bluuebunny/crossref_metadata_2025 huggingface dataset:
Motricidade humana: o itinerário de um conceito
Authors: Sérgio Manuel
Published: April 2022

Motricidade humana: o itinerário de um conceito
ResumoSão muitos os que se licenciaram em Educação Física e relativizam a fixidez do nome que pretende definir a sua profissão. Com efeito, nenhum deles se vê cartesianamente centrado na educação de físicos. A passagem do físico à motricidade que não confundo com movimento tão-só (ao invés de alguns estudiosos), surge como a mudança de lugar do corpo humano, num espaço e tempo determinados, com as características de um processo objetivo. Procuro fundamentar a motricidade humana na intencionalidade e no mundo da vida. Ao anunciar-se um novo paradigma (ação intencional e solidária de transcendência), a Ciência da Motricidade Humana procura servir também os anseios de todos os marginalizados pela sociedade injusta. Verdadeiramente, o Ser Humano é ser-ao-mundo-com-outrem. E tudo isto, em busca da transcendência, da superação, da plenitude, do ser-mais.Palavras-chave: Ciência da Motricidade Humana. Intencionalidade. Transcendência.
Human motricity: the itinerary of a concept
AbstractThere are many who graduated in Physical Education and relativize the fixity of the name that intends to define their profession. Indeed, none of them sees itself as being Cartesian focused on the education of physicists. The passage from the physical to the motricity, which I do not confuse with movement only (instead of some researchers), appears as the change of place of the human body, in a determined space and time, with the characteristics of an objective process. I try to ground human motricity in intentionality and in the world of life.
By announcing a new paradigm (the intentional and solidary action of transcendence), the Science of Human Motricity also seeks to serve the aspirations of all those marginalized by an unjust society. Truly, the Human Being is to-be-to-the-world-with-others. And all this, in search of transcendence, overcoming, fullness, from of to-be-most.Keywords: Human Motricity Science. Intentionality. Transcendence.
Motricidad humana: el itinerario de un concepto 
ResumenSon muchos los que se gradúan en Educación Física y relativizan la fijeza del nombre que pretende definir su profesión. De hecho, ninguno de ellos se ve a sí mismo como cartesiano centrado en la formación de físicos. El paso de lo físico a la motricidad, que no confundo sólo con movimiento (a diferencia de algunos estudiosos), aparece como el cambio de lugar del cuerpo humano, en un espacio y tiempo determinados, con las características de un proceso objetivo. Intento fundamentar la motricidad humana en la intencionalidad y en el mundo de la vida. Al anunciar un nuevo paradigma (la acción intencional y solidaria de la trascendencia), la Ciencia de la Motricidad Humana también busca servir las aspiraciones de todos aquellos marginados por una sociedad injusta. Verdaderamente, el Ser Humano es ser-al-mundo-con-otren. Y todo ello, en busca de la trascendencia, la superación, la plenitud, del ser-más.Palabras clave: Ciencia de la Motricidad Humana. Intencionalidad. Trascendencia.
REVISTA JORNAL DAS MOÇAS E A FORMAÇÃO PARA UM COMPORTAMENTO IDEAL FEMININO (1930-1945)
Authors: Albuquerque Dálete Cristiane Silva Heitor de , Sá Elizabeth Figueiredo de
Published: April 2022

O presente artigo visa analisar as imagens, seções, propagandas e suplemento veiculados na
revista Jornal das Moças voltados para a educação do comportamento feminino, conforme a representação
hegemônica presente na sociedade. O período delimitado de 1930 a 1945, justifica-se por ser um período
de governo ditatorial, de Getúlio Vargas e, por contraditoriamente ser um período de muitas intervenções
e manifestações femininas em prol do direito de escolarização, trabalho e cidadania. O percurso
metodológico foi realizado utilizando de análise textual de 11 edições da revista publicadas na Era Vargas.
O conceito de representações de Roger Chartier subsidiou as análises. Como resultado foi possível
compreender que a revista se voltava ao público feminino ensinando-o, a partir de inserções que foram
formando, gradativamente, manuais de civilidade às leitoras, a agir nos espaços de sociabilidade,
principalmente em seu lar com o seu marido.
ORGANIZATIONAL, METHODOLOGICAL AND ECONOMIC IMPERATIVES OF DEVELOPING AN INNOVATION STRATEGY OF A REGION'S SUSTAINABILITY ON THE BASIS OF INTELLECTUAL CAPACITY BUILDING
Authors: Pidvalna Oksana , Kachala Tamara , Romashchenko Kateryna
Published: April 2022

The purpose of the paper is the research of organizational, methodological and economic imperatives of developing an innovation strategy of sustainability for a region on the basis of intellectual capacity building. Methodology. Methods of scientific analysis and synthesis, structural, factor, system and functional analysis, methods of economic and statistical analysis were used as main methods in this research. In addition, we used special methods of complex economic analysis: monographic method during the research on the specific features of intellectual capacity building, historical method during the research on principles and factors of a region's intellectual capacity building and development strategy, abstract and logical methods in defining modern requirements for the intellectual potential of a region, systematic and comprehensive methods in formulating a model of economic sustainability of intellectual capacity development in a region, structural objectives to develop the strategic mechanism of intellectual capacity development in a region. Results. An innovation strategy of a region economic sustainability is proposed in this paper. The strategy is a scheme of achieving significant long-term competitive advantages and the main tool of a sustainable region development that creates a possibility for the efficient use of intellectual, productive, technological and market resources. Structural interconnection of resource components of innovational capacity in the system of a region strategic sustainability support is analyzed. The research presents the algorithm of innovation strategy development in the system of a region strategic sustainability support. An integrated benchmark and indicator system that helps to choose a certain innovation strategy of region development is characterized. The mentioned criteria and indicators provide more rational and effective choice of innovative behavior. We proposed principal directions of investment in the intellectual capacity of a region and developed a scheme for evaluation and selection of investing alternatives for the intellectual capacity of a region. Practical implications. The proposed organizational and economic tools allow implementing relevance and efficiency of intellectual capacity management in order to ensure its strategic sustainability. Value/originality. The acquired results show a theoretical base of organizational, methodological and economic imperatives of developing an innovation strategy of region sustainability and the growth of the regional economics.
INNOVATIVE CHANGES IN FINANCIAL AND TAX SYSTEMS IN THE CONDITIONS OF DIGITAL TRANSFORMATION
Authors: Manzhura Oleksandr , Pochenchuk Galyna , Kraus Nataliia
Published: April 2022

The purpose of the research is to present the features of innovative changes in financial and tax systems in terms of digital transformation as a foundation to build a new quality of economic system in terms of virtual mobility and financial technologies that change business in the direction of its electronic direction. The object of the scientific research is the process of digitizing innovative changes in financial and tax systems in terms of virtual mobility, which has every chance to become a decisive step in implementing digital development strategy of Ukraine through the development of digital financial instruments, digitized financial de-velopment institutions, smart services and efficient defining a new quality of management of financial and tax systems. Methodology. By relying on compara-tive-retrospective analysis, synthesis, and system method, the digitalization of innovative changes of financial and tax systems is investigated. It determines the new quality and format of work of financial development institutions in the times of deepening virtual mobility. Comparative analysis was used to study the con-tent of regulatory and supervisory financial technologies, namely: RegTech, SupTech; the functions of financial system that reveal its role are indicated. The result of the article. Factors contributing to the development of financial system are presented; the authors give their vision of the content of non-financial com-panies that provide traditional financial services in virtual reality. The content of some innovative and digital changes in the Ukrainian tax system has been identi-fied and disclosed. Practical implications. It is argued that key innovative chang-es that need to be addressed in the context of reforming and digital transfor-mation of financial system have been revealed. Factors contributing to the devel-opment of financial system are presented. The peculiarities of digital initiatives that take place in the taxation system are indicated. Value/originality. In order to timely inform taxpayers in the media and on the web portal of the tax service, it is proposed to systematically covers main issues regarding the procedure for fil-ing tax returns, categories of taxpayers required to file reports, deadlines for such reporting, list of costs included as part of tax rebate. Payer Service Center should implement this awareness. Author’s vision of the content of practical work of non-financial companies providing traditional financial services in the conditions of virtual mobility is presented and thoroughly revealed.
IMPLEMENTASI MODEL PEMBELAJARAN SOMATIC-AUDITORY-VISUALIZATION-INTELLECTUALLY (SAVI) PADA PELAJARAN FIQIH DALAM MENINGKATKAN AKTIVITAS BELAJAR SISWA DI MTS HIDAYATUL HASAN BLUKON LUMAJANG
Authors: Ishari Nurhafid , Adela Ratna Nur
Published: April 2022

Era modernisasi saat ini, teknologi dunia pendidikan berkembang sangat pesat. Dengan berbagai model pembelajaran efektif dan menyenangkan salah satunya model pembelajaran SAVI (Somatic, Auditory, Visualization, Intellectually) yang merupakan model pembelajaran mengkolaborasikan gerakan fisik dan aktivitas intelektual siswa. Fokus masalah yang diteliti: Bagaimana implementasi model pembelajaran SAVI pada pelajaran Fiqih dalam meningkatkan aktivitas belajar siswa di MTs Hidayatul Hasan Blukon Lumajang?; Apakah model pembelajaran SAVI mampu meningkatkan aktivitas belajar siswa di MTs Hidayatul Hasan Blukon Lumajang?. Dari fokus tersebut menyimpulkan tujuan penelitian: Untuk mengetahui implementasi model pembelajaran SAVI pada pelajaran Fiqih dalam meningkatkan aktivitas belajar siswa; Untuk mengetahui model pembelajaran SAVI mampu meningkatkan aktivitas belajar siswa. Penelitian ini merupakan penelitian lapangan menggunakan metode kualitatif. Pengumpulan data melalui observasi langsung, wawancara, dokumentasi. Dianalisis deskriptif berupa penggambaran kejadian di lapangan. Kesimpulan penelitian; Implementasi model pembelajaran SAVI pada pelajaran Fiqih di MTs Hidayatul Hasan Blukon sangatlah diperlukan agar pembelajaran tidak monoton, membosankan dan akhirnya mampu membuat siswa tertarik mengikuti pembelajaran dengan maksimal; Dalam implementasi model pembelajaran SAVI pada pelajaran Fiqih di MTs Hidayatul Hasan ternyata mampu meningkatkan aktivitas belajar siswanya. Terlihat dari respon positif siswa yang biasanya mendengarkan materi sepanjang pelajaran, sekarang siswa dapat mempraktekkan, mudah memahami serta punya pengalaman langsung mengenai materi tersebut.
Uso de tecnologias educacionais como instrumento de cuidado ao cliente com lesões de pele
Authors: Cardoso Rachel da Silva Serejo , Sá Selma Petra Chaves
Published: April 2022

O uso das tecnologias vem crescendo consideravelmente ao longo dos anos, trazendo grandes possibilidadesde utilização de novos recursos nas práticas de cuidado e ensino de saúde. A Enfermagem, por sua vez, vemcrescendo e modificando sua prática de cuidado juntamente com o advento das tecnologias, seja ela dura, levedura ou tecnologia leve(1).Uma análise do conceito de tecnologias educacionais (TEs) em Enfermagem aplicada ao paciente mostrou que osatributos relacionados às TEs podem ser entendidos por: ferramentas, estratégias, abordagem inovadora, apoio, artefato, processos, promoção de saúde, processos educativos em saúde, interação, recurso, aquisição de competências,mediadora do conhecimento e útil para o cuidado(1).O enfermeiro tem um importante papel de educador, desta forma, deve desenvolver estratégia educativa quefacilite a aprendizagem significativa da equipe de enfermagem, do paciente portador de lesão de pele e sua família,acerca dos cuidados com a pele, principalmente no que tange os cuidados no domicílio(2).Enfatiza-se também a importância do enfermeiro no atendimento à população que recorre aos cuidados de saúde.Desta forma, o uso das tecnologias educacionais por enfermeiros pode contribuir para a efetivação da assistência,acompanhamento e orientação dos pacientes com lesão de forma inovadora e utilizando recursos de aprendizagemà distância(3).Torna-se um desafio termos enfermeiros cada vez mais aptos a utilizar as tecnologias educacionais para melhorar o processo de cuidado ao paciente e à família e implementar processos educativos inovadores(3). Vale lembrarque o cliente com lesão de pele tem suas características peculiares, o enfermeiro deverá ter conhecimento dosfatores envolvidos neste evento, deve-se levar em consideração, além dos fatores biológicos, os fatores biopsicossociais que poderão estar afetados, tanto na pessoa com lesão como em sua rede social, seja no âmbito hospitalarou na atenção básica(4).Infelizmente o conhecimento dos enfermeiros sobre cuidados com lesão de pele mostra-se um tanto incipiente.Um estudo recente de Portugal(2) objetivou identificar o conhecimento dos enfermeiros, não especialistas em estomaterapia ou dermatologia, acerca das lesões por pressão, concluindo que os enfermeiros não especialistas emestomaterapia ou dermatologia apresentaram conhecimento inadequado acerca das lesões por pressão. Este estudoaponta a necessidade educacional no que tange a temática.O uso das TEs para os cuidadores mostra-se eficaz no que concerne ao processo de orientação e informaçãoao cuidado(5), assim como para o profissional enfermeiro(3). Frente a isso, vos convido, profissionais de enfermagemao desafio do uso das tecnologias educacionais em sua prática de cuidado com os pacientes e sua família como umaferramenta importante no processo de cuidado, possibilitando a aprendizagem significativa dos planos de cuidado aocliente portador de lesão de pele.
A depressão pós-parto na perspectiva dos profissionais de saúde
Authors: Louzada Walquiria , Oliveira Adriane Maria Netto de , Silva Priscila Arruda da , Kerber Nalu Pereira Costa , Algeri Simone
Published: April 2022

O Objetivo é analisar o conhecimento de enfermeiros e médicos de duas maternidades da região sul do Brasil acercada depressão pós-parto. Trata-se de uma pesquisa qualitativa, cuja amostra constituiu-se por 11 profissionais de saúde,incluindo médicos e enfermeiros de duas maternidades do sul do Brasil, em 2016. Constatou-se que os profissionais dasaúde percebem a importância de seu papel na identificação, prevenção e tratamento da depressão pós-parto. Porém,ainda existem dificuldades para reconhecê-la, uma vez que não existe nos hospitais instrumentos específicos implementados que possam ajuda-los na identificação, bem como a capacitação sobre o tema. A identificação precoce dossintomas que norteiam o quatro patológico puerperal é de suma importância, pois quanto antes forem reconhecidosos indícios da doença, maiores serão os reflexos positivos que poderão ser oferecidos à assistência individual e familiarda puérpera.Palavras-chave: Depressão Pós-Parto; Enfermagem; Gravidez; Período Pós-PartoABSTRACTThe objective is to analyze the knowledge of nurses and physicians of two maternity hospitals in southern Brazil aboutpostpartum depression. This is a qualitative research whose sample consisted of 11 health professionals, includingdoctors and nurses from two maternity hospitals in the south of Brazil, in 2016. It was found that health professionalsperceive the importance of their role in identifying, prevention and treatment of postpartum depression. However,there are still difficulties to recognize it, since there are no specific instruments implemented in hospitals that can helpthem with the identification and training on the subject. The early identification of the symptoms that guide the fourpathological puerperal is of paramount importance, since the earlier the signs of the disease are recognized, the greaterthe positive reflexes that can be offered to the individual and family care of the puerperal.Keywords: Postpartum Depression; Nursing; Pregnancy; Postpartum Period
Perinatal Risk Factors for the Development of Neonatal Intraventricular Hemorrhage in Preterm Infants
Authors: Iwahata Yuriko , Hasegawa Junichi , Homma Chika , Iwahata Hideyuki , Furuya Natsumi , Kondo Haruhiro , Suzuki Nao
Published: April 2022

Background: To evaluate the impact perinatal factors closely related to the development of neonatal intraventricular hemorrhage (IVH) in preterm infants. Methods: A retrospective case-control study was performed on premature infants born in our perinatal center in 2014–2018. Neonates with IVH were age-matched with normal controls (1:5). Perinatal factors were compared between cases and controls. Results: Fourteen cases and 70 controls had a median of 26.5 (range 22–29) weeks gestational age. Significant difference was observed regarding the incidence of clinical chorioamnionitis (43% and 14%, p = 0.023) and the use of magnesium sulfate (MgSO4) (14% and 51%, p = 0.017). Adjusted odds ratios (95% confidence interval) were 8.3 (1.8–38) in clinical chorioamnionitis and 0.15 (0.03–0.76) in magnesium sulfate. Conclusions: Relevant perinatal factor of IVH in premature infants born before 30 weeks of gestation was strongly associated with clinical chorioamnionitis. Furthermore, MgSO4 exposure suggested a neuroprotective effect against IVH.
Labor induction: change of indications and outcomes over time and future trends — a retrospective analysis
Authors: Omerović Aida , Pajek Sandra , Anzeljc Veronika , Mujezinović Faris
Published: April 2022

Background: The purpose of this study was to evaluate the results of induction of labor over time in order to identify future trends. Methods: Data were collected from a national database for University Medical Center Maribor on the pregnant women demographics, the indications for labor induction, the process of induction and delivery, and the outcomes of delivery for periods 2011‒14 and 2015‒18. Results: In the second period (2015‒18), the rate of labor induction increased (14.7% vs. 19.0%, p < 0.00001), pregnant women were older (29.7 years vs. 30.0 years, p = 0.0018), were more frequently monitored in tertiary hospitals during pregnancy (40.6% vs. 80.7%, p < 0.00001), had hypertension in pregnancy (5.4% vs. 2.7%, p = 0.0002), and oligohydramnios (9.6% vs. 6.9% , p = 0.007). During labor, amniotomies (60.3% vs. 53.7%, p = 0.0004), umbilical cord prolapses (1.2% vs. 0.1%, p = 0.0003), meconium amniotic fluids (12.7% vs. 8.8%, p = 0.0008), pathological CTG tracings (15.2% vs. 8.4%, p < 0.00001) were less frequent. There were less episiotomies (37.4% vs. 29.1%, p < 0.00001), vacuum extractions (4.2% vs. 2.8%, p = 0.049), while the rate of caesarean sections remained constant (15.0% vs. 16.6%, p = 0.23). Conclusions: There is a tendency toward increased induction of labor (IOL) rates, probably related to higher average age of women, but with better delivery outcomes. Our findings reflect local practice and cannot be generalized.
Alterations in somatosensory, visual and auditory pathways in amyotrophic lateral sclerosis: an under-recognised facet of ALS
Authors: Chipika Rangariroyashe H. , Mulkerrin Grainne , Murad Aizuri , Lope Jasmin , Hardiman Orla , Bede Peter
Published: April 2022

Background: While amyotrophic lateral sclerosis (ALS) is widely recognised as a multi-network disorder with extensive frontotemporal and cerebellar involvement, sensory dysfunction is relatively under evaluated. Subtle sensory deficits have been sporadically reported, but there is a prevailing notion that sensory pathways may be relatively spared in ALS. Methods: In a prospective neuroimaging study we have systematically evaluated cerebral grey and white matter structures involved in the processing, relaying and mediation of sensory information. Twenty two C9orf72 positive ALS patients (C9+ ALS), 138 C9orf72 negative ALS patients (C9- ALS) and 127 healthy controls were included. Results: Widespread cortical alterations were observed in C9+ ALS including both primary and secondary somatosensory regions. In C9- ALS, cortical thickness reductions were observed in the postcentral gyrus. Thalamic nuclei relaying somatosensory information as well as the medial and lateral geniculate nuclei exhibited volume reductions. Diffusivity indices revealed posterior thalamic radiation pathology and a trend of left medial lemniscus degeneration was also observed in C9- ALS (p = 0.054). Our radiology data confirm the degeneration of somatosensory, visual and auditory pathways in ALS, which is more marked in GGGGCC hexanucleotide repeat expansion carriers. Conclusions: In contrast to the overwhelming focus on motor system degeneration and frontotemporal dysfunction in recent research studies, our findings confirm that sensory circuits are also affected in ALS. The involvement of somatosensory, auditory and visual pathways in ALS may have important clinical ramifications which are easily overlooked in the context of unremitting motor decline. Subtle sensory deficits may exacerbate mobility, contribute to fall risk, impair dexterity, and worsen bulbar dysfunction, therefore comprehensive sensory testing should also be performed as part of the clinical assessments in ALS.
Implantable Cardiac Defibrillator Lead Infective Endocarditis Due to Rothia Specie: A Rare Case in An Immunocompetent Man
Authors: Obi Chukwuemeka A. , Egbuche Obiora , Nwokike Shirley I. , Mezue Kenechukwu , Abe Temidayo , Bulsara Kishen , Olanipekun Titilope , Onuorah Ifeoma
Published: April 2022

Background: Rothia species are known to cause dental caries and periodontal disease, and infrequently cause native or prosthetic valve endocarditis mostly in immunocompromised persons. With an increasing use of implantable cardiac devices, early clinical suspicion and a rapid diagnosis of endocarditis is essential for optimal treatment to reduce complications and mortality. Bacteremic infection with Rothia dentocariosa in immunocompetent persons is uncommon. Pacemaker lead-related endocarditis caused by Rothia spp. is rare and management guidelines are not defined. Case Presentation: We report a rare case of implantable cardiac defibrillator (ICD) lead endocarditis in an immunocompetent patient that was caused by Rothia dentocariosa. Conclusions: Clinicians should be aware of this rare cause of CIED lead infections and should be acquainted with the optimal strategies of prompt antibiotic therapy and removal of the infected device/leads.
TakoTsubo Syndrome: First an Acute Coronary Vasculitis and Then Prolonged Myocarditis?
Authors: Girolamo Olivia C , Surikow Sven Y , Ong Gao-Jing , Nguyen Thanh Ha , Kucia Angela M , Chirkov Yuliy Y , Horowitz John D
Published: April 2022

Since its initial description by Japanese investigators 30 years ago, TakoTsubo Syndrome (TTS) has variously been regarded as a form of acute coronary syndrome and also as a form of cardiomyopathy (or more accurately, a myocarditis). There is actually good evidence that TTS embodies both of these concepts, and the main purpose of this review is to present data that they occur sequentially. The initial phase of the disorder (over perhaps the first 48 hours post onset of symptoms) represents a form of vasculitis, with associated damage to the endothelial glycocalyx and associated permeabilization of blood vessels. This is followed by a more prolonged phase of myocardial inflammation and oedema, associated with inflammatory activation and energetic impairment within the entire myocardium. Although this phase subsides after several months, it may be followed by longstanding impairment of myocardial function, reflecting residual fibrosis. Understanding of this gradual transition in TTS pathogenesis from vasculature towards myocardium remains an important limitation of patient management, especially as many patients are still told that their hearts have “recovered” within 1–2 weeks. A number of important uncertainties remain. These include development of specific early and ongoing therapeutic strategies to be used to match the sequential pathogenesis of TTS. “And so these men of Indostan Disputed loud and long, Each in his own opinion Exceeding stiff and strong, Though each was partly in the right, And all were in the wrong!” From: Six wise men of Hindustan
Association between Physical Activity and the Risk of Mortality and Hospitalization in Older Korean Adults with Heart Failure
Authors: Yu Ga-In , Yang Pil-Sung , Kim Moon-Hyun , Jin Moo-Nyun , Jang Eunsun , Yu Hee Tae , Kim Tae-Hoon , Pak Hui-Nam , Lee Moon-Hyoung , Joung Boyoung
Published: April 2022

Background: Regular exercise improves the functional ability and quality of life of patients with heart failure (HF). However, studies on the results of intensity of exercise in the older population are scarce, especially in the Asian population. Method and Results: A total of 8982 older people (age ≥65 years) with HF were selected from the Korean National Health Insurance Service-Senior database (2005–2012). Participants were stratified according to the levels of physical activity per week as follows: (1) inactive group; (2) insufficiently active group: 1–499 metabolic equivalent task minutes (MET-min)/week; (3) active group: 500–999 MET-min/week; and (4) highly active group: ≥1000 MET-min/week. During a median follow-up period of 3.2 years, the incidence and risk of mortality were reduced in the insufficiently active (6.7 vs. 4.2 per 100 person-years, adjusted hazard ratio [HR], 0.82; 95% confidence interval [CI], 0.71–0.94; p < 0.001), active (3.8 per 100 person-years; HR, 0.81; 95% CI, 0.70–0.95; p = 0.010), and highly active (2.4 per 100 person-years; HR, 0.52; 95% CI, 0.41–0.67; p < 0.001) groups compared to inactive patients. Conclusions: In older Asians with HF, increased physical activity reduced the risk of all-cause mortality. The mortality-reducing benefit started at a lower physical activity compared to the World Health Organization guideline (500–999 MET-min/week), and the risk decreased with more physical activity.
Coronary Physiology: Delivering Precision Medicine?
Authors: Maitre-Ballesteros Laura , Riou Laurent , Marliere Stephanie , Canu Marjorie , Vautrin Estelle , Piliero Nicola , Ormezzano Oliviez , Bouvaist Helene , Broisat Alexis , Ghezzi Catherine , Fagret Daniel , Vanzetto Gérald , Djaïleb Loïc , Barone-Rochette Gilles
Published: April 2022

Coronary physiological assessment is now widely used to assess epicardial coronary lesions in cath lab. Based on clinical evidence, fractional flow reserve (FFR) is the gold standard method to select whether epicardial coronary lesions need revascularization. While additional epicardial indexes, such as instantaneous wave-free ratio (iFR), are also used for revascularization decision-making, several indexes are now also available to explore the coronary microcirculation. Therefore, coronary physiological assessment now allows to explore the entire coronary tree and offer the potential of precision medicine for patients affected by coronary artery disease (CAD). This paper will provide review of the epicardial and microvascular indexes available for the assessment of coronary physiology. More specifically, the already demonstrated contributions of these indexes in the management of CAD and the role they could play in precision medicine will be reviewed with special emphasis on chronic coronary syndrome.
A Brief History of Cardiomyoplasty: Worth Another Look?
Authors: Elefteriades John A.
Published: April 2022

This article reviews the concept and extensive experimentation done over two decades ago to convert and apply skeletal muscle for cardiac assistance—so called “cardiomyoplasty”. Skeletal muscle was either wrapped around a failing heart or fashioned into accessory cardiac pumping chambers. Although the era of cardiomyoplasty came to an end when the cardiac wraps were found ineffective, the concept of independent accessory skeletal muscle ventricles may be worth another look.
Change of Fibroblast Growth Factor 21 Level Correlates with the Severity of Diabetic Sensory Polyneuropathy after Six-Week Physical Activity
Authors: Molnár Ágnes , Szentpéteri Anita , Lőrincz Hajnalka , Seres Ildikó , Harangi Mariann , Balogh Zoltán , Kempler Péter , Paragh György , Sztanek Ferenc
Published: April 2022

Background: Diabetic neuropathy (DN) is a very frequent microvascular complication of type 2 diabetes mellitus (T2DM). Obesity and physical inactivity are well-known risk factors for T2DM. Fibroblast growth factor 21 (FGF21) is a liver-secreted hormone with several beneficial effects on obesity-related metabolic disorders. We aimed to investigate the effect of short-term physical activity on the levels of FGF21, and its correlation with the severity of peripheral sensory polyneuropathy in T2DM patients. Methods: Thirty patients with DN were enrolled in the study, compared to age- and gender-matched controls. We conducted a six-week aerobic training program, which meant treadmill and cycle ergometers three times a week. Anthropometric and laboratory parameters were measured for each patient before and after intervention. Serum levels of FGF21, TNF-alpha, irisin, leptin and adiponectin were measured by ELISA. The sensory perception threshold (CPT) was quantitatively measured using Neurometer®. Results: We found significant decreases in BMI, waist circumference, HbA1c and TNF-alpha levels. From baseline to six-week follow-up, FGF21 levels were significantly increased in DN patients. Significant negative correlations were shown between the changes in FGF21 levels and BMI, between changes in FGF21 and the improvement of CPT values, and between the changes in FGF21 and TNF-alpha levels. There was no difference in irisin, adiponectin and leptin levels in DN patients after aerobic training program. Conclusions: The physical activity may increase the level of FGF21 in T2DM patients with neuropathy. Our results highlight the importance of regular physical activity in the treatment of diabetic neuropathy.
Hypoxic Therapy as a New Therapeutic Modality for Cardiovascular Benefit: A Mini Review
Authors: Park Hun-Young , Kim Sung-Woo , Jung Won-Sang , Kim Jisu , Lim Kiwon
Published: April 2022

Cardiovascular diseases (CVDs) are recognized as one of the major causes of morbidity and mortality worldwide. Generally, most CVDs can be prevented by addressing behavioral risk factors, including smoking, unhealthy diet and obesity, lack of physical activity, and alcohol abuse. Therefore, it is important to have a healthy lifestyle by performing regular physical activity to improve cardiovascular health and diseases. However, a majority of adults worldwide do not meet the minimum recommendations for regular aerobic exercise, and overweight and obesity ratio continues to rise. In addition, obese individuals, with a high prevalence of CVDs, have a lower participation rate for exercise because of the strain on the musculoskeletal system. Hypoxic therapy, including exposure or exercise intervention under hypoxia, has been utilized as a new therapeutic modality for cardiovascular benefit and amelioration of CVDs. Hypoxic therapy shows various physiological and pathophysiological properties, including increased appetite suppression and dietary intake reduction, increased energy consumption, improved glycogen storage, enhanced fatty acid oxidation, improved myocardial angiogenesis or ventricular remodeling, augmentation of blood flow within the skeletal muscle vascular beds, and reduction of the burden on the musculoskeletal system making it applicable to patients with CVDs and obesity with attenuated cardiovascular function. In particular, hypoxic therapy is very effective in improving cardiovascular benefits and preventing CVDs by enhancing arterial function, vascular endothelial function, and hemorheological properties. These observations indicate that hypoxic therapy may be an important and essential strategy for improving cardiovascular health and reducing cardiovascular morbidity and mortality.
The rise of guesthouse tourism in the Greater Caucasus and the effects of the covid pandemic. The example of Lagodekhi town and its Protected Area, Georgia
Authors: Schmid Leonie Greta , Gugushvili Temur , Kohler Thomas
Published: April 2022

In Georgia, tourism has become a key sector of the economy, especially since the country opened up for private investment after independence in 1991. Guesthouses, the focus of this paper, present a typical example of such private investment. In dealing with this sector, we adopt a synoptic view, and look into development over time, services offered, motives for hosting guests, outcomes, and the effects of the COVID pandemic. Geographically, our focus is on the town of Lagodekhi and its Protected Area (PA) on the foot slope of the Greater Caucasus. Our methods included a review of literature, followed by a questionnaire survey in 2018 among all 23 guesthouses in the town, covering qualitative as well as quantitative aspects of the sector. To follow up on the effects of the pandemic, which reached the area in 2020, we did a re-survey among all houses in June 2021. The results show that all guesthouses are owner-occupied and family-run, with women taking the lead, following traditional gendered labour division. The owners see themselves as paid service providers but also as hosts, who offer insights into local culture free of charge based on traditional hospitality. We posit that this dual role is a unique selling proposition, distinguishing the sector from mass tourism, and presenting an ideal complement to the nature-based attractions of the PA. The COVID pandemic led to an almost total collapse of this sector, especially relating to foreign guests, by far the most numerous visitor group. But the guesthouses remain positive about the future and continue to invest in their houses. To conclude our paper, we present ideas relating to the future of guesthouse tourism in the study area, based on experience before and with the pandemic.
Japanese experience of using video games with a historical plot as tools of memory politics
Authors: Belov Sergey
Published: April 2022

The presented research is devoted to the study of the Japanese experience in the implementation of memory policy tasks through video games. The methodology of the work is built through a combination of comparative and structural analysis. The author concludes that video games can effectively popularize basic symbols related to key events in national history, while increasing the motivation of some gamers to in-depth study of the memorial narrative.
Resume Analisis Kurva Kepuasan Sama
Authors: Najjar Nadilah Anisah
Published: April 2022

Kurva kepuasan sama (indifference curve) adalah kurva yang menghubungkan titik-titik kombinasi dari konsumsi (atau pembelian) barang-barang yang menghasilkan tingkat kepuasan yang sama. Kurva kepuasan sama memperlihatkan semua kombinasi dari pilihan konsumen yang memberikan tingkat kepuasan atau utility yang sama bagi seseorang atau konsumen.
SISTEM INFORMASI MANAJEMEN PEMBUATAN PERANGKAT LUNAK "APLIKASI PENJUALAN TOKO DELIMA FLORIST BERBASIS ONLINE"
Authors: husna Mawaddatul
Published: April 2022

TUGAS PROPOSAL MAWADDATUL HUSNA SUFIUL. B. MATONDANG SISTEM INFORMASI 4
Marhaban Ya Ramadan
Authors: Sofanudin Aji
Published: April 2022

Mayoritas masyarakat Jawa menyambut dengan gembira hadirnya bulan suci Ramadlan dengan berbagai ekspresi. Sewaktu kecil, ayah saya selalu mengajak anak-anaknya potong rambut jelang puasa. Tempo dulu, banyak tetangga yang bersih-bersih rumah secara menyeluruh, bahkan “mewajibkan” rumahnya dilabur (dicat baru).
The Role of the Environment in Indonesian Language Learning
Authors: Harefa Destin Talenta
Published: April 2022

The environment will determine the quality of a person's language. In learning Indonesian, teachers can take advantage of the environment in developing teaching materials. In addition, the environment can act as an inspiration to build linguistic intelligence. In learning Indonesian, environmental conservation efforts can be applied in learning Indonesian through reading texts.
Investigation of Turkish Middle and High School Students’ Water Literacy as a Factor Predicting Targets for Sustainable Development Goals
Authors: Kucuk Arzu
Published: April 2022

This research was carried out to reveal the factors affecting the water literacy of middle and high school students in Turkey. In the study, in which a total of 155 children living in Rize of Turkey participated, the data were collected using the "Water Literacy Scale" developed by Sozcu and Turker (2020a). This measurement tool was implemented as online questionnaire. The scale consisted of three sub-dimensions, namely water saving, water consciousness, and water sensitivity, and a total of thirty items. Data analysis was performed in the SPSS program, using unrelated t and One-Way Anova tests. It was concluded that the water literacy of the children differed according to finding the news about the water crisis realistic, and having a concrete experience in reusing water in some dimensions. There was no difference between the water literacy of middle and high school students. Critical suggestions based on informal learning, including parents, were made to provide water literacy to children.
FILOSOFIS ILMU EKONOMI ISLAM
Authors: Annisa Nurul , Arkam Fadel , Astuti Sri , Aryam
Published: April 2022

Proses pembentukan teori ekonomi syariah berbeda dengan proses pembentukan teori yang ada pada umumnya digunakan dalam ilmu-ilmu sosial. para peneliti ilmu sosial, seperti halnya peneliti ilmu kealaman, seperti berusaha mencapai sesuatu yang belum diketahuinya berdasarkan premis-premis yang telah diketahui. sementara itu , doktrin islam dalam bidang ekonomi mengintervensi semua proses pembentukan teorinya.Ontologi ekonomi Islam dan menjadi karaketeristikanya ialah pandangan baru terhadap problematika dan fenomena realitas ekonomi seperti definisi sumber permasalahan ekonomi yang mengarah pada “maqashid syariah” dan juga tujuan ekonomi menuju “Falah”.Epistemologi dapat diketahui bahwa ilmu ekonomi diperoleh melalui pengamatan terhadap gejala sosial masyarakat dalam memenuhi kebutuhan hidupnya.Aksiologi dalam ekonomi Islam adalah nilai dan moral agama menjadi dasar dalam memberikan maslahat kepada umat manusia.
Sejarah Perbankan Syariah
Authors: Ramadhona Indah , amelia wanda , NOER MUH. AFTA , Bagaskara Eghytya
Published: April 2022

Perbankan syariah atau perbankan Islam (al-Mashrafiyahal-Islamiyah) adalah suatu sistem perbankan yang pelaksanaannya berdasarkan hukum Islam (syariah). Pembentukan sistem ini berdasarkan adanya larangan dalam agama Islam untuk meminjamkan atau memungut pinjaman dengan mengenakan bunga pinjaman (riba), serta larangan untuk berinvestasi pada usaha-usaha berkategori terlarang (haram). Sistem perbankan konvensional tidak dapat menjamin absennya hal-hal tersebut dalam investasinya, misalnya dalam usaha yang berkaitan dengan produksi makanan atau minuman haram, usaha media atau hiburan yang tidak Islami, dan lain-lain.
Metric Flow and bound Bousso
Authors: Vit Ku
Published: April 2022

Metric Flow and bound Bousso
Relative minus and absolute minus for science
Authors: Nonomura Yuusuke
Published: April 2022

There are no people who go to greengrocer to buy the minus one apple. There is also no person who sells the -1 m square land (+1m2). In the macro world, the general common sense (GCS) does not have an absolute minus object (AMO). Therefore, the GCS does not multiply minus the number. The GCS has relative minus (RM) but no absolute minus (AM).However, expert common sense (ECS) ordinarily performs the AM calculation. Concretely, ECS uses AMO, minus time and minus space. Therefore, limits, various mistakes, and problems in science are generated, such as directional problems, singularities, nonsmoothness (Millennium Prize problem), nonsolution differential equations (e.g., prey-predator equations: antigen-antibody equations) and quantum arguments. They have an adverse influence (negative impact) on children’s education. Do you still teach the AM in macro to children?However, the problems are solved by the RM (Str-operator), Zai-operator (existence), and Kyoku-operator (the differential value without an infinitesimal real number). They are primitive operators. And,UZai, which subtracts observation (View operator) from the Str-Zai operator (composition operator), generates the dynamics of elementary particles (primitive coordinate system), the imaginary number and Euler’s formula and identity, which are part of MpFtE from UZai, and hidden variables (ZaiFt function).
PROPOSAL PROYEK SISTEM INFORMASI MANAJEMEN PERUSAHAAN E-COMMERCE
Authors: SI4 M. Andika Rizky
Published: April 2022

Menjelaskan bagaimana membangun dan menjalankan sistem aplikasi
Peran Lingkungan dalam Pembelajaran Bahasa Indonesia
Authors: Harefa Destin Talenta
Published: April 2022

Lingkungan memiliki peran dalam pembelajaran bahasa Indonesia. Lingkungan akan menentukan kualitas kebahasaan seseorang. Dalam pembelajaran bahasa Indonesia, guru dapat memanfaatkan lingkungan dalam mengembangkan materi pembelajaran. Disamping itu, lingkungan dapat berperan sebagai inspirasi untuk membangun kecerdasan kebahasaan. Dalam pembelajaran bahasa Indonesia upaya pelestarian lingkungan dapat diterapkan dalam pembelajaran bahasa Indonesia melalui teks-teks bacaan
Student-Student Interaction in Online Learning During the Covid-19 Pandemic: A Case Study
Authors: Amrullah  , Sahuddin  , Nurtaat Lalu , Sribagus  , Fadjri Muhammad , Nanzah Zahratun
Published: April 2022

Despite numerous studies investigating various aspect of online learning amidst the Covid-19 pandemic, the empirical findings reporting about student(s)-student(s) interaction in micro-level of language teaching learning process is inadequately documented. Thus, this current study was in attempt to address this void by exploring how the students interact in online learning, identify the perception of the student about student-student interaction in online learning for effectiveness in online learning English teaching process. Framed in a case study, 5 students of a public University in West Nusa Tenggara participating in Teaching English for Young Learner (TEYL) course were purposefully recruited to participate in this study. The data were garnered from a series of semi-structured interviews and a 4-month virtual classroom observation and were analyzed using thematic analysis. The finding elucidates that students enjoyed their online learning interactions and they perceived that their language skills and knowledge increased significantly. The teacher was seen to have pivotal role in facilitating students to have effective interactions by providing various activities, prepared materials, and support. Practically, this study proposes some suggestions for teachers and students on how to establish effective student-student interaction in a language online classroom.
Expectations for Rhythmic Sounds Increase Bottom-Up Visual Attention
Authors: Motz Benjamin , Kruschke John K. , Hetrick William P. , James Thomas , Puce Aina
Published: April 2022

Similar to how attention can enhance or suppress a visual target in a specific location in space, attention can also tune the perception of a visual event at a specific moment in time. One way to observe this temporal tuning is to present an auditory stimulus aligned with a visual target event. In general, past research reported that a co-occurring auditory stimulus decreases the amplitude of the N1 component of the visual event-related potential (ERP), possibly suppressing bottom-up attention evoked by a visual target. However, an independent line of research found that an expected auditory stimulus, such as one embedded in a rhythmic pattern, increases N1 amplitude to a coincident visual target event. Here, we present a novel preregistered demonstration of this dissociation using the flash-lag paradigm. Specifically, we observe opposite effects of rhythmic (expected) and non-rhythmic (unexpected) sounds on the visual ERP to a coincident flash. Results suggest that expectation for an upcoming sound reverses the sound’s typical suppression of bottom-up visual attention. We discuss these findings in the context of the multisensory tuning of attention.
Gardner’s Syndrome and Myxoma: A Rare Clinical Case with Very Early Onset
Authors: Arias Juan Pablo Rodríguez , Arias Juan Pablo Rodríguez , García Elena Gómez , Pampin Martinez Marta Maria , Cebrian Carretero Jose Luis
Published: April 2022

Background: Gardner’s syndrome (GS) is an autosomal dominant inherited disease that predisposes individuals to a high risk of developing colonic polyposis, colorectal cancers, and multiple maxillofacial hard and soft tissue tumors. Odontogenic myxoma (OM) is classified as a benign locally invasive tumor of the jaws. It is estimated as the third most frequent odontogenic tumor, between 2% and 5% of cases. In the present study, we report and discuss a case of odontogenic myxoma in a 13-month-old patient diagnosed with GS.
Case Presentation: A 13-month-old patient was referred to our department with a fast-growing tumor located in the left nasomaxillary region and a family history of GS. Computed tomography imaging of the face with contrast was performed, showing a well-defined, insufflating osteolytic lesion located in the left nasomaxillary region, extending up to the inferior orbital wall. The tumor was biopsied, and he was diagnosed with OM. Radical resection was performed and the anterior maxilla wall was reconstructed with PDS. Subsequently, germline mutation in APC gene was found in the patient. Follow up was carried out up to seven years after the intervention, an excellent cosmetic outcome and no signs of recurrence were observed in the area.
Conclusion: Oral and maxillofacial surgeons must be aware of the different lesions which may be associated with systemic syndromes. OM may be first manifestation related to early diagnosis of GS and, lastly, colon cancer. OM could be an indication of referring to genetic counselling to determine the presence of the mutation in patients with or without familiar history.
Pemanfaatan Laman BIPA Daring dalam Konteks Multimodalitas bagi Pemelajar BIPA
Authors: Ramadloni Syukron
Published: April 2022

The learning process with web media is closely related to the use of multimodality in learning because students use various modes at the same time. BIPA Online as a reference for BIPA activities has never been studied in a scientific study. The purpose of this study is to describe how the use of multimodality on the BIPA Online is used in BIPA learning process. The technique of collecting data is through direct observation of the BIPA Online manager. In addition, semiotic analysis was used when watching and the technique used was the note-taking technique. The research method applied is qualitative with descriptive analysis. The research findings revealed that the BIPA Online is rich in material with multimodality in its presentation. The teaching materials discussed on this web cionsist of five types of semiotic systems. The study of multimodality texts is one of the studies in semiotics.