bluuebunny/crossref_metadata_2025 huggingface dataset:
Afrofem
Authors: De Medeiros Lima Amanda , Passos Apoliano Gomes Marília , Silva Moreira Tabita Aija
Published: January 2023

Os temas gênero e raça/etnia são de suma importância para a efetivação de uma coletividade justa na contemporaneidade. A partir de demandas em uma instituição de ensino federal do Sertão, desenvolvemos um projeto de extensão com Rodas de Conversa interdisciplinares que abordavam as matrizes opressoras, racista e sexista da sociedade brasileira. Os debates passavam pelas desigualdades interseccionais, raça e racismo no Brasil, empoderamento, corpo e gênero e representatividade. Orientadas pela Pedagogia Dialógica freireana e pela interculturalidade defendida pela Pedagogia Decolonial, objetivamos difundir obras dos feminismos afrodiaspóricos visando a problematização da realidade escolar e do sertão, para contribuir com a construção de uma cultura antirracista e anticisheteropatriarcal.
Recent Advances in Matrix Metalloproteinase Inhibitors Research
Authors: Michaelides Michael R. , Curtin Michael L.
Published: January 2023

Excess MMP proteolytic activity has been associated with a wide variety of pathological conditions such as arthritis, cancer and heart failure. The potential utility of MMP inhibitors as therapeutic interventions in these diverse and important disease states has led to an intense effort toward the development of such inhibitors.
The first generation of compounds were peptide-like broad spectrum inhibitors, active
against a broad range of MMPs. However, the induction of musculoskeletal side effects seen in clinical trials with these agents has emphasized the need for a better understanding of the role that each of the MMPs plays in normal tissue turnover and disease progression. Advances in our ability to engineer and synthesize selective inhibitors as well as the discovery of small molecule, non-peptidic inhibitors has spurred an intense effort to identify potent and bioavailable second generation compounds. There are now several such compounds targeted against various subsets of the MMPs in clinical development. This review will focus on the design and structure activity relationships of these second generation compounds.
β-Lactamases of Increasing Clinical Importance
Authors: Bush Karen
Published: January 2023

Resistance to β-lactam-containing antimicrobial agents continues to increase, frequently due to the presence of β-lactamases in Gram-negative bacteria. Over the past twenty-five years broad-spectrum enzymes such as TEM- and SHV­ variants and the metallo- β-lactamases have become more prolific. As a result of the ability of plasmids to continue to acquire additional resistance determinants, many of the -lactamase-producing Gram-negative pathogens have become multi-drug resistant. In combination with decreased permeability, the organisms can become virtually untreatable with current therapies.

The major groups of β-lactamases that pose the most serious therapeutic problems include the extended­ spectrum β-lactamases, the plasmid-mediated cephalosporinases, the inhibitor-resistant TEM- or SHV­ derived β-lactamases and the carbapenem-hydrolyzing β-lactamases. Those enzymes that can be transferred on mobile elements are the most serious of the newer β-lactamases, and include enzymes in each of the four groups outlined above.
The Reactivity of β-Lactams, the Mechanism of Catalysis and the Inhibition of β-Lactamases
Authors: Page Michael I
Published: January 2023

Four membered -lactam rings do not show unusual reactivity compared with their acyclic amide analogues and there is no evidence of concerted mechanisms for nucleophilic substitution reactions at the carbonyl centre. The identity of the general base/acid catalyst in the serine β-lactamases, which catalyse the hydrolysis of
β-lactams, is unknown. There are no ideal transition state analogue inhibitors for these enzymes which involve several intermediates and transition states. The class C
serine β-lactamase enhances the rate of phosphonylation of its active site serine residue by a similar magnitude to the enzyme rate enhancement factor for the hydrolysis of β-lactams. Comparisons are made between the stereochemical consequences of tetrahedral and trigonal bipyramidal intermediates for hydrolysis and phosphonylation respectively. Class B zinc β-lactamases are inhibited by thiol dipeptides with a D configuration at the cysteine centre analogous to the L configuration at C6 in penicillins. The mechanism of hydrolysis catalysed by the metallo β-lactamases probably involves a di-anionic tetrahedral intermediate stabilised by zinc(II).
Relationship between Jordanian Undergraduate Nursing Students' Perception of Empowerment and the Academic Satisfaction: Descriptive Study
Authors: Al-niarat Tahany , Abomoghli Fathieh
Published: January 2023

Background

Nursing students' perception of empowerment has an important impact on their learning process and learning outcomes.

Aim

This study aimed to assess the relationship between undergraduate nursing students' perception of empowerment and their academic satisfaction in Jordan.

Methodology

A descriptive, correlation design was used in this study, 164 fourth-year nursing students were selected to participate by convenience sampling method. The universities with the largest number of students were selected according to region (north, middle, south), and sectors (3private and 2public). The data collection methods included are: an Arabic version of self-reported questionnaires, the Learner Empowerment Scale (LES) to assess nursing students' perception of empowerment, and The Undergraduate Nursing Students Academic Satisfaction Scale (UNSASS) to assess nursing student’s agreement with academic satisfaction.

Results

Data were analyzed using descriptive and inferential statistics, 164 out of 184 students completed and returned the questionnaires with a response rate of 90%. Participants showed moderate perception of empowerment with a mean score is 79 out of (0-140) (SD=17.35). Pearson analysis showed a strong correlation between students' perception of empowerment and their academic satisfaction at all subscales: In-class teaching, clinical teaching, program design and delivery, and support and resources respectively as following: r (162) = +.37. P<0.01, r (162) = +.27, p<0.01, r (162) = .26, p<0.01, and r (162) = .30, p<0.01.

Conclusion and Implications

This is the first study conducted in Jordan that contributed to the body of literature on undergraduate nursing students' perception of empowerment and the relation of their satisfaction with learning environment. The results highlighted the essence of teaching-learning context and methods to empower the students. Thus, more efforts should focus on clinical training, clinical placement, and diversity of teaching strategies to match the educational requirement to reduce the theory-practice gap.
Decoding Vehicle Motion Data on the Internal Network
Authors: Ghadi Maen Qaseem
Published: January 2023

Background

Encrypting functions of vehicle internal networks make the lives of third parties more difficult since, in most cases, the meaning of messages carried by the CAN bus is not disclosed

Objectives

This paper proposes a reverse engineering method to discover, to a large extent, the semantics of CAN messages in a vehicle internal network.

Methods

A filtering mechanism has been applied that includes several statistical processes to interpret the codes of CAN messages. The speed change function of a vehicle has been chosen as an example to be followed in the development steps of this approach to predict the motion mechanism of the vehicle. The selected codes were verified by developing a multilevel model that relates the hierarchical relationship between the bytes and IDs and their impact on the speed factor.

Results

The most influential IDs and bytes on vehicle speed function were: ID 512, ID 520, ID 664, and B2, B4, B6, respectively.

Conclusion

The selected codes used to model the observed speed do not mean they all share the speed function, but there is a good possibility that at least some fulfill this function. However, the same methodology can be applied, with some optimization, to detect other semantic messages in the CAN network based on the expected type of data.
Nanostructured Etodolac Carriers in Transdermal Gel: Optimization and
Characterization
Authors: Patil Poonam , Shirkhedkar Atul
Published: January 2023

Aims:

To optimize, formulate, and evaluate a Nanostructured Lipid Carrier (NLC)
based transdermal gel of Etodolac (ETD).

Objective:

To avoid issues of conventional route ETD administration like first pass metabolism,
gastric ulceration, hemorrhage, and being a class-II drug with less solubility. A transdermal gel of
nanostructured lipid carrier for ETD has been developed. Formulation will execute faster onset of
action, increased penetration, permeation with extended release of the drug for a longer duration.

Methods:

A central composite 32 factorial design is used to plan experiments. NLCs are prepared
by the method of melt emulsification and ultrasonication. Compritol 888ATO and Miglyol are
used as solid and liquid lipid phases. Surfactant Pluronic F68 showed a significant effect on particle
size, entrapment efficiency, and drug release. Particle size characterized using photon correlation
spectroscopy and scanning electron microscopy. Cumulative drug release studied using an
artificial diffusion cell and a dialysis membrane. A skin permeation study was performed using
goat skin at 32°C ± 0.5°C. The efficacy of the NLC gel was verified using a pharmacodynamic
study followed by stability study for 3 and 6 months.

Results:

The optimized batch of ETD NLC found spherical with a 241.3 nm particle size with
0.392 PDI,-29 mV zeta potential. Entrapment efficiency and cumulative drug release were found
to be 64.21 ± 1.23% and 70.12 ± 2.10% (after 12 hours), respectively. All batches followed zeroorder
drug release kinetics and non-Fickian (Super Case II transport) with 0.1619 mg/cm2/hr
transdermal flux. The NLC gel of ETD showed a quick onset and lengthened therapeutic activity
until 24 hours compared to the micellar ETD gel.

Conclusion:

Etodolac NLC batch successfully optimized using central composite design. The
relationships between the components of the NLC-total lipid:drug and surfactant-and the outcomes-
particle size,%entrapment and% drug release-were better understood by examining several
contour plots. The results of the experimental and predicted formulations were found to be in good
agreement with slight bias, demonstrating the reliability of the optimization process.
NMR-based Phytochemical Profiling of Palmyra Palm Syrup Infused with
Dry Ginger, Black Pepper, and Long Pepper
Authors: Reshma Mullan Velandy , Lankalapalli Ravi Shankar , Athira Ambili Sasikumar , Kiruthika Ramkumar , Ingaladal Nagaraja , Krishnakumar Karunakaran Anitha , Raveena Natakkakath Kaliyathan , Gopika Biju
Published: January 2023

Background:

Trikatu, a vital ingredient in many Indian Ayurvedic drugs, is a consortium of
three spices, viz. dry ginger, black pepper, and long pepper, known for its peculiar pungency. To convert
Trikatu into a widely acceptable palatable form, we blended these three spices in a decoction form
and added them to syrup prepared from palmyra palm neera, which resulted in ‘Trikatu Syrup’ (TS).
Recently, we reported in vivo immunomodulatory properties of TS.

Introduction:

The immunomodulatory effects of spices are attributed largely to the presence of certain
phytochemicals. The importance of phytochemicals in spices as immunomodulatory agents necessitate
a thorough investigation of these bioactives in formulations comprising spices. In the present study, we
have focused on understanding the retention of spice and syrup-based phytochemicals in the formulated
product that assists in product standardization of TS.

Methods:

NMR serves as a highly reliable tool for explicit structural confirmation of phytochemicals
when compared to HPLC or mass spectrometry tools. NMR spectra of a phytochemical, whether in
pure form or when the phytochemical is a part of the mixture, enable qualitative and quantitative studies
with a mixture of phytochemicals in organic extracts of food matrices. Hence, the NMR spectral
comparison of compounds isolated from the organic extracts of TS is described here.

Results:

Fractionation of TS using Diaion® HP-20 resulted in the partitioning of compounds based on
their polarity. Purification of the acetone fraction by column chromatography aided in the efficient
isolation of compound 1 (pellitorine), compound 2 (piperine), compounds 3-5 (trienamides), and compound
6 (pipataline). Acetonitrile fraction yielded compound 7 (uridine) and compound 8 (3-O-methylmyo-
inositol), which were neither reported in the three spices nor palmyra palm. A qualitative display of
the acetone fraction of TS with its phytochemicals 1-6 served as a fingerprint of TS.

Conclusion:

In summary, TS, a palatable spice-based nutraceutical in palmyra palm syrup with immunomodulatory
potential, was thoroughly investigated for the phytochemical composition of its organic
fractions. The process of fractionating TS using Diaion® HP-20, subsequent flash purification,
and column chromatography facilitated the isolation of prominent phytochemicals. We report the utility
of NMR as a reliable and efficient tool for fingerprinting phytochemicals in formulations, nutraceuticals,
etc., which assists in ascertaining their authenticity.
Vertebrobasilar Dolichoectasia, An Unusual Cause of Trigeminal Neuralgia: A Case Report
Authors: Pradana Wisniardhy Suarnata , Yueniwati Yuyun
Published: January 2023

Background: Trigeminal neuralgia is a facial pain syndrome that generally occur unilateral following the sensory distribution of the trigeminal nerve. It is classified into trigeminal neuralgia with no apparent cause, classic trigeminal neuralgia, which is caused by vascular compression of the trigeminal nerve root, and secondary trigeminal neuralgia caused by major neurological diseases such as cerebellopontine angle tumour or multiple sclerosis.Case: A 60 years old male, complained of pain in the right face since >4 years ago, intermittent, radiating from around the upper right molars to the right face, like an electric shock, and appeared mainly when chewing. MRI and MRA examination of the patient revealed vertebrobasilar dolichoectasia causing displacement of the pons and right trigeminal nerve.Discussion: Vascular compression of the trigeminal nerve root is the most common cause of trigeminal neuralgia, which is commonly caused by small arteries such as the superior cerebellar artery. Vascular compression due to large arteries such as the basilar and vertebral arteries may occur in a minority of cases. MRI is an examination that plays an important role in cases of trigeminal neuralgia, because it can assess the pathology of cerebellopontine angle area, as well as assess the presence of neurovascular compression and morphological changes of the trigeminal nerve roots.
Evaluation of the implementation of the Teaching Campus program in elementary school: A phenomenological approach
Authors: Indriani Fitri Indriani , Holisah Holisah
Published: January 2023

This study aims to evaluate the implementation of the teaching campus program using an evaluation model from Stufflebeam consisting of Context, Input, Process, and Product (CIPP). The research used a qualitative method with a phenomenological approach. Data were collected by interview, observation, and documentation techniques. The data validity was done by triangulation of styles and sources. Miles and Huberman's techniques were used in data analysis: data collection, data reduction, data presentation, and conclusion. The informants include principals, teachers, students, and students as implementers of the Teaching Campus program. The results show that the implementation of the teaching campus program in elementary schools has been carried out properly in the aspects of CIPP and has a positive impact on the quality of education, especially on the program targets, namely numeracy, literacy, technology, and administration. The program's success is inseparable from various supports such as competent human resources (students and supervisors), the openness of the head of the local education office, and the cooperative school. The inhibiting factors include a lack of socialization about the program in the school, so there is a misunderstanding in giving assignments to students. On the other hand, the Teaching Campus program often accounts for errors, so the reporting of activities is not smooth, and students are often late filling out the log book because they are busy with lectures. The organizers can consider the results of this study to improve the quality of the implementation of the teaching campus program to run optimally.
An evaluation of the effectiveness of the English Upgrading program for TOEFL in an Indonesian university using the CIPP model
Authors: Labibatussolihah Labibatussolihah , Adriani Nour Muhammad
Published: January 2023

Human resources capacity building is a vital part of institutional development, especially in the educational field, such as the university. As an academic language, English skills are highly needed among lecturers to improve the quality of institutions in general. What is the effectiveness of an English preparation course for lecturers in an Indonesian university during the pandemic time? Using Stufflebeam’s CIPP model, this study aims to measure the quality and make recommendations on what should be improved or changed from such activity. There were 25 participants, two tutors, and one program coordinator involved as an informant. An online questionnaire was administered, as well as an in-depth interview with the tutors, coordinator, and selected participants. The results show that (1) the context is suitable to the condition, resources, and needs of the institution as well as participants. (2) In the Input section, the curriculum and variations in learning methods need to be further developed. (3) In the process section, the obstacles faced were the lecturer’s workload, which should be adjusted during the course to make them focus on the program. (4) In the product section, a high level of satisfaction was found among the participants, with an overall positive review of its merit. There is still room for improvement. One of them is to follow up on participants’ progress after the program is ended. An evaluation sheet or survey should be administered after the program is finished to assess the quality of the tutors and participants’ satisfaction with the training.
Rasch model for the need assessment instrument of academic guidance and counseling program in junior high school
Authors: Farozin Muh , Astuti Budi , Sanyata Sigit , Titi Dwitias , Nurmalasari Ela , Sutanti Natri
Published: January 2023

Developing an instrument for the need for academic guidance and counseling topics is a strategic step to support the needs assessment carried out by guidance and counseling teachers and counselors in schools. The development of this instrument had been carried out by Arfalah using exploratory factor analysis. This study aims to analyze the instrument using the Rasch model. The research procedure began with collecting data from two integrated online needs assessments of academic guidance and counseling instruments. The content validity test involved six experts, and the field test involved 111 students from three junior high schools in Yogyakarta. Data were analyzed using Winsteps version 3.73 according to Fisher’s five criteria for a good instrument. The content validity test showed Aiken’s coefficient of 0.71, considered in the high category. Meanwhile, the results of the Rasch test showed the item response model. The analysis also indicated high reliability on both instruments above 0.90 and Cronbach’s alpha value of 0.98. Five items were decided to be maintained based on the misfit test explored. The accuracy and focus of the instruments in revealing the need for academic guidance and counseling topics for high school students indicated a number above 40% and a fairly good level of instrument contamination, which was below 10%.
Does the policy regarding the role of the national examination in determining graduation affect student achievement?
Authors: Rasmuin Rasmuin
Published: January 2023

From 2004 to 2018, the national examination (NE) has undergone three policy changes regarding its role in determining graduation. The NE score was decided to be the sole determining factor for student graduation in the period 2004 to 2010, with the school examination score being the determinant of student graduation from 2011 to 2015 and no longer a determinant of student graduation from 2016 to 2018 period. This study aimed to analyze the pattern of influence of the NE policy as a determinant of graduation on student achievement at junior, senior, and vocational high schools. This study used data on student achievement for 15 years in the subjects tested on the NE obtained from the Research and Development Center of the Indonesian Ministry of National Education. Data analysis was done descriptively by estimating students' mean achievement on the NE and then analyzing the mean trend. By analyzing the trend of student scores' mean on the subjects tested on the NE at the junior high school, senior high school, and vocational high school levels, the mean tends to increase in the period 2004 to 2010, tends to be less stable and decrease in the period 2011 to 2015, and tends to decline again when the NE score is no longer used as a determinant of graduation in the period 2016 to 2018. These results indicate that the policy on using NE scores in determining graduation influences student achievement in junior high school, senior high school, and vocational high school levels.
Andrij Potebnia – a forgotten hero of Polish-Ukrainian relations
Authors: Kamionka Mateusz
Published: January 2023

Poland and Ukraine have a lot of problems in establishing bilateral remembrance policy, first of all because of the history after World War I, and as well in topic connected to – mostly in frame of stereotypes – the history during The Polish-Lithuanian Commonwealth. Deep russification and anti-Polish state policy, which lasted from XVIII to XXI century, implemented by Russians in Ukraine should be underlined as well. Not only “Ukrainian” meant second category, but also world “Polski Pan” (Polish Lord) had a definite pejorative tone then – it was used even in propaganda during Soviet Invasion in 1920 and 1939. In article will ipso facto be presented one of the forgotten heroes (definitely in Ukraine) which can be a symbol of bilateral international relations. Andrij Potebnia should be one of main actors of building Polish-Ukrainian memory cooperation. The text not only reveals how memory of this officer is presented in Polish Internet today, but also how this forgotten hero of two nations is remembered by local communities in Poland.
Traditionalist aspect of sociocultural practices: historical memory in the conditions of information war
Authors: Kovalskyi Hryhorii
Published: January 2023

The article aims to study the role of philosophical traditionalist concepts in socio-cultural practices and the development of historical memory. Historical memory is proven to be a tool for transferring social experience, as well as scientific and non-scientific knowledge about the shared past and an entire system of self-identification of society. At the same time, historical memory is a dimension of the individual and collective memory of the historical past, representing it from a symbolic perspective. As a sociocultural phenomenon, historical memory accumulates a set of images and collective perceptions, reproducing the community's cultural and historical experience. The nature of society implies that previous socio-historical stages are causally related to the present. The current historical period forms the basis of the future. The connection of the present with the past is the basis of tradition. Cognition of traditional symbols is performed with the help of a particular "symbolic method" of analogies. The superhuman in tradition is revealed in the direct experience of the sacred, after which the transcendental realm begins. Attributing to tradition a metaphysical, not just socio-cultural status, traditionalists are guided by the existential integrity of human existence in the system of the tradition, the interconnection of all its manifestations, and the connection between the revealed and unrevealed levels of reality.
Social transformations and distribution of pirated media content on the example of video games
Authors: Maliuk Yevhen
Published: January 2023

The article examines the history of the distribution of pirated content and methods of combating it using the example of video games. The ambivalent impact of the phenomenon of piracy on sociocultural processes in societies, especially those that radically changed their social structure at the end of the 20th – beginning of the 21st century, is demonstrated. The author proceeds from the fact that piracy arose on the basis of the absence of the so-called “copyright culture” transformed societies, allowed individual economic actors to get rich illegally and quickly, but at the same time acted as a massive display of technical intelligence, a creative impulse to create one’s own video content in these societies and the formation of relevant regional markets, and also contributed to the development of many technical talents currently working on digitalization of socio-economic processes around the world.
According to the examples of piracy described in the article, four main motives for its spread are highlighted, namely: economic, activist, archival and creative motives. As demonstrated in the study, these motives shape relevant social patterns and change over time, as can be seen in the example of creative piracy, which was widespread in the pre-Internet era and has almost disappeared in the modern one. Although in most cases of piracy the main motive is economic, which leads to great losses for copyright holders and authors, not all methods are unequivocally harmful. For example, activist piracy is a form of social protest and allows to demonstrate one’s dissatisfaction with the policy of rights holders through the practice of “wrong” consumption; the archival motive often works in the “gray zone” of copyright and allows preservation of those products, the rights to which were handed over to the rights holders that actually no longer exist.
Kajian Pertumbuhan dan Hasil Lima Aksesi Kacang Hijau (Vigna radiata L.)
Authors: Anhar Tahtihal , Respatie Dyah Weny , Purwantoro Aziz
Published: January 2023

Produksi kacang hijau di Indonesia pada tahun 2008-2018 cenderung mengalami penurunan. Pada tahun 2018 produksi kacang hijau di Indonesia mencapai 241.334 ton, dan pada tahun 2018 produksi kacang hijau di Indonesia mengalami penurunan menjadi 234.718 ton. Salah satu faktor penting yang mempengaruhi produktivitas kacang hijau yaitu keterbatasan varietas unggul baru, sehingga perlu dilakukan kajian mengenai galur-galur kacang hijau baru sebagai calon varietas unggul baru. Tujuan penelitian yang dilakukan yaitu untuk mengetahui pertumbuhan dan hasil lima aksesi kacang hijau dibandingkan dengan varietas pembanding. Penelitian ini dilaksanakan pada bulan September 2020 – Desember 2020 di Kebun Percobaan Tri Dharma Fakultas Pertanian UGM, Banguntapan, Bantul, Daerah Istimewa Yogyakarta. Penelitian ini menggunakan Rancangan Acak Kelompok Lengkap (RAKL) dengan tiga blok sebagai ulangan. Penelitian ini terdiri dari satu faktor perlakuan yaitu aksesi. Aksesi yang digunakan sebanyak lima (F2, F3.1, F3.2, F3.3, dan F3.4) dan (PK-H, VM-4, dan KTG) sebagai kontrol. Hasil penelitian menunjukkan bahwa pada pertumbuhan vegetatif antara aksesi F2 hingga F3.4 tidak berbeda nyata dengan varietas pembanding yaitu PK-H, VM-4, dan KTG. Pada parameter produktivitas dan indeks panen seluruh aksesi dengan varietas pembanding memiliki nilai yang sama yang menandakan bahwa aksesi F2 hingga F3.4 sudah sama dengan varietas yang sudah banyak dipasarkan dan perlu dikembangkan lebih lanjut.
Pemberian Berbagai Level Air dan Pengaruhnya Pada Pertumbuhan dan Hasil Tanaman Kedelai (Glycine max (L) Merr) Varietas Grobogan
Authors: Mahardika Yusthian Hendra , Simanjuntak Bistok Hasiholan
Published: January 2023

Faktor ketersediaan air tanah menjadi faktor pembatas pertumbuhan dan hasil kedelai. Oleh karena itu tujuan penelitian adalah mengetahui pengaruh pemberian berbagai level kadar air tanah terhadap pertumbuhan dan hasil tanaman kedelai varietas Grobogan. Tata letak penelitian dengan Rancangan Acak Kelompok (RAK), terdiri atas 4 perlakuan pemberian air sebanyak kadar air tanah 25% kapasitas lapang (P1), kadar air tanah 50% kapasitas lapang (P2), kadar air tanah 75% kapasitas lapang (P3), kadar air tanah 100% kapasitas lapang (P4). Masing-masing perlakuan diulang 6 kali. Data penelitian terdiri atas prolin daun, stress index (SI), tinggi tanaman, berat kering tanaman, jumlah polong per tanaman dan berat biji per hektar. Data dianalisis dengan Analisis Sidik Ragam dan dilanjutkan dengan Uji Beda Nyata (BNJ) dengan taraf kepercayaan 95%. Pemberian air mempengaruhi produksi prolin, pertumbuhan dan hasil tanaman kedelai varietas Grobogan. Akumulasi prolin dalam tanaman semakin meningkat ketika tingkat cekaman kekurangan air semakin tinggi.  Pemberian air 75% kapasitas lapang mengakibatkan cekaman kekeringan tanaman kelas rendah, sedangkan tinggi tanaman kedelai, bahan kering tanaman, jumlah polong, dan berat gabah tidak berbeda nyata dengan pemberian air 100% kapasitas lapang. Pemberian air 50% kapasitas lapang mengakibatkan cekaman kekeringan tanaman kelas sedang dan secara nyata menurunkan tinggi tanaman. Pemberian air 25% kapasitas lapang mengakibatkan cekaman kekeringan tanaman kelas tinggi dan pada kondisi demikian terjadi penurunan secara nyata pada tinggi tanaman, berat kering tanaman,  jumlah polong dan berat biji per hektar serta terjadi penurunan hasil hingga 69% jika dibandingkan dengan pemberian air 100% kapasitas lapang.
Karakterisasi Beberapa Aksesi Serai Wangi (Cymbopogon nardus L.) Asal Cianjur
Authors: Susilowati Mariana , Syukur Cheppy
Published: January 2023

Serai wangi (Cymbopogon nardus L.) merupakan tanaman aromatik yang kaya akan kandungan senyawa kimia penting terutama sitronela. Minyak atsiri dari tanaman serai wangi sering digunakan sebagai bahan baku utama berbagai industri. Perakitan varietas-varietas unggul serai wangi masih sangat diperlukan dalam rangka upaya peningkatan produksi serai wangi nasional. Pemanfaatan aksesi-aksesi dari sentra produksi serai wangi seperti Cianjur diharapkan dapat mendukung program pemuliaan serai wangi secara efektif dan efisien. Informasi genetik dari aksesi-aksesi lokal dapat diketahui melalui kegiatan karakterisasi. Tujuan dari penelitian ini adalah untuk mengetahui karakter morfologi kualitatif dan kuantitatif beberapa aksesi serai wangi hasil eksplorasi dari daerah Cianjur, Jawa Barat. Materi genetik yang digunakan pada penelitian ini adalah 10 aksesi Cianjur (SC1, SC2, SC3, SC4, SC5, SC6, SC7, SC8, SC9, dan SC10). Karakter yang diamati berupa karakter kuantitatif dan kualitatif. Dari hasil analisis menunjukkan bahwa aksesi SC1 merupakan aksesi terbaik dari Cianjur yang memiliki keunggulan pada semua karakter kuantitatif yang diamati terutama karakter panjang daun, tinggi batang, diameter batang, dan aroma daun yang tajam. Sekitar 75% karakter kuantitatif serai wangi Cianjur menunjukkan hasil korelasi antar karakter yang positif. Aksesi-aksesi dari Cianjur memiliki ciri-ciri yang sama yaitu batang berwarna VG 84B, pangkal daun berbentuk cekung, dan permukaan daun berwarna GGN 138C. Aksesi SC1 dan SC5 memiliki hubungan kekerabatan yang jauh dan berpotensi dikembangkan sebagai tetua persilangan.
Impact of Lockdown on Air Pollution: Evidence from the “2+26” Cities in the Beijing-Tianjin-Hebei Region
Authors: Wei Jialu , Chen Fuxing , LU Min
Published: January 2023

To prevent the spread of COVID-19 in China, many cities were locked down after January 23, 2020. Based on the panel data of the “2+26” cities from 10 January to 15 March 2020, this paper took the lockdown as a quasi-natural experiment and established a multi-phase DID model to investigate whether the lockdown measures significantly reduced air pollution in locked-down cities in the Beijing-Tianjin-Hebei (BTH) region. The core innovation of this paper is that we considered the urban immigration scale index as a mediating variable , which is rarely adopted in the existing literature, and we identified the relationships between the lockdown, the intracity migration index, the urban immigration scale index and air pollution. The results showed that compared with the non-locked-down cities, the lockdown significantly reduced air pollution. Furthermore, it was found that the lockdown reduced air pollution by reducing intracity migration and the urban scale of immigration. Moreover, compared with the corresponding period in 2019, air pollution was significantly reduced in the locked-down cities of the “2+26” cities. Air pollution is closely related to human activity, and green production and technological innovations are critical for reducing air pollution in the BTH region.
Medicinal use of the main Boldo Species in Brazil and in Lusophone Africa Countries
Authors: Amaral Jeferson Falcão do , Pafo Fáusia da Verónica Eduardo , Silva Amarildo Pereira da , Silva Fábio Morais da , Bandeira Nayara Cristina Rabelo , Oliveira Lucineide de Abreu , Oliveira Erasto Gonçalves de , Neto Luís Carlos Cavalcante , Silva Francisco Danilo Ferreira Costa da
Published: January 2023

The use of medicinal plants as an alternative source of treatment, prevention and cure of various diseases is a practice that comes with ancestry. Currently, the search for well-being and new forms of natural treatment without many chemicals, makes the demand for herbal medicines increase every day. Among these, we have the boldo, which has contributed to cure and alleviate some evil diseases such as: liver, poor digestion, stomach, and hemorrhoids. However, in Brazil, as well as in Portuguese-speaking African Countries - (PALOP) there is still a deficit or shortage in research involving this species. The objective of this work is to present a profile of the main boldo species and different forms of use in Brazil and in the PALOP countries (Angola, Cape Verde, Guinea Bissau, Mozambique and São Tomé and Príncipe) from the perspective of health and sustainability. To carry out the work, a narrative review of the literature was carried out with a descriptive character, through the selection, reading, analysis and interpretation of articles published in full in scientific journals, in Portuguese and in English, available on the internet. In the search for articles, the Boolean AND operator was used. To better obtain the results, it was necessary to use the following keywords: medicinal use, boldo, Brazil, sustainability and medicinal use, Lusophone African countries, PALOP and sustainability. The chosen platforms were SciELO, LILACS and Google and Academic. The use of the highest incidence of 01 species of boldo in Portuguese-speaking African countries, known as Boldo-Africano (Plectranthus barbatus), was identified. In Brazil, 08 species are cultivated, being used commercially the species Vernonia amygdalina, (Gymnanthemum amygdalinum), African Bilberry/Garden Bilberry (Plectranthus barbatus), Boldo possum (Plectranthus backpacks) and Chilean Boldo (Peumus boldus, Monimiaceae), the latter being imported. In Brazil, the health strategies of the Family Health Program - PSF contemplate another look at the needs of the communities assisted by the program, while in Lusophone Africa, the health systems have a small and poorly distributed chain of medicines that, for the most part, do not even arrive for a third of the population. The study points to the need to carry out more research on the subject, as the results of these research can be extremely important in the dissemination of the correct way of use and indication, which can contribute to the preservation of species and maintenance of the cultural legacy of biodiversity, knowledge base on the use of medicinal plants and herbal medicines, such as boldo.
Targeting Factors of Ecotax Based on Life Cycle Assessment for Select Criteria Mechanism using waste to Energy Technology of Environmental Law and its Enforcing Regulations
Authors: M. Llarena Zharama
Published: January 2023

Every drug product, with its apparent patent and trademark from European Patent Commission (EPC), must exhibit its safety utilization starting from its ecological cultivation up to its warranty disposal back to the environment termed as Life Cycle Assessment of drugs. Climate change may be influenced and worsened by several determinants in which pharmaceutical sector may play a big role to environmental pollution and may eventually lead to risks of developing health problems due to environmental toxicities. Therefore, there is a crucial need for remediating drug wastes into renewable energies as corporate responsibility of environmental taxation for the advocacy of Sustainable Development as promoted and regulated by Kyoto Protocol of United Nations Millennium Development Goals of economic prosperity and safety of the public. This paper aims to delineate the waste to energy technology functions for addressing its problems and concerns in carbon tax such as the quantity of renewable power percentage, the amount of greenhouse gases of climate change and its environmental pollutants from waste disposal of expired and used drugs, the prevalence of morbidity and mortality rates in relation to environmental exposure to hazardous substances, and its relative monetary progress and success. Kinetic modelling of equations and its MATLAB simulation code is important for application of waste to energy technology for Sustainable Development. Therefore, delineation of carbon tax in kinetic modelling is quite necessary in resolving issues in economy, society, and environment as exhibited in SELECT criteria mechanism of decision making.
¿El arte promueve la obesidad? La obra de Fernando Botero
Authors: Armendáriz Beltrán Catalina
Published: January 2023

La representación de la figura humana ha sido protagonista del arte desde la prehistoria; sin embargo, la estética del cuerpo humano y la manera de representarla ha cambiado con el paso de los siglos. En este sentido, las carac­terísticas del cuerpo humano, que se presentan en las obras artísticas de pinturas y la escultu­ras corresponden a lo socialmente aceptado en la época en cuanto a la belleza, aunque en al­gunos casos pueden ser expresiones de crítica, rechazo o sátira.
Atención odontopediátrica en niños con síndrome de Heterotaxia Visceral Asplénica (HVA). Una revisión narrativa
Authors: Lara-Pérez Alba Jhovana , Ávalos-Arenas Verónica
Published: January 2023

Introducción. La Heterotaxia Visceral Asplénica (HVA), es un síndrome caracterizado por anormalidades relacionadas con la disposición interna de los órganos del cuerpo. Este tipo de pacientes requiere un monitoreo y atención odontológi­ca más frecuente y supervisada, considerando el riesgo de infecciones sistémicas vinculadas con la caries y gingivitis. Objetivo. Presentar el estado del arte del conocimiento so­bre el síndrome HVA y la atención odontopediátrica requerida. Desarrollo. La HVA está comúnmente asociada a una enfer­medad cardiaca congénita cianótica, disposición anormal de las vísceras abdominales y agenesia del bazo. Dentro de sus factores predisponentes, contribuyen factores ambientales y genéticos que, de manera independiente o conjunta, actúan justo cuando se establecen los ejes cordales izquierdo-dere­cho durante la tercera semana de gestación. Los pacientes sin bazo o con cardiopatías congénitas graves tienen un riesgo elevado de desarrollar infecciones potencialmente mortales (OPSI), presentándose en un 50 a 80% de los casos. En pa­cientes con HVA, la susceptibilidad a infecciones graves es mayor debido a que la función de defensa del bazo está afec­tada, lo que provoca mayor susceptibilidad de bacteremia, por lo cual, se debe tener en cuenta este tipo de pacientes en el tratamiento odontológico. Conclusión. Es necesario imple­mentar un programa estomatológico preventivo y restaurativo (no invasivo) en estos pacientes lo antes posible. Hacer énfa­sis en los controles personales de biopelícula, higiene bucal exhaustiva, aplicaciones de barniz de flúor, asesoramiento dietético, selladores de fosetas y fisuras, mantenimiento de una buena salud gingival y periodontal, la erradicación de ca­ries, lesiones y procesos de infección local.
Envejecimiento, cultura y pandemia de Covid-19 en Chile: reflexiones desde la gerontología rupturista
Authors: Piña-Morán Marcelo , Olivo-Viana María Gladys , Martínez-Matamala Carlos
Published: January 2023

La gerontología analiza el proceso de envejecimiento y vejez con un enfoque interdisciplinario, considerando, al menos, los componentes biológico, psicológico, social, político, histórico, educativo, cultural y económico. Cuando el énfasis se sitúa en la visión socioantropológica, la perspectiva sociocultural es un eje relevante de considerar para analizar prácticas significantes de las personas mayores.1 En este sentido, uno de los desafíos emergentes es el envejecimiento poblacional, esencialmente desde lo cultural y la forma en la que impacta en la calidad de vida de las personas mayores.
Envejecimiento en México (ENASEM). Una herramienta para el estudio del envejecimiento saludable.
Authors: Sánchez-Rodríguez Martha A.
Published: January 2023

El envejecimiento de la población es un fenómeno mundial que ha ido en aumento en las últimas tres décadas en la mayoría de los países en el mundo, aunque en algunos como los europeos comenzó hace más tiempo; nuestro país no es la excepción. Esto obedece a la disminución de la tasa de fecundidad y el aumento de la esperanza de vida por el incremento en el cuidado y la mejora de los sistemas de salud, favoreciendo el aumento en la población de 60 años y más
A NEW EVALUATION METHODOLOGY APPLICATION OF DRY SEVERITY FOR THE CITY OF CAMPINA GRANDE-PB
Authors: Nascimento Maxsuel Bezerra do , Silva Tássio Jordan Rodrigues Dantas da , Medeiros José Ludemario da Silva , Cezário Janaina Aparecida , Paiva William de , Santos Laércio Leal dos
Published: January 2023

Droughts come from natural factors, and when they occur, cause changes in the climate, whether on a punctual or diffuse scale, and this cycle is constantly repeated, but in recent decades these impacts have increased with human actions from deforestation and burning of fossil fuels. Thus, the objective of this work is to employ a new application of the Drought Index methods (IAC, IPN and MD) to the data from the historical rainfall series of the municipality of Campina Grande - PB in the state of Paraíba, in order to classify the data on a monthly and annual scale, in order to identify the intensity over the years studied in this research. The pluviometric data used in the research correspond to the historical series from 1980 to 2019, which are divided into monthly precipitation data, provided by the Northeast Development Superintendence, National Institute of Meteorology and the Paraíba Water Management Executive Agency. The proposed methodology, in addition to the new standardization of the Drought Intensity Index (IIS), proposes a new characterization of the final rainfall condition or drought severity index. Finally, it allows environmental agencies and managers better conditions to adapt to problems related to drought and extreme rainfall, for greater management of water resources.
PÓS-TRATAMENTO DE EFLUENTES DA INDÚSTRIA DE PANIFICAÇÃO E CONFEITARIA POR WETLANDS CONSTRUÍDAS CONSIDERANDO DIFERENTES TEMPOS DE DETENÇÃO HIDRÁULICA
Authors: Kurpel Kennithy , Souza Kely Viviane de , Bonete Izabel Passos
Published: January 2023

A fitorremediação com macrófitas é uma alternativa para recuperação de ambientes contaminados com efluentes. Desta forma, foram desenvolvidos os Sistemas Wetlands Construídas (SAC’s), que são projetados para reproduzir sistemas wetlands naturais. O objetivo do trabalho foi avaliar o desempenho das Wetlands construídas em escala piloto, como pós-tratamento de efluentes da Indústria de Panificação e Confeitaria, operados em diferentes tempos de detenção hidráulica, coletando efluentes após os tratamentos em reatores anaeróbios seguidos de lagoa de aeração. As atividades foram separadas em duas fases: (1) Caracterização do efluente bruto, construção das unidades piloto dos SAC’s, período para estabilização do leito e aplicação de mudas de macrófitas aquáticas (Juncus effusus e Syngonium podophyllum). 2. Aplicação dos efluentes líquidos nos leitos piloto, coleta do efluente final para avaliação da eficiência de remoção de parâmetros específicos conforme os períodos de detenção hidráulica pré-estipulados de 5, 10, 15, 20, 25, 40 e 45 horas. Para avaliação da eficiência de remoção considerou os parâmetros: demanda química de oxigênio (DQO) e nitrogênio amoniacal (NH4+). Os resultados mostraram que o maior tempo de detenção hidráulica (> 40 h) foram melhores e influenciaram positivamente na redução de valores de DQO. Dentre as espécies de macrófitas testadas, observou-se significância e melhor eficiência de J. effusus na redução de valores de nitrogênio amoniacal, enquanto a espécie S. podophyllum obteve melhor resultado para a variável DQO. Portanto, é possível concluir que o sistema wetlands foi eficiente na redução de NH4+ dos efluentes da lagoa aerada e DQO dos efluentes oriundos do reator anaeróbico.
Thermal Stress Analysis and Optimization of FSW Process on UHMWPE by Using Hexagonal Tool Profile
Authors: S Mr. Rajkumar. , M Mr. Pradeep , M. P Mr. Mano Bharth
Published: January 2023

Abstract: The use of polymeric materials has grown widely in various sectors such as packaging, building, electronic, automotive, and aerospace industries. Particularly, Ultra-High Molecular Weight Polyethylene has wide engineering applications and is used in large quantities in automotive oil pans, gears, slides, cams, bearings, fluid reservoirs, and the sports industry. Friction Stir Welding (FSW) is a solid-state process in joining thermoplastic materials. In this investigation, FSW process must be applied to join a UHMWPE plate of 8 mm thickness with specially designed hexagonal tool pin profile. The aim of this study is to examine the effect of main friction stir welding (FSW) parameters on the quality of UHMWPE plate welds. FSW machine, using a tool with a stationary shoulder and no external heating system. The welding parameters studied were the tool rotational speed which varied between 1300 and 1500 (rpm); the traverse speed which varied between 15 and 25 (mm/min), and the axial force ranging from 8 to 10 (KN). Good quality welds are achieved without using external heating, when the tool rotational speed and axial force are above a certain threshold. For high rotational speed and axial force welds have poor material mixing at the retreating side and mild voids at the nugget, tensile strength also obtained very poor. The hardness angle distortion and bead geometry also evaluated. Taguchi design optimum parameters and ANNOVA were found.