bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparing Adjuvant Beta Radiation, Mitomycin C, and Conjunctival Autograft in Primary Pterygium Treatment, a Three-year Follow-up Study
Authors: Al-Salem Khalil M. , Saif Ahmad T.S. , Saif Passant S.
Published: January 2021

Purpose:

To compare the recurrence rate of primary pterygium surgery after the adjuvant use of Beta radiation, Mitomycin C, and conjunctival autograft.

Methods:

180 eyes of 180 patients were included in the study. All cases had primary pterygium excision following the use of adjuvant therapy of Beta radiation or Mitomycin C (0.02% for 5 minutes) or conjunctival autograft. The study was conducted at Fayoum University Hospital, Fayoum, Egypt, and Misr University Hospital. The patients were randomly divided into three groups, with each group comprising 60 patients. Group (A) included patients treated with Beta radiation following Pterygium excision, group (B) patients had primary pterygium excision with the application of 0.02% Mitomycin C for 5 minutes, and group (C) patients had conjunctival autograft to cover the bare area after pterygium excision. Patients were followed up for three years postoperatively.

Results:

group A had the highest recurrence rate (33.3%) followed by group B (13.3%), and finally group C presented a recurrence rate of 6.7%. Group B showed the highest rate of intra-ocular postoperative complications, while no intra-ocular complications were recorded in group C. Common complications in groups A and B were scleral melting, keratitis, and Dellen formation.

Conclusion:

Using conjunctival autograft after primary pterygium excision gives the best results regarding the rate of recurrence and postoperative complications. Meanwhile, B-radiation or Mitomycin C did not prove to be as good.
Sole Anti-inflammatory Immunomodulators: Innovative Drugs to Prevent and Treat Autoimmune Diseases and Proteopathies
Authors: Marciani Dante J.
Published: January 2021

Objective:

To review the available sole anti-inflammatory immunomodulators or adjuvants,
different from pro-inflammatory ones, which elicit a Th2 immunity while inhibiting but
without abrogating Th1/Th17 immunities. Adjuvants that are useful to develop vaccines for T-cell
mediated autoimmune conditions.

Methods:

A literature search using PubMed and Google Scholar databases was made to identify
reports regarding adjuvants, mechanisms of action, pro-inflammatory autoimmunity and vaccines
to treat it, immunosuppressive agents, dendritic cells, helminths, immunotolerance, and infectious
diseases causing autoimmunity.

Results:

Some anti-inflammatory drugs to treat autoimmune diseases inhibit DNA or protein synthesis
causing global immunosuppression, which is reduced by using biologics to block key steps
in the inflammatory cascade. Fucosylated glycans from helminths, which are anti-inflammatory
but not immune-suppressive, offer an avenue to develop better drugs. Fucosylated glycans bind to
DC-SIGN, a receptor on dendritic cells, entering the cells via receptor-mediated endocytosis, biasing
their immunoresponse to a sole Th2 anti-inflammatory immunity, while inhibiting the proinflammatory
Th1/Th17 immunities. New anti-inflammatory drugs are particular plant-derived
fucosylated glycosides with immunological properties like those of helminth-derived glycans.
Another class of anti-inflammatory immunomodulators is ligands of the aromatic-hydrocarbon
receptor, which by activating this intracellular receptor, boosts the differentiation of regulatory Tcells,
inducing an anti-inflammatory immunity. However, aromatic ligands can also stimulate a
pro-inflammatory response. Exogenous aromatic ligands are usually delivered intracellularly using
carriers like nanoparticles, which upon translocation to the nucleus, activate this receptor.

Conclusions:

Autoimmune conditions and some infectious diseases, characterized by organ damage
due to pro-inflammatory autoimmune immunoresponses, could benefit from nonimmunosuppressive
agents to modulate immunity; this way, averting a damaging inflammation.
A Statistical Quality Control (SQC) Methodology for Gold Nanoparticles Based Immune-chromatographic Rapid Test Kits Validation
Authors: Manta Prince , Wahi Nitin , Bharadwaj Alok , Kour Gurmeet , Kapoor Deepak N.
Published: January 2021

In the current virus infection and pandemic situation, the extremely convenient gold nanoparticles
sensor (AuNPs) dependent antibody and antigen detection kits are very important assays for infection
detection. Various laboratories and manufacturers across the globe are utilizing different kits development
and manufacturing processes, but the development of kits and large scale manufacturing are
two different things. A manufacturing process needs to be controlled for financial, quality and regulatory
compliance. The best way to control the process is by statistical method. The process produces products
that contain variables as critical quality attributes (dependent variables) are predicted over the
processing time. There are distinct immune-chromatographic point to care diagnosis devices and kits
available with different quality attributes like antigen-antibody proteins, aptamers, markers (nanoparticles,
latex beads, and fluorescence) and devices performance attributes, etc. Such attributes add uncertainty
to the durability of such instruments. The gold nanoparticles are one of the key attributes, which
certainly defines the performance of kits (sensitivity, specificity and uniformity). To establishing the
manufacturing process capability, the static tolerance intervals are critical for the synthesis of gold nanoparticles,
protein conjugation, and nitrocellulose membrane coating. In the immune test kits, critical
process parameters (independent variable) affect dependent responses can be controlled statistically by
fitting purpose methodology. The manufacturing process is to be established in the state of engineering
control by setting up the critical process parameters. Statistically, the manufacturers can predict and
handle out-of-specification (OOS) results even if the process is inconsistent and unstable. This article
provides scientific tools to the reader to determine whether or not a gold nanoparticles based immunechromatographic
development process is statically capable of scale-up.
Short, but Highly Concentrated, Direct Inhalations of Essential Oil Molecules Improve Poor Sleep Quality: A Natural History Controlled, Withingroup, Self-administration Field Pilot Study
Authors: Schneider Rainer
Published: January 2021

Background:

Essential oils are among the preferred alternative remedies for treating sleep disturbance, but empirical evidence for their effectiveness is varied. According to a new line of research, an inhaler designed to deliver high concentrations of essential oil molecules directly into the nose effectively influences the hypothalamic-pituitaryadrenal axis and the autonomous nervous system.

Objective:

This study was run to investigate whether insomnia complaints were reduced upon use of the inhaler AromaStick® ‘Relax’.

Methods:

A documentation field study involving thirty individuals with a recorded history of non-specific insomnia complaints was conducted to determine the inhaler’s specific effects.

Results:

Upon the nightly use for one week, the odor inhaler strongly improved sleep quality and reduced symptoms associated with poor sleep. Depending on the dimensions tested, effect sizes ranged between 0.8 < d < 2.6. Strongest effects were found for ‘difficulty maintaining sleep’, ‘difficulty initiating sleep’ and ‘feeling recovered after sleeping’.

Conclusion:

The inhaler proved to be useful in mitigating sleep impairment. The effects were strongest in individuals reporting low sleep quality.
Ascorbic Acid in Health and Disease: A Review
Authors: Alur Ashwini , Das Paramita , Chikkamath Vinuth
Published: January 2021

:

Ascorbic acid is an essential nutrient, and required for various metabolic activities in humans.
Typically citrus fruits, vegetables and organ meat are good source of vitamin C. It acts as
strong antioxidant and act as a scavenger in defence against free radical oxygen species. It has also
contributed to rejuvenate photo aged skin. It has ability to control the pigmentation of melanin by
inhibiting the enzyme tyrosinase by interacting with copper ions. It serves as a co-antioxidant with
vitamin E to regenerate alpha tocopherol, thereby retards cellular damage. Ascorbic acid is deprotonated
to form ascorbate anion, contributes to its prooxidant properties and act as a potential anticancer
agent. It reduces the mutation rate in mismatch-repair deficient human colon cancer cells.
Ascorbic acid is a phytochemical has micronutrients that act against the inflammation in arthritis.
Currently, challenges lies finding most stable formulation for achieving optimum results.
Performance of Resins Based on Poly(Divinylbenzene-co-Methyl Methacrylate) for Removal of Calcium and Magnesium Ions from Water
Authors: Bernardo Camilla N. , Silva Carla Michele F. , Aguiar Paula F. , Lucas Elizabete F.
Published: January 2021

Background:

The mixing of the formation water present in oil and gas reservoirs and
the injected water (often seawater) can form inorganic incrustations, during enhanced oil recovery
operations. In this case, the cations (calcium, barium, strontium, iron, magnesium, etc.) of the injected
water react with the anions (mainly sulfate and carbonate) of the formation water and produce
inorganic salts that can precipitate in the reservoir rock, damaging the oil production by clogging
the pipes and production lines. One of the ways to prevent this problem is to remove the cations
from the injected water, but this is a challenging procedure.

Objective:

In this study, the Sulfonated polymer(divinylbenzene) (DVBS) and the copolymer sulfonated
poly(methyl methacrylate-co-divinylbenzene (MMA-DVB) were compared in their efficiencies
in reducing, to a very low level, the concentration of removing, chemically modified with sulfonic
(S) groups to ascertain their performance, the calcium and magnesium ions present in water.

Method:

The resins were modified with sulfonic groups and characterized. We used central composition planning with
batch tests to evaluate the adsorption, which occurred significantly for both ions using both resins with contact time of 10
minutes.

Results:

For both resins, calcium was preferentially adsorbed in relation to magnesium.

Conclusion:

Taking is account cost benefit, the copolymer MMA-DVBS (a less expensive adsorbent than the polymer
DVBS) presented a satisfactory behavior, making it a potential material for treatment of water.
Hydroxychloroquine Sulfate (Plaquenil): A Possible Candidate for Pandemic SARS-CoV-2 or (COVID-19)?
Authors: Chandra Subhash , Saklani Sarla , Aboul-Enein Hassan Y.
Published: January 2021

Hydroxychloroquine is a chloroquine derivative which is well recognized for its ‘SARS-CoV-2 or COVID-19’ &
other uses. It’s one of the key drugs of malaria and other various respiratory diseases. The drug exhibits a wide range of
activities that include strong antimalarial, antidibetic, anticancer, anti-HIV, antifungal, antimicrobial and antioxidant
activities. The based on latest study of corona virus, they have showed five mutations or genetic change in their structure,
due to change of their climatic condition (e. i. R 207C (nsp 2-27) – Wuhan (China), V 378 I (nsp 2- 198) – Italy, M 2796I (nsp
4- 33) – Iran, L 3606F (nsp 6- 37)-America and V 9082F (ORF 7a- 74) – Kuwait). Here is so many preclinical, clinical,
theoretical and experimental evidence, All these supports are directly related to the effectiveness of HCQ & CQ on patients
affected by COVID-19. Based on the evidence currently underway and future research, we will be able to provide better role
results in COVID-19 transition of HCQ and CQ. It displays several activities that are related to the respiratory system and
numerous studies have suggested that the compound may be beneficial to protect against disease such as malaria and lupus
erythematosus. The present review represents the role & use of HCQ as a COVID-19 disease. The object for this review
study is based on the research evidence obtained from different authentic sources and currently used for the treatment of
HCQ and CQ in the corona virus and various other infections.
Vraag en Antwoord
Authors: GT Gt
Published: January 2021

oa Het Klooster van Deinze, sedert 1793 Krijgsgasthuis
In memoriam Jean TYTGAT
Authors: GT Gt
Published: January 2021

1918 - 1993
Hoogstraat nr 54. drie FOTO's
Authors: Mauquoy Paul
Published: January 2021

De eerste twee foto's betreffen het huis Hoogstraat 54. Deze foto's werdenbeiden genomen vóór 1912.De derde foto betreft het huis Hoogstraat nr. 2.
Sobre el significado de los ajustes de procedimiento
Authors: De Asís Rafael
Published: January 2021

RESUMO:Este trabalho dá conta do significado dos ajustes processuais, mencionados no artigo 13 da Convenção sobre os Direitos das Pessoas com Deficiência. É um dos conteúdos do devido processo e está incluído no direito à acessibilidade.
A natureza do direito autoral: uma breve reflexão à luz da teoria dos direitos intelectuais
Authors: Bezerra Matheus Ferreira
Published: January 2021

RESUMO:O presente trabalho faz uma abordagem sobre a natureza da propriedade intelectual, em especial do direito autoral, que apresenta intensos debates doutrinários para a compreensão de sua essência. Neste sentido, são feitas abordagens acerca da teoria dos direitos intelectuais, e seus reflexos na classificação romana dos direitos, em busca de um sistema de proteção mais condizente com a realidade atual dos bens intelectuais, a partir de breve reflexões sobre a essência destes, a sua receptividade pelo direito e da aplicabilidade dos direitos reais sobre os mesmos.
Resenha da obra "Disability rights and wrongs revisited", de Tom Shakespeare
Authors: Sousa Alessandra Moraes de
Published: January 2021

RESUMO:Resenha do livro Disability rights and wrongs revisited. London: Routledge, 2014. 280p de Tom Shakespeare
La imposibilidad que existe en España de heredar a una persona con discapacidad por parte de aquellos que no le prestaron los alimentos que necesitaba
Authors: Botello Hermosa Pedro
Published: January 2021

RESUMO:Em 2003, o legislador espanhol introduziu uma série de medidas destinadas a proteger a propriedade das pessoas com deficiência. Uma dessas medidas é especificamente a que estamos estudando neste artigo: a condição de indigno na sucessão de uma pessoa com deficiência, por todo aquele que não tenha fornecido os alimentos necessários quando a pessoa com deficiência tiver deles necessitado.
Corpos, instituições e necropolítica: reflexões contemporâneas sobre a internação involuntária das pessoas com deficiência mental e as Comunidades Terapêuticas
Authors: Martins Laércio Melo
Published: January 2021

RESUMO:O objetivo do presente artigo é analisar a execução da internação involuntária a partir da Lei n. 13.840/2019, que trata sobre o Sistema Nacional de Políticas Públicas sobre Drogas, ao considerar inclusive a Lei 10.216/01 (Lei da Reforma Psiquiátrica). Nesse caminho, foi considerada a construção social do indivíduo no processo de subjetivação atravessado pelas instituições médico-jurídicas ao pensar o cuidado médico em liberdade da pessoa com deficiência mental usuária de álcool ou outras drogas na Rede de Atenção Psicossocial brasileira. Além disso, buscou-se realizar uma compreensão sobre o controle sociopolítico do corpo, a partir do método hipotético-dedutivo, bem como descritivo, teórico e analítico, através das instituições. Como resultado da análise em documentos legislativos, livros e artigos acadêmicos, observa-se a opção necropolítica do Estado brasileiro, ao fortalecer às Comunidades Terapêuticas, em detrimento dos Centros de Atenção Psicossocial.
Deficiência, mulheres e a dimensão do cuidado: compreensões das interseções em relações jurídico-sociais aplicadas
Authors: Marafon Giovanna , Piluso Roberta Pinheiro
Published: January 2021

RESUMO:Neste artigo buscamos compreender as intersecções possíveis entre os campos da deficiência e de gênero, por meio da proposta de um diálogo interseccional, que considera ainda outros marcadores sociais de diferença. Subsidiamos a discussão teórica em um olhar para o modelo social da deficiência, com o aporte fundamental do pensamento feminista em relação aos estudos da deficiência, especialmente pela centralidade atribuída à dimensão do cuidado e na contribuição da teoria crip. Realizamos análises jurídico-sociais a partir de duas experiências profissionais, a saber: na militância no campo jurídico em relação às pessoas com deficiência e na pesquisa-extensão universitária na formação e intervenção nos modos de compreensão da deficiência e da inclusão e mediação.
Editorial da seção especial "Pesquisadoras do Direito: nossas investigações, nossas produções acadêmicas”
Authors: Emerique Lilian Balmant , Achury Liliana Estupiñan , Storini Claudia
Published: January 2021

RESUMO: Editorial da seção especial "Pesquisadoras do Direito: nossas investigações, nossas produções acadêmicas”ABSTRACT:Editorial (Introduction to the Special Issue "Pesquisadoras do Direito: nossas investigações, nossas produções acadêmicas")
Direito à alimentação adequada e a medida provisória 870/2019: um estudo à luz da constitucionalidade
Authors: Almeida Sandra Oliveira de , Frozi Daniela Sanches
Published: January 2021

RESUMO:O presente estudo pretende refletir sobre a efetividade do Direito Humano à Alimentação Adequada no Estado Democrático de Direito à luz da teoria de justiça enquanto desenvolvimento das capacidades humanas, e a constitucionalidade da Medida Provisória (MP) n. 870, editada em 01 de janeiro de 2019, que revogou as disposições da Lei n. 11.346/06 referentes às atribuições e composição do Conselho de Segurança Alimentar e Nutricional (CONSEA), órgão de diálogo e participação social, que compõe um dos pilares do Sistema de Segurança Alimentar e Nutricional (SISAN). A pesquisa foi desenvolvida na abordagem qualitativa a partir da revisão crítica da literatura. A reorganização administrativa do novo governo por medida provisória é legítima, porém a extinção do órgão implicaria na inviabilidade do Sistema Nacional de Segurança Alimentar e Nutricional ao não transferir a outro ente suas competências, violando a dimensão organizativa dos Direitos Fundamentais. No cenário de fortes desigualdades, em um ambiente de baixa participação social, as ameaças poderiam desconstruir a ideia de Justiça a partir da lógica do bem-estar social, afetando a concretização do Direito Humano à Alimentação Adequada.
A justiça restaurativa como possibilidade de judicialização dos casos de estupro contra mulheres: uma alternativa ao sistema criminal punitivista
Authors: Moreira Lurine Guimarães Sandra Suely , Figueiredo Atanes Raissa
Published: January 2021

RESUMO:O presente trabalho, por meio de um estudo bibliográfico, tem como objetivo discutir a possibilidade de adotar a Justiça restaurativa nos casos de estupro contra mulheres. Isto porque o modelo tradicional de justiça criminal, declaradamente punitivista, tem como objetivo precípuo a adoção da punição sem considerar minimamente as necessidades das vítimas, que em regra é quase sempre vista como objeto probatório para fins de condenação ou absolvição do agressor. Como o estupro é uma forma de violência que deixa consequências indeléveis na vítima, e considerando o número elevado de casos de estupro contra mulheres no Brasil, há a necessidade de uma reflexão sobre a inadequação do sistema criminal punitivista e retributivo na judicialização dessa prática criminosa. Dentre outras coisas, o sistema criminal tende a reproduzir os estereótipos de gênero presentes no senso comum social, cuja consequência é a revitimização da mulher, ao culpabilizá-la pela violência da qual foi vítima. Por essa razão, é pertinente analisar se o modelo restaurativo, cujo cerne é a reparação e, portanto, prioriza as necessidades da vítima sem descurar do agressor, mostra-se uma alternativa adequada à abordagem do estupro.
Knowledge of OSTEOPOROSIS and LIFESTYLE BEHAVIOURS IMPACTING PEAK BONE MASS among Young Adults
Authors: Patel Hansa , Denison Hayley , Zafar Sana , Teesdale-Spittle Paul , Dennison Elaine ,   Victoria University of Wellington, School of Biological Sciences, New Zealand,   Southampton, MRC Lifecourse Epidemiology Unit, University of Southampton, United Kingdom
Published: January 2021

Osteoporosis is a major public health problem through its association with fragility fracture. Low peak bone mass (PBM) is a major contributor to later osteoporosis risk. Despite this, most studies concentrate on older people when the window of opportunity to impact PBM has passed. This study aimed to understand what adolescents and young adults understand about PBM, the risk of osteoporotic fracture and how lifestyle factors impact PBM. Such information may inform educational interventions to reduce future risk of fracture, and provide important public health benefits. New Zealand university students were approached to participate in this study. Nine focus groups of a total of 44 adolescents and young adults, mean age 22.9 (± 4.02) years of different ethnicities (29 female 15 male), were conducted using a semi-structured approach with open-ended questions and prompts. Transcripts were thematically coded using an inductive content analysis approach. Participants reported poor knowledge of PBM and factors impacting risk of osteoporotic fracture. There was a general awareness of the positive and negative impacts of many lifestyle behaviours such as physical activity, diet, tobacco smoking and alcohol consumption on health in general, but not specifically how these impact PBM and good bone health in later life. We conclude that in a cohort of New Zealand University students, current knowledge of osteoporosis and lifestyle factors that impact PBM is limited. Educational interventions in young adults are now warranted to improve PBM and prevent osteoporosis in late adulthood.
Testing the Digital Health Literacy Instrument for Adolescents: Cognitive Interviews
Authors: Park Eunhee , Kwon Misol
Published: January 2021

Background

Despite the increasing number of youth seeking health information on the internet, few studies have been conducted to measure digital health literacy in this population. The digital health literacy instrument (DHLI) is defined as a scale that measures the ability to operate digital devices and read and write in web-based modes, and it assesses seven subconstructs: operational skills, navigation skills, information searching, evaluating reliability, determining relevance, adding self-generated content to a web-based app, and protecting privacy. Currently, there is no validation process of this instrument among adolescents.

Objective

This study aims to explore the usability and content validity of DHLI.

Methods

Upon the approval of institutional review board protocol, cognitive interviews were conducted. A total of 34 adolescents aged 10-18 years (n=17, 50% female) participated in individual cognitive interviews. Two rounds of concurrent cognitive interviews were conducted to assess the content validity of DHLI using the thinking aloud method and probing questions.

Results

Clarity related to unclear wording, undefined technical terms, vague terms, and difficult vocabularies was a major issue identified. Problems related to potentially inappropriate assumptions were also identified. In addition, concerns related to recall bias and socially sensitive phenomena were raised. No issues regarding response options or instrument instructions were noted.

Conclusions

The initial round of interviews provided a potential resolution to the problems identified with comprehension and communication, whereas the second round prompted improvement in content validity. Dual rounds of cognitive interviews provided substantial insights into survey interpretation when introduced to US adolescents. This study examined the validity of the DHLI and suggests revision points for assessing adolescent digital health literacy.
Geographic Distribution of Mental Health Problems Among Chinese College Students During the COVID-19 Pandemic: Nationwide, Web-Based Survey Study
Authors: Wu Xiaoyan , Tao Shuman , Zhang Yi , Li Shiyue , Ma Le , Yu Yizhen , Sun Guilong , Li Tingting , Tao Fangbiao
Published: January 2021

Background

Since the COVID-19 outbreak was first reported, considerable attention has been drawn to mental health problems among college students.

Objective

We aimed to estimate the prevalence of anxiety and depressive symptoms among college students in different geographical areas of China during the early stage of the COVID-19 outbreak.

Methods

A nationwide cross-sectional survey was conducted among Chinese college students of 16 provinces or municipalities from February 4 to 12, 2020. A web-based survey was adopted to collect information from these college students, including demographics, perceived risk of infection, attitudes toward the epidemic and its control, and mental health status. Anxiety symptoms were assessed using the Generalized Anxiety Disorder scale, and depressive symptoms were assessed using the Patient Health Questionnaire. Chi-square test was used to compare the percentage of perceived risk of infection and attitude toward COVID-19 among college students in different geographic locations. Binary logistic models were used to identify associations between geographic locations and mental health problems after controlling for covariates.

Results

A total of 11,787 participants were analyzed in this study (response rate: 79.7%). The prevalence of anxiety and depressive symptoms among college students was 17.8% (95% CI 17.1%-18.5%) and 25.9% (95% CI 25.1%-26.7%), respectively. After controlling for covariates, current residence area in Wuhan city was found to have a positive association with anxiety symptoms (odds ratio [OR] 1.37, 95% CI 1.11-1.68) and depressive symptoms (OR 1.32, 95% CI 1.09-1.59). Similarly, college location in Wuhan city was found to have a positive association with anxiety symptoms (OR 1.20, 95% CI 1.07-1.35) and depressive symptoms (OR 1.22, 95% CI 1.10-1.36). History of residence in or travel to Wuhan city in the past month was also positively associated with anxiety symptoms (OR 1.62, 95% CI 1.46-1.80) and depressive symptoms (OR 1.48, 95% CI 1.35-1.63). Furthermore, the perceived risk of COVID-19 was higher among students whose college location and current residence area were in Wuhan city, and it was positively associated with anxiety and depressive symptoms.

Conclusions

During the COVID-19 pandemic, mental health problems among Chinese college students were widespread and geographically diverse. Our study results provide further insight for policymakers to develop targeted intervention strategies.
A Personal Health System for Self-Management of Congestive Heart Failure (HeartMan): Development, Technical Evaluation, and Proof-of-Concept Randomized Controlled Trial
Authors: Luštrek Mitja , Bohanec Marko , Cavero Barca Carlos , Ciancarelli Maria Costanza , Clays Els , Dawodu Amos Adeyemo , Derboven Jan , De Smedt Delphine , Dovgan Erik , Lampe Jure , Marino Flavia , Mlakar Miha , Pioggia Giovanni , Puddu Paolo Emilio , Rodríguez Juan Mario , Schiariti Michele , Slapničar Gašper , Slegers Karin , Tartarisco Gennaro , Valič Jakob , Vodopija Aljoša
Published: January 2021

Background

Congestive heart failure (CHF) is a disease that requires complex management involving multiple medications, exercise, and lifestyle changes. It mainly affects older patients with depression and anxiety, who commonly find management difficult. Existing mobile apps supporting the self-management of CHF have limited features and are inadequately validated.

Objective

The HeartMan project aims to develop a personal health system that would comprehensively address CHF self-management by using sensing devices and artificial intelligence methods. This paper presents the design of the system and reports on the accuracy of its patient-monitoring methods, overall effectiveness, and patient perceptions.

Methods

A mobile app was developed as the core of the HeartMan system, and the app was connected to a custom wristband and cloud services. The system features machine learning methods for patient monitoring: continuous blood pressure (BP) estimation, physical activity monitoring, and psychological profile recognition. These methods feed a decision support system that provides recommendations on physical health and psychological support. The system was designed using a human-centered methodology involving the patients throughout development. It was evaluated in a proof-of-concept trial with 56 patients.

Results

Fairly high accuracy of the patient-monitoring methods was observed. The mean absolute error of BP estimation was 9.0 mm Hg for systolic BP and 7.0 mm Hg for diastolic BP. The accuracy of psychological profile detection was 88.6%. The F-measure for physical activity recognition was 71%. The proof-of-concept clinical trial in 56 patients showed that the HeartMan system significantly improved self-care behavior (P=.02), whereas depression and anxiety rates were significantly reduced (P<.001), as were perceived sexual problems (P=.01). According to the Unified Theory of Acceptance and Use of Technology questionnaire, a positive attitude toward HeartMan was seen among end users, resulting in increased awareness, self-monitoring, and empowerment.

Conclusions

The HeartMan project combined a range of advanced technologies with human-centered design to develop a complex system that was shown to help patients with CHF. More psychological than physical benefits were observed.

Trial Registration

ClinicalTrials.gov NCT03497871; https://clinicaltrials.gov/ct2/history/NCT03497871.

International Registered Report Identifier (IRRID)

RR2-10.1186/s12872-018-0921-2
Relationship between Perceived Parenting Styles of Mothers and Emotional Intelligence Among Undergraduate Students
Authors: Fatima Kashif Dr. Mahvish , Shaheen Dr. Faiza , Tahir Maryam
Published: January 2021

The objective of the study was to find out relationship between perceived parenting styles of mothers and emotional intelligence among undergraduate students. Correlational research was selected as research design. The population of the study was undergraduate students of education department of public and private universities of Lahore. The total population was 1760. Proportionate stratified random sampling technique was used to select the sample. The strata were formed on the basis of nature of the university. The total number of students selected was 528. The instrument consisted of three parts; first part consisted of demographic information (gender, nature of institution, education of mother and working status of mother). The second part consisted of Parenting Authority Questionnaire (PAQ), designed by Buri (1991) which was used to measure parenting styles and the third part consisted of Emotional Intelligence questionnaire (EI) by Schutte (1998) which was used to measure emotional intelligence. Data was collected individually from participants through questionnaires by survey method. Both inferential and descriptive statistics were applied to analyze the data. Multiple regression analysis was used to determine the relationship between the variables and Independent sample t-test was used to determine the difference between the demographic variables.
La resiliencia bibliotecaria como herramienta fundamental ante las crisis
Authors: Espino Rivera María Del Rocío , Rivera Espino Mary Carmen
Published: January 2021

La resiliencia es aún un concepto en construcción, ve sus inicios con los trabajos de Emmy Werner y se afianza con contribuciones como la de Edith Grotberg con sus palabras de poder o las 7c ́s de Horne y Orr; aquí se propone un concepto incluyente de la resiliencia en acción, ya que la resignación o adaptación sin acción no representan la esencia de lo que es la resiliencia. Es así que se abordan los tres momentos de la resiliencia en acción desde la perspectiva de fortalecimiento individual, pero también se traslada al ámbito bibliotecario, recordando que actualmente las organizaciones de todo el mundo incluyen en sus administraciones modelos de resiliencia organizacional. Se brinda un panorama de la manera en que la biología de nuestro cuerpo está viviendo las adversidades pandémicas y de cómo estamos diseñados también para trascender el momento de crisis. Se propone en este ensayo un modelo específico para ser aplicado a las bibliotecas, el cual hemos denominado mar-b (Modelo de Acción Resiliente Bibliotecaria), explicando los beneficios de su implementación y destacando los elementos que conforman su característica principal, la cual es el cuidado resiliente. Se concluye señalando el momento imperante de atender la incertidumbre que ha generado la pandemia a fin de lograr la trascendencia resiliente.
Securitization on the Spread of COVID-19 in Indonesia [Sekuritasasi dalam Penyebaran Covid-19 di Indonesia]
Authors: Tifany Cornelia Clara
Published: January 2021

Based on the World Health Organization report, Coronavirus disease 2019 (COVID-19) is an infectious respiratory disease that has become an epidemic in approximately 213 countries throughout the world, including Indonesia. Prior to the first confirmed case of COVID-19 in Indonesia, the Indonesian government’s response, as represented by its high-level officials, suggested a lack of awareness. Some situations then became the turning points for the Indonesian Government, who has since focused more on dealing with the COVID-19 outbreak. Through this research, the writer aims to analyze the Indonesian Government’s treatment of COVID-19 from a health issue to a security issue. Therefore, the securitization theory focusing on the component of securitization from Buzan will be employed as an analytical framework in this research. In addition, the global health governance is also used as a reference to support the writer’s statement. In order to explain the action of the Indonesian Government, this research will use qualitative research with a focus on literacy observations through online news relating to the issues. In conclusion, the change in action of the Indonesian Government was caused by the pressure from GHG, which then showed that the spread of COVID-19 in Indonesia is a security issue.AbstrakCoronavirus disease (COVID-19) yang merupakan penyakit pernapasan menular telah mewabah kurang lebih di 213 negara di dunia berdasarkan pada laporan World Health Organization, salah satu negara yang terkena wabah adalah Indonesia. Sebelum ada konfirmasi atas kasus COVID-19 di Indonesia, terlihat sikap pihak pemerintah yang diwakili oleh pejabat tinggi menunjukkan sikap kurang perhatian. Namun beberapa situasi menjadi “turning point” bagi Pemerintah Indonesia yang kemudian memberikan fokus yang lebih dalam menghadapi wabah COVID-19 di Indonesia. Dari keadaan tersebut melalui penelitian ini, penulis menganalisis sikap Pemerintah Indonesia dalam mengubah isu kesehatan menjadi isu keamanan. Penelitian ini menggunakan teori sekuritisasi sebagai kerangka analisis dengan terfokus pada komponen sekuritisasi oleh Buzan. Di samping itu juga menggunakan tata kelola kesehatan global sebagai penopang pernyataan penulis. Agar mampu menjelaskan sikap Pemerintah Indonesia maka penelitian ini menggunakan metode penelitian kualitatif dengan fokus pada pengamatan literasi melalui berita daring yang berkaitan dengan permasalahan yang diangkat. Dalam kesimpulannya, perubahan sikap Pemerintah Indonesia disebabkan oleh adanya tekanan dari tata kelola kesehatan global yang menunjukkan bahwa penyebaran COVID-19 di Indonesia merupakan isu keamanan.
MALATYA TÜRKÜLERİNİN KEMAN EĞİTİMİNDE KULLANILMASI ÜZERİNE BİR ÇALIŞMA
Authors: AKBUDAK Hayri , AKPINAR Mehmet
Published: January 2021

Bu araştırmanın genel amacı, Malatya türkülerinin evrensel bir çalgı olan keman ile akademik bir düzeyde sistemli ve bilimsel olarak seslendirilme ve yorumlanma yöntemlerinin araştırılmasıdır. Bu amaçla hem araştırmada kullanılan verileri toplamak, hem de Malatya türkülerini oluşturan kaynaklara ulaşmak için literatür taraması yapılmıştır Türkiye Radyo Televizyon (TRT) Kurumu repertuarında yer alan Malatya türküleri incelenmiş ve bu türkülerden keman eğitimi için uygun olduğu düşünülen 6 türkü örneklem grubu olarak ele alınmıştır. Daha sonra türküler üzerinde yay teknikleri, parmak numaraları ve konum geçişleri ile ilgili bazı çalışmalar yapılmıştır. Yapılan bu çalışmalar alanında uzman olan bazı eğitimcilerle paylaşılmış ve onların görüşleri doğrultusunda gerekli görülen düzeltmeler yapılarak, I. Konumu kapsayan türküler 1. Düzey, I ve II. Konumu kapsayan türküler 2. Düzey I, II ve III. Konumu kapsayan türküler ise 3. Düzey olarak belirlenmiştir. Türkülerin notaya alınması ve düzenlenmesinde Sibelius 7.5 programı kullanılmıştır.
The use of interactive mnemonics for the development of communication skills of preschoolers
Authors: Builina Elena E. , Rudakova Dora T.
Published: January 2021

Problem and purpose. The experience of using mnemonics as a set of methods and techniques in preschool institutions is considered. The purpose of the described research is to ensure the most effective mastering by preschoolers of ideas about the world around them and the development of speech. Methodology. In the course of the research, the analysis of normative documents, psychological and pedagogical experience in the use of mnemonics was carried out, a generalization and systematization of the material on this topic was made, the reflection of the content of the formed knowledge has been done. Results. A proven method of using mnemonics in a preschool institution for the development of speech and understanding the features of the surrounding world is proposed. Step-by-step recommendations are formulated for the implementation of this technology in the organization of the activities of preschoolers. The psychological features of the use of mnemonic techniques, which contribute to the development of not only communication skills, but also the creative activity of children, are revealed. Conclusion. It is shown that the technique of using mnemonics has great potential and should be recommended for dissemination in work with a variety of groups of children with developmental features. At the same time, it was revealed that today in preschool institutions, mnemonics is used mainly in the traditional format, while the integration of the methodology with interactive information technologies is effective. The results of the study allow to draw conclusions about the prospects of the direction of interactive technology of mnemonics, which is faced with a problem of the level of readiness of employees of children's institutions to use them. In general, the research materials confirm that the integration of mnemonic techniques into the play activity of preschoolers corresponds to the age characteristics of children, contributes to the development of creativity, mutual understanding, deepening of interest and curiosity in the world around them.
Methods of teaching inverse and incorrect problems to students in the context of informatization of education
Authors: Kornilov Viktor S.
Published: January 2021

Problem and goal. Computer technologies are now widely used in applied research aimed at obtaining new scientific knowledge. These studies used the method of computer modeling and computing experiment, from which it is possible to study the properties of remote or inaccessible objects, processes and phenomena of different nature. The above mentioned is directly related to teaching students applied mathematics in general, and, in particular, to teaching students of physical and mathematical training areas inverse and ill-posed problems, which are the scientific direction of applied mathematics. It is obvious that in the process of teaching students inverse and ill-posed problems, it is advisable to use computer technologies. However, the use of computer technology should be appropriate and correct. Methodology. The process of finding solutions to inverse and ill-posed problems is usually time-consuming, since such mathematical problems are non-linear in their formulation and may have a non-unique and unstable solution. These circumstances pose a mathematical difficulty in the proof of the theorems of existence, uniqueness and stability of solutions to inverse and ill-posed problems. Computer technologies help to overcome mathematical difficulties associated with routine transformations, analysis of information about solving such mathematical problems. Results. Using computer technologies, students gain experience in mobile research of various inverse and ill-posed problems, as well as in identifying the capabilities of computer technologies in solving various applied mathematical problems, and develop ICT competence. Conclusion. When using multimedia and computer technologies in the process of teaching students inverse and ill-posed problems, didactic principles of teaching are implemented, which allow students to acquire deep scientific knowledge on inverse and ill-posed problems, and develop their information culture.
Positive Psychology Celebrates its 20th Anniversary!
Authors: Rich Grant J. , Kurilenko Victoria B. , Novikova Irina A.
Published: January 2021

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Meaning-Making, Forgiveness, and Gratitude: Nurturing a Healthy, Peaceful, and Prosperous Haiti
Authors: Kalayjian Ani
Published: January 2021

We have witnessed the growth and resilience of the Haitian people since 2010 and the devastating earthquake, in over fourteen humanitarian missions. In addition, MeaningfulWorld’s global presence, which aims to raise consciousness and nurture resilience and sustainability among local and global communities in Haiti, has highlighted perspectives from vulnerable and marginalized groups including children, women, and traumatized refugees. The results of this work has addressed the ultimate question in resolving emotional and psychological scars and promoting meaning, healing, hope, reconciliation, and trust: what lessons have we learned from our traumatic past? For MeaningfulWorld ambassadors, the only healthy and permanent means of resolution for past traumas is through integration of emotional intelligence (EQ), spiritual connections, love, meaning-making, forgiveness, and empathy, and nurturing gratitude as a basic foundation. This paper will describe the value of cultivating gratitude as a foundation and utilizing forgiveness and meaning-making through post trauma growth, building resilience, and emotional intelligence. Although historically Haiti has shown resilience, while the lessons learned are not only unclear, it is fragmented, misguided, and focused on fear derived from mass spread of horizontal violence, where the majority of the Haitian population pull one another down, and call it the ‘Haitian disease.’
Selection of Educational Routes by High School and College Graduates: A Positive Psychology Approach
Authors: Lubovsky Dmitry V.
Published: January 2021

Utilizing both perspectives from modern positive psychology and common, conventional theories, this article examines how graduates of high schools and colleges choose individual educational routes (IER). The significance of the issue of choosing IERs is discussed; additionally, the current state of research in this area is described. Methodological difficulties were revealed in the study of the choice of IERs by graduates of high schools and colleges and in the practice of psychological and pedagogical support for choice. Major contradictions and unresolved problems were identified in the theory and practice of psychological and pedagogical support for graduates of high schools and colleges in choosing their IERs. The most important data and findings on the choice of IERs made by modern high school and college students are presented, contradictions in the available data are revealed, and the specific features in disabled students’ choosing IERs are described. In addition, an analysis of the main approaches to studies of students’ choice of IERs (sociological, subjective and based on positive psychology) was conducted. Furthermore, the importance of positive psychology for solving existing problems in research and in the practice of psychological and pedagogical support for graduates of high schools and colleges in choosing IERs was described. The article provides a brief overview of recent positive psychology research on the choice of educational routes, and outlines the prospects for its application in solving urgent research and practical problems related to psychological and pedagogical support for students’ choice of IERs.
Wisdom as a Factor in Preventing Emotional Burnout among Medical Professionals
Authors: Mekhtikhanova Natalya N. , Murzina Julia S. , Rusakova Julia E.
Published: January 2021

The authors of this article examine wisdom as an internal resource in a sample of medical workers that can prevent the development of unhealthy deviations and preserve professional and life longevity. The aim of this work was to study the relationship between wisdom and emotional burnout in medical personnel. The article provides a theoretical analysis of the study of emotional burnout in medical workers, offers a description of the phenomenon of wisdom, and describes foreign empirical research on wisdom in the medical field. To collect data, the authors used The Level of Wisdom Questionnaire by N.N. Mehtikhanova and The Inventory for Diagnosing Emotional Burnout by V.V. Boyko. An empirical study conducted with 184 employees of the Tyumen Regional Clinical Hospital found signs of emotional burnout in 53.8% of the respondents. A comparison of groups of the surveyed medical workers having different levels of emotional burnout revealed significant differences in terms of wisdom. A correlation analysis showed a negative relationship between wisdom and emotional burnout of the medical personnel ( rs = -0.48, p 0.001). A comparison between the groups of male and female respondents showed significant differences in terms of wisdom ( U = 1267.50, p = 0.016) and in terms of emotional burnout ( U = 1253.00, p = 0.013): wisdom was higher in the group of men, while emotional burnout was higher in the group of women. A pairwise comparison using the Mann - Whitney U -test revealed differences in wisdom between the groups of junior medical personnel and managers ( U = 31.00, p = 0.007) as well as between the groups of nurses and managers ( U = 326.00, p 0.001). Wisdom in both cases was higher for the group of managers. In sum, results of this study found that wisdom helps medical personnel resist burnout syndrome. The formation of this quality will help medical workers to better preserve their mental health and professional longevity.