bluuebunny/crossref_metadata_2025 huggingface dataset:
DIGITALIZATION OF ECONOMIC AND LOGISTICS SYSTEMS: CREATION AND IMPLEMENTATION OF A CLUSTER HUB
Authors: KOLIADENKO Svitlana
Published: April 2024

The study includes an analysis of the theoretical aspects of digitization, definition of the concept of the cluster hubs, as well as consideration of the possibilities of their implementation to increase competitiveness and optimization of logistics processes.

The article analyzes the modern interpretation of definitions common in the economic scientific environment: digitization, a systematic approach to the study and implementation of digitization advantages in practical activities, digitization of economic and logistics systems as separate categories and their interconnection in one structural component, the logistics hub; the introduction into the economic use of the term «cluster hub» for the logistics complex is substantiated and the option of its creation for Ukraine is proposed, taking into account the current military situation in the country and the post-war revival of its economy.

The impact of the modern military and related crisis in the economy of Ukraine on business entities as a consequence of russia’s military aggression is substantiated, which requires the search for new ways of exiting the country’s economy from the current situation.

It was determined that the development of the post-war economy of Ukraine cannot occur as a change of the individual subjects, but only in a holistic system of such development, where economic and logistical connections can be managed only in its (system) composition. The system is regulated by modern IT technologies, business process models, information communications, etc.

It was determined that the movement of large volumes of goods in the modern wartime, and in the near future in the postwar period, is not possible by conventional means. The previously regulated logistic ways of movement do not correspond to the situation, therefore the use of the latest tools, methods, methods of digitization and IT technologies are important ways of solving the issues.

The directions of the digitalization system solution to the problem of delivery, movement of goods, in particular, the creation of a logistics hub (including a cluster hub) that will contribute to the combination of elements of the economic and logistics system are identified: the creation of such a hub on the basis of the airport near the city of Vinnytsia.
ESTABLISHMENTS OF THE THIRD WAVE RESTAURANT INDUSTRY: STATE AND PERSPECTIVES
Authors: BEZRUCHENKO Yurii , SCHUKA Galina
Published: April 2024

The article explores contemporary trends in the restaurant business, specifically in the context of the development of third-wave restaurant establishments. The article analyzes the influence of innovations and technologies on the gastronomic industry, compares third-wave restaurants with traditional restaurant establishments, and identifies key differences in their organization and operation.

The authors examine the use of innovative technologies such as artificial intelligence, data analytics, and automated management systems. Examples of the application of these technologies in the restaurant business are provided, including demand analysis, inventory management, and customer recommendations. The article discusses the difference between third-wave restaurants and traditional establishments in choosing culinary concepts and approaches to menu formation. The authors emphasize the individualized approach to cooking technology and the introduction of the innovative dishes in third-wave restaurant enterprises, characterized by a deeper understanding of modern gastronomic trends and customer preferences.

A shift in focus towards individualized service and active interaction with guests through social networks is noted in third-wave restaurant establishments, compared to the potentially more formal approach of traditional establishments. The role of third-wave hospitality establishments in implementing sustainable development concepts is considered.

In conclusion, the authors express the belief that third-wave restaurant establishments have the potential not only to transform the gastronomic landscape but also to become key contributors to the development of the restaurant business in Ukraine. It is noted that their innovations and technological approach can set new standards for service, menu diversity, and attitudes toward environmental impact. The article concludes by highlighting the need for the further research in this area and the prospects for the development of the restaurant business in Ukraine in the face of the growing popularity of third-wave restaurant establishments.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN KURANG ENERGI KRONIS (KEK) PADA IBU HAMIL
Authors: Wahab Irwana , Fitriani Aida , Wahyuni Yenni Fitri , Mawarni Serlis
Published: April 2024

Abstrak

Latar Belakang: Kurang energi kronik (KEK) merupakan kondisi ibu hamil yang mengalami kekurangan makanan telah berlangsung menahun (kronis) dan menimbulkan gangguan kesehatan serta berdampak komplikasi pada ibu dan janin.

Tujuan: Menganalisis hubungan antara faktor usia, paritas dan IMT dengan kejadian KEK pada ibu hamil di Puskesmas Syamtalira Bayu.

Metode: Penelitian ini menggunakan desain penelitian cross sectional pada ibu hamil yang melakukan pemeriksaan ANC pada bulan Oktober hingga Desember 2021 ke Puskesmas Syamtalira Bayu. Sampel berjumlah 30 orang. Analisis menggunakan uji Mann-Whitney.

Hasil: Hasil analisis univariat karakteristik responden terbanyak dari usia yaitu tidak berisiko (97%),. paritas yaitu nulipara (50%) dan IMT normal (80%). Hasil analisi bivariat dari faktor usia dan paritas menunjukkan hasil tidak berhubungan dengan kejadian KEK (p value lebih dari 0,05). Sedangkan faktor IMT ibu hamil memiliki hubungan dengan kejadian KEK (p value = 0,001).

Kesimpulan: Dari tiga faktor yang diteliti didapatkan hanya satu faktor yaitu IMT yang berhubungan dengan kejadian KEK pada ibu hamil. Penelitian berikutnya dapat menggunakan pelibatan jumlah sampel yang lebih besar dan selektif dengan menetapkan kriteria sampel.

 

Kata kunci: Kekurangan energi kronis; usia; paritas; IMT; Ibu hamil
GAMBARAN PENGETAHUAN, SIKAP DAN KESIAPAN MAHASISWA ILMU KESEHATAN DALAM PENERAPAN EVIDENCE BASED PRACTICE (EBP)
Authors: Pranata Gst. Kade Adi Widyas , Wulandari Ida Ayu Putri
Published: April 2024

Banyak konsekuensi buruk yang mungkin terjadi jika praktik layanan kesehatan tidak berbasis bukti. Namun, pengenalan dan penyertaan konsep EBP dalam kurikulum mahasiswa ilmu kesehatan di negara berkembang seperti Indonesia belum terlaksana secara maksimal. Banyak di antara mereka bahkan dilaporkan tidak mampu mencari literature. Oleh karena itu, sebagai landasan penyempurnaan kurikulum, pengukuran pengetahuan, sikap, dan kesiapan mahasiswa ilmu kesehatan terkait penerapan EBP sangat penting untuk ditelusuri lebih jauh. Desain penelitian ini adalah survei deskriptif cross-sectional. Penelitian ini dilakukan secara online terhadap 369 mahasiswa kesehatan di Bali, Indonesia tahun 2021. Adapun kuisioner yang digunakan dalam mengukur tiga variable independent adalah EBPQ (Evidence-Based Practice Questionnaire) versi bahasa Indonesia. Uji analisis deskriptif dengan bantuan SPSS 20 for Windows digunakan sebagai teknik analisa data. Sebagian besar responden berjenis kelamin perempuan (86,2%) dan merupakan mahasiswa keperawatan (70,2%). Sebagian besar dari mereka secara subyektif menyatakan memiliki pengetahuan yang baik (65.2±14.9; 87.3%), sikap mendukung (20.2±4.4; 92.9%), dan kesiapan yang baik (24.8 ± 8.1; 69.1%) dalam penerapan praktik berbasis bukti. Temuan-temuan ini dapat menjadi landasan bagi perubahan atau penyempurnaan kurikulum pendidikan tinggi ilmu kesehatan.
Cancer stem cell, chromosomal instability, and cancer immunity
Authors: Kumari Laxmi , Munjal Saloni , Yadav Reena , Kumar Yashwant , Bhatia Alka
Published: April 2024

Cancer stem cells (CSCs) are a unique population of tumor cells with stem cell-like properties. They are believed to be involved in drug resistance, potential therapy failure, tumor relapse after treatment, and ultimately reduced overall survival of cancer patients. One of the causal factors that may lead to CSC formation is chromosomal instability (CIN), a dynamic event leading to numerical and structural changes in the chromosomes. The CIN is also proposed to aid the maintenance of CSCs, contribute towards their heterogeneity, and facilitate their immune escape. However, the role of CIN in the modulation of the immune system in tumors remains contradictory. Studies have revealed that it can lead to both activation and suppression of the immune system. Previous literature suggests that the CIN, CSCs, and cancer immunity (3Cs), interact with and complement each other to create a pro-tumor environment. However, the mechanisms underlying such an interaction are poorly understood. So, in this review article, an attempt has been made to understand the nature of the interaction between the triad of CIN, CSC, and the immune response in tumors and some of the pathways governing the same. Understanding the above may be a positive step towards the complete cure for malignant diseases.
Mechanical Properties and Failure Behavior of Epoxy Rubber Powder Composites Reinforced with Hollow Beads
Authors: Zhe Wu , Zhen Zhang , Xinlong Zhang , Haifeng Jiang , Zhongchi Zhang
Published: April 2024

In this paper, new epoxy resin/rubber powder/hollow beads three-phase composites were prepared by designing the incorporation of fly ash hollow beads with different mass fractions (5%, 10%, 15%, and 20%) as new reinforcing phases into epoxy resin/rubber powder two-phase composites with 5% mass fraction of carbon black rubber powder. Quasi-static compression tests were conducted at room temperature to test the compressive properties of the oxygen resin/rubber powder/hollow beads composites. Calculate the energy absorption properties and energy absorption efficiency of the composites from the compression curves. Fracture characteristics of compressed material specimens with microscopic morphology were observed by scanning electron microscopy. By systematically analyzing the effect of fly ash hollow beads content on the mechanical properties of epoxy resin/rubber powder/hollow beads three-phase composites, it was found that fly ash hollow beads as reinforcing materials can effectively improve the brittleness and yield strength of epoxy resin/rubber powder as well as the energy-absorbing properties and efficiency of the composites. The energy absorption properties of the epoxy resin/rubber powder/hollow beads composites increased and then decreased with the increase in the mass fraction of fly ash hollow beads. In the epoxy resin/rubber powder/hollow beads composites, the most significant performance was observed when the mass fraction of fly ash was 10%.
Impact of Polypropylene Sutures Phisical Properties on Lymphaticovenous Anastomosis in Lymphedema Patients
Authors: Bordianu Anca , Grigorean Valentin Titus , Bobirca Anca , Litescu Mircea , Bobirca Florin
Published: April 2024

Polypropylene is a material recognized for its tensile properties, as well as for the stability of its chemical structure, an important element that has allowed the use of this material on a large scale, in a wide range of fields of activity, especially in the medical field. This study aims to highlight the structural properties of polypropylene, which contribute to improving the prognosis of vascular microsutures, through the comparative analysis of the results obtained after performing lymphatico-venous anastomosis in lymphedema patients. The research was focused on analyzing the importance of the diameter of the polypropylene thread and its tensile properties on the patency of the lymphatic anastomosis, through the comparative analysis of two groups of patients who benefited from micro-vascular sutures. The database was made up of a group of 82 patients divided into two groups who benefited from supermicrosurgical interventions by using polypropylene thread 11.0 (37 cases involving 148 anastomoses), respectively 12.0 (45 cases involving 180 anastomoses). The results of the research revealed that the group of patients who benefited from microvascular anastomoses using 12.0 poly-propylene thread recorded both better anastomosis patency rates and a significantly reduced rate of complications due to the rejection reaction of the suture material, under the conditions a significantly reduced tensile strength.
The Performance Investigation of PLLA/PPAPH: The Influence of PPAPH as Heterogeneous Crystal Nuclei
Authors: Zhao Lisha , Lv Yang , Chen Jiale , Huang Hao , Zhou Xiaoqin , Cai Yanhua
Published: April 2024

To overcome PLLA�s poor crystallization capability, using nucleating agent as crystallization improvement strategy was performed in this study. PPAPH as PLLA�s an organic nucleating agent was firstly synthesized, and then PLLA was blended with different PPAPH loading through melting blend method, the resulting influences of PPAPH on PLLA�s performances were investigated using the relevant testing instruments. Melt-crystallization revealed that PPAPH played important role in promoting PLLA�s crystallization through providing effective sites of heterogeneous nucleation, and effect of PPAPH loading on PLLA�s melt-crystallization was very poor, indicating that low PPAPH loading could cause PLLA to possess powerful crystallization capacity. In addition, the relative low final melting temperature was beneficial for PLLA/PPAPH�s crystallization. However, an increase of cooling rate during cooling stage weakened PLLA/PPAPH�s crystallization capacity. PLLA/PPAPH�s cold-crystallization suggested that PPAPH had an inhibition effect on cold-crystallization process to some extent. Melting behaviors depended on heating rate and previous crystallization including melt-crystallization at various cooling rates and isothermal crystallization at various crystallization temperatures. PPAPH enhanced PLLA�s fluidity, tensile modulus and tensile strength. Unfortunately, PLLA�s transmittance was seriously weakened as PPAPH loading increased, as well as the elongation at break continuously decreased.
Assessment of Multilayered Plates with Hyperelastic Coatings Subjected to Dynamic Loadings by Impact at Low Velocities
Authors: Bucur Florina , Matache Liviu-Cristian
Published: April 2024

This paper describes the use of video and digital image processing in investigation of the impact between a rigid hemispherical shape impactor and Hybrid Polyurea-Polyurethane-MWCNTs Nanocomposite Coatings. An experimental study was performed for six sample configurations: single aluminum plates (reference test), multilayer plates with 4 types of coatings and double aluminum plates. The impact phenomenon was recorded with a high-speed video camera and the variation of the projectile s velocity during the impact was obtained through digital analysis. Additionally, the test was instrumented using a force sensor specially designed and mounted on the impactor. The video processing was used to draw the velocity curves and to estimate the evolution of the contact forces between the impactor and the multilayer structures, the results obtained being compared with the force sensor data. Some differences between these two types of measurements are observed, so in order to analyze the configurations behavior, a numerical study of the phenomena was performed in LS-DYNA software using a 2D axial symmetric model. The simulations showed that the profile of the force evolution measured with the sensor is affected by the chosen constructive solution and the data obtained based on the video images are more accurate. The deformations were analyzed, the maximum deformation based on image processing and the residual deformation based on 3D Scan post-test. The video technique combined with 3D Scan are precise enough to study the impact at low velocities and the numerical simulations provide results according to reality. The hyperelastic coatings contribute to a better resistance of the aluminum plates.
PEEK-Polymer for Dental Implants: A Concise Review
Authors: Mitalova Zuzana , Duplak Jan , Duplakova Dariana , Mital Dusan , Litecka Juliana
Published: April 2024

The biomaterials applicable in dental implantology, or implantology generally, are subject to specific requirements, namely biocompatibility, osseointegration, resistance to fracture/ oxidative degradation/ long-term compressive stress/ hydrolisis in boiling water, suitable morphology, suitable physical properties (including mechanical properties), aesthetics, etc. When selecting a suitable material for dental implants, it is also necessary to consider the patient s current health condition and possible complications when placing titanium implants and alloys. If there is a risk of an allergic reaction or hypersensitivity to any of the components of the metal prosthesis, the placement of a semi-crystalline thermoplastic implant - called polyetheretherketone, abbreviated PEEK - is a possible option. Such a wide range of stiffness means that PEEK formulations can be produced with modulus values similar to cortical bone. PEEK is classified as a High Performance Polymer of polymer pyramide (such as Polysulfones polybutylene terephthalate). PEEK can be applied for dental abutment and dental body. This article summarises basic information on the structure and properties of PEEK polymer, advantages/ disadvantages (compared to metal - titanium restorations), application and general information from the examined field.
Development of Smart Agriculture to detect the Arabica Coffee Leaf Disease using IAFSA based MSAB with Channel and Spatial Attention Network
Authors: Saravanakumar Dr. R , Matapurkar Dr. Puneet , Shivakanth Dr. G. , Nassa Dr. Vinay Kumar , Kumar Dr. Santosh , Poonguzhali Dr. S.
Published: April 2024

Plant diseases provide challenges for the agriculture sector, notably to produce Arabica coffee. Recognising issues on Arabica coffee leaves is a first step in avoiding and curing illnesses to prevent crop loss. With the extraordinary advancements achieved in convolutional neural networks (CNN) in recent years, Arabica coffee leaf damage can now be identified without the aid of a specialist. However, the local characteristics that convolutional layers in CNNs record are typically redundant and unable to make efficient use of global data to support the prediction process. The proposed Hybrid Attention UNet, also known as CMSAMB-UNet due to its feature extraction and global modelling capabilities, integrates both the Channel and Spatial Attention Module (CSAM) as well as the Multi-head Self-Attention Block (MSAB). In this study, CMSAMB-UNet is built on Resnet50 to extract multi-level features from plant picture data. Two shallow layers of feature maps are used with CSAM according to local attention. used throughout the feature extraction process to enrich the features and adaptively disregard unwanted features. In order to recreate the spatial feature connection of the input pictures using high-resolution feature maps, two global attention maps produced by MSAB are combined.
Taming Misinformation: Fake Review Detection on Social Media platform using Hybrid Ensemble Technique
Authors: Kalbhor Shraddha , Goyal Dinesh , Sankhla Kriti
Published: April 2024

In today's digital world, we witness exponential growth in the generation of textual content on a daily basis. However, the widespread dissemination of information through social media, online forums, and news websites has given rise to the proliferation of fake views, opinions, and reviews, posing a significant challenge in the battle against misinformation and manipulation. Machine Learning has become increasingly integral to real-world online activities, particularly in the area of Artificial Intelligence. Traditional methods often struggle to keep pace with the relentless creation of internet data. Consequently, short text processing has emerged as a new domain for the application of Machine Learning. This is where sentiment analysis come to the forefront, offering potent tools for discerning the authenticity of online content. Detecting and combating these fabricated sentiments are crucial for preserving the integrity of information and ensuring informed decision-making. This work focus on the previously unexplored area of user comments on review data. By leveraging N-gram technique and hybrid ensemble classification approaches, the research addresses critical issues in fake reviews classification, and sentiment analysis. The aim of this work is to detect fake reviews with limited text using NLP feature extraction, and hybrid ensemble classification algorithms, ultimately contributing to the enhancement of information integrity and decision-making in the digital age.
Flexible and Wearable Antenna Design for Bluetooth and Wi-Fi Application
Authors: Soni Gaurav Kumar , Yadav Dinesh , Kumar Ashok
Published: April 2024

The emergence of wearable technology has revolutionized the way we interact with electronic devices, integrating them into our daily routines. From fitness trackers, smart watches to augmented reality glasses and medical monitoring devices, wearable have become increasingly prevalent. Among the most commonly employed wireless technologies within wearables are Bluetooth and Wi-Fi. The design of efficient and reliable antennas for Bluetooth and Wi-Fi applications in wearable is of paramount importance to ensure optimal performance and user satisfaction. In this paper presented a flexible and wearable antenna design for Bluetooth and Wi-Fi application utilizing the Rogers RT5880 flexible substrate, characterized by a dielectric constant of 2.2 and a thickness of 20mil. The study delves into various analyses of the antenna, including its performance concerning on-body and off-body communication, along with an exploration of the antenna's response to different bending effects. Moreover, the research investigates how the antenna interacts with a human tissue model, providing insights into its behavior and performance in diverse usage scenarios.
Criteria for the Quality of Judicial Decisions in Criminal Proceedings
Authors:   Russian State University of Justice, Moscow, Russia, Kachalova Oksana V. , Belyaev Maksim V. ,   Kazan Branch of the Russian State University of Justice, Kazan, Russia
Published: April 2024

The quality of judicial decisions is one of the main factors according to which the fairness of justice, the activities of the judiciary, as well as the law enforcement system as a whole, and the ability of the state to effectively protect individual rights and freedoms are assessed. The quality of court decisions significantly affects the assessment of the judicial system by society, is an important condition for trust in the court. The purpose of the article is to identify criteria for assessing the quality of decisions made by the court. The methodological basis of the research is the universal dialectical method of scientific cognition, which made it possible to study the subject of research in relation to other legal phenomena, as well as general scientific methods of cognition (analysis, synthesis, induction, deduction, analogy, modeling) and private scientific methods of cognition (formally legal, historical-legal, comparative-legal, concrete-sociological. Conclusions. The quality of judicial decisions in criminal proceedings directly depends on compliance with the requirements imposed on them. Such requirements include legality, reasonableness and fairness. Enforceability, completeness, reliability, consistency, persuasiveness, certainty, unconditionality, transparency, clarity and comprehensibility, correctness are also often considered as criteria for the quality of court decisions. The criteria for the quality of judicial decisions can be contained not only in the norms of the law that define the basic requirements for them – legality, validity, motivation, fairness – but also be in other sources, or even be actually outside the framework of legal regulation (completeness, reliability, consistency, correctness). Evaluation of the quality of solutions should also be carried out in terms of these criteria.
Pelaamalla hyvinvointia?
Authors: Kokkinen Katja , Rutanen Maaret , Luotojoki Tiia
Published: April 2024

Monet huolestuttavat kehityskulut, kuten yksinäisyys ja huoli tulevaisuudesta, nousevat esiin työelämän ja opintojen ulkopuolella olevia nuoria ja nuoria aikuisia koskevissa tutkimuksissa. Samaan aikaan digipelaaminen on yleistynyt. Pelaamista ei kuitenkaan vielä hyödynnetä palveluissa motivoinnin tukena tai työmenetelmänä. Tämän kirjoituksen tavoitteena on kuvata digipelivalmennukseen yhdistetyn hyvinvointivalmennuksen toteuttamista, siitä saatuja kokemuksia sekä valmennukseen osallistuneiden NEET-nuorten (n = 48) tavoitteita valmennukselle ja niiden saavuttamista. Artikkelin aineisto koostuu puolistrukturoiduista alku- ja loppuhaastatteluista, jotka analysoitiin laadullisin menetelmin. Kaikilla valmennuksiin osallistuneilla oli haasteita elämäntavoissaan, ja suurin osa asetti valmennukselle hyvinvointiaan koskevan tavoitteen. Aineistosta tunnistettiin kolme erilaista ryhmää tavoitteiden saavuttamisen ja oman toiminnan osalta: toimijat, pohtijat ja epäröijät. Pelivalmennus ja yhdessä pelaaminen motivoi heitä kaikkia osallistumaan ja sitoutumaan ryhmään. Merkitykselliseksi koettiin huomion kiinnittäminen arjen valintoihin ja onnistumisen kokemukset myös pelattaessa. Tällaisella nykykulttuurin mukaisella mielekkäällä toiminnalla voisi olla jatkossa mahdollisuuksia tavoittaa ja saada NEET-nuoria osallistumaan hyvinvointia tukevaan toimintaan. Ongelmakeskeistä pelipuhetta olisi syytä kääntää kohti pelaamisen tarjoamia mahdollisuuksia.
Pemberdayaan Kampung KB Sekip Jaya Pada Program Dapur Sehat Atasi Stunting
Authors: Budiarta Kustoro , Hidayat Ahmad , Lubis Nurul Wardani , Hasyim Diana
Published: April 2024

Kampung KB Sekip Jaya is prepared as a pilot Kampung KB for stunting prevention. Through the Dapur Sehat Atasi Stunting (DASHAT) programme, Kampung KB Sekip Jaya was implementing a government programme in the form of 100 days to overcome stunting by providing additional nutritionally balanced food to children who are identified as stunted. Together with the Kampung KB Activity Groups (BKB, BKR, BKL and UPPKA), the P3A and P2KB Office of Deli Serdang Regency, the Sekip Village Government and other community groups, the DASHAT programme was implemented as an effort to prevent stunting and build quality families. In its implementation, the DASHAT programme in Kampung KB Sekip Jaya faces various problems, namely: 1) DASHAT management was still conventional so that the 100-day programme to overcome stunting was not supported by the DASHAT work programme, 2) Community empowerment has not been maximised, especially in involving nutritionists and culinary experts, 3) Community empowerment, especially the Activity Group Kampung KB, was not in accordance with its function so that the target of the DASHAT programme was still limited, 4) Human resources involved in the DASHAT programme have low knowledge and understanding of DASHAT management and stunting prevention. The solutions offered through this activity were: 1) training and practice of DASHAT management, 2) training and practice of food production made from local raw materials for each Activity Group Kampung KB as a superior product that sells well.  The method used was partner assistance through training and practice of DASHAT management, training and production practices so that partners have a productive business unit that can be used as a source of financing for the family and for the Kampung KB Sekip Jaya. The results of the activity show that the participants' insights have increased, especially in preparing food menus for 100 days to overcome stunting, the availability of work programs in DASHAT management, the practice of processed marine fish production and the superior product of Kampung KB Sekip Jaya in the form of fish biscuits as a product that will be produced by the UPPKA group as the spearhead of the productive economy in Kampyng KB Sekip Jaya.
Recent clinical trials and optical control as a potential strategy to develop microtubule-targeting drugs in colorectal cancer management
Authors: Kita Katsuhiro , Burdowski Allen
Published: April 2024

Colorectal cancer (CRC) has remained the second and the third leading cause of cancer-related death worldwide and in the United States, respectively. Although significant improvement in overall survival has been achieved, death in adult populations under the age of 55 appears to have increased in the past decades. Although new classes of therapeutic strategies such as immunotherapy have emerged, their application is very limited in CRC so far. Microtubule (MT) inhibitors such as taxanes, are not generally successful in CRC. There may be some way to make MT inhibitors work effectively in CRC. One potential advantage that we can take to treat CRC may be the combination of optical techniques coupled to an endoscope or other fiber optics-based devices. A combination of optical devices and photo-activatable drugs may allow us to locally target advanced CRC cells with highly potent MT-targeting drugs. In this Editorial review, we would like to discuss the potential of optogenetic approaches in CRC management.
Novel subtype of obesity influencing the outcomes of sleeve gastrectomy: Familial aggregation of obesity
Authors: Wang Ze-Yu , Qu Yun-Fei , Yu Tian-Ming , Liu Zeng-Lin , Cheng Yu-Gang , Zhong Ming-Wei , Hu San-Yuan
Published: April 2024

BACKGROUND

Differences in the preoperative characteristics and weight loss outcomes after sleeve gastrectomy (SG) between patients with familial aggregation of obesity (FAO) and patients with sporadic obesity (SO) have not been elucidated.

AIM

To explore the impact of SG on weight loss and the alleviation of obesity-related comorbidities in individuals with FAO.

METHODS

A total of 193 patients with obesity who underwent SG were selected. Patients with FAO/SO were matched 1:1 by propensity score matching and were categorized into 4 groups based on the number of first-degree relatives with obesity (1SO vs 1FAO, 2SO vs 2FAO). The baseline characteristics, weight loss outcomes, prevalence of obesity-related comorbidities and incidence of major surgery-related complications were compared between groups.

RESULTS

We defined FAO as the presence of two or more first-degree relatives with obesity. Patients with FAO did not initially show significant differences in baseline data, short-term postoperative weight loss, or obesity-related comorbidities when compared to patients with SO preoperatively. However, distinctions between the two groups became evident at the two-year mark, with statistically significant differences in both percentage of total weight loss (P = 0.006) and percentage of excess weight loss (P < 0.001). The FAO group exhibited weaker remission of type 2 diabetes mellitus (T2DM) (P = 0.031), hyperlipidemia (P = 0.012), and non-alcoholic fatty liver disease (NAFLD) (P = 0.003) as well as a lower incidence of acid reflux (P = 0.038).

CONCLUSION

FAO patients is associated with decreased mid-to-long-term weight loss outcomes; the alleviation of T2DM, hyperlipidemia and NAFLD; and decreased incidence of acid reflux postoperatively.
Controllable physicochemical properties of WOx thin films grown under glancing angle
Authors: Mandal Rupam , Mandal Aparajita , Dutta Alapan , Sivakumar Rengasamy , Srivastava Sanjeev Kumar , Som Tapobrata
Published: April 2024

In this work, various physicochemical properties are investigated in nanostructured WOx thin films prepared by radio-frequency magnetron sputtering for optoelectronic applications. A glancing angle of 87° is employed to grow films of different thicknesses, which are then exposed to post-growth annealing. Detailed local probe analyses in terms of morphology and work function of WOx films are carried out to investigate thickness-dependent property modulations of the as-deposited and annealed films. The analyses show a reasonably good correlation with photoelectron spectroscopic measurements on the films and the bulk I–V characteristics acquired on a series of WOx/p-Si heterojunction diodes. The presence of a critical WOx thickness is identified to regulate the rectification ratio values at the WOx/p-Si heterostructures and increase in series resistance within the bulk of the films. The present study provides valuable insights to correlate optical, electrical, and structural properties of WOx thin films, which will be beneficial for fabricating WOx-based optoelectronic devices, including photovoltaic cells.
Evaluation of the enantioselectivity of new chiral ligands based on imidazolidin-4-one derivatives
Authors: Bartáček Jan , Chlumský Karel , Mrkvička Jan , Paloušová Lucie , Sedlák Miloš , Drabina Pavel
Published: April 2024

The new chiral ligands I–III based on derivatives of imidazolidin-4-one were synthesised and characterised. The catalytic activity and enantioselectivity of their corresponding copper(II) complexes were studied in asymmetric Henry reactions. It was found that the enantioselectivity of these catalysts is overall very high and depends on the relative configuration of the ligand used; cis-configuration of ligand affords the nitroaldols with major enantiomer S- (up to 97% ee), whereas the application of ligands with trans-configuration led to nitroaldols with major R-enantiomer (up to 96% ee). The “proline-type” ligand IV was also tested in asymmetric aldol reactions. Under the optimised reaction conditions, aldol products with enantioselectivities of up to 91% ee were obtained.
Analisis SWOT Pembelajaran Pendidikan Agama Islam pada Kurikulum Merdeka di Sekolah Penggerak
Authors: Alfarizi Lutfi , Umam Khotibul , Fathiyaturrahmah Fathiyaturrahmah
Published: April 2024

This research aims to identify strengths and weaknesses, as well as opportunities and threats in PAI learning at SMP 11 Ma'arif Bangsalsari Jember. Thus, the school can find appropriate and measurable steps to make decisions. In this study, a qualitative research approach was used with the SWOT matrix analysis method. The data used were taken from respondents who had filled out a questionnaire prepared by the researcher. The data were then grouped based on SWOT aspects and analyzed using the SWOT matrix approach. The results of this study show that in the internal aspect, the independent curriculum gives freedom to PAI teachers to develop a learning process that can be adapted to the needs of students. However, the weakness found is the limited resources and facilities in the institution that greatly affect the learning process. In the external aspect, PAI learning has a wider opportunity to develop Islamic religious values according to individual abilities. However, the threat is that differences in interpretation between teachers can cause conflicts that lead to disunity, which can reduce the intensity and quality of PAI learning. Based on these internal and external aspects, there are several steps that PAI teachers should take. First, teachers need to innovate in PAI learning optimally. Second, teachers need to expand relationships with the community and clerics to improve social competence. Third, PAI teachers must have enthusiasm and continue to improve professionalism in carrying out academic duties. Fourth, teachers need to increase support from the education office and school leadership in facilitating PAI learning activities. Fifth, PAI teachers need to improve their ability and cohesiveness in understanding the implementation of the independent curriculum. Sixth, teachers need to improve quality in the realm of professionalism and understanding of the concept of religious moderation. Seventh, teachers need to be equipped with skills in developing interesting and effective PAI learning for students. Eighth, teachers need to communicate with school leaders and the education office to provide and prepare supporting facilities in PAI learning.
Social Media Platform Slang Language: Learning Indonesian as a Language of Communication in Daily Conversation
Authors: Mayrita Hastari , Indah Sari Ayu Puspita , Ernawati Yeni , Wahyuni Sri
Published: April 2024

This research aims to identify and interpret slang messages used in daily conversations, especially those used among young people, and create material content on the social media platform 'Bahasa Gaul-Bahasa Indonesia.' Instagram is the social media platform used to include the material content of the slang findings from this research. So, the results of the research can be used as a medium for speakers to learn Indonesian, especially the language of daily communication, with the selection of appropriate diction so that communication becomes more efficient and effective. The method used in this research is a qualitative method with a case study approach. The data collection technique used was the document technique. The data is in the form of recordings of the slang vocabulary used by Palembang speakers. The observed utterances were taken randomly for 30 minutes, either in situations in the canteen, in class, with relatives, or in the researcher's neighborhood. The number of utterances obtained was 107 utterances, with 40 speakers. The data analysis technique uses semiotic techniques with a pragmatic approach. The findings in this study are 100 slang words used in Palembang Sari-Sari conversations by Palembang speakers who are the subjects of this study. Then, the results of the findings and analysis are used as content on the Instagram platform of Bahasa Gaul-Bahasa Palembang-Bahasa Indonesia (BBG-Belajar Bahasa Gaul), with the Instagram name @belajar_bahasa_gaul.
The Role of Social Interaction in Improving the Quality of Islamic Religious Education Learning
Authors: Masykuri Hasan Al Banna
Published: April 2024

This research aims to investigate and understand the role of social interaction in improving the quality of Islamic Religious Education learning. This research will explore how social interactions in the classroom context can influence the effectiveness of Islamic religious learning. Apart from that, this research also aims to identify effective social interaction strategies that can be used to improve the quality of Islamic Religious Education learning in Islamic secondary schools. This research uses a qualitative approach with a case study design at Sabilurrosyad Islamic High School Malang, selecting three classes as case units (classes X, XI, and XII). Data was collected through in-depth interviews with teachers and students, as well as direct observations in classrooms to record social interactions between students and Islamic Religious Education teachers. The research location focused on classrooms at the school. The purposive sampling method was used to select research participants. The research findings indicate that instructional models such as group investigation, role-playing, and jurisprudential learning positively impact social interaction and students' understanding of PAI material. The group investigation model allows students to collaborate in identifying and exploring social and moral issues, while role-playing enables students to interact in real-life situations relevant to religious values. Furthermore, jurisprudential learning allows students to understand and integrate religious values in formulating solutions to relevant public policy issues. The role of teachers as facilitators, mentors, academic counselors, and support providers is crucial in facilitating effective social interaction in PAI classes. Support systems, including comprehensive library facilities and access to external school references, are crucial in supporting quality interactive learning. In conclusion, social interaction in the classroom significantly enhances the quality of PAI learning, and instructional approaches that encourage active interaction between students and teachers can shape a better and more accurate understanding of religious teachings.
Competence of Arabic Language Learning Media Lecturers in the Perspective of the Australian Federation of Modern Language Teachers Associations (AFMLTA)
Authors: Putra Wahyu Hanafi , Isnaini Rohmatun Lukluk , Yousry Islam
Published: April 2024

The purpose of the study was to describe the competence of INSURI Ponorogo Arabic learning media lecturers with a standard perspective and teacher professionalism, according to The Australian Federation of Modern Language Teachers Associations (AFMLTA). This research is qualitative and uses a case study approach. Carried out in the INSURI Arabic language education study program. Research data in the form of competence and professionalism of PBA Learning Media lecturers are limited to projections of student receptive ability development through Arabic cartoons accessed from Marhaban Academy Channel on the https://www.youtube.com/@MarhabanAcademy link. The sources of research data are lecturers, students, and learning activities in the classroom. Data collection techniques are carried out by observation, interviews, and documentation. The analysis of research data is carried out by reducing data, presenting data, and drawing conclusions. The results showed, referring to the standards of AFMLTA foreign language teachers. Lecturers of Arabic learning media courses have met AFMLTA standards, namely mastering pedagogic, professional, and social competencies. Pedagogic competence is colored by the ability to manage classes. Professional competence is aimed at the formulation of learning objectives before lecturers step into the learning process. Meanwhile, social competence is aimed at creating a learning atmosphere by adjusting the curriculum and culture of the INSURI Ponorogo campus. Thus, the existence of AFMLTA can measure the competence and professionalism of language teachers outside Australian countries.
FORCE CALCULATION OF THE ABENICS ACTIVE HINGE OF THE MANIPULATOR-MOTOR OF THE MULTI-PURPOSE ROBOTIC PLATFORM
Authors: Zalypka V.
Published: April 2024

It has been established that the prerequisite for multi-purpose robotic platform (MPRP), which determines the use of a manipulator-mover with an active Abenics joint, is, first of all, road conditions (locality), because in field conditions or as a result of missile and artillery damage, such extreme conditions occur when the movement on the main mover is impossible and there is a need to involve auxiliary (additional) mechanisms. The design features of the Abenics technology were analyzed and its advantages in providing three degrees of freedom at one point of contact were clarified. On the basis of the provisions of the theory of machine parts and the Solid Works software, the strength calculation of the Abenics hinge was carried out, namely: allowable contact fatigue stresses 412 MPa, allowable bending stresses 267 MPa; circular Ft 683 N and radial Fr 247,9 N forces in engagement. The transmission was checked for contact stress strength H 407,6 MPa and for the bending strength of the wheel teeth in 41,95 MPa; the torque around the Abenics active joint is determined in Mкрш 136 Nm. The distribution of stresses relative to the faces to which a force of 683 N was applied is graphically presented. The manipulators-movers in which the Abenics active hinge will be used, with the above results, will have a load capacity of 150-200 kg, which makes it possible to evacuate a wounded soldier with equipment or deliver corresponding load on the front edge (firing positions). Thus, the approach proposed by the author can be the basis for the creation of new promising MPRPs with increased operational properties such as passability and stability, because their manipulators will be able, if necessary, to perform the function of a stepping or wheel drive. It is proposed to first of all implement the capabilities of Abenics technology on MPRPs of rear, technical and medical support, which will not require additional stabilization of their hull in comparison with combat and special ground robotic complexes. In the future, the same technology can be applied in the field of mobile robotics, because it allows you to design the connection of links (kinematic pairs) of the manipulator on an active ball joint, that is, at one point, while increasing the efficiency of the operation of the manipulator by reducing the consumption of resources.
MODEL OF FORMATION OF DECISIVE FUNCTION OF COMBINED CORRELATION-EXTREME NAVIGATION SYSTEM USED IN GUIDANCE OF UNMANNED AIRCRAFT
Authors: Sotnikov O. , Tiurina V.
Published: April 2024

The results of development of formalized model of process of formation of decisive function of combined correlation-extreme navigation system of unmanned aerial vehicles are presented. The development of the model is carried out taking into account the state of the operational and tactical situation, as well as the effect of changing the geometry of the sighting. The peculiarity of the developed model consists in the formation of a decisive function using a set of reference images, which is necessary for the formation of a decisive function, the set of reference images is built taking into account changes in navigation parameters of an unmanned aerial vehicle and angular orientation parameters.

The originality of the formalized model consists in the determined order of formation of the decisive function of the combined correlation-extreme navigation system, which, unlike the known ones, consists in step-by-step determination of coordinates of the reference object by clarifying the navigation parameters of unmanned aerial vehicles with subsequent refinement of the angular orientation parameters according to the following sequence: determining the height of formation of the current image, determining the angles of view and determining the angular orientation parameters. Each of the individual reference images corresponds to its own multidimensional matrix of luminance values of the corresponding pixels or radio-thermal temperature. This takes into account the area of objects located on the sighting surface, which leads to refinement of the coordinates of the reference object in the current image.

Changes in the spatial position and orientation of unmanned aerial vehicles, geometric properties of the sighting surface, as well as taking into account variations in informative features of the sighting surface objects depending on external factors and the influence of the medium on the propagation of signals in the optical and radiometric ranges of waves and obstacles, which will reduce or completely eliminate the discrepancy of coordinates of the reference object to the current image determined in advance in the reference image.
The Efficacy of Umbilical Oxytocin Injection in The Management of Retained Placenta
Authors: Odesanya Lydia Olubukola , Onasoga O. A. , Abioye Abigail Adebisi , Adamu-Adedipe Foyekemi Oyebola
Published: April 2024

This study investigates the efficacy of umbilical oxytocin injection in managing retained placenta, a condition posing risks to maternal well-being. Oxytocin's pharmacology, including its mechanism of action and administration routes, is explored, highlighting its role in stimulating uterine contractions and placental expulsion. Evidence from studies supports oxytocin's effectiveness and safety in treating retained placenta. Implications for midwives' practice are discussed, emphasizing the importance of timely recognition, proper administration, and close monitoring during oxytocin use. Midwives' involvement in educating women, collaborating with healthcare teams, and ensuring comprehensive care underscores their vital role in managing retained placenta and promoting positive birth outcomes.