used preoperatively and then in 3, 6, 9, 12, 18 months after surgery. Results. The most significant improvement in quality of life and values of the functional results were observed in 3 and 18 months after surgery. After replacement it was established the best functional outcome scales of KSS (79.4%, p=0.03); WOMAC (27.1%, p = 0.02) compared with the functional results before surgery (32.3 and 73.6%, respectively). A negative correlation was revealed between body mass index and functional outcome (R = –0.7, p = 0.02). Conclusions. PKR allowed us to achieve an improvement in the quality of life and functional results already in the early postoperative period (from 3 to 18 months after the operation). The improvement of the operating technique and the analysis of errors will improve the results of PKR and minimize the number of complications.
A Sociolinguistics Analysis of Address Terms in Sasak Language
Authors: Rajabul Moh. Gufron
Published: April 2023

This research falls under the broad category of linguistics, i.e., sociolinguistics, which investigates the relationship between language and society. The objective of this research is to examine the sociolinguistic phenomenon known as "address terms" as performed by the native speakers of the Sasak language. This research employed a mix of descriptive, qualitative, and quantitative methods to describe a social phenomenon that occurs in the midst of society and is closely related to the address terms used by native Sasak speakers on Lombok Island. The data displayed in this research are the results of classified participatory and non-participatory observations, in-depth interviews, and online questionnaires. Based on the results of the findings and discussions, the researcher found several conditions. First, the address terms of native Sasak speakers are divided into eight patterns: 1. the nobility pattern; 2. the general pattern; 3. the intimacy pattern; 4. the borrowing pattern; 5. the kinship pattern; 6. the religious pattern; 7. the cultural pattern; and 8. the personal pronoun pattern. Secondly, the address terms serve the following functions: 1. to demonstrate intimacy; 2. to draw attention; 3. to demonstrate politeness; 4. to reflect identity; and 5. to demonstrate power differential. And last, the social factors affecting the use of address terms are: 1. social status; 2. age; 3. family relationship; 4. occupational hierarchy; and 5. degree of intimacy.