bluuebunny/crossref_metadata_2025 huggingface dataset:
Mathematical model for calculating the output parameters of a stationary plasma thruster
Authors: Gavrikov Mikhail Borisovich , Tayurskiy Aleksei Aleksandrovich
Published: June 2024

The mathematical model allowing to calculate the output parameters of plasma in SPT is considered, bypassing the calculation of the main plasma processes in SPT. It turns out that under certain conditions – setting the output parameters along the SPT axis and plasma incompressibility, this is possible. The determining factors underlying the proposed approach are the two-fluid nature of plasma, including full consideration of the electron inertia and dissipative processes – magnetic and hydrodynamic viscosities of electrons and ions, thermal conductivity of plasma and temperature relaxation. Mathematically, the calculation of the output diagrams is reduced to solving a boundary value problem for a certain linear system of ODE of the 8th order with variable coefficients on the segment. The paper proposes two methods of successive approximations for the numerical solution of the obtained boundary value problem. The convergence of successive approximations, the uniqueness theorem are proven and the matrix Green function is constructed. The results of calculations are presented, demonstrating the operability of the mathematical model.
HUBUNGAN FLEKSIBILITAS KOGNITIF DAN EFIKASI DIRI DENGAN KOMPETENSI KEWIRAUSAHAAN MAHASISWA CALON GURU PENDIDIKAN TEKNIK FKIP UNS
Authors: Handayani Sri , Akhyar Muhammad , Widiastuti Indah
Published: June 2024

This study aims to determine whether there is a relationship between cognitive flexibility and self-efficacy with the entrepreneurial competence of prospective teacher students, namely a case study of Vocational Engineering Education students. This research was conducted using a quantitative approach, cognitive flexibility and self-efficacy as independent variables, entrepreneurial competence as the dependent variable. The population in this study were active students of the Sebelas Maret University majoring Vocational Engineering Education class 2018-2021. The total population is 921 students who consist of 315 students of Mechanical Engineering Education Study Program, Building Engineering Education as many as 297 students, and Information and Computer Engineering Education as many as 309 students. The researcher used the Stratified Random Sampling method in determining the sample size. The technique used to collect data using a Likert scale instrument. During the data collection process, the Sub-competences of Entrepreneurial Competency and Underlying Behavioral Indicators were used to measure the entrepreneurial competencies of prospective teacher students, Cognitive Flexibility Inventory (CFI) to measure the level of cognitive flexibility, and the General Self-Efficacy Scale (GSE) to measure the level of self-efficacy. The analytical method used is multiple linear regression analysis. The results of this study indicate that there is a positive relationship between cognitive flexibility and self-efficacy with entrepreneurial competence (R=.736, R2=.542, p=.000). Therefore, it can be said that the entrepreneurial competence of prospective teacher students can be improved through cognitive flexibility and self-efficacy beliefs.
PENGEMBANGAN E-MODUL PRAKTIKUM KELISTRIKAN OTOMOTIF BERBASIS SELF DIRECTED LEARNING PADA PROGRAM STUDI PENDIDIKAN TEKNIK MESIN UNS
Authors: Pangestu Agrippina Gian , Ranto Ranto , Rohman Ngatou
Published: June 2024

Technology has created numerous benefits in various aspects of life, including education. Teachers and students should integrate technology into their learning plans to ensure effective teaching and learning. The use of technology in education can inspire students to pursue new interests and motivate them to engage in learning activities that enhance their perspectives. The role of an instructor in a student's education is crucial. Self-directed learning (SDL) is an instructional process that requires students to identify their own learning needs, provide resources, and practice learning techniques. By using the right methods and situations in teaching, students can develop their own skills and enhance their learning experience. This study aims to improve the effectiveness of e-module practical on the otomotif kelistrikan in the Mesin Technical Education program.

The study on the development of an e-module for otomological pedagogy found that the validity of the e-module met good results with validity scores of 84.4% (very feasible) for material, 85% (very feasible) for media, 75% (feasible) for language, and 83,3% very (feasible) for data from student responses. Critics and respondents also deemed that improvements are needed for the e-module. The results were based on feedback from the committee of otomologists who provided some suggestions about the electronic pedagogical pedagogy module in terms of quality and safety, indicating that improvements are still needed for this module. The e-module will be distributed through the Mesin Technical Education Program at the University of Surakarta.
Keywords: development, e-modules, self directed learning
THE EFFECT OF MANAGEMENT CHARACTERISTICS ON EARNINGS MANAGEMENT THROUGH PERCEIVED AMBIGUITY IN ACCOUNTING STANDARDS
Authors:   Gadjah Mada University, Suci Patricia Paramitha , Fajar Stella Marissa Permata ,   Gadjah Mada University
Published: June 2024

We investigated the influence of management characteristics, specifically narcissism, impulsivity, construal mindset, and Machiavellianism, on perceived ambiguity toward accounting standards and the impact of perceived ambiguity toward accounting standards on earnings management tendencies. We surveyed 116 respondents from undergraduate, master's, and doctoral programs at various universities in Indonesia. We found that construal mindset, impulsivity, and Machiavellianism positively were related to perceived ambiguity toward accounting standards. Perceived ambiguity toward accounting standards has also been shown to affect earnings management tendencies positively. However, we did not find that narcissism was related to perceived ambiguity toward accounting standards. Additionally, we did not find that narcissism and construal mindset were positively related to earnings management tendencies when mediated by perceived ambiguity toward accounting standards. This research aims to provide a deeper understanding of how management characteristics influence earnings management practices.
IMPLEMENTATION OF THE 2013 CURRICULUM IN IMPROVING THE QUALITY OF EDUCATION AT VILLANOVA MIDDLE SCHOOL, WEST PAPUA
Authors: Teguh Terianung D.S  , Nugraha Adhi Setiawan  , Winda Sundari  , Ema Amalia  , Natalis Michael Giovanni  , Adi Wulandari
Published: June 2024

This research raises the topic of implementating the 2013 curriculum in improving the quality of education at Villanova Manokwari Middle School, West Papua. The aim is to find out whether the implementation of the 2013 curriculum can improve the quality of education at Villanova Manokwari Middle school. This research was conducted at Villanova Manokwari Catholic Middle School in November-December 2023 using a literature study approach with qualitative methods. This results show that Villanova Catholic Middle School has implemented the 2013 curriculum with a scientific approach. The main target is the development of student competence in the domains of attitudes, skills and knowledge. This can be seen in the teaching design created by teachers at school by adapting all teaching programs to follow the provisions of the 2013 curriculum which contain 4 competency domains, namely: Spiritual attitude competency (KI-I), social attitude competency (KI-2), knowledge competency (KI-3), and skillscompetency (KI-4). Based on the competency characteristics that are the reference for the 2013 curriculum, it is known that the implementation of the 2013 curriculum in improving the quality of education places character education within the framework of the the dynamics and dialectics of the process of individual formation. This competency development is carried out through integrated thematic education at Villanova Catholic Middle School.
Keywords: Implementation, 2013 curriculum.
Honorary Teachers Peformence : Academic Supervision and Organizational Culture in Public Junior High School
Authors: Yuliarti Dinny Puspita , Sari Eliana , Fuad Nurhattati
Published: June 2024

Teacher performance is one of the important elements in the achievement of quality at school because the teacher is the main component in the educational system that can affect the success of educational goals. Many factors can affect the performance of teachers, among them are seen from the implementation of supervision academic and organizational culture applied in the school environment. This research aims to determine the performance of honorary teachers who are influenced by the academic supervision and culture of organizations in the subdistrict of South Cikarang. The researchers took samples using the Purposive Sampling method of 134 honorary junior high school teachers in the subdistrict of south Cikarang, Bekasi. Data was analyzed using path analysis techniques, to test the hypothesis of the academic supervision variable (X1) on the performance of teachers (Y) and the organizational culture (X2) on the teacher performance (Y), with SPSS 25. Results of the calculation of the path analysis of X1 and Y, obtained t-count = 2,893 > ttable (α=0.05) = 1,978, the result that the variable of academic supervision influences teacher performance. Then the path analysis of X2 and Y, obtained tcount= 2,962 > ttable (α=0.05) = 1,978, showing that the variables of the cultural organization influence teacher performance.
Evaluation of Pesantren Financial Management Through the Implementation of the Simkeu Application at Api Syubbanul Wathon Tegalrejo Secang Islamic Boarding School
Authors: Khilmi Nala , Siswanto  , Laili Syarifa
Published: June 2024

This study aims to evaluate the financial management of API Syubbanul Wathon Tegalrejo Secang Islamic Boarding School through the implementation of the Financial Management Information System (SIMKEU) application. The background of this research is that the challenges in financial recording that are still done manually, prone to errors, and take a long time. The research method used uses a case study approach with a qualitative approach. Data was collected through in-depth interviews with pesantren leaders and administrative staff, direct observation of the financial management
process, and analysis of documents related to pesantren finance. The research was carried out at API Syubbanul Wathon Tegalrejo Secang Islamic Boarding School over a certain period. The results showed that the implementation of SIMKEU succeeded in increasing efficiency in recording and financial management by reducing the time required for the transaction recording process and improving the accuracy of financial statements. However, the study also identified several challenges, such as issues with information and communication technology infrastructure that need to be improvement, and the initial adaptation phase requiring extra time and effort from pesantren staff. Based on the study’s results, it is recommended to enhance information and communication technology infrastructure, and increase training for pesantren staff to maximize the benefits of SIMKEU implementation in the future. In conclusion, the implementation of SIMKEU at API Syubbanul Wathon Tegalrejo Secang Islamic Boarding School has made a significant contribution in improving the efficiency and transparency of Islamic boarding school financial management. This study provides practical guidance for other pesantren that want to adopt similar technologies in an effort to improve financial management effectively and efficiently.
The Influence of Emotional Intelligence on Job Satisfaction Mediated by Self-Efficacy
Authors: Herdiman  , Tirtoprojo Susanto
Published: June 2024

This research investigates the influence of emotional intelligence on job satisfaction which is mediated by self-efficacy. This research was conducted on state elementary school teachers in Nanga Wera Village, Wera District, Bima Regency. Data was collected using an online survey method. The respondents in this investigation were educators who taught at state primary educational institutions in Nanga Wera village, Wera subdistrict, Bima Regency. The number of respondents to this study was 52 people and were identified using an online questionnaire. Data analysis was carried out using a statistical regression approach using SmartPLS software. The research results show that there is a significant positive influence between teacher emotional intelligence and job satisfaction, and self-efficacy has a significant mediating influence on how job satisfaction and emotional intelligence are related.
Development Of Picture Card Media Based On Science Literacy On Ecosystem Materials
Authors: Aryandari Mita , Sari Prima Mutia
Published: June 2024

It is known that the science literacy score in Indonesia in PISA (Programe for International Student Assement) which is carried out in 2022 is up 6 positions compared to 2018. However, the score dropped by 13 points. This needs to be improved the quality of education in Indonesia, one of the factors that influence it is the lack of innovation in the use of science literacy-based learning media. The purpose of this study was to determine the characteristics, feasibility, and response to picture card media based on science literacy in grade V elementary school ecosystem materials. The research method used is R&D with the ADDIE model, namely analysis, design, development, implementation, and evaluation. To determine the feasibility of the media, a validation test was carried out by material experts and media experts using validation sheets. From the expert validation test, the material obtained a percentage of 100% with a very decent category. The results of the media test obtained a percentage of 100% with a very decent category. To determine the media response, respondents were filled out questionnaires by teachers and students. The results of students' responses to the media obtained a percentage of 93% in the very good category. While the results of the teacher's response obtained a percentage of 95% with a very good category. This study found that the picture card media based on science literacy ecosystem material is very feasible and very good to be used as a learning medium that can be an idea and motivation for teachers to make learning media innovations. In addition, it can help students in the learning process and increase knowledge related to science literacy skills. Further research can develop picture card media with other subjects and materials.
Implementation of Merdeka Belajar Kampus Merdeka Program in Improving the Quality of Education in Indonesia
Authors: Trianung Teguh , Gumilang Syifa Retno , Umair Zahid , Adilah Khadijah , Sawal Muhamad Ramadan , Kosam Fifty Ayu Lestari
Published: June 2024

The existence of the Ministry of Education and Culture policy related to Merdeka Belajar Kampus Merdeka Program (MBKM) is the right effort in creating a generation that has soft skills and hard skills, and is qualified in aspects of leadership and personality. The MBKM program was launched in 2020 as a new breakthrough for the Ministry of Education and Culture to increase the flexibility of Indonesia's higher education system. MBKM provides greater autonomy for universities and students in designing study programs through student exchange schemes, partner internships, to research or field projects.MBKM is one of the policies of the Minister of Education and Culture, Nadiem Makariem. One of the programs of this MBKM policy is the Right to Study Three Semesters Outside the Study Program. The focus of this study is to analyze the implementation of MBKM comprehensively in improving the quality of education in Indonesia, so that it can be useful for formulating strategies for improvement and development of MBKM policies in the future. The research method used is a literature study of the material or research that has been done. From the results of the study, it can be seen that the implementation of MBKM helps students in their self-development, in addition, additional skills and student academic achievement also increase.
EXPLORING Exploring the Influence of Brand Image and Education Costs on Parents' Decisions in Choosing a School: The Mediating Impact of Word of Mouth (WoM)
Authors: Khurin Najwa Khurin
Published: June 2024

Word of Mouth (WoM) tends to be more trusted than direct promotion from the school. Parents tend to trust other people's real exp=eriences in choosing a school, which can strengthen a school's positive brand image. Through WoM, parents can get more in-depth information about various aspects of the school, including the quality of education, facilities, curriculum, and learning atmosphere. This research aims to investigate the mediating role of WoM in influencing brand image and educational costs on parents' decisions in choosing a school. Purposive sampling was used to determine research respondents totaling 43 parents at SMP Ma`arif 2 Ponorogo. Data were analyzed using path analysis with the PLS-SEM method. The research results show that WoM acts as a mediator which is insignificant on the brand image (β=0.094; ρ=0.101), but significant on the cost of education and parents' decisions in choosing a school (β=0.388; ρ=0.005). Apart from that, WoM also directly influences parents' decisions (β=0.540; ρ=0.000). These findings highlight the importance of recommendations and reviews from other parents in shaping parents' perceptions of a school, which impacts their decisions in choosing a school for their children. The practical implications of this research are that schools can improve their brand image and adjust their tuition fees to be more attractive to parents, while also strengthening WOM marketing strategies to improve parents' school choice decisions.
The Influence of Entrepreneurship Education on the Competence of Start-Up Ventures in Empowering Nascent Makeup Artists
Authors: Lestari Retno , Saripah Lip , Suryadi Ace , Sardin Sardin
Published: June 2024

This research aims to analyze the influence of entrepreneurship education on startup business competencies through the empowerment of prospective makeup artists. The study employs a quantitative approach with structural equation model analysis techniques using the AMOS application. The population of this study comprises alumni of the Entrepreneurial Skills Education Program (PKW) from Training and Course Institutes (LKP) between 2016 and 2018 in West Java. The sampling technique used is random sampling. Data were obtained through a questionnaire completed by 136 respondents. The results of the study indicate that entrepreneurship education does not have a significant effect on startup business competencies through the empowerment of prospective makeup artists. However, entrepreneurship education significantly influences two variables: startup business competencies (48.6%) and the empowerment of prospective makeup artists (89.1%). The study reveals the reasons for the low achievement of the PKW Program's success based on two indicators. Indicator II states that at least 75% of graduates should be able to start a business, and Indicator III specifies that at least 30% of those who start a business should earn an income equivalent to the local minimum wage within six months. The low success rate of the PKW Program in this study is explained by the limited skills of the mentors and the lack of reflection activities during the mentoring process. This research highlights the urgent need for effective mentors when prospective bridal makeup artists design and launch their startups. Mentors play a critical role in providing business insights, market advice, and market validation. Therefore, it is necessary to improve the quality of mentors and establish qualification standards for startup business mentors.
Halk Hikayelerinde Matbuat Umum Müdürlüğü’nün Aldığı Kararların Uygulanmasına Bir Örnek: Arzu ile Kamber Hikayesi
Authors: Akbaba Mehmet Fatih
Published: July 2024

Halk hikâyeleri, bir sözlü kültür ürünü olarak edebî ve toplumsal hayata girmiş daha sonra yazılı olarak geleneğini devam ettirmektedir. Her toplumun her kültürün kendi birikimin ürünü olan halk hikâyeleri, Türk kültüründe ozanlık geleneği ile başlamış daha sonra Osmanlı’da âşıklık geleneğinin unsuru olarak devam edip yazılı eserler aracılığıyla günümüze kadar ulaşmıştır. Elbette ki, halk edebiyatı ürünlerinin oluşumunda toplumların kendi birikimi kadar bu hikâyelere yükledikleri anlam da etkilidir. Halk hikâyeleri, toplumların realizmle ilişkisinin arttığı bir dönemde ortaya çıktı.

Bu çalışmada öncellik olarak, halk hikâyesi kavramını yeniden uzun uzadıya açıklamak değil, Türkiye sahasındaki kaynaklarda yer alan, aynı başlığı taşıyan “Arzu ile Kamber” hikâyesinin 1908 yılı öncesi taşbasması nüshasıyla 1928 sonrası yeni harfle (Latin harfleriyle) yeniden ortaya konan nüshasını, 1937 yılında Matbuat Umum Müdürlüğü’nün almış olduğu kararlar doğrultusunda incelemek ve bu anlamda değerlendirme yapmaktır. Bu değerlendirme sonunda, Matbuat Umum Müdürlüğü’nün kendi kararları doğrultusunda başlattığı girişimlerinin ne anlama geldiğini ve bu anlamı ne kadar başarıya taşıdığını ortaya koymaya çalışılmaktadır.
La enseñanza del derecho constitucional como una oportunidad para abordar la diversidad sexual y de género en la universidad
Authors: Siverio Luis Sergio
Published: July 2024

El abordaje de la atención a la diversidad sexual y de género sigue siendo una asignatura pendiente en la docencia universitaria. En el presente trabajo sostenemos que la docencia del Derecho Constitucional es una oportunidad idónea para incorporar la perspectiva de respeto a la diversidad sexual y de género en el ámbito universitario, lo que cuenta con una cobertura jurídica sólida y la existencia de necesidades más que justificadas para afrontar este reto pendiente.Además, se incorporan algunas propuestas metodológicas para poder materializar este reto, tanto desde los órganos de gobierno de las universidades, como desde la docencia universitaria en general y del Derecho Constitucional en particular.
PITEVNÍ PROTOKOLY ZACHYCUJÍCÍ DOPRAVNÍ ÚRAZY NA ÚZEMÍ PRAHY A OKOLÍ V LETECH 1918–1968
Authors: Šimáková Eva
Published: July 2024

This paper is based on analysis of autopsy protocols from the Czech capital Prague between 1918 and 1968. The protocols were produced by the staff of institutes of forensic pathology (before 1939 there were two such institutes, later only one). Surviving collection of protocols from that period consists of 59 413 items, which likely represent a complete set of postmortem examination done in Prague. This paper will focus on protocols related to traffic accidents which will be analysed according to several categories including gender, religion, age, type of vehicle involved etc.
Austria's Institutionalized Discriminatory Policies: A Historical Study on Anti-Semitic and Anti-Muslim Phenomena
Authors: Nurasih Wiji
Published: July 2024

Racism constitutes a serious social issue in Austria. This phenomenon has garnered significant attention from activists, leading to discussions and the formation of numerous organizations dedicated to combating and addressing racism. However, despite decades of anti-racist discourse and efforts in Austria, the issue persists. Reports from anti-racist organizations indicate that incidents of racism remain prevalent to this day. Therefore, it is intriguing to investigate why racism has endured as a dynamic phenomenon in Austria. This article seeks to discuss how politics in Austria institutionalized racism, rooted in a lengthy historical context specifically, racism against the Jewish community (antisemitism) and racism against Muslims. The data were obtained through reviewing previous research findings and reports from anti-racism organizations. Descriptive analysis was employed to provide a detailed explanation of the context within a framework of power relations theory. The study reveals that the ideology
inherited from Nazism, which encompasses concepts such as Lebensraum (living space) and the marginalization of specific groups, continues to influence Austrian politics, albeit narrated differently through political campaigns and discriminatory policies. This ideological influence permeates the public sphere, serving as a crucial factor in the unresolved nature of racism in contemporary Austria. Furthermore, the research identifies a shift in political tendencies over time, transitioning from an emphasis on anti-Semitism to Government policies and political campaigns in Austria constitute significant supporting factors influencing racist actions against Muslims in the daily life of Austrian society. wards anti-Muslim racism. Through the perspective of power relations government policies and political campaigns in Austria constitute significant supporting factors influencing racist actions in the daily life of Austrian society. For example, Dokustelle (the Center for Documentation and Counseling on Anti-Muslim Racism in Austria) identified over a thousand cases of racism against Muslims in 2022.
Nadzoriyatu Khalqu al-Insan fi al-Kitab al-Muqoddas: Naqdu ‘ala Nadzariyatu al-Tathowwur li Charles Darwin
Authors: Damayanti Retno , Awaludin Asep
Published: July 2024

This article explores the fundamental differences between these theological and scientific views through analysis of the text of the Bible and Darwin's theory of evolution which aims to explain the definition of human creation and the theory of evolution and analyze the theory using verses in the Bible. To complete this writing, the researcher used the descriptive-critical analysis method to examine and criticize the theory using a naturalist worldview approach to the ideas presented by Darwin. The result is that Charles Darwin's theory of evolution becomes a new paradigm regarding human origins which denies divinity in its creation. Darwin's theory of evolution is a scientific concept which states that living species experience development through the process of natural selection. In the Book of Genesis it explains that humans were created by God, Adam was formed from the dust of the ground and breathed the breath of life into his nose and created Eve from Adam's rib, this shows that humans were created directly by God and are considered special among other creations.
The Brucella effector protein BspF crotonylates TRIM38 to inhibit NF-κB and MAPK signaling pathway.
Authors: Zhu Jinying , Wu Sijiao , Xing Yukai , Li Yuzhuo , Wang Yuqi , Gao Jingbo , Yu Ze , Li Ang , Zhang Huan , Liu Jinling , Chen Xiaoyue , Chen Zeliang
Published: July 2024

Brucellosis is caused by Brucella, which is a highly prevalent intracellular parasite. Type IV secretion system(T4SS) is an important virulence factor of Brucella. T4SS secretes 16 effector proteins, which affect the intracellular transport of Brucella-containing vacuole and regulate the host immune response, helping Brucella to survive and replicate in host cells. In our previous crotonylation proteomics data of HEK-293T cell proteintriggered by BspF, we found BspF crotonylated on TRIM38, which is an important modulator in the pathways of inflammation, and the crotonylation site is K142. Therefore, it is speculated that BspF may be involved in the regulation of host inflammatory response during Brucella infection. In this study, we found BspF-mediated TRIM38K142 crotonylation promotes the ubiquitination of Tumor necrosis factor receptor (TNFR)-associated factor 6 (TRAF6), leading to the degradation of TRAF6, thereby inhibiting the transduction of NF-κB, p38 MAPK and JNK MAPK signaling pathways and inhibits the secretion of pro-inflammatory factors IL-1β, IL-6 and IL-8, which finally helps Brucella to promote intracellular survival. This study provides a new theoretical basis for Brucella to achieve intracellular survival by regulating host innate immunity through T4SS, and provides an important reference for the study of non-histone crotonylation.
Measuring the impact of the African Continental Free Trade Area (AfCFTA) on intra-regional intermediate exports in Africa: A matching approach
Authors: ouakil hicham , OUAZZANI HICHAM EL , MOUSTABCHIR Abdelhamid
Published: July 2024

This study assesses the impact of the implementation of the African Continental Free Trade Area (AfCFTA) on the proportion of intra-regional intermediate exports in Africa. We utilized data from the Initiative for Regional Integration in Africa (IIRA) for the year 2019 and employed a matching method with Caliper. Our findings indicate that the signing of the AfCFTA leads to an average decrease of 0.02374 in the share of intra-regional intermediate exports. However, this relationship is not statistically significant at the 5% level. These results are in contrast with the predictions of the International Monetary Fund (2020) and the findings of other studies. The discrepancy may be attributed to various factors, including the level of implementation of the AfCFTA and the specific reforms needed to maximize its potential long-term benefits, which are areas that warrant further investigation.
JEL classification : F13, F15, O55
The analysis of high-risk factors and clinical characteristics in patients with main pulmonary artery thromboembolism
Authors: Feng Wanjie , He Xing , Fang Siyu , Tang Jialong , Tian Renping , Guo Lu
Published: July 2024

Objective: Main pulmonary artery thromboembolism (MPATE), a subtype of pulmonary thromboembolism (PTE), is characterized by acute onset and high mortality rate. Currently, less is known about the early diagnosis of MPATE. This study aimed to investigate the clinical characteristics and strategies of MPATE, exploring the predictive factors of MPATE.
Methods: Patients with PTE diagnosed by computed tomographic pulmonary angiography (CTPA) were retrospectively included between May 2012 to May 2022 at Sichuan Provincial People's Hospital. Based on imaging characteristics, patients were divided into the MPATE group and Non-MPATE group. The clinical features, treatment strategies, and prognosis were compared between two groups, and high-risk factors in MPATE group were analyzed by multiple logistic regression.
Results: 302 patients with PTE were enrolled, including 142 in MPATE group and 160 in Non-MPATE group. Dyspnea was the most common symptom in both groups, but the proportion of dyspnea was higher in MPATE group (P< 0.05).
Compared with Non-MPATE group, the left ventricular ejection fraction (LVEF), diastolic blood pressure, troponin I (TnI) level, and plasma D-dimer (D-D) level in MPATE group were higher at early admission (P < 0.05). Besides, the MPATE group had a higher proprotion of patients with chronic obstructive pulmonary disease (COPD) and deep vein thrombosis (DVT)(P< 0.05), and the number of patients at moderate-high risk in MPATE group was more than in Non-MPATE group(P< 0.05). The multiple logistic regression analysis showed that COPD (OR= 6.620, 95%CI: 1.825-24.015), dyspnea (OR= 2.300, 95%CI: 1.032-5.124), diastolic blood pressure (OR= 1.031, 95%CI: 1.006-1.057), DVT (OR= 2.330, 95%CI: 1.043-5.209), and LVEF (OR= 1.053, 95%CI: 1.006-1.102) were considered as risk factors of MPATE. In MPATE group, there was a negative correlation between EF and high risk (r= -0.187) or moderate-high risk (r= -0.151), but a positive correlation with low risk (r= 0.181) (P<0.01).
Conclusion: Compared with non-MPATE group, MPATE group were more likely to experience dyspnea, as well as higher levels of diastolic blood pressure and LVEF. Patients with MPATE was also prone to co-occur with comorbidities such as DVT and COPD. These results provided further understanding of MPATE.
Dietary Intake and Associated Factors Among Elderly Persons Receiving Social Assistance Grant for Empowerment (SAGE) in Northern Uganda
Authors: Omoko Jasper
Published: June 2024

Background: The government of Uganda introduced a social assistance grant for empowerment (SAGE) programme specifically targeting elderly people with the aim of improving their livelihoods and nutrition. However, its contribution to nutrient intake is not known because the objective of this study was to determine dietary intake and associated factors among elderly individuals residing in rural areas of northern Uganda.
Method: Using a cross-sectional survey design, 395 elderly individuals aged 65 years and above were sampled purposively. Validated Individual Dietary Diversity (IDDS) and 24-hour dietary recall questionnaires were used to obtain information on dietary quality and nutrient intake adequacy, respectively, as well as demographic characteristics. Descriptive and inferential statistics were computed using the Statistical Package for Social Sciences (SPSS) version 20.
Results. Although the SAGE beneficiaries generally had an improved mean micronutrient intake adequacy ratio (MAR) of 0.61±0.21, there were no statistically significant differences between their MARs and those of the non-SAGE beneficiaries, i.e., 0.58±0.23. Generally, the mean IDDS of this studied population was 5.9±1.6 food groups out of 12 food groups. The consumption of only sugary and sweet foods differed significantly between SAGE beneficiaries and non-SAGE individuals (p<0.05). The results of the general linear model regression showed that only district (β = 0.108, p=0.009) significantly determined the MAR among non-SAGE beneficiaries, while income (β = -0.120, p=0.000) and household size (β = 0.078, p = 0.044) determined the MAR among SAGE beneficiaries. The Poisson regression results indicated that the marital status (β = -0.157, p=0.003), district (β = 0.129, p=0.009) and business status (β = -0.127, p=0.019) significantly determined the IDDS (DQ) of non-SAGE beneficiaries, while education (β = -0.082, p=0.030) determined the DQ among SAGE beneficiaries. Therefore, DQ and NIA do not significantly vary among SAGE and non-SAGE beneficiaries.
Conclusion: Income above 200,000 Ugandan shillings and nutrition education could significantly improve nutrient intake among beneficiaries. The government of Uganda should therefore implement nutrition education during social gatherings, in local health centres and during SAGE distribution to cater to proper food choices, preparation and a good balanced diet.
Using Storytelling to Boost Immunization Awareness: A Pre-Post Study in a Malaysian Primary School
Authors: Othman Nur Sabrina , Bakaruddin Syafi’ah , Noordin Zakiah Mohd , Karuppannan Mahmathi
Published: July 2024

Vaccine hesitancy has led to a decline in immunization rates worldwide, posing a threat to herd immunity. Leveraging storytelling's appeal, a pictorial storybook was designed to improve children's vaccine knowledge. This study evaluated the effectiveness of the storybook in improving vaccine knowledge among children aged 8-9 years. The study employed a one-group pre-test-post-test experimental design. The survey questions were divided into two sections: demographic data and vaccine knowledge consisting of eight questions developed from the content of the storybook. A total of seven classes were randomly selected, and each child read the book with the researcher. The researcher facilitated the survey, ensuring that the participants were not guided towards specific answers. The pre- and post-test data was analysed using the Wilcoxon Signed Rank Test in SPSS version 27.0. The mean score improved from 4.43 to 6.25, and the median score increased from 5.00 to 6.00 showing a significant increase in children's knowledge about vaccines after the intervention. The proportion of children with low vaccine knowledge decreased from 49.1% before the intervention to 6.4% after the intervention. Meanwhile, the percentage of children with high vaccine knowledge increased from 6.7% to 41.2%. The Wilcoxon Signed Rank Test confirmed the statistical significance (p < 0.001) of these findings. The pictorial storybook proved to be an effective tool for enhancing children's vaccine knowledge, validating the use of age-appropriate storytelling in health education. This approach can help address vaccine hesitancy, promote early vaccine literacy, and contribute to improved vaccination rates and better public health outcomes.
A Multiscale Attention Network for the Classification of Lightning Safety Risk Warnings
Authors: Luo Zhiyong , Yin Qiyuan , Xia Min , Li Xiang
Published: July 2024

In order to meet practical business application requirements, this study considered the physical characteristics of lightning, combined with the risk of lightning disasters and disaster responses, to develop a precise classification model for lightning safety risk warnings at target points based on the the multi-scale attention residual network. By analyzing 1404 sets of thunderstorm data from four warning levels in Guangdong region, we trained convolutional neural networks, support vector machines, random forests, extreme gradient enhancement networks, as well as the multi-scale attention residual network (MSA) constructed by our research institute. The results showed that the multi-scale attention residual network has interpretability for lightning safety risk warning, (1) This model proposes an attention mechanism to fuse different features, obtain the importance distribution of different features, and increase the number of neural network layers to extract deeper features. (2) This lightning safety risk warning model is the most reliable among the five models, with an accuracy rate of 93%. (3) For the four-level classification model, it was found that the accuracy of the lightning safety risk warning models based on the MSA remained above 70% (77%), and also achieved the highest recall, lowest standard deviation, and lowest log loss.
Operando X-ray characterization platform to unravel catalyst degradation under accelerated stress testing in CO2 electrolysis
Authors: Drnec Jakub , Xu Qiucheng , Zeledón José Zamora , Joensen Bjørt Óladóttir , Trotochaud Lena , Sartori Andrea , Kaas Lau , Moss Asger , Mirolo Marta , Mairena Luis , Huynh Sylvia , Garg Sahil , Helveg Stig , Chorkendorff Ib , Zhao Shuai , Seger Brian
Published: July 2024

Membrane-electrode assembly (MEA)-based CO2 electrolysis technology has a promising future to realize the industrial-scale production of diverse value-added chemical commodities. One crucial metric for CO2 electrolysis is stability. However, comprehensive but distinguishable degradation mechanisms of catalyst and electrode in the MEA are still missing when assembled in the electrolyzer. Herein, a customized operando synchrotron X-ray characterization platform was first established to track the time- and space-resolved evolution of ions and water movements, crystal structure, and particle size of the catalyst in the entire MEA. Based on the model catalysts of Au and Ag, we reveal that the crystalline phase stability of catalyst and catalyst-substrate interaction together determine cathode durability. The D-ratio (i.e., diameter ratio achieved from a deep analysis of small/wide angle X-ray scattering) is a good descriptor to evaluate the structure stability of catalyst on electrode. Au catalysts with a more stable crystal structure and strong catalyst-substrate interaction possess a smaller D-ratio change as well as a better durability under a pulse-driven accelerated stress test in contrast to Ag catalysts, which degrade due to agglomeration and Ostwald ripening. This work demonstrates the broad capability of the newly developed operando X-ray characterization platform to unveil catalyst and electrode degradation in MEA-based devices.
Benchmarking and Automating the Biotinylation Proteomics Workflow
Authors: Hao Ling , Li Haorong , Smeriglio Noah , Ni Jiawei , Wang Yan , Sekine Shiori
Published: July 2024

Protein biotinylation has been widely used in biotechnology with various labeling and enrichment strategies. However, different enrichment strategies have not been systematically evaluated due to the lack of a benchmarking model for fair comparison. Most biotinylation proteomics workflows suffer from lengthy experimental steps, non-specific bindings, limited throughput, and experimental variability. To address these challenges, we designed a two-proteome model, where biotinylated yeast proteins were spiked in unlabeled human proteins, allowing us to distinguish true enrichment from non-specific bindings. Using this benchmarking model, we compared common biotinylation proteomics methods and provided practical selection guidelines. We significantly optimized and shortened sample preparation from 3 days to 9 hours, enabling fully-automated 96-well plate sample processing. Next, we applied this optimized and automated workflow for proximity labeling to investigate the intricate interplay between mitochondria and lysosomes in living cells under both healthy state and mitochondrial damage. Our results suggested a time-dependent proteome remodeling and dynamic translocation within mitochondria and between mitochondria and lysosomes upon mitochondrial damage. This newly established benchmarking model and the fully-automated 9-hour workflow can be readily applied to the broad fields of protein biotinylation to study protein interaction and organelle dynamics.
Computational demonstration of multiple DNA damages produced by the radiolytic chemical species in an aqueous DNA solution
Authors: Kai Takeshi , Toigawa Tomohiro , Matsuya Yusuke , Hirata Yuho , Tsuchida Hidetsugu , Ito Yuma , Yokoya Akinari
Published: July 2024

Multiple DNA damage resulting from the single ionisation of a water molecule is the most fundamental process of the initial step of radiobiological effects. The critical size and the chemical lesion types constituting the damage site have not been fully elucidated. We challenged this long-term issue by developing a dynamic Monte Carlo code for the chemical process. The reaction probabilities and the spatial distribution of lesions were theoretically solved as a function of the spur radius and distance between DNA and the initial ionisation position. The results showed that a hydroxyl radical and a hydrated electron from a single spur can concomitantly react within a 10 base pairs DNA to induce a multiple DNA damage site comprising a DNA single-strand break and reductive nucleobase damage; however, the reaction probability is 0.4% or less. Once this combination arises, it strongly compromises the activity of nucleobase excision repair enzymes. The efficiency is comparable to that of DNA double-strand breaks, which have been thought to be a significant cause of cell death. However, a single-spur reaction could be a source of damaged nucleobase misrepair, leading to point mutations in the genome.
Understanding Thin Cambered Airfoils and their Solar Aircraft Applications
Authors: Suppes Galen J. , Suppes Adam B.
Published: July 2024

Modified thin cambered solar panels may be used as wing sections, thereby enabling high solar panel productivity in ultralight designs to directly displace battery and fuel costs. Computational studies were performed to better understand limits in performance and how to achieve high lift-drag ratios (L/D). Induced thrust at leading sections of thin cambered airfoils are key to creating high L/D in 2D airfoils; however, the dynamics significantly change when loss of lift pressures across side edges of low aspect ratio (AR) designs diminish the propagation of trailing-section lift-generating sources forward. Preliminary studies on use of fences, distributed propulsion, and novel airframe designs were investigated to overcome these challenges of using thin cambered wings. Wing designs previously dismissed as having inadequate lift coefficients are now prime candidates for solar aircraft where bifacial solar modules can be greater than 2X the productivity of solar panels on Earth’s surface.
Stealth Gamification in der selbstgesteuerten non-formalen Erwachsenenbildung
Authors: Barth René
Published: July 2024

Der digitale Wandel fördert das Interesse an Online-Lernplattformen, wirft jedoch Fragen bezüglich der Gestaltung motivierender altersgerechter Angebote auf. Gamification, die Integration von Spielelementen und -mechanismen unter anderem in Lernkontexten, bietet Potenzial zur Steigerung von Motivation und mithin Nutzungsengagement und Lernleistung. Die Effektivität von Gamification hängt dabei stark von der Akzeptanz durch die Lernenden ab, insbesondere bei Erwachsenen, bei denen eine subtile Implementierung nötig sein kann, um den bis in die Gegenwart sozialhistorisch nachvollziehbaren Gegensatz zwischen Spiel und Ernst zu umgehen. Die Herausforderung liegt darin, spielerische Aspekte so zu integrieren, dass sie, um Ablehnung zu vermeiden, die Lernmotivation ohne offensichtliche Spielmechanismen fördern. Forschungsergebnisse deuten darauf hin, dass erwachsene Lernende spielerischen Inhalten in ernsten Kontexten häufig kritisch gegenüberstehen, was die Wirkung von Gamification einschränken oder verhindern kann. Eine erfolgreiche Anwendung von Gamification erfordert demnach ein Verständnis für die Zielgruppe, ihre Wahrnehmung und Einstellungen. Zukünftige Forschungen sollten sich darauf konzentrieren, altersspezifische Strategien zu entwickeln, um das Potenzial von Gamification effektiv im Rahmen von selbstgesteuerten non-formalen Bildungsangeboten wie Online-Lernplattformen nutzen zu können.
VITAMIN D, CALCIUM, AND PHOSPHORUS STATUS IN CHILDREN WITH SPINA BIFIDA
Authors: Boyarchuk Oksana , Hlushko Katerina , Dobrovolska Lesya , Hrekh Anastasiia , Savuliak Yaroslav , Vorontsova Tamara , Volianska Liubov
Published: July 2024

Introduction. Children with spina bifida (SB) are at the highest risk of developing vitamin and mineral deficiencies, including vitamin D, due to a sedentary lifestyle, prolonged indoor stays, and dietary peculiarities.
The aim of our study was to determine the dietary intakes of vitamin D, calcium, and phosphorus in children with spina bifida and the concentration of these nutrients in the serum of children with SB.
Materials and Methods. The study included 20 children aged 2 to 17 years with congenital neural tube defect (spina bifida). The control group consisted of 67 healthy children aged 6 to 17 years. To determine the dietary intakes of vitamin D, calcium and phosphorus, children or their parents were surveyed using a questionnaire containing questions about the amount of consumption of certain food products over the week. The total amount of vitamin D, calcium, and phosphorus in the weekly diet were calculated, as well as their average daily intakes with food and overall. The concentration of 25-OH vitamin D, calcium, and phosphorus in the blood serum was determined using an enzyme immunoassay.
Results. Among the examined children with SB, girls predominated (70.0%). Physical development delay and undernutrition were identified in 3 (15.0%), overweight - in 6 (30.0%) children. Most children with SB exhibited clinical manifestations of mineral metabolism disorders: body proportion disturbances (55.0%), posture disorders (40.0%), scoliosis and/or chest deformity (50.0%), caries (40.0%). Despite the presence of dairy, meat, and fish products in the weekly diet of all children with SB, their quantity was insufficient to meet the daily needs for vitamin D, calcium, and phosphorus. Inadequate intake of vitamin D from food occurred in 70.0% of children, calcium deficiency in 90.0%, phosphorus deficiency in 80.0%, with the alimentary provision of calcium and phosphorus in children with SB being significantly lower than in healthy children (p=0.0027 and p=0.0047, respectively).
Optimal levels of vitamin D in the blood serum were observed in only 10.0% of children with SB, which was twice less than in healthy children, while its deficiency was observed 1.5 times more often in children with SB than in healthy children. Half of the patients with SB had reduced calcium levels, and 70.0% had reduced phosphorus levels.
Conclusions. The study results demonstrate a wide prevalence of vitamin D deficiency and insufficiency (in 90.0%), calcium and phosphorus deficiency in children with SB, indicating the need for additional intake of these nutrients alongside dietary and lifestyle corrections. Further research on a larger cohort of patients with supplementation regimens is necessary to reduce the risk of complications and improve the quality of life for children with SB.