bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring the meaning of participation in a community art project: A case study on the Seeming project
Authors: Madyaningrum Monica E. , Sonn Christopher
Published: December 2010

In Australia, community art has drawn significant research attention in regard to its potential as a community development strategy. Despite the fact that researchers have presented evidence for the positive developmental outcomes of participation in community art projects, a gap remains in understanding how and why people's participation in a community art project can lead to those positive outcomes. This research explored the meaning of participation in a community art project from the vantage point of the people who experience it. Ten participants were interviewed about their participation in a community art project (The Seeming) held in Bendigo, Australia. Following thematic analyses we identified three themes of how participants viewed their participation in a community arts project. These themes included giving voice to the silenced, creation of social connections and challenging and reproducing stereotypes. Participation means coming together and the findings highlight the potential of community arts projects for promoting the creation of new relationships and new stories about community. However, there are also problematic stories about self and others that were not deconstructed. It is argued that the settings in which different groups join can be meaningfully extended if there is an explicit concern with consciousness raising and deconstruction of normative stories. Copyright © 2010 John Wiley & Sons, Ltd.
Synthesis, Evaluation, and Mechanism of N,N,N‐Trimethyl‐D‐glucosamine‐(1→4)‐chitooligosaccharides as Selective Inhibitors of Glycosyl Hydrolase Family 20 β‐N‐Acetyl‐D‐hexosaminidases
Authors: Yang You , Liu Tian , Yang Yongliang , Wu Qingyue , Yang Qing , Yu Biao
Published: December 2010

GH20 β‐N‐acetyl‐D‐hexosaminidases are enzymes involved in many vital processes. Inhibitors that specifically target GH20 enzymes in pests are of agricultural and economic importance. Structural comparison has revealed that the bacterial chitindegrading β‐N‐acetyl‐D‐hexosaminidases each have an extra +1 subsite in the active site; this structural difference could be exploited for the development of selective inhibitors. N,N,Ntrimethyl‐D‐glucosamine (TMG)‐chitotriomycin, which contains three GlcNAc residues, is a natural selective inhibitor against bacterial and insect β‐N‐acetyl‐D‐hexosaminidases. However, our structural alignment analysis indicated that the two GlcNAc residues at the reducing end might be unnecessary. To prove this hypothesis, we designed and synthesized a series of TMG‐chitotriomycin analogues containing one to four GlcNAc units. Inhibitory kinetics and molecular docking showed that TMG‐(GlcNAc)2, is as active as TMG‐chitotriomycin [TMG‐(GlcNAc)3]. The selective inhibition mechanism of TMG‐chitotriomycin was also explained.
ChemInform Abstract: The Role of Oxygen Stoichiometry on Phase Stability, Structure, and Magnetic Properties of Sr2CoIrO6‐δ.
Authors: Mikhailova D. , Narayanan N. , Gruner W. , Voss A. , Senyshyn A. , Trots D. M. , Fuess H. , Ehrenberg H.
Published: December 2010

The structural features of Sr2CoIrO6‐δ in which the oxygen deficiency can be well controlled and reversibly varied up to δ = 0.33, depend on both temperature and oxygen content and are determined by synchrotron and neutron powder diffraction.
ChemInform Abstract: Structural Study of the Li0.5Na0.5MnFe2(PO4)3 and Li0.75Na0.25MnFe2 (PO4)3 Alluaudite Phases and Their Electrochemical Properties as Positive Electrodes in Lithium Batteries.
Authors: Trad Khiem , Carlier Dany , Croguennec Laurence , Wattiaux Alain , Amara Mongi Ben , Delmas Claude
Published: December 2010

LixNa1‐xMnFe2(PO4)3 (x = 0, 0.5, 0.75) is synthesized by a sol—gel method from stoichiometric amounts of Na2CO3, Li2CO3, MnCO3, FeC2O4, and (NH4)H2PO4 in H2O containing HNO3 and citric acid (800 °C, 30 min).
ChemInform Abstract: Luminescence of Complex Ion WO18‐12 in Dy3+ Doped Nanocrystal Gd6WO12 Phosphor.
Authors: Yu Tingting , Sun Jiashi , Hua Ruinian , Cheng Lihong , Zhong Haiyang , Li Xiangping , Yu Hongquan , Chen Baojiu
Published: December 2010

Nanocrystalline Gd6WO12:Dy3+ phosphor is synthesized by coprecipitation from an aqueous solution of GdCl3, DyCl3 (molar ratio of 99:1), and Na2WO4 (pH < 12 adjusted with NH3, 30 min) followed by calcination at 900 °C for 4 h.
ChemInform Abstract: Fabrication of Apatite‐Type La9.33(SiO4)6O2 Hollow Nanoshells as Energy‐Saving Oxidative Catalysts.
Authors: Zhang Xian‐Hua , Yi Xiaodong , Zhang Jiawei , Xie Zhaoxiong , Kang Junyong , Zheng Lansun
Published: December 2010

Apatite‐type La9.33(SiO4)6O2 hollow nanoshells are prepared from an aqueous solution of La(NO3)3, trisodium citrate, and urea (autoclave, 200 °C, 8 h) followed by dispersion of the obtained precipitate in aqueous NH4OH and addition of EtOH and Si(OEt)4 (10 h).
ChemInform Abstract: High‐Pressure Synthesis and Characterization of the Fluoride Borate Tm5(BO3)2F9.
Authors: Haberer Almut , Enders Michael , Kaindl Reinhard , Huppertz Hubert
Published: December 2010

Single crystals of the title compound are obtained from a stoichiometric mixture of B2O3, Tm2O3, and TmF3 (BN crucible, 5 GPa, 900 °C, 20 min).
ChemInform Abstract: Yb3O(OH)6Cl·2H2O: An Anion‐Exchangeable Hydroxide with a Cationic Inorganic Framework Structure.
Authors: Goulding Helen V. , Hulse Sarah E. , Clegg William , Harrington Ross W. , Playford Helen Y. , Walton Richard I. , Fogg Andrew M.
Published: December 2010

The title compound is hydrothermally synthesized from an aqueous solution of YbCl3, NaCl, and NaOH (autoclave, 220 °C, 14 h).
ChemInform Abstract: Binary Bismuth(III) Azides: Bi(N3)3, [Bi(N3)4]‐, and [Bi(N3)6]3‐.
Authors: Villinger Akexander , Schulz Axel
Published: December 2010

Compounds (II) and (III) are characterized by IR and Raman spectroscopy, and compounds (IV), (V), and (VII) by single crystal XRD, 14N NMR, IR, and Raman spectroscopy.
ChemInform Abstract: Synthesis, High‐Resolution Crystal Structure Refinement and Magnetic Properties of the Manganese‐Rich Cementite‐Type Mn1.8Fe1.2C.
Authors: Stork Ludwig , Mueller Paul , Speldrich Manfred , Koegerler Paul , von Appen Joerg , Dronskowski Richard
Published: December 2010

The title compound is obtained from the elements in almost quantitative yield (1030 °C, 24 h; quenching).
ChemInform Abstract: Development of an Icosahedral Quasicrystal and Two Approximants in the Ca—Au—Sn System: Syntheses and Structural Analyses.
Authors: Lin Qisheng , Corbett John D.
Published: December 2010

The icosahedral quasicrystal Ca15Au60Sn25 (I) and the corresponding 1/1 and 2/1 approximants Ca3Au14.36Sn4.38 (II) and Ca13Au47.2Sn28.1 (III), resp., are prepared from Ca/Au/Sn mixtures (850 °C, 24 h) in the ratio of 14.5/60.1/25.4 for (I) (quenching, 90% yield), 13/67/20 for (II) (annealing at 500 °C for three weeks, 90% yield), and 15/52.5/32.5 for (III) (annealing at 400 °C for three weeks, <95% yield).
ChemInform Abstract: Monofluorinated Aziridines in Asymmetric Synthesis of Chiral Fluorinated Prop‐2‐yn‐1‐amines.
Authors: Konev A. S. , Tehrani K. Abbaspour , Khlebnikov A. F. , Novikov M. S. , Magull J.
Published: December 2010

Enantioenriched fluorinated aziridines (III), obtained by aziridination of imines (I) with fluorocarbene, undergo aziridine ring opening in the presence of potassium alkynyltrifluoroborates (V) to give optically active fluorinated ynamines (VI)/(VII).
ChemInform Abstract: Solvent‐Free Direct Enantioselective Aldol Reaction Using Polystyrene‐Supported N‐Sulfonyl‐(Ra)‐binam‐D‐prolinamide as a Catalyst.
Authors: Banon‐Caballero Abraham , Guillena Gabriela , Najera Carmen
Published: December 2010

Polystyrene‐supported binam‐prolinamide (PSBP) is used as catalyst in the aldol reaction between several ketones and aldehydes under solvent‐free or aqueous conditions affording the corresponding aldol product in high regio‐, diastereo, and enantioselectivities.
ChemInform Abstract: Electron‐Donating and Rigid P‐Stereogenic Bisphospholane Ligands for Highly Enantioselective Rhodium‐Catalyzed Asymmetric Hydrogenations.
Authors: Zhang Xiaowei , Huang Kexuan , Hou Guohua , Cao Bonan , Zhang Xumu
Published: December 2010

The new P‐stereogenic bisphospholane ligand (ZPHOS) shows high effectivity in the rhodium‐catalyzed hydrogenation of various functionalized olefins.
ChemInform Abstract: Palladium/Tris(tert‐butyl)phosphine‐Catalyzed Suzuki Cross‐Couplings in the Presence of Water.
Authors: Lou Sha , Fu Gregory C.
Published: December 2010

Commercially available KF·2H2O is used instead of anhydrous KF as inexpensive activator for the title reaction of aryl, heteroaryl, and alkenyl halides and boronic acids.
ChemInform Abstract: Polystyrene‐Supported Amino Acids as Efficient Catalyst for Chemical Fixation of Carbon Dioxide.
Authors: Qi Chaorong , Ye Jinwu , Zeng Wei , Jiang Huanfeng
Published: December 2010

Dioxolanones and oxazolidinones are prepared by treatment of epoxides or aziridines, respectively, with CO2 under neat conditions in the presence of only 0.6 mol% of polymer‐supported threonine or tyrosine.
ChemInform Abstract: Improved Microwave‐Assisted Ring Opening of 1,1,1‐Trifluoro‐2,3‐epoxypropane: Synthesis of New 3‐Alkoxy‐1,1,1‐trifluoropropan‐2‐ols.
Authors: Rayo Josep , Munoz Lourdes , Rosell Gloria , Bosch Ma. Pilar , Guerrero Angel
Published: December 2010

The products are of interest as subunits of polyfunctional bioactive molecules and as synthons of liquid crystalline molecules.
ChemInform Abstract: Asymmetric Synthesis of Functionalized, Monocyclic Chlorocyclobutenes.
Authors: Darses Benjamin , Greene Andrew E. , Poisson Jean‐Francois
Published: December 2010

Polyfunctional monocyclic chiral chlorocyclobutenes are constructed starting from the chiral stericol‐derived enol ethers and trichloroacetyl chloride.
ChemInform Abstract: Organocatalytic Asymmetric Inverse‐Electron‐Demand Diels—Alder Reaction of Electron‐Deficient Dienes and Crotonaldehyde.
Authors: Li Jun‐Long , Kang Tai‐Ran , Zhou Si‐Li , Li Rui , Wu Li , Chen Ying‐Chun
Published: December 2010

The present first organocatalytic asymmetric inverse‐electron‐demand Diels—Alder reaction of electron‐deficient dienes with crotonaldehyde gives cyclohexene derivatives with high diastereo‐ and enantioselectivity.
ChemInform Abstract: Heck Reaction Catalyzed by a Recyclable Palladium Supported on Shell Powder.
Authors: Shen Yong‐Miao , Du Yi‐Jun , Zeng Min‐Feng , Zhi Duo , Zhao Sheng‐Xian , Rong Lin‐Mei , Lv Shao‐Qin , Du Lin , Qi Chen‐Ze
Published: December 2010

A novel palladium catalyst supported on shell powder is prepared to be used in Heck reactions of various aryl iodides with olefins.
ChemInform Abstract: A General Palladium‐Catalyzed Sonogashira Coupling of Aryl and Heteroaryl Tosylates.
Authors: R'kyek Omar , Halland Nis , Lindenschmidt Andreas , Alonso Jorge , Lindemann Peter , Urmann Matthias , Nazare Marc
Published: December 2010

The present new general palladium‐catalyzed procedure for the cross‐coupling of (hetero)aryl tosylates provides a facile access to various functionalized (hetero)aryl alkynes tolerating many functional groups.
ChemInform Abstract: Formamidines — Versatile Ligands for Zinc‐Catalyzed Hydrosilylation and Iron‐Catalyzed Epoxidation Reactions.
Authors: Enthaler Stephan , Schroeder Kristin , Inoue Shigeyoshi , Eckhardt Bjoern , Junge Kathrin , Beller Matthias , Driess Matthias
Published: December 2010

Formamidine ligands, e.g. (I), are successfully applied in the Zn‐catalyzed hydrosilylation—hydrolysis reaction of a diversity of aromatic and aliphatic ketones [cf.
ChemInform Abstract: A Selective and Benign Synthesis of Functionalized Benzalacetones via Mizoroki—Heck Reaction Using Aryldiazonium Salts.
Authors: Stern Therese , Rueckbrod Sven , Czekelius Constantin , Donner Constanze , Brunner Heiko
Published: December 2010

Either Pd(OAc)2 or Pd‐C clusters generated by pre‐reduction of Pd(OAc)2 with MeOH in the presence of charcoal before starting the reaction are used as catalysts in the presence of CaCO3 as base.
ChemInform Abstract: Unexpected Reduction of N‐Hydroxyphthalimides to Phthalimides — Orthogonal Reduction of Functionalized N‐Hydroxyphthalimides.
Authors: Jacq Jerome , Berthiol Florian , Einhorn Cathy , Einhorn Jacques
Published: December 2010

Since the attempt to borylate starting compound (I) at the iodo function fails and loss of the N‐hydroxy group is observed instead, the conditions are optimized and applied to the reduction of various N‐hydroxyphthalimide derivatives.
ChemInform Abstract: Chiral Phosphoric Acid Catalyzed Peroxidation of Imines.
Authors: Zheng Wenhua , Wojtas Lukasz , Antilla Jon C.
Published: December 2010

The title reaction provides direct access to α‐amino peroxides with high enantioselectivity using the phosphoric acid catalyst CPAB which activates both the nucleophile and electrophile by hydrogen‐bonding interactions.
ChemInform Abstract: TAPC‐Promoted Oxidation of Sulfides and Deoxygenation of Sulfoxides.
Authors: Bahrami Kiumars , Khodaei Mohammad M. , Arabi Mehdi Sheikh
Published: December 2010

Treatment of sulfides with H2O2 and TAPC allows rapid, efficient, and selective access to either sulfoxides or sulfones.
ChemInform Abstract: A Novel Synthesis of N‐Unsubstituted β‐Enamino Thioesters from 3‐Arylisoxazoles and 3‐Aryl‐5‐phenylthio‐2‐isoxazolines.
Authors: Vitale Paola , Di Nunno Leonardo , Scilimati Antonio
Published: December 2010

The base‐mediated conversion of isoxazolines (I) and isoxazoles (III) into target compounds (II) is accompanied by the formation of several side products.
ChemInform Abstract: Zinc Chloride Enhanced Arylations of Secondary Benzyl Trifluoroacetates in the Presence of β‐Hydrogen Atoms.
Authors: Duan Hui , Meng Lingkui , Bao Denghui , Zhang Heng , Li Yao , Lei Aiwen
Published: December 2010

Arylation of benzyl trifluoroacetates with arylzinc reagents proceeds in the presence of β‐hydrogen atoms under mild conditions without any palladium catalysts.
ChemInform Abstract: Periselectivity Switch of Acylketenes in Cycloadditions with 1‐Azadienes: Microwave‐Assisted Diastereoselective Domino Three‐Component Synthesis of α‐Spiro‐δ‐lactams.
Authors: Presset Marc , Coquerel Yoann , Rodriguez Jean
Published: December 2010

A variety of α‐spiro‐δ‐lactams is prepared selectively via an imination/Wolff rearrangement/[4 + 2]‐cycloaddition sequence.
ChemInform Abstract: Efficient Catalytic Corey—Chaykovsky Reactions Involving Ketone Substrates.
Authors: Kavanagh Sarah A. , Piccinini Alessandro , Connon Stephen J.
Published: December 2010

Aromatic and aliphatic ketones are converted into terminal epoxides by treatment with methyl triflate in the presence of tetrahydrothiophene as catalyst and a phosphazene base.
ChemInform Abstract: Pd(II)‐Catalyzed Hydroxyl‐Directed C—H Activation/C—O Cyclization: Expedient Construction of Dihydrobenzofurans.
Authors: Wang Xisheng , Lu Yi , Dai Hui‐Xiong , Yu Jin‐Quan
Published: December 2010

Intramolecular cyclization of tertiary phenylethanol derivatives, e.g. (I), (III) or (V), proceeds smoothly in the presence of Pd(II) catalyst and Ph‐I(O‐Ac)2 to give dihydrobenzofuran derivatives in good yields.
ChemInform Abstract: A Concise Silylamine Approach to 2‐Amino‐3‐hydroxy‐indoles with Potent in vivo Antimalaria Activity.
Authors: Urgaonkar Sameer , Cortese Joseph F. , Barker Robert H. , Cromwell Mandy , Serrano Adelfa E. , Wirth Dyann F. , Clardy Jon , Mazitschek Ralph
Published: December 2010

The target compounds are prepared from isatins in two steps by using tert‐butyldimethylsilyl amine as an ammonia equivalent.
ChemInform Abstract: Pd‐Catalyzed Asymmetric aza‐Wacker‐Type Cyclization Reaction of Olefinic Tosylamides.
Authors: Jiang Feng , Wu Zhengxing , Zhang Wanbin
Published: December 2010

Optimized conditions afford dihydroindoles (III) with up to 74% e.e.
ChemInform Abstract: Synthesis of 3,3‐Diindolyl Oxyindoles Efficiently Catalyzed by FeCl3 and Their in vitro Evaluation for Anticancer Activity.
Authors: Kamal Ahmed , Srikanth Y. V. V. , Khan M. Naseer A. , Shaik Thokhir Basha , Ashraf Md.
Published: December 2010

Compound (IIIb) exhibits potent cytotoxicity against SK‐N‐SH and DU‐145 human cancer cell lines, whereas compounds (IIIc)—(IIIe) and (Vc) exhibit potent cytotoxicity against the DU‐145 cell line.
ChemInform Abstract: Copper(II) Chloride Catalyzed Friedel—Crafts‐Type Conjugate Addition of Indoles to α,β‐Unsaturated Enones: Synthesis of 3‐Substituted Indoles.
Authors: Kanwar Deepika , Rani Rashmi , Agarwal Jyoti , Peddinti Rama Krishna
Published: December 2010

The substitution occurs exclusively at the 3‐position of indoles and N‐alkylation products are not observed.
ChemInform Abstract: Palladium‐Catalyzed Double Carbonylation Reactions of o‐Dihaloarenes with Amines in Phosphonium Salt Ionic Liquids.
Authors: Cao Hong , Alper Howard
Published: December 2010

N‐Substituted phthalimides are prepared in phosphonium salt ionic liquid CYPHOSIL 102 as a solvent.
ChemInform Abstract: Synthesis of 2‐Aminobenzothiazole via FeCl3‐Catalyzed Tandem Reaction of 2‐Iodoaniline with Isothiocyanate in Water.
Authors: Ding Qiuping , Cao Banpeng , Liu Xianjin , Zong Zhenzhen , Peng Yi‐Yuan
Published: December 2010

An environmentally benign, efficient, and general route for the synthesis of 2‐aminobenzothiazole derivatives is developed.
ChemInform Abstract: Hypervalent Iodine(III) Mediated Synthesis of Novel Unsymmetrical 2,5‐Disubstituted 1,3,4‐Oxadiazoles as Antibacterial and Antifungal Agents.
Authors: Prakash Om , Kumar Manoj , Kumar Rajesh , Sharma Chetan , Aneja K. R.
Published: December 2010

A series of 11 title compounds of type (IV) is evaluated for their antibacterial and antifungal activities.
ChemInform Abstract: Synthesis and Biological Property of Some Novel 1,3,4‐Oxadiazoles.
Authors: Ramaprasad G. C. , Kalluraya Balakrishna , Kumar B. Sunil , Hunnur Ravindra K.
Published: December 2010

Newly synthesized oxadiazoles (VI) and (VII) are screened for biological activities.
ChemInform Abstract: A Simple Method for the Synthesis of Functionalized 6‐Aryl‐6H‐dibenzo[b,d]pyran Derivatives from 3‐Nitro‐2H‐chromenes.
Authors: Li Ping , Luo Ling‐Ling , Li Xin‐Sheng , Xie Jian‐Wu
Published: December 2010

A domino vinylogous Michael addition—cyclization reaction of nitrochromenes (I) and (VI) with α,α‐dicyanoolefins is readily achieved in the presence of base Et3N to give functionalized dibenzopyran derivatives in moderate yields.
ChemInform Abstract: Synthesis of 3‐Amino‐2,2‐dimethyl‐8‐thia‐1‐azaspiro[4.5]decane.
Authors: Mai Wenpeng , Green Sarah A. , Bates Dallas K. , Fang Shiyue
Published: December 2010

Key steps in the synthesis of the title compound (VII) are the prenyl‐group introduction and a iodine‐initiated aminocyclization to form the azaspirocycle.
ChemInform Abstract: One‐Pot Synthesis of Quinoline Derivatives Directly from Terminal Alkynes via Sequential Ruthenium(II) and Acid Catalysis.
Authors: Zhang Min , Roisnel Thierry , Dixneuf Pierre H.
Published: December 2010

The method is based on the head‐to‐head oxidative coupling of terminal alkynes to give allylic ketones, which undergo a cyclization with aniline derivatives to give the target quinolines.
ChemInform Abstract: Synthesis and Antimicrobial Activity of 1‐Alkyl and Aryl‐3‐(2‐methyl‐1,8‐naphthyridin‐3‐yl)ureas.
Authors: Ramesh D. , Chary M. Thirumala , Laxminarayana E. , Sreenivasulu B.
Published: December 2010

Curtius rearrangement of azides (II) leads to title naphthyridin‐3‐yl ureas (IV) which are screened for antifungal activity against Alternaria alternata, Fusarium oxysporum, and Curvularia lunata.
ChemInform Abstract: Refinement of the Pharmacophore of 3,4‐Dihydroquinazoline‐2(1H)‐thiones for Their anti‐Melanogenesis Activity.
Authors: Thanigaimalai Pillaiyar , Sharma Vinay K. , Lee Ki‐Cheul , Yun Cheong‐Yong , Kim Youngsoo , Jung Sang‐Hun
Published: December 2010

In order to define structural requirements, novel quinazolines, e.g. (IV), are synthesized and their anti‐melanogenesis activity is evaluated using melanoma B16 cells under the stimulant of α‐MSH.
ChemInform Abstract: An Efficient Synthesis of E‐2‐Amino‐4‐aryl‐8‐(arylmethylene)‐5,6,7,8‐tetrahydrobenzo [d]pyrimidines and Their Lower Analogues
Authors: Pal Rammohan , Mandal Tapas K. , Samanta Swati , Mallik Asok K.
Published: December 2010

via base‐mediated cyclocondensation of α,α′‐bis(arylmethylene)cycloalkanones with guanidinium chloride
ChemInform Abstract: A Simple Synthetic Approach to Unsymmetrically Substituted (γ‐Oxoalkyl)phosphine Oxides (III)
Authors: Tatarinov D. A. , Mironov V. F. , Baronova T. A. , Kostin A. A. , Buzykin B. I.
Published: December 2010

based on the reaction of P‐containing heterocycles (I) with Grignard reagents and subsequent hydrolysis
ChemInform Abstract: EPR and ENDOR Studies of Shallow Donors in SiC
Authors: Son N. T. , Isoya J. , Umeda T. , Ivanov I. G. , Henry A. , Ohshima T. , Janzen E.
Published: December 2010

Review: 85 refs.
ChemInform Abstract: Magnetic Exchange in Bi‐ and Polynuclear Complexes of Transition Metals with Hydrazones and Azomethines
Authors: Kogan V. A. , Lukov V. V. , Shcherbakov I. N.
Published: December 2010

Review: 198 refs.
ChemInform Abstract: In Water, on Water, and by Water: Mimicking Nature′s Aldolases with Organocatalysis and Water.
Authors: Mase Nobuyuki , Barbas Carlos F. III
Published: December 2010

Review: 105 refs.
ChemInform Abstract: Recent Progress in the Synthesis of Five‐Membered Heterocycles Boronic Acids and Esters
Authors: Primas Nicolas , Bouillon Alexandre , Rault Sylvain
Published: December 2010

Review: 87 refs.
ChemInform Abstract: Metal‐Catalyzed Asymmetric Conjugate Addition Reaction: Formation of Quaternary Stereocenters
Authors: Hawner Christine , Alexakis Alexandre
Published: December 2010

Review: 63 refs.
ChemInform Abstract: Triazole Nucleoside Derivatives Bearing Aryl Functionalities on the Nucleobases Show Antiviral and Anticancer Activity
Authors: Xia Y. , Qu F. , Peng L.
Published: December 2010

Review: 91 refs.
ChemInform Abstract: Phosphorus‐Containing Calixarenes
Authors: Cherenok Sergey , Kalchenko Vitaly
Published: December 2010

Review: 138 refs.
ChemInform Abstract: N‐Functionalized Organocuprates
Authors: Dieter R. Karl , Watson Rhett T.
Published: December 2010

Review: 260 refs.
ChemInform Abstract: Graphene‐Based Nanomaterials and Their Electrochemistry
Authors: Pumera Martin
Published: December 2010

Review: 38 refs.
ChemInform Abstract: From MFC to MXC: Chemical and Biological Cathodes and Their Potential for Microbial Bioelectrochemical Systems
Authors: Harnisch Falk , Schroeder Uwe
Published: December 2010

Review: 91 refs.
ChemInform Abstract: Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives.
Authors: Knop Katrin , Hoogenboom Richard , Fischer Dagmar , Schubert Ulrich S.
Published: December 2010

Review: 219 refs.
ChemInform Abstract: Formation Mechanism and Chemical Safety of Nonintentional Chemical Substances Present in Chlorinated Drinking Water and Wastewater
Authors: Onodera Sukeo
Published: December 2010

Review: 101 refs.
ChemInform Abstract: Recent Progress in Morphology Control of Supramolecular Fullerene Assemblies and Its Applications
Authors: Babu Sukumaran Santhosh , Moehwald Helmuth , Nakanishi Takashi
Published: December 2010

Review: 70 refs.
ChemInform Abstract: Family Business: Multiple Members of Major Phytohormone Classes Orchestrate Plant Stress Responses
Authors: Erb Matthias , Glauser Gaetan
Published: December 2010

Review: 120 refs.
Do All Hemolytic Anemias That Occur After Mitral Valve Repair Require Surgical Treatment?
Authors: Gungunes Askin , Akpinar Ibrahim , Dogan Mehmet , Baser Kazim , Yildirim Ismail Safa , Haznedaroglu Ibrahim C.
Published: December 2010

We report on a 29‐year‐old woman with severe hemolytic anemia following mitral valve annuloplasty. Although hemolysis due to mechanical prosthetic mitral valve is well recognized, hemolytic anemia associated with mitral valve repair is an uncommon condition. Reoperation may be considered if the patient has serious and persistent anemia. Although valve replacement is suggested to be a unique intervention, it may not be the solution every time because of mechanical effects. Various mechanisms of hemolysis related to mitral valve repair were suggested, but sufficient and precise data is not available. In this case, we tried to emphasize whether all hemolytic anemias that occur after mitral valve repair require surgical treatment. Copyright © 2010 Wiley Periodicals, Inc.
Frequency, Risk Factors, and Effect on Long‐Term Survival of Increased Troponin I Following Uncomplicated Elective Percutaneous Coronary Intervention
Authors: Loeb Henry S. , Liu Jayson C.
Published: December 2010

Background

The frequency, risk factors for, and effect on long‐term survival of increased troponin I (cTnI) following elective, uncomplicated percutaneous coronary intervention (PCI) remains uncertain.

Methods

We studied 907 patients undergoing elective PCI without recognized PCI complications and with at least 1 measurement of cTnI 12 or more h following the procedure. Patients with pre‐PCI cTnI above 0.1 ng/ml or with myocardial infarction within the previous 48 h were excluded.

Results

Maximal cTnI (TrMX) following PCI averaged 0.8 ng/ml, exceeded the upper normal of 0.1 ng/ml in 65.2% of patients and was 1.5 ng/ml or above in 13.7%. Of several demographic and procedural variables examined, the only significant predictor of TrMX was the number of stents deployed. (p < 0.0023 95% confidence interval [CI]: 0.10–0.46). Significant univariate predictors of survival (Kaplan‐Meier) were older age (p < 0.0001), diabetes (p = 0.02), peripheral vascular disease (p < 0.0001), obstructive lung disease (p < 0.0001), congestive failure (p < 0.0001), renal impairment (p < 0.0001), and TrMX of 3.62 ng/ml or above (p = 0.0451). Independent predictors (Cox) were older age (p < 0.0001), obstructive lung disease (p < 0.0001), congestive failure (p < 0.0001), and TrMX (p = 0.0272).

Conclusions

Elevation of cTnI occurs in most patients undergoing elective, uncomplicated PCI. Deployment of multiple stents is associated with higher values of cTnI. Long‐term survival is primarily influenced by age and pre‐PCI comorbidities, however patients with the highest values of cTnI after PCI are also at increased risk of reduced survival. Significant independent predictors of reduced survival were older age, obstructive pulmonary disease, congestive failure (p < 0.0001 for each), and maximal post‐PCI cTnI (p = 0.0272). Copyright © 2010 Wiley Periodicals, Inc.
Predictors and Long‐term Prognosis of Angiographic Slow/No‐Reflow Phenomenon During Emergency Percutaneous Coronary Intervention for ST‐Elevated Acute Myocardial Infarction
Authors: Dong‐bao Li , Qi Hua , Zhi Liu , Shan Wang , Wei‐ying Jin
Published: December 2010

Objective

Angiographic slow/no‐reflow during emergency percutaneous coronary intervention (PCI) in patients with ST‐elevated acute myocardial infarction (AMI) may result in unfavorable outcomes. The aim of our study was to investigate the clinical factors and angiographic findings that predict slow/no‐reflow phenomenon and the long‐term prognosis of AMI patients with angiographic slow/no‐reflow.

Methods

A total of 210 consecutive AMI patients, who underwent primary PCI within 12 hours of symptom onset were divided into a normal flow group (thrombolysis in myocardial infarction [TIMI] flow grade 3, n = 169) and a slow/no‐reflow group (≤TIMI flow grade 2, n = 41), based on cineangiograms performed during PCI.

Results

A total of 41 patients (19.5%) developed slow/no‐reflow phenomenon. Univariate analysis showed that delayed reperfusion, high thrombus burden on baseline angiography, and acute hyperglycemia all correlated with slow/no‐reflow (P < 0.05 for all). Multivariate analysis revealed that hyperglycemia on admission (≥10 mmol/L; odds ratio [OR]: 1.7, 95% confidence interval [CI]: 1.423–2.971, P = 0.012), reperfusion time (≥6 h; OR:1.4, 95% CI: 1.193–1.695, P = 0.040), and high thrombus burden (OR: 1.6, 95% CI: 1.026–2.825, P = 0.031) were significant and independent predictors of angiographic slow/no‐reflow. The 6‐month mortality and incidence of major adverse cardiac and cerebrovascular events (MACCE) were significantly higher in the slow/no‐reflow group than in the normal flow group. Angiographic slow/no‐reflow was independently predictive of MACCE (hazard ratio [HR]: 2.642, 95% CI: 1.304–5.932, P = 0.028).

Conclusion

Delayed reperfusion, high thrombus burden on baseline angiography, and blood glucose level on admission can be used to stratify AMI patients into a lower or higher risk for angiographic slow/no‐reflow during PCI. In addition, angiographic slow/no‐reflow predicts an adverse outcome in AMI patients. Copyright © 2010 Wiley Periodicals, Inc.
Two‐Dimensional Visualization of Cholesterol and Cholesteryl Esters Within Human Coronary Plaques by Near‐Infrared Fluorescence Angioscopy
Authors: Uchida Yasumi , Uchida Yasuto , Sugiyama Yukou , Tomaru Takanobu , Kawai Seiji , Kanamaru Ryohei , Shimoyama Ei
Published: December 2010

Background:

Cholesterol (C) and cholesteryl esters (CE) within coronary plaques are minimally visualized directly by any of the available imaging modalities in vivo. If they are rendered visible in vivo, the progression of coronary plaques and the effects of respective therapies on these plaques can be objectively evaluated.

Hypothesis:

The C and CE within human coronary plaques can be visualized by near‐infrared fluorescence angioscopy (NIRFA).

Methods:

By exciting at 710 ± 25 nm and emitting at 780 nm, near‐infrared fluorescence (NIRF) of lipid components was examined by microscopy in vitro. Lipid components in 49 plaques of 32 excised human coronary arteries were examined by NIRFA in vitro. Coronary plaques were examined by NIRFA in 25 patients with coronary artery disease.

Results:

C, CE, and calcium (Ca) individually did not exhibit NIRF but did in the presence of β‐carotene, which is known to coexist with lipids in the vascular wall. Other substances that are contained in atherosclerotic plaques did not.2 The excised human coronary plaques were classified as those with NIRF and those without. The former plaques were classified into homogenous, doughnut‐shaped, and spotty types. Histological examinations revealed that these image patterns were determined by the differences in the locations of C, CE, and Ca, and that those deposited within 700 μm in depth from the plaque surface were imaged by NIRFA. Homogenous, doughnut‐shaped, or spotty NIRFA images were also observed in patients.

Conclusions:

NIRFA is feasible for 2‐dimensional imaging of C and CE deposited in human coronary plaques. Copyright © 2010 Wiley Periodicals, Inc.

The authors have no funding, financial relationships, or conflicts of interest to disclose.
Cardio‐Oncology/Onco‐Cardiology
Authors: Hong Robert A. , Iimura Takeshi , Sumida Kenneth N. , Eager Robert M.
Published: December 2010

An understanding of onco‐cardiology or cardio‐oncology is critical for the effective care of cancer patients. Virtually all antineoplastic agents are associated with cardiotoxicity, which can be divided into 5 categories: direct cytotoxic effects of chemotherapy and associated cardiac systolic dysfunction, cardiac ischemia, arrhythmias, pericarditis, and chemotherapy‐induced repolarization abnormalities. Radiation therapy can also lead to coronary artery disease and fibrotic changes to the valves, pericardium, and myocardium. All patients being considered for chemotherapy, especially those who have prior cardiac history, should undergo detailed cardiovascular evaluation to optimize the treatment. Serial assessment of left ventricular systolic function and cardiac biomarkers might also be considered in selected patient populations. Cardiotoxic effects of chemotherapy might be decreased by the concurrent use of angiotensin‐converting enzyme inhibitors, angiotensin receptor blockers, or beta‐blockers. Antiplatelet or anticoagulation therapy might be considered in patients with a potential hypercoagulable state associated with chemotherapy or cancer. Open dialogue between both cardiologists and oncologists will be required for optimal patient care. Copyright © 2010 Wiley Periodicals, Inc.

The authors have no funding, financial relationships, or conflicts of interest to disclose.
Comparison of Actigraphic and Subjective Measures of Sleep in Implantable Cardioverter Defibrillator and Coronary Artery Disease Patients
Authors: Cross Natalie J. , McCrae Christina S. , Smith Karen M. , Conti Jamie B. , Sears Samuel F.
Published: December 2010

Background:

Cardiac patients frequently have insomnia symptoms that may pose risk for future cardiac events. Poor sleep relates to hyperarousal, anxiety and depression, and the incidence of hypertension and myocardial infarction.

Hypothesis:

The authors hypothesized that implantable cardioverter defibrillator (ICD) patients would have poorer sleep than coronary artery disease (CAD) patients related to hypervigilance for device functioning and shock discharge.

Methods:

Authors investigated sleep efficiency and sleep latency in a sample of 60 patients (n = 30 CAD and n = 30 ICD) without obstructive sleep apnea at the University of Florida & Shands Hospital. For 14 days, participants completed a sleep diary. Additionally, half of the total sample also used actigraphy to objectively measure their sleep. Measures of somatic hypervigilance and psychosocial distress were administered.

Results:

Using actigraphy, mean sleep efficiency was poorer (69.76%) in CAD patients compared with ICD patients (82.80%). This difference was highly significant, F1,27 = 16.840, P < 0.001. CAD patients also had shorter mean total sleep times per sleep diaries compared with ICD patients (336.19 minutes or 5.60 hours, 430.65 minutes or 7.18 hours, respectively), F1,27 = 15.908, P < 0.001.

Conclusions:

The finding that ICD patients slept more efficiently than CAD patients is surprising given that CAD patients had higher ejection fractions and no concerns about ICD shocks. This difference cannot be accounted for by differences in hypervigilance, depression, anxiety, or physical activity. Results suggest that CAD patients may have more sleep problems and may warrant increased research attention. Copyright © 2010 Wiley Periodicals, Inc.

Dr. Sears serves as a consultant to Medtronic, has or has had research grants from Medtronic and St. Jude Medical, and has received speaker honoraria from Medtronic, Boston Scientific, St. Jude Medical, and Biotronik. Dr. Conti serves as a consultant to Medtronic, has or has had research grants from Medtronic and St. Jude Medical, and has received speaker honoraria from Medtronic, Boston Scientific, and St. Jude Medical. The authors have no other funding, financial relationships, or conflicts of interest to disclose.
The Prevalence of Endothelial Dysfunction in Patients With and Without Coronary Artery Disease
Authors: Toggweiler Stefan , Schoenenberger Andreas , Urbanek Nadja , Erne Paul
Published: December 2010

Background:

Endothelial dysfunction (ED) is frequently present in patients presenting with acute or stable coronary artery disease (CAD), but it is also found in patients presenting with chest pain without angiographic coronary lesions.

Hypothesis:

We hypothesized that even in patients without CAD, the presence of cardiovascular (CV) risk factors will correlate with the presence of ED.

Methods:

Our study included a total of 341 consecutive patients referred for coronary angiography. We used pulse wave analysis with a finger plethysmograph (peripheral arterial tonometry) to determine endothelial function. Hyperemia ratio was calculated as the ratio of the postischemic hyperemia response relative to baseline measurement.

Results:

The hyperemia ratio was significantly higher in patients without CAD (2.02 ± 0.52) compared with patients with chronic CAD (1.81 ± 0.44, P = 0.001) or acute CAD (1.74 ± 0.49, P < 0.001). Prevalence of ED was 33%, 46%, and 58%, respectively. In multivariate analysis, the presence of CAD, diabetes, and cigarette smoking, and the total number of CV risk factors, were strong predictors of ED. In 67% of the patients without CAD but with ≥3 CV risk factors, ED was present.

Conclusions:

Prevalence of ED in patients with chest pain depends on the presence of CAD and CV risk factors. Patients without CAD but with ≥3 risk factors frequently presented with ED. Such patients may be at increased risk for future CV events and may profit from intensified therapy to control CV risk factors.

The authors have no funding, financial relationships, or conflicts of interest to disclose.

This study was supported by the Swiss Heart Foundation, Bern, Switzerland, and the Kamillo Eisner Foundation, Hergiswil, Switzerland. Stefan Toggweiler was supported by a grant from the Swiss National Foundation. None of the granting institutions had any influence on the study design, data collection, analysis, or interpretation.
Obesity Is an Independent Risk Factor for Heart Failure: Zona Franca Cohort Study
Authors: Baena‐Díez José M. , Byram Alice O. , Grau María , Gómez‐Fernández Claudia , Vidal‐Solsona Marc , Ledesma‐Ulloa Gabriela , González‐Casafont Isabel , Vasquez‐Lazo Javier , Subirana Isaac , Schroder Helmut
Published: December 2010

Background:

Heart failure (HF) is a major problem in developed countries. However, its relationship with obesity remains unclear, especially in low‐risk populations. The objective of the study was to analyze the relationship between obesity and HF in a low‐risk Mediterranean population.

Hypothesis:

Obesity is an independent predictor for HF.

Methods:

A prospective community‐based population cohort study with 10 years' follow‐up was conducted at 2 healthcare centers in the city of Barcelona, Spain. From a registered population of 35 275, the study included 932 randomly selected patients without HF, age 35–84 years. Obesity was defined as body mass index (BMI) ≥30 and HF according to European Society of Cardiology guidelines, confirmed by echocardiography. Cox proportional hazards regression was used to examine the association between obesity and heart failure.

Results:

The difference in HF incidence between obese subjects (4.7%) and nonobese subjects (1.6%) was 3.1% (95% confidence interval [CI]: 0.7–5.5). In the unadjusted model, incident HF was significantly associated with BMI: the hazard ratio [HR] was 1.09 for every 1 kg/m2 increase (95% CI: 1.05–1.14) and 3.01 for BMI ≥30 (95% CI: 1.34–6.77). After adjusting for age, sex, hypertension, ischemic heart disease, and diabetes mellitus, the results were similar: HR 1.06 (95% CI: 1.01–1.10) and HR 2.45 for BMI ≥30 (95% CI: 1.02–5.61). Overweight was not associated with HF in any of the models. The population‐attributable risk of HF due to obesity was 43.0% (95% CI: 13.9–74.9).

Conclusions:

High rate differences, HRs, and attributable risk indicate that obesity is an important risk factor for incident HF. Copyright © 2010 Wiley Periodicals, Inc.

This work was supported by grants from Instituto de Salud Carlos III‐FEDER0 (PI080439), and by a joint contract of the Instituto de Salud Carlos III and the Health Department of the Catalan Government.
Perceived Quality of Care and Lifestyle Counseling Among Patients With Heart Disease
Authors: Jackson Elizabeth A. , Krishnan Sangeetha , Meccone Nancy , Ockene Ira S. , Rubenfire Melvyn
Published: December 2010

Background:

To examine patients' perceived quality of care and reported receipt of information on diet and exercise related to cardiovascular disease prevention.

Methods:

Patients admitted with acute coronary syndromes or elective cardiac catheterization were eligible for enrollment. Baseline medical information was collected through medical‐record review. Patients completed surveys at the time of hospitalization that included items on perceived quality of care and whether they had received information from a healthcare provider on diet and exercise as related to their heart. Perceived quality of care was grouped into 3 categories: (1) poor to fair, (2) good, and (3) very good to excellent.

Results:

Among the 182 cardiac patients who completed the survey, those who reported poor to fair quality of care were more likely to report that they had received no advice regarding diet as compared with those who perceived their quality of care as good or very good to excellent (61%, 59%, and 26%, respectively, P < 0.0001). A similar pattern was observed for exercise (71%, 74%, and 36%, respectively, P < 0.0001).

Conclusions:

Patients with low perceived quality of care were less likely to have discussed diet and exercise habits with healthcare providers. Improving receipt of lifestyle counseling is warranted given the central role that diet and exercise play in secondary prevention. Copyright © 2010 Wiley Periodicals, Inc.

Dr. Jackson receives support from the National Heart, Lung, and Blood Institute of the National Institutes of Health (K23 HL073310‐01). The authors have no other funding, financial relationships, or conflicts of interest to disclose.
Endothelium as a Predictor of Adverse Outcomes
Authors: Della Rocca Domenico G. , Pepine Carl J.
Published: December 2010

The authors have no funding, financial relationships, or conflicts of interest to disclose.
Automatic External Defibrillator, Life Vest Defibrillator, or Both?
Authors: Richard Conti C.
Published: December 2010

magnified image

The standard of practice for out‐of‐hospital defibrillation is the implantable cardioverter‐defibrillator. However, much has been written and discussed about the use of automated external defibrillators. Not as much has been written about life vest wearable defibrillators. Copyright © 2010 Wiley Periodicals, Inc.
Reactions of Antimalarial Peroxides with Each of Leucomethylene Blue and Dihydroflavins: Flavin Reductase and the Cofactor Model Exemplified
Authors: Haynes Richard K. , Cheu Kwan‐Wing , Tang Maggie Mei‐Ki , Chen Min‐Jiao , Guo Zu‐Feng , Guo Zhi‐Hong , Coghi Paolo , Monti Diego
Published: December 2010

Flavin adenine dinucleotide (FAD) is reduced by NADPH–E. coli flavin reductase (Fre) to FADH2 in aqueous buffer at pH 7.4 under argon. Under the same conditions, FADH2 in turn cleanly reduces the antimalarial drug methylene blue (MB) to leucomethylene blue. The latter is rapidly re‐oxidized by artemisinins, thus supporting the proposal that MB exerts its antimalarial activity, and synergizes the antimalarial action of artemisinins, by interfering with redox cycling involving NADPH reduction of flavin cofactors in parasite flavin disulfide reductases. Direct treatment of the FADH2 generated from NADPH–Fre–FAD by artemisinins and antimalaria‐active tetraoxane and trioxolane structural analogues under physiological conditions at pH 7.4 results in rapid reduction of the artemisinins, and efficient conversion of the peroxide structural analogues into ketone products. Comparison of the relative rates of FADH2 oxidation indicate optimal activity for the trioxolane. Therefore, the rate of intraparastic redox perturbation will be greatest for the trioxolane, and this may be significant in relation to its enhanced in vitro antimalarial activities. 1H NMR spectroscopic studies using the BNAH–riboflavin (RF) model system indicate that the tetraoxane is capable of using both peroxide units in oxidizing the RFH2 generated in situ. Use of the NADPH–Fre–FAD catalytic system in the presence of artemisinin or tetraoxane confirms that the latter, in contrast to artemisinin, consumes two reducing equivalents of NADPH. None of the processes described herein requires the presence of ferrous iron. Ferric iron, given its propensity to oxidize reduced flavin cofactors, may play a role in enhancing oxidative stress within the malaria parasite, without requiring interaction with artemisinins or peroxide analogues. The NADPH–Fre–FAD system serves as a convenient mimic of flavin disulfide reductases that maintain redox homeostasis in the malaria parasite.
Activity of azacitidine in chronic myelomonocytic leukemia
Authors: Costa Rubens , Abdulhaq Haifaa , Haq Bushra , Shadduck Richard K. , Latsko Joan , Zenati Mazen , Atem Folefac D. , Rossetti James M. , Sahovic Entezam A. , Lister John
Published: December 2010

BACKGROUND:

Hypomethylating drugs are useful in the management of myelodysplastic syndrome (MDS). Two of these drugs, azacitidine and decitabine, have received FDA approval for the treatment of MDS and chronic myelomonocytic leukemia (CMML). However, phase 2 and 3 studies that assessed these agents in MDS included only a small number of patients with CMML. The objective of this study was to evaluate the efficacy and safety of azacitidine in the treatment of CMML.

METHODS:

The records of thirty‐eight patients diagnosed with CMML and treated with azacitidine at our institution were reviewed. Azacitidine was administered at 75 mg/m2/day for 7 days or 100 mg/m2/day for 5 days every 4 weeks. Patients who received at least 1 cycle of the drug were considered evaluable for response.

RESULTS:

Response was assessed by the modified International Working Group (IWG) criteria. The overall response rate was 39% (14 of 36); complete response (CR) rate was 11% (4 of 36); partial response (PR) rate was 3% (1 of 36); hematologic improvement (HI) was 25% (9 of 36). The median overall survival was 12 months. There was a statistically significant overall survival advantage in responders compared with nonresponders: 15.5 months versus 9 months, respectively (P = .04). Treatment was generally well tolerated. One of 2 patients had complete resolution of a skin rash that was due to monocytic infiltration.

CONCLUSIONS:

Azacitidine is active in the treatment of CMML. The therapy‐associated toxicity is acceptable. Our results support further investigation of azacitidine in CMML, particularly in combination with other agents. Cancer 2011;. © 2010 American Cancer Society.
Assessing gynecologic and breast cancer survivors' sexual health care needs
Authors: Hill Emily K. , Sandbo Stacey , Abramsohn Emily , Makelarski Jennifer , Wroblewski Kristen , Wenrich Emily R. , McCoy Stacy , Temkin Sarah M. , Yamada S. Diane , Lindau Stacy T.
Published: December 2010

BACKGROUND:

The objective of this study was to identify patterns of interest in receiving care for sexual concerns among women who were survivors of gynecologic and breast cancers.

METHODS:

Survey and medical records data were collected from June 2008 to March 2009 from 261 gynecologic and breast cancer patients. Logistic regression was used to estimate the effect of age and months since treatment on interest in receiving sexual healthcare.

RESULTS:

The mean participant age was 55 years (range, 21‐88 years). Only 7% of women had recently sought medical help for sexual issues, yet 41.6% were interested in receiving care. Greater than 30% responded that they would be likely to see a physician to address sexual matters, and 35% of all women were willing to be contacted if a formal program was offered. Compared with older women (aged >65 years), younger women (ages 18‐47 years) were significantly more likely to report interest in receiving care to address sexual issues (odds ratio [OR], 2.94; 95% confidence interval [CI], 1.14‐7.54) and to see a physician to address sexual matters (OR, 4.51; 95% CI, 1.51‐13.43), and they were more willing to be contacted for a formal program (adjusted OR [AOR], 5.00; 95% CI, 1.63‐15.28). Compared with women who were currently in treatment, women who last received treatment >12 months previously were significantly more interested in receiving care (AOR, 2.02; 95% CI, 1.02‐4.01) and were more willing to be contacted (AOR, 2.49; 95% CI, 1.18‐5.26).

CONCLUSIONS:

Greater than 40% of survivors expressed interest in receiving sexual healthcare, but few had ever sought such care. The current results indicated that there is an unmet need for attention to sexual concerns among women with gynecologic and breast cancers. Cancer 2011;. © 2010 American Cancer Society.