bluuebunny/crossref_metadata_2025 huggingface dataset:
Unveiling Drug Discovery Insights through Molecular Electrostatic Potential Analysis
Authors: Suresh Cherumuttathu , Haritha Mambatta
Published: November 2024

Molecular Electrostatic Potential (MESP) analysis has emerged as a pivotal tool in drug discovery, providing insights into molecular reactivity and noncovalent interactions essential for drug function. While widely used MESP-on-isodensity surface analysis offers interpretations of electron-rich or deficient regions of a drug molecule, the MESP topology parameters such as spatial minimum (Vmin) and MESP at nuclei (Vn) provide a quantitative understanding. The investigation into the correlation between MESP parameters and various molecular properties such as lipophilicity, pKa (acidity/basicity), conformations, and tautomeric forms is crucial for understanding the impact on biological activity of drugs and facilitating drug design. Moreover, MESP topology analysis serves as a fundamental tool in elucidating the pharmacological behavior of compounds and optimizing their therapeutic efficacy. A quantitative study utilizing Vn parameters to assess the hydrogen bond propensity of a drug presents a novel strategy for investigating drug-receptor interactions with increased precision. The qualitative and quantitative analysis of the MESP features of various drugs, including their applications in cancer, tuberculosis, tumors, inflammation, and infectious diseases such as malaria, bacterial infections, fungal infections, and viral infections, is conducted in this review.
Synthesis of Robust Phosphazane Hybrid NHCs for Small Molecule Activation: Unique sp2 and sp C–H insertion.
Authors: Hum Gavin , Zhang Ziyun , Ong How Chee , Đorđević Nemanja , Khoo Yi Xin Joycelyn , Li Yongxin , Daley-Dee Patrick R. , Stuparu Mihaiela C. , Huynh Han Vinh , Falivene Laura , García Felipe
Published: November 2024

The ability of chemists to master catalysis and small molecule activation can be largely attributed to the rational design of a wide range of tunable ligand frameworks. Striking results in this area have been achieved using N-heterocyclic carbenes (NHCs) due to their tunable steric and electronic properties. Among these systems, NHCs with inorganic backbones have demonstrated significant potential in these areas due to their distinctive electronic properties compared to their organic counterparts. Within this group, phosphazane hybrid NHCs (PHNHCs) species have been proposed as highly versatile and promising species for reactivity and catalytic studies. However, their application in the realm of small molecule activation has been largely underexplored due to the high intrinsic electrophilic nature of their phosphorus centers. In this study, a decade after their first literature report, we successfully synthesized a series of robust PHNHCs. These new systems exhibit notable electronic characteristics, showing high net donor strength (TEP = 2048 cm–1) and appreciable π-acceptor properties (δse = 269 ppm in CDCl3; δse = 299 ppm in (CD3)2CO). Furthermore, the free carbenes of PHNHCs demonstrate the ability to insert into C–H bonds of both olefins and alkynes. Notably, the olefin insertion has not been previously observed in other NHCs. This unique reactivity profile positions PHNHCs as a valuable and complementary addition to the existing NHC toolkit.
Efficient nickel precatalysts for Suzuki-Miyaura cross-coupling of aryl chlorides and arylboronic acids under mild conditions
Authors: Stewart Scott , John Morgan , Nutt Michael , Offer Josephine , Duczynski Jeremy , Yamazaki Ken , Miura Tomoya , Moggach Stephen , Koutsantonis George , Dorta Reto
Published: November 2024

The synthesis and catalytic properties of Ni(II) complexes, with the general formula Ni(NHC)[P(OR)3](Ar)Cl is described. These complexes are air-stable and extremely effective precatalysts in the Suzuki-Miyaura cross-coupling reaction. The reaction protocols described allow for the cross-coupling of aryl chlorides and arylboronic acids, employing low catalyt-ic loading, to deliver a large variety of functionalized biaryl compounds. For the coupling of aryl chlorides with N-heterocyclic boronic acids, TBAF was used as an additive to afford aryl-N-heterocyclic products. Overall, these cross-coupling protocols operate at room or mild temperatures and can be applied to a variety of electronically and sterically differentiated coupling partners. Fundamental insights into the mechanism of this reaction, including the proposed for-mation of the catalytically active Ni(NHC)[P(Oi-Pr)3] and resting state species are also reported.
Hypothesis of Concerted Reactivity of Singlet Non-Covalent Radical Dimers
Authors: Molev Gregory
Published: November 2024

This work explores the intriguing domain of Frustrated Radical Pairs (FRPs) and their potential to form non-covalent dimers, termed Entangled Radical Pairs (ERPs), which exhibit unique singlet ground states and potential concerted reactivity, differing from traditional stepwise reactions. A few recent publications showed that in certain cases when two radicals cannot form a covalent bond, they unexpectedly form a non-covalent dimer with a singlet ground state. This potentially opens a new elusive route of FRPs’ reactivity, in which both radicals react simultaneously as one molecule. Here, we review several published articles, in which such reactivity probably took place, but was overlooked. The idea presented in this proposal suggests a path towards many interesting reactions, such as low-temperature metal-free dehydrogenation of aliphatic hydrocarbons and others. Additionally, an alternative mechanism for the reactivity of Frustrated Lewis Pairs (FLPs) based on the ERP framework is proposed. Lastly, the implications of the ERP model on the general theory of chemical bond formation are contemplated, suggesting a revision of the traditional views on hybridization and electron entanglement. The manuscript calls for further experimental and theoretical investigations to substantiate the presented hypotheses, aiming to unlock new pathways in radical chemistry and beyond.
Intramolecular Magnetic Exchange Interaction in Dichalcogenide Substituted Organic Diradical Dications
Authors: R Nath Abhishek , Kumar Manish , Ali Md. Ehesan
Published: November 2024

Organic diradical dications, due to reduced intermolecular interactions, exhibit a greater tendency to adopt high spin states in the solid phase compared to their neutral diradical counterparts. This characteristic makes them promising candidates for applications involving organic electronics. We present a theoretical study of a recently synthesized sulfur-based diradical dication, a unique system exhibiting a robust triplet ground state. Using a number of density functional theory (DFT) based methods (e.g. standard broken-symmetry DFT, constrained DFT, spin-flip TDDFT) and wavefunction-based multi-reference CASSCF+NEVPT2 methods, we investigate its magnetic properties and explore the influence of chalcogen substitution on the magnetic exchange coupling. An active space scanning method was adopted to overcome the difficulties in choosing the correct active space for multireference calculation. Our findings highlight the critical role of multi-reference methods in accurately capturing the magnetic behavior of highly pi-conjugated systems. The study reveals a surprising variation in magnetic properties among sulfur, selenium, and tellurium-based diradical dications, despite being elements of the same group. These results offer valuable insights into the design and tuning of magnetic properties in organic diradical dications.
Prevalence of Accessory Canals in the Furcation Area
Authors: Manoranjan S.J Dr , Ashish Yadav Dr , Mohamed Faizuddin Dr
Published: November 2024

None
A study on comparison of nutritional status between dentate and non-dentants adults
Authors: Smitha BK Dr , Harikiran AG Dr , Ashok Kumar BR Dr , Nagesh KS Dr
Published: November 2024

None
Editorial
Authors: K S Nagesh Dr
Published: November 2024

None
Evaluating the efficacy of 5% Sodium Calcium Phosphosilicate containing dentifrice when used for treatment of dentin hypersensitivity- A Pilot Study
Authors: Harikiran A.G Dr , Pallavi S.K Dr , Rupali Lav Dr , Sangeeta Dr. , Chitrapriya K Dr
Published: November 2024

None
Peripheral Odontogenic Fibroma: Report of a Rare Case
Authors: Asha R Iyengar Dr , Rishabh Kapila Dr , K S Nagesh Dr , Seema Patil Dr
Published: November 2024

None
Orofacial Burn and its prosthetic Management- A Review
Authors: Prasad D Krishna , Shetty Manoj , Nayak Nagar Smitha , Hedge Chetan
Published: November 2024

None
Fiber Posts and the silane as an adhesion promotor
Authors: Madhu Pujar Dr.
Published: November 2024

None
Influence of Smoking on Fibroblast apoptosis in chronic peridontits
Authors: S Shivanaikar Sachin , Mohamed Faizuddin Dr , Kishore G Bhat Dr
Published: November 2024

None
Dentinal Changes in Attrition and Abrasion – A Scanning Electron Microscopic Study
Authors: M G Madhura , Manohar Ram
Published: November 2024

Objectives To observe the dentinal changes in attrited and abraded teeth under light microscope and Scanning electron microscope SEM. Material and methods Twenty extracted permanent teeth 10 attrited 6 abraded anteriors and 4 normal teeth were chosen. The teeth were fractured along their longitudinal axes after fixation in 10 formalin. One fractured half of each tooth was prepared into a ground section for light microscopy and the other complementary half was utilized for scanning electron microscopy. Results The formation of dead tracts and variable amounts of reparative dentin were seen in all cases of attrition and abrasion under light microscopy. Under SEM the areas of dead tracts showed the presence of affected tubules with roughened walls and margins caused by small globular calcifications. Smaller areas resembling dentinal sclerosis seen in few abraded teeth under transmitted light could not be identified by SEM. Complete occlusion of dentinal tubules was not seen in these areas. The reparative dentin seen under transmitted light appeared as an irregular mass of tissue without discernible peritubular and intertubular dentin under SEM. Conclusion The presence of crystals and globular calcifications within and on the walls of diseased dentinal tubules in dead tract areas obstruct the passage of light by reflection refraction and scattering giving rise to the optical effect under light microscope. The reparative dentin under SEM showed irregular mass of tissue devoid of intertubular and peritubular dentin. No identifiable changes for dentinal sclerosis were detected under SEM.nbsp
Prevalence and Comparison of Periodontopathic Bacteria in Aggressive And Chronic Periodontitis Patients- A Microbiological Study
Authors: L Jyothi , Rao Tirumal , Kumar Rakesh
Published: November 2024

Specific bacterium or a group of bacteria are found to be responsible for causing periodontal destruction and are associated with specific forms of disease. This study was carried out to determine the prevalence and comparison of periodontopathic bacteria in the subgingival bacterial sample of plaque of patients with aggressive AgP and chronic periodontitis CGP.This study was carried out in a total of 40 patients divided into two groups-patients diagnosed with aggressive periodontitis and the other with chronic periodontitis. Pooled subgingival plaque samples were obtained with a sterile curette from the deepest pocket in each quadrant and transported to the laboratory for biochemical analysis for species identification. The prevalence of P.gingivalis P.intermedia F.nucleatum and T.forsythus was greater in CGP than AgP. A.actinomycetemcomitans was most prevalent and isolated at a greater frequency from LAgP. However A.a could not be isolated from any subjects with CGP. Statistical analysis of the data showed a significant difference between CGP and LAgPwhen mean counts of the bacteria was considered. There was not much difference in the specificity of major periodontopathic bacteria in CGP and GAgP. Identification of microbiota in the subgingival environment alone could not differentiate between different periodontal diseases. Further studies are required to identify particular strains of these periodontopathic bacteria that are responsible for tissue destruction.
Functional and Esthetic Rehabilitation of a Patient with Amelogenesis Imperfecta - A Case Report
Authors: Bawa Shamina , N. Hegde Mithra
Published: November 2024

Amelogenesis Imperfecta is a hereditary condition where enamel formation is disturbed resulting in defects in mineralization or matrix formation. This case presentation deals with the multidisciplinary approach to rehabilitate a case of amelogenesis Imperfecta of the hypo calcified type. The aim of the treatment was to save the remaining teeth preserve the tooth structure as much as possible while preventing further tooth loss maintain and improve masticatory function and to improve the esthetics.A systematic and sequential interdisciplinary treatment approach was carried out and the patients functional and esthetic requirements were fulfilled.
Crown Lengthening for Esthetics and Retention: An Overview & Case Series
Authors: Devanoorkar Archana , G Nagappa. , Aspalli Shivanand , Shetty Sudhir
Published: November 2024

Aesthetics remains an inseparable part of todays periodontal practice because of patients greater health expectations and increasing cosmetic awareness. One such important aspect of periodontal treatment is crown lengthening procedure for esthetics and function. Surgical crown lengthening is necessary in few cases that may present with sub gingival or sub-crestal extension of tooth fractures carious lesions or previously placed restoration margins. Inappropriate decision making may result in the violation of biologic width and subsequent gingival inflammation and bone loss. So as to avoid such unfavorable consequences crown lengthening procedure is considered to preserve the biologic width by providing a space of 3mm between the gingival margin and alveolar bone crest. This procedure not only enhances the esthetics but also enhance the retention of the prosthesis. In addition crown lengthening is also performed for the correction of the excessive gingival display. As we know that pleasant smile enhances the beauty of a person thus increases patients self-confidence and the quality of life. Here are few case reports of functional and esthetic crown lengthening techniques considering various factors that are to be addressed prior to the procedures.
Scanning Electron Microscopic Evaluation of Composite Resin-Dentin, liner-Dentin Interfacial Gap with Composite Resin Restora
Authors: Kumar VC Sunil , PR Pradeep , Vijetha Badami , Rao B Sunil , M Manjunatha
Published: November 2024

The aim of the present study was to compare marginal sealing capacity of adhesive restorative system and combination of this system with different lining materials. Thirty non carious third molars were used in the present study. 2mm deep heels were made on the surfaces at the level of cemento enamel junction and specimens were then ground flat until the heels disappear. The teeth were randomly divided into 3 groups of ten each. A thin layer of calcium hydroxideglass-ionomer resin modified glass-ionomer liner was applied over exposed dentinal surfaces adjacent to area of pulp chamber. The remaining exposed dentinal surfaces were etched with etchant gel. Single Bond 2 adhesive was applied over calcium hydroxideglass-ionomer resin modified glass-ionomer liner and etched dentinal surfaces and photo cured for ten seconds. Alayer of composite resin not more than 2mm was applied to dentinal surfaces and light cured for 40 seconds. Results indicated calcium hydroxide lining material had highest degree of interfacial gap and differed significantly from glass-ionomer lining cement and resin modified glass-ionomer liner. Composite resin- dentin interface showed a gap free attachment hybrid layer and resin tag penetration at X 3000 magnification.
Treatment of Class II Malocclusion Crowding using Self−Ligating Brackets and MPA IV - A Case Report
Authors: U.S Pavithra , M Ravi , C Ashish
Published: November 2024

None
Skeletal Pattern Assessment by Orthopantomograph
Authors: C. Patil Basanagouda , . Padmini , Sakri Mohan , T Suma , R Desai Shrikar , KS Girish
Published: November 2024

Background amp Objectives Panoramic radiography is frequently used in orthodontic practice to provide information about the teeth their maturation period and axial inclinations and surrounding tissue. The objectives of this study were to find out whether panoramic radiographs can be used to investigate skeletal pattern compared to lateral ndash cephalograms.Methods Panoramic radiographs and lateral cephalograms of 30 patients 14 males. 16 females with Class II dental and skeletal malocclusions were taken under standard conditions. Only angular measurements were taken and the readings from the cephalogram and OPG were correlated.Results The OMAND Co-McMc-Me showed a positive linear correlation with gonial angle Ar-GoGo-Me. The OCOND Co-McMc-FMe showed a negative linear correlation to the mandibular plane angle Go-Gn to Sn. The OMAND Co-McMc-Me showed a positive linear correlation with condylar inclination angle Co-GoGo-Me. A negative correlation was found between UOCCL and FHU6-U1 and LOCCL angle L6-L1-L6 and the FHL6-L1. Comparison of the palatal plane mandibular plane and condylar inclination angles between the right and left sides in the OPG were statistically insignificant. Conclusion The results of this study indicate that OPG can be used as an investigative tool in quantitative assessment of malocclusion. Angular measurements of the OPG can be used as a substitute for corresponding angular measurements from the lateral cephalogram both for dental as well as skeletal parameters.
Assessment and Correlation of Single Stranded DNA Damage in Oral Squamous Cell Carcinoma with Broder's Histopathological Grading
Authors: Bhagwath Sundeep , Chandra Lokesh
Published: November 2024

Early detection of oral squamous cell carcinoma OSCC can prevent significant morbidity and can also increase the life expectancy of patients. Many methods have been devised to this effect but most are time consuming and expensive. Since DNAdamage is one of the principle features in cancer development assessment of DNA damage is an important prognostic indicator in patients with cancer. Single cell gel electrophoresis SCGE assay also known as Comet assay is a sensitive quick and cost effective method of detecting single stranded DNA damage in cells.The present study was carried out on the assumption that oral mucosal cells could show the DNA damage in OSCC. For this study smears were taken from lesion proper of 30 patients with OSCC and from the buccal mucosa of 30 normal healthy volunteers. This study was undertaken to evaluate the extent of DNA damage in oral smears of patients with OSCC and to determine correlation if any of the extent of DNA damage to Broders histopathological grading of OSCC. The mean DNA damage levels of both the groups were measured and statistically analyzed with students t test. A high statistical significance of p lt 0.0001 was found in DNA damage levels of oral mucosal cells between normal subjects and patients with OSCC. AStepwise increase in DNAdamage levels was also seen between the different grades of OSCC and statistical significance at p lt 0.0001 was found between all the grades by employing the one way Anova F technique.The findings of statistically significant increased DNA damage levels in oral mucosal cells in OSCC patients and their correlation to Broders histopathological grading suggest that comet assay may be used effectively to assess the prognosis of OSCC.
Treatment of Periapical Lesions using a Combination of Bone Graft and Platelet-rich Fibrin
Authors: Kumar R Vinaya , Subhashini N , Kini Annapoorna , K G Nischith
Published: November 2024

Cohn 1998 proposed periapical surgery as a predictable option when root canal treatment is either not possible or fails. Bone grafts and bone regeneration materials are being used in periapical surgery with varying degrees of success. Calcium phosphate biomaterials have excellent tissue compatibility and do not elicit any inflammation or foreign body response. However the key to tissue regeneration is to stimulate a cascade of healing events that can result in the completion of integrated tissue formation. This is possible only with the use of biological mediators as they induce bone regeneration by osteoinduction while grafts induce regeneration by osteoconduction. The need for these biological modulators led to the development of Platelet-Rich Fibrin PRF by Choukroun et al. in 2001. This clot combines many healing and immunity promoters present in the initial blood harvest. Its natural fibrin architecture seems responsible for a slow release of growth factors and matrix glycoproteins during ge7 days Dohan 2009. The objective of this case report was to evaluate the bone regeneration in endodontically induced periapical lesions using PRF in combination with synthetic TCPand calcium hydroxyapatite bone graft material for a period of 9 months.
Aggressive Periodontitis & Multiple Supernumerary Teeth - A Rare Presentation
Authors: Warad Shivaraj , S Kolar Sahana , C Koregol Arati , Kalburgi Nagaraj
Published: November 2024

Aggressive periodontitis comprises a group of rare often severe rapidly progressive form of periodontitis with a distinct tendency for familial aggregation. Simultaneous Presence of multiple supernumerary teeth in generalized aggressive periodontitis cases is a rare condition. Scanty of literature available till today have reported supernumerary premolars in aggressive periodontitis cases. Here we report a rare case of generalized aggressive periodontitis associated with multiple impacted supernumerary permanent teeth in relation to molars.
“The illiterate of the 21st century will not be those who cannot read and write, but those who cannot learn, unlearn, andrelearn. ” ― Alvin Toffler
Authors: Roopa R Nadig Dr
Published: November 2024

None
Efficacy Of Different Final Irrigation Techniques On The Removal Of Smear Layer From The Root Canal – A Scanning Electron Microscopic Analysis
Authors: Chowdary V Avanthi , Mathew Sylvia , Sreenivasa Murthy B.V , P Karunakar , Hegde Swaroop , N Shruthi
Published: November 2024

Aim The purpose of this study was to compare the efficacy of the F-file in removing the smear layer from the instrumented root canal and compare it to passive ultrasonic irrigation and conventional needle syringe irrigation.Materials amp Method Sixty freshly extracted intact caries free human teeth with straight single canal and mature apices were collected. Access cavities were prepared followed by working length determination and rotary instrumentation of the canal with ProTaper system up to size F3. The teeth were divided in to three groups of 20 teeth each depending upon the final irrigation regimen it received Group Andashneedle irrigation with 17 Ethylene Di amine tetra acetic acidEDTA 5.25 Sodium Hypochlorite NaOCl Group B ndash Passive ultrasonic agitation of 5.25 NaOCl and Group C ndash 5.25 NaOCl F-File. The teeth were decoronated the roots were split longitudinally and the sections examined under scanning electron microscope for the presence of smear layer at the coronal middle and apical thirds of root canals and scored.Results Mean scores for smear layer were calculated and statistically analyzed p lt 0.05. F-file scored least for smear layer and the difference among the three groups was statistically significant. All the groups recorded highest score for smear layer at the apical third. Conclusion F-file can be a time and cost efficient alternative to passive ultrasonic irrigation as a final irrigation regimen in straight root canals.
Evaluation And Comparison Of Amount Of Dentin Removed After Retreatment Using Three Different Retreatment Methods: An In-vitro Study
Authors: Sreejith Mr , B.S.Keshava Prasad Dr. , Shashikala K
Published: November 2024

Introduction The aim of the present in-vitro study was to evaluate and compare the amount of dentine removed by Protaper Universal Retreatment System Files Profile. 04 files and Hand K files after retreatment. MethodologyA total of 48 freshly extracted human teeth with single canal were prepared using crown down technique. The specimens were then mounted on acrylic blocks and digital radiographs were made in the mesio-distal and labio-lingual plane. Later the specimens were obturated with lateral condensation with AH plus sealer. The teeth were then randomly divided into 3 groups n16 and retreated using Protaper Retreatment files Profiles .04 and Stainless Steel Hand k files respectively. Retreatment was considered complete when no filling material was observed on the instruments. Digital radiographs of the retreated specimens were made in the mesio-distal and labio-lingual plane.All the samples were analyzed for amount of dentin removed using a digital image analyzing software Image ProExpress Version 6.0.The area of dentin removed were calculated by subtracting the area of dentin after cleaning and shaping and area of dentin after retreatment. Mean dentin removal of all three files after retreatment were compared using Two way ANOVAtest and multiple comparisons between the groups were done using Bonferroni test.Results and conclusionThe study was concluded that Stainless Steel Hand K files removed less amount of dentin followed by Profile .04 files and maximum dentin removal was exhibited by Protaper Universal Retreatment Files.nbsp
Dermatoglyphics Of Dental Caries And Periodontal Diseases In Children Of North Karnataka
Authors: Shweta Advani Dr. , GA Raviraj , Sogi Suma , Hugar Shivayogi , K Kiran , P Kumar Shashank
Published: November 2024

Background Dental caries and periodontal diseases have always known to be infectious diseases of multifactorial origin. Genetic susceptibility can be considered as one of the factors. But evaluating genetic susceptibility has always been a concern. This genetic susceptibility can be evaluated using dermatoglyphics. Aim Of this scientific paper is to determine if there is any significant correlation between dermatoglyphics and the infectious oral diseases like dental caries and periodontal diseases.Materials And Method A total of 96 children were divided into 6 groups for assessing two infectious oral diseases. 48 children were divided into 3 groups according to caries rate. The other 48 children were divided into 3 groups according to the OHI score. They were assessed for their finger tip and palm patterns.Statistical Analysis It was done using the ANOVA Test.Results As caries increased there was increase in whorls and decrease in loops and as the calculus and debris increased more prone to periodontal diseases there was a decrease in loops and no significant relationship with whorls.Conclusion There is a significant relationship between genetics and infectious oral diseases upto a certain extent but further research is required.nbsp
Goldenhar Syndrome: A Case Report
Authors: Peeyush Shivhare Dr. , Lata Dr. , Kumar TS Mahesh , Gupta Ashish
Published: November 2024

Goldenhar syndrome GS also known as oculoauriculovertebral dysplasia is a relatively common developmental disorder characterized by craniofacial anomalies in association with ocular auricular vertebral cardiac renal central nervous system and maxillofacial defects. This condition was first described in 1952 by the Swiss ophthalmologist Maurice Goldenhar. The incidence of this condition varies from 1 in 3500 to 1 in 5600 live births. Goldenhar syndrome needs a multidisciplinary approach regarding craniofacial and cardiologic associations. We are presenting a case of 19 year old male who was diagnosed with Goldenhar syndrome.
Aerated Soft Drinks: Its Effects On Cement Solubility
Authors: RAJESWARI C L Dr. , Kumar MV Sunil , Manvi Supriya , G Srivatsa
Published: November 2024

Aim The purpose of this study is to evaluate the effect of aerated soft drinks on cement Solubility of different luting cements.Materials and Methods Four types of luting agents Resin cement Polycarboxylate Glass ionomer cement and Intermediate restorative material were used in the study. Cements were mixed according to manufacturers instructions and specimens were made. These specimens were weighed before and after 24 hours after placing them in commonly consumed aerated soft drinks i.e. Coca cola Limca Maaza and Distilled water was used as the control.Result The results indicated a statistical significance in the loss of mass of the cement after 24 hours of immersion of all four cements in Coco cola Resin cement Glass ionomer cement and Polycarboxylate in Limca and Intermediate restorative material in Maaza at 10 level of significance plt0.01.Conclusion All the luting cements showed increased solubility when immersed in aerated soft drinks. Resin cement showed the least solubility among all cements compared and no significant changes were observed for all cements in distilled water.nbsp
Smile Celebration-Minimally Invasive Cosmetic Dentistry Coupled With Computer Guided Occlusal Analysis. (a Case Report)
Authors: Thumati Prafulla , H Saritha , G Harish
Published: November 2024

Evidence of dentistry dates back to 7000 B.C and since then has come indeed a long sophisticated way. There have been admirable advances in the field of Prosthodontics enabling production of artificial teeth that feel function and appear nothing but natural. The following case report describes the management of maxillary edentulousness and Mandibular teeth attrition using the concept of Minimally Invasive Cosmetic Dentistry MICD with Ceramopolymer Ceramage a new age restorative material. Computer Guided Occlusal Analysis CGOA was used to guide sequential occlusal adjustments to obtain measurable bilateral occlusal contact simultaneity.
Caries Prevalence And Risk Assessment – A Survey
Authors: Ali Habibullah Mohammed , S. Bhat Sham , Hegde K Sundeep
Published: November 2024

Dental caries and its consequences together constitute a very real and personal problem for almost every man woman and child. . The prevalence and incidence of dental caries in a population is influenced by a number of risk factors such as age sex dietary patterns and oral hygiene habits.nbsp nbsp nbsp nbspThe prevention of disease is the most perfect form of practice. Prevention of the disease rests on knowledge of the disease etiology as well as an understanding of the occurrence and distribution of related factors and conditions. Information on caries prevalence and severity forms of caries prevention programs and treatment needs in a population. Therefore a continuous need remains to field caries prevalence and severity information.nbsp nbsp nbsp nbspThe present study was undertaken to study the prevalence of dental caries in school children 6-12 years of age and association of caries with factors like age sex diet sweet consumption mode of tooth cleaning and oral cleanliness.nbsp nbsp nbsp nbspThis will enable public health authorities to plan and implement interventions to improve the oral health of this population. With limited resources availability the need for prevention cannot be over emphasized.
Management Of Crown Root Fracture Of Maxillary Central Incisors – A Multidisciplinary Approach: A Case Report And An Overview
Authors: Kumar K Naveen , N Hegde Mithra , Hegde Priyadarshini , Shetty Shishir
Published: November 2024

This case report describes the successful management of complicated crown root fracture of maxillary central incisors and their subsequent treatment to restore form function and esthetics. A 26 year old female had fractured her maxillary central incisors. The right central incisor had fracture which involved mesial 23rd of the crown and the maxillary left central incisor had fracture line which extended distally with fracture fragment still in place. The teeth were first endodontically treated orthodontically extruded crown lengthening was done with apically displaced flap and ostectomy followed by which a post and core therapy was performed and a final restoration was given. This article presents the infrequently utilized treatment method of orthodontic extrusion and how it can serve as an alternative to the sacrifice of the natural root system.
Semantik Warna dalam Bahasa Indonesia dan Bahasa Jepang
Authors: Rika Atta , Mulyadi Mulyadi , Malayu Siti Muharami
Published: November 2024

Penelitian ini bertujuan untuk mendeskripsikan warna dasar (primer) dan turunan (sekunder) dalam bahasa Indonesia dan bahasa Jepang serta maknanya dengan menggunakan teori Metabahasa Semantik Alami. Metode kualitatif diterapkan dalam penelitian ini. Paradigma penelitian kualitatif berpusat pada pengamatan dari lingkungan sekitar. Data dikumpulkan dari berbagai sumber seperti informan yang merupakan penutur jati bahasa Indonesia dan bahasa Jepang, kamus bahasa Indonesia, corpus bahasa Indonesia dan korpus bahasa Jepang. Penelitian ini menemukan bahwa warna dasar atau primer dalam bahasa Indonesia dan bahasa Jepang ada 5 warna yaitu hitam atau 黒kuro, putih atau 白 shiro, merah atau 赤 aka, biru atau青 ao dan kuning atau黄色kiiro. Penelitian ini juga menemukan bahwa dalam bahasa Indonesia terdapat 61 warna turunan (sekunder) sedangkan dalam bahasa Jepang ditemukan ada 86 warna turunan (sekunder). Penelitian ini juga menunjukkan perbedaan dan kesamaan kategorisasi dan makna warna dalam bahasa Indonesia dan bahasa Jepang. Perbedaan dan kesamaan makna warna dalam bahasa Indonesia dan bahasa Jepang juga dipengaruhi faktor budaya dan alam sekitarnya. Pada dalam bahasa Indonesia, warna putih juga sering diasosiasikan dengan kapas, sedangkan dalam bahasa jepang 白 shiro ‘putih’ juga sering diasosiasikan dengan salju.
Predikat kompleks bahasa Pakpak
Authors: Simanjuntak Dairi Sapta Rindu , Mulyadi Mulyadi
Published: November 2024

Penelitian ini bertujuan untuk mengidentifikasi predikat kompleks bahasa Pakpak (BP) dengan menggunakan pendekatan kualitatif. Data penelitianini adalah kalimat BP. Pengumpulan data dilakukan dengan wawancara kepada lima orang informan penutur BP yang berdomisili di desa. Observasi dilakukan dengan merekam dan mencatat data kalimat BP. Wawancara dilakukan melalui telepon atau chating menggunakan media sosial. Data predikat kompleks yang diperoleh kemudian dianalsis dengan metode agih. Selanjutnya, analisis disajikan dalam diagram pohon menggunakan teoriX-Bar. Hasil penelitian diperoleh menunjukkan bahwa predikat kompleks BP terbagi menjadi tiga tipe, yaitu Tipe I [VIntransitif + VIntransitif], TipeII [VIntransitif + VTransitif], dan Tipe III[VTransitif + VTransitif]. Predikat kompleks BP terbentuk dari dua atau lebih verba melekat secaraberdampingan dan berfungsi sebagai satu predikat tunggal.
Analisis kesalahan berbahasa tataran morfologi dalam tajuk rencana Surat Kabar Riau Pos
Authors: Afuri Resi , Alber Alber
Published: November 2024

Penelitian ini bertujuan mendeskripsikan dan menganalisis kesalahan berbahasa tataran morfologi yang terdapat dalam Tajuk Rencana surat kabar Riau Pos edisi Maret dan April 2024. Penelitian ini menggunakan pendekatan kualitatif dengan metode analisis isi. Sumber data penelitian ini berupa tajuk rencana surat kabar Riau Pos edisi Maret dan April 2024. Data dalam penelitian ini berupa kata yang terdapat kesalahan berbahasa tatatan morfologi dalam Tajuk Rencana surat kabar Riau Pos edisi Maret dan April 2024. Teknik pengumpulan data dalam penelitian ini menggunakan teknik dokumentasi dan catat. Hasil penelitian mengenai analisis kesalahan berbahasa dalam Tajuk Rencana surat kabar Riau Pos edisi Maret dan April 2024 dapat disimpulkan bahwa terdapat kesalahan berbahasa tataran morfologi sebanyak 25 data yang terbagi dalam klasifikasi tataran morfologi: penghilangan afiks 7 data, bunyi yang seharusnya luluh tidak diluluhkan 1 data, penggantian morf 1 data, penyingkatan morf mem-, men-, meng-, meny-, dan menge- 4 data dan penggunaan afiks yang tidak tepat 12 data. Tidak ditemukan dalam klasifikasi: peluluhan bunyi yang seharusnya tidak luluh, penentuan bentuk dasar yang tidak tepat, penempatan afiks yang tidak tepat pada gabungan kata, pengulangan kata majemuk yang tidak tepat. Penelitian ini diharapkan dapat memberikan kontribusi terhadap pemahaman bahasa Indonesia dan juga meningkatkan penggunaan bahasa yang tepat dalam media massa.
Relevansi perlokusi dan pemahaman makna tindak tutur penyandang disabilitas dalam film Dunia Tanpa Suara karya Hanung Bramantyo
Authors: Fibriyanti Veni Masruchah , Suhartono Suhartono , Efendri Yunis
Published: November 2024

Bahasa merupakan alat komunikasi yang bertujuan untuk menyampaikan makna. Sehingga diperlukan adanya interaksi antara penutur dan lawan tutur. Adapun tindak tutur tersebut dapat berbentuk lokusi,i lokusi dan perlokusi. Dalam penelitian ini berfokus pada analisis perlokusi. Penelitian ini bertujuan untuk mendeskripsikan relevansi perlokusi dan pemahaman makna tindak tutur bagi penyandang disabilitas. Penelitian ini menggunakan pendekatan kualitatif deskriptif dengan sumber data berupa tindak tutur tokoh Arissa yang merupakan penyandang tunarungu dan tunawicara berupa gestur maupun bahasa isyarat. Data dikumpulkan dengan metode simak catat. Analisis data melalui tahapan reduksi data,  penyajian data dan penarikan kesimpulan. Dalam penelitian ini ditemukan 24 bahasa isyarat yang mengandung perlokusi. Dalam bentuk perlokusi nonverbal tokoh Arissa yang merupakan penyandang disabilitas tunarungu dan tunawicara. Dari setiap perlokusi tersebut memiliki pemahaman makna yang beragam terdiri dari 10 makna yaitu makna, menolak, mengungkapkan terima kasih, menyukai, mengajak, menjelaskan, menanyakan, meminta,  kebingungan/kecemasan/kekhawatiran,  melawan serta memberi.
Fungsi tindak tutur ekspresif dalam tayangan Kick Andy-Edisi K.H. Abdurahman Wahid di channel youtube Metro TV
Authors: Lavhasa Alfaris Cindy lavhasa , Wijayanti Dedi , Abdi N. Satria
Published: November 2024

A speech in a show has various types and functions. The speakers' speech in Kick Andy show is very diverse and has various functions that are interesting to study because the speech contains the value of critical and deep thinking but still wrapped in humor. This research aims to describe the function of expressive speech acts in the Kick Andy Edition of K.H. Abdurahman Wahid.
This type of research is descriptive qualitative research. The subject of this research is Kick Andy Edition of K.H. Abdurahman Wahid on Metro TV Youtube Chanel. The object of this research is Expressive Speech Actions in Kick Andy Edition of K.H. Abdurahman Wahid on Metro TV Youtube Chanel. This research uses listening method in collecting data. The listening method was conducted with basic techniques in the form of tapping techniques and advanced techniques in the form of free spoken techniques (SBLC).  The data analysis method uses the commensurate method with the basic technique in the form of sorting the determining elements (PUP) technique. The results of this research are as follows: (1) expressive speech act function of criticizing as much as 4 data, (2) expressive speech act function of complaining as much as 4 data, (3) expressive speech act function of blaming as much as 5 data, (4) expressive speech act function of praising as much as 3 data, (5) expressive speech act function of insinuating as much as 1 data, (6) the expressive speech act function of forgiving as much as 3 data, (7) the expressive speech act function of forgiving as much as 1 data, (8) the expressive speech act function of mocking as much as 6 and on the expressive speech act function of gratitude and congratulations are not found in the Kick andy Edition K. H. Abdurahman Wahid so that the amount of data is 27 data.
INVESTIGATION OF THE EFFECTIVENESS OF FIRE RISK EMERGENCY PREPAREDNESS IN HIGH INSTITUTIONS IN THE NIGER DELTA REGION OF NIGERIA
Authors: Ibekwe Nseabasi, Godwin  , Ify Nwaogazie  , Olufemi Adesope  , John Ugbebor
Published: November 2024

The study was carried out to investigate the effectiveness of fire risk emergency preparedness in high institutions in the Niger delta region of Nigeria. Three objectives and two hypotheses were raised to captivate the aim the of the study. The study adopted survey design, and systematic and purposive sampling technique was used to select eight high institutions from eight states in the Niger-Delta while Krejcie and Morgan, table was used to determine sample size of three hundred and twenty-three (382) student, Structured questionnaire, designed using 5-point Likert scale, was used for data collection. Descriptive statistics (percentage and weighted mean score WMS) and ANOVA were used for data analysis. The results of descriptive statistic showed that; the current and existing fire risk assessment methods in the high institution in the Niger-delta is below average (46.80%), the level of awareness and knowledge of students and other stakeholders on fire risk assessment methods among the high institutions in the Niger delta is substantially good (WMS= 3.79 > 3.00) and the level of effectiveness of existing fire risk assessment methods. in the high institution in the study area is substantially good (WMS= 3.91 > 3.00). The ANOVA results used to test the hypotheses revealed that; there is no significant variation in awareness and knowledge levels regarding fire risk assessment methods across the eight states (p-value 0.883 > 0.05 significance level) and there is no significant variation in level of effectiveness of the fire risk assessment methods across the high institutions in the eight states (p-value 0.238 > 0.05 significance level). It was concluded that the effectiveness of fire risk emergency preparedness in high institutions in the Niger delta region of Nigeria is good but required more improvement. It was recommended that the authorities and fire service department in the high institution should improve coordination in emergency response by addressing identified areas for enhancement, such as equipment readiness and communication systems
Impact of Economic Integration on Trade: A Case Study of Pakistan
Authors: Ayaz Abdullah , Akram Muhammad
Published: November 2024

Purpose: This paper tends to examine the impact of economic integration on trade for Pakistan. It studied all trade agreements of Pakistan with partner and non-partner nations. We test whether the trade creation (TC) and trade diversion (TD) effects on trade flows are same across for the members and non-member countries. Also, we have measured comparative advantage and comparative disadvantage.
Design/Methodology/Approach: We have used correctly specified gravity model on the data of imports and exports of Pakistan starting from 1988 till 2020. We have also used Revealed Comparative Advantage (RCA) index in this research work.
Findings: The results revealed from the RCA index shows that Pakistan recorded comparative advantage in most of the commodity group and less comparative disadvantage. Similarly, Pakistan is enhancing trade with partner and non-partner nations in majority of the commodity groups respectively.
Implications/Originality/Value: We may conclude that Pakistan is having trade creation with its partner countries and non-partner countries in most of the agreements.
Impact of External Auditors’ Ethical Behavior on Audit Quality: A Client Perspective
Authors: Sarwar Sania , Hussian Khalid , Shakir Mian M. Niaz , Ali Muhammad Adnan
Published: November 2024

Purpose: This study explores the impact of external auditors' ethical behavior on audit quality, with a particular focus on the perspectives of internal auditors in publicly listed Pakistani companies. It aims to address the gap in literature concerning the interplay between ethical behavior, corporate ethical values, and perceived audit quality.
Design/Methodology/Approach: Using Structural Equation Modeling (SEM), the study examines the direct and indirect effects of external auditors' ethics on audit quality, with corporate ethical values as a moderating factor. Data were collected via a mail survey and Google Forms from auditors in listed Pakistani firms, yielding 232 usable responses (61% response rate). The analysis utilized SPSS and AMOS for reliability, validity, factor analysis, regression, and correlation.
Findings: Results reveal a positive relationship between ethical behavior and perceived audit quality, amplified by strong corporate ethical values. Companies prioritizing ethics reported enhanced audit quality, providing valuable insights for regulators and auditors.
Implications/Originality/Value: This research contributes to the understanding of ethical behavior in audit quality, offering actionable insights for improving ethical standards in audit practices. The findings are pertinent for regulatory bodies, auditors, and policymakers aiming to strengthen financial disclosure integrity in Pakistan
Assessment of parameters of groundwater models using artificial neural networks
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Shatashvili T.A. , Badekin M.Yu. , Benin D.M. , Ivakhnenko N.N. , Konoplin N.A.
Published: November 2024

The paper investigates the possibility of solving the inverse problem using artificial neural networks. To demonstrate the approach, an example is considered consisting of an analytical model of the transfer of pollutants from a point source to a stationary flow field. The model was used to model the behavior of groundwater systems at different values of the dispersion coefficient. Next, a set of controlled multilayer neural networks of direct propagation was trained to evaluate, determine, and select a parameter corresponding to given concentration histories. The results obtained in the work showed satisfactory accuracy of neural network estimates, which confirms the stability of the approach to data analysis in field experiments. When training four artificial neural networks of a controlled, multilayer and direct type, it was found that each of them specialized in a wide range of values. This led to more accurate predictions compared to the case of training a single network over the entire range of values. In addition, the paper shows the ability of a neural network to identify the dispersion parameter at a given concentration under the influence of “noise”. An analysis of the topologies of the applied neural networks has established that the presence of 10 hidden nodes is sufficient to ensure a satisfactory level of calculation accuracy
Innovative technological solutions for engineering and biological structures on agricultural industrial investigation systems
Authors:   Timirâzevskaâ selʹskohozâjstvennaâ akademiâ, Khanov N.V. , Kurbanov S.O. , Сhernikh О.N. , Dudarova F.T.
Published: November 2024

The purpose of the research is to prepare and recommend the implementation of a number of technical solutions for the construction of bioengineered systems for small irrigation systems of surface irrigation along furrows using new environmental techniques of land reclamation. Hydraulic elements and lands of reclamation systems, which are eroded for a number of reasons, must be reliably protected from erosion. As part of the project “Improving the methods of engineering and reclamation of small water bodies of the agro-industrial complex”, bioengineering systems and technologies for protecting not only the coastal areas of small rivers and ponds, under-river water intakes, but also the canals of small surface irrigation systems along furrows were developed and tested under natural conditions using new environmental protection techniques for land reclamation. Biopositive designs are made of local and environmentally friendly man-made materials. Mixed structures contain: gabion mattresses; geomats; metal gratings; geogrids filled with crushed stone; flexible pipelines and other natural and nature-like components. It is noted that the introduction and use of biopositive structures of the developed structures for supplying water for irrigation in reclamation systems of the foothill zones of the North Caucasus Federal District leads to an increase in the economic effect by approximately 2 times and a reduction in the cost of supplied water by more than 40%.