bluuebunny/crossref_metadata_2025 huggingface dataset:
In Defense of Interiority: Melvin Edwards’ Early Work
Authors: Archias Elise
Published: December 2023

Melvin Edwards made his first abstract sculptures at the beginning of the contemporary period in the early 1960s, but the ways he held on formally to a modern notion of “interiority” in his Lynch Fragments series provide us with an underexamined aesthetic position in contemporary art. Edwards offered nuanced relationships between interior and exterior at a moment when concepts of “interiority” and “self” were under the most strain in contemporary art practice. If we consider this turn away from interiority—and toward surface, emptiness, system, and dematerialization—to be, in part, a symptom of the pressure exerted by the commodity form on art viewers’ sensibilities after 1955, then the stakes of Edwards’ choice not only to use found metal objects, but to compose them around an active rather than empty center, feel higher. By comparing the sculpture Mojo for 1404 (1964) with the Bichos (1960–1965) of Lygia Clark, the distinctiveness of Edwards’ project emerges even more strongly. Clark responded to the crisis of interiority with shiny metal sculptures whose interiors were constantly being flipped inside-out. By contrast, Edwards’ art was motivated by the struggle for racial justice, and it persistently spoke its desire for grounded, scarred personhood in an aesthetic language that required viewers to recall their own interiority.
Sesamin’s Therapeutic Actions on Cyclophosphamide-Induced Hepatotoxicity, Molecular Mechanisms, and Histopathological Characteristics
Authors: Jali Abdulmajeed M. , Alam Mohammad Firoz , Hanbashi Ali , Mawkili Wedad , Abdlasaed Basher M. , Alshahrani Saeed , Qahl Abdullah M. , Alrashah Ahmad S. S. , Shahi Hamad Al
Published: December 2023

Cyclophosphamide, an alkylating agent integral to specific cancer chemotherapy protocols, is often curtailed in application owing to its significant hepatotoxic side effects. Therefore, this study was conducted to assess the hepatoprotective potential of sesamin, a plant-originated antioxidant, using rat models. The rats were divided into five groups: a control group received only the vehicle for six days; a cyclophosphamide group received an intraperitoneal (i.p.) single injection of cyclophosphamide (150 mg/kg) on day four; a sesamin group received a daily high oral dose (20 mg/kg) of sesamin for six days; and two groups were pretreated with oral sesamin (10 and 20 mg/kg daily from day one to day six) followed by an i.p. injection of cyclophosphamide on day four. The final and last sesamin dose was administered 24 h before euthanasia. At the end of the experiment, blood and liver tissue were collected for biochemical and histopathological assessments. The results indicated significantly increased liver markers (AST, ALT, ALP, and BIL), cytokines (TNFα and IL-1β), caspase-3, and malondialdehyde (MDA) in the cyclophosphamide group as compared to the normal control. Additionally, there was a significant decline in antioxidants (GSH) and antioxidant enzymes (CAT and SOD), but the sesamin treatment reduced liver marker enzymes, cytokines, and caspase-3 and improved antioxidants and antioxidant enzymes. Thus, sesamin effectively countered these alterations and helped to normalize the histopathological alterations. In conclusion, sesamin demonstrated the potential for attenuating cyclophosphamide-induced hepatotoxicity by modulating cytokine networks, apoptotic pathways, and oxidative stress, suggesting its potential role as an adjunct in chemotherapy to reduce hepatotoxicity.
Claudin18.2 in Advanced Gastric Cancer
Authors: Inamoto Rin , Takahashi Naoki , Yamada Yasuhide
Published: December 2023

Globally, the fifth most common cancer and the fourth leading cause of cancer-related mortality is gastric cancer (GC). Recent clinical trials on solid tumors enrolled patients who possess druggable genetic alterations, protein expression, and immune characteristics. In gastric or gastroesophageal junction (GEJ) cancers, trastuzumab combined with first-line chemotherapy in human epidermal growth factor receptor 2 (HER2)-positive patients and ramucirumab combined with second-line paclitaxel remarkably prolonged overall survival (OS) compared with chemotherapy alone, according to phase 3 trial results. Recently, immune checkpoint inhibitor (ICI) monotherapy was approved as third- or later-line treatment. Chemotherapy plus ICIs as first-line treatment exhibited improved survival compared with chemotherapy alone in HER2-negative patients according to Checkmate 649 trial results. Conversely, systemic chemotherapy prognosis remains poor. although some patients may achieve durable response to treatment and prolonged survival in advanced GC. Recently, a first-in-class, chimeric immunoglobulin G1 monoclonal antibody (zolbetuximab) that targets and binds to claudin 18 isoform 2 (CLDN18.2) has emerged as a new target therapy in GC treatment. Global phase Ⅲ trials revealed that the addition of zolbetuximab to first-line chemotherapy prolonged OS in CLDN18.2-positive and HER2-negative GC patients. This review summarizes recent clinical trials of CLDN18.2-targeted therapy.
Selection of the Utility Function of the Historic Building, Taking into Account Energy Efficiency
Authors: Shymanska Anna , Kowalska-Koczwara Alicja , Fedorczak-Cisak Małgorzata
Published: December 2023

The energy efficiency of the building should be understood as the degree of preparation of the building to ensure the comfort of its use in accordance with its intended use with the lowest possible energy consumption of the building. The article presents an in-depth analysis of the possibility of changing the utility function of a historic building in such a way that ensures all aspects of comfort while meeting energy efficiency conditions. Combinatorics methods were used for this purpose. Four possible utility functions were proposed, including the reference state, i.e., the existing state. Five aspects of comfort were considered: thermal comfort, carbon footprint, energy efficiency, noise and vibration. For these five aspects of comfort, boundary conditions were adopted depending on the adopted building class. The selected utility function is therefore the result of comfort, energy efficiency and economic aspects. The purpose of the study was to verify whether the developed methodology for the selection of the utility function for historic buildings, based on combinatorial analyses, would allow the selection of the optimal function from the point of view of energy efficiency, user comfort and environmental impact. The methodology was tested on a historic building located in southern Poland. The new utility function for the analyzed building is to use the historic villa (or some part of it) as an Art Gallery.
Correction: Xu et al. Effects of Replacing Dietary Fish Meal by Soybean Meal Co-Fermented Using Bacillus subtilis and Enterococcus faecium on Serum Antioxidant Indices and Gut Microbiota of Crucian Carp Carassius auratus. Fishes 2022, 7, 54
Authors: Xu Qian , Yang Zheng , Chen Siyu , Zhu Wenjuan , Xiao Siyuan , Liu Jing , Wang Hongquan , Lan Shile
Published: December 2023

In the original publication [...]
Food Safety Awareness, Changes in Food Purchasing Behaviour and Attitudes towards Food Waste during COVID-19 in Türkiye
Authors: Erol Irfan , Mutuş Begüm , Ayaz Naim Deniz , Stowell Julian D. , Sırıken Belgin
Published: December 2023

(1) Background: The COVID-19 pandemic brought the key issues of food security, food safety, and food waste into sharp focus. Türkiye is in the enviable position of being among the top ten agricultural economies worldwide, with a wide diversity of food production. This survey was undertaken in order to gain insights into consumer behaviour and attitudes in Türkiye with respect to these issues. The objective was to highlight strengths and weaknesses, identify areas for improvement, and present strategies for the future. (2) Methods: This survey was carried out between April and May 2022 in 12 provinces throughout Türkiye. Face-to-face interviews were performed with 2400 participants representing a cross-section of ages, educational attainment, and socio-economic categories. The findings were evaluated statistically. (3) Results: The results provide an insight into attitudes and behaviours, both pre-COVID-19 and during the pandemic. In several ways, the pandemic enhanced knowledge and improved behaviour, leading to improvements in diet and reductions in food waste. However, worrying concerns about food safety persist. Specific attention has been given to understanding patterns of bread consumption, particularly in consideration of waste. (4) Conclusions: It is hoped that the results of this survey will increase dialogue between the components of the food sector, encourage education initiatives, and contribute to improving food safety and security and reducing food waste in Türkiye and beyond.
Opuntia Ficus-Indica Peel By-Product as a Natural Antioxidant Food Additive and Natural Anticoccidial Drug
Authors: Amrane-Abider Meriem , Imre Mirela , Herman Viorel , Debbou-Iouknane Nedjima , Saci Fairouz , Boudries Hafid , Madani Khodir , Merzouk Hafida , Ayad Abdelhanine
Published: December 2023

The present study was carried out to valorize the Opuntia ficus-indica (OFI) by-products by extracting and identifying their biochemical compounds and evaluating their antioxidant potential by in vitro activities (DPPH radical and FRAP), as well as their capacity to stabilize margarine oxidation (rancimat test). In addition, their in vitro anticoccidial effect on the destruction of Eimeria oocysts isolated from naturally infected chickens was also targeted. Microwaves and response surface methodology tools were used to extract the maximum amount of phenolic compounds (42.05 ± 0.46 GAE mg/g DW of total phenolic compounds in 90 s at 400 watts). Moreover, the effect of extraction factors was also studied. Eight phenolic compounds, including isorhamnetin, dihydrokaempferol, and kaempferol-3-O-rutinoside, were identified. The findings confirmed that OFI peel extract has strong antioxidant activities (DPPH radical, ferric reducing power). The rancimat test shows that OFI peel extract improves margarine stability by 3.2 h. Moreover, it has a notable destruction rate of Eimeria oocysts (30.06 ± 0.51%, LC50: 60.53 ± 0.38 mg/mL). The present investigation offers promise for the reuse of food waste as natural margarine additives, protection of the environment, and substitution of anticoccidial synthetic treatments.
3D-Printed Hydrogel for Diverse Applications: A Review
Authors: Agrawal Arpana , Hussain Chaudhery Mustansar
Published: December 2023

Hydrogels have emerged as a versatile and promising class of materials in the field of 3D printing, offering unique properties suitable for various applications. This review delves into the intersection of hydrogels and 3D printing, exploring current research, technological advancements, and future directions. It starts with an overview of hydrogel basics, including composition and properties, and details various hydrogel materials used in 3D printing. The review explores diverse 3D printing methods for hydrogels, discussing their advantages and limitations. It emphasizes the integration of 3D-printed hydrogels in biomedical engineering, showcasing its role in tissue engineering, regenerative medicine, and drug delivery. Beyond healthcare, it also examines their applications in the food, cosmetics, and electronics industries. Challenges like resolution limitations and scalability are addressed. The review predicts future trends in material development, printing techniques, and novel applications.
An Application of System Dynamics to Characterize Crop Production for Autonomous Indoor Farming Platforms (AIFP)
Authors: Ryu Jae Hyeon , Subah Zarin , Baek Jeonghyun
Published: December 2023

Smart farming using technology-monitored controlled environment agriculture (CEA) has recently evolved to optimize crop growth while minimizing land use and environmental impacts, especially for climate-threatened regions. This study focuses on characterizing crop production using system dynamics (SD) modeling, which is a relatively new approach in CEA settings. Using tomatoes in a hydroponic growing system, we explore an alternative food resource potentially accessible to underserved areas in rural and/or urban settings under abrupt climate variability. The designed autonomous indoor farming platforms (AIFP) are equipped with the Internet of Things (IoT) to monitor the physiological parameters, including electrical conductivity (EC), pH, and water temperature (WT) associated with plant growth. Two varieties of tomato (Solanum lycopersicum) plants were used in this study with two different nutrient inputs (N-P-K ratios of 2-1-6 and 5-5-5) to assess the nutrient application impact on yield, especially focusing on the early stages of tomato to conceptualize and parametrize SD modes. Repeated measure analysis was conducted to investigate the effects of the environmental factors (EC, pH, and WT) in response to changing plant nutrients. The results show that different nutrient compositions (N-P-K ratios) have a noticeable effect on both pH and WT (p < 0.001) as opposed to EC. The study indicates that the proposed AIFP would be a promising solution to produce other crops for indoor farming in a changing climate. We anticipate that the proposed AIFP along with SD tools will be widely adopted to promote indoor farming in changing climates, ultimately contributing to community resilience against food insecurity in disadvantaged areas for years to come.
Daily-Scale Prediction of Arctic Sea Ice Concentration Based on Recurrent Neural Network Models
Authors: Feng Juanjuan , Li Jia , Zhong Wenjie , Wu Junhui , Li Zhiqiang , Kong Lingshuai , Guo Lei
Published: December 2023

Arctic sea ice prediction is of great practical significance in facilitating Arctic route planning, optimizing fisheries management, and advancing the field of sea ice dynamics research. While various deep learning models have been developed for sea ice prediction, they predominantly operate at the seasonal or sub-seasonal scale, often focusing on localized areas, and few cater to full-region daily-scale prediction. This study introduces the use of spatiotemporal sequence data prediction models, namely, the convolutional LSTM (ConvLSTM) and predictive recurrent neural network (PredRNN), for the prediction of sea ice concentration (SIC). Our analysis reveals that, when solely utilizing SIC historical data as the input, the ConvLSTM model outperforms the PredRNN model in SIC prediction. To enhance the models’ capacity to capture spatiotemporal relationships between multiple variables, we expanded the range of input data types to form the ConvLSTM-multi and PredRNN-multi models. Experimental findings demonstrate that the prediction accuracy of the four models significantly surpasses the CMIP6 model in three prospective climate scenarios (SSP126, SSP245, and SSP585). Of the four models, the ConvLSTM-multi model excels in assimilating the influence of reanalysis data on sea ice within the sea ice edge region, thus exhibiting superior performance than the PredRNN-multi model in predicting daily Arctic SIC over the subsequent 10 days. Furthermore, sensitivity tests on various model parameters highlight the substantial impact of sea surface temperature and prediction date on the accuracy of daily sea ice prediction, and meteorological and oceanographic parameters primarily affect the prediction accuracy of the thin-ice region at the edge of the sea ice.
Target2: The Silent Bailout System That Keeps the Euro Afloat
Authors: Blake David
Published: December 2023

Target2 is the Eurozone’s cross-border payment system, which is mandatory for the settlement of euro transactions involving Eurozone central banks. It is being used to save the Eurozone from imploding. A key underlying problem is that the Eurozone does not satisfy the economic conditions for being an Optimal Currency Area, i.e., a geographical area over which a single currency and monetary policy can operate on a sustainable, long-term basis. The different business cycles in the Eurozone, combined with poor labour and capital market flexibility, mean that systematic trade surpluses and deficits will build up because inter-regional exchange rates can no longer be changed. Surplus regions need to recycle the surpluses back into deficit regions via transfers to keep the Eurozone economies in balance. But the largest surplus country—Germany—refuses to formally accept that the European Union is a ‘transfer union’. However, deficit countries, including the largest of these—Italy—are using Target2 for this purpose. Target2 has become a giant credit card for Eurozone members that import more than they export to other members, but with two differences compared with normal credit card debt: neither the debt nor the interest that accrues on the debt ever needs to be repaid. Furthermore, the size of the deficits being built up is causing citizens in deficit countries to lose confidence in their banking systems, leading them to transfer their funds to banks in surplus countries. Target2 is also being used to facilitate this capital flight. However, these are not viable long-term solutions to systemic Eurozone trade imbalances and weakening national banking systems. There are only two realistic outcomes. The first is a full fiscal and political union, with Brussels determining the levels of tax and public expenditure in each member state—which has long been the objective of Europe’s political establishment. The second outcome is that the Eurozone breaks up.
Urban Morphology, Identity, Heritage, and Reconstruction Processes in Middle East Post-War Scenarios: The Case of Mosul Old City
Authors: Chizzoniti Domenico Giuseppe , Lolli Tommaso
Published: December 2023

The theme of architectural reconstruction has gained significant prominence within the discipline of architecture, intersecting with the increasing complexity of contemporary events, especially complex socio-political scenarios including deliberate city destruction, often referred to as urbicide. Preservation strategies that safeguard the memory and values embedded in places have become imperative to protect this urban tangible and intangible heritage. This study explores the application of architectural reconstruction in the post-war context of Mosul (Iraq) dealing mainly with the selection of traces, combining a strategy based half on physical evidence and half on the reconstruction of memory devices, and intertwining them into an operative procedure hopefully supporting urban reconstruction. The study’s results indicate that architectural interventions focused on revitalizing these symbolic spaces play a pivotal role in reconstituting the inhabitants’ habits and sense of community in Mosul. The projects, including the Souq and the Great Mosque and districts, successfully address various challenges, including the harmonious fusion of tradition and modernization, the delicate balance between memory and oblivion, and the careful negotiation between reconstruction and restoration.
Adaptive Regression Analysis of Heterogeneous Data Streams via Models with Dynamic Effects
Authors: Wei Jianfeng , Yang Jian , Cheng Xuewen , Ding Jie , Li Shengquan
Published: December 2023

Streaming data sequences arise from various areas in the era of big data, and it is challenging to explore efficient online models that adapt to them. To address the potential heterogeneity, we introduce a new online estimation procedure to analyze the constantly incoming streaming datasets. The underlying model structures are assumed to be the generalized linear models with dynamic regression coefficients. Our key idea lies in introducing a vector of unknown parameters to measure the differences between batch-specific regression coefficients from adjacent data blocks. This is followed by the usage of the adaptive lasso penalization methodology to accurately select nonzero components, which indicates the existence of dynamic coefficients. We provide detailed derivations to demonstrate how our proposed method not only fits within the online updating framework in which the old estimator is recursively replaced with a new one based solely on the current individual-level samples and historical summary statistics but also adaptively avoids undesirable estimation biases coming from the potential changes in model parameters of interest. Computational issues are also discussed in detail to facilitate implementation. Its practical performance is demonstrated through both extensive simulations and a real case study. In summary, we contribute to a novel online method that efficiently adapts to streaming data environment, addresses potential heterogeneity, and mitigates estimation biases from changes in coefficients.
High Bacterial Contamination Load of Self-Service Facilities in Sakaka City, Aljouf, Saudi Arabia, with Reduced Sensitivity to Some Antimicrobials
Authors: Taha Ahmed E. , Alduraywish Abdulbaqi S. , Alanazi Ali A. , Alruwaili Abdulaziz H. , Alruwaili Abdulaziz L. , Alrais Mmdoh M. , Alyousef Abdulkareem A. , Alrais Abdullah A. , Alanazi Meshal A. , Alhudaib Sultan N. , Alazmi Bandar M.
Published: December 2023

Although self-service facilities (SSFs) have been used on a large scale worldwide, they can be easily contaminated by microorganisms from the hands of their sequential users. This research aimed to study the prevalence and antimicrobial susceptibility/resistance of bacteria contaminating SSFs in Sakaka, Aljouf, Saudi Arabia. We randomly swabbed the surfaces of 200 SSFs, then used the suitable culture media, standard microbiological methods, and the MicroScan WalkAway Microbiology System, including the identification/antimicrobial susceptibility testing-combo panels. A high SSFs’ bacterial contamination load was detected (78.00%). Ninety percent of the samples collected in the afternoon, during the maximum workload of the SSFs, yielded bacterial growth (p < 0.001 *). Most of the contaminated SSFs were supermarket payment machines, self-pumping equipment at gas stations (p = 0.004 *), online banking service machines (p = 0.026 *), and barcode scanners in supermarkets. In the antiseptic-deficient areas, 55.1% of the contaminated SSFs were detected (p = 0.008 *). Fifty percent of the contaminated SSFs were not decontaminated. The most common bacterial contaminants were Escherichia coli (70 isolates), Klebsiella pneumoniae (66 isolates), Staphylococcus epidermidis (34 isolates), methicillin-resistant Staphylococcus aureus (18 isolates), and methicillin-sensitive Staphylococcus aureus (14 isolates), representing 31.53%, 29.73%, 15.32%, 8.11%, and 6.31% of the isolates, respectively. Variable degrees of reduced sensitivity to some antimicrobials were detected among the bacterial isolates. The SSFs represent potential risks for the exchange of antimicrobial-resistant bacteria between the out-hospital environment and the hospitals through the hands of the public. As technology and science advance, there is an urgent need to deploy creative and automated techniques for decontaminating SSFs and make use of recent advancements in materials science for producing antibacterial surfaces.
RF Interconnection Design of Bump Bonding with a Dislocation Package Structure towards Electro-Optic Modulation Applications
Authors: Peng Jiahao , Wang Xiaofeng , Wang Libo , Li Yang , Liu Runhao , Deng Shiyao , Guan Heyuan , Lu Huihui
Published: December 2023

Bonding technology can be an important component of packaging for photonic chips, such as electro-optic (EO) modulators and other active function devices. In general, an EO modulator chip can achieve a broader 3 dB EO bandwidth than its packaging device, as the packaging design and structure can technically limit modulation performance. Recently, bump bonding has been shown to be a good candidate for the EO interconnection technique, which has a higher transmission bandwidth than wire bonding. In this article, we propose a design for radio frequency (RF) interconnection of bump bonding with a dislocation packaging (BBDP) structure. Through simulation calculations and analysis, the proposed BBDP structure shows a 3 dB transmission bandwidth of approximately 145 GHz, which is 52.6% better than one using optimized wire-bonding structures (95 GHz). The proposed packaging structure presents an important alternative method for ultrahigh speed optical modulation applications.
SAINT (Small Aperture Imaging Network Telescope)—A Wide-Field Telescope Complex for Detecting and Studying Optical Transients at Times from Milliseconds to Years
Authors: Beskin Grigory , Biryukov Anton , Gutaev Alexey , Karpov Sergey , Oganesyan Gor , Valyavin Gennady , Valeev Azamat , Vlasyuk Valery , Lyapsina Nadezhda , Sasyuk Vyacheslav
Published: December 2023

In this paper, we present a project of a multi-channel wide-field optical sky monitoring system with high temporal resolution—Small Aperture Imaging Network Telescope (SAINT)— mostly built from off-the-shelf components and aimed towards searching and studying optical transient phenomena on the shortest time scales. The instrument consists of twelve channels each containing 30 cm (F/1.5) GENON Max objectives mounted on separate ASA DDM100 mounts with pointing speeds up to 50 deg/s. Each channel is equipped with a 4128 × 4104 pixel Andor Balor sCMOS detector and a set of photometric griz filters and linear polarizers. At the heart of every channel is a custom-built reducer-collimator module allowing rapid switching of an effective focal length of the telescope—due to it the system is capable of operating in either wide-field survey or narrow-field follow-up modes. In the first case, the field of view of the instrument is 470 square degrees (39 sq.deg. for a single channel) and the detection limits (5σ level at 5500 Å) are 12.5, 16.5, 19, 21 with exposure times of 20 ms, 1 s, 30 s and 20 min, correspondingly. In the second, follow-up (e.g., upon detection of a transient of interest by either a real-time detection pipeline, or upon receiving an external trigger) regime, all telescopes are oriented towards the single target, and SAINT becomes an equivalent to a monolithic 1-meter telescope, with the field of view reduced to 11′ × 11′, and the exposure times decreased down to 0.6 ms (1684 frames per second). Different channels may then have different filters installed, thus allowing a detailed study—acquiring both color and polarization information—of a target object with the highest possible temporal resolution. The telescopes are located in two pavilions with sliding roofs and are controlled by a cluster of 25 computers that both govern their operation and acquire and store up to 800 terabytes of data every night, also performing its real-time processing using a dedicated fast image subtraction pipeline. Long-term storage of the data will require a petabyte class storage. The operation of SAINT will allow acquiring an unprecedented amount of data on various classes of astrophysical phenomena, from near-Earth to extragalactic ones, while its multi-channel design and the use of commercially available components allows easy expansion of its scale, and thus performance and detection capabilities.
Detecting Photovoltaic Panels in Aerial Images by Means of Characterising Colours
Authors: Marletta Daniele , Midolo Alessandro , Tramontana Emiliano
Published: December 2023

The detection of photovoltaic panels from images is an important field, as it leverages the possibility of forecasting and planning green energy production by assessing the level of energy autonomy for communities. Many existing approaches for detecting photovoltaic panels are based on machine learning; however, they require large annotated datasets and extensive training, and the results are not always accurate or explainable. This paper proposes an automatic approach that can detect photovoltaic panels conforming to a properly formed significant range of colours extracted according to the given conditions of light exposure in the analysed images. The significant range of colours was automatically formed from an annotated dataset of images, and consisted of the most frequent panel colours differing from the colours of surrounding parts. Such colours were then used to detect panels in other images by analysing panel colours and reckoning the pixel density and comparable levels of light. The results produced by our approach were more precise than others in the previous literature, as our tool accurately reveals the contours of panels notwithstanding their shape or the colours of surrounding objects and the environment.
The Influence of Giardia duodenalis on the Occurrence of Clinical Signs in Dogs
Authors: Šmit Iva , Potočnjak Dalibor , Matijatko Vesna , Torti Marin , Jović Ines , Grden Darko , Crnogaj Martina , Beck Relja
Published: December 2023

Giardia duodenalis infections are common in dogs and are mainly caused by assemblages C and D. The aim of this study was to investigate the correlation between the presence of Giardia duodenalis and different Giardia assemblages detected in symptomatic and asymptomatic dogs and the occurrence of certain clinical signs. All the dogs included (n = 82) were clinically examined, and fecal samples were examined for other parasites and Clostridium spp. Also, G. duodenalis assemblages were detected and the occurrence of certain clinical signs was assessed. A total of 42/82 (51.2%) dogs were symptomatic and had one or more gastrointestinal signs, and 40/82 (48.8%) dogs were asymptomatic. G. duodenalis was found in 25/82 (30.5%) dogs: assemblage C in 10/25 (40%) and assemblage D in 15/25 (60%). Only Cryptosporidium spp. showed a higher coinfection rate with G. duodenalis but that did not have an influence on clinical sign appearance. There was no correlation between the presence of different assemblages of G. duodenalis and the sex of the host or the duration and appearance of certain clinical signs, except the presence of mucus in feces, which was more frequent in dogs invaded with G. duodenalis assemblage C. Further research of other assemblages is needed.
Kidney trajectory charts improve GP management of patients with reduced kidney function: a randomised controlled vignette study
Authors: Guppy Michelle , Glasziou Paul , Jones Mark , Beller Elaine , Shaw Jonathan E , Barr Elizabeth , Doust Jenny
Published: December 2023

Background

The stages of chronic kidney disease (CKD) and estimated glomerular filtration rate (eGFR) reference ranges are currently determined without considering age.

Aim

To determine whether a chart that graphs age with eGFR helps GPs make better decisions about managing patients with declining eGFR.

Design & setting

A randomised controlled vignette study among Australian GPs using a percentile chart plotting the trajectory of eGFR by age.

Method

Three hundred and seventy-three GPs received two case studies of patients with declining renal function. They were randomised to receive the cases with the chart or without the chart, and asked a series of questions about how they would manage the cases.

Results

In an older female patient with stable but reduced kidney function, use of the chart was associated with GPs in the study recommending a longer follow-up period, and longer time until repeat pathology testing. In a younger male First Nations patient with normal but decreasing kidney function, use of the chart was associated with GPs in the study recommending a shorter follow-up period, shorter time to repeat pathology testing, increased management of blood pressure and lifestyle, and avoidance of nephrotoxic medications. This represents more appropriate care in both cases.

Conclusion

Having access to a chart of percentile eGFR by age was associated with more appropriate management review periods of patients with reduced kidney function, either by greater compliance with current guidelines or greater awareness of a clinically relevant kidney problem.
Conciencia ambiental en la responsabilidad social universitaria
Authors: Moreno Sánchez Victoria Emilia , Palacios Garay Jessica Paola , Nuñez Vara Fernando , Valdez Asto José Luis
Published: December 2023

La conciencia ambiental es la capacidad del individuo de reconocer la importancia de los elementos esenciales que presenta el mundo que lo rodea para conservar, cuidar y mejorar el medioambiente con conductas ambientales desde el activismo y la educación. El objetivo del estudio fue establecer la influencia de la conciencia ambiental en la responsabilidad social universitaria en estudiantes universitarios. El tipo de investigación fue básica de nivel explicativo, de diseño no experimental, transversal correlacional causal. La población estuvo conformada por 975 estudiantes de una universidad pública, la muestra fue de 276 estudiantes y el muestreo probabilístico. La confiabilidad de instrumentos a través del Alfa de Cronbach fue de .987 para el instrumento de conciencia ambiental y 0.896 para la responsabilidad social. Los resultados demostraron que la conciencia ambiental influye significativamente con 99.4% en la responsabilidad social universitaria. Se concluye que la conciencia ambiental impacta en el desarrollo de óptimas conductas proambientales responsables.
PELATIHAN PENDIDIKAN KESEHATAN GIGI PADA GURU-GURU DENGAN MEMAKAI MEDIA VIDEO TUTORIAL MENYIKAT GIGI DI MADRASAH IBTIDAIYAH
Authors: Ningrum Nining , Marah Laut Deru , Heriyanto Yonan
Published: December 2023

Perilaku masyarakat sangat dipengaruhi oleh pengetahuan akan kesehatan gigi yang masih rendah sehingga  kesadaran masyarakat akan pentinnya  menjaga dan memelihara kesehatan gigi dan mulutnya menjadi rendah pula. Data Riskesdas 2018 , hanya 2,8 %  penduduk Indonesia yang berusia lebih dari 3 tahun yang sudah menyikat gigi dengan benar , menyikat 2 kali sehari pagi sesudah makan dan malam sebelum tidur. Penyuluhan kesehatan melalui media video memiliki kelebihan dalam hal memberikan visualisasi yang baik sehingga memudahkan proses penyerapan pengetahuan. Metoda pelaksanaannya meliputi beberapa  kegiatan yaitu : memberi pelatihan kesehatan gigi dan mulut bagi guru-guru Madrasah Pesantren Persatuan Islam no.13 , melaksanakan pendampingan pada saat guru- guru  terlatih melakukan “transfer ilmu” pada siswa, melaksanakan pendampingan ketika guru -guru memberi penyuluhan materi kesehatan gigi pada siswa-siswinya, melaksanakan pendampingan ketika guru menyusun program sikat gigi masal dengan memakai media video tutorial menyikat Gigi   dan penyuluhan terjadual untuk para siswanya dan melaksanakan evaluasi .Hasil Pelatihan Kesehatan Gigi pada 10 guru mitra-1  dan  10 orang  guru mitra-2 terpilih disertai evaluasi kognitif berupa pre-postest dan evaluasi keterampilan menyikat gigi;  bimbingan sikat gigi bersama  dengan pemutaran video Tutorial menyikat gigi pada siswa madrasah Ibtidaiyah dan madrasah diniyah . Hasil pelatihan pada  guru –guru dari kedua Madrasah  cukup baik dimana terdapat peningkatan capaian rata-rata hasil nilai pre dan postest.
EDUKASI DAN SOSIALISASI PEMANFAATAN DAUN TEH HIJAU (Camellia sinensis L) DALAM MENGURANGI RESIKO PENYAKIT HATI
Authors: Riyani Ani , Kurnaen Nani
Published: December 2023

Penyakit hati dapat disebabkan oleh bahan infeksius, pulotan, radikal bebas, makanan toksis, pemakaian  obat-obatan dan senyawa kimia. Telah dilakukan penelitian tentang pengaruh tentang pengaruh ekstrak etanol daun teh hijau dalam menjaga hati mencit galur Balb/C dari induksi CCl4, dimana hasilnya ekstrak daun teh hijau dapat menjaga sel-sel hati dari kerusakan. Daun teh hijau mengandung senyawa yang berfungsi sebagai antioksidan, anti bakteri dan hepatoprotektor sehingga dapat bermanfaat dalam menjaga kesehatan hati. Pengabdian kepada masyarakat ini bertujuan untuk memberikan edukasi dan sosialisasi tentang manfaat daun teh hijau dalam melindungi  kesehatan hati kepada warga RW 05. Edukasi meliputi penjelasan tentang penyakit hati, penyebabnya dan cara penularannya serta bagaimana cara mencegahnya. Edukasi dan sosialisasi tentang manfaat daun teh hijau daun dan cara mengkonsumsinya. Evaluasi dilakukan dengan pemeriksaan tekanan darah dan kuesioner terhadap pengetahuan yang telah diberikan. Sebanyak 40 orang warga telah mengikuti pengabdian kepada masyarakat, dengan hasil sebagai berikut, usia terbanyak adalah 41-50 tahun (42,5%),  penurunan tekanan darah sebanyak 11% dari 150/91 menjadi 133/88, peningkatan prosentase pengetahuan tentang teh hijau setelah edukasi dan sosialisasi dari 55%  menjadi 69% dan peningkatan pengetahuan hati dan penyakit hati setelah edukasi dan sosialisasi dari 45% menjadi 71%. Kesimpulan dari pengabdian masyarakat ini adalah masyarakat yang ikut berpartisipasi sebanyak 40 orang dengan usia sekitar 20-83 tahun, penurunan tekanan darah warga, setelah mengkonsumsi seduhan daun teh hijau, terjadi peningkatan pengetahuan warga setelah dilaksanakan sosialisasi dan edukasi tentang teh hijau dan tara cara mengkonsumsi daun teh hijau dan peningkatan pengetahuan warga setelah dilaksanakan sosialisasi dan edukasi tentang hati dan penyakit hati.
PEMBERDAYAAN MASYARAKAT DALAM UPAYA PROGRAM KAMPUNG BERSIH DENGAN MEMANFAATKAN SAMPAH ORGANIK MENJADI PUPUK ORGANIK CAIR MEREK”PISWA”
Authors: Yati Wartini , Susanto Joko , Rojali Rojali , Lisa Desembra , Sari Prita
Published: December 2023

Permasalahan  sampah sampai saat ini menjadi  isu  yang belum terselesaikan terutama sampah organik.Kemandirian dan tidak produktif dalam pengurangan sampah,belum terpilahnya sampah anorganik dan organik menjadi pekerjaan rumah,dibarengi belum adanya rumah pengelolaan sampah organik terpadu di wilayah tersebut.Program kampung bersih,menjadi tujuan untuk penanganan sampah organik di wilayah binaan dalam pemberdayaan pengembangan kewirausahaan dengan memanfaat sampah organik menjadi pupuk organik cair merek”Piswa”.Tujuan pemberdayaan ini adalah mempraktekkan pembuatan pupuk organik cair dengan memanfaatkan sampah organik.Pertemuan advokasi antar mahasiswa,serta melakukan evaluasi terhadap kegiatan yang dilakukan. Hasil penelitianm menunjukkan bahwa unsur hara mikro Fe total 16,96 ppm,Mn total 6,26 ppm,Zn total 1,61 ppm.Sedangkan Unsur hara mikro K2O mencapai 0,16 %, dan Na+ sekitar 0,02 %.Hasil tersebut menunjukkan bahwa Pupuk Organic Cair yang dibuat mempunyai nilai jual,jika dikembangkan sampai pada tahap penjualan.Sisi kebermanfaatan dan skill yang didapat dapat dikembangkan lagi dengan membuat jenis lainnya.Sehingga pengurangan sampah organik yang ada di wilayah binaan bisa ditangani dengan memanfaatkan sampah organik menjadi nilai ekonomi.
EDUKASI KESEHATAN GINJAL DAN PEMERIKSAAN KREATININ URIN PADA IBU-IBU DI KELURAHAN GLUGUR DARAT 2 MEDAN
Authors: Lubis Nita Andriani , Nasution Gabriella Septiani , Ningsih Sri Widia
Published: December 2023

Kegiatan ini merupakan implementasi dari penelitian yang kami lakukan sebelumnya. WHO mencatat prevalensi gagal ginjal kronik di seluruh dunia sebesar 8 – 16%. Kerusakan ginjal akan menyebabkan peningkatan kreatinin urin Pengabdian kepada masyarakat (Pengmas) Prodi Teknologi Laboratorium Medis Poltekkes Kemenkes Medan dilakukan untuk memberikan pelayanan kesehatan yang diimplementasikan dalam bentuk pengabdian masyarakat. Metode pelaksanaan pengabdian yang diberikan berupa edukasi kesehatan untuk meningkatkan pengetahuan ibu-ibu mengenai kesehatan ginjal dan pemeriksaan kreatinin urin. Khalayak sasaran pada pengabdian masyarakat ini adalah ibu ibu di Lingkungan III Kelurahan Glugur Darat 2 Kecamatan Medan Timur berjumlah 40 orang. Tingkat pengetahuan , sikap dan tindakan responden sebelum (pre) intervensi dan setelah (post) intervensi edukasi kesehatan ginjal mengalami peningkatan. Nilai kreatinin urin 24 jam yang diukur pada 40 orang responden, diperoleh kelompok < normal sebanyak 1 orang (3%) dengan status IMT kurus, kelompok normal sebnyak 27 orang (68%) dengan status IMT normal, dan > normal sebanyak 12 orang (30%) dengan rincian 7 orang dengan status IMT berat badan lebih dan 5 orang dengan status IMT obesitas. Hasil uji statistik yang dilakukan menggunakan uji t nilai IMT dan kreatinin urin 24 jam diperoleh nilai yang signifikan (p<0.05). Hal ini menunjukkan bahwa terdapat peningkatan pengetahuan, sikap dan tindakan responden sebelum dan sesudah edukasi kesehatan ginjal, dengan nilai IMT dan kadar kreatinin urin 24 jam yang berbanding lurus.
PENINGKATAN PENGETAHUAN KADER POSYANDU DALAM PENERAPAN TEKNIK KONSERVASI ENERGI UNTUK MENINGKATKAN KUALITAS HIDUP KLIEN TUBERKULOSIS PARU
Authors: Sri Ningsih Ningning , Ritianingsih Nieniek , Nurhayati Farial
Published: December 2023

Penyakit Tuberkulosis Paru merupakan penyakit infeksi kronis dan bersifat berulang yang menyerang paru, disebabkan oleh Mycobacterium tuberculosis. Penderita tuberkulosis akan mengalami gangguan pertukaran gas, jalan nafas tidak efektif, perubahan pola nafas,  kekurangan nutrsi, dan perasaan takut. Dengan kondisi tersebut menyebabkan  kualitas hidup penderita tuberkulosis akan menurun. Penatalaksanaan untuk meningkatkan kualitas hidup klien tuberculosis salah satunya dengan teknik konservasi energi. Teknik ini berguna untuk menghemat energi pada saat klien melakukan aktivitas sehari hari, dengan menurunkan dispnea dan meningkatkan kemampuan fungsional dan sosial klien. Tujuan kegitan ini adalah untuk meningkatkan pengetahuan kader tentang Teknik konservasi energi dan kader dapat mendeseminasikan pada klien tuberculosis sehingga kualitas hidup klien tuberculosis dapat meningkat. Metode kegiatan ini dilaksanakan dengan metode pengajaran dengan ceramah dan praktek tentang teknik konservasi energi. Hasil kegiatan pengetahuan kader pada mitra I pada pre dan II menunjukan terdapat pengaruh pelatihan terhadap peningkatan pengetahuan kader kesehatan baik pada mitra I maupun pada mitra II (P=0,00) dan terdapat pengaruh penerapan teknik konservasi energi terhadap kualitas hidup klien tuberculosis pada mitra I maupun mitra II (P=0,00). Kesimpulan terdapat peningkatan pengetahuan kader tentang penyakit tuberculosis dan teknik konservasi sehingga kader dapat melaksanakan dan mendampingi klien tuberculosis. Dan Pemberian tenik konservasi energi pada klien tuberculosis menunjukan peningkatan kulitas hidup menjadi kategori baik. Disarankan Kader melanjutkan mendampingi dan mengawasi penerapan teknik konservasi energi secara rutin di wilayahnya.
UPAYA MENURUNKAN STRES DAN MENINGKATKAN EFIKASI DIRI ORANGTUA DALAM MERAWAT ANAK RETARDASAI MELALUI PEER SUPPORT GROUP
Authors: Sri Ningsih Ningning , Yuliastuti Yuliastuti , Pursitasari Ita
Published: December 2023

Kegiatan merawat dan  membesarkan anak dengan retardasi mental merupakan pengalaman yang luar biasa dan sangat emosional serta dapat menimbulkan banyak kesulitan bagi orang tua. Perawatan jangka panjang bahkan mungkin seumur hidup akan  dapat menyebabkan stress dan seringkali mempengaruhi fungsi keluarga secara keseluruhan. Stress pada orang tua sangat berpengaruh pada pola pengasuhan dan kemampuannya dalam mendidik anak dengan retardasi mental. Anak yang dibesarkan dengan tekanan akan berpengaruh terhadap perkembangannya. Orang tua yang tidak percaya diri dalam mengasuh anak karena faktor emosional, tidak asertif, tidak peduli pada anak dan tidak mampu untuk memperlakukan anak dengan tepat. Parenting Self Efficacy (PSE) merupakan salah satu cara mengukur kemampuan orang tua dalam membesarkan anak. Self efficacy dapat berpengaruh pada seseorang ketika menghadapi stres atau situasi yang sulit serta berdampak pada perilaku orang tua dalam membesarkan dan mencintai anaknya. Satu bentuk dukungan yang dapat dilakukan adalah dengan cara Peer support group (PSG).  Peer support group (PSG) merupakan  kumpulan suatu kelompok sejenis yang melakukan kegiatan dengan tujuan untuk meningkatkan koping, memberikan dukungan sosial, saling berbagi pengalaman, mengurangi ketakutan dan kekhawatiran.  Hasil kegiatan didapatkan menunjukan ada penurunan stress pada orangtua dan peningkatan PSE dimana tingkat stress sebelum intervensi sebesar 44 dengan kategori stress tinggi dan setelah intervensi mengalami penurunan 68.2 dengan kategori stress rendah.  Dan Parenting Self Effikasi sebelum intervensi sebesar 64.1 katagori rendah bahwa orangtua kurang mampu merawat anak dan setelah intervensi sebesar 41.6 dengan kategori tinggi bahwa meningkatnya kemampuan orangtua dalam merawat anak dengan baik. Rekomendasi staf guru Sekolah Luar Biasa (SLB) untuk memfasilitasi kegiatan Peer Support Group dan terlibat langsung pada kegiatan tersebut.
Optimal CBDC design for Ukraine through the lens of privacy and security
Authors: Hudima Tetіana , Kamyshanskyi Vladyslav , Dmytrenko Tetіana , Shmyhov Mykhailo
Published: December 2023

The growing popularity of cryptocurrencies has put on the agenda the need to develop an alternative and more regulated digital currency design, including a central bank digital currency (CBDC). The objective of the study is to formulate proposals for the development of the optimal design of the CBDC of Ukraine. The study is based on a review of the literature on digital currencies, cryptocurrencies and legislation on personal data protection, payment security and financial supervision. The implementation of the CBDC in Ukraine is associated with numerous technical and legal risks, including: privacy and data security risks; complications of financial monitoring; contradictions with national and international legislation; banks disintermediation risks.

To prevent these risks, a CBDC design is proposed that is compatible with national and international legislation, ensures data privacy and security, facilitates financial tracking, and reduces the risks of disintermediation.

The development of the CBDC in Ukraine could have a significant impact on the country's financial system. However, it is essential that the design of the CBDC is carefully considered to mitigate potential risks.
MEMASYARAKATKAN PANCASILA MELALUI ETOS KERJA, INTEGRITAS, DAN KEBIJAKAN ORGANISASI YANG BERKEADILAN
Authors: Liswandi Liswandi , Mapuasari Supeni Anggraeni
Published: December 2023

Understanding Pancasila and applying it to everyday life can make life more calm and peaceful in society. Pancasila covers various aspects of life, both interactions with fellow humans and with God. In the current conditions, the issue of integrity can reduce the quality of Indonesian human resources. Therefore, the introduction of Pancasila values to the community can be used as an option to remind the values and norms of life that are in harmony with the community. Pancasila value introduction activity is carried out online in the form of webinars and discussions. Participated by hundreds of participants consisting of students from various campuses, the Pancasila dialogue can be one of the concrete steps to strengthen the integrity of today's young generation.

Keywords: Pancasila Values, Integrity, Work Ethic