bluuebunny/crossref_metadata_2025 huggingface dataset:
Atendimento pré-natal na Atenção Primária à Saúde durante o período de pandemia da COVID-19
Authors: Marques Rakely Fernandes Araújo , Nascimento Fransuélio Félix do , Carvalho Neusa Moreira de , Queiroz Laurencia Maciel , Brito Helton Djohnson Silva , Sousa Milena Nunes Alves de
Published: August 2021

A atenção ao pré-natal abrange ações de educação em saúde, identificação de riscos, prevenção e tratamento de complicações e agravo. Esse acompanhamento acontece de forma rotineira na Atenção Primária à Saúde (APS), podendo se estender a outros níveis de assistência a partir das Redes de Atenção à Saúde (RAS) com a finalidade garantir a integralidade conforme as necessidades que a gestante porventura venha apresentar. O objetivo do trabalho foi relatar a experiência da prática do acompanhamento pré-natal na APS no período de pandemia da COVID-19. A busca ativa foi necessária para contatar essas gestantes, sendo realizada através do ACS e também de prontuários. Foram realizadas consultas compartilhadas pelos residentes multiprofissionais os quais se dividam entre categorias como enfermagem, psicologia, educação física e serviço social. Foi possível além das consultas compartilhadas, consultas uniprofissionais quando havia demanda existente para tal. A experiência proporcionou transformação de realidades do atendimento a essas mulheres e também satisfação profissional.
ANSIEDADE E O USO INDISCRIMINADO DE ANSIOLÍTICOS
Authors: Felix Franceildo Jorge , BEZERRA GOUVEIA ALICE GERÔNIMO , TEIXEIRA VIDAL JOSÉ EVALDO , ALBUQUERQUE DE OLIVEIRA CABRAL SYMARA ABRANDE , ALMEIDA CARLOS ROBERTO DA SILVA , MANGUEIRA VIVIANNE MENDES
Published: August 2021

RESUMO: A ansiedade é um problema comum e crescente na sociedade atual, tendo em vista que a humanidade está passando por elevados níveis de estresse, pressão psicológica e outros fatores, produzindo aumento pela busca de substâncias e métodos que provoquem a sensação de alívio, bem-estar físico e mental. O uso de fármacos psicoativos é eficaz em determinadas situações, porém, o abuso e a automedicação são questionados. O uso indiscriminado é uma ocorrência constante na sociedade atual, gerando preocupação nas autoridades de saúde, pois, sabe-se que a utilização prolongada destes fármacos causa efeitos colaterais indesejáveis, dependência química e dificuldades para finalizar o tratamento. Essa pesquisa tem como objetivo caracterizar a importância do farmacêutico quanto ao uso racional de ansiolíticos. Trata-se de uma revisão bibliográfica do tipo exploratória. O período de busca foi realizado entre os meses de setembro de 2019 a maio de 2020, utilizando-se as seguintes bases de dados: Biblioteca Virtual em Saúde (BVS), Literatura Latino Americana e do Caribe em Ciências da Saúde (LILACS), Scientific Eletronic Library On Line (SCIELO). Foram incluídos cinco artigos da literatura nacional que abordam sobre o uso de ansiolíticos de forma irracional e a importância do acompanhamento profissional para reduzir o consumo indiscriminado de medicamentos para ansiedade. A utilização de ansiolíticos, especialmente os benzodiazepínicos, em idosos é cada vez mais comum e está associada a alta susceptibilidade que esse grupo apresenta para transtornos mentais. Na perspectiva de reduzir o uso indiscriminado de psicotrópicas, os medicamentos que estão inseridos na classe dos ansiolíticos, devem ser discutidos no meio cientifico como práticas que contribuam para o uso racional, de modo que esses fármacos sejam prescritos com reais indicações clínicas. Foi possível evidenciar que ainda existe uma grande prevalência do uso indiscriminado de ansiolíticos no Brasil, relacionado a vários fatores como: falta de conhecimento do diagnóstico, do tratamento em si, tempo de ação da droga, efeitos e eventos adversos, cabendo aos profissionais, que lidam com medicamentos, atenção para práticas educacionais, tanto para usuários, quanto para os profissionais de saúde, incluindo o farmacêutico, uma vez que espera - se que este profissional domine todos esses aspectos e no momento da dispensação realize as devidas orientações com vistas a prevenção do uso indiscriminado.
Relação trabalho saúde dos bombeiros militares do 4º batalhão de bombeiro militar da Paraíba
Authors: Leite Elizandra da Silva Medeiros , Santos Everson Vagner de Lucena , Macedo Anuska Erika Pereira Bezerra
Published: August 2021

Objetivou-se identificar as condições de relação trabalho saúde dos bombeiros militares do 4º Batalhão de Bombeiro Militar da Paraíba, Sendo do tipo quantitativo, descritivo, transversal e de campo. A população foi constituída por 58 Bombeiros Militares Pertencentes ao 4º Batalhão de Bombeiro Militar da Paraíba. Foi utilizado dois questionários: o primeiro questionário de Avaliação de Qualidade de Vida e da Saúde (QVS-80) modificado e o segundo questionário utilizado foi o Goldberg adaptado. Os resultados mostram que os soldados do 4º Batalhão de Bombeiro Militar da Paraíba que participaram da pesquisa apresentaram jornadas longas de trabalho resultando em um efeito direto na diminuição do tempo disponível para outras atividades físicas, levantando demandas prejudiciais à saúde e favorecendo problemas no trabalhos. A sobrecarga de peso e os problemas com a ergonomia tem sido as variáveis mais apontadas no estudo como preditivo para o aparecimento de agravos a saúde dos bombeiros militares. Jornadas amplas de serviços produzem dificuldades nas relações pessoais, sociais e familiares, além disso influenciam no tempo disponível para o cuidado com a saúde, podendo assim acarretar doenças ocupacionais. Com isso, os trabalhadores acabam que reduzindo os horários para exercícios físicos que poderiam ajudar no seu desempenho e na diminuição de problemas de saúde. Este estudo recomenda ações pontuais, sobretudo na adequação do ambiente de trabalho na questão de ergonomia e exercícios voltados ao condicionamento físico, visando preservar o bem-estar desses soldados para que se conservem ativos e colaborem ainda mais com a sociedade regional, assegurando o cumprimento da missão de resguardar vidas e bens da população.
The Digital Classroom: A Digital Humanities Primer on Tools, Methods, and Resources
Authors: Moisich Oliver
Published: August 2021

This article will focus on teaching with digital humanities (DH) methods and tools as they relate to their practicability in the context of the classroom. It will concentrate on the specific challenges that the teaching of computational methods pose to educators who are experts in their discipline but might feel that they lack the technical know-how to steer their students towards DH. In particular, the article will introduce a number of tools that allow school students and educators to access digital approaches and to start appreciating their relevance for research. These include online resources for literary analysis, simple programs that may be used for research into media, and archival projects that stem from the collaboration of students and staff and bring neglected histories to an outside audience. While these tools do not demand any practical programming knowledge, I will also present resources that teach widely used coding languages such as Python and R on a step-by-step basis. The third and final part of the article will introduce a number of methods and services that empower educators to create a digital classroom with quantitative approaches and distant learning as their primary characteristics. Teaching these methods might prove challenging at first.; yet the hands-on, collaborative, quality of DH also leads to classroom situations in which students and staff become co-learners, and therefore leads to a democratizing effect.
Outcomes of the Latarjet Procedure in Recurrent Anterior Shoulder Instability due to Tramadol-Induced Seizure
Authors: Guity Mohammadreza , Najafi Arvin , Mansouri Pejman , Bagheri Nima
Published: August 2021

Background: This study was aimed to evaluate the final results of surgical treatment (Latarjet procedure) in the recurrent anterior shoulder instability following episodes of tramadol-induced seizure.
Methods: From January 2005 to March 2013, 47 patients with recurrent anterior shoulder dislocation after suffering a seizure episode following tramadol use underwent surgical procedure. There were 53 shoulders in 47 male patients (six had bilateral recurrent dislocations). The mean age of the patients at the time of operation was 24.7 years (ranging from 20 to 44 years). The average number of episodes of anterior shoulder dislocation before surgery was 16.
Results: External rotation with the elbow at the side improved from 45.8 ± 9.3° (30°-60°) pre-operatively to 61.5 ± 7.8° (45°-90°) postoperatively (P < 0.001). Forward elevation also increased significantly post-operatively (P = 0.002). Mean pre-operative Rowe score was 28.41 ± 4.30 (30-85) which increased to 73.57 ± 8.40 post-operatively. The Western Ontario Shoulder Instability Index (WOSI) score decreased from 1352 ± 74 to 618 ± 46 (P < 0.0001).
Conclusion: Correcting glenoid bone loss by Latarjet procedure combined, if necessary, with humeral head defect reconstruction could be a proper treatment method in patients experiencing recurrent anterior shoulder dislocation after idiosyncratic seizure reaction of tramadol.
Reduction Techniques in Displaced Femoral Neck Fracture: Educational Corner
Authors: Moshirifar Mohammad , Moharrami Alireza , Moazen Jamshidi Mir Mansour , Mortazavi Seyed Mohammad Javad
Published: August 2021

The article's abstract is not available.
Pediatric Proximal Radius Fracture and Reduction Techniques: An Educational Review
Authors: Taheri Hassan , Tahririan Mohammad Ali
Published: August 2021

The article's abstract is not available.
Compliance with the requirements for notifying the employer of the creation of a service invention, as a guarantee of excluding its arbitrary interpretation
Authors:   PhD (law), prosecutor of the Zarechensky district of Tula, Zenkin A.N.
Published: August 2021

This article discusses the necessary list of information that an employee must specify in the notification to the employer when creating a protable service invention.
Modern model of state anti-corruption policy in the countries of the European Union
Authors:   head of Research at the Siberian institute of management (branch) of the RANEPA, V.E. Shorokhov
Published: August 2021

This article continues a series of copyright research on the ongoing state anti-corruption policy in Russia and abroad in terms of legal framework. The analysis of the specifics of the modern model of state anti-corruption policy of the EU countries and the features of its implementation in the framework of international and national law is carried out. The necessity of perceiving positive global experience and adapting individual measures of the considered anti-corruption models in the Russian legal field is emphasized.
Criminal procedure and criminalistics aspects of obtaining information about Internet users in the course of investigative actions
Authors:   PhD (law), deputy head of the department of criminalistics of the Omsk academy of the MIA of Russia, D.M. Safronov , K.S. Sidorova ,   Lecturer of the department of criminalistics of the Omsk academy of the MIA of Russia
Published: August 2021

This article states that against the background of user interaction with the Internet resources, several groups of traces are formed: the first characterizes the formal or technical side of the user’s connection to the Internet (IP address, MAC address or IMEI, time and period connections); the second group of traces reflects the content or informational component of the connection (personal data of the user; his actions with multimedia content; reflects the interaction with subscribers: correspondence, sending information), for obtaining information about which there are significant difficulties. Therefore, it is proposed to consider the features of the production of individual investigative actions in order to extract forensically significant information from the Internet.
The problem of family (domestic) violence during the fight against a new coronavirus infection: prevention issues
Authors:   LL.D., head of the department of criminal process of the Orenburg state university, Volosova N.Y. , Zhurkina O.V. , Filippova E.O. ,   head of the department of organization of judicial and prosecutorial-investigative activities of the Orenburg state university,   candidate of pedagogical sciences, senior lecturer of the department of criminal law of the Orenburg state university
Published: August 2021

The article deals with the problem of family (domestic) violence, which worsened during the period of lockdown. The search for effective means of preventing family (domestic) violence remains an urgent issue today. The problem requires efforts not only from law enforcement agencies. Prevention measures should be comprehensive and involve the resources of both law enforcement agencies and society as a whole.
Problems of improving legislation in the field of regulation of measures of civil liability and sanctions for causing harm and losses by violations of non-contractual (tort) civil obligations
Authors:   PhD (law), senior lecturer of the department of arbitration, civil and administrative procedure of the North-Caucasus institute (branch) of the All-Russian state university of justice, Ibragimova A.I.
Published: August 2021

The article notes that without legislatively established harsh measures to counter the commission of non-contractual civil law offenses — tort, the fundamental principle of maintaining a stable civil law order and lawful civil turnover cannot be implemented, it is proposed to prevent the commission of noncontractual civil law crimes (tort) ) to make amendments, amendments and additions to certain legislative acts aimed at establishing additional civil sanctions and the actual and legal consequences arising from their application.
Administrative barriers to business: minimization in the context of the reform of state control and supervision.
Authors:   PhD (law), senior lecturer of the Penza state university, Agamagomedova S.A.
Published: August 2021

The article deals with administrative barriers for business in the context of reforming the system of state control and supervision. Developing the typology of administrative barriers, the author offers options for the correlation of the categories ‘administrative barriers in the economy’, ‘administrative barriers for business’, ‘administrative barriers in the passage of state control and supervision’. Supporting the procedural concept of administrative barriers, the author concludes that the minimization of administrative barriers for business as a vector of reform of control and supervisory activities of executive authorities. Digitalization of state control and supervision; transfer of a part of the controlled sphere to selfregulation; assessment of business satisfaction; examination of draft regulatory legal acts; categorization of controlled entities are highlighted as ways to minimize administrative barriers to business during the passage of state control and supervision; as well as systematization of administrative procedures for the implementation of interaction between the state and economic entities.
On the issue of establishing an experimental legal regime in the field of artificial intelligence application
Authors:   lecturer of the Financial university under the Government of the Russian Federation, Barakina E.Y.
Published: August 2021

The article is devoted to the formation of a flexible system of legal regulation in the field of legal regulation of the use of artificial intelligence, which encourages its use and, at the same time, prevents negative consequences. The opinions of Russian and foreign scientists are given. The experience of functioning of regulatory ‘sandboxes’ in other countries is analyzed, as well as their main advantages and disadvantages are identified. Methods of establishing legal norms in the framework of experimental legal regimes are defined.
Correlation of administrative drug-related offences and drug-related crimes: past, present and future
Authors:   Editor-in-Chief, federal scientifi c–practice journal “Narkokontrol”, Honored Lawyer of the Russian Federation, candidate of juridical sciences, professor Correlation of administrative drug-related offences and drug-related crimes: past, present and future, Fedorov Aleksandr Vyacheslavovich
Published: August 2021

The article concerns issues of correlation of administrative drug-related offences and drug-related crimes; substantiates the conclusion that administrative drug-related offences and drug-related crimes have a feature of public danger and the criteria for delimitation thereof are of a conditional and formal character. The author notes the dynamic character of correlation of administrative drug-related offences and drug-related crimes and the tendency to increase the number of administrative drug-related offences and crimes. The attention is drawn to the phenomenon of reciprocity of certain administrative drug-related offences and crimes when actions similar by the objective side are reflected both in the Criminal Code of the RF and the Code of Administrative-Law Offences of the RF. The author analyses the legislation of the People’s Republic of China and the Kingdom of Spain related to criminal responsibility of juridical persons for drugrelated crimes. Taking into consideration foreign practices the author considers the issue of necessity of adding to the administrative responsibility of juridical persons for drug-related offences of a new type of responsibility — criminal responsibility of juridical persons.
Festiwale jako środek kształtowania wizerunku miasta wśród studentów — wstępne propozycje badawcze
Authors: Karpinska-Krakowiak Malgorzata
Published: August 2021

Celem artykułu jest przedstawienie ogólnych ram teoretycznych dla badań w zakresie budowania wizerunku miasta wśród społeczności akademickiej poprzez wydarzenia (a w szczególności poprzez festiwale). Pierwszą część tekstu poświęcono istocie festiwali i ich cechom dystynktywnym. W drugiej części artykułu poprowadzono rozważania nad wizerunkiem miasta, jego podstawowymi komponentami oraz nad dynamiką przemian, jakim wizerunek może ulegać. Natomiast w zakończeniu tekstu zaprezentowano propozycje badawcze w obrębie tematyki kształtowania wizerunku miasta wśród przedstawicieli środowiska akademickiego (studentów) poprzez wydarzenia.
An overview of the concept of marketing orientation in the higher education sector
Authors: Galán Muros Victoria Eugenia , Del Barrio-García Salvador , Luque-Martínez Teodoro
Published: August 2021

This chapter is focused on the concept of marketing orientation in universities through a literature review of the most relevant theoretical contributions, highlighting its definition, approaches and requisites. Marketing oriented universities are explored from both the demand side, presenting the debates on who the customers are, which are their real expectations and demands and how to identify them; and also from the supply side, presenting the main problems and the strategies to increase the value offered. Finally the chapter explains the main consequences that the successful application of marketing can provoke in stakeholders’ responses in terms of reputation, value or satisfaction, among other indicators. Consequences for the local and regional environments are also described regarding human capital, knowledge transfers, community services, etc.
Universities and territorial development
Authors: ZUCCHELLA ANTONELLA
Published: August 2021

This contribution aims at highlighting some key issues of the evolutionary process of universities, underlining in particular their role in promoting economic development and local communities. The recent shift in paradigm from the ivory tower to the entrepreneurial university has been dramatic and raises both consensus and criticism. This research proposes that this evolutionary process does not entail the emergence of one model of university, on the contrary, it entails the emergence of differentiated models. These possible models can be outlined along the two strategic dimensions of geographic orientation (local, global, glocal) and core activity (teaching, research, both). The glocal university addresses contemporarily the needs and opportunities provided by the local environment together with those deriving from the global one. They develop a two tier system of ties, both local and global, thus enhancing the exposure of the local society and economy to the influence of external knowledge. This contribution proposes a model where a more complex role of universities is highlighted and the “entrepreneurial and technological” paradigm — as suggested by the triple helix model — is complemented by a more comprehensive role, which portraits universities as catalyser of local development also in human and social sciences. Moreover, universities characterise — in some cases distinctively — the urban environment and landscape, thus activating tourists flows, generate a local “culture” not only in terms of goods but also of events and activities, of people and buzz and contribute to connect the local system to the global ones.
Epidémiologie des parasites des ovins de la zone Sud forestière de la Côte d'Ivoire
Authors: Komoin Oka C. , Zinsstag Jakob , Pandey V.S. , Fofana F. , N'Depo A.
Published: August 2021

Une étude épidémiologique du parasitisme des ovins de race Djallonké a été menée en Côte d’Ivoire, dans la zone sud forestière qui bénéficie d’un climat tropical. Six moutons ont été autopsiés tous les mois durant deux années, d’août 1994 à juillet 1996 (n = 145). La faune parasitaire comportait neuf espèces de nématodes qui étaient, par ordre de prévalence, Trichostrongylus colubriformis  (89,7 p. 100), Haemonchus contortus (84,1 p. 100), Strongy- loides papillosus (49,7 p. 100), Cooperia curticei (42,1 p. 100), Oesophago-stomum columbianum (25,5 p. 100), Gaigeria pachyscelis (20,2 p. 100), Trichostrongylus axei (11,7 p. 100), Trichuris globulosa (11,7 p. 100) et Bunostomum trigonocephalum (2,1 p. 100). Elle comportait également trois cestodes (Moniezia benedeni, M. expansa et Cysticercus tenuicollis) et trois trématodes (Paramphistomum spp., Dicrocoelium hospes et Fasciola gigantica). Les autres parasites observés au cours de l’étude étaient des coccidies, des microfilaires, des protozoaires (Babesia ovis, Trypanosoma brucei, T. congolense et T. vivax) et des œstres (Oestrus ovis). Des variations saisonnières du parasitisme ont été mises en évidence, mais sans hypobiose larvaire. Les intensités parasitaires et l’excrétion d’œufs d’helminthes sont restées modérées tout au long de l’année. Les animaux âgés de moins d’un an et les mâles avaient des intensités plus élevées que les autres ovins. Un schéma de prophylaxie antiparasitaire est proposé.
Hormones thyroïdiennes iodées libres plasmatiques chez le dromadaire
Authors: El Khasmi Mohammed , Derouiche A.F. , Riad Fouad , Benouhoud M. , Davicco Marie Jeanne , Coxam Véronique , Safwate Abdallah , Barlet J.P.
Published: August 2021

Les taux plasmatiques de thyroxine libre (FT4) et de triiodothyronine libre (FT3) ont été mesurés chez 30 dromadaires mâles adultes, chez 31 chamelles non gravides et non allaitantes et chez 13 chamelles et leur fœtus de 6 mois ou leur nouveau-né, de la naissance à l’âge de 30 jours. Les valeurs basales de FT4 et de FT3 plasmatiques (pM) chez le dromadaire mâle adulte ont été respectivement de 24,8 ± 2,8 et 8,6 ± 1,4. Au cours de la gestation (6 mois), ces valeurs (pM) ont été respectivement de 43,4 ± 4,1 et 1,4 ± 0,4 chez le fœtus, et de 31,1 ± 2,8 et 16,9 ± 2,1 chez la chamelle. Chez le chamelon, les taux de FT4 (50,7 ± 4,1) et de FT3 (18,6 ± 2,3) plasmatiques (pM), très élevés à la naissance, ont diminué progressivement jusqu’au 7e jour (FT4 : 28,3 ± 2,8 ; P < 0,05 ; FT3 : 9,6 ± 1,7 ; P < 0,05), puis sont restés stables jusqu’au 30e jour. L’évolution périnatale et postnatale des taux de FT4 et de FT3 plasmatiques chez la chamelle et son chamelon était similaire à celle rapportée chez les autres ruminants domestiques.
The Profiles of Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) Patients in Tertiary Hospital
Authors: Isaac William Andrew , Damayanti Damayanti , Fatimah Nurmawati , Hidayati Afif Nurul
Published: August 2021

Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe eruptive skin reactions that can cause death. The incidence of SJS and TEN cases in the United States is 1.5–9.6 per 1,000,000 per year. Drugs are the primary etiology of SJS and TEN. Some drugs are at high risk and used frequently. The SJS and TEN mortality rates were relatively high, with SJS 4.8%, SJS / TEN overlap 19.8%, and TEN 14.8%. In Indonesia, there are lack of studies on the SJS and TEN. This study is needed to determine the epidemiological profile of SJS and TEN. Purpose: This study aimed to describe SJS and TEN patients' profiles. Methods: Drug-induced SJS and TEN cases from January 2016 to December 2019 were evaluated from the medical records patients' profile, incidence, suspected drugs, risk factors, and comorbidities of SJS and TEN were described. Result: There were 28 SJS and TEN patients, comprising of 24 SJS patients (85.7%), 3 TEN patients (10.7%), and 1 SJS overlapping TEN patients (3.5%). The most common suspected drugs were paracetamol (22.2%), carbamazepine (20.4%), cefadroxil (8.8%), and ciprofloxacin (8.8%). Women (53.5%) experienced more severe drug eruptions than men (46.4%). The largest age group was 25–44 years (35.7%). Most comorbidities were epilepsy (21%), diabetes (15.7%), hypertension (15.7%), and stroke (15.7%). Conclusion: The most common manifestation was SJS with paracetamol as the most common suspected drug, followed by carbamazepine.
Rheological Study of an Extruded Fish Diet with the Addition of Hydrolyzed Protein Meal
Authors: Hoyos-Concha José Luis , Villada-Castillo Hector Samuel , Fernández-Quintero Alejandro , Ortega-Toro Rodrigo
Published: August 2021

The extrusion of food for human and animal consumption is a unit operation that includes mixing, shearing and force to the materials related to the rheological properties of the materials in the extruder. The present work aims to study the rheological behavior of an extruded fish diet incorporating hydrolyzed protein flour processed by extrusion. The measurement was carried out online with a slit die rheometer, defining the rheological models and parameters that fit the process. During the extrusion process, the raw materials used were hydrolyzed protein meal, fish meal and cassava starch. For the results, the evaluated treatments were adjusted to the Power Law, where an increase in the shear rate decreases the viscosity of the material, corresponding to a pseudoplastic behavior. The incorporation of hydrolyzed protein flour presented a significant effect on the value of n and Klp, increasing the viscosity with the increase in the percentage of inclusion of HPH. The models obtained for the prediction of the viscosity are adjusted to the changes in shear rate, temperature and humidity of the system.
Iodine in a Nutshell: What Do You Need to Know?
Authors: Alotaibi Fahad Awwadh
Published: August 2021

When you type” Iodine” in google scholar, you will end up with 2,200,000 articles that are titled with anything regarding iodine, except “what is it”. Here in this short note review, a summary of iodine that includes its origin, structure, types, sources, uses, concentration, toxicity, and iodine intake and how to measure it, was collected and infused in a nutshell.
Assessing the student academic workload in the learning process of a technical university
Authors: Ibatova Aygul Z.
Published: August 2021

The article deals with an assessment of the students' workload influence on the academic progress in a technical university. This study was carried out at Tyumen Industrial University, the Branch of IUT in Surgut. The research participants were the first-year students of full-time and part-time departments of the "Oil and Gas Business" direction. The research was done in 2017-2018. Much attention is given to some of the consequences that first-year students have: neuropsychic stress, declining academic progress, and the quality of education. There are reasons for such a state: lack of time, a large amount of information, many classroom hours, irregular distribution of the students' workload intensity of academic disciplines in the first semester, etc. The research gives valuable information on the necessity to improve the system of students' organizational and educational activities, depending on the specific features of a technical university. This study contributes to the existing research on the impact of academic workload on the students' emotional, mental state in higher education. Specifically, it studies the volume of the freshmen's academic workload in accordance with the curriculum, which is one of the main negative factors affecting the level of mental students' performance.
Preparing personnel for a successful perception and assembly of the course of mathematics at the technical university
Authors: Ilyashenko Lubov K. , Belov Dmitriy A.
Published: August 2021

Scientific and technological progress, digitalization of the economy, as well as all other spheres of human life, require qualified personnel. Technology, however, simplifies everyday life and gives students plenty of opportunities to enroll in college and not study at all. This study's main purpose is to investigate this paradox, instill in student's love, positive motivation to study mathematics, and encourage them to complete their learning tasks. The research method is a survey of first-year students of the fields of study "Oil and Gas Business" and "Technosphere Safety" of Tyumen Industrial University to identify the motivation for their study of the university mathematics program. It was found that at the moment, it is easier for students to find a calculating job than to do it themselves, that the perception of mathematics as a subject in the first year affects not only further academic performance in the university but also the entire professional life of a person. To solve the problem of motivating first-year students to study mathematics, as we have found out, it is possible if: use the "first type" of motivation, which consists in the fact that is influencing the student, cause certain internal motives prompting to study mathematics; take into account the age and individual characteristics of students and each new stream in general.
Pengaruh Model Pembelajaran Creative Problem Solving (CPS) dalam Pembelajaran Jarak Jauh (PJJ) terhadap Kemampuan Berpikir Kritis Matematis Siswa
Authors: Maharani Nabilla , Hadiyan Aris , Murdiyanto Tri
Published: August 2021

Penelitian ini bertujuan untuk mengetahui terdapat atau tidaknya pengaruh model pembelajaran Creative Problem Solving (CPS) dalam Pembelajaran Jarak Jauh (PJJ) terhadap kemampuan berpikir kritis matematis peserta didik. Penelitian ini merupakan penelitian kuantitatif dan menggunakan metode penelitian eksperimen jenis quasi-experiment. Populasi Penelitian ini adalah seluruh peserta didik kelas X SMAN 14 Bekasi. Sampel yang diteliti sebanyak 72. Teknik pengambilan sampel menggunakan teknik Cluster Random Sampling. Dalam penelitian ini pengumpulan data menggunakan instrumen kemampuan berpikir kritis matematis. Uji coba instrumen dilakukan di SMAN 14 Bekasi. Sebelum data dianalisis, terlebih dahulu dilakukan uji persyaratan yaitu uji normalitas dengan menggunakan uji Lilliefors, dan homogenitas dengan menggunakan uji Fisher. Berdasarkan hasil analisis menggunakan uji-t menghasilkan t_hitung sebesar 5,385 dan t_tabel sebesar 1,66 yang mengakibatkan H0 ditolak pada taraf signifikan 0,05 dengan Effect Size sebesar 1,269 yang tergolong kategori large. Oleh karena itu, hasil penelitian ini memiliki kesimpulan bahwa terdapat pengaruh model pembelajaran Creative Problem Solving (CPS) dalam Pembelajaran Jarak Jauh (PJJ) terhadap kemampuan berpikir kritis matematis peserta didik.
Perception Analysis Of PNJ Civil Engineering Students Toward Main Course Using Importance Performance Analysis Method
Authors: Amalia Amalia , Hasan Muhammad Fathur Rouf , Yanuarini Erlina , Setiawan Yanuar , Saputra Jonathan
Published: August 2021

The suitability between expectations and reality of the quality of education students get during college affects students' perceptions of education quality in a study program. Information on the achievement of the implementation of main courses subjects and the teaching and learning process can be used as a basis for evaluating and mapping the gaps between the curriculum and the teaching and learning process with the required competencies. This study aims to determine students' perceptions of core subjects' learning outcomes in the D3 KS and D3 KG Pograms, Department of Civil Engineering PNJ. The method used in this research is the survey method, with purposive random sampling and descriptive analysis approach. Meanwhile, the performance and gap analysis use the Importance-Performance Analysis (IPA) method. The results denote that the students' perceptions of the learning outcomes of the main courses of the D3 KG and D3 KS Programs, Department of Civil Engineering PNJ showed promising results. The IPA analysis shows that six of the seven D3 KG Study Program main courses are in Quadrant II, and six of the eight D3 KS Program main courses are also in Quadrant II.
In situ measurements of directional wave spectra from an unmanned aerial system
Authors: Collins Clarence , Brodie Katherine
Published: August 2021

This Coastal and Hydraulics Engineering Technical Note (CHETN) describes the ability to measure the directional-frequency spectrum of sea surface waves based on the motion of a floating unmanned aerial system (UAS). The UAS used in this effort was custom built and designed to land on and take off from the sea surface. It was deployed in the vicinity of an operational wave sensor, the 8 m* array, at the US Army Engineer Research and Development Center (ERDC), Field Research Facility (FRF) in Duck, NC. While on the sea surface, an inertial navigation system (INS) recorded the response of the UAS to the incoming ocean waves. Two different INS signals were used to calculate one-dimensional (1D) frequency spectra and compared against the 8 m array. Two-dimensional (2D) directional-frequency spectra were calculated from INS data using traditional single-point-triplet analysis and a data adaptive method. The directional spectrum compared favorably against the 8 m array.
Environmental Stressors and Well-Being on Middle-Aged and Elderly People: The Mediating Role of Outdoor Leisure Behaviour and Place Attachment
Authors: Yuan Kuo-Shu , Wu Tung-Ju
Published: August 2021

This study develops a relational model of how environmental stressors, place attachment, and outdoor leisure are related to urban green zones and accordingly, Fujian Province in China is studied as our case problem. The research participates primarily middle-aged and elderly residents. In total, 871 valid questionnaires are retrieved. Structural equation modelling and path analysis are used to verify the model’s fitness. The results indicate that environmental stressors and outdoor leisure are significantly negatively correlated. In addition, the outdoor leisure and place attachment are significantly positively correlated. As such, the place attachment and well-being are significantly positively correlated. However, the place attachment and outdoor leisure mediated the relationship between environmental stressors and well-being. The mediating path indicated that middle-aged and elderly residents face severe environmental stressors and will engage in a few outdoor leisure activities, resulting in low well-being. Furthermore, when middle-aged and elderly residents face severe environmental stressors, they have increased place attachment, thereby increasing their well-being. The findings can serve as a reference for environmental management agencies and future researchers.
Dietary Intakes in Pregnant Women with Previous Bariatric Surgery
Authors: Gagnon Geneviève , Carreau Anne-Marie , Plante Anne-Sophie , Savard Claudia , Lemieux Simone , Weisnagel S. John , Gagnon Claudia , Veillette Johanne , Michaud Andréanne , Marceau Simon , Biertho Laurent , Tchernof André , Morisset Anne-Sophie
Published: August 2021

Purpose: To 1) compare dietary intakes of pregnant women with previous bariatric surgery with the Dietary reference intakes (DRIs); 2); compare their dietary intakes as well as their diet quality with a control group of pregnant women with no history of bariatric surgery. Methods: Twenty-eight (28) pregnant women with previous surgery (sleeve gastrectomy, n=7 and biliopancreatic diversion with duodenal switch, n=21) were matched for pre-pregnancy body mass index with 28 pregnant women with no history of surgery. In at least one trimester, participants completed a minimum of 2 Web-based 24-h dietary recalls from which energy, macro- and micronutrient intakes as well as the Canadian Healthy Eating Index (C-HEI) were derived. Results: No differences were observed for energy intake between groups. All women had protein intakes within the recommended range, but most women with previous surgery had carbohydrate (67 %) and dietary fiber intakes (98 %) below recommendations. In both groups, mean total fat, saturated fatty acids, free sugars and sodium intakes were above recommendations, as opposed to mean vitamin D, folic acid and iron dietary intakes below recommendations for most women. Compared with the control group, pregnant women with previous bariatric surgery had lower overall C-HEI scores. Conclusion: These results suggest that pregnant women with previous bariatric surgery would benefit from a nutritional follow-up throughout their pregnancy.Level of evidenceLevel III: Evidence obtained from well-designed cohort or case-control analytic studies
MicroRNA-1246 Suppresses the Metastasis of Breast Cancer Cells by Targeting the DYRK1A/PGRN Axis to Prevent The Epithelial-Mesenchymal Transition
Authors: Wang Pan , Chen Wenju , Zhang Yaqiong , Zhong Qianyi , Li Zhaoyun , Wang Yichao
Published: August 2021

Objective. Breast cancer is one of the most common malignant and highly heterogeneous tumors in women. MicroRNAs (miRNAs), such as miR-1246, play important roles in various types of malignant cancers, including triple-negative breast cancer (TNBC). However, the biological role of miR-1246 in TNBC has not yet been fully elucidated. In this study, we studied the role of miR-1246 in the occurrence and development of TNBC and its mechanism of action.Methods. Cell Counting Kit-8 (CCK-8), wound healing, and Transwell assays were performed to observe the effects of miR-1246 on TNBC cell proliferation, migration, and invasion, respectively. The expression of epithelial-mesenchymal transition (EMT) markers was detected by western blotting. Dual luciferase reporter assays were performed to determine whether DYRK1A is a novel target of miR-1246. In addition, an immunoprecipitation experiment was performed to verify the binding of DYRK1A to PGRN. Rescue experiments were performed to determine whether DYRK1A is a novel target of miR-1246 and whether miR-1246 suppresses the metastasis of breast cancer cells by targeting the DYRK1A/PGRN axis to prevent the epithelial-mesenchymal transition.Results. Our results show that miR‑1246 suppresses the proliferation, migration, and invasion of TNBC cells and that DYRK1A is a novel target of miR-1246. MiR‑1246 plays a suppressive role in the regulation of the EMT of TNBC cells by targeting DYRK1A. DYRK1A mediates the metastasis of triple-negative breast cancer via activation of the EMT. We identified PGRN as a novel DYRK1A-interacting protein. DYRK1A and PGRN act together to regulate the occurrence and development of breast cancer through miR-1246.Conclusion. miR-1246 attenuates TNBC cell invasion and the EMT by targeting the DYRK1A/PGRN axis. Our data suggest that miR‑1246 may be used to develop novel early-stage diagnostic and therapeutic strategies for TNBC.
Building a Country-Wide Fistula Treatment Network in Kenya: Results From the First Six Years (2014-2020)
Authors: Pollaczek Lindsey , Ayadi Alison M. El , Mohamed Habiba C.
Published: August 2021

It is estimated that one million women worldwide live with untreated fistula, a devastating injury primarily caused by prolonged obstructed labor when women do not have access to timely emergency obstetric care. Women with fistula are incontinent of urine and/or feces and often suffer severe social and psychological consequences such as profound stigma and depression. Obstetric fistula affects economically vulnerable women and garners little attention on the global health stage. Exact figures on fistula incidence and prevalence are not known. In Kenya, results from a population-based survey suggest that approximately 120,000 reproductive-aged women have experienced fistula-like symptoms.In 2013, Fistula Foundation designed a program to significantly increase country-wide fistula treatment capacity in Kenya by addressing key barriers that limit women’s ability to receive treatment. Launched as Action on Fistula, and later becoming the Fistula Treatment Network, this model created a network of hospitals, a training center for surgeons and healthcare providers, and robust community outreach and reintegration activities. The Fistula Treatment Network was implemented by Fistula Foundation in collaboration with the Ministry of Health and Kenyan non-governmental and community-based organizations. Fistula Foundation and its donors provided the program’s funding, with seed funding, representing about 30% of the program budget, provided by Astellas Pharma EMEA.Over a six-year period, 2014-2020, the network supported 6,223 surgeries at seven hospitals, established a fistula training center and trained eleven surgeons, trained 424 Community Health Volunteers, conducted extensive outreach to all 47 counties in Kenya, and contributed to the National Strategic Framework to End Female Genital Fistula. At 12 months post fistula repair, 96% of women in a community setting reported that they were dry and not experiencing any incontinence and the proportion of women reporting normal functioning increased from 18% at baseline to 85% at twelve-months. The Fistula Foundation’s Fistula Treatment Network model increased access to fistula care services, strengthened the healthcare workforce, improved understanding of fistula and reduced stigma in a community setting. This integrated approach is an effective and replicable model for building capacity to deliver comprehensive fistula care services in other countries where the burden of fistula is high.
Characteristics of the Disastrous Debris Flow of Chediguan Gully in Yinxing Town, Sichuan Province, on August 20, 2019
Authors: Ning Li , Chuan Tang , Xianzheng Zhang , Ming Chang , Zhile Shu , Xianghang Bu
Published: August 2021

On August 20, 2019, at 2 a.m., a disastrous debris flow occurred in Chediguan gully in Yinxing town, China. The debris flow destroyed the drainage groove and the bridge at the exit of the gully. In addition, the debris flow temporarily blocked the Minjiang River during the flood peak, flooding the Taipingyi hydropower station 200 m upstream and leaving two plant workers missing. To further understand the activity of the debris flow after the Wenchuan earthquake, the characteristics of this debris flow event were studied. Eleven years after the Wenchuan earthquake, a disastrous debris flow still occurred in the Chediguan catchment, causing more severe losses than those of earlier debris flows. In this paper, the formation mechanism and dynamic characteristics of this debris flow event are analysed based on a drone survey, high-definition remote sensing interpretations and other means. The catastrophic debris flow event indicates that debris flows in the Wenchuan earthquake area are still active. A large amount of dredging work in the main gully could effectively reduce the debris flow risk in the gully. In addition, it is also important to repair or rebuild damaged mitigation measures and to establish a real-time monitoring and early warning system for the high-risk gully.
Glia Maturation Factor-γ (GMFG) Promotes Ovarian Tumorigenesis and Chemoresistance via Activation of the FAK Signaling-Associated Focal Adhesion Dynamics
Authors: Lan Aihua , Wang Jingshu , Lv Cuiting , Yang Lina , Du Ran , Li Hui , Yu Yinjue , Ren Chunxia , Yang Gong
Published: August 2021

Background: Glia maturation factor-γ (GMFG) is reported to regulate actin cytoskeleton remodeling through the facilitation of actin debranching and nucleation suppression, which may be associated with cellular malignancy, but the role of GMFG in tumorigenesis remains largely unknown. Methods: By overexpression or silencing of GMFG in ovarian cancer cell lines, we show that GMFG enhances in vitro ovarian cancer cell proliferation, migration, invasion, and paclitaxel resistance and accelerates in vivo tumor growth and intraperitoneal metastasis in xenograft animal models. Results: The mechanistic study demonstrates that GMFG activates the FAK/Talin/Paxillin/Src signaling molecules via binding to p-FAK (Tyr397) and p-Talin (Ser425), whereas cell proliferation, migration and paclitaxel resistance induced by GMFG can be inversely suppressed by the chemical inhibition of p-FAK (Tyr397). Additionally, patients with high expression of GMFG exhibited a poor progression-free survival (PFS) (HR = 1.2, 95%CI: 1.05−1.37, P = 0.0069), and were significantly correlated with lymph node metastasis (P = 0.002) and venous invasion (P = 0.028). Conclusion: Our study suggests that GMFG may activate FAK signaling via binding to p-FAK (tyr397) and p-Talin (ser425) to promote ovarian tumorigenesis and chemoresistance. These findings indicate a functional interaction between GMFG and FAK pathway in ovarian tumorigenesis and chemoresistance. Thus, targeting the oncogenic GMFG-FAK axis may be a promising therapeutic strategy for ovarian cancer.
Spatial Maps of Hepatocellular Carcinoma Transcriptomes Highlight an Unexplored Landscape of Heterogeneity and a Novel Gene Signature for Survival
Authors: Zhao Nan , Zhang Yanhui , Cheng Runfen , Zhang Danfang , Li Fan , Guo Yuhong , Qiu Zhiqiang , Dong Xueyi , Ban Xinchao , Sun Baocun , Zhao xiulan
Published: August 2021

Background: Hepatocellular carcinoma (HCC) are often present with satellite nodules, rendering current curative treatments ineffective in many patients. The heterogeneity of HCC is a major challenge in personalized medicine. The emergence of spatial transcriptomics (ST) provides a powerful strategy for delineating the complex molecular landscapes of tumors. Methods: In this study, we investigated tissue-wide gene expression heterogeneity in tumor and adjacent nonneoplastic tissues using ST technology. We analyzed the transcriptomes of nearly 10820 tissue regions and identified main gene expression clusters and their specific marker genes (differentially expressed genes, DEGs) in patients. The DEGs were analyzed from two perspectives. First of all, we identified two distinct gene profiles associated with satellite nodules and conducted a more comprehensive analysis for both gene profiles. Their clinical relevance for human HCC was validated with KM Plotter. Secondly, we screened DEGs with TCGA database to divide the HCC cohort into high- and low-risk groups according to Cox analysis. HCC patients from the ICGC cohort were used for validation. Kaplan Meier analysis was used to compare the overall survival (OS) between high- and low-risk groups. Univariate and multivariate Cox analyses were applied to determine the independent predictors for OS. Results: Novel markers for the prediction of satellite nodules and a tumor clusters specific marker genes signature model(6 genes) for HCC prognosis was constructed, respectively. Conclusion: The establishment of marker gene proﬁles may be an important step towards an unbiased view of HCC and the 6-genes signature can be used for prognostic prediction in HCC. This analysis will help us to clarify one of the possible soucres of HCC heterogeneity, uncover pathogenic mechanisms and novel anti-tumor drug targets.