bluuebunny/crossref_metadata_2025 huggingface dataset:
SISTEMA DE INFORMAÇÃO GEOGRÁFICA E INDICADORES DESEMPENHO DA ATIVIDADE BOMBEIRO MILITAR NO TERRITÓRIO MARANHENSE
Authors: França Carlos David Veiga , Rodrigues Zulimar Marita Ribeiro , Cruz Rodrigo Fábio Martins
Published: June 2024

A carência de indicadores para avaliação de desempenho da atividade bombeiro militar no território maranhense é uma condição cultural que fomenta prejuízos à visibilidade e recebimento de recursos institucionais. Neste mote, a pesquisa propôs a aplicação do Sistema de Informação Geográfica como ferramenta para elaboração de indicadores chaves de performance para o Corpo de Bombeiro Militar do Maranhão. Os procedimentos metodológicos adotados perpassaram pelo tratamento dos dados secundários inerentes aos atendimentos realizados por essa instituição, no período de 2013 a 2020, em quatro municípios da Ilha do Maranhão. Foram analisadas as ocorrências e seus determinantes espaciais, estatísticas e produtos cartográfico, além de elaborar um banco de dados geográfico. Como resultados, observou-se o ano de 2019 com 9.745 registros; a capital maranhense com maior incidência de atendimentos (78,62%); as ocorrências de Atendimento Pré-hospitalar (24.794) são as mais incidentes; o turno da tarde como o de maior frequência de atendimentos e óbitos; 215 ocorrências resultantes em óbito; sendo a classe Busca e salvamento como a mais letal (57,21%). Identificou ainda a taxa de 496 ocorrências a cada 100 mil habitantes com média de atendimentos anuais de 7.746 casos predominantes para a capital maranhense. O uso do Sistema de Informação Geográfica demonstrou ser uma ferramenta viável de integração e análise espacial para elaboração de indicadores chaves de performance da atividade bombeiro militar na Ilha do Maranhão possibilitando a produção de uma cadeia de desempenho laboral.Palavras-chave: Indicadores chaves de performance. Ilha do Maranhão. Corpo de Bombeiros Militar. Sistema de Informação Geográfica.
A HABITAÇÃO NO CONTEXTO DAS LUTAS DOS TRABALHADORES URBANOS
Authors: Muniz Andreia Fernandes , Mendonça Eneida Maria Souza
Published: June 2024

Este artigo objetiva discutir sob a perspectiva histórica, a gênese da noção de moradia como “problema social” no Brasil, a partir da leitura dos fenômenos e processos que levaram a questão habitacional a ser debatida e enfrentada pelos trabalhadores urbanos alocados em diferentes categorias profissionais a partir da segunda metade do século XIX até 1930. Com ênfase nas mobilizações desses agentes sociais, a revisão crítica, construída sobre uma ampla base teórica, proporciona reflexões que se estruturam sob a lógica de evidenciar o poder coletivo da classe trabalhadora, fator mobilizador de lutas contra práticas de espoliação. Um poder coletivo baseado na articulação de um sujeito histórico, que no início do século XX se mobilizou por condições mais justas de moradia. O campo do trabalho evidenciou um problema histórico que permanece no país até os dias atuais.  Palavras-chave: Habitação. Trabalhadores urbanos. Lutas sociais.
CONSIDERAÇÕES SOBRE A PARTICIPAÇÃO POPULAR NO PLANEJAMENTO URBANO EM LONDRINA-PR
Authors: Battini Luciana de Mello
Published: June 2024

O Planejamento Urbano participativo e gestão democrática da cidade, respaldados no Estatuto da Cidade (Lei nº 10.257 de 10 de julho de 2001), buscam justiça social no espaço urbano. Os mecanismos para que a participação seja efetivada são diversos, alternando entre as metodologias da democracia representativa e da democracia participativa. Diversas discussões e análises podem ser levantadas a partir disso para mensurar se a participação é de fato popular ou favorecida para grupos com interesses antipopulares. A figura do Estado também é alvo de análise, uma vez que pode impulsionar ou negligenciar a participação. Portanto, esse artigo tem como objetivo buscar os significados da construção da essência participativa, a partir da discussão dos conceitos de democracia representativa e participativa e a aplicabilidade desse modelo previsto em lei no Plano Diretor Municipal do Município de Londrina-PR, como também analisar se a burocracia colocada pelo Estado conseguiu inserir a população de forma efetiva no Planejamento Urbano ou constituiu-se em uma mera formalidade perante a exigência da lei que continua a favorecer grupos hegemônicos. Dessa maneira, conseguimos pensar nos horizontes a se seguir levando em conta os obstáculos colocados pela democracia liberal e pelo modo de produção capitalista, traçando o objetivo de superá-los. Nos procedimentos metodológicos inicialmente foi feita a discussão e considerações sobre os conceitos de direito à cidade, democracia e participação; em seguida execução de trabalho de campo com participação em assembleias e oficinas preparatórias remotas nas etapas participativas das leis complementares colocadas em prática pelo Instituto de pesquisa e planejamento urbano de Londrina (IPPUL); e por fim, foi feita pesquisa no site do IPPUL para a coleta de dados sobre a participação popular.
 
Palavras-chave: Democracia participativa. Planejamento Urbano. Anticapitalismo. Direito à cidade.
A NETNOGRAFIA COMO METODOLOGIA DE INVESTIGAÇÃO EM GEOGRAFIA: um estudo para a compreensão da mobilidade urbana excludente e precária em Ribeirão Preto - SP
Authors: Abate Alexandre Antonio
Published: June 2024

O objetivo deste artigo é apresentar uma discussão metodológica sobre a Netnografia, a partir da nossa experiência de pesquisa no Mestrado Acadêmico em Geografia, além dos resultados provenientes da utilização dessa ferramenta metodológica para o estudo da mobilidade e da acessibilidade urbanas de citadinos que habitam o Conjunto Habitacional "Cristo Redentor", situado na periferia de Ribeirão Preto - SP. Dentre os resultados obtidos, destacamos que os problemas concernentes aos deslocamentos cotidianos estão presentes para todos os citadinos que se envolveram na investigação, independentemente do modal de deslocamento utilizado - automóvel, motocicleta ou transporte público. Além disso, a pesquisa revelou que há indicativos claros de problemas de mobilidade e de acessibilidade urbanas para a parcela dos citadinos residente nesse conjunto habitacional que necessita da utilização do transporte público, o que nos leva à ideia de mobilidade urbana excludente e precária.Palavras-chave: Netnografia. Mobilidade urbana. Acessibilidade urbana. Periferia. Ribeirão Preto.
Nilai Pendidikan Karakter Dalam Cerita Rakyat Jambi dan Relevansinya dengan Pembelajaran Bahasa Indonesia di SMP
Authors: Wahyuningsih Isti , Akhyaruddin Akhyaruddin , Setyonegoro Agus , Dewi Yusra , Purba Andiopenta
Published: June 2024

The purpose of this study was to describe the value of character education contained in Jambi folklore and its relevance to learning Indonesian in junior high schools. This research is in the form of qualitative descriptive. The data of this study is the value of character education in twelve Jambi folk tales and the data source is the bilingual Jambi Folklore book with twelve story titles, namely 1) Black Water and Clear Water, 2) Swearing Stone, 3) Buffalo Stone, 4) Likat Lake, 5) Datuk Blood Putih, 6) Datuk Kerungkung Bebulu, 7) Dideng Dang Ayu, 8) Girls with Long Hair, 9) Lubuk Bujang Girls, 10) Smooth People, 11) Rice as Big as a Coconut, 12) Tama Tujeuh. The findings from this study include: there are five aspects of character education proclaimed by the Ministry of Education and Culture, namely religious, nationalist, independent, mutual cooperation and integrity and Jambi folklore is relevant to learning Indonesian in junior high school because it can be used as teaching material.
Pengaruh Media Pembelajaran Berbasis QR Code terhadap Kemampuan Menulis Naskah Drama Siswa Kelas VIII SMP Negeri 14 Kota Jambi
Authors: Rachmahtika Rachmahtika , Kamarudin Kamarudin , Budiyono Herman , Purba Andiopenta , Akhyaruddin Akhyaruddin
Published: June 2024

This research aims to determine the effect of QR Code media on the ability to write drama scripts. This research is a quantitative type of research with a Nonequivalent Control Group pretest and posttest design. The population in this study were all students in class VIII of SMP Negeri 14 Jambi City. Sampling in this study used the Purposive Sampling technique, the sample used was 62 students who were divided into two classes, namely 31 students in class VIII C as the control class and 31 students in VIII E as the experimental class. Research data was obtained through interviews, documentation, and test instruments (Pretest and Posttest). The results showed that the average posttest score for the experimental class was 70.8 and the control class was 64.3. The results of the hypothesis test using the t test, show that the output results obtained a sig value. (2-tailed) is 0.018 < 0.05, so Ha is accepted and Ho is rejected, so there is a significant influence of QR Code media on students' ability to write drama scripts.
PENGARUH BERBAGAI KONSENTRASI DAN LAMA PERENDAMAN NaCl TERHADAP MUTU KRIPIK PARE (Momordica charantia)
Authors: Mirnadianti Mirnadianti , Sabahannur St. , HS Suriyanti
Published: June 2024

Mirnadianti (08220160015) Effect of Various Concentrations and Duration of Soaking NaCl on the Quality of Pare Chips (Momordica charantia). Supervised by Sabahannur and Suriyanti HS.This study aims to determine the effect of concentration and duration of soaking NaCl on the quality of bitter gourd chips using vacuum frying. The study was conducted at the Post-Harvest Technology Laboratory, Faculty of Agriculture, Universitas Muslim Indonesia, from March to April 2022. This study used a completely randomized design (CRD) with a two-factor factorial pattern. The first factor, is NaCl 2%, 4%, and 6%. The second factor is immersion, namely: 2 hours, 4 hours, and 6 hours. Parameters measured were: yield, moisture content, ash content, fat content, and Organoleptic Test on taste, color, and texture. The results of soaking bitter melon in 6% NaCl solution for 2 hours showed the highest yield of 33.05%, Immersion in 4% NaCl solution for 4 hours showed the lowest fat content of 44.38%. Soaking in 4% NaCl solution for 6 hours showed the lowest water content was 3.97%. Soaking in 2% NaCl solution for 4 hours produced the highest ash content with a value of 10.35%. The results of the organoleptic test with 4% NaCl and soaking for 6 hours produced the best taste for bitter melon chips, which was 70.71 (like).
PERCEPCIONES DE ESTUDIANTES CON DISCAPACIDAD RESPECTO A LOS DESAFÍOS EN EL AULA UNIVERSITARIA
Authors: MEJÍA CAJAMARCA Paulina , Ullauri Ullauri Jaime Iván
Published: June 2024

La participación de las personas con discapacidad en la universidad representa un gran desafío que implica potenciar cambios para promover la inclusión. Por ello, el objetivo de esta investigación fue conocer las perspectivas de los estudiantes universitarios con discapacidad sobre las barreras de aprendizaje y desafíos que estas generan en desarrollo de una participación inclusiva educativa en la carrera de Educación Básica de la Universidad Nacional de Educación. El enfoque metodológico utilizado fue cualitativo, las percepciones captadas se analizaron por temáticas relacionadas a los desafíos que experimentan los estudiantes con discapacidad en la universidad, posterior a ello dicho análisis se apoyó en la estadística descriptiva.  Los resultados y conclusiones han permitido explorar la experiencia de los estudiantes con discapacidad en el contexto formativo universitario, marcada por desafíos significativos como dificultades de acceso a recursos educativos adaptados, obstáculos en la interacción en el aula, barreras sociales y emocionales generadas por la incomodidad en la interacción con compañeros y profesores debido a la falta de comprensión de las discapacidades, aspectos que afectan al desempeño académico y emocional de los estudiantes con discapacidad. Asimismo, se identificó como la autopercepción negativa incide en el desarrollo emocional armónico del estudiante con discapacidad. Concluyendo que la ruta hacia la corresponsabilidad y formación de los actores educativos debe favorecer la inclusión de los estudiantes con discapacidad en la universidad.
Formación laboral y articulación con el mundo del trabajo: un desafío para seguir repensando las prácticas educativas en Córdoba, Argentina
Authors: Rubiolo Paula
Published: June 2024

En este artículo se abordan los apoyos vinculados con la formación laboral, en términos de acciones de las políticas educativas para planificar, articular y sostener espacios de inclusión laboral posteriores al egreso de la educación obligatoria. Los datos provienen de una investigación doctoral cuyo objetivo consiste en analizar apoyos escolares en el nivel secundario y postescolares vinculados a los procesos de transición a la vida adulta de jóvenes con discapacidad en Córdoba, Argentina.
Los antecedentes otorgan un papel fundamental a la escuela en la construcción de puentes para la inclusión social y laboral, así como también destacan la importancia de acciones formativas y de orientación para el ejercicio de roles propios de la adultez como la incorporación al mercado de trabajo, mediante una planificación multidimensional y coordinada que, desde un enfoque de derechos, posibilite el acceso a los apoyos necesarios para alcanzarlo.
El diseño de investigación se enmarca en un estudio de casos múltiples con enfoque cualitativo y alcance descriptivo, los casos seleccionados corresponden a 4 escuelas públicas de modalidad especial de la provincia de Córdoba. Se indagó a actores claves para el análisis del problema profundizando en los significados de los procesos formativos y su vinculación con experiencias posteriores de inserción al mercado laboral.
Entre los principales resultados se destaca una mirada unidireccional sobre la vida adulta-trabajo, asociada fundamentalmente a oficios y actividades manuales, como un destino prácticamente único para las personas con discapacidad y reafirma la necesidad de una revisión crítica de los sentidos que sustentan las prácticas educativas, pensadas casi exclusivamente al interior de las instituciones.
Se espera contribuir al debate sobre el rol que las escuelas ejercen en la formación para la inclusión en el mercado laboral, interpelando prácticas segregacionistas que reproducen la histórica desventaja social en que se ubica a las personas con discapacidad.
Diseño para la elaboración los Planes de Apoyos Personales en el ámbito de la discapacidad intelectual
Authors: Carbó Carreté Maria , Font Roura Josep , Balcells Balcells Anna
Published: June 2024

En los últimos años, se han llevado a cabo numerosas investigaciones dirigidas a personas con discapacidad intelectual, con el objetivo principal de desarrollar instrumentos de medida válidos y fiables para evaluar tanto las necesidades de apoyo de las personas con DI como su la calidad de vida. Sin embargo, el impacto de estos trabajos en las personas con discapacidad intelectual es cuestionable.
En este contexto, el presente estudio, tiene como objetivo principal proporcionar a las entidades los recursos y conocimientos derivados de la investigación, para que los integren en sus procedimientos de los Planes de Apoyo Personal. Este trabajo ha sido posible gracias a la colaboración activa de cinco entidades de servicios a personas con discapacidad intelectual en Cataluña.
El resultado concreto de este esfuerzo conjunto ha sido la elaboración de guías basadas en las contribuciones más recientes de la investigación. Estas guías han sido revisadas y consensuadas por los profesionales de las entidades y el equipo de investigación, asegurando así la calidad y pertinencia de las recomendaciones ofrecidas. Estas guías pretenden ser una herramienta valiosa para las entidades en la elaboración de sus procedimientos y, en última instancia, mejorar la calidad de vida de las personas con discapacidad intelectual y sus familias.
Development of domestic meso-economy: Theory and practice
Authors: Nikonova Alla A.
Published: June 2024

The article outlines the main content of the participants’ reports at the presentation of the monograph “System-oriented modelling of the real sector of the Russian meso-economy”, prepared by scientific researchers of the Central Economics and Mathematics Institute of the Russian Academy of Sciences (CEMI RAS). The monograph presents the study results of the current problems in the development of the domestic meso-economy using the methods of economic and mathematical modelling and system analysis.
The impact of the sale of Russian divisions of western companies on the technological level of production in Russia
Authors: Gurkov Igor B. , Filinov Nikolay B. , Saidov Zokirzhon B.
Published: June 2024

The article provides a general overview of the development of the reaction of companies from “unfriendly countries” with manufacturing subsidiaries in Russia to the development of the Russian-Ukrainian crisis, empirical studies of the phenomenon and attempts to theoretically understand it. The purpose of the work is to stage the process and identify constructs from the theory of international business and related academic fields that could be and was used to explain and predict the behavior of its participants. The work is based on the authors’ database of all 280 enterprises of Western corporations opened in Russia between January 2012 and December 2019. The current version of the database includes profit and loss statements of 280 companies from 2019 to 2022, as well as information on their sales in 2022. The first stage of the reaction of Western business (2014 – ​February 2022) was a market restructuring and included both the departure of some companies from the Russian market and the opening of new production facilities from existing market players and the arrival of new ones. The second stage (February 2022 – ​end of 2022) was characterized by a relatively free exit of Western companies from the Russian market, which took various forms. In general, 27.8% of production facilities created in 2012–2019 by Western companies changed owners, varying by industry from 20 to 40%. It is too early to judge the impact of this departure on the economy in terms of production volumes, its technological level and management culture: there is no data. If we evaluate the scope of this exit in the value of fixed assets, that have changed owners, tht figure amounted to 1–2% of the cost of fixed assets in the corresponding sector of Russian industry, and only in the industry “Metallic works” it amounted to 5.7%. The third stage, which continues in present, is characterized by the introduction by the Russian side of significant restrictions that complicate and slow down divestment and prevent the disintegration of production complexes created by Western investors with the sale of equipment and the elimination of jobs.
Supply-Chain Antitrust and Being Too Big in the Context of AT&T’s 1984 Breakup
Authors: Dalkir İsmail Serdar , Kalkan Ekrem
Published: June 2024

In 1984, due to a US Department of Justice antitrust lawsuit, AT&T, the U.S. telecommunications monopoly, split into eight entities, including long-distance and local service providers known as Regional Bell Operating Companies (RBOCs). Vertical integration of suppliers typically benefits consumers by avoiding the issues associated with successive monopolies, where prices may be excessively high. The separation of long-distance and local services by the Department of Justice may seem counterintuitive, potentially driven by concerns over AT&T's size rather than economic rationale. This paper suggests that integrated monopolies have more willingness to build demand rigidity due to an absence of the free-riding problem, leading to higher prices. The implications extend to regulated firms and social media, highlighting the complexity of antitrust actions and their economic consequences on market dynamics and consumer welfare.
Clinical and Etiological Profiles of Anemias in the Internal Medicine Department of Kara Teaching Hospital
Authors: Lihanimpo Djalogue , E dem Mossi Komi , Toyi Tchamdja , Agbeko Djagadou Kodjo , Abago Balaka , Awalou Djibril Mohaman
Published: June 2024

Objective: The aim of this study was to describe the clinical and etiological profile of cases of anemia treated in the internal medicine department of Kara University Hospital. Method: This was a retrospective study carried out over 3 years, from April 2020 to May 2023, which focused on patients admitted to the internal medicine department of Kara University Hospital for clinical and/or biological anemia. Results: A total of 74 cases of anemia were identified during the study period out of a total of 2840 files examined, representing a frequency of 2.61%. The average age of patients with anemia was 45.12 years ± 16.91 with extremes ranging from 18 to 80 years and the M/F sex ratio was 0.76. Clinical signs were variable, dominated by asthenia, tachycardia, pallor and dizziness. The average hemoglobin level was 6.15 g/dl, with extremes of 2 and 11.50 g/dl. The anemia was normocytic in 51.4% of cases and severe in 52.70% of cases. The etiologies were varied, dominated by snakebite envenomations (32.43% of cases) and severe anemic malaria (24.32% of cases). Conclusion: Anemia is a frequent reason for consultation/hospitalization in internal medicine at Kara University Hospital. It represents a real diagnostic challenge for the internist, sometimes in an emergency context. It is essential to research the etiology for better management.
Intergenerational Knowledge of Ageism and Attitudes towards Age Stereotypes
Authors: Brina Felc , Zlata Felc
Published: June 2024

Not much is known about the knowledge of ageism and the attitude towards ageist stereotypes among adolescents, adults and the elderly, so we tried to find out both in the survey. Methods: This voluntary two-part online survey among 384 participants aged 15 to 90 from Eastern Slovenia determined intergenerational knowledge of ageism and attitudes towards age stereotypes. Three different age groups consisted of 188 adolescent students in 2022, 47 adults and 139 elderly in 2023. An important part of the questionnaire was formed by 31 stereotypical statements about the elderly on a three-point Likert scale, divided into six categories: (I) mood, (II) traditionalism, (III) frailty, (IV) attitude towards technology, (V) wisdom and (VI) sociability. Results: It turned out that the knowledge of ageism and the attitude towards age stereotypes depend most on the age of the respondents. Only 18.6% of adolescents knew ageism, only those with an older relative and 49.5 % of adults and elderly were familiar with ageism. The latter defined it like this: 41.9% as interpersonal ageism, 14.5% as self-directed ageism, and 4.8% as institutional ageism. Furthermore, 29.6 % of adults and older respondents have experienced it as interpersonal ageism, mostly (50%) it was experienced by children, youth and other people, slightly less (27.5 %) experienced it as interpersonal ageism from random passers. A minority (7.5 %) of adult and elderly respondents also described that they experienced it from the side of the closest ones, and 7.5% as institutional ageism. Representatives of all three different age groups had a mixture of positive, neutral and negative attitudes towards stereotypes about the elderly. The biggest differences between generations were regarding the perception of traditionalism of elderly (p=0.002), the opinion of the attitude of the elderly towards technology (p=0.028) and the opinion of sociability of older people (p<0.001). The opinion of traditionalism was most negative among adolescents, and then improved with advanced age of respondents. Regarding the attitude towards modern technology, the most negative opinion existed among younger adolescents (15-17 years old) and adults (20-64 years old), while the opinion of older adolescents (18-19 years old) and those aged 65 and over was more positive. Regarding the sociability of the elderly, positive opinions of both groups of adolescents stood out the most, and then declined with advanced age of respondents. The differences between the positive view of the generations on the wisdom of the elders were insignificant. Conclusion: The concept of ageism is more familiar among adults and the elderly than among adolescents. The negative and positive attitudes towards age stereotypes are intertwined from adolescence onwards although in adolescence, the attitude towards the elderly is most inclined to negative attitudes, which can strengthen the mechanisms of negative ageism already in early youth.
Addressing Obesity in the Oceanic Population: Challenges, Solutions, and Pathways to Health
Authors: Barnett Thomas E
Published: June 2024

This study is a triphasic exploration of the Oceania region’s disproportionate obesity rates and access to obesity related clinical trials. To accomplish this, this study investigated the prevalence of obesity clinical trials compared to the worldwide population proportion, the validation of existing obesity data for this population, and the application of exercise and non-exercise-based clinical trials. No statistically significant relationship was noted between the regional population and obesity clinical trial proportions. Simply, the size of a regional population did not directly influence the number of clinical trials. However, findings did validate that Oceanic populations exhibit higher Body Mass Index (BMI) values compared to the global population, in alignment with previous literature. One sample t-tests revealed a statistically significant difference (p <.001) difference between mean BMI, obesity rate (BMI >30), and morbid obesity rate (BMI >40) in Oceanic populations compared to worldwide rates. Despite the disproportionate obesity rates in this demographic, a negligible number of clinical trials, especially those including exercise interventions, have been made available to this population. Finally, exercise-based clinical trials were used infrequently worldwide, a rate that was exceptionally low amongst studies conducted in the Oceania region. Of note, emerging literature suggests that Oceanic populations, specifically Polynesians, exhibit a genetic anomaly that increases body mass without necessarily increasing fat mass via allele rs373863828. Thus, while the existing BMI data expresses significantly higher obesity rates, more comprehensive research is needed on this population to understand this demographic’s typical body composition. Otherwise, some areas within the Oceania region continue to exhibit obesity rates exceeding five times that of the world average, yet are rarely provided with obesity clinical trials to mitigate obesity-related disease and comorbidities. These findings suggest a need for more equitable allocation of research resources to address the unique challenges posed by obesity in the Oceanic population.
Dopaminergic Drugs to Relieve Pain from Chronic Pancreatitis- A Novel Therapy
Authors: Check Jerome H , Neumann Brooke , Check Diane L
Published: June 2024

Purpose: To describe a highly effective novel treatment for relieving pain from chronic pancreatitis even when high potency long-acting opioids fail to improve pain. Methods: Dextroamphetamine sulfate slowly titrated to achieve the closure to a tolerable dosage that relieved severe abdominal pain was given to a 50-year-old male suffering from chronic pancreatitis that failed to respond to all medical therapies including high potency opioids. Results: After one year with marked improvement of severe abdominal pain, at a dosage of 90 mg amphetamine salts (56.4 ng dextroamphetamine sulfate), he was almost pain free with only occasional use of amphetamines. Most importantly he was completely off all other medication for pain including his high dosage opioids. Conclusion: Though dextroamphetamine sulfate has been reported to ameliorate various types of abdominal pain, and pain in other areas of the body, even when standard therapies fail, this is the first reported case of marked abrogation of pain from chronic pancreatitis. The hypothesized medicine is that dextroamphetamine release dopamine from sympathetic nerve fibers, which in turn diminishes cellular permeability, and thus inhibits absorption of irritants into pancreatic tissue causing inflammation and pain.
Childhood Experiences with Disabilities, Hemisphere Dominance and Use of Internet Forums in Those Affected with Body Integrity Dysphoria
Authors: Becker Diana , Kasten Erich
Published: June 2024

Body Integrity Dysphoria (BID), previously also known as Body Identity Integrity Disorder (BIID), is a disorder in which those affected do not perceive body parts as belonging to them and often seek amputation. Aim: The present study addresses the following questions: Do those affected by BID have frequent memories of contact with amputees in childhood or adolescence? Is hemispheric dominance related to the side of the need for amputation? How many affected people use Internet forums to exchange ideas with other affected people? Method: 44 people affected by BID were examined. This group was compared with a parallel sample of non-affected people in terms of age and gender. Results: The proportion of homosexuals and bisexuals in the BID group is significantly higher than in the control group. The BID group has significantly more divorced parents and significantly more amputees in their social environment, but - contrary to the hypothesis - fewer amputees among their parents in childhood and adolescence. 98% of those affected use special BID forums on the Internet. A connection between right- or left-handedness and the need for amputation on the right or left side was not found. Six patients had attempted amputation themselves. Conclusions: The data do not suggest that the need for disability was modelled in childhood.
Cocaine-Induced Stroke in A Young Patient
Authors: Mnaili Mohamed Amine , Bourazza Ahmed
Published: June 2024

Cocaine consumption has increased over the last decade. The potent sympathomimetic effects of the drug can lead to serious neurovascular complications in the form of ischemic stroke (IS), intracerebral hemorrhage (ICH), or subarachnoid hemorrhage (SAH). A young adult patient arrived at a specialized unit with neurological deficits and a history of acute and long-term illicit drug use and presented no other comorbidities. In addition, he presented laboratory and serological tests without alterations. The only risk factor identified for stroke was, therefore, cocaine use.
Effectiveness of COVID Counseling Provided By Health Care Providers in the Primary Healthcare COVID-19 Assessment Centers in Dubai
Authors: Prasad Sajitha , Sharma Sangeeta , Hussain Nazneen , Bashir Amal Mahgoub , Prasad Pranav S , Maqbool Adil
Published: June 2024

Background: The COVID-19 pandemic has highlighted the critical role of effective communication in healthcare, especially in primary care settings. This study focuses on evaluating the effectiveness of COVID-19 counseling provided by healthcare providers in primary healthcare centers in Dubai. Methods: A cross-sectional, prospective observational study was conducted over a period of three months, encompassing a diverse sample of 100 patients who had experienced COVID-19. Data were collected through telephone interviews, online surveys and on-site questionnaires, focusing on patients' awareness of COVID-19 protocols and their satisfaction with the counseling received. Results: The findings revealed a high level of patient awareness regarding testing frequency, symptoms and self- isolation protocols. A significant proportion of patients [81%] reported satisfaction with the counseling received. However, gaps were identified in communication regarding the proper disposal of masks and gloves and disinfection practices at home. An association was found between vaccination status and the type of information received. Conclusion: The study demonstrates the effectiveness of COVID-19 counseling in Dubai's primary healthcare centers, underscoring the importance of comprehensive communication strategies in healthcare settings.
A Novel Effective Therapy for Chronic Generalized Pruritus without Presence of Skin Lesions
Authors: Grace Lombardi , Jerome Check H
Published: June 2024

Rationale: There is evidence that the etiology of many skin disorders with or without obvious lesions may be secondary to excessive infiltration of irritants into the dermis causing inflammation. There is evidence that taking medications that release more dopamine from sympathetic nerve fibers may prove highly effective for treating a larger variety of skin disorders despite resistance to standard therapy. Data support the concept that dopamine acts to diminish cellular permeability thus inhibiting infiltration of excessive irritants. Objective: to determine if dextroamphetamine, a dopaminergic drug, could relieve generalized pruritus' without skin lesions in a 30-year-old woman with 1 1⁄2 years of pruritus. Findings: The pruritus had moderately relieved shortly after treatment with 20mg amphetamine salts 11.6 mg dextroamphetamine sulfate (20mg amphetamine salts) and was completely eradicated with 23.2mg (40 mg amphetamine salts. In addition to the drug relieving her pruritus, she had a marked reduction in her fibromyalgia and dysmenorrhea and this probably helped to correct her infertility problems. Conclusions: A literature search found only one previous case of improvement of generalized idiopathic pruritus but with treatment of dextroamphetamine in a menopausal woman. Her pruritus was ascribed possibly to dry skin related to menopause related to estrogen deficiency. Thus, this is only the second case of successful treatment of idiopathic generalized pruritus without skin lesions with dextroamphetamine sulfate, but the first one in a younger woman.
An Improved Quantitative Optional Randomised Response Technique with Additive Scrambling using Two Questions Approach
Authors: Tiwari Neeraj , Pandey Tanuj Kumar
Published: June 2024

In this paper, an improved two-stage and three-stage optional randomized response (ORR) models for quantitative variables that make the use of additive scrambling was proposed. These two-stage and three-stage models achieve efficient estimation of the mean and sensitivity level simultaneously in the single sample by using two questions. It is found that the proposed models perform better than the existing ORR models in terms of estimating sensitive attribute and sensitivity level simultaneously. It is found that the proposed three stage ORR model provides better estimates than the two-stage and one-stage ORR models and offers more privacy to the respondents with suitable choice of design parameters. The properties of the proposed models are demonstrated with the help of a numerical study.
Global change across the early Eocene and its warming events
Authors:   , Fokkema Chris Daniël
Published: June 2024

Under present-day anthropogenic climate change, the extent of future warming and its global distribution have become pressing scientific concerns. Crucial information for addressing these unknowns is captured within the geological record, offering a window into ancient climates under vastly different or fluctuating CO2 concentrations.

This work delves into the 'hothouse' conditions of the early Eocene (56–48 million years ago). This time was characterized by surface temperatures 10–14 °C higher than today and CO2 concentrations approximately three to five times higher than present, and ice sheets were presumably absent. During this period, many repetitive warming events (hyperthermals) occurred, driven by variations in Earth's orbit. Our knowledge of these hyperthermals was primarily limited to a few records of changing ocean bottom water conditions. Yet, these phases offer a great opportunity to study the effects of global warming.

In this work, early Eocene climate was reconstructed using sediment cores retrieved at three locations from tropics to poles: the equatorial Atlantic, the northern Negev, and the Arctic Ocean. The variability of surface ocean temperatures was reconstructed at these sites using temperature-sensitive molecular fossils, derived from marine archaea. Surface ocean conditions were further evaluated by analyzing assemblages of fossil organic walled dinoflagellate cysts.

A main result of this work is that a surface warming signal was observed during multiple hyperthermals and smaller orbital variations at all sites, confirming their global nature. During these variations, the polar regions experienced approximately twice the warming of the tropics, due to the effect of 'polar amplification'. In the absence of polar (sea)ice, this gives an interesting insight in the non-ice-related drivers of present-day polar amplification.
Furthermore, the impact of the hyperthermals on tropical ocean surface ecosystems was investigated. Interestingly, no systematic biotic response was recorded during the smaller hyperthermals (below ~1.5 ºC surface warming). These finding contrasts previous work which documented significant biotic disruption during the larger hyperthermals and suggests a warming threshold for ocean surface biotic response.
Finally, the effects of the warming intervals on the hydrological cycle were explored as well. These findings, amongst others, indicate that subtropical regions became drier during hyperthermals, while polar areas experienced wetter conditions.

In summary, this work presents new insights in the distribution and effects of warming on orbital scale during the early Eocene hothouse world.
Competitive Sports Anxiety, Healing Imagery and Achievement Goal; Mediating Role of Coaching Feedback in Young Pakistani Athletes
Authors: Ali Yumna , Farhana Kazmib Syeda
Published: June 2024

Background. Sports psychology is integral to be taught both in academic settings and on practical athletic fields. This study considers students who are part of the physical education and sports department, whose responsibilities are twofold. Practical implications of managing sports anxiety, recovering from the ordeal of rehabilitation injuries, and achieving sports goals are crucial aspects of coaching feedback.
Aim: to explore competitive sports anxiety among enrolled student-athletes, the role of healing imagery in athletic injury recovery, and the achievement goals in the sports of cricket, hockey, and squash, with the mediation of coaching feedback.
Methods: Purposive sampling was utilized to investigate 58 athletes on the psychological constructs of Competitive Sports Anxiety (Cox et al., 2003), Healing Imagery in Athletic Injury Scale (Cressman, 2010), Achievement Goal in Sports (Sean et al., 2008), and Coaching Feedback (Stein, 2009) across three prevalent sports: cricket, hockey, and squash in the region.
Results Moderate, significant correlations are observed among the variables. There is a highly significant and positive impact of healing imagery on athletes’ achievement goals, both in terms of ego and mastery. Coaching characterized by positivity and punishment orientation significantly affects goal achievement. Healing imagery serves as a partial mediator between competitive sports anxiety and athletes' achievement goals.
Conclusion. Competitive sports anxiety can hinder the effectiveness of healing imagery and steer athletes away from achieving their goals. When athletes have mastered their sport, they are less inclined to utilize healing visualization techniques. As a result, coaches must adapt their teaching strategies to cater to the individual needs of athletes. Providing sports students and active players with regular sports psychological workshops and access to the latest therapies is essential. Exploring the motivational climate is integral for future studies.
Keywords: competition, sports anxiety, healing imagery, achievement goal, coaching feedback
Advances of Immune Cells in the Pathogenesis and Targeted Therapy of Systemic Lupus Erythematosus
Authors: Fang Junyue , Lin Li , Xiao Xiaoyun , Tian Jingwei , Zhang Meng , Saw Phei Er
Published: June 2024

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease reflecting an imbalance between regulatory and effector immune responses. With the rapid development of molecular biology and multi-omics, the pathogenesis of SLE has been gradually elucidated. In particular, imbalances and abnormalities in immune cell function have been shown to play an important role in the development of SLE. Understanding the specific pathogenesis of SLE is the basis for targeted therapy against specific targets. In this review, we describe the latest research progress on the involvement of immune cells in the pathogenesis of SLE and the potential of targeting different immune cells for therapeutic purposes. Then the importance of precision medicine for SLE disease management is also discussed. Finally, we emphasize recent advances in nanoparticle (NPs)-mediated drug delivery systems for targeted therapy of SLE.
A religião e a incidência dos meios eletrônicos na Comunidade Cristã Paz e Vida em tempos de Covid-19
Authors: Coelho André Magalhães
Published: June 2024

Este artigo é resultado de uma etnografia feita na Comunidade Cristã Paz e Vida, de São Mateus, na periferia da Zona Leste de São Paulo em épocas de Covid-19. O objetivo é mostrar a incidência dos meios eletrônicos, assim como o espaço virtual utilizado pela instituição religiosa, no contexto pandêmico. O estudo aborda em que medida o religioso participou da vida comunitária da igreja com o uso dessas ferramentas para a manutenção dos rituais e cultos. O material empírico coletado para esta pesquisa é formado por um pastor chamado de B, dois fiéis da igreja, denominados de membros A e C, e dois obreiros, apresentados como B e C. A pesquisa desenvolveu-se com base em observação de campo, através da verificação do comportamento dos fiéis, e sua interação em mídias sociais como o WhatsApp.
Relações, sensibilidades e conflitos na escola: interfaces no trabalho do coordenador pedagógico
Authors: Silva Jeanny Meiry Sombra , Almeida Laurinda Ramalho
Published: June 2024

Este texto é um recorte de uma pesquisa, cujo objetivo principal foi compreender de que forma as relações interpessoais existentes na escola interferem nas práticas profissionais de coordenadores pedagógicos, influenciando seus processos formativos. Em nosso estudo, foram aplicados quarenta e três questionários a professores de três escolas públicas da rede estadual de São Paulo. Apoiamos nosso percurso teórico em dois estudiosos, Wallon (1971, 1975, 1986, 1995), nos conceitos de meios e grupos, e Libâneo (2013), para entender a influência do meio escolar na dinâmica das relações. Os resultados do estudo evidenciaram que o estilo de gestão adotado na escola influencia as interações entre as pessoas, balizando formas de relacionamento e as mais variadas práticas.
As ligações internacionais na aglomeração urbana transfronteiriça do Iguaçu
Authors: Leitzke Airton
Published: June 2024

As intensas relações entre as cidades da aglomeração urbana transfronteiriça do Iguaçu (AUTI) são estabelecidas, principalmente, a partir do comércio de produtos importados, do turismo e, mais recentemente, da ampliação das atividades das Instituições de Ensino Superior (IES). Este artigo tem o objetivo de analisar a mobilidade transfronteira e as ligações internacionais estabelecidas entre as cidades dessa região, principalmente entre Foz do Iguaçu (PR) e Ciudad del Este (PY), buscando entender como o aumento da oferta de serviços nesse nível de ensino tem reconfigurado tais ligações. Para tanto, foram consideradas informações sobre os cursos de Medicina em IES particulares, presentes nas duas cidades e seus estudantes, assim como dados acerca da mobilidade transfronteiriça. A partir dos resultados alcançados neste texto, pode-se inferir que a oferta de cursos superiores, principalmente os de Medicina, é um elemento cada vez mais importante nesse contexto.
25 anos do Núcleo de Pesquisa, Documentação e Referência sobre Movimentos Sociais e Políticas Públicas no Campo (NMSPP) e suas contribuições para iniciativas de justiça de transição
Authors: Brito Ricardo Braga , Bastos Gabriel Souza , Oliveira Luíza Antunes Dantas de , Teló Fabrício
Published: June 2024

Neste trabalho, refletimos sobre os 25 anos do Núcleo de Pesquisa, Documentação e Referência sobre Movimentos Sociais e Políticas Públicas no Campo (NMSPP), analisando suas contribuições para a justiça de transição no Brasil. Quando da criação das comissões da verdade, entre 2012 e 2013, o NMSPP já possuía conjunto significativo de documentos sobre as lutas camponesas, indígenas e as violações de seus direitos, deflagradas durante a ditadura empresarial-militar de 1964-1985. Tal acúmulo permitiu que pesquisadores/as do NMSPP atuassem junto à Comissão Camponesa da Verdade e Comissão Estadual da Verdade do Rio de Janeiro, seguidas de projetos de extensão e pedidos de reparação, experiências aqui relatadas e analisadas. Devido às especificidades da repressão no campo, tais investigações ajudaram a dar centralidade a um conjunto de violações que vão além das categorias incorporadas pelo direito internacional, que muitas vezes limitam as iniciativas da justiça transicional a um conjunto restrito de violações.
O Brasil pós-Comissões da Verdade: reflexões 60 anos depois do golpe de 1964
Authors: Sanglard Fernanda Nalon , Camisasca Marina Mesquita
Published: June 2024

Este artigo parte do argumento de que a implantação de comissões da verdade no Brasil foi o estopim para uma virada conservadora que tomaria proporções inimagináveis na ocasião da criação de tais comissões. Sessenta anos após o golpe de 1964, partindo de uma análise historiográfica, sociológica e comunicacional, o texto discute o impacto e o legado das comissões da verdade no Brasil, assim como a ascensão de uma perspectiva autoritária após a divulgação dos relatórios finais das principais comissões. Pretende-se avaliar o papel desempenhado pelas comissões de forma articulada com a Comissão Nacional da Verdade (CNV), compreender tal virada conservadora a partir das políticas de direitos humanos e articular essas reflexões ao debate acadêmico acerca da memória, da censura e da liberdade de expressão no Brasil.
Rare but diverse off-target and somatic mutations found in field and greenhouse grown trees expressing CRISPR/Cas9
Authors: Goralogia Greg S. , Andreatta Isabella M. , Conrad Victoria , Xiong Qin , Vining Kelly J. , Strauss Steven H.
Published: June 2024

Introduction: CRISPR gene editing, while highly efficient in creating desired mutations, also has the potential to cause off-target mutations. This risk is especially high in clonally propagated plants, where editing reagents may remain in the genome for long periods of time or in perpetuity. We studied a diverse population of Populus and Eucalyptus trees that had CRISPR/Cas9-containing transgenes that targeted one or two types of floral development genes, homologs of LEAFY and AGAMOUS.

Methods: Using a targeted sequence approach, we studied approximately 20,000 genomic sites with degenerate sequence homology of up to five base pairs relative to guide RNA (gRNA) target sites. We analyzed those sites in 96 individual tree samples that represented 37 independent insertion events containing one or multiples of six unique gRNAs.

Results: We found low rates of off-target mutations, with rates of 1.2 × 10−9 in poplar and 3.1 × 10−10 in eucalypts, respectively, comparable to that expected due to sexual reproduction. The rates of mutation were highly idiosyncratic among sites and not predicted by sequence similarity to the target sites; a subset of two gRNAs showed off-target editing of four unique genomic sites with up to five mismatches relative to the true target sites, reaching fixation in some gene insertion events and clonal ramets. The location of off-target mutations relative to the PAM site were essentially identical to that seen with on-target CRISPR mutations.

Discussion: The low rates observed support many other studies in plants that suggest that the rates of off-target mutagenesis from CRISPR/Cas9 transgenes are negligible; our study extends this conclusion to trees and other long-lived plants where CRISPR/Cas9 transgenes were present in the genome for approximately four years.