bluuebunny/crossref_metadata_2025 huggingface dataset:
New Trinitarian Ontologies? Trinitarian Theology, Theological Anthropology and Contemporary Critical Consciousness in Dialogue
Authors: Brown Teresa Grace
Published: June 2024

The recent translation into English of Klaus Hemmerle's Theses Towards a Trinitarian Ontology has led to a renewed interest in ontology and in the construction of new trinitarian ontologies. In his Theses, Hemmerle argues that a new trinitarian ontology discloses a new order of things: the analogy of Being becomes an analogy of the Trinity. A trinitarian ontology, therefore, turns on an axis of relationality and its impetus is reflexive and performative. In this article, I take up Hemmerle's argument that dialogue with theological anthropology is essential in the development of a trinitarian ontology. I engage the theological anthropologies of Kwok Pui‐Lan and Rita Nakashima Brock, whose work reflects a relational turn in theological anthropology, and bring these into dialogue with Hemmerle's insights. In doing so, I consider the implications of contemporary critical consciousness for thinking the human‐divine relationship and argue for a Christian trinitarian praxis which explicitly works to subvert narratives and structures that perpetuate the silencing of diverse discourses.
Investigating the mechanisms linking revenue recycling to increased political acceptability of carbon pricing
Authors: Muth Daniel
Published: June 2024

This paper analyzes the causal relationship between the carbon tax's revenue recycling measures and political acceptability. The Irish carbon tax reform of 2019 forms the basis of the study. The findings are based on deductive content analysis and semi‐structured, elite interviews with key politicians, climate policy advisors, and other influential figures involved in the policy‐making process. Analyzing the extensive Irish revenue recycling scheme, encompassing compensatory measures and various forms of climate spending, provides researchers with the chance to track distinctive causal mechanisms over the course of a politically intense period, leading up to general elections. The results show that relief measures were crucial to alleviate concerns about the negative distributional impact of the policy, which was fiercely attacked by some opposition parties. Additionally, climate spending increased political acceptance by offering low‐carbon alternatives to consumers, even though the policy was initially construed as punitive measure, especially in regions and sectors where switching to low‐carbon options, public transport, or less carbon intense heating, were challenging or even impossible. A unique finding of the study is that revenue recycling facilitates the emergence of cross‐party agreement among ideologically distant parties. Another crucial contribution of this study is the detailed comparison, from the perspective of political acceptability, of two alternative social compensation models, the fee and dividend model, and the integration of targeted social cushioning and climate spending (hypothecation).
Effect of soil drainage on Peruvian watergrass biochemical response and control by glyphosate
Authors: Silva Renan Souza , Camargo Edinalvo Rabaioli , Zuñiga Roque Maurício Palacios , Barbosa Julyana Vasconcelos , de Avila Luis Antonio
Published: June 2024

Peruvian watergrass (Luziola peruviana J.F. Gmel.) is a perennial weed often found in paddy fields in the southern region of Brazil. Its chemical control is performed mainly by herbicides such as glyphosate in burndown, whose efficacy depends on soil moisture. Under excess‐water soil conditions, glyphosate efficacy is reduced, probably due to reduced translocation and the involvement of photoassimilates partition. Furthermore, little is known about the stress tolerance of these plants subjected to water deficit. Based on that, we performed experiments to verify the effect of soil moisture on the biochemical parameters of Peruvian watergrass and glyphosate translocation to the stolon and roots. Total soluble sugars, sucrose, starch, and glyphosate concentrations in leaves, culms, roots, and glyphosate partitioning were quantified. The malondialdehyde content and the lipid peroxidation increased with the drainage. Under drainage conditions, superoxide production was higher in roots than leaves, while peroxide production was lower in roots than leaves. The electrolyte leakage increased with the drainage and glyphosate application. The total soluble sugar content varied in each organ with a significant increase in the culm 14 days after application in the draining treatment. Sucrose varied considerably and reached its maximum concentration at 21 days after herbicide application. The starch accumulation in the culm was 7 days after applying the highest glyphosate dose. The presence of glyphosate in the roots subjected to soil drainage indicates the movement of this herbicide. In conclusion, soil drainage profoundly impacts Peruvian watergrass physiology, increasing the photoassimilates and glyphosate translocation to the stolon and root. This explains why glyphosate efficacy is higher under drainage conditions.
Assessment of Urban Public Spaces within Shopping Malls: Youth Perspective in the City of Colombo
Authors: Nambuge G.S. , Peiris M.T.O.V. , Kalugalla K.G.P.
Published: June 2024

Cities are the engines of economic growth. With urbanization, the pressure on urban lands for production and consumption based land use is increasing. In this context, most cities endeavor to keep public spaces for people interaction especially in the form of open public space; and in this setting, urban dwellers tend to use alternative public spaces such as leisure parks, malls and arcades. This study seeks to identify the role of urban public spaces (UPS) in shopping malls in the city scale by comparing the use of five (5) internal and external factors - namely physical features, social activities, accessibility, land use mix, and also memories and experiences. The key user group considered was youth between the age group of 18 to 30 years and questionnaire surveys and semi-structured interviews were conducted in a span of 08 weeks. Analysis of the primary data was conducted through SPSS statistical software and narrative inquiry assessment was conducted to validate the survey outcomes. The findings revealed that internal features including physical and social factors were the most significant aspects for the youth to sense shopping malls as urban public spaces (UPS). Also the youth has been influenced by the surrounding leisure & recreation facilities to gain a sense of the shopping malls. Urban public spaces in shopping malls could be identified as a better alternative space for public parks and playgrounds from the youth perspective. This research revealed that size and activity mix within public spaces in shopping malls have played a significant role in the long term sustainability of functional efficiency.
Collaborative Governance in Land Acquisition and Aggregation Practices: The Impacts on Neighbourhood Functionalities in Tanzania
Authors: Alananga Samwel , Makupa Elitruder , Matotola Upendo
Published: June 2024

In urban development projects, the amount of land needs to be large enough to support not only the intended development but also the subsequent well-functioning of the neighbourhood through enhanced accessibility, service provision and liveability in general. Obtaining land for public goods and services at neighbourhood level may however be difficult especially in developing countries’ cities where the formal-informal continuum hampers the effective urban planning and development. This is attributed to the fact that a larger part of land in these cities is occupied and any public good or service provision initiative must be through either compulsory land acquisition or land aggregation approaches. In either approach there are pros and cons towards realising the well-functioning of the neighbourhood in terms accessibility, recreation, social services and other public amenities. Based on non-parametric tests of neighbourhood functionality differences across land access modalities, the survey data across wards in Dar es Salaam City, Tanzania it has been revealed that government action through compulsory acquisition of land may be justifiable in as much as the functioning of social and physical infrastructure is concerned but can limitedly be relied upon in making such facilities available in the first place. Voluntary contribution of land, open market purchase and even the voluntary contribution of cash are working better than compulsory acquisition of land for that purpose. Further evidence alludes to the fact that compulsory acquisition of land is not only detrimental to neighbourhood social networks but also can worsen neighbourhood level economic opportunities. As such alternatives to compulsory acquisition need be used in well-developed inner city neighbourhoods while some combination of compulsory or voluntary land and cash contributions are well suited in outskirt neighbourhoods.
Local connectedness of boundaries for relatively hyperbolic groups
Authors: Dasgupta Ashani , Hruska G. Christopher
Published: June 2024

Let be a relatively hyperbolic group pair that is relatively one ended. Then, the Bowditch boundary of is locally connected. Bowditch previously established this conclusion under the additional assumption that all peripheral subgroups are finitely presented, either one or two ended, and contain no infinite torsion subgroups. We remove these restrictions; we make no restriction on the cardinality of and no restriction on the peripheral subgroups .
Supplemental Material: Downward continued ocean bottom seismometer data show continued hydrothermal evolution of mature oceanic upper crust
Authors: Li Lianjun , al. et
Published: June 2024

Discussion of the downward continuation of OBS data (Figs. S1–S6) and subsequential tomographic inversion of VoiLA Line 2/3 (Figs. S7–S18 and Tables S1–S3).  
Blow-up of solutions for relaxed compressible Navier–Stokes equations
Authors: Hu Yuxi , Racke Reinhard
Published: June 2024

In this paper, we present a blow-up result for large data for relaxed compressible Navier–Stokes models avoiding the possibility of reaching the boundary of hyperbolicity. Thus, a previous result is improved and further examples are given illustrating possible effects of a relaxation and contrasting the classical compressible Navier–Stokes equations without relaxation where solutions for large data exist globally.
Analytical solutions to the compressible Euler equations with cylindrical symmetry and free boundary
Authors: Dong Jianwei , Wang Longquan , Chen Hao
Published: June 2024

In this paper, we study the analytical solutions to the compressible Euler equations with cylindrical symmetry and free boundary. We assume that the free boundary is moving in the radial direction with the radial velocity, which will affect the angular velocity but does not affect the axial velocity. By using some ansatzs, we reduce the original partial differential equations into an ordinary differential equation about the free boundary. We prove that the free boundary grows linearly in time by constructing some new physical functionals. Furthermore, the analytical solutions to the compressible Euler equations with time-dependent damping are also considered and the spreading rate of the free boundary is investigated according to the various sizes of the damping coefficients.
Vegetation Structure and Regeneration Status of Woody Species in Gerba Dima Moist Afromontane Forest of Southwestern Ethiopia: Implications for Conservation
Authors: Dibaba Abyot , Soromessa Teshome , Warkineh Bikila
Published: June 2024

This study assessed vegetation structure and regeneration status of woody species in Gerba Dima forest, southwestern Ethiopia. Ninety sample plots measuring 25 m × 25 m were laid through a stratified random sampling procedure. The studied forest was stratified into three forest strata based on its altitudinal variation. Stratum I was found at an altitudinal range of 1500−1800 m, while strata II and III were located at altitudinal ranges of 1801−2000 m and 2001−2300 m, respectively. All woody plant species with a diameter at breast height (dbh) equal to or larger than 2.5 cm and a height of at least 1.5 m were recorded. Analysis of the structure of the vegetation was conducted using frequency distribution of dbh, height, and importance value (IV). The regeneration pattern of the study species was assessed by employing the total count of seedlings and saplings. The density of woody species in the study area was 1829 individuals ha−1. Basal area of the Gerba Dima forest was 65.05 m2ha−1. Total densities of seedlings, saplings, and trees/shrubs were 4558 ha−1, 2149 ha−1, and 1515 ha−1, respectively. Structural analysis and assessment of the regeneration status of woody species in the Gerba Dima forest showed that the overall ecological condition of the forest was healthy as indicated by inverse J‐curve dbh distribution, which showed a large number of individuals in lower dbh classes. Furthermore, a large number of seedlings and saplings were recorded for most species, in addition to the presence of a sufficient number of matured trees. However, some species exhibited abnormal population structure and abnormal patterns of regeneration characterized by fewer or no individuals in lower dbh, as well as in seedling and sapling stages. It was thus concluded that species with abnormal population structure and regeneration status (e.g., Sapium ellipticum and Trichilia dregeana) require urgent conservation attention.
Comprehensive Immunohistochemical Analysis of Epithelial–Mesenchymal Transition Biomarkers in the Invasive Micropapillary Cancer of the Breast
Authors: Oz Ozden , Tasli Funda Alkan , Yuzuguldu Resmiye Irmak , Zengel Baha , Cavdar Demet Kocatepe , Durak Merih Guray , Durusoy Raika
Published: June 2024

Background: Invasive micropapillary carcinoma (IMPC) of the breast is commonly associated with a poor prognosis due to its high incidence of lymphovascular invasion and lymph node metastasis (LNM). Our study is aimed at investigating the prognostic significance of the expressions of E‐cadherin (E‐cad), N‐cadherin (N‐cad), CD44s, and β‐catenin (β‐cat). In addition, it is aimed at deciphering the consistency of these markers between the IMPC, the invasive breast carcinoma, no‐special type (IBC‐NST), and LNM components in the same IMPC cases.

Methods: Sixty‐two IMPC cases with LNM from 1996 to 2018 were analyzed. Immunohistochemical staining was performed separately on the three regions for each patient. Statistical analyses included Kaplan‐Meier, Cox regression, and McNemar’s statistical tests.

Results: Loss of CD44 expression in IMPC, IBC‐NST, and LNM areas was associated with poor prognosis in overall survival (OS) (p = 0.010, p < 0.0005, p = 0.025). Loss of CD44 expression in the IBC‐NST, gain of N‐cad expression in the IMPC, and loss of β‐cat expression in the LNM areas were indicators of poor prognosis in disease‐free survival (DFS) (p = 0.005, p = 0.041, p = 0.009).

Conclusion: Our evaluation of this rare subtype, focusing on the expression of key epithelial–mesenchymal transition (EMT) molecules, revealed that it shares characteristics with the IBC‐NST component within mixed tumors. Notably, contrary to expectations, a reduction in CD44 expression was found to adversely affect both OS and DFS. By conducting staining procedures simultaneously across three regions within the same patient, a novel approach has provided valuable insights into the mechanisms of EMT.
Functional and Nonfunctional Requirements of Virtual Clinic Mobile Applications: A Systematic Review
Authors: Parsaei Zahra , Jangi Majid , Tahmasebian Shahram , Ehteshami Asghar
Published: June 2024

Introduction: The Virtual Clinic Mobile Application (VCMA) is a valuable tool for managing and remotely monitoring patients with various medical conditions. It can alleviate the strain on outpatient services and offer follow‐up options for patients who do not require a physical examination. A thorough understanding of recent literature can assist in identifying suitable functionalities for new development and future improvement of current applications (apps). This review study is aimed at identifying functional and nonfunctional requirements for VCMA.

Methods: This study conducted a systematic search using databases such as PubMed, Scopus, ISI Web of Science, Science Direct, ProQuest, and IEEE to gather requirements of VCMA articles published in English from the inception of the databases up to April 2022. Out of a total of 1223 articles, 76 met the inclusion criteria. These articles were then analyzed using conventional content analysis to extract and categorize their requirements.

Results: Two main themes and 8 subthemes in terms of VCMA requirements were extracted as follows: (1) functional requirements with 3 subthemes (demographic data documentation, health record, general features of the user interface (UI)); (2) nonfunctional requirements with 5 subthemes (usability, accessibility, compatibility, efficiency, and security).

Conclusion: The findings highlight the importance of mHealth solutions for virtual care and the need for the development of apps based on the extracted functional and nonfunctional requirements for VCMA; however, controlled trials are necessary. It is recommended that transparent reporting of mHealth interventions be prioritized to enable effective interpretation of the extracted data.
Fibonacci Numbers Related to Some Subclasses of Bi‐Univalent Functions
Authors: Amourah Ala , Frasin Basem Aref , Salah Jamal , Al-Hawary Tariq
Published: June 2024

This research paper introduces the novel subclass of bi‐univalent functions that are connected to Fibonacci numbers. Our main contributions in this study involve establishing constraints on the absolute values of the second coefficient |a2| and the third coefficient |a3| for functions within this specific subclass. In addition, we provide solutions to Fekete–Szegö functional problems. Furthermore, our investigation reveals intriguing outcomes resulting from the specific parameter values used in our main findings.
Statistical Method from A Personalized Mass Spectrometry–Based Assay to Monitor M-Protein in Patients with Multiple Myeloma (EasyM)
Authors: Liyasova Mariya , McDonald Zac , Taylor Paul , Gorospe Kathleen , Xu Xin , Yao Chenyu , Liu Qixin , Yang Liqiang , Atenafu Eshetu G. , Piza Giovanni , Ma Bin , Reece Donna , Trudel Suzanne
Published: June 2024

The statistical method for the PFS analysis shown in Figure S2.
Figure S2 from A Personalized Mass Spectrometry–Based Assay to Monitor M-Protein in Patients with Multiple Myeloma (EasyM)
Authors: Liyasova Mariya , McDonald Zac , Taylor Paul , Gorospe Kathleen , Xu Xin , Yao Chenyu , Liu Qixin , Yang Liqiang , Atenafu Eshetu G. , Piza Giovanni , Ma Bin , Reece Donna , Trudel Suzanne
Published: June 2024

The progression free survival (PFS) according to M-protein status by EasyM.
Figure S1 from A Personalized Mass Spectrometry–Based Assay to Monitor M-Protein in Patients with Multiple Myeloma (EasyM)
Authors: Liyasova Mariya , McDonald Zac , Taylor Paul , Gorospe Kathleen , Xu Xin , Yao Chenyu , Liu Qixin , Yang Liqiang , Atenafu Eshetu G. , Piza Giovanni , Ma Bin , Reece Donna , Trudel Suzanne
Published: June 2024

The sequences of heavy and light chains of M-protein of patient 001-001 obtained through de novo protein sequencing by MS.
Data from A Personalized Mass Spectrometry–Based Assay to Monitor M-Protein in Patients with Multiple Myeloma (EasyM)
Authors: Liyasova Mariya , McDonald Zac , Taylor Paul , Gorospe Kathleen , Xu Xin , Yao Chenyu , Liu Qixin , Yang Liqiang , Atenafu Eshetu G. , Piza Giovanni , Ma Bin , Reece Donna , Trudel Suzanne
Published: June 2024

AbstractPurpose:
M-protein is a well-established biomarker used for multiple myeloma monitoring. Current improvements in multiple myeloma treatment created the need to monitor minimal residual disease (MRD) with high sensitivity. Measuring residual levels of M-protein in serum by MS was established as a sensitive assay for disease monitoring. In this study we evaluated the performance of EasyM—a noninvasive, sensitive, MS-based assay for M-protein monitoring.
Experimental Design:
Twenty-six patients enrolled in MCRN-001 clinical trial of two high-dose alkylating agents as conditioning followed by lenalidomide maintenance were selected for the study. All selected patients achieved complete responses (CR) during treatment, whereas five experienced progressive disease on study. The M-protein of each patient was first sequenced from the diagnostic serum using our de novo protein sequencing platform. The patient-specific M-protein peptides were then measured by targeted MS assay to monitor the response to treatment.
Results:
The M-protein doubling over 6 months measured by EasyM could predict the relapse in 4 of 5 relapsed patients 2 to 11 months earlier than conventional testing. In 21 disease-free patients, the M-protein was still detectable by EasyM despite normal FLC and MRD negativity. Importantly, of 72 MRD negative samples with CR status, 62 were positive by EasyM. The best sensitivity achieved by EasyM, detecting 0.58 mg/L of M-protein, was 1,000- and 200-fold higher compared with serum protein electrophoresis and immunofixation electrophoresis, respectively.
Conclusions:
EasyM was demonstrated to be a noninvasive, sensitive assay with superior performance compared with other assays, making it ideal for multiple myeloma monitoring and relapse prediction.
Supplementary Figure 1 from FOXO1 Inhibition Generates Potent Nonactivated CAR T Cells against Solid Tumors
Authors: Marchais Maude , Simula Luca , Phayanouvong Mélanie , Mami-Chouaib Fathia , Bismuth Georges , Decroocq Justine , Bouscary Didier , Dutrieux Jacques , Mangeney Marianne
Published: June 2024

Schematic representation of lentiviral constructs.
Movie Sup 1.TAS cells have greater migratory capacity than untreated T cells in viable Capan-2 tumors explant. from FOXO1 Inhibition Generates Potent Nonactivated CAR T Cells against Solid Tumors
Authors: Marchais Maude , Simula Luca , Phayanouvong Mélanie , Mami-Chouaib Fathia , Bismuth Georges , Decroocq Justine , Bouscary Didier , Dutrieux Jacques , Mangeney Marianne
Published: June 2024

Time-lapsed video of untreated T cells (green) and TAS cells (red) in slices stained with anti-Epcam (blue) for Capan-2 tumor cells and anti-gp38 (white) for stroma.
Supplementary Table S2 from Hemangiosarcoma Cells Promote Conserved Host-derived Hematopoietic Expansion
Authors: Kim Jong Hyuk , Schulte Ashley J. , Sarver Aaron L. , Lee Donghee , Angelos Mathew G. , Frantz Aric M. , Forster Colleen L. , O'Brien Timothy D. , Cornax Ingrid , O'Sullivan M. Gerard , Cheng Nuojin , Lewellen Mitzi , Oseth LeAnn , Kumar Sunil , Bullman Susan , Pedamallu Chandra Sekhar , Goyal Sagar M. , Meyerson Matthew , Lund Troy C. , Breen Matthew , Lindblad-Toh Kerstin , Dickerson Erin B. , Kaufman Dan S. , Modiano Jaime F.
Published: June 2024

Supplementary Table S2
Supplementary Figure S6 from Hemangiosarcoma Cells Promote Conserved Host-derived Hematopoietic Expansion
Authors: Kim Jong Hyuk , Schulte Ashley J. , Sarver Aaron L. , Lee Donghee , Angelos Mathew G. , Frantz Aric M. , Forster Colleen L. , O'Brien Timothy D. , Cornax Ingrid , O'Sullivan M. Gerard , Cheng Nuojin , Lewellen Mitzi , Oseth LeAnn , Kumar Sunil , Bullman Susan , Pedamallu Chandra Sekhar , Goyal Sagar M. , Meyerson Matthew , Lund Troy C. , Breen Matthew , Lindblad-Toh Kerstin , Dickerson Erin B. , Kaufman Dan S. , Modiano Jaime F.
Published: June 2024

Supplementary Figure S6
FIGURE 2 from Hemangiosarcoma Cells Promote Conserved Host-derived Hematopoietic Expansion
Authors: Kim Jong Hyuk , Schulte Ashley J. , Sarver Aaron L. , Lee Donghee , Angelos Mathew G. , Frantz Aric M. , Forster Colleen L. , O'Brien Timothy D. , Cornax Ingrid , O'Sullivan M. Gerard , Cheng Nuojin , Lewellen Mitzi , Oseth LeAnn , Kumar Sunil , Bullman Susan , Pedamallu Chandra Sekhar , Goyal Sagar M. , Meyerson Matthew , Lund Troy C. , Breen Matthew , Lindblad-Toh Kerstin , Dickerson Erin B. , Kaufman Dan S. , Modiano Jaime F.
Published: June 2024

Hematopoietic expansion derived from adoptive transplantation of canine hemangiosarcoma in immunodeficient mice. A and B, Xenotransplantation of canine hemangiosarcoma cell lines created exuberant myeloid hyperplasia in mouse spleens. Representative photomicrographs show histopathology by H&E staining of spleens from NSG mice transplanted with hemangiosarcoma cell lines SB (A) and EFB (B). C, Immunoreactivity of anti-mouse Ki-67 (Tec-3) antibody shows strongly positive signal in proliferating cells in the spleen. D, Immunostaining of anti-human (and canine cross-reactive) Ki-67 (MiB-1) antibody shows lack of positive staining among proliferating cells. E, The proliferating cells are immunoreactive with anti-mouse Ter-119 antibody. F, SB cells expressing Luciferase are detected in mouse spleen (arrows). Images shown in C, D, E, and F are from IHC staining done in mice inoculated with SB cells modified to express GFP and firefly Luciferase. Horseradish peroxidase (for Ki-67 stains) and alkaline phosphatase (for Ter-119 and Luciferase) conjugates were used. Counterstain = hematoxylin. A–D: Bar = 200 µm; E–F: Bar = 50 µm.
FIGURE 1 from Hemangiosarcoma Cells Promote Conserved Host-derived Hematopoietic Expansion
Authors: Kim Jong Hyuk , Schulte Ashley J. , Sarver Aaron L. , Lee Donghee , Angelos Mathew G. , Frantz Aric M. , Forster Colleen L. , O'Brien Timothy D. , Cornax Ingrid , O'Sullivan M. Gerard , Cheng Nuojin , Lewellen Mitzi , Oseth LeAnn , Kumar Sunil , Bullman Susan , Pedamallu Chandra Sekhar , Goyal Sagar M. , Meyerson Matthew , Lund Troy C. , Breen Matthew , Lindblad-Toh Kerstin , Dickerson Erin B. , Kaufman Dan S. , Modiano Jaime F.
Published: June 2024

Establishment of xenografts derived from canine hemangiosarcoma in immunodeficient mice. A, Schematic illustration depicts process of tumor xenografts in BNX mice. B, DHSA-1426 tumor cell line was established from a canine patient diagnosed with hemangiosarcoma (A). Cells from DHSA-1426 passages 5 (p5) and 14 (p14) formed tumors histologically classified as hemangiosarcoma (B and C). Cells cultured from xenograft-derived tumors developed histologically identical tumors after serial transplantation (D). Both the primary tumor (E) and the xenograft tumor (F) were positive for CD31 IHC staining. A–D, Hematoxylin and eosin (H&E) stain. E and F, IHC with an anti-CD31 antibody (alkaline phosphatase conjugates; counterstain = hematoxylin). Bar = 200 µm. C, FISH images using canine-specific (CXCL8, red) and mouse-specific (X chromosome, green) probes in a canine hemangiosarcoma xenograft transplanted into receptive immunodeficient female mouse hosts. Red and green arrows point to representative xenograft canine tumor cells and mouse stromal cells, respectively, to aid in identification. D, Individual points on graph represent relative quantity of donor (dog) and host (mouse) cells in each tumor type. 10–12 fields of pictures at high magnification (400X) per slide were acquired. A total of approximately 1,000 cells in individual xenograft tumor was counted, and the percentages for each species-specific cells are presented. E, Dot plot shows microenvironment scores for 76 primary hemangiosarcoma tissues, estimated using RNA-seq data and xCell algorithm. The red dot indicates a DHSA-1426 tumor tissue used for xenograft.
Transfer learning: classifying balanced and imbalanced fungus images using inceptionV3
Authors: Supriyadi Muhamad Rodhi , Alfin Muhammad Reza , Karisma Aulia Haritsuddin , Maulana Bayu Rizky , Pinem Josua Geovani
Published: June 2024

Identifying the genus of fungi is known to facilitate the discovery of new medicinal compounds. Currently, the isolation and identification process is predominantly conducted in the laboratory using molecular samples. However, mastering this process requires specific skills, making it a challenging task. Apart from that, the rapid and highly accurate identification of fungus microbes remains a persistent challenge. Here, we employ a deep learning technique to classify fungus images for both balanced and imbalanced datasets. This research used transfer learning to classify fungus from the genera Aspergillus, Cladosporium, and Fusarium using InceptionV3 model. Two experiments were run using the balanced dataset and the imbalanced dataset, respectively. Thorough experiments were conducted and model effectiveness was evaluated with standard metrics such as accuracy, precision, recall, and F1 score. Using the trendline of deviation knew the optimum result of the epoch in each experimental model. The evaluation results show that both experiments have good accuracy, precision, recall, and F1 score. A range of epochs in the accuracy and loss trendline curve can be found through the experiment with the balanced, even though the imbalanced dataset experiment could not. However, the validation results are still quite accurate even close to the balanced dataset accuracy.
Development of learning videos for natural science subjects in junior high schools
Authors: Siswosuharjo Partono , Al-Bahra Al-Bahra , Sunarya Po Abas
Published: June 2024

The purpose of this study was to determine the development procedure and the feasibility of learning media for whiteboard animation in Natural Sciences subjects at SMP Padindi, Tangerang Regency. This study uses a research and development (RD) approach. The development model in this study is the analysis design development implementation evaluation (ADDIE) model. The feasibility test is carried out by means of individual testing (one to one) on 3 experts, namely material experts, learning experts, and media experts, as well as 3 students. In addition, a small group test was also carried out on 9 students. The results showed that: i) the material expert test was 87.5%, the learning expert was 85%, the media expert was 84.44%, 3 students were 88.84%, and the small group was 90%; and ii) this whiteboard animation learning media is suitable for use based on the results of media trials by experts and students.
Acoustic echo cancellation system based on Laguerre method and neural network
Authors: Nguyen Duy-Thao , Nguyen Thanh-Nghia
Published: June 2024

Acoustic echo cancellation (AEC) is a fundamental requirement of signal processing to increase the quality of teleconferences. In this paper, a system that combines the Laguerre method with neural networks is proposed for AEC. In particular, the signal is processed using the Laguerre method to effectively handle nonlinear transmission line system. The results after applying the Laguerre method are then fed into a neural network for training and acoustic echo cancellation. The proposed system is tested on both linear and nonlinear transmission lines. Simulation results show that combining the Laguerre method with neural networks is highly effective for AEC in both linear and nonlinear transmission lines system. The AEC results obtained by the proposed method achieves a significant improvement in nonlinear transmission lines and it is the basis for building a practical echo cancellation system.
Os Sertões e a Imaginação de Um Leitor Deste Final de Século
Authors: Goto Roberto Akira
Published: June 2024

O autor procura analisar Os Sertões como obra literária. De modo a caracterizar o seu enfoque trágico, a obra-prima de Euclides da Cunha é comparada à tragédia de Eurípedes, As Bacantes. O artigo é concebido como ensaio literário, recorrendo-se à imaginação para visualizar um possível filme baseado em Os Sertões.
"A Nossa Vendéia": Canudos, o Mito da Revolução Francesa e a Formação de Identidade Cultural no Brasil (1897-1902)
Authors: Ventura Roberto
Published: June 2024

São aqui analisados os artigos e reportagens sobre o conflito de Canudos, escritos por Euclides da Cunha em 1897, e seu livro de 1902, Os Sertões: Campanha de Canudos. Esses textos são abordados segundo três aspectos: a) a relação entre cultura e extracultura, b) a construção (problemática) de Identidade nacional, c) a ambivalência entre identificação etnológica e distanciamento etnocêntrico. É enfocada a articulação entre tais aspectos e a projeção do modelo da Revolução Francesa sobre a história nacional nos primórdios da República brasileira.
A Metodologia da Tradução e o Texto de Guimarães Rosa
Authors: Lanciani Giulia
Published: June 2024

Conferência realizada durante a Semana Archives, aborda, principalmente a questão da transposição e da mudança de código no trabalho do tradutor. Cabe a ele compreender o universo do autor e da obra a que se dedica. Exemplos na tradução de Primeiras Estórias para o italiano.
Reflexões Sobre a Atual Crise Brasileira - II
Authors: Mauro José Eduardo Marques
Published: June 2024

Dando continuidade ao ensino "Reflexões sobre a atual crise brasileira", o autor aborda os temas: desorganização do aparelho burocrático, desestímulo à iniciativa privada e comunicação social deformada. No primeiro, enfatiza os vícios de origem da administração pública e as novas formas de clientelismo surgidas nos anos 50 e 60 do nosso século; no segundo, a predisposição que a estrutura econômica mostra à intervenção do Estado, desde o Convênio de Taubate; e, no terceiro, refere-se à tendência mundial a uma informação de alcance planetário.
Primary Atriopathy in Mitral Valve Prolapse: Echocardiographic Evidence and Clinical Implications
Authors: Tastet Lionel , Lim Lisa J. , Bibby Dwight , Hu Gene , Cristin Luca , Rich Amy H. , Jhawar Rohit , Fang Qizhi , Arya Farzin , Delling Francesca N.
Published: June 2024

BACKGROUND:

Prominent multi-scallop systolic leaflet displacement toward the left atrium (atrialization) is typically observed in bileaflet mitral valve prolapse (MVP) with mitral annular disjunction. We hypothesized that mitral leaflet atrialization is associated with an underlying left atrial (LA) myopathy characterized by progressive structural and functional abnormalities, irrespective of mitral regurgitation (MR) severity.

METHODS:

We identified 334 consecutive patients with MVP, no prior atrial fibrillation, and comprehensive clinical and echocardiographic data. LA function was assessed by LA reservoir strain, LA function index, and LA emptying fraction. We also classified the stage of LA remodeling based on LA enlargement and LA reservoir strain (stage 1: no remodeling; stage 2: mild remodeling; stage 3: moderate remodeling; and stage 4: severe remodeling). The primary end point was the composite risk of sudden arrhythmic death, heart failure hospitalization, or the new onset of atrial fibrillation.

RESULTS:

Bileaflet MVP with no or mild MR had a lower LA reservoir strain (
P
=0.04) and LA function index (
P
<0.001) compared with other MVP subtypes. In multivariable linear regression adjusted for cardiovascular risk factors and MR ≥moderate, bileaflet MVP remained significantly associated with lower LA function parameters (all
P
<0.05). There was a significant increase in the risk of events as the LA reservoir strain and LA remodeling stage increased (
P
<0.001). In multivariable analysis, stage 4 of LA remodeling remained significantly associated with a higher risk of events compared with stage 1 (hazard ratio, 6.09 [95% CI, 1.69–21.9];
P
=0.006).

CONCLUSIONS:

In a large MVP registry, bileaflet involvement is associated with reduced LA function regardless of MR severity, suggesting a primary atriopathy in this MVP subtype. Abnormal LA function, particularly when assessed through a multiparametric approach, is linked to a higher risk of cardiovascular events and may improve risk stratification in MVP, even in those without significant MR.
Achieving an Optimal Outcome After Stage 1 Palliation for Hypoplastic Left Heart Syndrome and Variants: Frequency, Associated Factors, and Subsequent Outcomes
Authors: Shalhoub Khayri , Heydarian Haleh C. , Hanke Samuel P. , Cnota James F. , Stein Laurel H. , Tepe Brooke , Hill Garick D.
Published: June 2024

Background

We sought to measure frequency of achieving an optimal outcome after stage 1 palliation (S1P) for hypoplastic left heart syndrome and variants, determine factors associated with optimal outcomes, and compare outcomes after stage 2 palliation (S2P) using the National Pediatric Cardiology Quality Improvement Collaborative database (2008–2016).

Methods and Results

This is a retrospective cohort study with optimal outcome defined a priori as meeting all of the following: (1) discharge after S1P in <19 days (top quartile), (2) no red flag or major event readmissions before S2P, and (3) performing S2P between 90 and 240 days of age. Optimal outcome was achieved in 256 of 2182 patients (11.7%). Frequency varied among centers from 0% to 25%. Factors independently associated with an optimal outcome after S1P were higher gestational age (odds ratio [OR], 1.1 per week [95% CI, 1.0–1.2];
P
=0.02); absence of a genetic syndrome (OR, 2.5 [95% CI, 1.2–5];
P
=0.02); not requiring a post‐S1P catheterization (OR, 2.7 [95% CI, 1.5–4.8];
P
=0.01), intervention (OR, 1.5 [95% CI, 1.1–2];
P
=0.006), or a procedure (OR, 4.5 [95% CI, 2.8–7.1];
P
<0.001) before discharge; and not having a post‐S1P complication (OR, 2.7 [95% CI, 1.9–3.7];
P
<0.001). Those with an optimal outcome after S1P had improved S2P outcomes including shorter length of stay, less ventilator days, shorter bypass time, and fewer postoperative complications.

Conclusions

Identifying patients at lowest risk for poor outcomes during the home interstage period could shift necessary resources to those at higher risk, alter S2P postoperative expectations, and improve quality of life for families at lower risk.
Youth and Prayer in a Secular Age
Authors: Ellis Wesley W.
Published: June 2024

This article diagnoses the difficulty of prayer for young people inhabiting a secular society and offers the beginnings of a theology of prayer for this context. For young people in the United States, our secular age is defined by immanence, excessive positivity, and dynamic stabilization that constitute anxiety as a primary motivator that leads to burnout and exhaustion. Prayer as communion with God offers a corrective that can relieve anxiety and offer renewal. For this, prayer must not be thought primarily as a human action, but a divine action. In prayer, we do not grasp God, we are grasped by God. As such, prayer is a grace young people need, and its teaching must become the primary pastoral vocation in a secular age.
Review of the Afrotropical members of the genus Eridachtha Meyrick, 1910 (Lepidoptera: Lecithoceridae: Lecithocerinae), with descriptions of 12 new species
Authors: PARK KYU-TEK , MINET JOËL , KOO JUN-MO , YU TAE-UK
Published: June 2024

The genus Eridachtha Meyrick, 1910 of the subfamily Lecithocerinae is revised for the Afrotropical region. Twelve new species are described within it: six from Kenya (Eridachtha campanella Park, sp. nov., E. cardialis Park, sp. nov., E. centriella Park, sp. nov., E. crococorypha Park, sp. nov. (which also occurs in Uganda), E. nairobiensis Park, sp. nov., and E. phiarella Park, sp. nov.), two from Tanzania (E. arumeruna Park, sp. nov. and E. kilimanjaroensis Park, sp. nov.), three from Uganda (E. pholexana Park, sp. nov., E. cupaformis Park, sp. nov., and E. atrihispida Park, sp. nov.), and one from South Africa (E. capensis Park, sp. nov.). Three of them (whose males remain unknown)—E. cupaformis, E. atrihispida and E. crococorypha—share with E. gymnopalpa (Janse, 1963), comb. nov., a yellowish-orange ground colour of the forewing, and are thus grouped in the E. gymnopalpa species-complex. Additionally, the genus Atrichozancla Janse, 1954, syn. nov. hitherto composed of three species (A. phaeocrossis (Meyrick, 1937), A. cosymbota (Meyrick, 1920), and A. gymnopalpa Janse, 1963), is synonymized with the genus Eridachtha on the basis of wing venation and genital characteristics. The adults and genitalia of the new Afrotropical species are illustrated, as well as those of E. calamopis Meyrick, 1920 and E. phaeochlora Meyrick, 1920.
Blow flies (Diptera: Calliphoridae) of the Baja California Peninsula
Authors: STOTELMYRE LYLE MAGEE
Published: June 2024

The blow fly fauna of the Baja California peninsula, Mexico has been sparsely documented. This study incorporates and lists recent and historical records of blow flies from collecting trips throughout the peninsula, visits to major southern California museums for historical collection records, and a literature search. Seven genera and 16 species are reported from the two peninsular Mexican States, Baja California, and Baja California Sur. Three species are recorded that are not included in the 2020 Catalog of Mexican Calliphoridae by Jaume-Schinkel, & Ibanez-Bernal (2020), they are: Calliphora livida, Calliphora terraenovae, and Calliphora vomitoria. One blow fly species, Cochliomyia hominivorax (the primary Screw-Worm Fly) is not included here but is found in museum collections. Once present in Baja, it is considered eradicated from continental North America as far south as the Panama Canal by the U.S. Department of Agriculture (USDA) however, it is occasionally reintroduced (Skoda et al. 2018) and is still present in some Caribbean islands. It is noteworthy that all calliphorid species from this mountainous desert peninsula are also found in the State of California, USA which supports 11 genera and 47 species in this family (Whitworth 2006) primarily because of its more varied climate and terrain. The Baja peninsula can be considered a southern extension of the State of California, with reduced species representation due to reduced climate and terrain variation, so no separate identification keys are necessary. Forensic entomologists and taxonomists can use the blow fly keys for North America by Whitworth, 2006, and 2017 for this region. The latest key by Jones, Whitworth, and Marshall (2019) is revolutionary and much welcome in taxonomy in that it is an online computer-aided key that has actual macro-photos of species identification characters and is intended to be used with a computer screen next to your microscope for identifications in place of printed material.
A new species of the genus Tarehylava Stroiński, 2021 (Hemiptera: Fulgoromorpha: Ricaniidae) from southern Madagascar
Authors: GNEZDILOV VLADIMIR M.
Published: June 2024

A new species of the ricaniid genus Tarehylava Stroiński, 2021, T. gorgona sp. nov., is described from the Androy Region of Madagascar. Male genitalia structure of the genus Tarehylava is described for the first time. The relationships of Tarehylava within Ricaniidae are discussed.
Generative AI in Technical Communication: A Review of Research from 2023 to 2024
Authors: Reeves Carol , Sylvia J.J.
Published: June 2024

Since its release in late 2022, ChatGPT and subsequent generative artificial intelligence (GAI) tools have raised a wide variety of questions and concerns for the field of technical communication: How will these tools be incorporated into professional settings? How might we appropriately integrate these tools into our research and teaching? In this review, we examine research published in 2023–2024 addressing these questions ( N = 28). Overall, we find preliminary evidence that GAI tools can positively impact student writing and assessment; they also have the potential to assist with some aspects of academic and medical research and writing. However, there are concerns about their reliability and the ethical conundrums raised when they are used inappropriately or when their outputs cannot be distinguished from humans. More research is needed for evidence-based teaching and research strategies as well as policies guiding ethical use. We offer suggestions for new research avenues and methods.
Scripts of Security: Between Contingency and Obduracy
Authors: Pelizza Annalisa , Aradau Claudia
Published: June 2024

The special issue on Scripts of Security proposes to advance interdisciplinary exchanges between Science and Technology Studies and Critical Security Studies. While performativity, enactment, and intra-action have opened important questions about the messiness of security practices and the contingency of their effects, there has been less attention to the obduracy of institutionalized agency and how continuities and asymmetries of power are reproduced, challenged, and maintained. This Special Issue proposes to revisit and rework the notion of script and the related analytical toolkit to make sense of both contingency and obduracy in the technopolitics of security. The contributions gathered here make three interventions in order to account for contemporary challenges posed by the increasing securitization of diverse sociotechnical practices. Firstly, they update, integrate, and reconfigure the notion of script and its associated toolbox to account for the specificities of security practices. Secondly, the articles revisit critical analyses of security in light of the notion of script. Finally, they show how such an updated notion of script can hold together accounts of contingency and obduracy and not jettison one at the expense of the other.
Numerical and experimental studies on dissimilar joining of Hastelloy C-276 and SS-316L using microwave hybrid heating at 2.45 GHz
Authors: Reddy Kadapa Vijaya Bhaskar , Shankar K.V. Hari , Gudipadu Venkatesh , Mishra Radha Raman
Published: June 2024

Dissimilar joints of SS-316L and C-276 (Hastelloy) were developed using C-276 powder with microwave exposure 600 s in microwave applicator (2.45 GHz, 900 W). A multi-physics model was validated with experimental studies and simulation were carried out to analyse the microwave-joint interaction characteristics. The simulation results showed that a concentrated electric field (5.86 × 104 V/m) and higher resistive losses (3.07 × 107 W/m3) at the joint region facilitated rapid heat generation locally. Microstructural characterization of the joint revealed the formation of cellular grains such as Fe-Ni intermetallic phases with Mo, Cr and W-carbides along the grain boundaries. Joints exhibited average microhardness of 290 HV, and tensile strength of 425 ± 10 MPa and 14% elongation with failure due to both ductile and brittle fracture modes.
Investigative studies on natural fiber reinforced composites for automotive bumper beam applications
Authors: Wagh Jayashri Pawar , Malagi Ravindra R , Madgule Mahadev
Published: June 2024

The automotive sector wants lighter, recyclable, degradable, and sustainable composite materials. In the last few decades, natural fiber composite has been used in a wide range. The natural plant-based fibers are reinforced into polymeric composite materials, giving significant mechanical properties compared to conventional material. This work selects flax and sisal fibers due to higher strength and Young’s modulus. Mechanical behavior such as tensile, flexural, and impact strength are evaluated. Mechanical behavior results are considered in the simulation to determine the performance of an automotive bumper beam. The tensile strength of the flax composite is 90% higher than that of the sisal composite. Flexural strength is 17% higher in a flax composite, whereas energy absorption is nearly identical in a flax and sisal composite. The flax composite has a maximum 204.9 MPa tensile strength, 157.98 MPa flexural strength, and 45 J energy absorption. The mechanical behavior results are validated with simulation results in the ANSYS workbench for static analysis. The results indicate that the flax fiber reinforced composite with 43:57 of a flax-matrix ratio performs better as it can be used as a structural material. A morphological study shows the uniform distribution of matrix material and fiber orientation.
Reconstructive Septorhinoplasty for Surgical Correction of Tessier's No. 0 Cleft in Adult Patients
Authors: Sazgar Mehr A. , Sazgar Amir A.
Published: June 2024

Background

Tessier No. 0 cleft, characterized by a bifid nose, significantly impacts facial development, imposing significant psychological and financial burdens on patients. Correction lacks consensus due to varied presentations and limited documentation of surgical treatments, notably in adults.

Solution

Loco-regional soft tissue flaps can address minor deformities, but establishing a robust skeletal framework is often crucial for permanent correction.

Innovation

This article introduces a novel and effective approach through reconstructive septorhinoplasty for addressing this anomaly.