bluuebunny/crossref_metadata_2025 huggingface dataset:
Alles wird erledigt!
Authors: Wolff Jurgen , Falkenroth Christoph
Published: February 2025

Aufgaben vor sich herschieben - das kennt wohl jeder. Doch was hilft, um motiviert und zügig To-Dos zu erledigen?

Jurgen Wolff und Christoph Falkenroth stellen dazu in ihrem Buch Methoden vor, die dabei helfen, Aufgaben richtig auszuwählen, das Tagespensum realistisch einzuschätzen und Prokrastination zu vermeiden. So wird nicht nur alles geschafft, sondern es bleibt auch noch Zeit übrig.

Im ersten Teil widmen sie sich der inneren Einstellung und der Auseinandersetzung mit dem destruktiven inneren Kritiker - denn nur mit der richtigen Einstellung lassen sich Dinge zeitsparender erledigen. Anschließend erklären sie ausführlich die korrekte Anwendung hilfreicher Werkzeuge, darunter z. B. das 80/20-Prinzip, die Alter-Ego-Strategie sowie Strategien zur Motivationssteigerung und Prokrastinationsvermeidung. Ergänzend dazu erläutern sie Wissenswertes zu den Themen Willenskraft, Arbeit und Pausen sowie zur Kraft des Nein.

Mit zahlreichen Übungen und praktischen Tipps sowie Zusammenfassungen und Quizfragen am Ende der Kapitel.

Ein Buch für alle, die endlich alles erledigen wollen!
Эффективность и безопасность длительной терапии пегилированным ин-терфероном α-2а истинной полицитемии у ребенка
Authors:   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Pshonkin A.V. , Bogdanov A.V. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Plyasunova S.A. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia, Tarakanova A.V. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia
Published: February 2025

Data on the clinical course and treatment of polycythemia vera (PV) in children are extremely limited; the results of any treatment are currently unknown. Authors represent a clinical case report of a PV pediatric patient who has been receiving long-term cytoreductive therapy with pegylated interferon α-2a (PEG-IFN-α2a): 14 y/o male, first visit to the National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev (Moscow, Russia) in Apr., 2017 at the age of 8 y/o with pronounced changes in the hemogram. In the general blood test: an increase in hemoglobin - 175 g/l, hematocrit - 50.3%, erythrocytosis - up to 6.99x1012/l, other indicators were normal. Molecular genetic examination of bone marrow using high-throughput sequencing revealed a somatic mutation of the JAK2 gene c.1849G>T, p.Val617Phe with an allelic load of 30.23%. Based on the examination results, the patient was diagnosed with PV. PEG-IFN-α2a therapy was initiated. In total, the patient has been receiving the therapy for 7 years; according to the results of control examinations, a persistent partial clinical, hematological and molecular response is maintained throughout the treatment period. Mild adverse events were observed against the background of the therapy: grade 2 neutropenia, grade 1 increase in liver transaminases according to CTCAE v5.0. Conclusion: the use of the PEG-IFN-α2a effectively normalizes the clinical and hematological manifestations of PV in children with no significant adverse events of its use recorded so far.
Organizing the intra-hospital transportation of a newborn: the twelve steps to safety
Authors:   Morozov Children’s City Clinical Hospital, Moscow, Russia, Mukhametshin R.F. , Gorev V.V. ,   Morozov Children’s City Clinical Hospital, Moscow, Russia, Volodin N.N. ,   National Scientific and Practical Center for Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev, Moscow, Russia
Published: February 2025

Intrahospital transportation (IHT) of newborns is an integral part of intensive care and nursing of patients in neonatal ICUs and neonatal departments. Transfer within a medical facility ensures the availability of medical technologies required by the patient and is associated with significant risks of deterioration of the condition, potential increase in the need for certain types of therapy and worsening of hospital stage outcomes at the same time. Nevertheless, the newborns’ IHT problematics remains poorly studied. Undeservedly insufficient amount of attention is paid to the standardization of this section of practical healthcare. Meanwhile, modern requirements for the organization of high-quality and high-safety medical care imply the formation of an optimal technology associated with minimalization of all the risks. Authors summarize the available scientific and practical experience in the field of newborns’ IHT organizing highlighting the key points of the process and inviting neonatologists to further discussion on this important problem.
Technomediation as a Means of Constructing Attitudes towards Health and Illness
Authors:   Saratov State Law Academy, Suslov Ivan V. , Grishechkina Natalia V. ,   Saratov State Medical University named after V.I. Razumovsky,
Published: February 2025

This article addresses the issue of technomediation, viewed as a basis for the development of a digital society and a means of constructing new social practices. The authors analyze the role of technology in shaping individuals’ attitudes toward health and illness. Drawing on the theory of technomediation developed within the framework of post-phenomenological approaches (D. Ihde, P. Verbeek), they demonstrate how new biomedical technologies create, modify, and abolish social practices related to health and illness. Emphasizing the orientation of technologies toward personal access to new possibilities, the authors assert that technomediation, as a condition for the production of the social in modern society, possesses the potential to govern and shape new orders at the level of the individual and their lifeworld. Consequently, there arises a necessity to reassess the epistemological theory, practices, and control surrounding the use of technologies.
EVALUATION OF BUSINESS FEASIBILITY AND IMPACT OF LOCAL INNOVATION ON IMPROVING COFFEE QUALITY IN GARUT REGENCY PRODUCTION CENTER
Authors: Suryana Dadan , Tridakusumah Ahmad Choibar , Charina Anne
Published: February 2025

This study aims to analyse the financial feasibility of the ground coffee production business undertaken by coffee farmers and processors by applying local innovations at the cultivation, post-harvest handling, and coffee processing stages in the coffee production centre of Garut Regency. This study used a quantitative approach to provide a comprehensive understanding of the feasibility of the ground coffee business with local innovations applied by coffee farmers and processors in Garut Regency. Local innovations in coffee production include pruning techniques, grafting, solar dryer dome technology for herbal coffee making, the use of local roasting machines, and the utilization of coffee waste into value-added products such as ceramics, organic fertilizer, and dodol. Quantitative analysis of coffee processing business feasibility based on NPV value of Rp 38,394,163, Gross B/C 1.08, Net B/C 1.25, IRR 17.73 percent, payback period 7.7. These results showed that the business carried out by ground coffee processors in the production centre area is feasible. These results of the sensitivity analysis show that an increase in the price of coffee fruit raw materials at a limit of 16.67 percent and a decrease in ground coffee production at a limit of 11.37percent still produces a positive value and the business is still feasible. These results of the switching value analysis explain that the tolerance limit for the increase in the price of coffee fruit raw materials can be tolerated if the rise is no more than 26.66 percent and the decrease in ground coffee production does not exceed 7.023percent if it exceeds within 1 year then the business is not feasible.
PHYSICO-CHEMICAL ANALYSIS OF GINGER OIL EXTRACTION WITH ADSORBED USED COOKING OIL AND ITS UTILIZATION AS TRADITIONAL MASSAGE OIL
Authors: Riyanta Aldi Budi , Amananti Wilda , Nurbaety Nurbaety , Aulia Firda
Published: February 2025

Used oil is a commodity that can be sought to increase its economic value, one of which is used as an absorber of essential oil from ginger. Ginger has essential oils as anti-inflammatory, but the oil obtained is relatively small and volatile so that it reduces the healing effect. Used oil has the potential to be a massage oil and ginger oil adsorbent to be used to treat inflammation. On the other hand, leaf waste can be converted into activated charcoal which is used as an adsorbent for the treatment process of used oil. The aims of this study was to determine the physicochemical properties of used oil obtained from the extraction process of ginger rhizomes with adsorbed used oil. The method used was the treatment of used cooking oil by adsorbing it using activated charcoal from activated leaf waste. Used cooking oil was then used for solvent extraction of ginger oil content to conduct organoleptic tests, physicochemical properties, inflammatory tests and GC-MS analysis to see the content of the resulting used oil. The results showed that the ratio of ginger to adsorbed used cooking oil with the highest anti-inflammatory effect was at a ratio of 1:1 with good organoleptic results, gingerol content of 11.6%, camphene 3.75% and eucalyptol 6.79 resulting in an antiinflammatory effect close to pure ginger oil of 59.18% with a contact time of 4.55 hours and reaction order 1.
SAFEGUARDING INDONESIA'S CASSAVA INDUSTRY: CRITICAL RESPONSE TO SLCMV'S ADVANCE IN SOUTHEAST ASIA
Authors: Setiawan Andree Wijaya , Kusuma Asista Fatma
Published: February 2025

Sri Lankan Cassava Mosaic Virus (SLCMV) has emerged as a significant threat to cassava production in Southeast Asia since its initial detection in Cambodia in 2015, with recent outbreaks in Vietnam and Thailand and its first detection in Australia in 2024. This viral disease, transmitted by the whitefly Bemisia tabaci and infected planting materials, poses a substantial risk to Indonesia's cassava industry. Studies from affected countries demonstrate yield losses of 16-33% and starch content reductions of 22-38% in infected plants. This review analyzes SLCMV's current status and potential impacts on Indonesian cassava production and proposes management strategies based on regional experiences. We identify critical risk factors, including widespread vector presence and informal planting material exchange networks. Recommended preventive measures include strengthening quarantine systems, implementing enhanced surveillance programs, developing rapid diagnostic capabilities, and establishing clean seed certification systems. Our findings emphasize the urgent need for coordinated action to protect Indonesia's cassava industry from this emerging pathogen.
Analysis of Magnesium as A Prognostic Marker for Chronic Kidney Disease at Dr. Wahidin Sudirohusodo Hospital
Authors: Bahri Suryanti , Kartini Ani , Widaningsih Yuyun
Published: February 2025

Magnesium (Mg) is an essential mineral that plays a role in many organ functions, including the kidneys. Magnesium has roles in regulating mitochondrial function, inflammatory processes, immune defenses, heart excitability, and blood pressure. Chronic Kidney Disease (CKD) can disrupt Mg balance and can have an impact on the progression and prognosis of CKD. This study aimed to analyze Mg levels as a prognostic marker for CKD. This was a descriptive retrospective study with a cross-sectional approach. The total sample consisted of 136 subjects with CKD patients, comprising stage I (n=3), stage II (n=2), stage III (n=11), stage IV (n=26), and stage V (n=94) based on the KDIGO classification. According to KDIGO, they were categorized as low risk (n=5), moderate risk (n=11), and high risk (n=120). Magnesium levels were assessed using the colorimetric method. Statistical analysis was performed using SPSS version 25, including the Kolmogorov-Smirnov test, a Kruskal-Wallis test, the least significant difference, and Spearman's correlation test. The cut-off point was determined using the ROC curve. Results were considered statistically significant if p< 0.05. This study demonstrated a significant positive correlation between eGFR values and Mg levels falling into the moderate category (0.2250<R<0.500). Characteristics of research subjects showed that the lowest Mg levels (1.81) were found in high risk prognosis (p<0.001) and stage 5 CKD (1.72) (p<0.001). The optimal cut-off point for Mg levels in CKD patients was 2.40 mg/dL, with a sensitivity of 76% and specificity of 69%. Magnesium levels can be used as a prognostic marker for CKD.
The Galectin-3 Comparison in NSTEMI and STEMI Patients at Dr. Wahidin Sudirohusodo Hospital
Authors: Halimah Halimah , Lopa Amaliyah Tahir , Rauf Darmawati
Published: February 2025

A common cardiovascular ailment called Coronary Artery Disease (CAD) is characterized by plaque buildup in the coronary arteries, leading to impaired blood circulation to the myocardium. Plaque deposits have the potential to occlude the lumen of the coronary arteries partially, and in certain cases, they can lead to complete occlusion. To differentiate between the two conditions, it is imperative to conduct an electrocardiogram (ECG) and assess cardiac biomarkers. Galectin-3, a protein with a molecular weight ranging from 29 to 35 kilodaltons, is among the biomarkers that have been extensively investigated. The expression of messenger RNA for Galectin-3 can be observed within a time frame of 30 minutes following the occurrence of acute myocardial infarction. It reaches its highest level at 24 hours and remains detectable for a duration of up to 14 days. This study aimed to compare the analysis of the Galectin-3 levels in patients diagnosed with STEMI versus NSTEMI. The present study used a cross-sectional research design. A cohort of 70 samples was categorized into two distinct categories, including STEMI and NSTEMI. Exclusion criteria were applied to eliminate patients with jaundice, infections, sepsis, liver cirrhosis, and malignancy. The Enzyme-Linked Immunosorbent Assay (ELISA) method was utilized to assess the serum levels of Galectin-3. The statistical tests employed in the study included the Kolmogorov-Smirnov test, the Mann-Whitney test, and the Kruskal-Wallis test. It is considered statistically significant at p-value <0.05. The patients' average age was 58.8±9.8 years, while the Galectin-3 value ranged from 2.13 to 65.54 ng/mL, with an average value of 20.41±15.66 ng/mL. Patients with Non-ST-Segment Elevation Myocardial Infarction (NSTEMI) had a Galectin-3 level of 20.26 ng/mL, which was lower than the concentration of 20.55 ng/mL observed in patients with ST-Segment Elevation Myocardial Infarction (STEMI). However, statistical analysis revealed that this difference was not statistically significant (p>0.05). There was a significant statistical difference (p<0.05) in the levels of Galectin-3 between those who had a smoking risk factor (17.79 ng/mL) and those who did not (26.12 ng/mL). Galectin-3 levels were found to be elevated among those suffering from CAD. However, this investigation did not find any significant variations in Galectin-3 levels in STEMI and NSTEMI patients.
Demographics, Clinical Features, Laboratory Results Characteristic of COVID-19 Patients at Dr. Wahidin Sudirohusodo Hospital
Authors: Lolongan Calvarica Lun , Esa Tenri , Bahrun Uleng
Published: February 2025

Coronavirus Disease 2019 (COVID-19) has spread throughout the world since 2020. WHO declared COVID-19 as a pandemic. Pandemic status has now ended, but the rapid spread of COVID-19 can be a concern to anticipate a new spike. Various studies and results regarding characteristics of COVID-19 patients such as age, gender, clinical symptoms, and laboratory examination results have been carried out to provide an overview of various factors that can support COVID-19 infection. Based on this, authors are interested in identifying characteristics of COVID-19 patients based on age, gender, origin, education, occupation, dominant symptoms, severity, COVID-19 biomarkers (NLR, CRP, procalcitonin, D-dimer, ferritin), and CT value at Dr. Wahidin Sudirohusodo Hospital as COVID-19 referral center in Eastern Indonesia. This study aimed to determine the characteristics of COVID-19 patients at Dr. Wahidin Sudirohusodo Hospital, Makassar. A descriptive cross-sectional study on 650 COVID-19 patients was performed at Dr. Wahidin Sudirohusodo Hospital, from January 2020–July 2022. The data were described based on age, gender, regional origin, education, occupation, severity (asymptomatic, mild, moderate, severe, and critical), dominant symptoms, laboratory biomarker (NLR, CRP, procalcitonin, D-dimer, ferritin) and CT value. There were more males than females (52.8% vs. 47.2%), age range 26-35 years (20.3%), from South Sulawesi (91.3%), non-PNS (37.1%), and senior high school education was the largest (29.2%). Dominant symptoms were respiratory distress (26.9%) and mild severity (41.7%). Based on the results of COVID-19 biomarker research, it is known that the range of COVID-19 biomarkers differs between mild and critical degrees. In mild degrees, the range of COVID-19 biomarkers is lower than critical degrees. It is known that the range of each biomarker in mild degree NLR 1.02-7.14, CRP 0.20-35.20 mg/l, procalcitonin 0.05-0.75 ng/mL, D-dimer 0.11-1.04 µg/mL, and ferritin 16.15-402,40 ng/mL. Higher COVID-19 susceptibility among males and certain occupational groups. Symptoms vary widely, with some cases showing no symptoms. Disease severity ranges from mild to asymptomatic, with biomarkers indicating progression.
Effect of Vitamin D3 Supplementation on Hepcidin and Ferritin Levels in Children with CKD
Authors: Rachmayani Andi Muldiana Dwi , Aras Jusli , Rauf Syarifuddin , Lawang Aizah
Published: February 2025

Chronic Kidney Disease (CKD), as a worldwide health concern, results in several complications. Anemia caused by erythropoietin deficiency, reduced iron absorption, and abnormalities in vitamin D metabolism are frequently seen in children with CKD. Ferritin is the body's iron storage, whereas hepcidin is a protein that impacts iron metabolism. Low vitamin D levels exacerbate heme deficiency and anemia. This study aimed to know the effect of vitamin D3 supplementation on serum hepcidin and ferritin levels in children with CKD. A prospective cohort design was conducted in Dr. Wahidin Sudirohusodo Hospital from July 2023 to April 2024. Samples were divided into two groups based on GFR. Complete blood count, vitamin D, ferritin, and hepcidin level examinations were performed before and after supplementation. The data was analyzed with the Mann-Whitney test. Forty-three children between the ages of 2 and 18 were involved in this study. There was no significant difference in the groups' age, gender, nutritional status, or diagnosis (p > 0.05). Ferritin levels significantly dropped in group II (p=0.002), hepcidin levels significantly dropped in all subjects (p < 0.001), and vitamin D levels increased significantly in both groups (p < 0.001) following supplementation. Vitamin D supplementation effectively increases vitamin D levels in children with CKD and significantly affects ferritin and hepcidin levels.
Mehrsprachige kompetenzen im hochschulischen kontext aus translingualer perspektive
Authors: Tork Silke
Published: February 2025

Der Artikel präsentiert Ergebnisse einer qualitativen Studie zu Mehrsprachigkeit im hochschulischen Kontext. Basierend auf einem Korpus aus zwei Datensätzen, erhoben an einer nationalen und einer internationalen Hochschule, werden aufgabenorientierte Gruppengespräche mit Verfahren der multimo-dalen Interaktionsanalyse untersucht. Jenseits von Anzahl und Kompetenzniveau der Sprachenkenntnisse zeigen sich mehrsprachige Praktiken und Kompetenzen wie die Aushandlung von Sprachenwahl, sprachliche Ko-Konstruktionen und das Öffnen translingualer Räume.
Myocarditis and pericarditis during COVID-19 pandemic: a study of the Italian Society of Cardiology
Authors: Birtolo Lucia Ilaria , Di Pietro Gianluca , D’Ascenzo Fabrizio , Cuccuru Giuditta , Fabris Enrico , Merlo Marco , Andreis Alessandro , Cameli Matteo , Improta Riccardo , Campo Gianluca , De Ferrari Gaetano Maria , Emdin Michele , Galassi Alfredo Ruggero , Iliceto Sabino , Imazio Massimo , D’Agata Mottolese Biancamaria , Porto Italo , Montisci Roberta , Novo Giuseppina , Pavan Daniela , Vizza Carmine Dario , Maestrini Viviana , Basso Cristina , Perrone Filardi Pasquale , Sinagra Gianfranco , Mancone Massimo
Published: February 2025

Aims

Some studies about myocarditis and pericarditis following COVID-19 vaccination raised concerns worldwide. However, the heterogeneous diagnostic criteria for postvaccination inflammatory heart diseases may result in overestimating incidence rates. The aim of this multicentre Italian registry is to evaluate the impact of COVID-19 vaccines on the incidence of myocarditis and pericarditis in the Italian population.

Methods

Consecutive patients admitted to Italian hospitals for endomyocardial biopsy and/or cardiac magnetic resonance proven acute myocarditis and/or pericarditis in the same period (1 June–31 October) of 2019 and 2021 were enrolled, irrespective of the potential association with the COVID-19 vaccines. Acute pericarditis and/or myocarditis were defined as ‘vaccine-related’ if clinical presentation occurred within 15 days after COVID-19 vaccination, independently of the dose.

Results

There was a comparable incidence rate ratio (IRR) for inflammatory heart diseases in 2019 and 2021 (2019: IRR 0.67 versus 2021: IRR 0.74, P = 0.45). In particular, the IRR did not differ in myocardial involvement (2019: IRR 0.33 versus 2021: IRR 0.33, P = 1) and pericarditis (2019: IRR 0.37 versus 2021: IRR 0.49, P = 0.09) in both periods. Among 125 cases registered in 2021, 32 (25.6%) were ‘vaccine-related’. Among those who experienced ‘vaccine-related’ myocarditis and/or pericarditis, men with age under 40 years were over-represented (53.12%, P = 0.021).

Conclusion

In a nationwide Italian survey comparing pandemic with prepandemic periods, the overall data do not indicate significant concerns about an increased incidence of pericarditis and myocarditis, suggesting that the vaccine is generally well tolerated for these specific conditions.
Critical approach to the 2023 European Society of Cardiology guidelines on cardiomyopathies: a document by the Working Group on Myocardial and Pericardial Diseases of the Italian Society of Cardiology
Authors: Merlo Marco , Pio Loco detto Gava Carola , Perotto Maria , Aimo Alberto , Autore Camillo , Bauce Barbara , Biagini Elena , Cappelli Francesco , Castelletti Silvia , D’Ascenzi Flavio , de Gregorio Cesare , Limongelli Giuseppe , Marzo Francesca , Musumeci Beatrice , Tini Giacomo , Pedrinelli Roberto , Perrone Filardi Pasquale , Sinagra Gianfranco , Imazio Massimo
Published: February 2025

Last year, the European Society of Cardiology (ESC) published the first guidelines to comprehensively address the management of cardiomyopathies.

This document by the Working Group on Myocardial and Pericardial Diseases of the Italian Society of Cardiology aims at highlighting the most relevant messages and novelties introduced by these guidelines for the management of patients affected by cardiomyopathies.

Five main messages are summarized: the key role of the phenotype, the new classification of cardiomyopathies provided in the ESC guidelines, the importance given to new techniques such as cardiac magnetic resonance (CMR) and genetic testing, the newly provided recommendations given on sport activities and finally how the importance of follow-up evaluations is highlighted.

These five main messages are then further analyzed more in depth so as to inform the reader on all the main novelties of the guidelines and to provide a critical approach to this important document.
Road Rescue: Decentralized Cross-Platform Service Orchestration Based on Blockchain for Roadside Assistance Application
Authors: Somvanshi Vinayak , Walavekar Gandharvi , Thakkar Kevin , Kumbhar Yogesh , Deshmukh Neha , Deshpande Kiran
Published: February 2025

Amid the rapid expansion of the vehicular network, the autonomous design of numerous roadside assistance systems, often involving third-party intermediaries, has raised significant concerns about security and reliability. In response, blockchain technology has emerged as a groundbreaking solution, effectively decentralizing these systems and enhancing their dependability and security. The initiative is singularly dedicated to crafting a cross-platform application for roadside assistance, aiming not only to streamline the assistance process but also to empower mechanics to broaden their service horizons. It bifurcates the system into distinct components tailored for mechanics and customers. Programmed in Dart on the Flutter framework, the application seamlessly connects with Firebase as the database, ensuring efficient data management and retrieval. Within this comprehensive application, we have integrated user-centric features, robust data security measures, and real-time service tracking capabilities, all contributing to heightened transparency and user control. Users can request assistance by identifying their precise locations and service requirements, and mechanics can verify their availability, promptly providing clients with well-informed alternatives. The blockchain is intricately connected through endpoints on the cloud, contributing to the overall efficiency of the application. The integration of smart contracts and thorough mechanic verification collectively fortify the reliability and security of the assistance process, establishing a robust foundation for the successful execution of requested services; this not only ensures data integrity and security but also optimizes the performance of the blockchain in facilitating seamless transactions.
Blockchain-Powered Smart System Platform Development: Use Case – Water Meter Readings
Authors: Mohamed Shams Adhouha Ben , Talha Amira , Ktari Jalel , Taleb Youssef Ben , Frikha Tarek , Hamam Habib
Published: February 2025

Today, blockchain technology represents a significant advancement in the field of data management, providing promising opportunities to transform various sectors. Indeed, it offers innovative solutions and builds trust within multi-stakeholder business networks. This article looks at multiple concrete applications of blockchain, highlighting its potential for optimizing water meter reading processes. Moreover, there’s a growing trend toward incorporating Artificial Intelligence (AI) for more accurate and efficient water meter readings. This integration enhances the precision and efficiency of water meter readings, providing valuable insights into water consumption. More specifically, it explores how this technology can be integrated into the development of a dedicated Android application. Thanks to this application, users can now easily and quickly take water meter readings from their smartphone. The data is then secured on the Ethereum blockchain, using smart contracts to guarantee the integrity and transparency of the information recorded. This revolutionary approach opens new perspectives for efficient and secure data management in the field of water resources management.
Ways to Activate the Learning of German as a Second Foreign Language in a Non-Linguistic University
Authors:   Russian Academy of National Economy and Public Administration, Mishin A.
Published: February 2025

The subject of the article is teaching a second foreign lan­guage at a non-linguistic university. The topic of the work is ways to enhance the development of the German language in these circumstances. The purpose of the work is to demonstrate the methods of teaching the German language in conditions of lack of time and low motivation of students. Among the most effec­tive methods of teaching the German language are: independent tasks for composing texts based on familiar lexical units and grammatical rules; tasks to understand the meaning of prefixes and other parts of words in German. The results of the study are the elimination of stereotypes about the German language among students and the emergence of interest in the subject among students. The area of application of the identified meth­ods of activation is the teaching of German as a second foreign language in any areas of a non-linguistic university.
From the Dialogue of Cultures to the International Legal Discourse in Teaching the Russian Language to Inophones
Authors:   Russian State University for the Humanities, Nedosugova A.
Published: February 2025

The modern geopolitical world map, which has undergone a number of historical, economic, social, ethnocultural and other changes, has led to the emergence in the Russian universities of a new foreign students contingent — from neighboring coun­tries owning a certain Russian communicative competence level, namely B2, which is achieved by non-CIS-students only after undergraduate graduation and specialty studies. The new neighboring countries students’ contingent entering Russian universities which train international relations and international law specialists, as a rule, is familiar with Russian culture, traditions, literature, etc., but does not have professional communication skills and appropriate language competence. Consequently, there is a need to develop educational and methodological complexes in Russian language for the above students’ category. The article presents a linguo-didactic model of teaching Russian language to foreign students from neighboring countries, which considers the future international specialists’ subject competence and professional communicative needs.
Implementing Marketing Strategies in EFL Classes in the Age of ‘Clip Thinking
Authors:   MGIMO University, Strelnikova O.
Published: February 2025

The object of the article is new strategies used in EFL classes in the age of ‘clip thinking’. The subject of the article is marketing strategies used in the EFL training. It is suggested that the ‘clip thinking’ of the new generation must be accommodated when making up EFL lesson plans by employing marketing strategies, including commercials, advertisements, and film promotion in­terviews. The purpose of the article is to prove that the above mentioned marketing strategies can provide outstanding listen­ing comprehension material, interesting discussion points and a new perspective of the topics suggested in the textbook. The research uses the empirical method, with classes based on the textbooks for second and third year MGIMO students enhanced by the suggested marketing strategies. The results of the present study demonstrate that these materials can be used to create some additional classroom activities, making EFL classes truly educational.
Electromechanical Integration For Hybrid Solar and Wind Energy Systems: A Case For Maximized Renewable Energy Capture
Authors: Imon Kazi Abdullah Al , Newaz Abdullah Al Hossain , Uddin Nasir , Tanvir Imran Khan
Published: February 2025

Objectives: This research focuses on the development of a novel electromechanical integration mechanism for hybrid solar and wind energy systems to maximize renewable energy capture. The primary goal is to enhance energy conversion efficiency through the combination of optimized electromechanical components. Additionally, the study aims to bridge gaps in existing hybrid energy system designs and integration techniques.
 
Methods: The study begins with an extensive literature review to identify gaps in current hybrid energy system designs and integration strategies. Based on these findings, a novel system architecture is proposed that incorporates advanced electromechanical components. To assess the performance of this proposed system, MATLAB/Simulink and COMSOL are used to model and simulate the hybrid system under various environmental conditions. A small-scale prototype is developed to validate the simulation results and analyze real-world performance. Control systems are also integrated into the design for load balancing, power management, and operational optimization. Additionally, a comprehensive environmental and economic analysis is carried out to evaluate the system's cost-effectiveness and ecological impact.
 
Results: The simulation results demonstrate significant improvements in energy conversion efficiency and system performance compared to existing hybrid energy systems. The small-scale prototype further validates these findings, providing real-world data on energy generation, efficiency, and sustainability. The control systems successfully optimize performance by balancing loads and managing power distribution under different operating conditions. Environmental and economic analyses show that the proposed system is more cost-effective and has a lower ecological impact than current alternatives.
 
Conclusion: The research concludes with a discussion on the key findings, emphasizing the improvements in efficiency, sustainability, and economic viability of the proposed hybrid energy system. The results suggest that the integration of electromechanical components and advanced control systems can significantly enhance the performance of hybrid solar and wind energy systems. Future work will explore further optimization of the system and its scalability for larger applications.
A Perspective of Theory of Reasoned Action and Planned Behavior: Purchase Decision
Authors: Panjaitan Roymon , Cahya Handy Nur
Published: February 2025

This research addresses the inconsistencies in findings related to celebrity endorsers, brand image, and trust level that influence buying interest to drive purchase decisions for the 3Second brand product. The role of buying interest represents a novel aspect of this study, further explored through the Theory of Planned Behavior (TPB) and the Theory of Reasoned Action (TRA). A quantitative approach involved 100 respondents using the 3Second brand products across Central Java, Indonesia. Data analysis was conducted using SEM-PLS software to develop a structural theory by exploring the relationships between constructs based on TRA and TPB theories. The findings indicate that buying interest significantly contributes, directly and indirectly, to leverage consumer behaviour in making purchase decisions influenced by celebrity endorsers, brand image, and trust level. Additionally, the theoretical implications of TRA and TPB highlight that these theories primarily assume individuals are rational in considering their actions and the implications of those actions.
Driving Success in Fast-Fashion Retail: A Moderated Mediation Model
Authors: Widjaja William , Sabil Sabil  , Michael Michael  , Devi Rahnjen Wijayadne
Published: February 2025

This study explores how work stress and participative leadership impact employee motivation in the fast-fashion industry, focusing on 130 employees in the JABOTABEK region. The research employs route analysis and moderated mediation analysis using SMARTPLS, demonstrating that job stress substantially diminishes employee motivation. However, participatory leadership exerts a favourable effect on both motivation and performance. Motivation is a vital intermediary in the correlation between job stress, participatory leadership, and employee performance. Moreover, work satisfaction is a crucial moderator influencing the correlation between motivation and performance. These findings offer theoretical insights and practical consequences for enterprises in the fast-fashion industry. They underscore the need for effective stress management strategies and highlight the importance of participative leadership and job enjoyment in enhancing employee motivation and performance, thereby contributing to improved organisational outcomes.
How to Strengthen Customer Loyalty with Technology
Authors: Pamungkas Charisma , Patiro Shine Pintor Siolemba , Widokarti Joko Rizkie
Published: February 2025

This research aims to investigate the antecedents of loyalty and the role of technology in the Indonesian e-commerce context based on customers' points of view. This quantitative research involves data from 317 Indonesian e-commerce customers, which is then analysed using Structural Equation Modelling with Partial Least Square method (SEM-PLS). The results show customer satisfaction, trust, and engagement significantly impact loyalty. Both Trust and Engagement act as the mediator between Satisfaction and Loyalty. Meanwhile, there are differences in how technology interacts with the equation. While it lessens the influence of Engagement on Loyalty, it will increase the influence of Trust on Loyalty. This research simultaneously adds technology into the model to test its influence on the interaction between variables. It also provides CRM research, which is conducted based on customers' points of view.
Building Homestay User Loyalty with Operational Risk Management Mediated by Satisfaction
Authors: Susanto Dwiyono Rudi , Sugiarto Sugiarto , Kiswantoro Amin , Hendratono Tonny , Priyanto Sony Heru , Budhijono Fongnawati , Rohman Nur
Published: February 2025

Tourists' increasing interest in homestays requires operational risk management for the homestays' sustainability. This study confirms the reliability of homestay operational risk management indicators, tested in Wukirsari tourist village, Yogyakarta, and Dieng tourist village, Central Java. The research respondents were homestay users with experience staying in homestays in both locations. Multi-stage sampling techniques collected data. This mixed-method study used a sequential explanatory design. The structural Equation Model analysed the relationship between Operational Risk Management and Loyalty mediating by satisfaction. Empirical data found that homestay user satisfaction was significantly positively influenced by the performance of operational risk management implemented in homestays in two research locations. It was discovered that satisfaction among homestay users significantly positively influenced their loyalty. Success in satisfying homestay users increases the intention of homestay users to revisit and recommend the homestays they have used to others.
Staurastrum cyclacanthum var. pseudobrevissimus – a new variety of desmids and some other rare taxa found in peat bogs (Western Pomerania, Poland)
Authors: Komarzewska Katarzyna , Kowalski Wojciech W. A.
Published: February 2025

New variety of Staurastrum cyclacanthum var. pseudobrevissimum and four other taxa: Korshikoviella limnetica, Polyedriopsis spinulosa, Monactinus simplex var. echinulatum and Cosmarium sp. rarely reported from the studied region of north-western Poland are noticed. For all of them, detailed descriptions with original documentation and ecological characteristics of the studied sites are presented in this article.
УПРОВАДЖЕННЯ ЗМІШАНОГО НАВЧАННЯ В МУЗИЧНІЙ ОСВІТІ КИТАЮ: ВИКЛИКИ, МОЖЛИВОСТІ ТА ПЕРСПЕКТИВИ
Authors: Чжоу Ань
Published: February 2025

У статті висвітлено досвід впровадження змішаного навчання в музичні навчальні заклади Китаю. Визначено змішане навчання як гібридне онлайн- та офлайн-навчання, як нова тенденція у реформуванні та розвитку музичної освіти Китаю в майбутньому. Зазначено, що успішність впровадження змішаного навчання залежить від створення відповідної інфраструктури, розробки якісного цифрового контенту та забезпечення належної методичної підтримки. Ключовими елементами ефективної реалізації змішаного навчання є спеціалізовані освітні платформи, високоякісні навчальні відео, віртуальні лабораторії та системи онлайн-оцінювання. Описано три етапи впровадження змішаного навчання у музичні заклади. Зроблено висновок, що змішане навчання надає можливість для ефективної інтеграції традиційних та інноваційних освітніх ресурсів, впровадженню інноваційних дидактичних підходів, зокрема  відкриті курси, перевернутий клас та інші. Наголошено що фокус наукових досліджень з проблеми змішаного навчання спрямовано на теоретичні та методичні засади ефективності означеного  підходу.
ХАРАКТЕРИСТИКА ОСНОВНИХ МОТИВІВ ОБРАННЯ АБІТУРІЄНТАМИ ЗАКЛАДІВ ВИЩОЇ ОСВІТИ ПРОФЕСІЙ СОЦІОНОМІЧНОГО ПРОФІЛЮ
Authors: Василенко Олена
Published: February 2025

Стаття присвячена дослідженню основних мотивів обрання абітурієнтами закладів вищої освіти професій соціономічного профілю. Автор статті аналізує такі поняття, як: мотив, мотивація, професійна мотивація, мотиваційна спрямованість особистості. У статті проведено емпіричне дослідження на визначення основних мотивів обрання абітурієнтами закладів вищої освіти професій соціономічного профілю, що дало змогу автору статті зробити висновок, що на цей вибір значний вплив мають такі мотиви, як: соціальні (бажання самовдосконалюватись та саморозвиватися, налагоджувати соціальні контакти, надавати допомогу і підтримку навколишнім); пізнавальні (прагнення до здобуття нових знань і оволодіння навичками з певної професійної діяльності); творчі (творче ставлення до праці і творчий характер самої праці).
Eligibility of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) modulator therapies: cohort of cystic fibrosis registry of Türkiye
Authors: Akgül Erdal Meltem , Nayır Büyükşahin Halime , Şen Velat , Ayzıt Kılınç Ayşe , Çokuğraş Haluk , Doğan Güzide , Yılmaz Aslı İmran , Ünal Gökçen , Serbes Mahir , Altıntaş Derya Ufuk , Arık Elif , Keskin Özlem , Özaslan Mehmet Mustafa , Karcıoğlu Oğuz , Köse Mehmet , Başaran Abdurrahman Erdem , Çakır Eylül Pınar , Canıtez Yakup , Özdemir Ali , Harmancı Koray , Uytun Salih , Eryılmaz Polat Sanem , Hangül Melih , Yüksel Hasan , Özcan Gizem , Korkmaz Pervin , Kılıç Mehmet , Gayretli Aydın Zeynep Gökçe , Çaltepe Gönül , Can Demet , Doğru Sibel , Kartal Öztürk Gökçen , Süleyman Ayşe , Topal Erdem , Özsezen Beste , Hızal Mina , Demirdöğen Ezgi , Ogun Hamza , Börekçi Şermin , Yazan Hakan , Selimoğlu Şen Hadice , Doğan Demir Ayşegül , Çakır Erkan , Şişmanlar Eyüboğlu Tuğba , Emiralioğlu Nagehan , Pekcan Sevgi , Özçelik Uğur , Doğru Deniz
Published: February 2025

Background. Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) variants are essential for determining eligibility for CFTR modulator drugs (CFTRms). In contrast to Europe and the USA, the treatment eligibility profile of cystic fibrosis (CF) patients in Türkiye is not known. In this study we aimed to determine the eligibility of CF patients in Türkiye for the CFTRms.
Methods. The Cystic Fibrosis Registry of Türkiye (CFrT) data was used to determine the age of patients in the year 2021 and the genetic variants they were carrying. Age- and CFTR-variant appropriate modulator therapies were determined using the Vertex® algorithm.
Results. Among a total of 1930 registered patients, CTFR gene analysis was performed on a total of 1841 (95.4%) patients. Mutations were detected in one allele in 10.7% (198 patients), and in both alleles in 79% (1455 patients) of patients. A total of 855 patients (51.7% for whom at least 1 mutation was detected) were eligible for the drugs. The most appropriate drug among genotyped patients was found to be elexacaftor/tezacaftor/ivacaftor for 486 patients (26.4%), followed by ivacaftor for 327 patients (17.7%) and lumacaftor/ivacaftor for 42 patients (2%).
Conclusions. Only half of patients registered in CFrT were eligible for CFTRms, which is a significant difference from the CFTR variant profile seen in USA and Europe. However, access to treatment is hampered for some patients whose genes are not analysed. Further studies in CF populations, where rare mutations are relatively more common, will contribute to the field of CFTR modulator treatments for such rare mutations.
Efficient Algorithm of Real-Time Failure Probability Function Updating
Authors: Guo Yifan , Lu Zhenzhou , Chen Yizhou
Published: February 2025

To match the safety level of a structure in real time with the gradually collected observations, it is necessary to develop an efficient method for updating the failure probability function (FPF). Directly updating FPF requires a time-demanding double-loop framework, where repeated failure probability analysis is involved for the varied observations and distribution parameters. To address the issue, an efficient single-loop method is proposed to update FPF in real time. Firstly, the Bayesian approach is used to construct a single-loop framework, and it only requires one augment failure probability analysis to approximate the prior FPF. Secondly, by separating the observation-related part in FPF updating, the posterior FPF varying with the gradually collected observations can be estimated by sharing the sample of the performance function evaluation for prior FPF. Finally, the Kriging model is adaptively embedded to further enhance the efficiency of the proposed method, and the presented examples verify the high efficiency under acceptable accuracy.
Estimation of Pressure Leakage Severity for Space Habitats Using Extended Kalman Filter
Authors: Mirfarah Motahareh , Lund Alana , Dyke Shirley J.
Published: February 2025

Extraterrestrial habitat systems face numerous disruptions throughout their lifecycle, which may threaten crew safety. One serious risk is associated with air pressure leakage, which can occur due to sudden events such as micrometeorite strikes or airlock failures. To ensure proper functionality of the habitat, it is essential to detect the leak and assess its severity, quantified in terms of the leakage area, and communicate that information to the health management system in a meaningful way to support decision-making. A quantitative prediction of the remaining time before the detected fault results in system failure; its time-to-critical is also helpful for making decisions in such a resource-constrained environment. This paper presents a systematic study to develop and examine methods to estimate the current state of a pressurized vessel and predict the time-to-critical. To achieve this estimate in a real-time setting, an augmented extended Kalman filter method is used in conjunction with two noise identification procedures, namely, expectation maximization and variational Bayes. The robustness of the extended Kalman filter method, whether used independently or in conjunction with the expectation maximization or variational Bayesian approaches, is evaluated through a numerical study. The numerical study yields practical strategies for tuning the algorithm hyperparameters so as to obtain more rapid, accurate, and unbiased estimates of the fault intensity and the remaining time-to-critical. The performance and efficiency of these strategies are then experimentally validated by determining the leakage area and time-to-critical in a lab-scale pressure vessel.
THE ELABORATION OF A HIGHLY EFFECTIVE MICROBIOLOGICAL FERTILISER BASED ON STRAINS OF NITROGEN-FIXING BACTERIA
Authors:   Lomonosov Institute of Fine Chemical Technologies, Moscow, Boshlyakov G.S. , Grishina E.V. , Paiberdin A.O. , Pak D.V. , Petrova A.M. , Rodionov E.M. , Yurina I.A. , Zolotareva M.S.
Published: February 2025

Mineral fertilizers lose their effectiveness. It improved by adding microbiological fertilizers. Six bacterial strains were isolated
and characterized, and their agronomic potential was studied. A dense nutrient medium was optimized. Two strains were found to enter
into antagonistic relationships with P. chlororaphis 449. Spectrofluorometry showed the accumulation of siderophores. Strains were
determined using spectrometry and Sanger sequencing methods.
ASSESSMENT OF THE TOXIC EFFECTS OF ORGANOCLAYS AND THEIR COMPLEXES WITH PB (II) ON AUTOTROPHIC SOIL MICROORGANISMS
Authors:   Tula State Lev Tolstoy Pedagogical University, Gertsen M.M. , Perelomov L.V.
Published: February 2025

The toxic effect of organoclays and their complexes with lead cations on the community of autochthonous soil bacteria in grey
forest soil was studied. It was found that, at 1 % concentration, organoclay based on alkyl polyglucosides (amphoteric surfactants) and
disodium cocamphodiacetates (nonionic surfactant), have minimal toxicity regardless of the method of introduction.