bluuebunny/crossref_metadata_2025 huggingface dataset:
Nonlinear Evolutionary PDE-Based Refinement of Optical Flow
Authors: Doshi Hirak , Kiran Nori Uday
Published: May 2022

The goal of this paper is to propose two nonlinear variational models for obtaining a refined motion estimation from an image sequence. Both the proposed models can be considered as a part of a generalized framework for an accurate estimation of physics-based flow fields such as rotational and fluid flow. The first model is novel in the sense that it is divided into two phases: the first phase obtains a crude estimate of the optical flow and then the second phase refines this estimate using additional constraints. The correctness of this model is proved using an evolutionary PDE approach. The second model achieves the same refinement as the first model, but in a standard manner, using a single functional. A special feature of our models is that they permit us to provide efficient numerical implementations through the first-order primal-dual Chambolle-Pock scheme. Both the models are compared in the context of accurate estimation of angle by performing an anisotropic regularization of the divergence and curl of the flow respectively. We observe that, although both the models obtain the same level of accuracy, the two-phase model is more efficient. In fact, we empirically demonstrate that the single-phase and the two-phase models have convergence rates of order O(1/N2) and O(1/N) respectively.
MALDI-TOF MS profiling of piscine Acinetobacter species from wastewater-related waters
Authors: Topic-Popovic Natalija , Kazazic Snjezana , Coz-Rakovac Rozelindra
Published: May 2022

Acinetobacter species are common inhabitants of freshwater and marine ecosystems with a capacity to induce disease in affected fish. To facilitate their rapid and reliable identification, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), was applied to Acinetobacter from fish. The aims of the study were, thus, to identify and profile the Acinetobacter species from tissues of fish living in a vulnerable environment impacted by wastewaters, and to assess the potential of MALDI-TOF MS as a method for discriminating these acinetobacters. Fish were sampled from waterways impacted by the activity of a wastewater treatment plant. Samples of gills, spleen, kidney and liver were streaked onto general-purpose media to purity. The profiling and identification of acinetobacters was conducted with MALDI-TOF MS, with the samples prepared by ethanol/formic acid extraction.The identified acinetobacters were retrieved from gills (68.96 %), kidney (13.79 %), liver (10.34 %), and spleen (6.89 %). The Acinetobacter species isolated from all tested fish tissues were A. johnsonii (79.31 %), A. pittii (10.34 %), A. tandoii (3.44 %), A. guilouiae (3.44 %), and A. gerneri (3.44 %). Highly probable and probable species identifications were obtained for 48.27 % of all acinetobacters tested, indicating fully reliable identification. MALDI?TOF MS gave excellent identification and profiling results for piscine Acinetobacter species from the wastewater-affected waterways. It is a recommendable technique for future Acinetobacter species discrimination, as accurate and rapid identification of these bacteria is critical in both environmental pollution management and human/veterinary clinical diagnostics.
A Short Review on Reverse Osmosis Membranes: Fouling and Control
Authors: Maqbool Nida
Published: May 2022

Reverse Osmosis (RO) is the process of separating dissolved salts from water with the help of semipermeable membranes. Membrane based solution are now widely accepted technology to combat safe drinking water shortage. Reverse osmosis has increasing market shares due to reduced cost and improvements in the process. This paper reviews the major issue of fouling that is faced during operation of RO and ways to regulate them. Fouling is categorized into many classes and the control is discussed respectively. It also discusses basics of RO, modular arrangements for RO membranes as well as multiple options for pretreatment which is a mandatory requirement of the process. Final discussion is the ways to consider while disposing of brine.
mproving Gas Permeability Measurements for Environmental Monitoring and Management
Authors: P Tuccimei
Published: May 2022

Intrinsic permeability is a crucial parameter to interpret soil gas data recorded from monitoring stations in different environmental settings. It is also fundamental for environmental management and pollution reme diation. An improved version of a permeameter (PRM3) recently developed for environmental applications is presented and calibrated against a reference instrument (RADON - JOK produced by RADON v.o.s.). The innovations of this prototype are: i) the absence of the flow meter, and ii) a membrane pump in place of a rotary vane device. Proper calculation of the permeability from Darcy’s law is provided, as well as a modified formula for permeability determination in volcanic areas. Actually, soil gas viscosity and permeability are affected by changing gas temperature and composition. The effects of these two parameters on soil gas viscosity and permeability are also displayed. The second part of the paper shows the employ of permeability measurements in environment al monitoring. The aim of these field - works was the study of lateral and vertical variability of soil permeability at a very small scale (step of 0.25 m) and the effect of intrinsic permeability on gas transport through the soil and on gas concentration al ong depth profiles . We chose 2 different test sites: Valle della Caffarella (Roma, Italy) and Solfatara Volcano (Pozzuoli, Italy) areas. A specific protocol, designed to check any interference among permeability measurements carried out at very close dista nces demonstrated that no disturbance is occurring. Intrinsic permeability profiles resulted to be good proxy indicators for the degassing style of the two areas. In both cases, it gave important hints to interpret environmental data and help in the manage ment of the sites.
Advanced Techniques for Wastewater Treatment: A Review
Authors: S Yadav
Published: May 2022

Freshwater in lake and pond are often found to be polluted by heavy metals such as As, Zn, or Pb which are toxic in nature and non - biodegradable. Heavy metals are readily consumed by both aquatic flora and fauna present in the freshwater environment. It also polluted the air, water, and soil. Thus, they have adverse impact on the entire ecosystem. These heavy metals also enter the hum an systems through food consumed. This review discusses the methods and their mechanism used to reduce the amount of such heavy metals The methods which are in practice are Electrochemical Treatment (Electrocoagulation, Electro - Floatation, and Electro - Depo sition), Physicochemical Process (Chemical Precipitation, Ion - Exchange, and Adsorption), Membrane Filtration (Nanofiltration, Reverse Osmosis, Microfiltration, Ultrafiltration, and Electro - Dialysis),and Photo - Catalysis and Nanotechnology Treatment.
A Luxação do menisco externo – um caso clínico raro
Authors:   Rio Ave F C, Ribeiro Basil , Farinha Eduardo ,   Unidade de Saúde e Performance da Federação Portuguesa de Futebol, Lisboa, Nascimento Luís ,   Unidade de Saúde e Performance da Federação Portuguesa de Futebol, Lisboa, Noronha José Carlos ,   Unidade de Saúde e Performance da Federação Portuguesa de Futebol, Lisboa
Published: May 2022

In the postero-external angle of the knee there are many supportive structures important for knee stability. The pathology is complex, in diagnosis and treatment. Despite the athlete’s recurring complaints, physical examination and MRI may be normal and the diagnosis may be delayed. Dislocation of the external meniscus is difficult to diagnose, often taking time if there is no high level of suspicion and especially if there is no associated meniscal rupture. The treatment is surgical-arthroscopic and consists of suturing the poplitomenomeniscal fascicles and associated injuries. The return to sport takes a long time, never less than three months. The authors describe the clinical case that occurred in a professional beach soccer player.
Um atleta com pé pendente
Authors:   Serviço de Medicina Física e de Reabilitação, Centro Hospitalar Lisboa Ocidental, Lisboa., Moeda Frederico , Pinho Sérgio ,   Serviço de Medicina Física e de Reabilitação, Centro Hospitalar Lisboa Ocidental, Lisboa., Calado Duarte , Hatia Madjer , Tomás Nuno ,   Serviço de Medicina Física e de Reabilitação, Centro Hospitalar Lisboa Ocidental, Lisboa.
Published: May 2022

Foot drop is a pathology with a significant functional impact on athletes and can be caused by multiple etiologies, including common peroneal nerve palsy. As risk factors, we highlight the presence of polyneuropathies, recent weight loss and nerve compression. The prognosis of this injury depends essentially on the etiology and severity of the nerve injury, which can range from relatively benign to irreversible injuries. The authors describe a clinical case of an athlete with foot drop due to common peroneal nerve palsy who completed a rehabilitation program with complete resolution of this condition.
https://www.btpnadzor.ru/archive/protivopozharnaya-zashchita-mashinnykh-zalov-atomnykh-elektrostantsiy-s-ispolzovaniem-mnogofunktsionalnykh-robototekhnicheskikh-kompleksov
Authors:   «FR» Engineering Centre of Fire Robots Technology, LLC, Nemchinov S.G. , Harevskiy V.A. ,   «FR» Engineering Centre of Fire Robots Technology, LLC, Gorban Yu.I. ,   «FR» Engineering Centre of Fire Robots Technology, LLC, Tsarichenko S.G. ,   NRU MGSU
Published: May 2022

The problematic issues of the organization of fire extinguishing process in the engine rooms of nuclear power plants are considered. The need of prompt response to the occurrence of combustion source at the initial stage is substantiated. With the existing methods of ensuring fire safety, it is not always possible to achieve this goal. A conceptual approach is proposed concerning the construction of a system using robotic fire extinguishing installations, the hardware-software control complex of which allows to prevent the development of a fire. This is ensured by monitoring and analysis of the facility state, development of the control commands for the multifunctional fire protection complex. The innovative system for monitoring fire situation and fire extinguishing was created, which adapts in accordance with the dynamics of the development of a fire and a change in the situation. It is based on the software and digital solutions for ensuring comprehensive full-scale protection of the facilities from fires, accidents, and explosions. The risks to the life and health of the facility personnel and firefighters involved in extinguishing were minimized due to the absence of exposure to hazardous fire factors and their consequences. As a result, an unacceptable economic damage is prevented in case of fires and emergencies at the protected objects. Proposed complex with separate systems included in it differs from the traditional methods of fire protection. It is fully adapted to the likely scenarios for the development of the situation at the facility. As a result, the fire protection system is formed, which is based not on the general requirements (standards), but on the realistically possible emergency events. This approach not only ensures the efficiency of fire detection and elimination, but also reduces the cost of equipment operation.
To the Problem of Environmental Protection of the Russian Donbass
Authors:   North Caucasus State Technological University, Golik V.I. ,   Moscow Politechnic University
Published: May 2022

16 % of all the mineral resources in the world belongs to Russia, but currently its base is characterized by the depletion of rich and large mineral deposits. The relevance is increased concerning the search for and development of technologies that ensure a more complete and comprehensive use of the subsoil reserves. At the same time, one of the important criteria for the efficiency of mineral extraction technologies is the influence of the products of the activities of mining and processing enterprises on the state of the environmental ecosystems. The article substantiates the relevance of technologies development for a more complete use of the recoverable reserves. A criterion for the efficiency of the technologies for the extraction of mineral raw materials is proposed in the form of reducing the influence of the products of the mining and processing enterprises activities on the environment state. Aspects of metal extraction from tailings in a disintegrator mill are investigated. The forecast is provided related to the reduction of the threat to living matter due to the implementation of the concept of radical waste–free processing of low–quality mineral raw materials. Technologies with metal leaching and complete disposal of coal processing waste will become attractive from an economic point of view, when the modern methods of preparing mineral raw materials for use in industry give way to the environmental methods. The efficiency of the technology is evaluated based on the long–term statistical indicators. It is determined by the ratio of the compensation costs and damage from the waste storage, the production capacity of the recycling enterprise and its technological level. The concept of handling substandard mineral raw materials is based on the fact that if it is impossible to assess the actual damage to humans, flora and fauna, the possibility of causing this damage should be technologically excluded, i.e. not to preserve, but to dispose of the tailings.
Improvement of Safety and Efficiency of Cleaning Settled Dust in the Premises of Mining and Processing Enterprises
Authors:   Krivoy Rog National University, Gurin A.A. , Shapovalov V.A. ,   Krivoy Rog National University, Lapshin A.E. ,   Krivoy Rog National University, Lyashenko V.I. ,   GP «UkrNIPII promtekhnologii»
Published: May 2022

The results of study are given concerning the issues of improving safety and efficiency of cleaning settled dust in the premises of mining and processing enterprises using a mobile autonomous dust collection unit. The following is used in the work: data from literary sources and patent documentation in the field of technologies and technical means to improve safety and efficiency of cleaning settled dust in the premises of mining and processing enterprises; substantiation of the parameters of the operational characteristics of a mobile autonomous dust collecting plant; laboratory and production experiments; physical modeling. It is shown that when cleaning dust from the metal structures, equipment, as well as covering their surfaces, two nozzles were used: for cleaning caked dust and a flattened pipe with a diameter of 25 mm. Cleaning speed of 1 m2 of metal structures was 1.6–1.9 min. It was found that on the horizontal and lateral surfaces, as well as on the floor, a nozzle with a slit length of 240 mm and a width of 4.3 mm showed good results. Cleaning speed with such a nozzle is 1.33–1.48 m2/min. When the concrete floor is uneven or the thickness of the dust layer increased to 5–8 mm, the cleaning speed decreased to 0.55 m2/min. The design of the dust collecting plant and its operation modes are proposed, which allow collecting up to 0.6 t/h of the settled dust. Dust content in the air in the crushing shop of the sorting plant of the Rodina mine (Krivoy Rog, Ukraine) after cleaning the settled dust decreased from 4.5 to 2.5 mg/m3. Economic calculations showed that in addition to the social effect of using a dust collecting plant, an additional economic effect is possible, obtained by recovery and return of the collected dust to the technological process. The results of industrial tests confirmed its high efficiency. For the conditions of its work at the crushing and sorting factory of the Rodina mine, the expected economic effect is 5960 UAH per year.
Den Konsens vor der Krise schaffen! Weshalb Resilienz-Projekte oft auch Changeprojekte sind
Authors: Steeger Oliver
Published: May 2022

Pandemie, steigende Energiekosten, gerissene Lieferketten, drückender Fachkräftemangel: Immer häufiger gehen Unternehmen durch Krisen. Mit speziellen Resilienz-Projekten könnten sich viele Unternehmen besser auf solche Krisen vorbereiten. Die Idee: Unternehmen analysieren Risiken, wappnen sich mit Maßnahmen gegen mögliche Bedrohungen und erarbeiten Notfallpläne für den Fall des Falles. Indes, bei solchen Projekten handelt es sich in aller Regel um Changeprojekte. Im Ernstfall müssen die Mitarbeiter unverzüglich und entschlossen handeln. Changemanagement-Fachmann Winfried Berner erklärt im Interview, weshalb unternehmensweite Konsensprozesse wichtig sind, welche Rolle das Top-Management spielt – und welchen Preis man für Resilienz in Kauf nehmen muss.
Voraussetzungen für die agile Transformation. Ist die agile Projektmanagementmethode auch für Sie geeignet?
Authors: Fawaz Emadeldin , Krupke Chris
Published: May 2022

In Deutschland stehen das agile Projektmanagement und die agile Transformation vor finanziellen und kulturellen Herausforderungen. Auf die wichtigsten Herausforderungen wird eingegangen und sinnvolle Lösungs-Szenarien werden diskutiert. Die Softwareanbieter befinden sich in einer paradoxen Situation: Einerseits müssen sie ihren Kunden ein Höchstmaß an Flexibilität und Akzeptanz für ständige Veränderungen bieten, andererseits müssen sie das Budget und ihre Gewinn-Marge unter Kontrolle halten. Agile Projektmanagement-Methoden werden auf dem deutschen Markt als DIE „one-size-fits-all“-Lösung präsentiert. Diese falsche Annahme wird diskutiert und ein allgemeiner Überblick über die Voraussetzungen für eine agile Transformation gegeben.
Der Projektmanager als Handwerksmeister
Authors: Barth Martin , Sarstedt Margit
Published: May 2022

Hochwertige, akademische Projektmanagement-Ausbildung ist ein – gegenwärtig und zukünftig – bedeutsames Qualitätskriterium einer Hochschule. Die Unternehmen benötigen allerdings gerade im Projektmanagement keine „wohlgebildeten“ Theoretiker, sondern sich schnell zu „Handwerksmeistern des Projektmanagements“ entwickelnde Persönlichkeiten. Ausgehend von Erläuterungen zur „Unvollkommenheit“ der Praxis zeigen die Autoren auf, wie die Klippen beim „Praxistransfer“ umschifft, die Werkzeugkästen der Projektmanager entwickelt und die akademischen Lehrkonzepte zielführend ausgestaltet werden können.
Konservative Anarchisten
Authors: Köhler Jens
Published: May 2022

Die Kolumne „Ehrlich und Priesberg“ möchte mit unterhaltsamen Dialogen rund um das Thema „Mensch – Kommunikation, Verhalten, Entscheidungen“ Denkanstöße für den PM-Alltag geben.
Paradigm of international relations in the modern age (the concept of Paul Kennedy)
Authors: Sych Oleksandr
Published: May 2022

The article considers the concept of international relations proposed 30 years ago by the famous historian and political analyst Paul Kennedy. The purpose of the article. The author of the article tried to find out how relevant its key provisions are for understanding both the history and the current state of international relations. Methodology: retrospective analysis. Conclusions. P. Kennedy traced and explained how the various Great Powers have risen and fallen, relative to each other, over the five centuries since the formation of the „new monarchies‟ of Western Europe and the beginnings of the transoceanic, global system of states and to the end of the twentieth century. He analyzed in great detail the character and main tendencies of international relations for the last five centuries. Such analysis allowed him to identify the factors that determine the internal logic and content of international relations in the stated period, first of all the economic changes and military conflicts. According to P. Kennedy, the present large actors in the international system are thus compelled to grapple with the twin challenges which have confronted all their predecessors: first, with the uneven pattern of economic growth, which causes some of them to become wealthier (and, usually, stronger), relative to others; and second, with the competitive and occasionally dangerous scene abroad, which forces them to choose between a more immediate military security and a longer-term economic security. So, the concept of P. Kennedy helps not only to a deeper understanding of the historical process in the Modern Age, but also offers methodological tools based on historical analysis to predict – to a certain extent – the tendencies of future international development.
History of studying chronorithms in the regulation of physiological functions of the human organism
Authors: Тymofiychuk Inha , Semenenko Svitlana , Slobodyan Ksenia , Semenenko Vasyl
Published: May 2022

Materials and methods. Analysis of domestic and foreign literature, which highlights the physiological significance chronorhythms and problems of desynchrony and historical stages. Main part. The role of the pineal gland and epiphyseal hormone melatonin in diurnal and seasonal rhythms, sleepactivity to date is undeniable. In animals and human melatonin secretion pineal gland coincides with normal sleep clock. There is a hypothesis that melatonin plays an important role role in opening the so-called gates of sleep and in inhibiting modes activity. Melatonin secretion is subordinate circadian rhythm. The concentration of the hormone in the blood maximum in the dark, minimum - in the light. Synthesis and the activity of the hormone increases after sunset, and the peak concentration is observed around 3 o'clock at night. Conclusions. Analysis of changes in chronorhythms and their inconsistencies helps identify: 1. New approaches to diagnosis, prevention and improvement of temporary schemes of medical measures at diseases of various forms. 2. The impact of desynchrony on organs and body systems. 3. The role of mechanisms of adaptation of the organism to environment.
THE FEATURES OF THE COURSE OF SARS-COv-2 INFECTION IN THE SYSTEM "MOTHER-FETUS-NEWBORN": LITERATURE REVIEW
Authors: Znamenska T. , Vorobiova O. , Melnik O. , Marushko Y. , Samoylenko I.
Published: May 2022

Viral pandemic that had started in Uhan (Hubey provence, Korea) in 2019, resulted in identification of a new β-coronavirus type, capable of contaminating people, 2019-nCoV, later named SARS-CoV-2. There are 5 known highly contagious strains of the virus. SARS-CoV-2 causes a clinical syndrome called COVID-19 with a set of symptoms ranging from a light infection of the high respiratory tract up to a severe pneumonia with a high respiratory distress-syndrome and even fatal outcome. People of all age groups are likely to be infected and even newborns are not an exclusion. The lesion of this group of patients is of a particular interest among physicians of various specialties, including neonatologists. The article analyzes the latest data from foreign and domestic literature on the risks of infection, especially the course of infection in the system "mother-fetus-newborn", the neonatal period in children, and complications of COVID-19 infection in newborns.
Imam Ali Ibn Musa al-Ridha (A. S.)-The Exquisite Sun of Bani Hashim
Authors: Dr. Syeda Farhat Fatima
Published: May 2022

Ali Ibn Musa al-Rida was the eighth great grandson of Fatima Zehra (daughter of Prophet Mohammad, peace be upon him) and Ali Ibn Abi Talib and he is also the eighth Imam of Shiite believers.  He was an embodiment of etiquette, manners and charity and he imparted to us the qualities of a believer. His teachings were ‘How a man should strive to be a believer of Allah (S.w.t)?’He highlighted in his preaching’s the ways to seek the pleasure of Allah (s.w.t) was through piousness, tolerance and persistence in our righteous deeds.  He also emphasized us that for a believer to control his/her nafs (psyche)is prominent among his actions.  Because of Imam Ali Ridha’s (a. s.) high moral traits and pleasing personality, he (a. s.) was considered the exquisite sun of Bibi Fatima Zehra and the Bani Hashim clan.  This paper aims to show that Imam Ali Ibn Musa al-Ridha’s reward from Allah (s.w.t) is complete peace of mind as he stuck to his spiritual values being away from his homeland
Clinicopathologic findings and urolith composition for green iguanas (Iguana iguana) with urolithiasis: 21 cases and 132 stones (1996–2020)
Authors: Cerreta Anthony J. , Keller Krista A. , Gardhouse Sara M. , Lulich Jody P. , Guzman David Sanchez-Migallon
Published: May 2022

OBJECTIVE

To document the clinical signs, diagnosis, and treatment of urolithiasis in green iguanas (Iguana iguana) and to report on the composition of uroliths from green iguanas submitted to the Minnesota Urolith Center for analysis.

ANIMALS

21 green iguanas with urolithiasis.

PROCEDURES

Medical record databases of multiple veterinary teaching hospitals were searched from 1996 through 2020. Emails were sent to all facilities that submitted a urolith from a green iguana to the Minnesota Urolith Center from 1996 through 2020. Signalment; presenting complaint; physical examination findings; hematologic, biochemical, and diagnostic imaging findings; treatment; necropsy results; and survival times were described for each patient.

RESULTS

Iguanas most commonly presented with nonspecific clinical signs, but 9 of the 21 iguanas had clinical signs associated with the urogenital tract. Twelve iguanas had a palpable mass in the caudal coelom. All uroliths were visible on radiographs. Surgery was performed on 15 iguanas; 3 died secondary to intra- or postoperative complications. Iguanas that underwent surgery had a median survival time of 39 months. Necropsy was performed on 5 iguanas, and urolithiasis contributed to the decision to euthanize or was the cause of death for 4. Uroliths from 132 iguanas were analyzed, and all were composed of 100% uric acid salts.

CLINICAL RELEVANCE

Green iguanas with urolithiasis may not have clinical signs or physical examination findings associated with the urinary system, and hematologic and biochemical abnormalities are nonspecific. Green iguanas should be routinely examined for uroliths, and surgical treatment should be pursued.
Development of the Smart T-Shirt for Monitoring Thermal Status of Athletes
Authors: Stojanović Sandra , Geršak Jelka , Uran Suzana
Published: May 2022

Athletes are often subjected to a great physical strain during training and competition. Sport activities performed in hot and humid conditions may result in different heat illnesses with mild or fatal consequences. Against this background it is important to know the thermal state of athletes during physical activity.

This article presents the development of a smart T-shirt for monitoring the thermal status of an athlete. The smart T-shirt was created by embedding an electronic system with temperature and humidity sensors that allows the measurement of temperature and the relative humidity of the microclimate. A smart T-shirt is comfortable, and integrated sensors and electronics do not affect wearing comfort. A good concurrence between the temperature and humidity results from using the smart T-shirt, and thus the medical device was achieved. Data obtained can be of great importance to the sports staff who will be able to monitor the athletes' thermal state during matches and competitions.
No escape from COVID-19 consequences: cross-sectoral evaluation of impact on unemployment in Slovakia
Authors: Svabova Lucia , Tesarova Eva Nahalkova , Strakova Lenka , Durica Marek
Published: May 2022

The coronavirus disease 2019 (COVID-19) pandemic, which hit the world in 2020 and is still persisting, has significantly impacted many areas of people's lives. The shutdown anti-pandemic measures implemented by the governments also caused the development of unemployment worldwide. In Slovakia, the restrictions or even complete closure of the operation and activities of the companies caused rising unemployment in some sectors, while in some sectors, the impact was not so substantial. Therefore, the main aim of this study was to analyse and quantify the impact of COVID-19 pandemic on unemployment in various sectors of economic activities in Slovakia. For impact evaluation, a counterfactual approach was used, with analysis of time series development and statistically created counterfactual situation. The analysis was based on real data about the unemployment situation in Slovakia in the period January 2013–April 2021. The results of the study showed that the most affected sectors according to the NACE classification were F – construction, I – accommodation and food service activities and R – arts, entertainment and recreation, showing an increase in unemployment of 89%, 88%, and 65%, respectively. The analysis in this study showed that the impact of a pandemic should be quantified among the sectors, as there are large differences in unemployment caused by the pandemic. From these findings, it is necessary to deduce the different intensities and amount of state aid to companies or employees in these sectors. The results of the study should help to target the policy interventions better to mitigate the impact of the pandemic.
RAF-1 Mutation Associated with a Risk for Ventricular Arrhythmias in a Child with Noonan Syndrome and Cardiovascular Pathology
Authors: Făgărășan Amalia , Al Hussein Hamida , Ghiragosian Rusu Simina Elena
Published: May 2022

Introduction

Noonan syndrome (NS) is a dominant autosomal disease, caused by mutations in genes involved in cell differentiation, growth and senescence, one of them being RAF1 mutation. Congenital heart disease may influence the prognosis of the disease.

Case presentation

We report a case of an 18 month-old female patient who presented to our institute at the age of 2 months when she was diagnosed with obstructive hypertrophic cardiomyopathy, pulmonary infundibular and pulmonary valve stenosis, a small atrial septal defect and extrasystolic arrhythmia. She was born from healthy parents, a non-consanguineous marriage. Due to suggestive phenotype for NS molecular genetic testing for RASopathies was performed in a center abroad, establishing the presence of RAF-1 mutation. Following rapid progression of cardiac abnormalities, the surgical correction was performed at 14 months of age. In the early postoperative period, the patient developed episodes of sustained ventricular tachycardia with hemodynamic instability, for which associated treatment was instituted with successful conversion to sinus rhythm. At 3-month follow-up, the patient was hemodynamically stable in sinus rhythm.

Conclusions

The presented case report certifies the importance of recognizing the genetic mutation in patients with NS, which allows predicting the severity of cardiac abnormalities and therefore establishing a proper therapeutic management of these patients.
Renal Manifestations and their Association with Mortality and Length of Stay in COVID-19 Patients at a Safety-net Hospital
Authors: Gomez-Paz Sandra , Lam Eric , Gonzalez-Mosquera Luis , Cardenas-Maldonado Diana , Fogel Joshua , Gabrielle Kagan Ellen , Rubinstein Sofia
Published: May 2022

Background

Renal involvement in COVID-19 leads to severe disease and higher mortality. We study renal parameters in COVID-19 patients and their association with mortality and length of stay in hospital.

Methods

A retrospective study (n=340) of confirmed COVID-19 patients with renal involvement determined by the presence of acute kidney injury. Multivariate analyses of logistic regression for mortality and linear regression for length of stay (LOS) adjusted for relevant demographic, comorbidity, disease severity, and treatment covariates.

Results

Mortality was 54.4% and mean LOS was 12.9 days. For mortality, creatinine peak (OR:35.27, 95% CI:2.81, 442.06, p<0.01) and persistent renal involvement at discharge (OR:4.47, 95% CI:1.99,10.06, p<0.001) were each significantly associated with increased odds for mortality. Increased blood urea nitrogen peak (OR:0.98, 95%CI:0.97,0.996, p<0.05) was significantly associated with decreased odds for mortality. For LOS, increased blood urea nitrogen peak (B:0.001, SE:<0.001, p<0.01), renal replacement therapy (B:0.19, SE:0.06, p<0.01), and increased days to acute kidney injury (B:0.19, SE:0.05, p<0.001) were each significantly associated with increased length of stay.

Conclusion

Our study emphasizes the importance in identifying renal involvement parameters in COVID-19 patients. These parameters are associated with LOS and mortality, and may assist clinicians to prognosticate COVID-19 patients with renal involvement.
Zdalna edukacja i jej wpływ na szkolne osiągnięcia: badania przekrojowe w Polsce i na Ukrainie.
Authors: Długosz Piotr
Published: May 2022

Zdalna edukacja jest traktowana jako negatywne zjawisko prowadzące do powstania straty edukacyjnej, luki kompetencyjnej. W odpowiedzi na pojawienie się tego problemu zostały przeprowadzone pierwsze tego typu badania reprezentatywne podczas trwania zdalnej edukacji, które mają na celu pokazanie opinii uczniów na ten temat. W badaniu została wykorzystana metoda sondażu reprezentatywnego realizowanego techniką CAPI na próbie 1000 uczniów w Polsce i 1022 na Ukrainie. Wyniki badań pokazują, że według subiektywnej oceny uczniów poziom ich wiedzy szkolnej uległ obniżeniu w porównaniu do okresu sprzed pandemii. Analizy wykazały też, że głównym czynnikiem odpowiedzialnym za poczucie edukacyjnej straty jest wtórny efekt pandemii. Uczniowie, którzy mieli problemy społeczne w wyniku pandemii, u których pogorszyła się kondycja psychofizyczna, którzy mieli problemy poznawcze w czasie lekcji online najbardziej odczuli obniżenie się poziomu wiedzy szkolnej.
La entrevista periodística. Análisis discursivo e interaccional
Authors: Haverkate Henk
Published: May 2022

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Dystopian Futures: Ugandan Science Fiction and Post-Apocalypse Contagions
Authors: Nabutanyi Edgar Fred
Published: May 2022

Uganda, like most countries on the African continent, has in the recent past grappled with existential pandemics such as AIDS, Marburg disease, cholera, Ebola, and currently the Covid-19 pandemic. All the above-mentioned disease outbreaks have often unleashed unimaginable suffering on Uganda’s population. This is perhaps why Ugandan scholars and public intellectuals—especially its writers such as Mary Karooro Okurut, Moses Isegawa, Jennifer Nansubuga Makumbi, and Austin Ejeit—have used fiction to offer insights into the various contours of these contagions. For example, in their interrogation of one of the worst pandemics to hit the Ugandan society—AIDS—a host of writers have centred a cautionary tale motif and verisimilitude to show how behavioural change can effectively combat disease outbreaks. This article builds on this substantial Ugandan archive of plague writing by focusing on one genre of Ugandan writing—science fiction—that has not received much critical attention for its exploration of pandemics. I explore how Dilman Dila’s “A Leafy Man,” “Where Rivers Go to Die” and “The Taking of Oleng” use science fiction tropes to proffer insights in contemporary Ugandan plagues. I argue that Dila uses science fiction to effectively delineate the causes of, how to cope with and the myths that circulate about these catastrophic occurrences in the Ugandan public sphere. Opsomming Soos die meeste lande op die Afrika-vasteland het Uganda onlangs met eksistensiële pandemies soos vigs, Marburg, cholera en ebola geworstel, benewens die huidige Covid-19-pandemie. Al die bogenoemde siekte-uitbrekings het dikwels ondenkbare lyding vir Uganda se bevolking meegebring.  Dalk is dit die rede waarom Ugandese vakkundiges en openbare intellektuele—veral skrywers soos Mary Karooro Okurut, Moses Isegawa, Jennifer Nansubuga Makumbi, en Austin Ejeit—fiksie gebruik het om insig in die verskillende kontoere van hierdie besmettings te bied. Byvoorbeeld, in hul ondersoeke oor een van die ergste pandemies wat die Ugandese samelewing getref het, naamlik vigs, het vele skrywers ’n waarskuwende verhaalmotief en skynwaarheid die middelpunt gemaak om te wys hoe gedragsverandering die uitbreking van siektes doeltreffend kan bekamp. Hierdie artikel bou voort op dié omvattende Ugandese argief van skryfwerk oor siektes, deur te fokus op een genre van Ugandese skryfwerk—wetenskapsfiksie—wat nie veel kritiese aandag gekry het vir die bestudering van pandemies nie. Ek ondersoek hoe Dilman Dila se “A Leafy Man,” “Where Rivers Go to Die” en “The Taking of Oleng” wetenskapsfiksie-stylfigure gebruik om insig oor hedendaagse Ugandese plae te bied. Ek voer aan dat Dila wetenskapsfiksie gebruik om ’n doeltreffende beeld te skep van die oorsake van hierdie katastrofiese verskynsels wat in die Ugandese openbare sfeer sirkuleer, hoe om dit te hanteer en die mites daaromtrent.
Being Human in a Time of Catastrophe: African Feminism, Feminist Humaneness, and the Poetry of Joyce Ash
Authors: Nkealah Naomi
Published: May 2022

This article explores what it means to be human in a time of health catastrophe, and introduces the concept of feminist humaneness. Feminist humaneness is an offshoot of African feminism and is about women practicalising their feminism by expressing kindness, care, compassion, empathy and consideration for other women in times of sickness, disease, pandemics and other health catastrophes. The article establishes connections between being feminist and being humane using the poetry of Cameroonian writer Joyce Ash. Ash’s poetry constructs feminist humaneness as a socially responsive and practical feminism that fosters human relationships.
Opsomming
Hierdie artikel bestudeer wat menswees in ’n tyd van gesondheidskatastrofe behels, en stel die konsep van feministiese menslikheid bekend. Feministiese menslikheid is ’n vertakking van Afrika-feminisme en handel oor vroue se praktikalisering van hul feminisme deur welwillendheid, sorg, medelye, empatie en bedagsaamheid teenoor ander vroue in tye van siekte, pandemies, en ander gesondheidskatastrofes te toon. Die artikel gebruik die poësie van die Kameroense skrywer Joyce Ash deur ’n verband daar te stel tussen feministies wees en menslik wees. Ash se poësie konstrueer feministiese menslikheid as ’n maatskaplik responsiewe en praktiese feminisme wat menslike verhoudings koester.
Suplementação de ferro na população pediátrica: uma revisão integrativa
Authors: Do Bomfim Ana Beatriz Repinaldo Menezes , Reis Bruno Cezario Costa
Published: May 2022

Objetivo: Analisar o padrão das suplementações de ferro de acordo com a idade. Avaliando, assim, os principais benefícios adquiridos com essa medicação. Métodos: A abordagem metodológica deste estudo propõe uma compilação bibliográfica de pesquisa qualitativa de caráter descritivo a partir de uma revisão abrangente da literatura utilizando dados da National Library of Medicine, Biblioteca Virtual em Saúde e Directory of Open Access Journals. “Anemia Iron-Deficiency”, “Infant” e “Supplements” estavam entre os termos utilizados. Artigos de jornal, ensaio clínico, randomizados ou não randomizados, estudos de caso-controle, estudo coorte, acesso livre, publicado em inglês, português, espanhol, entre 2017 e 2022 e faixa etária até 23 meses foram os critérios de inclusão utilizados. Resultados: A ferro suplementar profilática é uma estratégia de previsão para as etapas onde a anemia ferropriva é considerada um problema grave de rigidez. Várias doses e estratégias periódicas foram utilizadas. Considerações Finais: Dessa forma, a suplementação com sulfato ferroso 25 mg/ml é a melhor escolha na prevenção e tratamento, uma vez que possui melhor resposta ao tratamento, adesão e poucos efeitos adversos.
Single Centre Experience: Bening and Malign Hematological Patients with COVID-19
Authors: TIĞLIOĞLU Pınar , ALBAYRAK Murat , AFACAN ÖZTÜRK Hacer Berna , TIĞLIOĞLU Mesut , SAĞLAM Buğra , REİS ARAS Merih , YILMAZ Fatma , MARAL Senem , MALKAN Ümit Yavuz
Published: May 2022

Introduction

Coronavirus disease 2019 (COVID-19) were declared as pandemic by World Health Organization. With this study, we aimed to define our patients who were followed up with malign or benign hematological diagnoses and diagnosed with COVID-19; determine the distribution of this infection in patient groups and contribute to the literature by creating descriptive statistics with its clinical and demographic features.

Patients and methods:

It is planned to retrospectively examine patients with a history of COVID-19 who were followed up in Hematology Department of Dışkapı Yıldırım Beyazıt Training and Research Hospital with benign and malignant diagnoses.

Results:

88 patients who had COVID-19 infection while being followed in our clinic due to hematological diseases were included in the study. 77 patients had been followed by hematologic malignancies and 11 patients had been followed by benign hematological disease.In the group with malignancy, COVID was found most frequently in patients diagnosed with Philadelphia chromosome negative myeloproliferative neoplasms (22%), nonhodgkin lymphoma (19%) and multiple myeloma (16%). ITP (64%) was the most common disease in patients with benign hematological disorder who had COVID history. 52 (67%) of the malignant cases and 8 (73%) of the bening cases were found to be followed up with the disease in remission.

The all patient's most common symptoms at COVID-19 diagnosis were fever (77%), cough (70%) and weakness (65%). 45% of the patients were isolated at home, 48% were required hospitalization. 49% of patients had mild; 27% had moderate and 24% had severe COVID-19 infection. Almost all of the patients in the moderate and severe disease group were followed up in patients diagnosed with malignant hematological disease. 16 (18%) patients received mechanical ventilation and 16 (18%) patients was transferred intensive care unit. All of the patients who were intubated and needed intensive care were diagnosed with malignant hematological disease. 17 patients died due to COVID-19 infection. The mortality rate was 22% in patients with diagnosis of malignant hematological diseases, and 19% when all patients (malignant and bening) were included.

Conclusion:

In conclusion, the COVID-19 pandemic is a problem all over the world. Determining the course of the disease in certain diagnostic groups is important in the management of both the main disease and the COVID-19 infection. Therefore, the contribution of such recording studies to the literature is important and valuable.
Pandemi Sürecinde Günübirlik Cerrahi Geçiren Hastaların Preoperatif Anksiyete Düzeyle-rinin Değerlendirilmesi
Authors: Vermişli Sevgi , Ulamış Bilgen , Çevik Esra
Published: May 2022

Giriş: Bulaşıcı hastalıklar insanlar için önemli bir endişe kaynağı olup COVID-19 pandemisi sürecinde hastane ortamında bulunmanın da ayrı bir stresör olduğu aşikardır. Amaç: Bu çalışmanın amacı, pandemi sürecinde günübirlik cerrahi geçiren hastaların preoperatif anksiyete düzeylerini değerlendirmektir. Gereç ve yöntemler: Kesitsel tipteki çalışma, günübirlik cerrahi için hastaneye başvuran 310 hastayı içermektedir. Veriler, olgu rapor formu ve Durumluk-Sürekli Kaygı Ölçeği (STAI I-II) aracılığı ile toplandı. Verilerin analizi IBM SPSS istatistik 25.0 paket programı ile yapıldı. Normallik dağılımı Shapiro-Wilks testi ile incelendi. Normal dağılım gösteren değişkenlerin analizinde parametrik ve normal dağılım göstermeyen verilerin analizinde nonparametrik testler uygulandı. Değişkenler arası ilişkiler Pearson korelasyon testi ve çoklu doğrusal regresyon modeli ile araştırıldı. Bulgular için kabul edilen anlamlılık düzeyi α<0.05’tir. Bulgular: Araştırma grubunun yaş ortalamasının 46.61±11.98 olduğu, %58.4’ünün kadın olduğu, %59.7’sinin ilköğretim mezunu olduğu ve %44.2’sinin en az bir kronik hastalığı bulunduğu belirlendi. Katılımcıların %21.6’sı COVID-19 hastalığı geçirmiştir. Günübirlik cerrahi girişimler sırasında katılımcıların %75.5’ine lokal anestezi uygulanmış, %25.2’si kadın doğum kliniğine başvurmuştur. Durumluk Kaygı ölçeği puan ortalaması 46.25±11.37 olup %61.3’ünün orta düzeyde kaygısı bulunmaktadır. Sürekli Kaygı ölçeği puan ortalaması 45.68± 8.59 olup %69.4’ünün orta düzeyde kaygısı bulunmaktadır. Durumluk kaygı düzeyi arttıkça sürekli kaygı düzeyi de artmaktadır (p<0.05). Durumluk kaygı düzeyi; yaş, eğitim durumu, çocuk sahibi olma, kronik hastalığı olma, hipertansiyon varlığı, COVID-19 tanısı alma ve pandemi sürecinde bir işte çalışma durumlarından etkilenmektedir (p<0.05). Sürekli kaygı düzeyi; eğitim durumu, COVID-19 tanısı alma, pandemi sürecinde bir işte çalışma ve cerrahi girişim sırasında uygulanan anestezi tipinden etkilenmektedir (p<0.05). Sonuç ve öneriler: Pandemi sürecinde günübirlik cerrahi uygulanan hastaların anksiyetesinin orta düzeyde olduğu belirlendi. Eğitim durumu, COVID-19 tanısı alma ve pandemi sürecinde bir işte çalışma durumları hem durumluk hem de sürekli kaygı düzeyini etkilemektedir. Durumluk kaygı düzeyi arttıkça sürekli kaygı düzeyi de artmaktadır. İnsanların pandemi ile nasıl başa çıktıklarını ve pandemi sırasında hangi psikososyal desteklere ihtiyaç duyduklarını anlamak için nitel araştırmalara ihtiyaç vardır. Veriler gelecekteki pandemi yönetimi için çok önemlidir.
Evolution versus Design: Template-Directed Self-Assembly of Peptides to Artificial Proteins (TASP)
Authors: Mutter Manfred , Tuchscherer Gabriele
Published: May 2022

Protein design and mimicry combines elements of synthetic organic chemistry with structural and functional aspects of biological relevance in a unique way. Due to progress in this interdisciplinary research field, access to molecules featuring some essential properties of native proteins
appears to be within reach, enabling the complex mechanisms in molecular recognition processes to be deciphered. Since its introduction by the authors, the template approach in protein de novo design (Template Assembled Synthetic Proteins, TASP) has experienced a broad conceptual diversification.
Starting from today's state-of-the-art in protein design, we present here some ongoing work in the Lausanne laboratories focusing on the use of regioselectively addressable templates and TASP scaffolds for addressing fundamental questions in peptide assembly, protein folding and mimicry. It
is shown that the developed concepts can ideally reconcile evolutionary and rational design principles for creating molecules of biological and therapeutic interest.
Molecular-Based Magnetism in High-Spin Molecular Clusters and Three-Dimensional Networks Based on Cyanometalate Building Blocks
Authors: Pilkington Melanie , Decurtins Silvio
Published: May 2022

The field of molecule-based magnets is a relatively new branch of chemistry, which involves the design and study of molecular compounds that exhibit a spontaneous magnetic ordering below a critical temperature, Tc. One major goal involves the design of materials with tuneable Tc's for specific applications in memory storage devices. Molecule-based magnets with high magnetic ordering temperatures have recently been obtained from bimetallic and mixed-valence transition metal ?-cyanide complexes of the Prussian blue family. Since the µ-cyanide linkages permit an interaction between paramagnetic metal ions, cyanometalate building blocks have found useful applications in the field of molecule-based magnets. Our work involves the use of octacyanometalate building blocks for the self-assembly of two new classes of magnetic materials namely, high-spin molecular clusters which exhibit both ferromagnetic intra- and intercluster coupling, and specific extended network topologies which show long-range ferromagnetic ordering.