bluuebunny/crossref_metadata_2025 huggingface dataset:
Improving Strategic Decision-Making in a Closed-Loop Rail Network with Hybrid Simulation-Optimization Modeling
Authors: Pedreira Junior Jorge Ubirajara , Nascimento Ademar Nogueira do , Fontes Cristiano Hora de Oliveira
Published: May 2019

The availability of rail infrastructure resources is a major driver of rail operations performance.  To evaluate the impact of infrastructure provision, network simulation models can be used to accurately represent train traffic behavior in a wide range of scenarios. However, performing this task can result in a problem of high combinatorial nature as the number of factors and their associated levels increase. This requires more sophisticated techniques such as experimental design formulations or optimization modeling in order to yield satisfactory results. Yet the research in network simulation models for rail systems has hitherto been limited to simple what-if analysis, made up from few factors that cannot represent the whole spectrum of interventions. This is especially critical in closed-loop rail systems where trains are subject to various interferences. Local improvements can be misleading as the queues are merely transferred within the network. Considering this, we propose a hybrid simulation-optimization model to aid the strategic decision of minimizing supplementary capital costs in a heavy-haul Brazilian railroad under construction. As soon as the railroad is completed, investments in both loading and unloading rail terminals will be necessary. First, we developed a representative and flexible model capable of dealing with complex relations between variable infrastructure provision and the resulting operational performance. Then, we simulated this system to prove that the current set of proposed infrastructure resources cannot meet the transportation demands. Afterwards, we demonstrate that local improvements can be delusive as the queues are shifted from loading to unloading operations, reciprocally. Then, we solve an optimization model to define the minimal supplementary investment in order to meet the commercial goals of mining companies. This is done by choosing the best trackage configuration, equipment quantity and capacity and fleet sizing in 3 different production scenarios. The best values of the objective function were found by improving both loading and unloading equipment and increasing the number of trains.
Alzheimer's in Post-Industrial Epoch
Authors: Kholmanskiy Alexander
Published: May 2019

Study nature of epidemiological risk factors and patterns of distribution of mortality from Alzheimer's (DA) in 160 countries. An exponential Malthus model was used to construct adequate approximations of statistical data. Proportionality of average lifetime after 55 years (Δt) to education index (Ψ) was established. Ranking of countries by increasing value of ΨΔt showed that DA depends exponentially on ΨΔt and all countries can be divided into three groups in accordance with level of their economic development. In series of countries of low, medium and highly developed, their average values of DA increase exponentially. Growth of DA in developed countries in post-industrial epoch was explained by emergence of a new risk factor Alzheimer's of a mental nature. A mismatch of complexity or, on contrary, primitiveness of profession with level of mental development of worker, provokes development of chronic stress in him, fraught with pathologies of cognitive function metabolism in elderly. The geography of Alzheimer's disease was explained by the dependence of the human mentality on latitudinal climate change and on the chiral factor of a solar nature acting at night on a sleeping person.
ROL BELİRSİZLİĞİ VE SANAL KAYTARMA: GÖRGÜL BİR ARAŞTIRMA
Authors: GÜĞERÇİN Utku , SIĞIRCIKOĞLU Emel Berkem
Published: May 2019

Çalışanların görev, yetki ve sorumluluklarının net olarak tanımlanmamış olması ve/veya görevleri ile ilgili olarak kendilerinden beklenilen davranışların çalışanlara açıkça bildirilmemesi rol belirsizliği olarak adlandırılmaktadır. Rol Teorisi’nden hareketle; rol belirsizliği yaşayan çalışanların, maruz kaldıkları stresten dolayı üretkenlik ve performans karşıtı davranışlara yönelebileceklerini öngörülmektedir. Rol belirsizliğine verilen tepkiler farklılaşmakla birlikte, işyerlerinde artan internet kullanımı neticesinde çalışanlar, rol belirsizliğine tepki olarak sanal kaytarma davranışlarına yönelebilirler. Bu bağlamda bu araştırmanın amacı rol belirsizliğinin, ‘dijital çağın kahve molası’ şeklinde tanımlanabilecek sanal kaytarma davranışlarını nasıl etkilediğini ortaya koymaktır. Araştırma; özel sektör çalışanları üzerinde, anket yöntemi kullanılarak gerçekleştirilmiştir. Analiz sonuçlarına göre çalışanların yaşadıkları rol belirsizliği, sanal kaytarma davranışlarını artırmaktadır. Bu doğrultuda, çalışanlara daha az rol belirsizliği yaşayacakları bir çalışma ortamı sunularak, mesai saatleri içerisinde kişisel amaçlı internet kullanımının azaltılmaya çalışılması önerilmektedir.
The central mechanism of tadalafil vs Chaihu-Shugan-San capsule for psychogenic erectile dysfunction: a magnetic resonance imaging study protocol of a randomized placebo-controlled trial
Authors: Ren Feiqiang , Ma Ziyang , Zhang Ling , Dong Liang , Chen Diang , Chang Degui , Zhang Peihai , Li Guangsen , Huang Xiaopeng , You Yaodong , Yu Xujun , Yang Fang , Li Zhengjie
Published: May 2019

Background: Erectile dysfunction (ED) affects many adult men worldwide. Many studies on the brain of psychogenic ED have shown significant cerebral functional changes and reduced volume of gray matter and white matter microstructural alterations in widespread brain regions. We design this study to provide both an enhanced level of evidence of central mechanism research and an evidence-based treatment option for patients suffering from psychogenic ED. Furthermore, we also aim to provide a new evidence as well as an innovation of the clinical treatment in psychogenic ED.
Method and Analysis: This study is designed as a multi-center, three-arms, randomized trial. From the perspective of psychogenic ED, we will divide patients into three groups, which are placebo group, tadalafil group and CHSGS group. 135 patients will be randomly allocated to receive placebo, CHSGS capsule or tadalafil oral pharmacotherapy. After the period of 4-week treatment, the outcome of primary assessment changes in the IIEF-5, EHS and QEQ total scores from baseline. Secondary assessments include the SEAR, HAMA-14, HAMD-17 scores, response rate of the patients and their partners. Apart from brain MRI from baseline, we will also attach great importance to other changes in the follow-up four weeks.
Discussion: We expect that the results of this trial can provide both an enhanced level of evidence for central mechanism research and an evidence-based treatment option for patients suffering from ED, as well as to provide an innovation of the clinical treatment in psychogenic ED.
Cognitive impairments in patients with persistent symptoms attributed to Lyme disease
Authors: Berende Anneleen , Rentergem Joost Agelink van , Evers Andrea W. M. , Hofstede Hadewych J. M. ter , Vos Fidel J. , Kullberg Bart Jan , Kessels Roy P.C.
Published: May 2019

Background:
Persistent symptoms attributed to Lyme borreliosis often include self-reported cognitive impairment. However, it remains unclear whether these symptoms can be substantiated by objective cognitive testing.

Methods:
For this observational study, cognitive performance was assessed in 280 adults with persistent symptoms attributed to Lyme borreliosis (as part of baseline data collected for the Dutch PLEASE study). Cognitive testing covered the five major domains: episodic memory, attention, verbal fluency, information-processing speed and executive function. Patients’ profiles of test scores were compared to a large age-, education- and sex-adjusted normative sample using multivariate normative comparison. Performance validity was assessed to detect suboptimal effort, and questionnaires were administered to measure self-reported cognitive complaints, fatigue, anxiety, depressive symptoms and several other psychological factors.

Results:
Of 280 patients, one was excluded as the test battery could not be completed. Of the remaining 279 patients, 239 (85.4%) displayed sufficient performance validity. Patients with insufficient performance validity felt significantly more helpless and physically fatigued, and less orientated. Furthermore, they had a lower education level and less often paid work. Of the total study cohort 5.7% (n=16) performed in the impaired range. Among patients who displayed sufficient performance validity, 2.9% (n=7) were classified as cognitively impaired. No association between subjective cognitive symptoms and objective impairment was found.

Conclusions:
Only a small percentage of patients with borreliosis-attributed persistent symptoms have objective cognitive impairment. Performance validity should be taken into account in neuropsychological examinations of these patients. Self-report questionnaires are insufficiently valid to diagnose cognitive impairment.
An assessment of the level of awareness of e-health among Saudi medical students
Authors: Aldebasi Bader , Alhassan Abdulaziz I. , Al-Nasser Sami , Abolfotouh Mostafa A.
Published: May 2019

Background: Previous studies described the levels of awareness of patients and health care providers on e-health in general and on e-health for a certain condition/disease. However, none of these studies was conducted in Saudi Arabia. The aims of this study were 1)To determine the levels of knowledge, attitude and practice of medical students on e-health, and 2) To identify the predictors of e-health practice among medical students. Methods: A cross-sectional survey of 440 medical students at the college of medicine, King Saud bin-Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia, was conducted, during October/November 2019, using a previously validated questionnaire, to assess: (1) knowledge in three domains; e-health definition (13 statements), fields of application of e-health (8 statements), methods of using e-health (7 statements), (2) attitude toward using e-health (8 statements) and (3) reported practice of e-health in medical training (5 statements). A scoring system was used to calculate the total and percentage score of knowledge, attitude and practice for each student. Multiple regression analysis was applied to identify predictors of e-health practice. Significance was considered at p<0.05. Results: Of the 440 medical students surveyed, the majority were females (55.7%), of stream type1 (79.8%) and from families whose monthly income was more than 10,000SR (82.8%). Overall knowledge about e-health was unsatisfactory (PMS=71.62%), with only 43.6% of all students reporting satisfactory level. However, this level was satisfactory for fields of application (Percentage mean score-PMS=76.43%) and unsatisfactory for definition of e-health (PMS=70.69%) and methods of its use (PMS=65.69%) domains. Overall attitude towads e-health use was positive (PMS=82.32%), with nearly three-quarters of all students (73.4%) reporting positive attitude. Generally, good level of practice of e-health was reported by students (PMS=84.27%), with more than three-quarters of medical students (78.4%) reporting good practice. Adjusting for age, gender, stream, educational grade and family monthly income, good practice was significantly predicted with higher knowledge (t=2.219, p=0.027) and attidude (t=2.114, p=0.035) scores. Conclusion: This study provides basic information regarding medical students’ knowledge, attitude, and practice on e-health. More resources should be directed to elevate medical students’ knowledge and to motivate them to practice e-health using the available tools.
The Problem of Cultural Identity in the Contemporary Archaeological Practice
Authors: Kuzmanović Zorica
Published: May 2019

The decades-long reconsideration of the concept of culture in archaeology has been aimed at overcoming the traditional culture-historical concept, assuming culture as a relatively stable and homogeneous system of values characteristic of a certain group or a community of people. The practice of cultural classification of artefacts, based upon the premise that people linked by the production and usage of stylistically homogeneous material culture form a group with the feeling of communal identity, has been criticized as a reflection of ethnocentric projection of the modern idea of cultural identity.

In spite of numerous critics of this concept, developed under the influence of various theoretical strains from the beginning of the 1960s, it seems that the implicit assumption is still present of the communal cultural identity of a group linked by the communal material culture. Furthermore, an attempt to counteract the critique and offer a multicultural interpretation of the past brings in the danger to rehabilitate the very concept of culture which archaeology has been trying to abandon for decades.
Savage Man as the Measure of Alterity
Authors: Milosavljević Monika
Published: May 2019

The notion of savage man came into being through one of the most vital issues raised by the people in the past – that of humanity. Even in the most ancient written sources, savage man is introduced as a defining notion of the demarcation between the world of humans and the world of animals. On the other hand, this notion can be taken as a relational phenomenon of imagination, whose chronological changes are indicative of the reverse side of “normality” under various social circumstances. The subject of this paper is the idea of savage man as the Other in the history of archaeological ideas. The idea entered archaeology along with the concept of savagery, by which anthropology ensured the position of allochronic discourse among scientific disciplines –  the science about other people in other times. Since the “ethnographic present” has remained an important frame of reference for archaeological investigation, the idea of savage man has been directing archaeological interpretations of the culturally and chronologically most distant European pasts. The aim of the paper is to reconsider the mechanisms by which the humanities, applying the myth of savage man, enforce the modern European identity as opposed to the Others in space and time. The ideas of savage man will be explored in the context of Late Mediaeval and early modern societies, as the means for interpretation of identities in the past. After the postcolonial critique, this approach offers the model for understanding the ways in which communities in the past thought their own identities as opposed to imagined (non)humanity, but also how these imagined constructs influenced certain social practices recognizable in the archaeological record.
The Gordian Knot of Interpretation: Roman written sources, the idea of socio-cultural evolution and the concept of Romanization
Authors: D. Mihajlović Vladimir
Published: May 2019

In the Roman Empire, under the Greek influences, authors shared the idea of “the degree of humanity”, according to which the Romans formed value judgements about the “barbarian” societies. The framework of reference was constituted by the Roman society itself, taken as superior and predestined as the centre of the known world. The criteria for comparison were based upon the natural and climatic environment, socio-political organization, economy, religion, ways of life, warfare, marital practices, certain kinds of material culture and cultural practices in general. According to this view, the Mediterranean societies were “the most human”, and the level of humanity declined in direct relation to the geographical remoteness and other differences as compared to the centre. Although these speculations were not organized into a unified interpretive framework, like the modern social theories, they nevertheless were implicit assumptions of the Roman elite. This „naive“ or “common-sense anthropology” has had a strong impact on the formation of the premises of the modern anthropological theories, due to the general role of the ancient written sources in the processes of knowledge formation in modern Europe. It is therefore possible to assume that the ancient ideas, along with the later ones, played an important role in the shaping of the postulates of the early theory of socio-cultural evolution – the implicit base of interpretation of human societies during the 19th century. Consequently, the written sources have played a double role in the processes of formation of the concept of Romanization – directly, as well as through socio-cultural evolution, onto which the concept itself relied. In this way, the prejudices stemming from the discourse of Romanization gained the air of scientific interpretations, verified by two seemingly independent reference systems.
A Different Guest Worker Story: Roma Guest Workers – a Transnational Minority in Transmigration
Authors: Banić Grubišić Ana
Published: May 2019

The paper considers the ambiguity of the term ‘guest worker’, based on the example of economic migrants who belong to the Roma population. Over the last fifty years, members of the Roma minority have migrated to Western European countries for different reasons (economic, political and social reasons), and there is no official data on the precise number of Roma who have migrated abroad, whether permanently or temporarily. It is possible to establish a number of categories of Roma immigrants who reside permanently or temporarily in Western European countries. These are: the so-called “classic guest workers” who, through legal or illegal means went to work abroad in the 60’s and 70’s, and mostly settled permanently in the host countries; Roma refugees from Kosovo and/or asylum seekers who left the country during the wars in the 90’s, and who were returned to Serbia after the signing of the Readmission treaty; and those Roma who represent occasional economic migrants: people who, after Serbia was put on the white Schengen list (the liberalization of the visa policy for citizens of Serbia), spend three months at a time working abroad. Even though these three categories of Roma workers have different reasons for migrating from and returning to Serbia, the majority of the population perceives them as a unified, distinct whole – as guest workers. The paper is the result of fieldwork conducted in South-Eastern Serbia, in the village of Minicevo.
Inner Otherness as a Source of Fear: Elements of Horror in Balkan Travelogues
Authors: Lazarević Radak Sanja
Published: May 2019

Travel fiction has created numerous Others, assigning them an ontologically unstable status, while the traditional travelogue spread a fear of the dark interior of Europe, presenting images of daily political strife, assassinations, wars and uprisings. Just like the Gothic novel, which entertained its readers with images of ruins and gloomy structures in Eastern Europe, the travelogue spread a fear of the Balkans through Europe, depicting the Balkans as a place that could pose a threat to the entire continent. While enjoying the mysterious terror of the Gothic novel, Europe also derived a kind of pleasure from the shocking images that were to be found in travelogues from the Balkans. The paper re-examines the elasticity of the boundaries of the travelogue genre, and identifies convenient transformations of certain parts of the travelogue into text aimed at inspiring terror, shocking and appalling its readers. The transformations show that it is impossible to draw a strict boundary between travel fiction and travelogues, and at the same time reveal the hidden discourse used by both genres. The parallel presence of awareness of the geographic identity of the Balkans as European, and of the aspiration to depict them as the strange inner Otherness of Europe, is accompanied by the production of terrifying images. Although these images cannot be viewed solely as a threat of "reverse colonization", the assumption that hybridity is the basis on which the terrifying nature of the Balkans is produced is re-examined. The travelogue chapters, sections and illustrations assume the features of horror, particularly body horror, revealing Europe’s fear of the possibility of the Orient infiltrating the "body of the Occident", or of the possibility of the latter being infected by elements of "alien" i.e. Oriental culture.
Hypophosphatemia and refeeding syndrome in the resumption of nutrition in critical care patients (review)
Authors: Yaroshetskiy A. I. , Konanykhin Vasily D. , Stepanova S. O. , Rezepov N. A.
Published: May 2019

Refeeding syndrome is a life-threatening condition that occurs when nutrition is restarted in patients with initial malnutrition. For the first time refeeding syndrome was described more than 70 years ago but it still has not been studied enough. The pathophysiology of refeeding syndrome is based on severe electrolyte and metabolic disorders caused by the restoration of nutrition with an initial deficiency of phosphorus, potassium, magnesium which lead to organ failure. Hypophosphatemia is the main feature of the refeeding syndrome while in ICU patients there are many other causes of hypophosphatemia which complicates diagnostics. Most studies on refeeding syndrome have been conducted among patients with anorexia nervosa. In ICU refeeding hypophosphatemia occurs in about 34 % of cases but until recently all guidelines for the management of this condition have been extrapolated from the practice of treatment anorexia nervosa and were based on expert opinion. Several major studies have proven the effectiveness of a hypocaloric feeding during refeeding syndrome in critically ill patients recently.
This review is devoted to the problem of refeeding syndrome in patients with anorexia nervosa and critical care patients, differential diagnostics and treatment approaches for this condition.
Immigration Discourse in the British Press: Peculiarities of Construction
Authors: Matytsina M. S.
Published: May 2019

The present research features immigration discourse published in the Daily Mail. The author believes immigration discourse to be a consequence of the so-called Arab Spring of 2011. The paper describes some peculiarities of the discourse related to the events of 2011, its semantic indicators, and some particular examples. According to the critical discourse analysis, discourse is a form of social interaction, which makes it possible to clarify how ideology sets the formatting rules of discourse and determines its content. The relevance of the study is due to the growing scientific interest to the phenomenon of political discourse and its various aspects. The research revealed non-politicized terminology that represents immigrants as helpless, desperate victims, who are described with the help of "humanitarian" concepts when it goes about immigration control measures. However, the humanization and victimization of immigrants act as a justification for the measures taken to combat "illegal" immigration and the "humanitarian rescue" of citizens in danger.
Can vascular pathology in cerebral and coronary fields predict peripheral artery disease in a cohort of diabetic patients?
Authors: Chima Kamran K , Butt Ambreen , Masud Faisal , Saulat Bilal
Published: May 2019

Objective: To find out whether peripheral artery disease followed the same pattern, set of risk factors and indicators as macro vascular disease in the coronary arteries and cerebral arteries disease. Study design: This was a randomized cross sectional retrospective analysis. Place and duration: Study was carried out at The Diabetes Management Center at The Services Hospital Lahore, during June 1999 to June 2001. Patients and methods: A total of 580 patients were selected from the diabetic data base that had absent pulsations in the any of the four arteries of the lower limbs. Another set of 580 diabetics with presence of pulsations in all the arteries of the lower and upper limbs was randomly selected to match the cases. Results: Diabetics with peripheral vascular disease had a significant positive history of past CVA and past MI. Conclusion: Presence of peripheral vascular disease is significantly associated with presence of history of past CVA and past MI, raised systolic BP, diastolic BP, and mean BP and increased proteinurea.
Rectal Carcinoma, Mayo Hospital Experience
Authors: Chaudhry Zulfiqar A , Khan Farid Ahmad , Tarrar Khuda Dad , Akhtar Salman , Khan Shamim Ahmad , Ahmad Waseem
Published: May 2019

For patients having rectal carcinoma, resection offers the only chance of cure. The approach to operation is influenced by the finding at sigmoidoscopy, degree of fixity of the growth as assessed by rectal examination and the histology of the tumor. In the study different operative option according to the site of tumor and demographic aspect of the rectal carcinoma in local community were studied. It is a prospective study carried out at Mayo Hospital, Lahore Pakistan to assist in the development of the management guideline. In this study, 50 patients with new diagnosis of carcinoma rectum were included. Out of the 50 patients 44% had tumor of the upper rectum 16% in the middle and 40% in the lower rectum. In 96% of the cases histology was adenocarcinoma and 2% each for melanoma and lymphoma. Resection of the primary disease in 92% of the cases, 20% of the cases presented with acute obstruction and 4% of the cases were inoperable. Curative resection was possible in 80% of the cases, palliation was achieved in 12% cases and 4% of the cases deemed inoperable at the time of operation. Incidence of rectal carcinoma is higher in younger age group being < 40 and resection of the primary tumor is the cure in early cases.
Lateral Internal Sphincterotomy for Chronic Anal Fissure under local anesthesia as a Day Case Surgery
Authors: Siddique Tariq , Khan Sadaqat Ali , Rehman Madeha , Islam Haroon Rafiul , Ahmad Waseem
Published: May 2019

This prospective study was carried out in East Surgical unit, Mayo Hospital, Lahore for the period of two years from July 2001 to July 2002 on outpatient basis. Total of 50 patients aged between 20-50 years fulfilled the criteria of day case surgery i.e., health and social criteria (ASAI&II), only those were included in the study. The objectives were to evaluate the role of lateral sphicnterotomy under local anaesthesia as a day case surgery, considerable cost to patient and hospital, less morbidity and high patient acceptance. Thirty three patients (66%) were male and 17(34%) were female. Male to female ratio was about 2:1. Thirty nine patients (78%) presented with posterior anal fissure and 11 patients (12%) with anterior anal fissure. All patients operated under local anaesthesia as day case. Immediate relief from pain and painless first bowel movements was accomplished in 49(98%) of patients. No morbidity was observed. Postoperative complications were observed in 4 patients (8%) that resolved with conservative management. The patient acceptance was high (94%).
El impacto ambiental de los residuos de promoción electoral en Ecuador: caso de estudio de las lonas publicitarias
Authors: Arichábala Martínez Hellen
Published: May 2019

La gestión deficiente de los desechos sólidos es una amenaza inminente para el ambiente y la salud humana. Dentro de esta categoría se enmarcan residuos como la lona plástica publicitaria usada durante campañas electorales con el fin de promocionar organizaciones y candidatos políticos. Actualmente, en Ecuador no existe legislación que concierna a la regulación de la generación y gestión de este material publicitario electoral. Por lo tanto, la intención de la presente investigación es proponer un plan de gestión de las lonas de promoción electoral. Consecuentemente, se realizó un diagnóstico donde se identificó que el último periodo electoral generó aproximadamente 31,2 toneladas de este material, del cual se desconoce su destino final. Se realizó una breve descripción de los impactos ambientales que este producto puede ocasionar si no es atendido con la importancia que se requiere por parte de las autoridades. Finalmente, se proponen las estrategias aplicables para este problema.
Alpha Adducin (ADD1) Gene Polymorphism and New Onset of Diabetes Under the Influence of Selective Antihypertensive Therapy in Essential Hypertension
Authors: Gupta Sumeet , Jhawat Vikas , Agarwal Bimal Kumar , Roy Partha , Saini Vipin
Published: May 2019

Background:

Different antihypertensive therapies (especially diuretics) are reported to
induce the new onset of diabetes in some hypertensive patients. α-adducin-1 (ADD1) gene is salt
sensitive gene which has its role in etiology of hypertension via salt sensitivity. Therefore, the
G460T polymorphism of ADD1 gene may be associated with new onset of diabetes under the influence
of diuretic and other antihypertensive therapies.

Aim:

To assess the correlation between genetic polymorphism (ADD1 G460T polymorphism) and
glycaemic disturbance under influence of diuretic and other antihypertensive drug therapies.

Materials and Methods::

We recruited study subjects, 270 normotensive as control (150 male and
120 females), 270 hypertensive patients (95 male and 175 females) and 240 hypertensive with new
onset of diabetes patients (80 male and 160 females). All study samples were genotyped for ADD1
polymorphic alleles and analyzed the relationship between different genotypes with respect to anthropometric
and clinical parameters along with drug therapies.

Results:

Clinical and anthropometric parameters (such as age, SBP, DBP, FBG, height, weight,
WC, HP, W/H ratio, and BMI) of study population were found highly statistically significant
(p<0.05) at base value. Further, genotype wise comparison of all the above parameters revealed
most of them as non-significant (p>0.05). Whereas, comparison between genotype and different
antihypertensive drug therapy of hypertensive patients, specifically, diuretic therapy as mono in
male (p=0.0227) and female (p=0.0292) and in combination with BBs in both male (p=0.0023) and
female (p=0.0079) revealed a higher FBG level in variant T allele. In case of hypertensive with new
onset of diabetes patients, only female population showed a slightly statistically significant
(p=0.0413) difference in FBG level with diuretic mono therapy. Other antihypertensive drug therapies
were safe and effective either as mono or in combination therapy.

Discussion:

Anthropometric parameters may be the indicative factors for hypertension and diabetes.
Variant T allele of ADD1 gene may be considered as the risk factor for the development of
diabetes in hypertensive patients. Diuretics as mono therapy and in combination with BBs may be
considered as the risk factor for new onset of diabetes in EH patients carrying variant T allele (either
as TG or TT).
Development of a cycle-accurate simulator of the Elbrus processor core memory subsystem
Authors: Znamenskiy D. V. , Kutsevol V. N.
Published: May 2019

Increasing complexity of modern microprocessors, combined with semiconductor technology progress slowdown, make a further increase in performance more difficult. Under these circumstances, the relevance of the performance estimations of prospective microprocessors by dint of cycle-accurate simulation prior to their production in silicon is of growing importance. The approach to implementation of cycle-accurate simulator of core memory subsystem for Elbrus architecture, controlled by the existing functional simulator of this architecture, is presented herein. The method for validation of a cycleaccurate simulator by comparison with modeling of the RTL description of the prospective microprocessor is considered. The data on the speed of the cycle-accurate simulator and the main optimization methods, which were used to achieve acceptable performance, are presented. The preliminary estimates of the impact on the performance of some changes in the prospective processor core, including the cache access latency and hardware support for virtualization, obtained with the help of the cycle-accurate simulator are given. These assessments are important for making architectural decisions when designing the prospective Elbrus architecture processors.
A interseccionalidade de gênero, raça e classe em livros didáticos de EJA
Authors: Silva Márcia Alves da , Pinheiro Renata Kabke
Published: May 2019

Esta escrita apresenta algumas análises que fazem parte de uma pesquisa maior. Aqui são apresentadas análises de alguns livros pertencentes a uma coleção de livros didáticos voltada à educação de jovens e adultos nos anos finais do Ensino Fundamental. Essa coleção foi aprovada pelo Plano Nacional do Livro Didático (PNLD) e indicada para os anos 2014, 2015 e 2016. Em um primeiro momento, o texto traz um pequeno histórico dos programas de livros didáticos no país para, em um segundo momento, trazer a abordagem dos livros analisados. A intenção é problematizar as representações de gênero que os livros didáticos carregam, compreendendo gênero na sua interseccionalidade com raça e classe social. Em nossa investigação, é possível perceber que, mesmo com os avanços na legislação sobre o tema e da política de avaliação dos livros didáticos, implementada já há algum tempo, e ainda que se percebam avanços no que se refere ao combate à discriminação de gênero, raça e classe, persistem abordagens conservadoras e discriminatórias, mesmo que de forma bastante sutil, o que demonstra a naturalização de desigualdades sociais.
Public Response to Privatization of Healthcare Services in Saudi Arabia on Twitter (Preprint)
Authors: Alghamdi Abdulrahman , Alsaywid Basim , Abumelha Khalid , Bajammal Sohail , Manlangit Jr Juan
Published: May 2019

BACKGROUND

The Saudi government has been providing free medical care for all Saudis in public healthcare facilities, with the Ministry of Health being the major financing, operating, and supervising body. In July 2017, the Saudi government approved privatization of healthcare services.

OBJECTIVE

This study aimed to assess public reactions to this reform that have been shared on Twitter.

METHODS

All tweets that contained the hashtag “خصخصة_الصحة#” [i.e., #Healthcare_Privatization] between 9th and 16th July 2017 were collected. Manual content analysis of the tweets was carried out to identify sentiments, types of sources of the tweets and the general theme of each tweet. Association between the types of sources and sentiments delivered was tested using chi-square test.

RESULTS

Out of 12,430 tweets collected, 2,119 met the inclusion criteria and were included in the final analysis. Most tweets delivered neutral or undetermined sentiments [37.4%], followed by positive [35.2%] and then negative [27.4%] sentiments. Each tweet has been assigned to one out of nine themes that best fits. The most common theme of the tweets was ‘supportive and explanatory’ [24.6%] then ‘unsupportive and/or expecting failure’ [16.3%]. The majority of contributors were members of the public [85.1%] and the clinical and non-clinical healthcare workers [10.1%]. There was a significant association between the type of the source and the sentiments delivered 2 [6, N = 1740] = 82.1, P-value <0.0001]

CONCLUSIONS

Our study has shown that Twitter data represents a possible rich source of information to be studied by decision makers to evaluate public responses to major reforms in healthcare systems worldwide. Studying such data provides an insight into common concerns and misunderstandings to be addressed.
Hazard identification, risk assesment and risk control serta penerapan risk mapping pada rumah sakit hewan Prof. Soeparwi Universitas Gadjah Mada
Authors: Pertiwi Pertiwi , Nurhantari Yudha , Budihardjo Santosa
Published: May 2019

Hazard identification, risk assesment and risk control and the application of risk mapping at Hospital of the Animal Prof. Soeparwi Universitas Gadjah Mada Purpose: This research was held to analyze the work accident using HIRARC method and the applied of Risk Mapping at the hospital of the animal of Prof. Soeparwi Gadjah Mada University, Yogyakarta.Method: This research used descriptive qualitative research method. The qualitative method used to describe the condition, assess, and to recognize the work accident analysis. The data used was grabbed from Hazard Identification Risk Assessment and Risk Control (HIRARC) method and questionnaire.Results: Hazard identification used HIRARC method at the hospital of the animal of Prof. Soeparwi Gadjah Mada University was about 198. The work hazard commonly includes physical hazard, chemistry, biologist, ergonomics, and psychosocial. The risk assessment which held denoted that there were 61 low risks, 108 medium risks, and 15 high risks. The recommendations of risk restraint that can be given were technician control, administrative, and the use of personal protective equipment (PPE).Conclusion: HIRARC method had been applied at the hospital of animal of Prof. Soeparwi with the result to that grooming unit was high risk work place, assessed with risk mapping. The risk was from animal contact phisically.
Pelatihan “INTERAKTIF” Meningkatkan Empati Guru BK
Authors: Harisah Risa , Ramdhani Neila
Published: May 2019

Abstract. The “INTERAKTIF” training was compiled to increase the empathy of school counselor in assisting their students. The “INTERAKTIF” module consist of emotional intelligence and therapeutic communication theory. The research was conducted by untreated control group design method with dependent pretest and posttest samples, which include experimental group and control group. Participants in this reseach consist of 46 junior high school counselors in Yogyakarta. Statistical analysis result using Mixed ANOVA showed that empathy level on experiment group significantly differ from control group (F=4,805, p = 0,034). The final result show that the “INTERAKTIF” training effective in increasing the junior high school counselor’s empathy in Yogyakarta.   Keywords : empathy; emotional intelligence; therapeutic communication
Water Use Efficiency in Vertical Cropping System with Volcanic Ash Media by Using Biochar and Urban Waste Compost Fertilizer as Soil Amendement
Authors: Nitisapto Mulyono , Maas Azwar , Purwanto Benito Heru , Sudira Putu
Published: May 2019

Applying volcanic ash as planting media has to cope with several constrains: it quickly became sediment and hardened when exposed to water. One of the efforts to improve its physical condition is by utilizing biochar, which is one of amendment materials that can improve the soil quality. This study used vertical column container made from PVC to enable vertical plant arrangement. Volcanic ash requires additional nutrient intake from organic fertilizer such as urban waste compost. The objective of this study was to identify the proper dose combination of volcanic ash, biochar, urban waste compost fertilizer and column population per m2 to sustain the growth of curly lettuce in vertical cropping system, as well as the water use efficiency. This study was designed by using the Completely Randomized Design (CRD) Factorial with three factors. The first, second and third factors consisted of Biochar M1, M2 and M3 (25; 33; and 50 %), compost fertilizer doses of K1, K2, and K3 (25; 33; and 50 %), and column density of P1, P2 and P3 (4 columns/m2, 3 columns/m2 and 2 columns/m2), respectively. The total combination was 3 x 3 x 3 and each was repeated 3 times. Resulted data of this study consisted of growth and crops and analyzed by using the Analysis of Variance and continued with the HSD Tukey 5% Test (Honest significant deference). The water use efficiency (g/kg) can be formulated as the production of dry material per total water during the cultivation season (g/kg). Results of this study showed the highest fresh consumption result was obtained from treatment M3K3 in 556 g/column (comparison of volcanic ash, charcoal husk and compost = 25 : 25 : 50 %) and the best water-use efficiency was 2.30 g/kg.
CIE L*a*b* Color Space Based Vegetation Indices Derived from Unmanned Aerial Vehicle Captured Images for Chlorophyll and Nitrogen Content Estimation of Tea (Camellia sinensis L. Kuntze) Leaves
Authors: Wahono Wahono , Indradewa Didik , Sunarminto Bambang Hendro , Haryono Eko , Prajitno Djoko
Published: May 2019

A lot of digital image techniques to assess crop agronomic character have been developed.  Most of those techniques are based on non-visible light equiped cameras, such as infared wavelengths. This research was aimed to examine the use of commercial digital camera with sensor range in visible light spectrum using CIE L*a*b* color space to estimate chlorophyll and nitrogen content of tea leaf.  Data was collected from an experiment of nitrogen dossage levels on 3 years after prunning tea crops.  The result shows that Lb* Difference Simple Index (LI), a*b* Difference Simple Index (AI), and  a* Vegetation Index (VIA) can be used to estimate tea leaf chlorophyll and nitrogen content.  The relationship between VIA and tea leaf nitrogen content was defined on linear equation y = 1.8382x2 - 0.3099x + 3.0658 with determinant coefficient R² = 0.71.
Pedogenesis of Mt. Sumbing Volcanic Ash above The Alteration Clay Layer in The Formation of Landslide Susceptible Soils in Bompon Sub-Watershed
Authors: Wida Waode Asryanti , Maas Azwar , Sartohadi Junun
Published: May 2019

Numerous researches on landslides have been carried out by many researches. However, studies on soil physical properties related to landslides potential in volcanic area are still rare. The objective of this study was to examine the effect of soil physical properties on landslides potential. To collect the soil sample, sampling area method was applied. The soil type used in this study was the residual soil. The values of clay liquid limit, plasticity limit, plasticity index, water content, COLE index were used to measure the physical properties of the soil. Organic material was used as the supporting data. The results showed that the soil in the command area showed high value of clay which exceeded 50%. Such high level conditions in each profile affect the liquid limit; plasticity limit, plasticity index, water content, COLE index and organic material. Based on the results, it can be concluded that residual soils with significantly high clay values illustrated the risk of landslide fields formation in Bompon sub-watershed. The clay soil layer was the controlled factor of soil movement.
Pemanfaatan sekolah sebagai sarana pencegahan obesitas sejak dini pada remaja
Authors: Muhammad Harry Freitag Luglio
Published: May 2019

Obesity among adolescents is a new nutritional problem in Indonesia. This is not only associated with increased risk for obesity in later life but also increased the risk for cardiovascular diseases, type 2 diabetes mellitus, hypertension, and other non-communicable diseases. Therefore an effective and integrated obesity prevention program is highly warranted. There are several community-based programs for obesity prevention that have been developed in the past few decades and school-based activity is one of the potential programs that could be implemented in the Indonesian setting. School is a strategic location for obesity prevention programs in the adolescents because school is the place where most of the adolescents spending their time outside their home. In addition, a school also a centralized community where health and nutrition promotion programs can be done at the same time. In 2012, the Indonesian Ministry of Health published a guidebook on the prevention and treatment of adolescents with obesity at school. However, this guideline only focusing on the role of health workers at puskesmas level and not detailing the role of the school in managing obesity prevention program. Thus, this review was made to provide an alternative solution for obesity prevention in adolescent via programs that can be done at school. Author aimed this review for school managers, puskesmas health workers, the local department of health, researcher and non-government organization that has the concern regarding adolescents health especially in relation to nutrition. This review can be a foundation for the development and implementation of school-based obesity prevention programs as well as a reference for the development of school policy.
Authors: Prakoso Aryo , Wardhaningrum Oktaviani Ari
Published: May 2019

Kesilir Village, Wuluhan District, Jember Regency is one of the villages that is expected to have village independence. The main program for developing cooperation between Universitas Jember and local villages through thematic KKN programs is the development of tourism villages and prosperous entrepreneurs. One of the independent businesses in this village is Usaha Cipta Mandiri, a home industry that is engaged in furniture manufacturing. The products produced are heterogeneous and can be tailored to the needs of consumers. The products produced are furniture, chairs, tables, cabinets, door leaves, shutters and so on. Usaha Cipta Mandiri serves consumers from around the city in the Besuki Residency. Even though the entrepreneur has the tagline What You Order We Do, in accordance with the wishes of the client, this business still has a fundamental weakness in its business, namely a cost management system that is not measured and recorded. Solutions offered by the above problems, through the collaboration of the University of Jember service team and the involvement of students with Cipta Usaha Mandiri partners, by designing accounting records in a simple way using Microsoft Excel program. The target of this activity is accounting software manufacturing with Microsoft Excel platform.

Keywords: independence, production costs, manufacturing accounting
El comercio entre Guatemala y Perú y el debate de las bebidas embriagantes
Authors: Mora de Tovar Gilma
Published: May 2019

El Reino de Guatemala fue durante el período colonial uno de los territorios que se podría calificar de marginal en el contexto del Imperio Español. La ausencia de metales preciosos, como el oro y la plata, determinó económica y políticamente la importancia de esta región. Al no disponer de tales recursos, el Reino de Guatemala basó su economía en la comercialización de brea, añil, tintas, cacao, sebo y ganados que fueron intercambiados por vinos, aceites y vinagres del Perú. Al ser pobre en metales preciosos esta región no despertó particular interés en la gran masa migratoria de colonos peninsulares. Como la riqueza fundamental era la fuerza de trabajo de los indígenas, fue repartida en encomiendas, lo que permitió a los colonos españoles incorporar la fuerza de trabajo a la producción de bienes para el consumo interno y para el intercambio con otras regiones coloniales de América. Además, mediante esta institución, los peninsulares disfrutaron del tributo que estaban obligados a pagar los naturales como reconocimiento de vasallaje
Intransigencia y nación. El discurso de Ezequiel Moreno y Nicolás Casas, primeros vicarios apostólicos del Casanare
Authors: Cortés Guerrero José David
Published: May 2019

Los dos primeros vicarios apostólicos del Casanare llegaron a Colombia procedentes de España con el objetivo de establecer la misión religiosa en el territorio llanero. Luego, se encargaron del vicariato, cuando éste fue separado de la diócesis de Tunja (1893) y constituido en unidad eclesiástica autónoma. Lo interesante es que el discurso empleado por Ezequiel Moreno y Nicolás Casas quien lo elaboró cuando realizaba su misión evangelizadora en Casanare, territorio poco poblado y donde los grandes debates políticos, económicos y sociales eran insípidos o inexistentes, está inscrito en el debate europeo de la intransigencia católica contra el mundo liberal moderno y sus ideas.
Colonos, empresarios y vagos: experiencias fronterizas en el caribe en la primera mitad del siglo XIX
Authors: Ramos Peñuela Aristides
Published: May 2019

Las transformaciones del universo rural colombiano en el siglo XIX fueron en gran parte el resultado de migraciones, desde los núcleos poblacionales andinos, hacia las tierras de vertiente de las fronteras. Espontáneos unos y dirigidos otros, ambos movimientos contribuyeron a la consolidación de nuevos territorios y a la incorporación de tierras baldías para las economías regionales y nacional. La expansión hacia el bosque húmedo tropical en su primera fasefue un proceso predominantemente dirigido, donde listado y empresarios centraron sus intereses económicos en los recursos forestales propios de aquellas zonas, que como la quina, el caucho y la tagua, estaban siendo demandadas por la economía mundial.