bluuebunny/crossref_metadata_2025 huggingface dataset:
Electrically tunable dual-layer twisted nematic liquid crystal THz phase shifters with intermediate composite polymer thin film
Authors: Sahoo Anup Kumar , Lin Yi-Hsin , Yang Chan-Shan , Wada Osamu , Yen Chun-Ling , Pan Ci-Ling
Published: November 2022

We demonstrate electrically tunable twisted nematic (TN) aligned liquid crystal (LC) terahertz phase shifters with a novel structure, in which a single LC composite polymer thin film is inserted in the middle of the LC cell. For designing such types of phase shifters, we have applied the Mauguin formalism used in LC-based switches for applications in the visible. Experimental results are in good agreement with those predicted by the theoretical model. Using this design, the phase shift has been increased by 14.3° at 1.2 THz in comparison to the conventional design (98.1°). The threshold voltage has been lowered from 0.81 VRMS to 0.48 VRMS while the driving voltage for quarter-wave (π/2) phase shift operation has been reduced from 8.4 VRMS to 6.3 VRMS at 1.2 THz. The dynamic response of devices also enhances significantly. Such design has also successfully been adopted to demonstrate a 2π phase shifter with similar improvement. Full-wave operation is achieved at a bias of 25 VRMS at 1.2 THz using a highly birefringent LC material. Order parameter calculations show that the polymer film improves significantly LC molecular alignment in the thick LC cell for THz applications. We have also compared the figure of merits (FOMs) of the present devices with previously reported THz π/2 and 2π phase shifters.
Provider perspectives on emotional health care for adults with type 2 diabetes mellitus in the Dominican Republic
Authors: Wallace Deshira D. , Pereira Nastacia M. , Rodriguez Humberto Gonzalez , Barrington Clare
Published: November 2022

The emotional burden of type 2 diabetes mellitus (T2D) can complicate self-management. Exploring the feasibility of mental and physical health co-management in limited-resourced settings is needed. Thus, we assessed providers’ awareness of the emotional burden their patients experience and their roles in supporting their patients with T2D. We conducted a formative qualitative study using in-depth interviews with 14 providers, including physicians, nurses, and community health workers recruited at two rural health clinics in the Dominican Republic. We coded transcripts using inductive and deductive codes and developed themes through iterative comparative analysis. All providers recognized that patients experience an emotional burden managing life with T2D. Some providers viewed the provision of emotional support as integral to their role and believed that they could do so. Others viewed it as the responsibility of the family or expressed the need for additional guidance on how to provide emotional support. Providers also identified several barriers to integrating emotional support into routine clinical care including personality characteristics, lack of training, and insufficient staffing. While providers recognize the need for emotional support, they identified individual, clinical, and systems-level barriers. Strategies to address these barriers include training specific providers on emotional support provision, balancing workload, and building or strengthening referral systems.
Protocol for iSISTAQUIT: Implementation phase of the supporting indigenous smokers to assist quitting project
Authors: Gould (Judean) Gillian Sandra , Kumar Ratika , Ryan Nicole M. , Stevenson Leah , Oldmeadow Christopher , La Hera Fuentes Gina , Deeming Simon , Hyland (Kamilaroi) Rebecca , Yuke (Yugambeh) Kym , McMillan (Wiradjuri) Faye , Oldenburg Brian , Clarke (Worimi) Marilyn J.
Published: November 2022

Introduction

About 44% of Aboriginal and/or Torres Strait Islander women smoke during pregnancy compared to 12% of their general population counterparts. Evidence-based quit smoking advice received from health care professionals (HCPs) can increase smoking cessation rates. However, HCPs lack culturally appropriate smoking cessation training, which is a major barrier to provision of smoking cessation care for this population.

Methods and analysis

iSISTAQUIT is a multicentre, single arm study aiming to implement and evaluate the evidence-based, culturally competent iSISTAQUIT smoking cessation training among health practitioners who provide support and assistance to pregnant, Aboriginal and Torres Strait Islander women in Australia. This project will implement the iSISTAQUIT intervention in Aboriginal Medical Services and Mainstream Health Services. The proposed sample size is 10 of each of these services (total N = 20), however if the demand is higher, we will aim to accommodate up to 30 services for the training. Participating sites and their HCPs will have the option to choose one of the two iSISTAQUIT packages available: a) Evaluation- research package b) Training package (with or without continued professional development points). Training will be provided via an online eLearning platform that includes videos, text, interactive elements and a treatment manual. A social media campaign will be conducted from December 2021 to September 2022 to raise brand and issue awareness about smoking cessation for Aboriginal and Torres Strait Islander women in pregnancy. This national campaign will consist of systematic advertising and promotion of iSISTAQUIT and video messages through various social media platforms.

Analysis

We will use the RE-AIM framework (Reach, Effectiveness, Adoption, Implementation and Maintenance) to plan, evaluate and report the intervention impact of iSISTAQUIT. Effectiveness of social media campaign will be assessed via social media metrics, cross-sectional surveys, and interviews.

Discussion

This innovative research, using a multi-component intervention, aims to practically apply and integrate a highly translatable smoking cessation intervention in real-world primary care settings in Aboriginal Medical Services and Mainstream services. The research benefits Aboriginal women, babies and their family and community members through improved support for smoking cessation during pregnancy. The intervention is based on accepted Australian and international smoking cessation guidelines, developed and delivered in a culturally appropriate approach for Aboriginal communities.
Dehumanization and mass violence: A study of mental state language in Nazi propaganda (1927–1945)
Authors: Landry Alexander P. , Orr Ram I. , Mere Kayla
Published: November 2022

Dehumanization is frequently cited as a precursor to mass violence, but quantitative support for this notion is scarce. The present work provides such support by examining the dehumanization of Jews in Nazi propaganda. Our linguistic analysis suggests that Jews were progressively denied the capacity for fundamentally human mental experiences leading up to the Holocaust. Given that the recognition of another’s mental experience promotes moral concern, these results are consistent with the theory that dehumanization facilitates violence bydisengaging moral concern. However, after the onset of the Holocaust, our results suggest that Jews were attributed a greater capacity for agentic mental states. We speculate this may reflect a process of demonization in which Nazi propagandists portrayed the Jews as highly capable of planning and intentionality while nonetheless possessing a subhuman moral character. These suggestive results paint a nuanced portrait of the temporal dynamics of dehumanization during the Holocaust and provide impetus for further empirical scrutiny of dehumanization in ecologically valid contexts.
Glycated hemoglobin level dynamics in COVID-19 survivors: 12 months follow-up study after discharge from hospital
Authors: Shestakova Marina , Kononenko Irina , Kalmykovа Zilya , Markova Tatyana , Kaplun Elena , Lysenko Mar’yana , Mokrysheva Natalya
Published: November 2022

Introduction

One of the stages of reproduction of SARS-CoV-2 is the S-protein glycosylation to facilitate penetration into target cells. It has been suggested that SARS-CoV-2 is able to enter erythrocytes, interact with heme and porphyrin, which could influence HbA1c levels. Assessment of HbA1c levels in individuals with acute COVID-19 and after recovery may show clinical relevance of this hypothesis.

Aim

To assess HbA1c levels in patients with COVID-19 in the acute phase and in early (6–8 weeks) and late (52±2 weeks) periods after recovery.

Materials and methods

We conducted a multicenter prospective study, which included patients hospitalized in Endocrinology Research Centre and the City Clinical Hospital № 52" diagnosed with COVID-19, virus identified/ not identified. Patients were divided into three groups according to baseline HbA1c level and the presence or absence of previous history of diabetes previous history of diabetes mellitus (DM): HbA1c ≤ 6.0%, HbA1c > 6.0% and patients with DM. Patients were examined during the acute COVID-19 phase and in early (6–8 weeks) and late (52±2 weeks) periods after recovery. Oral glucose tolerance test was performed in the group with initial HbA1c > 6.0% to clarify the diagnosis.

Results

We included 194 patients in the study. During the follow-up, 52 patients were examined in 6–8 week period: 7 with HbA1c ≤ 6.0%, 34 with HbA1c > 6.0%, 11—with previously diagnosed DM. Carbohydrate metabolism assessment in the later stages (52±2 weeks) after recovery was performed in 78 patients: 33 patients with HbA1c ≤ 6.0%, 36 patients with HbA1c > 6.0% and 9 patients with previously established diabetes. HbA1c median in patients with HbA1c ≤ 6.0% was 5.7% [5.3;5.8], with HbA1c>6.0% -6.4% [6.2; 6.6], with previously diagnosed DM—7.7% [7.2; 8.9]. Statistically significant decrease in HbA1c over time 6–8 weeks after extracts were obtained in both groups of individuals without a history of DM (Wilcoxon test, p<0.05). After 52±2 weeks we observed HbA1c decrease in all three groups (Fridman test, p<0.05): in patients with HbA1c ≤ 6.0% median HbA1c was 5.5[5.3;5.7], with HbA1c>6.0% - 6.1[6.15;6.54], with previously diagnosed DM—7.8 [5.83; 8.08]. Development of DM after 52±2 weeks was recorded in 7.24% of all examined patients without a history of DM, which is 16.6% of the total number of patients examined in dynamics with HbA1c > 6.0%.

Conclusion

HbA1c elevation during the acute phase of COVID-19 may be false due to the effect of SARS-CoV-2 on hemoglobin kinetics and/or detection on the surface of the SARS-CoV-2 virion highly glycosylated S-proteins by high performance liquid chromatography determinations. Upon detection HbA1c > 6.0% in patients with COVID-19 in the active phase of the disease without concomitant hyperglycemia re-determine the level of HbA1c after recovery is recommended.
Cultivation mode of new accounting talents in the context of financial and taxation digitalization
Authors: Wu Shuangshuang
Published: November 2022

With the development of digital economy, the degree of enterprise digitalization is regarded as the core competitiveness. Therefore, cultivating financial and digital accounting talents has become the mainstream trend. This paper determines the weight of each factor through the entropy right method, and sorts the importance of the evaluation index of the new accounting talent training. On this basis, the factors affecting the training of new accounting talents are analyzed and evaluated. In order to adapt to the development of digital economy society, cultivate compound accounting talents with cross-border knowledge for the society.
Mutation analysis of the GSDME gene in a Chinese family with non-syndromic hearing loss
Authors: Lei Peiliang , Zhu Qingwen , Dong Wenrong , Zhang Siqi , Sun Yanyan , Du Xitong , Geng Meng , Jiang Yuan
Published: November 2022

Background

Hearing loss is considered one of the most common sensory nervous system defects, about 60% of which are caused by genetic factors. Mutations in the GSDME gene are responsible for post-lingual, progressive, autosomal dominant hearing loss. This study aimed to characterize the genetic mutations and clinical features of a Chinese GSDME family.

Methods

After clinical evaluations, high-throughput DNA sequencing was conducted using DNA samples from this family. Sanger sequencing was performed to verify the suspected variants. A detailed genotype and phenotype analysis were carried out. Gene set enrichment analysis (GSEA) was performed to identify the signaling pathway associated with GSDME expression.

Results

A known hotspot heterozygous splice-site variation (c.991-15_991_13delTTC) was identified and shown to segregate with the hearing loss phenotype in the family. This pathogenic splice-site variant results in skipping of exon 8. GSEA analysis identified changes in regulation of the cell cycle checkpoint, peroxisome, and amino acid metabolism signaling pathways.

Conclusions

We identified a reported mutation in the GSDME gene. Our findings support the 3 bp deletion (c.991-15_991-13del) was a hotspot variation, and it emerged as an essential contributor to autosomal dominant progressive hearing loss in East Asians. GSDME gene is closely associated with a range of signaling pathways. These characterized findings may provide new evidence for pathogenesis.
Ensemble learning-based feature engineering to analyze maternal health during pregnancy and health risk prediction
Authors: Raza Ali , Siddiqui Hafeez Ur Rehman , Munir Kashif , Almutairi Mubarak , Rustam Furqan , Ashraf Imran
Published: November 2022

Maternal health is an important aspect of women’s health during pregnancy, childbirth, and the postpartum period. Specifically, during pregnancy, different health factors like age, blood disorders, heart rate, etc. can lead to pregnancy complications. Detecting such health factors can alleviate the risk of pregnancy-related complications. This study aims to develop an artificial neural network-based system for predicting maternal health risks using health data records. A novel deep neural network architecture, DT-BiLTCN is proposed that uses decision trees, a bidirectional long short-term memory network, and a temporal convolutional network. Experiments involve using a dataset of 1218 samples collected from maternal health care, hospitals, and community clinics using the IoT-based risk monitoring system. Class imbalance is resolved using the synthetic minority oversampling technique. DT-BiLTCN provides a feature set to obtain high accuracy results which in this case are provided by the support vector machine with a 98% accuracy. Maternal health exploratory data analysis reveals that the health conditions which are the strongest indications of health risk during pregnancy are diastolic and systolic blood pressure, heart rate, and age of pregnant women. Using the proposed model, timely prediction of health risks associated with pregnant women can be made thus mitigating the risk of health complications which helps to save lives.
Social media networks as platforms for culture and identity interplay among Qatari youth
Authors: Ahmed Ismail Sheikh Yusuf , Miladi Noureddine , Messaoud Moez Ben , Labidi Fatima , Ashour Abeer , Almohannadi Hamda , Fetais Abdallah , Alkhateeb Ghena , Alorfe Anwar
Published: November 2022

The popularity of social networking platforms has increased dramatically in recent years, impacting how people communicate, exchange ideas and exert influence on others. These platforms have provided new opportunities for people to connect and engage with each other, ultimately reshaping their sense of belonging and constructing their identity. The current study focuses on how Qatari youth use social media networks as a tool for identity interaction. By examining the motives for, perceptions about and impacts of social media usage, this study provides insights into how the Qatari youth use these platforms. The research employed a quantitative method, collecting data via an online survey administered through Google Forms. A total of 532 Qatari youth responded to the study. This study’s findings illustrate that most youth use social networks frequently, with half stating that they are always connected. In addition, over 40 per cent report subscribing to one to five groups on social networks. The primary motivation for joining these groups is to engage in discussion about social and political issues as well as to stay up-to-date on the news about their community. According to this study, the most popular social media platform among Qatari youth is Instagram, followed by WhatsApp and Twitter. People use these platforms for different reasons, but many find them to be helpful in staying connected with friends and family, sharing news and experiences and staying up-to-date on current events. Moreover, nearly half of the youth who took part in this study claimed that social media had contributed to creating role models in society. This indicates that social media may play a significant role in shaping young people’s identity and their sense of belonging. A significant number of respondents reported that social media role models influenced their personal choices such as dress, perfumes, language and fashion. This suggests that social media play an unmissable part in shaping individuals’ personal preferences and their cultural identities.
Coronary Artery Stenosis Caused by Primary Malignant Pericardial Mesothelioma in a 76-Year-Old Man
Authors: Machii Yojiro , Sezai Akira , Taoka Makoto , Osaka Shunji , Suzuki Keito , Onuki Yoshiki , Tanaka Masashi
Published: November 2022

This report describes a 76-year-old man with diabetes mellitus who developed coronary artery stenosis from infiltration of a primary malignant pericardial mesothelioma. Three months before referral to the treating hospital, elevated liver function values and cardiac enzymes led to echocardiography, which revealed a motion abnormality in the anterior wall of the heart. The patient was diagnosed with congestive heart failure and admitted to the hospital, where chest computed tomography showed a tumor above the left atrial appendage that compressed the origin of the left anterior descending artery. He was referred to the treating hospital for surgery. Minimally invasive direct coronary artery bypass grafting was performed, but the mass was not resected because of its infiltrating nature and the potential for medical complications. Histologic examination of a biopsy specimen confirmed a primary malignant pericardial mesothelioma. The bypass procedure resolved the coronary artery stenosis caused by the tumor. Although the optimal treatment for primary malignant pericardial mesothelioma is controversial, minimally invasive methods, such as minimally invasive direct coronary artery bypass grafting, may be used successfully.
ANALISIS PENERAPAN ELEKTRONIK LAPOR (E-LAPOR) DALAM PELAYANAN PENGADUAN MASYARAKAT (Studi di Kantor Dinas Komunikasi, Informatika dan Statistik Provinsi Bengkulu)
Authors: Triyanto Deni , Segerlaksono Beni , Darmawi Edi
Published: November 2022

The purpose of this study is to describe the application of the Electronic-LAPOR (E-LAPOR) in Public Complaint Services at the Office of the Communication, Informatics and Statistics Office of Bengkulu Province. The method used in this study is a qualitative descriptive method with data sources namely primary data obtained through observation, interviews and secondary data obtained through data on the E-Report application. The results of this study can be concluded that the application of E-LAPOR in public complaint services at the Bengkulu Province Communication, Informatics and Statistics Office in principle has implemented E-LAPOR services in accordance with Standard Operational Procedures (SOP) as well as indicators of application and service of complaints run well so that the process Community services can be followed up by the Communication, Informatics and Statistics Office of Bengkulu Province in the form of aspirations, suggestions and criticisms or complaints. However, apart from that, there needs to be an increase in human resources in each OPD in Bengkulu Province as well as an increase in socialization to officials as E-LAPOR managers and the general public as service users both directly and through social media because this will affect the results and performance in implementing E-LAPOR.
INOVASI PELAYANAN SUPERONE (SURAT PENGANTAR ONLINE) DI KECAMATAN CANDISARI KOTA SEMARANG
Authors: Tiaranika Usy , Maesaroh Maesaroh
Published: November 2022

There are many challenges and obstacles faced by the government in implementing public services until now. The emergence of public service problems must be resolved immediately in order to create good governance by applying E-Government. Based on the Regulation of the Mayor of Semarang, Candisari District, in this case, also runs the District Integrated Administration Service (PATEN) standard by making an innovation in the form of an online cover letter through an application called SUPERONE in order to achieve a fast, effective and efficient online-based service system. The purpose of this study is to analyze how the SUPERONE application innovation in Candisari District, Semarang City and to find out the inhibiting factors of the SUPERONE application innovation in Candisari District, Semarang City. The research design used in this research is qualitative research with descriptive research type. The results of this study, namely the SUPERONE application can solve public service problems, but in practice there are obstacles, namely there are still many people who do not know about the SUPERONE application, the lack of public knowledge in supporting this change project, the less maximal use of smartphones in the community in administering administrative services, lack of quality and the quantity of technical human resources in providing services, the absence of a mobile application (android) that supports administrative services.
PENGARUH KEBIJAKAN WORK FROM HOME TERHADAP KINERJA PEGAWAI SMK SMAK PADANG
Authors: Astuti Ismaya Indri
Published: November 2022

Menindaklanjuti Instruksi Presiden dan situasi wabah Covid-19, Kementerian Perindustrian Republik Indonesia mengambil berbagai kebijakan terkait Work from Home. Sejalan dengan Surat Edaran dari Menteri Perindustrian, SMK SMAK Padang juga menerapkan hal yang sama. Skema pelaksanaan Work from Home yaitu dengan melaksanakan pekerjaan yang fleksibel di mana para pegawai dapat mengerjakan dan menyelesaikan tugas-tugasnya dari rumah. Peneliti ini bertujuan untuk mengetahui bagaimana pelaksanaan Work from Home di SMK SMAK Padang dan untuk mengetahui apa saja pengaruh kebijakan Work from Home terhadap kinerja pegawai di lingkungan SMK SMAK Padang, sehingga dapat menggambarkan realita dan kondisi sebenarnya di lapangan secara mendalam. SMK SMAK Padang dalam mewujudkan pelaksanaan Work from Home yang efektif dan produktif membutuhkan komunikasi baik dan kerjasama antara pegawai maupun dari atasan langsung, sehingga dapat meminimalkan kendala-kendala yang mungkin terjadi selama Work from Home. Meskipun demikian penerapan kebijakan Work from Home secara tidak langsung meningkatkan semangat pegawai, sehingga pegawai lebih kreatif dan produktif dalam menyelesaikan tugas-tugasnya.
Seed priming with sodium nitroprusside enhances the growth of peanuts (Arachis hypogaea L.) under drought stress
Authors: Tran Thang Thanh , Tran Huong Thanh , Bui Viet Trang
Published: November 2022

Peanuts are a nutrient-dense legume with high lipid, protein, vitamin and mineral content. Peanut development is harmed by drought stress, particularly during the germination and seedling stages. Finding ways to mitigate the impacts of drought stress will have positive effects on peanut production. Seed priming, a short-gun strategy for modulating the impact of abiotic stressors on agricultural plants, has lately piqued the attention of researchers to instill drought tolerance in important crops. In this study, peanut seeds (VD01-2 cultivar) were used as material to investigate the role of priming with sodium nitroprusside at different concentrations (10, 15, 20 and 25 mg L-1) in preventing the damage of peanuts triggered by drought stress. Morphological, physiological and biochemical changes during the development of peanuts in the drought stress condition were analyzed. The results show that moderate drought stress (60% of field capacity) reduced germination and seedling growth. Drought stress reduced relative water content, photosynthesis, and the content of chlorophyll and starch significantly over the control. Seed priming with 20 mg L-1 sodium nitroprusside was effective in increasing these above mentioned growth parameters. Further, the priming of 20 mg L-1 sodium nitroprusside enhanced respiration rate and carotenoid, soluble sugar and proline content compared to the control.
Auf dem Weg zum Dritten Ort
Authors: Kaufer Marion
Published: November 2022

In den Jahren 2020/2021 wurde der Eingangsbereich der Vorarlberger Landesbibliothek in Bregenz umgebaut und modernisiert. Als Ergebnis des Bauvorhabens verändert das neue Eingangsportal nicht nur die grundlegende Betrachtungsweise des Gebäudekomplexes, sondern schafft mit neuen Räumlichkeiten einen Ort zur Begegnung und Interaktion. Der Artikel beschreibt die verschiedenen Bauphasen, unterschiedliche Herausforderungen des Bauprojekts und die Stärkung des Dritten Orts.
Metrology in health: challenges and solutions in infusion therapy and diagnostics
Authors: Metaxiotou Zoe , Bissig Hugo , Batista Elsa , do Céu Ferreira Maria , Timmerman Annemoon
Published: November 2022

The significance of Metrology in infusion therapy and diagnostics, both critical in health care safety and quality, is discussed in this article. Although infusion therapy is the most used form of drug administration, infusion errors are often made with reported dramatic effects in different applications, especially in neonatology. Adverse incidents, morbidity, and mortality have often been traced back to poor or inaccurate dosing. For critical infusion applications to vulnerable patients, well-controlled medication administration might be accomplished by improved dosing accuracy, traceable measurement of volume, flow, and pressure in existing drug delivery devices and in-line sensors operating at very low flow rates. To this end, the contribution of recently upgraded metrological infrastructures in European Metrology Institutes to a safer infusion therapy in health care is described in detail. Diagnostics, on the other hand is a sector characterized by rapid developments further triggered recently by the necessity for the management and prevention of infectious diseases like COVID-19. In this context, the impact of metrology in future large-scale commercialization of next generation diagnostics (e.g., point-of-care) is highlighted. Moreover, the latest contributions of Metrology in the development of traceable testing methods and protocols to ensure the sensitivity and accuracy of these devices are described.
“Taken to German Villages and Liquidated.” The “Selbstschutz” Organization and the Bogdanovka Massacre in 1941
Authors: Hillen Aiko
Published: November 2022

The killing of up to 40,000–50,000 Jews in Bogdanovka in the winter of 1941–1942 represented one of the largest murder operations carried out during the Holocaust outside of Auschwitz, Sobibor and Treblinka extermination camps. The massacre was the result of a cooperation between the German "Sonderkommando Russland" with the support of the "volksdeutscher Selbstschutz" as well as the Romanian gendarmes and their Ukrainian auxiliary forces. This article examines this massacre in three different aspects. The first part reconstructs how Transnistria was administered on a bilateral level between Nazi Germany and fascist Romania, and became a place of mass extermination. The second part of the article deals with the reconstruction of the massacre in a micro-historical perspective by using chiefly eyewitness interviews of local residents. The last part of this work, which is based on an organizational sociological approach, examines the mobilization and willingness to kill of those ethnic Germans who were recruited by the Sonderkommando Russland.
A multivariate analysis of causativedoand causativemakein Middle English
Authors: Moretti Lorenzo
Published: November 2022

Middle English had a rich inventory of verbs that could be used as causatives in periphrastic (or analytic) constructions. Interestingly, we see that two verbs likedoandmake, which share several similarities in their basic meaning, are both used as causative verbs. The present paper explores the relationship and the uses of causativedoand causativemakewith an infinitive complement in the Middle English period. By means of a Multiple Correspondence Analysis (MCA), it will be investigated which semantic domains are more distinctively associated with each verb. The results of the statistical analysis will shed light on the semantic features that characterise these two verbs in Middle English. In addition, the quantitative analysis will help us understand whymakebegan to be used as a causative verb and how productive these verbs were in Middle English.
Assessment of malformations, variations and diameters of vessels forming the circle of Willis – An autopsy study in a non-cerebrovascular cohort
Authors: Orosz László , Gyöngyösi Zoltán , Susán Zsolt , Siró Péter , Hoksbergen Arjan Willem , Csiba László , Fülesdi Béla
Published: November 2022

Background a purpose

The collateral capacity of the circle of Willis (CoW) may play an important role in the development of ischemic strokes. The occurrence of classical polygon shows wide geographical variations and morphological data on diameters of the Willisian collaterals are scarce. We aimed to assess CoW variations and vessel diameters in a Central European cohort.

Subjects and methods

CoWs were removed during routine autopsy. The morphological pattern of the circles was recorded. The prepared circles were then put between two glass plates and tightly compressed. The length of the vessels and half of the circumference were measured under a light microscope enabling measurement with an approximation of 0.1 mm. Vessel diameters were calculated from vessel circumference.

Results

A total of 110 circles were analysed. Incomplete circles (missing one or two segments of CoW) were found in 25 cases (22.7%). Any forms of anatomical variations were detected in 14 cases (12.7%). When applying the <1 mm diameter threshold for analysis, 36 anterior communicating arteries (32.7%), 53 right posterior communicating arteries (48.2%), 73 left posterior communicating arteries (66.4%) and 18 posterior communicating arteries (16.3%) on both the sides were considered hypoplastic.

Conclusions

In patients without stroke in their history, complete CoW may be present in >60% of the cases. Our diameter data may serve as reference values for the Central-European population.
Isolation and purification of 12 flavonoid glycosides from Ginkgo biloba extract using sephadex LH-20 and preparative high-performance liquid chromatography
Authors: Li Ping , Sun Hao , Li Wei , Wu Qi , Ye Shuhong , Zhu Jingbo , Ding Yan
Published: November 2022

An efficient and rapid preparative method for the separation and purification of flavonoid glycosides from the Ginkgo biloba extract (GBE) was developed by sephadex LH-20 and preparative high-performance liquid chromatography (HPLC). 40 g GBE of 24% flavonoids were loaded onto the sephadex LH-20 column and five fractions (1.15, 2.57, 1.32, 4.45, and 3.31 g) at flavonoid content of 72.3, 54.2, 63.5, 51.2, and 59.2% were produced. Ultimately, 12 flavonoid glycosides that are at least purities of 97.7% were obtained from 100 mg of each fraction by preparative HPLC. The fraction A, B, and D each contained two flavonoids, yielded 35, 30, 23, 20, 25, and 25 mg, respectively. The fraction C and E each contained three flavonoids, produced 20, 13, 15, 18, 15, and 20 mg, respectively. The chemical structures of the purified compounds were identified by nuclear magnetic resonance (NMR) and electrospray ionization mass spectrometry (ESI/MS).
Higher Education and the COVID-19 Pandemic. Cross-national Perspectives on the Challenges and Management of Higher Education in Crisis Times
Authors: Fetter Bálint
Published: November 2022

Fetter Bálint a következő művet mutatta be:

Higher Education and the COVID-19 Pandemic. Cross-national Perspectives on the Challenges and Management of Higher Education in Crisis Times. Edited by: Fulufhelo Netswera; Ayenachew A. Woldegiyorgis And Tatiana Karabchuk. Brill, 410 P.
Instrument for the evaluation of the chronic wounded patient: clinical, care and financial indicators
Authors: Garcia Taysa de Fátima , Borges Eline Lima , Alonso Claudiomiro da Silva , Abreu Mery Natali Silva
Published: November 2022

Objectives: to validate an instrument for the assessment of patients with chronic wounds, and to propose clinical, care and financial indicators for Primary and Secondary Health Care. Methods: methodological study involving the development and validation of an instrument consisting of four dimensions with 90 items. The sample was composed of 21 judges, nurses working in Primary or Secondary Care, who evaluated the dimensions of each item regarding comprehensiveness, clarity, relevance and representativeness. Data were analyzed by descriptive statistics and validation by the Content Validity Index. Results: the mean experience of the judges in Primary Care was 7.4 years and in Secondary Care 7.8 years. The index of content validity of each item of the instrument ranged from 0.95 to one, and of each dimension from 0.99 to one, resulting in an overall value of 0.99. Conclusion: this study enabled the development and validation of the instrument. Contributions to practice: the instrument can parameterize data collection and support the generation of clinical, care and financial indicators of the service.
Environmental Technologies and the Specifics of Their use in the Educational Process
Authors:   Voronezh State Pedagogical University, Netsenko Olga Viktorovna , Sulimin Kirill Eduardovich ,   Voronezh State Pedagogical University
Published: November 2022

The article considers different interpretations of the concept “environmental technology” and the essence of environmental technology in order to respond to educational problems and reveals the peculiarities of using such technology in the practice of educational activities with risks and limitations. The aim of the article. To clarify how deeply the concept of “environmental technology” is studied in pedagogy in relation to the educational process and educational activities, what are the possibilities of environmental technology in solving current educational problems, what are the features of using the environmental technology by teachers, to give a classification of environmental technologies. Methodology and research methods. The methodology includes: 1) the environmental approach which assumes studying not only influences of environment on development of the person, but also various aspects of transformation of environment as a solution of educational problems, as well as pays attention to using of components of educational and sociocultural environment in educational process; 2) the system approach considering environment of the educational organization as a component of educational system, and interaction with environment (internal and external) and its positive transformation as means of education, studying environment and its positive transformation. Results of research. The authors interpret environmental technology as a certain order (algorithm) of the teacher’s actions aimed at solving problems of education and positive socialization of the child through diagnostic, designing, modeling, transformation and using of the environment potential (educational, educational, socio-cultural, etc.). In addition to the concept of environmental technologies, the concepts of “technology of the environmental approach to education”, “technology of environmental design”, “technology of improving the environment” are used. All these concepts may be termed as “environmental technology”. Considering the classification of environmental technologies, the authors conclude that most of the researchers consider the function of environmental technologies as the basis for dividing environmental technologies into types and subspecies. Conclusion. Using environmental technology in the educational process, when the pupil is perceived as a part of environment transformed, healed, studied, filled with meanings and values, will put into practice such relevant pedagogical ideas and operating principles as cooperation, independence, group-creative activity, self-development, self-government, responsibility, openness, mutual support.
Animation Educational Technologies in the Scientific and Methodological Support of the Classroom Teacher Training
Authors:   Novosibirsk State Pedagogical University, Shulga Irina Ivanovna
Published: November 2022

The article actualizes the technological aspects of the professional training of classroom teachers for educational work with students in the context of the inclusion of extracurricular activities in the Federal State Educational Standard of basic general education, the introduction of an exemplary education program, which notes the educational potential of children’s leisure practices at school. At the heart of such training is the orientation towards mastering by students a complex of special knowledge, skills and abilities, as well as the acquisition of independent experience of leisure and educational activities in the educational process and professional pedagogical practice. The purpose of the article is to substantiate the need and reveal the possibilities of animation educational technologies as one of the options for scientific and methodological support of educational activities and professional pedagogical practice at the university for students to master a complex of special knowledge, skills and abilities, as well as to acquire independent experience of leisure and educational activities for the effective implementation of the activities of the classroom teacher. Methodology. The study was conducted on the basis of the implementation of a model of scientific and methodological support for the preparation of pedagogical university students for pedagogical animation, which assumed the organization of the educational process in the form of a set of personality-oriented educational technologies (gaming, theater, pedagogical improvisation, individual support and professional tests, etc.) providing the opportunity for students to develop organizational, communicative, reflexive and analytical abilities, necessary and sufficient for effective activity as classroom teachers. In conclusion, it is concluded that animation educational technologies, provided they are adapted to the recommendations of the exemplary education program, can be considered as one of the options for scientific and methodological support for the training of pedagogical university students as classroom teachers.
Analysis of the hydrochemical state in fisheries water bodies
Authors:   Institute of Fisheries of the National Academy of Agrarian Sciences, Kyiv, Dragan L. , Bersan T. ,   Institute of Fisheries of the National Academy of Agrarian Sciences, Kyiv, Mikhailenko N. ,   Institute of Fisheries of the National Academy of Agrarian Sciences, Kyiv
Published: November 2022

Purpose. To assess the quality of the temperature and hydrochemical regime of ponds during the cultivation of common carp and Chinese carp during the growing season. Methodology. Determination of physical properties and gas composition of water (temperature and content of oxygen dissolved in water) was carried out directly at the place of sampling. Measurement of the chemical indicators of water — the content of ammonium nitrogen, nitrites, nitrates, phosphates and total iron - was determined by the photometric method and the concentration of chlorides — by the argentometric titration method. The hydrogen indicator (pH) was determined electrometrically, and the content of sulphates and mineralization - by the gravimetric method. All the above-mentioned methods are the most significant parameters in the comprehensive assessment for the state of aquatic ecosystems. Findings. In laboratory conditions, the main components of the chemical composition in pond for fisheries, which characterize its physical properties (hydrogen pH index, hardness), salt composition (chlorides, sulphates, calcium, magnesium, sodium, and hydrocarbonates), biogenic elements (ammonium nitrogen, nitrites, and nitrates), phosphates, iron. The obtained results of the laboratory analysis of the chemical composition of water samples, as well as their comparison with the maximum permissible concentrations of substances (MPC) in water bodies for fisheries provide grounds for certain conclusions about the ecological state in accordance with purpose to the cultivation of common carp and Chinese carp. Originality. Continuation study of the seasonal fluctuations dynamics of the temperature and chemical regime in the fish ponds of the SE “Research farm “Nyvka” (Kyiv) during the vegetation season of common carp and polyculture (common carp and Chinese carp) in order to outline the potential opportunities for commercial fish cultivation under the influence of abiotic factors. Practical Value. The obtained results are necessary to establish the possibilities for using ponds with the purpose of growing some types of marketable fish, namely: common carp and Chinese carp. Key words: temperature and hydrochemical regime of ponds, components of the chemical composition of water in fisheries water bodies, common carp, Chinese carp.
Use of prebiotic «Actigen» in fish feeding (a review)
Authors:   Institute of Fisheries of the NAAS, Kyiv, Dobryanska O. , Deren O. ,   Institute of Fisheries of the NAAS, Kyiv, Simon М. ,   Institute of Fisheries of the NAAS, Kyiv, Kolesnik R. ,   Institute of Fisheries of the NAAS, Kyiv
Published: November 2022

Purpose. Analyzethe array of special specialized literature and to summarize the information obtained regarding the use of the drug «Actigen» in the sub-branches of animal husbandry, to highlight its main characteristics and mechanism of biological action, to substantiate the prospects of its use in fish farming. Findings. An analysis of modern scientific publications is presented, which reflect the peculiarities of the drug «Actigen», as well as its pharmacokinetics and pharmacodynamics. Its advantages among prebiotic preparations, the effectiveness of its use in animal husbandry and aquaculture, as well as the degree of scientific and research coverage of this issue are outlined. Literary data on the main directions of this drug action to the fish organism are summarized. Thus, the effect of «Actigen» on the intestinal microbiome and non-specific immunity of fish is highlighted. The possibility of replacing it with the use of antibiotics and therapeutic and preventive drugs in fish farming was considered. The prospect of nourishing this drug as an additive to the main feed was analyzed in order to reduce the feed conversion ratio and improve fish-biological indicators. The expediency of using the drug «Actigen» in fish feeding is shown. Practical Value. The review can be useful for scientists, researchers, students, civil servants and private entrepreneurs who are involved in the production processes of feed additives for fish and fishery products. Keywords: «Actigen», prebiotics, fish feed, microbiome, opportunistic microorganisms, antibiotics, mananooligosaccharides.
Risk factors associated with hypertension among inmates in southern Brazil
Authors: Ramos Alexandre Inácio , Palombit Mateus Rodrigo , Sinski Kassiano Carlos , Maciel Ronaldo Luchesi , Abrantes de Oliveira Simoneti Rafaela Azevedo , De Brito Pitilin Erica , Furlan de Léo Marcela Martins , Santos Araújo Jeferson , Conceição Vander Monteiro da
Published: November 2022

Objective: To identify the association between risk factors for systemic arterial hypertension and blood pressure levels in prisoners under a closed regime.
Materials and methods: Cross-sectional study conducted with prisoners under a closed regime between February and September 2019. A total of 240 men from a penitentiary complex in southern Brazil participated in the study. A semi-structured instrument based on the national guidelines for cardiovascular diseases was used for data collection.
Results: Univariate analysis allowed us to identify that physical exercise was negatively associated with the development of systemic arterial hypertension (p = 0.034). However, body mass index and abdominal circumference were positively associated with cardiovascular risk and systemic arterial hypertension (p = 0.000). Through multivariate analysis, we noted the statistical significance of the body mass index when controlled for all other variables in the model (adjusted OR = 2.33).
Conclusions: Risk factors for the development of systemic arterial hypertension are present in the prison environment to a similar degree as in the general population; particularly the absence ofphysical exercise and altered body mass index and abdominal circumference. It is worth mentioning that the body mass index was the variable of greater statistical significance, since, when altered, it increased 2.33 times the chance of inmates to develop systemic arterial hypertension.
Human density and sampling time explain richness of anurans in the brazilian biomes
Authors: Protázio Arielson dos Santos , Conceição Lennise Costa , Protázio Airan dos Santos
Published: November 2022

Anuran richness patterns are strongly influenced by environmental factors. However, investigations on this issue have focused on the influence of abiotic factors without considering the joint effect of many existing variables, including the data sampling methodology and human demography. In this study we investigated the relationship between 21 environmental variables and anuran richness in brazilian biomes. Environmental variables represent a combination of human demographics, topographic, climatic and vegetation characteristics, and data sampling methodologies. We used principal component factorization and regressive and autoregressive models to select the most relevant variables for explaining anuran richness. Richness was correlated with demographic density, vegetation, accumulated rainfall, accumulated rainfall in the third and fourth quarter of the year, and accumulated rainfall in the first and second half of the year. However, the regressive and autoregressive models showed that human demographic density, sampling time, and sampling methodology were the best predictors of anuran richness. Our results highlight the importance of considering the effects of the human footprint and the methodology used for data collection on anuran species richness.