bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS PENGARUH MODAL DAN HARGA TERHADAP PENDAPATAN PETANI KELAPA SAWIT DI DESA KARTIKA BAKTI KECAMATAN SERUYAN HILIR TIMUR
Authors: * Suroto
Published: November 2023

Tujuan dari penelitian ini adalah untuk menganalisis dan mengetahui pengaruh modal dan harga terhadap pendapatan petani kelapa sawit di Desa Kartika Bakti Kecamatan Seruyan Hilir Timur. Metode yang digunakan dalam penelitian ini adalah metode kuantitatif dengan pendekatan survei dengan observasi, kuesioner dan wawancara. Variabel yang diukur adalah variabel modal dan variabel harga terhadap pendapatan petani kelapa sawit. Metode analisis data menggunakan analisis deskriptif, analisis regresi linier berganda dan uji t. Interpretasi hasil analisis menggunakan tingkat kepercayaan 95%. Hasil penelitian menunjukkan bahwa para petani kelapa sawit di Desa Kartika Bakti memiliki usia kisaran usia 40 tahunanan, hal ini menunjukkan bahwa para petani pada umumnya berada pada usia dengan produktifitas tinggi. Dari segi pendidikan, didominasi tamatan SD sekitar 75%, kemampuan pengambilan keputusan yang baik, didukung oleh kemudahan akses informasi dunia pertanian khususnya terkait kelapa sawit. Dari hasil skor kuesioner kita ketahui rerata untuk variabel modal, harga dan pendapatan mendapatkan angka diatas 4,0 sehingga dapat disimpulkan dalam kategori sangat baik. Hal tersebut menandakan bahwa para petani sudah memiliki kesiapan yang baik ketika memulai untuk masuk pada kegiatan budidaya tanaman kelapa sawit, para petani meyaqini akan prospek yang bagus untuk bisnis kelapa sawit kedepannya. Hasil uji regresi linier berganda diketahui bahwa nilai signifikansi variabel modal 0,002 dan nilai signifikansi variable harga 0,000, sehingga variabel modal dan variable harga dinyatakan berpengaruh secara signifikan terhadap pendapatan petani kelapa sawit di Desa Kartika Bakti. Kemudian berdasarkan hasil regresi tersebut disimpulkan bahwa Ho diterima dan Ha ditolak, artinya variabel modal berpengaruh sifnifikan terhadap pendapatan petani kelapa sawit di Desa Kartika Bakti Kecamatan Seruyan Hilir Timur.
ANALISIS LEMBAGA DAN SALURAN PEMASARAN KOPRA DI DESA PEMATANG KAMBAT, KECAMATAN SERUYAN HILIR TIMUR, KABUPATEN SERUYAN
Authors: Yanis Muhammad Nazarul , * Ariadi
Published: November 2023

Penelitian ini bertujuan untuk mengetahui fungsi dari lembaga pemasaran dan pola saluran pemasaran usaha kopra di Desa Pematang Kambat. Dilaksanakan pada bulan Agustus 2022, berlokasi di Desa Pematang Kambat, Kecamatan Seruyan Hilir Timur, Kabupaten Seruyan, Provinsi Kalimantan Tengah. Metode yang digunakan yaitu metode survei eksplorasi menggunakan teknik wawancara dengan kuisioner sebanyak 30 pertanyaan kepada 6 orang responden yang terletak di beberapa lokasi yaitu di Jalan Kelapa, Jalan Pematang Kambat, Pematang Manggis dan Pematang Kelapa. Penelitian ini dilakukan selama 14 hari, yang meliputi penyiapan alat dan bahan, survei dan wawancara, pengisian kuisioner, pengambilan data serta dokumentasi. Data hasil survei kemudian dianalisis secara deskriptif. Hasil penelitian menunjukan pola saluran pemasaran kopra yaitu dari Produsen – Pedagang Besar – Pengecer – Konsumen. Fungsi dari masing-masing lembaga pemasaran diketahui bahwa produsen melakukan semua fungsi pemasaran kecuali untuk fungsi pembelian. Pedagang besar juga melakukan semua fungsi pemasaran kecuali untuk fungsi pengangkutan. Sedangkan pengecer hanya melakukan fungsi pemasaran yaitu pembelian, penjualan, pengangkutan, pembiayaan dan informasi pasar.
The Efficacy of Erector Spinae Plane Block for Thoracoscopic Surgery: A Meta-Analysis of Randomized Controlled Trials
Authors: Liu Ling , Zhao Yuhua , Yongpeng He  , Peng WenLi , He Huan , Liang Ling
Published: November 2023

Background: The efficacy of erector spinae plane block for thoracoscopic surgery remains controversial. We conducted a systematic review and meta-analysis to explore the impact of erector spinae plane block on thoracoscopic surgery. Methods: We searched the PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases through February 2022 for randomized controlled trials (RCTs), assessing the effect of erector spinae plane block on thoracoscopic surgery. This meta-analysis was performed using the random-effect model. Results: Seven RCTs, involving 439 patients, are included in the meta-analysis. Overall, compared with the control group for thoracoscopic surgery, erector spinae plane block (ESPB) results in significantly reduced pain scores at 1 h (standard mean difference (SMD) = –4.26; 95% confidence interval (CI) = –7.63 to –0.88; p = 0.01), 4 h (SMD = –4.08; 95% CI = –4.56 to –3.60; p < 0.00001), 8 h (SMD = –4.13; 95% CI = –4.62 to –3.65; p < 0.00001), and postoperative anesthesia consumption (SMD = –3.04; 95% CI = –4.58 to –1.50; p = 0.0001) and can decrease the incidence of nausea and vomiting (odd ratio (OR) = 0.18; 95% CI = 0.08 to 0.39; p < 0.001). Conclusions: ESPB can substantially enhance pain relief for thoracoscopic surgery.
Meta-Analysis of the Efficacy of Levosimendan in the Treatment of Severe Sepsis Complicated with Septic Cardiomyopathy
Authors: Guan Qiongchan , Zhang Chuang , Li Binbin , Huang Daochao , Li Aiming , Qin Jie , Zhang Xianhuan
Published: November 2023

Introduction: Sepsis is a medical condition characterized by acute organ dysfunction and uncontrolled inflammation. Organ dysfunction in sepsis is the primary cause of mortality in patients with myocardial dysfunction. Levosimendan is a vasodilating and inotropic agent used in patients with acute heart failure and has resulted in decreased morbidity and mortality in these patients. Our main objective is to examine levosimendan's efficacy in treating severe sepsis complicated with septic cardiomyopathy. Methods: We systematically searched five databases, PubMed, Web of Science, Embase, Cochrane Library and BioMed Central, for articles and publications from their inception to 2023. Our study adopted the PICOS approach in identifying suitable publications during the systematic search. Inclusion criteria included randomized, controlled trials utilizing levosimendan in adult patients diagnosed with septic shock or severe sepsis. We excluded non-English publications and non-randomized controlled trials. The Newcastle-Ottawa scale (NOS) scale was used to assess the methodological quality, while the risk of bias was assessed through the Cochrane Risk of bias tool. All statistical analyses were performed using RevMan version 5.4. Results: Eight studies met the eligibility criteria and were included in the analysis. There was a statistically significant positive effect on cardiac input in patients treated with levosimendan compared to those treated with dobutamine (p < 0.001). Similarly, there were positive effects on left ventricular ejection fraction (LVEF) (p < 0.001) and left ventricular stroke work index (LVSWI) (p < 0.001). We observed a significant reduction in mortality (p < 0.01) and serum levels of lactic acid (p < 0.01). Discussion: Levosimendan is a calcium sensitizer associated with an influx of calcium ions and activation of ATP-dependent potassium channels that increases myocardial contractility contractions, enhances vasodilation and improves oxygen supply to the cells and tissues. Conclusion: Levosimendan is highly efficacious and safe in the management of sepsis and sepsis-induced cardiomyopathy.
PRECEDENTE VINCULANTE COMO FONTE DO DIREITO
Authors: Ferreira da Silva Marcio Evangelista , Martins Sales Cleber
Published: November 2023

The present work addresses the figure of judicial precedent, initially investigating whether it is a primary source of law. Its general objective is to identify whether, in fact, decisions taken in a given case, according to the current procedural system, can give rise to rights and obligations in the national order, and, specifically, to address the issue of the need to identify the effective reason for deciding (ratio ) of each judicial precedent itself, seeking a basic methodology that can prevent the practice of mere invocation of precedents and menus as if it were a legitimate precedent interpretation. The approach is justified based on the procedural shift established with the CPC of 2015, through legal and doctrinal research on the subject, to conclude by the binding and normative force of the precedents provided for in Brazilian legislation.
O CASO DOS EMPREGADOS DA FÁBRICA DE FOGOS DE SANTO ANTÔNIO DE JESUS
Authors: Galdino de Araújo Lucena Lucas Rafael , Leite de Carvalho Augusto César
Published: November 2023

El trabajo analiza el Caso de los Empleados de la Fábrica de Fuegos de Santo Antônio de Jesus y sus Familiares vs Brasil. Los objetivos de este estudio son: a) hacer una contextualización histórica sobre el evento; b) señalar el desarrollo del caso en la justicia interna brasileña; c) narrar el proceso procesal ante la Comisión Interamericana de Derechos Humanos, hasta su sometimiento ante la Corte Interamericana de Derechos Humanos; d) analizar su sentencia en el citado tribunal internacional, con especial énfasis en los alegatos preliminares, incluyendo la alegada falta de competencia en la materia de la Corte Interamericana para juzgar violaciones de derechos sociales, económicos y culturales. Al final, se concluye que la tragedia muestra, por un lado, la marginación duradera y aún presente de los negros en el país; por otro lado, demuestra la importancia de contar con un sistema supranacional para la defensa de los derechos humanos, incluyendo la protección de los derechos sociales.
A ADAPTAÇÃO RAZOÁVEL APLICADA POR MEIO DO TELETRABALHO AOS DEFICIENTES E SEUS CUIDADORES
Authors: Herculano Letícia , Belmonte Alexandre Agra
Published: November 2023

The scope of this work is to analyze the difficulties of people with disabilities, as well as their caregivers, to stay at work. In this sense, reasonable adaptation was proposed by the Convention on the Rights of Persons with Disabilities - CRPD, which was ratified by Brazil. There are several forms of reasonable adaptation, however, this article highlights how telework can become one of the most helpful alternatives. Thus, considering that each individual has its own needs, the caregiver of the person with disability must indicate which reasonable adaptation would be best for their case, which cannot cause a disproportionate burden to the employer.
A INCLUSÃO DE PESSOAS COM DEFICIÊNCIA NAS FORÇAS ARMADAS
Authors: Ravazi Madera Clóvis Roberto , Leite de Carvalho Augusto César
Published: November 2023

Este artigo trata da inclusão de pessoas com deficiência (PCD) como possível força de trabalho nas Forças Armadas, tendo como norteadores a Constituição Federal de 1988, o Estatuto da Pessoa com Deficiência (Lei n. 13.146/2015), a Convenção das Nações Unidas sobre os direitos das pessoas com deficiência, dentre outras leis. Tratou-se também da equivalência a Emenda Constitucional e das possíveis adaptações do ambiente de trabalho para essas pessoas. Foram abordados ainda conceitos e considerações a respeito de discriminação direta e indireta das PCD, além de levantamentos a respeito do serviço militar, de acordo com a Lei nº 4.375, de 17 de agosto de 1964, a Lei do Serviço Militar.
LEI GERAL DE PROTEÇÃO DE DADOS, AS RELAÇÕES DE TRABALHO À LUZ DO DESENVOLVIMENTO SUSTENTÁVEL
Authors: Ferraz Ottoni Mara Ruth , Farias Paulo José Leite
Published: November 2023

O presente artigo aborda a proteção dos dados pessoais, como direito da personalidade, diante da Lei Geral de Proteção de Dados, a Lei 13.709/2018. Apresenta-se uma visão da globalização e da informatização dos dados pessoais e seu compartilhamento massivo. Aborda-se uma comparação com a lei geral de proteção de dados europeia(GDPR) e a base principiológica e fundamentos da Lei brasileira de proteção de dados. Analisa-se os destinatários da norma em comento, seu papel e responsabilidades. Faz-se uma contextualização da legislação especial no direito trabalho e os cuidados com os dados pessoais e sensíveis do trabalhador e implicações ao empregador e a sua visão à luz dos indicadores brasileiros para os objetivos de desenvolvimento sustentável.
A COMPLEXIDADE DA INCERTEZA NA EDUCAÇÃO
Authors: Pettenon Evandir Antonio , ´Ávila Assunção Any
Published: November 2023

This article is the result of studies and research conducted in the discipline of Applied Methodology of Legal Research, more specifically the approach of the Morin Complexity Paradigm. As it is already applied to science, methodology, and also to education, which for Morin has always been his field of concern and research, UNESCO even asked him to systematize a set of reflections that would serve as a starting point to rethink the education of the new millennium, which is his work: The Seven Knowledges necessary for the education of the future. It will also be grafted some Brazilian thinkers like Pedro Demo with his ambivalences of knowledge and life, certainty and uncertainty, which resembles Morin in this approach. Paulo Freire more than anyone reminded us that no one teaches anyone, no one learns alone, we learn together. Also, as an example of how to do this in practice, José Pacheco with his Ponte School. Finally, remembered by Alain Touraine who needs a school of the subject to continue the search and struggle for recognition that encourages us Axel Honneth.
The Overview of Knowledge Level of Seven Semester Students of Anesthesiology Nursing Study Program on Evidence Based Practice 2 Course At Harapan Bangsa University Purwokerto
Authors: Area Dhiatamaa Sketsa , Sukmaningtyas Wilis , Burhan Asmat
Published: November 2023

Background Evidence Based Practice (EBP) is scientific evidence with clinical expertise, pathophysiological knowledge, knowledge of psychosocial issues, and patient preference decision making. Based on data from WHO and the European Commission, health and social services must be supported by the best research evidence. Evidence Based Practice (EBP) plays an integral role in health care and has been recognized internationally as an ideal problem-solving approach. The ability of students to engage in understanding Evidence Based Practice is also still low, faculty in Iran who explain that knowledge of students involved regarding Evidence Based Practice is still low (47.1%). Meanwhile, undergraduate students' understanding of the main evidence-based practices in terms of assessment, discovery, and research applications is still low, namely (39%). Objective: To determine the level of knowledge of students of the Fellowship Study Program in the 7th semester of the applied undergraduate program regarding the Evidence Based Practice 2 course at Harapan Bangsa University. Methods: This study used a quantitative method with a cross sectional approach. The sample in this study used a non-probability sampling technique with a total sampling of 151 respondents. Results : The most dominant age of respondents with a good level of knowledge in the Evidence Based Practice 2 course in this study was 21-22 years old, with a percentage of 112 respondents (94.1%), gender with a good level of knowledge in the Evidence Based course The most dominant Practice 2 in this study was female, as many as 75 respondents with a percentage of (93.8%), the level of knowledge of respondents in the Evidence Based Practice 2 course in this study. The most dominant were respondents with a good level of knowledge, as many as 138 respondents with a percentage (91.4%).
The Impact of Progressive Muscle Therapy on Anxiety Levels Among Pre-Anaesthesia Patients at RSI Banjarnegara
Authors: Lolandia Septin Cita , Lintang Suryani Roro , Utami Tin , Suandika Made
Published: November 2023

Purpose: Determine the effect of progressive muscle therapy on the anxiety level of pre-anesthesia patients at RSI Banjarnegara. Methods: This type of research is pre experiment pre test and post test with one group design. The sample technique in this study used purposive sampling of 37 pre-anesthesia patients. Data were taken using measurements of anxiety before and after progressive muscle therapy. This research instrument used questionnaires and SOP for progressive muscle therapy. Result: The anxiety level of respondents before being given progressive muscle therapy was the majority of 26 respondents (70.3%) experienced moderate anxiety. The anxiety level of respondents after being given progressive muscle therapy was the majority of 20 respondents (54.1%) experienced mild anxiety. The results of data analysis in this study with paired t test showed a value of (p) 0.000 ˂ 0.05. Conclusion: This shows that there is a significant influence on the provision of progressive muscle therapy at RSI Banjarnegara. Based on the results of the study, it is expected that the Banjarnegara RSI service will use progressive muscle therapy to reduce pre-anesthesia anxiety levels
Miljøvurdering som accept- og legalitetsplanlægning
Authors: Elling Bo , Nielsen Helle Nedergaard
Published: November 2023

Artiklen analyserer de senere års udvikling i borgerdeltagelsen indenfor miljøvurderinger og peger på en række uheldige og utilsigtede virkninger. Det vises, hvorledes redskaberne i højere grad anvendes til en slags acceptplanlægning end til egentlig miljøbeskyttelse og at den legitimitet, som borgerinddragelse var tiltænkt at tilføre miljøplanlægningen, snarere er blevet erstattet af en legalitetstænkning, som fritager bygherre og myndigheder fra at medtænke et egentligt miljøhensyn i deres planlægning. Således tilskrives den analyserede uhensigtsmæssige håndtering af borger- deltagelse ikke blot de faktiske vanskeligheder i praktiseringen af inddragelse og miljøproble- mernes uomtvistelige kompleksitet, men i høj grad et hensyn til økonomisk effektivitet og uvillighed blandt investorer – offentlige som private – til at anskue miljøomkostninger som et langsigtet forhold. Artiklen munder ud i en række anbefalinger der potentielt kan styrke borgerinddragelse i miljøvurderingssager gen- nem selvstændige borgerinitiativer eller insti- tutioner, der er uafhængige af myndigheder og bygherrer.
Écrire dans la bourrasque. À propos d’Hélène Cixous
Authors: Bismuth Léa
Published: November 2023

Hélène Cixous conçoit la littérature comme une embarcation périlleuse, ouvrant un espace par lequel elle exige, dynamiquement, de rompre les amarres et de passer quoi qu’il en coûte. En nous appuyant sur des récits récents de l’écrivaine (L’Amour du loup et autres remords, 2003 et Défions l’augure, 2018), il s’agira de déceler les principes d’une injonction à écrire. Pour cela, le corpus intertextuel choisi — via Michel de Certeau, Roland Barthes et Jacques Derrida notamment — tentera de déceler en quoi l’écriture relève d’une tempête évènementielle (tout autant que d’un élan mystique, d’un départ, d’un risque à prendre). En conférant à l’acte d’écrire toutes les caractéristiques d’une véritable effraction, on en élargira la puissance existentielle, en la mettant en perspective avec des philosophes contemporains de l’acte de création, tels que Patrice Loraux et Paul Audi.
Circulating Platelets Modulate Oligodendrocyte Progenitor Cell Differentiation During Remyelination
Authors: Philp Amber R. , Reyes Carolina R. , Mansilla Josselyne , Sharma Amar , Zhao Chao , Valenzuela-Krugmann Carlos , Rawji Khalil S. , Gonzalez Martinez Ginez A. , Dimas Penelope , Hinrichsen Bryan , Ulloa-Leal César , Waller Amie K. , Bessa de Sousa Diana M. , Castro Maite A. , Aigner Ludwig , Ehrenfeld Pamela , Silva Maria Elena , Kazanis Ilias , Ghevaert Cedric , Franklin Robin J.M. , Rivera Francisco J.
Published: November 2023

Revealing unknown cues that regulate oligodendrocyte progenitor cell (OPC) function and remyelination is important to optimise the development regenerative therapies for multiple sclerosis (MS). Platelets are present in chronic non-remyelinated lesions of MS and an increase in circulating platelets has been described in experimental autoimmune encephalomyelitis (EAE) mice, an animal model for MS. However, the contribution of platelets to remyelination remains unexplored. Here we show platelet aggregation in proximity to OPCs in areas of experimental demyelination. Partial depletion of circulating platelets impaired OPC differentiation and remyelination, without altering blood-brain barrier stability and neuroinflammation. Transient exposure to platelets enhanced OPC differentiation
in vitro
, whereas sustained exposure suppressed this effect. In a mouse model of thrombocytosis (

CALR
HET

), there was a sustained increase in platelet aggregation together with a reduction of newly-generated oligodendrocytes following toxin-induced demyelination. These findings reveal a complex bimodal contribution of platelet to remyelination and provide insights into remyelination failure in MS.
Progress in overactive bladder: novel avenues from psychology to clinical opinions
Authors: Jin Zhaofeng , Zhang Qiumin , Yu Yanlan , Zhang Ruilin , Ding Guoqing , Li Tian , Song Yuping
Published: November 2023

Rationale

Overactive bladder (OAB) is a common, distressing condition that worsens with age and impacts quality of life significantly. As a results of its clinical symptoms, patients suffer from serious physical and mental health issues, have a poor quality of life, and participate in a serious economic burden. The key social-psychological factors include living habits, eating habits, and personality characteristics on this disease, even though the pathogenesis of OAB is complex. However, there is few cognitions and research on OAB in the field of psychology.

Methods/Search Strategy

Between 2000 and 2022, two electronic databases were systematically searched in accordance with Cochrane library guidelines (PubMed/Medline, Web of Science). An analysis of the remaining articles with relevant information was conducted using a data extraction sheet. An itemized flow diagram was adopted and used to report systematic reviews and meta-analysis. A systematic review of studies published from 2000 to 2022 in English language were conducted and included in the review.

The intended audience

Urological surgeon and psychologists majoring in urinary diseases.

Implication

As a result of this information, we are able to develop a better understanding of the role of psychological factors in the development of OAB and suggest potential therapeutic directions for OAB patients. This may benefit the recovery of OAB patients.
Systematic Study of Computer Virus using Virus Definition and Scanning Techniques
Authors: Zayyad Musa Ahmed
Published: November 2023

Background: Computer virus pose increased risk to computer data integrity, they cause loss of important information and data and cost a huge enormous amount in wasted effort in restoration or duplication of lost and damaged data. Everyday new viruses are discovered, and as the problem increases, there is the need to employ modern tools to identify them and to eliminate them from the devices.

Objective: This study will examine computer viruses and their impact to computer system.

Methodology: The study adopted the mixed research method of quantitative and qualitative techniques. In this study data was collected using both interview and observation methods, as well as comprehensive search of the literature review of various scholars from relevant databases such as Research Gate, Google Scholar, and dimension.

Results: This study identified how devices are vulnerable to computer virus attack and how modern technologies can actually increase the propagation of computer viruses. It also describes the technologies that are available to identify and eliminate the computer viruses, hence, propound probable good uses of virus technology.
Studies on Physico-chemical Characteristic of Some Varieties/ Genotypes in Various Brassica Species
Authors: Kumar Raj , Maurya C. L. , Kumar Nand , Kumar Dipak , Ashish Ram , Kumar Ajay , Kumar Sanjay , Singh Shakti
Published: November 2023

The present study was conducted in the laboratories of the Department of Agricultural Biochemistry to evaluate thirty nine varieties/genotypes of Brassica Species for physical and chemical characteristics such as moisture content, Test weight, Oil content, Protein content in meal and Methionine content in meal. The samples was collected from University farm as well after grading of the sample the quality analysis in the laboratory was conducted as per standard procedures. Moisture content in different varieties/genotypes of yellow sarson varied from 5.60 to 3.25% while toria entries varied from 5.05 to 3.48%. In case of rai the range of variation was 5.67 to 3.56%. Test weight in different varieties/genotypes of yellow sarson varied from 5.70 to 3.40 g/1000 seed, while toria entries varied from 5.10 to 3.50 g/1000 seed. In case of rai the range of variation was 4.28 to 3.23 g/1000 seed. Oil content in different varieties/genotypes of yellow sarson varied from 42.55 to 36.20%, while toria entries varied from 42.05 to 34.40%. Whereas rai entries recorded variability of 39.05 to 32.40%. Protein content in different varieties/genotypes of yellow sarson varied from 40.55 to 27.93%, while toria entries varied from 30.03 to 28.33%. In case of rai the range of variation was 31.10 to 28.95%. Methionine content in different varieties/genotypes of yellow sarson varied from 1.98 to 0.99 g/100g, while toria entries varied from 2.12 to 1.14 g/100g. In case of rai the range of variation was 1.84 to 1.22 g/100g.
Evaluation of Water Quality and the Potential Ecological and Health Risk in the Cajititlán Lagoon
Authors: Ramírez-Sánchez Hermes Ulises , Fajardo-Montiel Aida Lucia , Cabrera-Chavarría José de Jesús , Carrasco-García Julieta
Published: November 2023

Water security threatens the world's population, so the evaluation of the water quality of water bodies is one of the critical issues and is a current challenge to ensure the sustainability of ecosystems and human population.

Objective: The aim is to estimate the physicochemical parameters and heavy metals of the water of the Cajititlán Lagoon during the period 2009-2023, to evaluate its water quality, ecological and health risks. The results will supply valuable information on water quality management and human health protection.

Study Design: Ecological study, using water quality, pollution, ecological and health risk indices.

Place and Duration of the Study: Cajititlán Lagoon during the period 2009-2023.

Methodology: The water quality data of Lagoon Cajititlán were obtained through the State Water Commission of the government of the State of Jalisco. The analyses were performed monthly from 2009 to 2023. CWQI, WQI, NP, HPI, HEI, DC, PERI, HQ, HI, THI, CR and TCR indices were then calculated to find water quality and ecological and health risks.

Results: The distribution of parameter concentration showed a drastic spatial variation, but not temporal. The TDS, Turbidity, pH, F, Al, As, Cr, Cu, Mn, Ni, Pb and Zn showed percentages above the CCME regulations, however most are within the NOM-001-SEMARNAT-2021. The heavy metals Al, Cr, Ni, Pb, Zn and As are those that present the % concentration of more than 100% with respect to the international standard. The remaining 14 parameters are within both national and international standards. Pearson's correlation analysis showed that most heavy metals have positive correlations with each other, except for Cr, Pb and Cu. Water quality according to WQI of 112 was categorized as poor-quality, while for CWQI all uses except livestock, water quality is poor (20-35). According to the NP index (0.19 to 670), heavy metal concentrations showed high contamination levels. The HPI index (89) showed moderate to elevated levels of heavy metal contamination. The HEI index showed levels <10, showing low pollution. The DC presented a value of 4, classified as a high degree of contamination. The PERI index showed that the ecological risk from heavy metals is high. Non-carcinogenic risk indices show that lagoon water is not suitable for drinking, and poses a high health risk via ingestion, while dermal contact poses no health risk to residential and recreational recipients. The results say that As would not pose a carcinogenic risk to residents and recreational receptors in different surface waters, while Cr may pose a slight carcinogenic risk to recreational receptors.

Conclusions:  According to the indices of water quality, ecological risk and health, the water quality of the Cajititlán Lagoon is poor, with a high degree of contamination and stands for ecological and health risks (non-carcinogenic).
Understanding the spirit of a norm: Challenges for norm‐learning agents
Authors: Arnold Thomas , Scheutz Matthias
Published: November 2023

Social and moral norms are a fabric for holding human societies together and helping them to function. As such they will also become a means of evaluating the performance of future human–machine systems. While machine ethics has offered various approaches to endowing machines with normative competence, from the more logic‐based to the more data‐based, none of the proposals so far have considered the challenge of capturing the “spirit of a norm,” which often eludes rigid interpretation and complicates doing the right thing. We present some paradigmatic scenarios across contexts to illustrate why the spirit of a norm can be critical to make explicit and why it exposes the inadequacies of mere data‐driven “value alignment” techniques such as reinforcement learning RL for interactive, real‐time human–robot interaction. Instead, we argue that norm learning, in particular, learning to capture the spirit of a norm, requires combining common‐sense inference‐based and data‐driven approaches.
The Portal Galleries: Researching Portals in Fiction from the 19th Century to the Present
Authors: Lesmes Lara , Hellberg Fredrik
Published: November 2023

The notion of portals to alternative multispaces where normalcy is subverted into magical situations has been a feature of fiction for centuries. Architects and educators Lara Lesmes and Fredrik Hellberg have catalogued some of these fictive realms and mechanisms, and developed their own augmented‐reality portal to show the results of their research.
Architecture in Postreality: Emerging Approaches to Space in Hybrid Realities
Authors: Damiani Jesse
Published: November 2023

For decades, the realm within which architects work was limited to its realworld materiality and ideas of industrialised modernism. This straitjacketed prescription has recently been challenged by the advent of the virtual, through technologies that have blown the profession wide open to new and highly dexterous spatial opportunities that question the old adages that sustained many generations of architects. Curator and writer Jesse Damiani reveals some of the ramifications for design.
Ways of Worlding: Building Alternative Futures in Multispace
Authors: Bucknell Alice
Published: November 2023

The integration of the real and the digital – particularly gaming engines – offers architects and designers the opportunity to develop narrative environments that can be predicated on speculative fiction. Such spaces, landscapes and buildings explore magical panoramas created not just by human ingenuity, but also by machine and nonhuman intelligence. Artist and writer Alice Bucknell takes us into some of these possible worlds.
The Anti‐Metaverse: Multispace and the Intersections of Reality
Authors: Mantegna Micaela , Rinesi Marcelo
Published: November 2023

Virtual spaces offer the incredible mix of opportunities and risks that are only available when designing a new universe (almost) from scratch. Arguing that these spaces are just as real as the ‘real world’, Micaela Mantegna and Marcelo Rinesi point out that architects are obligated to share their intellectual and visualising skills beyond the discipline to give more of humanity the possibility of operating in their own multispatial environments, and in so doing taking the legislation of space away from the neoliberal few.
High Interfacial Shear Strength and High Tensile Strength in Heterocyclic Aramid Fibers with Improved Interchain Interaction
Authors: Luo Jiajun , Wen Yeye , Li Tao , Jia Xiangzheng , Lei Xudong , Zhang Ziyi , Xiao Zhihua , Wu Xianqian , Gao Zhenfei , Gao Enlai , Jiao Kun , Zhang Jin
Published: November 2023

As a typical kind of high‐performance fibers, heterocyclic aramid fibers are widely used to reinforce resins to prepare advanced lightweight composites with high mechanical performances. However, their poor interfacial shear strength limits the combination with resins and leads to undesirable interfacial strength of composites. Thus, heterocyclic aramid fibers with high interfacial shear strength and high tensile strength are highly desired. Herein, heterocyclic aramid fibers with a high interfacial shear strength of 40.04 ± 2.41 MPa and a high tensile strength of 5.08 ± 0.24 GPa are reported, in which the nitrile‐modified poly‐(benzimidazole‐terephthalamide) polymer chains are crosslinked by azide‐functionalized graphene oxide nanosheets. The improved interchain interaction can conquer the splitting of nanofibrils and strengthen the skin‐core layer of heterocyclic aramid fibers, while the graphene oxide can induce an ordered arrangement of polymer chains to improve the crystallinity and orientation degree of fibers. These two effects account for the high interfacial shear strength and high tensile strength of heterocyclic aramid fibers. These findings have provided a strategy to efficiently enhance the interfacial shear strength as well as the tensile strength of high‐performance fibers.
The Elements Selection of High Entropy Alloy Guided by Thermodynamics and the Enhanced Electrocatalytic Mechanism for Oxygen Reduction Reaction
Authors: Wang Kun , Chen Rui , Yang Hao , Chen Yuhui , Jia Hao , He Yu , Song Shuqin , Wang Yi
Published: November 2023

Owing to their exceptional properties, high‐entropy alloys (HEAs) have received considerable attention in the field of electrocatalysis. However, few studies focus on the origin of their outstanding performance. Here, carbon‐supported PtFeCoNiMn (with an atomic ratio of 21:20:20:20:19) HEA nanoparticles via shock‐heating and shock‐cooling strategy are rationally designed and successfully prepared. The above five metal elements are rationally selected from the perspective of thermodynamics and geometric effects. Subsequently, the alloying process of the PtFeCoNiMn HEA is investigated via operando X‐ray diffraction characterizations. The electronic structures of each metal atom on the PtFeCoNiMn HEA and monometallic nanoparticles surface are revealed by density function theory calculations for illustrating the performance enhancement mechanism. It is found that Pt atoms on the PtFeCoNiMn HEA surface exhibit a wider range of d‐band center distribution range than the corresponding monometallic nanoparticles, which contributes to the enhanced selective adsorption of O2 reactants/intermediates. Importantly, some Fe, Co, Ni, and Mn atoms on the HEA surface manifest less positive d‐band center values than the corresponding monometallic nanoparticles, with similar d‐band center positions to some Pt atoms. This indicates that the inactive atoms in monometallic nanoparticles can be transformed into ORR active sites in the HEA matrix owing to the electronic interaction between adjacent atoms.
Laser Thermal Shock Enabling Ultrafast Spin Regulation of MnO2 for Robust Pseudocapacitive Energy Storage
Authors: Wan Yi , Cao Tong , Li Yanan , Wang Bin , Wang Wanli , Xu Yujie , Yang Hao , Zhang Dongqing , Zhang Daliang , Li Qiang , Yu Chang , Hu Han , Wu Mingbo
Published: November 2023

The pseudocapacitive performance of MnO2 is intrinsically determined by its electronic structure, especially the spin state. However, the correlation between the electrochemical behavior and the spin state of electrode materials remains ill‐defined, and efficient spin regulation strategies for MnO2 are thus lacking. Herein, the study reports laser thermal shock of electrochemically deposited MnO2 for efficient spin regulation. The combined use of theoretical calculation and experimental investigation indicates that the thermal shock induces oxygen vacancy in MnO2 to reduce spin polarization and delocalize electron distribution. As a result, the electrical conductivity largely increases and the Na+ adsorption is reasonably optimized. By lasering an integrated electrode for only 83 s, a 54% increase of the specific capacitance is observed. For the first time, the pseudocapacitive capability of MnO2 is revealed by in situ electron paramagnetic resonance where the enhanced redox pair is correlated with evolution of Mn2+ during charge/discharge. Moreover, the commercial‐level mass‐loaded electrode also offers a decent performance enhancement after laser treatment, indicating the great prospect of this technology for real applications. This work innovatively correlates the pseudocapacitive performance of MnO2 with its spin state and offers a new avenue to optimize the electrochemical capability through spin regulation.
Stereoselective Synthesis of Fluoroalkanes via FLP Mediated Monoselective C─F Activation of Geminal Difluoroalkanes
Authors: Csókás Dániel , Mondal Bivas , Đokić Miloš , Gupta Richa , Lee Beatrice J. Y. , Young Rowan D.
Published: November 2023

A method of desymmetrization of geminal difluoroalkanes using frustrated Lewis pair (FLP) mediated monoselective C–F activation where a chiral sulfide is the Lewis base component is reported. The stereoselective reaction provides generally high yields of diastereomeric sulfonium salts with dr of up to 95:5. The distribution of diastereomers is found to be thermodynamically controlled via facile sulfide exchange. The use of enantiopure chiral sulfides allows for high stereospecificity in nucleophilic substitution reactions and the formation of stereoenriched products.
Deep‐learning based in situ image monitoring crystal polymorph and size distribution: Modeling and validation
Authors: Yao Tuo , Liu Jian , Wan Xuxing , Li Beibei , Rohani Sohrab , Gao Zhenguo , Gong Junbo
Published: November 2023

In situ monitoring and closed‐loop control of the solution crystallization process are the modern trends for pharmaceutical development, in which the critical process parameters (CPPs) as well as the product critical quality attributes (CQAs) can be regulated and guaranteed during the manufacturing process. In this study, an in situ image monitoring methodology based on a state‐of‐the‐art deep‐learning model was developed to track the CQAs such as polymorph ratio, two‐dimensional crystal size, and crystal shape in a solvent‐mediated polymorphic transformation (SMPT) process. Coupled with the multidimensional process information, a 2D population balance model (PBM) was developed and validated using the results of the in situ image‐based CQAs analysis. The 2D‐PBM was solved using a high‐resolution finite volume method (HR‐FVM) which could provide a high dimensional particle‐size distribution. Through the validation between the process image analysis and the 2D‐PBM, the accuracy of image analysis was discussed, and the potential and challenges of in situ image analysis were proposed. This work aims to integrate the crystal polymorphism and two‐dimensional crystal size distribution (2D‐CSD) information in the SMPT process using intelligent microscopic image analysis and then to validate the results of neural network processing by solving the numerical solution of the multidimensional PBM.
Comparative methods for quantifying plasma biomarkers in Alzheimer's disease: Implications for the next frontier in cerebral amyloid angiopathy diagnostics
Authors: Muir Ryan T. , Ismail Zahinoor , Black Sandra E. , Smith Eric E.
Published: November 2023

Plasma amyloid beta (Aβ) and tau are emerging as accessible biomarkers for Alzheimer's disease (AD). However, many assays exist with variable test performances, highlighting the need for a comparative assessment to identify the most valid assays for future use in AD and to apply to other settings in which the same biomarkers may be useful, namely, cerebral amyloid angiopathy (CAA). CAA is a progressive cerebrovascular disease characterized by deposition of Aβ40 and Aβ42 in cortical and leptomeningeal vessels. Novel immunotherapies for AD can induce amyloid‐related imaging abnormalities resembling CAA‐related inflammation. Few studies have evaluated plasma biomarkers in CAA. Identifying a CAA signature could facilitate diagnosis, prognosis, and a safer selection of patients with AD for emerging immunotherapies. This review evaluates studies that compare the diagnostic test performance of plasma biomarker techniques in AD and cerebrovascular and plasma biomarker profiles of CAA; it also discusses novel hypotheses and future avenues for plasma biomarker research in CAA.
Sequence identification and in silico characterization of novel thermophilic lipases from Geobacillus species
Authors: Sürmeli Yusuf , Tekedar Hasan Cihad , Şanlı‐Mohamed Gülşah
Published: November 2023

Microbial lipases are utilized in various biotechnological areas, including pharmaceuticals, food, biodiesel, and detergents. In this study, we cloned and sequenced Lip21 and Lip33 genes from Geobacillus sp. GS21 and Geobacillus sp. GS33, then we in silico and experimentally analyzed the encoded lipases. For this purpose, Lip21 and Lip33 were cloned, sequenced, and their amino acid sequences were investigated for determination of biophysicochemical characteristics, evolutionary relationships, and sequence similarities. 3D models were built and computationally affirmed by various bioinformatics tools, and enzyme‐ligand interactions were investigated by docking analysis using six ligands. Biophysicochemical property of Lip21 and Lip33 was also determined experimentally and the results demonstrated that they had similar isoelectric point (pI) (6.21) and Tm (75.5°C) values as Tm was revealed by denatured protein analysis of the circular dichroism spectrum and pI was obtained by isoelectric focusing. Phylogeny analysis indicated that Lip21 and Lip33 were the closest to lipases from Geobacillus sp. SBS‐4S and Geobacillus thermoleovorans, respectively. Alignment analysis demonstrated that S144–D348–H389 was catalytic triad residues in Lip21 and Lip33, and enzymes possessed a conserved Gly‐X‐Ser‐X‐Gly motif containing catalytic serine. 3D structure analysis indicated that Lip21 and Lip33 highly resembled each other and they were α/β hydrolase‐fold enzymes with large lid domains. BANΔIT analysis results showed that Lip21 and Lip33 had higher thermal stability, compared to other thermostable Geobacillus lipases. Docking results revealed that Lip21‐ and Lip33‐docked complexes possessed common residues (H112, K115, Q162, E163, and S141) that interacted with the substrates, except paranitrophenyl (pNP)‐C10 and pNP‐C12, indicating that these residues might have a significant action on medium and short‐chain fatty acid esters. Thus, Lip21 and Lip33 can be potential candidates for different industrial applications.
Investigation of the mechanisms for wireless nerve stimulation without active electrodes
Authors: Smith Luke A. , Bem Jaedon D. , Lv Xiaojing , Lauto Antonio , Sliow Ashour , Ma Zhiyuan , Mahns David A. , Berryman Carolyn , Hutchinson Mark R. , Fumeaux Christophe , Tettamanzi Giuseppe C.
Published: November 2023

Electric‐field stimulation of neuronal activity can be used to improve the speed of regeneration for severed and damaged nerves. Most techniques, however, require invasive electronic circuitry which can be uncomfortable for the patient and can damage surrounding tissue. A recently suggested technique uses a graft‐antenna—a metal ring wrapped around the damaged nerve—powered by an external magnetic stimulation device. This technique requires no electrodes and internal circuitry with leads across the skin boundary or internal power, since all power is provided wirelessly. This paper examines the microscopic basic mechanisms that allow the magnetic stimulation device to cause neural activation via the graft‐antenna. A computational model of the system was created and used to find that under magnetic stimulation, diverging electric fields appear at the metal ring's edges. If the magnetic stimulation is sufficient, the gradients of these fields can trigger neural activation in the nerve. In‐vivo measurements were also performed on rat sciatic nerves to support the modeling finding that direct contact between the antenna and the nerve ensures neural activation given sufficient magnetic stimulation. Simulations also showed that the presence of a thin gap between the graft‐antenna and the nerve does not preclude neural activation but does reduce its efficacy.
Recent Advances in the Development of Li‐Air Batteries, Experimental and Predictive Approaches – Prospective, Challenges, and Opportunities
Authors: Jilani Aisha , Awan Zahoor , Taqvi Syed Ali Ammar , Khan Firoz , Alshahrani Thamraa
Published: November 2023

The significance of lithium‐air batteries (LABs) has recently increased as they are a highly competitive alternative to lithium‐ion batteries (LIBs) for powering electric automobiles. The reason behind this is their excessive theoretical energy density. The advancement, breakthroughs, and drawbacks of LABs are examined. A comprehensive evaluation of various energy storage devices is provided, followed by an evaluation of several electrochemical storage technologies, their advantages, and drawbacks. Also, recent advances in LABs are reviewed and potential machine learning techniques are explored to address the existing obstacles hindering the widespread adoption of LABs.
Zuverlässige Druckmessung in der Wasserstoffproduktion
Authors: Hermann Alexander
Published: November 2023

Messer Industriegase ist ein familiengeführtes, global aktives Unternehmen für Industrie‐, Medizin‐ und Spezialgase. Am Standort Castrop‐Rauxel erzeugt Messer seit 2020 stündlich 2.700 Nm3 Wasserstoff in einem Dampfreformer. In der Anlage gibt es viele Sicherheitseinrichtungen, bei der die Druckwerte eine entscheidende Rolle spielen. Hier kommen Messgeräte von Endress+Hauser zum Einsatz, die den Herausforderungen der Wasserstoffproduktion gerecht werden, u.a. durch eine goldbeschichtete Membran.
Wirtschaft + Produktion
Authors: Gandert Etwina
Published: November 2023

Innovative Lösungswege für eine CO2‐arme Welt und Vorbericht zur Fachmesse SPS
A linear low effort stabilization method for the Euler equations using discontinuous Galerkin methods
Authors: Bänsch Michel , Behrens Jörn , Vater Stefan
Published: November 2023

We present a novel and simple yet intuitive approach to the stabilization problem for the numerically solved Euler equations with gravity source term relying on a low‐order nodal Discontinuous Galerkin Method (DGM). Instead of assuming isothermal or polytropic solutions, we only take a hydrostatic balance as a given property of the flow and use the hydrostatic equation to calculate a hydrostatic pressure reconstruction that replaces the gravity source term. We compare two environments that both solve the Euler equations using the DGM: deal.II and StormFlash. We utilize StormFlash as it allows for the use of the novel stabilization method. Without stabilization, StormFlash does not yield results that resemble correct physical behavior while the results with stabilization for StormFlash, as well as deal.II model the fluid flow more accurately. Convergence rates for deal.II do not match the expected order while the convergence rates for StormFlash with the stabilization scheme (with the exceptions for the L errors for momentum) meet the expectation. The results from StormFlash with stabilization also fit reference solutions from the literature much better than those from deal.II. We conclude that this novel scheme is a low cost approach to stabilize the Euler equations while not limiting the flow in any way other than it being in hydrostatic balance.