bluuebunny/crossref_metadata_2025 huggingface dataset:
Conductas conflictivas y convivencia escolar: análisis desde el modelo ecológico
Authors: Ochoa Cervantes Azucena de la Concepción , Garbus Pamela , Osornio Andrea Morales
Published: September 2021

El objetivo de este trabajo es analizar la prevalencia de percepción de tres conductas conflictivas: desinterés, desmotivación y deshonestidad académica en estudiantes de secundarias públicas de un municipio del semidesierto queretano de México. El estudio en el que se basa es de corte epidemiológico observacional, analítico transversal, y el muestreo es probabilístico y estratificado según el tipo de escuela y nivel de marginación de las secundarias. La convivencia escolar se aborda desde una perspectiva ecológica que establece dos dimensiones para su estudio: la personal, que incluye la edad y el sexo, y la institucional, integrada por tres subsistemas: macrosocial, mesosocial y microsocial. Se encontró una dependencia entre la percepción de conductas conflictivas y el nivel de marginación de la escuela: las escuelas con niveles menores de marginación reportaron mayor prevalencia de percepción de conductas conflictivas, y también se observó una mayor prevalencia en las escuelas generales en comparación con las telesecundarias. El estudio plantea líneas de indagación sobre las condiciones macrosociales de la institución y su vínculo con la convivencia escolar.
Current Aspects of Genetic Diagnosis of 21-Hydroxylase Insufficiency
Authors:   Scientific and Research Institute of Obstetrics, Gynaecology and Reproductive Medicine named after D.O. Ott, St. Petersburg, Russian Federation, Osinovskaya N.S. ,   I.I. Mechnikov Northwestern State Medical University, Russian Ministry of Health, Russian Federation, Nasykhova Yu.A. ,   Scientific and Research Institute of Obstetrics, Gynaecology and Reproductive Medicine named after D.O. Ott, St. Petersburg, Russian Federation, Yarmolinskaya M.I. ,   Scientific and Research Institute of Obstetrics, Gynaecology and Reproductive Medicine named after D.O. Ott, St. Petersburg, Russian Federation,   I.I. Mechnikov Northwestern State Medical University, Russian Ministry of Health, Russian Federation, Glavnova O.B. ,   Scientific and Research Institute of Obstetrics, Gynaecology and Reproductive Medicine named after D.O. Ott, St. Petersburg, Russian Federation, Glotov A.S. ,   Scientific and Research Institute of Obstetrics, Gynaecology and Reproductive Medicine named after D.O. Ott, St. Petersburg, Russian Federation
Published: September 2021

Objective of the Review: To discuss the current peculiarities of 21-hydroxylase insufficiency diagnostics. Key Points. Congenital adrenal hyperplasia (CAH) is a group of autosomal-recessive pathologies, associated with a defective enzyme or transport protein participating in cortisol biosynthesis. Currently, there is information on CAH genetics including information on 21-hydroxylase insufficiency. Neonatal screening, antenatal and postnatal methods to diagnose 21-hydroxylase deficit have been developed. Timely diagnosis and correct therapy have been found to facilitate normal physical and mental development of patients. Molecular genetic testing for CAH associated with 21-hydroxylase deficit is widely used both in Russia and globally and is of importance for differential diagnosis, identification of pathogenic CYP21A2 gene carriers and adequate genetic counselling. The best strategy to diagnose 21-hydroxylase insufficiency is 2-stage CYP21A2 gene analysis. The test should include both gene sequence analysis and identification of point replacements, minor deletions and duplication (e.g., dideoxynucleotide chain-termination method or Next Generation Sequencing), and identification of extended deletions and duplication (multiplex ligation dependent probe amplification, real-time polymerase chain reaction). Such a comprehensive approach can help finding a majority of types of possible changes. Conclusion. Correct genetic testing methods ensure detection of pathogen variants in CYP21A2 gene; evaluation of the possible rate of clinical manifestations of the disease, both during antenatal testing and if an unknown clinical CAH form is encountered; prescribing an adequate therapy; and ensuring genetic counselling in order to develop a management strategy, including when planning for pregnancy in a woman with confirmed CAH. Keywords: congenital adrenal hyperplasia, CYP21A2 gene, genetic counselling, 21-hydroxylase
New Possibilities of Personalised Menopausal Phytotherapy with Resveratrol
Authors:   Tyumen State Medical University of the Ministry of Health of the Russian Federation, Tyumen, Russian Federation, Vinokurova E.A. , Ismailova D.Kh. ,   Lomonosov Moscow State University, Moscow, Russian Federation, Khvoschina T.N. ,   Tyumen State Medical University of the Ministry of Health of the Russian Federation, Tyumen, Russian Federation
Published: September 2021

Objective of the Review: To study the efficiency of a novel phytoestrogen Resveratrol in menopausal syndrome. Key Points. The article discusses Russian and foreign studies confirming that trans-Resveratrol has potent estrogen-like effect and a wider potency as compared to other phytoestrogens, since it affects both α- and β-estrogen receptors. The clinical properties of Resveratrol have been analysed: impact on menopausal symptoms and joint and muscle pain, antioxidant, anti-inflammatory, immunomodulating, anti-neurodegenerative, and cartilage protection action. Conclusion. Management of menopausal disorders can be both combined and individual, taking into account the needs of a patient. Resveratrol boosts the opportunities of personified menopausal phytotherapy. Keywords: menopause, phytotherapy, Resveratrol, trans-resveratrol, antioxidant, anti-ageing therapy, phytoestrogens, hot flushes
Pediatricians Should Know About Kratom: A Pediatrician’s Perspective
Authors: Eldridge Whitney
Published: September 2021

Kratom is an herbal alkaloid dietary supplement that acts agonistically at opioid receptors. It is increasingly used by those with opioid dependency to treat symptoms of opioid withdrawal. Classification and regulation of kratom is controversial. Currently it is unregulated, widely available and heavily advertised. Advocates tout its potential to help those with opioid dependency however risks to kratom use are well documented. It has been associated with dependency, withdrawal, toxicity and more recently neonatal abstinence syndrome (NAS) or withdrawal in newborns. For these reasons, pediatricians need to be aware of its existence and potential to impact their patients.
Time to Hit Opioids Early and Hard
Authors: Moss Ronald
Published: September 2021

A turning point in the HIV epidemic was the introduction of protease inhibitors. It was clear to some that treatment of HIV infected individuals with these potent antiviral agents was needed as early as possible, and with this paradigm shift, HIV became a livable chronic disease (1). There are some lessons learned from the HIV epidemic relevant to the current synthetic opioid epidemic.
Multidisciplinary Management of Primary Sacral Tumors: A Tertiary Care Center’s Experience and Literature Review
Authors: Chander Venugopal Sarath , Govindasamy Ramachandran , Tukkapuram Venkata Ramakrishna , Gopal Swaroop , Rudrappa Satish
Published: September 2021

Sacral tumors are rare and can be benign or malignant. Their management is multifactorial and is based on the pathology, extent, and local and distant spread. Managing sacral tumors is challenging due to their proximity to visceral and neural structures. Surgical wide excision has been the standard of care for aggressive benign and malignant tumors. Our purpose was to evaluate the outcomes of a multimodal approach to managing primary sacral tumors in Sakra World Hospital, a tertiary spine care center in Bengaluru, India and perform a literature review to determine a workflow pathway. Our study was a retrospective review of patient records and included 15 patients with primary sacral tumors. Eleven surgically treated patients were evaluated clinically and radiologically and underwent biopsy before surgical excision by an all-posterior approach. A multidisciplinary approach that included intraoperative neural monitoring, plastic reconstruction, adjuvant chemotherapy, and radiotherapy was implemented whenever necessary. Sacral root preservation was attempted whenever feasible. Functional outcomes (based on the Visual Analog Scale [VAS] and Biagini scoring system) were analyzed along with disease control, with a minimum of 2 years of follow-up. The mean follow-up was 29±9.8 months. The mean VAS score significantly improved from 7.8±2.6 to 3.7±3.8 (p =0.026). Bowel function showed statistically significant improvement, from a mean score of 0.81±0.47 to 0.63±0.52 (p =0.026) at 2 years of follow-up. The mean pretreatment motor and bladder function scores were 0.53±0.31 and 0.74±0.44, respectively, improving to 0.48±0.33 and 0.68±0.56 at follow-up but without statistical significance. There was no significant loss of function, which is expected in radical sacral resections. In conclusion, primary sacral tumors require a multidisciplinary approach and management for optimal outcomes. A stand-alone posterior approach can be employed to treat most sacral lesions. En-bloc wide resection is the optimal treatment for primary malignant and aggressive benign tumors. Preservation of at least one functional S2 nerve root is imperative to preserve bowel and bladder function.
Global Sagittal Alignment and Clinical Outcomes after 1–3 Short-Segment Lumbar Fusion in Degenerative Spinal Diseases
Authors: Youn Yung-Hun , Cho Kyu-Jung , Na Yeop , Kim Jeong-Seok
Published: September 2021

Study Design: Level III retrospective study.Purpose: We investigated the impact of short-segment lumbar fusion on the restoration of global sagittal alignment and the correlations between spino-pelvic parameters and clinical outcomes.Overview of Literature: Sagittal imbalance leads to energy consumption and pain in maintaining a standing position. For adult spinal deformity, it is critical to create optimal lumbar lordosis (LL) in order to achieve restoration of sagittal imbalance. However, surgeons do not pay attention to correcting LL in short-segment lumbar fusion.Methods: A total of 69 patients with transforaminal lumbar interbody fusion (TLIF) for degenerative spinal disease were evaluated with a minimum 2-year follow-up. All patients underwent TLIF with hyper-lordotic angle cages to achieve higher LL. Radiological spino-pelvic parameters including sagittal vertical axis (SVA) and clinical outcomes using the Oswestry Disability Index (ODI) and Numeric Rating Scale (NRS) were evaluated.Results: The average LL was 35.8°±9.9° before surgery, 42.3°±9.3° 1 year after surgery, and 40.3°±10.2° 2 years after surgery (p <0.01). The average SVA was 43.1±6.2 mm before surgery, 21.2±4.9 mm 1 year after surgery, and 34.0±4.7 mm 2 years after surgery (p <0.01). The average LL and SVA improved in two- or three-segment fusion, but not in one-segment fusion. The correlation between ΔLL and ΔSVA was significant in all segment fusions. The correlation between ΔLL and ΔSVA was more significant at the L4–5 and L5–S1 segments than at L3–4. ODI was significantly correlated with SVA (p <0.05). NRS showed no correlation with the radiological parameters.Conclusions: Two- or three-segment lumbar fusion using hyper-lordotic angle cages improved LL and SVA. A significant correlation between the correction of LL and SVA was found. Higher correction of LL using hyper-lordotic angle cages is thus recommended in short-segment lumbar fusion, since postoperative improvements of SVA significantly affect clinical outcomes.
Impact of Knowledge-based Program Management Resource on Social Enterprise Sustainability: A Structural Equation Modelling Approach
Authors: Arif-Ud-Din  , Shah Syed Mohsin Ali , Jahangir Muhammad
Published: September 2021

The focus of this research is to look at knowledge-based programme management resources as a starting point for investigating the relationship between Team programme management resources and social enterprise sustainability in underdeveloped countries. This article examines data from 300 programme management personnel of social businesses in Pakistan who responded to a self-administered and online survey. The link between team programme management resources and social business sustainability was investigated using structural equation modelling (CB-SEM). A total of 9 critical indicators of the team programme management assets have a substantial impact on the three sustainability pillars (Social, economic and environmental). This research contributes to the understanding of the relationship between programme management resources and the long-term sustainability of social enterprises. Few publications have looked into intangible programme management resources as a basis of sustainability using the RBV of the organization. This study adds to the body of knowledge on the RBV of the business and advances our consideration of programme management resources as a foundation of long-term sustainability.
Hepatitis C Virus Infection in Pregnancy and Children: Its Implications and Treatment Considerations with Directly Acting Antivirals: A Review
Authors: Rana Ramesh , Dangal Rajkumar , Singh Yogendra , Gurung Ram Bahadur , Rai Bhim , Sharma Amit Kumar
Published: September 2021

Hepatitis C virus infection (HCV) is a global health problem affecting >71 million people worldwide with chronic hepatitis C, 40% reproductive age group, and 8% pregnant women. Intravenous drug abuse, multi-transfusions are major risk factors in adults, while vertical transmission in pediatric population. It commonly presents as a chronic liver disease, has higher risk of liver cirrhosis and even progression to hepatocellular carcinoma. Therefore, proper screening of high-risk populations including pregnancy is recommended. All diagnosed chronic hepatitis C cases should be treated with directly acting anti-virals (DAAs) including pre-conception which has a cure rate of >95%. This would reduce the disease burden, vertical transmission, and disability associated. However, no DAAs regimens recommendation till date due to lack of evidence on adverse fetal outcomes and are concerned about the pharmacokinetic effect regarding physiological changes during pregnancy. Therefore, in this review, we have tried to explore the possible use of DAAs regimens and their safety issues during pregnancy, and possible consideration of few pan-genotypic regimens in the late 2nd and early 3rd trimester. This would not only prevent vertical transmission and decrease disease burden but also help to meet the WHO 2030 target of HCV elimination as a major public health problem.
ASSESSMENT OF WATER BODIES QUALITY OF THE VOLGA-AKHTUBA FLOODPLAIN FROM ECOLOGICAL VIEWPOINT
Authors:   Volgograd State Agrarian University, Semenenko S. Ya. , Morozova N. V. ,   Federal Research Center “Nemchinovka”,, Marchenko S. S. ,   Volgograd State Agrarian University, Kolobanova N. A. ,   Volgograd State Agrarian University
Published: September 2021

Purpose: to assess the quality of water in water bodies of the Volga-Akhtuba floodplain from an ecological viewpoint, taking into account the modern regulatory framework in the field of environmental protection. Materials and Methods. To assess the quality of natural waters from an ecological viewpoint, a complex indicator calculated by basic analyte markers that characterize typical negative impacts was used. The following hydrochemical indicators were taken as analyte markers: pH, mineralization (dry residue), suspended solids of natural origin, total iron, total manganese, ammonium (N), nitrites (N), nitrates (N), phosphates (PO4), chemical oxygen demand (COD). Results. The ecological state of water bodies was determined by hydro-chemical indicators of surface waters and bottom sediments using the example of such representative objects as water bodies on the territory of the Volga-Akhtuba floodplain: lakes Peschanoe, Varyuzhka, Zhestkovo, erik Chayka, lakes Beshenoe, Chubatoe, Yamy, erik Shumrovatyy, lake Shirokogorloe. In accordance with the provisions of GOST R 58556-2019 “Assessment of water quality in water bodies from an ecological point of view”, the quality of water from an ecological viewpoint, the degree of quality disturbance and changes in the state of aquatic ecosystems under anthropogenic load have been determined. Conclusions. Petroleum products have been recorded in the water bodies of the Volga-Akhtuba floodplain (lake Varyuzhka, erik Shumrovatyy). The analysis of hydrochemical indicators of water quality and bottom sediments shows that currently the overall level of pollution of the considered water bodies does not reach critical levels of permissible values.
ENSURING WATER INTAKES ECOLOGICAL SAFETY OF AGRICULTURAL WATER SUPPLY SYSTEMS
Authors:   South-Russian State Polytechnic University (NPI) named after M. I. Platov, Khetsuriani E. D. , Kurdagia F. Sh. ,   South-Russian State Polytechnic University (NPI) named after M. I. Platov, Khetsuriani Te. E. ,   South-Russian State Polytechnic University (NPI) named after M. I. Platov, Novocherkassk, Khetsuriani T. E. ,   Don State Technical University
Published: September 2021

Purpose: substantiation of the relevance of ensuring environmental safety of water purification facilities in agricultural water supply systems by creating a complex of specialized protective equipment. Materials and Methods. The methodological approaches of this work in studying and improving water projects are based on the work of domestic and foreign scientists. Results and Discussion. An analysis of the agricultural water supply systems operation in Rostov, Volgograd, Astrakhan regions, Stavropol, Krasnodar and Altai regions and the Yamalo-Nenets Autonomous District was carried out, as a result, the lack of environmental safety of water intakes of water supply systems was revealed. To solve this problem, a scientific substantiation of the environmentally sustainable operation of a specialized type of natural-technical system “natural water environment – water industry complex – agricultural water supply system” was carried out. Conclusions. The proposed systematic approach to solving vital problems of ensuring the environmental safety of water intakes of water industry systems will ensure uninterrupted supply of the required estimated high-quality water supply to consumers under any operating modes of agricultural water supply systems (slush, suspension, plankton, dreisen, etc.). At the same time, the complex of water purification facilities will improve the river ecosystem.
The international use of the chinese renminbi
Authors: Kondratov Dmitriy
Published: September 2021

The paper examines the prospects of the Chinese renminbi, its impact on the economy of the PRC and the role of the international currency market, these issues being the subject of both professional and the broader public interest. The author focuses on the process of the renminbi development into a global currency that could be, and in some ways already is, an alternative to other reserve assets.
Global external debt during COVID-19 pandemic
Authors: Balyuk Igor
Published: September 2021

The article contains an analysis of the dynamics and structure of the external debt of various countries and groups of countries in the context of the coronavirus pandemic. The authors conclude that at the beginning of 2021, the ratio of external debt to GDP almost reached the level that was noted on the eve of the global financial and economic crisis of 2008-2009. A trigger for a new global crisis may be the exacerbation of problems in one or more segments of the economy of the European Union, Great Britain, the United States, or a number of large developing countries.
ANTI-NAPOLEONIC CAMPAIGNS OF 1805–1807 AND THE MILITARY THEME IN RUSSIAN POETRY
Authors:   Institute of Russian Literature (Pushkinskij Dom), Russian Academy of Sciences, Khaliullin Karim Rishatovich
Published: September 2021

The article analyzes the connections between the offi cial rhetoric and the poetry on Napoleonic War of 1805–1807 in the Russian Empire. During the fi rst period of the war (War of the Third Coalition), only a handful of poems was published, whereas the second period (War of the Fourth Coalition) produced a much bigger volume of verse. The author suggests that the quantitative difference in the poetical output between these two phases of the War is directly related to the strategy of the offi cial rhetoric, since in the beginning of the War of the Third Coalition Emperor Alexander I did not publish a special manifesto (just the Recruitment Ordinance) while after the beginning of the War of the Fourth Coalition three Emperor’s manifestos were released. These documents shaped an ideological coordinate system in which the poets were able to produce new texts.
D. V. VENEVITINOV’S SONNET «TO THEE, OH PURE SPIRIT, THE SOURCE OF INSPIRATION…»: DATING, POETICS, SCHELLINGIAN PLOT
Authors:   Institute of Russian Literature (Pushkinskij Dom), Russian Academy of Sciences, Zolotukhin Veniamin Timofeevich , Grigor’eva Elena Nikolaevna ,   St. Petersburg State University
Published: September 2021

The context of D. V. Venevitinov’s philosophical writings reveals an underlying Schellingian content within the sonnet «To Thee, Oh Pure Spirit, the Source of Inspiration…». The particularities of the text’s poetics testify to the role it plays in the emergence of Venevitinov’s lyrical persona. The study of ideological genesis and artistic structure of the poem allows to date it more precisely.
SOME THOUGHTS ON THE NOSE BY N. V. GOGOL
Authors:   St. Petersburg State University, Kleiner Yuri Aleksandrovich
Published: September 2021

The three versions of The Nose by Nikolai Gogol refl ect the evolution of the author’s concept and its realization, from a «dream» to an unmotivated incident. The preservation of the elements of the dream from the original version in the 1836 and 1842 publications suggests the presence of the motif in the storylines of both characters, but in an encrypted form. For encoding, the 12 days’ difference between the Julian and Gregorian calendars (March 25 — April 7 in the 1842 edition) was used, which accommodated the events of one night in the original version.
BETWEEN V. YA. BRYUSOV AND E. V. ANICHKOV
Authors:   Lomonosov Moscow State University, Bogomolov Nikolai Alekseevich
Published: September 2021

The article introduces the letters of V. Ya. Bryusov and E. V. Anichkov of 1906-1913. Plans to publish the collected works by A. S. Pushkin, a project initiated by the Deyatel Russian Book Association, stand out amid the various projects that the correspondents discuss.
LOLITA IN LOLITA
Authors:   independent researcher, Levina-Parker Masha
Published: September 2021

The article explores the construction of the image of Lolita in the novel. Seemingly, the image of Lolita is a complete construct of Humbert’s narration. However, Nabokov’s way of composing the no vel allows certain empirics contributing to formation of Lolita’s image to escape the control of the narrator. In order to understand how Lolita’s image is constructed, it is necessary to analyze how Nabokov constructs Humbert’s narration about Lolita. Humbert’s narration contains certain hidden autonomous signs that diverge from visible dimension of his narration and modify the portrait of Lolita.
M. A. BULGAKOV IN SEARCH OF A REVOLUTIONARY PLAY: A STAGE CHRONICLE OF THE DAYS OF THE TURBINS
Authors:   Institute of Russian Literature (Pushkinskij Dom) Russian Academy of Sciences, Khachaturian Liubov’ Valerievna ,   National Research University Higher School of Economics (Moscow)
Published: September 2021

The article explores the genre specifi city of Mikhail Bulgakov’s theatrical albums from the collection of the Institute of Russian Literature. Using the materials of Bulgakov’s fi rst theatrical album (1925–1927), the stage history of the play The Days of the Turbins and the further development of the plot of the Theatrical Novel (Notes of the Deceased) are clarifi ed. The materials of the albums are compared with Bulgakov diary entries of 1923–1924 (My Diary / Under the Heel).
AT THE GATES OF THE RUSSIAN HANDWRITTEN TRADITION OF MODERN TIMES
Authors:   Lomonosov Moscow State University, Alpatov Sergey Viktorovich
Published: September 2021

[Review]: Shamin S. M. Inostrannye «pamfl ety» i «kur’ezy» v Rossii XVI — nachala XVIII stole tiia. M.: Ves’ Mir, 2020. 392 s.
RUSSIAN TRAVEL WRITING IN RECENT STUDIES
Authors:   Institute of Russian Literature (Pushkinskij Dom), Russian Academy of Sciences, Solovev Andrei Iurievich ,   University of Tartu
Published: September 2021

The overview article examines the modern philological study of Russian travel writing before the modernist era through the prism of the «travel literature» / «literary travel» opposition. A special emphasis is laid on the problem of bibliography of the material, the advantages and disadvantages of existing approaches are considered.
The Effect of Consanguinity on Reproductive Fitness and Selection Intensity in the Muslim Population of Western Uttar Pradesh, India
Authors: Afzal Mohammad
Published: September 2021

ABSTRACT The study sought to ascertain the adverse effects of consanguinity among Muslim parents of Aligarh city located in western Uttar Pradesh in India. More than 478 families were visited and data were collected from only 100 of them being inbred to varying degrees of consanguinity. It was found that increasing degree of consanguinity decreases fertility (R2 = 0.2671, r = -0.1568), but increases mortality (R2 = 0.3161, r = 0.5622). Selection intensity (R2 = 0.1734, r = 0.4164) and secondary sex ratio (R2 = 0.3757, r = 0.6129) also go up as the degree of consanguinity increases. However, the genomic basis of Runs of Homozygosity (ROH) is a more accurate method of calculating homozygosity. Next Generation Sequencing may help better understand ROH and their utility as a tool for inbreeding detection. To avoid the inbreeding load, there is a need to raise public awareness of reproductive health and the potential negative effects of consanguinity.
Some hypergeometric summations formulas and series identities with applications
Authors:   University, Jaipur, India, Gupta R. , Menon M. ,   University, Jaipur, India, Mittal E. ,   University, Jaipur, India
Published: September 2021

In the paper we present two incomplete Gaussian hypergeometric formulas in summation form by specific known formulas.We also developed each of these formulas and how they use to derive double series identities in general forms.
Transformation formulas of incomplete hypergeometric functions via fractional calculus operators
Authors:   Rajasthan Technical University, Kota, India, Jangid Kamlesh , Purohit Sunil Dutt ,   Rajasthan Technical University, Kota, India, Suthar Daya Lal ,   Wollo University, Dessie, Ethiopia
Published: September 2021

The desire for present article is to derive from the application of fractional calculus operators a transformation that expresses a potentially useful incomplete hypergeometric function in various forms of a countable sum of lesser-order functions. Often listed are numerous (known or new) specific cases and implications of the findings described herein
N(k)-paracontact three metric as a Eta-Ricci soliton
Authors:   University of Calcutta, West Bengal, India, Kar Debabrata , Majhi Pradip ,   University of Calcutta, West Bengal, India
Published: September 2021

In this paper, we study Eta-Ricci soliton (η-Ricci soliton) on three dimensional N(k)-paracontact metric manifolds. We prove that the scalar curvature of an N(k)-paracontact metric manifold admitting η-Ricci solitons is constant and the manifold is of constant curvature k. Also, we prove that such manifolds are Einstein. Moreover, we show the condition of that the η-Ricci soliton to be expanding, steady or shrinking. In such a case we prove that the potential vector field is Killing vector field. Also, we show that the potential vector field is an infinitesimal automorphism or it leaves the structure tensor in the direction perpendicular to the Reeb vector field ξ. Finally, we illustrate an example of a three dimensional N(k)-paracontact metric manifold admitting an η-Ricci soliton
Coefficient estimates for certain subclasses of starlike functions of complex order associated with hyperbolic domain
Authors:   National University of Science and Technology, Muscat, Sultanate of Oman, Karthikeyan K.R. , Murugusundaramoorthy G. ,   University, Vellore, Tamilnadu,India, Nistor-Serban A. ,   Transilvania University of Brasov, Romania
Published: September 2021

In this paper, we obtain the coefficient inequalities for functions in certain subclasses of Janowski starlike functions of complex order which are related starlike functions associated with a hyperbolic domain. Our results extend the study of various subclasses of analytic functions. Several applications of our results are also mentioned
Generalized Bernstein type operators
Authors:   Transilvania University of Brasov, Romania, Melesteu Alexandra Diana
Published: September 2021

In this paper we investigate certain properties of a class of generalized Bernstein type operators
On univalence of an integral operator
Authors:   Transilvania University of Brasov, Romania, Pescar Virgil , Sasu Adela ,   Transilvania University of Brasov, Romania
Published: September 2021

In this paper we define an integral operator for analytic functions in the open unit disk and we determine certain univalence criteria for this integral operator
On forward iterated Hausdorffness and development of embryo from zygote in bitopological dynamical systems
Authors:   Gauhati University, Assam, India, Acharjee Santanu , Goswami Kabindra ,   Gauhati University, Assam, India, Sarmah Hemanta Kumar ,   Gauhati University, Assam, India
Published: September 2021

Topological dynamical system is an area of dynamical system to investigate dynamical properties in terms of a topological space. Nada and Zohny [Nada, S.I. and Zohny, H., An application of relative topology in biology, Chaos, Solitons and Fractals. 42 (2009), 202-204] applied topological dynamical system to explore the development process of an embryo from the zygote until birth and made three conjectures. In this paper, we disprove conjecture 3 of Nada and Zohny [Nada, S.I. and Zohny, H., An application of relative topology in biology, Chaos, Solitons and Fractals. 42 (2009), 202-204] by applying some of our mathematical results of bitopological dynamical system. Also, we introduce forward iterated Hausdorff space, backward iterated Hausdorff space, pairwise iterated Hausdor_ space and establish relations between them in bitopological dynamical system. We formulate the function that represents cell division (specially, mitosis) and using this function we show that in the development process of a human baby from the zygote until its birth, there is a stage where the developing stage is forward iterated Hausdorff
Meromorphic solutions of higher order non-homogeneous linear difference equations
Authors:   University of Mostaganem, Mostaganem, Algeria, Belaıdi Benharrat , Bellaama Rachid ,   University of Mostaganem, Mostaganem, Algeria
Published: September 2021

In this paper, we investigate the growth of meromorphic solutions of nonhomogeneous linear difference equation A_n(z)f(z + c_n) + · · · + A_1(z)f(z + c_1) + A_0(z)f(z) = A_{n+1}(z), where A_{n+1 (z), · · · , A0 (z) are (entire) or meromorphic functions and c_j (1, · · · , n) are non-zero distinct complex numbers. Under some conditions on the (lower) order and the (lower) type of the coefficients, we obtain estimates on the lower bound of the order of meromorphic solutions of the above equation. We extend early results due to Luo and Zheng.
Drazin inverse: representation, approximation, continuity and illustrations
Authors:   University Tahar Moulay of Saida, Saida, Algeria, Bendjedid Sadli , Messirdi Bekkai ,   High School of Electrical and Energetic Engineering-Oran, Algeria, Messirdi Sofiane ,   University of Oran1, Ahmed Ben Bella, Algeria
Published: September 2021

In this paper, we present some characteristics and expressions of the Drazin inverse for matrices and bounded linear operators in Banach spaces. We give a survey of some of results on the continuity of the Moore-Penrose and Drazin inverse, direct technics for computing the Drazin inverse are discussed, they are based on Euler-Knopp Method and characterized in terms of a limiting process. The examples presented are for illustrative purposes, some of which are provided for testing the considered iterative processes
A novel epidemic model to analyze and control the chaotic behavior of COVID-19 outbreak.
Authors:   Maharshi Dayanand University, Haryana, India, Chugh Renu , Kumar Amit ,   Maharshi Dayanand University, Haryana, India, Kumari Sudesh ,   Government College for Girls Sector14, Haryana, India
Published: September 2021

The coronavirus disease 2019 (COVID-19) has been spread all over the world. There are more than 43.14 million COVID-19 confirmed cases and over 1.15 million deaths reported worldwide till October 26, 2020. As the proper treatment/vaccine is not available, most of the countries are relying on various preventive measures to check the spread of epidemic. The aim of this article is to analyze the impact of corona preventive measures on the spread of COVID-19 by employing a novel epidemic model. Moreover, time series and bifurcation analysis techniques have been used to estimate this impact. To prove the validity of our model, we apply our model on highly affected countries such as China, Italy, USA, UK and India. Our findings might be very useful tool for decision holders and policy makers to take the right decisions in a timely way to control the outbreak of COVID-19, knowing the uncertainties about the coronovirus disease. We show a good agreement between the reported data and the estimations given by our model.
Раціональна антигіпертензивна терапія пацієнтів старших вікових груп
Authors: Kovalyova O. M.
Published: September 2021

The article is devoted to the consideration of hypertensive older patients management with accent on pharmacological treatment. For justification of the choice of antihypertensive drugs on the principles of the evidence-based medicine the results of a randomized controlled clinical trials with inclusion of the old and older hypertensive patients are shown. Асcording to published systematic reviews and meta-analysis in comparative aspects are given the effects of different antihypertensive drugs related to their influence on cardiovascular events in this category of patients. Recommendations of rational pharmacotherapy of hypertension relevant to age-specific features of patients are taken with variant positions according to suggestions of leading experts and international organizations – the European Society of Cardiology; the European Society of Hypertension; American Society of Hypertension; the European Society of Hypertension-European Union Geriatric Medicine Society Working Group on the Management of Hypertension in Very Old, Frail Subjects; Canadian Hypertension Education Program; the American College of Physicians and the American Academy of Family Physicians; National Institute for Health and Clinical Excellence. The tactic of treatment of geriatric patients with hypertension is summarized.
EFFECTIVENESS IN HUMANS OF
Authors: Angulo Orlando , Restrepo Hector Fabio , León Higuera José Gabriel , Leon Garcia Mario , Mendive Fernando , Politi Matteo
Published: September 2021

Background: 

Since the SARS-CoV-2 pandemic emerged in December 2019, it has triggered 4.4 million deaths and strained health systems across the world. Yet more than a year and a half since the pandemic emerged, therapeutic drugs to treat COVID-19 disease are limited.

Objective

To investigate the therapeutic potential of a nicotinic Cholinergic Agonists Mixture (CAM), delivered daily as oral drops and as nasal spray, in alleviating ten common COVID-19 related symptoms in 80 symptomatic human adults with confirmed SARS-CoV-2. 

Methods

This randomized open-label pilot trial recruited 80 symptomatic adults with confirmed SARS-CoV-2 infection after RT-PCR+ test less than five days. Participants were recruited from databases of several Colombian hospitals and were randomly assigned to the control group, which received the Standard of Care (SOC) treatment (outpatient treatment), or the intervention group, which received SOC combined with the Cholinergic Agent Mixture (CAM + SOC). Both groups received their treatment for a total of 14 days. The duration of symptoms was compared across the 14-day period.

Results:

This study found statistically significant reductions in symptom duration for 5 out of 10 symptoms, including dyspnea (reduction of 4.43 days [95% CI: 2.70 ; 6.15], p <0.0001), cough (reduction of 3.18 days [95% CI: 1.29 ; 5.06],  p=0.0089), cephalea (reduction of 3.13 days [95% CI: 1.53 ; 4.72], p= 0.0019), muscle fatigue (reduction of 4.18 days [95% CI: 2.03 ; 6.32], p=0.0019) and general malaise (reduction of 5.98 days [95% CI: 4.20 ; 7.76],  p <0.0001).The study found no significant reductions in the duration of the following symptoms: fever, ageusia, anosmia, chest tightness, and nasal congestion.

Conclusion: 

In comparison to the control group, the intervention group witnessed statistically significant and clinically relevant reductions in the duration of 5 out of 10 common COVID-19 disease symptoms within two weeks. 

This includes a reduction of approximately 4.4 days in the duration of dyspnea, a symptom that appears to be strongly correlated to severe COVID-19 disease and admission to Intensive Care Units.

Further studies are needed to confirm these preliminary findings and to evaluate whether this specific nicotinic cholinergic agonists mixture could have implications for public health.
CHOLINERGIC AGONISTS AGAINST COVID-19 IN HUMANS. RESULTS FROM A RANDOMIZED OPEN LABEL PILOT TRIAL
Authors: Angulo Orlando , Restrepo Hector Fabio , León Higuera José Gabriel , Leon Garcia Mario , Mendive Fernando , Politi Matteo
Published: September 2021

Background: 

Since the SARS-CoV-2 pandemic emerged in December 2019, it has triggered 4.4 million deaths and strained health systems across the world. Yet more than a year and a half since the pandemic emerged, therapeutic drugs to treat COVID-19 disease are limited.

Objective

To investigate the therapeutic potential of a nicotinic Cholinergic Agonists Mixture (CAM), delivered daily as oral drops and as nasal spray, in alleviating ten common COVID-19 related symptoms in 80 symptomatic human adults with confirmed SARS-CoV-2. 

Methods

This randomized open-label pilot trial recruited 80 symptomatic adults with confirmed SARS-CoV-2 infection after RT-PCR+ test less than five days. Participants were recruited from databases of several Colombian hospitals and were randomly assigned to the control group, which received the Standard of Care (SOC) treatment (outpatient treatment), or the intervention group, which received SOC combined with the Cholinergic Agent Mixture (CAM + SOC). Both groups received their treatment for a total of 14 days. The duration of symptoms was compared across the 14-day period.

Results:

This study found statistically significant reductions in symptom duration for 5 out of 10 symptoms, including dyspnea (reduction of 4.43 days [95% CI: 2.70 ; 6.15], p <0.0001), cough (reduction of 3.18 days [95% CI: 1.29 ; 5.06],  p=0.0089), cephalea (reduction of 3.13 days [95% CI: 1.53 ; 4.72], p= 0.0019), muscle fatigue (reduction of 4.18 days [95% CI: 2.03 ; 6.32], p=0.0019) and general malaise (reduction of 5.98 days [95% CI: 4.20 ; 7.76],  p <0.0001).The study found no significant reductions in the duration of the following symptoms: fever, ageusia, anosmia, chest tightness, and nasal congestion.

Conclusion: 

In comparison to the control group, the intervention group witnessed statistically significant and clinically relevant reductions in the duration of 5 out of 10 common COVID-19 disease symptoms within two weeks. 

This includes a reduction of approximately 4.4 days in the duration of dyspnea, a symptom that appears to be strongly correlated to severe COVID-19 disease and admission to Intensive Care Units.

Further studies are needed to confirm these preliminary findings and to evaluate whether this specific nicotinic cholinergic agonists mixture could have implications for public health.
Best Practice: A Video Mediated Teaching of Phonology
Authors: M.Pd. Drs. Musta’in, , M.Pd. Wildan Isna Asyhar,
Published: September 2021

A narrative inquiry as the approach of qualitative research is conducted in this research to know how the implementation of a video as a teaching media of Phonology and what the problems that the students face in using a video as the learning media of Phonology. This research involves 28 students of the second grade. The subject of research is the students of an English department in Education of UNISKA Kediri. The result is that there are four categorized problems that students face. Students felt that; (1) a native speaker in the video speaks too fast; (2) the pronunciation is unclear; (3) there are some new words or terms; (4) it is difficult to imitate the intonation and stressing of a word and sentence. However, the students can solve problems. Besides that, they get some advantages their ability in some aspects and are aware of the current issue; (1) the first is that the video is easy accessible; (2) the second one is that the video also is appropriate with the current issue so the students, beside learn about phonology, also aware of the current issue; (3) the other one is the students can learn and practice whenever with (out) the guidance of the lecturer; (4) the last advantage that we can offer is the students can listen the native speaker easily because they can play back the video when they cannot catch the word or meaning.
Pengaruh Biaya Diklat, Jumlah Kantor, dan Jumlah Tenaga Kerja pada Laba Perbankan Syariah
Authors: Hastasari Ratih , Suharini Suharini
Published: September 2021

This paper analyzes how significant the internal company factors affecting the profit of the sharia banking industry. There are so many variables that can affecting profit, and profit is an important part of shariah banking for its business sustainability, so in this research, profit was selected as the dependent variable, its data was taken from monthly reports of sharia banking profit/Loss, the independent variables that were selected are the cost of education and training, the number of sharia banking offices, and the amount of the sharia banking labor. This research using 25 data starting from January 2018 to January 2020 with the results of the regression analysis indicates the difference of significance, the cost of training and education significantly affecting the profit of sharia banking, while the results of regression for the number of the office and the amount of labor indicates that both variables were not significantly affecting the profit of sharia banking.
Evaluasi Efisiensi Sektor Ekonomi Kreatif pada Wirausaha Muda di Sekolah Tinggi Ilmu Ekonomi
Authors: Primatami Anggraita , Primadhita Yuridistya
Published: September 2021

The creative economy is an economic sector that results from the development of creativity and ideas. Young entrepreneurs contribute to the improvement of the creative economy sector because they are considered easier to adapt technology, respond to market changes, and think creatively and innovatively. This study aims to evaluate the efficiency of the creative economy sector in entrepreneur students of the College of Economics (STIE). This study used the primary data of 50 entrepreneur students. The research was conducted using the Data Envelopment Analysis (DEA) method by analyzing the input to the output factors. The results showed that 7 out of 50 businesses run by STIE students reached 100% efficiency in January and February. Meanwhile, in March there were 9 businesses that achieved 100% efficiency. As many as 41 businesses have never reached 100% efficiency during January to March 2020. Efficiency improvements for inefficient businesses are carried out by referring to businesses that have been efficient by reducing production costs which include reducing the total cost of labor or raw materials.
Bagaimana Meningkatkan Kinerja Karyawan Perusahaan Logistik? Studi pada PT. JNE Cabang Kota Malang
Authors: Yogatama Ahmad Nizar , Erwiningtyas Mutiara
Published: September 2021

Seiring dengan meningkatnya kebutuhan logistik dalam negeri terutama di Kota Malang, kinerja perusahaan logistik menjadi penting, terutama PT. JNE Cabang Kota Malang. Sebagai perusahaan jasa, maka pelayanan terbaik terhadap konsumen menjadi kunci kinerja karyawan yang juga bagian dari kinerja perusahaan. Kinerja karyawan dapat ditingkatkan melalui kompensasi dan motivasi kerja. Penelitian ini menggunakan teknik sampel proporsional di seluruh divisi perusahaan dengan total sebanyak 81 karyawan yang diuji menggunakan teknik analisa regresi linier berganda. Hasil penelitian ini menyatakan bahwa kompensasi dan motivasi kerja berpengaruh signifikan terhadap kinerja karyawan.
Analisis Pengambilan Keputusan Strategi Bisnis dalam Meningkatkan Penjualan Pada Usaha Langgang
Authors: Redaputri Appin Purisky , Alfarizi Dion
Published: September 2021

Abstract

Kemplang Tunu (panggang) is one of the typical snack products from South Sumatra that is very popular by the community. Langgang's business is a new roast camper business established in June 2020.This research on business actors is a first step strategy in business development do that it can last in the long term, this triggers researchers to find out what alternative strategies are in accordance with Langgang's efforts in increasing sales. This research uses descriptive qualitative with Soft Systems Methodology (SSM) and Analytical Hierarchy Process (AHP) method and Expert Choice application as a tool in processing data supporting system decision making. The results of this study showed that internal factors four sub-criteria and external factors four sub-criteria. The results of the decision-making model using Analytical Hierarchy Process (AHP) stated that the alternative business strategy in Langgang business is the development of a new type of taste with an assessment of (0.387), sales via e-commerce with an assessment of (0.290), opening oulet with an assessment of (0.192) and selection of suppliers with an assessment of (0.131).

 

Keywords: Kemplang Panggang, Decision Making, Business Strategy, Analytical Hierarchy Process (AHP), Expert Choice

 

Abstrak

Kempang Tunu (Panggang) ialah produk olahan istimewa dari Sumatera Selatan dan sangat digemari oleh masyarakat. Usaha Langgang ialah usaha kemplang panggang yang baru didirikan pada bulan Juni 2020. Penelitian pelaku usaha ini merupakan strategi langkah awal pada pengembangan usaha hingga mencapai bertahan sampai jangka panjang, hal ini memicu peneliti untuk mencari tahu alternatif strategi apa yang sesuai dengan usaha Langgang dalam meningkatkan penjualan. Penelitian ini menggunakan kualitatif dekriptif dengan Soft Systems Methodology (SSM) dan metode Analytical Hierarchy Process (AHP) serta aplikasi Expert Choice sebagai alat dalam mengolah data sistem penunjang pengambilan keputusan. Hasil Penelitian ini menunjukkan bahwa faktor internal terdapat empat sub-kriteria dan faktor eksternal terdapat empat sub-kriteria. Hasil model pengambilan keputusan dengan menggunakan Analytical Hierarchy Process (AHP) menyatakan bahwa alternatif strategi bisnis pada usaha Langgang yaitu pengembangan jenis rasa baru dengan penilaian sebesar (0,387), penjualan via e-commerce dengan penilaian sebesar (0,290), membuka oulet dengan penilaian sebesar (0,192) dan pemilihan supplier dengan penilaian sebesar (0,131).

 

Kata kunci: Kemplang Panggang, Pengambilan Keputusan, Strategi Bisnis, Analytical Hierarchy Process (AHP), Expert Choice