bluuebunny/crossref_metadata_2025 huggingface dataset:
Adolph Friedrich Erdmann von Menzel
Authors: Tejedor Estupiñan Ricardo Alonso
Published: February 2018

Nació el 8 de diciembre de 1815 en Breslavia, ciudad donde se originó el alzamiento de los prusianos en 1813 y que daría lugar a la guerra de independencia alemana en contra de Napoleón I; allí mismo, desde la primera mitad del siglo XIX se inició un imparable desarrollo industrial y económico que llevó a la ciudad a convertirse en una de las más grandes e importantes de Alemania, dicho momento y espacio fueron propicios para fertilizar la genialidad de un hombre que dedicaría toda su vida a retratar en diferentes técnicas, escenas y personajes  de la vida cotidiana en su país.
İzmir, Çanakkale ve Balıkesir İllerinde Keçi Sütü Maliyetinin Saptanması Üzerine Bir Araştırma
Authors: ENGİNDENİZ Sait , AKTÜRK Duygu , SAVRAN A. Ferhan , KOŞUM Nedim , TAŞKIN Turgay , KESENKAŞ Harun , UZMAY Ayşe , GÖKMEN Mukadderat , ÖZTÜRK Görkem
Published: February 2018

 

Bu araştırmanın temel amacı; İzmir, Çanakkale ve

Balıkesir illerinde,  üreticilerden

derlenen veriler ışığında keçi sütü maliyetini saptamaktır. Araştırmada kapsama

alınan illerde tabakalı (oransal) tesadüfi örnekleme ile 234 keçi

yetiştiriciliği işletmesinden veriler derlenmiştir. Keçi yetiştiriciliği yapan

işletmelerin 2013 yılı faaliyetleri hayvan sayısına göre üç grup altında analiz

edilmiştir. Birinci grubu 75 baş ve daha az, ikinci grubu 76-150 baş, üçüncü

grubu da 151 baş ve daha fazla hayvana sahip işletmeler oluşturmaktadır.

İşletmelerde ortalama hayvan mevcudu 128.23 baştır ve hayvanların %44.90’ını

Kıl keçi, %44.71’ini Sanen x Kıl melezi genotipler oluşturmaktadır. İşletme

başına ortalama süt üretimi 26251.82 kg, hayvan başına ortalama günlük süt

üretimi ise 1.65 kg olarak saptanmıştır. Üretici eline geçen ortalama süt

fiyatı 1.31 TL/kg’dır. İşletmelerde ortalama süt maliyeti 0.75 TL/kg olarak

saptanmıştır. Desteklerden yararlanılmaması durumunda maliyet 0.98 TL/kg

olmaktadır. 
GC/MS Analysis and Antimicrobial Activity of The Volatile Compounds From Dianthus carmelitarum Reut. ex Boiss and Dianthus calocephalus Boiss. Grown in Turkey
Authors: YÜCEL Tayyibe Beyza , YAYLI Nurettin
Published: February 2018

The chemical

composition of the essential oils of Dianthus

carmelitarum Reut. ex Boiss. and Dianthus

calocephalus Boiss. were identified by GC-FID and GC-MS. Essential oils of D.

carmelitarum  and D. calocephalus were obtained from the

whole part of  fresh plant by

Clevenger-type distillation. Analyses of the essential oils gave 40 and 35 compounds,

constituting over 86.58% and 76.45% in the total, respectively. Main components

in D. carmelitarum were heneicosane (11.69%),

docosane (10.52%), tetracosane (9.20%) and pyhtol (4.62%). Whereas, 4,4-dimethyl-2-pentene

(17.65%), phytol (15.47%), pentacosane (4.38%) and hexahydrofarnesyl acetone (3.08%)

were the major constituents in D.

calocephalus. Antimicrobial activity of the essential oils obtained from D. carmelitarum  and D.

calocephalus  were evaluated against nine

gram positive, gram negative bacteria and  the yeast-like fungi using  disc diffusion and broth microdilution

methods. The essential oils of D.

carmelitarum and D. calocephalus

showed good antimycotic activity against Candida

albicans having the MIC values of 668 µg/mL and 1041 µg/mL, respectively. 
Nergis ve Sümbül Yetiştiriciliğinde Yabancı otların Belirlenmesi ve Mücadele Yöntemlerinin Araştırılması
Authors: KAÇAN Koray , ÖZKUL Çetin , SOKAT Yıldız
Published: February 2018

Bu çalışma 2013-2014 yıllarında
İzmir ili Karaburun ilçesinde nergis ve sümbül tarlalarında sorun olan yabancı
otların ve mücadelelerinin belirlenmesi amacıyla gerçekleştirilmiştir. Yabancı
ot survey çalışmasında en fazla rastlanma sıklığına sahip olan yabancı otun Oxalis pes-caprae L. (% 94.7) olduğu belirlenmiştir. Bu yabancı ot ile
birlikte Erodium
cicutarium (L.) L'Her. ex Aiton (% 52.0),  Bromus
tectorum L. (% 50.0), Hordeum murinum L. (% 44.74) ve Gallium
aparine L. (% 44.7) ilk
beş sırayı almışlardır. Rastlanma sıklığı en çok olan yabancı ot türü, ekşi ot
(Oxalis pes-caprae L.) olup istilacı yabancı ot
olmasından dolayı ileriki yıllarda daha fazla yayılım göstereceği tahmin
edilmektedir. Yabancı ot yoğunluğu bakımından en yoğun yabancı ot Oxalis pes-caprae L. (115.42 Adet/m2) olarak bulunmuştur. Bunu
sırasıyla, Hordeum murinum L. (34.38 Adet/m2), Avena sterilis L. (26.29 Adet/m2), Trifolium repens L. (14.29 Adet/m2), Bromus tectorum L. (11.42 Adet/m2), (L.) L'Her. ex Aiton (8.47 Adet/m2)
izlemişlerdir. Mücadele çalışmalarında 4 farklı etkili maddeli herbisit
(Pendimethalin, Oxyfluorfen, Picloram+2,4 D, Aclonifen) tesadüf blokları deneme
desenine göre 3 tekerrürlü olarak değerlendirmeye alınmıştır. Herbisitlerin
yabancı ot kuru ağırlıklarına etkileri incelediğimizde ise, en yüksek etki,
Oxyfluorfen herbisitinden (% 43.20) elde edilmiştir. Bu etkiyi en yakın etki
olarak Picloram + 2,4 D (%43.18) izlemiştir. Diğer bir etkili uygulama olan
Aclonifen etkileri (% 38.10) ve Phendimethalin (% 36.00), Solarizasyon  (% 5.60) uygulamaları olmuştur.
Review Article: URIC ACID HOMEOSTASIS AND DISTURBANCES
Authors: Karwur Ferry Fredy , Pujiastuti Dwi Rahayu
Published: February 2018

This review examined the homeostasis of uric acid in human body and analyzed recent studies of the affecting major variables. Normal uric acid concentration in male is 3.5-7.2 mg/dL and in female is 2.6-6 mg/dL. Daily turnover of normal uric acid ranges from 498-1392 mg/day, miscible pool is 767-1650 mg, reabsorption is 8064 mg/day, renal excretion is 262-620 mg/day and intestine 186-313 mg/day. The dynamics of uric acid is influenced by factors of food, drink, age, history of disease, and genetic. High purine dietary consumption increases blood uric acid by 1-2 mg/dL, 213-290 g/day fructose drinks increases 0.52-1.7 mg/dL, 1.5 g/kgBW sucrose increases 0.61 mg/dL, and 10-20 ml/kgBW beer increases 0.50-0.92 mg/dL. The ABCG2 gene plays a role in bringing uric acid out of the body by 114.31-162.73 mg/dL, SLC2A9 of 5.43-20.17 mg/dL, and SLC22A12 of 5.77-6.71 mg/dL. The data described the homeostasis of uric acid and the magnitude of the impact of environmental (consumption of food, beverages, and lifestyle) and genetic factors. Understanding uric acid homeostasis and its disturbances is important in managing diseases as a consequence of hyperuricemia and hypouryscemia
Ulnar Collateral Ligament Injuries of the Elbow in the Throwing Athlete
Authors: Raducha Jeremy E. , Gil Joseph A. , Harris Andrew P. , Owens Brett D.
Published: February 2018

Update

This article was updated on February 26, 2018, because of a previous error. On pages 1 and 7, in the author byline section, the authors' names that had read “Andrew Harris” and “Brett Owens” now reads “Andrew P. Harris” and “Brett D. Owens.”

An erratum has been published: JBJS Reviews. 2018 Feb;6(2):e7.

* The anterior cord of the ulnar collateral ligament is the portion most commonly injured and is what is reconstructed.

* The ulnar collateral ligament is under the most stress during the late cocking and early acceleration phases of throwing.

* Magnetic resonance imaging is necessary to properly diagnose ulnar collateral ligament insufficiency.

* Reconstruction is the primary treatment method for athletes. The modified Jobe and Docking techniques are the most commonly used operative techniques.

* Athletes are able to return to competition, on average, between 12 and 20 months after the procedure with typically excellent outcomes.
ANALISIS KORELASI DAN REGRESI DINAMIKA POPULASI HAMA DAN MUSUH ALAMI PADA BEBERAPA VARIETAS UNGGUL PADI SETELAH PENERAPAN PHT DI KABUPATEN BONE PROVINSI SULAWESI SELATAN
Authors: Ilyas Asriyanti
Published: February 2018

Different types of rice pests, have been reported. The explosions and a potential pests are Rice Stem Borer (Tryporiza

sp.), Brown Planthoppers (Nilaparvata lugens), Green Leafhoppers (Nephotettix virescens), and Rats (Rattus sp.), wich

an obstacle in creating stability of rice production in Bone. In rice ecosystem, natural enemies of arthropod predators

are most instrumental in suppressing the pest population. Fluctuation in population density of natural enemies, affecting

pests presence. Efforts to suppress pest proportions through IPM, is a strategy of lowering the level of pests and damage

to rice crops. This study aims to identify and measure the relationship strength between pests and natural enemies

populations in some rice varieties after IPM, using correlation and regression analysis. Observations conducted in Bone,

from May to August 2012, with 2 observed variables, pests and natural enemies populations in Inpari 6, Inpari 10, Inpari

16, Ciherang, Cigelis, and Mekongga. Data analysis were performed using correlation and regression analysis. The

results showed a high degree of correlation between pest and natural enemies (predators) populalions, characterized by

a positive correlation coefficient (0.957) and significant at the level of 0.01, where each increase in the intensity of pest

populations, will be followed by increase in the number of natural enemies captured.
PENYUSUNAN ALTERNATIF MODEL KELEMBAGAAN KREDIT USAHA PERTANIAN DI PERDESAAN
Authors: Hartono Rudi , Hadi Setia , Juanda Bambang , Rusastra I Wayan
Published: February 2018

Berbagai jenis pembiayaan di sektor pertanian, baik yang formal maupun non formal telah diaplikasikan pada masyarakat, tetapi dalam pelaksanaan pembiayaan tersebut masih menghadapi beberapa kendala dan hambatan. Kegagalan kredit untuk pertanian selama ini umumnya disebabkan kerena skim yang ada selama ini tidak menyentuh “petani pelaku”, kurangnya penyiapan “petani pelaku” sebagai target group, banyaknya kebocoran kredit dan mekanisme kredit yang tidak tepat. Saat ini diharapkan ada model kelembagaan yang dapat memberikan solusi keterbatasan petani pada akses permodalan. Penelitian bertujuan untuk menganalisis dan merumuskan model kelembagaan pembiayaan untuk mendukung usaha pertanian di perdesaan. Penelitian dilaksanakan di Kabupaten Badung Propinsi Bali, Kabupaten Sleman Daerah Istimewa Yogyakarta dan Kabupaten Seluma Propinsi Bengkulu dari bulan Juni 2011 sampai April 2012. Sumber data terdiri dari data sekunder dan data primer. Total responden sebanyak 90 orang penerima dana PUAP yang penggunaannya untuk usahatani padi. Hasil penelitian menunjukkan bahwa model kelembagaan kredit untuk usaha pertanian perdesaan dirumuskan dalam tiga tingkatan yaitu Model Penumbuhan yang terdiri dari a) Pendampingan dari penyuluh pada petani dalam menyusun rencana peminjamannya sedangkan pendampingan pada pengelola dana simpan pinjam dilakukan oleh petugas pengelola dana kelompok; b) Agunan bagi peminjam diganti dengan rekomendasi dari aparat desa; c) Adanya sangsi kelompok/desa/sosial bagi peminjam yang tidak mengembalikan pinjamannya; d) Hanya melayani peminjam yang berasal desa setempat; e) Pengelolaan dana simpan pinjam dilakukan oleh manajemen yang terpisah dengan kepengurusan gapoktan, namun pengawasan dilakukan oleh pengurus gapoktan, dan f) Adanya insentif untuk pengelola dana simpan pinjam. Model Pengembangan merupakan peningkatan dari model penumbuhan dengan tambahan beberapa elemen yaitu a) Adanya Tabungan khusus untuk pemupukan modal kelompok; b) Insentif diberikan juga untuk anggota yang mempunyai tabungan khusus; c) Pengawasan dilakukan oleh pengurus gapoktan dan aparat desa. Sedangkan Model Mandiri merupakan peningkatan dari model penumbuhan dan pengembangan dengan tambahan elemen yaitu Lembaga keuangan harus mempunyai Badan Hukum dan Izin usaha agar dapat melakukan ekspansi kerjasama usaha dengan pihak lain.
PENGARUH INTENSIFIKASI USAHATANI PADI TERHADAP PENINGKATAN PRODUKSI DAN PENDAPATAN PETANI DI KABUPATEN MANOKWARI
Authors: Sianipar Jeffry E. , Sankarto Bambang S.
Published: February 2018

Peningkatan produktivitas padi telah dicapai di Kabupaten Manokwari sejak 2008 tetapi masih sangat rendah (6,5%). Untuk meningkatkan produksi, pemerintah daerah telah berusaha untuk mengoptimalkan pemanfaatan sumber daya yang tersedia dan juga inovasi teknologi. Penelitian bertujuan untuk mengetahui dan menganalisis faktor-faktor yang memengaruhi produksi padi dan pendapatan petani. Penelitian dilakukan di Distrik Prafi, Distrik Masni dan Distrik Warmare, Kabupaten Manokwari. Total sampel populasi yang diambil sebanyak 90 petani yang setiap kabupatennya diambil sebanyak 30 orang, dan kemudian dikelompokkan ke dalam petani transmigran dan petani lokal. Data dianalisis menggunakan fungsi produksi dan fungsi pendapatan Cobb-Douglass yang selanjutnya diestimasi menggunakan metode Ordinary Least Square (OLS). Hasil penelitian menunjukkan bahwa pengaruh intensifikasi usaha pertanian terhadap produksi padi dan pendapatan petani, terbaik diperoleh oleh petani transmigran dibanding petani setempat.

 

 
Effect of Cocoa Liquor Temperature To The Yield And Fat Content Of Cocoa Powder Fermented and Unfermented Cocoa.
Authors: Septianti Erina , Arif Abdullah Bin
Published: February 2018

Cocoa has become one of the strategic export commodities which accounted for the fourth largest foreign exchange after oil palm, rubber, and coconut. Indonesian cocoa production is significantly increasing, but the quality is still unsatisfactory. This will give conveying pathern of low quality of Indonesian cocoa in international markets. The producers need to improve the cocoa beans quality and start selling intermediate to final processed product. The fermentation process is an essensial stage of cocoa beans processing to guarantee a good flavor and aroma. Pressing process is also a very important step of process in determining the quality of cocoa.This research was aimed to determine the influence of cocoa liquefied temperature on the fat yield and fat content of the cocoa powder obtained from pressing of cocoa paste with a hydraulic pressing system. The result of this study is expected to provide information on the effectiveness of pressing at several cocoa paste temperatures. The treatments was arranged in Factorial Designwith 3 treatments of cocoa paste temperature (room temperature (± 30oC), 40oC and 50oC), and 3 replication for fermented and without fermentation cocoa. The results of this study show that effective temperature on compression of paste is at a temperature of 50 oC which generated the most fat yield and the lowest fat content of cocoa powder.

 

PENGARUH SUHU PEMASTAAN TERHADAP RENDEMEN DAN KADAR LEMAK BUBUK KAKAO HASIL PENGEMPAAN DARI BIJI KAKAO FERMENTASI DAN NON FERMENTASI

Kakao telah menjadi salah satu komoditas ekspor strategis yang menyumbang devisa negara terbesar keempat setelah kelapa sawit, karet, dan kelapa. Produksi biji kakao Indonesia secara signifikan terus meningkat, namun mutu yang dihasilkan masih kurang memuaskan. Hal tersebut akan menurunkan citra kakao Indonesia di pasaran luar negeri. Keadaan ini menuntut produsen kakao untuk terus meningkatkan mutu biji kakao dan mulai mengalihkan perhatian untuk tidak hanya menjual kakao dalam bentuk biji, tetapi juga dalam bentuk bahan jadi maupun setengah jadi. Proses fermentasi merupakan tahapan pengolahan biji kakao yang vital dan mutlak untuk menjamin dihasilkannya citarasa maupun aroma cokelat yang baik. Proses pengempaan juga merupakan proses yang sangat penting dalam menentukan mutu kakao. Penelitian ini bertujuan untuk mengetahui pengaruh suhu pasta kakao terhadap rendemen lemak dan kadar lemak bubuk kakao dengan pengempaan sistem hidrolik. Perlakuan disusun dalam Rancangan faktorial, dengan 3 perlakuan suhu pasta yaitu suhu ruang (± 30 oC), suhu 40 oCdan suhu 50 oC masing-masing 3 ulangan untuk jenis bahan kakao fermentasi dan tanpa fermentasi. Hasil penelitian menunjukkan suhu efektif pada pengempaan yang dilakukan adalah pengempaan pasta pada suhu 50 oC dimana dihasilkan rendemen lemak paling banyak dan kadar lemak bubuk kakao paling rendah.
Construction, Validation, and Application of Digital Oil: Investigation of Asphaltene Association Toward Asphaltene-Precipitation Prediction
Authors: Sugiyama S.. , Liang Y.. , Murata S.. , Matsuoka T.. , Morimoto M.. , Ohata T.. , Nakano M.. , Boek E. S.
Published: February 2018

Digital oil, a realistic molecular model of crude oil for a target reservoir, opens a new door to understand properties of crude oil under a wide range of thermodynamic conditions. In this study, we constructed a digital oil to model a light crude oil using analytical experiments after separating the light crude oil into gas, light and heavy fractions, and asphaltenes. The gas and light fractions were analyzed by gas chromatography (GC), and 105 kinds of molecules, including normal alkanes, isoalkanes, naphthenes, alkylbenzenes, and polyaromatics (with a maximum of three aromatic rings), were directly identified. The heavy fraction and asphaltenes were analyzed by elemental analysis, molecular-weight (MW) measurement with gel-permeation chromatography (GPC), and hydrogen and carbon nuclear-magnetic-resonance (NMR) spectroscopy, and represented by the quantitative molecular-representation method, which provides a mixture model imitating distributions of the crude-oil sample. Because of the low weight concentration of asphaltenes in the light crude oil (approximately 0.1 wt%), the digital oil model was constructed by mixing the gas, light-, and heavy-fraction models. To confirm the validity of the digital oil, density and viscosity were calculated over a wide range of pressures at the reservoir temperature by molecular-dynamics (MD) simulations. Because only experimental data for the liquid phase were available, we predicted the liquid components of the digital oil at pressures lower than 16.3 MPa (i.e., the bubblepoint pressure) by flash calculation, and calculated the liquid density by MD simulation. The calculated densities coincided with the experimental values at all pressures in the range from 0.1 to 29.5 MPa. We calculated the viscosity of the liquid phase at the same pressures by two independent methods. The calculated viscosities were in good agreement with each other. Moreover, the viscosity change with pressure was consistent with the experimental data. As a step for application of digital oil to predict asphaltene-precipitation risk, we calculated dimerization free energy of asphaltenes (which we regarded as asphaltene self-association energy) in the digital oil at the reservoir condition, using MD simulation with the umbrella sampling method. The calculated value is consistent with reported values used in phase-equilibrium calculation. Digital oil is a powerful tool to help us understand mechanisms of molecular-scale phenomena in oil reservoirs and solve problems in the upstream and downstream petroleum industry.
Revival of Green Conformance and IOR/EOR Technologies: Nanosilica Aided Silicate Systems - A Review
Authors: Lakatos I. , Lakatos-Szabo G. , Szentes G.
Published: February 2018

Reservoir conformance control (RCC) might be fundamental designingprofitable production technology in oilfields. Appropriate application of RCC methods can significantly results inimproved IOR/EOR throughreduced water production and profile correction. In the past decades, numerous techniques were extensively applied with these goals including macro- and microgels, emulsions, sols, crystalline compounds, etc. Surprisingly, the use of silicates was not really appreciated by the operators despite the fact that silicates were proposed for chemical EOR and profile control already in 1922. In the past decades, the silicate technology has a revival because of their outstanding features and these methods are superior to other gel technical solution. The review is summarizing both the old and the new results of laboratory research and the case histories. Recently, emblematic professionals proposed the silicate gels as efficient alternatives to other gel technologies. As a result, the attitude towards the extensive use of silicates in oil fields changed. Therefore, the presentation overviews the silicate conformance treatments and its advanced hybrid systems. They were used more than hundred times in Hungary, Serbia, Norway, USA, Oman, and other countries for water shutoff, profile correction, restriction of gas conning, mitigation of vertical CO2 migration in wells, remediation of leak-off by fractured casing, stimulation of wells operating in harsh environment, and mobility control in CO2 flooding.

The presentation summarizes the results of pilots and routine applications, and critically analyzes the lessons to learn. Base on the publications disseminated until now it can be concluded that the field jobs demonstrate outstanding statistics. It will also be shown that the diverse silicate RCC methods may attract attention because they can be efficiently used with high flexibility in all types of porous and fractured reservoirs. The in-situ formed silicate gels have excellent thermal stability up to 150°C, the chemicals are available at low price, the job needs simple surface facility, customary human force, and the methods are environmental friendly. Consequently, the silicate methods may open new vistas in brown field operations curing problems arising at oil and gas fields even in time of volatile oil and gas price.
Análisis multicriterio SIG basado en momentos de orden superior normalizados para el cálculo de superficies de viabilidad ambiental
Authors: Gómez Colorado Oscar Alberto , Horfán Álvarez Daniel , Londoño Ciro Libardo Antonio
Published: February 2018

El presente estudio plantea una metodología para generar áreas de criticidad y niveles de susceptibilidad ambiental aptas para el trazado o localización de proyectos de infraestructura, con un alto grado de certidumbre comparado con los métodos convencionales basados en las funciones de máximos, media aritmética y promedio ponderado. La metodología se basa en la superposición espacial de variables físicas, ambientales y socioeconómicas que miden el impacto en el territorio ante el paso o ubicación del proyecto de infraestructura; aplicando el método de análisis estadístico denominado “momentos de orden superior” con un factor exponencial de normalización, propuesto por los autores. El modelo de análisis propuesto aplica principalmente en el Diagnóstico Ambiental de Alternativas (DAA) de proyectos lineales y concentrados, exigido por el Ministerio de Ambiente y Desarrollo Sostenible  (MINAMBIENTE), en Colombia. El modelado espacial de los datos y las operaciones de superposición de capas de información, se realizaron a través de la herramienta Model Builder y la calculadora de mapas del software Arcgis.   El análisis numérico y espacial realizado a través del SIG representa la interacción de los diferentes componentes bióticos, físicos y sociales (económicos, políticos y culturales), que inciden en la viabilidad del trazado o ubicación  de un proyecto de infraestructura (vías, oleoductos, líneas de transmisión de energía, centrales hidroeléctricas, rellenos sanitarios, entre otros).Los resultados obtenidos demuestran como la superficie de susceptibilidad general, calculada con el método de momentos de orden superior normalizado, permite una toma de decisiones adecuada, toda vez que puede ajustarse con mayor aproximación a las diferentes restricciones ambientales de la región.
Comparación de un control lineal y no lineal en un levitador magnético
Authors: Castro Beltrán Jonathan Smith , Vergara Ramírez Carlos Felipe , Herrera Guayazan Joan Stiven
Published: February 2018

El artículo presenta los diseños y resultados de dos controladores tipo SISO de posición para un levitador magnético convencional, con la motivación de comparar las dinámicas de los sistemas posterior a la implementación de ambos métodos de control. Para el diseño de los controladores se obtuvo el modelo matemático aproximado de un levitador magnético a partir de características estáticas, de fuerza electromagnética e inductancia. Una vez establecido el modelo matemático se planteó una ley de control lineal a partir de una realimentación de estados con integrador, estimando la velocidad y corriente. Para el diseño del control no lineal se propuso una ley de control de tipo linealización entrada salida. Por último, se comparó la dinámica del sistema con los controladores implementados y se realizaron modificaciones de masa para verificar la robustez de los controladores, además de perturbaciones tales como fuerzas externas y ruido de tipo eléctrico. Finalmente, fue posible concluir que el controlador lineal tiene una respuesta satisfactoria en términos de error de estado estacionario, añadiendo un menor costo de procesamiento en comparación al controlador no lineal.
ABC Transporters: Regulation and Association with Multidrug Resistance in Hepatocellular Carcinoma and Colorectal Carcinoma
Authors: Ceballos María Paula , Rigalli Juan Pablo , Ceré Lucila Inés , Semeniuk Mariana , Catania Viviana Alicia , Ruiz María Laura
Published: February 2018

:

For most cancers, the treatment of choice is still chemotherapy despite its severe adverse effects, systemic toxicity and limited efficacy due to the development of multidrug resistance (MDR). MDR leads to chemotherapy failure generally associated with a decrease in drug concentration inside cancer cells, frequently due to the overexpression of ABC transporters such as P-glycoprotein (P-gp/MDR1/ABCB1), multidrug resistance-associated proteins (MRPs/ABCCs), and breast cancer resistance protein (BCRP/ABCG2), which limits the efficacy of chemotherapeutic drugs. The aim of this review is to compile information about transcriptional and post-transcriptional regulation of ABC transporters and discuss their role in mediating MDR in cancer cells.

:

This review also focuses on drug resistance by ABC efflux transporters in cancer cells, particularly hepatocellular carcinoma (HCC) and colorectal carcinoma (CRC) cells. Some aspects of the chemotherapy failure and future directions to overcome this problem are also discussed.
The structural equation modeling of reading interest psycho-behavioural constructs: How are they related across different modes of reading?
Authors: Putro Nur Hidayanto Pancoro Setyo , Lee Jihyun
Published: February 2018

The present study examines the relationships between the psycho-behavioral constructs underlying undergraduate students’ reading interest. The a priori framework for conceptualizing the sub-components of reading interest is based on two modes of reading (printed-text-based and also Internet-based), and three types of psycho-behavioral motives/intentions of reading (affective, cognitive, and behavioral). Participants in this study were students (M = 20.14 years old) from an Indonesian university (n = 993). Exploratory and confirmatory factor analyses show the salience of 10 factors across reading modes and psycho-behavioral domains of reading. The most accept-able SEM models that explore the relationships among the sub-components of reading interest have the student reading interest in the print mode preceded interest in reading online materials. Implications of these findings are discussed for theory development and practice.
Practitioner-informed improvements to early childhood intervention performance checklists and practice guides
Authors: Dunst Carl J. , Hamby Deborah W. , Wilson Linda L. , Espe-Sherwindt Marilyn , Nelson Donna E.
Published: February 2018

Results from four early childhood practitioner field tests of performance checklists and early intervention practice guides are reported. Findings from the first field test were used to make changes and improvements in the checklists and practice guides evaluated in the second and third field tests, and findings from the latter two field tests were used to improve the checklist and practice guide evaluated in the fourth field test. Results indicated that changes made in response to practitioners’ suggestions and feedback were associated with (1) progressive increases in the practitioners’ social validity judgments of the checklists, practice guides, and checklist-practice guide correspondence, and (2) progressive decreases in the number of practitioner suggestions and feedback for improving the early intervention materials. The field-test research demonstrates the importance of practitioner input, suggestions, and feedback for improving the usefulness of early childhood intervention practices.
ASSESSMENT OF THE NUTRITIONAL BEHAVIOUR AMONG COLLEGE STUDENTS-A SURVEY
Authors: Begum S. K. Shafiya , Kavuri Naga Swathi Sree , Uppalapati Mohan Chand , Polavarapu Divya
Published: February 2018

Objective: To assess the nutritional behaviour among college students.Methods: A prospective observational survey was conducted randomly among college students in Guntur. A self-administered data collection form was designed to understand the nutritional behaviour of the subjects.Results: A total of 300 subjects were included in the study, among them 225(75%) were females and 75(25%) were males. The survey revealed that most of them skipped their meals. A majority of 184(61.33%) students opted for high-fat diet and 268(89.33%) opted for starch-rich foods. A total of 222(74%) students usually eat four different varieties of vegetables but only 71(23.66%) of them eat fruits in each week.Conclusion: From this study, it was evident that majority of students have poor dietary habits. Lack of awareness on balanced diet and due to their busy schedules, teenagers were not maintaining a proper diet. This could be reduced by bringing minimum awareness on dietary habits to them. Taking proper diet is very essential to reduce the risk of diseases in future and to improve nourishment.
ETHNOBOTANICAL USES, PHYTOCHEMISTRY AND PHARMACOLOGICAL ACTIVITIES OF PEPEROMIA PELLUCIDA (L.) KUNTH (PIPERACEAE)-A REVIEW
Authors: L. Raghavendra H. , R. Prashith Kekuda T.
Published: February 2018

Peperomia pellucida (L.) Kunth is a herb belonging to the family Piperaceae. In this review, an extensive literature survey was carried out to compile information available on medicinal uses, phytochemistry and pharmacological properties of P. pellucida. The plant is used as food, flavoring agent and as medicine. The plant is used as medicine for treating various ailments or disorders such as asthma, rheumatism, wound, fever, stomach problems, kidney infection, hemorrhoid pain, joint pain, hypertension, diarrhea, snake bite and measles. The plant contains phytochemical groups such as alkaloids, flavonoids, saponins, terpenoids, steroids and glycosides. Compounds such as dill apiole, phytol, stigmasterol, sitosterol, secolignans, tetrahydrofuran lignans, highly methoxylated dihydronaphthalenone, peperomins, sesamin and isoswertisin have been identified in the plant. Studies have shown that the plant exhibited several pharmacological activities such as antimicrobial, antioxidant, anti-angiogenic, anti-inflammatory, analgesic, antipyretic, neuropharmacological, antisickling, anticancer, enzyme inhibitory, antiulcer, hypotensive, immunostimulatory, fracture healing and antidiabetic activities which support the traditional use of the plant. Purified chemicals from the plant have also shown to exhibit certain pharmacological activities such as antiulcer, anticancer and antimicrobial activity. By this extensive literature review, it can be concluded that P. pellucida can be utilized as a promising candidate for developing newer drugs with potent pharmacological activities.
SERUM LIPID LEVELS IN PERIODONTITIS PATIENTS: A CASE-CONTROL STUDY
Authors: Ahmed M. A. Adil , D. Judyangel , R. Rajathi , S. Rafiya , Kumari Pooja , D. Pragadeeswari
Published: February 2018

Objective: We aimed to evaluate serum lipid levels in periodontitis patients and compared with healthy subjects.Methods: A case-control study was conducted among 30 participants in the age group of 35-60 y, including 15 subjects in case group with community periodontal index (CPI) score of ≥2 and 15 subjects in the control group with a CPI score of ≤ 1 based on their periodontal status. Fasting blood samples were taken for measurement of lipid profiles, including total cholesterol, triglyceride (TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL) using an enzymatic method. Odds ratio and independent t-test at *p=0.05 significance level were calculated.Results: Periodontitis patients were 4.1 times at risk to have high triglyceride, 1.3 times at risk to have high total cholesterol and 0.3times at risk to have higher HDL. Independent t-test showed higher total cholesterol/HDL ratio (*p=0.033) and lowered HDL levels (*p=0.027) in periodontitis patients.Conclusion: Periodontitis group has significantly higher total cholesterol/high-density lipoprotein ratio and lower high-density lipoprotein levels when compared to the healthy group.
Teaching English Using Poetry: An Alternative to Implement Contextual Teaching and Learning
Authors: Samanik Samanik
Published: February 2018

This paper describes poetry as an alternative to implement Contextual Teaching and Learning (CTL). CTL places learning and learning activities in a real-life context, incorporating not only what is learned but also why students should learn it. Meanwhile, poetry is chosen for its authenticity, in which, all nations have their own record on poetry. The classroom activities which involve poetry are poetry production (writing), poetry performance (reading), and poetry appreciation (speaking). By using poetry, learning processes are expected to meet the seven main components of effective learning: constructivism, questioning, inquiry, learning community, modeling, and authentic assessment. Moreover, the learning process can develop not only language skills but also critical thinking skill.

 Keywords: Contextual Teaching and Learning (CTL), poetry, components of ideal teaching and learning
A Strategic Approach to Target Capital Investment on Facility Assets: Literature Review
Authors: Rincon Jorge L. , Lavy Sarel , Fernandez-Solis Jose. L
Published: February 2018

Analysis of a strategic planning framework, proposed by Edward Zielinski, focused on reducing operational costs in Facility Management (FM) through using long-term best practices in capital investment. This paper indicates how that framework may assist in the FM decision process of capital investment allocation. The framework structure is integrated through: (1) alignment of FM decisions to the organizational strategy; (2) measuring FM performance with a data-driven approach; and (3) standardization of budgeting processes as support for FM credibility. The authors use a Structured Literature Review to investigate how previous research of the topic and subtopics supports the framework's objectives. Emphasis on referenced case studies aims to investigate the applicability of this framework by FM practitioners. The framework is fully applicable to FM operations. The case study analysis suggests it is a powerful tool for supporting capital investment decisions in organizations. Benefits foreseen include: value creation through alignment of FM decisions to organizational goals, risk control in short-, mid- and long-term FM decisions, creation of structured procedures for FM data acquisition supporting stakeholders' decisions, increased FM credibility through budgeting process standardization, improvement of FM operations efficiency, and senior management awareness of FM priorities. This paper encourages FM practitioners to structure their daily operations by addressing the three most challenging aspects of this profession: understand the client, capitalize valuable knowledge, and secure funding.
Application of Lean Six Sigma to Improve Service in Healthcare Facilities Management: A Case Study
Authors: Shirey Will T. , Sullivan Kenneth Timothy , Lines Brian , Smithwick Jake
Published: February 2018

The purpose of this paper is to present a case study on the application of the Lean Six Sigma (LSS) quality improvement methodology to facilities management (FM) services at a healthcare organization. Research literature was reviewed concerning whether or not LSS has been applied in healthcare-based FM, but no such studies have been published. This paper aims to address the lack of an applicable methodology for LSS intervention within the context of healthcare-based FM. The Define, Measure, Analyze, Improve, and Control (DMAIC) framework was followed to test the hypothesis that LSS can improve the service provided by an FM department responsible for the maintenance and repair of furniture and finishes at a large healthcare organization in the southwest United States of America. Quality improvement curricula and resources offered by the case study organization equipped the FM department to apply LSS over the course of a five-month period. Qualitative data were gathered from pre- and post-intervention surveys while quantitative data were gathered with the Organization's computerized maintenance management system (CMMS) software. Overall, LSS application proved to be useful for the intended purpose. The authors proposes that application of LSS by other FM departments to improve their services could also be successful, which is noteworthy and deserving of continued research.
The impact of pain on functionality and health related quality of life in patients with knee osteoarthritis
Authors: Jurisic-Skevin Aleksandra , Grbovic Vesna , Stankovic Ivana , Radunovic Aleksandar , Nurkovic Jasmin , Milosevic Bojan , Cvetkovic Aleksandar , Divjak Ana , Vulovic Maja
Published: February 2018

Introduction/Objective. Pain, stiffness and limited mobility are the main factors that lead to difficulties in performing daily activities and are also responsible for the decline in the quality of life in people with knee osteoarthritis (OA). The aim of this study was to evaluate the functional capacity and health related quality of life (HRQoL) compared to pain in patients with knee OA, as well as to determine the correlation between these three clinical variables. Methods. The study involved 931 patients diagnosed with knee OA. In all patients, pain was evaluated by a short form of the McGill pain questionnaire (SF-MPQ), functional status was assessed using the Western Ontario and McMaster Universities Arthritis Index (WOMAC), while life quality was evaluated using the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). Results. The average age of patients was 61.21 ? 4.62 years, while 71.3% of them were women. The quality of life in patients with knee OA and all pain parameters contained in the SF-MPQ were highly statistically positively associated (p ? 0.01). In addition, the physical functioning was mostly affected by emotional pain (rho = -0.585). A high statistical correlation (p ? 0.01) was noted between stiffness and physical functioning from the WOMAC questionnaire and all of the parameters from the SF-MPQ. The physical functioning from the WOMAC questionnaire had the strongest correlation with total pain incorporated into the McGill questionnaire (rho = 0.530). Conclusion. Knee pain has a significant impact on functional capacity and HRQoL in patients with knee OA. Therefore, one of the main therapy goals for OA of the knee should be to reduce the pain in the affected knee, which can help to improve the functionality and HRQoL of these patients.
PERSEPSI PASIEN TENTANG ASPEK HUKUM PERIKATAN UPAYA (INSPANNING VERBINTENIS) DALAM TRANSAKSI TERAPEUTIK ANTARA DOKTER DENGAN PASIEN DI RSUD KOTA SALATIGA
Authors: Aribowo Bonifasius Nadya , Nurhayati B. Resti , Dahlan Sofyan
Published: February 2018

Konstruksi hukum dalam transaksi terapetik sudah terlembaga dalam ketentuan perundang-undangan nasional, namun persepsi pasien tentang aspek hukum perikatan upaya dalam transaksi terapeutik masih demikian beragam, tidak utuh, bahkan sebagian kabur. Penelitian ini bertujuan untuk melihat bagaimana persepsi pasien tentang aspek hukum perikatan upaya (inspanning verbintenis) dalam transaksi terapeutik antara dokter dengan pasien.Partisipan dalam penelitian ini adalah 15 orang pasien di RSUD Salatiga. Tehnik pengambilan sampel dengan menggunakan metode cluster random sampling dengan populasi : pasien yang sedang menjalani rawat inap berdasarkan perikatan atas kontrak di RSUD Kota Salatiga dalam jangka waktu satu bulan sejak pasien masuk dirawat inap di RSUD Kota Salatiga, Tehnik pengambilan data dengan studi lapangan lewat observasi dan wawancara yang mendalam (deep interview) secara terarah (directive interview), dengan analisa data secara kualitatif yang diuraikan secara deskriptif-naratif maupun menggunakan table maupun diagram secara statistik.Hasil yang didapatkan memperlihatkan bahwa 73,3 % responden memiliki persepsi tentang adanya hubungan hukum dalam transaksi terapetik. Persepsi responden tentang aspek hukum turunan dalam transaksi terapetik meliputi berlakunya hubungan kontraktual dalam transaksi terapeutik, sifat perikatan dalam transaksi terapeutik; serta hak dan kewajiban dokter dan pasien dalam hubungan kontraktual dalam transaksi terapeutik memiliki korelasi dengan latar belakang tingkat pendidikan responden.
PELAKSANAAN PATIENT SAFETY DALAM PROGRAM CORPORATE SOCIAL RESPONSIBILITY MELALUI BAKTI SOSIAL DI RUMAH SAKIT PREMIER JATINEGARA
Authors: Gegen Gerardus , Wahyati Y Endang , Murni Tri Wahyu
Published: February 2018

Dalam memberikan Pelayanan kesehatan yang baik, bermutu, profesional, dan diterima pasien merupakan tujuan utama pelayanan rumah sakit, namun hal ini tidaklah mudah dilakukan mengingat pelayanan kesehatan merupakan suatu organisasi yang sangat komplek, dibutuhkan suatu pengelolaan yang baik sehingga dalam pelayanan pasien merasa terlayani dengan baik. Hal ini diatur dalam Peraturan Menteri kesehatan Nomor 1691/MENKES/PER/VII/2011 Tentang Keselamatan Pasien, dilain pihak Rumah Sakit yangg berbadan hukum PT berkewajiban melaksanakan CSR sebagai mana diatur dalam PP Nomor 47 tahun 2012 tentang tanggungjawab sosial perusahaan. Penelitian ini mengunakan metode penelitian deskritif, dengan metode pendektan yuridis sosiologis sedangkan data yang dikumpulkan adalah berupa data primer dan data sekunder yang diperoleh melalui studi lapangan dan studi empiris, pustaka adapun analisis data dilakukan secara kualitatif.Rumah Sakit Premier Jatinegara adalah rumah sakit swasta yang berbentuk Perseroan Terbatas melaksanakan ketentuan tentang Patient Safety dalam melakukan baksos dalam bentuk pelayanan kesehatan bagi pasien tidak mampu sebagi tanggung jawab sosial sesaui dengan ketentuan perundang-undangan antara lain UU Kesehatan, Rumah Sakit, Perseroan Terbatas dan Penanaman Modal, adapun bentuk pelaksanaan Patient Safety secara internal di lakukan melalui SK direktur tentang Patient Safety dan surat tugas pelaksanaan bakti sosial, adapun faktor-faktor yang mempengaruhi pelaksanannya antara lain: faktor yang mendukung, ketersediaan tenaga sesuai kebutuhan, visi dan misi, karena amanat Undang-Undang, Faktor yang menghambat keterbatasan dana sehinga pelaksanaan baksos hanya tindakan membutuhkan yang tidak terlalu besar, kemudian sponsor hanya diperoleh secara temporel.
Self-assembly of supermolecular species directed by hydrogen bonding and aromatic π–π stacking interactions
Authors: Li Xin-Hua , Jalbout Abraham F. , Xiang Wei Dong
Published: February 2018

A new Cu(II) trimers, [Cu3(dcp)2(H2O)8]. 4DMF, with the ligand 3,5-pyrazoledicarboxylic acid monohydrate (H3dcp) has been prepared by solvent method. Its solid-state structure has been characterized by elemental analysis, thermal analysis (TGA and DSC), and single crystal X-ray diffraction. X-ray crystallographic studies reveal that this complex has extended 1-D,2-D and 3-D supramolecular architectures directed by weak interactions (hydrogen bond and aromatic π-π stacking interaction) leading to a sandwich solid-state structure.
Cerimetric determination of simvastatin in pharmaceuticals based on redox and complex formation reactions
Authors: Basavaiah Kanakapura , Devi Okram Zenita
Published: February 2018

Two sensitive spectrophotometric methods are described for the determination of simvastatin (SMT) in bulk drug and in tablets. The methods are based on the oxidation of SMT by a measured excess of cerium (IV) in acid medium followed by determination of unreacted oxidant by two different reaction schemes. In one procedure (method A), the residual cerium (IV) is reacted with a fixed concentration of ferroin and the increase in absorbance is measured at 510 nm. The second approach (method B) involves the reduction of the unreacted cerium (IV) with a fixed quantity of iron (II), and the resulting iron (III) is complexed with thiocyanate and the absorbance measured at 470 nm. In both methods, the amount of cerium (IV) reacted corresponds to SMT concentration. The experimental conditions for both methods were optimized. In method A, the absorbance is found to increase linearly with SMT concentration (r = 0.9995) whereas in method B, the same decreased (r = -0.9943). The systems obey Beer’s law for 0.6-7.5 and 0.5-5.0 μg mL-1 for method A and method B, respectively.
A simple method for the spectrophotometric determination of cephalosporins in pharmaceuticals using variamine blue
Authors: Pasha Chand , Narayana Badiadka
Published: February 2018

A simple spectrophotometric method for the determination of cefotaxime, ceftriaxone, cefadroxil and cephalexin with variamine blue is presented. The determination is based on the hydrolysis of β-lactam ring of cephalosporins with sodium hydroxide which subsequently reacts with iodate to liberate iodine in acidic medium. The liberated iodine oxidizes variamine blue to violet colored species of maximum absorption at 556 nm. The absorbance is measured within the pH range of 4.0-4.2. Beer’s law is obeyed in the range of 0.5-5.8 μg mL–1, 0.2-7.0 μg mL–1, 0.2-5.0 μg mL–1 and 0.5-8.5 μg mL–1 for cefotaxime, ceftriaxone, cefadroxil and cephalexin respectively. The analytical parameters were optimized and the method is successfully applied for the determination of cefotaxime, ceftriaxone, cefadroxil and cephalexin in pharmaceuticals.
Morphological and thermal analyses of flexible polyurethane foams containing commercial calcium carbonate
Authors: Sant'Anna Sabrina Sá , De Souza Denilson Arlindo , Carvalho Cornélio de Freitas , Yoshida Maria Irene
Published: February 2018

One filler often utilized in flexible polyurethane foams is calcium carbonate (CaCO3) because it is non-abrasiveness, non-toxicity and facilitated pigmentation. However, it is observed that the excess of commercial CaCO3 utilized in industry possibly causing permanent deformations and damaging the quality of the final product. The effect of different concentrations of commercial CaCO3, in flexible foams, was studied. Different concentrations of CaCO3 were used for the synthesis of flexible polyurethane foams, which were submitted to morphological and thermal analyses to verify the alterations provoked by the progressive introduction of this filler.
Flow injection analysis of vancomycin
Authors: Vila Marta Maria Duarte Carvalho , Salomão Acacia Adriana , Tubino Matthieu
Published: February 2018

A flow injection method for the quantitative analysis of vancomycin hydrochloride, C66H75Cl2N9O24.HCl (HVCM), based on the reaction with copper (II) ions, is presented. HVCM forms a lilac-blue complex with copper ions at pH≅4.5 in aqueous solutions, with maximum absorption at 555 nm. The detection limit was estimated to be about 8.5×10-5 mol L-1; the quantitation limit is about 2.5×10-4 mol L-1 and about 30 determinations can be performed in an hour. The accuracy of the method was tested through recovery procedures in presence of four different excipients, in the proportion 1:1 w/w. The results were compared with those obtained with the batch spectrophotometric and with the HPLC methods. Statistical comparison was done using the Student’s procedure. Complete agreement was found at a 0.95 significance level between the proposed flow injection and the batch spectrophotometric methods, which present similar precision (RSD: 2.1 % vs. 1.9%).