bluuebunny/crossref_metadata_2025 huggingface dataset:
“La imagen no enseña nada”: Notas sobre el problema del conocimiento en la teoría sartreana de lo imaginario
Authors: González Araneda Sergio
Published: May 2022

Nos proponemos abordar el estatuto epistemológico que le corresponde a la teoría sartreana de lo imaginario. Para esto, es necesario seguir dos líneas de análisis. En primer lugar, estableceremos similitudes y diferencias que presenta Sartre respecto del acto de percibir y el de imaginar. En segundo lugar, nos detendremos en una de las características fundamentales de toda conciencia que imagina: la creación intencional sobre el mundo. Finalmente, dilucidaremos el problema del estatuto epistemológico de la conciencia que imagina en directa relación con su carácter ontológico y estético. Con esto, daremos cuenta de la vigencia que posee el planteamiento sartreano respecto de la teoría fenomenológica de la imagen, la imaginación y lo imaginario.
Ciencia y alienación en la obra de Karl Marx
Authors: Rodriguez Chiarini Sebastian
Published: May 2022

En este trabajo analizamos el vínculo que Marx establece entre el fenómeno de la alienación capitalista y la ciencia, centrándonos en los efectos que dicho fenómeno tendría (según nuestro autor) tanto en las prácticas como en las teorías científicas. Para esto, nos valemos de la distinción, realizada en los Manuscritos económico-filosóficos, de cuatrodimensiones de la alienación (la alienación de los hombres respecto de sus productos, de los hombres respecto de su actividad, de los hombres respecto de la “esencia de su especie” y de los hombres entre sí). Observamos que estas cuatro dimensiones de la alienación son identificables no solo en la esfera económica, sino también en la científica y proveemosejemplos tomados de los textos de Marx.
Molecular Docking Studies of Glabrene and Human Epidermal Growth Factor Receptor Kinase
Authors: Katari Naresh Kumar , Gundla Rambabu , Reddy Phani Kumar , Vanam Anuradha , Talatam Aruna , Motohashi Noboru , Gollapudi Rao
Published: May 2022

Background: Human epidermal growth factor receptor 2 (Her2) gene located in human chromosome17, encodes Her2 tyrosine kinase protein, and is overexpressed in breast cancer cells. Her2 is activated on phosphorylation of tyrosine by adenosine triphosphate (ATP). Nonetheless, Her2 excessively partakes in the development and prognosis of specific types of aggressive breast cancers. Therefore, Her2 inhibition therapy is primary target for the treatment of aggressive breast cancer. At present, lapatinib is one of the Food and Drug Administration approved Her2 inhibitors used in cancer therapy. In molecular docking process, glabrene with slightly higher binding energy competitively bound to the active receptor site comparable to lapatinib and ATP. Therefore, glabrene could emerge as a potential candidate for restricting Her2 overexpressed breast cancer.

Objective: The present study aimed to demonstrate the inhibitory activity of glabrene, an isoflavene and xenoestrogen found in liquorice root, along with known Her2 inhibitor, lapatinib.

Methods: ATP, lapatinib, and glabrene were docked on human Her2 protein 3D structure which revealed glabrene as a competitive Her2 inhibitor akin to lapatinib. Results: The docking results suggested the binding site similarities of ATP, lapatinib, and glabrene. The binding energies of docked ATP, lapatinib, and glabrene complexes with Her2 were −9.1 kcal/mol, −10.5 kcal/mol, and −11.3 kcal/mol, respectively.

Conclusion: The in silico docking simulation of ATP, lapatinib, and glabrene suggested that glabrene is likewise a competitive Her2 inhibitor.
Integer Colorings with No Rainbow 3-Term Arithmetic Progression
Authors: Li Xihe , Broersma Hajo , Wang Ligong
Published: May 2022

In this paper, we study the rainbow Erdős-Rothschild problem with respect to 3-term arithmetic progressions. We obtain the asymptotic number of $r$-colorings of $[n]$ without rainbow 3-term arithmetic progressions, and we show that the typical colorings with this property are 2-colorings. We also prove that $[n]$ attains the maximum number of rainbow 3-term arithmetic progression-free $r$-colorings among all subsets of $[n]$. Moreover, the exact number of rainbow 3-term arithmetic progression-free $r$-colorings of $\mathbb{Z}_p$ is obtained, where $p$ is any prime and $\mathbb{Z}_p$ is the cyclic group of order $p$.
On Sum Sets and Convex Functions
Authors: Stevens Sophie , Warren Audie
Published: May 2022

In this paper we prove new bounds for sums of convex or concave functions. Specifically, we prove that for all $A,B \subseteq \mathbb R$ finite sets, and for all $f,g$ convex or concave functions, we have $$|A + B|^{38}|f(A) + g(B)|^{38} \gtrsim |A|^{49}|B|^{49}.$$

This result can be used to obtain bounds on a number of two-variable expanders of interest, as well as to the asymmetric sum-product problem. We also adjust our technique to prove the three-variable expansion result $$|AB+A|\gtrsim |A|^{\frac{3}{2} +\frac{3}{170}}\,.$$Our methods follow a series of recent developments in the sum-product literature, presenting a unified picture. Of particular interest is an adaptation of a regularisation technique of Xue, originating in a paper of Rudnev, Shakan, and Shkredov, that enables us to find positive proportion subsets with certain desirable properties.
Volatility Spillovers and Nexus across Oil, Gold, and Stock European Markets
Authors: Ren Chao
Published: May 2022

This paper utilises a trivariate VAR-BEKK-GARCH model to investigate the dynamic relationships between global oil price, gold price, and European stock markets. This paper observes weak return spillover effects from the oil market to 6 European stock markets (Netherlands, Lithuania, Portugal, Czech Republic, Romania, and Slovenia) and from gold to Iceland, while there is no evidence of return spillovers from stock markets to oil and gold. The non-existence of return linkages between gold and stock (oil) suggests that the gold market plays a haven role. With reference to volatility spillovers, the results show obvious asymmetric bidirectional volatility interaction between the European stock markets and the global oil/gold markets. Stronger shock and volatility contagions from the European stock market to both oil and gold markets are observed compared with the opposite direction. For the volatility nexus between oil and gold, weak and moderate evidence of shock and volatility transmission from gold to oil markets is reported. Additionally, the study documents important and effective empirical implications for portfolio management and investment hedge strategies: firstly, adding European stock markets to a diversified oil/gold portfolio can achieve the expected returns while reducing risk; and secondly, the European investors can use the gold and oil markets to hedge against their stock market portfolio.
Pengembangan Media Pembelajaran Interaktif Menggunakan Articulate Storyline Di Sekolah Dasar
Authors: Husain Rusmin , Ibrahim Ditya
Published: May 2022

Penelitian ini bertujuan untuk 1) mengetahui kondisi objektif pelaksanaan pembelajaran menggunakan media pembelajaran interaktif (articulate storyline) di kelas V SDN 9 Tilongkabila. 2) Untuk mengembangkan media pembelajaran interaktif (articulate storyline) pada mata pelajaran IPS materi peristiwa kebangsaan masa penjahan yang akan dikembangkan di kelas V SDN 9 Tilongkabila. 3) mengetahui kelayakan media pembelajaran berdasarkan penilaian ahli materi dan ahli media serta siswa. Metode yang dipakai pada penelitian adalah Research and Development (R&D) dengan tahapan pengembangan model ADDIE (Analysis, Design, Development, Implementation dan Evaluation), namun penelitian hanya dilaksanakan hingga tahap implementasi. Tehnik pengumpulan data dalam penelitian ini menggunakan angket validasi ahli materi dan validasi ahli media serta respon siswa, Media yang dikembangkan diujicoba oleh 14 siswa kelas V SDN 9 Tilongkabila. Media pembelajaran interaktif menggunakan articulate Storyline 3 pada mata pelajaran IPS Materi Peristiwa Kebangsaan Masa Penjajahan di kelas V SDN 9 Tilongkabila memperoleh rata-rata nilai dari ahli materi sebesar 90% yang dikategorikan sangat layak, selanjutnya untuk validasi ahli media memperoleh nilai rata-rata sebesar 89,17% yang memperoleh kategori sangat layak. Hasil penilaian pada uji coba yang dilakukan siswa memperoleh nilai rata-rata 92,32% dengan kategori sangat layak, sehingga media pembelajaran interaktif menggunakan articulate storyline 3 pada mata pelajaran IPS materi peristiwa kebangsaan masa penjajahan ini layak digunakan sebagai media pembelajaran interaktif di Kelas V Sekolah Dasar. Berdasarkan simpulan, maka dapat disarankan media pembelajaran interaktif menggunakan articulate storyline 3 pada mata pelajaran IPS materi peristiwa kebangsaan masa penjajahan dapat dimanfaatkan sebagai salah satu alternatif media pembelajaran yang dapat meningkatkan minat belajar siswa.
Mentoring Program: How it improves teachers ability to engage pupils in a variety of activities in kindergarten
Authors: Fitriani Somariah , Ilyas Hamzah Puadi
Published: May 2022

At the beginning of the learning process, class routines in the form of basic talks, songs and games are one way for kindergarten children to get used to practicing English at a young age and building their self-confidence to communicate with their friends. Thus, the aim of this study was to elaborate the mentoring activity in training teachers on how to incorporate various activities into the classroom routine. Four female teachers of an Islamic private Kindergarten participated in the mentoring program. This is a case study design of qualitative research with classroom observation and interviews. The study revealed that teachers were able to demonstrate some classroom activities through short dialogues, songs and games. It indicated that mentoring activity is found to provide participants with benefits and satisfaction, as well as the potential to motivate them to practice with kindergarten children in classroom.

 
The Effectiveness of Adolescent Reproductive Health Education on Attitude in Facing Pre Menstrual Syndrome in Students of Class X OTKP At SMKN 1 Binjai in 2018
Authors: Gultom Lusiana
Published: May 2022

One of the children's health efforts at community health center, established through the Presidential Instruction, is the Youth Care Health Service (PKPR), specifically aimed at increasing the knowledge and skills of adolescents about the reproductive health. Based on the Indonesian Health Profile, it was known that 11 provinces (32.4%) have not achieved the Strategic Plan target, set at 30%, in 2016, North Sumatra province reached 23.47%. Common problems in adolescents related to menstruation are dysmenorrhea (67.2%) and pre-menstrual syndrome (PMS) 63.1%. Pre-menstrual syndrome (PMS) is a collection of physical, emotional, psychological symptoms experienced by women during the luteal phase of each menstrual cycle (7-14 days before menstruation). This study aims to determine the Effectiveness of Adolescent Reproductive Health Education Against Attitudes in Facing Pre Menstrual Syndrome in Students of Class X OKTP at SMKN 1 Binjai 2018. This study used one group Pretest Postest design. All students of grade 10 OTKP, 83 people, became the population in this study, and the entire population was used as a research sample. The primary data, collected through questionnaire sheets, were analyzed by the Wicolxon Test. Through the research with the wicolxon test, it was found that the p value was 0,000, where the p value was 0,000 <α (0,05), then H0 was rejected which means that this research was meaningful, and this study concluded that adolescent reproductive health education was effective in increasing the attitude of female students in facing the pre menstrual syndrome. The results of the study are expected to be information and literature material for further research, health workers are also expected to provide child health counseling.
Evaluasi Pembelajaran Daring saat Pandemi Covid 19 Menggunakan Model Context, Input, Process, Product (CIPP)
Authors: Kaniawulan Ismi , Yusuf Syamsu
Published: May 2022

Pandemi Covid 19 telah memaksa proses pembelajaran dilakukan secara daring, proses adaptasi pengunaan teknologi informasi untuk pembelajaran daring tentunya tidak mudah sekalipun pembelajaran sudah berlangsung lebih dari satu tahun. Kesiapan elemen pendukung sistem pembelajaran mulai dari konsep, input, proses dan produk harus dievaluasi secara berkala. Permasalahan penelitian ini adalah bagaimana evaluasi pembelajaran daring selama covid-19 dengan model CIPP studi kasus mahasiswa program studi teknik informatika. Tujuan penelitian ini untuk mengevaluasi pembelajaran daring selama covid-19 dengan model CIPP pada mahasiswa program studi teknik Informatika. Hasil penelitian adalah kategori penilaian evaluasi pembelajaran dengan model CIPP.
The Chemical Composition of Extreme-velocity Stars*
†
Authors: Reggiani Henrique , Ji Alexander P. , Schlaufman Kevin C. , Frebel Anna , Necib Lina , Nelson Tyler , Hawkins Keith , Galarza Jhon Yana
Published: May 2022

Little is known about the origin of the fastest stars in the Galaxy. Our understanding of the chemical evolution history of the Milky Way and surrounding dwarf galaxies allows us to use the chemical composition of a star to investigate its origin and to say whether it was formed in situ or was accreted. However, the fastest stars, the hypervelocity stars, are young and massive and their chemical composition has not yet been analyzed. Though it is difficult to analyze the chemical composition of a massive young star, we are well versed in the analysis of late-type stars. We have used high-resolution ARCES/3.5 m Apache Point Observatory, MIKE/Magellan spectra to study the chemical details of 15 late-type hypervelocity star candidates. With Gaia EDR3 astrometry and spectroscopically determined radial velocities we found total velocities with a range of 274–520 km s−1 and mean value of 381 km s−1. Therefore, our sample stars are not fast enough to be classified as hypervelocity stars, and are what is known as extreme-velocity stars. Our sample has a wide iron abundance range of −2.5 ≤ [Fe/H] ≤ −0.9. Their chemistry indicates that at least 50% of them are accreted extragalactic stars, with iron-peak elements consistent with prior enrichment by sub-Chandrasekhar mass Type Ia supernovae. Without indication of binary companions, their chemical abundances and orbital parameters indicate that they are the accelerated tidal debris of disrupted dwarf galaxies.
How Do Magnetic Field Models Affect Astrophysical Limits on Light Axion-like Particles? An X-Ray Case Study with NGC 1275
Authors: Matthews James H. , Reynolds Christopher S. , Marsh M. C. David , Sisk-Reynés Júlia , Rodman Payton E.
Published: May 2022

Axion-like particles (ALPs) are a well-motivated extension to the standard model of particle physics, and X-ray observations of cluster-hosted AGN currently place the most stringent constraints on the ALP coupling to electromagnetism, g

a
γ
, for very light ALPs (m

a
≲ 10−11 eV). We revisit limits obtained by Reynolds et al. using Chandra X-ray grating spectroscopy of NGC 1275, the central AGN in the Perseus cluster, examining the impact of the X-ray spectral model and magnetic field model. We also present a new publicly available code, ALPro, which we use to solve the ALP propagation problem. We discuss evidence for turbulent magnetic fields in Perseus and show that it can be important to resolve the magnetic field structure on scales below the coherence length. We reanalyze the NGC 1275 X-ray spectra using an improved data reduction and baseline spectral model. We find the limits are insensitive to whether a partially covering absorber is used in the fits. At low m

a
(m

a
≲ 10−13 eV), we find marginally weaker limits on g

a
γ
(by 0.1–0.3 dex) with different magnetic field models, compared to Model B from Reynolds et al. (2020). A Gaussian random field (GRF) model designed to mimic ∼50 kpc scale coherent structures also results in only slightly weaker limits. We conclude that the existing Model B limits are robust assuming that β
pl ≈ 100, and are insensitive to whether cell-based or GRF methods are used. However, astrophysical uncertainties regarding the strength and structure of cluster magnetic fields persist, motivating high-sensitivity RM observations and tighter constraints on the radial profile of β
pl.
L’inconscient contaminé par la réalité
Authors: Franckx Christine
Published: May 2022

La crise climatique s’est inscrite dans la vie psychique des citoyens, elle a bien infiltré les rêves et contaminé l’inconscient. Cela est pourtant peu signifié dans le matériel psychique en séance, malgré le fait que ses effets sont omniprésents dans le monde externe. Dans cet article, le problème complexe de la crise environnementale est abordé sous un angle psychanalytique. Des hypothèses pour le désavouement généralisé dans la vie quotidienne ainsi que dans l’approche analytique de cette catastrophe pour l’humanité sont proposées. Dans la deuxième partie de l’article, l’auteur évoque des pistes pour « rêver » la relation de l’être humain avec son environnement naturel, ce qui pourrait faciliter une intégration intrapsychique et repositionner l’homme dans sa grande famille écobiologique. Ainsi le clivage résultant d’un vécu de contamination traumatisant de la vie psychique par des circonstances extérieures pourrait commencer à être levé. L’impact psychique de la crise climatique se trouve à la croisée des chemins de la psychopathologie individuelle et collective.
Sur la Commune de Paris
Authors: Coulon Patrick
Published: May 2022

La commémoration des 150 ans de La Commune n’est pas passée inaperçue. De nombreuses initiatives l’ont accompagnée au cours de l’année 2021. Les revues y ont pris leur part. Leur diversité témoigne de la place qu’a aujourd’hui prise cet épisode historique dans l’imaginaire identitaire de notre pays. Mais il reste un enjeu idéologique. Sans chercher l’exhaustivité, nous signalons, dans cet article, quelques-unes de ces revues.
La quête inachevée de la singularité disciplinaire
Authors: Déloye Yves
Published: May 2022

Cet article entend contribuer à une histoire sociale de la science politique à travers l’étude critique de l’institution particulière qu’est la Revue française de science politique ( RFSP ) : il s’agit de mieux comprendre ce que l’histoire d’une revue apporte à la compréhension de la genèse d’une discipline scientifique et ce que l’évolution de celle-ci fait à l’histoire d’une revue. Au-delà du contenu des articles publiés qu’une histoire intellectuelle privilégierait à raison, il s’agit de regarder du côté des acteurs qui ont fait la revue – et partant la discipline à cette époque fondatrice – et des choix éditoriaux qui ont été les leurs (ce que nous appellerons le « paratexte » de la revue). Loin de révéler une structuration rapide de la science politique française, l’enquête menée sur les premières décennies de l’histoire de la revue (1951-1970) permet de rendre compte du pragmatisme des pères fondateurs de la RFSP , de leur souci de doter la discipline des outils méthodologiques et des références (notamment bibliographiques) qui justifieront ses développements ultérieurs, bref des bricolages et hésitations qui sont souvent au fondement des connaissances scientifiques.
L’urgence écologique vue du Sud
Authors: Kolinjivadi Vijay , Jouy Élisabeth
Published: May 2022

Pour relever le défi de l’urgence écologique, le Green New Deal devra être « décolonial ». Il devra rompre avec le modèle dominant et l’occidentalisation du monde, par le démantèlement des structures néocoloniales et des mécanismes d’exploitation des peuples et de leur environnement. Il ne sauvera la planète qu’en visant l’égalité sociale, raciale et de genre, la relocalisation de l’économie et de nouveaux rapports à la nature.
Au-delà de l’attentat de Marseille du 9 octobre 1934
Authors: Bausardo Thomas
Published: May 2022

L’attentat de Marseille du 9 octobre 1934, qui voit la mort du roi Alexandre de Yougoslavie et du ministre français des Affaires étrangères Louis Barthou, occupe une place centrale dans la relation entre la France et la Yougoslavie durant l’entre-deux-guerres, mais n’épuise pas la manière dont le terrorisme l’a façonnée. Les années qui précèdent l’attentat connaissent en effet le développement d’une coopération antiterroriste en matière policière et de renseignement entre les deux États contre les menaces représentées par l’ORIM et l’Oustacha. Cette coopération est mise à l’épreuve lors de l’enquête consécutive à l’attentat de Marseille et se délite alors que la Yougoslavie se rapproche de l’Allemagne nazie.
Fostering Resilience in Nursing Students in the Academic Setting: A Systematic Review
Authors: Diffley Donna Marie , Duddle Maree
Published: May 2022

Background:

Nursing students experience similar stress-related health issues as RNs and have been identified as a group of health professionals who may be unable to cope effectively with stress. Studies have emphasized the need to incorporate resilience programs at higher education institutions for nursing students. However, it is important to identify strategies that increase resilience to ensure future programs are effective and follow an evidence-based approach.

Method:

This mixed-methods systematic review was conducted using Joanna Briggs Institute (JBI) methodology. A comprehensive literature search was conducted using JBI Critical Appraisal Checklists for assessment and quality appraisal. Data were extracted and synthesized thematically.

Results:

Category intervention strategies were identified and used to cluster three intervention strategy themes. Three outcome themes also were synthesized to examine strategy effectiveness.

Conclusion:

Findings indicate multicomponent interventions that include information sharing, skill application, and reflective learning are effective in helping nursing students manage stress and increase resilience.

[
J Nurs Educ
. 2022;61(5):229–235.]
Enhancing the Nursing Student Experience: A Mixed-Methods Approach
Authors: Jackson Molly
Published: May 2022

Background:

There is a lack of published literature linking the nursing student experience and program evaluation relationship. A mixed-methods approach was used to improve the nursing student experience through faculty, staff, and student engagement.

Method:

A student experience initiative was launched in 2016. A 3-year plan was developed by an external consultant and steering committee. A process to prioritize improvement needs across all programs was used, with program-specific plans, faculty engagement, and results in a graduate-entry nursing program.

Results:

Student satisfaction ratings on exit surveys increased from 1 of 10 at the start of the initiative in 2016 to 8 of 10 in 2021. Continuous improvement and engagement are needed to maintain student satisfaction in nursing education.

Conclusion:

This initiative can serve as a framework for other educational partners to consider adopting to enhance the nursing student experience and improve program outcomes.

[
J Nurs Educ
. 2022;61(5):276–279.]
Nursing Student and Faculty Perceptions of Just Culture
Authors: Hays Deana , Kruse Julie A.
Published: May 2022

Background:

Just culture is essential for quality improvement and patient safety.

Method:

This descriptive study measured perceptions of just culture among nursing students and faculty using the Just Culture Assessment Tool for Nursing Education (JCAT-NE).

Results:

There were no significant differences in JCAT-NE scores for students (
M
= 133.43,
SD
= 19.12) and faculty (
M
= 136.34,
SD
= 22.73) (t[159] = 0.82,
p
= .42); however, there were significant differences in JCAT-NE scores based on level of experience. For students, JCAT-NE scores were significantly higher for sophomores than for seniors (F[2, 114] = 4.9,
p
= .01). For faculty, advanced beginner and competent faculty had significantly higher scores compared with proficient and expert faculty (t[42] = 2.36,
p
= .02).

Conclusion:

More needs to be done to establish a fair and just culture in schools of nursing.

[
J Nurs Educ
. 2022;61(5):257–260.]
Perceived Expressed Emotion and Irritability in Adolescents With Attention-Deficit/Hyperactivity Disorder Inattentive Type: The Moderating Effect of Subtype
Authors: Uçar Halit Necmi , Çetin Fatih Hilmi , Türkoğlu Serhat
Published: May 2022

The current study aimed to investigate perceived expressed emotion (EE) and irritability among adolescents with inattentive and combined type attention-deficit/hyperactivity disorder (ADHD-I and ADHD-C, respectively), and to assess whether the subtype plays a moderating role in the relationship between perceived EE and irritability. The current cross-sectional, case-control study comprised 37 adolescents with ADHD-I, 62 adolescents with ADHD-C, and 58 age- and sex-matched adolescents without ADHD. After controlling for confounding factors, adolescents with ADHD-C were found to exhibit significantly higher levels of perceived lack of emotional support than adolescents with ADHD-I (
p
= 0.029). Results of moderation analysis showed ADHD subtype to be a moderating factor in the relationship between perceived EE and irritability. [
Journal of Psychosocial Nursing and Mental Health Services, 60
(10), 11–20.]
A Pilot Study to Develop the Rapid Estimate of Adult Literacy in Audiology
Authors: Ou Hua
Published: May 2022

Background:

Health literacy describes an individuals' ability to maximize their potential in health care, including one's ability to understand information needed to make informed health decisions. A variety of general and condition-specific health literacy assessment tools have been created to help health professionals assess patients' health literacy skills and tailor the need for health care communication or education; however, there are no such tools available for the audiology field.

Objective:

The purpose of the study was to develop an objective reading recognition audiology-related health literacy assessment tool, the Rapid Estimate of Adult Literacy in Audiology (REALA).

Methods:

This was a cross-sectional study (
N
= 200). The initial version of the REALA contained 99 words specifically related to audiology. The final version, revised to have improved clinical utility, contained a total of 48 words that were selected based on item difficulty, item discrimination score, and point-biserial index using classical item analysis.

Key Results:

The total pass rate for the final version of the 48-word REALA was 0.72 (standard deviation = 0.45) and the Cronbach coefficient alpha was 0.93. Once the comprehension component is added to the tool, the REALA can be a valuable health literacy assessment tool that health professionals use to evaluate patients' audiology-related health literacy.

Conclusion:

Once the comprehension component is added to the tool, the REALA can be a valuable health literacy assessment tool that health professionals use to evaluate patients' audiology-related health literacy.

[
HLRP: Health Literacy Research and Practice
. 2022;6(2):e88–e95.]

Plain Language Summary:

A health literacy assessment tool, the REALA, was developed in the study. The final version of REALA contained 48 words relative to hearing healthcare. The results suggested that REALA can help health professionals assess patients' hearing related health literacy and tailor the need for hearing health care communication or education.
Professional Responsiveness to Health Literacy: A Scoping Review
Authors: Cesar Flaviane Cristina Rocha , Moraes Katarinne Lima , Brasil Virgínia Visconde , Alves Angela Gilda , Barbosa Maria Alves , Oliveira Lizete Malagoni de Almeida Cavalcante
Published: May 2022

Background:

Difficulty in understanding and using health information can harm the patient and increase the cost of care provided. So, this study classified and mapped the characteristics and interventions that make health care professionals responsive to the patient's health literacy.

Methods:

Medline (PubMed), CINAHL (EBSCO), PsycInfo, ERIC (ProQuest), Lilacs (BVS) and EMBASE (Elsevier) were searched using a combination of controlled descriptors. The selected studies needed to address the concept or main focus of the study among health care professionals in the care or academic environment.

Key Results:

After reviewing 34 articles, 14 definitions and 10 subcategories of responsiveness were identified, and a broad characterization of health professional responsiveness to health literacy was proposed. Professional responsiveness to health literacy was characterized as knowing the definition and implications of health literacy for the patient's well-being and being able to develop, adapt, implement, and evaluate health education strategies. Nineteen strategies were mapped for education to ensure professional responsiveness to health literacy, classified as (A) expository (
n
= 18; 94.7%), (B) interactive (
n
= 9; 47.4%), (C) practice with educational materials (
n
= 2; 10.5%), (D) practice with standardized patient or simulation (
n
= 8; 42.1%), and (E) practice with actual patients (
n
= 4; 21.1%).

Discussion:

These characteristics and interventions provide a useful taxonomy for the development of curricula and professional education programs, and for the validation and use of measures to evaluate the health workforce. [

HLRP: Health Literacy Research and Practice
. 2022;6(2):e96–e103.

]

Plain Language Summary:

We found 14 definitions and 10 categories of professional responsiveness to health literacy. Professional responsiveness to health literacy was characterized as knowing the definition and implications of health literacy for the patient's well-being and being able to develop, adapt, implement, and evaluate health education strategies. Nineteen strategies were mapped for education to ensure professional responsiveness to health literacy.
The finite time blow-up for Caputo-Hadamard fractional diffusion equation involving nonlinear memory
Authors: Li Zhiqiang
Published: May 2022

In this article, we focus on the blow-up problem of solution to Caputo-Hadamard fractional diffusion equation with fractional Laplacian and nonlinear memory. By virtue of the fundamental solutions of the corresponding linear and nonhomogeneous equation, we introduce a mild solution of the given equation and prove the existence and uniqueness of local solution. Next, the concept of a weak solution is presented by the test function and the mild solution is demonstrated to be a weak solution. Finally, based on the contraction mapping principle, the finite time blow-up and global solution for the considered equation are shown and the Fujita critical exponent is determined. The finite time blow-up of solution is also confirmed by the results of numerical experiment.
La carrera militar en Filipinas en el siglo XVIII y sus relaciones con la política y el comercio. El caso del general Pedro Zacarías Villarreal
Authors: Aguilar Escobar Antonio
Published: May 2022

Nuestro trabajo pretende aportar nuevos datos y testimonios sobre la relación entre militares, política y negocios en Filipinas en la primera mitad del siglo XVIII, a través de la carrera y vicisitudes de un oficial del ejército en el archipiélago, el general Pedro Zacarías Villarreal. Para ello, veremos la biografía del personaje y sus diferentes destinos en la milicia y en la administración, sus conflictos con las autoridades civiles, etc. Asimismo, comentaremos las características de los diversos cargos que ocupó, lo que nos ilustrará sobre el funcionamiento de ciertos puestos en el ejército poco estudiados hasta ahora, tales como las castellanías de las fortalezas o los gobiernos de algunos presidios, por ejemplo, el de Zamboanga en la isla de Mindanao. El artículo se basa en la documentación original conservada en el Archivo General de Indias (AGI) y en la bibliografía existente sobre el tema.
El comercio interprovincial de esclavos en el nororiente del Nuevo Reino de Granada en la primera mitad del siglo XVIII
Authors: Salazar Carreño Robinson , Castaño Pareja Yoer Javier
Published: May 2022

Con base en la consulta y análisis de fuentes notariales provenientes de diferentes centros documentales del oriente colombiano, en este artículo se analiza el comercio de cautivos y la dinámica interna del mercado esclavista que existía entre las comarcas nororientales del Nuevo Reino de Granada en la primera mitad del siglo XVIII. De este modo, se describen los rasgos poblacionales, geográficos y económicos de los centros urbanos que integraban aquel espacio: Pamplona, Girón, San Gil y Villa de Leiva. Posteriormente, se examinan las características demográficas de esta población, un tema hasta el momento marginado en la historiografía colombiana, y se destaca cómo el régimen esclavista de aquella zona se sustentaba más en esclavos criollos que en africanos. Asimismo, se estudian las rutas y circuitos provinciales e interprovinciales del tráfico esclavista de aquel espacio y los tipos de cautivos que se negociaban cotidianamente, sus precios y las edades más demandadas en aquel mercado.
Ôter les habits du genre. Les modes d’action des Femen
Authors: Mesbah Jallal
Published: May 2022

Les militantes du mouvement féministe Femen, né en Ukraine en 2008, manifestent seins nus. Se dénuder pour des raisons politiques ne fait pas l’unanimité parmi les féministes. À partir d’entretiens avec des militantes, cet article porte sur le sens de la nudité politique pour les militantes elles-mêmes et les effets de ce mode d’action sur le genre. L’analyse de la mobilisation seins nus éclaire de quelle manière les militantes parviennent à dépasser les interdits de la nudité et les raisons qui poussent ces activistes à persévérer dans un militantisme qui demeure perçu comme déviant.
La transmission d’un métier et l’exercice d’un travail : limites et avantages de genre (Rome, xviie-xviiie siècle)
Authors: Groppi Angela
Published: May 2022

C’est un texte singulier et original de la grande historienne italienne Angela Groppi (1947-2020) que nous choisissons ici de publier. Tapuscrit d’une communication qu’elle avait présentée lors de la journée d’étude Femmes, droits, travail à l’époque moderne (Normandie/Europe) organisée par Anna Bellavitis le 13 mars 2015 à Rouen, il est un témoignage de tout un pan d’une recherche au long cours à la croisée de l’histoire sociale des femmes et du genre, de l’histoire des métiers et des corporations ainsi que de l’histoire du droit à la propriété et de la gestion des biens.
Jeunes Européens à Dakar et Ouagadougou. De nouvelles aventures migratoires ?
Authors: Bredeloup Sylvie
Published: May 2022

Les jeunes Européens qualifiés n’hésitent pas à envisager des scénarios d’avenir, dans lesquels les capitales d’Afrique subsaharienne tiendraient un rôle déterminant au sein de leur parcours professionnel et personnel. À partir de récits de vie réalisés à Dakar et Ouagadougou, il s’agira de documenter à la fois les imaginaires de référence, les stratégies d’insertion professionnelle et les projets de vie de jeunes Européens, les uns ayant été recrutés, comme stagiaires ou volontaires dans des structures internationales, les autres ayant négocié leur place et créé leur propre activité.
Les Français de Londres, pas tous expatriés
Authors: Le Luyer Diane
Published: May 2022

La présence internationale qu’incarnent les Français établis à l’étranger représente un atout pour la France. En filigrane des mesures déployées à leur attention, les objectifs d’influence que poursuit l’État concurrencent parfois les objectifs d’accompagnement affichés. Pensé dans une optique moderne et universaliste, le dispositif d’encadrement aborde la population établie hors de France selon une image valorisable sur laquelle capitaliser pour la poursuite d’un objectif de soft power. L’émigration française à Londres, autrefois aristocratique ou bourgeoise s’est démocratisée et la recomposition sociale de l’expatriation qui se traduit aujourd’hui dans les parcours professionnels révèle le manquement des dispositifs institutionnels à leur mission d’encadrement des citoyens.
Usages de l’espace, positionnement social et dimensions raciales : le cas des immigrés français de Salvador de Bahia (Brésil)
Authors: Sigrist Marie , Michaud Maxime
Published: May 2022

Les immigrés français établis au Brésil vivent le plus souvent dans les grandes métropoles du Sudeste. Toutefois, quelques-uns ont choisi d’immigrer à Salvador (Bahia). Porteuses d’influences afro-brésiliennes marquées, Salvador a la particularité de compter la plus grande part de population auto-identifiée noire du pays. À l’instar des autres métropoles brésiliennes, la capitale bahianaise présente aussi une urbanisation ségrégative. Dans ce contexte, il est pertinent d’interroger la situation des Français dans l’espace géographique urbain et dans l’espace socio-économique. L’étude anthropologique de leurs lieux de résidence et des usages qu’ils font des ressources urbaines donnent à voir leur position sociale et les perceptions hétérogènes qu’ils portent sur cette dernière, au regard notamment des enjeux postcoloniaux et de leur origine européenne.
Construire un système alimentaire territorial durable
Authors: Nougarèdes Brigitte , Giraud Sophie , Clément Camille , Ruault Claire , Lambert Carole , Rixen Annabel
Published: May 2022

Cet article présente une démarche de concertation territoriale portée par le conseil de développement du Pays Cœur d’Hérault visant à organiser des « États généraux de l’alimentation et de l’agriculture durable » (EGAAD). Cette démarche a pour objectif à terme de développer un système alimentaire territorialisé durable (SATD) à l’échelle du Pays, territoire regroupant 77 communes et trois intercommunalités. Le dispositif de concertation territoriale, élaboré avec une équipe de recherche (INRAe-UMR Innovation) avait pour objectif de mobiliser tous les acteurs de l’approvisionnement alimentaire local, les consommateurs, les associations citoyennes et les élus afin de construire un diagnostic partagé et d’identifier les pistes d’action concrètes pour développer le SATD et construire une gouvernance agricole et alimentaire à l’échelle du Pays. La concertation territoriale conduite sur une année, a mobilisé divers dispositifs (études diagnostics, forums citoyens, groupes de travail, restitutions publiques…). La participation a été inégale au regard du dispositif de concertation déployé. Alors que celle des professionnels de l’approvisionnement alimentaire local est restée faible, celle de la société civile et des élus a crû au cours du processus. Toutefois, cette concertation a permis de remettre l’alimentation à l’agenda politique du Pays.
A Novel Method for Total IgE Purification from Human Serum
Authors: Badloe Fariza Mishaal Saiema , De Vriese Shauni , De Bruyn Carlier Tina , Vandersichel Elise , Scheffel Jörg , Maurer Marcus , Ring Johannes , Gutermuth Jan , Kortekaas Krohn Inge
Published: May 2022

For Ab purification, high-affinity chromatography is commonly used. This technique results in high-purity Abs, but it requires highly specific knowledge and equipment. Commercial kits for purification of IgE are not available. Therefore, we established a (to our knowledge) novel method for the purification of total IgE from human serum. Sera from 19 allergic and nonallergic patients were included. After depletion of polyclonal IgG, total serum IgE was captured using anti-human IgE Abs coupled to beads, eluted from the beads, and incubated with protein G–coupled beads to increase the final purity. Purity analysis and Ab detection were performed by Western blot. Total serum IgE and purified IgE concentrations were analyzed using ELISA. To determine their functionality, primary human mast cells were sensitized with purified IgE and activated with anti-IgE or a relevant allergen. CD63+ expression and histamine release were used as readout parameters. Concentrations of purified total IgE corresponded with the levels of total serum IgE. Minor fractions of IgE remained attached to the beads, confirming an effective elution of IgE Abs. Only minimal amounts of IgG were found in the purified IgE fractions, confirming a high purity of IgE. Mast cells sensitized with purified IgE and subsequent activation with anti-IgE Ab or a relevant allergen showed increased expression of CD63+ and increased histamine release. This (to our knowledge) novel method represents a highly effective and widely accessible approach for purification of human serum IgE, which can improve the use of IgE-based in vivo and in vitro models and contribute to allergy research.
Peripheral sTREM2-Related Inflammatory Activity Alterations in Early-Stage Alzheimer’s Disease
Authors: Weber Grace E , Khrestian Maria , Tuason Elizabeth D , Shao Yvonne , Pillai Jagan , Rao Stephen , Feng Hao , Zhou Yadi , Cheng Feixiong , DeSilva Tara M , Stauffer Shaun , Leverenz James B , Bekris Lynn M
Published: May 2022

Alzheimer’s disease (AD) has been linked to multiple immune system–related genetic variants. Triggering receptor expressed on myeloid cells 2 (TREM2) genetic variants are risk factors for AD and other neurodegenerative diseases. In addition, soluble TREM2 (sTREM2) isoform is elevated in cerebrospinal fluid in the early stages of AD and is associated with slower cognitive decline in a disease stage–dependent manner. Multiple studies have reported an altered peripheral immune response in AD. However, less is known about the relationship between peripheral sTREM2 and an altered peripheral immune response in AD. The objective of this study was to explore the relationship between human plasma sTREM2 and inflammatory activity in AD. The hypothesis of this exploratory study was that sTREM2-related inflammatory activity differs by AD stage. We observed different patterns of inflammatory activity across AD stages that implicate early-stage alterations in peripheral sTREM2-related inflammatory activity in AD. Notably, fractalkine showed a significant relationship with sTREM2 across different analyses in the control groups that was lost in later AD-related stages with high levels in mild cognitive impairment. Although multiple other inflammatory factors either differed significantly between groups or were significantly correlated with sTREM2 within specific groups, three inflammatory factors (fibroblast growth factor-2, GM-CSF, and IL-1β) are notable because they exhibited both lower levels in AD, compared with mild cognitive impairment, and a change in the relationship with sTREM2. This evidence provides important support to the hypothesis that sTREM2-related inflammatory activity alterations are AD stage specific and provides critical information for therapeutic strategies focused on the immune response.
Ecological characterization of a cutaneous leishmaniasis outbreak through remotely sensed land cover changes
Authors: Andreo Verónica , Rosa Juan , Ramos Karina , Salomón O. Daniel
Published: May 2022

In this work we assessed the environmental factors associated with the spatial distribution of a cutaneous leishmaniasis (CL) outbreak during 2015-2016 in north-eastern Argentina to understand its typical or atypical eco-epidemiological pattern. We combined locations of human CL cases with relevant predictors derived from analysis of remote sensing imagery in the framework of ecological niche modelling and trained MaxEnt models with cross-validation for predictors estimated at different buffer areas relevant to CL vectors (50 and 250 m radii). To account for the timing of biological phenomena, we considered environmental changes occurring in two periods, 2014-2015 and 2015-2016. The remote sensing analysis identified land cover changes in the surroundings of CL cases, mostly related to new urbanization and flooding. The distance to such changes was the most important variable in most models. The weighted average map denoted higher suitability for CL in the outskirts of the city of Corrientes and in areas close to environmental changes. Our results point to a scenario consistent with a typical CL outbreak, i.e. changes in land use or land cover are the main triggering factor and most affected people live or work in border habitats.
Inflammatory Bowel Disease in Pregnancy
Authors: Lenin Audrin , Ninan George Abraham , Vijayaselvi Reeta , Rathore Swati , Rajan Sudha Jasmine
Published: May 2022

Inflammatory bowel disease (IBD) affects women in their reproductive years with severe disease associated with maternal morbidity and adverse fetal outcome. A retrospective chart review was conducted for all patients admitted under the departments of Medicine and Obstetrics from 2012 to 2018. The patients with IBD in pregnancy were identified. The inpatient and outpatient charts of these patients were reviewed for the clinical profile, treatment received, and outcomes. We report our experience of managing pregnant women with IBD in South India. Of the five patients, two presented with the active severe disease during pregnancy and were treated with steroids and azathioprine of whom, one developed chorioamnionitis and the other metabolic complications. All except one pregnancy required operative delivery. Pregnancy outcomes in IBD are dependent on the disease activity status at conception. Diagnosis of IBD in pregnancy is a challenge, as full-length colonoscopy and computed tomography imaging is not feasible. Chorioamnionitis is a complication associated with IBD, probably due to immunosuppressive drugs.
The Role of Ictal Brain Single Photon-Emission Tomography in Refractory Epilepsy Complementary to Magnetic Resonance Imaging and Electroencephalogram – Our Experience
Authors: Benjamin Justin , Sunny Saumya Sara , Hephzibah Julie , Mathew David , Jasper Anitha , Thomas Maya , Shanthly Nylla , Oommen Regi
Published: May 2022

Background:

Correct identification of the epileptogenic zone (EZ) is essential for surgical success for focal epilepsy. There are multiple modalities which are available for detecting the anatomical and the functional abnormalities. The purpose of this study was to determine the complementary role of ictal brain single photon-emission tomography (SPECT) in delineating the EZ in addition to electroencephalogram (EEG) and magnetic resonance imaging (MRI).

Methodology:

Clinical and diagnostic data from patients with refractory epilepsy undergoing ictal brain SPECT (IEBS), EEG, MRI between 2014 and 2019 were analyzed retrospectively. Tc99m-ethyl cysteinate dimer was administered intravenously during or within 30 s of onset of seizure activity.

Results:

Eighty-nine patients aged: Four months-32 years (median age: Eight years) were studied. The concordance of IEBS with MRI and EEG were studied. Among them, EEG was normal in 22 and abnormal in 67 (multifocal: 40, unifocal: 8, generalized: 19). MRI was normal in 36, abnormal in 26, nonspecific in 24 and not done in three patients. Of the 80 patients showing tracer uptake in IEBS, 14-multifocal uptake and 66-unifocal uptake (EEG and MRI were not showing any abnormality in 15 and 27 patients, respectively). Unifocal uptake in IEBS was concordant with EEG in 11 (16.67%) and MRI in 15 (27.72%). The concordance and nonconcordance of the results among the two imaging modalities or EEG assuming surgical site as the gold standard was noted. Twenty-two had undergone surgical removal of the EZ, 15 was conformable with MRI or IEBS.

Conclusion:

In patients with noncontributory EEG and MRI, IEBS could detect the epileptogenic focus. Therefore, depending entirely on EEG and MRI may limit its diagnosis. IEBS, MRI and EEG are complementary to each other in the detecting the epileptogenic focus.
Review of Current Evidence in Management of Oleander Poisoning
Authors: Thomas Vineeth Varghese , Newbigging Nalini , Johnson Jacob , Kalimuthu Murugabharathy , Gunasekaran Karthik , Iyadurai Ramya
Published: May 2022

India has a high incidence of poisoning, especially in the rural setting with plant-based compounds being used as a common agent. Oleander poisoning is a common shrub seen throughout the tropics including nearly all parts of India. It continues to remain an important cause for both accidental and deliberate self-harm in the community with all parts of the plant containing toxin sufficient to cause poisoning. There is enough evidence to show that oleander poisoning continues as one of the more common plant-based causes for poisoning. This review looks at the common management principles and provides an update on the currently available treatment strategies and evidence for them.