bluuebunny/crossref_metadata_2025 huggingface dataset:
DESAFIOS E OPORTUNIDADES DO TELETRABALHO
Authors: Cardoso Josiane , Brum Argemiro , Vieira Euselia
Published: January 2025

Este estudo tem por objetivo analisar os desafios e as oportunidades do teletrabalho na percepção dos gestores em uma indústria alimentícia. Apesar da existência de pesquisas sobre os benefícios (Saura; Ribeiro-Soriano; Saldaña, 2022; Parent-Lamarche; Boulet, 2021) e os desafios do teletrabalho (Marchiori et al., 2020; De Vries; Tummers; Bekkers, 2019), observa-se uma lacuna na literatura a respeito da percepção dos gestores quanto aos desafios e às oportunidades dessa modalidade de trabalho. A maioria dos estudos se concentra na perspectiva dos colaboradores ou nos aspectos tecnológicos, negligenciando a visão estratégica dos gestores. A pesquisa foi realizada a partir de entrevistas semiestruturadas. A coleta de dados foi realizada com cinco gestores da Broker Nestlé, distribuidora exclusiva, atuante no segmento alimentício, situada na cidade de São José dos Campos – SP. Posteriormente, os dados foram analisados, utilizando-se a Análise de Conteúdo (Bardin, 2011), por meio da análise categorial. Os resultados aqui descritos, referidos na fala dos gestores de importantes e estratégicas áreas da empresa, corroboram com a literatura quando identificam o trabalho remoto como estratégia de atuação, que quando aplicada num contexto comercial, garante condições de produções estáveis e vantagem competitiva. Embora alguns pontos preocupantes tenham sido apontados pelos entrevistados como, isolamento social, jornadas de trabalho que precisam ser muito bem gerenciadas, evitando processos trabalhistas, de forma geral, as vantagens para os negócios e para a empresa, bem como, os desafios para os próprios gestores, foram reconhecidos pelos mesmos. Recomenda-se fazer estudos comparativos com outras empresas do mesmo setor para que seja possível identificar padrões e diferenças nas respostas ao uso desta modalidade de trabalho que tende cada vez mais aumentar.
Palavras-chave: teletrabalho; trabalho remoto; desempenho organizacional; percepção; gerência; indústria alimentícia.
Los semilleros escolares de investigación: un aporte a la calidad educativa
Authors: Ortega Herreta Andrea , Vergara de Alba Leydis
Published: January 2025

Los semilleros de investigación son la agrupación de jóvenes o niños que inician sus primeros pasos en el mundo de la investigación, estos jóvenes deben ser cuidados e incentivarlos, para que puedan ir desarrollando habilidades y destrezas. Durante este artículo de revisión, se revisaron aproximadamente 42 autores de investigación, quienes mencionan las variables estudiadas (calidad educativas y semillero de investigación), el enfoque metodológico de la investigación es cualitativo y el alcance es de tipo correlacional. Las bases de datos usadas para la búsqueda de los artículos fueron LEYES INFO, en la cual se indagaron los decretos y artículos de educación, Center for Educational Research and Innovation – CERI, todos los documentos de la OCDE, Google academic y science direct, para la búsqueda de artículos científicos y la UNESCO BIBLIOTECA DIGITAL, para todos los documentos de la UNESCO. Dentro de los resultados y discusión, se encuentran las comparaciones realizadas en primer lugar historia de la evolución del termino calidad educativa, luego trabajos que hablen de calidad educativa en las escuelas de manera internacional, nacional y local, seguido de las diferentes definiciones de semillero de investigación y los artículos encontrados con esta variable. Se concluye que las escuelas de básica y media, sí pueden mejorar sus procesos de calidad a través de semilleros investigativos.
Palabras Claves: Semillero de Investigación, Calidad educativa, escuela
Efecto de los Programas de Educación Económica y Financiera en la Educación Formal e Informal en Colombia
Authors: Valbuena Sonia , Palencia Rodolfo
Published: January 2025

La crisis económica mundial del año 2008, llevó al sistema financiero a una desaceleración económica mundial, la falta de conocimiento económico y financiero de ciudadanos y entidades contribuyó al mal manejo de esta crisis. Siendo desde entonces de gran importancia la necesidad de establecer lineamientos para formar al ciudadano a través de programas educativos que contribuyan a desarrollar habilidades financieras. Por tanto, es objetivo describir y analizar el efecto que han tenido en la educación formal e informal los programas de Educación Económica y Financiera (EEF) en el joven y el ciudadano en general. La metodología con enfoque cualitativo y una investigación de tipo descriptiva, basada en una revisión documental aplica a distintos documentos, estamentos e informes que presentan y evalúan los distintos programas con los cuales se ha implementado EEF en la educación formal e informal en Colombia. El resultado a resaltar es mayoritariamente una usencia de informes públicos de seguimiento, retroalimentación y ajustes a los programas de EEF. Se concluye la necesidad de procesos de evaluación y seguimiento del efecto que tienen los programas de EEF sobre el ciudadano en general que desde la educación formal e informal se implementan.
Semiosis del “Macho” en la Cultura del Carnaval
Authors: Martínez Martínez Olaris
Published: January 2025

El tema central de este artículo es la construcción simbólica y representación de la idea del “macho” cultural dentro de la esfera del carnaval.  Se pretende develar la significación y el tipo de transgresión que se concreta con la ritualización del cuerpo dentro del periodo de carnestolendas para presentar aportes a la teoría del carnaval desde la perspectiva antroposemiótica que conduzcan a una reflexión sobre la cultura y los discursos que se dinamizan en el carnaval. De esta manera, se hace un recorrido por los aportes de teorías sobre el carnaval elaboradas por varios autores y a partir de estos se amplía la discusión sobre la manera como la sociedad instituye la visión androcéntrica en la cultura del carnaval; se plantea la naturaleza del discurso de las pasiones y la ritualización del cuerpo desde la relación dual de Eros y Tánato, además de la objetivación de la transgresión en la condición cultural del “macho” ante la idea de virilidad.
Lean Management and Sustainable Development at Universities: Needs and the Possibilities of Implementation Within the Context of Strategic Provisions
Authors: Detyna Beata
Published: January 2025

Objective: The aim of this article is to evaluate how university strategies align with sustainable development principles and integrate Lean Management for continuous improvement. The main research problem was finding the answer to the question: to what extent do the provisions (strategic goals) contained in the university’s strategies relate to the concept of sustainable development and fit into the main idea of Lean Management, i.e. continuous improvement? The paper presents the partial results of the research project aimed at proposing a model for implementing Lean Management (LM) at a university and a self-assessment form of the effectiveness and efficiency of the methods and tools used by the university (as part of LM).Research Design & Methods: The research methods used were a combination of qualitative content analysis, comparative analysis, and literature review to explore the integration of sustainable development and Lean Management concepts within university strategies. The data sources were strategic plans, sustainability reports, and other relevant documents from the Monash University, the Warsaw School of Economics (SGH), and other institutions.Findings: Modern strategies of universities very often refer to the need to constantly adapt their offer (research, teaching) to contemporary social and economic needs. By balancing the development of universities, strategies and planned activities fit into the concept of sustainable local, regional, national, and global development. Therefore, it is important to recognise universities’ current needs and possibilities regarding implementing sustainable development as part of research carried out in the academic environment and to search for effective and efficient methods and tools that will serve it.Implications/Recommendations: The research advocates for universities to adapt strategies to meet contemporary societal needs, emphasising sustainable development and Lean Management principles. Addressing wastefulness and promoting continuous improvement encourages the integration of Lean Management into university strategies, aligning with sustainability goals and enhancing organisational efficiency.Contribution/Value Added: The article recognises universities’ current needs and the possibilities for implementing sustainable development and searching for adequate methods and tools for these challenges.Article classification: research articleJEL classification: I2
New Technologies in Crisis Management
Authors: Marciniak Dominika , Szymaniec-Mlicka Karolina , Kelm Hanna
Published: January 2025

Objective: Modern technologies are increasingly important in managing a public organisation. This also applies to the very sensitive area of crisis management, the effectiveness of which directly affects the health and lives of citizens. This article aims to analyse the literature on the subject of the use of modern technologies in crisis management.Research Design & Methods: The article uses literature review as a research method.Findings: The analysis of the obtained results indicates that the use of modern technologies in crisis management is a current research topic. At the same time, the application layer shows the potential of using modern technologies.Implications/Recommendations: Future research should focus on determining the acceptance of modern technology in the organisation. At the same time, it seems important to analyse the conditions for the optional implementation of modern solutions in the organisation.Article classification: theoretical/review paperJEL classification: H7
"EN PRENSA" Efecto del íTGBH sobre la calidad seminal de garañones “Cuarto de Milla” en la región de los Tuxtlas, Veracruz "EN PRENSA"
Authors: Hernández Beltrán Antonio
Published: January 2025

Con el objetivo de estudiar el efecto del clima a través del índice global del bulbo húmedo (íTGBH), sobre la calidad seminal de garañones Cuarto de Milla, en un criadero de los Tuxtlas, Veracruz, en ambiente tropical. Se evaluaron las variables meteorológicas temperatura ambiental y humedad relativa durante nueve años (2013-2021), para determinar el íTGBH diario y promedio mensual y relacionarlo con las características macroscópicas (volumen) y microscópicas (porcentaje de movilidad, vitalidad, espermatozoides normales y la concentración espermática) del semen obtenido de cinco sementales. Hubo un ambiente de confort térmico de diciembre a febrero (íTGBH≤26.99), dentro de la zona termo-neutral de los caballos; mientras que de abril a julio fue térmicamente estresante (íTGBH=32.99 a 36.80); con diferencia significativa (p≤0.05) en el porcentaje de movilidad (75.21±2.58 vs 62.79±2.51), vitalidad (80.50±2.03 vs 71.10±3.42) y espermatozoides normales (68.80±1.55 vs 58.02±2.0), siendo menor durante el periodo más caluroso. El volumen y concentración espermática no se vieron influenciadas por el aumento del índice pero sí por la estacionalidad. Se concluye que el incremento del calor, medido en términos de íTGBH tuvo un efecto negativo sobre la calidad seminal de los garañones.
Surveillance of SARS-CoV-2 and nosocomial infections causing agents in healthcare settings
Authors: Medrano Félix José Andrés , Lira Morales Juan Daniel , Gurrola López Valeria Lizbeth , Chaidez Quiroz Cristóbal , Martínez Rodríguez Célida Isabel , Castro del Campo Nohelia
Published: January 2025

SARS-CoV-2 has affected millions of people around the world and resulted in millions of hospitalizations, where it represents a potential source of nosocomial infections for medical staff and patients and the spread of the virus. This study focused on the detection of SARS-CoV-2 as well as Pseudomonas aeruginosa, Acinetobacter baumannii, and Staphylococcus aureus in healthcare settings, including intensive care unit, pediatric intensive care unit and COVID-19 care unit. The results showed that SARS-CoV-2 was present in surface samples from the COVID-19 care unit, which detected the presence of the Delta variant. Furthermore, results showed the presence of Pseudomonas aeruginosa and Staphylococcus aureus on hospital surfaces. The presence of SARS-CoV-2 and nosocomial bacteria highlights the importance of constant microbiological monitoring to prevent co-infections and the occurrence of nosocomial infections during hospitalization.
Сhanges of the functional phenotype of circulating monocytes during pregnancy
Authors: Bukhtueva N. G. , Leplina O. Yu. , Shevela E. Ya. , Tikhonova M. A. , Pasman N. M. , Ostanin A. A. , Chernykh E. R.
Published: January 2025

Rearrangement of the immune system during pregnancy is a strictly controlled, dynamic process in which the first and third trimesters are, respectively, pro-inflammatory, and anti-inflammatory periods. However, monocyte involvement in regulating the pro/anti-inflammatory balance remains poorly understood. The functional phenotype of monocytes is known to depend on their subsets assessed by CD14 and CD16 expression, and is associated with expression of M1(CCR2)- and M2(CD206) molecules, associated with pro- and anti-inflammatory activity, respectively. Here we have investigated the expression of CCR2 and CD206 in classical (CD14++CD16- , cMo), intermediate (CD14++CD16+, iMo), and non-classical monocytes (CD14+CD16++, nMo) in pregnant women at different gestational ages in comparison with nonpregnant women. The study included 14 pregnant women in the first trimester, 20 in the second trimester, 26 in the third trimester, and 29 fertile non-pregnant women. One-way analysis of variance in these groups revealed significant differences CCR2 and CD206 expression (more pronounced in classical and intermediate monocytes and stronger in relation to CD206 expression). Overall, monocytes from pregnant women had decreased CCR2- and increased CD206 expression, suggesting a shift towards an anti-inflammatory profile. These changes appeared in the first trimester (increased CD206 mean fluorescence intensity [MFI] in cMo and iMo, p < 0.05) and reached their maximum in the second trimester, manifested by significant increase in CD206 and decrease in CCR2 expression (% of cells, MFI) in all monocyte subsets. In the third trimester, CD206+ cMo decreased, as compared to the second trimester (p < 0.05), and the percentage of CCR2+ cMo and iMo increased. Of note, these changes in the first and third trimesters were combined with increased pro-inflammatory expression profile of non-classical monocytes which was restricted by the non-classical monocyte subpopulation in the first trimester, then being mediated by intermediate and non-classical monocytes in the third trimester. The data obtained suggest involvement of monocytes in regulation of the pro- and anti-inflammatory balance during pregnancy, with predominant development of the M2 profile in classical monocytes during the first and third trimesters, and in all monocyte subsets over second trimester, along with increase in the M1 proinflammatory profile of intermediate and non-classical monocytes in the first and third trimesters.
Systemic regulatory factors of angiogenesis in multiple uterine myoma
Authors: Konenkov V. I. , Shevchenko A. V. , Prokofiev V. F. , Koroleva E. G. , Timofeeva Yu. S. , Aidagulova S. V. , Marinkin I. O.
Published: January 2025

Uterine leiomyomas (UL) are benign uterine tumors. Hypertrophic increase in muscle mass in LM is accompanied by development of vascular networks, which are regulated by the balance of pro-angiogenic factors, e.g., VEGF-A. Moreover, a number of inflammatory molecules exert pro-angiogenic effects, especially, IL-1β, IL-8, etc. The spectrum of their activity may overlap, being regulated by other cytokines. The aim of our work was to assess serum concentrations of cytokines actively involved in vascular network growth in the patients with multiple uterine fibroids, as compared with data obtained in conditionally healthy women. The survey included 178 females: 89 women (23-60 years old) with uterine fibroids, and 89 conditionally healthy age-matched women (22-61 years old). The levels of TNFα, IL-1β, IL-4, IL-6, IL-8, IL-10 and VEGF-A were detected by ELISA technique (Vector-Best, Russia). Statistical analysis was carried out using the IBM SPSS Statistics 23 (USA). Serum levels of IL-6, TNF and IL-8, were higher among patients compared with healthy women. The dependence of VEGF level on the number of myoma nodes has been established: VEGF serum level was higher in patients with multiple tumor nodes. In healthy women, an increase in TNFα level showed direct correlation with higher serum level of IL-6. Correlation with VEGF level was weakly negative. In leiomyoma, these relationships persist for IL-6, IL-8, VEGF levels. The obtained data are of practical importance not only as potential prognostic criteria for development of the uterine myoma at preclinical stage, but also as additional laboratory indexes for differential diagnostics, in particular when discerning uterine leiomyoma, the most common benign myomatous tumor of uterus, from malignant uterine leiomyosarcomas.
The role of sensitization to birch polen allergens in the development of acute atopic dermatitis in patients living in Moscow and the Moscow region
Authors: Elisyutina O. G. , Smolnikov E. V. , Litovkina A. O. , Chernuchevich D. D. , Fedenko E. S.
Published: January 2025

Atopic dermatitis (AD) is a chronic inflammatory skin disease, its pathogenesis is associated with immunological disorders and genetically determined defects of the epidermal barrier. Exposure to aeroallergens, including pollen, plays a crucial role in the exacerbations and progression of AD. When individuals sensitized to pollen allergens come into contact with these allergens, a T2 immune response is activated, characterized by the release of cytokines IL-4, IL-13, and IL-31, which stimulate the production of IgE. This leads to enhanced inflammation, improved penetration of allergens through the compromised epidermal barrier, and activation of keratinocytes and dendritic cells, further impairing the skin barrier function and exacerbating AD symptoms. Previous studies have shown that pollen allergens can directly affect the epidermal barrier by activating proteolytic enzymes that break down intercellular connections in the epidermis, increasing its permeability to allergens and pathogens. This study analyzes the impact of sensitization to birch pollen allergens on the AD exacerbation in adult patients living in Moscow and the Moscow region. Birch pollen is a significant allergen capable of triggering exacerbations of allergic diseases, especially in the Northern Hemisphere countries where birch is widely spread. The study included 30 adult AD patients sensitized to birch pollen, and the SCORAD index was used to assess the severity of the disease, combining both objective skin condition indicators and subjective patient complaints (itching, sleep disturbance). Allergological examination was conducted using the ISAC ImmunoCAP allergochip, allowing for the determination of specific IgE levels to more than 100 allergens, including the main birch pollen allergen – Bet v 1. The analysis showed that most patients experienced a significant increase in AD symptoms during the birch flowering period, correlating with the levels of specific IgE to Bet v 1. The study highlights the clinical significance of sensitization to birch pollen as a trigger factor for AD exacerbation, confirming the need to analyze sensitization to pollen allergens to develop personalized approaches to the diagnosis and treatment of AD patients.
Early warning system using primary health care data in the post-COVID-19 pandemic era: Brazil nationwide case-study
Authors: Cerqueira-Silva Thiago , Oliveira Juliane F. , Oliveira Vinicius de Araújo , Florentino Pilar Tavares Veras , Sironi Alberto , Penna Gerson O. , Ramos Pablo Ivan Pereira , Boaventura Viviane S. , Barral-Netto Manoel , Marcilio Izabel
Published: January 2025

Abstract: Syndromic surveillance using primary health care (PHC) data is a valuable tool for early outbreak detection, as demonstrated by the potential to identify COVID-19 outbreaks. However, the potential of such an early warning system in the post-COVID-19 era remains largely unexplored. We analyzed PHC encounter counter of respiratory complaints registered in the database of the Brazilian Unified National Health System from October 2022 to July 2023. We applied EARS (variations C1/C2/C3) and EVI to estimate the weekly thresholds. An alarm was determined when the number of encounters exceeded the week-specific threshold. We used data on hospitalization due to respiratory disease to classify as anomalies the weeks in which the number of cases surpassed predetermined thresholds. We compared EARS and EVI efficacy in anticipating anomalies. A total of 119 anomalies were identified across 116 immediate regions during the study period. The EARS-C2 presented the highest early alarm rate, with 81/119 (68%) early alarms, and C1 the lowest, with 71 (60%) early alarms. The lowest true positivity was the EARS-C1 118/1,354 (8.7%) and the highest was EARS-C3 99/856 (11.6%). Routinely collected PHC data can be successfully used to detect respiratory disease outbreaks in Brazil. Syndromic surveillance enhances timeliness in surveillance strategies, albeit with lower specificity. A combined approach with other strategies is essential to strengthen accuracy, offering a proactive and effective public health response against future outbreaks.
Effect of increasing lipid levels on liver metabolism, intestinal morphology and production performance of discus fish (Symphysodon aequifasciatus)
Authors: Santos R. F. B. , Reis R. G. A. , Siqueira M. S. , Silva M. I. , Reges J. A. U. , Braz P. H. , Fantini-Hoag L. , Godoy A. C. , Honorato C. A.
Published: January 2025

Abstract The objective of this study was to evaluate the effects of three levels of lipids in the diet on growth, metabolism, and intestinal and hepatic histopathology in discus fish (Symphysodon aequifasciatus). Fish were stocked in quadruplicate in aquarium (50L) and were fed experimental diets containing three levels (3%, 10%, and 14%) of dietary lipids (LP). At the end of the trial, no significant differences in growth performance were observed. Fish fed diets with 3% and 10% LP exhibited significantly higher protein efficiency rates compared to those fed the 14% LP diet. A significant increase in lipase and alkaline phosphatase activity was observed in fish fed 14% LP diets. The inclusion of 14% lipids in the diet led to a decrease in albumin activity and an increase in the height of the intestinal villi. Although no significant differences were observed in aspartate aminotransferase, alanine aminotransferase activities, and size of hepatocytes. The histopathology of the liver indicated reduced hepatocyte size, lipid vacuoles, and sinusoidal space in the group fed the 3% LP diet. In conclusion, the use of 10% LP diet was found to be more favorable for liver health and growth performance.
Transgenderism in studies on the health of older adults: a systematic review
Authors: Arruda Jônathas de Lima , Faccio Patrícia Fernanda , Silva Camila Caroline da , Silva Danielle Ramalho Barbosa da , Moreira Rafael da Silveira , Silva Vanessa de Lima
Published: January 2025

ABSTRACT Objective To describe how transgenderism is studied in research on the health of older adults. Methods This was a systematic literature review, with searches conducted in September 2022 across the LILACS, MEDLINE/ PubMed, Embase, Web of Science and Scopus databases. The articles were selected independently by two reviewers. The risk of bias was assessed using the JBI Critical Appraisal Tools and data synthesis followed the Entreq and Swim protocols. Results A total of 15 studies were included, eight qualitative and seven quantitative, from 2014 to 2023. Most of them specifically analyzed the transgender population. The qualitative studies focused on individuals’ perceptions and experiences, health care planning and support networks. The quantitative studies addressed gender characterization, health status (including mental health), and associations with social determinants. Conclusion Despite the different approaches, the studies addressed the subject in the context of accumulated stigmas and discrimination faced this population.
Access of transgender people and transvestites to pre-exposure prophylaxis for HIV in Brazil: a descriptive study, 2018-2023
Authors: Silva Aline Pilon Mauricio da , Pereira Isabela Ornelas , Alencar Tatianna Meireles D. , Kamiensky Beatriz Brittes , Moura Marihá Camelo Madeira de , França Francisco Álisson Paula de , Morelli Thiago Cherem , Pascom Ana Roberta Pati
Published: January 2025

ABSTRACT Objectives To analyze access to pre-exposure prophylaxis (PrEP) for HIV in Brazil, comparing transgender and cisgender populations. Methods This was a descriptive study using data from the Medication Logistics Control System (Sistema de Controle Logístico de Medicamentos - SICLOM), related to the monitoring of PrEP between January 2018 and December 2023. Results During the period analyzed, 149,022 people initiated PrEP, of whom 139,423 (94%) were cisgender and 9,599 (6%) were transgender. 54% cisgender and 46% transgender people were of White/Asian skin color, 67% cisgender and 48% transgender people had 12 or more years of study, and 40% cisgender and 52% transgender people were aged 15 to 29 years. Conclusion The data showed disparities in access to PrEP, with the transgender population still underrepresented. Expanding targeted strategies may mitigate specific barriers faced by this population and promote greater equity in access to prophylaxis.
Interaction between TBMs and heavily squeezing purely cohesive grounds
Authors: Pferdekämper Thomas , Vrakas Apostolos , Anagnostou Georgios
Published: January 2025

For every increment of TBM advance under heavily squeezing conditions, the ground ahead of the face (“core”) experiences an additional axial displacement opposite to the advance direction (“extrusion”). This results in an increase in the excavation volume as the cutter-head must also excavate the extruding material. In addition, due to longitudinal arching, the deformations of the core result in an increase in shield loading. This paper investigates the effect of a large extrusion on excavation volume and shield loading by numerical and analytical methods, which consider the continuous excavation of the extruding ground. Despite the complexity of the problem, the predictions of the proposed semi-analytical and analytical methods agree very well with those of rigorous numerical simulations as well as with an empirical relationship from the literature. It is shown that in the case of heavy squeezing, the additional extrusion-induced excavation volume ("over-excavation") can be considerable. The numerical results are presented in the form of dimensionless diagrams for the ground pressure and the over-excavation, which serve the design of the shield, of the TBM thrusting system, of the cutter-head and of the mucking-out system, and the interpretation of the muck weight monitoring results during advance.
Effects of dynamic pricing on an expressway and COVID-19 impact during Tokyo 2020 Games
Authors: Akahane Hirokazu , Miyamoto Shinichiro
Published: January 2025

During the Tokyo 2020 Games, athletes and officials were required to travel from the Olympic Village to each competition venue up to 60 km away within 60 min. Various preliminary analyses were conducted on the Metropolitan Expressway (MEX), which comprised a major section of the transportation route, to assess the effectiveness of traffic management measures to avoid congestion. This study’s objective is not to verify these preliminary analyses and evaluations, but rather to examine the actual effects of traffic management measures on the MEX, especially dynamic pricing, and the impact of the spread of COVID-19 on travel on the MEX. The findings show that there was no significant correlation between the number of COVID-19 cases and the average daily traffic of users eligible for dynamic pricing before and during the Olympic Games. In addition, statistically significant effects were confirmed, including a 25% decrease in traffic volume on the MEX during the 1000 JPY additional toll period. It is estimated that the balance between traffic capacity and demand was adjusted to a level that almost eliminated congestion by reducing traffic and suppressing the emergence of latent demand through methods such as dynamic pricing.
N-acetyl-tryptophan in Acute Kidney Injury after Cardiac Surgery
Authors: Shi Ning , Wang Ji-Wen , Su Gengchen , Ma Gaoxiang , Huang Feng-Qing , Jin Si-Jia , Xie Hua-Mei , Ge Wen-Xin , Song Jiang-Ping , Luan Xiaodong , Zhang Lei , Qi Lian-Wen
Published: January 2025

Background:

Cardiac surgery-associated acute kidney injury is a common serious complication after cardiac surgery. Currently, there are no specific pharmacological therapies. Our understanding of its pathophysiology remains preliminary.

Methods:

A total of 2504 patients with and without acute kidney injury (AKI) following cardiac surgery were enrolled. High-performance liquid chromatography coupled with mass spectrometry was used for untargeted analysis of metabolites in plasma, identifying significant differential metabolites. Subsequently, a tandem liquid chromatography-mass spectrometry–based approach using isotope-labeled standard addition was performed for targeted analysis of the metabolic marker N-acetyl-tryptophan. The function of N-acetyl-tryptophan was determined using different kidney injury mouse models and epithelial cellular models. Transcriptome sequencing, surface plasmon resonance and protein mutation were employed to explore the mechanism of N-acetyl-tryptophan on the kidney.

Results:

We identified a total of 32 differential metabolites related to AKI occurrence based on a cohort of 1042 patients. Among them, N-acetyl-tryptophan was elevated in plasma of patients with cardiac surgery-associated acute kidney injury compared with those who do not develop AKI after cardiac surgery. The higher level of N-acetyl-tryptophan in plasma was confirmed by accurate targeted quantification. N-acetyl-tryptophan exhibited kidney protective effects in ischemia/reperfusion-, cisplatin-, and unilateral ureteral obstruction-induced kidney injury mouse models. Mechanistically, N-acetyl-tryptophan exerted kidney protective effects by interacting with KEAP1 at 483 and 508 sites, resulting in Nrf2 nuclear translocation and the transcription of proteasome genes.

Conclusions:

N-acetyl-tryptophan plays a key role in kidney protection.
Capitulaciones matrimoniales
Authors:   Universidad Cooperativa de Colombia, Santos Manosalva Rudht Patricia
Published: January 2025

La asignatura Derecho de Familia y el Menor se imparte con el objetivo de plantear una fase de recolección de conocimientos, la cual debe contribuir de manera significativa al desarrollo de habilidades y destrezas requeridas para desempeñarse en el área de familia. La intención es establecer el nivel en el que los estudiantes de un curso puedan sentirse unidos unos a otros, además de valorar la capacidad de proyectarse a sí mismos como personas. En cuanto al papel del estudiante, debe ser consciente de su propio aprendizaje, debe estar atento al rol que ejerce en la autodisciplina y el autoaprendizaje, y debe estudiar, analizar, reflexionar y participar en un trabajo mancomunado, ya que esto le permite proyectarse y ver con claridad la visión para lograr su objetivo.
Enhancing business communication in multinational teams: a case study on refining business english curricula
Authors: Gonchar Olena
Published: January 2025

In the current global environment, integration processes unite nations, establishing unified markets, and expanding international projects. This tendency compels designers to work in multicultural teams, where diverse worldviews, languages, and communication styles converge, with English as the standard medium for business communication. Such dynamics call for pivotal changes in design education. The research, firmly grounded in a real-life case study involving observations and questionnaires from multinational design team members in a design competition, delves into the collaborative experiences of design students from Poland,Ukraine, Bulgaria, Turkey, and Georgia. It uncovers the real challenges they face in business communication methods. The results provide educators, students, and professionals in international settings with insights that could improve the quality of teaching Business English programs to enhance the students` cross-cultural business interactions.
Scenario method in vocational German as a foreign language lessons – announcement of a pilot study for the tourism industry
Authors: Rusek Beata
Published: January 2025

In the teaching of vocational German as a foreign language, the emphasis is not on technical language, but on the language used in the workplace. The interprofessional concept of professional language highlights appropriate linguistic tools for personal and professional integrationin various work environments, regardless of the specific profession. To effectively teach German as a foreign language in preparation for communication in professional contexts,the question arises as to which methods are most suitable. This article addresses this question by focusing on the scenario method and its potential applications in the subject of German for tourism. In addition to presenting the concept of the scenario method, the article also introduces the author’s "Journey to Happiness" scenario, which is part of a pilot study planned for the winter semester 2024/2025.
Teaching business language and developing soft skills
Authors: Siwek Karolina
Published: January 2025

The aim of this article is to answer the question of how to plan and conduct the process of teaching a specialised business language (English) so that it develops linguistic and soft skills at the same time. The current labour market expects employees declaring knowledge of business language to communicate efficiently in a multicultural and changing situation, negotiate effectively, cope with stress and solve problems creatively, etc. Meeting such expectations requiresappropriate planning of the didactic process to ensure that students possess soft skills in addition to hard (language) skills. Task-based didactics emerges with help, according to which an orientation towards global simulation, case studies and projects allows psycho-social competences to be developed. This article describes a sample of tasks performed by English Philology students that could develop them linguistically, but also psychosocially. As a result of observation and feedback from the research group, it was found that task oriented didactics and individual-oriented didactics, when students are equipped with the appropriate linguistic tools and basic expertise, have positive effects on the development of soft skills.
Structural and semantic aspects of modern English medical terminology
Authors: Shpak Yuliia
Published: January 2025

Terminology is an important component of linguistics, which allows for solving many theoretical and practical issues of the formation and functioning of the terminological apparatusof various fields of human life. The current medical terminology system is not set forever in any language as new terms continue appearing constantly and intensively. The object of the study was medical terminology of the modern English language. This study aims to give a general characteristic of main structural and semantic types of medical terms. The research was based on the material from textbooks on medical terminology and specialized dictionaries. Thus, the study demonstrates some patterns of term structures related to ways of forming new vocabulary in general. Based on the lexical semantic approach, the studied examples of medical terminology were divided into eight thematic groups.
[Rev.] On the anniversary of the outstanding Ukrainian scientist. Florij Batsevych
Authors: Sazonova Yaroslava
Published: January 2025

This introduction aims to honor the achievements and contributions of Professor Florij Batsevych (Ukraine) on his 75th birthday, acknowledging his impact on the field of linguistics with particular emphasis on the Ukrainian-Polish cooperation and encouraging further explorationand research inspired by his work.
Tecendo narrativas: cuidado suficientemente bom em uma USF na pandemia de covid-19
Authors: Costa Lara Irene Leite da , Maciazeki-Gomes Rita de Cássia
Published: January 2025

Esse artigo apresenta um estudo narrativo que objetiva compartilhar as experiências, de uma psicóloga residente, durante a pandemia de COVID-19. Articula relações entre Saúde Coletiva e Psicanálise, trazendo as diretrizes da Política Nacional de Humanização (PNH) e os conceitos da teoria do amadurecimento de Donald Woods Winnicott para pensar um cuidado possível, ou suficientemente bom, no trabalho multiprofissional em saúde, em uma Unidade de Saúde da Família, na região sul do Brasil. Como estratégia metodológica foi utilizada a pesquisa narrativa. Para a produção dos dados foram realizados registros do cotidiano de trabalho em diário de campo, emergindo três temas de análise: valorização do trabalhador, ambiência e acolhimento. O processo de análise esteve ancorado nas articulações entre as diretrizes da PNH e conceitos da psicanálise Winnicottiana. para dar sentido e corpo às discussões. Os dados produzidos apontam que o cuidado suficientemente bom em saúde pública está fortemente atrelado às diretrizes da constituição de espaços receptivos, acolhedores para as demandas que chegam à atenção primária, e ainda, a implementação de estratégias de reconhecimento de valorização do trabalho em saúde. A pesquisa narrativa realizada possibilitou, não só a própria reflexão sobre as práticas de cuidado empregadas em campo, mas também contribuiu para que outros profissionais da atenção básica possam tecer um cuidado suficientemente bom a partir do preconizado nas diretrizes da PNH e das contribuições da psicanálise de D. W. Winnicott.
Vínculo afetivo pessoa-ambiente em desastres: análise barthesiana de imagens de atingidos
Authors: Hodecker Maísa , Felippe Maíra Longhinotti , Bousfield Andréa Barbará da Silva
Published: January 2025

Os desastres socioambientais ocasionam impactos generalizados na vida das pessoas, inclusive nos vínculos que possuíam com o lugar. Objetivou-se descrever a vinculação afetiva pessoa-ambiente em suas dimensões funcional, simbólica e temporal por meio de uma análise barthesiana de imagens fornecidas pelos atingidos. Trata-se de uma pesquisa qualitativa do tipo documental que adota um caráter descritivo-exploratório. Participaram da pesquisa sete pessoas atingidas (cinco do gênero feminino; dois do gênero masculino), com média de idade de 46 anos e 5 meses. O estudo revelou que, após o desastre, os vínculos afetivos com o ambiente foram modificados, apesar da reconstrução e retomada da funcionalidade. As fotografias demostram que a vinculação afetiva e permanência no ambiente é influenciada pelas memórias afetivas, significados de lugar e importância no desenvolvimento da identidade, a história das famílias. Percebeu-se que a dimensão simbólica e temporal associadas sobressaem à funcional. Apesar da reconstrução do lugar, não houve a restauração dos sentimentos de segurança e apropriação, evidenciando que os impactos emocionais são tão significativos quanto os materiais.
Vivências da enchente: o brincar e a criatividade infantil com as telas
Authors: Sehaparini Indianara , Marques Fernanda Martins , Sebben Sofia , Lawall Cailane , Aguiar Marina Furlan de Oliveira , Frizzo Giana Bitencourt
Published: January 2025

As redes sociais tornaram-se plataformas importantes para o compartilhamento de experiências pessoais durante eventos desafiadores. Cuidadores frequentemente utilizam essas plataformas para divulgar vídeos de seus filhos, incluindo conteúdos criados pelas próprias crianças como parte do brincar virtual. Contudo, o compartilhamento de experiências infantis em redes sociais, particularmente em eventos climáticos extremos, ainda demanda maior investigação, especialmente quanto ao seu potencial para informar respostas a crises futuras. Este estudo analisou, por meio de uma netnografia nas plataformas Instagram e TikTok, as experiências de crianças compartilhadas por seus responsáveis durante as enchentes de 2024 no sul do Brasil. Foram examinados nove vídeos utilizando análise temática reflexiva. Os resultados evidenciaram a centralidade do brincar, inclusive com telas, e a importância dos brinquedos como símbolos de lar nas vivências infantis. Observaram-se também expressões de gratidão das crianças pelas doações recebidas, destacando o papel do apoio social em momentos de crise. As crianças assumiram um papel ativo nos vídeos, adaptando criativamente o estilo de influenciadores digitais para promover ações de solidariedade. Embora os vídeos tenham dado visibilidade às experiências infantis, eles levantam questões sobre a exposição das crianças nas redes sociais e seu direito à privacidade, reforçando a responsabilidade de segurança digital por parte de seus cuidadores. Conclui-se que as telas podem ser aliadas no estímulo ao brincar criativo, sendo essencial oferecer condições para o brincar tanto on-line quanto off-line, especialmente em contextos de eventos climáticos extremos.
ATIVIDADE FÍSICA E SAÚDE EM ESTUDANTES UNIVERSITÁRIOS NA PANDEMIA DE COVID-19: uma revisão sistemática
Authors: De Goveia Jean Carlos , Moleta Vargas Thaiane , Herrera Cantorani José Roberto , Pedroso Bruno , Martinez Vargas Leandro
Published: January 2025

Introdução: as medidas de isolamento social e restrições de acesso às universidades podem ter sido preditoras para a mudança no estilo de vida dos estudantes e desencadeado alterações psicológicas, físicas e sociais, em consequência das constantes alterações na vida diária. Objetivo: analisar a produção científica sobre o nível de atividade física e fatores associados à COVID-19 em estudantes universitários. Método: trata-se de uma revisão sistemática de literatura e mapeamento bibliométrico, em periódicos internacionais indexados na base de dados PubMed, utilizando os descritores: Physical activity AND College students AND COVID-19. Foram incluídos artigos científicos originais publicados entre 2020 e 2022, resultando em 226 artigos iniciais, destes, 18 estudos foram incluídos na síntese. Resultados: constatou-se uma diversidade de evidências acerca da atividade física durante o isolamento social, bem como, as pesquisas relataram lacunas e possíveis intervenções no contexto universitário diante ao acontecimento da COVID-19. Em todos os estudos analisados, o comportamento sedentário e os níveis de atividade física oscilaram quando comparados os cenários antes e durante a pandemia. Conclusão: os estudantes que mantiveram ou aumentaram seus níveis de atividade física apresentaram menor probabilidade de desenvolver sintomas de ansiedade, depressão e estresse. Sugere-se mais pesquisas longitudinais abrangentes para aprofundar essas conclusões. Além disso, é fundamental que as instituições de ensino superior promovam educação em saúde, forneçam infraestrutura adequada e apoiem programas adaptados para incentivar a prática regular de exercícios, visando o bem-estar dos estudantes durante e após períodos pandêmicos futuros.
COMER EMOCIONAL DE PESSOAS COM DOENÇAS METABÓLICAS DE UM HOSPITAL UNIVERSITÁRIO NO RIO GRANDE DO SUL
Authors: Gonçalves Gabbardo Francine , Marion da Silva Rosângela , Ceni Giovana Cristina , Arend Birrer Jucelaine , Freitas D’avila Helen , Souza dos Santos Gilvane
Published: January 2025

Introdução: este artigo traz como eixo norteador situações em que a alimentação é utilizada como resposta a alguma desregulação emocional por pessoas com doenças metabólicas. Objetivo: identificar a presença do comer emocional em usuários do ambulatório médico de endocrinologia e do ambulatório multiprofissional de doenças crônicas da residência multiprofissional, de um hospital universitário no interior do Rio Grande do Sul Método: estudo transversal e descritivo, realizado com usuários que apresentavam alguma alteração metabólica, acompanhadas em um ambulatório de endocrinologia de um hospital universitário da região central do RS. Para coleta de dados foi utilizado um formulário com questões socioeconômicas e de autocuidado, além destes para identificar o comer emocional foi utilizado o questionário Emotional Eater Questionnaire (EEQ). Foram realizadas análises estatísticas descritivas. Resultados: participaram 50 usuários, com predomínio do sexo atribuído no nascimento feminino (80%), residentes no município sede da pesquisa (42%), com faixa etária entre 31 e 59 anos. Evidenciou-se maior percentagem de usuários que realizavam algum tipo de acompanhamento psicológico (52%) e que tinham diagnóstico de pré-diabetes (56%). Com relação ao comer emocional, predominou a classificação como comedores emocionais (34%), seguido pelos comedores emocionais baixos (26%), comedores muito emocionais (22%) e comedores não emocionais (18%). Conclusões: foi identificado que os pacientes com alteração metabólica se enquadram em algum nível de comedores emocionais. Utilizar a alimentação como estratégia para aliviar as dores emocionais pode, ao longo do tempo, prejudicar a condição de saúde.
PREVALENCE AND FACTORS ASSOCIATED WITH NON-PARTICIPATION IN PHYSICAL EDUCATION CLASSES IN SCHOOL ADOLESCENTS OF SERGIPE
Authors: Guerra Marcelo Freire , Magalhães Sales Marcelo , Smith Menezes Aldemir , Viera Tavares Luis Carlos , Lira Luís Carlos , Vila Nova de Moraes José Fernando , De Deus Bezerra Mairiel Leila , Santos Karllos Henrique , Santos Nascimento Lucas , Rodrigues Vilela Gabriella , Wander Cantão Elbert , Souza Sá Filho Alberto , Silva Márcia Cristina
Published: January 2025

Introduction: The frequency in physical education (PE) classes, beyond being low, tends to decrease with the passing of school years, suggesting an understanding of the factors for possible intervention. Objective: The objective of this study was determining the prevalence and risk factors associated with absence in PE classes. Method: In the research, 3.992 students were investigated about participation in PE classes, socioeconomic, demographic, and behavioral conditions. Results: The results revealed that 25.7% of students are absent in PE classes. Skin color, religious observance, household situation and shift study were associated with the outcome (absence in PE classes). Between girls, the outcome was associated with skin color, religious observance, situation of domicile and period of study; whereas for boys, only the situation of domicile and the period of study. Conclusion: One could conclude that the absence in PE classes is relatively high and that girls showed more associated risk factors.
Keywords: Motor Activity; Health; Adolescent Behavior.