bluuebunny/crossref_metadata_2025 huggingface dataset:
Sanksi Pidana Terhadap Pelaku Tindak Pidana yang Mengalami Gangguan Kejiwaan
Authors: Putu Wisesa Sagara  , Anak Agung Sagung Laksmi Dewi  , Luh Putu Suryani
Published: September 2024

Pelaksanaan proses peradilan pidana didasarkan pada Sistem Peradilan Pidana Terpadu (KUHAP). Tindak pidana gangguan jiwa berkaitan dengan Pasal 44 KUHP. Ilmu forensik dibutuhkan untuk pembuktian secara ilmiah terhadap pelaku tindak pidana yang mengalami gangguan jiwa. Dalam hal ini penulis mengambil rumusan masalah sebagai berikut 1) Bagaimana Pengaturan Hukum tindak pidana yang dilaksanakan oleh pelaku dengan gangguan kejiwaan? 2) Bagaimana sanksi pidana terhadap pelaku tindak pidana dengan gangguan kejiwaan? Metode penelitian ini yakni hukum normatif. Hasil penelitian pengaturan hukum terhadap orang dengan gangguan jiwa diatur pada pasal 44 ayat 1 dan 2 beserta pasal 49 ayat 1. Hukuman pidana tidak berlaku bagi pelaku kejahatan yang dilaksanakan oleh individu dengan gangguan jiwa. Hakim bisa menjatuhkan putusan sesuai hukum yang terungkap dan penjatuhan sanksi pidana terhadap pelaku tindak pidana yang mengalami kejahatan gangguan kejiwaan yang diatur dalam peraturan Perundang-Undangan dan tetap memperhatikan juga hak asasi manusia yang dimiliki oleh manusia sejak lahir sesuai ketentuan peraturan Perundang-Undangan mengenai hak asasi manusia.
Pemberian Fasilitas Ekspor Crude Palm Oil Oleh Dirjen Perdagangan Luar Negeri Ditinjau dari Undang â€“ Undang Tindak Pidana Korupsi
Authors: I Kadek Yukik Okta Dwipayana  , I Nyoman Gede Sugiartha  , I Nyoman Sujana
Published: September 2024

Negara Indonesia merupakan negara yang akan kekayaan budayanya disamping itu jumlah populasi masyarakatnya yang tiap hari kian bertambah membuat banyaknya pemikiran berbeda beda tiap orangnya dengan tujuan hidupnya masing â€“ masing. Merupakan negara hukum, Indonesia memiliki beberapa komponen yang khusus mendalami tentang hukum itu sendiri mulai dari pengaturannya hingga sanksinya yang membuat tingkah laku masyarakat dibatasi oleh hukum dan disisi lain dengan adanya hukum masyarakat menjadi lebih terkontrol dan mengurangi perilaku yang melanggar norma yang dilakukan. Korupsi merupakan tindak pidana paling banyak penggemarnya sedari jaman revolusi karena pengaturannya sendiri tidaklah ketat dan kerap berubah â€“ ubah sehingga menjadikan seseorang dengan mudah dapat melakukan tindakan korupsi. Penelitian yang dilakukan penulis berkaitan dengan tindak pidana korupsi dimana korupsi ini sendiri dilakukan oleh seorang pejabat yang memiliki wewenang tertentu di bidangnya dan mendapat kepercayaan penuh dari pemerintah dan karena kewenangannya tersebut mempermudah melakukan perbuatan yang merugikan bangsa dan negara.
Konsep Hukum pada Gugatan Kasus Perdata Wanprestasi Akibat Kredit Macet
Authors: Muhammad Fadillah Ulhad  , Maria Amelia
Published: September 2024

Gugatan adalah suatu tuntutan hak yang bertujuan untuk memperoleh perlindungan hak yang diberikan oleh pengadilan, salah bentuk gugatan yang banyak diajukan adalah gugatan wanprestasi, wanprestasi adalah bentuk tidak dipenuhinya kewajiban dari apa yang telah disepakati dalam perjanjian, bentuk wanprestasi dalam perjanjian memiliki berbagai macam salah satunya ialah kredit macet. Tujuan penelitian ini adalah untuk mengetahui aturan hukum yang ada mengenai gugatan kasus perdata pada perkara wanprestasi serta mengetahui konsep gugatan kasus perdata tentang wanprestasi akibat kredit macet yang terdapat pada perkara dengan nomor register 9/Pdt.G.S/2021/PN Bta. Penelitian ini menggunakan metode yuridis normatif, dengan pendekatan statute approach dan conceptual approach. Jenis penelitian ini dilakukan secara kualitatif, dengan spesifikasi penelitian yang bersifat deskriptif analisis. Data yang digunakan adalah data sekunder yang diperoleh melalui studi kepustakaan. Berdasarkan hasil penelitian ini adalah bahwa jenis gugatan yang lazim diajukan di Peradilan Umum yaitu gugatan wanprestasi. wanprestasi menurut KUH Perdata timbul dari perjanjian (agreement). Lalu berdasarkan kajian konsep hukum terhadap kasus gugatan wanprestasi dengan nomor register perkara 9/Pdt.G/2021/PN Bta ditarik benang merah bahwa pemenuhan syarat formil dan syarat substansi dan pemenuhan unsur dari suatu tindakan yang akan digugat memegang peranan besar dalam kunci keberhasilan suatu gugatan diterima atau ditolak.
Kesadaran Hukum Orang Tua tentang Hak-Hak Anak: Faktor Penyebab Anak Bekerja pada Sektor Informal
Authors: Orpa J. Nubatonis  , Yossie M.Y. Jacob  , Chatryen M. Dju Bire
Published: September 2024

Anak mempunyai sejumlah hak seperti mengenyam pendidikan, bermain dan bergaul, dipenuhi kebutuhan-kebutuhan primernya. Masa kecilnya harus diisi dengan berbagai kegiatan positif serta berguna bagi kehidupan anak di masa depan. Misalnya, bermain dan bergaul, mengikuti pendidikan formal maupun pendidikan nonformal. Dengan demikian, anak akan menjadi manusia yang berkepribadian ideal sebagaimana diharapkan. Anak juga memiliki nilai-nilai tertentu dalam keluarga, masyarakat, bangsa dan negara. Misalnya, (1) anak merupakan penerus keturunan; (2) anak membantu ayah-ibu di hari tua; (3) anak membantu menyelesaikan program kerja pembangunan di desa atau kelurahan; (4) anak sebagai pemimpin di masa depan. Tujuan penelitian ini adalah untuk mengetahui kesadaran hukum orang tua tentang hak-hak tentang hak anak dan factor penyebab anak bekerja pada sector informal. Metode penelitian ini adalah metode penelitian jenis empiris. Berdasarkan hasil penelitian dalam kenyataan, tidak semua anak mengalami atau menjalani kehidupan sebagaimana diharapkan. Fakta yang terlihat dalam masyarakat, ada cukup banyak anak yang bekerja di sektor informal. Tempat anak-anak tersebut melakukan pekerjaannya sering sangat berbahaya dan membawa dampak yang sangat buruk bagi masa depan anak. Anak akan menjadi orang yang tidak berpendidikan. Misalnya, mereka sulit sekali mendapatkan pekerjaan yang layak, atau sulit menyesuaikan diri dengan norma-norma yang berlaku dalam masyarakat. Selanjutnya, hal ini akan menimbulkan banyak masalah sosial lainnya dalam masyarakat. Apabila bergaul dengan lingkungan yang buruk, anak-anak ini dapat menjadi penjahat atau sampah masyarakat.
Peran Satuan Polisi Pamong Praja Dalam Penanggulangan Gelandangan dan Pengemis Untuk Memajukan Sektor Pariwisata (Studi Kasus: Kantor Satpol Pp Kota Denpasar)
Authors: Anak Agung Ngurah Bagus Raditya Wikananta  , I Gusti Bagus Suryawan  , Luh Putu Suryani
Published: September 2024

Sektor pariwisata merupakan sektor utama yang mempengaruhi pendapatan daerah Kota Denpasar. Salah satu permasalahan yang dapat mengganggu sektor pariwisata Kota Denpasar ialah gelandangan dan pengemis yang jumlahnya semakin meningkat di kawasan Kota Denpasar. Hal ini memicu rendahnya tingkat ketertiban, keamanan, dan kenyamanan kota. Meningkatnya jumlah gelandangan dan pengemis disebabkan oleh adanya arus urbanisasi ke kota. Tujuan penelitian ini adalah untuk mengetahui bagaimana peranan satpol PP dalam Peraturan Daerah Kota Denpasar Nomor 1 Tahun 2015 mengenai Ketertiban Umum dalam menertibkan gelandangan dan pengemis guna memajukan sektor pariwisata, dan apa saja faktor penghambat yang dihadapi Satpol PP dalam menertibkan gelandangan dan pengemis di Kota Denpasar. Penelitian ini menggunakan penelitian hukum empiris merupakan metode penelitian yang digunakan dalam penelitian ini untuk menjawab permasalahan tersebut, dengan melakukan kajian lanjutan dari peraturan tertulis. Berdasarkan hasil penelitian ini erat kaitannya dengan penertiban gelandangan dan pengemis yang termuat dalam Peraturan Daerah Kota Denpasar Nomor 1 Tahun 2015 mengenai ketertiban umum.
Tanggung Jawab Direksi Terkait Penerapan Good Corporate Governance Terhadap Non Performing Loan Pada Bank Perkreditan Rakyat
Authors: Frederika Ni Made Dwita Noviyanti  , I Made Arjaya  , Desak Gde Dwi Arini
Published: September 2024

Penerapan Good Corporate Governance menjadi tugas dan kewajiban direksi atas pengurusan perseroan Bank. Penelitian ini bertujuan untuk mengetahui dan memahami dampak penerapan Good Corporate Governance serta tanggung jawab sebagai direksi Bank Perkreditan Rakyat. Manfaat penelitian ini untuk menambah pengetahuan mengenai penerapan Good Corporte Governance. Penelitian ini menggunakan penelitian hukum empiris. Berdasarkan hasil penelitian yang diperoleh: Penerapan Good Corporate Governance berdampak besar bagi kesehatan bank, dilihat dari angka persentase Non Performing Loan yang menjadi penilaian bank dan direksi bertanggung jawab penuh dalam melaksanakan tugasnya sesuai dengan peraturan internal bank. Dapat ditarik kesimpulan, dampak penerapan Good Corporate Governance dilihat dari perbedaan persentase Non Perfoming Loan pada masing-masing bank dan direksi bertanggung jawab dengan mendasarkan pada peraturan internal bank. Saran yang disampaikan: perlu dilakukan pengawasan rutin dan lebih memperhatikan prinsip Good Corporate Governance.
Perlindungan Hukum Bagi Kreditur Dalam Hal Debitur Wanprestasi Atas Perjanjian Kredit Dengan Jaminan Fidusia yang Tidak Didaftarkan (Studi Di Pt. Bank Perkreditan Rakyat Mertha Sedana Sempidi-Badung)
Authors: Ni Made Yunika Andrini  , I Nyoman Putu Budiartha  , Putu Ayu Sriasih Wesna
Published: September 2024

Kredit sebagai salah satu usaha yang bisa dijalankan oleh bank dan dalam pemberian kredit, yang memiliki posisi sebagai kreditur memerlukan adanya jaminan, dan adanya objek jaminan salah satu hal yang paling penting. Jaminan yang dimaksud dapat berupa benda bergerak, seperti fidusia, atau benda tidak bergerak. Benda yang dibebani jaminan fidusia harus didaftarkan agar dapat memberikan perlindungan hukum dan hak yang memadai kepada para pihak. Tujuan dan manfaat penelitian ini adalah untuk mengkaji perlindungan hukum bagi kreditur dalam hal debitur wanprestasi dalam perjanjian kredit dengan jaminan fidusia yang tidak didaftarkan. Pendekatan hukum empiris digunakan dalam penelitian ini.  Perjanjian jaminan fidusia yang terjadi di PT. BPR Mertha Sedana merupakan yang bersifat accesoir dari perjanjian perjanjian pokoknya. Berdasarkan hasil penelitian apabila jaminan fidusia tidak didaftarkan, adapun perlindungan hukum bagi kreditur dalam permasalahan seperti ini bisa dilaksanakan berupa perlindungan hukum secara preventif dan represif. Saran penulis yaitu dalam pelaksanaan perjanjian kredit dengan jaminan fidusia, pihak kreditur sebaiknya mendaftarkan jaminan fidusia tersebut ke kantor pendaftaran fidusia, apabila debitur wanprestasi maka pihak bank akan mendapatkan perlindungan hukum sesuai undang-undang.
Perlindungan Hukum bagi Kreditur dalam Hal Debitur Wanprestasi atas Perjanjian Kredit dengan Jaminan Fidusia yang Tidak Didaftarkan (Studi di PT. Bank Perkreditan Rakyat Mertha Sedana Sempidi-Badung)
Authors: Ni Made Yunika Andrini  , I Nyoman Putu Budiartha  , Putu Ayu Sriasih Wesna
Published: September 2024

Kredit merupakan salah satu layanan yang dapat diberikan oleh bank. Dalam pemberian kredit, kreditur memerlukan jaminan, dan objek jaminan memiliki peran yang sangat penting. Jaminan dapat berupa benda bergerak, seperti jaminan fidusia, atau benda tidak bergerak. Dalam hal jaminan fidusia, pendaftaran jaminan menjadi hal yang krusial untuk memberikan perlindungan hukum dan hak yang memadai kepada semua pihak terkait. Penelitian ini bertujuan untuk mengevaluasi perlindungan hukum bagi kreditur ketika debitur mengalami wanprestasi dalam perjanjian kredit dengan jaminan fidusia yang tidak didaftarkan. Pendekatan hukum empiris digunakan dalam penelitian ini. Perjanjian jaminan fidusia yang terjadi di PT. BPR Mertha Sedana merupakan perjanjian aksesoris dari perjanjian kredit utama. Ketika jaminan fidusia tidak didaftarkan, perlindungan hukum dapat dilakukan dengan cara preventif dan represif. Saran yang penulis berikan adalah dalam pelaksanaan perjanjian kredit dengan jaminan fidusia, pihak kreditur sebaiknya selalu mendaftarkan jaminan fidusia tersebut ke kantor pendaftaran fidusia. Dengan demikian, jika terjadi wanprestasi oleh debitur, pihak bank akan mendapatkan perlindungan hukum sesuai dengan undang-undang yang berlaku.
Tindak Kekerasan Bullying dengan Penganiayaan sesuai dengan Undang-undang Nomor 35 Tahun 2014 tentang Perlindungan Anak
Authors: Ni Komang Triana Diah Mahadewi  , I Nyoman Gede Sugiartha  , I Gusti Agung Ayu Gita Pritayanti Dinar
Published: September 2024

Tindak kekerasan bullying dengan penganiayaan termasuk dalam kategori kekerasan fisik yang sering terjadi di ruang publik dan memiliki dampak yang berbahaya, bahkan dapat berujung pada kematian. Namun, ketidakjelasan dasar hukum dalam penanganan kasus bullying dengan penganiayaan terhadap anak seringkali membuat korban enggan melaporkan ke pihak berwajib, dan masyarakat pun masih sering meremehkan kasus bullying terhadap anak dengan alasan bahwa anak-anak masih terlalu muda untuk memahami benar dan salah. Rumusan masalah dalam penelitian ini adalah: bagaimana pengaturan tindak pidana kekerasan bullying dengan penganiayaan untuk melindungi korban anak? Dan bagaimana sanksi pidana yang diberlakukan terhadap pelaku tindak kekerasan bullying dengan penganiayaan dalam melindungi korban anak? Tujuan dari penelitian ini adalah untuk menganalisis pengaturan dan sanksi tindak kekerasan bullying dengan penganiayaan dalam melindungi korban anak di Indonesia, dengan merujuk pada KUHP dan Pasal 76C Undang-Undang Nomor 35 Tahun 2014 tentang Perlindungan Anak.
Efektivitas E-Court Sebagai Wujud Asas Sederhana, Cepat, dan Biaya Ringan dalam Sistem Peradilan Perdata di Pengadilan Negeri Gianyar
Authors: Ni Luh Gita Saraswati  , I Nyoman Gede Sugiartha  , I G A A Gita Pritayanti Dinar
Published: September 2024

Hukum elektronik atau disebut juga dengan e-court merupakan Inovasi Mahkamah Agung yang membantu prosesperadilan menjadi cepat, mudah dan terjangkau. Rapat Pengadilan Elektronik dengan Mahkamah Agung RepublikIndonesia (PERMA) No. 1 Tahun 2019 tentang Penanganan Perkara Elektronik dan Perkara Peradilan yangmengeluarkan Keputusan No. 3 Tahun 2018 tentang Penanganan Produk Elektronik. Pengenalan e-court ke dalamsistem hukum telah diterima dengan baik oleh masyarakat dan para petingginya, sejalan dengan tujuan e-courtuntuk mendorong terwujudnya puasa yang hakiki dan efektif. implementasi sederhana dan murah. Eksperimenpenerbitan Dalam karya ini, penulis mengkaji metode empirisme hukum, misalnya. Penelitian yang membantuuntuk melihat hukum dalam arti sebenarnya dan konsekuensinya di masyarakat. Fokus penelitian ini adalahPengadilan Negeri Gianyar yang berhasil meraih Penghargaan Manajemen Perkara Terbaik dan WebsitePengadilan/ Keterbukaan Informasi Publik Terbaik dalam Lomba Pelayanan Peradilan Pengadilan NegeriDenpasar. Berdasarkan hal tersebut, penulis menanyakan bagaimana penerapan E-court di Pengadilan NegeriGianyar dalam PERMA 1 Tahun 2019 bertujuan untuk memproses perkara dan beracara secara elektronik danseberapa efektifkah peradilan online di Pengadilan Negeri Gianyar? Pengadilan Negeri Gianyar perlumeningkatkan pelayanan kotamadya. Tujuan dari penelitian ini adalah implementasi e-court pengadilan negerigianyar sesuai dengan peraturan mahkamah agung no.1 tahun 2019 dan efektivitas e-court pengadilan negerigianyar sebagai wujud asas sederhana, cepat dan biaya ringan khususnya dalam peradilan perdata.
Sanksi Pidana Terhadap Anak Yang Melakukan Penganiayaan Terhadap Lansia
Authors: I Putu Gede Krisna Eka Putra
Published: September 2024

Salah satu bentuk kejahatan yang sedang berkembang di masyarakat serta sebuah tindak pidana ialah penganiayaan. Penganiayaan adalah kejahatan yang berkembang dari waktu ke waktu, seperti bisa dilihat dari pelaku bukan orang dewasa tapi anak-anak. Peneliti memaparkan rumusan masalah yaitu bagaimanakah pengaturan hukum terhadap anak yang melakukan tindak pidana penganiayaan terhadap lansia? serta bagaimanakah sanksi pidana kepada anak yang melakukan penganiayaan terhadap lansia? Penelitian ini memakai tipe penelitian hukum normatif sebagai acuan dalam penelitian. Berdasarkan hasil penelitian anak yang melaksanakan perbuatan pidana tergolong hukum yang khusus mengesampingkan hukum umum atau menganut asas lex specialis derogat legi generali. Dasar hukum pemidanaan kepada anak berdasarkan Undang-Undang Nomor 11 Tahun 2012 perihal â€œSistem Peradilan Pidana Anakâ€. Sanksi terhadap anak tidak hanya memberikan sanksi dan efek jera saja namun perlu perlu mendapatkan perlindungan juga terhadap proses rehab, Kesehatan mental serta psikis karena anak merupakan generasi penerus bangsa
Eksistensi Perlindungan Hukum Terhadap Anak Sebagai Akibat Tindak Pidana Pencabulan di Kabupaten Gianyar
Authors: Putri Putu Dyah Agung Mas Narayana , Sepud I Made , Sancaya I Wayan Werasmana
Published: September 2024

Children have limitations in understanding and protecting themselves from various influences of the existing system. When children are involved in legal issues, the state must provide protection to children through laws and regulations including Law Number 11 of 2012 concerning the Juvenile Criminal Justice System. Sexual intercourse with children is an act that is categorized as rape and obscenity, and usually sexual intercourse is carried out by adults to children under the age of 15, therefore the formulation of the problem is raised, namely: 1) What is the legal protection against child victims of sexual abuse in Gianyar Regency? and 2) What are the criminal sanctions against perpetrators of criminal acts of child molestation in Gianyar Regency? This study uses an empirical research type. The results obtained from legal protection for child victims of abuse are that they have received legal protection as stipulated in Law No. 35 of 2014 on amendments to Law No. 23 of 2002 concerning Child Protection. Criminal sanctions obtained by perpetrators of child abuse are a minimum of 3 years and a maximum of 15 years in prison and a minimum fine of Rp. 60 million and a maximum of Rp. 300 million.
Comparing the Effectiveness of Human and AI-Generated Endorsers in Advertising Campaigns
Authors: Akbari Deni Adha , Sumarwan Ujang , Hasanah Nur , Edison Rizki Edmi
Published: September 2024

This review explores the contrasting roles of machine-driven and human endorsers in advertising campaigns, assessing their ability to engage consumer visual attention. With its ability to tailor content and predict consumer responses, the machine-driven approach has brought new dimensions to advertising, though its influence may differ across various demographic groups. Conversely, human endorsers substantially impact consumer decisions because they can form emotional bonds, enhance authenticity, and build trust. The review encourages a perspective that sees machine-driven and human endorsers not as rivals but as complementary forces, with further studies needed to investigate how to combine these elements best.
Autoimplantação de um Sistema de Gestão da Qualidade no Sistema Nacional de Vigilância Sanitária: análise da estratégia utilizada no Projeto Integravisa III
Authors: Da Costa Borysow Igor , Augusta Accioly Varella Barca Danila , Medeiros Santos Claudio , Baeta Silveira Santos Mônica , Madeira da Silva Wilma , Lopes Zanetta Bruno , Duarte da Matta Alex Sander , De Sales Cunha Jonas
Published: September 2024

Introduction: The implementation of quality management systems (QMS) has been a strategy encouraged by the National Health Surveillance Agency (Anvisa) for bodies within the National Health Surveillance System. Objective: This article describes and analyzes a project to support the self-implementation of QMS in state Health Surveillance units (Visas). Method: Experience report, which considered the results of an online activity evaluation questionnaire, answered by Visas workers participating in the project, addressing, among other aspects, facilitating and hindering factors for the self- implementation process in the respective institutions, as a corpus of analysis. Results: The facilitators were teaching material, consultancy, support for self-implementation, and feedback on documents produced to meet the QMS requirements. The obstacles were the lack of structure, time, and maturity of some teams in dealing with the demands of self-implementation, the excess of work resulting from the overlapping of daily activities with the production of documents for quality management, as well as the absence felt by teams that required more faceto-face time with project consultants. Conclusions: The process brought gains to Visas, in general, but it was clear that for the effective continuation of the self-implementation process, commitment and dedication by managers and teams are necessary.
FORMULATION DEVELOPMENT AND CHARACTERIZATION OF ATAZANAVIR SULPHATE CONTROLLED RELEASE NON-EFFERVESCENT FLOATING MATRIX TABLETS
Authors: JADI RAJENDRA KUMAR , Komati Someshwar , Dasi Vishali , Padala Narayana Raju
Published: September 2024

The objective of the present work to develop extended-release floating matrix tablets of ATZ, which were designed to prolong the gastric residence time and drug release after oral administration. Different grades of low-density lipid (i.e. ethylcellulose) and Hydroxypropyl methylcellulose (i.e. HPMC K100M) were used to get the desired floating and prolonged release profile over an extended period. All the formulations extended the drug release up to 24 hours and more and the formulations were optimized for the desired release profiles. The release and floating property depended on the polymer type and polymer proportion. The formulation prepared with EC and HPMC K100M (i.e. 10%, 20%, and 30%) has more floating time than the formulation prepared with the EC alone. The optimized formulation (F10) prepared with a combination of EC N100 and HPMC K100M was evaluated for In vivo radiographic study, which shows the floating property for up to 9 hours. The DSC study shows that there is no drug-polymer interaction. This study gives the preliminary idea about the development of the floating drug delivery systems of Atazanavir without the use of a gas generating agent.
Keywords: Non-effervescent, extended-release, gastric residence time, buoyancy, lipid aid.
Formulation of Rapid Dissolving Films Containing Granisetron Hydrochloride and Ondansetron Hydrochloride
Authors: Khunteta Alok , Gupta Manish Kumar , Swarnkar Surendra Kumar
Published: September 2024

The oral mucosa is conveniently and easily accessible and therefore allows uncomplicated application of dosage forms. A rapid-dissolving drug delivery system, in most cases, is a tablet that dissolves or disintegrates in the oral cavity without the need for water or chewing. More recently, fast-dissolving films are gaining interest as an alternative to fast-dissolving tablets to definitely eliminate patients’ fear of chocking and overcome patent impediments. In the present study, calculations for amount of drugs were determined, Rapid dissolving films containing GSH were prepared using solvent casting method. An aqueous solution of polymer was prepared in distilled water. For preparing the solution, polymer was soaked in water for some time (wherever required). This was followed by addition of GSH in the aqueous solution of the polymer. Now, plasticizer (PEG 400 and/or Glycerol), sweetening agent (Aspartame and/or Sucralose), citric acid and flavor were also added to this solution. In-vitro disintegration time (DT) of the prepared rapid dissolving films was determined visually in a glass beaker containing 50ml water and swirling every 10 seconds. Average of 3 films was taken for this purpose. In-vivo DT of the prepared rapid dissolving film was determined by mouth in three human volunteers. Evaluation of taste was done by a taste panel with 2mg drug and subsequently one film held in the mouth for 10-15 seconds. For preparing rapid dissolving films, varying amount of Pullulan, METHO K3P, METHO E3P were taken. Solvent evaporation method was used for preparation of the film. Various polymers used in the study were: Pullulan, Metho K3P, Metho E3P, Metho E15P and Poly N10. PEG-400 and glycerol were used as plasticizer. Aspartame and sucralose were used as sweetening agent while citric acid was used as saliva stimulating agent
Keywords: Rapid dissolving film, Ondansetron hydrochloride (OND), Granisetron Hydrochloride (GSH).
Propensity Score Analysis and Its Applications
Authors: Santosh Kumar Rada , Ramya M.
Published: September 2024

This review considers casual inference in observational studies which can prove medical treatment. The main aim of this study is to describe about its application in non-randomized clinical studies and in persons who support regulatory applications for marketing medical product. Propensity score makes an easy study about the large number of groups which cannot be randomized. By measuring the covariates, the methods which are used to measure the propensity score mimic the covariates. This study shows an illustration of the steps in the study and construction of propensity scores verses normal treatment of seriously ill individuals. Propensity score has the major advantage over alternate approaches when the treatment methods of illness do not overlap.
An Overview on Transdermal Drug Delivery System
Authors: Maurya Vijay Bahadur , Kumar Vinay , Kumar Rajeev
Published: September 2024

Transdermal drug delivery is involved in the transportation of drug through the skin for systemic circulation. Now a day’s more than 74% of drugs are administered drug in the form of tablet, capsule, which are taken orally but sometimes those are not effective as desired due to physiological activities of body. The major obstruction caused by stratum corneum to penetrate the drug. So there is need to facilitate the stratum corneum to increase the flux, a number of approaches are used to enhance the penetration of drug. Transdermal drug delivery system (TDDS) are very effectively overcome the hepatic first pass metabolism and improve the steady plasma drug concentration. The present review article provides an overview of various types of transedrmal patches, method of preparation and their evaluation.
Keywords- Transdermal drug delivery system, First pass metabolism, TDDS
Taste masking Technologies: A Boon for Oral Administration of Drugs
Authors: Santosh Kumar Rada , Sai Kiran A.
Published: September 2024

Oral administration is widely used route of administration of drugs. The drug travels from the mouth, into the esophagus, then into the intestines. Sensing the taste is the major function of the tongue. In the formulation for pediatric & geriatric, bedridden & non-Cooperative patients, the main challenge to compounding pharmacist is to mask the taste of obnoxious and bitter drugs, result in patient non-compliance. Patients now expect and demand formulations that are pleasantly, or at least tolerable, flavored. This article reviews on taste-masking technologies and approaches for taste masking and bitterness reduction of dosage forms. 
Keywords: Oral Administration, Drugs, Taste making, Taste bud
Nanosponges: Novel Drug Delivery for Treatment of cancer
Authors: Santosh Kumar Rada , Bhowmik Ankana
Published: September 2024

The problems faced due to the conventional drug delivery system have been defeated after the invention of nanosponges (NS). NSs drug delivery system is considered as the novel drug delivery system which has emerged as one of the most successful fields in life sciences. Nanosponges have been proved to be a boon in the treatment of cancer. Conventional drug delivery system, used in the treatment of cancer is generally insoluble and produces serious side effects. Thus, nanosponges are used in which the active drug is entrapped in a complex of polymers such as cyclodextrins. The drug is released from these nanoparticles to the specific targeted tumor sites and produce optimum therapeutic effect and minimal side effects. The nanosponges are generally biodegradable in nature. The solubility of the drug is increased due to which hydrophobic drugs can be incorporated within the NSs. The patient compliance is also improved due to this type of drug delivery system. Various factors which influence the drug delivery of NSs are the type of polymer used, type of drug incorporated, temperature, method of preparation and degree of substitution. The NSs are formulated by maintaining the above factors. The methods used are solvent method, melt technique, ultra-sound assisted synthesis, emulsion solvent diffusion method and loading the drug into the NSs. NSs are either crystalline or paracrystalline which have different loading capacities. This review mainly focuses on the nanosponges used as anticancer agents. The factors, method of formulation of the nanosponges are discussed in detail.
Keywords: Nanosponge, biodegradable, polymers, minimal side effects, targeted tumor sites.
Educação, história, memória e cultura: diversidade e decolonialidade em diferentes espaços sociais
Authors: Bressanin César Evangelista Fernandes , Almeida Maria Zeneide Carneiro Magalhães de
Published: September 2024

Os textos que compõe esta coletânea "Educação, História, Memória e Cultura: diversidade e decolonialidade em diferentes espaços sociais" resultaram dos trabalhos apresentados durante o III Colóquio Internacional do Diretório de Pesquisa “Educação, História, Memória e Cultura em diferentes espaços sociais” (EHMCES) da Pontifícia Universidade Católica de Goiás (PUC-GO), cadastrado junto ao CNPq (Conselho Nacional de Desenvolvimento Científico e Tecnológico) e vinculado à Rede de Pesquisa HISTEDBR (Grupo de Estudos e Pesquisas "História, Sociedade e Educação no Brasil”) da Universidade de Campinas, realizado nos dias 13 e 14 de novembro de 2023, no formato online, transmitido pela página do Youtube do Diretório (https://www.youtube.com/@diretorioegrupodepesquisae1399) e pela plataforma do Google Meet. Gratidão aos pesquisadores e pesquisadores, professores e professoras envolvidos nesta coletânea e que deixaram aqui um pouco de seus trabalhos, suas reflexões e suas contribuições para o mundo acadêmico, da pesquisa e das ciências humanas que são “desafiadas a propor caminhos viáveis às interrogações humanas” (Chizzotti, 2016, p. 1558) e, no tempo presente, em que o neoliberalismo opera a sua desvalorização (Costa, 2016) são “obrigadas a mobilizar toda força inventiva da inteligência e toda energia criadora da ação para reinventar, continuamente, a história, trazer fundadas esperanças e revelar caminhos viáveis para a realização da vida humana, perseguindo as vias científicas de validar suas descobertas inovadoras” (Chizzotti, 2016, p. 1558-1559). O Diretório de Pesquisa Educação, História, Memória e Cultura em diferentes espaços sociais /HISTEDBR /CAPES /PROPE /PUC-GO deseja que a leitura dos textos aqui apresentados seja frutífera: enriqueça o arcabouço intelectual, gere aprendizado, estimule a reflexão, contribua para outros estudos e outras pesquisas.
Educação, história, memória e cultura: diversidade e decolonialidade em diferentes espaços sociais
Authors: Bressanin César Evangelista Fernandes , Almeida Maria Zeneide Carneiro Magalhães de
Published: September 2024

Os textos que compõe esta coletânea "Educação, História, Memória e Cultura: diversidade e decolonialidade em diferentes espaços sociais, volume 2 " resultaram dos trabalhos apresentados durante o III Colóquio Internacional do Diretório de Pesquisa “Educação, História, Memória e Cultura em diferentes espaços sociais” (EHMCES) da Pontifícia Universidade Católica de Goiás (PUC-GO), cadastrado junto ao CNPq (Conselho Nacional de Desenvolvimento Científico e Tecnológico) e vinculado à Rede de Pesquisa HISTEDBR (Grupo de Estudos e Pesquisas "História, Sociedade e Educação no Brasil”) da Universidade de Campinas, realizado nos dias 13 e 14 de novembro de 2023, no formato online, transmitido pela página do Youtube do Diretório (https://www.youtube.com/@diretorioegrupodepesquisae1399) e pela plataforma do Google Meet. Gratidão aos pesquisadores e pesquisadores, professores e professoras envolvidos nesta coletânea e que deixaram aqui um pouco de seus trabalhos, suas reflexões e suas contribuições para o mundo acadêmico, da pesquisa e das ciências humanas que são “desafiadas a propor caminhos viáveis às interrogações humanas” (Chizzotti, 2016, p. 1558) e, no tempo presente, em que o neoliberalismo opera a sua desvalorização (Costa, 2016) são “obrigadas a mobilizar toda força inventiva da inteligência e toda energia criadora da ação para reinventar, continuamente, a história, trazer fundadas esperanças e revelar caminhos viáveis para a realização da vida humana, perseguindo as vias científicas de validar suas descobertas inovadoras” (Chizzotti, 2016, p. 1558-1559). O Diretório de Pesquisa Educação, História, Memória e Cultura em diferentes espaços sociais /HISTEDBR /CAPES /PROPE /PUC-GO deseja que a leitura dos textos aqui apresentados seja frutífera: enriqueça o arcabouço intelectual, gere aprendizado, estimule a reflexão, contribua para outros estudos e outras pesquisas.
Parranda a dos tiempos. La muerte lenta del matachín de Capitanejo
Authors: Lucco García María Pierina
Published: September 2024

Este artículo analiza cómo la parranda de matachines en Capitanejo, Santander, es transformada a partir de la incursión guerrillera y paramilitar de la década de 1990 e inicios de los años 2000. Se propone que actualmente se encuentra un simulacro de la fiesta verdadera. Esta investigación ha sido elaborada mediante observación participante y entrevistas semiestructuradas, a partir del trabajo de campo prolongado realizado en diciembre del 2014 y la participación ininterrumpida en las parrandas de matachines de Capitanejo durante los últimos once años. Concluyo que estas celebraciones se encuentran en un momento de crisis en el que pueden tomar dos rumbos contrapuestos: fundirse en semejanza con una fiesta de disfraces genérica, con lo cual perderían su sentido y por lo tanto correrían el riesgo de desaparecer, o recuperar su vocación de mundo al revés rompiendo la dependencia institucional. Este análisis aporta a los estudios de fiestas y carnavales de Colombia comprendiendo su profundidad en las dinámicas sociales del presente.
Family archives of the residents of the Luhansk Region
Authors: Lurie Vadim
Published: September 2024

The article is based on the materials from the family archives of residents of the Luhansk region, digitized as part of the project “Donbas: Family Photo Archive” during the expeditions of 2018–2019. The material (both amateur photographs and studio shots) predominantly dates back to the 1960–80-s, a time of flourishing amateur pho- tography, but chronologically it covers the entire 20th century, including pre-revolutionary photographs and also pictures from the 1990-s. The narrative composition of the photo archives is characterized; special attention is paid to the representation of family life chronicles and the preservation of memories of various significant events, such as weddings (civil registry office registration, newlyweds visiting memorials, wedding celebration participants dressing up, etc.), the birth of a child, the child’s life (in particular, starting school and graduation events), home celebrations of New Year’s Eve and family members’ birthdays, military service (in particular, taking the oath), participation in May Day and November 7th demonstrations, and finally, funerals. Besides, the archives contain photographs of family members, their friends, and relatives (such photographs were customarily given as mementos, as evidenced by inscriptions on the back): photography, in addition to capturing family scenes, had a communicative function. The author also describes a database created on the Daminion platform by himself, which provides the ability to tag uploaded media files and search by key-words. A list of keywords characterizing the subjects of the Donbas photo archive and the number of photographs tagged accordingly is provided.
Ergonymic myth of Hermes: to research the religious life of legal entities
Authors: Gromov Bogdan , Polyakov Ilya
Published: September 2024

The article is devoted to the latest forms of manifestation of religiosity in the city space. The study focuses on studying the micro-levels of religious life in urban ergonymy. By examining store signs, navigation maps, and goods on the shelves of chain stores using the names of the gods of Ancient Greece, the article sets the task of reconstructing a non-verbalized mythological narrative composed by ergonyms and product names. The religious life of urban space is understood as the practices of piety characteristic of ancient Greek religiosity: invocation and dedication. The specific mechanisms of cultural reproduction in Ancient Greece and Europe of the 21st century are reconstructed. Based on the distinction made, the myth-socializing function of modern education in the process of broadcasting the mythological narrative and reinterpreting the Olympic myth is described. The article refers to data on the religious life of legal entities. Based on an analysis of the frequency of mentioning the names of the Olympic gods in the unified register of legal entities, and a comparison of the names of the gods with the declared forms of economic activity, the Olympic myth of the 21st century — the “Ergonymic Myth of Hermes” — is reconstructed. The article assumes scaling up the research to the study of “chorographies” — materially embodied spaces of the sacred on the streets of modern cities. The study of chorographies is proposed as a new methodology for studying culture and human coexistence.
Innovación en la cultura organizacional. Un enfoque multidisciplinario en la era digital
Authors: Balderas Trejo Oscar Giovanni , Cabrejos Burga Raúl
Published: September 2024

En la era digital, las organizaciones enfrentan desafíos sin precedentes que exigen una transformación radical en su estructura y cultura. Este libro, Innovación en la cultura organizacional: Un enfoque multidisciplinario en la era digital, nace de la necesidad de explorar estas transformaciones desde diversas perspectivas, reconociendo que la innovación en la cultura organizacional ya no es solo un lujo, sino una necesidad imperante para la supervivencia y competitividad en el mundo actual.
En sus páginas, se encontrarán una serie de análisis y estudios que, desde diversas disciplinas, invitan a reflexionar acerca de cómo las organizaciones pueden adaptarse, cambiar y prosperar en un entorno dominado por la tecnología, la inteligencia artificial y la globalización. Los autores y colaboradores de esta obra nos brindan una visión integral y profunda de los factores que impulsan la innovación, desde las teorías más tradicionales hasta las más recientes propuestas que surgen en el ámbito académico y profesional.
Esta obra es resultado de un esfuerzo colectivo de expertos en áreas tales como la psicología, la administración, la tecnología y la educación, quienes, desde sus respectivas trincheras, han aportado valiosos conocimientos que se convergen en un enfoque multifacético. Es, sin duda, una herramienta fundamental para cualquier líder, académico o profesional interesado en comprender y aplicar los cambios necesarios para transformar la cultura de sus entidades en la era digital.
Entendendo a Educação: Desafios atuais, Docência e Tecnologia
Authors: Gomes Maria Stella Alves Lima
Published: September 2024

Resenha do livro Entendendo a Educação: desafios atuais, docência e tecnologias.
Audit committee characteristics and financial reporting quality: Evidence from the emerging market
Authors: Alqatamin Dana A. , Alqatamin Rateb Mohammad
Published: September 2024

This paper seeks to provide empirical evidence regarding the effect of audit committee (AC) characteristics on the financial reporting quality (FRQ) in the Jordanian context. The sample was selected from nonfinancial Jordanian companies during 2016 and 2023. This specified period permits for the study of tendencies and altertions throughout time (Callahan & Soileau, 2017). This study used panel regression analysis and the random effect method to achieve the study aim. The study found a positive and significant relationship between audit size, gender diversity, independence, number of audit meetings, and FRQ. The results could benefit some financial information users, such as investors, and regulators. This paper has the goal of informing interested parties in auditing and managers about the value of selecting the right members of the AC since they contribute to enhancing the FRQ. It also adds to the existing literature by providing empirical evidence regarding the effect of AC characteristics on FRQ. Therefore, our research advances our understanding of the intricate relationships between AC as a corporate governance tool and FRQ by elucidating the precise roles that different AC characteristics play in influencing the accuracy and reliance of financial reports.
From Xavier Lefèvre to Frédéric Berr: Clarinet instruction at the Paris Conservatory between 1795 and 1838.
Authors: Théo Couillez
Published: September 2024

Student Number
3258904

Supervisor
Bart van Oort

Title
From Xavier Lefèvre to Frédéric Berr: Clarinet instruction at the Paris Conservatory between 1795 and 1838.

Research Question
How to describe clarinet instruction at the Paris Conservatory between 1795 and 1838?

Summary

The Paris Conservatory was founded in 1795. Xavier Lefèvre (1763-1829) was one of the first clarinet professor to teach there, from 1795 to 1824. In 1802 he published an important clarinet tutor intended for study at the Conservatoire: Méthode de clarinette. Frédéric Berr (1794-1838) held the same position from 1832 to 1838. In 1836 he published a Méthode complète de clarinette and a Traité complet de la clarinette.
Thanks to these writings, it is possible nowadays to get an idea of the skills needed by a French clarinettist of the early 19th century to play the music of his time. The aim of this research is thus to describe the main aspects of performance practice during the chosen period. Many of these aspects are not limited to the clarinet. Consequently, other methods for singing or for other instruments related to the Conservatory, have been studied to provide a broader perspective of performance practice at that time.
As the first decades of the 19th century witnessed important developments in clarinet making and instrumental technique, it has been essential to discuss this point in this research. However the central aspect of this work is musical expression, the ultimate goal of a performance. Phrasing, the variety of articulation and dynamics appear as essential tools for the performer who wants to communicate with the audience.

Short biography

Théo Couillez is a French clarinetist. He studied in his native country where he received the bachelor degree at the Pôle Supérieur Paris Boulogne-Billancourt in 2017. Eager to discover another approach to interpretation, he decided in 2019 to study for the Master degree in historical clarinet with Eric Hoeprich at the Royal Conservatory in The Hague. (Netherlands). Passionate about the symphonic orchestra, he took part to several orchestral academies such as the Youth European Orchestra Hector Belioz led by François-Xavier Roth and the Collegium Vocal Gent Academy led by Philippe Herreweghe.
Subversive Climes: Exploring the role of exoticism in Les Indes Galantes
Authors: Bethany Shepherd
Published: September 2024

Name: Bethany Shepherd

Main Subject: Early Music Singing

Research Supervisor: Charles Toet

Title of Research: Subversive Climes: Exploring the role of exoticism in Les Indes Galantes

Research Question: What is the role of exoticism in Les Indes Galantes?

Summary of Results: Exoticism in Rameau’s opéra-ballet Les Indes Galantes has three primary functions. By setting the plots of the four independent entrées in real but geographically distant cultures, the librettist Louis Fuzelier was able to introduce new spectacles to the operatic stage, providing novelty for audiences jaded by the tradition of entertainment based on gods and mythology. This dramatic development in turn provided Rameau with the opportunity to manipulate and extend the musical conventions of the time in order to create a style of expression appropriate to depict these exotic characters and locales. A deeper understanding of the context in which Rameau and Fuzelier created this work was has further revealed that the libretto and Rameau’s musical depiction of the characters in Les Incas du Pérou and Les Sauvages reflect the practice in early Enlightenment literary and philosophical cirlces of idealising exotic cultures to criticise eighteenth century French society. These conclusions offer modern performers a wider range of interpretive options when approaching this work, allowing for a more nuanced performance which brings together the elements of drama, music, philosophy and entertainment in a cohesive manner.

Biography: Australian soprano Bethany Shepherd studied Classical Singing at the Queensland Conservatorium of Music, under renowned Wagnerian soprano Lisa Gasteen. After obtaining a Bachelor degree with distinction in Australia, Bethany moved to The Netherlands to undertake studies in Early Music at the Koninklijk Conservatorium. She is currently completing a Master of Early Music Singing, studying with Rita Dams, Jill Feldman, Peter Kooij, Michael Chance and Pascal Bertin.
One in Norway by One of Them: Vlogging for Classical Musicians
Authors: Ursula Skaug
Published: September 2024

The internet is a promising place for musicians; one can promote and perform music for free, with possibly endless reach. Especially online video and streaming are booming spaces with many opportunities. Online music videos are often either recordings of a live performance, or they are an "online performance" from a musician who acts as if they are part of a regular live concert with an audience. However, the practices of regular concerts and online video are very different in nature. Perhaps online video requires a different way of engaging with the musical material within the video format. What if classical musicians created videos that emphasized the more casual and chatty style of the online platforms?
Through an iterative process I researched how classical musicians can use the vlog-style format with classical music and music theatre. In these vlogs I draw inspiration from the book "Three in Norway by Two of Them" and combine it with music by Julius Röntgen and Edvard Grieg. From this process I drew some conclusions and came up with a process for other musicians to try out this video format.
Diminutions, Divisions, and Doubles in Viol Literature
Authors: Alex Baker
Published: September 2024

Diminutions, divisions, and doubles are essentially different words for the same practice in viol literature - ornamenting music by dividing notes into smaller notes. The practice varies in name based on its context: in Italian and Spanish music it is called diminution, in English music it is called division, and in dance movements from French suites it is called a double. The question then remains: why do these theoretically identical practices remain distinct in name? Are there other ways in which they differ?

This exposition argues that there are indeed other ways in which these different families of diminution-style ornaments differ, and for this purpose it examines texts and scores from each group. For diminutions, the focus was Silvestro Ganassi’s “Opera intitulata Fontegara” (1535) and Diego Ortiz’ “Trattado de Glossas” (1553); for divisions, Christopher Simpson’s “The Division Viol” (1659); and for doubles, Marin Marais books of “Pièces de viole” (1686-1725).

The first chapter is an explanation of the chronological history of these different practices, beginning with diminution during the Italian Renaissance, moving to England in the mid-17th century, and ending with Marais’ suites from the late-17th to early-18th centuries. The second chapter explains the contextual differences of each style (in which genre/musical setting it was applied). The third chapter explores stylistic elements that are unique to each style, and the fourth chapter discusses the implications this information has for the modern player of the viola da gamba.