bluuebunny/crossref_metadata_2025 huggingface dataset:
Settler Colonialism, Sport, and Recreation
Authors: Laurendeau Jason
Published: September 2024

Laurendeau interrogates the interconnections between settler colonialism and sport, recreation and physical activity, theorizing sport as both a site of ongoing colonial violence and a vital space of resistance, refusal, and reterritorialization. Laurendeau explains that settler colonialism is not a relic of a past moment but an ongoing genocidal project in still settling states as they perpetually work to claim ownership of and authority over stolen lands as part of a project of capital accumulation. Moreover, Laurendeau highlights, settler colonialism is a project that is fundamentally relational, structuring the lives not only of Indigenous peoples but of all who live in occupied territories. Sport and recreation, Laurendeau explains, constitute a key cultural space that produces and/or challenges ideas about bodies, relationships, belonging, nationhood, sovereignty, and more. Drawing primarily but not exclusively on examples unfolding on lands claimed by Canada, Laurendeau describes how sports like lacrosse and hockey, mega-events such as the North American Indigenous Games, and institutions and practices like sport in residential schools illustrate both the violences of settler colonialism and the refusals of those violences. Laurendeau takes an explicitly politicized approach to this work, highlighting the need to dismantle a social world that values profit over people and some people over others, a world that renders lives (of many people, most non-human animals, and the planet itself) expendable in the pursuit of perpetual economic growth.
Fundamentos da escatologia de samuel ramos
Authors: Pereira da Silva Filho Flávio
Published: September 2024

Esse é um estudo sobre os fundamentos da escatologia adotada por Samuel Ramos com o propósito de entender a natureza da teologia profética defendida pelo autor. A metodologia utilizada para esse fim é estabelecida sobre o comparativo de citações de Ramos com um conjunto de referências extraídas de fontes publicadas pela Igreja Adventista do Sétimo Dia, como o Tratado de Teologia Adventista do Sétimo Dia e a Série Darcom, publicada pela “Comissão de Daniel e Apocalipse” (em inglês DARCOM, conhecida em português como “Santuário e Profecias Apocalípticas”, em uma edição da Unaspress), da Associação Geral da Igreja Adventista, além de autores de relevância hermenêutica no meio adventista, como Gerhard Hasel, Jon Paulien e Ranko Stefanovic. Sob essa perspectiva, serão analisados detalhes do site oficial desse autor, vídeos publicados no YouTube, a monografia de 1987, que apesar da distância cronológica, é relevante no sentido da reconstrução histórica da mentalidade teológica do autor, e os três volumes sobre o livro de Apocalipse, com os dois volumes sobre o livro de Daniel, todos de autoria dele.
A Rare Case of Pulmonary Lymphoepithelial-Like Carcinoma
Authors: Tavares Mariana , Oliveira Marcos , Samouco Gonçalo , Ferreira Luís
Published: September 2024

N/a.
ATOS ILÍCITOS E A OBRIGAÇÃO DE INDENIZAR
Authors: Veras Ney Alves
Published: September 2024

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CÓDIGO DE TRÂNSITO BRASILEIRO: UMA VISÃO DE DESENVOLVIMENTO DE AÇÕES EDUCATIVAS PARA TRANSFORMAÇÃO E AQUISIÇÃO DE VALORES E ATITUDES
Authors: Lima Adriana Aparecida Moreira Ferreira de
Published: September 2024

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Critérios para Publicação [vigentes em 2001]
Authors: Editorial Equipe
Published: September 2024

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Evaluation of the outcomes of staging laparoscopy in intrahepatic cholangiocarcinoma patients undergoing surgical resection: a multicenter retrospective study in China
Authors: Qin Delong , Chen Jialu , Tang Yue , Li Zonglong , Geng Zhimin , Wu Hong , Qiu Yinghe , Song Tianqiang , Mao Xianhan , He Yu , Cheng Zhangjun , Zhai Wenlong , Li Jingdong , Liang Xiao , Lin Ruixin , Tang Di , Sun Chuandong , Tang Zhaohui
Published: September 2024

Aim: To evaluate the perioperative outcomes and postoperative survival of applying staging laparoscopy (SL) in intrahepatic cholangiocarcinoma (ICC) patients undergoing surgical resection.

Methods: A retrospective analysis was performed on all selected ICC patients who underwent curative-intent resection with/without applying staging laparoscopy from January 2010 to August December 2021. Perioperative outcomes and postoperative survival were analyzed. Propensity score matching (PSM) and inverse probability of treatment weighting (IPTW) were performed to reduce the bias due to confounding variables in the SL group and the non-SL group. Multivariate Cox analysis was used to ascertain the independent predictor of survival for ICC patients.

Results: A total of 279 patients (24.1%) were included in the SL group, while 881 patients (75.9%) were included in the non-SL group. Compared with the non-SL group, the SL group had lower blood loss, smaller tumor size, higher R0 resection rate, and shorter hospital stay, but a higher incidence of postoperative complications. The OS of the SL group was better than that of the non-SL group (Median OS: 31 months vs. 20 months). The 1-, 3-, and 5-year overall survival rates of the SL group were 77.9%, 45.1%, and 32.9%, respectively, while the non-SL group had rates of 63.9%, 31.3%, and 18.4%. SL was confirmed as an independent predictor of survival by multivariate Cox analysis.

Conclusion: ICC patients receiving SL had better perioperative outcomes and significantly prolonged overall survival after resection surgery. The subgroup analysis results support the use of routine SL.
Customer data protection mitigations: Building Baitul Mal wa Tamwil transaction data security system in Lampung
Authors: Ambarwati Diana , Hermanita Hermanita
Published: September 2024

IntroductionData security is a critical issue in today's digital age, exacerbated by the rampant online buying and selling of consumers’ personal data. This study focuses on the strategies employed by microfinance institutions, specifically Baitul Maal wa Tamwil (BMT), to protect member data and manage the associated risks.ObjectivesThe objective of this study is to describe mitigation strategies for data protection and risk management implemented by BMTs in Lampung. MethodThis field research employs qualitative methods, including observation and interviews, which are analyzed using the inductive thinking paradigm. Data collection focuses on BMTs' risk management practices and their cooperation with commercial banks to transfer risk.ResultsThe findings reveal that BMTs in Lampung have implemented effective risk-management strategies for data protection. Some BMTs transfer risk to commercial banks, a strategy known as risk transfer. Others adopt risk reduction and acceptance strategies by enhancing data security, training employees on system use, and managing existing risks to minimize business impact. ImplicationsThis study highlights the importance of robust data protection and risk management strategies to maintain customer trust in microfinance institutions. Effective risk mitigation ensures customer data security, thereby enhancing the credibility and sustainability of BMTs.Originality/NoveltyThis study contributes to the understanding of data security practices in microfinance institutions, particularly in the context of Islamic microfinance, by exploring practical mitigation strategies and their implementation.
Analysing the Socio-Economic Conditions of Waste Pickers in Uttar Pradesh
Authors: Gagan Alka , Anand Subhash , Rani Usha , Kumar Ashwani , Dubey Anupama
Published: September 2024

Waste pickers pick up reusable and recyclable waste from roadsides, dustbins, and landfills and sell it to local scrap dealers to earn money to fulfil their daily needs. Waste pickers do this in very unhygienic and hazardous conditions. This study examines the socio-economic status of waste pickers working in Ghaziabad using the Kuppuswamy SES (2020) scale. For this, 200 waste pickers, including male and female respondents, participated in this study. IBM SPSS software was used to code and analyse the data.  Correlation matrix and regression were used for analysis. The research found that although waste pickers are crucial to society, their socio-economic situation is among the lowest. 51% of waste pickers are from the lower middle class, and 42% are from the upper lower class. These waste pickers of our study are underprivileged, illiterate, and live in poor conditions. For a sustainable and decent living, they need the government to satisfy some of their needs, including free medical services, access to clean, fresh water, social safety, and training for alternative employment.
People-Centered Social Innovation as an Epistemological Alternative for Critical Recentering of People in the Development Agenda
Authors: Banerjee Swati
Published: September 2024

There are many complexities in today’s world, and alternatives are needed to open up spaces for truly reconfiguring people-centeredness in the current development agenda. This editorial piece, therefore, envisages a shift in the development narrative through the conceptualisation of people-centered social innovation that provides an epistemic alternative. The effort is to accelerate people-centered change through critically recentering people, especially marginalised groups and communities. This includes understanding the contextual and structural inequities, people’s knowledges and agency emerging from their embedded context, and institutionalising empowering spaces for actors that turn the wheel of social relations for epistemic justice.
Challenges and Advances in Cervical Cancer Prevention for HIV-Positive Individuals
Authors: Justiz-Vaillant Angel , Gopaul Darren , Asin-Milan Odalis , Arrozarena-Fundora Rodolfo , Thompson Reinand , Soodeen Sachin , Akpaka Patrick Eberechi , Unakal Chandrashekhar
Published: September 2024

Human papillomavirus (HPV) is a well-known cause of cervical cancer, with HIV infection exacerbating the prevalence of high-risk HPV (HR-HPV) and cervical intraepithelial neoplasia (CIN). ART has been shown to reduce the likelihood of developing squamous intraepithelial lesions (SILs) and HR-HPV prevalence, although its impact on invasive cervical cancer remains inconclusive. In a study in Accra, 250 sexually active HIV-positive women exhibited a high HPV prevalence, emphasising the need for regular screening. HPV testing, visual inspection with acetic acid (VIA), and cytology-based tests are primary screening methods, each with specific advantages and limitations. Cervical cancer rates in sub-Saharan Africa are alarmingly high, necessitating targeted vaccination and prevention strategies.
RNA Interference of Cytochrome P450s, CYP321A7 and CYP321A8, in Fall Armyworm Spodoptera frugiperda (J.E. Smith, 1797) (Lepidoptera: Noctuidae) Enhances Susceptibility to Chlorantraniliprole and Thiamethoxam
Authors: D. dela Cruz Raymund Kim , B. Alviar Karen
Published: September 2024

Fall armyworm (FAW), Spodoptera frugiperda, has been causing significant crop losses and has now become the most economically important pest of corn globally. With the challenges arising from the extensive use of synthetic chemicals such as reports that FAW gained resistance to various insecticides, researchers are developing environmentally sound control measures to address these issues. An example is the application of the RNA interference in managing FAW populations. RNA interference is a biological process where dsRNA molecules silence specific gene of interest. Here, dsRNA fragments were generated to target Cytochrome P450 monooxygenases CYP321A7 and CYP321A8 in FAW. Mortality and phenotypic effects of RNAi-mediated knockdown of essential genes of target CYP450s through RNAi in FAW were analyzed. Results showed that RNA in vitro transcription yielded ~14 μg/μL of dsCYP321A7 and dsCYP321A8. The mortality rate of dsCYP321A7- and dsCYP321A8-fed larvae following exposure to insecticide with dual active ingredient of Chlorantraniliprole and Thiamethoxam increased by 90% and 80%, respectively as compared to dsGFP-fed larvae with 40% at 2 days post insecticide exposure. This study provided evidence for the potential of RNAi for FAW management strategies particularly for insecticide-resistant populations, including the potential for biopesticide development.
Effectiveness of Diachasmimorpha longicaudata in Killing Ceratitis capitata Larvae Infesting Commercial Fruits in Dryland Agroecosystems of Western Argentina
Authors: Suárez Lorena del Carmen , Núñez-Campero Segundo Ricardo , Murúa Fernando , Garcia Flávio Roberto Mello , Ovruski Alderete Sergio Marcelo
Published: September 2024

Ceratitis capitata (Wiedemann) (medfly) strongly affects Argentinean fruit production and export. Augmentative biological control using the exotic parasitoid Diachasmimorpha longicaudata (Ashmead) is currently applied. The ability to find and parasitize medfly larvae on a wide diversity of fruit host species is a key issue to be analyzed. This research assessed the effect of the physical features of fruit on the preference of foraging D. longicaudata females and the influence of varying release density on parasitoid performance as a pest mortality factor in three fruit species. Trials were performed inside field cages under semi-arid environmental conditions in Argentina's central–western fruit-growing region. Sweet orange, peach, and fig were tested. Fruits were inoculated with third-instar larvae of the Vienna-8 temperature-sensitive lethal medfly strain. Naïve, 5-d-old mated D. longicaudata females were released in cages at 20, 40, 80 and 160 parasitoid densities. The highest levels of medfly mortality and parasitoid emergence were recorded in fig and peach, although D. longicaudata also induced mortality in orange, a fruit with few physical features favorable to parasitism. The medfly mortality in all fruit host species significantly increased with increased parasitoid females released into field cages. Diachsmimorpha longicaudata has high potential as a medfly biocontrol agent.
A Low-Cost Direct Digital Synthesis Based On-Chip Waveform Generation for Analog/Mixed Signal BIST Applications
Authors: Nti Darko Emmanuel , Bruce Isaac , Oko-Odion Ekaniyere , Bhatheja Kushagra , Karimpour Saeid , Chen Degang
Published: September 2024

Waveform generation as part of an on-chip built-in self-test (BIST) circuitry often necessitates sufficient linearity without expensive hardware overhead. Achieving high linearity is critical for accurate signal generation, especially in applications requiring high precision, such as biomedical and instrumentation. Currently, achieving the high linearity and precision required in signal generators often relies on costly hardware such as automated test equipment (ATE). This paper presents a DAC based hardware synthesizable arbitrary waveform generator. We use a low-cost DAC and a fully digital on-chip testing and calibration approach to nullify the effect of the DAC’s non-linearity on the generated waveform. The ultra-low cost and high linearity benefit of the proposed waveform generator makes it highly suitable for integration into resource-constrained systems. The proposed approach is validated using simulation results of the small-area DAC designed in TSMC 0.18um technology and the testing and calibration algorithms implemented in MATLAB. The DAC, designed with a matching accuracy at only the 5-bit level, is able to generate a signal with an ENOB of 12 bits alongside a SFDR and THD surpassing 100 dB. This high level of signal purity is consistently maintained across 100 Monte-Carlo simulations, demonstrating the robustness of the architecture against PVT variations as well as random mismatches.
The Pillars of the Societal Bioharmonism. A Conceptualist Contribution to the Evolution of the Contemporary Society
Authors: Gruia Romulus , Gaceu Liviu , Oprea Oana Bianca
Published: September 2024

This work refers to sustainability (SDG - Sustainable Development Goals) highlighting the idea of ​​harmony of life along the lines of the biological model at various levels and of nature alike, thus defining the concept of bioharmonism. The purpose of this paradigm is to find a way of transition in the contemporary societal change, connecting the natural sciences, more precisely the life sciences, with the social sciences, more concretely along the lines of holistic approaches to the evolution of human society. The objective of this point of view is related to sustainability, resilience and planetary health, which indicates the need to analyse planetary bioharmony and transpose the model to the structure and functionality of human society through the complex, unitary and coherent approach of the bioharmonization process. The study analyses the issue, through: the definition and role of societal bioharmonism, then the argument related to the transition to another world using the proposed path, based on specific notions, principles and laws, and finally, the description of some lines of application of the pillars of bioharmonism. A series of solutions are highlighted that can contribute conceptually to the evolution of contemporary society, to the convergence of anthroposystems with ecosystems by interconnecting the aspects of the biological revolution with those specific to the information age. The solutions aim at societal bioharmonization supported by its specific pillars, which through integration and emergence lead to a dynamic balance. The state of equilibrium, sustainability can be highlighted at a systemic level by the directions of action in which the bioharmonization complementarities that indicate the Environment and biodiversity in the economic equation, the Citizen in the social equation and Science in the political equation will be taken into account.
Leveraging Long-Context Large Language Models for Multi-Document Understanding and Summarization in Enterprise Applications
Authors: Godbole Aditi , George Jabin Geevarghese , Shandilya Smitha
Published: September 2024

The rapid increase in unstructured data across various fields has made multi-document comprehension and summarization a critical task. Traditional approaches often fail to capture relevant context, maintain logical consistency, and extract essential information from lengthy documents. This paper explores the use of Long-context Large Language Models (LLMs) for multi-document summarization, demonstrating their exceptional capacity to grasp extensive connections, provide cohesive summaries, and adapt to various industry domains and integration with enterprise applications/systems. The paper discusses the workflow of multi-document summarization for effectively deploying long-context LLMs, supported by case studies in legal applications, enterprise functions such as HR, finance, and sourcing, as well as in the medical and news domains. These case studies show notable enhancements in both efficiency and accuracy. Technical obstacles, such as dataset diversity, model scalability, and ethical considerations like bias mitigation and factual accuracy, are carefully analyzed. Prospective research avenues are suggested to augment the functionalities and applications of long-context LLMs, establishing them as pivotal tools for transforming information processing across diverse sectors and enterprise applications.
A Comprehensive Study on the Prediction of Concrete Compressive Strength
Authors: ALTUNCI YUSUF TAHİR
Published: September 2024

There is an extensive body of research in the literature focusing on predicting the mechanical properties of concrete, such as compressive strength. Summarizing the current studies following the valuable contributions of researchers will serve as a guide for future studies and researchers. To this end, this study aims to identify the key authors, sources, institutions, and countries that have contributed to the prediction of concrete compressive strength. Additionally, it aims to provide researchers with comprehensive information on prominent research themes, trends, and gaps in the literature related to the prediction of concrete compressive strength. For this purpose, 2319 articles on the prediction of concrete compressive strength published from 2000 to 19th August 2024 were identified through the Scopus Database. The scientific measurement analyses were conducted using VOSviewer software. Upon reviewing the relevant research, it was found that machine learning methods are frequently used in predicting concrete compressive strength. In this context, the study will make significant contributions to the literature by examining leading institutions, countries, authors, and sources in the field, synthesizing data, and highlighting research areas, gaps, and trends related to concrete compressive strength prediction.
Chaotic Dynamics, Sequence Density, and Chaos Suppression: A Study in Euclidean and Riemannian Spaces Inspired by Collatz-like Problems
Authors: zeraoulia Rafik
Published: September 2024

In this paper, we explore the surprising behavior of certain discrete maps, drawing inspiration from Collatz-like problems and advanced techniques in analytic number theory, dynamical systems, and differential geometry. Specifically, we investigate a driven cubic-quintic Duffing equation and predict the number of limit cycles around equilibrium points. Furthermore, we develop a novel theoretical framework for chaos suppression in damped-driven systems, leveraging sequences derived from Collatz-like problems. Our study also focuses on analyzing the density of these sequences in both Euclidean and Riemannian metric spaces, providing a comparative analysis of their distribution properties. We estimate the growth rate of sequence density analytically and numerically, highlighting the sensitivity of the density values to the choice of parameters in both metric spaces. Our results present new insights into the behavior of these sequences and their implications for number theory, chaotic dynamics, and geometric analysis.
Structural Basis of the Activity of HER2-Targeting Construct Composed of DARPin G3 and Albumin-Binding Domains
Authors: Konshina Anastasia G. , Bocharov Eduard V. , Konovalova Elena V. , Schulga Alexey A. , Tolmachev Vladimir , Deyev Sergey M. , Efremov Roman G.
Published: September 2024

Non-immunoglobulin based scaffold proteins (SPs) represent one of the key therapeutic target-specific and high-affinity binders in modern medicine. Among their cellular targets are signaling receptors, in particular, receptor tyrosine kinases, whose dysfunction leads to the development of cancer and other serious diseases. Successful applications of SPs have been reported for HER receptor type 2 (HER2), the member of the human epidermal growth factor receptor family that regulates the cell growth and differentiation. To extend blood residence of SPs and prevent their high accumulation in kidney, these proteins are often fused with serum albumin. Promising results for the HER2-binding activity were obtained for SP G3 from DARPins (Designed Ankyrin Repeat Proteins) family fused with albumin-binding domain (ABD) [1]. Interestingly, detected HER2-G3 binding strongly depended on the position of G3 module in the sequence of the constructs. Further improvement of these constructs for biomedical applications requires deciphering the molecular mechanism responsible for this effect. Here, we investigate the structural and dynamic aspects of ABD-G3 and G3-ABD chimeras using NMR spectroscopy and molecular modeling. Based on biophysical data, we came to the conclusion that extensive interdomain contacts form in both constructs, although the binding interfaces and complex stability are somewhat different. Also, it was shown that the domain linker plays an important role – it limits the accessibility of detected protein-protein binding sites depending on the order of the domains in chimeric molecules. The results create a solid structural basis for the rational design of new effective SP-constructs targeting signaling receptor in the cell.
Exosome-Derived microRNAs in Hypertrophic Cardiomyopathy
Authors: Wang Brian Xiangzhi
Published: September 2024

Hypertrophic cardiomyopathy (HCM) poses a significant health burden worldwide, characterized by myocardial hypertrophy and increased risk of sudden cardiac death. Recent studies have revealed the involvement of exosome-derived microRNAs (miRNAs) in the pathogenesis of HCM, shedding light on novel regulatory mechanisms in cardiac remodeling and dysfunction. This literature review synthesizes current evidence on the role of exosome-derived miRNAs in HCM. It discusses key miRNAs identified from diverse cellular origins, including cardiomyocytes, stem cells, and conduction cells, elucidating their contributions to hypertrophic signaling pathways, fibrosis, and changes in cellular metabolism. Notable miRNAs highly expressed in exosomes such as miR-1, miR-133, and miR-208 are highlighted for their implications in HCM pathophysiology. Moreover, the review explores the diagnostic and therapeutic potential of exosome-derived miRNAs as biomarkers and therapeutic targets in HCM management. The studies summarized in this review demonstrate that exosome-derived miRNAs play a crucial role in orchestrating the molecular events underlying HCM, offering new insights into disease mechanisms and potential therapeutic avenues. Understanding the intricate interplay between exosome-mediated miRNA communication and HCM pathophysiology holds promise for the development of personalized diagnostic tools and targeted therapies to improve patient outcomes in HCM.
Impact of the COVID-19 Pandemic on the Detection of Leprosy in Micro-Regions with a High Risk of Illness in Minas Gerais, Brazil
Authors: Vidal Sarah L , Lages Daniele dos S. , Maciel Isabela C. L. , Leite Isabel C. G. , Coelho Angélica da Conceição Oliveira , Lana Francisco C. F.
Published: September 2024

Background: Leprosy control remains challenging in Brazil and has been aggravated by the Covid-19 pandemic. Objective: To analyze the impact of the Covid-19 pandemic on the epide-miological scenario of leprosy through the detection rate of new cases, risk of illness and hidden prevalence according to high-risk micro-region in Minas Gerais, Brazil. Methods: Ecological study conducted in the health micro-regions, using data on new leprosy cases diagnosed between 2015 and 2023. The annual detection rate of new cases, the Risk of Illness Index and the Hidden Preva-lence were evaluated. The time trend was evaluated by calculating the Annual Percentage Change (APC) of the detection rate, based on segmented linear regression. Results: A reduction in the detection of new cases was identified in most of the micro-regions evaluated. Minas Gerais and some micro-regions showed a positive increase in the variation of the overall detection rate in 2021. The reduction in hidden prevalence in certain micro-regions is linked to the reduction in diagnoses, especially those cases with installed physical disability. Despite the reduction in the risk of becoming ill with leprosy in some micro-regions, Minas Gerais showed an increase in risk. Conclusions: The pandemic has had a considerable and heterogeneous impact on the detection of new cases, as well as on the risk of becoming ill and the hidden prevalence, with repercussions for the control of the endemic in populations. There is a need to implement public health policies that prioritize the early identification of cases and ensure that vulnerable populations are monitored.
Quality of Life and Symptom Burden in Non-Small Cell Lung Cancer Patients Receiving Second-Line Chemotherapy Compared with Immunotherapy
Authors: Stylianou Christos , Kalemikerakis Ioannis , Konstantinidis Theocharis , Kafazi Alkmena , Alevizopoulos Nektarios , Parissopoulos Stelios , Govina Ourania
Published: September 2024

Background and Objectives: The burdened symptomatology accompanying advanced non-small cell lung cancer (NSCLC) is associated with poor prognosis and lower quality of life (QoL). Although both chemotherapy and immunotherapy increase survival, they are still associated with reduced functionality due to their toxicity. This study aimed to estimate the QoL and symptom burden of NSCLC patients receiving second-line chemotherapy compared to patients receiving second-line immunotherapy. Materials and Methods: This comparative, prospective study, conducted from January 2020 to December 2021, included 111 NSCLC patients who were divided into two groups: 61 patients receiving second-line chemotherapy and 50 patients receiving second-line immunotherapy. Patients QoL and symptom burden were estimated using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ C-30) (value range 0 - 100) from treatment cycle 1 to 6. Results: The QoL (mean score > 50) and functionality dimensions (mean score > 50) were moderate to good in both treatment groups, while the symptoms burden did not appear to be a serious problem (mean score < 50). From cycle 3 to cycle 5, the QoL was significantly better in the immunotherapy group. From cycle 3, role and social functioning scores were higher in the immunotherapy group, while emotional and cognitive functioning were higher from cycle 2 (p < 0.05). The chemotherapy group experienced higher levels of nausea/vomiting, constipation and financial difficulties in all cycles (p < 0.05). Fatigue and appetite loss were significantly greater from cycle 2 and insomnia was significantly greater from cycle 3. On the contrary, the immunotherapy group experienced higher levels of diarrhea in cycles 5 and 6 (p < 0.05). Conclusions: Although both therapy groups did not report significantly impaired QoL and severe symptoms, it seems that QoL improved in the immunotherapy group, which reported less symptom burden compared to the chemotherapy group.
Determinant Factors of Entrepreneurial Culture in University Students: An Analysis from the Theory of Planned Behavior at a Peruvian University
Authors: CHAVEZ VERA KERWIN JOSE , ALDERETE VELITA JOEL JOAB , ALCALA MARTINEZ TOMAS , FERRER RAUL MARCELO
Published: September 2024

This study analyzed the influence of attitude toward innovation and creativity, entrepreneurial self-efficacy, and institutional support in the consolidation of an entrepreneurial culture among Peruvian university students, using the Theory of Planned Behavior (TPB) as the theoretical framework. Data were collected from 948 students through a validated 29-item questionnaire, and the data analysis was conducted using the PLS-SEM method. The results showed that both attitude toward innovation and entrepreneurial self-efficacy have a significant positive impact on entrepreneurial culture, and entrepreneurial self-efficacy acted as a partial mediator in this relationship. However, external resources and institutional support were not significant mediators between entrepreneurial intention and entrepreneurial culture. This study expands the understanding of TPB in the Peruvian context, highlighting the importance of fostering self-efficacy and an innovative attitude in students to strengthen entrepreneurial culture in universities. Educational institutions should consider these key factors when designing programs that promote entrepreneurship.
Physics-Informed Neural Network for Solving a 1-Dimensional Solid Mechanics Problem
Authors: Singh Vishal , Mallick Rajnish , Saxena Sahaj , Dhawan Sharanjeet , Sahni Manoj , Harursampath Dineshkumar
Published: September 2024

Our objective in this work is to demonstrate how Physics-Informed Neural Networks,
a type of deep learning technology, can be utilized to examine the mechanical properties
of a helicopter blade. The blade is regarded as a prismatic cantilever beam that is
exposed to triangular loading, and comprehending its mechanical behavior is of utmost
importance in the aerospace field. PINNs utilize the physical information, including differential
equations and boundary conditions, within the loss function of the neural network
to approximate the solution. Our approach determines the overall loss by aggregating
the losses from the differential equation, boundary conditions, and data. We employed a
Physics-Informed Neural Network (PINN) and an Artificial Neural Network (ANN) with
equivalent hyperparameters to solve a fourth-order differential equation. By comparing
the performance of the PINN model against the analytical solution of the equation and
the results obtained from the ANN model, we have conclusively shown that the PINN
model exhibits superior accuracy, robustness, and computational efficiency when addressing
high-order differential equations that govern physics-based problems. In conclusion,
the study demonstrates that PINN offers a superior alternative for addressing solid mechanics
problems with applications in the aerospace industry.
Floater Assembly and Turbine Integration Strategy for Floating Offshore Wind Energy: Considerations and Recommendations
Authors: Ivanov Glib , Ma Kai-Tung
Published: September 2024

The increasing demand for cost-effective floating offshore wind turbines (FOWT) necessitates streamlined mass production and efficient assembly strategies. This research investigates the assembly and integration of 15 MW FOWT floaters, utilising a semi-submersible floater equipped with a 15 MW wind turbine. The infrastructure and existing port facilities of Taiwan are used as an example. The effectiveness of various assembly and integration strategies has been evaluated. The study outlines equipment and infrastructure requirements for on-quay floater and turbine assembly, comparing on-quay assembly versus construction at remote locations and subsequent towing. Detailed analyses of port operations, crane specifications, and assembly procedures are presented, emphasizing the critical role of crane selection and configuration. The findings indicate that on-quay assembly at one major port is feasible and cost-effective, provided that port infrastructure and operational logistics are optimised. This research offers insights and recommendations for implementing large-scale FOWT projects, contributing to advancing offshore wind energy deployment.
A Review of Crowd Abnormal Behavior Recognition Technology Based on Computer Vision
Authors: Zhao Rongyong , Hua Feng , Wei Bingyu , Li Cuiling , Ma Yulong , Wong Eric S. W. , Liu Fengnian
Published: September 2024

Crowd abnormal behavior recognition is one of the research hotspots in computer vision. Its goal is to use computer vision technology and abnormal behavior detection models to accurately perceive, predict, and intervene in potential abnormal behaviors of the crowd, and monitor the status of the crowd system in public places in real-time, to effectively prevent and deal with public security risks and ensure public life safety and social order. To this end, focusing on the crowd abnormal behavior recognition technology in the computer vision system, a systematic review study of its theory and cutting-edge technology is conducted. First, the crowd level and abnormal behaviors in public places are defined, and the challenges faced by crowd abnormal behavior recognition are expounded. Then, from the dimensions based on traditional methods and based on deep learning, the mainstream technologies of abnormal behavior recognition are discussed, and the design ideas, advantages, and limitations of various methods are analyzed. Next, the mainstream software tools are introduced to provide a comprehensive reference for the technical framework; Secondly, typical abnormal behavior datasets at home and abroad are sorted out, and the characteristics of these datasets are compared in detail from multiple perspectives such as scale, characteristics and uses, and the performance indicators of different algorithms on the datasets are compared and analyzed; Finally, the full text is summarized and the future development direction of crowd abnormal behavior recognition technology is prospected.
Origins of Attractive Gravitational and Boson Forces, and Wave Mechanics of the Elementary Particles
Authors: Hwang Jae-Kwang
Published: September 2024

In the standard model (SM) and general relative theory (GR) based on the 4-D Minkowski space, the graviton and photon are massless. In that case, two particles with the positive masses are attracted to each other by the gravitational (graviton) waves. The origin of the attractive gravitational force is not understood in terms of SM and GR. In the present work, the 3-D quantized space model (TQSM) based on the 4-D Euclidean space is applied to explain the attractive gravitational force. The repulsive Coulomb force between two particles with the positive charges is explained by using the destructive interference of the electric waves emitted from two particles. Therefore, the destructive interference of the gravitational (graviton) waves emitted from two particles with the positive masses should make the repulsive gravitational force (Fr). The observance of the attractive gravitational force (Fg) indicates the non-zero graviton mass because the attractive gravitational force can be explained if the gravitational (graviton) waves are the oscillating mass waves. The masses lost during the destructive interference of the gravitational (graviton) waves are converted to the gamma rays. These induced gamma rays make the new attractive force (Fa). The observed attractive gravitational force (Fg) should be originated by the equation of Fg = Fa – Fr > 0. This can explain the reason why the gravitational force (Fg) between the elementary particles is so weak when compared with the Coulomb forces. The properties of elementary particles in terms of the TQSM model are analyzed by the wave mechanics of G, E and M waves of the 3-D quantized photon space. The G wave is the time fluctuations along the (absolute) time axis and E (electric) and M (magnetic) waves are the space fluctuations along the space axes. The elementary particles exist as the particle forms with the constant (rest) masses (m) at the low speed. The elementary particles at the high speed have the (particle) wave forms with the oscillating masses or the particle forms with the relativistic masses (gm). The graviton has the very small mass moving with the very high-speed close to the light speed of c. This means that most of the gravitons exist as the graviton wave forms. The particle waves are coupled with the photon waves (2EM, gamma rays) because of the energy conservation. It is concluded that the gravitational waves are the coupled oscillating forms (GEM waves) of the graviton waves and photon waves. The existence of the wave forms for the particles can explain the double slit experiment for the electron beams. And the attractiveness of the dark matter, weak and strong forces is explained by the virtual two boson processes with the TC symmetry and total energy conservation. All elementary bosons and neutrinos are considered as the wave forms with the high speed close to the light speed of c. Because of the charge and energy conservations, only the neutrino oscillations and dark matter (baston) oscillations are allowed.
Characterization and Optimization of Boride Coatings on AISI 1137 Steel: Enhancing Surface Properties and Wear Resistance
Authors: Genç Asım , Urtekin Levent , DANIŞMAZ Merdin
Published: September 2024

This study investigates the optimization of boron coating parameters for medium carbon steels, specifically AISI 1137, and their subsequent effects on mechanical properties, which are crucial for industrial applications. Despite extensive research on boronizing processes, an understanding of the optimal conditions that enhance wear resistance and hardness while maintaining structural integrity is still lacking. To address this gap, we systematically examined the impact of boronizing temperatures (850 °C and 950 °C) and durations (2, 4, and 8 hours) on the structural and mechanical properties of AISI 1137 steel. Our findings indicate the need for improved surface properties in medium carbon steels used in demanding environments, such as automotive and machinery components. The boronizing process was carried out using Ekabor 1 powder, with characterization performed through optical microscopy, pin-on-disk wear tests, and Vickers hardness analysis. Results showed that the thickness of the boronized layer ranged from 50.6 μm to 64.8 μm, with wear resistance increasing by 1.8 to 3.9 times at 950 °C compared to 850 °C. The measured hardness of the boronized surface layers varied between 1963.7 HV and 219.3 HV, decreasing from the boronized layer toward the base material. The optimal parameters for wear resistance and hardness were found to be a temperature of 950 °C and a duration of 8 hours, facilitating the formation of FeB and Fe2B phases, which significantly enhanced the steel's mechanical properties. This research provides valuable insights into the boronizing process and establishes a foundation for optimizing surface treatments to extend the lifespan and performance of medium carbon steels in industrial use.
Mild Traumatic Brain Injury in Yucatan Minipigs: Assessing Changes in Approachability/Sociability and Mechanical Nociception Following Central Fluid Percussion Injury
Authors: Pavlichenko Mark , Lilova Radina , Logan-Wesley Amanda , Gorse Karen , Lafrenaye Audrey D.
Published: September 2024

Traumatic brain injury (TBI) is a global healthcare concern affecting millions, with wide-ranging symptoms including sensory and behavioral changes that can persist long-term. Due to similarities with human brain cytoarchitecture and inflammation, minipig models are advantageous for translational TBI research. However, gaps in knowledge exist regarding their behavioral and sensory sequelae following injury. Therefore, in this study, we assessed changes in approachability using a forced human approach task (FHAT) and mechanical nociception using the von Frey Test in adult male and female Yucatan minipigs for up to one week following a sham or central fluid percussion injury (cFPI). Specifically, the FHAT assessed each animal’s response to a forced interaction with either a known or unknown experimenter. To evaluate changes in nociceptive sensory sensitivity, von Frey monofilaments ranging from 0.008 to 300 grams of force were applied to the pinna of the ear or base of the tail. We found that forced approachability was affected by experimenter familiarity as well as cFPI in a sex-specific manner at subacute timepoints. We also found reductions in sensitivity following cFPI on the ear in male minipigs and on the tail in female minipigs. Overall, the current study demonstrates that cFPI produces both behavioral and sensory changes in minipigs up to one-week post-injury.
Electronic Nursing Record - Importance for Nursing and Benefits of Implementing it in Health Information Systems
Authors: Taneva Daniela Ivova , Gyurova-Kancheva Vasilka Todorova , Kirkova-Bogdanova Angelina Georgieva , Paskaleva Diana Angelova , Zlatanova Yovka Tinkova
Published: September 2024

Introduction: The advancement of nursing science and practice necessitates the documentation of information, which is increasingly being recorded in electronic mediums due to the progress of information technology. Various countries around the world have implemented electronic nursing records (ENRs) or are in a process of implementing it. This study aims to ascertain the significance of electronic nursing records and consolidate their primary benefits for nursing. Methods: The study utilized an established scoping review methodology (Arksey and O‘Malley protocol; JBI method; PRISMA 2020). Results: Out of 6970 initial articles extracted from 4 databases, 36 were included in the study. Several essential elements for structuring, introducing, and emphasizing the importance of ENRs have been recognized, including the availability of standardized terminology, enhancement of nursing care quality, advancement of research activity, integration with electronic systems, optimization of healthcare, and conditions for ENR integration. Conclusion: Electronic nursing records are indispensable and beneficial for enhancing care quality, improving patient safety, and affirming the autonomy of the nursing profession.
Stable Microclimates and Autonomic Modulation in Horses Sin-Gle-Stall Housed in Different Stable Architectures During Mon-Soon in a Tropical Savannah Environment
Authors: Poochipakorn Chanoknun , Sanigavatee Kanokpan , Leelehapongsathon Kansuda , Wonghanchao Thita , Chanda Metha
Published: September 2024

The influence of climate conditions and stable design on horses housed in single stalls can have significant effects, especially in regions with tropical savannah climates. A recent study observed variations in autonomic responses in horses housed in different stable designs during the summer, but there is limited information about their conditions during the monsoon. This study investigated the stable microenvironment and autonomic regulation of horses housed in different stable archi-tectures during the monsoon in a tropical savannah environment. Twenty-two horses were allo-cated to one of three stable architectures, each with varying stable microenvironments. The findings reveal that the heart rate variability (HRV) was lower in horses in a stable with a solid external wall and lower volume-to-horse ratio compared to those in a stable with a solid external wall but a higher volume-to-horse ratio or one without a solid external wall. Additionally, the study found that stable microenvironments and HRV modulation were correlated with stable architecture. Autonomic responses differed among horses in different stable architectures, indicating that stable microen-vironments and, to some extent, volume-to-horse ratio play a role in horses’ autonomic regulation. The findings have implications for improvements in housing and welfare in tropical savannah environments.
Redox Signaling in Endosomes on the Example of EGF Receptors
Authors: Hebchen Dana Maureen , Schröder Katrin
Published: September 2024

Early Endosomes represent first line sorting compartments or even organelles for internalized molecules. They enable the transport of molecules or ligands to other compartments of the cell, such as lysosomes for degradation or recycle them back to the membrane by various mechanisms. Moreover, early endosomes function as signaling and scaffolding platform to initiate or prolong distinct signaling pathways. Accordingly, early endosomes have to be recognized as either part of a degradation or recycling pathway. The physical proximity of many ligand-binding receptors with other membrane bound proteins or complexes such as NADPH oxidases may result in an interaction of second messengers like reactive oxygen species (ROS) and early endosomes that promote correct recognition of individual early endosomes. In fact, redoxosomes comprise an endosomal subsection of signaling endosomes. One example of such potential interaction is epidermal growth factor receptor (EGFR) signaling. Here we summarize recent findings on EGFR signaling as a well-studied example for receptor trafficking and trans-activation and illustrating the interplay between cellular and endosomal ROS.