bluuebunny/crossref_metadata_2025 huggingface dataset:
The Prevention of Financial Legal Risks of B2B E-commerce Supply Chain
Authors: Liu Cheng-yong , Dong Tian-yu , Meng Ling-xing
Published: January 2022

B2B supply chain finance is a new type of financial model, which is created to help companies raise funds and promote the production, operation, and development of companies in the supply chain. Based on the B2B e-commerce platform, it is used for online transactions and transactions between companies and companies. Information, integrating logistics, business flow, information flow, and capital flow for data analysis and processing. When people enjoy convenient and fast e-shopping, they must not only choose products carefully but also understand and be familiar with the relevant laws and regulations of shopping on the Internet. Avoiding potential legal risks is a key factor. The purpose of this article is to analyze the financial risks of the B2B e-commerce supply chain, according to the current Internet development trend, study the legal risks of the B2B e-commerce supply chain in the development, put forward corresponding recommendations, and build a relevant system to reduce risks. Combining some current legal issues faced by e-commerce, this article first analyzes the generation and operation mechanism of credit risk under the B2B platform online supply chain financial business model; then, based on the supply chain financial risk, a relevant system is constructed to reduce risks. This article first analyzes the generation and operation mechanism of credit risk under the online supply chain financial business model of the B2B platform; then, based on the supply chain financial risks, construct a system that can prevent and control the risks generated under this financial business model risk evaluation index system; finally, the KMV model and case are analyzed to verify whether this risk evaluation research is effective for supply chain financial risks. The experimental results show that through the KMV model, comparing the two sets of data, the default distance of most default groups is smaller than that of the normal group. It can be seen that the greater the default distance, the smaller the credit risk. When the default point coefficient is 0.85, use the KMV model which is most obvious when judging the company’s overall probability of default.
Design of a Music Recommendation Model on the Basis of Multilayer Attention Representation
Authors: Lu Wei
Published: January 2022

Current music recommendation systems can explore the general relationship between the users and songs to recommend music to the users; however, they cannot distinguish the different preferences of different users for the same song. For example, a user may like a song because of the singer, while another user will like it not for the singer but just because of the composition of the song or its melody. A recommender system that knows this difference would be more effective in recommending music to the users. To this end, this paper proposes a music recommendation model based on multilayer attention representation, which learns song representations from multidimensions using user-attribute information and song content information, and mines the preference relationship between users and songs. In order to distinguish the differences in user preferences for multidomain features of songs, a feature-dependent attention network is designed; in order to distinguish the differences in user preferences for different historical behaviors and to explore the temporal dependence of user behaviors, a song-dependent attention network is designed. Finally, the SoftMax function is used to calculate the distribution of users’ preferences for candidate songs and is used to generate recommendations. The experimental results on 30Music and MIGU datasets show that the proposed model achieves significant improvement in recall and MRR compared with the current recommendation models.
Similarities and Differences between COVID-19-Associated Nephropathy and HIV-Associated Nephropathy
Authors: Chen Anqun , Yin Lijun , Lee Kyung , He John Cijiang
Published: January 2022

Kidney disease is a major complication of viral infection, which can cause both acute and chronic kidney diseases via different mechanisms such as immune-mediated injury, kidney cell injury from a direct viral infection, systemic effects, and antiviral drug-induced nephrotoxicity. HIV-associated nephropathy (HIVAN), characterized by collapsing focal segmental glomerulosclerosis (cFSGS), has been described 2 decades ago as a major complication of acquired-immunodeficiency syndrome. The pathogenesis of HIVAN has been well studied, including viral entry, host response, and genetic factors. The incidence of this disease has been dramatically dropped with current antiretroviral therapy. In the recent severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic, acute kidney injury was also found to be a major complication in patients with (coronavirus disease) COVID-19. These patients also developed glomerular disease such as cFSGS in African Americans with apolipoprotein L1 risk alleles, similar to HIVAN. Whether SARS-CoV-2 can infect kidney cells locally remains controversial, but both local infection and systemic effects are likely involved in the pathogenesis of this disease. In this review, we present a comparison of the clinical presentations, pathological findings, disease mechanisms, and potential treatments between HIVAN and COVID-19. Leveraging the knowledge in HIVAN and experimental approaches used to study HIVAN will facilitate the exploration in the pathogenesis of COVID-19-associated kidney disease and improve our management of COVID-19 patients.
Prácticas espaciales de infancias en edificio de gran altura y densidad habitacional
Authors: Reyes-Bahamondes Julián , Cornejo Díaz Diana
Published: January 2022

(analytical)The objective of this article is to analyze the spatial practices and representations of children living in a high-rise building in the center of the Chilean capital. With a qualitative, critical-ethnographic design and a collaborative model, 5 children from 10 to 13 years old and 6 adults from 25 to 55 years old, of different nationalities and residence times, participated in both studies. The content analysis found that the physical composition and relational dynamics in the building have severely restricted the possibilities of spatial deployment of children residing in the building, contributing to their historical invisibility and confinement. In spite of this, practices of resistance and re-signification of space were found on the part of the children, who create community in an urban framework that does not favor it.
Keywords: Childhood; urban space; building; ethnography; population density; urban planning.
Water Conflicts and Hydrocracy in the Americas. Coalitions, Networks, Policies
Authors: Mercier Delphine ,   Instituto Nacional Francês de Pesquisa Científica, Massardier Gilles ,   Centro de Cooperação Internacional em Pesquisa Agronômica para o Desenvolvimento, Jacobi Pedro Roberto ,   Universidade de São Paulo. Instituto de Energia e Meio Ambiente
Published: January 2022

This book develops an international comparative approach to water conflicts in several American cities (USA, Mexico, Brazil, Peru, Bolivia). Struggles for water can be related to different issues: increase in water prices, installation of water catchment systems, negotiations of commissioning contracts, promotion of municipal plans for water delivery, etc. Such conflicts tend to structure coalitions which, in turn, influence policy-making; they impact local orders that are embedded at multiple levels of social practices; they involve most of the environmental and political institutions of a city or a country. In order to understand how these hydrocracies work, this book proposes a new framework of analysis taking into account the beliefs of the protagonists of the conflicts, their positions in the policy networks and their social characteristics.
Nós da linha de frente: diálogos sobre o ser da saúde no contexto da pandemia
Authors: Therense Munique , Perdomo Selma Barboza , Fernandes Ariane Cristiny da Silva
Published: January 2022

O objetivo deste estudo é compartilhar os fazeres e os saberes de profissionais da área da saúde que atuam na linha de frente no enfrentamento da pandemia por Covid-19 em diferentes regiões do Brasil, com base na discussão sobre suas concepções em relação à finitude, sobre os caminhos e as estratégias adotados e/ou necessários para a promoção de sua saúde mental no período da pandemia e sobre a construção de memórias afetivas e/ou traumáticas de suas ações, condutas e desafios enfrentados na linha de frente. O método utilizado foi a criação de um espaço virtual para discussões teóricas, troca de vivências e promoção da saúde mental, que aconteceram em quatro momentos, uma vez por semana, no mês de julho de 2020. As narrativas dos profissionais sinalizaram as dificuldades e os aprendizados relativos ao confronto exaustivo com a morte, bem como as estratégias funcionais e disfuncionais adotadas para fazer frente aos problemas e para a manutenção da saúde mental. Concluiu-se que experimentar o protagonismo de construir coletiva e eticamente uma narrativa sobre as experiências da pandemia mostrou-se dispositivo de cuidado e refazimento importantes para os participantes da ação.
Introduction: Jesuits in Asian-Pacific Borderlands
Authors: Coello de la Rosa Alexandre
Published: January 2022

In the last years, a growing number of scholars of world history have focused on Jesuit networks, economic and cultural interactions in the Asian-Pacific territories. This introduction and the essays contained within the pages of this special issue bring religious mobility to the foreground, putting special emphasis on the way how “conversion” (both religious and cultural) transformed the trans-Pacific frontier into a zone of sustained contact and transculturation involving Europe, Asia, and the Americas. First, it explores contending networks of evangelization, which revolve around a basic premise: they were heterogeneous and uncoordinated, moving in unexpected and complex directions. Second, it analyzes the way in which Jesuit evangelization effected a “tricultural convergence” of Asian, Iberian, and indigenous cultures towards the production of a “global consciousness.” Finally, it examines a meta-history of Iberian globalization and empire, which emphasized a failed hegemony over Islamic territories of southern Philippines as much as diminished the native Filipino as historical subject.
Pelargonium pseudosetulosum (Geraniaceae), a new species in sect. Pelargonium from the Kogelberg-Kleinmond area in Western Cape Province, South Africa
Authors: LE ROUX M. MARIANNE , MANNING JOHN C.
Published: January 2022

Populations of plants from around Kleinmond in the Western Cape Province (South Africa), previously identified as Pelargonium setulosum, differ from typical populations of that species in ecology, distribution, and morphologically in the shape of the nectar guides, and appear to constitute a separate species. Field work was done, specimens were collected in the field, and material from four different herbaria were studied to record morphological variation. The Kleinmond populations previously included in P. setulosum are described as the new species P. pseudosetulosum. Morphological, ecological, and geographical evidence indicate that this species forms part of Pelargonium subg. Pelargonium sect. Pelargonium.
Targeted Delivery of Glypican 3 (GPC3) Antibody-Modified MicroRNA (miR let-7b-5p) Polymer Nanoparticles to Sorafenib-Resistant Hepatsocellular Carcinoma Cells
Authors: Zhou Shuping , Ma Yongfang , Liu Xueke , Yu Pan , Huang Ning , Song Li , Xu Ruyue , Huo Zhen , Zhu Tao , Tang Xiaolong
Published: January 2022

The miR let-7b-5p (a kind of microRNAs) has many pathophysiological regulation effects, including human hepatocellular carcinoma (HCC) pathogenesis. This study investigated whether nanoparticle-mediated miR let-7b-5p could jointly enhance the therapeutic effect of sorafenib on HCC by
inhibiting the proliferation of HCC cells, inducing apoptosis, and reversing drug resistance. We evaluated the level of miR let-7b-5p in sorafenib-resistant HepG2 cells (HepG2R) and HepG2 HCC cells by qRT-PCR and analyzed the biological effects of hepatocellular carcinoma treated
with sorafenib with miR let-7b-5p, and further studied the toxicity of nanoparticles (Ab-miR-NPs) that deliver miR let-7b-5p mimics and target GPC3 on the surface of hepatocellular carcinoma cells. Results showed that, in HepG2 cells, the expression level of miR let-7b-5p was significantly
higher than that in HepG2R cells. Targeted nanoparticle Ab-miR-NPs mediated the delivery of miR let-7b-5p to the HCC cytoplasm and released miRNA after being broken down, down-regulating the expression of IGF1R and inhibiting AKT/mTOR and Ras/Raf signal transmission. Ab-miR-NPs
not only enhanced the proliferation of sorafenib in cultured HepG2R cells and induced cell apoptosis efficiency, but they also improved the anti-tumor activity in the mouse models. These results indicated that GPC3 antibody-modified PLGA-PLL (polylactic acid-glycolic acetic copolymer
grafted hyper-branched polylysine) loaded miR let-7b-5p polymer nanoparticles combined with sorafenib may be a new treatment strategy for HCC resistant to sorafenib.
Survival Predictors of Resectable Gallbladder Carcinoma: An Analysis of the Surveillance, Epidemiology, and End Results Database
Authors: Zhu Jisheng , Wu Yunxiang , Xiao Weidong , Li Yong
Published: January 2022

Background

To analyze population-level data for resectable gallbladder carcinoma (GBC) according to the eighth edition of the American Joint Committee on Cancer staging system.

Methods

We queried the Surveillance, Epidemiology, and End Results database to identify all patients aged 18 years or older with T1-3 M0 GBC diagnosed between 2004 and 2015. Multivariate cox hazard regression analysis was used to identify prognostic factors of cancer-specific survival (CSS).

Results

Of the 1601 eligible patients, 1310 (81.8%) underwent cholecystectomy only and 291 (18.2%) underwent an en bloc resection. Overall, 219 (13.7%) patients were in stage I, 400 (25%) were in stage II, 260 (16.2%) were in stage IIIA, 653 (40.8%) were in stage IIIB, and 69 (4.3%) were in stage IVB. The 5-year survival rates for patients were 82.7% for stage I, 73.4% for stage II, 31.9% for stage IIIA, 24.1% for stage IIIB, and 10% for stage IVB. Multivariate cox analysis indicated that predictors of decreased CSS included age at diagnosis >65 years, tumor size >3.2 cm, adenocarcinoma, increasing tumor spread, and lymph node involvement. Besides, chemotherapy and radiation were predictors of increased CSS.

Conclusions

Older age, increasing tumor size, adenocarcinoma, and advanced tumor/node stage were associated with a poorer prognosis after resection for GBC. Furthermore, patients with resectable GBC can benefit from adjuvant therapy.
Staying Out of Trouble: Criminal Cases Against Russian Mayors
Authors: Buckley Noah , Reuter Ora John. , Rochlitz Michael , Aisin Anton
Published: January 2022

Although repression against elites is a common occurrence in authoritarian regimes, we know little about which elites are targeted. This paper uses an original dataset on the prosecution of mayors in large Russian cities to examine the factors that make elites more likely to be arrested. We argue that in electoral authoritarian regimes like Russia, regime leaders are reluctant to arrest popular officials. Such officials command political capital that is useful to the regime, and arrests of prominent officials can produce popular backlash. We examine this argument using an original dataset on all arrests of municipal leaders in Russia’s 221 largest cities between 2002 and 2018. We find that mayors who won their elections by large margins are less likely to be arrested. In addition, we document several other substantively important patterns: (1) a mayor’s professional background is not related to the likelihood of arrest, (2) opposition mayors are four times more likely to be arrested, and (3) mobilization of votes for the regime is not protective against arrest.

JEL Classifications P16, P30, R59
Leaders as Coaches: Towards a Code of Ethics
Authors: Milner Julia , Milner Trenton , McCarthy Grace , da Motta Veiga Serge
Published: January 2022

Building on the relational leadership model, this study investigates ethical leadership in the context of “leaders as coaches.” We used a critical incident technique to identify ethical issues that occur when leaders act as coaches in the leader-follower relationship. Findings show seven ethical issues, namely, definition ambiguity, conflict of interest, confidentiality, power imbalance, freedom to participate, boundaries and favoritism. These ethical issues take a two-edged form for leaders as coaches, given the complexity of the leader-follower relationship. The increasing prevalence of managerial coaching makes it important to pre-empt ethical issues where possible and address any that arise, in order for an organization to become or continue to be an ethical organization. A proposed code of ethics, specifically for leaders as coaches, could accompany organizational change initiatives.
Prevention Research Centers and COVID-19: Models of a Community-Engaged Response to a Public Health Emergency
Authors: Busse Kyle R. , Lemon Stephenie C. , Comerford Beth P. , Islam Nadia S. , Ulin Brigette F. , Eriksen Michael P. , Ammerman Alice S.
Published: January 2022

For more than 30 years, the network of Centers for Disease Control and Prevention (CDC)–funded Prevention Research Centers (PRCs) has worked with local communities and partners to implement and evaluate public health interventions and policies for the prevention of disease and promotion of health. The COVID-19 pandemic tested the PRC network’s ability to rapidly respond to multiple, simultaneous public health crises. On April 28, 2020, to assess the network’s engagement with activities undertaken in response to the early phase of the pandemic, PRC network leadership distributed an online survey to the directors of 34 currently or formerly funded PRCs, asking them to report their PRCs’ engagement with predetermined activities across 9 topical areas and provide case studies exemplifying that engagement. We received responses from 24 PRCs, all of which reported engagement with at least 1 of the 9 topical areas (mean, 5). The topical areas with which the greatest number of PRCs reported engagement were support of frontline agencies (21 of 24, 88%) and support of activities related to health care (21 of 24, 88%). The mean number of activities with which PRCs reported engagement was 11. The PRCs provided more than 90 case studies exemplifying their work. The results of the survey indicated that the PRCs mobilized their personnel and resources to support the COVID-19 response in less than 6 weeks. We posit that the speed of this response was due, in part, to the broad and diverse expertise of PRC personnel and long-standing partnerships between PRCs and the communities in which they work.
COVID-19 and Sickle Cell Disease–Related Deaths Reported in the United States
Authors: Payne Amanda B. , Schieve Laura A. , Abe Karon , Hulihan Mary , Hooper W. Craig , Hsu Lewis L.
Published: January 2022

Sickle cell disease (SCD) is associated with increased risk of poor health outcomes from respiratory infections, including COVID-19 illness. We used US death data to investigate changes in SCD-related mortality before and during the COVID-19 pandemic. We estimated annual age- and quarter-adjusted SCD-related mortality rates for 2014-2020. We estimated the number of excess deaths in 2020 compared with 2019 using the standardized mortality ratio (SMR). We found 1023 SCD-related deaths reported in the United States during 2020, of which 86 (8.4%) were associated with COVID-19. SCD-related deaths, both associated and not associated with COVID-19, occurred most frequently among adults aged 25-59 years. The SCD-related mortality rate changed <5% year to year from 2014 to 2019 but increased 12% in 2020; the sharpest increase was among adults aged ≥60 years. The SMR comparing 2020 with 2019 was 1.12 (95% CI, 1.06-1.19). Overall, 113 (95% CI, 54-166) excess SCD-related deaths occurred in 2020.
Back in on the Outside: Racialized Exclusion at Chicago's School/Prison Nexus and the Promise of Student Voice
Authors: Gardner Joby , Klonsky Amanda , Clemens Ishujon , Gallardo Selena , Harris Rakeisha , Rosario Natali , Suarez Ashley , Torres Bridget , Torre María Elena
Published: January 2022

Most students released from detention never return to school. This study uses youth participatory action research and Social Justice Youth Development Theory to explore the experiences of those who do. Findings demonstrate that formerly incarcerated students want to return to school but face institutionalized resistance that amounts to racialized exclusion, violence, and state-sanctioned neglect at Chicago's school/prison nexus. We offer recommendations on how to “reverse” the school-to-prison pipeline by shifting educational and youth policies from surveillance and control to care, harm reduction, and greater youth and community oversight; shifts already arising out of student and educator activism, including through YPAR.
Nodular mass—A case of auricular schwannoma
Authors: Chuang Wen-Ching , Ueng Shir-Hwa , Chuang Wen-Yu , Chan Kai-Chieh
Published: January 2022

Schwannomas are benign tumors derived from the sheath of Schwann cells. Though it is common to see schwannomas in the head and neck region, auricular schwannomas are rare and only few cases have been reported. There are no distinguishing clinical findings or images; therefore, the histopathological diagnosis is mandatory. We describe a case of auricular schwannoma with clinical pictures and discuss the differential diagnoses according to histopathologic findings.
The Effects of Charitable Giving on Life Satisfaction of Older Korean Adults: The Moderating Role of Relationship Satisfaction and Social Trust
Authors: Jun Hey Jung , Kang Miseon , Yoon Do Kyung , Lee Seol Ah , Park Hayoung
Published: January 2022

Objectives: This study investigates the effects of charitable giving on the life satisfaction of older Korean adults, examining the moderating role of relationship satisfaction and social trust, as the indicators for social capital. Methods: Nationally representative sample of individuals aged 65 to100 ( N = 8,359) from the 2019 Social Survey was used for the analyses. Results: The results from Coarsened Exact Matching and Structural Equation Modeling show that charitable giving positively affects older Korean adults’ life satisfaction. Moreover, the results of moderation analyses suggest that the effects of charitable giving on life satisfaction are stronger for those with lower levels of relationship satisfaction and social trust. Discussion: The results imply that social capital, such as relationship satisfaction or social trust, needs to be taken into consideration when exploring the effects of charitable giving in later life.
Tracheal stenting on venovenous ECMO with a dual lumen right atrium-to-pulmonary artery cannula in a COVID-19 patient with an inferior vena cava filter
Authors: Giani Marco , Pisa Andrea , Passera Eliseo , Avalli Leonello , Rona Roberto , Foti Giuseppe
Published: January 2022

A 47-year-old man, with no medical history, was diagnosed with severe COVID-19 ARDS and pulmonary embolism. Venovenous extracorporeal membrane oxygenation (ECMO) was required for impossibility to deliver protective ventilation. The patient was weaned from ECMO after clinical improvement. An inferior vena cava filter was then positioned to prevent embolization from a persistent left femoral deep venous thrombosis. Two days after the ECMO removal, a large lesion of the tracheal posterior wall was diagnosed. Tracheal stenting was deemed necessary. ECMO support was then re-established, to safely perform the bronchoscopic procedure. Due to the presence of the inferior vena cava filter, the patient was cannulated via the right internal jugular vein with a double lumen ProtekDuo cannula. The patient was then weaned from ECMO support and invasive ventilation. The tracheal stent was removed after 40 days, showing a full recovery of the tracheal lesion. The patient was discharged home in good condition.
An 8-Week Neuromuscular Training Program After Concussion Reduces 1-Year Subsequent Injury Risk: A Randomized Clinical Trial
Authors: Howell David R. , Seehusen Corrine N. , Carry Patrick M. , Walker Gregory A. , Reinking Sarah E. , Wilson Julie C.
Published: January 2022

Background:

Existing data suggest that after concussion, athletes experience an increased risk of subsequent injury. Exploring methods that may reduce injury risk after successful postconcussion return to play may lead to new treatment approaches.

Purpose:

To examine the efficacy of a neuromuscular training (NMT) intervention on acute sports-related time-loss injury over the subsequent year relative to standard of care.

Study Design:

Randomized clinical trial; Level of evidence, 1.

Methods:

A total of 27 youth athletes were assessed initially postconcussion (median, 7 days postconcussion; interquartile range [IQR], 5-10) and after return-to-play clearance (median, 40 days postconcussion; IQR, 15-52). After return-to-play clearance, they were randomly assigned to NMT intervention (n = 11; mean ± SD age, 14.7 ± 1.7 years; 36% female) or standard of care (n = 16; mean ± SD age, 15.3 ± 1.8 years; 44% female). The intervention (duration, 8 weeks; frequency, 2 times per week) included guided strength exercises with landing stabilization focus. Standard of care received no recommendations. For the subsequent year, athletes prospectively completed a monthly log of sports-related injuries and organized sports competitions.

Results:

During the first year after postconcussion return-to-play clearance, sports-related time-loss injuries were more common among standard of care relative to NMT intervention (75% [95% CI, 48%-93%] vs 36% [95% CI, 11%-69%]). After adjusting for age and sex, the hazard of subsequent injury in the standard-of-care group was 3.56 times (95% CI, 1.11-11.49; P = .0334) that of the NMT intervention group. Sports participation was similar between NMT intervention and standard of care during the year-long monitoring period (hours of organized sports per month; median, 12 [IQR, 2.6-32.1] vs 15.6 [IQR, 3.5-105.9]; P = .55). The age- and sex-adjusted incidence of injuries was 10.2 per 1000 competitive exposures (95% CI, 3.7-28.4) in the standard-of-care group as opposed to 3.4 per 1000 (95% CI, 0.9-13.4) in the NMT intervention group. After adjusting for age and sex, incidence of injuries was higher for standard of care vs NMT intervention (rate ratio, 2.96 [95% CI, 0.89-9.85]; P = .076).

Conclusion:

Although preliminary, our findings suggest that an NMT intervention initiated after return-to-play clearance may significantly reduce sports-related time-loss injuries over the subsequent year.

Registration:

NCT03917290 (ClinicalTrials.gov identifier).
Public Health Nurse-delivered Group Cognitive Behavioural Therapy for Postpartum Depression: A Randomized Controlled Trial
Authors: Van Lieshout Ryan J. , Layton Haley , Savoy Calan D. , Haber Erika , Feller Andrea , Biscaro Anne , Bieling Peter J. , Ferro Mark A.
Published: January 2022

Objectives

To examine the effectiveness of group cognitive behavioural therapy (CBT) for postpartum depression (PPD) delivered by public health nurses with little to no previous psychiatric training at improving depression, worry, social support and the mother-infant relationship.

Methods

Mothers (n = 141) living in Ontario, Canada with Edinburgh Postnatal Depression Scale Scores ≥10 and an infant <12 months of age were randomized to receive nine weekly 2-h sessions of in-person group CBT for PPD delivered by two public health nurses plus treatment as usual (TAU; experimental group) or TAU alone (control group). Primary outcomes were change in EPDS score and current major depressive disorder (Mini International Neuropsychiatric Interview) assessed immediately post-treatment (T2). Secondary outcomes included maternal worry, social support, and quality of the mother-infant relationship. All outcomes were assessed again six months post-treatment (T3).

Results

Participants in the experimental group had statistically significantly greater reductions in PPD symptoms immediately post-treatment (T2) (B = -5.35, p < 0.01), were more likely to manifest a clinically significant improvement in EPDS scores (≥4 points; OR = 3.44, 95%CI: 1.49–7.94), and no longer have symptoms consistent with current MDD (OR = 5.31, 95% CI: 1.78–15.83). Six months post-treatment (T3), experimental group participants had higher odds of clinically significant PPD improvement (OR = 5.10, 95%CI: 1.89–13.78), while 25% of the experimental group and 70% of remaining control group participants reported current MDD ( p < 0.01). Statistically significant improvements in worry and the mother-infant relationship were also observed, decreases maintained at six months post-treatment.

Conclusions

Public health nurses with little to no previous psychiatric training can be trained to deliver effective group CBT for PPD to improve depression, worry, and the mother-infant relationship. Task shifting PPD treatment with group CBT to public health nurses could improve treatment uptake and lead to better outcomes for mothers, families, and the healthcare system. (Trial Registration NCT03039530)
A review of advances in valorization and post-treatment of anaerobic digestion liquid fraction effluent
Authors: Sfetsas Themistoklis , Patsatzis Stefanos , Chioti Afroditi , Kopteropoulos Alexandros , Dimitropoulou Georgia , Tsioni Vasiliki , Kotsopoulos Thomas
Published: January 2022

Traditionally, digestate is considered a waste, which is used as fertiliser in the agriculture industry. Recent studies focus on increasing the profitability of digestate by extracting reusable nutrients to promote biogas plants cost-effectiveness, sustainable management and circular economy. This review focuses on the post-treatment and valorization of liquor which is produced by solid–liquid fractioning of digestate. Nutrient recovery and removal from liquor are possible through mechanical, physicochemical and biological procedures. The processes discussed involve complex procedures that differ in economic value, feasibility, legislative restrictions and performance. The parameters that should be considered to employ these techniques are influenced by liquor characteristics, topography, climate conditions and available resources. These are key parameters to keep in mind during designing and manufacturing a biogas plant. In the following chapters, a discussion on available liquor treatment methods takes place. The present study examines the critical aspects of the available liquor treatment methods.
Etiology, Clinical Presentation, and Outcome of Mandibular Fractures in Immature Dogs Treated with non-Invasive or Minimally Invasive Techniques
Authors: Castejón-González Ana C. , Stefanovski Darko , Reiter Alexander M.
Published: January 2022

This study was performed to report etiology, clinical presentation, and outcome of mandibular fractures in immature dogs treated with non-invasive or minimally invasive techniques. Immature dogs diagnosed with mandibular fractures from 2001 to 2016 were included in this study. Diagnosis of the mandibular fracture was achieved by oral examination and diagnostic imaging in the anesthetized dog. Twenty-nine immature dogs with 54 mandibular fractures were selected. Within the mandibular body, the regions of the developing permanent canine and first molar teeth were most commonly involved (46.4% and 35.0%, respectively). Within the mandibular ramus, 53.8% of the fractures were located in its ventral half, and 38.5% in the condylar process. Muzzling was applied in 72.4% of the dogs. All dogs had clinical healing with resolution of signs of pain and recovery of mandibular function. Mean time for clinical healing was 21 ± 9 days. Age of the dog and duration of muzzling were significantly associated with the time needed for clinical healing. In immature dogs, fractures of the mandibular body occur most commonly in the regions of the developing permanent canine and first molar teeth, while fractures of the mandibular ramus are most commonly found in its ventral half and the condylar process. Non-invasive or minimally invasive management of mandibular fractures in immature dogs carries a good prognosis regarding clinical healing and recovery of mandibular function. Dogs should be monitored for the development of dental abnormalities and/or skeletal malocclusion until permanent teeth have erupted and jaw growth is completed.
Numerical study of magnetohydrodynamic natural convection in a non-Darcian porous enclosure filled with electrically conducting helium gas
Authors: Bég O Anwar , Venkatadri K , Prasad VR , Bég TA , Leonard Henry J , Gorla RSR , Rajarajeswari P
Published: January 2022

A theoretical and computational study of MHD natural convection in an isotropic non-Darcian porous medium saturated with electrically conducting helium gas in an enclosure in the presence of heat generation is presented. A Brinkman extended Darcy-Forchheimer model is employed and the working fluid is assumed to be incompressible. The model is non-dimensionalised and converted into pressure-velocity form. The Harlow-Welch marker and cell (MAC) finite difference technique is employed to solve the nonlinear boundary value problem via pressure-vorticity coupling. A parametric investigation of the influence of Grashof number ( Gr), Hartmann magnetic number ( Ha), Darcy number ( Da), and the internal heat generation parameter ( Γ) on streamline and isotherm distributions with Prandtl number ( Pr) is 0.71 (Helium) is conducted. The variation in local Nusselt number along the left and right walls of the computational 2 D enclosure is also studied. Validation house-computational numerical MATLAB code is tests are included. Local Nusselt number is elevated at both left and right walls with greater Darcy number (higher medium permeability) and Grashof number. However, with greater internal heat generation, local Nusselt number magnitudes are enhanced at the left (cold) wall only but suppressed at the right (hot) wall. Increasing magnetic field reduces local Nusselt number at both left and right walls. With increasing magnetic field, the single vortex is strongly distorted and skewed towards the top left and lower right corners of the enclosure. Temperature contours at the left and right wall are however less intense with greater magnetic field effect. The simulations are of relevance to hybrid electromagnetic gaseous fuel cells, magnetic field control of filtration processes and porous media materials processing systems.
Influence of welding current on the microstructure, mechanical properties, residual stresses, and nano-mechanical behavior of tungsten inert gas-welded dissimilar joints of Inconel 625 and Incoloy 800
Authors: Ramay Ali Z , Shehbaz Tauheed , khan Fahd N , Junaid Massab , Iltaf Asim
Published: January 2022

In the present work, Inconel 625 and Incoloy 800 thin sheets were TIG-welded without using fillers and at three different welding currents (40 A, 50 A, and 60 A). The influence of variation in welding currents on various characteristics of the weldments was investigated using various characterization techniques. Weldments obtained at 60 A showed the highest tensile strength and plastic deformation due to the formation of cellular dendritic microstructure in the fusion zone. Observation of the fractured surfaces revealed ductile nature for all the weldments. In addition, impact tests were performed at 25°C, 150°C, and 250°C, and the results indicated that with the rise in temperature, impact toughness decreased due to coarsening of carbides at grain boundaries in all the weldments. Furthermore, impact properties and hardness of weldments were also affected owing to the differences in interdendritic spacing and grain size. Weldments obtained at 40 A depicted higher nanohardness, whereas 50 A weldment showed relatively greater pileup height as compared to other weldments. Moreover, 60 A weldments showed highest longitudinal and transverse residual stresses due to relatively higher volumetric changes.
Propulsive and combustion behavior of hydrocarbon fuels containing boron nanoparticles in a liquid rocket combustor
Authors: Jin Yushu , Xu Xu , Wang Xu , Dou Suyi , Yang Qingchun , Pan Lun
Published: January 2022

Nano-sized energetic particle as fuel additives is of great significance for liquid hydrocarbon fuels that will exhibit high-density and high-calorific value in high-speed propulsion systems. An experimental investigation has been conducted to determine the propulsive and combustion behavior of hydrocarbon fuels containing boron nanoparticles. In this study, nano-sized boron particles with average diameter of 20 nm are added into the basic fuel JP-10 and quadricyclane, respectively. They are then referred as slurry fuels and burned in the rocket combustor using pure oxygen as the oxidizer. With a wide range of excess oxidizer coefficients, three parameters characterizing the propulsion performance are employed to evaluate the effect of boron nanoparticles on hydrocarbon fuels. It is found that the boron-based slurry fuel showed superior density specific impulse. It is increased by 1.18% and 1.44% when the addition of boron particles with 10% mass fraction are added into the basic fuel JP-10 and quadricyclane, respectively. Combustion depositions of the boron-based slurry fuel located at different positions are then collected for deep analysis by means of the energy dispersive spectrometer, X-ray diffractometer, and scanning electron microscope. Comprehensive microanalysis results demonstrate that boron particles first combine with the C-element in the hydrocarbon fuel to form the boron carbide with a reticular structure, and then the boron carbide oxidizes to form block-shaped boron oxide. However, the surface boron oxide hindered the further reaction of the internal boron carbide, which limits the energy release of the boron particles and ultimately leads to the unsatisfactory combustion efficiency of the slurry fuel.
An Investigation of the Impact of Financial Literacy and Financial Socialization on Financial Satisfaction: Mediating Role of Financial Risk Attitude
Authors: Madinga Nkosivile Welcome , Maziriri Eugine Tafadzwa , Chuchu Tinashe , Magoda Zinzi
Published: January 2022

Over the years, academics have paid a lot of attention to the topic of financial literacy. As a result, the current study investigates this topic using a unique conceptual model that was created expressly to investigate the study’s claimed linkages. Three hundred eighty four people took part in the study using a web-based self-administered questionnaire. The data was analysed using Partial Least Square Structural Equation Modelling (PLS-SEM). The outcomes of this study demonstrate that those who are more willing to take chances are more likely to be content with their financial situation. Improving financial literacy and socializing has a direct impact on financial happiness. Furthermore, financial risk attitude positively facilitates the association of a customer’s monetary education and gratification associated with education. In addition, financial risk attitude positively intercedes the association of financial socialization and monetary gratification. Financial satisfaction is observed to be of paramount importance for customers, company as well as the government. The findings of this article promote the successful delivery of financial services to established target groups, followed by recommendations for the provision of financial literacy for individuals. Furthermore, the outcomes of this research have led the way for the discovery of insights potentially useful for public policy development.
The roles of intermediaries in upgrading of manufacturing clusters: Enhancing cluster absorptive capacity
Authors: Karlsen Asbjørn , Lund Henrik B , Steen Markus
Published: January 2022

Specialized clusters rely on common knowledge resources and extra-cluster linkages, but how such resources develop over time is unclear. A case in point is how extra-cluster linkages are integrated into intra-cluster networks and the role of different cluster actors in enhancing cluster absorptive capacity. The paper explores the role of cluster intermediaries in linking clusters to external knowledge sources and contributing to knowledge dissemination among cluster firms. This perspective is relevant as manufacturing firms are facing rapid changes in technology, such as those associated with ‘Industry 4.0’. Two manufacturing clusters in Norway are studied regarding cluster absorptive capacities and the role of cluster intermediaries. The authors derive two types of cluster intermediaries with different kinds of service provision well-adjusted to the firm structure. Cluster intermediaries in both cluster contexts can assist firms in tracking and adapting to rapid technological developments.
Multidisciplinary Team Care of Patients with Hemophilic Arthropathy: A Qualitative Assessment of Contemporary Practice in the UK and Canada
Authors: St-Louis Jean , Chowdary Pratima , Dolan Gerry , Goodyear Dawn , Strike Karen , Pollard Debra , Teitel Jerry
Published: January 2022

We used a structured interview to explore approaches to comprehensive hemophilia and arthropathy care among 24 healthcare professionals (HCPs) from multidisciplinary teams (MDTs) in Canada and the UK. Represented MDTs typically comprise a hematologist, nurse, physiotherapist, and sometimes an orthopedic surgeon; pediatric (and some adult) MDTs also include a social worker/psychologist. HCPs emphasized the centrality of a team approach, facilitated through MDT meetings and involvement of all MDT members in patient care. In both countries, nurses and physiotherapists play critical, multifaceted roles. Respondents agreed that MDTs are crucial for successful transitioning, which can be facilitated by close collaboration between pediatric and adult MDTs, even when they are not co-located. Physiotherapists are instrumental in providing non-pharmacological pain relief. Hematologists or physiotherapists typically make orthopedic referrals, with the nurse, physiotherapist and hematologist working together in patient preparation for (and follow-up after) surgery. MDT best practices include a non-hierarchical team approach, ensuring that all MDT members know all patients, and regular MDT meetings. Together, these real-life insights from the MDT perspective emphasize the value of the MDT approach in comprehensive hemophilia care.
Incorporation of novel therapies for the management of sickle cell disease: A pharmacist's perspective
Authors: Dela-Pena Jacqueline C. , King Madeleine A. , Brown Julia , Nachar Victoria R.
Published: January 2022

Patients with sickle cell disease (SCD) experience significant disease-related morbidity including multiorgan damage, chronic anemia, and debilitating pain crises. While hydroxyurea has been the primary disease modifying modality in SCD, novel therapies with unique mechanism of action have recently been approved. This review article examines the evidence surrounding the available SCD therapies to guide pharmacists on potential treatment selection and management strategies for patients with SCD. A systematic search of online databases was performed to identify literature on the management of SCD. While the newly approved novel agents have demonstrated clinical benefit it remains unclear how these agents fit into the treatment paradigm. Pharmacists should be aware of the data supporting the use of these novel agents to optimize use on a patient-specific basis.
Contributory factors for developing foveal neovascularization in proliferative diabetic retinopathy
Authors: Venkatesh Ramesh , Reddy Nikitha Gurram , Jayadev Chaitra , Mutalik Deepashri , Agrawal Sameeksha , Mishra Pranjal , Bhatt Abhishek , Yadav Naresh Kumar , Chhablani Jay
Published: January 2022

Purpose

Foveal neovascularisation (NV) in proliferative diabetic retinopathy (PDR) is uncommon. The study aim is to analyse a series of cases of foveal NV in PDR and ascertain the factors leading to its development.

Methods

In this retrospective case-control study, optical coherence tomography (OCT) and OCT-angiography (OCTA) images of PDR cases with/without foveal NV diagnosed on fluorescein angiography were analysed.

Results

From 124 consecutive PDR eyes, foveal NV was identified in 12 (10%) eyes. Eyes with foveal NV showed thin choroid (p = 0.001), increased FAZ area and reduced vessel density at the macula compared to control group on OCT and OCTA. After regression analysis, an increased FAZ in the superficial capillary plexus slab (p = 0.002) was associated with foveal NV development.

Conclusion

Our case series suggest that foveal NV is an uncommon finding, occurring due to reduced choroidal and inner retinal perfusion at the macula. Further studies are required to assess the treatment outcomes in such eyes.
Effects of the @ctivehip telerehabilitation program on the quality of life, psychological factors and fitness level of patients with hip fracture
Authors: Mora-Traverso Marta , Prieto-Moreno Rafael , Molina-Garcia Pablo , Salas-Fariña Zeus , Martín-Martín Lydia , Martín-Matillas Miguel , Ariza-Vega Patrocinio
Published: January 2022

Introduction

Telerehabilitation has emerged in the last decade as a promising alternative to conduct the rehabilitation process at home. However, there are no studies testing the effects of telerehabilitation interventions for patients with hip fracture on quality of life nor psychological factors, whereas the evidence on fitness level is scarce. Thus, the aim of this study is to test the effects of the @ctivehip telerehabilitation program on the quality of life, psychological factors and fitness level of patients who had suffered a hip fracture.

Methods

The present study is a non-randomized clinical trial that includes patients older than 65 years old with a hip fracture and their family caregivers (ClinicalTrials.gov; Identifier: NCT02968589). Per-protocol (64 participants) and intention-to-treat (71 participants) analyses were performed, the first being the main analysis. The intervention group received a home-based multidisciplinary telerehabilitation intervention, called @ctivehip, that lasted 12 weeks. The control group received the traditional care and rehabilitation provided by the Andalusian Public Health Care System. The outcomes measured were the patients’ quality of life through the EuroQol Quality of Life Questionnaire (EQ-5D), physiological factors (anxiety and depression) using the Hospital Anxiety and Depression Scale (HADS) and the fitness level, assessed with the International Fitness Scale.

Results

The quality of life of the telerehabilitation group increased, while the control group scored worsened at the 3-month follow-up (medium effect size: 0.66 SDs; p  =  0.006). The telerehabilitation group demonstrated a greater decrease than the control group in the total HADS score (medium effect size: −0.50 SDs; p  =  0.015). Lastly, the telerehabilitation group recovered a fitness level close to the pre-hip fracture in comparison with the control group (small effect size: 0.49 SDs; p  =  0.022).

Discussion

The @ctivehip telerehabilitation program seems to be a promising treatment to improve the quality of life and psychological factors (i.e. anxiety and depression) of older adults after a hip fracture, as well as to recover their previous fitness level.