bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of dithranol and butantrone in short contact therapy of psoriasis
Authors: Göransson A
Published: August 2023

Thirty psoriatic out-patients were treated as a right-left comparison with dithranol (0.1, 0.5, 1, 2%) and butantrone (0.66, 1.3, 2.7, 3.9%) short contact therapy, both in white petrolatum. Fifteen of the treated patients cleared well and no obvious differences between the treated sides were clinically observed. Six patients showed some improvement, but in four of them the dithranol treated side cleared sooner and the therapy was continued with dithranol short contact therapy on both sides. In two patients the thick lesions cleared slowly and the therapy was continued with dithranol in Lassar´s paste. The treatment was discontinued in nine patients: in five patients because short contact therapy was ineffective and in one patient because of strong skin irritation on both treated sides. In three patients the treatment was discontinued for non-medical reasons. Butantrone has an antipsoriatic activity almost equal to that of dithranol. When short contact treatment is used, erythema and staining with butantrone are weaker than with dithranol. Because the short contact tolerability of butantrone was good, it might be possible to start with higher concentrations.
Can the clinical efficacy of different antibiotic dosage regimens in gonorrhoea be predicted from the gonocidal effect of the corresponding plasma level profiles simulated in vitro?
Authors: Korting HC , Ollert M  , Lukacs A , Schäfer-Korting M
Published: August 2023

Two different gonococcal strains with equal minimum inhibitory concentrations of ceftriaxone are exposed to continuously changing concentrations of this antibiotic simulating the ones found in man after the single intramuscular application of different doses (1,000, 250, 125, 50 and 25 mg). In general the bactericidal effect on both strains decreases more or less steadily with decreasing concentrations of ceftriaxone. One of the strains, however, shows a markedly dropped bactericidal effect as soon as the dosage is further reduced from 250 mg. These findings agree with previous experience from clinical dose-range finding studies. Thus the in vitro model presented here may be valuable for predicting both the optimum dosage and the clinical efficacy of new treatment protocols for gonorrhoea.
Seasonal variation in urinary excretion of 5-S-cysteinyldopa in healthy Japanese
Authors: Ito S , Kato T  , Fujita K
Published: August 2023

The urinary excretion of 5-S-cysteinyldopa was examined in 10 healthy Japanese subjects once a month during a period of one year. The mean values were highest in August (296 micrograms/day) and lowest in February (141 micrograms/day). Individual variations were so great that only a weak difference was observed (p less than 0.05).
Focal naevoid hypotrichosis
Authors: Barth JH , Dawber RP.
Published: August 2023

A case of naevoid hypotrichosis affecting two symmetrical areas in the parietal regions is described.
Reproducibility and variability of transepidermal water loss measurement. Studies on the Servo Med Evaporimeter
Authors: Blichmann CW , Serup J.
Published: August 2023

Recording technique and accuracy of the Servo Med EP1 evaporimeter were studied. The technical accuracy of this equipment was found high with a coefficient of variation of 3.3%. Measurements of transepidermal water loss (TEWL) were performed on the palm of the hand and on the flexor side of the forearm in 10 healthy volunteers. Continuous registrations were undertaken for a three-minute period and repeated immediately thereafter. Values reached a linear state 30 sec after application of the probe. The variation of TEWL in relation to time was determined in the same individuals. Measurements were repeated after 1 hour and 24 hours. In conclusion, though the TEWL as measured by the Servo Med evaporimeter shows a considerable interindividual variation, the intraindividual variation and the variation by time are relatively minor. We recommend that more detailed studies are based on paired observations, with recordings read 30 sec after application of the probe onto the skin.
HLA-B39 and the axial type of psoriatic arthritis
Authors: Crivellato E , Zacchi T.
Published: August 2023

The frequency distribution of HLA-B38 and HLA-B39 was studied in a group of 50 unrelated psoriatic arthritis patients. A high increase of HLA-B39 was noted in the subgroup with axial arthropathy. All B39 positive patients presented with spondylitis and/or sacroiliitis. The hypothesis is formulated that HLA-B39 may discriminate a genetic subset of psoriatic arthritis characterized by a particular susceptibility to develop axial involvement.
Vasculitis simulating eczematous dermatitis due to C2 deficiency
Authors: Irestedt M , Månsson T  , Svensson A
Published: August 2023

In a patient with total C2 deficiency and repeated respiratory infections a papulovesicular rash showed to be due to leukocytoclastic vasculitis. The patient´s brother also had a total deficiency of C2 but no clinical symptoms. HLA-investigation in both him and the proband showed the genotype commonly reported in cases with homozygous C2 deficiency. Their heterozygous mother and sister had slightly decreased C2 levels.
Melittin-induced alteration of epidermal adenylate cyclase responses
Authors: Kajita S , Iizuka H.
Published: August 2023

Using an in vitro pig skin-slice incubation system, we investigated the effect of melittin, a phospholipase A2 (PLA2) stimulator, on the adenylate cyclase-cyclic AMP (cAMP) system. Significant decreases of various epidermal (beta-adrenergic, adenosine, and histamine) adenylate cyclase responses were observed as early as 1 h following the melittin treatment (50 micrograms/ml). The effect of melittin was concentration-dependent and the minimal concentration of melittin was 10 micrograms/ml for the inhibition of the beta-adrenergic adenylate cyclase response, whereas more than 50 micrograms/ml concentration was required for the inhibition of the adenosine and histamine adenylate cyclase responses. There was no significant difference in either low or high Km cAMP phosphodiesterase activity between control and melittin-treated skin. The beta-adrenergic augmentation effect by various chemicals (colchicine and Ro10-1670, an active form of Ro10-9359) were suppressed by the simultaneous addition of melittin in the incubation medium. Our data indicate that melittin affects not only on the beta-adrenergic adenylate cyclase system but also on the adenosine and histamine adenylate cyclase systems. However, the beta-adrenergic system was shown to be more sensitive to melittin than the other receptor adenylate cyclase systems.
Acrosyringeal lichen planus
Authors: Enhamre A , Lagerholm B.
Published: August 2023

Six patients with lichen planus or lichenoid toxicodermia are described. A dermal lymphocytic infiltrate in juxtaposition to the acrosyringium and liquefaction degeneration of the acrosyringeal basal cell layer were prominent findings. Three patients had no medication. In two there was an association with beta-adrenoceptor blocking drugs. The term acrosyringeal lichen planus is proposed for this histological picture and some explanations for its pathogenesis are suggested.
Hemidesmosome deficiency of gastro-intestinal mucosa, demonstrated in a child with Herlitz syndrome and pyloric atresia
Authors: Weber M
Published: August 2023

In an 11-day-old premature girl with Epidermolysis bullosa atrophicans generalisata gravis Herlitz and pyloric atresia, hypoplasia of hemidesmosomes in the skin, the gastrointestinal mucosa and the atretic pyloric segment was found by electron microscopy. Pyloric atresia is explained by hemidesmosomal defects causing junctional blistering of the mucosa, subsequent peptic digestion and inflammatory scarring reaction.
Granulomatous vasculitis as a complication of potassium iodide treatment for Sweet´s syndrome
Authors: Eeckhout E , Willemsen M  , Deconinck A , Somers G
Published: August 2023

A case of Sweet´s syndrome treated with potassium iodide is hereby described. The patient responded well a few days after the initiation of therapy, but the evolution was complicated with a severe clinical deterioration two weeks later. Systemic vasculitis was diagnosed on the basis of significant impairment of renal function, involvement of the eyes (papillitis) and the skin biopsy which showed a leukocytoclastic vasculitis. This systemic vasculitis was attributed to the potassium iodide therapy.
Glucocorticoid receptors in cultured human skin fibroblasts: evidence for down-regulation of receptor by glucocorticoid hormone
Authors: Oikarinen A , Oikarinen H  , Meeker CA , Tan EM  , Uitto J
Published: August 2023

In the present study, we have determined the specific glucocorticoid receptors in cultured human skin fibroblasts with [3H]dexamethasone as the ligand. The whole-cell assay was employed for determination of glucocorticoid receptor densities and binding affinities in fibroblast cultures established either from 16 healthy control subjects, from 4 patients with active progressive systemic sclerosis (PSS), from 3 patients with keloids and 3 patients with diabetes mellitus. The receptor densities in PSS, keloid, diabetes and control fibroblasts were in the same range, the values being 6.3 +/- 4.9, 7.7 +/- 3.6, 5.3 +/- 1.3 and 7.9 +/- 6.2 fmol/micrograms DNA (mean +/- SD), respectively. In further studies, the cells were incubated with 10(-7) M dexamethasone for 4 or 9 days before the receptors were assayed. The specific binding of [3H]dexamethasone in steroid treated cultures was 62 and 13% of that observed in controls, suggesting down-regulation. In contrast, incubation of fibroblasts with 10(-5) M all-trans-retinoic acid did not alter the binding of [3H]dexamethasone, suggesting lack of pharmacologic interference at the receptor level.
Anatomical Variations in the Branches of External Carotid Artery in Cadavers of Nepalese Origin
Authors: Mukhia Rajeev
Published: August 2023

Introduction: Knowledge of the position and the variations of the external carotid artery and its branches are essential for faciomaxillary surgery and surgeries of the neck. The variations in the branching pattern are also essential to avoid complications with catheter insertion of carotid arteries in various procedures and pre-operative angiography. The external carotid artery is an important route for administration of anticancer drugs for head and neck cancer, so the knowledge of anatomy of branching pattern of external carotid artery is clinically important. Materials and Methods: Total 30 external carotid arteries were included in the present study. The dissection of the external carotid artery was carried in the dissection hall of the Anatomy Department, Manipal College of Medical Sciences. When all the branches and course of the external carotid artery was visible, variations was noted. The length of artery was measured with the help of thread, scale and vernier calliper. All the data were analyzed with Microsoft Excel 2007 software and represented as mean and standard deviation. Results: Average length of the external carotid artery from its origin by bifurcation of the common carotid artery to its termination is 8.1 cm on the right side and 8.0 cm on the left side. 40 % of the external carotid artery shows variations in the branching pattern on right side where as 53.4 % of external carotid artery shows variations on left side. Conclusion: The mean length of external carotid artery is more or less difference between right and left side. The prevalence of variations of external carotid artery was seen more on the left side as compared to the right side. The variations in the branching pattern of external carotid artery are important to the vascular surgeons as well as radiologists to prevent diagnostic errors and also to avoid complications while performing surgery in the head and neck region.
Study of Variations in the Morphology of Liver in the Nepalese Cadavers
Authors: SK Sah
Published: August 2023

Backgrounds: Liver is the largest viscera, located in the right hypochondrium, epigastrium and left hypochondrium of the abdominal cavity. It is a wedge-shaped organ with its narrow end pointed towards the left. It is convex in the front, to the right, above, and behind, and is somewhat concave inferiorly, where it is moulded to the shapes of the adjacent viscera. Even though the surface is smoothly continuous, liver is customarily apportioned by the anatomists into a larger right and a smaller left lobe by the line of attachment of the falciform ligament anteriorly and the fissure for ligamentum teres and ligamentum venosum on inferior surface. Materials and Methods: The present study was conducted on 50 formalin fixed livers and gall bladders during routine labex of undergraduate students in the dissection hall of Anatomy department of Nobel Medical College Teaching Hospitals, Biratnagar, Nepal in the period of 3 years starting from June 2016 to May 2019. Each of the specimens was studied for morphological variations. Results: In the present study the livers with normal architectures were considered normal. Out of 50 liver specimens, 21 were normal without any gross anomalies with normal architecture. The remaining 29 specimens showed some short of accessory fissures and lobes on the different lobes of the liver. Out of 29 specimens in 2 specimens lingular process was observed arising from the left lobe. Hypoplastic left lobes was also observed in 2 specimens. Conclusions: Knowledge of morphological variations like atrophy, agenesis, presence of accessory lobes and fissures, presence of intrahepatic gall bladder and absence of normal fissure and lobe can cause diagnostic error in interpretation for the anatomists, radiologists and surgeons.
Comparative Modeling and Molecular Interaction Study for the Management of AMD and CRVO Ocular Disorder
Authors: P Srivastava
Published: August 2023

Age Related Macular Degeneration (AMD) and Central Retinal Vein Occlusion (CRVO) are the rare and leading cause of blindness among patients with ocular problem. Many proteins are reported in the progression of these ocular disorders. Proteins which are directly involved in the development of this disorder reported in the literature, their sequence related information retrieved from biological databases. In silico technique was implemented in order to characterize the properties and structures of the proteins using ProtParam. For studying about the potential phosphorylation sites in protein generally NetPhos server was used whereas for denoting the location of signal peptide cleavage sites and their presence the server which is used is SingalP server. For prediction of secondary structure prediction of proteins is done by using SOPMA. The SOSUI server performs the identification of trans-membrane regions. The 3D dimensional structure was modeled using Swiss Model Workspace and Modeller. Ramachandran plot was used to validate the stereochemical properties of the predicted structures because it is a very important step after 3D structure prediction. Docking of screened phytochemicals with selected proteins was performed by AutoDock. Docking study revealed that Curcumin (binding energy: -8.35) and Berberine (binding energy: -7.14) can be used as better therapeutic lead molecule for the cure of CRVO and AMD respectively.
Recent Advances in Management of Amblyopia
Authors: SB Gupta
Published: August 2023

Amblyopia is the most common cause of monocular vision loss in children. Global incidence is 3.7%. It may be due to early deprivation of vision or defocus in one eye, reflects an imbalance of input from the eyes to visual cortex .Not only monocular vision is reduced but binocular vision is also affected. Fellow Human brain is designed to allow both eyes to work together. If signals from one eye are blurred, brain blocks the visual input from that eye. In the visual pathway, the synapses are broken due to disuse of amblyopic eye. Along with visual coordination deficit, eye to hand and reading can be affected and selfperception may be diminished. A variety of amblyopia therapy options have been developed to treat amblyopia in children and adults. Amblyopia therapy options have traditionally been limited to penalization of non-amblyopic eye with either patching or medicinal penalization. Traditional approaches to diagnose and treatment have limited effectiveness, are uncomfortable for the patients and their families. Recent evidences shows that amblyopes possess binocular cortical mechanisms for both threshold and supra-threshold stimuli. Hence strategy may be based on binocular stimulation methods, aims to stimulate either eye leading to a concomitant improvement in monocular vision with reduction in suppression and strengthening of binocular vision.
Knowledge about Cataract and Associated Factors among Adults
Authors: HW Alemu
Published: August 2023

Introduction: Cataract is the leading cause of blindness globally and accounts for half of the total blindness in Ethiopia. Despite being treatable, the need for knowledge about cataract and its treatment options is a barrier to timely service in developing countries. Improving community knowledge about cataracts can be vital in improving eye care-seeking behavior. Objective: To assess knowledge and associated factors about cataract among adults in Kombolcha, Northeast Ethiopia. Methods: Community-based cross-sectional study was implemented. A stratified multistage sampling technique was used to select 847 study participants aged 18 years or older. A face-to-face interview was applied using a pretested structured questionnaire in the Amharic language. The collected data was entered into Epidemiological Information version 7 and exported to the Statistical Package for Social Sciences version 20 for analysis. Descriptive statistics and binary logistic regression with odds ratio were used. Variables with a p-value of less than 0.05 in multivariable logistic regression were considered statistically significant predictors for knowledge about cataract. Results: A total of 771 participants completed the study with a response rate of 91%. Of the total, 86.0% were from urban kebeles, and 50.8% were female. The median age of the participants was 30 years. About 75.6% (583) of individuals were familiar with the word cataract. Overall 537 (69.6%, 95% CI: 66.3- 72.9) had good knowledge about cataract. Higher educational status (AOR: 6.041; 95% CI: 3.106-11.746), being married (AOR: 1.787; 95% CI: 1.174-2.721), history of a previous eye examination (AOR: 1.619; 95% CI: 1.053-2.488) and positive history of cataract (AOR: 10.443; 95% CI: 2.078-52.493) were factors significantly associated with good knowledge about cataract. Conclusion: Considerable proportion of study participants was knowledgeable about cataract. Higher educational status, being married, having a previous eye examination and having a positive history of cataract had a significantly positive association with good knowledge about cataract. Boosting knowledge about cataracts is required for the community segment without formal education.
Clinical Outcomes of Nd: YAG Laser Posterior Capsulotomy: Impact on Intraocular Pressure, Refraction, Anterior Chamber Depth, and Macular Thickness
Authors: V Shah
Published: August 2023

Background: Nd: YAG laser posterior capsulotomy is a commonly performed procedure to treat posterior capsular opacification following cataract surgery. While the procedure is known to effectively improve visual acuity, its potential impact on intraocular pressure (IOP), refraction, anterior chamber depth (ACD), and macular thickness remains a subject of debate. This study aims to investigate the effects of Nd: YAG laser posterior capsulotomy on these ocular parameters. Methods: This study was designed as a prospective analysis conducted at a tertiary eye care center on patients who underwent Nd: YAG laser posterior capsulotomy at a tertiary eye care center between January 2020 and December 2020. Preoperative and postoperative measurements of IOP, refraction, ACD, and macular thickness were collected and compared. Statistical analyses were performed using paired t-tests, and p-values <0.05 were considered statistically significant. Results: A total of 30 eyes from 25 patients (mean age, 65.4 ± 8.2 years) were included in the analysis. Following Nd: YAG laser posterior capsulotomy, the mean intraocular pressure (IOP) increased from 15.2 ± 2.3 mmHg to 17.0 ± 2.7 mmHg (p < 0.001). The refractive status showed a mean myopic shift of -0.35 ± 0.16 diopters (p < 0.001,). Additionally, there was a statistically significant reduction in anterior chamber depth (ACD) from 3.15 ± 0.42 mm to 2.90 ± 0.37 mm (p = 0.003,). However, there was no significant change in macular thickness after the procedure (p = 0.287). Conclusion: Nd: YAG laser posterior capsulotomy leads to a mild but statistically significant increase in IOP and a small myopic shift in refraction. Additionally, the procedure results in a decrease in ACD but does not significantly affect macular thickness. Ophthalmologists should consider these effects when performing Nd: YAG laser posterior capsulotomy and carefully monitor patients postoperatively.
Fatores mais valorizados pelos consumidores no momento de escolha de uma empresa prestadora de serviços funerários sob a ótica dos 7p’s do marketing
Authors: BRUN HANDERSON MOLIN , Spanhol Finocchio Caroline Pauletto , Arakaki Geovana Júlia Pecois , Araújo Alexandro Moura , Maschio Hélio Augusto
Published: August 2023

As empresas funerárias são responsáveis por todo o processo de despedida dos entes queridos, utilizando técnicas e conceitos para que a experiência do cliente possa ser menos dolorosa. Os empreendimentos desse segmento também oferecem planos de assistência em vida (descontos em consultas médicas, odontológicas, farmácias, etc), conhecida como Pax. O objetivo deste trabalho é identificar quais fatores são mais importantes, dentro da ótica dos 7ps de marketing de serviços, para os clientes, no momento da contratação dos serviços. A metodologia utilizada foi de caráter quantitativo, os dados foram coletados através de questionário estruturado. Os fatores mais valorizados são: evidência física, em destaques para limpeza do ambiente e um ambiente agradável; pessoas, no sentido da gentileza e educação dos colaboradores.
Consumo, descarte e redes de significações de vestuário de segunda mão para consumidores de baixa renda
Authors: Pinto Marcelo de Rezende , Luna Batinga Georgiana , Leandro Zampier Ronan , Daniela Souza dos Anjos Patrícia
Published: August 2023

Considerando que o descarte ainda é um tema pouco explorado na literatura de consumo, este artigo relata resultados de uma pesquisa cujo objetivo foi investigar como se articulam o consumo, o descarte e a construção de significados de roupas usadas no contexto de comunidades de baixa renda. Foram conduzidas 25 entrevistas em profundidade com consumidores de roupas usadas em regiões carentes da cidade de Belo Horizonte. A partir da análise de três categorias que emergiram do corpus, os resultados apontaram que esse mercado é permeado por questões simbólicas principalmente no que tange à relação das pessoas com as roupas. Verificou-se também que o descarte das roupas surgiu como um elemento central para a constituição desse mercado.
Intercultural Communication of "Tanduk Majang" Song for the Madurese People
Authors: Muqit Abdul , Sueb  , Polii Intama Jemy , Sutaji Ahmad Aris Mundir , Nurhayati  , Imron Aly
Published: August 2023

This study examines the intercultural communication of the Madurese people through the song "Tanduk Majang." The song reflects the characteristics of a popular tribe in Indonesia, the Madura tribe. The data were taken from the well-known folk song entitled "Tanduk Majang." The data are in the form of words, phrases, and sentences. This research employed a descriptive qualitative approach proposed by Hubberman, Mail, and Saldana. The results of this study show that the song communicates the characteristics of the Madurese people. They are represented as friendly people, resourceful, and able to overcome every challenge they face. They are also energetic, happy, incredibly resilient and optimistic. It is concluded that the song can become a medium of communication, representing certain identifications to be shared with others. This study implies that folk songs may function as a resourceful medium to maintain cohesive relations among tribes in a country like Indonesia.
Legacy Facility: Decision-making Analysis. Case Study of a Pharma Company in Indonesia
Authors: Hermawan Pri , Wicaksono Muhammad Satrio
Published: August 2023

PT. ABCD has faced the issue of legacy facilities that become findings in routine inspections of NRA. The issue can be escalated to shut down the production facility due to the legacy facility hardly complying with cGMP. The study aims to choose the best alternatives of building a new facility, renovating the current facility, and toll manufacturing with consideration of financial, regulation compliance, project completion speed, and strategy risk. The study is using Analytic Hierarchy Process (AHP) to get a decision from the experts in PT. ABCD. The respondents are seven experts in many fields, including finance, project management, GMP, operations, demand forecasting, technological transfer, business development, cGMP engineering, and the management representative. To analyze the group decision-making, the results of each respondent are aggregated with a geometric mean. Compliance with regulation (0.356) was found to be the top priority, followed by strategy risk (0.295), project completion speed (0.250), and financial aspect (0.098). Results show that (a) building a new facility (0.4563) is the best alternative among the other alternatives, followed by toll manufacturing (0.3251) and renovating the current facility (0.2186); and (b) building a new facility is the best alternative among the other alternatives (0.4563) followed by toll manufacturing (0.3251) and renovating current facility (0.2186) with consideration of criteria financial aspect, regulation aspect, project completion speed aspect, and strategy risk aspect. We recommend implementing the project plan to build a new facility.
Stereotype Gender Pada Mahasiswa Universitas Negeri Padang Tahun 2019-2021
Authors: Rahayu Tiara , Fatmariza Fatmariza , Rafni Al , Muchtar Henni
Published: August 2023

This study aims to reveal gender stereotypes among college students. The focus of this research is on the indicators of the form, causes, and impact of gender stereotypes. This study used a descriptive quantitative method, with a stratified random sampling technique. Respondents in this study were 75 respondents. The results of this study indicate that as many as 38.67% of students do not have gender stereotypes, even so there are still students who have gender stereotypes as much as 29.33%. Based on the results of the study, it can be concluded that the understanding of gender stereotypes among students needs to be further improved so that gender justice and equality can be realized.
Pengembangan E-learning berbasis Edmodo pada mata pelajaran Ilmu Pengetahuan Alam untuk siswa kelas VIII SMP
Authors: Rahmatika Hidayati
Published: August 2023

This study aims to develop edmodo-based e-learning learning as a support for natural science learning in SMP Negeri 16 Padang. This type of research is research and development (Research and Development / R & D). The product development model used in this study is the flow from Thiagarajan namely 4 - D (Four-D Models) .. The results of the validity of the aspects of the media and material shows that edmodo-based e-learning is valid with light revisions, and from the point of view of students The edmodo-based learning produced is very practical to use. The results of testing the effectiveness of the product, Edmodo has been effective for use in science learning for VIII SMP with an average posttest higher than pretest. Thus it can be concluded that edmodo-based e-learning products are suitable for use in the learning process.
A Comparison Study On Reading Comprehension Between Male And Female Students
Authors: Witri Hildayanti , Fauzan Ansyari M.
Published: August 2023

This study was aimed at finding out the difference on reading comprehension between male and female students at the eleventh grade of State Senior High School 1 Bangkinang Kota. The research design was proactive ex post facto research. The population and sample was the eleventh social science students. The number of sampling was selected by using stratified disproportional technique. Inferential analysis “Independent Sample T-Test” technique was used to measure the difference on reading comprehension between male and female students and descriptive analysis was used to know the dominant factors that influence reading comprehension for male and female students. Based on the research findings, it was found mean score of male students was 61.87 and were categorized into enough level, then female students was 70.13 and were categorized into good level. Moreover, the sig was 0.012 < a (0.05). Therefore, it could be concluded that Ho was rejected and Ha was accepted, it means there is a significant difference on reading comprehension between male and female students at the eleventh social science class of State Senior High School 1 Bangkinang Kota. Whereas, the factors for male students were social environment (22.8%), talent (21.2%), background knowledge (20.6%), vocabulary (19.6%), and motivation (15.8%). While the factors for female students were motivation (22.2%), social environment (20.9%), background knowledge (20.5%), talent (18.6%), and vocabulary (17.8%).
Penggunaan media video dalam meningkatkan kualitas mengajar guru di sekolah
Authors: Aisyah Deca , Febriyenti Frety
Published: August 2023

This article analyzes the needs of teachers in an effort to improve the quality of teacher teaching by using technology and information through video media. Learning video media is a form of technology that is indispensable for teachers to support the successful implementation of effective and efficient learning. This is because learning video media can increase students' attention and interest in learning. The purpose of this study is to increase the use of instructional video media in the teaching and learning process and to improve the teaching quality of teachers in schools. The method used is descriptive quantitative method using quantitative data analysis techniques. The data collection technique used is a survey. Based on the data obtained, the results of this study indicate that 90% of teachers have difficulty in making learning media. In addition, 75% of teachers have limitations in the use of IT.
Adaptasi Semangat Merdeka Belajar dengan Penerapan Model Pembelajaran Project Based Learning Sebagai Bentuk Inovasi dalam Pembelajaran
Authors: Fitra Fitra , Maifa Sonia
Published: August 2023

The spirit of independent learning is a learning process where teachers and students have the freedom to explore knowledge and skills associated with the environment in order to produce human resources that fit the profile of Pancasila students and can compete in the professional world. The purpose of this study is to convey that the spirit of independent learning can be adapted to the learning process using a project-based learning model. The method used is literatur review with a descriptive qualitative approach. The results of this study are (1) the concept of independent learning includes 4 outlines, namely Minimum Competency Assessment, Character Survey, Expansion of Learning Outcome Assessment, and Equalization of Education Quality. (2) Independent learning includes 4 policies, namely national standard school exams organized by schools, minimum proficiency assessment and character surveys, simplification of learning planning plans, and new student admission zoning system (3) project based learning is considered relevant to be adapted to the spirit of independent learning because it involves student activity and experience in the field. Based on this explanation, this study concluded that the adaptation of the spirit of independent learning with learning project-based learnig models has a positive impact in increasing the activeness, curiosity, and spirit of learning of students.
Game Lino dalam Pembelajaran Bahasa Inggris Materi Many Things Kelas VII Sekolah Menengah Pertama
Authors: Maita Sari Nora , Indah Putri Lidya
Published: August 2023

English is an international language where many countries use English in their daily life, such as in Malaysia. English with "Many Things" material, which is a material in English learning that teaches students to get to know the objects around them, not only knowing them but here students also learn how to write them. The problem in real life is that books do not play a role in children learning English because the books only display text and pictures so that many students do not know how to pronounce the English they are learning. With this Lino game, students can get to know the objects around them by writing the names of the objects displayed in the game and listening to how to kiss what they have written. This game serves to make it easier for children to learn English quickly, and not only that, with this game, students in learning also feel entertained by the attractive animation display.
Pengembangan Multimedia Interaktif Berbasis Adobe Flash Pada Mata Pelajaran Bimbingan TIK Kelas VIII SMP
Authors: Sesmiati  , Zuliarni
Published: August 2023

The development of interactive multimedia is carried out as an effort to solve student learning problems, where the limited number of hours of lessons at school, practical material, the risk of students being left behind is greater, causing disturbances in the classroom such as students often making noise and sometimes disturbing their friends. This is also caused by the limited existing learning media, the lack of teacher variation utilizing educational media, both conventional and technology-based media. This study uses the Research and Development (RnD) research method, using the Borg and Gall development model. The development procedure in this study is procedural and simplified according to the needs of the researcher, namely (1) data collection, (2) product design, (3) product development, (4) validation and revision, (5) product trial, (6) product end. Product validity was carried out by 3 people, namely 2 media validators and 1 material validator, while the number of research subjects was 24 students of SMP Negeri 1 Ampek Angkek. The data collection instrument is in the form of a questionnaire, assessment formats and test questions. Data were analyzed descriptively qualitatively and quantitatively. Based on the results of the feasibility assessment of the media validator and material validator, it can be concluded that the results of the assessment by two media experts are categorized as "Very Valid" for use with the number of assessments from validator I getting an average of 4.96 and validator II an average of 5.00. While the results of the material expert's assessment were categorized as "Very Valid" with an average of 4.44. The results of the interactive multimedia practicality test are in the "Practical" category with an average rating of 4.37. The results of the effectiveness test show that t_count > from t_table so that it shows a significantly higher difference between pretest and posttest. Based on the results of the validity test, practicality test and effectiveness test, it can be stated that this interactive multimedia based on Adobe Flash CS6 is suitable for use in learning.
Pengembangan Electronic Dictionary Card Berbasis Multimedia Interaktif Pada Mata Pelajaran Bahasa Inggris Kelas VII SMP
Authors: Fitra  , Rahmi Ulfia , Hendri Nofri , Eldarni
Published: August 2023

Penelitian ini bertujuan mengembangkan multimedia pembelajaran interaktif yaitu E-Dictionary Card yang valid, praktis, dan efektif pada pembelajaran Bahasa Inggris. Keterbatasan perbendaharaan kosakata dan penggunaan buku teks, LKS, dan powerpoint yang dianggap menjenuhkan oleh peserta didik melatarbelakangi proses pengembangan yang dilakukan. Penelitian ini merupakan penelitian Research & Development (R&D) menggunakan model pengembangan ADDIE. E-Dictionary Card yang dikembangkan dilakukan uji validitas kepada 3 orang expert, uji praktikalitas kepada 20 orang, dan uji efektivitas kepada 20 orang. Hasil penelitian pengembangan yang dilakukan memperoleh tingkat validitas 3,9 untuk validasi materi, 3,875 untuk validasi media, 3,56 untuk uji praktikalitas, dan signifikansi (p value) sebesar 0.00 untuk uji efektivitas. Sehingga, dapat disimpulkan bahwa multimedia yang dikembangkan dinyatakan valid, praktis, dan efektif untuk digunakan pada pembelajaran Bahasa Inggris kelas VII SMP.
A Study of The Phenomena of Visual Pollution in Halabja and its Effects on The Psychology of Citizens
Authors: Baram Hasim Othman , Mohammed Osama Ashraf , Salih Aram Omer , Omar Daban Kadhim , Mahmood Rawa Fayaq , Karim Talar Mohammed
Published: August 2023

Each year, new environmental threats develop. These threats can be either natural or man-made. Human-caused environmental effects are becoming more prominent and influential. Their activities and deeds endanger the ecosystem and future generations. Human, economic, and political actions are the fundamental causes of environmental pollution and damage. As a result, environmental changes have an impact on people's physical and emotional well-being. Nobody questions the fact that the environment is deteriorating. Numerous studies have demonstrated that this transition occurs and has an impact on our lives. One of the most serious concerns confronting the world today is environmental contamination. A polluted environment is one of the difficulties that everyone in society encounters. Visual pollution is a type of environmental contamination. Any human action that affects the environment is referred to as visual pollution. A lack of environmental knowledge and irresponsibility causes visual pollution. There is no doubt that pollution harms the environment's living and inanimate components because the environment is necessary for human life and other kinds of life. Any alteration in the environment will endanger the entire land ecosystem. There are various types of environmental pollution, with water, air, soil, sight, and sound pollution all the most serious..
BENARKAH LAGGING AUDIOVISUAL DAPAT MEMUNCULKAN EMOSI?: SEBUAH KAJIAN EMOTIONAL STIMULUS
Authors: Qinthara Muhammad Fadhlan , Anshari Nadhira Ivana , Bagaskara Bagus , Suryadimulya Raden Dan Yuki Adhitya Fitrayana Al Fajr , Fitriana Efi
Published: August 2023

Dalam kehidupan sehari-hari, kata lagging sering kali digunakan pada sebuah kondisi adanya ketidaksesuaian waktu antara eksekusi yang dilakukan dengan hasil atau outcome dari eksekusi tersebut. Lagging yang dialami oleh pelajar dapat berdampak negatif dalam kegiatan pembelajaran. Proses pembelajaran berfokus pada kognitif pelajar, namun tidak terlepas juga dari faktor emosi. Situasi pembelajaran dapat memunculkan pengalaman emosional pada suasana kelas. Penelitian ini bertujuan untuk mengetahui pengaruh lagging pada media pembelajaran audiovisual terhadap achievement emotion pada pelajar. Penelitian ini menggunakan pendekatan eksperimen. Alat ukur yang digunakan dalam penelitian ini adalah Achievement Emotions Questionnaire – Short Version (AEQ-S) yang mengukur emosi pada kondisi pembelajaran. Sampling kuota acak dilakukan terhadap 60 pelajar yang terbagi menjadi dua kelompok, yaitu kelompok kontrol dengan jumlah 30 partisipan dan kelompok eksperimen berjumlah 30 partisipan yang diberikan stimulus lagging. Hasil penelitian menunjukkan bahwa lagging media pembelajaran audiovisual sebagai emotional stimulus dapat memengaruhi achievement emotion pada pelajar, ditunjukkan dengan kelompok eksperimental yang mengalami peningkatan pada emosi marah (anger), pasrah (hopeless), bosan (boredom), dan rendahnya emosi harapan (hope).
GAMBARAN ACADEMIC HARDINESS PADA MAHASISWA PROGRAM STUDI PROFESI DOKTER UNIVERSITAS PADJADJARAN
Authors: Rifandi Raisya Indah Mewangi , Kustimah Kustimah
Published: August 2023

Mahasiswa program studi Profesi Dokter Universitas Padjadjaran mempunyai tuntutan akademik yang tinggi seperti jadwal yang padat, ekspektasi lingkungan sekitar, materi ajar yang banyak, pemberlakuan SOP, kerja tim, perbedaan karakteristik dokter supervisor, hingga lingkungan pertemanan yang dinamis. Hal-hal tersebut perlu dikelola agar mahasiswa dapat memberikan performa yang optimal. Penelitian ini bertujuan untuk melihat gambaran academic hardiness pada mahasiswa program studi Profesi Dokter Universitas Padjadjaran menggunakan Revised Academic Hardiness Scale (RAHS). Penelitian ini merupakan studi deskriptif dengan populasi penelitiannya adalah mahasiswa program studi Profesi Dokter Universitas Padjadjaran. Teknik random sampling digunakan untuk memilih partisipan yang sesuai dengan kriteria, dan didapatkan 86 mahasiswa program studi Profesi Dokter yang menjalani masa klinik di rumah sakit. Pengambilan data dilakukan secara daring menggunakan platform kuesioner daring pada bulan November–Desember 2021. Berdasarkan uji statistik deskriptif, 74.4% mahasiswa memiliki tingkat academic hardiness yang tinggi (M = 78.98, SD = 8.767) dengan skor rerata commitment, challenge, dan control yang tinggi pula. Hal tersebut menunjukkan bahwa mahasiswa program studi Profesi Dokter mempersepsikan tuntutan akademik sebagai suatu tantangan yang dapat dijadikan pengembangan diri melalui upaya pengelolaan perilaku selama masa klinik, regulasi emosi, dan keterlibatan personal dengan tugas akademik yang dimilikinya. Dari ketiga dimensi, aspek control memiliki skor rerata tertinggi. Artinya, mahasiswa program studi Profesi Dokter memiliki karakteristik bersedia dan meyakini bahwa dirinya mampu menghadapi tuntutan akademik selama masa klinik dengan usaha mengelola perilaku dan regulasi emosi sebagai proses pembelajaran, sesulit apapun itu.
PENGARUH E-WOM TERHADAP PURCHASE INTENTION MAHASISWA PADA PRODUK BEAUTY BRAND
Authors: Sinurat Abigail Ruth Deborah , Islaha Shafia , Rumiris Michelle Astari , Alfayza Nadira , Azka Putri Nadhira , Erawan Trifena Angelina , Putri Salsabilla Utami
Published: August 2023

Penelitian ini bertujuan untuk melihat apakah terdapat pengaruh dari e-WOM terhadap purchase intention mahasiswi pada produk beauty brand. Penelitian ini menggunakan pendekatan kuantitatif eksperimental dengan rancangan between participant pre-test dan post-test. Digunakan alat ukur dari Iswara dan Jatra (2017) untuk mengukur purchase intention dengan dasar teori Schiffman dan Kanuk (2007). Pengambilan sampel menggunakan teknik convenience sampling dengan jumlah 116 partisipan. Melalui uji Wilcoxon, didapatkan bahwa tidak terdapat perbedaan yang signifikan (z = -2,160, p = .31) antara skor purchase intention yang diberikan partisipan kelompok kontrol pada pre-test (M = 12.69, SD = 3.51) dan post-test (M = 13.22, SD = 3.61). Namun, terdapat perbedaan yang signifikan (z = -4,927, p < .05*) antara skor purchase intention yang diberikan partisipan kelompok eksperimen pada pre-test (M = 12.62, SD = 3.79) dan post-test (M = 14.55, SD = 3.59). Hal ini mengimplikasikan bahwa terdapat pengaruh dari e-WOM terhadap purchase intention mahasiswi pada produk beauty brand.
Hubungan Perceived Social Support dengan Death Anxiety pada Lansia di Panti Sosial Werda Wilayah Cirebon
Authors: Angraeni Yenni , Pebriani Lucia Voni , Noer Afra Hafny
Published: August 2023

Garis pemisah antara usia dewasa menengah dan lansia adalah usia 60 tahun. Pada usia ini, banyak terjadi penurunan, baik penurunan fisik, kognitif, maupun psikologis yang memicu masalah psikologis, salah satunya death anxiety. Death anxiety merupakan pemikiran dan perasaan yang tidak menyenangkan bagi seseorang tentang kematiannya. Pada usia lanjut, social support menjadi hal yang sangat penting untuk membantu menghadapi penurunan berbagai aspek yang terjadi pada lansia. Perceived social support adalah penilaian kognitif bahwa seseorang terhubung dan mendapatkan dukungan dari orang lain. Adanya support dari keluarga dapat membantu lansia menghadapi masalahnya. Rancangan penelitian yang digunakan adalah penelitian korelasional. Teknik pengambilan sampel yang digunakan dalam penelitian ini adalah probability sampling dengan teknik single-stage cluster sampling. Responden penelitian ini berjumlah 30 orang lansia yang berada di panti werda. Instrumen yang digunakan adalah Death Anxiety Scale (DAS) dan Multidimensional Scale of Perceived Social Support (MSPSS). Hasil penelitian menunjukkan mayoritas responden memilki death anxiety pada kategori sedang (73.3%) dan perceived social support pada kategori rendah (73.3%). Uji korelasi Pearson menunjukkan bahwa tidak terdapat korelasi yang searah dan signifikan (r = -.111, p = .560) antara perceived social support dengan death anxiety. Hal ini kemungkinan terjadi karena adanya faktor lain yang lebih berhubungan dengan death anxiety, yaitu ibadah dan kegiatan keagamaan. Kemudian berdasarkan uji beda independent sample t-test dan uji ANOVA, terdapat perbedaan yang signifikan pada kegiatan kelompok keagamaan/sosial dan social support yang diterima lansia terhadap death anxiety.
criminalização da homotransfobia pelo Supremo Tribunal Federal
Authors: Niero Luane Trentin , Puhl Eduardo
Published: August 2023

Considerando-se o caso da criminalização da homotransfobia pelo Supremo Tribunal Federal, o presente artigo objetiva verificar a necessidade de proteção legal para os grupos atingidos e discriminados, aqui descritos como Lésbicas, Gays, Bissexuais e Transgêneros, além de identificar e discutir acerca dos requisitos para criação de um tipo penal e analisar a decisão do Supremo Tribunal Federal (STF) sobre a criminalização do tema. O trabalho se utilizou de um método dedutivo, apoiado em técnicas de revisão bibliográfica e análise da legislação brasileira e da jurisprudência. Verificou-se que, idealmente, a homotransfobia deveria ser criminalizada via legislação ordinária, de competência exclusiva do poder legislativo, sendo que a atuação do STF se configura como ativismo judicial.
A alienação parental inversa sob a ótica dos tribunais
Authors: Silveira Karin de Cássia Damaso da , Borguezan Danielly
Published: August 2023

O presente artigo busca trazer discussões a respeito do instituto da alienação parental inversa na atualidade, realizando buscas na jurisprudência sobre sua aplicabilidade. O objetivo do trabalho é pesquisar sobre o instituto da alienação parental inversa, tendo como problema norteador saber se é possível aplicar o instituto da alienação parental inversa sob analogia das categorias de vulnerabilidades. A metodologia do trabalho terá como objetivo ser uma pesquisa exploratória, de natureza quantitativa, tendo como coleta de dados as de revisão bibliográfica e documental, ou seja, através de consultas nas jurisprudências dos Tribunais dos estados de Santa Catarina e Rio Grande do Sul e também através da página do Superior Tribunal de Justiça. Tais métodos visam contribuir com a pesquisa a fim de que se tragam exemplos reais da aplicabilidade de tal formato de alienação, bem como também o posicionamento dos tribunais frente a alienação parental inversa. Os resultados encontrados nas bases de dados evidenciam que tal instituto é aplicado por analogia a alienação parental, considerando a pessoa idosa como um ser pertencente a categoria de vulnerabilidade, tal qual a criança e o adolescente. No entanto, no que tange aos processos existentes em andamento acerca da temática da pesquisa, poucos são os julgados sob essa ótica do direito, evidenciando assim a ausência de jurisprudência e também de posicionamento do superior sobre a aplicação do instituto da alienação parental inversa.