bluuebunny/crossref_metadata_2025 huggingface dataset:
Development and Validation of a Virtual Moving Auditory Localization (vMAL) Test among Healthy Children
Authors: Hilmi Che Hassan Muhammad Nur , Zakaria Mohd Normani , Wan Mohamad Wan Najibah
Published: January 2023

Introduction: The ability to localize sound sources is crucial for humans. Due to specific hearing disorders, the affected individuals may have problems to accurately locate the sound sources, leading to other unwanted consequences. Nevertheless, a simple auditory localization test (that employs moving auditory stimuli) is currently lacking in clinical settings. Essentially, the objectives of the present study were to develop a virtual moving auditory localization (vMAL) test that is suitable for assessing children and assess the validity and the reliability of this test. Materials and Methods: This study consisted of two consecutive phases. In phase 1, the required stimulus and the test set up for the vMAL test were established. Two loudspeakers were employed to produce five virtual positions, and eight different moving conditions were constructed. In phase 2, 24 normal-hearing Malaysian children (aged 7-12 years) underwent the vMAL test. The validity and the reliability of this test were then assessed using several validation measures. Fleiss Kappa and Spearman correlation analyses were used to analyse the obtained data. Results: The vMAL test was found to have good convergent validity (kappa = 0.64) and good divergent validity (kappa = -0.06). Based on the item-total correlation and Spearman coefficient rho results, this test was found to have good internal reliability (rho = 0.36-0.75) and excellent external (test-retest) reliability (rho = 0.99). Conclusions: in this study a new vMAL test was developed and proven to be valid and reliable accordingly for its intended applications. This test can be useful in clinical settings since it is simple to administer, cost-effective, does not take up much room, and can assess auditory localization performance in children. The outcomes of the present study may serve as preliminary normative data as well as guidelines for future auditory localization research.
Resilience for critical facilities
Authors: Scott Donald R , Cerino A Christopher , Pekelnicky Robert G , Yu Kent
Published: January 2023

The three categories of critical facilities addressed in this document are hospitals, K-12 educational facilities, and data centers. This review focuses on both requirements for new building design as well as for existing building renovations or additions for the flood, wind, and seismic hazards. An overall review of current design practices for these three categories of critical facilities within our communities is discussed, along with some of the best practices currently being utilized to provide more resilience within these facilities. The target audience of this report includes industry associations, design professionals, building code officials, city planners, and researchers.
Administering accessible vote by mail systems
Authors: Laskowski Sharon J , Quesenbery Whitney , Baumeister Lynn
Published: January 2023

Accessible vote by mail (AVBM) provides options for voters with disabilities to complete their absentee or vote by mail ballots independently and privately. AVBM is especially important for voters with print disabilities that make it difficult to read or handle paper. This report reviews current elections offices practices in administering accessible vote by mail and considers their innovations and current challenges. One of the most important challenges is difficulties exchanging voter data and ballot style information between the election management systems and the AVBM system. A strong Common Data Format for ballot style data interchange would make providing AVBM more efficient. With the use of AVBM and electronic ballot return growing, strong standards will also support stronger cybersecurity practices while providing voters with print disabilities equal access to voting by mail. Recommendations include gathering more detailed information about administrative practices, assessing the risks and benefits for different methods of electronic return, and investigating methods for directly counting an AVBM ballot without replication, including best practices for how voter selections are encoded.\
Handbook for VVSG 2.0 usability and accessibility test strategies
Authors: Laskowski Sharon J , Quesenbery Whitney
Published: January 2023

This document provides guidance and resources for how to test voting systems against the usability and accessibility requirements in the Voluntary Voting System Guidelines (VVSG) 2.0. The requirements include Principles 2.2 and 5 through 8. The goal of those requirements is to ensure that voting systems certified to VVSG 2.0 are accessible and usable for election workers and voters including voters with disabilities so that every voter can mark, review, cast, and verify their ballot independently and privately. The primary audiences for this guide are the voting system test laboratory organizations who perform certification testing, to help them understand some of the specialized tests required, and organizations in the design and development process as they build and prepare a voting system for certification testing.
Expectativas de los padres y rendimiento en las enseñanzas musicales: Un acercamiento desde el Efecto Pigmalión
Authors: Campayo Muñoz Emilia
Published: January 2023

Las expectativas de los padres hacia el desempeño musical de sus hijos pueden ejercer una influencia decisiva en el rendimiento de éstos. Dada la importancia de esta temática, este estudio explora la interconexión entre el rendimiento de una alumna en las enseñanzas elementales de piano en un conservatorio en España y las expectativas de sus padres respecto a dichos estudios. También se pretende dar respuesta a la carencia de literatura que aborda esta cuestión. Para ello, se indagó acerca de las expectativas de los padres y de la propia alumna a través de una entrevista semiestructurada. Además, la profesora-investigadora realizó un seguimiento de la alumna a lo largo de todo el curso escolar en el marco de la asignatura de piano con tal de recoger datos relacionados con el desempeño musical de la estudiante a través de la observación participante. Los resultados sugieren que las expectativas de los padres ejercen una influencia significativa en el rendimiento de los estudios musicales de la niña.
MOTIVACIÓN Y FORMACIÓN CONTINUA DE DOCENTES DE ARTES EN EDUCACIÓN BÁSICA EN EL ESTADO DE CHIHUAHUA, MÉXICO
Authors: Muñoz Jiménez Anna Patricia , González-Moreno Patricia A.
Published: January 2023

La formación continua de los docentes de artes es un requisito indispensable para su desarrollo profesional y su percepción de eficacia y competencia en la enseñanza. Se realizó el presente estudio con el objetivo de conocer la oferta de formación continua a la que tienen acceso los maestros de artes de nivel básico del estado de Chihuahua, México, así como los factores que motivan su participación en programas de actualización docente. Se tomó como marco teórico el Modelo de Expectativas y Valores de Eccles y Wigfield. Los datos fueron analizados mediante estadísticos descriptivos e inferenciales (MANOVA). Esto permitió examinar las diferencias entre las necesidades de capacitación y motivación de los docentes de distintas especialidades artísticas, así como en función del sistema (estatal, federal y/o privado) y nivel educativo (preescolar, primaria y/o secundaria) en el que laboraban. Se identificaron los principales factores que dificultaban la asistencia de los maestros a los programas de formación continua, como la falta de oferta por parte del sistema educativo. Se pudo conocer tanto las necesidades de formación reportadas como que los docentes le dan gran importancia a su capacitación continua. También los docentes indicaron tener altos niveles de competencia en actividades pedagógicas, artísticas y musicales.
Entrevista Gabriel Rusinek por Ana M. Vernia
Authors: Vernia Carrasco Ana Mercedes
Published: January 2023

El Dr. Gabriel Rusinek es Profesor Titular de Universidad en la Facultad de Educación de la Universidad Complutense de Madrid. Sus trabajos de investigación se han centrado sucesivamente en el aprendizaje musical significativo, la composición cooperativa, las pedagogías inclusivas en educación musical, la experiencia del público en las artes escénicas, la evaluación de programas educativos, la evaluación del impacto de la educación musical escolar en España y la formación del profesorado de música. Ha presentado comunicaciones y ponencias en numerosos congresos y seminarios nacionales e internacionales, y es miembro activo de la Sociedad Internacional para la Educación Musical (ISME), en cuya Comisión para la Música en las Escuelas y Formación del Profesorado (MISTEC) se desempeñó como comisionado entre 2010 y 2016. Ha sido fundador y director de la Revista Electrónica Complutense de Investigación en Educación Musical (http://revistas.ucm.es/index.php/RECI), siendo actualmente miembro de su Consejo Editorial y del de la Revista Internacional de Educación Musical y de Music Education Research. Ha participado en diversos proyectos investigación de financiación nacional e internacional, y es actualmente co-director del grupo de investigación Estudios sobre Comunicación y Lenguajes para la Inclusión y la Equidad Educativa (ECOLE).
Gateways to the Internet Ecosystem – Enabling and Discovery Tools in the Age of Global Online Platforms
Authors:   Digital Markets Working Group of the Hungarian Competition Law Association, Firniksz Judit ,   Competition Law Center of Law at Pázmány Péter Catholic University, Dömötörfy Borbála Tünde ,   Competition Law Center of Law at Pázmány Péter Catholic University,   Réti, Várszegi and Partners Law Firm PwC Legal, Mezei Péter ,   Digital Markets Working Group of the Hungarian Competition Law Association,   Hegymegi-Barakonyi and Partner Baker & McKenzie Attorneys-at-Law
Published: January 2023

The Google Shopping case has provided significant lessons that reach beyond antitrust enforcement. ‘Enabling and discovery tools’ create a layer that serves as a gateway to the Internet ecosystem. Therefore, on the one hand, they play a key role in ensuring the openness of the Internet ecosystem, and on the other hand, they exercise a primary influence on consumer experiences and their cognitive processes, which in turn determine online consumer transactions. Enabling and discovery tools, such as adopting design methods based on applied behavioural sciences (for example: user experience design (UX) and user interface design (UI)), create global challenges at the crossroads of antitrust, consumer law and platform regulation. At the same time, in light of the complexity of the platform economy, some market phenomena might be particularly difficult to identify and address, while fast and efficient adaptation is an essential factor for market players. This brings advocacy – the promotion of a competitive environment – into the focus also at the national level, particularly where a dual enforcement regime makes a multifocal approach possible.
The Housekeeping of the Court of Justice: The ne bis in idem Principle and the Territorial Scope of NCA Decisions. Case Comment to the Nordzucker Judgment of the Court of Justice of 22 March 2022, Case C-151/20
Authors:   Department of Regulatory Policies at Cracow University of Economics, Dobosz Kamil
Published: January 2023

The case commentary examines the recent ruling of the Court of Justice in the Nordzucker case. This judgment is important not only for the new approach to the ne bis in idem principle in competition law (which was first established in the Bpost case, issued the same day), but also for the clarification of the concept of “idem” with respect to the territorial effects of the infringement on the territories of two member states. The judgment thus provides guidance for the extraterritorial application of EU competition law.
Rozliczenie obowiązku uzyskania oszczędności energii opłatą zastępczą
Authors:   Zakład Publicznego Prawa Gospodarczego Uniwersytetu Wrocławskiego, Szczęśniak Krzysztof
Published: January 2023

Artykuł opisuje zasady rozliczania obowiązku efektywności energetycznej poprzez uiszczenie opłaty zastępczej po 2018 roku. Z uwagi na wysokie, utrzymujące się ceny białych certyfi katów w latach 2021 i 2022 podmioty zobowiązane do uzyskania oszczędności energii są zainteresowane właśnie takim sposobem rozliczeń. Przepisy ustawy o efektywności energetycznej dotyczące opłaty zastępczej sformułowano jednak w sposób nieprecyzyjny, jeżeli nie powiedzieć wadliwy. Powoduje to poważne wątpliwości praktyczne. W szczególności interesujące jest pytanie czy skuteczne, nawet jednorazowe nabycie białych certyfi katów wyłącza możliwość uiszczenia opłaty zastępczej.
Prosument, prosument wirtualny i prosument zbiorowy energii elektrycznej – uwagi krytyczne
Authors:   Katedra Prawa i Ubezpieczeń na Wydziale Finansów Uniwersytetu Ekonomicznego w Katowicach, Budka Borys
Published: January 2023

Celem niniejszego artykułu jest wskazanie konsekwencji, szczególnie o praktycznym charakterze, które wynikają z wprowadzenia do polskiego porządku prawnego nowych pojęć: „prosumenta”, „prosumenta zbiorowego” i „prosumenta wirtualnego” energii elektrycznej. Autor podejmuje próbę oceny implementacji rozwiązań unijnych pod kątem jej skutków w zakresie prawa energetycznego, a także systemu ochrony konsumenta i konkurencji. Autor stoi na stanowisku, że regulacja polskiego ustawodawcy w aktualnym brzmieniu może powodować ryzyko występowania nieprawidłowości w zakresie umów zawieranych pomiędzy prosumentami a przedsiębiorstwami energetycznymi, co może w znaczącym stopniu spowolnić wzrost prosumeryzmu na rynku polskim.
Specustawa jądrowa i prawo atomowe (ocena wybranych planów legislacyjnych)
Authors:   Zespół Badawczy Prawa Administracyjnego, Nowych Technologii i Prawa Kosmicznego, Wydział Prawa i Administracji, Uniwersytet Szczeciński, Dubiński Łukasz
Published: January 2023

W artykule omówiono plany ustawodawcy dotyczące tzw. specustawy jądrowej oraz prawa atomowego. Analiza została przeprowadzona pod kątem założenia projektodawcy, zgodnie z którym nowelizacja przywołanych ustaw miałaby się przełożyć na usprawnienie postępowań w sprawie inwestycji dotyczących obiektów jądrowych. Ogólna ocena przygotowywanych zmian legislacyjnych jest pozytywna.
Sąd jako gwarant ochrony praw stron postępowania dotyczącego naruszenia prawa konkurencji – obserwacje na tle wybranych postępowań w toku
Authors:   Departament Prawa Konkurencji Baker McKenzie Krzyżowski i Wspólnicy sp.k, Trepka Marcin , Buczkowska Elżbieta ,   Departament Prawa Konkurencji Baker McKenzie Krzyżowski i Wspólnicy sp.k
Published: January 2023

Celem artykułu jest przedstawienie stale kształtującej się roli SOKiK w postępowaniu odwoławczym od decyzji Prezesa Urzędu oraz wyzwań, które stoją przed SOKiK w związku z dynamicznym rozwojem prawa konkurencji Unii Europejskiej oraz w konsekwencji – prawa krajowego. Autorzy dokonują tego przedstawienia na tle niedawno wydanych jednej decyzji Prezesa Urzędu oraz dwóch rozstrzygnięć sądowych. W przywołanej decyzji Prezesa Urzędu koncepcja single economic unit wykorzystana została po raz pierwszy jako narzędzie egzekwowania przestrzegania prawa konkurencji. Pierwsze ze wspomnianych postępowań dotyczy wyznaczenia granicy, do której przeprowadzenie przez SOKiK pełnego postępowania dowodowego winno prowadzić do uchylenia decyzji Prezesa Urzędu, nie zaś wydania rozstrzygnięcia o charakterze reformatoryjnym. Drugie z nich dotyczy natomiast dopuszczalności wstąpienia do postępowania odwoławczego od decyzji Prezesa Urzędu przez podmiot, który nosi się z zamiarem wszczęcia postępowania prywatnoprawnego dotyczącego tego samego naruszenia prawa konkurencji, co naruszenie ustalone w spornej decyzji ww. organu. Opierając się na przedstawionych rozstrzygnięciach autorzy uzasadniają tezę o rosnącej roli SOKiK w zapewnieniu spójności stosowania prawa konkurencji, rosnących oczekiwaniach wobec SOKiK oraz znaczeniu uważnego i wyważonego podejścia SOKiK do przedstawionych zagadnień prawnych dla ochrony interesów stron postępowania dotyczącego naruszenia prawa konkurencji.
Błędy proceduralne organu w postępowaniu antymonopolowym w sprawach praktyk ograniczających konkurencję a kompetencje Sądu Ochrony Konkurencji i Konsumentów
Authors:   Wardyński i Wspólnicy, Bolecki Antoni
Published: January 2023

Celem niniejszego artykułu jest przybliżenie czytelnikowi zagadnienia dotyczącego możliwości uchylenia przez SOKiK decyzji Prezesa UOKiK z powodu błędów proceduralnych popełnionych w toku postępowania antymonopolowego. Autor, opierając się na orzecznictwie oraz poglądach przedstawicieli doktryny, podejmuje próbę wyróżnienia otwartego katalogu błędów proceduralnych, które uzasadniają uchylenie decyzji Prezesa UOKiK oraz takich, które nie stanowią do tego wystarczającej podstawy.
Odpowiedzialność odszkodowawcza za szkody antymonopolowe wyrządzone przez spółki powiązane – rozwój koncepcji jednolitego organizmu gospodarczego Glosa do wyroku TSUE z 6 października 2021 r. w sprawie C-882/19 Sumal SL przeciwko Mercedes Benz Trucks España SL
Authors:   Akademia Leona Koźmińskiego w Warszawie, Mackiewicz Marta ,   Kancelaria Maruta Wachta Sp. J
Published: January 2023

Przedmiotem niniejszej glosy jest analiza i ocena wyroku Trybunału Sprawiedliwości Unii Europejskiej (dalej: TSUE) wydanego dnia 6 października 2021 r. w sprawie C-882/19 z powódzwa Sumal SL przeciwko Mercedes Benz Trucks España SL. Wyrok w sprawie Sumal dotyczy istotnego zagadnienia w obszarze prawa konkurencji zarówno publicznego, jak i prywatnego (private enforcement), tj. ustalenia kręgu podmiotów odpowiedzialnych za naruszenia prawa konkurencji działających w ramach jednego organizmu gospodarczego. Dotychczasowe orzecznictwo TSUE w tym zakresie koncentrowało się przede wszystkich na ustaleniu odpowiedzialności spółki dominującej (matki) w grupie spółek. W wyroku w sprawie Sumal, TSUE podjął kwestię odpowiedzialności spółek zależnych (córek), w sytuacji naruszenia prawa konkurencji przez spółkę matkę. TSUE nie przekreślił w żadnym wypadku dotychczasowego orzecznictwa TSUE dot. single economic unit, uszczegółowił jedynie warunki odpowiedzialności spółek zależnych. Owe doprecyzowanie było niewątpliwie pożądane. Niemniej stawia pod znakiem zapytania zasadę odpowiedzialności spółek zależnych w sytuacji, gdy nie brały one bezpośrednio udziału w naruszeniu, ale w sposób pośredni lub nieformalny.
Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration
Authors: Travis Amanda M , Manocha Samiya , Willer Jason R , Wessler Timothy S , Skiba Nikolai P , Pearring Jillian N
Published: January 2023

The small GTPase Arl3 is important for the enrichment of lipidated proteins to primary cilia, including the outer segment of photoreceptors. Human mutations in the small GTPase Arl3 cause both autosomal recessive and dominant inherited retinal dystrophies. We discovered that dominant mutations result in increased active G-protein—Arl3-D67V has constitutive activity and Arl3-Y90C is fast cycling—and their expression in mouse rods resulted in a displaced nuclear phenotype due to an aberrant Arl3-GTP gradient. Using multiple strategies, we go on to show that removing or restoring the Arl3-GTP gradient within the cilium is sufficient to rescue the nuclear migration defect. Together, our results reveal that an Arl3 ciliary gradient is involved in proper positioning of photoreceptor nuclei during retinal development.
Metformin protects trabecular meshwork against oxidative injury via activating integrin/ROCK signals
Authors: Xu Lijuan , Zhang Xinyao , Zhao Yin , Gang Xiaorui , Zhou Tao , Han Jialing , Cao Yang , Qi Binyan , Song Shuning , Wang Xiaojie , Liang Yuanbo
Published: January 2023

This study aimed to investigate the protective effect of metformin on trabecular meshwork (TM) and explore its molecular mechanisms in vivo and in vitro. Ocular hypertension (OHT) mouse models were induced with dexamethasone and further treated with metformin to determine the intraocular pressure (IOP)-lowering effect. Cultured human TM cells (HTMCs) were pre-stimulated with tert-butyl hydroperoxide (tBHP) to induce oxidative damage and then supplemented with metformin for another 24 hr. The expression of fibrotic markers and integrin/Rho-associated kinase (ROCK) signals, including α-smooth muscle actin (α-SMA), transforming growth factor-β (TGF-β), fibronectin, integrin beta 1, ROCK 1/2, AMP-activated protein kinase, myosin light chain 1, and F-actin were determined by western blotting and immunofluorescence. Reactive oxygen species (ROS) content was analysed using flow cytometry. Transmission electron microscopy was performed to observe microfilaments in HTMCs. It showed that metformin administration reduced the elevated IOP and alleviated the fibrotic activity of aqueous humour outflow in OHT models. Additionally, metformin rearranged the disordered cytoskeleton in the TM both in vivo and in vitro and significantly inhibited ROS production and activated integrin/ROCK signalling induced by tBHP in HTMCs. These results indicated that metformin reduced the elevated IOP in steroid-induced OHT mouse models and exerted its protective effects against oxidative injury by regulating cytoskeleton remodelling through the integrin/ROCK pathway. This study provides new insights into metformin use and preclinical evidence for the potential treatment of primary open-angle glaucoma.
Retrospective validation of bone risk stratification criteria for men with de novo metastatic hormone-naive prostate cancer in China
Authors: Zhang Yang , Ding Li , Zheng Yuxin , Wang Kun , Xia Wentao , Wang Junqi , Ge Peng
Published: January 2023

Background

Bone metastasis has been suggested to be a significant impactor on the prognosis of newly diagnosed de novo metastatic hormone-sensitive prostate cancer (mHSPC), and some risk stratification models have been proposed on the basis of this hypothesis. However, the effectiveness of these risk stratification criteria has not been fully evaluated in China. This study aimed to evaluate the effectiveness of the risk stratification models in China.

Methods

A total of 140 patients who were newly diagnosed with metastatic prostate cancer followed by primary androgen deprivation-based therapy from January 2008 to June 2021 at our institution were enrolled in this study. The patients were divided into different groups on the basis of high- and low-volume disease (H/LVD) criteria, high-and low-risk disease (H/LRD) criteria, extremity bone metastasis criteria (EBM), and extent of disease (EOD) criteria. The area under the receiver operating characteristic (ROC) curve (AUC) and decision curve analysis (DCA) were used to compare the validity and net benefit of these models. Using the Cox proportional hazards model, we performed univariable and multivariable analyses of the factors influencing overall survival (OS) and the time of progression to metastatic castration-resistant prostate cancer (CRPC).

Results

The median patient age was 72 years. Most patients had a Gleason score ≥8 (102 cases, 72.9%) and clinical T stage >2 (75 cases, 53.6%). The median follow-up time was 25 months (range, 2–95 months). Ninety-two patients progressed to CRPC and fifty-seven patients died during the follow-up. The AUC of OS and CRPC showed that the EOD model had higher validity than the other risk stratification models. DCA shows that the net benefit of the EOD model on OS was better than that of the other risk stratification models. As for CRPC, the net benefit of the EOD model was second only to that of the H/LRD model when the threshold was <0.5; however, when the threshold was >0.5, the EOD model outperformed the other models. The effectiveness of EOD as an independent prognostic variable was verified through univariable and multivariable analyses.

Conclusion

The EOD model yields reasonable risk stratification for use in Chinese mHSPC patients, providing further evidence supporting its role in clinical decision-making.
Comparison of the Perceptions of Organizational Democracy of Educators Working in Turkish Historical Schools and Minority Schools
Authors: GÜÇTEKİN Nuri , EKTİREN Mahmut Turan
Published: January 2023

In this study, the perceptions of organizational democracy of Turkish historical schools and minority schools with historical roots in Istanbul were compared. Population of the study: The study included 21 minority schools with the
private school status, 16 of which belonged to the Armenian community, 4 of which belonged to the Greek community, and 1 of which belonged to the Jewish community, and 15 Turkish historical schools affiliated with the Ministry
of National Education, which have been in service since the Republican Period, in Istanbul. The sample consisted of school administrators and teachers who were selected from these schools on a voluntary basis. A descriptive research
model was used to compare the perceptions of organizational democracy of educators working in Turkish historical schools and minority schools. Employees of minority schools are mostly members of the community which the educational
institution educates. The fact that minority schools have a long history like Turkish historical schools and they may have an institutionalized organizational culture in this context has been important for our study. The data were
collected via the "Organizational Democracy Scale" developed and studied for validity and reliability by Geçkil & Tikici (2015). The data obtained through scale and questionnaire were analyzed using SPSS 22 Program. As a result
of the study, the perceptions of organizational democracy of the participants working in Turkish historical schools were found to be lower than those of the participants working in minority schools. There was a significant difference
between the perceptions of organizational democracy of educators working in Turkish historical schools and minority schools in favor of those working in minority schools. In this context, educators working in minority schools were
observed to have higher levels of perception of democracy.
Adolescents' Social and Emotional Experiences of Online Games in the Distance Education Process
Authors: ARICI DOĞAN Duygu , PAMUK İrem
Published: January 2023

Günümüzde yüz yüze doğal ortamlarda oynanan oyunların yerini teknolojik gelişmelerle birlikte çevrimiçi oyun türleri almıştır. Bu oyunları oynayan kişi sayısı her geçen gün artmakta ve ergenler de bu oyunları oynamak için zamanlarının
büyük bir bölümünü bilgisayar başında geçirmektedir. Eğitimin Covid-19 pandemisi nedeni ile zorunlu olarak uzaktan hale gelmesi ile de öğrenciler çevrimiçi ortamlarda daha fazla vakit geçirmeye başlamıştır. Bu bağlamda bu araştırmanın
amacı, ergenlerin uzaktan eğitim sürecinde çevrimiçi oyunlara yönelik sosyal ve duygusal deneyimlerinin incelenmesidir. Bu araştırma için; Sağlık Bilimleri Üniversitesi, Hamidiye Girişimsel Olmayan Araştırmalar Etik Kurul’undan
29.01.2021 tarih ve 21/101 sayılı karar ile etik izin alınmıştır. Çalışma nitel araştırma yöntemlerinden biri olan fenomenolojiye (olgubilim) göre desenlenmiştir. Araştırmanın çalışma grubunu 2020-2021 eğitim-öğretim yılında İstanbul
ilinde bulunan, amaçlı örnekleme yöntemi ile belirlenen 22 ergen (lise öğrencileri) oluşturmaktadır. Ergenlerin demografik bilgilerini içeren “Kişisel Bilgi Formu” ve veri toplama aracı olarak bu çalışmada; araştırmacılar tarafından
hazırlanan yarı yapılandırılmış görüşme formu kullanılmıştır. Elde edilen verilerin analizi betimsel analiz ve içerik analizi ile gerçekleşmiştir. Uzaktan eğitim sürecinde çevrimiçi oyun oynarken ergenlerin farklı birçok duyguyu
bir arada yaşadıkları, bazılarının gerçek yaşamına da yaşadıkları bu duyguları yansıttığı ortaya çıkmıştır. Arkadaşlık ilişkilerini pekiştirerek yeni arkadaşlıklar edindikleri fakat aile ilişkilerinde problemler yaşadıkları da
araştırmadan elde edilen sonuçlar arasında yer almaktadır.
Examination of Secondary Education Teachers' Opinions on Organizational Culture
Authors: ULUSOY Berru , AKDENİZ KOÇYİĞİT
Published: January 2023

Eğitim sisteminin parçası olan okullar, eğitim hizmetini sunan örgütlerdir. Her okulun kendine özgü karakteri ve özelliği vardır. Okullar eğitim hizmeti üretirken ortak amaçlar benimsese de farklı dinamiklerden oluşmaktadır. Okulun
paydaş üyelerinin benimsediği değerler, inançlar, normlar ve kültürel öğeler okulun kültürünü oluşturmaktadır. Okullar, üzerinde çalıştığı hammaddenin insan olması sebebiyle toplumda gelişmeler ve değişmeler meydana getirir. Dolayısıyla
eğitim kurumlarının sahip olduğu örgüt kültürü sadece bulundukları okul örgütünü değil, toplumu da etkisi altına almaktadır. Okullarda örgüt kültürünün oluşmasına başta okul yöneticileri olmak üzere öğretmenler, veliler ve öğrenciler
katkı sağlamakta; okulun tüm paydaşları özellikle örgütün amaçlarını gerçekleştirmek için çaba harcamaktadır. Okulun amaçları arasında öğrenci başarısının sağlanması, verimli ve kaliteli eğitim hizmetinin sunulması yer almaktadır.
Öyle ki okulların amaçlarına ulaşmasını etkileyen en önemli etkenlerden biri de okulda var olan örgüt kültürüdür. Konuyla ilgili alanyazında yapılan araştırmalar değerlendirildiğinde okulların amaç ve hedeflerinin gerçekleştirilmesinde
okullardaki örgüt kültürünün ne kadar önemli bir unsur olduğu görülmektedir. Bu önem doğrultusunda araştırmada ortaöğretim kurumlarında çalışan öğretmenlerin örgüt kültürüne ilişkin görüşlerinin incelenmesi amaçlanmıştır. Araştırmanın
çalışma grubunu; amaçlı, maksimum çeşitlilik ve kolay örnekleme yöntemine göre seçilmiş, 2021-2022 eğitim öğretim yılında Ordu ilindeki çeşitli kamu ortaöğretim kurumlarında görev yapan 33 öğretmen oluşturmaktadır. Araştırmada
veri toplama aracı olarak yarı yapılandırılmış görüşme formu kullanılmıştır. Görüşme formları için 27.04.2022 tarih ve 21/33 sayılı karar ile Giresun Üniversitesi Sosyal Bilimler Fen ve Matematik Bilimleri Araştırma Etik Kurulu’ndan
gerekli izin alınmıştır. Elde edilen veriler içerik analizi ile çözümlenmiştir. Araştırma sonucunda okullarda güçlü bir örgüt kültürü oluşturulması için ortak amaçlar belirlemenin, bu amaçlara ulaşmak için birlikte hareket etmenin
ve işbirliği içinde çalışmanın gerekli olduğu bulgusuna ulaşılmıştır. Araştırmaya katılan öğretmenlerin çoğunluğunun görüşleri doğrultusunda şu an çalıştıkları kurumlarda güçlü bir örgüt kültürü olduğu sonucuna ulaşılmıştır. Elde
edilen bulgulara göre öğretmenlerin çalıştıkları kurumda uzun bir geçmişi olmasa da örgüt kültürünün paydaşı olabildiği görülmektedir. Ayrıca araştırmada, elde edilen sonuçlar doğrultusunda ortaöğretim kurumlarında güçlü bir örgüt
kültürü oluşturmaya ilişkin öneriler sunulmuştur.
The Relationship Between Sense of Family Belonging and Academic Motivation of University Students During the COVID-19 Pandemic
Authors: Deniz GÜNAYDIN Hatice , TÜRKER Ahmet Vahdi , DOLU Fatma Nur , ÖZKAN İshak , BİRİNCİ Gökçe Gürdil , DEMİRKAN Melisa , ULUSAN Dilara Zeynep , ÖZÇELİK Senem Nur
Published: January 2023

In this paper, we aimed to determine the academic motivation levels of university students in terms of family belonging and various demographic factors during the pandemic period. 238 university students (184 female, 54 male) in Turkey
participated. Data were collected using demographic information form, Sense of Family Belonging, and Academic Motivation Scales. The University Ethics Committee reviewed the present study, and ethical committee approval was obtained
according to the ethics committee's decision dated October 26, 2021, and numbered 2021/08-2. The data were examined with arithmetic mean, correlation and stepwise regression analysis, t-test, and ANOVA test. When the academic motivation
and its sub-dimensions were evaluated in terms of the gender of the participants, it was seen that the female participants had higher extrinsic motivation, intrinsic motivation, and overall academic motivation scores than male
participants. In contrast, male participants had higher amotivation scores. It was found that participants infected with COVID-19 had higher amotivation scores. Step-by-step regression analysis revealed that being a female and
self-belonging significantly predicted intrinsic motivation in a positive direction. Although a variety of research has been undertaken to measure students' academic motivation during non-pandemic times, relatively few studies
have been conducted during pandemics. This circumstance is the novel aspect of the present investigation. This research may serve as a guide for establishing the steps to be implemented by relevant institutions and organizations
during the epidemic to boost the academic motivation levels of students.
Comparative Evaluation of Serum Interleukin-6 Expression with Neutrophil-lymphocyte Ratio and Platelet-lymphocyte Ratio in Pre and Post Surgery Oral Squamous Cell Carcinoma Patients: A Research Protocol
Authors: Bhargava Pragati A , Bhowate Rahul R
Published: January 2023

Introduction: Oral Squamous Cell Carcinoma (OSCC) is the 3rd most common malignancy. In Indian scenario, oral submucous fibrosis is the most common condition associated with OSCC. Pre and postsurgical evaluation of serum Interleukin-6 (IL-6), Neutrophil Lymphocyte Ratio (NLR) and Platelet Lymphocyte Ratio (PLR) will help in predicting the prognosis, along with planning of postsurgical treatment protocol. The NLR and PLR are easily available and cost effective biomarkers from peripheral smear. Need of Study: The IL-6 and NLR are convenient and inexpensive prognostic markers, they could be widely available in routine clinical practice, which might serve as a valuable marker for predicting the prognosis of OSCC and assessing the magnitude of systemic inflammation. Aim: To compare the serum IL-6 with NLR and PLR in pre and postsurgical OSCC patients. Materials and Methods: A prospective analytical study, for duration of two years from December 2020 to October 2022 will be conducted at Department of Oral Medicine and Radiology, Sharad Pawar Dental College and Hospital, Sawangi (Meghe), Wardha, Maharashtra, India, in which total 40 patients from lower and middle socio-economic status and histological confirmed cases of OSCC will be included, after obtaining an informed written consent. A detailed clinical, radiological and histological evaluation of all cases will be recorded in the structured format. Presurgical and postsurgical 5 mL venous blood will be collected for evaluation of IL-6, NLR, Platelet–Lymphocyte ratio. Data analysis will be done using unpaired‘t’ test. For categorical data, Chi-square test will be used to compare the proportions.
Comparison of clozapine doses and tolerability in patients with and without concurrent valproic acid
Authors: Santos Ranel Troy , Mullen Sandra , Crouse Ericka L. , Adams Katie S.
Published: January 2023

Introduction

Valproic acid (VPA) and its various formulations can be given in conjunction with clozapine for seizure prophylaxis or for augmentation in schizophrenia. There is conflicting literature on how VPA affects clozapine metabolism and the incidence of clozapine-related side effects. The purpose of this study is to compare the effects of VPA when given concurrently with clozapine to patients on clozapine monotherapy.

Methods

A retrospective medical record review was completed to identify patients admitted to the inpatient psychiatry unit at an academic medical center with an order for clozapine with and without concurrent VPA from August 7, 2010 to August 7, 2020. The primary outcome was the difference in clozapine doses in patients on clozapine as monotherapy versus dual therapy with VPA. Secondary outcomes include the difference in incidence of adverse effects in monotherapy versus dual therapy, as well as clozapine and norclozapine concentrations in both treatment groups.

Results

During the study period, 73 patients were included in the monotherapy group and 35 patients were included in the dual therapy group. The average clozapine dose in the dual therapy group was 250 mg (95% CI = 194.7, 305.4) which was significantly higher than the average monotherapy dose of 175.9 mg (95% CI = 134.0, 208.7; P = .016). However, there was no significant difference in the average clozapine concentration between the dual therapy group (392.5 ng/mL; 95% CI = 252.8, 532.2) and monotherapy group (365.9 ng/mL; 95% CI = 260.5, 471.3; P = .756). There were higher rates of tachycardia (45.7% vs 17.8%; P = .002), sedation (51.4% vs 8.2%; P < .001), and constipation (42.8% vs 9.5%; P < .001) in the dual therapy group compared to the monotherapy group, respectively.

Discussion

Patients on concurrent clozapine and VPA received higher doses of clozapine and experienced a higher incidence of tachycardia, sedation, and constipation.
Publication rates and characteristics of PGY2 psychiatric pharmacy resident research projects
Authors: Antley Dayton L. , Nelson Leigh Anne , Kriz Carrie R. , Iuppa Courtney A. , Lang Shelby E. , Gramlich Nicole A. , Elliott Ellie S. R. , Sommi Roger W.
Published: January 2023

Introduction

To describe the publication rates and characteristics of PGY2 psychiatric pharmacy residency projects presented as a poster presentation at the annual meetings of the College of Psychiatric and Neurologic Pharmacists (CPNP) from 2002 to 2018. (As of 2022 the organization is under the name, American Association of Psychiatric Pharmacists.)

Methods

CPNP abstracts from even years were strategically searched in PubMed, Ovid MEDLINE, and Google Scholar. If a publication was identified, additional data were collected for characterization, including study information, journal information, author information, institutional affiliation, publication year, and time to publication.

Results

A total of 348 abstracts were evaluated. Publication in a journal was achieved for 60 projects (17.2%), with publication rates decreasing from 2012 to 2018. The mean time to publication was 17.3 months after completion of the residency, with most projects published at 8 months. More than half (51.7%) of these projects were published in a psychiatric pharmacy journal affiliated with CPNP. Study designs were predominantly retrospective, observational, cohort studies with a focus on evaluation of a drug therapy outcome. The PGY2 resident was the first author in 90% of the publications. Forty percent included other health care professionals outside of pharmacy as a coauthor. PGY2 residencies affiliated with academic institutions had overall higher publications rates.

Discussion

Publication rates for PGY2 psychiatric pharmacy residency projects are low and are decreasing over time despite an increasing number of PGY2 psychiatric pharmacy residency programs. This publication rate is lower than that reported in the literature for PGY2 critical care residency programs. The downward trend of publication rates for PGY2 psychiatric pharmacy residency projects is concerning.
A Temática de Propriedade Intelectual como Parte da Formação dos Alunos dos Cursos Técnicos dos Institutos Federais da Região Norte
Authors: Rodrigues Darlene Silveira , Santos Rosa Maria Nascimento dos , Oliveira Raimundo Corrêa de
Published: January 2023

Considerando a importância de divulgar e fornecer conhecimentos essenciais aos alunos do ensino médio técnico sobre a propriedade intelectual, vinculada à inovação e ao empreendedorismo, o objetivo geral do trabalho foi analisar como o ensino técnico, em Institutos Federais de Educação, trata do tema no âmbito curricular. A pesquisa baseou-se na coleta de dados primários (levantamento bibliográfico) e em pesquisa documental. Constatou-se uma lacuna curricular no ensino médio técnico nos Institutos Federais, com relação à abordagem da propriedade intelectual. Devem ser criadas disciplinas específicas tratando do tema, além de atividades curriculares que permitam oferecer conhecimentos aos discentes, capacitando-os para que reconheçam a importância de se proteger a atividade criadora como inovação e base do empreendedorismo. O produto final da pesquisa foi a elaboração de uma história em quadrinhos, como instrumento que pode despertar o interesse dos alunos sobre o tema, considerando o caráter informativo dinâmico, simples, mas com efetivo potencial educacional.
O pensamento pós-moderno e suas implicações na educação ambiental: uma análise materialista histórico-dialética
Authors: De Oliveira Ana Carolina Brasil , Kaplan Leonardo
Published: January 2023

O artigo propõe-se a indicar influências do ideário pós-moderno para a educação ambiental (EA), em termos dos pressupostos epistemológicos e de suas implicações para as práticas escolares. Fundamentando na EA Crítica marxista, discute-se os pressupostos teóricos dos autores pós-modernos. São apresentados resultados parciais da tese de doutorado que investigou a política pública de EA no município de Maricá/ RJ. Por fim, discutimos as implicações deste pensamento na EA em termos das práticas pedagógicas e das lutas sociais. Evidenciou-se o caráter regressivo do ideário pós-moderno e a necessidade de uma teoria para compreender a realidade e superar o modo de produção capitalista.
O patriarcado do salário: notas sobre Marx, gênero e feminismo [Silvia Federici]
Authors: Cury de Rezende Bastos Lilean
Published: January 2023

Resenha do livro O patriarcado do salário: notas sobre Marx, gênero e feminismo, de Silvia Federici.
A agenda pós-moderna na educação e o trabalho docente
Authors: Silva Amanda Moreira da
Published: January 2023

A revista Germinal convidou, neste número, a professora Amanda Moreira da Silva para, de forma conjunta com os leitores, compartilhar reflexões acerca do espraiamento e a capilarização nas últimas décadas da agenda pós-moderna no campo da educação.  A professora Amanda Moreira, inquieta estudiosa, vem pesquisando de forma atenta os recentes movimentos do Capital e, por conseguinte, suas reconfigurações no mundo do trabalho, mais especificamente, sobre o trabalho docente. Nossa entrevistada é professora no Programa de Pós-graduação em Educação da Universidade Federal Rural do Rio de Janeiro (UFRRJ), da Universidade do Estado do Rio de Janeiro (UERJ) junto ao Instituto de Aplicação Fernando Rodrigues da Silveira (CAp-UERJ) e entre suas obras, destacamos: "Tempo e Docência: dilemas, valores e usos na realidade educacional" (2017), "Formas e tendências de precarização do trabalho docente: o precariado professoral e o professorado estável-formal nas redes públicas brasileiras" (2020) e "Trabalho docente sob a lógica privatista empresarial: a busca pela força de trabalho a serviço de um projeto hegemônico" (2021). A revista Germinal agradece à professora Amanda Moreira da Silva pela generosidade de ter aceitado o convite e, sobretudo, pelas essenciais e rigorosas contribuições que foram apresentadas na seguinte entrevista.
Comorbidities of Keloid and Hypertrophic Scars Among Participants in UK Biobank
Authors: Ung Chuin Y. , Warwick Alasdair , Onoufriadis Alexandros , Barker Jonathan N. , Parsons Maddy , McGrath John A. , Shaw Tanya J. , Dand Nick
Published: January 2023

Importance

Keloids and hypertrophic scars (excessive scarring) are relatively understudied disfiguring chronic skin conditions with high treatment resistance.

Objective

To evaluate established comorbidities of excessive scarring in European individuals, with comparisons across ethnic groups, and to identify novel comorbidities via a phenome-wide association study (PheWAS).

Design, Setting, and Participants

This multicenter cross-sectional population-based cohort study used UK Biobank (UKB) data and fitted logistic regression models for testing associations between excessive scarring and a variety of outcomes, including previously studied comorbidities and 1518 systematically defined disease categories. Additional modeling was performed within subgroups of participants defined by self-reported ethnicity (as defined in UK Biobank). Of 502 701 UKB participants, analyses were restricted to 230078 individuals with linked primary care records.

Exposures

Keloid or hypertrophic scar diagnoses.

Main Outcomes and Measures

Previously studied disease associations (hypertension, uterine leiomyoma, vitamin D deficiency, atopic eczema) and phenotypes defined in the PheWAS Catalog.

Results

Of the 972 people with excessive scarring, there was a higher proportion of female participants compared with the 229 106 controls (65% vs 55%) and a lower proportion of White ethnicity (86% vs 95%); mean (SD) age of the total cohort was 64 (8) years. Associations were identified with hypertension and atopic eczema in models accounting for age, sex, and ethnicity, and the association with atopic eczema (odds ratio [OR], 1.68; 95% CI, 1.36-2.07; P < .001) remained statistically significant after accounting for additional potential confounders. Fully adjusted analyses within ethnic groups revealed associations with hypertension in Black participants (OR, 2.05; 95% CI, 1.13-3.72; P = .02) and with vitamin D deficiency in Asian participants (OR, 2.24; 95% CI, 1.26-3.97; P = .006). The association with uterine leiomyoma was borderline significant in Black women (OR, 1.93; 95% CI, 1.00-3.71; P = .05), whereas the association with atopic eczema was significant in White participants (OR, 1.68; 95% CI, 1.34-2.12; P < .001) and showed a similar trend in Asian (OR, 2.17; 95% CI, 1.01-4.67; P = .048) and Black participants (OR, 1.89; 95% CI, 0.83-4.28; P = .13). The PheWAS identified 110 significant associations across disease systems; of the nondermatological, musculoskeletal disease and pain symptoms were prominent.

Conclusions and Relevance

This cross-sectional study validated comorbidities of excessive scarring in UKB with comprehensive coverage of health outcomes. It also documented additional phenome-wide associations that will serve as a reference for future studies to investigate common underlying pathophysiologic mechanisms.
Generalized, Linear Hyperkeratotic Papules With Numerous White Spicules and Comedo-like Plugs
Authors: Chen Tian , Ma Dong-Lai
Published: January 2023

A school-aged boy presents with generalized, linear hyperkeratotic papules with numerous central small filiform keratotic white spicules and brown plugs on the head, face, neck, trunk, and bilateral upper and lower extremities. What is your diagnosis?