bluuebunny/crossref_metadata_2025 huggingface dataset:
Peran Presiden di Era Pemilihan Langsung dalam Mengikis Politik Diametral
Authors: Ant.T.T Andi Sandi
Published: November 2021

Pemilihan presiden secara langsung akan menyebabkan terbentuknya kondisi politik yang diametral di antara pemenang dan pihak yang kalah. Keadaan politik yang diametral itu disebabkan karena penerapan prinsip winner takes all dan separation of powers dalam origin dan survival antara pemegang kekuasaan pemerintahan serta pemegang kekuasaan legislatif. Prinsip-prinsip ini, yang menjadi cacat bawaan dalam sistem presidensial, merupakan penyebab utama terjadinya dead lock dalam pelaksanaan kekuasaan negara. Apakah ada solusi terhadap cacat bawaan tersebut? Guna menemukan solusi itu, fakta dan data pengalaman Indonesia dianalisis dengan menggunakan metode deskriptif kualitatif. Fakta dan data dalam penulisan ini bersumber dari data sekunder yang dipilah menggunakan purposive sampling. Melalui penggunaan kewenangan dan peran yang dimiliki presiden, kondisi politik diametral dapat diminimalisir ataupun dimitigasi. Khususnya, peran presiden sebagai chief of legislator dan arbiter dipastikan dapat mereduksi maupun memitigasi kondisi politik diametral tersebut.
Bacteriological Analysis of Household Water at the Source and Point of Consumption at Karwar, India
Authors: Kukanur F. Sneha , Sriprada N.S. , Gouda Sheetal , Meghana R. , Naveen G. , Kotian Swapna
Published: November 2021

Access to safe drinking water is the key to promoting good health. At Karwar, the primary source of drinking water is well, but heavy rain, and deficiencies in underground drainage systems result in well water contamination. However, water handling practices followed at the point of consumption act as a better predictor of water contamination. To assess and compare the bacteriological quality of household water at the source and point of consumption. A prospective cross-sectional study was conducted at Karwar. Households owning private wells were selected by Simple Random Sampling. Semi-structured questionnaires were used to interview the households regarding socioeconomic status (SES), chlorination of well, purification method, and water handling practices. Presumptive coliform count and the differential coliform count were determined. Data thus obtained were analyzed using a Microsoft Excel. c2-test was used to see the association between variables. The present study included 30 households. All the samples taken from the well revealed contamination with E. coli. 80% of samples from the point of consumption revealed coliforms, among which 47% were confirmed with E. coli. RO/RO+UV were found to be relatively better performing than the filtration and boiling methods. Contamination of water at the point of consumption had a significant association with both purification and water retrieval methods. The samples taken from the point of consumption reflect better quality of water sampling than source water. The present study revealed post-collection contamination as major reason for compromising water quality despite improved water cleaning and purification techniques.
Clinical Spectrum and Resistance Profile of Staphylococcus Infections in a Peri Urban Tertiary Care Hospital
Authors: Madhuri  , Jangra Sweta , Khandait Manisha
Published: November 2021

Staphylococcus may be evaluated to be a serious microorganism to colonizes and contaminate both the healthy and immuno-competent people in the community along with the hospitalized patients with decreased immunity. This bacterium has been commonly present on the skin and in the nasal cavity of the human body. In the particular sites the organisms may give rise to local diseases of the nose, urethra, vagina and gastrointestinal tract, skin however most of them are minor and not associated with any mortality. S. aureus as well as coagulase-negative staphylococcus which are gram-positive bacteria that lives on the upper respiratory, mouth and skin structure creation, are the possible element for nosocomial and opportunistic disease in humans as well as in animals. Major complications involved with staphylococcus involved SSI, bullous impetigo, skin & soft tissues infection, bacteremia, pulmonary infections etc. The situation is further complicated by methicillin resistance in staphylococcus. MRSA/MRCoNS are considered as the emerging cause of hospital-acquired infections. it is very necessary to quantify the load of infections in order to achieve good hospital infection control policies. Furthermore, the morbidity and mortality rate may also be reduced in the same manner.
Antimicrobial Efficacy of Titanium Dioxide Coating in Operating Theaters at A Tertiary Care Hospital in Arunachal Pradesh
Authors: Umpo Mika , Lollen Tumbi , Jini Moji , Kothapalli Jyothinath
Published: November 2021

SmartCoat is a novel technology with titanium dioxide (TiO2) nanoparticles, isopropyl alcohol, and distilled water as the active ingredients. TiO2, along with water and oxygen, generates highly reactive OH radicals that can neutralize bacteria and other microorganisms and remove volatile organic compounds (VOCs). Smart coat requires air circulation and a light source for its catalytic activity. The efficacy of TiO2 in industrial setups and dental devices has been documented. The present study aimed to evaluate the efficacy of TiO2 in preventing microbial growth in an operating theater (OT) where maximum sterility is desired to prevent sepsis and nosocomial infections. Among the four operating theaters, two were selected. Periodic swab samples taken over a period of nine months from OT 3 (Smart coated) and OT 4 (Control) showed minimal variations in terms of microbial growth in the processed swabs. The findings were statistically analyzed using a paired-sample t-test. The computed value of ‘t’ i.e., 2.084 was lower than the critical value of 3.18 at 3 deg of freedom (df) and hence was not significant. The null hypothesis cannot be rejected (p=0.129>0.05) at the 5% level of significance. SmartCoat with TiO2 was not effective in preventing microbial growth on biomedical devices in the OT. The product may not be suitable for operating theaters unless it is supplemented by other sterilization procedures. However, it can be used in other healthcare settings and in public places.
Isolation of Taxol and Flavin-like fluorochrome from Endophytic Fungi of Mangifera indica
Authors: Jagan Enthai Ganeshan , Sharma Parth , Sureshkumar Senthuran , Pandi Mohan
Published: November 2021

Scouting for novel and plant-derived biomolecules from endophytic microbial sources draws greater focus on the discovery of novel bioactive metabolites. With this rationale, we scouted the endophytic fungi for taxol, an anticancer diterpenoid and fluorescent biomolecules. In the present study, about 31 endophytic fungal isolates recovered from the Mangifera indica leaves were screened for taxol production in M1D medium. About five isolates were shortlisted based on the thin layer chromatographic analysis of the fungal extracts. Among them Colletotrichum sp. MIP-5 has been identified as a producer of fungal taxol based on UV, FTIR, TLC and HPLC analysis. The partially purified fungal taxol showed similar spectral and chromatographic features of commercially available paclitaxel. In addition to this, we also report the production of a fluorescent compound by Penicillium sp. MIP-3. The Flavin-like compound exhibited a bright greenish-yellow fluorescence with an emission maximum in the range of 505 – 545nm. GC-MS analysis showed the occurrence of Latia luciferin, primarily associated with the bioluminescence of freshwater limpet Latia neritoides. This is the first report of this compound from Penicillium sp. In addition, therapeutically active steroid (β-Sitosterol, Stigmasterol, Campesterol), quinones (Benzo[h]quinoline, 2,4-dimethyl-) and phloroglucinol (Aspidinol) derivatives were also identified from Penicillium sp. MIP-3 based on GC-MS analysis. These molecules could potentially be used in biological and pharmaceutical applications in future.
Water Level Monitoring and Dam Valve Control over IOT
Authors: Vispute Shweta Ashok
Published: November 2021

Abstract: This project gives an outline for the development of an information system based on the existing systems with the utilization of some sensors and IOT. The cradle of this project is based on methodology of IOT. Water level in a dam needs to be maintained effectively to avoid complications. The quantity of water released is hardly ever correct resulting in wastage of water and it is impossible for a man to precisely control the gates without knowledge of exact water level and water inflow rate. We have developed a mechatronics based system. We have designed a system in which real time things are interconnected to web. Water level contactless Ultrasonic sensor is placed in tub connected through Arduino UNO to serve the same purpose automatically and forward the status to it. This system detects the level of water and estimate the water inflow rate in a tub and thereby control the Solenoid valve using IOT in a real-time basis. The water level is analysed using this sensor and updated in the web server using IOT module connected to the Arduino UNO. Arduino unit checks that input and upload the status of water level on web. Keywords: IOT (Internet of Things), Mechatronics, Ultrasonic sensor, Arduino UNO, Solenoid valve.
COMPARISON OF MUSCLE LENGTH IN DOMINANT VERSUS NON-DOMINANT LOWER EXTREMITY IN YOUNG ASYMPTOMATIC INDIVIDUALS
Authors: Phansopkar Pratik
Published: November 2021

Muscle length is the length where maximum amount of force a muscle is able to produce. This length is determined by the joint angle that corresponds to the muscle. Understanding the optimal muscle length as well as its comparison between the extremities is very important as a part of examination in physiotherapy. Ranges that are obtained of muscle length helps therapist to recognize individuals with reduced flexibility. Identification and knowledge of muscle length has several role including; evaluation of pre-competition risk for injury, decreased flexibility as an predictor of muscle injury and guides in determining interventional strategy plus training program for an individual. Objectives: To compare muscle length of rectus femoris, hamstring’s, iliopsoas, gastrocnemius in dominant as well as non-dominant side of young asymptomatic individuals in the age group of 18 to 25 years. Method: Through standard goniometer muscle length data was obtained between dominant, non-dominant lower extremity. The methods of assessment used were; active knee extension (AKE) tests the hamstrings length, Thomas and modified Thomas test had been used to evaluate iliopsoas and rectus femoris while prone, figure-four position accompanied by dorsiflexion utilized for gastrocnemius. Result: Values were calculated using goniometric measurements through the group mean values. There is statistically significant variation between the muscle length of hamstring, rectus femoris, iliopsoas and gastrocnemius between the dominant and non-dominant side (p<0.05). Conclusion: Along with data about lower limb muscle length of asymptomatic individuals, we conclude notable difference in dominant to non-dominant extremities muscle length in individuals eighteen to twenty five year.
Identity in the Political Constructions of Modernity: Editorial Introduction
Authors: Fadeeva Lyubov A.
Published: November 2021

L.A. Fadeeva is the author of numerous publications and key co-author of fundamental encyclopedias published by the Russian Academy of Sciences (Identity: The Individual, Society and Politics. An Encyclopedia, 2017) and the Russian Political Science Association (Trends and problems of the development of Russian political science in the global context: Tradition, reception and innovation, 2018), representing the leading scientific school for identity studies in Russia (see: Perm School of Political Science: Sources, Development, Content, 2019), who has served multiple times as guest editor for the thematic issues of the best Russian political science journals on this topic (Political science (RU), 2020, No. 4). In this introductory article, our guest editor L.A. Fadeeva presents the materials of the current issue of our journal, interpreting their cross-cutting themes as the politicization of the non-political through the prism of identity processes at the macro-regional, regional and national levels.
Interpretation of Communism and Post-Communist Transformations in Russia: Modern Theoretical Discussions
Authors: Gutorov Vladimir A. , Shirinyants Alexander A.
Published: November 2021

The analysis of discussions on various aspects of the evolution of the modern state, the specifics of post-communist transformations and the role that Marxism and the tradition of radical socialist thought can play in the near future in their search for a way out of the crisis generated by the agony of the neoliberal global world order. As a starting point for the analysis, theoretical articles published in the second edition of the collection Communism, Anticommunism, Russophobia in post-Soviet Russia. 2nd ed., Add. / Auth.: P.P. Apryshko et al. - Moscow: World of Philosophy, Algorithm, 2021 (607 p.) were selected. A comparative analysis of the polemical works of domestic scientists, political theorists and philosophers with those discussions that for many decades have been conducted by their colleagues abroad clearly indicates that today none of the existing ideologies, as well as the paradigms of economic and socio-political theory, can pretend to be the only recourse. The experience of recent decades clearly excludes the very possibility of transforming the economy and society on the basis of a certain universal synthetic model. In post-communist Russia, the heat of political passions, which stimulates the extreme polarization of political programs for overcoming the crisis, also hinders the achievement of agreement and the search for a solution acceptable to all.
Ideological Preferences of Kaliningrad Residents in the Socio-Political System
Authors: Krishtal Mikhail I.
Published: November 2021

The article analyzes the ideological preferences of the residents of the Kaliningrad region through the prism of their socio-economic situation and political behavior. The study is based on the data of a formalized interview (N = 977) according to the age and sex sample, representing the population of four geodemographic districts of the Kaliningrad region. Based on the Nolan Chart, the study determines ideological types according to the respondents attitude to political and economic freedom. The statistical analysis of the data revealed a high degree of pluralism among the residents of the region on the issues under consideration. At the same time, it showcased the prevailing ideas of state regulation of the economy and values of personal freedom. Analyzing the socio-economic situation of the respondents and their inherent ideological attitudes, the author found that the values of economic freedom are more often shared by young people, middle-aged people, residents living in Kaliningrad, with higher income. Ideas of state regulation of the economy prevail among people of retirement and pre-retirement age, residents of the semi-periphery of the Kaliningrad region, with lower income. The study also revealed the relationship between the ideological attitudes of people in the region and their political behavior. In particular, it found that people who share the values of political and economic freedom are ready to take the most active part in protests. At the same time, the study did not identify any significant links between the ideological type of the respondents and their electoral behavior.
Political Implications of Orthodox Identity: An Example of the World Russian People’s Council
Authors: Shikher Natalya D.
Published: November 2021

The article examines the conceptual ideas of the World Russian Peoples Council, acting under the auspices of the Russian Orthodox Church, regarding the implementation of the right to freedom of conscience and the status of religious associations in Russia. Furthermore, the speeches of heads of the states at the Councils were studied for their attitude to the ideological content of the activities of this organization. On the basis of the data obtained, the author attempts to find a correlation between the proposals voiced at the Councils on changing certain aspects in the religious sphere and the reforms of the Russian legislation on freedom of conscience. As a result of this study, a striking coincidence was revealed between the two factors mentioned: the provisions discussed at the Councils, as a rule, after some time were reflected in Russian normative legal acts. Not having sufficient grounds for declaring an unambiguous causal relationship between conciliar ideas and legislative reform, one can, in any case, assume a significant impact of the activities of the World Russian Peoples Council on the state policy in implementation of the right to freedom of conscience in modern Russia.
Civic Identity: Diversity of Meanings and Achievement of Solidarity
Authors: Mchedlova Maria M. , Sargsyan Hovhannes L.
Published: November 2021

The concept of identity reflects the ongoing shifts in political theories when external parameters that did not previously fall into the optics of political research become a part of political reflection and political analysis. Emphasizing sociocultural issues captures not only the departure from the linear normativity of political theory and pragmatics but also the search for modern explanatory models that cannot be reduced merely to institutional determinism. The controversy and ambiguity of the civic identity concept are imposed on the need for interpreting the formation of civic communities in the newly emerged independent countries after the collapse of the Soviet Union (on the example of Russia and Armenia), including the possibilities of protest and project identity. Methodologically the article is based on the perception that the construction of civic identity cannot be reduced to the normative understanding only. The authors bring out the causal complexes that predetermine the construction of civic identity, while also highlighting the differences in how civic communities and their value focuses are perceived and constructed in Russia and Armenia. The authors also define the general features of civic identity, which can be described as a common basis of solidarity, the removal of particularity and a shared vision of the future.
The Role of Civic Identity in the Evolution of Relations Between Serbian and Croatian Civil Societies
Authors: Djokic Aleksandar , Pichelin Guillaume
Published: November 2021

For decades, Croats and Serbs lived together in a common political construction: Yugoslavia. It is difficult to date the appearance of animosity between Croats and Serbs. Nevertheless, two events proved particularly traumatic for their relations. The Second World War, when the Ustasha led a genocide against the Serbs, and the 1991-1995 war, when the two sides fought a merciless civil war. This article examines the evolution of relations between Serbian and Croatian civil societies from the beginning of the Yugoslavian project to 2021 and how the rise of civic identity in the future might help the process of reconciliation. The main hypothesis of the article is that the failure to construct a viable Yugoslavian civic identity in the past is the cause of ethnic tensions during the 90s. The article entails both qualitative and quantitative methods through which the authors offer explanations about the failure to construct a common Yugoslavian civic identity, how this failure impacted the relations between Serbian and Croatian civil societies, and, finally, what are the prospects of reconciliation and constructing civic identities in the newly formed countries of Serbia and Croatia. Today, relations between the two civil societies remain tense. Serbs in Croatia and Croats in Serbia are subject to unsystematic discrimination, which hinders exchanges between the two countries. This study shows that Serbian and Croatian citizens under 35 years of age, mainly agree that tensions exist. Nevertheless, two-thirds of those questioned in Serbia and three-quarters of those questioned in Croatia believe that reconciliation is possible. This reconciliation becomes even more realistic since an overwhelming majority in both groups want reconciliation.
Not the Far-Right Only: Which Parties Occupy the Niche of Cultural Protectionism in the EU Countries?
Authors: Petrov Ivan I.
Published: November 2021

In the 2010s many moderate parties in Europe began to use the agenda of the far-rights, competing with them on the same field. This article is devoted to the problem of inter-party competition in European countries amidst the rise of far-right parties. We also intended to check if the far-right profile is the same for all EU countries. To achieve the goal of the study, we used two databases on party positioning - MARPOR (Comparative Manifesto Project) and CHES (Chapel Hill Expert Survey). The study revealed that the consolidated family of the far-rights exists only in the countries of North-Western Europe, while in the countries of East-Central Europe the agenda of the far-rights is less consolidated and regionally heterogeneous. The mainstream competitors of the far-rights included mostly conservatives in North-Western Europe, and various parties, including the Social Democrats, in East-Central Europe. The study confirmed the hypothesis about the serious influence of the far-rights on mainstream politics. At the same time, it questioned the traditional approach which attributes the far-right profile only to far-right parties and ignores both regional differences and the factor of spatial competition.
Rancang Bangun Pengendalian Robot Mobil dengan Wireless Joystick PS2 Menggunakan Modul nRF24L01
Authors: Hakim Arif Rahman , Nehru Nehru , Fuady Samratul
Published: November 2021

Robot adalah sebuah alat mekanik yang dapat melakukan tugas fisik baik menggunakan pengawasan dan kontrol manusia, atau program yang sudah tertanam dalam sebuah processor. Dalam suatu pengendalian sistem robot manual, sebagai bentuk komunikasi atau interaksi manusia dengan robot, maka perlu alat yang digunakan untuk komunikasi antara manusia dengan robot, salah satunya adalah telekomunikasi nirkabel. Modul nRF24L01 adalah transceiver chip tunggal yang khusus di desain untuk menyediakan pengaplikasian komunkasi wireless dengan daya yang sangat rendah. Penelitian ini menggunakan dua buah modul nRF24L01 dan dua buah mikrokontroler sebagai media komunikasi. Satu modul nRF24L01 berfungsi sebagai transmitter dan satu modul nRF24L01 sebagai receiver. Robot yang dibuat dapat dikendalikan melaui analog joystick PS2 yang terdapat pada bagian transmitter. Berdasarkan penelitian yang sudah dilakukan dapat diambil kesimpulan bahwa robot yang dibuat dapat dikendalikan menggunakan kontroler dengan jarak maksimal 300 meter.
Patient-Specific Tumor Microenvironment Models
Authors: Lee Jung Woo , Kim Jia , Shin Youngjae , Chi Byung Hoon , Kim Jung Hoon , Choi Se Young
Published: November 2021

The heterogeneity of cancer makes it difficult to predict the prognosis of treatment. There is still a lack of preclinical model systems that reflect the clinical characteristics of patients who have heterogenetic tumors. Advances in 3-dimentional (3D) cell culture are leading to discoveries that occur in the development and progression of cancer that has not been known. There are many models including patient-derived xenograft, patient-derived organoid and spheroid, patient-derived explant, scaffold-based model, and system-based model. Each 3D model has its strengths and limitations. One model cannot answer every question, so it seems most reasonable to approach multiple models when studying cancer heterogeneity. Hopefully, 3D tumor modeling will make tremendous progress on this path by fusion of innovative biomaterials and advanced modeling techniques that can partially mimic the heterogeneous environment of real tumors.
A Study on Metabolic Health Status as a Risk Factor for Female Bladder Cancer Incidence: Analysis From the National Health Checkups Database of Korea
Authors: Han Da Eun , Ahn Sun Tae , Kim Jong Wook , Oh Mi Mi , Moon Du Geon , Han Kyungdo , Park Hong Seok
Published: November 2021

Purpose: This study investigated metabolic health status as a risk factor for female bladder cancer using the National Health Checkups databases of Korea.Materials and Methods: We defined obesity if body mass index was ≥25 kg/m2 and normal weight as <25 kg/m2. Metabolic unhealthiness was defined when 3 or more criteria of metabolic syndrome were met. A total of 11,461,618 women who took National health Checkups between 2009 and 2012 were categorized as metabolic healthy normal weight (MHNW), metabolic unhealthy normal weight (MuHNW), metabolic health obese (MHO), and metabolic unhealthy obese (MuHO). Multivariable-adjusted Cox regression was done to analyze the hazard ratio of bladder cancer.Results: The mean age was 48±11.55 years and body mass index was 23.19±2.13 kg/m2. During 5.4±1.1 years of follow-up, 3,893 patients were newly diagnosed with bladder cancer. Compared to MHNW group, the hazard ratio of MuHNW group and MuHO group were 1.237 and 1.288, respectively, while 0.997 in the MHO group. As the number of metabolic unhealthy criteria increased, the cumulative incidence of bladder cancer increased.Conclusions: As a result of a large-scale study conducted on the female population in Korea, the risk of bladder cancer increased with metabolic unhealthiness. Even with normal weight, if metabolically unhealthy, the risk of bladder cancer increased. The greater the degree of metabolic unhealthiness, the higher the risk of bladder cancer. Education on metabolic healthiness concerning female bladder cancer is necessary.
Risk Factors Leading to Radical Cystectomy in Patients Who Had Undergone Nephroureterectomy
Authors: Lee Janghui , Lim Bumjin , You Dalsan , Jeong In Gab , Song Cheryn , Hong Jun Hyuk , Kim Choung-Soo , Ahn Hanjong , Hong Bumsik
Published: November 2021

Purpose: To identify the risk factors leading to radical cystectomy in patients who had undergone nephroureterectomy (NUx).Materials and Methods: We retrospectively reviewed the medical records of patients with upper tract urothelial carcinoma who underwent NUx during 2011–2019 and excluded patients with metastatic cancer. In total 646 patients were included in this study; of these, 532 had no previous bladder cancer history. Follow-up was performed every 3 months for 2 years after NUx was administered, and recurrence was confirmed using cystoscopy, urine cytology, computed tomography, and chest radiography. Bladder recurrence was confirmed through biopsy, urine cytology, or radiologic examination. Univariate and multivariate Cox regression analyzes were performed for statistical analysis of risk factors leading to radical cystectomy in patients undergoing NUx.Results: Lymphovascular invasion (LVI) (hazard ratio [HR], 4.728; 95% confidence interval [CI], 1.463–15.570; p=0.011), previous transurethral resection of bladder tumor history (HR, 3.825; 95% CI, 1.164–12.571; p=0.027), and intravesical recurrence (IVR) within 6 months (HR, 3.733; 95% CI, 1.091–12.778; p=0.036) in patients undergoing NUx are predictors of radical cystectomy implementation. In a multivariate analysis of patients without bladder cancer history, bladder recurrence was identified as a predictor of radical cystectomy implementation, if it occurred within 6 months of NUx (HR, 8.608; 95% CI, 1.545–47.976; p=0.014).Conclusions: LVI and IVR within 6 months and previous bladder cancer history are factors that can predict the need for radical cystectomy after NUx. Even in patients without bladder cancer history, early bladder recurrence within 6 months is a major predictor of radical cystectomy.
Contratos empresariais e compliance
Authors: Bonamigo Heloisa Führ , Rodrigues Mariana Santos
Published: November 2021

A relevância dos contratos para o desempenho das atividades empresariais e as mudanças no papel da empresa, em um contexto marcado pela superação do viés individualista inerente ao mercado e afastamento das práticas pautadas na busca irrestrita pelo lucro, demandam a análise da função dos contratos empresariais no estabelecimento de relações que estejam em consonância com interesses socialmente legitimados, considerando os impactos da atividade empresarial a terceiros. Objetivo: Partindo-se desta mudança no papel da empresa, objetiva-se questionar de que forma os princípios e características contratuais relacionam-se à proteção de interesses socialmente legitimados, a fim de adequar as relações estabelecidas pela empresa a normas e padrões éticos. Método: A metodologia do artigo consiste em revisão bibliográfica, notadamente acerca das principais caraterísticas dos contratos empresariais, analisando a confiança, função social, boa-fé e influência das externalidades nas relações empresariais, o conceito de compliance e sua aplicabilidade no meio empresarial. Resultado: Aliados ao protagonismo de programas e políticas de compliance em diversas áreas, com a finalidade de prevenir infrações previstas nos respectivos diplomas legais, propõe-se a inserção de cláusulas éticas aos contratos empresariais, como ferramenta de mitigação dos riscos e efetivação de políticas que consideram os impactos da atividade empresarial, passando a figurar como mecanismo de efetivação de políticas de compliance que objetivam proteger a reputação da empresa e mitigar riscos.
Effects of non-steroidal anti-inflammatory drugs and other eicosanoid pathway modifiers on antiviral and allergic responses. EAACI task force on eicosanoids consensus report in times of COVID-19
Authors: Sokolowska Milena , Rovati G Enrico , Diamant Zuzana , Untersmayr Eva , Schwarze Jürgen , Z. Lukasik , Sava Florentina , Angelina Alba , Palomares Oscar , Akdis Cezmi , O'Mahony Liam , Jesenak Milos , Pfaar Oliver , Torres María José , Sanak Marek , Dahlén Sven-Erik , Woszczek Grzegorz
Published: November 2021

Non-steroidal anti-inflammatory drugs (NSAIDs) and other eicosanoid
pathway modifiers are among the most ubiquitously used medications in
the general population. Their broad anti-inflammatory, antipyretic and
analgesic effects are applied against symptoms of respiratory
infections, including SARS-CoV-2, as well as in other acute and chronic
inflammatory diseases that often coexist with allergy and asthma.
However, the current pandemic of COVID-19 also revealed the gaps in our
understanding of their mechanism of action, selectivity and interactions
not only during viral infections and inflammation, but also in asthma
exacerbations, uncontrolled allergic inflammation, and
NSAIDs-exacerbated respiratory disease (NERD). In this context, the
consensus report summarises currently available knowledge, novel
discoveries and controversies regarding the use of NSAIDs in COVID-19,
and the role of NSAIDs in asthma and viral asthma exacerbations. We also
describe here novel mechanisms of action of leukotriene receptor
antagonists (LTRAs), outline how to predict responses to LTRA therapy
and discuss a potential role of LTRA therapy in COVID-19 treatment.
Moreover, we discuss interactions of novel T2 biologicals and other
eicosanoid pathway modifiers on the horizon, such as prostaglandin D2
antagonists and cannabinoids, with eicosanoid pathways, in context of
viral infections and exacerbations of asthma and allergic diseases.
Finally, we identify and summarise the major knowledge gaps and unmet
needs in current eicosanoid research.
Case report of Osteopoikilosis in patient with psoriatic arthritis.
Authors: Cherif Ines , Maatallah kaouther , Ferjani Hanene , TRIKI Wafa , Nessib Dorra Ben , KAFFEL Dhia , Hamdi Wafa
Published: November 2021

Osteopoikilosis(OPK) is one of the rare genetic musculoskeletal, non
inflammatory disorders that we should increase awareness towards. We
report a case of a patient diagnosed with psoriatic arthritis with
incidental imaging findings of lesions suggestive of osteopoikilosis.
Healthcare Utilization and the Quality of Life of Children and Adolescents with Sickle Cell Disease
Authors: Moody Kendall
Published: November 2021

Introduction: Youth diagnosed with sickle cell disease (SCD) often
utilize the healthcare setting to manage disease-related symptoms, yet
the connection between healthcare use and their overall wellbeing has
been understudied. This study investigates whether healthcare
utilization predicts the health-related quality of life (HRQOL) in youth
with SCD. It is hypothesized that increased healthcare utilization will
predict lower HRQOL in pediatric SCD. Methods: A total of 150 patients,
ages 8-17 years old, were enrolled in this cross-sectional quantitative
study. Patients completed the Pediatric Quality of Life (PedsQL) 3.0 SCD
module, while the researcher conducted a retrospective chart review to
gather patient characteristics such as emergency room (ER) and
hospitalization occurrences over the past 12 months. Results: A higher
frequency of ER visits (p < .05) and hospitalizations (p
< .01) predicted lower HRQOL scores. Age (p < .05)
also emerged as a significant predictor for both regression models.
Discussion: As youth with SCD require ER treatment and/or hospital
admission, they are at increased risk for lower HRQOL, specifically as
they get older.
Generalized Riemannian spaces with respect to 4-velocity vectors and functions of state parameters
Authors: Vesic Nenad , Dimitrijevic Dragoljub , Simjanovic Dusan
Published: November 2021

We pointed to 4-dimensional generalized Riemannian spaces important for
applications in some parts of physics here. Complete metric tensors and its
possibilities to be applied in cosmology are analyzed in this paper. We used
the results of N. O. Vesic, presented in [14]. At the end of the paper, we
studied the diagonal symmetric metric tensor in the cosmological context.
Dp,q-classical orthogonal polynomials: An algebraic approach
Authors: Sghaier Mabrouk , Zaatra Mohamed , Mechri Mehdi
Published: November 2021

In this paper, we introduce a new technical method for the study of the
Dp,q-classical orthogonal polynomials where Dp,q is the (p,q)-difference
operator, using basically an algebraic approach. Some new characterizations
are given. The approach has been illustrated with three examples.
On the solvability of some nonlinear functional integral equations on Lp(R+)
Authors: Bousselsal Mahmoud
Published: November 2021

In this paper, we prove theorems on the existence of solutions in Lp(R+), 1 ? p < ?, for some functional integral equations. The basic tool used in the
proof is the fixed point theorem due to Darbo with respect to so called
measure of noncompactness. The obtained results generalize and extend
several ones obtained earlier in many papers and monographs. An example
which shows the applicability of our results is also included.
Synthesis of BaTiO3 from a mechanically activated BaCO3-TiO2 system
Authors: Pavlovic V.P. , Stojanovic B.D. , Pavlovic V.B. , Marinkovic-Stanojevic Z. , Zivkovic Lj. , Ristic M.M.
Published: November 2021

In this article the solid state reaction of BaTiO3 formation from a mechanically activated BaCO3-TiO2 system has been investigated. An equimolar mixture of BaCO3 and TiO2 powders was activated in a planetary ball mill in a continual regime for 0, 30 and 90 min, pressed and thermally treated up to 1200oC. The effect of the milling and firing regime on the phase formation was investigated by the X-ray diffraction (XRD) method and differential thermal analysis (DTA). Deconvolution of the experimental DTA curve corresponding to the BaTiO3 synthesis process has been performed. The influence of the activation time on the change of characteristic temperature for each elementary step in the complete solid-state reaction of BaTiO3 formation, was analyzed. These results were correlated with the ones obtained by SEM characterization and by XRD analysis.
Influence of mechanical activation on elelctrical properties of cordierite ceramics
Authors: Djordjevic N.G. , Jovanic P.B.
Published: November 2021

The goal of the presented research was to find a possible correlation of the process parameters and functional properties of cordierite based ceramic materials. A three component oxide mixture was prepared containing MgO+Al2O3+SiO2 in the 2:2:5 ratio with the addition of 10% Bi2O3. Mixtures were mechanochemically activated 5 and 240 minutes in a mill with ceramic balls, and sintered at temperatures from 1173-1573K. Structural transformations were determined by the XRD method. Quantitative measures of the functional sample properties, capacity Cc and electrical resistance R? as well as tangens of dielectric loss angle tg ? were used. The results obtained proved that there is a correlation between mechanochemical activation and properties of cordierite ceramics.
Monitoring of the morphologic reconstruction of deposited ablation products in laser irradiation of silicon
Authors: Vlasova M. , Aguilar Márquez , Reséndiz-González M.C. , Kakazey M. , Stetsenko V. , Tomila T. , Ragulya A.
Published: November 2021

Using electron microscopy, atomic force microscopy, X-ray microanalysis, and IR spectroscopy, it was established that, in the regime of continuous laser irradiation of silicon at P = 170 W in different gaseous atmospheres with an oxygen impurity, SiOx composite films with a complex morphology form. The main components of ablation products are clusters that form during flight of ablation products and as a result of separation of SiOx-clusters from the zone of the irradiation channel. The roughness and density of the films depend on the heating temperature of the target surface and the type of deposited clusters.
Perceived work situation and work ability among persons who are working one year after stroke
Authors: Lindgren Ingrid , Pessah-Rasmussen Hélène , Gard Gunvor , Brogårdh Christina
Published: November 2021

Objective: To explore how persons who have returned to work perceive their work situation and work ability one year after stroke. Design: Cross-sectional design.Subjects: A total of 88 persons of working age (mean age 52 (standard deviation; SD 8) years, 36% women), with mild to moderate disabilities following stroke, who had returned to work within one year after stroke participated in the study. Methods: A survey including a questionnaire regarding psychological and social factors at work (QPS Nordic) and 4 questions from the Work Ability Index (WAI) was posted to the participants. Results: According to the QPS Nordic survey, 69–94% of respondents perceived their work duties as well defined, and were content with their work performance. Most participants had good social support at work and at home. Between 51% and 64% of respondents reported that they seldom felt stressed at work, seldom had to work overtime, or that work demands seldom interfered with family life. According to the WAI ≥75% of respondents perceived their work ability as sufficient, and they were rather sure that they would still be working 2 years ahead. Conclusion: Persons who have returned to work within one year after stroke appear to be content with their work situation and work ability. Appreciation at work, well-defined and meaningful work duties and support seem to be important for a sustainable work situation
An Analysis of Politeness Principle in Badung Regent Candidates Debate in 2015
Authors: Aryasih Made
Published: November 2021

Abstract This study aimed at: 1) finding maxims of politeness principle expressed in Badung Regent Candidates Debate in 2015; 2) finding the most dominant maxim of politeness principle used in Badung Regent Candidates Debate in 2015. This study was designed mainly as a descriptive qualitative study which then supported by some descriptive quantification. The objects of the study were the utterances containing maxims of politeness principle expressed by the regent and vice regent candidates of Badung in Badung Regent Candidates Debate in 2015. The data were analyzed based on the theory of politeness principle proposed by Leech and the theory of categorization of speech act by Searle. The results of the study display that there are six maxims of politeness principle expressed in Badung Regent Candidates Debate in 2015, namely the tact maxim, the generosity maxim, the approbation maxim, the modest maxim, the agreement maxim and the sympathy maxim. Furthermore, it is found out that the generosity maxim is the most dominant maxim used by the regent and vice regent candidates in Badung Regent Candidates Debate in 2015. The generosity maxim expressed in the debate applied the commissive type of speech act. Through the utterances of this maxim, they intend to convince the audience that they attempt to minimize benefit to self and maximize cost to self. The maxims expressed by the regent and vice regent candidates in the debate have a goal to communicate effectively
THE USE OF YOUTUBE VIDEO IN TEACHING ENGLISH FOR FOREIGN LANGUAGE AT VOCATIONAL HIGH SCHOOL
Authors: Cahyana Agus Agung Canis
Published: November 2021

The study aimed to investigate the use of YouTube video in learning English as a foreign language in terms of the implementation, students' opinion in English skill improvement after the implementation of YouTube video, the problem faced by teachers and students, and students' perception toward the use of YouTube video in learning English. The respondents were 5 tenth grade English teachers and 35 tenth grade students. This study used embedded mixed-method as the research design. The data were gathered by distributing questionnaires, and were analyzed by using SPSS. The result of the study revealed that: a) the teachers could implement the technique since the teachers used YouTube video technique to target several skills in English. The students had positive opinion about the improvement obtained in learning English. The students also mentioned that the implementation of this technique was able to decrease the monotonous teaching and increase the motivation in learning English. However, some problems occurred while the preparation of the assessment process in implementing YouTube video technique such as the internet connection and the students' readiness. The teachers needed to develop the technique to increase the students better understanding of the topic. The result of this study was found out the implementation of YouTube videos in teaching and learning English was showed a positive impact on students' English acquisition and helpful for teachers in delivering the topic to students and the result was in line with the finding of the previous study. However, there were some additional findings in this present study such as the problem the way teachers implemented this technique, the students' opinion in English skill improvement, and the students' perception toward the implementation of the YouTube video technique.
THE USE OF ENGLISH CLASSROOM GREETING AND CHARACTER BUILDING IN TK PELITA SARI DESA MAMBANG TABANAN
Authors: Purandina I Putu Yoga
Published: November 2021

This study aims to determine activities of using English classroom greeting expressions in TK Pelita Sari, Desa Mambang, Tabanan, to find out perceptions of teachers and parents regarding development of English language skills at an early stage for the children who are influenced by habituation of this English classroom greeting activity, and to determine the positive value contained in English classroom greeting expressions on formation of children's characters. A qualitative descriptive method was employed using observation sheets and interview guides to children, teachers and parents. The results show that: first, the activity of using the English Classroom Greeting was a routine activity carried out every day by the children; second, teachers and parents perceived that the use of the expressions provided language experience for the children which resulted in positive development in speaking and listening in English. Third, there were two character values that seemed to develop along with the language experience in using English Classroom Expression, namely, friendly / communicative and social respect.
MODEL KEBIJAKAN PENGEMBANGAN KERJASAMA KEWASPADAAN DINI GEJOLAK SOSIAL ANTARA PEMERINTAH KABUPATEN MESUJI PROVINSI LAMPUNG DAN KABUPATEN OGAN KOMERING ILIR PROVINSI SUMATERA SELATAN (Studi Kerjasama antara Pemerintah Kabupaten Mesuji Provinsi Lampung dan Kabupaten Ogan Komering Ilir Provinsi Sumatera Selatan)
Authors:   Universitas Lampung, Marta Andri , Umayasari Ulfa ,   Universitas Lampung
Published: November 2021

Pilihan kebijakan dalam rangka meningkatkan kapasitas kelembagaan yang rendah dan kualitas sumberdaya aparatur yang sangat minim melalui kebijakan kerjasama antar daerah dalam hal ini jalinan kerjasama antara Kabupaten Mesuji dan Kabupaten Ogan Komering Ilir dalam rangka pemberian penyelesaian konflik sosial serta bagaimana mengembangkan model kebijakan kerjasama kewaspadaan dini gejolak sosial antara Kabupaten Mesuji dan Kabupaten Ogan Komering Ilir. Penelitian ini merupakan penelitian dengan pendekatan kualitatif deskriptif. hasil temuan penelitian yang telah dilakukan dapat disimpulkan bahwa kerjasama antar Pemerintah Kabupaten Mesuji dengan Pemerintah Kabupaten OKI yang berada di wilayah perbatasan merupakan salah satu upaya untuk memecahkan masalah bersama yaitu penyelesaian masalah konflik sosial yang terjadi di daerah tersebut. Implementasi kerjasama antara Pemkab Mesuji dengan Pemkab OKI tidak efektif karena tidak didukung oleh kelembagaan yang kuat, opreasionalisasi program, dukungan anggaran dan penyelesaian masalah yang masih cenderung reaktif, serta model penyelenggaraan pemerintahan yang masih didasarkan pada kuatnya ego-daerah. Oleh karena itu, harus dikembangkan model kerjasama antara pemerintah daerah yang efektif antara lain dengan memperkuat dukukungan institustional, penyediaan program yang oprasional, sifat penyelesaian masalah pada jangka panjang dan dukungan anggaran yang layak.
Current Review of Delta Variant of SARS-CoV-2
Authors: Chowdhury Selia , Bappy Mehedi Hasan , Chowdhury Samia , Chowdhury Md. Shahraj , Chowdhury Nurjahan Shipa
Published: November 2021

Mutations are causing SARS-CoV-2 to alter its genetic structure to improve its potential to elude the immune system, making vaccine buildout against the virus more difficult. Multiple SARS-CoV-2 variants have been found up to this point; based on their impact on public health some are considered variants of concern (VOCs) and some are considered variants of interests. VOCs are linked to superior transmissibility, a decline in neutralization by natural or vaccine induced antibodies, evading capability of detection, and a reduction in the efficacy of vaccines or therapeutics. In this article, a SARS-CoV-2 subtype, known as Delta, has been revised to provide the current state of the art and an appropriate foundation for future research works. The evolution, pathogenesis, current trends of transmission, associated symptoms, suggested prevention and treatments, and vaccine efficacy of Delta variant are reviewed and discussed.
Pengembangan E-Modul Asam Basa Berbasis Literasi Sains
Authors: Ulfa Nadya , Sutiani Ani
Published: November 2021

Teaching material is one of the aspects to improve scientific literacy skills had by students, but based on the analysis of school textbooks, especially on acid-base materials, 2 chemistry textbook do not yet have the maximum application of scientific literacy. The aim of this research is to develop acid base e-module based on scientific literacy. The method implemented is Research and Development (R and D) method by Borg and Gall which is limited to 7 out of 10 stages. The instrument used in this study was questionnaire of validity and practicality. Validation was carried out by 5 validators while the practicality test was distributed to 2 chemistry teachers and 20 students of Class XI Science of SMA Negeri 10 Medan. Based on the validation results obtained from the validators, the average result is 4,70 which a very feasible criteria. The average value of teachers and students practicality responses was 4,60 and 4,42 with a very feasible criteria so it was concluded the acid-base e-module based on scientific literacy is valid, practical and also feasible to be used in learning activities for high school students. The follow-up of this research is to conduct a trial of the effectiveness of using e-modules in improving students’ scientific literacy skills.