bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring patient perspectives: A qualitative inquiry into healthcare perceptions, experiences and satisfaction in Lebanon
Authors: Khalife Jade , Ekman Björn , Ammar Walid , El-Jardali Fadi , Al Halabi Abeer , Barakat Elise , Emmelin Maria
Published: August 2023

Background

Patient perspectives have received increasing importance within health systems over the past four decades. Measures of patient experience and satisfaction are commonly used. However, these measures do not capture all the information that is available through engaging with patients. An improved understanding of the various types of patient perspectives and the distinctions between them is needed. The lack of such knowledge limits the usefulness of including patient perspectives as components within pay-for-performance initiatives. This study aimed to explore patient perspectives on hospital care in Lebanon. It also aimed to contribute insights that may improve the national pay-for-performance initiative and to the knowledge on engaging patients towards person-centered health systems.

Methods

We conducted a qualitative study using focus group discussions with persons recently discharged after hospitalization under the coverage of the Lebanese Ministry of Public Health. This study was implemented in 2017 and involved 42 participants across eight focus groups. Qualitative content analysis was used to analyze the information provided by participants.

Results

Five overall themes supported by 17 categories were identified, capturing the meaning of the participants’ perspectives: health is everything; being turned into second class citizens; money and personal connections make all the difference; wanting to be treated with dignity and respect; and tolerating letdown, for the sake of right treatment. The most frequently prioritized statement in a ranking exercise regarding patient satisfaction was regular contact with the patient’s doctor.

Conclusions

Patient perspectives include more than what is traditionally incorporated in measures of patient satisfaction and experience. Patient valuing of health and their perceptions on each of the health system, and access and quality of care should also be taken into account. Hospital pay-for-performance initiatives can be made more responsive through a broader consideration of these perspectives. More broadly, health systems would benefit from wider engagement of patients. We propose a framework relating patient perspectives to value-based healthcare and health system performance.
Prognostic value of coronary atherosclerosis and CAC score for the risk of chemotherapy-related cardiac dysfunction (CTRCD): The protocol of ANTEC study
Authors: Borowiec Anna , Ozdowska Patrycja , Rosinska Magdalena , Jagiello-Gruszfeld Agnieszka , Jasek Slawomir , Waniewska Joanna , Kotowicz Beata , Kosela-Paterczyk Hanna , Lampka Elzbieta , Makowka Agata , Fuksiewicz Małgorzata , Chojnacka Magdalena , Zebrowska Agnieszka , Gepner Katarzyna , Kapala Aleksandra , Cieszanowski Andrzej , Nowecki Zbigniew , Walewski Jan
Published: August 2023

Background

Cardiological complications of oncological treatment, including the most serious one, heart failure, constitute a significant and still unsolved clinical problem. A history of dyslipidemia and complications of atherosclerosis, including coronary artery disease, are established risk factors for cardiotoxicity in cancer patients. In recent years, a protective effect of statin treatment on the development of heart failure in cancer patients has been observed. This protocol describes a study aiming to assess the prognostic value of coronary atherosclerosis burden and the CAC score on the onset of cardiac dysfunction associated with cancer therapy.

Methods

ANTEC (Atherosclerosis iN chemoTherapy-rElated Cardiotoxicity) is a single-site, prospective, observational study to evaluate the influence of the coronary atherosclerosis and CAC score assessed by computed tomography on the development of left ventricular systolic dysfunction in cancer patients with at least moderate cardiotoxicity risk. A group of 80 patients diagnosed with cancer prior to high-dose anthracycline chemotherapy (doxorubicin ≥ 240 mg / m2 body weight or epirubicin ≥ 600 mg / m2 body weight), without a history of heart failure and coronary artery disease, will be included in the study. Patient follow-up is planned for 12 months. In all patients, coronary computed tomographic angiography (CCTA) will be performed once at the beginning of the study. The primary endpoint is the onset of cancer therapy-related cardiovascular toxicity, defined as mild, moderate, severe and very severe according to ESC 2022 Cardio-oncology guidelines. During follow up, echocardiography with GLS assessment will be performed every three months. Additionally, new biomarkers of atherosclerosis (IL-6, MPO, TNF-alpha) will be measured every 6 months. The study registration identifier on clinicaltrials.gov is NCT05118178.

Clinical trials registry

This study is listed on cinicaltrials.gov with identifier NCT05118178.
Analysis of the spatial and temporal evolution process and development trend of innovation capability of Chinese sports industry
Authors: Chen Jiang , Cai ChuanMing , Zhang TingTing
Published: August 2023

The paper uses spatial panel data on the number of patents in the field of sports in each province from 2017–2022 to explore the spatial and temporal evolution process of the innovation capacity of China’s sports industry and analyze its development trend based on theories related to economic geography, using exploratory spatial data analysis (ESDA) and Spatial-temporal correlation analysis research methods. The study shows that: 1. there is a large spatial regional disparity in the innovation capacity of China’s sports industry, showing an obvious pattern of strength in the east and weakness in the west. 2. there is an obvious phenomenon of spatial agglomeration in the innovation capacity of China’s sports industry and the agglomeration phenomenon in space is gradually increasing. 3. there is a spatial spillover effect in the innovation capacity of China’s sports industry, and the inward spillover continues to strengthen mainly into Zhejiang, Fujian and Jiangsu provinces, while the outward spillover mainly goes to Guangdong, Hubei, Hebei, Hunan, Sichuan. Sports industry innovation capacity development put forward three suggestions: to promote the development of sports industry in the northwest region; to play the advantages of regional characteristics of sports industry; to accelerate the integration of neighboring regions to build the process. in order to help the high-quality development of sports industry.
Utility of the angle between the cervical canal and the anatomical conjugate line for predicting pouch of Douglas obliteration in patients with posterior placenta previa
Authors: Shinohara Satoshi , Kasai Mayuko , Yasuda Genki , Sunami Rei
Published: August 2023

Aim

Pouch of Douglas obliteration, which prevents exteriorization of the uterus, increases surgical morbidity in patients with placenta previa. We aimed to identify magnetic resonance imaging features that can predict pouch of Douglas obliteration preoperatively.

Methods

We retrospectively assessed 39 women with posterior placenta previa who underwent magnetic resonance imaging for the preoperative assessment of placenta accreta spectrum. We defined the angle formed by the anatomical conjugate line (based on pelvimetry) and the cervical canal as the cervical inclination angle, which was measured on sagittal T2-weighted magnetic resonance imaging. Subsequently, we analyzed the correlation between the cervical inclination angle and pouch of Douglas obliteration.

Results

The median maternal age was 34 years (range, 22–44 years) and 26 (66.7%) women delivered at term. The median cervical inclination angle was 98° (range, 71–128). Pouch of Douglas obliteration was confirmed in six patients (15.4%). The cut-off value of the cervical inclination angle for the prediction of pouch of Douglas obliteration was 102° with a sensitivity of 66.7%, specificity of 78.8%, positive predictive value of 36.4%, and negative predictive value of 92.9% (area under the curve, 0.83).

Conclusions

Measuring the cervical inclination angle may help in ruling out an obliteration of the pouch of Douglas. It may also be useful in the operative management of women with posterior placenta previa. However, caution should be exercised when generalizing the results of this study because of the small sample size, which makes the results prone to bias.
The impact of public environmental concern on environmental pollution: The moderating effect of government environmental regulation
Authors: Liu Nengyu , Liu Yue , Yu Xiaofei
Published: August 2023

As environmental problems continue to intensify, public environmental awareness and participation have become key forces in a modernized environmental governance system. Recognizing the importance of public participation in environmental governance, this study explores the influence of public pressure on environmental pollution and its implications for China’s long-term environmental management efforts. Using statistical and internet search data from 284 prefecture-level cities between 2011 and 2020, the study finds that a 1% increase in public environmental concern leads to a 0.009% reduction in pollution. The study also highlights the strengthening effect of government environmental regulation on the impact of public environmental concern. Moreover, regional heterogeneity analysis reveals a stronger effect of public environmental concern in cities facing low economic pressure. The findings of the study provide a reference for the construction of a coordinated and sustainable environmental governance model in China as well as in developing countries.
This is Africa: How young African TikTok trends challenged Afropessimism during COVID-19
Authors: Machirori Fungai
Published: August 2023

Afropessimism, or the western media tradition of covering Africa in stereotypically negative ways, has continually served to strip the continent of representational nuance and agency. While Africa experienced its own COVID-19 challenges during the pandemic, the Afropessimistic outlook of total collapse and carnage did not become a reality. In fact, with the popular uptake of TikTok as the pandemic wore on, Africans began social media trends that kept many globally entertained as they navigated new lockdown realities. This study looks at three of these TikTok trends, namely #JerusalemaChallenge, #DontRushChallenge and #DontLeaveMeChallenge. Through textual analysis, the study explores if and how these trends provided counternarratives to Afropessimism. With dominant themes such as humour and dance emerging, findings suggest that these trends offered content that can be read as contributing to challenging Afropessimism through cultivating African digital agency and representation.
Effect of TG5 and LEP polymorphisms on the productivity, chemical composition, and fatty acid profile of meat from Simmental bulls
Authors: Sycheva Irina , Latynina Evgeniya , Mamedov Azer , Tsibizova Oksana , Kozak Yulia , Svistounov Dmitriy , Bystrenina Irina , Orishev Aleksandr
Published: August 2023

Background and Aim: Enhancing the nutritional and biological value of meat obtained from young surplus replacement animals of dual-purpose breeds is a critical objective in the livestock industry. This study aimed to investigate the impact of thyroglobulin (TG5, c. −422C > T) and leptin (LEP, c. 239C > T) polymorphisms on the productivity, chemical composition, and fatty acid (FA) profile of meat from Simmental bulls. Materials and Methods: A total of 26 Simmental bulls were genotyped for TG5 (c. −422C > T) and LEP (c. 239C > T) polymorphisms and reared under the same fattening conditions. Controlled slaughter was conducted at 18 months of age. Subsequently, the experimental animals were evaluated to determine their slaughter traits and the chemical and FA composition of ground beef and the longissimus dorsi muscle. Results: The results showed that the TG5 (c. −422C > T) polymorphism significantly (p < 0.05) affected the differentiation of bulls in terms of the synthesis of stearic acid, linolenic acid, and total polyunsaturated FAs, as well as the fat and dry matter content in the longissimus dorsi muscle. Conversely, the presence of the T allele in the LEP (c. 239C > T) polymorphism was associated with increased dry matter and fat in ground beef, carcass weight, and internal fat weight. Conclusion: The analysis of slaughter traits and the chemical and FA composition of meat from the Simmental bulls genotyped for the TG5 and LEP genes revealed a genetic basis for the quantitative and qualitative characteristics of meat productivity. Thus, the genetic variability of bulls regarding the LEP and TG5 genes can be used to improve the quantitative and qualitative indicators of meat productivity in Simmental cattle through marker-assisted selection. Keywords: chemical composition, fatty acid, leptin, meat productivity, polymorphism, Simmental, thyroglobulin.
Parameter estimation in non-linear chemical processes: an opposite point-based differential evolution (OPDE) approach
Authors: Yadav Swati , Angira Rakesh
Published: August 2023

In recent years, evolutionary algorithms have been gaining popularity for finding optimal solutions to non-linear multimodal problems encountered in many engineering disciplines. Differential evolution (DE), an evolutionary algorithm, is a novel optimization method capable of handling nondifferentiable, non-linear, and multimodal objective functions. DE is an efficient, effective, and robust evolutionary optimization method. Still, DE takes large computational time to optimize the computationally expensive objective functions. Therefore, an attempt to speed up DE is considered necessary. This paper introduces a modification to the original DE that enhances the convergence rate without compromising solution quality. The proposed opposite point-based differential evolution (OPDE) algorithm utilizes opposite point-based population initialization, in addition to random initialization. Such an improvement reduces computational effort. The OPDE has been applied to benchmark test functions and high-dimensional non-linear chemical engineering problems. The proposed method of population initialization accelerates the convergence speed of DE, as indicated by the results obtained using benchmark test functions and non-linear chemical engineering problems.
How Linguistic Data Can Inform Archaeological Investigations: An Australian Pilot Study Around Combustion Features
Authors: Ward Ingrid , Ponsonnet Maïa , Miceli Luisa , Dotte-Sarout Emilie , Rustandi Jason
Published: August 2023

We present an interdisciplinary collaboration whereby linguistic data are explored with the aim of gaining new insights on archaeological features to enrich investigations of the past. Archaeology on its own relies on a very discontinuous record and here we argue that a fuller use of linguistic resources can offer more nuanced insights of the cultural context, and thus a more comprehensive reconstruction of both archaeological histories in general and archaeological features specifically. Languages, as complex human artefacts, often develop vocabularies that reflect speakers’ need to communicate about everyday objects and actions. Therefore, it makes sense to turn to lexicographic and semantic data as sources of additional clues about various aspects of the past. To date, this kind of collaboration has either focused on aspects of culture that leave little trace in the archaeological record or on aspects of material culture that informs wider histories of migrations and contacts. Collaboration has also, more often than not, had the goal of answering linguistic rather than archaeological questions. The novel approach we propose here is a focus on a domain which does leave a substantial trace in the archaeological record and that falls in the realm of mundane aspects of the universal human experience – i.e. domestic fire use – with the aim of gaining a more nuanced and culturally grounded understanding of archaeological features and their investigation. This article is a demonstration in principle for the potential of this approach, illustrated here with a pilot study of combustion features on the Australian continent. Having collected fire-related words in a sample of dictionaries of Australian Indigenous languages, we explain how and why the information they encapsulate can support archaeological studies.
Laboratory Testing of Ferrochrome Slag as an Aggregate in Porous Pavements
Authors: Topaloglu Sedat , Cetin Altan , Dayioglu Asli Y. , Aydilek Ahmet H.
Published: August 2023

Porous asphalt (PA) is a bituminous mixture that is preferred in surface wearing courses because of its comparably better skid resistance and reduced spraying and hydroplaning risk, leading to improved driving quality compared with dense-graded hot mix asphalt mixtures. Use of recycled materials with satisfactory strength and durability properties as an aggregate in PA mixtures would provide both economic and environmental benefits because natural resources would be preserved, and transportation costs, and consequently CO2 emissions, would be reduced, and the stockpiled recycled material would be employed instead of occupying scarce landscape. However, because of the high air void content and exposure of a larger surface area to atmosphere in PA mixtures, the potential for raveling and rapid aging for any proposed aggregate material needs to be evaluated carefully. This study was conducted to investigate the performance of ferrochrome slag (FS), a by-product of ferrochromium industries, as an aggregate in porous asphalt. Air voids content, permeability, particle loss, tensile strength, and moisture susceptibility were measured on three different gradations of FS and the results were compared with the limits given in construction specifications. The gradation of the slag aggregates along with the bitumen content played a key role on performance of the PA mixtures. The FS specimens prepared at an optimum bitumen content of 6.5 % performed significantly better than limestone (LS) aggregate specimens at the same gradation; the air void content, permeability, and tensile strength of the FS mixtures were 2 %, 50 %, and 16 % higher than the LS mixtures, respectively.
Rapid Audiovisual Integration Guides Predictive Actions
Authors: Kreyenmeier Philipp , Schroeger Anna , Cañal-Bruland Rouwen , Raab Markus , Spering Miriam
Published: August 2023

Natural movements, such as catching a ball or capturing prey, typically involve multiple senses. Yet, laboratory studies on human movements commonly focus solely on vision and ignore sound. Here, we ask how visual and auditory signals are integrated to guide interceptive movements. Human observers tracked the brief launch of a simulated baseball, randomly paired with batting sounds of varying intensities, and made a quick pointing movement at the ball. Movement end points revealed systematic overestimation of target speed when the ball launch was paired with a loud versus a quiet sound, although sound was never informative. This effect was modulated by the availability of visual information; sounds biased interception when the visual presentation duration of the ball was short. Amplitude of the first catch-up saccade, occurring ∼125 ms after target launch, revealed early integration of audiovisual information for trajectory estimation. This sound-induced bias was reversed during later predictive saccades when more visual information was available. Our findings suggest that auditory and visual signals are integrated to guide interception and that this integration process must occur early at a neural site that receives auditory and visual signals within an ultrashort time span.
Hospital overcrowding caused by covid-19 and chronic kidney disease mortality
Authors: Yang Yang , Zurbenko Igor
Published: August 2023

The coronavirus disease (COVID-19) pandemic has been the largest public health emergency in recent decades. While there have been many epidemiology studies on this pandemic, less research has been done to examine its indirect impact on mortality. This paper utilizes Kolmogorov-Zurbenko (KZ) filter to examine chronic kidney disease (CKD) mortality trend in Florida hospitals and finds an indirect impact of the pandemic, namely the excess Florida CKD deaths due to pandemic-period hospital over-crowding. The results show that kidney disease patients suffer higher mortality from hospital overcrowding, thus prompting the need to allocate healthcare resource to more vulnerable patients. This paper also proposes a measurement method of hospital overcrowding with KZ filter. The strong correlation between CKD mortality and hospital overcrowding confirms that the level of healthcare has a significant influence on the wellness of CKD patients.
Descompresión artroscópica para la neuropatía del nervio supraescapular. Reporte de un caso y revisión anatómica
Authors: Cullari Matías Leonardo , Gómez Diego José , Veloz Serrano Daniel , Moya Daniel
Published: August 2023

La neuropatía del nervio supraescapular es una causa poco común de dolor y debilidad en el hombro y, por lo tanto, a menudo, es mal diagnosticada. Como consecuencia, el diagnóstico erróneo puede llevar a indicar un tratamiento conservador inapropiado o un procedimiento quirúrgico fallido. Se presenta el caso de un hombre de 55 años con síndrome de atrapamiento del nervio supraescapular. El paciente fue sometido a una artroscopia de hombro y se le diagnosticó una compresión del nervio supraescapular por el ligamento transverso escapular superior. La liberación artroscópica del nervio supraescapular alivió el dolor, la debilidad y la atrofia de los músculos supraespinoso e infraespinoso.
Dr. Gastón Maignon (1950-2023)
Authors: Moya Daniel
Published: August 2023

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Neonatal Admission Temperature in Middle- and High-Income Countries
Authors: Frade Garcia Alejandro , Edwards Erika M. , de Andrade Lopes José Maria , Tooke Lloyd , Assenga Evelyne , Ehret Danielle E. Y. , Hansen Anne
Published: August 2023

BACKGROUND AND OBJECTIVES

Despite being preventable, neonatal hypothermia remains common. We hypothesized that the proportion of newborns with hypothermia on admission would be high in all settings, higher in hospitals in middle-income countries (MIC) compared with high-income countries (HIC), and associated with morbidity and mortality.

METHODS

Using the Vermont Oxford Network database of newborns with birth weights 401 to 1500 g or 22 to 29 weeks’ gestational age from 2018 to 2021, we analyzed maternal and infant characteristics, delivery room management, and outcomes by temperature within 1 hour of admission to the NICU in 12 MICs and 22 HICs.

RESULTS

Among 201 046 newborns, hypothermia was more common in MIC hospitals (64.0%) compared with HIC hospitals (28.6%). Lower birth weight, small for gestational age status, and prolonged resuscitation were perinatal risk factors for hypothermia. The mortality was doubled for hypothermic compared with euthermic newborns in MICs (24.7% and 15.4%) and HICs (12.7% and 7.6%) hospitals. After adjusting for confounders, the relative risk of death among hypothermic newborns compared with euthermic newborns was 1.21 (95% confidence interval 1.09–1.33) in MICs and 1.26 (95% confidence interval 1.21–1.31) in HICs. Every 1°C increase in admission temperature was associated with a 9% and 10% decrease in mortality risk in MICs and HICs, respectively.

CONCLUSIONS

In this large sample of newborns across MICs and HICs, hypothermia remains common and is strongly associated with mortality. The profound burden of hypothermia presents an opportunity for strategies to improve outcomes and achieve the neonatal 2030 Sustainable Development Goal.
Dataset for experiment 1 of A novel validation approach shows new, solid reasons why vertical jump height should not be used to predict leg power
Authors: Aragón-Vargas Luis Fernando , González-Lutz María Isabel
Published: August 2023

Jump height continues to be widely used to predict power in humans. Individual progress is often monitored on the basis of estimated power, but prediction equations are based on group data. The objective of the study was to show that vertical jump performance (VJP) and mechanical power are poorly associated, particularly within individuals. Two experiments are presented. First, 52 physically active male college students performed five maximal vertical jumps each. Second, three young male participants performed 50 maximal jumps each. Participants rested for 1 minute between jumps. VJP was calculated from kinematic data as peak body center of mass (BCOM) minus standing BCOM; peak power (PEAKPWR) was calculated from the vertical ground reaction force registered by a force plate, and average power (MEANPWR) during propulsion from the change in potential energy of BCOM. Regression analyses were performed using standardized VJP scores as the predictor variable and standardized power scores as the resulting variables, expecting an identity function of y = x (intercept = 0, slope = 1) and R2 = 1. In experiment 1, the model for zPEAKPWR R2 = 0.9707 (p < 0.0001) but slope (0.3452) ≠ 1  (p < 0.0001). The model for zMEANPWR R2 = 0.9239 (p < 0.0001); nevertheless, slope (0.4257) ≠ 1 (p < 0.0001). In experiment 2, all individual models for zPEAKPWR and zMEANPWR resulted in poor associations (R2 ≤ 0.21) and slopes ≠ 1 (p≤0.001). In conclusion, regression analysis for individuals, and even for groups, confirms that VJP is a poor predictor of mechanical power.
Dataset for experiment 2 of A novel validation approach shows new, solid reasons why vertical jump height should not be used to predict leg power
Authors: Aragón-Vargas Luis Fernando , González-Lutz María Isabel
Published: August 2023

Jump height continues to be widely used to predict power in humans. Individual progress is often monitored on the basis of estimated power, but prediction equations are based on group data. The objective of the study was to show that vertical jump performance (VJP) and mechanical power are poorly associated, particularly within individuals. Two experiments are presented. First, 52 physically active male college students performed five maximal vertical jumps each. Second, three young male participants performed 50 maximal jumps each. Participants rested for 1 minute between jumps. VJP was calculated from kinematic data as peak body center of mass (BCOM) minus standing BCOM; peak power (PEAKPWR) was calculated from the vertical ground reaction force registered by a force plate, and average power (MEANPWR) during propulsion from the change in potential energy of BCOM. Regression analyses were performed using standardized VJP scores as the predictor variable and standardized power scores as the resulting variables, expecting an identity function of y = x (intercept = 0, slope = 1) and R2 = 1. In experiment 1, the model for zPEAKPWR R2 = 0.9707 (p < 0.0001) but slope (0.3452) ≠ 1  (p < 0.0001). The model for zMEANPWR R2 = 0.9239 (p < 0.0001); nevertheless, slope (0.4257) ≠ 1 (p < 0.0001). In experiment 2, all individual models for zPEAKPWR and zMEANPWR resulted in poor associations (R2 ≤ 0.21) and slopes ≠ 1 (p≤0.001). In conclusion, regression analysis for individuals, and even for groups, confirms that VJP is a poor predictor of mechanical power.
Optimerad fysisk vårdmiljö på akutmottagning: ur patienters, närståendes och personals perspektiv
Authors:   ,   Linnaeus University, Faculty of Health and Life Sciences, Department of Health and Caring Sciences, Lindahl Jeanette
Published: August 2023

Aim: This dissertation called the COPE (Caring Optimized Physical Environment) project, aimed to evaluate the perceptions of patients, family members, and staff regarding support from the physical environment, with a focus on light, color, and person-centered climate, before and after there furbishment and remodeling of an emergency department (ED). Methods: A quasi-experimental design was employed, implementing evidence-based design principles for light and color in the ED. The study evaluated the perceived support and person-centered climate among participants using a newly developed and validated questionnaire, the Light and Color Questionnaire (LCQ). It also validated a Swedish version of the Person-centered Climate Questionnaire for family members (PCQ-F). A total of 600 participants, including patients, family members, and staff, were included in the study. Results: The scores for the perceptions of light and color and person centered climate were higher after the redesign than before for patients, family members, and staff. Thus, redesign of a healthcare environment based on knowledge and experience in light and color design corresponded with a positive change in self rated perceived support of that environment to all three groups: patients, family members, and staff. The redesign involved enhancing access to natural daylight by incorporating additional windows and diverse artificial lighting options. The redesign also included the use of color coding to facilitate way finding and uniform colors for shared floor surfaces and contrasting colors for non-patient areas to enhance safety. Conclusion: The intervention, which focused on optimizing lighting and color in the ED, coincided with an increased perceived support from light and color for patients, family members, and staff. Further, the changes in light and color, along with the overall redesign, concurred with a higher score for perceived person-centered climate. These findings emphasize the importance of evidence-based design interventions and highlight the potential benefits they can bring to staff and patients in other health care settings.
Argumentos epistémicos de la superación profesional del jefe de cátedra de educación física
Authors: Ferrat Peláez Juan , Maestre Cabrales Dayroandis , Ortiz Guerra Juan Guillermo
Published: August 2023

El presente artículo tiene como objetivo compilar los principales fundamentos epistémicos relacionados con la superación profesional del jefe de cátedra de Educación Física, desde la perspectiva filosófica, pedagógica, psicológica y sociológica. A partir de los métodos empleados se realiza una sistematización teórica donde se exponen los aspectos más relevantes de cada uno de estos fundamentos que sustentan este proceso así como algunos elementos esenciales que permiten fundamentar la estrategia para la superación profesional de estos directivos en función de mejorar su desempeño profesional en el combinado deportivo y el impacto que tiene esta en la autotransformación de este, los docentes pertenecientes a su claustro, y a su vez, en la transformación de la sociedad.
To Building a Single Economic Space of Russia: Current Accents of the “Coherence” Category
Authors:   Financial University Under the Government of the Russian Federation, Makar Svetlana , Stroev Pavel ,   Financial University Under the Government of the Russian Federation
Published: August 2023

Based on the rather well-known features of Russia, size, physical-geographical and economic-geographical position of the territory, the task of organizing business activity in the country, both at the national and subnational levels, remains constantly relevant. The interactions that developed during the Soviet period in the development of the state, which included Russia, have largely lost their significance by now. For modern actors of business activity in the time being, the difficulties of interaction are obvious, the reason for which is a significant spatial differentiation and polarization of the economic space. In this respect, the article analyzes scientific ideas regarding the category of “coherence”, presented in modern economic studies of the last three decades, during which there was a decrease in the coherence of the economic space of Russia, which in the time being began to act as an acting factor restraining economic growth at the national and subnational (regional) levels. The modern idea of coherence is inseparable from such categories as “economic space” and “interaction.” The authors identified a number of significant concepts associated with the key category of “coherence.” The dynamics in the content saturation of this category are revealed, which can be interpreted as a continuous process of updating development priorities and the need for new emphasis in understanding this category. The multidimensional nature of the application of the “coherence” category requires specification of its subject area to clarify additional characteristics of coherence. With the focus on the economic space coherence, we note the significance of such an indicator as the intensity of interactions between spatial structures that receive the status of “centers” that influence the maintenance and development of their environment. Clarifications in the interpretation of the concept of “coherence” are closely related to its quantitative assessment. Differences in the concept of “coherence” in domestic and foreign studies are revealed.
Development of Methodological Tools for Assessing the Effectiveness of Clusters in the Russian Federation
Authors:   Astrakhan State University, Tomashevskaya Yulia
Published: August 2023

The article suggests the author’s version of the approach to assessing the effectiveness of clusters existing in the territory of the Russian Federation. The methodological tools are focused on assessing the effectiveness of industrial clusters, included in the register of the Ministry of Industry and Trade of the Russian Federation, and sectoral territorial and industrial clusters, supervised by the subjects of the Russian Federation. They are differentiated and include three evaluation criteria for each type of cluster. The evaluation system was tested on the example of 191 clusters. Information was collected through GISP and EMISS systems, sites-aggregators of data on companies, telephone interviews with public authorities responsible for the implementation of cluster policy in the regions, official response letters from ministries and cluster development centers in Russia. The work also proposed a system for assessing the performance of industrial clusters, supervised by the Ministry of Industry and Trade of the Russian Federation. The results made it possible to identify clusters with high and low levels of efficiency and effectiveness. This approach can be used by state authorities as part of the process of monitoring the activities of clusters and the implementation of cluster policy in order to optimize funding and improve the effectiveness of their support activities.
Energy Saving and Energy Efficiency Improvement: Balance of State Supervision and Self-Regulation
Authors:   Volzhsky Institute of Economics, Pedagogy and Law, Skokov Roman , Pribytkov Yuri ,   Volzhsky Institute of Economics, Pedagogy and Law
Published: August 2023

The article presents an analysis of the theory and practice of state regulation and market selfregulation in the field of energy saving and energy efficiency improvement, their evolution and balance changes, the periodization of the development of domestic legislation and control, analysis of the practice of implementing control and supervisory measures in Russia and the Volgograd region. The current trend in the field of energy saving and energy efficiency improvement is characterized by a shift in priority from state supervision and administrative regulation to digital monitoring and market self-regulation, in which appropriate measures can achieve the set goals faster and at a lower cost. The coverage of the self-regulation processes of the entire business community, rather than its individual representatives, will not only ensure more reliable and high-quality fulfillment of contractual obligations but also increase the competitiveness of the domestic energy sector as a whole. The tasks of self-regulatory organizations in the energy sector may include participation in the development of a regulatory framework, information support, consulting in the field of personnel training, and voluntary agreements in the field of ecodesign. It is revealed that in Russia and the EAEU countries, there is a significant potential for energy saving and energy efficiency improvement through the formation and development of a largely self-regulating ecodesign system for energy-consuming goods.
Options on Interbank Rates and Implied Disaster Risk
Authors: Doshi Hitesh , Kim Hyung Joo , Seo Sang Byung
Published: August 2023

The identification of disaster risk has remained a significant challenge due to the rarity of macroeconomic disasters. We show that the interbank market can help characterize the time variation in disaster risk. We propose a risk-based model in which macroeconomic disasters are likely to coincide with interbank market failure. Using interbank rates and their options, we estimate our model via MLE and filter out the short-run and long-run components of disaster risk. Our estimation results are independent of the stock market and serve as an external validity test of rare disaster models, which are typically calibrated to match stock moments.
CLEC11A expression as a prognostic biomarker in correlation to immune cells of gastric cancer
Authors: Fang Weidan , Wan Dewen , Yu Yi , Zhang Ling
Published: August 2023

Gastric cancer (GC) is a prevalent malignant cancer characterized by a poor survival rate. The C-type lectin domain family 11 member A (CLEC11A) is part of the C-type lectin superfamily, and its dysregulation has been implicated in the progression of several cancers. The specific role of CLEC11A and its association with immune infiltration in GC, however, remains unclear. In this study, we employed The Cancer Genome Atlas (TCGA) database, Gene Expression Omnibus (GEO) database, Tumor IMmune Estimation Resource (TIMER) database, Gene Expression Profiling Interactive Analysis (GEPIA), UALCAN, Kaplan–Meier plotter databases, gene ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), Gene Set Enrichment Analysis (GSEA), and the CIBERSORT algorithm to investigate CLEC11A expression, its prognostic significance, its association with tumor immune infiltration, and gene function enrichment in GC. We conducted western blotting, Cell Counting Kit-8 (CCK-8), wound healing, and transwell assays to validate CLEC11A's function. We found that CLEC11A expression was significantly elevated in GC when compared to adjacent non-tumor tissues. Elevated CLEC11A expression was strongly associated with poor survival outcomes and advanced clinicopathological stages.  Moreover, heightened CLEC11A expression positively correlated with immunomodulators, chemokines, and the infiltration of immune cells, especially M2 macrophages, in GC. Additionally, CLEC11A silencing suppressed GC cells proliferation, migration and invasion in vitro. Our results elucidate the functions of CLEC11A in GC, suggesting its potential as a valuable prognostic biomarker and therapeutic target for GC immunotherapy.
THE EFFECT OF PHASE CHANGE MATERIALS ON ROOM TEMPERATURE FOR WINTER AND SUMMER
Authors: SOĞUKPINAR Hacı , BOZKURT İsmail
Published: August 2023

The efficient use of our existing energy resources is as important as finding new energy sources, since the demand for energy is increasing day by day. Heating and cooling loads in buildings constitute a large part of energy consumption. Therefore, it is very important to improve the energy performance of buildings. The utilization of phase change materials to increase the energy efficiency of buildings is one of the recent research topics. In this study, the effect of phase change materials on room temperature for winter and summer months was investigated numerically by defining real environmental conditions in the virtual environment. Phase change material with thermophysical properties suitable for Mediterranean climate conditions was selected for summer and winter. It can keep the room temperature at a slightly lower level during the daytime in summer and the room temperature higher in winter than in the insulated state case. As a result, phase change materials can be used as a natural air conditioner in the summer, as well as a natural heater at night in the winter. On the other hand, smart bricks can be produced that can absorb the heat transmitted from the inside to the outside by using different phase-change materials.
U54 SCENT Normal Lung Donor Tissue Collection Procedure v1
Authors: Hartwig Matthew
Published: August 2023

This document outlines the acceptance criteria and workflow for notification, screening, acceptance and logistics of donor lung collection between Duke University Medical Center and our local Organ Procurement Organizations. Donor Lungs accepted for the SCENT protocol arrive to our Surgery Substrate Services Core packaged on ice, en bloc and are processed and banked by a Duke Histologist.
U54 SCENT Normal Lung Autopsy Tissue Collection Procedure v1
Authors: Glass Carolyn
Published: August 2023

This document outlines the required criteria and collection protocol for normal lung specimen acquisition from autopsy at Duke University Hospital through the Biorepository and Precision Pathology Center (BRPC) in the Department of Pathology.
U54 SCENTTranscription Factor (TF)-Phosflow Flow Cytometry Panel v1
Authors: R Healy Zachary
Published: August 2023

This flow cytometry panel was developed for simultaneous quantification of transcription factors, phosphorylated kinases, and endosomal β-galactosidase activity in human peripheral blood mononuclear cell (PBMC) subsets including T cells, B-cells, NK cells, and monocytes. This protocol begins immediately following cell thawing, counting, viability determination, and peptide stimulation. This is detailed in SENNET Antibody Staining Protocol.
Disposição de enfermeiros para o uso do telemonitoramento em usuários com condições crônicas: estudo transversal
Authors: Lino Iven Giovanna Trindade , Oliveira Raquel Gusmão de , Teston Elen Ferraz , Ferreira Patrícia Chatalov , Marquete Verônica Francisqueti , Mussi Fernanda Carneiro , Palmeira Catia Suely , Marcon Sonia Silva
Published: August 2023

Objetivo: verificar a disposição de enfermeiros da Atenção Primária em utilizar o telemonitoramento no acompanhamento de usuários com hipertensão arterial e/ou diabetes mellitus. Método: estudo transversal realizado com enfermeiros atuantes nos municípios da 15ª Regional de Saúde do Paraná. Dos 289 convidados, 65 responderam ao questionário online disponibilizado em maio e junho de 2021 no Google Forms. Foram incluídos os enfermeiros que atuavam nas unidades de saúde da 15ª Regional de Saúde e que responderam ao questionário enviado. Não foi adotado nenhum critério de exclusão, mesmo quando o enfermeiro deixava alguma questão em branco. Na análise, foram utilizados os testes Qui-quadrado, Exato de Fisher e Razão de Prevalência. Resultados: entre as variáveis analisadas, observou-se associação entre ter menos idade e menor tempo de formado e a percepção de que o telemonitoramento sem atendimento presencial é insuficiente para acompanhar os usuários, e das variáveis “telemonitoramento favorece a comunicação com o paciente” e “é possível” com “otimiza o trabalho da equipe”. E também maior disposição para uso foi observada entre os que receberam capacitação. Conclusão: ausência de capacitações e insuficiência de equipamentos e recursos humanos são fatores que afetam e podem inviabilizar o uso do telemonitoramento.
Effectiveness of Health Communication Technology on Compliance Disposition of Covid-19 Guidelines
Authors:   Department of MIS, Marketing, and Analytics, Rochester Institute of Technology, Bui Quang “Neo” , Moriuchi Emi ,   Department of MIS, Marketing, and Analytics, Rochester Institute of Technology
Published: August 2023

Recent research has mostly examined the role of health communication technology (HCT) in patient empowerment and in producing patient-focused outcomes. This study examines HCT in a larger context where it is used as a tool to improve public health. The objective is to examine how HCT is used to monitor Covid-19’s spread, and how social factors affect individual assessment of HCT and individual compliance disposition of Covid-19 guidelines. Analyzing data collected from 360 HCT users suggests that the information and system quality of HCT indeed impact users’ assessment of its effectiveness and their compliance disposition. However, such effects are strongly mediated by social factors: peer influence and government trust can sway an individual’s cognitive judgments of Covid-19 regardless of HCT’s impacts. The findings highlight the importance of social factors in pandemic management and the need to socialize health informatics to make them more effective.
Regulation as a source of Russian law: concept and types
Authors: Nazaykinskaya V. A.
Published: August 2023

The article is devoted to a special kind of normative legal acts — regulations. Due to the fact that today in Russia there is a large variety of such sources of law as regulations, there is a need not only for their classification, but also for their full study as an independent source of Russian law. The article examines the essential characteristics of the regulations, based on the analysis of the features of the regulations, which are an integral part of the Russian legal system, the author’s definition of the regulations is given. The functions performed by the regulations in the mechanism of legal regulation are indicated.The whole variety of regulations in force in Russia is divided into different groups, depending on the selected classification criteria. The classification allows us to consider the specific features of certain types of regulations, which, in turn, is extremely important for understanding the legal nature of regulations as sources of Russian law.
The effects of dual hypocretin/orexin receptor blockade on oxycodone seeking and dopamine neurotransmission in the nucleus accumbens
Authors:   , Samson Kyle , España Rodrigo A , Kortagere Sandhya
Published: August 2023

The opioid epidemic has been ongoing for decades and has impacted millions of lives. Although there are approved pharmacotherapies to treat opioid use disorder (OUD), they continue to fall short of mitigating the opioid crisis. One of the primary challenges in treating OUD is that attempted opioid-abstinence is plagued by extremely high rates of relapse. Drug craving is one of the most potent influences in driving relapse, and thus, remains an attractive target for future treatments. The underpinnings of drug craving are not completely understood, but a substantial body of work implicates dopamine in the mesolimbic pathway as being integral for drug-associated behaviors, such as drug craving. Further, the hypocretin system has recently emerged as potentially promising novel treatment for OUD, as evidence has widely supported hypocretin-based treatments in reducing motivated behaviors by way of modulating dopamine transmission. The overarching goal of this work is to investigate the state of dopamine system in the nucleus accumbens during opioid abstinence, assess how a dual hypocretin receptor antagonist, suvorexant, can reduce opioid craving, and determine if the mechanism is through normalization of aberrant dopamine transmission. To do this, rats self-administered oxycodone for 10 days under an intermittent access schedule, paired with cue-induced craving tests on abstinence day (AD) 1 and AD14, rats were sacrificed on AD2 or AD15 to measure dopamine transmission using fast-scan cyclic voltammetry. I found that rats exhibited robust persistent oxycodone seeking during abstinence and this coincided with reductions in dopamine uptake on AD2 and AD15. Next, rats underwent the same oxycodone self-administration followed by a seeking test on AD14 but were treated with vehicle or suvorexant 24 hours before the seeking test, and rats were sacrificed for FSCV on AD15. I found that suvorexant attenuated oxycodone craving behavior, with the effect being more prominent in males, and normalized dopamine uptake in the NAc. This provides additional support for the potential use of hypocretin-agents for the treatment of OUD.