A Multicentre, Fully Nurse-Coordinated, Intensive, Cardiovascular Prevention Intervention Programme after an Acute Coronary Syndrome
Authors:   Bachelor of Science in Nursing, Department of Health Professions - Azienda Ospedaliero-Universitaria di Parma - Department of Medicine and Surgery, University of Parma, Italy, R La Sala , G De Stefano ,   Division of Cardiology, Department of Cardio Toracic and Vascular - Azienda Ospedaliero-Universitaria di Parma, Parma, Italy, G Paoli ,   Division of Cardiology, Department of Cardio Toracic and Vascular - Azienda Ospedaliero-Universitaria di Parma, Parma, Italy, F Sinno ,   Division of General Pediatrics-Urgency, Department of Pediatrics, Azienda Ospedaliero-Universitaria di Parma - Parma, Italy, M Mattioli ,   Division of Cardiology, Department of Cardio Toracic and Vascular - Azienda Ospedaliero-Universitaria di Parma, Parma, Italy, M Ricci ,   Division of Cardiology, Department of Cardio Toracic and Vascular - Azienda Ospedaliero-Universitaria di Parma, Parma, Italy, FL Gurgoglione ,   Division of Cardiology, Department of Cardio Toracic and Vascular - Azienda Ospedaliero-Universitaria di Parma, Parma, Italy, F Barocelli ,   Division of Cardiology, Department of Cardio Toracic and Vascular - Azienda Ospedaliero-Universitaria di Parma, Parma, Italy, D Tuttolomondo ,   Division of Cardiology, Department of Cardio Toracic and Vascular - Azienda Ospedaliero-Universitaria di Parma, Parma, Italy, S Leporati ,   Division of Cardiology, Department of Cardio Toracic and Vascular - Azienda Ospedaliero-Universitaria di Parma, Parma, Italy, S Cazzato ,   Division of Cardiology, Department of Cardio Toracic and Vascular - Azienda Ospedaliero-Universitaria di Parma, Parma, Italy, D Ardissino ,   Division of Cardiology, Department of Cardio Toracic and Vascular - Azienda Ospedaliero-Universitaria di Parma, Parma, Italy
Published: March 2024

The main objective of cardiovascular disease prevention is to reduce morbidity and mortality by promoting a healthy lifestyle, reducing risk factors, and improving adherence to medications. Secondary prevention after an acute coronary syndrome has proved to be effective in reducing new cardiovascular events, but its limited use in everyday clinical practice suggests there is considerable room for improvement. The short-term results of evidence-based studies of nurse-coordinated secondary prevention programmes have been positive, but there is a lack of long-term outcome data. The Aliance for Secondary Prevention after an acute coronary syndrome in the Emilia-Romagna region (ALLEPRE) is a multicentre, randomised, controlled trial designed to compare the effects of a structured, intensive nursing intervention on long-term outcomes and risk profiles after an acute coronary syndrome with those of the standard of care. Nurses fully coordinate secondary prevention in the intervention arm using a multi- dimensional nursing form after attending ad hoc teaching sessions. All of the patients randomised to the intervention group take part in nine 1-to-1 sessions with an experienced nurse from the participating centres that have the aim of promoting healthy lifestyles, reducing risk factors, and increasing adherence to medication over a mean period of five years. The primary clinical end point is the reduction in the risk of the 5-year occurrence of major adverse events.