bluuebunny/crossref_metadata_2025 huggingface dataset:
Haplotype analysis and linkage disequilibrium of BRCA genes in glioblastoma: Impact on treatment response
Authors: Khalifa Mohamed K. , Nageeb Amira M. , Mohamed Magdy M. , Arab Lobna R. Ezz El , Swellam Menha
Published: February 2024

Glioblastoma (GBM) is an aggressive primary brain tumor prevalent in adults, characterized as a common malignant neoplasm of the human central nervous system with the worst survival rate among cancers. Treatment of GBM involves the addition of the alkylating agent temozolomide (TMZ) to radiotherapy, which improves overall survival by preventing replication through alkyl group-mediated DNA cross-linking. Genes related to homologous recombination (HR)-dependent DNA repair, such as the breast cancer susceptibility genes (BRCA), specifically BRCA1 or BRCA2, contribute to cellular resistance to alkylating agents. We aimed to perform a haplotype-based study on the frequencies of BRCA1 mutations in GBM patients compared to healthy individuals and investigate their linkage disequilibrium (LD) with the data population. Blood samples from GBM patients (n = 15) and healthy controls (n = 25) were sequenced using the Ion Torrent PGM platform to identify the BRCA1 mutation. Subsequently, the reported variants were submitted to the LDlink tool for haplotype analysis, and their association with treatment response was assessed. Our results revealed that the BRCA1 haplotype block consisted of seven SNPs, whose frequencies were reported with strong LD when compared to all available population data. This block was found to be represented by eight haplotypes. Five of these haplotypes were previously reported (four haplotypes were commonly reported, and one was rare), while the remaining three haplotypes were newly reported in this study. The relationship between newly reported haplotypes and response to treatment revealed that patients with these haplotypes responded to TMZ either as a complete or partial response. In addition, one haplotype in the heterozygote form was reported in the control case. In conclusion, haplotype analysis for BRCA genes in GBM cases can aid in predicting treatment responses and identifying cancer risk factors in individuals.
Genetic Variability of Service Tree (Sorbus domestica L.) in the Hungarian Middle Mountains : Based on cpDNA Analysis in Two Regions
Authors: Nyári László
Published: February 2024

A genetic inventory was conducted at maternally inherited chloroplast DNA (cpDNA) gene loci of 196 adult service trees (S. domestica). The sampled trees represent autochthonous collectives/populations originating from 2 distant regions, from contrasting habitats, a forested area (eastern part of the Dunazug Mountains) and cultured habitats (Zemplén Mountains), respectively. Strong intrapopulation variation was observed; percentages of molecular variance were: between regions 27%, among populations/regions 6%, within populations 67%. Considering all samples, the major part of total diversity (ht = 0.752) was contributed by intrapopulation diversity (hs = 0.583). Species diversity was represented differently in individual populations. E.g. the population Kácsárd contains only one haplotype: the doubtless sign of local human cultivation. The population Buda Hills has an average differentiation considering the whole sampled material but the highest when evaluating the region north from Budapest separately. That points to the dispersion after an introduction event, probably parallel to adaptive radiation under selection influence. In the study genetically polymorphic populations containing unique haplotypes were detected, providing important information for forest management, gene conservation and nature protection activities. The described work is part of ex situ gene conservation projects of the species in Hungary.
Quality and Assortment Structure of Beech High Forests in Serbia
Authors: Koprivica Miloš , Matović Bratislav , Čokeša Vlado , Stajić Snežana
Published: February 2024

The paper presents research results on quality and assortment structure of uneven-aged beech high forests in Central Serbia. Eleven representative stands of submontane beech forest (Fagenion moesiacae submontanum B. Jov. 1976 ) and montane beech forest (Fagenion moesiacae montanum B. Jov. 1976) were selected. Their altitude ranges from 450 m to 1350 m. Site class ranges from I/II to III/IV, canopy closure from 0.7 to 0.9 and volume from 290 m3/ha to 522 m3/ha. Total area of the stands is 241.9 ha. Sample plots of 500 m2 were established in a systematic grid of 100 x 100 m. From silvicultural aspect, 16% of the standing volume (384 m3/ha) is class one, 39% is class two and 45% is class three. From the aspect of forest utilization 37% of the volume is class one, 34% is class two, 19% is class three, and 10% is class four. In the assortment structure of the average stand volume, industrial wood accounts for 42%, cordwood 48% and waste 10%. It has been concluded that beech high forests in Serbia have unfavourable quality and assortment structure. This situation should be improved in future by taking adequate management measures.
Artificial intelligence: Applications in critical care gastroenterology
Authors: Juneja Deven
Published: February 2024

Gastrointestinal (GI) complications frequently necessitate intensive care unit (ICU) admission. Additionally, critically ill patients also develop GI complications requiring further diagnostic and therapeutic interventions. However, these patients form a vulnerable group, who are at risk for developing side effects and complications. Every effort must be made to reduce invasiveness and ensure safety of interventions in ICU patients. Artificial intelligence (AI) is a rapidly evolving technology with several potential applications in healthcare settings. ICUs produce a large amount of data, which may be employed for creation of AI algorithms, and provide a lucrative opportunity for application of AI. However, the current role of AI in these patients remains limited due to lack of large-scale trials comparing the efficacy of AI with the accepted standards of care.
Pengaruh Inventory Intensity, Thin Capitalization, Current Ratio dan Pemeriksaan Pajak Terhadap Tax Avoidance
Authors: Muhammad Setiawan  , Monica Rahardian Ary Helmina  , Novita Weningtyas Respati
Published: February 2024

This study aims to obtain empirical evidence regarding the effect of inventory intensity, thin  capitalization, current ratio and tax inpection on tax avoidance. The type of this research is associative research with a quantitative approach. The data used in this study is  secondary data where the data is obtained from KPP Madya Banjarmasin. The dependent variable in this study is tax avoidance and the independent variable in this study is inventory intensity, thin  capitalization, current ratio and tax inpection. The sample of this research is 81 large trading companies registered in KPP Madya Banjarmasin  that have been selected using predetermined criteria. The analysis technique used in this research is multiple linier regression test. The results of this study indicate that inventory intensity, and tax inpection has positively affects on tax avoidance. Meanwhile, the current ratio does not affect tax avoidance
Control of Robot Motion in Radial Mass Density Field
Authors: Novakovic Branko , Kasac Dubravko Majetic Josip , Brezak Danko
Published: February 2024

T In this article, a new approach to control of robot motion in the radial mass density field is presented. This field is between the maximal and the minimal radial mass density values. Between these two limited values, one can use n points (n = 1, 2, . . . nmax) that can be included in the related algorithm for control of the robot motion. The number of the points nstep can be calculated by using the relation nstep = nmax / nvar , where nvar is the control parameter. The radial mass density is maximal at the minimal gravitational radius and minimal at the maximal gravitational radius. This is valid for Planck scale and for the scales that are less or higher of that one. Using the ratio of Planck mass and Planck radius it is generated the energy conservation constant κ = 0.99993392118.
Equilibrium Solutions of a Modified SIR Model with Vaccination and Several Levels of Immunity
Authors: Guiaş Flavius
Published: February 2024

We consider a system of ordinary differential equations which extends the well-known SIR model for the dynamics of an epidemic. The main feature is that the population is divided in several subgroups according to their immunity level, which has as a consequence different infection rates. The maximum level of immunity can be achieved either by recovering from an infection, or by possible vaccination. We consider the cases that the vaccination rate is independent on the size of infected population, or that it depends also on this value by a power law. In addition, we assume that the immunity level can decay in time. The goal of this paper is to analyze the existence and uniqueness of equilibrium solutions, which can be either a trivial (disease-free) equilibrium, with no infections, or an endemic equilibrium, with a certain amount of infected individuals. Moreover, we give conditions for the local asymptotic stability of the unique trivial equilibrium solution. It will turn out that, if this is the case, then there exists no endemic equilibrium, which means that the epidemic can be eradicated, by arriving at herd immunity. On the other hand, if the trivial equilibrium is unstable, then we prove the existence of an endemic equilibrium which, under natural conditions, turns out to be unique. The stability of the endemic equilibrium remains still an open problem.
Data Mining from Knowledge Cases of COVID-19
Authors: Evtimova-Gardair Mariya
Published: February 2024

A lot of articles were produced during the pandemic of COVID-19 and continue to be produced. The article proposes a system for diagnosis of COVID-19 disease. Also nowadays, the presentation of knowledge and the research for the reasoning algorithms are progressively improving in the domain of Artificial Intelligence. Besides these, distributed reasoning as a part of data mining has become a solution for the increasing everyday data amount. As a result, the paper proposes a case-based non-monotonic reasoner for uncertain and vague COVID-19 information that is appropriate for work with Big Data. Also, a COVID-19 knowledge base model is proposed. The reasoner implements rules for the distribution of the information that gives the possibility to work with Big data. The proposed reasoning algorithm is applied for COVID-19. It shows the implementation of the reasoner into the data mining system and the returned results from the system are evaluated. The results show that the system returns relatively high results concerning the other system for recommendation.
Additives in Edible Soy Protein Film Incorporation of Polysaccharides, Nano Polysaccharides, Vegetable Oils and Phenolic Additives in Edible Soy Protein Film
Authors: Kumar Rakesh
Published: February 2024

Soy protein isolate (SPI) is one such plant derived protein that holds significant potential for fabrication of edible films and packaging materials owing to its smooth, flexible and fair film forming abilities. However, native SPI suffers from several limitations such as poor water resistance, tensile strength, and susceptibility towards microbial attack. Many plants and animal derived compounds have been tried and tested to improve the material properties of these films. Incorporation of polysaccharides, nano polysaccharides, vegetable oils and polyphenolic compounds are explored to attain desirable properties in prepared films. Phenolic compounds are generally targeted to increase the tensile strength and resistance towards microbial attack as they possess rigid planar aromatic ring and hydroxyl groups that make them suitable candidate of choice. Polysaccharides or nanopolysaccharides and vegetable oils are reported to enhance the oxygen, carbon dioxide gas barrier properties of edible films that could delay putrefaction of packaged food items. Moreover, polyphenols and polysaccharide compound also exhibit bacteriostatic and bactericidal effect against S. aureus, L. monocytogenes and E. coli. This review paper summarizes the incorporation of polyphenolics, polysaccharides, nanopolysaccharides and vegetable oils in SPI films followed by their material and antibacterial characterization.
Panchkarma in Janpadodhwansa w.s.r. COVID-19 and Its Documentation from Ayurvedic Texts
Authors: . Anshul , Mehta Asish , . Saroj
Published: February 2024

COVID-19 has emerged as a public health crisis and has done caused a disaster at multiple -levels. Manual retrieval of ancient books of Ayurveda was carried out. In From an Ayurvedic point of view, its very difficult to correlate COVID-19 with Aayurvedic terminology, on the basis of causes, symptoms, and complications., Iit can be correlated with various diseases like Janpadodhwansha(~epidemic), Shwasa(respiratory disease), pranaavrit vata(subtype of vata that is seated in head), dushi-visha(~cumulative), jwara-sannipattika (~severe fever), vata-kaphaja jwar (fever) , shwasana (~pneumonia), Abhisangaj jwar ( ~fever caused by virus or evil spirit), majjadhatugata jwar (~vitiated regulatory factors are located in structural component of bone marrow ) &and kasa roga (coughing). Treatment in such conditions is mentioned as Panchkarma (~detoxification procedure) . The main goal in such type of condition is to remove avarana (overlapping) so that Vayu (air) returns to normal functioning. Five detoxification procedures were also reported to be effective against a broad spectrum of viruses, including human immunodeficiency virus, herpes viruses, etc. Ayurvedic detoxification procedures can add an additive effect in to the managing COVID-19 through multiple modules, like as prophylactic and, curative treatment. Implementation of suggested influence or mode of action probably come up with empirical discernment escalating the Ayurveda other than prophylactic medical management and system considering alike ailments.
Temel Biyokimya Özet Konular
Authors: Alayunt Naci Ömer
Published: February 2024

Çağımızda hızlı gelişen teknoloji ve bilim, beraberinde eğitim sistemi ile birlikte bilimsel düşünceninde güncel tutulmasını gerektirir. Eğitim hayatımda fazla sayıda kitap ve makale okumam ve girdiğim sınavlarda biyokimya kitaplarını derinlemesine incelemem bu kitabın yazılmasında bana ışık tutmuştur. Bu biyokimya kitabı temel ana başlıklar ve alt başlıklar halinde hazırlanmıştır. Sade bir dil kullanılarak okurun sıkılmaması için gereken özen eksiksiz gösterilmeye çalışılmıştır. Elektronik kaynakların günümüzde kitapların yerini almak için teknolojik atılımı ve bilgiye kolay erişilmesinde sıkça kullanılması, kitapların okunmasını azalttığı gibi hazıra alışma özelliğini beraberinde getirmiştir. Öğrenmede kitap okumanın ve yazarak çalışmanın büyüsüne inanan bir akademisyen olarak bilgi birikimi ve biyokimyanın esaslarını ele alarak hazırladığım bu kitabın, özet kaynak olarak genç nesiller tarafından okunacak bir el kitabı olmasını dilerim. Bu kitabın özellikle önlisans ve lisans eğitimlerinde öğrencilere katkı sağlayacağını düşünmekteyim.
Enfeksiyon Hastalıkları
Authors: Evik Güliz , Kızılyıldırım Suna , Akan Nazife , Ersöz Gülden , Külcü Didem , Öz Fatma Betül , Ataseven Bulun Mehtap , Kaynak Besime Ahu , Salman Filiz , Horasanlı Elif Şahin , Aktaş Demet , Erdem Yurdagül , Ertuğ Nurcan , Çavuşoğlu Esra , Çelik Fatma Tülin , Yurdakul Mine , Bayram Abiha Gül , Öztaş Duygu , Yalçın Saba
Published: February 2024

Enfeksiyonlara Ait Temel Özellikler
Güliz EVİK
Ali KAYA
Mikroorganizmalara Genel Bakış
Suna KIZILYILDIRIM
Enfeksiyon Hastalıklarında Tanı
Behire SANÇAR
Enfeksiyon Hastalıklarında Tedavi
Nazife AKAN
Akut Ateşli Hastaya Yaklaşım ve Bakım
Behire SANÇAR
Aynur ÇELİK
Enfeksiyon Hastalıklarında Korunma ve Kontrol
Gülden ERSÖZ
Hastane Enfeksiyonları ve Enfeksiyon Kontrolü
Gülden ERSÖZ
Asepsi - Antisepsi
Didem POLAT KÜLCÜ
Fatma Betül ÖZ
Özel Konakta Enfeksiyon Kontrolü
Mehtap ATASEVEN BULUN
Diş Hekimliğinde Enfeksiyon Kontrolü
Besime Ahu KAYNAK
Solunum Yolu Enfeksiyonları
Filiz SALMAN
Hematopoetik ve Lenforetiküler Sistem Enfeksiyonları
Elif Şahin HORASAN
Kardiyovasküler Enfeksiyonlar
Demet AKTAŞ
Gastrointestinal Sistem Enfeksiyonları
Fügen ÖZCANARSLAN
Döküntülü Enfeksiyonlar ve Çocukluk Çağı Aşıları
Yurdagül ERDEM
Deri ve Yumuşak Doku Enfeksiyonları
Şahinde CANBULAT
Kemik ve Eklem Enfeksiyonları
Nurcan ERTUĞ
Santral Sinir Sistemi Enfeksiyonları
Esra ÇAVUŞOĞLU
Fatma Tülin ÇELİK
Genitoüriner Sistem Enfeksiyonları
Mine YURDAKUL
Bildirimi Zorunlu Hastalıklar
Duygu ÖZTAŞ
Enfeksiyon Hastalıklarının Psikososyal Yönü
Saba YALÇIN
GÖÇ SOSYOLOJİSİ -Farklı Boyutlarıyla Göç-
Authors: Öztürk Ali , Erkan Ümmet , Nas Fethi , Özdemir Metlioğlu Seçil , Malkoç Enver Sinan , Saltık Ekrem , Solakumur Adem , Taş Zeki , Ünlü Yılmaz , Kul Murat , Yarcı Selman , Koçak Hüseyin , Çelik Ali
Published: February 2024

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İç Hastalıklarında Temel Semiyoloji
Authors: Oğuz İnan Başak , Kızmaz Muhammet , Avcı Gülru , Gamsız Tuğba Sevinç , İpek Yıldız , Gürsoy Vildan , Heybeli Hilal , Aykaş Fatma , Güven Alper Tuna , Kara Sonat Pınar , Badak Tolga Onur , Bilican Gülden , Gökmen Ersin , Ağır Hatice , Akkan Suzan Ayşegül , Kirli İsmail , Kul Ayşe Nilgün , Tazeoğlu Deniz , Ay Mehmet Emre , Bahadır Özgür , Çağır Büşra Betül , Sözışık Seçil , Can Mustafa , Algül Fatma Ebru , Gökgöz Durmaz Funda , Güllü Koca Tuba , Yeşiltepe Ali , Mete Yıldırım Aslıhan , Ergen Pınar , Yılmaz Karadağ Fatma , Akbay Nursel , Bilge Müge , Kaplan Efe Fatma , Yalım Sümeyra Alan , Öztop Nida , Beyaz Şengül , Yalın Kocamaz Gökçem , Yeşilova Aylia , Can Müçteba , Oral Ayşe Yeşim , Ay İbrahim Ethem , Akdoğan Müberra , Gamsız Tuğba Sevinç , Boz Gülşah , İpek Eyvaz Zekiye Pınar , Gencer Selman , Özden Yılmaz Ebru , Yılmaz Arda Şakir
Published: February 2024

Anamnez Alma Şema ve Özellikler
Başak OĞUZ İNAN
Hasta Şikayeti ve Kimlik Bilgisi
Muhammet KIZMAZ
Anamnez Alma
Gülru AVCI
Özgeçmiş
Tuğba Sevinç GAMSIZ
Soy Geçmiş
Yıldız İPEK
Sosyal Durum ve Alışkanlıklar
Vildan GÜRSOY
Kullandığı İlaçlar
Hilal HEYBELİ
Beden Fonksiyonları
Fatma AYKAŞ
Genel Durum Sorgusu
Alper Tuna GÜVEN
Solunum Sistemiyle İlgili Sorgu
Sonat Pınar KARA
Kardiyovasküler Sistemle İlgili Sorgu
Tolga Onur BADAK
Gastrointestinal Sistemle İlgili Sorgu
Gülden BİLİCAN
Üroloji’de Anamnez
Ersin GÖKMEN
Lokomotor Sistemle İlgili Sorgulama
Hatice AĞIR
Sinir Sistemi İle İlgili Sorgu
Ayşegül AKKAN SUZAN
Fizik Muayene Usulleri–İnspeksiyon
İsmail KIRLI
Fizik Muayene Usulleri (Palpasyon)
Ayşe Nilgün KUL
Perküsyon
Deniz TAZEOĞLU
Oskültasyon
Mehmet Emre AY
Metabolik Nedenlere Bağlı Karın Ağrıları
Özgür BAHADIR
Beslenme Durumunun Değerlendirilmesi
Büşra Betül ÇAĞIR
Boy ve Önemli Gelişim Hastalıkları (I)
Seçil ÖZIŞIK
Boy ve Önemli Gelişim Hastalıkları (II)
Mustafa CAN
Postür Muayenesi
Hatice AĞIR
Anormal Hareket Bozuklukları-I
Fatma Ebru ALGÜL
Anormal Hareket Bozuklukları-II
Fatma Ebru ALGÜL
Yürüyüş
Funda GÖKGÖZ DURMAZ
Konuşmanın Değerlendirilmesi ve Konuşma Bozuklukları
Tuba GÜLLÜ KOCA
Koku Alma
Ali YEŞİLTEPE
Ateş
Aslıhan METE YILDIRIM
Ateş ve Tipleri
Pınar ERGEN, Fatma YILMAZ KARADAĞ
Terleme
Nursel AKBAY
Tırnaklar (I)
 Müge BİLGE
Tırnaklar (II)
Fatma KAPLAN EFE
Epidermis, Dermis, Subkutan Doku
Sümeyra Alan YALIM
Primer Deri Lezyonları
Nida ÖZTOP
Sekonder Deri Lezyonları
Şengül BEYAZ
Derinin Muayenesi
Gökçem YALIN KOCAMAZ
Baş Muayenesi
Aylia YEŞİLOVA
Yüzün ve Saçın Muayenesi-Özel Hastalıklarda
Müçteba CAN
Göz Hastalıklarında Ön Segment Muayenesi
Ayşe Yeşim ORAL, İbrahim Ethem AY
Göz Hastalıklarında Arka Segment Muayenesi
Müberra AKDOĞAN, İbrahim Ethem AY
Burun Muayenesi
Tuğba Sevinç GAMSIZ
Dudakların Muayenesi
Gülşah BOZ
Kulaklar
Zekiye Pınar İPEK EYVAZ
Boyun Muayenesi, Boyun Damarlarının Muayenesi, Boyun Lenf Ganglionlarının Muayenesi, Trachea Muayenesi
Selman GENCER
Tiroid Muayenesi
Ebru ÖZDEN YILMAZ, Arda Şakir YILMAZ
A Sarcopenia na Terceira Idade e em Pessoas Obesos
Authors: De Sales Santiago Patrícia Rosany , Agrela Rodrigues Fabiano de Abreu
Published: February 2024

A sarcopenia é uma condição onde ocorre um distúrbio muscular esquelético progressivo  generalizado, ocorrendo a perda acelerada da massa e da função muscular.  Foi realizado um levantamento bibliográfico sobre a ocorrência da sarcopenia em pessoas idosas, uma  análise acerca das diversas dificuldades clínicas enfrentadas, assim como as formas de tratamentos comumente utilizadas para tratamento desta condição. Através da literatura é possível evidenciar as grandes dificuldades enfrentadas pelos pacientes acometidos desta condição, os pacientes enfrentam dificuldades motoras e de locomoção, o que pode implicar na saúde emocional dos mesmo , também são atingidos no âmbito cognitivo e na perda da força.
Análisis de las Tareas del Lenguaje Entrenado para la Comprensión y Generación de Textos ChatGPT en Instituciones de Educación Superior
Authors: Coloma Argüello Jessica Maribel , Carrillo Soto Stalin Chayanne , Espinoza Rojas Stalin Jeovanny
Published: February 2024

Este estudio se enfoca analizar las tareas del modelo de lenguaje entrenado para la comprensión y generación de textos ChatGPT en Instituciones de Educación Superior de la ciudad de Loja en el periodo académico abril - septiembre 2023, para llevar a cabo este análisis de tipo descriptivo, se adoptó un método deductivo con un enfoque cuantitativo, utilizando la técnica de encuestas como principal medio de recolección de datos y un cuestionario como instrumento principal; asimismo, la población de interés consistió en 253 docentes pertenecientes a dos institutos superiores tecnológicos y una universidad, todos de la ciudad de Loja en Ecuador, a quienes se encuestaron de manera presencial. Una vez analizados los datos obtenidos, se confirmó que el Instituto Superior Tecnológico del Estado registró el porcentaje más alto del 60,11%, en la primera categoría denominada "Análisis de datos y generación de código informático a través de instrucciones delimitadas", asimismo el Instituto Superior Tecnológico Particular obtuvo su porcentaje más alto del 31,48% en la misma categoría y finalmente la Universidad Particular destaca con un notable 58,15%, en la categoría de “Generación de textos coherentes y bien estructurados, abarcando diversos géneros narrativos y con distintos grados de extensión a partir de una instrucción inicial simple”.
La Adopción de las TIC como Factor del Comportamiento Innovador en Empresas del Vino del Valle de Guadalupe
Authors: Luna Andrade Andres Antonio , Peregrina Roque Felipe de Jesús , Luna Andrade Ricardo
Published: February 2024

Esta investigación analiza como la adopción del uso de TIC permite el Comportamiento innovador de las empresas del vino del Valle de Guadalupe, Baja California México. En este contexto, el estudio se centra en descubrir las relaciones causales entre el uso de las TIC y el comportamiento innovador, con la finalidad de contribuir al crecimiento sostenible y fortalecimiento de estas empresas en el sector vitivinícola de la región. Adopta un enfoque cuantitativo, es de tipo correlacional-causal con diseño no experimental transversal, ya que pretende que las observaciones se llevan a cabo en un momento o tiempo único. En lo que concierne a la selección de la muestra, fue no probabilística y se recolectaron datos mediante un cuestionario estructurado con 50 ítems, siendo aplicado a propietarios, directores, gerentes y administradores.  Aunque existen pocos estudios, se aprecian avances tecnológicos impulsando el comportamiento innovador en las empresas del vino de manera evidente. Todas las respuestas obtenidas y presentadas en este trabajo se utilizó el programa estadístico Software Stadistics Package for the Social Sciences (SPSS) con la versión 29 para generar las tablas de frecuencias, distribuciones y correlaciones relevantes.
La Actuación de los Docentes Frente a la Detección de los Alumnos que Presentan Trastornos Específicos del Aprendizaje (TEA), en una Escuela Primaria Rural
Authors: Montejo Ulin Inés
Published: February 2024

En el presente artículo se presenta el resultado de un estudio que se realizó sobre la actuación de los docentes, frente a la detección de los alumnos que presentan Trastornos Específicos del Aprendizaje, dicho estudio se llevó a efecto en una escuela primaria rural, de organización completa; conformado por un grupo por grado, perteneciente a la zona 15 ubicada en la ranchería Libertad Tercera Sección del municipio de Paraíso, Tabasco se recopiló la información utilizando una entrevista a docentes frente a grupo. Dicha encuesta fue aplicada al 100% de los docentes (6/6); con los objetivos de documentar los criterios que los docentes utilizan y aplican para detectar los Trastornos Específicos del Aprendizaje en los alumnos a su cargo y describir la manera o estrategia que los docentes frente a grupo aplican en sus aulas para la realizar la intervención pedagógica de manera oportuna ante la presencia de Trastornos Específicos del Aprendizaje en sus alumnos. Los principales resultados obtenidos fueron: que los docentes se percatan con gran facilidad de que el alumno, al ingresar a un grado escolar, no cuenta con los conocimientos básicos del grado cursado anteriormente, que conocen el protocolo de intervención para canalizar a los estudiantes con los especialistas que darán la atención necesaria y oportuna, pero que desconocen los Trastornos Específicos del Aprendizaje y las metodologías a emplear, mostrando poco interés para capacitarse de manera autónoma, teniendo como resultado el fracaso para alcanzar los Procesos De Aprendizaje (PDA) acorde a la fase que están cursando los alumnos.
Demostración del Espectro Hamiltoniano para un Campo de Yang-Mills no Abeliano que Poseen una Brecha de Masa Finita con Respecto al Estado de Vacío
Authors: Albuja Bustamante Manuel Ignacio
Published: February 2024

El presente artículo científico, tiene como propósito, demostrar, a través de la conjugación estructurada de distintos componentes interaccionados, que conforman el sistema de campos de Yang-Mills, (i) la conjetura de que las excitaciones más bajas de una teoría pura de Yang-Mills (es decir, sin campos de materia) tienen una brecha de masa finita con respecto al estado de vacío; (ii) la propiedad de confinamiento en presencia de partículas adicionales; y, (iii) que, dado un hamiltoniano cuántico para un campo de Yang-Mills no abeliano, existe un valor positivo mínimo de la energía. La solución de los problemas antes descritos, requiere tanto la comprensión de uno de los profundos misterios de la física sin resolver, esto es, la existencia de una brecha de masa, como la producción de un ejemplo matemáticamente completo de la teoría cuántica de campos gauge en el espacio-tiempo de cuatro dimensiones, lo que se aborda rigurosamente en el presente artículo científico.
REVIEW: REVIEW ARTICLE LIPID-BASED NANOTECHNOLOGY
Authors: Jafar Garnadi , Nazal N R. Awaludin , Sutrisno Entris
Published: February 2024

Nanotechnology is defined as engineering the creation of materials, functions, and devices on the nanometer scale. Nanoscience is increasingly developing and becoming a part of various fields, such as electronics, materials, and biology. Lipid nanoparticles are a major application in nanotechnology. In formulas II and III, smaller results were obtained compared with the other formulas. Based on the results of this study, it can be concluded that the nanostructured lipid carrier system with solid lipid poloxamer and stearic acid with liquid soybean oil lipids obtained good characteristics, and each test met the range. From the explanation above, it can be concluded that lipid-based nanotechnology has great potential in various fields such as medicine, cosmetics, and agriculture. Its use can provide great benefits such as increasing the effectiveness of drug administration, increasing the absorption of nutrients in food, and developing cosmetic products. which one is safer and more effective. To compare several types of nanoparticle methods, such as Liposomes, Neosomes, Etosomes, SLN, and NLC for selection of the lipid base, namely NLC. It is important to ensure that the use and development of this technology are safe and beneficial for humans and the environment.
Keywords : Nanotechnology, Nanoparticles, Lipid-Based Nanoparticles
Rancang Bangun Modul Praktikum Dasar-Dasar Teknik Digital
Authors: Kadir Nuralim , Asmara Bambang Panji , Wiranto Ifan
Published: February 2024

Jurusan Teknik Elektro Fakultas Teknik Universitas Negeri Gorontalo memiliki mata kuliah tentang pembelajaran teknik digital yaitu pada mata kuliah Teknik Digital dan Mikroprosesor, dimana pembelajaran teori dan praktikum dilaksanakan secara bersamaan. Pada kegiatan praktikum, media praktikum yang ada masih sangat terbatas sehingga membuat para praktikan dalam hal ini mahasiswa kesulitan untuk menerapkan berbagai teori yang telah dipelajari. Selama ini, kegiatan praktikum masih dilakukan melalui simulasi pada komputer sehingga kemampuan psikomotorik mahasiswa kurang dikembangkan. Tujuan dalam penelitian ini adalah merancang dan membangun modul praktikum dasar-dasar teknik digital yang mencakup gerbang logika dasar, flip-flop (RS, D, JK), multivibrator monostable, display seven segment, counter up down, dan aritmatic logic unit. Hasil dari penelitian modul praktikum yang dibuat diletakan dalam sebuah box koper yang terbagi menjadi 2 bagian yaitu bagian penutup (gerbang logika dasar, RS flip-flop dan D flip-flop), dan bagian utama (input toggle switch, port VCC dan GND, multivibrator monostable, JK flip-flop, display seven segment, counter up down, ALU, dan output indikator LED). Input output rangkaian terhubung dengan banana socket dan tidak terhubung satu sama lain sehingga pada proses pengujian menggunakan kabel jumper yang telah dipasang banana plug dan pengujiannya berdasarkan teori dan data sheet dari setiap modul praktikum.The Departement of Electrical Engineering, Faculty of Engineering, Universitas Negeri Gorontalo has digital engineering learning, which is Digital and Microprocessor  Engineering  courses that the theoretical and practicum  learning are conducted simultaneously. In practicum activies, the available practicum media is still limited and affect the practitioners, partycularly students, to implement the theories they have learned. In a recent period, practicum activities are still conducted through computer simulation which affects the stagnant development of psychomotor abilities. Therefore, this research aims to design and create practicum nodules for the basics of digital engineering which include basic logic gates, flip-flops (RS, D, JK), monostable multivibrators, seven segment displays, up-down counters, and unique arithmatic logic. The results of the practicum  module research that was made are placed in a suitcase box which is divided into 2 parts, the closing part (basic logic gate, RS flip-flop, and D flip-flop), and the main part (VCC and GND input toggle switch port, monostable multivibrator, JK flip-flop, seven segment display, counter up down, ALU, and output LED indicators). The input-output circuit is connected to a banana socket but it is not connected to each other so the testing process uses jumper cables that have been installed with banana plugs; the testing is based on the theory and datasheet of each practicum module.
Study of the potential for solar power plant at At Taqwa Mosque Using PV Syst
Authors: Sumarno Radiktyo Nindyo , Muntasiroh Laily , Mariani Dina
Published: February 2024

Countries located on the equator have a relatively high intensity of solar radiation. The thing that is most needed in a solar power plant is the intensity of solar radiation. Based on this, Indonesia is very suitable for implementing solar power plants. The power produced by a solar power plant is directly pro-portional to the intensity of solar radiation received by the solar panels. To maximize electrical power production, it is necessary to design a series of solar panel units to be connected in series or parallel. Solar panels connected in parallel will increase the nominal total voltage, whereas when connected in series they will increase the nominal total current. This research discusses the effect of the series-parallel configuration of solar panel installation on the power production received in a building in the campus environment. The method used to obtain the most optimal energy production is to use a combination of series and parallel solar panels. Daily sunlight data is simulated via PvSyst. The research results show that the most optimal energy production is obtained by designing a series circuit of 20 panels combined with a parallel circuit of 5 panels. The more modules connected in series, the total voltage will increase. The more modules that are connected in parallel, the total current will increase.
Sustaining collaborative learning in a rurally located university classroom in South Africa: Conducive conditions and possible threats
Authors: Adebola Oyinlola Omolara
Published: February 2024

This study investigated how collaborative learning, as a teaching and learning approach, can be enhanced to promote pre-service teachers' participation in university classrooms in rural areas of South Africa. The study aimed to identify the conducive conditions that support collaborative learning, as well as the threats that may hinder the implementation of collaborative learning in rural classrooms. Asset-based community development served as the theoretical framework for this study. A transformative paradigm was adopted, employing a participatory research design to bring together individuals with relevant experiences and opinions. The study involved fifteen participants, including five lecturers with more than five years of experience, five third-year students, and five fourth-year students from a selected university. Data was collected through focused group discussions and interviews. Thematic analysis was used to analyse the data. The findings of the study revealed that connecting activities to assessment, proper planning, linking content to students' lives, and establishing a positive classroom culture were conducive conditions for collaborative learning. On the other hand, language barriers, unconducive classroom infrastructure, and lack of infrastructure were identified as factors that could hinder the implementation of collaborative learning in this study. The study recommends the creation of favourable conditions, such as aligning activities with assessments and effective planning, to promote collaborative learning among pre-service teachers in rural university classrooms in South Africa.
Iron(II)-terpyridine DFT optimize and TDDFT
Authors: Conradie Jeanet
Published: February 2024

Density functional theory (DFT) calculated data obtained using various combinations of DFT functionals and basis sets, with and without the inclusion of Grimme D3 empirical dispersion correction.
Enhancing Electoral Integrity: A Fingerprint-Verified Voting System for Fair and Secure Elections
Authors: Gowtham R  , Mohankumar A.  , Gokul B.
Published: February 2024

Voting is a significant method through which citizens in democratic nations like India can express their opinions. Voters often use polling booths to cast their ballots. Voting is now done via an electronic voting machine thanks to advancements in technology. This essay discusses a fingerprint-verified voting machine that is Internet of Things based. The primary goals of this project are to decrease voting malpractices and make voting safer with fingerprint verification. Voter information is kept in a database along with their fingerprint. The system verifies the user's Aadhaar number and, if verified, determines whether more than one vote has been cast if the fingerprint matches the stored fingerprint. A "Matching failed" message will appear if the fingerprint matching is incorrect, and an "Aadhar not match" message will appear if the Aadhaar number is incorrect. The controller used in this project is an Arduino Uno. The user's fingerprint is used for authentication. Everybody's fingerprints differ from one another, if not slightly. A notification stating "Already voted" will appear in the event of malpractice. The ballot card is displayed and the result is stored on the cloud using the Arduino IDE for board programming. Only authorized voters may cast ballots, and the system alerts users to instances of fraud. This project ensures fair elections and protects citizens' right to vote.
SOCIAL PRODUCTION AND CONSUMPTION OF SPACE: STUDY OF PUBLIC-MARKET IN BANDUNG, INDONESIA
Authors: Ekomadyo Agus , Triwardhani Ike J.
Published: February 2024

This paper aims to examine the role of architecture in social production and consumption of space, using public markets –architectural artifacts with rich social contents– as cases. This research adopts Low’s (2017) concept of social production of space and Dovey’s (2010) social constructivism of place to uncover the social production and consumption of public markets’ space. Cihapit and Pamoyanan market in Bandung, Indonesia, are selected as research cases, due to their cultural contents, appealing to consumers from middle to upper class society. It is found several roles of architecture in social production and consumption of public market space: building typology and morphology signifies historical context of development; architectural buildings contributes to formalize trading activities and elevating social class of market traders; commodities zoning is organized based on functional and socio-historical consideration; spatial intensity is determined by access and commodities zoning; informal atmosphere emerges as a distinctive advantage of public markets; and spatial quality is relative depends on governance capacity. Although normative criteria for good design can be formulated, in practice, spatial quality of public market is relative and depends on its capacity for spatial governmentality. By exploring social production and consumption of space and place provides broader perspective on the social practices of architecture, emphasizing its contribution for social and humanity studies.
Connection between Subsurface Layers and Surface Magnetic Activity over Multiple Solar Cycles Using GONG Observations
Authors: Baird Mackenzie A. , Tripathy Sushanta C. , Jain Kiran
Published: February 2024

We investigate the spatiotemporal evolution of high-degree acoustic-mode frequencies of the Sun and surface magnetic activity over the course of multiple solar cycles, to improve our understanding of the connection between the solar interior and atmosphere. We focus on high-degree p-modes due to their ability to characterize conditions in the shear layer just below the solar surface, and analyze 22 yr of oscillation frequencies obtained from the Global Oscillation Network Group. Considering 10.7 cm radio flux measurements, the sunspot number, and the local magnetic activity index as solar-activity proxies, we find strong correlation between the mode frequencies and each activity index. We further investigate the hemispheric asymmetry associated with oscillation frequencies and magnetic activity proxies, and find that both were dominant in the southern hemisphere during the descending phase of cycle 23, while in cycle 24 these quantities fluctuated between northern and southern hemispheres. Analyzing the frequencies at different latitudes with the progression of solar cycles, we observe that the variations at midlatitudes were dominant in the southern hemisphere during the maximum-activity period of cycle 24, but the values overlap as the cycle advances toward the minimum phase. The mode frequencies at the beginning of cycle 25 are found to be dominant in the southern hemisphere following the pattern of magnetic activity. The analysis provides added evidence that the variability in oscillation frequencies is caused by both strong and weak magnetic fields.
The Width of Magnetic Ejecta Measured near 1 au: Lessons from STEREO-A Measurements in 2021–2022
Authors: Lugaz Noé , Zhuang Bin , Scolini Camilla , Al-Haddad Nada , Farrugia Charles J. , Winslow Réka M. , Regnault Florian , Möstl Christian , Davies Emma E. , Galvin Antoinette B.
Published: February 2024

Coronal mass ejections (CMEs) are large-scale eruptions with a typical radial size at 1 au of 0.21 au but their angular width in interplanetary space is still mostly unknown, especially for the magnetic ejecta (ME) part of the CME. We take advantage of STEREO-A angular separation of 20°–60° from the Sun–Earth line from 2020 October to 2022 August, and perform a two-part study to constrain the angular width of MEs in the ecliptic plane: (a) we study all CMEs that are observed remotely to propagate between the Sun–STEREO-A and the Sun–Earth lines and determine how many impact one or both spacecraft in situ, and (b) we investigate all in situ measurements at STEREO-A or at L1 of CMEs during the same time period to quantify how many are measured by the two spacecraft. A key finding is that out of 21 CMEs propagating within 30° of either spacecraft only four impacted both spacecraft and none provided clean magnetic cloud-like signatures at both spacecraft. Combining the two approaches, we conclude that the typical angular width of an ME at 1 au is ∼20°–30°, or 2–3 times less than often assumed and consistent with a 2:1 elliptical cross section of an ellipsoidal ME. We discuss the consequences of this finding for future multi-spacecraft mission designs and for the coherence of CMEs.
Solar Tachocline Confinement by the Nonaxisymmetric Modes of a Dynamo Magnetic Field
Authors: Matilsky Loren I. , Brummell Nicholas H. , Hindman Bradley W. , Toomre Juri
Published: February 2024

We recently presented the first 3D numerical simulation of the solar interior for which tachocline confinement was achieved by a dynamo-generated magnetic field. In this follow-up study, we analyze the degree of confinement as the magnetic field strength changes (controlled by varying the magnetic Prandtl number) in a coupled radiative zone (RZ) and convection zone (CZ) system. We broadly find three solution regimes, corresponding to weak, medium, and strong dynamo magnetic field strengths. In the weak-field regime, the large-scale magnetic field is mostly axisymmetric with regular, periodic polarity reversals (reminiscent of the observed solar cycle) but fails to create a confined tachocline. In the strong-field regime, the large-scale field is mostly nonaxisymmetric with irregular, quasi-periodic polarity reversals and creates a confined tachocline. In the medium-field regime, the large-scale field resembles a strong-field dynamo for extended intervals but intermittently weakens to allow temporary epochs of strong differential rotation. In all regimes, the amplitude of poloidal field strength in the RZ is very well explained by skin-depth arguments, wherein the oscillating field that gives rise to the skin depth (in the medium- and strong-field cases) is a nonaxisymmetric field structure at the base of the CZ that rotates with respect to the RZ. These simulations suggest a new picture of solar tachocline confinement by the dynamo, in which nonaxisymmetric, very long-lived (effectively permanent) field structures rotating with respect to the RZ play the primary role, instead of the regularly reversing axisymmetric field associated with the 22 yr cycle.
Ultra–short-period WD Binaries Are Not Undergoing Strong Tidal Heating
Authors: Scherbak Peter , Fuller Jim
Published: February 2024

Double white dwarf (WD) binaries are increasingly being discovered at short orbital periods where strong tidal effects and significant tidal heating signatures may occur. We assume that the tidal potential of the companion excites outgoing gravity waves within the WD primary, the dissipation of which leads to an increase in the WD’s surface temperature. We compute the excitation and dissipation of the waves in cooling WD models in evolving MESA binary simulations. Tidal heating is self-consistently computed and added to the models at every time step. As a binary inspirals to orbital periods less than ∼20 minutes, the WD’s behavior changes from cooling to heating, with temperature enhancements that can exceed 10,000 K compared with nontidally heated models. We compare a grid of tidally heated WD models to observed short-period systems with hot WD primaries. While tidal heating affects their T
eff, it is likely not the dominant luminosity. Instead, these WDs are probably intrinsically young and hot, implying that the binaries formed at short orbital periods. The binaries are consistent with undergoing common envelope evolution with a somewhat low efficiency α
CE. We delineate the parameter space where the traveling wave assumption is most valid, noting that it breaks down for WDs that cool sufficiently, where standing waves may instead be formed.
The Energy-dependent Gamma-Ray Light Curves and Spectra of the Vela Pulsar in the Dissipative Magnetospheres
Authors: Cao Gang , Yang Xiongbang
Published: February 2024

We study the pulsar energy-dependent γ-ray light curves and spectra from curvature radiation in the dissipative magnetospheres. The dissipative magnetospheres with the combined force-free (FFE) and Aristotelian are computed by a pseudo-spectral method with a high-resolution simulation in the rotating coordinate system, which produces a near-FFE field structure with the dissipative region only near the equatorial current sheet outside the light cylinder. We use the test-particle trajectory method to compute the energy-dependent γ-ray light curves and phase-average and phase-resolved spectra by including both the accelerating electric field and radiation reaction. The predicted energy-dependent γ-ray light curves and spectra are then compared with those of the Vela pulsar observed by Fermi. Our results can generally reproduce the observed trends of the energy-dependent γ-ray light curves and spectra for the Vela pulsar.
Reconnection along a Separator in Shock Turbulence
Authors: Ng J. , Bessho N. , Dahlin J. T. , Chen L.-J.
Published: February 2024

Numerous structures conducive to magnetic reconnection are frequently observed in the turbulent regions at quasi-parallel shocks. In this work, we use a particle-in-cell simulation to study 3D magnetic reconnection in shock turbulence. We identify and characterize magnetic null points, and focus on reconnection along the separator between them. We identify a reconnection region with strong parallel current, a finite parallel potential, and counterrotating electron flows. Electrons are shown to be accelerated by the parallel electric field before being scattered at the null.
Hunting for Hydrated Minerals on Trans-Neptunian Objects
Authors: Seccull Tom , Fraser Wesley C. , Kiersz Dominik A. , Puzia Thomas H.
Published: February 2024

We present new optical reflectance spectra of three potentially silicate-rich trans-Neptunian objects (TNOs). These spectra were obtained with the aim of confirming past hints and detections of λ ∼ 0.7 μm absorption features associated with the presence of iron-bearing phyllosilicates. Our new spectrum of 120216 (2004 EW95) presents clearly detected absorption features that are similar in shape to hydrated mineral absorption bands present in the spectra of aqueously altered outer main belt asteroids. Four new reflectance spectra of 208996 (2003 AZ84) obtained at separate epochs all appear featureless, but they vary significantly in spectral gradient (between ∼3.5%/0.1 μm and ∼8.5%/0.1 μm) on a timescale consistent with this object’s nominal rotational period. We report the first four optical reflectance spectra of 90568 (2004 GV9), finding them all to be featureless but consistent with colors previously reported for this object. We speculate that impacts are the only mechanism capable of delivering, excavating, or forming hydrated minerals at the surfaces of TNOs in detectable concentrations; as a result, any deposits of hydrated minerals on TNOs are predicted to be localized and associated with impact sites. Globally altered TNOs (as observationally suggested for 2004 EW95) plausibly formed more easily at smaller heliocentric distances (r

H
< 15 au) before being transplanted into the current trans-Neptunian population.