bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of the Effects of Marital Adjustment on Sexual Life Quality of Married Women
Authors: Tuncer SevinÃ§ KÃ¶se , Aydin Emin , KasimoÄŸlu Necla , AÄŸdemir Burcu , BaÅŸkan Sebahat AtalikoÄŸlu
Published: December 2018

Objective: The aim of this study is to determine the effect of marital adjustment on the quality of sex life in married women.Method: As a descriptive study, the universe of the present study consists of married women consulting to an education and research hospital and primary care clinics in a province while the sample is composed of 365 voluntary married women that are open to dialogue. In collecting the data, â€œInformation formâ€ containing socio-demographic background, â€œMarriage Adjustment form (MAF) and sexual life quality scale for womanÂ  (SFQSW) were used. In analysing the data, arithmetic mean, percentage, frequency, Mann Whitney-U test, Kruskall Wallis Analysis and Spearman Correlation Analysis were employed.Findings: Arithmetic score of the MAF is 43.58Â±9.83 and that of SFQSW is 79.88Â±19.57 while significant relation between the scores was found in positive direction (p<0.05).Results: The more marital adjustment increases in women, the better the sexual life quality is. In order to increase the level of well-being and life quality in marriage, nurses are suggested to counsel the couples and family consultants are advised to inform the families on sexual issues and improve their communication skills.
The Problems of Human Dignity and Human Rights in the Context of Bioethics
Authors: PIRUMYAN Tatevik , DAVTYAN Susanna
Published: December 2018

The article presents an analysis of the principles of human dignity and human rights from the viewpoint of bioethics, describes the development and modifications of the concepts of “human dignity” and “human rights” in different historical stages. The main purpose of the article’s detailed observation is a complete and true perception of the problems of human dignity and human rights in the contemporary globalized world. To implement the above-mentioned aim, the paper deals with different international conventions and declarations: Convention for the Protection of Human and Dignity of the human Being with regard to the Application of Biology and Medicine: Convention of Human Rights and Biomedicine, European Convention on Human Rights, Human Rights and Biomedicine: The Oviedo Convention and its Protocols, The Nuremberg Code, The UNESCO Universal Declaration on Bioethics and Human Rights, Universal Declaration of Human Rights, WMA Declaration of Geneva, WMA Declaration of Helsinki and WMA Declaration of Lisbon on the rights of the patient.
PERAN ALAM YANG DIKALAHKAN SANG SAPURBA DITINJAU DARI PERSPEKTIF ETIKA LINGKUNGAN
Authors: Lestari Puji , Waluyo Herman J. , Saddhono Kundharu
Published: December 2018

This study aims to reveal the concept of the role of nature from the view of Malays based on the type in Dikalahkan Sang Sapurba romance by Ediruslan Pe Amanriza. The method used is analytical descriptive with reference to environmental ethics and Kluckhohn. Data, in the form of sentences or paragraph quotes from romances, are classified and analyzed to obtain a complete understanding of environmental issues based on the concept of the role of nature. The results of the analysis show that the role of nature, which is believed to be both magical and real, will determine the form of identity of its social control. Magical roles provide sacred nature as a form of ecocentricism, while the real role symbolizesthat nature can be mastered or opposed which reflects the form of anthropocentrism from the perspective of environmental ethics. This study also shows that the real role is more dominant than the occult role so the end of the story is shown by the form of sad ending.
MELINTASI HORISON INTERPRETASI IDEOLOGIS DALAM NOVEL RITOURNELLE DE LA FAIM KARYA J.M.G.LE CLÉZIO
Authors: Pratiwi Dian , Udasmoro Wening
Published: December 2018

This research focuses on the study of  ideology in Ritournelle de la Faim by J.M.G. Le Clézio. Presenting main characters who are coming from the dominant class, the texts reveals its ambivalence forms. It stimulates  question towards the text resistence potential itself over the dominant ideology, whether the text itself is subversive or ultimately collapse under the dominant ideology. To analyze this issue, Frederic Jameson’s Political Unconscious theory is applied. The findings of this study are: 1) political horizon shows the text as the imaginary resolution over the social contradiction,  through critical works towards bourgeois class; 2) social horizon shows that the ideologeme can be found in the form of the society demoralization which creates the ambivalence of the characters. This ultimately deflects bourgeois values as a fantasy of an ideal life; and 3) modes of production has put the author as a cynical subject, where the author's ideology contained in the text has been distorted in a certain way by late capitalism ideology
EFFECT OF POLYMORPHISM OF APOE AND SLCO1B1 GENES ON THE COURSE OF MYOCARDIAL INFARCTION ASSOCIATED WITH ACUTE KIDNEY INJURY IN HOSPITAL AND LONG-TERM PERIODS
Authors: Siverina A. V. , Skorodumova E. A. , Kostenko V. A. , Pivovarova L. P. , Malyshev M. E. , Ariskina O. B. , Fedorov A. N. , Skorodumova E. G. , Rysev A. V.
Published: December 2018

THE AIM:to assess the effect of APOE and SLCO1B1 gene polymorphism on the course of myocardial infarction (MI) associated with acute kidney injury (AKI) in hospital and long-term periods.

PATIENTS AND METHODS:132 patients with МI were examined, which were divided into 2 groups: the first (I) – 68 patients with MI and AKI, the second (II) – 64 people with MI without AKI.

RESULTS:In the distribution of genotypes, polymorphism of Leu28Pro of the APOE gene in the studied groups was revealed that LeuPro was more often inherited in patients of group I – 20,6 %, the average value of total cholesterol (TC) – 6,01±0,3 mmol/l, and low density lipoproteins (LDL) – 3,37±0,21 mmol/l, compared with patients of group II, where the LeuPro genotype – 6, 2 %, TC – 5,03±0,3 mmol/l, LDL – 2,38±0,3 mmol/l, p<0,05. A similar situation was typical for the polymor phism Val174Ala SLCO1B1 gene, where ValAla in patients of group I-26,5 %, in II-12,5 %, p<0.05. In heterozygotes I sample TC-5,59±0,3 mmol/l, and LDL – 3,30±0,14 mmol/l, in group II TC – 5,19±0,29 mmol/l, LDL – 2,75±0,23 mmol / l, p<0,05. The clinical picture of the hospital period in patients with MI and AKI, proceeded with the development of a greater number of complications, which reflected in the high mortality in group I – 16,2 %, in group II – 4,7 %, p<0,05. In the posthospital period, against the background of atorvastatin administration in both study groups, there was a positive trend of decrease in TC and LDL, but it was not possible to achieve the targets. Mortality in the long-term period in group I – 15,4 %, in group II-2,0 %, p<0.05.

CONCLUSIONS:in patients with MI and AKI on the background of a more severe clinical course of the disease, both in hospital and in the long-term period, rare allelic variants of the genes APOE and SLCO1B1 were more often determined, which negatively affected the lipid profile.
KIDNEY DISEASE IN THE SETTING OF HIV INFECTION: CONCLUSIONS FROM A KIDNEY DISEASE: IMPROVING GLOBAL OUTCOMES (KDIGO) CONTROVERSIES CONFERENCE
Authors: Swanepoel C. R. , Atta M. G. , D’Agati V. D. , Estrella M. M. , Fogo A. B. , Naicker S. , Post Fr. A. , Wearne N. , Winkler Ch. A. , Cheung M. , Wheeler D. C. , Winkelmayer W. C. , Wyatt Ch. M. , Participants For Conference
Published: December 2018

HIV-positive individuals are at increased risk for kidney disease, including HIV-associated nephropathy, noncollapsing focal segmental glomerulosclerosis, immune-complex kidney disease, and comorbid kidney disease, as well as kidney injury resulting from prolonged exposure to antiretroviral therapy or from opportunistic infections. Clinical guidelines for kidney disease prevention and treatment in HIV-positive individuals are largely extrapolated from studies in the general population, and do not fully incorporate existing knowledge o f the unique HIV-related pathways and genetic factors that contribute to the risk of kidney disease in this population. We convened an international panel of experts in nephrology, renal pathology, and infectious diseases to define the pathology of kidney disease in the setting of HIV infection; describe the role of genetics in the natural history, diagnosis, and treatment of kidney disease in HIV-positive individuals; characterize the renal risk-benefit of antiretroviral therapy for HIV treatment and prevention; and define best practices for the prevention and management of kidney disease in HIV-positive individuals.
EVALUATION OF RELATIONSHIP BETWEEN MAXILLARY SINUS PATHOLOGIES AND OSTIUM DIMENSION: A RETROSPECTIVE CONE BEAM COMPUTED TOMOGRAPHY STUDY
Authors: BAYRAK Seval , USTAOĞLU Gülbahar , KURŞUN ÇAKMAK Emine Şebnem , ATAKAN Cemal
Published: December 2018

Objective: Maxillary
sinus ostium is the top section of the medial wall the and is hence poorly
placed from the point of view of free drainage; it opens into the narrow
ethmoidal infundibulum, inflammation of which can further break drainage, so
this may cause in the development of chronic maxillary sinusitis. This study
aims to evaluate maxillary sinus pathologies (MSP) and their possible relation
with maxillary sinus ostium dimensions.Material and Methods: Cone Beam
Computed Tomography (CBCT) scans which belong to 139 patients (52 male and 87
female) were retrospectively evaluated with regard to ostium dimensions and the
presence of MSP including retention cyst and mucosal thickening. Independent
Samples t-test and Pearson Chi-Square were used to for statistical analysis.Results: No
statistically significant difference was observed between patients with and
without MSP in terms of ostium width (p=0.13). While the mean ostium width was
2.08 mm in the patient with MSP it was measured as 2.14 mm in patients without
MSP. For all patients examined, right and left ostiums mean widths were 1.97 mm
(Range 0.67-4.25) and 2.26 mm (Range 0.67-5.25), respectively. No significant
difference was observed in ostium width according to gender (p≥0.05). Among all
patients, 18.7% (n=26) had MSP; of these 10 were bilateral and 16 were
unilateral.

Conclusion: MSP is the
common finding in CBCT examinations and the results of this study showed that
MSP does not seem to be associated with the ostium width.
MODERN VIEW TO PITYRIASIS VERSICOLOR: SOME ASPECTS OF PATHOGENESIS AND CLINICAL FEATURES IN CONDITIONS OF TORRID CLIMATE
Authors:   Department of Dermatovenereology, Avicenna Tajik State Medical University, Dushanbe, Tajikistan, ABDULLOEVA M.A. , ZOIROV P.T. ,   Department of Dermatovenereology, Avicenna Tajik State Medical University, Dushanbe, Tajikistan
Published: December 2018

Objective: Identify perspiration, skin pH, and clinical features in patients with pityriasis versicolor in conditions of torrid climate. Methods: In the period of 2008-2011 years, there were 110 patients examined with the diagnoses of pityriasis versicolor (Pityrosporum) in the local clinical hospital No. 1, in Dushanbe.They were 63.6% men (70 persons), and 36.4% – of them women (40 persons), which part of them were rural residents 53.6%, and others were urban residents – 46.4%. The highest number of cases of diseases has mentioned with people in the age of 17 to 35 years (80.9%). Control group comprised to 30 healthy persons. The diagnosis of pityriasis versicolor was determined based on positive Besnier’s symptoms, Balzer tests, yellowish-brown fluorescence at Wood’s light, as well as revealing of a typical microscopic picture of “spaghetti and meatballs”. Colorimetric method was used to determine the skin pH. For quality assessment of perspiration intensity in patients with pityriasis versicolor was used perspiration indicator IIP-01. Results: Erythematic-squamosal form was the most frequent recorded forms (73.7%) among the 9 clinical types. The expanded version of the pityriasis versicolor with typical localization of the affected areas made 80.9%, hyperpigmental form prevailed over hypopigmental form. Rare atypical forms of the disease (white spot type, erythrasmoid, urticarioid, lichenoid, ring-shaped, obliterated) were recorded in 11.8% of cases. 20.9% of patients had atypical localization of the pathological disease process on the face skin, axillary cavities, inframammary crease, inguinal fold, clunis, genitals, poples, dorslims of hands. In comparison with healthy persons which indicates perspiration and pH indicators 51.8 mA±0,46 and 5,33±0,004, patients with pityriasis versicolor had higher perspiration and pH in all tested areas and made the average of 60.1 мА±0,2 and 6,23±0,003 accordingly. Conclusion: Pityriasis versicolor is clinically polymorphyc. Along with the frequent forms, there are atypical forms with unusual localization of the disease process that may lead to diagnostic errors. Increased perspiration in torrid seasons causes to shift the skin pH in terms of alkaline content, and creates favorable environment for dissemination of Malassezia furfur. Keywords: Pityriasis versicolor, perspiration, pH, clinical development, atypical form.
APPLIANCE OF MODERN INFORMATIVE TECHNOLOGIES IN MEDICAL POSTGRADUATE EDUCATIONAL PROCESS
Authors:   Avicenna Tajik State Medical University, Dushanbe, Tajikistan, Gulov Mahmadsho , Shermatov Dusnazar ,   Avicenna Tajik State Medical University, Dushanbe, Tajikistan, Sattorov Dalerdjon ,   Avicenna Tajik State Medical University, Dushanbe, Tajikistan, Kobilov Kobildjon
Published: December 2018

This paper work describes the methodically new informative technologies in the system of continuing medical education. Medical students are trained by means of the information computer technologies that should be adopted and applied in their future professional activity. Scientifically and methodically substantiated systems of basic education based on computer technologies are created, and access to the library, data of international research and achievements is simplified. The stability of the educational process is maintained by computer use in all subjects and disciplines of the educational process. Keywords: Education, information technologies, program, teaching effectiveness, stability.
ASSESSMENT OF PRENATAL CARE IN THE REPUBLIC OF TAJIKISTAN
Authors:   Department of Public Health and Medical Statistics with the course of History of Medicine at Avicenna Tajik State Medical University, Miraliev Salohiddin , Juraeva Nargis ,   Department of Public Health and Medical Statistics with the course of History of Medicine at Avicenna Tajik State Medical University, Komilov Ismoil ,   Department of Public Health and Medical Statistics with the course of History of Medicine at Avicenna Tajik State Medical University, Nuriddinova Nigora
Published: December 2018

Objective: Assessment of the access to prenatal care and identification of possible impediments. Methods: In August – October 2015, it was interrogated 960 of women, who have finished the pregnancy in maternity hospital or at home, with absence or participation of medical worker, in the Republic of Tajikistan. Also, 16 discussions were held in focus-group comprising representatives of various levels of medical aid in the fields and jamoats. Results: 99.1% of respondents were registered for prenatal care with minor variations between regions (RRS – 97.9%, and up to 100% in the Sogd Region and GBAO). In the members of registrants of prenatal care are 90.3% and registered in the first pregnancy trimester according to the country standards, and 9.7% were registered at a late gestation period. The part of researched women, who has never attended consultations and obstetrician-gynecologist medical checkup consisted 7%, which is connected to the absence of obstetrician-gynecologists at the level of healthcare facilities. Pregnant women aged under 24 in the first pregnancy trimester were registered more often than compared to women aged 35 and older (90.8% and 82% accordingly). Percentage of recently parouse of women, who received prenatal care from 1 to 3 times, which made 58%, and a few of two thirds of them, who recently parouse of women are also, received prenatal care more than 4 times. Conclusion: The research provided high number of coverage the prenatal care, although home deliveries and deliveries without health personnel support remains an urgent issue for the health system of Tajikistan. The reasons of uncoverage were called: residing abroad, late awareness of pregnancy, absence of necessity in prenatal care, financial and geographical accessibility. As recorded that the family practitioners were men, which was the main reason of the low usage of service of family experts. Keywords: Prenatal care, family doctors, obstetrician-gynecologists.
ESTIMATION OF ENDOSCOPIC SYNUSOTHOMY EFFICIENCY IN CHRONIC RHINOSINUSITIS WITH NASAL POLYPS BASED ON DATA OF ENT CLINIC OF PUBLIC INSTITUTION «NATIONAL MEDICAL CENTER» OF THE REPUBLIC OF TAJIKISTAN
Authors:   Otolaryngology Department at National Medical Centre, Ikromov Mahmadulo , Davlatov Diloshub ,   Otolaryngology Clinic of National Medical Centre, Nazirmadova Mohira ,   Children’s ENT Department at National Medical Centre, Abduhalilov Abduzokir ,   First Otolaryngology Department at National Medical Centre
Published: December 2018

Objective: To conduct a comparative analysis of the effectiveness of endoscopic and traditional surgeries in patients with chronic rhinosinusitis with nasal polyps. Methods: At the age of 21 to 65 years, 56 of patients with chronic rhinosinusitis with nasal polyps were diagnosed. Patients were divided into two groups: 1st group (31 patients – the main group), in which surgical interventions were performed endoscopically and 2nd group (25 patients – control group), in which patients underwent surgery using traditional methods. Results: The effectiveness of the method was estimated based on the relapse frequency of the patients who underwent surgery. Analysis of the long-term results showed that relapse of the disease was detected in 12.9% of the patients of the main group and 40% of the control group. Conclusion: The method of endonasal endoscopic rhinosinusotomy in chronic rhinosinusitis with nasal polyps proved to be more effective than traditional method of treatment. Keywords: Endoscopic sinusotomy, nasal polyps, maxillary sinusotomy, surgery.
MORPHOFUNCTIONAL AND CYTOCHEMICAL PARALLELS IN HEREDITARY HAEMOLYTIC ANAEMIA IN CHILDREN
Authors:   Department of Pediatric Diseases № 2 at Avicenna Tajik State Medical University, Davlatova Sohira , Ismoilov Komildjon ,   Department of Pediatric Diseases № 2 at Avicenna Tajik State Medical University, Muhitdinova Zumrad ,   Department of Pediatric Diseases № 2 at Avicenna Tajik State Medical University, Solieva Lola ,   Pediatrician at National Medical Center of the Republic of Tajikistan
Published: December 2018

Objective: To study metabolic alterations in the organisms of children with hereditary hemolytic anemia (HHA). Methods: Authors studied metabolic conditions in 54 children aged 3 to 15 years suffering from HHA: deficit of glucose-6-phosphate dehydrogenase, thalassemia, genetic microspherocytocis. Metabolism research was carried out based on electrocardiographic, echocardiographic, and cytochemical methods. Results: It has been established that 96.3% of children with HHA had the signs of myocardial dystrophy. Analysis of echocardiogram shows heart cavity dilation (primarily left heart) and lower ejection fraction (55.2±1.6%). Analysis of cytochemical status of peripheral blood lymphocytes shows arrest of activity of energetic metabolism enzymes – succinate dehydrogenase (up to 11.54±0.25) and alpha-glycerophosphatedehydrogenase (up to 5.37±0.21). Conclusions: Results of performed laboratory and instrumental research methods show crude metabolic disturbances in children with HHA explained by the chronic hemic hypoxia, hemosyderosis of internals, and reduced activity of intracellular dehydrogenase. Keywords: Hereditary hemolytic anemia, hypoxia, myocardial dystrophy, metabolic disorders.
ANTIOXIDANT DEFENSE AND PECULIARITIES OF LIPID PEROXIDATION IN CHILDREN WITH BRONCHIAL ASTHMA
Authors:   Department of Pediatric Diseases № 2 at Avicenna Tajik State Medical University, Ismoilov Komildjon , Saburova Anna ,   Department of Biochemistry at Avicenna Tajik State Medical University, Sharipova Mavluda ,   Avicenna Tajik State Medical University
Published: December 2018

Objective: To research peculiarities of the lipid peroxidation and antioxidant system in children with bronchial asthma.Methods: It has taken the results of the research in 56 children aged from 5 to 14 years, who suffered with bronchial asthma (BA). Along with the general clinical examination, spirometry were used to identify respiratory function, and malondialdehyde (MDA) and superoxide dismutase contents in blood serum were analyzed. Results: Spirometry in all BA patients from attack of disease up to attack-free interval showed increasing of forced expiratory volume in 1 second (from 61.5±3.70% to 84.3±5.33%) and maximum voluntary ventilation (from 59.1±4.21% to 81.7±6.31%), and decreasing of residual volume (from 117.4±6.01% to 93.1±5.25%) . Biochemical studies revealed increase in the content of MDA (3.2±0.04), reduced activity of superoxide dismutase (10.7±0.2) and reduced content of ascorbic acid (57.6±0.28) in blood serum in children with BA. Conclusion: At the time of attacks in children lipid peroxidation processes are intensified and followed by increasing development of lipid peroxidation products (MDA), depletion of antioxidant system in blood serum, lower activity of superoxide dismutase, and increased sialic acid, which facilitates development of immune-inflammatory process in the bronchopulmonary system. Administration of Mexidol in children with BA led to earlier elimination of the key clinical and paraclinical implications such as: elimination of asthma attacks, disappearance of pulmonary rale, improved respiratory function parameters, and indicators of lipid peroxidation and antioxidant system in the blood serum. Keywords: Bronchial asthma, children, lipid peroxidation, antioxidants.
COURSE OF PREGNANCY IN WOMEN WITH VARICOSE DISEASE
Authors:   Local Maternity Hospital № 2 of the Dushanbe City Health Department, Marizoeva Mahina , Nematzoda Okiljon ,   Republican Scientific Center for Cardiovascular Surgery, Sultanov Javli ,   Avicenna Tajik State Medical University, Nazirova Gulnora ,   Local Maternity Hospital № 2 of the Dushanbe City Health Department, Ismatova Umiya ,   Local Maternity Hospital № 2 of the Dushanbe City Health Department, Bobdzhonova Oksana ,   Department of Obstetrics and Gynecology № 2, Avicenna Tajik State Medical University
Published: December 2018

Objective: Evaluation of the influence of varicose disease on the course and outcome of pregnancy. Methods: A comparative analysis of the pregnancy course was carried out in 24 women with varicose disease (the main group) and 24 pregnant women without it (control group). Both groups for age and pregnancy were comparable. The average age of women in both groups was 27.2± 3.1 years. Criteria of exceptions from the groups were preeclampsia and concomitant severe extragenital diseases. According to the clinical classification of CEAP, 20 patients had clinical grade II (C2), in 4 patients – clinical class III (C3) of chronic venous insufficiency. The combined varicose veins of great saphenous vein and its inflows, the veins of the vulva and the vagina were noted in 10 (41.7%) patients, isolated expansion of the trunk of the great saphenous vein and its inflows in 12 (50%) pregnant women, and pelvic congestion syndrome, dilatation of great saphenous vein and veins of the external genitals – in 2 (8.3%) cases. Results: At the end of the second trimester, 10 (41.7%) of the pregnant (main group) had dysuric disorders, whereas, in the control group only 1 (4.2%) observed these events. The incidence of placental insufficiency in patients of the main group (n = 12; 50%) was higher than in the control group (n = 1; 4.2%). The threat of interrupt pregnancy in the main group was registered in 14 (58.3%) cases, in the control group – only in 1 (4.2%) patients (p>0.05). The intrauterine growth retardation of a fetus was noted in 3 (12.5%) patients of the main group. In the main group, hydramnion were in 4 (16.7%) patients, whereas in the pregnant women of the control group, it occurred only in 1 (4.2%) cases (p> 0.05). In 4 (8.3%) patients of both groups, there was an edematous variant of gestosis, with a significant difference: in 3 (12.5%) patients in the main and in 1 (4.2%) control groups. Conclusion: The varicose disease leads to an increase in the development of various severe complications of gestation, which requires a comprehensive and timely correction. Keywords: pregnancy, varicose veins, threat interruption of pregnancy, intrauterine growth retardation of fetus, outcomes.
APPLICATION OF A TWO-STEP SCREENING SYSTEM IN COMPLEX EVALUATION OF PSYCHOSOCIAL STATUS IN PATIENTS WITH CORONARY HEART DISEASE
Authors:   Coronary Heart Disease and Atherosclerosis Department, National Center of Cardiology and Internal Diseases named after academician Mirsaid Mirrakhimov, Zalesskaya YuIiana
Published: December 2018

Objective: To study the features of the clinical and psychosocial profile using a two-step screening system in patients with coronary heart disease (CHD). Methods: In 115 patients with the stable CHD, conducted a general clinical examination with an assessment of the psychosocial status using the European Society of Cardiologists Questionnaire, the scales of the anxiety and depression of Hamilton, and the DS-14 questionnaire. Results: Analysis of the clinical status revealed a severe course of CHD in more than 40% of patients prevailing conditional risk factors (arterial hypertension, obesity, dyslipidemia), as well as low adherence to medicamentous therapy (statins, nitrates, calcium blockers, diuretics) and interventional procedures. The psychological status of those surveyed was characterized by a high rate of hostility (36.5%), personality type D (29.5%), anxiety (16.5%) and depression (6.9%), low socioeconomic status (6.9%), stress at work and in family life (6%). Conclusion: The two-step screening system with application of European Society of Cardiologists Questionnaire, Hamilton’s anxiety and depression scales, DS-14 questionnaire are recommended to use for well-timed verification of psychosocial risk factors in coronary heart disease patients with the aim to detect existing barriers to treatment and to optimize treatment and medioprophylactic measures. Keywords: Coronary heart disease, psychosocial factors.
CASE OF CONTACT ALLERGIC DERMATITIS INDUCED BY BLACK SEED OIL
Authors:   Department of Dermatovenereology, Avicenna TSMU, Abdieva Dilbar , Hayot Aliev ,   Department of Dermatovenereology, Avicenna TSMU, Valieva Mukhabbat ,   Department of Dermatovenereology, Avicenna TSMU, Dyrda Nina ,   Department of Dermatovenereology, AvicennaTSMU
Published: December 2018

In connection with increased popularity the usage of phytogenic medicaments, in the therapy of a variety diseases of a population in our region is widespread the oil of black seed (also known as caraway seeds). After the usage of black seed oil, there was a case described contactallergic dermatitis where it caused irritation. According to the recommendation of the doctor, the patient applies it in the form of tampons and lubricates the oil by her own to the inner surface of the thighs. A few days later, polymorphic rashes appeared on the skin, accompanied by oedema, itching, pain, burning and temperature. Based on clinical presentation and data of anamnesis set the diagnose «Contact allergic dermatitis, bullous form». The patient received general and local therapy. The patient with clinical improvement was discharged under the supervision of a dermatologist.
THE FIRST EXPERIENCE OF USING SILICONE IMPLANTS IN THE AUGMENTATION GLUTEOPLASTY IN TAJIKISTAN
Authors:   Department of Reconstructive Surgery of Republican Scientific Center for Cardiovascular Surgery, Khodzhamuradov Gafur , Ismoilov Mukhtordzhon ,   Department of Reconstructive Surgery of Republican Scientific Center for Cardiovascular Surgery, Saidov Mahmadullo ,   Department of Reconstructive Surgery of Republican Scientific Center for Cardiovascular Surgery, Shaymonov Aziz ,   Department of Reconstructive Surgery of Republican Scientific Center for Cardiovascular Surgery
Published: December 2018

The article describes the first experience of the use of silicone gluteal implants with the achievement of the aesthetic effect in 2 young patients aged 24 and 30 years. After a careful individual conversation, the method of placement in each case, there would be a combined procedure: in one observation – directly by gluteal muscle fascia, in the other – a submuscular position. The article notes that regardless of the method of implant placement, in both cases the optimal result was obtained, although there were certain features during the operation and in the postoperative period.
TOTAL CARDIOVASCULAR RISK – A NEW APPROACH FOR PREDICTING STROKE
Authors:   Department of Neurology and the Fundamentals of the Medical Genetics, Avicenna TSMU, Rakhmonov Rakhmatullo , Todzhiddinov Todzhiddin ,   Department of Neurology and Fundamentals of the Medical Genetics, Avicenna TSMU, Isoeva Manizha ,   Department of Neurology and the Fundamentals of the Medical Genetics, Avicenna TSMU, Zuurbekova Diloro ,   Department of Neurology and the Fundamentals of the Medical Genetics, Avicenna TSMU
Published: December 2018

Objective: Assess the cumulative risk of stroke among the working population of Dushanbe. Methods: The territory accepted the 6th Department of the Local Health Center № 1, Dushanbe, in 2014-2015 held continuous screening of discovery populations of persons aged 40-59. For integrated assessment of the total risk of stroke, both the total cardiovascular risk scale «SCORE» and the stroke risk scale «Stroke Riskometer™» were used. Results: It is revealed that investigated populations there is a combination of 2-4 risk factors. Based on the results of the SCORE scale in groups of very high and high risk turned out to be a total of 0.6% of persons aged 40-59 years. When the using similar the principle of stratification according to the scale «Riskometer™ stroke» in the same sample, revealed a significantly higher percentage of people with a high and very high risk of stroke – 15.6%. The use of «Stroke Riskometer™» allowed to estimate the average values of the 10-year risk of stroke, in both absolute and relative values. Conclusions: Estimating the cumulative risk of stroke with the help of special scales is a valid way to proper control of risk factors for its development.Keywords: Cumulative risk, stroke, prevention, Stroke Riskometer™
INVESTIGATION OF CALCIUM-PHOSPHORIC EXCHANGE IN WOMEN WITH THE MENOPAUSE STATE SUFFERING FROM OSTEOARTHROSIS AND CONCOMITANT OSTEOPENIC SYNDROME
Authors:   Pyatigorsk State Scientific Research Institute of Balneology, Kaysinova Agnessa , Lepshokova Amina ,   Pyatigorsk Clinic of Pyatigorsk State Scientific Research Institute of Balneology, Menshikova Tatyana ,   Department of the Revival Rheumatology, Pyatigorsk Clinic of the Pyatigorsk State Research Institute of Balneology, Akhkubekova Nelly ,   Pyatigorsk Clinic of the Pyatigorsk State Research Institute of Balneology, Cherevashchenko Lyubov ,   Pyatigorsk Clinic of the Pyatigorsk State Research Institute of Balneology, Mallaeva Raziyat ,   Department of Clinical Pharmacology of the Dagestan State Medical University
Published: December 2018

Objective: To study changes in calcium-phosphorus metabolism, bone metabolism and mineral bone density in osteoarthritis with the concomitant osteopenic syndrome in women with the menopause state. Methods: We examined 40 women in the state of menopause (50-60 years), patients with osteoarthrosis of the hip joints, with a duration of disease of 3-5 and more years (the main group), and 20 healthy women of the same age (control group).Results: An increase (p 0.05) of the serum level of the C-terminal telopeptide of type I collagen, a marker of bone resorption, a predominance speed of bone resorption rate over bone formation, while no significant deviations in the level of phosphatemia and calcemia were observed with a tendency to decrease activity of alkaline phosphatase and the level of osteocalcin – markers of bone formation in serum. In addition, osteopenia has been noted in various parts of the skeleton: in the spine with a predominantly trabecular type of bone structure. onclusion: The revealed multiple correlation relationships of the main characteristic indicators of osteoarthrosis with markers of bone resorption once again testify the comorbidity of osteoarthritis with osteoporosis. Keywords: Osteoarthritis, osteopenic syndrome, calcium-phosphorus metabolism, bone metabolism, menop
CAUSES OF KIDNEY TRANSPLANT DYSFUNCTION AND METHODS OF ITS CORRECTION
Authors:   Department of General Surgery № 1, Avicenna TSMU, Gulov Mahmadshoh , Pirov Bakhtiyor ,   Department of Transplantology, Belarusian Medical Academy of Postgraduate Education
Published: December 2018

The severity of the ischemia-reperfusion injury, the prognosis of survival, and the duration of renal allograft functioning have significant value. The use of new non-invasive methods for diagnosis of renal allograft dysfunction and the complex use of various drugs to improve its function create the prerequisites for preventing ischemia-reperfusion injury.
PLACE AND VALUE OF ENDOVASCULAR AND HYBRID TECHNOLOGIES IN TREATMENT OF LOWER EXTREMITY PERIPHERAL ARTERY DISEASE
Authors:   The Republican Scientific Center for Cardiovascular Surgery, Mukhammadieva Khotira Sukhrobdzhanovna , Gaibov Alidjon Djuraevich ,   Department of Surgical Diseases № 2, Avicenna Tajik State Medical University, Baratov Alisher Kenjaevich ,   Republican Scientific Center for Cardiovascular Surgery, Kalmykov Egan Leonidovich ,   Division of Science and Innovation, Avicenna Tajik State Medical University, Nematzoda Okildjon ,   The Republican Scientific Center for Cardiovascular Surgery, Rahmonov Dzhamakhon Ahmedovich ,   Director of the Republican Scientific Center for Cardiovascular Surgery
Published: December 2018

Objective: The article analyzed the possibilities of hybrid and endovascular operations in the treatment of patients with chronic ischemia of the lower limbs. The analysis of the literature shows that at the present stage these interventions are being applied more and more often, often being an alternative to traditional operations. Most researchers have proven that when performing hybrid and endovascular operations, a low incidence of cardiovascular events and infectious complications is noted, and in most cases, it is possible to save the limb. However, the effectiveness of this or that method of treating peripheral artery disease of the lower limbs depends both on the degree of limb ischemia and anatomical level of the lesion where performed revascularization. To date, the literature on this issue does not have a definitive answer regarding the priority in choosing the method of revascularization of the limb. This is primarily due to the type of arterial lesion, the level of occlusion or stenosis, and the presence of severe comorbid status, the experience of the surgeon and the technical equipment of the clinic. Keywords: Atherosclerosis , lower limb ischemia , hybrid operations, angioplasty, stenting , amputation .
A HÀM LƯỢNG THỦY NGÂN TRONG THAN SỬ DỤNG TẠI MỘT SỐ NHÀ MÁY NHIỆT ĐIỆN Ở VIỆT NAM
Authors: Khải Nguyễn Mạnh
Published: December 2018

Than nội địa sử dụng cho các nhà máy nhiệt điện (NMNĐ) của Việt Nam hiện nay là than cám 5,6 theo TCVN 8910:2015, hàm lượng chất bốc thấp, độ tro cao. Ngoài các thành phần kim loại, oxyt kim loại đã xác định hàm lượng có mặt trong than phổ biến trước đây hàm lượng thủy ngân cũng bước đầu được nghiên cứu, tìm hiểu. Qua phân tích, hàm lượng thủy ngân trong than nguyên liệu các NMNĐ của Việt Nam xác định giao động trong khoảng từ 0,06-0,14ppm, cá biệt có mẫu đạt giá trị 0,82ppm. Giá trị hàm lượng này ở mức thấp khi so sánh với các than cùng chủng loại tại Trung Quốc và một số nước. Với sự có mặt của thủy ngân trong nguyên liệu, theo nguyên lý bảo toàn vật chất thủy ngân sẽ xuất hiện trong các sản phẩm quá trình cháy NMNĐ bao gồm cả pha rắn, lỏng, khí với mức độ phân bố khác nhau tùy điều kiện cháy. Theo đánh giá sơ bộ, nguồn than từ các mỏ khu vực Mông Dương, Uông Bí, Vàng Danh, Khe Chàm, Nam Mẫu, Cao Sơn tuy có hàm lượng thủy ngân ở ngưỡng thấp nhưng cao hơn sơ với các mỏ cung cấp than antracide khác trong nước cũng như than nhập khẩu hiện tại.
Evaluation of GSMaP Satellite Precipitation Over Central VietNam in 2000-2010 Period and Correction Ability
Authors: Thanh Hang Vu , Thi Thanh Nga Pham , Thanh Hà Pham
Published: December 2018

Abstract: Daily/Monthly precipitation of GSMaP is compared with observation at 10 stations over Central VietNam in 2000-2010 period. Evaluation indices used in this study include correlation coefficient (r), relative bias (B), probability of detection (POD) and false alarm ratio (FAR). The results show that the agreement of the first rainy month over 100mm and the maximum rainy month between GSMaP and observation, however, the duration of rainy months over 100mm of GSMaP is shorter than that of observation. GSMaP precipitationoften underestimates compared to observation in October-December  at almost stations.It can be seen that monthly correlation coefficients are often positive at almost stations when evaluating daily precipitation, the lower values normally are found in January and February. Positive relative biases are observed in April-September at most of North Central stations, while those often occur in July-September at South Central stations. Negative relative biases can be found in October until March of next year at almost stations. The good POD and FAR values are given at 0-6mm/day threshold and the worse values are found at 6-16mm/day threshold. After applying correction methods, the GSMaP precipitation is much better agreement with observation, especially in underestimated rainy months.

      Key words:Precipitation, GSMaP, evaluation, correction.
Phân biệt mô hình hiến pháp và phân loại hiến pháp
Authors: Nguyen Quang Duc
Published: December 2018

Bài viết chỉ ra khả năng nhầm lẫn giữa phân loại hiến pháp và mô hình hiến pháp. Trong khi phân loại hiến pháp dựa trên sự phân biệt hình thức hiến pháp (cương tính – nhu tính, thành văn – bất thành văn) thì mô hình hiến pháp là kết quả của sự phân hóa quan niệm về hiến pháp trong tiến trình của lịch sử lập hiến. Theo đó, sự phân hóa quan niệm về hiến pháp là một tiến trình tạo ra sự thay đổi hiến pháp xét theo quan điểm thực chất. Tiến trình này thường xảy ra khi các cấu trúc chính trị - xã hội thay đổi, dẫn đến các đặc điểm và nội dung phản ánh của hiến pháp thay đổi, kết quả hình thành nên một mô hình hiến pháp mới. Từ quan điểm này, tác giả sẽ khảo sát và chỉ ra những đặc điểm và nội dung của các mô hình hiến pháp đã có trong lịch sử lập hiến, đồng thời có sự so sánh với các quan điểm đang hiện hành trong giới nghiên cứu.
CẦN CỤ THỂ HÓA QUY PHẠM CỦA HIẾN PHÁP NĂM 2013 (đoạn 2 khoản 2 Điều 119) VÀ MỘT SỐ LUẬN ĐIỂM TẠI HỘI NGHỊ TRUNG ƯƠNG TÁM (Khóa XII) CỦA ĐẢNG VÀO CUỘC SỐNG
Authors: Lê Văn Cảm , Nguyễn Cảnh Hợp
Published: December 2018

Trên cơ sở các luận điểm Đảng về kiểm soát quyền lực (KSQL) nhà nước nhằm bảo vệ Hiến pháp (BVHP) của 03 Đại hội (X, XI, XII), Hội nghị TW tám (khóa XII, cũng như  của cố Tổng bí thư Đỗ Mười về sự cần thiết phải xây dựng Tòa án Hiến pháp ở nước ta, bài viết đề cập đến sự phân tích khoa học những vấn đề về KSQL nhà nước và đưa ra những kiến giải lập hiến và lập pháp cụ thể đối với cơ chế BVHP bằng nhánh quyền lực tư pháp ở Việt Nam trong giai đoạn xây dưng Nhà nước pháp quyền hiện nay
PEROLEHAN TANAH OBYEK REFORMA AGRARIA (TORA) YANG BERASAL DARI KAWASAN HUTAN: PERMASALAHAN DAN PENGATURANNYA
Authors: Nurlinda Ida
Published: December 2018

Agrarian reform is in essence a government policy attempting to restructure land ownership and control.  President Jokowi’s government set the target of 9 million hectares of which 4.1 million hectares is classified formerly as forest land.  It was and still is no easy task. But this agrarian reform, involving mostly change of ownership of forest land and redistribution, is considered necessary as part of effort to guarantee society’s welfare. This article purports to analyse the legal framework of forest land release and related problems. To do that a juridical dogmatic approach will be used and with secondary data as primary source of information.  The main finding of this research is that real problems arises in the context of implementing the Environmental and Forest Ministerial Decree Number180/Menlhk/Setjen/kum.1/4/2017 which provides guidance in regard the procedure and requirements to be met for forest land release. In the case that in the process, land ownership dispute arose, stakeholders should seek guidance from Presidential RegulationNumber  88/2017 regarding Settlement of Land Management/Ownership in Forest Land.
IMPLIKASI DOKTRIN “FAIR USE” TERHADAP PENGEMBANGAN ILMU PENGETAHUAN OLEH AKADEMISI (DOSEN) ATAU PENELITI DALAM PERSPEKTIF HUKUM HAK CIPTA
Authors: Sudjana Sudjana
Published: December 2018

In this article the author discusses the fair use (Art. 43-49 Law 28/2014 re. copyright) in relation scientific work performed by lecturers and researchers.  This legal discourse in the field of copyright law will be performed using a juridical normative approach. One important finding is that the fair use doctrine allows lecturers and researchers to utilize copyright protected work from others – in the name of scientific progress or educational purposes – without having to obtain prior consent or license. Nonetheless, user of copyright protected works must pay attention to reasonable interest of copyright holder, the meaning of which is left to legal practice.
SISTEM EKONOMI INDONESIA DALAM PERSPEKTIF PANCASILA DAN UUD 1945
Authors: Pratama Agung Rifqi
Published: December 2018

The focus of this article, using a juridical normatif and philosophical approach, is in tracking how Article 33 of the Indonesian Constitution is understood and how the Pancasila economic system (based on the five tenets of the State’s ideology) is being implemented by a number of exisitng economic policies. While the Article should be regarded as the embedodiment of Indonesian economic policy, it cannot be denied that the understanding of  it evolved and changed following the 4thamendment to the Constitution. It is observed that the 4thamendment to the 1945 Constitution have had a great impact on the direction taken by the Indonesian economic policy makers.  In using a juridical normative approach we are forced to take the position that Pancasila economic system as found in the Constitution should be followed by the letter in real economic policy making. On the other hand, just to do that, we cannot but realize the need for the existence of government political will.
The Anti-corruption Institutions in South Africa: A Panacea to Governance Ills?
Authors: Hlongwane Paulus
Published: December 2018

The purpose of this article is to assess the role played by the South African anti-corruption institutions in addressing corruption in government departments. The negative impact of corruption on the effectiveness and efficiency of the service delivery by government departments necessitates an examination of the role of the anti-corruption institutions. For the purposes of this article, a review of scholarly published articles, newspaper articles, case law and annual reports of the anti-corruption institutions in South Africa was undertaken. With regard to the anti-corruption institutions, it is has not yet been established whether they are operating free of political interference in South Africa. This article contends that the anti-corruption institutions should be sufficiently resourced and funded by the government to enable them to deal effectively with the corrupt activities that pervade government departments. Moreover, the anti-corruption institutions should be able to perform their functions without any political interference that could possibly influence their proper functioning negatively.
DETECTION OF THE INFLUENCE OF TRANSCRANIAL ELECTROSTIMULATION ON THE STESS RESISTANCE OF STUDENTS BY THE TEST OF T. HOLMES AND R. RAHE
Authors: Kade A. H. , Achedzhak-Naguze S. K. , Tereschenko O. A.
Published: December 2018

Aim.The study was designed to establish the influence of transcranial electrostimulation on the stress tolerance of students by the method of T. Holmes and R. Rahe.

Materials and methods.The observations were made on 127 students aged 19-22. They were 50 boys and 77 girls. The students were divided into the main group (78 people) and the comparison group (49 people). Transcranial electrostimulation was carried out for the students of the main group: 2 sessions per week and 5 sessions per week. Stress resistance was assessed by the test of stress resistance and social adaptation of T. Holmes and R. Rahe before the course of transcranial electrostimulation and after it. The level of stress resistance was determined in the comparison group within the same time frame. Transcranial electrostimulation (TES) was performed by the “Transair-03” apparatus on the testees in the sitting position. The value of the pulse current of 3 mA, frequency 7.5 Hz was used. The exposure time was 30 minutes. The results of the study were processed with the help of the “Statistika 6.0” computer program.

Results.At the end of the school year, students had low, threshold and high levels of stress resistance. These levels of resistance to stress remained in those individuals who did not undergo transcranial electrostimulation, and also in students who had 2 transcranial electrostimulation sessions per week. After 5 sessions of transcranial electrostimulation per week, students had a threshold and high levels of stress resistance; there was no low level. After 5 sessions of transcranial electrostimulation the total number of points in students with a threshold level of stress resistance statistically decreased by 11,0% in comparison with the initial result. The total number of points after transcranial electrostimulation in students with a high level of stress resistance statistically decreased by 8,4%.

Conclusion.The results indicate an increase in the level of students' stress tolerance and the effectiveness of transcranial therapy for at least 5 sessions per week.
MORPHOGISTOSCHEMICAL CHARACTERISTIC OF THE IMPLANT FROM POLYLACTIC ACID
Authors: Mogilnaya G. M. , Fomicheva E. V. , Blatt J. E.
Published: December 2018

Aim.The study was conducted for the characteristics of the morphoimmunohistochemical status of the implant from polylactic acid (PLA) located in the dermis.

Materials and methods.The study was performed on rats (30 individuals) with subdermal administration of the drug in a volume of 0,05 ml. The results were evaluated after two weeks, 1 and 2 months after the injection. The sections were stained with hematoxylin and eosin, according to Van Gieson, with the help of Mallory and Masson reaction. Collagen fibers were studied after the staining with picrosirius red under polarized light. Monoclonal antibodies of CD 68 and antibodies to vimentin were used to determine the expression of immunohistochemical markers.

Results. It is shown that the rate of collagen synthesis varies in different parts of the dermis. There is a sharp increase in the volume of the fibrous component around the implant, and there is only a tendency to increase in the synthesis in the implant itself. In this case, the increase in the volume of the extracellular matrix is associated with type I and III collagen.

Conclusion.The detected activation of collagen synthesis by fibroblasts can be used as a regulator of the volume of the matrix, which is very important for the modern regenerative medicine.