bluuebunny/crossref_metadata_2025 huggingface dataset:
The effect of the human cumulus cells-conditioned medium on in vitro maturation of mouse oocyte: An experimental study
Authors: Adib Maryam , Morteza Seifati Seyed , Dehghani Ashkezari Mahmood , Khoradmehr Arezoo , Rezaee-Ranjbar-Sardari Roshan , Sadat Tahajjodi Somayyeh , Aflatoonian Behrouz
Published: December 2020

Background: To increase the results of infertility treatment, many efforts have been made to improve the treatment methods. As assisted reproductive technology is mainly using cell culture methods, one of the approaches to improve this technology is conditioned medium from different sources. It is desirable to apply in vitro maturation (IVM) and use oocytes from normal cycles instead of stimulating ovulation.
Objective: To investigate the effect of human cumulus cell condition medium (hCCCM) on the IVM of immature mouse oocytes and morphology.
Materials and Methods: In this experimental study, 240 germinal vesile oocytes were collected from four-six wk-old mice after 48 hr of 5IU pregnant mare serum gonadotropin (PMSG) injection and cultured in hCCCM (test group, n = 120) and DMEM + 20% FBS (control group, n = 120). The IVM rates and changes in perivitelline space (PVS) and shape were investigated at 8, 16, and 24 hr following the culture. The mature (MII) oocytes were subjected to in vitro fertilization (IVF) and the fertilization rate was assessed in three days.
Results: A significant difference was observed between the maturation rates in the hCCCM and control groups (24.16% vs 0%; p = 0.001), as well as morphologic changes between the two groups (p = 0.04, p = 0.05). The development rate for MII oocytes attained from IVM in the hCCCM group was 27.58% (2-cell) and 6.89% (4-cell). Data displayed that hCCCM is an effective medium for oocytes maturation compared to the control medium.
Conclusion: hCCCM supports oocyte in vitro growth and maturation. Moreover, hCCCM changes the oocyte shape and size of perivitelline space.
Key words: Germinal vesicle, Cumulus cell, Conditioned medium, In vitro fertilization, In vitro maturation, Oocyte.
Association of acne, hirsutism, androgen, anxiety, and depression on cognitive performance in polycystic ovary syndrome: A cross-sectional study
Authors: Mehrabadi Saeideh , Jahanian Sadatmahalleh Shahideh , Kazemnejad Anoshirvan , Moini Ashraf
Published: December 2020

Background: While polycystic ovary syndrome (PCOS) is often associated with psychological distress, its most frequent clinical characteristics include acne, hirsutism and increased level of androgen hormones.
Objective: To evaluate the level of depression and anxiety, hirsutism, acne, and level of androgen hormones in PCOS and control group and its association with cognitive function.
Materials and Methods: This cross-sectional study was conducted on 53 women with PCOS and 50 healthy women as a control group. Data were collected using a questionnaire including the samples’ demographic information, clinical features, clinical findings of hyperandrogenism, and the Beck Depression and Anxiety questionnaire. In addition, the acne and hirsutism levels of the subjects were evaluated using the global acne grading system and the Ferriman-Gallwey scoring system, respectively. The Montreal Cognitive Assessment (MoCA) is a screening test for cognitive impairment that covers major cognitive domains.
Results: A significant difference was found between the two groups in the mean levels of acne, hirsutism, total testosterone, free androgen index, depression, and anxiety. However, some mean values of the MoCA were lower in the women of case group compared to the control group. Additionally, a significant difference was observed between the two groups in the domains of visual-spatial ability (p = 0.009), executive function (p = 0.05), attention (p = 0.03), and total MoCA scores (p = 0.002).
Conclusion: The PCOS women demonstrated significantly lower performance on the tests of executive function, attention, and visual-spatial function than the healthy control women.
Key words: PCOS, Cognitive function, Androgen, Depression and anxiety.
Iranian temporal changes in semen quality during the past 22 years: A report from an infertility center
Authors: Vahidi Serajeddin , Reza Moein Mohammad , Yazdinejad Fatemeh , Ghasemi-Esmailabad Saeed , Narimani Nima
Published: December 2020

Background: Despite numerous reports about temporal changes in semen quality from all over the world, the debates continue. The latest systemic review has shown an overtime decrease in semen quality worldwide.
Objective: To assess the temporal changes in the semen quality among Iranian population referred to an infertility center.
Materials and Methods: In this retrospective cross-sectional study, semen parameters including concentration, motility, and morphology were compared between Iranian men reffered to Research and Clinical Center for Infertility, Yazd between 1990 to 1992 (group 1, n = 707) and 2010 to 2012 (group 2, n = 1108). Demographic characteristics and semen analysis were collected from the records. The effect of age on semen parameters was also investigated.
Results: Despite the increase in sperm concentration l in group 2, sperm with normal morphology decreased significantly (p < 0.001). Grade-A motility decreased (p < 0.001), grade B motility increased (p < 0.001), and grade C and D motile sperm remained constant (p = 0.303 and p = 0.315, respectively). Also, no significant correlation between the age and semen parameters were observed.
Conclusion: This study showed inconsistent temporal changes in the participant semen quality. Significant temporal decline were obtained between various semen parameters, sperm morphology and grade A motility. These results should be further evaluated by larger studies in the future.
Key words: Infertility, Semen quality, Temporal changes.
Radioprotective effect of a combination of melatonin and metformin on mice spermatogenesis: A histological study
Authors: Tajabadi Elham , Javadi Abdolreza , Ahmadi Azar Nasim , Najafi Masoud , Shirazi Alireza , Shabeeb Dheyauldeen , Eleojo Musa Ahmed
Published: December 2020

Background: The spermatogenesis system includes highly radiosensitive cells. Hence, this system is a potential target for toxic effects of ionizing radiation during radiotherapy of abdomen and pelvis cancers, as well as after accidental radiation events. Accordingly, metformin and melatonin are two important radioprotectors that have shown an ability to prevent cell death through neutralization of free radicals and stimulating DNA damage responses.
Objective: To evaluate the radioprotective effects of melatonin and metformin on mice spermatogenesis when administered alone or as a combination.
Materials and Methods: In this histological Study, 40 (6-8 wk, 30 gr) NMRI mice were divided into 8 groups (n = 5/each) as control, metformin, melatonin, melatonin + metformin, radiation, radiation + melatonin, radiation + metformin, and radiation + melatonin + metformin. 37 days after the irradiation, the testicular tissues were collected for histological evaluation.
Results: Single administration of melatonin could ameliorate effectively radiation toxicity in mice testis. Metformin showed radioprotective effects on some parameters such as the numbers of spermatogonia and mature sperms. Interestingly, the melatonin and metformin combination reversed the reduced number of sperms rather than single drug administration.
Conclusion: The combination of melatonin with metformin can protect mice spermatogenesis against ionizing radiation more effectively compared to the single forms of these drugs.
Key words: Radiation, Testis, Leydig cells, Melatonin, Metformin, Spermatogenesis.
Intraovarian insertion of autologous platelet growth factors as cell-free concentrate: Fertility recovery and first unassisted conception with term delivery at age over 40
Authors: Scott Sills E. , S. Rickers Natalie , Wood Samuel H.
Published: December 2020

Background: The use of autologous platelet-rich plasma as an ovarian treatment has not been standardized and remains controversial.
Case Presentation: A 41½-year old woman with diminished ovarian reserve (serum anti- Müllerian hormone = 0.163 mg/mL) and a history of 10 unsuccessful in vitro fertilization cycles presented for reproductive endocrinology consult. She and her partner declined donor oocyte in vitro fertilization. They were both in good general health and laboratory tests were unremarkable, except for mild thrombocytosis (platelets = 386K; normal range 150-379K) discovered in the female. The patient underwent intraovarian injection of fresh platelet-derived growth factor concentrate administered as an enriched cell-free substrate. Serum anti- Müllerian hormone increased by 115% within 6 wks of treatment. Spontaneous ovulation occurred the month after injection and subsequently the serum human chorionic gonadotropin was noted at 804 mIU/mL. Following an uneventful obstetrical course, a male infant was delivered at term without complication.
Conclusion: This is the first description of intraovarian injection of enriched platelet-derived growth factors followed by unassisted pregnancy and live birth. As a refinement of conventional ovarian platelet-rich plasma therapy, this procedure may be particularly valuable for refractory cases where prognosis for pregnancy appears especially bleak. A putative role for thrombocytosis is also viewed in parallel with mechanisms of action as advanced earlier. With continued experience in ovarian application of autologous platelet growth factors, additional research will evaluate laboratory protocol/sample preparation, injection technique, and patient selection.
Key words: Ovarian rejuvenation, Platelet-rich plasma, Cytokines, Infertility, IVF.
Histamine Level in Freshwater and Marine Fish Sold in Bulgarian Markets
Authors: Bangieva D. , Stratev D. , Stoyanchev T.
Published: December 2020

Background: Histamine is an essential biogenic amine produced as a result of microbial decomposition of histidine during seafood processing and storage. The objective of this study was to evaluate histamine concentration in freshwater and marine fish marketed in Stara Zagora region, Bulgaria.
Methods: Forty fish samples were purchased from local fish farms and retail stores in Stara Zagora, Bulgaria. Enzyme-Linked Immunosorbent Assay was used to determine histamine levels. The data were processed using GraphPad Software InStat 3.
Results: Histamine was detected in 26 out of 40 (65%) samples, and none of them exceeded the regulatory limit of 200 mg/kg. The average histamine content in marine fish (6.965±3.187 mg/kg) was insignificantly (p>0.05) higher than that in freshwater fish (4.503±1.133 mg/kg).
Conclusion: The results reveal low levels of histamine in freshwater and marine fish indicating their good quality. However, its presence in seafoods remains a major food safety problem that requires permanent regulation of histamine concentration in fish.
Monitoring of Genetically Modified Rice among Some Imported Rice Samples in Iran
Authors: Hosseini M.S. , Fallahzadeh H. , Hosseini S.S.
Published: December 2020

Background: Genetically Modified (GM) foods are produced using genetic engineering. This survey attempted to identify the presence of GM rice varieties among some imported rice samples in Iran.
Methods: From May to July 2016, a total of 50 samples of the imported rice to Iran were obtained, including 20 bulk rice samples from Bandar Abbas custom, Southern Iran and 30 retail rice samples from some commercial brands sold in the local markets of Yazd, Iran. Polymerase Chain Reaction was used to assess the GM varieties.
Results: None of the studied rice samples had the target genes related to GM products. 
Conclusion: This study indicated no evidence for presence of GM rice among some bulk and retail imported rice samples in Iran. Since marketing of GM rice is not legally permitted in Iran, more comprehensive studies must be designed with higher sample size in various provinces of country to achieve more detailed data about situation of GM rice in the Iranian markets.
Methods for Optimizing the Objects Detection Range by a Multi-Channel Optical-Electronic System
Authors: Anikyev A.A. , Baryshnikov N.V. , Zavarzin V.I.
Published: December 2020

The paper describes the possibilities of increasing the objects detection range by a multichannel optoelectronic system, which can be done in two ways: by choosing a statistical criterion for making a decision and by a rational design of the receiving optical system. When analyzing ways to increase the quality of processing the signals received by the system through heterogeneous channels, we found several ways to improve the quality of decisions made: at the algorithmic, functional or design levels. In this study, we chose the methods of channel integration at the algorithmic and constructive levels. Since the problem of multi-alternative object detection by several spectral channels is being solved, the Bayesian criterion for the search quality of the minimum average risk was chosen at the algorithmic level as the most appropriate. The search for the minimum average risk was carried out according to the characteristics of the object type. The choice of this criterion when evaluating signals from two spectral ranges provided a gain in the detection range of about 10 %. At the design level, the function of the ratio of irradiance on channels, e.g. passive infrared and laser radar channels, is nonlinear. To ensure the same value of the increase in the detection range for each channel, it is necessary to redistribute the threshold sensitivity of the channels. We opted for a method of equalizing the ranges by changing the transmission coefficients of the channels. The alignment of the light-energy characteristics of the channels at the design level leads to a gain in the detection range of scanned objects by 5--7 %
Plasma-Chemical Etching of Thin Silver Films for Applications of Plasmonics by Inductive-Coupled Argon Plasma
Authors: Filippov I.A. , Velikovskiy L.E. , Shakhnov V.A.
Published: December 2020

The study focuses on the processes of plasma-chemical etching of silver films for the manufacture of photonic elements --- nanoscale light sources, and examines the theoretical foundations of etching processes and the process of plasma formation in plasma-chemical etching facilities. We assessed the introduced technology when forming topological elements in thin films of silver metal, and identified key problems, such as redeposition and non-volatility of the material. The paper presents the results of simulating the etching process for several critical submicron sizes, and, based on the simulation results, shows the dependences of the etching rates on the power of the plasma sources. The focus is on the formation of holes to create a nanoscale light source. Both positive and negative properties of the plasma-chemical etching method using a source of inductive-coupled plasma are considered, and the features of technological facilities used for these processes are outlined. The process of formation of nanoelements in a silver film and the effect of redeposition of material particles as a result of ion sputtering are considered. We propose a two-stage etching process, which makes it possible to form a vertical profile of the walls of the manufactured elements and to avoid the effect of redeposition. We also give recommendations for the processes of etching through an electron-beam resist in facilities with an inductive-coupled plasma source. By optimizing the thicknesses of the resistive mask and plasma sources, we obtained the results of etching nanoscale elements with preservation of geometric shapes
Leveraging Context Awareness in Designing Mobile E-Government
Authors: Agbozo E. , Medvedev A.N.
Published: December 2020

In the age of ubiquitous computing, smart systems, internet of things, and numerous modern technological advances in the smartphone world, context-aware programming has made progress within the past decade. Google's Awareness API is a great example of the available power to developers for optimizing user experience of mobile applications. Electronic Government (e-government) solutions, primarily mobile-based, which stand to gain maximum utility should integrate such innovations. This study, supported by the PMJ (Perception--Memory--Judgment) cognitive computing model, integrates context-aware models into e-government design in order to increase e-participation and user experience with respect to public service delivery. The study has employed the ontological evaluation technique which is a recommended non-empirical method of evaluating information systems. The purpose of using this technique is validating potency of the model in the real-world. The study conceptualizes the model and verifies it by the non-empirical technique of ontological evaluation using Protege. This study simulates a scenario using C# and illustrates the feasibility of the model by considering user-privacy and system health
Research of the Processes of Chromatographic Analysis of Medicines on HKUST-1 Metal-Organic Framework Structures
Authors: Markova E.B. , Savchenko A.S. , Cherednichenko A.G. , Averina Yu.M. , Boldyrev V.S.
Published: December 2020

The paper studies the process of analysis of tetracycline and paracetamol with the use of the HKUST-1 organometallic framework sorbent by high performance liquid chromatography. To obtain experimental data using the previously described technique, a sample of the material under consideration was synthesized and its physicochemical properties were studied. It has been established that individual sorbent particles have an octahedral shape and have a porous structure capable of adsorbing chemical compounds of various nature. The specific surface of the sample was calculated using the BET method and was Ssp = 551.3 m2/g. The study notes that when water or aqueous-organic media are used as eluents for chromatographic analysis, sorbents based on HKUST-1 have low stability; their degradation is observed when passing eluent solutions in an amount equal to 300--500 volumes of the chromatographic column. When only organic solvents are used for chromatographic analysis of tetracycline and paracetamol in the temperature range of 25--45 °C, no decomposition of the HKUST-1 sorbent and no degradation of the analyzed drugs are observed. Findings of research show that the efficiency of the eluent increases in the tetrahydrofuran--methanol--acetonitrile series. For all organic solvents used, the retention times were determined, the degree of separation, HETP, and the speed of response were calculated at various temperatures. A complex of studies has proved the possibility of using the organometallic sorbent HKUST-1 for the effective separation of drug mixtures by high-performance liquid chromatography
Rheological Effects on Swelling of Polymer Membranes in Water
Authors: Bunkin N.F. , Bashkin S.V. , Juraev Y.T. , Safronenkov R.S. , Kozlov V.A.
Published: December 2020

The study focuses on rheological effects which appear during swelling of the Nafion proton-exchange membrane in cuvettes of different thicknesses, and explains the effects by the appearance of the so-called excluded zone near the membrane surface. The excluded zone is the polymer fibers of the Nafion membrane, deployed towards bulk water. The depth of fiber penetration into the volume or the size of the excluded zone depends on the deuterium content in the water. It should be noted that in the process of swelling of the Nafion membrane plate in water it is structurally rearranged, which leads to a transition from a hydrophobic state to a hydrophilic one. By means of experimental methods based on Fourier transform infrared spectrophotometry, the study shows that the swelling of the Nafion membrane plate, which is initially hydrophobic, in ordinary water (deuterium content is 157 ppm) and in deuterium-depleted water (deuterium content is 1 ppm) in a cuvette of limited volume occurs differently. Small changes in the deuterium content in water turned out to lead to significant differences in the dynamics of swelling of the polymer membrane. For a 175-micron-thick Nafion membrane plate, this effect is most evident when the distance between the cuvette windows is L = 200 microns
Gravitational and Coulomb Potentials Interference in Heliosphere
Authors: Vysikaylo P.I. , Ryabukha N.S.
Published: December 2020

Interference of gravitational and Coulomb potentials in the entire heliosphere is considered, it is being manifested in generation of two opposite flows of charged particles: 1) that are neutral or with a small charge to the Sun, and 2) in the form of a solar wind from the Sun. According to the Einstein --- Smoluchowski relation Te(R) = eDe / µe ~ (E/N)0.75 based on the N experimental values (heavy particles number density --- the ne electron concentration), the Te electron temperature in the entire heliosphere was for the first time analytically calculated depending on the charge of the Sun and distance to it R. Calculated values of the registered ion parameters in the solar wind were compared with experimental observations. Reasons for generating the ring current in inhomogeneous heliosphere and inapplicability of the Debye theory in describing processes in the solar wind (plasma with current) are considered
Investigation of dispersion and aerodynamic drag of modified bullets at subsonic flight speeds on a ballistic track
Authors: Ilukhin S.N. , Moskalenko V.O. , Bulavina V.V.
Published: December 2020

The purpose of the work was to experimentally research and analyze the effect of the proposed modifications of a pneumatic bullet on the accuracy parameters of the shooting system with a subsonic initial speed. The study introduces variants of modernization of a bullet with a flat head part for pneumatic weapons, describes the external ballistic experiments carried out on the ballistic track of the Department of Dynamics and Flight Control of Rockets and Spacecraft of Bauman Moscow State Technical University, and theoretically substantiates the physics of the interaction between a bullet and the air, which became possible after analyzing the results of shooting. The obtained correlation between scattering characteristics of unguided aircraft and the type of modification of their aerodynamic shape is described. On the basis of the data obtained, modifications of the bullet shape were determined, leading not only to a decrease in aerodynamic drag, but also to a certain decrease in dispersion during shooting.
Kallpachakuy: Coca, bebida y cigarro como fuerza y protección en la peregrinación a Qoyllurit´i
Authors: Torres Lezama Vicente
Published: December 2020

El objetivo de este trabajo es mostrar la noción que tienen los peregrinos de Qoyllurit´i y pobladores quechuas del sur peruano sobre la coca, la bebida y el cigarro. La investigación se sustenta en prácticas compartidas, entrevistas y diálogos con peregrinos, danzantes y pobladores del Cuzco desde el 2011 hasta el 2019. En esta experiencia peregrina aprendí que la coca y las bebidas como la chicha, la cerveza, el aguardiente, el cañazo, entre otros, son considerados fuerza o kallpa porque son capaces de activar a las personas e impulsarlos a realizar determinadas acciones como danzar con gusto, trabajar con ganas y hablar con fluidez. Pero no se limitan a la provisión de fuerza, sino que también son proveedoras de calor y protectoras de malos espíritus, entidades agresivas y malos vientos. La coca, la bebida y el cigarro tienen intencionalidad y son capaces de llevar a la acción a los sujetos.
Physicochemical and Microbiological Examination of Food Preservation Strategies of Indian Dishes Kalan and Gulab Jamun
Authors: Sreeraj J. , Madhavankutty K.G. , Anoop M.
Published: December 2020

Background: The curd curry commonly known as kalan in Kerala and Gulab Jamun has been chosen in the present work which is relevant in accordance with its usage with common man. Kalan possesses a normal shelf of two days at normal temperature and room conditions. The present work attempted to preserve the product for two weeks or more at room temperature by applying canning technique. The shelf life of Kalan was proved to be enhanced to two more weeks with proper canning. Kalan is prepared in the laboratory and was packed in sterile bottles which were then sterilized by dipping in sterile hot water for thirty minutes. This process impairs the product sufficient sterility to enhance the preserving quality considerably. The product has been found unchanged in its flavor and taste after the expected expiry period. In the preparation of Gulab jamun,drying and frying strategies facilitates the removal of most of the contaminants and hence the product presented as sterile. The sugar syrup provides further preservation. This technique for preservation can thus become effective. The work presented an attempt that has been made to study the effect of processing / preservation technique.Methods: Canning technique was applied as a preservation strategy to the product kalan and addition of sugar syrup presented to be the preservation technique for gulab jamun. Both were considered as the natural way of preservation rather than utilizing any artificial strategies or additions. The shelf life of the same was studied in detail under physiological, biochemical and microbiological parameters.Result: The two food preservation techniques studied in this project are proved to impart better shelf life to the particular type of dairy based products without the addition of any preservative chemicals.
Risk Tolerance Profiling Measure: Testing Its Reliability and Validities
Authors: Chung Wee Kang , Au Wing Tung
Published: December 2020

This study examines the degree to which the customer risk profiling measure (CRPM), commonly used by financial institutions to determine loss tolerance of investors, is psychometrically valid in assessing risk tolerance and predicting anxiety after experiencing a significant investment loss. Data were collected online from 91 respondents with various investment experience, Results suggest that CPRM is significantly correlated with the Grable and Lytton's Financial Risk Tolerance Scale (G/L-RTS), a validated financial risk tolerance measure. CPRM is also able to predict anxiety after experiencing a significant investment loss. Furthermore, CRPM also demonstrates incremental predictive validity above and beyond G/L-RTS in predicting anxiety after investment loss.
Generalized Self-Similar First Order Autoregressive Generator (GSFO-ARG) for Internet Traffic
Authors: Popoola Jumoke , Yahya Waheed Babatunde , Popoola Olusogo , Olaniran Oyebayo Ridwan
Published: December 2020

Internet traffic data such as the number of transmitted packets and time spent on the transmission of Internet protocols (IPs) have been shown to exhibit self-similar property which can contain the long memory property, particularly in a heavy Internet traffic. Simulating this type of dataset is an important aspect of delay avoidance planning, especially when trying to mimic real-life processing of packets on the Internet. Most of the existing procedures often assumed the process follows a Gaussian distribution, and thus long memory processes such as Fractional Brownian Motion (FBM) and Fractional Gaussian Noise (FGN) among others are used. These approaches often result in estimation errors arising from the use of inappropriate distribution. However, it has been established that the distribution of Internet processes are heavy-tailed. Therefore, in this paper, a new method that is capable of generating heavy-tailed self-similar traffic is proposed based on the first-order autoregressive AR (1) process. The proposed method is compared with some of the existing methods at varying values of the self-similar index and sample sizes. The imposed self-similarity indices were estimated using the Range/Standard deviation statistic (R/S). Performance analysis was achieved using the absolute percentage errors. The results showed that the proposed method has a lower average error when compared with other competing methods.
“Der Emes”: newspaper, printing house, publishing house
Authors: Khazdan Sofia E.
Published: December 2020

Many Russian, Soviet and foreign Russian-­language publications since 1882 were called “Pravda”. Some of them (the newspaper, the printing house and the publishing house) had a similar name in Yiddish containing Hebraism – “Der Emes”. The main problem of the research is to identify interaction points of these organizations. The purpose of this study isto find out how these print media relate to each other. The author considers their history on the basis of archival documents and memoirs of employees of these institutions. The analysis of publishing production was carried out on materials of the bulletin of the Russian Book Chamber and collections of Jewish publications found in two main libraries of Russia. The author has identified several printing houses with the same name of different subordination, working with printed products in Yiddish and Russian. The author came to the conclusion that the newspaper editorial board, the Printing house and the Publishing house “Der Emes” were in close cooperation.
Speciality 05.25.03 “Library science, bibliography and book science”. What are the prospects?
Authors: Brezhneva Valentina V. , Dvorkina Margarita Ya. , Kalegina Olga A. , Lopatina Natalya V. , Stolyarov Yuri N.
Published: December 2020

The material presents the views of the chairs and members of the dissertation councils at the KazGIK, MGIK, SPGIK and RSL on the specialty 05.25.03 indicated in the title on four issues: 1. Are you confident in the future of your dissertation council? What is your confidence or anxiety related to? 2. What do you think are the problems of modern library science, bibliography and book studies? 3. There are only 4 dissertation councils on the specialty – 03.25.03 – in Russia: in Kazan, Moscow, St. Petersburg, Khimki. Do you think this is sufficient for the development of our industry? 4. What question (s) on the dissertation council would you like to be asked?

The answers showed concern for the future of not only of dissertation counsils as such, but confirmed serious concerns about the future of the specialty 05.25.03.
Surgical Treatment of Distal Radial Fractures with External Fixation Versus Volar Locking Plate
Authors: Ludvigsen Trine , Matre Kjell , Gudmundsdottir Rakel Sif , Krukhaug Yngvar , Dybvik Eva Hansen , Fevang Jonas Meling
Published: December 2020

Background:

The use of volar locking plate fixation (VLP) for unstable extra-articular distal radial fractures has increased in the last decades. External fixation (EF) is less frequently used. This change of surgical approach has only to some extent been evidence-based.

Methods:

In this multicenter, randomized controlled trial, we compared VLP and EF in patients between 18 and 70 years of age who had a displaced extra-articular distal radial fracture (OTA/AO type A3). The patients were examined at 6 weeks, 3 months, and 1 year postoperatively. The primary outcome measure was the Patient-Rated Wrist/Hand Evaluation score (PRWHE). Secondary outcomes were the shortened version of the Disabilities of the Arm, Shoulder and Hand (QuickDASH), pain score on a visual analog scale (VAS), and radiographic measurements. Range of motion, grip strength, finger stiffness, complications, and reoperations were also recorded.

Results:

One hundred and fifty-six patients were included. One hundred and forty-two (91%)—127 women (89%) and 15 men (11%)—completed 1 year of follow-up. Sixty-nine patients were treated with VLP and 73, with EF. The mean age was 56 years. At 6 weeks, the median PRWHE score was significantly higher in the EF group (44) compared with the VLP group (27) (p < 0.001). At 3 months and 1 year, the difference between groups was not significant. The median QuickDASH score was 27 in the VLP group and 43 in the EF group at 6 weeks (p < 0.001), and a significant difference persisted at 3 months (p = 0.023). The VLP group had superior results in terms pain during activity, wrist extension, and ulnar and radial deviation at 1 year, whereas the number of major complications was similar in the 2 groups.

Conclusions:

Patients treated with VLP had earlier recovery of function compared with patients treated with EF. One year postoperatively, we found no significant functional difference.

Level of Evidence:

Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
Clinical and Health-Care Cost Analysis of Negative Pressure Dressing in Primary and Revision Total Knee Arthroplasty
Authors: Yaghmour Khaled M. , Hossain Fahad Siddique , Konan Sujith
Published: December 2020

Background:

Negative pressure wound therapy (NPWT) has been used because of its perceived advantages in reducing surgical site infections, wound complications, and the need for further surgery. The purpose of this study was to assess the infection rates, wound complications, length of stay, and financial burden associated with NPWT use in primary and revision total knee arthroplasty (TKA).

Methods:

We performed a PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) systematic review of the existing literature on using NPWT in primary and revision TKA. PubMed, Embase, Science Direct, and the Cochrane Library were utilized. The risk of bias was evaluated using the ROBINS-I (Risk Of Bias In Non-randomised Studies - of Interventions) tool, and the quality of evidence was evaluated using the GRADE (Grading of Recommendations Assessment, Development and Evaluation) criteria.

Results:

Twelve articles that evaluated 1,403 primary TKAs and 279 revision TKAs were reviewed. NPWT significantly reduced complication rates in revision TKA. However, there was no significant difference in infection rates between NPWT and regular dressings in primary or revision TKA. NPWT use in primary TKA significantly increased the risk of blistering, although no increase in reoperations was noted. The analysis showed a possible reduction in length of stay associated with NPWT use for both primary and revision TKA, with overall health-care cost savings.

Conclusions:

Based on a meta-analysis of the existing literature, we do not recommend the routine use of NPWT. However, in high-risk revision TKA and selected primary TKA cases, NPWT reduced wound complications and may have health-care cost savings.

Level of Evidence:

Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Occurrence of L4 Lumbar Artery Pseudoaneurysm After Posterior Reduction and L4-L5 Fusion for Grade I Anterolisthesis
Authors: Ruffilli Alberto , Barile Francesca , Fiore Michele , Pasini Stefano , Facchini Giancarlo , Faldini Cesare
Published: December 2020

Case:

We describe the case of a 53-year-old man who developed acute groin pain 20 days after a posterior L4-L5 interbody fusion. Despite positioning of pedicle screws within the safe zone, an L4 right lumbar artery pseudoaneurysm was found on computer tomography angiogram. Coil embolization was successfully performed.

Conclusion:

Iatrogenic lumbar artery pseudoaneurysms are a rare complication of spinal surgery. Our case is, to the best of our knowledge, the only reported case where this lesion occurred despite good positioning of the screws: It is therefore important to always suspect and exclude this complication in case of suggestive symptoms.
Resect or Retain Bone Fragments in Children and Teenagers with Severe Open Fractures?
Authors: Rölfing Jan Duedal , Bue Mats , Kiil Birgitte , Petruskevicius Juozas
Published: December 2020

Case:

A 14-year-old pedestrian was hit by a car and encountered similar bilateral Gustilo IIIB open tibial fractures. The right tibial fracture involved a large borderline vital butterfly fragment without periosteal contact, which was retained and proceeded to sufficient healing within 12 weeks. The left tibial fracture was treated according to the principles for the treatment of severe open fractures in adults, involving resection of devitalized fragments and bone transport, and healed within 15 months.

Conclusions:

Teenagers do possess larger bone healing potential than adults. Therefore, a rapid bone union can be achieved even with apparently devitalized bone fragments if sufficient soft-tissue closure and stable fracture fixation is established early in the treatment of open limb fractures.
Surgical Technique for Anterior Approach for Total Hip Arthroplasty After Bilateral Below-Knee Amputation
Authors: Mahmood Mustafa , Samuel Linsen T. , Kamath Atul F.
Published: December 2020

Case:

We report a case of a 77-year-old man, with bilateral below-knee amputee, in whom the anterior approach (AA) for a left total hip arthroplasty was used successfully, with 3-year follow-up. This report also summarizes the key studies in the literature on this subject.

Conclusions:

The utility of AA surgery performed in the setting of bilateral below-knee amputation has not been previously described. We describe the surgical technique, including considerations and pearls in the amputee population, and particular technical tips related to the use of a fracture table and thin-wire femoral traction for optimum control of the residual limb.
The Integration of Religious Moderation Values in Islamic Religious Education Learning at Public Universities (Efforts and Constraints in the Implementation of Anti-Radicalism Education)
Authors: Herlinawati Herlinawati
Published: December 2020

The development of radical understandings and attitudes that also penetrate the campus world that needs to be addressed by including religious moderation and understanding of Islamic Religious Education (IRE) learning in Public Universities in the framework of implementing anti-radicalism education in IRE learning in Public Universities. This study aims to see the integration of moderation values in IRE learning in public universities in the application of anti-radicalism education, as well as what alarms are the obstacles. The approach used in this study is a descriptive qualitative approach, with the analysis stages in the form of data reduction, data presentation and conclusion drawing. The results showed that first, the values of religious moderation have been integrated in the learning of IRE in Public Universities through materials related to tolerance, brotherhood (ukhuwah), and the concept of Islamic teachings as a religion of rahmatan lil 'alamin. Second, the implementation of anti-radicalism education in IRE learning at public universities is seen from the content of the Semester Learning Plan (SLP) and Subject Learning Outcomes (SLO), most of the respondents have formulated it, only a small part is not specifically. There are several relationships that exist in the implementation of anti-radicalism education related to reference materials, time, and learning media.
Does intra-articular injection of adipose-derived stem cells improve cartilage mass? A case report on a 3D MRI quantitative evaluation of cartilage in knee osteoarthritis using SYNAPSE VINCENT: a case report
Authors: Kuwasawa Ayano , Nihei Kotaro
Published: December 2020

Background: Mesenchymal stem cells (MSC) are currently in focus because of the possibility of cartilage regeneration through several ways, including MSC sheets. However, there is no published report that visualizes cartilage in three dimensions. Here, we report a case of improved cartilage volume. We purified and cultured adipose-derived mesenchymal stem cells (ASC) and then performed ASC therapy by directly injecting these cells into the articular cartilage. Cartilage was quantitatively evaluated before and after injection using a three-dimensional (3D) image analysis software based on the MRI imagery.Case presentation: The patient, a 55-year-old woman, experienced pain in both knees and was diagnosed with osteoarthritis of the knee. We performed ASC therapy in both knees at our hospital and quantitatively evaluated cartilage before and after the treatment using the 3D image analysis software “SYNAPSE VINCENT”.Conclusions: For the quantitative analysis of cartilage, SYNAPSE VINCENT visualizes the state of cartilage in a high-definition 3D image, which is excellent for understanding the state of the disease and explaining it to the patient. Though there is room for debate about the reproducibility of errors, etc., SYNAPSE VINCENT would be useful as a clinical tool for regenerative medicine.
Calophyllum inophyllum, eine wenig bekannte Öl-Pflanze
Authors: Zahorka Herwig
Published: December 2020

Indonesien begann im März 2010 mit einem Bio-Diesel Pilotprojekt auf der Insel Madura. Auf 10 000 ha wird der dort an den Küsten heimische Baum Calophyllum inophyllum (indon. Nyamplung) angebaut. Die Samen enthalten 50-74% Öl, das zu Bio-Diesel verarbeitetwerden kann. Probefahrten mit diesem Treibstoff über einige 1000 km verliefen erfolgreich. Die Erzeugerkosten wurden bisher mit 4000 RP (etwa 30 Cent) je Liter berechnet. Der Baum und seine Nutzungsmöglichkeiten werden vorgestellt.
Giardino Garibaldi in Palermo
Authors: Steinecke Hilke , Schubert Peter
Published: December 2020

Der Garibaldi-Garten ist ein kleiner Stadtpark in der Altstadt von Palermo/Sizilien. Der Park weist einen alten Baumbestand auf. Am beeindruckendsten sind drei riesige Feigenbäume (Ficus macrophylla) mit zahlreichen, dicken Luftwurzeln. Einer von ihnen gehört zusammen mit dem gewaltigen Feigenbaum im Botanischen Garten von Palermo zu den größten Ficus-Bäumen in Europa.
Bananen (Musa-Arten) – Riesenstauden mit Zier- und Nutzwert
Authors: Dörken Veit Martin
Published: December 2020

Bananenpflanzen sind tropische Riesenstauden, die wichtige Obstlieferanten und attraktive Solitärpflanzen darstellen. Die winterharte Musa basjoo eignet sich auch in Mitteleuropa zur Freilandkultur, wo sie im Sommer gigantische Blütenstände und auch Früchte hervorbringen kann.
Bitterorange – bitter schmeckend und erfrischend duftend
Authors: Dörken Veit Martin , Höggemeier Annette
Published: December 2020

Die Bitterorange (Citrus trifoliata, früher Poncirus trifoliata) ist die einzige Citrus-Verwandte, die sich auch in klimatisch begünstigten Lagen Deutschlands als recht frosthart bewährt hat. Sie blüht und fruchtet auch hier regelmäßig und ist damit ein außergewöhnlicher Solitärstrauch auch für kleinere Gärten.
Paulownien – attraktive Nutzhölzer und Wappenbäume
Authors: Dörken Veit Martin , Steinecke Hilke
Published: December 2020

Paulownia tomentosa (Blauglockenbaum) ist ein beliebter Parkbaum. Biologie, Verwendung als Zierbaum, Nutzung des Holzes und Symbolik werden erläutert.
Spannendes über das Purpur-Knabenkraut, Orchidee des Jahres 2013
Authors: Baumann Kurt
Published: December 2020

Das Purpur-Knabenkraut (Orchis purpurea) ist Orchidee des Jahres 2013. Biologie und Ökologie werden erläutert. Hybriden mit anderen Orchideen werden genannt.
Oxalis deppei, Glücksklee für die Fensterbank
Authors: Buch Corinne
Published: December 2020

Oxalis deppei wird häufig als Glücksbringer verschenkt. Die Knollen lassen sich leicht weiter kultivieren. Biologie, Symbolik und Kultur des Glücksklees werden vorgestellt.
Frühling im Nationalpark Pollino
Authors: Steinecke Hilke , Schubert Peter
Published: December 2020

Der Nationalpark Pollino liegt am südlichen Ende des Apennins in Kalabrien. Wappenpflanze des Nationalparks ist die seltene Panzer-Kiefer (Pinus heldreichii), die dort noch mit 1000-jährigen Individuen erhalten ist. Zudem erstrecken sich im Nationalpark ausgedehnte Buchen-Urwälder, in denen Wölfe, Bären, Luchse und Wildkatzen vorkommen. Im Frühling blühen auf den artenreichen Bergwiesen stellenweise viele Orchideen, Narzissen und Veilchen. Flora, Vegetation und Landschaft des Nationalparks werden vorgestellt.
Zitruspflanzen-Sammlung im Wiener Schloss Schönbrunn
Authors: Becker Alexander
Published: December 2020

Eine der bekanntesten Orangerien Europas ist diejenige in Wien-Schönbrunn. Die Geschichte der kaiserlichen Wiener Zitrussammlung sowie die Architektur des Gebäudes werden kurz vorgestellt.
Es stinkt! Komponenten im Blütenduft von Orchidantha fimbriata
Authors: Feulner Martin , Lauerer Marianne , Dötterl Stefan
Published: December 2020

Im Dezember 2014 blühte im Ökologisch-Botanischen Garten der Universität Bayreuth Orchidantha fimbriata Holttum (Lowiaceae), deren bodennah stehende, große Blüten unangenehm, kotähnlich stinken. Dies war Anlass, Duftproben von einzelnen Blütenteilen (Labellum, Labellum plus Griffel-Staubblatt-Apparat, Sepalen) zu sammeln. Die Auswertung der Proben mittels Gaschromatographie gekoppelt mit Massenspektrometrie (GCMS) ergab, dass für die unangenehme Note des Duftes die Stoffe Dimethyldisulfid, p-Cresol sowie Indol verantwortlich sind. Diese Substanzen sind bereits aus anderen Kot oder Aasdüfte nachahmenden Pflanzenarten wie einigen Araceae und den Stapelien bekannt. Zudem enthielt das Duftbouquet neben einer großen Anzahl von Sesquiterpenen eine Reihe von Fettsäureestern, die dafür bekannt sind, Fruchtkäfer anzulocken.
Botanische Streifzüge durch die Souks marokkanischer Königsstädte
Authors: Steinecke Hilke
Published: December 2020

Ein Streifzug durch die historischen Einkaufsviertel der marokkanischen Königsstädte Rabat, Meknès, Fès und Marrakesch ist sehr lohnenswert. Viele bei uns nicht unbedingt überall erhältliche und deshalb auch teilweise unbekannte Pflanzen und Pflanzenteile werden hier als Nahrungsmittel, Duftstofflieferant oder Heilmittel angeboten. Andere liefern Ausgangsstoffe für Gewebe, Flechtarbeiten, Textilfarben oder diverse kunsthandwerkliche Produkte. Typische Waren, die es in den vielen marokkanischen Geschäften sowie auf Marktständen zu kaufen gibt, werden in Hinblick auf ihre botanischen Aspekte vorgestellt.
Linden, wichtige Nutz- und Ziergehölze mit langer kulturhistorischer Tradition
Authors: Dörken Veit Martin , Steinecke Hilke , Zündorf Ilse
Published: December 2020

Winter- und Sommer-Linden sind bei uns heimische Bäume. Diese sowie andere Linden sind wichtige Nutz- und Ziergehölze. Das Pflanzen von Linden im Zentrum von Dörfern, an Höfen oder an Kapellen hat bei uns eine lange Tradition. Beliebt sind Linden nicht nur wegen ihres süßen Blütenduftes, dem von ihnen stammenden milden Lindenhonig oder der Verwendung als Heilpflanze. Die Biologie verschiedener Linden-Arten, ihre Nutzung, Kulturgeschichte sowie das Hummelsterben unter Linden werden angesprochen. Wegen ihrer großen kulturellen Bedeutung in Mitteleuropa wurde die Winter-Linde (Tilia cordata) zum Baum des Jahres 2016 gekürt. Die Sommer-Linde (Tilia platyphyllos) war bereits 1991 Baum des Jahres.
Uncarina-Sammlung im Palmengarten
Authors: Steinecke Hilke
Published: December 2020

Der Palmengarten beherbergt eine gute Uncarina-Sammlung. Diese wird kurz vorgestellt.
Klatsch-Mohn (Papaver rhoeas): Blume des Jahres 2017
Authors: Jagel Armin
Published: December 2020

Der Klatsch-Mohn ist Blume des Jahres 2017. Als früher häufiges Ackerunkraut ist er bei uns selten geworden. Er kommt aber noch immer an Ersatzstandorten wie Straßenrändern, Böschungen oder Baustellen vor. Der Mohn hat vielseitige Verwendungsmöglichkeiten als Farb,- Heil- oder Zierpflanze. Seine Biologie, Morphologie, Verwendungsmöglichkeiten und Symbolik werden vorgestellt.
Rot-Fichte (Picea abies), Baum des Jahres 2017
Authors: Dörken Veit Martin
Published: December 2020

Die Rot-Fichte (Picea abies) ist Baum des Jahres 2017. Da sie ein wichtiger Nutzholzbaum ist, wird sie in unseren Forsten bevorzugt gepflanzt, oft auch in Monokulturen. Früher war die Rot-Fichte auch der klassische Weihnachtsbaum. Neben verschiedenen Nutzungsmöglichkeiten werden Verbreitung, Morphologie und Biologie dieses Nadelbaumes vorgestellt.
Flora an der Chinesischen Mauer bei Jiankou
Authors: Miller Eva
Published: December 2020

Die Chinesische Mauer ist seit 1986 anerkanntes Weltkulturerbe und seit jeher eines der identitätsstiftenden Wahrzeichen Chinas. Sie führt in weiten Teilen durch abgelegene und bisweilen schwer zugängliche Gebiete. Dieser Artikel beschäftigt sich mit der Vegetation an und auf dem Mauerabschnitt von Jiankou in der Nähe von Peking, der verhältnismäßig gut zu erreichen, jedoch nicht touristisch erschlossen ist.