bluuebunny/crossref_metadata_2025 huggingface dataset:
Penetrating keratoplasty in children under 3 years old with congenital corneal opacities
Authors:   Jakarta Eye Center, Jakarta 10430, Indonesia; Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo-Kirana Hospital, Jakarta 10430, Indonesia, Susiyanti Made , Manurung Florence M. ,   Jakarta Eye Center, Jakarta 10430, Indonesia
Published: December 2021

AIM: To evaluate the graft rejection and visual outcomes after penetrating keratoplasty (PK) in the presence of various congenital corneal opacities in children.
METHODS: In this retrospective cohort study, children who underwent PK were then followed for 5y. The patient's medical records were collected from June 2014 until June 2019 and analyzed in December 2019. All patients were children under three years old with congenital corneal opacities with or without microcornea who came to a pediatric ophthalmologist and underwent PK in Jakarta Eye Center (JEC). Beforehand, all children have participated in a thorough evaluation for PK. In the case of severe microcornea was not advised to undergo surgery. The visual outcomes and graft survival rate were described in percentages. The graft survival plot was presented with Kaplan-Meier, while the visual acuity was analyzed using the Wilcoxon signed ranks test.
RESULTS: Sixteen eyes from eleven patients (seven girls and four boys) underwent PK. The graft survival rate of the first 6, 12, and 18 mo later of keratoplasty was 100%, 83.3%, and 66.7%, respectively. The overall mean survival time is 22mo (standard error 2.419), and no significant difference between the patients underwent PK before and after 36mo of their age (P=0.52). The graft failure was 50%, and post-surgery complications included cataract 43.7%, band keratopathy 12.5%, and scleromalasia 6.25%. Wilcoxon test analysis of visual acuity post keratoplasty was not statistically significant (P=0.34), while overall showed 44% improvements of visual outcome for 5y of follow-up. With a good survival at one year up to 22mo (83.3%), the visual acuity could be achieved (63%), and showed improvements (44%) during follow-up.
CONCLUSION: The complications are frequent for pediatric PK. Thus, corneal surgery on infants requires careful case selection, adequate pre-operative evaluation, skilled surgery (optical correction), very close cooperation family–physician, intensive post-operation care, and amblyopia management in the future.
Formation of a Common Euro-atlantic Strategy of Georgia, Moldova, and Ukraine: Tasks, Problems, Prospects
Authors: Eremina Natalia V.
Published: December 2021

The task of joining the EU and NATO has been officially announced in Georgia, Moldova and Ukraine. Therefore, in this case, we cannot talk about the competition of several integration projects in these countries. Moreover, Eurasian integration, in which Russia actively participates, is viewed by them as a factor of expansion and expansion of Russian political and economic influence. This exacerbates disputes about the prospects for European integration not only in the political establishment of these countries, but also among ordinary citizens who will finance the European aspirations of national elites. Cooperation with the EU and NATO is seen as a tool to overcome the possible "temptation of Eurasian integration" and the military superiority of Russia and its partners. At the same time, the question remains open - whether this desire corresponds to the positions of citizens or is an elite project. The purpose of the article is to analyze the grounds for uniting the efforts of Georgia, Moldova, and Ukraine in promoting the idea of European integration and joining NATO, correlating them with the readiness of both the EU and NATO to admit the three post-Soviet countries into their ranks.
O Aporte de Algumas Tecnologias na Revisão de Conceitos de Física 1
Authors: Cristina Keli Maurina , Liao Tarliz
Published: December 2021

O artigo apresenta os aportes teóricos que nortearam uma proposta do uso de algumas tecnologias digitais (TD) em relação ao déficit de conhecimento em Física básica de alunos ingressantes nos cursos de Engenharia da Universidade Tecnológica Federal do Paraná. O índice de retenção nessa disciplina acarreta um problema denominado "bolsão", caracterizado por um número alto de estudantes que precisam refazer a disciplina e encontram-se em uma lista de espera. Assim, desenvolveu-se o curso (Re)visando Física, na plataforma Moodle, de modo a contemplar os principais conteúdos que compõe os conhecimentos prévios da disciplina à disciplina de Física 1. A formatação do curso pensada em um viés das tecnologias digitais, a contar do pressuposto da sabedoria digital, contou com os aportes do Conectivismo e dos princípios da Teoria Cognitiva de Aprendizagem Multimídia (TCAM) que são examinados detidamente e, associados por meio de mapas conceituais.Considerou-se, portanto, que o uso dessas teorias em sinergia oferece um embasamento teórico que possibilita ao professor maior segurança no desenvolvimento de seus recursos didáticos digitais.
Palavras-chave: Ensino de física. Educação tecnológica. Formação inicial de professores.
Horta Acadêmica e Ensino Superior a Distância: uma Experiência em um Polo Presencial no Rio de Janeiro
Authors: Pereira Mônica , Portugal Anderson dos Santos , Lacerda Fátima Kzam Damaceno de
Published: December 2021

Hortas em instituições de ensino se caracterizam como locais capazes de ampliar as relações interpessoais através da realização de atividades didáticas e de sociabilidade. Este potencial integrador pode vir a preencher lacunas relacionadas a dificuldade do estudante se adaptar às diferenças entre os ambientes físico e virtual no ensino superior a distância. Neste contexto, o objetivo deste trabalho é relatar a experiência de elaboração e manutenção de uma horta em um polo de apoio presencial situado no estado do Rio de Janeiro e que envolveu a participação das comunidades acadêmica e externa. Foram organizadas duas oficinas com 28 estudantes e nove tutores presenciais do curso de licenciatura em ciências biológicas. Utilizou-se questionários pré e pós atividade para coletar a opinião dos participantes sobre a ação proposta. Foi constatado que tanto os estudantes como os tutores presenciais vislumbraram a horta acadêmica como facilitadora do processo ensino-aprendizagem, embora 29% dos participantes tenham considerado difícil a sua implantação. Desta forma, a horta foi considerada uma experiência didática viável na EaD, promovendo espaços de práticas de ensino, pesquisa e extensão.
Palavras-chave: Educação a distância. Educação ambiental. Interdisciplinaridade. Mediação pedagógica.
Educação em Tempos de Pandemia: Desafios da Docência Remota na Educação de Jovens e Adultos
Authors: Kluthcovsky Patrí­cia Corrêa Wasilewski , Joucoski Emerson
Published: December 2021

Esse estudo buscou observar os impactos do ensino remoto na prática docente na educação de jovens e adultos, através do envio de um questionário on-line aos 121 docentes do Centro Estadual de Educação Básica para Jovens e Adultos, localizado em Curitiba - Paraná. Embora muitas pesquisas científicas apontem para os desafios já enfrentados por esses educadores como a evasão escolar, a heterogeneidade e a baixa autoestima dos educandos, pouco se sabe sobre a prática do ensino remoto em tempos de pandemia. Os resultados da pesquisa trouxeram à tona a necessidade de capacitações para os docentes quanto ao uso das tecnologias, a falta de subsídios materiais compatíveis para a execução do trabalho remoto e além disso as revelações dos docentes evidenciaram também as dificuldades encontradas pelos educandos quanto a ausência ou incompatibilidade de materiais para a execução das atividades e a falta de conhecimento em relação ao uso das tecnologias para fins pedagógicos, impactando diretamente no trabalho docente.

Palavras-chave: Educação de Jovens e Adultos. Ensino remoto. Educação a distância.
O Ensino Remoto Emergencial e o Ensino da Matemática: Percepção dos Estudantes e Professores de Matemática Durante a Pandemia do Novo Coronavírus na Cidade de Desterro-PB
Authors: Gonçalves Flavia De Souza Lima , Cunha Douglas da Silva
Published: December 2021

Com a crise sanitária causada pela COVID-19 diversas áreas no mundo foram modificadas. No cenário educacional não foi diferente, entre essas modificações, a necessidade do fechamento das instituições escolares de forma repentina, passando a exigir um novo modelo educacional, a partir de uma maior utilização das tecnologias e o cumprimento de medidas para a prevenção à disseminação do vírus. Nesse cenário, este estudo tem em sua gênese, a percepção dos estudantes e professores sobre o ensino da Matemática durante a pandemia do Novo Coronavírus. Foi baseado em uma abordagem quali-quantitativa, cujo método adotado foi o estudo de caso, a partir da análise de um questionário on-line respondido por 03 (três) professores de Matemática e 69 (sessenta e nove) estudantes, ambos do Ensino Médio da cidade de Desterro-PB, cujo objetivo principal foi apresentar a percepção dos professores de Matemática e dos estudantes do Ensino Médio da referida cidade sobre as aulas remotas de Matemática durante a pandemia. O trabalho teve como fundamentação teórica os estudos dos autores Costa (2020), Cordeiro (2020), Vercelli (2020), Garcia (2020), Motin (2020) entre outros. Os resultados da pesquisa apontam que o ensino remoto emergencial é um desafio para o ensino e aprendizagem, pois este surgiu de maneira inesperada para todos os envolvidos e, embora muitos estudos passaram a abordar esse tema, ainda estamos lhe dando com algo novo, que carece ser revisto e moldado para se tornar acessível a todos.
A Ótica de Futuros Professores de Matemática no Contexto da Educação a Distância sobre Modelagem Matemática
Authors: Oliveira Wellington
Published: December 2021

O texto evidencia compreensões sobre a Modelagem manifestadas por futuros professores de Matemática. A pesquisa se sustentou na seguinte interrogação: "O que expressam futuros professores de Matemática sobre a Modelagem, após uma experiência vivida com ela na EaD?". Foi desenvolvida uma experiência com futuros professores um curso de Licenciatura em Matemática e, metodologicamente, esse estudo de natureza qualitativa, descritivo e reflexivo, nos convida a refletir sobre compreensões sobre Modelagem favorecidas pela prática com ela, na Educação a Distância (EaD). Como alguns dos resultados, evidenciou-se que a dinâmica de formação com Modelagem foi considerada imersiva, contribuindo para a elaboração de saberes didático-profissionais. As reflexões "na prática" sobre "o que é" e "como" fazer Modelagem, além de revelar sobre a dinâmica se articula às compreensões manifestadas sobre (prática com) Modelagem, quando emergiram compreensões de natureza epistemológica e pedagógica. Em linhas gerais, a pesquisa indicou não apenas ações para o desenvolvimento de práticas com Modelagem na EaD, como também configuram objeto de reflexão sobre as experiências que ocorrem nesse contexto, apontando a prática com Modelagem distinta das experiências vividas. Essa emergência sugere mudanças de paradigmas sobre a prática na EaD, intencionando mudanças nas concepções dos formandos sobre o que é ensinar e aprender Matemática.
Palavras-chave: Educação matemática. Ensino de matemática. Formação docente.
Escrita Coletiva Digital: Conceitos, Características e Tecnologias
Authors: Maria Sandra Andrea Assumpção , Lorandi Alexandra , Behar Patricia Alejandra
Published: December 2021

A Escrita Coletiva Digital é uma prática que tem se expandido de forma significativa nos diferentes níveis de ensino e ambientes profissionais. Este estudo tem como objetivo apresentar os conceitos que definem esse tipo de escrita, identificar suas principais características e apontar algumas possibilidades tecnológicas que sustentam essa forma de produção textual. Em relação ao conceito, foram levantados termos correlatos considerados por diversos autores. As características identificadas evidenciaram as especificidades da Escrita Coletiva Digital e, por fim, os recursos tecnológicos apresentaram a gama de possibilidades disponíveis aos usuários interessados nessa prática.
Palavras-chave: Escrita coletiva digital. Recursos tecnológicos. Produção textual.
Competência Comunicativa Crítica no Ensino de Línguas a Distância: Reflexões e Propostas Preliminares a partir da Ideia de Brechas
Authors: Coelho Iandra Maria Weirich da Silva
Published: December 2021

Este artigo apresenta uma análise do material instrucional de um curso de língua espanhola, na modalidade a distância, em busca de indícios sobre seu potencial crítico e emancipatório. A discussão é realizada à luz do arcabouço teórico da Pedagogia Crítica e da Abordagem Comunicativa, com foco nas possibilidades de novas práticas pedagógicas que visam ao desenvolvimento da competência comunicativa crítica. Os procedimentos metodológicos adotados foram a pesquisa bibliográfica, de natureza qualitativa e análise das possiblidades de interação e desenvolvimento do senso crítico, a partir da ideia de brechas e problematizações das situações contextualizadas que emergem dos materiais e conteúdos. A discussão evidencia possiblidades do desenvolvimento do pensamento reflexivo, crítico e emancipatório, objetivando à diminuição de assimetrias e superação de visões e relações estereotipadas, em um contexto em que língua se caracteriza como um elemento-chave para alcançar o respeito à interculturalidade e à atuação do estudante como cidadão plurilíngue.
Palavras-chave: Educação a distância. Pedagogia crítica. Competência comunicativa crítica. Ensino de línguas.
Only seeing is believing – the power of evidence and reason
Authors: Rupp Bernhard
Published: December 2021

Biomolecular crystallography is a mature science that provides an instructive example for modern inductive reasoning as a model for Bayesian epistemology in empirical science. Fundamental scientific epistemology requires that a strong claim is supported by strong and convincing proof. Biomolecular crystallography, based on solid foundations of rich experimental data and extensive prior knowledge provides a prime example for modern, evidence based reasoning that strongly relies on assessments of plausibility based on prior knowledge while at the same time constantly delivering some of the most novel and exciting results based on new experimental evidence. As a consequence of the solid underlying physical principles and its mathematical rigor, crystallography as a mature science could be almost fool proof â were it not for the human element.
Structure-guided, target-based drug discovery – exploiting genome information from HIV to mycobacterial infections
Authors: Malhotra Sony , E. Thomas Sherine , Ochoa Montano Bernardo , L. Blundell Tom
Published: December 2021

The use of protein crystallography in structure-guided drug discovery allows identification of potential inhibitor-binding sites and optimisation of interactions of hits and lead compounds with a target protein. An early example of this approach was the use of the structure of HIV protease in designing AIDS antivirals. More recently, use of structure-guided design with fragment-based drug discovery, which reduces the size of screening libraries by decreasing complexity, has improved ligand efficiency in drug design. Here, we discuss the use of structure-guided target identification and lead optimisation using fragment-based approaches in the development of new antimicrobials for mycobacterial infections.
Sequence-specific endoribonucleases
Authors: Głów Dawid , Nowacka Martyna , Skowronek Krzysztof J. , Bujnicki Janusz M.
Published: December 2021

Ribonucleases are nucleolytic enzymes that commonly occur in living organisms and act by cleaving RNA molecules. These enzymes are involved in basic cellular processes,
including the RNA maturation that accompanies the formation of functional RNAs, as well as RNA degradation that enables removal of defective or dangerous molecules or ones that have already fulfilled their cellular functions. RNA degradation is also one of the main processes that determine the amount of transcripts in the cell and thus it makes an important element of the gene expression regulation system. Ribonucleases can catalyse reactions involving RNA molecules containing specific sequences, structures or sequences within a specific structure, they can also cut RNAs non-specifically. In this article, we discuss ribonucleases cleaving the phosphodiester bond inside RNA molecules within or close to particular sequences. We also present examples of protein engineering of ribonucleases towards the development of molecular tools for sequence-specific cleavage of RNA.
RNA 3’-terminal phosphate cyclases and cyclase-like proteins
Authors: Filipowicz Witold
Published: December 2021

RNA molecules bearing terminal 2’,3’-cyclic phosphate are quite common in nature. For example, 2’,3’-cyclic phosphate termini are produced during RNA cleavage by many en-doribonucleases either as intermediates or final products. Many RNA-based nucleases (ribo-zymes) also generate cyclic phosphate termini. However, cleavage reactions are not the only way in which RNAs bearing cyclic phosphate ends are produced. They can also be generated by RNA 3’-terminal phosphate cyclases (RtcA), a family of enzymes conserved in eukaryotes, bacteria, and archaea. These enzymes catalyze the ATP-dependent conversion of the 3’-phos-phate to a 2’,3’-cyclic phosphodiester at the end of RNA. In this article, I review knowledge about the biochemistry and structure of RNA 3’-phosphate cyclases and also proteins of the RNA cyclase-like (Rcl1) family, and discuss their documented or possible roles in different RNA metabolic reactions.
Structural insights into cell cycle control by essential GTPase Era
Authors: Ji Xinhua
Published: December 2021

Era (Escherichia coli Ras-like protein), essential for bacterial cell viability, is composed of an N-terminal GTPase domain and a C-terminal KH domain. In bacteria, it is required for the processing of 16S ribosomal RNA (rRNA) and maturation of 30S (small) ribosomal subunit. Era recognizes 10 nucleotides (1530GAUCACCUCC1539) near the 3â end of 16S rRNA and interacts with helix 45 (h45, nucleotides 1506-1529). GTP binding enables Era to bind RNA, RNA binding stimulates Eraâs GTP-hydrolyzing activity, and GTP hydrolysis releases Era from matured 30S ribosomal subunit. As such, Era controls cell growth rate via regulating the maturation of the 30S ribosomal subunit. Ribosomes manufacture proteins in all living organisms. The GAUCA sequence and h45 are highly conserved in all three kingdoms of life. Homologues of Era are present in eukaryotic cells. Hence, the mechanism of bacterial Era action also sheds light on the cell cycle control of eukaryotes.
Interactions of CCAAT/enhancer-binding protein β with transcriptional coregulators
Authors: Miller Maria
Published: December 2021

CCAAT/enhancer-binding proteins (C/EBPs) are key regulators of numerous cellular pro-cesses, including cell proliferation, differentiation, and tumorigenesis. Their biological activities require interactions with several protein partners and the formation of functional multiprotein complexes involved in DNA repair and cell cycle control. Members of the fam-ily (C/EBPα, β, δ, ε, and γ) bind to common DNA sequence motifs as homo- or hetero-dimers and interact with other transcription factors to control transcription of a number of eukary-otic genes. Of particular interest is C/EBPβ, which binds to closed chromatin and acts as a pioneering factor for initiating tissue-specific gene expression at several promoters. This review focuses on intermolecular interactions that underlie C/EBPβ’s ability to regulate chro-matin accessibility and directs readers to general reviews describing transcription regulation in eukaryotes.
Human β-defensin 4 – defensin without the “twist”
Authors: Prahl Adam , Pazgier Marzena , Alexandratos Jerry , Lubkowski Jacek
Published: December 2021

β-defensins are small, cysteine-rich, cationic peptides that contribute to various processes related to both arms of host defense, the innate and adaptive immunities. All β-defensins are potent antimicrobials with activity targeting a broad range of pathogens. Some human β-defensins (hBDs) are also capable of binding and activating specific chemokine receptors, leading to chemotaxis of receptor-presenting cells. Two receptors identified as targets of specific human β-defensins are CCR2 and CCR6, both members of the seven-transmembrane family of chemokine receptors. Currently, around 50 open reading frames (ORFs) identified in the human genome encode proteins that have signatures characteristic of β-defensins. Of those, only three, hBD1-3, have been thoroughly characterized to date, including a detailed structural description of their molecules. In addition, limited information on biological and bactericidal properties is available for hBD4, as well as the solution structure of hBD6. The crystal structure of hBD4, determined here at resolution of 1.60 Å, indicates significant structural differences between this molecule and those reported previously for other hBDs. Crystallographic studies indicate a possibility of unique dimerization of hBD4, confirmed by solution studies using analytical ultracentrifugation. In contrast to hBD1-3, hBD4 does not induce CCR6-mediated chemotaxis. This observation can be attributed to an unusual conformation of the hBD4 N-terminus. In agreement with previously published reports, hBD4 was shown to be a potent antibacterial agent, as demonstrated by results of assays with E. coli ATCC 25922 cells.
Perspective on SOD1 mediated toxicity in Amyotrophic Lateral Sclerosis
Authors: Sangwan Smriti , Eisenberg David S
Published: December 2021

A myotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive degeneration of spinal motor neurons. Although mutations in dozens of proteins have been associated with ALS, the enzyme, superoxide dismutase 1 (SOD1) was the first protein identified with the development of ALS and accounts for ~20% of familial cases. In experimental animals and patient samples, mutant SOD1 is found in cytoplasmic deposits implicating SOD1 aggregates as the toxic entities. Here we discuss the various biochemical and structure-based hypotheses proposed for mutant SOD1-associated ALS. Although much remains to be discovered about the molecular mechanism of SOD1 mediated toxicity, these hypotheses offer new avenues for therapeutic development.
Crystal pathologies in macromolecular crystallography
Authors: Dauter Zbigniew , Jaskólski Mariusz
Published: December 2021

Macromolecules, such as proteins or nucleic acids, form crystals with a large volume fraction of water, ~50% on average. Apart from typical physical defects and rather trivial poor quality problems, macromolecular crystals, as essentially any crystals, can also suffer from several kinds of pathologies, in which everything seems to be perfect, except that from the structural point of view the interpretation may be very difficult, sometimes even im-possible. A frequent nuisance is pseudosymmetry, or non-crystallographic symmetry (NCS), which is particularly nasty when it has translational character. Lattice-translocation defects, also called order-disorder twinning (OD-twinning), occur when molecules are packed regularly in layers but the layers are stacked (without rotation) in two (or more) discrete modes, with a unique translocation vector. Crystal twinning arises when twin domains have different orientations, incompatible with the symmetry of the crystal structure. There are also crystals in which the periodic (lattice) order is broken or absent altogether. When the strict short-range translational order from one unit cell to the next is lost but the long-range order is restored by a periodic modulation, we have a modulated crystal structure. In quasicrystals (not observed for macromolecules yet), the periodic order (in 3D space) is lost completely and the diffraction pattern (which is still discrete) cannot be even indexed using three hkl indices. In addition, there are other physical defects and phenomena (such as high mosaicity, diffraction anisotropy, diffuse scattering, etc.) which make diffraction data processing and structure solution difficult or even impossible.
Таможенные льготы в практике торгового сотрудничества стран ЕАЭС (на примере Республики Казахстан)
Authors: Михалина Е.Ю. , Ходакова А.Д. , Шаурина О.С.
Published: December 2021

Актуальность статьи подтверждается важностью обоснования целесообразности применения таможенных льгот, способствующих развитию международного торгового сотрудничества стран ЕАЭС. В научной статье определена практика, выявлены проблемы и обозначены возможные пути разрешения противоречий, возникающих в условиях реализации решений Казахстана в отношении поддержания и развития национального рынка сахара и продуктов, используемых при производстве продуктов с его применением. В современных международных турбулентных условиях формирование климата наилучшего благоприятствования для развития эффективных торговых взаимодействий стран-партнеров ЕАЭС предполагает поиск «точек опоры международного консенсуса», определения эффективных решений по включению торговых преференций в практику взаимного сотрудничества. В статье обозначены векторы реагирования и определены пути повышения эффекта применения таможенных льгот в целях развития международного сотрудничества.
Роль физической культуры в разрешении проблем здоровья человека
Authors: Славинский Н.В. , Служителев А.В. , Брянцева А.Р.
Published: December 2021

В данной статье показана динамика заболеваемости в XIX – XXI вв. В свою очередь, ежегодно растет потребность в привлечении широких слоев населения к занятию физической культурой для того, чтобы укреплять здоровье и проводить профилактику всевозможных заболеваний. Следует отметить, что структура заболеваемости указывает на необходимость не только совершенствования методов лечения различных болезней, но и на потребность еще более активного внедрения предохранительных мероприятий, в том числе и методик физической культуры, как основы здоровья людей в будущем. Важен не только теоретический, но и практический аспект данного вопроса. Исследуется научная литература по заданной проблеме, а также практический отечественный опыт.
Быт и нравы сортавальцев в XVII веке
Authors: Пашкова А.А.
Published: December 2021

Статья повествует о нравах и быте сортавальцев в первый век истории города - XVII век и проливает свет на ментальную проблему, которая является наименее изученной.
СПО ТОП 50 как шаг к усовершенствованию системы среднего профессионального образования
Authors: Бойкова А.В. , Баклушина И.В.
Published: December 2021

В данной статье поднята проблема дефицита рабочих специальностей и рассмотрены причины ее появления. Рассмотрен список ФГОС СПО по ТОП 50, который был создан для повышения престижа специальностей среднего звена. Обоснована востребованность данных направлений подготовки.
Православный художественный текст как средство воспитания религиозной толерантности на занятиях по русскому языку как иностранному
Authors: Букина Т.Г.
Published: December 2021

В статье описывается опыт преподавания русского языка как иностранного с позиций приобщения иностранных обучающихся к русской духовной культуре в целях воспитания в них религиозной толерантности. Работа основана на теоретическом и практическом материале, накопленном автором за период преподавания дисциплины в Уральском юридическом институте МВД России. В статье представлены рекомендуемые для изучения темы, а также описаны приемы работы с текстом из книги И.С. Шмелева «Лето Господне», который знакомит иностранных обучающихся с бытом и представлениями о духовности русской православной семьи рубежа XIX – XX веков. Данная повесть является ценным учебным материалом ввиду своего богатого духовного содержания, отражающего нравственные ценности русского национального сознания
Оценка функционального состояния студенток 1 курса по дисциплине «физическая культура и спорт» элективного направления «Фитнес» (опыт ПетрГУ)
Authors: Евтропкова Д.С.
Published: December 2021

В 2016-2017 в Петрозаводском Государственном Университете (ПетрГУ) была внедрена система организации учебного процесса по физическому воспитанию по элективным направлениям с учетом требований ФГОС ВО 3+. Предварительное анкетирование студентов 1 курса позволило определиться с предпочтениями обучающихся. Одним из популярных направлений студентами была выбрана элективная дисциплина «Фитнес» [3, с. 140]. В процессе работы по улучшению качества преподавания дисциплины, с использованием нестандартных и новых видов фитнес технологий, использовать данные результаты исследования показателей функциональных проб дыхательной и сердечнососудистой систем для повышения функционального состояния организма студенток. Результатом исследования стал анализ влияния занятий на функциональное состояние организма студенток 1 курса вуза по дисциплине «физическая культура и спорт» элективной дисциплины «Фитнес». Проводится анализ проведенных функциональных проб, занимающихся, осознанно выбранном направлении электива «Фитнес» и посвящена данная статья.
Технические средства обучения в преподавании иностранного языка обучающимся гуманитарного колледжа
Authors: Лопатина А.И. , Крепс Т.В.
Published: December 2021

В статье рассматриваются технические средства обучения, применяемы в преподавании дисциплины «Иностранный язык» обучающимся Гуманитарного колледжа КГУФКСТ. Анализируется, как с помощью информационных ресурсов, обучающиеся могут увеличить свой словарный запас в процессе чтения или прослушивания аутентичного лингвистического материала, а также совместной работе в процессе обсуждения и выполнения совместных заданий.
Прототипирование складного концентраторного теплофотоэлектрического солнечного модуля с двусторонним фотоприѐмником
Authors: Панченко В.А.
Published: December 2021

В статье предложена конструкция складного концентраторного теплофотоэлектрического солнечного модуля с двусторонним фотоприѐмником и произведено быстрое прототипирование разработанного модуля с помощью аддитивных технологий. Разработанный солнечный модуль позволит потребителям получать наряду с электрической энергией ещѐ и тепловую энергию в виде нагретого теплоносителя.
Современное состояние и перспективы развития электронных банковских услуг
Authors: Газиева Л.Р.
Published: December 2021

В статье описаны преимущества и недостатки удаленных сервисов, затронуты вопросы безопасности транзакций. Предлагаемый вариант повысит уровень безопасности для клиентов при переводе денег и проведении платежей через Интернет.
BIOSURFACTANTS FROM MARINE MICROORGANISMS: I. STRUCTURE AND FUNCTIONS
Authors: Galkin B. N. , Finogenova M. O. , Semenets А. S. , Galkin M. B. , Filipova T. O.
Published: December 2021

Marine microorganisms have unique metabolic and physiological characteristics and are an important source of new biomolecules such as biosurfactants. Low molecular weight surfactants are glycolipids, phospholipids, fatty acids, lipopeptides and lipoproteins, and high molecular weight surfactants are mixtures of heteropolysaccharides, lipopolysaccharides, lipoproteins and proteins. The main general of bacteria that synthesize biosurfactants are Pseudomonas, Bacillus, Acinetobacter, Antarctobacter, Rhodococcus, Halomonas, Alcanivorax, Pseudoalteromonas and Marinobacter. This review examines the structure and function of biosurfactants isolated from marine microorganisms.
BIOSURFACTANTS SYNTHESIS BY PSEUDOMONAS AERUGINOSA BACTERIA ISOLATED FROM THE SURFACE OF MUSSELS OF THE BLACK SEA
Authors: Finogenova M. O. , Galkin M. B. , Semenets A. S. , Prishchenko I. V. , Kaleva G. S. , Galkin B. M. , Metelitsyna I. P. , Filipova Т. О.
Published: December 2021

Aim. Establishing of the ability to synthesize surface-active compounds by Pseudomonas aeruginosa bacteria isolated from the surface of Black Sea mussels. Methods. During the research several marine Pseudomonas spp strains isolated from petroleum hydrocarbon contaminated areas of Black Sea wereused: P. aeruginosa M1, P. aeruginosa M4 and P. aeruginosa PA01 as reference strain in suspension and biofilm cultures (LB and Giss media). Cultivation of Pseudomonas aeruginosa strains was performed at 37 °C for 120 and 168 hours. Planktonic culture growth was determined spectrophotometrically on the wave length 600 nm. Biofilm mass was determined spectrophotometrically on the wave length 592 nm by CV-test. The presence of surface-active compounds was determined in a drop test. The quantitative content of rhamnolipids was evaluated by the color reaction of rhamnose with orcin. Results. P. aeruginosa strains M1 and M4 isolated from Black Sea mussel’s surfaces synthesize 25% and 66% more surfactants than the reference strain PA01. All strains in Giss medium synthesized 10–20 times less rhamnolipids than in LB medium. In biofilm cultures the same biosurfactant synthesis dependence on the composition of the nutrient medium is observed as in suspension cultures. According to the intensity of rhamnolipid production in biofilm cultures, the studied strains can be arranged in the following row: P. aeruginosa M4 > P. aeruginosa M1 >> P. aeruginosa PA01.Conclusions. The strains of P. aeruginosa isolated from the Black Sea are more efficient producers of rhamnolipids than the reference strain of P. aeruginosa PA01; the intensity of biosynthesis of surfactants significantly depends on the composition of the nutrient medium and the method of cultivation.
The Potential of Hydroxyapatite Toothpaste towards the Hypersensitive Tooth
Authors: Febriani Mirna , Amelia Herlin , Alawiyah Tuti , Rachmawati Emma
Published: December 2021

Dental hypersensitivity is a communal problem that we may often encounter in the daily life of both men and women, especially in the elderly who can unconsciously affect every daily activity. Dentin hypersensitivity is defined as sharp pain caused by stimulation of exposed dentin and unprotected dentin by enamel which can be caused by attrition, abrasion, crown fracture, gingival recession, and orthodontic trauma. Aim: The aim of this study was to analyse the potential of hydroxyapatite toothpaste towards the hypersensitive tooth through literature review. Method: This study analyzed 35 journals from each database PubMed, Ebsco, Google Scholar, ResearchGate, Wiley Online Library, and other international journal websites with keywords hydroxyapatite, hypersensitive dentin, remineralization. Conclusion: Toothpaste containing hydroxyapatite was more effective than toothpaste without hydroxyapatite in inducing tooth remineralization process. The use of toothpaste containing hydroxyapatite in the long term and routine for 15 days is more effective in reducing dental hypersensitivity.
«Автопортрет» и проблемы визуального в российской поэзии XX века
Authors: Малкина Виктория
Published: December 2021

В статье анализируется поэтика визуального в стихотворениях, озаглавленных «Авто- портрет». Визуальное при этом понимается как категория поэтики, предполагающая зри- мость внутреннего мира стихотворения для лирического субъекта и для читателя. Визуаль- ное в лирике может выражаться разными способами, в том числе и аллюзиями на жанры визуальных искусств, например, на автопортрет. Актуальность статьи заключается в выросшем в последнее время интересе к ин- термедиальности в литературе вообще и в лирике, в частности. Новизна работы состо- ит в рассмотрении поэтических автопортретов с точки зрения поэтики визуального. Ос- новная цель статьи – анализ способов визуальной репрезентации лирическим субъектом своего собственного образа. Затрагиваются следующие аспекты: взаимодействие лирики и живописи, общие и различные черты между живописным и лирическим автопортре- том; использование визуальных деталей; субъектная структура стихотворений и лири- ческий сюжет. Также делается попытка выстроить типологию автопортретов в лирике в зависимости от способов ви́дения лирическим субъектом себя: «Я» как взаимодействие «Я» и другого; «Я» как другой либо «Я» с точки зрения других. Материалом исследования послужили стихотворения А. Кушнера, И. Сельвинского, А. Вознесенского, О. Мандель- штама, К. Большакова, В. Катарсина, Н. Рыленкова, и др.
​SSR Based Genetic Diversity Analysis in Fenugreek (Trigonella foenum-graecum L.) Genotypes
Authors: Maloo S.R. , Sharma Radheshyam , Soan Himanshu
Published: December 2021

Background: Fenugreek (Trigonella foenum-graecum L.) is an important seed spice crop widely grown all over the world. In India, the state of Rajasthan is known for fenugreek production and productivity in the world. A concerted assessment of genetic variability among the germplasm accession is essential for breeding new superior varieties. Molecular markers such as AFLP, RAPD, ISSR, SSR, SCAR, SCoT, SRAP have become for the characterization of the germplasm rapidly and accurately. The present study aimed to characterize 20 elite fenugreek genotypes using simple sequence repeat (SSR) markers to assess the existing genetic diversity of this medicinal crop. Methods: The present study was carried out at the Rajasthan College of Agriculture, Maharana Pratap University of Agriculture and Technology, Udaipur, Rajasthan, India. Total genomic DNA was isolated from old leaves using the CTAB method (Doyle and Doyle, 1990). Further, PCR based genetic diversity was analyzed with using 50 SSR primer pairs. Dendrogram was constructed using NTSYSpc version 2.2 and clustering of the genotypes was done. Result: Twenty genotypes of fenugreek were assessed for genetic diversity analysis using SSR markers. Out of 50 markers 43 primer pairs produced 130 alleles with an average of 84.60% polymorphism. Jaccard’s similarity coefficient lied between and 0.39 to 0.82. Based on UPGMA clustering, a dendrogram consisting of five main clusters was generated with wide variability among the studied genotypes. These diverse genotypes so identified could be gainfully utilized in the fenugreek breeding programme.
UTILIZAÇÃO DE TECNOLOGIAS DIGITAIS NAS PRÁTICAS PEDAGÓGICAS NO CONTEXTO DA PANDEMIA DA COVID-19
Authors: Veras de Almeida Adrianne , Veras de Almeida Adrielle , De Oliveira Castro Maria Beatriz , De Lima Paulo Maria Amanda
Published: December 2021

Este trabalho teve como objetivo investigar as Tecnologias Digitais da Informação e Comunicação (TDICs) utilizadas pelos professores, bem como as dificuldades enfrentadas para a garantia da continuação do ensino-aprendizagem durante a pandemia da Covid- 19. Trata-se de um estudo de caso, cujos dados foram coletados por meio de um questionário on-line desenvolvido na plataforma Google Forms, sendo divulgado publicamente por alguns meios de comunicação, tais como: Instagram, Facebook, WhatsApp e e-mail. O período de coleta dos dados ocorreu entre os dias 6 de maio e 18 de junho de 2021, na qual se obtiveram 158 respostas. O questionário supracitado foi dividido em três seções, a saber: na primeira, continha o Termo de Consentimento Livre e Esclarecido (TCLE); na segunda, possuía seis questões referentes à atuação profissional (localização e profissão) do docente; e na terceira, a apresentação das 9 questões relacionadas ao uso de tecnologias digitais e  educacionais em sala de aula no período da pandemia, totalizando 15 questões com perguntas abertas, fechadas e de múltipla escolha, o que possibilitou, dessa forma, uma abordagem dos dados tanto em aspectos quantitativos como qualitativos. Os resultados obtidos indicaram que as principais dificuldades citadas foram a falta de capacitação e de um profissional da área de Licenciatura em Computação/Informática e, ainda, a adequação dessas tecnologias ao contexto das aulas remotas.
Palavras-chave: Educação. TDIC. Ensino remoto.
FUNÇÃO DO NÚCLEO DE ASSISTÊNCIA A PESSOAS COM NECESSIDADES ESPECÍFICAS EM CURSOS DE EDUCAÇÃO A DISTÂNCIA DO CAMPUS ZONA LESTE DO INSTITUTO FEDERAL DE EDUCAÇÃO, CIÊNCIA E TECNOLOGIA DO RIO GRANDE DO NORTE (IFRN)
Authors: Ferreira Cavalcante Ilane , De França da Silva Márcia , Das Chagas Lemos Elizama
Published: December 2021

Este trabalho faz uma revisão acerca das funções que o Núcleo de Assistência a pessoas com necessidades específicas (NAPNE) do Campus Zona Leste do Instituto Federal de Educação, Ciência e Tecnologia do Rio Grande do Norte (IFRN) vem desenvolvendo na assistência aos estudantes com deficiência desde a sua criação. O estudo apresenta o pioneirismo do IFRN em ações de assistência estudantil e seu desenvolvimento, ainda em processo, nas ofertas de cursos a distância. O Campus Zona Leste, anteriormente chamado Campi Educação a Distância, tem como principais ofertas cursos de Educação a Distância (EaD) de nível médio subsequente, licenciatura, tecnólogos, especialização e Formação Inicial e Continuada (FIC), voltados para a formação de professores e para a educação profissional. À luz de documentos e dados oficiais, o texto reflete sobre o conceito de inclusão e o NAPNE como instrumento nesse processo, com base em dados de matrícula de pessoas com deficiência no campus e considerando a EaD como uma possibilidade de ampliação de acesso à educação das pessoas com deficiência. O NAPNE do campus tem desenvolvido ações de apoio à permanência e ao êxito de estudantes com deficiência, tais como: oficinas, acompanhamento de estudos, suporte às práticas pedagógicas docentes e eventos de esclarecimento à comunidade.
Palavras-chave: Educação Inclusiva. Educação a Distância. Educação Profissional.
Flora of technologenic landscapes of the taiga zone of the European North-East (Komi Republic)
Authors:   Institute of Biology FRC Komi SC UB RAS, Martynenko V.A. , Gruzdev B.I.
Published: December 2021

The results of a long-term studu of the flora of technologenichabitats of the taiga zone of the Komi Republic are summarized. An annotated list of vascular plants is presented, including 406 species from 222 genera and 52 families. For each of them, it is indicated that they belong to a life from, an element of the flora and type of area, an ecologicsl group, zonal and ecotopic affinity. Data on the taxonomic composition of vascular plants, the biomorphrological, geographical, and ecological structures of synanthropic flora, the diversity of synanthropic plant communities, and the stages of vegetation restoration in disturbed areas are presented. The book is intended for botanists, ecologists, teachers of natural sciences, and students.
Study of the Ferromagnetic Magnetite Resonance (Fe3O4) Forms of Thin Films Using Micromagnetic Simulation
Authors: Salsabila Syefira , Rohman Lutfi , Purwandari Endhah
Published: December 2021

Fe3O4 is the strongest magnet among other iron oxides. Magnetite Fe3O4 is applied as a permanent magnet. The hysteresis curve of the permanent magnet Fe3O4 has a coercivity field that is not too large so that the material has a good chance to be applied as an absorbent material for RADAR waves. Micromagnetic simulations were carried out on Fe3O4 material in the form of thin film against hysteresis curves and ferromagnetic resonances at various thickness variations and side length variations, and the relationship was seen with changes in the bandwidth of the radar wave absorption frequency if the thickness variation of the simulated material had the same multiple as the experimental material. The thickness variations in this study were 60 nm, 90 nm, and 120 nm, where the variations in the experiment were 0.6 mm, 0.9 mm, and 1.2 mm. Micromagnetic simulation runs were performed to obtain the hysteresis curve and resonance frequency of the Fe3O4 material. The simulation results show that the resonant frequency increases with increasing thickness (fixed side length). Meanwhile, the relationship between the resonant frequency and the side length of the thin film is inversely related. Changes in the resonant frequency of Fe3O4 material are closely related to changes in the absorption frequency band of Fe3O4 material. The hysteresis curve obtained shows that the Fe3O4 material is a hard magnetic material. Changes in the resonant frequency of Fe3O4 material are closely related to changes in the absorption frequency band of Fe3O4 material. The hysteresis curve obtained shows that the Fe3O4 material is a hard magnetic material. Changes in the resonant frequency of Fe3O4 material are closely related to changes in the absorption frequency band of Fe3O4 material. The hysteresis curve obtained shows that the Fe3O4 material is a hard magnetic material.
Diagnostic features of intraarticular fractures of long tubular bones of the upper limb among children (literature review)
Authors: Myalin Victor N. , Gorelkin Dmitry O.
Published: December 2021

We present review of the works of domestic and foreign scientists published in publicly available electronic specialized medical journals devoted to the study of diagnosis issues on intraarticular fractures of long tubular bones of the upper limb among children. Traumatology, as well as medicine in general, is developing up to date, which leads to a significant expansion of diagnostic capabilities in traumatology practice. At the same time, the musculoskeletal system has many age-related features. The growth and development of the child’s body determine the specific course of various pathological processes and the great variability of their clinical manifestations. In this regard, there are clinical forms of intraarticular fractures of the long tubular bones of the upper limb characteristic of children, difficulties in recognizing which can still lead to diagnostic errors. This study examines the clinical manifestations of possible forms of intraarticular fractures of the long tubular bones of the upper limb in children, current methods of instrumental research, such as radiography, computed tomography, ultrasound, computer modeling and other methods that contribute to the correct diagnosis of these forms.
Quality of life assessment among children with psoriasis
Authors: Agafonova Yulia V. , Simonova Daria L. , Simonov Sergey N.
Published: December 2021

An increase of psoriasis in childhood, a more severe course of this disease, the presence of a cosmetic defect, which causes a negative impact on the quality of life of such patients, determine the relevance of this problem of modern dermatology. Psoriasis is characterized by a psoriatic rash, which is based on hyperkeratosis caused by uncontrollable mitosis of keratinocytes. Despite the recent studies of a large number of various mechanisms that can contribute to the psoriasis development, there is still no clear answer which of them is the main one, and this makes it impossible to achieve in most cases the desired clinical result of treatment, in particular, ensuring stable clinical remission or complete recovery of patients. The purpose of our study was to assess the impact of psoriatic manifestations on the quality of life among children. The object of observation was 106 children aged 4 to 17 years suffering from psoriasis. The average age of the children was 13 years. The measurement was carried out using the “Dermatological Quality of Life Index” (DLQI) (age 16–17 years), and the “Pediatric Dermatological Quality of Life Index” (CDLQI) (age 4–15 years). In addition, we analyze the severity indices of psoriasis in children: BSA, PASI and PGA. As a result of the study, the following was found: in general, psoriasis has a small impact on the quality of life in children – DLQI in children with psoriasis is 5 points; the value of the DLQI index is statistically significantly higher in girls than in boys, and with age the effect on the quality of life in children with psoriasis increases; skin lesions with psoriatic plaques of open areas in children has a significant impact on the quality of life: with scalp psoriasis, the DLQI level is the highest; statistically significant relationships between DLQI and psoriasis severity indices are established: between DLQI and BSA (r = 0.378; p < 0.001), between PASI and DLQI (r = 0.38; p < 0.001). With an increase in the intensity of manifestations of the pathological process assessed by the PGA index, the influence of psoriasis on the quality of life among children also increases (p = 0.011). According to the results of the study, methodological recommendations on medical and social support for children with psoriasis were drawn up and provided to specialized medical organizations.