bluuebunny/crossref_metadata_2025 huggingface dataset:
Technology of Using Linguistic Markers in the Process of Art Therapy Training
Authors: Sergeeva Marina Georgiyevna , Kochin Andrei Anatolievich , Lukashenko Dmitry Vladimirovich , Kozhina Ekaterina Vladislavovna
Published: August 2021

The article examines the issues of students’ reflexivity, the impact of the reflexivity on the educational process and psychological health, the importance of its development. The purpose of the article is the theoretical and empirical study of students’ reflexivity through its expression in various linguistic markers, the importance of reflexivity in the personal and potential professional development of students. The research methodology and its algorithm were selected due to the purpose of the study. Experimental work included a complex psychological and pedagogical experiment, diagnosing the stated parameters and their subsequent statistical analysis. The study of students’ reflexivity was carried out on the basis of the Institute of Foreign Languages of the Federal State Autonomous Educational Institution of Higher Education “The Peoples’ Friendship University of Russia ”(RUDN). Research sampling: reports (essays) of the 1-4 year students. The target group consisted of 98 students, divided into seven subgroups. The results of the study allowed us to conclude that there is a significant interdependence between linguistic markers and students’ reflexivity. Psychological health is a necessary and important condition for the full development of a personality. On the one hand, it ensures the adequate fulfillment of social roles, on the other hand, it creates the possibility of continuous personal and professional development throughout life. Supporting psychological health is one of the urgent tasks in the young age, the most important stage in the formation of a personality. Reflexivity of students, appearing in the process of consulting or training work, manifests itself, first of all, in speech processes. Group reflexivity, in turn, is the main method of psychological training, since it helps to comprehend and integrate the ongoing experience.
ANALISIS AKUISISI LINTAS NEGARA (CROSS-BORDER ACQUISITION) DALAM HUKUM PENANAMAN MODAL DI INDONESIA
Authors: Wulansari Beta , Sulistiyono Adi
Published: August 2021

Abstract
This article aims to determine the legal basis of cross-border acquisition of companies based on investment law in Indonesia. The type of research is doctrinal (normativewith ekplanatoris research. The approach used in this study were statute approach with the primary legal materials and secondary law. The method legal materials’ collection and the analysis technicque in this article were a literature study and analysis techniques and the that I uses were the method of syllogism and interpretation by using deductive mindset. Cross-border acquisition by a business entity in the country by a business entity abroad are subject to the laws of the country that becames domicile enterprises expropriated, because cross-border acquisition is done outside the jurisdiction of Indonesia, so that the applicable law is the law in the country of the acquisition target company. This is in accordance with Article 5 of Law No. 25 of 2007 on Investment. Cross-border acquisition unlock insights and ideas for doing investment law reform becomes more clear and explicit. So that the purpose of the control and ownership of the acquisition target company is not detrimental to the company being acquired.

Keywords: Acquisition of Cross Country, Investment Law, Shareholders

Abstrak
Artikel ini  bertujuan untuk  mengetahui landasan yuridis perusahaan  cross-border  acquisition sesuai dengan hukum penanaman modal di Indonesia. Jenis penelitian adalah doktrinal (normatif) dengan sifat penelitian ekplanatoris. Pendekatan penelitian  yang digunakan  pendekatan undang-undang  (statute approach) dengan bahan hukum primer dan bahan hukum sekunder. Teknik pengumpulan bahan hukum dalam penulisan ini adalah studi kepustakaan serta teknik analisis yang penulis gunakan adalah dengan metode silogisme dan interpretasi dengan menggunakan pola berpikir deduktif. Tindakan akuisisi lintas negara (cross-border acquisition) oleh suatu badan usaha di dalam negeri oleh suatu badan usaha di luar negeri tunduk pada hukum negara yang menjadi domisili badan usaha yang diambilalih, karena tindakan akuisisi lintas negara (cross-border acquisition) tersebut dilakukan di luar yurisdiksi Indonesia maka hukum yang berlaku adalah hukum yang berada di negara perusahaan target akuisisi. Ini sesuai dengan Pasal 5 Undang-Undang Nomor 25 Tahun 2007 tentang Penanaman Modal. Akuisisi lintas negara (cross-border acquisition) membuka wawasan dan pemikiran bagi dilakukannya pembaharuan hukum penanaman modal menjadi lebih  jelas  dan  tegas. Sehingga  supaya  tujuan untuk  pengendalian dan kepemilikan saham dari perusahaan target akuisisi tidak merugikan pihak perusahaan yang diakuisisi.

Kata Kunci: Akuisisi Lintas Negara, Hukum Penanaman Modal, Pemegang Saham
PRAKTEK HUKUM PENENTUAN GANTI RUGI OLEH HAKIM SEBAGAI AKIBAT ADANYA GUGATAN WANPRESTASI PADA KASUS HUTANG PIUTANG ATAU TUNTUTAN MEMBAYAR SEJUMLAH UANG DI PENGADILAN NEGERI SURAKARTA
Authors: Winarto Th. Wahyu , Purwadi Hari , Novianto Widodo T
Published: August 2021

Abstract
This article aims to know the components and standards what is used and what legal practice used by judge District Court of Surakarta to determine punitive damages based on tort lawsuits in the dispute a debt receivable or pay an amount of money. The article is the juridical normative research. That the practice of law determining the indemnity by the judge as a result of any such tort lawsuits in case of debts receivable or demands payment of a sum of money in the District Court of Surakarta, that conclusion can be obtained in determining his little big compensation is required, the judge uses standard components and such indemnity as provided for in Article 1243 until 1252 The Book Of Civil Law (KUHPerdata) and the law is rooted in the jurisprudence. So that legal considerations in the verdict, a very dry atmosphere of juridical, sociological and philosophical. Recommendation in the context of the discovery of the law by the judge, in order to provide authoritative legal verdict, then required the preparation of material different methods of determining the law regarding the determination of the damages, and legal discovery method as a reference for judges in carrying out tasks mandated laws.

Keywords : Indemnity, Tort Lawsuit, Debt Receivable
           
Abstrak
Artikel ini bertujuan untuk mengetahui komponen-komponen dan standar apa yang dipakai dan apa Praktek  hukum yang  dipakai oleh hakim  Pengadilan  Negeri  Surakarta  untuk  menentukan ganti rugi yang didasarkan pada gugatan wanprestasi dalam sengketa hutang piutang atau tuntutan membayar sejumlah uang. Artikel ini adalah penelitian yuridis normatif. Dalam menentukan besar kecilnya ganti rugi yang dituntut, hakim menggunakan komponen dan standar ganti rugi seperti seperti yang diatur dalam Pasal 1243 sampai dengan 1252 KUHPerdata dan hukum yang digunakan adalah yang dianut dalam yurisprudensi. Sehingga pertimbangan-pertimbangan  hukum dalam  putusan tersebut, sangat kering oleh hakim, agar dapat menghasilkan putusan hukum yang berwibawa, maka diperlukan penyusunan materi  berbagai  metode  penentuan  hukum mengenai  Praktek  penentuan  ganti  rugi,  dan  sekaligus metode penemuan hukum sebagai acuan bagi para hakim dalam menjalankan tugas yang diamanatkan undang-undang.  

Kata Kunci : Ganti Rugi, Gugatan Wanprestasi, Hutang Piutang
IMPLEMENTASI UPAH MINIMUM KABUPATEN BOYOLALI TERHADAP PEKERJA/BURUH PADA USAHA KONVEKSI BERDASARKAN UNDANG-UNDANG RI NOMOR 13 TAHUN 2003 TENTANG KETENAGAKERJAAN
Authors: Rachmawati Lucia , , Isharyanto , Winarno Djoko Wahju
Published: August 2021

Abstract
Wages are the rights of laborers/workers received in return from the employer or employers for a job and/or services that have been or will be implemented. Minimum standards are used by employers to provide wages to laborers/workers are minimum wage. This article  aim to know Implementation of Minimum Wages Boyolali Regency to laborers/workers on the Convection Based on the Law Republic of Indonesia Number 13 Year 2003 about Employement.  This research is a socilogical/empirical legal that is eksplanatif (explain).  Research locations are some convections in Teras and sorounding in  Boyolali Regancy, and The office for cooperatives and labor Boyolali Regancy. Based on this research obtained the results of that Implementation of Minimum Wages Boyolali Regency to laborers/workers on the Convection Based on the Law Republic of Indonesia Number 13 Year 2003 about Employement not run optimally.
Key words: Minimum Wage; Laborers/Workers; Employement Inspection, Welfare

Abstrak
Upah merupakan hak pekerja/buruh yang diterima sebagai imbalan dari pengusaha atau pemberi kerja atas suatu pekerjaan dan/atau jasa yang telah atau akan dilaksanakan. Standar minimum
yang digunakan pengusaha untuk memberikan upah kepada pekerja/buruh adalah upah minimum. Artikel ini bertujuan untuk mengetahui implementasi Upah Minimum Kabupaten Boyolali terhadap pekerja/buruh pada usaha konveksi berdasarkan Undang-Undang RI No. 13 Tahun 2003 tentang Ketenagakerjaan. Penelitian ini adalah penelitian hukum sosiologis/penelitiam hukum empiris yang bersifat eksplanatif (menerangkan). Lokasi penelitian adalah beberapa usaha konveksi di Teras dan sekitarnya di Kabupaten Boyolali, dan Dinas Koperasi dan Tenaga Kerja Kabupaten Boyolali. Berdasarkan penelitian ini diperoleh hasil bahwa Implementasi Upah Minimum Kabupaten Boyolali Terhadap Pekerja/Buruh Pada Usaha Konveksi Berdasarkan Undang-Undang RI Nomor 13 Tahun 2003 Tentang Ketenagakerjaan belum berjalan secara optimal.
Kata kunci: Upah Minimum; Pekerja/Buruh; Pengawasan Ketenagakerjaan, Kesejahteraan
PENYELUNDUPAN HUKUM PERKAWINAN BEDA AGAMA DI INDONESIA
Authors: Ade Witoko Prasetyo , Budhisulistyawati Ambar
Published: August 2021

Abstract  
This article aims to find out about interfaith marriage arrangements carried out through legal  smuggling in Indonesia. This study is a descriptive doctrinal legal research. Data sources from this article are in the form of primary legal material and secondary legal material. The technique of collecting legal material in this article is the library study technique. The approach in this  research is the legislative approach. The result of the article is that marriage according to the  Marriage Law is a marriage carried out according to each religion and belief. So that marriage is considered valid if according to the religion and beliefs of each prospective husband and wife is also valid. Every religion cannot authorize interfaith marriages, because all religions want their followers to marry the same religion, it can be concluded that interfaith marriages are not legal, because they are not in accordance with the contents of the Marriage Law, namely marriage is valid if carried out according to each religion -one, then avoidance of the law that should apply or can be said to be an act of legal smuggling.
Keywords: Marriage; Different Religion Marriage; Law Smuggling

Abstrak
Artikel ini bertujuan untuk mengetahui mengenai pengaturan perkawinan beda agama yang  dilakukan melalui penyelundupan hukum di Indonesia. Penelitian ini adalah penelitian hukum doktrinal bersifat deskriptif. Sumber data dari artikel ini yaitu berupa bahan hukum primer dan bahan hukum sekunder. Tehnik pengumpulan bahan hukum dalam artikel ini adalah tehnik studi kepustakaan. Pendekatan dalam penilitian ini adalah pendekatan perundang-undangan. Hasil artikel yaitu perkawinan menurut Undang-Undang Perkawinan adalah perkawinan yang dilaksanakan menurut agama dan kepercayaan masing-masing. Sehingga perkawinan dianggap sah jika menurut agama dan kepercayaan masing-masing calon suami istri tersebut juga sah. Setiap agama tidak bisa mengesahkan perkawinan beda agama, karena semua agama menginginkan umatnya untuk menikah dengan yang seagama, maka dapat disimpulkan bahwa perkawinan beda agama tidak sah, karena tidak sesuai dengan isi Undang-Undang Perkawinan yaitu perkawinan adalah sah apabila dilaksanakan menurut agama dan kepercayaan masing-masing, maka dilakukan penghindaran terhadap hukum yang seharusnya berlaku atau dapat dikatakan sebagai tindakan penyelundupan hukum.
Kata Kunci : Perkawinan; Perkawinan Beda Agama; Penyelundupan Hukum
KONSTITUSIONALITAS KEBIJAKAN NEW NORMAL DALAM PERLINDUNGAN HAK HIDUP WARGA NEGARA
Authors: Vanesa Hariyanto Ruth Crista
Published: August 2021

Abstract

This study aims to answer two problems: first, outlining the correlation of the Right to Life with Economic Rights in New Nornal Policy; and  secondly, analyzing theConstitutionality of New Normal Policy. The policy created during the Covid-19 Pandemic not infrequently reaping contracdictions. Especially the last one echoed by the governments is the existence of a New Normal Policy which is actually considered unconstitutional because with this policy the government is felt to have ignored the right of Right to Life of citizen and priorited Economic Right. For this reason, this article uses natural law theory as a means of interpretation of two existing problems. In accordance with this, this acricle argues that the New Normal Policy is a constitutional policy because it is in accordance with the spirit of Article 28A UUD NRI 1945.

Keywords: Human Rights, New Normal, Public Policy, Constitutionalism.

Abstrak

Penelitian ini bertujuan untuk menjawab dua permasalahan: pertama, menguraikan korelasi Hak untuk Hidup dengan Hak Ekonomi dalam Kebijakan Nornal Baru; dan kedua, menganalisis Konstitusionalitas Kebijakan Normal Baru. Kebijakan yang dibuat saat Pandemi Covid-19 tak jarang menuai kontradiksi. Terlebih yang terakhir digaungkan oleh pemerintah adalah adanya New Normal Policy yang justru dinilai inkonstitusional karena dengan kebijakan ini pemerintah dirasa telah mengabaikan hak atas Hak Hidup warga negara dan mengutamakan Hak Ekonomi. Untuk itulah, artikel ini menggunakan teori hukum kodrat sebagai alat interpretasi dari dua masalah yang ada. Sejalan dengan hal tersebut, acricle ini berpendapat bahwa New Normal Policy merupakan kebijakan konstitusional karena sesuai dengan semangat Pasal 28A UUD NRI 1945.

Kata Kunci: Hak Asasi Manusia, Normal Baru, Kebijakan Publik, Konstitusionalisme.
Method for Determining the Optimum Insulation Thickness of the Plaster Tow Material: Influence of the Heat Exchange Coefficient in Transient Regime
Authors: TRAORE Papa Touty , BA Fatimata , DIONE Babou , DIENG Moussa
Published: August 2021

In this paper, we have applied a numerical method to determine the optimum insulation thickness of the tow plaster plane material. The influence of the exchange coefficients at the level of the two faces of the material has been highlighted. The optimum insulation thickness of the material is at the area where the thermal resistance value of the material is the maximum. We added the relative thermal resistance to show how the optimum insulation thickness changes when the exchange coefficients change values.
Modeling of MoS2 Tunnel Field Effect Transistor in Verilog-A for VLSI Circuit Design
Authors: Khan Md Azmot Ullah , Adesina Naheem Olakunle , Xu Jian
Published: August 2021

This paper presents the design of an inverter, half adder, and ring oscillator using compact models of MoS2 channel-based tunnel field effect transistor (TFET). The TFET models (both n and p-type) are written in high-level hardware language Verilog-Analog (Verilog-A) following the analytical model of [1] and the output characteristics of the components are simulated in Cadence/Spectre software. The performance of the designed inverter (a basic building block of VLSI circuit) is analyzed by extracting its different parameters, such as transfer characteristics, power dissipation and consumption, delay, power delay product. The simulated outputs (sum & carry) obtained from the half adder circuit exactly match the truth table of the circuit. Moreover, our observation reveals that the ring oscillator can operate at a higher frequency with lower power consumption in comparison to the existing CMOS and GFET technologies. We have also reported an improvement to the limiting factor of ring oscillator performance i.e. phase noise at two different offset frequencies. With all the output characteristics obtained from the commercial software simulation, we expect our model to be applicable to a real-time low-power VLSI circuit.
Cost-Effectiveness Analysis of Genomic Profiling in Early Breast Cancer in Colombia
Authors: Rojas Leonardo , Rojas-Reyes María , Rosselli Diego , Cardona Andres F.
Published: August 2021

Background: In Colombia, the best strategy to establish indication for adjuvant chemotherapy in early breast cancer (EBC) remains unknown. This study aimed to identify the cost-effectiveness of various strategies to establish the necessity of adjuvant chemotherapy.Methods: This study used an adapted decision-analytic model to compare cost and outcomes of care that includes Oncotype DX™ (ODX) or Mammaprint™ (MMP) tests with routine care without ODX or MMP tests (adjuvant chemotherapy for all patients) over a 5-year time horizon from the perspective of the Colombian National Health System (NHS; payer). Data were obtained from published literature and clinical trial database. The study population comprised women with hormone-receptor-positive (HR+), HER2-negative, lymph-node-negative (LN0) EBC with high-risk clinical criteria for recurrence. The outcome measures were incremental cost-effectiveness ratio (ICER; 2019 United States dollar per quality-adjusted life-year [QALY] gained) and net monetary benefit (NMB).Results: ODX increases QALYs by 0.05 and MMP by 0.03 with savings of $2,445 and $570 compared with the standard strategy, respectively. ICER for ODX was −$41,857 and that for MMP was −$18,253 per QALY; NMB was $2,821 and $771, respectively. Both tests were cost-effective under the defined threshold. When the two tests were compared, ODX was more cost-effective than MMP. Sensitivity analysis revealed that with a threshold of 1 gross domestic product per capita, ODX will be cost-effective in 95.5% of the cases compared with 70.2% cases involving MMP. Probabilistic sensitivity analysis revealed that ODX was a consistently superior strategy.Conclusions: Genomic profiling using ODX or MMP tests to define the need of adjuvant chemotherapy treatment in patients with HR+ and HER2− EBC is a cost-effective strategy that allows Colombian NHS to maintain budget.
Comprehensive Genomic And Epigenomic Analyses on Transcriptomic Regulation In Stomach Adenocarcinoma
Authors: Chen Junxing , Liu Weinan , Du Jiabin , Wang Pengcheng , Wang Jintian , Ye kai
Published: August 2021

DNA copy number variations (CNVs) and alterations in methylation (MET)-induced transcriptomic dysregulation plays an important role in promoting heterogeneous Stomach adenocarcinoma (STAD) progression. However, the association between DNA MET and CNVs, and the effect of this association during cancer development remain unknown. Altogether 313 STAD specimens had been extracted to examine DNA MET and copy numbers, and to measure messenger RNA (mRNA) expression (EXP). According to our results, copy-number-correlated (CNVcor) genes were remarkably co-regulated with MET-correlated (METcor) ones. Additionally, CNVcor and METcor genes were carried out multi-omics integration, and 3 STAD prognostic subtypes had been identified and verified using the independent data. Typically, the subtype that had higher aggressiveness was found to be associated with reduced PIK3CA, ARID1A, SPECC1, ZFHX3, KMT2D, OBSCN, ZBTB20, FSIP2, RANBP2 and TTN mutation rates, as well as increased JPH3, PLCXD3, and KCNB1 expression. Our results suggested that above mentioned genes played vital parts during invasive STAD development. And results of this comprehensive analyses on transcriptomic regulation at genomic and epigenetic levels facilitate to understand STAD pathology at various points of view, and assist in developing the effective STAD treatment.
A Comprehensive Social Matrix Factorization with Social Regularization for Recommendation Based on Implicit Similarity by Fusing Trust Relationships and Social Tags
Authors: Chen Rui , Zhang Jianwei , Zhang Zhifeng , Chang Yan-Shuo , Gao Jingli , Li Pu , Liang Hui
Published: August 2021

Social relationships play an important role in improving the quality of recommender systems (RSs). A large number of experimental results show that social relationship-based recommendation methods alleviate the problems of data sparseness and cold start in RSs to some extent. However, since the social relationships between users are extremely sparse and complex, and it is difficult to obtain accurately user preference model, thus the performance of the recommendation system is affected by the existing social recommendation methods. In order to accurately model social relationships and improve recommendation quality, we use explicit social relationships such as user-item ratings, trust relationships and implicit social relationships such as social tags to mine potential interest preferences of users and propose an improved social recommendation method integrating trust relationship and social tags. The method map user features and item features to the shared feature space by using the above social relationship, respectively, and obtains user similarity and item similarity through potential feature vectors of users and items, and continuously trains them to obtain accurate similarity relationship to improve the recommendation performance. Experimental results demonstrate that our proposed approach achieves superior performance to the other social recommendation approaches.
Segmental Variability of Precipitation In The Mahanadi River Basin During 1901-2017
Authors: Sahu Ramgopal Tilakram , Verma Mani Kant , Ahmad Ishtiyaq
Published: August 2021

Eigen-based sequential spatial pattern analysis an application of PCA is presented here. The analysis examines the spatial distribution of precipitation over the Mahanadi river basin. The Spatial(S)-mode of sequential spatial pattern analysis with the application of Maximum loading value of rotated retained principal component (also referred to as Maximum loading value approach) to assess a gridded monthly rainfall data of resolution 0.25° x 0.25° having a record length of 117 years (1901-2017). The meteorological records have a sequential spatial field for Spatial and Temporal-mode, which can be used for recognizing the area for precipitation variability and regime. The identified patterns of the different timeslot segments were then analyzed for their dispersions of the annual precipitation observed at different station points using similarities and dissimilar characteristics of inter-cluster and between clusters respectively. Validation of the regionalized pattern for distinctness and a pairwise comparison of CDFs using the Kolmogorov-Smirnov ‘D’ statistic test.
ITGB2 Expression is Negatively Correlated with the Prognosis of Acute Myeloid Leukemia
Authors: Zhou Jianan , Chen Bobin , Li Pei
Published: August 2021

Objective: Acute myeloid leukemia (AML) is a clonal malignant hematological neoplasm with a poor prognosis and high heterogeneity. Many studies have been conducted on the diagnosis and treatment of AML, but the immune microenvironmental mechanisms underlying AML disease progression have not been fully elucidated. The aim of this study was to find the potential genes in tumor microenvironmental mechanisms underlying the initiation and progression of AML through relevant biological informatics analysis, and investigate the potential influence of the gene in tumor microenvironment (TME).Methods: AML samples of genes were retrieved from The Cancer Genome Atlas (TCGA) databases. The number of tumor-infiltrating immune cells (TIC) as well as immune and stromal components in AML cases was calculated using the ESTIMATE and CIBERSORT algorithms. Two methods, COX regression analysis and protein-protein interaction (PPI) network, were applied to obtain related genes, and the intersection of related genes was taken to obtain differentially expressed genes (DEGs). Gene Set Enrichment Analysis (GSEA) was used for explore the biological signaling pathway. CIBERSORT analysis for the proportion of TICs was performed to reveal that TICs which are related of the target gene.Results: Cross-tabulation analysis of univariate COX regression analysis and PPI network known the β2 integrin factor (ITGB2) as a major predictor of AML prognosis. High expression of ITGB2 was correlated with low survival of AML patients. GSEA revealed that the higher the ITGB2 gene expression, the more active the immune-related activity. CIBERSORT analysis of the TICs ratio revealed that 9 kinds of TICs were negatively correlated with the expression of ITGB2, including CD4 memory resting T cells, CD8 T cells, naive B cells, resting NK cells, Plasma cells, follicular helper T cells, resting Mast cells, Eosinophils and activated mast cells. Only monocytes were positively correlated with ITGB2 expression. These results provided further evidence that ITGB2 levels may determine the prognosis of AML patients by modulating the immune status of TME, which provides an additional suggestion for the treatment of AML.
A Comparison of The Clinical Characteristics Comprising Abdominal Wall Endometriosis of Various Types
Authors: Wu YuShi , Dai Yi , Zhang Junji , Li Xiaoyan , Shi Jinghua , Gu Zhiyue , Zhang Jing , Leng Jinhua
Published: August 2021

Purpose

To classify abdominal wall endometriosis (AWE) according to the invasive levels of tissue mass, and to compare the differences in clinical characteristics between different types of AWE.
Methods

In this study, we retrospectively analyzed the clinical data of 367 patients who had undergone resection of abdominal-wall endometriotic lesions at the Peking Union Medical College Hospital from January 2008 to December 2018, and we divided the patients into three types according to their deepest level of lesion invasion. Type I designated invasion of skin and subcutaneous tissue; type II, of fascia and rectus abdominis; and type III, of peritoneum. We classified, compared, and analyzed the general conditions, clinical manifestations, auxiliary examinations, surgical conditions, postoperative conditions, and recurrence status of patients.
Result

s Of the 367 patients, type I patients accounted for 13.62%, type II patients for 56.68%, and type III for 29.7%. With respect to group comparisons, we observed that as the location of the mass deepened, the rate of concurrent pelvic endometriosis increased (P = 0.007), recurrent AWE was augmented (P = 0.02), the size of the mass increased (P < 0.001), the rate of multiple lesions became elevated (P < 0.001), the rate of mesh implantation increased (P < 0.001), the length of postoperative hospital stay (P < 0.001) was lengthened, the number of postoperative fever cases (P = 0.006) increased, and the risk of drainage placement (P < 0.001) was enhanced. The 5-year cumulative recurrence rate was 3.3%, and there was no significant difference in the recurrence rate among various types of AWE.
Conclusion

Various types of AWE manifest different clinical characteristics, surgical options, associations with pelvic endometriosis, and postoperative conditions.
Burnout and Job Stress of Anaesthesiologists in The Tertiary-Class A Hospital Northwest China: A Questionnaire Survey
Authors: Yang Guang , Fu Xiaoli , He Miao , Qing Zhong , Dong Buhuai , Ye Jiumin
Published: August 2021

Background

Our purpose was to assess job stress and burnout among anaesthesiologists in The Tertiary-class A Hospital Northwest China.
Objectives

Analyzes the possible causes and adverse consequences of increased job stress and burnout of anaesthesiologists in this region and puts forward suggestions in combination with the current national policies.
Study Design:
Questionnaire survey.
Setting:

Data were collected in the Northwest China from February 2020 until April 2020.
Methods

We sent electronic questionnaires to all 1960–2017 practising anaesthesiologists of The Tertiary-class A Hospital Northwest China. Of those, 338 (67.6%) were returned and could be used for analysis. Burnout and job stress were assessed by using modified Maslach Burnout Inventory-Human Services Survey and Chinese Perceived Stress Scale, respectively.
Results

First, as for emotional exhaustion, the situations of anaesthesiologists with different working years and workload are different with statistical significance (P < 0.05); Second, as for depersonalization, the situations of anaesthesiologists with different age, professional title, working years, physical health status and workload are different(P < 0.05); Third, as for personal accomplishment, the situations of anaesthesiologists with different physical health status are different (P < 0.05); Finally, The regression results showed that the longer the fatigue working years and the worse the physical health of anaesthesiologists in Northwest China, the more likely these two factors were to cause burnout (P < 0.05), as for job stress, there was a negative correlation between job stress and physical health status (P < 0.05).
Conclusions

Burnout and high job pressure are common among anaesthesiologists in The Tertiary-class A Hospital in Northwest China. We should focus on the allocation of labor intensity, pay attention to the physical and mental health of employees, establish targeted incentive mechanism, and improve the system of promotion and income rises for grassroots doctors. This may be not only conducive to the quality of medical care for patients, but also conducive to the development of anaesthesiology in China.
Trial Registration:
ChiCTR2000031316. Date registered: Mar 27, 2020.
Gravity cells as a necessary link in string theory. The formula for the gravitational constant, the formula for the mass of the electron, the formula for the minimum distance of the gravitational interaction, the formula for the minimum distance of the Coulomb interaction. The coincidence of the results obtained by the formulas and the experimental data.
Authors: Chernov Andrey
Published: August 2021

In this study, a new concept is introduced into physics - gravitational cells. The gravitational cell hypothesis was organically integrated into string theory. As a result, using the Schwarzschild radius formula and the Coulomb formula, a gravitational formula in the region of black holes was obtained on the basis of two fundamental constants, and its exact value was determined. The value of the "usual" gravitational constant was also confirmed and the mass of the gravitational cell was obtained. The introduction of the gravitational cell hypothesis into string theory made it possible to apply Planck's constant to gravitational interaction. As a result, a formula for the energy of a gravitational quantum and a formula for the vibrational velocity of a gravitational string were obtained. On this basis, the formula for the mass of the electron was obtained and its value was calculated, which coincided with the experimental mass of the electron. According to the formula for the vibrational velocity of the gravitational string, the formula for the minimum distance of the gravitational interaction was obtained and this distance was calculated. This minimum distance of the gravitational interaction with absolute accuracy coincided with the known experimental data obtained when determining the Casimir effect (force). Another great scientific result is the determination by a new formula of the minimum distance of the onset of the action of Coulomb forces between electric charges and obtaining the minimum length of a standing electric wave between charges.
Level of Understanding of Eras Affects Practitioners’ Practice and Perception of Early Postoperative Resumption of Oral Intake: A Nationwide Survey
Authors: Huang Huizhen , Zhang Yuelun , Shen Le , Huang Yuguang
Published: August 2021

Background: Early postoperative resumption of oral intake is supposed to be safe and beneficial to patients recovery. However, practitioners still have great confusion and disagreement about postoperative resumption of oral intake. This is a nationwide survey to investigate the current status of clinical practice and practitioners’ attitude toward postoperative resumption of oral intake along with their level of understanding of the ERAS guidelines.Methods: An anonymous web-based survey questionnaire via mobile social platform was carried out in mainland China from December 11-20, 2020. The Wilcoxon signed rank test or chi-square test was used to compare the propensity of the resumption of oral intake.Results: Totally 5370 responses were received, and 89% of them were from anesthesiology departments. The nature of the responses from clinical practitioners was highly diverse, but each of the three surgery types showed unique patterns of ERAS implementation. The respondents were more conserved regarding the commencement of both fluid and solid diets after gastrointestinal (GI) and hepato-pancreato-biliary (HPB) surgery than after non-abdominal (NA) surgery. Most respondents agreed that early oral intake is beneficial to reduce postoperative complications improve bowel recovery and overall outcome. 55% respondents considered themselves to have a better understanding of ERAS and tended to initiate oral intake early for all three surgery types (P<0.001).Conclusions: The postoperative resumption of oral intake is highly variable among GI, HPB and NA surgeries. A better understanding of ERAS would encourage practitioners to commence oral intake resumption much earlier.
ChemRL-GEM: Geometry Enhanced Molecular Representation Learning for Property Prediction
Authors: Fang Xiaomin , Liu Lihang , Lei Jieqiong , He Donglong , Zhang Shanzhuo , Zhou Jingbo , Wang Fan , Wu Hua , Wang Haifeng
Published: August 2021

Effective molecular representation learning is of great importance to facilitate molecular property prediction, which is a fundamental task for the drug and material industry. Recent advances in graph neural networks (GNNs) have shown great promise in applying GNNs for molecular representation learning. Moreover, a few recent studies have also demonstrated successful applications of self-supervised learning methods to pre-train the GNNs to overcome the problem of insufficient labeled molecules. However, existing GNNs and pre-training strategies usually treat molecules as topological graph data without fully utilizing the molecular geometry information. Whereas, the three-dimensional (3D) spatial structure of a molecule, a.k.a molecular geometry, is one of the most critical factors for determining molecular physical, chemical, and biological properties. To this end, we propose a novel Geometry Enhanced Molecular representation learning method (GEM) for Chemical Representation Learning (ChemRL). At first, we design a geometry-based GNN architecture that simultaneously models atoms, bonds, and bond angles in a molecule. To be specific, we devised double graphs for a molecule: The first one encodes the atom-bond relations; The second one encodes bond-angle relations. Moreover, on top of the devised GNN architecture, we propose several novel geometry-level self-supervised learning strategies to learn spatial knowledge by utilizing the local and global molecular 3D structures. We compare ChemRL-GEM with various state-of-the-art (SOTA) baselines on different molecular benchmarks and exhibit that ChemRL-GEM can significantly outperform all baselines in both regression and classification tasks. For example, the experimental results show an overall improvement of 8.8% on average compared to SOTA baselines on the regression tasks, demonstrating the superiority of the proposed method.
Tract Profiles of The Cerebellar Peduncles In Children Who Stutter
Authors: Johnson Chelsea , Liu Yanni , Waller Noah , Chang Soo-Eun
Published: August 2021

Cerebellar-cortical loops comprise critical neural circuitry that supports self-initiated movements and motor adjustments in response to perceived errors, functions that are affected in stuttering. It is unknown whether structural aspects of cerebellar circuitry are affected in stuttering, in particular in children close to symptom onset. Here we examined white matter diffusivity characteristics of the three cerebellar peduncles (CP) based on diffusion MRI (dMRI) data collected from 41 children who stutter (CWS) and 42 controls in the 3-11 year range. We hypothesized that CWS would exhibit decreased fractional anisotropy (FA) in the right CPs given the contralateral connectivity of the cerebellar-cortical loops and past reports of structural differences in left cortical areas in stuttering speakers. Automatic Fiber Quantification (AFQ) was used to track and segment cerebellar white matter pathways and to extract diffusivity measures. We found significant group differences for FA in the right Inferior CP (ICP) only: controls showed significantly higher FA in the right ventral ICP compared to CWS, controlling for age, sex, and verbal IQ. Furthermore, FA of right ICP was negatively correlated with stuttering frequency in CWS. These results suggest an early developmental difference in the right ICP for CWS compared to age-matched peers, which may indicate an alteration in error processing, a function previously linked to the ICP. Lower FA here may impact error monitoring and sensory input processing to guide motor corrections. Further longitudinal investigations in children may provide additional insights into how CP development links to stuttering persistence and recovery.
Pyrolysis and Combustion Kinetics of Disposable Surgical Face Mask Produced During Covid-19 Pandemic
Authors: Salema Arshad Adam , Zaifullizan Yasmin Mohd , Hong Wong Wai
Published: August 2021

The authors have requested that this preprint be removed from Research Square.
Prevalence of Childhood Adversities Among Inpatients With Mental Disorders: A Cross-Sectional Study At Neuropsychiatric Referral Hospital in Rwanda
Authors: NYIRIMANA Vianney , RUTAKAYILE Bizoza , MUDENGE Charles , MUSAFILI Aimable , CASSADY Cindi , YUBAHWE Janvier
Published: August 2021

Background
The world is dealing with a significant socio-economic burden that must be addressed to secure a favourable future.To figure out this problem, there is an urgent need of healthy and well educated adult population to participate effectively in global economy.Indeed, childhood experiences may affect adult health outcome.Responsive caregiving during childhood is associated with good physical and mental health.On the other hand,a strong link was established between Adverse Childhood Experiences (ACEs) and poor adult physical and mental health outcomes.This study assessed the prevalence of ACEs among adult patients with mental disorders admitted to the post-crisis wards at Caraes Ndera Neuropsychiatric Hospital in Kigali, Rwanda.
Methodology :
This research was developed as a descriptive cross-sectional study that involved a total of 122 patients aged 18 to 64 years.A convenience sampling was used to collect data using the the Adverse Childhood Experiences International Questionnaire (ACE-IQ). Data was analyzed in terms of frequencies and percentages using the Statistical Package for the Social Sciences (SPSS 21.0).
Results
Initially, 159 participants were invited to join the study, 122 (77%) met the inclusion criteria and voluntarily consented to participate. Of the 122 participants, 43.4% were female, 61% were youth, 67.2% had primary school as the highest level of education and 29.5% did not work during the last 12 months. Having separated/divorced or deceased parents was the most frequent ACE item with 64.8% of participants responding affirmatively. Nearly all (98.4%) participants had at least one ACE and 77.9% had at least 4 ACEs.
Conclusions
This study on ACEs in Rwandan adults with mental disorders revealed that 98.4% had at least one ACE and almost 80% of the 122 participants had at least 4 ACEs.The findings indicate that there is a significant need to implement interventions necessary for the prevention of ACEs. Such interventions are necessary to mitigate negative effects of ACEs on child development, to increase children’s resiliency and to improve future adult physical and mental health outcomes.
Association Between Age at Menarche and Metabolic Syndrome in Southwest Iran: A Population-Based Case Control Study
Authors: Cheraghian Bahman , Saki Nader , Rahimi Zahra , Sarvandian Sara , Hashemi Seyed Jalal , kaabi Jamileh , Malehi Amal Saki , Shahriari Arman , Nasehi Nahal
Published: August 2021

Background: Age at menarche (AAM) affects women's health outcomes and could be a risk factor for some diseases such as Metabolic Syndrome (MetS). We assessed the association between age at menarche and metabolic syndrome components (obesity, hypertension, type 2 diabetes and cardiovascular disease) in women aged 35 to 70 years in Hoveyzeh, southwest Iran.Methods: This is a case-control study conducted on 5830 women 35 to 70 years in Hoveyzeh cohort study (HCS), a part of the PERSIAN cohort study, between 2016 to 2018. The case group were women with MetS while the controls were women without MetS. Metabolic syndrome is determined based on standard NCEP-ATP III criteria. Demographic, socioeconomic and reproductive history data were gathered face to face by trained interviews. Also, lab, anthropometrics and blood pressure measurements were assayed for participants. Multiple Logistic Regression was used to estimate the association between age at menarche and metabolic syndrome, with adjustment for potential confounding variables.Results: The overall mean age at menarche was 12.60 ± 1.76 years old. Urban and rural women differed in their age at menarche (at age 12.58±1.71 and 12.63±1.83 years, respectively). Comparison of the four menarche age groups (≤10, 11-12, 13-14, 15-16 years) was statistically different showed between age at menarche and MetS. The odds of having metabolic syndrome for groups with menarche age of 13-14 years and 16-15 years, compared to women with a menstrual age ≤10 years, decreased by 21% and 20%, respectively. Conclusion: The present study showed the effect of age at menarche on odds of having MetS in women 35-70 years.
Utilization of Family Planning And Volunteer Counseling And Testing Service And Associated Factors Among Preparatory School Students In Arba Minch Town, Southern Ethiopia: A Cross- Sectional Study Design
Authors: Mata Melaku , Sisay Gizaw , Girma Meseret , Girma Zeleke , Desalgn Sewitmariam , Wolde Fitsum
Published: August 2021

Background: The utilization of reproductive health service plays important role in preventing youths from different reproductive related health problems. Adolescents in Ethiopia have inadequate access to information and services.Objective: To evaluate utilization of reproductive health service and determinant factors among preparatory school students in Arba Minch town.Method: Institutional based cross sectional study was conducted among randomly selected 541 regular preparatory students in Arba Minch Town. Data was entered and clean into Epidata-4.6 templates then transferred to SPSS-25 statistical software for and analysis. A bi-variable and multivariable logistic regression model was used to identify statistically significant variables of the independent variable. Variables with P-value <0.05, CI 95% in the final model were considered significant determinant variables.Result: Out of those who had sexual intercourse 78.6% and 29.3% of them used family planning and voluntary counseling and testing service respectively. Married adolescents were 4.236 times more likely utilized F/P service than their counterparts (AOR=4.236, 95% CI: 1.182-15.183). The study participants living with both parents were about 1.6 times (AOR=1.645, CI: 1.077-2.513 more likely to use voluntary counseling and testing service compared to those who living with others.Conclusions and Recommendations: Majority (more than three fourth) of adolescents used family planning, but voluntary counseling and testing service utilization were low. The reasons for not utilizing family planning and voluntary counseling and testing service were felt ashamed from friends and unfriendly approach of health workers during service provision. Encourage adolescents open discussion about reproductive health service utilization with different peoples, open discussion within couples and encourage to increase female education are important steps to improve adolescent’s reproductive service utilization.
WITHDRAWN: Valorization of Biomass Pulping Waste As Effective Additive For Enhancing The Performance of Liquid Crystal Hydroxypropyl Cellulose Nanocomposite Film
Authors: Basta Altaf H. , Lotfy Vivian F. , Salem Aya
Published: August 2021

Utilization of wastes from some biomass-based industries in production of nanomaterials is vital in the green chemistry field. This work deals with valorization of lignin from paper making by-product for synthesizing lignin nanoparticles (LNPs) and evaluating its role on performance of hydroxypropyl cellulose (HPC) film as liquid crystal nanocomposite development, in comparison with different carbon nanoallotropes. In this respect LNPs, graphene oxide (GO) and bagasse-based carbon quantum dots (CQD) and carbon oxide (CO) were synthesized and incorporated with HPC during film formation. The effective behavior of LNPs, especially that produced from using highly polar solvent (PEG), on performance of HPC film was evidenced, from examining polarized light microscope together with TEM, SEM, XRD, FTIR, TGA as well as mechanical tests. The results showed that LNPs provided the HPC-nanocomposite film with acceptable thermal stability and mechanical properties, together with distinct complex mixed colorful texture, lines nearly like Grandjean-Cano lines aligned (PO images) and the planar layered morphology.
Strategy Control Model For Sustainable Manufacturing Through Rural Development
Authors: Wu Haishang
Published: August 2021

The authors have requested that this preprint be removed from Research Square.
Influences of Dysphagia on the Prognosis of Chinese Elderly Inpatients: a Prospective Cohort Study
Authors: Meng Zhangmin , Zhou Yulan , Shu Xiao , Yang Zijing , Chen Qian
Published: August 2021

The increasing incidence of dysphagia may pose threats to the health of older patients. The aim of this study was to investigate the adverse influences of dysphagia on the prognosis of older Chinese inpatients. A total of 290 older inpatients with different swallowing functions were involved in this study through group sampling from the geriatric centre of a 3A-level hospital in China. Among them, 125 patients (43.1%) had dysphagia at admission. Based on a cross-sectional investigation, a prospective cohort study was conducted to investigate the incidence of complications, readmission, and death during 6 months of follow-up. A total of 34 patients (11.7%) died, and the remaining 256 patients (88.3%) were investigated concerning their complications. There was a higher prevalence of death among the older patients with dysphagia (15.6% vs 7.9%, RR = 2.361). In terms of complications, older patients with dysphagia were more likely to develop malnutrition (29.8% vs 5.9%, RR = 6.747) and aspiration pneumonia (34.6% vs 11.2%, RR = 4.204). Furthermore, multi-factor analysis demonstrated that dysphagia was an independent predictor of malnutrition and aspiration pneumonia but not an independent predictor of death. In conclusion, dysphagia was proven to be an independent predictor of a poor outcome of Chinese elderly inpatients. Specific clinical management and nursing interventions are recommended to prevent the potential adverse influences of dysphagia.