bluuebunny/crossref_metadata_2025 huggingface dataset:
E-Leadership: Lessons Learned from Teleworking in the COVID-19 Pandemic
Authors: Mourão Luciana , da Silva Abbad Gardênia , Legentil Juliana
Published: November 2021

During the pandemic crisis, teleworking was compulsory for many workers, without the time and conditions to organize themselves for this transition. Therefore, the leadership needs to respond quickly to changes that occur in times of crisis—such as the current pandemic—adjusting its competencies to prioritize the well-being of employees, define performance goals, follow-up on these goals, provide guidance and support teleworkers, and improve feedback processes. The present study aims to propose an e-leadership theoretical model based on lessons learned from the coronavirus pandemic. To that end, we describe and discuss a survey on the perceptions of support received from managers during the initial 3 months of the pandemic. For this purpose, we collected data with 7608 workers distributed to 95 public service organizations in Brazil. In addition, we also reviewed several empirical studies that assessed the role of leadership in the proper functioning of telework. The support of leaders is directly associated with the theory of organizational support. In moments of crisis like the current one, this focus on leadership is even more critical. Thus, we present a theoretical model for e-leadership that should expand from the telework experiences during the coronavirus pandemic.
Fabricating Natural Biocomposites for Food Packaging
Authors: Hamid Liqaa , Samy Irene
Published: November 2021

Nowadays, there are dominant scientific breakthroughs to advance the packaging industry to identify innovative and emerging fruitful results for making the food packaging systems, in particular, more efficient, resilient, and sustainable. Therefore, friendliness packaging research has been gaining momentum, thanks to global environmental awareness, and also consumer ecological consciousness, and leading companies are committing to a more holistic worldview of packaging in response to more sustainable processes to reduce pollution and any depletion of resources. High-yielding and cost-effective production and design of packaging, involving synthetic materials use reduction and development of new bio-based packaging materials, are very much part of this holistic approach. Thus, in comparison with petroleum-based materials, potential bio-based materials may have benefits for all agents comprised: the producers, customers as well as the whole environment. This chapter explores a review of relative topics across all disciplines that could accelerate understanding toward this goal. It walks through conventional materials, and then important natural and synthetic polymers from the context of food packaging. Moreover, it provides an overview of the performance of bioplastics and their limitations. State-of-the-art main trends on green biocomposites thereof, their potential to transform the food industry, are also herein considered.
Empowering Professional Competence and Moral Responsibility for Corporate Sustainability: Insights from Industry and University Strategic Alliance
Authors: Huda Miftachul , Ahmad Roslee , Aderi Che Noh Mohd , Hashim Azmil , Hairy Ibrahim Mohd , Mohd Nasir Badlihisham , Suhaila Ahwani Siti , Saleh Rosman Arief , Mohd Zaim Bin Ab Rahim Nik , Munirah Abd Razzak Monika
Published: November 2021

The stability of corporate sector is definitely related to the prominent firms’ conditions, where both inner and outer factor played a significant role in enhancing the value proportion in sustaining the existence. Although many was conducted in the outer part in the corporate sector, however, less attention was apparently being given to the internal point where professional and moral basis is needed for further exploration in giving insights into corporate sustainability. This chapter attempts to examine the insightful value of professional competence and moral responsibility to give the significant point in disseminating the enhancement of corporate sustainability. The literature review was carefully conducted from the referred articles: journals, books and conference proceedings on the related topic. The finding reveals that the insightful value of professional competence and moral responsibility in advancing the corporate sustainability could be achieved in particular point through industry and university alliance. The basis of this alliance of both could give insights into incorporating the particular model of strategic partnership along with the corporate social responsibility. Engaged through the higher education (HE) together with firm involvement, this aim refers to advance in achieving the quality balance on corporate social responsibility. As such, this study is expected to contribute in advancing the research development agenda on enhancing strategic partnership assigned between professional competences together with moral responsibility.
Anemia during Pregnancy and Its Prevalence
Authors: Zulkifal Sehar , Sarwar Shumaila , Saddique Madiha , Yaqoob Khalida , Muneer Arshia , Fatima Aisha , Kabir Ayesha , Asad Mangat Muhammad , Mateen Laiba , Javed Zeeshan , Manzoor Maleeha
Published: November 2021

Anemia is a serious health issue throughout the world affecting both sexes of any age group. This nutritional disease is more common among the pregnant women of developing countries, where it is a major cause of maternal death and negative outcome of pregnancy. Among all anemic types, IDA is most prevalent one and is comprises of about 95% of all anemic cases around the world. In many developing countries it is more common in women of low socio-economic background and with no record of antenatal checkup. There is need for further health educational programs to overcome anemia especially for pregnant females.
Patellofemoral Instability
Authors: V. Patel Deepak , M. Dávila Castrodad Iciar , Kurowicki Jennifer , K. McInerney Vincent , J. Scillia Anthony
Published: November 2021

Recurrent patellofemoral instability is a common cause of knee pain and functional disability in adolescent and young adult patients, resulting in loss of time from work and sports. There are numerous factors that contribute to recurrent patellofemoral instability; these factors include tear of the medial patellofemoral ligament (MPFL), weakening or hypoplasia of the vastus medialis obliquus (VMO), trochlear dysplasia, increased tibial tuberosity-trochlear groove (TT-TG) distance (>20 mm), valgus malalignment, increased Q angle, malrotation secondary to internal femoral or external tibial torsion, patella alta, and generalized ligamentous laxity. A detailed history and a thorough physical examination are crucial to clinch an early, accurate diagnosis. Imaging studies play an important role to confirm the clinical diagnosis and also help to identify concomitant intra-articular pathologies. Initially, nonoperative management (including the use of physical therapy, patellar taping or brace) is offered to patients with acute, first-time patellar dislocations and most patients respond well to this mode of treatment. Surgical treatment is indicated for patients who have post-trauma osteochondral fracture or loose body; predisposing anatomical risk factors; recurrent, symptomatic instability; and who have failed an adequate trial of nonoperative management. Surgical treatments include MPFL reconstruction, proximal or distal realignment procedures, and trochleoplasty. Lateral release is often performed in combination with other procedures and seldom performed as an isolated procedure. An individualized case-by-case approach is recommended based on the underlying anatomical risk factors and radiographic abnormality.
Life Expectancy and Healthy Life Expectancy of Adults in Oman: Does Women’s Longer Life Expectancy than Men Mean Success or Burden for Women?
Authors: Islam M. Mazharul
Published: November 2021

Objectives: The objective of this study was to examine the life expectancy (LE) and healthy life expectancy (HLE) of Omani adults with age and gender differentials, focusing on whether the higher LE of women than men is a gain or burden for women.
Method: Data for the study come from multiple sources such as the 2010 population census, the 2008 World Health Survey in Oman, and secondary data published in the Statistical Yearbook of Oman. The life table and the modified life table proposed by Sullivan were used for estimating the LE and HLE of adult people of age 20 and above, respectively.
Results: LE in Oman reached 76 years for both sexes in recent times. However, since 2010 LE has been stalled in the vicinity of 76 years in Oman. Women had higher LE than men (79 years versus 74 years). In terms of HLE, men outweighed women in Oman. At the age of 20, the gap between male-female LE was found to be 4.7 years in favor of females, whereas the gap between male-female HLE was found to be 5.8 years in favor of males. Females spent a relatively long time in poor health status than males (20.8 years versus 10.8 years) and the proportion of life spent in poor health was greater for females than males (35.0% vs. 19.3%). This revealed the paradox of less mortality but higher morbidity among women, supporting the “Failure of Success” hypothesis.
Conclusion: Appropriate health policy and strategy need to be taken to reduce the gender gap in LE and HLE in Oman.
The Artist's Hand
Authors: Peter Grace
Published: November 2021

This paper explores the power of portraits and their ability to redefine race and identity in time. In times of exploitation and disregard, black culture has been defined by the lends and hands of others. However, the emergence of black artists is now bringing light to a more personal perspective of their identity and culture. Artists such as Gayl Jones in her book Corregidora, Oneika Russell's new Olympia 7, and John B. Martin's Portrait of James Armistead Lafayette create and redefine a people who tried to be erased. Through these self-portraits, the importance of art and its creator are brought to life.
INTEGRATION OF INTERNET OF THINGS AND BLOCKCHAIN TO INCREASE HUMANITARIAN AID SUPPLY CHAINS PERFORMANCE
Authors: ARIAS ARANDA DANIEL , MOLINA FERNANDEZ LUIS MIGUEL , STANTCHEV VLADIMIR
Published: November 2021

This paper provide an overview of the benefits that the integration of IoT and Blockchain can produce on the Humanitarian Aid Supply Chain (HASC). Consdering the large number of partner involved in HASC, traditional centralized information systems become very vulnerable. In the same sense, the lack of mutual knowledge obstruct the needed cooperation. The joint use of IoT and Blockchain can overcome these problems. Main benefit as well as barriers to this implementation is analyzed, considering the diferent phases of the HASC.

KeywordsCovid19, Blockchain, Supply Chain Management, Internet of Things, Humanitarian Supply Chain
REGULATION OF SHARED ELECTRIC KICK-SCOOTERS IN THE MOST POPULATED SPANISH CITIES
Authors: BAEZA MUÑOZ MARIA DE LOS ANGELES , PEREZ DOVAL JOSE MARIA , GONZALEZ SARMIENTO JUAN NICOLAS , MAGRO VASSALLO JOSE MANUEL
Published: November 2021

The use of the electric kick-scooter is spreading more and more to different countries of the world. Some articles have recently been published on its implementation in some cities, especially in the United States. However, there is still little research on regulatory issues. This work studies the regulation of this new form of mobility in Spain. After analyzing the regulations approved in cities with more than half a million inhabitants, the differentiating regulatory factors between them have been determined. Using a cluster analysis, groups of cities have been established based on their normative similarity. The results obtained will contribute to making the use of this new form of mobility more efficient and sustainable.
MATHEMATICAL MODELS FOR BUFFER SIZING PROBLEMS IN PARALLEL ASSEMBLY LINES WITH MULTI-LINE STATIONS AND DIFFERENT CYCLE TIMES
Authors: AGUILAR GAMARRA HARRY , GARCIA VILLORIA ALBERTO , PASTOR MORENO RAFAEL
Published: November 2021

In industry there are production systems consisting of more than one assembly line. If these are close together, it is possible for an operator to perform tasks from two adjacent lines assigned to his station (this will be a "multi-line station")
MOŽDANA FILTRACIJA U KOMUNIKACIJI
Authors: Tanasić Branislav R.
Published: November 2021

Savremeni čovek je svakodnevno izložen brojnim i raznovrsnim informacijama. Mozak se od najezde poruka brani filtriranjem, odnosno aktivira mehanizam kojim se vrši trijaža informacija; prigušuju se sadržaji koji ne privlače pažnju ili u potpunosti potiskuju, dok se interesantni inputi stavljaju u fokus pažnje, čak se mogu pojačati. Ovaj proces je veoma važan jer se samo sadržaji koji su predmet pune pažnje memorišu, ostali podražaji prolaze nezapaženo kao da se nisu desili. Kako to ljudski mozak reaguje kao urođeni Adblocker? Kada korteks primi neku vrstu informacije koju smatra prioritetnom, šalje povratni signal delu poznatom kao talamički retikularni nukleus-TRN. U saradnji s asocijativnim korteksom (preko talamokortikalno-talamičke petlje), talamus može obaviti modulaciju primljene informacije povećanjem esencijalnih signala. Mozak mora neprestano da vrši filtraciju važnih, odnosno sadržaja koji su interesantni, od nebitnih, ometajućih interferenci. Stoga treba imati na umu da se memorišu samo sadržaji koji su interesantni i koji vezuju punu pažnju.
ANALIZA SPOLJNOTRGOVINSKOG BILANSA BOSNE I HERCEGOVINE
Authors: Šušnjar Čanković Vanja , Agić Zorana
Published: November 2021

Spoljnotrgovinski bilаns jedаn je od izuzetno vаžnih, а često i nаjvаžnijih segmenаtа plаtnog bilаnsа. Usljed visoke otvorenosti, ali slabe razvijenosti privrede, te niske konkurentnosti, Bosna i Hercegovina bilježi kontinuiran deficit u spoljnotrgovinskoj razmjeni sa svijetom. Glavni uzrok deficita tekućeg računa i u 2018. godini je značajan debalans u spoljnotrgovinskoj razmjeni robe. Posmatrajući period od posljednjih pet godina, možemo uočiti da Bosna i Herecegovina ostvaruje stabilnu stopu rasta ukupne robne razmjene, kako izvoza, tako i uvoza. Međutim, pokrivenost uvoza izvozom je i dalje nedovoljna. Samim tim, i spoljnotrgovinski deficit bilježi rast i to od 3,4% u odnosu na prethodnu godinu. Loš spoljnotrgovinski bilans bi se mogao regulisati pojedinim necarinskim barijerama ili supstituisanjem domaćih proizvoda za šta je neophodna jasno definisana i usaglašena strategija.
ISHODI UČENJA U OBRAZOVNOM I RADNOM KONTEKSTU
Authors: Macura Rajko , Novaković Nenad , Vujović Slavoljub
Published: November 2021

Savemeno društvo se susreće sa problemom neodgovarajućih kompetencija na tržištu radne snage. Ovaj problem je uglavnom uzrokovan nedostatkom adekvatnih i konzistentnih ishoda svršenih učenika i studenata. Predmet istraživanja je aktuelna problematika upotrebe ishoda učenja i razvoja potrebnih kompetencija u savremenom svijetu, u kontekstu kvaliteta nastavnog procesa. Cilj rada je da se stekne potpuniji uvid u pojmove ciljevi učenja, ishodi učenja i kompetencije. Ovi pojmovi se često miješaju,te ih je potrebno posmatrati u kontekstu jednog od ključnih ciljeva Bolonjske deklaracije, a to je povećanje pokretljivosti radne snage. Za definisanje ishoda učenja i ključnih kompetencija, neophodno je, pored akademske zajednice, uključiti i druge zainteresovane strane. Primjena ishoda učenja se reflektuje na cijeli niz politika i praksi u opštem i strukovnom obrazovanju i osposobljavanju učenika i studenata.
Mapping the contours of humour: reflections on recent introductory studies
Authors: Condren Conal
Published: November 2021

Introductions to fields of studies are almost a sub-genre in their own right, but are often resistant to direct comparison. The essay discusses four recent introductions to humour published by university presses, and what more broadly they may signify about disciplinary advertisement and consolidation. It emphasises a range of difficulties endemic to the study of humour arising from its interdisciplinarity, recent establishment, the variable range of humour and its putative universality; in which context it pays attention to Austinian performatives, puns and their translation, and to the shared propensity in these introductions to mythologise the history of humour theory. Most critical attention is paid to the studies that form almost polar opposites: Nilsen & Nilsen, The Language of Humour and Attardo, The Linguistics of Humour.
Spontaneous humour and Malaysia’s democratic breakthrough in 2018
Authors: Shah Shanon
Published: November 2021

The 2018 Malaysian general election was the first democratic change of government in the nation’s modern history. The victory of the Pakatan Harapan (Alliance of Hope – PH) coalition surprised several observers within and outside the country, especially considering the intensified repression employed by the outgoing Barisan Nasional (National Front – BN) ruling coalition leading up to the polls, including media censorship, the silencing of political opponents, and the manipulation of Islamism and ethnic Malay nationalism. This article examines the role of spontaneous, conversational humour in constructing a viable political identity for the PH. It does this by considering humorous moments during press conferences and similar media events held by the PH coalition, led by its designated choice for prime minister, Mahathir Mohamad. This article aims to contribute to the scholarship on the role of humour in identity construction and political campaigning.
Egyptian Facebook satire: a post-Spring carnivalesque
Authors: Elsayed Yomna
Published: November 2021

The Arab Spring offered Egyptians a brief opportunity for political freedom of expression; it also offered many creative youths a chance to experiment with their newfound digital talents. However, this was soon followed by a state crackdown on public forms of dissent; subsequently, creative expression had to find other platforms and modalities to continue its practices of playful dissent. Through Mikhail Bakhtin’s (1984) theory of Carnivalesque, this paper examines how Egyptian youths managed to create alternate spaces, other than the highly scrutinised political square, to challenge officialdom and generate their own folk culture through laughter and creative digital arts. This research is based on interviews conducted with administrators and fans of Facebook pages that offer satirical content in the form of memes and remix videos. Fans of these pages mostly belong to the 1980s and 1990s generations, but they also include younger adults whose formative years were those of the Arab Spring. This study argues that, like Bakhtin’s carnival, laughter and everyday comedy was a means by which creative artists could continue to express their opinions and indirect dissent amid intensifying state surveillance. These spaces, therefore, constituted third spaces away from polarised politics, where fans could playfully discuss the comedy away from the heat of events. They were spaces where youths could exercise control over the objects of laughter and challenge established institutions. Like the carnival, youths exercised Carnival practices of both reversal and renewal to craft a new folk culture of their own that did not have to abide by the rules of patronising politics.
A fault-intrusion-tolerant system and deadline-aware algorithm for scheduling scientific workflow in the cloud
Authors: Farid Mazen , Latip Rohaya , Hussin Masnida , Abdul Hamid Nor Asilah Wati
Published: November 2021

Background

Recent technological developments have enabled the execution of more scientific solutions on cloud platforms. Cloud-based scientific workflows are subject to various risks, such as security breaches and unauthorized access to resources. By attacking side channels or virtual machines, attackers may destroy servers, causing interruption and delay or incorrect output. Although cloud-based scientific workflows are often used for vital computational-intensive tasks, their failure can come at a great cost.

Methodology

To increase workflow reliability, we propose the Fault and Intrusion-tolerant Workflow Scheduling algorithm (FITSW). The proposed workflow system uses task executors consisting of many virtual machines to carry out workflow tasks. FITSW duplicates each sub-task three times, uses an intermediate data decision-making mechanism, and then employs a deadline partitioning method to determine sub-deadlines for each sub-task. This way, dynamism is achieved in task scheduling using the resource flow. The proposed technique generates or recycles task executors, keeps the workflow clean, and improves efficiency. Experiments were conducted on WorkflowSim to evaluate the effectiveness of FITSW using metrics such as task completion rate, success rate and completion time.

Results

The results show that FITSW not only raises the success rate by about 12%, it also improves the task completion rate by 6.2% and minimizes the completion time by about 15.6% in comparison with intrusion tolerant scientific workflow ITSW system.
FORMULATION AND EVALUATION OF SUSTAINED RELEASE MATRIX TABLET OF LORNOXICAM BY DIRECT COMPRESSION METHOD
Authors: pasha Asim , Somashekhar C N
Published: November 2021

The aim of the present work was to develop sustained release Lornoxicam matrix tablets with polymers like HPMC K15M, Ethyl cellulose, and Crospovidone as carriers in varying quantities. Direct compression was used to make matrix tablets. Various assessment parameters, such as hardness, friability, thickness, percent drug content, weight variation, and so on, were applied to the prepared formulations. In vitro dissolution studies were carried out for 24 hrs. The tablets were subjected to in-vitro drug release in (pH 1.2) for first 2 hrs. Then followed by (pH 6.8) phosphate buffer for next 22 hrs. And the results showed that among the six formulations FL3 showed good dissolution profile to control the drug release respectively. The drug and polymer compatibility were tested using FT-IR spectroscopy, which revealed that the drug was compatible with all polymers. It is also required to design an appropriate prolonged release formulation for Lornoxicam in order to maintain the drug's release. Hence by using the compatible polymers sustained release tablets were formulated and subjected for various types of evaluation parameters like friability, hardness, drug content and dissolution behaviour. Finally, the findings reveal that the prepared sustained release matrix tablets of lornoxicam have improved efficacy and patient compliance.
Graduates Competence Assessment on Employability Skills: Partial Least Square-Structural Equation Modeling
Authors: Awwad Fuad A. A.
Published: November 2021

This article examines the necessary skills that students need as they graduate and enter the labor market, such as effective communication, relationship building and teamwork, leadership and management, and creative and critical thinking, among others. Some debate exists over the level at which college students develop their employability skills and the degree to which higher education institutions are effective at preparing their students to meet labor market requirements. Therefore, to offer additional insights into the debate, this study investigates the perceptions of College of Business Administration (CBA) students in the United States of their employability skills and how they developed those skills. Using a Likert-scale survey, 303 student-participants self-reported their skill levels in different employability skill competency areas. Confirmatory factor analysis was one of the structural equation modeling techniques used to explore and measure the skills that undergraduate students needed for employment. In the United States, higher education has become more expensive and students are graduating with considerable debt. Therefore, higher education institutions must be willing to address the issue of employability after graduation and find new and improved ways to develop their students’ ES, such that abilities to conceptualize that had the strongest influence on employment.
Effect of Nitrogen and Foliar Application of Naphthalene Acetic Acid (NAA) on Growth and Yield of Baby corn (Zea mays L.)
Authors: Rao Kagitha Sudharshan , Singh Shikha , Chandra K. Ravi , Dawson Joy
Published: November 2021

The experiment entitled effect of nitrogen and foliar application of naphthaleneacetic acid on growth and yield of Baby corn (Zea mays L.) was conducted during the Rabi season of 2020 at the Fodder Production Farm of Livestock Research Station, Sri Venkateswara Veterinary University, Lam Farm, Guntur. Andhra Pradesh. The experiment was laid out in Randomized Block Design with 10treatments and each replicated thrice. Treatments consisted of a combination of three levels of nitrogen (60.0, 90.0, 120.0kg/ha) and three levels of naphthalene acetic acid (20,40,60 ppm). It was found that an application of 120 kg Nitrogen/ha as basal along with foliar spray of 40 ppm naphthalene acetic acid at 25 and 35 days after sowing, was the most suitable treatment for obtaining growth and yield attributes such as plant height  (177.60 cm), number of leaves (11.33), plant dry weight (113.58g/plant), chlorophyll content (68.43), Leaf Area Index (8.65) and green fodder yield (20333 kg/ha) with net return (83,701.88 Rs/ha) and B:C ratio (1.68). On the basis of one-year experimentation it is concluded that the application of 120 kg Nitrogen/ha + 40 ppm naphthalene acetic acid, on baby corn improved cob yield by 25 % and was found more productive than the recommended dose of fertilizer.
To Assess the Common Psychosocial Problems among Women with Alcoholic Spouse
Authors: Vanlalpeka Samuel , Kasturkar Pooja , Gawai Jaya
Published: November 2021

Background: Misuse of alcohol is the most leading bewildering problem, that cast off the happiness of many families with all their possessions, which further can lead to a severe mental problem for themselves as well as their wife and their innocent children who even doesn’t face the real world. It is a fact that the wife and children, who had suffered while their fathers gave up their everything.

Objective: 1) To assess the common psychosocial problems among women with alcoholic spouses. 2) To associate common psychosocial problems score among women of the alcoholic spouse with their demographic variables.

Methodology: It is a quantitative research approach study, and it will be conducted among 100 women with an alcoholic spouse in both outpatient and inpatient psychiatric departments at Acharya Vinoba Bhava Rural Hospital, Sawangi (Meghe), Wardha. A structured knowledge questionnaire will be used to collect the data.

Expected Outcome: It is expected that there will increase mental health problems for the spouses of alcoholic patients regarding depression, anxiety, their physical and mental well-being, and their financial conditions.

Conclusions: Alcohol-related problems are not a recent problem faced by their spouse; it is a problem that remains for a long-time. This study thus will provide recent data regarding the problem faced by the spouse of an alcoholic.
Case Report on Sacroccygeal (Teratomas) Germ Cell Tumor
Authors: Nanotkar Payal , Tembhare Vaishali , Meshram Khushabu , Kasturkar Pooja , Pohekar Savita , Khandar Jaya , Gujar Samrudhi , Sawarkar Achita
Published: November 2021

Sacrococcygeal teratomas are a type of germ cell tumour (GCTs) accounting for 40% of all GCTs of all GCT,s in children. Interestingly 75% occurs in females. Reporting here a case of 3 years old female baby hospitalized for surgical excision of sacrococcygeal teratoma. A female (3-year-old) patient was referred to the pediatric outpatient department at Acharya Vinoba Bhave Rural Hospital Wardha on 19th May 2021. Complaining of swelling on right gluteal region Since 6 month and swelling is increases day by day, pain in back side, fever (Temperature - 101˚F) and tenderness in back side, leg weakness, constipation and she was admitted to Pediatric ward. Surgical excision of sacrocogygeal teratoma was done during her hospitalization. She received one cycle of chemotherapy with antineoplastic medicines. The client discharged after 10 days stay in hospital.
Association of Microbiota with Oral Potential Malignant Disorder: A Mini Review
Authors: Namburi Prasada Rao , Mahalakshmi Krishnan
Published: November 2021

Most of the oral squamous cell carcinoma (OSCC) are often preceded by oral potentially malignant disorders (OPMDs). OPMDs are defined as oral mucosal lesions and conditions which are at increased risk for undergoing alteration to oral cancer. OPMDs grow in a complex tissue microenvironment to acquire oral squamous cell carcinoma (OSCC) characteristics. Oral microbiota associated with OPMD may appear as potential biomarkers as these species may help in the diagnosis and prognosis of OPMD to OSCC. This association of microbiota to OPMD and may be helpful in the early treatment before the initiation of oral cancer. This article reviews the literature on association between microbiota and Oral potential malignant disorders.
Effectiveness of Planned Teaching on Knowledge Regarding Noonan Syndrome among Nursing Students
Authors: Alnewar Pragati , Singh Seema , Tembhare Vaishali
Published: November 2021

Background: Noonan syndrome is a genetic multisystem disorder characterized by distinctive facial features, developmental delay, learning difficulties, short stature, congenital heart disease, renal anomalies, lymphatic malformation and bleeding difficulties, mutations that cause Noonan syndrome alter genes encoding proteins with roles in the RAS-MAPK pathway, leading to pathway dysregulation. estimated prevalence of Noonan syndrome 1 in 1000-2500. Nursing student having insufficient knowledge regarding Noonan syndrome most responders perceive serious deficiencies in their preparation to care such patients As genetic advances increasingly impact nursing care, nurses are expected to have necessary knowledge to interpret genetic and genomic information and technology with translation into nursing care. The aim of the study is to aware a future nurse for Noonan syndrome, carrying the role of counsellor, care manager and teacher for patient and their families’ nurses will have an opportunity to expand as well as to create new leadership role in health care. Therefore, the development of educational program for nursing knowledge is essential for future nurses.

Objectives:

To assess the existing knowledge level regarding Noonan Syndrome among Basic B.Sc. nursing students.

To evaluate the effectiveness of planned teaching on knowledge regarding Noonan syndrome among Basic B.Sc. nursing students.

To associate posttest knowledge score with selected demographic variable.

Materials and Methods: A one group pre-test and post-test design was adopted to assess the existing knowledge level regarding Noonan Syndrome among Basic B.Sc. nursing students. In this study, evaluatory research approach will be used. convenient sampling technique will be used to collect data.  Pre-test will be conducted to assessed primarily for the existing knowledge level regarding Noonan Syndrome among Basic B.Sc. nursing students. And then planned teaching on Noonan syndrome will be given to selected sample by researcher as intervention. Post-test outcomes involve evaluation of effectiveness of planned teaching.

Expected Results: This study is planned to assess the effectiveness of planned teaching on knowledge regarding Noonan syndrome among nursing students. Conducting planned teaching will be effective for improving knowledge of the respondents.
Measurement Extraction using Fuzzy Set Rule for Segmented Features of Brain Tumor in T-1 & T-2 Weighted Images
Authors: Singh Manini , Nigam Vineeta Saxena
Published: November 2021

Aims: For neuro radiologist it becomes hard to accumulate features with minute dissimilarity in plenty of cases, so it is hard to make a correct decision. Therefore, the need is to generate some rules for prediction of degree of malignancy in tumors.

Design: The pre-operative analysis of brain lesion is based on magnetic resonance imaging and clinical data set. Analysis of MRI finding and medical data set gives the relationship between regular pattern & interpretable pattern to acquire desired degree of malignancy.  Until now the edge detection, segmentation and morphological operators are used to detect exact location of brain tumor. As uncertainty exits; here fuzzy set rules are evaluated to predict the degree by which a benign tumor is converted into malignant tumor.

Methods: Fuzzy extraction theory has been applied along with image progressing algorithms like edge detection; segmentation and morphological operation based on spectral transformation are used to detect exact location of brain tumor to predict the degree malignancy. Step of Image analysis: a) Preprocessing: input 2D gif or tiff image b) Filtering of image using Anisodiff filter c) Thresholding, applying morphological operators and tumor line detection.

Statistical Analysis used: A diagnostic feature includes blood flow, mass effect, temperature, calcification, edema, signal intensity & so on. Numerous features can be taken into consideration for better outcome.

Results: Fuzzy set rule is one of the promising methods along with MR finding to achieve accuracy higher than 85% by considering few of the medical symptoms on different features.

Conclusions: This research is limited to specific region and type of glioma and thus cannot deal heterogeneous cases in which situation is much complicated. The result evaluated here are usually retroactive. As studied, by analyzing signal intensity of T-1 & T-2 weighted image alone, accuracy of 60-70% has been achieved. So in order to get higher accuracy feature like cyst generation, oedema, blood supply are included to achieve 85% accuracy.
Development and Validation of Three Potential Genotoxic Impurities by Liquid Chromatography Single Quad Mass Detector in Iomeprol
Authors: Rao Rayala Rama , Kumar Gundapaneni Ravi , Vardhan Vadde Megha , Boddu Veeraswami
Published: November 2021

A liquid chromatography with single quadrupole mass detection method was developed for the determination of potential genotoxic impurities (PGIs) in the Iomeprol active pharmaceutical ingredient. Chromatographic separation was achieved on an Agilent Eclipse plus C8 column (100 mm x 2.1 mm x 1.8 μm) with 0.1% formic acid in water as mobile phase A and acetonitrile as mobile phase B in gradient elution mode at a 0.1 mL/min. Executed validation summary demonstrated that the mass detection method had highly sensitive and selective. A linear calibration curve (correlation coefficient, r> 0.999) was attained at the concentration range of 0.1-125 ppm for three PGI’s. The Limit of Detection of Imp-A, Imp-B and Imp-C in drug substance of Iomeprol is 0.05 ppm. The accuracy was confirmed by calculated recoveries (98.4-101.5%). The precision was tested at three levels: injection repeatability, analysis repeatability and intermediate precision. The calculated relative standard deviations were within the specification. The developed method was able to quantitate all three PGI’s at a concentration level of 1 µg/mL.
Histopathological and Histochemical Study of Human Cholecystitis
Authors: Dhamodharan V.
Published: November 2021

In our study the following inferences were made. Chronic calculous cholecystitis was seen in the age group of 41 to 50 years. A female preponderance was noted with male to female ratio of 2:3. The most common signs and symptoms were upper abdominal tenderness and right hypochondria pain. The mucosa showed ulceration in 63%, hyperplastic mucosa in 34% and metaplasia in 5%. 22% of cases showed mild (Grade-I) inflammation while 41 % of cases and 27% of cases showed moderate(Grade-2) and severe (Grade-3) inflammation respectively. 44 % of cases showed mild (Grade-I) fibrosis while 22% of cases and 15% of cases showed moderate (Grade-2) and severe (Grade-3) fibrosis. With increase 1n severity of inflammation and fibrosis, the total acid mucin content decreased while the neutral mucin content increased. Similar changes were observed in cases of metaplasia too.
Transition of Pharmaceutical Regulations: The New Regulatory Era after Brexit
Authors: Ankit Trivedi , Shrikalp Deshpande , Maitreyi Zaveri , Kumar Jain Praveen , Kiran Kolhe
Published: November 2021

Aims: The current research paper describes the regulatory changes in different pharmaceutical sectors, which are affected after the Brexit and build new guidelines that were derived from the Medicines and Healthcare Products Regulatory Agency (MHRA).

Study Design: Retrospective and concurrent review were employed to get idea regarding the regulatory changes in various pharmaceutical sectors that took place after dissimilation of Europe and Britain.

Place and Duration of Study: The present study was carried out at Amneal Pharmaceutical Ltd., from January 2021 to April 2021.

Methodology: On January 1, 2021, the MHRA had published a library of new guidance that applied as the transition period came to an end. This guidance covers the various sectors of pharmaceuticals like Clinical trials, medical devices, Importing and Exporting of pharmaceuticals, Legislation, New licensing, Pharmacovigilance and Pediatrics, which are affected due to Brexit.

Results: The MHRA laid out the future BRITAIN requirements for registering clinical trials, legal representation and importing Investigational Medicinal Products (IMPs) after the end of the Brexit, Pediatric Investigation Plan (PIP) must be included in an application for BRITAIN marketing authorization (MA). Change in Licensing procedure and the Innovative licensing and access Pathway (ILAP) provides opportunities for enhanced regulatory and other stakeholder input, including interactions with National Institute for Health and Care Excellence. Early Access to Medicines Scheme (NICE.EAMS) providing access to unlicensed, promising treatments to patients who have life threatening or rare disease indications.

Conclusion: To ensure the new approach builds on our previous success and exploits the opportunities that arise from Brexit, the industrial strategy should adopt a sophisticated supply chain view to develop an empirical base for pragmatic, joined up policies to help pharmaceutical sector grow. These policies and support will drive the BRITAIN’s pharmaceutical sector in a Post-Brexit era.
Effect of Avarai Kudineer on α- Amylase and α- Glucosidase Inhibition: A Preclinical Antidiabetic Study
Authors: Rajalakshmi K. , Shanmugapriya P. , Christian G. J. , Gladys R. Jeeva
Published: November 2021

In recent years there has been a mounting interest towards the traditional medicine globally for the treatment of type 2 diabetes. Avarai Kudineer (AK) is a Siddha classical polyherbal formulation that has been indicated for the management of Diabetes mellitus in Siddha literature. The goal of the present study is to provide an in-vitro evidence for the  antidiabetic potential of Avarai Kudineer in terms of  inhibiting the carbohydrate digesting enzymes alpha amylase and alpha glucosidase. Aavirai Kudineer (1/4) was prepared by boiling the ingredients weighed 20g in 80ml and reduced to 20ml and filtered according to the decoction preparation method as indicted in the Siddha literature. The filtrate was dissolved in DMSO to make stock solution and serially diluted to make different concentrations ranging from 10,20,40,80 and 100 µg/ml. The triplicates (n=3) were maintained. The invitro alpha amylase and alpha glucosidase enzyme inhibition of AK sample was compared with standard drug acarbose and the IC 50 value was calculated.The data was statistically analysed and expressed as Mean ± SD (n=3). The results showed that AK had maximum activity towards the inhibition of the enzyme alpha amylase (59.83± 7.10) and alpha glucosidase (71.94 ± 1.22) when compared with the standard acarbose81.42± 5.51 and 91.59 ±12.79respectively. The results reveal that the test drug AK has appreciable alpha amylase and alpha glucosidase inhibitory activity.
PENERAPAN DISIPLIN POSITIF OLEH GURU DENGAN INTEGRASI IMAN KRISTEN PADA KELAS I-A DI SEKOLAH DASAR X SURABAYA
Authors: Krisdianti Betharia , Yoedo Yuli Christiana
Published: November 2021

Murid akan menjadi penerus bangsa, maka murid perlu memiliki karakter yang baik dan benar. Karakter baik ini akan tumbuh bila guru menerapkan pembelajaran yang baik dan benar. Namun banyak guru yang masih belum menerapkan proses pembelajaran dan penerapan disiplin yang benar. Penelitian ini bertujuan untuk menjelaskan cara menerapkan disiplin kepada murid kelas I-A SD dengan menggunakan prinsip disiplin positif dan integrasi Iman Kristen pada siswa kelas I-A SD di Sekolah Dasar Kristen ‘X’ Surabaya. Melihat kasus kekerasan oleh guru dengan alasan disiplin, diharapkan penelitian ini memberi gambaran baru akan pola disiplin yang tidak menggunakan kekerasan. Penelitian ini menggunakan metode penelitian kualitatif. Guru Bahasa Inggris di kelas I-A menjadi subjek penelitian. Peneliti melakukan observasi terhitung dari bulan Agustus hingga bulan November, dan melakukan wawancara kepada subjek penelitian. Peneliti juga mengkonfirmasi data bersama wali kelas sebagai informan. Data tersebut diolah dengan menggunakan teori disiplin positif dan disiplin positif dari sudut pandang Iman Kristen dan analisis dari peneliti. Peneliti menguji apakah penerapan dapat diterima oleh murid dengan baik atau tidak, peneliti membagikan kuisioner untuk melihat respon dari murid kelas I-A. Peneliti memberi pertanyaan mengenai “apakah murid sudah mentaati peraturan yang berlaku?” sebanyak 90% menjawab sudah mentaati. 10% belum, peneliti melihat hasil observasi dan wawancara dengan subjek penelitian, melihat ada faktor dari diri murid yang membuat murid belum bisa mentaati peraturan. Perolehan data murid yang mampu mentaati perturan menunjukkan lebih dari 50%. Jadi dapat disimpulkan bahwa penerapan yang dilakukan guru Bahasa Inggris di kelas I-A ini mampu menolong murid memiliki sikap disiplin.
PERAN GURU DALAM MENINGKATKAN MOTIVASI BELAJAR MURID MELALUI PEMBERIAN ‘REWARD SUPER STUDENT’ DI SEKOLAH DASAR KRISTEN ‘B’ SURABAYA
Authors: Dewi Natalia
Published: November 2021

Dalam proses sebuah pendidikan pasti ada kalanya murid tidak mampu belajar dengan baik. Motivasi belajar membuat murid lebih mudah untuk belajar. Untuk membuat murid semangat belajar atau aktif dalam proses pembelajaran maka diperlukan guru yang memotivasi murid untuk belajar. Dalam penelitian kali ini menggunakan metode penelitian kualitatif deskriptif untuk mengetahui peran guru dalam meningkatkan motivasi belajar murid menggunakan Reward Super Student. Penelitian ini menggunakan teori behavioristic yang dicetuskan oleh B.F Skinner untuk mengetahui motivasi belajar murid. Guru memberikan Reward Super Student saat murid berhasil mencapai tujuan pembelajaran. Reward ini bisa didapatkan saat murid aktif bertanya, menjawab dan presentasi. Cara guru untuk menumbuhkan motivasi belajar murid didapatkan melalui 3 cara. Pertama, pembelajaran melalui proyek kelas. Kedua, kepemimpinan dan yang terakhir tugas tanggung jawab untuk meningkatkan motivasi belajar murid. Guru menggunakan ketiga cara tersebut untuk memotivasi belajar murid digabungkan dengan pemberian reward super student Dari hasil penelitian penggunaan Reward Super Student berhasil untuk memotivasi murid mau belajar.
HUBUNGAN PENGGUNAAN ASESMEN BERBASIS PROJECT TERHADAP KEMANDIRIAN BELAJAR MURID DI SEKOLAH DASAR TEOLOGI KRISTEN PELANGI KRISTUS SURABAYA
Authors: Sine Windy Franola
Published: November 2021

Penyelenggaraan pendidikan di Indonesia perlu membangun kemandirian murid dalam belajar. Hal ini bertujuan untuk meningkatkan kualitas pendidikan agar terciptanya sumber daya manusia yang memiliki kompetensi yang utuh. Salah satu faktor kemandirian belajar adalah asesmen berbasis project. Penelitian ini bertujuan untuk mengetahui hubungan penggunaan asesmen berbasis project terhadap kemandirian belajar murid. Jenis penelitian yang digunakan adalah penelitian korelasional berdasarkan teori Sugiyono, yang dilakukan di Sekolah dasar Teologi Kristen Pelangi Kristus Surabaya. Sampel penelitian sebanyak 45 murid dengan teknik pengumpulan data menggunakan angket kuesioner. Hasil Penelitian menunjukkan bahwa terdapat hubungan yang signifikan antara asesmen berbasis project terhadap kemandirian belajar murid.
HUBUNGAN KEHARMONISAN KELUARGA TERHADAP PERILAKU NEGATIF MURID SEKOLAH DASAR TEOLOGI KRISTEN PELANGI KRISTUS SURABAYA
Authors: Wulandari Wia
Published: November 2021

Sebanyak 153 kasus kekerasan fisik dan bullying terjadi pada tahun 2019, 39% di antaranya terjadi pada tingkat SD, di mana 30% pelakunya adalah murid sendiri. Salah satu faktor yang menyebabkan murid berperilaku negatif di sekolah adalah keharmonisan keluarga. Oleh karena itu, penelitian ini bertujuan untuk mengetahui hubungan keharmonisan keluarga terhadap perilaku negatif murid. Data diperoleh melalui pengisian kuesioner oleh 45 murid Sekolah Dasar Teologi Kristen Pelangi Kristus Surabaya yang didampingi orang tua dalam proses pengisiannya. Data dianalisis berdasarkan teori Sugiyono dengan pengujian persyaratan seperti uji normalitas dan uji linearitas data; uji regresi untuk melihat besar kontribusi variabel keharmonisan keluarga terhadap perilaku negatif murid; serta uji korelasi untuk melihat apakah ada hubungan antara keharmonisan keluarga terhadap perilaku negatif murid.
Diffusionnaya gravitatsiya i eyo sledstviya
Authors:   Centre for Theoretical Physics and Astrophysics, Zakir Zahid
Published: November 2021

Диффузионная квантовая механика (ДКМ), предложенная недавно (З. Закир, 2020-21), описывает консервативную диффузию классических частиц в флуктуирующем классическом скалярном поле и в случае однородного поля выводит формализм квантовой механики. В неоднородном скалярном поле ДКМ воспроизводит гравитацию и в данной статье рассматриваются следующая из неё теория диффузной гравитации и её различные следствия. В ДКМ часть энергии скалярного поля передаётся частицам в виде энергии их флуктуаций («тепловая» энергия), которая проявляется как их энергия покоя (масса). Результирующее локальное уменьшение плотности энергии поля вокруг макроскопического тела генерирует «тепловой» диффузионный поток частиц в эту область. Свойства этой «тепловой» части консервативной диффузии аналогичны гравитации. Высокая концентрация вещества в некоторой области снижает локальную плотность энергии скалярного поля в достаточной мере, чтобы уменьшить локальную интенсивность флуктуаций. Из-за консервативности диффузии приращения скорости дрейфа частиц являются кумулятивными, и возникает «тепловое» диффузионное ускорение, не зависящее от массы частицы. Мировые линии становятся искривлёнными, и все процессы с частицами замедляются, что означает замедление времени. На гиперповерхностях одновременности t=const, где определено скалярное поле, возникают эффективные метрики, связность и кривизна. Они подчиняются уравнениям Эйнштейна, вытекающим из баланса между энергиями материи и фонового скалярного поля.