bluuebunny/crossref_metadata_2025 huggingface dataset:
Resenha/Book Review: Music Education in an Age of Virtuality and Post-Truth
Authors:   UDESC, Ogibowski Brunno Rossetti
Published: January 2020

Este texto apresenta a resenha do livro Music education in an age of virtuality and post-truth, do professor canadense da Western University, Paul G. Woodford. O livro costura o pragmatismo de John Dewey com as ideias de George Orwell sobre as sociedades de massa em busca de compreender o impacto que determinadas ações de políticos do século XXI podem causar no campo da Educação, da Arte e das Humanidades. Como conclusão, são oferecidos exemplos similares de políticos do Brasil e da América Latina, com o suporte das ideias de Newton Duarte,2 que ele chamou de O currículo em tempos de obscurantismo beligerante (2018).
Canção do Poeta do Século XVIII, de Heitor Villa-Lobos: identidade transitiva no repertório villalobiano para canto e violão
Authors:   Universidade Federal do Rio de Janeiro (UFRJ), Amorim Humberto
Published: January 2020

A partir do levantamento de dados, datas de estreias, entrevistas, primeiras interpretações, gravações e críticas, além de mais de 30 matérias suscitadas em jornais e periódicos, este artigo apresenta dois propósitos: primeiro, realizar uma genealogia das três versões concebidas por Villa-Lobos para uma de suas peças vocais ainda pouco conhecida, a “Canção do Poeta do Século XVIII”; depois, avaliar se (e em que medida) o debate em torno de questões estéticas e/ou estilísticas esteve presente já nos primeiros registros (gravações e performances) e críticas musicais que a obra recebeu ao longo das décadas de 1960 e 1970. Os resultados suscitam um possível olhar sobre a produção para canto e violão de Villa-Lobos a partir do conceito de “identidade transitiva”, proposto por Llanos (2018).
Posthumano y Filosofía del Derecho. Una mirada crítica a la teoría de Rosi Braidotti
Authors: Aparicio Chofré Lucía
Published: January 2020

El presente artículo presenta una visión crítica de la contribución de la filósofa Rosi Braidotti en la elaboración de algunos de los conceptos filosóficos contemporáneos, en especial de sus conceptos de identidades nómadas y del concepto de posthumano. Una teoría en la se reivindica la necesidad de una responsabilidad “posthumana” en la que resulta relevante la aportación de la filosofía del derecho a cuestiones tan actuales como son el reconocimiento de derechos de los animales, el control masivo de personas a través de la vigilancia electrónica o la modificación de la identidad sexual en adolescentes.
Participación ciudadana e inmigración: consideraciones políticas y jurídicas
Authors: Castellanos Claramunt Jorge
Published: January 2020

RESUMEN.  La participación ciudadana es el elemento clave en la labor de integración de las personas migrantes. La perspectiva política y la jurídica de esta cuestión se estudian en el presente trabajo para concluir que el derecho humano a la participación ciudadana es la base sobre la que edificar las democracias del siglo XXI, que no podrán mantener la estructura de ciudadanías de dos velocidades que forman su sociedad. La integración ha de ser lo más completa posible, y ello implica un mayor reconocimiento de derechos a los migrantes, fundamentalmente en el escenario de la participación ciudadana.
Índice de autores/as y estadísticas del número
Authors: Editorial CEFD Gestión
Published: January 2020

Índice de autores/as y estadísticas del número
La creación audiovisual en la infancia. Estudio de experiencias en contextos educativos
Authors: Augustowsky Gabriela Paula
Published: January 2020

Este trabajo aborda la creación audiovisual en la infancia como práctica educativa en el contexto contemporáneo de expansión de propuestas.
Presenta el desarrollo y los resultados de una investigación que estudia sistemáticamente programas y proyectos de enseñanza audiovisual en España y Argentina; se analizan sus encuadres institucionales, propósitos, contenidos, estrategias didácticas, educadores y las creaciones de los niños y niñas. La didáctica audiovisual se postula como un campo de conocimiento en pleno proceso de construcción en el que se conjugan saberes y habilidades provenientes de diferentes disciplinas y con dispar estatus epistemológico. Por último, se enuncian algunos apuntes didácticos entendidos como faros para el desarrollo de nuevas experiencias e investigaciones.
La mirada como acto político. El cine y otros audiovisuales como herramientas educativas de (re)construcción del mundo
Authors: Escaño Carlos
Published: January 2020

El presente artículo propone una reflexión sobre la mirada y lo visual como constituyentes y constructores de realidad cultural. Un estudio articulado a través del análisis cultural de ideas y conceptos claves como método de reflexión. La construcción de la realidad siempre ha sido un hecho político dirigido por los poderes fácticos, pero al entrar en juego, desde el siglo pasado, el potencial de la creación audiovisual y digital para generar mundos posibles, la situación ha mutado hacia un contexto donde la creación y colonización de mundos visuales (y por lo tanto, reales) es prioritaria para las estrategias políticas. Se propone tal fenómeno cultural como un hecho eminentemente ideológico: la mirada cobra una especial relevancia en un cosmos mediado por la imagen, el audiovisual, lo digital, a través de sus dispositivos. El mirar (el mundo), más que nunca, es un hecho político; la producción de imágenes generadas a través múltiples dispositivos se erige como el principal acto en la construcción de la mirada personal y colectiva. La construcción de imágenes depende de esa maquinaria (ideológica) de dispositivos e instrumentos dispuesta para su configuración, la política de generación de imágenes y la usabilidad de tales dispositivos, así como la producción icónica en sí. La mirada y su construcción mantienen profundas implicaciones pedagógicas, donde la imagen en movimiento deviene en poderoso instrumento de transformación educativa y, por extensión, social.
Arte, género y educación: diálogo en Brasil con Everson Melquiades, Vitória Amaral y Fabio Rodrigues
Authors: Huerta Ricard
Published: January 2020

Esta entrevista ha sido posible gracias a la celebración en Brasil del “II Seminário Internacional Arte/Gênero/Ensino em tempos de conservadorismo”. El Seminario tuvo lugar en el Centro de Artes de la URCA Universidad Regional do Cariri, ubicado en la ciudad de Crato (Ceará). Se trata de un evento único en Latinoamérica, por su especificidad. El formato del Seminario resulta muy atractivo y completo, ya que a lo largo de cinco días (del 12 al 16 de agosto de 2019) tienen lugar muchas actividades tanto académicas como de creación artística, lo cual permite asistir a conferencias plenarias, mesas redondas, sesiones de comunicaciones, pero también a piezas teatrales, espectáculos de danza, performances artísticas en diferentes lugares de la ciudad, exposiciones de artes visuales, y un sinfín de actividades más.
Educación a través del arte en Primaria: una necesidad
Authors: Soto Maria Dolores
Published: January 2020

Reseña del libro:
Arte para primaria
Ricard Huerta
Año: 2019 Lugar: Barcelona (España)
Editorial: UOC
Páginas: 189
ISBN: 978-84-9180-552-6
Estudio arqueológico y arqueométrico de restos de cosméticos hallados en una píxide malacológica en Augusta Emerita (Mérida, Badajoz)
Authors: Bajarano Osorio Ana M. , Bustamante Macarena , Navarro Gascón José V. , Marras Susanna , Arteaga Rodríguez Ángela
Published: January 2020

En el presente artículo se da a conocer un hallazgo excepcional localizado en una de las áreas funerarias de la antigua capital de la Lusitania, Augusta Emerita. Concretamente se analizan funcional, tipológica y arqueométricamente una pixide malacológica que contenía durante el momento de su exhumación restos de su contenido. Además se aprovecha la ocasión para realizar un análisis contextual del hallazgo y se pone en relación con el fenómeno del cuidado femenino en época romana
Attacks on genetic privacy via uploads to genealogical databases
Authors: Edge Michael D , Coop Graham
Published: January 2020

Direct-to-consumer (DTC) genetics services are increasingly popular, with tens of millions of customers. Several DTC genealogy services allow users to upload genetic data to search for relatives, identified as people with genomes that share identical by state (IBS) regions. Here, we describe methods by which an adversary can learn database genotypes by uploading multiple datasets. For example, an adversary who uploads approximately 900 genomes could recover at least one allele at SNP sites across up to 82% of the genome of a median person of European ancestries. In databases that detect IBS segments using unphased genotypes, approximately 100 falsified uploads can reveal enough genetic information to allow genome-wide genetic imputation. We provide a proof-of-concept demonstration in the GEDmatch database, and we suggest countermeasures that will prevent the exploits we describe.
Cardiovascular Risk Factors in Nurses Teachers
Authors: Melo Sardinha Daniele , Ignácio da Silva Ana Gracinda , Gouveia Gomes Sandra , Carvalho Pamplona Fabricia , Dos Santos Gorayeb Adriana Letícia , Damous Castanho Ferreira Milena Farah , Socorro Bastos de Carvalho Milene do , Dias Garcez Juliana Conceição
Published: January 2020

Background: Cardiovascular diseases are the main cause of death in Brazil and worldwide, being influenced by the presence of risk factors. In the current life context, these factors are increasingly present in individuals, also related to occupation, which require extensive workload, performance, reasoning, goal plan and maximum dedication from the individual, as is the case of undergraduate teachers in Brazil.

Objective: To identify cardiovascular risk factors in teaching nurses of a private higher education institution (HEI) in Belém, PA, Brazil.

Study Design: A cross-sectional, descriptive survey study with a quantitative approach. At a private HEI in Belém-PA, in March and April 2019.

Methodology: Performed with 11 teachers nurses that the HEI had. A form was used on the teacher's profile and risk factors. Data were analyzed by simple descriptive statistics through the Bioestat 5.0 program.

Results: They are young adults, married, with an extensive workload; 45.45% of them have already had alterations in the HDL and LDL levels, with a family history of Systemic Arterial Hypertension 72.73% and Diabetes Mellitus 81.82%. 45.45% use oral contraceptives. They have a low-fiber diet, rich in lipids and sodium, and practice physical activity. 72.73% consume alcoholic beverages, and none are smokers.

Conclusion: The teaching profession, due to extensive workload and stressful activities, offers a risk for inadequate nutrition, sedentary lifestyle, and lack of time for leisure. These factors are associated with other existing factors, which may increase the chances of cardiovascular diseases in these professionals.
Raw Material from Nutmeg (Myristica fragrans) as Effective Fungicide against Fusarium oxysporum and the Oleoresin Profile of Nutmeg
Authors: Y. L. Fernando A. , S. M. Senevirathne W.
Published: January 2020

Aims: Present study tested the antifungal activity of methanol, ethanol, acetone, chloroform and hot water extracts of nutmeg leaf, mace, kernel and pericarp at three concentration levels (5, 10 and 20%) against Fusarium oxysporum.

Methodology: The agar dilution technique was used and the effect of different concentration of plant extracts on radial growth of reference fungi was evaluated. GC-MS analysis was used for compound analysis.

Results: Complete inhibition of F. oxyporum was found at 10% and 20% concentrations of acetone, ethanol and methanol extracts of leaf, mace, and kernel and, chloroform leaf extract. Mace showed the highest inhibition among sample extracts under every solvent. Among the detected compounds, 3-acridinamine was detected from the genus Myristica for the first time in this study.

Conclusion: The results showed possible use of M. fragrance against F. oxysporum. Since the mace part was rich with many antifungal compounds such as phthalide, palmitic and oleic acid, myristicin, safrol, α-cubebene and aromandendrene, mace can be used as raw material to develop fungicide against F. oxysporum.
Driving Ability and Safety in Rheumatoid Arthritis: A Systematic Review
Authors: Zhou Daniel J. , Mikuls Ted R. , Schmidt Cynthia , England Bryant R. , Bergman Debra A. , Rizzo Matthew , Merickel Jennifer , Michaud Kaleb
Published: January 2020

Objective

To identify whether rheumatoid arthritis (RA) is associated with driving ability and/or the use of assistive devices or modifications to improve driving ability.

Methods

We conducted a systematic literature review following Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines of RA and driving ability/adaptations by searching multiple databases from inception to April 2018. Eligible studies were original articles in the English language that had quantitative data regarding the study objective and at least 5 RA patients. Similar outcomes were extracted across studies and grouped into categories for review.

Results

Our search yielded 1,935 potential reports, of which 22 fulfilled eligibility criteria, totaling 6,285 RA patients. The prevalence of driving issues in RA was highly variable among the studies. Some of the shared themes addressed in these publications included RA in association with rates of motor vehicle crashes, self‐reported driving difficulty, inability to drive, use of driving adaptations, use of assistance by other people for transport, and difficulty with general transportation.

Conclusion

Despite variability among individual reports, driving difficulties and the use of driving adaptations are relatively common in individuals with RA. Given the central importance of automobile driving for the quality of life of RA patients, further investigations of driving ability and potential driving adaptations that can help overcome barriers to safe driving are needed.
Bathless Inorganic Composite Nickel Plating: Dry‐Cell Stamping of Large Hygroscopic Phosphor Crystals
Authors: Gerwitz Caitlyn N. , David Haley M. , Yan Yifan , Shaw Jason P. , Townsend Troy K.
Published: January 2020

In contrast to current composite‐metal electroplating, where objects are submerged into a liquid bath, a bathless aqueous inorganic electroplating method is investigated to increase composite loading and incorporation of large hygroscopic particles. This method can be applied as a stamping coating onto large or irregular conductive objects without the need for an electrolyte bath. Instead of stirring in solution, the composite particles are trapped in the electrolyte and forced to plate within the metal matrix. In this set‐up, a nickel salt mixture containing the composite is applied to the cathode and is separated from the anode with an ion‐permeable membrane. As a proof of concept, large noncharged fluorescent composite particles are electrochemically embedded via electrochemical reduction of nickel salts resulting in up to 80 ± 12% surface area coverage after controlling deposition parameters of current density and duration. Long persistent afterglow SrAl2O4:Eu2+, Dy3+ phosphor powder is chosen because of its large crystal size (87 ± 30 µm) and hygroscopic nature. The photoluminescent quantum yield is measured and compared to the composite coatings, which reaches up to 9.9 ± 0.8% after 18 h of coating. Film morphology, phosphor surface loading, and film thickness are characterized by optical microscopy.
Shrinkage of Cholesteric Liquid Crystalline Microcapsule as Omnidirectional Cavity to Suppress Optical Loss
Authors: Iwai Yosuke , Iijima Ryosuke , Yamamoto Kaho , Akita Takuya , Uchida Yoshiaki , Nishiyama Norikazu
Published: January 2020

Cholesteric liquid crystalline (CLC) emulsions are the easiest 3D omnidirectional laser resonators to fabricate. To exploit the full potential of CLC emulsions as distributed Bragg reflection (DBR) mode laser resonators, monodispersed water‐in‐CLC‐in‐water double emulsions (CLC microcapsules) have higher performance scalability than simple CLC droplets. If laser dyes are concentrated at the center of CLC microcapsules, emitted light from the dye is 3D confined. When water is squeezed from the inner phase of a CLC microcapsule comprising an aqueous laser dye solution by means of osmotic pressure difference from the outer phase, the DBR lasing threshold of the CLC microcapsule is reduced. The shrinkage of the inner droplet contributes not only the simple reduction of the cavity length but also the suppression of the optical loss to reduce the lasing threshold. The reduced optical loss is beneficial to realize various devices: optical manipulation, photonic cross communications, and biochemical, light, and temperature sensing. Their flexible photonic structures are suitable for emerging and future optical devices like wearable optical devices.
Preparation of Scalable Silica‐Coated Iron Oxide Nanoparticles for Nanowarming
Authors: Gao Zhe , Ring Hattie L. , Sharma Anirudh , Namsrai Baterdene , Tran Nam , Finger Erik B. , Garwood Michael , Haynes Christy L. , Bischof John C.
Published: January 2020

Cryopreservation technology allows long‐term banking of biological systems. However, a major challenge to cryopreserving organs remains in the rewarming of large volumes (>3 mL), where mechanical stress and ice formation during convective warming cause severe damage. Nanowarming technology presents a promising solution to rewarm organs rapidly and uniformly via inductive heating of magnetic nanoparticles (IONPs) preloaded by perfusion into the organ vasculature. This use requires the IONPs to be produced at scale, heat quickly, be nontoxic, remain stable in cryoprotective agents (CPAs), and be washed out easily after nanowarming. Nanowarming of cells and blood vessels using a mesoporous silica‐coated iron oxide nanoparticle (msIONP) in VS55, a common CPA, has been previously demonstrated. However, production of msIONPs is a lengthy, multistep process and provides only mg Fe per batch. Here, a new microporous silica‐coated iron oxide nanoparticle (sIONP) that can be produced in as little as 1 d while scaling up to 1.4 g Fe per batch is presented. sIONP high heating, biocompatibility, and stability in VS55 is also verified, and the ability to perfusion load and washout sIONPs from a rat kidney as evidenced by advanced imaging and ICP‐OES is demonstrated.
Wheat growth and grain yield responses to sowing date‐associated variations in weather conditions
Authors: Zhou Baoyuan , Sun Xuefang , Ge Junzhu , Li Congfeng , Ding Zaisong , Ma Shaokang , Ma Wei , Zhao Ming
Published: January 2020

Variations in weather conditions can affect winter wheat (Triticum aestivum L.) yield. This study aimed to determine the ways in which the yield formation processes of winter wheat respond to variations in weather conditions at a large range. Five sowing dates (SDs) were set at 15‐d intervals from early October to early December during the period 2015–2017 in the North China Plain (NCP). Sowing in mid‐October (SD2) produced the highest yield, which was similar to that of conventional sowing (early October, SD1). Sowing in early December (SD5) increased wheat yields by 6.1 and 14.0% averaged two year compared to sowing in early (SD3) or late (SD4) November, respectively. The increased yield for SD5 was attributed to increased dry matter accumulation (DMA) pre‐anthesis, and greater numbers of spikes and kernels. The DMA, spike number, and kernel number were mainly influenced by the pre‐anthesis plant growth rate (PGR), which was affected by temperature from sowing to anthesis. Low temperatures (maximum temperature <18.9°C, minimum temperature <7.6°C, daily mean temperature <12.8°C) from sowing to anthesis occurred following SD3 and SD4 sowings, which decreased pre‐anthesis PGR, and in turn decreased the pre‐anthesis DMA and spike and kernel number. These eventually reducing the total biomass and grain yield. We conclude that sowing wheat extremely late (early December) has the potential to increase grain yield, which may offset the negative effects of climatic factors in the NCP.
Cobalt‐katalysierte Kreuzkupplung funktionalisierter Alkylzinkreagenzien mit (Hetero‐)Arylhalogeniden
Authors: Lutter Ferdinand H. , Grokenberger Lucie , Spieß Philipp , Hammann Jeffrey M. , Karaghiosoff Konstantin , Knochel Paul
Published: January 2020

Eine Kombination aus 10 % CoCl2 und 20 % 2,2′‐Bipyridin als Liganden ermöglicht die Kreuzkupplung von funktionalisierten primären und sekundären Alkylzinkreagenzien mit diversen (Hetero‐)Arylhalogeniden. Die Kupplung mit 1,3‐ und 1,4‐substituierten Cycloalkylzinkreagenzien erzeugte funktionalisierte Heterocyclen in hohen Diastereoselektivitäten von bis zu 98:2. Des Weiteren ließen sich Alkinylbromide mit primären und sekundären Zinkreagenzien zu alkylierten Alkinen umsetzen.
Distal Allylic/Benzylic C−H Functionalization of Silyl Ethers Using Donor/Acceptor Rhodium(II) Carbenes
Authors: Vaitla Janakiram , Boni Yannick T. , Davies Huw M. L.
Published: January 2020

Regio‐ and stereoselective distal allylic/benzylic C−H functionalization of allyl and benzyl silyl ethers was achieved using rhodium(II) carbenes derived from N‐sulfonyltriazoles and aryldiazoacetates as carbene precursors. The bulky rhodium carbenes led to highly site‐selective functionalization of less activated allylic and benzylic C−H bonds even in the presence of electronically preferred C−H bonds located α to oxygen. The dirhodium catalyst Rh2(S‐NTTL)4 is the most effective chiral catalyst for triazole‐derived carbene transformations, whereas Rh2(S‐TPPTTL)4 works best for carbenes derived from aryldiazoacetates. The reactions afford a variety of δ‐functionalized allyl silyl ethers with high diastereo‐ and enantioselectivity. The utility of the present method was demonstrated by its application to the synthesis of a 3,4‐disubstituted l‐proline scaffold.
Rhodium‐Catalyzed Enantioselective [4+2] Cycloadditions of Vinylcarbenes with Dienes
Authors: Zhang Bowen , Davies Huw M. L.
Published: January 2020

The reaction of 2‐siloxycyclo‐1,3‐dienes with E‐vinyldiazoacetates in the presence of the bulky chiral dirhodium tetracarboxylate catalyst, Rh2(R‐p‐PhTPCP)4 results in an enantioselective [4+2] cycloaddition, in which three new stereogenic centers are formed. The [4+2] cycloadducts are generated as single diastereomers with high enantiocontrol (95–98 % ee). When the diene contains an additional stereogenic center, effective kinetic resolution can be achieved.
Cobalt(II) and silver(I) coordination polymers containing flexible bis (benzimidazol‐1‐yl)hexane ligands: synthesis, crystal structures, sensing and photocatalytic properties
Authors: Li Ai‐Ling , Hao Zeng‐Chuan , Han Chao , Cui Guang‐Hua
Published: January 2020

Two new ternary metal coordination polymers (CPs), namely, {[Co2(BTC)(L)]·0.25H2O}n (1) and [Ag(HIPA)(L)]n (2) (H4BTC = 1,2,3,4‐butanetetracarboxylic acid, H2IPA = isophthalic acid, L = 1,6‐bis(5,6‐dimethylbenzimidazol‐1‐yl)hexane) were hydrothermally synthesized and characterized by elemental analysis, infrared spectroscopy, single‐crystal X‐ray diffraction, and powder X‐ray diffraction (PXRD). 1 exhibits unusual 2D network with point symbol {43.63}2{46.66.73}. 2 possesses 1D chain structure which is further extended into a 3D supramolecular network via O–H···O hydrogen‐bonding and π–π stacking interactions. 1 and 2 can selectively detect benzaldehyde (BZH), Fe3+ (just 1) and Cr2O72− (just 2) ions in water via the luminescence quenching process. Furthermore, the photocatalytic activities of two CPs were evaluated for degradation of methylene blue (MB) and methyl violet (MV) under UV irradiation.
Optical and electrical properties and conduction mechanism of [(CH3)2NH2]2CoCl4
Authors: Mahfoudh N. , Karoui K. , Gargouri M. , BenRhaiem A.
Published: January 2020

Monoclinic crystals of [(CH3)2NH2]2CoCl4 are of the space group P21/n. Unit cell dimensions are as follows: a = 8.5393 Å, b = 11.3905 Å, c = 13.4069 Å and β = 91.02°. This compound undergoes several phase transitions. The optical properties were measured by means of UV–visible absorption spectroscopy in the range 200–800 nm. Analysis of the data revealed the existence of direct allowed optical transition mechanisms with bandgap energy equal to 3.84 eV. The electrical conductivity of [(CH3)2NH2]2CoCl4 was studied in the frequency range 10−1–106 Hz and in the temperature range 411–449 K by means of impedance spectroscopy. Impedance and modulus analyses indicated temperature‐independent distribution of relaxation times and non‐Debye behavior in this material. A super‐linear power law was observed for the AC conductivity, which was analyzed based on the jump relaxation model σac = σdc + A1ωs1 + A2ωs2. Accordingly, the first AC term A1ωs1 corresponds to translational hopping motion and the second term A2ωs2 to well‐localized hopping and/or reorientational motion. Conduction takes place via correlated barrier hopping in phases I and II.
Cu2+ sensing via noncovalent complexes of fluorescent whitening agents and imidazole‐based polymeric dye transfer inhibitors
Authors: Fernandes Gregory Edward , Ugwu Chidera
Published: January 2020

Fluorescent whitening agents (FWAs) and polymeric dye transfer inhibitors (DTIs) are widely used in detergent formulations to combat garment yellowing, fading, and discoloration. We report a new application for these inexpensive, mass‐produced, laundry additives as sensitive fluorescence “turn‐off” sensors for Cu2+. We show that Cu2+‐sensitive FWA–DTI complexes form spontaneously when aqueous solutions of FWA and imidazole‐based DTI are mixed. We also show that the imidazole groups present in the resulting fluorescent FWA–DTI complex selectively bind Cu2+, a potent fluorescence quencher, to form nonfluorescent FWA–DTI‐Cu2+ complexes. Our Cu2+‐sensing FWA–DTI complexes are completely water‐soluble and have a Cu2+ detection limit of ~ 0.14 μM in water. Our simple approach not only converts the Cu2+‐insensitive FWAs into sensitive fluorescent probes for the metal ion but also significantly enhances the brightness of triazinylaminostilbene FWAs. The present study provides a facile, synthesis‐free strategy for producing inexpensive fluorescent sensors for Cu2+. © 2020 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48915.
Effects of electrophoretic deposition process parameters on the mechanical properties of graphene carboxyl‐grafted carbon fiber reinforced polymer composite
Authors: Yandrapu Sagar , Gangineni Pavan K. , Ramamoorthy Sunil K. , Ray Bankim C. , Prusty Rajesh K.
Published: January 2020

Carbon fiber (CF) modification by grafting of various graphene‐based nanofillers (GBN) by electrophoretic deposition (EPD) technique was proven to be a successful technique to enhance the out‐of‐plane performance of carbon fiber reinforced polymer (CFRP) composites. Graphene carboxyl (G‐COOH) grafting on carbon fiber by electrophoretic deposition (EPD) is a promising technique to improve the mechanical properties of CFRP composites. To our knowledge, there is a dearth of literature available on the effect of EPD process parameters on the mechanical behavior of modified CFRP composites. The aim of this study is to evaluate the effect of nanofiller concentration in the suspension, applied current, and the time of deposition during EPD on the mechanical behavior of nanophase CFRP composites, thus making it a novel work. With increasing concentration, interlaminar shear strength (ILSS) improved consistently and has shown a maximum enhancement of 24.7% than that of neat CFRP composite at 1.5 g/L nanofiller concentration, whereas flexural strength remained almost unaffected with varying concentration. On the contrary, variation of deposition current has affected the flexural strength but not ILSS. The maximum flexural strength was obtained at a deposition current of 5.0A with an improvement of 16.3% in comparison with neat CFRP samples. However, both flexural strength and ILSS of hybrid CFRP composites have shown improvement with increasing deposition time. At 60 min of deposition, ILSS and flexural strength have shown maximum improvements of 35.0 and 26.6%, respectively, when compared to control specimen. After evaluating the effect of process parameters future scope of the work involves the optimization of parameters for EPD of G‐COOH. Fractographic analysis of the fractured samples was performed using scanning electron microscope (SEM) to apprehend prominent failure mechanisms. © 2020 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48925.
Preparation of sulfonated polysulfone/sulfonated titanium dioxide hybrid membranes for DMFC applications
Authors: Zhang Xinxin , Xia Yifan , Gong Xinjian , Geng Pengfei , Gao Zhenwei , Wang Yinghan
Published: January 2020

Sulfonated titanium dioxide (STiO2) was prepared by the reaction of TiO2 with 1,3‐propanesultone. Novel STiO2 incorporated sulfonated poly(aryl ether sulfone) (SPAES) nanocomposite proton exchange membranes (PEMs) were made by solution casting. Fourier transform infrared, X‐ray photoelectron spectroscopy, and proton nuclear magnetic resonance indicated the successful preparation of STiO2 and SPAES. The thermogravimetric analysis and oxidative stability testing results implied that SPAES/STiO2 membranes had better stability than pristine SPAES membrane. Meanwhile, the scanning electron microscopy spectra exhibited that the introduction of sulfonated groups on the surface of TiO2 significantly improved its dispersibility in SPAES matrix. More specifically, SPAES membrane incorporated with 2%STiO2 exhibited higher proton conductivity (60 mS cm−1), lower methanol permeability (2.1 × 10−7 cm2 s−1) and better proton selectivity (28.0 × 104 S s cm−3) than that of pure SPAES and SPAES/1%TiO2 membrane. The SPAES‐1%STiO2 membrane showed better performance in direct methanol fuel cell (DMFC) test than SPAES and Nafion 117 due to the reduction of methanol crossover. From these results, it is evident that SPAES/STiO2 nanocomposite PEMs have great potential for applications in DMFCs. © 2020 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48938.
Serum proteins TGFBI, PCSK9, and CCL14 are potential biomarkers for different traditional Chinese medicine syndromes of multidrug‐resistant tuberculosis
Authors: Hu Yu‐Ting , Yi Wen‐Jing , Jiang Ting‐Ting , Tu Hui‐Hui , Wei Li‐Liang , Shi Li‐Ying , Liu Chang‐Ming , Chen Jing , Han Yu‐Shuai , Gan Lin , Li Zhi‐Bin , Huang Huai , Li Ji‐Cheng
Published: January 2020

Patients with multidrug‐resistant tuberculosis (MDR‐TB) tend to have a long course of anti‐TB treatment and severe side effects. Traditional Chinese Medicine (TCM) has a synergistic effect in attenuation of MDR‐TB. However, the lack of objective biological standards to classify and diagnose MDR‐TB TCM syndromes could result in less effective TCM treatment. Therefore, in this study, we identified differentially expressed proteins (DEPs) in serum of individuals with MDR‐TB TCM syndromes by applying isobaric tags for relative and absolute quantification coupled with two‐dimensional liquid chromatography–tandem mass spectrometry (iTRAQ‐2DLC–MS/MS) method and bioinformatics analysis. The functional analysis of DEPs was also performed. Additionally, DEPs among three different TCM syndromes of MDR‐TB were validated by enzyme‐linked immunosorbent assay (ELISA). Finally, a receiver operating characteristic (ROC) curve was performed to estimate the diagnostic ability of DEPs. A total of 71 DEPs were identified in the three different MDR‐TB TCM syndrome groups such as the pulmonary Yin deficiency (PYD) syndrome group, the Hyperactivity of Fire due to Yin deficiency (HFYD) syndrome group, and the deficiency of Qi and Yin (DQY) syndrome group. The results showed that the expression level of transforming growth factor‐beta‐induced protein ig‐h3 (TGFBI) was lower in the PYD syndrome group (p = .002), the proprotein convertase subtilisin/kexin type 9 (PCSK9) was overexpressed in the HFYD syndrome group (p < .0001), and the C–C motif chemokine ligand 14 (CCL14) expression level was reduced in the DQY syndrome group (p = .004). Our study demonstrated that serum TGFBI, PCSK9, and CCL14 may serve as potential novel biomarkers for PYD syndrome, HFYD syndrome and DQY syndrome of MDR‐TB, respectively. The study provides a biological basis for MDR‐TB TCM syndromes classification and can be of great significance for the treatment of different TCM syndromes.
Static universe model existing due to the matter‐dark energy coupling
Authors: Cabo Bizet Alejndro , Cabo Montes de Oca Alejandro
Published: January 2020

The work investigates a static, isotropic, and almost homogeneous Universe containing a real scalar field modeling the dark energy (DE) (quintessence) interacting with pressureless matter. It is argued that the interaction between matter and the DE is essential for the very existence of the considered solution. Assuming the possibility that DE can be furnished by the Dilaton (a scalar field reflecting the condensation of string states with zero angular momentum), we fix the value of scalar field at the origin to the Planck scale. It became possible to fix the ratio of the amount of DE to matter energy, in the currently estimated value and also the observed magnitude of the Hubble constant. The mass of the scalar field chosen for fixing the above ratio and Hubble effect strength, results to be of the order of 10−29 cm−1, a small value which seems to be compatible with the zero mass of the Dilaton in the lowest approximations.
Matching one‐loop divergences in 7D Einstein and 6D Conformal Gravities
Authors: Aros Rodrigo , Bugini Fabrizzio , Díaz Danilo E.
Published: January 2020

Within the context of AdS/CFT correspondence, we first compute the one‐loop infrared (IR) divergences of 7D Einstein gravity in a certain Poincaré‐Einstein background metric. Then, we compute the one‐loop ultraviolet (UV) divergences of 6D conformal gravity on the conformal boundary. We verify the equality of the above results that stem from the IR–UV connection of the duality dictionary. Key ingredients are heat kernel techniques, factorization of the boundary higher‐derivative kinetic operator for the Weyl graviton on the 6D Einstein metric, and Wentzel–Kramers–Brillouin (WKB) exactness of the Einstein graviton in the chosen 7D Poincaré‐Einstein background. Overall, we elucidate the way in which the 6D results containing the type‐A and type‐B conformal anomalies for the Weyl graviton are encoded in the 7D “hologram” given by the fluctuation determinant for the Einstein graviton. We finally discuss possible extensions to include higher‐spin fields.
A Magnetic Resonance Spectroscopy Study of Superior Visual Search Abilities in Children with Autism Spectrum Disorder
Authors: Edmondson David A. , Xia Pingyu , McNally Keehn Rebecca , Dydak Ulrike , Keehn Brandon
Published: January 2020

Although diagnosed on the basis of deficits in social communication and interaction, autism spectrum disorder (ASD) is also characterized by superior performance on a variety of visuospatial tasks, including visual search. In neurotypical individuals, region‐specific concentrations of the inhibitory neurotransmitter gamma‐aminobutyric acid (GABA) are associated with individual differences in attention and perception. While it has been hypothesized that ASD may be associated with an excitatory–inhibitory imbalance, it remains unclear how this may contribute to accelerated visual search performance in individuals with ASD. To investigate this, 21 children with ASD and 20 typically developing children participated in a visual search task and a magnetic resonance spectroscopy study to detect neurochemical concentrations, including GABA. Region‐specific neurochemicals were examined in the right frontal eye fields, right temporal–parietal junction (rTPJ), and bilateral visual cortex (VIS). GABA concentrations did not differ between groups; however, in children with ASD, greater GABA concentration in the VIS was related to more efficient search. Additionally, lower VIS GABA levels were also associated with increased social impairment. Finally, we found reduced N‐acetyl aspartate, total creatine, glutamate and glutamine (Glx), GABA/Glx in the rTPJ, suggestive of neuronal dysfunction in a critical network hub. Our results show that GABA concentrations in the VIS are related to efficient search in ASD, thus providing further evidence of enhanced discrimination in ASD. Autism Res 2020, 13: 550–562. © 2019 International Society for Autism Research, Wiley Periodicals, Inc.

Lay Summary

Children with autism spectrum disorder (ASD) often perform better than their non‐ASD peers on visual search tasks; however, it is unclear how they achieve this superior performance. Using magnetic resonance spectroscopy to measure neurochemicals in the brain, we found that the level of one, gamma‐aminobutyric acid, in the visual cortex was directly related to search abilities in children with ASD. These results suggest that faster search may relate to enhanced perceptual functioning in children with ASD.
Tapping enhances vasodilation for venipuncture even in individuals with veins that are relatively difficult to palpate
Authors: Ichimura Mika , Sasaki Shinsuke , Ogino Tetsuya
Published: January 2020

Introduction

This study evaluated whether tapping enhances vasodilation in individuals with veins that are relatively difficult to palpate.

Materials and Methods

Twenty participants (4 men and 16 women, aged 19–22 years) with cutaneous veins that were relatively difficult to palpate even after tourniquet application were recruited. A crossover trial with/without tapping (10 times in 5 s) was performed under tourniquet inflation on the upper arm. Vasodilation was evaluated by venous cross‐sectional area, depth of the vein, and elevation of the overlying skin by ultrasonography. Venous palpation scores were also measured. The degree of improvement was estimated by simulation.

Results

In total, 60% of participants “sometimes” or “often” experienced unsuccessful venipuncture. After the tapping procedure, the venous cross‐sectional area significantly increased (14.6 ± 9.12 mm2 for control and 15.2 ± 9.79 mm2 for tapping) and venous depth significantly decreased (4.57 ± 2.31 mm for control and 4.23 ± 2.41 mm for tapping). A simulation study using these values suggested that tapping increased the longitudinal and crosswise successful ranges of venipuncture by 5–6%.

Conclusions

Tapping in this study enhanced the vasodilation of cutaneous veins that are relatively difficult to palpate. The effectiveness of various vasodilation methods may be compared through the estimation of improvement.
First‐in‐man study of a thinner‐strut sirolimus‐eluting bioresorbable scaffold (FUTURE‐I): Three‐year clinical and imaging outcomes
Authors: Song Lei , Sun Zhongwei , Guan Changdong , Yan Hongbing , Yu Mengyue , Cui Jingang , Mu Chaowei , Qiu Hong , Tang Yida , Zhao Yanyan , Qiao Shubin , Suryapranata Harry , Gao Runlin , Xu Bo ,   for the FUTURE‐I Investigators
Published: January 2020

Objectives

The FUTURE‐I study aimed to assess preliminary safety and effectiveness with the long‐term clinical and imaging follow‐up for the Firesorb (MicroPort, Shanghai, China), a thinner‐strut sirolimus‐eluting bioresorbable scaffold (BRS).

Background

First‐generation BRS has been associated with unexpected device‐related adverse outcomes at long‐term follow‐up.

Methods

In this prospective, open‐label, first‐in‐man study, patients with single de novo lesions in native coronary arteries were randomized 2:1 into two cohorts after successful Firesorb implantation: cohort 1 (n = 30) underwent multimodality imaging assessment at 6 and 24 months; and cohort 2 (n = 15) at 12 and 36 months. All patients underwent clinical follow‐up at 1, 6, and 12 months and annually up to 5 years.

Results

Between January and March 2016, 45 patients were enrolled. At 3‐year follow‐up, one patient had experienced target lesion failure and none scaffold thrombosis. In‐scaffold minimal lumen diameter decreased significantly from 6‐month to 2‐year (2.53 ± 0.24 mm vs. 2.27 ± 0.37 mm, p = .0003), and only numerically from 1‐year to 3‐year follow‐up (2.48 ± 0.28 mm vs. 2.22 ± 0.13 mm, p = .08). By optical coherence tomography, neointimal strut coverage at 3‐year follow‐up was 99.8%, and very low rate of late scaffold discontinuity was observed, only in one patient on two cross sections with three malapposed struts.

Conclusions

At 3‐year follow‐up of the FUTURE‐I study, implantation of the thinner‐strut Firesorb BRS appeared preliminary feasible and effective in the treatment of patients with noncomplex coronary lesions.
Effectiveness of clozapine, oxcarbazepine and rivastigmine combination in a bipolar disorder patient with initial cerebral atrophy
Authors: Morana Paolo , Mucci Federico , Baroni Stefano , Della Vecchia Alessandra , Piccinni Armando , Morana Benedetto , Marazziti Donatella
Published: January 2020

This paper reports the case of a 46‐year‐old woman suffering from bipolar disorder of type I with mixed features with initial fronto‐temporal atrophy. Although considered treatment‐resistant to conventional strategies, she successfully responded to a combination of rivastigmine, clozapine, and oxcarbazepine.
Primary diffuse large B‐cell lymphoma presenting as acute appendicitis: A report of 2 cases and a literature review
Authors: Fernandez Turizo Maria Jose , Kharfan‐Dabaja Mohamed A. , Alhaj Moustafa Muhamad , Ayala Ernesto , Jiang Liuyan , Parrondo Ricardo
Published: January 2020

Primary appendiceal lymphomas (PAL) are a type of primary gastrointestinal non‐Hodgkin lymphoma (PGINHL) with an incidence of <1%. There is considerable discordance with regard to the optimal management of PGINHL. We describe two cases of PAL, perform a literature review, and discuss the available evidence for optimal treatment.
Dual Mechanoenzymatic Kinetic Resolution of (±)‐Ketorolac
Authors: Pérez‐Venegas Mario , Rodríguez‐Treviño Agustín Mario , Juaristi Eusebio
Published: January 2020

Recently, biocatalysis mediated by mechanical energy has become a convenient strategy to obtain highly valuable products following the principles of green chemistry. In particular, mechanoenzymatic techniques have allowed the isolation of chiral drugs with high enantiomeric purity. In this regard, being aware of the preponderant anti‐inflammatory activity of Ketorolac's (S)‐isomer relative to its (R)‐enantiomer, we developed a mechanoenzymatic kinetic resolution protocol using Candida antarctica Lipase B to yield both enantiomers with high enantiopurity. The significant enantiopreference of CALB for the (R)‐isomer of Ketorolac allowed the isolation of the active (S)‐enantiomer, either by means of an enantioselective esterification of racemic Ketorolac or via enantioselective hydrolysis of suitable ester derivatives. Both techniques proceeded in short reaction times, with high enantiomeric excess (>83 %), remarkable enantiodiscrimination (E≫500) and rather good conversion (46 %). Furthermore, (R)‐Ketorolac, an effective drug for ovarian cancer management, was obtained in essentially enantiopure form (ee >99 %).
1H NMR spectroscopy coupled with multivariate analysis was applied to investigate Italian cherry tomatoes metabolic profile
Authors: Masetti Olimpia , Nisini Luigi , Ciampa Alessandra , Dell'Abate Maria Teresa
Published: January 2020

Nuclear magnetic resonance (NMR) spectroscopy, in combination with different chemometric methods, was widely used for metabolomic profiling in the geographical determination of food origin. In the present study, spectra data of cherry tomatoes, collected from Pachino (Sicily) and Sabaudia (Latium), were analyzed by principal component analysis (PCA), k nearest neighbors (kNN), and partial least‐squares discriminant analysis (PLS‐DA) in order to discriminate the samples according to their geographical provenance.

The PCA analysis of 1H NMR spectra of Sabaudia cherry tomatoes showed significant differences linked to the production year: phospholipids had higher levels in 2004, but less amounts of polyunsaturated acids and lycopene were observed with respect to the year 2005. Despite the annual differences in 1H NMR metabolic profile of Sabaudia cherry tomatoes, using unsupervised (PCA) and supervised (PLS‐DA, kNN) approaches, the geographical origin differentiation was obtained. In fact, the kNN algorithm correctly classified approximately 84% to 87% of Pachino samples and 77% of Sabaudia ones with recognition ability varied from 82% to 84.4% and prediction ability (CV) of 76.2% and 94.7%. The PC1 component, with 53% of total variance, greatly separated Pachino cherry tomatoes from Sabaudia ones and PLS‐DA model showed a good degree of separation with recognition ability of 100% and prediction ability (CV) of 93% to 100%.

PCA and PLS‐DA combined analysis highlighted the most prominent spectral areas that well separated the two groups of samples. So, phytosterols were found discriminating compounds according to PCA and PLS‐DA and differences in aroma components were observed mainly in PCA analysis.
Co‐hydrolysis and Seed‐Induced Synthesis of Basic Mesoporous ZSM‐5 Zeolites with Enhanced Catalytic Performance
Authors: Ye Zhaoqi , Zhao Yang , Zhang Hongbin , Zhang Yahong , Tang Yi
Published: January 2020

For zeolite catalysts, the regulation of active site and pore structure plays an important role in the enhancement of their catalytic performance. In this work, a one‐pot and organic template‐free co‐regulation route is proposed to straightforwardly synthesize basic mesoporous ZSM‐5 zeolites with adjustable alkaline‐earth metal species. The synthesis pathway combines two decisive strategies: 1) the seed‐induced interface assembly growth method and 2) the acidic co‐hydrolysis/condensation of aluminosilicate species and alkaline‐earth metal (e.g., Mg, Ca, Sr, or Ba) sources. It is interesting that the mesoporous structure was self‐evolved through particle‐attached seed‐interfacial crystallization without the assistance of any template. Meanwhile, the incorporation of alkaline‐earth metals species is homogeneous and highly dispersed in the solid products during the whole crystallization process, and finally generate the superior basicity. Catalysis tests of the as‐synthesized samples displayed their novel performance in the typical base reaction of Knoevenagel condensation, even for bulky substrates owing to the enhanced diffusion arising from the meso/microporous network. This finding opens new possibilities for facile, cost‐effective, and environmentally friendly synthesis of mesoporous high‐silica zeolites with tunable acid/base properties, and deepens our understanding of the particle‐attached crystallization.
Pressure Sensitivity of SynGAP/PSD‐95 Condensates as a Model for Postsynaptic Densities and Its Biophysical and Neurological Ramifications
Authors: Cinar Hasan , Oliva Rosario , Lin Yi‐Hsuan , Chen Xudong , Zhang Mingjie , Chan Hue Sun , Winter Roland
Published: January 2020

Biomolecular condensates consisting of proteins and nucleic acids can serve critical biological functions, so that some condensates are referred as membraneless organelles. They can also be disease‐causing, if their assembly is misregulated. A major physicochemical basis of the formation of biomolecular condensates is liquid–liquid phase separation (LLPS). In general, LLPS depends on environmental variables, such as temperature and hydrostatic pressure. The effects of pressure on the LLPS of a binary SynGAP/PSD‐95 protein system mimicking postsynaptic densities, which are protein assemblies underneath the plasma membrane of excitatory synapses, were investigated. Quite unexpectedly, the model system LLPS is much more sensitive to pressure than the folded states of typical globular proteins. Phase‐separated droplets of SynGAP/PSD‐95 were found to dissolve into a homogeneous solution already at ten‐to‐hundred bar levels. The pressure sensitivity of SynGAP/PSD‐95 is seen here as a consequence of both pressure‐dependent multivalent interaction strength and void volume effects. Considering that organisms in the deep sea are under pressures up to about 1 kbar, this implies that deep‐sea organisms have to devise means to counteract this high pressure sensitivity of biomolecular condensates to avoid harm. Intriguingly, these findings may shed light on the biophysical underpinning of pressure‐related neurological disorders in terrestrial vertebrates.