bluuebunny/crossref_metadata_2025 huggingface dataset:
PLUS-Model Based Multi-Scenario Land Space Simulation of the Lower Yellow River Region and Its Ecological Effects
Authors: Lu Chang , Qi Xiao , Zheng Zhongsen , Jia Kun
Published: June 2022

The rapid urbanization in recent years as a vehicle for social growth and ecological construction has resulted in a significant transformation of the spatial structure of the land in the lower reaches of the Yellow River. Based on this, the current study used the PLUS model to simulate the future territorial spatial pattern of the lower reaches of the Yellow River in various development scenarios to reveal differences in the ecosystem’s spatial distribution and provide a reference for optimizing territorial spatial usage and ecological protection. The results show that the overall accuracy of the Patch-generating Land Use Simulation (PLUS) model’s simulation results was 0.748, the Kappa coefficient was 0.812, and the simulation effect was good. The simulation results for each land space in various situations reveal a preferential spatial development trend model. In the territorial and spatial priority scenario, development was reasonably balanced, which is consistent with the status of the quantitative structure of the territorial space of the study area during 2015. From 2015 to 2035, the value of ecosystem services will change in different ways depending on the scenario and the set priorities. The ecosystem service value decreased in the production space and living space priority development scenarios, while it increased in the ecological space and national space priority development scenarios. The PLUS model has a high degree of applicability to the spatial pattern development simulation of the lower Yellow River region, and the results of this multi-scenario simulation and ecological environmental effect study may be used as a reference for future territorial spatial planning and policy formulation in the region.
The Half-Truth Effect and Its Implications for Sustainability
Authors: Barchetti Alberto , Neybert Emma , Mantel Susan Powell , Kardes Frank R.
Published: June 2022

Misinformation on sustainability has become a widespread phenomenon in many different contexts. However, relatively little is known about several important determinants of belief in misinformation, and even less is known about how to debias that belief. The present research proposes and investigates a new effect, the half-truth effect, to explain how message structure can influence belief in misinformation. Two survey-based experiments were conducted to show that people exhibit greater belief in a false claim when it is preceded by a true claim, even if the two claims are logically unrelated. Conversely, when a false claim is presented before the true claim, it reduces the belief in the entire statement. Experiment 1 shows the basic half-truth effect. Experiment 2 investigates an individual difference, propensity to believe meaningless statements are profound, which impacts the half-truth effect. Both experiments also investigate debiasing of the false information. The results of the experiments were analyzed using analysis of variance and regression-based mediation analysis. Results show that belief in misinformation is dependent on message structure, and show that the order in which true and false elements are presented has a strong influence on belief in sustainability misinformation. Finally, we present a discussion of how policy makers can use these findings to identify those people who are most likely to be swayed by the misinformation, and then design responses to debias sustainability misinformation.
Fiber-Based Masks and Respirators: Using Decontamination Methods and Antimicrobial Treatment to Improve Its Reusability during Pandemic
Authors: Song Xinyu , Liu Pengyan , Yu Liangmin , Zille Andrea
Published: June 2022

Shortage of personal protective equipment (PPE) is often projected in response to public health emergencies such as infection outbreaks and pandemics. Respiratory protective devices (RPDs), namely medical face masks and respirators, are considered the last defense for the front-line healthcare workers. Cleaning, decontamination and reuse of the disposable RPDs have been accepted by local health authorities during the pandemic period. To contribute to the mitigation of RPD shortage and ensure the safe adoption of decontamination protocols, this review discusses the regulated testing standards and the most commonly studied decontamination methods in the literature. The reuse of RPDs must fulfill three criteria: remove the microbial thread, maintain original function and structural integrity (including fitting tests) and leave no harmful residuals. Decontamination methods such as ultraviolet germicidal irradiation, moist heat and vaporized hydrogen peroxide appeared to be the most promising methods in balancing the above-mentioned criteria. However, the effectiveness of decontamination methods varies depending on the RPDs’ models, materials and design. Therefore, the adoption of protocols needs to be evidence-based with full validation in the local institutes. Additionally, new technology such as antimicrobial treated PPE that can reduce the risks of fomite during donning and doffing process with an extended lifespan should be encouraged. Overall, good training and guidance for appropriate reuse of RPDs are fundamental to ensure their efficiency in protecting front-line healthcare workers.
Differential Impacts of COVID-19 on College Student Tourism Jobs: Insights from Vacationland-Maine, USA
Authors: Dangi Tek B. , Michaud Tracy , Dumont Robyn , Wheeler Tara
Published: June 2022

The COVID-19 pandemic has adversely affected all sectors including educational institutions transitioning from face-to-face to hybrid and virtual classes. Partial or full closure of tourism businesses has impacted college students’ jobs within the college and/or outside in the business sector. For a tourism dependent economy such as Maine’s, the impacts of COVID-19 have been severe, including lost job opportunities for students. Several studies have researched the impacts of COVID-19 on the physical, psychological, social, and mental health status of college students; however, few have addressed the impacts on college students’ jobs. Thus, the purpose of this study is to understand how students at the University of Southern Maine (USM) have been impacted in their jobs by COVID-19 and to consider what stakeholders can do to support and rebuild the workforce. A quantitative survey was distributed to all USM undergraduate students (completed by 160) between 26 April through 6 May 2021. The study found that pre-COVID, 44% of student employment was in non-tourism, 25% in tourism, and 16% in USM work study, while 15% were unemployed. At the time of the survey, those proportions had shifted to 42% in non-tourism, 22% in tourism, 14% in USM work study, and 22% not employed with a significant increase in the non-employed student category. The study found that, initially, COVID-19 had impacted student employment in terms of changed responsibilities, reduced hours, job layoffs/losses, increased hours, and voluntary job loss. Students’ current jobs (during the survey) were impacted in the form of changed responsibilities/jobs/locations and industries, including decreased hours. During the pandemic, students valued industry support such as enhanced cleaning/safety, flexible hours/time off, work from home, as well as academic support in terms of flexibility, emotional support, industry updates, and networking opportunities. The study recommends that stakeholders develop collaborative comprehensive emergency management plans (CEMPs) to mitigate disruptions such as COVID-19 and be prepared for future disasters of this nature.
Baseline Needs Assessment for a Hospital-Based Violence Intervention Program 1-Year Pilot
Authors: Foje Nathan , Raposo-Hadley Ashley Ann , Farrens Ashley , Burt Jenny , Evans Charity H. , Bauman Zachary M. , Armstrong Gaylene , Foxall Mark , Garman Julie
Published: June 2022

The objectives of the present study were to measure and describe the baseline participant needs of a hospital-based violence intervention 1-year pilot program, assess differences in expected hospital revenue based on changes in health insurance coverage resulting from program implementation and discuss the program’s limitations. Methods: Between September 2020 and September 2021 Encompass Omaha enrolled 36 participants. A content analysis of 1199 progress notes detailing points of contact with participants was performed to determine goal status. Goals were categorized and goal status was defined as met, in process, dropped, or participant refusal. Results: The most frequently identified needs were help obtaining short-term disability assistance or completing FMLA paperwork (86.11%), immediate financial aid (86.11%), legal aid (83.33%), access to food (83.3%), and navigating medical issues other than the primary reason for hospitalization (83.33%). Conclusions: Meeting the participants’ short-term needs is critical for maintaining their engagement in the long-term. Further, differences in expected hospital revenue for pilot participants compared with a control group were examined, and this analysis found a reduction in medical and facility costs for program participants. The pilot stage highlighted how complex the needs and treatment of victims of violence are. As the program grows and its staff become more knowledgeable about social work, treatment, and resource access processes, the program will continue to improve.
A Neighborhood-Level Analysis of Low-Income Housing Tax Credit Developments in the State of California and Los Angeles County
Authors: Basolo Victoria , Huarita Edith , Won Jongho
Published: June 2022

Some housing researchers have criticized the United States housing subsidy scheme referred to as the Low-Income Housing Tax Credit (LIHTC) program for failing to promote better opportunities for low-income persons. In this study, therefore, we examine the socio-economic and built-environment characteristics of LIHTC developments at the neighborhood level. Specifically, we aim to investigate the characteristics associated with LIHTC developments compared to neighborhoods without this kind of development. We focus on California statewide initially and then narrow our focus to examine LIHTC developments in Los Angeles County (LAC). We then compare the results from the two levels of government. We compiled data from several sources including the U.S. Census Bureau, the State of California, the Southern California Association of Governments, and other secondary sources; used Geographic Information Systems (GIS) to aid in creating several location-based indicators; and employed logistic regression for analyses. Our results show that LIHTC developments at the statewide and county levels tend to be in racially/ethnically diverse neighborhoods with higher levels of economic hardship, lower rents, a higher percentage of renters, and spatial clustering of LIHTC developments. With LAC removed from the state-level analysis, economic hardship is not more likely to occur in LIHTC neighborhoods. This finding suggests, except for in LAC, state policies may be having some level of success in locating LIHTC housing outside of hardship areas. Finally, in examining additional built-environment variables in LAC, we find LIHTC developments were more likely to be in a neighborhood with a park than other neighborhoods in the county. We discuss these results further and conclude with a brief recap of results, policy recommendations, and suggestions for future research.
Bis-Benzylisoquinoline Alkaloids Inhibit Porcine Epidemic Diarrhea Virus In Vitro and In Vivo
Authors: Dong Shijuan , Yu Ruisong , Wang Xiaoting , Chen Bingqing , Si Fusheng , Zhou Jiaming , Xie Chunfang , Li Zhen , Zhang Daojing
Published: June 2022

Porcine epidemic diarrhea virus (PEDV) belongs to the genus Alphacoronavirus of the family Coronaviridae that causes severe diarrhea and high mortality in neonatal suckling piglets. Currently, there is no effective medication against this pathogen. Cepharanthine (CEP), tetrandrine (TET), and fangchinoline (FAN) are natural bis-benzylisoquinoline alkaloids with anti-inflammatory, antitumor, and antiviral properties. Here, we first found that CEP, TET, and FAN had anti-PEDV activity with IC50 values of 2.53, 3.50, and 6.69 μM, respectively. The compounds could block all the processes of viral cycles, but early application of the compounds before or during virus infection was advantageous over application at a late stage of virus replication. FAN performed inhibitory function more efficiently through interfering with the virus entry and attachment processes or through attenuating the virus directly. CEP had a more notable effect on virus entry. With the highest SI index of 11.8 among the three compounds, CEP was chosen to carry out animal experiments. CEP in a safe dosage of 11.1 mg/kg of body weight could reduce viral load and pathological change of piglet intestinal tracts caused by PEDV field strain challenge, indicating that CEP efficiently inhibited PEDV infection in vivo. All of these results demonstrated that the compounds of bis-benzylisoquinoline alkaloids could inhibit PEDV proliferation efficiently and had the potential of being developed for PED prevention and treatment.
Adult Hepatitis B Virus Vaccination Coverage in China from 2011 to 2021: A Systematic Review
Authors: Bai Xinxin , Chen Lu , Liu Xinyao , Tong Yujia , Wang Lu , Zhou Minru , Li Yanming , Hu Guangyu
Published: June 2022

Background: The most effective way to prevent hepatitis B virus (HBV) infection is vaccination. Synthesized data on vaccination coverage in adults against hepatitis B in China are scarce. We aimed to estimate the hepatitis B vaccination rate in adults in China. Methods: We searched PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure, WanFang, and Sinomed databases for observational studies published between 1 January 2011 and 1 October 2021. Data were extracted using a standardized form to estimate the pooled vaccination coverage rate and 95% confidence intervals (CI) based on inclusion and exclusion criteria. Subgroup analysis was employed to explore heterogeneity. This study is registered in PROSPERO, CRD42021293175. Results: We identified 5128 records, of which 21 articles that included 34,6571 adults. The pooled coverage rate and 95% confidence intervals were 26.27% and 22.73–29.82%, respectively. The pooled coverage rates were 22.06% (95% CI: 15.35–28.78%), 33.81% (95% CI: 28.77–38.85%) and 23.50% (95% CI: 17.37–29.64%) in eastern China, central China and western China, respectively. Furthermore, males had a pooled hepatitis B vaccination coverage rate of 23.47% (95% CI: 15.61–31.33%), whereas, in females, the coverage rate was 26.60% (95% CI: 18.73–34.47%). The pooled hepatitis B vaccination coverage rate in the age group younger than 40 years was 36.93% (95% CI: 28.35–45.50%), while in the ≥40-year-old group, the pooled hepatitis B vaccination coverage rate was 17.09% (95% CI: 10.18–24.00%). The pooled hepatitis B vaccination coverage rate in urban areas (40.29%, 95% CI: 20.91–59.67%) was higher than in rural areas (16.54%, 95% CI: 7.80–25.29%). The average weighted, pooled hepatitis B vaccination coverage rate was 26.53% (20.25–32.81%) in 2011–2015 and 26.12% (22.04–30.20%) in 2016–2021. Conclusions: This systematic review provides the hepatitis B vaccination coverage rate of adults in China (26.27%). The low prevalence of vaccine-mediated immunity among adults in China underscores the urgent need for targeted immunization strategies for vulnerable Chinese adults to ensure progress toward the target of eliminating hepatitis B by 2030.
Predictors of Immunogenic Response to the BNT162b2 mRNA COVID-19 Vaccination in Patients with Autoimmune Inflammatory Rheumatic Diseases Treated with Rituximab
Authors: Furer Victoria , Eviatar Tali , Zisman Devy , Peleg Hagit , Braun-Moscovici Yolanda , Balbir-Gurman Alexandra , Paran Daphna , Levartovsky David , Zisapel Michael , Elalouf Ofir , Kaufman Ilana , Broyde Adi , Polachek Ari , Feld Joy , Haddad Amir , Gazitt Tal , Elias Muna , Higazi Nizar , Kharouf Fadi , Pel Sara , Nevo Sharon , Elkayam Ori
Published: June 2022

Treatment with rituximab (RTX) blunts SARS-CoV-2 vaccination-induced humoral response. We sought to identify predictors of a positive immunogenic response to the BNT162b2 mRNA vaccine in patients with autoimmune inflammatory rheumatic diseases (AIIRD) treated with RTX (AIIRD-RTX). We analyzed 108 AIIRD-RTX patients and 122 immunocompetent controls vaccinated with BNT162b2 mRNA participating in a multicenter vaccination study. Immunogenicity was defined by positive anti-SARS-CoV-2 S1/S2 IgG. We used a stepwise backward multiple logistic regression to identify predicting factors for a positive immunogenic response to vaccination and develop a predicting calculator, further validated in an independent cohort of AIIRD-RTX BNT162b2 mRNA vaccinated patients (n = 48). AIIRD-RTX patients who mounted a seropositive immunogenic response significantly differed from patients who did not by a lower number of RTX courses (median (range) 3 (1–10) vs. 5 (1–15), p = 0.007; lower cumulative RTX dose (mean ± SD) 6943.11 ± 5975.74 vs. 9780.95 ± 7240.12 mg, p = 0.033; higher IgG level prior to last RTX course (mean ± SD), 1189.78 ± 576.28 vs. 884.33 ± 302.31 mg/dL, p = 0.002), and extended interval between RTX treatment and vaccination, 469.82 ± 570.39 vs. 162.08 ± 160.12 days, p = 0.0009, respectively. Patients with ANCA-associated vasculitis and inflammatory myositis had a low likelihood of a seropositive immunogenic response compared to patients with rheumatoid arthritis, odds ratio (OR) 0.209, 95% confidence interval (CI) 0.046–0.96, p = 0.044 and OR 0.189, 95% CI 0.036–0.987, p = 0.048, respectively. Based on these findings, we constructed a calculator predicting the probability of a seropositive immunogenic response following BNT162b2 mRNA vaccination which performed with 90.5% sensitivity, 59.3% specificity, and 63.3% positive and 88.9% negative predictive values. In summary, the predicting calculator could guide clinicians for optimal timing of BNT162b2 mRNA vaccination in AIIRD-RTX patients.
A Testing and Quarantine Algorithm for Individual International Travelers Using Published Data on WHO-Approved Vaccines and Bayes’ Theorem
Authors: Lee FuShiuan Whitney , Wang Jamie , Wang C. Jason
Published: June 2022

Policies such as border closures and quarantines have been widely used during the COVID-19 pandemic. Policy modifications and updates, however, must be adjusted as global vaccination rates increase. We calculated the risks of individual travelers based on their expected transmission and benchmarked them against that of an unvaccinated traveler quarantined for 14 days without testing. All individuals with a negative preboarding test can be released with a negative arrival test, when both tests have a sensitivity ≥ 90% and a specificity ≥ 97%, performance characteristics that could be accomplished by rapid antigen tests. This assumption is valid for an incidence rate up to 0.1 (prior to testing) and effective reproduction number (Rt) up to 4 in the arrival country. In a sensitivity analysis scenario where the incidence rate is 0.4 and Rt is 16, a negative preboarding test and a negative arrival test, both with a sensitivity ≥ 98% and a specificity ≥ 97%, can ensure that a traveler has a lower expected transmission than an unvaccinated person who is quarantined for 14 days. In most cases, fully vaccinated travelers (with or without booster) and a negative preboarding test can be released with a negative rapid antigen test upon arrival, allowing travelers to depart the airport within 30 min.
Changes in the Oxidative Stress Status of Dogs Affected by Acute Enteropathies
Authors: Candellone Alessia , Girolami Flavia , Badino Paola , Jarriyawattanachaikul Watanya , Odore Rosangela
Published: June 2022

Canine acute enteropathies (AE) are common morbidities primarily managed with supportive therapy. However, in some cases, unnecessary courses of antibiotics are empirically prescribed. Recent studies in humans have hypothesized the use of antioxidants as a possible alternative and/or support to antimicrobial drugs in uncomplicated cases. Considering the global need to reduce the antibiotic use, the aim of the study was to compare the oxidative burden of the diarrhetic population to that of healthy dogs. Forty-five patients suffering from uncomplicated acute diarrhea (AD) and 30 controls were screened for clinical and biochemical parameters, and serum redox indices (reactive oxygen metabolites, dROMs; serum antioxidant capacity, SAC; oxidative stress index, OSi). The average levels of dROMs in AD dogs were significantly higher (p < 0.001) than in healthy dogs, while SAC did not significantly differ between the two groups. However, the OSi values (ratio between dROMs and SAC) significantly increased (p < 0.001) in AD dogs compared to controls. The study demonstrates that canine AD could induce redox imbalance. Although its role in the etiopathogenesis and evolution of the disease should be further investigated, our results suggest that the improvement of the patient oxidative status, possibly through the dietary administration of antioxidants, could support the management of canine AE, reducing the use of antibiotics.
Urban Hydrogeology Studies
Authors: Gogu Constantin Radu
Published: June 2022

Urbanization is a pervasive phenomenon of our time, and sustainable urban development is one of the greatest challenges faced by the contemporary world [...]
Relative Sea-Level Changes and Their Impact on Coastal Zones: Past and Future Scenarios from Cases Studies around the World
Authors: Aucelli Pietro P. C. , Mastronuzzi Giuseppe , Mattei Gaia
Published: June 2022

In recent decades, the study of sea-level changes as recorded along entire coastlines around the world has been a primary scientific focus in climate change studies; it allows the exploration of past landscape evolution, geomorphological processes, human impact, and system response to develop future perspectives [...]
Thirty years of land reform (1991–2021)
Authors:   Kazakh Agrotechnical University named after S. Seifullin, Astana, Kazakhstan, Spektor M.D. , Garkushina V.V. ,   Kazakh Agrotechnical University named after S. Seifullin, Astana, Kazakhstan
Published: June 2022

This study analyzes the change in the structure of agricultural land use over the 30 years of land reform in Kazakhstan (from 1991 to 2020). The land reform was aimed at the creation of various forms of management, which created the necessary organizational, economic and social conditions for the development of the agricultural land market. However, it has led to a significant concentration of land in hands of some land owners. To confirm this hypothesis, comparative data collected in Kazakhstan for thirty years were used, starting from the period before the land reform (1991) and up to 2021. A new phenomenon for the Kazakh agricultural economy - peasant and farm enterprises represent an ever-increasing part of agricultural land use. As a result of the reforms, 61.7% of all agricultural land was transferred to peasant and farm usage. The goals of the land reform were to increase the efficiency of land use, create conditions for increasing the social, investment and productive potential of land, turning it into a powerful independent factor in economic growth. These goals were achieved in the process of land reform through a dramatic shift from the predominance of large-scale agricultural holdings (collective and state farms) to individual or family farming based on peasants and farmers. For the period from 1991 to 2020, the number of peasant farms increased by 87 times, and their area by 41 times, and in subsequent years these figures remained at a high level.
The first widespread drawings of church lands in Ruza district of Moscow province as a tool for identification of church property objects
Authors:   State University of Land Management, Moscow, Krasovskiy A.P.
Published: June 2022

The article analyses the possibility of identifying the objects depicted on the first widespread drawings of church lands located on the territory of Ruza district, Moscow province based on the materials received from the Moscow eparchy of the Russian Orthodox Church. The investigation showed that during the 17th century, due to the lack of the possibility of detection, one sixth of the church lands, information about which was contained in the documents, was lost. The systematized list and descriptions of the features of the drawings compiled in the course of the study made it possible to achieve confident identification of church lands lost in times close to the times of creating these cartographic materials, and the possibility of approximate location of the objects depicted on them when performing historical research today.
Remember, honor and be proud of the immortal heroism of the Soviet people in the Great Patriotic War (1941–1945)
Authors:   State University of Land Management, Moscow, Burov M.P.
Published: June 2022

Advisor to the Rector of the State University for Land Management, Doctor of Economics, Professor, member of the Union of Writers of Russia Mikhail Petrovich Burov took part in a Large literary and public competition "Overcoming" in the nomination "Motherland calls" in honor of the Great Victory of the Soviet people in the Great Patriotic War and was awarded the title of laureate with the presentation of the medal of the same name. We publish the text of M.P. Burov's speech.
Fish farming facilities for cultivation in agricultural reservoirs with intense hydrochemical regime
Authors:   All-Russian research Institute of integrated fish farming, a branch of the Federal state budgetary scientific institution “Federal research center for animal husbandry — VIZ named after academician L.K. Ernst”, Servetnik Grigory Emelyanovich
Published: June 2022

Agricultural reservoirs built on acidic, swampy soils, peat processing, as a rule, have a tense hydrochemical regime. Overseas phenomena are also a natural consequence of the intensification of pond fish farming. In the hottest time of the year (most often in July, the first half of August), the massive development of phyto-, zooplankton, benthos and, above all, microorganisms (bacteria), compaction of fish planting for cultivation, intensive feeding with artificial feeds, lead to the accumulation of organic matter and a sharp decrease in oxygen content in water. One of the ways to develop such lands is to expand the number of breeding facilities with increased resilience. Widespread, the most hardy, having high nutritional qualities of fish — golden and silver crucian carp, as well as their hybrids have considerable commercial value in reservoirs of various origins and conditions, especially unfavorable hydrochemical regime. A promising object is the snakehead. This is a predatory freshwater Far Eastern fish, which is characterized by rapid growth and has high-quality meat. It breathes both at the expense of oxygen dissolved in water, and at the expense of atmospheric air, for breathing which it has a gill organ. The snakehead cannot exist only due to water respiration by gills. It feeds at a young age mainly on crustaceans and insects. As they grow, more and more switch to fish food, and large specimens feed almost exclusively on fish and frogs. In reservoirs with a tense hydrochemical regime, due to its unpretentiousness and undemanding to oxygen, tench can be grown. Tench is a promising object for breeding and stocking reservoirs. It is unpretentious, undemanding to water quality, can live in reservoirs with a very low oxygen content (up to 0.3 ml/l), a heavily silted bottom and acidic water, tolerating a decrease in pH to 5.
Psychological weapons as a tool of the West’s hybrid war against Russia (part one)
Authors:   Ulyanovsk State University, Kapkanshchikov Sergey Gennadyevich
Published: June 2022

The article reveals the structure of the leading economic and non-economic tools of the Western countries anti-Russian hybrid war with an emphasis on informational and psychological weapons. The main component of its widespread use in modern Russia is a cognitive weapon aimed at a radical change in the mentality of the population. In the economic sphere, the use of psychological weapons is associated with the widespread penetration of many purely liberal myths into the public consciousness, such as the myths about the unconditional advantages of private property over state property, the expediency of conscious formation of a budget surplus and, accordingly, the persistent accumulation of the National Wealth Fund in the conditions of resources underemployment, the investment of a significant part of international reserves in foreign financial assets, the counteraction to accelerating inflation by pursuing a purely restrictive monetary policy, the need for the full opening of the domestic economy to the outside world. Closely connecting the imposition of such false theories, designed to form a fake reality, with the destructive actions of the "fifth column" of pseudo-liberal national traitors, the author makes proposals aimed at the organizational consolidation of patriotic statist economists in modern Russia.
Development of countryside accommodation facilities in the Russian Federation: problems and prospects
Authors:   eoples’ Friendship University of Russia (RUDN University), Kopytina Elena Valentinovna
Published: June 2022

The development of domestic tourism is impossible without the creation of supporting infrastructure, primarily the necessary number of tourist accommodation facilities. At present, the countryside recreation outside cities in recreational areas, close to natural attractions is an important direction. In this regard, the issues related to the functioning of countryside accommodation facilities are relevant. The article aims to identify key problems hindering the optimal development of countryside accommodation facilities in the Russian Federation and to propose recommendations aimed at their solution. The theoretical basis is the works of domestic authors, analytical data of the Federal State Statistics Service, and the analytical service of the Association of Tour Operators of Russia, Rosagrotourism. General scientific methods and methodological approaches used: analysis, synthesis, system approach. The author of the article analyzes the indicators describing the tourism development in the Russian Federation from 2016 to 2021. The growth of demand for the services of countryside town accommodation facilities has been noted. The key problems hindering the development of the said facilities, including those in rural settlements, are analyzed. Recommendations aimed at solving these problems are provided.The increased demand for tourist services within the country, the need for recreation out of cities in recreational areas, consumer orientation towards eco-accommodation facilities, consuming natural products require the development of a set of measures aimed at the development of countryside accommodation facilities with a wide range of additional services, including agro-leisure activities. The increase in the number of countryside accommodation facilities in Russian regions will contribute to the development of domestic tourism, and redistribution of tourist flow, and will serve as a type of business diversifi cation for farmers and agricultural producers in rural areas.
The impact of the organizational innovation on organizational performance based on the structural equation modeling
Authors:   RUDN University, Russia, Moscow, Xiaoyan Huang
Published: June 2022

The purpose of this study is to explore the impact of the organizational innovation on organizational performance. This paper proposes an initial model of the relationship between organizational innovation, organizational innovation competence and organizational performance through literature discussion and constructs the research hypothesis of this paper. The methodology used in the thesis is elaborated in detail from three aspects: variable measurement, data collection and main analysis methods. This paper puts forward the variable measurement index system. A confirmatory factor analysis and reliability analysis are carried out on related data and variables. The results show that the measures of each variable retained in the model analysis meet the reliability and validity requirements and can be analyzed by structural equation modeling. The main finding of this study: 1. Organizational innovation has a significant positive effect on organizational innovation competence. 2. Organizational innovation has a significant positive effect on organizational performance. Organizational structure innovation has a significant positive effect on organizational performance. Organizational process innovation has a significant positive effect on organizational performance. Organizational cultural innovation has a significant positive effect on organizational performance. Information technology innovation has a significant positive effect on organizational performance. 3. Organizational innovation competence has a significant positive effect on organizational performance. 4. Organizational innovation competence plays a mediating effect between organizational innovation and organizational performance. It proves that organizational innovation needs to improve organizational performance through the accumulation of organizational innovation competence. The conclusions of this study can be applied to innovation and management of manufacturing enterprises.
SERUM ZINC CONCENTRATION OF CORD BLOOD IN TERM NEONATES AT OF HUE UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL
Authors: Ha Phuong Anh , Nguyen Thi Cu , Pham Vo Phuong Thao , Le Mai Anh , Do Ho Tinh Tam , Pham Thanh Mai
Published: June 2022

Background: Zinc is one of the important trace elements involved in many biological functions of the body. Newborns are susceptible to zinc deficiency. Zinc deficiency in the mother during pregnancy can affect the status of zinc supply for the fetus. 70% is accumulated in the last trimester of pregnancy, so term neonates, especially premature neonates are at high risk of zinc deficiency. Several studies have shown that neonates zinc intake is related to maternal serum zinc status during pregnancy; there is a relationship between cord blood serum zinc concentration and birth weight, gestational age. Objectives: To investigate the serum zinc concentration of cord blood and examine several related factors. Materials and methods: Cross-sectional description on 244 umbilical cord blood samples from a mother-child pair of term term neonates born at the Department of Obstetrics and Gynecology, Hue University of Medicine and Pharmacy during the period from
January, 2019 to December, 2019. Results: The median cord blood serum zinc concentration in term neonates was 8.0 (3.8 – 12.0) μmol/l. The rate of zinc deficiency in cord blood was 64.3%. The median umbilical cord blood serum zinc concentration in small for gestational age (SGA) neonates was 2.9 (0.0 – 5.9) μmol/l, in appropriate for gestational age (AGA) neonates was 8.3 (4.2 – 12.2) μmol/l. 100% of SGA neonates have umbilical cord blood serum zinc deficiency. There is a relationship between cord blood zinc concentration and birth weight and length. There was no association between cord blood serum zinc concentration andsex, risk of neonatal infection, maternal disease, or fetal distress. Conclusion: The rate of zinc deficiency in cord blood is very high at 64.3%. Factors related to umbilical cord blood zinc concentration in term neonates were birth weight and length.
Key words: zinc, umbilical cord blood, full-term newborn.
ROLE OF CORD BLOOD BILIRUBIN IN THE PREDICTION OF PATHOLOGICAL HYPERBILIRUBINEMIA IN PRETERM INFANTS
Authors: Nguyen Thi Thanh Binh , Phan Hung Viet
Published: June 2022

Background: Neonatal hyperbilirubinemia is a common clinical problem. Approximately 60% term babies and 80% preterm babies will develop clinically apparent jaundice encountered during the first week of life. Excessive indirect bilirubin concentration can cross the blood-brain barrier and result in death or other severe neurological sequelae. Objectives: To determine the value of cord blood bilirubin to predict pathological hyperbilirubinemia in preterm. Materials and method: A prospective cohort study was carried out on 122 neonates under 37 week at Hue University of Medicine and Pharmacy Hospital, Hue, Vietnam from 4/2018
to 8/2020. Cord blood bilirubin was estimated after birth. Neonates were followed up daily for 7 days for hyperbilirubinemia. Serum bilirubin levels in peripheral blood were estimated from 24 to 36 hours after birth and when the baby developed clinical jaundice. Results: Cord blood bilirubin is a fairly predictor of pathological hyperbilirubinemia in preterm with AUC (95%CI) 0.752 (0.667-0.837). When level of total cord bilirubin is higher than 35.6 μmol/L, preterm babies developed pathological hyperbilirubinemia with a 43,3% sensitivity and 96.4% specfically and +LR 11.9. Conclusion: Cord blood bilirubin may help predict pathological hyperbilirubinemia in preterm
Key words: Neonate, preterm, hyperbilirubinemia, cord blood bilirubin.
DRUG COST OF OUTPATIENT TREATMENT FOR HYPERTENSION AT HUE UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL
Authors: Luu Nguyen Nguyet Tram , Nguyen Duy Phuc , Tran Xuan Thinh
Published: June 2022

Background: Hypertension is a common disease in the world as well as in Vietnam, a great threat to human health. With the number of people suffering from hypertension constantly increasing, the cost of treatment for this chronic disease is a dilemma that not only affects patients directly, but also a burden to society. The study was conducted to contribute to the analysis of the current outpatient drug costs for hypertensive patients. Materials and method: Conducted restropective study. Data was collected outpatient drug payment information for hypertensive patients in 2018. There were 1805 outpatient treatment sessions from 1-6/2018 included in the analysis. Results: The average drug cost of an outpatient treatment course for hypertension is 339,088 ± 257,021 VND. Imported drugs accounted for 80.69% of the total cost and 90.48% of the outpatient treatment course. The cost of antihypertensive drugs accounted for 38.21% of the total drug cost, and the drugs with the highest cost were brand-name drugs. Conclusion: The average drug cost of the treatment course of hypertensive patients with complications/comorbidities was significantly higher than that of patients with hypertension alone. Imported drugs and brand-name drugs account for a large
proportion of drug costs for hypertensive outpatients.
Key words: drug cost, hypertension, outpatient, Hue University of Medicine and Pharmacy Hospital.
EVALUATING MEDICATION ADHERENCE BY MORISKY SCALE AND ADVISORY EFFECTION IN PATIENTS WITH TYPE 2 DIABETES MELLITUS IN HUE UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL
Authors: Le Chuyen , Tran Thi Thuy Nhi , Ngo Thi Kim Cuc , Le Thi Thanh Tinh , Nguyen Thi To , Nguyen Thi Hai Yen
Published: June 2022

Introduction: Good glycemic control is the most important factor in treatment of diabetes. Medication adherence in diabetes is crucial to achieve optimal glycemic control. Objectives: To evaluate the medication adherence by the Morisky Medication Adherence Scale (MMAS-8) and the effectiveness of counseling in patients with type 2 diabetes. Methods: The longitudinal descriptive study was conducted with 396 patients diagnosed of type 2 diabetes mellitus during 2019 - 2020 at Hue University of Medicine and Pharmacy. Interviewing patients with questionnaires, advising medication adherence (according o Treatment principles for diabetic patients - “Guidelines for diagnosis and treatment of type 2 diabetes” of the Ministry of Health); and The Morisky Medication Adherence Scale (MMAS-8) was used to assess the patients’adherence of treatment at the beginning of the study and reevaluated after 3 months. Results: The mean age of the patients was 66.28 ± 14.08 years; 68.7% females. At baseline: 36.6% of patients were nonadherent. After 3 months, 26.3% of patients were non-adherent. Factors affecting the patients’ compliance level was statistically significant: Physical activity (p = 0.009); diet (p = 0.039); reminders of medication adherence from health officer (p = 0.042); satisfied with medical services (p = 0.022). At baseline: 19.2% of patients achieved good glycemic control (6.3 ± 0.8 mmol/l), 22.0% of patients with HbA1c reached target of treatment (6.4 ± 0.4%). After 3 months: 29.0% of patients achieved good glycemic control (6.1 ± 0.9 mmol/l), 33.3% of patients with HbA1c reached target of treatment (6.3 ± 0.4%). The proportion of patients achieved blood glucose and HbA1c targets at baseline and after 3 months was related statistically significant with medication adherence level (p<0.05). Conclusions: Relevant glycemic control was statistically significant with medication adherence. Improving patients’ medication adherence may improve glycemic control. In order to improve medication adherence better, good consultation counseling and health education are required.
Key words: Type 2 diabetes, Medication adherence, Morisky Medication Adherence Scale
EVALUATION OF THE LONGTERM RESULTS OF PERIODONTAL TREATMENT ON PERIODONTAL INDEX AND HBA1C IN TYPE 2 DIABETES PATIENTS
Authors: Nguyen Van Minh , Ta Anh Tuan , Hoang Tu Hung
Published: June 2022

Background: Diabetes mellitus and periodontitis are common diseases, there is a two-way relationship between oral health and systemic disease. Periodontal treatment improves glycosylated hemoglobin.In contrast, glycaemic control can make periodontal status better. Aim: The aim of the study was to evaluate the long-term results of periodontal treatment on clinical features and HbA1c in type 2 diabetes patients. Materials and Methods: A clinical trials study on 76 type 2 diabetes patients with mild and moderate periodontitis. Patiens were divided into two group. Scaling and root planning with Diode laser (SRP+DL) group: full-mouth SRP with Diode laser and Scaling and root planning (SRP) group: full-mouth SRP. Periodontal index and HbA1c were recorded at baseline and six month after treatment. Results: After 6 months, significant changes in periodontal index (p<0.01). HbA1c levels did not change significantly in both groups (p>0.05). Conclusion: The study shows that non-surgical periodontal treatment with/without diode laser change significantly periodontal health, but long-term result do not change HbA1c in type 2 diabetes patients
Key words: type 2 diabetes mellitus, periodontitis, HbA
THE RESULTS OF PAROTID GLAND TUMOR TREATMENT AT HUE UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL
Authors: Hoang Minh Phuong , Tran Tan Tai , Nguyen Hong Loi , To Thi Loi , Hoang Vu Minh , Vo Khac Trang , Nguyen Van Minh , Vo Tran Nha Trang
Published: June 2022

Background: Salivary gland tumors are the most complex and diverse of any organ in the body. Surgery is the mainstay of treatment for salivary gland tumor. Assessing the results of parotid gland tumor treatment is the aim of the study. Objective: To evaluate the results of parotid gland tumor surgery. Materials and Methods: 31 patients with parotid gland tumor who were examined at Hue University of Medicine and Pharmacy Hospital from June 2019 to June 2020 were recorded about clinical, paraclinical and evaluated results at 1 week, 1 month and 3 months after surgery. Results: Histopathological study of parotid salivary gland tumors: pleomorphic adenoma (64.5%), warthin tumour (32.3%), oncocytoma (3.2%). After parotid surgery, cervicofacial branches being the most commonly affected (29%). The most common complication was numbness around the earlope (77.4%), facial paralysis (41.9%), hemorrhage (29.1%), seroma (3.2%) and salivary fistula (3.2%). Conclusion: After performing parotid surgery, facial nerve injury was temporary
Key words: Parotid gland, parotidectomy, facial paralysis
A SURVEY ON THE PERIODONTAL STATUS OF PATIENTS WITH CORONARY ARTERY DISEASE AT HUE UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL
Authors: Tran Tan Tai , Nguyen Thi Thuy Hang , Nguyen Minh Quan
Published: June 2022

Background: The relationship between periodontal disease and coronary artery disease has been suggested for more than a century. This study was carried out with the goal of surveying periodontal status in patients with coronary artery disease and understanding the relationship between periodontal status and severity of coronary artery disease. Subjects and methods: The study was conducted on two groups, including 50 patients with coronary artery disease, compared with control groups of the same age, sex. All subjects had a clinical dental examination to assess the periodontal indicators. Assessment of severity through coronary angiography in the group of diseases, thereby determining the relationships and correlations. Results: In the disease group, the average plaque index (1.96 ± 0.64), gingival index (1.49 ± 0.47) and clinical attachment
loss (2.68 mm ± 1.12) was statistically significantly higher than the control group (p < 0.05). There was no difference in the periodontal pocket depth index between the two groups (p<0.05). The difference in the degree of gingivitis between the two groups was statistically significant (p<0.05). The average of periodontal indexes gradually increased according to the degrees of coronary artery stenosis (p<0.05).There is a significantly moderate positive correlation between the degree of coronary artery stenosis and the degree of periodontitis. Conclusions: There is an relationship between periodontal status and severity of coronary artery disease. Recognizing this relationship, we need to take measures to change people’s awareness about oral health with coronary heart disease through periodic dental examination and treatment
Key words: Periodontal disease, coronary artery disease, relationship
TREATMENT COST OF ROAD TRAFFIC ACCIDENT IN VICTIMS WITH SURGICAL INTERVENTION AT DANANG HOSPITAL
Authors: Nguyen Hoang Lan , Phan Van Lien
Published: June 2022

Objective: To analyze treatment cost of road traffic accident in victims with surgical interventions at Danang hospital on perspective of payers and to identify some factors affecting out of pocket cost of victims and their households. Materials and Method: This is a cross sectional and descriptive study. 193 victims or their relatives were interviewed directly and medical records and invoices were reviewed to collect data of their treatment costs at hospital. Multivariate linear regression model was used to identify factors affecting out of pocket cost of participants. Results: Economic total cost of road traffic accident victims who suffered surgical intervention at Danang Hospital was 28,475 thousand VND, in which medical direct cost, non-medical
direct cost and indirect cost were accounting for 69.8%, 13.6% and 16.6%, respectively. Cost for surgery, medication and hospital bed accounted for the highest proportions of medical direct cost with 33.3%; 25.5% and 18%, respectively. Out-of pocket average total cost was 9,154 thousand VND. Factors influenced their out of pocket cost including participating in health insurance (B= -9,865,109; 95% CI: -12,960,181 - -6,770,038), number of inpatient days (B= 882,125; 95% CI: 780,081- 984,169) and being students (B= 4,081,835; 95% CI: 883,645- 7,280,025). Conclusion: Treatment cost for road traffic accident victims with surgery is economic burden to them and their household.
Key words: road traffic accident, economic cost, economic burden, ability to pay, victim.
UMA LEITURA EQUILIBRISTA SOBRE A FORMAÇÃO DE ALUNOS-LEITORES EM UM 2ºANO DO ENSINO FUNDAMENTAL
Authors: Estanislau Daniele Aparecida Biondo , Baptista Karen Cezar , Silva Giovana Roldão
Published: June 2022

Nos limites deste texto analisaremos práticas de leitura e escrita em uma turma de 2º ano do ensino fundamental para tecermos reflexões entre os modos como eles vivenciam o processo de alfabetização mediado pela leitura de literatura contribuindo para a discussão da formação do sujeito leitor.