bluuebunny/crossref_metadata_2025 huggingface dataset:
STEM Education and Problem-Solving in Space Science: A Case Study with CanSat
Authors: Contente José , Galvão Cecília
Published: February 2022

Research has shown that hands-on projects promote stem education, namely, via problem-solving. CanSat, literally 'satellite in a can', is a stem educational project promoted by the European Space Agency. This paper addresses this issue by researching this STEM project, which demonstrates how problem-solving can be achieved in secondary-level students within the framework of the CanSat. We use qualitative techniques of data collection and analysis. The results showed that students use sophisticated thinking strategies to process information within this interdisciplinary project: (a) cognitive testing, cognitive organization, cognitive regulation, and monitoring, in addition to computer language and physical–mathematical calculations, are cognitive and metacognitive behavior strategies revealed in the CanSat; (b) problem-solving was suggested as a specific model, where students’ higher cognitive and metacognitive ordering processes deepen in project development; (c) computational, lateral, or divergent and convergent thinking were detected as thinking types of students associated with and mobilized in the course of problem-solving, The findings of this research have practical implications for STEM education in space science. Hands-on projects using problem-solving are an essential strategy to promote STEM education. Additionally, they are a starting point to promote meaningful learning and new thinking types.
Investigating Transfer Learning in Graph Neural Networks
Authors: Kooverjee Nishai , James Steven , Van Zyl Terence
Published: February 2022

Graph neural networks (GNNs) build on the success of deep learning models by extending them for use in graph spaces. Transfer learning has proven extremely successful for traditional deep learning problems: resulting in faster training and improved performance. Despite the increasing interest in GNNs and their use cases, there is little research on their transferability. This research demonstrates that transfer learning is effective with GNNs, and describes how source tasks and the choice of GNN impact the ability to learn generalisable knowledge. We perform experiments using real-world and synthetic data within the contexts of node classification and graph classification. To this end, we also provide a general methodology for transfer learning experimentation and present a novel algorithm for generating synthetic graph classification tasks. We compare the performance of GCN, GraphSAGE and GIN across both the synthetic and real-world datasets. Our results demonstrate empirically that GNNs with inductive operations yield statistically significantly improved transfer. Further we show that similarity in community structure between source and target tasks support statistically significant improvements in transfer over and above the use of only the node attributes.
Treatise On Analytic Optimal Spacecraft Guidance And Control
Authors: Sands Timothy
Published: February 2022

Autonomous navigation of spacecraft necessitates innovative technologies, methods, and algorithms, particularly when orbiting in proximity of other space objects. Optimization methods are useful for autonomous spacecraft navigation, guidance, and control, but their performance is hampered by noisy multi-sensor technologies and poorly modeled system equations, and real-time on-board utilization is generally computationally burdensome. Some proposed methods use noisy sensor data to learn the optimal guidance and control solutions real-time (online), where non-iterative instantiations are preferred to reduce computational burdens. This study aims to highlight efficacy and limitations of several common methods for optimizing guidance and control while proposing a few more, where all methods are applied to the full, nonlinear, coupled equations of motion including cross-products of motion from the transport theorem. Five disparate types of optimum guidance and control algorithms are presented and compared to a classical benchmark. Comparative analysis is based on tracking errors (both states and rates), fuel usage, and computational burden. Real-time optimalization with singular switching plus nonlinear transport theorem decoupling proves superior by matching open-loop solutions to the constrained optimization problem (in terms of state and rate errors and fuel usage), while robustness is validated in the utilization of mixed, noisy state and rate sensors and uniformly varying mass and mass moments of inertia. State tracking errors are reduced one-hundred ten percent. Rate tracking errors are reduced one-hundred thirteen percent. Control utilization (e.g., fuel) is reduced eighty four percent, while computational burden in reduced ten percent simultaneously.
Potent Activity of High Concentration Ozone Therapy Against Antibiotic-Resistant Bacteria
Authors: Rangel Karyne , Cabral Fellipe O , Lechuga Guilherme Curty , Carvalho João P.R.S. , Villas-Bôas Maria H.S. , Midlej Vitor , De-Simone Salvatore Giovanni
Published: February 2022

(1) Background: Health Care-Associated Infections (HAIs)are a significant public health problem worldwide favoring multidrug-resistant (MDR) microorganisms. The SARS-CoV-2 infection had a negative association with the increase in antimicrobial resistance, and the ESKAPE group had the most significant impact on HAIs. The study aimed to evaluate the bactericidal effect of high concentration O3 gas on some reference and ESKAPE bacteria. (2) Material and Methods: Four standard strains and four clinical or environmental MDR strains were exposed to high ozone doses at different concentrations and times. Bacterial inactivation (growth and cultivability) was investigated using colony counts and resazurin as a metabolic indicator. Scanning electron microscopy (SEM) was performed. (3) Results: The culture exposure to a high level of O3 inhibited the growth of all bacterial strains tested with a statistically significant reduction in colony count compared to the control group. The cell viability of S. aureus (MRSA) (99,6%) and P. aeruginosa (XDR) (29,2%) was reduced considerably, and SEM showed damage on bacteria after O3 treatment (4) Conclusion: High doses of ozone were able to interfere in the growth of all strains studied, evidencing that ozone-based decontamination approaches may represent the future of hospital cleaning methods.
Mapping Spatiotemporal Heterogeneity in Tumour Progression by Integrating High-Throughput Imaging and Omics Analysis
Authors: Patkulkar Pooja Annasaheb , Subbalakshmi Ayalur Raghu , Jolly Mohit Kumar , Sinharay Sanhita
Published: February 2022

Intratumoral heterogeneity associates with more aggressive disease progression and worse patient outcomes. Understanding the reasons enabling the emergence of such heterogeneity remains incomplete, which restricts our ability to manage it from a therapeutic perspective. Technological advancements such as high-throughput molecular imaging, single-cell omics and spatial transcriptomics now allow recording the patterns of spatiotemporal heterogeneity in a longitudinal manner, thus offering insights into the multi-scale dynamics of its evolution. Here, we review latest technological trends and biological insights from molecular diagnostics as well as spatial transcriptomics, both of which have witnessed a burgeoning growth in recent past in terms of mapping heterogeneity within tumor cell types as well as stromal constitution. We also discuss ongoing challenges, indicating possible ways to integrate insights across these methods to have a systems-level spatiotemporal map of heterogeneity in each tumor, and a more systematic investigation of implications of heterogeneity for the patient outcomes.
A Nonlinear Radio-photon Conversion Device
Authors: Vinogradova Irina L. , Gizatulin Azat R. , Meshkov Ivan K. , Bourdine Anton V. , Tiwari Manish
Published: February 2022

The article analyzes existing materials and structures with quadratic-nonlinear optical properties that can be used to generate a difference frequency in the terahertz and sub-terahertz frequency ranges. The principle of constructing a nonlinear optical-radio converter, based on an optical focon (a focusing cone), is proposed. Based on the assumption that this focon can be implemented from the metal-organic framework (MOF), we propose a technique for modeling its parameters. The mathematical model of the process of propagation and nonlinear interaction of waves inside the focon is based on a simplification of the nonlinear wave equation. Within the framework of the developed model, the following parameters are approximately determined: the 3D gradient of the linear refractive index and the function determining the geometric profile of the focon, which provide a few-mode-based generation of the difference frequency.
Natural Language Processing Of Helpline Chat Data Before And During The Pandemic Revealed Significant Decrease In Self-image Appreciation And Changes In Other Traits
Authors: Raveau Maria Paz , Goñi Julian , Rodriguez José , Paiva Isidora , Barriga Fernanda , Hermosilla Maria Paz , Fuentes Claudio , Eyheramendy Susana
Published: February 2022

During the last two years the COVID-19 pandemic has affected the world population in several ways. An important increase in mental health problems is a consequence of this pandemic that is ubiquitous worldwide. In this work we study the effect of the pandemic on the mental health of a population of teenagers and youth based on the analysis of natural language processing, machine learning algorithms and expert knowledge. The data analysed was obtained from a chat helpline called Safe time from theIt Get’s Better Foundation in Chile. The data consists of 10,986 conversations gathered from 2018 until 2020 between volunteers from the foundation and users of the platform. We compared the conversationsbefore and during the pandemic in terms of their thematic content. Our analysis found: a significantdecrease in self-image appreciation during the pandemic; a significant decrease in the quality of personalrelationships during the pandemic, and a significant increase of performance appreciation.
Efficiency Of Positron-emission Tomography With 18F-DOPA For Visualization Of Dophaminergency System Of Brain
Authors: Sadovsky Michael , Abramov Vladislav , Tutsenko Ksenia , Khoroshavina Alina , Tunik Mariia , Anuchina Tatiana , Malchik Natalia , Saveleeva Anastasia , Pokhabov Dmitry
Published: February 2022

Positron-emission tomography is powerful but costly tool for various medical investigations. In particular, it is used in Parkinson’s disease and essential tremor diagnostics. However, yet there is no standardized figures of the references, for it. We examined the PET efficiency for the analysis of development and degradation of dophaminergic neurons in Parkinson’s disease. The informative indices are determined from the observed PET data. Also, high efficiency of PET for Parkinson’s disease as approved.
PENYIMPANGAN BAHASA PUISI DALAM SASTRA SIBER
Authors: Solihati Nani
Published: January 2022

AbstrakPenelitian ini bertujuan untuk mengetahui penyimpangan bahasa puisi dalam sastra siber. Untuk mengetahui hal tersebut, maka penelitian ini menggunakan metode deskriptif kualitatif. Hasil penelitian ini menunjukkan bahwa lima puisi yang terdapat dalam sastra siber dengan data sampelyang diambil dari laman sastradigital.com melakukan penyimpangan bahasa. Kelima puisi itu ialah puisi Kidung Rindu Bagi Perempuanku karya Alif Raung Firdaus melakukan penyimpangan sintaksis, penyimpangan historis, dan penyimpangan leksikal, puisi Aek Sarulla karya Mangasi Sihombing melakukan penyimpangan dialek dan penyimpangan historis, puisi mimpi dari Milimeter Jarak Sepi karya Ujianto Sadewamelakukan penyimpangan sintaksis dan penyimpangan semantis,puisi Bukan Kopi Hongaria karya Cecep Samsul Harimelakukan penyimpangan semantis dan penyimpangan dialek, dan puisi Di Jembatan Pasupati karya Fajar M. Fitrah melakukan penyimpangan sintaksis, penyimpangan grafologis, penyimpangan register, dan penyimpangan dialek.
KURIKULUM 2013 DALAM PERSEPSI DAN INTERPRETASI GURU-GURU BAHASA INGGRIS
Authors: Ahmad Djuwariah , Mardiana Mardiana
Published: January 2022

AbstrakMakalah ini bertujuan mendeskripsikan secara analitik persepsi dan interpretasi guru-guru bahasa Inggris terhadap Kurikulum 2013 berdasarkan hasil penelitian pada 4 SMA target implementasi di Kota Makassar. Penelitian ini menggunakan metode deskriptif analitik dengan pendekatan fenomenologi dalam paradigma kualitatif yang melibatkan 11 guru bahasa Inggris di Kelas X. Hasil penelitian menunjukkan bahwa sejalan dengan pengetahuan dan sistem kepercayaan yang dibangun guru terhadap perubahan, persepsi mereka terhadap pembelajaran bahasa Inggris dalam Kurikulum 2013 berada pada dua kutub; positif (berdampak pada transformasi dari pandangan tradisional pembelajaran menuju dimensi pedagogik modern) dan negatif yang menganggap bahwa perubahan hanya pada tingkat konseptual dengan efek yangsama pada kurikulum sebelumnya. Interpretasi guru cenderung benar dan menyeluruh pada konsep-konsep umum Kurikulum 2013 namun parsial terhadap konsep-konsep aplikatif sesuai dengan tingkat pemahaman, pengetahuan prosedural dan kenyamanan yang diperoleh dari aplikasi yang ditawarkan oleh elemen kurikulum yang berubah.
PEMBELAJARAN BERBAGAI JENIS TEKS BERBAHASAINGGRIS (ENGLISH GENRES) MELALUI OBSERVATIONAL LEARNING IMPLEMENTASI DAN PERMASALAHAN
Authors: Lasito Lasito
Published: January 2022

AbstrakPenelitian ini membahas tentang pelaksanaan pembelajaran melalui pengamatan (observational learning) dalam pengajaran berbagai jenis teks dalam bahasa Inggris (English genres) yang dilakukan di salah satu sekolah menengah atas di Jakarta. Menggunakan metode ethnografi melalui pengamatan selama satu semester, penelitian ini menunjukkan berbagai masalah penting yang dihadapi oleh guru dan siswa dalam usahanya menerapkan pembelajaran berbasis pengamatan. Pertama, keterbatasan teks yang dimiliki guru yang dijadikan sebagai model. Kedua kurangnya paparan terhadap teks yang dijadikan model menyebabkan siswa tidak memiliki informasi yang kaya akan variasi teks sejenis. Ketiga adanya penolakan siswa terhadapmetode observational learning. Siswa lebih nyaman dengan guru menerangkan dan memberikan latihan (teacher-centered) dibandingkan siswa sendiri harus mengamati danbereksplorasi dengan teks.
CODE SWITCHING IN “HALUSTIK” MOVIE BY NIA DINATA, LUCKY KUSWANDI, AND ANDRI CHUNG
Authors: Febriyanti Rina Husnaini , Sundari Hanna
Published: January 2022

Code-switching (CS) nowadays has been used by youth as a daily language among them and reflected in the “Halustik” movie. The aims of the research are to find out the category of CS spoken by the speakers and to explore their communication intentions to switch from one code to another in the movie which depicts urban life among young people. In the movie, the casts speak and communicate in four languages (Indonesian, English, Javanese, and Sundanese). Qualitative research data were collected by identifying the CS utterances from words, phrases, clauses, and sentences spoken by the main casts/characters in the movie. Next, the data were categorized, selected based on the categories of CS, and classified based on communicative intentions. The findings show that intra-sentential CS (60%) was the most used category of CS, followed by tag CS (4%), and inter-sentential CS (36%). Concerning the communicative intentions by the speakers, they alternate the language into another language since they are intended to talking about a certain topic (60%), quoting someone's words (11%), feeling empathy for something (expressing solidarity) (4%), providing interjection (4%), giving repetition for clarification (7%), clarifying the content of speech to the interlocutor (9%), and expressing a group identity (4%).
TINDAK TUTUR EKSPRESIF PADA NASKAH DRAMA AYAHKU PULANG KARYA USMAR ISMAIL
Authors: Yunita Trisnawati  , An Nisa Alfi Khoiru , Pangesti Fida
Published: January 2022

Penelitian ini memiliki tujuan untuk mendeskripsikan bentuk dari tindak tutur ekspresif yang ada pada setiap tokoh dalam pementasan drama. Penelitian ini termasuk ke dalam jenis penelitian kualitatif dengan menggunakan pendekatan deskriptif. Sumber data yang digunakan adalah tuturan yang ada pada tokoh dalam pementasan drama yang berjudul Ayahku Pulang yang dituliskan oleh Usmar Ismail yang dipentaskan oleh Teater Tuang. Data yang digunakan adalah tuturan dari tokoh yang sesuai dengan teori tindak tutur ekspresif. Teknik pengumpulan data dilakukan adalah dengan melakukan transkripsi pada video pementasan drama yang kemudian dilakukan pengelompokkan sesusai dengan indikator yang telah disiapkan, yang kemudian data tersebut dianalisis dengan bentuk deksriptif. Hasil penelitian ditemukan bahwa tindak tutur ekspresif dalam pementasan drama ditemukan 10 jenis yaitu: (1) tindak tutur permintaan maaf, (2) tindak tutur mengancam, (3) tindak tutur menyalahkan, (4) tindak tutur kesedihan (5) tindak tutur menyetujui, (6) tindak tutur marah, (7) tindak tutur kesenangan, (8) tindak tutur malu, (9) tindak tutur terkejut, dan (10) tindak tutur heran. Dan Strategi tindak tutur ekspresif ditemukan 1) Strategi bertutur terus terang tanpa basa-basi, 2) Strategi berterus terang dengan basa-basi kesantunan negatif, 3) Strategi berterus terang dengan basa-basi kesantunan positif.
THE CONSTRUCTION OF SOCIAL VALUES IN THE ORAL LITERATURE TRADITION “OLO” LANGGUDU MBOJO-BIMA
Authors: Siti Rahmatillah  , Munjiah Ma’rifatul
Published: January 2022

This research aims to explain the meaning and social values contained in Olo's oral literary traditional. This research is a type of qualitative descriptive research, and includes field research. The data collection uses closed interview techniques.The validity of the data using resource triangulation, data analysis using the techniques of data collection, selection and reduction, presentation, analysis, data crosscheck and drawing conclusions. The results of this research are that Olo is an oral literature sing using bamboo gongs and flutes as accompanying traditional musical instruments. The social values in it contain the social values of love, mutual cooperation and solidarity in the social life. The social value of love is in the form of feelings of mutual love between a man and woman in the bonds of marriage, and the value of mutual cooperation where there is unity in working together to achieve common goals in the implementation of Olo literary tradition. The social value of solidarity in social life is the presence of fraternity, brotherhood and social relations in the life of society.
GAYA BAHASA KOMUNIKASI DAKWAH DALAM CERAMAH SYEKH SULAIMAN BIN SALIMULLAH AR RUHAILY
Authors: Nurlaela Lia Fatra , Boeriswati Endry , Tajuddin Shafruddin
Published: January 2022

The purpose of this research is to broaden the understanding of the study of language analysis used in da'wah communication, to provide an overview and knowledge of forms of da'wah communication language that can be applied in everyday life and can be used as an example of qualitative research, especially content analysis. This study uses a content analysis method with a qualitative approach. The data collection technique is done by content analysis. The results showed that the form of da'wah communication style in terms of the End aspect in the lectures delivered by Syekh Sulaiman bin Salimullah Ar Ruhaily found as many as 26 utterances. The form of da'wah communication style in terms of the Act Sequences aspect was found to be 44 utterances. The form of da'wah communication style in terms of genre aspects was found as many as 29 utterances
STRATEGI PEMBERITAAN MEDIA ONLINE INDONESIA DALAM KASUS DEMONSTRASI RUU HIP (ANALISIS WACANA KRITIS THEO VAN LEEUWEEN)
Authors: HY Mclean
Published: January 2022

This research aimedto describe the different points of view among the Indonesian national online media, namely Detiknews.com, Kompas.com, CNN Indonesia and Tempo.com and to describe the tendency of the online media's attitudes in constructing the Demonstration case of the RUU HIP. The exclusion strategy is used to see how actors are excluded or hidden in the news text. This exclusion and inclusion strategy looks at how the forms of language usage are used to recapture the meaning to the public. The data of this research were found from reporting on the demonstration case of the RUU HIP in July 2020 in online media Detiknews.com, Kompas.com, Tempo.com and CNN Indonesia during 15-16 July 2020. This research used a qualitative descriptive method with a critical discourse analysis by Theo Van Leeuwen in order to describe how events and actors are portrayed in the news. The results showed that the form of Leeuwen's exclusion theory found in four news reports in online media was that Detiknews.com, Kompas.com, and CNN Indonesia in the news about the demonstration of the RUU HIP tended to use an inclusion strategy while, Tempo.com was more towards exclusion
THE USE OF SURVEY APPLICATION TO CREATE LEARNING MODULES IN THE PANDEMIC ERA
Authors: Fransori Arinah , Irwansyah Nur
Published: January 2022

Effective learning needs to be supported by adequate facilities and infrastructure that are approved in finding relevant references and materials. In the field, learning is quite difficult in the learning process because of limited referrals/material. Therefore, it is necessary to design a module that is by following the syllabus (RPS) that helps students learn independently. The purpose of the research is to find the needs and desires that are expected in the course modules in linguistic/literature research methods. The research method used was conducting a survey using questionnaires and conducting interviews. The questionnaire analyzes the needs of students and lecturers who are then analyzed by identifying based on their needs. The questionnaire for needs analysis is published with SurveyMonkey media application to facilitate the process of filling out the questionnaire. The results of the interview activities will be described qualitatively based on field observations. The subjects of the study were 100 students in the 6th semester and three lecturers who were lecturers parallel to this course. The results of this study consisted of an analysis of student needs and the views of the lecturers regarding the design content of the module, which contained; dimension of content, learning
DEVELOPMENT OF ANIMATION VIDEO LEARNING MEDIA FOR URBAN DRAINAGE COURSES IN BUILDING ENGINEERING EDUCATION
Authors: Huda Muhamad Arin Fatkhul , Maulana Arris
Published: January 2022

This study aims to obtain a video-based learning media animation development on Urban Drainage course using Adobe After Effect in Education of Building Engineering, Faculty of Engineering, State University of Jakarta. The research implementation time is April to August 2020. The development model used in this study is 4D model by Thiagarajan, which consist of define phase, design phase, development phase, and disseminate phase. The instrument used in this research was a questionnaire for need analysis, product feasibility test by experts, and product users. The result of research and product development is an animation video consisting of 4 video materials used for one semester. The results of validation by material expert get an average percentage 80% and included in feasible category. The results of validation by media expert get an average percentage 92,5% and included in very feasible category. The product assessment results by students as product users get a percentage 88,9% and included in the excellent category.
ANALYSIS OF DAMAGE LEVEL AND COST ESTIMATION OF THE SAMUDRAJAYA 04 BEKASI STATE ELEMENTARY SCHOOL BUILDING
Authors: Anisah Anisah , Lenggogeni Lenggogeni , Agustina Sri Langsih
Published: January 2022

This study aims to determine the level of damage to the school building using a benchmark assessment of the level of damage by DG Pauddikdasmen Kemendikbud in 2021 and investigate the building component repair-cost estimates using Works Unit Price Analysis (AHSP). The research population is a public elementary school in Samudrajaya Village with a sample building SDN Samudrajaya 04 Bekasi as the object of research. The method used in this research is a descriptive research method with a quantitative approach. The data collection technique was carried out through observation, documentation, and unstructured interviews. The results showed that the level of damage to the SDN Samudrajaya 04 Bekasi building in building one was slightly damaged, with the highest component of damage found in the wall component with brick wall sub-components or partition 8.2% glass, doors, and frames were not damaged. While the level of damage to building two was heavily damaged, with the highest component damage found in the wall components of the sub-components of brick or partition walls by 15%, glass 90.3%, doors 88.6%, and frames 96%. The results of the analysis of the estimated repair costs on the components that experienced the most serious damage based on the volume of damage were in building one of Rp. 30,522,168,48 and in building 2 Rp. 204,070,178.35, the total repair cost is Rp. 234,592,346.83 or can be rounded up to Rp. 234,593,000.
COMPARATIVE STUDY OF RIGID PAVEMENT PLANNING USING BINA MARGA 2017 AND AASHTO 1993 METHODS
Authors: Firgiansyah Egi , Prihantono Prihantono , Daryati Daryati
Published: January 2022

This study was conducted to determine what factors influence the differences in the results of the Bina Marga 2017 method and the AASHTO 1993 method and determine which planning results are more efficient to be applied to Letjen S. Parman Street. The research method used is a comparative method, using the existing data and the latest data from surveys. As a result of analyzing a rigid road plan with a planned age of 40 years, the Bina Marga 2017 method obtained a concrete slab with a thickness of 305 mm, and the AASHTO 1993 method obtained a concrete slab with a thickness of 280 mm. Further differences in results can be seen in the level of traffic load during the service life, the diameter of the dowels, the spacing of the tie bars, and the minimum design height of the subgrade embankment. The differences in the results of these plans are caused by two main factors, namely the factor of using the cumulative traffic growth value (R) in the Bina Marga 2017 method and the direct use of the subgrade CBR value in the AASHTO 1993 method. Based on the data that has been obtained, it is concluded that the 1993 AASHTO method provides more efficient results to be applied with considerations in terms of smaller plate dimensions and fewer connections and reinforcement requirements. Which when calculating the work cost, the AASHTO 1993 methods results give a smaller number of work volumes, so it has the possibility to provide a more economical work cost than the Bina Marga 2017 methods results.
ASSESSMENT OF E-PROCUREMENT SUBJECTS' MISSTEPS FOR CONSTRUCTION AND CONSULTANCY SERVICES THROUGHOUT THE SURABAYA CITY AREA AS AN EDUCATIONAL ADJUNCT FOR PROJECT TENDER COURSES
Authors: Adistana Gde Agus Yudha Prawira , HS Mas Suryanto , Mahardi Purwo , Sofianto Mochamad Firmansyah
Published: January 2022

From the government's perspective, an electronic tender or e-tendering system in the procurement of goods and services in Indonesia is a platform to acknowledge good governance and public services since it enhances cost efficiency, effectiveness, shorter turnaround periods, delivers excellent public monitoring, fosters competitiveness, and increases government accountability. Nevertheless, numerous tenders have managed to fail during the implementation of e-tendering for construction works. The purpose of this study is to identify the factors that contribute to tender failures throughout the Surabaya City area. The factors that contributed to the tender's failure were identified from the results of the 220 construction tenders stated on the LPSE website. Descriptive statistical analysis was used to obtain factors that cause e-tender failures from the data obtained. Administrative, technical, price, and qualification criteria are the most dominant four failure criteria. The most apparent cause for auction failure is the provider's inability to attach references to previous projects.
A Review of Orthopaedic Resident Case Logs to Identify Fluctuations in Exposure to Adult Orthopaedic Procedures
Authors: Levidy Michael F. , Dobitsch Andrew , Luis Justin , Fano Adam N. , Para Ashok , Vosbikian Michael , Beebe Kathleen , Kaushal Neil
Published: February 2022

Introduction:

Orthopaedic surgery resident case exposure is an important component of surgical training and is monitored by the Accreditation Council for Graduate Medical Education (ACGME) to ensure resident readiness for graduation. The purpose of this study was to investigate trends in exposure to adult orthopaedic surgical procedures and analyze the impact of the 2013 update in ACGME case logging expectations.

Methods:

A retrospective review of ACGME case log data was conducted for adult orthopaedic procedures performed by graduating orthopaedic surgery residents from 2012 to 2020. Trends in the number of cases logged and the case share by anatomical location were investigated. Linear regression analysis was performed to analyze changes in case number over the 9-year period.

Results:

For all surgical categories, there was stability in the average case number per resident from 2012 to 2013, followed by a precipitous decrease from 2013 to 2014. From 2014 to 2020, there has been a gradual increase in case number for all categories except “other musculoskeletal (MSK),” resulting in a total 46% recovery since the 2014 decline. Concomitant with the decline, there was a relative increase in pelvis/hip and femur/knee procedures and decrease in shoulder, other MSK, and spine procedures. From 2014 to 2020, shoulder, humerus/elbow, pelvis/hip, leg/ankle, foot/toes, and spine cases have gradually accounted for a larger proportion of total cases while femur/knee and “other MSK” cases have accounted for less.

Conclusions:

The 2013 update in ACGME case logging expectations was associated with a significant decrease in case number. This is likely a reflection of residents correctly entering 1 primary Current Procedural Terminology code for each surgical case. Programs should be aware of a general increase in case number since 2014 and acknowledge the fact that some procedure types may be given priority from a logging standpoint when multiple Current Procedural Terminology codes apply.
Effects of Marijuana Use in Patients with Orthopaedic Trauma
Authors: Sheppard Sean G. , Wall Pelle V. , Wheatley Benjamin , Kent William
Published: February 2022

➢ The use of cannabis and cannabis-related products has increased dramatically in the last 2 decades. As states continue to legalize cannabis products, it is important for surgeons to understand the effects they may have on patients who have sustained orthopaedic trauma.

➢ Cannabinoids have been shown to decrease the severity of certain symptoms related to traumatic brain injury as well as posttraumatic stress disorder.

➢ Cannabinoids can modulate the body’s endocannabinoid system, which can play an important role in bone homeostasis. Activation of cannabinoid receptors has been shown to be bone-protective in adults.

➢ Venous thromboembolism is a major concern for trauma patients. Cannabis use has been linked to overall increased rates of venous thromboembolism events.

➢ Literature regarding human-based cannabis studies is sparse; however, the growing field is opening new opportunities for research of this topic.
Geochemistry and Provenances of the Paleoproterozoic Terrigenous Rocks of the Urik–Iya Graben (Southern Siberian Craton)
Authors: Motova Z.L. , Donskaya T.V. , Gladkochub D.P. , Mazukabzov A.M. , Demonterova E.I.
Published: February 2022

—We present results of petrographic, geochemical, and isotope-geochemical (Sm–Nd) studies of the Paleoproterozoic terrigenous rocks of the Urik–Iya graben, which formed during three successive stages of extension. We have established that these rocks are both petrogenic (Ingashi and Daldarma formations) and lithogenic (Ermosokha Formation) sediments. It is concluded that the rocks in the lower and, partly, middle parts of the Urik–Iya graben section (Ingashi Formation and Lower Daldarma Subformation) resulted mostly from the disintegration of felsic igneous rocks. The terrigenous rocks in the middle part of the section (Upper Daldarma Subformation) might have formed through the disintegration of both felsic and mafic igneous rocks. The rocks in the upper part of the section (Ermosokha Formation) probably formed from the underlying terrigenous rocks of the Ingashi and Daldarma formations. The Nd model age (2.3–2.5 Ga) estimated for the rocks of the three studied sections points to a predominance of rocks of the Neoarchean and Paleoproterozoic upper continental crust in the provenance.
Sierra Nevada Willow Flycatcher Decline Continues but Losses Abate at Two Restored Meadows
Authors: Loffland Helen L. , Schofield Lynn N. , Siegel Rodney B. , Christman Beth
Published: February 2022

Willow Flycatcher (Empidonax traillii) populations have been declining across the western United States for decades. The Sierra Nevada–southern Cascades population in California is especially vulnerable, with fewer than 200 pairs remaining. Hydrologic restoration has been recommended for conserving this population. Other riparian songbirds have increased in response to restoration, but little is known about how restoration has affected the Willow Flycatcher. The Little Truckee River has long been a stronghold for the Willow Flycatcher, and the demography of the population there was studied intensively from the late 1990s through 2010. Baseline data from that study provided an opportunity to gauge the species’ response to pond-and-plug restoration projects completed at two meadows within the study area in 2009 and 2010. We aggregated and analyzed data from Willow Flycatcher surveys from 1997 through 2019 at the two restored meadows as well as nine nearby unrestored meadows with at least two Willow Flycatcher territories at some time during the demographic study. At most meadows, the number and density of Willow Flycatcher territories declined over the two-decade study period. However, losses at the unrestored meadows were significantly greater than at the restored meadows, where territory density clearly did not collapse following the disturbance caused by restoration and then remained largely stable thereafter. Within large meadows already occupied by Willow Flycatchers, meadow restoration that restores hydrologic function and increases flooding over creekbanks may be an effective strategy for stabilizing declining Willow Flycatcher populations in the Sierra Nevada.
Observation of unconventional many-body scarring in a quantum simulator
Authors: Su Guo-Xian , Sun Hui , Hudomal Ana , Desaules Jean-Yves , Zhou Zhaoyu , Yang Bing , Halimeh Jad , Yuan Zhen-Sheng , Papic Zlatko , Pan Jian-Wei
Published: February 2022

The ongoing quest for understanding nonequilibrium dynamics of complex quantum systems underpins the foundation of statistical physics as well as the development of quantum technology. Quantum many-body scarring has recently opened a window into novel mechanisms for delaying the onset of thermalization, however its experimental realization remains limited to the $\mathbb{Z}_2$ state in a Rydberg atom system. Here we realize unconventional many-body scarring in a Bose--Hubbard quantum simulator with a previously unknown initial condition -- the unit-filling state. Our measurements of entanglement entropy illustrate that scarring traps the many-body system in a low-entropy subspace. Further, we develop a quantum interference protocol to probe out-of-time correlations, and demonstrate the system's return to the vicinity of the initial state by measuring single-site fidelity. Our work makes the resource of scarring accessible to a broad class of ultracold-atom experiments, and it allows to explore its relation to constrained dynamics in lattice gauge theories, Hilbert space fragmentation, and disorder-free localization.
Immune Checkpoint Inhibitor Induced Vitiligo in Non-Melanoma Patients: Characterization and Management
Authors: Lo Jonathan , Hanania Hannah , Keiser Monika , Patel Anisha B
Published: February 2022

Purpose: This study highlights the range of non-melanoma cancers where ICI-induced vitiligo can be present and challenges the exclusivity of this phenomenon to melanoma. We believe our manuscript will encourage awareness in our colleagues and stimulate interest in further studies to elucidate the mechanisms of ICI-induced vitiligo in both melanoma and non-melanoma cancers, and to understand whether this phenomenon holds the same positive prognostic value in both cancer groups.Methods: This is a retrospective cohort study from a single-institution’s electronic medical record for cancer patients treated with ICIs who subsequently developed vitiligo. Results: We identified 151 patients with ICI-induced vitiligo, 19 (12.6%) non-melanoma and 132 (77.4%) melanoma patients. Time to onset of vitiligo was nearly doubled in the non-melanoma cohort, however, this is confounded by possible delayed diagnosis or under reporting of this asymptomatic condition in patients who do not regularly receive skin exams. The majority of patients had a stable course of vitiligo with 91.4% receiving no treatment in this largely Caucasian cohort. Two patients with non-melanoma cancers and Fitzpatrick type IV or above skin received treatment with narrowband ultraviolet B light therapy and topical steroids with near-complete response. Conclusions: This study highlights the occurrence of ICI-induced vitiligo in a variety of non-melanoma cancers, where skin of color patients will be more prevalent and the need for treatment will potentially be more urgent. Further study is needed to elucidate the mechanism of ICI-induced vitiligo and determine if non-melanoma cancers have the same association between vitiligo and increased tumor response.
Efficacy and Safety of Verapamil Through Indwelling Pleural Catheters in the Treatment of Malignant Pleural Effusion.
Authors: Zhang Yu , Wei Feifei , Zhu Yingwei , Liang Yajing , Xu Zihui , Cheng Tao , Xu Kequn
Published: February 2022

Objective: The clinical efficacy and safety of verapamil combined with anti-tumor drugs through pleural perfusion in the malignant pleural effusion(MPE) were observed. Methods: From January 2013 to June 2019, 79 patients with MPE were randomized. There were 37 cases in control group and 42 cases in the treatment group. After MPE were completely drained, anti-tumor drugs or verapamil combined with anti-tumor drugs were perfused through indwelling pleural catheters(IPCs). In the control group: interleukin-2(IL-2) 3M units and cisplatin; In the treatment group: IL-2 3M units, cisplatin and verapamil. After 1 cycle of treatment, the clinical efficacy and toxic side response were evaluated as well as median survival and overall survival. Results: After treatment, 2 cases acquired complete remission (CR) and 17 cases acquired partial remission (PR). The efficacy (CR add PR) was 51.35% in the control group; 6 cases acquired CR and 28 cases acquired PR. The efficacy (CR add PR) was 80.95% in the treatment group; The efficacy was significantly different in the two group (p<0.05). Median survival was 4 months in the control group and 13 months in treatment group. The over survival(OS) was significantly different in the two group (p<0.05). After verapamib combined with chemotherapy were perfused, the patient had appeared Ⅰ~Ⅱ degree reaction and all were relieved in a short period of time. Among them, 17 cases appeared leukopenia (40.47%), 23 cases had nausea and vomiting (54.76%), 10 cases appeared diarrhea (23.80%), 6 cases appeared had hair loss (14.28%), 19 cases appeared fever (45.23%), 9 cases appeared liver impairment (21.42%). The toxic side reactions and adverse cardiovascular effects in treatment group was no significant different from them of in the control group. Conclusion: The therapy of verapamil combined with anti-tumor drugs through IPC is effective and safe in the MEP.
Helicobacter pylori eradication failure in patients don't receive antibiotics with high resistance and have good compliance: a retrospective study
Authors: Xu Canxia , Luo Ju , Zhao Wenfang , Chi Jingshu , Liu Peng , Xie Xiaoran
Published: February 2022

Background: The eradication rate of the standard bismuth-containing quadruple therapy for Helicobacter pylori infection has gradually decreased in China, even patients don't receive antibiotics with high resistance and have good compliance.Objective: To investigate why patients experienced standard bismuth-containing quadruple therapy (not include clarithromycin, metronidazole and levofloxacin) with good compliance still eradication failure, we performed a retrospective, single center study to identify causes of treatment failure.Methods: Patients with H.pylori infection who were treated with standard bismuth-containing quadruple therapy (not include clarithromycin, metronidazole and levofloxacin) and received a test of cure at The third xiangya hospital between Oct. 2017 and May. 2021 were enrolled. Demographic and clinical data were recorded. Eradication rates were calculated and compared between regimens and subgroups. Logistic regression analysis was performed to identify risk factors of eradication failure. Results: nine hundred and seventy five patients were included in the final analysis, 891 patients were successful eradicated, the total successful eradication rate was 91.4%. The quadruple therapy containing amoxicillin plus doxycycline achieved the highest eradication rate (93.0%), followed by therapy that consisted of amoxicillin plus furazolidone (92.1%) and doxycycline plus furazolidone (90.8%). There was no significant difference in the eradication rate between these groups. Logistic regression analysis found that male (OR：1.984；95%CI：1.176-3.345), 45-years old and above (OR：2.902；95%CI：1.628-5.171) were associated with an increased risk of eradication failure. In primary therapy, Male (OR：2.085；95%CI：1.188-3.658), 45-years old and above (OR：3.072；95%CI：1.659-5.688), the history of antibiotic abuse (OR：2.624；95%CI：1.267-5.436) and eating out (OR：1.923；95%CI：1.034-3.577) were associated with an increased risk of eradication failure.Conclusions: Male, aged (≥45years old) are factors affecting H.pylori eradication failure in patients don't receive antibiotics with high resistance and have good compliance. Male, aged (≥45years old), the history of antibiotic abuse and eating out are factors affecting H.pylori primary eradication failure in patients don't receive antibiotics with high resistance and have good compliance.
Effect of CPB Glucose Levels on Inflammatory Response After Pediatric Cardiac Surgery
Authors: Zeng Zhi-Hua , Yu Xin-Yi , Liu Xiao-cheng , Liu Zhi-Gang
Published: February 2022

Background: Systemic inflammatory response syndrome (SIRS) is a common complication after cardiac surgery. There are no definite optimal glycemic threshold for pediatric patients receiving open-heart surgery with CPB. The study aimed to investigate the optimal cardiopulmonary bypass (CPB) glucose in patients undergoing cardiac surgery.Methods: We enrolled children with congenital heart disease who underwent surgical repair between June 2012 and December 2020. We included only patients who underwent cardiac surgery with CPB. The primary outcome was severe SIRS. A two-piece-wise regression model was applied to examine threshold effect of CPB glucose on severe SIRS.Results: A total of 7350 patients were enrolled in the present study, of whom 3895 (52.99%) are female. After potential confounders were adjusted, non-linear relationship was detected between CPB glucose and severe SIRS, whose turning point was 8.1. By gender, the J-shaped risk curve for female patients is not significantly different from the risk curve for male patients. With CPB glucose < 8.1mmol/L, the estimated dose-response curve was consistent with a horizontal line. However, the prevalence of severe SIRS increased with increasing glucose up to the turning point (Glucose > 8.1mmol/L); the odds ratio (OR) of the Glucose was 2.13 (95% CI: 1.99-2.28). Conclusions: The present study indicates the association of CPB glucose with inflammatory response after pediatric cardiac surgery. The patients might have the best outcomes with the optimal CPB glucose no more than 8.1mmol/L.
Entanglement Between Nanoelectromechanical Systems Mediated by a Transmission Line Resonator
Authors: Neto Olimpio Pereira de Sa
Published: February 2022

In this letters, is considered a simple chip composed of three devices, where we have two nanoelectromechanical systems capacitive coupling with a transmission line resonator, in which this interaction is approximated to two nondegenerate parametric oscilator interaction. For Entanglement analysis, we take two identical nanoelectromechanical systems with a thermal initial state.
Development of a Multiplex RT- PCR Assay for Simultaneous Detection of Four Potential Zoonotic Swine Enteric RNA Viruses
Authors: Wang Yue , Werid Gebremeskel Mamu , Ibrahim Yassein M. , Zhang He , Pan Yu , Zhang Lin , Xu Yunfei , Zhang Wenli , Wang Wei , Chen Hongyan
Published: February 2022

Swine enteric viruses like porcine Sapovirus (SaV), porcine encephalomyocarditis virus (EMCV), porcine rotavirus A (RVA) and porcine astroviruses (AstV) are potentially zoonotic viruses or suspected of potential zoonosis. These viruses have been detected in pigs with or without clinical signs and often occur as coinfections. Despite the potential public health risks, no assay for detecting them all at once has been developed. Hence, in this study, a multiplex RT-PCR (mRT-PCR) assay was developed for the simultaneous detection of SaV, EMCV, RVA and AstV from swine fecal samples. The PCR parameters were optimized using specific primers for each target virus. The assay's sensitivity, specificity, reproducibility, and application to field samples have been evaluated. Using a pool of plasmids containing the respective viral target fragments as a template, the developed mRT-PCR successfully detected 2.5 × 103 copies of each target virus. The assay's specificity was tested using six other enteric viruses as a template and did not show any cross-reactivity. A total of 280 field samples were tested with the mRT-PCR assay. Positive rates for SaV, EMCV, RVA, and AstV were found to be 24.6% (69/280), 5% (14/280), 4.3% (12/280), and 17.5% (49/280), respectively. Compared to performing separate assays for each virus, this mRT-PCR assay is a simple, rapid, and cost-effective method for detecting mixed or single infections of SaV, EMCV, RVA, and AstV.