bluuebunny/crossref_metadata_2025 huggingface dataset:
Neobacillus Paridis sp. nov., an Endophyte of Paris Polyphylla Smith Var. Yunnanensis
Authors: Zhan Peng-Chao , Li Cong-Jian , Zhang Zhen , Mao Rui-Feng , Liu Jing-Ran , Jiang Xing-Wang , Zhi Xiao-Yang , Yang Ling-Ling
Published: September 2021

A novel endophytic strain, designated as YIM B02564T, was isolated from the root of Paris polyphylla Smith var. yunnanensis obtained from Yunnan Province, southwest China. By using a polyphasic approach, cells of the strain were characterized as facultative anaerobic, Gram-positive and rod-shaped. The growth conditions of the strain were found to occur at 20–55 ℃ (optimum, 30 ℃), pH 6.0–9.0 (optimum, pH 7.0). Strain YIM B02564T can tolerate 2% NaCl concentration. Phylogenetic analysis based on 16S rRNA gene sequences revealed that strain YIM B02564T belonged to the genus Neobacillus and the 16S rRNA gene sequence similarity values of strain YIM B02564T to the type strains of members of this genus ranged from 95.6%–97.8%. The DNA G+C content of strain YIM B02564T calculated from the whole genome sequence was 41.6 mol%. Values of the ANI and the dDDH between strain YIM B02564T and its closely related Neobacillus species were below 77.87% and 21.50%. Strain YIM B02564T contained MK-7 as the major menaquinone, iso-C15:0 and anteiso-C15:0 as the major fatty acids. The major polar lipids were diphosphatidylglycerol, phosphatidylglycerol, phosphatidylethanolamine, an unidentified aminophospholipid and four unidentified lipids. It contained meso-diaminopimelic acid in the cell-wall peptidoglycan. On the basis of polyphasic analysis, strain YIM B02564T could be differentiated genotypically and phenotypically from recognized species of the genus Neobacillus. The isolate therefore represents a novel species, for which the name Neobacillus paridis is proposed. The type strain is YIM B02564T (= JCM 34668T = CGMCC 1.18655T).
Seed Priming With an Animal-derived Protein Hydrolysate Improves Drought Tolerance of Tomato Seeds by Enhancing Reserve Mobilization, Osmotic Adjustment, and Antioxidant Mechanism
Authors: Wang Weixuan , Zhang Chenglong , Zheng Wenlong , Lv Haofeng , Zhou Weiwei , Liang Bin , Li Junliang
Published: September 2021

Purpose Protein hydrolysates obtained from agro-industrial byproducts have received much attentions due to their positive roles in regulating plant responses to environmental stresses. However, little is known about the roles of animal protein hydrolysates in mediating seed drought tolerance and the underlying mechanism. Here, the effects of seed priming with pig blood protein hydrolysates (PP) on tomato seed germination and seedling growth under drought stress were investigated. Methods Tomato seeds were soaked with different concentrations of PP solutions for 24 h, and then transferred to filter paper moistened with distilled water or 10% PEG-6000 solution in Petri dish. The germination traits, seeding growth, reserve mobilization, osmolytes, and antioxidant system were determined.Results PP priming effectively alleviated the reduction in seed germination traits, resulting in improved tomato seedling growth under drought stress. PP priming enhanced amylase and sucrose synthase activities, soluble sugar, soluble protein, and free amino acid levels, thereby promoting reserve mobilization in seeds. Moreover, PP priming also reduces osmotic toxicity by increasing the accumulation of proline, soluble protein, and soluble sugar. Drought stress substantially enhanced the production of ROS and subsequent increases in MDA and Evans blue uptake, which were significantly alleviated after PP priming by improving the activities of SOD, POD, and CAT, and non-enzymatic antioxidants. Conclusion PP priming is a feasible method for improving tomato seed germination and seedling growth under drought stress by enhancing reserve mobilization, osmolyte accumulation, and antioxidant systems.
The Performance of BERT as Data Representation of Text Clustering
Authors: Subakti Alvin , Murfi Hendri , Hariadi Nora
Published: September 2021

Text clustering is the task of grouping a set of texts so that text in the same group will be more similar than those from a different group. The process of grouping text manually requires a significant amount of time and labor. Therefore, automation utilizing machine learning is necessary. The standard method used to represent textual data is Term Frequency Inverse Document Frequency (TFIDF). However, TFIDF cannot consider the position and context of a word in a sentence. Bidirectional Encoder Representation from Transformers (BERT) model can produce text representation that incorporates the position and context of a word in a sentence. This research analyzed the performance of the BERT model as data representation for text. Moreover, various feature extraction and normalization methods are also applied for the data representation of the BERT model. To examine the performances of BERT, we use four clustering algorithms, i.e., k-means clustering, eigenspace-based fuzzy c-means, deep embedded clustering, and improved deep embedded clustering. Our simulations show that BERT outperforms the standard TFIDF method in 28 out of 36 metrics. Furthermore, different feature extraction and normalization produced varied performances. The usage of these feature extraction and normalization must be altered depending on the text clustering algorithm used.
Factors Influencing Quality of Life in Patients with Nasopharyngeal Cancer Based on QLICP-NA (Version 2.0)
Authors: Fang Yangchen , Wan Chonghua , Yang Zheng , Wu Jiayuan , Hu Liren , Li Fei , Du Jinlin , Liang Zhangye
Published: September 2021

Objective To determine the quality of life (QoL) of patients with nasopharyngeal carcinoma (NPC) and the clinical factors that influence QoL. Methods Multiple linear regression, simple and canonical correlation analyses were used to analyze the factors that affected QoL in patients with NPC. Results The QoL scores were as follows: physical function domain, 61.03±15.03; mental function domain, 60.95±15.35; social function domain, 59.17±14.16; specific module domain, 75.62±14.87; and total scale score, 66.10±97.18. Multiple linear regression analyses showed that family economic status and clinical stage of the disease are the factors affecting the overall QoL among NPC patients. The simple correlation analysis showed that the hemoglobin level had a positive correlation with physical function, social function, specific module domains, and the total score of the total scale. Canonical correlation analysis revealed a pair of statistically significant typical variables and the canonical correlation coefficient was 0.561 (P<0.05). Conclusion The indicators related to the QoL among patients with NPC included family economic status, clinical stage of the disease, red blood cell count, and albumin, total bilirubin, blood urea nitrogen, creatinine, aspartate aminotransferase, and hemoglobin levels. A focus on these indicators and implementing the corresponding treatment measures had value in improving the QoL among patients with NPC.
The Lymph Node Metastasis Histology in Colorectal Cancer -The Clinical Implication of Tubular-Type Carcinoma in Lymph Nodes -
Authors: Yokoyama Shozo , Watanabe Takashi , Fujita Yoichi , Matsumura Shuichi , Ueda Katsuya , Kinoshita Ikuharu , Murakami Daisuke , Tabata Hirotaka , Tsuji Toshiaki , Ozawa Satoru , Tamaki Takuya , Nakatani Yoshihiro , Oka Masami
Published: September 2021

Cribriform carcinoma in lymph nodes (LNs) is associated with distant metastasis, recurrence, and survival in node-positive colorectal cancer (CRC) patients. However, the clinical significance of lymph node metastasis histology remains to investigate. A total of 318 consecutive CRC patients who underwent a colectomy or anterior resection between January 2011 and June 2016 were enrolled, of whom 119 (37.4 %) had LN metastasis (LNM). Based on the LNM histology, patients with LNM were categorized into four groups: the group with tubular-type in all LNs (tub), with cribriform in at least one LN (cri), with mucinous-type in all LNs (muc), and with poorly differentiated-type carcinoma in at least one LN (por). We investigated the association among these histological types with the survival of these patients. The prognosis was good in order of muc, tub, cri, and por in node-positive CRC patients. Stage II and stage III tub groups did not have significantly different over-all survival times, but not recurrence-free survival times. Multivariate analyses revealed that all tubular-type carcinoma in LNs was independent predictive factor for longer survival times, clinical complete response and possible metastasectomy Diagnosis of lymph node metastatic histology is an important factor for patient stratification in node-positive CRC.
Effect of stress-induced hyperglycemia after non-traumatic non-aneurysmal subarachnoid hemorrhage on clinical complications and functional outcomes
Authors: Zhang Zeyu , Zhao Yue , Liu Yibo , Wang Xiaoyu , Xu Houshi , Fang Yuanjian , Zhang Anke , Lenahan Cameron , Luo Yujie , Chen Sheng
Published: September 2021

Background
Despite having an overall benign course, non-traumatic non-aneurysmal subarachnoid hemorrhage (naSAH) is still accompanied by a risk of clinical complications and poor outcomes. Risk factors and mechanisms of complications and poor outcomes after naSAH remain unknown. Our aim was to explore the effect of stress-induced hyperglycemia (SIH) on complication rates and functional outcomes in naSAH patients.
Methods
We retrospectively reviewed patients with naSAH admitted to our institution between 2013 and 2018. SIH was identified according to previous criterion. Symptomatic vasospasm, delayed cerebral infarction, and hydrocephalus were identified as main complications. Outcomes were reviewed using a modified Rankin Scale (mRS) at discharge, 3 months, and 12 months. A statistical analysis of clinical, radiological, and laboratory risk factors of complications and outcomes was conducted.
Results
244 naSAH patients were incorporated in the cohort with 74 (30.3%) SIH. After adjusting for age, gender, hypertension, Hunt and Hess (HH) grade, modified Fisher Scale (mFS), intraventricular hemorrhage (IVH), and subarachnoid blood distribution, SIH was significantly associated with symptomatic vasospasm (P < 0.001, 12.176 [4.904–30.231]), delayed cerebral infarction (P < 0.001, 12.434 [3.850-40.161]), hydrocephalus (P = 0.008, 5.771 [1.570-21.222]), and poor outcome at 12 months (P = 0.006, 5.506 [1.632–18.581]), whereas the correlation between SIH and poor outcome at discharge (P = 0.064, 2.409 [0.951-6.100]) or 3 months (P = 0.110, 2.029 [0.852–4.833]) was not significant. Incorporation of SIH increased the area under curve (AUC) of ROC in the combined model for predicting symptomatic vasospasm (P = 0.002), delayed cerebral infarction (P = 0.024), hydrocephalus (P = 0.037), and 12-month poor outcome (P = 0.087).
Conclusions
SIH is a significant and independent risk factor for symptomatic vasospasm, delayed cerebral infarction, hydrocephalus, and long-term poor outcome in naSAH patients. Identifying SIH early after naSAH is important for decision-making and treatment planning.
Nonlinear System Identification in coherence with Nonlinearity measure for Dynamic Physical systems- Case Studies
Authors: Xavier Joanofarc , Panda Rames C , Patnaik SK
Published: September 2021

With the recent success of using the time series to vast applications, one would expect its boundless adaptation to problems like nonlinear control and nonlinearity quantification. Though there exist many system identification methods, finding suitable method for identifying a given process is still cryptic. Moreover, to this notch, research on their usage to nonlinear system identification and classification of nonlinearity remains limited. This article hovers around the central idea of developing a ‘kSINDYc’ (key term based Sparse Identification of Nonlinear Dynamics with control) algorithm to capture the nonlinear dynamics of typical physical systems. Furthermore, existing two reliable identification methods namely NL2SQ (Nonlinear least square method) and N3ARX (Neural network based nonlinear auto regressive exogenous input scheme) are also considered for all the physical process-case studies. The primary spotlight of present research is to encapsulate the nonlinear dynamics identified for any process with its nonlinearity level through a mathematical measurement tool. The nonlinear metric Convergence Area based Nonlinear Measure (CANM) calculates the process nonlinearity in the dynamic physical systems and classifies them under mild, medium and highly nonlinear categories. Simulation studies are carried-out on five industrial systems with divergent nonlinear dynamics. The user can make a flawless choice of specific identification methods suitable for given process by finding the nonlinear metric (Δ0). Finally, parametric sensitivity on the measurement has been studied on CSTR and Bioreactor to evaluate the efficacy of kSINDYc on system identification.
Fully automated quantification of cardiac chamber and function assessment in 2-D Echocardiography: clinical feasibility of deep learning-based algorithms
Authors: Kim Sekeun , Park Hyung-Bok , Jeon Jaeik , Arsanjani Reza , Heo Ran , Lee Sang-Eun , Moon Inki , Yoo Sun Kook , Chang Hyuk-Jae
Published: September 2021

Objectives: We aimed to compare the segmentation performance of the current prominent deep learning (DL) algorithms with ground-truth segmentations and to validate the reproducibility of the manually created 2D echocardiographic four cardiac chamber ground-truth annotation.Background: Recently emerged DL based fully-automated chamber segmentation and function assessment methods have shown great potential for future application in aiding image acquisition, quantification, and suggestion for diagnosis. However, the performance of current DL algorithms have not previously been compared with each other. In addition, the reproducibility of ground-truth annotations which are the basis of these algorithms have not yet been fully validated.Methods: We retrospectively enrolled 500 consecutive patients who underwent transthoracic echocardiogram (TTE) from December 2019 to December 2020. Simple U-net, Res-U-net, and Dense-U-net algorithms were compared for the segmentation performances and clinical indices such as left atrial volume (LAV), left ventricular end diastolic volume (LVEDV), LV end systolic volume (LVESV), LV mass, and ejection fraction (EF) were evaluated. The inter- and intra- observer variability analysis was performed by two expert sonographers for a randomly selected echocardiographic view in 100 patients (apical 2-chamber, apical 4-chamber, and parasternal short axis views).Results: The overall performance of all DL methods was excellent (average Dice similarity coefficient (DSC) 0.91 to 0.95 and average Intersection over union (IOU) 0.83 to 0.90), with the exception of LV wall area on PSAX view (average DSC of 0.83, IOU 0.72). In addition, there were no significant difference in clinical indices between ground truth and automated DL measurements. For inter- and intra observer variability analysis, the overall intra observer reproducibility was excellent: LAV (ICC = 0.995), LVEDV (ICC = 0.996), LVESV (ICC = 0.997), LV mass (ICC = 0.991) and EF (ICC = 0.984). The inter-observer reproducibility was slightly lower as compared to intraobserver agreement: LAV (ICC = 0.976), LVEDV (ICC = 0.982), LVESV (ICC =0.970), LV mass (ICC = 0.971), and EF (ICC = 0.899).Conclusions: The three current prominent DL-based fully automated methods are able to reliably perform four-chamber segmentation and quantification of clinical indices. Furthermore, we were able to validate the four cardiac chamber ground-truth annotation and demonstrate an overall excellent reproducibility, but still with some degree of inter-observer variability.
Brain network topology and personality traits: a source level magnetoencephalographic study
Authors: Lopez Emahnuel Troisi , Colonnello Valentina , Liparoti Marianna , Castaldi Mauro , Russo Paolo Maria , Sorrentino Giuseppe , Lucidi Fabio , MANDOLESI Laura
Published: September 2021

Personality neuroscience is focusing on the correlation between individual differences and the efficiency of large-scale networks from the perspective of the brain as an interconnected network. A suitable technique to explore this relationship is the magnetoencephalography (MEG), but little are MEG studies aimed at investigating topological properties correlated to personality traits. By using MEG, the present study is aimed at evaluating how individual differences described in Cloninger’s psychobiological model are correlated with specific cerebral structures. Fifty healthy individuals (20 males, 30 females, mean age: 27.4 ± 4.8 years) underwent Temperament and Character Inventory examination and MEG recording during a resting state condition. High harm avoidance scores were associated with a reduced centrality of the left caudate nucleus and this negative correlation was maintained in females when we analyzed gender differences. Our data suggest that the caudate nucleus plays a key role in adaptive behavior and could be a critical node in insular salience network. The clear difference between males and females allows us to suggest that topological organization correlated to personality is highly dependent on gender. Our findings provide new insights to evaluate the mutual influences of topological and functional connectivity in neural communication efficiency and disruption as biomarkers of psychopathological traits.
Changes in adverse maternal, pregnancy, and delivery outcomes among U.S. delivery hospitalizations during the COVID-19 Pandemic, 2019-2020
Authors: Simeone Regina M. , Downing Karrie F. , Wallace Bailey , Galang Romeo R. , DeSisto Carla L. , Tong Van T. , Zapata Lauren B. , Ko Jean Y. , Ellington Sascha R.
Published: September 2021

Background

Early reports suggested changes in select pregnancy outcomes during the coronavirus disease 2019 (COVID-19) pandemic. The population-level impact of the pandemic on pregnancy and delivery outcomes is not well understood.
Objective

To assess whether pregnancies that ended during the pandemic were at increased or decreased risk of selected adverse outcomes compared to the previous year.
Methods

Data from a cohort of delivery hospitalizations occurring during April-December of 2019 and 2020 in the Premier Healthcare Database were analyzed. Prevalence of select adverse outcomes were examined. Adjusted prevalence ratios (aPR) and 95% confidence intervals (CI) were estimated using Poisson regression with robust standard errors.
Results

We identified 663,620 deliveries occurring April-December of 2019 and 614,093 deliveries occurring April-December of 2020. We observed an increase in in-hospital death from 2019 to 2020 (n=33; 5 per 100,000 vs. n=53; 9 per 100,000, aPR: 1.68, CI: 1.09, 2.59), which was no longer statistically significant after excluding deliveries with a COVID-19 diagnosis (aPR: 1.25, CI: 0.78, 2.00). Intensive care unit admission decreased from 2019 to 2020 (n=10,964; 1.7% vs. n=9,480; 1.5%, aPR: 0.90, CI: 0.87, 0.92). Preterm birth decreased from 2019 to 2020 (n=61,101; 9.2% vs. n=56,158; 9.1%, aPR: 0.96, CI: 0.95, 0.97). The prevalence of cesarean deliveries was similar in 2019 and 2020 (30.9% vs 31.6%, respectively), but there were some differences in cesarean delivery characteristics (e.g., an increase in cesarean deliveries due to conduct of labor [n=2,553; 1.2% vs. n=2,642; 1.4%, aPR: 1.11, CI: 1.05, 1.17]) from 2019 to 2020.
Conclusions

In 2020 compared to 2019, in-hospital deaths among pregnant women increased and there was a small decrease in prevalence of preterm births. The full impact of the COVID-19 pandemic on maternal and pregnancy outcomes remains to be understood. However, it appears that most outcomes investigated experienced minimal change from 2019 to 2020.
“Next Generation Sequencing“ – basierende genomische Biomarker zur Risikodetektion von chronischem Schmerz
Authors:   , Kringel Dario
Published: September 2021

Die Physiologie des Schmerzes umfasst komplexe immunologische, sensorische und inflammatorische Prozesse im Rückenmark, im Gehirn und in der Peripherie. Wiederholte nozizeptive Stimulation induziert pathophysiologische Veränderungen bei der Schmerzweiterleitung, aus denen eine periphere oder zentrale Sensibilisierung resultiert. Diese kann bei dafür anfälligen Patienten zu der Ausbildung von chronischen Schmerzzuständen führen. Obwohl das Wissen über die genauen molekularen Vorgänge der Schmerz-Chronifizierung noch immer unvollständig ist, sind die Identifizierung von Risikofaktoren vernünftige Schritte, um die individuelle Anfälligkeit für die Entwicklung chronischer Schmerzen zu bestimmen. Das Hauptziel dieser Doktorarbeit bestand daher in der Identifikation humaner genetischer Biomarker für chronische Schmerzzustände.
Investigation of User Data Security for Android-based «Signal» Messenger
Authors:   Kuban State Technological University (KubSTU), Kucher V. A. , Putyato M. M. ,   Kuban State Technological University (KubSTU), Makaryan A. S. ,   Kuban State Technological University (KubSTU), Karmanov M. A. ,   Kuban State Technological University (KubSTU)
Published: September 2021

The article presents the security analysis of locally stored enduser data, as well as the specifics of working with them in the application called “Signal” based on Android OS. The investigated version 5.3.12 was the most recent one up to the time of writing this article. According to a certain scenario, test user data was generated in the application, and then the sources information with critical data was extracted from this data. Using the open-source code available, the mechanisms of the application's operation, including the implementation of protection measures, wit the specified critical data were identified and analyzed. A qualitative assessment of implementing protection mechanisms for locally stored critical data was made to distinguish the data with typical protection measures inherent for any mobile applications, and the one specific for applications of this particular class of messengers. As a result, the flaws were discovered related to the inaccessibility of certain protective mechanisms on specific versions of the Android operating system, which could compromise the user data. As an advantage of the messenger protection, the database encryption module could be specified, which provides strong protection against unauthorized access to information due to the lack of a specific version of the assembly for personal computers. This article also proposes an approach to decrypt messenger databases, which requires either an emulator of an Android-based device, or a real mobile device with a specially developed application
Synthesis of Regulators of the Drying Plant Control System Based on Statistical Data
Authors:   National Research Tomsk Polytechnic University (NI TPU), Nguyen V. V. , Shilin A. A. ,   National Research Tomsk Polytechnic University (NI TPU), Bukreev V. G. ,   National Research Tomsk Polytechnic University (NI TPU), Perevoshchikov F. V. ,   National Research Tomsk Polytechnic University (NI TPU), Bryantsev A. A. ,   National Research Tomsk Polytechnic University (NI TPU)
Published: September 2021

In the article a method to carry out a synthesis of regulators of the drying plant control system is considered based on the integration of known statistical data by the Lagrange polynomial. An algorithm to correct the parameters of regulators in problematic modes of operation of the drying plant is proposed. It is shown that the control system developed and implemented on the PLC provides stable control of temperature and humidity during the drying of materials
EXEMPLIFICANDO O USO DO MACRO MAPEAMENTO ELEMENTAR POR XRF (MA-XRF) NA INVESTIGAÇÃO FORENSE DE OBRAS DE ARTE
Authors: Pimenta André , Felix Valter , Silva Daniele , Pereira Marcelo , Oliveira Ana , Ferreira Douglas , Carvalho Cristiano , Silva Fabricio , Gonçalves Elicardo , Dutra Rafael , Pereira Leandro , Pereira Ronaldo , Freitas Renato
Published: September 2021

EXEMPLIFYING THE USE OF MACRO ELEMENTAL MAPPING BY XRF (MA-XRF) SCANNING IN FORENSIC INVESTIGATION OF ARTWORKS. This work exemplifies the potential of employing macro elemental mapping by XRF (MA-XRF) scanning in the forensic investigation of artworks. The results of the investigation of two artworks of different styles and periods are presented and discussed. The images provided by MA-XRF scanning have information about the elemental distribution, which is related to pigments used in the artwork. These images bring different information such as: if there are underlying paintings; if a given pigment was used for the purpose of restoration or in the creation. Therefore, through the images, it is possible to obtain information, which refers to the process of creating the artwork and the history of conservation and restoration. Through the results, it was possible to verify that the two artworks are probably false because they present anachronistic pigments with the supposed period of creation. The analyzes were performed using a portable MA-XRF scanning system, and in addition to presenting the utility of the instrument in these investigations, the work also presents possibilities to explore the MA-XRF data through multivariate statistical analysis and image correlation.
PREDICTIVE MODEL FOR DETERMINING THE MASS OF BHA AND BHT TO BE ADDED IN COMMERCIAL BIODIESEL
Authors: Savada Felipe , Silva Hagata , Mantovani Ana , Chendynskic Letícia , Angilelli Karina , Borsato Dionísio
Published: September 2021

Biodiesel is a biofuel produced by the esterification reaction. It is an option to replace fossil fuels, mainly diesel, due to its similar physical and chemical properties. In this research, a mathematical modeling was performed to predict the antioxidant mass to be added in a commercial biodiesel to achieve the minimum oxidative stability provided by the legislation. An equation for each additive was proposed, with the mass of these antioxidants considered as dependent variables and the conformity parameters as independent ones, obtaining multiple regression equations without intercept. The BHA and BHT antioxidants were used. The equations provided were lower at the 5% level and presented determination coefficients (R²) equal to 0.9790 and 0.9770 for the BHA and BHT, respectively, proving their predictability ability and also showing that they can be used to estimate the antioxidant mass to be added in a biodiesel to reach the current regulations.
EDULCORANTES DE ALTA INTENSIDADE: TENDÊNCIAS DE USO EM ALIMENTOS E AVANÇOS EM TÉCNICAS ANALÍTICAS
Authors: Nicoluci Ícaro , Takehara Carolina , Bragotto Adriana
Published: September 2021

HIGH-INTENSITY SWEETENERS: TRENDS OF USE IN FOODS AND ADVANCES IN ANALYTICAL TECHNIQUES. The high consumption of sugar by the population and its correlation with the increase in the rates of obesity and chronic non-communicable diseases have promoted discussions of strategies to reduce the intake of this ingredient. In addition to consumer campaigns and governmental public policies, the use of high-intensity sweeteners to replace sugar in foods could be a feasible alternative for reducing sugar intake. However, it is important that high-intensity sweeteners be used considering the maximum permitted levels and approved food categories according to the current legislation. In this context, the development and application of analytical methods to determine high-intensity sweeteners in foods is a current and relevant issue. This manuscript aims to review the general aspects and available analytical techniques for the determination of these additives in food matrices.
Protección anticorrosiva de un convertidor de óxido natural (Mimosa tenuiflora) aplicado sobre productos de corrosión de un acero AISI 1018
Authors: Arceo-Gómez David Enrique , Reyes Trujeque Javier , Galván Martínez Ricardo , Orozco Cruz Ricardo
Published: September 2021

Un recubrimiento primario es aquel que es aplicado sobre la superficie de los aceros, como una primera capa de recubrimiento que permite mejorar la adherencia y el sellado de los sistemas protectores. Sin embargo, algunos de sus componentes son tóxicos para el ambiente y dañinos para la salud. Una alternativa amigable con el ambiente es el empleo de convertidores de óxido, obtenidos a partir de extractos naturales de plantas. Su uso puede llegar a tener un fuerte impacto en el ámbito industrial y resultan prometedores en la conservación del patrimonio cultural metálico. En este trabajo, se evaluó el efecto anticorrosivo de un convertidor de óxido obtenido a partir de un extracto de la planta Mimosa tenuiflora, aplicado sobre productos de corrosión de un acero 1018. La caracterización morfológica del convertidor de óxido se llevó a cabo por Microscopía Electrónica de Barrido (MEB). Por su parte, las propiedades anticorrosivas se evaluaron por Espectroscopía de Impedancia Electroquímica (EIE).
Método: Se utilizaron sustratos de acero AISI 1018 y se le aplicaron dos tratamientos de limpieza superficial: decapado químico y chorro de arena. Posteriormente, para formar productos de corrosión, las probetas se expusieron 90 días a la atmósfera urbano-marina de la ciudad de Boca del Río, Veracruz. El extracto utilizado como convertidor de óxido se obtuvo de la planta Mimosa tenuiflora y fueron preparadas dos formulaciones que se aplicaron por aspersión sobre la capa de productos de corrosión. Los productos de corrosión fueron caracterizados por Espectroscopía Raman, Difracción de Rayos X (DRX) y MEB-EDX. Por su parte, la morfología de la película convertida fue caracterizada por MEB. Las propiedades anticorrosivas de los productos de corrosión y el convertidor de óxido fueron evaluadas por EIE durante 24 horas de exposición en una solución de NaCl al 3.5 % en peso.  
Resultados: La capa de productos de corrosión está formada principalmente por goethita, lepidocrocita y hematita. Mediante MEB se observaron cambios en las características morfológicas de los productos de corrosión, los cuales cambian su aspecto superficial rugoso y poroso al de una superficie compacta y craquelada por acción del convertidor de óxido. Los resultados por  EIE, mostraron que el tratamiento por chorro de arena sobre las probetas permitió una mejor adherencia de los productos de corrosión y convertidor de óxido, propiciando un aumento en la capacidad protectora en comparación con el tratamiento superficial por decapado químico.
Discusión o Conclusión: El convertidor de óxido natural mejora las propiedades protectoras de la capa de productos de corrosión. Aunado a lo anterior, una preparación superficial del sustrato con chorro de arena permitió mejorar la adherencia del convertidor de óxido. Este convertidor de óxido puede ser utilizado en el ámbito industrial y el patrimonio cultural metálico.
Urban flood risk analysis of buildings using HEC-RAS 2D in climate change framework
Authors: Madhuri R. , Raja Y. S. L. Sarath , Raju K. Srinivasa , Punith Bonagiri Sai , Manoj Kondisetti
Published: September 2021

The present study aims to assess flood depth, building risk analysis, and the effectiveness of various flood adaptation strategies to attenuate building risk caused by urban floods in climate change scenarios. A framework is proposed where a hydraulic model, Hydrologic Engineering Center's-River Analysis System 2D (HEC-RAS 2D), is applied for 2-dimensional flood modeling to estimate (a) submerged areas, (b) flood depth, and (c) building risk for extreme events corresponding to two representative concentration pathways (RCPs), 6.0 and 8.5. Greater Hyderabad Municipal Corporation (GHMC), India, is chosen for demonstration. Percentages of buildings in GHMC under high, medium, and low risks for RCP 6.0 are 38.19, 9.91, and 51.9% in the respective order, and these are 40.82, 10.55, and 48.63% for RCP 8.5. Six flood proofing (FP) strategies (S1–S6) are proposed for attenuating building risk along with the required capital cost. The capital investment required for FP to achieve the ideal situation of no risk for all buildings (strategy S6) works out to Rs. 3,740 × 107 and Rs. 3,800 × 107 for RCPs 6.0 and 8.5. It is observed that the effect of adaptation strategies is significant.
Study on the driven mechanism of hydrologic drought based on the lithology-combined structure of the Karst drainage basin in South China
Authors: He Zhonghua , Liang Hong , Yang Zhaohui
Published: September 2021

Hydrologic drought, considered as a typical natural phenomenon in the background of global climate changes, is the continuation and development of meteorological and agricultural droughts, and is the ultimate and most thoroughly drought. The research area controlled by the 55 hydrological sections in South China is selected in this paper, and the intensity and frequency of hydrologic droughts are analyzed by the Standardized Runoff Index (SRI), and the driven mechanism of watershed lithologies to hydrologic droughts is discussed. The results show that (i) the hydrological drought of Karst drainage basins is shown the gradual aggravation from the west to east parts in South China, with the significant north–south stripe distributions at the SRI_3 and SRI_6; (ii) the occurring probability of hydrological droughts is the Limestone-type Karst Basin (II and III, 0.17) < Dolomite-type Karst Basin (I and IV, 0.22) < Non-Karst Basin (V, 0.25) in terms of combination types of basin lithologies, and (iii) the Karst Basin (I and III, 0.18) < Semi-Karst Basin (II and IV, 0.2) < Non-Karst Basin (V, 0.25) in terms of basin lithologies. Therefore, this proves that the most water-stored spaces are found in Karst Basins under the differential dissolution or erosion effects of soluble water, followed by in the Semi-Karst Basin, the least water-stored spaces in the Non-Karst Basin.
Ultrastructure of the adrenal gland of paca (Cuniculus paca, Linnaeus, 1766) in captivity
Authors: Garcia Filho Sérgio Pinter , Martins Leandro Luis , Marcusso Paulo Fernandes , Sasahara Tais Harumi de Castro , Machado Márcia Rita Fernandes
Published: September 2021

Lowland paca (Cuniculus paca, Linnaeus, 1766) is a medium-sized rodent that belongs to the Brazilian fauna. Yet little information on its morphology is found in the specialized literature. Thus, the objective of the work was to study the morphology of the adrenal gland of paca by means of microscopic ultrastructure analysis. The adrenal gland secretes specialized substances in the body which promote biological functions of great importance and will provide valuable information to studies in comparative anatomy. Two (2) adult lowland pacas were used, male and female. Soon after death, the animals were positioned in the supine position; their abdominal cavities were opened by pre-retro umbilical and lateral incision followed by folding of the abdominal walls to expose the glands. The adrenal glands were removed; fragments were collected, fixed and prepared for ultrastructure observations using scanning electron microscopy and transmission electron microscopy techniques. It was observed that the adrenal glands of the paca have divisions as well as the limits of the cortical and medullary region, as well as the subdivisions of the glomerulosa, fasciculated and reticulated areas of the cortical region as in other rodents. An ultrastructure of cells and their components also showed a lot of similarity to that already demonstrated in different rodents.
Prevalence of dermatopathies in dogs and cats in the highland of Santa Catarina State, Brazil
Authors: Silvestre Giovanna Sperandio , Gütschow Maria Eduarda Ronzani Pereira , Meira Julia , Custódio Clara de Souza , Motheo Tathiana Ferguson , Pereira Marcy Lancia
Published: September 2021

This was the first study of the prevalence of skin diseases in dogs and cats in Santa Catarina. Medical records of all canine and feline patients referred to the Veterinary Clinic of the Federal University of Santa Catarina (UFSC), Curitibanos campus, were evaluated. From 2015 to 2019, 322 dogs and cats presented dermatological lesions, corresponding to 25.3% of dermatological cases. Among them, 276 (85.7%) were dogs, and 46 (14.3%) were cats. Definitive diagnose were obtained in 72.5% and 71.3% of canine and feline patients, respectively. Mixed breed adults were most likely to develop skin diseases. Among the primary conditions, parasitic, fungal, and bacterial diseases were the most prevalent for both species. In dogs, pulicosis, followed by pyoderma and dermatophytosis, were the major diseases encountered. Nevertheless, cats presented higher prevalence of fungal diseases, followed by parasitic and bacterial disorders. Malassezia otitis was the most prevalent, followed by pulicosis and dermatophytosis.
Fungal dermatitis by Scopulariopsis brevicaulisin Guinea pig (Cavia porcellus)
Authors: Gonçalves Guilherme Augusto Marietto , Tonin Alexandre Alberto
Published: September 2021

Fungal dermatitis is classified into superficial, cutaneous and subcutaneous mycoses. However, the incidence of fungal dermatitis in small mammals is relatively low. Among rodents guinea pig the most affected specie, however it usually has an asymptomatic pattern. The present text reports an unusual case of fungal dermatitis in Caviaporcelluscaused by Scopulariopsis brevicaulis. The animal was received with complaint of alteration of coat around the neck, as well as report of incorrect feeding management. During the physical examination the presence of a dry and crusty dermatitis, negative on fluorescence test of wood. Samples of blood, skin, scabs and hair were collected for parasitic and mycological analysis. The hematological evaluation showed only a discrete eosinophilia; no ectoparasites were observed, but it was noticed the presence of Scopulariopsis brevicaulis. The animal underwent terbinafine and griseofulvin protocol, with total regression of the lesions after 30 days. S. brevicaulis is an unusual geophilic fungus causing animal mycosis, presenting more pathological reports in human mycoses, thus, representing a zoonotic potential. According to the clinical findings and results obtained from mycology assay, it was diagnosed dermatitis by Scopulariopsis brevicaulis, secondary to nutritional deficiency. The combined use of topical terbinafine with systemic griseofulvin was efficient in the treatment. Finally, it was recommended a dietary correction.
Clomipramine and alprazolam to treat noise phobia in a dog: case report
Authors: Thomas Lettycia Demczuk , Thomas Julyanna Demczuk , Wolfran Luciana , Fukushima Fabiola Bono
Published: September 2021

Behavioral disorders, including noise phobia, have a great impact on small animals internal medicine, impairing their quality of life as well as their life expectancy. The objective of this work is to report the case of a male dog who suffered from noise phobia and panic attacks triggered by thunderstorms and fireworks, and did not respond to previous training and treatment. After clinical and laboratory evaluations, he was treated with 2mg/kg clomipramine twice daily for 90 days associated with 0.06mg/kg alprazolam as needed on those days of intense fear. During the first week of treatment, a significant improvement could already be observed, with reduction in destructive behaviors, which lingered on for up to eight months of follow-up. The treatment stabilized the clinical condition and improved the patient’s quality of life.
Dripping test to assessment the water content in frozen chicken carcases commercialized in Ji-Paraná, Rondônia, Brazil
Authors: Fonseca Camila Regina Souza , Pontuschka Rute Bianchini , Dantas Filho Jerônimo Vieira , Dias Ademilson de Assis , Rosa Bruna Laurindo , Gasparotto Paulo Henrique Gilio
Published: September 2021

The growth in demand for chicken meat is due to the increase in demand for white meat, as they are considered tasty and at an attractive price. Therefore, the search for quality is essential. In Brazil, the water loss due to the melting of the carcasses is controlled by companies and by the Ministry of Agriculture, Livestock and Supply (MAPA) and, frequently, they analyze water loss from the carcasses above the limits required by the legislation. Given the assumption, the aimed of this study was to evaluate the water losses due to thawing in frozen chicken carcasses marketed in the municipality of Ji-Paraná, Rondônia, Brazil. There 25 carcasses of whole frozen chickens were evaluated, from six brands, lots and different establishments, submitted to standardized conditions for the performance of the Dripping test, in order to verify the percentage of water absorbed by the carcasses. It was found that 48% of the samples showed water loss beyond that allowed by the current legislation, which is 6%. When observing that almost half of the evaluated carcasses showed irregularities in relation to the legislation, it is understood that the companies that supply these products should be better inspected, carrying out Dripping test analyzes periodically to reduce or eliminate this type of crime.
A Qualitative Description of Nurses’ Psychological Responses in Caring for COVID-19 Patients: An Indonesian Context
Authors: Ismail Suhartini , Ridlo Muhamad , Rochana Nana
Published: September 2021

Introduction:

COVID-19 is a dangerous, infectious disease that has affected the whole world in the past year. In Indonesia, many nurses were not only infected by the virus but also experienced varying psychological responses in providing treatment and performing their tasks. In other words, they faced the daunting responsibility of fighting the disease while taking care of COVID-19 patients.

Objective:

The study aimed to describe nurses’ psychological responses in caring for COVID-19 patients in Indonesia.

Methods:

This was a qualitative descriptive study involving 13 nurses. Using purposive sampling, the participants were selected from three public hospitals in Semarang, Indonesia. These nurses were assigned to take care of COVID-19 patients in the isolation room. The participants underwent face-to-face interviews, either by video calls or through an online application, using semi-structured and in-depth guidelines. The collected data were analyzed using Ello and Kyngas inductive content analysis.

Results:

During the pandemic, the nurses had the following psychological responses in caring for COVID-19 patients in Indonesia: 1) being constantly stressed in carrying out their duties; 2) having no choice but happy to help patients recover at the same time, and 3) getting closer to God as a form of spiritual relief.

Conclusion:

This study provides fundamental data related to further psychological interventions for nurses who experience psychological problems during the COVID-19 pandemic.
Genetic factors and cancer: diagnosis, prognosis and future perspectives
Authors: Bomfim Fernando Russo Costa do
Published: September 2021

Genetics is specifically responsible for several pathologies or, at the least, it is associated with a wide range of them, either as a primary causal agent (congenital genetic diseases) or secondary, being a factor within several possible for a given disease. One of the most critical genetic concepts is developed from the phenotype, equivalent to the genotype associated with the environment. In other words, for a condition to manifest itself, cancer, for example, we need a genetic alteration within the environment, which somehow influences carcinogenesis from stochastic or induced interactions. Cancer cases are approximately 80% and 90% associated with external causes, and environmental changes are mainly motivated by human actions, habits, and behavior, leading to an increased risk of different types of cancer. These changes lead to the formation of a cycle since man promotes environmental changes, leading to genetic modifications responsible for 10-20% of cancer formation. Although the percentage seems not to be significant, we have, in fact, several genetic mechanisms that will lead to the emergence of the most diverse types of cancer, including polymorphisms, mutations, oxidative stress, oncogenes, and genes that regulate the cell cycle, including apoptosis.
Research integrity in times of pandemic
Authors: Jesus-Silva Seleno Glauber de , Antonio Ana Carolina Peçanha
Published: September 2021

In 1994, Douglas Graham Altman, one of the greatest statisticians of all time, wrote "We need less research, better research, and research done for good reasons". Twenty-seven years ago, Altman pointed out that the system favored unscientific behavior and that "bad science" was easy to publish, highlighting the financial implications of this amount of poorly designed research, with erroneous statistical methods, unrepresentative samples, or fraud. The covid-19 pandemic has once again put clinical research in check. The pressure for urgent responses was unprecedented. Knowledge of the origin of the virus, the transmission dynamics, the pathophysiology of the disease, efficient pharmacological and non-pharmacological measures would be counted in lives - and economies, and in governments.
A femininização do magistério no Ceará
Authors: Pinheiro Barbosa Lia , Pereira Marinho Rocha Mayara Gabrielli
Published: September 2021

O presente artigo apresenta a consolidação da Feminização do Magistério a partir da análise do curso de Pedagogia da Faculdade de Filosofia Dom Aureliano Matos-FAFIDAM, em Limoeiro do Norte, Ceará. O percurso metodológico da pesquisa adentrou à análise dos elementos da formação das mulheres nos primeiros anos de funcionamento da FAFIDAM através dos dados coletados nos documentos oficiais, bem como daqueles obtidos por meio de entrevistas realizadas com mulheres que cursaram o curso de Pedagogia na FAFIDAM entre as décadas de 70, 80 e 90 do século XX. Visamos, ainda, compreender em que contexto sócio-histórico estas mulheres se inseriram no curso de Pedagogia e como a Instituição foi responsável pela consolidação dessa Feminização do Magistério. A análise dos dados indica que a consolidação da Feminização do Magistério no curso de Pedagogia da FAFIDAM se deu por dois fatores em si antagônicos: para umas, a falta de oportunidades de traçar outros caminhos acadêmicos e, para outras, uma “vocação” atrelada ao desejo pessoal, fruto de uma construção familiar e/ou social para o magistério.
O centenário de vida de Maria Yedda Leite Linhares
Authors: Macedo de Faria Lia Ciomar , Vieira da Silva Rosemaria Josefa
Published: September 2021

No artigo em tela, analisamos a gestão da historiadora Maria Yedda Leite Linhares na secretaria municipal de educação do Rio de Janeiro. Escolhida pelo vice-governador Darcy Ribeiro e nomeada no dia seguinte a posse do prefeito Jamil Haddad, em março de 1983, as práticas pedagógicas desenvolvidas durante sua gestão, representaram um processo de ruptura com a política educacional instalada pelos governos anteriores. Nosso estudo assinala as especificidades do período em que administrou a pasta da educação municipal, destacando a formação de sua equipe, a reorganização das diretrizes da alfabetização e as demandas apresentadas pela FAMERJ ao grupo político que comandava o Rio de janeiro, ao qual, Maria Yedda integrava. O recorte teórico e documental ressalta a conjuntura política herdada naquele momento e os sentidos e significados que irão demarcar o pensamento educacional de Darcy Ribeiro e as ações políticas brizolista.
Entre o professorado e a militância política
Authors: Barreto Raylane Andreza Dias Navarro , Nascimento Raquel Barreto
Published: September 2021

Este artigo, ancorado na abordagem da história vista de baixo e baseado, sobretudo, em documentos da Secretaria de Segurança Pública de Pernambuco (Brasil), tem como proposta dar a ver a trajetória de vida da professora primária e presa política Maria Celeste Vidal. Por meio de suas experiências em prol dos trabalhadores rurais foi possível desvelar elementos formativos do ser mulher em que a ação individual se associa ao habitus professoral, a militância política e as redes de relacionamentos nos enfrentamentos às violentas estruturas politica e de gênero da década de 1960.
Palavras-chaves: Ligas camponesas, mulher, militância, Pernambuco, regime civil militar.