bluuebunny/crossref_metadata_2025 huggingface dataset:
Rosnę w teatrze – edukacja i wychowanie przez teatr jako alternatywa edukacyjna
Authors: Sanecka Anna
Published: July 2023

The analysis of theatre’s impact on children’s development usually takes into account four areas: social, emotional, cognitive and cultural. Group outings to theatre are usually an entertaining and pleasant way of spending time outside of school. The article shows, on the example of selected theatre performances dedicated to children aged 4–9 years, how theatre can become an alternative to school and what theatre can teach the youngest audience in the cognitive area. The content of the watched and experienced performances is likely to remain in the minds of the audience, while they quickly forget what they have learnt at school.
Koncepcje edukacji w dyskursie posthumanistycznym
Authors: Kamińska Małgorzata
Published: July 2023

In the post-humanistic discourse, the concepts of humanity, subjectivity, civilization and knowledge change (expand) their meaning. The scale of development of digital technologies, algorithmization and automation of people’s lives also plays a significant role. Today we know that the Anthropocene epoch brought (and continues to bring) more harm than benefit in the relations between man and nature, man and man, subject and object. In addition, the pandemic crisis has sharpened the picture of problems and challenges that humanity should face. Following this, the concepts of traditional education are also being revised. The text attempts to identify educational concepts that in the near future may change the humanistic visions of education and upbringing. It is a reflection on the potential of the post-humanis- tic understanding of education in the era of civilization crisis and global threats.
Nie(równość) szans edukacyjnych zdolnych podopiecznych pieczy instytucjonalnej
Authors: Ruszkowska Marzena , Zdunkiewicz Piotr
Published: July 2023

The issue of abilities and talents is of great importance, as young people are required to possess a solid education and creativity, which talented people can certainly benefit from, especially if they are surrounded by adequate education and a supportive family environment. Unfortunately, the latter aspect is lacking in children in foster care (especially in institutional care). The researches and analyses of analyzed phenomenon allow to conclude that children in foster care are often a neglected group in terms of upbringing, education, personal models, values, and life priorities. Foster care should be an educational environment designed to compensate for deficiencies in the care, upbringing, or education of the child entrusted to it, including gifted children. Research on the educational opportunities for gifted foster care children was carried out in 6 Polish voivodeships: Lublin, Warmia-Masuria, Podlasie, Subcarpathia, Świętokrzyskie and Masovia, over a two years period – from April 2018 to June 2020. The research was quantitative and qualitative in nature. It allowed authors to conclude that a gifted child in institutional care faces numerous problems, including the lack of adequate support from both educational institutions and the foster care system in developing passions, interests, and abilities.
Don’t Stop Me Now: Cross-Border Commuting in the Aftermath of Schengen
Authors: Parenti Angela , Tealdi Cristina
Published: July 2023

A Single European Labour Market has not been achieved yet, despite strong efforts in promoting cross-country labour mobility. In this paper, we assess the effectiveness of one of the most important policies implemented to reach this goal: the Schengen Agreement. Using data from the European Labour Force Survey, we show that the individual probability to become a cross-border commuter after the entrance of Switzerland in the Schengen area increased by 0.5 and 4 percentage points among labour force individuals and inter-regional commuters, respectively. We also show evidence of a substantial redirection of internal inter-regional commuters to Swiss regions.
A Higher-Order Markov Model for a Hybrid Inventory System with Probabilistic Remanufacturing Demand
Authors: Dhaiban Ali Khaleel
Published: July 2023

This study develops a higher-order Markov model (HOM) for an inventory system with remanufacturing, substitution, and lost sales. Defective and disposed items are other factors that are considered in addition to probabilistic demand for both manufacturing and remanufacturing items. One year is the warranty period for items manufactured, and items sold return from customers to the manufacturer in increasing cumulative percentages over the months of the year. To the best our knowledge, a higher-order Markov model has rarely been used in a hybrid inventory system. The challenge is how to determine the steady state of the system with the probable demand for manufacturing and remanufacturing. We propose a new search algorithm to select the best control strategy from several strategies, and then compare it with the two-phase local search algorithm. Each state deals with (12) a probabilistic demand (policy), so the system steady state is set to (22632) policies in total for each production plan. The results showed profit maximization using the new search algorithm compared with the two-phase local search algorithm. Also, an increase in defective and returned items over time, and therefore an increase in remanufactured items. But it does not satisfy all the demand, so manufacturing increases over time due to substitution. Substitution strategy leads to increase the expected average profit.
Does Malapportionment Favor the Republican Party?
Authors: Tamas Bernard
Published: July 2023

This paper examines electoral bias within US politics, including as it relates to malapportionment in the US Senate and Electoral College. Specifically, with the Republican Party gaining significant support in rural areas and the Democratic Party becoming concentrated in urban areas, there is concern that the US electoral system increases the probability that the Republican Party will win a much higher percent of Senate seats than its public support and repeatedly win the presidency without having won a plurality of votes, as was the case in 2000 and 2016. I explore this concern using a relatively new measure called the Directional Proportionality Index (DPIx). Applying it to the Electoral College since 1872 and the US Senate since 1918, this paper demonstrates that while there does exist a small pro-Republican bias in the Electoral College owing to malapportionment, the pro-Republican malapportionment bias in Senate races is far more substantial. However, as long as the percent vote for Democratic and Republican presidential candidates remains close due to partisan polarization, this small bias in the Electoral College is likely enough to lead to more cases whereby the Republican Party loses the popular vote but still wins control over the White House and the United States Congress.
On two extensions of the annihilating-ideal graph of commutative rings
Authors: Nazim Mohd , Rehman Nadeem ur , Nisar Junaid
Published: July 2023

Let R be a commutative ring with

A
⁢

(
R
)

{A(R)}

its set of annihilating-ideals. The extended annihilating-ideal graph of R, denoted by

AG
¯

⁢

(
R
)

{\overline{\mathrm{AG}}(R)}

, is an undirected graph with vertex set

A
⁢

(
R
)

*

=

A
⁢

(
R
)

∖

{
0
}

{A(R)^{*}=A(R)\setminus\{0\}}

and two vertices

I
1

{I_{1}}

and

I
2

{I_{2}}

are adjacent if and only if

I
1
m

⁢

I
2
n

=
0

{I_{1}^{m}I_{2}^{n}=0}

with

I
1
m

≠
0

{I_{1}^{m}\neq 0}

and

I
2
n

≠
0

{I_{2}^{n}\neq 0}

, for some positive integers m and n. In this paper, we first study some basic properties of

AG
¯

⁢

(
R
)

{\overline{\mathrm{AG}}(R)}

and then we investigate the relationship between the extended annihilating-ideal graph

AG
¯

⁢

(
R
)

{\overline{\mathrm{AG}}(R)}

, the annihilator-ideal graph

A
I

⁢

(
R
)

{A_{I}(R)}

and the annihilating-ideal graph

AG
⁢

(
R
)

{\mathrm{AG}(R)}

of a commutative ring R.
Boundary contact problems with regard to friction of couple-stress viscoelasticity for inhomogeneous anisotropic bodies (quasi-static cases)
Authors: Gachechiladze Roland , Gachechiladze Avtandil
Published: July 2023

In this paper, quasi-statical boundary contact problems of couple-stress
viscoelasticity for inhomogeneous anisotropic bodies with regard to friction are investigated.
We prove the uniqueness theorem of weak solutions
using the corresponding Green’s formulas and positive definiteness of the potential energy.
To analyze the existence of solutions, we equivalently reduce the problem
under consideration to a spatial variational inequality.
We consider a special parameter-dependent regularization of this variational inequality
which is equivalent to the relevant regularized variational equation
depending on a real parameter, and study its solvability by the Galerkin approximate method.
Some a priori estimates for solutions of the regularized variational
equation are established and with the help of an appropriate
limiting procedure, the existence theorem for the original
contact problem with friction is proved.
Maps preserving the bi-skew Jordan product on factor von Neumann algebras
Authors: Darvish Vahid , Razeghi Mehran , Nouri Mojtaba
Published: July 2023

Let

𝒜

{\mathcal{A}}

and

ℬ

{\mathcal{B}}

be two von Neumann algebras. In this paper, we show that a bijective unital map

Φ
:

𝒜
→
ℬ

{\Phi:\mathcal{A}\to\mathcal{B}}

which preserves the bi-skew Jordan product is an additive

∗

{\ast}

-isomorphism. Moreover, we show that Φ is a linear

∗

{\ast}

-isomorphism or a conjugate linear

∗

{\ast}

-isomorphism.
Generating sets of F/R' Leibniz algebras
Authors: Özkurt Zeynep
Published: July 2023

Let F be a free Leibniz algebra generated by the set

X
=

{

x
1

,
…
,

x
n

}

{X=\{x_{1},\dots,x_{n}\}}

over the field K of characteristic 0 and let R be an
ideal of F. In this study, a necessary and sufficient condition for n elements of the Leibniz algebra

F
/

R
′

{F/R^{\prime}}

to be a generating set is given.
Approximate solution of the optimal control problem for non-linear differential inclusion on the semi-axes
Authors: Kasimova Nina , Zhuk Tetiana , Tsyganivska Iryna
Published: July 2023

We consider the optimal control problem of a non-linear system of differential inclusions with fast-oscillating parameters on semi-axes. Using the averaging method, we find an approximate solution for the optimal control of non-linear differential inclusions with fast-oscillating coefficients on a semi-axes.
Thus, we prove the convergence of the optimal controls of the initial control problem to the optimal process of the averaged problem and the convergence of the corresponding cost functionals.
SOEP-LEE2: Linking Surveys on Employees to Employers in Germany
Authors: Matiaske Wenzel , Schmidt Torben Dall , Halbmeier Christoph , Maas Martina , Holtmann Doris , Schröder Carsten , Böhm Tamara , Liebig Stefan , Kritikos Alexander S.
Published: July 2023

This article presents the new linked employee-employer study of the Socio-Economic Panel (SOEP-LEE2), which offers new research opportunities for various academic fields. In particular, the study contains two waves of an employer survey for persons in dependent work that is also linkable to the SOEP, a large representative German annual household panel (SOEP-LEE2-Core). Moreover, SOEP-LEE2 includes two waves of self-employed surveys based on self-employed in the SOEP-Core (SOEP-LEE2-Self-employed) and three additional representative employer surveys, independent of the SOEP in terms of sampling employers (SOEP-LEE2-Compare). Survey topics include digitalisation and cybersecurity, human capital formation, COVID-19, and human resource management. Here, we describe the content, survey design, and comparability of the different datasets in the SOEP-LEE2 to potential users in different disciplines of research.
Effect of MIMO scheme on MWIR FSO link & comparison with SWIR wavelength in the presence of different visibility and strong turbulence circumstances
Authors: Mukherjee Shibabrata , Paul Sujoy , Mazumdar Saswati
Published: July 2023

In this article, the authors analyse the performance of the “multiple input multiple output (MIMO)” technique on a free space optical (FSO) communication link using the mid wavelength infrared (MWIR) and commonly used short wavelength infrared (SWIR) in the presence of various visibility conditions like clear weather, light haze, dense haze, fog, etc., and strong turbulence regime. A 5 km link range has been considered with different diversity MIMO schemes. The performance analysis has been made for both wavelengths in terms of bit error rate (BER) and link outage probability. As the MIMO diversity is increased, the performance has been improved compared to the single input single output (SISO) scheme. In the presence of foggy conditions and higher turbulence strength, the MWIR wavelength works properly, whereas the SWIR wavelength has not worked for the same signal to noise (SNR) ratio and the same link distance.
Analysis of throughput and error rate of 16-QAM, 64-QAM, and 256-QAM O-NOMA waveforms
Authors: Kumar Arun , Gour Nidhi , Sharma Himanshu
Published: July 2023

This study presents a comprehensive analysis of the throughput performance, spectrum efficiency, and block error rate (BLER) of optical non-orthogonal multiple access (O-NOMA) waveforms using 16-quadrature amplitude modulation (QAM), 64-QAM, and 256-QAM modulation schemes. The aim is to assess the trade-offs between data rate, spectral efficiency, and error performance in O-NOMA systems. The analysis reveals that higher-order modulations, such as 64-QAM and 256-QAM, offer higher data rates and improved spectrum efficiency compared to 16-QAM. Furthermore, the study investigates the spectrum performance of the O-NOMA waveforms. The results indicate that higher-order modulations may utilise the spectrum more efficiently, maximising the data throughput within the available bandwidth. Moreover, the BLER analysis provides insights into the error performance of the O-NOMA waveforms. It quantifies the probability of errors occurring in a block of transmitted data and evaluates the system’s reliability. The analysis reveals that 256-QAM O-NOMA achieves lower BLER and high throughput in uplink and downlink as compared with the 16 and 64-QAM O-NOMA frameworks.
The effect of 50 GR oral glucose tolerance test on fetal celiac artery and superior mesenteric artery Doppler parameters in healthy pregnancies
Authors: Orgul Gokcen , Duymus Ayse Ceren , Altekin Yasin , Yanar Ahmet , Bozbay Nizamettin , Celik Cetin
Published: July 2023

Objectives

To understand the effect of 50-g oral glucose tolerance test (OGTT) on fetal celiac artery and superior mesenteric artery (SMA) Doppler parameters.

Methods

A total of 43 healthy pregnant women followed in our hospital were included in the study. All Doppler parameters of the celiac artery and SMA (peak systolic velocity (PSV); pulsatility index (PI); resistance index (RI); systolic/diastolic ratio (SD); time average maximum velocity (TAMAX)) were obtained by ultrasonography before and 1 h after OGTT.

Results

The mean PSV value of the celiac artery decreased statistically significantly after OGTT (37.29 ± 11.96 cm/s; 29.51 ± 10.07 cm/s; p=0.002). While the mean of the PI was 2.09 ± 0.57 before the test, it was found to be 1.84 ± 0.64 after the test (p=0.027). Mean PSV (39.82 ± 13.07 cm/s; 35.19 ± 15.27 cm/s; p=0.104) and PI (2.21 ± 0.65; 2.11 ± 0.80; p=0.375) values of SMA were also found to be decreased without statistically significancy.

Conclusions

The data obtained from our study reveals that the PSV and PI values of celiac artery and SMA slightly decrease after OGTT.
The Offensiveness Torts
Authors: Abraham Kenneth S. , White G. Edward
Published: July 2023

Three established torts require the defendant’s behavior to be “offensive” or “highly offensive” in order to be actionable: offensive battery, public disclosure of true private facts, and intrusion on seclusion. Although what links these “offensiveness” torts together has not been recognized before, this Article demonstrates that they occupy a sub-category of tort liability that is coherent, insight-generating, and useful. The torts developed at different times and in a sense for different reasons, but all three rest on the same principle: the idea that individual autonomy involves not only inviolable bodily space, but also inviolable private and informational space. What counts as actionable wrongdoing for these torts depends on the cultural context, because what is considered offensive conduct may vary, as cultural conditions change. The typical victim (or observer) of one of these torts must plausibly have the reaction “How dare you?” for the offensiveness element of the tort to be satisfied. That is what links these three superficially disparate torts together, and warrants understanding them together, as protections against invasions of the different forms of inviolable space that are a core feature of every individual’s autonomy.
Novel metaphor and embodiment: comprehending novel synesthetic metaphors
Authors: Zhong Yin , Ahrens Kathleen , Huang Chu-Ren
Published: July 2023

Linguistic synesthesia links two concepts from two distinct sensory domains and creates conceptual conflicts at the level of embodied cognition. Previous studies focused on constraints on the directionality of synesthetic mapping as a way to establish the conceptual hierarchy among the five senses (i.e., vision, hearing, taste, smell, and touch). This study goes beyond examining the directionality of conventionalized synesthetic terms by adopting a Conceptual Metaphor Theory approach (i.e., the Conceptual Mapping Model) to test if conventional synesthetic directionality still holds when it comes to novel metaphorical expressions. The subjects, 308 native English speakers, are asked to judge the degree of commonness, appropriateness, understandability, and figurativeness in order to measure the degree of comprehensibility of novel synesthetic metaphors. Our findings demonstrate that novel synesthetic metaphors that follow conventional directionality are considered more common, more appropriate, and easier to comprehend than those that violate conventional mapping principles; they are also judged as more literal than those that do not follow conventional directionality. This study explores linguistic synesthesia from the perspective of comprehension of novel synesthetic metaphors, posits a pivotal position for mapping principles in synesthetic directionality, and supports an embodied account of linguistic synesthesia.
A Compass for What Matters: Applying Virtue Ethics to Information Behavior
Authors: Gorichanaz Tim
Published: July 2023

Out of the three major approaches to ethics, virtue ethics is uniquely well suited as a moral guide in the digital age, given the pace of sociotechnical change and the complexity of society. Virtue ethics focuses on the traits, situations and actions of moral agents, rather than on rules (as in deontology) or outcomes (consequentialism). Even as interest in ethics has grown within information behavior (IB), there has been little engagement with virtue ethics. To address this lacuna and demonstrate further research opportunities, this article provides an overview of virtue ethics for application in IB (broadly defined). It provides a primer on virtue ethics, gives examples of existing IB work that is compatible with virtue ethics, and suggests avenues for further virtue-oriented research in IB.
Chaotic characteristics and mixing performance of pseudoplastic fluids in a stirred tank
Authors: Zhang Xiang , Si Wen , Zhao Chengzhi , Luan Deyu
Published: July 2023

The key for improving the mixing efficiency of pseudoplastic fluids is to enhance the chaotic degree in the flow field. The xanthan gum solution was used to study the chaotic characteristics and mixing performance in a stirred tank with the impeller of perturbed six-bent-bladed turbine. Based on the velocity time series collected by the experiment of particle image velocimetry (PIV), the distributions of the largest Lyapunov exponent (LLE) and Kolmogorov entropy (K entropy) of the system were obtained through the programming calculation using the software MATLAB (R2016a) for characterizing the chaotic degree. The mixing performance of the fluid was numerically investigated using the Computational Fluid Dynamics package, and the velocity distributions were compared with the results obtained by the experiment of PIV. The relevance between the chaotic degree and the mixing performance was clarified. Results showed that the numerical results of velocity distributions agreed well with the experimental data which validated the Computational Fluid Dynamics model established. When the speed reached 600 rpm, the LLE and K entropy climbed the maximal values at the same time, which meant the greatest degree of chaos, and the mixing energy per unit volume was minimal at that moment, which was corresponding to the highest mixing efficiency. As the speed increased further, the LLE and K entropy decreased instead, which meant the chaos reduction, and the corresponding mixing energy per unit volume increased with the low mixing efficiency.
Recent developments in the mechanical properties of hybrid fiber metal laminates in the automotive industry: A review
Authors: Xiao Hanyue , Sultan Mohamed Thariq Hameed , Shahar Farah Syazwani , Gaff Milan , Hui David
Published: July 2023

In the face of fierce competition in the automotive market, severe environmental problems, and the consistent enhancement of consumer demands for vehicle performance, research and development for new automotive materials have increased. Fiber metal laminate (FML) is a representative hybrid composite in recent years but the application of FMLs in the automotive industry is still rare. In order to boost the strengths and applications of FMLs, a lot of effort has been put into enhancing their mechanical properties. In this review article, up-to-date information on the mechanical performance of FMLs for automotive components is presented. The mechanical testing methods, materials selection, structure design, fabrication methods, and the application of hybrid FMLs were explored. The objective of this review article is to study different factors that influence the mechanical properties of FMLs and provide some optimization directions from various aspects. From recent research, there will be great opportunities for hybrid FMLs utilizing natural fibers and bio-polymers in the automotive field in the future.
Preparation and application of foamed ceramic panels in interior design
Authors: Wang Bin
Published: July 2023

A new type of foam ceramics was prepared with fly ash (CFA). Before sintering, the CFA underwent alkali activation, resulting in an even layer of hydroxy sodalite crystals covering the CFA particles. The pre-treatment of the CFA-alkali-activated material caused it to exhibit a reaction in sintering. The foamed ceramics had the best qualities when sintered at 1,300°C; the leaching toxicity studies of a material used in interior design revealed that during sintering.
Újabb problémafelvetések az Istenes énekek kiadástörténetéhez
Authors: Horváth Margaréta
Published: July 2023

Dolgozatom a Balassi Bálint és Rimay János vallásos líráját közreadó, a 17–18. században sokszor megjelenő versgyűjtemény, az Istenes énekek kiadástörténetét tárgyalja. Az első ilyen kiadványok általában két részből tevődnek össze: a Balassi neve alatt közölt, de valójában mindkét szerző műveit felölelő törzsanyagból, és egy vegyes énekrészből. Ezeket az edíciókat nevezi a szakirodalom összevegyítő vagy másképp rendezetlen kiadásoknak. Téziseim a következők. 1) Az a tény, hogy a néhány levélnyi töredékben ránk maradt editio princeps vegyes része a „Balassa Bálintnak istenes éneki” fejléccel jelent meg, arra utal, hogy az őskiadásban a versanyag még kevéssé volt elválasztva Balassitól. 2) Az 1665-ös kassai kiadásban fennmaradt előszóról tévesen gondolják a szakírók, hogy az eredetileg az őskiadás élén állhatott. 3) Vonatkozó tanulmányában Vadai István szándéka ellenére nem az editio princeps tartalomjegyzékét rekonstruálja, hanem egy számunkra ismeretlen kiadásét.
Preliminary Use of Convection-allowing Models in Fire Weather
Authors: Lindley T. Todd , Zwink Alexander B. , Barnes Ryan R. , Murdoch Gregory P. , Ancell Brian C. , Burke Patrick C. , Skinner Patrick S.
Published: July 2023

Multiple high-impact wildfire episodes on the southern Great Plains in 2021/22 provided unique opportunities to demonstrate the emerging utility of Convection-allowing Models (CAMs) in fire-weather forecasting. This short contribution article will present preliminary analyses of the deterministic Texas Tech Real Time Weather Prediction System’s Red Flag Threat Index (RFTI) compared to wildfire activity observed via the Geostationary Operational Environmental Satellite-16 during four southern Great Plains wildfire outbreaks. Visual side-by-side comparisons of model-predicted RFTI and satellite-detected wildfires will be shown in static and animated displays that demonstrate the model’s prognostic signal in depicting fire-outbreak evolution. The data analyses are supplemented with preliminary information from state forestry agencies that provide context to predicted RFTI relative to size-based categorization of observed wildfires and human casualties. In addition, use of the National Severe Storm Laboratory’s Warn-on-Forecast System to provide short-term updates on the evolution of fire-effective atmospheric features that promote new fire ignition, problematic spread, and extreme fire behavior is also demonstrated. The examples presented here suggest that CAMs serve an important role in the mesoscale prediction of dangerous wildfire conditions. With this novel use of CAMs in fire meteorology, the authors advocate for expanded availability of fire weather-specific fields and parameters in high-resolution numerical weather prediction systems that would improve wildfire forecasts and associated impact-based decision support.
Conhecimento teórico-prático da equipe de enfermagem referente à reanimação cardiopulmonar no âmbito intra-hospitalar / Theoretical-practical knowledge of the nursing team regarding cardiopulmonary resuscitation in the hospital environment
Authors: Oliveira Thaísa Mariela Nascimento , Lima Priscila Alvim , Scholze Alessandro Rolim
Published: July 2023

Objetivo: descrever o conhecimento teórico-prático da equipe de enfermagem referente a reanimação cardiopulmonar no âmbito intra-hospitalar. Método: revisão integrativa, realizada em Literatura Latino-Americana e do Caribe em Ciências da Saúde, Medical Literature Analysis and Retrieval System Online e Base de Dados em Enfermagem. Foram incluídos artigos originais, disponíveis na íntegra, publicados de 2010 a 2020, em qualquer idioma Resultados: como potencialidade, os profissionais sabem como detectar os sinais de parada cardiorrespiratória e realizar a sequência da reanimação cardiopulmonar do suporte básico de vida. Já como fragilidades, a maioria dos profissionais não sabe como realizar a relação compressão/ventilação do suporte avançado de vida, nem como identificar ritmos cardíacos ou fármacos utilizados. Conclusão: o conhecimento da equipe de enfermagem, referente a temática, encontra-se fragilizado e está relacionado à importância das capacitações nas instituições de saúde.
Fabrication and in vitro evaluation of polyvinyl alcohol/bio-glass composite for potential wound healing applications
Authors:   Department of Biomedical Engineering, NED University of Engineering and Technology, Karachi, Pakistan, Khan T. , Mirza E. H. ,   Department of Biomedical Engineering, NED University of Engineering and Technology, Karachi, Pakistan, Kurd N. J. ,   Department of Biomedical Engineering, NED University of Engineering and Technology, Karachi, Pakistan, Naushad M. ,   Department of Biomedical Engineering, NED University of Engineering and Technology, Karachi, Pakistan, Ul Haque M. Z. ,   Department of Biomedical Engineering, Salim Habib University, Karachi, Pakistan
Published: July 2023

In this study, a novel composite is fabricated by incorporating Polyvinyl alcohol (PVA) and Bio-Glass (BG) via the freeze-thaw method. PVA pre-polymer is prepared in three different concentrations i.e. (2%, 5%, and 10%) by dissolving PVA powder in distilled water by using a hot plate magnetic stirrer at 80° C, and a constant concentration of BG i.e 2% is added into each PVA prepolymer. Total six specimens including (PVA (2%), PVA (5%), PVA (10%), PVA (2%)/BG (2%), PVA (5%)/BG (2%), and PVA (10%)/ BG (2%) were prepared in which pure PVA specimens acts as a control group. The physicochemical and mechanical properties of the specimens were examined. Various characterization tests such as scanning electron microscopy (SEM), swelling analysis, degradability analysis, hygroscopicity, pH sensitivity, tensile analysis, gel fraction test, water vapor transmission rate (WVTR), and, contact angle analysis were performed on the samples. SEM analysis showed that with the increase in PVA concentration, the material becomes smoother and more compact. Results from the current study showed that tensile strength, degradation rate, and get content are directly proportional to PVA concentration, while swelling capacity, pH sensitivity, hygroscopicity, WVTR, and hydrophilicity are inversely related to PVA concentration. Moreover, with the addition of BG, tensile strength, degradation rate, pH sensitivity, swelling capability, hydrophilicity, and, gel content of the specimens is increased, whereas, WVTR is decreased and, hygroscopicity remains unchanged. Furthermore, results from this study must be taken a step ahead & biocompatibility must be tested to evaluate the biological performance.
Actionable loss of SLF2 drives B‐cell lymphomagenesis and impairs the DNA damage response
Authors: Zhang Le , Wirth Matthias , Patra Upayan , Stroh Jacob , Isaakidis Konstandina , Rieger Leonie , Kossatz Susanne , Milanovic Maja , Zang Chuanbing , Demel Uta , Keiten‐Schmitz Jan , Wagner Kristina , Steiger Katja , Rad Roland , Bassermann Florian , Müller Stefan , Keller Ulrich , Schick Markus
Published: July 2023

The DNA damage response (DDR) acts as a barrier to malignant transformation and is often impaired during tumorigenesis. Exploiting the impaired DDR can be a promising therapeutic strategy; however, the mechanisms of inactivation and corresponding biomarkers are incompletely understood. Starting from an unbiased screening approach, we identified the SMC5‐SMC6 Complex Localization Factor 2 (SLF2) as a regulator of the DDR and biomarker for a B‐cell lymphoma (BCL) patient subgroup with an adverse prognosis. SLF2‐deficiency leads to loss of DDR factors including Claspin (CLSPN) and consequently impairs CHK1 activation. In line with this mechanism, genetic deletion of Slf2 drives lymphomagenesis in vivo. Tumor cells lacking SLF2 are characterized by a high level of DNA damage, which leads to alterations of the post‐translational SUMOylation pathway as a safeguard. The resulting co‐dependency confers synthetic lethality to a clinically applicable SUMOylation inhibitor (SUMOi), and inhibitors of the DDR pathway act highly synergistic with SUMOi. Together, our results identify SLF2 as a DDR regulator and reveal co‐targeting of the DDR and SUMOylation as a promising strategy for treating aggressive lymphoma.
Genetic effects on molecular network states explain complex traits
Authors: Weith Matthias , Großbach Jan , Clement‐Ziza Mathieu , Gillet Ludovic , Rodríguez‐López María , Marguerat Samuel , Workman Christopher T , Picotti Paola , Bähler Jürg , Aebersold Ruedi , Beyer Andreas
Published: July 2023

The complexity of many cellular and organismal traits results from the integration of genetic and environmental factors via molecular networks. Network structure and effect propagation are best understood at the level of functional modules, but so far, no concept has been established to include the global network state. Here, we show when and how genetic perturbations lead to molecular changes that are confined to small parts of a network versus when they lead to modulation of network states. Integrating multi‐omics profiling of genetically heterogeneous budding and fission yeast strains with an array of cellular traits identified a central state transition of the yeast molecular network that is related to PKA and TOR (PT) signaling. Genetic variants affecting this PT state globally shifted the molecular network along a single‐dimensional axis, thereby modulating processes including energy and amino acid metabolism, transcription, translation, cell cycle control, and cellular stress response. We propose that genetic effects can propagate through large parts of molecular networks because of the functional requirement to centrally coordinate the activity of fundamental cellular processes.
Entrepreneurial Intentions: Between Entrepreneurial Knowledge, Entrepreneurial Skills and Perceived Control Behavior
Authors: Kurjono Kurjono
Published: July 2023

This study aims to analyze the effect of entrepreneurial knowledge, entrepreneurial skills, and planned control behavior on entrepreneurial intentions. The grand theory used is Teri Planned Behavior from Ajzen (1991). The explanatory survey method was employed as the research method of the study. The research population comprised 506 students with a sample size of 218 respondents. The research sample was taken from a population of all Indonesian accounting education students consisting of students who had attended entrepreneurship courses from the Universitas Pendidikan Indonesian (UPI), Universitas Negeri Yogyakarta Negeri (UNY), Universitas Sebelas Maret (UNS), Universitas Negeri Surabaya (UNESA), Universitas Negeri Malang (UM), Universitas Negeri Makasar (UNM) and Universitas Negeri Medan (UNIMED). As the strategy to collect data, all questionnaires in this study have been tested for validity and reliability. Data were analyzed through descriptive analysis and path analysis. The results indicate that entrepreneurial knowledge did not affect perceived control behavior. Thus, variable trimming is conducted. Entrepreneurial skills have a positive effect on perceived control behavior. Similarly, entrepreneurial skills impact entrepreneurial intentions. Perceived behavior control has a positive effect on entrepreneurial intentions. Perceived behavior control is the most dominant variable in influencing entrepreneurial intentions. Future research is recommended to increase entrepreneurship from indicators of experience such as knowing client's problems and entrepreneurial skills, for example, indicators of recognizing opportunities, perceived behavior control through indicators of having opportunities for success, and entrepreneurial intentions through the business ability to start a business.
Can Interest in Using Paylater Mediate Impulse Buying Behavior Online?
Authors: Mahmud Amir , Fatikhah Nuril
Published: July 2023

This study aimed to analyze the effect of price rationality, sales promotion, and hedonic lifestyle on impulsive buying behaviour with an interest using paylater as a mediating variable. The research population is active students of the Faculty of Economics, Universitas Negeri Semarang class of 2019, totaling 974 students. The sampling technique used simple random sampling amounted to 284 students. Methods of data collection used a questionnaire and used descriptive analysis techniques and path analysis techniques with the Structural Equation Model by SmartPLS 3.0. The results of this study showed that all variables had a positive and significant effect on online impulsive buying behaviour. Interest using paylater is able to partial mediation the influence of price rationality, sales promotion, and hedonic lifestyle on online impulsive buying behaviour. Based on the conclusion above, researchers provide suggestions in the form of support so that in the future students are able to manage finances wisely, students continue to deepen their knowlegde of finance so students can sort out product that are really in a sales promotion in the sense that they are not tempted by marketing so they can adjust their needs.
Legal Aid in Sexual Violence Cases (Novia Widyasari Case)
Authors: Pamungkas Bambang , Fitriana Debby , Fitriyana Devita Nur , Azizah Ranti Nur , Rajagukguk Anita Carolina
Published: July 2023

The provision of legal assistance for cases of sexual violence against women, especially in the case of Novia Widyasari, still has many obstacles and challenges in its implementation. The challenge lies in 3 (three) legal systems, namely legal culture, legal substance, and legal structure. Of the three forms of challenge, the most dominating is the third challenge, namely the legal structure, namely the quality of law enforcement. With the provision of legal assistance in the form of advocacy services based on assistance and exclusive defense of victims' rights, it is hoped that it can be a stimulus in the process of upholding justice for victims of sexual violence.
Preventing Religious Radicalism in Indonesian Society (Case of Gunungpati Subdistrict, Semarang City)
Authors: Masyhar Ali , Pawenang Eram Tunggul , Wahyudi Wahyudi , Justicea Nadela , Lagura Syatriawan , Setiawati Juniza Indah
Published: July 2023

Terror acts always begin with the cultivation of radicalism. For this reason, it is necessary to take preventive measures to block the spread of these radicalisms. One form of radicalism that needs to be watched out for is social radicalism. Religious radicalism has recently shown an increase. This activity aims to foster a preventive attitude in order to counteract the streams of radicalism in the people of the Gunungpati District of Semarang City against the streams of terrorism and radicalism and provide input to the government regarding the forms of action that must be taken in order to provide legal protection for the people of the Gunungpati District of Semarang City against religious sects. -terrorism and radicalism. This activity is in partnership with the Ats-Tsaqofah Semarang Foundation as a community empowerment institution, especially in the development of religious morals for community members. The method used in the activity is the lecture and dialogue method, as well as focused discussion. In addition, the brainstorming method from the audience will also be used, as an effort to extract their initial knowledge about terrorism and radicalism. From this activity, it is hoped that preventive attitudes will grow to counteract the streams of radicalism that enter society.
Victims of Robbery with the Forced Defence (Noodweer): A Legal and Victimological Aspects
Authors: Rizkyta Amelia Putri , Holish Amarru Muftie
Published: July 2023

This study aims to analyze criminal arrangements in the case of victims of violent crimes who then defended forced to exceed the limit due to coercion. This research is normative legal research through a conceptual approach. The results of this study show that victims of violent crimes who commit criminal acts as a defense effort are forced to be free from crime if they meet the requirements based on Articles 48-51 of the Criminal Code. Article 5 Paragraph (1) of Law Number 13 of 2006 concerning the Protection of Witnesses and Victims also explains that victims have the right to protection and a sense of security if there is a gross violation of human rights. However, to get this right, victims still have to go through the legal process.
Total thyroidectomy: reduction in postoperative hypoparathyroidism
Authors: Reinke Rasmus , Londero Stefano Christian , Almquist Martin , Rejnmark Lars , Rolighed Lars
Published: July 2023

Objective

Total thyroidectomy is associated with a high risk of postoperative hypoparathyroidism, mainly due to the unintended surgical damage to the parathyroid glands or their blood supply. It is possible that surgeons who also perform parathyroid surgery see lower rates of postoperative hypoparathyroidism. In a single institution, we investigated the effects of restricting total thyroidectomy operations for Graves’ disease to two surgeons who performed both thyroid and parathyroid surgeries. We aimed to evaluate the rates of postoperative hypoparathyroidism in a 10-year period with primary attention toward patients with Graves’ disease.

Design

Retrospective cohort study from a single institution.

Methods

We defined the rate of permanent hypoparathyroidism after total thyroidectomy as the need for active vitamin D 6 months postoperatively. Between 2012 and 2016, seven surgeons performed all thyroidectomies. From January 2017, only surgeons also performing parathyroid surgery carried out thyroidectomies for Graves’ disease.

Results

We performed total thyroidectomy in 543 patients. The rate of permanent hypoparathyroidism decreased from 28% in 2012–2014 to 6% in 2020–2021. For patients with Graves’ disease, the rate of permanent hypoparathyroidism decreased from 36% (13 out of 36) in 2015–2016 to 2% (1 out of 56) in 2020–2021. In cancer patients, the rate of permanent hypoparathyroidism decreased from 30% (14 out of 46) in 2012–2014 to 10% (10 out of 51) in 2020–2021.

Conclusion

Restricting thyroidectomy to surgeons who also performed parathyroid operations reduced postoperative hypoparathyroidism markedly. Accordingly, we recommend centralisation of the most difficult thyroid operations to centres and surgeons with extensive experience in parathyroid surgery.

Significance statement

Thyroid surgery is performed by many different surgeons with marked differences in outcome. Indeed, the risk of postoperative permanent hypoparathyroidism may be very high in low-volume centres. This serious condition affects the quality of life and increases long-term morbidity and the patients develop a life-long dependency of medical treatments. We encountered a high risk of hypoparathyroidism after the operation for Graves’ disease and restricted the number of surgeons to two for these operations. Further, these surgeons were experienced in both thyroid and parathyroid surgeries. We show a dramatic reduction in postoperative hypoparathyroidism after this change. Accordingly, we recommend centralisation of total thyroidectomy to surgeons with experience in both thyroid and parathyroid procedures.
Mineralocorticoid receptor signalling in primary aldosteronism
Authors: Yang Jun , Young Morag J , Cole Timothy J , Fuller Peter J
Published: July 2023

Primary aldosteronism, or Conn syndrome, is the most common endocrine cause of hypertension. It is associated with a higher risk of cardiovascular, metabolic and renal diseases, as well as a lower quality of life than for hypertension due to other causes. The multi-systemic effects of primary aldosteronism can be attributed to aldosterone-mediated activation of the mineralocorticoid receptor in a range of tissues. In this review, we explore the signalling pathways of the mineralocorticoid receptor, with a shift from the traditional focus on the regulation of renal sodium–potassium exchange to a broader understanding of its role in the modulation of tissue inflammation, fibrosis and remodelling. The appreciation of primary aldosteronism as a multi-system disease with tissue-specific pathophysiology may lead to more vigilant testing and earlier institution of targeted interventions.
Joachim Lelewel’s Collections Journey from Kórnik to Vilnius
Authors: Leonavičiūtė Inga
Published: July 2023

Vilnius University Library possesses in its collections the personal library of distinguished historian, Joachim Lelewel (1786–1861), an alumnus and a professor of the Imperial University of Vilna. It consists of books, atlases, maps and other stocks gathered by Lelewel during his exile in Paris and Brussels. In his will, Lelewel bequeathed his library to Vilnius University, should that remembrance institution be restored. The library was temporarily stored at several locations, such as the Polish School at Batignolles (Paris), and Kórnik Library after 1874. In the fall of 1919 Vilnius University was reestablished by the Polish government under the name Stefan Batory University. The institution inherited former university’s meager library which had experienced heavy losses and deprivation during the decades of the Russian rule. Bringing to Vilnius extensive assets of printed and archival records gathered by the Polish emigrants in Western Europe through the 19th century was a great opportunity for the university library as it might significantly enrich its modest possessions. Lelewel’s personal library as well as Library and Archives of the Polish Museum at Rapperswil (Switzerland) were considered as first to be transferred. This article uses archival data to reconstruct almost a four-year long (February 1922 – end of 1925) journey of the Lelewel’s library from Kórnik to Vilnius.
A Pinch of Thoughts on the Life and Work of Zenonas Ivinskis
Authors: Stanevičius Ignas
Published: July 2023

-
Wild food plants with the potential to improve food and nutrition security may be threatened by timber extraction: A systematic review of the Brazilian context
Authors: Caetano Roberta , Monique da Costa Santos Élida , Zago Poian Richard , Rosa Carvalho Adriana , Ricardo Vasconcelos da Silva Rafael , Muniz de Medeiros Patrícia
Published: July 2023

Wild food plants can contribute to improving the food and nutrition security of local populations by promoting diet diversification and increasing the intake of micro- and macronutrients. However, many of these plants are also used as timber. Wild food species need to be identified and their food–wood use interactions need to be well understood for the development of conservation strategies, as species with the potential to improve food and nutrition security may be threatened by destructive extraction. This systematic review recorded and compiled nutritional information on woody plant species native to Brazil that are used by local populations for food and timber purposes, seeking to identify which species have a high overlap between food and timber uses as well as a high nutritional potential. A total of 635 woody species with timber and/or food uses were identified. Of this total, at least 42 species find application in all timber use categories analyzed in this study, being considered versatile. Comparison of ethnobiological and nutritional data revealed nine versatile species for which nutritional composition information was available, among which three stood out in terms of macronutrient contents, namely Anacardium occidentale L., Bauhinia cheilantha (Bong.) Steud., and Eugenia pyriformis Cambess. Many versatile species classified as threatened or in decline have not been the focus of nutritional studies, which signals the need for greater nutritional research efforts. It is also necessary to investigate whether food importance exerts any protective effect on these species, reducing timber use pressure (protection hypothesis).