bluuebunny/crossref_metadata_2025 huggingface dataset:
The Influence of Conservative Tillage Systems on Physico-Chemical Properties and Yield under a Cambic Chernozem from Northeastern Part of Romania
Authors: Burtan Lavinia , Țopa Denis , Jităreanu Gerard , Calistru Anca Elena , Răus Lucian , Cara Irina Gabriela , Sîrbu Carmen , Cioroianu Traian
Published: June 2023

The long-term experiment was carried out during 2005-2018, with samples collected on the experimental farm of the University of Agricultural Sciences and Veterinary Medicine in the city of Iasi (47º07` N latitude, 27º30` E longitude). The soil under investigation is classified as Cambic Chernozem (WRB) with a clay-loamy texture. Initial physical characteristics of the soil on 0-20 cm depth were: bulk density 1.33 g.cm-3 , pH (1:2.5) 6.23, clay 364.2 g.kg-1 , silt 263.2 g.kg-1 , loam 372.6 g.kg-1 , humus 2.95%. In the last 5 years a continuous maize cropping system was used. The tillage treatments included: (1) No-till: direct drilling in untilled soil with a disc drill without previous removal of residues, using a FABIMAG FG01 seeder (NT); (2) a reduced system using a chisel at 22-25 cm depth, after harvest without overturning the furrow (RT); (3) moldboard ploughing after harvest to a soil depth of 28-30 cm (CT). The crumbled and loosened soil was turned over and thereby residues were fully incorporated into the soil. After the harvest of pre-crop, stubble breaking (disking to the depth 10 cm) was used. Seedbed preparation was applied using a compactor after chisel and conventional tillage. In spring the weeds were suppressed by total herbicides before seeding. Crop-specific fertilization was performed according to good agricultural practice. Combine harvest was performed in October (between 5th and 28th) using a Wintersteiger Delta Plot Combine. Tillage systems affected soil penetration resistance (PR) under maize crop only for certain soil depths. At 0-5 cm depth, the highest value (0.78 MPa) was recorded on no-till system, whilst in the case of the other two variants the values ranged from 0.56 to 0.61 MPa. In CT variant at 30-40 cm, we noticed a compacted layer (2.54 MPa) indicating the existence of hardpan.
Effects of Fungicides, Row Spacing and Cultivar on Potato Biomass and Yield
Authors: Hermeziu Manuela , Morar Gavrilă , Ştefan Floriana Maria , Hermeziu Radu
Published: June 2023

Trials were performed to the National Institute of Research and Development for Potato and Sugar Beet between 2014-2016. Experimental design was completely randomized with four replicates, two planting densities (53,300 plants/ha, respectively 44,400 plants/ha) and two programs of fungicides application (only contact products - TECH 1; contact, translaminar and systemic product - TECH 2). Analysed varieties were Riviera (very early and very sensitive to late blight variety), Christian and Roclas (medium early and moderately susceptible to late blight varieties). The highest yields were obtained in variety Roclas (between 877 and 1048 g/plant), compared with yields that were recorded in late July in Riviera (between 698 and 732 g/plant) and Christian (between 668 and 820 g/plant) varieties.
The Characteristics of Poral Space as Habitat of Soybean Roots and Rhizobium Nodules
Authors: Eftene Alina , Mușat Iulian Bogdan , Mușat Marian , Manea Alexandrina , Răducu Daniela
Published: June 2023

The objective of the paper was to emphasize the characteristics of the poral space (quantified according to their size and shape) of an intensely irrigated soil, representing the habitat for soybean roots and Rhizobium bacteria nodulation. The studied site is located in Southern Bărăgan Plain, Perișoru region. The soil is Vermic Chernozem (according to SRTS-2012) formed in carbonate loess like deposits. The climate is temperate continental with an average annual temperature of 10.8°C, and an average annual precipitation of 480 mm. The poral space was quantitatively evaluated at microscopic scale, using image analysis on oriented soil thin sections with the help of an image-analyzer computer. The image analysis allowed the quantitative evaluation at microscopic scale of the undisturbed structure and the adjacent porosity, in 2-D dimension (in thin sections). The pores were divided according to their shape in three classes (regular, irregular and elongated pores), and further each shape class was divided into seven size classes according to the equivalent pore diameter (ranging between 100 and >1000 µm). The result showed, unspecific conditions in the studied Chernozem, thus: Ap horizon was more compacted than the underlined Apt, consequently the total porosity was lower (0.21 m2 m-2 ) into the top Ap horizon, comparing to the underlined Apt (0.33 m2 m-2 ). In agreement with the data obtained by means of image analysis (pores quantified according to their size and shape), the oriented thin sections gave a clear representation of the genesis, location and the characteristics of the poral space. The soybeans roots developed mainly into the areas with intense biological activity. The soil macro- and mesofauna proved to be good habitat builders for soybean roots and the Rhizobium nodules, even in the conditions of a droughty period with the irrigation application delay.
The Public Goods and the Multi-Annual Variation of Biodiversity Associated to Soybean Crop
Authors: Manea Alexandrina , Mușat Iulian Bogdan , Eftene Alina , Mușat Marian , Răducu Daniela
Published: June 2023

The objectives of the study were: to emphasize the public goods associated to soybean crop; and to qualitatively appreciate the multi-annual variation of soil biodiversity cohabitating with the soybean roots and the Rhizobium bacteria. The researchers were performed in the Eastern part of the Romanian Plain, in Southern Bărăgan Plain, Perișoru region. The soil is Vermic Chernozem (according to SRTS-2012 and WRB-SR-2014) formed in carbonate loess like deposits. The climate is temperate continental with the average annual temperature of 10.8°C, and the average annual precipitation of 480 mm. The main environmental public goods associated with the soybean crop and analyzed in this paper were: 1) soil quality and land capability; 2) water quality and availability; 3) biodiversity of agricultural land. Soil quality was analyzed based on the analytical data of physical, hydro-physical and chemical parameters of the soil. The land capability was quantified based on the values of the ecopedological indicators used for the land evaluation, both for land favourability and land quality. In this respect, for soybean, 72 points were obtained, which included the land from the studied site in the third class of favourability. The quality and the availability of water resources are also public goods associated with soybean crop, thus the water from the wells (located in the studied plot) was analyzed, the data showing normal limits for all analyzed water parameters. Regarding the multi-annual variation of the biodiversity, under intensive/irrigated soybean crop, the soil biodiversity did not change, while the upper-ground biodiversity was closely related to the plant changes into the crop rotation and consequently, many species being specialized accompany each crop within the crop rotation.
IDENTIFIKASI KARAKTRERISTIK SENI LUKIS TEBESAYA
Authors: Haryanta I Putu Fendy Puja , Sujana I Made , Pendit I Komang Dewanta , Adiputra Agus Mediana
Published: June 2023

Seni lukis tradisional merupakan karya seni lukis yang dibuat melalui pakem-pakem atau aturan yang sudah ada yang di lakukan secara turun-temurun khususnya seni lukis daerah Tebesaya. adapun teknik seni lukis Tebesaya yaitu sketsa, nyawi, ngabur, nyelah, ngeskes, nguap, mupur nyenter, memasangkan warna ke objek, ngeskeske dua, nyelah ke dua, dan ngelem. Dalam hal penelitian ini dilakukan di Tebesaya. adapun tema-tema yang diangkat yaitu tarian Bali seperti tari barong, tari baris, tari jauk manis, dan tari Bali lainnya. Adapun tujuan penelitian yang di lakukan adalah untuk mengetahui identifikasi karakteristik seni lukis Tebesaya penelitian ini di lakukan di daerah Tebesaya. metode yang di gunakan untuk penelitian yaitu metode pengumpulan data seperti (1)observasi (2)wawancara (3)dokumentasi selanjutnya anlisis dilanjutkan dengan teknik deskriptif dan  kualitatif.Hasil dari penelitian bahwa identifikasi karakteristik seni lukis Tebesaya yaitu lebih mengarah ke warna yellow ochre atau lebih ke coklat mebih mengarah ke gelap bisa di katakan warna shoft, dengan proposi anatomi yang memanjang hampir menyerupai ke bentuk pewayangan serta hampir semua objek yang di lukiskan dalam media kanvas sua tampak detail
THE EFFECT OF JOB DESCRIPTION ON EMPLOYEE PERFORMANCE WITH COMPENSATION AS AN INTERVENING VARIABLE (Case Study on Nurse and Medical Doctor of Chicago District)
Authors: Jonathan Dingel  , Mark G Maffet
Published: June 2023

This study aims to determine how the influence of job descriptions on employee performance with compensation as an intervening variable for Nurse and Medical Doctor of Chicago District. The research method used is the method of qualitative data and quantitative data. While the data used is primary data. The method of data analysis in this study uses simple linear regression analysis to obtain a comprehensive picture of the effect of job description variables on employee performance with compensation as an intervening variable for Nurse and Medical Doctor of Chicago District using the SPSS 25 for Windows program. To find out whether there is a significant effect of the independent variable on the dependent variable, a simple linear regression model is used. The results of testing the hypothesis using simple regression analysis and t test show that: that the t-table value of the job description variable is 4.181 > the t-table value (df: 38, α: 5%) is 1.685 so it can be concluded that the job description has a positive effect and significant to employee performance. Furthermore, from table 4.17 it can also be seen that the t-table value of the compensation variable is 1.186 < the t-table value (df: 38, α : 5%) is 2.024 so it can be concluded that compensation has no significant effect on employee performance.
THE INFLUENCE OF ORGANIZATIONAL CULTURE ON EMPLOYEE PERFORMANCE WITH COMPENSATION AS AN INTERVENING VARIABLE (Case Study on Employees of the Residential Area Housing Office And Cleanliness of the City of Wisconsin-milwaukee)
Authors: Mohsen Bahmani Oskooee  , Ian Wooton
Published: June 2023

In this study the population is . 30 employees of the Housing and Settlement Area Office of the City of Wisconsin-milwaukee. Because the target population is less than 100, the sampling technique used is the census method, in which the entire population, totaling 30 employees of the Residential and Cleanliness Office of the City of Wisconsin-milwaukee, will be used as the research sample. In other words, data analysis activities are raw data that has been collected needs to be categorized or divided into several categories or groups, shortened in such a way that the data can answer problems according to research objectives and can test hypotheses. With the results of the first hypothesis being accepted, it means that Organizational Culture (X) has a positive and significant effect on compensation (Y1). the second hypothesis is accepted, meaning that Organizational Culture (X) has a significant effect on Employee Performance (Y2). the third hypothesis is rejected, meaning that compensation (Y1) has no positive and significant effect on employee performance (Y2). The calculation results obtained show that the indirect effect through the Y1 variable is smaller than the direct effect on the Y2 variable.
RELATIONSHIP BETWEEN MOTHER'S KNOWLEDGE ABOUT CLEAN AND HEALTHY BEHAVIOR (PHBS) AND DIARRHEA IN CHILDREN AGED 0-3 YEARS AT THE AEK NAULI HEALTH CENTER IN PEMATANGSIANTAR
Authors: Doortua  , Jeni Raulina Br Siregar  , Minda Rahel Simatupang
Published: June 2023

The incidence of diarrhea is the inadequate provision of clean water, water contaminated with feces, lack of sanitation facilities, unhygienic disposal of feces, dirty personal and environmental hygiene, and inappropriate food preparation and storage. Many factors directly or indirectly become factors driving the occurrence of diarrhea, consisting of agent, host, environment and mother's lack of knowledge about clean and healthy living behavior. The purpose of this research is aHaUh to find out the relationship between mother's knowledge about clean and healthy living behavior (PHBS) and the incidence of diarrhea in children aged 0-3 at the Aek Nauli Health Center in 2017. This type of research is descriptive quantitative with a cross-sectional research design. The population in this study were all mothers who had children aged 0-3 years who came to visit the Aek Nauli Health Center in 2017 with an average monthly visit of 30 people. Sampling using a total sampling technique of 30 people. Based on the results of the study, the majority of mothers' knowledge about PHBS at the Aek Nauli Health Center had less knowledge, as many as 22 people (73,300). The majority of respondents reported that the incidence of diarrhea at the Aek Nauli Health Center was 25 people (83 30). For this reason, it is hoped that mothers will increase their knowledge about PHBb by seeking more information, especially from health workers so that the incidence of diarrhea in children is reduced.
THE RELATIONSHIP KNOWLEDGE AND ATTITUDE OF PREGNANT WOMEN IN FULFILLING NUTRITION NEEDS WITH NUTRITIONAL STATUS IN RAYA PUSKESMAS, RAYA DISTRICT
Authors: Yunardi
Published: June 2023

Nutritional status is a measure of success in fulfilling nutrition for pregnant women. Nutrition for pregnant women is the nutrition needed in large quantities to fulfill the nutrition of the mother herself and the development of the fetus she contains. Fulfilling the nutritional needs of pregnant women is closely related to the level of maternal knowledge about nutrition during pregnancy. Meanwhile, the attitude of the mother in fulfilling the needs is what is seen and known by the mother in fulfilling nutritional needs through information. Correlation descriptive research method using primary data through a questionnaire based on the knowledge and attitudes of pregnant women. The sampling technique in this study was purvosive sampling, that is, the researcher determined the sample taken because of certain considerations. From the results of this study it was concluded that there was no relationship between knowledge of pregnant women in fulfilling nutritional needs with nutritional status at the Raya Public Health Center, Raya District, Simalungun Regency, this was evidenced by the results of the chi-square test with a p-value = 0.163 and there was a relationship between attitudes of pregnant women in meet nutritional needs with nutritional status at the Panombeian Panei Health Center, Panombeian Panei District, Simalungun Regency in 2016, this is evidenced by the results of the chi-square test with a p-value = 0.004. Pregnant women are expected to have more regular check-ups for their pregnancies with health workers and actively participate in counseling conducted by health workers to obtain information related to nutrition during pregnancy.
THE EFFECT OF COMPENSATION ON MEDICAL DOCTOR AND NURSE WITH WORK DISCIPLINE AS AN INTERVENING VARIABLE (CASE STUDY OF MEDICAL DOCTOR AND NURSE IN UNITED STATES PUBLIC HEALTH SERVICE)
Authors: Zhenyu Cui  , John Zysman
Published: June 2023

The sampling technique used was the census method, where the entire population of 40 Medical Doctor and Nurses at Medical Doctor And Nurse In United States Public Health Service, was sampled in this study. Data collection techniques by conducting a review study of books, literature, records, and reports that have something to do with the problem being solved. The results of this study are stated that: From the table above, a tcount value of 5.399 is obtained with α = 5%, ttable (5%; nk = 38) obtained a ttable value of 1.685. From this description it can be seen that tcount (5.399) > ttable (1.685) , likewise with a significance value of 0.00 <0.05, it can be concluded that the first hypothesis is accepted, meaning that the compensation variable (X) has a positive and significant effect on work discipline (Y1). tcount value of 2.939 With α = 5%, ttable (5%; nk = 38) obtained ttable value of 1.685 From this description it can be seen that tcount (2.939) > ttable (1.685), and its significance value is 0.00 <0, 05 it can be concluded that the second hypothesis is accepted, meaning that compensation (X) has a significant effect on Medical Doctor and Nurse performance (Y2). tcount value of 3.294 With α = 5%, ttable (5%; nk = 38) obtained ttable value of 1.685 From this description it can be seen that tcount (3.294) > ttable (1.685), and its significance value is 0.00 <0, 05, it can be concluded that the third hypothesis is accepted, meaning that work discipline (Y1) has a positive and significant effect on Medical Doctor and Nurse performance (Y2). In the picture above the path analysis shows the direct effect of variable X on variable Y2 of 0.403.
PATTERN OF ANTIHYPERTENSION DRUG ADMINISTRATION IN HYPERTENSION PATIENTS IN OUTPATIENT TUAN RONDA HOSPITAL PEMATANG RAYA, SIMALUNGUN DISTRICT
Authors: Nurmala
Published: June 2023

Until now, hypertension is still a big challenge in Indonesia. In accordance with the 2013 Riskesdas data, the prevalence of hypertension is quite high, namely 25,896. This study aims to determine the pattern of administration of antihypertensive drugs to hypertensive patients at Tuan Rondahaim Hospital, Pematang Raya, Simalungun Regency. This research was conducted using a descriptive research design and data collected retrospectively. The material used is data from hypertension patient prescriptions at Tuan Rondahaim Hospital, Pematang Raya, Simalungun Regency. The number of samples used was obtained as many as 231 patients. The results obtained were that hypertension patients based on sex characteristics were mostly women 54.1196, the most age was 61 — 80 years 65.806. On the profile of antihypertensive drug use by patients, There are 5 classes of antihypertensives used. The most widely used anti-pertensive class Blocker (CCB) was the Calcium Channel amlodipine group of 61.03%, which was used by 141 patients, then the diuretic class of furosemide type was 41.9% used by 97 patients.
THE EFFECT OF WORK DISCIPLINE ON EMPLOYEE JOB SATISFACTION WITH INCENTIVES AS AN INTERVENING VARIABLE (Case Study on Medical doctor and Nurses in Wisconsin City Area)
Authors: Mohsen Bahmani-OSKooee  , Bob Feinberg
Published: June 2023

In this study, the population was employees of Medical doctor and Nurses in Wisconsin City Area, namely 31 people. Because the target population is less than 100, the sampling technique used is the census method, where the entire population is 31 employees of Medical doctor and Nurses in Wisconsin City Area. it can be concluded that the first hypothesis is accepted, meaning that work discipline (X) has a significant effect on job satisfaction (Y). the second hypothesis is accepted, meaning that incentives (Z) have a significant effect on job satisfaction (Y). the third hypothesis is rejected, meaning that incentives (Z) are not an intervening variable that mediates the effect of work discipline (X) on job satisfaction (Y).
Approximation and accumulation results of holomorphic mappings with dense image
Authors: Di Salvo Giovanni D.
Published: June 2023

We present four approximation theorems for manifold–valued mappings. The first one approximates holomorphic embeddings on pseudoconvex domains in $\mathbb{C}^n$ with holomorphic embeddings with dense images. The second theorem approximates holomorphic mappings on complex manifolds with bounded images with holomorphic mappings with dense images. The last two theorems work the other way around, constructing (in different settings) sequences of holomorphic mappings (embeddings in the first one) converging to a mapping with dense image defined on a given compact minus certain points (thus in general not holomorphic).
Constructing stable vector bundles from curves with torsion normal bundle
Authors: Licanic Sergio
Published: June 2023

Given a smooth irreducible curve $S$ with torsion normal bundle on a projective surface $X$, we provide a criterion for the non-emptiness of the moduli of slope stable vector bundles with prescribed Chern classes. The criterion is given in terms of the topology of the pair $(X,S)$.
Vanishing Morrey integrability for Riesz potentials in Morrey-Orlicz spaces
Authors: Mizuta Yoshihiro , Shimomura Tetsu
Published: June 2023

Our aim in this paper is to establish vanishing Morrey integrability for Riesz potentials of functions in Morrey-Orlicz spaces. We discuss the size of the exceptional sets by using a capacity and Hausdorff measure. We also give Trudinger-type exponential Morrey integrability for Riesz potentials of functions in Morrey-Orlicz spaces.
Linear resolutions and quasi-linearity of monomial ideals
Authors: Lu Dancheng
Published: June 2023

We introduce the notion of quasi-linearity and prove it is necessary for a monomial ideal to have a linear resolution and clarify all the quasi-linear monomial ideals generated in degree $2$. We also introduce the notion of a strongly linear monomial over a monomial ideal and prove that if $\mathbf {u}$ is a monomial strongly linear over $I$ then $I$ has a linear resolution (respectively is quasi-linear) if and only if $I+\mathbf {u}\mathfrak {p}$ has a linear resolution (respectively is quasi-linear). Here $\mathfrak {p}$ is any monomial prime ideal.
Capacities from moduli in metric measure spaces
Authors: Martio Olli
Published: June 2023

The concept of capacity is an indispensable tool for analysis and path families and their moduli play a fundamental role in a metric space $X$. It is shown that the $AM_p(\Gamma )$- and $M_p(\Gamma )$-modulus create the capacities, $\mathrm {Cap}_p^{AM}(E,G)$ and $\mathrm {Cap}_p^{M}(E,G)$, respectively, where Γ is the path family connecting an arbitrary set $E \subset G$ to the complement of a bounded open set $G$. The capacities use Lipschitz functions and their upper gradients. For $p > 1$ the capacities coincide but differ for $p=1$. For $p \geq 1$ it is shown that the $\mathrm {Cap}_p^{AM}(E,G)$-capacity equals to the classical variational Dirichlet capacity of the condenser $(E,G)$ and the $\mathrm {Cap}_p^{M}(E,G)$-capacity to the $M_p(\Gamma )$-modulus.
The AH conjecture for Cantor minimal dihedral systems
Authors: Scarparo Eduardo
Published: June 2023

The AH conjecture relates the low-dimensional homology groups of a groupoid with the abelianization of its topological full group. We show that transformation groupoids of minimal actions of the infinite dihedral group on the Cantor set satisfy this conjecture. The proof uses Kakutani–Rokhlin partitions adapted to such systems.
Profile of adverse drug reaction reports in South Africa: An analysis of VigiBase® for the year 2017
Authors: Steyn H
Published: June 2023

Background. The South African Health Products Regulatory Authority (SAHPRA) monitors the safety of health products by collecting and evaluating adverse drug reaction (ADR) reports submitted by healthcare professionals, patients and pharmaceutical companies. The reports are shared with the World Health Organization (WHO) Programme for International Drug Monitoring. A demographic and clinical profile of ADR reports will improve our understanding of ADR reporting in South Africa to enhance training of reporters at all levels.

Objectives. This study describes the demographic and clinical profile of spontaneous ADR reports received by the SAHPRA during the year 2017.

Methods. A retrospective, cross-sectional study was conducted to describe all ADR reports submitted by South Africa to VigiBase®, the WHO global database of Individual Case Safety Reports (ICSRs), during 2017. The demographic profile included patient characteristics (age and sex), type of reporter and the vigiGrade™ completeness score for each ICSR. The clinical profile included characteristics of the case, medicine(s) and reaction(s).

Results. A total of 8 438 reports with a mean completeness score of 0.456 (SD = 0.221) were assessed. Females and males represented 61.96% and 33.05% of cases, respectively (if sex was reported). All age groups were represented; however, 76.28% involved adults (aged 19-64 years). Physicians submitted the most reports (39.66%). Consumers were the reporters in 29.39% of cases. Pharmacists submitted only 4.45% of the reports. Anti-infective medicines were the most reported Anatomical Therapeutic Class (20.08%), while Human Immunodeficiency Virus was the top indication reported (10.27%). The highest number of MedDRA preferred terms used to describe reactions belonged to the System Organ Class, general disorder and administration site conditions. In 55.87% of the reports, the cases were reported as serious and 12.47% fatal. Death was the most reported MedDRA preferred term used to describe a reaction (5.17%).

Conclusions. This was the first study that described ADR reports received by SAHPRA and improves our understanding of reporting in the country. The core clinical elements that are important in signal detection were often not included in reports. The findings demonstrated that patients were more active contributors to the national pharmacovigilance database than pharmacists. Reporters should be trained in pharmacovigilance and ADR reporting processes to increase the quantity and completeness of reports.
Ivermectin drug induced liver injury
Authors: Sonderup Mark , Mudini Washington , Spearman Wendy
Published: June 2023

Ivermectin remains a popular, albeit unproven, therapy used in both the prevention and treatment of COVID-19. We discuss a patient who developed jaundice and a liver injury 3 weeks after initiating ivermectin for COVID prevention.  Liver histology demonstrated a pattern of injury that was both portal and lobular, with a bile ductulitis as well with marked cholesasis. She was managed with low dose corticosteroids, later tapered and withdrawn. She remains well a year after presenting.
Behavioural Medicine: Strengthening approaches to address co-morbid chronic physical and mental disorders
Authors: Stephan Rabie  , Joska John A.
Published: June 2023

South Africa is confronted with multi-morbid chronic physical and mental disorders. The relationships between these conditions are often multidirectional and result in a variety of adverse mental and physical health outcomes. The risk factors and perpetuating conditions in multi-morbidity are potentially modifiable through effective behaviour change. However, in South Africa, interventions and clinical care that address these co-occurring factors have traditionally functioned in a vacuum, created by a lack of formalised multidisciplinary collaboration. In high-income settings, the field of Behavioural Medicine was established in recognition of the importance of psychosocial factors in illness and assumes that the presence of physical concerns can be influenced by psychological and behavioural factors. The large body of evidence supporting Behavioural Medicine has afforded the field global recognition. Yet, it remains an emerging field in South Africa and on the African continent. The purpose of this paper is to contextualise the field of Behavioural Medicine in South Africa and present a way forward to establish the field in our context.
Ķermeņa sensoru tīkls tā virsmas formas rekonstrukcijai
Authors:   , Ancāns Armands
Published: June 2023

Promocijas darbs veltīts jaunu metožu izpētei ķermeņu formas rekonstrukcijai, izmantojot iegultus orientācijas sensorus. Pētījumā izstrādātas divas būtiskas inovācijas: 1) pieeja, kas, izmantojot orientācijas sensorus elastīgās struktūrās, ļauj rekonstruēt telpisku ķermeņu formu; 2) pieeja optimizētai datu ieguvei ķermeņa sensoru tīklos ar lielu skaitu sensoru mezgliem. Abas piedāvātās metodes validētas laboratorijas apstākļos, izmantojot eksperimentālo maketu ar 26 orientācijas sensoriem, kas iestrādāti zigzagveida struktūrās. Rezultāti salīdzināti ar esošajām tehnoloģijām. Ņemot vērā rezultātu analīzi, sniegtas rekomendācijas sistēmas dizaina izvēlēm.
Laser system of cold atom optical clock in China Space Station
Authors: Liu Yun , Wang Wen-Hai , He De-Jing , Zhou Yong-Zhuang , Shen Yong , Zou Hong-Xin ,   Institute for Quantum Science and Technology, College of Science, National University of Defense Technology, Changsha 410073, China,   Hunan Key Laboratory of Mechanism and Technology of Quantum Information, Changsha 410073, China
Published: June 2023

The world's first space optical clock (SOC) developed in China, which is composed of five subsystems, i.e. an optical unit, a physics unit, an electronic control unit, a space optical frequency comb, and an ultrastable laser, was successfully launched with the Mengtian space laboratory on October 31, 2022, and entered into the China Space Station (CSS). Compact and stable laser is a key element for the operation of the SOC. The optical unit consists of 5 lasers with wavelengths of 461, 679, 689, 707 and 813 nm, respectively. With a synchronous-tuning-like scheme, high-quality external cavity diode lasers (ECDLs) are developed as the seeds. The linewidths of the lasers are all reduced to approximately 100 kHz, and their tuning ranges, free from mode hopping, are capable of reaching 20 GHz, satisfying the requirements for the SOC. With careful mechanical and thermal design, the stability of the laser against vibration and temperature fluctuation is sufficiently promoted to confront the challenge of rocket launching. While the power from the ECDL is sufficient for 679-nm repump laser and 707-nm repump laser, additional injection lock is utilized for the 461-nm laser and 689-nm laser to amplify the power of the seeds to more than 600 mW, so that effective first and second stage Doppler cooling can be achieved. To generate an optical lattice with deep enough potential well, over 800-mW 813-nm lasers are required. Therefore, a semiconductor tapered amplifier is adopted to amplify the seed to more than 2 W, so as to cope with various losses of the coupling optics. The wavelengths and output power values of the 5 lasers are monitored and feedback is controlled by the electronic control unit. All the modules are designed and prepared as orbital replaceable units, which can be easily replaced by astronauts in case failure occurs. Now the lasers are all turned on and operate normally in CSS. More data of the SOC will be obtained in the near future. At present stage, according to our evaluation, the continuous operation time of the SOC is limited by the injection locked lasers, which are relatively vulnerable to mode hopping. Hopefully, this problem can be solved by improving the laser diode preparing technology, or developing fiber lasers with compact frequency conversion modules.
Influence of wind-dominated thermal blooming on orbital angular momentum and phase singularity of dual-mode vortex beams
Authors: Xu Meng-Min , Li Xiao-Qing , Tang Rong , Ji Xiao-Ling ,   College of Physics and Electronic Engineering, Sichuan Normal University, Chengdu 610068, China
Published: June 2023

The effects of thermal blooming on orbital angular momentum (OAM) and phase singularity of dual-mode vortex beams under different wind directions and wind speeds are studied in this paper. Owing to the different symmetries of dual-mode vortex beams superimposed by different modes, the effects of thermal blooming on them depend on not only wind speed, but also wind direction. Based on the scalar wave equation and the hydrodynamic equation, a four-dimensional (4D) computer code to simulate the time-dependent propagation of dual-mode vortex beams in the atmosphere is devised by using the multiphase screen method and finite difference method. It is found that for a certain wind direction, the value of OAM increases with the wind speed decreasing because the thermal blooming becomes more serious, i.e. the thermal blooming effect promotes the OAM of dual-mode vortex beam to grow. For example, when the angle between the wind direction and the beam is 0 < θ < 50°, the OAM of the dual-mode vortex beams with a topological charge difference of 2 increases with wind speed decreasing, and there is an optimal angle (\begin{document}$ \theta \approx {20^ \circ } $\end{document}) to maximize OAM. Therefore, for a certain wind direction and wind speed, the OAM of dual-mode vortex beam propagating in the atmosphere can be larger than that in free space, and can be larger than the OAM of single-mode vortex beam. The dual-mode vortex beam with higher modes requires smaller wind speed to make its OAM larger than the OAM in free space. In addition, the larger the difference in topological charge between the two element beams of a dual-mode vortex beam, the more stable the OAM of the dual-mode vortex beam is. On the other hand, the evolution of linear edge dislocation singularity under atmospheric thermal blooming is also investigated in this paper. When the wind direction is perpendicular to the dislocation line, the linear edge dislocation singularity disappears. If the wind direction is parallel to the dislocation line, the linear edge dislocation singularity always exists. At other angles, the linear edge dislocation singularity will evolve into optical vortex pairs. The results obtained in this paper have a certain reference value for the propagation of lasers in the atmosphere and optical communication.
Chromosomal instability can favor macrophage-mediated immune response and induce a broad, vaccination-like anti-tumor IgG response
Authors: Hayes Brandon H. , Wang Mai , Zhu Hui , Phan Steven H. , Andrechak Jason C. , Chang Alexander H. , Dooling Lawrence J. , Tobin Michael P. , Marchena Tristan , Discher Dennis E.
Published: June 2023

Chromosomal instability (CIN), a state in which cells undergo mitotic aberrations that generate chromosome copy number variations, generates aneuploidy and is thought to drive cancer evolution. Although associated with poor prognosis and reduced immune response, CIN generates aneuploidy-induced stresses that could be exploited for immunotherapies. Macrophages, particularly, have been understudied in the CIN context. Here, through MPS1 inhibition-induced CIN in poorly immunogenic B16F10 mouse melanoma, we find that CIN- afflicted cancer cells skew macrophages towards an anti-cancer phenotype while also pushing them away from a pro-cancer one. We confirm these findings via RNA-sequencing, protein expression, and short-term tumor studies. These results further translate to
in vivo
efficacy in suppressing tumor growth: Mice can survive challenges of CIN-afflicted tumors. Long-term survival, however, is dependent on CD47 expression and IgG opsonization. Mice bearing CIN- afflicted tumors with wild-type CD47 levels see prolonged survival compared to their chromosomally stable counterparts, but all succumb. Mice bearing CIN-afflicted CD47 knockout tumors, however, show 28% long-term survival. When CD47 knockout was further paired with IgG opsonization, survival rate increased to 97%. Successful rejection and clearance of CIN- afflicted tumors induced
de novo
anti-cancer IgG antibodies that were multi-epitope and functionally promoted macrophage-mediated phagocytosis. These
de novo
IgG antibodies could also suppress
in vitro
tumoroid and
in vivo
tumor growth in a CD47 knockout context. These results highlight an unexpected therapeutic benefit from CIN when paired with maximal macrophage anti-cancer activity: an anti-cancer vaccination-like antibody response that can lead to durable cures and further potentiate cell-mediated acquired immunity.
Fasudil may alleviate alcohol-induced astrocyte damage by modifying lipid metabolism, as determined by metabonomics analysis
Authors: Zhao Huiying , Li Xintong , Zheng Yongqi , Zhu Xiaofeng , Qi Xunzhong , Huang Xinyan , Bai Shunjie , Wu Chengji , Sun Guangtao
Published: June 2023

Alcohol dependence is a chronic, relapsing encephalopathy characterized by compulsive craving for alcohol, loss of control over alcohol use, and the presence of negative emotions and physical discomfort when alcohol is unavailable. Harmful use of alcohol is one of the greatest risk factors for death, illness, and disability. Rho kinase inhibitors have neuroprotective effects. This study used metabonomics analysis to assess untreated astrocytes, astrocytes exposed to 75 mmol/L of alcohol, and astrocytes exposed to 75 mmol/L of alcohol and treated with 15 µg/mL fasudil for 24 h. One of the clearest differences between the alcohol-exposed and fasudil-treated alcohol-exposed groups was the abundance of lipids and lipid-like molecules, although glycerophospholipid metabolism was comparable in both groups. Our findings show that fasudil may alleviate alcohol-induced astrocyte damage by modifying lipid metabolism, providing a new approach for preventing and treating alcohol dependence.
Alcances de la adopción homoparental a la luz del interés superior del niño
Authors: Basoalto Riveros Constanza Pamela
Published: June 2023

Si la adopción busca propiciar al adoptado el mejor entorno posible para su crianza, educación y cuidado, la real pregunta sobre la admisibilidad de la adopción homoparental es si esta perjudica o no el resguardo del interés superior del niño. Por ello, este trabajo brinda diversas razones jurídicas y no jurídicas para arribar a una conclusión, examinando algunos de los conceptos involucrados en la problematización, como también las inconsistencias de los argumentos que rechazan la procedencia de la misma. Se sostiene, por tanto, que tales razonamientos fracasan en formular objeciones persuasivas a la crianza homoparental
Extra Pulmonary Tuberculosis in Pregnancy: A Case Report
Authors: Priya Annareddy Lakshmi , Ravi Patil N
Published: June 2023

Tuberculosis (TB) in pregnancy is a major health problem which possess a sustainable risk of morbidity to mother and fetus if not diagnosed and treated at correct time. The diagnosis in pregnancy is challenging, especially in the absence of lung involvement. It usually mimics other diseases as most of the patients with extra pulmonary TB present usually with nonspecific symptoms which misleads the diagnosis. Hence, it is very important to address even nonspecific symptoms in pregnancy as a neglected diagnosis and delayed treatment may lead to severe perinatal morbidity and mortality like fetal distress, preterm delivery, fetal growth retardation, seizures due to intra cranial space occupying lesion, perforation of intestinal lesions, pneumoperitonitis, high chances of intensive care unit admission for mother and neonate. Hereby, authors report two cases, one about a 29-year-old primigravida with numbness and paresthesia of unilateral limbs. She was diagnosed of intracranial tuberculoma and treated with Antitubercular Drugs (ATT) for nine months. She underwent a cesarean section in view of an intracranial space-occupying lesion. Another patient was a prima gravida who presented with persistent gastroenteritis symptoms like vomiting and diarrhea. She was diagnosed to have ileocecal mass with suspicion of malignancy or infectious aetiology. In view of deteriorating maternal condition, emergency cesarean section was done along with resection of ileocecal mass. On histopathological examination it was found to be ileocecal TB and she was started on ATT.
Influence of Gender on Stress among School Children: A Cross-sectional Study
Authors: Mishra Dheerendra Kumar , Singh Umesh Pratap , Maravi Prashant , Varma Akshat
Published: June 2023

Introduction: The perception of stress by students affects their academic performance significantly. Continuous exposure to stress for a long time can cause both physical illnesses (including heart disease), and mental illnesses (e.g., anxiety disorders). Furthermore, stress increases the risk of suicide in students which is an important cause of adolescent mortality. Perception of stressors depends upon the biological, social, and psychological factors of students. Moreover, biological differences between male and female students attributed to the significant difference in experiencing stress among them. Aim: To study the gender difference and stress levels among adolescent school students. Materials and Methods: A cross-sectional study was conducted in Government boys higher secondary school and Government girls higher secondary school Mauganj, a town of Madhya Pradesh, India, between August 2016 to September 2016. The state board of examinations and the Hindi medium of instruction were followed in the school. Total 40 study subjects, 24 males and 16 females were recruited for study after obtaining written informed consent from participants by simple random sampling method. The self-administered student stress scale was used to measure participants’ levels of stress and socio-demographic information, including age, sex, education, was recorded in semistructured data entry proforma. The data were summarised using means with standard deviations and frequencies with percentages. Comparative analyses between the genders were conducted using the Student’s t-test (for continuous variables). The p-value ≤0.05 was considered level of significance. Results: Total of 40 study participants included, mean age 16.2±2.2 years. A total of 24 were male students and 16 were female students, amongst included subjects. Majority of student’s family practiced Hindu religion. Total stress score was 84.3±7.5 for male and 96.2±5.5 for female students (p=0.001). Conclusion: Significant amounts of stress were felt by students in high school. Male and female students perceived similar levels of stress in their academic and vocational domains, but female students felt significantly more stress in their financial, emotional, familial, and social domain. Student total stress levels were significantly higher for female students than male students.
Endoscopic and Intraoral Approach for Removal of an Ectopic Third Molar associated with a Dentigerous Cyst in the Maxillary Sinus: A Case Report
Authors: Bilginaylar Kani , Inancli Hasan Mete , Kneebone Meliz
Published: June 2023

Dental ectopia is the presence of deciduous, permanent, or supernumerary teeth in non dentate areas. It is very rare, especially in the maxillary sinus. Treatment is surgical removal because left untreated, there is a tendency to form a cyst, tumour, or lesion that can cause the perforation of the orbital floor and the obstruction of the nasal cavity. Although, panoramic radiography is the common form of radiological examination for this type of eruption, Cone Beam Computed Tomography (CBCT) is the gold standard for pinpointing the exact location of the ectopic tooth and evaluating the characteristics of any associated lesion prior to a surgical procedure. A 17-year-old woman was referred with swelling, asymmetry, and local pain in her right maxillary region. On radiological examination, an ectopic third molar surrounded by a dentigerous cyst obstructing both the right maxillary and ethmoid sinuses was observed. The tooth was attached to the zygomatic bone, right under the orbital floor. Ectopic maxillary third molars are extracted mainly by the Caldwell-Luc technique but also by nasal endoscopy. The treatment of this eruption and its management is heterogeneous and multidisciplinary. In the present case, under general anaesthesia, the ectopic tooth and all cystic tissue occupying the entire right maxillary and ethmoid sinuses were successfully enucleated with an intranasal endoscopic approach by an otolaryngologist and with lateral sinus antrostomy, utilising a standard Caldwell-Luc approach, by an oral and maxillofacial surgeon. After the 6th and 12th months, the patient had no signs of sinus infection and had an uneventful recovery
Significance of Nuclear Morphometry in Salivary Gland Neoplasms: A Cross-sectional Study
Authors: Yeduguri Jahnavi Reddy , Raju Kalyani , Mohiyuddin Azeem SM
Published: June 2023

Introduction: Fine Needle Aspiration Cytology (FNAC) is one of the commonest and most efficient investigation done for salivary gland swellings, which is of much help in diagnosing inflammatory, benign and malignant lesions. The morphology of nucleus determines the behaviour of the cell/tissue as benign or malignant. Nuclear morphometry analysis is done by using various software. Aim: To determine the nuclear morphometry parameters in salivary gland neoplasm of FNAC smears by Image J software and to determine its association with the cytological diagnosis. Materials and Methods: This was a retrospective laboratory observational cross-sectional study done for four years (2018- 2021) at a tertiary healthcare centre, attached to Sri DevarajUrs Medical College, Kolar, Karnataka, India. All the FNAC smears of salivary gland neoplasms were considered and classified by cytomorphology as benign and malignant tumours. All smears were analysed using Image J software for nuclear morphometric parameters such as area of the nucleus, perimeter of the nucleus, feret diameter, minimum ferret and skewness. The nuclear morphometric findings of benign and malignant tumours were compared and statistical analysis was doneby using Student’s t-test, p-value of <0.05 was considered statistically significant. Results: A total of 52 cases were studied. The average age of presentation of benign and malignant salivary gland neoplasm was 38.7 and 49.4 years, respectively. Among, 30 (57.6%) benign neoplasms there were 23 (76.7%), pleomorphic adenoma was the commonest and among 22 (42.4%) malignant squamous cell carcinoma 16 (72.7%) deposits was the commonest. The nuclear morphometry analysis showed that the mean values of area (p-value ≤0.001), perimeter (p-value≤0.001), ferret diameter (p-value≤0.001) and minimum ferret (p-value=0.001) of malignant lesions were comparatively higher than benign and was statistically significant. Conclusion: Nuclear morphometry along with routine cytopathological evaluation will improve the accuracy of diagnosis of neoplastic lesions of salivary gland. This information can be used to plan better treatment and predict prognosis of the disease. Digital morphological analysis helps in obtaining quantitative values from qualitative data which can be utilised further for automation.
Prevalence of Anaemia and its Association with Severity of COVID-19 among Hospitalised Patients: A Cross-sectional Study
Authors: Ghosh Anirban , Sengupta Rimi Som , Mallick Debjani , Sarkar Anirban , Chakraborty Samir
Published: June 2023

Introduction: Coronavirus Disease-2019 (COVID-19) emerged as a global pandemic and was associated with various haematologic abnormalities. There are very few studies from India regarding the association between anaemia and disease severity of COVID-19. Aim: To check the prevalence of anaemia and its association with severity of disease among hospitalised COVID-19 patients. Materials and Methods: This was a cross-sectional study involving 203 patients admitted in general ward and Intensive Care Unit (ICU) of a tertiary care hospital in eastern India. Complete blood count at admission along with other relevant clinical and laboratory parameters was noted. Haematological parameters of the patients were described and then correlated with disease severity and death. Spearman’s correlation and Chi-square test were used to determine the associations. Results: Out of 203 patients with COVID-19,145 (71.4%) had anaemia. The study included 107 males (52.7%) and 96 females (47.3%), of which 77 (80%) females had anaemia compared to 68 (63.5%) males. Co-morbidities were present in 73 patients. Haemoglobin levels were significantly negatively correlated with disease severity (p<0.001). This was even true for patients without any other co-morbidities (p<0.05). Haemoglobin was also negatively correlated with deaths in this study (p<0.05). Conclusion: The prevalence of anaemia in admitted patients of COVID-19 was very high and low haemoglobin levels were associated with more severe disease and death. So, low haemoglobin levels in COVID-19 may be considered as a risk factor for more severe disease and death.