bluuebunny/crossref_metadata_2025 huggingface dataset:
The Analysis of The Decision No. 1706/Pdt.G/2020/PA.Mdn. Based on The Decision No. 93/PUU-X/2012
Authors: Siregar Muhaimin Nur , Siregar Fatahuddin Aziz
Published: March 2024

This research discusses regarding the sharia economic dispute resolution based on akad which usually occures, with analyzed of the Medan Religious Court Decision No. 1706/Pdt.G/2020/PA.Mdn. according the Constitutional Court Decision No. 93/PUU-X/2012 regarding sharia economic dispute resolution based on akad. The type of this research is library research and in the form of normative legal research. The research approach uses statute approach and case approach with theoretical review by pure theory of law and positivism theory of law. The primary legal materials consist of UUD 1945, KUHPerdata, Law No. 21 of 2008 regarding the Sharia Banking, Law No. 3 of 2006 regarding Religious Courts, Law No. 30 of 1999 regarding Arbitration and Alternative Dispute Resolution, Law No. 3 of 2004 regarding the Constitutional Court, Medan Religious Court Decision No. 1706/Pdt.G/2020/PA.Mdn. and Constitutional Court Decision No. 93/PUU-X/2012. The secondary legal materials are books, thesis, and law journals according to the research problems. The colecting datas technique is documentation and the analysis technique uses desciptive analysis. The result of this reseacrh shows that the consideration of the Medan Religious Court Judges’ on the decision No. 1706/Pdt.G/2020/PA.Mdn. who declares that It was not authorized to try the lawsuit based on the explanation of Article 3 of Law No. 3 of 1999 which principally states that the court  is not authorized to try between parties who have been bound in an Arbitration akad and the Constitutional Court Decision No. 93/PUU-X/2012 does not make it has no legal force. Because the two legal standing is separated. Then, by reviewing of the Constitutional Court Decision No. 93/PUU-X/2012 toward the Medan Religious Court Decision No. 1706/Pdt.G/2020/PA.Mdn. regarding the sharia economic dispute resolution based on akad is contradict with law according to the pure theory of law and positivism theory of law. Because the explanation of Article 55 paragraph (2) of Law No. 21 of 2008 that stated sharia economic dispute resolution through arbitration contradict  with  UUD 1945.Sharia Economic Dispute, Dispute Resolution, Akad
Putusan MK Atas Pengujian Formil Undang-Undang Nomor 11 Tahun 2020 Tentang Cipta Kerja
Authors: Yanti Rizka Fitri , Dalimunthe Dermina
Published: March 2024

The problem in this research is related to the Constitutional Court Decision Number 91/PUU-XVIII/2020 on the Review of Law Number 11 of 2020 concerning Job Creation. This type of research is library research through a normative juridical approach. The data sources used are primary and secondary legal materials. Primary legal materials consist of the Constitutional Court Decision Number 91/PUU-XVIII/2020, Law Number 24 of 2003, Law Number 12 of 2011). While secondary legal material includes official documents consisting of scientific articles, books, journals. Data collection techniques in this study were case study and documentation methods. Furthermore, the data analysis technique used in this study is qualitative analysis that is collecting secondary and primary legal materials on the Constitutional Court's decision related to the problem being studied. The results of this study state that the review of Law Number 11 of 2020 concerning Job Creation refers to the provisions of Law Number 12 of 2011 concerning Formation of Legislation. In the process of its formation it did not apply the principles of forming good laws, including not applying the principle of transparency. So that it does not provide space for participation for the public to participate in discussing the law. The consideration of the Constitutional Court judges in composing the decision is the consideration of justice through Conditional Unconstitutional. Then the legal consequences of the formation of the Job Creation Law included cutting severance pay, termination of employment, no maternity leave and miscarriages for women workers.
Dimensi-Dimensi Hukum Pidana Islam Dalam Sanksi Tindak Pidana Begal
Authors: Wahyuni Siska , Gunawan Hendra
Published: March 2024

The problem in this research are the dimensions of islamic criminal law in the criminal act of robbery. The type of research  used is library research using a normatif yuridis approach, namely by using statutory approach. The main data source is the primary data source, namely in article 365 of the criminal code. And secondary data sources are taken from books, legal journal articles, and related documents. Data collection technique or legal materials by identifying data introduction and editing (acurate data checking), This research data analysis technique is by interpreting the data according to the purpose, design and nature of the research. The result of the research obtained in islamic law the sanctions  for legal perpetrators areexile, cross cut hands and peet, santenced to death and exile while in the ciminal code the punishment for legal is only imprisonment and death penaltu, ift the acct does not kill the victim  then the sentence is 9-12 years prison, and the sentence is increased to 15 years if someone dies, that the dimension of islamic criminal law in sanctions for criminal acts of robbery is hudud finger. Therefore, the sanctions for perpetrators off robbery in article 365 of the criminal code are very light when compared to the sanctions for perpetrators of robberies in islmic law.
Fasilitator Tidak Bersertifikat Dalam Kursus Pranikah Islam Sebagai Penyebab Perceraian Di Indonesia
Authors: Sobhan Sobhan
Published: March 2024

Kursus Pranikah yang diprogram dan dilaksanakan oleh Kementerian Agama Republik Indonesia tidak berpengaruh kepada ketahanan keluarga di IndonesiA.Didasarkan pada data yang ada pada Badan Pusat Statistik dari tahun 2017 sampai 2021 terdapat lonjakan angka perceraian yang signifikaN. Artikel ini menjelaskan bahwa negara sudah menyiapkan semua perangkat yang lengkap, mulai dari regulasi sebagai payung hukum penyelenggaraan kursus, penyelenggara, sarana, biaya sertifikasi sampai kepada materi dan narasumber. Tujuannya ialah agar rumah tangga yang sudah dibangun bisa bertahan untuk selamanya, tidak digerogoti pertikaian dan tidak pula diserang oleh perpecahan. Data penelitian dikumpulkan melalui wawancara mendalam terhadap satu orang hakim Pengadilan Agama Padang Kelas 1-A dan empat orang Penghulu yang bertugas di Kantor Urusan Agama Padang Sumatera Barat. Temuan penelitian ini menunjukkan bahwa penyelenggaraan Kursus Perkawinan Pranikah belum terlaksana sesuai dengan yang digariskan dalam pedoman dan petunjuk pelaksanaannya. Temuan ini dapat berimplikasi pada perlunya menata ulang penyelenggaraan Kursus Perkawinan Pranikah, terutama pada bagian perangkat yang terkait langsung dalam pelaksanaannya terutama fasilitator yang sudah harus tersertifikasi sebelum diterjunkan ke lapangan dan sarana prasarana yang dibutuhkan secara lengkap.
Increasing Student Learning Motivation through of the Dick and Carey Model in Islamic Religious Education
Authors: Nugraha Mulyawan Safwandy , Purnasari Martina , Dedih Ujang
Published: March 2024

This research focuses on addressing the persistent challenge of motivating students in their engagement with Islamic Religious Education (PAI) materials. Despite the overarching goal of instilling virtue, there remains a recurring issue of insufficient motivation among students when it comes to PAI content. In response, this study investigates the potential effectiveness of applying the Dick and Carey instructional model within the context of GIS Prima Insani Elementary School. Employing a qualitative case study methodology, the research highlights the Dick and Carey model's systematic and organized approach. This instructional model emphasizes transparent steps that contribute to the clarity of learning outcomes, encouraging students to apply acquired knowledge in their daily lives—aligned with the broader objective of Islamic religious education. The findings suggest that the Dick and Carey model is well-suited for educational settings, offering a clear direction for both educators and students and fostering a sense of recognition and support. The structured nature of the model contributes to heightened commitment among students, ultimately enhancing motivation and facilitating optimal learning outcomes. In conclusion, the study underscores the significance of implementing effective instructional models, particularly the Dick and Carey approach, in Islamic religious education. By nurturing motivation and aligning with established standards, this model emerges as a valuable tool for educators, contributing to an overall enhanced educational experience. The findings emphasize the importance of adopting innovative approaches to address challenges in Islamic religious education, paving the way for future research and improvements in pedagogical practices
Dakwah Via Youtube? Evolving Dynamics of Religious Communication in Aceh Islamic Society
Authors: Meriza Iin , Febriani Asra , Tisa Mutia , Nurdin Muhammad Riza
Published: March 2024

The progress of information technology is currently very rapid. Any information can be received directly by the public in a matter of seconds via various social media. The YouTube platform is one of the social media that is popular with the public and is a good opportunity for da'wah activities. Da'i in Aceh took part in utilizing the YouTube platform as a medium for da'wah. This research aims to find out the information related to the use of the YouTube platform as a medium for da'wah in Aceh and knowing the character of da'wah by using the YouTube platform in Aceh. This research is field research using a qualitative approach. In determining research subjects, the author used purposive sampling so that researchers could gather information from users of the YouTube platform as a medium for preaching, especially YouTube channels that already exist among the public. The research results show that the aim of using the YouTube platform as a da'wah media in Aceh is to contribute to knowledge in institutions, unite alumni/organizations, store da'wah documentation, narrow down entertainment content, and expand the da'wah network. This article aims to explore the use of YouTube as a medium for da'wah in the post-modern era in Aceh, where da'wah is experiencing very rapid development. Furthermore, in this article the author exposes YouTube preaching content that can be accessed by various groups.
USE OF INTERACTIVE MULTIMEDIA IN INCREASING MOTIVATION FOR LEARNING SCIENCE AT PRIMARY SCHOOL
Authors: Nasir Muhammad Fikri Abdun , Fatonah Siti
Published: March 2024

This study aims to describe the implementation of interactive multimedia animation videos in increasing the learning motivation of grade 1 B students in the subject of Civics Education Theme 5, as well as the positive impacts that arise after the application of interactive multimedia animation videos in increasing the learning motivation of grade 1 B students at MI Al-Ishlah Jepara. The type of research used is field research with a qualitative approach. This study uses data collection techniques through the observation method, interview method with 6 subjects namely the principal, science subject teacher, curriculum teacher, and 3 students in grade 1 B, and the documentation method. The data analysis method used is through observation, interviews, and documentation. Test the validity of the data from this study using triangulation techniques with data analysis in the form of data collection, data reduction, data presentation, as well as drawing conclusions and verification. The results of this study can show that: 1) The implementation of interactive multimedia animation videos can increase students' learning motivation in several ways, namely the teacher explains the material using animated multimedia videos, students listen and pay attention, the teacher gives questions to students in turn as a form of for strengthening the level of understanding of students, the teacher provides evaluations in the form of worksheets to students in order to find out how successful students are in learning seen through the learning outcomes obtained. Thus, the application of interactive multimedia video animation is very appropriate to be used to increase students' learning motivation. 2) the positive impact when the application of interactive multimedia video animation takes place is that students can be enthusiastic in participating in lessons, they also look active, focused, responsive, and enthusiastic in the learning process and are able to understand the material well, so that the learning outcomes they get are maximized because they are motivated to learn.
FATHER ROLE IN EDUCATION CHILDREN ACCORDING TO THE PERSPECTIVE OF ISLAMIC EDUCATION
Authors: Irmawati Irmawati
Published: March 2024

The phenomenon that is found today, culturally among the people still views the father's role as being responsible only as a breadwinner. So that the father's time and thoughts are focused and eroded to make a living, and run out of opportunities in educating children. Children do not get the affection and touch of education from the father figure, which has an impact on children's behavior and causes a moral crisis in children. While the role of fathers in educating children is very important and related to the growth and development of children. In the Al-Quran, stories of the role of successful fathers in educating their children are found. Like the story of Lukmanul Halim, the story of Prophet Ibrahim AS, Prophet Zakaria US and the story of Prophet Ya'kub US. The formulation of the problem in this study is what is the role of the father in educating children according to the perspective of Islamic education? Described objectively and systematically. This research succeeded in finding several concepts of the father's role in educating children's spiritual spiritual education according to the perspective of Islam, which can be revealed, among others: by instilling faith, introducing and instilling halal and haram laws, educating children to establish prayer, educating children to love Rasulullah SAW, and getting used to children to read the Koran. Some concepts of the father's role in educating children's physical education according to the perspective of Islamic education are: by getting children to exercise, providing halal and thoyyib food, maintaining children's health and seeking treatment and providing a safe and proper place to live. Some of the concepts of the father's role in educating children's intellect according to the perspective of Islamic education are: by instilling a love of knowledge, guiding, facilitating children to memorize the Qur'an and Hadith, selecting good schools and teachers, providing a home library, and directing children on their talents and Some concepts of the father's role in socially educating children according to the perspective of Islamic education are: Get to know the child's personality, instill basic psychological principles (piety, brotherhood, compassion and forgiveness), create a comfortable atmosphere at home, and supervise the environment and playmate.
Optimalisasi Sumber Daya Manusia dalam Pengelolaan Daerah Aliran Sungai (DAS) Melalui Sekolah Lapang Konservasi
Authors: Ahdi Muhamad
Published: March 2024

AbstrakPermasalahan lingkungan hidup sampai saat ini adalah suatu problem yang belum dapat diatasi secara tuntas, yang mana permasalahan muncul semakin berkembang dalam kuantitasnya dan beragam pula macamnya. Kerusakan yang disebabkan karena ulah tangan manusia sebagai aktor utamanya. Padahal sesuai dengan aturannya manusia tidak dianjurkan untuk mengeksploitasi sumber daya alam secara berlebihan yang mana nantinya dikhawatirkan akan terjadi kerusakan serta kepunahan sumber daya alam, sehingga tidak dapat diwariskan untuk generasi mendatang. Untuk itu manusia diwajibkan menjadi pelaku aktif dalam mengolah lingkungan dan melestarikannya. Penelitian ini bertujuan untuk mengurai bagaimana tindakan yang dibangun masyarakat Desa Mlandi dalam menanggapi persoalan kerusakan lingkungan. Tindakan yang diusung yakni pembentukan sekolah lapang konservasi sebagai wadah mengoptimalkan kemampuan sumber daya manusia. Metode penelitian ini menggunakan kualitatif deskriptif dengan data yang diperoleh dari studi observasi, wawancara mendalam dan dokumentasi dan analisis teori kekuatan. Hasil penelitian ini menunjukkan pola kegiatan gerakan sadar lingkungan dalam pembelajaran sekolah advokasi alam dengan tindakannya dengan konservasi vegetasi dan sipil teknis. Pendampingan ini telah memberikan dampak berupa berkurangnya kejadian degradasi tanah, tanah longsor dan banjir ketika hujan. Dari segi kemajuan telah memberikan motivasi, dorongan semangat untuk berperan aktif dan mendapatkan pengetahuan baru untuk lebih sadar terhadap lingkungan terlebih bisa berdampak dalam peningkatan ekonomi melalui produksi hasil kopi. Serta memiliki komitmen dan tanggung jawab untuk tetap menjaga dan melestarikan lingkungan alam sekitar terkhusus di Desa Mlandi.Kata kunci: Kerusakan Lingkungan, Optimalisasi SDM, Sekolah Lapang Konservasi
Analisis Penyebab Ketidakberlanjutan Program Pelatihan (Studi Kasus Pelatihan Bakso Desa Bumirejo Kecamatan Puring Kabupaten Kebumen)
Authors: Nurjannah Aola
Published: March 2024

Setiap tahunnya pemerintah wajib menganggarkan program pengembangan sumberdaya manusia sesuai dengan usulan pada musrembangdes. Dalam program pengembangan sumber daya manusia ini, Desa Bumirejo memilih pelatihan sebagai dasar dari upaya mengembangkan masyarakat. Terutama meningkatkan produktifitas ibu rumah tangga yang diharapkan mampuu dimanfaatkan sehingga dapat meningkatkakn perekonomian keluarga dan mencapai kesejahteraan masyarakat. Akan tetapi faktanya pelatihan tersebut ternyata tidak berkelanjutan atau tidak ada followup setelahnya. Penelitian ini bertujuan untuk menggali lebih dalam penyebab ketidakberlanjutanya program pelatihan sebagai bagian dari evaluasi program. Setelah diketahui dan dipahami kemudian akan kembali dibenahi agar bisa kembali berjalan untuk kemaslahatan bersama. Metode yang digunakan dalam penelitian ini adalah kualitatif deskriptif melalui pendekatan studi kasus di desa Bumirejo, Kecamatan Puring, Kabupaten Kebumen. Data diperoleh melalui wawancara kepada, pemerintah, tokoh, dan warga masyarakat. peneliti juga melakukan observasi dan dokumentasi di Desa Bumirejo. Hasil penelitian memnunjukan ada 3 penyebab untama ketidakberlanjutan program pelatihan yaitu partisipasi masyarakat, pengelolaan finansial yang kurang baik. dan tidak bermitra. Harapannya penelitian ini bisa menjadi rekomendasi begai pemerintahan desa untuk mengatasi kendala kendala yang ada sebagi bahan pembelajaran untuk memperbaiki program atau membuat program yang lebih baik.
اللغة وعلاقتها بالتدين
Authors: Lubis Sufrin Efendi
Published: March 2024

تجريدإن اللغة هي وسيلة التواصل بين البشر، فباللغة يعبر الإنسان عما يحبه وما يكره، ومن خلال اللغة يستطيع الإنسان أيضاً مدح الآخرين والتقليل من شأنهم. وهذا دليل واضح على أهمية اللغة للإنسان، لأنه باللغة يحترم الإنسان أو يهان، وبالتالي هناك علاقة بين اللغة، وخاصة لغة اللسان والتدين. وكان هدف البحث هنا يدور حول التعرف على اللغة خاصو بالتي يتم التعبير بها بالكلمات، ولذا ستكون الحديث بشكل مطول عن اللغة المنطوقة, والمارد باللغة هنا التي يستخدمها الشخص للتعبير عما يريد. وأما سؤال البحث المقترح في البحث هو هل هناك علاقة بين ما يقال من خلال الكلام وجودة التدين. وكان نوع البحث المستخدم هو البحث المكتبي، حيث تعتبر الكتب أحد المصادر الرئيسية، مع عدة مصادر إضافية أخرى مثل كمقالات علمية ومنشورات على الإنترنت وغيرها حسب احتياجات البحث. وبعد إجراء عملية البحث تبين أن هناك علاقة متبادلة بين اللغة والتدين، فاللغة هي السبب والتدين هو النتيجة. وكلما حسنت اللغة كان التدين أفضل، ولكن ليس هذا هو المقياس الوحيد لمعرفة التدين، بل يمكن أن يكون الإنسان ذو لسان لين، وحسن كلام، فيلعنه الله على نفاقه وحسده.الكلمات المفتاحية: اللغة , العلاقة و التدينAbstrackLanguage is a means of communication between humans, with language, a person expresses what he likes and dislikes, and through language a person can also praise and belittle other people. This is clear evidence of the importance of language to a person, because with language a person is respected or insulted, therefore there is a relationship between language, especially spoken language and religiosity. The aim of the research here revolves around getting to know language specifically which is spoken in words, because the researcher will talk at length about spoken language and the language a person uses to express what they want. The research question must be: "Is there a relationship between what is said through speech and the quality of religiosity?" The type of research used is library research, where books are considered as one of the main sources, with several other additional sources such as scientific articles, publications on the internet, etc. others, according to research needs. After carrying out the research process, it was discovered that there was a reciprocal relationship between language and religiosity, language being the cause and religiosity being the result. The better the language, the better the religiosity, but that is not the only benchmark for knowing religiosity, but it could be that someone has a soft tongue and good words, while Allah curses him for his hypocrisy and envy.Key words: language, relationship and religiosity
Inhibition of Xanthine Oxidase by Pyrazolone Derivatives Bearing a 4-(Furan-2-yl)benzoic Acid Moiety
Authors: Beiko Alona V. , Kobzar Oleksandr L. , Kachaeva Maryna V. , Pilyo Stepan G. , Tanchuk Vsevolod Yu. , Vovk Andriy I.
Published: March 2024

The pyrazolone-based 4-(furan-2-yl)benzoic acids have been synthesized and studied as xanthine oxidase inhibitors. This enzyme is one of the therapeutic targets for the treatment of hyperuricemia and related diseases. The compounds studied have found to exhibit low micromolar IC50 values relative to the enzyme in vitro, depending on substituents in position 3 of the pyrazolone ring. However, the inhibitory effects observed are reduced in the presence of bovine serum albumin or Tween-80. Among the pyrazolone derivatives synthesized, 4-(5-((3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)methyl)furan-2-yl)benzoic acid has been found to be the most potent inhibitor of xanthine oxidase. Kinetic results have shown that this compound is a mixed-type inhibitor with higher affinity to the free enzyme than to the enzyme-substrate complex. The results of the molecular docking and molecular dynamics show that the carboxylic group of the inhibitor can form a salt bridge with Arg880 and a hydrogen bond with Thr1010. These interactions can be key factors in the enzyme-inhibitor complex stabilization.
Participação popular nos hospitais universitários federais: uma análise do princípio constitucional no sistema único de saúde (SUS) e sua aplicação na empresa brasileira de serviços hospitalares (EBSERH)
Authors: Soares Mesquita Lucas Isaac
Published: March 2024

O trabalho pretende apresentar os parâmetros da participação popular no Sistema Único de Saúde (SUS) e investigar a observância destes na Empresa Brasileira de Serviços Hospitalares (EBSERH), responsável pela gestão de 40 dos 50 hospitais universitários do país.Demonstra os princípios e diretrizes que erguem a saúde pública, enfocando na democracia sanitária como fundamental à efetividade deste direito social no Brasil, seja em sua acepção institucionalizada ou não institucionalizada, atentando ao papel funcional dos Conselhos e Conferências de saúde para a formulação, execução e fiscalização de políticas públicas. Em análise, os principais fundamentos que motivaram a criação da EBSERH após acórdãos do Tribunal de Contas da União (TCU) e a vinculação ao Programa de Reestruturação dos Hospitais Universitários Federais (REHUF), questionando abertura à participação popular em sua estrutura interna de órgãos de administração, fiscalização, comitês e comissões. Constata-se uma redução e não observância aos parâmetros de controle social nas estruturas da EBSERH, dificultando a legitimidade popular nas tomadas de decisão e na execução de ações e serviços de saúde pertinentes à maior rede de hospitais do sistema público do país.
FRENECTOMIA LINGUAL COM LASER DE DIODO DE ALTA POTÊNCIA: RELATO DE CASO
Authors: Raianne Santos Sa Joyce , Peixoto Maria Juliana Alcantara de Sousa , Araújo Ozanna Soares Medeiros de , Jales Agatha Sabrina dos Santos , Gonçalves Maria Lívia Vitória Alves , Maia Clara Martins , Limeira Wâne Marquesa Jordão , Sousa João Nilton Lopes de
Published: March 2024

Introdução: A laserterapia de alta potência tem estabelecido proporções satisfatórias na odontologia e se tornando a primeira opção de conduta cirúrgica para procedimentos, trazendo qualidade de vida aos pacientes e praticidade aos Cirurgiões. Objetivo: Relatar caso clínico de frenectomia lingual com uso do laser de diodo de alta potência ressaltando os benefícios da conduta. Relato de caso: Paciente sexo feminino, leucoderma, sem alterações sistêmicas, chega à Clínica Escola de Odontologia da Universidade Federal de Campina Grande, com queixa principal de alterações na sua fonologia. No exame intraoral observou-se dificuldade de movimentação lingual e em formato de coração devido a inserção fibrosa do freio, sendo observado a Anquiloglossia. Após explicações da alteração, do tratamento, e assinatura do Termo de Consentimento, foi iniciado a cirurgia: antissepsia, anestesia com vasoconstrictor, e em modo contínuo utilizou-se o laser de diodo de alta potência (TW Surgical- MMO®) configurado em 2W de potência, fibra 600µm, no comprimento de onda infravermelho, de modo que as fibras fossem separadas uniformemente e promovesse mobilidade imediata da língua, por fim realizou-se uma sutura em ponto simples com fio reabsorvível. Para o pós-operatório foi prescrito Dipirona em caso de dor, e estabelecido o acompanhamento. No retorno de 7 dias observou-se cicatrização normal e não ingestão do medicamento, em 30 dias foi visto a completa cicatrização e mobilidade sem desconforto, além de relato da paciente de melhoria na condição de relacionamentos sociais, autoestima e deglutição. Conclusão: O resultado apresentado neste artigo ratifica a benefício da escolha do laser em comparação ao convencional, demonstrando que não há sangramento no trans e pós cirúrgico, além de favorecer o processo de reparação tecidual, da redução do tempo cirúrgico, aumento do conforto, e diminuição de uso de medicamento, desta forma associando o laser cirúrgico a melhoria da qualidade de vida.
Technical Details of a Novel Surgical Procedure for Construction of the Modified Blalock–Taussig Shunt (UKC’s Modification): A Video Presentation
Authors: Chowdhury Ujjwal K. , George Niwin , Kanmaniyan B. , Mishra Sundeep , Chittimuri Chaitanya , Kapoor Poonam Malhotra , Goja Sikha , Pandey Niraj Nirmal
Published: March 2024

We describe herein the surgical technique on a 2.5-years-old male child weighing 10 kilograms diagnosed with a functionally univentricular heart, disproportionately small right subclavian artery, and hypoplastic pulmonary arteries (Mc Goon’s ratio of less than 1.0).5 We interposed a short segment of polytetrafluoroethylene graft between the right brachiocephalic artery and the intrapericardial portion of the right pulmonary artery closest to the bifurcation of the pulmonary trunk on the right side.
Learning Strategy Oriented to High Order Thinking Skills (HOTS)
Authors: Kurniawan Andriyanto , Wahyuni Sri , Sugiyatmi Anik , Pratiwi Veronika Unun , Nugrahani Farida
Published: March 2024

The aim of the research is to describe High Order Thinking Skills-oriented Indonesian language learning strategies in learning at school. The research method used is qualitative. The approach in this research is descriptive qualitative. The data used is in the form of various learning strategies in the independent curriculum related to the implementation of Indonesian language learning activities in schools. Data sources were obtained through scientific articles and journals which theoretically have been proven to be relevant regarding the relevance of using HOTS (High Order Thinking Skill) oriented Indonesian language learning strategies. Data collection techniques use library research. Data analysis techniques use reading, listening and taking notes. Data validity techniques through theoretical triangulation. The research results show that (1) Indonesian language learning strategies are oriented towards high level thinking including project based learning, problem based learning, discovery learning, and inquiry. (2) learning Indonesian using the project based learning model will make students active, creative and innovative in producing learning products. (3) The use of the problem based learning model in Indonesian language learning makes students trained to formulate and solve problems carefully so that independent activities and constructive thinking can be mastered by students. The use of discovery learning and inquiry models makes students more skilled in critical thinking to find new ideas and understanding in learning Indonesian. The criteria for learning strategies oriented at a high level of thinking are based on the 4Cs as characteristics of 21st century learning.
Towards the Industrial Implementation of Mn-based Catalyst for the Hydrogenation of Ketones and Carboxylic Esters
Authors: Link Achim , Furer Patrick , Clarke Matthew L. , Müller Marc
Published: March 2024

There is a constant pressure in industry to move away from platinum group metals (PGM) and achieve more environmentally friendly and sustainable production processes in the future. Recently developed Mn-based catalysts offer an interesting opportunity to complement established catalysts based on Ru. In this article, recent achievements in the field are highlighted and recent achievements in the collaboration of Solvias AG with the group of Prof. M. Clarke towards the implementation of these catalysts on industrial scale are outlined.
Enhanced Mechanistic Understanding Through the Detection of Radical Intermediates in Organic Reactions
Authors: Ocaña Ivan , Williams Peter J. H. , Donald James , Griffin Neil , Hodges George , Rickard Andrew R. , Chechik Victor
Published: March 2024

Two applications of a radical trap based on a homolytic substitution reaction (SH2') are presented for the trapping of short-lived radical intermediates in organic reactions. The first example is a photochemical cyanomethylation catalyzed by a Ru complex. Two intermediate radicals in the radical chain propagation have been trapped and detected using mass spectrometry (MS), along with the starting materials, products and catalyst degradation fragments. Although qualitative, these results helped to elucidate the reaction mechanism. In the second example, the trapping method was applied to study the radical initiation catalyzed by a triethylboronoxygen mixture. In this case, the concentration of trapped radicals was sufficiently high to enable their detection by nuclear magnetic resonance (NMR). Quantitative measurements made it possible to characterize the radical flux in the system under different reaction conditions (including variations of solvent, temperature and concentration) where modelling was complicated by chain reactions and heterogeneous mass transfer.
Industrial Distillation Aspects of Diketene
Authors: Biçer Mehmet Ogün , Von Harbou Erik , Klein Andreas , Lorenz Hilke-Marie , Taeschler Christoph
Published: March 2024

Large-scale distillation is a challenge in many respects. Particularly difficult is the purification by distillation of a compound with limited thermal stability. This article describes various aspects of these difficulties with some possible solutions. Special emphasis is placed on the collaboration of different disciplines to find pragmatic solutions to these challenges. The purification of diketene in quantities of several 1000 ta–1 is an excellent example to illustrate the different requirements. Although the distillation of diketene has been carried out by several companies for many years, there are still some aspects that deserve special attention.
A Descriptive Study of the Students' Problems in English Reading Comprehension of X grade at SMAS AMKUR Sungai Pinyuh in the Academic year 2021/2022
Authors: Aditya Denuk Ayu , Antonia Tia
Published: March 2024

This study investigates the problem of student English reading in the Senior High School of SMAS AMKUR Sungai Pinyuh in terms of types of material, reading tasks, and cognitive level of reading tasks. The participant of this study consists of 23 students of grade X Social Studies. The researchers used descriptive qualitative research to develop the material in teaching reading, especially for English subjects. Not only for the texts, vocabulary, and the information but also to build students’ critical thinking in reading comprehension. The book used as the instrument is Bahasa Inggris SMA/MA/SMK/MAK Kelas X Edisi Revisi 2017 published by Pusat Kurikulum dan Perbukuan, Balitbang, Kemendikbud. The findings based on the teacher’s observation from the students showed that some texts are too long and most of the time the readers do not suitable to the local contexts, the text used unfamiliar words to the students, and the books do not provide the list of vocabularies, used direct information to the answers of the questions after reading the text. Based on the research findings, the recommendation to improve students' reading comprehension is that the teacher needs to be more selective to know that the material is suitable for the students.
Assessment of Two Mass Screening Campaigns for Pre-Cancerous and Cancerous Lesions of the Uterine Cervix using Colposcopy
Authors:   Department of Gynaecology-Obstetrics, Institute of Social Hygiene Hospital of Dakar, Senegal, MM Niang , F Samb ,   Department of Gynaecology-Obstetrics, Institute of Social Hygiene Hospital of Dakar, Senegal, CT Cisse ,   Department of Gynaecology-Obstetrics, Institute of Social Hygiene Hospital of Dakar, Senegal
Published: March 2024

Objectives: Study the epidemiological profile of patients seen for colposcopy, specify the indications for colposcopy, describe the lesions encountered and their treatment and determine the factors associated with cervical lesions. Material and methods: This was a cross-sectional study conducted during October 2021. It concerned 2 “fairground” campaigns for systematic mass screening of pre-cancerous and cancerous lesions of the cervix at the Institute of social Hygiene in Dakar and at the Inter-Army Medical Center in Thiès. The parameters studied were the epidemiological data, the results of the colposcopic examination and histology. Data analysis was performed with Excel 2010 and Epi info 7.2. softwares. Results: During the two mass screening campaigns, we performed 50 colposcopic examinations. The epidemiological profile was a woman aged 45 on average, married (86%), multiparous (54%), in period of genital activity (54%) with a first sexual intercourse made on average at 22 years old. All the patients had benefited from a visual inspection with acetic acid and lugol. Visual inspection with acetic acid and lugol showed 15 positive VIA (30%), 14 positive VIL (28%) and 21 cases of positive VIA and VIL (42%). Colposcopy was satisfactory in most patients (78%). It found 36% atypical grade 2 transformation, 10% atypical grade 1 transformation, 2% association of atypical grade 1 and 2 transformation and 10% viral colpitis. We also recorded 18% of normal colposcopy. In our series, the majority of patients in whom the VIA and VIL tests were positive presented at colposcopy either an atypical grade 2 transformation lesion (72.2%) or a ATG 1+2 lesion (5.5%). This rate was only 14.3% in those who only had the positive IVA test and 50% in the case of positive VIL. A biopsy under colposcopy was performed in 20 patients (40%). Of these, only 5 (25%) had brought back the results. It was a CIN 2 and 4 normal results. A multivariate analysis allowed us to find that TAG 2 lesions were more frequent in patients aged 45 and over (60%) (p=0.46), primiparous (100%) (p=0.62), those who had had first sexual intercourse before the age of 20 (69.2%) (p=0.39) and who had not used a contraceptive (88.9%) (p=0.13). Conclusion: Mass screening campaigns constitute in our developing countries an opportunity to diagnose and treat pre-cancerous and cancerous lesions of the cervix. However, it will be necessary to sensitize the patients screened for a better adhesion to the follow-up.
The rs2304256, a Non-Synonymous Polymorphism in Tyrosine Kinase 2 Gene is Associated with the Risk of Endometriosis
Authors:   Department of Biochemistry, Osmania University, India, Veena KV , Latha Manolla Madhavi ,   Department of Biochemistry, Osmania University, India, Deenadayal Mamata ,   Infertility Institute and Research Centre (IIRC), India, Shivaji Sisinthy ,   Centre for Cellular and Molecular Biology (CCMB), India, Bhanoori Manjula ,   Department of Biochemistry, Osmania University, India
Published: March 2024

The objective of the study was to investigate whether the TYK2 gene influences the risk of developing endometriosis in South Indian women. The non-synonymous SNP, rs2304256, in exon8 of the TYK2 gene was tested for association in a case–control study of 150 affected women and 150 women with no evidence of disease. The genotype frequencies of the polymorphism were compared using polymerase chain reaction and restriction fragment length polymorphism. Immunohistochemistry was used to analyze the distribution and expression of TYK2 in the endometrium of women with and without endometriosis. According to codominant, dominant, and recessive genotype models, statistically significant differences were observed in the genotype distribution and allele frequency (P=0.0432) between the cases and controls. The distribution and expression of TYK2 did not vary in the endometrium of cases and controls. In the present study, we could establish an association between the TYK2 rs2304256 non-synonymous polymorphism with the risk of endometriosis in South Indian women, indicating that this polymorphism may lead to significant disease susceptibility.
Nanobots for Medicinal Applications
Authors:   School of Chemical Sciences, NISER, Odisha, 752050, India, Parida Smrutimedha , Bari Anil Ramdas ,   Department of Physics, Arts, Commerce and Science College, Bodwad, Maharashtra, 425310, India
Published: March 2024

The applications of nanotechnology have increased exponentially in the field of medicinal chemistry with the implementations of nanorobotics. Nanobots provide one of the most promising areas of nanotechnology spreading its roots to applications in various fields including medical imaging, drug delivery and even in the development of Nanobots have the advantages of small size, low weight, large thrust-to-weight ratio, high flexibility, and high sensitivity. The applications of nanobots are varied and are being explored in various fields. The aim of this review is to offer an overview to the emerging field of nanorobotics within medicinal chemistry and their applications for diagnosis, treatment and prevention of various diseases. It provides a comprehensive overview of the development of nanobots. The key components of the robots and the types of nanobots are discussed separately. The review also focuses on the disadvantages and the challenges in the development of nanobots for their specific causes. And finally, the efforts and measures that can bring us steps closer to the dream of catching up with our fantasies of developing tiny robots that could roam about inside our bodies, delivering drugs with unprecedented precision, and hunting down and destroying infected cells and most importantly science fiction becoming scientific fact are discussed.
Nano-Warriors Against Cancer: Who Won?
Authors:   Department of Medicine, Shifa College of Medicine Islamabad, Pakistan, Mehmood Asim
Published: March 2024

One of nanotechnology's most rapidly expanding fields, nanomedicine has the potential to revolutionize healthcare and medicine by creating ground-breaking new diagnostic and therapeutic instruments. According to the definition of nanotechnology, it is the deliberate design, characterization, manufacture, and uses of materials, structures, devices, and systems by regulating their size and form in the nanoscale range (1 to 100 nm). Currently, nanomaterials are being developed to help molecules pass past biological barriers, to access molecules, to mediate interactions between molecules, and to detect molecular changes in a sensitive, highly efficient manner [1].
Intra-Articular Osteoid Osteoma of the Hip: An Observation and the Review of the Literature
Authors:   Department of Trauma and Orthopedic Surgery, Ibn Sina University Hospital, Faculty of Medicine, Mohamed V University of Rabat, Rabat, Morocco, Amine El Maqrout , Abdelaziz Ghannam ,   Department of Trauma and Orthopedic Surgery, Ibn Sina University Hospital, Faculty of Medicine, Mohamed V University of Rabat, Rabat, Morocco, Jalal Mekkaoui ,   Department of Trauma and Orthopedic Surgery, Ibn Sina University Hospital, Faculty of Medicine, Mohamed V University of Rabat, Rabat, Morocco, Boufettal Moncef ,   Department of Anatomy, Faculty of Medicine, Mohamed V University of Rabat, Rabat, Morocco, Allah Bassir Reda ,   Department of Anatomy, Faculty of Medicine, Mohamed V University of Rabat, Rabat, Morocco, Mohammed Kharmaz ,   Department of Trauma and Orthopedic Surgery, Ibn Sina University Hospital, Faculty of Medicine, Mohamed V University of Rabat, Rabat, Morocco, Moulay Omar Lamrani ,   Department of Trauma and Orthopedic Surgery, Ibn Sina University Hospital, Faculty of Medicine, Mohamed V University of Rabat, Rabat, Morocco, Saleh Berrada Mohammed ,   Department of Trauma and Orthopedic Surgery, Ibn Sina University Hospital, Faculty of Medicine, Mohamed V University of Rabat, Rabat, Morocco
Published: March 2024

Osteoid osteoma is a common benign bone tumor that affects young adults and has a typical clinical and radiographic presentation in long bones. However, when it appears in unusual intra-articular locations, the clinical symptomatology is then atypical and can lead to misdiagnosis constituting a diagnostic challenge for clinicians and causing delay in management. We present the case of a girl of 16 years with an osteoma osteoid intra-articular right hip involving the femoral head. This unusual location was the cause of unexplained pain and a delay in diagnosis of 20 months after the onset of symptoms, as the initial Magnetic Resonance Imaging (MRI) examination could not identify the lesion. The tomodensitometry is in this indication the most specific examination which made it possible to evoke the diagnosis of osteoid osteoma. Once the diagnosis is made, given the complexity of the location, it makes it difficult to access radio-guided techniques. The open surgical excision allowed healing with complete disappearance of pain. After complete surgical excision of the tumor, histopathological examination confirmed the final diagnosis of intra-articular osteoid osteoma. No recurrence was observed.
Obturator Dislocation of the Hip in An Athlete: A Rare Injury
Authors:   Department of Orthopedic Surgery, Ibn Sina Hospital, Faculty of Medicine and Pharmacy of Rabat, University Mohamed V, Rabat, Morocco, Rida El Galiou Mohamed
Published: March 2024

Hip Dislocation, particularly the Obturator Variety, is a rare entity, especially in sport settings. It requires reduction within a timeframe of less than 6 hours, performed by a qualified surgeon who is aware of the risk of complications. We report a case of obturator dislocation (anteroinferior) in a 56-year-old patient who is a cycling enthusiast.
Amniotic Membrane Transplantation for Paracentral Corneal Perforations
Authors:   Shenzhen Eye Hospital, Jinan University, Shenzhen Eye Institute, Shenzhen 518040, China, P Guo , JJ Su ,   Shenzhen Eye Hospital, Jinan University, Shenzhen Eye Institute, Shenzhen 518040, China, BT Lin ,   Shenzhen Eye Hospital, Jinan University, Shenzhen Eye Institute, Shenzhen 518040, China, Y Zhang ,   BioTissue (TissueTech, Inc.), 7235 Corporate Center, USA, YT Zhu ,   BioTissue (TissueTech, Inc.), 7235 Corporate Center, USA
Published: March 2024

Objective: To report the clinical efficacy of Amniotic Membrane Transplantation (AMT) for paracentral perforations caused by Blepharokeratoconjunctivitis (BKC). Methods: A retrospective review was performed on consecutive patients that had paracentral corneal perforations caused by BKC and were subsequently treated with AMT between October 2019 and September 2021. Visual acuity (BCVA), anterior chamber depth, angle opening, corneal thickness and number of Demodex mites were examined before and after the operation. Results: Eleven eyes of 11 patients (2 males, 9 females, aged 11- 22 years old) with BKC were included in the analysis. Three months after AMT, BCVA significantly improved from 1.14 ± 0.8 at baseline to 0.35 ± 0.2 (p=0.004) and the proportion of patients with mite infestation decreased from 7 cases (64%) to 2 cases (18%). OCT confirmed the corneal perforations healed with normal corneal thickness and formation of anterior chamber with normal angle opening. During the follow up duration of 6-17 months, no recurrence or complications were noted. Conclusion: This case series suggests AMT can restore vision and corneal thickness in patients with aseptic corneal perforations caused by BKC.
Role of Topography in Cataract Surgery Planning: Narrative Review
Authors:   Deparment of Neuroscience Biomedicine and Movements, University Hospital of Verona, Italy, E Bonacci , M Anastasi ,   Deparment of Neuroscience Biomedicine and Movements, University Hospital of Verona, Italy, C Pagnacco ,   Deparment of Neuroscience Biomedicine and Movements, University Hospital of Verona, Italy, G Marchini ,   Chairman and Full Professor of Ophthalmology, Deparment of neuroscience biomedicine and moovments, University Hospital of Verona, Italy, E Pedrotti ,   Associate Professor of Ophthalmology, Deparment of neuroscience biomedicine and moovments, University Hospital of Verona, Italy
Published: March 2024

Corneal topography is a useful investigation in the preoperative cataract surgery planning, becoming mandatory when full refractive outcome is required. Evaluation of corneal power, corneal astigmatism and its management are pivotal to both exclude ectasia, assess the corneal shape and for patient selection. This paper reviews the principles of successive generations of topographers and illustrates several normal and abnormal corneal topographies giving useful indications for refractive cataract surgery.