bluuebunny/crossref_metadata_2025 huggingface dataset:
THE STUDENTS’ PERCEPTION OF BRITISH AND AMERICAN CULTURES IN SENIOR HIGH SCHOOL INTERLANGUAGE ENGLISH TEXTBOOK (This Case Study at One of Senior High School in Garut)
Authors: Patimah Euis
Published: April 2023

Awareness of the existence of foreign cultures in Indonesia in various fields, especially in the field of education, that the influence of foreign cultures can have positive and negative effects on school students. What is meant by cultural awareness is Cultural Awareness: An introduction to the nuances of one's own culture and that of other cultures. Cultural Competence: The ability of individuals to use academic, experiential, and interpersonal skills to enhance their understanding and appreciation of cultural differences and similarities within, between, and between groups. This study aims to understand cultural awareness and the impact of foreign culture on students in schools. Qualitative methods used through observation and interviews and semi-structured observation. The participants in this study were six twelfth grade students consisting of three girls and three boys at a high school in Garut. Findings found in this study are the perceptions of students who study English Interlanguage books, namely that there are many learning cultures that can be imitated because they bring positive things and improve student learning values and can also motivate students to be more critical of cultural awareness.
AN ANALYSIS OF SOCIAL CONFLICT IN TOER’S “MIDAH, SIMANIS BERGIGI EMAS”
Authors: Rezkiany Miftha Aulia , Rusmana Erik , Thamrin Husni , Harnady Kunkun K.
Published: April 2023

The title of this research is An Analysis of Social Conflict in Toer’s “Midah, Simanis Bergigi Emas”. This research attempts to analyze the social conflict in the novel and how the author conveyed the social conflict. This research used a descriptive qualitative method in order to answer the research question and used A. J. Greimas theory namely “Actant Scheme and Functional Structure” to process the data. Greimas’s theory used in this research is aim to know the structure of the story and how the conflict happen, because this theory shows the character and the story have a function that interplay with each other such as subject, object, sender, receiver, opponent, and helper. And the result from this research, the researcher found the conflict occurred in the story by the characters connected to the theory used. The researcher choose the book because the story contained in the work mostly talk about social life. Through this research, it can concluded that through literature, the author conveyed their opinion and message about social life and social conflict. In this research, the researcher found that the author conveyed the social conflict based on its acts of characters, sequences of events, and conversations between the characters.
STRATEGIES USED BY ENGLISH TEACHER FOR STUDENTS WITH SPECIAL NEEDS
Authors: Hapitri Resa
Published: April 2023

No one wants to be disabled or imperfect like other children. Being disabled doesn't mean they can't do anything. Thus, this research is focused on finding the strategies faced by English teachers in teaching students with special needs. The participant involved in this study is one of the English teachers in a special-needs school who has experience in teaching English. Data was collected using semi-structured interviews. The results show that the strategies used by teachers when teaching English are a student-centered approach and the use of repetition to help students remember lessons.
Publication trends and global productivity about the anterior cruciate ligament: a bibliometric analysis between 1980-2021
Authors: İPEK Deniz , DÜNDAR Abdulrahim
Published: April 2023

Aim: Due to anatomic, biomechanical, kinematic, biological and clinical data obtained as a result of many studies related to treatment and rehabilitation of injuries to the anterior cruciate ligament (ACL), among the most studied anatomic structures in the human body, the literature is continuously being updated and improved. In this study, the aim was to holistically analyze scientific articles about the ACL published between 1980 and 2021 using a variety of statistical methods.

Material and Method: Articles published from 1980 to 2021 about the ACL were obtained from the Web of Science (WoS) database and analyzed using statistical methods and bibliometric approaches. To identify trend topics and global cooperation, and to complete citation analysis, network visualization maps were used. The exponential smoothing predictor was used to predict the number of articles that will be published in the next 5 years. Spearman’s correlation coefficient was used for correlation research.

Results: A total of 11,077 publications were identified. Of these publications, 9101 (82.1%) were articles. The top 3 countries contributing most to the literature were the USA (3894, 42.7%), Japan (879, 9.6%) and Germany (616, 6.7%). The top 3 active organizations were Pennsylvania Commonwealth System of Higher Education (n=468), University of Pittsburgh (440), and University of California system (279). The top 3 journals publishing most articles were the American Journal of Sports Medicine (n=1614), Knee Surgery Sports Traumatology Arthroscopy (1418), and Arthroscopy: The Journal of Arthroscopic and Related Surgery (915). The most effective journal according to mean number of citations per article was the Journal of Bone and Joint Surgery (average citation per document: 80.7). The most active author was Freddie H. Fu (n=278, from University of Pittsburgh).

Conclusion: In this comprehensive bibliometric research about the topic of ACL, with a trend toward increasing publication numbers in recent years, the summary information for 9101 articles published between 1980 and 2021 was shared. According to analysis results to determine trend topics, the keywords studied in recent years include return to sport, ACL injury, anterolateral ligament, pivot shift, quadriceps strength, KOOS, ACL tear, ACL repair, meniscal repair, knee ligaments, tibial slope, posterior tibial slope, return to play, adolescent, graft failure and lateral meniscus.
Evaluation of pancreatic stent and/or suppository indomethacin efficacy in post ERCP pancreatitis prophylaxis: a single center experience
Authors: ERDOĞAN Çağdaş , GÜVEN İbrahim Ethem , BAŞPINAR Batuhan , KILIÇ Zeki Mesut Yalın
Published: April 2023

Aim: Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is a serious complication of ERCP. In this study, we aimed to compare the use of rectal indomethacin, pancreatic stenting or both techniques for prevention of PEP.

Material and Method: Patients who underwent ERCP for the first time due to choledocholithiasis between January 2022 and June 2022 were retrospectively reviewed. The clinical findings, demographics, laboratory records, endoscopic intervention characteristics, whether rectal indomethacin was applied before the procedure, whether pancreatic stent was placed or not were evaluated.

Results: A total of 367 patients who underwent ERCP for the first time were included in the study. The mean age was 61 (28-92) years and 53.4% were female. In 124 (33.8%) patients, involuntary guide-wire insertion into the pancreatic duct occurred during canulation. Pancreatic stent was placed in 82 (22.3%) of the patients. Rectal indomethacin was administered to 288 patients (78.5%), while indomethacin could not be administered in 79 patients (21.5%), because they did not give consent. When patients with involuntarily pancreatic canulation were evaluated, the rate of PEP was 3.6% in the stented group, while it was 15.3% in the stent-free group (p
The association between vitamin D level and ICU mortality in COVID-19 patients: a single center survey
Authors: ONUK Sevda , EREN Esma
Published: April 2023

Aim: Vitamin D, an immune modulator, may contribute COVID-19 infection. This study aims to assess the relationship between vitamin D value and clinical outcomes (need for mechanical ventilation (MV) support and intensive care unit (ICU) mortality) in critically ill patients diagnosed with COVID-19.

Material and Method: This study included critically ill adult patients diagnosed with COVID-19 infection. Serum vitamin D level was analyzed using liquid chromatography mass spectrometry. Vitamin D concentration was classified as normal (≥20 ng/mL) and deficiency (0.05).

Conclusion: Approximately 70% of our study sample has below the normal range of serum vitamin D value. Low serum vitamin D concentrations were associated with increased SOFA, creatinine, and troponin concentrations in patients with COVID-19 infection. Vitamin D deficiency was not a predictor of need for MV support and ICU mortality in COVID-19 patients.
Comparison of diagnostic methods in onychomycosis
Authors: ALTUN Ece , KUZUCULAR Elif , TOSUN Ayşe İstanbullu
Published: April 2023

Aim: Onychomycosis is a chronic fungal infection of the nail bed, plate, or matrix. This study aimed to compare the sensitivity of three diagnostic methods in the diagnosis of onychomycosis. Material and Method: This study included 39 patients with a clinical diagnosis of onychomycosis of the toenails, who presented to Medipol Mega University Hospital between May 2019 and August 2022. Using the nail samples taken from the patients, the results of the direct microscopic examination with standard potassium hydroxide (KOH), histopathological examination performed with periodic acid-Schiff (PAS) staining, and fungal agents that grew in fungal culture were noted. Results: Eleven (28.2%) patients were female, and 28 (71.8%) were male, with the mean age being 43.1±13.9 years. Of the patients, 53.8% had distal subungual onychomycosis and 46.2% had total subungual onychomycosis. The mean disease duration was 38.8±24.5 (12-120) months. Fungal infection was detected on direct microscopic examination with standard KOH in 66.7% of the patients, culture growth in 38.5%, and PAS staining on histopathological examination in 71.8%, and the sensitivities of these methods were determined as 74.3%, 49.2%, and 80%, respectively, with the negative predictive values being 30.8%, 16.7%, and 36.4%, respectively. Conclusion: Among the investigated methods, histopathological examination with PAS staining was found to have the highest sensitivity and negative predictive value in the diagnosis of onychomycosis.
R-Spondin1 and tumor necrosis factor-alpha in infertile women with polycystic ovary syndrome: relationships with insulin resistance and other parameters
Authors: GÜRBÜZ Tuğba , GÖKMEN Oya , AYAR MADENLİ Asena , DİLBAZ Berna
Published: April 2023

Aim: To evaluate the relationship between R-spondin1 (RSPO1) and Tumor Necrosis Factor-Alpha (TNF-α) levels with insulin resistance (IR) and other parameters in infertile women with polycystic ovary syndrome (PCOS).

Material and Method: This case-control prospective observational study was carried out on 84 patients admitted to the University of Health Sciences Etlik Zübeyde Hanım Training and Research Hospital Gynecology and IVF Clinic and Medistate Hospital Gynecology and IVF Clinic between September 2020 and June 2021. Women aged 18-36 years diagnosed with infertility and PCOS constituted the PCOS group. Women who were diagnosed with infertility but not PCOS formed the control group. Cases were divided according to their body mass index (BMI) values into obese (BMI≥25) and non-obese (BMI
Comparison of anterior midline incision and double incision in the surgical treatment of tibial plateau fractures
Authors: BOZDUMAN Ömer
Published: April 2023

Aim: Tibial plateau fractures are complex fractures that often develop after high-energy trauma, often involving intra-articular fractures. They are rarely treated conservatively. Surgical planning and approach are very important in preventing possible complications. In this study, we compared two different incisions in the same fracture types.

Material and Method: A total of 26 patients (20 males-6 females) with tibial plateau fractures were included in the study. Twelve of the patients were selected from those using anterior midline incisions, and 14 from those using double incisions as anterolateral and posteromedial incisions. The mean age of the patients is 50.8 (24-76) years. The distribution of patients according to fracture classification was 9 Schatzker type-6, 17 Schatzker type-5. Average follow-up time is 34.1 months (24.5-42.2). Postoperative complications, union time, joint range of motion, radiological Rasmussen criteria, Medial Proximal Tibial Angle (MPTA) and Posterior Proximal Tibial Angle (PPTA) measurements, Lachman and valgus-varus stress tests for ligament stability evaluation, Hospital for Special Surgery (HSS) and visual analogue scale (VAS) assessments were performed to evaluate the clinical status of the patients. Results were compared between both incision groups.

Results: Union in the anterior midline was 11.07 (±1.68) weeks and bilateral union was 9.96 (±1.35) weeks (p :0.074). Rasmussen scoring was 14.83 (±2.16) in the anterior group and 14.57 (±2.13) in the bilateral group (p:0.760). The MPTA was 85.35 (±3.97) degrees in the anterior group, and the MPTA was 86.40 (±3.74) degrees in the bilateral group (p: 0.492). PPTA was 80.77 (±1.95) degree in the anterior group, and PPTA was 80.85 (±1.78) degree in the bilateral group. HSS score was 70 (±9.02) in the anterior group and HSS score was 71.71 (±1.15) in the bilateral group (p:0.681). Rom was measured as 101.67 (±12.67) degrees in the anterior group and 107.86 (±13.54) degrees in the bilateral group (p: 0.243). The VAS anterior group was 2.83 (±1.64) and the VAS bilateral group was 3.36 (±2.09) (p:0.491).Instability was seen in 1 patient in the anterior group and 1 patient in the bilateral group (p:1). Infection was observed in 1 patient in the anterior group and in 3 patients in the bilateral group (p:0.598).

Conclusion: The anterior incision is as effective a surgical approach as bilateral incision in correct patient preferences. Surgical site visibility in anterior incision is satisfactory. The principal aspect is to perform the correct surgical planning for the correct patient.
Investigation of the relationship between food consumption and emotions that show psychobiotic characteristics of healthcare professionals: Karabük province example
Authors: GOBEL Pınar , DOĞAN Hilal
Published: April 2023

Aim: The aim of this study was to examine the relationship between psychobiotic food consumption and moods in healthcare professionals.

Material and Method: The research was conducted on healthcare professionals in December 2022. The research sample consists of healthcare workers over the age of 18 and at least secondary school graduates (physician, nurses, midwives, laboratorians, anesthesia technicians, audiologists, radiology technicians, medical secretaries, nurses, civil servants, psychologists and physiotherapists). A questionnaire comprised three parts. In the first part, there are questions containing general information about the demographic characteristics of the participants (age, educational status, profession, etc.). In the second part, the nutritional habits of the participants and the food consumption frequency form including the foods showed psychobiotic properties were used. In the third part, Depression Anxiety Stress Scale (DASS-21) was used. Body Mass Indexes were calculated by measuring the body weight and height of the individuals. Statistical analyses were performed by using SPSS (IBM SPSS Statistics 24.0) package program.

Results: 88 (57.5%) of the participants were female and 65 (42.5%) of them were male. 57 participants (37.3%) were in the age range of 40-49. Negatively, weakly statistically significant relationship was found between the age and anxiety scale (rho=-0.208; p=0.010). A negatively significant relationship was found between the anxiety subscale and foods such as cauliflower, cabbage, broccoli and oats/oat bran consumption (rho=-0.231, p=0.004; rho=-0.387, p=0.000). Fish and fish oil consumption and depression and stress subscales have been positively statistically significant relationship (rho=0.166, p=0.040; rho=0.200, p=0.013).

Conclusion: The consumption of probiotics and psychobiotics is increasing day by day with the increase in the level of knowledge. Because psychobiotics have effects in alleviating anxiety, depression and psychological problems, it is thought that they may have positive effects, such as reducing the effects of factors that cause obesity, such as emotional eating. In this study, there are relationships between depression, anxiety and stress and consumption of psychobiotic foods, but there is a need for more detailed and large-scale studies as there are many factors that can affect the level of stress and anxiety.
The usefulness of arylesterase in predicting contrast-induced nephropathy in ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention
Authors: KALAYCI Süleyman , HAMAMCIOGLU Ayse Ceylan , KALAYCI Belma
Published: April 2023

Aim: Oxidative stress is one of the causes of contrast-induced nephropathy (CIN). Paraoxonase1 (PON1), is one of the oxidative stress markers. The most sensitive method that has been in use to measure PON1 enzyme activity is the measurement of arylesterase (AREase) activity. To explore relationship between AREase activity and CIN development.

Material and Method: A total of 58 STEMI patients were included in our study. The patients were divided into two groups as CIN (+) and CIN (-). The success of AREase activity level in predicting the development of CIN was also examined by using ROC analysis.

Results: Out of the study patients, 13 were CIN (+) and 45 were CIN (-). AREase activity was found to be statistically significantly lower in the CIN (+) group (875 U/L vs 819 U/L, p= 0.004). In the regression analysis, diabetes mellitus, contrast volume and AREase activity were determined as independent risk factors in the development of CIN. As a result of the ROC analysis, we concluded that the AREase activity level
Immature granulocyte and other markers in prediction of mortality in spontaneous intracerebral hemorrhage
Authors: KOCATÜRK İdris , GÜLTEN Sedat
Published: April 2023

Aim: This study aims to evaluate immature granulocyte count (IG#) and percentage (IG%) in the prediction of mortality in spontaneous intracerebral hemorrhage (SICH).

Material and Method: Demographic characteristics and laboratory test results of patients diagnosed with SICH and admitted to the neurology clinic in a tertiary hospital between January 1, 2020, and January 1, 2022, were recorded. One hundred ten patients were included in the study. While 80 of these patients constituted the group that recovered after treatment, 30 of them formed the group that died despite treatment. IG and other laboratory and clinic parameters were statistically compared in both groups.

Results: Of 110 patients, 45 (42.7%) were female, and 65 (57.3%) were male. IG counts were higher in the non-survival group than in the survival group (p=0.001). When the patients were divided according to low IG% (=0.6), 30 patients were in the high IG# group, and 80 patients were in the low IG% group. White blood cell (WBC), neutrophil count (NEUT#), monocyte count (MONO#), IG#, neutrophil-lymphocyte ratio (NLR), and hemorrhage volume (HV) values were statistically significantly higher in the high IG% group than in the low IG% group; Glasgow coma score (GCS) and percentage of lymphocytes (LYMPH%) values were significantly lower too. In addition, the mortality rate in the high IG# group was significantly higher than the mortality rate in the low IG% group (53.23% vs. 17.5%).

Conclusion: IG is a new, easily accessible, inexpensive, and promising marker for predicting in-hospital mortality in patients with SICH.
Evaluation of osteoporosis knowledge level of women who applied to the family medicine outpatient clinics of a university hospital
Authors: BİRİNCİ OCAK Bahar , CEYHUN PEKER Ayşe Gülsen , DAĞDEVİREN Murat
Published: April 2023

Aim: This study aimed to assess the knowledge, attitude, and behavior of women aged 18–45 years toward osteoporosis.

Material and Method: A total of 368 females (average age:32.59±7.58) who applied to the family medicine outpatient clinics between 15 May 2016 and 15 August 2016 participated in this study. Participants completed the revised osteoporosis knowledge test, which contained 12 socio-demographic questions.

Results: The average score for participants in the exercise subgroup was found to be 9.56±3.62 out of 20; the average score for the nutrition subgroup was 12.86±4.17 out of 26, and the average total score was 15.08 ± 4.82 out of 32. In general, the average score of participants was found to be 50% percent or less of the maximum scores of each subgroup of the questionnaire. This result suggests that women have inadequate knowledge about osteoporosis. Participants’ level of knowledge of osteoporosis was related to their education levels, occupational groups, and smoking status. High educational levels of participants correlated with high average scores (p
A comparative study of the effects of chronic kidney disease on sonographic arterial stiffness parameters in geriatric and normal population
Authors: DOĞAN Kamil , BAYKARA Murat , ÖZTÜRK Cansu
Published: April 2023

Aim: Due to its growing incidence rate worldwide, chronic kidney disease is a crucial public health problem which is strongly associated with cardiovascular disease. Cardiovascular disease in chronic kidney disease patients is characterized by arteriosclerosis and increased arterial stiffness, and is the leading cause of morbidity and mortality. A correlation was reported between an increased arterial stiffness and cardiovascular disease in high risk groups such as chronic kidney disease or hypertension as well as general undiagnosed population. Our aim was to show the changes in arterial stiffness parameters in patients with chronic kidney disease in the geriatric population.

Material and Method: 44 chronic kidney disease patients and 44 control group cases of the same age were included in the study. There were 20 female and 24 male cases in each group. Systolic and diastolic diameter were measured for all cases. Intima-media thickness was measured in carotid and femoral arteries. Arterial stiffness parameters were calculated using formulas. Systolic and diastolic arterial blood pressure and body mass index were measured. Their urea and creatinine values were recorded.

Results: There were no differences between two groups in terms of age and sex (p=0.069). Body mass index in the patient group was significantly lower compared to the control group (p=0.025). Systolic arterial blood pressure was higher in the patient group (p
Correlations of renal parenchymal attenuations and CT severity scores on three consecutive CTs in COVID-19 patients
Authors: KAYA Ahmet Turan , AKMAN Burcu
Published: April 2023

Aim: We aimed to investigate the correlation between the temporal changes of computed tomography severity score (CT-SS) ​​and mean renal parenchymal attenuation (MRPA) values in consecutive chest computed topographies (CT).

Material and Method: This retrospective, single-center study included 65 (≥18 years) COVID-19 patients with positive RT-PCR tests. A radiologist calculated three consecutive chest CT-SSs and measured the MPRAs on CTs from the upper half of each kidney included in the cross-section. Paired samples test and Wilcoxon signed-rank test were used to evaluate the temporal changes of mean renal parenchymal attenuation (RPA) and median CT-SS values, in three consecutive CTs. Spearman's test was used to evaluate the correlation of each RPA and CT-SS value on three consecutive CTs.

Results: The study population included 65 patients with a mean age of 61.49±13.91 years. A total of 36/65 (55.4%) were male. We found a significant increase between the first and second CT-SS (p
Role of systemic immune-inflammation index in predicting mortality in cancer patients in palliative care units
Authors: TUTAN Duygu , ESKİN Fatih
Published: April 2023

Aim: In our study, we aimed to investigate whether the systemic immune-inflammation index (SII) can evaluate mortality in cancer patients treated in the palliative care unit (PCU).

Material and Method: Cancer patients who received palliative care treatments in the PCU were screened retrospectively, and 309 patients were included in the study. The patients were divided into two groups; hospitalizations ending with discharge as Group 1 (n=154) and hospitalizations ending with exitus as Group 2 (n=155). SII values of the two groups were compared. SII was calculated with the formula of neutrophil count x platelet count / lymphocyte count. To determine the best cut-off value for the mortality distinction ability of the SII, a Receiver Operating Curve (ROC) analysis was used.

Results: The mean age and distribution of genders of the two groups were similar (p=0.706, p=0.964). There was a statistically significant difference between the SII values of the two groups (p
Current treatment approaches of newly graduated, intern dentists and dentists in doctoral and specialty training to teeth with excessive substance loss (cross-sectional study)
Authors: ALTAN Bike , FİLDİŞİ Mehmet Ali , ÇINAR Şevki , AYDEMİR Elifnur , ÖZKAN Davut
Published: April 2023

Aim: New treatment options have been developed as alternative post-retaining restorations and crowns that preserve remaining tooth tissue in endodontically treated teeth with excessive substance loss. This study, current treatment approaches newly graduated, intern and doctoral or specialist dentists in teeth excessive coronal destruction were evaluated.

Material and Method: This cross-sectional study, online questionnaire consisting of 22 questions, 3 parts was applied. First part consists of demographic information participants, second part consists of questions measuring awareness about preferred indirect restorations, last part consists of current treatment approaches newly graduated, intern and doctoral or specialist dentists. Total 234 voluntary participants questionnaires were evaluated. Obtained data were analyzed with IBM SPSS V23.

Results: In restoration of endodontically treated buccal mesial walls (least 2 mm thick) molars, participants all 3 groups preferred posterior adhesive indirect restorations according to their titles. Considering level of awareness, participants high group preferred posterior adhesive indirect restorations more in restorations endodontically treated buccal lingual walled molar teeth. Participants all 3 groups preferred use fiber under composite strengthen teeth in the restoration of teeth with excessive substance loss.

Conclusion: According to the results, it was determined that awareness and knowledge level of dentists who received specialty or doctoral training about new current treatments was higher than other newly graduated and intern dentists. It was observed that participants group with high level awareness mostly preferred posterior region indirect adhesive restorations such as endocrown and onlay.
Does YouTube™ give us accurate information about bruxism?
Authors: BİLİR Halenur , YILANCI Hilal
Published: April 2023

Aim: The aim of this study is to evaluate the quality of the information provided by the most watched videos about bruxism on YouTube™.

Material and Method: The results of YouTube™search were examined using the keyword “bruxism”. The searching limited to the first 130 videos. DISCERN and the video information and quality index (VIQI) and the criteria were used for evaluating the videos. Also, the interaction index and the viewing rate of the videos were calculated. The Kruskal-Wallis H Test, Pearson's Chi-Square Test, Spearman's rho correlation were used for statistical analyses. Significance level was taken as p
Predictive value of inflammatory markers in gastric cancer
Authors: BAŞÇEKEN Salim İlksen , TİKİCİ Deniz
Published: April 2023

Aim: Many recent studies are increasingly shedding light on the nature of the relationship between cancer and inflammation. Neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR) platelet/neutrophil ratio (PNR), and Mean Platelet Volume (MPV) are proinflammatory markers, and their prognostic importance has been investigated in many solid cancers. In this study, we discussed the association of these derivative inflammatory markers, obtained from a cheap and simple peripheral blood test, with clinicopathologic variables in patients undergoing gastrectomy for gastric cancer.

Material and Method: The retrospective database of a total of 148 patients who were operated for gastric cancer in the Diyarbakır Gazi Yaşargil Training and Research Hospital Department of Surgery was analyzed. All blood results and pathology reports of the patients were reviewed retrospectively. Demographic characteristics of the patients and pathological features of the tumor were extracted from the database. NLR, PLR, PNR and MPV values were calculated from peripheral blood cell counts. Data were analyzed using SPSS version 24.0.

Results: PNR and MPV values were statistically significant according to N and T stage of the tumor, respectively (p=0.035, p=0.011). In MPV, this difference was statistically observed between T1 and T2 tumors (p=0.029). PLR and NLR values did not show a significant difference according to the size of the tumor (p>.05).

Conclusion: MPV values are significantly associated with tumor T stage. PNR values are significantly associated with tumor N stage. However, the clinical implications and the added value to clinical practice require further research.
Analysis of perinatal outcomes of pregnancies from consanguineous marriages in a tertiary hospital in Bursa, Turkey
Authors: KARAŞİN Süleyman Serkan , KAZANCI Elif Güler , PAKAY Kaan , ÖZYAMACI Berin , TÜYSÜZ Tuba Nur , ESEN Şeniz Kurtoğlu , TURANLI Cansel Ezgi
Published: April 2023

Aim: In this article, we aimed to contribute to the outcomes of the consanguineous marriage literature by analyzing fetal results in this population.

Material and Method: We included 185 patients in this retrospective research. Demographic, clinical, ultrasonographic and delivery data were received from electronic patient records. Also, we recorded the postnatal results, and findings of the infants. By combining all the data, we reported a descriptive analysis of the results of our consanguineous marriage cases with perinatology follow-up.

Results: We had 231 pregnant women in the study, and their mean age was 28.9 years. 117 (50.6%) of the pregnant women had first-degree, and 114 (50.4%) had second-degree consanguineous marriages. Fetal findings were evaluated as usual in 157 (68%) of the pregnant in the ultrasonographic scans performed between prenatal 20-24 weeks of gestation. When we look at the first postnatal examinations of the babies, no abnormal findings were in 134 babies (58.8%). Twenty-two infants (9.6%) were followed up in the neonatal intensive care unit with the diagnosis of transient tachypnea of the newborn, and phototherapy was required in 14 infants (6.1%) due to hyperbilirubinemia. The number of cases requiring surgical intervention after delivery or with significant life-threatening anomalies included 56 findings in 32 infants. There were spina bifida cases in 8 infants and hydrocephalus in 9 infants.

Conclusion: There was an increased level of congenital anomalies associated with consanguineous marriages. Health care centers should educate individuals regarding the negative role of cousin marriages leading to abnormalities in children.
Risk factors for hypocalcemia and correlation between thyroid volume and incidental parathyroidectomy after total thyroidectomy: single center experience
Authors: ŞIVGIN Hakan , BOSTAN Mustafa Sami
Published: April 2023

Aim: We aimed to investigate correlation between the effects of age, sex, disease, pathologic diagnosis, parathyroid autotransplantation, presence of parathyroid in the pathology specimen and clinicopathological variables and thyroid volume, postoperative hypocalcemia after bilateral total thyroidectomy.

Material and Method: A retrospective study planned in tertiary university hospital on patients undergone bilateral total thyroidectomy and neck dissection when necessary surgery for thyroid pathologies. Minimum calcium values in the postoperative period were recorded as transient or permanent hypocalcemia. The cases were statistically analyzed for the relationship between the volume of the thyroid gland removed and hypocalcemia. The effects of sex, pathological diagnosis, preoperative hyperthyroidism, anatomical retrosternal extension, number of parathyroid glands seen and preserved intraoperatively, parathyroid gland autoimplantation, parathyroid gland removal in the pathological specimen, nerve monitoring, bilateral total thyroidectomy and central and lateral neck dissection were analyzed for postoperative hypocalcemia.

Results: Totally 763 patients were included in the study. The mean age of the patients was 50.6 years (SD:12.8) and the sex of 575 (75.4%) patients was female. Hypocalcemia was more common in women than in men (31% vs 17%; p
Sloped marginal configuration design of implants as an alternative innovation to the grafting operations: a three-dimensional finite element analysis
Authors: TOPRAK Mehmet Emin
Published: April 2023

Aim: Dental implant operations often require bone grafting due to bone resorption in the buccal area, which make the treatment more complicated, increase the risk of complications, and results in extra costs and prolongation of treatment. This study aimed to evaluate the biomechanical behavior of the implants with a sloped marginal configuration design in the alveolar ridge with a level difference between the buccal and lingual bone levels using three-dimensional finite element analysis (FEA) method.

Material and Method: Two implant models with different marginal configuration designs were used in this study. Implants were placed in the posterior edentulous mandible models in which the buccal region had a 2 mm more resorption according to lingual region which were created by imitating natural bone resorption with FEA. Bone grafting was performed on the exposed buccal surface in the conventional flat marginal configuration implant model (Model 1). In contrast, the sloped marginal configuration implants were compatible with the difference in bone level and placed directly without any additional surgical procedures (Model 2). Than three unit fixed partial dentures were designed. The design of cortical and cancellous bones, prosthetic components, implants, abutment screws and abutments covering those in the edentulous mandible models were transferred to digital three-dimensional models that were created to mimicking the real structures. The models were fixed below and behind of the mandible with zero movement. Load transfer characteristics of both models under these essential limitations were evaluated under 200N foodstuff force.

Results: The highest von Mises stress value was observed as 69.300 MPa in Model 1 and 126.870 MPa in Model 2. The maximum principal stress values were 28.236 N/mm2 and 63.449 N/mm2; the minimum principal stress values were 38.346 N/mm2 and 43.643 N/mm2 in Model 1 and Model 2, respectively. The highest von Mises stress value, maximum principal stress and minimum principal stress values were found higher in Model 2 which was created with sloped marginal configuration design of implants but all values were observed within acceptable physiological limits.

Conclusion: The sloped marginal configuration design of implants can be a non-invasive and more economical treatment alternative modality compared to conventional flat marginal configuration implants with advanced surgeries during implant placement.
Evaluation of cases with early repolarization on electrocardiogram and normal population in terms of laboratory and clinical results
Authors: ÖZTÜRK Derya , ALTINBİLEK Ertuğrul , COŞKUN Abuzer
Published: April 2023

Aim: Early repolarization (ER) is a frequent indication, and it is important to correctly evaluate the effects of its benign and malignant forms in terms of prognosis. It was aimed to compare ER cases with the normal population in terms of multi-vessel disease, bypass and mortality.

Material and Method: This study comprised 776 patients aged 18 and older who admitted the emergency department between January 2015 and December 2020. 377 of these patients had ER in the electrocardiogram (ECG), 409 patients had normal ECGs and were added to the study as the control group. Age, gender, multi-vessel disease, by-pass and mortality relations of the patients were evaluated with angiographic findings.

Results: The mean age of 786 patients was 50.49±6.82 years, 372 (47.3%) were female, and the age range was 23-66 years (p
Carotid Doppler ultrasound measurements in allergic rhinitis patients
Authors: BEKİN SARIKAYA Pelin Zeynep , BAYAR MULUK Nuray , TAŞ Burak Mustafa , BASER Selcuk , ÇETİNKAYA Elif
Published: April 2023

Aim: We aimed to determine with carotid Doppler ultrasound (CDU) whether the increase in inflammatory cells and mediators plays a role in intima-media thickening in patients with allergic rhinitis (AR) and to correlate this with the severity of the disease.

Material and Method: In this retrospective study, CDU reports and images of allergic rhinitis patients were evaluated in Group 1 (n=16). Score for allergic rhinitis (SFAR) and blood parameters that Hemoglobin (Hb), White Blood Cells (WBC), C-Reactive Protein (CRP), sedimentation levels were noted. Control group without AR consisted of 17 patients. In both groups, the presence of plaque on common carotid artery (CCA), and internal carotid artery (ICA) and all intima-media thickness were noted by CDU.

Results: In our study, CCA intima-media thickness and ICA intima-media thickness values of the AR group were significantly higher than those in the control group bilaterally (p
Distribution of ABO blood groups and Rh factor in benign and malign thyroid nodules
Authors: DENİZ Muzaffer Serdar
Published: April 2023

Aim: Many factors affect the diagnostic value of the fine-needle aspiration biopsy applied for these thyroid nodules. I aimed to investigate whether one of these factors would be ABO blood groups and Rh factor and examine the relationship of these factors with the Bethesda categorization. Additionally, I aimed to evaluate ABO blood groups and Rh factors in patients with thyroid cancer.

Material and Method: This study was planned in a cross-sectional retrospective design. The data of the patients were obtained from the hospital data bank. In the analysis of 801 patients following the acceptance criteria, 412 patient data were obtained. Patients were divided into 4 (O, A, B, and AB groups) according to their blood groups and analyzed for nodules (solitary/ multinodular). Nodules were divided into malignant and benign, according to histopathological diagnosis, and all were analyzed.

Results: There was no difference in analyzing the demographic data according to the blood groups. The rates of the FNAB history were 51 (32.3%), 39 (24.2%), 14 (26.4%), and 13 (32.5%) in the same order of blood groups (p=0.393). In the analysis of the nodule type, multinodular did not differ from solitary nodules among the blood groups [O: 141 (89.2%); A:140(87%), B: 46(86.8%), and AB: 35(87.5%)]. Thyroid function status (euthyroid, hypothyroid, or hyperthyroid) was similar for all the blood groups (p=0.815). The O-group had 1 (0.6%) patient with Bethesda score-6, and the A-group had 2 (1.2%) patients with Bethesda score-6. For Bethesda score-5, per blood group had 2 patients. The histopathological distribution of malign nodules (p=0.782) is as follows: O-groups: 6 (33.3%) (Rh+:27%; Rh-:5,5%), A groups: 7(63,6%) (Rh+:54,5%; Rh-:0,9%), B groups: 2(20%)(Rh+:20%; Rh-:0%) and AB groups: 1(33%) (Rh+:33%) Rh-:0%).

Conclusion: Malign nodule rate was highest in the A-group and lowest in the B groups, although it did not differ in the overall analysis. No relationship was found between the Bethesda categorization of nodules, their sizes, type of nodules, type of thyroid cancer, and ABO blood groups.
Complications of total knee arthroplasty and the development of late deep infection in patients with rheumatoid arthritis
Authors: YAZICI Alikemal
Published: April 2023

Aim: This study aimed to assess complications and the presence of late deep infection in patients with rheumatoid arthritis (RA) who underwent primary and revision total knee arthroplasty (TKA).

Materıial and Method: Between June 1997 and October 2022, cemented TKA that cut the posterior cruciate ligament (PCL) was applied to 50 knees of 34 patients with RA, and posterior-stabilized (PS) revision TKA was applied to 7 knees of 5 patients. All the patients enclosed in this study were adults diagnosed with RA by a rheumatology or physical therapy physician according to the RA diagnostic criteria recommended by the American College of Rheumatology in 1987. The diagnosis of infection was based on the Periprosthetic Infection Diagnostic Criteria of the 2018 International Periprosthetic Joint Infections Consensus Meeting.

Results: Complications were found in 9 (18%) of the 50 knees who underwent primary TKA. Postoperative serous discharge was observed in 3 (6%) knees, serous discharge and late partial rupture of the quadriceps tendon in 1 (2%), early deep infection in 1 (2%), late deep infection in 3 (6%), and hematoma in 1 (2%). Revision surgery was performed on 3 (6%) knees due to infection and on 4 (8%) knees due to aseptic loosening. Complications developed in 2 of these knees who underwent revision TKA, 1 (14.3%) knee with periprosthetic fracture in the femur in the first postoperative year, and 1 (14.3%) knee with early deep infection. Deep vein thrombosis (DVT), pulmonary emboli (PE) and heterotopic ossification (HO) were not observed in any patient.

Conclusion: In patients with rheumatoid arthritis, total knee arthroplasty increased chronic late deep infection and the associated need for revision surgery, and decreased the rates of DVT, PE, HO.
Does recipient weight and surgical approach really matter in pediatric renal transplantation?
Authors: EREN Eryigit , DİNÇKAN Ayhan
Published: April 2023

Aim: To compare the outcomes between low-weight (15 kg) children who underwent renal transplantation (RT) and investigate the impact of the surgical approach (intraperitoneal or extraperitoneal RT).

Material and Method: This study was designed as an observational single-centre study and was conducted in Istinye University Hospital, Istanbul, Turkey, between January 2018 and June 2021. Data including age, gender, weight, surgical approach (intraperitoneal/extraperitoneal), complications, length of hospital stay, graft and patient survival were collected. Low-weight (LW) and normal-weight (NW) patients were compared. A p value less than 0.05 was considered statistically significant.

Results: Overall, 107 (33 LW and 74 NW) patients aged between 1 and 17 were included. The LW group had a significantly lower age and a significantly longer duration of intensive care unit (ICU), and inpatient floor stays than the NW group (p
The late-term results in our patients operated for lumbar spine fractures
Authors: İZCİ Emir , PEKİNCE Oguzhan , KESKİN Fatih
Published: April 2023

Aim: The current study aimed to evaluate the late-term results of patients operated for lumbar spine fractures in our clinic.

Material and Method: 134 patients from January 2012 to January 2020 were treated with “short-segment pedicle instrumentation” for lumbar fractures in our neurosurgery department. Patients with a burst fracture of a single lumbar vertebra were included. The final sample consisted of 67 patients who were followed up over the years with radiographs before and after surgery and CT scans at the final follow-up.

Results: The results showed that 60% of the patients were rated as Denis P1, 35% as P2, and 5% as P3. Screw breakage was observed in seven patients, and 67 patients underwent revision surgery. Furthermore, the fractured vertebral body’s height was improved at the final follow-up stage, and an increase was witnessed from the preoperative figure of 16.4 mm to 25.8 at the final follow-up. At the final follow-up, the average Cobb angle was -11.6° preoperatively, and 6.3° after the operation and the correction loss was 12.1° which was severe in the middle part of the vertebra. By the final follow-up, disc spaces were narrowed below and above the fractured vertebra, and no correlation was found between clinical outcomes and adjacent disc degeneration.

Conclusion: We concluded that short-segment pedicle instrumentation produced satisfactory long-term results for lumbar fractures. To achieve adequate outcomes, correct management of complications and evaluation of various factors must be focused on.
The relationship between levels of apolipoprotein A1 and B in aqueous and serum with stage of diabetic retinopathy
Authors: ERBAHÇECİ TİMUR İnci Elif , ÖRNEK Kemal , ÇAĞLAYAN Osman
Published: April 2023

Aim: To determine the association between serum and aqueous apolipoprotein (Apo) A1 and Apo B levels and Apo B/A1 ratio in diabetic retinopathy.

Material and Method: This cross-sectional prospective study included 63 diabetic patients with or without retinopathy and 38 control subjects who underwent cataract surgery. The study groups were as follows; healthy subjects (Group 1), diabetic patients without retinopathy (Group 2), with non-proliferative diabetic retinopathy (Group 3), and with proliferative diabetic retinopathy (Group 4). Serum and aqueous Apo A1 and Apo B levels were determined by using an enzyme-linked immunosorbent assay.

Results: The amount of Apo B was determined in aqueous samples of all (100%) patients in Group 4 and 77.7% of patients in Group 3.The mean serum Apo B/A1 ratio was significantly higher in Group 2, Group 3 and Group 4 compared with Group 1 (p=0.002, p=0.037 and p
Accelerated Motion Towards Relativistic Velocities Described by Newtonian Mechanics
Authors: Haselhoff Eltjo
Published: April 2023

This paper presents a simple geometric derivation of the equations of motion for an object that accelerates towards a relativistic velocity. This is not done by using the Theory of Special Relativity, but with Newtonian Mechanics only. The results are identical to those derived by the Special Theory of Relativity, with the exception of the expression for time dilation. It is shown that this discrepancy is caused only in case the clock postulate is applied, which is used by Special Relativity, and which assumes that the time dilation of an accelerating object at any moment in time depends on its contemporary velocity only. It is shown that the clock postulate is violated in case of continuous acceleration, and an alternative expression for accelerated time dilation is presented without the need for the clock postulate.
A trial-dependent game with N-player
Authors: Hussain Abid
Published: April 2023

The trials in the classical N-player gamblers' problem are repeated independently until one or more players get bankrupt. In this research, we present a game that is stopped when the number of trials first reaches the minimum of the initial budget set by the players. We executed this game for N players and determined the probability distribution of the fortune for both symmetric and asymmetric games. The exact expressions for the expected fortune and variance of the distribution are derived.