bluuebunny/crossref_metadata_2025 huggingface dataset:
Diagnostic Performance of Kaiser Score for Characterization of Breast Lesions on Modified Abbreviated Breast MRI and Comparison with Full-Protocol Breast MRI
Authors: Erkan Merve , Ozcan Seray Gizem Gur
Published: January 2025

Background: This study aimed to evaluate the diagnostic performance of the Kaiser score (KS) on the modified abbreviated breast magnetic resonance imaging (AB-MRI) protocol for characterizing breast lesions by comparing it with full-protocol MRI (FP-MRI), using the histological data as the reference standard. Methods: Breast MRIs detecting histologically verified contrast-enhancing breast lesions were evaluated retrospectively. A modified AB-MRI protocol was created from the standard FP-MRI, which comprised axial fat-suppressed T2-weighted imaging (T2WI), pre-contrast T1-weighted imaging (T1WI), and first, second, and fourth post-contrast phases. Two radiologists reviewed both protocols, recording the KS for each detected lesion. Sensitivity, specificity, and positive and negative predictive values, as well as accuracy, were calculated for each protocol. Receiver operating characteristic (ROC) analysis was performed to determine the diagnostic performance of the modified AB-MRI compared to the FP-MRI. Results: In total, 154 patients with 158 histopathologically proven lesions (107 malignant, 51 benign) were included. For the diagnostic performance of the KS for modified AB-MRI and FP-MRI, the sensitivity was 96.3% vs. 98.1%, the specificity was 78.4% vs. 74.5%, PPV was 90.4% vs. 89%, NPV was 90.9% vs. 95%, and the diagnostic accuracy was 90.5% vs. 90.5%. The area under the curve (AUC) obtained from the ROC curve analysis was 0.873 and 0.863 for modified AB-MRI and FP-MRI for reader 1, respectively, and 0.859 and 0.878 for modified AB-MRI and FP-MRI for reader 2, respectively, (p < 0.001). Conclusions: Our modified AB-MRI protocol revealed comparable results in terms of the diagnostic value of the KS in characterizing breast lesions compared to FP-MRI and reduced both scanning and interpretation time.
Outcomes of a Structured Olfactory and Gustatory Rehabilitation Program in Children with Post-COVID-19 Smell and Taste Disturbances
Authors: Almalki Smai Khalid , Azzam Ahmed Mohamed , Alhammad Saad A. , Alabdulwahab Sami , Alshamrani Ahmed Ali , Alotaibi Abdulmajeed Nasser
Published: January 2025

Background/Objectives: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is closely related to SARS-CoV and uses angiotensin-converting enzyme 2 as its cellular receptor. In early 2020, reports emerged linking CoV disease 2019 (COVID-19) to olfactory and gustatory disturbances. These disturbances could be attributed to virus-induced damage to olfactory neurons or immune responses, thereby affecting sensory functions. This randomized controlled trial aimed to evaluate the effectiveness of a structured orofacial rehabilitation program in improving smell (olfaction) and taste (gustation) sensations in children post-COVID-19. Methods: Forty children recovering from COVID-19 in government hospitals in Saudi Arabia were included and randomly assigned to the control group or the experimental group. The orofacial program included (a) facilitation of olfactory function using the 40-item modified Arabic version of the University of Pennsylvania Smell Identification Test (UPSIT); (b) assessment of gustatory function using taste strips with four varying concentrations; and (c) orofacial myofunctional therapy. The intervention was applied three times a week and lasted for 3 months. Results: The experimental group showed a significantly greater improvement in UPSIT scores (median change of 24.1%) than the control group (14.7%; p = 0.010). However, no significant difference was found in the taste strip test scores among the groups or between male and female participants. Conclusions: This study suggests that a structured orofacial rehabilitation program could enhance olfactory and gustatory functions in children recovering from COVID-19.
Clinical Outcomes of Cardiac Transplantation in Heart Failure Patients with Previous Mechanical Cardiocirculatory Support
Authors: D’Alonzo Michele , Terzi Amedeo , Baudo Massimo , Ronzoni Mauro , Uricchio Nicola , Muneretto Claudio , Di Bacco Lorenzo
Published: January 2025

Objectives: Heart failure (HF) remains a significant public health issue, with heart transplantation (HT) being the gold standard treatment for end-stage HF. The increasing use of mechanical circulatory support, particularly left ventricular assist devices (LVADs), as a bridge to transplant (BTT), presents new perspectives for increasingly complex clinical scenarios. This study aimed to compare long-term clinical outcomes in patients in heart failure with reduced ejection fraction (HFrEF) receiving an LVAD as BTT to those undergoing direct-to-transplant (DTT) without mechanical support, focusing on survival and post-transplant complications. Methods: A retrospective, single-center study included 105 patients who underwent HT from 2010. Patients were divided into two groups: BTT (n = 28) and DTT (n = 77). Primary endpoints included overall survival at 1 and 7 years post-HT. Secondary outcomes involved late complications, including organ rejection, renal failure, cardiac allograft vasculopathy (CAV), and cerebrovascular events. Results: At HT, the use of LVADs results in longer cardiopulmonary bypass and cross-clamping times in the BTT group; nevertheless, surgical complexity does not affect 30-day mortality. Survival at 1 year was 89.3% for BTT and 85.7% for DTT (p = 0.745), while at 7 years, it was 80.8% and 77.1%, respectively (p = 0.840). No significant differences were observed in the incidence of major complications, including permanent dialysis, organ rejection, and CAV. However, a higher incidence of cerebrovascular events was noted in the BTT group (10.7% vs. 2.6%). Conclusions: LVAD use as BTT does not negatively impact early post-transplant survival compared to DTT. At long-term follow-up, clinical outcomes remained similar across groups, supporting LVADs as a viable option for bridging patients to transplant.
An Atypical Case of Rhabdomyolysis Following an Atypical Antidepressant Overdose
Authors: Ungureanu Raluca , Dumitriu Ana-Maria , Cobilinschi Cristian , Ene Rǎzvan , Buiuc Mihaela , Grințescu Ioana Marina , Mirea Liliana
Published: January 2025

Background: Bupropion, an atypical antidepressant and smoking cessation aid, is known for its potential to cause seizures, cardiotoxicity and neurotoxicity in overdose scenarios. However, overdoses may present variably, and muscular and renal complications, such as rhabdomyolysis and acute kidney injury (AKI), can emerge in unexpected ways. Previous reports have shown that severe overdoses can lead to a spectrum of complications, but the precise mechanisms linking bupropion overdose with rhabdomyolysis remain poorly understood. Clinical presentation: This paper presents the management of a severe rhabdomyolysis case following deliberate ingestion of 4 g of immediate-release bupropion. The report highlights the unexpected presentation of bupropion overdose, including a lack of typical neurotoxic or muscular symptoms, and the subsequent involvement of multiple factors in the decision to initiate early renal replacement therapy, despite the absence of overt acute kidney injury (AKI). Conclusions: This case underscores the importance of individualized patient assessment and the challenges of managing rare and complex drug overdoses. Early intervention with renal replacement therapy, despite the absence of acute kidney injury, may be justified in cases of significant rhabdomyolysis and potential renal complications. Clinicians should maintain a high degree of suspicion for complications like rhabdomyolysis in overdose scenarios and consider early renal support in patients at risk of renal failure, even in the absence of overt kidney injury. The findings also point to the need for a more nuanced approach to diagnosing and treating bupropion overdose in critically ill patients.
Utility of Abdominal Radiographs After Posterior Spinal Fusion for Neuromuscular Scoliosis
Authors: Tetreault Tyler A. , Lai Rachel , Phan Tiffany N. , Illingworth Kenneth D. , Skaggs David L. , Wren Tishya A. L. , Andras Lindsay M.
Published: January 2025

Background/Objectives: Postoperative ileus, the temporary cessation of gastrointestinal motility leading to accumulation of fluid and gas in the bowel, is a common complication following posterior spine fusion (PSF) in patients with neuromuscular scoliosis (NMS). Abdominal radiographs (KUBs) are often ordered to differentiate between ileus and mechanical obstruction but expose patients to radiation, add cost, and may lead to unnecessary work up. The aim of this study was to determine how often KUBs led to a change in treatment after PSF in patients with NMS. Methods: A retrospective review was conducted of NMS patients with ≥2-year follow-up treated with PSF between January 2014 and December 2019 at a tertiary pediatric hospital. Results: Of the 133 patients (age 13.7, SD 2.6 years; preoperative curve magnitude 82.8, SD 23.0 degrees; follow-up 44.7, SD 15.4 months), 22.6% (30/133) underwent KUB imaging due to abdominal pain, distension, or delayed return of bowel function. In total, 93.3% (28/30) of the KUB imaging was consistent with ileus. One KUB study resulted in a gastroenterology consultation and bowel cleanout, and one raised concerns regarding possible pneumatosis of the colon, prompting a pediatric surgery consultation and exploratory laparotomy which was unremarkable. Conclusions: KUBs were performed in nearly 25% of NMS patients during the acute postoperative period, but rarely provided useful diagnostic information leading to changes in management. In the presence of postoperative abdominal distension, feeding intolerance, and delayed return of bowel function, we advocate for continuing conservative measures until bowel function returns, reserving abdominal radiographs for patients with a worsening exam despite bowel rest or additional causes for concern.
Neonatal Feeding Practices and SARS-CoV-2 Transmission in Neonates with Perinatal SARS-CoV-2 Exposure: A Systematic Review and Meta-Analysis
Authors: Babata Kikelomo , Sultana Rehena , Hascoët Jean-Michel , Albert Riya , Chan Christina , Mazzarella Kelly , Muhamed Tanaz , Yeo Kee Thai , Kong Juin Yee , Brion Luc P.
Published: January 2025

Background: The risk of neonatal SARS-CoV-2 infection from the mother’s own milk (MoM) in neonates who are exposed to maternal SARS-CoV-2 during the perinatal period remains unclear. We conducted a systematic review to assess the association between MoM feeding and neonatal SARS-CoV-2 infection in neonates who were born to SARS-CoV-2-positive pregnant persons. Methods: PubMed Central and Google Scholar were searched for studies published by 14 March 2024 that reported neonatal SARS-CoV-2 infection by feeding type. This search, including Scopus, was updated on 17 December 2024. The primary outcome was neonatal SARS-CoV-2 infection. The meta-analysis was conducted using a random effects model with two planned subgroup analyses: time of maternal PCR testing (at admission vs. previous 2 weeks) and dyad handling (isolation vs. some precautions vs. variable/NA). Results: The primary outcome was available in both arms of nine studies, including 5572 neonates who received MoM and 2215 who received no MoM. The GRADE rating was low quality, because the studies were observational (cohorts). The frequency of SARS-CoV-2 infection was similar in both arms (2.7% MoM vs. 2.2% no MoM), with a common risk ratio of 0.82 (95% confidence interval 0.44, 1.53, p = 0.54). No significant differences were observed in the subgroup analyses. Limitations include observational and incomplete data, other possible infection sources, small sample sizes for subgroup analyses, and neonates with more than one feeding type. Conclusions: Feeding MoM was not associated with an increased risk of neonatal SARS-CoV-2 infection among neonates who were born to mothers with perinatal infection. These data, along with reports showing a lack of active replicating SARS-CoV-2 virus in MoM, further support women with perinatal SARS-CoV-2 infection feeding MoM. Registration: PROSPERO ID CRD42021268576.
Open vs. Robot-Assisted Artificial Urinary Sphincter Implantation in Women with Stress Urinary Incontinence: A Multicenter Comparative Study
Authors: Dubois Alexandre , Capon Grégoire , Belas Olivier , Vidart Adrien , Manunta Andrea , Hascoet Juliette , Freton Lucas , Thibault Frederic , Cardot Vincent , Dubois Frédéric , Corbel Luc , Della Negra Emmanuel , Haab François , Peyrat Laurence , Cornu Jean-Nicolas , Grise Philippe , Descazeaud Aurélien , Fournier Georges , Peyronnet Benoit
Published: January 2025

Background: The artificial urinary sphincter has been an effective treatment for stress urinary incontinence caused by intrinsic sphincter deficiency in women. However, the use of this device has been limited by the technical difficulties and risks associated with the open implantation procedure. Preliminary studies using robotic techniques have shown promising results, but only one small study has compared robotic to open procedures. This study aims to compare the outcomes of robotic and open artificial urinary sphincter implantation in women with stress urinary incontinence due to intrinsic sphincter deficiency in a large multicenter cohort. Methods: Data were collected retrospectively from female patients who underwent open or robot-assisted artificial urinary sphincter implantation from 2006 to 2020 at 12 urology departments. The primary outcome was the rate of complications within 30 days after surgery, graded using the Clavien-Dindo Classification. Perioperative and functional outcomes were compared between the two groups. Results: A total of 135 patients were included, with 71 in the robotic group and 64 in the open group. The open group had a higher rate of intraoperative complications (27.4% vs. 12.7%; p = 0.03) and postoperative complications (46.8% vs. 15.5%; p < 0.0001). More patients in the robotic group achieved full continence (83.3% vs. 62.3%; p = 0.01). The open group had higher explantation (27.4% vs. 1.4%; p < 0.0001) and revision rates (17.5% vs. 5.6%; p = 0.02). The estimated 1-year explantation-free survival rate was higher in the robotic group. (98.6% vs. 78.3%; p = 0.001). Conclusions: Robot-assisted implantation may reduce perioperative morbidity and improve functional outcomes compared to open implantation in women with stress urinary incontinence.
Robotic Rectus Abdominis Myoperitoneal Flap for Posterior Vaginal Wall Reconstruction: Experience at a Single Institution
Authors: Iftekhar Noama , Cataldo Kathryn , Seo Seungwon Jong , Allen Brett , Giles Casey , Kelecy Matthew William , MacDavid Joshua , Baynosa Richard C.
Published: January 2025

Background: The adoption of robotic surgery has been widespread and increasing amongst gynecologic surgeons given the ability to decrease morbidity. It is important that plastic surgeons adjust their reconstructive algorithm to ascertain the benefits of robotic-assisted surgery. Herein we report our outcomes of robotic-assisted rectus abdominis muscle reconstruction of the posterior vaginal wall along with a current literature review on robotic-assisted reconstructive pelvic surgery. Methods: An IRB-approved retrospective review was completed of all patients who underwent robotic pelvic reconstruction between 2016 and 2024 at a single institution. Patients who underwent posterior vaginal wall reconstruction utilizing a robotic-assisted rectus abdominis muscle (RRAM) were selected for final analysis. Results: Thirty-two patients were identified who underwent pelvic reconstruction using robotic surgical techniques. Five (mean age = 56.2, 32–72; mean BMI = 30.0, 24–39.9) underwent posterior vaginal wall reconstruction with an RRAM flap. Two patients (40%) had minor wound complications, and one patient (20%) had vaginal stenosis eight years after operation. None had major complications requiring a return to the OR or hospital admission. All patients went on to achieve successful healing. Conclusions: In the literature, robotic-assisted surgery has shown significant advantages, including reduced morbidity with decreased intra-operative blood loss, reduced pain, faster recovery, and shorter hospital stays. The RRAM flap for pelvic reconstruction is well tolerated in patients despite comorbidities and preserves the minimally invasive benefits of extirpative surgery. As the technology becomes more widely incorporated, it is important for plastic surgeons to integrate robotic surgical techniques into their practice.
Cumulative Energy Demand Analysis of Commercial and Hybrid Metal-Composite Gears at Different End-of-Life Strategies
Authors: Borda Francesco , Adduci Rocco , Mundo Domenico , Gagliardi Francesco
Published: January 2025

Gears remain a fundamental component in mechanical power transmission, with ongoing research focused on enhancing performance and sustainability. This study addresses the process of gear lightweighting, a key factor for efficiency improvements in automotive and aerospace sectors. Traditionally, material removal from gear bodies results in weight reduction, but at the cost of increased noise and vibration. A novel approach using hybrid gears, which combine a metal rim and hub with a composite material web, offers a promising solution. This research proposes a comparative environmental analysis among a conventional full steel, a lightweight and a hybrid gear using a life cycle energy quantification. The study considers two End-of-Life (EoL) scenarios: a conventional open loop scenario with partial recycling and a closed loop scenario with comprehensive recycling, including a thermal recycling for carbon fiber-reinforced plastics. The Cumulative Energy Demand (CED) has been conducted by applying a cradle-to-grave approach. The CED has been evaluated for each gear configuration quantifying the impact of each unit process involved in the production of the gear, from raw material extraction to product manufacturing and from use phase to different EoL scenarios. The cumulative results, performed preserving the same mechanical performance, indicate that the CED of the hybrid gear in the conventional open loop scenario is comparable to the one of the full gears, with an increase of 12.58%. In contrast, in the closed loop scenario, the hybrid gear exhibits substantial energy recovery benefits, with an overall CED difference of 7.50% compared to the lightweight gear and of 28.82% compared to the full gear. These results underline the potential of hybrid gears to improve efficiency, being able to achieve a 20% weight reduction with respect to the full gears, and to reduce environmental impact if effective recycling strategies were implemented.
A Collision Avoidance MAC Protocol with Power Control for Adaptive Clustering Underwater Sensor Networks
Authors: Xue Libin , Lei Hong , Zhu Rongxin
Published: January 2025

Underwater sensor networks (UWSNs) play a vital role in marine exploration and environmental monitoring. However, due to the characteristics of underwater acoustic channels such as high delay, low bandwidth, and energy limitation, the design of an underwater media access control (MAC) protocol has brought great challenges, and existing MAC protocol designs rarely consider the influence of channel interference factors in networking. Therefore, this paper proposes a collision avoidance MAC protocol for clustering underwater sensor networks. The protocol first classifies users by combining the channel characteristics of underwater nodes and the distance measurement between nodes. Then, based on the clustering network, according to the channel correlation distance measurement between nodes and the communication range of the cluster head (CH), the transmit power in clusters is controlled to reduce the lifetime of the network based on the cumulative reduction in node power consumption. Finally, the cluster structure in each cluster is used to schedule the transmission of member nodes in the cluster, and at the same time, the energy consumption of nodes is reduced while multi-node collision-free transmission is realized. The simulation results show that the throughput of the proposed adaptive power control clustering MAC protocol (APCC-MAC) is 26.5% and 19.5% higher than that of packet-level slot scheduling (PLSS) algorithm and Cluster-Based Spatial–Temporal Scheduling (CSS) algorithm, respectively, providing better communication performance and stability for clustered underwater acoustic networks.
On the Static Stability and Seakeeping Performance of a Submerged Floating Tunnel Module in Wet Tow
Authors: Lee Ikjae , Jin Chungkuk , Kim Sung-Jae , Kim Moohyun
Published: January 2025

A case study is conducted for a submerged floating tunnel module (SFTM) in wet tow conditions. Inspired by the successful wet tow operations of spar platforms, a wet tow scenario is examined where a tunnel module, floating horizontally with a half-diameter draft, is towed by tugboats using towlines. To evaluate the static stability of the SFTM during wet tow, numerical static offset tests are performed at varying tow speeds to determine the equivalent system stiffness. These static offset tests consider surge, sway, roll, and yaw motions. Statistical analyses are subsequently performed based on the encounter-frequency approximation with varying equivalent stiffnesses. The most probable extreme motion analysis for 3 h under sea state 4 (HS=2.44 m and TP=8.1 s) shows that the beam sea condition causes the largest heave (0.6 m), and the stern sea (30 deg.) leads to the largest yaw response (0.85 deg.), which is likely to cause an instantaneous decrease in towing stability.
Navigating the Dynamics: Modeling of Wave Propagation at Taiping Bay Port for Enhanced Design and Management
Authors: He Dachuan , Zhang Xi , Liu Yakun , Chen Zhi , Nie Xiangjun , Wang Ke
Published: January 2025

This study presents a systematic analysis of wave propagation dynamics at Taiping Bay Port in Dalian, characterized by its deep navigation channel, narrow port entrance, and complex bathymetric features. This study addresses the gap in numerical simulations for extra-large port areas using an integrated modeling approach. Specifically, this research advances our understanding of wave behaviors in harsh maritime environments through an innovative coupling of the parabolic mild slope (PMS) wave model with the phase-resolving Boussinesq wave (BW) model. The PMS model, validated against measured data, effectively computes the incident boundary conditions for the BW model, which in turn has been refined to enhance wave prediction accuracy and model stability through optimized boundary settings. Our findings elucidate the intricate wave patterns and transformations within the harbor, highlighting the significant impact of the deep navigation channel on wave attenuation. This work not only contributes to the theoretical modeling of wave dynamics but also offers practical insights for the design and management of similar complex port structures, potentially guiding future developments in coastal engineering.
PTT-Mediated Inhibition of Cancer Proliferation and Tumor Progression by DARPin-Coated Gold Nanoparticles
Authors: Proshkina Galina M. , Shramova Elena I. , Serova Ekaterina V. , Myachev Egor A. , Mirkasymov Aziz B. , Deyev Sergey M. , Kotlyar Alexander B.
Published: January 2025

Targeting HER2-positive cancer cells with precision therapies is a critical challenge in oncology. Here, we present a study on gold nanoparticles (AuNPs) conjugated with DARPin_9-29, a designed ankyrin repeat protein with high specificity and affinity for HER2 receptors. In this study, we investigate the therapeutic potential of AuNP-DARPin_9-29 conjugates, which was synthesized and characterized by us earlier, for photothermal therapy (PTT). By combining AuNP-DARPin treatment with visible light illumination, we show selective inhibition of HER2-positive cancer cell proliferation and tumor progression in a murine model. The results highlight the effectiveness of AuNP-DARPin in disrupting cancer cell viability and reducing tumor growth, providing a cost-effective and targeted approach for combating HER2-positive cancers.
Stroke-SCORE: Personalizing Acute Ischemic Stroke Treatment to Improve Patient Outcomes
Authors: Seetge Jessica , Cséke Balázs , Karádi Zsófia Nozomi , Bosnyák Edit , Szapáry László
Published: January 2025

Background/Objectives: Acute ischemic stroke (AIS) is a leading cause of disability and mortality worldwide. Despite advances in interventions such as thrombolysis (TL) and mechanical thrombectomy (MT), current treatment protocols remain largely standardized, focusing on general eligibility rather than individual patient characteristics. To address this gap, we introduce the Stroke-SCORE (Simplified Clinical Outcome Risk Evaluation), a predictive tool designed to personalize AIS management by providing data-driven, individualized recommendations to optimize treatment strategies and improve patient outcomes. Methods: The Stroke-SCORE was derived using retrospective data from 793 AIS patients admitted to the University of Pécs (February 2023–September 2024). Logistic regression analysis identified age, National Institutes of Health Stroke Scale (NIHSS) score at admission, and pre-morbid modified Rankin Scale (pre-mRS) score as key predictors of unfavorable outcomes at 90 days (defined as modified Rankin Scale [mRS] score > 2). Based on these predictors, a simplified risk score was developed to stratify patients into low-, moderate-, and high-risk groups, guiding treatment decisions on TL, MT, combination therapy (TL + MT), or standard care (SC). Internal validation was performed to assess the model’s predictive performance via receiver operating characteristic (ROC) analysis and isotonic regression calibration with bootstrapping. Results: The Stroke-SCORE was moderately positively correlated with a 90-day mRS score > 2 (odds ratio [OR] = 0.70, 95% confidence interval [CI]: 0.58–0.83, p < 0.001), with an area under the curve (AUC) of 0.86, a sensitivity and specificity of 79% and 81%, respectively, and an overall accuracy of 80%. Simulations indicated that personalized treatment guided by the Stroke-SCORE significantly reduced unfavorable outcomes. Conclusions: The Stroke-SCORE demonstrates strong predictive performance as a practical, data-driven approach for personalizing AIS treatment decisions. In the future, external, multicenter prospective validation is needed to confirm its applicability in real-world settings.
Analyzing Corporate Social Responsibility, CEO Gender, and Compensation Structure: Evidence from U.S. Firms
Authors: Chulkov Dmitriy , Kim Joungyeon
Published: January 2025

This article examines how CEO compensation structure and CEO gender were associated with corporate social responsibility (CSR) performance in U.S. firms in the period between 2003 and 2013. Building on prior research in economics, finance, accounting, and management, which suggests gender differences in commitment to CSR, this study provides empirical evidence that female CEOs were positively associated with higher CSR performance. The analysis further shows that a higher proportion of equity in CEO compensation was positively associated with CSR, whereas higher proportions of cash bonuses and long-term incentive plans were negatively associated with CSR. Notably, a higher proportion of a cash bonus in CEO compensation further reduced CSR in firms led by female CEOs. These findings offer valuable insights for firms seeking to design executive compensation packages that align CEO behavior with the firms’ CSR objectives. This study contributes to the growing body of literature on CSR by providing empirical evidence on the role of CEO gender and compensation structure.
Risk Assessment of Non-Point Source Pollution Based on the Minimum Cumulative Resistance Model: A Case Study of Shenyang, China
Authors: Wang Yongxin , Qiao Jianmin , Hu Yuanman , Zhang Qian , Han Xiulin , Li Chunlin
Published: January 2025

Urban non-point source (NPS) pollution is an important risk factor that leads to the deterioration of urban water quality, affects human health, and destroys the ecological balance of the water environment. Reasonable risk prevention and control of urban NPS pollution are conducive to reducing the cost of pollution management. Therefore, based on the theory of “source–sink” in landscape ecology, combined with the minimum cumulative resistance (MCR) model, this study considered the influence of geographic-environment factors in Shenyang’s built-up area on pollutants in the process of entering the water body under the action of surface runoff, and evaluated its risk. The results indicated that the highest pollution loads are generated by road surfaces. High-density residential zones and industrial zones are the main sources of urban NPS pollution. Impervious surface ratios and patch density were the dominant environmental factors affecting pollutant transport, with contributions of 56% and 40%, respectively. The minimum cumulative resistance to urban NPS pollution transport is significantly and positively correlated with the distance from water bodies and roads. Higher risk areas are mainly concentrated in the center of built-up areas and roads near the Hun River. Green spaces, business zones, public service zones, development zones, and educational zones demonstrate the highest average risk index values, exceeding 29. In contrast, preservation zones showed the lowest risk index (7.3). Compared with the traditional risk index method, the method proposed in this study could accurately estimate the risk of urban NPS pollution and provide a new reference for risk assessments of urban NPS pollution.
How Landscapes and History Shape Copper in Vineyard Soils: Example of Fruška Gora Region, Serbia
Authors: Andreeva Irina , Gabechaya Valeria , Morev Dmitriy , Samardžić Miljan , Galić Zoran , Yaroslavtsev Alexis
Published: January 2025

Vineyards are distinctive agroecosystems heavily influenced by local natural factors and traditional management practices, with significant implications for the quality and quantity of grape production. This study investigated the ecological impact of copper-containing fungicides on the accumulation and distribution of copper, manganese, chromium, and cobalt in the upper soil horizons of vineyards of varying ages in the Fruška Gora region, Serbia. The results indicated a marked difference in total copper content across vineyards, with the oldest vineyard exhibiting levels 6.9 times above the regulatory limit. Factor analysis delineated a strong correlation between copper accumulation and vineyard age while also highlighting the influence of landscape morphology on the spatial distribution of heavy metals. The findings suggest that copper accumulation is primarily related to agricultural practices, particularly the duration of fungicide application, while the distribution of other heavy metals is more closely associated with topographic features. The novelty of our research lies in the fact that we have shown that the assessment of copper accumulation in soil in vineyard ecosystems should take into account not only viticultural practices but also the history of land use and the landscape characteristics of the area.
Effect of Tooth Wear on the Technological Parameters of the Milling Process of Asphalt Concrete Layers
Authors: Petrescu Marius Gabriel , Dumitru Teodor , Laudacescu Eugen , Tănase Maria
Published: January 2025

This article discusses the findings of an experimental study designed to investigate the cutting forces encountered during the milling of asphalt pavement, considering the influence of cutter teeth wear. Experimental research was carried out for different values of wear, considered as a change in the shape of the active part of the tooth and a reduction in its height. The aspects studied continue the previous research of the authors regarding the study of cutting forces when milling asphalt pavement, using new milling teeth (without wear). Through this new study, the authors want to highlight how the phenomenon of wear influences the mechanical conditions of the chipping process and the efficiency of asphalt pavement processing. The experimental research was performed using an original stand, designed by the authors of the article, equipped with instruments for recording the values of the cutting force in the direction of advance. The experimental part is completed by the numerical modeling using the discrete element method (DEM). Research has shown that the increase in cutting forces is more pronounced at low advanced speed. Increasing the advanced speed leads to a reduction in differences between the cutting forces corresponding to the use or not of the milling tooth wear compensation. The study’s findings offer valuable insights into how milling parameters influence cutting forces, providing a basis for optimizing asphalt pavement milling processes.
Experiment and Simulation Study on the Crashworthiness of Markforged 3D-Printed Carbon/Kevlar Hybrid Continuous Fiber Composite Honeycomb Structures
Authors: Ju Jinlong , Yang Nana , Yu Lei , Zhang Zhe , Jiang Hongyong , Wu Wenhua , Ma Guolu
Published: January 2025

Fiber hybridization can effectively solve the localized brittle fracture problem of composite honeycomb, but the interaction between different fibers leads to a very complex failure mechanism. Hence, 3D-printed hybrid continuous fiber composite honeycombs with a combination of carbon and Kevlar fibers are designed to study the structural failure behaviors by the experiment and simulation method. The experimental samples, including Onyx, carbon, Kevlar, carbon/Kevlar, and Kevlar/carbon composites, are fabricated based on Markforged 3D printing technology, and the crushing tests are conducted to evaluate the failure behaviors. An equivalence finite element modeling method to replace the heterogeneous microstructure of hybrid composites is proposed to analyze the failure behaviors. Results indicate that carbon/Kevlar honeycomb exhibits the highest energy absorption and cost effectiveness, while CFRP honeycomb demonstrates the highest load-carrying capacity. It is found that carbon/Kevlar and Kevlar/carbon honeycombs have significant hybrid effects compared to single-fiber honeycombs, which also reveals the hybrid mechanisms between carbon and Kevlar fibers. Furthermore, the Onyx honeycomb, lacking long fibers, exhibits brittle collapse, whereas other honeycombs show ductile collapse due to the presence of Kevlar fibers. Combining the simulation studies, the damage evolution mechanisms of honeycombs, including fiber/matrix tension and compression, shear damage, interface damage, etc., are further revealed. This work provides valuable insights into the design and failure analysis of 3D-printed hybrid fiber composite honeycombs.
Modification and Aging Mechanism of Crumb Rubber Modified Asphalt Based on Molecular Dynamics Simulation
Authors: Li Jian , He Liang
Published: January 2025

Asphalt modified with treated waste tires has good environmental protection and application value. However, the nano-modification mechanism of crumb rubber (CR) with asphalt is still unclear. This research investigates the mechanism, aging, and interfacial interaction with the aggregate of CR modification asphalt (CRMA). The base asphalt and CRMA (original and aged) and two typical aggregate models were constructed. The accuracy of the model was verified through multiple indicators. The effects of CR and aging on the physical properties (density, compatibility, and diffusion coefficient), mechanical properties, component interaction behavior, and interfacial interactions with aggregates of CRMA were systematically analyzed. The results showed that the CR reduced the diffusion coefficient of asphalt by about 31%. The CR inhibited the movement of the components of asphalt (especially saturate and aromatic), which significantly improved the mechanical properties of asphalt. The compatibility between asphalt and CR significantly deteriorated after aging. The difference in the solubility parameter was about four times that before aging. It is instructive for the regeneration of CRMA. Aging led to a decrease in the shear modulus and Young’s modulus of both base asphalt and CRMA, which verified and quantified the adverse effects of aging on the mechanical properties. Comparing the two aggregates, CaCO3 had a greater adhesion with asphalt than SiO2. The difference ranged from 22.5% to 39.9%, which quantified the difference in the adhesion properties of acid base aggregates with asphalt. This study can provide theoretical guidance for the modification and application of CRMA.
The Effects of Chain Conformation and Nanostructure on the Dielectric Properties of Polymers
Authors: Mogbojuri Gabriel , Abtahi Shaghayegh , Hendeniya Nayanathara , Chang Boyce
Published: January 2025

The dielectric properties of polymers play a pivotal role in the development of advanced materials for energy storage, electronics, and insulation. This review comprehensively explores the critical relationship between polymer chain conformation, nanostructure, and dielectric properties, focusing on parameters such as dielectric constant, dielectric loss, and dielectric breakdown strength. It highlights how factors like chain rigidity, free volume, molecular alignment, and interfacial effects significantly influence dielectric performance. Special emphasis is placed on the impact of nanofillers, molecular weight, crystallinity, and multilayer structures in optimizing these properties. By synthesizing findings from recent experimental and theoretical studies, this review identifies strategies to enhance energy efficiency, reliability, and mechanical stability of polymer-based dielectrics. We also delve into techniques such as electrostatic force microscopy (EFM) and focused ion beam (FIB) milling for characterizing breakdown mechanisms, offering insights into molecular design for next-generation high-performance polymers. Despite considerable progress, critical challenges such as achieving an optimal balance between dielectric permittivity and breakdown strength, understanding nanoscale interfacial phenomena, and scaling these materials for industrial applications persist. These gaps can be addressed by systematic structure–property relations, advanced processing techniques, and environmental studies.
Design and Synthesis of Phthalocyanine-Sensitized Titanium Dioxide Photocatalysts: A Dual-Pathway Study
Authors: Shao Qi , Liu Jiaqi , Chen Qiwang , Yu Jing , Luo Zhongbao , Guan Rongqiang , Lin Zichen , Li Mingxuan , Li Yi , Liu Cong , Li Yan
Published: January 2025

Phthalocyanine-sensitized TiO2 significantly enhances photocatalytic performance, but the method of phthalocyanine immobilization also plays a crucial role in its performance. In order to investigate the effect of the binding strategy of phthalocyanine and TiO2 on photocatalytic performance, a dual-pathway study has been conducted. On the one hand, zinc-tetra (N-carbonylacrylic) aminephthalocyanine (Pc) was directly grafted onto the surface of Fe3O4@SiO2@TiO2 (FST). On the other hand, Pc was immobilized on a silane coupling agent ((3-aminopropyl) triethoxysilane) grafted onto the surface of the FST. Through photocatalytic experiments on the two types of composite materials synthesized, the results showed that the photocatalyst obtained by directly sensitizing Pc (FSTP) exhibited better performance on rhodamine B(RhB) removal than did the other photocatalyst using the silane coupling agent (FSTAP). Further mechanistic studies showed that directly sensitized FSTP exhibited more efficient photogenerated electron–hole pair separation, whereas FSTAP linked by a silane coupling agent created an additional transport distance that might greatly affect the photogenerated electron transport. Therefore, the dual-pathway research in this work provides new guidance for efficiently constructing phthalocyanine-sensitized TiO2 photocatalysts.
Herbal Waste from Filter-Tea Production as Eco-Friendly Ash for Sustainable Natural Rubber Composites
Authors: Lubura Stošić Jelena , Bera Oskar , Vukša Teodora , Balaban Dario , Vidović Senka , Gavarić Aleksandra , Ostojić Sanja B. , Simić Siniša
Published: January 2025

Herbal dust, a waste byproduct from filter-tea production, was annealed to form ash that can be incorporated into natural rubber as an eco-friendly filler. Three types of herbal dust ash (HDA), green tea, hibiscus, and lemon balm, were added at two different contents, 2.5 and 5 phr, into the rubber compound, while the content of carbon black, as a filler, was maintained at 50 phr in all samples. The impact of HDA type and content on the rheological and mechanical properties of rubber products was evaluated. Rheological analysis showed that HDA samples exhibited slightly lower maximum torque values (around 11.6 dNm) than ash-free samples (13.53 dNm), yet maintained vulcanization effectiveness with minimal impact on torque or cure rate metrics. Mechanical testing found that samples with 2.5 phr of lemon balm ash achieved comparable properties to samples without added ash, while samples with added hibiscus preserved crosslinking density and hardness. The addition of HDA led to decreases in tensile strength, elongation at break, and hardness values, with slight changes suggesting its applicability in similar industrial contexts. The findings highlight HDAs potential as a cost-effective, sustainable filler for rubber production, contributing to circular economy practices by repurposing significant amounts of tea waste into high-quality rubber materials.
Sustainable Materials and Structures Used in Pavement Engineering
Authors: Guo Fucheng , Cannone Falchetto Augusto , Zhou Bochao , Wang Wentong
Published: January 2025

Sustainable materials and structures have become widely used in asphalt pavements to mitigate the resource crisis and achieve carbon neutrality [...]
Effect of Depth of Cut and Number of Layers on the Surface Roughness and Surface Homogeneity After Milling of Al/CFRP Stacks
Authors: Doluk Elżbieta , Rudawska Anna , Legutko Stanisław
Published: January 2025

A multilayer structure is a type of construction consisting of outer layers and a core, which is mainly characterized by high strength and specific stiffness, as well as the ability to dampen vibration and sound. This structure combines the high strength of traditional materials (mainly metals) and composites. Currently, sandwich structures in any configurations (types of core) are one of the main directions of technology development and research. This paper evaluates the surface quality of II- and III-layer sandwich structures that are a combination of aluminum alloy and CFRP (Carbon Fiber-Reinforced Polymer) after the machining. The effect of depth of cut (ae) on the surface roughness of the II- and III-layer sandwich structures after the milling process was investigated. The surface homogeneity was also investigated. It was expressed by the IRa and IRz surface homogeneity indices formed from the Ra and Rz surface roughness parameters measured separately for each layer of the materials forming the sandwich structure. It was noted that the lowest surface roughness (Ra = 0.03 µm and Rz = 0.20 µm) was obtained after the milling of the II-layer sandwich structure using ae = 0.5 mm, while the highest was obtained for the III-layer structure and ae = 1.0 mm (Ra = 1.73 µm) and ae = 0.5 mm (Rz = 10.98 µm). The most homogeneous surfaces were observed after machining of the II-layer structure and using the depth of cut ae = 2.0 mm (IRa = 0.28 and IRz = 0.06), while the least homogeneous surfaces were obtained after milling of the III-layer structure and the depths of cut ae = 0.5 mm (IRa = 0.64) and ae = 2.0 mm (IRz = 0.78). The obtained results may be relevant to surface engineering and combining hybrid sandwich structures with other materials.
Exploring Water-Induced Helical Deformation Mechanism of 4D Printed Biomimetic Actuator for Narrow Lumen
Authors: Zhao Che , Duan Lei , Hua Hongliang , Zhang Jifeng
Published: January 2025

To address the issues of limited adaptability and low spatial utilization in traditional rigid actuators, a biomimetic actuator with water-induced helical deformation functionality was designed. This actuator is capable of adaptive gripping and retrieval of objects in a narrow lumen. A numerical model was established to analyze its helical deformation mechanism, and the helical deformation characteristics of the actuator were calculated under different structural parameters. Based on four-dimensional (4D) printing technology, which integrates three-dimensional printed structures with responsive materials, experimental samples of biomimetic actuators were fabricated by combining thermoplastic polyurethane fiber scaffolds with water-absorbing polyurethane rubbers. By comparing the simulation results with the experimental data, the numerical model was corrected, providing theoretical guidance for the structural optimization design of the actuator. The experiment shows that the biomimetic actuator can act as a gripper to capture a small target in a lumen less than 5 mm in diameter. This research provides a theoretical and technical foundation for the development of specialized actuators aimed at narrow spaces.
Magnetic Curves in Homothetic s-th Sasakian Manifolds
Authors: Güvenç Şaban , Özgür Cihan
Published: January 2025

We investigate normal magnetic curves in (2n+s)-dimensional homothetic s-th Sasakian manifolds as a generalization of S-manifolds. We show that a curve γ is a normal magnetic curve in a homothetic s-th Sasakian manifold if and only if its osculating order satisfies r≤3 and it belongs to a family of θi-slant helices. Additionally, we construct a homothetic s-th Sasakian manifold using generalized D-homothetic transformations and present the parametric equations of normal magnetic curves in this manifold.
Arouse-Net: Enhancing Glioblastoma Segmentation in Multi-Parametric MRI with a Custom 3D Convolutional Neural Network and Attention Mechanism
Authors: Li Haiyang , Qi Xiaozhi , Hu Ying , Zhang Jianwei
Published: January 2025

Glioblastoma, a highly aggressive brain tumor, is challenging to diagnose and treat due to its variable appearance and invasiveness. Traditional segmentation methods are often limited by inter-observer variability and the lack of annotated datasets. Addressing these challenges, this study introduces Arouse-Net, a 3D convolutional neural network that enhances feature extraction through dilated convolutions, improving tumor margin delineation. Our approach includes an attention mechanism to focus on edge features, essential for precise glioblastoma segmentation. The model’s performance is benchmarked against the state-of-the-art BRATS test dataset, demonstrating superior results with an over eight times faster processing speed. The integration of multi-modal MRI data and the novel evaluation protocol developed for this study offer a robust framework for medical image segmentation, particularly useful for clinical scenarios where annotated datasets are limited. The findings of this research not only advance the field of medical image analysis but also provide a foundation for future work in the development of automated segmentation tools for brain tumors.
Generalized Weak Contractions Involving a Pair of Auxiliary Functions via Locally Transitive Binary Relations and Applications to Boundary Value Problems
Authors: Eljaneid Nidal H. E. , Alshaban Esmail , Alatawi Adel , Ali Montaser Saudi , Alsharari Saud S. , Khan Faizan Ahmad
Published: January 2025

The intent of this paper was to investigate the fixed-point results under relation-theoretic generalized weak contractivity condition employing a pair of auxiliary functions ϕ and ψ verifying appropriate properties. In proving our outcomes, we observed that the partial-ordered relation (even, transitive relation) adopted by earlier authors can be weakened to the extent of a locally ϝ-transitive binary relation. The findings proved herewith generalize, extend, improve, and unify a number of existing outcomes. To validate of our findings, we offer a number of illustrative examples. Our outcomes assist us to figure out the existence and uniqueness of solutions to a boundary value problem.