bluuebunny/crossref_metadata_2025 huggingface dataset:
Reseña libro "Innovación docente en Educación Superior. Interacción, participación y colaboración"
Authors: García García Javier
Published: December 2024

Reseña de la obra "Innovación docente en Educación Superior. Interacción, participación y colaboración".
Autores: Álvarez Álvarez, S. Pinedo González, R. (Eds.)ISBN: 978-84-18583-04-9Editorial: Agilice DigitalAño de edición: 2023Lugar de edición: EspañaNº Edición: 1ªPáginas: 403Idioma: Castellano
Integración de la Inteligencia Artificial en decisiones curriculares: Análisis del plan curricular de la asignatura: Empresarialidad (Código 4121) de la Escuela de Ciencias de la Administración de la UNED, Costa Rica
Authors: Vargas Manuel
Published: December 2024

El artículo examina la incorporación de la inteligencia artificial (IA) en el curso de Empresarialidad (Código 4121) de la ECA-UNED, con el objetivo de optimizar el proceso de enseñanza-aprendizaje y preparar a los estudiantes para un entorno laboral dinámico, sin descuidar una gestión curricular inclusiva. Esta integración enfrenta desafíos éticos vinculados a la equidad, privacidad y la toma de decisiones curriculares, desde la perspectiva del educador y de la administración educativa. Para abordar estos retos, la Cátedra de Administración de la ECA-UNED ha implementado estrategias como garantizar el acceso equitativo a la tecnología, proteger la privacidad de los datos estudiantiles y fomentar la interacción humana en el proceso educativo. El análisis concluye que la IA tiene un gran potencial para transformar la experiencia educativa al personalizar el aprendizaje y mejorar tanto la eficiencia como la efectividad del proceso educativo. Asimismo, se resalta su capacidad para aplicarse a diversos enfoques curriculares, como los técnicos, prácticos, de transición, crítico-sociales, tecnológicos y de autorrealización.
Protocol for the development of Polish clinical guidelines for the management of patients with systemic lupus erythematosus
Authors: Makowska Joanna , Kwiatkowska Brygida , Krajewska-Włodarczyk Magdalena , Batko Bogdan , Stajszczyk Marcin , Świerkot Jerzy , Żuber Zbigniew , Leszczyński Piotr , Sebastian Agata , Władysiuk Magdalena , Walecka Irena , Chmielewski Michał , Stasiołek Mariusz , Maślińska Maria
Published: December 2024

Introduction

Systemic lupus erythematosus (SLE) is a complex, chronic autoimmune disease that causes multi-organ inflammation and damage. Left untreated or inadequately managed, SLE can lead to severe organ dysfunction, disability, and reduced quality of life. In Poland, the absence of standardized, evidence-based clinical guidelines tailored to local resources and practices has created inconsistencies in SLE management. The purpose of these guidelines is to provide clear, evidence-based recommendations for the treatment and management of adult patients with SLE in the Polish healthcare system. These recommendations aim to align clinical practices with international standards, optimize treatment strategies, standardize patient care, and improve health outcomes while guiding healthcare policy.

Material and Methods

The adaptation process follows the ADAPTE Collaboration guidelines, the GRADE methodology, and the Evidence to Decision (ETD) framework. An interdisciplinary Working Group (WG), comprising experienced rheumatologists, organ-specific specialists, young rheumatologists, and a patient representative, will develop the guidelines. Key steps will include: 1) creation of clinical questions using the PICO format; 2) systematic search of relevant international guidelines (EULAR, ACR) and national sources; 3) evaluation of identified guidelines using the AGREE II instrument to ensure methodological quality; 4) formulation of recommendations through consensus-based discussions, addressing clinical treatment, monitoring, and care organization.

Scope and implementation

The guidelines cover pharmacological interventions for SLE, including hydroxychloroquine, glucocorticosteroids, immunosuppressive drugs biologics. Specific focus areas include treatment of organ-specific manifestations, management during pregnancy, treatment of disease flares, maintenance therapy, monitoring, and comorbidity management. The finalized document will undergo external review and be published in both Polish (on the Polish Society for Rheumatology website) and English (in the journal Reumatologia) as open access. Implementation strategies will include dissemination through scientific journals, presentations at conferences.

Conclusions

These guidelines aim to provide a standardized framework for SLE management in Poland. By implementing evidence-based recommendations, they will support healthcare providers in improving patient outcomes, optimizing resource allocation, and addressing the unique challenges of SLE within the Polish healthcare system.
Engelli istihdamında korumalı iş yeri: Avrupa Birliği ülkelerinden farklı uygulamalar
Authors: Korkmaz Burak Can
Published: December 2024

Engelli bireyler istihdama katılım noktasında birçok güçlük yaşamaktadır. İşgücü piyasasından dışlanan ve istihdama katılımda zorlanan engelli bireyler için iş hayatı doğrudan yaşam kalitelerini artırması yönüyle büyük bir öneme sahiptir. Dezavantajlı bir grup olmaları açısından sosyal politikaların hedefinde yer alan engelli bireylere yönelik istihdam politikaları dünya genelinde uygulanmakta fakat özellikle engel oranı yüksek olan bireyler için normal işgücü piyasasına katılımları öncesinde düşünülen korumalı iş yeri uygulamasına ilişkin görüş birliği bulunmamaktadır. Dolayısıyla başarılı uygulama örneklerinin incelenmesine ihtiyaç vardır. Bu noktada Avrupa Birliği ülkelerinde etkili sosyal politikaların uygulanması sayesinde engelli istihdamının yüksek olduğu tespit edilmiştir. Bu çalışma kapsamında, korumalı iş yeri uygulamasına yaygın bir şekilde başvuran Avrupa Birliği üye ülkelerindeki uygulama pratiklerinin açıklanması ve korumalı iş yeri uygulamasının bu ülkelerdeki mevcut durumunun tartışılması yoluyla politika önerileri sağlanması amaçlanmıştır. Korumalı iş yeri uygulamasının engel oranı yüksek olan bireylerin rehabilitasyonunun sağlandığı geçici bir istihdam modeli olması açısından faydalı olduğu söylenebilir. Bununla birlikte düzenli olarak takip edilmesi sağlanarak rehabilitasyon süreçleri tamamlanan bireylerin normal işgücü piyasasına geçişinin öncelik haline getirilmesi, korumalı iş yeri uygulamasını izole eden yerine geliştiren bir model olması yönüyle öne çıkarabilir.
Efektivitas Kebijakan Integrasi Zakat dan Pajak untuk Pembangunan Ekonomi Umat
Authors: Dasri Dasri
Published: December 2024

Kebijakan integrasi zakat dan pajak menjadi solusi inovatif dalam mendukung pembangunan ekonomi umat di Indonesia. Zakat sebagai kewajiban syariat dan pajak sebagai kewajiban negara memiliki potensi besar jika dikelola secara terintegrasi. Penelitian ini bertujuan untuk menganalisis efektivitas kebijakan integrasi zakat dan pajak, tantangan yang dihadapi, serta peluang implementasinya dalam konteks pembangunan ekonomi umat. Metode yang digunakan adalah pendekatan kualitatif deskriptif dengan pengumpulan data melalui wawancara mendalam dengan pemangku kebijakan, analisis dokumen, dan studi literatur. Hasil penelitian menunjukkan bahwa kebijakan integrasi zakat dan pajak dapat meningkatkan partisipasi masyarakat dalam membayar zakat, memperkuat peran lembaga zakat, dan mendorong distribusi kekayaan yang lebih merata. Namun, tantangan utama meliputi harmonisasi regulasi, transparansi lembaga zakat, dan kebutuhan edukasi masyarakat. Contoh sukses integrasi di Malaysia menunjukkan pentingnya dukungan regulasi yang kuat dan sistem informasi terintegrasi untuk memastikan implementasi yang efektif. Penelitian ini merekomendasikan penguatan regulasi, penggunaan teknologi informasi, dan peningkatan transparansi untuk mendukung keberhasilan kebijakan ini. Dengan pendekatan yang komprehensif, kebijakan integrasi zakat dan pajak berpotensi menjadi instrumen strategis dalam menciptakan sistem pembiayaan pembangunan yang berkeadilan dan berkelanjutan, serta memperkuat pemberdayaan ekonomi umat di Indonesia.
HUMANIZATION
Authors: Garbo Pinto Elda , Aguiar Sanches Cinthia , Aparecida Braga de Oliveira Elcie , Gomes da Silva Paula , Cristina dos Santos Darruiz Katia , De Oliveira Florentino Anelvira , Da Costa Natanael , Lopes Chilerne , Rosana Trevisani Corrêa Cláudia , Marques da Rocha Hoelz Cássia
Published: December 2024

Introduction: Humanization in nursing care has gained prominence as an essential strategy to improve the quality of healthcare services. The practice of humanization considers not only the technical aspects of care but also the emotional, social, and spiritual elements of the patient, promoting a more comprehensive and personcentered approach. Objectives: To analyze the contributions of humanization in emergency, urgent care, and intensive care services, highlighting its positive impacts on patients’ lives and nursing practice. Methodology: This is a type of bibliographic study, with a descriptive methodological approach, with searches in health databases. The sample consisted of eight articles selected and reviewed between August and October 2024.Results: The analysis of the research indicates that humanization, when systematically applied, produces significant outcomes, such as strengthening the bond between nurses and patients, improving the quality of care, and enhancing user satisfaction. However, challenges were also identified, including a lack of resources and training, which hinder the full implementation of this approach. Humanization involves not only adhering to policy guidelines but also adopting compassionate practices, effective communication, and holistic care, factors that make the hospital environment more welcoming and efficient. Final Considerations: Despite the obstacles encountered, humanization has the potential to transform the patient experience and improve the quality of work for nursing professionals. Continuous efforts are essential to strengthen this approach in various healthcare contexts.
A construção de um papel social e político para a publicidade e sua relação com o Estado Novo brasileiro
Authors: Carvalho Marina Helena Meira
Published: December 2024

Este artigo analisa a formulação de uma legitimidade para a publicidade e para os publicitários entre o final da década de 1930 e o início da de 1940. Questionamos como a construção de um papel social para a publicidade aponta para as relações construídas entre a área publicitária e o Estado Novo. Para isso, analisamos documentações, livros de memória, manuais profissionalizantes e artigos publicados em jornais e revistas especializadas para entender como eram realizadas as narrativas de aproximações e distanciamentos com o governo varguista. Elas aconteciam tanto de forma explícita quanto pela divulgação de representações consonantes ou dissonantes com os ideólogos estadonovistas.
A capa e a contracapa do “livro de imagens luminosas”: processos civilizatórios e descivilizatórios no cinema nacional durante o Estado Novo (1937-1945)
Authors: Yashinishi Bruno José , Honorato Tony
Published: December 2024

O presente artigo aborda a temática dos processos civilizatórios e descivilizatórios no cinema nacional brasileiro durante a ditadura do Estado Novo. Nesse contexto em que são relembrados os 70 anos do suicídio de Getúlio Vargas, esse texto objetiva investigar e demonstrar as dinâmicas conflituosas do processo social do cinema brasileiro durante a ditadura varguista, bem como as relações também conflituosas, entre mídia, sociedade e poder. Para tanto, fundamenta-se na sociologia e abordagem histórica de Norbert Elias, cujos constructos podem fornecer uma análise exploratória sobre a relação entre Estado, poder e cinema no Brasil governado por Vargas. O texto problematiza a relação entre política e cinema no Estado Novo; o papel conferido ao cinema no processo civilizatório; e, o processo descivilizatório resultante das paradoxais políticas estado-novistas voltadas ao setor cinematográfico.
A repercussão da carteira profissional entre os comerciários cariocas a partir do jornal A Noite (1932-1935)
Authors: Pegoraro Mônica Renata Schmidt , Da Silveira Marcos César Borges
Published: December 2024

O artigo, a partir da análise do vespertino carioca A Noite, aborda a atuação do Ministério do Trabalho, Indústria e Comércio (MTIC) na implementação da carteira profissional, criada pelo decreto nº 21.175, de março de 1932. Examina como segmentos organizados da classe trabalhadora, especificamente a União dos Trabalhadores do Comércio (UEC) do Rio de Janeiro, reagiram à imposição da carteira profissional por parte do governo Vargas. Apesar dos esforços do MTIC em demonstrar a importância e a confiabilidade da carteira laboral, a nova identificação profissional encontrou resistência entre os empregados do comércio. Essa contrariedade estava relacionada ao apego dos trabalhadores às antigas carteiras sindicais, mas também em virtude do temor de que os patrões poderiam lançar registros desairosos aos trabalhadores na carteira profissional, prejudicando-os, entre outras coisas, na obtenção de emprego.
De degenerados e aventureiros a fortes portadores da brasilidade: a reabilitação dos trabalhadores nordestinos durante o Governo Vargas (1930-1940)
Authors: Pereira Pedro Jardel Fonseca
Published: December 2024

Os trabalhadores migrantes nordestinos aparecem em alguns discursos da Revista do Conselho de Imigração e Colonização (CIC), imprensa do governo de Getúlio Vargas, como um sujeito avesso ao trabalho, perverso, aventureiro, degenerado biologicamente e doente. No entanto, também é possível identificar uma perspectiva de reabilitação e valorização desse sujeito, como o portador da brasilidade, forte, corajoso, ativo e conquistador. Neste sentido, o objetivo deste artigo é identificar as vertentes de pensamentos que cada uma dessas interpretações se alinhava e analisar o motivo que levou os nordestinos a serem valorizados nos discursos do governo. As informações obtidas na Revista do CIC foram analisadas com base na Análise do Discurso. Por um lado, os intelectuais colaboradores da Revista eram adeptos de teorias raciais e interpretavam os nordestinos como aventureiros e degenerados biologicamente. Por outro, atuavam os partidários do sanitarismo que defendiam que não era a raça que causava a morbidade e as doenças nos nordestinos, mas sim os fatores sociais, a falta de proteção, higiene e educação.
Unforeseen Finding of Deep Vein Thrombosis During Treatment of Disseminated Staphylococcus Aureus Infection – A Case Report
Authors: Ong Jia Cheng , Samsudin Ahmad Hadif Zaidin , Munajat Ismail , Ilias Mohamad Ikram
Published: December 2024

We reported a case of disseminated Staphylococcus aureus infection involving bone and pneumonia in a 2-year-10-month-old boy. He presented with fever, refused to walk and swollen right thigh and was diagnosed with right thigh intramuscular deep abscess. Serial X-ray, MRI femur and blood culture confirmed osteomyelitis with Staphylococcus aureus bacteremia. The disease was complicated with Staphylococcus aureus pneumonia, long segment thrombosis involving right common femoral vein till external iliac vein and fracture right neck of femur. He received 6 weeks of intravenous cloxacillin along with daily subcutaneous fondaparinux. Multiple wound debridement had been performed and the fracture was managed using hip spica. Disseminated Staphylococcus aureus infection involves at least two distant organs with presence of Staphylococcus aureus from at least one normally sterile body fluids. Combined surgical intervention and antibiotics therapy are necessary to cure the disease. Complication like deep vein thrombosis must be detected early to improve outcome.
Risk assessment of Atmospheric Column Overhead Product Drum
Authors: Dib Khawla , ZENNIR Youcef , Bounezour Hichem
Published: December 2024

The risk analysis plays an important role in the risk management process. Its objective is to identify significant adverse consequences, then assess their severity in order to decide on measures to control the risk. Our study involves conducting a risk analysis related to an un-stabilized naphtha separator ball from the Topping unit located at the Skikda refinery. We applied the HAZOP approach to identify accident scenarios that could be generated by this hazardous equipment. The modeling of the consequences of the chosen phenomenon, which is the BLEVE, was carried out using the PHAST software.
The Role of Instagram Social Media as a Marketing Communication Strategy in the Era of Digital Transformation of the Banking Industry
Authors: Ayu Agustriana Renny
Published: December 2024

Especially in the financial sector, social media plays an important role in managing marketing communications strategies in this era of digitalization. This study aims to analyze how the role of the use of Instagram social media on marketing communication strategies that can be applied by the banking industry. This study employs a comprehensive approach, utilizing literature analysis and the Systematic Literature Review (SLR) methodology. A total of 128 Scopus articles were meticulously identified through the Publish or Perish platform, supplemented by the utilization of Mendeley and Vosviewer applications. Subsequently, these articles were refined to 96 journal articles deemed pertinent for in-depth descriptive analysis. The results illuminate the potential for banks to capitalize on various social media functionalities, including photo uploads, fostering account popularity, and employing targeted advertising, as viable strategies to attain their marketing objectives. With the right approach, banks can increase consumer engagement, increasingly global market reach and Brand image is stronger through social media. The implications of this research include practical guidance for banking practitioners in designing successful marketing communication strategies in this digital age, as well as contributions to the development of knowledge in the field of marketing and social media. Thus, this research provides valuable insights for the banking industry and leads to more research that will help understand how social media plays a role in banking marketing.
Corporate Communications and Public Relations: Technological Transformation and Digitalization Towards Society 5.0
Authors: Constantin Natasha , Nelwin Raynaldi , Irwansyah
Published: December 2024

The insurance sector is undergoing a substantial shift in the swiftly changing environment of society 4.0, entering society 5.0 marked by digitization, mobile technologies, and artificial intelligence (AI). The formerly deemed conservative sector increasingly embraces innovative technology to improve operational efficiency and transform consumer interaction. This paper examines the influence of mobile and AI technologies on corporate communication and public relations, explicitly analyzing their effects on the insurance industry via the perspective of technological determinism. The objective is to examine how new technologies transform consumer interactions, trust dynamics, and organizational tactics while addressing ethical issues such as AI transparency and data protection. This study, rooted in technological determinism, highlights technology's independent and socially influenced effects on organizational behaviors. It uses a qualitative approach, phenomenological method, and semi-structured interviews with industry experts to investigate lived experiences and insights. The findings indicate that mobile platforms improve consumer interaction through immediacy and accessibility, while AI enhances operations through predictive analytics and automation. Nonetheless, issues about diversity and ethical responsibility persist as significant concerns. The research suggests that mobile and AI technologies serve as transformational agents, necessitating enterprises to reconcile technical innovation with ethical accountability. By implementing inclusive, transparent, and proactive communication strategies, insurance businesses may use these technologies to cultivate trust, enhance stakeholder relationships, and adeptly negotiate the intricacies of Society 4.0. This study offers a framework for incorporating developing technology into corporate communication and public relations by social norms and expectations.
Physicochemical characterization of siliceous sands of Seme-Podji/Benin: An application for the synthesis of silica particles
Authors: Glitho Houefa Annick Leslie , Osseni Semiyou Ayele , Bonou Sidoine Sourou , Plaisier Jasper , Gigli Lara , Sagbo Etienne , Chouti Waris Kewouyemi
Published: December 2024

In order to valorize locally available natural resources, the silica sand in the commune of Sèmè-Podji in Republic of Benin was characterized. The results obtained by particle size, chemical analysis, X-ray diffraction (XRD), and FT-IR analysis confirmed that these sands contain a high percentage of silicon dioxide, with a value approximately equal to 90 wt.%. Low Fe2O3 and Al2O3 content (<1 wt.%) and minor oxides such as K2O, Na2O, TiO2, and P2O5 (<0.6%) were also present. The size distributions of the particles show that the largest portion of the sand is found between 63 and 125 μm. This portion represents the one that contains the most silica. From this sand, silica particles were synthesized by the sol-gel method. The results obtained by X-ray diffraction (XRD), FT-IR analysis, and scanning electron microscopy (SEM) reveal the formation of pure amorphous silica.
Synthesis and crystal structure determination of a new 1D polymer adduct of 1,2-di(pyridin-4-yl)ethane, based on B-N dative bonded eight-membered cyclo-1,3,3,5,7,7-hexaphenyl-1,5-dibora-3,7-disiloxane
Authors: Bull Okpara Sergeant , Don-Lawson Chioma
Published: December 2024

A novel 1D polymer of 1,2-di(pyridin-4-yl)ethane (L1), connected via B-N dative-bonded adduct with an eight-membered cyclo-1,3,3,5,7,7-hexaphenyl-1,5-dibora-3,7-disiloxane [Ph6B2Si2O4]·L1 was synthesized and characterized. The new compound [Ph6B2Si2O4]·L1 was prepared by the reaction of cyclo-1,3,3,5,7,7-hexaphenyl-1,5-dibora-3,7-disiloxane and bis(pyridyl)ethane in a mixture of diethyl ether and petroleum ether solvents at reflux. The 1D polymer [Ph6B2Si2O4]·L1 was characterized by single-crystal X-ray diffraction, nuclear magnetic resonance, and FT-IR spectroscopy. The single crystal X-ray diffraction studies reveal that the aforementioned compound crystalized in the monoclinic crystal system with a centrosymmetric space group of P21/n (no. 14), a = 16.5378(4) Å, b = 12.6201(3) Å, c = 20.4904(5) Å, β = 96.689(2)°, V = 4247.43(18) Å3, Z = 4, T = 173.0 K, μ(MoKα) = 0.130 mm-1, Dcalc = 1.233 g/cm3, 14630 reflections measured (4.96° ≤ 2Θ ≤ 56.424°), 8424 unique (Rint = 0.0235, Rsigma = 0.0460) which were used in all calculations, the final R1 was 0.0455 (I > 2σ(I)) and wR2 was 0.1201 (all data). Furthermore, the compound exhibits various noncovalent interactions in the crystal packing, such as intermolecular and intramolecular, as well as hydrogen bonding. This study demonstrates the potential for making novel materials via the combination of cyclodiboradisiloxanes (Lewis acid) and nitrogen-containing ligands (Lewis bases).
Environmentally benign synthesis of substituted iodinated flavones as precursors for prenyl-/geranyl flavones from the corresponding chalcones
Authors: Khan Sumaiya , Liza Umme Aiman , Banik Dipan , Aman Md Aman Ullah , Happy Kamrunnahar , Arjaya Amit Chandra , Hossain Mohammad Mamun
Published: December 2024

Flavones have biological properties because of the existence of oxoheterocyclic ring moieties, and day by day create research interest areas because of their important biological activity. Iodine-substituted flavones were synthesized from the corresponding chalcones through an exhaustive iodination reaction. Generally, it is seen that halogenated flavones show better biological activity. Moreover, the introduction of iodine in the ring moiety facilitates the incorporation of highly active side chains, such as prenyl and geranyl groups through the formation of C-C bonds by numerous coupling reactions such as Sonogashira coupling. To achieve such target molecules, a planned chemical synthesis was conducted. For comparison, microwave irradiation (MWI) and conventional heating (CH) methods were used to synthesize a series of iodine-substituted flavone compounds with different substitutes (4a-d) from their corresponding chalcones (3a-d). Unfortunately, 3e chalcone (1-hydroxynapthalene substituted flavone) did not convert to 4e flavones. In the microwave method, a notable decrease in time required in the reaction and an increase in % yield of the reaction were remarked. Characterization and conformation of all synthesized compounds were done using ultraviolet, infrared, and nuclear magnetic resonance spectroscopy and elemental analysis.
Tetrachloro-(acetylacetonato)stannate(IV) and tri-iodocadmate(II) stabilized by a heptacyclic cation: Synthesis, characterization, and crystal structure
Authors: Ndiolene Adrienne , Diop Tidiane , Boye Mouhamadou Sembene , Diasse-Sarr Aminata
Published: December 2024

The tin (IV) and cadmium (II) complexes were synthesized in mixture, the ligand 4,4'-(ethane-1,2-diylbis(azanylylidene))bis(pent-2-en-2-ol), and the halide metal (SnCl2 or CdI2). Complex synthesis involves partial hydrolysis of the ligand followed by condensation cyclization. The new tin complex obtained crystallizes in the monoclinic space group P21/n with a = 8.5468(5) Å, b = 17.9907(9) Å, c = 12.7227(7) Å, β = 94.220(5) °, V = 1950.98(18) Å3 and Z = 4. The asymmetric unit consists of an anion tetrachloro-(acetylacetonato)stannate(IV) and a heptacyclic cation. The geometry of the complex is octahedral with cis coordination of the two oxygens of the acetylacetone. The cadmium complex crystallizes in the orthorhombic space group Pbca with a = 14.7395(9) Å, b = 8.5914(5) Å, c = 23.2825(13) Å, V = 2948.3(3) Å3, Z = 8. The geometry around cadmium is a deformed tetrahedron. The heptacyclic cation and the anionic complex are interconnected through hydrogen bonding interactions, specifically N–H···Cl or N–H···I, forming a network.
Methods for synthesizing hydroxamic acids and their metal complexes
Authors: Sow Ibrahima Sory
Published: December 2024

In previously published works, the antibacterial, antifungal, antimycobacterial and anticancer activities of hydroxamic acids (HA) and their complexes were reported. Our recently published work shows that aliphatic HA with a number of carbon atoms equal to 12 (C12) and its Fe(II), Fe(III), Ni(II), Cu(II) and Zn(II) complexes are significantly active against bacteria (Staphylococcus aureus, Escherichia coli), fungal (Candida albicans) and mycobacteria (Mycobacterium smegmatis). Furthermore, the inhibitory activities against biofilms of Mycobacterium tuberculosis, Mycobacterium bovis BCG, Mycobacterium marinum and Pseudomonas aeruginosa were observed with a large number of HA and their complexes. Suberoylanilide HA and resminostat were approved to treat cutaneous T cell lymphoma and in clinical trials to treat advanced hepatocellular carcinoma, respectively. In view of the interesting biological properties of this family of chemical compounds, the synthesis of HA has been reported in numerous research articles in recent years but this is the second review article dedicated to their synthetic methods and the first review for their complexes. The aim of this review is to highlight optimal and rational methods for the synthesis of HA and their complexes. HA are obtained in near-quantitative yields from carboxylic acid, ethyl chloroformate, N-methylmorpholine and hydroxylamine. As for their complexes, the synthesis methods described are fairly similar and would all appear to be optimal. The main criteria are the number of equivalents of HA, the type of metal salt or solvent used and the reaction conditions.
Cutting-edge bioorthogonal chemistry: Innovations, practical applications, and emerging trends
Authors: Chetry Anup Basnet
Published: December 2024

Bioorthogonal chemistry has emerged as a pivotal field in molecular science, offering transformative tools for applications in drug discovery, imaging, and molecular biology. This review provides a comprehensive analysis of recent advancements in bioorthogonal chemistry, emphasizing key innovations, practical applications, and future research directions. We explore state-of-the-art bioorthogonal reactions, including Staudinger ligation, strain-promoted azide-alkyne cycloaddition (SPAAC), and tetrazine ligation, detailing their mechanisms, advantages, and limitations. The review highlights significant innovations such as novel fluorogenic probes, improved catalysts, and enhanced reaction conditions that have expanded the utility and efficiency of these reactions. Practical applications are examined, showing how these advances have revolutionized fields like live-cell imaging, targeted drug delivery, and molecular labeling. Looking to the future, we discuss emerging trends and potential research avenues, including the integration of bioorthogonal chemistry with other advanced technologies and the development of new reaction methodologies. This review provides a detailed overview of the current state of bioorthogonal chemistry and outlines its future potential, serving as a valuable resource for researchers and practitioners in the field.
Integrating Tradition and Modernity in Islamic Higher Education
Authors: Slamet Riyadi  , Muhammad Ridha  , Mowafg Abrahem Masuwd  , Naser Ali Abdulghani  , Suhendri
Published: December 2024

This study examines the integration of pesantren traditions with modern higher education at STAI As-Sunnah, an Islamic college in Indonesia. Employing a phenomenological approach, the research analyzes how this institution balances traditional values with contemporary educational demands. Key findings highlight STAI As-Sunnah's success in maintaining a focus on Arabic language learning and Islamic values while offering accredited study programs. However, the study also identifies discourses surrounding gender inclusivity, access to technology, and the balance between tradition and modernity. The study concludes that adopting more inclusive and adaptive approaches, such as blended learning, may help STAI As-Sunnah become an innovative model in Islamic higher education, contributing significantly to the development of Islamic education in Indonesia.
Investigation of the Relationship between Personality Traits and Positive and Negative Affect
Authors: Öğretir Özçelik Ayşe Dilek , Özkanat Zeliha
Published: December 2024

This study aims to investigate the relationship between personality traits and positive and negative affect of university students. The study was conducted on a sample of 500 university students (246 male and 256 female) attending […] University in Turkey who voluntarily participated in the research. The participants were selected through snowball and convenience sampling methods. Giessen Test Self-Form, The Positive and Negative Affect Schedule (PANAS), and demographic information forms were used to conduct the research. Independent t-test, ANOVA, Pearson correlation coefficient, and regression analyses were employed to examine the relationships between variables. The results revealed a weak statistically significant relationship between personality traits and positive and negative affect of university students. The findings are discussed in the light of personality traits and positive and negative affect literature.
Day Care Centers for Alzheimer’s Patients in Türkiye: Demographic Change and Care Ethics, Political and Economic Implications
Authors: Asadi Faezi Sanam , Ozgur Ozlem , Cetinkaya Bilge , Vural Melih , Ayan Fatma Sila
Published: December 2024

Advancements in healthcare have extended life expectancy, accelerating the global shift towards aging populations and creating a growing need for comprehensive geriatric care. Among the most pressing challenges is dementia, with Alzheimer's disease (AD) standing as a significant societal and policy concern. AD is a progressive neurodegenerative disorder characterized by the irreversible decline of cognitive functions, including memory, reasoning, and problem-solving, leading to a loss of independence. Its onset, influenced by genetic, environmental, and lifestyle factors, poses profound socio-economic and emotional challenges for patients and caregivers alike. Current healthcare and social support systems often fall short in addressing the complex needs of individuals with Alzheimer’s and their families, highlighting critical gaps in policy and service provision. Family caregivers bear the dual burden of emotional distress and financial strain, with limited access to adequate support. Expanding specialized services, such as daycare centers, staffed by multidisciplinary professionals, including gerontologists, psychologists, physiotherapists, and social workers, provides a sustainable solution. These centers not only enhance the quality of life for patients but also alleviate the socio-economic pressures on families and the state. Addressing Alzheimer’s care within the broader context of demographic transformation requires an integrated approach, combining public awareness, early diagnosis initiatives, and robust policy reform. Investments in community-based care infrastructure and caregiver support are vital to fostering fair and inclusive outcomes in aging societies. This transformation must be prioritized to mitigate the marginalization of older adults and ensure societal resilience in the face of aging population trends.
عقدُ الهُدنةِ في التّشريعِ الإسلاميِّ والقانونِ الدّوليِّ
Authors:   وزارة التربية المديريّة العامّة لتربية بغداد الكرخ, ياسين عكلو غسّان
Published: December 2024

الحمد لله المتفضل على الإنسان بنعمته، والصلاة والسلام على نبيه ورسوله وآله الخيرة المنتجبين وصحبه والتابعين ومن تبعهم بإحسانٍ إلى يوم الدين. تهدف الدراسة الى البحث في موضوع عقد الهدنة، بتعريفه وشروطه وحالات الالتزام به، ومقارنة ذلك كله بأصوله الكلية في القانون الدولي. ما نشهده في هذه الأيام من انتفاضة عظمى للفلسطينيين (طوفان الأقصى)، توجب على الناس أجمعين لهم النصرة بالقول والعمل ما استطاعوا إلى ذلك سبيلاً، ولو بالدعاء بإتمام هدنة تتوافق شروطها مع ما فرضه التشريع الإسلامي من شروط لصحتها، تمكنهم من حشد قوتهم وإعادة تنظيم صفوفهم، وتوفر الحد الأدنى من احتياجات شعبهم، أيدهم الله بنصره وتغمدت رحمته شهداءهم، وشافى جرحاهم وفك أسر أبنائهم وحرر أرضهم ومقدساتهم من دنس المعتدين، إنه هو القوي العزيز
الشَّيخ أحمد فائز البرزنجي (ت: 1338هـ- 1918م)وجهودُه في علمِ الكلامِ كتابُه خُلاصة العقيدة شرح الدُّرَّة الفريدة أُنموذجًا (دراسةٌ وصفيّةٌ تحليليّةٌ)
Authors:   جامعة كويه قسم التربية الدينية, ابوبكر على حكيم , فقى علي جواد ,   جامعة كويه قسم التربية الدينية.
Published: December 2024

تتمحور هذه الدراسة حول عرض الاعتقادات الإسلامية التي قدّمها أحد من علماء الشعب الكوردي؛ وهو (احمد فائز البرزنجي) رحمه الله تعالى كونه عالمًا متكلمًا بارعًا، اذ عاش في نهاية النصف الأول، وبداية النصف الثاني من القرن التاسع عشر، والسنوات الأخيرة لإمارة البابانيين والموافق لعهد الخلافة العثمانية. وقد تم اتباع المنهج الوصفي التحليلي في هذه الدراسة، اذ استعمل فيها الدليل النقلي والعقلي، ثم تركزنا على بيان منهجه في كتابه "خلاصة العقيدة في شرح الدرة الفريدة"، فناقشنا أقوال المتكلمين في المدارس الإسلامية المشتهرة
صورةُ الأُمِّ مرثيّةً في الشِّعرِ العراقيِّ الحديثِ ضياء عبد الكاظم جبر
Authors:   كليّة التّمريض / جامعة بغداد, عبد الكاظم جبر ضياء
Published: December 2024

الرثاءُ فنٌ من الفنون الشعرية الجميلة في الآداب الانسانية، وفي أدبنا العربي الخالد، على امتداد عصورهِ، وهو موضوع ٌرئيسٌ من موضوعات الشعر العربي في عصر ما قبل الاسلام، فقد رثى الشاعر الأحبّة، والخلّان، ووقف عند قبورهم، نادباً، باكياً، متذكراً الأيام الجميلة، والصحبة والاعزّة، فقد امتزجت في هذا الفن روعة الخيال مع الحقيقة المؤلمة، فضلاً عن عمق العاطفة، وحرارة المشاعر، وجمال الصورة الرثائية الصادقة، التي يرسمها الشاعر دونما تأثير خارجي مصطنع فيه، سوى الوفاء للأحبّة الذي عبّر عن صدق داخلي، أو للروابط الإنسانية التي تجمع بينه وبين مرثيه.
فالرثاءُ، غرضٌ قديمٌ، من أغراض الشعر العربي، ولا نبالغ إذا قلنا: إنّ الإنسان عرف هذا اللون من الشعر منذ أنْ عرف الموت، فقد اقترن الرثاء بالموت، منذ فجر التاريخ، وأخذت الأمم في البادية والحضر برثاء موتاها، والوقوف على قبورهم وتخليد ذكراهم والتحسر واللوعة على رجالاتهم. وكان ذلك شائعاً في أدب وادي الرافدين، وكذلك في الأدب المصري القديم، الذي قدم لنا بعض القصص الاسطورية، التي انتشرت عند الفراعنة في أسطورة (إزيسس وازريريس وأخيه ست)، فيصور لنا رثاء (أزيسا) في بكائها لزوجها (أوزيريس)، الذي قتله أخوه (ست) طمعاً في زوجته، وتمتد هذه الصورة الرثائية من جيل إلى جيل عند المصريين
DENTAL EDUCATION DIGITIZATION: VIRTUAL REALITY (VR) AND AUGMENTED REALITY (AR)
Authors: Onder Merve , Orhan Kaan
Published: December 2024

In dental education, the role of practical training is crucial. Dental students undergo numerous practical training sessions during the first three years to enhance their manual and visual skills. Technological advancements have found their place in the field of dentistry, as in every other area. Three-dimensional (3D) imaging and printing, computer-aided design and computer-aided manufacturing (CAD/CAM), artificial intelligence (AI), virtual reality (VR), and augmented reality (AR) based applications are building a significant presence in both dental education and practice.
Objective and Method: Our aim in this review is to investigate the impact and significance of VR and AR in dental education. Therefore, a comprehensive literature review was conducted on the subject, and the results were evaluated and summarized
Results and Conclusions: One of the most significant advantages of AR and VR systems is their ability to facilitate manual skill acquisition and minimize errors with instant feedback. The major distinguishing feature of AR systems from VR systems in education is the absence of disconnection from reality in the former case. AR gives students the feeling of being in a real environment and guides them during dental treatment. Although AR and VR applications seem easily integrable into dental education, further research is needed for these emerging digital technologies.
The Role of Self-Regulation and Motivation in Secondary School Students’ English Self-Efficacy
Authors: Akdoğan Nuray , Toprak Emre
Published: December 2024

The purpose of this research is to examine the role of self-regulation and motivation in the English self-efficacy of secondary school students and to investigate their relationship with various independent variables. This research aims to identify the factors influencing English proficiency in Türkiye and contribute to the consideration of these factors in the regulations made to improve language education in order to enhance the level of English language education. The research is conducted according to the correlational survey method. The sample of the research consists of 580 secondary school students studying in state schools affiliated with the Ministry of National Education in Kayseri province in the 2022-2023 academic year. In the research, “English Language Skills Self-Efficacy Scale”, “Perceived Self-Regulation Scale”, “Foreign Language Learning Motivation Scale” and “Personal Information Form” were used as data collection tools. In addition to descriptive statistics, t-test, Analysis of Variance, Tukey HSD multiple comparison test, and Stepwise Multiple Regression Analysis were used for data analysis. As a result of the research, it was found that secondary school students’ self-regulation skills, foreign language learning motivation, students’ gender, grade level, parental education level, family income level, the place where most of their life is spent, and English report card grade were significant variables in explaining their English self-efficacy.
The Effect of Augmented Reality Applications on Secondary School Students’ Achievement of Atom Models and Theirs Attitudes
Authors: Güngördü  Çevik Dilan , Yılmaz Zeynel Abidin
Published: December 2024

The aim of this study is to examine the effects of Augmented Reality (AR) applications, which are a new approach in education, on students' achievement and attitudes. For this purpose, on the basis of science education, a content, which was consistent with the syllabus, about atomic structure and atom models in the topic of structure and properties of matter was developed by the experts for the 7th grade students in secondary education and AR applications were integrated into the content. The Vuforia SDK software was used to design the content. The study was conducted on 205 secondary school students from six classes enrolled in a school in province of Gaziantep, in 2017-2018 academic year. Experimental group (n=103) and control group (n = 102) were randomly assigned. In this study, pretest-posttest with control group quasi-experimental design was used. The data of the study were collected using the achievement test, the Augmented Reality Applications Attitude Scale (ARAAS) and a semi-structured interview. The quantitative data were analyzed using t test while the qualitative data were analyzed using descriptive analysis. The results of the statistical analysis indicated that the teaching method integrated with AR applications was a more successful method in promoting students' achievement of Atomic Structure and Atom Models compared to the traditional teaching method. In addition, students with a high level of interest in technology have been more successful in the tests than those with less interested. On the other hand, the data from the ARAAS applied to the experimental group indicated that student attitudes are positive, they are satisfied with using the AR, they do not carry concerns about use and they want to use them in different courses in the future. The experimental group students, through the semi-structured interview form, reported that the AR applications made significant contributions to the educational environment and the teaching process.
Customary Practice of Tandok Sepapan in Mediating Tenurial Conflicts within the Community of Southeast Aceh Regency
Authors: Desky Sunawardi , Sofyan Hizir , Abdullah Irwan , Yusuf Rusli
Published: December 2024

This research aims to understand the relevance and practices of the Tandok Sepapan customary tradition in resolving Tenurial conflicts among the communities of Southeast Aceh Regency. This research is designed qualitatively using a case study approach.  The research was conducted in Peseluk Pesimbe Village, Deleng Pokhisen Subdistrict, and Bakti Village, Babul Makmur Subdistrict, for the Conservation Forest, and Tanjung Leuser Village and Gulo Village, Darul Hasanah Subdistrict, for the Conservation Forest in Aceh Tenggara District. The research findings demonstrate that the customary practice of Tandok Sepapan plays a crucial role in mediating tenurial conflicts within the community. Tandok Sepapan, as a traditional conflict resolution mechanism, has proven effective in resolving disputes related to land ownership and rights. This practice involves guided dialogue based on cultural norms and values, resulting in peaceful resolutions. The customary practice of Tandok Sepapan not only serves as a means to resolve conflicts but also strengthens social bonds, fosters trust, and maintains harmony and sustainability within the Southeast Aceh Regency community. A mediation approach considering customary norms and local wisdom creates space for dialogue, understanding, and reconciliation among conflicting parties, offering more sustainable and harmonious solutions in the local community context. The structured mediation process, from the appointment of the Head of Adat to the drafting of peace agreements, enables the search for culturally aligned solutions. Agreements made in customary meetings are based on fairness for both parties and are later formalized into peace agreements recognized as customary law by all involved.
Transformation of Educational Institution Management at Ilyas Karanganyar Islamic Boarding School
Authors: Purbiyanto Eko , Pamungkas Tri
Published: December 2024

Organizational transformation program is a strategic step that is not only an option, but also a necessity to ensure the sustainability and competitiveness of a company or organization. This transformation is closely related to the overall strategy, and often includes total changes involving all aspects of the organization, resulting in a completely new entity that is more adaptive to environmental changes. This transformation is very important so that the vision and mission of the organization can be realized optimally. This study aims to analyze the transformation process carried out by the Ilyas Karanganyar Islamic Boarding School, which includes the steps of planning, organizing, mobilizing, and supervising. The data sources in this study came from direct observation, interviews with related parties, and internal document analysis. The research method used is a qualitative approach with case studies to identify key findings related to productive, efficient, and effective collaboration in achieving common goals. The research findings show that innovation and change in education are key factors in increasing organizational competitiveness amidst the dynamics of ever-growing change.
Prognostication of differentiated thyroid cancer recurrence: An explainable machine learning approach
Authors: Idroes Ghazi M. , Noviandy Teuku R. , Idroes Ghalieb M. , Hardi Irsan , Duta Teuku F. , Hamoud Lama MA. , Al-Gunaid Hala T.
Published: December 2024

Differentiated thyroid cancer (DTC) generally has a favorable prognosis, but recurrence remains a concern for a subset of patients, highlighting the need for accurate predictive tools. While traditional methods, such as the American Thyroid Association (ATA) guidelines, are widely used, they may not fully capture the complex patterns in clinical data. To address this, we developed a machine learning model using LightGBM and enhanced its interpretability with SHAP (SHapley Additive exPlanations). Our model, trained on data from 383 DTC patients, identified response to initial therapy as the most significant predictor of recurrence, alongside age and risk level. The model achieved an accuracy of 93.51%, with precision and sensitivity of 94.23% and 96.08%, respectively, using only five key features selected through Recursive Feature Elimination (RFE). SHAP analysis provided clear insights into how these features influenced predictions, offering a transparent and interpretable approach to risk stratification. These results highlight the potential of explainable machine learning to improve recurrence prediction, support personalized care, and build clinician trust, while laying the groundwork for further validation in diverse populations.
Brain ability and its correlation in separation classes for men and women in Islamic educational institutions
Authors: Abdillah Nurul Lubab , Wantini Wantini
Published: December 2024

The purpose of this research is to find a step solution for how to manage classes based on gender while still optimizing the character of the brain. This research method uses a qualitative approach. The results of this research are the differentiation of male and female brains in general in the corpus callosum and Broca-Wernicke's area. This causes women to be more able to carry out several tasks at one time and women are better able to control their emotions. In addition, women also have better language skills, as reflected in the large number of vocabulary products. In Islamic educational institutions, the segregation of classes based on gender is a rule based on religion. In Islam men and women. And it was found that class separation based on gender had the following positive impacts: first, students were more focused. Second, growing awareness that there are boundaries with the opposite sex. Third, increasing learning outcomes.The results of this study have implications for educators to take attitudes and steps in class management by paying attention to existing characters and potential.