bluuebunny/crossref_metadata_2025 huggingface dataset:
An AI Dietitian for Type 2 Diabetes Mellitus Management Based on Large Language and Image Recognition Models: Preclinical Concept Validation Study (Preprint)
Authors: Sun Haonan , Zhang Kai , Lan Wei , Gu Qiufeng , Jiang Guangxiang , Yang Xue , Qin Wanli , Han Dongran
Published: August 2023

BACKGROUND

Nutritional management for patients with diabetes in China is a significant challenge due to the low supply of registered clinical dietitians. To address this, an artificial intelligence (AI)–based nutritionist program that uses advanced language and image recognition models was created. This program can identify ingredients from images of a patient’s meal and offer nutritional guidance and dietary recommendations.

OBJECTIVE

The primary objective of this study is to evaluate the competence of the models that support this program.

METHODS

The potential of an AI nutritionist program for patients with type 2 diabetes mellitus (T2DM) was evaluated through a multistep process. First, a survey was conducted among patients with T2DM and endocrinologists to identify knowledge gaps in dietary practices. ChatGPT and GPT 4.0 were then tested through the Chinese Registered Dietitian Examination to assess their proficiency in providing evidence-based dietary advice. ChatGPT’s responses to common questions about medical nutrition therapy were compared with expert responses by professional dietitians to evaluate its proficiency. The model’s food recommendations were scrutinized for consistency with expert advice. A deep learning–based image recognition model was developed for food identification at the ingredient level, and its performance was compared with existing models. Finally, a user-friendly app was developed, integrating the capabilities of language and image recognition models to potentially improve care for patients with T2DM.

RESULTS

Most patients (182/206, 88.4%) demanded more immediate and comprehensive nutritional management and education. Both ChatGPT and GPT 4.0 passed the Chinese Registered Dietitian examination. ChatGPT’s food recommendations were mainly in line with best practices, except for certain foods like root vegetables and dry beans. Professional dietitians’ reviews of ChatGPT’s responses to common questions were largely positive, with 162 out of 168 providing favorable reviews. The multilabel image recognition model evaluation showed that the Dino V2 model achieved an average F1 score of 0.825, indicating high accuracy in recognizing ingredients.

CONCLUSIONS

The model evaluations were promising. The AI-based nutritionist program is now ready for a supervised pilot study.
ChatGPT may be an effective tool to increase access to language-concordant care for patients with non-English language preference (Preprint)
Authors: Dzuali Fiatsogbe , Seiger Kira , Novoa Roberto , Aleshin Maria , Teng Joyce , Lester Jenna , Daneshjou Roxana
Published: August 2023

UNSTRUCTURED

The artificial intelligence (AI) model, ChatGPT, was evaluated for its ability to translate patient education materials from English into Spanish, Mandarin, and Russian. The translated materials were reviewed by board-certified dermatologists fluent in the target languages. Misinformation was prevalent in the Mandarin translations, and all languages showed instances of grammatical and spelling errors. However, the majority of reviewers agreed that the Russian and Spanish translations could be provided to a patient. The study highlights the potential of AI to facilitate patient education for patients with non-English language preferences and also highlights the need for review to ensure the accuracy of translated materials.
The Fine Print: Exploration of Data Privacy Policies and the Threats Posed to Reproductive Health App Users (Preprint)
Authors: Zadushlivy Nina , Biviji Rizwana , Williams Karmen S.
Published: August 2023

BACKGROUND

Although many mobile applications require the input of identifiable information, certain users are at a higher risk when the data collected is not properly stored and secured. With the changes in government, such as the overruling of Roe v. Wade just over a year ago, users in the US, specifically those of reproductive health apps, are susceptible to these risks. Limited studies have analyzed data privacy policies of reproductive health apps and considered the safety concerns associated with lack of user protection.

OBJECTIVE

This study aims to analyze the most commonly utilized reproductive health apps and their individual data policies, in addition to the differences between laws governing data in the United States and in the European Union.

METHODS

Four popular reproductive health apps, selected based on their popularity and country of origin, were downloaded for comparison of respective data use, storage, and sharing policies, demographic ratings, and data security measures. The THESIS Evaluation Tool was used to rate the privacy and security of the selected apps. A content analysis of existing data privacy laws was also conducted to determine efficiency of app use and data protection.

RESULTS

Findings indicated that while the four reproductive health apps have privacy policies intended to provide users with assurance of data security, there are loopholes that endanger their users. These can include collection of identifiable information with and without proper anonymization or encryption, the sharing of this data with analytical and marketing third parties, and the created accessibility of user information upon request from government agencies, whether through the app itself or third-party platforms. Three out of the four apps collect identifiable information, with one limiting data collection the most. Despite the pretense of not sharing data, all four apps do provide data to third parties, whose own privacy policies vary and may not align with data protection protocols.

CONCLUSIONS

Personal data collected by the app, even unidentifiable, may be linked to specific users and shared with third parties. While there are pending laws pertaining to data privacy, responsibilities fall onto the individual apps themselves to ensure their user data safety.
Designing PEM Electrolysis-Based Hydrogen Reactors In The Area of Baron Beach Of Yogyakarta, Indonesia
Authors: Nugroho Danu , Arief Budiman  , Eko Agus Suyono  , Wahyu Wilopo
Published: August 2023

This study aimed to design a PEM electrolysis-based hydrogen reactor and the potential for hydrogen production at Baron Beach, Gunung Kidul, Yogyakarta. Based on the calculation done at the initial process, the electrical energy potentially generated from renewable energy, such as wind, waves, and solar, reached 10.7 MW. This study also investigated the effect of reactor operating temperature on reactor efficiency and hydrogen production. A numerical thermodynamic approach was applied in the design process. The model, validated by laboratory experiments by other institutions, was in good agreement with previous research with an error value of 13%. The temperature range was dynamically limited from 30 to 80°C. The optimum operating conditions occurred when the temperature was set at 80 °C with a reactor efficiency, a water consumption rate, and a hydrogen production capacity of 76.3%, 2.817 kg/hour, and 250.42 kg/hour, respectively. The raw material, namely seawater, was processed using the reverse osmosis method. Ten reactors (with 13 cells per reactor) were installed in parallel.
ESL/EFL Teachers’ Role in Moral and Political Education in China and Its Implications for Pre-Service Teacher Education
Authors: Liu Hui
Published: August 2023

ESL/EFL teaching exhibits a strong compatibility with moral and political education, and its classroom is a natural place for instruction. Teachers assume pivotal roles as leaders, designers, and practitioners, wielding considerable influence over the quality of foreign language teaching through their capacity to impart moral values and cultivate ethical awareness. It is imperative to incorporate moral values into teacher education to equip teachers with the requisite skills to foster moral development in their students. However, the pre-service education in China has failed to address the issue, resulting in a lack of pertinent training. As a result, in-service teachers often encounter challenges when attempting to integrate moral and political education into their pedagogical practices, including a deficiency in relevant knowledge, inadequate skill sets, and inappropriate teaching methods. Consequently, a crucial necessity exists for comprehensive revisions to pre-service education programs, particularly to curriculum and course design, to meet the specific needs of ESL/EFL teachers.
REVOLUTIONIZING ANTIMICROBIAL DRUG DISCOVERY: COMPUTATIONAL DESIGN AND ADMET STUDIES OF EMERGING POTENT ANTI-MICROBIAL AGENTS
Authors: CHAKRABARTI MADHURITA
Published: August 2023

Objective: This study focuses on designing potential antimicrobial agents, evaluating their binding affinity against target proteins, and assessing their Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) properties using computational methods.
Methods: This study employed six target proteins from the Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) and utilized Biovia Discovery Studio 2021 for their preparation. Marvin Sketch is used to draw the ten potential candidates and subjected to molecular docking using Python Prescription (PyRx) software. The Biovia Discovery Studio 2021 was used to visualize the docking outcomes, and ADMET properties were determined using Swiss ADME software.
Results: Docking experiments conducted on ten derivatives against six protein targets, specifically Sortase-A, Clumping factor A, Undecaprenyl diphosphate synthase, Dehydrosqualene synthase, Tyrosyl tRNA synthetase, and Dihydrofolate reductase. Out of the ten derivatives, compounds 1, 2, 3, 5, and 7 demonstrated a significant binding affinity for one or two target proteins. Notably, compound 8 exhibited exceptional docking scores against five of the six protein targets, establishing itself as the most potent ligand among the compounds tested. These results highlight the paramount significance of compound 8 for subsequent investigation. Furthermore, comprehensive documentation of the physicochemical properties of the potent derivatives was carried out.
Conclusion: The findings indicate that the examined compounds have the potential to effectively inhibit various microbial protein targets. In silico ADMET studies suggest that these compounds possess desirable drug-like properties. Therefore, these compounds hold promise as lead molecules for further research, potentially leading to the development of novel antimicrobial drugs.
Geocronología U-Pb y geoquímica del vulcanismo de arco del Paleoceno de la Formación Tetelcingo en el área de Chilpancingo-Tixtla, Guerrero (sur de México)
Authors: Sarmiento-Villagrana Alicia , Ortíz-Degante Sandra Magaly , Talavera-Mendoza Oscar , Ocampo-Díaz Yam Zul Ernesto
Published: August 2023

Los depósitos continentales del Paleógeno (Grupo Balsas) del sur de México han sido poco estudiados y se desconoce en gran medida su origen, edad, naturaleza y ambiente tectónico de formación; elementos cruciales para comprender la relación del sur de México con Centroamérica y América del Sur. En este sentido, se realizó un estudio en el que se reportan por primera vez datos de estratigrafía, geoquímica y geocronología U-Pb de las rocas volcánicas de la Formación Tetelcingo del área de Chilpancingo-Tixtla, Guerrero. La Formación Tetelcingo es una secuencia volcano-sedimentaria cuyas rocas están depositadas discordantemente sobre rocas cretácicas (formaciones Morelos y Mezcala). La geoquímica de las rocas volcánicas indica una variación composicional de andesita a dacita. Todas las muestras presentan enriquecimiento en elementos litófilos de radio iónico grande (LILE) y en tierras raras ligeras (LREE), con respecto a los elementos de alto potencial iónico (HFSE) y tierras raras pesadas (HREE). Además, exhiben anomalías negativas en Nb, Ta, P y Ti; positivas en Ba, Sr y K; y escasas a inexistentes anomalías en Eu (0.69-1.04), así como concentraciones altas de Sr y bajas en Yb, Y, Ni y Cr. El emplazamiento de las rocas volcánicas estudiadas ocurrió durante dos ciclos de vulcanismo sucesivos; el primer ciclo inició entre 65.21 ± 0.97 Ma (zircón) y 66.7 ± 2.9 Ma (esfena), mientras que el segundo entre 65.27 ± 1.9 Ma (zircón) y 64.9 ± 4.4 Ma (esfena) U-Pb. Las rocas volcánicas de la Formación Tetelcingo muestran características geoquímicas similares a las adakitas formadas en un ambiente de arco continental. El emplazamiento de las rocas volcánicas ocurrió en el límite Cretácico-Paleógeno, en un contexto geodinámico con subdución activa y subsecuente transtensión y exhumación relacionada al desprendimiento y migración del bloque Chortís hacia el sureste.
El complejo volcánico de Ahualulco: geoquímica y evolución temporal del vulcanismo félsico del Oligoceno, en el oriente de la Mesa Central, San Luis Potosí, México
Authors: Latorre-Correa Carolina Isabel , Dávila-Harris Pablo , Aguillón-Robles Alfredo , Tristán-González Margarito
Published: August 2023

El complejo volcánico de Ahualulco (CVA), en la región meridional de la Mesa Central de México, consta de un conjunto de rocas volcánicas cenozoicas que incluye andesitas emplazadas en el Eoceno medio, seguidas de lavas dacíticas y riolíticas, al igual que secuencias piroclásticas félsicas emitidas durante el Oligoceno, algunas de las cuales contienen granate. En este trabajo se ha encontrado que, al menos, un segundo evento andesítico (andesita Petronilas) ocurrió en ese lapso, y que estuvo ligado a la génesis de la ignimbrita Cortes (de composición riolítica), conformando así un volcanismo bimodal “atípico” evidenciado por las relaciones de campo, mineralogía, correlación de los elementos incompatibles Th y Nb y los patrones de las tierras raras. Adicionalmente, se obtuvieron nuevas edades de cristalización de zircón por el método U-Pb para la Riodacita Zapatero (31.7 Ma), la Riolita Los Cuervos (30.8 Ma), la riolita granatífera El Arenal (31.4 Ma) y el pórfido riolítico El Negro (31.1 Ma). Posiblemente, el emplazamiento de la suite bimodal, así como el de las rocas encontradas en el norte, es de tipo fisural asociado a las fallas NW-SE originadas en el régimen extensivo que ocurrió entre el Oligoceno y el Mioceno. Sin embargo, en el centro del CVA se requiere de una historia eruptiva similar a la de las calderas de colapso para explicar ciertos hallazgos litológicos y estratigráficos, como la presencia de grandes brechas, con abundantes clastos graníticos y de rocas sedimentarias basales del Cretácico, en las tobas Palos Colorados y Hienera.
Las anomalías: ¿qué son?, ¿dónde surgen?, ¿cómo detectarlas?
Authors: Hevia Montiel Nidiyare , Mota Pantoja Sergio Iván , Neme Castillo José Antonio
Published: August 2023

Una anomalía es una instancia que no se asemeja a la mayoría de las observaciones. Establecer los criterios de comparación, que nos permitan identificar a una instancia como posible anomalía es una tarea abierta en Inteligencia Artificial (IA). La baja frecuencia de estas dificulta tener datos para extraer atributos, que nos proporcionen una idea de qué hace diferente a una anomalía con respecto a las observaciones usuales o habituales. La idea general de los algoritmos de detección de anomalías pasa por escudriñar las observaciones usuales o habituales, para extraer algún criterio o métrica que sea compartida por ellas, y que posea la propiedad de no estar presente en observaciones anómalas. La práctica tradicional para detectarlas es asociarlas a ruido o error en las observaciones y descartarlas. Una perspectiva moderna dice que: una anomalía o discrepancia es un indicio, posiblemente temprano, de algún cambio importante en el objeto de estudio. En este trabajo, presentaremos definiciones operativas, relataremos en qué contextos surgen, y haremos un recorrido sobre algunos algoritmos para su detección.
El impacto del empoderamiento en la satisfacción laboral, el compromiso organizacional y el burnout en docentes de México
Authors: Treviño Reyes Rosalba , López Pérez Jesús Fabián
Published: August 2023

La presente investigación analiza la relación entre el Empderamiento Estructural y las Remuneraciones con la Satisfacción Laboral, el Compromiso Organizacional y el Burnout mediante el Empoderamiento Psicológico en docentes de educación media superior en México, así como sus contrastes y diferencias de impacto entre los grupos de segmentación. Se realizó el estudio con un diseño no experimental y transversal con alcance correlacional y causal. Se aplicó el instrumento de medición a una muestra de 167 docentes, cuyos datos fueron analizados bajo el método de ecuaciones estructurales. Los hallazgos avalan el impacto positivo del Empoderamiento Estructural en la Satisfacción Laboral, y de las Remuneraciones en el Compromiso Organizacional, mediante el Empoderamiento Psicológico; pero no avalan el impacto negativo en el Burnout, lo cual contrasta con la literatura revisada. Los docentes a quienes la organización les brinda apoyo, información, recursos y oportunidades para aprender y desarrollarse presentan mayores niveles de Satisfacción Laboral y Compromiso Organizacional, así como quienes son mejor remunerados se encuentran más comprometidos con su labor e institución. Entre las limitaciones destacan: los datos son recabados una vez en el tiempo y se orientó la muestra a aquellos docentes que estuvieran disponibles para responder las encuestas.
La diversidad de la estructura económica local y su relación con la demanda ocupacional y los índices de pobreza en las zonas metropolitanas de México
Authors: Segura Mojica Francisco Javier
Published: August 2023

Esta investigación explora la forma en que la diversidad de la estrucura económica en las zonas metropolitanas se relaciona con la demanda ocupacional y con los índices de pobreza moderada y extrema. Se analizaron datos de una muestra de 29 zonas metropolitanas de México. Al análisis se incorporaron las variables Índice de Diversidad de Simpson (IDS), Tasa de Informalidad, Variación del PIB Estatal y Años de Escolaridad como predictores de empleo y pobreza.   Como herramientas de análisis se utilizó estadística descriptiva e inferencial y se formularon modelos de regresión lineal y PLS. Como resultado relevante se encontró que existe una correlación significativa de signo positivo entre el IDS y el número de Asegurados Permanentes; así como correlaciones significativas de signo negativo entre el IDS y el porcentaje de población en situación de pobreza moderada y pobreza extrema.
Litiasis masiva de la vía biliar intra y extra hepática. Reporte de 2 casos
Authors: Sánchez Amaro Eddie Xhamanchi , Alcántar Villanueva Héctor , Martínez Ortíz Alfonso , Paulo Valdivieso Edgar
Published: August 2023

The joint and massive presence of gallstones from the bile duct, both intra and extra hepatic, is a rare entity within the western population. Two cases are presented below, which debuted with a clinical picture of pain in the right hypo¬chondrium and with a clinical picture of pain in the right hypochondrium and with clinical and laboratory data of bile duct obstruction, and that by means of a resonance cholan¬giography study, multiple endoluminal stones of the bile duct are evidenced. Overall, it also shows the treatment of one of the cases by ERCP with successful evacuation of the gallstones. Keywords: Lithiasis; bile duct; massive; resonance cholangio; endoscopic retrograde cholangiography (ERCP).
La función de las proteínas de choque térmico en las infecciones virales
Authors: Olvera-Sánchez Sofía , Martínez Federico
Published: August 2023

Heat- shock proteins (HSP) were first described as a cell response to heat stress. However, over time, it has become clear they have multiple functions inside and outside cells, and that they actively participate in different physiological and pathological processes. They perform functions related to their cellular location or physiological moment, which is why they have been called multi-use proteins or “moonlighting proteins”. Furthermore, HSP activity is associated with different structural conformations, from peptides derived from them or as dimers or multimers, to mention a few. This article describes these functions and their relationship with the immune system, and their relationship with viral infection, particularly with inflammatory processes. Keywords: HSP; viral infection; COVID-19; immune system; inflammation processes.
Tortional Effect in Vertically Mass Irregular RC Frame Structure under Response Spectrum Analysis
Authors: Sapate Vishal , Chincholkar Mahesh R.
Published: August 2023

Abstract: The structures having discontinuity like distribution of mass, stiffness and geometry of the structure are termed as Irregular structures. Irregular structures contribute a large portion of urban infrastructure. The past earthquakes have shown catastrophic effect on the buildings with irregularities. It was seen that the buildings with irregularities are more prone to earthquake then the regular building. In the present study a special case of vertical mass irregularity are discussed. Six different models including three basic cases of buildings models i.e. vertically regular structure, vertically irregular structure and vertically irregular structure with shear wall at different position are taken for analysis by Response spectrum. It has observed that, the torsion, base reaction, displacement and modal load participation ratio in structure. This study exhibits effect of mass variation aspect of RCC structure
Need of EI in Today’s World
Authors: Jagtap Pratiksha L. , Dhopeshwarkar Mukta
Published: August 2023

Abstract: Emotional intelligence and intelligence quotient are frequently contrasted. Many of us understand IQ as a person's performance on a set of tests intended to measure to gauge intellectual capacity. People with higher IQs have superior cognitive talents, which include the capacity to learn and comprehend, and they are more likely to succeed in school. The intelligence quotient measures a person's IQ, but the emotional intelligence (EI) quotient (EQ) measures a notion that comprises the capacity, skill, or self-perceived ability to identify, appraise, and manage one's own, other people, and group members' emotions. The EQ notion contends that conventional intelligence, or IQ, is overly limited and that emotional intelligence encompasses a larger range of skills. enable our level of achievement. Emotional intelligence is crucial in the workplace. While cognitive abilities are seen to aid in landing a job, emotional intelligence is thought to aid in landing promotions. People who have higher emotional intelligence requirements than individuals at lower levels of the corporate hierarchy. Emotional intelligence is regarded as being twice as significant in the job as analytical and technical skills. The purpose of this study is to discuss the idea of emotional intelligence as a crucial area for professional development and to emphasise its significance in the workplace.
Peranan Sultan Muhammad Ali Muazzammsyah dalam Mendirikan Kota Pekanbaru (1765-1779)
Authors: Zamzarina Dina , Bunari Bunari , Fikri Asyrul
Published: August 2023

The name Pekanbaru was formerly known as Senapelan. The development of Senapelan is very close to the Kingdom of Siak Sri Indrapura. The Siak Kingdom is a religious kingdom which is a continuation of the Johor Kingdom which was split into two regions, one of which is the Siak Kingdom which was founded by Sultan Jalil Rachmad Syah who is known as Raja Kecik. The existence of Pekanbaru City (the capital of Riau Province) cannot be separated from the role of Sultan Muhammad Ali Abdul Jalil Muazzamsyah who holds the title of Marhum Pekan in establishing this city. From a simple village (Kebatinan Senapelan) to become the capital of the Kingdom of Siak and is now a Metropolitan city. During Sultan Muhammad Ali leading the Kingdom of Siak, he built Negeri Senapelan and gave the city a new name Pekanbaru. To find out the background of Sultan Muhammad Ali Muazzamsyah's life and to know the role of Sultan Muhammad Ali Muazzamsyah in establishing Pekanbaru, making Senapelan a trading center. This research is research that seeks to reconstruct the Role of Sultan Muhammad Ali Muazzamsyah in Establishing the City of Pekanbaru (1765-1779) considering that events occurred in the past, the method used is the historical method with steps namely Heuristics, Verification, Interpretation and historiography. The result of this research is to reconstruct the role of Sultan Muhammad Ali Muazzamsyah in order to make Senapelan a trading center.
Asetilsalisilik Asit ve Salisilik Asitin Paklitaksel ile Eş Uygulamasının Prostat Kanseri Hücreleri Üzerindeki Olası Sinerjistik Etkilerinin Otofaji, ER stresi ve Apoptotik Hücre Ölümü ile İlişkisinin Araştırılması
Authors: ERZURUMLU Yalçın , ÇATAKLI Deniz , DOĞAN Hatice Kübra
Published: August 2023

Prostat kanseri, dünya genelinde erkeklerde en sık görülen ikinci kanser türüdür ve kansere bağlı ölüm nedenleri arasında beşinci sırada yer almaktadır. Kemoterapötikler ve anti-androjenler prostat kanseri tedavisinde sıklıkla kullanılan yaklaşımlar olmasına karşın kazanılan ilaç direnci ve gelişen kastrasyona direnç mekanizmaları nedeniyle kullanımları sınırlanmaktadır. Bu nedenle mevcut tedavilere ait yan etkilerin giderilmesi ve hali hazırda kullanılan ajanların terapötik etkinliklerinin geliştirilebilmesi için yeni yaklaşımlara olan ihtiyaç devam etmektedir. Bu çalışma kapsamında, asetilsalisilik asit (ASA) ve salisilik asit (SA)’in tek başına veya kemoterapiye dirençli çeşitli kanser türlerinin tedavisinde sıklıkla kullanılan bir anti-mitotik ajan olan Paklitaksel ile kombine uygulamalarının prostat kanseri hücrelerinde katlanmamış protein yanıtı (UPR) sinyalinin PERK kolu, otofaji ve apoptotik hücre ölümü aracılı olası etki mekanizmaları incelendi. Bulgularımız, Paklitaksel’in ASA ve SA ile kombinasyonunun otofaji mekanizmasını uyardığını ve UPR’nin PERK kolu aktivasyonu aracılı CHOP uyarımına ve apoptotik proteinler olan kaspaz-3 ve PARP-1 kesimine neden olarak prostat kanseri hücrelerinde güçlü anti-kanser etkiler sergilediğini göstermiştir. Bu sonuçlar, prostat kanseri tedavisinde ASA ve SA’nın Paklitaksel ile kombinasyonunun Paklitaksel’in anti-kanser etkinliğini geliştirerek etkili bir tedavi yaklaşımı sunabileceğini düşündürmektedir.
Performance Analysis of Three Phase Induction Motor With Variable Frequency Drives Using Pulse Generator Pwm and Svpwm
Authors: Baringbing Ari Dwiki , Husodo Budi Yanto
Published: August 2023

Three-phase induction motor is an alternating current motor that is most widely used in industry or offices. In principle, the induction motor is operated at a constant speed, if the induction motor is given a load that is not balanced with its constant speed, the speed of the induction motor will change. For this reason, one of the common methods used to adjust the rotational speed of an induction motor as desired is to use a Variable Frequency Drive (VFD). The VFD can be controlled by pulse generator PWM (pulse width modulation) and SVPWM (space-vector pulse width modulation) which are part of the value of the frequency and modulation index. In this final project, what is investigated and compared for more optimal results is the PWM and SVPWM output values with the variables of Rotor Speed, Slip, Fslip, Stator Current, and THD (Total Harmonic Distortion). In this thesis, a comparison of simulation with MATLAB between PWM and SVPWM is carried out using design and experimental methods. The final result obtained is for Rotor Speed, SVPWM control is more optimal with an average percentage of 2.2%. For more optimal SVPWM control slip reaches 1.53%. for Fslip control SVPWM is more optimal reaching 0.76%, SVPWM control produces a smaller current consumption at a frequency of 50 - 40 Hz. for THD Current, PWM control is more optimal with a percentage of 1.07%
Monitoring Sistem Pembangkit Listrik Tenaga Angin Berbasis Internet of Things
Authors: Wicaksono Dwi Haryo , Djuniadi Djuniadi , Apriaskar Esa
Published: August 2023

Terjadinya perubahan iklim yang ekstrem di Indonesia saat ini berdampak pada kenaikan suhu udara secara mendadak, hal ini dapat disebabkan karena tingkat polusi udara yang tinggi. Tingkat polusi udara yang tinggi disebabkan oleh penggunaan energi fosil secara terus menerus sebagai sumber energi utama, mulai dari pembangkit listrik bertenaga fosil hingga banyaknya kendaraan konvensional yang masih digunakan. Pembangkit listrik tenaga angin (PLTB) mampu menjadi solusi permasalahan penggunaan energi fosil. Angin dapat memutar generator turbin untuk menghasilkan energi listrik. Kecepatan angin yang melewati turbin sangat berdampak terhadap besarnya energi yang dihasilkan.  Kecepatan angin yang tidak stabil akan mempengaruhi proses pembacaan data output karena proses pengukuran output turbin angin masih menggunakan pengukuran manual (analog). Sehingga dalam proses pembacaan data output menjadi terganggu dan hasil yang didapat belum akurat. Tujuan dari penelitian ini adalah melakukan analisa monitoring terhadap energi yang dihasilkan dari suatu pembangkit listrik tenaga angin berbasis Internet of Things (IoT) menggunakan prototype yang telah dibuat. Prototype yang telah dibuat menggunakan Sensor INA 219 sebagai pengukur energi dari turbin dan NodeMCU sebagai pengontrol serta pengirim data yang dihasilkan sensor ke software Blynk. Dari hasil pengujian alat monitoring PLTB, diperoleh nilai tegangan yang dihasilkan turbin cukup stabil yaitu antara 0.86 V hingga 0.87 V dengan daya terbesar yang dihasilkan selama pengujian adalah 6370,93 mW. Perbedaan jarak turbin dengan kipas angin memberikan pengaruh yang signifikan terhadap besarnya nilai arus yang dihasilkan. Nilai arus yang dihasilkan selama pengujian yaitu 0,1 mA hingga 7,3 mA. Perubahan nilai tegangan tidak mempengaruhi kondisi LED.
PENGARUH BERBAGAI KONSENTRASI ROOTONE-F DAN KOMPOSISI MEDIA TANAM BERBEDA TERHADAP PERTUMBUHAN STEK JAMBU BIJI KRISTAL (Psidium guava L.)
Authors: Ulandari Sulistika , Lasmini Sri Anjar , Salingkat Chitra Anggriani
Published: August 2023

Penelitian ini bertujuan untuk mengetahui pengaruh konsentrasi rootone-F dan komposisi media tanam berbeda terhadap pertumbuhan stek jambu biji kristal. Waktu penelitian dimulai dari Juni sampai Agustus 2021. Penelitian ini menggunakan metode Rancangan Acak Kelompok (RAK) pola faktorial, faktor pertama yaitu konsentrasi rootone-F yang terdiri dari 4 taraf yaitu R1 (500 mg/l air), R2 (1000 mg/l air), R3 (1500 mg/l air) dan R4 (2000 mg/l air). Faktor kedua yaitu perlakuan media tanam yang terdiri dari 2 taraf yaitu M1 (Tanah + Pupuk Kandang Kambing 3:1) dan M2 (Tanah + Pupuk Kandang Kambing + Sekam Padi 3:1:1) sehingga diperoleh 8 kombinasi perlakuan, diulang sebanyak 3 kali sehingga terdapat 24 unit percobaan. Berdasarkan data yang telah diperoleh dalam penelitian ini maka dapat disimpulkan bahwa pemberian konsentrasi rootone-F 500 mg/l air memberikan pengaruh pertumbuhan tanaman lebih baik dibandingkan dengan konsentrasi lainnya dan penggunaan media tanam yang baik untuk digunakan yaitu campuran  tanah, pupuk kandang kambing dan sekam padi dengan perbandingan 3:1:1.
ANALISIS PEMASARAN CABAI RAWIT (Capsicum frutescens L.) DI DESA KASIMBAR BARAT KECAMATAN KASIMBAR
Authors: Daniel Tasya Kristin , Akrab Ali
Published: August 2023

Penelitian ini bertujuan untuk mengetahui saluran pemasaran, margin pemasaran, dan efisiensi pemasaran cabai rawit pada masing-masing saluran pemasaran di Desa Kasimbar Barat Kecamatan Kasimbar. Penentuan responden menggunakan metode sensus dengan mengambil seluruh populasi sejumlah 25 orang petani, 3 orang pedagang pengumpul dan pengecer, dan 2 orang konsumen. Analisis yang digunakan adalah Margin Pemasaran, Margin Total Pemasaran (MT), Bagian Harga yang diterima Petani (Sf) dan Efisiensi Pemasaran (EPs). Hasil penelitian menunjukan bahwa terdapat dua saluran pemasaran yang terjadi di Desa Kasimbar Barat. Margin pemasaran cabai rawit yang diperoleh di Desa Kasimbar Barat pada saluran pertama sebesar Rp 5.000/Kg, sedangkan pada saluran kedua sebesar Rp 7.500/Kg. Bagian harga yang diperoleh petani dari pemasaran cabai rawit pada saluran pertama yaitu sebesar 80%, sedangkan pada saluran kedua sebesar 70%. Efisiensi pemasaran cabai rawit di Desa Kasimbar Barat pada saluran pertama diperoleh hasil sebesar 1,34% dan saluran kedua diperoleh hasil sebesar 2,24%.
Analisis Kajian Hukum Tentang Otonomi Daerah Dan Penerapan Asas Otonomi Daerah
Authors: Imam Hafidz Ma'ruf , Mustain Nasoha R. Ahmad Muhamad , Nugroho Ilham Khafi , Fanani Rakhmad
Published: August 2023

This study evaluates the Regional Autonomy laws 32 of 2004 and 23 of 2014 in light of the Republic of Indonesia's 1945 Constitution. Where the power of autonomy to manage their own households is granted to the partition of these territories. This study is normative in character and is a legal normative study. The strategy is a normative juridical strategy. Primary data, namely the 1945 Constitution of the Republic of Indonesia and in particular Law Number 32 of 2004 and Law Number 23 of 2014 respecting Regional Autonomy, as well as secondary data were used, namely library data which includes documents official books, books on Regional Autonomy and Regional Economic Development, scientific journals and so on. And tertiary data taken from encyclopedias and dictionaries. The data obtained is then analyzed using Content Analysis on laws and regulations which are primary data. Based on the results of the research and analysis that has been carried out, it can be concluded that there are several ways to apply the principle of regional autonomy that can improve welfare and cooperation between regions nationally with unbalanced regional potential conditions such as geography and human resources. Regional autonomy as one of the instruments to realize prosperity in the form of ideal cooperation.
Condiciones de vida, violencia sexual y sintomatología psiquiátrica de mujeres afrocolombianas víctimas del conflicto armado colombiano: estudio de corte transversal en Cartagena, Colombia
Authors: Fernández Ruiz Mashiel , Lambis Anaya Lina , Durán Acero Karen Sofía , López Sampayo Nazly , Lozada Martínez Iván David , Suárez Causado Amileth
Published: August 2023

Objetivo: Evaluar el fenómeno de violencia sexual y condición de vida de mujeres afrocolombianas víctimas del conflicto armado, asentadas en la ciudad de Cartagena, Colombia.
Materiales y métodos: Estudio prospectivo de corte transversal, tipo encuesta poblacional, realizado entre septiembre de 2019 y marzo del 2020, en la ciudad de Cartagena, Colombia. Se evaluaron variables sociodemográficas, tipo de delitos sufridos en el conflicto armado y factores relacionados, además de antecedentes o presencia de sintomatología psiquiátrica asociada a los eventos traumáticos. A través de análisis descriptivo, se caracterizó las condiciones de vida actuales de las participantes y se exploraron asociaciones entre la condición de violencia sexual y sintomatología psiquiátrica, por medio de Odds Ratio (OR).
Resultados: Participaron 215 mujeres, con una mediana de edad de 40 años y desplazadas principalmente del departamento de Bolívar (55%). El 85% eran amas de casa y solo el 60% tiene vivienda propia, encontrándose más del 65% del total de las viviendas en zonas de riesgo por inundación. Por lo menos el 35% habían sufrido discriminación de género, racial o habían sido víctima de violencia sexual. Aproximadamente la mitad de la muestra declaró padecer insomnio, ansiedad y depresión. El 40% mencionó haber tenido pensamientos suicidas y solo 1 de cada 5 mujeres recibió apoyo psicológico. Haber sido secuestrada (OR 4,71; IC 95%, 1,05-21,07), perseguida (OR 3,33; IC 95%, 1,61-6,89) y abusada sexualmente (OR 3,09; IC 95%, 1,60-5,96), son hechos que se asociaron de forma sostenida y significativa con sintomatología psiquiátrica.
Conclusión: Las mujeres afrocolombianas víctimas del conflicto armado colombiano asentadas en Cartagena, presentan condiciones de vida inestables, no han recibido la ayuda adecuada de redes de apoyo, han sido discriminadas por su etnia, género y condición de víctima, y tienen una prevalencia elevada de sintomatología psiquiátrica asociada a los hechos traumáticos vividos.
Intoxicación por metahemoglobinizante, tipo propanil
Authors: Avellaneda Curcho Luis Carlos , Rodríguez Cabal Jenifer Tatiana , Romero Alarcón Daiyan Alexis , González Calderón Iván Camilo , García Agudelo Lorena
Published: August 2023

Las intoxicaciones por herbicidas propanil son frecuentes en las diferentes áreas agrícolas, sobre todo en los campos de cultivos de arroz. Se presenta el caso de un paciente agricultor, sin factores de riesgo, quien sufrió una intoxicación moderada por propanil. Pese a las limitaciones diagnósticas en cada centro hospitalario, la sospecha y los datos clínicos al ingreso pueden ser suficientes para la elaboración diagnóstica y su respectivo manejo.
Tratamiento del tabaquismo guiado por marcadores genéticos
Authors: Hincapié López Gloria , Isaza Mejía Carlos Alberto , Santafé Sánchez Robert , Beltrán Angarita Leonardo
Published: August 2023

Introducción: Entre las adicciones por drogas, el tabaquismo ocupa el primer lugar como causa de morbimortalidad y es factor de riesgo para seis de las ocho principales causas de muerte en el mundo. La nicotina es el principal componente adictivo del tabaco. En la terapia de reemplazo con nicotina (TRN), la vareniclina y el bupropion son los medicamentos aproba- dos para tratamiento del tabaquismo, pero los resultados de las clínicas de dejación del tabaquismo sugieren que aún se desconoce muchas variables influyentes en la respuesta al tratamiento.
Objetivo: Determinar la adherencia, la tolerabilidad y la efectividad de un programa de dejación de tabaquismo basado en nicotina o bupropion, en pacientes con dependencia al tabaco, seleccionados según los genotipos de las enzimas que metabolizan los dos fármacos.
Hallazgos clínicos: Se incluyeron en esta serie 21 fumadores, 67% hom- bres, con edad promedio de 46,2±11,7 años. Su tabaquismo comenzó a los 17,8±6 años y llevaban fumando 28±13 años. Al inicio del estudio fumaban 17±12 cigarrillos por día (CPD), habían hecho 3,7±2 intentos de dejar de fumar y el puntaje NDSS (escala breve de evaluación de dependencia de la nicotina, por sus siglas en inglés) fue de 22±5 (punto de corte para depen- dencia a nicotina: 11 o más puntos).
Tratamiento: Los pacientes tenían libre acceso telefónico al médico tra- tante y, cada semana, una consulta consistente en consejería y control del tratamiento farmacológico prescrito según los genotipos CYP2A6 (que co- difica la enzima que metaboliza la nicotina) y CYP2B6 (que codifica la enzima que metaboliza el bupropion). Se empleó nicotina en parches transdérmicos de 14 mg el primer mes y luego de 7 mg el segundo mes, complementados con chicles para manejo del síndrome de abstinencia y bupropion en forma de liberación regulada por 300 mg, 1-2 veces al día.
Resultados: Después de 8 semanas de tratamiento y 4 de observación, 15 sujetos (71,4%) respondieron en forma parcial/total. El consumo de CPD bajó de 17±12 al inicio del estudio, a 2,2±3,5 al final del estudio, que co- rresponde a una reducción de 195 cigarrillos/día. Siete de ocho pacientes tratados con bupropion (87,5%) y siete de trece tratados con nicotina (54%) tuvieron respuesta parcial/total. Solo un paciente formulado con nicotina suspendió el medicamento por intolerancia gastrointestinal (náusea y vó- mito). La tasa de recaídas, evaluada un mes después del tratamiento farma- cológico, fue de cero. Se encontró buena correlación genotipo-fenotipo en los individuos tratados con bupropion, pero no en los tratados con nicotina.
Relevancia clínica: La inclusión de marcadores farmacogenéticos para la elección de nicotina o bupropion en un programa de dejación de tabaquis- mo puede mejorar la adherencia, la tolerabilidad al fármaco y la efectividad del tratamiento.
Eventos emergentes en las prácticas educativas telepresenciales en tiempos de la pandemia COVID-19: Visión de docentes y estudiantes
Authors: a Cárdenas Ramírez Nancy Eugenia , Gómez Palacio Jhon Estiwar , Puentes Castro Miguel Ángel , Vélez Carvajal Julián David , Lucía Bedoya Olga , Cardona Arce Luz Angela
Published: August 2023

La presente investigación da cuenta de las experiencias y apreciaciones sobre las prácticas telepresenciales implementadas por docentes y estudiantes de instituciones educativas públicas y privadas, de los departamentos de Risaralda, Quindío, Córdoba, Cundinamarca, Valle del Cauca, Bolívar, Santander, Huila y Antioquia en Colombia, durante la pandemia del COVID-19 en el año 2020. El estudio se fundamentó en las categorías teóricas: esquemas observacionales desde los desarrollos teóricos de Von Foerster (1984) y Luhmann (1995), igualmente, prácticas educativas Zabala (1995), usabilidad Cobo (2005) y mediación TIC (Tecnologías de la Información y la Comunicación) desde la relación entre comunicación y cultura (Pardo y Cobo, 2020)., finalmente la categoría emergencia desde Sousa (2009) y Zemelman (1992).
Impact of Sociodemographic Factors, Stress, and Communication on Quality of Life in Survivors of Pediatric Cancer
Authors: Patterson Valdeoso , Olsavsky Anna , Garcia Dana , Sutherland-Foggio Malcolm , Vannatta Kathryn , Prussien Kemar , Bemis Heather , Compas Bruce , Gerhardt Cynthia
Published: August 2023

Background: While most research has largely focused on medical
risks associated with reduced quality of life (QOL) in survivors,
sociodemographic and family factors may also play a role. Thus, we
examined sociodemographic factors and family factors associated with
survivor QOL, including adolescent’s cancer-specific stress, mother’s
general stress, and mother–adolescent communication. Methods:
Mothers ( N=80) and survivors (ages 10-23, N=50) were
assessed 5 years following initial diagnosis. Mothers completed measures
regarding sociodemographic background adolescent’s cancer-specific
stress, mother’s general stress, mother–adolescent communication, and
adolescent QOL. Survivors also reported on their own QOL. Two
hierarchical multiple regressions examined predictors of: (a) mother’s
report of adolescent QOL and (b) survivor’s self-report of QOL.
Results: The final model predicting mother-reported adolescent
QOL was significant, F(5,74)=21.18, p<.001, and
explained 59% of the variance in QOL. Significant predictors included
adolescent stress ( β=-0.37, p<.001), mothers’
stress ( β=-0.42, p<.001), and communication (
β=0.19, p=.03). The final model predicting
survivor-reported QOL was also significant, F(5,44)=5.16,
p<.01 and explained 24% of the variance in QOL.
Significant predictors included adolescent stress ( β=-.37,
p=.01) and communication ( β=-.31, p=.04).
Sociodemographic factors were not a significant predictor of QOL in any
model. Conclusion: Family stress and communication offer
potential points of intervention to improve QOL of pediatric cancer
survivors from mother and survivor perspectives. While additional
research is needed, healthcare professionals should encourage stress
management and strong mother–child communication to enhance survivors’
long-term QOL. Such interventions may be helpful, irrespective of known
sociodemographic factors that often affect health.
An MRI Investigation of Trickle Flow
Authors: Fathiganjehlou Ali , Buist Kay , Peters E.A.J.F. (Frank) , Graaf Larry de , Kuipers J.A.M. (Hans)
Published: August 2023

Trickle bed reactors (TBR) are widely used in the chemical industries.
These reactors involve gas and liquid flow through a catalyst-packed
bed. For optimal TBR performance, it is crucial to achieve a uniform
distribution of gas and liquid among the catalyst particles. However, in
multi-tubular reactors with slender tubes, flow maldistribution near the
tube walls is a common issue. Therefore, a comprehensive understanding
of local phase and flow distribution is essential for designing and
operating reactors with slender tubes. This study employs Magnetic
Resonance Imaging (MRI) to characterize the three-dimensional
distribution of the two-phase trickle flow within a slender tube. Three
quantities are characterized: gas-liquid-solid distribution, particle
wetting efficiency, and the flow field. Structure and flow MRI images
are processed to calculate these quantities. Additionally, a novel
post-processing technique is introduced to determine the liquid
distribution over individual particle surfaces. This distribution is
determined at several axial and radial positions.
Influence of cholesterol levels on NSAID-associated cardiovascular risks after myocardial infarction: a population-based cohort study
Authors: Basem Mohab , Bonnesen Kasper , Pedersen Lars , Sørensen Henrik , Schmidt Morten
Published: August 2023

Purpose To examine whether low-density lipoprotein cholesterol
(LDL-C) levels influence the cardiovascular risk associated with
non-aspirin non-steroidal anti-inflammatory drug (NSAID) use after
myocardial infarction (MI). Methods Using Danish health
registries, we conducted a population-based cohort study of all adult
patients with first-time MI during 2010–2020 with an LDL-C value before
discharge. Based on the latest LDL-C value, we categorized patients into
a low and a high LDL-C group (<3.0 vs. ≥3.0 mmol/L). We
used time varying Cox regression to compute hazard ratios (HRs) with
95% confidence intervals of the association between NSAID use and a
major adverse cardiovascular event (MACE: recurrent MI, ischemic stroke,
and all-cause death). Results We followed 50,573 patients for a
median of 3.1 years. While exposed, 521 patients experienced a MACE: 312
in the low LDL-C group and 209 in the high LDL-C group. The HRs for MACE
comparing NSAID use with non-use were 1.21 (1.11–1.32) overall, 1.19
(1.06–1.33) in the low LDL-C group, and 1.23 (1.07–1.41) in the high
LDL-group. The HRs for recurrent MI and ischemic stroke were comparable
between the LDL-C subgroups. The HRs for all-cause death were 1.22
(1.07–1.39) in the low LDL-C group and 1.54 (1.30–1.83) in the high
LDL-C group. Changing the cut-off value for LDL-C to 1.8 and 1.4 mmol/L
showed consistent results. Conclusion In patients with MI,
LDL-C levels did not influence the increased risk of MACE associated
with NSAID use, but might influence the association between NSAID use
and all-cause death.