bluuebunny/crossref_metadata_2025 huggingface dataset:
Behavioral changes during the COVID-19 pandemic decreased income diversity of urban encounters
Authors: Yabe Takahiro , Bueno Bernardo García Bulle , Dong Xiaowen , Pentland Alex , Moro Esteban
Published: April 2023

Diversity of physical encounters in urban environments is known to spur economic productivity while also fostering social capital. However, mobility restrictions during the pandemic have forced people to reduce urban encounters, raising questions about the social implications of behavioral changes. In this paper, we study how individual income diversity of urban encounters changed during the pandemic, using a large-scale, privacy-enhanced mobility dataset of more than one million anonymized mobile phone users in Boston, Dallas, Los Angeles, and Seattle, across three years spanning before and during the pandemic. We find that the diversity of urban encounters has substantially decreased (by 15% to 30%) during the pandemic and has persisted through late 2021, even though aggregated mobility metrics have recovered to pre-pandemic levels. Counterfactual analyses show that behavioral changes including lower willingness to explore new places further decreased the diversity of encounters in the long term. Our findings provide implications for managing the trade-off between the stringency of COVID-19 policies and the diversity of urban encounters as we move beyond the pandemic.
Bioinspired soft robots based on organic polymer-crystal hybrid materials with response to temperature and humidity
Authors: Yang Xuesong , Lan Linfeng , Pan Xiuhong , Di Qi , Liu Xiaokong , Li Liang , Naumov Panče , Zhang Hongyu
Published: April 2023

The capability of stimulated response by mechanical deformation to induce motion or actuation is the foundation of lightweight organic, dynamic materials for designing light and soft robots. Various biomimetic soft robots are constructed to demonstrate the vast versatility of responses and flexibility in shape-shifting. We now report that the integration of organic molecular crystals and polymers brings about synergistic improvement in the performance of both materials as a hybrid materials class, with the polymers adding hygroresponsive and thermally responsive functionalities to the crystals. The resulting hybrid dynamic elements respond within milliseconds, which represents several orders of magnitude of improvement in the time response relative to some other type of common actuators. Combining molecular crystals with polymers brings crystals as largely overlooked materials much closer to specific applications in soft (micro)robotics and related fields.
Tetrachromatic vision-inspired neuromorphic sensors with ultraweak ultraviolet detection
Authors: Jiang Ting , Wang Yiru , Zheng Yingshuang , Wang Le , He Xiang , Li Liqiang , Deng Yunfeng , Dong Huanli , Tian Hongkun , Geng Yanhou , Xie Linghai , Lei Yong , Ling Haifeng , Ji Deyang , Hu Wenping
Published: April 2023

Sensing and recognizing invisible ultraviolet (UV) light is vital for exploiting advanced artificial visual perception system. However, due to the uncertainty of the natural environment, the UV signal is very hard to be detected and perceived. Here, inspired by the tetrachromatic visual system, we report a controllable UV-ultrasensitive neuromorphic vision sensor (NeuVS) that uses organic phototransistors (OPTs) as the working unit to integrate sensing, memory and processing functions. Benefiting from asymmetric molecular structure and unique UV absorption of the active layer, the as fabricated UV-ultrasensitive NeuVS can detect 370 nm UV-light with the illumination intensity as low as 31 nW cm−2, exhibiting one of the best optical figures of merit in UV-sensitive neuromorphic vision sensors. Furthermore, the NeuVS array exbibits good image sensing and memorization capability due to its ultrasensitive optical detection and large density of charge trapping states. In addition, the wavelength-selective response and multi-level optical memory properties are utilized to construct an artificial neural network for extract and identify the invisible UV information. The NeuVS array can perform static and dynamic image recognition from the original color image by filtering red, green and blue noise, and significantly improve the recognition accuracy from 46 to 90%.
Unsupervised approach to decomposing neural tuning variability
Authors: Zhu Rong J. B. , Wei Xue-Xin
Published: April 2023

Neural representation is often described by the tuning curves of individual neurons with respect to certain stimulus variables. Despite this tradition, it has become increasingly clear that neural tuning can vary substantially in accordance with a collection of internal and external factors. A challenge we are facing is the lack of appropriate methods to accurately capture the moment-to-moment tuning variability directly from the noisy neural responses. Here we introduce an unsupervised statistical approach, Poisson functional principal component analysis (Pf-PCA), which identifies different sources of systematic tuning fluctuations, moreover encompassing several current models (e.g.,multiplicative gain models) as special cases. Applying this method to neural data recorded from macaque primary visual cortex– a paradigmatic case for which the tuning curve approach has been scientifically essential– we discovered a simple relationship governing the variability of orientation tuning, which unifies different types of gain changes proposed previously. By decomposing the neural tuning variability into interpretable components, our method enables discovery of unexpected structure of the neural code, capturing the influence of the external stimulus drive and internal states simultaneously.
Rapid determination of solid-state diffusion coefficients in Li-based batteries via intermittent current interruption method
Authors: Chien Yu-Chuan , Liu Haidong , Menon Ashok S. , Brant William R. , Brandell Daniel , Lacey Matthew J.
Published: April 2023

The galvanostatic intermittent titration technique (GITT) is considered the go-to method for determining the Li+ diffusion coefficients in insertion electrode materials. However, GITT-based methods are either time-consuming, prone to analysis pitfalls or require sophisticated interpretation models. Here, we propose the intermittent current interruption (ICI) method as a reliable, accurate and faster alternative to GITT-based methods. Using Fick’s laws, we prove that the ICI method renders the same information as the GITT within a certain duration of time since the current interruption. Via experimental measurements, we also demonstrate that the results from ICI and GITT methods match where the assumption of semi-infinite diffusion applies. Moreover, the benefit of the non-disruptive ICI method to operando materials characterization is exhibited by correlating the continuously monitored diffusion coefficient of Li+ in a LiNi0.8Mn0.1Co0.1O2-based electrode to its structural changes captured by operando X-ray diffraction measurements.
RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells
Authors: Herrejon Chavez Florisela , Luo Hanzhi , Cifani Paolo , Pine Alli , Chu Eren L. , Joshi Suhasini , Barin Ersilia , Schurer Alexandra , Chan Mandy , Chang Kathryn , Han Grace Y. Q. , Pierson Aspen J. , Xiao Michael , Yang Xuejing , Kuehm Lindsey M. , Hong Yuning , Nguyen Diu T. T. , Chiosis Gabriela , Kentsis Alex , Leslie Christina , Vu Ly P. , Kharas Michael G.
Published: April 2023

Tissue homeostasis is maintained after stress by engaging and activating the hematopoietic stem and progenitor compartments in the blood. Hematopoietic stem cells (HSCs) are essential for long-term repopulation after secondary transplantation. Here, using a conditional knockout mouse model, we revealed that the RNA-binding protein SYNCRIP is required for maintenance of blood homeostasis especially after regenerative stress due to defects in HSCs and progenitors. Mechanistically, we find that SYNCRIP loss results in a failure to maintain proteome homeostasis that is essential for HSC maintenance. SYNCRIP depletion results in increased protein synthesis, a dysregulated epichaperome, an accumulation of misfolded proteins and induces endoplasmic reticulum stress. Additionally, we find that SYNCRIP is required for translation of CDC42 RHO-GTPase, and loss of SYNCRIP results in defects in polarity, asymmetric segregation, and dilution of unfolded proteins. Forced expression of CDC42 recovers polarity and in vitro replating activities of HSCs. Taken together, we uncovered a post-transcriptional regulatory program that safeguards HSC self-renewal capacity and blood homeostasis.
Cross-stage neural pattern similarity in the hippocampus predicts false memory derived from post-event inaccurate information
Authors: Shao Xuhao , Li Ao , Chen Chuansheng , Loftus Elizabeth F. , Zhu Bi
Published: April 2023

The misinformation effect occurs when people’s memory of an event is altered by subsequent inaccurate information. No study has systematically tested theories about the dynamics of human hippocampal representations during the three stages of misinformation-induced false memory. This study replicates behavioral results of the misinformation effect, and investigates the cross-stage pattern similarity in the hippocampus and cortex using functional magnetic resonance imaging. Results show item-specific hippocampal pattern similarity between original-event and post-event stages. During the memory-test stage, hippocampal representations of original information are weakened for true memory, whereas hippocampal representations of misinformation compete with original information to create false memory. When false memory occurs, this conflict is resolved by the lateral prefrontal cortex. Individuals’ memory traces of post-event information in the hippocampus predict false memory, whereas original information in the lateral parietal cortex predicts true memory. These findings support the multiple-trace model, and emphasize the reconstructive nature of human memory.
Building electrode skins for ultra-stable potassium metal batteries
Authors: Ding Hongbo , Wang Jue , Zhou Jiang , Wang Chengxin , Lu Bingan
Published: April 2023

In nature, the human body is a perfect self-organizing and self-repairing system, with the skin protecting the internal organs and tissues from external damages. In this work, inspired by the human skin, we design a metal electrode skin (MES) to protect the metal interface. MES can increase the flatness of electrode and uniform the electric field distribution, inhibiting the growth of dendrites. In detail, an artificial film made of fluorinated graphene oxide serves as the first protection layer. At molecular level, fluorine is released and in-situ formed a robust SEI as the second protection “skin” for metal anode. As a result, Cu@MES | | K asymmetric cell is able to achieve an unprecedented cycle life (over 1600 cycles). More impressively, the full cell of K@MES | | Prussian blue exhibits a long cycle lifespan over 5000 cycles. This work illustrates a mechanism for metal electrode protection and provides a strategy for the applying bionics in batteries.
Transcriptomics unravels molecular changes associated with cilia and COVID-19 in chronic rhinosinusitis with nasal polyps
Authors: Torinsson Naluai Åsa , Östensson Malin , Fowler Philippa C. , Abrahamsson Sanna , Andersson Björn , Lassesson Stina , Jacobsson Frida , Oscarsson Martin , Bohman Anton , Harandi Ali M. , Bende Mats
Published: April 2023

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common upper respiratory tract complication where the pathogenesis is largely unknown. Herein, we investigated the transcriptome profile in nasal mucosa biopsies of CRSwNP patients and healthy individuals. We further integrated the transcriptomics data with genes located in chromosomal regions containing genome-wide significant gene variants for COVID-19. Among the most significantly upregulated genes in polyp mucosa were CCL18, CLEC4G, CCL13 and SLC9A3. Pathways involving “Ciliated epithelial cells” were the most differentially expressed molecular pathways when polyp mucosa and non-polyp mucosa from the same patient was compared. Natural killer T-cell (NKT) and viral pathways were the most statistically significant pathways in the mucosa of CRSwNP patients compared with those of healthy control individuals. Upregulated genes in polyp mucosa, located within the genome-wide associated regions of COVID-19, included LZTFL1, CCR9, SLC6A20, IFNAR1, IFNAR2 and IL10RB. Interestingly, the second most over-expressed gene in our study, CLEC4G, has been shown to bind directly to SARS-CoV-2 spike's N-terminal domain and mediate its entry and infection. Our results on altered expression of genes related to cilia and viruses point to the de-regulation of viral defenses in CRSwNP patients, and may give clues to future intervention strategies.
Coal-gangue recognition via multi-branch convolutional neural network based on MFCC in noisy environment
Authors: Jiang HaiYan , Zong DaShuai , Song QingJun , Gao KuiDong , Shao HuiZhi , Liu ZhiJiang , Tian Jing
Published: April 2023

Traditional coal-gangue recognition methods usually do not consider the impact of equipment noise, which severely limits its adaptability and recognition accuracy. This paper mainly studies the more accurate recognition of coal-gangue in the noise site environment with the operation of shearer, conveyor, transfer machine and other device in the process of top coal caving. Mel Frequency Cepstrum Coefficients (MFCC) smoothing method was introduced to express the intrinsic feature of sound pressure more clearly in the coal-gangue recognition site. Then, a multi-branch convolution neural network (MBCNN) model with three branches was developed, and the smoothed MFCC feature was incorporated into this model to realize the recognition of falling coal and gangue in noisy environment. The sound pressure signal datasets under the operation of different device were constructed through a great deal of laboratory and site data acquisition. Comparative experiments were carried out on noiseless dataset, single noise dataset and simulated site dataset, and the results show that our method can provide higher correct recognition accuracy and better robustness. The proposed coal-gangue recognition approach based on MBCNN and MFCC smoothing can not only recognize the state of falling coal or gangue, but also recognize the operational state of site device.
Evaluating the impact of first-yes-counts instructions on eyewitness performance using the two-high threshold eyewitness identification model
Authors: Winter Kristina , Menne Nicola Marie , Bell Raoul , Buchner Axel
Published: April 2023

In eyewitness research, multiple identification decisions in sequential lineups are typically prevented by telling participants that only their first identification decision counts. These first-yes-counts instructions are incompatible with standard police protocols prescribing that witnesses shall see the entire lineup. Horry et al. were the first to experimentally test how this discrepancy between eyewitness research and standard police protocols affects eyewitness identification decisions. Here, the two-high threshold eyewitness identification model was used to disentangle the effect of the first-yes-counts instructions on the detection and guessing processes underlying eyewitness identification decisions. We report both a reanalysis of Horry et al.’s data and a conceptual replication. Both the reanalysis and the results of the conceptual replication confirm that first-yes-counts instructions do not affect the detection of the culprit but decrease the probability of guessing-based selections. To improve the ecological validity, research on sequential lineups should avoid first-yes-counts instructions.
Extended perceptive field revealed in humans with binocular fusion disorders
Authors: Benhaim-Sitbon Laura , Lev Maria , Polat Uri
Published: April 2023

Binocular vision disorders or dysfunctions have considerable impact on daily visual activities such as reading. Heterophoria (phoria) is a latent eye misalignment (with a prevalence of up to 35%) that appears in conditions that disrupt binocular vision and it may affect the quality of binocular fusion. Our recent study, which used lateral masking (LM), suggests that subjects with binocular fusion disorders (horizontal phoria) exhibit an asymmetry and an abnormal pattern of both binocular and monocular lateral interactions, but only for the horizontal meridian (HM). The perceptive field (PF) is the fundamental processing unit of human vision and both masking and crowding depend on its size. An increased PF size is found in amblyopic populations or in young children. We hypothesized that the PF’s size would be asymmetric only for the phoric group (larger along the HM). We estimated the PF’s size using two different methods (LM with equal-phase and opposite-phase flankers). Phoric subjects exhibited a larger binocular PF size, only for the HM, confirming our hypothesis of an asymmetric PF size. However, the monocular PF size of phoric and control subjects was similar. Phoria affects the PF’s size similarly to meridional amblyopia but without being attributed to abnormal refraction. We suggest that these findings could help explain the inter-observer variability found in the masking literature and the reading difficulties often encountered in subjects with high heterophoria. Since perceptual learning can reduce the PF’s size, further investigation of training may provide a novel therapy to reduce some symptoms related to heterophoria.
Modelling of icodextrin hydrolysis and kinetics during peritoneal dialysis
Authors: Stachowska-Pietka Joanna , Waniewski Jacek , Olszowska Anna , Garcia-Lopez Elvia , Wankowicz Zofia , Lindholm Bengt
Published: April 2023

In peritoneal dialysis, ultrafiltration is achieved by adding an osmotic agent into the dialysis fluid. During an exchange with icodextrin-based solution, polysaccharide chains are degraded by α-amylase activity in dialysate, influencing its osmotic properties. We modelled water and solute removal taking into account degradation by α-amylase and absorption of icodextrin from the peritoneal cavity. Data from 16 h dwells with icodextrin-based solution in 11 patients (3 icodextrin-exposed, 8 icodextrin-naïve at the start of the study) on dialysate volume, dialysate concentrations of glucose, urea, creatinine and α-amylase, and dialysate and blood concentrations of seven molecular weight fractions of icodextrin were analysed. The three-pore model was extended to describe hydrolysis of icodextrin by α-amylase. The extended model accurately predicted kinetics of ultrafiltration, small solutes and icodextrin fractions in dialysate, indicating differences in degradation kinetics between icodextrin-naïve and icodextrin-exposed patients. In addition, the model provided information on the patterns of icodextrin degradation caused by α-amylase. Modelling of icodextrin kinetics using an extended three-pore model that takes into account absorption of icodextrin and changes in α-amylase activity in the dialysate provided accurate description of peritoneal transport and information on patterns of icodextrin hydrolysis during long icodextrin dwells.
Startle-triggered responses indicate reticulospinal drive is larger for voluntary shoulder versus finger movements
Authors: Maslovat Dana , Santangelo Cassandra M. , Carlsen Anthony N.
Published: April 2023

Recent primate studies have implicated a substantial role of reticulospinal pathways in the production of various voluntary movements. A novel way to assess the relative reticulospinal contributions in humans is through the use of a “StartReact” paradigm where a startling acoustic stimulus (SAS) is presented during a simple reaction time (RT) task. The StartReact response is characterized by short-latency triggering of a prepared response, which is attributed to increased reticulospinal drive associated with startle reflex activation. The current study used a StartReact protocol to examine differences in reticulospinal contributions between proximal and distal effectors by examining EMG onset latencies in lateral deltoid and first dorsal interosseous during bilateral shoulder or finger abduction. The magnitude of the StartReact effect, and thus relative reticulospinal drive, was quantified as the difference in RT between startle trials in which startle-reflex related EMG activation in the sternocleidomastoid (SCM) was present (SCM +) versus absent (SCM −). A significantly larger StartReact effect was observed for bilateral shoulder abduction versus bimanual finger abduction and a higher incidence of SCM + trials occurred in the proximal task. Additionally, both startle reflex and response-related EMG measures were larger on SCM + trials for the shoulder versus finger task. These results provide compelling novel evidence for increased reticulospinal activation in bilateral proximal upper-limb movements.
A mathematical modeling technique to understand the role of decoy receptors in ligand-receptor interaction
Authors: Dey Subrata , Ghosh Aditi , Banerjee Malay
Published: April 2023

The ligand-receptor interaction is fundamental to many cellular processes in eukaryotic cells such as cell migration, proliferation, adhesion, signaling and so on. Cell migration is a central process in the development of organisms. Receptor induced chemo-tactic sensitivity plays an important role in cell migration. However, recently some receptors identified as decoy receptors, obstruct some mechanisms of certain regular receptors. DcR3 is one such important decoy receptor, generally found in glioma cell, RCC cell and many various malignant cells which obstruct some mechanism including apoptosis cell-signaling, cell inflammation, cell migration. The goal of our work is to mathematically formulate ligand-receptor interaction induced cell migration in the presence of decoy receptors. We develop here a novel mathematical model, consisting of four coupled partial differential equations which predict the movement of glioma cells due to the reaction-kinetic mechanism between regular receptors CD95, its ligand CD95L and decoy receptors DcR3 as obtained in experimental results. The aim is to measure the number of cells in the chamber’s filter for different concentrations of ligand in presence of decoy receptors and compute the distance travelled by the cells inside filter due to cell migration. Using experimental results, we validate our model which suggests that the concentration of ligands plays an important role in cell migration.
Feasibility of in vivo multi-parametric quantitative magnetic resonance imaging of the healthy sciatic nerve with a unified signal readout protocol
Authors: Boonsuth Ratthaporn , Battiston Marco , Grussu Francesco , Samlidou Christina Maria , Calvi Alberto , Samson Rebecca S. , Gandini Wheeler-Kingshott Claudia A. M. , Yiannakas Marios C.
Published: April 2023

Magnetic resonance neurography (MRN) has been used successfully over the years to investigate the peripheral nervous system (PNS) because it allows early detection and precise localisation of neural tissue damage. However, studies demonstrating the feasibility of combining MRN with multi-parametric quantitative magnetic resonance imaging (qMRI) methods, which provide more specific information related to nerve tissue composition and microstructural organisation, can be invaluable. The translation of emerging qMRI methods previously validated in the central nervous system to the PNS offers real potential to characterise in patients in vivo the underlying pathophysiological mechanisms involved in a plethora of conditions of the PNS. The aim of this study was to assess the feasibility of combining MRN with qMRI to measure diffusion, magnetisation transfer and relaxation properties of the healthy sciatic nerve in vivo using a unified signal readout protocol. The reproducibility of the multi-parametric qMRI protocol as well as normative qMRI measures in the healthy sciatic nerve are reported. The findings presented herein pave the way to the practical implementation of joint MRN-qMRI in future studies of pathological conditions affecting the PNS.
Role of DNA methylation in the relationship between glioma risk factors and glioma incidence: a two-step Mendelian randomization study
Authors: Howell Amy E. , Relton Caroline , Martin Richard M. , Zheng Jie , Kurian Kathreena M.
Published: April 2023

Genetic evidence suggests glioma risk is altered by leukocyte telomere length, allergic disease (asthma, hay fever or eczema), alcohol consumption, childhood obesity, low-density lipoprotein cholesterol (LDLc) and triglyceride levels. DNA methylation (DNAm) variation influences many of these glioma-related traits and is an established feature of glioma. Yet the causal relationship between DNAm variation with both glioma incidence and glioma risk factors is unknown. We applied a two-step Mendelian randomization (MR) approach and several sensitivity analyses (including colocalization and Steiger filtering) to assess the association of DNAm with glioma risk factors and glioma incidence. We used data from a recently published catalogue of germline genetic variants robustly associated with DNAm variation in blood (32,851 participants) and data from a genome-wide association study of glioma risk (12,488 cases and 18,169 controls, sub-divided into 6191 glioblastoma cases and 6305 non-glioblastoma cases). MR evidence indicated that DNAm at 3 CpG sites (cg01561092, cg05926943, cg01584448) in one genomic region (HEATR3) had a putative association with glioma and glioblastoma risk (False discovery rate [FDR] < 0.05). Steiger filtering provided evidence against reverse causation. Colocalization presented evidence against genetic confounding and suggested that differential DNAm at the 3 CpG sites and glioma were driven by the same genetic variant. MR provided little evidence to suggest that DNAm acts as a mediator on the causal pathway between risk factors previously examined and glioma onset. To our knowledge, this is the first study to use MR to appraise the causal link of DNAm with glioma risk factors and glioma onset. Subsequent analyses are required to improve the robustness of our results and rule out horizontal pleiotropy.
Association of lipid composition and unsaturated fatty acids of VLDL with atrial remodeling in metabolic syndrome
Authors: Lee Hsiang-Chun , Cheng Wei-Chung , Ma Wen-Lung , Lin Yu-Hsun , Shin Shyi-Jang , Lin Yi-Hsiung
Published: April 2023

Subjects with metabolic syndrome (MetS) commonly have atrial remodeling, which indicates a risk for atrial fibrillation. This study determined MetS-related changes in lipid components in very-low-density lipoprotein (VLDL), which has been shown to cause atrial remodeling, the effect of statins on these changes, and the correlation between atrial remodeling and VLDL lipid compositions. Blood samples were collected from 12 non-MetS and 27 sex- and age-matched MetS subjects. Fourteen patients with MetS (MetS-off statin) discontinued statin therapy 14 days before the study, while the remaining 13 remained on it (MetS-on statin). The VLDLs were isolated and processed for mass-based lipid profiling. Lipidomic analyses were performed and associated with atrial remodeling markers measured using standard echocardiography and electrocardiography. Compared with the VLDL components of the non-MetS group, glucosyl/galactosyl ceramide, lyso-phosphatidylcholine, lyso-phosphatidylethanolamine, and triglycerides were enriched in the MetS-off statin group. Statin therapy attenuated all abnormally abundant lipid classes in MetS, except for triglycerides. In addition, lyso-phosphatidylcholine, lyso-phosphatidylethanolamine, and triglycerides were significantly correlated with atrial dilatation, and the latter two were also correlated with the PR interval. Enrichment of double bonds, which indicate unsaturated fatty acids, was also significantly correlated with atrial remodeling and P-wave duration. This study suggests that the pathological lipid payload of MetS-VLDL may contribute to atrial remodeling in patients.
Evaluation of the impact of Covid-19 on air traffic volume in Turkish airspace using artificial neural networks and time series
Authors: Gultekin Nurullah , Acik Kemaloglu Sibel
Published: April 2023

In early 2020, the aviation sector was one of the business lines adversely affected by the Covid 19 outbreak that affected the whole world. As a result, some countries imposed travel restrictions. Following these restrictions, air traffic density has decreased significantly worldwide. Since air traffic density directly affects almost all operations in air transportation, analyzing these data is very essential. For this purpose, SARIMA models, one of the linear time series models, and multilayer perceptron model (MLP), one of the artificial neural network methods suitable for nonlinear modeling, were applied to the air traffic data regarding Turkish airspace between 2010 and 2019, and the actual air traffic density was compared with the forecasts obtained from these analyses. It is considered that the results of this study are essential for organizations conducting aviation operations to take into consideration while doing future planning.
Prediction of ground vibration due to mine blasting in a surface lead–zinc mine using machine learning ensemble techniques
Authors: Hosseini Shahab , Pourmirzaee Rashed , Armaghani Danial Jahed , Sabri Sabri Mohanad Muayad
Published: April 2023

Ground vibration due to blasting is identified as a challenging issue in mining and civil activities. Peak particle velocity (PPV) is one of the blasting undesirable consequences, which is resulted during emission of vibration in blasted bench. This study focuses on the PPV prediction in the surface mines. In this regard, two ensemble systems, i.e., the ensemble of artificial neural networks and the ensemble of extreme gradient boosting (EXGBoosts) were developed for PPV prediction in one of the largest lead–zinc open-pit mines in the Middle East. For ensemble modeling, several ANN and XGBoost base models were separately designed with different architectures. Then, the validation indices such as coefficient determination (R2), root mean square error (RMSE), mean absolute error (MAE), the variance accounted for (VAF), and Accuracy were used to evaluate the performance of the base models. The five top base models with high accuracy were selected to construct an ensemble model for each of the methods, i.e., ANNs and XGBoosts. To combine the outputs of the top base models and achieve a single result stacked generalization technique, was employed. Findings showed ensemble models increase the accuracy of PPV predicting in comparison with the best individual models. The EXGBoosts was superior method for predicting of the PPV, which obtained values of R2, RMSE, MAE, VAF, and Accuracy corresponding to the EXGBoosts were (0.990, 0.391, 0.257, 99.013(%), 98.216), and (0.968, 0.295, 0.427, 96.674(%), 96.059), for training and testing datasets, respectively. However, the sensitivity analysis indicated that the spacing (r = 0.917) and number of blast-holes (r = 0.839) had the highest and lowest impact on the PPV intensity, respectively.
Single-atomic rhenium-assisted 2H-to-1T phase transformation of MoS2 nanosheets boosting electrocatalytic hydrogen evolution
Authors: Yu Jianmin , Qian Yongteng , Wang Qing , Su Chenliang , Lee Hyoyoung , Shang Lu , Zhang Tierui
Published: April 2023

Single-atomic Re on 1T-2H MoS2 heterostructure demonstrates HER performance on par with Pt/C electrocatalyst. This good performance is attributed to the introduction of Re single atoms that promote phase transition and serve as active sites for water dissociation.
Local phonon imaging of AlN nanostructures with nanoscale spatial resolution
Authors: Milekhin Ilya , Anikin Kirill , Kurus Nina N. , Mansurov Vladimir G. , Malin Timur V. , Zhuravlev Konstantin S. , Milekhin Alexander G. , Latyshev Alexander V. , Zahn Dietrich R. T.
Published: April 2023

We demonstrate local phonon analysis of single AlN nanocrystals by two complementary imaging spectroscopic techniques: tip-enhanced Raman scattering (TERS) and nano-Fourier transform infrared (nano-FTIR) spectroscopy.
Recent developments in the UV-visible light-intervened ring-opening polymerization of cyclic esters
Authors: Yadav Neeraj , Chundawat Tejpal Singh
Published: April 2023

Synthesis of biodegradable polyesters using the photoinduced ring-opening polymerization (photoROP) technique in the presence of photoacid generators (PAGs) and photobase generators (PBGs) as catalysts.
In situ FTIR study of 2D-carbon materials for CO2 splitting under non-thermal plasma environment – selective CO production
Authors: Wiśniewski Marek , Liu Xinying
Published: April 2023

Carbon dioxide conversion has been considered a promising solution to global warming and as a source of CO.
Heat and osmosis cooperatively driven power generation in robust two-dimensional hybrid nanofluidic channels
Authors: Xiao Tianliang , Li Xuejiang , Liu Zhaoyue , Lu Bingxin , Zhai Jin , Diao Xungang
Published: April 2023

Heat and osmosis cooperatively driven power generation in robust two-dimensional hybrid nanofluidic channels is shown.
Recent advances in natural small molecules as drug delivery systems
Authors: Fu Shiyao , Yang Xin
Published: April 2023

Natural small molecules (NSMs) with anticancer activity and assembly functions show great potential as novel DDSs in the biomedical field. In this review, we provide an overview of the assembly mechanism of NSMs and their application in DDSs.
Enabling enhanced lithium storage capacity of two-dimensional pentagonal BN2 by aluminum doping
Authors: Thanasarnsurapong Thanasee , Detrattanawichai Panyalak , Dabsamut Klichchupong , Simalaotao Kodchakorn , Maluangnont Tosapol , Boonchun Adisak
Published: April 2023

The highest theoretical Li storage capacity (2297 mA h g−1) to date in a pentagonal structure, achieved through aluminum-for-boron substitution in penta-BN2.
Photon-driven bactericidal performance of surface-modified TiO2 nanofibers
Authors: Shahriari-Khalaji Mina , Zabihi Fatemeh , Bahi Addie , Sredojević Dušan , Nedeljković Jovan M. , Macharia Daniel K. , Ciprian Matteo , Yang Shengyuan , Ko Frank
Published: April 2023

Visible-light-responsive graphite-embedded titanium dioxide nanofibers (G-TiO2 NFs), prepared by electrospinning and post-treatment with rhodizonic acid (RhA), show biocidal effects against E. coli and S. aureus when excited with visible light.
Radiosensitising effect of iron oxide‐gold nanocomplex for electron beam therapy of melanoma in vivo by magnetic targeting
Authors: Mohamadkazem Mahshad , Neshastehriz Ali , Amini Seyed Mohammad , Moshiri Ali , Janzadeh Atousa
Published: April 2023

Melanoma is a dangerous type of skin cancer sometimes treated with radiotherapy. However, it induces damage to the surrounding healthy tissue and possibly further away areas. Therefore, it is necessary to give a lower dose to the patient with targeted therapy. In this study, the radio‐sensitising effect of gold‐coated iron oxide nanoparticles on electron beam radiotherapy of a melanoma tumour with magnetic targeting in a mouse model was investigated. Gold‐coated iron oxide nanoparticles were prepared in a steady procedure. The melanoma tumour model was induced in mice. Animals were divided into five groups: (1) normal; (2) melanoma; (3) gold‐coated iron oxide nanoparticles alone; (4) electron beam radiotherapy; (5) electron beam radiotherapy plus gold‐coated iron oxide nanoparticles. The magnet was placed on the tumour site for 2 h. The tumours were then exposed to 6 MeV electron beam radiotherapy for a dose of 8 Gy. Inductively coupled plasma optical emission spectrometry test, hematoxylin and eosin staining, and enzyme‐linked immunosorbent assay blood test were also performed. Gold‐coated iron oxide nanoparticles with magnetic targeting before electron beam radiotherapy reduced the growth of the tumour compared to the control group. Blood tests did not show any significant toxicity. Deposition of nanoparticles was more in the tumour and spleen tissue and to a lesser extent in the liver, kidney, and lung tissues. The synergistic effect of nanoparticles administered by the intraperitoneal route and then concentrated into the tumour area by application of an external permanent magnet, before delivery of the electron beam radiotherapy improved the overall cancer treatment outcome and prevented metal distribution side effects.
Avancées sur le multirecyclage en réacteur à eau pressurisée
Authors: Evans Cécile , Laugier Frédéric , Louf Pierre-Henri , Rugama Yolanda , Sudreau François , Vaast Guillaume
Published: April 2023

Le programme de R&D français sur le Multirecyclage en REP (MRREP) est un cycle de transition préparant la fermeture du cycle avec le déploiement des Réacteurs à neutrons rapides (RNR). Il permettra de stabiliser les inventaires de combustibles usés et le plutonium dans les entreposages et d’augmenter significativement la part des matières recyclées utilisées dans les réacteurs français.
“La politique française en matière de gestion des déchets radioactifs est solide”
Authors: Abadie Pierre-Marie , Dupin Ludovic
Published: April 2023

L’Agence nationale de gestion des déchets radioactifs (Andra) a déposé, le 16 janvier dernier, la demande d’autorisation de création (DAC) du site de stockage géologique Cigéo. Son directeur général, Pierre-Marie Abadie, revient sur ce chantier majeur et détaille les travaux de l’agence dans le cadre de sa feuille de route 2026.
Advanced Fuel Management : le combustible enrichi de Framatome pour accroître les performances des réacteurs aux États-Unis
Authors: Cole Steven , Garner Norman , Bolsée Gwen
Published: April 2023

Aux États-Unis, un programme consistant à utiliser de l’uranium plus enrichi dans les réacteurs afin d’améliorer leur performance et leur disponibilité est en cours. Framatome est au cœur du dispositif pour la conception du combustible et son transport.
Exploration of the integration of Civic Politics elements in the course of “Electronic Cognitive Practice”
Authors: Li Biqing , Gao Yubo , Li Yuming , Li Jiaying , Zheng Shiyong
Published: April 2023

Practical courses are an integral part of the training program of undergraduate majors and occupy an important position and value in the talent training system, which has high requirements for the introduction of the course Civics. This paper takes the practical course of “Electronic Cognitive Practice” as an example, and discusses the integration of thought politics elements into practical courses from multiple perspectives, such as course reconstruction, clarification of course objectives, adjustment of teaching contents, reform of teaching methods, innovation of assessment contents and methods, and improvement of teachers’ thought politics ability, so as to make the classroom teaching of practical courses organically integrated with thought politics education and thus realize the “thought politics in practical courses”. This will enable the classroom teaching of the practical courses to be organically integrated with the thinking and politics education, thus realizing the “thinking and politics in the courses, and the courses integrating thinking and politics” of the practical courses.
Research on deepening the education of ideals and beliefs in rural free orientation medical students’ employment guidance courses
Authors: Pang Jingshai , Li Haili , Bai Guifeng
Published: April 2023

Under the background of implementing the strategy of healthy China and rural revitalization in the new era, the education and management of free oriented medical students in rural areas has been paid more and more attention. The employment guidance courses for free orientation students in rural areas are becoming more and more standardized, and the class schedule has been developed from scratch, but the course design, especially the interaction between teachers and students during online teaching, is not sufficient. The conclusion of the study is that the free orientation medical students’ employment guidance courses in rural areas should strengthen the ideal and belief education modules, tailor-made career planning, and use experiential teaching methods to train students to grow up to be good at treating minor diseases, being good at treating serious diseases, being good at managing chronic diseases, Qualified grassroots general practitioners who turn from acute illness to improvement.
Ideological and political study of college English courses under the guidance of ecological linguistics
Authors: Wang Fei
Published: April 2023

With the development of The Times, the new curriculum reform is gradually promoted. Ideological and political course has become the key teaching goal in the current university curriculum, and also the teaching focus of the reform and innovation of the university curriculum system. As a public compulsory course for college students, college English course involves a large number of students and a long class hours. It is one of the main courses of development courses and ideological and political education. Ecological linguistics emphasizes the connection and connection between language and ecological environment, which has attracted the attention of the education industry in recent decades. As a language course, college English can be organically combined with ecological linguistics. Because language and its environment will interact, and language is the basis of social and cultural inheritance. Therefore, in order to improve the teaching level of college English, it is necessary to perfectly integrate ecological linguistics with ideological and politics of the course. However, in the current ideological and political teaching objectives of university courses, the integration of ecological linguistics has not been valued. According to the current background and the current classroom teaching mode of college English, this paper discusses the strategy of improving the ideological and political education level of college English courses under the guidance of ecological linguistics, in order to improve the current college English education system in China.
Field struggle and cultural construction in Talk Show Convention
Authors: Chai Yaxin
Published: April 2023

“Talk Show Conference” as a media platform, the content of the expression and China’s contemporary reality and young people’s life close. The program meets the cognitive logic and emotional needs of the young generation with a kind of emotional power full of intellectual style, builds a new feeling structure, and uses deconstructive expression to achieve positive energy empowerment. The program also forms a micro media field, and the maintenance of the “offensive” characteristics of talk shows the structural and combative qualities of the media field. However, the discourse expression of the program is difficult to break through the restriction of capital interests and has the free character of artistic creation. The arrival of satire is relaxation and reconciliation, and the final result of discourse resistance is partial sharing of the right of speech.
Environmental design strategies for integrating campus culture with students’ emotional needs
Authors: Cao Kai , Ye Qian , Qiu Siyue
Published: April 2023

In recent years, with the increasing attention and investment of Chinese governments at all levels to education, China’s campus culture construction is facing new development opportunities. Taking the indoor and outdoor environmental design of Wuhan Jingkai foreign language school as the main research object, this paper explores the theoretical basis, practical exploration and effectiveness of campus culture from the perspective of students’ emotional needs, and reflects on the construction of campus culture in environmental design. In view of the lack of comradeship and connotation in the environmental design of campus culture, this paper takes “based on students’ emotional needs” as the core, and tries to create a campus cultural environment in which students have a more sense of belonging and campus recognition.
Exploration of Space Art in Modern Landscape Architecture Design
Authors: Qiu Jie , Pan Lina
Published: April 2023

In modern landscape architecture design, various types of landscape space art constitute the overall effect of landscape architecture. Effective design and utilization of landscape space and reasonable organization of the relationship between plants, water bodies and activity places can greatly improve people’s aesthetic view of the environment. In modern landscape architecture design, the application of space art is a key content, and space exists objectively relative to time. In the actual process of urban construction, it is necessary to consider the basic character of landscape architecture and the hierarchy of mass demand development, add artistic content to modern landscape space, and give full play to the practical effect of landscape space. Space art is widely used in modern landscape architecture design, and more and more attention is paid to it with its own characteristics. Therefore, this paper will explore the space art in modern landscape architecture design, which is of great significance to improve the use and quality of space environment.
The Application of the Healing Value of Art in Modern Design
Authors: Zha Huimin , Ma Xinyue
Published: April 2023

This article conducts research on the application of the healing value of art in modern design through literature research and qualitative research methods, and concludes that the main methods of artistic healing include guiding understanding and exploring oneself, healing oneself through creation and appreciation, and unconscious spiritual healing. The purpose of this article is to find the embodiment of the healing value of art in modern design. By analyzing the embodiment of the healing value of art in children’s picture books and poster designs, we can find the important application principles of the healing value of art in modern design, and provide reference for other modern design categories to maximize the healing value of art. The significance of this study is different from artistic therapy, which focuses on the medical industry. Instead, it focuses on the prevention and control of psychological problems and social instability factors, reducing negative phenomena through psychological cues, and making people more aware of themselves through artistic therapy, curing themselves in a timely manner, and avoiding negative extreme behaviors.
Research on the strategy of promoting the revitalization of traditional crafts by personalized design in Intangible cultural Heritage exhibition
Authors: Wang Shanshan , Zhang Lei , Zhao Jinlong
Published: April 2023

Intangible cultural heritage is a concept closely related to the nation and the country, protecting the intangible cultural heritage has an important strategic significance for the cultural development of our country. The intangible cultural heritage is the essence of national culture, the symbol of national wisdom and the crystallization of the national spirit. Starting from case analysis, this paper summarizes the “experience” of personalized design of intangible cultural heritage exhibition and promotes it, avoids the formalization, formalization and fragmentation of intangible cultural heritage display means, and provides a new research idea for the revitalization and innovation transformation of traditional technology. Breaking through the previous theoretical research, this paper carries out a detailed study on the evolution and spatio-temporal design of the case information of intangible cultural heritage exhibition at home and abroad, and provides reference for the “strategy” of the personalized design of intangible cultural heritage exhibition to promote the revitalization of traditional crafts. Therefore, the research in this paper is realistic and practical. Therefore, the research methods pay attention to the combination of theoretical research and empirical research, the combination of comprehensive research and case study, and pay more attention to empirical research and comprehensive research.