bluuebunny/crossref_metadata_2025 huggingface dataset:
DNA sequence features underlying large-scale duplications and deletions in human
Authors: Kołomański Mateusz , Szyda Joanna , Frąszczak Magdalena , Mielczarek Magda
Published: April 2021

BackgroundCopy Number Variants (CNVs) may cover up to 12% of the whole genome and have substantial impact on phenotypes. We used 5 867 duplications and 33 181 deletions available from the 1000 Genomes Project to characterize genomic regions vulnerable to CNV formation and to identify sequence features characteristic for those regions.ResultsOnly 14 CNVs contained unknown nucleotides, which reflected the high quality of the analysed data. The GC content for deletions was lower and for duplications was higher than for randomly selected regions. In regions flanking deletions and downstream of duplications content was higher than in the random sequences, but upstream of duplication content was lower. In duplications, the percentage of low complexity sequences was not different from the randomized data, but in deletions it was higher. Moreover, it was significantly higher upstream of CNVs as compared to random sequences. Conversely, it was lower downstream of duplications. The majority of CNVs intersected with genic regions - mainly with introns. ConclusionsGC content may be associated with CNV formation and CNVs, especially duplications are initiated in low complexity regions. Moreover, CNVs located or overlapped with introns indicate their role in shaping intron variability. Genic CNV regions were enriched in many essential biological processes such as cell adhesion, synaptic transmission, transport, cytoskeleton organization, immune response and metabolic mechanisms what indicates that this large-scaled variants play important biological roles.
Suboptimal Therapy Following Breast Conserving Surgery in Triple Negative and HER2-Postive Breast Cancer Patients
Authors: Johnson Jeffrey E. , Strassle Paula D , Oliveira Guilherme C de , Agala Chris B. , Spanheimer Philip M. , Gallagher Kristalyn K , Ollila David W. , Muss Hyman B. , Downs-Canner Stephanie M
Published: April 2021

Purpose To assess potential disparities in guideline-concordant care delivery among women with early stage triple-negative and HER2-positive breast cancer treated with breast conserving therapy. Methods Women ≥40 years old diagnosed with pT2N0M0 triple-negative or HER2-positive breast cancer treated with primary surgery and axillary staging between 2012 and 2017 were identified using the National Cancer Database (NCDB). The primary outcome was receipt of adjuvant systemic therapy and radiation concordant with current guidelines. Multivariable log binomial regression was used to assess the prevalence of optimal therapy use across patient and cancer characteristics. Kaplan-Meier curves were used to assess 5-year overall survival. Multivariable Cox proportional hazards regression was used to compare the impact of optimal therapy on 5-year mortality. Results 11,785 women were included with 7,843 receiving optimal therapy. Receipt of optimal therapy decreased with age even after adjusting for comorbidities and cancer characteristics; other sociodemographic factors were not associated with differences in receipt of optimal therapy. Among patients who did not receive adjuvant systemic therapy, most were not offered the treatment (49%) or refused (40%). Overall 5-year survival was higher among women who received optimal therapy (89% [95% CI 88.0-89.3] vs. 66% [95% CI 62.9-68.5]). Patients who received suboptimal therapy were over twice as likely to die within 5-years of their diagnosis (adjusted HR 2.44, 95% CI 2.12-2.82). Conclusion Age is the primary determinant of the likelihood of a woman to receive optimal adjuvant therapies in high-risk early stage breast cancer. Patients who did not receive optimal therapy had significantly diminished survival.
Performance Analysis of Crosstalk Subcarrier Multiplexing and Wave Division Multiplexing in Optical Communication System
Authors: Elsayed Ebrahim E.
Published: April 2021

In traditional optical communication, duplexity is achieved by using two fibers, each having a transmitter and a receiver. Economically, bidirectional wavelength division multiplexing (WDM) transmission systems utilizing a single fiber will be more attractive not only reducing the use of the fiber by a factor of two, but also the number of components. Duplex transmissions over a single fiber can double the capacity of an installed unidirectional link. The idea of this paper is to study another approach using the subcarrier multiplexing (SCM)-based optical network and evaluate the physical transmission quality of analog and digital signal using SCM approach and the characteristic of fiber nonlinear crosstalk such as stimulated Raman scattering, Cross phase modulation and four-wave mixing in the SCM externally modulation optical link. A suitable bandwidth of 890 – 950 MHz is selected for subcarriers and channel bandwidth of 200 KHz and carrier. By measuring the optical bit interference (OBI) performance limitations of the subcarrier multiplexing WDM optical transmission system is investigated. The OBI for 10 channels for input power 1 dB is -40 dB whereas for 110 channels the OBI is -20 dB separation of 250 KHz are considered.
Impact of thymic epithelial primary cilia on T cell development
Authors: Kutomi Osamu , Nonaka Shigenori , Hozumi Katsuto , Takeda Sen
Published: April 2021

Primary cilia are ubiquitous hair-like organelles, usually projecting from the apical cell surface. They are essential for the organogenesis and homeostasis of various physiological functions, and their dysfunction leads to a plethora of human diseases. However, there are few reports on the role of primary cilia in the immune system; therefore, we focused on their role in the thymus that nurtures immature lymphocytes to full-fledged T cells. After detecting primary cilia on the thymic epithelial cell (TEC) expressed transforming growth factor β (TGF-β) receptor in the basal body, we established a line of an intraflagellar transport protein 88 (Ift88) knockout mice lacking primary cilia in TECs (Ift88 TEC null mutant) to clarify their precise role in thymic organogenesis and T cell differentiation. The Ift88-TEC null mutant mice showed stunted cilia or lack of cilia in TECs. The intercellular contact between T cells and the “thymic synapse” of medullary TECs was slightly disorganized in Ift88-TEC null mutants. Notably, the CD4- and CD8-single positive thymocyte subsets increased significantly. The absence or disorganization of thymic cilia downregulated the TGF-β signaling cascade, increasing the number of single positive thymocytes.
Co3O4-Bi2O3 heterojunction; An effective photocatalyst for photodegradation of rhodamine B dye
Authors: Saeed Muhammad , Baig Afifa , Jamal Muhammad Asghar , Akram Nadia , Bokhari Tanveer Hussain
Published: April 2021

Recently, the research on development of visible-light-active photocatalysts for photodegradation of organic pollutants has got much attention. Therefore, this study reports the synthesis of Co3O4-Bi2O3 heterojunction as visible-light responsive photocatalyst for photodegradation of rhodamine B dye. The Co3O4-Bi2O3 heterojunction was synthesized by coprecipitation method and characterized by XRD, EDS, SEM, TGA and FTIR. The as prepared Co3O4-Bi2O3 heterojunction was utilized as photocatalyst for photodegradation of rhodamine B dye using a 100 mg/L solution. It was observed that Co3O4-Bi2O3 showed best catalytic performance with ~ 92% degradation of rhodamine B dye than Co3O4 and Bi2O3 with 14 and 34% removal of rhodamine B dye, respectively. The rate constant for Co3O4-Bi2O3 catalyzed photodegradation of rhodamine B was 6 times and 3 times higher than rate constant for Co3O4 catalyzed and Bi2O3 catalyzed photodegradation of rhodamine B, respectively. The pH 8 was found as optimum pH for Co3O4-Bi2O3 catalyzed photodegradation of rhodamine B dye.
Assessing the risk factors of under-five deaths in rural parts of Ethiopia
Authors: Mihret Yenew Alemu
Published: April 2021

Background of the study: Under-five mortality is the likelihood for a child born alive to die between birth and fifth birth day. Mortality under the age of five has been the main problem in public health policies especially in rural parts of Ethiopia.Objective: The objective of this study was to assess the risk factors of under-five mortality in Ethiopia using the 2011 EDHS data. Results: Information from 8,668 women included in the study show that 64.5% of the women never experienced under-five deaths of their children. Among four possible count models considered, the ZINB regression model was selected as the most appropriate model. Conclusion: The study revealed that mother’s age first birth, breastfeeding status, wealth index, whether the mother is currently working, region and mother’s level of education had statistically significant association with the number of under-five deaths in rural parts of Ethiopia.
Dynamic Changes in Endogenous Hormones in Terminal Buds from Different Crown Positions in Sequoia sempervirens (Lamb.) Endl
Authors: Ju Shuming , Ji Lingzhen , Xu Delan
Published: April 2021

Endogenous hormones can improve plant resistance and regulate growth and development. To obtain the basis of chemical control technology for improving Sequoia sempervirens resistance in Xuzhou, China, the current study probed the dynamic changes of endogenous hormones in terminal buds from different crown positions in S. sempervirens. Enzyme-linked immunosorbent assay (ELISA) was used to measure changes in the contents of endogenous hormones in terminal buds from the upper, middle, and lower lateral branches. The results were as follows: Indole acetic acid (IAA) in all terminal positions had a similar change trend of “rise–drop–rise.” Gibberellic acid (GA) in the upper and middle terminal buds showed similar trends of “drop–rise,” but GA in the lower lateral branches presented a “rise–drop” trend. Zeatin–riboside (ZR) in all terminal positions had similar change trends of “drop–rise.” Abscisic acid (ABA) in all terminal positions had similar change trends of “drop–rise–drop.” the trend of (IAA + GA + ZR)/ABA in all terminal positions was the same as that of IAA. Our results confirmed that, in autumn, the high content and ratio of stimulatory endogenous hormones in the terminal bud of S. sempervirens induced the terminal bud cells to continue to divide and grow, and the new branches could not be fully lignified and deeply dormant before the onset of low temperatures in winter, which led to a decrease in cold resistance and even the death of the terminal buds.
Josephson oscillations in split one-dimensional Bose gases
Authors: van Nieuwkerk Yuri Daniel , Schmiedmayer Jörg , Essler Fabian
Published: April 2021

We consider the non-equilibrium dynamics of a weakly interacting Bose gas tightly confined to a highly elongated double well potential. We use a self-consistent time-dependent Hartree--Fock approximation in combination with a projection of the full three-dimensional theory to several coupled one-dimensional channels. This allows us to model the time-dependent splitting and phase imprinting of a gas initially confined to a single quasi one-dimensional potential well and obtain a microscopic description of the ensuing damped Josephson oscillations.
Bulk-boundary-defect correspondence at disclinations in rotation-symmetric topological insulators and superconductors
Authors: Geier Max , Fulga Ion Cosma , Lau Alexander
Published: April 2021

We study a link between the ground-state topology and the topology of the lattice via the presence of anomalous states at disclinations -- topological lattice defects that violate a rotation symmetry only locally.
We first show the existence of anomalous disclination states, such as Majorana zero-modes or helical electronic states, in second-order topological phases by means of Volterra processes.
Using the framework of topological crystals to construct d-dimensional crystalline topological phases with rotation and translation symmetry, we then identify all contributions to (d-2)-dimensional anomalous disclination states from weak and first-order topological phases.
We perform this procedure for all Cartan symmetry classes of topological insulators and superconductors in two and three dimensions and determine whether the correspondence between bulk topology, boundary signatures, and disclination anomaly is unique.
Monitoring the financial security of the Ukrainian banking sector in the context of system-deterministic challenges
Authors: Yasynska Nadiia , Syrmamiikh Iryna , Penez Oksana
Published: April 2021

The development of the financial market and the transformation of the banking sector create a need for diagnostics of its financial security. This study is aimed at determining the level of the Ukrainian banking sector financial security in the event of decapitalization of the national economy. The paper uses multicomponent and behavioral analysis methods. The empirical study is based on Ukrainian data for 37 indicators by three components (for multicomponent analysis) and 23 indicators (for behavioral analysis). The study presents an improved algorithm for monitoring the level of Ukrainian banking sector’s financial security based on the calculation of the integral indicator. Only the system of “Financial results” indicators as the most significant component has relative independence from the other two components (“Financial stability” and “Macroeconomic stability”). According to assessments, in 2008–2017 Ukrainian banking sector’s financial security was 0,485-0,539; and in 2018 it became 0,626. The behavioral analysis of the partial integral indicator of the “Financial stability” component with the withdrawn assets located in offshore jurisdictions revealed the causal relation of the negative impact of capital outflow on the financial stability of the banking sector. This study has a practical value for determining the level of the banking sector financial security.
Mediastinal teratoma in a second trimester fetus
Authors: I.V. Novikova, E.I. Marakhovskaya, A.M. Sakharchuk et all
Published: April 2021

А case of a large mediastinal teratoma in a fetus with a large pleural effusion at 21 weeks of gestation is
presented. Detailed sonographic examination showed a large, complex cystic and solid mass posterior to the
sternum, in the upper anterior mediastinum, measuring 35 31 22 mm. The lungs were visualized without
morphological changes or pulmonary arterial tree abnormalities, but they were relatively small. The couple
opted for pregnancy termination at 23 weeks of gestation. Histological examination revealed an encapsulated
immature teratoma.
A case of prenatal diagnosis of anterior meningocele in the fetus
Authors: T.I. Nagoeva
Published: April 2021

For the first time in the domestic literature, a description of a case of anterior meningocele detected at
38–39 weeks of gestation is presented. After birth the prenatal diagnosis was confirmed by magnetic resonance
imaging.
Agro-Industrial Waste Valorization: Transformation of Starch from Mango Kernel into Biocompatible, Thermoresponsive and High Swelling Nanogels
Authors: de Oliveira Marlizia , Madruga Liszt , de Lima Bruna , Villetti Marcos , de Souza Filho Men , Kipper Matt , Marques Nívia , Balaban Rosangela
Published: April 2021

Mango industry processing disposes 40-60% of this fruit as residues, such as peels and kernels. The exploration of bioproducts from these industrial rejects can reduce environmental impact besides of producing high value-added materials. In this scenario, carboxymethyl starch nanoparticles were produced from mango (Mangifera indica L.) kernel starch. These nanoparticles were then decorated with thermoresponsive chains of the amino terminated poly(N-isopropylacrylamide) (PNIPAM‑NH2), with the intention of evaluating their applicability in the biomedical area. Elemental analysis, Fourier transform infrared (FTIR) and 1H nuclear magnetic resonance (NMR) spectroscopy confirmed successful grafting of PNIPAM-NH2 onto the carboxymethyl starch backbone. Scanning electron microscopy (SEM) images and dynamic light scattering (DLS) data showed sizes of 100 and 112 nm in the dry state and of 744 and 598 nm in the hydrated state, when the grafting degree (GD) was of 6 and 14.3%, respectively. The degree of swelling was of 41,100 and 15,100% for GD of 6 and 14.3% respectively, suggesting that the nanogels are suitable for drug incorporation. The toxicity of the nanogels to human adipose-derived stem cells (ADSCs) and red blood cells (RBCs) was evaluated by lactate dehydrogenase (LDH), alamarBlue and hemolysis assays. Both nanogels were non-cytotoxic and non-hemolytic, suggesting the suitability of these biomaterials for cell- and blood-contacting applications.
Access to Essential Contraception, Family Planning, and Safe Motherhood Services During COVID-19 Pandemic: Single Secondary Level Care Hospital Experience
Authors: Biswas Jayanta Kumar , Poddar Soumen Das , Saravagi Ganesh , Nilakantan Ajith
Published: April 2021

OBJECTIVE: During the COVID-19 pandemic, more precisely as a result of restrictions on movement and continuing altered perception of essential health care services, women’s health is disproportionately affected due to reduced access to services as per reports and statements made by different global and national level Government and non-government agencies. We aimed to evaluate the health care impacts related to contraception, family planning, and safe motherhood in an Indian Armed Forces secondary level care hospital during the COVID-19 pandemic.
STUDY DESIGN: Immediate health care effect on women’s sexual and reproductive life during pandemic months (April to August of the year 2020) is analyzed through a retrospective observational cohort study in a single Indian Armed Forces secondary level care hospital experience.
RESULTS: It has shown more late reported unintended pregnancies requiring surgical intervention, more late-registered antenatal cases and consequently delayed essential evaluations, increased trend in high-risk cases requiring in-patient care (IPD), and reduced access to contraception and family planning services in comparison to those in the previous two years.
CONCLUSION: Considering these negative impacts noted in this observation, with the help of policymakers, government, and other non-government agencies, all services should be made available to women including un-interrupted out-patient (OPD) and IPD services in all hospitals, along with continued basic infection prevention and control precautions (IPC) to both clientele and health care workers (HCW). Telemedicine can also play a supplementary role in various aspects of women’s health to avoid upcoming population explosion and for better maternal-child health care.
Kovid-19 Pandemi Döneminde Uzaktan Eğitimde Öğretim Elemanlarının Öz-yansıtma ve Öz-Düzenleme Deneyimleri ve Uygulamaları
Authors: TAKKAÇ TULGAR Ayşegül
Published: April 2021

Uzaktan eğitimde öğretim elemanı algıları ve deneyimleri küresel bağlamda sürekli artan bir ilgi çekmektedir. Ancak, uzaktan eğitimde öğretim elemanlarının öz-yansıtma ve öz-düzenleme deneyimleri konusunda yeterli araştırma bulunmamaktadır. Bu betimleyici durum çalışması Kovid-19 pandemi döneminde Türkiye’de bir devlet üniversitesinde zorunlu olarak uzaktan eğitim dersleri yürüten öğretim elemanlarının öz-yansıtma ve öz-düzenleme deneyimlerini araştırmayı amaçlamaktadır. Katılımcılar Türkçe Öğretim Merkezi’nde uluslararası öğrencilere Türkçe öğreten dört öğretim elemanından oluşmaktadır. Veriler katılımcıların yapılandırılmamış yansıtma notları ve açık-uçlu sorulara verdikleri cevaplar yoluyla toplanmıştır. Geleneksel içerik analizinin sonuçları katılımcıların öz-yansıtma ve öz-düzenleme deneyimlerini ve uygulamalarını etkileyen üç boyut ortaya koymuştur: uzaktan eğitime uyum, iletişimsel modeller ve öğretim uygulamaları. Sonuçlar dikkate alınarak bazı pedagojik önerilerde bulunulmuştur.
Riesgo de mercado en Portafolios mexicanos previo a la crisis COVID-19: Portafolio de renta fija vs Portafolio de capital
Authors: Agudelo Torres Gabriel Alberto , Olivares Aguayo Héctor Alonso , Téllez Pérez Julio
Published: April 2021

El objetivo de la investigación es mostrar las ventajas que tienen las inversiones en Portafolios de renta fija respecto a los de capital en el periodo de estudio. Se realiza un comparativo de ambos Portafolios de enero 2017 a mayo 2019, teniendo como métrica el VaR paramétrico al 99.9% de confianza para cada Portafolio. Los resultados, muestran que el inversionista obtiene una mayor cantidad de ganancias ($9,778.14) en el Portafolio de renta fija al invertir $1,000,000 a 28 días, por lo que previo a la crisis COVID-19 se observa que fue viable invertir en este tipo de Portafolio. Como limitación se asumen rendimientos gaussianos. El trabajo es original porque con datos reales del mercado mexicano empíricamente se muestra que previamente al periodo de crisis COVID-19 el Portafolio de renta fija fue mejor en rendimientos que los Portafolios de capitales. Finalmente se concluye que hoy en día lo anterior no ocurre, debido a la gran caída que han tenido las tasas de referencia en México derivada de la crisis sanitaria COVID-19, incluso se vislumbran a la brevedad tasas reales negativas.
Deep Learning Application for Vocal Fold Disease Prediction Through Voice Recognition: Preliminary Development Study
Authors: Hu Hao-Chun , Chang Shyue-Yih , Wang Chuen-Heng , Li Kai-Jun , Cho Hsiao-Yun , Chen Yi-Ting , Lu Chang-Jung , Tsai Tzu-Pei , Lee Oscar Kuang-Sheng
Published: April 2021

Background

Dysphonia influences the quality of life by interfering with communication. However, a laryngoscopic examination is expensive and not readily accessible in primary care units. Experienced laryngologists are required to achieve an accurate diagnosis.

Objective

This study sought to detect various vocal fold diseases through pathological voice recognition using artificial intelligence.

Methods

We collected 189 normal voice samples and 552 samples of individuals with voice disorders, including vocal atrophy (n=224), unilateral vocal paralysis (n=50), organic vocal fold lesions (n=248), and adductor spasmodic dysphonia (n=30). The 741 samples were divided into 2 sets: 593 samples as the training set and 148 samples as the testing set. A convolutional neural network approach was applied to train the model, and findings were compared with those of human specialists.

Results

The convolutional neural network model achieved a sensitivity of 0.66, a specificity of 0.91, and an overall accuracy of 66.9% for distinguishing normal voice, vocal atrophy, unilateral vocal paralysis, organic vocal fold lesions, and adductor spasmodic dysphonia. Compared with the accuracy of human specialists, the overall accuracy rates were 60.1% and 56.1% for the 2 laryngologists and 51.4% and 43.2% for the 2 general ear, nose, and throat doctors.

Conclusions

Voice alone could be used for common vocal fold disease recognition through a deep learning approach after training with our Mandarin pathological voice database. This approach involving artificial intelligence could be clinically useful for screening general vocal fold disease using the voice. The approach includes a quick survey and a general health examination. It can be applied during telemedicine in areas with primary care units lacking laryngoscopic abilities. It could support physicians when prescreening cases by allowing for invasive examinations to be performed only for cases involving problems with automatic recognition or listening and for professional analyses of other clinical examination results that reveal doubts about the presence of pathologies.
Integrated Prevention at Work: Protocol for a Concept Analysis
Authors: Lecours Alexandra , Major Marie-Ève , Vincent Claude , Lederer Valérie , Lamontagne Marie-Ève
Published: April 2021

Background

Integrated prevention at work promises to eliminate the boundaries between primary, secondary, and tertiary prevention actions taken by stakeholders in the world of work. It is receiving increasing attention from the scientific community because of its concerted and harmonized approach, which promotes employment access, return, and healthy long-term continuation. Although promising, integrated prevention is not yet well-defined, which makes it difficult to operationalize.

Objective

This manuscript exposes the protocol of a study aiming to conceptualize integrated prevention at work on the basis of scientific and experiential knowledge.

Methods

Using a concept analysis research design, data collection has been planned in 2 parts. A meta-narrative literature review will first be conducted to document how integrated prevention has been defined in the literature. Then, phone interviews will be conducted with key informers (ie, managers, workers, ergonomists, occupational therapists, psychologists, physiotherapists, union and insurance representatives) to document their viewpoints and understanding of integrated prevention at work. Qualitative data gathered during these 2 parts of research will be analyzed using template analysis, which allows data from literature and empirical collection to be analyzed simultaneously. The analysis will bring out the points of convergence, divergence, and complementarity between the information gleaned from literature and key informers’ experiences to arrive at a conceptualization of integrated prevention at work by identifying its uses, attributes, antecedents, and consequences. As a final step, validation and interpretation with a TRIAGE (Technique for Research of Information by Animation of a Group of Experts) group will be carried out in collaboration with the key informers to identify the tools for the implementation of integrated prevention at work and promote workers’ health and safety.

Results

This study is expected to offer a contemporary conceptualization of integrated prevention at work that clearly lays out the variables of this concept and elicits the viewpoints of the different stakeholders.

Conclusions

This study will contribute to the advancement of knowledge about the professional injury prevention continuum. The clear identification of the uses, attributes, antecedents, and consequences of integrated prevention at work will offer concrete tools to stakeholders to implement innovative and promising approaches to integrated prevention at work.

International Registered Report Identifier (IRRID)

PRR1-10.2196/29869
Provider-initiated HIV testing in Puerto Rico: Data from NHBS-HET cycle 2016 (Preprint)
Authors: Colón-López Vivian , Canario De La Torre Maureen M , Centeno Nadia , Agudelo Ivony Y , Rolón Colón Yadira , Miranda Sandra , Pabón Maria , Rodriguez Lebrón Jorge , Girona Gladys
Published: April 2021

BACKGROUND

According to CDC and WHO guidelines, all individuals from 13 to 64 years of age should get screened for HIV infection as part of their routine medical examinations, and individuals at high risk should get tested annually.

OBJECTIVE

This study aimed to identify sociodemographic, healthcare, and sexual behavior predictors of provider-initiated HIV testing (PIHT) using data from the Puerto Rico National HIV Behavioral Surveillance (PR-NHBS) 2016 cycle; directed towards heterosexuals at increased risk of HIV infection (HET).

METHODS

A total sample of 531 eligible participants were recruited through respondent-driven sampling (RDS), where sociodemographic characteristics, healthcare utilization, and HIV testing were assessed.

RESULTS

Despite 72% showed high-risk sexual behavioral practices and 65.2% of the HET sample interviewed reported a low perceived risk of HIV infection, only 19% reported not receiving an HIV test offered at a recent medical visit. Multivariate analysis shows that HET who engaged in high-risk sexual behaviors (AOR = 0.52; 95% CI: 0.30–0.90) were less likely to receive HIV-test offers from their providers.

CONCLUSIONS

This study further emphasizes the need for healthcare providers to follow recommended guidelines for HIV testing in healthcare settings as a means of establishing preventive measures to further counteract the HIV epidemic in Puerto Rico, specifically among HET.
Making Meaning of Religious Values in Preventing a Fatal Suicide Act of a Bisexual Youth with Borderline Personality Disorder: A Qualitative Study
Authors: Valentina Tience Debora , Marchira Carla R , Afiatin Tina , Hadjam Noor R
Published: April 2021

Male adolescents of sexual minority groups often present mental health problems and suicidal behaviors. This qualitative study was conducted to explore how a bisexual youth with borderline personality disorder and multiple suicide attempts coped with his intention to die. Analysis was done using the Grounded Theory approach resulted in several themes. First, the pathway to suicidal behaviors; depicting the conflict between parents and the history of mother’s suicide attempts made him felt disconnected with the family. Second, the feeling of not deserving loved although having the need to be loved and to love. Third, the ambivalence of his sexual orientations as he had strong desire to be with a man yet felt happy dating a girl. Fourth, the interpretation of religious values for preventing fatal suicidal act. He perceived that his suicide attempts failed because God wants him to stay alive. The discussion addresses the aspect of religiosity that obstructs suicidal behaviors in bisexual youths
POSTCOLONIAL TRANSLATION STUDIES: FOREIGNIZATION AND DOMESTICATION OF CULTURE-SPECIFIC ITEMS IN OF MICE AND MEN’S INDONESIAN TRANSLATED VERSIONS
Authors: Fitriyantisyam Hafizha , Munandar Aris
Published: April 2021

Resistance to Western Culture can be seen through translator’s strategy of translating novels. This research aims to analyze the translation of culture-specific items in Indonesian translated versions of Of Mice and Men, originally written by John Steinbeck. The selected translated versions belong to the work of Pramoedya Ananta Toer (2003) and Ariyantri E. Tarman (2017). The translations of culture-specific items are analyzed under Transnational American Studies paradigm to find out the dominant translation principle applied in both translated versions and the results are discussed from the perspective of postcolonial translation studies. From the data, it is found out that the domestication principle is more dominant than foreignization strategy. Analyzed from postcolonial translation studies, the tendency to use the domestication principle in translated novels show the efforts of the target culture to fight against Western culture as the source culture. Although both Indonesian versions of Of Mice and Men mostly apply the domestication principle, the recent translated version (T2) shows an increase in the use of foreignization principle in which English loanwords are frequently used. From a postcolonial translation studies’ perspective, it can be concluded that target culture is against Western culture; however, the signs of cultural imperialism, especially linguistic imperialism, have grown in the recent years.
BOAZ HAGIN’S PHILOSOPHY OF DEATH AS REFLECTED IN THE HUNGER GAMES TRILOGY FILMS
Authors: Nurjanah Hidayatul
Published: April 2021

The Hunger Games is one of Hollywood films that contains deaths and deadly scenes throughout its trilogy. There are plenteous meanings of deaths that can be analyzed from the films, which will develop new meanings and definitions of deaths as an interesting topic to discuss. The researcher employed Boaz Hagin's framework of death because Hagin provides a framework about deaths and how deaths can be meaningful. In his book, he writes a broader range of philosophical description about deaths in Classical Hollywood Cinema which explores the morality and ethical values of mainstream films that portrays death as a meaningful part of life. The research problem is what is the meaning of deaths found in Hunger Games using Hagin’s framework of deaths. This research was conducted using a descriptive qualitative approach aiming at describing the phenomenon and characteristics. The data collected qualitatively by examining them throughout to get relevant issues and ideas and classify them. The findings show that death can bring meanings to characters in the films, such as a death in line where death means as a savior for their beloved ones, death as politic seen from the characters' past life that brings hope for the future, death as the Access, Authority, and Test, can be seen from how the characters use their talent to survive.
Optimising the Business and Talent Environment in Chengdu to Help High-quality Economic Development
Authors: Xiang Li , Hongxi Chen
Published: April 2021

This paper selects the time series data of Chengdu city from 2009 to 2018, refers to the existing literature, constructs an econometric model for empirical research, uses Eviews software to conduct regression analysis and model testing, and selects the data of its representative variables from the three perspectives of the construction of business talent environment (policy environment, talent attractiveness, and ecological livability level) to conduct an empirical study on the relationship between business talent environment and The results show that: the financial expenditure on social security and employment The results show that social security and employment expenditure, average annual wage and green space in Chengdu, as important factors influencing the construction of business and talent environment, have a significant effect on the high-quality economic development of Chengdu.
Politics of choice- deconstructing the idea of marriage
Authors: Chowdhury Arpita
Published: April 2021

In this paper, I have attempted to talk about the idea of marriage largely based on three different texts that are ‘Marriages are Made by Eunice D’souza, ‘Exercise Book’ by Rabindranath Tagore and ‘Kallu’ by Ismat Chugtai. The constant subjugation of the female voice is examined through various shreds of evidence. It is quite apparent that women have hardly a say in choosing their life partner and it’s the overarching dominance of the family to which the girls have to succumb. In ‘Marriages are made’ by Eunice D’souza we see the complete dehumanization of a woman who is reduced to a mere product. Tagore in ‘Exercise Book’ attempts to enquire the prospects of child marriage whereas in Ismat Chugtai’s ‘Kallu’ we see the muted gender. Hence, we will see the ways in which authors bring to fore the idea of power struggles in the gendered narrative.
Scaling by Optimising: Modularisation of Data Curation Services in Growing Organisations
Authors: Peukert Hagen
Published: April 2021

After a century of theorising and applying management practices, we are in the middle of entering a new stage in management science: digital management. The management of digital data submerges in traditional functions of management and, at the same time, continues to recreate viable solutions and conceptualisations in its established fields, e.g. research data management. Yet, one can observe bilateral synergies and mutual enrichment of traditional and data management practices in all fields. The paper at hand addresses a case in point, in which new and old management practices amalgamate to meet a steadily, in part characterised by leaps and bounds, increasing demand of data curation services in academic institutions. The idea of modularisation, as known from software engineering, is applied to data curation workflows so that economies of scale and scope can be used. While scaling refers to both management science and data science, optimising is understood in the traditional managerial sense, that is, with respect to the cost function. By means of a situation analysis describing how data curation services were applied from one department to the entire institution and an analysis of the factors of influence, a method of modularisation is outlined that converges to an optimal state of curation workflows.
Assessment, Usability, and Sociocultural Impacts of DataONE
Authors: Sandusky Robert J. , Allard Suzie , Baird Lynn , Cannon Leah , Crowston Kevin , Forrester Amy , Grant Bruce , Hu Rachael , Olendorf Robert , Pollock Danielle , Specht Alison , Tenopir Carol , Volentine Rachel
Published: April 2021

DataONE, funded from 2009-2019 by the U.S. National Science Foundation, is an early example of a large-scale project that built both a cyberinfrastructure and culture of data discovery, sharing, and reuse. DataONE used a Working Group model, where a diverse group of participants collaborated on targeted research and development activities to achieve broader project goals. This article summarizes the work carried out by two of DataONEâ€™s working groups: Usability & Assessment (2009-2019) and Sociocultural Issues (2009-2014). The activities of these working groups provide a unique longitudinal look at how scientists, librarians, and other key stakeholders engaged in convergence research to identify and analyze practices around research data management through the development of boundary objects, an iterative assessment program, and reflection. Members of the working groups disseminated their findings widely in papers, presentations, and datasets, reaching international audiences through publications in 25 different journals and presentations to over 5,000 people at interdisciplinary venues. The working groups helped inform the DataONE cyberinfrastructure and influenced the evolving data management landscape. By studying working groups over time, the paper also presents lessons learned about the working group model for global large-scale projects that bring together participants from multiple disciplines and communities in convergence research.
docente diseñador
Authors: Flores Zavaleta Cecilia Esperanza , Terbullino Tamashiro Vladimir , Zárate Amador Aldo Renato , Araujo Riva Yolanda Milagros , Figueroa Ocampo Aldo Rafael
Published: April 2021

Esta investigación tuvo como objetivo evaluar la satisfacción y el rendimiento académico de los estudiantes universitarios que participaron en un programa blended de escritura, el cual integró una red social y el sistema de gestión de aprendizaje Blackboard. De acuerdo con el enfoque metodológico de la investigación basada en el diseño (EDR), el programa se sometió a procesos iterativos de análisis, implementación y evaluación durante tres ciclos académicos consecutivos. Para conocer el nivel de satisfacción generado, se empleó una encuesta basada en una escala de Likert. Además, se emplearon las calificaciones y promedios de los estudiantes para obtener datos sobre el rendimiento. Del análisis se concluye que el programa desarrollado alcanza altos índices de satisfacción; no obstante, el rendimiento académico no se incrementó al compararse con la versión presencial del curso.
Universidad pública y discapacidad
Authors: Tenorio Eitel Solange , Ramírez-Burgos María José
Published: April 2021

En Latinoamérica ha aumentado el acceso a la educación superior, sin embargo, este crecimiento ha sido desigual en cuanto a las oportunidades de acceso, participación y finalización de estudios. A partir de diversas políticas orientadas hacia un enfoque inclusivo, se han implementado iniciativas que buscan igualdad y equidad de estudiantes con discapacidad en el nivel terciario. El presente artículo es producto de una revisión bibliográfica de diversos documentos en materia de inclusión de estudiantes con discapacidad, el cual analiza información del caso de Chile y, particularmente, de universidades públicas. El estudio refleja avances en materia legislativa, mismos que han sido insuficientes para eliminar las barreras existentes, tanto materiales como socioculturales. Se plantea la necesidad de un trabajo en red entre las instituciones, que promueva un enfoque de derecho, enfatizando el rol democratizador de la educación estatal.
Consequences of preserving reversibility in quantum superchannels
Authors: Yokojima Wataru , Quintino Marco Túlio , Soeda Akihito , Murao Mio
Published: April 2021

Similarly to quantum states, quantum operations can also be transformed by means of quantum superchannels, also known as process matrices. Quantum superchannels with multiple slots are deterministic transformations which take independent quantum operations as inputs. While they are enforced to respect the laws of quantum mechanics, the use of input operations may lack a definite causal order, and characterizations of general superchannels in terms of quantum objects with a physical implementation have been missing. In this paper, we provide a mathematical characterization for pure superchannels with two slots (also known as bipartite pure processes), which are superchannels preserving the reversibility of quantum operations. We show that the reversibility preserving condition restricts all pure superchannels with two slots to be either a quantum circuit only consisting of unitary operations or a coherent superposition of two unitary quantum circuits where the two input operations are differently ordered. The latter may be seen as a generalization of the quantum switch, allowing a physical interpretation for pure two-slot superchannels. An immediate corollary is that purifiable bipartite processes cannot violate device-independent causal inequalities.
Pemikiran Pendidikan Islam al-Zarnuzi: Analisis Kritis Penghormatan Terhadap Ilmu dan Guru
Authors: Khairuni Nisa
Published: April 2021

A person's moral is reflected in morals. This can be obtained from education, especially Islamic education as al-Zarnuzi's thought is known for his moral messages in his Ta'lim al Muta'allim work, but so far many students have found failures in terms of moral competence, then this paper is discussed using library research that is by searching to collect, read and analyze the research problem in the books. The findings show that learning must intend and have a goal to seek the pleasure of Allah, written, repeated lessons that have been learned, deliberation, Taammul. In addition, al-Zarnuzi also explained some of the requirements in seeking knowledge in order to succeed. The students must be smart, have high curiosity, be patient, have money, listen to the instructions from the teacher, and have time to study. Furthermore, when viewed from the area of ​​time setting and the place where Shaykh al-Zarnuji lived, distance and time stretch between the past and the present. The problem that may occur today that it can be called weakness is that the instruments and tools used to develop education certainly cannot be applied just like that in the present. One example is the role and behavior of respecting teachers. If what al-Zarnuji says is explained exclusively, what ultimately happens is unconditional obedience. This is where future education will lose its significance. So a possible weakness arising from al-Zarnuzi's thought is a textual understanding of his work.
Kompetensi Pedagogik Guru PAI dalam Menyusun Rencana Pelaksanaan Pembelajaran Berbasis Higher Order Thinking Skills
Authors: Rahmah Siti
Published: April 2021

This study aimed to determine the understanding of PAI teachers of SMA Negeri 1 Sigli on the concept of RPS based on HOTS, the pedagogical competence of PAI teachers at SMA Negeri 1 Sigli in preparing HOTS-based Learning Implementation Plans (RPP), and the factors that influence the competence of PAI teachers at SMA Negeri 1 Sigli in compiling HOTS-based RPP. To achieve these objectives, this study uses qualitative research methods. Data collection techniques are done through interviews and document analysis. The subjects of the study were 3 PAI teachers from SMA Negeri 1 Sigli, the Principal of SMA Negeri 1 Sigli, and the Deputy of Priancipal of SMA Negeri 1 Sigli in the curriculum. The results showed that: (1) In general PAI teachers who served in SMA Negeri 1 Sigli had a good understanding of the HOTS-based RPP concept, but one of them was still lacking, this was evident from his doubts in answering questions that the authors asked even there were some questions answered do not know. Besides that, it can also be seen from the discrepancy between the explanation submitted and the compiled lesson plan; (2) The results of the analysis of the Teacher's Learning Implementation Plan (RPP) indicate that the majority of PAI teachers of SMA Negeri 1 Sigli already have good competence in preparing HOTS-based RPPs, although they still need to be improved through trainings, while 1 other teacher does not yet have good competence, (3) Factors influencing pedagogical competence of PAI teachers in SMA Negeri 1 Sigli in preparing HOTS-based RPP consist of internal and external factors, each of which is differentiated into supporting and inhibiting factors. Supporting internal factors are self-motivation, while internal inhibiting factors are: (1) age, health and years of service and (2) ability to use media and IT-based tools. Supporting external factors are: (1) motivation and appreciation from the school; (2) participation in the district MGMP PAI forum, and (3) training, while the external factors inhibiting are: (1) limited infrastructure; and (2) the condition of students who tend to be passive.
The Ethnographic Department of the Russian Museum in the Realities of Social-Political life in the 1920s and 1930s
Authors:   Russian Museum of Ethnography, Ivanoskaya Natalia I.
Published: April 2021

The article is devoted to the one of the most important problems in the history of museum studies, namely the state museum policy. Museums participate in the historical and cultural process, relying not only on the concepts and the objectives of academic disciplines, but on the public needs of a particular historical era and the influence of power structures as well. The purpose of the study is to analyze the influence of state ideological attitudes on the research works in the field of museum ethnography and on personal fates of employees of the Russian Museum Ethnographic Department in the 1920s and 1930s, using archival sources. The author introduces into scientific circulation previously classified directive documents which regulated museum activities during that period. Considerable attention is paid to the study of the museum employees’ field reports which give an indication of the shift in the methodological approach to ethnographic studies at the time. The paper involves personal archival documents which shed a light on the details of everyday life and lifestyle, the nature of relationships between people, determined by the political organization of society, among other things.The study leads to the conclusion that the powerful ideological pressure of the state that took place during those years negatively influenced not only ethnography and museology disciplines turning them into an instrument of socialist propaganda for a certain period of time, but led many ethnographers to tragic fate.
Dos Fios que Desafiam Significados no Mundo: Notas Antropológicas Sobre Poéticas e Políticas de Morte e de Vida
Authors: Tempesta Giovana Acacia
Published: April 2021

A obra da artista visual Rosana Paulino tematiza de modo original as conexões entre cultura visual e preconceito de raça e gênero no Brasil contemporâneo. Partindo dos conceitos de biopolítica e necropolítica, formulados por filósofos e historiadores de outros continentes, encontramos o conceito de bio-necropolítica à brasileira (LIMA, 2018), que nos ajuda a refletir sobre os impactos de longa duração de práticas, ideias e estereótipos forjados durante o período escravocrata. Todavia, a antropologia nos permite compreender que a perdurabilidade de dispositivos racistas e misóginos é incapaz de encobrir completamente projetos de resistência, luta e transformação da realidade, tomados como expressões de estilos singulares de criatividade-invenção (WAGNER, 2012). Ao colocarmos em relação algumas obras de Rosana Paulino e certas ideias formuladas pela intelectual e ativista negra Lélia Gonzalez, percebemos que o alcance do trabalho da artista extrapola o mundo das artes e interessa também a uma antropologia que se indaga sobre os meandros das relações de poder.