bluuebunny/crossref_metadata_2025 huggingface dataset:
Differences in antigenic sites and other functional regions between genotype A and G mumps virus surface proteins
Authors: Gouma Sigrid , Vermeire Tessa , Van Gucht Steven , Martens Lennart , Hutse Veronik , Cremer Jeroen , Rota Paul A. , Leroux-Roels Geert , Koopmans Marion , van Binnendijk Rob , Vandermarliere Elien
Published: August 2018

The surface proteins of the mumps virus, the fusion protein (F) and haemagglutinin-neuraminidase (HN), are key factors in mumps pathogenesis and are important targets for the immune response during mumps virus infection. We compared the predicted amino acid sequences of the F and HN genes from Dutch mumps virus samples from the pre-vaccine era (1957–1982) with mumps virus genotype G strains (from 2004 onwards). Genotype G is the most frequently detected mumps genotype in recent outbreaks in vaccinated communities, especially in Western Europe, the USA and Japan. Amino acid differences between the Jeryl Lynn vaccine strains (genotype A) and genotype G strains were predominantly located in known B-cell epitopes and in N-linked glycosylation sites on the HN protein. There were eight variable amino acid positions specific to genotype A or genotype G sequences in five known B-cell epitopes of the HN protein. These differences may account for the reported antigenic differences between Jeryl Lynn and genotype G strains. We also found amino acid differences in and near sites on the HN protein that have been reported to play a role in mumps virus pathogenesis. These differences may contribute to the occurrence of genotype G outbreaks in vaccinated communities.
Low Gilbert Damping Constant in Perpendicularly Magnetized W/CoFeB/MgO Films with High Thermal Stability
Authors: Lattery Dustin M. , Zhang Delin , Zhu Jie , Hang Xudong , Wang Jian-Ping , Wang Xiaojia
Published: August 2018

Perpendicular magnetic materials with low damping constant and high thermal stability have great potential for realizing high-density, non-volatile, and low-power consumption spintronic devices, which can sustain operation reliability for high processing temperatures. In this work, we study the Gilbert damping constant (α) of perpendicularly magnetized W/CoFeB/MgO films with a high perpendicular magnetic anisotropy (PMA) and superb thermal stability. The α of these PMA films annealed at different temperatures (Tann) is determined via an all-optical Time-Resolved Magneto-Optical Kerr Effect method. We find that α of these W/CoFeB/MgO PMA films decreases with increasing Tann, reaches a minimum of α = 0.015 at Tann = 350 °C, and then increases to 0.020 after post-annealing at 400 °C. The minimum α observed at 350 °C is rationalized by two competing effects as Tann becomes higher: the enhanced crystallization of CoFeB and dead-layer growth occurring at the two interfaces of the CoFeB layer. We further demonstrate that α of the 400 °C-annealed W/CoFeB/MgO film is comparable to that of a reference Ta/CoFeB/MgO PMA film annealed at 300 °C, justifying the enhanced thermal stability of the W-seeded CoFeB films.
Author Correction: Dynamic changes in Japan’s prevalence of abnormal findings in cervical cytology depending on birth year
Authors: Ueda Yutaka , Yagi Asami , Nakayama Tomio , Hirai Kei , Ikeda Sayaka , Sekine Masayuki , Miyagi Etsuko , Enomoto Takayuki
Published: August 2018

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
The transcription factor SoxD controls neuronal guidance in the Drosophila visual system
Authors: Contreras Esteban G. , Palominos Tomás , Glavic Álvaro , Brand Andrea H. , Sierralta Jimena , Oliva Carlos
Published: August 2018

Precise control of neurite guidance during development is essential to ensure proper formation of neuronal networks and correct function of the central nervous system (CNS). How neuronal projections find their targets to generate appropriate synapses is not entirely understood. Although transcription factors are key molecules during neurogenesis, we do not know their entire function during the formation of networks in the CNS. Here, we used the Drosophila melanogaster optic lobe as a model for understanding neurite guidance during development. We assessed the function of Sox102F/SoxD, the unique Drosophila orthologue of the vertebrate SoxD family of transcription factors. SoxD is expressed in immature and mature neurons in the larval and adult lobula plate ganglia (one of the optic lobe neuropils), but is absent from glial cells, neural stem cells and progenitors of the lobula plate. SoxD RNAi knockdown in all neurons results in a reduction of the lobula plate neuropil, without affecting neuronal fate. This morphological defect is associated with an impaired optomotor response of adult flies. Moreover, knocking down SoxD only in T4/T5 neuronal types, which control motion vision, affects proper neurite guidance into the medulla and lobula. Our findings suggest that SoxD regulates neurite guidance, without affecting neuronal fate.
Mn-induced Ferromagnetic Semiconducting Behavior with Linear Negative Magnetoresistance in Sr4(Ru1−xMnx)3O10 Single Crystals
Authors: Xing Lingyi , Gui Xin , Xie Weiwei , Cao Huibo , Yan Jiaqiang , Sales Brian C. , Jin Rongying
Published: August 2018

Triple-layered Sr4Ru3O10 is a unique ferromagnet with the central RuO6 layer behaving differently from two outer layers both crystallographically and magnetically. We report that the partial substitution of Ru by smaller Mn gives rise to modification in crystal structure, electronic and magnetic properties of Sr4(Ru1−xMnx)3O10. Through the single crystal X-ray diffraction refinement, we find that (Ru/Mn)O6 octahedral rotation is no longer detectable at x ≥ 0.23, leading to the tetragonal structure. The magnetization measurements indicate the ferromagnetic transition temperature TC decreases from 105 K for x = 0 to 30 K for x = 0.41, with the reduced magnetic moment as well. Remarkably, Mn doping results in the change of magnetic anisotropy from the easy c axis in x = 0 to the easy ab plane seen in x = 0.34 and 0.41. Such change also removes the ab-plane metamagnetic transition observed in x = 0. Furthermore, the electrical resistivity increases with increasing x showing semiconducting behavior with Δ ~ 10 meV for x = 0.34 and 30 meV for x = 0.41. Under applied magnetic field, the magnetoresistance exhibits negative and linear field dependence in all current and field configurations. These results clearly indicate Sr4(Ru1−xMnx)3O10 is a novel ferromagnetic semiconductor with exotic magnetotransport properties.
The quaternary structure of Thermus thermophilus aldehyde dehydrogenase is stabilized by an evolutionary distinct C-terminal arm extension
Authors: Hayes Kevin , Noor Mohamed , Djeghader Ahmed , Armshaw Patricia , Pembroke Tony , Tofail Syed , Soulimane Tewfik
Published: August 2018

Aldehyde dehydrogenases (ALDH) form a superfamily of dimeric or tetrameric enzymes that catalyze the oxidation of a broad range of aldehydes into their corresponding carboxylic acids with the concomitant reduction of the cofactor NAD(P) into NAD(P)H. Despite their varied polypeptide chain length and oligomerisation states, ALDHs possess a conserved architecture of three domains: the catalytic domain, NAD(P)+ binding domain, and the oligomerization domain. Here, we describe the structure and function of the ALDH from Thermus thermophilus (ALDHTt) which exhibits non-canonical features of both dimeric and tetrameric ALDH and a previously uncharacterized C-terminal arm extension forming novel interactions with the N-terminus in the quaternary structure. This unusual tail also interacts closely with the substrate entry tunnel in each monomer providing further mechanistic detail for the recent discovery of tail-mediated activity regulation in ALDH. However, due to the novel distal extension of the tail of ALDHTt and stabilizing termini-interactions, the current model of tail-mediated substrate access is not apparent in ALDHTt. The discovery of such a long tail in a deeply and early branching phylum such as Deinococcus-Thermus indicates that ALDHTt may be an ancestral or primordial metabolic model of study. This structure provides invaluable evidence of how metabolic regulation has evolved and provides a link to early enzyme regulatory adaptations.
Route towards extreme optical pulsation in linear cavity ultrafast fibre lasers
Authors: Akosman Ahmet E. , Sander Michelle Y.
Published: August 2018

Pathways towards the generation of extreme optical pulsation in a chaotic transition regime in a linear fibre laser cavity configuration are presented. In a thulium mode-locked fibre laser, extreme events that can be controllably induced by manipulating the cavity birefringence for pulse energies exceeding the single soliton pulse operating regime are studied in detail for the first time. While a solitonic pulsation structure at the fundamental repetition rate is maintained, additional energy is shed in a chaotic manner, leading to broader spectral generation and shorter pulse durations whose behaviour deviates significantly from a classical statistical distribution. These pulses display markedly different characteristics from any previously reported extreme events in fibre lasers associated with multiple solitons and pulse bunching, thus presenting a novel observation of extreme pulsation. Detailed noise studies indicate that significant enhancement of relaxation oscillations, modulation instability and the interplay with reabsorption mechanisms contribute in this transient chaotic regime. The extreme pulsation generated in a compact fibre laser without any additional nonlinear attractors can provide an attractive platform to accelerate the exploration of the underlying physics of the chaos observed in mode-locked laser systems and can lead to novel fibre laser cavity designs.
Low-dimensional Models for Simulating Attosecond Processes in Atoms and Molecules
Authors: Caillat Jérémie , Maquet Alfred , Risoud François , Taïeb Richard
Published: August 2018

We present the implementation and utilisation of simple yet efficient low-dimensional models to simulate the response of atomic and molecular systems to light pulses, from the perturbative to the strong field regimes, with direct applications to attosecond sciences. The motivation is that solving the time-dependent Schrödinger equation for such simple models often proves more useful to get a clear physical picture than solving it for a full-fledged multi-dimensional model. We have focused the chapter on one- and two-dimensional approaches with illustrations on high-order harmonic generation and the photoionisation processes that are essential in an attophysics context. Within this framework, the topics we shall consider are the modelling of various aspects of high order harmonic generation in atoms and molecules (emission times, quantum path interferences, influences of the internuclear structure and dynamics) and the investigation of near threshold photoemission of a diatomic molecule with vibronic resolution from a time-dependent perspective. The advantages and limitations of low-dimensional models are discussed through the chapter.
First-principles Many-electron Dynamics Using the B-spline Algebraic Diagrammatic Construction Approach
Authors: Averbukh V. , Ruberti M.
Published: August 2018

In this chapter we present a first-principles theoretical and numerical method based on the many-electron algebraic diagrammatic construction [ADC(n)] schemes for electronic excitations, able to describe the correlated multi-electron ionisation dynamics induced in atomic and molecular systems by laser pulses both in the perturbative and non-perturbative regime. Within the ADC(n) framework, electron correlation is described at different levels of approximation depending on the specific ADC method n used within the ADC hierarchy. An accurate representation of the electronic ionisation continuum is achieved by the implementation and computational optimisation of the first- [ADC(1)] and second-order [ADC(2)] schemes in the monocentric B-spline basis set, which makes it possible to describe highly oscillatory discretised continuum wave-functions. The implementation of the time-dependent version of the B-spline ADC method is made by solving the many-electron time-dependent Schrödinger equation via the Arnoldi Lanczos algorithm. As illustrative examples we present applications of this method to the calculations of both static quantities (photoionisation cross sections of noble gas atoms) and dynamical quantities such as the high harmonic generation spectra of Ar and CO2, and the attosecond transient absorption spectrum in laser dressed He atoms.
Time-dependent Multiconfigurational Theories of Electronic and Nuclear Dynamics of Molecules in Intense Laser Fields
Authors: Kato Tsuyoshi , Yamanouchi Kaoru , Kono Hirohiko
Published: August 2018

Three multiconfigurational methods to deal with multielectron dynamics and reaction/nuclear dynamics are reviewed, together with their applications to molecules in intense fields. The first one is the multiconfiguration time-dependent Hartree–Fock method for multielectron dynamics of atoms and molecules, where the many-electron wave function is expressed as a linear combination of Slater determinants for different electron configurations. The anisotropic near-infrared induced ionization of a CO molecule is analyzed in terms of the effective potentials for natural orbitals. The second one is the time-dependent adiabatic state approach where the eigenfunctions of the instantaneous electronic Hamiltonian including the dipole interaction with an electric filed are used as expansion bases for nuclear dynamics. The method is applied to reveal the dynamics of various molecules in intense fields such as bond selective dissociation of C2H5OH. The third one is an extended multiconfiguration theory for a whole system consisting of electrons and nuclei. This method can yield the electro-protonic wave function of a hydrogen-containing molecule, such as CH3OH, that satisfies particle statistics of indistinguishable protons.
Light-induced Conical Intersections
Authors: Csehi A. , HalÁsz G. J. , Cederbaum L. S. , VibÓk Á.
Published: August 2018

When exposing molecules to resonant laser light, a new feature emerges. This feature is a conical intersection induced by the light, which cannot be avoided even in the case of diatomic molecules. The angle θ between the laser polarization and the molecular axis becomes the missing dynamical variable that, together with the stretching coordinate, establish the space in which the induced conical intersection (called the “light-induced conical intersection”, LICI) can exist. In contrast to natural CIs, which are ubiquitous in polyatomic systems and hard to manipulate, the light-induced conical intersections can easily be steered. Their positions can be controlled by the laser frequency, while the laser intensity determines the strength of the nonadiabatic coupling. The presence of a LICI in a molecular system provides a source for numerous static and dynamic nonadiabatic phenomena. Among others the LICI has a strong impact on the spectroscopic and dynamical properties of diatomic molecules. Motivated by recent theoretical works, several subjects are reviewed and analyzed showing that the LICI in diatomics gives rise to a variety of nonadiabatic phenomena.
Attophotochemistry: Coherent Electronic Dynamics and Nuclear Motion
Authors: Ajay J. S. , Komarova K. G. , Van Den Wildenberg S. , Remacle F. , Levine R. D.
Published: August 2018

We describe and discuss the theoretical methodology we use to analyze and predict novel chemical phenomena made possible by attosecond electronic excitation. We describe the dynamics by solving the time dependent Schrödinger equation with the laser pulse treated exactly as part of the Hamiltonian. We include the explicit onset of the nuclear motion following such an ultrafast excitation. The coupling to the nuclei is discussed when using either an adiabatic or a diabatic basis for the electronic dynamics. We begin by analyzing the chemical physics that can be realized by such an ultrafast excitation. Driving chemical reactions specifically towards new channels by selective attosecond excitation is explored as well as the physical parameters that can be used in such a control. Elucidating the role of other variables such as the mass is also discussed. The results are illustrated by recent applications primarily to the N2, LiH and HCN systems.
General Trajectory Surface Hopping Method for Ultrafast Nonadiabatic Dynamics
Authors: Mai Sebastian , Plasser Felix , Marquetand Philipp , González Leticia
Published: August 2018

Nonadiabatic dynamics is a central concept in the study of ultrafast chemical and physical processes, especially light-induced processes. One method to computationally study such processes is provided by the ”surface hopping including arbitrary couplings” (SHARC) approach, which we present here. We focus on a general description of the involved approximations, and the strengths and limitations of the approach. We also discuss the choice of electronic structure method and give an overview over techniques to analyze the trajectories obtained in the simulations.
Time-dependent Restricted-active-space Self-consistent-field Theory for Electron Dynamics on the Attosecond Timescale
Authors: Madsen Lars Bojer , Lévêque Camille , Omiste Juan J. , Miyagi Haruhide
Published: August 2018

The time-dependent restricted-active-space self-consistent-field (TD-RASSCF) theory is a wavefunction-based theory for the TD many-electron problem. The RAS scheme allows an inclusion of specific orbital spaces. Hence, the theory allows an identification of the spaces that are most important for a given process. The RAS reduces the configuration space, i.e., the space describing all the possible arrangements of the electrons in the different orbitals by the imposed restrictions on the excitations between orbital spaces. The use of TD SCF orbitals additionally reduces the number of configurations because the orbitals adjust in an optimal manner during time propagation. The theoretical concepts underlying the TD-RASSCF theory are discussed. A derivation of the equations of motion is presented. It is discussed how to extract observables. Some properties including gauge invariance and numerical performance are discussed. Finally some illustrative applications in high-order harmonic generation and photoionization including time-delay studies are given. The TD-RASSCF theory is a many-electron theory that accounts for correlation between the electrons, and its evaluation is, accordingly, numerically demanding. Therefore, at present, its application to strong-field many-photon processes is restricted to one spatial dimension. For calculations in three spatial dimensions, application is best suited for few-photon processes in attosecond pulses.
Elements of Structure Retrieval in Ultrafast Electron and Laser-induced Electron Diffraction from Aligned Polyatomic Molecules
Authors: Le Anh-Thu , Centurion Martin , Lin C. D.
Published: August 2018

One of the grand goals of scientific endeavour in the 21st century is to probe and control chemical reactions and biological function in real time. Ideally, this requires tempororal resolution of few to tens of femtoseconds and spatial resolution of sub-angstroms. For gas-phase molecules, ultrafast electron diffraction (UED) and laser-induced electron diffraction (LIED) have been shown to be powerful tools where the change of atomic positions in a molecule can be extracted from the measured electron momentum spectra, thus creating a “molecular movie” that reveals the molecular dynamics in real time. In this chapter we address the structure retrieval methods for both UED and LIED, especially for diffraction images created from molecules that are partially aligned. The basic principle of the LIED and a recent experiment observing bond breaking using LIED are also illustrated.
Correlation of drug-induced and drug-related ultra-high performance liquid chromatography-mass spectrometry serum metabolomic profiles yields discovery of effective constituents of Sini decoction against myocardial ischemia in rats
Authors: Tan Guangguo , Wang Xin , Liu Kui , Dong Xin , Liao Wenting , Wu Hong
Published: August 2018

A “system to system” strategy of correlating drug-related and drug-induced UHPLC-Q-TOFMS serum metabolomic profiles was developed to screen effective constituents.
Lactoferrin-conjugated pH and redox-sensitive polymersomes based on PEG-S-S-PLA-PCL-OH boost delivery of bacosides to the brain
Authors: Goyal Kritika , Konar Arpita , Kumar B. S. Hemanth , Koul Veena
Published: August 2018

In the present study, engineered lactoferrin (Lf)-conjugated pH and redox-sensitive polymersomes derived from the triblock copolymer polyethylene glycol-S-S-polylactic acid-polycaprolactone (PEG-S-S-PLA-PCL-OH) have been used to deliver bacosides to the brain.
Singlet fission in self-assembled PDI nanocrystals
Authors: Schierl Christoph , Niazov-Elkan Angelica , Shimon Linda J. W. , Feldman Yishay , Rybtchinski Boris , Guldi Dirk M.
Published: August 2018

Upon photoexcitation, self-assembled PDI nanocrystals (S1S0) in the form of rods of 70 nm width and 1 μm length are subject to a symmetry breaking charge separation (SBCS) as the first step in the singlet fission (SF) sequence.
Tailoring the interfacial structure of colloidal “giant” quantum dots for optoelectronic applications
Authors: Zhao Haiguang , Liu Jiabin , Vidal François , Vomiero Alberto , Rosei Federico
Published: August 2018

A high photocurrent density (11 ± 0.5 mA cm−2) was obtained by tailoring the interfacial structure of colloidal core/shell/shell quantum dots.
Temperature-regulated aggregation-induced emissive self-healable hydrogels for controlled drug delivery
Authors: Wang Xuemeng , Xu Kaiyue , Yao Haicui , Chang Limin , Wang Yong , Li Wenjuan , Zhao Youliang , Qin Jianglei
Published: August 2018

Thermoresponsive copolymers TPE-[P(DMA-stat-DAA)]2 containing a tetraphenylethylene (TPE) moiety and a ketone group were synthesized.
Synthesis and investigation of new cyclic molecules using the stilbene scaffold
Authors: Tobiasz Piotr , Poterała Marcin , Jaśkowska Eliza , Krawczyk Hanna
Published: August 2018

A new approach to the synthesis of asymmetrical cyclic compounds using a stilbene scaffold has been developed.
Dielectric and relaxation properties of composites of epoxy resin and hyperbranched-polyester-treated nanosilica
Authors: Yang Guoqing , Cui Junda , Ohki Yoshimichi , Wang Deyi , Li Yang , Tao Kai
Published: August 2018

Dielectric and relaxation properties of a nanofilled epoxy composite can be effectively modified by nanofiller treatment with a terminal carboxyl hyperbranched polyester.
Study on the pyrolysis treatment of HPF desulfurization wastewater using high-temperature waste heat from the raw gas from a coke oven riser
Authors: Li Chao , Li Guoqiang , Zhang Shuting , Wang Hongyu , Wang Ying , Zhang Yongfa
Published: August 2018

The thermogravimetric TG and single riser of industrial 4.3 m coke oven were used as pyrolysis reactors to study the new technology of pyrolysis treating desulfurization wastewater by waste heat solution of coke-oven raw gas.
Design and synthesis of a 4-aminoquinoline-based molecular tweezer that recognizes protoporphyrin IX and iron(iii) protoporphyrin IX and its application as a supramolecular photosensitizer
Authors: Hisamatsu Yosuke , Umezawa Naoki , Yagi Hirokazu , Kato Koichi , Higuchi Tsunehiko
Published: August 2018

A 4-aminoquinoline-based molecular tweezer was developed as a synthetic receptor for protoporphyrin IX and iron(iii) protoporphyrin IX, and applied as a supramolecular photosensitizer.
Chemoenzymatic synthesis of glycopeptides bearing rare N-glycan sequences with or without bisecting GlcNAc
Authors: Yang Weizhun , Ramadan Sherif , Orwenyo Jared , Kakeshpour Tayeb , Diaz Thomas , Eken Yigitcan , Sanda Miloslav , Jackson James E. , Wilson Angela K. , Huang Xuefei
Published: August 2018

A glycopeptide bearing a bisecting glucosamine, a rare N-glycan branch, and two LewisXtrisaccharides was synthesized for the first time.
Investigation of photocurrents resulting from a living unicellular algae suspension with quinones over time
Authors: Longatte Guillaume , Sayegh Adnan , Delacotte Jérôme , Rappaport Fabrice , Wollman Francis-André , Guille-Collignon Manon , Lemaître Frédéric
Published: August 2018

Quinones are dual compounds able to extract photosynthetic electrons from living organisms but with long-term poisoning effects.
On-demand quantitative SERS bioassays facilitated by surface-tethered ratiometric probes
Authors: Zhang Kun , Wang Yuning , Wu Meiling , Liu Yujie , Shi Dongyun , Liu Baohong
Published: August 2018

A robust chip-based SERS concept for quantitative on-demand metabolite screening is established.
Magnetic fields in Bok globules: multi-wavelength polarimetry as tracer across large spatial scales
Authors: Jorquera S. , Bertrang G. H.-M.
Published: August 2018

Context. The role of magnetic fields in the process of star formation is a matter of continuous debate. Clear observational proof of the general influence of magnetic fields on the early phase of cloud collapse is still pending. In an earlier study on Bok globules with simple structures, we find strong indications of dominant magnetic fields across large spatial scales.

Aims. The aim of this study is to test the magnetic field influence across Bok globules with more complex density structures.

Methods. We apply near-infrared polarimetry to trace the magnetic field structure on scales of 104–105 au (~0.05–0.5pc) in selected Bok globules. The combination of these measurements with archival data in the optical and sub-mm wavelength range allows us to characterize the magnetic field on scales of 103–106 au (~0.005–5pc).

Results. We present polarimetric data in the near-infrared wavelength range for the three Bok globules CB34, CB56, and [OMK2002]18, combined with archival polarimetric data in the optical wavelength range for CB34 and CB56, and in the submillimeter wavelength range for CB34 and [OMK2002]18. We find a strong polarization signal (P ≥ 2%) in the near-infrared for all three globules. For CB34, we detect a connection between the structure on scales of 104–105 au (~0.05–0.5pc) to 105–106 au (~0.5–5pc). For CB56, we trace aligned polarization segments in both the near-infrared and optical data, suggesting a connection of the magnetic field structure across the whole globule. In the case of [OMK2002]18, we find ordered polarization structures on scales of 104–105 au (~0.05–0.5pc).

Conclusions. We find strongly aligned polarization segments on large scales which indicate dominant magnetic fields across Bok globules with complex density structures. To reconcile our findings in globules, the lowest mass clouds known, and the results on intermediate (e.g. Taurus) and more massive (e.g. Orion) clouds, we postulate a mass-dependent role of magnetic fields, whereby magnetic fields appear to be dominant on low and high mass but rather subdominant on intermediate mass clouds.
The XXL Survey
Authors: Ciliegi Paolo , Jurlin Nika , Butler Andrew , Delhaize Jacinta , Fotopoulou Sotiria , Huynh Minh , Iovino Angela , Smolčić Vernesa , Chiappetti Lucio , Pierre Marguerite
Published: August 2018

Context. To investigate the nature of the extragalactic radio sources, it is necessary to couple radio surveys with multiwavelength observations over large areas of the sky. The XMM-Newton Extragalactic (XXL) survey is the largest survey ever undertaken with the XMM-Newton X-ray telescope over two separate fields of 25 deg2 each (XXL-N and XXL-S). At the same time the XXL survey benefits from a wealth of ancillary data spanning from the far-ultraviolet to the mid-infrared.

Aims. In this paper we present the optical, near-infrared (NIR), and X-ray identifications of the 6287 radio sources detected in the 2.1 GHz deep radio survey down to a median rms of σ ≈ 41 μJy beam−1 obtained with the Australia Telescope Compact Array (ATCA) in the XXL-S field. The goal of this paper is to provide a multiwavelength catalogue of the counterparts of the radio sources to be used in further studies.

Methods. For the optical and NIR identification of the radio sources, we used the likelihood ratio (LR) technique, slightly modified in order to take into account the presence of a large number of relatively bright counterparts close to the radio sources. The LR technique was applied to seven optical bands (gBCS, gDec, rBCS, rDec, iBCS, iDec, zDec) and to three NIR bands (J, H, K).

Results. The ten different photometric catalogues have been combined into a single master catalogue where all the photometric information in the optical, NIR, and X-ray bands have been collected for the counterparts of the radio sources. This procedure led to the identification of optical/NIR counterparts for 4770 different radio sources (~77% of the whole radio sample), 414 of which also have an X-ray counterpart. This fraction of identification is in agreement with previous radio-optical association studies at a similar optical magnitude depth, but is relatively low in comparison to recent work conducted in other radio fields using deeper optical and NIR data.

Conclusions. The analysis of optical and NIR properties of radio sources shows that, regardless of the radio flux limit of a radio survey, the nature of the identified sources is strongly dependent on the depth of the optical/NIR used in the identification process. Only with deep enough optical/NIR data will we be able to identify a significant fraction of radio sources with red (zDec-K) counterparts whose radio emission is dominated by nuclear activity rather than starburst activity.
Quantification of Phenolic Compounds from Fadogia agrestis and Dietary Supplements using UHPLC-PDA-MS
Authors: Avula Bharathi , Bae Ji-Yeong , Raman Vijayasankar , Fantoukh Omer , Wang Yan-Hong , Osman Ahmed , Wang Mei , Ali Zulfiqar , Khan Ikhlas
Published: August 2018

Fadogia agrestis is used in traditional African medicine as an analgesic and for anti-inflammatory and aphrodisiac activities. An ultra-high-performance liquid chromatography method was developed for the determination of 11 chemical constituents from roots and aerial parts of F. agrestis. The separation was achieved within 7 min by using C-18 column material and a water/acetonitrile mobile phase, both containing 0.1% formic acid gradient system with a temperature of 45 °C. The method was validated for linearity, repeatability, limits of detection, and limits of quantification. The limits of detection of phenolic compounds were found to be in the range from 0.025 to 0.1 µg/mL. The wavelengths used for quantification with the photodiode array detector were 238, 254, 291, and 325 nm. Twelve of 17 dietary supplements contained phenolic compounds in the range from 0.3 to 2.7 mg/d. The phenolic compounds were not detected in five dietary supplements. Liquid chromatography-mass spectrometry coupled with electrospray ionization interface method is described for the identification and confirmation of compounds from plant samples and dietary supplements claiming to contain F. agrestis. This method involved the use of [M + H]+ and [M + Na]+ ions in the positive mode and [M − H]− ions in the negative mode with extractive ion monitoring. The developed method is simple, economic, rapid, and especially suitable for quality control and chemical fingerprint analysis of F. agrestis.
Vasopressin-Induced Ventricular Arrhythmia
Authors: Ghanta Soma , Parvathaneni Sarada , Koduru Gopala , Palaparthi Sudarshan , Palaparthi Raghuram , Rao Kondru Purna
Published: August 2018

Long QT and ventricular tachyarrhythmias can occur due to a number of causes including dyselectrolytemia, drugs, and intracranial lesions, predominantly subarachnoid hemorrhage. Here the authors report a rare case of acquired long QT with R on T ventricular ectopics due to vasopressin in the setting of intracerebral bleed, which reverted on withdrawal of vasopressin.
Endovascular Management of Cerebral Aneurysm: The Recent Trends
Authors: Gupta Vipul , Londhe Shrikant , Parthasarathy Rajsrinivas , Ganaie Hilal
Published: August 2018

Cerebral aneurysm rupture is the leading cause of mortality and morbidity in patients with hemorrhagic stroke. Surgical clipping and endovascular coiling are the mainstay of management for securing the aneurysm. After International Subarachnoid Aneurysm Trial (ISAT) and Barrow Ruptured Aneurysm Trial (BRAT) results, worldwide trend has shifted gradually in favor of endovascular management. Nonetheless, endovascular management was faced with some limitations, especially while treating giant, wide neck bifurcation, blister, and small uncoilable aneurysm. The recent introduction of new devices such as flow diverter stents, microstents, bifurcation devices, double-lumen balloon catheters, and microcoils have proved to be effective in overcoming the limitations of traditional aneurysm coiling. The authors present a review of recent advances in the endovascular management of cerebral aneurysm.
Conservative Management of Subacute Contained Left Ventricular Rupture after Acute Myocardial Infarction
Authors: Goud C Bharat , Christopher Johann
Published: August 2018

Left ventricular free wall rupture (LVFWR) is a near-fatal mechanical complication of acute myocardial infarction in which an early diagnosis and emergency surgery should be of utmost priority for successful treatment. LVFWR is generally perceived to be universally fatal. Majority of LVFWR patients developing cardiac tamponade die rapidly, while in minority of cases the development of tamponade may be sufficiently slow to allow for diagnosis and successful intervention. In this article, the authors report a case of a 63-year-old male patient diagnosed with an inferoposterior wall myocardial infarction treated with early reperfusion thrombolytic therapy presenting 3 days later with diagnosis of subacute LVFWR. Patient had a history of relapse of chest pain which was severe and prolonged with 2 to 3 mm saddle-shaped ST-segment elevation in lateral leads, detected on a routine electrocardiogram, which led to an urgent bedside transthoracic echocardiogram (TTE). TTE showed regional wall motion abnormality in form of akinetic basal inferior-wall, a small echodense pericardial effusion, and a canalicular tract from endocardium to pericardium, through which color-Doppler examination suggested blood crossing the myocardial wall. A cardiac magnetic resonance imaging further reinforced the possibility of contained LVFWR.
Hydrostatic findings reveal new features of 2-D hybrid organic-inorganic perovskites
Authors: Liebendorfer Adam
Published: August 2018

Work on two-dimensional benzylammonium lead bromide shows anisotropic elasticity accompanied by a significant red shift and decrease in photoluminescence when under pressure.
NMR screening and studies of target – ligand interactions
Authors: Polshakov Vladimir I. , Batuev Evgeniy A. , Mantsyzov Alexey B.
Published: August 2018

Nuclear magnetic resonance (NMR) spectroscopy is one of the leading biophysical methods used in the search for and design of physiologically active compounds considered as potential drugs. The review concerns modern NMR techniques used to study the binding of low-molecular-mass compounds to biomacromolecular targets. The most promising methods of NMR screening and strategies for rational lead design are discussed. They were used to design drugs that have been approved for the use in medical practice or are in the final stages of clinical trials. Examples are given of the application of the fragment-based drug design and NMR screening techniques to the design of novel drugs.

The bibliography includes 252 references.
Values of the public at risk of wildfire and its management
Authors: Williams Kathryn J. H. , Ford Rebecca M. , Rawluk Andrea
Published: August 2018

Wildfire management agencies increasingly seek to understand what the public values and expects to be protected from wildfire and its management. Recent conceptual development demonstrates the utility of considering values at three levels of abstraction: localised valued entities such as people, places and objects; valued attributes of communities and landscapes; and core values, or ideals that guide in life. We used a large-scale survey (n = 1105) in Victoria, Australia, to test and extend this framework. The results confirm the usefulness of the conceptual framework and demonstrate that values that members of the public consider at risk of wildfire are much more diverse than those typically considered in wildfire risk management. Relationships between values at different levels of abstraction are meaningful and reveal the multiple ways that objects, places and people become valued. The research suggests ways to understand and practically incorporate values of the public in wildfire management.
Tribological behaviour of textured titanium under abrasive wear
Authors: Li Xingliang , Yue Wen , Huang Fei , Kang Jiajie , Zhu Lina , Tian Bin
Published: August 2018

In order to improve the tribological behaviour of titanium used in aerospace exploration. Dimple textures were prepared on a commercial pure titanium grade 2 (TA2) surface by laser surface texturing. Tribological behaviour of the textured TA2 was investigated under two kinds of simulated lunar soil particles in dry sliding contact. The tribological mechanisms were analysed using NanoMap-D 3D surface profilometer, scanning electron microscope and energy-dispersive spectroscopy. An orthogonal analysis was used to study the influence of dimple parameters on anti-friction and anti-wear performances. The result showed that the textured titanium surface exhibited a better anti-friction and anti-wear performance under the small particle wearing condition compared with that under the large particle. The dimple density had a remarkable effect on both the anti-friction and anti-wear performances under small particle wear, while it became weaker under large particle wear. The dimple depth had almost no effect on the tribological behaviour.
Nuclear rupture at sites of high curvature compromises retention of DNA repair factors
Authors: Xia Yuntao , Ivanovska Irena L. , Zhu Kuangzheng , Smith Lucas , Irianto Jerome , Pfeifer Charlotte R. , Alvey Cory M. , Ji Jiazheng , Liu Dazhen , Cho Sangkyun , Bennett Rachel R. , Liu Andrea J. , Greenberg Roger A. , Discher Dennis E.
Published: August 2018

The nucleus is physically linked to the cytoskeleton, adhesions, and extracellular matrix—all of which sustain forces, but their relationships to DNA damage are obscure. We show that nuclear rupture with cytoplasmic mislocalization of multiple DNA repair factors correlates with high nuclear curvature imposed by an external probe or by cell attachment to either aligned collagen fibers or stiff matrix. Mislocalization is greatly enhanced by lamin A depletion, requires hours for nuclear reentry, and correlates with an increase in pan-nucleoplasmic foci of the DNA damage marker γH2AX. Excess DNA damage is rescued in ruptured nuclei by cooverexpression of multiple DNA repair factors as well as by soft matrix or inhibition of actomyosin tension. Increased contractility has the opposite effect, and stiff tumors with low lamin A indeed exhibit increased nuclear curvature, more frequent nuclear rupture, and excess DNA damage. Additional stresses likely play a role, but the data suggest high curvature promotes nuclear rupture, which compromises retention of DNA repair factors and favors sustained damage.
Bristol and West Building Society v Mothew [1998] Ch 1, Court of Appeal
Authors: Whayman Derek
Published: August 2018

Essential Cases: Equity & Trusts provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Bristol and West Building Society v Mothew [1998] Ch 1, Court of Appeal. The document also includes supporting commentary from author Derek Whayman.
Co-operative Insurance Society Ltd v Argyll Stores (Holdings) Ltd [1998] AC 1, House of Lords
Authors: Whayman Derek
Published: August 2018

Essential Cases: Equity & Trusts provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Co-operative Insurance Society Ltd v Argyll Stores (Holdings) Ltd [1998] AC 1, House of Lords. The document also includes supporting commentary from author Derek Whayman.
Nestlé v National Westminster Bank Plc [1993] 1 WLR 1260, Court of Appeal
Authors: Whayman Derek
Published: August 2018

Essential Cases: Equity & Trusts provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Nestlé v National Westminster Bank Plc [1993] 1 WLR 1260, Court of Appeal. The document also includes supporting commentary from author Derek Whayman.
Patel v Mirza [2017] AC 467, Supreme Court
Authors: Whayman Derek
Published: August 2018

Essential Cases: Equity & Trusts provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Patel v Mirza [2017] AC 467, Supreme Court. The document also includes supporting commentary from author Derek Whayman.
Cambridge Water Co v Eastern Counties Leather plc [1994] 2 AC 264
Authors: Purshouse Craig
Published: August 2018

Essential Cases: Tort Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Cambridge Water Co v Eastern Counties Leather plc [1994] 2 AC 264. The document also included supporting commentary from author Craig Purshouse.
Home Office v Dorset Yacht Co. Ltd [1970] AC 1004
Authors: Purshouse Craig
Published: August 2018

Essential Cases: Tort Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Home Office v Dorset Yacht Co. Ltd [1970] AC 1004. The document also included supporting commentary from author Craig Purshouse.
Rothwell v Chemical & Insulating Co Ltd [2008] 1 AC 281
Authors: Purshouse Craig
Published: August 2018

Essential Cases: Tort Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Rothwell v Chemical & Insulating Co Ltd [2008] 1 AC 281. The document also included supporting commentary from author Craig Purshouse.
Krell v Henry [1903] 2 KB 740
Authors: Jackson Nicola
Published: August 2018

Essential Cases: Contract Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Krell v Henry [1903] 2 KB 740. The document also includes supporting commentary from author Nicola Jackson.
Lombard North Central plc v Butterworth [1987] QB 527
Authors: Jackson Nicola
Published: August 2018

Essential Cases: Contract Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Lombard North Central plc v Butterworth [1987] QB 527. The document also includes supporting commentary from author Nicola Jackson.
With v O’Flanagan [1936] Ch 575
Authors: Jackson Nicola
Published: August 2018

Essential Cases: Contract Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in With v O’Flanagan [1936] Ch 575. The document also includes supporting commentary from author Nicola Jackson.
Germany v Parliament and Council (‘Tobacco Advertising I’) (Case C-376/98), EU:C:2000:544, [2000] ECR I-8419, 5 October 2000
Authors: O’Meara Noreen
Published: August 2018

Essential Cases: EU Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Germany v Parliament and Council (‘Tobacco Advertising I’) (Case C-376/98), EU:C:2000:544, [2000] ECR I-8419, 5 October 2000. The document also included supporting commentary from author Noreen O’Meara.
Kunqian Catherine Zhu and Man Lavette Chen v Secretary of State for the Home Department (Case C-200/02), EU:C:2004:639, [2004] ECR I-9925, 19 October 2004
Authors: O’Meara Noreen
Published: August 2018

Essential Cases: EU Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Kunqian Catherine Zhu and Man Lavette Chen v Secretary of State for the Home Department (Case C-200/02), EU:C:2004:639, [2004] ECR I-9925, 19 October 2004. The document also included supporting commentary from author Noreen O’Meara.
Van Duyn v Home Office (Case 41/74), EU:C:1974:133, [1974] ECR 1337, 4 December 1974
Authors: O’Meara Noreen
Published: August 2018

Essential Cases: EU Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Van Duyn v Home Office (Case 41/74), EU:C:1974:133, [1974] ECR 1337, 4 December 1974. The document also included supporting commentary from author Noreen O’Meara.
Binions v Evans [1972] Ch 359, Court of Appeal
Authors: Nair Aruna
Published: August 2018

Essential Cases: Land Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Binions v Evans [1972] Ch 359, Court of Appeal. The document also includes supporting commentary from author Aruna Nair.
City of London Building Society v Flegg [1988] AC 54, House of Lords
Authors: Nair Aruna
Published: August 2018

Essential Cases: Land Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in City of London Building Society v Flegg [1988] AC 54, House of Lords. The document also includes supporting commentary from author Aruna Nair.
Mortgage Corporation v Shaire [2001] Ch 743, High Court (Chancery Division)
Authors: Nair Aruna
Published: August 2018

Essential Cases: Land Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Mortgage Corporation v Shaire [2001] Ch 743, High Court (Chancery Division). The document also includes supporting commentary from author Aruna Nair.
Thorner v Major [2009] UKHL 18, House of Lords
Authors: Nair Aruna
Published: August 2018

Essential Cases: Land Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Thorner v Major [2009] UKHL 18, House of Lords. The document also includes supporting commentary from author Aruna Nair.
DPP v Majewski [1977] AC 443, House of Lords
Authors: Herring Jonathan
Published: August 2018

Essential Cases: Criminal Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in DPP v Majewski [1977] AC 443, House of Lords. The document also included supporting commentary from author Jonathan Herring.
R v Blaue [1975] 1 WLR 1411, Court of Appeal
Authors: Herring Jonathan
Published: August 2018

Essential Cases: Criminal Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in R v Blaue [1975] 1 WLR 1411, Court of Appeal. The document also included supporting commentary from author Jonathan Herring.
Public Law
Authors: Stanton John , Prescott Craig
Published: August 2018

Public Law provides an interesting approach to constitutional and administrative law. Topics include: the UK constitution; the institutions of government and the separation of powers; the rule of law; Parliamentary sovereignty; and Parliamentary sovereignty, the European Union, and Brexit. It also looks at the Crown and the royal prerogative; central government; Parliament; and devolution and local government. Next it presents a number of judicial reviews in the following: illegality, irrationality and proportionality, and procedural impropriety. Finally, it considers administrative justice; the European Convention on Human Rights and the Human Rights Act; and human rights in the UK.