bluuebunny/crossref_metadata_2025 huggingface dataset:
Expert views on screening for tuberculosis infection in patients commencing treatment with a biologic agent
Authors: Sultana1,2 Adiba , Battista Migliori3 Giovanni , D’Ambrosio,4 Lia , García-García5 José-María , Rossato Silva6 Denise , Adrian Rendon5 Luis , R Codecasa7 Luigi , Blanc8 Francois-Xavier , Tiberi9 Simon , W M Ong10,11,12 Catherine , Heffernan13 Courtney , Sotgiu14 Giovanni , Centis3 Rosella , Caroline Dobler1,2 Claudia , Network The Global Tuberculosis
Published: September 2024

Objective: Many biologic agents cause some degree of immunosuppression, which can increase the risk of reactivation of tuberculosis infection (TBI). This risk is variable between individual biologics. We aimed to assess current (and recommended) clinical practice of TBI screening and treatment among patients initiating treatment with biologic agents. Methods: An online questionnaire was distributed via email to members of the Global Tuberculosis Network and associated professional organisations to seek insights into the screening for and treatment of TBI in patients treated with biologics. Results: A total of 163 respondents in 27 countries answered at least one question. For all biologics described in the questionnaire, respondents advised increasing screening relative to current practice. Observed and supported TBI screening rates in patients treated with TNF-a inhibitors were high, especially for older TNF-a inhibitors. Most participants supported TBI screening in patients treated with B- or T-cell inhibitors but not in those treated with interleukin inhibitors. Guideline awareness was higher for TNF-a inhibitors than for other biologic classes (79% vs. 34%). Conclusions: Although respondents stated that TBI screening rates are lower than what they consider ideal, there was a tendency to recommend TBI screening in patients treated with biologics not known to be associated with an increased risk of TBI. As a result, there is a potential risk of over-screening and over-treatment of TBI, potentially causing harm, in patients treated with biologics other than TNF-a inhibitors. There is a need to research the risk of TBI associated with biologics and for guidelines to address the spectrum of TBI risk across all types of biologics.
Primary prevention of venous thromboembolic complications in spinal cord injury: modern concepts
Authors: Belova Anna N. , Rakhmanova Evgenia  M. , Semenova Tatiana N.
Published: September 2024

Venous thromboembolism is a common complication following spinal cord injury that can significantly aggravate a pre-existing condition and lead to a death. Patients who suffer acute spinal cord injury have a higher prevalence of venous thromboembolism than patients who suffer other traumatic injuries with sparing of the spinal cord. It is important for physical medicine and rehabilitation specialists to have knowledge аbout primary prevention of venous thromboembolism in patients with acute, subacute and chronic spinal cord injury.
This article provides a brief overview of typical venous thromboembolism frequency (leg deep vein thrombosis and pulmonary embolism), pathogenesis peculiarities, venous thromboembolism risk factors and diagnostic considerations. The main attention is given to the primary thromboprophylaxis (methods and duration) depending on the spinal cord injury period and the spinal cord injury level. Further studies are required to clarify the optimal prophylaxis methods and protocols to prevent venous thromboembolism following spinal cord injury.
Impact of chronic kidney disease on the course and outcome of COVID-19
Authors: Sarana Andrey M. , Shcherbak Sergey G. , Vologzhanin Dmitry A. , Golota Aleksandr S. , Kamilova Tatyana A. , Kadin Sergey V.
Published: September 2024

COVID-19 is primarily a respiratory disease. However, patients with COVID-19 are at high risk for acute kidney injury or exacerbation of preexisting kidney disease, especially those with comorbidities such as hypertension, coronary artery disease, chronic liver disease, chronic kidney disease, and malignancies. We reviewed studies that assessed the association between chronic kidney disease and SARS-CoV-2 coronavirus infection and infection outcomes, including hospitalization, severe COVID-19, need for intensive care, COVID-19 progression, and death. The studies showed varied and often contradictory results, as the baseline data differ in many parameters, such as the period of the pandemic, quality and size of the sample, and degree of comorbidity. Nevertheless, the studies consistently revealed that chronic kidney disease is an unfavorable factor with regard to SARS-CoV-2 infection. Furthermore, concomitant chronic kidney disease predisposes patients with COVID-19 to severe COVID-19, viral pneumonia, development of acute respiratory distress syndrome, acute kidney injury, and other complications, which in turn are negative prognostic factors for mortality. Patients with chronic kidney disease who survived COVID-19 are more likely to develop post-COVID syndromes with various persistent or recurrent symptoms than convalescents without renal comorbidity. These patients require long-term monitoring and optimization of therapy and are priority for vaccination.
Health-Related Quality-of-Life Utility Values in Adults With Late-Onset Pompe Disease: Analyses of EQ-5D Data From the PROPEL Clinical Trial
Authors: Griffiths Alison , Shohet Simon , Johnson Neil , MacCulloch Alasdair
Published: September 2024

Background: Pompe disease is a rare lysosomal storage disorder, leading to accumulation of glycogen characterized by muscle weakness, fatigue, pain, and, in the longer term, a requirement for ventilatory and ambulatory support, and early mortality if untreated. Clinical evidence suggests that enzyme replacement therapy improves health outcomes for adults with late-onset Pompe disease (LOPD). PROPEL was a Phase 3, double-blind, randomized controlled trial, which evaluated cipaglucosidase alfa plus miglustat, vs alglucosidase alfa plus placebo in 123 adult patients with LOPD (clinicaltrials.gov: NCT03729362).

Objectives: To analyze EQ-5D health-related quality of life (HRQoL) utility data from PROPEL.

Methods: Multilevel modeling techniques (mixed regression methods) were used to analyze PROPEL EQ-5D-3L estimates and predict utility values for 7 health states previously identified in an economic evaluation for LOPD. In PROPEL, EQ-5D-5L values were assessed at screening and at weeks 12, 26, 38, and 52. EQ-5D-5L utility values were mapped to EQ-5D-3L values using the van Hout algorithm as recommended by the EuroQoL and the National Institute of Health and Care Excellence position statement at time of analysis. UK population tariffs were applied for all EQ-5D utility valuations. Utility values were predicted according to 6-minute walk distance (6MWD) and percent predicted sitting forced vital capacity.

Results: The mixed model predicted that EQ-5D-3L utility values for patients who could walk >75 m with LOPD ranged between 0.55 and 0.67 according to patient 6MWD and respiratory function. In this analysis, patients with a 6MWD ≤75 m, consistent with a health state requiring wheelchair support in the economic analysis, had a predicted utility value of 0.49. There were few patients in PROPEL who could walk ≤75 m at any time point in the study, hence, these utility estimates should be interpreted with caution. EQ-5D-3L utility estimates from PROPEL were consistent with previously reported EQ-5D-3L values in LOPD.

Conclusions: Overall, the results from our analysis indicate that important HRQoL losses are associated with reductions in mobility and respiratory function for patients with Pompe disease. The study provides important evidence of HRQoL utility values for patients with advanced LOPD, a population for whom published data are limited.
Arte gestacional como estratégia de humanização em uma Casa da Gestante, Bebê e Puérpera em Belém-Pa
Authors: Amaral Tillmann Ingrid Inez , Figueiredo de Montalvão Leite Luana Gabriela , Gomes Rocha Rony , Araújo Lobato Marinara de Nazaré , Monteiro Viana Gisele , Pinheiro das Chagas Francielma , Nazareno de Quadros Miranda Milton , Silva da Costa Leonardo , Figueiredo de Montalvão França Ana Paula , Lins da Silva Jéssica Maria
Published: September 2024

Este artigo tem por objetivo relatar a atividade realizada com um grupo de gestantes internadas em uma Casa da Gestante, Bebê e Puérpera de uma maternidade de referência no atendimento a gestações de alto risco, levando em consideração o que preconiza a Rede Cegonha e a Política de Humanização do Pré-natal e Parto. A ação ocorreu com a pintura da barriga de gestantes. A atividade teve o objetivo fomentar o bem estar em relação ao momento de incertezas vivido pelas participantes. A atividade foi organizada partindo de um plano de ações com uso da metodologia 5W2H, utilizada como ferramenta para o planejamento das ações, pautados na resposta às seguintes perguntas: “o que?”, “por que?”, “quem?”, “quando?”, “como?” e “quanto?”. Os achados no estudo evidenciaram que a pintura gestacional de mulheres internadas representa uma boa estratégia de humanização e também de relaxamento para as grávidas, haja vista o bem estar que proporciona, além de influenciar diretamente nas crenças e esperanças futuras relativas ao manejo da gestação.
Importância Da Mamografia Como Mecanismo Rastreador Precoce Do Câncer De Mama Em Pacientes Com Histórico Familiar: Uma Revisão
Authors: Nantes Fontoura Teofilo Rhuan , Dossena Carolina , Rodrigues Pereira da Silva Camilla , Dacas Dacheux Maria Júlia , Nichio Biazi Bruna Vitória , Rodrigues Frabetti Lanna Gabriela , Locatelli Stunitz Yuri , Azeredo de Andrade Daga Milena , Rodrigues de Freitas Lucas Mateus , Casagrande Maria Carolina , Satim Letícia
Published: September 2024

Introdução: O carcinoma mamário é uma das neoplasias mais prevalentes entre as mulheres em todo o mundo. Suas manifestações clínicas podem variar desde nódulos ou massas palpáveis até alterações na pele da mama, como retração ou mudança na cor do mamilo. Nesse contexto, a mamografia é considerada o exame padrão-ouro para o diagnóstico precoce de neoplasias, proporcionando um tratamento mais eficaz com menor risco para o paciente. Objetivo: Esta revisão tem como objetivo apresentar e discutir, de maneira concisa, os achados mais recentes e relevantes sobre o impacto da mamografia como um mecanismo de triagem precoce do câncer de mama em pacientes com histórico familiar. Métodos: As buscas foram realizadas nas bases de dados PubMed e Lilacs utilizando descritores de inclusão e exclusão selecionados. Cada artigo selecionado foi lido na íntegra por pelo menos dois pesquisadores. Resultados: Com base na seleção crítica da pesquisa, 14 artigos foram selecionados para esta revisão. Dados de 428.560 mulheres indicaram que as taxas de detecção de câncer foram menores em mulheres com menos de 40 anos de idade. Entrevistas com médicos revelaram que a avaliação de risco é influenciada por conhecimentos, crenças e experiências anteriores, criando barreiras para encaminhamentos apropriados para aconselhamento genético e programas de triagem. Conclusão: Em resumo, a mamografia desempenha um papel crucial na detecção precoce do câncer de mama, especialmente em mulheres na faixa dos 40 anos. Nesse contexto, mulheres com histórico hereditário de câncer de mama e/ou alterações nos genes BRCA1, BRCA2 e CHEK2 devem realizar mamografias com mais frequência, idealmente uma vez por ano. No entanto, são necessários mais estudos para determinar com precisão um plano terapêutico eficaz.
STUDY OF SCAVENGER BIRDS IN SOME REGION OF BUNDELKHAND TO ASSESS THE PROMISING BREEDING SITES FOR THEIR BREEDING CONSERVATION
Authors: Rajesh Sahu
Published: September 2024

Due to the fact that they consume carrion, vultures serve an important ecological purpose in addition to being very reliable indicators of the ecosystem's overall health. They are the only group of vertebrates that have been documented as being obligate scavengers. There are nine distinct species of old world vultures found in India. The Red-headed Vulture (RHV) is a species of vulture found in the United States that reaches a height of 2,000 meters throughout the nation. The inquiry was conducted in Madhya Pradesh, popularly known as Bundelkhand, and Uttar Pradesh, two states in India. The research zone was partitioned into grids with random location selection, each grid consisting of 15 square kilometers by 15 square kilometers. Within each of the selected grids, transects with a length of ten kilometers were successfully completed. In light of this, the quantities of vultures that were recorded over the years 2021 through 2023 were 46, 54, and 74, respectively. The population of RHV showed a continuous growth during the duration of the study that was observed, which indicates that the species is moving in a positive direction. In addition to the hurdles that are faced by other species of vultures, RHV is also face with considerable obstacles. Some examples of biotic and abiotic threats include habitat loss, predation, hunting, and disturbance; scarcity of food and water; changes in agricultural practices and land use; poisoning; and death from traffic accidents at feeding locations. The population trend is showing signs that are positive; but, in order to preserve the species, it will be required to simply maintain constant monitoring and put conservation measures into effect.
Best Practices for Integrating OAuth in Mobile Applications for Secure Authentication
Authors: Jaswanth Alahari  , Dasaiah Pakanati  , Harshita Cherukuri  , Om Goel  , Prof.(Dr.) Arpit Jain
Published: September 2024

For safe authentication in mobile apps, OAuth is becoming the de facto standard. Strong and reliable authentication methods are more important than ever before due to the meteoric surge in mobile app use. This need is satisfied by OAuth, which allows for protected resource access while protecting user credentials from prying eyes in third-party apps. In order to guarantee security and a smooth user experience, this abstract details best practices for incorporating OAuth into mobile applications, with an emphasis on critical concerns and tactics.
An overview of OAuth's fundamental concepts, such as its authorisation processes, token management, and scope definitions, is provided at the outset of the talk. Use cases include mobile apps that make use of the Authorisation Code Flow with Proof Key for Code Exchange (PKCE) highlight the need of selecting the appropriate OAuth flow. Here is some practical advice on how to put these ideas into practice: make sure the OAuth client is securely registered with the authorisation server, use the device's secure storage facilities to store tokens, and use the right techniques for token expiry and renewal.
A REVIEW ARTICLE ON AETIOPATHOLOGICAL STUDY OF KATIGRAHA (LOW BACK ACHE)
Authors: Dr. Dillip Kumar Hembram  , Prof. Dr. Sarita Mohanta  , Dr. Bhagya Ranjan Dash  , Dr. Biswajit Dash
Published: September 2024

Among all age categories, lower back ache is the most prevalent issue in the modern world. It bears similarities to the Ayurvedic condition katigraha. People in the modern world are tired of this situation. It is a condition where pain (Shoola) and stiffness (Stabhdhata) affect the low back (katipradesha). Katigraha is explained by Shodhala in the Kayachikitsa Khanda, Vataroga Adhikara. In this condition either Shuddha (pure) vata or samavata gets lodged at katipradesha or produces symptoms there. According to modern research, lower back pain is a chronic illness marked by an ongoing, pain, dull or severe pain in the lower back. It is a condition that affects a wide range of demographic groups and has numerous potential causes. In our ancient texts katishoola and katistabhdhata have been described in various clinical conditions. This article mainly emphasis on describing the katigraha condition more widely. This will help us to do treatment more efficiently.
KEYWODS: Katigraha, Low Back Ache
METHODS, TECHNOLOGIES AND TOOLS FOR INTELLIGENT INFORMATION PROCESSING ON THE DYNAMICS OF MIGRATION IN THE TULA REGION
Authors:   Doctor of Economics, Candidate of Physical and Mathematical Sciences, Associate Professor, Professor of the Department of Mathematics and Computer Science, Financial University under the Government of the Russian Federation (Tula Branch), Tula, Russia, Zhukov Roman A. , Prokopchina Svetlana V. ,   Doctor of Technical Sciences, Professor, Professor of the Department of «System Analysis in Economics», Financial University under the Government of the Russian Federation (Tula Branch), Tula, Russia, Kozlova Nadezhda O. ,   Candidate of Technical Sciences, Associate Professor, Financial University under the Government of the Russian Federation (Tula Branch), Tula, Russia, Plinskaya Maria A. ,   Student, direction «Business Strategy and Finance», Financial University under the Government of the Russian Federation (Tula Branch), Tula, Russia, Zhelunitsina Maria A. ,   Student, direction «Business Strategy and Finance», Financial University under the Government of the Russian Federation (Tula Branch), Tula, Russia, Koroleva Margarita A. ,   Student, direction «Business Strategy and Finance», Financial University under the Government of the Russian Federation (Tula Branch), Tula, Russia
Published: September 2024

The purpose of the study is to assess and analyze the dynamics of the number of arrivals and departures from the Tula region to calculate the migration increase (decrease) of the population based on a fuzzy model built within the framework of the Bayesian intelligent measurement methodology.
USING A FUZZY PROBABILITY APPROACH IN MODELING BIOLOGICAL POPULATIONS
Authors:   Doctor of Technical Sciences, Associate Professor, St. Petersburg Institute of Informatics and Automation of the Russian Academy of Sciences, St. Petersburg, Russia, Spesivtsev Alexander V. , Mikhailov Vladimir V. ,   Doctor of Technical Sciences, Professor, St. Petersburg Institute of Informatics and Automation of the Russian Academy of Sciences, St. Petersburg, Russia, Spesivtsev Vasiliy A. ,   Junior Researcher, Northwestern Center for Interdisciplinary Research on Food Security Problems – a separate structural unit of St. Petersburg FITZ RAS, St. Petersburg, Russia
Published: September 2024

Deterministic methods of building mathematical models of biological populations are being replaced by new ones based on the fuzzypossibility approach (FPA) using expert knowledge and their professional experience. The advantage of FPA is that the expert acts as an «intellectual informationdiagnostic system» with the content of all necessary information when solving a particular problem. This allows to reduce the time of model creation by orders of magnitude and does not require, as in deterministic approaches, their subsequent intellectualization, since the FPA uses directly the information from the expert. The article presents a synthesized mathematical model in a fivedimensional factor space of fuzzy linguistic variables, systematically describing a hardtoformalize phenomenon – change in the number of wild reindeer. The factor space was composed of fuzzy linguistic variables X1 – tension of food relations, qualitative variable; X2 – food competition with domestic reindeer, qualitative variable; X3 – natural mortality (mortality coefficient from 0,04 to 0,12; X4 – climatic impacts (annual trend of air temperature); X5 – anthropogenic impacts, qualitative variable. Y – population growth rate, as a percentage of the previous year's population (from –10 to 10%). The necessity of the conducted research is caused by the fact that since the beginning of the XXI century, there is a decrease in the number of deer to 700–750 thousand by 2009, to 417 thousand by 2017 and to 241 thousand in 2021. The catastrophic decline in the number of wild reindeer is a global trend. However, there is no consensus on the causes of such degradation. The created model quantitatively confirmed all five stages in the global development of the Taymir population for the last period from the 50s of the previous century to the present. It is suggested that the approach proposed in the article may be useful in identifying the causes of degradation of wild reindeer populations and developing measures to stabilize and restore the numbers of these animals.
THE MECHANISM OF AGRIBUSINESS PROCESSES TRANSFORMATION IN CONTEXT OF FOOD POTENTIAL SOVEREIGNIZATION
Authors:   Saratov State University of Genetics, Biology and Engineering named after N. I. Vavilov, Saratov, Russia, Sannikova Marina O. , Kuvshinova Ekaterina A. ,   VNIPIgazdobycha, Saratov, Russia
Published: September 2024

In the current difficult business conditions in the Russian Federation, due to the restrictive measures of unfriendly countries towards the Russian economy, there is a growing need for mechanisms to effectively increase the resilience of agricultural systems to sanctions risks, trade barriers and other external threats, reinforced by the low sovereignty of the country’s food potential. In this context, significant adaptive potential is concentrated in the transformation of business processes of economic entities that are producers of agricultural products and food, taking into account constantly changing business conditions. In this regard, the issues related to the development of a mechanism for the transformation of business processes seem relevant. The purpose of the study is to develop recommendations on the formation of the structure of the mechanism for the transformation of business processes in the agro-industrial complex in the context of the sovereignization of Russia’s food potential. The following tasks are to be solved: to assess current trends in the changing environment of food producers in Russia, in particular as a result of the establishment of barriers to Russian business; to identify key areas for ensuring the sustainable functioning of economic entities in conditions of turbulence and exogenous risks; to develop a generalized structure of the mechanism of transformation of business processes of manufacturers of agricultural products. The authors propose the structure of a distributed mechanism, represented by a risk warning system on the external contour of an economic entity that poses a threat to business process disruption; a system for responding to threats of technological process disruption, providing rapid restructuring of the entire chain of business processes; a reflection system responsible for a posteriori analysis of the operation of warning and response systems. The proposed structure of the mechanism for transforming the business processes of the agro-industrial complex can form the basis for further developments on the formation of such a mechanism and its practical use in order to adapt food producers to sanctions pressure, ensure the sustainability of production, and increase the country’s food security.
CRITERIA FOR THE EFFECTIVENESS OF MANAGING AN INVESTMENT PORTFOLIO OF FINANCIAL ASSETS IN THE PRACTICE OF A CONSTRUCTION ORGANIZATION
Authors:   St. Petersburg University of Management Technologies and Economics, St. Petersburg, Russia, Abbasov Elfak U.-O.
Published: September 2024

The purpose of the article is to analyze the key criteria that are used in the assessment of the investment portfolio of financial assets in the practice of construction organizations. The author systematized and investigated the conclusions of the authors’ scientific papers, which reveals that the definition of the main performance criteria should be used in the process of managing an investment portfolio of financial assets. For this reason, issues related to the optimization of the investment portfolio remain unresolved in the practice of construction organizations. The relevance of the study requires identifying key indicators that can be used by construction companies to solve the tasks that are set when deciding on the allocation of free financial resources and funds for their investment in specific securities and financial assets. The conditions that contribute to a higher efficiency of managing the investment portfolio of financial assets of the organization, taking into account the specifics of the activities of construction companies, are determined. In addition, the scientific article contains different approaches to criteria and indicators, with the help of which it is possible to more accurately determine how appropriate it is to manage an organization’s investment portfolio.
ON THE USE OF ARTIFICIAL INTELLIGENCE IN EDUCATION
Authors:   Moscow Institute of Physics and Technology (National Research University), Dolgoprudny, Moscow Region, Russia, Lanchakov Aleksandr B. , Filin Sergei A. ,   Plekhanov Russian Economic University, Moscow, Russia, Yakushev Aleksei Zh. ,   Plekhanov Russian Economic University, Moscow, Russia, Shtol Angel G. ,   Plekhanov Russian Economic University, Moscow, Russia
Published: September 2024

The purpose of the article is to analyze the practice of using artificial intelligence (AI) in education in Russia in the context of the digital economy. In the process of writing the article, methods were used: description, synthesis, analysis. The possible positive and negative consequences of the use of AI in the educational process, the forecast directions of training IT specialists and specialists who will have to work with AI in the process of their professional activities are analyzed. The novelty of the article is the proposal of a network or ecosystem type of training organization based on artificial intelligence. Recommendations on the practice of using artificial intelligence in education in Russia in the digital economy have been proposed.
Artificial Intelligence and Machine Learning as Business Tools: A Framework for Diagnosing Value Destruction Potential
Authors: - Md Nadil Khan , - Tanvirahmedshuvo , - Md Risalat Hossain Ontor , - Nahid Khan , - Ashequr Rahman
Published: September 2024

The use of intelligence (AI) and machine learning (ML), in business operations is becoming more common offering efficiency, decision making and innovation. However, there are risks of losing value if these technologies are not implemented and managed properly. This document suggests a way to identify the potential for value loss in AI and ML projects within companies. By considering factors, like data quality, model reliability, ethics and organizational readiness the framework helps evaluate the risk of losing value. By using this approach organizations can. Reduce the risks associated with AI and ML projects to ensure they contribute positively to business goals. The goal of this document is to help businesses understand how AI and ML projects can create or destroy value so they can make decisions while minimizing risks.
Bladder Wall Plexiform Neurofibromatosis in A Patient with NF1: Case Report and Literature Review
Authors: - DR.NAHID NIAJ , - DR.PINTU BISWAS
Published: September 2024

While von Recklinghausen provided a detailed description of the clinical entity of neurofibromatosis and is credited with its discovery, Smith initially described the condition in 1849. With an estimated frequency of one in every 3000 live births, it is a hereditary dysgenesis transmitted as a Mendelian dominant trait. It is a main neural crest derivation condition that also affects the nerve sheath's fibroblasts, Schwann cells, and supportive mesenchymal elements.
Tirunelveli Experience of Wide-Awake Local Anesthesia No Tourniquet (WALANT) Hand Surgery
Authors: - S Venkatesh Babu , - Akshay Kumar SV
Published: September 2024

We are presenting our experience with12 Hand Surgical Patients treated with the WALANT principle (Wide-awake Local Anesthesia No Tourniquet) and validate the benefits of this brilliant technique during the COVID Pandemic in a less resourced region of India.

These Hand Challenges were mainly Trauma, which was successfully treated by the Senior author using the WALANT standard. The results had revealed big satisfaction in all the patients and happiness to the surgeons.
Quality of Life in Patients Living with Andro-gentic Alopecia: A Cross Sectional Observational Study
Authors: - Abhay Paul Baghwar , - Arun Chandran Ramachandran
Published: September 2024

Alopecia is a chronic dermatological disorder in which people lose some or all of the hair on their head and sometimes on their body as well. It is a chronic inflammatory disease that affects the hair follicles. It is neither life threatening nor painful, though there can be irritation of the skin, as well as physical problems resulting from the loss of eyelashes and eyebrows.This study aim to improve the quality of life and prescription pattern in androgenic alopecia. The goal of the study was to assess the quality of life of subjects living androgenic alopecia and to assess the prescription pattern of subjects with androgenic alopecia.This was a cross sectional observational study. The study was conducted Outpatient department of Dermatology in ESI MC PGIMSR, Rajajinagar. All the subjects (n=36) meeting the inclusion and exclusion criteria were briefed about the purpose of the study and the informed consent was obtained. The subject’s demographic details and responses were collected with the help of a standardized questionnaire. The collected data were entered in Microsoft Excel and appropriate descriptive analysis was performed. It was observed that a majority of the subjects were prescribed with minoxidil 5% (58.33%). On comparing the QOL scores, in each domain it was found that emotion has the highest average while the function has lowest average. scores in subjects of different age groups, it was found that the subjects belonging to the age groups 26-35 groups had high average scores (32.84%) and 36-45 groups had low average scores (28.96%).From this study, we got to know that the quality of life of male gender is affected more rather than female. Minoxidil 5% was most commonly prescribed drug and overall dosage form prescribed were topical agent.
Exchange rate flexibilization and macroeconomic determinants: Evidence from MENA region
Authors: - MOUTAIB Nouhaila , - LAHRICHI Younès
Published: September 2024

Many emerging economies have significantly changed their economic policies by adopting floating exchange rate regimes. This article aims to investigate the relationship between exchange rate variations and key macroeconomic indicators in the MENA region, focusing specifically on Egypt, Tunisia, and Turkey. The study employs regression analysis to explore how macroeconomic factors such as inflation, interest rates, trade balances, foreign exchange reserves, etc. influence exchange rate movements in these economies. By conducting a comprehensive regression model, we aim to provide insights into the complex dynamics of exchange rate fluctuations and their implications for economic stability and policymaking in the MENA region.
Health And Menstrual Hygiene Of Adolescent Girls In Vijayapura District.
Authors: - Shilpa. Manohar. Meeshi , - Prof. Vijaya. B. Korishetti
Published: September 2024

One-fifth of the world's population is in their adolescent years, and in India, 20.9% of people are in this age range. Adolescent girls were unable to obtain the proper knowledge due to social prohibitions and cultural beliefs, which resulted in poor hygiene habits. Due to these behavior's, microorganisms are harbored, which raises the risk of Genito-urinary diseases. To better understand the menstrual hygiene practices of teenage girls in the Vijayapura district, a study on the subject was undertaken. The study's goal was to investigate the menstrual hygiene habits of teenage females in Vijayapura. The study's secondary data-based paper's methodology. As a result of this study, teenage girls' health instruction must focus on menstrual hygiene and health for them to continue practicing good hygiene. With increased understanding and safe menstrual practices, reproductive system infections and their consequences can be prevented.
New Records of Soil Galumnid Mites (Acarina: Cryptostigmata) from Dampa Tiger Reserve, Mizoram, India
Authors: - Shampa Sarkar
Published: September 2024

Among all the soil micro- arthropods, mites are predominant and playing important role in increasing soil fertility through organic decomposition and they are inhabiting in all types of soil but predominantly found in soil litter, humus, and compost heaps. The present research work has been done to identify and prepare a record of the soil Galumnid mites from this region as very few works has been done on the taxonomy of this important group in this geographical area as well as in India. Only one major work has been found which was published by Sanyal (2009)[1] on the study of oribatid mites of Mizoram. Amongst all the States of India, Mizoram has the highest area under forest cover in terms of percentage of geographical area. Dampa Tiger Reserve of western Mizoram of India is located at Indo-Myanmar hotspot in the Lushai hills is one of the remotes Tiger Reserve of the country and immensely rich in floral and faunal biodiversity.
9 species including 5 genera of Galumnid mites are newly recorded for the first time from this area of study.
Corporate Social Responsibility, Ethical Leadership, Organizational Climate and Employer-Employee Relations in a Trading Company
Authors: - Julie Ann Gallego
Published: September 2024

Workers are essential for organizational vitality, playing a crucial role in sustainable expansion. This study, anchored in social exchange theory, investigates corporate social responsibility, ethical leadership, organizational climate, and employer-employee relations in a Trading Company. Using quantitative, descriptive, comparative, and correlational design with a sample size of 162 out of 279 employees, the study reveals significant correlations among key factors. Despite the company's excellence, the researcher suggests there's room for enhancement.
Formation and Evolution of Special Stellar Types: A Comprehensive Study of Special Stars.
Authors: - Anupam Das , - Baibhab Ghosh
Published: September 2024

This article presents a comprehensive study of the formation, evolution, and distinctive characteristics of special stellar types, including protostars, super-giants, pulsars, red giants, etc. By exploring the life cycles of these stars, we gain a deeper understanding of the nuclear reactions, gravitational influences, and electromagnetic spectra that govern their development and eventual demise. Through a synthesis of observational data, theoretical models, and recent advancements in astrophysics, this research aims to elucidate the intricate processes driving the life cycles of these stellar phenomena. The findings contribute to the broader knowledge of stellar dynamics, offering insights into the mechanisms of stellar evolution and the fundamental forces shaping our universe.
Rural Community Engagement In Higher Education Institutions – Revisiting the Existing Literature
Authors: - Shivani Mishra , - Kera Ram
Published: September 2024

In India, Social work education has been mainly Western-centric and failed to address societal needs and their problems. There is a growing realization of limitations of the Western model in the Indian context that calls for Indigenous social work practice. It is because of the borrowed teaching content from Western literature, and there is hardly any relevance in the Indian context.
We are living in the era of global research and innovation, where one could not underestimate scale and important of the HIEs. To achieve goals of socio-economic development, HIEs can contribute effectively, through community engagement program. In 2018, UGC launched an ambitious Quality Mandate that emphasis to improve the societal linkages of HEIs which could be pivotal for students to become socially productive. In addition, there is constant need in the Higher Institute to develop better understanding and incorporating the issues which are very happening in the society and it could be achievable by bring in social responsibility and community in their vision and mission itself, in result of this definitely there will be improvements in the standard of research as well teaching.
This paper center on works on indigenous knowledge reflects how the criteria for involvement to rural community could be pivotal within the local context by exploring vivid literature on indigenization and their influence on the paradigm of social work and its curriculum specially which is related to rural community engagement in Higher Education Institution.
Fundamentals of Emergency Initial Assessment: A Comprehensive Review
Authors:   AL Zahrani Fahad Ali Ahmed, AL Khaldi Mohammed Khalid Hamoud, AL Mutairi Abdulaziz Ruzayq Bati, AL Anazi Abdullah Mohammed Turki, AL Mutairi Nawaf Saqer, AL Rehaili Abdulaziz Ajal and AL Motairi Ebtesam Mansour
Published: September 2024

Emergency initial assessment is a critical process in emergency medicine, ensuring that patients receive timely and appropriate care based on the severity of their condition. This comprehensive review explores the fundamental principles of emergency initial assessments, focusing on the primary and secondary survey methods, including the ABCDE approach (Airway, Breathing, Circulation, Disability, Exposure). The review also discusses the essential tools and techniques used during assessments, such as vital signs monitoring, diagnostic tools, and triage systems. Best practices and guidelines from leading medical organizations are highlighted, alongside evidence-based approaches that improve patient outcomes. Additionally, the review addresses common challenges faced during emergency assessments, such as time constraints, resource limitations, and communication barriers. By emphasizing the importance of continuous training, technological advancements, and quality improvement initiatives, this review aims to provide healthcare professionals with a solid foundation for performing effective emergency initial assessments. The article concludes by identifying areas for future research and potential innovations that could further enhance emergency care practices.
Kebijakan Pencegahan Kemiskinan Sebagai Respon Kenaikan Harga Beras di Kabupaten Tulungagung
Authors: Sujoko Arif
Published: September 2024

Harga beras medium sudah melewati harga eceran tertinggi (HET), bahkan per 16 November 2023, harganya sudah 20% di atas HET. Kenaikan harga beras tersebut berdampak secara langsung dan cepat pada daya beli penduduk miskin dan rentan. Akibatnya, penduduk miskin sulit keluar dari kemiskinan. Bahkan, kemiskinan berisiko meningkat karena penurunan konsumsi penduduk rentan. Untuk menurunkan harga beras, telah dilakukan operasi pasar. Akan tetapi, bukti menunjukkan bahwa operasi pasar tersebut tidak efektif. Oleh karena itu, butuh pendekatan lain yang bisa membantu masyarakat, khususnya kelompok masyarakat miskin dan rentan. Dalam jangka pendek, pemerintah daerah bisa memberikan bantuan langsung tunai (BLT) responsif ketika harga beras medium sudah 10% di atas HET dan memperbaiki kualitas data terpadu kesejahteraan sosial sehingga bantuan pangan dari pemerintah pusat bisa tepat sasaran. Pendekatan lain untuk jangka menengah-panjang adalah meningkatkan produksi padi di Kabupaten Tulungagung, khususnya dengan menjamin ketersediaan air irigasi sepanjang tahun.
A IMPORTÂNCIA DA PSICOTERAPIA NOS TRANSTORNOS DE TDAH E AUTISMO
Authors: OLIVEIRA DA SILVA PAULA NATALIA MOSCONI , Florêncio Fernandes Moret Marcia Cristina
Published: September 2024

O TDAH é um transtorno caracterizado por sintomas deletérios de desatenção, agitação psicomotora e impulsividade, inapropriados para os níveis de desenvolvimento e que levam ao comprometimento do desempenho dos afetados, enquanto o transtorno do espectro autista (TEA) um transtorno do neurodesenvolvimento de início precoce, caracterizado por comprometimento persistente da comunicação/interação social recíproca e padrões restritos e repetitivos de comportamento, interesses ou atividades. Partindo desse princípio, a psicoterapia visa fornecer treinamento cognitivo para habilidades prejudicadas e problemas de mudança de comportamento, além de ter como objetivo o melhoramento do desempenho acadêmico, das relações psicomotoras e ainda para melhoramento da fala. Destaca-se que a avaliação neuropsicológica possibilita abranger os aspectos cognitivos, emocionais e comportamentais do indivíduo, possibilitando assim, contribuir ao desenvolver a orientação a pais e professores, em relação aos modelos, formas e esquemas cerebrais envolvidos e as diversas possibilidades e variabilidade de estratégias pedagógicas possíveis e necessárias a serem aplicadas. Os resultados das avaliações neuropsicológicas podem ser utilizados para subsidiar o desenho de estratégias de intervenção, como a reabilitação neuropsicológica. Este visa trabalhar aspectos cognitivos, comportamentais e emocionais para melhorar a funcionalidade e a qualidade de vida de crianças e adolescentes.
ADHD is a disorder characterized by deleterious symptoms of inattention, psychomotor agitation, and impulsivity, inappropriate for the levels of development and that lead to the impairment of the performance of those affected. In contrast, autism spectrum disorder (ASD) is an early-onset neurodevelopmental disorder characterized by persistent impairment of reciprocal social communication/interaction and restricted, repetitive patterns of behavior, interests, or activities. Based on this principle, psychotherapy aims to provide cognitive training for impaired skills and behavior change problems and improve academic performance, psychomotor relationships, and speech enhancement. It is noteworthy that neuropsychological assessment makes it possible to encompass the cognitive, emotional, and behavioral aspects of the individual, thus making it possible to contribute to the development of guidance to parents and teachers concerning the models, forms, and brain schemes involved and the various possibilities and variability of possible and necessary pedagogical strategies to be applied. The results of neuropsychological evaluations can be used to support the design of intervention strategies, such as neuropsychological rehabilitation. It aims to work on cognitive, behavioral, and emotional aspects to improve children and adolescents' functionality and quality of life.
Folic Acid Supplementation for Blood Pressure Reduction in Hypertension: A Meta-Analysis
Authors: Harqiqi Andreafika Kusumaningtyas , Eva Supriadi
Published: September 2024

Background: Hypertension is a major risk factor for cardiovascular disease. While antihypertensive medications are the cornerstone of treatment, adjunctive therapies like folic acid supplementation have gained attention for their potential to lower blood pressure. This meta-analysis aims to comprehensively assess the impact of folic acid supplementation on blood pressure in hypertensive individuals.
Methods: A systematic search of electronic databases (PubMed, Embase, Cochrane Library) was conducted from January 2018 to December 2023 to identify randomized controlled trials (RCTs) evaluating the effect of folic acid supplementation on blood pressure in adults with hypertension. Data on systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP) were extracted. A random-effects model was used to pool data, and heterogeneity was assessed using the I² statistic.
Results: Twenty-three RCTs involving 2,853 hypertensive participants were included. Folic acid supplementation was associated with a significant reduction in SBP (mean difference [MD] -2.93 mmHg, 95% confidence interval [CI] -4.11 to -1.75, p < 0.00001), DBP (MD -1.87 mmHg, 95% CI -2.63 to -1.11, p < 0.00001), and MAP (MD -2.21 mmHg, 95% CI -3.01 to -1.41, p < 0.00001) compared to placebo or control. Subgroup analyses revealed that the blood pressure-lowering effect of folic acid was more pronounced in individuals with low baseline folate levels, those with higher baseline blood pressure, and in studies with longer durations of supplementation.
Conclusion: Folic acid supplementation appears to be a safe and effective adjunctive therapy for reducing blood pressure in hypertensive individuals. These findings support the potential role of folic acid in improving cardiovascular outcomes in this population.
Konseling Behavioral dengan Teknik Desensitisasi Sistematis Untuk Mereduksi Anxiety
Authors: Oktavia Anisa , Kasih Fitria , Usman Citra Imelda
Published: September 2024

Tujuan penelitian ini adalah untuk menguji efektifitas konseling behavioral dengan teknik desensitisasi sistematis untuk mereduksi anxiety pada peserta didik. Penelitian ini menggunakan metode kuantitatif eksperimen dengan desain penelitian One Grup Pretest and Postets, sedangkan teknik pengambilan sampelnya dilakukan dengan teknik total sampling. Instrumen yang digunakan yaitu angket, sedangkan untuk analisis data menggunakan interval persentase dan analisis uji t. Hasil dari penelitian ini adalah adanya penurunan perilaku anxiety peserta didik sesudah mengikuti layanan konseling behavioral dengan teknik desensitisasi sistematis. Terlihat bahwa rata-rata tingkat anxiety pada peserta didik sebelum diberikan layanan konseling behavioral dengan menggunakan teknik desensitiasi sistematis adalah 191.33 dengan rata-rata tingkat anxiety pada peserta didik sesudah diberikan layanan konseling behavioral dengan menggunakan teknik desensitiasi sistematis adalah 125.  Jadi dapat disimpulkan bahwa konseling behavioral dengan teknik desensitisasi sistematis behasil mereduksi anxiety pada peserta didik kelas X fase E11 di SMAN 1 Gunung Talang. Berdasarkan hasil penelitian yang telah peneliti lakukan bisa dikatakan berhasil, namun peneliti selanjutnya dapat melakukan perluasan sampel dan penggunaan teknik-teknik lain dalam mereduksi anxiety.
ДОСЛІДЖЕННЯ СТАНУ ПЕРЕКИСНОГО ОКИСЛЕННЯ ЛІПІДІВ У ДОРОСЛИХ ХВОРИХ НА ВІТРЯНУ ВІСПУ
Authors: Volobuieva Olha , Dorosh Diana , Pavlikova Ksenia , Sevastianova Tetiana , Grek Ivan , Kushnir Vasyl
Published: September 2024

Мета дослідження — оцінити в динаміці стан перекисного окислення ліпідів та антиоксидантної системи у дорослих хворих на вітряну віспу залежно від тяжкості захворювання. Матеріали та методи. В поточне дослідження було відібрано 240 хворих на вітряну віспу (142 жінки та 98 чоловіків) віком від 18 до 40 років. До контрольної групи увійшло 30 осіб. Вітряну віспу було діагностовано за допомогою клінічних, серологічних та молекулярно-генетичних методів. Оцінку стану перекисного окислення ліпідів у хворих на вітряну віспу ґрунтували на визначенні сироваткових дієнових кон’югатів, малонового діальдегіду та загальної окисної активності плазми крові. Результати. Це дослідження продемонструвало, що у дорослих хворих на вітряну віспу в гострому періоді захворювання посилюється процес перекисного окислення ліпідів і знижується активність антиоксидантної системи. Нами було встановлено, що у пацієнтів даної групи у міру погіршення клінічних проявів достовірно підвищується активність перекисного окислення ліпідів і знижується активність антиоксидантної системи, що відіграє важливу роль у розвитку цитолітичного синдрому. Висновки. Зниження активності антиоксидантних ферментів і порушення функціонування глутатіонової системи у хворих на вітряну віспу стають більш вираженими в міру зростання тяжкості захворювання. Внаслідок цього відбувається посилення вільнорадикальних ланцюгових реакцій і їх неконтрольоване зростання викликає незворотне пошкодження мембран різних клітин, що лежить в основі вісцеропатій у хворих на вітряну віспу.