bluuebunny/crossref_metadata_2025 huggingface dataset:
DENİZCİLİK SEKTÖRÜNDE İŞ BULMADA SOSYAL MEDYA ARAÇLARININ ROLÜ
Authors: Susoy Mert , Yorulmaz Murat
Published: December 2024

Deniz taşımacılığının temel unsuru olan gemi insanları, uluslararası standartlara uygun eğitimlerle yetiştirilmektedirler, bu süreç zaman, emek ve maliyet gerektirmektedir. Gemi insanlarının yetiştirilmesi, istihdam edilmeleri ve yaptıkları işin başarısındaki rolü göz önüne alındığında, denizcilik sektörünün dünya tedarik zincirinin sürdürülebilirliğinin merkezine oturduğu görülmektedir. Gelişen teknoloji ile kolaylaşan ve pratikleşen iletişim imkanları, insan hayatında önemli değişikliklere evirilmeye yol açmaktadır. Bu değişikliklerden en köklülerini aslında dilimize giren internet, Web 2.0 veya sosyal medya gibi farklı kavramlarda görülmektedir. Dolayısıyla küreselleşen dünyada hızla gelişen teknolojinin en tabii ve kuvvetli çıktılarından olan sosyal medyanın da denizcilik sektöründe istihdam oluşturma alanında kullanılmaması beklenemez. Bu kapsamda çalışmanın amacı, denizcilik sektöründeki iş alanlarını açıklamak ve sektör çalışanlarının iş bulmada tercih ettikleri sosyal medya araçlarını ortaya çıkartmaktır. Araştırmada, nitel araştırma yöntemlerinden olan olgu bilim modeli kullanılmış, veri toplama tekniği olarak görüşme tekniği, verilerin analizinde de betimsel ve içerik analizi teknikleri uygulanmıştır. Araştırmanın amacına yönelik olarak denizcilik sektörünün tersane, gemi ve acente alanlarında çalışan 18 kişiden elde edilen verilerin analizi sonucunda ulaşılmıştır. Anket sonuçlarından elde edilen veriler incelendiğinde tüm katılımcıların sosyal medya kullanıcısı olmaları, sosyal medyanın hayatımızda kapladığı yeri görmemiz açısından dikkate değer bir bulgudur. Nitekim kullanıcıların tamamının sosyal medya kullanımını iş arama süreci içerisinde faydalı bir argüman olarak nitelendirmeleri ve LinkedIn sitesinin bu anlamda yine tüm katılımcılar tarafından kabul görmüş bir iş bulma argümanı olduğu tespit edilmiştir.
Strategi Penanganan Anak Tidak Sekolah (ATS) di Kota Pekalongan
Authors: Puji Astuti Tri
Published: December 2024

Pada awal tahun 2024, Kota Pekalongan menerima data ATS dari Dapodik Kemendikbudristek RI sebanyak 1.739 ATS Lulus dan tidak melanjutkan sekolah/Putus Sekolah. Upaya penanganan ATS telah dilakukan sejak tahun 2021, khususnya pada tahun 2024, Kota Pekalongan menjadi salah satu lokus replikasi praktik baik penanganan ATS yang diselenggarakan oleh Pemerintah Provinsi Jawa Tengah bekerja sama dengan UNICEF Perwakilan Jawa dan Bali. Penelitian ini bertujuan untuk mengetahui strategi yang perlu dilakukan Pemerintah Kota Pekalongan dalam penanganan ATS di Kota Pekalongan agar memperoleh hasil yang optimal. Dengan menggunakan data kuantitatif maupun kualitatif yang bersumber dari data primer dan sekunder, penelitian dilakukan dengan menggunakan analisis SWOT (Strengths, Weaknesses, Opportunities dan Threats) yaitu mengidentifikasi dan mengevaluasi faktor internal maupun eksternal yang mendukung maupun yang tidak mendukung dalam penanganan ATS di Kota Pekalongan. Dari hasil pendataan (verifikasi lapangan) sampai dengan tanggal 31 Agustus 2024 diperoleh 5 (lima) kegiatan terbanyak ATS yaitu sebagai pekerja (53,52%), tidak melakukan kegiatan rutin (38,30%), bermain Handphone (3,56%), mengurus keluarga (1,89%), dan anak jalanan (1,14%). Berdasarkan aspek kausalitas, aspek sosial merupakan aspek yang paling dominan (33,46%), disusul oleh budaya (23,39%), ekonomi (20,67%), dan pelayanan (3,10%). Dari hasil penelitian diperoleh bahwa penanganan ATS perlu mendapatkan perhatian dan dukungan dari seluruh partisipan karena penanganan ATS bukan merupakan tanggung jawab satu Perangkat Daerah melainkan multistakeholder meliputi pemerintah, lembaga pendidikan, lembaga swadaya masyarakat dan masyarakat. Strategi penanganan ATS dilakukan melalui: Penguatan dan pengembangan kebijakan dan regulasi daerah, Penguatan dan pengembangan kelembagaan atau organisasi, Penguatan pendataan dan pengembangan aplikasi, Peningkatan akses dan mutu layanan pendidikan yang merata, dan Penguatan literasi dan kapasitas masyarakat dan aparatur.
EVALUATION OF SALES BEHAVIOR BY CUSTOMERS IN THE CONTEXT OF SELECTED CHARACTERISTICS OF SALESPEOPLE
Authors:   University of Presov, Faculty of Management and Business, Tomková Anna , Ondrijová Ivana ,   University of Presov, Faculty of Management and Business
Published: December 2024

Background: The research focuses on the psychological approach to the evaluation of sales behavior from the customers' perspective. In the context of sales behavior, it is essential to consider the approach of the seller, which is successful when sales are effective.

Aims: The aim of the contribution was to evaluate selected types of sales behavior from the perspective of customers in the context of interpersonal relationships. Methods: The research evaluated sales behavior from the customers' perspective, focusing on four distinct types of sales behavior: manipulative, involved, stressed, and assertive. The study utilized the DOS-Z methodology and the Interpersonal Adjective Scales (IAS). Sample: The research sample consisted of 203 respondents, employees from the public and private spheres. Results: The study found no significant differences in sales behavior perceptions between urban and rural customers, but women rated salespeople as more stressed. Manipulative, assertive, stressed, and engaged behaviors correlated with traits like dominance, warmth, extraversion, and with some negative associations such as assertiveness with arrogance and introversion with engagement. Conclusions: The study concludes that place of residence minimally impacts perceptions of sales behavior, while gender influences stressed behavior. Interpersonal traits significantly shape customer perceptions, emphasizing their role in positive experiences.
INFLUENCES OF PERSONAL CHARACTERISTICS ON TRAVEL MOTIVES OF SLOVAK WOMEN ABROAD
Authors:   University of Presov, Faculty of Management and Business, Melnyk Kateryna , Vašaničová Petra ,   University of Presov, Faculty of Management and Business
Published: December 2024

Background: The sustainability of tourist destinations and tourism businesses relies on identifying markets supporting long-term growth. Success depends on understanding the needs of potential consumers and adapting to trends and shifts in source market conditions. This adaptability is key to ensuring continued development and competitiveness. Aims: This paper aims to find which motives are important to Slovak women when traveling abroad and which characteristics of women cause differences in the perceived importance of motives when traveling abroad. Methods: We use the Mann-Whitney U test and the Kruskal-Wallis test to verify three hypotheses. We consider generation, parental status, and marital status as group characteristics. Sample: The research sample consists of 232 Slovak women. Results: The results showed differences between groups for some motives. Conclusions: The study reveals that age, parental status, and marital status significantly influence women's travel motivations, offering valuable insights for the travel industry to develop tailored, generation-specific, and life-stage-sensitive marketing strategies to enhance the travel experience. Implications: Understanding these differences can help cater to diverse needs, ensuring more personalized and satisfying travel experiences.
Ekofobiyi Aşmak: Doğa Eğitiminde Kalbin Yeri
Authors: Evci Nagihan
Published: December 2024

Bu çalışmada "Ekofobiyi Aşmak: Doğa Eğitiminde Kalbin Yeri" isimli eserin yayın kritiği yapılmıştır.
Yukarı Bak Animasyon Filmi İzleyici Yorumlarının Mimarlık Disiplini Kapsamında İncelenmesi
Authors: Şen Sena , Eyüboğlu Hande , Dinçer Sevde , Topaloğlu Gürkan
Published: December 2024

Sinema ve mimarlık, içinde yer aldıkları sanatsal boyutta birbirine sürekli temas eden ve etkileşimleriyle birbirini besleyen iki disiplindir. Bu etkileşim, günümüzde çeşitli araştırma konularına başlık oluşturarak hem mimarlık hem de sinema için farklı bakış açıları ve tasarım girdilerine dönüşmektedir. Sinema ve mimarlık arasındaki bu etkileşimi animasyon filmleri üzerinden incelemek yeni bakış açıları ve anlamların ortaya çıkmasına olanak sağlamaktadır. Bu çalışma, yönetmenliğini Pete Docter’in yaptığı 2009 yılı yapımı Yukarı Bak bir animasyon filmi üzerinden mimarlık sinema etkileşiminin genel izleyiciler üzerindeki etkisi ve farkındalığını sorgulamayı ve sinemasal kurgu içerisinde mimarlık-kullanıcı-zaman değişimini tartışabilmeyi amaçlamaktadır. Bu amaç doğrultusunda, IMDb resmî web sayfasında filme yönelik eleştirel izleyici yorumları üzerinden mimarlık algısı, bilgisi ve farkındalığı incelenmiştir. Pixar Animasyon Stüdyosu tarafından hazırlanan ve yayınlandığı yıl En İyi Animasyon Filmi Oscar’ı dahil birçok ödül alan Yukarı Bak, mimarlığın fiziksel ve psikolojik unsurlarını vurgulaması, kullanıcı ve mekân çeşitliliğini (kentsel mekân, dış mekân, iç mekân) içinde barındırması ve karakterler ve mekânlar açısından yayınlandığı zamana kadar yapılan en gerçekçi animasyonlardan biri olması sebebi ile örneklem olarak seçilmiştir. Çalışmada analizler, görsel içerik analizleri ve izleyici yorumlarına ilişkin metinsel içerik analizleri olmak üzere iki aşamada gerçekleştirilmiştir. İlk aşamada filmde yer alan mimari unsurlar görsel olarak verilmiş ve içerik olarak analiz edilmiştir. İkinci aşamada, IMDb web sayfasında filmle ilgili yapılan yorumlardan seçilen 30 adet eleştirel izleyici yorumu Attoe’nin betimleyici ve yorumlayıcı eleştiri kapsamında analiz edilmiştir. Betimleyici eleştiri kapsamında analiz edilen yorumlarda kentsel mekândan iç mekâna kadar farklı ölçeklerde mimari kavramların/terimlerin kullanıldığı, ana tema olarak kentsel mekânın ve alt tema olarak Güney Amerika’nın öne çıktığı görülmektedir. Yorumlayıcı eleştiri bağlamında ise ana tema olarak mekânın anlamına ilişkin yorumların, alt tema olarak ise Carl ve Ellie’nin eve yüklediği anlam/mekânsal ilişkilerin öne çıktığı görülmektedir.
DESIGN AND FABRICATION OF UAV FOR DEFENCE APPLICATIONS
Authors:   Assistant Professor  Institute of Aeronautical Engineering Hyderabad, Govardhan Dr. D. , Prasanna Jatagni ,   Aeronautical engineering Institute of Aeronautical Engineering Hyderabad,, keerthan Vuppalapu , Anish Erra
Published: December 2024

Because of their adaptability, affordability, and capacity to carry out a variety of tasks, unmanned aerial vehicles, or UAVs, have become essential components of contemporary defense plans. The design and manufacturing process of a UAV specifically suited for defense applications is presented in this study. Modern technology, lightweight materials, and sophisticated aerodynamics are all included into the UAV's design to guarantee optimum performance and dependability under demanding operating conditions. The fabrication process is also described in length, emphasizing the materials chosen, the manufacturing methods used, and the quality control procedures used to satisfy exacting military requirements. Improved target acquisition, observation, reconnaissance, and other mission capabilities essential to contemporary defense operations are promised by the resulting UAV.

Keywords— UAV, Defence Applications, Design, Fabrication, Aerodynamics, Surveillance, Reconnaissance, Target Acquisition, Components.
IOT-Based Health Monitoring System For Paralysis (Quadriplegic) Patients
Authors:   Assistant Professor Dept. of ECE  Bangalore Institute of Technology  Bangalore, India, Swathi Swathi , Saba T S Mymoon ,   Student, Dept. of ECE  Bangalore Institute of Technology  Bangalore, India, R Meghana , Vindhya M S , Maru Juhi
Published: December 2024

Paralysis, which is defined as the loss of muscle function in certain body parts, presents unique issues in healthcare. This necessitates technological and medicinal advances to improve patients’ quality of life. This project, "IoT-Based Health Monitoring System for Paralysis (Quadriplegic) Patients," aims to improve the quality of life for paralysis patients by creating an easy-to-use, affordable device for their connectivity with caregivers and doctors. The wearable sensors track important health information such as heart rate, body temperature, blood pressure, and movement, sending it to healthcare providers via a cloud platform. This allows for quick responses as needed. The gadget lets patients communicate their needs with simple motions, making it much easier for them to converse despite their physical problems. This system reduces visits to hospitals and enables remote care of the patients, thus contributing to better health and independence for paralysis patients.

Key Words: IoT, Paralysis, Health monitoring, Flex Sensors, ESP32 microcontroller.
A Hybrid Model of Particle Swarm Optimization for Wind Energy and Wind Power Through RNN
Authors:   CSE Department Parul University, Vadodara, India, Kunjumon Nithu , Shukla Yatin Kumar , Vajpayee Dr Amit
Published: December 2024

The increasing demand for sustainable energy sources has led to a great deal of study on optimizing wind energy systems. This study proposes a hybrid model that combines recurrent neural networks (RNN) and particle swarm optimization (PSO) to increase the efficiency of wind power forecasting and energy generation. Using previous data and meteorological conditions, the RNN is used to anticipate wind power output. The RNN's parameters are optimized via the PSO algorithm. The suggested model addresses the variable and irregular character of wind patterns in an effort to maximize energy output and enhance wind power forecasts through the integration of many methodologies. The hybrid model's performance is evaluated using actual wind farm data; the findings demonstrate a significant improvement in forecast accuracy and computing efficiency over traditional methods. This work demonstrates how advanced computational techniques and machine learning models can be used to enhance renewable energy systems and contribute to the development of safer and more effective wind energy solutions.

Keywords - Particle Swarm Optimization, Recurrent Neural Networks, Wind Energy, Wind Power Forecasting, Renewable Energy
Roadside enforcement powers and automated vehicles in the European Union
Authors:   Charles Darwin University, Brady Mark , Tranter Kieran ,   Queensland University of Technology
Published: December 2024

This article reports on a study of the adaptability of European Union (EU) roadside enforcement powers to automated vehicles (AVs). It identifies technological obsolescence within EU laws where there are powers to stop vehicles being directed to the ‘driver’, ‘road users’ or ‘traffic participant’ all of which are assumed to be a ‘human’ controlling a vehicle. This is problematic in an automated transport future where automated driving systems (ADS) will increasingly be in control of the dynamic driving tasks. This article concludes that instead of ‘human-centric’ roadside enforcement powers, lawmakers should move to a ‘vehicle-centric’ focus, where the vehicle (irrespective of who, or what, is driving) should be the addressee of the legal power and provides examples of reform directions.
Adli Sürece Dahil Olan Çocuklara Yönelik Uygulamaların Hak Temelli Yaklaşım Perspektifinden Değerlendirilmesi
Authors: Demirci Ayşe , Kırlıoğlu Mehmet , Atik Edanur
Published: December 2024

Sosyal hizmetin bir insan hakları mesleği olduğu vurgulanmaktadır. Sosyal hizmet insanı, hak sahibi olarak görür ve insanın bu haklara ulaşması noktasında onun savunuculuk rolünü üstlenir. İnsanın değerli ve haklarının önemli olduğu ortaya koyulduğunda sosyal hizmet müdahalesine ihtiyaç duyan kesimlerden biri de şüphesiz çocuklardır. Bu çalışmada çocukların adli sürece hangi rolde ve nasıl dahil olduğu, mağdur, suça sürüklenen, tanık, vasi tayin edilen, evlat edinilen, hakkında velayet davası olan çocuklar ve bu çocuklara yönelik olarak sunulan hizmetlerin çocukların psikososyal iyilik halleri ve hak temelli yaklaşım açısından ele alınmıştır. Çalışmanın ilgili alan yazına katkı sağlayacağı düşünülmüştür.
PENGUJIAN KUAT TEKAN BETON MENGGUNAKAN TULANGAN BAMBU BETUNG ( DENDROCALAMUS ASPER) DENGAN KOMBINASI BATU SUNGAI DAN PASIR GUNUN
Authors: SRI SUSILAWATI  , Lahay Fahrudin , Auliyah Ilmih
Published: December 2024

Beton merupakan bahan bangunan yang umumnya diperkuat dengan tulangan baja sebagai bahan yang dapat bekerja sama dan mampu membantu kelemahannya,  namun dalam penggunaan baja sebagai tulangan sering dijumpai beberapa kelemahan diantaranya cepat panas, berkarat dan resiko terjadinya korosi, selain itu material pembuatan baja tulangan adalah produk olahan hasil tambang yang pada akhirnya akan habis. Untuk itu dibutuhkan material alternatif yang memiliki mutu yang sama dengan baja tulangan, salah satu material yang cukup potensial dalam menggantikan baja tulangan adalah bambu. Penggunaan bambu sebagai material konstruksi selama ini masih bersifat sekunder. Hal ini disebabkan karena masih minimnya pengetahuan masyarakat mengenai sifat-sifat mekanik dan fisik struktur bambu. Bambu yang digunakan adalah bambu jenis betung yang akan dibentuk dengan ukuran tulangan d10, untuk meningkatkan daya rekat bambu terhadap beton, maka akan dilakukan dua perlakuan terhadap bambu yang pertama bambu akan dililit dengan kawat bendrat, kedua bambu akan dipasangkan klem pipa. Dengan menggunakan komposisi campuran mutu beton f’c 18,68 Mpa (K 225) dengan benda uji berupa silinder dengan diameter 15 cm dan tinggi 30 cm. Jumlah sampel yang dibuat yaitu 4 sampel beton tanpa tulangan, 4 sampel beton bertulang bambu yang dililit kawat bendrat dan 4 sampel beton bertulang bambu yang dipasangkan klem pipa. Pengujian dilakukan pada saat umur beton 28 hari. Dari hasil penelitian diperoleh bahwa nilai kuat tekan rata – rata beton normal f’c = 21,42 Mpa = K 258,12 Kg/cm2, beton bertulang bambu yang dililit kawat bendrat 19,94 Mpa = K 240,23 Kg/cm2 dan beton bertulang bambu yang pasangkan klem pipa sebesar f’c 17,25 Mpa = K 207,86 Kg/cm2.
RESORT DIKAWASAN MANGROVE DENGAN PENDEKATAN ARSITEKTUR EKOLOGI (KAB. BANGGAI LAUT)
Authors: Mangundap Poppy , Sumampouw Merlijn Justin , Masulili Jufri Azis
Published: December 2024

Salah satu kebutuhan hidup masyarakat modern saat ini adalah rekreasi. Hal ini dibuktikan dengan meningkatnya jumlah wisatawan setiap tahun, baik wisatawan mancanegara maupun wisatawan nusantara. Peningkatan ini perlu diimbangi dengan peningkatan penyediaan akomodasi untuk mengcover kegiatan para wisatawan, baik wisatawan lokal maupun mancanegara.
Oleh karena itu, perlu adanya wadah atau sarana untuk merilekskan pikiran atau refreshing yang nyaman bagi masyarakat yaitu berupa resort.
Sulawesi Tengah merupakan salah satu Provinsi di Indonesia yang kaya akan potensi alam dan budaya. Salah satunya adalah Kabupaten Banggai Laut yang memiliki potensi beragam mulai dari wisata bahari, situs sejarah, serta keindahan alam lainnya yang dapat menjadi ciri khas dan daya tarik bagi wisatawan untuk berkunjung.
Objek rancangan ini berupa resort yang berada di kawasan hutan mangrove. Oleh karena itu, upaya dalam meminimalisir kerusakan lingkungan salah satunya ialah mendesain bangunan yang ramah lingkungan.
Arsitektur ekologi merupakan pembangunan yang berwawasan lingkungan, dimana memanfaatkan potensi alam semaksimal mungkin. Pendekatan arsitektur ekologi yang diterapkan dalam kawasan adalah pengolahan grey water, penggunaan material lokal dan memaksimalkan area hijau dalam kawasan
İKİ FARKLI SİMÜLASYON PROGRAMI KULLANILARAK OPTİMUM GÜNEŞ PANELİ EĞİM AÇISININ BELİRLENMESİ: AZERBAYCAN ÖRNEĞİ
Authors: İslamov Samir , Onay Özlem
Published: December 2024

Günümüzde nüfus artışı ve teknolojideki gelişmelere bağlı olarak artan enerji talebini karşılamak ve enerjide dışa bağlamlılığını azaltmak için, yeni teknolojiler geliştirerek yenilenebilir enerji kaynaklarının kullanımdaki payını artırmak oldukça önemlidir. Yenilenebilir kaynaklardan en yaygın kullanılmakta olan güneş enerjisi uygun maliyeti ve kolay kurulumu olması nedeniyle daha çok tercih edilmektedir. Ancak gölgeden kaçma, uygun ve kaliteli ekipmanlar, toz ve kirlilikten kaçma gibi diğer etkenler de güneşten optimum şekilde enerji almayı etkilemektedir. Bu nedenle güneş enerjisinden optimum miktarda elektrik elde edilebilmesi için, PV panellerin güneşe optimum bir açıda yerleştirilmesi oldukça önem arz etmektedir. Bu tez kapsamında, güneş enerjisi yatırımları açısından henüz yeni gelişmekte olan Azerbaycan’da yenilenebilir enerji teşviklerinin arttırılması ve kullanımının yaygınlaştırılması amacı ile, 14 farklı siyasi bölge için yıllık değişim süreçlerinde optimum panel eğim açısı ve farklı eğim açılarında PV paneller üzerine gelen radyasyon miktarları hesaplanmış ve elde edilen ışınım miktarları elektrik enerjisine dönüştürülerek PV panellerin kurulumu için en uygun şehir belirlenmiştir.
İNSANSIZ HAVA ARAÇLARI PERVANELERİNİN AKIŞ VE YAPISAL ANALİZ ÇALIŞMASI
Authors: Türk Tayip , Uzun Metin
Published: December 2024

Pervaneli uçaklarda kullanılan motor bıçakları, havacılık endüstrisinde önemli bir rol oynamakta olup, bu bileşenlerin performansını ve dayanıklılığını değerlendirmek adına detaylı analizlere tabi tutulmuştur. Bu analizler, akış ve yapısal özellikleri içermekte olup, Fluent yazılımı kullanılarak gerçekleştirilmiş ve kapsamlı bir rapor ile belgelenmiştir. Akış analizi, pervanedeki hız ve basınç kontürlerini içermekte, ayrıca streamline ve hız vektörleri sonuçlarını detaylı bir şekilde ortaya koymaktadır. Bu veriler, pervanenin aerodinamik performansını anlamak adına kritik öneme sahiptir. Fluent içerisinde yapılan analizlerde ise basınç kuvvetleri, yapısal analizin bir parçası olarak ele alınmıştır. Bu, pervane üzerindeki kuvvetlerin ve etkileşimlerin anlaşılmasına katkı sağlamaktadır.Yapısal analiz kapsamında pervane üzerindeki toplam deformasyon, gerilim ve gerinim analizleri detaylı bir şekilde ele alınmıştır. Bu analizler, malzeme dayanıklılığını, genel yapısal bütünlüğü ve potansiyel zayıf noktaları belirleme açısından büyük öneme sahiptir. Sonuç olarak, bu kapsamlı analizler, pervaneli uçaklarda kullanılan motor bıçaklarının performansını optimize etmek, dayanıklılıklarını artırmak ve güvenilirliklerini sağlamak adına mühendislik çözümlerine yönlendirilmiş bir yaklaşım sunmaktadır. Bu rapor, havacılık endüstrisindeki teknolojik gelişmelere katkıda bulunan önemli bir mühendislik çalışmasıdır
Seed and Pollen Transmission of Tomato Spotted Wilt Orthotospovirus (TSWV) in Pepper
Authors: Uslu Yunus Emre , Yorgancı Sevdiye
Published: December 2024

Tomato spotted wilt orthotospovirus (TSWV) is a harmful pathogen that significantly reduces crop production and quality. TSWV can infect approximately 1,000 plant species in 84 different plant families, such as tomato, pepper, lettuce, tobacco, and various types of wild plants, belonging to the Solanaceae family. TSWV is a member of the Orthotospovirus genus and is an isometric-enveloped particle. TSWV can be transmitted mechanically, seed-borne, and by nine species of thrips belonging to the genera Thrips, Scirtothrips,Frankliniella.
In this study, it was determined that TSWV could be transmitted by seeds, but no transmission by pollen was detected. RT-PCR and visual assessment data demonstrate the seed transmission ability of TSWV in peppers. TSWV was detected in both the seed and seed coat of pepper. Additionally, TSWV was detected in different organs of the pepper plant. TSWV was detected in the endocarp, mesocarp, exocarp, pedicel, and placenta of pepper fruit and sepal, petal, pistil, and stamen of pepper flower. After the germination of infected pepper seeds, TSWV was detected in the cotyledons and true leaves, but no symptoms were observed.
These data provided information about the localization of TSWV in pepper plants and provided further evidence of TSWV seed transmission ability.
Short-term effect of different doses of sewage sludge on soil physical and hydraulic properties with different irrigation regimes in a silage maize field
Authors: Altun Mehmet , Sahin Ustun
Published: December 2024

Soil physical and hydraulic properties may be affected significantly from stabilized sewage sludge, and irrigation regimes may change the magnitude of these effects. Therefore, we examined the effects of different sewage sludge doses (D0: 0 t/ha, D1: 30 t/ha, D2: 60 t/ha, D3: 90 t/ha) and irrigation regimes (S1, S2, S3) on the soil physical and hydraulic properties with two-year study in a silage maize cultivated soil. The experiment was carried out in a completely random factorial design with three replications. In the S1, S2 and S3 irrigation regimes, when the sum of estimated crop evapotranspiration by FAO-Penman-Monteith approach and effective precipitation difference were 25 mm, 50 mm and 75 mm, respectively, irrigations were carried out and the moisture deficit in the soil was completed to field capacity. While moisture regimes did not have significant effects on soil physical and hydraulic properties, sewage sludge doses resulted in significant effects. Compared to D0, 3.1% lower bulk density, 1.9% lower particle density, 14.9% higher wet aggregate stability and 2.6% higher gravimetric field capacity values were determined at the D3 treatment. It was determined that these improvements were due to the high organic matter content of the sewage sludge, which increased the organic matter content in the soil with increasing doses, and it was also supported by significant linear relationships between the organic matter and these parameters. As a conclusion, although the importance of the positive effects of increasing dose can be emphasized, it can be stated that longer-term studies are needed to see more permanent and effective results.
Assessment of InDel Variations in CPT1A and PRDM6 Genes Across Three Anatolian Goat Populations
Authors: Aktaş Yusuf , Atmaca Veli , Demir Eymen , Karslı Taki
Published: December 2024

Identifying candidate genes associated with growth traits in livestock and incorporating them into Marker Assisted Selection (MAS) studies, in addition to classical selection methods, can increase genetic progress and thus profitability. Carnitine Palmitoyl Transferase 1a (CPT1a) and PR domain family 6 (PRDM6) are among the candidate genes reported to be associated with growth traits in goats. This study aimed to identify polymorphisms in the CPT1a and PRDM6 genes related to growth traits in Kıl (HAI), Honamlı (HNM), and Kabakulak (KBK) goats, and to discuss their potential use in MAS studies. The II genotype of the CPT1a gene was not found in the HNM or KIL goats, whereas the KBK population included all three genotypes (II, ID, and DD). The frequency of the ID genotype ranged from 0.25 (HAI) to 0.40 (KBK), while the DD genotype frequency ranged from 0.37 (KBK) to 0.75 (HAI). For the PRDM6 gene, the KBK population was found to be monomorphic, containing only the DD genotype. Although the II genotype was not detected in the HNM and HAI breeds, the ID genotype frequencies were calculated as 0.05 and 0.07, respectively. The study's findings point out that the CPT1a gene can be used in MAS studies for HNM, KBK, and HAI goats, whereas the PRDM6 gene cannot be utilized.
Beneficial Effects on Growth Performance of Brown Shrimp (Penaeus Aztecus) Fed Dietary Inulin and Vitamin C
Authors: Kaya Doğukan , Genç Ercüment
Published: December 2024

This study evaluated the effects of different dietary doses of inulin, vitamin C and combinations on the growth performance of brown shrimp (Penaeus aztecus). The experiment was conducted over a period of 84 days using 27 tanks (20 juvenile shrimp/tank, initial weight: 0.85 g) with a total of 540 individuals. Nine dietary treatments were formulated: I0C0 (control, basal diet); I3C0 (0.3% inulin); I4C0 (0.4% inulin); I0C0.1 (0.1% vitamin C); I0C0.2 (0.2% vitamin C); I3C0.1 (0.3% inulin + 0.1% vitamin C); I4C0.1 (0.4% inulin + 0.1% vitamin C); I3C0.2 (0.3% inulin + 0.2% vitamin C); and I4C0.2 (0.4% inulin + 0.2% vitamin C). Shrimp fed with the I4C0.2 diet exhibited the highest growth performance, achieving the best values for final body weight, weight gain, specific growth rate, protein efficiency ratio, and feed conversion ratio. While the I4C0.2 group showed superior feed efficiency, intermediate improvements were observed in the I3C0.2, I4C0.1, and I0C0.2 groups, which also demonstrated significantly higher performance metrics compared to the control (P < 0.05). These findings highlight the potential of inulin and vitamin C as effective feed additives for improving growth performance in brown shrimp, either individually or in combination. The remarkable synergistic effects observed in the I4C0.2 group suggest that this combination promotes better growth and feed efficiency. Future studies should explore the physiological and molecular mechanisms underlying these effects to optimize the application of inulin and vitamin C as functional feed additives.
Measure of online indices among tertiary institution students in Lagos, Nigeria
Authors: Yekinni Olufunmilola
Published: December 2024

Online indices can serve as a gauge of students' digital readiness and proficiency in navigating digital learning environments. Assessing students' familiarity with digital tools, online communication platforms, and information literacy skills can help institutions tailor support services and training programs to meet students’ needs. Hopefully, it is expected that data generated can inform instructional design and course delivery strategies that would enhance the online learning experience and promote student success. Hence, this research work assesses the extent of undergraduate students’ response to ten online indices such as attendance, attention, regularity, distraction and so on, using an adapted questionnaire. Answers were provided to three research questions raised in the study. Data generated was analysed using descriptive statistics of frequency counts, percentages, mean and Standard deviation. Findings revealed that undergraduate students are ready to navigate digital learning as seen in their engagement in online learning and agreement to convenience in attending online classes among others, though it is established that they face technical issues during online classes. It is therefore recommended that tertiary institutions can leverage on undergraduates digital literacy and accept the change for effective technological integration.
Exploring Seaweed Potential to Induce Cold Resistance in Tomato
Authors: Bashir Muhammad Junaid , Ahmad Tanveer , Khan Muhammad Usman , Saddique Muhammad Abu Bakar , Bokhari Syeda Anum Masood , Tariq Muhammad , Ishtiaq Hamid , Naseer Mudassar , Alvi Abid Mahmood
Published: December 2024

Tomato is a member of the Solanaceae family, one of the most significant vegetable crops worldwide. Tomato fruit is a rich source of vitamins, minerals, dietary fiber and essential amino acids.  Cold stress is an important limiting factor for tomato cultivation, leading to reduced growth, yield and quality. Thus, the purpose of this research was to investigate, how tomato growth, development, productivity and tolerance to abiotic stress specifically, cold stress was improved by seaweed (Ascophyllum nodosum) extract. Various concentration of seaweed extract was given to the tomato plants as T0 (control), T1(5mg/L), T2(10 mg/L), T3(20 mg/L), T4(25 mg/L) and T5 (30 mg/L). This study was carried out to measure the foliar application of seaweed on tomato crop yield during winter season 2023-24. A randomized complete block design (RCBD) was used in this experiment. Results regarding the plant height, number of branches, number of flower, number of fruit per plant, fruit length, fruit diameter and fruit weight. Results showed that the highest plant height LY-36, Pi-7 and Naqeeb followed by LY-47 were observed the T5 (30mg/L). Results showed that the maximum number of flower and fruit Pi-1 followed by Pi-13, Pi-7, Naqeeb and Sahel were observed the T5 (30mg/L). On the other hand, maximum fruit diameter LY-47 followed by CWO-4 were observed T5 (30mg/L). The result showed the maximum fruit weight CWO-4 followed by LY-48 were observed T5 (30mg/L). The findings give a positive correlation between tomato resistance and cold stress. Hence, seaweed extract at the rate of 30 mg/L is recommended for cultivation of tomato under cold conditions.
Sero-Surveillance of Measles Virus Seropositivity Amongst Vaccinated Children of Rural Areas of Sindh, Pakistan
Authors: Hussain Zeb , Fatima Ambreen , Qureshi Muhammad Sameer , Khan Asif Iqbal , Sharafat Shaheen
Published: December 2024

Measles remains a serious public health concern worldwide, and outbreaks persist despite large vaccination campaigns, particularly in low-income areas. This study seeks to contribute to the existing body of information by analyzing antibody levels in vaccinated newborns, determining the durability of protection, and identifying potential vaccination gaps. Understanding the measles seroprevalence in this specific area is critical in order to optimize vaccination strategies and ensure the continuous protection of vulnerable people in rural Sindh, Pakistan. Serum samples were collected from 173 children using standard sample collection protocol. Measles-specific IgG antibodies were quantified using enzyme-linked immune sorbent assay (ELISA) at the Department of Microbiology Dow Diagnostic Research and Reference Laboratory (DDRRL).   The study recruited children with an average age of 41.3 months, evenly split between males (n=88) and females (n=81), all vaccinated as per their parents' records. The measles IgG antibodies seropositivity ratio in children among the vaccinated population was 53 (30.6%), and seronegative 120 (69.4%) out of 173. The study revealed alarming rates of measles susceptibility among vaccinated children in Pakistan, despite analyzing various factors, including demographics and socio-economic status, no significant associations with measles susceptibility were found. These findings emphasize the need for improved vaccination strategies to address deficiencies in immunity levels and mitigate the risk of measles outbreaks in the region.
Evaluation and Sequencing of 16S rRNA Gene for Molecular Identification of Prevalent Salmonella Strains Isolated from Food and Water
Authors: Urooba Jamal  , Ramsha Soomro  , Noor ul Huda  , Fouzia Zeeshan  , Shaista Urooj  , Muhammad Naseem Khan  , Tanveer Abbas  , Zulfiqar Ali Mirani
Published: December 2024

This Study is to identify prevalent strains using 16S rRNA, a standard molecular marker that reveals the phylogenetic. Salmonella contains the virulence gene Invasive-A (Inv-A), which increases the pathogenicity of the relationships between bacterial species. It is identified using PCR, targeted gene sequencing, and phylogenetic grouping. A total of 110 food and water samples collected from Karachi were examined to ascertain the prevalence. 16S rRNA gene is for smaller subunits and its function hasn't altered over time, making it one of the standard genes to identify bacteria and helps it connect to the host's epithelial cells, facilitating the infection. Combining the amplification of these two genes with gene sequencing and phylogenetic analysis can help determine where these species actually originated.16S rRNA and the Inv-A gene were amplified in the positive samples. MEGA-X is used to build a phylogenetic Maximum Likelihood tree while using existing and newly discovered research sequences. The examination of this tree reveals the relative proximity or divergence of other Salmonella species from these isolates as well as the geographic origin of these species.
Evaluation of antioxidant, anti-inflammatory and spasmolytic potential of 3-Benzyloxy-4-Methoxy-β-Phenylethylamide in rats having cyclophosphamide-induced-interstitial cystitis
Authors: Rehman Bisma
Published: December 2024

The urine symptoms signalizing persistent pelvic pain and bladder ailment is known asInterstitial cystitis (IC); with exclusion of recurring infection, cancer, medication or radiation induceddamage (Marcu, Campian, and Tu 2018) . IC is a chronic illness. In its early phases, IC manifests asflare-and-remission cycle; including stress factors, like mental, physical, or hormonal changes, can causeflares (Ha and Xu 2017) . Food and drink can also aggravate the condition, It has been documented in thepast, infectious diseases and immune system were found to be highly elevated in IC with complimentdeposits in the bladder, according to RNA- sequence analysis (Hamsa and Kuttan 2011) . Urinecomponents may seep in sub-urothelial gaps and bladder wall if permeability barrier's components aredamaged. In the bladder biopsies of IC patients, abnormal expression of chondroitin sulphate,uroplakins, and tight proteins junction was found. Along with, ongoing inflammatory stress may causeinfiltrating lymphocytes to colonially expand (Parsons et al. 2012) . There some investigations haveshown that a reduction in cortisol levels is accompanied by an increase in sympathetic tone (Lopez andMangır 2021) . Research indicates that IC affects women more than men, with a 5:1 anticipated ratiobetween the sexes (He et al. 2015) . Patients with IC often complain of anxiety, depression, emotionalstress, insomnia and libido related problems. It is well recognized that IC diminishes the value ofmillions of lives, only in the US (Chung et al. 2019) .
Formulation development of ranitidine with nanoparticles for enhancement of efficacy
Authors: Ahmed Naseer
Published: December 2024

In the current world, various forms of cardiovascular diseases such as hypertension, stroke, heart failure, and arrhythmias— along with other diseases —critically impact a person’s life and overall well-being. It is becoming a global challenge to overcome these diseases (Li 2023). In 2021 the approximate number of patients suffering from cardiovascular diseases globally was 20.5 million and the predicted cardiovascular death rate of any given year over the ensuing hundred years in any country was estimated to be about 1.05% (Oleg Gaidai 2023b). Symptoms of cardiovascular diseases vary from patient to patient (Corrine Y. Jurgens 2022) and can be caused by various factors such as smoking, diet, unhealthy lifestyle, obesity, and diabetes. (Dahlöf 2010, R. Nangia 2016). Coronary artery disease most commonly arises as a result of cholesterol buildup in the coronary artery or due to damage of the arterial lining causing a decrease in blood supply to the heart (Peter Libby 2005, Valentin Fuster 1992).
Escitalopram Use in Depression & the Influence of Genetic Variations on Its Safety & Efficacy
Authors: Zaheer Tahreem , Shahid Fatima , Chhetri Pratima
Published: December 2024

Major depressive disorder (MDD) is a common debilitating mental illness marked by sad feelings, depressed mood, and lack of interest in routine chores that persists daily or for a minimum of two weeks.  Serotonin-norepinephrine inhibitors, selective serotonin reuptake inhibitors, tricyclic antidepressants, monoamine oxidase inhibitors, and atypical antidepressants are some of the common classes of drugs used for the treatment of MDD. Despite strenuous efforts by the researchers, hardly any new antidepressant agent has entered the market. Escitalopram, a highly selective serotonin reuptake inhibitor, is the drug of choice for the treatment of MDD. However, although escitalopram is one of the most frequently prescribed antidepressant agents, a large percentage of MDD patients show variable remission and response to escitalopram.  Scientists spent decades finding the underlying mechanism responsible for the significant variations in drug response and incidence of adverse effects. These inter-individual variations in therapeutic response serve as a foundation for the inception of the pharmacogenomic. Pharmacogenomics is a field of research that expounds on the impact of gene variation on altered clinical outcomes of drugs. There has been substantial hope and potential that pharmacogenomics will ameliorate the current therapies for MDD and aid in finding novel targets for new drug discoveries. Currently, numerous candidate genes have been identified, implicated in changing drug response, whether at the receptor, transporter, or drug-metabolizing enzyme. In this review, we attempt to compile the studies on the genetic variations that have been found to be associated with escitalopram efficacy and adverse effects and briefly discuss the pathophysiology and currently available treatment options for MDD
Genetic variations in CYP2B6 and CYP2C19 genes and their effects on antidepressant actions and adverse effects of sertraline in patients with majordepressive disorder
Authors: Siraj Fatima
Published: December 2024

BACKGROUND: Selective serotonin reuptake inhibitor (SSRI), sertraline, is one of the most frequently prescribed antidepressants used to treat Major Depressive Disorder (MDD) and utilized as the first-line treatment for depression. Sertraline is primarily metabolized by CYP2B6 and CYP2C19, which are identified as highly polymorphic. Genetic variation in CYP2C19 and CYP2B6 results in altered enzymatic activity, ultimately resulting in interindividual differences in the sertraline therapeutic efficacy andenhancing the danger of contrary sertraline reactions in patients with MDD.METHODS: A prospective cohort research was designed to find the link between genetic polymorphism in (CYP2B6 and CYP2C19) and the efficacy and/or adverse effects of sertraline in patients with MDD. A convenient sampling strategy was used in the study. The 17-item Hamilton Depression Rating Scale (HDRS) was used to evaluate the therapeutic response of sertraline, and the LUNSER scale was used to evaluate side effects that sertraline may have caused.RESULTS: In our study, non-responder phenomenon was 53.33%. No statistically significant difference was found in genotype frequencies between the responders and nonresponders. The genotype frequencies of the SNPs showed no statistically significant difference between the responders and nonresponders. However, a statistical significant difference was found in HDRS mean scores between respondersand non-responders in the 12th week but no statistical significant difference was found in LUNSERS mean scores between responders and nonresponders.CONCLUSION: In conclusion, our data suggest that genetic polymorphisms in CYP2B6 and CYP2C19 genes (21563C>T) and (681G>A), respectively, do not significantly influence sertraline efficacy and safety profile.
Role of personalized medicine in silico
Authors: Bangash Fawad
Published: December 2024

Hemorrhagic Cystitis (HC) is the primary side effect associated with the use of cyclophosphamide (CYP) in cancer patients. Acrolein, the urotoxic metabolite of CYP, induces oxidative stress, lipid peroxidation, and generation of proinflammatory cytokines leading to urothelial damage, hemorrhage, edema, and inflammation. Isovanillin, a plant-derived phenolic aldehyde, has shown antioxidant and anti-inflammatory activities in chemically induced rodent models. Therefore, in the present study, we investigated the uroprotective potential of isovanillin in female Sprague Dawley rats having HC induced by CYP (150 mg/Kg, 1, 4, and 7th day once i.p.). Three doses of isovanillin (5, 10, and 20 mg/kg) were evaluated in rats. On the 8th day, the urinary bladder samples were isolated and collected for in vitro studies. Pre-treatment with isovanillin decreased bladder weight, edema, hemorrhage, and nociception scoring in rats. Isovanillin also increased GSH, GST, and CAT activity and reduced lipid peroxidation in rats treated with CYP. Expression of TNF-α, Caspase 1, and iNOS were reduced in the isovanilline pretreatment groups while the expression of SOD increased. In silico studies presented isovanillin as a strong candidate for antioxidant, and anti-inflammatory activities with high lipophilicity, bioavailability, and safety profile. The findings of the current study present isovanillin as a uroprotective, antioxidant, and anti-inflammatory agent against HC induced by CYP. Consequently, isovanillin has the potential to be used as a potential adjuvant drug for CYP-based chemotherapy.
Assessment of Acute and Chronic Toxicity of the Active Fraction of Lavandula stoechas in Albino Mice: A Comprehensive Study
Authors: Mushtaq Aamir , Rehman Tanzeela , Shah Hamid Saeed , Kamran Sairah Hafeez , Hussain Amjed , Ain Qurat Ul , Gohar Umar Farooq
Published: December 2024

This study builds upon prior research where the principal components, phenethylamine and α-tocopherol, of Lavandula stoechas (L. stoechas) were identified as responsible for its nootropic potential. The current investigation aimed to determine the acute and xchronic toxicity profiles of the active fraction of L. stoechas (AfL.s) in albino mice. Acute toxicity assessment involved oral administration of AfL.s at doses of 350 mg/Kg and 300 mg/Kg, with toxicity signs monitored for 72 hours. For chronic toxicity evaluation, two groups of mice were administered either 10 ml/kg P.O. of normal saline or 18 mg/Kg P.O. of AfL.s daily for three consecutive months. At the end of the 90-day period, blood sampling was done via cardiac puncture to perform hematological and biochemical analyses. Additionally, the brain and liver were harvested for histopathological examination. The acute toxicity study revealed that AfL.s induced hyper excitation, convulsions, ataxia, muscle spasms, and blanching in mice. Chronic toxicity evaluation indicated that a dose of 18 mg/Kg P.O. of AfL.s led to non-significant (P ≥ 0.05) alterations in hematological parameters; RBC count, platelet count, hemoglobin and serum biochemistry; cholesterol, creatinine, glucose, AST (aspartate transaminase), ALT (alanine aminotransferase), and TB (total bilirubin). However, WBC count, hematocrit, and alkaline phosphatase (ALP) levels exhibited slight increases, accompanied by a significant (P ≤ 0.05) reduction in body weight in the treated mice. Histopathological assessments did not reveal any signs of toxicity. Consequently, AfL.s at an oral dose of 18 mg/Kg P.O. is deemed safe for long-term use in mice.
Extended SIRU model with dynamic transmission rate and its application in the forecasting of COVID-19 under temporally varying public intervention
Authors: Jiang Yiye , Vergara-Hermosilla Gaston
Published: December 2024

By considering the recently introduced SIRU model, in this paper we study the dynamic of COVID-19 pandemic under the temporally varying public intervention in the Chilean context. More precisely, we propose a method to forecast cumulative daily reported cases CR(t), and a systematic way to identify the unreported daily cases given CR(t) data. We firstly base on the recently introduced epidemic model SIRU (Susceptible, Asymptomatic Infected, Reported infected, Unreported infected), and focus on the transmission rate parameter τ. To understand the dynamic of the data, we extend the scalar τ to an unknown function τ(t) in the SIRU system, which is then inferred directly from the historical CR(t) data, based on nonparametric estimation. The estimation of τ(t) leads to the estimation of other unobserved functions in the system, including the daily unreported cases. Furthermore, the estimation of τ(t) allows us to build links between the pandemic evolution and the public intervention, which is modeled by logistic regression. We then employ polynomial approximation to construct a predicted curve which evolves with the latest trend of CR(t). In addition, we regularize the evolution of the forecast in such a way that it corresponds to the future intervention plan based on the previously obtained link knowledge. We test the proposed predictor on different time windows. The promising results show the effectiveness of the proposed methods.
El mito en proceso de reescritura: apuntes desde la poesía peruana contemporánea
Authors: Hernandez Biviana
Published: December 2024

El artículo busca indicar algunos lineamientos estéticos de la poesía peruana contemporánea a partir de la reescritura de mitos vinculados con los relatos de fundación del territorio local y con las tradiciones helenístico-judeocristianas. En específico, hará foco en las autorías de Martín Rodríguez-Gaona (Códex de los poderes y los encantos, 2011), Miguel Gil Castro (Cinco días en Huarochirí, 2022) y Andrés Piñeiro (La colina de los muertos, 2017), con el propósito de revisar de qué manera en sus (re)escrituras el mito se articula como una poética hipertextual, de carácter documental, que dialoga con el archivo literario e historiográfico de la nación peruana.