bluuebunny/crossref_metadata_2025 huggingface dataset:
Distribution, abundance, and health indicators of the critically endangered coral species Acropora cervicornis in Los Roques National Park, 2014
Authors: Martinez Stephanie J. , Cavada-Blanco Francoise , Cappelletto Jose , Agudo-Adriani Esteban , Aldo Croquer
Published: March 2022

Acropora cervicornis is one of the most important coral species in shallow reefs of the Caribbean as it provides habitat and structural complexity to several species of invertebrates and fish. However, the distribution range of A. cervicornis has shrunk and collapsed considerably during the last five decades, due to a combination of factors including the increase of disease prevalence, storm frequency, and anthropogenic threats. Despite being classed as “Critically Endangered” in the IUCN Red List, information regarding its population status and condition across large Caribbean coralline areas is limited. Herein we conducted the first Marine Protected Area (MPA) scale survey for this species at the Los Roques archipelago, which included visual census across 127 sites to determine the abundance, spatial distribution, habitat type (i.e., leeward, windward), and patch morphology of A. cervicornis (i.e., continuous, dispersed, scatter, isolated). We selected 11 sites, where this species was predicted and reported to be ubiquitous, to determine live A. cervicornis cover, its recent and old mortality cover, and white band disease prevalence as proxies for coral health. For this, four 25-m long photomosaics were analysed at each site. We found Acropora cervicornis in only 29% of the surveyed sites; indicating that this species currently has a narrow and very restricted distribution in Los Roques and suggesting that either this species is rare or has declined over the past decades within the MPA. Dispersed and scattered patches prevailed upon continuous patches, which only occurred in two of the surveyed sites. Moreover, these patches were located near the largest human population settlements, and inside the low protection zones of the MPA where fishing and touristic activities are permitted. The photomosaic survey showed that more than 75% A. cervicornis patches showed an average live cover above 27%, low prevalence of white band disease (<7%), and low macroalgal abundance (<10%); suggesting that Los Roques still holds healthy populations. Our results indicate that the persistence of this species urgently requires re-evaluating current MPA zoning, especially following recent evidence of overfishing and inadequate law enforcement. This study provides a baseline of A. cervicornis populations in Los Roques and Southern Caribbean that can be later used for local population management and conservation.
Methylation and Polymorphism in CDH1 Gene Promoter Among Patients with Diffuse Gastric Cancer
Authors: Vishteh Mohadeseh Naghi , Zeinalian Mehrdad , Kheirollahi Majid , Mamaghani Amirreza Javadi , Zolfaghari Mohammad Ali , Mirzapour Aliyar , Barati Meisam , Seyed Tabaei Seyed Javad
Published: March 2022

Background:

The promoter methylation and single nucleotide polymorphisms (SNPs) affect the transcription activity of cancer-related genes in several cancers including diffuse gastric cancer (DGC). Here we aimed to evaluate the promoter methylation status and the rs16260 at the promoter region of the CDH1 gene in DGC.

Methods:

This case-control study was performed of 48 formalin-fixed paraffin-embedded (FFPE) blocks of DGC patients and 41 fresh frozen tissue samples of healthy individuals. Methylation status was evaluated using methylation-specific polymerase chain reaction (PCR) and the rs16260 at the promoter region of the CDH1 gene was assessed using PCR and sequencing method.

Results:

The occurrence of methylation at the promoter region of the CDH1 gene in DGC patients was significantly higher than control samples (P < 0.0001). The methylated status was significantly associated with the poor differentiated histological type of DGC (P = 0.0428). The frequency of AC genotype and the A allele in DGC patients was significantly higher than the control subjects (P = 0.006 and 0.003, respectively).

Conclusions:

Here we showed that methylation at the CDH1 promoter may contribute to the DGC development, and also the AC genotype was associated with the risk of DGC.
Immune Responses in SARS-CoV-2, SARS-CoV, and MERS-CoV Infections
Authors: Irani Soussan
Published: March 2022

Coronavirus, discovered in the 1960s, is able to infect human hosts and causes mild to serious respiratory problems. In the last two decades, the severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been recognized. It has long been demonstrated that MERS-CoV binds to dipeptidyl peptidase 4 and SARS-CoV binds to angiotensin-converting enzyme 2. A “cytokine storm” is the main pathophysiology of aforementioned viruses. Infiltration of neutrophils at the site of the infection is a risk factor for the development of acute respiratory distress syndrome and death. The new coronavirus, SARS-CoV-2, has infected more people than SARS-Cov and MERS-CoV as it can easily be transmitted from person to person. Epidemiological studies indicate that majority of individuals are asymptomatic; therefore, an effective and an efficient tool is required for rapid testing. Identification of various cytokine and inflammatory factor expression levels can help in outcome prediction. In this study we reviewed immune responses in SARS-CoV, Mers-CoV, and SARS-COV-2 infections and the role of inflammatory cells.
Effective Programs on Suicide Prevention
Authors: Fakhari Ali , Azizi Hosein , Farahbakhsh Mostafa , Esmaeili Elham Davtalab
Published: March 2022

Background:

Health managers often do not have adequate information for decision making on what strategy makes an effective impact on suicide prevention. Despite the availability of global Suicide Prevention Programs (SPP), no previous investigation has developed combinations of a review study with expert opinions. This study was aimed to identify effective programs for suicide prevention.

Methods:

We used two methods for selecting the effective SPP. (1) review of systematic reviews: we systematically searched to find relevant review studies through Medline, Cochrane Library, PsycINFO, and gray literatures. (2) Expert panel opinions: effective programs identified from the previous step were combined with expert views via the Hanlon method.

Results:

A total of 27 since some of them were reports met the inclusion criteria. After full-text screening 9 records included. We found the following 12 SPP for prioritizing and rating the most effective interventions by an expert panel: (1) case management of Suicide Attempters (SAs), (2) identification and treatment of depression, (3) registry for suicide, (4) identifying local determinants of Suicidal behavior (SB), (5) public awareness campaigns, (6) gatekeepers’ training, (7) conducting research, (8) school-based training, (9) improving knowledge and attitudes, (10) restricting access to means, (11) at-risk people screening, (12) mass media.

Conclusions:

Seven effective SPP identified after combined 12 included interventions with expert panel opinion: (1) Case management of SAs, (2) Identification and treatment of depression, (3) Improving a registry for suicide, (4) Identifying local determinants of SB, (5) Public awareness campaigns, (6) Training gatekeepers, and (7) Conducting research.
The effect of baduanjin exercise in rehabilitation for functional ankle instability
Authors: ZHOU Li , AI Juanjuan , GENG Qingwen , LI Kuangshi , SUN Yiting , YAN Ruyu , LYU Diyang , LI Zongheng
Published: March 2022

Introduction:

Patients with functional ankle instability (FAI) have problems with joint control, balance, gait, and postural symmetry. Baduanjin is a type of traditional Chinese exercise that has been shown to be effective in treating many diseases and symptoms. However, to date, the effect of Baduanjin in patients with FAI has not been proved. This pilot trial is an assessor-blinded randomized controlled trial, and its objective is to study the efficacy and safety of Baduanjin on the rehabilitation of patients with FAI.

Methods:

Seventy-two participants, who are eligible according to specified inclusion and exclusion criteria, will be randomized (in a 1:1 ratio), using a random number table, into two groups: a Baduanjin group and a conventional treatment group. The Baduanjin group will be subjected to the Baduanjin exercise in addition to the conventional treatment therapy. Participants' exercise programs will be implemented for 4 weeks (5 days a week). All participants will be assessed at baseline, and after two and 4 weeks of treatment. The surface electromyography results of the bilateral erector spinae, tibialis anterior, and peroneus longus will be the primary outcomes, while the balance function under different conditions and the level of FAI in daily life measured using the Cumberland Ankle Instability Tool will be the secondary outcomes.

Ethics and Dissemination:

The trial has been approved by the Research Ethical Committee of Dongzhimen Hospital, the First Affiliated Hospital of Beijing University of Chinese Medicine (no. DZMEC-KY-2019-18), and it will follow the principles of the Consolidated Standards of Reporting Trials statements as well as the Declaration of Helsinki. The findings of this study will be submitted for publication in peer-reviewed journals. The results will also be disseminated to the participants via phone calls or e-mail.

Trial registration:

Chinese Clinical Trial Register ID: ChiCTR1900021939 (March 17, 2019). http://www.chictr.org.cn/.
Mediating effect of undergraduate nursing students' professional commitment on positive psychological capital and learning burnout
Authors: LI Huanze , CHEN Hongfang , ZHUANG Miaoqing , LIU Yue , WANG Jiayi , ZHANG Luyu
Published: March 2022

Objective:

The objective of this study is to explore the mediating role of professional commitment of undergraduate nursing students between positive psychological capital (PsyCap) and learning burnout.

Materials and Methods:

A cluster sampling method was used to survey 442 students of a bachelor's degree in freshman to the junior in a medical college in Shaanxi Province.

Results:

Professional commitment was positively related to positive PsyCap (= 0.487, P < 0.01), while positive PsyCap and professional commitment were negatively related to learning burnout (r = −0.456, r = −0.411, P all < 0.01). There are certain mediating effects of professional commitment in the relationship between positive PsyCap and learning burnout. The mediating effect value of professional commitment is −0.065, accounting for 16.08% of the total effect.

Conclusion:

Nursing educators in medical colleges and universities should focus on developing and training the positive PsyCap of undergraduate nursing students, thereby enhancing and stabilizing their professional commitment level and reducing the risk of learning burnout.
Analysis of risk factors for lymphedema of the lower limbs after endometrial cancer surgery and suggestions for prevention and treatment
Authors: ZHANG Qian , LIU Li-Xiu
Published: March 2022

Objective:

The objective of this study is to investigate the risk factors for the occurrence of lower limb lymphedema in patients with endometrial cancer after surgery and to make recommendations for prevention and treatment.

Materials and Methods:

We retrospectively reviewed the clinical data of 135 patients with endometrial cancer treated in the Department of Gynecology of the Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine from January 2013 to December 2019 and analyzed the risk factors of lower limb lymphedema in patients with endometrial cancer after surgery using single factor analysis and multi-factor logistic regression analysis.

Results:

The incidence of postoperative lower limb lymphedema in patients with endometrial cancer was 11.11%. The results of one-way Chi-square test analysis showed that body mass index (BMI), surgical method, number of lymph node dissection, and radiotherapy were related to the occurrence of lower limb lymphedema, and multi-factor logistic analysis showed that BMI (odds ratio [OR] = 6.207), number of lymph node dissection (OR = 4.223), and radiotherapy (OR = 8.081) were the risk factors for lower limb lymphedema after endometrial cancer surgery.

Conclusion:

Patients with endometrial cancer with BMI ≥≥25 kg/m2, high number of lymph node dissection, and postoperative radiotherapy are more likely to develop lower limb lymphedema, and they should be given priority attention and timely preventive and curative measures.
Effect of a traditional Chinese medicine theory-based mobile app on improving symptoms in patients with type 2 diabetes mellitus
Authors: XU Huiwen , YUAN Yuan , YANG Li , TAKASHI En , KITAYAMA Akio
Published: March 2022

Objective:

The aim of this study was to evaluate the effect of the Traditional Chinese Medicine (TCM) theory-based mobile app on improving symptoms in patients with type 2 diabetes mellitus (T2DM) in China.

Materials and Methods:

A randomized controlled trial was conducted. Ninety-seven patients with T2DM were enrolled and they were randomized into the control group and the experimental group. The control group was given usual diabetes education and follow-up with telephone call, while the experimental group was followed up by using the TCM theory-based mobile app. After 6-month intervention, the diabetic symptom scores, the blood glucose levels, and self-management ability of the two groups were compared.

Results:

Compared with intervention before, the levels of fasting blood glucose (FBG), 2-h postprandial blood glucose (2hPG), and glycated hemoglobin (HbA1c) decreased in the control group (9.28 ± 3.05 vs. 8.26 ± 2.73 mmol/L, 12.65 ± 4.18 vs. 10.65 ± 3.79 mmol/L, and 8.78% ±1.76% vs. 7.96% ±1.47%, respectively, all P < 0.05) and also decreased in the experimental group (8.36 ± 2.64 vs. 7.35 ± 2.45 mmol/L, 11.50 ± 4.29 vs. 9.85 ± 2.71 mmol/L, and 8.64% ±2.04% vs. 7.29% ±1.56%, respectively, all P < 0.05) after 6-month intervention, while the summary of diabetes self-care activities (SDSCAs) scale scores after 6-month intervention increased significantly in the control group (35.20 ± 14.68 vs. 44.78 ± 10.21, P < 0.05) and the experimental group (32.16 ± 13.21 vs. 50.37 ± 10.06, P < 0.05). After 6-month intervention, the diabetic symptom scores (18.16 ± 2.74 vs. 22.18 ± 4.77) and HbA1c (7.29 ± 1.56% vs. 7.96% ±1.47%) were lower, and SDSCA scale scores (50.37 ± 10.06 vs. 44.78 ± 10.21) were higher in the experimental group than the control group (all P < 0.05).

Conclusion:

The mobile app based on TCM theory can effectively improve diabetes-related symptoms in patients with T2DM and help control their blood glucose as well as enhance their self-management ability.
Comparison of in-vial exhaust method versus conventional exhaust method in the injection of COVID-19 vaccine
Authors: XU Jingjin , ZHI Hui , LI Ye , LIU Jinjing , ZHENG Wen , TANG Ling
Published: March 2022

Objective:

The objective of the study was to compare the application effects of in-vial exhaust method and conventional exhaust method in the process of coronavirus disease 2019 vaccine injection.

Materials and Methods:

Using convenient sampling method, 102 vaccines were selected as experiment group during the process of vaccine injection, and the in-vial exhaust method was used. One hundred and five vaccines were selected as the control group and the conventional exhaust method was adopted. The incidence of vaccine solution spillage and exhausting time in the two groups during exhaust were observed.

Results:

The incidence of solution spillage in the experiment group was lower than that in the control group (0 vs. 6.67%, P < 0.05). The exhausting time of the experiment group was shorter than that of the control group ([15.12 ± 4.43] s vs. [22.74 ± 6.53] s, P < 0.05).

Conclusion:

Implementing the in-vial exhaust method in the vaccine injection can effectively reduce the incidence of solution spillage, reduce nucleic acid contamination, and ensure that the vaccine is injected at the prescribed dose. Moreover, the operation is simple and easy, which improves the nurse's vaccination efficiency, and has a higher promotion and application value.
A study on the correlation between function motivation and professional identity among nursing volunteers
Authors: XU Juan , HAO Wenjun , YANG Hui , LI Xuanxuan
Published: March 2022

Objective:

The objective of this study is to understand the status quo of function motivation and professional identity among nursing volunteers and explore the correlation between the two.

Materials and Methods:

A total of 3375 nursing volunteers from Nightingale Volunteer Service Group in Shanxi Province were investigated by using Occupational Identity Scale and Volunteer Functional Motivation Scale.

Results:

A total of 3375 questionnaires were issued and 3330 were recovered, among which 3324 were valid, with an effective recovery rate of 99.82% (3324/3330). The overall score of professional identity of nurses was 110.31 ± 18.71, and the score of each dimension was 32.17 ± 6.62 for professional cognitive evaluation dimension, 22.77 ± 3.74 for professional social support, 21.31 ± 4.09 for professional social skills, 22.78 ± 3.79 for professional frustration coping, and 11.32 ± 2.03 for professional self-reflection. The total score of function motivation was 157.12 ± 29.92. The above five dimensions of nurse's professional identity scale were positively correlated with the total score of function motivation of nursing volunteers (r = 0.044, 0.035, 0.034, 0.035, and 0.042, respectively, all P < 0.05).

Conclusion:

The functional motivation and professional identity of nursing volunteers in Shanxi Province are in the middle level in China. Therefore, it is necessary for the hospital to stimulate nursing staff's enthusiasm about participation by carrying out multi-channel and multi-form volunteer service projects, enhance their professional identity, and make them better give back nursing professional skills to the society.
Self-management of cataract extraction among diabetes patients
Authors: AKINTUNDE Funke Elizabeth , OLORUNFEMI Olaolorunpo , SALAWU Rasidi Akinade , OYEKANMI Mary Olabisi , ADEYENI Babatunde Abdul-latef , OLADAPO Olawale Rasheed , SODIMU Jeminat Omotade
Published: March 2022

Background:

Diabetes-related cataract extraction is a minor surgery required to regain full vision. One of the recognized factors that can delay or prevent full-vision recovery is poor management, and most of this management is being carried out by patients themselves.

Objective:

This study aimed to assess the knowledge of diabetes patients on self-management after cataract extraction in two tertiary hospitals in Osun State.

Methods:

A cross-sectional descriptive design was conducted among 97 diabetes patients who underwent cataract extraction and were attending clinics and follow-up visits in Osun State. A self-structured questionnaire was used for data collection.

Results:

Moderate knowledge was found among the participants on an appropriate diet (56.7%), prevention of injury risk (57.5%), prevention of infection risk (50.9%), and low knowledge on the technique of administration of eye drop (60.8%) after cataract extraction, whereas 74.7% of the total respondents were knowledgeable on the indication for follow-up visit after cataract extraction, these results were found to be below the expected knowledge level.

Conclusion:

An intensive and comprehensive educational initiative by nurses should be tailored to meet the specific needs of diabetes patients with cataract surgery. Nurses also need to implement the use of checklist which will enhance learning and improve patient understanding of self-management after cataract extraction.
Knowledge on malaria among caregivers with children aged under 5 years at Kenyasi Health Center
Authors: ANSONG Cecilia Ackon , AGYEI Frank Bediako , AGAMBIRE Ramatu , BAYUO Jonathan
Published: March 2022

Background:

Malaria remains one of the leading causes of morbidity and mortality among children under 5 years old in many low- and middle-income countries. According to the Ghana National Malaria Control Program, malaria kills at least three children every day and also tops the outpatient department cases in Ghana.

Objective:

The present study sought to determine the knowledge of malaria among caregivers of children under 5 years at Kenyasi Health Center, Ghana.

Materials and Methods:

The study was a descriptive, cross-sectional study. One hundred and three caregivers with children under 5 years old were recruited using the systematic random sampling technique, and data were collected using a structured questionnaire.

Results:

The findings revealed that majority (98%) of the respondents knew at least one cause of malaria. Furthermore, all respondents knew at least one complication of malaria and majority (97%) knew at least one preventive measure of malaria.

Conclusion:

Caregivers of children have adequate knowledge about malaria and its mode of transmission. Further education on the implementation of the preventive methods is still needed to help reduce the incidence of malaria among children.
Relationship of demoralization with anxiety, depression, and demographics of Chinese dialysis patients
Authors: ZHUANG Cai-Lan , ZHENG Juan-Lian , GAO Lei , HUANG Ying-Ling , HU Wen-Jing
Published: March 2022

Objective:

The purpose of this study is to investigate the demoralization level of dialysis patients in China and analyze the influencing factors.

Materials and Methods:

A convenience sample of 278 dialysis patients from a tertiary hospital participated in a cross-sectional descriptive study using a structured questionnaire including assessments of demographic data, Demoralization Scale-II (DS-II), and Hospital Anxiety and Depression Scale. The main analysis consisted of descriptive statistics, correlation coefficients, and multiple linear regression.

Results:

The mean standard deviation DS-II score was 11.87 (7.72). Dialysis patients had a high level of demoralization. Findings from multiple linear regression indicated that demoralization was positively correlated with marital status (β = 0.141; P = 0.001), employment status (β = 0.113; P = 0.006), anxiety (β = 0.393; P < 0.001), and depression (β = 0.224; P < 0.001). These variables explained 57.1% of the variance in patient demoralization.

Conclusions:

Demoralization is common in dialysis patients and is associated with marital status, employment status, anxiety, and depression. Health-care providers might regularly assess demoralization in dialysis patients, and develop related interventions to improve the quality of life.
Moxibustion plus acupuncture improves the efficacy and quality of life of patients with polycystic ovary syndrome
Authors: ZHANG Qian , LIU Li-xiu
Published: March 2022

Objective:

To observe the effect of moxibustion combined with acupuncture on the efficacy and quality of life of spleen-kidney-yang-deficiency patients with polycystic ovary syndrome (PCOS).

Materials and Methods:

A total of 90 patients with PCOS of spleen-kidney yang deficiency type from January 2020 to March 2021 were selected and randomly divided into three groups, 30 patients each in the moxibustion group, acupuncture group, and moxibustion combined with acupuncture group (combined group). The changes of body mass index (BMI), waist-to-hip ratio (WHR), fasting insulin (FINS), fasting plasma glucose (FPG), homeostasis model assessment-insulin resistance index (HOMA-IR), follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T), triglycerides (TG), total cholesterol (TC), traditional Chinese medicine (TCM) clinical symptom score, efficacy, and quality of life score in the three groups were observed before and 3 months after treatment.

Results:

After treatment, (1) compared with the moxibustion and acupuncture groups, the combined group was more effective in reducing BMI (F = 5.274, P < 0.05) and WHR (F = 8.246, P < 0.05) in PCOS patients; (2) FINS, FPG, and HOMA-IR were reduced in all three groups, and the reduction in these three indicators was more pronounced in combined group (FINS: F = 5.637, P < 0.05, FPG: F = 4.915, P < 0.05, HOMA-IR: F = 3.817, P < 0.05); (3) The FSH, LH, and T levels of patients in the combined group were better than those in the remaining two groups (FSH: F = 4,163, P < 0.05, LH: F = 5.098, P < 0.05, T: F = 7.038, P < 0.05); (4) The TG and TC of patients in the combined group were lower than those in the remaining two groups (TG: F = 4.806, P < 0.05, TC: F = 3.828, P < 0.05); (5) The TCM clinical symptom score of the combined group was significantly lower than those of the moxibustion and acupuncture groups (F = 4.547, P < 0.05); (6) The quality of life of patients in the combined group improved more significantly than the moxibustion and acupuncture groups (F = 6.239, P < 0.05); (7) The total effective rate of the combined group was higher than that of the moxibustion and acupuncture groups (χ
2 = 6.947, P = 0.031).

Conclusion:

The combination of moxibustion and acupuncture can effectively reduce the BMI and WHR of PCOS patients, improve the endocrine function, sex hormone level, TCM symptoms and quality of life of patients, and has significant efficacy and high safety, which is worthy of wide clinical application.
Application of rehabilitation nursing technology in the pulmonary rehabilitation of the patients after lung cancer operation
Authors: XU Yuzhen , HAN Lin
Published: March 2022

The rehabilitation nursing of lung function at home for lung cancer patients after operation can not only improve the level of lung function and the quality of life but also improve the compliance of patients with treatment and improve their psychological status. Studies have shown that respiratory training, exercise training and rehabilitation nursing techniques of Chinese medicine, such as Six-Word Qigong, Tai Chi and Baduanjin have better effects on lung function recovery in patients after lung cancer surgery. In this paper, we made review and discussion on the application of the above methods in patients with lung cancer at home after operation.
Scientific publications in nursing journals from East Asia
Authors: LIU Zhi-Chen , PU Ya-Lou , WANG Yong-Hua , GAO Li , WANG Jing , CAO Bao-Hua
Published: March 2022

Background:

East Asia is one of the most important economy and research force in the world. However, the trend of published articles in various areas of East Asia has not been reported.

Methods:

We used PubMed and Web of Science databases to search for articles published from China, South Korea, and Japan in 59 nursing journals, from January 2008 to December 2017.

Results:

The results indicated that Journal of Clinical Nursing is the most popular journal in East Asia and the number of articles published in China has shown a steady upward trend, surpassing Japan and South Korea (from 204 in 2008 to 320 in 2017). South Korea has increased rapidly since 2013 (from 65 in 2013 to 144 in 2017).

Conclusion:

We conclude that China is the most influenced country with the largest number of articles in the field of nursing in East Asia. It is worth noting that the number of articles published in Japan has been slowly declining since 2015.
Correlation between psychological factors and the expression of galanin and 5.hydroxytryptamine in different subtypes of gastroesophageal reflux disease
Authors: YUAN Yuan , XU Hui-Wen , ZHANG Song , TAKASHI En , AKIO Kitayama , LIANG Jing-Yan
Published: March 2022

Objective:

The aim of this study is to analyze the differences in galanin (GAL) and 5-hydroxytryptamine (5-HT) levels in patients with different subtypes of gastroesophageal reflux disease (GERD) and its correlation with anxiety and depression in patients.

Methods:

Using the reflux disease questionnaire, 238 patients with GERD were selected as the study group. According to the endoscopic performance, they were divided into the nonerosive reflux disease (NERD) group (114 patients) and the RE group (124 patients). Sixty healthy people were selected as the control group. All research subjects were tested using the self-rating anxiety scale (SAS) and the self-rating depression scale (SDS) to assess the severity of anxiety and depression. The levels of 5-HT and GAL were analyzed using enzyme-linked immunosorbent assay.

Results:

Compared with the control group, 5-HT level in GERD patients without anxiety and depression was higher (t = 1.97, P < 0.05) and GAL level was lower (t = 1.97, P < 0.05). NERD patients demonstrated more server anxiety (F = 55.92, P < 0.05) and depression problems (F = 36.51, P < 0.05) compared to reflux esophagitis (RE) patients. The 5-HT level was lower (F = 54.53, P < 0.05) and the GAL level was higher (F = 8.00, P < 0.05) in NERD patients compared with the control group. Furthermore, 5-HT level was negatively correlated with SAS (r = −0.789, P < 0.05) and SDS (r = −0.787, P < 0.05) scores; GAL level was positively correlated with SAS (r = 0.688, P < 0.05) and SDS (r = 0.705, P < 0.05) scores; 5-HT and GAL level were negatively correlated (r= −0.744, P < 0.05).

Conclusions:

5-HT level is higher and GAL level was lower in GERD patients without anxiety and depression than healthy people; the symptoms of anxiety and depression of NERD patients are more severe compared to those of RE patients; the severity of anxiety and depression was negatively correlated with the level of 5-HT and positively with GAL level.
Application of empowerment education in health education for cancer patients
Authors: PENG Yan , HAN Lin , AN Fang-Fang , LI Li , HOU Yue-Li
Published: March 2022

Empowerment education aims to stimulate the intrinsic motivation of patients and make them pay more attention to their own health so as to control the disease. This paper expounds the concept, theoretical framework, implementer, object, implementation steps, forms, and evaluation methods of empowerment education for cancer patients, in order to provide practical guidance for clinical workers.
The impacts of resilience on the association between illness uncertainty and sleep quality among patients with type 2 diabetes mellitus
Authors: WANG Xin-Ge , WEN Yu-Qiong , KUANG Hui-Bing , LIN Li-Xia , CUI Hong
Published: March 2022

Objective:

The objective was to investigate the relationship between resilience, illness uncertainty, and sleep quality in patients with type 2 diabetes mellitus (T2DM).

Methods:

This cross-sectional study was conducted from September 2019 to August 2020 from a tertiary hospital in Guangzhou, China. Totally, 205 participants completed questionnaires concerning demographic characteristics, Pittsburgh sleep quality index, Mishel uncertainty in illness scale (MUIS), and Connor–Davidson Resilience Scale (CD-RISR) were collected by convenience sampling. Multiple hierarchical regression analysis was used to evaluate the interaction of illness uncertainty, resilience, and sleep quality. The mediating role of resilience was also tested.

Results:

The total score of illness uncertainty was 94.68 ± 11.19 in T2DM patients, which was proved in the medium level. There was a significant negative correlation between the total CD-RISR score and total MUIS score (r = −0.716, P < 0.01); there was a significant negative correlation between the total CD-RISR score and total PISQ score (r = −0.806, P < 0.01); total MUIS score was positively correlated with PISQ score (r = 0.872, P < 0.01). Psychological resilience could partially mediate the association between sleep quality and the level of illness uncertainty, and the mediating effect was 0.293, accounting for 34.20% of the total effect.

Conclusion:

Patients with T2DM have a moderate level of illness uncertainty, and it was negatively correlated with mental resilience level and positively associated with sleep quality. Medical staff should strengthen psychological intervention for T2DM patients to reduce the sense of uncertainty.
Evidence summaries for nutritional screening of head-and-neck cancer patients
Authors: LI Ye , LIU Yi-Yuan , TIAN Ya-Juan , TANG Ling
Published: March 2022

The guidelines for nutritional screening of head-and-neck cancer patients were systematically searched and screened from BMJ Best Practice, National Comprehensive Cancer Network, Britain's National Institute for Health and Clinical Excellence, National Guideline Clearinghouse, Scottish Intercollegiate Guidelines Network, Guidelines International Network, New Zealand Guidelines Group, Australian National Health and Medical Research Council, Medlive, PubMed, Embase, CINAHL, China Biology Medicine, VIP, Chinese National Knowledge Infrastructure, and Wanfang. Four researchers evaluated the quality of the included literature and extracted evidence from the literature that met the quality standards. Finally, a total of six guidelines were included and ten best evidences were concluded. As only one guideline in this study is from China, and the rest are from other countries, the applicability and effectiveness of some evidence in the Chinese population still need to be further explored and studied. Therefore, when using evidence, medical staff should make appraisal on working environment in their hospital, factors that facilitate or hinder the use of evidence, and willingness of patients, and thus scientifically provide the best evidence for the management of clinical nutrition for head-and-neck cancer patients and provide a reference for the establishment of the standard process of nutritional screening for head-and-neck cancer patients.
Graphs containing finite induced paths of unbounded length
Authors: Pouzet Maurice , Zaguia Imed
Published: March 2022

The age $\mathcal{A}(G)$ of a graph $G$ (undirected and without loops) is the
collection of finite induced subgraphs of $G$, considered up to isomorphy and
ordered by embeddability. It is well-quasi-ordered (wqo) for this order if it
contains no infinite antichain. A graph is \emph{path-minimal} if it contains
finite induced paths of unbounded length and every induced subgraph $G'$ with
this property embeds $G$. We construct $2^{\aleph_0}$ path-minimal graphs whose
ages are pairwise incomparable with set inclusion and which are wqo. Our
construction is based on uniformly recurrent sequences and lexicographical sums
of labelled graphs.
Efficient recurrence for the enumeration of permutations with fixed pinnacle set
Authors: Fang Wenjie
Published: March 2022

Initiated by Davis, Nelson, Petersen and Tenner (2018), the enumerative study
of pinnacle sets of permutations has attracted a fair amount of attention
recently. In this article, we provide a recurrence that can be used to compute
efficiently the number $|\mathfrak{S}_n(P)|$ of permutations of size $n$ with a
given pinnacle set $P$, with arithmetic complexity $O(k^4 + k\log n)$ for $P$
of size $k$. A symbolic expression can also be computed in this way for
pinnacle sets of fixed size. A weighted sum $q_n(P)$ of $|\mathfrak{S}_n(P)|$
proposed in Davis, Nelson, Petersen and Tenner (2018) seems to have a simple
form, and a conjectural form is given recently by Flaque, Novelli and Thibon
(2021+). We settle the problem by providing and proving an alternative form of
$q_n(P)$, which has a strong combinatorial flavor. We also study admissible
orderings of a given pinnacle set, first considered by Rusu (2020) and
characterized by Rusu and Tenner (2021), and we give an efficient algorithm for
their counting.
$G$-fixed Hilbert schemes on $K3$ surfaces, modular forms, and eta products
Authors: Bryan Jim , Gyenge Ádám
Published: March 2022

Let $X$ be a complex $K3$ surface with an effective action of a group $G$ which preserves the holomorphic symplectic form. Let $$ Z_{X,G}(q) = \sum_{n=0}^{\infty} e\left(\operatorname{Hilb}^{n}(X)^{G} \right)\, q^{n-1} $$ be the generating function for the Euler characteristics of the Hilbert schemes of $G$-invariant length $n$ subschemes. We show that its reciprocal, $Z_{X,G}(q)^{-1}$ is the Fourier expansion of a modular cusp form of weight $\frac{1}{2} e(X/G)$ for the congruence subgroup $\Gamma_{0}(|G|)$. We give an explicit formula for $Z_{X,G}$ in terms of the Dedekind eta function for all 82 possible $(X,G)$. The key intermediate result we prove is of independent interest: it establishes an eta product identity for a certain shifted theta function of the root lattice of a simply laced root system. We extend our results to various refinements of the Euler characteristic, namely the Elliptic genus, the Chi-$y$ genus, and the motivic class.

Comment: Published version. Greatly simplified proof of Proposition 3.1
Analysis of Activity Dependent Development of Topographic Maps in Neural Field Theory with Short Time Scale Dependent Plasticity
Authors: Gale Nicholas , Rodger Jennifer , Small Michael , Eglen Stephen
Published: March 2022

Topographic maps are a brain structure connecting pre-synpatic and
post-synaptic brain regions. Topographic development is dependent on
Hebbian-based plasticity mechanisms working in conjunction with spontaneous
patterns of neural activity generated in the pre-synaptic regions. Studies
performed in mouse have shown that these spontaneous patterns can exhibit
complex spatial-temporal structures which existing models cannot incorporate.
Neural field theories are appropriate modelling paradigms for topographic
systems due to the dense nature of the connections between regions and can be
augmented with a plasticity rule general enough to capture complex time-varying
structures.
We propose a theoretical framework for studying the development of topography
in the context of complex spatial-temporal activity fed-forward from the
pre-synaptic to post-synaptic regions. Analysis of the model leads to an
analytic solution corroborating the conclusion that activity can drive the
refinement of topographic projections. The analysis also suggests that
biological noise is used in the development of topography to stabilise the
dynamics. MCMC simulations are used to analyse and understand the differences
in topographic refinement between wild-type and the $\beta2$ knock-out mutant
in mice. The time scale of the synaptic plasticity window is estimated as
$0.56$ seconds in this context with a model fit of $R^2 = 0.81$.
3-D Modelling of Fractal Nanoclusters Using the Iterated Affine Transformations Systems Method
Authors: Avilov S.V. , Zhukalin D.A. , Bityutskaya L.A. , Domashevskaya E.P.
Published: March 2022

In the current work an approach for fractal nanocluster 3-D modelling is proposed using the iterated affine transformations system method. The symmetry of regular polyhedra concept is applied. It is shown that the models can be used to interpret experimental results.
Mathematical Modeling of the Evolution of the Exterior Boundary in Spheroidal Tumour Growth
Authors: Kariotou Foteini , Vafeas Panayiotis , Papadopoulos Polycarpos K.
Published: March 2022

The present paper concerns the formulation and the evolution of the non symmetrical growth of an avascular cancerous cell colony in an analytical mathematical fashion. Although most of the existing research considers spherical tumours, here we work in the frame of a more general case of the prolate spheroidal geometry. The tumour lies inside a host spheroidal shell which provides vital nutrients, receives the debris of the dead cells and also transmittes to the tumour the pressure imposed by the surrounding on its exterior boundary. Under the aim of studying the evolution of the exterior tumour boundary, we focus on the exterior conditions under which such a geometrical structure can be sustained. To that purpose, the corresponding nutrient concentration, the inhibitor concentration and the pressure field are calculated analytically providing the necessary data for the evolution equation to be solvable. It turns out that an avascular tumour can exhibit a prolate spheroidal growth only if the external conditions for the nutrient supply and the transversally isotropic pressure field have a specific form, which is consistent with the tumour evolution. Additionally, our model exhibits a geometrical reduction to special cases and, mainly, to the spherical geometry in order to recover the existing results for the sphere.
A Wave Diffraction Problem with Higher Order Impedance Boundary Conditions
Authors: Simoes A. M.
Published: March 2022

In this paper, we consider an impedance boundary transmission problem for the Helmholtz equation originated by a problem of wave diffraction by an infinite strip with higher order imperfect boundary conditions. Operator theoretical methods and relations between operators are built to deal with the problem and, as consequence, a transparent interpretation of the problem in an operator theory framework are associated to the problem. In particular, different types of operator relations are exhibited for different types of operators acting between Lebesgue and Sobolev spaces on a finite interval and the positive half-line. All this has consequences in the understanding of the structure of this type of problems. At the end, we describe when the operators associated with the problem enjoy the Fredholm property in terms of the initial space order parameters.
Subordination Formulae for Space-time Fractional Diffusion Processes via Mellin Convolution
Authors: Pagnini Gianni
Published: March 2022

Fundamental solutions of space-time fractional diffusion equations can be interpret as probability density functions. This fact creates a strong link with stochastic processes. Recasting probability density functions in terms of subordination laws has emerged to be important to built up stochastic processes. In particular, for diffusion processes, subordination can be understood as a diffusive process in space, which is called parent process, that depends on a parameter which is also random and depends on time, which is called directing process. Stochastic processes related to fractional diffusion are self-similar processes. The integral representation of the resulting probability density function for self-similar stochastic processes can be related to the convolution integral within the Mellin transform theory. Here, subordination formulae for space-time fractional diffusion are provided. In particular, a noteworthy new formula is derived in the diffusive symmetric case that is spatially driven by the Gaussian density. Future developments of the research on the basis of this new subordination law are discussed.
Humbert Polynomials and Functions in Terms of Hemite Polynomials
Authors: Cesarano C. , Assante Dario
Published: March 2022

By starting from the standard definitions of the incomplete two-variable Hermite polynomials, we propose non-trivial generalizations and we show some applications to the Bessel-type functions as the Humbert functions. We also present a generalization of the Laguerre polynomials in the same context of the incomplete-type and we use these to obtain relevant operational techniques for the Humbert-type functions.
Some Advantages of the Hybrid Methods, Which Used the First Derivative of the Solution of the Considered Problem
Authors: Mehdiyeva G. , Imanova M. , Ibrahimov V.
Published: March 2022

The scientists began investigate of the solution of ODE from the XVII century. Many famous mathematicians as Newton, Leibniz, Bernoulli, D’ Alembert, Euler, Cauchy and etc. have considered solving of the ordinary differential equations. For solving these equations the scientists from the different country have constructed many methods. Here, with the help of the compare known results are shown some advantages of the hybrid methods. Are constructed the hybrid methods with the order of accuracy p = 8k . Here, is suggested concrete hybrid method of the fractional step type with the order of accuracy p = 8 for k =1 for which uses the first order derivative of the solution of the initial value problem.
Operational Methods for Hermite Polynomials
Authors: Cesarano C.
Published: March 2022

We exploit methods of operational nature to derive a set of new identities involving families of polynomials associated with operators providing different realizations of the Weyl group. The identities, we will deal with, extend the Nielsen formulae, valid for ordinary Hermite to families of Hermite-like polynomials. It will also be shown that the underlying formalism yields the possibility of obtaining further identities relevant to multi-variable and multi-index polynomials.
Some Results via De La Vallée-poussin Mean in Probabilistic 2-normed Spaces
Authors: Yamancı U. , Gürdal M. , Aytar S.
Published: March 2022

In this article we introduce some new type of summability methods for double sequences involving the ideas of de la Vallée-Poussin mean in probabilistic 2 -normed space and examine some important results.
Elliptic Curves Over The Quadratic Field
Authors: Abdelalim S. , Chillali A. , Elhajji S.
Published: March 2022

In this paper, we introduce some fundamental results of the elliptic curve over the quadratic field. After we create an elliptic curve over the quadratic field with an element of infinite order.[2,3,4].
Differentiation Functors and Category Interpretation of Optimality Conditions
Authors: Serovajsky S. Y. , Diarova D. M.
Published: March 2022

Operator derivatives are determined as functors. Necessary optimality conditions with category interpretation are proved for abstract optimization control problems. Finite dimensional extremum problems and an optimization control problem for nonlinear parabolic equation with state constraints are considered as examples.
Lp and BMO-solvability of the Dirichlet Problem for Elliptic Operators
Authors: Zecca Gabriella
Published: March 2022

We establish a connection between the solvability of end-point BMO and Lp Dirichlet problems for a second order divergence form elliptic operator (not necessarily symmetric) with bounded measurable coefficients. In particular, we give a lower bound for the exponent p > 1 in terms of the BMO-constant of L (see Definition 8).
SOKAK HAYVANLARI İÇİN NESNELERİN İNTERNETİ TABANLI AKILLI BESLEME MAKİNASI
Authors: MERAL Metehan , SARITAŞ Ahmet Arif , MERAL Aziz , GENÇ Abdullah
Published: March 2022

Günümüzde sokaklarda yaşayan hayvanlar, özellikle kış aylarında yiyecek sıkıntısıyla karşı karşıya kalmaktadır. Özellikle küresel pandemi sebebiyle alınan önlemler, sokak hayvanlarını daha mağdur bir duruma düşürmüştür. Çeşitli destek kampanyalarıyla geçici çözümler sağlansa bile kalıcı ve sürdürülebilir yollarla onların beslenmesi önemli bir konudur. Bu çalışmada, bu problemin bir kısmının ortadan kaldırılması amacıyla akıllı besleme makinasının prototip tasarım ve üretimi gerçekleştirilmiştir. Bu sayede, internet ortamından günün herhangi bir saatinde istenilen bölgedeki (park, millet bahçesi vb.) akıllı mama makinasına bağlanarak belirtilen miktarda mama bağışı sağlanabilecektir. Bunun için ilk olarak bağış yapılabilmesini sağlamak için bir internet sitesi tasarlanmıştır. Daha sonra wi-fi tabanlı mikro denetleyici kart kullanılan elektronik sistem için ayrıca PCB tasarımı gerçekleştirilmiştir. Site vasıtasıyla bağış yapıldıktan sonra cihaza görsel erişim sağlanması için kamera modülü kullanılmıştır. Elektronik ünitenin bulunacağı katı model ise Solidworks ortamında tasarlanmıştır ve 3B baskıyla imal edilmiştir.
Trabalhadores da educação: re-construção de caminhos no mundo do trabalho
Authors: Peres Sonia Maria Zanezi
Published: March 2022

Esse artigo caracteriza os fundamentos da relação entre trabalho e educação. Nos apresenta como não obstante a indissolubilidade da referida relação que se manifestou na história o fenômeno da separação entre trabalho e educação. Abordamos o processo de restabelecimento dos vínculos entre trabalho e educação que vem marcando a sociedade moderna. Finalmente, esboça a conformação dos trabalhadores da educação sob a égide do trabalho como princípio educativo.