bluuebunny/crossref_metadata_2025 huggingface dataset:
Experiencing Job Stress: Impediment Within the Course of Enhancement of Career Prospects
Authors:   Pedagogy and Organizational Culture in Nursery Schools, Delhi University, New Delhi, India., Kapur Dr. Radhika
Published: August 2024

The individuals, belonging to all occupations and socio-economic backgrounds have one of the major goals of getting engaged in employment opportunities. Within all types of organizations, individuals are in different job positions in accordance to the hierarchy. Within the course of putting into operation their job duties and responsibilities, they do get overwhelmed by certain factors, which enable them to be overwhelmed by job stress. In other words, in all types of job positions, individuals do get overwhelmed by the problem of job stress. There are number of factors, which enable them to be overwhelmed by this problem. Hence, throughout their jobs, they need to be well-informed in terms of their job duties and methodologies. Furthermore, they need to possess the abilities to work under stress. In addition, formation of positive viewpoints will be facilitating in doing well in one’s job duties and generating desired outcomes. As a consequence, all the members will render an important contribution in doing well in one’s job duties, achieving desired goals and objectives and meeting the expectations of individuals in leadership positions. The problem of job stress can be overcome on one’s own or through obtaining support and assistance from other members. Hence, it is of utmost significance to form cordial and amiable terms and relationships with each other. Therefore, job stress needs to be prevented from assuming a major form otherwise, it is considered as an impediment within the course of enhancement of career prospects. The main concepts that are taken into account in this research paper are, understanding the meaning and significance of job stress, causes of job stress and overcoming job stress is vital in leading to progression.
Promoting Enhancement of Working Conditions and Job Enrichment: Essential in Progression of Organizations and Human Resources
Authors:   Pedagogy and Organizational Culture in Nursery Schools, Delhi University, New Delhi, India., Kapur Dr. Radhika
Published: August 2024

Within all types of organizations, all the members, irrespective of their job positions in the hierarchy need to pay attention towards promoting enhancement of working conditions and job enrichment. Throughout their jobs, it is apparently understood that they pay adequate attention towards implementation of their job duties and responsibilities. In order to meet the expectations of individuals in leadership positions, achieve organizational goals and lead to up-gradation of overall structure of the organizations, one needs to be well-informed in terms of measures, which are necessary in promoting enhancement of working conditions and job enrichment. Within working environmental conditions, one needs to be well-informed in terms of the factor that there is a need to make provision of infrastructure, amenities and facilities. Furthermore, one needs to make use of various types of modern, scientific and innovative methods and materials. In addition, one needs to utilize these in an effective manner in order to lead to progression. Furthermore, all the members need to generate information and implement all the factors, which are facilitating in leading to progression. Therefore, it is well-understood, promoting enhancement of working conditions and job enrichment is essential in progression of organizations and human resources. The main concepts that are taken into account in this research paper are, understanding the meaning and significance of working conditions and job enrichment, measures to be implemented in promoting enhancement of working conditions and job enrichment and advantages of promoting enhancement of working conditions and job enrichment.
Teaching-Learning Methods and Materials: Indispensable in Achievement of Educational Goals
Authors:   Pedagogy and Organizational Culture in Nursery Schools, Delhi University, New Delhi, India., Kapur Dr. Radhika
Published: August 2024

In educational institutions of all levels, in order to promote student learning and lead to up-gradation of overall system of education, the teaching-learning methods and materials are regarded as the key. The educators are required to make use of these in an effective manner in order to achieve desired goals and objectives. With advancements taking place and with the advent of modernization and globalization, the educators are required to make use of different types of modern, scientific and innovative methods and materials. Understanding the concepts will be facilitating in generating desired outcomes. The educators need to be well-prepared. They need to possess adequate information in terms of their job duties and methodologies that are necessary to carry these out in a well-ordered manner. Hence, the students need to ensure they acquire an efficient understanding of the instructions that are given to them by educators. As a consequence, they will contribute efficiently in meeting the expectations of educators. Hence, in all grade levels, the educators and students are required to augment information in terms of different types of teaching-learning methods and materials. In order to be successful, the possession of these will be facilitating in carrying out all types of job duties and responsibilities in a satisfactory manner. Therefore, teaching-learning methods and materials are considered indispensable in achievement of educational goals. The main concepts that are taken into account in this research paper are, understanding teaching-learning methods, understanding teaching-learning materials and advantages of utilizing teaching-learning methods and materials.
POST-MORTEM CHANGES IN METABOLOMIC PROFILES OF HUMAN SERUM, AQUEOUS HUMOR, AND VITREOUS HUMOR
Authors: RIAZ L , SIDDIQUI AM , RASHID AN , SHAHID RA , NASRULHUDA . , BUTT F
Published: August 2024

Accurate post-mortem interval (PMI) estimation is crucial in forensic investigations, and metabolomic analysis of bodily fluids offers a promising approach. However, the suitability of ocular fluids for PMI estimation remains underexplored. Objective: The objective of this study was to evaluate the suitability of metabolomic analysis of ocular fluids, specifically vitreous humor (VH) and aqueous humor (AH), compared to serum for post-mortem interval (PMI) estimation and to identify the most promising metabolites for this purpose. Methods: A cross-sectional study was conducted at a tertiary care hospital in Karachi. Blood, AH, and VH samples were collected from human cadavers with PMIs ranging from 5 to 60 hours. Samples were prepared by removing proteins and lipids, followed by lyophilization. Metabolomic profiling was performed using an NMR Spectrometer. Pearson correlation coefficients were calculated to assess the relationship between metabolite concentrations and PMI. Results: The study identified 24 metabolites in blood, AH, and VH samples. Several metabolites, including glutamate, choline, glycine, and formate, exhibited significant positive correlations with PMI in all three fluids, with Pearson coefficients greater than 0.5. Notably, glutamate (blood: r = 0.585**, AH: r = 0.488*, VH: r = 0.683**), choline (blood: r = 0.435*, AH: r = 0.691**, VH: r = 0.713**), and glycine (blood: r = 0.553*, AH: r = 0.598**, VH: r = 0.690**) showed strong correlations. Conversely, glucose and pyruvate significantly negatively correlated with PMI in AH and VH. Conclusion: The findings indicate that VH and AH are more reliable than serum for PMI estimation due to their more stable metabolite profiles. Glutamate, choline, and glycine emerged as particularly promising biomarkers. The study supports the potential of metabolomic analysis of ocular fluids in forensic investigations to provide accurate PMI estimations.
ANALYSIS OF USE OF REMAINING MORE FINANCIAL BUDGET FINANCING, ANALYSIS OF THE USE OF BACKUP FUNDS AND DIVESTMENT ANALYSIS OF MANAGEMENT OF BUDGET INCOME BUDGET INCOME ON THE GOVERNMENT OF BINJAI CITY
Authors: Mariyam Mariyam
Published: August 2024

The purpose of this study was to determine and analyze whether the use of SiLPA last year, the use of reserve funds, the use of divestment on the management of the local budget in Binjai City Government. The analytical method used in my research is a quantitative method, by testing classic assumptions before getting a good research model. The variables in this study are the use of SiLPA last year, the use of reserve funds and the use of divestment as an independent variable and the level of APBD management as the dependent variable. The population of this study uses the Position of Financial Statements in 2014- 2015. The results of this study prove that partially the use of SiLPA last year, The use of Reserve Funds and the Use of Divestment have a significant effect on the Regional Budget Management in Binjai City. This is explained in the Adjusted R Square of 13.3%. The APBD management variable can be explained by the existing independent variables namely the use of SiLPA last year, Use of Reserve Funds and Use of Divestment have an effect on on APBD Management. The remaining 97.7% is influenced by other variables not explained by this research model, but the increase in acceptance of the use of SiLPA last year, the use of Reserve Funds, the use of Divestment, this is evidenced by the relationship has not been able to significantly improve the management of APBD. 3% of the APBD management variable can be explained by the independent variables, namely the use of SiLPA last year, the use of Reserve Funds and the use of Divestment have an effect on the APBD Management. The remaining 97.7% is influenced by other variables not explained by this research model, but the increase in acceptance of the use of SiLPA last year, the use of Reserve Funds, the use of Divestment, this is evidenced by the relationship has not been able to significantly improve the management of APBD. 3% of the APBD management variable can be explained by the independent variables, namely the use of SiLPA last year, the use of Reserve Funds and the use of Divestment have an effect on the APBD Management. The remaining 97.7% is influenced by other variables not explained by this research model, but the increase in acceptance of the use of SiLPA last year, the use of Reserve Funds, the use of Divestment, this is evidenced by the relationship has not been able to significantly improve the management of APBD
THE INFLUENCE OF SANCTIONS, QUALITY OF SERVICE AND SOCIALIZATION ON COMPLIANCEOFPAY TAX AND BUILDINGS IN PANTAI GEMI VILLAGE IN STABAT LANGKAT
Authors: Siregar Oktarini Khamilah
Published: August 2024

The purpose of this study is to analyze the influence of the sanctions, the quality of service and socialization to compliance to pay taxes the earth and buildings in the Village of Pantai Gemi Stabat Langkat simultaneously and partial. The population in this study is whole the head of the family to the taxpayer of the earth and the building is located in the Village of Pantai Gemi Stabat Langkat. Sampling technique in this research is the technique of simple random sampling technique using the slovin formula so that it obtained 96 the head of the family to the taxpayer of the earth and building the sample in this study of the 2500 head family to the taxpayer of the land and building be population. Methods of data analysis in this research using the model multiple linear regression with SPSS V17. The results in this study show that simultaneous sanctions, the quality of the services and socialization have significant positive impact compliance pay land and building tax and the partial sanctions, the quality of service and socialization have significant positive compliance pay land and building tax. The results of the test the coefficient of determination (R2 ) showed that the compliance to pay the tax of land and building able to described amounted to 34.9% by the sanctions, the quality of service and socialization, while the rest amounted to 65,1% influenced by other variables that are not included in this research that awareness the taxpayer, knowledge of taxation, level of education and the income of the taxpayer.
PENGGUNAAN QAWAID FIQHIYYAH DALAM BAHTSUL MASAIL NU
Authors: Jukhoir Syabrun
Published: August 2024

Tulisan ini menjelaskan Syari’at Islam adalah aturan-aturan Allah SWT, yang diciptakan untuk umat Islam yang dimanifestasikan oleh para mujtahid dalam literatur kitab-kitab fiqh, sebagai pedoman menuju kehidupan yang bahagia baik di dunia maupun di akhirat. Namun dalam kenyataannya produk-produk hukum yang terdapat dalam kitab-kitab fiqh tersebut tidak mampu menjawab persoalan-persoalan kontemporer yang sangat kompleks. Oleh karenanya, tuntutan untuk melakukan ijtihad oleh para intelektual/ ahli hukum Islam akan semakin mendesak, baik ijtihad secara individual (fardi) seperti pada masa-masa klasik maupun kolektif (jama`i).Pada zaman modern ini, di berbagai negara Islam, praktek ijtihad yang kedua yaitu ijtihad jama’i (kolektif), menjadi kecenderungan utama dan alternatif  bagi kebanyakan para ulama` atau ahli yang terhimpun dalam lembaga-lembaga formal yang dibentuk oleh negara atau lembaga-lembaga non formal dalam sebuah organisasi. Termasuk Lajnah Bahtsul Masail dibawah struktur NU. Lajnah ini merupakan lembaga lembaga yang bertugas menyelesaikan persoalan-persoalan fiqhiyyah yang terjadi di kalangan warga NU.
PERAN PENDIDIKAN AKHLAK DALAM MEMBANGUN KARAKTER MAHASISWA DI STMIK TRIGUNA DHARMA MEDAN
Authors: Al-Asy’ari Abu Hasan
Published: August 2024

Tujuan tulisan menjelaskan Pendidikan akhlak memiliki peran yang sangat penting dalam membangun karakter mahasiswa, khususnya di lingkungan perguruan tinggi seperti STMIK Triguna Dharma Medan. Penelitian ini bertujuan untuk menganalisis sejauh mana pendidikan akhlak berpengaruh dalam pembentukan karakter mahasiswa di STMIK Triguna Dharma. Metode penelitian yang digunakan adalah pendekatan kualitatif dengan teknik pengumpulan data melalui observasi, wawancara, dan studi dokumentasi. Hasil penelitian menunjukkan bahwa pendidikan akhlak yang diterapkan melalui berbagai program dan kegiatan di kampus memiliki dampak positif dalam membentuk karakter mahasiswa yang berintegritas, beretika, dan bertanggung jawab. Pendidikan akhlak juga berperan dalam menanamkan nilai-nilai moral yang esensial bagi kehidupan sosial dan profesional mahasiswa. Dengan demikian, pendidikan akhlak di STMIK Triguna Dharma Medan tidak hanya mendukung pencapaian akademik tetapi juga membentuk mahasiswa yang berkarakter baik dan siap menghadapi tantangan kehidupan.
TINJAUAN HUKUM ISLAM TERHADAP SANKSI DALAM PEMBATALAN PERTUNANGAN DI NAGARI GUGUAK MALALO KECEMATAN BATIPUH SELATAN KABUPATEN TANAH DATAR.
Authors: Mahmudi Elva , Dasrianto Vito
Published: August 2024

Tulisan ini mengkaji tentang tinjauan hukum Islam terhadap sanksi dalam pembatalan pertunangan di nagari Guguak Malalo. Permasalahannya adalah bahwa sistem adat di Nagari Guguak Malalo apabila terjadi pembatalan peminangan akan diberikan sanksi 1 (satu) rupiah emas. Pemberian sanksi ini sangant bertolak belakang dengan beberapa pandangan ulama mazhab sehingga ini akan sangat menarik untk diteliti. Tujuan dari penelitian ini adalah Untuk mengetahui bagaimana pelaksanaan sanksi dari pembatalan pertunangan di Nagari Guguak Malalo dan Juga Untuk menganalisis tinjauan hukum Islam terhadap sanksi pembatalan pertunangan. Jenis penelitian ini adalah sebuah kerja lapangan (field research), di mana untuk mendapatkan data-data dari permasalahan yang diteliti, penulis melakukan  observasi dan wawancara mendalam dengan narasumber kredibel yang ditentukan secara purposive. Adapun pengolahan data yang didapat dilakukan secara deskriptif-kualitatif. Alhasil, apabila setelah Pertunanganan ada pihak yang membatalkan tunangannya maka akan diberikan Sanksi 1 rupiah emas. Sanksi ini berlaku bagi kedua belah pihak yaitu pihak laki-laki dan pihak perempuan. Sanksi yang diberikan sudah menjadi kesepakatan niniak mamak selaku pemangku adat dan peraturan ini sudah dipakai oleh masyarakat secara turun menurun. Tujuannya adalah agar masyarakat tidak mudah memutuskan sebuah hubungan yang telah diikat. Ajaran Islam tidak mengatur secara khusus tentang sanksi bagi yang membatalkan pertunangan, tetapi kebiasaan (adat) yang berlaku di dalam kehidupan masyarakat, selagi tidak bertentangan dengan ajaran Islam, adat tersebut dibolehkan. Sebagian ulama menjelaskan bahwa hadiah yang diberikan di waktu meminang boleh diambil kembali selagi barangnya masih utuh dan sebagian lagi menjelaskan hadiah yang diberikan di waktu meminang sama halnya dengan hibah, sedangkan hibah tidak boleh diminta kembali.
Huck’s Voice versus Herd Mentality: The Good, the Bad, and the Evil
Authors: Chaleila Wisam Abughosh
Published: August 2024

In Mark Twain's 1884 chef-d‘œuvre, The Adventures of Huckleberry Finn (HF), the voice of innocence—personified by Huck Finn—evolves as a graphic reflection of his unique social and ethical standing, portraying him as a nonconforming, Adam-like wanderer seeking refuge in nature and searching for a distinct identity. Employing literary theory, this article goes beyond exposing the moral bankruptcy and hypocrisy in an allegedly ‘civilized’ white society that purports to uphold high moral standards. Drawing on Nietzsche's doctrine of good vs. bad and good vs. evil, along with the psychological phenomenon of herd mentality, the article demonstrates how Huck's voice challenges and destabilizes orthodox linguistic conventions, societal norms, ethical constructs, and long-standing beliefs in the antebellum American South during the nineteenth century. Key findings reveal that such a unique voice can be seen as a profound critique of the antebellum South’s values, introducing a newfangled perspective on America's development of a distinctive identity and its quest to establish its own voice and literature after severing ties with Britain.
Interactive Learning Landscapes: Leveraging Technology for Dynamic Education in the Writing Classroom
Authors: Ahmed Mahdi Aben
Published: August 2024

This study explores the perceptions of EFL learners towards interactive learning tools in the Saudi environment; it also investigates how available technology can be leveraged to create dynamic learning environments. Using a mixed methods approach, the study conducted a survey with 70 EFL learners and focus group interviews with 10 students across two higher education institutions to examine writing skill development using the three interactive writing tools, viz., Blackboard, Pear Deck, and Flipgrid. Results indicate that Saudi EFL learners in higher education have a moderately positive perception towards the integration of technology in the EFL classrooms, as well as support the efficacy of these interactive tools in aiding learning in the writing classrooms. Moreover, perceptional change evidently positively impacted learners’ writing as the performance in the post test showed an average improvement of between 19-24% in the scores This examination of the interaction between learners and digital resources is likely to uncover insights into effective strategies for enhancing English language learning experiences and outcomes, and benefit a range of stakeholders.
Efektivitas Penggunaan Media Augmented Reality untuk Meningkatkan Hasil Belajar Siswa pada Mata Pelajaran Ilmu Pengetahuan Alam Kelas VIII MTsN 1 Solok Selatan
Authors: Devitri Madella , Anugrah Septriyan , Eldarni Eldarni , Kurniai Reni
Published: August 2024

Technological advances that can be used to increase knowledge are the development of information technology in the field of education. This study aims to determine the effectiveness of using Augmented Reality media to improve student learning outcomes in Natural Sciences teaching mates. Quantitative methods are used in the research. This study used a Quasi Experiment design, members of the experimental group as well as controls were not randomly selected. This study uses a nonequivalent control group design. This design is almost the same as the pretest posttest control group design. In this study, the sampling technique uses a purposive sampling technique. Based on the output of "Test Statistics", it is known that Asymp.Sig(2-tailed) has a value of 0.001. The basis for decision-making in the Wilcoxon test is if the Asymp.Sig value is < 0.05, then the hypothesis is accepted, if the Asymp.Sig value is 0.05, the hypothesis is rejected. The results of the analysis showed that there was an influence of the use of Augemented Reality media on student learning outcomes and that the media was effectively used in learning. The learning outcomes of students in grade VIII of Natural Sciences subject applied in grade VIII 4 as an experimental class obtained a higher average score of 86.37 while the average score obtained in grade VIII 3 as a control class was lower with an average of 82.89
Haematology and Serum Biochemistry of Broiler Chickens on Dietary Supplementation of Garlic and Ginger Powder
Authors: Iheanacho Gabriella Chimuanya , Ajayi Emmanuel A , Sholademi E L , Abu O A , Akindoyin Matthew O , Abolude Abosede T , Judo Opeoluwa , Dahunsi Paul Olaoluwaniyi , Odoemene Elijah Chinedu
Published: August 2024

There is a correlation between the selection of commercially significant features in broiler chickens and a rise in production issues. The need for a nutritionally balanced diet has led to the usage of additives in broiler diets. Garlic and ginger both have strong chemical compounds that can be used medicinally in poultry. The purpose of this study is to ascertain the impact of adding garlic and ginger powder to the diet on the hematological and serum of chicken broilers. Five nutritional treatment groups were randomly assigned to 180 Arbor acres chicks, with three replicates of 12 birds each. There is no ginger or garlic in Treatment 1. There was 0.25% ginger and 0.25% garlic in treatments 2 and 3, respectively. In treatment 4, the proportion of ginger and garlic was 0.25%, whereas in treatment 5, the proportion was 0.50%. Over the course of 42 days, the experiment's hematological and serum were determined. The birds' packed cell volume, hemoglobin, white blood cells, platelets, lymphocytes, heterophil, monocyte, eosinophil, and basophil did not differ significantly. On the other hand, treatment 2, 3, and 5 have an impact (P<0.05) on the birds' red blood cells compared to control. Regarding the blood parameters of the birds fed this diet, there was no discernible change (P<0.05) seen for triglycerides, cholesterol, high-density lipoprotein, or low-density lipoprotein. The results show that while garlic alone or in conjunction with ginger can increase red blood cells, it has no effect whatsoever on serum when added at a rate of 0.25%.
Effect of Plastic and Organic Mulching on Soil Moisture Retention and Yield Response of Tomato under Furrow Irrigation
Authors: Gemeda Fekadu , Ahmed Bayan , Tilaye Asnake , Badeso Negash
Published: August 2024

One of the main causes of the low yield of tomatoes and low-quality products in Ethiopia’s Rift Valley is insufficient soil moisture during the crop-growing season. To overcome this challenge, a field trial was carried out at Tiyo woreda of Ketar Genat kebele to examine the effects of mulching and irrigation levels on soil moisture retention, water use efficiency, water productivity, and the yield of Halila variety tomatoes to determine the most efficient net return. The treatments were factorial design consisting of four mulching materials (white plastic, black plastic, wheat straw mulch, and no mulch) as the main plot and two water levels (100% ETc and 75% ETc) as sub-plot used with three replications. The interaction irrigation method and mulching types were highly significant at p<0.05 on soil moisture retention, water use efficiency, water productivity, and yield. The experiment’s findings showed that the interaction effect of white plastic mulch with 100%ETc produced the highest soil moisture retention, marketable yield, and total yield; however, it ranked fourth in WUE. The second was white plastic mulch with 75% ETc but was WUE, and the benefit-cost ratio was the first. The last was recorded at non-mulch. Therefore, based on the results of eight treatments in the experiment for tomato production, a combination of WPM with 75% ETc was advised for irrigation water management in keytar Genet Kebele and its surroundings and other similar agroecologies.
Avanços na imunoterapia para doenças autoimunes
Authors: Monteiro Bárbara de Oliveira Trindade , Pitanga Isadora Argôlo , Ramalho Neto João Crisóstomo , Pinto Luara Mendes Augustinho , Araujo Fernando Ribeiro
Published: August 2024

A resistência antimicrobiana (RAM) é um dos maiores desafios enfrentados pela medicina contemporânea, impactando significativamente as decisões clínicas e os resultados de saúde dos pacientes. Este estudo realizou uma revisão sistemática da literatura para analisar as principais causas e consequências da RAM em ambientes hospitalares, com foco na identificação de padrões de resistência em patógenos críticos, avaliação do impacto nas práticas terapêuticas e exploração de estratégias eficazes para mitigar seus efeitos. Foram revisados artigos publicados nos últimos dez anos, que abordam desde os mecanismos de resistência até as diretrizes terapêuticas mais recentes. Os resultados indicam que o uso indiscriminado de antimicrobianos, a inadequação de medidas de controle de infecções e a seleção natural de estirpes resistentes são fatores chave que contribuem para a escalada da resistência. Além disso, a RAM está associada a maiores taxas de morbidade e mortalidade, prolongamento das internações hospitalares e aumento dos custos de saúde. A implementação de estratégias baseadas em evidências, como a gestão rigorosa de antibióticos e o desenvolvimento de novas terapias, é essencial para combater este problema crescente. O estudo conclui que é necessário um esforço coordenado entre a prática clínica, a pesquisa e as políticas de saúde pública para enfrentar os desafios impostos pela resistência antimicrobiana.
Estado Hiperglicêmico Hiperosmolar (EHH): revisão abrangente sobre etiologia, fisiopatologia, diagnóstico, tratamento e prevenção
Authors: Almeida Ana Maria Rezende Machado , Costa Felipe Lemos Sales , Magagnin Gabriel Reveileau , Backes Gabriela Aline , Carvalho Giovanna Ribeiro de , Silva Júlia Brighenti Menezes , Vieira Júlia Diniz Marra , Amaral Juliana Oliveira , Ferreira Lurianny Dias , Pantuzza Marcella Ferreira , Donatti Maria Alice , Carrera Matheus Garcia , Martins Natália de Carvalho , Chagas Pedro Domingos Pita , Santos Taissa Ellen Ferrari
Published: August 2024

O Estado Hiperglicêmico Hiperosmolar (EHH) é uma condição grave associada à diabetes mellitus, caracterizada por níveis extremamente elevados de glicose e desidratação severa, sem a presença significativa de cetose. Este artigo fornece uma revisão abrangente sobre o EHH, abordando suas principais características, desde a etiologia e fisiopatologia até as manifestações clínicas, diagnóstico, tratamento, complicações, prognóstico e estratégias de prevenção e educação. O EHH geralmente resulta de um controle inadequado da diabetes, frequentemente exacerbado por fatores como infecções, condições críticas ou a interrupção de medicações. Os fatores de risco principais incluem desidratação severa e infecções, que contribuem para o desenvolvimento da condição. A fisiopatologia do EHH envolve hiperglicemia extrema e desidratação, elevando a osmolaridade sérica e comprometendo funções neurológicas. Clinicamente, o EHH se manifesta através de sintomas como polidipsia, poliúria, fraqueza, confusão e, em casos graves, pode levar ao coma. O diagnóstico é feito com base em exames laboratoriais que mostram glicose plasmática elevada e alta osmolaridade, com ausência de cetonemia significativa. O tratamento do EHH requer uma abordagem rápida e eficaz, que inclui a administração de fluidos intravenosos e insulina, além de monitoramento rigoroso dos eletrólitos para corrigir a desidratação e controlar os níveis de glicose. As complicações associadas ao EHH podem incluir insuficiência renal aguda e eventos tromboembólicos, e o prognóstico depende da rapidez no tratamento e da presença de comorbidades. A prevenção do EHH é fundamental e envolve a educação dos pacientes sobre o controle glicêmico adequado, a importância da hidratação e o reconhecimento precoce dos sinais e sintomas da condição. O suporte contínuo de profissionais de saúde é essencial para a gestão eficaz da diabetes e para a minimização do risco de episódios de EHH.
Abordagem cirúrgica para cálculos biliares: técnicas, complicações e perspectivas futuras
Authors: Cardoso Vitor Luís Aon Vieira , Souza Camila Fernandes de , Santos Clara Chagas Barbosa , Cherulli Daniela Espindula , Silva Danielle Patrício da , Pereira Gabriella Reis Granata , Sahão Henry Nakano , Mussi Higor Gomes , Lisbôa Leandra Alvarenga , Baptista Marcela Melo , Pires Marcella Moreira , Rosa Natasha Ohana Marinho , Tupper Natsue Tani , Reis Patrick Ribeiro , Benevides Vitória Chagas
Published: August 2024

A colecistectomia, a cirurgia para remoção da vesícula biliar, é a abordagem padrão para o tratamento de cálculos biliares e é amplamente considerada segura e eficaz. A técnica laparoscópica, desenvolvida como uma alternativa menos invasiva à cirurgia aberta, tem se tornado a escolha preferencial devido à sua menor taxa de complicações, menor tempo de recuperação e redução da dor pós-operatória. A cirurgia laparoscópica envolve a inserção de uma câmera e instrumentos através de pequenas incisões no abdômen, o que permite uma visualização direta e a remoção dos cálculos biliares com mínima invasão dos tecidos circundantes. Recentemente, técnicas avançadas, como a laparoscopia robótica, têm sido introduzidas para melhorar ainda mais a precisão e a eficácia do procedimento. As principais indicações para a colecistectomia incluem episódios recorrentes de dor abdominal, inflamação da vesícula biliar (colecistite) e complicações graves associadas aos cálculos biliares, como pancreatite e colangite. A escolha entre a abordagem laparoscópica e aberta depende de fatores como a complexidade do caso e a saúde geral do paciente. O manejo das complicações pós-operatórias e o acompanhamento rigoroso são essenciais para garantir uma recuperação bem-sucedida. Complicações como infecções, sangramentos e lesões aos ductos biliares podem ocorrer, mas a maioria dos pacientes experimenta alívio significativo dos sintomas e uma recuperação rápida. A qualidade de vida dos pacientes geralmente melhora substancialmente após a cirurgia, com a maioria relatando alívio das dores e melhora na função digestiva. O prognóstico a longo prazo é positivo, com baixa taxa de complicações graves e alta satisfação dos pacientes, desde que haja acompanhamento apropriado e manutenção da saúde digestiva. O sucesso da colecistectomia está intrinsecamente ligado à habilidade do cirurgião, à escolha da técnica adequada e ao seguimento pós-operatório eficaz.
Diabetes Mellitus gestacional - uma revisão de literatura
Authors: Rezende Arthur Ramos , Albuquerque Ana Luíza Carvalho , Santos Bárbara Aparecida Costa , Aguiar Bruna Sousa , Dutra Carolina Nunes , Vital Giovanna Almeida , Carvalho Isadora Rover de , Roque Júlia Braga , Oliveira Julia Cristina de , Jordão Juliana Alvarenga , Nomiya Juliana Melo , Augusto Lorena Reis , Grillo Luisa Werneck , Martins Maria Carmen Barbi , Amaral Maria Teresa Prata
Published: August 2024

A Diabetes Mellitus Gestacional (DMG) é uma condição metabólica caracterizada pela hiperglicemia que surge durante a gravidez. A epidemiologia da DMG mostra uma prevalência crescente globalmente, influenciada por fatores de risco como idade materna avançada, histórico familiar de diabetes, obesidade e etnia. As mulheres asiáticas, hispânicas e afro-americanas apresentam maior risco de desenvolver DMG. A fisiopatologia da DMG envolve a resistência à insulina exacerbada pelas mudanças hormonais da gravidez, levando à hiperglicemia. O diagnóstico precoce e preciso é crucial, sendo realizado principalmente através do Teste Oral de Tolerância à Glicose (TOTG) entre a 24ª e a 28ª semanas de gestação. Além do TOTG, métodos adicionais como a medição da hemoglobina glicada e glicemia casual podem ser utilizados para identificar casos de DMG. O monitoramento contínuo da glicemia é essencial para a gestão eficaz da condição, permitindo ajustes no tratamento conforme necessário. Modificações no estilo de vida, incluindo dieta balanceada e atividade física regular, são as primeiras linhas de tratamento para controlar os níveis de glicose no sangue. Em casos onde essas medidas não são suficientes, a terapia com insulina é geralmente implementada, considerada segura e eficaz durante a gravidez. Ademais, o uso de metformina pode ser considerado, embora seu impacto a longo prazo ainda requer mais estudos. A gestão multidisciplinar, que envolve obstetras, endocrinologistas, nutricionistas e educadores em diabetes, é fundamental para um tratamento bem-sucedido. Além disso, a educação sobre a condição e o treinamento em monitoramento glicêmico são componentes essenciais do cuidado. O acompanhamento pós-parto é vital para prevenir o desenvolvimento de diabetes tipo 2 em mulheres que tiveram DMG, enfatizando a importância de um estilo de vida saudável. Portanto, o manejo abrangente da DMG, desde o diagnóstico até o acompanhamento pós-parto, é essencial para minimizar riscos e promover a saúde materno-fetal.
Pengaruh Terapi Dzikir Terhadap Koping Pasien Di Instalasi Gawat Darurat
Authors: Devita Yeni , Puswati Desti , Nita Yureya , Alfianur
Published: August 2024

Dzikir merupakan terapi psikiatrik setingkat lebih tinggi dari pada psikoterapi biasa. Bacaan dzikir sangat ampuh mampu menenangkan, membangkitkan percaya diri, kekuatan, perasaan aman, tentram serta perasaan bahagia. Seorang individu ketika mengalami ansietas (kecemasan) menggunakan berbagai mekanisme koping untuk mencoba mengatasinya dan ketidak mampuan mengatasi ansietas merupakan penyebab utama terjadinya perilaku patologis. Tujuan umum dari penelitian ini adalah untuk mengetahui pengaruh terapi dzikir terhadap koping pasien di IGD RSUD kecamatan mandau kabupaten bengkalis. Desain penelitian  adalah Quasi eksperimen. Sampel pada penelitian ini 35 orang. Desain penelitian ini menggunakan pre-post test design without control. Uji stastitik menggunakan T-Test  Dependen. Hasil penelitian menunjukkan bahwa ada pengaruh terapi dzikir terhadap koping pasien di IGD RSUD kec mandau kabupaten bengkalis (P value 0,001 < 0,05). Disarankan kepada perawat agar mempraktekkan terapi dzikir dilapangan sehingga menciptakan koping adaptif antara perawat dan pasien dengan mengingat  Allah SWT dengan bacaan dzikir.
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In Silico Molecular Docking Senyawa Aktif Daun Bungur (Lagertroemia speciosa (L.)) Sebagai Inhibitor Reseptor Androgen Pada Kanker Prostat
Authors: Wiarti Agi , Humaedi Aji , Waluyo Dyah Ayuwati
Published: August 2024

Kanker prostat ialah penyakit ganas yang paling umum dan merupakan penyebab utama kematian. Senyawa aktif daun bungur (asam arjunolat, asam asiatat, asam oleonat, asam ursolat, dan asam virgatat) diketahui memiliki kemampuan dalam menghambat reseptor androgen. Tujuan penelitian ini adalah untuk mengetahui aktivitas inhibisi antikanker terhadap reseptor androgen, mengetahui nilai binding energi dan interaksinya terhadap reseptor androgen, mengetahui profil farmakokinetik senyawa hasil docking. Penelitian ini menggunakan metode docking molecular senyawa aktif daun bungur (Lagerstoremia speciosa (L.)) sebagai senyawa uji dan 1GS4 sebagai protein target dari reseptor androgen pada kanker prostat. In silico molecular docking ini menggunakan software AutodockTools, DiscoveryStudioClient, Pubchem, MarvinSketch, dan Prediksi ADMET menggunaka webserver ADMETlab 2.0. Berdasarkan hasil yang diperoleh berupa grup triterpene pentasiklik termasuk asam 23-hidroksiursolat, asam asiatat, asam oleanolat, asam arjunolat, asam korosolat, dan asam ursolat adalah beberapa senyawa kimia yang ditemukan dalam marga Lagerstroemia. Asam virgatat, asam kolosalat, asam ursolat, dan glikosida beta-sitosterol adalah beberapa triterpenoid yang pernah ditemukan di daun bungur hasil diperoleh asam virgatat menunjukkan hasil inhibisi dan nilai binding energi terbaik diantara senyawa aktif lainnya. Serta memiliki nilai farmakokinetik yang baik secara in silico.
Efektifitas Peer Group Education Terhadap Pengetahuan Dan Sikap Mengenai Anemia Pada Remaja Putri Di Pondok Pesantren
Authors: Yurisma Mitha , Agestika Lina , Hakiem Afrizal Sandra
Published: August 2024

Anemia pada remaja merupakan masalah kelaparan tersembunyi yang berdampak pada kondisi malnutrisi (gizi kurang) generasi selanjutnya. Anemia akibat kekurangan asupan zat gizi mikro yaitu zat besi dapat disebabkan oleh rendahnya pengetahuan dan sikap. Penelitian ini bertujuan untuk mengetahui efektivitas edukasi melalui teman sebaya (peer group education) terhadap pengetahuan dan sikap terkait anemia pada remaja putri di Pondok Pesantren Awwaliyah Al-Asiyah Cibinong. Penelitian ini menggunakan desain quasi-experimental dengan pretest-posttest control group. Sebanyak 60 santri putri di Pondok Pesantren Awwaliyah Al-Asiyah direkrut pada penelitian ini. Responden terdiri dari 4 edukator (pemberi pengetahuan) dan 56 responden yang dibagi rata menjadi 2 kelompok, yaitu kelompok peer group sebagai kelompok intervensi dan kelompok kontrol. Analisis data dilakukan menggunakan uji Wilcoxon dan Mann-Whitney. Hasil menunjukkan terdapat peningkatan pengetahuan dan sikap pada kelompok peer group (intervensi) dan terdapat perbedaan yang signifikan pada pengetahuan dan sikap (p-value <0,05). Pada kelompok kontrol terdapat peningkatan pada pengetahuan dan penurunan pada sikap, namun perbedaan tersebut tidak signifikan (p-value >0,05). Edukasi menggunakan metode peer group efektif dilakukan pada remaja, karena penyampaian informasi melalui teman sebaya dapat mencegah timbulnya rasa malu, takut, ataupun gugup untuk menyampaikan pendapat.
PENGARUH PROFITABILITAS DAN LEVERAGE PADA PENGHINDARAN PAJAK DENGAN KONEKSI POLITIK SEBAGAI VARIABEL PEMODERASI
Authors: Anggraini Kadek Angelita Armeitya Dwi , Noviari Naniek
Published: August 2024

The study attempts to gather empirical evidence of the influence of profitability and leverage on tax avoidance with the political connections serving as moderating variables. A mining sector business listed on the Indonesian Stock Exchange (IDX) for the 2018–2022 timeframe makes up the research population. Data analysis techniques are purposive sampling as well as samples selected of 22 companies with 110 observations. Moderate Regression Analysis is utilized to regress data with the help of Eviews 10. The research gains profitability and leverage has a positive effect on tax avoidance. Based on the experiments that have been conducted, the research can validate both the positive accounting theory and the agency theory. The practical implications of research can be used as a reference material for governments to enhance regulatory and supervisory capabilities as well as references for researchers for future advanced studies.
Strategi Representasi Eksternal Dalam Meningkatkan Keterampilan Kognitif Materi Hukum Newton Gerak Lurus
Authors: Hermawan Sapto , Parlindungan Sinaga  , Hikmat
Published: August 2024

External Representation is a learning strategy that is applied to convey the subject matter of teaching to students by using various modes of representation. The mode of representation consists of verbal representations, images, graphics, and mathematics. The application of the RE approach because learners experience learning obstacles to be able to understand newton's law of straight motion that is only conveyed verbally and mathematically. The purpose of this research is to train and improve students' cognitive skills in the domains of C1 (remembering), C2 (understanding), C3 (applying), and C4 (analyzing) in learning Physics. The research method used is a quasi-experimental design with a non-equivalent control group design. The subjects of this study were selected by purposive sampling. The students of class X Mathematics and Natural Sciences in a high school in West Bandung regency were 30 students in the experimental class and 30 students in the control class. Measurement of cognitive skills using multiple choice instruments on pre-test and post-test. Analysis to see the increase in students' cognitive skills using normalized gain analysis. The results obtained that the experimental class students have increased to the moderate category with a = 0.41 and students in the control class have a moderate category with a value of = 0.36 from each cognitive domain skill that is trained.
Implementasi Penanaman Adab dalam Pembelajaran Jarak Jauh di Pondok Pesantren Tahfidzul Qur’an
Authors: Pebri Azhari  , Uswatun Khasanah  , H. M. Yunan Hidayat
Published: August 2024

This research is motivated by the problems of schools or educational institutions in general related to how to most effectively educate and teach students through the Distance Learning system, especially related to instilling etiquette and morals to students in Islamic boarding schools labeled tahfidz quran. In educating etiquette and morals in Islamic boarding schools, it is usually done by giving examples to the students at the boarding schools concerned. The purpose of this study was to find out how to implement the cultivation of adab and morals during the pandemic during distance learning at the tahfidzul quran Islamic boarding school and what are the supporting and inhibiting factors in inculcating adab and morals when learning using a distance learning system using qualitative research methods with a case study approach. From this study, it can be seen that the cultivation of adab and morals is still considered by the teachers even though learning uses a distance learning system. The cultivation of etiquette and morals is also supported by several work programs built by teachers during distance learning, such as material delivery, example, habituation of routines, discipline, and evaluation. And also found several supporting and inhibiting factors during the process of inculcating etiquette and morals through the distance learning system.
Kepemimpinan Visioner Kepala Sekolah dalam Meningkatkan Pendidikan Pariwisata
Authors: Syam Aldo Redho , Nurjan Syarifan , Kurnianto Rido , Sumaryanti Lilis , Handayani Safitri Windi
Published: August 2024

This study aims to understand and analyze the visionary leadership of school principals in improving tourism education. Using this type of qualitative research with a phenomenological approach, the research target is at SMK Negeri 2 Ponorogo. Data collection techniques included in-depth interviews, participant observation, and documentation study. Data analysis techniques include data collection, condensation, data display, and drawing and verifying conclusions. The results showed that the principal's visionary leadership in improving tourism education at SMK Negeri 2 Ponorogo has been running effectively and efficiently by showing three dimensions: commitment, consistency, and competence. The principal's visionary leadership has also shown himself to be an “agent of change”, which consists of conceptual skills, technical skills, and human relations. The efforts of the principal of SMK Negeri 2 Ponorogo in improving tourism education are: (1) the ability of the principal to manifest his behaviour and attitude to his members; (2) the principal's ability to communicate verbally and non-verbally, supported by thinking out of the box; (3) the ability of the principal in identifying and solving problems with new techniques and methods and not being too cooperative; (4) the ability of the principal to leave doubts, be ready to take risks for innovation, and be open to doing different things; (5) the principal's ability to use the power of imagination, appreciation, intuition in making decisions.
Modal Sosial untuk Keberhasilan Madrasah Diniyah dalam Penyemaian Ideologi ke-Islaman dan Jawa
Authors: Subhin M. Abdillah , Anwar Saiful
Published: August 2024

Madrasah Diniyah Zumrotus Salamah since this educational institution emerged in the classical period, and its development is grappling with modernity while maintaining its identity as an Islamic educational institution which is a place for seeding Islamic and Javanese ideologies. This research focuses on social capital practised in Madrasah Diniyah Zumrotus Salamah as an institutional effort to instil Islamic and Javanese ideology. Using a qualitative and phenomenological approach, data were collected through in-depth interviews, observation and documentation. Data were analyzed by content analysis using an inductive approach and validity checking by data triangulation. The results of this study indicate that amid today's modernization, many individuals are far from morality. Through education at the Zumrotus Salamah Madrasah with the hybridization of the teachings of Religion and Javanese Custom, it is hoped that it can become a vessel for increasing self-religious piety. Islamic Dates and Dates of Perdikan Tawangsari Village, Adornment of body and clothing and Self-awareness of ana ing lathi, Study of Jawi culture is a social capital provided by Madrasah Diniyah Zumrotus Salamah to the students.
Tujuan Pendidikan Islam dalam Membentuk Generasi Berakhlak Mulia
Authors: Ramadhani Novia , Musyarapah
Published: August 2024

Penelitian ini bertujuan untuk membentuk generasi yang memiliki akhlak mulia dan memperdalam pemahaman tentang tujuan pendidikan islam dalam konteks pembentukan generasi berakhlak mulia. Metode dalam penelitian ini menggunakan metode kualitatif dengan pendekatan studi literatur untuk mendalami peran pendidikan Islam dalam membentuk generasi yang berakhlak mulia. Data yang dikumpulkan berasal dari berbagai literatur relevan seperti buku, artikel ilmiah, dan jurnal, yang kemudian dianalisis menggunakan teknik analisis konten. Teknik ini memungkinkan peneliti untuk mengidentifikasi, mengklasifikasikan, dan menginterpretasikan tema-tema utama yang muncul dari literatur, serta untuk memahami pola dan hubungan yang berkaitan dengan pembentukan akhlak mulia dalam pendidikan Islam. Melalui analisis ini, penelitian diharapkan dapat memberikan kesimpulan yang komprehensif mengenai kontribusi pendidikan Islam dalam pengembangan karakter generasi muda. Hasil dari penelitian ini menunjukkan aspek-aspek yang berkontrobusi dalam pembentukan akhlak mulia, yang pertama yaitu: menanamkan aqidah yang kuat kepada Allah SWT, yang kedua mengajarkan stariah islam yang berisi panduan mora dan juga etika kehidupan, yang ketiga yaitu membina karakter melalui pembiasaan dan yang terakhir adalah menciptakan lingkungan yang kondusif untuk menumbuhkan akhlak mulia. Maka dari itu dengan memberikan pendidikan islam sedari dini diharapkan generasi muda dapat menjadi individu yang berguna bagi agama, bangsa dan negara.
Effective School Management Through Total Quality Management
Authors: Venalia Agantina , Siti Dwiningrum  , Burgawanti
Published: August 2024

Realizing the quality of education that is good and remains controlled, there must be a national standard of school management. The purpose of this research is to analyze and describe in depth, through a literature review, effective school management through Total Quality Management (TQM). The study employs a qualitative method; the data is collected using a literature review that is critically and comprehensively reviewed. TQM in program implementation requires high commitment from the members or individuals involved. The eight TQM components should ensure the success of its activities. School principals play an important role because they must be able to develop, train, and implement these eight components in the implementation of educational programmes in schools. TQM will fail if it is not based on ethics, integrity and trust. Training for TQM empowerment as well as specific technical skills are essential for program implementation as they can create a work environment conducive to program objectives. The lack of communication between sections and implementers can be a burden or obstacle in the implementation of activities.