bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of Business Environment on The Performance of SMIs in The Food and Beverage Sector through Marketplace Adoption as A Mediating Variable
Authors: Choirunnisa Yusti , Koestiono Djoko , Riana Fitria , Muhaimin Abdul , Andriani Dwi
Published: August 2023

This research was conducted at SMIs which was seen from its growth that SMIs had the opportunity to develop in this city. This study aims to describe and analyze the effect of entrepreneurial orientation and the role of government through marketplace adoption on company performance. This study used non-probability sampling with a purposive sampling technique to the owners/managers of companies totaling 50 respondents. This research method is SEM-PLS (Structural Equation Model - Partial Least Square) and uses Warp PLS 7.0 software. The results of the study show that: (1) Marketplace adoption has a positive effect on the SMI performance; (2) Entrepreneurial orientation has a positive and significant effect on marketplace adoption and SMI performance; (3) Role of government has a positive and highly significant effect on marketplace adoption and SMI performance; (4) Adoption of marketplace has a positive and highly significant effect on SMI performance; (5) For the indirect effect, entrepreneurial orientation to company performance through marketplace adoption has a significant positive effect and role of government to company performance through marketplace adoption has a significant positive effect.
The Effect of Multidimensional Consumer Perceived Value on Customer Satisfaction and Purchase Intention of Organic Food
Authors: Rohman Ach , Asmara Rosihan , Andriani Dwi
Published: August 2023

The rapid and widespread growth of the organic food market is considered to become one of the largest growing markets in the food industry. The main objective of this research is to investigate and evaluate the effect of multidimensional consumer perceived value on customer satisfaction and purchase intention in the context of organic food. The data collection was carried out with 234 Indonesian consumers of organic food. The multidimensional consumer perceived value has been formed by 4 dimensions which include functional value, economic value, emotional value, and social value. consumer perceived value is considered to influence customer satisfaction and purchase intention. structural equation modeling (SEM-AMOS) was used to analyze the relationship between them. The result indicates that the consumer perceived value positively influences customer satisfaction and purchase intention. The consumer perceived value has no strong direct influence on purchase intention. Hence, the involvement of customer satisfaction is able to be a full mediator between the customer perceived value and purchase intention. This research contributes to reflecting consumer preferences of organic food in Indonesia as a developing country which is assessed by consumer perceived value, customer satisfaction, and purchase intention.
KARAKTERISTIK KIMIA TEH DAUN RAMBUTAN ACEH (NEPHELUM LAPPACEUM L) DENGAN VARIASI SUHU DAN WAKTU PENGERINGAN
Authors:   Universitas Ahmad Dahlan, Lestari Wiajeng Dayani , Juwitaningtyas Titisari ,   Universitas Ahmad Dahlan
Published: August 2023

Daun rambutan Aceh (Nephelum lappaceum L) mengandung senyawa yang memiliki potensi sebagai antioksidan, sehingga dapat digunakan sebagai teh herbal. Kerusakan senyawa tersebut dapat terjadi jika suhu dan waktu pengeringan tidak tepat. Tujuan penelitian ini adalah untuk mengetahui pengaruh variasi suhu dan waktu pengeringan terhadap karakteristik teh herbal dari daun rambutan Aceh. Penelitian ini menggunakan rancangan acak kelompok (RAK) dengan dua faktor, yaitu variasi suhu (40, 50, 60 °C) dan waktu (120, 150, 180 menit) pengeringan. Variabel yang diamati meliputi karakteristik kimia, seperti fitokimia secara kualitatif, total fenol, aktivitas antioksidan, dan kadar air. Data yang diperoleh diolah menggunakan analisis varian (ANOVA), dan dilakukan uji lanjut dengan uji DMRT untuk hasil yang signifikan. Teh herbal dari daun rambutan Aceh terbukti mengandung saponin, flavonoid, dan tanin. Sampel yang mengalami perlakuan suhu 50 °C selama 120 menit menunjukkan hasil terbaik, dengan kadar air sebesar 7.6%, total fenol sebesar 1.419 mg GAE/g, dan IC50 sebesar 34.106 ppm. Hasil analisis menunjukkan bahwa variasi waktu pengeringan dan suhu pengeringan memiliki pengaruh yang signifikan terhadap karakteristik kimia teh herbal dari daun rambutan Aceh.
EFFECT OF FREQUENCY AND DURATION OF THERMOSONICATION ON THE PHYSICAL, CHEMICAL AND MICROBIOLOGICAL QUALITY OF COW'S MILK
Authors:   Universitas Pembangunan Nasional “Veteran” Jawa Timur, Dhiny Almira Dinar , Jariyah Jariyah ,   Universitas Pembangunan Nasional “Veteran” Jawa Timur, Wicaksono Luqman Agung ,   Universitas Pembangunan Nasional “Veteran” Jawa Timur, Priyanto Anugerah Dany ,   Universitas Pembangunan Nasional “Veteran” Jawa Timur, Safitri Serly ,   Universitas Pembangunan Nasional “Veteran” Jawa Timur, Esfandiar Wildan Naufal ,   Universitas Pembangunan Nasional “Veteran” Jawa Timur
Published: August 2023

Milk is a food product that contains many nutrients. Thermosonication is a method combining ultrasonic and medium-temperature heating that can be used as an alternative pasteurisation method because it can maintain the nutrients contained in milk while providing safety assurance for consumption. This study aimed to determine the effect of frequency and duration of thermosonication on the physical, chemical and microbiological quality of cow's milk. The experimental design used was a completely randomised design (CRD) with two factorials of frequency (20 and 22kHz) and duration of thermosonication (5, 10, 15 and 20 minutes). The data obtained were analysed with ANOVA and BNJ further tests at the 5% level. The best treatment was 22kHz frequency for 20 minutes with the results of viscosity 3.80 ± 0.000 cP, pH 6.8 ± 0.00, fat content 3.22 ± 0.00%, protein content 2.19 ± 0.01% and total bacteria 0.53 ± 0.67 log CFU/ml, and was able to reduce Escherichia coli bacteria by 2.95 log CFU/ml.
Aprendizagem da Docência e o Desenvolvimento Profissional do Professor da Educação Infantil
Authors: Gomes Tiago Pereira , Guedes Neide Cavalcante
Published: August 2023

O artigo objetiva caracterizar como as aprendizagens da docência vão se construindo no movimento da prática de professores da Educação Infantil, que é operacionalizada em sala de aula considerando os diferentes modos de atuação desse professor, o trabalho pedagógico mobilizado pela prática docente e por ações que favorecem os direitos de aprendizagens das crianças, bem como a rotina escolar fundamental para o desenvolvimento de habilidades e competências no ensinar e aprender. Os pressupostos teóricos estão embasados em Pereira (2007), Tardif (2002, 2014), Zabalza (1998, 2000), dentre outros autores. Optamos pela pesquisa narrativa, usando o memorial da prática e a observação sistemática de professoras da Educação Infantil de José de Freitas - PI. Os dados evidenciam que o desenvolvimento profissional docente é ancorado nas aprendizagens da docência desde a trajetória pessoal e percursos formativos da profissão expressados pela rotina das professoras que é orientada pelo sistema municipal de ensino com base no Pacto Nacional de Alfabetização na Idade Certa -PNAIC no sentido de atender aos objetivos, funções e finalidades do nível de ensino em foco.
Memorial Acadêmico, Experiência Monitorial e Aprendizagem Docente (2013-2016)
Authors: Ivo Felipe Cavalcanti , Da Cruz Barbosa Maria da Graça , Guimarães Caravlho Maria Elizete
Published: August 2023

Resumo

Este trabalho é vinculado à História e à Memória, objetivando refletir acerca dos processos formativos da docência, constituídos e/ou (re)elaborados no decorrer do exercício monitorial nas disciplinas de História da Educação/CE/UFPB, entre 2013 e 2016. Os suportes teóricos perpassam a História do Tempo Presente, a Memória e as Representações Sociais. Tendo a escrita de si por método de pesquisa, analisa-se um memorial acadêmico, dialogando com autores, como David (2012), Nóvoa (2013), entre outros, em um processo de releitura sobre a Monitoria, espaço de constituição de identidade professoral, construída na práxis (ação-reflexão-ação). Os resultados indicam o exercício monitorial como elemento pedagógico constitutivo dos sujeitos em formação, concluindo-se que a experiência monitorial fortalece a tríade ensino-pesquisa-extensão e o memorial acadêmico é uma fonte histórica configuradora da docência e da escrita de si.

Palavras-chave: História. Memória. Formação Docente. Monitoria.
Aprendizagem da Docência na Educação Superior
Authors: Teo Carla Rosane Paz Arruda , Alves Solange Maria
Published: August 2023

Com o objetivo de reconhecer possibilidades para qualificar o estágio de docência com vistas à formação de professores bacharéis para a educação superior, foi realizado estudo exploratório-descritivo qualitativo com 11 professores com experiência em supervisão de estágio de docência de pós-graduandos da área da saúde, em Santa Catarina, utilizando instrumento online com três questões abertas sobre potencialidades, fragilidades e possibilidades do estágio. O conteúdo foi analisado e interpretado por cotejamento ao referencial teórico histórico-cultural. Os resultados indicaram a experiência prática como principal potencialidade; como fragilidade, o curto período de tempo e a não obrigatoriedade. Concluiu-se que a possibilidade de qualificar o estágio como estratégia formativa está em sua transformação em atividade de aprendizagem colaborativa e dialógica da docência para pós-graduandos, supervisores e orientadores, em uma lógica de formação inicial, continuada/permanente.
Desenvolvimento Profissional Docente de Professoras Experientes
Authors: Pereira Amarildo Gomes , Anunciato Rosa Maria Moraes
Published: August 2023

Este trabalho, recorte de uma pesquisa de doutorado, norteada na abordagem qualitativa, focaliza o desenvolvimento profissional de professoras experientes inseridas num processo formativo viabilizado pela Rede de Aprendizagem e Desenvolvimento da Docência (ReAD), no 2ºS/2017 e 1º, 2º/2018[1].  Para a escrita deste artigo, analisamos as narrativas produzidas no decorrer da formação ofertada no período citado. Os resultados evidenciam que, as participantes se deparam com grandes desafios para desenvolver o trabalho docente e investirem em seu desenvolvimento profissional. Contudo, mesmo com as condições e trabalho desfavoráveis, elas encontram tempo e disposição para manter-se em processo de formação por meio de estudos individuais, participação em cursos e realização de segunda graduação, especialização e pós-graduação. Diante desses fatos, compreendemos que os programas de formação precisam levar em conta as necessidades formativas da docência em diferentes fases da carreira e as implicações que o trabalho tem na vida pessoal/familiar dos professores, contribuindo para à aquisição de novos conhecimentos, e no auxílio na superação dos entraves para investirem no próprio desenvolvimento profissional.

 

[1]Os participantes da ReAD no momento da realização da inscrição e cadastro foram informados da realização da pesquisa e convidados a assinar o termo de Termo de Consentimento Livre e Esclarecido.
(Re)Vendo a Formação Continuada de Professoras e o Pensamento Algébrico nos Anos Iniciais
Authors: Silva Danielle Abreu , Passos Cármen Lúcia Brancaglion
Published: August 2023

Fruto de uma dissertação, este artigo objetiva compreender que aprendizagens docentes ocorrem no movimento reflexivo de (re)ver tarefas ligadas à unidade temática Álgebra nos primeiros anos de escolarização, especificamente em turmas de 1º, 2º e 3º ano, com professoras que ensinam Matemática. O referencial teórico discute a inclusão do pensamento algébrico nos anos iniciais, como também a formação continuada de professores. Para tanto, valemo-nos de um estudo de natureza qualitativa, com vista ao trabalho colaborativo, no contexto de uma escola pública paulista cujos os instrumentos de produção de dados decorrem de interações propiciadas a partir de reuniões virtuais síncronas (google meet) no horário de Atividade de Trabalho Pedagógico Coletivo (ATPC). Os resultados apontam a necessidade de trabalhos investigativos que sinalizem para "como" pensar tarefas que contribuam para o desenvolvimento do pensamento algébrico, ampliando o conhecimento especializado do professor.
Quais os Desafios do Início na Docência?
Authors: Silva Cavalcante Maria Mikaele da , Gurgel Iure Coutre , Mendonça Luciana de Oliveira Souza
Published: August 2023

Este artigo versa sobre os desafios docentes de professores iniciantes cearenses. O objetivo desta pesquisa foi compreender os desafios dos primeiros anos de atuação como professores no contexto do Ceará. O aporte teórico foi norteado pelos referenciais de: Cruz, Farias e Hobold (2020); Garcia (2010); André (2018). Com relação aos aspectos metodológicos, recorremos a pesquisa-formação, na perspectiva de Delory-Momberger (2008). Os resultados apontam que os professores iniciantes vivem inúmeros desafios nos seus primeiros anos de docência, o que torna esse momento difícil, mas também permeado de intensas aprendizagens, sendo este um processo dinâmico, subjetivo e complexo. Esperamos com este estudo potencializar as discussões na área de formação e atuação de professores.
Conformar comunidades como oportunidad de aprendizaje profesional docente: estudio de casos en Uruguay y Chile
Authors: Tejera Techera Andrea , Questa-Torterolo Mariela , Cabrera Borges Claudia
Published: August 2023

Se presentan resultados del estudio: “Redes e inclusión digital: Incidencias y caracterizaciones para la conformación de comunidades que promueven el aprendizaje profundo en Centros Públicos de Formación Docente de Uruguay y Chile” (proyecto concursable de la Agencia Nacional de Investigación e Innovación y la Fundación Ceibal). El objetivo fue conocer cómo las comunidades y la colaboración emergente, son vistas como una forma de aprendizaje profesional entre los docentes de formación inicial, en centros de Uruguay y Chile. Se organizó en tres fases: 1) identificación y caracterización del conjunto de centros de formación docente de los dos países; 2) estudio de tres casos seleccionados en cada país; 3) validación de expertos e intercambio de experiencias entre los participantes. Los hallazgos muestran que existen diferentes grados de aproximación a la conformación de comunidades, al tiempo que evidencian su relevancia como promotoras de aprendizaje profesional de los docentes.
Necesidades de formadores de formadores respecto a la inclusión de tecnologías digitales
Authors: Cabrera Ana , Pérez Salatto Adriana , Pérez Salatto Marcela
Published: August 2023

Los hallazgos presentados aquí se enmarcan en la investigación denominada PRAXIS 2: re diseño de la formación de docentes con tecnologías digitales. Dicha investigación se realizó en Uruguay en el 2019 con la financiación de la Agencia Nacional de Investigación e Innovación y el Consejo de Formación en Educación de la Administración Nacional de Educación Pública. El enfoque metodológico es de investigación - acción en el marco de comunidades de aprendizaje y de práctica con formadores de formadores. El trabajo con la comunidad incluye tres hitos: identificación de las prácticas (diagnóstico y observación de clases con inclusión de tecnologías digitales), reflexión, y transformación de las prácticas. El presente artículo apunta a comunicar los hallazgos obtenidos a partir de las necesidades expresadas por los participantes al inicio del trabajo. Se concluye que resulta relevante diagnosticar las necesidades de los docentes para la realización de una propuesta formativa “a medida”.

The findings presented here are framed within the research called, PRAXIS 2: redesign of teacher training with digital technologies. This research was carried out in Uruguay in 2019 with the funding from the National Agency for Research and Innovation and the Education Training Council at the National Administration of Public Education. The methodological approach is defined as action research within the framework of learning and practice communities with teacher trainers. The work with the community includes three milestones: identification of practices (diagnosis and observation of classes including digital technologies), reflection and transformation of practices. This article aims at communicating the findings obtained from the needs expressed by the participants at the beginning of the work. It is concluded that it is relevant to diagnose the needs of teachers for the implementation of a “customized” training proposal.

Os achados aqui apresentados fazem parte da pesquisa denominada PRAXIS 2: redesenho da formação de professores com tecnologias digitais. Esta pesquisa foi realizada no Uruguai em 2019 com financiamento da Agência Nacional de Pesquisa e Inovação e do Conselho de Formação Educacional da Administração Nacional de Educação Pública.  O enfoque metodológico é a investigação-ação no quadro de comunidades de aprendizagem e prática com formadores de formadores. O trabalho com a comunidade contempla três momentos: identificação das práticas (diagnóstico e observação das aulas incluindo tecnologias digitais), reflexão e transformação das práticas. Este artigo procura comunicar as constatações obtidas a partir das necessidades expressas pelos participantes no início do trabalho. Conclui-se que é relevante diagnosticar as necessidades dos professores para a realização de uma proposta de formação “customizada”.
Current Treatment Guidelines and Antihypertensive Therapy of Mild Chronic Hypertension During Pregnancy
Authors: Ahn Tae Gyu , Hwang Jong Yun
Published: August 2023

Up to 5% of pregnant females experience chronic hypertension, which is linked to poor pregnancy outcomes, and along with hemorrhage, is considered one of the main causes of maternal morbidity and mortality. The combined occurrence of preeclampsia, cesarean sections, preterm birth, birth weight less than 2,500 g, neonatal unit admission, and perinatal death was higher in females with chronic hypertension. Pregnancy with systolic blood pressure of 140-159 mmHg or diastolic blood pressure of 90-109 mmHg was considered to have mild-to-moderate chronic hypertension. Blood pressure management during pregnancy is a very important issue and is directly related to fetal growth and maternal health. Many studies have reported that antihypertensive therapy during pregnancy halves the incidence of severe hypertension in all types of hypertensive diseases. However, guidelines for optimal blood pressure management goals during pregnancy remain unclear. This is because the benefits to the mother from lowering blood pressure are uncertain, and there is a risk of fetal disorders due to the possibility of reduced uteroplacental blood flow. In light of a recently released CHAP (Chronic Hypertension and Pregnancy) randomized controlled trial, the purpose of this review was to provide a summary of the current recommendations for pregnant females with mild-to-moderate chronic hypertension.
Comparison of Perinatal Outcomes According to the Majority of Physicians: Obstetrics Versus Endocrinology
Authors: Kim Haemin , Cha Hyun-Hwa , Seong Won Joon
Published: August 2023

Purpose: To compare the perinatal outcomes among the majority of physicians who manage pregnancies complicated by gestational diabetes mellitus (GDM), particularly those who require insulin treatment.Methods: We conducted a retrospective study involving 206 singleton pregnant women diagnosed with GDM between January 2017 and September 2022. The study participants were divided into 2 groups according to the majority of physicians (obstetrics vs. endocrinology). We compared the maternal characteristics and perinatal outcomes between the 2 groups and performed a subgroup analysis of preterm birth cases.Results: During the study period, 206 pregnant women were diagnosed with GDM and 36.9% (76 of 206) required insulin treatment. Among the GDM A2 pregnancies, 26 patients visited or consulted endocrinologists, and 50 patients were managed by obstetricians. There were no significant differences in maternal characteristics and perinatal outcomes between the two groups. Eighteen infants were delivered before 37 weeks of gestation (12 in the obstetrician group and 6 in the endocrinologist group). In preterm-delivered patients, the birth weight was heavier in the endocrinology group (median [range], 2.66 [1.98–3.77] vs. 3.71 [2.48–4.17], p=0.025) despite similar gestational age at delivery (median [range], 35.5 [33.1–36.5] vs. 36.0 [34.2–36.6], p=0.511). However, there were no significant differences in perinatal outcomes, including the rate of neonatal hypoglycemia, oxygen treatment and the duration of neonatal intensive care unit admission.Conclusion: Our data show that GDM can be managed by obstetricians even in cases requiring insulin treatment.
Evaluation of Eye Gaze Dynamics During Physician-Patient-Computer Interaction in Federally Qualified Health Centers: Systematic Analysis
Authors: Almansour Amal , Montague Enid , Furst Jacob , Raicu Daniela
Published: August 2023

Background

Understanding the communication between physicians and patients can identify areas where they can improve and build stronger relationships. This led to better patient outcomes including increased engagement, enhanced adherence to treatment plan, and a boost in trust.

Objective

This study investigates eye gaze directions of physicians, patients, and computers in naturalistic medical encounters at Federally Qualified Health Centers to understand communication patterns given different patients’ diverse backgrounds. The aim is to support the building and designing of health information technologies, which will facilitate the improvement of patient outcomes.

Methods

Data were obtained from 77 videotaped medical encounters in 2014 from 3 Federally Qualified Health Centers in Chicago, Illinois, that included 11 physicians and 77 patients. Self-reported surveys were collected from physicians and patients. A systematic analysis approach was used to thoroughly examine and analyze the data. The dynamics of eye gazes during interactions between physicians, patients, and computers were evaluated using the lag sequential analysis method. The objective of the study was to identify significant behavior patterns from the 6 predefined patterns initiated by both physicians and patients. The association between eye gaze patterns was examined using the Pearson chi-square test and the Yule Q test.

Results

The results of the lag sequential method showed that 3 out of 6 doctor-initiated gaze patterns were followed by patient-response gaze patterns. Moreover, 4 out of 6 patient-initiated patterns were significantly followed by doctor-response gaze patterns. Unlike the findings in previous studies, doctor-initiated eye gaze behavior patterns were not leading patients’ eye gaze. Moreover, patient-initiated eye gaze behavior patterns were significant in certain circumstances, particularly when interacting with physicians.

Conclusions

This study examined several physician-patient-computer interaction patterns in naturalistic settings using lag sequential analysis. The data indicated a significant influence of the patients’ gazes on physicians. The findings revealed that physicians demonstrated a higher tendency to engage with patients by reciprocating the patient’s eye gaze when the patient looked at them. However, the reverse pattern was not observed, suggesting a lack of reciprocal gaze from patients toward physicians and a tendency to not direct their gaze toward a specific object. Furthermore, patients exhibited a preference for the computer when physicians directed their eye gaze toward it.
Digital Platform for Continuous Monitoring of Patients Using a Smartwatch: Longitudinal Prospective Cohort Study
Authors: Bin Kaio Jia , De Pretto Lucas Ramos , Sanchez Fábio Beltrame , De Souza e Castro Fabio Pacheco Muniz , Ramos Vinicius Delgado , Battistella Linamara Rizzo
Published: August 2023

Background

Since the COVID-19 pandemic, there has been a boost in the digital transformation of the human society, where wearable devices such as a smartwatch can already measure vital signs in a continuous and naturalistic way; however, the security and privacy of personal data is a challenge to expanding the use of these data by health professionals in clinical follow-up for decision-making. Similar to the European General Data Protection Regulation, in Brazil, the Lei Geral de Proteção de Dados established rules and guidelines for the processing of personal data, including those used for patient care, such as those captured by smartwatches. Thus, in any telemonitoring scenario, there is a need to comply with rules and regulations, making this issue a challenge to overcome.

Objective

This study aimed to build a digital solution model for capturing data from wearable devices and making them available in a safe and agile manner for clinical and research use, following current laws.

Methods

A functional model was built following the Brazilian Lei Geral de Proteção de Dados (2018), where data captured by smartwatches can be transmitted anonymously over the Internet of Things and be identified later within the hospital. A total of 80 volunteers were selected for a 24-week follow-up clinical trial divided into 2 groups, one group with a previous diagnosis of COVID-19 and a control group without a previous diagnosis of COVID-19, to measure the synchronization rate of the platform with the devices and the accuracy and precision of the smartwatch in out-of-hospital conditions to simulate remote monitoring at home.

Results

In a 35-week clinical trial, >11.2 million records were collected with no system downtime; 66% of continuous beats per minute were synchronized within 24 hours (79% within 2 days and 91% within a week). In the limit of agreement analysis, the mean differences in oxygen saturation, diastolic blood pressure, systolic blood pressure, and heart rate were −1.280% (SD 5.679%), −1.399 (SD 19.112) mm Hg, −1.536 (SD 24.244) mm Hg, and 0.566 (SD 3.114) beats per minute, respectively. Furthermore, there was no difference in the 2 study groups in terms of data analysis (neither using the smartwatch nor the gold-standard devices), but it is worth mentioning that all volunteers in the COVID-19 group were already cured of the infection and were highly functional in their daily work life.

Conclusions

On the basis of the results obtained, considering the validation conditions of accuracy and precision and simulating an extrahospital use environment, the functional model built in this study is capable of capturing data from the smartwatch and anonymously providing it to health care services, where they can be treated according to the legislation and be used to support clinical decisions during remote monitoring.
A Web-Based, Respondent-Driven Sampling Survey Among Men Who Have Sex With Men (Kai Noi): Description of Methods and Characteristics (Preprint)
Authors: Karuchit Samart , Thiengtham Panupit , Tanpradech Suvimon , Srinor Watcharapol , Yingyong Thitipong , Naiwatanakul Thananda , Northbrook Sanny , Hladik Wolfgang
Published: August 2023

BACKGROUND

Thailand’s HIV epidemic is heavily concentrated among men who have sex with men (MSM), and surveillance efforts are mostly based on case surveillance and local biobehavioral surveys.

OBJECTIVE

We piloted Kai Noi, a web-based respondent-driven sampling (RDS) survey among MSM.

METHODS

We developed an application coded in PHP that facilitated all procedures and events typically used in an RDS office for use on the web, including e-coupon validation, eligibility screening, consent, interview, peer recruitment, e-coupon issuance, and compensation. All procedures were automated and e-coupon ID numbers were randomly generated. Participants’ phone numbers were the principal means to detect and prevent duplicate enrollment. Sampling took place across Thailand; residents of Bangkok were also invited to attend 1 of 10 clinics for an HIV-related blood draw with additional compensation.

RESULTS

Sampling took place from February to June 2022; seeds (21 at the start, 14 added later) were identified through banner ads, micromessaging, and in online chat rooms. Sampling reached all 6 regions and almost all provinces. Fraudulent (duplicate) enrollment using “borrowed” phone numbers was identified and led to the detection and invalidation of 318 survey records. A further 106 participants did not pass an attention filter question (asking recruits to select a specific categorical response) and were excluded from data analysis, leading to a final data set of 1643 valid participants. Only one record showed signs of straightlining (identical adjacent responses). None of the Bangkok respondents presented for a blood draw.

CONCLUSIONS

We successfully developed an application to implement web-based RDS among MSM across Thailand. Measures to minimize, detect, and eliminate fraudulent survey enrollment are imperative in web-based surveys offering compensation. Efforts to improve biomarker uptake are needed to fully tap the potential of web-based sampling and data collection.
Enabling People with Dementia to self-report data using digital technologies and methods: A narrative literature review (Preprint)
Authors: Kernaghan David , Egan Kieren J , Maguire Roma
Published: August 2023

BACKGROUND

Remote collection of digital self-reported data is becoming more prevalent in health care practice as services adopt a more person-centred care approach and deliver more care at a distance. Whilst the benefits of collecting such data using digital technologies is increasingly being recognised, this can be problematic for People with Dementia who may have additional barriers to self-reporting, especially amongst a population that has traditionally been less technologically literate.

OBJECTIVE

To review the current literature on digital technologies, tools and modalities have been used to collect self-report data in People with Dementia (PwD) and to identify barriers and enablers that influence the ability of PwD to self-report successfully.

METHODS

A narrative review of the literature between 2010 and 2021 was conducted using key search teams across 3 scientific databases, (SCOPUS, PubMed and ACM Digital library). Only studies reporting on PwD using technology for the purpose of self-reporting were included. Articles meeting the inclusion criteria were analysed using Braun and Clarke’s thematic analysis.

RESULTS

A total of 11 articles met our prespecified inclusion criteria. Identified articles demonstrated a prominence for the use of computers over other types of technologies such as mobile phones. Text based modalities were the most common modality used. The most frequently reported tools used were questionnaires including the use of multiple PROMS. Enablers identified included support from informal carers, appropriate set-up at the start of each intervention and offering multiple alternative methods to self-report. Most studies did not identify any significant barriers.

CONCLUSIONS

There is a surprisingly sparse body of literature focused on digital approaches to enable self-reporting from PwD. A clear focus for the field has been the reliance on traditional text-based data collection via a computer whereas approaches making use of more interactive modalities or mobile and smart technology were relatively understudied. As the societal need to deliver person centered care in dementia will continue to grow, it is critical that future technologies are built and implemented in a manner that combines: the breadth of technological, data and modality possibilities with the founding theories of personhood.
Impact of Electronic Health Records on Quality Healthcare at Saint Gregory Catholic Hospital (Preprint)
Authors: Achampong Emmanuel Kusi
Published: August 2023

UNSTRUCTURED

The electronic health record (EHR) is a historically made, utilized, and archived electronic version of a paper graph of a patient's health record. A healthcare entity creates, controls, and maintains a patient's electronic health record. Only health professionals involved in a patient's care can access and utilize an electronic health record. The study's goal is to evaluate the impact of electronic health records on quality healthcare at Saint Gregory Catholic Hospital. The study adopted an explanatory research design and quantitative research approach in which simple random and convenient sampling technique were used to select ninety-two respondents from Saint Gregory Catholic Hospital. The study used structured questionnaires as a tool for data collection. The study found that health professionals at Saint Gregory Catholic Hospital have a good intention on the use of electronic health records. Again, it was discovered that there is a positive and statistically significant effect of electronic health records on quality healthcare.
Modeling Malaria to Assess the Impact of Insecticide Treated Nets and Indoor Residual Spraying Campaigns in Burkina Faso (Preprint)
Authors: Guigma Thierry
Published: August 2023

UNSTRUCTURED

Pilot distributions of ITNs and IRS campaigns took place from 2010 to 2012 in the Diébougou Health District in Burkina Faso. This study aimed to evaluate the effectiveness of these interventions on malaria in this region using machine learning approaches.

The indicator was severe malaria cases among children under five years. We performed a time-series analysis consisting in applying a change point detection algorithm to confirm whether there was a statistically significant change in malaria incidence associated with these interventions. We then proceeded to model the incidence of severe malaria cases to predict the expected malaria cases in Diébougou between 2010 and 2012 as if previous trends had been maintained, and then compared these estimates to the observed cases to quantify the variations induced by these interventions.

The change point analysis revealed that malaria incidence significantly changed in Diébougou after October 2010 (p-value=0.041), corresponding to the first rainy season during which the vector control methods were applied. We modeled severe malaria incidence in Diébougou with a SARIMAX (1, 0, 1) (0, 0, 1) 12 using the average temperature as an exogenous variable to further improve its accuracy. Using this model, we deduced that the implementation of ITNs and IRS was associated with a 50% reduction in severe malaria cases (IC80% = [37%, 64%]) from 2010 to 2012.

The synergy of IRS and ITNs has effectively been associated with declining malaria cases in Diébougou. However, IRS remains an expensive strategy. Future cost-effectiveness studies could help determine a design for better resource allocation.
Selection of Microalgae Harvesting Technology for Bio-crude Oil Production
Authors: Albaqi Abdul Rozaq , Nugroho Dewayanto  , Eko Agus Suyono  , Arief Budiman
Published: August 2023

Energy consumption of fossil fuel which keeps increasing has led to the urgency of research and development on the field  of  renewable  energy  for  the  future. Microalgae are considered to be the most promising new source of biomass compared with first and second-generation feedstocks. A great challenge is a choice of an effective approach for microalgae harvesting. Additional challenges of microalgae harvesting come from the small size of microalgae cells (3-30µm) and the similarity of the density of the microalgae cells to the growth medium. This research is aimed to determine the appropriate microalgae harvesting technology for bio-crude oil production. Several potential microalgae harvesting technologies are centrifugation, filtration, inorganic flocculation, organic flocculation, bioflocculation, electrocoagulation, and flocculation-sedimentation. The  method  used  in  this  research  is Analytic  Hierarchy  Process  (AHP). The  results  indicate  that  the parameters  taken  into  consideration  are  energy need (0.339), cost (0.214), risk of contamination (0.098), efficiency (0.133), technology availability  (0.066),  microalgae strain flexibility (0.079),  and  production time (0.071). In a case study, the pairwise comparison of seven alternatives each for the harvesting and seven criteria are compared. The best alternative that can be recommended as a microalgae harvesting technology is flocculation-sedimentation with a weight of 0.202.
Essential Oils of Etlingera acanthodes A.D. Poulsen, An Endemic Ginger from Sulawesi Island
Authors: Hurria Hurria , Alfian Anggra , Saleh Muhammad Fajri Ramadhan Muslim , Djamaludin Heder , Mursyid Murni , Witno Witno , Mahulette Asri Subkhan
Published: August 2023

Etlingera acanthodes A.D. Poulsen is a ginger endemic to Sulawesi, and there is no research on its essential oils. The Essential oil information of E. acanthodes is the first reported and has a high novelty. The objective of the study is to analyze the component of E. acanthodes essential oils, which are endemic to Sulawesi. The essential oils obtained by hydrodistillation of the leaves, stems, flowers, and rhizomes of E. acanthodes A.D. Poulsen. The samples were analyzed by GC-MS method using the Agilent Technologies 7890 Gas Chromatograph with Auto Sampler. Data analysis of essential oils of GC-MS results were determined based on comparing mass spectra from the NIST 2005 v.2.0 library and Wiley 7 library 2003. The oils of E. acanthodes contain terpenoids, phenolic, steroids, and other compounds. Phenolic compounds (39.56%) predominate in leaves, other compounds (41.25%) on stems, diterpenes hydrocarbons (77.3%) in flowers, and other compounds (43.5%) and steroids (40.4%) on rhizomes. The five main compounds of E. acanthodes are Neophytadiene; (+)-De-O-Methylcentrolobine; Cholest-5-En-3-Ol,23-Ethyl-,(3. Beta.23S)-; 9,12-Octadecadienoic Acid, Phenol, 2-ethyl-. The analysis found several compounds that can be used for industry and medicine in the future.
In silico Determination of Host-Viral Interaction of Apoptotic Mimicry Pathway Proteins During Hepatitis B Viral Pathogenesis
Authors: Sharma Prachie , Rawal Kamal , Kumar Kapila
Published: August 2023

Viruses are the opportunistic pathogens that have developed several elegant strategies to deploy their host systems for a pathogenic invasion. Viral apoptotic mimicry is characterized by the exposure of host cell phospholipid, the phosphatidylserine which marks the host cell for apoptotic activation. The Hepatitis b virus, an enveloped virus has recently been found to interact with Phosphatidylserine (Ptdser) on the host through its large surface protein experimentally. Nonetheless, the employment of apoptotic mimicry during the pathogenesis of HBV has not been determined.  Therefore, in the present study, we attempt the in-silico exploration of the interaction of the apoptosis initiating receptors activated by Phosphatidylserine Receptors such as TIM3, AXL, MERTK and GAS6 by Hepatitis B Virus L protein. Molecular Docking of Phosphatidylserine Receptor were studied to observe protein – protein interaction against Surface L Protein of Hepatitis B Virus by using online protein  interaction software. It was found from the in-silico studies that Phosphatidylserine Receptors i.e. TIM3 (PDB: 5F71), AXL (PDB: 5U6B), MERTK (PDB: 2POC) and Gas6 (Growth Arrest Specific protein 6) (PDB: 2C5D) have shown effective binding efficacy against Surface L Protein of Hepatitis B Virus, whereas TIM3 (PDB: F71) and Gas6 (PDB: 2C5D) has shown maximum binding energy with respect to both the software used to analyse the protein-protein docking. This interaction study can form the basis of the experimental attempt in understanding the viral-host protein interaction pattern during hepatitis b viral infection.
First Report on The Naturalized Alocasia cucullata (Araceae) in Java, Indonesia
Authors: Irsyam Arifin Surya Dwipa , Hariri Muhammad Rifqi , Dewi Asih Perwita , Irwanto Rina Ratnasih
Published: August 2023

The presence of naturalized Alocasia cucullata (Lour.) G.Don (Araceae) in Java is reported for the first time in this paper. The species is an introduced ornamental plant native to India, Sri Lanka, and Indo-China and was only known in cultivation. In this study we collected samples from its naturalized populations in Sukabumi Regency (Cibadak Subdistrict), Sumedang Regency (Jatinangor and Tanjungsari Subdistrict). The observed population grows along the roadside, coastal, ITB Jatinangor green space area, and palm oil plantation. In nature, A. cucullata may spread vegetatively either through root suckers, corms, and stem fragments. The description, distribution map, photographs, and a brief discussion are provided here.
Anti-hypercholesterolemia, Anti-atherogenic, and Anti-hypertension Effects of Red Beetroot (Beta vulgaris L.) in Rats Induced by High Fat and Fructose Diet
Authors: El-Hakim Alim , Sunarti Sunarti , Hidayati Lisna , Widiyanto Slamet
Published: August 2023

Metabolic syndrome is associated with abnormalities of lipid levels in the blood such as hyperlipidemia. Hyperlipidemia conditions can increase the risk of atherosclerosis and hypertension. Beetroot (Beta vulgaris L.) is a plant that contains high antioxidants. Beetroot has the potency to be used as a functional food that can reduce the potential for atherosclerosis and blood pressure. The aim of this study was to examine the effect of beetroot-enriched feed on the cholesterol level, atherogenic index and blood pressure of rats (Rattus norvegicus Berkenhout, 1769) induced by high fat and fructose diet. As many as 25 rats were divided into control, hyperlipidemia, and three treatment groups. The hyperlipidemia and treatment groups were induced to become hyperlipidemia using AIN93-M modified high fat and fructose feed for 8 weeks. The treatment groups were followed by intervention with 6, 9, and 12% beetroot enriched feed for 6 weeks. The feed was prepared by mixing beetroot flour in the pellets. Blood pressure, total cholesterol, and HDL level measurement was conducted after hyperlipidemia induction and after the intervention. The data analyzed with one-way ANOVA, DMRT, and T-Test. The results showed that 6% beetroot intervention have the highest increasing of HDL-cholesterol than other groups. The 9% beetroot intervention significantly decrease total cholesterol lower than normal baseline, and 12% beetroot intervention significantly decrease blood pressure than other groups. The atherogenic index of all treatment group was decreased. The 9% beetroot enriched feed was seen as an optimum dose to reduce total cholesterol, atherogenic index and blood pressure and increase HDL-cholesterol.
Updated Species Check-list of the Indonesian Stingless Bees (Hymenoptera, Apidae, Apinae, Meliponini)
Authors: Trianto Manap , Arisuryanti Tuty , Purwanto Hari , Ubaidillah Rosichon
Published: August 2023

A catalog provides an index to previous studies in taxonomy, behavioral research, and pollination ecology, thus consolidating the existing knowledge in an accessible format. In this study, we explore the annotated catalog and bibliography of the Indonesian meliponini stingless bees (Hymenoptera, Apidae, Apinae, Meliponini). The catalog format is arranged based on Rasmussen (2008). All available literature was reviewed for compiling this catalog and bibliography. References to a Meliponini genus only were not included in the list of references. Cited references must have used a trackable specific epithet to have been included. In total, Indonesia has 52 recorded stingless bee species across the Indonesian archipelagoes of Sumatera (27 species), Java (13 species), Nusa Tenggara (1 species), Kalimantan (34 species), Sulawesi (8 species), Bali (1 species), Maluku (4 species), and Papua (12 species). After the data was updated, there was an increase in the number of stingless bee species in Indonesia, namely 46 species (before update) to 52 species (after update). An up-to-date, comprehensive taxonomic and biological catalog is fundamental to any comparative evolutionary, ecological, and behavioral research on any group of organisms.
The Synergistic Effect of Combination of Pentagamavunone-1 with Diosmin, Galangin, and Piperine in WiDr Colon Cancer Cells: In vitro and Target Protein Prediction
Authors: Ikawati Muthi , Musyayyadah Hajidah , Putri Yurananda Magnalia , Zulfin Ummi Maryam , Wulandari Febri , Putri Dyaningtyas Dewi Pamungkas , Meiyanto Edy
Published: August 2023

Pentagamavunone-1 (PGV-1) is a curcumin analog with a prominent anti-cancer potency in vitro and in vivo for several cancer types, including colon cancer. Combining PGV-1 with natural compounds such as diosmin, galangin, and piperine can enhance its effectiveness due to their promising chemoprevention properties. We aimed to evaluate the effectiveness of combining PGV-1 with diosmin, galangin, or piperine for colon cancer by using in vitro and bioinformatic approaches to predict their target proteins. WiDr cells were used as a model for colon adenocarcinoma (COAD). The cell viability under a single or combination treatment of PGV-1 and diosmin, galangin, or piperine was evaluated using direct counting by the trypan blue exclusion test. SwissTargetProtein, UALCAN, and OncoLnc were utilized to predict target proteins of the compounds in COAD, the expression level of target proteins in COAD, and the survival rate of patients with overexpressed target proteins, respectively. The IC50 values for PGV-1, diosmin, galangin, and piperine were 2.8´10-2 µg/mL, 81 µg/mL, 7 µg/mL, and 172 µg/mL, respectively. All the tested natural compounds showed synergistic effects when combined with PGV-1 at low concentrations. Eleven proteins that were overexpressed in COAD were identified as potential targets. Overlapped predicted targets of PGV-1 and galangin or piperine were CDK1, MET, and TOP2A. The high expression of another set of predicted target proteins, SCD, CA9, and SQLE, led to lower survival rates in COAD patients. We concluded that combinations of PGV-1 with natural compounds can synergistically enhane its anti-cancer activity for colon cancer.
Nutritional Contents and Bioactive Compounds among Several Variants of Dolichos lablab: Fundamental Facts for Functional Food Development
Authors: Purwanti Elly , Hermanto Feri Eko , Prihanta Wahyu , Permana Tutut Indria , Wiwekananda I Gusti Ngurah Agung
Published: August 2023

To date, the data describing various nutritional and secondary metabolites content of Lablab beans is incomplete. Therefore, this study evaluated the nutritional value, secondary metabolites, and antioxidant activity of three different variants of Lablab beans, i.e., brown, black, and cream beans. The results showed that the brown Lablab beans had outperformed other variants according to their nutritional value and flavonoid content with outstanding DPPH scavenging activity. However, the black beans also showed good bioactive contents through their total phenolic percentage with decent reducing activity via the FRAP assay. Those who are keen in developing functional food from Lablab beans should consider this data as a reference.
Aprendizaje computacional para análisis de imágenes de ultrasonido médico
Authors: Arámbula Cosío Fernando , Torres Robles F. , Velásquez-Rodríguez Gustavo A.R. , Galicia Gómez E. , Escalante-Ramirez B. , Olveres J. , L. Pérez Jorge , Medina Bañuelos V. , Camargo Marín L. , Guzmán Huerta M.
Published: August 2023

Las imágenes de ultrasonido médico ofrecen varias ventajas con respecto a otras modalidades como rayos X, tomografía computarizada y resonancia magnética nuclear. Los equipos de ultrasonido son compactos y el tamaño pequeño de la sonda permite al experto tomar imágenes de una amplia variedad de órganos en 2 y 3 dimensiones. Las principales desventajas son un alto nivel de ruido (speckle) en las imágenes y la necesidad de que un experto realice la adquisición de imágenes. En este trabajo presentamos cinco sistemas de análisis computarizado de imágenes de ultrasonido, basados en técnicas de aprendizaje computacional, para mejorar la calidad de la detección de estructuras de interés clínico. Reportamos aplicaciones en: ecocardiografía, salud materno-fetal y oncología.