bluuebunny/crossref_metadata_2025 huggingface dataset:
A Graph-based Approach to Person Name Disambiguation in Web
Authors: Emami Hojjat
Published: May 2019

This article presents a name disambiguation approach to resolve ambiguities between person names and group web pages according to the individuals they refer to. The proposed approach exploits two important sources of entity-centric semantic information extracted from web pages, including personal attributes and social relationships. It takes as input the web pages that are results for a person name search. The web pages are analyzed to extract personal attributes and social relationships. The personal attributes and social relationships are mapped into an undirected weighted graph, called attribute-relationship graph. A graph-based clustering algorithm is proposed to group the nodes representing the web pages, each of which refers to a person entity. The outcome is a set of clusters such that the web pages within each cluster refer to the same person. We show the effectiveness of our approach by evaluating it on large-scale datasets WePS-1, WePS-2, and WePS-3. Experimental results are encouraging and show that the proposed method clearly outperforms several baseline methods and also its counterparts.
Graph Queries
Authors: Bonifati Angela , Dumbrava Stefania
Published: May 2019

We review various graph query language fragments that are both theoretically tractable and practically relevant. We focus on the most expressive one that retains these properties and use it as a stepping stone to examine the underpinnings of graph query evaluation along graph view maintenance. Further broadening the scope of the discussion, we then consider alternative processing techniques for graph queries, based on graph summarization and path query learning. We conclude by pinpointing the open research directions in this emerging area.
Andrew Chien Speaks Out on the Impact of Current Trends in Architecture
Authors: Winslett Marianne , Braganholo Vanessa
Published: May 2019

Welcome to ACM SIGMOD Records series of interviews with distinguished members of the database community. I'm Marianne Winslett, and today, we're at the 2017 SIGMOD and PODS Conference in Chicago. I have here with me Andrew Chien who's a professor at the University of Chicago. Andrew is an ACM fellow, an IEEE fellow, and a fellow of the American Association for the Advancement of Science. Before joining Chicago, Andrew spent five years as the vice president/director of Intel Research. Andrew's Ph.D. is from MIT.
Data Management Systems Research at TU Berlin
Authors: Abedjan Ziawasch , Breß Sebastian , Markl Volker , Rabl Tilmann , Soto Juan
Published: May 2019

Data management systems research at TU Berlin is spearheaded by the Database Systems and Information Management (DIMA) Group, the Big Data Management (Big- DaMa) Group, as well as the affiliated Intelligent Analytics for Massive Data (IAM) Research Group at the German Research Center for Artificial Intelligence (DFKI). Jointly, our research activities encompass a wide variety of database topics, including benchmarking, data integration, modern hardware, and scalable data processing.

As of Fall 2018, the current team is comprised of three university professors, thirteen senior and postdoc researchers, twenty PhD students, and several research assistants. Among our notable accomplishments is the DFG-funded Stratosphere Research Unit, which laid the groundwork for what would later become Apache Flink. DIMA has also been leading the Berlin Big Data Center, one of only two BMBF-funded Big Data Competence Centers in Germany since 2014. In addition, DIMA is co-directing the Berlin Center for Machine Learning, one of four BMBF-funded Machine Learning Competence Centers in Germany.
Productivity Measurement: Racing to Keep Up
Authors: Sichel Daniel E.
Published: May 2019

This article provides a nontechnical review of the literature and issues related to the measurement of aggregate productivity. I begin with a discussion of productivity measures, their performance in recent decades, and key measurement puzzles that emerge from the data. The remainder of the review focuses on two important questions. First, how do we make more accurate the measures of prices used to deflate nominal output so as to win (or at least not lose) the race for economic measurement to keep up with a changing economy? I frame the issues and point to the most important and promising areas for further research. Second, what does or should GDP measure? I defend GDP as a valuable measure of production and offer suggestions for improving it. At the same time, I emphasize the importance of measuring economic welfare (well-being) and argue that GDP should be supplemented with a satellite account that measures economic welfare.
Dielectric Characteristics Analysis of Aluminum Electrolytic Capacitor Based on Linear Response Funcation_Slide_235th ECS
Authors: Mukaiyama Daisaku
Published: May 2019

We discuss the dielectric characteristics of Aluminum Electrolytic Capacitors based on linear response theory. Furthermore, a useful formula had been derived to analyze the dielectric properties of Aluminum oxide layer in Aluminum Electrolytic Capacitors. #ECS 235,Tuesday, 28 May 2019, 10:00 - 12:00,Dallas Sheraton Hotel - Pearl , Abstract Number : #F03-1106.
TIM-3 and TIM-1 Could Regulate DecidualγδTCR Bright T Cells during Murine Pregnancy
Authors: Nörenberg Jasper , Meggyes Matyas , Jakso Pal , Miko Eva , Barakonyi Aliz
Published: May 2019

Pregnancy is an immunological enigma where paternal antigens are present at the fetomaternal interface. What regulates the local immunotolerance, which is necessary to prevent rejection of the conceptus, is still under strong investigation. Gamma/delta T cells are believed to play a role in the local regulation of this immunotolerance towards the semiallogenic fetus. Gamma/delta T cells from the uterus and spleen of pregnant and nonpregnant mice were analyzed by flow cytometry. We confirmed that the rate ofγδT cells in the decidua increases during murine pregnancy and half of decidualγδT cells are CD4+. Furthermore, we found a unique association of CD4 or CD8 coreceptor expression with theirγδTCR intensity, where in all investigated groups CD4- or CD8-positiveγδT cells seemed principally to beγδTCRdim. In addition, compared to peripheralγδT lymphocytes, a greater proportion of decidualγδT cells expressed the cytotoxic marker CD107a and markers of Th1 or Th2 polarization (TIM-3, TIM-1), where decidualγδTCRbright cells were characterized by high TIM-3 and TIM-1 receptor expression. On the other hand, no difference in the expression of CD160, a receptor with dual function affecting cytotoxicity and T cell inhibition, was detected. Within lymphocytes expressing CD107a, TIM-1, or CD160, the rate ofγδT cells was significantly higher in the decidua. According to our results, cytotoxic potential of decidualγδTCRbright cells could be regulated by TIM-3 ligation, while the TIM-1 receptor seems to be able to influence the Th1-Th2 balance at the fetomaternal interface. These mechanisms could play a part in the active maternal immunotolerance towards the fetus, allowing an efficient protection against pathogens during healthy murine pregnancy.
Atypical Presentation of Atraumatic Spinal Subdural Hematoma Associated with Warfarin: A Case Report and Review of the Literature
Authors: Arain Abdul Rehman , Moral Muhammad , Shams Saadia , Desai Khusboo , Kalsa Khunwar
Published: May 2019

Nontraumatic spinal subdural hematomas secondary to anticoagulants are remarkably rare. A case of spontaneous, atraumatic subdural hematoma involving the thoracic region in an 80-year-old woman on warfarin is reported. The patient presented with gross motor and sensory loss, delayed onset of incontinence, and no other symptoms. An MRI suggested an epidural hematoma concentrated around the T4-T9 levels. She was taken emergently to the OR approximately 30 hours after the initial onset of symptoms for a T3-T11 laminectomy. No epidural hematoma was noted. However, discoloration and bulging of the thecal sac were noted, and the dura was incised longitudinally from T2 to T10 revealing an expansive jelly-like blood clot which was evacuated. Postoperatively, the patient had regained 1/2 sensory function in the bilateral lower extremities. At the 2-week mark, the patient was still incontinent and showed 2/2 sensory and 2/5 motor functions in select muscle groups in her bilateral lower extremities. Completely nontraumatic, spontaneous subdural hematomas of the spine are very rare, and early surgical decompression within 24 hours from symptom onset may allow neurological recovery. Large extensive laminectomies up to 10 thoracic levels have been shown to be safe and effective in a few cases, including our case.
Evaluation of the Candida sp. 99-125 Lipase Positional Selectivity for 1,3-Diolein Synthesis
Authors: Bi Yanhong , Duan Zhangqun , Zhang Wenjing , Xu Lei , Wang Zhaoyu , Zhao Xiaojuan , Zhao Xiangjie , Yang Jiali
Published: May 2019

In this study, comparative experiments were carried out to investigate the positional selectivity of Candida sp. 99–125 lipase in preparing 1,3-diolein by using medium engineering strategy. The results indicated that the diolein yield was markedly enhanced from 56.5% to 86.7% with increasing log⁡P values of the solvents, while the selectivity of the examined lipase for the sn-1 over the sn-2 hydroxyl of glycerol was decreased, thus leading to a reduced 1,3-diolein to 1,2-diolein ratio. To evaluate the possibility of industrial enzymatic production of 1,3-diolein, larger-scale experiments were assessed. After being used repeatedly for eight batches, the diolein content reached 95.1%, while the 1,3-diolein to 1,2-diolein ratio was 7:1 following purification. Results of the kg level experiments significantly demonstrated the practicability of the enzymatic process and the efficiency of the purification strategy for the product.
Broadcasting Directional Modulation Based on Random Frequency Diverse Array
Authors: Xie Jian , Qiu Bin , Wang Qiuping , Qu Jiaqing
Published: May 2019

Frequency diverse array- (FDA-) based directional modulation (DM) is a promising technique for physical layer security, due to its angle-range dependent transmit beampattern. However, the existing schemes are not suitable for the broadcasting scenario, where there are multiple legitimate users (LUs) to receive the confidential message. In this paper, we propose a novel random frequency diverse array- (RFDA-) based DM scheme to realize the point to multi-point broadcasting secure transmission in both angle and range dimension. In the first stage, the beamforming vector is designed to maximize the artificial noise (AN) power, while satisfying the power requirement of LUs for transmitting the confidential message simultaneously. In the second stage, the AN projection matrix is obtained by maximizing signal-to-interference-plus-noise ratio (SINR) at the LUs. The proposed scheme only broadcasts the confidential message to the locations of LUs while the other regions are covered by AN, which promotes the security of the wireless broadcasting system. Moreover, it is energy efficient since the power of each LU is under accurate control. Numerical simulations are presented to validate the performance of the proposed scheme.
LED-Based Light Source Combined with Quantum Dot for Spectral Imaging
Authors: Bae Young Min , Kang Dong-Goo , Shin Ki Young , Lee Wonju , Yoo Dong-Wook
Published: May 2019

Quantum dot (QD) is a kind of semiconductor nanoparticle and shows photoluminescence, in which the light with narrow spectral band is emitted from the QD after the absorption of the excitation light. In this study, it is demonstrated that the LED-based light source combined with a QD film can be applied to spectral imaging. The polymer film with QD was prepared by photopolymerization. Through measurement of the emission spectrum, it was confirmed that the optical intensity at the peak wavelength of the spectral bands of 410 and 540 nm could be controlled by changing the thickness of the film. In the study using a home-made phantom mimicking blood vessels, the patterns’ contrast in the phantom images could be enhanced by using LED combined with QD as compared with the white light image. The LED light combined with the QD film provides a useful solution for illumination for spectral imaging.
Intramammary Angiomatoid Fibrous Histiocytoma, a Rare EWSR1 Rearranged Mesenchymal Neoplasm in a Previously Unreported Anatomic Location with Review of the Cleveland Clinic Experience
Authors: Bruehl F. K. , Cooper K. L. , Kilpatrick S. E. , Weindel M. D. , Ganea M. , Astbury C. , Downs-Kelly E. P. , Sturgis C. D.
Published: May 2019

Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor that is most commonly reported to arise in the subcutaneous tissues of the upper extremities in adolescents and young adults. At present, the WHO classifies this neoplasm as a tumor of uncertain differentiation. AFH is most often clinically regarded as a tumor of intermediate risk due to low reported rates of recurrence and only rare occurrences of metastases. Its histomorphological hallmarks are a prominent lymphoid cuff surrounding a spindle cell neoplasm with syncytial-appearing cytoplasm. Several variant morphologies have been described. Genetically, the tumor is characterized by translocations involving the EWSR1 gene in over 90% of cases. A widening range of anatomical locations and morphological variants of AFH has been reported in the literature; however, neither anatomic location nor specific morphologic features have been shown to correlate with clinical/biological behavior. We report a unique case of AFH arising in the parenchyma of the breast. The neoplasm showed the typical histomorphology including a peripheral lymphoid cuff. The lesional cells in this case were found to be immunoreactive with desmin, and a positive EWSR1 result was confirmed by break-apart fluorescence in situ hybridization testing. To our knowledge, this is the first report of AFH arising in the breast parenchyma of a postmenopausal female.
A Phase I Dose-Escalation Trial of BN-CV301, a Recombinant Poxviral Vaccine Targeting MUC1 and CEA with Costimulatory Molecules
Authors: Gatti-Mays Margaret E. , Strauss Julius , Donahue Renee N. , Palena Claudia , Del Rivero Jaydira , Redman Jason M. , Madan Ravi A. , Marté Jennifer L. , Cordes Lisa M. , Lamping Elizabeth , Orpia Alanvin , Burmeister Andrea , Wagner Eva , Pico Navarro Cesar , Heery Christopher R. , Schlom Jeffrey , Gulley James L.
Published: May 2019

Purpose:

BN-CV301 is a poxviral-based vaccine comprised of recombinant (rec.) modified vaccinia Ankara (MVA-BN-CV301; prime) and rec. fowlpox (FPV-CV301; boost). Like its predecessor PANVAC, BN-CV301 contains transgenes encoding tumor-associated antigens MUC1 and CEA as well as costimulatory molecules (B7.1, ICAM-1, and LFA-3). PANVAC was reengineered to make it safer and more antigenic.

Patients and Methods:

This open-label, 3+3 design, dose-escalation trial evaluated three dose levels (DL) of MVA-BN-CV301: one, two, or four subcutaneous injections of 4 × 108 infectious units (Inf.U)/0.5 mL on weeks 0 and 4. All patients received FPV-CV301 subcutaneously at 1 × 109 Inf.U/0.5 mL every 2 weeks for 4 doses, then every 4 weeks. Clinical and immune responses were evaluated.

Results:

There were no dose-limiting toxicities. Twelve patients enrolled on trial [dose level (DL) 1 = 3, DL2 = 3, DL3 = 6). Most side effects were seen with the prime doses and lessened with subsequent boosters. All treatment-related adverse events were temporary, self-limiting, grade 1/2, and included injection-site reactions and flu-like symptoms. Antigen-specific T cells to MUC1 and CEA, as well as to a cascade antigen, brachyury, were generated in most patients. Single-agent BN-CV301 produced a confirmed partial response (PR) in 1 patient and prolonged stable disease (SD) in multiple patients, most notably in KRAS-mutant gastrointestinal tumors. Furthermore, 2 patients with KRAS-mutant colorectal cancer had prolonged SD when treated with an anti-PD-L1 antibody following BN-CV301.

Conclusions:

The BN-CV301 vaccine can be safely administered to patients with advanced cancer. Further studies of the vaccine in combination with other agents are planned.

See related commentary by Repáraz et al., p. 4871
BRD4 Regulates Metastatic Potential of Castration-Resistant Prostate Cancer through AHNAK
Authors: Shafran Jordan S. , Andrieu Guillaume P. , Györffy Balázs , Denis Gerald V.
Published: May 2019

The inevitable progression of advanced prostate cancer to castration resistance, and ultimately to lethal metastatic disease, depends on primary or acquired resistance to conventional androgen deprivation therapy (ADT) and accumulated resistance strategies to evade androgen receptor (AR) suppression. In prostate cancer cells, AR adaptations that arise in response to ADT are not singular, but diverse, and include gene amplification, mutation, and even complete loss of receptor expression. Collectively, each of these AR adaptations contributes to a complex, heterogeneous, ADT-resistant tumor. Here, we examined prostate cancer cell lines that model common castration-resistant prostate cancer (CRPC) subtypes, each with different AR composition, and focused on novel regulators of tumor progression, the Bromodomain and Extraterminal (BET) family of proteins. We found that BRD4 regulates cell migration across all models of CRPC, regardless of aggressiveness and AR status, whereas BRD2 and BRD3 only regulate migration and invasion in less aggressive models that retain AR expression or signaling. BRD4, a coregulator of gene transcription, controls migration and invasion through transcription of AHNAK, a large scaffolding protein linked to promotion of metastasis in a diverse set of cancers. Furthermore, treatment of CRPC cell lines with low doses of MZ1, a small-molecule, BRD4-selective degrader, inhibits metastatic potential. Overall, these results reveal a novel BRD4–AHNAK pathway that may be targetable to treat metastatic CRPC (mCRPC).

Implications:

BRD4 functions as the dominant regulator of CRPC cell migration and invasion through direct transcriptional regulation of AHNAK, which together offer a novel targetable pathway to treat metastatic CRPC.

Visual Overview: http://mcr.aacrjournals.org/content/molcanres/17/8/1627/F1.large.jpg.
Heterogeneity in Colorectal Cancer Stem Cells
Authors: Hirata Akihiro , Hatano Yuichiro , Niwa Masayuki , Hara Akira , Tomita Hiroyuki
Published: May 2019

Cancer stem cells (CSC) have attracted a great deal of interest for their clinical relevance in a range of cancers, including colorectal cancer. CSCs were initially considered to be cell populations with homogeneous, well-defined phenotypic and molecular characteristics. However, accumulating evidence suggests that CSCs represent phenotypically and functionally heterogeneous populations. Recent studies demonstrate colorectal CSCs to be dynamic rather than static, and continuously altered by multiple extrinsic and intrinsic factors. Thus, CSCs no longer should be viewed as a fixed target population, and we should note that their heterogeneous and dynamic nature presents a serious problem for the development and implementation of specific therapeutic strategies. This review summarizes past and current literature related to the heterogeneity and dynamics of colorectal CSC populations, focusing on evidence for distinct subpopulations, and signaling pathways, and intra- and extratumoral factors involved in their regulation in cancer tissues.
TAS-120 Overcomes Resistance to ATP-Competitive FGFR Inhibitors in Patients with FGFR2 Fusion–Positive Intrahepatic Cholangiocarcinoma
Authors: Goyal Lipika , Shi Lei , Liu Leah Y. , Fece de la Cruz Ferran , Lennerz Jochen K. , Raghavan Srivatsan , Leschiner Ignaty , Elagina Liudmila , Siravegna Giulia , Ng Raymond W.S. , Vu Phuong , Patra Krushna C. , Saha Supriya K. , Uppot Raul N. , Arellano Ron , Reyes Stephanie , Sagara Takeshi , Otsuki Sachie , Nadres Brandon , Shahzade Heather A. , Dey-Guha Ipsita , Fetter Isobel J. , Baiev Islam , Van Seventer Emily E. , Murphy Janet E. , Ferrone Cristina R. , Tanabe Kenneth K. , Deshpande Vikram , Harding James J. , Yaeger Rona , Kelley Robin K. , Bardelli Alberto , Iafrate A. John , Hahn William C. , Benes Cyril H. , Ting David T. , Hirai Hiroshi , Getz Gad , Juric Dejan , Zhu Andrew X. , Corcoran Ryan B. , Bardeesy Nabeel
Published: May 2019

ATP-competitive fibroblast growth factor receptor (FGFR) kinase inhibitors, including BGJ398 and Debio 1347, show antitumor activity in patients with intrahepatic cholangiocarcinoma (ICC) harboring activating FGFR2 gene fusions. Unfortunately, acquired resistance develops and is often associated with the emergence of secondary FGFR2 kinase domain mutations. Here, we report that the irreversible pan-FGFR inhibitor TAS-120 demonstrated efficacy in 4 patients with FGFR2 fusion–positive ICC who developed resistance to BGJ398 or Debio 1347. Examination of serial biopsies, circulating tumor DNA (ctDNA), and patient-derived ICC cells revealed that TAS-120 was active against multiple FGFR2 mutations conferring resistance to BGJ398 or Debio 1347. Functional assessment and modeling the clonal outgrowth of individual resistance mutations from polyclonal cell pools mirrored the resistance profiles observed clinically for each inhibitor. Our findings suggest that strategic sequencing of FGFR inhibitors, guided by serial biopsy and ctDNA analysis, may prolong the duration of benefit from FGFR inhibition in patients with FGFR2 fusion–positive ICC.

Significance:

ATP-competitive FGFR inhibitors (BGJ398, Debio 1347) show efficacy in FGFR2-altered ICC; however, acquired FGFR2 kinase domain mutations cause drug resistance and tumor progression. We demonstrate that the irreversible FGFR inhibitor TAS-120 provides clinical benefit in patients with resistance to BGJ398 or Debio 1347 and overcomes several FGFR2 mutations in ICC models.

This article is highlighted in the In This Issue feature, p. 983
Identification key for the Brazilian genera and species of Aloninae (Crustacea, Branchiopoda, Anomopoda, Chydoridae)
Authors: Sousa Francisco Diogo Rocha , Elmoor-Loureiro Lourdes Maria Abdu
Published: May 2019

Since early 2000 years, the knowledge about the taxonomy of Aloninae (Cladocera: Chydoridae) has been in rapid progress. For this reason, the most of Brazilian fauna was affected concerning nomenclature, besides an increase in the number of known genera and species. Thus, in this study, we bring an updated species list of Aloninae in Brazil, as well as identification keys based in current nomenclature and morphological standards. Our finding pointed to the occurrence of 46 valid species, belonging to 21 genera and three groups of Alona sensu lato. Two of these genera are endemic to Brazil. So far, South-East Asia and Brazil have the most well-studied Aloninae fauna in the entire planet.
Discovery of the mud shrimp genus Anacalliax de Saint Laurent, 1973 (Decapoda: Callianassidae) in the Brazilian coast
Authors: Ferreira Luciane Augusto De Azevedo , Pachelle Paulo P.G.
Published: May 2019

Previously known only from Argentina and Uruguay, Anacalliax argentinensis is herein reported for the first time from Rio de Janeiro, representing the first occurrence of genus Anacalliax in the Brazilian coast and the northernmost record of the species in the Atlantic Ocean. Morphological variations on the third maxilliped and first pereopods are discussed based in our material.
Causes of Mortality After Percutaneous Coronary Intervention
Authors: Bricker Rory S. , Valle Javier A. , Plomondon Mary E. , Armstrong Ehrin J. , Waldo Stephen W.
Published: May 2019

Background:

Public reporting of percutaneous coronary intervention (PCI) often uses periprocedural (30 days) mortality as a surrogate for procedural quality, though it is unclear how often death is attributable to the PCI. The cause of death among patients who died within 30 days of PCI in a national healthcare system was thus evaluated.

Methods and Results:

We identified all patients who died within 30 days of PCI in the Veterans Affairs (VA) Healthcare System from October 2005 to September 2016. Causes of death were classified through a detailed chart review using definitions from the Academic Research Consortium. Of 115 191 patients undergoing PCI during the study period, 1674 patients died within 30 days of PCI (1.5%). A detailed chart review demonstrated that the majority of patients had an undifferentiated death not definitively attributable to a single cause (981, 59%), whereas a minority had a death directly attributable to a cardiovascular cause (467, 28%). The majority of cardiovascular deaths were unrelated to the interventional procedure (335, 72%). Cardiovascular deaths were more likely to occur in the inpatient setting (95%) compared with noncardiac (89%) or undifferentiated deaths (49%,
P
<0.001).

Conclusions:

A minority of deaths occurring after percutaneous revascularization were definitively due to cardiac causes, with an even smaller proportion related to the PCI. With such a small proportion of deaths directly attributable to the PCI, these data suggest that 30-day mortality may be an inappropriate metric to assess procedural quality.
Vaterschaftstests zwischen religiösem Recht und Medizintechnik: Abstammungsklagen im algerischen Familienrecht
Authors: Guénon Melanie
Published: May 2019

This article examines the 2005 Algerian family law regulations concerning paternity and the use of DNA tests in Algerian paternity disputes. Specifically, it analyzes the relation between the methods of establishing and negating paternity recognized in Islamic law and the available genetic technology. 

On the basis of three judgments of the Supreme Court, the present legislation as well as legal practice in Algeria is scrutinized. The article concludes that the Algerian legislator hesitates to dissolve the conflict between genetic technology and the recognized types of evidence of Islamic law. For now, court practice remains ‘traditional’ since judges might feel too much responsibility facing unclear regulations regarding paternity. Nevertheless, the Algerian family code reform offers the opportunity to use DNA-tests to establish nasab for both legitimate and illegitimate children. Due to unclear regulations it also paved the way to use DNA-analysis for paternity negation.*
Two new species of Parameletus Bengtsson, 1908 (Ephemeroptera: Siphlonuridae), and notes on other species from the Far East of Russia
Authors: TIUNOVA TATIANA M.
Published: May 2019

Two new species of Parameletus are described, increasing the number of species known from Far East of Russia to four: P. chelifer Bengtsson 1908, P. minor (Bengtsson 1909), and the new species P. ensiformis and P. arcuatus. Both new species are known from male imagines. P. minor is first recorded for the Southern Far East. Illustrations and a key for the male imagines of the known species of Parameletus from Russian Far East are provided. Distributional data are presented.
Species delimitation in the Drosophila aldrichi subcluster (Diptera: Drosophilidae) using DNA sequences
Authors: OLIVEIRA DEODORO C. S. G. , LEONIDAS MELISSA , ETGES WILLIAM J. , O’GRADY PATRICK M. , DESALLE ROB
Published: May 2019

DNA sequence data has been successfully used to verify current species-level taxonomic hypotheses based on morphology and other characters. Setting species boundaries in the Drosophila repleta group has been challenging because this group contains several cryptic taxa and morphologically polymorphic populations. Mitochondrial (cox1 and nad2) and nuclear (sina and Marf) genes were employed to assess species limits for two traditionally recognized, closely related, and taxonomically problematical species, D. aldrichi and D. wheeleri. Both tree-based and character-based methods were used to show that D. wheeleri is indeed a distinct species; however, our data shows that D. aldrichi is a paraphyletic assemblage of two lineages as previously suggested based on patterns of reproductive isolation. One lineage is sister to D. wheeleri and includes populations originating from southern and western Mexico (western-aldrichi). The second, basal group also contains flies from southern Mexico, along with populations from the northern and eastern regions within the species boundaries traditionally described as D. aldrichi (eastern-aldrichi). The populations of D. aldrichi that were introduced into Australia were found to be included in the eastern-aldrichi group. Our results, particularly those based on the rapidly evolving mtDNA sequences, confirm the presence of at least two cryptic species previously referred as “D. aldrichi”.
Review of mining flies of the genus Phytobia Lioy (Diptera: Agromyzidae): Western Palearctic species
Authors: ZLOBIN VLADIMIR V.
Published: May 2019

Phytobia pseudobetulivora is described as new to science (type-locality: Tajikistan, Gissar ridge, Kondara ravine). The key for identification of West Palaearctic Phytobia species is provided. New faunistic records are given. The neotype of Agromyza errans Meigen, 1830 is designated.
Four new Pseudosinella (Collembola: Entomobryidae) from La Rioja, Spain
Authors: BENITO JOSÉ C. SIMÓN , PALACIOS-VARGAS JOSÉ G.
Published: May 2019

Four new species of Pseudosinella from La Rioja, Spain are described and illustrated. They are P. logrognensis sp. nov., P. leivaensis sp. nov., P. gutierrezae sp. nov. and P. torcuatoensis sp. nov., which were found in soils of different field crops. Identification keys are given for some of them, based on the chaetotaxy or the number of eyes, in order to compare the new species with those having 5 + 5 eyes.
Four species of Mazocraeoides Price, 1936 (Monogenea: Mazocraeidae), including two new species from clupeiform fishes off Visakhapatnam coast, Bay of Bengal
Authors: SAILAJA BADE , SHAMEEM UMMEY , MADHAVI ROKKAM
Published: May 2019

Four species of Mazocraeoides Price, 1936 including two new species are recorded from clupeiform fishes collected from Visakhapatnam Coast, Bay of Bengal: M. rotundus n. sp. from Ilisha filigera, M. fusiformes n. sp. from Stolephorus indicus, M. prashadi Chauhan, 1950 from Sardinella longiceps and M. dussumieri Mamaev, 1975 from Dussumieria hasselti. Mazocraeoides rotundus n. sp. is differentiated from the previously described species of Mazocraeoides by possessing the following combination of characters: the small pot-like body, the distribution of clamps in the posterior half of body and the genital complex consisting of five pairs of hooks arranged in two vertical rows. It differs from M. prashadi in the body shape and the much smaller size of the genital complex. Mazocraeoides fusiformes n. sp. differs from all the other species of the genus in the distribution of the clamps embracing only the posterior part of the testis and the genital complex consisting of one pair of needle-like lateral hooks and five pairs of median hooks. Mazocraeoides prashadi is redescribed to fill the gaps existing in the earlier description. Mazocraeoides dussumieri recorded earlier from South China Sea is reported for the first time from the Bay of Bengal. The validity of various species of Mazocraeoides is discussed and a key for the separation of valid species is provided. A host-parasite list is presented which gives details of the hosts, the geographic distribution and the validity status for each species. A partial 28S rDNA sequence was generated for M. dussumieri and deposited in GenBank.
Critical Checklist of the Indian species of Hypogastrura (Collembola: Hypogastruridae) with a description of a new species from Satkosia Wild Life Sanctuary
Authors: MANDAL GURU PADA , ARBEA JAVIER
Published: May 2019

Ten Hypogastrura species have been found from India, two of which are described: H. unguiculata (Mitra, 1966) and H. satkosiaensis nov. sp. Two Indian species have been removed from Hypogastrura and have been included in the genus Ceratophysella based on their original descriptions: C. baltica (Tyagi & Baijal, 1982) comb. nov. and C. katraensis (Tyagi & Baijal, 1982) comb. nov. H. satkosiaensis sp. nov. belongs to H. manubrialis group of species within the genus and is easily separated from the other members of the group by a combination of characters, a greater number of antennal sensilla, dorsal chaetotaxy, specially presence of m1 chaeta on abdominal tergite V, and mucro shape. A key for all of the known Indian species of Hypogastrura is provided.
Taxonomic review of the genus Compsiluroides Mesnil (Diptera: Tachinidae), with the description of a new species
Authors: HUANG YU-ZEN , TACHI TAKUJI
Published: May 2019

Compsiluroides communis Mesnil, C. flavipalpis Mesnil and C. meifengensis sp. nov. are redescribed and described with illustrations. Compsiluroides proboscis Chao & Sun is treated as a junior synonym of C. communis. Variations of structures of the male postabdomen of C. communis are illustrated. The genus is newly recorded from Nepal and Taiwan. A key to the three known species of Compsiluroides is provided and their diagnostic characters are illustrated.
The description of Anacroneuria suerre sp. nov. from Costa Rica (Plecoptera: Perlidae) and using nymphs in ecotoxicological studies
Authors: BRAVO FRANCISCO , ROMERO DAVID , GUTIÉRREZ-FONSECA PABLO E. , ECHEVERRÍA-SÁENZ SILVIA
Published: May 2019

The lack of nymph-adult associations limits our knowledge of the ecology, history and sensitivity of aquatic insects. In this study, the new species, Anacroneuria suerre sp. nov is described from Costa Rica based on the male, female, and nymphal stages. We briefly discuss the use of Plecoptera in ecotoxicological studies.
Financial Management Activity Process: Qualitative inquiry of adults with acquired brain injury
Authors: Engel Lisa L. , Beaton Dorcas E. , Green Robin E. , Dawson Deirdre R.
Published: May 2019

Background.

Little is known about the financial management occupations of people living with brain injury, despite the importance of these to adult autonomy.

Purpose.

This work aims to develop a conceptual framework for financial management after adulthood acquired brain injury.

Method.

This qualitative study used grounded theory methods. Data included semistructured interviews of 10 adults living with brain injury and two close others who assist with financial management occupations. Analysis included initial and focused coding, memo writing, constant comparison, theoretical sampling of questions, and member checking.

Findings.

The Financial Management Activity Process conceptual framework describes a complex action process. This includes accounting for factors influencing financial choices and actions, and identifying and using a trusted personalized process, including using financial management strategies aligned with the constraints of factors.

Implications.

This conceptual framework may be useful to assessment and intervention development. It highlights the between-person and between-activity variability in financial management processes and strategy use.
E-therapy and social work practice: Benefits, barriers, and training
Authors: Cwikel Julie , Friedmann Enav
Published: May 2019

The use of information and communication technologies has greatly expanded and has far-reaching implications for social work practice. Following an international review of the literature, this study explored how social workers consider the issues associated with integration of e-therapy into their social work practice. A survey of Israeli social workers revealed that only 4 percent have actual experience with e-therapy. Respondents judged disabled persons and those with mobility restrictions, caregivers of the chronically ill, new parents, the chronically ill, and teenagers as the most appropriate target populations. Attitudes toward benefits, barriers, and training predicted the applicability of e-therapy in practice.
The Starry Universe of Johannes Kepler
Authors: Graney Christopher M.
Published: May 2019

Johannes Kepler described the Copernican universe as consisting of a central, small, brilliant sun with its planetary system, all surrounded by giant stars. These stars were far larger than, and much dimmer than, the sun – his De Stella Nova shows that every visible star must exceed the size of the Earth’s orbit, and the most prominent stars may exceed the size of the entire planetary system. His other writings, including his response to Ingoli, his Dissertatio cum Nuncio Sidereo, and his Epitome Astronomiae Copernicanae, also reflect this Copernican universe. To Kepler, such a universe was an illustration of divine power – and solid evidence against the stars being suns, against the universe of Giordano Bruno. Kepler’s starry universe was in fact the Copernican universe supported by observations of the stars, which showed them to have measurable apparent sizes. Not until the later seventeenth century were those apparent sizes shown to be spurious, allowing for a universe in which the stars were suns.
Histories of resistance, political violence, and revolutionary possibility in the neoliberal-era Naxalite novel
Authors: Walonen Michael K.
Published: May 2019

In recent years, there has been a marked upswing in fictional renderings of the 50-plus-year-old Maoist Naxalite movement among the authors of India and its sizable diaspora. This essay analyses how these attempts to give narrative-fictional form to the Naxalites, past or present, centrally entail taking a thematic position on the inegalitarian admixture of individualistic consumerism and profit-seeking, state and corporate power, and residual feudal agrarian landlordism defining contemporary neoliberal India, as well as on the extent to which the possibility of reforming this order posed by the Naxalites is desirable and able to be envisioned. Neel Mukherjee’s The Lives of Others poses the Naxalite movement in essentially ambiguous terms — highlighting the frequent ugliness of its struggle but also the brutality, dehumanization, and desperation it is born of, as well as the unquenchable hope sustaining it that a world different from the structural violence and systematic exploitation of Indian capitalism is possible. Jhumpa Lahiri’s The Lowland, on the other hand, largely bypasses addressing these roots of the Naxalite movement in the gross inequalities of Indian society and this reformist vision driving it, instead offering a bourgeois humanist vision of revolt in terms of its familial impact, permutated into something completely insular and compatible with the abiding individualist ethos and retrenchment of the state that are central to neoliberalism. Nilima Sinha’s Red Blooms in the Forest considers the deep-seated injustices structuring contemporary Indian society that spurs the Naxalites’ idealistic reformist social vision, but ultimately opts for a vision of bourgeois social reformism and noblesse oblige, stepping away from the possibilities of revolution and economic justice to affirm the neoliberal status quo of individualistic entrepreneurial self-advancement and top-down social amelioration through charitable giving.
Risk Seeking Moderates the Association Between Emotion Dysregulation and Cannabis-Related Consequences
Authors: Kentopp Shane D. , Johnson Nicholas , Fresquez Cara , Prince Mark A. , Conner Bradley T. ,   Marijuana Outcomes Study Team
Published: May 2019

Sensation seeking and emotion dysregulation have been identified as contributing factors for consequences associated with cannabis use, although findings have been mixed. The study seeks to clarify relations between sensation seeking, emotion dysregulation, and cannabis-related consequences. Cannabis users ( N = 2,128) were assessed for facets of sensation seeking, emotion dysregulation, and cannabis-related consequences. Results revealed a positive association between risk seeking and cannabis-related consequences, as well as between emotion dysregulation and cannabis-related consequences. A negative association was observed between experience seeking and cannabis-related consequences. An interaction was found between emotion dysregulation and risk seeking. Risk seeking appears to be a risk factor for cannabis-related consequences at lower levels of emotion dysregulation. At high levels, the effect of emotion dysregulation superseded that of risk seeking. These findings have implications for the prioritization of clinical concerns in individuals seeking treatment for problematic cannabis use.
Preserved ligature mark in postmortem decapitation
Authors: Kanchan Tanuj , Atreya Alok , Krishan Kewal
Published: May 2019

Examination of skeletonised remains for the cause and manner of death is a highly challenging task for forensic experts. We report an unusual case of postmortem decapitation following hanging with the presence of a well-preserved ligature mark in the partially skeletonised body. Careful death scene investigation, interpretation of circumstantial evidence and meticulous autopsy provided information on the cause and manner of death.
The National Economic Association at 50: Getting Back to Our Roots
Authors: Ajilore Olugbenga
Published: May 2019

The National Economic Association (NEA) started out as the Caucus of Black Economists in December 1969. At the onset of the 50th Anniversary of the NEA’s founding, this presidential address looks at the organization’s past, present, and future to improve the prospects for current and future African American economists. Three recommendations are offered: support The Review of Black Political Economy, the NEA’s journal; help develop regional student chapters; and continue to foster allies that are aligned with the NEA’s mission. The Economics field needs to be better about becoming diverse and inclusive, and the NEA can lead the movement toward those goals.
Foreword to “Nursing Home Performance: Organizational and Environmental Factors”
Authors: Weech-Maldonado Robert
Published: May 2019

This special collection explores the organizational and environmental factors influencing nursing home performance. The papers in this special collection fall into 3 broad themes. The first theme addresses issues related to nursing home quality measures and public reporting. The second group of papers examines how organizational resources and the environment may influence nursing home performance. The third group of papers examines the relationships among management, strategy, and performance. Findings from this special collection can inform managers and policy makers on best practices and policies that can enhance organizational performance and ultimately ensure access to long-term care.
Finding top performers through email patterns analysis
Authors: Wen Qi , Gloor Peter A , Fronzetti Colladon Andrea , Tickoo Praful , Joshi Tushar
Published: May 2019

In the information economy, individuals’ work performance is closely associated with their digital communication strategies. This study combines social network and semantic analysis to develop a method to identify top performers based on email communication. By reviewing existing literature, we identified the indicators that quantify email communication into measurable dimensions. To empirically examine the predictive power of the proposed indicators, we collected 2 million email archive of 578 executives in an international service company. Panel regression was employed to derive interpretable association between email indicators and top performance. The results suggest that top performers tend to assume central network positions and have high responsiveness to emails. In email contents, top performers use more positive and complex language, with low emotionality, but rich in influential words that are probably reused by co-workers. To better explore the predictive power of the email indicators, we employed AdaBoost machine learning models, which achieved 83.56% accuracy in identifying top performers. With cluster analysis, we further find three categories of top performers, ‘networkers’ with central network positions, ‘influencers’ with influential ideas and ‘positivists’ with positive sentiments. The findings suggest that top performers have distinctive email communication patterns, laying the foundation for grounding email communication competence in theory. The proposed email analysis method also provides a tool to evaluate the different types of individual communication styles.
Detection and correction of subtle context-dependent robot model inaccuracies using parametric regions
Authors: Mendoza Juan Pablo , Simmons Reid , Veloso Manuela
Published: May 2019

Autonomous robots frequently rely on models of their sensing and actions for intelligent decision making. Unfortunately, in complex environments, robots are bound to encounter situations in which their models do not accurately represent the world. Furthermore, these context-dependent model inaccuracies may be subtle, such that multiple observations may be necessary to distinguish them from noise. This paper formalizes the problem of detection and correction of such subtle contextual model inaccuracies in autonomous robots, and presents an algorithm to address this problem. The solution relies on reasoning about these contextual inaccuracies as parametric regions of inaccurate modeling (RIMs) in the robot’s planning space. Empirical results from various real robot domains demonstrate that, by explicitly searching for RIMs, robots are capable of efficiently detecting subtle contextual model inaccuracies, which in turn can lead to task performance improvement.
Investigating macrophage-mediated inflammation in migraine using ultrasmall superparamagnetic iron oxide-enhanced 3T magnetic resonance imaging
Authors: Khan Sabrina , Amin Faisal Mohammad , Fliedner Frederikke Petrine , Christensen Casper Emil , Tolnai Daniel , Younis Samaira , Olinger Anne Christine Rye , Birgens Henrik , Daldrup-Link Heike , Kjær Andreas , Larsson Henrik Bo Wiberg , Lindberg Ulrich , Ashina Messoud
Published: May 2019

Background

Initiating mechanisms of migraine headache remain poorly understood and a biomarker of migraine does not exist. Inflammation pertaining to the wall of cerebral arteries and brain parenchyma has been suggested to play a role in migraine pathophysiology.

Objective

We conducted the first experimental human study to investigate macrophage-mediated inflammation as a possible biomarker of migraine.

Methods

Using ultrasmall superparamagnetic iron oxide (USPIO)-enhanced 3T magnetic resonance imaging (MRI), we investigated the presence of macrophages in cerebral artery walls and in brain parenchyma of patients with migraine without aura. We used the phosphodiesterase-3-inhibitor cilostazol as an experimental migraine trigger, and investigated both patients who received sumatriptan treatment, and patients who did not. To validate our use of USPIO-enhanced MRI, we included a preclinical mouse model with subcutaneous capsaicin injection in the trigeminal V1 area. The study is registered at ClinicalTrials.gov with the identifier NCT02549898.

Results

A total of 28 female patients with migraine without aura underwent a baseline MRI scan, ingested cilostazol, developed a migraine-like attack, and underwent an USPIO-enhanced MRI scan > 24 hours after intravenous administration of USPIO. Twelve patients treated their attack with 6 mg s.c. sumatriptan, while the remaining 16 patients received no migraine-specific rescue medication. The preclinical model confirmed that USPIO-enhanced MRI detects macrophage-mediated inflammation. In patients, however, migraine attacks were not associated with increased USPIO signal on the pain side of the head compared to the non-pain side.

Conclusion

Our findings suggest that migraine without aura is not associated with macrophage-mediated inflammation specific to the head pain side.