bluuebunny/crossref_metadata_2025 huggingface dataset:
Production Scheduling of Open Pit Mine Using Sequential Branch-and-Cut and Longest Path Algorithm: An Application from an African Copper Mine
Authors: Joshi Devendra , Satpathy Susanta Kumar
Published: November 2020

Open pit mine production scheduling assigns mining blocks in different production periods for maximising profits after satisfying geotechnical and operational constraints. In this paper, two Open pit mine production scheduling models were applied in an African copper deposit. The first model is a traditional model with more tight resource constraints; the second model is a more robust model where resource constraints are relaxed by penalizing the objective function. Both the models were solved using two step algorithms: (a) year wise production scheduling using a sequential branch-and-cut algorithm; and (b) an iterative longest path algorithm to improve the solution generated from branch-and-cut. Results demonstrated that due to the tight constraints in Model 1, the optimizer was unable to generate a feasible solution after the first period, therefore the lower limit metal production constraint was eliminated to generate a feasible solution; however, Model 2 was able to generate a feasible solution for all periods. Results show that both the models generated nearly the same amount of ore, waste, metal content, and mine life. Model 2 generates relatively more net present value as compared to Model 1, whereas, the computational time required for solving the scheduling problem is relatively less for Model 1 than for Model 2.
Robust Control and Stability Analysis of Computerized Numeric Controlled Machine Tool under Parametric Uncertainty
Authors: Yadav Anil Kumar , Pathak Pawan Kumar , Gaur Prerna
Published: November 2020

The objective of this paper is to design three different robust controllers such as proportional-integral (PI), internal model control (IMC), and H∞ control techniques for position control of the computerized numeric controlled machine tool (CNCMT) system. The proposed controllers aim to control the servo motor that regulates the position of the machine table and also enhances the robustness of the CNCMT system under the influence of parametric uncertainties. The stability of the uncertain CNCMT system with all designed controllers is investigated using Kharitonov’s theorem. The stability margin (SM) criterion is utilized for robustness analysis.
Experience of lifelong education in Western countries: The revelation of adult education
Authors: Zhou Haiying
Published: November 2020

Summary Adult Education in China provides a large number of educational opportunities for the general public , trained a large number of talented people , The largely compensates for higher education's Insufficient , But there are many problems . the appearance of these problems directly or indirectly affects the quality of education for adult teaching . , affect lifelong education in our country The construction of the system . for This, should draw on the successful experience of lifelong education in Western countries , combined with China's national conditions , Clear the concept of adult education goal , make adult education Education Development Program , Improving the quality of teaching for adults , Further promote the development of lifelong education in our country .
Jameson's View of the Third World Literature
Authors: Ma Bin
Published: November 2020

Jameson takes the political system as the standard to classify the three worlds. He thinks that the first world literature is more mature and perfect than the second and third world literature in terms of literary types and theoretical research. The nationalism that the second and third worlds are keen to explore has been cleared up in the first world and has long been out of date. What they can do is to accept the influence of American principles of free market and postmodernism. He asserted that the first world literature was the competitor and criterion of measuring the achievement of that of the third world. The result was undoubtedly disappointing. It was due to his identity and a higher self-positioning as the first world critic.
On the Role of Multicultural Education in English Teaching
Authors: Liu Honglan
Published: November 2020

The continuous changes in society and the rapid development of the economy have gradually integrated multiculturalism into people's lives, and have exerted an important influence on their ideological and moral standards, values and behavioral awareness. Therefore, how to effectively introduce the theory of multicultural education into classroom teaching activities and ensure the rapid improvement of teaching effectiveness has become a key research issue for many teachers. From different perspectives, the author explores specific ways to promote the smooth development of English classes in colleges and universities under the multicultural background, hoping to provide references for other college English teachers.
Teaching Reform and Practice Exploration of Medical Biochemistry Theory Course
Authors: Jia Jun
Published: November 2020

Biochemists lack understanding of professional medical knowledge, and clinicians have very little understanding of biochemistry, which makes it difficult to teach medical biochemistry theory. However, with the rapid development of life sciences, the demand for high-quality medical personnel in today’s society has also become higher and higher. Therefore, it is necessary to link biochemistry with medicine, and at the same time learn from the teaching concepts of biochemistry, to explore several ways to improve the teaching quality of medical biochemistry theory courses.
Qualitative Research on Learning Experience of Mixed Teaching
among Nursing Students in Higher Vocational Colleges
Authors: Chen Liqin , Ren Ning , Zhang Rui , Fu Baoqin
Published: November 2020

Purpose To investigate experiences of vocational college students majoring in nursing on mixed teaching and to provide reference for the further improvement of mixed teaching.
Method Using the purpose sampling method, 8 students were selected for semi-structured interviews, and Colaizzi phenomenological analysis was used to analyze the data.
Results Four core themes were extracted.: (1) The ability of autonomous learning was enhanced and classroom participation was increased; (3) The overall progress of online learning was not well controlled. The study was not thorough; (4) Online and offline teaching were disconnected, and teacher-student interaction was low. Conclusion The mixed teaching has improved the self-learning ability and classroom participation rate to a certain extent, but further efforts are needed in optimizing the teaching platform, improving the teacher’s mixed teaching ability, and maintaining students’ learning enthusiasm.
Discussion on Improving the Political Identity of College Students in
the Network Environment
Authors: Liu Ru
Published: November 2020

With the in-depth reform of China’s higher education system, the status of ideological and political education in colleges and universities plays a pivotal role, and the political identity of college students has developed rapidly. Under the traditional education system, colleges and universities attach great importance to increasing political identity education in ideological and political theory courses. Under the current new situation, college students are the most active group on the Internet, and they are accustomed to expressing opinions and attitudes on different events through the Internet. Therefore, it should be aware of the importance of enhancing the political identity of college students under the network environment, and give full play to the role of the Internet in cultivating college students’ political identity. This article focuses on the issues related to enhancing the political identity of college students in the network environment, and enhancing the political identity of college students.
Cultivation and Improvement of Students’ English Reading Ability in Higher Vocational Colleges
Authors: Qi Lin
Published: November 2020

With the effective implementation of quality education, the teaching reform is accelerating, and the cultivation of comprehensive literacy abilities of vocational college students has become the focus of teaching. Therefore, vocational English teaching pays more attention to improve students’ reading ability. Based on the actual teaching practice, this article analyzes the current situation of English reading learning for vocational students and discusses countermeasures of improving students’ English reading ability, hoping to give certain enlightenment on promoting the overall quality of vocational English teaching.
Reform of College English Teaching from the Perspective of Ideological and Political Education
Authors: Wei Chunyan
Published: November 2020

The fundamental task of education is to foster morality. Strengthening ideological and political education is an important means to cultivate people with moral integrity. To integrate ideological and political education into teaching, it is necessary to shift from “giving ideological and political courses” to “giving ideological and political education in all courses”. Teachers in colleges and universities should actively promote the ideological and political reform of college English courses through innovating teaching modes, expanding educational channels, digging deeply into the teaching resources for ideological and political elements, optimizing teaching designs, and realizing the deep integration of moral education with college English teaching, to give full play to the role of college English in ideological and political education.
Current Situation and Development Strategy of Preschool Art Education
Authors: Xiao Shufang , Xiao Zhiyuan
Published: November 2020

In recent years, with the continuous deepening of education reform, the education sector has put forward higher requirements for early childhood education. It is necessary to give full play to the advantages of art education and cultivate the creativity of young children. At this stage, there are still many problems in children's art education, which is not conducive to the cultivation of children's creative ability. Under the new educational background, it is necessary to innovate children's art education models and cultivate children's artistic literacy.
Analysis on Teaching Measures of Logistics Management Major in Applied Universities from the Perspective of Supply-side Reform
Authors: Zuo Yujie
Published: November 2020

Under the background of supply-side reform, colleges and universities pay attention to the cultivation of application-oriented talents to meet the needs of social development. Taking the logistics management major of colleges and universities as an example, teaching reform measures are proposed from the background of supply-side reform.
Discussion on the Cultivation of Technical Talents of Landscape
Architecture in Applied Undergraduate Colleges
Authors: Fan Lei , Zhou Yan
Published: November 2020

With the continuous development of the economy, the construction of ecological civilization in my country has become an important part of the construction of modern cities. In order to achieve this construction goal, a large number of applied technical talents in landscape architecture need to be invested. This paper analyzes the demand for the cultivation of applied technical landscape architecture talents, further clarifies the goal of training landscape architecture professionals, and discusses the training model of applied landscape architecture professionals.
CONCEITOS E FUNDAMENTOS DOS DIREITOS HUMANOS PARA PROFISSIONAIS DE ENFERMAGEM EM UNIDADE DE EMERGÊNCIA
Authors: Borges Tyciana Paolilo , Anjos Karla Ferraz dos , Magalhães Julia Barbosa de , Schulz Renata Da Silva , Santa-Rosa Darci De Oliveira
Published: November 2020

Objetivo: apreender conceitos e fundamentos sobre direitos humanos na compreensão de profissionais de enfermagem em unidade de emergência hospitalar. Método: pesquisa fenomenológica realizada com 11 profissionais de enfermagem. As entrevistas foram gravadas e a interpretação dos dados deu-se pela configuração Triádica Humanística Existencial Personalista, embasada na Declaração Universal dos Direitos Humanos. Resultados: emergiram duas categorias “Profissionais de Enfermagem conceituam os direitos tomando como referência a Declaração Universal dos Direitos Humanos” e “Profissionais de Enfermagem fundamentam a compreensão sobre Direitos Humanos em princípios bioéticos e valores”. Saúde, habitação, segurança, cuidados médicos e sociais foram expressos como direitos humanos. O respeito ao outro e aos Direitos Humanos foi compreendido como independente da condição de hospitalização. Conclusão: as profissionais de enfermagem compreendem os Direitos Humanos com base na Declaração Universal dos Direitos Humanos. Os aspectos bioéticos e valores que emergiram como fundamentos para essa compreensão foram autonomia, dignidade, beneficência, alteridade e privacidade.

Descritores: Direitos Humanos. Cuidados de Enfermagem. Bioética. Emergências.
Przewaga komparatywna krajów Andyjskiego Wspólnego Rynku (CAN) w międzynarodowym handlu towarami z Mercosur
Authors: Majcher Kamil
Published: November 2020

Celem artykułu jest określenie przewag komparatywnych w handlu towarowym czterech krajów ugrupowania CAN nad pięcioma krajami ugrupowania Mercosur w latach 2007–2017. W tym celu zastosowano wskaźnik ujawnionych przewag komparatywnych Balassy oraz klasyfikację towarów SITC (standard international trade classification). Badanie poprzedzono omówieniem międzynarodowych obrotów towarowych CAN z Mercosur.
Przeprowadzone badanie ujawniło przewagę komparatywną CAN w następujących segmentach klasyfikacji towarowej SITC: trzecim (surowce mineralne, smary i podobne materiały), ósmym (inne wyroby przemysłowe) oraz dziewiątym (inne wyroby niesklasyfikowane). Szczególnie wysoką wartość RCA w latach 2007–2017 odnotowano w przypadku segmentu trzeciego. Świadczy to o dużym znaczeniu towarów przemysłu wydobywczego dla gospodarek narodowych należących do CAN.
Nowe technologie w terapii logopedycznej dzieci z zaburzeniami mowy
Authors: Jatkowska Joanna
Published: November 2020

Polska logopedia wykorzystuje technologie informacyjno-komunikacyjne (TIK) w diagnozie i terapii od ponad trzydziestu lat. Początkowo logopedzi korzystali ze światowych aplikacji, by w latach dziewięćdziesiątych XX zacząć tworzyć własne programy komputerowe, dostosowane do specyfiki języka polskiego. Wraz z rozwojem internetu pojawiły się logopedyczne platformy e-learningowe. Jedną z nich autorka niniejszego artykułu wykorzystała w terapii logopedycznej dzieci z zaburzeniami mowy, by sprawdzić, czy nowe technologie mogą przyczyniać się do poprawy artykulacji. Przeprowadzony eksperyment pedagogiczny pokazał, że autorska koncepcja b-learningu może być skuteczna w terapii logopedycznej dzieci.
Konceptualizacje głosu
Authors: Kaźmierczak Monika
Published: November 2020

Głos jest istotnym elementem życia człowieka. Współcześnie przedmiot zainteresowania stanowi zarówno materialna, formalna, jak i symboliczna warstwa głosu. Niemożność jednoznacznego i pełnego zdefiniowania pojęcia oraz identyfikacja różnych funkcji głosu w relacji z podmiotem i Innymi dowodzi konieczności uwrażliwienia na głos – nie tylko w jego bardziej ujęzykowionej formie, podczas komunikacji bezpośredniej, ale również jako ekspresji bądź wymiany wokalnych sygnałów i znaków czy istotnej składowej tożsamości komunikującego się podmiotu. Przytoczone w artykule konceptualizacje głosu potwierdzają, że obszary jego badania w wymiarze indywidualnym i społecznym są ze sobą ściśle związane.
Budowa graficzna pisma oraz zaburzenia w strukturze wyrazów na przykładzie wybranych próbek tekstów pisanych przez dorosłe osoby z dysleksją
Authors: Szurek Marzena Maria
Published: November 2020

Artykuł podejmuje wątek deficytów językowych wynikających z dysleksji, dotyczących osób dorosłych i manifestujących się zaburzeniami języka pisanego. Tym samym próbuje odejść od tradycji badań nad dysleksją, które w większości koncentrują się na okresie nauki szkolnej i problemach edukacyjnych. Oprócz wybiórczej analizy językoznawczej próbek tekstowych, która stanowi główną część pracy, w tekście zwrócono też uwagę na ogół symptomów występujących u dorosłych z dysleksją, które w znacznym stopniu mogą komplikować codzienne funkcjonowanie.
Brasil nuclear: dos interpretaciones opuestas sobre la orientación de su programa atómico
Authors: Morales Giraldo Juan Francisco
Published: November 2020

The analysis of the Brazilian nuclear program from different theoretical approaches shed light on differences regarding its orientation and purposes. Optimistic views, from a liberal standpoint, emphasize the idea that States’ foreign policy should be asses in a favorable fashion according to certain aspects such as democratic values, compliance with international norms and legitimacy from public opinion. But in opposition to perspectives based on normative arguments, a power politics perspective emphasizes least idealist aspects: the reconfiguration of international power hierarchy and the aspirations of an emergent global power as subjacent motivations for the technical developments of the atomic program. This work ponders the relative utility of both perspectives focusing on situations, developments and discourses from recent past that make possible to infer the political orientation of Brazilian nuclear program. The study proceeds by contrasting the evidence available with theoretical elements from each perspective. First, Brazilian foreign policy regarding the Nonproliferation Regime is compared with assumptions from Liberal thesis about State conduct. In that sense, aspects such as the weight-normative international institutions, domestic democracy and legitimacy provided by these principles, would have an important explanatory importance. In the second part, an opposed view is adopted: the liberal thesis applied to the problematic of Brazilian nuclear program are seen critically from the standpoint of an interpretation about its orientation based on a revisionist policy and pragmatism related to major objectives of international status and power relations with Great Powers. An important evidence in that sense is the ambiguity of the nuclear program and its military purposes, which suggest that the second perspective offers a better explanation of Brazilian objectives in this area. Conclusions are focused on three distinctions between both perspectives that give answers to the problems of the study: the absence of a nuclear program in contrast with the militarization of the nuclear technology and its applications; the acceptance of international institutions in contrast with the pragmatism and selectiveness of the compliance of certain principles; and finally, the unclear conceptual frontiers exposed by the Brazilian nuclear program.
Consciência do oprimido: uma leitura freiriana de Lima Barreto
Authors: Carvalho de Matos Leonardo Raphael
Published: November 2020

“Consciência do oprimido: uma leitura freiriana de Lima Barreto”, de Carlos Mario Paes Camacho, que analisa “O triste fim de Policarpo Quaresma”, de Lima Barreto, publicada em 1915, à luz das concepções de Paulo Freire, especialmente as questões da consciência e as contradições da sociedade brasileira. A obra de Lima Barreto persegue a “razão oprimida”, ou seja, a existência de racionalidades desenvolvidas pelas classes subalternizadas e que foram silenciadas pelo poder das classes dominantes.
Pediatria do Neurodesenvolvimento em Portugal: Movimento Hospitalar Assistencial, Recursos e Necessidades – Evolução em Dez Anos
Authors: Oliveira Guiomar , Nunes Vicente Inês , Guardiano Micaela , Aguiar Liza , Loureiro Susana , Gouveia Rosa , Glória Silva Filipe
Published: November 2020

Introdução: As perturbações do neurodesenvolvimento são, nas sociedades modernas, as patologias crónicas mais frequentes da idade pediátrica. Muitas permanecem na vida adulta. A organização da rede de cuidados de saúde nacional carece de conhecimento fundamentado das necessidades assistenciais para lhes responder de um modo eficaz, eficiente e efetivo. Com o objetivo de conhecer a realidade assistencial hospitalar atual da Pediatria do Neurodesenvolvimento, a Sociedade de Pediatria do Neurodesenvolvimento da Sociedade Portuguesa de Pediatria procedeu a um levantamento nacional em 2007, repetindo-o dez anos depois.Material e Métodos: No biénio 2016-2017 procedeu-se a um inquérito dirigido ao universo de 45 unidades hospitalares abrangendo o movimento assistencial das consultas de Pediatria do Neurodesenvolvimento, a alocação de recursos humanos, e as necessidades de reforço de profissionais.Resultados: Obteve-se 100% de respostas. O número total de consultas de Pediatria do Neurodesenvolvimento subiu de 38 238 (2007) para 99 815 (2017). O número de profissionais também aumentou: os pediatras passaram de 82 a 156. Uma mediana de 101 crianças aguardavam primeira consulta, contra 185 em 2007.Discussão: Numa década, o movimento assistencial quase triplicou. O reforço de profissionais, apesar de positivo, não teve o mesmo incremento; ainda assim, o número de crianças em lista de espera para primeira consulta reduziu-se quase para metade, o que reflete o comprometimento dos profissionais.Conclusão: É de salientar a melhoria global da resposta nacional na área da Pediatria do Neurodesenvolvimento. Contudo, o reforço dos recursos humanos numa perspectiva pluridisciplinar não deve ser negligenciado, tendo em vista a melhoria contínua da prestação de cuidados numa área de grande cronicidade e complexidade.
THE ANALYSIS OF VILLAGE MIDWIFE PERFORMANCE IN REDUCING MATERNAL AND INFANT MORTALITY RATE
Authors: Hiola Tumartony Thaib , Badjuka Bun Yamin M.
Published: November 2020

Background: The most essential aspect to reduce the number of maternal and newborn mortality is midwife competence. Midwives have a great role to be able to handle variety of health services (antepartum, intrapartum, and postpartum) to avoid or decrease the maternal and infant mortality rate. Performance of health workers, particularly midwives, is the most crucial in affecting the quality and quantity of midwives’ services to  enhance the national health development.Aim: This study analyzed factors affecting village midwife performance for reducing maternal and infant mortality in seek for achieving Bone Bolango cemerlang or bright Bone Balango as the vision of Bone Bolango District in 2021.Methods: This study was an analytical survey with a cross-sectional approach. It was conducted from March to June 2019 in the working area of Bone Bolango District Health Office. There were 227 people from 19 primary healthcare centers as the population, and the sample size was 227 selected by using the total sampling technique. The data were collected by distributing questionnaires to the respondents and using secondary data. The data processing was done through chi-square test and multiple logistic regression with backward wald method.Results: Midwife performance in Bone Bolango District was assessed based on several variables. Most of them were ≥ 25 years old (80.6%); worked for ≥ five years (58,6%); mostly had not participated in any normal childbirth care training (76.7%); had a good competence (96.5%); had good resources/equipment (79.7%); had a good reward (92.5%); had a good attitude (76.2%); had a good motivation (90.7%). There were 12 maternal mortalities from 2017 to 2019 handled by only 11 midwives (4.8%). On the other hand, infant mortality rate (IMR) reached 25 cases in the same years; of 227 midwives, these cases were handled by only 21 midwives (9.3%).Conclusion: A midwife as a part of the health workers has an important role to increase the quality of maternal and child well-being program. Some variables that became indicators of midwife performance and had an effect on reducing the MMR and IMR included work period, reward, and motivation. This study recommends that all midwives have to be provided with a normal childbirth care training in the working area and increased rewards in the process of labor and delivery. Keywords: midwives, performance, maternal mortality rate, infant mortality rate.
CRITERIA AND INDICATORS OF VILLAGE PREPAREDNESS ON FOREST AND LAND FIRES CONTROL
Authors: Budiningsih Kushartati , Malik Setiabudi Irfan , Yosefi Suryandari Elvida , Djaenudin Deden , Iqbal Mohamad
Published: November 2020

The government have prioritized forest and land fires issue become one of their national priorities. Villagebased fire control Approach have been Developed by Encouraging community involvement. That approach considers an existence of village as the site-smallest administrative entity and also fire events occur within village. The validated criteria and indicators are utilized as an instrument for assessing the preparedness performance of villages, specifically on fires control. Those instruments comprise 5 criteria and 20 indicators, which represent their different weight for each. The criteria encompass community participation, technology and infrastructure, land and livelihood, fire control team, and fire control policy. Those instruments have been developed in 5 provinces, comprise South Sumatra, Jambi, West Kalimantan, Central Kalimantan, and South Kalimantan. Thus, it can generate classification of fire-preparedness village as following Class A (Good), B (Moderate), and C (Poor). Tarung Manuah (Central Kalimantan) and Jangga Baru (Jambi) villages are an example of village which have a good preparedness condition on fire control (Class A). This assessment tool is easy to use and can be practiced by all parties, in the form of self-assessment. Further, this instrument and its classification can be optimized as a basis for village-based program interventions on conducting fire control.
Effect of Strontium doping on Thermal and
Optical properties of Gel grown Copper cadmium and Cobalt
cadmium oxalate crystals
Authors: Rohith P. S , N Jagannatha , K.V Pradeepkumar
Published: November 2020

In the present paper, the Sr2+ doped Copper cadmium oxalate (CuCO) and Cobalt
cadmium oxalate (CoCO) crystals were grown by the single diffusion method in silica
hydrogel at room temperature. Optimum conditions of the as-grown crystals were established
by varying different growth parameters. Energy-dispersive X-ray analysis (EDX) confirmed
the presence of major elements such as Sr2+, Co2+, Cu2+, Cd2+ ions in the lattice of the grown
crystals. The percentage weight loss, molecular weight and thermal stability of the grown
crystals were studied using Thermogravimetric analysis (TGA). The Energy gap, refractive
index, reflectance and electrical polarizability of the crystals were calculated by using UVVisible
spectroscopy. Direct and Indirect band gaps are calculated using Tauc’s plot
Review on the Bioactivities of Quercetin
Authors: Shabana  , Jaysree R. C. , N Rajendran .
Published: November 2020

Quercetin, the most active bioflavonoid which is produced as a secondary
metabolite by plants, is a polyphenol with a wide spectrum of bioactivities. This bioflavonoid is
the ―nature‘s biological response modifier‖ as it interferes with the various allergens and
other reactive compounds. Apple, oranges, tomatoes, onions, black tea and green tea are good
sources of quercetin and it is also available commercially. After absorption in the small
intestine and colon, quercetin conjugates with glucuronic acid and binds to albumin and passes
to liver and benefits the body by its various bioactivities. Quercetin‘s antioxidant activity
enhances the radical scavenging activity and metal chelation of the ions but the prooxidant
activity depends on its high concentration. Further, quercetin interferes with the formation of
leukotrienes from arachidonic acid showing its anti-inflammatory effect. A combined effect of
quercetin and bromelain effectively suppresses the allergic reactions and the excessive
inflammation resulting from bruising and tissue damage. The mutualistic effect of vitamin C
and quercetin protects each other from getting oxidized. A direct relationship was also found
to exist between quercetin's antiviral activity and enhancement of cyclic adenosine
monophosphate (cAMP), which is a second messenger involved in many biological processes.
Quercetin helps in down regulation of mutant gene p53 and inhibits the growth of cancerous
cells by putting a check at G1 phase. This also controls the surpassing of the normal regulatory
growth by the tumor cells and inhibits the production of heat shock proteins and thus showing
its anticancer properties. Owing to the potential pharmaceutical properties of quercetin, the
bioactivities, principle uses and mechanisms involved in the treatment of various diseases
were reviewed in this paper. In addition, safety issues involved in the partake of quercetin by
humans have also been discussed.
Spectrophotometric determination of Clinidipine, Efavirenz,
Prazosin drugs by using Folin-Ciocalteu Reagent
Authors: Pailla Naveen Reddy , Kuthati Bhaskar
Published: November 2020

For the determination of three drugs namely Cilnidipine (CDP), Efavirenz (EVZ),
Prazosin (PRZ), a simple, fast, selective and accurate spectrophotometric method has been
outlined. This method is based on the development of blue coloured chromogen due to
reduction of tungstate and/ or molybdate in Folin-Ciocalteu reagent by Drug in alkaline
medium. The coloured species has an absorption maximum at 730 nm, 745 nm and 770 nm
and the Beer’s law obeys over the concentration range of 12-72 μg/mL, 10-70 μg/mL, 3-21
μg/mL respectively for the drugs CDP, EVZ, PRZ. This method has been validated according
to ICH guidelines and applied to the analysis of pharmaceuticals.
Spectroscopic Studies and Vibrational Assignments, Homo-
Lumo, UV-VIS, NBO Analysis of Benzonitrile
Authors: Rajalakshmi K. , Sharmila S.
Published: November 2020

The Fourier transform infrared and FT-Raman spectra of Benzonitrile have
been recorded in region of 4000-400 and 4000-100 cm
-1
respectively. A complete
assignments and analysis of fundamental vibrational modes of the molecule have been carried
out. The observed fundamental modes have been compared with harmonic vibrational
frequencies computed using ab initio and density functional theory calculations by employing
B3LYP functional at 6-311G(d, p) level and HF/6-311G(d, p).UV-Vis spectrum of the
compound has been recorded, the natural bond orbital (NBO) electronic properties, such as
highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital
(LUMO) energies have been calculated with B3LYP/6-311G(d, p) level. These calculated
energies show that charge transfer occurs within molecule. NBO analysis, thermodynamics
properties and Mulliken charges of the title molecule are also calculated and interpreted
Phytochemical Analysis and Anti-microbial Studies of Leaf
Extract of Terminalia arjuna using Spectroscopic Methods
Authors: Anita B.
Published: November 2020

From time immemorial plants have been used as potent therapeutic agents to treat various ailments
in the Siddha and Ayurveda streams of medicine. Plants are rich sources of flavonoids, alkaloids, terpenoids
and other related polyphenols. One such important plant used for treating heart ailments is Terminalia arjuna.
The bark of this plant plays a vital role as cardiac tonic. It also possesses antimicrobial, cytotoxic and
antidiabetic properties. The phytochemical activity of the secondary metabolites present in the bark of
T.arjuna has been reported widely. But, the medical uses of leaf extract of the plant have seldom been
reported. In this work, the ethanolic extract of leaf of T. arjuna has been analysed for the presence of different
phytochemicals using FTIR, UV-Visible and GC-MS spectroscopic methods. The various functional groups
present in the leaf extract have been identified initially using FTIR and UV-Vis spectra of leaf extract. Next,
GC-MS studies revealed the complete structure of the twelve major phytoconstituents that were present in the
leaf extract. In the next stage of the study, the therapeutic effect of the extract as potent anti-bacterial and antifungal
agent has been studied. The presence of a flavonoid and ester groups in the leaf extract as revealed by
the GC-MS analysis and the potential anti-fungal and anti-baterial activity of the extract shows that leaf
extract of Terminalia arjuna has a great potential to be used as a therapeutic agent.
Survival Rate of Metastatic Bone Disease Patients in Haji
Adam Malik Hospital Medan
Authors: Hermantrie Heru , Kadar Pranajaya Dharma , Andriandi  , Lelo Aznan
Published: November 2020

Objective -The aim of this study was to determining the survival rate of patient with
metastatic bone disease in Haji Adam Malik Hospital Medan. Material and Methods-The aim of this
retrospective study is to determine the survival rate of metastatic bone disease patients. Fifty-five
patients who diagnosed of metastatic bone disease during January 2012 – December 2017 were
entered the inclusion criteria were ask and demographic data were also recorded to evaluate further
associated with primary lesion, and surviving status. Survival rate was assessed by Kapplan – Meier
Curve. Results- From January 2012 to December 2017, a total 55 metastatic bone disease patients
were aged 43-77 years. Breast cancer (40%) was the most common primary cancer, with the lowest
survival rate in cervic (10 months). Overall, patients who treat surgically and chemotherapy have
survival rate 17 months. Conclusion-This study revealed that female (33 patients) have 15 months of
survival rate and mael (22 patients) have 18 months of survival rate. Breast was the most common
primary location tumor (40%) and have highest survival rate (20 months). Cervix was the lowest
survival rate (10 months) Overall patients who underwent surgical and chemotherapy have survival
rate in 17 months.
An Efficient Cluster-based Routing Protocol for Improvement Delay in Mobile Ad-hoc Networks
Authors: Najafi Marjan , Soltan Aghaei Mohammad Reza
Published: November 2020

Cluster-based routing in Mobile Ad-Hoc Networks is considered one of the convenient methods of routing. The existence of Cluster Head (CH) in a group of nodes for data forwarding improves the performance of routing in terms of routing overhead and power consumption. In this paper, a clustering algorithm using hierarchical routing for mobile ad hoc networks is proposed. In the proposed method, first, clusters are formed by the FLOC clustering method with low overlapping. Then, according to the most important network criteria, including hop count, noise ratio, distance, remaining energy, and link expiration time, head clusters are selected based on the weighting algorithm. To transfer data in the proposed method, two types of communication are used, e.g., inter-cluster communication and intra-cluster communication in which the shortest path to the target cluster is selected. The proposed P-METHOD technique is based on hierarchy and clustering as well as using a weighted algorithm that reduces delay in data transmission on the network. Moreover, P-METHOD is evaluated here via extensive simulations carried out in NS-2. The simulation results indicate that the MANET network performance metrics are improved in terms of average throughput, Packet Delivery Ratio (PDR), delay, residual energy, and lifetime.
Electrostatic Self-assembly of Composite Nanofiber Yarn
Authors: Wang Wei-Chih , Cheng Yen-Tse , Estroff Benjamin
Published: November 2020

Electrospinning polymer fibers for is a well-understood process, primarily resulting in random mats or single strands. More recent systems and methods have allowed for the production of nanofiber yarns (NFY) for ease of use in textiles. This paper presents a method of NFY manufacture using a simplified dry electrospinning system to produce self-assembling functional NFY capable of conducting electrical charge. The polymer is a mixture of cellulose nanocrystals (CNC), polyvinyl acrylate (PVA) and poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS). When treated with Ethylene Glycol (EG) to enhance conductivity, fibers touching the collector plate align to the applied electrostatic field and grow, twisting together as additional nanofiber polymer is added by the jet. The longer the electrospinning continues, the longer and more uniformly twisted the NFY becomes. This process has the added benefit of reducing the electric field required for NFY production from >2.43 kV cm-1 to 1.875 kV cm-1.
Hypersonic Imaging and Emission Spectroscopy of Hydrogen and Cyanide Following Laser-Induced Optical Breakdown
Authors: Parigger Christian G , Helstern Christopher M , Gautam Ghaneshwar
Published: November 2020

This work communicates the connection of measured shadowgraphs from optically induced air breakdown with emission spectroscopy in selected gas mixtures. Laser-induced optical breakdown is generated using 850 mJ and 170 mJ, 6-ns pulses at a wavelength of 1064 nm, the shadowgraphs are recorded using time-delayed 5-ns pulses at a wavelength of 532 nm and a digital camera, and emission spectra are recorded for typically a dozen of discrete time-delays from optical breakdown by employing an intensified charge-coupled device. The symmetry of the breakdown event can be viewed as close-to spherical symmetry for time-delays of several 100 ns. Spectroscopic analysis explores well-above hypersonic expansion dynamics using primarily the diatomic molecule cyanide and atomic hydrogen emission spectroscopy. Analysis of the air breakdown and selected gas breakdown events permits the use of Abel inversion for inference of the expanding species distribution. Typically, species are prevalent at higher density near the hypersonically expanding shockwave, measured by tracing cyanide and a specific carbon atomic line. Overall, recorded air breakdown shadowgraphs are indicative of laser-plasma expansion in selected gas mixtures, and optical spectroscopy delivers analytical insight into plasma expansion phenomena.
Multiparametric Monitoring of Hypnosis and Nociception-Antinociception Balance During General Anesthesia - A New Era in Patient Safety Standards and Healthcare Management
Authors: Rogobete Alexandru Florin , Bedreag Ovidiu Horea , Papurica Marius , Popovici Sonia Elena , Bratu Lavinia Melania , Rata Andreea , Barsac Claudiu Rafael , Maghiar Andra , Garofil Dragos Nicolae , Negrea Mihai , Petcu Laura Bostangiu , Toma Daiana , Dumbuleu Corina Maria , Rimawi Samir , Sandesc Dorel
Published: November 2020

Worldwide, an increasing number of patients undergo complex surgeries. With the development of general anesthesia techniques and anesthetic substances, the most complex surgical techniques could be developed. In order to adapt the anesthesia according to the particularities of each patient, it is recommended the multimodal monitoring of these patients. Classically, general anesthesia monitoring consists of the analysis of vital functions and gas exchange. Multimodal monitoring refers to the concomitant monitoring of the degree of hypnosis and the nociceptive-antinociceptive balance. By titrating anesthetic drugs according to these parameters, clinical benefits can be obtained, such as hemodynamic stabilization, reduction of awakening times, reduction of post-operative complications. Also, there is an important impact on the status of inflammation and the redox balance. The purpose of this literature review is to present the most modern multimodal monitoring techniques, respectively to discuss the particularities of each technique.
HASTANE İŞ GÜVENLİĞİ UYGULAMALARININ SAĞLIK ÇALIŞANLARININ İŞ GÜVENLİĞİ PERFORMANSINA ETKİSİ
Authors: YILDIZ Ahmet
Published: November 2020

Bu çalışmanın amacı hastane iş güvenliği uygulamalarının sağlık çalışanlarının iş güvenliği performansına etkisini araştırmaktır. Çalışmada ayrıca iş güvenliği performansının çalışanların mesleki ve demografik değişkenlere göre fark gösterip göstermediği de araştırılmıştır. Veri toplama aracı olarak “yönetim taahhüdü”, “güvenlik eğitimi”, “güvenlik iletişimi ve geri bildirim”, “güvenlik kuralları ve prosedürleri” ve “güvenlik tanıtım politikaları” olmak üzere beş boyuttan İş Güvenliği Uygulamaları Ölçeği ve İş Güvenliği Performans Ölçeği kullanılmıştır. Araştırma 232 sağlık çalışanı üzerinde yapılmıştır. Araştırma sonucunda iş güvenliği uygulamaları boyutlarının tümü ile iş güvenliği performansı arasında istatistiksel olarak anlamlı ve pozitif bir ilişkinin olduğu ve iş güvenliği uygulamalarının iş güvenliği performansındaki değişimin %66’ünü açıkladığı görülmüştür. Ayrıca, iş güvenliği performansının yaşça büyük, meslekte çalışma süresi daha fazla ve gündüz görev yapan sağlık çalışanlarının iş güvenliği performanslarının daha yüksek olduğu görülmüştür.
ÖLÇÜSÜZ TURİZM’E (OVER-TOURISM) DAİR KAVRAMSAL BİR YAKLAŞIM
Authors: ÇOLAK Oğuz , KİPER Vahit Oğuz , BATMAN Orhan
Published: November 2020

Kent destinasyonları turizm akımlarının uğrak yeri olması ile birlikte buralarda bazı sorunlar meydana gelmektedir. Bu sorunların önde gelenleri kent destinasyonlarını turistlerin ve yerel halkın paylaşmasından kaynaklanan sorunlardır. Ölçüsüz turizm kavramı, kent destinasyonlarındaki turizm hareketlerinin kabul edilebilir ölçülerin dışına çıkmasını ifade etmektedir. Çalışmanın amacı uluslararası alanyazında “overtourism” olarak kabul görmüş kavramsal ifadenin Türkçe alanyazındaki karşılığının tartışılması ve dünya genelinde ölçüsüz turizm sorunu yaşayan kent destinasyonlarının karşılaştıkları sorunlara ve durumlarına dair genel bir bakış açısı elde etmektir. Çalışmanın amacı doğrultusunda, yorumlayıcı paradigma ekseninde, nitel veri toplama yöntemlerinden arşiv-doküman tarama ve alanyazın incelemesi yöntemleri kullanılmıştır. Elde edilen bulgular, araştırmacılar tarafından betimsel analiz yöntemi ile yorumlanmıştır. Arşiv doküman tarama aşamasında, yurtiçi ve yurtdışı internet bazlı medya-haber kanalları incelenmiş, overtourism sorunu ile ismi anılan kent destinasyonları incelenmiştir. Yine benzer şekilde ilgili uluslararası alanyazın incelenerek, kent destinasyonlarına dair overtourism içerikli araştırmalar incelenmiş ve bazı bulgular elde edilmiş ve yorumlanmıştır. Bu araştırmanın, “ölçüsüz turizm” olarak adlandırılan “overtourism” konusunda genel bir perspektif sunması, bu konudaki bilgileri derlemesi, konunun kavramsal çerçevesinin tartışmaya açılarak daha da netleştirilmesine katkı sunması beklenmektedir.
THE USE OF SOCIAL MEDIA IN BANKS TO ENGENDER WOMEN EMPOWERMENT AND FINANCIAL INCLUSION IN ARAB COUNTRIES
Authors: Yakubi Yusef , Basuki B. , Purwono Rudi
Published: November 2020

This study aims to classify and interpret the interacted communications between banks and users on social media and understand the role of these digital platforms to enhance woman empowerments and financial inclusion in banks in Arab countries. 100 users of banks’ social media were selected from 5 leading banks in 5 Arab countries and their interactive utterances were classified, analyzed and interpreted. Content analysis tools were applied. The study reveals these key results: First, the use of social media in banks entails two-fold empowerment dimensions that are mutually beneficial for Users and Banks. Second, both flows of utterances either from “User to Banks” or “Banks to Users” demonstrate that the highest ratios of the shared content are more closely associated with financial inclusion dimensions than user’s empowerment aspects. Third, women are found more engaged in social and emotional involvements than men who show a relatively higher interest in banks’ financial services and products. It is also found that Banks use social media to raise social and economic themes that support women in the region. However, the second and third results imply a gender gap in financial inclusion since females still lag behind. This study is different by highlighting the power of banks’ social networks to trigger important gender and economic development themes in a highly conservative society and contribute to literature by analyzing and interpreting the shared content from three extensive outlooks which yield ample details and draw implications for banks’ management and social media policy makers and regulators.
FINANCING-TO-VALUE (FTV) POLICY AND ITS IMPACT ON RESIDENTIAL PROPERTY PRICES IN INDONESIA
Authors: Indrawan Imam Wahyudi , Rahman Maya Puspa , Senusi Nurfatihah Ahmad
Published: November 2020

Financing-to-value (FTV) policy is a macroprudential policy currently used by the central banks to maintain the stability of financial systems and prevent systemic risks. In Indonesia this is particularly the case in relation to financing of the property sector by Islamic financial institutions. This paper aims to analyse the impact of FTV policy on the residential property price index (RPPI) in Indonesia using a panel data analysis method. Indonesia is chosen in this study as it is one of the countries implementing FTV policy in its Islamic banking system. There are three important findings to be drawn from the study. First, FTV policy ratios significantly affect RPPI.
ISLAMIC BANKING AND BANK PERFORMANCE IN MALAYSIA: AN EMPIRICAL ANALYSIS
Authors: Ibrahim Mansor
Published: November 2020

This paper examines the performance of Malaysia’s banking sector and its relationship to the presence of Islamic banking in the country. More specifically, by controlling for the theoretically relevant determinants of bank performance we compare the efficiency, profitability and risk of Islamic banks to conventional banks and examine the spillover effects of Islamic banking penetration on bank performance. To these ends, we adopt a panel modelling approach. Taking note that our focal variables comprise the time-invariant Islamic banking dummy and potentially endogenous Islamic banking share, we apply the Hausman–Taylor (HT) instrumental-variable estimator in the analysis. Our results indicate that Islamic banks in Malaysia are less profitable than their conventional counterparts and that Islamic banking penetration is associated with lower bank profitability. However, the increasing presence of Islamic banking appears to make Malaysian banks less risky and, with limited evidence, more efficient. Finally, the efficiency–risk trade-off seems to have potential as the Islamic banking portion of the sector increases in size. These results are reasonably robust compared to alternative specifications of the model.
Artificial intelligence predicts the immunogenic landscape of SARS-CoV-2: toward universal blueprints for vaccine designs
Authors: Malone Brandon , Simovski Boris , Moliné Clément , Cheng Jun , Gheorghe Marius , Fontenelle Hugues , Vardaxis Ioannis , Tennøe Simen , Malmberg Jenny-Ann , Stratford Richard , Clancy Trevor
Published: November 2020

This protocol predicts blueprints for vaccine design that contain a broad repertoire of T-cell epitopes optimized for the global population. The protocol first requires a screening of the SARS-CoV-2 proteome using immunogenicity predictors to generate comprehensive epitope maps. Then, these epitope maps are used as input to Monte Carlo simulations designed to identify statistically significant “epitope hotspot” regions in the virus that are most likely to be immunogenic. The epitope hotspots that share significant homology with proteins in the human proteome are removed to reduce the chance of inducing off-target autoimmune responses. Finally, a database of the actual HLA genotypes of citizens is used to develop a “digital twin” type simulation to model how effective different combinations of hotspots would work in a diverse human population. The approach identifies an optimal constellation of epitope hotspots that could provide maximum coverage in the human population.